data_9FG4
# 
_entry.id   9FG4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FG4         pdb_00009fg4 10.2210/pdb9fg4/pdb 
WWPDB D_1292138553 ?            ?                   
EMDB  EMD-50384    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-06-04 ? 
2 'EM metadata'     1 0 2025-06-04 ? 
3 'Additional map'  1 0 2025-06-04 1 
4 FSC               1 0 2025-06-04 ? 
5 'Half map'        1 0 2025-06-04 1 
6 'Half map'        1 0 2025-06-04 2 
7 Image             1 0 2025-06-04 ? 
8 Mask              1 0 2025-06-04 1 
9 'Primary map'     1 0 2025-06-04 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 FSC               repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 'Half map'        repository 'Initial release' ? ? 
7 7 Image             repository 'Initial release' ? ? 
8 8 Mask              repository 'Initial release' ? ? 
9 9 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FG4 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in the long-lived symmetric resting state' 
_pdbx_database_related.db_id          EMD-50384 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              radu@mrc-lmb.cam.ac.uk 
_pdbx_contact_author.name_first         'A. Radu' 
_pdbx_contact_author.name_last          Aricescu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3783-1388 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Mihaylov, D.B.'  1 0000-0002-8375-3360 
'Malinauskas, T.' 2 0000-0002-4847-5529 
'Aricescu, A.R.'  3 0000-0003-3783-1388 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in the long-lived symmetric resting state' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Mihaylov, D.B.'  1 0000-0002-8375-3360 
primary 'Malinauskas, T.' 2 0000-0002-4847-5529 
primary 'Aricescu, A.R.'  3 0000-0003-3783-1388 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Gamma-aminobutyric acid receptor subunit alpha-1' 52916.602 2 ? ? ? ? 
2 polymer     man 'Gamma-aminobutyric acid receptor subunit beta-3' 54444.578 3 ? ? ? ? 
3 branched    man 
;alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
;
910.823   5 ? ? ? ? 
4 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   3 ? ? ? ? 
5 non-polymer syn 
;[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
;
746.566   2 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'GABA(A) receptor subunit alpha-1' 
2 'GABA(A) receptor subunit beta-3'  
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MKKSPGLSDYLWAWTLFLSTLTGRSYGDYKDDDDKQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDI
FVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDG
TLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQS
STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA
MDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS
ATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
;
;MKKSPGLSDYLWAWTLFLSTLTGRSYGDYKDDDDKQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDI
FVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDG
TLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQS
STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA
MDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS
ATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
;
A,D   ? 
2 'polypeptide(L)' no no 
;MCSGLLELLLPIWLSWTLGTRGSEPRSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNM
DYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA
CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLA
LLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGI
QYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
;
;MCSGLLELLLPIWLSWTLGTRGSEPRSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNM
DYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA
CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLA
LLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGI
QYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
;
B,C,E ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        
;[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
;
_pdbx_entity_nonpoly.comp_id     PIO 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   LYS n 
1 4   SER n 
1 5   PRO n 
1 6   GLY n 
1 7   LEU n 
1 8   SER n 
1 9   ASP n 
1 10  TYR n 
1 11  LEU n 
1 12  TRP n 
1 13  ALA n 
1 14  TRP n 
1 15  THR n 
1 16  LEU n 
1 17  PHE n 
1 18  LEU n 
1 19  SER n 
1 20  THR n 
1 21  LEU n 
1 22  THR n 
1 23  GLY n 
1 24  ARG n 
1 25  SER n 
1 26  TYR n 
1 27  GLY n 
1 28  ASP n 
1 29  TYR n 
1 30  LYS n 
1 31  ASP n 
1 32  ASP n 
1 33  ASP n 
1 34  ASP n 
1 35  LYS n 
1 36  GLN n 
1 37  PRO n 
1 38  SER n 
1 39  LEU n 
1 40  GLN n 
1 41  ASP n 
1 42  GLU n 
1 43  LEU n 
1 44  LYS n 
1 45  ASP n 
1 46  ASN n 
1 47  THR n 
1 48  THR n 
1 49  VAL n 
1 50  PHE n 
1 51  THR n 
1 52  ARG n 
1 53  ILE n 
1 54  LEU n 
1 55  ASP n 
1 56  ARG n 
1 57  LEU n 
1 58  LEU n 
1 59  ASP n 
1 60  GLY n 
1 61  TYR n 
1 62  ASP n 
1 63  ASN n 
1 64  ARG n 
1 65  LEU n 
1 66  ARG n 
1 67  PRO n 
1 68  GLY n 
1 69  LEU n 
1 70  GLY n 
1 71  GLU n 
1 72  ARG n 
1 73  VAL n 
1 74  THR n 
1 75  GLU n 
1 76  VAL n 
1 77  LYS n 
1 78  THR n 
1 79  ASP n 
1 80  ILE n 
1 81  PHE n 
1 82  VAL n 
1 83  THR n 
1 84  SER n 
1 85  PHE n 
1 86  GLY n 
1 87  PRO n 
1 88  VAL n 
1 89  SER n 
1 90  ASP n 
1 91  HIS n 
1 92  ASP n 
1 93  MET n 
1 94  GLU n 
1 95  TYR n 
1 96  THR n 
1 97  ILE n 
1 98  ASP n 
1 99  VAL n 
1 100 PHE n 
1 101 PHE n 
1 102 ARG n 
1 103 GLN n 
1 104 SER n 
1 105 TRP n 
1 106 LYS n 
1 107 ASP n 
1 108 GLU n 
1 109 ARG n 
1 110 LEU n 
1 111 LYS n 
1 112 PHE n 
1 113 LYS n 
1 114 GLY n 
1 115 PRO n 
1 116 MET n 
1 117 THR n 
1 118 VAL n 
1 119 LEU n 
1 120 ARG n 
1 121 LEU n 
1 122 ASN n 
1 123 ASN n 
1 124 LEU n 
1 125 MET n 
1 126 ALA n 
1 127 SER n 
1 128 LYS n 
1 129 ILE n 
1 130 TRP n 
1 131 THR n 
1 132 PRO n 
1 133 ASP n 
1 134 THR n 
1 135 PHE n 
1 136 PHE n 
1 137 HIS n 
1 138 ASN n 
1 139 GLY n 
1 140 LYS n 
1 141 LYS n 
1 142 SER n 
1 143 VAL n 
1 144 ALA n 
1 145 HIS n 
1 146 ASN n 
1 147 MET n 
1 148 THR n 
1 149 MET n 
1 150 PRO n 
1 151 ASN n 
1 152 LYS n 
1 153 LEU n 
1 154 LEU n 
1 155 ARG n 
1 156 ILE n 
1 157 THR n 
1 158 GLU n 
1 159 ASP n 
1 160 GLY n 
1 161 THR n 
1 162 LEU n 
1 163 LEU n 
1 164 TYR n 
1 165 THR n 
1 166 MET n 
1 167 ARG n 
1 168 LEU n 
1 169 THR n 
1 170 VAL n 
1 171 ARG n 
1 172 ALA n 
1 173 GLU n 
1 174 CYS n 
1 175 PRO n 
1 176 MET n 
1 177 HIS n 
1 178 LEU n 
1 179 GLU n 
1 180 ASP n 
1 181 PHE n 
1 182 PRO n 
1 183 MET n 
1 184 ASP n 
1 185 ALA n 
1 186 HIS n 
1 187 ALA n 
1 188 CYS n 
1 189 PRO n 
1 190 LEU n 
1 191 LYS n 
1 192 PHE n 
1 193 GLY n 
1 194 SER n 
1 195 TYR n 
1 196 ALA n 
1 197 TYR n 
1 198 THR n 
1 199 ARG n 
1 200 ALA n 
1 201 GLU n 
1 202 VAL n 
1 203 VAL n 
1 204 TYR n 
1 205 GLU n 
1 206 TRP n 
1 207 THR n 
1 208 ARG n 
1 209 GLU n 
1 210 PRO n 
1 211 ALA n 
1 212 ARG n 
1 213 SER n 
1 214 VAL n 
1 215 VAL n 
1 216 VAL n 
1 217 ALA n 
1 218 GLU n 
1 219 ASP n 
1 220 GLY n 
1 221 SER n 
1 222 ARG n 
1 223 LEU n 
1 224 ASN n 
1 225 GLN n 
1 226 TYR n 
1 227 ASP n 
1 228 LEU n 
1 229 LEU n 
1 230 GLY n 
1 231 GLN n 
1 232 THR n 
1 233 VAL n 
1 234 ASP n 
1 235 SER n 
1 236 GLY n 
1 237 ILE n 
1 238 VAL n 
1 239 GLN n 
1 240 SER n 
1 241 SER n 
1 242 THR n 
1 243 GLY n 
1 244 GLU n 
1 245 TYR n 
1 246 VAL n 
1 247 VAL n 
1 248 MET n 
1 249 THR n 
1 250 THR n 
1 251 HIS n 
1 252 PHE n 
1 253 HIS n 
1 254 LEU n 
1 255 LYS n 
1 256 ARG n 
1 257 LYS n 
1 258 ILE n 
1 259 GLY n 
1 260 TYR n 
1 261 PHE n 
1 262 VAL n 
1 263 ILE n 
1 264 GLN n 
1 265 THR n 
1 266 TYR n 
1 267 LEU n 
1 268 PRO n 
1 269 CYS n 
1 270 ILE n 
1 271 MET n 
1 272 THR n 
1 273 VAL n 
1 274 ILE n 
1 275 LEU n 
1 276 SER n 
1 277 GLN n 
1 278 VAL n 
1 279 SER n 
1 280 PHE n 
1 281 TRP n 
1 282 LEU n 
1 283 ASN n 
1 284 ARG n 
1 285 GLU n 
1 286 SER n 
1 287 VAL n 
1 288 PRO n 
1 289 ALA n 
1 290 ARG n 
1 291 THR n 
1 292 VAL n 
1 293 PHE n 
1 294 GLY n 
1 295 VAL n 
1 296 THR n 
1 297 THR n 
1 298 VAL n 
1 299 LEU n 
1 300 THR n 
1 301 MET n 
1 302 THR n 
1 303 THR n 
1 304 LEU n 
1 305 SER n 
1 306 ILE n 
1 307 SER n 
1 308 ALA n 
1 309 ARG n 
1 310 ASN n 
1 311 SER n 
1 312 LEU n 
1 313 PRO n 
1 314 LYS n 
1 315 VAL n 
1 316 ALA n 
1 317 TYR n 
1 318 ALA n 
1 319 THR n 
1 320 ALA n 
1 321 MET n 
1 322 ASP n 
1 323 TRP n 
1 324 PHE n 
1 325 ILE n 
1 326 ALA n 
1 327 VAL n 
1 328 CYS n 
1 329 TYR n 
1 330 ALA n 
1 331 PHE n 
1 332 VAL n 
1 333 PHE n 
1 334 SER n 
1 335 ALA n 
1 336 LEU n 
1 337 ILE n 
1 338 GLU n 
1 339 PHE n 
1 340 ALA n 
1 341 THR n 
1 342 VAL n 
1 343 ASN n 
1 344 TYR n 
1 345 PHE n 
1 346 THR n 
1 347 LYS n 
1 348 ARG n 
1 349 GLY n 
1 350 TYR n 
1 351 ALA n 
1 352 TRP n 
1 353 ASP n 
1 354 GLY n 
1 355 LYS n 
1 356 SER n 
1 357 VAL n 
1 358 VAL n 
1 359 PRO n 
1 360 GLU n 
1 361 LYS n 
1 362 PRO n 
1 363 LYS n 
1 364 LYS n 
1 365 VAL n 
1 366 LYS n 
1 367 ASP n 
1 368 PRO n 
1 369 LEU n 
1 370 ILE n 
1 371 LYS n 
1 372 LYS n 
1 373 ASN n 
1 374 ASN n 
1 375 THR n 
1 376 TYR n 
1 377 ALA n 
1 378 PRO n 
1 379 THR n 
1 380 ALA n 
1 381 THR n 
1 382 SER n 
1 383 TYR n 
1 384 THR n 
1 385 PRO n 
1 386 ASN n 
1 387 LEU n 
1 388 ALA n 
1 389 ARG n 
1 390 GLY n 
1 391 ASP n 
1 392 PRO n 
1 393 GLY n 
1 394 LEU n 
1 395 ALA n 
1 396 THR n 
1 397 ILE n 
1 398 ALA n 
1 399 LYS n 
1 400 SER n 
1 401 ALA n 
1 402 THR n 
1 403 ILE n 
1 404 GLU n 
1 405 PRO n 
1 406 LYS n 
1 407 GLU n 
1 408 VAL n 
1 409 LYS n 
1 410 PRO n 
1 411 GLU n 
1 412 THR n 
1 413 LYS n 
1 414 PRO n 
1 415 PRO n 
1 416 GLU n 
1 417 PRO n 
1 418 LYS n 
1 419 LYS n 
1 420 THR n 
1 421 PHE n 
1 422 ASN n 
1 423 SER n 
1 424 VAL n 
1 425 SER n 
1 426 LYS n 
1 427 ILE n 
1 428 ASP n 
1 429 ARG n 
1 430 LEU n 
1 431 SER n 
1 432 ARG n 
1 433 ILE n 
1 434 ALA n 
1 435 PHE n 
1 436 PRO n 
1 437 LEU n 
1 438 LEU n 
1 439 PHE n 
1 440 GLY n 
1 441 ILE n 
1 442 PHE n 
1 443 ASN n 
1 444 LEU n 
1 445 VAL n 
1 446 TYR n 
1 447 TRP n 
1 448 ALA n 
1 449 THR n 
1 450 TYR n 
1 451 LEU n 
1 452 ASN n 
1 453 ARG n 
1 454 GLU n 
1 455 PRO n 
1 456 GLN n 
1 457 LEU n 
1 458 LYS n 
1 459 ALA n 
1 460 PRO n 
1 461 THR n 
1 462 PRO n 
1 463 HIS n 
1 464 GLN n 
2 1   MET n 
2 2   CYS n 
2 3   SER n 
2 4   GLY n 
2 5   LEU n 
2 6   LEU n 
2 7   GLU n 
2 8   LEU n 
2 9   LEU n 
2 10  LEU n 
2 11  PRO n 
2 12  ILE n 
2 13  TRP n 
2 14  LEU n 
2 15  SER n 
2 16  TRP n 
2 17  THR n 
2 18  LEU n 
2 19  GLY n 
2 20  THR n 
2 21  ARG n 
2 22  GLY n 
2 23  SER n 
2 24  GLU n 
2 25  PRO n 
2 26  ARG n 
2 27  SER n 
2 28  VAL n 
2 29  ASN n 
2 30  ASP n 
2 31  PRO n 
2 32  GLY n 
2 33  ASN n 
2 34  MET n 
2 35  SER n 
2 36  PHE n 
2 37  VAL n 
2 38  LYS n 
2 39  GLU n 
2 40  THR n 
2 41  VAL n 
2 42  ASP n 
2 43  LYS n 
2 44  LEU n 
2 45  LEU n 
2 46  LYS n 
2 47  GLY n 
2 48  TYR n 
2 49  ASP n 
2 50  ILE n 
2 51  ARG n 
2 52  LEU n 
2 53  ARG n 
2 54  PRO n 
2 55  ASP n 
2 56  PHE n 
2 57  GLY n 
2 58  GLY n 
2 59  PRO n 
2 60  PRO n 
2 61  VAL n 
2 62  CYS n 
2 63  VAL n 
2 64  GLY n 
2 65  MET n 
2 66  ASN n 
2 67  ILE n 
2 68  ASP n 
2 69  ILE n 
2 70  ALA n 
2 71  SER n 
2 72  ILE n 
2 73  ASP n 
2 74  MET n 
2 75  VAL n 
2 76  SER n 
2 77  GLU n 
2 78  VAL n 
2 79  ASN n 
2 80  MET n 
2 81  ASP n 
2 82  TYR n 
2 83  THR n 
2 84  LEU n 
2 85  THR n 
2 86  MET n 
2 87  TYR n 
2 88  PHE n 
2 89  GLN n 
2 90  GLN n 
2 91  TYR n 
2 92  TRP n 
2 93  ARG n 
2 94  ASP n 
2 95  LYS n 
2 96  ARG n 
2 97  LEU n 
2 98  ALA n 
2 99  TYR n 
2 100 SER n 
2 101 GLY n 
2 102 ILE n 
2 103 PRO n 
2 104 LEU n 
2 105 ASN n 
2 106 LEU n 
2 107 THR n 
2 108 LEU n 
2 109 ASP n 
2 110 ASN n 
2 111 ARG n 
2 112 VAL n 
2 113 ALA n 
2 114 ASP n 
2 115 GLN n 
2 116 LEU n 
2 117 TRP n 
2 118 VAL n 
2 119 PRO n 
2 120 ASP n 
2 121 THR n 
2 122 TYR n 
2 123 PHE n 
2 124 LEU n 
2 125 ASN n 
2 126 ASP n 
2 127 LYS n 
2 128 LYS n 
2 129 SER n 
2 130 PHE n 
2 131 VAL n 
2 132 HIS n 
2 133 GLY n 
2 134 VAL n 
2 135 THR n 
2 136 VAL n 
2 137 LYS n 
2 138 ASN n 
2 139 ARG n 
2 140 MET n 
2 141 ILE n 
2 142 ARG n 
2 143 LEU n 
2 144 HIS n 
2 145 PRO n 
2 146 ASP n 
2 147 GLY n 
2 148 THR n 
2 149 VAL n 
2 150 LEU n 
2 151 TYR n 
2 152 GLY n 
2 153 LEU n 
2 154 ARG n 
2 155 ILE n 
2 156 THR n 
2 157 THR n 
2 158 THR n 
2 159 ALA n 
2 160 ALA n 
2 161 CYS n 
2 162 MET n 
2 163 MET n 
2 164 ASP n 
2 165 LEU n 
2 166 ARG n 
2 167 ARG n 
2 168 TYR n 
2 169 PRO n 
2 170 LEU n 
2 171 ASP n 
2 172 GLU n 
2 173 GLN n 
2 174 ASN n 
2 175 CYS n 
2 176 THR n 
2 177 LEU n 
2 178 GLU n 
2 179 ILE n 
2 180 GLU n 
2 181 SER n 
2 182 TYR n 
2 183 GLY n 
2 184 TYR n 
2 185 THR n 
2 186 THR n 
2 187 ASP n 
2 188 ASP n 
2 189 ILE n 
2 190 GLU n 
2 191 PHE n 
2 192 TYR n 
2 193 TRP n 
2 194 ARG n 
2 195 GLY n 
2 196 GLY n 
2 197 ASP n 
2 198 LYS n 
2 199 ALA n 
2 200 VAL n 
2 201 THR n 
2 202 GLY n 
2 203 VAL n 
2 204 GLU n 
2 205 ARG n 
2 206 ILE n 
2 207 GLU n 
2 208 LEU n 
2 209 PRO n 
2 210 GLN n 
2 211 PHE n 
2 212 SER n 
2 213 ILE n 
2 214 VAL n 
2 215 GLU n 
2 216 HIS n 
2 217 ARG n 
2 218 LEU n 
2 219 VAL n 
2 220 SER n 
2 221 ARG n 
2 222 ASN n 
2 223 VAL n 
2 224 VAL n 
2 225 PHE n 
2 226 ALA n 
2 227 THR n 
2 228 GLY n 
2 229 ALA n 
2 230 TYR n 
2 231 PRO n 
2 232 ARG n 
2 233 LEU n 
2 234 SER n 
2 235 LEU n 
2 236 SER n 
2 237 PHE n 
2 238 ARG n 
2 239 LEU n 
2 240 LYS n 
2 241 ARG n 
2 242 ASN n 
2 243 ILE n 
2 244 GLY n 
2 245 TYR n 
2 246 PHE n 
2 247 ILE n 
2 248 LEU n 
2 249 GLN n 
2 250 THR n 
2 251 TYR n 
2 252 MET n 
2 253 PRO n 
2 254 SER n 
2 255 ILE n 
2 256 LEU n 
2 257 ILE n 
2 258 THR n 
2 259 ILE n 
2 260 LEU n 
2 261 SER n 
2 262 TRP n 
2 263 VAL n 
2 264 SER n 
2 265 PHE n 
2 266 TRP n 
2 267 ILE n 
2 268 ASN n 
2 269 TYR n 
2 270 ASP n 
2 271 ALA n 
2 272 SER n 
2 273 ALA n 
2 274 ALA n 
2 275 ARG n 
2 276 VAL n 
2 277 ALA n 
2 278 LEU n 
2 279 GLY n 
2 280 ILE n 
2 281 THR n 
2 282 THR n 
2 283 VAL n 
2 284 LEU n 
2 285 THR n 
2 286 MET n 
2 287 THR n 
2 288 THR n 
2 289 ILE n 
2 290 ASN n 
2 291 THR n 
2 292 HIS n 
2 293 LEU n 
2 294 ARG n 
2 295 GLU n 
2 296 THR n 
2 297 LEU n 
2 298 PRO n 
2 299 LYS n 
2 300 ILE n 
2 301 PRO n 
2 302 TYR n 
2 303 VAL n 
2 304 LYS n 
2 305 ALA n 
2 306 ILE n 
2 307 ASP n 
2 308 MET n 
2 309 TYR n 
2 310 LEU n 
2 311 MET n 
2 312 GLY n 
2 313 CYS n 
2 314 PHE n 
2 315 VAL n 
2 316 PHE n 
2 317 VAL n 
2 318 PHE n 
2 319 LEU n 
2 320 ALA n 
2 321 LEU n 
2 322 LEU n 
2 323 GLU n 
2 324 TYR n 
2 325 ALA n 
2 326 PHE n 
2 327 VAL n 
2 328 ASN n 
2 329 TYR n 
2 330 ILE n 
2 331 PHE n 
2 332 PHE n 
2 333 GLY n 
2 334 ARG n 
2 335 GLY n 
2 336 PRO n 
2 337 GLN n 
2 338 ARG n 
2 339 GLN n 
2 340 LYS n 
2 341 LYS n 
2 342 LEU n 
2 343 ALA n 
2 344 GLU n 
2 345 LYS n 
2 346 THR n 
2 347 ALA n 
2 348 LYS n 
2 349 ALA n 
2 350 LYS n 
2 351 ASN n 
2 352 ASP n 
2 353 ARG n 
2 354 SER n 
2 355 LYS n 
2 356 SER n 
2 357 GLU n 
2 358 SER n 
2 359 ASN n 
2 360 ARG n 
2 361 VAL n 
2 362 ASP n 
2 363 ALA n 
2 364 HIS n 
2 365 GLY n 
2 366 ASN n 
2 367 ILE n 
2 368 LEU n 
2 369 LEU n 
2 370 THR n 
2 371 SER n 
2 372 LEU n 
2 373 GLU n 
2 374 VAL n 
2 375 HIS n 
2 376 ASN n 
2 377 GLU n 
2 378 MET n 
2 379 ASN n 
2 380 GLU n 
2 381 VAL n 
2 382 SER n 
2 383 GLY n 
2 384 GLY n 
2 385 ILE n 
2 386 GLY n 
2 387 ASP n 
2 388 THR n 
2 389 ARG n 
2 390 ASN n 
2 391 SER n 
2 392 ALA n 
2 393 ILE n 
2 394 SER n 
2 395 PHE n 
2 396 ASP n 
2 397 ASN n 
2 398 SER n 
2 399 GLY n 
2 400 ILE n 
2 401 GLN n 
2 402 TYR n 
2 403 ARG n 
2 404 LYS n 
2 405 GLN n 
2 406 SER n 
2 407 MET n 
2 408 PRO n 
2 409 ARG n 
2 410 GLU n 
2 411 GLY n 
2 412 HIS n 
2 413 GLY n 
2 414 ARG n 
2 415 PHE n 
2 416 LEU n 
2 417 GLY n 
2 418 ASP n 
2 419 ARG n 
2 420 SER n 
2 421 LEU n 
2 422 PRO n 
2 423 HIS n 
2 424 LYS n 
2 425 LYS n 
2 426 THR n 
2 427 HIS n 
2 428 LEU n 
2 429 ARG n 
2 430 ARG n 
2 431 ARG n 
2 432 SER n 
2 433 SER n 
2 434 GLN n 
2 435 LEU n 
2 436 LYS n 
2 437 ILE n 
2 438 LYS n 
2 439 ILE n 
2 440 PRO n 
2 441 ASP n 
2 442 LEU n 
2 443 THR n 
2 444 ASP n 
2 445 VAL n 
2 446 ASN n 
2 447 ALA n 
2 448 ILE n 
2 449 ASP n 
2 450 ARG n 
2 451 TRP n 
2 452 SER n 
2 453 ARG n 
2 454 ILE n 
2 455 VAL n 
2 456 PHE n 
2 457 PRO n 
2 458 PHE n 
2 459 THR n 
2 460 PHE n 
2 461 SER n 
2 462 LEU n 
2 463 PHE n 
2 464 ASN n 
2 465 LEU n 
2 466 VAL n 
2 467 TYR n 
2 468 TRP n 
2 469 LEU n 
2 470 TYR n 
2 471 TYR n 
2 472 VAL n 
2 473 ASN n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 464 human ? GABRA1 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? 
kidney ? 'kidney; embryo' ? ? ? HEK293S-TetR CRL-1573 ? epithelial-like ? ? plasmid ? 'stable transfection' ? pcDNA4-TO-Zeocin ? ? 
2 1 sample 'Biological sequence' 1 473 human ? GABRB3 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? 
kidney ? 'kidney; embryo' ? ? ? HEK293S-TetR CRL-1573 ? epithelial-like ? ? plasmid ? 'stable transfection' ? 
pcDNA4-TO-hygromycin-B ? ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
3 oligosaccharide 
4 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 3 'DManpa1-3[DManpa1-6]DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-'                                                      
'Glycam Condensed Sequence' GMML       1.0   
2 3 'WURCS=2.0/3,5,4/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3/a4-b1_b4-c1_c3-d1_c6-e1' WURCS PDB2Glycan 
1.1.0 
3 3 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{}}}}}' LINUCS PDB-CARE   
?     
4 4 DGlcpNAcb1-4DGlcpNAcb1-                                                                                     
'Glycam Condensed Sequence' GMML       1.0   
5 4 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1'                                                       WURCS PDB2Glycan 
1.1.0 
6 4 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}}'                                                          LINUCS PDB-CARE   
?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 3 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 3 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
3 3 4 MAN C1 O1 3 BMA O3 HO3 sing ? 
4 3 5 MAN C1 O1 3 BMA O6 HO6 sing ? 
5 4 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose 'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      180.156 
CYS 'L-peptide linking'           y CYSTEINE ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'           y GLUTAMINE ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'           y ISOLEUCINE ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE ? 'C6 H15 N2 O2 1' 147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose 'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6'      180.156 
MET 'L-peptide linking'           y METHIONINE ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE ? 'C9 H11 N O2'    165.189 
PIO non-polymer                   . 
;[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
;
'dioctanoyl l-alpha-phosphatidyl-d-myo-inositol 4,5-diphosphate' 'C25 H49 O19 P3' 746.566 
PRO 'L-peptide linking'           y PROLINE ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                         
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose              
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                       
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -34 ?   ?   ?   A . n 
A 1 2   LYS 2   -33 ?   ?   ?   A . n 
A 1 3   LYS 3   -32 ?   ?   ?   A . n 
A 1 4   SER 4   -31 ?   ?   ?   A . n 
A 1 5   PRO 5   -30 ?   ?   ?   A . n 
A 1 6   GLY 6   -29 ?   ?   ?   A . n 
A 1 7   LEU 7   -28 ?   ?   ?   A . n 
A 1 8   SER 8   -27 ?   ?   ?   A . n 
A 1 9   ASP 9   -26 ?   ?   ?   A . n 
A 1 10  TYR 10  -25 ?   ?   ?   A . n 
A 1 11  LEU 11  -24 ?   ?   ?   A . n 
A 1 12  TRP 12  -23 ?   ?   ?   A . n 
A 1 13  ALA 13  -22 ?   ?   ?   A . n 
A 1 14  TRP 14  -21 ?   ?   ?   A . n 
A 1 15  THR 15  -20 ?   ?   ?   A . n 
A 1 16  LEU 16  -19 ?   ?   ?   A . n 
A 1 17  PHE 17  -18 ?   ?   ?   A . n 
A 1 18  LEU 18  -17 ?   ?   ?   A . n 
A 1 19  SER 19  -16 ?   ?   ?   A . n 
A 1 20  THR 20  -15 ?   ?   ?   A . n 
A 1 21  LEU 21  -14 ?   ?   ?   A . n 
A 1 22  THR 22  -13 ?   ?   ?   A . n 
A 1 23  GLY 23  -12 ?   ?   ?   A . n 
A 1 24  ARG 24  -11 ?   ?   ?   A . n 
A 1 25  SER 25  -10 ?   ?   ?   A . n 
A 1 26  TYR 26  -9  ?   ?   ?   A . n 
A 1 27  GLY 27  -8  ?   ?   ?   A . n 
A 1 28  ASP 28  -7  ?   ?   ?   A . n 
A 1 29  TYR 29  -6  ?   ?   ?   A . n 
A 1 30  LYS 30  -5  ?   ?   ?   A . n 
A 1 31  ASP 31  -4  ?   ?   ?   A . n 
A 1 32  ASP 32  -3  ?   ?   ?   A . n 
A 1 33  ASP 33  -2  ?   ?   ?   A . n 
A 1 34  ASP 34  -1  ?   ?   ?   A . n 
A 1 35  LYS 35  0   ?   ?   ?   A . n 
A 1 36  GLN 36  1   ?   ?   ?   A . n 
A 1 37  PRO 37  2   ?   ?   ?   A . n 
A 1 38  SER 38  3   ?   ?   ?   A . n 
A 1 39  LEU 39  4   ?   ?   ?   A . n 
A 1 40  GLN 40  5   ?   ?   ?   A . n 
A 1 41  ASP 41  6   ?   ?   ?   A . n 
A 1 42  GLU 42  7   ?   ?   ?   A . n 
A 1 43  LEU 43  8   ?   ?   ?   A . n 
A 1 44  LYS 44  9   ?   ?   ?   A . n 
A 1 45  ASP 45  10  ?   ?   ?   A . n 
A 1 46  ASN 46  11  ?   ?   ?   A . n 
A 1 47  THR 47  12  12  THR THR A . n 
A 1 48  THR 48  13  13  THR THR A . n 
A 1 49  VAL 49  14  14  VAL VAL A . n 
A 1 50  PHE 50  15  15  PHE PHE A . n 
A 1 51  THR 51  16  16  THR THR A . n 
A 1 52  ARG 52  17  17  ARG ARG A . n 
A 1 53  ILE 53  18  18  ILE ILE A . n 
A 1 54  LEU 54  19  19  LEU LEU A . n 
A 1 55  ASP 55  20  20  ASP ASP A . n 
A 1 56  ARG 56  21  21  ARG ARG A . n 
A 1 57  LEU 57  22  22  LEU LEU A . n 
A 1 58  LEU 58  23  23  LEU LEU A . n 
A 1 59  ASP 59  24  24  ASP ASP A . n 
A 1 60  GLY 60  25  25  GLY GLY A . n 
A 1 61  TYR 61  26  26  TYR TYR A . n 
A 1 62  ASP 62  27  27  ASP ASP A . n 
A 1 63  ASN 63  28  28  ASN ASN A . n 
A 1 64  ARG 64  29  29  ARG ARG A . n 
A 1 65  LEU 65  30  30  LEU LEU A . n 
A 1 66  ARG 66  31  31  ARG ARG A . n 
A 1 67  PRO 67  32  32  PRO PRO A . n 
A 1 68  GLY 68  33  33  GLY GLY A . n 
A 1 69  LEU 69  34  34  LEU LEU A . n 
A 1 70  GLY 70  35  35  GLY GLY A . n 
A 1 71  GLU 71  36  36  GLU GLU A . n 
A 1 72  ARG 72  37  37  ARG ARG A . n 
A 1 73  VAL 73  38  38  VAL VAL A . n 
A 1 74  THR 74  39  39  THR THR A . n 
A 1 75  GLU 75  40  40  GLU GLU A . n 
A 1 76  VAL 76  41  41  VAL VAL A . n 
A 1 77  LYS 77  42  42  LYS LYS A . n 
A 1 78  THR 78  43  43  THR THR A . n 
A 1 79  ASP 79  44  44  ASP ASP A . n 
A 1 80  ILE 80  45  45  ILE ILE A . n 
A 1 81  PHE 81  46  46  PHE PHE A . n 
A 1 82  VAL 82  47  47  VAL VAL A . n 
A 1 83  THR 83  48  48  THR THR A . n 
A 1 84  SER 84  49  49  SER SER A . n 
A 1 85  PHE 85  50  50  PHE PHE A . n 
A 1 86  GLY 86  51  51  GLY GLY A . n 
A 1 87  PRO 87  52  52  PRO PRO A . n 
A 1 88  VAL 88  53  53  VAL VAL A . n 
A 1 89  SER 89  54  54  SER SER A . n 
A 1 90  ASP 90  55  55  ASP ASP A . n 
A 1 91  HIS 91  56  56  HIS HIS A . n 
A 1 92  ASP 92  57  57  ASP ASP A . n 
A 1 93  MET 93  58  58  MET MET A . n 
A 1 94  GLU 94  59  59  GLU GLU A . n 
A 1 95  TYR 95  60  60  TYR TYR A . n 
A 1 96  THR 96  61  61  THR THR A . n 
A 1 97  ILE 97  62  62  ILE ILE A . n 
A 1 98  ASP 98  63  63  ASP ASP A . n 
A 1 99  VAL 99  64  64  VAL VAL A . n 
A 1 100 PHE 100 65  65  PHE PHE A . n 
A 1 101 PHE 101 66  66  PHE PHE A . n 
A 1 102 ARG 102 67  67  ARG ARG A . n 
A 1 103 GLN 103 68  68  GLN GLN A . n 
A 1 104 SER 104 69  69  SER SER A . n 
A 1 105 TRP 105 70  70  TRP TRP A . n 
A 1 106 LYS 106 71  71  LYS LYS A . n 
A 1 107 ASP 107 72  72  ASP ASP A . n 
A 1 108 GLU 108 73  73  GLU GLU A . n 
A 1 109 ARG 109 74  74  ARG ARG A . n 
A 1 110 LEU 110 75  75  LEU LEU A . n 
A 1 111 LYS 111 76  76  LYS LYS A . n 
A 1 112 PHE 112 77  77  PHE PHE A . n 
A 1 113 LYS 113 78  78  LYS LYS A . n 
A 1 114 GLY 114 79  79  GLY GLY A . n 
A 1 115 PRO 115 80  80  PRO PRO A . n 
A 1 116 MET 116 81  81  MET MET A . n 
A 1 117 THR 117 82  82  THR THR A . n 
A 1 118 VAL 118 83  83  VAL VAL A . n 
A 1 119 LEU 119 84  84  LEU LEU A . n 
A 1 120 ARG 120 85  85  ARG ARG A . n 
A 1 121 LEU 121 86  86  LEU LEU A . n 
A 1 122 ASN 122 87  87  ASN ASN A . n 
A 1 123 ASN 123 88  88  ASN ASN A . n 
A 1 124 LEU 124 89  89  LEU LEU A . n 
A 1 125 MET 125 90  90  MET MET A . n 
A 1 126 ALA 126 91  91  ALA ALA A . n 
A 1 127 SER 127 92  92  SER SER A . n 
A 1 128 LYS 128 93  93  LYS LYS A . n 
A 1 129 ILE 129 94  94  ILE ILE A . n 
A 1 130 TRP 130 95  95  TRP TRP A . n 
A 1 131 THR 131 96  96  THR THR A . n 
A 1 132 PRO 132 97  97  PRO PRO A . n 
A 1 133 ASP 133 98  98  ASP ASP A . n 
A 1 134 THR 134 99  99  THR THR A . n 
A 1 135 PHE 135 100 100 PHE PHE A . n 
A 1 136 PHE 136 101 101 PHE PHE A . n 
A 1 137 HIS 137 102 102 HIS HIS A . n 
A 1 138 ASN 138 103 103 ASN ASN A . n 
A 1 139 GLY 139 104 104 GLY GLY A . n 
A 1 140 LYS 140 105 105 LYS LYS A . n 
A 1 141 LYS 141 106 106 LYS LYS A . n 
A 1 142 SER 142 107 107 SER SER A . n 
A 1 143 VAL 143 108 108 VAL VAL A . n 
A 1 144 ALA 144 109 109 ALA ALA A . n 
A 1 145 HIS 145 110 110 HIS HIS A . n 
A 1 146 ASN 146 111 111 ASN ASN A . n 
A 1 147 MET 147 112 112 MET MET A . n 
A 1 148 THR 148 113 113 THR THR A . n 
A 1 149 MET 149 114 114 MET MET A . n 
A 1 150 PRO 150 115 115 PRO PRO A . n 
A 1 151 ASN 151 116 116 ASN ASN A . n 
A 1 152 LYS 152 117 117 LYS LYS A . n 
A 1 153 LEU 153 118 118 LEU LEU A . n 
A 1 154 LEU 154 119 119 LEU LEU A . n 
A 1 155 ARG 155 120 120 ARG ARG A . n 
A 1 156 ILE 156 121 121 ILE ILE A . n 
A 1 157 THR 157 122 122 THR THR A . n 
A 1 158 GLU 158 123 123 GLU GLU A . n 
A 1 159 ASP 159 124 124 ASP ASP A . n 
A 1 160 GLY 160 125 125 GLY GLY A . n 
A 1 161 THR 161 126 126 THR THR A . n 
A 1 162 LEU 162 127 127 LEU LEU A . n 
A 1 163 LEU 163 128 128 LEU LEU A . n 
A 1 164 TYR 164 129 129 TYR TYR A . n 
A 1 165 THR 165 130 130 THR THR A . n 
A 1 166 MET 166 131 131 MET MET A . n 
A 1 167 ARG 167 132 132 ARG ARG A . n 
A 1 168 LEU 168 133 133 LEU LEU A . n 
A 1 169 THR 169 134 134 THR THR A . n 
A 1 170 VAL 170 135 135 VAL VAL A . n 
A 1 171 ARG 171 136 136 ARG ARG A . n 
A 1 172 ALA 172 137 137 ALA ALA A . n 
A 1 173 GLU 173 138 138 GLU GLU A . n 
A 1 174 CYS 174 139 139 CYS CYS A . n 
A 1 175 PRO 175 140 140 PRO PRO A . n 
A 1 176 MET 176 141 141 MET MET A . n 
A 1 177 HIS 177 142 142 HIS HIS A . n 
A 1 178 LEU 178 143 143 LEU LEU A . n 
A 1 179 GLU 179 144 144 GLU GLU A . n 
A 1 180 ASP 180 145 145 ASP ASP A . n 
A 1 181 PHE 181 146 146 PHE PHE A . n 
A 1 182 PRO 182 147 147 PRO PRO A . n 
A 1 183 MET 183 148 148 MET MET A . n 
A 1 184 ASP 184 149 149 ASP ASP A . n 
A 1 185 ALA 185 150 150 ALA ALA A . n 
A 1 186 HIS 186 151 151 HIS HIS A . n 
A 1 187 ALA 187 152 152 ALA ALA A . n 
A 1 188 CYS 188 153 153 CYS CYS A . n 
A 1 189 PRO 189 154 154 PRO PRO A . n 
A 1 190 LEU 190 155 155 LEU LEU A . n 
A 1 191 LYS 191 156 156 LYS LYS A . n 
A 1 192 PHE 192 157 157 PHE PHE A . n 
A 1 193 GLY 193 158 158 GLY GLY A . n 
A 1 194 SER 194 159 159 SER SER A . n 
A 1 195 TYR 195 160 160 TYR TYR A . n 
A 1 196 ALA 196 161 161 ALA ALA A . n 
A 1 197 TYR 197 162 162 TYR TYR A . n 
A 1 198 THR 198 163 163 THR THR A . n 
A 1 199 ARG 199 164 164 ARG ARG A . n 
A 1 200 ALA 200 165 165 ALA ALA A . n 
A 1 201 GLU 201 166 166 GLU GLU A . n 
A 1 202 VAL 202 167 167 VAL VAL A . n 
A 1 203 VAL 203 168 168 VAL VAL A . n 
A 1 204 TYR 204 169 169 TYR TYR A . n 
A 1 205 GLU 205 170 170 GLU GLU A . n 
A 1 206 TRP 206 171 171 TRP TRP A . n 
A 1 207 THR 207 172 172 THR THR A . n 
A 1 208 ARG 208 173 173 ARG ARG A . n 
A 1 209 GLU 209 174 174 GLU GLU A . n 
A 1 210 PRO 210 175 175 PRO PRO A . n 
A 1 211 ALA 211 176 176 ALA ALA A . n 
A 1 212 ARG 212 177 177 ARG ARG A . n 
A 1 213 SER 213 178 178 SER SER A . n 
A 1 214 VAL 214 179 179 VAL VAL A . n 
A 1 215 VAL 215 180 180 VAL VAL A . n 
A 1 216 VAL 216 181 181 VAL VAL A . n 
A 1 217 ALA 217 182 182 ALA ALA A . n 
A 1 218 GLU 218 183 183 GLU GLU A . n 
A 1 219 ASP 219 184 184 ASP ASP A . n 
A 1 220 GLY 220 185 185 GLY GLY A . n 
A 1 221 SER 221 186 186 SER SER A . n 
A 1 222 ARG 222 187 187 ARG ARG A . n 
A 1 223 LEU 223 188 188 LEU LEU A . n 
A 1 224 ASN 224 189 189 ASN ASN A . n 
A 1 225 GLN 225 190 190 GLN GLN A . n 
A 1 226 TYR 226 191 191 TYR TYR A . n 
A 1 227 ASP 227 192 192 ASP ASP A . n 
A 1 228 LEU 228 193 193 LEU LEU A . n 
A 1 229 LEU 229 194 194 LEU LEU A . n 
A 1 230 GLY 230 195 195 GLY GLY A . n 
A 1 231 GLN 231 196 196 GLN GLN A . n 
A 1 232 THR 232 197 197 THR THR A . n 
A 1 233 VAL 233 198 198 VAL VAL A . n 
A 1 234 ASP 234 199 199 ASP ASP A . n 
A 1 235 SER 235 200 200 SER SER A . n 
A 1 236 GLY 236 201 201 GLY GLY A . n 
A 1 237 ILE 237 202 202 ILE ILE A . n 
A 1 238 VAL 238 203 203 VAL VAL A . n 
A 1 239 GLN 239 204 204 GLN GLN A . n 
A 1 240 SER 240 205 205 SER SER A . n 
A 1 241 SER 241 206 206 SER SER A . n 
A 1 242 THR 242 207 207 THR THR A . n 
A 1 243 GLY 243 208 208 GLY GLY A . n 
A 1 244 GLU 244 209 209 GLU GLU A . n 
A 1 245 TYR 245 210 210 TYR TYR A . n 
A 1 246 VAL 246 211 211 VAL VAL A . n 
A 1 247 VAL 247 212 212 VAL VAL A . n 
A 1 248 MET 248 213 213 MET MET A . n 
A 1 249 THR 249 214 214 THR THR A . n 
A 1 250 THR 250 215 215 THR THR A . n 
A 1 251 HIS 251 216 216 HIS HIS A . n 
A 1 252 PHE 252 217 217 PHE PHE A . n 
A 1 253 HIS 253 218 218 HIS HIS A . n 
A 1 254 LEU 254 219 219 LEU LEU A . n 
A 1 255 LYS 255 220 220 LYS LYS A . n 
A 1 256 ARG 256 221 221 ARG ARG A . n 
A 1 257 LYS 257 222 222 LYS LYS A . n 
A 1 258 ILE 258 223 223 ILE ILE A . n 
A 1 259 GLY 259 224 224 GLY GLY A . n 
A 1 260 TYR 260 225 225 TYR TYR A . n 
A 1 261 PHE 261 226 226 PHE PHE A . n 
A 1 262 VAL 262 227 227 VAL VAL A . n 
A 1 263 ILE 263 228 228 ILE ILE A . n 
A 1 264 GLN 264 229 229 GLN GLN A . n 
A 1 265 THR 265 230 230 THR THR A . n 
A 1 266 TYR 266 231 231 TYR TYR A . n 
A 1 267 LEU 267 232 232 LEU LEU A . n 
A 1 268 PRO 268 233 233 PRO PRO A . n 
A 1 269 CYS 269 234 234 CYS CYS A . n 
A 1 270 ILE 270 235 235 ILE ILE A . n 
A 1 271 MET 271 236 236 MET MET A . n 
A 1 272 THR 272 237 237 THR THR A . n 
A 1 273 VAL 273 238 238 VAL VAL A . n 
A 1 274 ILE 274 239 239 ILE ILE A . n 
A 1 275 LEU 275 240 240 LEU LEU A . n 
A 1 276 SER 276 241 241 SER SER A . n 
A 1 277 GLN 277 242 242 GLN GLN A . n 
A 1 278 VAL 278 243 243 VAL VAL A . n 
A 1 279 SER 279 244 244 SER SER A . n 
A 1 280 PHE 280 245 245 PHE PHE A . n 
A 1 281 TRP 281 246 246 TRP TRP A . n 
A 1 282 LEU 282 247 247 LEU LEU A . n 
A 1 283 ASN 283 248 248 ASN ASN A . n 
A 1 284 ARG 284 249 249 ARG ARG A . n 
A 1 285 GLU 285 250 250 GLU GLU A . n 
A 1 286 SER 286 251 251 SER SER A . n 
A 1 287 VAL 287 252 252 VAL VAL A . n 
A 1 288 PRO 288 253 253 PRO PRO A . n 
A 1 289 ALA 289 254 254 ALA ALA A . n 
A 1 290 ARG 290 255 255 ARG ARG A . n 
A 1 291 THR 291 256 256 THR THR A . n 
A 1 292 VAL 292 257 257 VAL VAL A . n 
A 1 293 PHE 293 258 258 PHE PHE A . n 
A 1 294 GLY 294 259 259 GLY GLY A . n 
A 1 295 VAL 295 260 260 VAL VAL A . n 
A 1 296 THR 296 261 261 THR THR A . n 
A 1 297 THR 297 262 262 THR THR A . n 
A 1 298 VAL 298 263 263 VAL VAL A . n 
A 1 299 LEU 299 264 264 LEU LEU A . n 
A 1 300 THR 300 265 265 THR THR A . n 
A 1 301 MET 301 266 266 MET MET A . n 
A 1 302 THR 302 267 267 THR THR A . n 
A 1 303 THR 303 268 268 THR THR A . n 
A 1 304 LEU 304 269 269 LEU LEU A . n 
A 1 305 SER 305 270 270 SER SER A . n 
A 1 306 ILE 306 271 271 ILE ILE A . n 
A 1 307 SER 307 272 272 SER SER A . n 
A 1 308 ALA 308 273 273 ALA ALA A . n 
A 1 309 ARG 309 274 274 ARG ARG A . n 
A 1 310 ASN 310 275 275 ASN ASN A . n 
A 1 311 SER 311 276 276 SER SER A . n 
A 1 312 LEU 312 277 277 LEU LEU A . n 
A 1 313 PRO 313 278 278 PRO PRO A . n 
A 1 314 LYS 314 279 279 LYS LYS A . n 
A 1 315 VAL 315 280 280 VAL VAL A . n 
A 1 316 ALA 316 281 281 ALA ALA A . n 
A 1 317 TYR 317 282 282 TYR TYR A . n 
A 1 318 ALA 318 283 283 ALA ALA A . n 
A 1 319 THR 319 284 284 THR THR A . n 
A 1 320 ALA 320 285 285 ALA ALA A . n 
A 1 321 MET 321 286 286 MET MET A . n 
A 1 322 ASP 322 287 287 ASP ASP A . n 
A 1 323 TRP 323 288 288 TRP TRP A . n 
A 1 324 PHE 324 289 289 PHE PHE A . n 
A 1 325 ILE 325 290 290 ILE ILE A . n 
A 1 326 ALA 326 291 291 ALA ALA A . n 
A 1 327 VAL 327 292 292 VAL VAL A . n 
A 1 328 CYS 328 293 293 CYS CYS A . n 
A 1 329 TYR 329 294 294 TYR TYR A . n 
A 1 330 ALA 330 295 295 ALA ALA A . n 
A 1 331 PHE 331 296 296 PHE PHE A . n 
A 1 332 VAL 332 297 297 VAL VAL A . n 
A 1 333 PHE 333 298 298 PHE PHE A . n 
A 1 334 SER 334 299 299 SER SER A . n 
A 1 335 ALA 335 300 300 ALA ALA A . n 
A 1 336 LEU 336 301 301 LEU LEU A . n 
A 1 337 ILE 337 302 302 ILE ILE A . n 
A 1 338 GLU 338 303 303 GLU GLU A . n 
A 1 339 PHE 339 304 304 PHE PHE A . n 
A 1 340 ALA 340 305 305 ALA ALA A . n 
A 1 341 THR 341 306 306 THR THR A . n 
A 1 342 VAL 342 307 307 VAL VAL A . n 
A 1 343 ASN 343 308 308 ASN ASN A . n 
A 1 344 TYR 344 309 309 TYR TYR A . n 
A 1 345 PHE 345 310 310 PHE PHE A . n 
A 1 346 THR 346 311 311 THR THR A . n 
A 1 347 LYS 347 312 312 LYS LYS A . n 
A 1 348 ARG 348 313 313 ARG ARG A . n 
A 1 349 GLY 349 314 314 GLY GLY A . n 
A 1 350 TYR 350 315 315 TYR TYR A . n 
A 1 351 ALA 351 316 316 ALA ALA A . n 
A 1 352 TRP 352 317 317 TRP TRP A . n 
A 1 353 ASP 353 318 318 ASP ASP A . n 
A 1 354 GLY 354 319 319 GLY GLY A . n 
A 1 355 LYS 355 320 320 LYS LYS A . n 
A 1 356 SER 356 321 321 SER SER A . n 
A 1 357 VAL 357 322 ?   ?   ?   A . n 
A 1 358 VAL 358 323 ?   ?   ?   A . n 
A 1 359 PRO 359 324 ?   ?   ?   A . n 
A 1 360 GLU 360 325 ?   ?   ?   A . n 
A 1 361 LYS 361 326 ?   ?   ?   A . n 
A 1 362 PRO 362 327 ?   ?   ?   A . n 
A 1 363 LYS 363 328 ?   ?   ?   A . n 
A 1 364 LYS 364 329 ?   ?   ?   A . n 
A 1 365 VAL 365 330 ?   ?   ?   A . n 
A 1 366 LYS 366 331 ?   ?   ?   A . n 
A 1 367 ASP 367 332 ?   ?   ?   A . n 
A 1 368 PRO 368 333 ?   ?   ?   A . n 
A 1 369 LEU 369 334 ?   ?   ?   A . n 
A 1 370 ILE 370 335 ?   ?   ?   A . n 
A 1 371 LYS 371 336 ?   ?   ?   A . n 
A 1 372 LYS 372 337 ?   ?   ?   A . n 
A 1 373 ASN 373 338 ?   ?   ?   A . n 
A 1 374 ASN 374 339 ?   ?   ?   A . n 
A 1 375 THR 375 340 ?   ?   ?   A . n 
A 1 376 TYR 376 341 ?   ?   ?   A . n 
A 1 377 ALA 377 342 ?   ?   ?   A . n 
A 1 378 PRO 378 343 ?   ?   ?   A . n 
A 1 379 THR 379 344 ?   ?   ?   A . n 
A 1 380 ALA 380 345 ?   ?   ?   A . n 
A 1 381 THR 381 346 ?   ?   ?   A . n 
A 1 382 SER 382 347 ?   ?   ?   A . n 
A 1 383 TYR 383 348 ?   ?   ?   A . n 
A 1 384 THR 384 349 ?   ?   ?   A . n 
A 1 385 PRO 385 350 ?   ?   ?   A . n 
A 1 386 ASN 386 351 ?   ?   ?   A . n 
A 1 387 LEU 387 352 ?   ?   ?   A . n 
A 1 388 ALA 388 353 ?   ?   ?   A . n 
A 1 389 ARG 389 354 ?   ?   ?   A . n 
A 1 390 GLY 390 355 ?   ?   ?   A . n 
A 1 391 ASP 391 356 ?   ?   ?   A . n 
A 1 392 PRO 392 357 ?   ?   ?   A . n 
A 1 393 GLY 393 358 ?   ?   ?   A . n 
A 1 394 LEU 394 359 ?   ?   ?   A . n 
A 1 395 ALA 395 360 ?   ?   ?   A . n 
A 1 396 THR 396 361 ?   ?   ?   A . n 
A 1 397 ILE 397 362 ?   ?   ?   A . n 
A 1 398 ALA 398 363 ?   ?   ?   A . n 
A 1 399 LYS 399 364 ?   ?   ?   A . n 
A 1 400 SER 400 365 ?   ?   ?   A . n 
A 1 401 ALA 401 366 ?   ?   ?   A . n 
A 1 402 THR 402 367 ?   ?   ?   A . n 
A 1 403 ILE 403 368 ?   ?   ?   A . n 
A 1 404 GLU 404 369 ?   ?   ?   A . n 
A 1 405 PRO 405 370 ?   ?   ?   A . n 
A 1 406 LYS 406 371 ?   ?   ?   A . n 
A 1 407 GLU 407 372 ?   ?   ?   A . n 
A 1 408 VAL 408 373 ?   ?   ?   A . n 
A 1 409 LYS 409 374 ?   ?   ?   A . n 
A 1 410 PRO 410 375 ?   ?   ?   A . n 
A 1 411 GLU 411 376 ?   ?   ?   A . n 
A 1 412 THR 412 377 ?   ?   ?   A . n 
A 1 413 LYS 413 378 ?   ?   ?   A . n 
A 1 414 PRO 414 379 ?   ?   ?   A . n 
A 1 415 PRO 415 380 ?   ?   ?   A . n 
A 1 416 GLU 416 381 ?   ?   ?   A . n 
A 1 417 PRO 417 382 ?   ?   ?   A . n 
A 1 418 LYS 418 383 ?   ?   ?   A . n 
A 1 419 LYS 419 384 384 LYS LYS A . n 
A 1 420 THR 420 385 385 THR THR A . n 
A 1 421 PHE 421 386 386 PHE PHE A . n 
A 1 422 ASN 422 387 387 ASN ASN A . n 
A 1 423 SER 423 388 388 SER SER A . n 
A 1 424 VAL 424 389 389 VAL VAL A . n 
A 1 425 SER 425 390 390 SER SER A . n 
A 1 426 LYS 426 391 391 LYS LYS A . n 
A 1 427 ILE 427 392 392 ILE ILE A . n 
A 1 428 ASP 428 393 393 ASP ASP A . n 
A 1 429 ARG 429 394 394 ARG ARG A . n 
A 1 430 LEU 430 395 395 LEU LEU A . n 
A 1 431 SER 431 396 396 SER SER A . n 
A 1 432 ARG 432 397 397 ARG ARG A . n 
A 1 433 ILE 433 398 398 ILE ILE A . n 
A 1 434 ALA 434 399 399 ALA ALA A . n 
A 1 435 PHE 435 400 400 PHE PHE A . n 
A 1 436 PRO 436 401 401 PRO PRO A . n 
A 1 437 LEU 437 402 402 LEU LEU A . n 
A 1 438 LEU 438 403 403 LEU LEU A . n 
A 1 439 PHE 439 404 404 PHE PHE A . n 
A 1 440 GLY 440 405 405 GLY GLY A . n 
A 1 441 ILE 441 406 406 ILE ILE A . n 
A 1 442 PHE 442 407 407 PHE PHE A . n 
A 1 443 ASN 443 408 408 ASN ASN A . n 
A 1 444 LEU 444 409 409 LEU LEU A . n 
A 1 445 VAL 445 410 410 VAL VAL A . n 
A 1 446 TYR 446 411 411 TYR TYR A . n 
A 1 447 TRP 447 412 412 TRP TRP A . n 
A 1 448 ALA 448 413 413 ALA ALA A . n 
A 1 449 THR 449 414 414 THR THR A . n 
A 1 450 TYR 450 415 415 TYR TYR A . n 
A 1 451 LEU 451 416 416 LEU LEU A . n 
A 1 452 ASN 452 417 ?   ?   ?   A . n 
A 1 453 ARG 453 418 ?   ?   ?   A . n 
A 1 454 GLU 454 419 ?   ?   ?   A . n 
A 1 455 PRO 455 420 ?   ?   ?   A . n 
A 1 456 GLN 456 421 ?   ?   ?   A . n 
A 1 457 LEU 457 422 ?   ?   ?   A . n 
A 1 458 LYS 458 423 ?   ?   ?   A . n 
A 1 459 ALA 459 424 ?   ?   ?   A . n 
A 1 460 PRO 460 425 ?   ?   ?   A . n 
A 1 461 THR 461 426 ?   ?   ?   A . n 
A 1 462 PRO 462 427 ?   ?   ?   A . n 
A 1 463 HIS 463 428 ?   ?   ?   A . n 
A 1 464 GLN 464 429 ?   ?   ?   A . n 
B 2 1   MET 1   -24 ?   ?   ?   B . n 
B 2 2   CYS 2   -23 ?   ?   ?   B . n 
B 2 3   SER 3   -22 ?   ?   ?   B . n 
B 2 4   GLY 4   -21 ?   ?   ?   B . n 
B 2 5   LEU 5   -20 ?   ?   ?   B . n 
B 2 6   LEU 6   -19 ?   ?   ?   B . n 
B 2 7   GLU 7   -18 ?   ?   ?   B . n 
B 2 8   LEU 8   -17 ?   ?   ?   B . n 
B 2 9   LEU 9   -16 ?   ?   ?   B . n 
B 2 10  LEU 10  -15 ?   ?   ?   B . n 
B 2 11  PRO 11  -14 ?   ?   ?   B . n 
B 2 12  ILE 12  -13 ?   ?   ?   B . n 
B 2 13  TRP 13  -12 ?   ?   ?   B . n 
B 2 14  LEU 14  -11 ?   ?   ?   B . n 
B 2 15  SER 15  -10 ?   ?   ?   B . n 
B 2 16  TRP 16  -9  ?   ?   ?   B . n 
B 2 17  THR 17  -8  ?   ?   ?   B . n 
B 2 18  LEU 18  -7  ?   ?   ?   B . n 
B 2 19  GLY 19  -6  ?   ?   ?   B . n 
B 2 20  THR 20  -5  ?   ?   ?   B . n 
B 2 21  ARG 21  -4  ?   ?   ?   B . n 
B 2 22  GLY 22  -3  ?   ?   ?   B . n 
B 2 23  SER 23  -2  ?   ?   ?   B . n 
B 2 24  GLU 24  -1  ?   ?   ?   B . n 
B 2 25  PRO 25  0   ?   ?   ?   B . n 
B 2 26  ARG 26  1   ?   ?   ?   B . n 
B 2 27  SER 27  2   ?   ?   ?   B . n 
B 2 28  VAL 28  3   ?   ?   ?   B . n 
B 2 29  ASN 29  4   ?   ?   ?   B . n 
B 2 30  ASP 30  5   ?   ?   ?   B . n 
B 2 31  PRO 31  6   ?   ?   ?   B . n 
B 2 32  GLY 32  7   ?   ?   ?   B . n 
B 2 33  ASN 33  8   ?   ?   ?   B . n 
B 2 34  MET 34  9   9   MET MET B . n 
B 2 35  SER 35  10  10  SER SER B . n 
B 2 36  PHE 36  11  11  PHE PHE B . n 
B 2 37  VAL 37  12  12  VAL VAL B . n 
B 2 38  LYS 38  13  13  LYS LYS B . n 
B 2 39  GLU 39  14  14  GLU GLU B . n 
B 2 40  THR 40  15  15  THR THR B . n 
B 2 41  VAL 41  16  16  VAL VAL B . n 
B 2 42  ASP 42  17  17  ASP ASP B . n 
B 2 43  LYS 43  18  18  LYS LYS B . n 
B 2 44  LEU 44  19  19  LEU LEU B . n 
B 2 45  LEU 45  20  20  LEU LEU B . n 
B 2 46  LYS 46  21  21  LYS LYS B . n 
B 2 47  GLY 47  22  22  GLY GLY B . n 
B 2 48  TYR 48  23  23  TYR TYR B . n 
B 2 49  ASP 49  24  24  ASP ASP B . n 
B 2 50  ILE 50  25  25  ILE ILE B . n 
B 2 51  ARG 51  26  26  ARG ARG B . n 
B 2 52  LEU 52  27  27  LEU LEU B . n 
B 2 53  ARG 53  28  28  ARG ARG B . n 
B 2 54  PRO 54  29  29  PRO PRO B . n 
B 2 55  ASP 55  30  30  ASP ASP B . n 
B 2 56  PHE 56  31  31  PHE PHE B . n 
B 2 57  GLY 57  32  32  GLY GLY B . n 
B 2 58  GLY 58  33  33  GLY GLY B . n 
B 2 59  PRO 59  34  34  PRO PRO B . n 
B 2 60  PRO 60  35  35  PRO PRO B . n 
B 2 61  VAL 61  36  36  VAL VAL B . n 
B 2 62  CYS 62  37  37  CYS CYS B . n 
B 2 63  VAL 63  38  38  VAL VAL B . n 
B 2 64  GLY 64  39  39  GLY GLY B . n 
B 2 65  MET 65  40  40  MET MET B . n 
B 2 66  ASN 66  41  41  ASN ASN B . n 
B 2 67  ILE 67  42  42  ILE ILE B . n 
B 2 68  ASP 68  43  43  ASP ASP B . n 
B 2 69  ILE 69  44  44  ILE ILE B . n 
B 2 70  ALA 70  45  45  ALA ALA B . n 
B 2 71  SER 71  46  46  SER SER B . n 
B 2 72  ILE 72  47  47  ILE ILE B . n 
B 2 73  ASP 73  48  48  ASP ASP B . n 
B 2 74  MET 74  49  49  MET MET B . n 
B 2 75  VAL 75  50  50  VAL VAL B . n 
B 2 76  SER 76  51  51  SER SER B . n 
B 2 77  GLU 77  52  52  GLU GLU B . n 
B 2 78  VAL 78  53  53  VAL VAL B . n 
B 2 79  ASN 79  54  54  ASN ASN B . n 
B 2 80  MET 80  55  55  MET MET B . n 
B 2 81  ASP 81  56  56  ASP ASP B . n 
B 2 82  TYR 82  57  57  TYR TYR B . n 
B 2 83  THR 83  58  58  THR THR B . n 
B 2 84  LEU 84  59  59  LEU LEU B . n 
B 2 85  THR 85  60  60  THR THR B . n 
B 2 86  MET 86  61  61  MET MET B . n 
B 2 87  TYR 87  62  62  TYR TYR B . n 
B 2 88  PHE 88  63  63  PHE PHE B . n 
B 2 89  GLN 89  64  64  GLN GLN B . n 
B 2 90  GLN 90  65  65  GLN GLN B . n 
B 2 91  TYR 91  66  66  TYR TYR B . n 
B 2 92  TRP 92  67  67  TRP TRP B . n 
B 2 93  ARG 93  68  68  ARG ARG B . n 
B 2 94  ASP 94  69  69  ASP ASP B . n 
B 2 95  LYS 95  70  70  LYS LYS B . n 
B 2 96  ARG 96  71  71  ARG ARG B . n 
B 2 97  LEU 97  72  72  LEU LEU B . n 
B 2 98  ALA 98  73  73  ALA ALA B . n 
B 2 99  TYR 99  74  74  TYR TYR B . n 
B 2 100 SER 100 75  75  SER SER B . n 
B 2 101 GLY 101 76  76  GLY GLY B . n 
B 2 102 ILE 102 77  77  ILE ILE B . n 
B 2 103 PRO 103 78  78  PRO PRO B . n 
B 2 104 LEU 104 79  79  LEU LEU B . n 
B 2 105 ASN 105 80  80  ASN ASN B . n 
B 2 106 LEU 106 81  81  LEU LEU B . n 
B 2 107 THR 107 82  82  THR THR B . n 
B 2 108 LEU 108 83  83  LEU LEU B . n 
B 2 109 ASP 109 84  84  ASP ASP B . n 
B 2 110 ASN 110 85  85  ASN ASN B . n 
B 2 111 ARG 111 86  86  ARG ARG B . n 
B 2 112 VAL 112 87  87  VAL VAL B . n 
B 2 113 ALA 113 88  88  ALA ALA B . n 
B 2 114 ASP 114 89  89  ASP ASP B . n 
B 2 115 GLN 115 90  90  GLN GLN B . n 
B 2 116 LEU 116 91  91  LEU LEU B . n 
B 2 117 TRP 117 92  92  TRP TRP B . n 
B 2 118 VAL 118 93  93  VAL VAL B . n 
B 2 119 PRO 119 94  94  PRO PRO B . n 
B 2 120 ASP 120 95  95  ASP ASP B . n 
B 2 121 THR 121 96  96  THR THR B . n 
B 2 122 TYR 122 97  97  TYR TYR B . n 
B 2 123 PHE 123 98  98  PHE PHE B . n 
B 2 124 LEU 124 99  99  LEU LEU B . n 
B 2 125 ASN 125 100 100 ASN ASN B . n 
B 2 126 ASP 126 101 101 ASP ASP B . n 
B 2 127 LYS 127 102 102 LYS LYS B . n 
B 2 128 LYS 128 103 103 LYS LYS B . n 
B 2 129 SER 129 104 104 SER SER B . n 
B 2 130 PHE 130 105 105 PHE PHE B . n 
B 2 131 VAL 131 106 106 VAL VAL B . n 
B 2 132 HIS 132 107 107 HIS HIS B . n 
B 2 133 GLY 133 108 108 GLY GLY B . n 
B 2 134 VAL 134 109 109 VAL VAL B . n 
B 2 135 THR 135 110 110 THR THR B . n 
B 2 136 VAL 136 111 111 VAL VAL B . n 
B 2 137 LYS 137 112 112 LYS LYS B . n 
B 2 138 ASN 138 113 113 ASN ASN B . n 
B 2 139 ARG 139 114 114 ARG ARG B . n 
B 2 140 MET 140 115 115 MET MET B . n 
B 2 141 ILE 141 116 116 ILE ILE B . n 
B 2 142 ARG 142 117 117 ARG ARG B . n 
B 2 143 LEU 143 118 118 LEU LEU B . n 
B 2 144 HIS 144 119 119 HIS HIS B . n 
B 2 145 PRO 145 120 120 PRO PRO B . n 
B 2 146 ASP 146 121 121 ASP ASP B . n 
B 2 147 GLY 147 122 122 GLY GLY B . n 
B 2 148 THR 148 123 123 THR THR B . n 
B 2 149 VAL 149 124 124 VAL VAL B . n 
B 2 150 LEU 150 125 125 LEU LEU B . n 
B 2 151 TYR 151 126 126 TYR TYR B . n 
B 2 152 GLY 152 127 127 GLY GLY B . n 
B 2 153 LEU 153 128 128 LEU LEU B . n 
B 2 154 ARG 154 129 129 ARG ARG B . n 
B 2 155 ILE 155 130 130 ILE ILE B . n 
B 2 156 THR 156 131 131 THR THR B . n 
B 2 157 THR 157 132 132 THR THR B . n 
B 2 158 THR 158 133 133 THR THR B . n 
B 2 159 ALA 159 134 134 ALA ALA B . n 
B 2 160 ALA 160 135 135 ALA ALA B . n 
B 2 161 CYS 161 136 136 CYS CYS B . n 
B 2 162 MET 162 137 137 MET MET B . n 
B 2 163 MET 163 138 138 MET MET B . n 
B 2 164 ASP 164 139 139 ASP ASP B . n 
B 2 165 LEU 165 140 140 LEU LEU B . n 
B 2 166 ARG 166 141 141 ARG ARG B . n 
B 2 167 ARG 167 142 142 ARG ARG B . n 
B 2 168 TYR 168 143 143 TYR TYR B . n 
B 2 169 PRO 169 144 144 PRO PRO B . n 
B 2 170 LEU 170 145 145 LEU LEU B . n 
B 2 171 ASP 171 146 146 ASP ASP B . n 
B 2 172 GLU 172 147 147 GLU GLU B . n 
B 2 173 GLN 173 148 148 GLN GLN B . n 
B 2 174 ASN 174 149 149 ASN ASN B . n 
B 2 175 CYS 175 150 150 CYS CYS B . n 
B 2 176 THR 176 151 151 THR THR B . n 
B 2 177 LEU 177 152 152 LEU LEU B . n 
B 2 178 GLU 178 153 153 GLU GLU B . n 
B 2 179 ILE 179 154 154 ILE ILE B . n 
B 2 180 GLU 180 155 155 GLU GLU B . n 
B 2 181 SER 181 156 156 SER SER B . n 
B 2 182 TYR 182 157 157 TYR TYR B . n 
B 2 183 GLY 183 158 158 GLY GLY B . n 
B 2 184 TYR 184 159 159 TYR TYR B . n 
B 2 185 THR 185 160 160 THR THR B . n 
B 2 186 THR 186 161 161 THR THR B . n 
B 2 187 ASP 187 162 162 ASP ASP B . n 
B 2 188 ASP 188 163 163 ASP ASP B . n 
B 2 189 ILE 189 164 164 ILE ILE B . n 
B 2 190 GLU 190 165 165 GLU GLU B . n 
B 2 191 PHE 191 166 166 PHE PHE B . n 
B 2 192 TYR 192 167 167 TYR TYR B . n 
B 2 193 TRP 193 168 168 TRP TRP B . n 
B 2 194 ARG 194 169 169 ARG ARG B . n 
B 2 195 GLY 195 170 170 GLY GLY B . n 
B 2 196 GLY 196 171 171 GLY GLY B . n 
B 2 197 ASP 197 172 172 ASP ASP B . n 
B 2 198 LYS 198 173 173 LYS LYS B . n 
B 2 199 ALA 199 174 174 ALA ALA B . n 
B 2 200 VAL 200 175 175 VAL VAL B . n 
B 2 201 THR 201 176 176 THR THR B . n 
B 2 202 GLY 202 177 177 GLY GLY B . n 
B 2 203 VAL 203 178 178 VAL VAL B . n 
B 2 204 GLU 204 179 179 GLU GLU B . n 
B 2 205 ARG 205 180 180 ARG ARG B . n 
B 2 206 ILE 206 181 181 ILE ILE B . n 
B 2 207 GLU 207 182 182 GLU GLU B . n 
B 2 208 LEU 208 183 183 LEU LEU B . n 
B 2 209 PRO 209 184 184 PRO PRO B . n 
B 2 210 GLN 210 185 185 GLN GLN B . n 
B 2 211 PHE 211 186 186 PHE PHE B . n 
B 2 212 SER 212 187 187 SER SER B . n 
B 2 213 ILE 213 188 188 ILE ILE B . n 
B 2 214 VAL 214 189 189 VAL VAL B . n 
B 2 215 GLU 215 190 190 GLU GLU B . n 
B 2 216 HIS 216 191 191 HIS HIS B . n 
B 2 217 ARG 217 192 192 ARG ARG B . n 
B 2 218 LEU 218 193 193 LEU LEU B . n 
B 2 219 VAL 219 194 194 VAL VAL B . n 
B 2 220 SER 220 195 195 SER SER B . n 
B 2 221 ARG 221 196 196 ARG ARG B . n 
B 2 222 ASN 222 197 197 ASN ASN B . n 
B 2 223 VAL 223 198 198 VAL VAL B . n 
B 2 224 VAL 224 199 199 VAL VAL B . n 
B 2 225 PHE 225 200 200 PHE PHE B . n 
B 2 226 ALA 226 201 201 ALA ALA B . n 
B 2 227 THR 227 202 202 THR THR B . n 
B 2 228 GLY 228 203 203 GLY GLY B . n 
B 2 229 ALA 229 204 204 ALA ALA B . n 
B 2 230 TYR 230 205 205 TYR TYR B . n 
B 2 231 PRO 231 206 206 PRO PRO B . n 
B 2 232 ARG 232 207 207 ARG ARG B . n 
B 2 233 LEU 233 208 208 LEU LEU B . n 
B 2 234 SER 234 209 209 SER SER B . n 
B 2 235 LEU 235 210 210 LEU LEU B . n 
B 2 236 SER 236 211 211 SER SER B . n 
B 2 237 PHE 237 212 212 PHE PHE B . n 
B 2 238 ARG 238 213 213 ARG ARG B . n 
B 2 239 LEU 239 214 214 LEU LEU B . n 
B 2 240 LYS 240 215 215 LYS LYS B . n 
B 2 241 ARG 241 216 216 ARG ARG B . n 
B 2 242 ASN 242 217 217 ASN ASN B . n 
B 2 243 ILE 243 218 218 ILE ILE B . n 
B 2 244 GLY 244 219 219 GLY GLY B . n 
B 2 245 TYR 245 220 220 TYR TYR B . n 
B 2 246 PHE 246 221 221 PHE PHE B . n 
B 2 247 ILE 247 222 222 ILE ILE B . n 
B 2 248 LEU 248 223 223 LEU LEU B . n 
B 2 249 GLN 249 224 224 GLN GLN B . n 
B 2 250 THR 250 225 225 THR THR B . n 
B 2 251 TYR 251 226 226 TYR TYR B . n 
B 2 252 MET 252 227 227 MET MET B . n 
B 2 253 PRO 253 228 228 PRO PRO B . n 
B 2 254 SER 254 229 229 SER SER B . n 
B 2 255 ILE 255 230 230 ILE ILE B . n 
B 2 256 LEU 256 231 231 LEU LEU B . n 
B 2 257 ILE 257 232 232 ILE ILE B . n 
B 2 258 THR 258 233 233 THR THR B . n 
B 2 259 ILE 259 234 234 ILE ILE B . n 
B 2 260 LEU 260 235 235 LEU LEU B . n 
B 2 261 SER 261 236 236 SER SER B . n 
B 2 262 TRP 262 237 237 TRP TRP B . n 
B 2 263 VAL 263 238 238 VAL VAL B . n 
B 2 264 SER 264 239 239 SER SER B . n 
B 2 265 PHE 265 240 240 PHE PHE B . n 
B 2 266 TRP 266 241 241 TRP TRP B . n 
B 2 267 ILE 267 242 242 ILE ILE B . n 
B 2 268 ASN 268 243 243 ASN ASN B . n 
B 2 269 TYR 269 244 244 TYR TYR B . n 
B 2 270 ASP 270 245 245 ASP ASP B . n 
B 2 271 ALA 271 246 246 ALA ALA B . n 
B 2 272 SER 272 247 247 SER SER B . n 
B 2 273 ALA 273 248 248 ALA ALA B . n 
B 2 274 ALA 274 249 249 ALA ALA B . n 
B 2 275 ARG 275 250 250 ARG ARG B . n 
B 2 276 VAL 276 251 251 VAL VAL B . n 
B 2 277 ALA 277 252 252 ALA ALA B . n 
B 2 278 LEU 278 253 253 LEU LEU B . n 
B 2 279 GLY 279 254 254 GLY GLY B . n 
B 2 280 ILE 280 255 255 ILE ILE B . n 
B 2 281 THR 281 256 256 THR THR B . n 
B 2 282 THR 282 257 257 THR THR B . n 
B 2 283 VAL 283 258 258 VAL VAL B . n 
B 2 284 LEU 284 259 259 LEU LEU B . n 
B 2 285 THR 285 260 260 THR THR B . n 
B 2 286 MET 286 261 261 MET MET B . n 
B 2 287 THR 287 262 262 THR THR B . n 
B 2 288 THR 288 263 263 THR THR B . n 
B 2 289 ILE 289 264 264 ILE ILE B . n 
B 2 290 ASN 290 265 265 ASN ASN B . n 
B 2 291 THR 291 266 266 THR THR B . n 
B 2 292 HIS 292 267 267 HIS HIS B . n 
B 2 293 LEU 293 268 268 LEU LEU B . n 
B 2 294 ARG 294 269 269 ARG ARG B . n 
B 2 295 GLU 295 270 270 GLU GLU B . n 
B 2 296 THR 296 271 271 THR THR B . n 
B 2 297 LEU 297 272 272 LEU LEU B . n 
B 2 298 PRO 298 273 273 PRO PRO B . n 
B 2 299 LYS 299 274 274 LYS LYS B . n 
B 2 300 ILE 300 275 275 ILE ILE B . n 
B 2 301 PRO 301 276 276 PRO PRO B . n 
B 2 302 TYR 302 277 277 TYR TYR B . n 
B 2 303 VAL 303 278 278 VAL VAL B . n 
B 2 304 LYS 304 279 279 LYS LYS B . n 
B 2 305 ALA 305 280 280 ALA ALA B . n 
B 2 306 ILE 306 281 281 ILE ILE B . n 
B 2 307 ASP 307 282 282 ASP ASP B . n 
B 2 308 MET 308 283 283 MET MET B . n 
B 2 309 TYR 309 284 284 TYR TYR B . n 
B 2 310 LEU 310 285 285 LEU LEU B . n 
B 2 311 MET 311 286 286 MET MET B . n 
B 2 312 GLY 312 287 287 GLY GLY B . n 
B 2 313 CYS 313 288 288 CYS CYS B . n 
B 2 314 PHE 314 289 289 PHE PHE B . n 
B 2 315 VAL 315 290 290 VAL VAL B . n 
B 2 316 PHE 316 291 291 PHE PHE B . n 
B 2 317 VAL 317 292 292 VAL VAL B . n 
B 2 318 PHE 318 293 293 PHE PHE B . n 
B 2 319 LEU 319 294 294 LEU LEU B . n 
B 2 320 ALA 320 295 295 ALA ALA B . n 
B 2 321 LEU 321 296 296 LEU LEU B . n 
B 2 322 LEU 322 297 297 LEU LEU B . n 
B 2 323 GLU 323 298 298 GLU GLU B . n 
B 2 324 TYR 324 299 299 TYR TYR B . n 
B 2 325 ALA 325 300 300 ALA ALA B . n 
B 2 326 PHE 326 301 301 PHE PHE B . n 
B 2 327 VAL 327 302 302 VAL VAL B . n 
B 2 328 ASN 328 303 303 ASN ASN B . n 
B 2 329 TYR 329 304 304 TYR TYR B . n 
B 2 330 ILE 330 305 305 ILE ILE B . n 
B 2 331 PHE 331 306 306 PHE PHE B . n 
B 2 332 PHE 332 307 307 PHE PHE B . n 
B 2 333 GLY 333 308 308 GLY GLY B . n 
B 2 334 ARG 334 309 309 ARG ARG B . n 
B 2 335 GLY 335 335 ?   ?   ?   B . n 
B 2 336 PRO 336 336 ?   ?   ?   B . n 
B 2 337 GLN 337 337 ?   ?   ?   B . n 
B 2 338 ARG 338 338 ?   ?   ?   B . n 
B 2 339 GLN 339 339 ?   ?   ?   B . n 
B 2 340 LYS 340 340 ?   ?   ?   B . n 
B 2 341 LYS 341 341 ?   ?   ?   B . n 
B 2 342 LEU 342 342 ?   ?   ?   B . n 
B 2 343 ALA 343 343 ?   ?   ?   B . n 
B 2 344 GLU 344 344 ?   ?   ?   B . n 
B 2 345 LYS 345 345 ?   ?   ?   B . n 
B 2 346 THR 346 346 ?   ?   ?   B . n 
B 2 347 ALA 347 347 ?   ?   ?   B . n 
B 2 348 LYS 348 348 ?   ?   ?   B . n 
B 2 349 ALA 349 349 ?   ?   ?   B . n 
B 2 350 LYS 350 350 ?   ?   ?   B . n 
B 2 351 ASN 351 351 ?   ?   ?   B . n 
B 2 352 ASP 352 352 ?   ?   ?   B . n 
B 2 353 ARG 353 353 ?   ?   ?   B . n 
B 2 354 SER 354 354 ?   ?   ?   B . n 
B 2 355 LYS 355 355 ?   ?   ?   B . n 
B 2 356 SER 356 356 ?   ?   ?   B . n 
B 2 357 GLU 357 357 ?   ?   ?   B . n 
B 2 358 SER 358 358 ?   ?   ?   B . n 
B 2 359 ASN 359 359 ?   ?   ?   B . n 
B 2 360 ARG 360 360 ?   ?   ?   B . n 
B 2 361 VAL 361 361 ?   ?   ?   B . n 
B 2 362 ASP 362 362 ?   ?   ?   B . n 
B 2 363 ALA 363 363 ?   ?   ?   B . n 
B 2 364 HIS 364 364 ?   ?   ?   B . n 
B 2 365 GLY 365 365 ?   ?   ?   B . n 
B 2 366 ASN 366 366 ?   ?   ?   B . n 
B 2 367 ILE 367 367 ?   ?   ?   B . n 
B 2 368 LEU 368 368 ?   ?   ?   B . n 
B 2 369 LEU 369 369 ?   ?   ?   B . n 
B 2 370 THR 370 370 ?   ?   ?   B . n 
B 2 371 SER 371 371 ?   ?   ?   B . n 
B 2 372 LEU 372 372 ?   ?   ?   B . n 
B 2 373 GLU 373 373 ?   ?   ?   B . n 
B 2 374 VAL 374 374 ?   ?   ?   B . n 
B 2 375 HIS 375 375 ?   ?   ?   B . n 
B 2 376 ASN 376 376 ?   ?   ?   B . n 
B 2 377 GLU 377 377 ?   ?   ?   B . n 
B 2 378 MET 378 378 ?   ?   ?   B . n 
B 2 379 ASN 379 379 ?   ?   ?   B . n 
B 2 380 GLU 380 380 ?   ?   ?   B . n 
B 2 381 VAL 381 381 ?   ?   ?   B . n 
B 2 382 SER 382 382 ?   ?   ?   B . n 
B 2 383 GLY 383 383 ?   ?   ?   B . n 
B 2 384 GLY 384 384 ?   ?   ?   B . n 
B 2 385 ILE 385 385 ?   ?   ?   B . n 
B 2 386 GLY 386 386 ?   ?   ?   B . n 
B 2 387 ASP 387 387 ?   ?   ?   B . n 
B 2 388 THR 388 388 ?   ?   ?   B . n 
B 2 389 ARG 389 389 ?   ?   ?   B . n 
B 2 390 ASN 390 390 ?   ?   ?   B . n 
B 2 391 SER 391 391 ?   ?   ?   B . n 
B 2 392 ALA 392 392 ?   ?   ?   B . n 
B 2 393 ILE 393 393 ?   ?   ?   B . n 
B 2 394 SER 394 394 ?   ?   ?   B . n 
B 2 395 PHE 395 395 ?   ?   ?   B . n 
B 2 396 ASP 396 396 ?   ?   ?   B . n 
B 2 397 ASN 397 397 ?   ?   ?   B . n 
B 2 398 SER 398 398 ?   ?   ?   B . n 
B 2 399 GLY 399 399 ?   ?   ?   B . n 
B 2 400 ILE 400 400 ?   ?   ?   B . n 
B 2 401 GLN 401 401 ?   ?   ?   B . n 
B 2 402 TYR 402 402 ?   ?   ?   B . n 
B 2 403 ARG 403 403 ?   ?   ?   B . n 
B 2 404 LYS 404 404 ?   ?   ?   B . n 
B 2 405 GLN 405 405 ?   ?   ?   B . n 
B 2 406 SER 406 406 ?   ?   ?   B . n 
B 2 407 MET 407 407 ?   ?   ?   B . n 
B 2 408 PRO 408 408 ?   ?   ?   B . n 
B 2 409 ARG 409 409 ?   ?   ?   B . n 
B 2 410 GLU 410 410 ?   ?   ?   B . n 
B 2 411 GLY 411 411 ?   ?   ?   B . n 
B 2 412 HIS 412 412 ?   ?   ?   B . n 
B 2 413 GLY 413 413 ?   ?   ?   B . n 
B 2 414 ARG 414 414 ?   ?   ?   B . n 
B 2 415 PHE 415 415 ?   ?   ?   B . n 
B 2 416 LEU 416 416 ?   ?   ?   B . n 
B 2 417 GLY 417 417 ?   ?   ?   B . n 
B 2 418 ASP 418 418 ?   ?   ?   B . n 
B 2 419 ARG 419 419 ?   ?   ?   B . n 
B 2 420 SER 420 420 ?   ?   ?   B . n 
B 2 421 LEU 421 421 ?   ?   ?   B . n 
B 2 422 PRO 422 422 ?   ?   ?   B . n 
B 2 423 HIS 423 423 ?   ?   ?   B . n 
B 2 424 LYS 424 424 ?   ?   ?   B . n 
B 2 425 LYS 425 425 ?   ?   ?   B . n 
B 2 426 THR 426 426 ?   ?   ?   B . n 
B 2 427 HIS 427 427 ?   ?   ?   B . n 
B 2 428 LEU 428 428 ?   ?   ?   B . n 
B 2 429 ARG 429 429 ?   ?   ?   B . n 
B 2 430 ARG 430 430 ?   ?   ?   B . n 
B 2 431 ARG 431 431 ?   ?   ?   B . n 
B 2 432 SER 432 432 ?   ?   ?   B . n 
B 2 433 SER 433 433 ?   ?   ?   B . n 
B 2 434 GLN 434 434 ?   ?   ?   B . n 
B 2 435 LEU 435 435 ?   ?   ?   B . n 
B 2 436 LYS 436 436 ?   ?   ?   B . n 
B 2 437 ILE 437 437 ?   ?   ?   B . n 
B 2 438 LYS 438 438 ?   ?   ?   B . n 
B 2 439 ILE 439 439 ?   ?   ?   B . n 
B 2 440 PRO 440 440 ?   ?   ?   B . n 
B 2 441 ASP 441 441 ?   ?   ?   B . n 
B 2 442 LEU 442 442 ?   ?   ?   B . n 
B 2 443 THR 443 443 ?   ?   ?   B . n 
B 2 444 ASP 444 444 444 ASP ASP B . n 
B 2 445 VAL 445 445 445 VAL VAL B . n 
B 2 446 ASN 446 446 446 ASN ASN B . n 
B 2 447 ALA 447 447 447 ALA ALA B . n 
B 2 448 ILE 448 448 448 ILE ILE B . n 
B 2 449 ASP 449 449 449 ASP ASP B . n 
B 2 450 ARG 450 450 450 ARG ARG B . n 
B 2 451 TRP 451 451 451 TRP TRP B . n 
B 2 452 SER 452 452 452 SER SER B . n 
B 2 453 ARG 453 453 453 ARG ARG B . n 
B 2 454 ILE 454 454 454 ILE ILE B . n 
B 2 455 VAL 455 455 455 VAL VAL B . n 
B 2 456 PHE 456 456 456 PHE PHE B . n 
B 2 457 PRO 457 457 457 PRO PRO B . n 
B 2 458 PHE 458 458 458 PHE PHE B . n 
B 2 459 THR 459 459 459 THR THR B . n 
B 2 460 PHE 460 460 460 PHE PHE B . n 
B 2 461 SER 461 461 461 SER SER B . n 
B 2 462 LEU 462 462 462 LEU LEU B . n 
B 2 463 PHE 463 463 463 PHE PHE B . n 
B 2 464 ASN 464 464 464 ASN ASN B . n 
B 2 465 LEU 465 465 465 LEU LEU B . n 
B 2 466 VAL 466 466 466 VAL VAL B . n 
B 2 467 TYR 467 467 467 TYR TYR B . n 
B 2 468 TRP 468 468 468 TRP TRP B . n 
B 2 469 LEU 469 469 469 LEU LEU B . n 
B 2 470 TYR 470 470 470 TYR TYR B . n 
B 2 471 TYR 471 471 471 TYR TYR B . n 
B 2 472 VAL 472 472 472 VAL VAL B . n 
B 2 473 ASN 473 473 ?   ?   ?   B . n 
C 2 1   MET 1   -24 ?   ?   ?   C . n 
C 2 2   CYS 2   -23 ?   ?   ?   C . n 
C 2 3   SER 3   -22 ?   ?   ?   C . n 
C 2 4   GLY 4   -21 ?   ?   ?   C . n 
C 2 5   LEU 5   -20 ?   ?   ?   C . n 
C 2 6   LEU 6   -19 ?   ?   ?   C . n 
C 2 7   GLU 7   -18 ?   ?   ?   C . n 
C 2 8   LEU 8   -17 ?   ?   ?   C . n 
C 2 9   LEU 9   -16 ?   ?   ?   C . n 
C 2 10  LEU 10  -15 ?   ?   ?   C . n 
C 2 11  PRO 11  -14 ?   ?   ?   C . n 
C 2 12  ILE 12  -13 ?   ?   ?   C . n 
C 2 13  TRP 13  -12 ?   ?   ?   C . n 
C 2 14  LEU 14  -11 ?   ?   ?   C . n 
C 2 15  SER 15  -10 ?   ?   ?   C . n 
C 2 16  TRP 16  -9  ?   ?   ?   C . n 
C 2 17  THR 17  -8  ?   ?   ?   C . n 
C 2 18  LEU 18  -7  ?   ?   ?   C . n 
C 2 19  GLY 19  -6  ?   ?   ?   C . n 
C 2 20  THR 20  -5  ?   ?   ?   C . n 
C 2 21  ARG 21  -4  ?   ?   ?   C . n 
C 2 22  GLY 22  -3  ?   ?   ?   C . n 
C 2 23  SER 23  -2  ?   ?   ?   C . n 
C 2 24  GLU 24  -1  ?   ?   ?   C . n 
C 2 25  PRO 25  0   ?   ?   ?   C . n 
C 2 26  ARG 26  1   ?   ?   ?   C . n 
C 2 27  SER 27  2   ?   ?   ?   C . n 
C 2 28  VAL 28  3   ?   ?   ?   C . n 
C 2 29  ASN 29  4   ?   ?   ?   C . n 
C 2 30  ASP 30  5   ?   ?   ?   C . n 
C 2 31  PRO 31  6   ?   ?   ?   C . n 
C 2 32  GLY 32  7   ?   ?   ?   C . n 
C 2 33  ASN 33  8   ?   ?   ?   C . n 
C 2 34  MET 34  9   9   MET MET C . n 
C 2 35  SER 35  10  10  SER SER C . n 
C 2 36  PHE 36  11  11  PHE PHE C . n 
C 2 37  VAL 37  12  12  VAL VAL C . n 
C 2 38  LYS 38  13  13  LYS LYS C . n 
C 2 39  GLU 39  14  14  GLU GLU C . n 
C 2 40  THR 40  15  15  THR THR C . n 
C 2 41  VAL 41  16  16  VAL VAL C . n 
C 2 42  ASP 42  17  17  ASP ASP C . n 
C 2 43  LYS 43  18  18  LYS LYS C . n 
C 2 44  LEU 44  19  19  LEU LEU C . n 
C 2 45  LEU 45  20  20  LEU LEU C . n 
C 2 46  LYS 46  21  21  LYS LYS C . n 
C 2 47  GLY 47  22  22  GLY GLY C . n 
C 2 48  TYR 48  23  23  TYR TYR C . n 
C 2 49  ASP 49  24  24  ASP ASP C . n 
C 2 50  ILE 50  25  25  ILE ILE C . n 
C 2 51  ARG 51  26  26  ARG ARG C . n 
C 2 52  LEU 52  27  27  LEU LEU C . n 
C 2 53  ARG 53  28  28  ARG ARG C . n 
C 2 54  PRO 54  29  29  PRO PRO C . n 
C 2 55  ASP 55  30  30  ASP ASP C . n 
C 2 56  PHE 56  31  31  PHE PHE C . n 
C 2 57  GLY 57  32  32  GLY GLY C . n 
C 2 58  GLY 58  33  33  GLY GLY C . n 
C 2 59  PRO 59  34  34  PRO PRO C . n 
C 2 60  PRO 60  35  35  PRO PRO C . n 
C 2 61  VAL 61  36  36  VAL VAL C . n 
C 2 62  CYS 62  37  37  CYS CYS C . n 
C 2 63  VAL 63  38  38  VAL VAL C . n 
C 2 64  GLY 64  39  39  GLY GLY C . n 
C 2 65  MET 65  40  40  MET MET C . n 
C 2 66  ASN 66  41  41  ASN ASN C . n 
C 2 67  ILE 67  42  42  ILE ILE C . n 
C 2 68  ASP 68  43  43  ASP ASP C . n 
C 2 69  ILE 69  44  44  ILE ILE C . n 
C 2 70  ALA 70  45  45  ALA ALA C . n 
C 2 71  SER 71  46  46  SER SER C . n 
C 2 72  ILE 72  47  47  ILE ILE C . n 
C 2 73  ASP 73  48  48  ASP ASP C . n 
C 2 74  MET 74  49  49  MET MET C . n 
C 2 75  VAL 75  50  50  VAL VAL C . n 
C 2 76  SER 76  51  51  SER SER C . n 
C 2 77  GLU 77  52  52  GLU GLU C . n 
C 2 78  VAL 78  53  53  VAL VAL C . n 
C 2 79  ASN 79  54  54  ASN ASN C . n 
C 2 80  MET 80  55  55  MET MET C . n 
C 2 81  ASP 81  56  56  ASP ASP C . n 
C 2 82  TYR 82  57  57  TYR TYR C . n 
C 2 83  THR 83  58  58  THR THR C . n 
C 2 84  LEU 84  59  59  LEU LEU C . n 
C 2 85  THR 85  60  60  THR THR C . n 
C 2 86  MET 86  61  61  MET MET C . n 
C 2 87  TYR 87  62  62  TYR TYR C . n 
C 2 88  PHE 88  63  63  PHE PHE C . n 
C 2 89  GLN 89  64  64  GLN GLN C . n 
C 2 90  GLN 90  65  65  GLN GLN C . n 
C 2 91  TYR 91  66  66  TYR TYR C . n 
C 2 92  TRP 92  67  67  TRP TRP C . n 
C 2 93  ARG 93  68  68  ARG ARG C . n 
C 2 94  ASP 94  69  69  ASP ASP C . n 
C 2 95  LYS 95  70  70  LYS LYS C . n 
C 2 96  ARG 96  71  71  ARG ARG C . n 
C 2 97  LEU 97  72  72  LEU LEU C . n 
C 2 98  ALA 98  73  73  ALA ALA C . n 
C 2 99  TYR 99  74  74  TYR TYR C . n 
C 2 100 SER 100 75  75  SER SER C . n 
C 2 101 GLY 101 76  76  GLY GLY C . n 
C 2 102 ILE 102 77  77  ILE ILE C . n 
C 2 103 PRO 103 78  78  PRO PRO C . n 
C 2 104 LEU 104 79  79  LEU LEU C . n 
C 2 105 ASN 105 80  80  ASN ASN C . n 
C 2 106 LEU 106 81  81  LEU LEU C . n 
C 2 107 THR 107 82  82  THR THR C . n 
C 2 108 LEU 108 83  83  LEU LEU C . n 
C 2 109 ASP 109 84  84  ASP ASP C . n 
C 2 110 ASN 110 85  85  ASN ASN C . n 
C 2 111 ARG 111 86  86  ARG ARG C . n 
C 2 112 VAL 112 87  87  VAL VAL C . n 
C 2 113 ALA 113 88  88  ALA ALA C . n 
C 2 114 ASP 114 89  89  ASP ASP C . n 
C 2 115 GLN 115 90  90  GLN GLN C . n 
C 2 116 LEU 116 91  91  LEU LEU C . n 
C 2 117 TRP 117 92  92  TRP TRP C . n 
C 2 118 VAL 118 93  93  VAL VAL C . n 
C 2 119 PRO 119 94  94  PRO PRO C . n 
C 2 120 ASP 120 95  95  ASP ASP C . n 
C 2 121 THR 121 96  96  THR THR C . n 
C 2 122 TYR 122 97  97  TYR TYR C . n 
C 2 123 PHE 123 98  98  PHE PHE C . n 
C 2 124 LEU 124 99  99  LEU LEU C . n 
C 2 125 ASN 125 100 100 ASN ASN C . n 
C 2 126 ASP 126 101 101 ASP ASP C . n 
C 2 127 LYS 127 102 102 LYS LYS C . n 
C 2 128 LYS 128 103 103 LYS LYS C . n 
C 2 129 SER 129 104 104 SER SER C . n 
C 2 130 PHE 130 105 105 PHE PHE C . n 
C 2 131 VAL 131 106 106 VAL VAL C . n 
C 2 132 HIS 132 107 107 HIS HIS C . n 
C 2 133 GLY 133 108 108 GLY GLY C . n 
C 2 134 VAL 134 109 109 VAL VAL C . n 
C 2 135 THR 135 110 110 THR THR C . n 
C 2 136 VAL 136 111 111 VAL VAL C . n 
C 2 137 LYS 137 112 112 LYS LYS C . n 
C 2 138 ASN 138 113 113 ASN ASN C . n 
C 2 139 ARG 139 114 114 ARG ARG C . n 
C 2 140 MET 140 115 115 MET MET C . n 
C 2 141 ILE 141 116 116 ILE ILE C . n 
C 2 142 ARG 142 117 117 ARG ARG C . n 
C 2 143 LEU 143 118 118 LEU LEU C . n 
C 2 144 HIS 144 119 119 HIS HIS C . n 
C 2 145 PRO 145 120 120 PRO PRO C . n 
C 2 146 ASP 146 121 121 ASP ASP C . n 
C 2 147 GLY 147 122 122 GLY GLY C . n 
C 2 148 THR 148 123 123 THR THR C . n 
C 2 149 VAL 149 124 124 VAL VAL C . n 
C 2 150 LEU 150 125 125 LEU LEU C . n 
C 2 151 TYR 151 126 126 TYR TYR C . n 
C 2 152 GLY 152 127 127 GLY GLY C . n 
C 2 153 LEU 153 128 128 LEU LEU C . n 
C 2 154 ARG 154 129 129 ARG ARG C . n 
C 2 155 ILE 155 130 130 ILE ILE C . n 
C 2 156 THR 156 131 131 THR THR C . n 
C 2 157 THR 157 132 132 THR THR C . n 
C 2 158 THR 158 133 133 THR THR C . n 
C 2 159 ALA 159 134 134 ALA ALA C . n 
C 2 160 ALA 160 135 135 ALA ALA C . n 
C 2 161 CYS 161 136 136 CYS CYS C . n 
C 2 162 MET 162 137 137 MET MET C . n 
C 2 163 MET 163 138 138 MET MET C . n 
C 2 164 ASP 164 139 139 ASP ASP C . n 
C 2 165 LEU 165 140 140 LEU LEU C . n 
C 2 166 ARG 166 141 141 ARG ARG C . n 
C 2 167 ARG 167 142 142 ARG ARG C . n 
C 2 168 TYR 168 143 143 TYR TYR C . n 
C 2 169 PRO 169 144 144 PRO PRO C . n 
C 2 170 LEU 170 145 145 LEU LEU C . n 
C 2 171 ASP 171 146 146 ASP ASP C . n 
C 2 172 GLU 172 147 147 GLU GLU C . n 
C 2 173 GLN 173 148 148 GLN GLN C . n 
C 2 174 ASN 174 149 149 ASN ASN C . n 
C 2 175 CYS 175 150 150 CYS CYS C . n 
C 2 176 THR 176 151 151 THR THR C . n 
C 2 177 LEU 177 152 152 LEU LEU C . n 
C 2 178 GLU 178 153 153 GLU GLU C . n 
C 2 179 ILE 179 154 154 ILE ILE C . n 
C 2 180 GLU 180 155 155 GLU GLU C . n 
C 2 181 SER 181 156 156 SER SER C . n 
C 2 182 TYR 182 157 157 TYR TYR C . n 
C 2 183 GLY 183 158 158 GLY GLY C . n 
C 2 184 TYR 184 159 159 TYR TYR C . n 
C 2 185 THR 185 160 160 THR THR C . n 
C 2 186 THR 186 161 161 THR THR C . n 
C 2 187 ASP 187 162 162 ASP ASP C . n 
C 2 188 ASP 188 163 163 ASP ASP C . n 
C 2 189 ILE 189 164 164 ILE ILE C . n 
C 2 190 GLU 190 165 165 GLU GLU C . n 
C 2 191 PHE 191 166 166 PHE PHE C . n 
C 2 192 TYR 192 167 167 TYR TYR C . n 
C 2 193 TRP 193 168 168 TRP TRP C . n 
C 2 194 ARG 194 169 169 ARG ARG C . n 
C 2 195 GLY 195 170 170 GLY GLY C . n 
C 2 196 GLY 196 171 171 GLY GLY C . n 
C 2 197 ASP 197 172 172 ASP ASP C . n 
C 2 198 LYS 198 173 173 LYS LYS C . n 
C 2 199 ALA 199 174 174 ALA ALA C . n 
C 2 200 VAL 200 175 175 VAL VAL C . n 
C 2 201 THR 201 176 176 THR THR C . n 
C 2 202 GLY 202 177 177 GLY GLY C . n 
C 2 203 VAL 203 178 178 VAL VAL C . n 
C 2 204 GLU 204 179 179 GLU GLU C . n 
C 2 205 ARG 205 180 180 ARG ARG C . n 
C 2 206 ILE 206 181 181 ILE ILE C . n 
C 2 207 GLU 207 182 182 GLU GLU C . n 
C 2 208 LEU 208 183 183 LEU LEU C . n 
C 2 209 PRO 209 184 184 PRO PRO C . n 
C 2 210 GLN 210 185 185 GLN GLN C . n 
C 2 211 PHE 211 186 186 PHE PHE C . n 
C 2 212 SER 212 187 187 SER SER C . n 
C 2 213 ILE 213 188 188 ILE ILE C . n 
C 2 214 VAL 214 189 189 VAL VAL C . n 
C 2 215 GLU 215 190 190 GLU GLU C . n 
C 2 216 HIS 216 191 191 HIS HIS C . n 
C 2 217 ARG 217 192 192 ARG ARG C . n 
C 2 218 LEU 218 193 193 LEU LEU C . n 
C 2 219 VAL 219 194 194 VAL VAL C . n 
C 2 220 SER 220 195 195 SER SER C . n 
C 2 221 ARG 221 196 196 ARG ARG C . n 
C 2 222 ASN 222 197 197 ASN ASN C . n 
C 2 223 VAL 223 198 198 VAL VAL C . n 
C 2 224 VAL 224 199 199 VAL VAL C . n 
C 2 225 PHE 225 200 200 PHE PHE C . n 
C 2 226 ALA 226 201 201 ALA ALA C . n 
C 2 227 THR 227 202 202 THR THR C . n 
C 2 228 GLY 228 203 203 GLY GLY C . n 
C 2 229 ALA 229 204 204 ALA ALA C . n 
C 2 230 TYR 230 205 205 TYR TYR C . n 
C 2 231 PRO 231 206 206 PRO PRO C . n 
C 2 232 ARG 232 207 207 ARG ARG C . n 
C 2 233 LEU 233 208 208 LEU LEU C . n 
C 2 234 SER 234 209 209 SER SER C . n 
C 2 235 LEU 235 210 210 LEU LEU C . n 
C 2 236 SER 236 211 211 SER SER C . n 
C 2 237 PHE 237 212 212 PHE PHE C . n 
C 2 238 ARG 238 213 213 ARG ARG C . n 
C 2 239 LEU 239 214 214 LEU LEU C . n 
C 2 240 LYS 240 215 215 LYS LYS C . n 
C 2 241 ARG 241 216 216 ARG ARG C . n 
C 2 242 ASN 242 217 217 ASN ASN C . n 
C 2 243 ILE 243 218 218 ILE ILE C . n 
C 2 244 GLY 244 219 219 GLY GLY C . n 
C 2 245 TYR 245 220 220 TYR TYR C . n 
C 2 246 PHE 246 221 221 PHE PHE C . n 
C 2 247 ILE 247 222 222 ILE ILE C . n 
C 2 248 LEU 248 223 223 LEU LEU C . n 
C 2 249 GLN 249 224 224 GLN GLN C . n 
C 2 250 THR 250 225 225 THR THR C . n 
C 2 251 TYR 251 226 226 TYR TYR C . n 
C 2 252 MET 252 227 227 MET MET C . n 
C 2 253 PRO 253 228 228 PRO PRO C . n 
C 2 254 SER 254 229 229 SER SER C . n 
C 2 255 ILE 255 230 230 ILE ILE C . n 
C 2 256 LEU 256 231 231 LEU LEU C . n 
C 2 257 ILE 257 232 232 ILE ILE C . n 
C 2 258 THR 258 233 233 THR THR C . n 
C 2 259 ILE 259 234 234 ILE ILE C . n 
C 2 260 LEU 260 235 235 LEU LEU C . n 
C 2 261 SER 261 236 236 SER SER C . n 
C 2 262 TRP 262 237 237 TRP TRP C . n 
C 2 263 VAL 263 238 238 VAL VAL C . n 
C 2 264 SER 264 239 239 SER SER C . n 
C 2 265 PHE 265 240 240 PHE PHE C . n 
C 2 266 TRP 266 241 241 TRP TRP C . n 
C 2 267 ILE 267 242 242 ILE ILE C . n 
C 2 268 ASN 268 243 243 ASN ASN C . n 
C 2 269 TYR 269 244 244 TYR TYR C . n 
C 2 270 ASP 270 245 245 ASP ASP C . n 
C 2 271 ALA 271 246 246 ALA ALA C . n 
C 2 272 SER 272 247 247 SER SER C . n 
C 2 273 ALA 273 248 248 ALA ALA C . n 
C 2 274 ALA 274 249 249 ALA ALA C . n 
C 2 275 ARG 275 250 250 ARG ARG C . n 
C 2 276 VAL 276 251 251 VAL VAL C . n 
C 2 277 ALA 277 252 252 ALA ALA C . n 
C 2 278 LEU 278 253 253 LEU LEU C . n 
C 2 279 GLY 279 254 254 GLY GLY C . n 
C 2 280 ILE 280 255 255 ILE ILE C . n 
C 2 281 THR 281 256 256 THR THR C . n 
C 2 282 THR 282 257 257 THR THR C . n 
C 2 283 VAL 283 258 258 VAL VAL C . n 
C 2 284 LEU 284 259 259 LEU LEU C . n 
C 2 285 THR 285 260 260 THR THR C . n 
C 2 286 MET 286 261 261 MET MET C . n 
C 2 287 THR 287 262 262 THR THR C . n 
C 2 288 THR 288 263 263 THR THR C . n 
C 2 289 ILE 289 264 264 ILE ILE C . n 
C 2 290 ASN 290 265 265 ASN ASN C . n 
C 2 291 THR 291 266 266 THR THR C . n 
C 2 292 HIS 292 267 267 HIS HIS C . n 
C 2 293 LEU 293 268 268 LEU LEU C . n 
C 2 294 ARG 294 269 269 ARG ARG C . n 
C 2 295 GLU 295 270 270 GLU GLU C . n 
C 2 296 THR 296 271 271 THR THR C . n 
C 2 297 LEU 297 272 272 LEU LEU C . n 
C 2 298 PRO 298 273 273 PRO PRO C . n 
C 2 299 LYS 299 274 274 LYS LYS C . n 
C 2 300 ILE 300 275 275 ILE ILE C . n 
C 2 301 PRO 301 276 276 PRO PRO C . n 
C 2 302 TYR 302 277 277 TYR TYR C . n 
C 2 303 VAL 303 278 278 VAL VAL C . n 
C 2 304 LYS 304 279 279 LYS LYS C . n 
C 2 305 ALA 305 280 280 ALA ALA C . n 
C 2 306 ILE 306 281 281 ILE ILE C . n 
C 2 307 ASP 307 282 282 ASP ASP C . n 
C 2 308 MET 308 283 283 MET MET C . n 
C 2 309 TYR 309 284 284 TYR TYR C . n 
C 2 310 LEU 310 285 285 LEU LEU C . n 
C 2 311 MET 311 286 286 MET MET C . n 
C 2 312 GLY 312 287 287 GLY GLY C . n 
C 2 313 CYS 313 288 288 CYS CYS C . n 
C 2 314 PHE 314 289 289 PHE PHE C . n 
C 2 315 VAL 315 290 290 VAL VAL C . n 
C 2 316 PHE 316 291 291 PHE PHE C . n 
C 2 317 VAL 317 292 292 VAL VAL C . n 
C 2 318 PHE 318 293 293 PHE PHE C . n 
C 2 319 LEU 319 294 294 LEU LEU C . n 
C 2 320 ALA 320 295 295 ALA ALA C . n 
C 2 321 LEU 321 296 296 LEU LEU C . n 
C 2 322 LEU 322 297 297 LEU LEU C . n 
C 2 323 GLU 323 298 298 GLU GLU C . n 
C 2 324 TYR 324 299 299 TYR TYR C . n 
C 2 325 ALA 325 300 300 ALA ALA C . n 
C 2 326 PHE 326 301 301 PHE PHE C . n 
C 2 327 VAL 327 302 302 VAL VAL C . n 
C 2 328 ASN 328 303 303 ASN ASN C . n 
C 2 329 TYR 329 304 304 TYR TYR C . n 
C 2 330 ILE 330 305 305 ILE ILE C . n 
C 2 331 PHE 331 306 306 PHE PHE C . n 
C 2 332 PHE 332 307 307 PHE PHE C . n 
C 2 333 GLY 333 308 308 GLY GLY C . n 
C 2 334 ARG 334 309 309 ARG ARG C . n 
C 2 335 GLY 335 335 ?   ?   ?   C . n 
C 2 336 PRO 336 336 ?   ?   ?   C . n 
C 2 337 GLN 337 337 ?   ?   ?   C . n 
C 2 338 ARG 338 338 ?   ?   ?   C . n 
C 2 339 GLN 339 339 ?   ?   ?   C . n 
C 2 340 LYS 340 340 ?   ?   ?   C . n 
C 2 341 LYS 341 341 ?   ?   ?   C . n 
C 2 342 LEU 342 342 ?   ?   ?   C . n 
C 2 343 ALA 343 343 ?   ?   ?   C . n 
C 2 344 GLU 344 344 ?   ?   ?   C . n 
C 2 345 LYS 345 345 ?   ?   ?   C . n 
C 2 346 THR 346 346 ?   ?   ?   C . n 
C 2 347 ALA 347 347 ?   ?   ?   C . n 
C 2 348 LYS 348 348 ?   ?   ?   C . n 
C 2 349 ALA 349 349 ?   ?   ?   C . n 
C 2 350 LYS 350 350 ?   ?   ?   C . n 
C 2 351 ASN 351 351 ?   ?   ?   C . n 
C 2 352 ASP 352 352 ?   ?   ?   C . n 
C 2 353 ARG 353 353 ?   ?   ?   C . n 
C 2 354 SER 354 354 ?   ?   ?   C . n 
C 2 355 LYS 355 355 ?   ?   ?   C . n 
C 2 356 SER 356 356 ?   ?   ?   C . n 
C 2 357 GLU 357 357 ?   ?   ?   C . n 
C 2 358 SER 358 358 ?   ?   ?   C . n 
C 2 359 ASN 359 359 ?   ?   ?   C . n 
C 2 360 ARG 360 360 ?   ?   ?   C . n 
C 2 361 VAL 361 361 ?   ?   ?   C . n 
C 2 362 ASP 362 362 ?   ?   ?   C . n 
C 2 363 ALA 363 363 ?   ?   ?   C . n 
C 2 364 HIS 364 364 ?   ?   ?   C . n 
C 2 365 GLY 365 365 ?   ?   ?   C . n 
C 2 366 ASN 366 366 ?   ?   ?   C . n 
C 2 367 ILE 367 367 ?   ?   ?   C . n 
C 2 368 LEU 368 368 ?   ?   ?   C . n 
C 2 369 LEU 369 369 ?   ?   ?   C . n 
C 2 370 THR 370 370 ?   ?   ?   C . n 
C 2 371 SER 371 371 ?   ?   ?   C . n 
C 2 372 LEU 372 372 ?   ?   ?   C . n 
C 2 373 GLU 373 373 ?   ?   ?   C . n 
C 2 374 VAL 374 374 ?   ?   ?   C . n 
C 2 375 HIS 375 375 ?   ?   ?   C . n 
C 2 376 ASN 376 376 ?   ?   ?   C . n 
C 2 377 GLU 377 377 ?   ?   ?   C . n 
C 2 378 MET 378 378 ?   ?   ?   C . n 
C 2 379 ASN 379 379 ?   ?   ?   C . n 
C 2 380 GLU 380 380 ?   ?   ?   C . n 
C 2 381 VAL 381 381 ?   ?   ?   C . n 
C 2 382 SER 382 382 ?   ?   ?   C . n 
C 2 383 GLY 383 383 ?   ?   ?   C . n 
C 2 384 GLY 384 384 ?   ?   ?   C . n 
C 2 385 ILE 385 385 ?   ?   ?   C . n 
C 2 386 GLY 386 386 ?   ?   ?   C . n 
C 2 387 ASP 387 387 ?   ?   ?   C . n 
C 2 388 THR 388 388 ?   ?   ?   C . n 
C 2 389 ARG 389 389 ?   ?   ?   C . n 
C 2 390 ASN 390 390 ?   ?   ?   C . n 
C 2 391 SER 391 391 ?   ?   ?   C . n 
C 2 392 ALA 392 392 ?   ?   ?   C . n 
C 2 393 ILE 393 393 ?   ?   ?   C . n 
C 2 394 SER 394 394 ?   ?   ?   C . n 
C 2 395 PHE 395 395 ?   ?   ?   C . n 
C 2 396 ASP 396 396 ?   ?   ?   C . n 
C 2 397 ASN 397 397 ?   ?   ?   C . n 
C 2 398 SER 398 398 ?   ?   ?   C . n 
C 2 399 GLY 399 399 ?   ?   ?   C . n 
C 2 400 ILE 400 400 ?   ?   ?   C . n 
C 2 401 GLN 401 401 ?   ?   ?   C . n 
C 2 402 TYR 402 402 ?   ?   ?   C . n 
C 2 403 ARG 403 403 ?   ?   ?   C . n 
C 2 404 LYS 404 404 ?   ?   ?   C . n 
C 2 405 GLN 405 405 ?   ?   ?   C . n 
C 2 406 SER 406 406 ?   ?   ?   C . n 
C 2 407 MET 407 407 ?   ?   ?   C . n 
C 2 408 PRO 408 408 ?   ?   ?   C . n 
C 2 409 ARG 409 409 ?   ?   ?   C . n 
C 2 410 GLU 410 410 ?   ?   ?   C . n 
C 2 411 GLY 411 411 ?   ?   ?   C . n 
C 2 412 HIS 412 412 ?   ?   ?   C . n 
C 2 413 GLY 413 413 ?   ?   ?   C . n 
C 2 414 ARG 414 414 ?   ?   ?   C . n 
C 2 415 PHE 415 415 ?   ?   ?   C . n 
C 2 416 LEU 416 416 ?   ?   ?   C . n 
C 2 417 GLY 417 417 ?   ?   ?   C . n 
C 2 418 ASP 418 418 ?   ?   ?   C . n 
C 2 419 ARG 419 419 ?   ?   ?   C . n 
C 2 420 SER 420 420 ?   ?   ?   C . n 
C 2 421 LEU 421 421 ?   ?   ?   C . n 
C 2 422 PRO 422 422 ?   ?   ?   C . n 
C 2 423 HIS 423 423 ?   ?   ?   C . n 
C 2 424 LYS 424 424 ?   ?   ?   C . n 
C 2 425 LYS 425 425 ?   ?   ?   C . n 
C 2 426 THR 426 426 ?   ?   ?   C . n 
C 2 427 HIS 427 427 ?   ?   ?   C . n 
C 2 428 LEU 428 428 ?   ?   ?   C . n 
C 2 429 ARG 429 429 ?   ?   ?   C . n 
C 2 430 ARG 430 430 ?   ?   ?   C . n 
C 2 431 ARG 431 431 ?   ?   ?   C . n 
C 2 432 SER 432 432 ?   ?   ?   C . n 
C 2 433 SER 433 433 ?   ?   ?   C . n 
C 2 434 GLN 434 434 ?   ?   ?   C . n 
C 2 435 LEU 435 435 ?   ?   ?   C . n 
C 2 436 LYS 436 436 ?   ?   ?   C . n 
C 2 437 ILE 437 437 ?   ?   ?   C . n 
C 2 438 LYS 438 438 ?   ?   ?   C . n 
C 2 439 ILE 439 439 ?   ?   ?   C . n 
C 2 440 PRO 440 440 ?   ?   ?   C . n 
C 2 441 ASP 441 441 ?   ?   ?   C . n 
C 2 442 LEU 442 442 ?   ?   ?   C . n 
C 2 443 THR 443 443 ?   ?   ?   C . n 
C 2 444 ASP 444 444 444 ASP ASP C . n 
C 2 445 VAL 445 445 445 VAL VAL C . n 
C 2 446 ASN 446 446 446 ASN ASN C . n 
C 2 447 ALA 447 447 447 ALA ALA C . n 
C 2 448 ILE 448 448 448 ILE ILE C . n 
C 2 449 ASP 449 449 449 ASP ASP C . n 
C 2 450 ARG 450 450 450 ARG ARG C . n 
C 2 451 TRP 451 451 451 TRP TRP C . n 
C 2 452 SER 452 452 452 SER SER C . n 
C 2 453 ARG 453 453 453 ARG ARG C . n 
C 2 454 ILE 454 454 454 ILE ILE C . n 
C 2 455 VAL 455 455 455 VAL VAL C . n 
C 2 456 PHE 456 456 456 PHE PHE C . n 
C 2 457 PRO 457 457 457 PRO PRO C . n 
C 2 458 PHE 458 458 458 PHE PHE C . n 
C 2 459 THR 459 459 459 THR THR C . n 
C 2 460 PHE 460 460 460 PHE PHE C . n 
C 2 461 SER 461 461 461 SER SER C . n 
C 2 462 LEU 462 462 462 LEU LEU C . n 
C 2 463 PHE 463 463 463 PHE PHE C . n 
C 2 464 ASN 464 464 464 ASN ASN C . n 
C 2 465 LEU 465 465 465 LEU LEU C . n 
C 2 466 VAL 466 466 466 VAL VAL C . n 
C 2 467 TYR 467 467 467 TYR TYR C . n 
C 2 468 TRP 468 468 468 TRP TRP C . n 
C 2 469 LEU 469 469 469 LEU LEU C . n 
C 2 470 TYR 470 470 470 TYR TYR C . n 
C 2 471 TYR 471 471 471 TYR TYR C . n 
C 2 472 VAL 472 472 472 VAL VAL C . n 
C 2 473 ASN 473 473 ?   ?   ?   C . n 
D 1 1   MET 1   -34 ?   ?   ?   D . n 
D 1 2   LYS 2   -33 ?   ?   ?   D . n 
D 1 3   LYS 3   -32 ?   ?   ?   D . n 
D 1 4   SER 4   -31 ?   ?   ?   D . n 
D 1 5   PRO 5   -30 ?   ?   ?   D . n 
D 1 6   GLY 6   -29 ?   ?   ?   D . n 
D 1 7   LEU 7   -28 ?   ?   ?   D . n 
D 1 8   SER 8   -27 ?   ?   ?   D . n 
D 1 9   ASP 9   -26 ?   ?   ?   D . n 
D 1 10  TYR 10  -25 ?   ?   ?   D . n 
D 1 11  LEU 11  -24 ?   ?   ?   D . n 
D 1 12  TRP 12  -23 ?   ?   ?   D . n 
D 1 13  ALA 13  -22 ?   ?   ?   D . n 
D 1 14  TRP 14  -21 ?   ?   ?   D . n 
D 1 15  THR 15  -20 ?   ?   ?   D . n 
D 1 16  LEU 16  -19 ?   ?   ?   D . n 
D 1 17  PHE 17  -18 ?   ?   ?   D . n 
D 1 18  LEU 18  -17 ?   ?   ?   D . n 
D 1 19  SER 19  -16 ?   ?   ?   D . n 
D 1 20  THR 20  -15 ?   ?   ?   D . n 
D 1 21  LEU 21  -14 ?   ?   ?   D . n 
D 1 22  THR 22  -13 ?   ?   ?   D . n 
D 1 23  GLY 23  -12 ?   ?   ?   D . n 
D 1 24  ARG 24  -11 ?   ?   ?   D . n 
D 1 25  SER 25  -10 ?   ?   ?   D . n 
D 1 26  TYR 26  -9  ?   ?   ?   D . n 
D 1 27  GLY 27  -8  ?   ?   ?   D . n 
D 1 28  ASP 28  -7  ?   ?   ?   D . n 
D 1 29  TYR 29  -6  ?   ?   ?   D . n 
D 1 30  LYS 30  -5  ?   ?   ?   D . n 
D 1 31  ASP 31  -4  ?   ?   ?   D . n 
D 1 32  ASP 32  -3  ?   ?   ?   D . n 
D 1 33  ASP 33  -2  ?   ?   ?   D . n 
D 1 34  ASP 34  -1  ?   ?   ?   D . n 
D 1 35  LYS 35  0   ?   ?   ?   D . n 
D 1 36  GLN 36  1   ?   ?   ?   D . n 
D 1 37  PRO 37  2   ?   ?   ?   D . n 
D 1 38  SER 38  3   ?   ?   ?   D . n 
D 1 39  LEU 39  4   ?   ?   ?   D . n 
D 1 40  GLN 40  5   ?   ?   ?   D . n 
D 1 41  ASP 41  6   ?   ?   ?   D . n 
D 1 42  GLU 42  7   ?   ?   ?   D . n 
D 1 43  LEU 43  8   ?   ?   ?   D . n 
D 1 44  LYS 44  9   ?   ?   ?   D . n 
D 1 45  ASP 45  10  ?   ?   ?   D . n 
D 1 46  ASN 46  11  ?   ?   ?   D . n 
D 1 47  THR 47  12  12  THR THR D . n 
D 1 48  THR 48  13  13  THR THR D . n 
D 1 49  VAL 49  14  14  VAL VAL D . n 
D 1 50  PHE 50  15  15  PHE PHE D . n 
D 1 51  THR 51  16  16  THR THR D . n 
D 1 52  ARG 52  17  17  ARG ARG D . n 
D 1 53  ILE 53  18  18  ILE ILE D . n 
D 1 54  LEU 54  19  19  LEU LEU D . n 
D 1 55  ASP 55  20  20  ASP ASP D . n 
D 1 56  ARG 56  21  21  ARG ARG D . n 
D 1 57  LEU 57  22  22  LEU LEU D . n 
D 1 58  LEU 58  23  23  LEU LEU D . n 
D 1 59  ASP 59  24  24  ASP ASP D . n 
D 1 60  GLY 60  25  25  GLY GLY D . n 
D 1 61  TYR 61  26  26  TYR TYR D . n 
D 1 62  ASP 62  27  27  ASP ASP D . n 
D 1 63  ASN 63  28  28  ASN ASN D . n 
D 1 64  ARG 64  29  29  ARG ARG D . n 
D 1 65  LEU 65  30  30  LEU LEU D . n 
D 1 66  ARG 66  31  31  ARG ARG D . n 
D 1 67  PRO 67  32  32  PRO PRO D . n 
D 1 68  GLY 68  33  33  GLY GLY D . n 
D 1 69  LEU 69  34  34  LEU LEU D . n 
D 1 70  GLY 70  35  35  GLY GLY D . n 
D 1 71  GLU 71  36  36  GLU GLU D . n 
D 1 72  ARG 72  37  37  ARG ARG D . n 
D 1 73  VAL 73  38  38  VAL VAL D . n 
D 1 74  THR 74  39  39  THR THR D . n 
D 1 75  GLU 75  40  40  GLU GLU D . n 
D 1 76  VAL 76  41  41  VAL VAL D . n 
D 1 77  LYS 77  42  42  LYS LYS D . n 
D 1 78  THR 78  43  43  THR THR D . n 
D 1 79  ASP 79  44  44  ASP ASP D . n 
D 1 80  ILE 80  45  45  ILE ILE D . n 
D 1 81  PHE 81  46  46  PHE PHE D . n 
D 1 82  VAL 82  47  47  VAL VAL D . n 
D 1 83  THR 83  48  48  THR THR D . n 
D 1 84  SER 84  49  49  SER SER D . n 
D 1 85  PHE 85  50  50  PHE PHE D . n 
D 1 86  GLY 86  51  51  GLY GLY D . n 
D 1 87  PRO 87  52  52  PRO PRO D . n 
D 1 88  VAL 88  53  53  VAL VAL D . n 
D 1 89  SER 89  54  54  SER SER D . n 
D 1 90  ASP 90  55  55  ASP ASP D . n 
D 1 91  HIS 91  56  56  HIS HIS D . n 
D 1 92  ASP 92  57  57  ASP ASP D . n 
D 1 93  MET 93  58  58  MET MET D . n 
D 1 94  GLU 94  59  59  GLU GLU D . n 
D 1 95  TYR 95  60  60  TYR TYR D . n 
D 1 96  THR 96  61  61  THR THR D . n 
D 1 97  ILE 97  62  62  ILE ILE D . n 
D 1 98  ASP 98  63  63  ASP ASP D . n 
D 1 99  VAL 99  64  64  VAL VAL D . n 
D 1 100 PHE 100 65  65  PHE PHE D . n 
D 1 101 PHE 101 66  66  PHE PHE D . n 
D 1 102 ARG 102 67  67  ARG ARG D . n 
D 1 103 GLN 103 68  68  GLN GLN D . n 
D 1 104 SER 104 69  69  SER SER D . n 
D 1 105 TRP 105 70  70  TRP TRP D . n 
D 1 106 LYS 106 71  71  LYS LYS D . n 
D 1 107 ASP 107 72  72  ASP ASP D . n 
D 1 108 GLU 108 73  73  GLU GLU D . n 
D 1 109 ARG 109 74  74  ARG ARG D . n 
D 1 110 LEU 110 75  75  LEU LEU D . n 
D 1 111 LYS 111 76  76  LYS LYS D . n 
D 1 112 PHE 112 77  77  PHE PHE D . n 
D 1 113 LYS 113 78  78  LYS LYS D . n 
D 1 114 GLY 114 79  79  GLY GLY D . n 
D 1 115 PRO 115 80  80  PRO PRO D . n 
D 1 116 MET 116 81  81  MET MET D . n 
D 1 117 THR 117 82  82  THR THR D . n 
D 1 118 VAL 118 83  83  VAL VAL D . n 
D 1 119 LEU 119 84  84  LEU LEU D . n 
D 1 120 ARG 120 85  85  ARG ARG D . n 
D 1 121 LEU 121 86  86  LEU LEU D . n 
D 1 122 ASN 122 87  87  ASN ASN D . n 
D 1 123 ASN 123 88  88  ASN ASN D . n 
D 1 124 LEU 124 89  89  LEU LEU D . n 
D 1 125 MET 125 90  90  MET MET D . n 
D 1 126 ALA 126 91  91  ALA ALA D . n 
D 1 127 SER 127 92  92  SER SER D . n 
D 1 128 LYS 128 93  93  LYS LYS D . n 
D 1 129 ILE 129 94  94  ILE ILE D . n 
D 1 130 TRP 130 95  95  TRP TRP D . n 
D 1 131 THR 131 96  96  THR THR D . n 
D 1 132 PRO 132 97  97  PRO PRO D . n 
D 1 133 ASP 133 98  98  ASP ASP D . n 
D 1 134 THR 134 99  99  THR THR D . n 
D 1 135 PHE 135 100 100 PHE PHE D . n 
D 1 136 PHE 136 101 101 PHE PHE D . n 
D 1 137 HIS 137 102 102 HIS HIS D . n 
D 1 138 ASN 138 103 103 ASN ASN D . n 
D 1 139 GLY 139 104 104 GLY GLY D . n 
D 1 140 LYS 140 105 105 LYS LYS D . n 
D 1 141 LYS 141 106 106 LYS LYS D . n 
D 1 142 SER 142 107 107 SER SER D . n 
D 1 143 VAL 143 108 108 VAL VAL D . n 
D 1 144 ALA 144 109 109 ALA ALA D . n 
D 1 145 HIS 145 110 110 HIS HIS D . n 
D 1 146 ASN 146 111 111 ASN ASN D . n 
D 1 147 MET 147 112 112 MET MET D . n 
D 1 148 THR 148 113 113 THR THR D . n 
D 1 149 MET 149 114 114 MET MET D . n 
D 1 150 PRO 150 115 115 PRO PRO D . n 
D 1 151 ASN 151 116 116 ASN ASN D . n 
D 1 152 LYS 152 117 117 LYS LYS D . n 
D 1 153 LEU 153 118 118 LEU LEU D . n 
D 1 154 LEU 154 119 119 LEU LEU D . n 
D 1 155 ARG 155 120 120 ARG ARG D . n 
D 1 156 ILE 156 121 121 ILE ILE D . n 
D 1 157 THR 157 122 122 THR THR D . n 
D 1 158 GLU 158 123 123 GLU GLU D . n 
D 1 159 ASP 159 124 124 ASP ASP D . n 
D 1 160 GLY 160 125 125 GLY GLY D . n 
D 1 161 THR 161 126 126 THR THR D . n 
D 1 162 LEU 162 127 127 LEU LEU D . n 
D 1 163 LEU 163 128 128 LEU LEU D . n 
D 1 164 TYR 164 129 129 TYR TYR D . n 
D 1 165 THR 165 130 130 THR THR D . n 
D 1 166 MET 166 131 131 MET MET D . n 
D 1 167 ARG 167 132 132 ARG ARG D . n 
D 1 168 LEU 168 133 133 LEU LEU D . n 
D 1 169 THR 169 134 134 THR THR D . n 
D 1 170 VAL 170 135 135 VAL VAL D . n 
D 1 171 ARG 171 136 136 ARG ARG D . n 
D 1 172 ALA 172 137 137 ALA ALA D . n 
D 1 173 GLU 173 138 138 GLU GLU D . n 
D 1 174 CYS 174 139 139 CYS CYS D . n 
D 1 175 PRO 175 140 140 PRO PRO D . n 
D 1 176 MET 176 141 141 MET MET D . n 
D 1 177 HIS 177 142 142 HIS HIS D . n 
D 1 178 LEU 178 143 143 LEU LEU D . n 
D 1 179 GLU 179 144 144 GLU GLU D . n 
D 1 180 ASP 180 145 145 ASP ASP D . n 
D 1 181 PHE 181 146 146 PHE PHE D . n 
D 1 182 PRO 182 147 147 PRO PRO D . n 
D 1 183 MET 183 148 148 MET MET D . n 
D 1 184 ASP 184 149 149 ASP ASP D . n 
D 1 185 ALA 185 150 150 ALA ALA D . n 
D 1 186 HIS 186 151 151 HIS HIS D . n 
D 1 187 ALA 187 152 152 ALA ALA D . n 
D 1 188 CYS 188 153 153 CYS CYS D . n 
D 1 189 PRO 189 154 154 PRO PRO D . n 
D 1 190 LEU 190 155 155 LEU LEU D . n 
D 1 191 LYS 191 156 156 LYS LYS D . n 
D 1 192 PHE 192 157 157 PHE PHE D . n 
D 1 193 GLY 193 158 158 GLY GLY D . n 
D 1 194 SER 194 159 159 SER SER D . n 
D 1 195 TYR 195 160 160 TYR TYR D . n 
D 1 196 ALA 196 161 161 ALA ALA D . n 
D 1 197 TYR 197 162 162 TYR TYR D . n 
D 1 198 THR 198 163 163 THR THR D . n 
D 1 199 ARG 199 164 164 ARG ARG D . n 
D 1 200 ALA 200 165 165 ALA ALA D . n 
D 1 201 GLU 201 166 166 GLU GLU D . n 
D 1 202 VAL 202 167 167 VAL VAL D . n 
D 1 203 VAL 203 168 168 VAL VAL D . n 
D 1 204 TYR 204 169 169 TYR TYR D . n 
D 1 205 GLU 205 170 170 GLU GLU D . n 
D 1 206 TRP 206 171 171 TRP TRP D . n 
D 1 207 THR 207 172 172 THR THR D . n 
D 1 208 ARG 208 173 173 ARG ARG D . n 
D 1 209 GLU 209 174 174 GLU GLU D . n 
D 1 210 PRO 210 175 175 PRO PRO D . n 
D 1 211 ALA 211 176 176 ALA ALA D . n 
D 1 212 ARG 212 177 177 ARG ARG D . n 
D 1 213 SER 213 178 178 SER SER D . n 
D 1 214 VAL 214 179 179 VAL VAL D . n 
D 1 215 VAL 215 180 180 VAL VAL D . n 
D 1 216 VAL 216 181 181 VAL VAL D . n 
D 1 217 ALA 217 182 182 ALA ALA D . n 
D 1 218 GLU 218 183 183 GLU GLU D . n 
D 1 219 ASP 219 184 184 ASP ASP D . n 
D 1 220 GLY 220 185 185 GLY GLY D . n 
D 1 221 SER 221 186 186 SER SER D . n 
D 1 222 ARG 222 187 187 ARG ARG D . n 
D 1 223 LEU 223 188 188 LEU LEU D . n 
D 1 224 ASN 224 189 189 ASN ASN D . n 
D 1 225 GLN 225 190 190 GLN GLN D . n 
D 1 226 TYR 226 191 191 TYR TYR D . n 
D 1 227 ASP 227 192 192 ASP ASP D . n 
D 1 228 LEU 228 193 193 LEU LEU D . n 
D 1 229 LEU 229 194 194 LEU LEU D . n 
D 1 230 GLY 230 195 195 GLY GLY D . n 
D 1 231 GLN 231 196 196 GLN GLN D . n 
D 1 232 THR 232 197 197 THR THR D . n 
D 1 233 VAL 233 198 198 VAL VAL D . n 
D 1 234 ASP 234 199 199 ASP ASP D . n 
D 1 235 SER 235 200 200 SER SER D . n 
D 1 236 GLY 236 201 201 GLY GLY D . n 
D 1 237 ILE 237 202 202 ILE ILE D . n 
D 1 238 VAL 238 203 203 VAL VAL D . n 
D 1 239 GLN 239 204 204 GLN GLN D . n 
D 1 240 SER 240 205 205 SER SER D . n 
D 1 241 SER 241 206 206 SER SER D . n 
D 1 242 THR 242 207 207 THR THR D . n 
D 1 243 GLY 243 208 208 GLY GLY D . n 
D 1 244 GLU 244 209 209 GLU GLU D . n 
D 1 245 TYR 245 210 210 TYR TYR D . n 
D 1 246 VAL 246 211 211 VAL VAL D . n 
D 1 247 VAL 247 212 212 VAL VAL D . n 
D 1 248 MET 248 213 213 MET MET D . n 
D 1 249 THR 249 214 214 THR THR D . n 
D 1 250 THR 250 215 215 THR THR D . n 
D 1 251 HIS 251 216 216 HIS HIS D . n 
D 1 252 PHE 252 217 217 PHE PHE D . n 
D 1 253 HIS 253 218 218 HIS HIS D . n 
D 1 254 LEU 254 219 219 LEU LEU D . n 
D 1 255 LYS 255 220 220 LYS LYS D . n 
D 1 256 ARG 256 221 221 ARG ARG D . n 
D 1 257 LYS 257 222 222 LYS LYS D . n 
D 1 258 ILE 258 223 223 ILE ILE D . n 
D 1 259 GLY 259 224 224 GLY GLY D . n 
D 1 260 TYR 260 225 225 TYR TYR D . n 
D 1 261 PHE 261 226 226 PHE PHE D . n 
D 1 262 VAL 262 227 227 VAL VAL D . n 
D 1 263 ILE 263 228 228 ILE ILE D . n 
D 1 264 GLN 264 229 229 GLN GLN D . n 
D 1 265 THR 265 230 230 THR THR D . n 
D 1 266 TYR 266 231 231 TYR TYR D . n 
D 1 267 LEU 267 232 232 LEU LEU D . n 
D 1 268 PRO 268 233 233 PRO PRO D . n 
D 1 269 CYS 269 234 234 CYS CYS D . n 
D 1 270 ILE 270 235 235 ILE ILE D . n 
D 1 271 MET 271 236 236 MET MET D . n 
D 1 272 THR 272 237 237 THR THR D . n 
D 1 273 VAL 273 238 238 VAL VAL D . n 
D 1 274 ILE 274 239 239 ILE ILE D . n 
D 1 275 LEU 275 240 240 LEU LEU D . n 
D 1 276 SER 276 241 241 SER SER D . n 
D 1 277 GLN 277 242 242 GLN GLN D . n 
D 1 278 VAL 278 243 243 VAL VAL D . n 
D 1 279 SER 279 244 244 SER SER D . n 
D 1 280 PHE 280 245 245 PHE PHE D . n 
D 1 281 TRP 281 246 246 TRP TRP D . n 
D 1 282 LEU 282 247 247 LEU LEU D . n 
D 1 283 ASN 283 248 248 ASN ASN D . n 
D 1 284 ARG 284 249 249 ARG ARG D . n 
D 1 285 GLU 285 250 250 GLU GLU D . n 
D 1 286 SER 286 251 251 SER SER D . n 
D 1 287 VAL 287 252 252 VAL VAL D . n 
D 1 288 PRO 288 253 253 PRO PRO D . n 
D 1 289 ALA 289 254 254 ALA ALA D . n 
D 1 290 ARG 290 255 255 ARG ARG D . n 
D 1 291 THR 291 256 256 THR THR D . n 
D 1 292 VAL 292 257 257 VAL VAL D . n 
D 1 293 PHE 293 258 258 PHE PHE D . n 
D 1 294 GLY 294 259 259 GLY GLY D . n 
D 1 295 VAL 295 260 260 VAL VAL D . n 
D 1 296 THR 296 261 261 THR THR D . n 
D 1 297 THR 297 262 262 THR THR D . n 
D 1 298 VAL 298 263 263 VAL VAL D . n 
D 1 299 LEU 299 264 264 LEU LEU D . n 
D 1 300 THR 300 265 265 THR THR D . n 
D 1 301 MET 301 266 266 MET MET D . n 
D 1 302 THR 302 267 267 THR THR D . n 
D 1 303 THR 303 268 268 THR THR D . n 
D 1 304 LEU 304 269 269 LEU LEU D . n 
D 1 305 SER 305 270 270 SER SER D . n 
D 1 306 ILE 306 271 271 ILE ILE D . n 
D 1 307 SER 307 272 272 SER SER D . n 
D 1 308 ALA 308 273 273 ALA ALA D . n 
D 1 309 ARG 309 274 274 ARG ARG D . n 
D 1 310 ASN 310 275 275 ASN ASN D . n 
D 1 311 SER 311 276 276 SER SER D . n 
D 1 312 LEU 312 277 277 LEU LEU D . n 
D 1 313 PRO 313 278 278 PRO PRO D . n 
D 1 314 LYS 314 279 279 LYS LYS D . n 
D 1 315 VAL 315 280 280 VAL VAL D . n 
D 1 316 ALA 316 281 281 ALA ALA D . n 
D 1 317 TYR 317 282 282 TYR TYR D . n 
D 1 318 ALA 318 283 283 ALA ALA D . n 
D 1 319 THR 319 284 284 THR THR D . n 
D 1 320 ALA 320 285 285 ALA ALA D . n 
D 1 321 MET 321 286 286 MET MET D . n 
D 1 322 ASP 322 287 287 ASP ASP D . n 
D 1 323 TRP 323 288 288 TRP TRP D . n 
D 1 324 PHE 324 289 289 PHE PHE D . n 
D 1 325 ILE 325 290 290 ILE ILE D . n 
D 1 326 ALA 326 291 291 ALA ALA D . n 
D 1 327 VAL 327 292 292 VAL VAL D . n 
D 1 328 CYS 328 293 293 CYS CYS D . n 
D 1 329 TYR 329 294 294 TYR TYR D . n 
D 1 330 ALA 330 295 295 ALA ALA D . n 
D 1 331 PHE 331 296 296 PHE PHE D . n 
D 1 332 VAL 332 297 297 VAL VAL D . n 
D 1 333 PHE 333 298 298 PHE PHE D . n 
D 1 334 SER 334 299 299 SER SER D . n 
D 1 335 ALA 335 300 300 ALA ALA D . n 
D 1 336 LEU 336 301 301 LEU LEU D . n 
D 1 337 ILE 337 302 302 ILE ILE D . n 
D 1 338 GLU 338 303 303 GLU GLU D . n 
D 1 339 PHE 339 304 304 PHE PHE D . n 
D 1 340 ALA 340 305 305 ALA ALA D . n 
D 1 341 THR 341 306 306 THR THR D . n 
D 1 342 VAL 342 307 307 VAL VAL D . n 
D 1 343 ASN 343 308 308 ASN ASN D . n 
D 1 344 TYR 344 309 309 TYR TYR D . n 
D 1 345 PHE 345 310 310 PHE PHE D . n 
D 1 346 THR 346 311 311 THR THR D . n 
D 1 347 LYS 347 312 312 LYS LYS D . n 
D 1 348 ARG 348 313 313 ARG ARG D . n 
D 1 349 GLY 349 314 314 GLY GLY D . n 
D 1 350 TYR 350 315 315 TYR TYR D . n 
D 1 351 ALA 351 316 316 ALA ALA D . n 
D 1 352 TRP 352 317 317 TRP TRP D . n 
D 1 353 ASP 353 318 318 ASP ASP D . n 
D 1 354 GLY 354 319 319 GLY GLY D . n 
D 1 355 LYS 355 320 320 LYS LYS D . n 
D 1 356 SER 356 321 321 SER SER D . n 
D 1 357 VAL 357 322 ?   ?   ?   D . n 
D 1 358 VAL 358 323 ?   ?   ?   D . n 
D 1 359 PRO 359 324 ?   ?   ?   D . n 
D 1 360 GLU 360 325 ?   ?   ?   D . n 
D 1 361 LYS 361 326 ?   ?   ?   D . n 
D 1 362 PRO 362 327 ?   ?   ?   D . n 
D 1 363 LYS 363 328 ?   ?   ?   D . n 
D 1 364 LYS 364 329 ?   ?   ?   D . n 
D 1 365 VAL 365 330 ?   ?   ?   D . n 
D 1 366 LYS 366 331 ?   ?   ?   D . n 
D 1 367 ASP 367 332 ?   ?   ?   D . n 
D 1 368 PRO 368 333 ?   ?   ?   D . n 
D 1 369 LEU 369 334 ?   ?   ?   D . n 
D 1 370 ILE 370 335 ?   ?   ?   D . n 
D 1 371 LYS 371 336 ?   ?   ?   D . n 
D 1 372 LYS 372 337 ?   ?   ?   D . n 
D 1 373 ASN 373 338 ?   ?   ?   D . n 
D 1 374 ASN 374 339 ?   ?   ?   D . n 
D 1 375 THR 375 340 ?   ?   ?   D . n 
D 1 376 TYR 376 341 ?   ?   ?   D . n 
D 1 377 ALA 377 342 ?   ?   ?   D . n 
D 1 378 PRO 378 343 ?   ?   ?   D . n 
D 1 379 THR 379 344 ?   ?   ?   D . n 
D 1 380 ALA 380 345 ?   ?   ?   D . n 
D 1 381 THR 381 346 ?   ?   ?   D . n 
D 1 382 SER 382 347 ?   ?   ?   D . n 
D 1 383 TYR 383 348 ?   ?   ?   D . n 
D 1 384 THR 384 349 ?   ?   ?   D . n 
D 1 385 PRO 385 350 ?   ?   ?   D . n 
D 1 386 ASN 386 351 ?   ?   ?   D . n 
D 1 387 LEU 387 352 ?   ?   ?   D . n 
D 1 388 ALA 388 353 ?   ?   ?   D . n 
D 1 389 ARG 389 354 ?   ?   ?   D . n 
D 1 390 GLY 390 355 ?   ?   ?   D . n 
D 1 391 ASP 391 356 ?   ?   ?   D . n 
D 1 392 PRO 392 357 ?   ?   ?   D . n 
D 1 393 GLY 393 358 ?   ?   ?   D . n 
D 1 394 LEU 394 359 ?   ?   ?   D . n 
D 1 395 ALA 395 360 ?   ?   ?   D . n 
D 1 396 THR 396 361 ?   ?   ?   D . n 
D 1 397 ILE 397 362 ?   ?   ?   D . n 
D 1 398 ALA 398 363 ?   ?   ?   D . n 
D 1 399 LYS 399 364 ?   ?   ?   D . n 
D 1 400 SER 400 365 ?   ?   ?   D . n 
D 1 401 ALA 401 366 ?   ?   ?   D . n 
D 1 402 THR 402 367 ?   ?   ?   D . n 
D 1 403 ILE 403 368 ?   ?   ?   D . n 
D 1 404 GLU 404 369 ?   ?   ?   D . n 
D 1 405 PRO 405 370 ?   ?   ?   D . n 
D 1 406 LYS 406 371 ?   ?   ?   D . n 
D 1 407 GLU 407 372 ?   ?   ?   D . n 
D 1 408 VAL 408 373 ?   ?   ?   D . n 
D 1 409 LYS 409 374 ?   ?   ?   D . n 
D 1 410 PRO 410 375 ?   ?   ?   D . n 
D 1 411 GLU 411 376 ?   ?   ?   D . n 
D 1 412 THR 412 377 ?   ?   ?   D . n 
D 1 413 LYS 413 378 ?   ?   ?   D . n 
D 1 414 PRO 414 379 ?   ?   ?   D . n 
D 1 415 PRO 415 380 ?   ?   ?   D . n 
D 1 416 GLU 416 381 ?   ?   ?   D . n 
D 1 417 PRO 417 382 ?   ?   ?   D . n 
D 1 418 LYS 418 383 ?   ?   ?   D . n 
D 1 419 LYS 419 384 384 LYS LYS D . n 
D 1 420 THR 420 385 385 THR THR D . n 
D 1 421 PHE 421 386 386 PHE PHE D . n 
D 1 422 ASN 422 387 387 ASN ASN D . n 
D 1 423 SER 423 388 388 SER SER D . n 
D 1 424 VAL 424 389 389 VAL VAL D . n 
D 1 425 SER 425 390 390 SER SER D . n 
D 1 426 LYS 426 391 391 LYS LYS D . n 
D 1 427 ILE 427 392 392 ILE ILE D . n 
D 1 428 ASP 428 393 393 ASP ASP D . n 
D 1 429 ARG 429 394 394 ARG ARG D . n 
D 1 430 LEU 430 395 395 LEU LEU D . n 
D 1 431 SER 431 396 396 SER SER D . n 
D 1 432 ARG 432 397 397 ARG ARG D . n 
D 1 433 ILE 433 398 398 ILE ILE D . n 
D 1 434 ALA 434 399 399 ALA ALA D . n 
D 1 435 PHE 435 400 400 PHE PHE D . n 
D 1 436 PRO 436 401 401 PRO PRO D . n 
D 1 437 LEU 437 402 402 LEU LEU D . n 
D 1 438 LEU 438 403 403 LEU LEU D . n 
D 1 439 PHE 439 404 404 PHE PHE D . n 
D 1 440 GLY 440 405 405 GLY GLY D . n 
D 1 441 ILE 441 406 406 ILE ILE D . n 
D 1 442 PHE 442 407 407 PHE PHE D . n 
D 1 443 ASN 443 408 408 ASN ASN D . n 
D 1 444 LEU 444 409 409 LEU LEU D . n 
D 1 445 VAL 445 410 410 VAL VAL D . n 
D 1 446 TYR 446 411 411 TYR TYR D . n 
D 1 447 TRP 447 412 412 TRP TRP D . n 
D 1 448 ALA 448 413 413 ALA ALA D . n 
D 1 449 THR 449 414 414 THR THR D . n 
D 1 450 TYR 450 415 415 TYR TYR D . n 
D 1 451 LEU 451 416 416 LEU LEU D . n 
D 1 452 ASN 452 417 ?   ?   ?   D . n 
D 1 453 ARG 453 418 ?   ?   ?   D . n 
D 1 454 GLU 454 419 ?   ?   ?   D . n 
D 1 455 PRO 455 420 ?   ?   ?   D . n 
D 1 456 GLN 456 421 ?   ?   ?   D . n 
D 1 457 LEU 457 422 ?   ?   ?   D . n 
D 1 458 LYS 458 423 ?   ?   ?   D . n 
D 1 459 ALA 459 424 ?   ?   ?   D . n 
D 1 460 PRO 460 425 ?   ?   ?   D . n 
D 1 461 THR 461 426 ?   ?   ?   D . n 
D 1 462 PRO 462 427 ?   ?   ?   D . n 
D 1 463 HIS 463 428 ?   ?   ?   D . n 
D 1 464 GLN 464 429 ?   ?   ?   D . n 
E 2 1   MET 1   -24 ?   ?   ?   E . n 
E 2 2   CYS 2   -23 ?   ?   ?   E . n 
E 2 3   SER 3   -22 ?   ?   ?   E . n 
E 2 4   GLY 4   -21 ?   ?   ?   E . n 
E 2 5   LEU 5   -20 ?   ?   ?   E . n 
E 2 6   LEU 6   -19 ?   ?   ?   E . n 
E 2 7   GLU 7   -18 ?   ?   ?   E . n 
E 2 8   LEU 8   -17 ?   ?   ?   E . n 
E 2 9   LEU 9   -16 ?   ?   ?   E . n 
E 2 10  LEU 10  -15 ?   ?   ?   E . n 
E 2 11  PRO 11  -14 ?   ?   ?   E . n 
E 2 12  ILE 12  -13 ?   ?   ?   E . n 
E 2 13  TRP 13  -12 ?   ?   ?   E . n 
E 2 14  LEU 14  -11 ?   ?   ?   E . n 
E 2 15  SER 15  -10 ?   ?   ?   E . n 
E 2 16  TRP 16  -9  ?   ?   ?   E . n 
E 2 17  THR 17  -8  ?   ?   ?   E . n 
E 2 18  LEU 18  -7  ?   ?   ?   E . n 
E 2 19  GLY 19  -6  ?   ?   ?   E . n 
E 2 20  THR 20  -5  ?   ?   ?   E . n 
E 2 21  ARG 21  -4  ?   ?   ?   E . n 
E 2 22  GLY 22  -3  ?   ?   ?   E . n 
E 2 23  SER 23  -2  ?   ?   ?   E . n 
E 2 24  GLU 24  -1  ?   ?   ?   E . n 
E 2 25  PRO 25  0   ?   ?   ?   E . n 
E 2 26  ARG 26  1   ?   ?   ?   E . n 
E 2 27  SER 27  2   ?   ?   ?   E . n 
E 2 28  VAL 28  3   ?   ?   ?   E . n 
E 2 29  ASN 29  4   ?   ?   ?   E . n 
E 2 30  ASP 30  5   ?   ?   ?   E . n 
E 2 31  PRO 31  6   ?   ?   ?   E . n 
E 2 32  GLY 32  7   ?   ?   ?   E . n 
E 2 33  ASN 33  8   ?   ?   ?   E . n 
E 2 34  MET 34  9   9   MET MET E . n 
E 2 35  SER 35  10  10  SER SER E . n 
E 2 36  PHE 36  11  11  PHE PHE E . n 
E 2 37  VAL 37  12  12  VAL VAL E . n 
E 2 38  LYS 38  13  13  LYS LYS E . n 
E 2 39  GLU 39  14  14  GLU GLU E . n 
E 2 40  THR 40  15  15  THR THR E . n 
E 2 41  VAL 41  16  16  VAL VAL E . n 
E 2 42  ASP 42  17  17  ASP ASP E . n 
E 2 43  LYS 43  18  18  LYS LYS E . n 
E 2 44  LEU 44  19  19  LEU LEU E . n 
E 2 45  LEU 45  20  20  LEU LEU E . n 
E 2 46  LYS 46  21  21  LYS LYS E . n 
E 2 47  GLY 47  22  22  GLY GLY E . n 
E 2 48  TYR 48  23  23  TYR TYR E . n 
E 2 49  ASP 49  24  24  ASP ASP E . n 
E 2 50  ILE 50  25  25  ILE ILE E . n 
E 2 51  ARG 51  26  26  ARG ARG E . n 
E 2 52  LEU 52  27  27  LEU LEU E . n 
E 2 53  ARG 53  28  28  ARG ARG E . n 
E 2 54  PRO 54  29  29  PRO PRO E . n 
E 2 55  ASP 55  30  30  ASP ASP E . n 
E 2 56  PHE 56  31  31  PHE PHE E . n 
E 2 57  GLY 57  32  32  GLY GLY E . n 
E 2 58  GLY 58  33  33  GLY GLY E . n 
E 2 59  PRO 59  34  34  PRO PRO E . n 
E 2 60  PRO 60  35  35  PRO PRO E . n 
E 2 61  VAL 61  36  36  VAL VAL E . n 
E 2 62  CYS 62  37  37  CYS CYS E . n 
E 2 63  VAL 63  38  38  VAL VAL E . n 
E 2 64  GLY 64  39  39  GLY GLY E . n 
E 2 65  MET 65  40  40  MET MET E . n 
E 2 66  ASN 66  41  41  ASN ASN E . n 
E 2 67  ILE 67  42  42  ILE ILE E . n 
E 2 68  ASP 68  43  43  ASP ASP E . n 
E 2 69  ILE 69  44  44  ILE ILE E . n 
E 2 70  ALA 70  45  45  ALA ALA E . n 
E 2 71  SER 71  46  46  SER SER E . n 
E 2 72  ILE 72  47  47  ILE ILE E . n 
E 2 73  ASP 73  48  48  ASP ASP E . n 
E 2 74  MET 74  49  49  MET MET E . n 
E 2 75  VAL 75  50  50  VAL VAL E . n 
E 2 76  SER 76  51  51  SER SER E . n 
E 2 77  GLU 77  52  52  GLU GLU E . n 
E 2 78  VAL 78  53  53  VAL VAL E . n 
E 2 79  ASN 79  54  54  ASN ASN E . n 
E 2 80  MET 80  55  55  MET MET E . n 
E 2 81  ASP 81  56  56  ASP ASP E . n 
E 2 82  TYR 82  57  57  TYR TYR E . n 
E 2 83  THR 83  58  58  THR THR E . n 
E 2 84  LEU 84  59  59  LEU LEU E . n 
E 2 85  THR 85  60  60  THR THR E . n 
E 2 86  MET 86  61  61  MET MET E . n 
E 2 87  TYR 87  62  62  TYR TYR E . n 
E 2 88  PHE 88  63  63  PHE PHE E . n 
E 2 89  GLN 89  64  64  GLN GLN E . n 
E 2 90  GLN 90  65  65  GLN GLN E . n 
E 2 91  TYR 91  66  66  TYR TYR E . n 
E 2 92  TRP 92  67  67  TRP TRP E . n 
E 2 93  ARG 93  68  68  ARG ARG E . n 
E 2 94  ASP 94  69  69  ASP ASP E . n 
E 2 95  LYS 95  70  70  LYS LYS E . n 
E 2 96  ARG 96  71  71  ARG ARG E . n 
E 2 97  LEU 97  72  72  LEU LEU E . n 
E 2 98  ALA 98  73  73  ALA ALA E . n 
E 2 99  TYR 99  74  74  TYR TYR E . n 
E 2 100 SER 100 75  75  SER SER E . n 
E 2 101 GLY 101 76  76  GLY GLY E . n 
E 2 102 ILE 102 77  77  ILE ILE E . n 
E 2 103 PRO 103 78  78  PRO PRO E . n 
E 2 104 LEU 104 79  79  LEU LEU E . n 
E 2 105 ASN 105 80  80  ASN ASN E . n 
E 2 106 LEU 106 81  81  LEU LEU E . n 
E 2 107 THR 107 82  82  THR THR E . n 
E 2 108 LEU 108 83  83  LEU LEU E . n 
E 2 109 ASP 109 84  84  ASP ASP E . n 
E 2 110 ASN 110 85  85  ASN ASN E . n 
E 2 111 ARG 111 86  86  ARG ARG E . n 
E 2 112 VAL 112 87  87  VAL VAL E . n 
E 2 113 ALA 113 88  88  ALA ALA E . n 
E 2 114 ASP 114 89  89  ASP ASP E . n 
E 2 115 GLN 115 90  90  GLN GLN E . n 
E 2 116 LEU 116 91  91  LEU LEU E . n 
E 2 117 TRP 117 92  92  TRP TRP E . n 
E 2 118 VAL 118 93  93  VAL VAL E . n 
E 2 119 PRO 119 94  94  PRO PRO E . n 
E 2 120 ASP 120 95  95  ASP ASP E . n 
E 2 121 THR 121 96  96  THR THR E . n 
E 2 122 TYR 122 97  97  TYR TYR E . n 
E 2 123 PHE 123 98  98  PHE PHE E . n 
E 2 124 LEU 124 99  99  LEU LEU E . n 
E 2 125 ASN 125 100 100 ASN ASN E . n 
E 2 126 ASP 126 101 101 ASP ASP E . n 
E 2 127 LYS 127 102 102 LYS LYS E . n 
E 2 128 LYS 128 103 103 LYS LYS E . n 
E 2 129 SER 129 104 104 SER SER E . n 
E 2 130 PHE 130 105 105 PHE PHE E . n 
E 2 131 VAL 131 106 106 VAL VAL E . n 
E 2 132 HIS 132 107 107 HIS HIS E . n 
E 2 133 GLY 133 108 108 GLY GLY E . n 
E 2 134 VAL 134 109 109 VAL VAL E . n 
E 2 135 THR 135 110 110 THR THR E . n 
E 2 136 VAL 136 111 111 VAL VAL E . n 
E 2 137 LYS 137 112 112 LYS LYS E . n 
E 2 138 ASN 138 113 113 ASN ASN E . n 
E 2 139 ARG 139 114 114 ARG ARG E . n 
E 2 140 MET 140 115 115 MET MET E . n 
E 2 141 ILE 141 116 116 ILE ILE E . n 
E 2 142 ARG 142 117 117 ARG ARG E . n 
E 2 143 LEU 143 118 118 LEU LEU E . n 
E 2 144 HIS 144 119 119 HIS HIS E . n 
E 2 145 PRO 145 120 120 PRO PRO E . n 
E 2 146 ASP 146 121 121 ASP ASP E . n 
E 2 147 GLY 147 122 122 GLY GLY E . n 
E 2 148 THR 148 123 123 THR THR E . n 
E 2 149 VAL 149 124 124 VAL VAL E . n 
E 2 150 LEU 150 125 125 LEU LEU E . n 
E 2 151 TYR 151 126 126 TYR TYR E . n 
E 2 152 GLY 152 127 127 GLY GLY E . n 
E 2 153 LEU 153 128 128 LEU LEU E . n 
E 2 154 ARG 154 129 129 ARG ARG E . n 
E 2 155 ILE 155 130 130 ILE ILE E . n 
E 2 156 THR 156 131 131 THR THR E . n 
E 2 157 THR 157 132 132 THR THR E . n 
E 2 158 THR 158 133 133 THR THR E . n 
E 2 159 ALA 159 134 134 ALA ALA E . n 
E 2 160 ALA 160 135 135 ALA ALA E . n 
E 2 161 CYS 161 136 136 CYS CYS E . n 
E 2 162 MET 162 137 137 MET MET E . n 
E 2 163 MET 163 138 138 MET MET E . n 
E 2 164 ASP 164 139 139 ASP ASP E . n 
E 2 165 LEU 165 140 140 LEU LEU E . n 
E 2 166 ARG 166 141 141 ARG ARG E . n 
E 2 167 ARG 167 142 142 ARG ARG E . n 
E 2 168 TYR 168 143 143 TYR TYR E . n 
E 2 169 PRO 169 144 144 PRO PRO E . n 
E 2 170 LEU 170 145 145 LEU LEU E . n 
E 2 171 ASP 171 146 146 ASP ASP E . n 
E 2 172 GLU 172 147 147 GLU GLU E . n 
E 2 173 GLN 173 148 148 GLN GLN E . n 
E 2 174 ASN 174 149 149 ASN ASN E . n 
E 2 175 CYS 175 150 150 CYS CYS E . n 
E 2 176 THR 176 151 151 THR THR E . n 
E 2 177 LEU 177 152 152 LEU LEU E . n 
E 2 178 GLU 178 153 153 GLU GLU E . n 
E 2 179 ILE 179 154 154 ILE ILE E . n 
E 2 180 GLU 180 155 155 GLU GLU E . n 
E 2 181 SER 181 156 156 SER SER E . n 
E 2 182 TYR 182 157 157 TYR TYR E . n 
E 2 183 GLY 183 158 158 GLY GLY E . n 
E 2 184 TYR 184 159 159 TYR TYR E . n 
E 2 185 THR 185 160 160 THR THR E . n 
E 2 186 THR 186 161 161 THR THR E . n 
E 2 187 ASP 187 162 162 ASP ASP E . n 
E 2 188 ASP 188 163 163 ASP ASP E . n 
E 2 189 ILE 189 164 164 ILE ILE E . n 
E 2 190 GLU 190 165 165 GLU GLU E . n 
E 2 191 PHE 191 166 166 PHE PHE E . n 
E 2 192 TYR 192 167 167 TYR TYR E . n 
E 2 193 TRP 193 168 168 TRP TRP E . n 
E 2 194 ARG 194 169 169 ARG ARG E . n 
E 2 195 GLY 195 170 170 GLY GLY E . n 
E 2 196 GLY 196 171 171 GLY GLY E . n 
E 2 197 ASP 197 172 172 ASP ASP E . n 
E 2 198 LYS 198 173 173 LYS LYS E . n 
E 2 199 ALA 199 174 174 ALA ALA E . n 
E 2 200 VAL 200 175 175 VAL VAL E . n 
E 2 201 THR 201 176 176 THR THR E . n 
E 2 202 GLY 202 177 177 GLY GLY E . n 
E 2 203 VAL 203 178 178 VAL VAL E . n 
E 2 204 GLU 204 179 179 GLU GLU E . n 
E 2 205 ARG 205 180 180 ARG ARG E . n 
E 2 206 ILE 206 181 181 ILE ILE E . n 
E 2 207 GLU 207 182 182 GLU GLU E . n 
E 2 208 LEU 208 183 183 LEU LEU E . n 
E 2 209 PRO 209 184 184 PRO PRO E . n 
E 2 210 GLN 210 185 185 GLN GLN E . n 
E 2 211 PHE 211 186 186 PHE PHE E . n 
E 2 212 SER 212 187 187 SER SER E . n 
E 2 213 ILE 213 188 188 ILE ILE E . n 
E 2 214 VAL 214 189 189 VAL VAL E . n 
E 2 215 GLU 215 190 190 GLU GLU E . n 
E 2 216 HIS 216 191 191 HIS HIS E . n 
E 2 217 ARG 217 192 192 ARG ARG E . n 
E 2 218 LEU 218 193 193 LEU LEU E . n 
E 2 219 VAL 219 194 194 VAL VAL E . n 
E 2 220 SER 220 195 195 SER SER E . n 
E 2 221 ARG 221 196 196 ARG ARG E . n 
E 2 222 ASN 222 197 197 ASN ASN E . n 
E 2 223 VAL 223 198 198 VAL VAL E . n 
E 2 224 VAL 224 199 199 VAL VAL E . n 
E 2 225 PHE 225 200 200 PHE PHE E . n 
E 2 226 ALA 226 201 201 ALA ALA E . n 
E 2 227 THR 227 202 202 THR THR E . n 
E 2 228 GLY 228 203 203 GLY GLY E . n 
E 2 229 ALA 229 204 204 ALA ALA E . n 
E 2 230 TYR 230 205 205 TYR TYR E . n 
E 2 231 PRO 231 206 206 PRO PRO E . n 
E 2 232 ARG 232 207 207 ARG ARG E . n 
E 2 233 LEU 233 208 208 LEU LEU E . n 
E 2 234 SER 234 209 209 SER SER E . n 
E 2 235 LEU 235 210 210 LEU LEU E . n 
E 2 236 SER 236 211 211 SER SER E . n 
E 2 237 PHE 237 212 212 PHE PHE E . n 
E 2 238 ARG 238 213 213 ARG ARG E . n 
E 2 239 LEU 239 214 214 LEU LEU E . n 
E 2 240 LYS 240 215 215 LYS LYS E . n 
E 2 241 ARG 241 216 216 ARG ARG E . n 
E 2 242 ASN 242 217 217 ASN ASN E . n 
E 2 243 ILE 243 218 218 ILE ILE E . n 
E 2 244 GLY 244 219 219 GLY GLY E . n 
E 2 245 TYR 245 220 220 TYR TYR E . n 
E 2 246 PHE 246 221 221 PHE PHE E . n 
E 2 247 ILE 247 222 222 ILE ILE E . n 
E 2 248 LEU 248 223 223 LEU LEU E . n 
E 2 249 GLN 249 224 224 GLN GLN E . n 
E 2 250 THR 250 225 225 THR THR E . n 
E 2 251 TYR 251 226 226 TYR TYR E . n 
E 2 252 MET 252 227 227 MET MET E . n 
E 2 253 PRO 253 228 228 PRO PRO E . n 
E 2 254 SER 254 229 229 SER SER E . n 
E 2 255 ILE 255 230 230 ILE ILE E . n 
E 2 256 LEU 256 231 231 LEU LEU E . n 
E 2 257 ILE 257 232 232 ILE ILE E . n 
E 2 258 THR 258 233 233 THR THR E . n 
E 2 259 ILE 259 234 234 ILE ILE E . n 
E 2 260 LEU 260 235 235 LEU LEU E . n 
E 2 261 SER 261 236 236 SER SER E . n 
E 2 262 TRP 262 237 237 TRP TRP E . n 
E 2 263 VAL 263 238 238 VAL VAL E . n 
E 2 264 SER 264 239 239 SER SER E . n 
E 2 265 PHE 265 240 240 PHE PHE E . n 
E 2 266 TRP 266 241 241 TRP TRP E . n 
E 2 267 ILE 267 242 242 ILE ILE E . n 
E 2 268 ASN 268 243 243 ASN ASN E . n 
E 2 269 TYR 269 244 244 TYR TYR E . n 
E 2 270 ASP 270 245 245 ASP ASP E . n 
E 2 271 ALA 271 246 246 ALA ALA E . n 
E 2 272 SER 272 247 247 SER SER E . n 
E 2 273 ALA 273 248 248 ALA ALA E . n 
E 2 274 ALA 274 249 249 ALA ALA E . n 
E 2 275 ARG 275 250 250 ARG ARG E . n 
E 2 276 VAL 276 251 251 VAL VAL E . n 
E 2 277 ALA 277 252 252 ALA ALA E . n 
E 2 278 LEU 278 253 253 LEU LEU E . n 
E 2 279 GLY 279 254 254 GLY GLY E . n 
E 2 280 ILE 280 255 255 ILE ILE E . n 
E 2 281 THR 281 256 256 THR THR E . n 
E 2 282 THR 282 257 257 THR THR E . n 
E 2 283 VAL 283 258 258 VAL VAL E . n 
E 2 284 LEU 284 259 259 LEU LEU E . n 
E 2 285 THR 285 260 260 THR THR E . n 
E 2 286 MET 286 261 261 MET MET E . n 
E 2 287 THR 287 262 262 THR THR E . n 
E 2 288 THR 288 263 263 THR THR E . n 
E 2 289 ILE 289 264 264 ILE ILE E . n 
E 2 290 ASN 290 265 265 ASN ASN E . n 
E 2 291 THR 291 266 266 THR THR E . n 
E 2 292 HIS 292 267 267 HIS HIS E . n 
E 2 293 LEU 293 268 268 LEU LEU E . n 
E 2 294 ARG 294 269 269 ARG ARG E . n 
E 2 295 GLU 295 270 270 GLU GLU E . n 
E 2 296 THR 296 271 271 THR THR E . n 
E 2 297 LEU 297 272 272 LEU LEU E . n 
E 2 298 PRO 298 273 273 PRO PRO E . n 
E 2 299 LYS 299 274 274 LYS LYS E . n 
E 2 300 ILE 300 275 275 ILE ILE E . n 
E 2 301 PRO 301 276 276 PRO PRO E . n 
E 2 302 TYR 302 277 277 TYR TYR E . n 
E 2 303 VAL 303 278 278 VAL VAL E . n 
E 2 304 LYS 304 279 279 LYS LYS E . n 
E 2 305 ALA 305 280 280 ALA ALA E . n 
E 2 306 ILE 306 281 281 ILE ILE E . n 
E 2 307 ASP 307 282 282 ASP ASP E . n 
E 2 308 MET 308 283 283 MET MET E . n 
E 2 309 TYR 309 284 284 TYR TYR E . n 
E 2 310 LEU 310 285 285 LEU LEU E . n 
E 2 311 MET 311 286 286 MET MET E . n 
E 2 312 GLY 312 287 287 GLY GLY E . n 
E 2 313 CYS 313 288 288 CYS CYS E . n 
E 2 314 PHE 314 289 289 PHE PHE E . n 
E 2 315 VAL 315 290 290 VAL VAL E . n 
E 2 316 PHE 316 291 291 PHE PHE E . n 
E 2 317 VAL 317 292 292 VAL VAL E . n 
E 2 318 PHE 318 293 293 PHE PHE E . n 
E 2 319 LEU 319 294 294 LEU LEU E . n 
E 2 320 ALA 320 295 295 ALA ALA E . n 
E 2 321 LEU 321 296 296 LEU LEU E . n 
E 2 322 LEU 322 297 297 LEU LEU E . n 
E 2 323 GLU 323 298 298 GLU GLU E . n 
E 2 324 TYR 324 299 299 TYR TYR E . n 
E 2 325 ALA 325 300 300 ALA ALA E . n 
E 2 326 PHE 326 301 301 PHE PHE E . n 
E 2 327 VAL 327 302 302 VAL VAL E . n 
E 2 328 ASN 328 303 303 ASN ASN E . n 
E 2 329 TYR 329 304 304 TYR TYR E . n 
E 2 330 ILE 330 305 305 ILE ILE E . n 
E 2 331 PHE 331 306 306 PHE PHE E . n 
E 2 332 PHE 332 307 307 PHE PHE E . n 
E 2 333 GLY 333 308 308 GLY GLY E . n 
E 2 334 ARG 334 309 309 ARG ARG E . n 
E 2 335 GLY 335 335 ?   ?   ?   E . n 
E 2 336 PRO 336 336 ?   ?   ?   E . n 
E 2 337 GLN 337 337 ?   ?   ?   E . n 
E 2 338 ARG 338 338 ?   ?   ?   E . n 
E 2 339 GLN 339 339 ?   ?   ?   E . n 
E 2 340 LYS 340 340 ?   ?   ?   E . n 
E 2 341 LYS 341 341 ?   ?   ?   E . n 
E 2 342 LEU 342 342 ?   ?   ?   E . n 
E 2 343 ALA 343 343 ?   ?   ?   E . n 
E 2 344 GLU 344 344 ?   ?   ?   E . n 
E 2 345 LYS 345 345 ?   ?   ?   E . n 
E 2 346 THR 346 346 ?   ?   ?   E . n 
E 2 347 ALA 347 347 ?   ?   ?   E . n 
E 2 348 LYS 348 348 ?   ?   ?   E . n 
E 2 349 ALA 349 349 ?   ?   ?   E . n 
E 2 350 LYS 350 350 ?   ?   ?   E . n 
E 2 351 ASN 351 351 ?   ?   ?   E . n 
E 2 352 ASP 352 352 ?   ?   ?   E . n 
E 2 353 ARG 353 353 ?   ?   ?   E . n 
E 2 354 SER 354 354 ?   ?   ?   E . n 
E 2 355 LYS 355 355 ?   ?   ?   E . n 
E 2 356 SER 356 356 ?   ?   ?   E . n 
E 2 357 GLU 357 357 ?   ?   ?   E . n 
E 2 358 SER 358 358 ?   ?   ?   E . n 
E 2 359 ASN 359 359 ?   ?   ?   E . n 
E 2 360 ARG 360 360 ?   ?   ?   E . n 
E 2 361 VAL 361 361 ?   ?   ?   E . n 
E 2 362 ASP 362 362 ?   ?   ?   E . n 
E 2 363 ALA 363 363 ?   ?   ?   E . n 
E 2 364 HIS 364 364 ?   ?   ?   E . n 
E 2 365 GLY 365 365 ?   ?   ?   E . n 
E 2 366 ASN 366 366 ?   ?   ?   E . n 
E 2 367 ILE 367 367 ?   ?   ?   E . n 
E 2 368 LEU 368 368 ?   ?   ?   E . n 
E 2 369 LEU 369 369 ?   ?   ?   E . n 
E 2 370 THR 370 370 ?   ?   ?   E . n 
E 2 371 SER 371 371 ?   ?   ?   E . n 
E 2 372 LEU 372 372 ?   ?   ?   E . n 
E 2 373 GLU 373 373 ?   ?   ?   E . n 
E 2 374 VAL 374 374 ?   ?   ?   E . n 
E 2 375 HIS 375 375 ?   ?   ?   E . n 
E 2 376 ASN 376 376 ?   ?   ?   E . n 
E 2 377 GLU 377 377 ?   ?   ?   E . n 
E 2 378 MET 378 378 ?   ?   ?   E . n 
E 2 379 ASN 379 379 ?   ?   ?   E . n 
E 2 380 GLU 380 380 ?   ?   ?   E . n 
E 2 381 VAL 381 381 ?   ?   ?   E . n 
E 2 382 SER 382 382 ?   ?   ?   E . n 
E 2 383 GLY 383 383 ?   ?   ?   E . n 
E 2 384 GLY 384 384 ?   ?   ?   E . n 
E 2 385 ILE 385 385 ?   ?   ?   E . n 
E 2 386 GLY 386 386 ?   ?   ?   E . n 
E 2 387 ASP 387 387 ?   ?   ?   E . n 
E 2 388 THR 388 388 ?   ?   ?   E . n 
E 2 389 ARG 389 389 ?   ?   ?   E . n 
E 2 390 ASN 390 390 ?   ?   ?   E . n 
E 2 391 SER 391 391 ?   ?   ?   E . n 
E 2 392 ALA 392 392 ?   ?   ?   E . n 
E 2 393 ILE 393 393 ?   ?   ?   E . n 
E 2 394 SER 394 394 ?   ?   ?   E . n 
E 2 395 PHE 395 395 ?   ?   ?   E . n 
E 2 396 ASP 396 396 ?   ?   ?   E . n 
E 2 397 ASN 397 397 ?   ?   ?   E . n 
E 2 398 SER 398 398 ?   ?   ?   E . n 
E 2 399 GLY 399 399 ?   ?   ?   E . n 
E 2 400 ILE 400 400 ?   ?   ?   E . n 
E 2 401 GLN 401 401 ?   ?   ?   E . n 
E 2 402 TYR 402 402 ?   ?   ?   E . n 
E 2 403 ARG 403 403 ?   ?   ?   E . n 
E 2 404 LYS 404 404 ?   ?   ?   E . n 
E 2 405 GLN 405 405 ?   ?   ?   E . n 
E 2 406 SER 406 406 ?   ?   ?   E . n 
E 2 407 MET 407 407 ?   ?   ?   E . n 
E 2 408 PRO 408 408 ?   ?   ?   E . n 
E 2 409 ARG 409 409 ?   ?   ?   E . n 
E 2 410 GLU 410 410 ?   ?   ?   E . n 
E 2 411 GLY 411 411 ?   ?   ?   E . n 
E 2 412 HIS 412 412 ?   ?   ?   E . n 
E 2 413 GLY 413 413 ?   ?   ?   E . n 
E 2 414 ARG 414 414 ?   ?   ?   E . n 
E 2 415 PHE 415 415 ?   ?   ?   E . n 
E 2 416 LEU 416 416 ?   ?   ?   E . n 
E 2 417 GLY 417 417 ?   ?   ?   E . n 
E 2 418 ASP 418 418 ?   ?   ?   E . n 
E 2 419 ARG 419 419 ?   ?   ?   E . n 
E 2 420 SER 420 420 ?   ?   ?   E . n 
E 2 421 LEU 421 421 ?   ?   ?   E . n 
E 2 422 PRO 422 422 ?   ?   ?   E . n 
E 2 423 HIS 423 423 ?   ?   ?   E . n 
E 2 424 LYS 424 424 ?   ?   ?   E . n 
E 2 425 LYS 425 425 ?   ?   ?   E . n 
E 2 426 THR 426 426 ?   ?   ?   E . n 
E 2 427 HIS 427 427 ?   ?   ?   E . n 
E 2 428 LEU 428 428 ?   ?   ?   E . n 
E 2 429 ARG 429 429 ?   ?   ?   E . n 
E 2 430 ARG 430 430 ?   ?   ?   E . n 
E 2 431 ARG 431 431 ?   ?   ?   E . n 
E 2 432 SER 432 432 ?   ?   ?   E . n 
E 2 433 SER 433 433 ?   ?   ?   E . n 
E 2 434 GLN 434 434 ?   ?   ?   E . n 
E 2 435 LEU 435 435 ?   ?   ?   E . n 
E 2 436 LYS 436 436 ?   ?   ?   E . n 
E 2 437 ILE 437 437 ?   ?   ?   E . n 
E 2 438 LYS 438 438 ?   ?   ?   E . n 
E 2 439 ILE 439 439 ?   ?   ?   E . n 
E 2 440 PRO 440 440 ?   ?   ?   E . n 
E 2 441 ASP 441 441 ?   ?   ?   E . n 
E 2 442 LEU 442 442 ?   ?   ?   E . n 
E 2 443 THR 443 443 ?   ?   ?   E . n 
E 2 444 ASP 444 444 444 ASP ASP E . n 
E 2 445 VAL 445 445 445 VAL VAL E . n 
E 2 446 ASN 446 446 446 ASN ASN E . n 
E 2 447 ALA 447 447 447 ALA ALA E . n 
E 2 448 ILE 448 448 448 ILE ILE E . n 
E 2 449 ASP 449 449 449 ASP ASP E . n 
E 2 450 ARG 450 450 450 ARG ARG E . n 
E 2 451 TRP 451 451 451 TRP TRP E . n 
E 2 452 SER 452 452 452 SER SER E . n 
E 2 453 ARG 453 453 453 ARG ARG E . n 
E 2 454 ILE 454 454 454 ILE ILE E . n 
E 2 455 VAL 455 455 455 VAL VAL E . n 
E 2 456 PHE 456 456 456 PHE PHE E . n 
E 2 457 PRO 457 457 457 PRO PRO E . n 
E 2 458 PHE 458 458 458 PHE PHE E . n 
E 2 459 THR 459 459 459 THR THR E . n 
E 2 460 PHE 460 460 460 PHE PHE E . n 
E 2 461 SER 461 461 461 SER SER E . n 
E 2 462 LEU 462 462 462 LEU LEU E . n 
E 2 463 PHE 463 463 463 PHE PHE E . n 
E 2 464 ASN 464 464 464 ASN ASN E . n 
E 2 465 LEU 465 465 465 LEU LEU E . n 
E 2 466 VAL 466 466 466 VAL VAL E . n 
E 2 467 TYR 467 467 467 TYR TYR E . n 
E 2 468 TRP 468 468 468 TRP TRP E . n 
E 2 469 LEU 469 469 469 LEU LEU E . n 
E 2 470 TYR 470 470 470 TYR TYR E . n 
E 2 471 TYR 471 471 471 TYR TYR E . n 
E 2 472 VAL 472 472 472 VAL VAL E . n 
E 2 473 ASN 473 473 ?   ?   ?   E . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
F 3 NAG 1 a NAG 1 a NAG 1 n 
F 3 NAG 2 a NAG 2 a NAG 2 n 
F 3 BMA 3 a BMA 3 a BMA 3 n 
F 3 MAN 4 a MAN 4 a MAN 5 n 
F 3 MAN 5 a MAN 5 a MAN 4 n 
G 3 NAG 1 b NAG 1 b NAG 1 n 
G 3 NAG 2 b NAG 2 b NAG 2 n 
G 3 BMA 3 b BMA 3 b BMA 3 n 
G 3 MAN 4 b MAN 4 b MAN 4 n 
G 3 MAN 5 b MAN 5 b MAN 5 n 
H 4 NAG 1 F NAG 1 b NAG 6 n 
H 4 NAG 2 F NAG 2 b NAG 7 n 
I 3 NAG 1 c NAG 1 c NAG 1 n 
I 3 NAG 2 c NAG 2 c NAG 2 n 
I 3 BMA 3 c BMA 3 c BMA 3 n 
I 3 MAN 4 c MAN 4 c MAN 4 n 
I 3 MAN 5 c MAN 5 c MAN 5 n 
J 4 NAG 1 G NAG 1 c NAG 6 n 
J 4 NAG 2 G NAG 2 c NAG 7 n 
K 3 NAG 1 d NAG 1 d NAG 1 n 
K 3 NAG 2 d NAG 2 d NAG 2 n 
K 3 BMA 3 d BMA 3 d BMA 3 n 
K 3 MAN 4 d MAN 4 d MAN 5 n 
K 3 MAN 5 d MAN 5 d MAN 4 n 
L 3 NAG 1 e NAG 1 e NAG 1 n 
L 3 NAG 2 e NAG 2 e NAG 2 n 
L 3 BMA 3 e BMA 3 e BMA 3 n 
L 3 MAN 4 e MAN 4 e MAN 4 n 
L 3 MAN 5 e MAN 5 e MAN 5 n 
M 4 NAG 1 H NAG 1 e NAG 6 n 
M 4 NAG 2 H NAG 2 e NAG 7 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
N 5 PIO 1 501 2 PIO PIO A . 
O 5 PIO 1 501 1 PIO PIO D . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FG4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FG4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FG4 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9FG4 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 14525 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.519 ? 19748 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 9.989 ? 5351  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.042 ? 2325  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 2405  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9FG4 
_struct.title                        
'Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in the long-lived symmetric resting state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FG4 
_struct_keywords.text            'GABA, neurotransmission, gating cycle, time-resolved cryo-EM, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 3 ? 
H N N 4 ? 
I N N 3 ? 
J N N 4 ? 
K N N 3 ? 
L N N 3 ? 
M N N 4 ? 
N N N 5 ? 
O N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GBRA1_HUMAN P14867 ?        1 
;QPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGP
MTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSY
AYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVIL
SQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGK
SVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAF
PLLFGIFNLVYWATYLNREPQLKAPTPHQ
;
28 
2 UNP GBRB3_HUMAN P28472 P28472-2 2 
;MCSGLLELLLPIWLSWTLGTRGSEPRSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNM
DYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA
CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLA
LLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGI
QYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
;
1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9FG4 A 36 ? 464 ? P14867 28 ? 456 ? 1   429 
2 2 9FG4 B 1  ? 473 ? P28472 1  ? 473 ? -24 473 
3 2 9FG4 C 1  ? 473 ? P28472 1  ? 473 ? -24 473 
4 1 9FG4 D 36 ? 464 ? P14867 28 ? 456 ? 1   429 
5 2 9FG4 E 1  ? 473 ? P28472 1  ? 473 ? -24 473 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9FG4 MET A 1  ? UNP P14867 ? ? 'initiating methionine' -34 1  
1 9FG4 LYS A 2  ? UNP P14867 ? ? 'expression tag'        -33 2  
1 9FG4 LYS A 3  ? UNP P14867 ? ? 'expression tag'        -32 3  
1 9FG4 SER A 4  ? UNP P14867 ? ? 'expression tag'        -31 4  
1 9FG4 PRO A 5  ? UNP P14867 ? ? 'expression tag'        -30 5  
1 9FG4 GLY A 6  ? UNP P14867 ? ? 'expression tag'        -29 6  
1 9FG4 LEU A 7  ? UNP P14867 ? ? 'expression tag'        -28 7  
1 9FG4 SER A 8  ? UNP P14867 ? ? 'expression tag'        -27 8  
1 9FG4 ASP A 9  ? UNP P14867 ? ? 'expression tag'        -26 9  
1 9FG4 TYR A 10 ? UNP P14867 ? ? 'expression tag'        -25 10 
1 9FG4 LEU A 11 ? UNP P14867 ? ? 'expression tag'        -24 11 
1 9FG4 TRP A 12 ? UNP P14867 ? ? 'expression tag'        -23 12 
1 9FG4 ALA A 13 ? UNP P14867 ? ? 'expression tag'        -22 13 
1 9FG4 TRP A 14 ? UNP P14867 ? ? 'expression tag'        -21 14 
1 9FG4 THR A 15 ? UNP P14867 ? ? 'expression tag'        -20 15 
1 9FG4 LEU A 16 ? UNP P14867 ? ? 'expression tag'        -19 16 
1 9FG4 PHE A 17 ? UNP P14867 ? ? 'expression tag'        -18 17 
1 9FG4 LEU A 18 ? UNP P14867 ? ? 'expression tag'        -17 18 
1 9FG4 SER A 19 ? UNP P14867 ? ? 'expression tag'        -16 19 
1 9FG4 THR A 20 ? UNP P14867 ? ? 'expression tag'        -15 20 
1 9FG4 LEU A 21 ? UNP P14867 ? ? 'expression tag'        -14 21 
1 9FG4 THR A 22 ? UNP P14867 ? ? 'expression tag'        -13 22 
1 9FG4 GLY A 23 ? UNP P14867 ? ? 'expression tag'        -12 23 
1 9FG4 ARG A 24 ? UNP P14867 ? ? 'expression tag'        -11 24 
1 9FG4 SER A 25 ? UNP P14867 ? ? 'expression tag'        -10 25 
1 9FG4 TYR A 26 ? UNP P14867 ? ? 'expression tag'        -9  26 
1 9FG4 GLY A 27 ? UNP P14867 ? ? 'expression tag'        -8  27 
1 9FG4 ASP A 28 ? UNP P14867 ? ? 'expression tag'        -7  28 
1 9FG4 TYR A 29 ? UNP P14867 ? ? 'expression tag'        -6  29 
1 9FG4 LYS A 30 ? UNP P14867 ? ? 'expression tag'        -5  30 
1 9FG4 ASP A 31 ? UNP P14867 ? ? 'expression tag'        -4  31 
1 9FG4 ASP A 32 ? UNP P14867 ? ? 'expression tag'        -3  32 
1 9FG4 ASP A 33 ? UNP P14867 ? ? 'expression tag'        -2  33 
1 9FG4 ASP A 34 ? UNP P14867 ? ? 'expression tag'        -1  34 
1 9FG4 LYS A 35 ? UNP P14867 ? ? 'expression tag'        0   35 
4 9FG4 MET D 1  ? UNP P14867 ? ? 'initiating methionine' -34 36 
4 9FG4 LYS D 2  ? UNP P14867 ? ? 'expression tag'        -33 37 
4 9FG4 LYS D 3  ? UNP P14867 ? ? 'expression tag'        -32 38 
4 9FG4 SER D 4  ? UNP P14867 ? ? 'expression tag'        -31 39 
4 9FG4 PRO D 5  ? UNP P14867 ? ? 'expression tag'        -30 40 
4 9FG4 GLY D 6  ? UNP P14867 ? ? 'expression tag'        -29 41 
4 9FG4 LEU D 7  ? UNP P14867 ? ? 'expression tag'        -28 42 
4 9FG4 SER D 8  ? UNP P14867 ? ? 'expression tag'        -27 43 
4 9FG4 ASP D 9  ? UNP P14867 ? ? 'expression tag'        -26 44 
4 9FG4 TYR D 10 ? UNP P14867 ? ? 'expression tag'        -25 45 
4 9FG4 LEU D 11 ? UNP P14867 ? ? 'expression tag'        -24 46 
4 9FG4 TRP D 12 ? UNP P14867 ? ? 'expression tag'        -23 47 
4 9FG4 ALA D 13 ? UNP P14867 ? ? 'expression tag'        -22 48 
4 9FG4 TRP D 14 ? UNP P14867 ? ? 'expression tag'        -21 49 
4 9FG4 THR D 15 ? UNP P14867 ? ? 'expression tag'        -20 50 
4 9FG4 LEU D 16 ? UNP P14867 ? ? 'expression tag'        -19 51 
4 9FG4 PHE D 17 ? UNP P14867 ? ? 'expression tag'        -18 52 
4 9FG4 LEU D 18 ? UNP P14867 ? ? 'expression tag'        -17 53 
4 9FG4 SER D 19 ? UNP P14867 ? ? 'expression tag'        -16 54 
4 9FG4 THR D 20 ? UNP P14867 ? ? 'expression tag'        -15 55 
4 9FG4 LEU D 21 ? UNP P14867 ? ? 'expression tag'        -14 56 
4 9FG4 THR D 22 ? UNP P14867 ? ? 'expression tag'        -13 57 
4 9FG4 GLY D 23 ? UNP P14867 ? ? 'expression tag'        -12 58 
4 9FG4 ARG D 24 ? UNP P14867 ? ? 'expression tag'        -11 59 
4 9FG4 SER D 25 ? UNP P14867 ? ? 'expression tag'        -10 60 
4 9FG4 TYR D 26 ? UNP P14867 ? ? 'expression tag'        -9  61 
4 9FG4 GLY D 27 ? UNP P14867 ? ? 'expression tag'        -8  62 
4 9FG4 ASP D 28 ? UNP P14867 ? ? 'expression tag'        -7  63 
4 9FG4 TYR D 29 ? UNP P14867 ? ? 'expression tag'        -6  64 
4 9FG4 LYS D 30 ? UNP P14867 ? ? 'expression tag'        -5  65 
4 9FG4 ASP D 31 ? UNP P14867 ? ? 'expression tag'        -4  66 
4 9FG4 ASP D 32 ? UNP P14867 ? ? 'expression tag'        -3  67 
4 9FG4 ASP D 33 ? UNP P14867 ? ? 'expression tag'        -2  68 
4 9FG4 ASP D 34 ? UNP P14867 ? ? 'expression tag'        -1  69 
4 9FG4 LYS D 35 ? UNP P14867 ? ? 'expression tag'        0   70 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 47  ? LEU A 58  ? THR A 12  LEU A 23  1 ? 12 
HELX_P HELX_P2  AA2 GLU A 108 ? LYS A 111 ? GLU A 73  LYS A 76  5 ? 4  
HELX_P HELX_P3  AA3 ASN A 122 ? SER A 127 ? ASN A 87  SER A 92  1 ? 6  
HELX_P HELX_P4  AA4 GLU A 209 ? ARG A 212 ? GLU A 174 ARG A 177 5 ? 4  
HELX_P HELX_P5  AA5 ILE A 258 ? THR A 265 ? ILE A 223 THR A 230 1 ? 8  
HELX_P HELX_P6  AA6 THR A 265 ? VAL A 278 ? THR A 230 VAL A 243 1 ? 14 
HELX_P HELX_P7  AA7 SER A 279 ? LEU A 282 ? SER A 244 LEU A 247 5 ? 4  
HELX_P HELX_P8  AA8 SER A 286 ? LEU A 312 ? SER A 251 LEU A 277 1 ? 27 
HELX_P HELX_P9  AA9 THR A 319 ? TYR A 344 ? THR A 284 TYR A 309 1 ? 26 
HELX_P HELX_P10 AB1 SER A 425 ? LEU A 451 ? SER A 390 LEU A 416 1 ? 27 
HELX_P HELX_P11 AB2 SER B 35  ? LYS B 46  ? SER B 10  LYS B 21  1 ? 12 
HELX_P HELX_P12 AB3 LYS B 95  ? ALA B 98  ? LYS B 70  ALA B 73  5 ? 4  
HELX_P HELX_P13 AB4 ASP B 109 ? LEU B 116 ? ASP B 84  LEU B 91  5 ? 8  
HELX_P HELX_P14 AB5 GLY B 195 ? LYS B 198 ? GLY B 170 LYS B 173 5 ? 4  
HELX_P HELX_P15 AB6 ILE B 243 ? THR B 250 ? ILE B 218 THR B 225 1 ? 8  
HELX_P HELX_P16 AB7 THR B 250 ? TRP B 262 ? THR B 225 TRP B 237 1 ? 13 
HELX_P HELX_P17 AB8 VAL B 263 ? ILE B 267 ? VAL B 238 ILE B 242 5 ? 5  
HELX_P HELX_P18 AB9 ALA B 271 ? LEU B 297 ? ALA B 246 LEU B 272 1 ? 27 
HELX_P HELX_P19 AC1 LYS B 304 ? GLY B 333 ? LYS B 279 GLY B 308 1 ? 30 
HELX_P HELX_P20 AC2 VAL B 445 ? VAL B 472 ? VAL B 445 VAL B 472 1 ? 28 
HELX_P HELX_P21 AC3 SER C 35  ? LYS C 46  ? SER C 10  LYS C 21  1 ? 12 
HELX_P HELX_P22 AC4 LYS C 95  ? ALA C 98  ? LYS C 70  ALA C 73  5 ? 4  
HELX_P HELX_P23 AC5 ASP C 109 ? LEU C 116 ? ASP C 84  LEU C 91  5 ? 8  
HELX_P HELX_P24 AC6 GLY C 195 ? LYS C 198 ? GLY C 170 LYS C 173 5 ? 4  
HELX_P HELX_P25 AC7 GLY C 202 ? ILE C 206 ? GLY C 177 ILE C 181 5 ? 5  
HELX_P HELX_P26 AC8 ILE C 243 ? THR C 250 ? ILE C 218 THR C 225 1 ? 8  
HELX_P HELX_P27 AC9 THR C 250 ? TRP C 262 ? THR C 225 TRP C 237 1 ? 13 
HELX_P HELX_P28 AD1 VAL C 263 ? ILE C 267 ? VAL C 238 ILE C 242 5 ? 5  
HELX_P HELX_P29 AD2 ALA C 271 ? LEU C 297 ? ALA C 246 LEU C 272 1 ? 27 
HELX_P HELX_P30 AD3 LYS C 304 ? GLY C 333 ? LYS C 279 GLY C 308 1 ? 30 
HELX_P HELX_P31 AD4 VAL C 445 ? VAL C 472 ? VAL C 445 VAL C 472 1 ? 28 
HELX_P HELX_P32 AD5 THR D 48  ? LEU D 58  ? THR D 13  LEU D 23  1 ? 11 
HELX_P HELX_P33 AD6 GLU D 108 ? LYS D 111 ? GLU D 73  LYS D 76  5 ? 4  
HELX_P HELX_P34 AD7 ASN D 122 ? SER D 127 ? ASN D 87  SER D 92  1 ? 6  
HELX_P HELX_P35 AD8 HIS D 177 ? PHE D 181 ? HIS D 142 PHE D 146 5 ? 5  
HELX_P HELX_P36 AD9 GLU D 209 ? SER D 213 ? GLU D 174 SER D 178 1 ? 5  
HELX_P HELX_P37 AE1 ILE D 258 ? THR D 265 ? ILE D 223 THR D 230 1 ? 8  
HELX_P HELX_P38 AE2 THR D 265 ? SER D 279 ? THR D 230 SER D 244 1 ? 15 
HELX_P HELX_P39 AE3 PHE D 280 ? LEU D 282 ? PHE D 245 LEU D 247 5 ? 3  
HELX_P HELX_P40 AE4 SER D 286 ? LEU D 312 ? SER D 251 LEU D 277 1 ? 27 
HELX_P HELX_P41 AE5 THR D 319 ? PHE D 345 ? THR D 284 PHE D 310 1 ? 27 
HELX_P HELX_P42 AE6 SER D 425 ? LEU D 451 ? SER D 390 LEU D 416 1 ? 27 
HELX_P HELX_P43 AE7 SER E 35  ? LYS E 46  ? SER E 10  LYS E 21  1 ? 12 
HELX_P HELX_P44 AE8 LYS E 95  ? ALA E 98  ? LYS E 70  ALA E 73  5 ? 4  
HELX_P HELX_P45 AE9 ASP E 109 ? LEU E 116 ? ASP E 84  LEU E 91  5 ? 8  
HELX_P HELX_P46 AF1 GLY E 195 ? LYS E 198 ? GLY E 170 LYS E 173 5 ? 4  
HELX_P HELX_P47 AF2 ILE E 243 ? THR E 250 ? ILE E 218 THR E 225 1 ? 8  
HELX_P HELX_P48 AF3 THR E 250 ? TRP E 262 ? THR E 225 TRP E 237 1 ? 13 
HELX_P HELX_P49 AF4 VAL E 263 ? ILE E 267 ? VAL E 238 ILE E 242 5 ? 5  
HELX_P HELX_P50 AF5 ALA E 271 ? HIS E 292 ? ALA E 246 HIS E 267 1 ? 22 
HELX_P HELX_P51 AF6 LEU E 293 ? LEU E 297 ? LEU E 268 LEU E 272 5 ? 5  
HELX_P HELX_P52 AF7 LYS E 304 ? GLY E 333 ? LYS E 279 GLY E 308 1 ? 30 
HELX_P HELX_P53 AF8 VAL E 445 ? VAL E 472 ? VAL E 445 VAL E 472 1 ? 28 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 174 SG  ? ? ? 1_555 A CYS 188 SG ? ? A CYS 139 A CYS 153 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf2  disulf ?    ? B CYS 161 SG  ? ? ? 1_555 B CYS 175 SG ? ? B CYS 136 B CYS 150 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf3  disulf ?    ? C CYS 161 SG  ? ? ? 1_555 C CYS 175 SG ? ? C CYS 136 C CYS 150 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf4  disulf ?    ? D CYS 174 SG  ? ? ? 1_555 D CYS 188 SG ? ? D CYS 139 D CYS 153 1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf5  disulf ?    ? E CYS 161 SG  ? ? ? 1_555 E CYS 175 SG ? ? E CYS 136 E CYS 150 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
covale1  covale one  ? A ASN 146 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 111 a NAG 1   1_555 ? ? ? ? ? ? ? 1.437 ? N-Glycosylation 
covale2  covale one  ? B ASN 105 ND2 ? ? ? 1_555 H NAG .   C1 ? ? B ASN 80  F NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale3  covale one  ? B ASN 174 ND2 ? ? ? 1_555 G NAG .   C1 ? ? B ASN 149 b NAG 1   1_555 ? ? ? ? ? ? ? 1.435 ? N-Glycosylation 
covale4  covale one  ? C ASN 105 ND2 ? ? ? 1_555 J NAG .   C1 ? ? C ASN 80  G NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale5  covale one  ? C ASN 174 ND2 ? ? ? 1_555 I NAG .   C1 ? ? C ASN 149 c NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale6  covale one  ? D ASN 146 ND2 ? ? ? 1_555 K NAG .   C1 ? ? D ASN 111 d NAG 1   1_555 ? ? ? ? ? ? ? 1.429 ? N-Glycosylation 
covale7  covale one  ? E ASN 105 ND2 ? ? ? 1_555 M NAG .   C1 ? ? E ASN 80  H NAG 1   1_555 ? ? ? ? ? ? ? 1.438 ? N-Glycosylation 
covale8  covale one  ? E ASN 174 ND2 ? ? ? 1_555 L NAG .   C1 ? ? E ASN 149 e NAG 1   1_555 ? ? ? ? ? ? ? 1.438 ? N-Glycosylation 
covale9  covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? a NAG 1   a NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale10 covale both ? F NAG .   O4  ? ? ? 1_555 F BMA .   C1 ? ? a NAG 2   a BMA 3   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale11 covale both ? F BMA .   O3  ? ? ? 1_555 F MAN .   C1 ? ? a BMA 3   a MAN 4   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale12 covale both ? F BMA .   O6  ? ? ? 1_555 F MAN .   C1 ? ? a BMA 3   a MAN 5   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale13 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? b NAG 1   b NAG 2   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale14 covale both ? G NAG .   O4  ? ? ? 1_555 G BMA .   C1 ? ? b NAG 2   b BMA 3   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale15 covale both ? G BMA .   O3  ? ? ? 1_555 G MAN .   C1 ? ? b BMA 3   b MAN 4   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale16 covale both ? G BMA .   O6  ? ? ? 1_555 G MAN .   C1 ? ? b BMA 3   b MAN 5   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale17 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale18 covale both ? I NAG .   O4  ? ? ? 1_555 I NAG .   C1 ? ? c NAG 1   c NAG 2   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
covale19 covale both ? I NAG .   O4  ? ? ? 1_555 I BMA .   C1 ? ? c NAG 2   c BMA 3   1_555 ? ? ? ? ? ? ? 1.447 ? ?               
covale20 covale both ? I BMA .   O3  ? ? ? 1_555 I MAN .   C1 ? ? c BMA 3   c MAN 4   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale21 covale both ? I BMA .   O6  ? ? ? 1_555 I MAN .   C1 ? ? c BMA 3   c MAN 5   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale22 covale both ? J NAG .   O4  ? ? ? 1_555 J NAG .   C1 ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale23 covale both ? K NAG .   O4  ? ? ? 1_555 K NAG .   C1 ? ? d NAG 1   d NAG 2   1_555 ? ? ? ? ? ? ? 1.448 ? ?               
covale24 covale both ? K NAG .   O4  ? ? ? 1_555 K BMA .   C1 ? ? d NAG 2   d BMA 3   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale25 covale both ? K BMA .   O3  ? ? ? 1_555 K MAN .   C1 ? ? d BMA 3   d MAN 4   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale26 covale both ? K BMA .   O6  ? ? ? 1_555 K MAN .   C1 ? ? d BMA 3   d MAN 5   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
covale27 covale both ? L NAG .   O4  ? ? ? 1_555 L NAG .   C1 ? ? e NAG 1   e NAG 2   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale28 covale both ? L NAG .   O4  ? ? ? 1_555 L BMA .   C1 ? ? e NAG 2   e BMA 3   1_555 ? ? ? ? ? ? ? 1.446 ? ?               
covale29 covale both ? L BMA .   O3  ? ? ? 1_555 L MAN .   C1 ? ? e BMA 3   e MAN 4   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
covale30 covale both ? L BMA .   O6  ? ? ? 1_555 L MAN .   C1 ? ? e BMA 3   e MAN 5   1_555 ? ? ? ? ? ? ? 1.446 ? ?               
covale31 covale both ? M NAG .   O4  ? ? ? 1_555 M NAG .   C1 ? ? H NAG 1   H NAG 2   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG F .   ? ASN A 146 ? NAG a 1   ? 1_555 ASN A 111 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG G .   ? ASN B 174 ? NAG b 1   ? 1_555 ASN B 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG H .   ? ASN B 105 ? NAG F 1   ? 1_555 ASN B 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG I .   ? ASN C 174 ? NAG c 1   ? 1_555 ASN C 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG J .   ? ASN C 105 ? NAG G 1   ? 1_555 ASN C 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG K .   ? ASN D 146 ? NAG d 1   ? 1_555 ASN D 111 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG L .   ? ASN E 174 ? NAG e 1   ? 1_555 ASN E 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG M .   ? ASN E 105 ? NAG H 1   ? 1_555 ASN E 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  CYS A 174 ? CYS A 188 ? CYS A 139 ? 1_555 CYS A 153 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS B 161 ? CYS B 175 ? CYS B 136 ? 1_555 CYS B 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS C 161 ? CYS C 175 ? CYS C 136 ? 1_555 CYS C 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS D 174 ? CYS D 188 ? CYS D 139 ? 1_555 CYS D 153 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS E 161 ? CYS E 175 ? CYS E 136 ? 1_555 CYS E 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1  MET 147 A . ? MET 112 A THR 148 A ? THR 113 A 1 -7.64 
2  PHE 181 A . ? PHE 146 A PRO 182 A ? PRO 147 A 1 3.43  
3  VAL 134 B . ? VAL 109 B THR 135 B ? THR 110 B 1 -0.63 
4  TYR 168 B . ? TYR 143 B PRO 169 B ? PRO 144 B 1 4.00  
5  VAL 134 C . ? VAL 109 C THR 135 C ? THR 110 C 1 -1.80 
6  TYR 168 C . ? TYR 143 C PRO 169 C ? PRO 144 C 1 5.34  
7  MET 147 D . ? MET 112 D THR 148 D ? THR 113 D 1 -4.01 
8  PHE 181 D . ? PHE 146 D PRO 182 D ? PRO 147 D 1 4.40  
9  VAL 134 E . ? VAL 109 E THR 135 E ? THR 110 E 1 -0.56 
10 TYR 168 E . ? TYR 143 E PRO 169 E ? PRO 144 E 1 2.56  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 9 ? 
AA2 ? 4 ? 
AA3 ? 9 ? 
AA4 ? 4 ? 
AA5 ? 8 ? 
AA6 ? 4 ? 
AA7 ? 9 ? 
AA8 ? 4 ? 
AA9 ? 9 ? 
AB1 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 3 ? anti-parallel 
AA1 1 8 ? parallel      
AA1 1 9 ? parallel      
AA1 2 3 ? anti-parallel 
AA1 3 7 ? anti-parallel 
AA1 4 6 ? anti-parallel 
AA1 5 7 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 3 ? anti-parallel 
AA3 1 8 ? parallel      
AA3 1 9 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 7 ? anti-parallel 
AA3 4 6 ? anti-parallel 
AA3 5 7 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 1 7 ? parallel      
AA5 1 8 ? parallel      
AA5 2 6 ? anti-parallel 
AA5 3 5 ? anti-parallel 
AA5 4 6 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 3 ? anti-parallel 
AA7 1 8 ? parallel      
AA7 1 9 ? parallel      
AA7 2 3 ? anti-parallel 
AA7 3 7 ? anti-parallel 
AA7 4 6 ? anti-parallel 
AA7 5 7 ? anti-parallel 
AA7 6 7 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 3 ? anti-parallel 
AA9 1 8 ? parallel      
AA9 1 9 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 7 ? anti-parallel 
AA9 4 6 ? anti-parallel 
AA9 5 7 ? anti-parallel 
AA9 6 7 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 74  ? SER A 84  ? THR A 39  SER A 49  
AA1 2 VAL A 88  ? SER A 89  ? VAL A 53  SER A 54  
AA1 3 GLU A 94  ? LYS A 106 ? GLU A 59  LYS A 71  
AA1 4 VAL A 118 ? ARG A 120 ? VAL A 83  ARG A 85  
AA1 5 VAL A 143 ? ALA A 144 ? VAL A 108 ALA A 109 
AA1 6 LYS A 152 ? THR A 157 ? LYS A 117 THR A 122 
AA1 7 THR A 161 ? GLU A 173 ? THR A 126 GLU A 138 
AA1 8 VAL A 202 ? TRP A 206 ? VAL A 167 TRP A 171 
AA1 9 VAL A 214 ? VAL A 216 ? VAL A 179 VAL A 181 
AA2 1 THR A 134 ? PHE A 136 ? THR A 99  PHE A 101 
AA2 2 ALA A 185 ? SER A 194 ? ALA A 150 SER A 159 
AA2 3 GLY A 243 ? ARG A 256 ? GLY A 208 ARG A 221 
AA2 4 TYR A 226 ? SER A 240 ? TYR A 191 SER A 205 
AA3 1 VAL B 61  ? SER B 71  ? VAL B 36  SER B 46  
AA3 2 VAL B 75  ? SER B 76  ? VAL B 50  SER B 51  
AA3 3 ASP B 81  ? ARG B 93  ? ASP B 56  ARG B 68  
AA3 4 THR B 107 ? LEU B 108 ? THR B 82  LEU B 83  
AA3 5 ASP B 126 ? VAL B 131 ? ASP B 101 VAL B 106 
AA3 6 ARG B 139 ? LEU B 143 ? ARG B 114 LEU B 118 
AA3 7 THR B 148 ? ALA B 160 ? THR B 123 ALA B 135 
AA3 8 ILE B 189 ? TRP B 193 ? ILE B 164 TRP B 168 
AA3 9 VAL B 200 ? THR B 201 ? VAL B 175 THR B 176 
AA4 1 THR B 121 ? PHE B 123 ? THR B 96  PHE B 98  
AA4 2 GLU B 172 ? SER B 181 ? GLU B 147 SER B 156 
AA4 3 ALA B 229 ? LYS B 240 ? ALA B 204 LYS B 215 
AA4 4 ILE B 213 ? VAL B 224 ? ILE B 188 VAL B 199 
AA5 1 VAL C 61  ? SER C 76  ? VAL C 36  SER C 51  
AA5 2 ASP C 81  ? ARG C 93  ? ASP C 56  ARG C 68  
AA5 3 THR C 107 ? LEU C 108 ? THR C 82  LEU C 83  
AA5 4 ASP C 126 ? VAL C 131 ? ASP C 101 VAL C 106 
AA5 5 ARG C 139 ? LEU C 143 ? ARG C 114 LEU C 118 
AA5 6 THR C 148 ? ALA C 160 ? THR C 123 ALA C 135 
AA5 7 ILE C 189 ? TRP C 193 ? ILE C 164 TRP C 168 
AA5 8 VAL C 200 ? THR C 201 ? VAL C 175 THR C 176 
AA6 1 THR C 121 ? PHE C 123 ? THR C 96  PHE C 98  
AA6 2 GLU C 172 ? SER C 181 ? GLU C 147 SER C 156 
AA6 3 GLY C 228 ? ARG C 241 ? GLY C 203 ARG C 216 
AA6 4 PHE C 211 ? PHE C 225 ? PHE C 186 PHE C 200 
AA7 1 THR D 74  ? SER D 84  ? THR D 39  SER D 49  
AA7 2 VAL D 88  ? SER D 89  ? VAL D 53  SER D 54  
AA7 3 GLU D 94  ? LYS D 106 ? GLU D 59  LYS D 71  
AA7 4 VAL D 118 ? LEU D 121 ? VAL D 83  LEU D 86  
AA7 5 GLY D 139 ? ALA D 144 ? GLY D 104 ALA D 109 
AA7 6 LYS D 152 ? THR D 157 ? LYS D 117 THR D 122 
AA7 7 THR D 161 ? GLU D 173 ? THR D 126 GLU D 138 
AA7 8 VAL D 202 ? TRP D 206 ? VAL D 167 TRP D 171 
AA7 9 VAL D 214 ? VAL D 216 ? VAL D 179 VAL D 181 
AA8 1 THR D 134 ? PHE D 136 ? THR D 99  PHE D 101 
AA8 2 ALA D 185 ? SER D 194 ? ALA D 150 SER D 159 
AA8 3 GLU D 244 ? ARG D 256 ? GLU D 209 ARG D 221 
AA8 4 TYR D 226 ? GLN D 239 ? TYR D 191 GLN D 204 
AA9 1 VAL E 61  ? SER E 71  ? VAL E 36  SER E 46  
AA9 2 VAL E 75  ? SER E 76  ? VAL E 50  SER E 51  
AA9 3 ASP E 81  ? ARG E 93  ? ASP E 56  ARG E 68  
AA9 4 LEU E 106 ? LEU E 108 ? LEU E 81  LEU E 83  
AA9 5 ASP E 126 ? VAL E 131 ? ASP E 101 VAL E 106 
AA9 6 ARG E 139 ? LEU E 143 ? ARG E 114 LEU E 118 
AA9 7 THR E 148 ? ALA E 160 ? THR E 123 ALA E 135 
AA9 8 ILE E 189 ? TRP E 193 ? ILE E 164 TRP E 168 
AA9 9 VAL E 200 ? THR E 201 ? VAL E 175 THR E 176 
AB1 1 THR E 121 ? PHE E 123 ? THR E 96  PHE E 98  
AB1 2 GLU E 172 ? SER E 181 ? GLU E 147 SER E 156 
AB1 3 GLY E 228 ? ARG E 241 ? GLY E 203 ARG E 216 
AB1 4 PHE E 211 ? PHE E 225 ? PHE E 186 PHE E 200 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 3 N LYS A 77  ? N LYS A 42  O SER A 104 ? O SER A 69  
AA1 1 8 N THR A 78  ? N THR A 43  O GLU A 205 ? O GLU A 170 
AA1 1 9 N VAL A 82  ? N VAL A 47  O VAL A 215 ? O VAL A 180 
AA1 2 3 N SER A 89  ? N SER A 54  O GLU A 94  ? O GLU A 59  
AA1 3 7 N GLN A 103 ? N GLN A 68  O TYR A 164 ? O TYR A 129 
AA1 4 6 N LEU A 119 ? N LEU A 84  O ILE A 156 ? O ILE A 121 
AA1 5 7 N VAL A 143 ? N VAL A 108 O THR A 169 ? O THR A 134 
AA1 6 7 N ARG A 155 ? N ARG A 120 O LEU A 163 ? O LEU A 128 
AA2 1 2 N PHE A 135 ? N PHE A 100 O GLY A 193 ? O GLY A 158 
AA2 2 3 N HIS A 186 ? N HIS A 151 O LEU A 254 ? O LEU A 219 
AA2 3 4 O TYR A 245 ? O TYR A 210 N VAL A 238 ? N VAL A 203 
AA3 1 3 N GLY B 64  ? N GLY B 39  O TYR B 91  ? O TYR B 66  
AA3 1 8 N VAL B 63  ? N VAL B 38  O GLU B 190 ? O GLU B 165 
AA3 1 9 N ILE B 69  ? N ILE B 44  O THR B 201 ? O THR B 176 
AA3 2 3 N SER B 76  ? N SER B 51  O ASP B 81  ? O ASP B 56  
AA3 3 7 N PHE B 88  ? N PHE B 63  O LEU B 153 ? O LEU B 128 
AA3 4 6 N LEU B 108 ? N LEU B 83  O ILE B 141 ? O ILE B 116 
AA3 5 7 N LYS B 127 ? N LYS B 102 O THR B 158 ? O THR B 133 
AA3 6 7 N MET B 140 ? N MET B 115 O GLY B 152 ? O GLY B 127 
AA4 1 2 N TYR B 122 ? N TYR B 97  O GLU B 180 ? O GLU B 155 
AA4 2 3 N ILE B 179 ? N ILE B 154 O LEU B 233 ? O LEU B 208 
AA4 3 4 O TYR B 230 ? O TYR B 205 N VAL B 223 ? N VAL B 198 
AA5 1 2 N GLY C 64  ? N GLY C 39  O TYR C 91  ? O TYR C 66  
AA5 1 7 N VAL C 63  ? N VAL C 38  O GLU C 190 ? O GLU C 165 
AA5 1 8 N ILE C 69  ? N ILE C 44  O THR C 201 ? O THR C 176 
AA5 2 6 N PHE C 88  ? N PHE C 63  O LEU C 153 ? O LEU C 128 
AA5 3 5 N LEU C 108 ? N LEU C 83  O ILE C 141 ? O ILE C 116 
AA5 4 6 N LYS C 128 ? N LYS C 103 O THR C 158 ? O THR C 133 
AA5 5 6 N MET C 140 ? N MET C 115 O GLY C 152 ? O GLY C 127 
AA6 1 2 N TYR C 122 ? N TYR C 97  O GLU C 180 ? O GLU C 155 
AA6 2 3 N ILE C 179 ? N ILE C 154 O LEU C 233 ? O LEU C 208 
AA6 3 4 O GLY C 228 ? O GLY C 203 N PHE C 225 ? N PHE C 200 
AA7 1 3 N LYS D 77  ? N LYS D 42  O SER D 104 ? O SER D 69  
AA7 1 8 N THR D 78  ? N THR D 43  O GLU D 205 ? O GLU D 170 
AA7 1 9 N VAL D 82  ? N VAL D 47  O VAL D 215 ? O VAL D 180 
AA7 2 3 N SER D 89  ? N SER D 54  O GLU D 94  ? O GLU D 59  
AA7 3 7 N TRP D 105 ? N TRP D 70  O LEU D 162 ? O LEU D 127 
AA7 4 6 N LEU D 121 ? N LEU D 86  O LEU D 154 ? O LEU D 119 
AA7 5 7 N VAL D 143 ? N VAL D 108 O THR D 169 ? O THR D 134 
AA7 6 7 N ARG D 155 ? N ARG D 120 O LEU D 163 ? O LEU D 128 
AA8 1 2 N PHE D 135 ? N PHE D 100 O GLY D 193 ? O GLY D 158 
AA8 2 3 N HIS D 186 ? N HIS D 151 O LEU D 254 ? O LEU D 219 
AA8 3 4 O VAL D 247 ? O VAL D 212 N GLY D 236 ? N GLY D 201 
AA9 1 3 N ASP E 68  ? N ASP E 43  O TYR E 87  ? O TYR E 62  
AA9 1 8 N VAL E 63  ? N VAL E 38  O GLU E 190 ? O GLU E 165 
AA9 1 9 N ILE E 69  ? N ILE E 44  O THR E 201 ? O THR E 176 
AA9 2 3 N SER E 76  ? N SER E 51  O ASP E 81  ? O ASP E 56  
AA9 3 7 N PHE E 88  ? N PHE E 63  O LEU E 153 ? O LEU E 128 
AA9 4 6 N LEU E 108 ? N LEU E 83  O ILE E 141 ? O ILE E 116 
AA9 5 7 N LYS E 127 ? N LYS E 102 O THR E 158 ? O THR E 133 
AA9 6 7 N MET E 140 ? N MET E 115 O GLY E 152 ? O GLY E 127 
AB1 1 2 N TYR E 122 ? N TYR E 97  O GLU E 180 ? O GLU E 155 
AB1 2 3 N ILE E 179 ? N ILE E 154 O LEU E 233 ? O LEU E 208 
AB1 3 4 O TYR E 230 ? O TYR E 205 N VAL E 223 ? N VAL E 198 
# 
_pdbx_entry_details.entry_id                   9FG4 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER A 49  ? ? -161.73 117.29  
2  1 ASP A 98  ? ? -90.94  58.69   
3  1 LEU A 143 ? ? -98.78  31.36   
4  1 MET A 148 ? ? -107.78 41.03   
5  1 ARG A 173 ? ? -127.65 -166.44 
6  1 ASP A 184 ? ? -98.65  31.03   
7  1 ARG A 187 ? ? -109.86 41.06   
8  1 PRO B 78  ? ? -81.27  46.04   
9  1 LEU B 145 ? ? -97.07  32.22   
10 1 LYS B 274 ? ? -68.07  66.69   
11 1 PRO C 78  ? ? -83.82  46.30   
12 1 LEU C 145 ? ? -92.35  30.54   
13 1 LYS C 274 ? ? -67.88  64.76   
14 1 PHE C 306 ? ? -92.77  -61.24  
15 1 LYS D 106 ? ? -161.22 114.01  
16 1 ARG D 173 ? ? -127.28 -167.70 
17 1 PRO E 78  ? ? -77.83  48.03   
18 1 PHE E 306 ? ? -94.33  -61.89  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9FG4 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   'FSC at 0.5' 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   30 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      OTHER 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  6HUK 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                6HUK 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    9FG4 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               52000 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '137 mM NaCl, 2.7 mM KCl, 4.3 mM Na2HPO' 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in the long-lived symmetric resting state' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_image_scans.entry_id                9FG4 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        4096 
_em_image_scans.dimension_width         4096 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9FG4 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1400 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           96000 
_em_imaging.calibrated_magnification        96000 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    ? 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        'UltrAuFoil R1.2/1.3' 
_em_sample_support.details          'current: 30mA' 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9FG4 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   281 
_em_vitrification.instrument            'HOMEMADE PLUNGER' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9FG4 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9FG4 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -34 ? A MET 1   
2   1 Y 1 A LYS -33 ? A LYS 2   
3   1 Y 1 A LYS -32 ? A LYS 3   
4   1 Y 1 A SER -31 ? A SER 4   
5   1 Y 1 A PRO -30 ? A PRO 5   
6   1 Y 1 A GLY -29 ? A GLY 6   
7   1 Y 1 A LEU -28 ? A LEU 7   
8   1 Y 1 A SER -27 ? A SER 8   
9   1 Y 1 A ASP -26 ? A ASP 9   
10  1 Y 1 A TYR -25 ? A TYR 10  
11  1 Y 1 A LEU -24 ? A LEU 11  
12  1 Y 1 A TRP -23 ? A TRP 12  
13  1 Y 1 A ALA -22 ? A ALA 13  
14  1 Y 1 A TRP -21 ? A TRP 14  
15  1 Y 1 A THR -20 ? A THR 15  
16  1 Y 1 A LEU -19 ? A LEU 16  
17  1 Y 1 A PHE -18 ? A PHE 17  
18  1 Y 1 A LEU -17 ? A LEU 18  
19  1 Y 1 A SER -16 ? A SER 19  
20  1 Y 1 A THR -15 ? A THR 20  
21  1 Y 1 A LEU -14 ? A LEU 21  
22  1 Y 1 A THR -13 ? A THR 22  
23  1 Y 1 A GLY -12 ? A GLY 23  
24  1 Y 1 A ARG -11 ? A ARG 24  
25  1 Y 1 A SER -10 ? A SER 25  
26  1 Y 1 A TYR -9  ? A TYR 26  
27  1 Y 1 A GLY -8  ? A GLY 27  
28  1 Y 1 A ASP -7  ? A ASP 28  
29  1 Y 1 A TYR -6  ? A TYR 29  
30  1 Y 1 A LYS -5  ? A LYS 30  
31  1 Y 1 A ASP -4  ? A ASP 31  
32  1 Y 1 A ASP -3  ? A ASP 32  
33  1 Y 1 A ASP -2  ? A ASP 33  
34  1 Y 1 A ASP -1  ? A ASP 34  
35  1 Y 1 A LYS 0   ? A LYS 35  
36  1 Y 1 A GLN 1   ? A GLN 36  
37  1 Y 1 A PRO 2   ? A PRO 37  
38  1 Y 1 A SER 3   ? A SER 38  
39  1 Y 1 A LEU 4   ? A LEU 39  
40  1 Y 1 A GLN 5   ? A GLN 40  
41  1 Y 1 A ASP 6   ? A ASP 41  
42  1 Y 1 A GLU 7   ? A GLU 42  
43  1 Y 1 A LEU 8   ? A LEU 43  
44  1 Y 1 A LYS 9   ? A LYS 44  
45  1 Y 1 A ASP 10  ? A ASP 45  
46  1 Y 1 A ASN 11  ? A ASN 46  
47  1 Y 1 A VAL 322 ? A VAL 357 
48  1 Y 1 A VAL 323 ? A VAL 358 
49  1 Y 1 A PRO 324 ? A PRO 359 
50  1 Y 1 A GLU 325 ? A GLU 360 
51  1 Y 1 A LYS 326 ? A LYS 361 
52  1 Y 1 A PRO 327 ? A PRO 362 
53  1 Y 1 A LYS 328 ? A LYS 363 
54  1 Y 1 A LYS 329 ? A LYS 364 
55  1 Y 1 A VAL 330 ? A VAL 365 
56  1 Y 1 A LYS 331 ? A LYS 366 
57  1 Y 1 A ASP 332 ? A ASP 367 
58  1 Y 1 A PRO 333 ? A PRO 368 
59  1 Y 1 A LEU 334 ? A LEU 369 
60  1 Y 1 A ILE 335 ? A ILE 370 
61  1 Y 1 A LYS 336 ? A LYS 371 
62  1 Y 1 A LYS 337 ? A LYS 372 
63  1 Y 1 A ASN 338 ? A ASN 373 
64  1 Y 1 A ASN 339 ? A ASN 374 
65  1 Y 1 A THR 340 ? A THR 375 
66  1 Y 1 A TYR 341 ? A TYR 376 
67  1 Y 1 A ALA 342 ? A ALA 377 
68  1 Y 1 A PRO 343 ? A PRO 378 
69  1 Y 1 A THR 344 ? A THR 379 
70  1 Y 1 A ALA 345 ? A ALA 380 
71  1 Y 1 A THR 346 ? A THR 381 
72  1 Y 1 A SER 347 ? A SER 382 
73  1 Y 1 A TYR 348 ? A TYR 383 
74  1 Y 1 A THR 349 ? A THR 384 
75  1 Y 1 A PRO 350 ? A PRO 385 
76  1 Y 1 A ASN 351 ? A ASN 386 
77  1 Y 1 A LEU 352 ? A LEU 387 
78  1 Y 1 A ALA 353 ? A ALA 388 
79  1 Y 1 A ARG 354 ? A ARG 389 
80  1 Y 1 A GLY 355 ? A GLY 390 
81  1 Y 1 A ASP 356 ? A ASP 391 
82  1 Y 1 A PRO 357 ? A PRO 392 
83  1 Y 1 A GLY 358 ? A GLY 393 
84  1 Y 1 A LEU 359 ? A LEU 394 
85  1 Y 1 A ALA 360 ? A ALA 395 
86  1 Y 1 A THR 361 ? A THR 396 
87  1 Y 1 A ILE 362 ? A ILE 397 
88  1 Y 1 A ALA 363 ? A ALA 398 
89  1 Y 1 A LYS 364 ? A LYS 399 
90  1 Y 1 A SER 365 ? A SER 400 
91  1 Y 1 A ALA 366 ? A ALA 401 
92  1 Y 1 A THR 367 ? A THR 402 
93  1 Y 1 A ILE 368 ? A ILE 403 
94  1 Y 1 A GLU 369 ? A GLU 404 
95  1 Y 1 A PRO 370 ? A PRO 405 
96  1 Y 1 A LYS 371 ? A LYS 406 
97  1 Y 1 A GLU 372 ? A GLU 407 
98  1 Y 1 A VAL 373 ? A VAL 408 
99  1 Y 1 A LYS 374 ? A LYS 409 
100 1 Y 1 A PRO 375 ? A PRO 410 
101 1 Y 1 A GLU 376 ? A GLU 411 
102 1 Y 1 A THR 377 ? A THR 412 
103 1 Y 1 A LYS 378 ? A LYS 413 
104 1 Y 1 A PRO 379 ? A PRO 414 
105 1 Y 1 A PRO 380 ? A PRO 415 
106 1 Y 1 A GLU 381 ? A GLU 416 
107 1 Y 1 A PRO 382 ? A PRO 417 
108 1 Y 1 A LYS 383 ? A LYS 418 
109 1 Y 1 A ASN 417 ? A ASN 452 
110 1 Y 1 A ARG 418 ? A ARG 453 
111 1 Y 1 A GLU 419 ? A GLU 454 
112 1 Y 1 A PRO 420 ? A PRO 455 
113 1 Y 1 A GLN 421 ? A GLN 456 
114 1 Y 1 A LEU 422 ? A LEU 457 
115 1 Y 1 A LYS 423 ? A LYS 458 
116 1 Y 1 A ALA 424 ? A ALA 459 
117 1 Y 1 A PRO 425 ? A PRO 460 
118 1 Y 1 A THR 426 ? A THR 461 
119 1 Y 1 A PRO 427 ? A PRO 462 
120 1 Y 1 A HIS 428 ? A HIS 463 
121 1 Y 1 A GLN 429 ? A GLN 464 
122 1 Y 1 B MET -24 ? B MET 1   
123 1 Y 1 B CYS -23 ? B CYS 2   
124 1 Y 1 B SER -22 ? B SER 3   
125 1 Y 1 B GLY -21 ? B GLY 4   
126 1 Y 1 B LEU -20 ? B LEU 5   
127 1 Y 1 B LEU -19 ? B LEU 6   
128 1 Y 1 B GLU -18 ? B GLU 7   
129 1 Y 1 B LEU -17 ? B LEU 8   
130 1 Y 1 B LEU -16 ? B LEU 9   
131 1 Y 1 B LEU -15 ? B LEU 10  
132 1 Y 1 B PRO -14 ? B PRO 11  
133 1 Y 1 B ILE -13 ? B ILE 12  
134 1 Y 1 B TRP -12 ? B TRP 13  
135 1 Y 1 B LEU -11 ? B LEU 14  
136 1 Y 1 B SER -10 ? B SER 15  
137 1 Y 1 B TRP -9  ? B TRP 16  
138 1 Y 1 B THR -8  ? B THR 17  
139 1 Y 1 B LEU -7  ? B LEU 18  
140 1 Y 1 B GLY -6  ? B GLY 19  
141 1 Y 1 B THR -5  ? B THR 20  
142 1 Y 1 B ARG -4  ? B ARG 21  
143 1 Y 1 B GLY -3  ? B GLY 22  
144 1 Y 1 B SER -2  ? B SER 23  
145 1 Y 1 B GLU -1  ? B GLU 24  
146 1 Y 1 B PRO 0   ? B PRO 25  
147 1 Y 1 B ARG 1   ? B ARG 26  
148 1 Y 1 B SER 2   ? B SER 27  
149 1 Y 1 B VAL 3   ? B VAL 28  
150 1 Y 1 B ASN 4   ? B ASN 29  
151 1 Y 1 B ASP 5   ? B ASP 30  
152 1 Y 1 B PRO 6   ? B PRO 31  
153 1 Y 1 B GLY 7   ? B GLY 32  
154 1 Y 1 B ASN 8   ? B ASN 33  
155 1 Y 1 B GLY 335 ? B GLY 335 
156 1 Y 1 B PRO 336 ? B PRO 336 
157 1 Y 1 B GLN 337 ? B GLN 337 
158 1 Y 1 B ARG 338 ? B ARG 338 
159 1 Y 1 B GLN 339 ? B GLN 339 
160 1 Y 1 B LYS 340 ? B LYS 340 
161 1 Y 1 B LYS 341 ? B LYS 341 
162 1 Y 1 B LEU 342 ? B LEU 342 
163 1 Y 1 B ALA 343 ? B ALA 343 
164 1 Y 1 B GLU 344 ? B GLU 344 
165 1 Y 1 B LYS 345 ? B LYS 345 
166 1 Y 1 B THR 346 ? B THR 346 
167 1 Y 1 B ALA 347 ? B ALA 347 
168 1 Y 1 B LYS 348 ? B LYS 348 
169 1 Y 1 B ALA 349 ? B ALA 349 
170 1 Y 1 B LYS 350 ? B LYS 350 
171 1 Y 1 B ASN 351 ? B ASN 351 
172 1 Y 1 B ASP 352 ? B ASP 352 
173 1 Y 1 B ARG 353 ? B ARG 353 
174 1 Y 1 B SER 354 ? B SER 354 
175 1 Y 1 B LYS 355 ? B LYS 355 
176 1 Y 1 B SER 356 ? B SER 356 
177 1 Y 1 B GLU 357 ? B GLU 357 
178 1 Y 1 B SER 358 ? B SER 358 
179 1 Y 1 B ASN 359 ? B ASN 359 
180 1 Y 1 B ARG 360 ? B ARG 360 
181 1 Y 1 B VAL 361 ? B VAL 361 
182 1 Y 1 B ASP 362 ? B ASP 362 
183 1 Y 1 B ALA 363 ? B ALA 363 
184 1 Y 1 B HIS 364 ? B HIS 364 
185 1 Y 1 B GLY 365 ? B GLY 365 
186 1 Y 1 B ASN 366 ? B ASN 366 
187 1 Y 1 B ILE 367 ? B ILE 367 
188 1 Y 1 B LEU 368 ? B LEU 368 
189 1 Y 1 B LEU 369 ? B LEU 369 
190 1 Y 1 B THR 370 ? B THR 370 
191 1 Y 1 B SER 371 ? B SER 371 
192 1 Y 1 B LEU 372 ? B LEU 372 
193 1 Y 1 B GLU 373 ? B GLU 373 
194 1 Y 1 B VAL 374 ? B VAL 374 
195 1 Y 1 B HIS 375 ? B HIS 375 
196 1 Y 1 B ASN 376 ? B ASN 376 
197 1 Y 1 B GLU 377 ? B GLU 377 
198 1 Y 1 B MET 378 ? B MET 378 
199 1 Y 1 B ASN 379 ? B ASN 379 
200 1 Y 1 B GLU 380 ? B GLU 380 
201 1 Y 1 B VAL 381 ? B VAL 381 
202 1 Y 1 B SER 382 ? B SER 382 
203 1 Y 1 B GLY 383 ? B GLY 383 
204 1 Y 1 B GLY 384 ? B GLY 384 
205 1 Y 1 B ILE 385 ? B ILE 385 
206 1 Y 1 B GLY 386 ? B GLY 386 
207 1 Y 1 B ASP 387 ? B ASP 387 
208 1 Y 1 B THR 388 ? B THR 388 
209 1 Y 1 B ARG 389 ? B ARG 389 
210 1 Y 1 B ASN 390 ? B ASN 390 
211 1 Y 1 B SER 391 ? B SER 391 
212 1 Y 1 B ALA 392 ? B ALA 392 
213 1 Y 1 B ILE 393 ? B ILE 393 
214 1 Y 1 B SER 394 ? B SER 394 
215 1 Y 1 B PHE 395 ? B PHE 395 
216 1 Y 1 B ASP 396 ? B ASP 396 
217 1 Y 1 B ASN 397 ? B ASN 397 
218 1 Y 1 B SER 398 ? B SER 398 
219 1 Y 1 B GLY 399 ? B GLY 399 
220 1 Y 1 B ILE 400 ? B ILE 400 
221 1 Y 1 B GLN 401 ? B GLN 401 
222 1 Y 1 B TYR 402 ? B TYR 402 
223 1 Y 1 B ARG 403 ? B ARG 403 
224 1 Y 1 B LYS 404 ? B LYS 404 
225 1 Y 1 B GLN 405 ? B GLN 405 
226 1 Y 1 B SER 406 ? B SER 406 
227 1 Y 1 B MET 407 ? B MET 407 
228 1 Y 1 B PRO 408 ? B PRO 408 
229 1 Y 1 B ARG 409 ? B ARG 409 
230 1 Y 1 B GLU 410 ? B GLU 410 
231 1 Y 1 B GLY 411 ? B GLY 411 
232 1 Y 1 B HIS 412 ? B HIS 412 
233 1 Y 1 B GLY 413 ? B GLY 413 
234 1 Y 1 B ARG 414 ? B ARG 414 
235 1 Y 1 B PHE 415 ? B PHE 415 
236 1 Y 1 B LEU 416 ? B LEU 416 
237 1 Y 1 B GLY 417 ? B GLY 417 
238 1 Y 1 B ASP 418 ? B ASP 418 
239 1 Y 1 B ARG 419 ? B ARG 419 
240 1 Y 1 B SER 420 ? B SER 420 
241 1 Y 1 B LEU 421 ? B LEU 421 
242 1 Y 1 B PRO 422 ? B PRO 422 
243 1 Y 1 B HIS 423 ? B HIS 423 
244 1 Y 1 B LYS 424 ? B LYS 424 
245 1 Y 1 B LYS 425 ? B LYS 425 
246 1 Y 1 B THR 426 ? B THR 426 
247 1 Y 1 B HIS 427 ? B HIS 427 
248 1 Y 1 B LEU 428 ? B LEU 428 
249 1 Y 1 B ARG 429 ? B ARG 429 
250 1 Y 1 B ARG 430 ? B ARG 430 
251 1 Y 1 B ARG 431 ? B ARG 431 
252 1 Y 1 B SER 432 ? B SER 432 
253 1 Y 1 B SER 433 ? B SER 433 
254 1 Y 1 B GLN 434 ? B GLN 434 
255 1 Y 1 B LEU 435 ? B LEU 435 
256 1 Y 1 B LYS 436 ? B LYS 436 
257 1 Y 1 B ILE 437 ? B ILE 437 
258 1 Y 1 B LYS 438 ? B LYS 438 
259 1 Y 1 B ILE 439 ? B ILE 439 
260 1 Y 1 B PRO 440 ? B PRO 440 
261 1 Y 1 B ASP 441 ? B ASP 441 
262 1 Y 1 B LEU 442 ? B LEU 442 
263 1 Y 1 B THR 443 ? B THR 443 
264 1 Y 1 B ASN 473 ? B ASN 473 
265 1 Y 1 C MET -24 ? C MET 1   
266 1 Y 1 C CYS -23 ? C CYS 2   
267 1 Y 1 C SER -22 ? C SER 3   
268 1 Y 1 C GLY -21 ? C GLY 4   
269 1 Y 1 C LEU -20 ? C LEU 5   
270 1 Y 1 C LEU -19 ? C LEU 6   
271 1 Y 1 C GLU -18 ? C GLU 7   
272 1 Y 1 C LEU -17 ? C LEU 8   
273 1 Y 1 C LEU -16 ? C LEU 9   
274 1 Y 1 C LEU -15 ? C LEU 10  
275 1 Y 1 C PRO -14 ? C PRO 11  
276 1 Y 1 C ILE -13 ? C ILE 12  
277 1 Y 1 C TRP -12 ? C TRP 13  
278 1 Y 1 C LEU -11 ? C LEU 14  
279 1 Y 1 C SER -10 ? C SER 15  
280 1 Y 1 C TRP -9  ? C TRP 16  
281 1 Y 1 C THR -8  ? C THR 17  
282 1 Y 1 C LEU -7  ? C LEU 18  
283 1 Y 1 C GLY -6  ? C GLY 19  
284 1 Y 1 C THR -5  ? C THR 20  
285 1 Y 1 C ARG -4  ? C ARG 21  
286 1 Y 1 C GLY -3  ? C GLY 22  
287 1 Y 1 C SER -2  ? C SER 23  
288 1 Y 1 C GLU -1  ? C GLU 24  
289 1 Y 1 C PRO 0   ? C PRO 25  
290 1 Y 1 C ARG 1   ? C ARG 26  
291 1 Y 1 C SER 2   ? C SER 27  
292 1 Y 1 C VAL 3   ? C VAL 28  
293 1 Y 1 C ASN 4   ? C ASN 29  
294 1 Y 1 C ASP 5   ? C ASP 30  
295 1 Y 1 C PRO 6   ? C PRO 31  
296 1 Y 1 C GLY 7   ? C GLY 32  
297 1 Y 1 C ASN 8   ? C ASN 33  
298 1 Y 1 C GLY 335 ? C GLY 335 
299 1 Y 1 C PRO 336 ? C PRO 336 
300 1 Y 1 C GLN 337 ? C GLN 337 
301 1 Y 1 C ARG 338 ? C ARG 338 
302 1 Y 1 C GLN 339 ? C GLN 339 
303 1 Y 1 C LYS 340 ? C LYS 340 
304 1 Y 1 C LYS 341 ? C LYS 341 
305 1 Y 1 C LEU 342 ? C LEU 342 
306 1 Y 1 C ALA 343 ? C ALA 343 
307 1 Y 1 C GLU 344 ? C GLU 344 
308 1 Y 1 C LYS 345 ? C LYS 345 
309 1 Y 1 C THR 346 ? C THR 346 
310 1 Y 1 C ALA 347 ? C ALA 347 
311 1 Y 1 C LYS 348 ? C LYS 348 
312 1 Y 1 C ALA 349 ? C ALA 349 
313 1 Y 1 C LYS 350 ? C LYS 350 
314 1 Y 1 C ASN 351 ? C ASN 351 
315 1 Y 1 C ASP 352 ? C ASP 352 
316 1 Y 1 C ARG 353 ? C ARG 353 
317 1 Y 1 C SER 354 ? C SER 354 
318 1 Y 1 C LYS 355 ? C LYS 355 
319 1 Y 1 C SER 356 ? C SER 356 
320 1 Y 1 C GLU 357 ? C GLU 357 
321 1 Y 1 C SER 358 ? C SER 358 
322 1 Y 1 C ASN 359 ? C ASN 359 
323 1 Y 1 C ARG 360 ? C ARG 360 
324 1 Y 1 C VAL 361 ? C VAL 361 
325 1 Y 1 C ASP 362 ? C ASP 362 
326 1 Y 1 C ALA 363 ? C ALA 363 
327 1 Y 1 C HIS 364 ? C HIS 364 
328 1 Y 1 C GLY 365 ? C GLY 365 
329 1 Y 1 C ASN 366 ? C ASN 366 
330 1 Y 1 C ILE 367 ? C ILE 367 
331 1 Y 1 C LEU 368 ? C LEU 368 
332 1 Y 1 C LEU 369 ? C LEU 369 
333 1 Y 1 C THR 370 ? C THR 370 
334 1 Y 1 C SER 371 ? C SER 371 
335 1 Y 1 C LEU 372 ? C LEU 372 
336 1 Y 1 C GLU 373 ? C GLU 373 
337 1 Y 1 C VAL 374 ? C VAL 374 
338 1 Y 1 C HIS 375 ? C HIS 375 
339 1 Y 1 C ASN 376 ? C ASN 376 
340 1 Y 1 C GLU 377 ? C GLU 377 
341 1 Y 1 C MET 378 ? C MET 378 
342 1 Y 1 C ASN 379 ? C ASN 379 
343 1 Y 1 C GLU 380 ? C GLU 380 
344 1 Y 1 C VAL 381 ? C VAL 381 
345 1 Y 1 C SER 382 ? C SER 382 
346 1 Y 1 C GLY 383 ? C GLY 383 
347 1 Y 1 C GLY 384 ? C GLY 384 
348 1 Y 1 C ILE 385 ? C ILE 385 
349 1 Y 1 C GLY 386 ? C GLY 386 
350 1 Y 1 C ASP 387 ? C ASP 387 
351 1 Y 1 C THR 388 ? C THR 388 
352 1 Y 1 C ARG 389 ? C ARG 389 
353 1 Y 1 C ASN 390 ? C ASN 390 
354 1 Y 1 C SER 391 ? C SER 391 
355 1 Y 1 C ALA 392 ? C ALA 392 
356 1 Y 1 C ILE 393 ? C ILE 393 
357 1 Y 1 C SER 394 ? C SER 394 
358 1 Y 1 C PHE 395 ? C PHE 395 
359 1 Y 1 C ASP 396 ? C ASP 396 
360 1 Y 1 C ASN 397 ? C ASN 397 
361 1 Y 1 C SER 398 ? C SER 398 
362 1 Y 1 C GLY 399 ? C GLY 399 
363 1 Y 1 C ILE 400 ? C ILE 400 
364 1 Y 1 C GLN 401 ? C GLN 401 
365 1 Y 1 C TYR 402 ? C TYR 402 
366 1 Y 1 C ARG 403 ? C ARG 403 
367 1 Y 1 C LYS 404 ? C LYS 404 
368 1 Y 1 C GLN 405 ? C GLN 405 
369 1 Y 1 C SER 406 ? C SER 406 
370 1 Y 1 C MET 407 ? C MET 407 
371 1 Y 1 C PRO 408 ? C PRO 408 
372 1 Y 1 C ARG 409 ? C ARG 409 
373 1 Y 1 C GLU 410 ? C GLU 410 
374 1 Y 1 C GLY 411 ? C GLY 411 
375 1 Y 1 C HIS 412 ? C HIS 412 
376 1 Y 1 C GLY 413 ? C GLY 413 
377 1 Y 1 C ARG 414 ? C ARG 414 
378 1 Y 1 C PHE 415 ? C PHE 415 
379 1 Y 1 C LEU 416 ? C LEU 416 
380 1 Y 1 C GLY 417 ? C GLY 417 
381 1 Y 1 C ASP 418 ? C ASP 418 
382 1 Y 1 C ARG 419 ? C ARG 419 
383 1 Y 1 C SER 420 ? C SER 420 
384 1 Y 1 C LEU 421 ? C LEU 421 
385 1 Y 1 C PRO 422 ? C PRO 422 
386 1 Y 1 C HIS 423 ? C HIS 423 
387 1 Y 1 C LYS 424 ? C LYS 424 
388 1 Y 1 C LYS 425 ? C LYS 425 
389 1 Y 1 C THR 426 ? C THR 426 
390 1 Y 1 C HIS 427 ? C HIS 427 
391 1 Y 1 C LEU 428 ? C LEU 428 
392 1 Y 1 C ARG 429 ? C ARG 429 
393 1 Y 1 C ARG 430 ? C ARG 430 
394 1 Y 1 C ARG 431 ? C ARG 431 
395 1 Y 1 C SER 432 ? C SER 432 
396 1 Y 1 C SER 433 ? C SER 433 
397 1 Y 1 C GLN 434 ? C GLN 434 
398 1 Y 1 C LEU 435 ? C LEU 435 
399 1 Y 1 C LYS 436 ? C LYS 436 
400 1 Y 1 C ILE 437 ? C ILE 437 
401 1 Y 1 C LYS 438 ? C LYS 438 
402 1 Y 1 C ILE 439 ? C ILE 439 
403 1 Y 1 C PRO 440 ? C PRO 440 
404 1 Y 1 C ASP 441 ? C ASP 441 
405 1 Y 1 C LEU 442 ? C LEU 442 
406 1 Y 1 C THR 443 ? C THR 443 
407 1 Y 1 C ASN 473 ? C ASN 473 
408 1 Y 1 D MET -34 ? D MET 1   
409 1 Y 1 D LYS -33 ? D LYS 2   
410 1 Y 1 D LYS -32 ? D LYS 3   
411 1 Y 1 D SER -31 ? D SER 4   
412 1 Y 1 D PRO -30 ? D PRO 5   
413 1 Y 1 D GLY -29 ? D GLY 6   
414 1 Y 1 D LEU -28 ? D LEU 7   
415 1 Y 1 D SER -27 ? D SER 8   
416 1 Y 1 D ASP -26 ? D ASP 9   
417 1 Y 1 D TYR -25 ? D TYR 10  
418 1 Y 1 D LEU -24 ? D LEU 11  
419 1 Y 1 D TRP -23 ? D TRP 12  
420 1 Y 1 D ALA -22 ? D ALA 13  
421 1 Y 1 D TRP -21 ? D TRP 14  
422 1 Y 1 D THR -20 ? D THR 15  
423 1 Y 1 D LEU -19 ? D LEU 16  
424 1 Y 1 D PHE -18 ? D PHE 17  
425 1 Y 1 D LEU -17 ? D LEU 18  
426 1 Y 1 D SER -16 ? D SER 19  
427 1 Y 1 D THR -15 ? D THR 20  
428 1 Y 1 D LEU -14 ? D LEU 21  
429 1 Y 1 D THR -13 ? D THR 22  
430 1 Y 1 D GLY -12 ? D GLY 23  
431 1 Y 1 D ARG -11 ? D ARG 24  
432 1 Y 1 D SER -10 ? D SER 25  
433 1 Y 1 D TYR -9  ? D TYR 26  
434 1 Y 1 D GLY -8  ? D GLY 27  
435 1 Y 1 D ASP -7  ? D ASP 28  
436 1 Y 1 D TYR -6  ? D TYR 29  
437 1 Y 1 D LYS -5  ? D LYS 30  
438 1 Y 1 D ASP -4  ? D ASP 31  
439 1 Y 1 D ASP -3  ? D ASP 32  
440 1 Y 1 D ASP -2  ? D ASP 33  
441 1 Y 1 D ASP -1  ? D ASP 34  
442 1 Y 1 D LYS 0   ? D LYS 35  
443 1 Y 1 D GLN 1   ? D GLN 36  
444 1 Y 1 D PRO 2   ? D PRO 37  
445 1 Y 1 D SER 3   ? D SER 38  
446 1 Y 1 D LEU 4   ? D LEU 39  
447 1 Y 1 D GLN 5   ? D GLN 40  
448 1 Y 1 D ASP 6   ? D ASP 41  
449 1 Y 1 D GLU 7   ? D GLU 42  
450 1 Y 1 D LEU 8   ? D LEU 43  
451 1 Y 1 D LYS 9   ? D LYS 44  
452 1 Y 1 D ASP 10  ? D ASP 45  
453 1 Y 1 D ASN 11  ? D ASN 46  
454 1 Y 1 D VAL 322 ? D VAL 357 
455 1 Y 1 D VAL 323 ? D VAL 358 
456 1 Y 1 D PRO 324 ? D PRO 359 
457 1 Y 1 D GLU 325 ? D GLU 360 
458 1 Y 1 D LYS 326 ? D LYS 361 
459 1 Y 1 D PRO 327 ? D PRO 362 
460 1 Y 1 D LYS 328 ? D LYS 363 
461 1 Y 1 D LYS 329 ? D LYS 364 
462 1 Y 1 D VAL 330 ? D VAL 365 
463 1 Y 1 D LYS 331 ? D LYS 366 
464 1 Y 1 D ASP 332 ? D ASP 367 
465 1 Y 1 D PRO 333 ? D PRO 368 
466 1 Y 1 D LEU 334 ? D LEU 369 
467 1 Y 1 D ILE 335 ? D ILE 370 
468 1 Y 1 D LYS 336 ? D LYS 371 
469 1 Y 1 D LYS 337 ? D LYS 372 
470 1 Y 1 D ASN 338 ? D ASN 373 
471 1 Y 1 D ASN 339 ? D ASN 374 
472 1 Y 1 D THR 340 ? D THR 375 
473 1 Y 1 D TYR 341 ? D TYR 376 
474 1 Y 1 D ALA 342 ? D ALA 377 
475 1 Y 1 D PRO 343 ? D PRO 378 
476 1 Y 1 D THR 344 ? D THR 379 
477 1 Y 1 D ALA 345 ? D ALA 380 
478 1 Y 1 D THR 346 ? D THR 381 
479 1 Y 1 D SER 347 ? D SER 382 
480 1 Y 1 D TYR 348 ? D TYR 383 
481 1 Y 1 D THR 349 ? D THR 384 
482 1 Y 1 D PRO 350 ? D PRO 385 
483 1 Y 1 D ASN 351 ? D ASN 386 
484 1 Y 1 D LEU 352 ? D LEU 387 
485 1 Y 1 D ALA 353 ? D ALA 388 
486 1 Y 1 D ARG 354 ? D ARG 389 
487 1 Y 1 D GLY 355 ? D GLY 390 
488 1 Y 1 D ASP 356 ? D ASP 391 
489 1 Y 1 D PRO 357 ? D PRO 392 
490 1 Y 1 D GLY 358 ? D GLY 393 
491 1 Y 1 D LEU 359 ? D LEU 394 
492 1 Y 1 D ALA 360 ? D ALA 395 
493 1 Y 1 D THR 361 ? D THR 396 
494 1 Y 1 D ILE 362 ? D ILE 397 
495 1 Y 1 D ALA 363 ? D ALA 398 
496 1 Y 1 D LYS 364 ? D LYS 399 
497 1 Y 1 D SER 365 ? D SER 400 
498 1 Y 1 D ALA 366 ? D ALA 401 
499 1 Y 1 D THR 367 ? D THR 402 
500 1 Y 1 D ILE 368 ? D ILE 403 
501 1 Y 1 D GLU 369 ? D GLU 404 
502 1 Y 1 D PRO 370 ? D PRO 405 
503 1 Y 1 D LYS 371 ? D LYS 406 
504 1 Y 1 D GLU 372 ? D GLU 407 
505 1 Y 1 D VAL 373 ? D VAL 408 
506 1 Y 1 D LYS 374 ? D LYS 409 
507 1 Y 1 D PRO 375 ? D PRO 410 
508 1 Y 1 D GLU 376 ? D GLU 411 
509 1 Y 1 D THR 377 ? D THR 412 
510 1 Y 1 D LYS 378 ? D LYS 413 
511 1 Y 1 D PRO 379 ? D PRO 414 
512 1 Y 1 D PRO 380 ? D PRO 415 
513 1 Y 1 D GLU 381 ? D GLU 416 
514 1 Y 1 D PRO 382 ? D PRO 417 
515 1 Y 1 D LYS 383 ? D LYS 418 
516 1 Y 1 D ASN 417 ? D ASN 452 
517 1 Y 1 D ARG 418 ? D ARG 453 
518 1 Y 1 D GLU 419 ? D GLU 454 
519 1 Y 1 D PRO 420 ? D PRO 455 
520 1 Y 1 D GLN 421 ? D GLN 456 
521 1 Y 1 D LEU 422 ? D LEU 457 
522 1 Y 1 D LYS 423 ? D LYS 458 
523 1 Y 1 D ALA 424 ? D ALA 459 
524 1 Y 1 D PRO 425 ? D PRO 460 
525 1 Y 1 D THR 426 ? D THR 461 
526 1 Y 1 D PRO 427 ? D PRO 462 
527 1 Y 1 D HIS 428 ? D HIS 463 
528 1 Y 1 D GLN 429 ? D GLN 464 
529 1 Y 1 E MET -24 ? E MET 1   
530 1 Y 1 E CYS -23 ? E CYS 2   
531 1 Y 1 E SER -22 ? E SER 3   
532 1 Y 1 E GLY -21 ? E GLY 4   
533 1 Y 1 E LEU -20 ? E LEU 5   
534 1 Y 1 E LEU -19 ? E LEU 6   
535 1 Y 1 E GLU -18 ? E GLU 7   
536 1 Y 1 E LEU -17 ? E LEU 8   
537 1 Y 1 E LEU -16 ? E LEU 9   
538 1 Y 1 E LEU -15 ? E LEU 10  
539 1 Y 1 E PRO -14 ? E PRO 11  
540 1 Y 1 E ILE -13 ? E ILE 12  
541 1 Y 1 E TRP -12 ? E TRP 13  
542 1 Y 1 E LEU -11 ? E LEU 14  
543 1 Y 1 E SER -10 ? E SER 15  
544 1 Y 1 E TRP -9  ? E TRP 16  
545 1 Y 1 E THR -8  ? E THR 17  
546 1 Y 1 E LEU -7  ? E LEU 18  
547 1 Y 1 E GLY -6  ? E GLY 19  
548 1 Y 1 E THR -5  ? E THR 20  
549 1 Y 1 E ARG -4  ? E ARG 21  
550 1 Y 1 E GLY -3  ? E GLY 22  
551 1 Y 1 E SER -2  ? E SER 23  
552 1 Y 1 E GLU -1  ? E GLU 24  
553 1 Y 1 E PRO 0   ? E PRO 25  
554 1 Y 1 E ARG 1   ? E ARG 26  
555 1 Y 1 E SER 2   ? E SER 27  
556 1 Y 1 E VAL 3   ? E VAL 28  
557 1 Y 1 E ASN 4   ? E ASN 29  
558 1 Y 1 E ASP 5   ? E ASP 30  
559 1 Y 1 E PRO 6   ? E PRO 31  
560 1 Y 1 E GLY 7   ? E GLY 32  
561 1 Y 1 E ASN 8   ? E ASN 33  
562 1 Y 1 E GLY 335 ? E GLY 335 
563 1 Y 1 E PRO 336 ? E PRO 336 
564 1 Y 1 E GLN 337 ? E GLN 337 
565 1 Y 1 E ARG 338 ? E ARG 338 
566 1 Y 1 E GLN 339 ? E GLN 339 
567 1 Y 1 E LYS 340 ? E LYS 340 
568 1 Y 1 E LYS 341 ? E LYS 341 
569 1 Y 1 E LEU 342 ? E LEU 342 
570 1 Y 1 E ALA 343 ? E ALA 343 
571 1 Y 1 E GLU 344 ? E GLU 344 
572 1 Y 1 E LYS 345 ? E LYS 345 
573 1 Y 1 E THR 346 ? E THR 346 
574 1 Y 1 E ALA 347 ? E ALA 347 
575 1 Y 1 E LYS 348 ? E LYS 348 
576 1 Y 1 E ALA 349 ? E ALA 349 
577 1 Y 1 E LYS 350 ? E LYS 350 
578 1 Y 1 E ASN 351 ? E ASN 351 
579 1 Y 1 E ASP 352 ? E ASP 352 
580 1 Y 1 E ARG 353 ? E ARG 353 
581 1 Y 1 E SER 354 ? E SER 354 
582 1 Y 1 E LYS 355 ? E LYS 355 
583 1 Y 1 E SER 356 ? E SER 356 
584 1 Y 1 E GLU 357 ? E GLU 357 
585 1 Y 1 E SER 358 ? E SER 358 
586 1 Y 1 E ASN 359 ? E ASN 359 
587 1 Y 1 E ARG 360 ? E ARG 360 
588 1 Y 1 E VAL 361 ? E VAL 361 
589 1 Y 1 E ASP 362 ? E ASP 362 
590 1 Y 1 E ALA 363 ? E ALA 363 
591 1 Y 1 E HIS 364 ? E HIS 364 
592 1 Y 1 E GLY 365 ? E GLY 365 
593 1 Y 1 E ASN 366 ? E ASN 366 
594 1 Y 1 E ILE 367 ? E ILE 367 
595 1 Y 1 E LEU 368 ? E LEU 368 
596 1 Y 1 E LEU 369 ? E LEU 369 
597 1 Y 1 E THR 370 ? E THR 370 
598 1 Y 1 E SER 371 ? E SER 371 
599 1 Y 1 E LEU 372 ? E LEU 372 
600 1 Y 1 E GLU 373 ? E GLU 373 
601 1 Y 1 E VAL 374 ? E VAL 374 
602 1 Y 1 E HIS 375 ? E HIS 375 
603 1 Y 1 E ASN 376 ? E ASN 376 
604 1 Y 1 E GLU 377 ? E GLU 377 
605 1 Y 1 E MET 378 ? E MET 378 
606 1 Y 1 E ASN 379 ? E ASN 379 
607 1 Y 1 E GLU 380 ? E GLU 380 
608 1 Y 1 E VAL 381 ? E VAL 381 
609 1 Y 1 E SER 382 ? E SER 382 
610 1 Y 1 E GLY 383 ? E GLY 383 
611 1 Y 1 E GLY 384 ? E GLY 384 
612 1 Y 1 E ILE 385 ? E ILE 385 
613 1 Y 1 E GLY 386 ? E GLY 386 
614 1 Y 1 E ASP 387 ? E ASP 387 
615 1 Y 1 E THR 388 ? E THR 388 
616 1 Y 1 E ARG 389 ? E ARG 389 
617 1 Y 1 E ASN 390 ? E ASN 390 
618 1 Y 1 E SER 391 ? E SER 391 
619 1 Y 1 E ALA 392 ? E ALA 392 
620 1 Y 1 E ILE 393 ? E ILE 393 
621 1 Y 1 E SER 394 ? E SER 394 
622 1 Y 1 E PHE 395 ? E PHE 395 
623 1 Y 1 E ASP 396 ? E ASP 396 
624 1 Y 1 E ASN 397 ? E ASN 397 
625 1 Y 1 E SER 398 ? E SER 398 
626 1 Y 1 E GLY 399 ? E GLY 399 
627 1 Y 1 E ILE 400 ? E ILE 400 
628 1 Y 1 E GLN 401 ? E GLN 401 
629 1 Y 1 E TYR 402 ? E TYR 402 
630 1 Y 1 E ARG 403 ? E ARG 403 
631 1 Y 1 E LYS 404 ? E LYS 404 
632 1 Y 1 E GLN 405 ? E GLN 405 
633 1 Y 1 E SER 406 ? E SER 406 
634 1 Y 1 E MET 407 ? E MET 407 
635 1 Y 1 E PRO 408 ? E PRO 408 
636 1 Y 1 E ARG 409 ? E ARG 409 
637 1 Y 1 E GLU 410 ? E GLU 410 
638 1 Y 1 E GLY 411 ? E GLY 411 
639 1 Y 1 E HIS 412 ? E HIS 412 
640 1 Y 1 E GLY 413 ? E GLY 413 
641 1 Y 1 E ARG 414 ? E ARG 414 
642 1 Y 1 E PHE 415 ? E PHE 415 
643 1 Y 1 E LEU 416 ? E LEU 416 
644 1 Y 1 E GLY 417 ? E GLY 417 
645 1 Y 1 E ASP 418 ? E ASP 418 
646 1 Y 1 E ARG 419 ? E ARG 419 
647 1 Y 1 E SER 420 ? E SER 420 
648 1 Y 1 E LEU 421 ? E LEU 421 
649 1 Y 1 E PRO 422 ? E PRO 422 
650 1 Y 1 E HIS 423 ? E HIS 423 
651 1 Y 1 E LYS 424 ? E LYS 424 
652 1 Y 1 E LYS 425 ? E LYS 425 
653 1 Y 1 E THR 426 ? E THR 426 
654 1 Y 1 E HIS 427 ? E HIS 427 
655 1 Y 1 E LEU 428 ? E LEU 428 
656 1 Y 1 E ARG 429 ? E ARG 429 
657 1 Y 1 E ARG 430 ? E ARG 430 
658 1 Y 1 E ARG 431 ? E ARG 431 
659 1 Y 1 E SER 432 ? E SER 432 
660 1 Y 1 E SER 433 ? E SER 433 
661 1 Y 1 E GLN 434 ? E GLN 434 
662 1 Y 1 E LEU 435 ? E LEU 435 
663 1 Y 1 E LYS 436 ? E LYS 436 
664 1 Y 1 E ILE 437 ? E ILE 437 
665 1 Y 1 E LYS 438 ? E LYS 438 
666 1 Y 1 E ILE 439 ? E ILE 439 
667 1 Y 1 E PRO 440 ? E PRO 440 
668 1 Y 1 E ASP 441 ? E ASP 441 
669 1 Y 1 E LEU 442 ? E LEU 442 
670 1 Y 1 E THR 443 ? E THR 443 
671 1 Y 1 E ASN 473 ? E ASN 473 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GLN N    N N N 112 
GLN CA   C N S 113 
GLN C    C N N 114 
GLN O    O N N 115 
GLN CB   C N N 116 
GLN CG   C N N 117 
GLN CD   C N N 118 
GLN OE1  O N N 119 
GLN NE2  N N N 120 
GLN OXT  O N N 121 
GLN H    H N N 122 
GLN H2   H N N 123 
GLN HA   H N N 124 
GLN HB2  H N N 125 
GLN HB3  H N N 126 
GLN HG2  H N N 127 
GLN HG3  H N N 128 
GLN HE21 H N N 129 
GLN HE22 H N N 130 
GLN HXT  H N N 131 
GLU N    N N N 132 
GLU CA   C N S 133 
GLU C    C N N 134 
GLU O    O N N 135 
GLU CB   C N N 136 
GLU CG   C N N 137 
GLU CD   C N N 138 
GLU OE1  O N N 139 
GLU OE2  O N N 140 
GLU OXT  O N N 141 
GLU H    H N N 142 
GLU H2   H N N 143 
GLU HA   H N N 144 
GLU HB2  H N N 145 
GLU HB3  H N N 146 
GLU HG2  H N N 147 
GLU HG3  H N N 148 
GLU HE2  H N N 149 
GLU HXT  H N N 150 
GLY N    N N N 151 
GLY CA   C N N 152 
GLY C    C N N 153 
GLY O    O N N 154 
GLY OXT  O N N 155 
GLY H    H N N 156 
GLY H2   H N N 157 
GLY HA2  H N N 158 
GLY HA3  H N N 159 
GLY HXT  H N N 160 
HIS N    N N N 161 
HIS CA   C N S 162 
HIS C    C N N 163 
HIS O    O N N 164 
HIS CB   C N N 165 
HIS CG   C Y N 166 
HIS ND1  N Y N 167 
HIS CD2  C Y N 168 
HIS CE1  C Y N 169 
HIS NE2  N Y N 170 
HIS OXT  O N N 171 
HIS H    H N N 172 
HIS H2   H N N 173 
HIS HA   H N N 174 
HIS HB2  H N N 175 
HIS HB3  H N N 176 
HIS HD1  H N N 177 
HIS HD2  H N N 178 
HIS HE1  H N N 179 
HIS HE2  H N N 180 
HIS HXT  H N N 181 
ILE N    N N N 182 
ILE CA   C N S 183 
ILE C    C N N 184 
ILE O    O N N 185 
ILE CB   C N S 186 
ILE CG1  C N N 187 
ILE CG2  C N N 188 
ILE CD1  C N N 189 
ILE OXT  O N N 190 
ILE H    H N N 191 
ILE H2   H N N 192 
ILE HA   H N N 193 
ILE HB   H N N 194 
ILE HG12 H N N 195 
ILE HG13 H N N 196 
ILE HG21 H N N 197 
ILE HG22 H N N 198 
ILE HG23 H N N 199 
ILE HD11 H N N 200 
ILE HD12 H N N 201 
ILE HD13 H N N 202 
ILE HXT  H N N 203 
LEU N    N N N 204 
LEU CA   C N S 205 
LEU C    C N N 206 
LEU O    O N N 207 
LEU CB   C N N 208 
LEU CG   C N N 209 
LEU CD1  C N N 210 
LEU CD2  C N N 211 
LEU OXT  O N N 212 
LEU H    H N N 213 
LEU H2   H N N 214 
LEU HA   H N N 215 
LEU HB2  H N N 216 
LEU HB3  H N N 217 
LEU HG   H N N 218 
LEU HD11 H N N 219 
LEU HD12 H N N 220 
LEU HD13 H N N 221 
LEU HD21 H N N 222 
LEU HD22 H N N 223 
LEU HD23 H N N 224 
LEU HXT  H N N 225 
LYS N    N N N 226 
LYS CA   C N S 227 
LYS C    C N N 228 
LYS O    O N N 229 
LYS CB   C N N 230 
LYS CG   C N N 231 
LYS CD   C N N 232 
LYS CE   C N N 233 
LYS NZ   N N N 234 
LYS OXT  O N N 235 
LYS H    H N N 236 
LYS H2   H N N 237 
LYS HA   H N N 238 
LYS HB2  H N N 239 
LYS HB3  H N N 240 
LYS HG2  H N N 241 
LYS HG3  H N N 242 
LYS HD2  H N N 243 
LYS HD3  H N N 244 
LYS HE2  H N N 245 
LYS HE3  H N N 246 
LYS HZ1  H N N 247 
LYS HZ2  H N N 248 
LYS HZ3  H N N 249 
LYS HXT  H N N 250 
MAN C1   C N S 251 
MAN C2   C N S 252 
MAN C3   C N S 253 
MAN C4   C N S 254 
MAN C5   C N R 255 
MAN C6   C N N 256 
MAN O1   O N N 257 
MAN O2   O N N 258 
MAN O3   O N N 259 
MAN O4   O N N 260 
MAN O5   O N N 261 
MAN O6   O N N 262 
MAN H1   H N N 263 
MAN H2   H N N 264 
MAN H3   H N N 265 
MAN H4   H N N 266 
MAN H5   H N N 267 
MAN H61  H N N 268 
MAN H62  H N N 269 
MAN HO1  H N N 270 
MAN HO2  H N N 271 
MAN HO3  H N N 272 
MAN HO4  H N N 273 
MAN HO6  H N N 274 
MET N    N N N 275 
MET CA   C N S 276 
MET C    C N N 277 
MET O    O N N 278 
MET CB   C N N 279 
MET CG   C N N 280 
MET SD   S N N 281 
MET CE   C N N 282 
MET OXT  O N N 283 
MET H    H N N 284 
MET H2   H N N 285 
MET HA   H N N 286 
MET HB2  H N N 287 
MET HB3  H N N 288 
MET HG2  H N N 289 
MET HG3  H N N 290 
MET HE1  H N N 291 
MET HE2  H N N 292 
MET HE3  H N N 293 
MET HXT  H N N 294 
NAG C1   C N R 295 
NAG C2   C N R 296 
NAG C3   C N R 297 
NAG C4   C N S 298 
NAG C5   C N R 299 
NAG C6   C N N 300 
NAG C7   C N N 301 
NAG C8   C N N 302 
NAG N2   N N N 303 
NAG O1   O N N 304 
NAG O3   O N N 305 
NAG O4   O N N 306 
NAG O5   O N N 307 
NAG O6   O N N 308 
NAG O7   O N N 309 
NAG H1   H N N 310 
NAG H2   H N N 311 
NAG H3   H N N 312 
NAG H4   H N N 313 
NAG H5   H N N 314 
NAG H61  H N N 315 
NAG H62  H N N 316 
NAG H81  H N N 317 
NAG H82  H N N 318 
NAG H83  H N N 319 
NAG HN2  H N N 320 
NAG HO1  H N N 321 
NAG HO3  H N N 322 
NAG HO4  H N N 323 
NAG HO6  H N N 324 
PHE N    N N N 325 
PHE CA   C N S 326 
PHE C    C N N 327 
PHE O    O N N 328 
PHE CB   C N N 329 
PHE CG   C Y N 330 
PHE CD1  C Y N 331 
PHE CD2  C Y N 332 
PHE CE1  C Y N 333 
PHE CE2  C Y N 334 
PHE CZ   C Y N 335 
PHE OXT  O N N 336 
PHE H    H N N 337 
PHE H2   H N N 338 
PHE HA   H N N 339 
PHE HB2  H N N 340 
PHE HB3  H N N 341 
PHE HD1  H N N 342 
PHE HD2  H N N 343 
PHE HE1  H N N 344 
PHE HE2  H N N 345 
PHE HZ   H N N 346 
PHE HXT  H N N 347 
PIO C1   C N R 348 
PIO O1   O N N 349 
PIO P1   P N N 350 
PIO C2   C N R 351 
PIO O2   O N N 352 
PIO C3   C N S 353 
PIO O3   O N N 354 
PIO C4   C N R 355 
PIO O4   O N N 356 
PIO P4   P N N 357 
PIO C5   C N R 358 
PIO O5   O N N 359 
PIO P5   P N N 360 
PIO C6   C N S 361 
PIO O6   O N N 362 
PIO O11  O N N 363 
PIO O12  O N N 364 
PIO O13  O N N 365 
PIO C1A  C N N 366 
PIO O1A  O N N 367 
PIO C1B  C N N 368 
PIO O1B  O N N 369 
PIO C1C  C N N 370 
PIO C2A  C N N 371 
PIO C2B  C N N 372 
PIO C2C  C N R 373 
PIO O2C  O N N 374 
PIO C3A  C N N 375 
PIO C3B  C N N 376 
PIO C3C  C N N 377 
PIO O3C  O N N 378 
PIO O41  O N N 379 
PIO O42  O N N 380 
PIO O43  O N N 381 
PIO C4A  C N N 382 
PIO C4B  C N N 383 
PIO O51  O N N 384 
PIO O52  O N N 385 
PIO O53  O N N 386 
PIO C5A  C N N 387 
PIO C5B  C N N 388 
PIO C6A  C N N 389 
PIO C6B  C N N 390 
PIO C7A  C N N 391 
PIO C7B  C N N 392 
PIO C8A  C N N 393 
PIO C8B  C N N 394 
PIO H1   H N N 395 
PIO H2   H N N 396 
PIO H3   H N N 397 
PIO H4   H N N 398 
PIO H5   H N N 399 
PIO H6   H N N 400 
PIO H1C  H N N 401 
PIO H1CA H N N 402 
PIO H3C  H N N 403 
PIO H3CA H N N 404 
PIO H2A  H N N 405 
PIO H3A  H N N 406 
PIO H4A  H N N 407 
PIO H5A  H N N 408 
PIO H6A  H N N 409 
PIO H7A  H N N 410 
PIO H8A  H N N 411 
PIO H2AA H N N 412 
PIO H3AA H N N 413 
PIO H4AA H N N 414 
PIO H5AA H N N 415 
PIO H6AA H N N 416 
PIO H7AA H N N 417 
PIO H8AA H N N 418 
PIO H8AB H N N 419 
PIO H2B  H N N 420 
PIO H3B  H N N 421 
PIO H4B  H N N 422 
PIO H5B  H N N 423 
PIO H6B  H N N 424 
PIO H7B  H N N 425 
PIO H8B  H N N 426 
PIO H2BA H N N 427 
PIO H3BA H N N 428 
PIO H4BA H N N 429 
PIO H5BA H N N 430 
PIO H6BA H N N 431 
PIO H7BA H N N 432 
PIO H8BA H N N 433 
PIO H8BB H N N 434 
PIO H2C  H N N 435 
PIO HO2  H N N 436 
PIO HO3  H N N 437 
PIO HO6  H N N 438 
PIO H41  H N N 439 
PIO H43  H N N 440 
PIO H51  H N N 441 
PIO H52  H N N 442 
PIO H11  H N N 443 
PRO N    N N N 444 
PRO CA   C N S 445 
PRO C    C N N 446 
PRO O    O N N 447 
PRO CB   C N N 448 
PRO CG   C N N 449 
PRO CD   C N N 450 
PRO OXT  O N N 451 
PRO H    H N N 452 
PRO HA   H N N 453 
PRO HB2  H N N 454 
PRO HB3  H N N 455 
PRO HG2  H N N 456 
PRO HG3  H N N 457 
PRO HD2  H N N 458 
PRO HD3  H N N 459 
PRO HXT  H N N 460 
SER N    N N N 461 
SER CA   C N S 462 
SER C    C N N 463 
SER O    O N N 464 
SER CB   C N N 465 
SER OG   O N N 466 
SER OXT  O N N 467 
SER H    H N N 468 
SER H2   H N N 469 
SER HA   H N N 470 
SER HB2  H N N 471 
SER HB3  H N N 472 
SER HG   H N N 473 
SER HXT  H N N 474 
THR N    N N N 475 
THR CA   C N S 476 
THR C    C N N 477 
THR O    O N N 478 
THR CB   C N R 479 
THR OG1  O N N 480 
THR CG2  C N N 481 
THR OXT  O N N 482 
THR H    H N N 483 
THR H2   H N N 484 
THR HA   H N N 485 
THR HB   H N N 486 
THR HG1  H N N 487 
THR HG21 H N N 488 
THR HG22 H N N 489 
THR HG23 H N N 490 
THR HXT  H N N 491 
TRP N    N N N 492 
TRP CA   C N S 493 
TRP C    C N N 494 
TRP O    O N N 495 
TRP CB   C N N 496 
TRP CG   C Y N 497 
TRP CD1  C Y N 498 
TRP CD2  C Y N 499 
TRP NE1  N Y N 500 
TRP CE2  C Y N 501 
TRP CE3  C Y N 502 
TRP CZ2  C Y N 503 
TRP CZ3  C Y N 504 
TRP CH2  C Y N 505 
TRP OXT  O N N 506 
TRP H    H N N 507 
TRP H2   H N N 508 
TRP HA   H N N 509 
TRP HB2  H N N 510 
TRP HB3  H N N 511 
TRP HD1  H N N 512 
TRP HE1  H N N 513 
TRP HE3  H N N 514 
TRP HZ2  H N N 515 
TRP HZ3  H N N 516 
TRP HH2  H N N 517 
TRP HXT  H N N 518 
TYR N    N N N 519 
TYR CA   C N S 520 
TYR C    C N N 521 
TYR O    O N N 522 
TYR CB   C N N 523 
TYR CG   C Y N 524 
TYR CD1  C Y N 525 
TYR CD2  C Y N 526 
TYR CE1  C Y N 527 
TYR CE2  C Y N 528 
TYR CZ   C Y N 529 
TYR OH   O N N 530 
TYR OXT  O N N 531 
TYR H    H N N 532 
TYR H2   H N N 533 
TYR HA   H N N 534 
TYR HB2  H N N 535 
TYR HB3  H N N 536 
TYR HD1  H N N 537 
TYR HD2  H N N 538 
TYR HE1  H N N 539 
TYR HE2  H N N 540 
TYR HH   H N N 541 
TYR HXT  H N N 542 
VAL N    N N N 543 
VAL CA   C N S 544 
VAL C    C N N 545 
VAL O    O N N 546 
VAL CB   C N N 547 
VAL CG1  C N N 548 
VAL CG2  C N N 549 
VAL OXT  O N N 550 
VAL H    H N N 551 
VAL H2   H N N 552 
VAL HA   H N N 553 
VAL HB   H N N 554 
VAL HG11 H N N 555 
VAL HG12 H N N 556 
VAL HG13 H N N 557 
VAL HG21 H N N 558 
VAL HG22 H N N 559 
VAL HG23 H N N 560 
VAL HXT  H N N 561 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GLN N   CA   sing N N 107 
GLN N   H    sing N N 108 
GLN N   H2   sing N N 109 
GLN CA  C    sing N N 110 
GLN CA  CB   sing N N 111 
GLN CA  HA   sing N N 112 
GLN C   O    doub N N 113 
GLN C   OXT  sing N N 114 
GLN CB  CG   sing N N 115 
GLN CB  HB2  sing N N 116 
GLN CB  HB3  sing N N 117 
GLN CG  CD   sing N N 118 
GLN CG  HG2  sing N N 119 
GLN CG  HG3  sing N N 120 
GLN CD  OE1  doub N N 121 
GLN CD  NE2  sing N N 122 
GLN NE2 HE21 sing N N 123 
GLN NE2 HE22 sing N N 124 
GLN OXT HXT  sing N N 125 
GLU N   CA   sing N N 126 
GLU N   H    sing N N 127 
GLU N   H2   sing N N 128 
GLU CA  C    sing N N 129 
GLU CA  CB   sing N N 130 
GLU CA  HA   sing N N 131 
GLU C   O    doub N N 132 
GLU C   OXT  sing N N 133 
GLU CB  CG   sing N N 134 
GLU CB  HB2  sing N N 135 
GLU CB  HB3  sing N N 136 
GLU CG  CD   sing N N 137 
GLU CG  HG2  sing N N 138 
GLU CG  HG3  sing N N 139 
GLU CD  OE1  doub N N 140 
GLU CD  OE2  sing N N 141 
GLU OE2 HE2  sing N N 142 
GLU OXT HXT  sing N N 143 
GLY N   CA   sing N N 144 
GLY N   H    sing N N 145 
GLY N   H2   sing N N 146 
GLY CA  C    sing N N 147 
GLY CA  HA2  sing N N 148 
GLY CA  HA3  sing N N 149 
GLY C   O    doub N N 150 
GLY C   OXT  sing N N 151 
GLY OXT HXT  sing N N 152 
HIS N   CA   sing N N 153 
HIS N   H    sing N N 154 
HIS N   H2   sing N N 155 
HIS CA  C    sing N N 156 
HIS CA  CB   sing N N 157 
HIS CA  HA   sing N N 158 
HIS C   O    doub N N 159 
HIS C   OXT  sing N N 160 
HIS CB  CG   sing N N 161 
HIS CB  HB2  sing N N 162 
HIS CB  HB3  sing N N 163 
HIS CG  ND1  sing Y N 164 
HIS CG  CD2  doub Y N 165 
HIS ND1 CE1  doub Y N 166 
HIS ND1 HD1  sing N N 167 
HIS CD2 NE2  sing Y N 168 
HIS CD2 HD2  sing N N 169 
HIS CE1 NE2  sing Y N 170 
HIS CE1 HE1  sing N N 171 
HIS NE2 HE2  sing N N 172 
HIS OXT HXT  sing N N 173 
ILE N   CA   sing N N 174 
ILE N   H    sing N N 175 
ILE N   H2   sing N N 176 
ILE CA  C    sing N N 177 
ILE CA  CB   sing N N 178 
ILE CA  HA   sing N N 179 
ILE C   O    doub N N 180 
ILE C   OXT  sing N N 181 
ILE CB  CG1  sing N N 182 
ILE CB  CG2  sing N N 183 
ILE CB  HB   sing N N 184 
ILE CG1 CD1  sing N N 185 
ILE CG1 HG12 sing N N 186 
ILE CG1 HG13 sing N N 187 
ILE CG2 HG21 sing N N 188 
ILE CG2 HG22 sing N N 189 
ILE CG2 HG23 sing N N 190 
ILE CD1 HD11 sing N N 191 
ILE CD1 HD12 sing N N 192 
ILE CD1 HD13 sing N N 193 
ILE OXT HXT  sing N N 194 
LEU N   CA   sing N N 195 
LEU N   H    sing N N 196 
LEU N   H2   sing N N 197 
LEU CA  C    sing N N 198 
LEU CA  CB   sing N N 199 
LEU CA  HA   sing N N 200 
LEU C   O    doub N N 201 
LEU C   OXT  sing N N 202 
LEU CB  CG   sing N N 203 
LEU CB  HB2  sing N N 204 
LEU CB  HB3  sing N N 205 
LEU CG  CD1  sing N N 206 
LEU CG  CD2  sing N N 207 
LEU CG  HG   sing N N 208 
LEU CD1 HD11 sing N N 209 
LEU CD1 HD12 sing N N 210 
LEU CD1 HD13 sing N N 211 
LEU CD2 HD21 sing N N 212 
LEU CD2 HD22 sing N N 213 
LEU CD2 HD23 sing N N 214 
LEU OXT HXT  sing N N 215 
LYS N   CA   sing N N 216 
LYS N   H    sing N N 217 
LYS N   H2   sing N N 218 
LYS CA  C    sing N N 219 
LYS CA  CB   sing N N 220 
LYS CA  HA   sing N N 221 
LYS C   O    doub N N 222 
LYS C   OXT  sing N N 223 
LYS CB  CG   sing N N 224 
LYS CB  HB2  sing N N 225 
LYS CB  HB3  sing N N 226 
LYS CG  CD   sing N N 227 
LYS CG  HG2  sing N N 228 
LYS CG  HG3  sing N N 229 
LYS CD  CE   sing N N 230 
LYS CD  HD2  sing N N 231 
LYS CD  HD3  sing N N 232 
LYS CE  NZ   sing N N 233 
LYS CE  HE2  sing N N 234 
LYS CE  HE3  sing N N 235 
LYS NZ  HZ1  sing N N 236 
LYS NZ  HZ2  sing N N 237 
LYS NZ  HZ3  sing N N 238 
LYS OXT HXT  sing N N 239 
MAN C1  C2   sing N N 240 
MAN C1  O1   sing N N 241 
MAN C1  O5   sing N N 242 
MAN C1  H1   sing N N 243 
MAN C2  C3   sing N N 244 
MAN C2  O2   sing N N 245 
MAN C2  H2   sing N N 246 
MAN C3  C4   sing N N 247 
MAN C3  O3   sing N N 248 
MAN C3  H3   sing N N 249 
MAN C4  C5   sing N N 250 
MAN C4  O4   sing N N 251 
MAN C4  H4   sing N N 252 
MAN C5  C6   sing N N 253 
MAN C5  O5   sing N N 254 
MAN C5  H5   sing N N 255 
MAN C6  O6   sing N N 256 
MAN C6  H61  sing N N 257 
MAN C6  H62  sing N N 258 
MAN O1  HO1  sing N N 259 
MAN O2  HO2  sing N N 260 
MAN O3  HO3  sing N N 261 
MAN O4  HO4  sing N N 262 
MAN O6  HO6  sing N N 263 
MET N   CA   sing N N 264 
MET N   H    sing N N 265 
MET N   H2   sing N N 266 
MET CA  C    sing N N 267 
MET CA  CB   sing N N 268 
MET CA  HA   sing N N 269 
MET C   O    doub N N 270 
MET C   OXT  sing N N 271 
MET CB  CG   sing N N 272 
MET CB  HB2  sing N N 273 
MET CB  HB3  sing N N 274 
MET CG  SD   sing N N 275 
MET CG  HG2  sing N N 276 
MET CG  HG3  sing N N 277 
MET SD  CE   sing N N 278 
MET CE  HE1  sing N N 279 
MET CE  HE2  sing N N 280 
MET CE  HE3  sing N N 281 
MET OXT HXT  sing N N 282 
NAG C1  C2   sing N N 283 
NAG C1  O1   sing N N 284 
NAG C1  O5   sing N N 285 
NAG C1  H1   sing N N 286 
NAG C2  C3   sing N N 287 
NAG C2  N2   sing N N 288 
NAG C2  H2   sing N N 289 
NAG C3  C4   sing N N 290 
NAG C3  O3   sing N N 291 
NAG C3  H3   sing N N 292 
NAG C4  C5   sing N N 293 
NAG C4  O4   sing N N 294 
NAG C4  H4   sing N N 295 
NAG C5  C6   sing N N 296 
NAG C5  O5   sing N N 297 
NAG C5  H5   sing N N 298 
NAG C6  O6   sing N N 299 
NAG C6  H61  sing N N 300 
NAG C6  H62  sing N N 301 
NAG C7  C8   sing N N 302 
NAG C7  N2   sing N N 303 
NAG C7  O7   doub N N 304 
NAG C8  H81  sing N N 305 
NAG C8  H82  sing N N 306 
NAG C8  H83  sing N N 307 
NAG N2  HN2  sing N N 308 
NAG O1  HO1  sing N N 309 
NAG O3  HO3  sing N N 310 
NAG O4  HO4  sing N N 311 
NAG O6  HO6  sing N N 312 
PHE N   CA   sing N N 313 
PHE N   H    sing N N 314 
PHE N   H2   sing N N 315 
PHE CA  C    sing N N 316 
PHE CA  CB   sing N N 317 
PHE CA  HA   sing N N 318 
PHE C   O    doub N N 319 
PHE C   OXT  sing N N 320 
PHE CB  CG   sing N N 321 
PHE CB  HB2  sing N N 322 
PHE CB  HB3  sing N N 323 
PHE CG  CD1  doub Y N 324 
PHE CG  CD2  sing Y N 325 
PHE CD1 CE1  sing Y N 326 
PHE CD1 HD1  sing N N 327 
PHE CD2 CE2  doub Y N 328 
PHE CD2 HD2  sing N N 329 
PHE CE1 CZ   doub Y N 330 
PHE CE1 HE1  sing N N 331 
PHE CE2 CZ   sing Y N 332 
PHE CE2 HE2  sing N N 333 
PHE CZ  HZ   sing N N 334 
PHE OXT HXT  sing N N 335 
PIO C1  O1   sing N N 336 
PIO C1  C2   sing N N 337 
PIO C1  C6   sing N N 338 
PIO C1  H1   sing N N 339 
PIO O1  P1   sing N N 340 
PIO P1  O11  sing N N 341 
PIO O11 H11  sing N N 342 
PIO P1  O12  doub N N 343 
PIO P1  O13  sing N N 344 
PIO C2  O2   sing N N 345 
PIO C2  C3   sing N N 346 
PIO C2  H2   sing N N 347 
PIO O2  HO2  sing N N 348 
PIO C3  O3   sing N N 349 
PIO C3  C4   sing N N 350 
PIO C3  H3   sing N N 351 
PIO O3  HO3  sing N N 352 
PIO C4  O4   sing N N 353 
PIO C4  C5   sing N N 354 
PIO C4  H4   sing N N 355 
PIO O4  P4   sing N N 356 
PIO P4  O41  sing N N 357 
PIO O41 H41  sing N N 358 
PIO P4  O42  doub N N 359 
PIO P4  O43  sing N N 360 
PIO O43 H43  sing N N 361 
PIO C5  O5   sing N N 362 
PIO C5  C6   sing N N 363 
PIO C5  H5   sing N N 364 
PIO O5  P5   sing N N 365 
PIO P5  O51  sing N N 366 
PIO O51 H51  sing N N 367 
PIO P5  O52  sing N N 368 
PIO O52 H52  sing N N 369 
PIO P5  O53  doub N N 370 
PIO C6  O6   sing N N 371 
PIO C6  H6   sing N N 372 
PIO O6  HO6  sing N N 373 
PIO O13 C1C  sing N N 374 
PIO C1A O1A  doub N N 375 
PIO C1A C2A  sing N N 376 
PIO C1A O2C  sing N N 377 
PIO C1B O1B  doub N N 378 
PIO C1B C2B  sing N N 379 
PIO C1B O3C  sing N N 380 
PIO C1C C2C  sing N N 381 
PIO C1C H1C  sing N N 382 
PIO C1C H1CA sing N N 383 
PIO C2A C3A  sing N N 384 
PIO C2A H2A  sing N N 385 
PIO C2A H2AA sing N N 386 
PIO C2B C3B  sing N N 387 
PIO C2B H2B  sing N N 388 
PIO C2B H2BA sing N N 389 
PIO C2C O2C  sing N N 390 
PIO C2C C3C  sing N N 391 
PIO C2C H2C  sing N N 392 
PIO C3A C4A  sing N N 393 
PIO C3A H3A  sing N N 394 
PIO C3A H3AA sing N N 395 
PIO C3B C4B  sing N N 396 
PIO C3B H3B  sing N N 397 
PIO C3B H3BA sing N N 398 
PIO C3C O3C  sing N N 399 
PIO C3C H3C  sing N N 400 
PIO C3C H3CA sing N N 401 
PIO C4A C5A  sing N N 402 
PIO C4A H4A  sing N N 403 
PIO C4A H4AA sing N N 404 
PIO C4B C5B  sing N N 405 
PIO C4B H4B  sing N N 406 
PIO C4B H4BA sing N N 407 
PIO C5A C6A  sing N N 408 
PIO C5A H5A  sing N N 409 
PIO C5A H5AA sing N N 410 
PIO C5B C6B  sing N N 411 
PIO C5B H5B  sing N N 412 
PIO C5B H5BA sing N N 413 
PIO C6A C7A  sing N N 414 
PIO C6A H6A  sing N N 415 
PIO C6A H6AA sing N N 416 
PIO C6B C7B  sing N N 417 
PIO C6B H6B  sing N N 418 
PIO C6B H6BA sing N N 419 
PIO C7A C8A  sing N N 420 
PIO C7A H7A  sing N N 421 
PIO C7A H7AA sing N N 422 
PIO C7B C8B  sing N N 423 
PIO C7B H7B  sing N N 424 
PIO C7B H7BA sing N N 425 
PIO C8A H8A  sing N N 426 
PIO C8A H8AA sing N N 427 
PIO C8A H8AB sing N N 428 
PIO C8B H8B  sing N N 429 
PIO C8B H8BA sing N N 430 
PIO C8B H8BB sing N N 431 
PRO N   CA   sing N N 432 
PRO N   CD   sing N N 433 
PRO N   H    sing N N 434 
PRO CA  C    sing N N 435 
PRO CA  CB   sing N N 436 
PRO CA  HA   sing N N 437 
PRO C   O    doub N N 438 
PRO C   OXT  sing N N 439 
PRO CB  CG   sing N N 440 
PRO CB  HB2  sing N N 441 
PRO CB  HB3  sing N N 442 
PRO CG  CD   sing N N 443 
PRO CG  HG2  sing N N 444 
PRO CG  HG3  sing N N 445 
PRO CD  HD2  sing N N 446 
PRO CD  HD3  sing N N 447 
PRO OXT HXT  sing N N 448 
SER N   CA   sing N N 449 
SER N   H    sing N N 450 
SER N   H2   sing N N 451 
SER CA  C    sing N N 452 
SER CA  CB   sing N N 453 
SER CA  HA   sing N N 454 
SER C   O    doub N N 455 
SER C   OXT  sing N N 456 
SER CB  OG   sing N N 457 
SER CB  HB2  sing N N 458 
SER CB  HB3  sing N N 459 
SER OG  HG   sing N N 460 
SER OXT HXT  sing N N 461 
THR N   CA   sing N N 462 
THR N   H    sing N N 463 
THR N   H2   sing N N 464 
THR CA  C    sing N N 465 
THR CA  CB   sing N N 466 
THR CA  HA   sing N N 467 
THR C   O    doub N N 468 
THR C   OXT  sing N N 469 
THR CB  OG1  sing N N 470 
THR CB  CG2  sing N N 471 
THR CB  HB   sing N N 472 
THR OG1 HG1  sing N N 473 
THR CG2 HG21 sing N N 474 
THR CG2 HG22 sing N N 475 
THR CG2 HG23 sing N N 476 
THR OXT HXT  sing N N 477 
TRP N   CA   sing N N 478 
TRP N   H    sing N N 479 
TRP N   H2   sing N N 480 
TRP CA  C    sing N N 481 
TRP CA  CB   sing N N 482 
TRP CA  HA   sing N N 483 
TRP C   O    doub N N 484 
TRP C   OXT  sing N N 485 
TRP CB  CG   sing N N 486 
TRP CB  HB2  sing N N 487 
TRP CB  HB3  sing N N 488 
TRP CG  CD1  doub Y N 489 
TRP CG  CD2  sing Y N 490 
TRP CD1 NE1  sing Y N 491 
TRP CD1 HD1  sing N N 492 
TRP CD2 CE2  doub Y N 493 
TRP CD2 CE3  sing Y N 494 
TRP NE1 CE2  sing Y N 495 
TRP NE1 HE1  sing N N 496 
TRP CE2 CZ2  sing Y N 497 
TRP CE3 CZ3  doub Y N 498 
TRP CE3 HE3  sing N N 499 
TRP CZ2 CH2  doub Y N 500 
TRP CZ2 HZ2  sing N N 501 
TRP CZ3 CH2  sing Y N 502 
TRP CZ3 HZ3  sing N N 503 
TRP CH2 HH2  sing N N 504 
TRP OXT HXT  sing N N 505 
TYR N   CA   sing N N 506 
TYR N   H    sing N N 507 
TYR N   H2   sing N N 508 
TYR CA  C    sing N N 509 
TYR CA  CB   sing N N 510 
TYR CA  HA   sing N N 511 
TYR C   O    doub N N 512 
TYR C   OXT  sing N N 513 
TYR CB  CG   sing N N 514 
TYR CB  HB2  sing N N 515 
TYR CB  HB3  sing N N 516 
TYR CG  CD1  doub Y N 517 
TYR CG  CD2  sing Y N 518 
TYR CD1 CE1  sing Y N 519 
TYR CD1 HD1  sing N N 520 
TYR CD2 CE2  doub Y N 521 
TYR CD2 HD2  sing N N 522 
TYR CE1 CZ   doub Y N 523 
TYR CE1 HE1  sing N N 524 
TYR CE2 CZ   sing Y N 525 
TYR CE2 HE2  sing N N 526 
TYR CZ  OH   sing N N 527 
TYR OH  HH   sing N N 528 
TYR OXT HXT  sing N N 529 
VAL N   CA   sing N N 530 
VAL N   H    sing N N 531 
VAL N   H2   sing N N 532 
VAL CA  C    sing N N 533 
VAL CA  CB   sing N N 534 
VAL CA  HA   sing N N 535 
VAL C   O    doub N N 536 
VAL C   OXT  sing N N 537 
VAL CB  CG1  sing N N 538 
VAL CB  CG2  sing N N 539 
VAL CB  HB   sing N N 540 
VAL CG1 HG11 sing N N 541 
VAL CG1 HG12 sing N N 542 
VAL CG1 HG13 sing N N 543 
VAL CG2 HG21 sing N N 544 
VAL CG2 HG22 sing N N 545 
VAL CG2 HG23 sing N N 546 
VAL OXT HXT  sing N N 547 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-23 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9FG4 
_em_admin.last_update        2025-06-04 
_em_admin.map_release_date   2025-06-04 
_em_admin.title              
'Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in the long-lived symmetric resting state' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 137 mM NaCl   1 'sodium chloride'    
1 2.7 mM KCl    2 'potassium chloride' 
1 4.3 mM Na2HPO 3 'Disodium phosphate' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.25 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               6.43 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     13533 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   3141198 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? Warp      ?         
'IMAGE ACQUISITION'        ? 2  ? ? 1 EPU       ?         
MASKING                    ? 3  ? ? ? ?         ?         
'CTF CORRECTION'           ? 4  1 ? ? CTFFIND   4.1       
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?         
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?         
'MODEL FITTING'            ? 7  ? 1 ? PHENIX    ?         
OTHER                      ? 8  ? ? ? ?         ?         
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX    1.21_5207 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? cryoSPARC ?         
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? cryoSPARC ?         
CLASSIFICATION             ? 12 1 ? ? cryoSPARC ?         
RECONSTRUCTION             ? 13 1 ? ? cryoSPARC ?         
# 
_em_specimen.concentration           1 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)'                                           'United Kingdom' MC_UP_1201/15       1 
'Cancer Research UK'                                                                       'United Kingdom' DRCRPG-May23/100002 2 
'Medical Research Council (MRC, United Kingdom)'                                           'United Kingdom' MR/L009609/1        3 
'Medical Research Council (MRC, United Kingdom)'                                           'United Kingdom' MC_EX_MR/T046279/1  4 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States'  1R01-GM135550       5 
'National Science Foundation (NSF, United States)'                                         'United States'  'NeuroNex 2014862'  6 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
3 NAG 1 n 
3 NAG 2 n 
3 BMA 3 n 
3 MAN 4 n 
3 MAN 5 n 
4 NAG 1 n 
4 NAG 2 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6HUK 
# 
_atom_sites.entry_id                    9FG4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . THR A 1 47  ? 114.770 114.163 77.136  1.00 87.66  ? 12  THR A N   1 
ATOM   2     C CA  . THR A 1 47  ? 115.829 114.935 77.776  1.00 96.47  ? 12  THR A CA  1 
ATOM   3     C C   . THR A 1 47  ? 116.257 116.110 76.902  1.00 101.99 ? 12  THR A C   1 
ATOM   4     O O   . THR A 1 47  ? 116.518 117.205 77.400  1.00 102.92 ? 12  THR A O   1 
ATOM   5     C CB  . THR A 1 47  ? 117.059 114.060 78.078  1.00 95.51  ? 12  THR A CB  1 
ATOM   6     O OG1 . THR A 1 47  ? 117.620 113.579 76.850  1.00 90.78  ? 12  THR A OG1 1 
ATOM   7     C CG2 . THR A 1 47  ? 116.671 112.876 78.950  1.00 87.96  ? 12  THR A CG2 1 
ATOM   8     N N   . THR A 1 48  ? 116.332 115.865 75.591  1.00 102.23 ? 13  THR A N   1 
ATOM   9     C CA  . THR A 1 48  ? 116.729 116.915 74.658  1.00 96.62  ? 13  THR A CA  1 
ATOM   10    C C   . THR A 1 48  ? 115.733 118.068 74.661  1.00 99.34  ? 13  THR A C   1 
ATOM   11    O O   . THR A 1 48  ? 116.128 119.240 74.642  1.00 99.17  ? 13  THR A O   1 
ATOM   12    C CB  . THR A 1 48  ? 116.874 116.340 73.249  1.00 95.29  ? 13  THR A CB  1 
ATOM   13    O OG1 . THR A 1 48  ? 115.675 115.643 72.890  1.00 98.17  ? 13  THR A OG1 1 
ATOM   14    C CG2 . THR A 1 48  ? 118.050 115.379 73.189  1.00 92.06  ? 13  THR A CG2 1 
ATOM   15    N N   . VAL A 1 49  ? 114.435 117.755 74.674  1.00 101.98 ? 14  VAL A N   1 
ATOM   16    C CA  . VAL A 1 49  ? 113.411 118.795 74.720  1.00 101.81 ? 14  VAL A CA  1 
ATOM   17    C C   . VAL A 1 49  ? 113.552 119.631 75.985  1.00 98.02  ? 14  VAL A C   1 
ATOM   18    O O   . VAL A 1 49  ? 113.472 120.865 75.944  1.00 96.98  ? 14  VAL A O   1 
ATOM   19    C CB  . VAL A 1 49  ? 112.008 118.169 74.608  1.00 98.68  ? 14  VAL A CB  1 
ATOM   20    C CG1 . VAL A 1 49  ? 110.936 119.234 74.776  1.00 91.04  ? 14  VAL A CG1 1 
ATOM   21    C CG2 . VAL A 1 49  ? 111.853 117.452 73.275  1.00 95.99  ? 14  VAL A CG2 1 
ATOM   22    N N   . PHE A 1 50  ? 113.758 118.975 77.129  1.00 93.66  ? 15  PHE A N   1 
ATOM   23    C CA  . PHE A 1 50  ? 113.955 119.709 78.375  1.00 93.16  ? 15  PHE A CA  1 
ATOM   24    C C   . PHE A 1 50  ? 115.219 120.559 78.318  1.00 97.76  ? 15  PHE A C   1 
ATOM   25    O O   . PHE A 1 50  ? 115.232 121.698 78.799  1.00 98.54  ? 15  PHE A O   1 
ATOM   26    C CB  . PHE A 1 50  ? 114.018 118.727 79.545  1.00 91.80  ? 15  PHE A CB  1 
ATOM   27    C CG  . PHE A 1 50  ? 113.932 119.375 80.899  1.00 92.86  ? 15  PHE A CG  1 
ATOM   28    C CD1 . PHE A 1 50  ? 115.060 119.901 81.506  1.00 94.32  ? 15  PHE A CD1 1 
ATOM   29    C CD2 . PHE A 1 50  ? 112.728 119.432 81.578  1.00 87.11  ? 15  PHE A CD2 1 
ATOM   30    C CE1 . PHE A 1 50  ? 114.987 120.485 82.756  1.00 84.95  ? 15  PHE A CE1 1 
ATOM   31    C CE2 . PHE A 1 50  ? 112.649 120.012 82.830  1.00 84.69  ? 15  PHE A CE2 1 
ATOM   32    C CZ  . PHE A 1 50  ? 113.780 120.541 83.418  1.00 82.87  ? 15  PHE A CZ  1 
ATOM   33    N N   . THR A 1 51  ? 116.296 120.016 77.745  1.00 100.60 ? 16  THR A N   1 
ATOM   34    C CA  . THR A 1 51  ? 117.560 120.746 77.708  1.00 100.62 ? 16  THR A CA  1 
ATOM   35    C C   . THR A 1 51  ? 117.472 121.976 76.811  1.00 101.14 ? 16  THR A C   1 
ATOM   36    O O   . THR A 1 51  ? 118.033 123.029 77.138  1.00 102.14 ? 16  THR A O   1 
ATOM   37    C CB  . THR A 1 51  ? 118.688 119.823 77.244  1.00 101.62 ? 16  THR A CB  1 
ATOM   38    O OG1 . THR A 1 51  ? 118.652 118.605 77.999  1.00 96.78  ? 16  THR A OG1 1 
ATOM   39    C CG2 . THR A 1 51  ? 120.040 120.492 77.443  1.00 97.41  ? 16  THR A CG2 1 
ATOM   40    N N   . ARG A 1 52  ? 116.781 121.861 75.674  1.00 98.83  ? 17  ARG A N   1 
ATOM   41    C CA  . ARG A 1 52  ? 116.713 122.979 74.736  1.00 97.86  ? 17  ARG A CA  1 
ATOM   42    C C   . ARG A 1 52  ? 115.996 124.176 75.346  1.00 99.30  ? 17  ARG A C   1 
ATOM   43    O O   . ARG A 1 52  ? 116.389 125.325 75.114  1.00 102.84 ? 17  ARG A O   1 
ATOM   44    C CB  . ARG A 1 52  ? 116.025 122.548 73.441  1.00 103.87 ? 17  ARG A CB  1 
ATOM   45    C CG  . ARG A 1 52  ? 116.854 121.615 72.572  1.00 106.36 ? 17  ARG A CG  1 
ATOM   46    C CD  . ARG A 1 52  ? 116.336 121.590 71.141  1.00 109.88 ? 17  ARG A CD  1 
ATOM   47    N NE  . ARG A 1 52  ? 114.931 121.209 71.071  1.00 111.81 ? 17  ARG A NE  1 
ATOM   48    C CZ  . ARG A 1 52  ? 114.499 119.970 70.881  1.00 110.61 ? 17  ARG A CZ  1 
ATOM   49    N NH1 . ARG A 1 52  ? 115.341 118.959 70.740  1.00 110.95 ? 17  ARG A NH1 1 
ATOM   50    N NH2 . ARG A 1 52  ? 113.191 119.739 70.834  1.00 108.33 ? 17  ARG A NH2 1 
ATOM   51    N N   . ILE A 1 53  ? 114.929 123.927 76.109  1.00 94.66  ? 18  ILE A N   1 
ATOM   52    C CA  . ILE A 1 53  ? 114.156 125.021 76.693  1.00 96.07  ? 18  ILE A CA  1 
ATOM   53    C C   . ILE A 1 53  ? 115.029 125.867 77.610  1.00 97.75  ? 18  ILE A C   1 
ATOM   54    O O   . ILE A 1 53  ? 114.967 127.103 77.586  1.00 101.87 ? 18  ILE A O   1 
ATOM   55    C CB  . ILE A 1 53  ? 112.923 124.468 77.432  1.00 93.53  ? 18  ILE A CB  1 
ATOM   56    C CG1 . ILE A 1 53  ? 111.987 123.764 76.450  1.00 96.93  ? 18  ILE A CG1 1 
ATOM   57    C CG2 . ILE A 1 53  ? 112.189 125.584 78.153  1.00 90.87  ? 18  ILE A CG2 1 
ATOM   58    C CD1 . ILE A 1 53  ? 110.829 123.052 77.114  1.00 97.41  ? 18  ILE A CD1 1 
ATOM   59    N N   . LEU A 1 54  ? 115.856 125.217 78.432  1.00 94.35  ? 19  LEU A N   1 
ATOM   60    C CA  . LEU A 1 54  ? 116.697 125.946 79.376  1.00 96.00  ? 19  LEU A CA  1 
ATOM   61    C C   . LEU A 1 54  ? 117.669 126.871 78.651  1.00 94.73  ? 19  LEU A C   1 
ATOM   62    O O   . LEU A 1 54  ? 117.796 128.051 78.997  1.00 93.33  ? 19  LEU A O   1 
ATOM   63    C CB  . LEU A 1 54  ? 117.450 124.964 80.274  1.00 94.52  ? 19  LEU A CB  1 
ATOM   64    C CG  . LEU A 1 54  ? 116.580 124.045 81.133  1.00 87.12  ? 19  LEU A CG  1 
ATOM   65    C CD1 . LEU A 1 54  ? 117.441 123.118 81.975  1.00 83.76  ? 19  LEU A CD1 1 
ATOM   66    C CD2 . LEU A 1 54  ? 115.651 124.862 82.015  1.00 85.23  ? 19  LEU A CD2 1 
ATOM   67    N N   . ASP A 1 55  ? 118.372 126.346 77.644  1.00 95.33  ? 20  ASP A N   1 
ATOM   68    C CA  . ASP A 1 55  ? 119.327 127.165 76.903  1.00 97.50  ? 20  ASP A CA  1 
ATOM   69    C C   . ASP A 1 55  ? 118.641 128.313 76.176  1.00 100.23 ? 20  ASP A C   1 
ATOM   70    O O   . ASP A 1 55  ? 119.237 129.382 76.000  1.00 99.33  ? 20  ASP A O   1 
ATOM   71    C CB  . ASP A 1 55  ? 120.099 126.300 75.907  1.00 99.09  ? 20  ASP A CB  1 
ATOM   72    C CG  . ASP A 1 55  ? 120.666 125.046 76.540  1.00 104.60 ? 20  ASP A CG  1 
ATOM   73    O OD1 . ASP A 1 55  ? 120.285 124.735 77.688  1.00 107.41 ? 20  ASP A OD1 1 
ATOM   74    O OD2 . ASP A 1 55  ? 121.490 124.370 75.888  1.00 105.31 ? 20  ASP A OD2 1 
ATOM   75    N N   . ARG A 1 56  ? 117.395 128.114 75.745  1.00 100.50 ? 21  ARG A N   1 
ATOM   76    C CA  . ARG A 1 56  ? 116.681 129.157 75.019  1.00 101.22 ? 21  ARG A CA  1 
ATOM   77    C C   . ARG A 1 56  ? 116.147 130.245 75.944  1.00 103.97 ? 21  ARG A C   1 
ATOM   78    O O   . ARG A 1 56  ? 115.989 131.392 75.510  1.00 108.48 ? 21  ARG A O   1 
ATOM   79    C CB  . ARG A 1 56  ? 115.539 128.530 74.217  1.00 101.13 ? 21  ARG A CB  1 
ATOM   80    C CG  . ARG A 1 56  ? 114.718 129.507 73.394  1.00 106.44 ? 21  ARG A CG  1 
ATOM   81    C CD  . ARG A 1 56  ? 113.420 128.863 72.932  1.00 105.17 ? 21  ARG A CD  1 
ATOM   82    N NE  . ARG A 1 56  ? 112.622 128.374 74.050  1.00 101.21 ? 21  ARG A NE  1 
ATOM   83    C CZ  . ARG A 1 56  ? 111.941 129.146 74.886  1.00 106.56 ? 21  ARG A CZ  1 
ATOM   84    N NH1 . ARG A 1 56  ? 111.936 130.463 74.763  1.00 110.25 ? 21  ARG A NH1 1 
ATOM   85    N NH2 . ARG A 1 56  ? 111.249 128.582 75.872  1.00 107.85 ? 21  ARG A NH2 1 
ATOM   86    N N   . LEU A 1 57  ? 115.871 129.911 77.208  1.00 100.36 ? 22  LEU A N   1 
ATOM   87    C CA  . LEU A 1 57  ? 115.147 130.829 78.085  1.00 97.31  ? 22  LEU A CA  1 
ATOM   88    C C   . LEU A 1 57  ? 115.891 132.149 78.253  1.00 97.32  ? 22  LEU A C   1 
ATOM   89    O O   . LEU A 1 57  ? 115.304 133.228 78.115  1.00 95.50  ? 22  LEU A O   1 
ATOM   90    C CB  . LEU A 1 57  ? 114.902 130.176 79.445  1.00 95.25  ? 22  LEU A CB  1 
ATOM   91    C CG  . LEU A 1 57  ? 113.611 129.369 79.583  1.00 95.36  ? 22  LEU A CG  1 
ATOM   92    C CD1 . LEU A 1 57  ? 113.569 128.651 80.920  1.00 94.86  ? 22  LEU A CD1 1 
ATOM   93    C CD2 . LEU A 1 57  ? 112.397 130.266 79.412  1.00 83.16  ? 22  LEU A CD2 1 
ATOM   94    N N   . LEU A 1 58  ? 117.189 132.082 78.550  1.00 96.40  ? 23  LEU A N   1 
ATOM   95    C CA  . LEU A 1 58  ? 117.981 133.262 78.866  1.00 92.44  ? 23  LEU A CA  1 
ATOM   96    C C   . LEU A 1 58  ? 118.529 133.964 77.630  1.00 93.17  ? 23  LEU A C   1 
ATOM   97    O O   . LEU A 1 58  ? 119.506 134.713 77.738  1.00 92.74  ? 23  LEU A O   1 
ATOM   98    C CB  . LEU A 1 58  ? 119.125 132.886 79.809  1.00 90.87  ? 23  LEU A CB  1 
ATOM   99    C CG  . LEU A 1 58  ? 118.675 132.182 81.087  1.00 92.57  ? 23  LEU A CG  1 
ATOM   100   C CD1 . LEU A 1 58  ? 119.869 131.752 81.922  1.00 89.51  ? 23  LEU A CD1 1 
ATOM   101   C CD2 . LEU A 1 58  ? 117.757 133.090 81.880  1.00 82.47  ? 23  LEU A CD2 1 
ATOM   102   N N   . ASP A 1 59  ? 117.929 133.744 76.464  1.00 96.83  ? 24  ASP A N   1 
ATOM   103   C CA  . ASP A 1 59  ? 118.394 134.374 75.233  1.00 101.81 ? 24  ASP A CA  1 
ATOM   104   C C   . ASP A 1 59  ? 117.881 135.809 75.218  1.00 100.99 ? 24  ASP A C   1 
ATOM   105   O O   . ASP A 1 59  ? 116.671 136.042 75.127  1.00 96.22  ? 24  ASP A O   1 
ATOM   106   C CB  . ASP A 1 59  ? 117.910 133.592 74.015  1.00 103.60 ? 24  ASP A CB  1 
ATOM   107   C CG  . ASP A 1 59  ? 118.571 134.044 72.724  1.00 109.05 ? 24  ASP A CG  1 
ATOM   108   O OD1 . ASP A 1 59  ? 119.232 135.104 72.719  1.00 105.00 ? 24  ASP A OD1 1 
ATOM   109   O OD2 . ASP A 1 59  ? 118.430 133.331 71.709  1.00 118.25 ? 24  ASP A OD2 1 
ATOM   110   N N   . GLY A 1 60  ? 118.794 136.773 75.313  1.00 101.35 ? 25  GLY A N   1 
ATOM   111   C CA  . GLY A 1 60  ? 118.400 138.164 75.353  1.00 96.81  ? 25  GLY A CA  1 
ATOM   112   C C   . GLY A 1 60  ? 117.834 138.622 76.676  1.00 96.46  ? 25  GLY A C   1 
ATOM   113   O O   . GLY A 1 60  ? 117.279 139.724 76.748  1.00 99.79  ? 25  GLY A O   1 
ATOM   114   N N   . TYR A 1 61  ? 117.958 137.813 77.724  1.00 90.59  ? 26  TYR A N   1 
ATOM   115   C CA  . TYR A 1 61  ? 117.390 138.125 79.026  1.00 81.49  ? 26  TYR A CA  1 
ATOM   116   C C   . TYR A 1 61  ? 118.365 138.978 79.828  1.00 78.88  ? 26  TYR A C   1 
ATOM   117   O O   . TYR A 1 61  ? 119.540 138.623 79.969  1.00 81.83  ? 26  TYR A O   1 
ATOM   118   C CB  . TYR A 1 61  ? 117.072 136.824 79.767  1.00 80.69  ? 26  TYR A CB  1 
ATOM   119   C CG  . TYR A 1 61  ? 116.452 136.971 81.138  1.00 75.34  ? 26  TYR A CG  1 
ATOM   120   C CD1 . TYR A 1 61  ? 117.242 137.172 82.263  1.00 67.01  ? 26  TYR A CD1 1 
ATOM   121   C CD2 . TYR A 1 61  ? 115.078 136.874 81.312  1.00 72.49  ? 26  TYR A CD2 1 
ATOM   122   C CE1 . TYR A 1 61  ? 116.679 137.293 83.518  1.00 61.86  ? 26  TYR A CE1 1 
ATOM   123   C CE2 . TYR A 1 61  ? 114.507 136.993 82.564  1.00 69.53  ? 26  TYR A CE2 1 
ATOM   124   C CZ  . TYR A 1 61  ? 115.313 137.202 83.662  1.00 63.92  ? 26  TYR A CZ  1 
ATOM   125   O OH  . TYR A 1 61  ? 114.750 137.320 84.911  1.00 60.12  ? 26  TYR A OH  1 
ATOM   126   N N   . ASP A 1 62  ? 117.873 140.101 80.347  1.00 75.15  ? 27  ASP A N   1 
ATOM   127   C CA  . ASP A 1 62  ? 118.651 141.000 81.194  1.00 68.56  ? 27  ASP A CA  1 
ATOM   128   C C   . ASP A 1 62  ? 118.150 140.840 82.625  1.00 61.59  ? 27  ASP A C   1 
ATOM   129   O O   . ASP A 1 62  ? 117.037 141.268 82.948  1.00 59.61  ? 27  ASP A O   1 
ATOM   130   C CB  . ASP A 1 62  ? 118.527 142.446 80.720  1.00 62.14  ? 27  ASP A CB  1 
ATOM   131   C CG  . ASP A 1 62  ? 119.594 143.346 81.308  1.00 56.21  ? 27  ASP A CG  1 
ATOM   132   O OD1 . ASP A 1 62  ? 120.553 142.818 81.910  1.00 51.36  ? 27  ASP A OD1 1 
ATOM   133   O OD2 . ASP A 1 62  ? 119.476 144.581 81.167  1.00 56.00  ? 27  ASP A OD2 1 
ATOM   134   N N   . ASN A 1 63  ? 118.968 140.226 83.478  1.00 60.47  ? 28  ASN A N   1 
ATOM   135   C CA  . ASN A 1 63  ? 118.572 139.992 84.860  1.00 56.58  ? 28  ASN A CA  1 
ATOM   136   C C   . ASN A 1 63  ? 118.749 141.208 85.758  1.00 52.08  ? 28  ASN A C   1 
ATOM   137   O O   . ASN A 1 63  ? 118.348 141.154 86.925  1.00 50.84  ? 28  ASN A O   1 
ATOM   138   C CB  . ASN A 1 63  ? 119.365 138.814 85.429  1.00 57.17  ? 28  ASN A CB  1 
ATOM   139   C CG  . ASN A 1 63  ? 120.849 139.100 85.511  1.00 59.25  ? 28  ASN A CG  1 
ATOM   140   O OD1 . ASN A 1 63  ? 121.368 139.954 84.793  1.00 60.96  ? 28  ASN A OD1 1 
ATOM   141   N ND2 . ASN A 1 63  ? 121.544 138.377 86.380  1.00 62.21  ? 28  ASN A ND2 1 
ATOM   142   N N   . ARG A 1 64  ? 119.339 142.293 85.257  1.00 53.14  ? 29  ARG A N   1 
ATOM   143   C CA  . ARG A 1 64  ? 119.459 143.518 86.036  1.00 53.23  ? 29  ARG A CA  1 
ATOM   144   C C   . ARG A 1 64  ? 118.190 144.361 86.035  1.00 48.05  ? 29  ARG A C   1 
ATOM   145   O O   . ARG A 1 64  ? 118.129 145.355 86.765  1.00 42.72  ? 29  ARG A O   1 
ATOM   146   C CB  . ARG A 1 64  ? 120.634 144.355 85.522  1.00 49.91  ? 29  ARG A CB  1 
ATOM   147   C CG  . ARG A 1 64  ? 121.971 143.636 85.589  1.00 46.68  ? 29  ARG A CG  1 
ATOM   148   C CD  . ARG A 1 64  ? 123.082 144.442 84.939  1.00 43.24  ? 29  ARG A CD  1 
ATOM   149   N NE  . ARG A 1 64  ? 122.827 144.695 83.526  1.00 48.18  ? 29  ARG A NE  1 
ATOM   150   C CZ  . ARG A 1 64  ? 123.718 145.200 82.684  1.00 53.24  ? 29  ARG A CZ  1 
ATOM   151   N NH1 . ARG A 1 64  ? 124.944 145.505 83.076  1.00 49.17  ? 29  ARG A NH1 1 
ATOM   152   N NH2 . ARG A 1 64  ? 123.370 145.402 81.417  1.00 55.09  ? 29  ARG A NH2 1 
ATOM   153   N N   . LEU A 1 65  ? 117.184 143.994 85.246  1.00 48.73  ? 30  LEU A N   1 
ATOM   154   C CA  . LEU A 1 65  ? 115.950 144.759 85.131  1.00 49.79  ? 30  LEU A CA  1 
ATOM   155   C C   . LEU A 1 65  ? 114.767 143.929 85.606  1.00 48.77  ? 30  LEU A C   1 
ATOM   156   O O   . LEU A 1 65  ? 114.606 142.776 85.193  1.00 47.12  ? 30  LEU A O   1 
ATOM   157   C CB  . LEU A 1 65  ? 115.724 145.219 83.690  1.00 53.20  ? 30  LEU A CB  1 
ATOM   158   C CG  . LEU A 1 65  ? 116.940 145.806 82.972  1.00 47.50  ? 30  LEU A CG  1 
ATOM   159   C CD1 . LEU A 1 65  ? 116.580 146.186 81.547  1.00 49.67  ? 30  LEU A CD1 1 
ATOM   160   C CD2 . LEU A 1 65  ? 117.497 147.000 83.729  1.00 41.82  ? 30  LEU A CD2 1 
ATOM   161   N N   . ARG A 1 66  ? 113.945 144.520 86.470  1.00 47.36  ? 31  ARG A N   1 
ATOM   162   C CA  . ARG A 1 66  ? 112.770 143.844 86.988  1.00 47.04  ? 31  ARG A CA  1 
ATOM   163   C C   . ARG A 1 66  ? 111.723 143.695 85.884  1.00 55.49  ? 31  ARG A C   1 
ATOM   164   O O   . ARG A 1 66  ? 111.722 144.453 84.912  1.00 60.47  ? 31  ARG A O   1 
ATOM   165   C CB  . ARG A 1 66  ? 112.177 144.630 88.153  1.00 42.56  ? 31  ARG A CB  1 
ATOM   166   C CG  . ARG A 1 66  ? 111.743 146.031 87.762  1.00 54.41  ? 31  ARG A CG  1 
ATOM   167   C CD  . ARG A 1 66  ? 110.908 146.693 88.839  1.00 56.97  ? 31  ARG A CD  1 
ATOM   168   N NE  . ARG A 1 66  ? 110.344 147.952 88.369  1.00 60.30  ? 31  ARG A NE  1 
ATOM   169   C CZ  . ARG A 1 66  ? 109.211 148.056 87.689  1.00 61.30  ? 31  ARG A CZ  1 
ATOM   170   N NH1 . ARG A 1 66  ? 108.504 146.988 87.356  1.00 55.45  ? 31  ARG A NH1 1 
ATOM   171   N NH2 . ARG A 1 66  ? 108.780 149.260 87.326  1.00 65.51  ? 31  ARG A NH2 1 
ATOM   172   N N   . PRO A 1 67  ? 110.837 142.705 86.000  1.00 51.89  ? 32  PRO A N   1 
ATOM   173   C CA  . PRO A 1 67  ? 109.777 142.547 84.997  1.00 50.00  ? 32  PRO A CA  1 
ATOM   174   C C   . PRO A 1 67  ? 108.913 143.794 84.894  1.00 53.42  ? 32  PRO A C   1 
ATOM   175   O O   . PRO A 1 67  ? 108.572 144.422 85.899  1.00 49.47  ? 32  PRO A O   1 
ATOM   176   C CB  . PRO A 1 67  ? 108.971 141.351 85.514  1.00 49.43  ? 32  PRO A CB  1 
ATOM   177   C CG  . PRO A 1 67  ? 109.898 140.614 86.407  1.00 51.65  ? 32  PRO A CG  1 
ATOM   178   C CD  . PRO A 1 67  ? 110.811 141.633 87.009  1.00 50.59  ? 32  PRO A CD  1 
ATOM   179   N N   . GLY A 1 68  ? 108.556 144.146 83.661  1.00 64.96  ? 33  GLY A N   1 
ATOM   180   C CA  . GLY A 1 68  ? 107.738 145.324 83.435  1.00 73.00  ? 33  GLY A CA  1 
ATOM   181   C C   . GLY A 1 68  ? 108.399 146.617 83.851  1.00 71.86  ? 33  GLY A C   1 
ATOM   182   O O   . GLY A 1 68  ? 107.713 147.533 84.318  1.00 70.65  ? 33  GLY A O   1 
ATOM   183   N N   . LEU A 1 69  ? 109.719 146.714 83.703  1.00 70.56  ? 34  LEU A N   1 
ATOM   184   C CA  . LEU A 1 69  ? 110.429 147.927 84.085  1.00 68.31  ? 34  LEU A CA  1 
ATOM   185   C C   . LEU A 1 69  ? 109.931 149.113 83.269  1.00 73.60  ? 34  LEU A C   1 
ATOM   186   O O   . LEU A 1 69  ? 109.804 149.032 82.045  1.00 72.50  ? 34  LEU A O   1 
ATOM   187   C CB  . LEU A 1 69  ? 111.933 147.742 83.892  1.00 58.24  ? 34  LEU A CB  1 
ATOM   188   C CG  . LEU A 1 69  ? 112.787 148.986 84.136  1.00 62.09  ? 34  LEU A CG  1 
ATOM   189   C CD1 . LEU A 1 69  ? 112.607 149.480 85.563  1.00 64.67  ? 34  LEU A CD1 1 
ATOM   190   C CD2 . LEU A 1 69  ? 114.249 148.701 83.849  1.00 61.78  ? 34  LEU A CD2 1 
ATOM   191   N N   . GLY A 1 70  ? 109.648 150.216 83.958  1.00 78.89  ? 35  GLY A N   1 
ATOM   192   C CA  . GLY A 1 70  ? 109.151 151.408 83.299  1.00 78.64  ? 35  GLY A CA  1 
ATOM   193   C C   . GLY A 1 70  ? 107.812 151.232 82.626  1.00 82.68  ? 35  GLY A C   1 
ATOM   194   O O   . GLY A 1 70  ? 107.424 152.067 81.805  1.00 80.84  ? 35  GLY A O   1 
ATOM   195   N N   . GLU A 1 71  ? 107.092 150.168 82.950  1.00 79.70  ? 36  GLU A N   1 
ATOM   196   C CA  . GLU A 1 71  ? 105.819 149.859 82.312  1.00 83.07  ? 36  GLU A CA  1 
ATOM   197   C C   . GLU A 1 71  ? 104.698 149.618 83.312  1.00 84.30  ? 36  GLU A C   1 
ATOM   198   O O   . GLU A 1 71  ? 103.557 150.006 83.048  1.00 86.52  ? 36  GLU A O   1 
ATOM   199   C CB  . GLU A 1 71  ? 105.991 148.637 81.393  1.00 81.19  ? 36  GLU A CB  1 
ATOM   200   C CG  . GLU A 1 71  ? 104.723 148.178 80.700  1.00 83.23  ? 36  GLU A CG  1 
ATOM   201   C CD  . GLU A 1 71  ? 104.916 146.877 79.948  1.00 84.53  ? 36  GLU A CD  1 
ATOM   202   O OE1 . GLU A 1 71  ? 106.080 146.463 79.764  1.00 79.44  ? 36  GLU A OE1 1 
ATOM   203   O OE2 . GLU A 1 71  ? 103.904 146.266 79.543  1.00 87.89  ? 36  GLU A OE2 1 
ATOM   204   N N   . ARG A 1 72  ? 104.994 149.010 84.456  1.00 81.22  ? 37  ARG A N   1 
ATOM   205   C CA  . ARG A 1 72  ? 103.984 148.687 85.460  1.00 80.65  ? 37  ARG A CA  1 
ATOM   206   C C   . ARG A 1 72  ? 104.704 148.256 86.733  1.00 69.14  ? 37  ARG A C   1 
ATOM   207   O O   . ARG A 1 72  ? 105.938 148.236 86.796  1.00 67.42  ? 37  ARG A O   1 
ATOM   208   C CB  . ARG A 1 72  ? 103.032 147.594 84.969  1.00 81.21  ? 37  ARG A CB  1 
ATOM   209   C CG  . ARG A 1 72  ? 103.716 146.267 84.685  1.00 80.27  ? 37  ARG A CG  1 
ATOM   210   C CD  . ARG A 1 72  ? 102.733 145.234 84.163  1.00 78.41  ? 37  ARG A CD  1 
ATOM   211   N NE  . ARG A 1 72  ? 103.370 143.941 83.943  1.00 81.32  ? 37  ARG A NE  1 
ATOM   212   C CZ  . ARG A 1 72  ? 104.062 143.621 82.858  1.00 84.45  ? 37  ARG A CZ  1 
ATOM   213   N NH1 . ARG A 1 72  ? 104.226 144.480 81.865  1.00 83.57  ? 37  ARG A NH1 1 
ATOM   214   N NH2 . ARG A 1 72  ? 104.600 142.409 82.766  1.00 83.80  ? 37  ARG A NH2 1 
ATOM   215   N N   . VAL A 1 73  ? 103.919 147.915 87.752  1.00 58.77  ? 38  VAL A N   1 
ATOM   216   C CA  . VAL A 1 73  ? 104.437 147.494 89.048  1.00 55.05  ? 38  VAL A CA  1 
ATOM   217   C C   . VAL A 1 73  ? 104.489 145.974 89.092  1.00 55.14  ? 38  VAL A C   1 
ATOM   218   O O   . VAL A 1 73  ? 103.508 145.300 88.753  1.00 56.81  ? 38  VAL A O   1 
ATOM   219   C CB  . VAL A 1 73  ? 103.576 148.048 90.195  1.00 57.19  ? 38  VAL A CB  1 
ATOM   220   C CG1 . VAL A 1 73  ? 104.230 147.756 91.532  1.00 49.15  ? 38  VAL A CG1 1 
ATOM   221   C CG2 . VAL A 1 73  ? 103.360 149.542 90.016  1.00 57.51  ? 38  VAL A CG2 1 
ATOM   222   N N   . THR A 1 74  ? 105.632 145.433 89.507  1.00 55.89  ? 39  THR A N   1 
ATOM   223   C CA  . THR A 1 74  ? 105.796 143.992 89.666  1.00 51.27  ? 39  THR A CA  1 
ATOM   224   C C   . THR A 1 74  ? 105.165 143.537 90.977  1.00 47.17  ? 39  THR A C   1 
ATOM   225   O O   . THR A 1 74  ? 105.620 143.927 92.058  1.00 46.53  ? 39  THR A O   1 
ATOM   226   C CB  . THR A 1 74  ? 107.275 143.615 89.626  1.00 50.84  ? 39  THR A CB  1 
ATOM   227   O OG1 . THR A 1 74  ? 107.909 144.278 88.525  1.00 60.01  ? 39  THR A OG1 1 
ATOM   228   C CG2 . THR A 1 74  ? 107.432 142.112 89.466  1.00 42.48  ? 39  THR A CG2 1 
ATOM   229   N N   . GLU A 1 75  ? 104.125 142.714 90.887  1.00 50.36  ? 40  GLU A N   1 
ATOM   230   C CA  . GLU A 1 75  ? 103.398 142.238 92.056  1.00 48.91  ? 40  GLU A CA  1 
ATOM   231   C C   . GLU A 1 75  ? 103.948 140.880 92.475  1.00 42.44  ? 40  GLU A C   1 
ATOM   232   O O   . GLU A 1 75  ? 104.014 139.955 91.659  1.00 42.53  ? 40  GLU A O   1 
ATOM   233   C CB  . GLU A 1 75  ? 101.902 142.142 91.755  1.00 47.67  ? 40  GLU A CB  1 
ATOM   234   C CG  . GLU A 1 75  ? 101.046 141.714 92.930  1.00 50.61  ? 40  GLU A CG  1 
ATOM   235   C CD  . GLU A 1 75  ? 99.616  141.426 92.519  1.00 65.56  ? 40  GLU A CD  1 
ATOM   236   O OE1 . GLU A 1 75  ? 99.262  141.721 91.358  1.00 69.85  ? 40  GLU A OE1 1 
ATOM   237   O OE2 . GLU A 1 75  ? 98.850  140.894 93.348  1.00 70.39  ? 40  GLU A OE2 1 
ATOM   238   N N   . VAL A 1 76  ? 104.334 140.763 93.743  1.00 34.55  ? 41  VAL A N   1 
ATOM   239   C CA  . VAL A 1 76  ? 104.912 139.538 94.286  1.00 29.78  ? 41  VAL A CA  1 
ATOM   240   C C   . VAL A 1 76  ? 103.979 138.973 95.347  1.00 28.67  ? 41  VAL A C   1 
ATOM   241   O O   . VAL A 1 76  ? 103.717 139.627 96.363  1.00 29.22  ? 41  VAL A O   1 
ATOM   242   C CB  . VAL A 1 76  ? 106.314 139.779 94.865  1.00 27.43  ? 41  VAL A CB  1 
ATOM   243   C CG1 . VAL A 1 76  ? 106.904 138.478 95.372  1.00 26.44  ? 41  VAL A CG1 1 
ATOM   244   C CG2 . VAL A 1 76  ? 107.219 140.397 93.812  1.00 26.15  ? 41  VAL A CG2 1 
ATOM   245   N N   . LYS A 1 77  ? 103.485 137.760 95.116  1.00 30.72  ? 42  LYS A N   1 
ATOM   246   C CA  . LYS A 1 77  ? 102.657 137.043 96.078  1.00 28.93  ? 42  LYS A CA  1 
ATOM   247   C C   . LYS A 1 77  ? 103.528 136.101 96.899  1.00 25.08  ? 42  LYS A C   1 
ATOM   248   O O   . LYS A 1 77  ? 104.268 135.287 96.337  1.00 29.41  ? 42  LYS A O   1 
ATOM   249   C CB  . LYS A 1 77  ? 101.539 136.265 95.383  1.00 30.68  ? 42  LYS A CB  1 
ATOM   250   C CG  . LYS A 1 77  ? 100.526 137.140 94.669  1.00 36.92  ? 42  LYS A CG  1 
ATOM   251   C CD  . LYS A 1 77  ? 99.337  136.323 94.199  1.00 45.27  ? 42  LYS A CD  1 
ATOM   252   C CE  . LYS A 1 77  ? 98.377  137.170 93.383  1.00 60.45  ? 42  LYS A CE  1 
ATOM   253   N NZ  . LYS A 1 77  ? 97.878  138.335 94.164  1.00 65.96  ? 42  LYS A NZ  1 
ATOM   254   N N   . THR A 1 78  ? 103.439 136.210 98.222  1.00 20.37  ? 43  THR A N   1 
ATOM   255   C CA  . THR A 1 78  ? 104.334 135.502 99.125  1.00 20.13  ? 43  THR A CA  1 
ATOM   256   C C   . THR A 1 78  ? 103.529 134.754 100.175 1.00 19.81  ? 43  THR A C   1 
ATOM   257   O O   . THR A 1 78  ? 102.433 135.171 100.555 1.00 28.46  ? 43  THR A O   1 
ATOM   258   C CB  . THR A 1 78  ? 105.309 136.453 99.830  1.00 20.69  ? 43  THR A CB  1 
ATOM   259   O OG1 . THR A 1 78  ? 104.598 137.232 100.799 1.00 21.22  ? 43  THR A OG1 1 
ATOM   260   C CG2 . THR A 1 78  ? 105.972 137.386 98.830  1.00 25.04  ? 43  THR A CG2 1 
ATOM   261   N N   . ASP A 1 79  ? 104.080 133.630 100.626 1.00 17.82  ? 44  ASP A N   1 
ATOM   262   C CA  . ASP A 1 79  ? 103.533 132.899 101.759 1.00 18.01  ? 44  ASP A CA  1 
ATOM   263   C C   . ASP A 1 79  ? 104.672 132.205 102.488 1.00 16.96  ? 44  ASP A C   1 
ATOM   264   O O   . ASP A 1 79  ? 105.737 131.955 101.920 1.00 19.86  ? 44  ASP A O   1 
ATOM   265   C CB  . ASP A 1 79  ? 102.475 131.878 101.324 1.00 25.12  ? 44  ASP A CB  1 
ATOM   266   C CG  . ASP A 1 79  ? 102.989 130.918 100.275 1.00 28.75  ? 44  ASP A CG  1 
ATOM   267   O OD1 . ASP A 1 79  ? 103.468 131.388 99.223  1.00 30.80  ? 44  ASP A OD1 1 
ATOM   268   O OD2 . ASP A 1 79  ? 102.914 129.692 100.500 1.00 27.88  ? 44  ASP A OD2 1 
ATOM   269   N N   . ILE A 1 80  ? 104.438 131.902 103.761 1.00 16.10  ? 45  ILE A N   1 
ATOM   270   C CA  . ILE A 1 80  ? 105.449 131.315 104.630 1.00 14.53  ? 45  ILE A CA  1 
ATOM   271   C C   . ILE A 1 80  ? 104.879 130.059 105.268 1.00 20.57  ? 45  ILE A C   1 
ATOM   272   O O   . ILE A 1 80  ? 103.707 130.027 105.660 1.00 28.57  ? 45  ILE A O   1 
ATOM   273   C CB  . ILE A 1 80  ? 105.913 132.307 105.717 1.00 12.69  ? 45  ILE A CB  1 
ATOM   274   C CG1 . ILE A 1 80  ? 106.275 133.657 105.102 1.00 13.68  ? 45  ILE A CG1 1 
ATOM   275   C CG2 . ILE A 1 80  ? 107.084 131.746 106.492 1.00 12.08  ? 45  ILE A CG2 1 
ATOM   276   C CD1 . ILE A 1 80  ? 106.656 134.700 106.122 1.00 14.19  ? 45  ILE A CD1 1 
ATOM   277   N N   . PHE A 1 81  ? 105.704 129.019 105.359 1.00 18.68  ? 46  PHE A N   1 
ATOM   278   C CA  . PHE A 1 81  ? 105.376 127.808 106.106 1.00 20.83  ? 46  PHE A CA  1 
ATOM   279   C C   . PHE A 1 81  ? 106.438 127.643 107.186 1.00 19.86  ? 46  PHE A C   1 
ATOM   280   O O   . PHE A 1 81  ? 107.560 127.212 106.903 1.00 22.43  ? 46  PHE A O   1 
ATOM   281   C CB  . PHE A 1 81  ? 105.319 126.598 105.174 1.00 23.26  ? 46  PHE A CB  1 
ATOM   282   C CG  . PHE A 1 81  ? 105.015 125.301 105.870 1.00 28.46  ? 46  PHE A CG  1 
ATOM   283   C CD1 . PHE A 1 81  ? 103.705 124.909 106.087 1.00 34.11  ? 46  PHE A CD1 1 
ATOM   284   C CD2 . PHE A 1 81  ? 106.036 124.465 106.287 1.00 24.14  ? 46  PHE A CD2 1 
ATOM   285   C CE1 . PHE A 1 81  ? 103.419 123.715 106.719 1.00 36.57  ? 46  PHE A CE1 1 
ATOM   286   C CE2 . PHE A 1 81  ? 105.757 123.269 106.920 1.00 25.64  ? 46  PHE A CE2 1 
ATOM   287   C CZ  . PHE A 1 81  ? 104.447 122.894 107.136 1.00 33.39  ? 46  PHE A CZ  1 
ATOM   288   N N   . VAL A 1 82  ? 106.086 127.984 108.423 1.00 16.14  ? 47  VAL A N   1 
ATOM   289   C CA  . VAL A 1 82  ? 107.025 127.916 109.537 1.00 13.68  ? 47  VAL A CA  1 
ATOM   290   C C   . VAL A 1 82  ? 107.168 126.459 109.962 1.00 16.91  ? 47  VAL A C   1 
ATOM   291   O O   . VAL A 1 82  ? 106.237 125.872 110.516 1.00 20.37  ? 47  VAL A O   1 
ATOM   292   C CB  . VAL A 1 82  ? 106.568 128.792 110.708 1.00 14.83  ? 47  VAL A CB  1 
ATOM   293   C CG1 . VAL A 1 82  ? 107.616 128.800 111.804 1.00 16.22  ? 47  VAL A CG1 1 
ATOM   294   C CG2 . VAL A 1 82  ? 106.284 130.205 110.230 1.00 14.34  ? 47  VAL A CG2 1 
ATOM   295   N N   . THR A 1 83  ? 108.334 125.867 109.699 1.00 18.49  ? 48  THR A N   1 
ATOM   296   C CA  . THR A 1 83  ? 108.554 124.488 110.118 1.00 21.79  ? 48  THR A CA  1 
ATOM   297   C C   . THR A 1 83  ? 108.856 124.392 111.604 1.00 18.59  ? 48  THR A C   1 
ATOM   298   O O   . THR A 1 83  ? 108.537 123.379 112.235 1.00 20.64  ? 48  THR A O   1 
ATOM   299   C CB  . THR A 1 83  ? 109.696 123.856 109.325 1.00 19.89  ? 48  THR A CB  1 
ATOM   300   O OG1 . THR A 1 83  ? 110.949 124.358 109.804 1.00 21.12  ? 48  THR A OG1 1 
ATOM   301   C CG2 . THR A 1 83  ? 109.557 124.183 107.862 1.00 16.57  ? 48  THR A CG2 1 
ATOM   302   N N   . SER A 1 84  ? 109.462 125.429 112.175 1.00 15.92  ? 49  SER A N   1 
ATOM   303   C CA  . SER A 1 84  ? 109.774 125.440 113.599 1.00 19.97  ? 49  SER A CA  1 
ATOM   304   C C   . SER A 1 84  ? 110.028 126.872 114.032 1.00 17.97  ? 49  SER A C   1 
ATOM   305   O O   . SER A 1 84  ? 110.979 127.500 113.558 1.00 17.79  ? 49  SER A O   1 
ATOM   306   C CB  . SER A 1 84  ? 110.987 124.571 113.893 1.00 24.76  ? 49  SER A CB  1 
ATOM   307   O OG  . SER A 1 84  ? 112.074 124.916 113.054 1.00 20.94  ? 49  SER A OG  1 
ATOM   308   N N   . PHE A 1 85  ? 109.197 127.381 114.934 1.00 20.13  ? 50  PHE A N   1 
ATOM   309   C CA  . PHE A 1 85  ? 109.420 128.694 115.529 1.00 21.10  ? 50  PHE A CA  1 
ATOM   310   C C   . PHE A 1 85  ? 110.495 128.525 116.593 1.00 23.78  ? 50  PHE A C   1 
ATOM   311   O O   . PHE A 1 85  ? 110.208 128.128 117.724 1.00 28.06  ? 50  PHE A O   1 
ATOM   312   C CB  . PHE A 1 85  ? 108.127 129.250 116.111 1.00 26.61  ? 50  PHE A CB  1 
ATOM   313   C CG  . PHE A 1 85  ? 108.210 130.697 116.504 1.00 29.28  ? 50  PHE A CG  1 
ATOM   314   C CD1 . PHE A 1 85  ? 108.035 131.693 115.560 1.00 27.39  ? 50  PHE A CD1 1 
ATOM   315   C CD2 . PHE A 1 85  ? 108.460 131.061 117.814 1.00 30.36  ? 50  PHE A CD2 1 
ATOM   316   C CE1 . PHE A 1 85  ? 108.110 133.024 115.917 1.00 26.48  ? 50  PHE A CE1 1 
ATOM   317   C CE2 . PHE A 1 85  ? 108.535 132.391 118.176 1.00 32.61  ? 50  PHE A CE2 1 
ATOM   318   C CZ  . PHE A 1 85  ? 108.359 133.372 117.226 1.00 30.43  ? 50  PHE A CZ  1 
ATOM   319   N N   . GLY A 1 86  ? 111.744 128.799 116.219 1.00 21.94  ? 51  GLY A N   1 
ATOM   320   C CA  . GLY A 1 86  ? 112.890 128.464 117.032 1.00 19.23  ? 51  GLY A CA  1 
ATOM   321   C C   . GLY A 1 86  ? 112.919 129.182 118.365 1.00 21.47  ? 51  GLY A C   1 
ATOM   322   O O   . GLY A 1 86  ? 111.968 129.866 118.752 1.00 22.35  ? 51  GLY A O   1 
ATOM   323   N N   . PRO A 1 87  ? 114.031 129.060 119.085 1.00 20.34  ? 52  PRO A N   1 
ATOM   324   C CA  . PRO A 1 87  ? 114.101 129.651 120.424 1.00 23.74  ? 52  PRO A CA  1 
ATOM   325   C C   . PRO A 1 87  ? 114.043 131.169 120.385 1.00 25.12  ? 52  PRO A C   1 
ATOM   326   O O   . PRO A 1 87  ? 114.445 131.811 119.412 1.00 26.10  ? 52  PRO A O   1 
ATOM   327   C CB  . PRO A 1 87  ? 115.454 129.163 120.955 1.00 22.46  ? 52  PRO A CB  1 
ATOM   328   C CG  . PRO A 1 87  ? 116.257 128.881 119.732 1.00 18.48  ? 52  PRO A CG  1 
ATOM   329   C CD  . PRO A 1 87  ? 115.284 128.387 118.706 1.00 17.05  ? 52  PRO A CD  1 
ATOM   330   N N   . VAL A 1 88  ? 113.533 131.735 121.474 1.00 27.69  ? 53  VAL A N   1 
ATOM   331   C CA  . VAL A 1 88  ? 113.472 133.175 121.688 1.00 29.08  ? 53  VAL A CA  1 
ATOM   332   C C   . VAL A 1 88  ? 114.471 133.529 122.779 1.00 36.03  ? 53  VAL A C   1 
ATOM   333   O O   . VAL A 1 88  ? 114.511 132.870 123.825 1.00 45.61  ? 53  VAL A O   1 
ATOM   334   C CB  . VAL A 1 88  ? 112.050 133.621 122.069 1.00 29.17  ? 53  VAL A CB  1 
ATOM   335   C CG1 . VAL A 1 88  ? 112.021 135.105 122.360 1.00 32.85  ? 53  VAL A CG1 1 
ATOM   336   C CG2 . VAL A 1 88  ? 111.068 133.264 120.964 1.00 25.96  ? 53  VAL A CG2 1 
ATOM   337   N N   . SER A 1 89  ? 115.274 134.564 122.543 1.00 35.65  ? 54  SER A N   1 
ATOM   338   C CA  . SER A 1 89  ? 116.307 134.980 123.486 1.00 43.42  ? 54  SER A CA  1 
ATOM   339   C C   . SER A 1 89  ? 115.921 136.322 124.096 1.00 47.02  ? 54  SER A C   1 
ATOM   340   O O   . SER A 1 89  ? 115.895 137.343 123.402 1.00 47.71  ? 54  SER A O   1 
ATOM   341   C CB  . SER A 1 89  ? 117.666 135.068 122.796 1.00 41.67  ? 54  SER A CB  1 
ATOM   342   O OG  . SER A 1 89  ? 118.690 135.344 123.735 1.00 49.19  ? 54  SER A OG  1 
ATOM   343   N N   . ASP A 1 90  ? 115.621 136.315 125.398 1.00 49.41  ? 55  ASP A N   1 
ATOM   344   C CA  . ASP A 1 90  ? 115.314 137.558 126.097 1.00 51.01  ? 55  ASP A CA  1 
ATOM   345   C C   . ASP A 1 90  ? 116.555 138.432 126.238 1.00 59.27  ? 55  ASP A C   1 
ATOM   346   O O   . ASP A 1 90  ? 116.471 139.662 126.141 1.00 61.73  ? 55  ASP A O   1 
ATOM   347   C CB  . ASP A 1 90  ? 114.718 137.255 127.472 1.00 51.86  ? 55  ASP A CB  1 
ATOM   348   C CG  . ASP A 1 90  ? 113.473 136.394 127.393 1.00 49.55  ? 55  ASP A CG  1 
ATOM   349   O OD1 . ASP A 1 90  ? 112.510 136.797 126.709 1.00 49.72  ? 55  ASP A OD1 1 
ATOM   350   O OD2 . ASP A 1 90  ? 113.457 135.313 128.018 1.00 43.75  ? 55  ASP A OD2 1 
ATOM   351   N N   . HIS A 1 91  ? 117.714 137.811 126.474 1.00 62.16  ? 56  HIS A N   1 
ATOM   352   C CA  . HIS A 1 91  ? 118.953 138.565 126.637 1.00 55.40  ? 56  HIS A CA  1 
ATOM   353   C C   . HIS A 1 91  ? 119.323 139.312 125.363 1.00 47.24  ? 56  HIS A C   1 
ATOM   354   O O   . HIS A 1 91  ? 119.723 140.481 125.412 1.00 43.30  ? 56  HIS A O   1 
ATOM   355   C CB  . HIS A 1 91  ? 120.081 137.626 127.062 1.00 53.10  ? 56  HIS A CB  1 
ATOM   356   C CG  . HIS A 1 91  ? 119.873 137.009 128.410 1.00 65.81  ? 56  HIS A CG  1 
ATOM   357   N ND1 . HIS A 1 91  ? 120.534 137.445 129.538 1.00 71.68  ? 56  HIS A ND1 1 
ATOM   358   C CD2 . HIS A 1 91  ? 119.070 135.996 128.813 1.00 65.82  ? 56  HIS A CD2 1 
ATOM   359   C CE1 . HIS A 1 91  ? 120.151 136.724 130.576 1.00 68.66  ? 56  HIS A CE1 1 
ATOM   360   N NE2 . HIS A 1 91  ? 119.262 135.838 130.164 1.00 69.82  ? 56  HIS A NE2 1 
ATOM   361   N N   . ASP A 1 92  ? 119.194 138.656 124.213 1.00 44.36  ? 57  ASP A N   1 
ATOM   362   C CA  . ASP A 1 92  ? 119.535 139.258 122.934 1.00 44.11  ? 57  ASP A CA  1 
ATOM   363   C C   . ASP A 1 92  ? 118.358 139.957 122.270 1.00 45.64  ? 57  ASP A C   1 
ATOM   364   O O   . ASP A 1 92  ? 118.562 140.652 121.269 1.00 42.75  ? 57  ASP A O   1 
ATOM   365   C CB  . ASP A 1 92  ? 120.093 138.199 121.979 1.00 42.12  ? 57  ASP A CB  1 
ATOM   366   C CG  . ASP A 1 92  ? 121.331 137.520 122.521 1.00 44.98  ? 57  ASP A CG  1 
ATOM   367   O OD1 . ASP A 1 92  ? 122.125 138.194 123.209 1.00 45.13  ? 57  ASP A OD1 1 
ATOM   368   O OD2 . ASP A 1 92  ? 121.513 136.313 122.255 1.00 44.49  ? 57  ASP A OD2 1 
ATOM   369   N N   . MET A 1 93  ? 117.146 139.802 122.807 1.00 47.42  ? 58  MET A N   1 
ATOM   370   C CA  . MET A 1 93  ? 115.939 140.382 122.221 1.00 43.10  ? 58  MET A CA  1 
ATOM   371   C C   . MET A 1 93  ? 115.823 139.987 120.752 1.00 40.71  ? 58  MET A C   1 
ATOM   372   O O   . MET A 1 93  ? 115.678 140.823 119.858 1.00 38.88  ? 58  MET A O   1 
ATOM   373   C CB  . MET A 1 93  ? 115.917 141.901 122.394 1.00 42.68  ? 58  MET A CB  1 
ATOM   374   C CG  . MET A 1 93  ? 115.787 142.354 123.838 1.00 46.73  ? 58  MET A CG  1 
ATOM   375   S SD  . MET A 1 93  ? 115.357 144.096 123.990 1.00 72.90  ? 58  MET A SD  1 
ATOM   376   C CE  . MET A 1 93  ? 115.250 144.257 125.769 1.00 56.38  ? 58  MET A CE  1 
ATOM   377   N N   . GLU A 1 94  ? 115.888 138.679 120.516 1.00 39.37  ? 59  GLU A N   1 
ATOM   378   C CA  . GLU A 1 94  ? 115.821 138.115 119.180 1.00 30.95  ? 59  GLU A CA  1 
ATOM   379   C C   . GLU A 1 94  ? 115.167 136.747 119.268 1.00 31.08  ? 59  GLU A C   1 
ATOM   380   O O   . GLU A 1 94  ? 115.105 136.135 120.337 1.00 35.33  ? 59  GLU A O   1 
ATOM   381   C CB  . GLU A 1 94  ? 117.208 137.964 118.548 1.00 33.42  ? 59  GLU A CB  1 
ATOM   382   C CG  . GLU A 1 94  ? 118.054 136.898 119.236 1.00 38.69  ? 59  GLU A CG  1 
ATOM   383   C CD  . GLU A 1 94  ? 119.503 136.902 118.797 1.00 41.99  ? 59  GLU A CD  1 
ATOM   384   O OE1 . GLU A 1 94  ? 119.943 137.897 118.189 1.00 41.58  ? 59  GLU A OE1 1 
ATOM   385   O OE2 . GLU A 1 94  ? 120.203 135.902 119.059 1.00 41.42  ? 59  GLU A OE2 1 
ATOM   386   N N   . TYR A 1 95  ? 114.674 136.274 118.128 1.00 27.80  ? 60  TYR A N   1 
ATOM   387   C CA  . TYR A 1 95  ? 114.082 134.950 118.049 1.00 25.78  ? 60  TYR A CA  1 
ATOM   388   C C   . TYR A 1 95  ? 114.522 134.291 116.754 1.00 20.80  ? 60  TYR A C   1 
ATOM   389   O O   . TYR A 1 95  ? 114.838 134.965 115.771 1.00 23.87  ? 60  TYR A O   1 
ATOM   390   C CB  . TYR A 1 95  ? 112.550 135.002 118.134 1.00 24.84  ? 60  TYR A CB  1 
ATOM   391   C CG  . TYR A 1 95  ? 111.871 135.666 116.960 1.00 22.83  ? 60  TYR A CG  1 
ATOM   392   C CD1 . TYR A 1 95  ? 111.734 137.044 116.901 1.00 24.01  ? 60  TYR A CD1 1 
ATOM   393   C CD2 . TYR A 1 95  ? 111.350 134.912 115.921 1.00 23.22  ? 60  TYR A CD2 1 
ATOM   394   C CE1 . TYR A 1 95  ? 111.109 137.651 115.833 1.00 25.04  ? 60  TYR A CE1 1 
ATOM   395   C CE2 . TYR A 1 95  ? 110.724 135.511 114.850 1.00 22.47  ? 60  TYR A CE2 1 
ATOM   396   C CZ  . TYR A 1 95  ? 110.606 136.879 114.812 1.00 23.15  ? 60  TYR A CZ  1 
ATOM   397   O OH  . TYR A 1 95  ? 109.980 137.478 113.745 1.00 25.01  ? 60  TYR A OH  1 
ATOM   398   N N   . THR A 1 96  ? 114.548 132.965 116.767 1.00 18.31  ? 61  THR A N   1 
ATOM   399   C CA  . THR A 1 96  ? 114.890 132.175 115.597 1.00 15.80  ? 61  THR A CA  1 
ATOM   400   C C   . THR A 1 96  ? 113.623 131.591 114.985 1.00 16.02  ? 61  THR A C   1 
ATOM   401   O O   . THR A 1 96  ? 112.648 131.310 115.685 1.00 21.75  ? 61  THR A O   1 
ATOM   402   C CB  . THR A 1 96  ? 115.863 131.055 115.974 1.00 21.44  ? 61  THR A CB  1 
ATOM   403   O OG1 . THR A 1 96  ? 116.984 131.616 116.668 1.00 26.43  ? 61  THR A OG1 1 
ATOM   404   C CG2 . THR A 1 96  ? 116.368 130.334 114.740 1.00 19.82  ? 61  THR A CG2 1 
ATOM   405   N N   . ILE A 1 97  ? 113.636 131.430 113.667 1.00 14.87  ? 62  ILE A N   1 
ATOM   406   C CA  . ILE A 1 97  ? 112.481 130.903 112.950 1.00 17.38  ? 62  ILE A CA  1 
ATOM   407   C C   . ILE A 1 97  ? 112.972 130.191 111.695 1.00 16.21  ? 62  ILE A C   1 
ATOM   408   O O   . ILE A 1 97  ? 113.745 130.751 110.912 1.00 18.16  ? 62  ILE A O   1 
ATOM   409   C CB  . ILE A 1 97  ? 111.451 132.012 112.632 1.00 16.15  ? 62  ILE A CB  1 
ATOM   410   C CG1 . ILE A 1 97  ? 110.131 131.406 112.159 1.00 16.12  ? 62  ILE A CG1 1 
ATOM   411   C CG2 . ILE A 1 97  ? 111.989 133.038 111.639 1.00 13.80  ? 62  ILE A CG2 1 
ATOM   412   C CD1 . ILE A 1 97  ? 109.036 132.422 111.974 1.00 16.99  ? 62  ILE A CD1 1 
ATOM   413   N N   . ASP A 1 98  ? 112.566 128.936 111.530 1.00 13.75  ? 63  ASP A N   1 
ATOM   414   C CA  . ASP A 1 98  ? 112.889 128.172 110.334 1.00 11.80  ? 63  ASP A CA  1 
ATOM   415   C C   . ASP A 1 98  ? 111.659 128.174 109.440 1.00 12.34  ? 63  ASP A C   1 
ATOM   416   O O   . ASP A 1 98  ? 110.573 127.777 109.873 1.00 17.26  ? 63  ASP A O   1 
ATOM   417   C CB  . ASP A 1 98  ? 113.301 126.744 110.684 1.00 17.48  ? 63  ASP A CB  1 
ATOM   418   C CG  . ASP A 1 98  ? 114.708 126.661 111.244 1.00 25.62  ? 63  ASP A CG  1 
ATOM   419   O OD1 . ASP A 1 98  ? 114.919 127.097 112.395 1.00 25.60  ? 63  ASP A OD1 1 
ATOM   420   O OD2 . ASP A 1 98  ? 115.602 126.152 110.535 1.00 29.72  ? 63  ASP A OD2 1 
ATOM   421   N N   . VAL A 1 99  ? 111.830 128.618 108.195 1.00 10.23  ? 64  VAL A N   1 
ATOM   422   C CA  . VAL A 1 99  ? 110.712 128.857 107.294 1.00 10.05  ? 64  VAL A CA  1 
ATOM   423   C C   . VAL A 1 99  ? 111.034 128.326 105.906 1.00 10.84  ? 64  VAL A C   1 
ATOM   424   O O   . VAL A 1 99  ? 112.196 128.184 105.520 1.00 17.35  ? 64  VAL A O   1 
ATOM   425   C CB  . VAL A 1 99  ? 110.352 130.358 107.202 1.00 10.27  ? 64  VAL A CB  1 
ATOM   426   C CG1 . VAL A 1 99  ? 109.990 130.912 108.567 1.00 12.87  ? 64  VAL A CG1 1 
ATOM   427   C CG2 . VAL A 1 99  ? 111.500 131.146 106.593 1.00 10.64  ? 64  VAL A CG2 1 
ATOM   428   N N   . PHE A 1 100 ? 109.978 128.018 105.161 1.00 9.82   ? 65  PHE A N   1 
ATOM   429   C CA  . PHE A 1 100 ? 110.050 127.883 103.709 1.00 12.77  ? 65  PHE A CA  1 
ATOM   430   C C   . PHE A 1 100 ? 109.455 129.163 103.134 1.00 14.75  ? 65  PHE A C   1 
ATOM   431   O O   . PHE A 1 100 ? 108.234 129.312 103.052 1.00 16.34  ? 65  PHE A O   1 
ATOM   432   C CB  . PHE A 1 100 ? 109.316 126.642 103.214 1.00 14.19  ? 65  PHE A CB  1 
ATOM   433   C CG  . PHE A 1 100 ? 110.089 125.369 103.393 1.00 16.09  ? 65  PHE A CG  1 
ATOM   434   C CD1 . PHE A 1 100 ? 111.014 124.972 102.445 1.00 15.79  ? 65  PHE A CD1 1 
ATOM   435   C CD2 . PHE A 1 100 ? 109.891 124.568 104.500 1.00 22.30  ? 65  PHE A CD2 1 
ATOM   436   C CE1 . PHE A 1 100 ? 111.728 123.802 102.602 1.00 18.69  ? 65  PHE A CE1 1 
ATOM   437   C CE2 . PHE A 1 100 ? 110.603 123.395 104.661 1.00 19.05  ? 65  PHE A CE2 1 
ATOM   438   C CZ  . PHE A 1 100 ? 111.522 123.012 103.711 1.00 18.93  ? 65  PHE A CZ  1 
ATOM   439   N N   . PHE A 1 101 ? 110.323 130.082 102.730 1.00 14.30  ? 66  PHE A N   1 
ATOM   440   C CA  . PHE A 1 101 ? 109.895 131.374 102.220 1.00 14.07  ? 66  PHE A CA  1 
ATOM   441   C C   . PHE A 1 101 ? 109.571 131.251 100.740 1.00 14.63  ? 66  PHE A C   1 
ATOM   442   O O   . PHE A 1 101 ? 110.474 131.137 99.907  1.00 17.66  ? 66  PHE A O   1 
ATOM   443   C CB  . PHE A 1 101 ? 110.983 132.424 102.445 1.00 15.22  ? 66  PHE A CB  1 
ATOM   444   C CG  . PHE A 1 101 ? 110.528 133.831 102.203 1.00 12.07  ? 66  PHE A CG  1 
ATOM   445   C CD1 . PHE A 1 101 ? 109.571 134.412 103.014 1.00 13.20  ? 66  PHE A CD1 1 
ATOM   446   C CD2 . PHE A 1 101 ? 111.062 134.575 101.168 1.00 11.01  ? 66  PHE A CD2 1 
ATOM   447   C CE1 . PHE A 1 101 ? 109.151 135.705 102.792 1.00 14.68  ? 66  PHE A CE1 1 
ATOM   448   C CE2 . PHE A 1 101 ? 110.648 135.868 100.945 1.00 12.39  ? 66  PHE A CE2 1 
ATOM   449   C CZ  . PHE A 1 101 ? 109.691 136.434 101.756 1.00 14.95  ? 66  PHE A CZ  1 
ATOM   450   N N   . ARG A 1 102 ? 108.280 131.272 100.419 1.00 12.33  ? 67  ARG A N   1 
ATOM   451   C CA  . ARG A 1 102 ? 107.803 131.079 99.057  1.00 14.61  ? 67  ARG A CA  1 
ATOM   452   C C   . ARG A 1 102 ? 107.431 132.430 98.469  1.00 15.00  ? 67  ARG A C   1 
ATOM   453   O O   . ARG A 1 102 ? 106.616 133.158 99.043  1.00 20.10  ? 67  ARG A O   1 
ATOM   454   C CB  . ARG A 1 102 ? 106.606 130.127 99.025  1.00 15.70  ? 67  ARG A CB  1 
ATOM   455   C CG  . ARG A 1 102 ? 106.903 128.758 99.609  1.00 17.96  ? 67  ARG A CG  1 
ATOM   456   C CD  . ARG A 1 102 ? 105.647 127.922 99.761  1.00 20.35  ? 67  ARG A CD  1 
ATOM   457   N NE  . ARG A 1 102 ? 105.916 126.683 100.479 1.00 23.18  ? 67  ARG A NE  1 
ATOM   458   C CZ  . ARG A 1 102 ? 104.984 125.836 100.891 1.00 31.57  ? 67  ARG A CZ  1 
ATOM   459   N NH1 . ARG A 1 102 ? 103.699 126.062 100.671 1.00 33.71  ? 67  ARG A NH1 1 
ATOM   460   N NH2 . ARG A 1 102 ? 105.348 124.736 101.543 1.00 38.27  ? 67  ARG A NH2 1 
ATOM   461   N N   . GLN A 1 103 ? 108.026 132.757 97.329  1.00 16.29  ? 68  GLN A N   1 
ATOM   462   C CA  . GLN A 1 103 ? 107.748 133.986 96.605  1.00 17.17  ? 68  GLN A CA  1 
ATOM   463   C C   . GLN A 1 103 ? 107.199 133.640 95.232  1.00 20.32  ? 68  GLN A C   1 
ATOM   464   O O   . GLN A 1 103 ? 107.680 132.708 94.580  1.00 28.22  ? 68  GLN A O   1 
ATOM   465   C CB  . GLN A 1 103 ? 109.002 134.847 96.445  1.00 18.90  ? 68  GLN A CB  1 
ATOM   466   C CG  . GLN A 1 103 ? 109.536 135.432 97.729  1.00 19.52  ? 68  GLN A CG  1 
ATOM   467   C CD  . GLN A 1 103 ? 110.801 136.235 97.514  1.00 22.39  ? 68  GLN A CD  1 
ATOM   468   O OE1 . GLN A 1 103 ? 110.753 137.450 97.326  1.00 23.87  ? 68  GLN A OE1 1 
ATOM   469   N NE2 . GLN A 1 103 ? 111.942 135.558 97.531  1.00 22.50  ? 68  GLN A NE2 1 
ATOM   470   N N   . SER A 1 104 ? 106.190 134.382 94.796  1.00 17.35  ? 69  SER A N   1 
ATOM   471   C CA  . SER A 1 104 ? 105.609 134.166 93.483  1.00 19.53  ? 69  SER A CA  1 
ATOM   472   C C   . SER A 1 104 ? 105.408 135.506 92.798  1.00 21.85  ? 69  SER A C   1 
ATOM   473   O O   . SER A 1 104 ? 105.014 136.487 93.434  1.00 26.30  ? 69  SER A O   1 
ATOM   474   C CB  . SER A 1 104 ? 104.275 133.418 93.576  1.00 17.79  ? 69  SER A CB  1 
ATOM   475   O OG  . SER A 1 104 ? 103.791 133.076 92.290  1.00 15.92  ? 69  SER A OG  1 
ATOM   476   N N   . TRP A 1 105 ? 105.688 135.536 91.501  1.00 23.06  ? 70  TRP A N   1 
ATOM   477   C CA  . TRP A 1 105 ? 105.507 136.724 90.679  1.00 23.95  ? 70  TRP A CA  1 
ATOM   478   C C   . TRP A 1 105 ? 105.421 136.273 89.229  1.00 27.67  ? 70  TRP A C   1 
ATOM   479   O O   . TRP A 1 105 ? 105.530 135.083 88.923  1.00 34.16  ? 70  TRP A O   1 
ATOM   480   C CB  . TRP A 1 105 ? 106.637 137.737 90.887  1.00 29.44  ? 70  TRP A CB  1 
ATOM   481   C CG  . TRP A 1 105 ? 107.977 137.285 90.386  1.00 28.19  ? 70  TRP A CG  1 
ATOM   482   C CD1 . TRP A 1 105 ? 108.588 137.669 89.229  1.00 30.22  ? 70  TRP A CD1 1 
ATOM   483   C CD2 . TRP A 1 105 ? 108.897 136.410 91.052  1.00 25.65  ? 70  TRP A CD2 1 
ATOM   484   N NE1 . TRP A 1 105 ? 109.816 137.063 89.118  1.00 27.61  ? 70  TRP A NE1 1 
ATOM   485   C CE2 . TRP A 1 105 ? 110.030 136.289 90.227  1.00 27.21  ? 70  TRP A CE2 1 
ATOM   486   C CE3 . TRP A 1 105 ? 108.866 135.709 92.260  1.00 26.18  ? 70  TRP A CE3 1 
ATOM   487   C CZ2 . TRP A 1 105 ? 111.121 135.494 90.569  1.00 31.66  ? 70  TRP A CZ2 1 
ATOM   488   C CZ3 . TRP A 1 105 ? 109.952 134.920 92.598  1.00 27.11  ? 70  TRP A CZ3 1 
ATOM   489   C CH2 . TRP A 1 105 ? 111.061 134.818 91.755  1.00 30.62  ? 70  TRP A CH2 1 
ATOM   490   N N   . LYS A 1 106 ? 105.231 137.233 88.332  1.00 30.46  ? 71  LYS A N   1 
ATOM   491   C CA  . LYS A 1 106 ? 105.073 136.941 86.917  1.00 39.61  ? 71  LYS A CA  1 
ATOM   492   C C   . LYS A 1 106 ? 106.154 137.665 86.128  1.00 41.02  ? 71  LYS A C   1 
ATOM   493   O O   . LYS A 1 106 ? 106.448 138.836 86.386  1.00 40.41  ? 71  LYS A O   1 
ATOM   494   C CB  . LYS A 1 106 ? 103.685 137.354 86.417  1.00 42.81  ? 71  LYS A CB  1 
ATOM   495   C CG  . LYS A 1 106 ? 103.307 136.743 85.077  1.00 42.98  ? 71  LYS A CG  1 
ATOM   496   C CD  . LYS A 1 106 ? 101.834 136.947 84.767  1.00 44.71  ? 71  LYS A CD  1 
ATOM   497   C CE  . LYS A 1 106 ? 101.429 136.184 83.516  1.00 48.58  ? 71  LYS A CE  1 
ATOM   498   N NZ  . LYS A 1 106 ? 100.006 136.420 83.149  1.00 50.58  ? 71  LYS A NZ  1 
ATOM   499   N N   . ASP A 1 107 ? 106.742 136.957 85.167  1.00 44.98  ? 72  ASP A N   1 
ATOM   500   C CA  . ASP A 1 107 ? 107.742 137.523 84.267  1.00 42.36  ? 72  ASP A CA  1 
ATOM   501   C C   . ASP A 1 107 ? 107.398 137.056 82.861  1.00 52.10  ? 72  ASP A C   1 
ATOM   502   O O   . ASP A 1 107 ? 107.592 135.880 82.536  1.00 54.58  ? 72  ASP A O   1 
ATOM   503   C CB  . ASP A 1 107 ? 109.155 137.093 84.660  1.00 42.84  ? 72  ASP A CB  1 
ATOM   504   C CG  . ASP A 1 107 ? 110.231 137.854 83.906  1.00 46.18  ? 72  ASP A CG  1 
ATOM   505   O OD1 . ASP A 1 107 ? 109.890 138.630 82.988  1.00 51.93  ? 72  ASP A OD1 1 
ATOM   506   O OD2 . ASP A 1 107 ? 111.423 137.675 84.230  1.00 45.51  ? 72  ASP A OD2 1 
ATOM   507   N N   . GLU A 1 108 ? 106.886 137.968 82.032  1.00 56.67  ? 73  GLU A N   1 
ATOM   508   C CA  . GLU A 1 108 ? 106.452 137.580 80.694  1.00 65.27  ? 73  GLU A CA  1 
ATOM   509   C C   . GLU A 1 108 ? 107.622 137.112 79.840  1.00 63.68  ? 73  GLU A C   1 
ATOM   510   O O   . GLU A 1 108 ? 107.432 136.336 78.898  1.00 65.08  ? 73  GLU A O   1 
ATOM   511   C CB  . GLU A 1 108 ? 105.737 138.750 80.019  1.00 71.50  ? 73  GLU A CB  1 
ATOM   512   C CG  . GLU A 1 108 ? 104.479 139.205 80.736  1.00 75.81  ? 73  GLU A CG  1 
ATOM   513   C CD  . GLU A 1 108 ? 103.855 140.425 80.092  1.00 84.26  ? 73  GLU A CD  1 
ATOM   514   O OE1 . GLU A 1 108 ? 104.440 140.947 79.120  1.00 95.28  ? 73  GLU A OE1 1 
ATOM   515   O OE2 . GLU A 1 108 ? 102.781 140.863 80.556  1.00 77.39  ? 73  GLU A OE2 1 
ATOM   516   N N   . ARG A 1 109 ? 108.834 137.575 80.149  1.00 61.10  ? 74  ARG A N   1 
ATOM   517   C CA  . ARG A 1 109 ? 110.017 137.201 79.387  1.00 57.02  ? 74  ARG A CA  1 
ATOM   518   C C   . ARG A 1 109 ? 110.359 135.721 79.502  1.00 58.26  ? 74  ARG A C   1 
ATOM   519   O O   . ARG A 1 109 ? 111.169 135.230 78.709  1.00 61.36  ? 74  ARG A O   1 
ATOM   520   C CB  . ARG A 1 109 ? 111.208 138.031 79.863  1.00 58.01  ? 74  ARG A CB  1 
ATOM   521   C CG  . ARG A 1 109 ? 110.993 139.532 79.789  1.00 54.22  ? 74  ARG A CG  1 
ATOM   522   C CD  . ARG A 1 109 ? 112.148 140.277 80.437  1.00 51.86  ? 74  ARG A CD  1 
ATOM   523   N NE  . ARG A 1 109 ? 112.190 140.033 81.874  1.00 48.86  ? 74  ARG A NE  1 
ATOM   524   C CZ  . ARG A 1 109 ? 113.071 140.572 82.706  1.00 48.73  ? 74  ARG A CZ  1 
ATOM   525   N NH1 . ARG A 1 109 ? 114.013 141.396 82.277  1.00 53.93  ? 74  ARG A NH1 1 
ATOM   526   N NH2 . ARG A 1 109 ? 113.005 140.278 84.001  1.00 45.01  ? 74  ARG A NH2 1 
ATOM   527   N N   . LEU A 1 110 ? 109.770 135.002 80.460  1.00 61.95  ? 75  LEU A N   1 
ATOM   528   C CA  . LEU A 1 110 ? 110.100 133.603 80.701  1.00 69.72  ? 75  LEU A CA  1 
ATOM   529   C C   . LEU A 1 110 ? 108.978 132.649 80.299  1.00 71.32  ? 75  LEU A C   1 
ATOM   530   O O   . LEU A 1 110 ? 108.953 131.504 80.763  1.00 67.66  ? 75  LEU A O   1 
ATOM   531   C CB  . LEU A 1 110 ? 110.463 133.396 82.172  1.00 59.27  ? 75  LEU A CB  1 
ATOM   532   C CG  . LEU A 1 110 ? 111.717 134.119 82.669  1.00 55.50  ? 75  LEU A CG  1 
ATOM   533   C CD1 . LEU A 1 110 ? 111.911 133.903 84.163  1.00 42.86  ? 75  LEU A CD1 1 
ATOM   534   C CD2 . LEU A 1 110 ? 112.947 133.676 81.892  1.00 66.69  ? 75  LEU A CD2 1 
ATOM   535   N N   . LYS A 1 111 ? 108.043 133.093 79.463  1.00 74.43  ? 76  LYS A N   1 
ATOM   536   C CA  . LYS A 1 111 ? 107.049 132.173 78.928  1.00 80.09  ? 76  LYS A CA  1 
ATOM   537   C C   . LYS A 1 111 ? 107.712 131.104 78.066  1.00 85.37  ? 76  LYS A C   1 
ATOM   538   O O   . LYS A 1 111 ? 108.712 131.353 77.387  1.00 79.90  ? 76  LYS A O   1 
ATOM   539   C CB  . LYS A 1 111 ? 106.004 132.933 78.110  1.00 72.97  ? 76  LYS A CB  1 
ATOM   540   C CG  . LYS A 1 111 ? 105.136 133.870 78.932  1.00 68.12  ? 76  LYS A CG  1 
ATOM   541   C CD  . LYS A 1 111 ? 104.151 134.628 78.057  1.00 63.81  ? 76  LYS A CD  1 
ATOM   542   C CE  . LYS A 1 111 ? 103.238 135.509 78.896  1.00 64.63  ? 76  LYS A CE  1 
ATOM   543   N NZ  . LYS A 1 111 ? 102.246 136.245 78.063  1.00 64.51  ? 76  LYS A NZ  1 
ATOM   544   N N   . PHE A 1 112 ? 107.141 129.902 78.094  1.00 85.86  ? 77  PHE A N   1 
ATOM   545   C CA  . PHE A 1 112 ? 107.659 128.805 77.291  1.00 84.75  ? 77  PHE A CA  1 
ATOM   546   C C   . PHE A 1 112 ? 106.511 127.886 76.903  1.00 88.40  ? 77  PHE A C   1 
ATOM   547   O O   . PHE A 1 112 ? 105.443 127.897 77.521  1.00 87.40  ? 77  PHE A O   1 
ATOM   548   C CB  . PHE A 1 112 ? 108.763 128.032 78.030  1.00 82.73  ? 77  PHE A CB  1 
ATOM   549   C CG  . PHE A 1 112 ? 108.278 127.252 79.222  1.00 83.15  ? 77  PHE A CG  1 
ATOM   550   C CD1 . PHE A 1 112 ? 107.798 125.959 79.080  1.00 84.79  ? 77  PHE A CD1 1 
ATOM   551   C CD2 . PHE A 1 112 ? 108.320 127.807 80.490  1.00 80.22  ? 77  PHE A CD2 1 
ATOM   552   C CE1 . PHE A 1 112 ? 107.358 125.244 80.176  1.00 81.63  ? 77  PHE A CE1 1 
ATOM   553   C CE2 . PHE A 1 112 ? 107.884 127.094 81.590  1.00 76.67  ? 77  PHE A CE2 1 
ATOM   554   C CZ  . PHE A 1 112 ? 107.402 125.812 81.433  1.00 76.06  ? 77  PHE A CZ  1 
ATOM   555   N N   . LYS A 1 113 ? 106.746 127.087 75.866  1.00 93.88  ? 78  LYS A N   1 
ATOM   556   C CA  . LYS A 1 113 ? 105.791 126.093 75.400  1.00 100.09 ? 78  LYS A CA  1 
ATOM   557   C C   . LYS A 1 113 ? 106.497 124.757 75.231  1.00 95.96  ? 78  LYS A C   1 
ATOM   558   O O   . LYS A 1 113 ? 107.598 124.694 74.675  1.00 90.68  ? 78  LYS A O   1 
ATOM   559   C CB  . LYS A 1 113 ? 105.127 126.521 74.085  1.00 102.16 ? 78  LYS A CB  1 
ATOM   560   C CG  . LYS A 1 113 ? 104.437 127.875 74.163  1.00 100.39 ? 78  LYS A CG  1 
ATOM   561   C CD  . LYS A 1 113 ? 103.895 128.315 72.814  1.00 107.41 ? 78  LYS A CD  1 
ATOM   562   C CE  . LYS A 1 113 ? 103.245 129.687 72.910  1.00 115.34 ? 78  LYS A CE  1 
ATOM   563   N NZ  . LYS A 1 113 ? 102.689 130.137 71.605  1.00 120.02 ? 78  LYS A NZ  1 
ATOM   564   N N   . GLY A 1 114 ? 105.859 123.691 75.708  1.00 93.03  ? 79  GLY A N   1 
ATOM   565   C CA  . GLY A 1 114 ? 106.426 122.368 75.613  1.00 92.25  ? 79  GLY A CA  1 
ATOM   566   C C   . GLY A 1 114 ? 105.569 121.309 76.274  1.00 96.13  ? 79  GLY A C   1 
ATOM   567   O O   . GLY A 1 114 ? 104.469 121.582 76.765  1.00 100.20 ? 79  GLY A O   1 
ATOM   568   N N   . PRO A 1 115 ? 106.057 120.065 76.282  1.00 96.41  ? 80  PRO A N   1 
ATOM   569   C CA  . PRO A 1 115 ? 105.292 118.983 76.927  1.00 96.34  ? 80  PRO A CA  1 
ATOM   570   C C   . PRO A 1 115 ? 105.007 119.216 78.402  1.00 93.64  ? 80  PRO A C   1 
ATOM   571   O O   . PRO A 1 115 ? 103.923 118.857 78.878  1.00 91.67  ? 80  PRO A O   1 
ATOM   572   C CB  . PRO A 1 115 ? 106.182 117.750 76.711  1.00 90.09  ? 80  PRO A CB  1 
ATOM   573   C CG  . PRO A 1 115 ? 107.049 118.096 75.547  1.00 85.19  ? 80  PRO A CG  1 
ATOM   574   C CD  . PRO A 1 115 ? 107.286 119.572 75.636  1.00 88.88  ? 80  PRO A CD  1 
ATOM   575   N N   . MET A 1 116 ? 105.942 119.804 79.142  1.00 92.08  ? 81  MET A N   1 
ATOM   576   C CA  . MET A 1 116 ? 105.787 119.980 80.579  1.00 94.77  ? 81  MET A CA  1 
ATOM   577   C C   . MET A 1 116 ? 105.284 121.380 80.901  1.00 91.16  ? 81  MET A C   1 
ATOM   578   O O   . MET A 1 116 ? 105.641 122.352 80.229  1.00 90.31  ? 81  MET A O   1 
ATOM   579   C CB  . MET A 1 116 ? 107.110 119.726 81.304  1.00 95.04  ? 81  MET A CB  1 
ATOM   580   C CG  . MET A 1 116 ? 107.552 118.273 81.296  1.00 101.24 ? 81  MET A CG  1 
ATOM   581   S SD  . MET A 1 116 ? 109.011 117.982 82.315  1.00 120.26 ? 81  MET A SD  1 
ATOM   582   C CE  . MET A 1 116 ? 108.373 118.377 83.941  1.00 108.23 ? 81  MET A CE  1 
ATOM   583   N N   . THR A 1 117 ? 104.447 121.473 81.936  1.00 90.54  ? 82  THR A N   1 
ATOM   584   C CA  . THR A 1 117 ? 103.887 122.742 82.378  1.00 88.28  ? 82  THR A CA  1 
ATOM   585   C C   . THR A 1 117 ? 104.671 123.379 83.518  1.00 83.32  ? 82  THR A C   1 
ATOM   586   O O   . THR A 1 117 ? 104.364 124.513 83.899  1.00 74.29  ? 82  THR A O   1 
ATOM   587   C CB  . THR A 1 117 ? 102.428 122.558 82.816  1.00 82.10  ? 82  THR A CB  1 
ATOM   588   O OG1 . THR A 1 117 ? 102.370 121.658 83.929  1.00 82.03  ? 82  THR A OG1 1 
ATOM   589   C CG2 . THR A 1 117 ? 101.593 122.000 81.673  1.00 80.54  ? 82  THR A CG2 1 
ATOM   590   N N   . VAL A 1 118 ? 105.666 122.685 84.069  1.00 82.50  ? 83  VAL A N   1 
ATOM   591   C CA  . VAL A 1 118 ? 106.480 123.198 85.165  1.00 75.12  ? 83  VAL A CA  1 
ATOM   592   C C   . VAL A 1 118 ? 107.924 122.785 84.922  1.00 72.98  ? 83  VAL A C   1 
ATOM   593   O O   . VAL A 1 118 ? 108.197 121.644 84.534  1.00 72.54  ? 83  VAL A O   1 
ATOM   594   C CB  . VAL A 1 118 ? 105.999 122.680 86.540  1.00 70.64  ? 83  VAL A CB  1 
ATOM   595   C CG1 . VAL A 1 118 ? 106.812 123.308 87.662  1.00 66.55  ? 83  VAL A CG1 1 
ATOM   596   C CG2 . VAL A 1 118 ? 104.515 122.950 86.750  1.00 64.97  ? 83  VAL A CG2 1 
ATOM   597   N N   . LEU A 1 119 ? 108.848 123.717 85.143  1.00 70.03  ? 84  LEU A N   1 
ATOM   598   C CA  . LEU A 1 119 ? 110.276 123.466 85.000  1.00 67.84  ? 84  LEU A CA  1 
ATOM   599   C C   . LEU A 1 119 ? 110.944 123.688 86.347  1.00 59.83  ? 84  LEU A C   1 
ATOM   600   O O   . LEU A 1 119 ? 110.689 124.700 87.006  1.00 59.40  ? 84  LEU A O   1 
ATOM   601   C CB  . LEU A 1 119 ? 110.897 124.391 83.951  1.00 69.50  ? 84  LEU A CB  1 
ATOM   602   C CG  . LEU A 1 119 ? 110.464 124.208 82.497  1.00 77.68  ? 84  LEU A CG  1 
ATOM   603   C CD1 . LEU A 1 119 ? 111.070 125.298 81.632  1.00 81.81  ? 84  LEU A CD1 1 
ATOM   604   C CD2 . LEU A 1 119 ? 110.841 122.835 81.976  1.00 78.80  ? 84  LEU A CD2 1 
ATOM   605   N N   . ARG A 1 120 ? 111.797 122.754 86.757  1.00 64.93  ? 85  ARG A N   1 
ATOM   606   C CA  . ARG A 1 120 ? 112.607 122.923 87.958  1.00 69.18  ? 85  ARG A CA  1 
ATOM   607   C C   . ARG A 1 120 ? 113.990 123.429 87.559  1.00 70.33  ? 85  ARG A C   1 
ATOM   608   O O   . ARG A 1 120 ? 114.801 122.675 87.012  1.00 67.39  ? 85  ARG A O   1 
ATOM   609   C CB  . ARG A 1 120 ? 112.699 121.613 88.735  1.00 71.70  ? 85  ARG A CB  1 
ATOM   610   C CG  . ARG A 1 120 ? 111.397 121.216 89.406  1.00 75.70  ? 85  ARG A CG  1 
ATOM   611   C CD  . ARG A 1 120 ? 111.476 119.823 90.002  1.00 83.57  ? 85  ARG A CD  1 
ATOM   612   N NE  . ARG A 1 120 ? 110.201 119.413 90.577  1.00 89.73  ? 85  ARG A NE  1 
ATOM   613   C CZ  . ARG A 1 120 ? 109.199 118.890 89.884  1.00 88.43  ? 85  ARG A CZ  1 
ATOM   614   N NH1 . ARG A 1 120 ? 109.293 118.688 88.580  1.00 92.68  ? 85  ARG A NH1 1 
ATOM   615   N NH2 . ARG A 1 120 ? 108.075 118.561 90.514  1.00 80.74  ? 85  ARG A NH2 1 
ATOM   616   N N   . LEU A 1 121 ? 114.252 124.704 87.830  1.00 67.84  ? 86  LEU A N   1 
ATOM   617   C CA  . LEU A 1 121 ? 115.542 125.291 87.501  1.00 66.97  ? 86  LEU A CA  1 
ATOM   618   C C   . LEU A 1 121 ? 116.630 124.763 88.430  1.00 73.06  ? 86  LEU A C   1 
ATOM   619   O O   . LEU A 1 121 ? 116.376 124.400 89.582  1.00 63.84  ? 86  LEU A O   1 
ATOM   620   C CB  . LEU A 1 121 ? 115.478 126.815 87.580  1.00 67.40  ? 86  LEU A CB  1 
ATOM   621   C CG  . LEU A 1 121 ? 114.645 127.505 86.499  1.00 69.57  ? 86  LEU A CG  1 
ATOM   622   C CD1 . LEU A 1 121 ? 114.823 129.012 86.570  1.00 69.64  ? 86  LEU A CD1 1 
ATOM   623   C CD2 . LEU A 1 121 ? 115.012 126.984 85.120  1.00 69.77  ? 86  LEU A CD2 1 
ATOM   624   N N   . ASN A 1 122 ? 117.857 124.732 87.918  1.00 80.74  ? 87  ASN A N   1 
ATOM   625   C CA  . ASN A 1 122 ? 119.001 124.355 88.729  1.00 78.48  ? 87  ASN A CA  1 
ATOM   626   C C   . ASN A 1 122 ? 119.395 125.511 89.647  1.00 75.86  ? 87  ASN A C   1 
ATOM   627   O O   . ASN A 1 122 ? 118.961 126.653 89.473  1.00 77.40  ? 87  ASN A O   1 
ATOM   628   C CB  . ASN A 1 122 ? 120.175 123.952 87.837  1.00 74.20  ? 87  ASN A CB  1 
ATOM   629   C CG  . ASN A 1 122 ? 121.183 123.081 88.557  1.00 80.49  ? 87  ASN A CG  1 
ATOM   630   O OD1 . ASN A 1 122 ? 120.829 122.302 89.440  1.00 84.93  ? 87  ASN A OD1 1 
ATOM   631   N ND2 . ASN A 1 122 ? 122.451 123.211 88.184  1.00 81.47  ? 87  ASN A ND2 1 
ATOM   632   N N   . ASN A 1 123 ? 120.226 125.204 90.645  1.00 75.41  ? 88  ASN A N   1 
ATOM   633   C CA  . ASN A 1 123 ? 120.698 126.248 91.550  1.00 74.46  ? 88  ASN A CA  1 
ATOM   634   C C   . ASN A 1 123 ? 121.520 127.291 90.804  1.00 74.49  ? 88  ASN A C   1 
ATOM   635   O O   . ASN A 1 123 ? 121.425 128.490 91.088  1.00 73.38  ? 88  ASN A O   1 
ATOM   636   C CB  . ASN A 1 123 ? 121.512 125.630 92.685  1.00 75.30  ? 88  ASN A CB  1 
ATOM   637   C CG  . ASN A 1 123 ? 122.622 124.725 92.184  1.00 85.16  ? 88  ASN A CG  1 
ATOM   638   O OD1 . ASN A 1 123 ? 123.580 125.182 91.558  1.00 87.16  ? 88  ASN A OD1 1 
ATOM   639   N ND2 . ASN A 1 123 ? 122.499 123.430 92.459  1.00 83.17  ? 88  ASN A ND2 1 
ATOM   640   N N   . LEU A 1 124 ? 122.345 126.849 89.853  1.00 75.88  ? 89  LEU A N   1 
ATOM   641   C CA  . LEU A 1 124 ? 123.081 127.786 89.012  1.00 71.48  ? 89  LEU A CA  1 
ATOM   642   C C   . LEU A 1 124 ? 122.142 128.606 88.137  1.00 71.60  ? 89  LEU A C   1 
ATOM   643   O O   . LEU A 1 124 ? 122.325 129.819 87.983  1.00 74.34  ? 89  LEU A O   1 
ATOM   644   C CB  . LEU A 1 124 ? 124.093 127.034 88.148  1.00 66.01  ? 89  LEU A CB  1 
ATOM   645   C CG  . LEU A 1 124 ? 124.941 127.901 87.216  1.00 68.51  ? 89  LEU A CG  1 
ATOM   646   C CD1 . LEU A 1 124 ? 125.779 128.883 88.017  1.00 72.95  ? 89  LEU A CD1 1 
ATOM   647   C CD2 . LEU A 1 124 ? 125.821 127.039 86.325  1.00 66.19  ? 89  LEU A CD2 1 
ATOM   648   N N   . MET A 1 125 ? 121.127 127.959 87.557  1.00 69.65  ? 90  MET A N   1 
ATOM   649   C CA  . MET A 1 125 ? 120.157 128.676 86.735  1.00 68.55  ? 90  MET A CA  1 
ATOM   650   C C   . MET A 1 125 ? 119.386 129.715 87.538  1.00 65.69  ? 90  MET A C   1 
ATOM   651   O O   . MET A 1 125 ? 119.157 130.830 87.056  1.00 64.92  ? 90  MET A O   1 
ATOM   652   C CB  . MET A 1 125 ? 119.191 127.685 86.085  1.00 74.07  ? 90  MET A CB  1 
ATOM   653   C CG  . MET A 1 125 ? 119.814 126.832 84.996  1.00 87.04  ? 90  MET A CG  1 
ATOM   654   S SD  . MET A 1 125 ? 119.976 127.712 83.431  1.00 105.24 ? 90  MET A SD  1 
ATOM   655   C CE  . MET A 1 125 ? 118.255 127.914 82.977  1.00 87.10  ? 90  MET A CE  1 
ATOM   656   N N   . ALA A 1 126 ? 118.962 129.366 88.756  1.00 63.24  ? 91  ALA A N   1 
ATOM   657   C CA  . ALA A 1 126 ? 118.196 130.311 89.564  1.00 60.85  ? 91  ALA A CA  1 
ATOM   658   C C   . ALA A 1 126 ? 118.954 131.612 89.794  1.00 65.24  ? 91  ALA A C   1 
ATOM   659   O O   . ALA A 1 126 ? 118.337 132.679 89.887  1.00 65.94  ? 91  ALA A O   1 
ATOM   660   C CB  . ALA A 1 126 ? 117.821 129.674 90.902  1.00 59.97  ? 91  ALA A CB  1 
ATOM   661   N N   . SER A 1 127 ? 120.282 131.549 89.889  1.00 67.31  ? 92  SER A N   1 
ATOM   662   C CA  . SER A 1 127 ? 121.084 132.748 90.094  1.00 63.30  ? 92  SER A CA  1 
ATOM   663   C C   . SER A 1 127 ? 121.345 133.521 88.808  1.00 62.54  ? 92  SER A C   1 
ATOM   664   O O   . SER A 1 127 ? 121.896 134.624 88.873  1.00 61.50  ? 92  SER A O   1 
ATOM   665   C CB  . SER A 1 127 ? 122.417 132.385 90.751  1.00 58.62  ? 92  SER A CB  1 
ATOM   666   O OG  . SER A 1 127 ? 123.138 131.457 89.960  1.00 66.35  ? 92  SER A OG  1 
ATOM   667   N N   . LYS A 1 128 ? 120.966 132.978 87.652  1.00 65.56  ? 93  LYS A N   1 
ATOM   668   C CA  . LYS A 1 128 ? 121.174 133.651 86.377  1.00 64.08  ? 93  LYS A CA  1 
ATOM   669   C C   . LYS A 1 128 ? 120.006 134.535 85.960  1.00 61.68  ? 93  LYS A C   1 
ATOM   670   O O   . LYS A 1 128 ? 120.122 135.254 84.962  1.00 65.28  ? 93  LYS A O   1 
ATOM   671   C CB  . LYS A 1 128 ? 121.438 132.618 85.276  1.00 70.49  ? 93  LYS A CB  1 
ATOM   672   C CG  . LYS A 1 128 ? 122.676 131.766 85.505  1.00 72.55  ? 93  LYS A CG  1 
ATOM   673   C CD  . LYS A 1 128 ? 123.956 132.555 85.300  1.00 72.91  ? 93  LYS A CD  1 
ATOM   674   C CE  . LYS A 1 128 ? 125.175 131.659 85.448  1.00 74.76  ? 93  LYS A CE  1 
ATOM   675   N NZ  . LYS A 1 128 ? 126.445 132.402 85.228  1.00 87.95  ? 93  LYS A NZ  1 
ATOM   676   N N   . ILE A 1 129 ? 118.893 134.500 86.688  1.00 61.90  ? 94  ILE A N   1 
ATOM   677   C CA  . ILE A 1 129 ? 117.677 135.205 86.309  1.00 60.06  ? 94  ILE A CA  1 
ATOM   678   C C   . ILE A 1 129 ? 117.313 136.175 87.429  1.00 59.04  ? 94  ILE A C   1 
ATOM   679   O O   . ILE A 1 129 ? 117.849 136.111 88.535  1.00 56.59  ? 94  ILE A O   1 
ATOM   680   C CB  . ILE A 1 129 ? 116.508 134.249 85.993  1.00 53.72  ? 94  ILE A CB  1 
ATOM   681   C CG1 . ILE A 1 129 ? 115.672 133.970 87.239  1.00 47.29  ? 94  ILE A CG1 1 
ATOM   682   C CG2 . ILE A 1 129 ? 117.026 132.944 85.412  1.00 55.79  ? 94  ILE A CG2 1 
ATOM   683   C CD1 . ILE A 1 129 ? 114.611 132.934 87.008  1.00 44.20  ? 94  ILE A CD1 1 
ATOM   684   N N   . TRP A 1 130 ? 116.378 137.074 87.130  1.00 54.56  ? 95  TRP A N   1 
ATOM   685   C CA  . TRP A 1 130 ? 115.987 138.095 88.091  1.00 48.33  ? 95  TRP A CA  1 
ATOM   686   C C   . TRP A 1 130 ? 115.012 137.518 89.106  1.00 45.53  ? 95  TRP A C   1 
ATOM   687   O O   . TRP A 1 130 ? 114.008 136.898 88.741  1.00 45.27  ? 95  TRP A O   1 
ATOM   688   C CB  . TRP A 1 130 ? 115.348 139.290 87.384  1.00 44.28  ? 95  TRP A CB  1 
ATOM   689   C CG  . TRP A 1 130 ? 114.970 140.407 88.319  1.00 44.72  ? 95  TRP A CG  1 
ATOM   690   C CD1 . TRP A 1 130 ? 115.715 141.511 88.614  1.00 49.20  ? 95  TRP A CD1 1 
ATOM   691   C CD2 . TRP A 1 130 ? 113.764 140.522 89.087  1.00 44.84  ? 95  TRP A CD2 1 
ATOM   692   N NE1 . TRP A 1 130 ? 115.048 142.308 89.511  1.00 43.51  ? 95  TRP A NE1 1 
ATOM   693   C CE2 . TRP A 1 130 ? 113.849 141.723 89.819  1.00 43.56  ? 95  TRP A CE2 1 
ATOM   694   C CE3 . TRP A 1 130 ? 112.623 139.728 89.227  1.00 42.53  ? 95  TRP A CE3 1 
ATOM   695   C CZ2 . TRP A 1 130 ? 112.836 142.149 90.676  1.00 42.86  ? 95  TRP A CZ2 1 
ATOM   696   C CZ3 . TRP A 1 130 ? 111.618 140.153 90.080  1.00 42.29  ? 95  TRP A CZ3 1 
ATOM   697   C CH2 . TRP A 1 130 ? 111.732 141.352 90.792  1.00 41.53  ? 95  TRP A CH2 1 
ATOM   698   N N   . THR A 1 131 ? 115.313 137.734 90.380  1.00 40.97  ? 96  THR A N   1 
ATOM   699   C CA  . THR A 1 131 ? 114.463 137.381 91.502  1.00 36.90  ? 96  THR A CA  1 
ATOM   700   C C   . THR A 1 131 ? 114.307 138.600 92.396  1.00 39.82  ? 96  THR A C   1 
ATOM   701   O O   . THR A 1 131 ? 115.166 139.487 92.389  1.00 41.60  ? 96  THR A O   1 
ATOM   702   C CB  . THR A 1 131 ? 115.061 136.223 92.317  1.00 36.87  ? 96  THR A CB  1 
ATOM   703   O OG1 . THR A 1 131 ? 116.295 136.642 92.909  1.00 42.57  ? 96  THR A OG1 1 
ATOM   704   C CG2 . THR A 1 131 ? 115.313 135.017 91.431  1.00 42.57  ? 96  THR A CG2 1 
ATOM   705   N N   . PRO A 1 132 ? 113.218 138.681 93.162  1.00 37.04  ? 97  PRO A N   1 
ATOM   706   C CA  . PRO A 1 132 ? 113.029 139.842 94.037  1.00 32.49  ? 97  PRO A CA  1 
ATOM   707   C C   . PRO A 1 132 ? 114.164 139.941 95.041  1.00 34.68  ? 97  PRO A C   1 
ATOM   708   O O   . PRO A 1 132 ? 114.666 138.932 95.542  1.00 33.61  ? 97  PRO A O   1 
ATOM   709   C CB  . PRO A 1 132 ? 111.686 139.563 94.720  1.00 28.42  ? 97  PRO A CB  1 
ATOM   710   C CG  . PRO A 1 132 ? 111.000 138.594 93.832  1.00 29.70  ? 97  PRO A CG  1 
ATOM   711   C CD  . PRO A 1 132 ? 112.078 137.754 93.233  1.00 34.12  ? 97  PRO A CD  1 
ATOM   712   N N   . ASP A 1 133 ? 114.566 141.173 95.337  1.00 35.14  ? 98  ASP A N   1 
ATOM   713   C CA  . ASP A 1 133 ? 115.595 141.414 96.345  1.00 34.33  ? 98  ASP A CA  1 
ATOM   714   C C   . ASP A 1 133 ? 114.960 141.612 97.720  1.00 26.64  ? 98  ASP A C   1 
ATOM   715   O O   . ASP A 1 133 ? 115.121 142.629 98.393  1.00 23.71  ? 98  ASP A O   1 
ATOM   716   C CB  . ASP A 1 133 ? 116.448 142.610 95.940  1.00 38.39  ? 98  ASP A CB  1 
ATOM   717   C CG  . ASP A 1 133 ? 115.631 143.876 95.770  1.00 37.39  ? 98  ASP A CG  1 
ATOM   718   O OD1 . ASP A 1 133 ? 114.405 143.769 95.561  1.00 34.04  ? 98  ASP A OD1 1 
ATOM   719   O OD2 . ASP A 1 133 ? 116.215 144.977 95.838  1.00 38.59  ? 98  ASP A OD2 1 
ATOM   720   N N   . THR A 1 134 ? 114.229 140.580 98.128  1.00 23.46  ? 99  THR A N   1 
ATOM   721   C CA  . THR A 1 134 ? 113.573 140.577 99.425  1.00 20.11  ? 99  THR A CA  1 
ATOM   722   C C   . THR A 1 134 ? 114.606 140.444 100.535 1.00 19.59  ? 99  THR A C   1 
ATOM   723   O O   . THR A 1 134 ? 115.539 139.641 100.445 1.00 25.96  ? 99  THR A O   1 
ATOM   724   C CB  . THR A 1 134 ? 112.557 139.437 99.502  1.00 21.06  ? 99  THR A CB  1 
ATOM   725   O OG1 . THR A 1 134 ? 111.526 139.651 98.531  1.00 21.45  ? 99  THR A OG1 1 
ATOM   726   C CG2 . THR A 1 134 ? 111.927 139.364 100.883 1.00 16.52  ? 99  THR A CG2 1 
ATOM   727   N N   . PHE A 1 135 ? 114.433 141.233 101.589 1.00 17.00  ? 100 PHE A N   1 
ATOM   728   C CA  . PHE A 1 135 ? 115.260 141.137 102.779 1.00 13.27  ? 100 PHE A CA  1 
ATOM   729   C C   . PHE A 1 135 ? 114.340 141.280 103.977 1.00 14.21  ? 100 PHE A C   1 
ATOM   730   O O   . PHE A 1 135 ? 113.182 141.674 103.842 1.00 18.77  ? 100 PHE A O   1 
ATOM   731   C CB  . PHE A 1 135 ? 116.364 142.200 102.800 1.00 14.05  ? 100 PHE A CB  1 
ATOM   732   C CG  . PHE A 1 135 ? 115.903 143.549 103.272 1.00 14.16  ? 100 PHE A CG  1 
ATOM   733   C CD1 . PHE A 1 135 ? 115.047 144.315 102.503 1.00 15.29  ? 100 PHE A CD1 1 
ATOM   734   C CD2 . PHE A 1 135 ? 116.332 144.053 104.487 1.00 15.84  ? 100 PHE A CD2 1 
ATOM   735   C CE1 . PHE A 1 135 ? 114.627 145.554 102.939 1.00 15.33  ? 100 PHE A CE1 1 
ATOM   736   C CE2 . PHE A 1 135 ? 115.915 145.290 104.926 1.00 15.23  ? 100 PHE A CE2 1 
ATOM   737   C CZ  . PHE A 1 135 ? 115.063 146.042 104.151 1.00 15.12  ? 100 PHE A CZ  1 
ATOM   738   N N   . PHE A 1 136 ? 114.861 140.983 105.159 1.00 12.33  ? 101 PHE A N   1 
ATOM   739   C CA  . PHE A 1 136 ? 114.090 141.084 106.389 1.00 10.60  ? 101 PHE A CA  1 
ATOM   740   C C   . PHE A 1 136 ? 114.493 142.343 107.142 1.00 13.11  ? 101 PHE A C   1 
ATOM   741   O O   . PHE A 1 136 ? 115.672 142.535 107.453 1.00 16.40  ? 101 PHE A O   1 
ATOM   742   C CB  . PHE A 1 136 ? 114.288 139.839 107.253 1.00 9.89   ? 101 PHE A CB  1 
ATOM   743   C CG  . PHE A 1 136 ? 113.747 138.586 106.628 1.00 10.65  ? 101 PHE A CG  1 
ATOM   744   C CD1 . PHE A 1 136 ? 112.410 138.257 106.751 1.00 11.69  ? 101 PHE A CD1 1 
ATOM   745   C CD2 . PHE A 1 136 ? 114.571 137.747 105.900 1.00 10.48  ? 101 PHE A CD2 1 
ATOM   746   C CE1 . PHE A 1 136 ? 111.909 137.112 106.173 1.00 9.37   ? 101 PHE A CE1 1 
ATOM   747   C CE2 . PHE A 1 136 ? 114.073 136.600 105.318 1.00 8.59   ? 101 PHE A CE2 1 
ATOM   748   C CZ  . PHE A 1 136 ? 112.742 136.284 105.455 1.00 8.15   ? 101 PHE A CZ  1 
ATOM   749   N N   . HIS A 1 137 ? 113.508 143.201 107.420 1.00 14.29  ? 102 HIS A N   1 
ATOM   750   C CA  . HIS A 1 137 ? 113.799 144.518 107.976 1.00 14.29  ? 102 HIS A CA  1 
ATOM   751   C C   . HIS A 1 137 ? 114.423 144.404 109.359 1.00 15.80  ? 102 HIS A C   1 
ATOM   752   O O   . HIS A 1 137 ? 115.356 145.144 109.691 1.00 19.47  ? 102 HIS A O   1 
ATOM   753   C CB  . HIS A 1 137 ? 112.518 145.350 108.043 1.00 15.77  ? 102 HIS A CB  1 
ATOM   754   C CG  . HIS A 1 137 ? 111.996 145.770 106.705 1.00 21.47  ? 102 HIS A CG  1 
ATOM   755   N ND1 . HIS A 1 137 ? 111.588 147.059 106.438 1.00 25.43  ? 102 HIS A ND1 1 
ATOM   756   C CD2 . HIS A 1 137 ? 111.805 145.071 105.562 1.00 20.32  ? 102 HIS A CD2 1 
ATOM   757   C CE1 . HIS A 1 137 ? 111.175 147.137 105.186 1.00 23.67  ? 102 HIS A CE1 1 
ATOM   758   N NE2 . HIS A 1 137 ? 111.296 145.945 104.632 1.00 20.95  ? 102 HIS A NE2 1 
ATOM   759   N N   . ASN A 1 138 ? 113.915 143.491 110.184 1.00 14.18  ? 103 ASN A N   1 
ATOM   760   C CA  . ASN A 1 138 ? 114.421 143.297 111.533 1.00 15.29  ? 103 ASN A CA  1 
ATOM   761   C C   . ASN A 1 138 ? 115.329 142.080 111.652 1.00 19.51  ? 103 ASN A C   1 
ATOM   762   O O   . ASN A 1 138 ? 115.543 141.585 112.762 1.00 22.11  ? 103 ASN A O   1 
ATOM   763   C CB  . ASN A 1 138 ? 113.256 143.184 112.517 1.00 15.65  ? 103 ASN A CB  1 
ATOM   764   C CG  . ASN A 1 138 ? 112.308 142.059 112.167 1.00 17.78  ? 103 ASN A CG  1 
ATOM   765   O OD1 . ASN A 1 138 ? 111.938 141.883 111.009 1.00 19.71  ? 103 ASN A OD1 1 
ATOM   766   N ND2 . ASN A 1 138 ? 111.903 141.294 113.171 1.00 20.27  ? 103 ASN A ND2 1 
ATOM   767   N N   . GLY A 1 139 ? 115.864 141.580 110.540 1.00 20.09  ? 104 GLY A N   1 
ATOM   768   C CA  . GLY A 1 139 ? 116.778 140.458 110.618 1.00 16.17  ? 104 GLY A CA  1 
ATOM   769   C C   . GLY A 1 139 ? 118.116 140.852 111.214 1.00 16.13  ? 104 GLY A C   1 
ATOM   770   O O   . GLY A 1 139 ? 118.605 141.966 111.030 1.00 19.22  ? 104 GLY A O   1 
ATOM   771   N N   . LYS A 1 140 ? 118.714 139.916 111.948 1.00 17.39  ? 105 LYS A N   1 
ATOM   772   C CA  . LYS A 1 140 ? 120.008 140.128 112.583 1.00 19.51  ? 105 LYS A CA  1 
ATOM   773   C C   . LYS A 1 140 ? 121.131 139.358 111.907 1.00 21.34  ? 105 LYS A C   1 
ATOM   774   O O   . LYS A 1 140 ? 122.148 139.945 111.531 1.00 25.60  ? 105 LYS A O   1 
ATOM   775   C CB  . LYS A 1 140 ? 119.935 139.753 114.068 1.00 19.99  ? 105 LYS A CB  1 
ATOM   776   C CG  . LYS A 1 140 ? 119.031 140.668 114.871 1.00 22.64  ? 105 LYS A CG  1 
ATOM   777   C CD  . LYS A 1 140 ? 119.061 140.331 116.345 1.00 25.60  ? 105 LYS A CD  1 
ATOM   778   C CE  . LYS A 1 140 ? 120.382 140.735 116.970 1.00 28.08  ? 105 LYS A CE  1 
ATOM   779   N NZ  . LYS A 1 140 ? 120.350 140.580 118.451 1.00 29.71  ? 105 LYS A NZ  1 
ATOM   780   N N   . LYS A 1 141 ? 120.980 138.041 111.765 1.00 20.23  ? 106 LYS A N   1 
ATOM   781   C CA  . LYS A 1 141 ? 121.966 137.219 111.065 1.00 20.17  ? 106 LYS A CA  1 
ATOM   782   C C   . LYS A 1 141 ? 121.237 135.983 110.549 1.00 19.61  ? 106 LYS A C   1 
ATOM   783   O O   . LYS A 1 141 ? 121.053 135.015 111.293 1.00 23.27  ? 106 LYS A O   1 
ATOM   784   C CB  . LYS A 1 141 ? 123.122 136.847 111.983 1.00 23.57  ? 106 LYS A CB  1 
ATOM   785   C CG  . LYS A 1 141 ? 124.211 136.021 111.321 1.00 29.19  ? 106 LYS A CG  1 
ATOM   786   C CD  . LYS A 1 141 ? 124.927 136.802 110.234 1.00 30.21  ? 106 LYS A CD  1 
ATOM   787   C CE  . LYS A 1 141 ? 126.126 136.030 109.709 1.00 29.31  ? 106 LYS A CE  1 
ATOM   788   N NZ  . LYS A 1 141 ? 126.876 136.794 108.676 1.00 30.96  ? 106 LYS A NZ  1 
ATOM   789   N N   . SER A 1 142 ? 120.833 136.019 109.287 1.00 16.73  ? 107 SER A N   1 
ATOM   790   C CA  . SER A 1 142 ? 120.077 134.921 108.708 1.00 16.03  ? 107 SER A CA  1 
ATOM   791   C C   . SER A 1 142 ? 121.017 133.911 108.060 1.00 18.29  ? 107 SER A C   1 
ATOM   792   O O   . SER A 1 142 ? 122.185 134.196 107.786 1.00 21.90  ? 107 SER A O   1 
ATOM   793   C CB  . SER A 1 142 ? 119.068 135.440 107.686 1.00 12.45  ? 107 SER A CB  1 
ATOM   794   O OG  . SER A 1 142 ? 118.175 136.365 108.280 1.00 14.04  ? 107 SER A OG  1 
ATOM   795   N N   . VAL A 1 143 ? 120.488 132.716 107.815 1.00 17.51  ? 108 VAL A N   1 
ATOM   796   C CA  . VAL A 1 143 ? 121.247 131.615 107.235 1.00 17.21  ? 108 VAL A CA  1 
ATOM   797   C C   . VAL A 1 143 ? 120.425 131.014 106.107 1.00 17.79  ? 108 VAL A C   1 
ATOM   798   O O   . VAL A 1 143 ? 119.263 130.646 106.308 1.00 19.90  ? 108 VAL A O   1 
ATOM   799   C CB  . VAL A 1 143 ? 121.590 130.536 108.282 1.00 18.16  ? 108 VAL A CB  1 
ATOM   800   C CG1 . VAL A 1 143 ? 122.293 129.362 107.623 1.00 18.76  ? 108 VAL A CG1 1 
ATOM   801   C CG2 . VAL A 1 143 ? 122.446 131.116 109.397 1.00 19.75  ? 108 VAL A CG2 1 
ATOM   802   N N   . ALA A 1 144 ? 121.023 130.918 104.925 1.00 19.54  ? 109 ALA A N   1 
ATOM   803   C CA  . ALA A 1 144 ? 120.480 130.119 103.836 1.00 21.51  ? 109 ALA A CA  1 
ATOM   804   C C   . ALA A 1 144 ? 121.200 128.777 103.821 1.00 28.17  ? 109 ALA A C   1 
ATOM   805   O O   . ALA A 1 144 ? 122.421 128.725 103.640 1.00 38.52  ? 109 ALA A O   1 
ATOM   806   C CB  . ALA A 1 144 ? 120.635 130.835 102.495 1.00 23.41  ? 109 ALA A CB  1 
ATOM   807   N N   . HIS A 1 145 ? 120.444 127.700 104.005 1.00 22.29  ? 110 HIS A N   1 
ATOM   808   C CA  . HIS A 1 145 ? 121.036 126.382 104.191 1.00 24.10  ? 110 HIS A CA  1 
ATOM   809   C C   . HIS A 1 145 ? 121.566 125.842 102.870 1.00 30.39  ? 110 HIS A C   1 
ATOM   810   O O   . HIS A 1 145 ? 120.890 125.916 101.840 1.00 34.14  ? 110 HIS A O   1 
ATOM   811   C CB  . HIS A 1 145 ? 120.010 125.425 104.789 1.00 22.77  ? 110 HIS A CB  1 
ATOM   812   C CG  . HIS A 1 145 ? 119.484 125.864 106.118 1.00 20.01  ? 110 HIS A CG  1 
ATOM   813   N ND1 . HIS A 1 145 ? 120.166 125.647 107.295 1.00 19.02  ? 110 HIS A ND1 1 
ATOM   814   C CD2 . HIS A 1 145 ? 118.347 126.515 106.456 1.00 18.71  ? 110 HIS A CD2 1 
ATOM   815   C CE1 . HIS A 1 145 ? 119.469 126.142 108.302 1.00 16.69  ? 110 HIS A CE1 1 
ATOM   816   N NE2 . HIS A 1 145 ? 118.361 126.674 107.820 1.00 15.63  ? 110 HIS A NE2 1 
ATOM   817   N N   . ASN A 1 146 ? 122.787 125.309 102.899 1.00 32.54  ? 111 ASN A N   1 
ATOM   818   C CA  . ASN A 1 146 ? 123.492 124.914 101.687 1.00 37.35  ? 111 ASN A CA  1 
ATOM   819   C C   . ASN A 1 146 ? 123.958 123.465 101.779 1.00 37.60  ? 111 ASN A C   1 
ATOM   820   O O   . ASN A 1 146 ? 124.986 123.096 101.208 1.00 41.65  ? 111 ASN A O   1 
ATOM   821   C CB  . ASN A 1 146 ? 124.677 125.846 101.431 1.00 46.41  ? 111 ASN A CB  1 
ATOM   822   C CG  . ASN A 1 146 ? 125.040 125.942 99.968  1.00 52.38  ? 111 ASN A CG  1 
ATOM   823   O OD1 . ASN A 1 146 ? 124.170 126.074 99.115  1.00 52.80  ? 111 ASN A OD1 1 
ATOM   824   N ND2 . ASN A 1 146 ? 126.328 125.879 99.667  1.00 58.27  ? 111 ASN A ND2 1 
ATOM   825   N N   . MET A 1 147 ? 123.207 122.637 102.503 1.00 36.35  ? 112 MET A N   1 
ATOM   826   C CA  . MET A 1 147 ? 123.534 121.235 102.726 1.00 34.80  ? 112 MET A CA  1 
ATOM   827   C C   . MET A 1 147 ? 122.355 120.373 102.305 1.00 34.84  ? 112 MET A C   1 
ATOM   828   O O   . MET A 1 147 ? 121.218 120.657 102.691 1.00 35.35  ? 112 MET A O   1 
ATOM   829   C CB  . MET A 1 147 ? 123.859 120.975 104.197 1.00 37.96  ? 112 MET A CB  1 
ATOM   830   C CG  . MET A 1 147 ? 124.198 119.533 104.520 1.00 36.36  ? 112 MET A CG  1 
ATOM   831   S SD  . MET A 1 147 ? 125.832 119.072 103.932 1.00 66.93  ? 112 MET A SD  1 
ATOM   832   C CE  . MET A 1 147 ? 126.826 120.194 104.902 1.00 46.15  ? 112 MET A CE  1 
ATOM   833   N N   . THR A 1 148 ? 122.612 119.327 101.521 1.00 38.53  ? 113 THR A N   1 
ATOM   834   C CA  . THR A 1 148 ? 123.909 119.043 100.912 1.00 35.61  ? 113 THR A CA  1 
ATOM   835   C C   . THR A 1 148 ? 124.116 119.946 99.703  1.00 37.58  ? 113 THR A C   1 
ATOM   836   O O   . THR A 1 148 ? 125.242 120.273 99.331  1.00 36.44  ? 113 THR A O   1 
ATOM   837   C CB  . THR A 1 148 ? 124.031 117.568 100.490 1.00 32.36  ? 113 THR A CB  1 
ATOM   838   O OG1 . THR A 1 148 ? 122.949 117.227 99.616  1.00 38.74  ? 113 THR A OG1 1 
ATOM   839   C CG2 . THR A 1 148 ? 123.992 116.663 101.709 1.00 29.23  ? 113 THR A CG2 1 
ATOM   840   N N   . MET A 1 149 ? 123.004 120.331 99.099  1.00 37.12  ? 114 MET A N   1 
ATOM   841   C CA  . MET A 1 149 ? 122.919 121.293 98.017  1.00 38.49  ? 114 MET A CA  1 
ATOM   842   C C   . MET A 1 149 ? 122.240 122.567 98.510  1.00 41.44  ? 114 MET A C   1 
ATOM   843   O O   . MET A 1 149 ? 121.738 122.618 99.638  1.00 37.51  ? 114 MET A O   1 
ATOM   844   C CB  . MET A 1 149 ? 122.135 120.681 96.849  1.00 38.21  ? 114 MET A CB  1 
ATOM   845   C CG  . MET A 1 149 ? 122.756 119.412 96.297  1.00 48.50  ? 114 MET A CG  1 
ATOM   846   S SD  . MET A 1 149 ? 124.338 119.725 95.490  1.00 65.48  ? 114 MET A SD  1 
ATOM   847   C CE  . MET A 1 149 ? 123.796 120.514 93.978  1.00 62.64  ? 114 MET A CE  1 
ATOM   848   N N   . PRO A 1 150 ? 122.229 123.632 97.704  1.00 45.19  ? 115 PRO A N   1 
ATOM   849   C CA  . PRO A 1 150 ? 121.482 124.832 98.106  1.00 37.79  ? 115 PRO A CA  1 
ATOM   850   C C   . PRO A 1 150 ? 120.010 124.524 98.332  1.00 33.37  ? 115 PRO A C   1 
ATOM   851   O O   . PRO A 1 150 ? 119.333 123.962 97.468  1.00 34.77  ? 115 PRO A O   1 
ATOM   852   C CB  . PRO A 1 150 ? 121.688 125.792 96.929  1.00 36.41  ? 115 PRO A CB  1 
ATOM   853   C CG  . PRO A 1 150 ? 122.934 125.332 96.279  1.00 44.96  ? 115 PRO A CG  1 
ATOM   854   C CD  . PRO A 1 150 ? 122.972 123.851 96.448  1.00 46.85  ? 115 PRO A CD  1 
ATOM   855   N N   . ASN A 1 151 ? 119.519 124.904 99.512  1.00 27.26  ? 116 ASN A N   1 
ATOM   856   C CA  . ASN A 1 151 ? 118.131 124.662 99.901  1.00 21.06  ? 116 ASN A CA  1 
ATOM   857   C C   . ASN A 1 151 ? 117.208 125.691 99.247  1.00 19.32  ? 116 ASN A C   1 
ATOM   858   O O   . ASN A 1 151 ? 116.552 126.501 99.899  1.00 18.95  ? 116 ASN A O   1 
ATOM   859   C CB  . ASN A 1 151 ? 117.991 124.671 101.418 1.00 19.39  ? 116 ASN A CB  1 
ATOM   860   C CG  . ASN A 1 151 ? 118.592 123.440 102.069 1.00 22.09  ? 116 ASN A CG  1 
ATOM   861   O OD1 . ASN A 1 151 ? 118.367 123.178 103.250 1.00 19.10  ? 116 ASN A OD1 1 
ATOM   862   N ND2 . ASN A 1 151 ? 119.350 122.670 101.300 1.00 26.82  ? 116 ASN A ND2 1 
ATOM   863   N N   . LYS A 1 152 ? 117.183 125.646 97.919  1.00 20.92  ? 117 LYS A N   1 
ATOM   864   C CA  . LYS A 1 152 ? 116.382 126.552 97.114  1.00 17.83  ? 117 LYS A CA  1 
ATOM   865   C C   . LYS A 1 152 ? 115.707 125.751 96.015  1.00 19.44  ? 117 LYS A C   1 
ATOM   866   O O   . LYS A 1 152 ? 116.184 124.689 95.609  1.00 28.23  ? 117 LYS A O   1 
ATOM   867   C CB  . LYS A 1 152 ? 117.219 127.681 96.495  1.00 20.64  ? 117 LYS A CB  1 
ATOM   868   C CG  . LYS A 1 152 ? 117.952 128.555 97.493  1.00 26.58  ? 117 LYS A CG  1 
ATOM   869   C CD  . LYS A 1 152 ? 118.752 129.633 96.781  1.00 26.60  ? 117 LYS A CD  1 
ATOM   870   C CE  . LYS A 1 152 ? 119.433 130.561 97.773  1.00 31.08  ? 117 LYS A CE  1 
ATOM   871   N NZ  . LYS A 1 152 ? 120.289 131.573 97.093  1.00 32.66  ? 117 LYS A NZ  1 
ATOM   872   N N   . LEU A 1 153 ? 114.587 126.275 95.531  1.00 19.52  ? 118 LEU A N   1 
ATOM   873   C CA  . LEU A 1 153 ? 113.892 125.661 94.412  1.00 25.55  ? 118 LEU A CA  1 
ATOM   874   C C   . LEU A 1 153 ? 113.135 126.746 93.671  1.00 26.26  ? 118 LEU A C   1 
ATOM   875   O O   . LEU A 1 153 ? 112.415 127.536 94.287  1.00 27.49  ? 118 LEU A O   1 
ATOM   876   C CB  . LEU A 1 153 ? 112.926 124.572 94.887  1.00 25.70  ? 118 LEU A CB  1 
ATOM   877   C CG  . LEU A 1 153 ? 112.209 123.770 93.802  1.00 32.46  ? 118 LEU A CG  1 
ATOM   878   C CD1 . LEU A 1 153 ? 113.206 123.103 92.866  1.00 36.50  ? 118 LEU A CD1 1 
ATOM   879   C CD2 . LEU A 1 153 ? 111.276 122.750 94.426  1.00 38.27  ? 118 LEU A CD2 1 
ATOM   880   N N   . LEU A 1 154 ? 113.305 126.780 92.355  1.00 30.76  ? 119 LEU A N   1 
ATOM   881   C CA  . LEU A 1 154 ? 112.648 127.766 91.511  1.00 33.35  ? 119 LEU A CA  1 
ATOM   882   C C   . LEU A 1 154 ? 111.908 127.037 90.401  1.00 40.11  ? 119 LEU A C   1 
ATOM   883   O O   . LEU A 1 154 ? 112.525 126.311 89.615  1.00 54.56  ? 119 LEU A O   1 
ATOM   884   C CB  . LEU A 1 154 ? 113.673 128.750 90.946  1.00 36.78  ? 119 LEU A CB  1 
ATOM   885   C CG  . LEU A 1 154 ? 113.219 129.816 89.957  1.00 41.01  ? 119 LEU A CG  1 
ATOM   886   C CD1 . LEU A 1 154 ? 112.010 130.551 90.491  1.00 44.85  ? 119 LEU A CD1 1 
ATOM   887   C CD2 . LEU A 1 154 ? 114.363 130.775 89.746  1.00 47.76  ? 119 LEU A CD2 1 
ATOM   888   N N   . ARG A 1 155 ? 110.596 127.228 90.339  1.00 32.72  ? 120 ARG A N   1 
ATOM   889   C CA  . ARG A 1 155 ? 109.760 126.627 89.315  1.00 39.09  ? 120 ARG A CA  1 
ATOM   890   C C   . ARG A 1 155 ? 109.166 127.706 88.422  1.00 41.18  ? 120 ARG A C   1 
ATOM   891   O O   . ARG A 1 155 ? 108.952 128.841 88.851  1.00 45.55  ? 120 ARG A O   1 
ATOM   892   C CB  . ARG A 1 155 ? 108.642 125.778 89.926  1.00 43.58  ? 120 ARG A CB  1 
ATOM   893   C CG  . ARG A 1 155 ? 109.134 124.564 90.690  1.00 50.46  ? 120 ARG A CG  1 
ATOM   894   C CD  . ARG A 1 155 ? 108.003 123.892 91.446  1.00 54.00  ? 120 ARG A CD  1 
ATOM   895   N NE  . ARG A 1 155 ? 108.481 122.806 92.292  1.00 60.43  ? 120 ARG A NE  1 
ATOM   896   C CZ  . ARG A 1 155 ? 107.787 122.271 93.286  1.00 64.74  ? 120 ARG A CZ  1 
ATOM   897   N NH1 . ARG A 1 155 ? 106.575 122.704 93.594  1.00 71.61  ? 120 ARG A NH1 1 
ATOM   898   N NH2 . ARG A 1 155 ? 108.318 121.273 93.986  1.00 59.98  ? 120 ARG A NH2 1 
ATOM   899   N N   . ILE A 1 156 ? 108.909 127.340 87.169  1.00 46.33  ? 121 ILE A N   1 
ATOM   900   C CA  . ILE A 1 156 ? 108.307 128.235 86.189  1.00 49.30  ? 121 ILE A CA  1 
ATOM   901   C C   . ILE A 1 156 ? 107.128 127.516 85.553  1.00 56.17  ? 121 ILE A C   1 
ATOM   902   O O   . ILE A 1 156 ? 107.274 126.392 85.060  1.00 61.11  ? 121 ILE A O   1 
ATOM   903   C CB  . ILE A 1 156 ? 109.316 128.661 85.106  1.00 51.38  ? 121 ILE A CB  1 
ATOM   904   C CG1 . ILE A 1 156 ? 110.613 129.165 85.738  1.00 46.08  ? 121 ILE A CG1 1 
ATOM   905   C CG2 . ILE A 1 156 ? 108.715 129.723 84.202  1.00 54.62  ? 121 ILE A CG2 1 
ATOM   906   C CD1 . ILE A 1 156 ? 111.692 129.483 84.727  1.00 55.51  ? 121 ILE A CD1 1 
ATOM   907   N N   . THR A 1 157 ? 105.967 128.158 85.565  1.00 55.19  ? 122 THR A N   1 
ATOM   908   C CA  . THR A 1 157 ? 104.811 127.662 84.837  1.00 62.14  ? 122 THR A CA  1 
ATOM   909   C C   . THR A 1 157 ? 104.819 128.228 83.417  1.00 67.75  ? 122 THR A C   1 
ATOM   910   O O   . THR A 1 157 ? 105.490 129.221 83.127  1.00 66.03  ? 122 THR A O   1 
ATOM   911   C CB  . THR A 1 157 ? 103.528 128.052 85.585  1.00 63.88  ? 122 THR A CB  1 
ATOM   912   O OG1 . THR A 1 157 ? 103.605 127.568 86.931  1.00 68.28  ? 122 THR A OG1 1 
ATOM   913   C CG2 . THR A 1 157 ? 102.288 127.441 84.941  1.00 70.52  ? 122 THR A CG2 1 
ATOM   914   N N   . GLU A 1 158 ? 104.081 127.562 82.521  1.00 75.39  ? 123 GLU A N   1 
ATOM   915   C CA  . GLU A 1 158 ? 104.038 127.980 81.121  1.00 78.55  ? 123 GLU A CA  1 
ATOM   916   C C   . GLU A 1 158 ? 103.648 129.449 80.986  1.00 75.58  ? 123 GLU A C   1 
ATOM   917   O O   . GLU A 1 158 ? 104.143 130.153 80.099  1.00 69.19  ? 123 GLU A O   1 
ATOM   918   C CB  . GLU A 1 158 ? 103.082 127.078 80.334  1.00 81.13  ? 123 GLU A CB  1 
ATOM   919   C CG  . GLU A 1 158 ? 101.604 127.270 80.643  1.00 81.99  ? 123 GLU A CG  1 
ATOM   920   C CD  . GLU A 1 158 ? 100.732 126.206 80.005  1.00 89.85  ? 123 GLU A CD  1 
ATOM   921   O OE1 . GLU A 1 158 ? 101.282 125.316 79.322  1.00 96.94  ? 123 GLU A OE1 1 
ATOM   922   O OE2 . GLU A 1 158 ? 99.497  126.261 80.183  1.00 80.06  ? 123 GLU A OE2 1 
ATOM   923   N N   . ASP A 1 159 ? 102.757 129.927 81.859  1.00 76.59  ? 124 ASP A N   1 
ATOM   924   C CA  . ASP A 1 159 ? 102.273 131.302 81.807  1.00 70.26  ? 124 ASP A CA  1 
ATOM   925   C C   . ASP A 1 159 ? 103.356 132.307 82.182  1.00 66.32  ? 124 ASP A C   1 
ATOM   926   O O   . ASP A 1 159 ? 103.169 133.510 81.976  1.00 60.70  ? 124 ASP A O   1 
ATOM   927   C CB  . ASP A 1 159 ? 101.067 131.448 82.742  1.00 66.06  ? 124 ASP A CB  1 
ATOM   928   C CG  . ASP A 1 159 ? 100.261 132.713 82.486  1.00 66.22  ? 124 ASP A CG  1 
ATOM   929   O OD1 . ASP A 1 159 ? 100.602 133.483 81.565  1.00 66.78  ? 124 ASP A OD1 1 
ATOM   930   O OD2 . ASP A 1 159 ? 99.275  132.938 83.218  1.00 73.42  ? 124 ASP A OD2 1 
ATOM   931   N N   . GLY A 1 160 ? 104.485 131.842 82.704  1.00 69.19  ? 125 GLY A N   1 
ATOM   932   C CA  . GLY A 1 160 ? 105.531 132.713 83.192  1.00 59.03  ? 125 GLY A CA  1 
ATOM   933   C C   . GLY A 1 160 ? 105.471 133.002 84.672  1.00 45.82  ? 125 GLY A C   1 
ATOM   934   O O   . GLY A 1 160 ? 106.174 133.905 85.140  1.00 39.92  ? 125 GLY A O   1 
ATOM   935   N N   . THR A 1 161 ? 104.652 132.272 85.422  1.00 47.97  ? 126 THR A N   1 
ATOM   936   C CA  . THR A 1 161 ? 104.591 132.432 86.866  1.00 43.25  ? 126 THR A CA  1 
ATOM   937   C C   . THR A 1 161 ? 105.740 131.667 87.504  1.00 39.62  ? 126 THR A C   1 
ATOM   938   O O   . THR A 1 161 ? 105.922 130.474 87.242  1.00 48.68  ? 126 THR A O   1 
ATOM   939   C CB  . THR A 1 161 ? 103.254 131.929 87.408  1.00 47.36  ? 126 THR A CB  1 
ATOM   940   O OG1 . THR A 1 161 ? 102.182 132.652 86.790  1.00 47.19  ? 126 THR A OG1 1 
ATOM   941   C CG2 . THR A 1 161 ? 103.186 132.124 88.914  1.00 40.12  ? 126 THR A CG2 1 
ATOM   942   N N   . LEU A 1 162 ? 106.518 132.347 88.337  1.00 31.22  ? 127 LEU A N   1 
ATOM   943   C CA  . LEU A 1 162 ? 107.651 131.733 89.014  1.00 31.82  ? 127 LEU A CA  1 
ATOM   944   C C   . LEU A 1 162 ? 107.290 131.486 90.471  1.00 26.74  ? 127 LEU A C   1 
ATOM   945   O O   . LEU A 1 162 ? 106.929 132.420 91.192  1.00 28.60  ? 127 LEU A O   1 
ATOM   946   C CB  . LEU A 1 162 ? 108.903 132.603 88.917  1.00 29.17  ? 127 LEU A CB  1 
ATOM   947   C CG  . LEU A 1 162 ? 109.500 132.844 87.530  1.00 33.69  ? 127 LEU A CG  1 
ATOM   948   C CD1 . LEU A 1 162 ? 108.893 134.069 86.870  1.00 38.13  ? 127 LEU A CD1 1 
ATOM   949   C CD2 . LEU A 1 162 ? 111.009 132.974 87.627  1.00 34.14  ? 127 LEU A CD2 1 
ATOM   950   N N   . LEU A 1 163 ? 107.391 130.233 90.899  1.00 26.52  ? 128 LEU A N   1 
ATOM   951   C CA  . LEU A 1 163 ? 107.321 129.884 92.308  1.00 25.25  ? 128 LEU A CA  1 
ATOM   952   C C   . LEU A 1 163 ? 108.735 129.625 92.797  1.00 26.08  ? 128 LEU A C   1 
ATOM   953   O O   . LEU A 1 163 ? 109.451 128.793 92.231  1.00 32.27  ? 128 LEU A O   1 
ATOM   954   C CB  . LEU A 1 163 ? 106.441 128.654 92.537  1.00 25.93  ? 128 LEU A CB  1 
ATOM   955   C CG  . LEU A 1 163 ? 106.304 128.200 93.992  1.00 21.34  ? 128 LEU A CG  1 
ATOM   956   C CD1 . LEU A 1 163 ? 105.655 129.284 94.833  1.00 24.72  ? 128 LEU A CD1 1 
ATOM   957   C CD2 . LEU A 1 163 ? 105.512 126.907 94.085  1.00 20.48  ? 128 LEU A CD2 1 
ATOM   958   N N   . TYR A 1 164 ? 109.128 130.331 93.851  1.00 21.64  ? 129 TYR A N   1 
ATOM   959   C CA  . TYR A 1 164 ? 110.508 130.348 94.310  1.00 21.34  ? 129 TYR A CA  1 
ATOM   960   C C   . TYR A 1 164 ? 110.500 130.134 95.813  1.00 17.98  ? 129 TYR A C   1 
ATOM   961   O O   . TYR A 1 164 ? 109.942 130.947 96.554  1.00 21.07  ? 129 TYR A O   1 
ATOM   962   C CB  . TYR A 1 164 ? 111.182 131.668 93.925  1.00 23.31  ? 129 TYR A CB  1 
ATOM   963   C CG  . TYR A 1 164 ? 112.642 131.772 94.282  1.00 25.52  ? 129 TYR A CG  1 
ATOM   964   C CD1 . TYR A 1 164 ? 113.526 130.750 93.970  1.00 25.56  ? 129 TYR A CD1 1 
ATOM   965   C CD2 . TYR A 1 164 ? 113.148 132.916 94.877  1.00 30.18  ? 129 TYR A CD2 1 
ATOM   966   C CE1 . TYR A 1 164 ? 114.865 130.848 94.276  1.00 31.39  ? 129 TYR A CE1 1 
ATOM   967   C CE2 . TYR A 1 164 ? 114.486 133.027 95.180  1.00 34.18  ? 129 TYR A CE2 1 
ATOM   968   C CZ  . TYR A 1 164 ? 115.340 131.989 94.883  1.00 36.56  ? 129 TYR A CZ  1 
ATOM   969   O OH  . TYR A 1 164 ? 116.676 132.096 95.189  1.00 48.02  ? 129 TYR A OH  1 
ATOM   970   N N   . THR A 1 165 ? 111.118 129.046 96.259  1.00 16.67  ? 130 THR A N   1 
ATOM   971   C CA  . THR A 1 165 ? 111.131 128.675 97.662  1.00 16.91  ? 130 THR A CA  1 
ATOM   972   C C   . THR A 1 165 ? 112.564 128.513 98.146  1.00 18.01  ? 130 THR A C   1 
ATOM   973   O O   . THR A 1 165 ? 113.461 128.149 97.380  1.00 23.93  ? 130 THR A O   1 
ATOM   974   C CB  . THR A 1 165 ? 110.355 127.362 97.880  1.00 19.35  ? 130 THR A CB  1 
ATOM   975   O OG1 . THR A 1 165 ? 109.082 127.444 97.229  1.00 23.31  ? 130 THR A OG1 1 
ATOM   976   C CG2 . THR A 1 165 ? 110.139 127.084 99.359  1.00 19.56  ? 130 THR A CG2 1 
ATOM   977   N N   . MET A 1 166 ? 112.766 128.776 99.434  1.00 15.57  ? 131 MET A N   1 
ATOM   978   C CA  . MET A 1 166 ? 114.056 128.583 100.071 1.00 16.10  ? 131 MET A CA  1 
ATOM   979   C C   . MET A 1 166 ? 113.825 128.265 101.537 1.00 13.36  ? 131 MET A C   1 
ATOM   980   O O   . MET A 1 166 ? 112.802 128.629 102.118 1.00 13.33  ? 131 MET A O   1 
ATOM   981   C CB  . MET A 1 166 ? 114.962 129.812 99.940  1.00 18.82  ? 131 MET A CB  1 
ATOM   982   C CG  . MET A 1 166 ? 114.399 131.064 100.580 1.00 21.58  ? 131 MET A CG  1 
ATOM   983   S SD  . MET A 1 166 ? 115.386 132.525 100.216 1.00 51.17  ? 131 MET A SD  1 
ATOM   984   C CE  . MET A 1 166 ? 115.118 132.672 98.460  1.00 27.21  ? 131 MET A CE  1 
ATOM   985   N N   . ARG A 1 167 ? 114.796 127.582 102.129 1.00 12.15  ? 132 ARG A N   1 
ATOM   986   C CA  . ARG A 1 167 ? 114.742 127.179 103.525 1.00 10.82  ? 132 ARG A CA  1 
ATOM   987   C C   . ARG A 1 167 ? 115.734 128.039 104.289 1.00 13.17  ? 132 ARG A C   1 
ATOM   988   O O   . ARG A 1 167 ? 116.935 128.014 104.001 1.00 21.71  ? 132 ARG A O   1 
ATOM   989   C CB  . ARG A 1 167 ? 115.059 125.694 103.683 1.00 11.84  ? 132 ARG A CB  1 
ATOM   990   C CG  . ARG A 1 167 ? 115.004 125.202 105.110 1.00 12.31  ? 132 ARG A CG  1 
ATOM   991   C CD  . ARG A 1 167 ? 115.216 123.706 105.172 1.00 13.36  ? 132 ARG A CD  1 
ATOM   992   N NE  . ARG A 1 167 ? 115.564 123.268 106.515 1.00 16.97  ? 132 ARG A NE  1 
ATOM   993   C CZ  . ARG A 1 167 ? 116.795 122.972 106.905 1.00 22.65  ? 132 ARG A CZ  1 
ATOM   994   N NH1 . ARG A 1 167 ? 117.814 123.006 106.063 1.00 16.63  ? 132 ARG A NH1 1 
ATOM   995   N NH2 . ARG A 1 167 ? 117.008 122.624 108.171 1.00 30.78  ? 132 ARG A NH2 1 
ATOM   996   N N   . LEU A 1 168 ? 115.231 128.796 105.257 1.00 9.78   ? 133 LEU A N   1 
ATOM   997   C CA  . LEU A 1 168 ? 116.009 129.807 105.948 1.00 12.17  ? 133 LEU A CA  1 
ATOM   998   C C   . LEU A 1 168 ? 115.892 129.636 107.452 1.00 12.93  ? 133 LEU A C   1 
ATOM   999   O O   . LEU A 1 168 ? 114.852 129.226 107.972 1.00 14.82  ? 133 LEU A O   1 
ATOM   1000  C CB  . LEU A 1 168 ? 115.553 131.224 105.576 1.00 10.74  ? 133 LEU A CB  1 
ATOM   1001  C CG  . LEU A 1 168 ? 115.377 131.545 104.095 1.00 10.33  ? 133 LEU A CG  1 
ATOM   1002  C CD1 . LEU A 1 168 ? 114.580 132.822 103.926 1.00 9.26   ? 133 LEU A CD1 1 
ATOM   1003  C CD2 . LEU A 1 168 ? 116.731 131.668 103.427 1.00 13.50  ? 133 LEU A CD2 1 
ATOM   1004  N N   . THR A 1 169 ? 116.982 129.946 108.138 1.00 13.73  ? 134 THR A N   1 
ATOM   1005  C CA  . THR A 1 169 ? 116.983 130.133 109.581 1.00 14.91  ? 134 THR A CA  1 
ATOM   1006  C C   . THR A 1 169 ? 117.228 131.618 109.802 1.00 14.73  ? 134 THR A C   1 
ATOM   1007  O O   . THR A 1 169 ? 118.308 132.128 109.488 1.00 17.01  ? 134 THR A O   1 
ATOM   1008  C CB  . THR A 1 169 ? 118.053 129.279 110.254 1.00 20.11  ? 134 THR A CB  1 
ATOM   1009  O OG1 . THR A 1 169 ? 117.761 127.892 110.048 1.00 23.26  ? 134 THR A OG1 1 
ATOM   1010  C CG2 . THR A 1 169 ? 118.117 129.567 111.741 1.00 17.67  ? 134 THR A CG2 1 
ATOM   1011  N N   . VAL A 1 170 ? 116.225 132.306 110.337 1.00 16.32  ? 135 VAL A N   1 
ATOM   1012  C CA  . VAL A 1 170 ? 116.241 133.757 110.469 1.00 16.52  ? 135 VAL A CA  1 
ATOM   1013  C C   . VAL A 1 170 ? 116.347 134.123 111.939 1.00 16.18  ? 135 VAL A C   1 
ATOM   1014  O O   . VAL A 1 170 ? 115.533 133.680 112.758 1.00 19.87  ? 135 VAL A O   1 
ATOM   1015  C CB  . VAL A 1 170 ? 114.984 134.386 109.845 1.00 13.20  ? 135 VAL A CB  1 
ATOM   1016  C CG1 . VAL A 1 170 ? 114.986 135.890 110.049 1.00 13.01  ? 135 VAL A CG1 1 
ATOM   1017  C CG2 . VAL A 1 170 ? 114.892 134.038 108.370 1.00 12.07  ? 135 VAL A CG2 1 
ATOM   1018  N N   . ARG A 1 171 ? 117.348 134.930 112.271 1.00 13.19  ? 136 ARG A N   1 
ATOM   1019  C CA  . ARG A 1 171 ? 117.372 135.644 113.536 1.00 16.96  ? 136 ARG A CA  1 
ATOM   1020  C C   . ARG A 1 171 ? 116.797 137.032 113.296 1.00 19.92  ? 136 ARG A C   1 
ATOM   1021  O O   . ARG A 1 171 ? 117.242 137.742 112.390 1.00 25.64  ? 136 ARG A O   1 
ATOM   1022  C CB  . ARG A 1 171 ? 118.799 135.739 114.068 1.00 22.03  ? 136 ARG A CB  1 
ATOM   1023  C CG  . ARG A 1 171 ? 119.364 134.431 114.578 1.00 23.44  ? 136 ARG A CG  1 
ATOM   1024  C CD  . ARG A 1 171 ? 119.949 134.605 115.961 1.00 30.33  ? 136 ARG A CD  1 
ATOM   1025  N NE  . ARG A 1 171 ? 120.760 135.815 116.027 1.00 39.19  ? 136 ARG A NE  1 
ATOM   1026  C CZ  . ARG A 1 171 ? 122.021 135.894 115.623 1.00 43.35  ? 136 ARG A CZ  1 
ATOM   1027  N NH1 . ARG A 1 171 ? 122.650 134.848 115.113 1.00 41.51  ? 136 ARG A NH1 1 
ATOM   1028  N NH2 . ARG A 1 171 ? 122.665 137.052 115.729 1.00 40.09  ? 136 ARG A NH2 1 
ATOM   1029  N N   . ALA A 1 172 ? 115.815 137.418 114.101 1.00 18.17  ? 137 ALA A N   1 
ATOM   1030  C CA  . ALA A 1 172 ? 115.101 138.662 113.871 1.00 18.35  ? 137 ALA A CA  1 
ATOM   1031  C C   . ALA A 1 172 ? 115.008 139.456 115.162 1.00 22.91  ? 137 ALA A C   1 
ATOM   1032  O O   . ALA A 1 172 ? 115.058 138.895 116.257 1.00 29.30  ? 137 ALA A O   1 
ATOM   1033  C CB  . ALA A 1 172 ? 113.695 138.405 113.318 1.00 18.91  ? 137 ALA A CB  1 
ATOM   1034  N N   . GLU A 1 173 ? 114.876 140.772 115.023 1.00 24.10  ? 138 GLU A N   1 
ATOM   1035  C CA  . GLU A 1 173 ? 114.763 141.641 116.183 1.00 25.80  ? 138 GLU A CA  1 
ATOM   1036  C C   . GLU A 1 173 ? 113.339 141.594 116.720 1.00 29.80  ? 138 GLU A C   1 
ATOM   1037  O O   . GLU A 1 173 ? 112.375 141.730 115.962 1.00 28.87  ? 138 GLU A O   1 
ATOM   1038  C CB  . GLU A 1 173 ? 115.149 143.079 115.834 1.00 27.24  ? 138 GLU A CB  1 
ATOM   1039  C CG  . GLU A 1 173 ? 116.519 143.237 115.198 1.00 26.63  ? 138 GLU A CG  1 
ATOM   1040  C CD  . GLU A 1 173 ? 116.655 144.536 114.424 1.00 32.36  ? 138 GLU A CD  1 
ATOM   1041  O OE1 . GLU A 1 173 ? 115.752 145.393 114.534 1.00 33.36  ? 138 GLU A OE1 1 
ATOM   1042  O OE2 . GLU A 1 173 ? 117.664 144.702 113.706 1.00 27.80  ? 138 GLU A OE2 1 
ATOM   1043  N N   . CYS A 1 174 ? 113.210 141.395 118.029 1.00 33.64  ? 139 CYS A N   1 
ATOM   1044  C CA  . CYS A 1 174 ? 111.922 141.435 118.716 1.00 38.02  ? 139 CYS A CA  1 
ATOM   1045  C C   . CYS A 1 174 ? 112.094 142.347 119.919 1.00 44.78  ? 139 CYS A C   1 
ATOM   1046  O O   . CYS A 1 174 ? 112.447 141.887 121.014 1.00 48.78  ? 139 CYS A O   1 
ATOM   1047  C CB  . CYS A 1 174 ? 111.450 140.042 119.130 1.00 38.73  ? 139 CYS A CB  1 
ATOM   1048  S SG  . CYS A 1 174 ? 109.824 140.037 119.937 1.00 63.60  ? 139 CYS A SG  1 
ATOM   1049  N N   . PRO A 1 175 ? 111.875 143.651 119.752 1.00 45.25  ? 140 PRO A N   1 
ATOM   1050  C CA  . PRO A 1 175 ? 111.974 144.557 120.901 1.00 46.09  ? 140 PRO A CA  1 
ATOM   1051  C C   . PRO A 1 175 ? 110.944 144.178 121.952 1.00 47.64  ? 140 PRO A C   1 
ATOM   1052  O O   . PRO A 1 175 ? 109.751 144.062 121.667 1.00 48.09  ? 140 PRO A O   1 
ATOM   1053  C CB  . PRO A 1 175 ? 111.692 145.937 120.295 1.00 47.22  ? 140 PRO A CB  1 
ATOM   1054  C CG  . PRO A 1 175 ? 111.936 145.776 118.832 1.00 46.47  ? 140 PRO A CG  1 
ATOM   1055  C CD  . PRO A 1 175 ? 111.559 144.367 118.507 1.00 44.89  ? 140 PRO A CD  1 
ATOM   1056  N N   . MET A 1 176 ? 111.420 143.980 123.175 1.00 43.30  ? 141 MET A N   1 
ATOM   1057  C CA  . MET A 1 176 ? 110.586 143.532 124.278 1.00 42.19  ? 141 MET A CA  1 
ATOM   1058  C C   . MET A 1 176 ? 110.546 144.589 125.367 1.00 45.37  ? 141 MET A C   1 
ATOM   1059  O O   . MET A 1 176 ? 111.594 145.069 125.810 1.00 46.96  ? 141 MET A O   1 
ATOM   1060  C CB  . MET A 1 176 ? 111.106 142.213 124.850 1.00 38.71  ? 141 MET A CB  1 
ATOM   1061  C CG  . MET A 1 176 ? 111.071 141.064 123.864 1.00 43.93  ? 141 MET A CG  1 
ATOM   1062  S SD  . MET A 1 176 ? 111.890 139.589 124.487 1.00 60.45  ? 141 MET A SD  1 
ATOM   1063  C CE  . MET A 1 176 ? 111.938 138.604 122.998 1.00 48.83  ? 141 MET A CE  1 
ATOM   1064  N N   . HIS A 1 177 ? 109.341 144.952 125.789 1.00 43.81  ? 142 HIS A N   1 
ATOM   1065  C CA  . HIS A 1 177 ? 109.150 145.801 126.956 1.00 41.56  ? 142 HIS A CA  1 
ATOM   1066  C C   . HIS A 1 177 ? 108.874 144.855 128.116 1.00 39.79  ? 142 HIS A C   1 
ATOM   1067  O O   . HIS A 1 177 ? 107.788 144.273 128.210 1.00 44.04  ? 142 HIS A O   1 
ATOM   1068  C CB  . HIS A 1 177 ? 108.007 146.791 126.747 1.00 49.44  ? 142 HIS A CB  1 
ATOM   1069  C CG  . HIS A 1 177 ? 108.188 147.679 125.556 1.00 63.08  ? 142 HIS A CG  1 
ATOM   1070  N ND1 . HIS A 1 177 ? 108.110 147.214 124.261 1.00 64.27  ? 142 HIS A ND1 1 
ATOM   1071  C CD2 . HIS A 1 177 ? 108.444 149.005 125.464 1.00 68.46  ? 142 HIS A CD2 1 
ATOM   1072  C CE1 . HIS A 1 177 ? 108.308 148.216 123.423 1.00 65.27  ? 142 HIS A CE1 1 
ATOM   1073  N NE2 . HIS A 1 177 ? 108.514 149.314 124.127 1.00 70.69  ? 142 HIS A NE2 1 
ATOM   1074  N N   . LEU A 1 178 ? 109.861 144.700 128.997 1.00 34.09  ? 143 LEU A N   1 
ATOM   1075  C CA  . LEU A 1 178 ? 109.833 143.681 130.036 1.00 30.35  ? 143 LEU A CA  1 
ATOM   1076  C C   . LEU A 1 178 ? 109.387 144.227 131.385 1.00 33.22  ? 143 LEU A C   1 
ATOM   1077  O O   . LEU A 1 178 ? 109.829 143.732 132.425 1.00 35.80  ? 143 LEU A O   1 
ATOM   1078  C CB  . LEU A 1 178 ? 111.207 143.026 130.157 1.00 28.71  ? 143 LEU A CB  1 
ATOM   1079  C CG  . LEU A 1 178 ? 111.723 142.393 128.865 1.00 31.13  ? 143 LEU A CG  1 
ATOM   1080  C CD1 . LEU A 1 178 ? 113.132 141.880 129.048 1.00 31.91  ? 143 LEU A CD1 1 
ATOM   1081  C CD2 . LEU A 1 178 ? 110.807 141.273 128.420 1.00 35.77  ? 143 LEU A CD2 1 
ATOM   1082  N N   . GLU A 1 179 ? 108.519 145.238 131.394 1.00 34.42  ? 144 GLU A N   1 
ATOM   1083  C CA  . GLU A 1 179 ? 108.042 145.771 132.666 1.00 30.91  ? 144 GLU A CA  1 
ATOM   1084  C C   . GLU A 1 179 ? 107.232 144.735 133.436 1.00 30.82  ? 144 GLU A C   1 
ATOM   1085  O O   . GLU A 1 179 ? 107.342 144.644 134.663 1.00 34.81  ? 144 GLU A O   1 
ATOM   1086  C CB  . GLU A 1 179 ? 107.221 147.043 132.447 1.00 34.37  ? 144 GLU A CB  1 
ATOM   1087  C CG  . GLU A 1 179 ? 107.963 148.167 131.739 1.00 38.33  ? 144 GLU A CG  1 
ATOM   1088  C CD  . GLU A 1 179 ? 107.904 148.058 130.234 1.00 47.99  ? 144 GLU A CD  1 
ATOM   1089  O OE1 . GLU A 1 179 ? 106.907 147.514 129.716 1.00 51.61  ? 144 GLU A OE1 1 
ATOM   1090  O OE2 . GLU A 1 179 ? 108.853 148.523 129.568 1.00 47.29  ? 144 GLU A OE2 1 
ATOM   1091  N N   . ASP A 1 180 ? 106.416 143.944 132.741 1.00 29.26  ? 145 ASP A N   1 
ATOM   1092  C CA  . ASP A 1 180 ? 105.582 142.951 133.403 1.00 26.94  ? 145 ASP A CA  1 
ATOM   1093  C C   . ASP A 1 180 ? 106.233 141.574 133.507 1.00 27.34  ? 145 ASP A C   1 
ATOM   1094  O O   . ASP A 1 180 ? 105.549 140.614 133.874 1.00 29.96  ? 145 ASP A O   1 
ATOM   1095  C CB  . ASP A 1 180 ? 104.244 142.828 132.671 1.00 28.21  ? 145 ASP A CB  1 
ATOM   1096  C CG  . ASP A 1 180 ? 103.452 144.120 132.683 1.00 33.67  ? 145 ASP A CG  1 
ATOM   1097  O OD1 . ASP A 1 180 ? 104.020 145.160 133.074 1.00 34.19  ? 145 ASP A OD1 1 
ATOM   1098  O OD2 . ASP A 1 180 ? 102.263 144.096 132.304 1.00 37.28  ? 145 ASP A OD2 1 
ATOM   1099  N N   . PHE A 1 181 ? 107.520 141.455 133.194 1.00 24.17  ? 146 PHE A N   1 
ATOM   1100  C CA  . PHE A 1 181 ? 108.202 140.171 133.287 1.00 22.49  ? 146 PHE A CA  1 
ATOM   1101  C C   . PHE A 1 181 ? 108.092 139.620 134.708 1.00 24.70  ? 146 PHE A C   1 
ATOM   1102  O O   . PHE A 1 181 ? 108.278 140.366 135.674 1.00 29.53  ? 146 PHE A O   1 
ATOM   1103  C CB  . PHE A 1 181 ? 109.671 140.330 132.886 1.00 23.79  ? 146 PHE A CB  1 
ATOM   1104  C CG  . PHE A 1 181 ? 110.492 139.077 133.030 1.00 23.63  ? 146 PHE A CG  1 
ATOM   1105  C CD1 . PHE A 1 181 ? 111.147 138.788 134.215 1.00 26.46  ? 146 PHE A CD1 1 
ATOM   1106  C CD2 . PHE A 1 181 ? 110.630 138.201 131.969 1.00 23.10  ? 146 PHE A CD2 1 
ATOM   1107  C CE1 . PHE A 1 181 ? 111.905 137.642 134.343 1.00 27.13  ? 146 PHE A CE1 1 
ATOM   1108  C CE2 . PHE A 1 181 ? 111.391 137.055 132.093 1.00 24.04  ? 146 PHE A CE2 1 
ATOM   1109  C CZ  . PHE A 1 181 ? 112.027 136.776 133.280 1.00 24.80  ? 146 PHE A CZ  1 
ATOM   1110  N N   . PRO A 1 182 ? 107.815 138.318 134.881 1.00 22.67  ? 147 PRO A N   1 
ATOM   1111  C CA  . PRO A 1 182 ? 107.654 137.264 133.876 1.00 21.20  ? 147 PRO A CA  1 
ATOM   1112  C C   . PRO A 1 182 ? 106.209 137.059 133.436 1.00 23.07  ? 147 PRO A C   1 
ATOM   1113  O O   . PRO A 1 182 ? 105.871 136.006 132.907 1.00 25.97  ? 147 PRO A O   1 
ATOM   1114  C CB  . PRO A 1 182 ? 108.195 136.038 134.609 1.00 23.62  ? 147 PRO A CB  1 
ATOM   1115  C CG  . PRO A 1 182 ? 107.727 136.254 136.021 1.00 23.95  ? 147 PRO A CG  1 
ATOM   1116  C CD  . PRO A 1 182 ? 107.747 137.757 136.242 1.00 25.21  ? 147 PRO A CD  1 
ATOM   1117  N N   . MET A 1 183 ? 105.328 138.032 133.645 1.00 23.19  ? 148 MET A N   1 
ATOM   1118  C CA  . MET A 1 183 ? 103.921 137.917 133.278 1.00 22.86  ? 148 MET A CA  1 
ATOM   1119  C C   . MET A 1 183 ? 103.628 138.796 132.070 1.00 23.41  ? 148 MET A C   1 
ATOM   1120  O O   . MET A 1 183 ? 102.592 139.457 131.989 1.00 26.42  ? 148 MET A O   1 
ATOM   1121  C CB  . MET A 1 183 ? 103.022 138.298 134.448 1.00 23.21  ? 148 MET A CB  1 
ATOM   1122  C CG  . MET A 1 183 ? 103.054 137.316 135.593 1.00 27.18  ? 148 MET A CG  1 
ATOM   1123  S SD  . MET A 1 183 ? 102.455 138.064 137.112 1.00 40.22  ? 148 MET A SD  1 
ATOM   1124  C CE  . MET A 1 183 ? 103.802 139.187 137.467 1.00 27.43  ? 148 MET A CE  1 
ATOM   1125  N N   . ASP A 1 184 ? 104.552 138.794 131.119 1.00 23.06  ? 149 ASP A N   1 
ATOM   1126  C CA  . ASP A 1 184 ? 104.513 139.651 129.949 1.00 21.45  ? 149 ASP A CA  1 
ATOM   1127  C C   . ASP A 1 184 ? 104.149 138.849 128.709 1.00 19.05  ? 149 ASP A C   1 
ATOM   1128  O O   . ASP A 1 184 ? 104.357 137.636 128.636 1.00 25.09  ? 149 ASP A O   1 
ATOM   1129  C CB  . ASP A 1 184 ? 105.860 140.347 129.743 1.00 22.74  ? 149 ASP A CB  1 
ATOM   1130  C CG  . ASP A 1 184 ? 107.023 139.382 129.790 1.00 24.29  ? 149 ASP A CG  1 
ATOM   1131  O OD1 . ASP A 1 184 ? 106.806 138.209 130.158 1.00 24.92  ? 149 ASP A OD1 1 
ATOM   1132  O OD2 . ASP A 1 184 ? 108.154 139.793 129.464 1.00 27.49  ? 149 ASP A OD2 1 
ATOM   1133  N N   . ALA A 1 185 ? 103.592 139.553 127.733 1.00 18.58  ? 150 ALA A N   1 
ATOM   1134  C CA  . ALA A 1 185 ? 103.319 138.995 126.421 1.00 19.32  ? 150 ALA A CA  1 
ATOM   1135  C C   . ALA A 1 185 ? 103.954 139.902 125.381 1.00 20.63  ? 150 ALA A C   1 
ATOM   1136  O O   . ALA A 1 185 ? 104.124 141.103 125.606 1.00 21.86  ? 150 ALA A O   1 
ATOM   1137  C CB  . ALA A 1 185 ? 101.814 138.860 126.162 1.00 18.37  ? 150 ALA A CB  1 
ATOM   1138  N N   . HIS A 1 186 ? 104.307 139.322 124.240 1.00 19.95  ? 151 HIS A N   1 
ATOM   1139  C CA  . HIS A 1 186 ? 105.006 140.067 123.207 1.00 20.83  ? 151 HIS A CA  1 
ATOM   1140  C C   . HIS A 1 186 ? 104.456 139.684 121.846 1.00 23.53  ? 151 HIS A C   1 
ATOM   1141  O O   . HIS A 1 186 ? 103.892 138.604 121.658 1.00 28.03  ? 151 HIS A O   1 
ATOM   1142  C CB  . HIS A 1 186 ? 106.517 139.798 123.228 1.00 23.09  ? 151 HIS A CB  1 
ATOM   1143  C CG  . HIS A 1 186 ? 107.147 139.963 124.574 1.00 30.16  ? 151 HIS A CG  1 
ATOM   1144  N ND1 . HIS A 1 186 ? 107.395 138.899 125.413 1.00 29.42  ? 151 HIS A ND1 1 
ATOM   1145  C CD2 . HIS A 1 186 ? 107.591 141.065 125.223 1.00 32.81  ? 151 HIS A CD2 1 
ATOM   1146  C CE1 . HIS A 1 186 ? 107.958 139.339 126.523 1.00 29.59  ? 151 HIS A CE1 1 
ATOM   1147  N NE2 . HIS A 1 186 ? 108.088 140.650 126.434 1.00 31.10  ? 151 HIS A NE2 1 
ATOM   1148  N N   . ALA A 1 187 ? 104.630 140.592 120.895 1.00 25.25  ? 152 ALA A N   1 
ATOM   1149  C CA  . ALA A 1 187 ? 104.314 140.342 119.495 1.00 25.95  ? 152 ALA A CA  1 
ATOM   1150  C C   . ALA A 1 187 ? 105.628 140.484 118.741 1.00 29.70  ? 152 ALA A C   1 
ATOM   1151  O O   . ALA A 1 187 ? 106.030 141.598 118.391 1.00 35.90  ? 152 ALA A O   1 
ATOM   1152  C CB  . ALA A 1 187 ? 103.253 141.308 118.977 1.00 21.36  ? 152 ALA A CB  1 
ATOM   1153  N N   . CYS A 1 188 ? 106.293 139.366 118.484 1.00 25.27  ? 153 CYS A N   1 
ATOM   1154  C CA  . CYS A 1 188 ? 107.557 139.415 117.771 1.00 24.71  ? 153 CYS A CA  1 
ATOM   1155  C C   . CYS A 1 188 ? 107.276 139.551 116.284 1.00 26.66  ? 153 CYS A C   1 
ATOM   1156  O O   . CYS A 1 188 ? 106.603 138.689 115.710 1.00 28.75  ? 153 CYS A O   1 
ATOM   1157  C CB  . CYS A 1 188 ? 108.397 138.179 118.050 1.00 28.19  ? 153 CYS A CB  1 
ATOM   1158  S SG  . CYS A 1 188 ? 109.102 138.150 119.709 1.00 71.55  ? 153 CYS A SG  1 
ATOM   1159  N N   . PRO A 1 189 ? 107.759 140.600 115.631 1.00 27.17  ? 154 PRO A N   1 
ATOM   1160  C CA  . PRO A 1 189 ? 107.434 140.816 114.224 1.00 23.32  ? 154 PRO A CA  1 
ATOM   1161  C C   . PRO A 1 189 ? 108.413 140.134 113.283 1.00 19.42  ? 154 PRO A C   1 
ATOM   1162  O O   . PRO A 1 189 ? 109.506 139.709 113.660 1.00 23.07  ? 154 PRO A O   1 
ATOM   1163  C CB  . PRO A 1 189 ? 107.524 142.341 114.088 1.00 26.45  ? 154 PRO A CB  1 
ATOM   1164  C CG  . PRO A 1 189 ? 108.591 142.716 115.056 1.00 29.55  ? 154 PRO A CG  1 
ATOM   1165  C CD  . PRO A 1 189 ? 108.511 141.731 116.202 1.00 28.47  ? 154 PRO A CD  1 
ATOM   1166  N N   . LEU A 1 190 ? 107.980 140.035 112.031 1.00 18.78  ? 155 LEU A N   1 
ATOM   1167  C CA  . LEU A 1 190 ? 108.817 139.537 110.946 1.00 22.68  ? 155 LEU A CA  1 
ATOM   1168  C C   . LEU A 1 190 ? 108.408 140.349 109.725 1.00 20.91  ? 155 LEU A C   1 
ATOM   1169  O O   . LEU A 1 190 ? 107.382 140.064 109.103 1.00 29.05  ? 155 LEU A O   1 
ATOM   1170  C CB  . LEU A 1 190 ? 108.625 138.045 110.720 1.00 22.11  ? 155 LEU A CB  1 
ATOM   1171  C CG  . LEU A 1 190 ? 109.495 137.441 109.616 1.00 15.62  ? 155 LEU A CG  1 
ATOM   1172  C CD1 . LEU A 1 190 ? 110.965 137.578 109.973 1.00 13.99  ? 155 LEU A CD1 1 
ATOM   1173  C CD2 . LEU A 1 190 ? 109.129 135.988 109.359 1.00 15.13  ? 155 LEU A CD2 1 
ATOM   1174  N N   . LYS A 1 191 ? 109.209 141.352 109.394 1.00 12.52  ? 156 LYS A N   1 
ATOM   1175  C CA  . LYS A 1 191 ? 108.899 142.265 108.310 1.00 13.03  ? 156 LYS A CA  1 
ATOM   1176  C C   . LYS A 1 191 ? 109.874 142.035 107.170 1.00 14.27  ? 156 LYS A C   1 
ATOM   1177  O O   . LYS A 1 191 ? 111.064 141.804 107.397 1.00 18.26  ? 156 LYS A O   1 
ATOM   1178  C CB  . LYS A 1 191 ? 108.983 143.714 108.788 1.00 15.72  ? 156 LYS A CB  1 
ATOM   1179  C CG  . LYS A 1 191 ? 108.026 144.035 109.919 1.00 20.88  ? 156 LYS A CG  1 
ATOM   1180  C CD  . LYS A 1 191 ? 108.300 145.403 110.512 1.00 23.05  ? 156 LYS A CD  1 
ATOM   1181  C CE  . LYS A 1 191 ? 107.299 145.733 111.604 1.00 22.69  ? 156 LYS A CE  1 
ATOM   1182  N NZ  . LYS A 1 191 ? 107.627 147.012 112.290 1.00 19.14  ? 156 LYS A NZ  1 
ATOM   1183  N N   . PHE A 1 192 ? 109.366 142.092 105.945 1.00 13.91  ? 157 PHE A N   1 
ATOM   1184  C CA  . PHE A 1 192 ? 110.232 141.979 104.787 1.00 14.70  ? 157 PHE A CA  1 
ATOM   1185  C C   . PHE A 1 192 ? 109.683 142.821 103.647 1.00 17.52  ? 157 PHE A C   1 
ATOM   1186  O O   . PHE A 1 192 ? 108.542 143.287 103.675 1.00 21.17  ? 157 PHE A O   1 
ATOM   1187  C CB  . PHE A 1 192 ? 110.414 140.508 104.388 1.00 15.79  ? 157 PHE A CB  1 
ATOM   1188  C CG  . PHE A 1 192 ? 109.135 139.789 104.073 1.00 14.95  ? 157 PHE A CG  1 
ATOM   1189  C CD1 . PHE A 1 192 ? 108.625 139.776 102.789 1.00 15.67  ? 157 PHE A CD1 1 
ATOM   1190  C CD2 . PHE A 1 192 ? 108.454 139.104 105.065 1.00 13.30  ? 157 PHE A CD2 1 
ATOM   1191  C CE1 . PHE A 1 192 ? 107.454 139.105 102.503 1.00 16.01  ? 157 PHE A CE1 1 
ATOM   1192  C CE2 . PHE A 1 192 ? 107.286 138.434 104.787 1.00 13.69  ? 157 PHE A CE2 1 
ATOM   1193  C CZ  . PHE A 1 192 ? 106.785 138.432 103.504 1.00 14.75  ? 157 PHE A CZ  1 
ATOM   1194  N N   . GLY A 1 193 ? 110.522 143.008 102.639 1.00 19.23  ? 158 GLY A N   1 
ATOM   1195  C CA  . GLY A 1 193 ? 110.180 143.831 101.498 1.00 20.31  ? 158 GLY A CA  1 
ATOM   1196  C C   . GLY A 1 193 ? 111.391 143.989 100.609 1.00 22.32  ? 158 GLY A C   1 
ATOM   1197  O O   . GLY A 1 193 ? 112.449 143.403 100.850 1.00 26.39  ? 158 GLY A O   1 
ATOM   1198  N N   . SER A 1 194 ? 111.223 144.805 99.574  1.00 19.95  ? 159 SER A N   1 
ATOM   1199  C CA  . SER A 1 194 ? 112.308 145.030 98.633  1.00 23.96  ? 159 SER A CA  1 
ATOM   1200  C C   . SER A 1 194 ? 113.257 146.070 99.207  1.00 28.47  ? 159 SER A C   1 
ATOM   1201  O O   . SER A 1 194 ? 112.827 147.152 99.618  1.00 36.56  ? 159 SER A O   1 
ATOM   1202  C CB  . SER A 1 194 ? 111.768 145.487 97.281  1.00 31.94  ? 159 SER A CB  1 
ATOM   1203  O OG  . SER A 1 194 ? 112.828 145.723 96.371  1.00 34.03  ? 159 SER A OG  1 
ATOM   1204  N N   . TYR A 1 195 ? 114.549 145.744 99.235  1.00 27.31  ? 160 TYR A N   1 
ATOM   1205  C CA  . TYR A 1 195 ? 115.531 146.702 99.732  1.00 24.27  ? 160 TYR A CA  1 
ATOM   1206  C C   . TYR A 1 195 ? 115.649 147.907 98.810  1.00 26.00  ? 160 TYR A C   1 
ATOM   1207  O O   . TYR A 1 195 ? 115.765 149.046 99.278  1.00 28.23  ? 160 TYR A O   1 
ATOM   1208  C CB  . TYR A 1 195 ? 116.891 146.031 99.909  1.00 23.11  ? 160 TYR A CB  1 
ATOM   1209  C CG  . TYR A 1 195 ? 117.855 146.890 100.687 1.00 23.19  ? 160 TYR A CG  1 
ATOM   1210  C CD1 . TYR A 1 195 ? 117.841 146.889 102.072 1.00 23.05  ? 160 TYR A CD1 1 
ATOM   1211  C CD2 . TYR A 1 195 ? 118.758 147.723 100.042 1.00 23.63  ? 160 TYR A CD2 1 
ATOM   1212  C CE1 . TYR A 1 195 ? 118.707 147.676 102.794 1.00 22.39  ? 160 TYR A CE1 1 
ATOM   1213  C CE2 . TYR A 1 195 ? 119.628 148.518 100.757 1.00 21.39  ? 160 TYR A CE2 1 
ATOM   1214  C CZ  . TYR A 1 195 ? 119.596 148.489 102.134 1.00 24.50  ? 160 TYR A CZ  1 
ATOM   1215  O OH  . TYR A 1 195 ? 120.457 149.275 102.859 1.00 33.00  ? 160 TYR A OH  1 
ATOM   1216  N N   . ALA A 1 196 ? 115.623 147.679 97.498  1.00 27.34  ? 161 ALA A N   1 
ATOM   1217  C CA  . ALA A 1 196 ? 115.983 148.700 96.529  1.00 32.01  ? 161 ALA A CA  1 
ATOM   1218  C C   . ALA A 1 196 ? 114.808 149.260 95.744  1.00 37.51  ? 161 ALA A C   1 
ATOM   1219  O O   . ALA A 1 196 ? 114.898 150.393 95.264  1.00 39.59  ? 161 ALA A O   1 
ATOM   1220  C CB  . ALA A 1 196 ? 117.022 148.150 95.540  1.00 31.08  ? 161 ALA A CB  1 
ATOM   1221  N N   . TYR A 1 197 ? 113.713 148.517 95.610  1.00 37.28  ? 162 TYR A N   1 
ATOM   1222  C CA  . TYR A 1 197 ? 112.629 148.887 94.709  1.00 41.57  ? 162 TYR A CA  1 
ATOM   1223  C C   . TYR A 1 197 ? 111.494 149.473 95.537  1.00 39.75  ? 162 TYR A C   1 
ATOM   1224  O O   . TYR A 1 197 ? 110.978 148.813 96.445  1.00 38.07  ? 162 TYR A O   1 
ATOM   1225  C CB  . TYR A 1 197 ? 112.154 147.673 93.913  1.00 40.36  ? 162 TYR A CB  1 
ATOM   1226  C CG  . TYR A 1 197 ? 113.218 147.093 93.012  1.00 37.78  ? 162 TYR A CG  1 
ATOM   1227  C CD1 . TYR A 1 197 ? 113.417 147.584 91.731  1.00 41.46  ? 162 TYR A CD1 1 
ATOM   1228  C CD2 . TYR A 1 197 ? 114.036 146.062 93.452  1.00 33.58  ? 162 TYR A CD2 1 
ATOM   1229  C CE1 . TYR A 1 197 ? 114.394 147.058 90.910  1.00 43.27  ? 162 TYR A CE1 1 
ATOM   1230  C CE2 . TYR A 1 197 ? 115.013 145.529 92.640  1.00 34.29  ? 162 TYR A CE2 1 
ATOM   1231  C CZ  . TYR A 1 197 ? 115.189 146.030 91.370  1.00 37.86  ? 162 TYR A CZ  1 
ATOM   1232  O OH  . TYR A 1 197 ? 116.163 145.500 90.557  1.00 39.47  ? 162 TYR A OH  1 
ATOM   1233  N N   . THR A 1 198 ? 111.087 150.692 95.192  1.00 43.60  ? 163 THR A N   1 
ATOM   1234  C CA  . THR A 1 198 ? 109.972 151.359 95.844  1.00 46.70  ? 163 THR A CA  1 
ATOM   1235  C C   . THR A 1 198 ? 108.636 150.769 95.400  1.00 47.20  ? 163 THR A C   1 
ATOM   1236  O O   . THR A 1 198 ? 108.550 149.976 94.458  1.00 46.98  ? 163 THR A O   1 
ATOM   1237  C CB  . THR A 1 198 ? 110.003 152.858 95.547  1.00 47.45  ? 163 THR A CB  1 
ATOM   1238  O OG1 . THR A 1 198 ? 109.900 153.070 94.134  1.00 51.80  ? 163 THR A OG1 1 
ATOM   1239  C CG2 . THR A 1 198 ? 111.297 153.473 96.051  1.00 46.00  ? 163 THR A CG2 1 
ATOM   1240  N N   . ARG A 1 199 ? 107.578 151.168 96.116  1.00 48.12  ? 164 ARG A N   1 
ATOM   1241  C CA  . ARG A 1 199 ? 106.248 150.629 95.862  1.00 47.79  ? 164 ARG A CA  1 
ATOM   1242  C C   . ARG A 1 199 ? 105.766 150.941 94.455  1.00 48.16  ? 164 ARG A C   1 
ATOM   1243  O O   . ARG A 1 199 ? 104.891 150.238 93.939  1.00 46.21  ? 164 ARG A O   1 
ATOM   1244  C CB  . ARG A 1 199 ? 105.249 151.181 96.880  1.00 45.12  ? 164 ARG A CB  1 
ATOM   1245  C CG  . ARG A 1 199 ? 105.053 152.685 96.799  1.00 50.66  ? 164 ARG A CG  1 
ATOM   1246  C CD  . ARG A 1 199 ? 103.904 153.140 97.682  1.00 57.68  ? 164 ARG A CD  1 
ATOM   1247  N NE  . ARG A 1 199 ? 103.556 154.536 97.449  1.00 63.76  ? 164 ARG A NE  1 
ATOM   1248  C CZ  . ARG A 1 199 ? 102.546 155.163 98.035  1.00 60.77  ? 164 ARG A CZ  1 
ATOM   1249  N NH1 . ARG A 1 199 ? 101.755 154.545 98.896  1.00 47.77  ? 164 ARG A NH1 1 
ATOM   1250  N NH2 . ARG A 1 199 ? 102.324 156.443 97.751  1.00 68.11  ? 164 ARG A NH2 1 
ATOM   1251  N N   . ALA A 1 200 ? 106.311 151.982 93.825  1.00 51.95  ? 165 ALA A N   1 
ATOM   1252  C CA  . ALA A 1 200 ? 105.986 152.275 92.438  1.00 56.34  ? 165 ALA A CA  1 
ATOM   1253  C C   . ALA A 1 200 ? 106.553 151.235 91.483  1.00 59.60  ? 165 ALA A C   1 
ATOM   1254  O O   . ALA A 1 200 ? 106.184 151.234 90.304  1.00 63.08  ? 165 ALA A O   1 
ATOM   1255  C CB  . ALA A 1 200 ? 106.499 153.665 92.059  1.00 50.48  ? 165 ALA A CB  1 
ATOM   1256  N N   . GLU A 1 201 ? 107.436 150.362 91.962  1.00 54.86  ? 166 GLU A N   1 
ATOM   1257  C CA  . GLU A 1 201 ? 108.081 149.353 91.134  1.00 51.55  ? 166 GLU A CA  1 
ATOM   1258  C C   . GLU A 1 201 ? 107.722 147.936 91.552  1.00 50.36  ? 166 GLU A C   1 
ATOM   1259  O O   . GLU A 1 201 ? 107.320 147.132 90.704  1.00 56.50  ? 166 GLU A O   1 
ATOM   1260  C CB  . GLU A 1 201 ? 109.604 149.549 91.174  1.00 50.55  ? 166 GLU A CB  1 
ATOM   1261  C CG  . GLU A 1 201 ? 110.065 150.850 90.534  1.00 61.94  ? 166 GLU A CG  1 
ATOM   1262  C CD  . GLU A 1 201 ? 111.553 151.094 90.703  1.00 74.66  ? 166 GLU A CD  1 
ATOM   1263  O OE1 . GLU A 1 201 ? 112.128 150.607 91.699  1.00 69.76  ? 166 GLU A OE1 1 
ATOM   1264  O OE2 . GLU A 1 201 ? 112.145 151.778 89.842  1.00 85.11  ? 166 GLU A OE2 1 
ATOM   1265  N N   . VAL A 1 202 ? 107.867 147.596 92.831  1.00 47.66  ? 167 VAL A N   1 
ATOM   1266  C CA  . VAL A 1 202 ? 107.568 146.256 93.325  1.00 47.33  ? 167 VAL A CA  1 
ATOM   1267  C C   . VAL A 1 202 ? 106.621 146.360 94.513  1.00 46.34  ? 167 VAL A C   1 
ATOM   1268  O O   . VAL A 1 202 ? 106.924 147.050 95.492  1.00 46.84  ? 167 VAL A O   1 
ATOM   1269  C CB  . VAL A 1 202 ? 108.852 145.503 93.723  1.00 38.75  ? 167 VAL A CB  1 
ATOM   1270  C CG1 . VAL A 1 202 ? 108.513 144.261 94.516  1.00 28.98  ? 167 VAL A CG1 1 
ATOM   1271  C CG2 . VAL A 1 202 ? 109.661 145.146 92.486  1.00 45.07  ? 167 VAL A CG2 1 
ATOM   1272  N N   . VAL A 1 203 ? 105.484 145.667 94.434  1.00 45.74  ? 168 VAL A N   1 
ATOM   1273  C CA  . VAL A 1 203 ? 104.546 145.555 95.546  1.00 41.71  ? 168 VAL A CA  1 
ATOM   1274  C C   . VAL A 1 203 ? 104.419 144.086 95.924  1.00 37.28  ? 168 VAL A C   1 
ATOM   1275  O O   . VAL A 1 203 ? 104.410 143.211 95.052  1.00 41.00  ? 168 VAL A O   1 
ATOM   1276  C CB  . VAL A 1 203 ? 103.162 146.149 95.202  1.00 40.73  ? 168 VAL A CB  1 
ATOM   1277  C CG1 . VAL A 1 203 ? 103.249 147.658 95.063  1.00 45.04  ? 168 VAL A CG1 1 
ATOM   1278  C CG2 . VAL A 1 203 ? 102.608 145.525 93.932  1.00 40.17  ? 168 VAL A CG2 1 
ATOM   1279  N N   . TYR A 1 204 ? 104.338 143.816 97.221  1.00 30.15  ? 169 TYR A N   1 
ATOM   1280  C CA  . TYR A 1 204 ? 104.132 142.464 97.716  1.00 28.25  ? 169 TYR A CA  1 
ATOM   1281  C C   . TYR A 1 204 ? 102.701 142.256 98.202  1.00 34.09  ? 169 TYR A C   1 
ATOM   1282  O O   . TYR A 1 204 ? 102.030 143.195 98.636  1.00 40.27  ? 169 TYR A O   1 
ATOM   1283  C CB  . TYR A 1 204 ? 105.114 142.147 98.843  1.00 26.75  ? 169 TYR A CB  1 
ATOM   1284  C CG  . TYR A 1 204 ? 106.546 141.977 98.390  1.00 25.48  ? 169 TYR A CG  1 
ATOM   1285  C CD1 . TYR A 1 204 ? 107.337 143.076 98.092  1.00 25.05  ? 169 TYR A CD1 1 
ATOM   1286  C CD2 . TYR A 1 204 ? 107.105 140.714 98.259  1.00 23.96  ? 169 TYR A CD2 1 
ATOM   1287  C CE1 . TYR A 1 204 ? 108.644 142.922 97.679  1.00 23.26  ? 169 TYR A CE1 1 
ATOM   1288  C CE2 . TYR A 1 204 ? 108.410 140.550 97.847  1.00 21.50  ? 169 TYR A CE2 1 
ATOM   1289  C CZ  . TYR A 1 204 ? 109.175 141.657 97.556  1.00 23.59  ? 169 TYR A CZ  1 
ATOM   1290  O OH  . TYR A 1 204 ? 110.478 141.499 97.145  1.00 28.00  ? 169 TYR A OH  1 
ATOM   1291  N N   . GLU A 1 205 ? 102.252 141.000 98.148  1.00 36.15  ? 170 GLU A N   1 
ATOM   1292  C CA  . GLU A 1 205 ? 100.935 140.591 98.625  1.00 32.63  ? 170 GLU A CA  1 
ATOM   1293  C C   . GLU A 1 205 ? 101.009 139.142 99.087  1.00 29.11  ? 170 GLU A C   1 
ATOM   1294  O O   . GLU A 1 205 ? 101.959 138.420 98.777  1.00 32.61  ? 170 GLU A O   1 
ATOM   1295  C CB  . GLU A 1 205 ? 99.830  140.734 97.567  1.00 36.89  ? 170 GLU A CB  1 
ATOM   1296  C CG  . GLU A 1 205 ? 99.637  142.125 96.991  1.00 49.23  ? 170 GLU A CG  1 
ATOM   1297  C CD  . GLU A 1 205 ? 98.458  142.197 96.042  1.00 62.74  ? 170 GLU A CD  1 
ATOM   1298  O OE1 . GLU A 1 205 ? 97.734  141.186 95.918  1.00 60.62  ? 170 GLU A OE1 1 
ATOM   1299  O OE2 . GLU A 1 205 ? 98.252  143.262 95.421  1.00 68.28  ? 170 GLU A OE2 1 
ATOM   1300  N N   . TRP A 1 206 ? 100.004 138.731 99.855  1.00 27.31  ? 171 TRP A N   1 
ATOM   1301  C CA  . TRP A 1 206 ? 99.881  137.350 100.308 1.00 33.01  ? 171 TRP A CA  1 
ATOM   1302  C C   . TRP A 1 206 ? 99.143  136.519 99.264  1.00 40.36  ? 171 TRP A C   1 
ATOM   1303  O O   . TRP A 1 206 ? 98.185  136.989 98.644  1.00 45.18  ? 171 TRP A O   1 
ATOM   1304  C CB  . TRP A 1 206 ? 99.159  137.297 101.654 1.00 27.48  ? 171 TRP A CB  1 
ATOM   1305  C CG  . TRP A 1 206 ? 99.902  138.017 102.738 1.00 26.58  ? 171 TRP A CG  1 
ATOM   1306  C CD1 . TRP A 1 206 ? 99.556  139.199 103.318 1.00 33.13  ? 171 TRP A CD1 1 
ATOM   1307  C CD2 . TRP A 1 206 ? 101.098 137.583 103.397 1.00 25.77  ? 171 TRP A CD2 1 
ATOM   1308  N NE1 . TRP A 1 206 ? 100.474 139.543 104.278 1.00 33.73  ? 171 TRP A NE1 1 
ATOM   1309  C CE2 . TRP A 1 206 ? 101.432 138.566 104.345 1.00 27.35  ? 171 TRP A CE2 1 
ATOM   1310  C CE3 . TRP A 1 206 ? 101.925 136.465 103.268 1.00 27.81  ? 171 TRP A CE3 1 
ATOM   1311  C CZ2 . TRP A 1 206 ? 102.552 138.462 105.166 1.00 24.37  ? 171 TRP A CZ2 1 
ATOM   1312  C CZ3 . TRP A 1 206 ? 103.038 136.366 104.081 1.00 23.10  ? 171 TRP A CZ3 1 
ATOM   1313  C CH2 . TRP A 1 206 ? 103.340 137.356 105.019 1.00 20.93  ? 171 TRP A CH2 1 
ATOM   1314  N N   . THR A 1 207 ? 99.608  135.280 99.067  1.00 40.00  ? 172 THR A N   1 
ATOM   1315  C CA  . THR A 1 207 ? 99.029  134.416 98.040  1.00 40.31  ? 172 THR A CA  1 
ATOM   1316  C C   . THR A 1 207 ? 97.543  134.171 98.274  1.00 46.19  ? 172 THR A C   1 
ATOM   1317  O O   . THR A 1 207 ? 96.743  134.217 97.333  1.00 52.15  ? 172 THR A O   1 
ATOM   1318  C CB  . THR A 1 207 ? 99.779  133.086 97.997  1.00 37.83  ? 172 THR A CB  1 
ATOM   1319  O OG1 . THR A 1 207 ? 101.186 133.333 97.898  1.00 36.67  ? 172 THR A OG1 1 
ATOM   1320  C CG2 . THR A 1 207 ? 99.331  132.260 96.804  1.00 37.67  ? 172 THR A CG2 1 
ATOM   1321  N N   . ARG A 1 208 ? 97.153  133.912 99.520  1.00 49.30  ? 173 ARG A N   1 
ATOM   1322  C CA  . ARG A 1 208 ? 95.746  133.739 99.858  1.00 55.24  ? 173 ARG A CA  1 
ATOM   1323  C C   . ARG A 1 208 ? 95.383  134.655 101.017 1.00 54.38  ? 173 ARG A C   1 
ATOM   1324  O O   . ARG A 1 208 ? 96.127  135.593 101.320 1.00 53.53  ? 173 ARG A O   1 
ATOM   1325  C CB  . ARG A 1 208 ? 95.431  132.282 100.206 1.00 52.68  ? 173 ARG A CB  1 
ATOM   1326  C CG  . ARG A 1 208 ? 96.239  131.706 101.358 1.00 53.07  ? 173 ARG A CG  1 
ATOM   1327  C CD  . ARG A 1 208 ? 96.183  130.183 101.356 1.00 56.86  ? 173 ARG A CD  1 
ATOM   1328  N NE  . ARG A 1 208 ? 96.938  129.579 100.265 1.00 56.25  ? 173 ARG A NE  1 
ATOM   1329  C CZ  . ARG A 1 208 ? 98.236  129.311 100.312 1.00 51.35  ? 173 ARG A CZ  1 
ATOM   1330  N NH1 . ARG A 1 208 ? 98.959  129.578 101.387 1.00 50.15  ? 173 ARG A NH1 1 
ATOM   1331  N NH2 . ARG A 1 208 ? 98.822  128.757 99.254  1.00 46.05  ? 173 ARG A NH2 1 
ATOM   1332  N N   . GLU A 1 209 ? 94.223  134.422 101.625 1.00 57.40  ? 174 GLU A N   1 
ATOM   1333  C CA  . GLU A 1 209 ? 93.797  135.209 102.773 1.00 57.28  ? 174 GLU A CA  1 
ATOM   1334  C C   . GLU A 1 209 ? 94.946  135.334 103.773 1.00 49.71  ? 174 GLU A C   1 
ATOM   1335  O O   . GLU A 1 209 ? 95.657  134.351 104.023 1.00 46.30  ? 174 GLU A O   1 
ATOM   1336  C CB  . GLU A 1 209 ? 92.578  134.569 103.445 1.00 61.38  ? 174 GLU A CB  1 
ATOM   1337  C CG  . GLU A 1 209 ? 91.324  134.519 102.579 1.00 67.76  ? 174 GLU A CG  1 
ATOM   1338  C CD  . GLU A 1 209 ? 91.301  133.336 101.632 1.00 76.78  ? 174 GLU A CD  1 
ATOM   1339  O OE1 . GLU A 1 209 ? 92.266  132.543 101.639 1.00 73.59  ? 174 GLU A OE1 1 
ATOM   1340  O OE2 . GLU A 1 209 ? 90.314  133.197 100.880 1.00 82.23  ? 174 GLU A OE2 1 
ATOM   1341  N N   . PRO A 1 210 ? 95.172  136.520 104.345 1.00 47.09  ? 175 PRO A N   1 
ATOM   1342  C CA  . PRO A 1 210 ? 96.337  136.700 105.227 1.00 41.74  ? 175 PRO A CA  1 
ATOM   1343  C C   . PRO A 1 210 ? 96.395  135.712 106.376 1.00 39.88  ? 175 PRO A C   1 
ATOM   1344  O O   . PRO A 1 210 ? 97.493  135.295 106.762 1.00 36.32  ? 175 PRO A O   1 
ATOM   1345  C CB  . PRO A 1 210 ? 96.167  138.139 105.730 1.00 37.90  ? 175 PRO A CB  1 
ATOM   1346  C CG  . PRO A 1 210 ? 95.394  138.818 104.651 1.00 38.18  ? 175 PRO A CG  1 
ATOM   1347  C CD  . PRO A 1 210 ? 94.441  137.780 104.130 1.00 45.88  ? 175 PRO A CD  1 
ATOM   1348  N N   . ALA A 1 211 ? 95.249  135.310 106.928 1.00 43.72  ? 176 ALA A N   1 
ATOM   1349  C CA  . ALA A 1 211 ? 95.268  134.345 108.021 1.00 49.20  ? 176 ALA A CA  1 
ATOM   1350  C C   . ALA A 1 211 ? 95.759  132.979 107.559 1.00 50.82  ? 176 ALA A C   1 
ATOM   1351  O O   . ALA A 1 211 ? 96.367  132.243 108.344 1.00 46.24  ? 176 ALA A O   1 
ATOM   1352  C CB  . ALA A 1 211 ? 93.877  134.228 108.643 1.00 49.03  ? 176 ALA A CB  1 
ATOM   1353  N N   . ARG A 1 212 ? 95.511  132.625 106.299 1.00 51.07  ? 177 ARG A N   1 
ATOM   1354  C CA  . ARG A 1 212 ? 95.894  131.328 105.759 1.00 47.24  ? 177 ARG A CA  1 
ATOM   1355  C C   . ARG A 1 212 ? 97.191  131.378 104.960 1.00 43.89  ? 177 ARG A C   1 
ATOM   1356  O O   . ARG A 1 212 ? 97.535  130.395 104.297 1.00 46.11  ? 177 ARG A O   1 
ATOM   1357  C CB  . ARG A 1 212 ? 94.767  130.762 104.894 1.00 55.34  ? 177 ARG A CB  1 
ATOM   1358  C CG  . ARG A 1 212 ? 93.417  130.721 105.594 1.00 63.04  ? 177 ARG A CG  1 
ATOM   1359  C CD  . ARG A 1 212 ? 92.395  129.871 104.845 1.00 78.52  ? 177 ARG A CD  1 
ATOM   1360  N NE  . ARG A 1 212 ? 92.266  130.233 103.438 1.00 83.15  ? 177 ARG A NE  1 
ATOM   1361  C CZ  . ARG A 1 212 ? 92.850  129.583 102.440 1.00 79.22  ? 177 ARG A CZ  1 
ATOM   1362  N NH1 . ARG A 1 212 ? 93.606  128.519 102.657 1.00 69.53  ? 177 ARG A NH1 1 
ATOM   1363  N NH2 . ARG A 1 212 ? 92.667  130.008 101.193 1.00 71.61  ? 177 ARG A NH2 1 
ATOM   1364  N N   . SER A 1 213 ? 97.916  132.496 105.002 1.00 43.25  ? 178 SER A N   1 
ATOM   1365  C CA  . SER A 1 213 ? 99.157  132.621 104.248 1.00 36.74  ? 178 SER A CA  1 
ATOM   1366  C C   . SER A 1 213 ? 100.391 132.280 105.073 1.00 26.08  ? 178 SER A C   1 
ATOM   1367  O O   . SER A 1 213 ? 101.416 131.890 104.503 1.00 26.05  ? 178 SER A O   1 
ATOM   1368  C CB  . SER A 1 213 ? 99.294  134.037 103.684 1.00 40.56  ? 178 SER A CB  1 
ATOM   1369  O OG  . SER A 1 213 ? 98.223  134.340 102.809 1.00 46.13  ? 178 SER A OG  1 
ATOM   1370  N N   . VAL A 1 214 ? 100.324 132.418 106.392 1.00 23.30  ? 179 VAL A N   1 
ATOM   1371  C CA  . VAL A 1 214 ? 101.397 131.997 107.284 1.00 20.44  ? 179 VAL A CA  1 
ATOM   1372  C C   . VAL A 1 214 ? 100.926 130.736 107.991 1.00 27.91  ? 179 VAL A C   1 
ATOM   1373  O O   . VAL A 1 214 ? 99.990  130.778 108.798 1.00 31.72  ? 179 VAL A O   1 
ATOM   1374  C CB  . VAL A 1 214 ? 101.771 133.091 108.291 1.00 21.35  ? 179 VAL A CB  1 
ATOM   1375  C CG1 . VAL A 1 214 ? 102.877 132.604 109.209 1.00 20.46  ? 179 VAL A CG1 1 
ATOM   1376  C CG2 . VAL A 1 214 ? 102.200 134.351 107.566 1.00 24.82  ? 179 VAL A CG2 1 
ATOM   1377  N N   . VAL A 1 215 ? 101.571 129.611 107.695 1.00 29.80  ? 180 VAL A N   1 
ATOM   1378  C CA  . VAL A 1 215 ? 101.176 128.313 108.223 1.00 28.36  ? 180 VAL A CA  1 
ATOM   1379  C C   . VAL A 1 215 ? 102.292 127.797 109.117 1.00 26.26  ? 180 VAL A C   1 
ATOM   1380  O O   . VAL A 1 215 ? 103.462 127.791 108.720 1.00 25.11  ? 180 VAL A O   1 
ATOM   1381  C CB  . VAL A 1 215 ? 100.874 127.309 107.095 1.00 26.11  ? 180 VAL A CB  1 
ATOM   1382  C CG1 . VAL A 1 215 ? 100.520 125.950 107.676 1.00 27.52  ? 180 VAL A CG1 1 
ATOM   1383  C CG2 . VAL A 1 215 ? 99.750  127.825 106.212 1.00 28.13  ? 180 VAL A CG2 1 
ATOM   1384  N N   . VAL A 1 216 ? 101.927 127.364 110.318 1.00 26.68  ? 181 VAL A N   1 
ATOM   1385  C CA  . VAL A 1 216 ? 102.862 126.795 111.279 1.00 29.51  ? 181 VAL A CA  1 
ATOM   1386  C C   . VAL A 1 216 ? 102.638 125.291 111.318 1.00 38.55  ? 181 VAL A C   1 
ATOM   1387  O O   . VAL A 1 216 ? 101.492 124.827 111.360 1.00 45.37  ? 181 VAL A O   1 
ATOM   1388  C CB  . VAL A 1 216 ? 102.688 127.421 112.676 1.00 23.95  ? 181 VAL A CB  1 
ATOM   1389  C CG1 . VAL A 1 216 ? 103.661 126.802 113.667 1.00 24.32  ? 181 VAL A CG1 1 
ATOM   1390  C CG2 . VAL A 1 216 ? 102.876 128.927 112.606 1.00 20.63  ? 181 VAL A CG2 1 
ATOM   1391  N N   . ALA A 1 217 ? 103.729 124.530 111.300 1.00 35.11  ? 182 ALA A N   1 
ATOM   1392  C CA  . ALA A 1 217 ? 103.617 123.085 111.424 1.00 38.70  ? 182 ALA A CA  1 
ATOM   1393  C C   . ALA A 1 217 ? 103.059 122.721 112.795 1.00 51.88  ? 182 ALA A C   1 
ATOM   1394  O O   . ALA A 1 217 ? 103.310 123.403 113.793 1.00 52.90  ? 182 ALA A O   1 
ATOM   1395  C CB  . ALA A 1 217 ? 104.978 122.423 111.210 1.00 32.94  ? 182 ALA A CB  1 
ATOM   1396  N N   . GLU A 1 218 ? 102.281 121.636 112.836 1.00 55.77  ? 183 GLU A N   1 
ATOM   1397  C CA  . GLU A 1 218 ? 101.645 121.237 114.088 1.00 58.43  ? 183 GLU A CA  1 
ATOM   1398  C C   . GLU A 1 218 ? 102.681 120.915 115.157 1.00 52.07  ? 183 GLU A C   1 
ATOM   1399  O O   . GLU A 1 218 ? 102.477 121.214 116.339 1.00 48.69  ? 183 GLU A O   1 
ATOM   1400  C CB  . GLU A 1 218 ? 100.727 120.038 113.850 1.00 67.29  ? 183 GLU A CB  1 
ATOM   1401  C CG  . GLU A 1 218 ? 99.512  120.351 112.991 1.00 73.51  ? 183 GLU A CG  1 
ATOM   1402  C CD  . GLU A 1 218 ? 98.712  119.113 112.635 1.00 84.23  ? 183 GLU A CD  1 
ATOM   1403  O OE1 . GLU A 1 218 ? 99.179  117.994 112.934 1.00 86.11  ? 183 GLU A OE1 1 
ATOM   1404  O OE2 . GLU A 1 218 ? 97.616  119.260 112.055 1.00 85.06  ? 183 GLU A OE2 1 
ATOM   1405  N N   . ASP A 1 219 ? 103.802 120.315 114.762 1.00 54.98  ? 184 ASP A N   1 
ATOM   1406  C CA  . ASP A 1 219 ? 104.902 120.045 115.678 1.00 56.82  ? 184 ASP A CA  1 
ATOM   1407  C C   . ASP A 1 219 ? 105.996 121.099 115.567 1.00 54.62  ? 184 ASP A C   1 
ATOM   1408  O O   . ASP A 1 219 ? 107.175 120.799 115.783 1.00 54.45  ? 184 ASP A O   1 
ATOM   1409  C CB  . ASP A 1 219 ? 105.478 118.654 115.414 1.00 62.44  ? 184 ASP A CB  1 
ATOM   1410  C CG  . ASP A 1 219 ? 104.433 117.561 115.512 1.00 68.65  ? 184 ASP A CG  1 
ATOM   1411  O OD1 . ASP A 1 219 ? 103.227 117.885 115.498 1.00 65.59  ? 184 ASP A OD1 1 
ATOM   1412  O OD2 . ASP A 1 219 ? 104.817 116.375 115.596 1.00 75.24  ? 184 ASP A OD2 1 
ATOM   1413  N N   . GLY A 1 220 ? 105.625 122.333 115.238 1.00 49.77  ? 185 GLY A N   1 
ATOM   1414  C CA  . GLY A 1 220 ? 106.608 123.368 115.001 1.00 41.69  ? 185 GLY A CA  1 
ATOM   1415  C C   . GLY A 1 220 ? 107.050 124.150 116.218 1.00 36.72  ? 185 GLY A C   1 
ATOM   1416  O O   . GLY A 1 220 ? 108.172 124.664 116.244 1.00 35.98  ? 185 GLY A O   1 
ATOM   1417  N N   . SER A 1 221 ? 106.193 124.260 117.229 1.00 35.61  ? 186 SER A N   1 
ATOM   1418  C CA  . SER A 1 221 ? 106.525 125.088 118.383 1.00 34.27  ? 186 SER A CA  1 
ATOM   1419  C C   . SER A 1 221 ? 107.703 124.470 119.125 1.00 32.70  ? 186 SER A C   1 
ATOM   1420  O O   . SER A 1 221 ? 107.566 123.425 119.769 1.00 31.75  ? 186 SER A O   1 
ATOM   1421  C CB  . SER A 1 221 ? 105.313 125.230 119.298 1.00 38.91  ? 186 SER A CB  1 
ATOM   1422  O OG  . SER A 1 221 ? 105.643 125.954 120.470 1.00 31.96  ? 186 SER A OG  1 
ATOM   1423  N N   . ARG A 1 222 ? 108.861 125.116 119.036 1.00 31.26  ? 187 ARG A N   1 
ATOM   1424  C CA  . ARG A 1 222 ? 110.071 124.691 119.727 1.00 31.10  ? 187 ARG A CA  1 
ATOM   1425  C C   . ARG A 1 222 ? 110.419 125.663 120.849 1.00 28.70  ? 187 ARG A C   1 
ATOM   1426  O O   . ARG A 1 222 ? 111.582 126.007 121.064 1.00 25.66  ? 187 ARG A O   1 
ATOM   1427  C CB  . ARG A 1 222 ? 111.225 124.520 118.743 1.00 26.18  ? 187 ARG A CB  1 
ATOM   1428  C CG  . ARG A 1 222 ? 111.290 123.098 118.200 1.00 27.53  ? 187 ARG A CG  1 
ATOM   1429  C CD  . ARG A 1 222 ? 112.004 122.988 116.868 1.00 28.49  ? 187 ARG A CD  1 
ATOM   1430  N NE  . ARG A 1 222 ? 111.758 121.686 116.258 1.00 33.77  ? 187 ARG A NE  1 
ATOM   1431  C CZ  . ARG A 1 222 ? 112.190 121.318 115.060 1.00 37.98  ? 187 ARG A CZ  1 
ATOM   1432  N NH1 . ARG A 1 222 ? 112.944 122.115 114.321 1.00 39.47  ? 187 ARG A NH1 1 
ATOM   1433  N NH2 . ARG A 1 222 ? 111.865 120.116 114.594 1.00 39.45  ? 187 ARG A NH2 1 
ATOM   1434  N N   . LEU A 1 223 ? 109.398 126.111 121.572 1.00 29.10  ? 188 LEU A N   1 
ATOM   1435  C CA  . LEU A 1 223 ? 109.528 127.149 122.585 1.00 29.20  ? 188 LEU A CA  1 
ATOM   1436  C C   . LEU A 1 223 ? 109.481 126.523 123.970 1.00 30.13  ? 188 LEU A C   1 
ATOM   1437  O O   . LEU A 1 223 ? 108.601 125.705 124.261 1.00 27.99  ? 188 LEU A O   1 
ATOM   1438  C CB  . LEU A 1 223 ? 108.420 128.193 122.438 1.00 27.34  ? 188 LEU A CB  1 
ATOM   1439  C CG  . LEU A 1 223 ? 108.343 128.897 121.084 1.00 22.29  ? 188 LEU A CG  1 
ATOM   1440  C CD1 . LEU A 1 223 ? 107.077 129.725 120.977 1.00 25.16  ? 188 LEU A CD1 1 
ATOM   1441  C CD2 . LEU A 1 223 ? 109.566 129.768 120.885 1.00 23.02  ? 188 LEU A CD2 1 
ATOM   1442  N N   . ASN A 1 224 ? 110.432 126.905 124.817 1.00 29.70  ? 189 ASN A N   1 
ATOM   1443  C CA  . ASN A 1 224 ? 110.475 126.425 126.191 1.00 31.00  ? 189 ASN A CA  1 
ATOM   1444  C C   . ASN A 1 224 ? 109.768 127.358 127.162 1.00 30.34  ? 189 ASN A C   1 
ATOM   1445  O O   . ASN A 1 224 ? 109.154 126.884 128.125 1.00 30.06  ? 189 ASN A O   1 
ATOM   1446  C CB  . ASN A 1 224 ? 111.926 126.236 126.638 1.00 36.11  ? 189 ASN A CB  1 
ATOM   1447  C CG  . ASN A 1 224 ? 112.641 125.158 125.852 1.00 49.64  ? 189 ASN A CG  1 
ATOM   1448  O OD1 . ASN A 1 224 ? 112.194 124.759 124.777 1.00 52.91  ? 189 ASN A OD1 1 
ATOM   1449  N ND2 . ASN A 1 224 ? 113.758 124.678 126.386 1.00 54.73  ? 189 ASN A ND2 1 
ATOM   1450  N N   . GLN A 1 225 ? 109.831 128.668 126.933 1.00 29.97  ? 190 GLN A N   1 
ATOM   1451  C CA  . GLN A 1 225 ? 109.331 129.654 127.882 1.00 26.73  ? 190 GLN A CA  1 
ATOM   1452  C C   . GLN A 1 225 ? 108.133 130.426 127.352 1.00 27.45  ? 190 GLN A C   1 
ATOM   1453  O O   . GLN A 1 225 ? 107.675 131.364 128.011 1.00 29.92  ? 190 GLN A O   1 
ATOM   1454  C CB  . GLN A 1 225 ? 110.442 130.632 128.260 1.00 26.23  ? 190 GLN A CB  1 
ATOM   1455  C CG  . GLN A 1 225 ? 111.440 130.880 127.145 1.00 30.44  ? 190 GLN A CG  1 
ATOM   1456  C CD  . GLN A 1 225 ? 112.457 131.941 127.501 1.00 41.13  ? 190 GLN A CD  1 
ATOM   1457  O OE1 . GLN A 1 225 ? 112.517 132.400 128.642 1.00 45.09  ? 190 GLN A OE1 1 
ATOM   1458  N NE2 . GLN A 1 225 ? 113.268 132.335 126.527 1.00 42.99  ? 190 GLN A NE2 1 
ATOM   1459  N N   . TYR A 1 226 ? 107.610 130.055 126.189 1.00 27.17  ? 191 TYR A N   1 
ATOM   1460  C CA  . TYR A 1 226 ? 106.512 130.788 125.584 1.00 23.92  ? 191 TYR A CA  1 
ATOM   1461  C C   . TYR A 1 226 ? 105.487 129.805 125.045 1.00 23.30  ? 191 TYR A C   1 
ATOM   1462  O O   . TYR A 1 226 ? 105.784 128.634 124.797 1.00 27.28  ? 191 TYR A O   1 
ATOM   1463  C CB  . TYR A 1 226 ? 106.994 131.698 124.445 1.00 21.57  ? 191 TYR A CB  1 
ATOM   1464  C CG  . TYR A 1 226 ? 107.872 132.848 124.882 1.00 22.72  ? 191 TYR A CG  1 
ATOM   1465  C CD1 . TYR A 1 226 ? 107.321 134.063 125.263 1.00 24.82  ? 191 TYR A CD1 1 
ATOM   1466  C CD2 . TYR A 1 226 ? 109.252 132.722 124.901 1.00 24.25  ? 191 TYR A CD2 1 
ATOM   1467  C CE1 . TYR A 1 226 ? 108.120 135.115 125.659 1.00 25.07  ? 191 TYR A CE1 1 
ATOM   1468  C CE2 . TYR A 1 226 ? 110.059 133.768 125.293 1.00 26.13  ? 191 TYR A CE2 1 
ATOM   1469  C CZ  . TYR A 1 226 ? 109.488 134.962 125.672 1.00 27.86  ? 191 TYR A CZ  1 
ATOM   1470  O OH  . TYR A 1 226 ? 110.292 136.006 126.064 1.00 36.02  ? 191 TYR A OH  1 
ATOM   1471  N N   . ASP A 1 227 ? 104.267 130.298 124.873 1.00 25.33  ? 192 ASP A N   1 
ATOM   1472  C CA  . ASP A 1 227 ? 103.222 129.592 124.152 1.00 32.14  ? 192 ASP A CA  1 
ATOM   1473  C C   . ASP A 1 227 ? 102.888 130.406 122.916 1.00 31.10  ? 192 ASP A C   1 
ATOM   1474  O O   . ASP A 1 227 ? 102.666 131.617 123.013 1.00 31.77  ? 192 ASP A O   1 
ATOM   1475  C CB  . ASP A 1 227 ? 101.971 129.398 125.014 1.00 42.05  ? 192 ASP A CB  1 
ATOM   1476  C CG  . ASP A 1 227 ? 102.246 128.606 126.274 1.00 47.29  ? 192 ASP A CG  1 
ATOM   1477  O OD1 . ASP A 1 227 ? 102.845 127.516 126.169 1.00 45.97  ? 192 ASP A OD1 1 
ATOM   1478  O OD2 . ASP A 1 227 ? 101.860 129.069 127.368 1.00 43.94  ? 192 ASP A OD2 1 
ATOM   1479  N N   . LEU A 1 228 ? 102.849 129.754 121.759 1.00 29.48  ? 193 LEU A N   1 
ATOM   1480  C CA  . LEU A 1 228 ? 102.505 130.459 120.530 1.00 26.59  ? 193 LEU A CA  1 
ATOM   1481  C C   . LEU A 1 228 ? 100.986 130.487 120.437 1.00 31.76  ? 193 LEU A C   1 
ATOM   1482  O O   . LEU A 1 228 ? 100.360 129.542 119.954 1.00 37.50  ? 193 LEU A O   1 
ATOM   1483  C CB  . LEU A 1 228 ? 103.138 129.778 119.323 1.00 30.39  ? 193 LEU A CB  1 
ATOM   1484  C CG  . LEU A 1 228 ? 102.877 130.396 117.950 1.00 35.75  ? 193 LEU A CG  1 
ATOM   1485  C CD1 . LEU A 1 228 ? 103.378 131.826 117.901 1.00 30.21  ? 193 LEU A CD1 1 
ATOM   1486  C CD2 . LEU A 1 228 ? 103.539 129.563 116.865 1.00 35.29  ? 193 LEU A CD2 1 
ATOM   1487  N N   . LEU A 1 229 ? 100.393 131.587 120.905 1.00 31.77  ? 194 LEU A N   1 
ATOM   1488  C CA  . LEU A 1 229 ? 98.940  131.711 120.897 1.00 35.68  ? 194 LEU A CA  1 
ATOM   1489  C C   . LEU A 1 229 ? 98.399  131.752 119.477 1.00 43.92  ? 194 LEU A C   1 
ATOM   1490  O O   . LEU A 1 229 ? 97.373  131.132 119.174 1.00 56.42  ? 194 LEU A O   1 
ATOM   1491  C CB  . LEU A 1 229 ? 98.518  132.962 121.665 1.00 28.21  ? 194 LEU A CB  1 
ATOM   1492  C CG  . LEU A 1 229 ? 99.141  133.163 123.046 1.00 31.31  ? 194 LEU A CG  1 
ATOM   1493  C CD1 . LEU A 1 229 ? 98.586  134.419 123.693 1.00 35.70  ? 194 LEU A CD1 1 
ATOM   1494  C CD2 . LEU A 1 229 ? 98.909  131.948 123.932 1.00 29.03  ? 194 LEU A CD2 1 
ATOM   1495  N N   . GLY A 1 230 ? 99.079  132.475 118.598 1.00 36.30  ? 195 GLY A N   1 
ATOM   1496  C CA  . GLY A 1 230 ? 98.627  132.629 117.235 1.00 33.99  ? 195 GLY A CA  1 
ATOM   1497  C C   . GLY A 1 230 ? 99.433  133.716 116.558 1.00 30.52  ? 195 GLY A C   1 
ATOM   1498  O O   . GLY A 1 230 ? 100.476 134.142 117.058 1.00 29.75  ? 195 GLY A O   1 
ATOM   1499  N N   . GLN A 1 231 ? 98.931  134.158 115.411 1.00 31.09  ? 196 GLN A N   1 
ATOM   1500  C CA  . GLN A 1 231 ? 99.591  135.239 114.703 1.00 26.43  ? 196 GLN A CA  1 
ATOM   1501  C C   . GLN A 1 231 ? 98.550  136.087 113.995 1.00 28.42  ? 196 GLN A C   1 
ATOM   1502  O O   . GLN A 1 231 ? 97.429  135.644 113.730 1.00 32.62  ? 196 GLN A O   1 
ATOM   1503  C CB  . GLN A 1 231 ? 100.613 134.707 113.691 1.00 28.08  ? 196 GLN A CB  1 
ATOM   1504  C CG  . GLN A 1 231 ? 99.992  133.985 112.508 1.00 28.34  ? 196 GLN A CG  1 
ATOM   1505  C CD  . GLN A 1 231 ? 99.932  132.487 112.701 1.00 32.43  ? 196 GLN A CD  1 
ATOM   1506  O OE1 . GLN A 1 231 ? 100.554 131.941 113.612 1.00 36.20  ? 196 GLN A OE1 1 
ATOM   1507  N NE2 . GLN A 1 231 ? 99.182  131.810 111.841 1.00 33.22  ? 196 GLN A NE2 1 
ATOM   1508  N N   . THR A 1 232 ? 98.942  137.319 113.689 1.00 29.02  ? 197 THR A N   1 
ATOM   1509  C CA  . THR A 1 232 ? 98.159  138.212 112.853 1.00 33.21  ? 197 THR A CA  1 
ATOM   1510  C C   . THR A 1 232 ? 99.023  138.631 111.677 1.00 29.05  ? 197 THR A C   1 
ATOM   1511  O O   . THR A 1 232 ? 100.213 138.915 111.838 1.00 28.41  ? 197 THR A O   1 
ATOM   1512  C CB  . THR A 1 232 ? 97.681  139.442 113.628 1.00 31.32  ? 197 THR A CB  1 
ATOM   1513  O OG1 . THR A 1 232 ? 98.811  140.141 114.165 1.00 34.42  ? 197 THR A OG1 1 
ATOM   1514  C CG2 . THR A 1 232 ? 96.752  139.032 114.761 1.00 29.67  ? 197 THR A CG2 1 
ATOM   1515  N N   . VAL A 1 233 ? 98.418  138.665 110.497 1.00 31.47  ? 198 VAL A N   1 
ATOM   1516  C CA  . VAL A 1 233 ? 99.126  138.927 109.254 1.00 30.60  ? 198 VAL A CA  1 
ATOM   1517  C C   . VAL A 1 233 ? 98.588  140.209 108.637 1.00 36.62  ? 198 VAL A C   1 
ATOM   1518  O O   . VAL A 1 233 ? 97.377  140.340 108.421 1.00 45.00  ? 198 VAL A O   1 
ATOM   1519  C CB  . VAL A 1 233 ? 98.979  137.737 108.292 1.00 32.20  ? 198 VAL A CB  1 
ATOM   1520  C CG1 . VAL A 1 233 ? 99.787  137.959 107.064 1.00 30.52  ? 198 VAL A CG1 1 
ATOM   1521  C CG2 . VAL A 1 233 ? 99.415  136.455 108.985 1.00 32.53  ? 198 VAL A CG2 1 
ATOM   1522  N N   . ASP A 1 234 ? 99.487  141.144 108.340 1.00 31.47  ? 199 ASP A N   1 
ATOM   1523  C CA  . ASP A 1 234 ? 99.102  142.464 107.868 1.00 31.54  ? 199 ASP A CA  1 
ATOM   1524  C C   . ASP A 1 234 ? 100.104 142.926 106.818 1.00 31.13  ? 199 ASP A C   1 
ATOM   1525  O O   . ASP A 1 234 ? 101.115 142.269 106.561 1.00 35.54  ? 199 ASP A O   1 
ATOM   1526  C CB  . ASP A 1 234 ? 99.019  143.467 109.028 1.00 36.33  ? 199 ASP A CB  1 
ATOM   1527  C CG  . ASP A 1 234 ? 98.183  144.686 108.691 1.00 48.98  ? 199 ASP A CG  1 
ATOM   1528  O OD1 . ASP A 1 234 ? 97.483  144.659 107.657 1.00 49.00  ? 199 ASP A OD1 1 
ATOM   1529  O OD2 . ASP A 1 234 ? 98.224  145.670 109.457 1.00 56.25  ? 199 ASP A OD2 1 
ATOM   1530  N N   . SER A 1 235 ? 99.811  144.071 106.207 1.00 33.55  ? 200 SER A N   1 
ATOM   1531  C CA  . SER A 1 235 ? 100.725 144.705 105.270 1.00 35.15  ? 200 SER A CA  1 
ATOM   1532  C C   . SER A 1 235 ? 100.472 146.205 105.283 1.00 36.65  ? 200 SER A C   1 
ATOM   1533  O O   . SER A 1 235 ? 99.384  146.665 105.637 1.00 46.54  ? 200 SER A O   1 
ATOM   1534  C CB  . SER A 1 235 ? 100.566 144.141 103.854 1.00 33.44  ? 200 SER A CB  1 
ATOM   1535  O OG  . SER A 1 235 ? 99.276  144.415 103.339 1.00 38.04  ? 200 SER A OG  1 
ATOM   1536  N N   . GLY A 1 236 ? 101.481 146.963 104.886 1.00 29.12  ? 201 GLY A N   1 
ATOM   1537  C CA  . GLY A 1 236 ? 101.365 148.402 104.887 1.00 27.81  ? 201 GLY A CA  1 
ATOM   1538  C C   . GLY A 1 236 ? 102.417 149.067 104.034 1.00 32.48  ? 201 GLY A C   1 
ATOM   1539  O O   . GLY A 1 236 ? 102.953 148.471 103.099 1.00 36.89  ? 201 GLY A O   1 
ATOM   1540  N N   . ILE A 1 237 ? 102.708 150.323 104.368 1.00 35.12  ? 202 ILE A N   1 
ATOM   1541  C CA  . ILE A 1 237 ? 103.703 151.125 103.667 1.00 36.77  ? 202 ILE A CA  1 
ATOM   1542  C C   . ILE A 1 237 ? 104.641 151.758 104.684 1.00 38.57  ? 202 ILE A C   1 
ATOM   1543  O O   . ILE A 1 237 ? 104.208 152.185 105.760 1.00 39.81  ? 202 ILE A O   1 
ATOM   1544  C CB  . ILE A 1 237 ? 103.036 152.214 102.798 1.00 34.30  ? 202 ILE A CB  1 
ATOM   1545  C CG1 . ILE A 1 237 ? 102.123 151.584 101.746 1.00 31.60  ? 202 ILE A CG1 1 
ATOM   1546  C CG2 . ILE A 1 237 ? 104.080 153.093 102.130 1.00 44.04  ? 202 ILE A CG2 1 
ATOM   1547  C CD1 . ILE A 1 237 ? 102.852 150.720 100.750 1.00 32.63  ? 202 ILE A CD1 1 
ATOM   1548  N N   . VAL A 1 238 ? 105.928 151.809 104.347 1.00 41.55  ? 203 VAL A N   1 
ATOM   1549  C CA  . VAL A 1 238 ? 106.943 152.454 105.171 1.00 47.51  ? 203 VAL A CA  1 
ATOM   1550  C C   . VAL A 1 238 ? 107.690 153.451 104.297 1.00 55.74  ? 203 VAL A C   1 
ATOM   1551  O O   . VAL A 1 238 ? 108.061 153.138 103.160 1.00 51.33  ? 203 VAL A O   1 
ATOM   1552  C CB  . VAL A 1 238 ? 107.909 151.430 105.802 1.00 45.23  ? 203 VAL A CB  1 
ATOM   1553  C CG1 . VAL A 1 238 ? 109.175 152.112 106.290 1.00 50.30  ? 203 VAL A CG1 1 
ATOM   1554  C CG2 . VAL A 1 238 ? 107.228 150.710 106.954 1.00 48.10  ? 203 VAL A CG2 1 
ATOM   1555  N N   . GLN A 1 239 ? 107.912 154.650 104.828 1.00 65.31  ? 204 GLN A N   1 
ATOM   1556  C CA  . GLN A 1 239 ? 108.660 155.693 104.138 1.00 62.44  ? 204 GLN A CA  1 
ATOM   1557  C C   . GLN A 1 239 ? 110.052 155.819 104.742 1.00 63.18  ? 204 GLN A C   1 
ATOM   1558  O O   . GLN A 1 239 ? 110.205 155.833 105.968 1.00 71.17  ? 204 GLN A O   1 
ATOM   1559  C CB  . GLN A 1 239 ? 107.927 157.034 104.205 1.00 61.44  ? 204 GLN A CB  1 
ATOM   1560  C CG  . GLN A 1 239 ? 106.479 156.964 103.753 1.00 68.74  ? 204 GLN A CG  1 
ATOM   1561  C CD  . GLN A 1 239 ? 105.822 158.328 103.692 1.00 80.89  ? 204 GLN A CD  1 
ATOM   1562  O OE1 . GLN A 1 239 ? 106.479 159.354 103.865 1.00 87.07  ? 204 GLN A OE1 1 
ATOM   1563  N NE2 . GLN A 1 239 ? 104.519 158.346 103.437 1.00 78.36  ? 204 GLN A NE2 1 
ATOM   1564  N N   . SER A 1 240 ? 111.060 155.908 103.877 1.00 56.99  ? 205 SER A N   1 
ATOM   1565  C CA  . SER A 1 240 ? 112.438 156.095 104.311 1.00 58.27  ? 205 SER A CA  1 
ATOM   1566  C C   . SER A 1 240 ? 113.112 157.175 103.475 1.00 60.68  ? 205 SER A C   1 
ATOM   1567  O O   . SER A 1 240 ? 112.452 157.853 102.682 1.00 65.38  ? 205 SER A O   1 
ATOM   1568  C CB  . SER A 1 240 ? 113.213 154.779 104.224 1.00 53.51  ? 205 SER A CB  1 
ATOM   1569  O OG  . SER A 1 240 ? 113.252 154.297 102.893 1.00 57.67  ? 205 SER A OG  1 
ATOM   1570  N N   . SER A 1 241 ? 114.424 157.351 103.651 1.00 60.92  ? 206 SER A N   1 
ATOM   1571  C CA  . SER A 1 241 ? 115.139 158.386 102.914 1.00 63.65  ? 206 SER A CA  1 
ATOM   1572  C C   . SER A 1 241 ? 115.196 158.117 101.416 1.00 65.17  ? 206 SER A C   1 
ATOM   1573  O O   . SER A 1 241 ? 115.487 159.040 100.648 1.00 65.53  ? 206 SER A O   1 
ATOM   1574  C CB  . SER A 1 241 ? 116.557 158.536 103.468 1.00 67.12  ? 206 SER A CB  1 
ATOM   1575  O OG  . SER A 1 241 ? 117.290 157.331 103.332 1.00 68.21  ? 206 SER A OG  1 
ATOM   1576  N N   . THR A 1 242 ? 114.932 156.888 100.979 1.00 64.20  ? 207 THR A N   1 
ATOM   1577  C CA  . THR A 1 242 ? 115.037 156.536 99.570  1.00 61.85  ? 207 THR A CA  1 
ATOM   1578  C C   . THR A 1 242 ? 113.683 156.395 98.888  1.00 58.84  ? 207 THR A C   1 
ATOM   1579  O O   . THR A 1 242 ? 113.637 156.148 97.679  1.00 61.52  ? 207 THR A O   1 
ATOM   1580  C CB  . THR A 1 242 ? 115.832 155.238 99.403  1.00 57.80  ? 207 THR A CB  1 
ATOM   1581  O OG1 . THR A 1 242 ? 115.239 154.203 100.197 1.00 54.78  ? 207 THR A OG1 1 
ATOM   1582  C CG2 . THR A 1 242 ? 117.271 155.438 99.828  1.00 57.47  ? 207 THR A CG2 1 
ATOM   1583  N N   . GLY A 1 243 ? 112.587 156.549 99.624  1.00 54.65  ? 208 GLY A N   1 
ATOM   1584  C CA  . GLY A 1 243 ? 111.252 156.502 99.075  1.00 53.70  ? 208 GLY A CA  1 
ATOM   1585  C C   . GLY A 1 243 ? 110.343 155.650 99.928  1.00 55.99  ? 208 GLY A C   1 
ATOM   1586  O O   . GLY A 1 243 ? 110.652 155.317 101.077 1.00 56.67  ? 208 GLY A O   1 
ATOM   1587  N N   . GLU A 1 244 ? 109.199 155.288 99.356  1.00 54.34  ? 209 GLU A N   1 
ATOM   1588  C CA  . GLU A 1 244 ? 108.196 154.481 100.033 1.00 51.59  ? 209 GLU A CA  1 
ATOM   1589  C C   . GLU A 1 244 ? 108.267 153.047 99.530  1.00 50.72  ? 209 GLU A C   1 
ATOM   1590  O O   . GLU A 1 244 ? 108.391 152.805 98.327  1.00 53.52  ? 209 GLU A O   1 
ATOM   1591  C CB  . GLU A 1 244 ? 106.792 155.048 99.820  1.00 54.80  ? 209 GLU A CB  1 
ATOM   1592  C CG  . GLU A 1 244 ? 106.678 156.531 100.124 1.00 60.57  ? 209 GLU A CG  1 
ATOM   1593  C CD  . GLU A 1 244 ? 105.241 156.991 100.250 1.00 64.54  ? 209 GLU A CD  1 
ATOM   1594  O OE1 . GLU A 1 244 ? 104.340 156.128 100.268 1.00 60.72  ? 209 GLU A OE1 1 
ATOM   1595  O OE2 . GLU A 1 244 ? 105.013 158.216 100.334 1.00 68.44  ? 209 GLU A OE2 1 
ATOM   1596  N N   . TYR A 1 245 ? 108.182 152.097 100.457 1.00 47.93  ? 210 TYR A N   1 
ATOM   1597  C CA  . TYR A 1 245 ? 108.312 150.685 100.138 1.00 45.60  ? 210 TYR A CA  1 
ATOM   1598  C C   . TYR A 1 245 ? 107.169 149.906 100.770 1.00 41.66  ? 210 TYR A C   1 
ATOM   1599  O O   . TYR A 1 245 ? 106.675 150.256 101.845 1.00 40.40  ? 210 TYR A O   1 
ATOM   1600  C CB  . TYR A 1 245 ? 109.654 150.117 100.630 1.00 44.18  ? 210 TYR A CB  1 
ATOM   1601  C CG  . TYR A 1 245 ? 110.869 150.799 100.044 1.00 41.92  ? 210 TYR A CG  1 
ATOM   1602  C CD1 . TYR A 1 245 ? 111.363 151.976 100.586 1.00 48.49  ? 210 TYR A CD1 1 
ATOM   1603  C CD2 . TYR A 1 245 ? 111.525 150.259 98.951  1.00 40.67  ? 210 TYR A CD2 1 
ATOM   1604  C CE1 . TYR A 1 245 ? 112.472 152.598 100.048 1.00 49.47  ? 210 TYR A CE1 1 
ATOM   1605  C CE2 . TYR A 1 245 ? 112.633 150.871 98.407  1.00 45.64  ? 210 TYR A CE2 1 
ATOM   1606  C CZ  . TYR A 1 245 ? 113.103 152.040 98.958  1.00 48.35  ? 210 TYR A CZ  1 
ATOM   1607  O OH  . TYR A 1 245 ? 114.210 152.647 98.416  1.00 50.45  ? 210 TYR A OH  1 
ATOM   1608  N N   . VAL A 1 246 ? 106.760 148.840 100.091 1.00 40.88  ? 211 VAL A N   1 
ATOM   1609  C CA  . VAL A 1 246 ? 105.765 147.925 100.637 1.00 36.76  ? 211 VAL A CA  1 
ATOM   1610  C C   . VAL A 1 246 ? 106.445 147.006 101.640 1.00 27.87  ? 211 VAL A C   1 
ATOM   1611  O O   . VAL A 1 246 ? 107.510 146.443 101.366 1.00 26.66  ? 211 VAL A O   1 
ATOM   1612  C CB  . VAL A 1 246 ? 105.087 147.124 99.515  1.00 36.13  ? 211 VAL A CB  1 
ATOM   1613  C CG1 . VAL A 1 246 ? 104.223 146.017 100.098 1.00 32.51  ? 211 VAL A CG1 1 
ATOM   1614  C CG2 . VAL A 1 246 ? 104.258 148.044 98.635  1.00 37.20  ? 211 VAL A CG2 1 
ATOM   1615  N N   . VAL A 1 247 ? 105.828 146.853 102.807 1.00 23.14  ? 212 VAL A N   1 
ATOM   1616  C CA  . VAL A 1 247 ? 106.346 146.014 103.879 1.00 22.28  ? 212 VAL A CA  1 
ATOM   1617  C C   . VAL A 1 247 ? 105.296 144.975 104.230 1.00 22.38  ? 212 VAL A C   1 
ATOM   1618  O O   . VAL A 1 247 ? 104.148 145.321 104.533 1.00 25.43  ? 212 VAL A O   1 
ATOM   1619  C CB  . VAL A 1 247 ? 106.728 146.840 105.116 1.00 23.71  ? 212 VAL A CB  1 
ATOM   1620  C CG1 . VAL A 1 247 ? 107.343 145.950 106.178 1.00 19.73  ? 212 VAL A CG1 1 
ATOM   1621  C CG2 . VAL A 1 247 ? 107.698 147.935 104.724 1.00 30.75  ? 212 VAL A CG2 1 
ATOM   1622  N N   . MET A 1 248 ? 105.685 143.707 104.178 1.00 24.27  ? 213 MET A N   1 
ATOM   1623  C CA  . MET A 1 248 ? 104.837 142.609 104.616 1.00 23.08  ? 213 MET A CA  1 
ATOM   1624  C C   . MET A 1 248 ? 105.251 142.220 106.023 1.00 17.98  ? 213 MET A C   1 
ATOM   1625  O O   . MET A 1 248 ? 106.434 141.984 106.284 1.00 20.73  ? 213 MET A O   1 
ATOM   1626  C CB  . MET A 1 248 ? 104.956 141.403 103.689 1.00 23.65  ? 213 MET A CB  1 
ATOM   1627  C CG  . MET A 1 248 ? 104.846 141.744 102.234 1.00 24.05  ? 213 MET A CG  1 
ATOM   1628  S SD  . MET A 1 248 ? 103.209 142.382 101.869 1.00 40.17  ? 213 MET A SD  1 
ATOM   1629  C CE  . MET A 1 248 ? 102.290 140.853 101.866 1.00 28.88  ? 213 MET A CE  1 
ATOM   1630  N N   . THR A 1 249 ? 104.281 142.148 106.921 1.00 15.76  ? 214 THR A N   1 
ATOM   1631  C CA  . THR A 1 249 ? 104.560 141.984 108.334 1.00 18.32  ? 214 THR A CA  1 
ATOM   1632  C C   . THR A 1 249 ? 103.811 140.774 108.859 1.00 20.67  ? 214 THR A C   1 
ATOM   1633  O O   . THR A 1 249 ? 102.744 140.410 108.358 1.00 27.27  ? 214 THR A O   1 
ATOM   1634  C CB  . THR A 1 249 ? 104.158 143.223 109.150 1.00 26.88  ? 214 THR A CB  1 
ATOM   1635  O OG1 . THR A 1 249 ? 102.736 143.240 109.327 1.00 38.22  ? 214 THR A OG1 1 
ATOM   1636  C CG2 . THR A 1 249 ? 104.592 144.500 108.447 1.00 24.86  ? 214 THR A CG2 1 
ATOM   1637  N N   . THR A 1 250 ? 104.388 140.155 109.879 1.00 21.04  ? 215 THR A N   1 
ATOM   1638  C CA  . THR A 1 250 ? 103.754 139.056 110.584 1.00 25.62  ? 215 THR A CA  1 
ATOM   1639  C C   . THR A 1 250 ? 104.151 139.194 112.039 1.00 28.26  ? 215 THR A C   1 
ATOM   1640  O O   . THR A 1 250 ? 105.337 139.332 112.351 1.00 31.97  ? 215 THR A O   1 
ATOM   1641  C CB  . THR A 1 250 ? 104.194 137.695 110.033 1.00 24.18  ? 215 THR A CB  1 
ATOM   1642  O OG1 . THR A 1 250 ? 103.992 137.660 108.616 1.00 25.40  ? 215 THR A OG1 1 
ATOM   1643  C CG2 . THR A 1 250 ? 103.397 136.576 110.681 1.00 24.85  ? 215 THR A CG2 1 
ATOM   1644  N N   . HIS A 1 251 ? 103.167 139.143 112.923 1.00 25.81  ? 216 HIS A N   1 
ATOM   1645  C CA  . HIS A 1 251 ? 103.403 139.224 114.353 1.00 23.50  ? 216 HIS A CA  1 
ATOM   1646  C C   . HIS A 1 251 ? 103.041 137.894 114.985 1.00 25.70  ? 216 HIS A C   1 
ATOM   1647  O O   . HIS A 1 251 ? 101.930 137.393 114.793 1.00 30.13  ? 216 HIS A O   1 
ATOM   1648  C CB  . HIS A 1 251 ? 102.588 140.356 114.978 1.00 24.03  ? 216 HIS A CB  1 
ATOM   1649  C CG  . HIS A 1 251 ? 103.086 141.723 114.626 1.00 33.25  ? 216 HIS A CG  1 
ATOM   1650  N ND1 . HIS A 1 251 ? 102.714 142.376 113.471 1.00 37.24  ? 216 HIS A ND1 1 
ATOM   1651  C CD2 . HIS A 1 251 ? 103.933 142.558 115.273 1.00 37.50  ? 216 HIS A CD2 1 
ATOM   1652  C CE1 . HIS A 1 251 ? 103.308 143.555 113.424 1.00 38.05  ? 216 HIS A CE1 1 
ATOM   1653  N NE2 . HIS A 1 251 ? 104.054 143.690 114.505 1.00 41.02  ? 216 HIS A NE2 1 
ATOM   1654  N N   . PHE A 1 252 ? 103.971 137.336 115.743 1.00 24.13  ? 217 PHE A N   1 
ATOM   1655  C CA  . PHE A 1 252 ? 103.730 136.121 116.502 1.00 23.57  ? 217 PHE A CA  1 
ATOM   1656  C C   . PHE A 1 252 ? 103.455 136.522 117.940 1.00 24.69  ? 217 PHE A C   1 
ATOM   1657  O O   . PHE A 1 252 ? 104.312 137.122 118.597 1.00 27.10  ? 217 PHE A O   1 
ATOM   1658  C CB  . PHE A 1 252 ? 104.922 135.167 116.418 1.00 23.27  ? 217 PHE A CB  1 
ATOM   1659  C CG  . PHE A 1 252 ? 105.255 134.736 115.020 1.00 22.21  ? 217 PHE A CG  1 
ATOM   1660  C CD1 . PHE A 1 252 ? 104.642 133.630 114.461 1.00 24.11  ? 217 PHE A CD1 1 
ATOM   1661  C CD2 . PHE A 1 252 ? 106.177 135.438 114.264 1.00 23.21  ? 217 PHE A CD2 1 
ATOM   1662  C CE1 . PHE A 1 252 ? 104.944 133.231 113.175 1.00 23.95  ? 217 PHE A CE1 1 
ATOM   1663  C CE2 . PHE A 1 252 ? 106.482 135.045 112.977 1.00 23.10  ? 217 PHE A CE2 1 
ATOM   1664  C CZ  . PHE A 1 252 ? 105.864 133.940 112.432 1.00 22.66  ? 217 PHE A CZ  1 
ATOM   1665  N N   . HIS A 1 253 ? 102.264 136.197 118.423 1.00 24.70  ? 218 HIS A N   1 
ATOM   1666  C CA  . HIS A 1 253 ? 101.853 136.585 119.762 1.00 23.26  ? 218 HIS A CA  1 
ATOM   1667  C C   . HIS A 1 253 ? 102.301 135.489 120.714 1.00 26.37  ? 218 HIS A C   1 
ATOM   1668  O O   . HIS A 1 253 ? 101.907 134.327 120.567 1.00 34.59  ? 218 HIS A O   1 
ATOM   1669  C CB  . HIS A 1 253 ? 100.344 136.803 119.836 1.00 26.66  ? 218 HIS A CB  1 
ATOM   1670  C CG  . HIS A 1 253 ? 99.838  137.822 118.866 1.00 29.87  ? 218 HIS A CG  1 
ATOM   1671  N ND1 . HIS A 1 253 ? 100.057 139.173 119.027 1.00 31.85  ? 218 HIS A ND1 1 
ATOM   1672  C CD2 . HIS A 1 253 ? 99.134  137.689 117.718 1.00 34.32  ? 218 HIS A CD2 1 
ATOM   1673  C CE1 . HIS A 1 253 ? 99.504  139.829 118.023 1.00 36.34  ? 218 HIS A CE1 1 
ATOM   1674  N NE2 . HIS A 1 253 ? 98.938  138.952 117.214 1.00 38.32  ? 218 HIS A NE2 1 
ATOM   1675  N N   . LEU A 1 254 ? 103.118 135.865 121.685 1.00 22.77  ? 219 LEU A N   1 
ATOM   1676  C CA  . LEU A 1 254 ? 103.712 134.929 122.619 1.00 22.46  ? 219 LEU A CA  1 
ATOM   1677  C C   . LEU A 1 254 ? 103.297 135.301 124.029 1.00 20.93  ? 219 LEU A C   1 
ATOM   1678  O O   . LEU A 1 254 ? 103.180 136.483 124.363 1.00 24.97  ? 219 LEU A O   1 
ATOM   1679  C CB  . LEU A 1 254 ? 105.237 134.944 122.513 1.00 20.19  ? 219 LEU A CB  1 
ATOM   1680  C CG  . LEU A 1 254 ? 105.845 134.721 121.130 1.00 19.78  ? 219 LEU A CG  1 
ATOM   1681  C CD1 . LEU A 1 254 ? 107.358 134.696 121.224 1.00 22.67  ? 219 LEU A CD1 1 
ATOM   1682  C CD2 . LEU A 1 254 ? 105.329 133.435 120.519 1.00 24.42  ? 219 LEU A CD2 1 
ATOM   1683  N N   . LYS A 1 255 ? 103.077 134.283 124.849 1.00 19.24  ? 220 LYS A N   1 
ATOM   1684  C CA  . LYS A 1 255 ? 102.753 134.465 126.251 1.00 21.90  ? 220 LYS A CA  1 
ATOM   1685  C C   . LYS A 1 255 ? 103.707 133.590 127.040 1.00 24.87  ? 220 LYS A C   1 
ATOM   1686  O O   . LYS A 1 255 ? 103.896 132.416 126.710 1.00 29.95  ? 220 LYS A O   1 
ATOM   1687  C CB  . LYS A 1 255 ? 101.296 134.092 126.542 1.00 30.18  ? 220 LYS A CB  1 
ATOM   1688  C CG  . LYS A 1 255 ? 100.835 134.431 127.947 1.00 30.97  ? 220 LYS A CG  1 
ATOM   1689  C CD  . LYS A 1 255 ? 99.354  134.144 128.118 1.00 33.14  ? 220 LYS A CD  1 
ATOM   1690  C CE  . LYS A 1 255 ? 98.848  134.623 129.465 1.00 40.14  ? 220 LYS A CE  1 
ATOM   1691  N NZ  . LYS A 1 255 ? 97.376  134.436 129.593 1.00 53.78  ? 220 LYS A NZ  1 
ATOM   1692  N N   . ARG A 1 256 ? 104.304 134.161 128.077 1.00 20.33  ? 221 ARG A N   1 
ATOM   1693  C CA  . ARG A 1 256 ? 105.324 133.457 128.832 1.00 19.66  ? 221 ARG A CA  1 
ATOM   1694  C C   . ARG A 1 256 ? 104.678 132.479 129.799 1.00 22.35  ? 221 ARG A C   1 
ATOM   1695  O O   . ARG A 1 256 ? 103.677 132.793 130.448 1.00 27.67  ? 221 ARG A O   1 
ATOM   1696  C CB  . ARG A 1 256 ? 106.209 134.450 129.581 1.00 19.61  ? 221 ARG A CB  1 
ATOM   1697  C CG  . ARG A 1 256 ? 107.428 133.828 130.228 1.00 22.61  ? 221 ARG A CG  1 
ATOM   1698  C CD  . ARG A 1 256 ? 108.202 134.859 131.016 1.00 21.85  ? 221 ARG A CD  1 
ATOM   1699  N NE  . ARG A 1 256 ? 108.519 136.015 130.187 1.00 24.90  ? 221 ARG A NE  1 
ATOM   1700  C CZ  . ARG A 1 256 ? 109.599 136.119 129.424 1.00 28.53  ? 221 ARG A CZ  1 
ATOM   1701  N NH1 . ARG A 1 256 ? 110.499 135.152 129.366 1.00 29.01  ? 221 ARG A NH1 1 
ATOM   1702  N NH2 . ARG A 1 256 ? 109.781 137.222 128.705 1.00 28.11  ? 221 ARG A NH2 1 
ATOM   1703  N N   . LYS A 1 257 ? 105.254 131.284 129.887 1.00 21.22  ? 222 LYS A N   1 
ATOM   1704  C CA  . LYS A 1 257 ? 104.796 130.325 130.877 1.00 24.50  ? 222 LYS A CA  1 
ATOM   1705  C C   . LYS A 1 257 ? 105.286 130.761 132.247 1.00 24.89  ? 222 LYS A C   1 
ATOM   1706  O O   . LYS A 1 257 ? 106.468 131.069 132.427 1.00 25.62  ? 222 LYS A O   1 
ATOM   1707  C CB  . LYS A 1 257 ? 105.323 128.928 130.559 1.00 28.48  ? 222 LYS A CB  1 
ATOM   1708  C CG  . LYS A 1 257 ? 105.052 128.438 129.150 1.00 30.97  ? 222 LYS A CG  1 
ATOM   1709  C CD  . LYS A 1 257 ? 105.876 127.195 128.858 1.00 31.42  ? 222 LYS A CD  1 
ATOM   1710  C CE  . LYS A 1 257 ? 105.617 126.662 127.463 1.00 32.95  ? 222 LYS A CE  1 
ATOM   1711  N NZ  . LYS A 1 257 ? 106.515 125.522 127.132 1.00 39.56  ? 222 LYS A NZ  1 
ATOM   1712  N N   . ILE A 1 258 ? 104.377 130.785 133.217 1.00 23.51  ? 223 ILE A N   1 
ATOM   1713  C CA  . ILE A 1 258 ? 104.714 131.300 134.534 1.00 22.29  ? 223 ILE A CA  1 
ATOM   1714  C C   . ILE A 1 258 ? 105.039 130.182 135.517 1.00 24.92  ? 223 ILE A C   1 
ATOM   1715  O O   . ILE A 1 258 ? 105.627 130.457 136.573 1.00 27.47  ? 223 ILE A O   1 
ATOM   1716  C CB  . ILE A 1 258 ? 103.570 132.186 135.075 1.00 24.18  ? 223 ILE A CB  1 
ATOM   1717  C CG1 . ILE A 1 258 ? 104.049 133.057 136.238 1.00 24.15  ? 223 ILE A CG1 1 
ATOM   1718  C CG2 . ILE A 1 258 ? 102.381 131.332 135.486 1.00 25.86  ? 223 ILE A CG2 1 
ATOM   1719  C CD1 . ILE A 1 258 ? 102.962 133.912 136.845 1.00 23.49  ? 223 ILE A CD1 1 
ATOM   1720  N N   . GLY A 1 259 ? 104.680 128.932 135.203 1.00 23.39  ? 224 GLY A N   1 
ATOM   1721  C CA  . GLY A 1 259 ? 104.828 127.872 136.183 1.00 21.61  ? 224 GLY A CA  1 
ATOM   1722  C C   . GLY A 1 259 ? 106.260 127.695 136.645 1.00 21.58  ? 224 GLY A C   1 
ATOM   1723  O O   . GLY A 1 259 ? 106.503 127.353 137.804 1.00 24.76  ? 224 GLY A O   1 
ATOM   1724  N N   . TYR A 1 260 ? 107.224 127.910 135.745 1.00 20.68  ? 225 TYR A N   1 
ATOM   1725  C CA  . TYR A 1 260 ? 108.626 127.795 136.133 1.00 21.34  ? 225 TYR A CA  1 
ATOM   1726  C C   . TYR A 1 260 ? 108.984 128.817 137.200 1.00 21.07  ? 225 TYR A C   1 
ATOM   1727  O O   . TYR A 1 260 ? 109.669 128.495 138.177 1.00 21.21  ? 225 TYR A O   1 
ATOM   1728  C CB  . TYR A 1 260 ? 109.538 127.957 134.921 1.00 20.50  ? 225 TYR A CB  1 
ATOM   1729  C CG  . TYR A 1 260 ? 110.997 127.781 135.267 1.00 21.33  ? 225 TYR A CG  1 
ATOM   1730  C CD1 . TYR A 1 260 ? 111.502 126.539 135.625 1.00 20.93  ? 225 TYR A CD1 1 
ATOM   1731  C CD2 . TYR A 1 260 ? 111.867 128.863 135.256 1.00 21.14  ? 225 TYR A CD2 1 
ATOM   1732  C CE1 . TYR A 1 260 ? 112.833 126.377 135.949 1.00 20.96  ? 225 TYR A CE1 1 
ATOM   1733  C CE2 . TYR A 1 260 ? 113.200 128.711 135.579 1.00 19.61  ? 225 TYR A CE2 1 
ATOM   1734  C CZ  . TYR A 1 260 ? 113.678 127.465 135.924 1.00 20.89  ? 225 TYR A CZ  1 
ATOM   1735  O OH  . TYR A 1 260 ? 115.006 127.308 136.247 1.00 20.93  ? 225 TYR A OH  1 
ATOM   1736  N N   . PHE A 1 261 ? 108.529 130.059 137.028 1.00 21.22  ? 226 PHE A N   1 
ATOM   1737  C CA  . PHE A 1 261 ? 108.930 131.135 137.922 1.00 19.82  ? 226 PHE A CA  1 
ATOM   1738  C C   . PHE A 1 261 ? 108.197 131.080 139.250 1.00 18.12  ? 226 PHE A C   1 
ATOM   1739  O O   . PHE A 1 261 ? 108.683 131.644 140.235 1.00 19.50  ? 226 PHE A O   1 
ATOM   1740  C CB  . PHE A 1 261 ? 108.689 132.494 137.261 1.00 19.22  ? 226 PHE A CB  1 
ATOM   1741  C CG  . PHE A 1 261 ? 109.389 132.663 135.941 1.00 19.55  ? 226 PHE A CG  1 
ATOM   1742  C CD1 . PHE A 1 261 ? 108.807 132.211 134.770 1.00 20.97  ? 226 PHE A CD1 1 
ATOM   1743  C CD2 . PHE A 1 261 ? 110.630 133.269 135.874 1.00 20.54  ? 226 PHE A CD2 1 
ATOM   1744  C CE1 . PHE A 1 261 ? 109.447 132.365 133.556 1.00 21.88  ? 226 PHE A CE1 1 
ATOM   1745  C CE2 . PHE A 1 261 ? 111.275 133.423 134.665 1.00 21.80  ? 226 PHE A CE2 1 
ATOM   1746  C CZ  . PHE A 1 261 ? 110.683 132.970 133.504 1.00 22.10  ? 226 PHE A CZ  1 
ATOM   1747  N N   . VAL A 1 262 ? 107.045 130.411 139.299 1.00 16.93  ? 227 VAL A N   1 
ATOM   1748  C CA  . VAL A 1 262 ? 106.335 130.256 140.562 1.00 16.34  ? 227 VAL A CA  1 
ATOM   1749  C C   . VAL A 1 262 ? 107.089 129.306 141.481 1.00 18.31  ? 227 VAL A C   1 
ATOM   1750  O O   . VAL A 1 262 ? 107.271 129.587 142.670 1.00 19.73  ? 227 VAL A O   1 
ATOM   1751  C CB  . VAL A 1 262 ? 104.894 129.781 140.307 1.00 14.59  ? 227 VAL A CB  1 
ATOM   1752  C CG1 . VAL A 1 262 ? 104.198 129.468 141.618 1.00 13.78  ? 227 VAL A CG1 1 
ATOM   1753  C CG2 . VAL A 1 262 ? 104.122 130.832 139.530 1.00 13.76  ? 227 VAL A CG2 1 
ATOM   1754  N N   . ILE A 1 263 ? 107.561 128.180 140.944 1.00 18.89  ? 228 ILE A N   1 
ATOM   1755  C CA  . ILE A 1 263 ? 108.265 127.202 141.766 1.00 20.96  ? 228 ILE A CA  1 
ATOM   1756  C C   . ILE A 1 263 ? 109.714 127.602 142.023 1.00 21.31  ? 228 ILE A C   1 
ATOM   1757  O O   . ILE A 1 263 ? 110.292 127.198 143.041 1.00 24.34  ? 228 ILE A O   1 
ATOM   1758  C CB  . ILE A 1 263 ? 108.162 125.821 141.093 1.00 23.22  ? 228 ILE A CB  1 
ATOM   1759  C CG1 . ILE A 1 263 ? 106.702 125.368 141.059 1.00 23.35  ? 228 ILE A CG1 1 
ATOM   1760  C CG2 . ILE A 1 263 ? 109.010 124.780 141.802 1.00 23.20  ? 228 ILE A CG2 1 
ATOM   1761  C CD1 . ILE A 1 263 ? 106.486 124.053 140.355 1.00 23.22  ? 228 ILE A CD1 1 
ATOM   1762  N N   . GLN A 1 264 ? 110.303 128.426 141.160 1.00 18.92  ? 229 GLN A N   1 
ATOM   1763  C CA  . GLN A 1 264 ? 111.703 128.803 141.305 1.00 19.74  ? 229 GLN A CA  1 
ATOM   1764  C C   . GLN A 1 264 ? 111.879 130.098 142.085 1.00 20.56  ? 229 GLN A C   1 
ATOM   1765  O O   . GLN A 1 264 ? 112.770 130.191 142.935 1.00 22.81  ? 229 GLN A O   1 
ATOM   1766  C CB  . GLN A 1 264 ? 112.367 128.927 139.933 1.00 22.36  ? 229 GLN A CB  1 
ATOM   1767  C CG  . GLN A 1 264 ? 112.554 127.601 139.221 1.00 25.67  ? 229 GLN A CG  1 
ATOM   1768  C CD  . GLN A 1 264 ? 113.505 126.675 139.954 1.00 27.31  ? 229 GLN A CD  1 
ATOM   1769  O OE1 . GLN A 1 264 ? 114.686 126.979 140.115 1.00 28.23  ? 229 GLN A OE1 1 
ATOM   1770  N NE2 . GLN A 1 264 ? 112.993 125.533 140.398 1.00 25.71  ? 229 GLN A NE2 1 
ATOM   1771  N N   . THR A 1 265 ? 111.045 131.100 141.815 1.00 19.20  ? 230 THR A N   1 
ATOM   1772  C CA  . THR A 1 265 ? 111.213 132.425 142.392 1.00 17.35  ? 230 THR A CA  1 
ATOM   1773  C C   . THR A 1 265 ? 110.094 132.784 143.362 1.00 15.46  ? 230 THR A C   1 
ATOM   1774  O O   . THR A 1 265 ? 110.367 133.103 144.521 1.00 16.76  ? 230 THR A O   1 
ATOM   1775  C CB  . THR A 1 265 ? 111.296 133.474 141.275 1.00 18.45  ? 230 THR A CB  1 
ATOM   1776  O OG1 . THR A 1 265 ? 112.332 133.114 140.353 1.00 17.94  ? 230 THR A OG1 1 
ATOM   1777  C CG2 . THR A 1 265 ? 111.593 134.844 141.855 1.00 20.93  ? 230 THR A CG2 1 
ATOM   1778  N N   . TYR A 1 266 ? 108.836 132.741 142.920 1.00 15.15  ? 231 TYR A N   1 
ATOM   1779  C CA  . TYR A 1 266 ? 107.756 133.288 143.735 1.00 13.74  ? 231 TYR A CA  1 
ATOM   1780  C C   . TYR A 1 266 ? 107.533 132.468 145.001 1.00 15.04  ? 231 TYR A C   1 
ATOM   1781  O O   . TYR A 1 266 ? 107.435 133.028 146.097 1.00 17.36  ? 231 TYR A O   1 
ATOM   1782  C CB  . TYR A 1 266 ? 106.477 133.387 142.909 1.00 13.31  ? 231 TYR A CB  1 
ATOM   1783  C CG  . TYR A 1 266 ? 106.514 134.527 141.920 1.00 16.55  ? 231 TYR A CG  1 
ATOM   1784  C CD1 . TYR A 1 266 ? 106.404 135.841 142.348 1.00 18.60  ? 231 TYR A CD1 1 
ATOM   1785  C CD2 . TYR A 1 266 ? 106.665 134.291 140.561 1.00 19.65  ? 231 TYR A CD2 1 
ATOM   1786  C CE1 . TYR A 1 266 ? 106.442 136.887 141.454 1.00 18.90  ? 231 TYR A CE1 1 
ATOM   1787  C CE2 . TYR A 1 266 ? 106.702 135.333 139.658 1.00 19.97  ? 231 TYR A CE2 1 
ATOM   1788  C CZ  . TYR A 1 266 ? 106.592 136.629 140.111 1.00 19.26  ? 231 TYR A CZ  1 
ATOM   1789  O OH  . TYR A 1 266 ? 106.627 137.674 139.221 1.00 19.23  ? 231 TYR A OH  1 
ATOM   1790  N N   . LEU A 1 267 ? 107.443 131.143 144.876 1.00 14.75  ? 232 LEU A N   1 
ATOM   1791  C CA  . LEU A 1 267 ? 107.183 130.326 146.061 1.00 13.26  ? 232 LEU A CA  1 
ATOM   1792  C C   . LEU A 1 267 ? 108.312 130.399 147.080 1.00 13.64  ? 232 LEU A C   1 
ATOM   1793  O O   . LEU A 1 267 ? 108.020 130.628 148.267 1.00 14.52  ? 232 LEU A O   1 
ATOM   1794  C CB  . LEU A 1 267 ? 106.875 128.878 145.662 1.00 12.42  ? 232 LEU A CB  1 
ATOM   1795  C CG  . LEU A 1 267 ? 105.459 128.596 145.162 1.00 12.28  ? 232 LEU A CG  1 
ATOM   1796  C CD1 . LEU A 1 267 ? 105.301 127.124 144.829 1.00 14.56  ? 232 LEU A CD1 1 
ATOM   1797  C CD2 . LEU A 1 267 ? 104.439 129.023 146.202 1.00 9.42   ? 232 LEU A CD2 1 
ATOM   1798  N N   . PRO A 1 268 ? 109.588 130.192 146.725 1.00 12.69  ? 233 PRO A N   1 
ATOM   1799  C CA  . PRO A 1 268 ? 110.636 130.376 147.743 1.00 12.30  ? 233 PRO A CA  1 
ATOM   1800  C C   . PRO A 1 268 ? 110.640 131.763 148.358 1.00 11.08  ? 233 PRO A C   1 
ATOM   1801  O O   . PRO A 1 268 ? 110.875 131.897 149.564 1.00 12.61  ? 233 PRO A O   1 
ATOM   1802  C CB  . PRO A 1 268 ? 111.929 130.105 146.963 1.00 12.10  ? 233 PRO A CB  1 
ATOM   1803  C CG  . PRO A 1 268 ? 111.526 129.229 145.853 1.00 13.29  ? 233 PRO A CG  1 
ATOM   1804  C CD  . PRO A 1 268 ? 110.143 129.657 145.468 1.00 13.17  ? 233 PRO A CD  1 
ATOM   1805  N N   . CYS A 1 269 ? 110.400 132.807 147.560 1.00 10.71  ? 234 CYS A N   1 
ATOM   1806  C CA  . CYS A 1 269 ? 110.369 134.154 148.117 1.00 9.49   ? 234 CYS A CA  1 
ATOM   1807  C C   . CYS A 1 269 ? 109.185 134.344 149.056 1.00 10.46  ? 234 CYS A C   1 
ATOM   1808  O O   . CYS A 1 269 ? 109.320 134.974 150.110 1.00 10.90  ? 234 CYS A O   1 
ATOM   1809  C CB  . CYS A 1 269 ? 110.337 135.191 146.996 1.00 9.70   ? 234 CYS A CB  1 
ATOM   1810  S SG  . CYS A 1 269 ? 111.892 135.356 146.092 1.00 15.69  ? 234 CYS A SG  1 
ATOM   1811  N N   . ILE A 1 270 ? 108.014 133.815 148.690 1.00 11.81  ? 235 ILE A N   1 
ATOM   1812  C CA  . ILE A 1 270 ? 106.855 133.922 149.572 1.00 10.70  ? 235 ILE A CA  1 
ATOM   1813  C C   . ILE A 1 270 ? 107.092 133.151 150.862 1.00 10.90  ? 235 ILE A C   1 
ATOM   1814  O O   . ILE A 1 270 ? 106.804 133.643 151.960 1.00 11.65  ? 235 ILE A O   1 
ATOM   1815  C CB  . ILE A 1 270 ? 105.584 133.445 148.845 1.00 9.95   ? 235 ILE A CB  1 
ATOM   1816  C CG1 . ILE A 1 270 ? 105.161 134.467 147.790 1.00 11.41  ? 235 ILE A CG1 1 
ATOM   1817  C CG2 . ILE A 1 270 ? 104.458 133.206 149.832 1.00 8.08   ? 235 ILE A CG2 1 
ATOM   1818  C CD1 . ILE A 1 270 ? 104.237 133.911 146.736 1.00 11.60  ? 235 ILE A CD1 1 
ATOM   1819  N N   . MET A 1 271 ? 107.629 131.934 150.754 1.00 12.05  ? 236 MET A N   1 
ATOM   1820  C CA  . MET A 1 271 ? 107.883 131.136 151.948 1.00 11.00  ? 236 MET A CA  1 
ATOM   1821  C C   . MET A 1 271 ? 108.975 131.748 152.813 1.00 10.68  ? 236 MET A C   1 
ATOM   1822  O O   . MET A 1 271 ? 108.909 131.656 154.043 1.00 11.02  ? 236 MET A O   1 
ATOM   1823  C CB  . MET A 1 271 ? 108.215 129.700 151.557 1.00 11.38  ? 236 MET A CB  1 
ATOM   1824  C CG  . MET A 1 271 ? 106.969 128.880 151.271 1.00 14.61  ? 236 MET A CG  1 
ATOM   1825  S SD  . MET A 1 271 ? 107.290 127.135 151.000 1.00 43.25  ? 236 MET A SD  1 
ATOM   1826  C CE  . MET A 1 271 ? 107.849 127.197 149.306 1.00 20.21  ? 236 MET A CE  1 
ATOM   1827  N N   . THR A 1 272 ? 109.987 132.366 152.198 1.00 12.09  ? 237 THR A N   1 
ATOM   1828  C CA  . THR A 1 272 ? 111.006 133.046 152.988 1.00 10.76  ? 237 THR A CA  1 
ATOM   1829  C C   . THR A 1 272 ? 110.403 134.225 153.739 1.00 10.78  ? 237 THR A C   1 
ATOM   1830  O O   . THR A 1 272 ? 110.745 134.468 154.902 1.00 11.70  ? 237 THR A O   1 
ATOM   1831  C CB  . THR A 1 272 ? 112.158 133.503 152.094 1.00 10.23  ? 237 THR A CB  1 
ATOM   1832  O OG1 . THR A 1 272 ? 112.690 132.375 151.388 1.00 11.50  ? 237 THR A OG1 1 
ATOM   1833  C CG2 . THR A 1 272 ? 113.265 134.124 152.929 1.00 8.05   ? 237 THR A CG2 1 
ATOM   1834  N N   . VAL A 1 273 ? 109.510 134.975 153.087 1.00 11.23  ? 238 VAL A N   1 
ATOM   1835  C CA  . VAL A 1 273 ? 108.833 136.069 153.774 1.00 11.15  ? 238 VAL A CA  1 
ATOM   1836  C C   . VAL A 1 273 ? 107.961 135.517 154.889 1.00 12.22  ? 238 VAL A C   1 
ATOM   1837  O O   . VAL A 1 273 ? 107.950 136.043 156.009 1.00 12.84  ? 238 VAL A O   1 
ATOM   1838  C CB  . VAL A 1 273 ? 108.013 136.907 152.778 1.00 11.49  ? 238 VAL A CB  1 
ATOM   1839  C CG1 . VAL A 1 273 ? 107.143 137.906 153.520 1.00 11.39  ? 238 VAL A CG1 1 
ATOM   1840  C CG2 . VAL A 1 273 ? 108.933 137.622 151.814 1.00 12.34  ? 238 VAL A CG2 1 
ATOM   1841  N N   . ILE A 1 274 ? 107.205 134.455 154.596 1.00 12.33  ? 239 ILE A N   1 
ATOM   1842  C CA  . ILE A 1 274 ? 106.412 133.799 155.631 1.00 9.67   ? 239 ILE A CA  1 
ATOM   1843  C C   . ILE A 1 274 ? 107.318 133.339 156.761 1.00 10.98  ? 239 ILE A C   1 
ATOM   1844  O O   . ILE A 1 274 ? 106.995 133.500 157.943 1.00 12.82  ? 239 ILE A O   1 
ATOM   1845  C CB  . ILE A 1 274 ? 105.609 132.630 155.032 1.00 7.19   ? 239 ILE A CB  1 
ATOM   1846  C CG1 . ILE A 1 274 ? 104.475 133.154 154.153 1.00 7.87   ? 239 ILE A CG1 1 
ATOM   1847  C CG2 . ILE A 1 274 ? 105.059 131.738 156.130 1.00 6.32   ? 239 ILE A CG2 1 
ATOM   1848  C CD1 . ILE A 1 274 ? 103.829 132.087 153.305 1.00 9.15   ? 239 ILE A CD1 1 
ATOM   1849  N N   . LEU A 1 275 ? 108.484 132.788 156.413 1.00 11.84  ? 240 LEU A N   1 
ATOM   1850  C CA  . LEU A 1 275 ? 109.400 132.279 157.425 1.00 11.89  ? 240 LEU A CA  1 
ATOM   1851  C C   . LEU A 1 275 ? 109.956 133.411 158.276 1.00 13.74  ? 240 LEU A C   1 
ATOM   1852  O O   . LEU A 1 275 ? 110.239 133.214 159.462 1.00 15.83  ? 240 LEU A O   1 
ATOM   1853  C CB  . LEU A 1 275 ? 110.531 131.500 156.756 1.00 10.60  ? 240 LEU A CB  1 
ATOM   1854  C CG  . LEU A 1 275 ? 111.014 130.228 157.446 1.00 11.98  ? 240 LEU A CG  1 
ATOM   1855  C CD1 . LEU A 1 275 ? 109.830 129.395 157.901 1.00 14.15  ? 240 LEU A CD1 1 
ATOM   1856  C CD2 . LEU A 1 275 ? 111.891 129.433 156.497 1.00 10.52  ? 240 LEU A CD2 1 
ATOM   1857  N N   . SER A 1 276 ? 110.103 134.602 157.694 1.00 13.23  ? 241 SER A N   1 
ATOM   1858  C CA  . SER A 1 276 ? 110.581 135.746 158.458 1.00 12.00  ? 241 SER A CA  1 
ATOM   1859  C C   . SER A 1 276 ? 109.535 136.184 159.470 1.00 11.87  ? 241 SER A C   1 
ATOM   1860  O O   . SER A 1 276 ? 109.879 136.637 160.567 1.00 12.55  ? 241 SER A O   1 
ATOM   1861  C CB  . SER A 1 276 ? 110.944 136.895 157.520 1.00 11.75  ? 241 SER A CB  1 
ATOM   1862  O OG  . SER A 1 276 ? 109.832 137.278 156.733 1.00 12.27  ? 241 SER A OG  1 
ATOM   1863  N N   . GLN A 1 277 ? 108.257 136.039 159.117 1.00 14.17  ? 242 GLN A N   1 
ATOM   1864  C CA  . GLN A 1 277 ? 107.165 136.382 160.014 1.00 14.73  ? 242 GLN A CA  1 
ATOM   1865  C C   . GLN A 1 277 ? 106.981 135.318 161.084 1.00 15.45  ? 242 GLN A C   1 
ATOM   1866  O O   . GLN A 1 277 ? 106.440 135.608 162.156 1.00 18.37  ? 242 GLN A O   1 
ATOM   1867  C CB  . GLN A 1 277 ? 105.873 136.563 159.220 1.00 12.48  ? 242 GLN A CB  1 
ATOM   1868  C CG  . GLN A 1 277 ? 105.919 137.715 158.237 1.00 16.20  ? 242 GLN A CG  1 
ATOM   1869  C CD  . GLN A 1 277 ? 104.959 137.528 157.084 1.00 18.36  ? 242 GLN A CD  1 
ATOM   1870  O OE1 . GLN A 1 277 ? 105.014 138.252 156.092 1.00 19.80  ? 242 GLN A OE1 1 
ATOM   1871  N NE2 . GLN A 1 277 ? 104.072 136.548 157.207 1.00 15.81  ? 242 GLN A NE2 1 
ATOM   1872  N N   . VAL A 1 278 ? 107.408 134.083 160.803 1.00 14.95  ? 243 VAL A N   1 
ATOM   1873  C CA  . VAL A 1 278 ? 107.365 133.018 161.797 1.00 17.38  ? 243 VAL A CA  1 
ATOM   1874  C C   . VAL A 1 278 ? 108.170 133.388 163.036 1.00 18.11  ? 243 VAL A C   1 
ATOM   1875  O O   . VAL A 1 278 ? 107.933 132.839 164.118 1.00 19.54  ? 243 VAL A O   1 
ATOM   1876  C CB  . VAL A 1 278 ? 107.873 131.708 161.149 1.00 14.15  ? 243 VAL A CB  1 
ATOM   1877  C CG1 . VAL A 1 278 ? 108.005 130.602 162.159 1.00 12.51  ? 243 VAL A CG1 1 
ATOM   1878  C CG2 . VAL A 1 278 ? 106.932 131.267 160.045 1.00 14.69  ? 243 VAL A CG2 1 
ATOM   1879  N N   . SER A 1 279 ? 109.088 134.350 162.919 1.00 16.77  ? 244 SER A N   1 
ATOM   1880  C CA  . SER A 1 279 ? 109.824 134.810 164.090 1.00 18.50  ? 244 SER A CA  1 
ATOM   1881  C C   . SER A 1 279 ? 108.904 135.496 165.089 1.00 21.25  ? 244 SER A C   1 
ATOM   1882  O O   . SER A 1 279 ? 109.177 135.481 166.294 1.00 25.29  ? 244 SER A O   1 
ATOM   1883  C CB  . SER A 1 279 ? 110.949 135.755 163.670 1.00 19.32  ? 244 SER A CB  1 
ATOM   1884  O OG  . SER A 1 279 ? 111.625 136.279 164.799 1.00 16.61  ? 244 SER A OG  1 
ATOM   1885  N N   . PHE A 1 280 ? 107.818 136.108 164.607 1.00 21.17  ? 245 PHE A N   1 
ATOM   1886  C CA  . PHE A 1 280 ? 106.888 136.804 165.488 1.00 22.08  ? 245 PHE A CA  1 
ATOM   1887  C C   . PHE A 1 280 ? 106.223 135.865 166.485 1.00 22.66  ? 245 PHE A C   1 
ATOM   1888  O O   . PHE A 1 280 ? 105.699 136.330 167.502 1.00 25.03  ? 245 PHE A O   1 
ATOM   1889  C CB  . PHE A 1 280 ? 105.829 137.528 164.654 1.00 20.38  ? 245 PHE A CB  1 
ATOM   1890  C CG  . PHE A 1 280 ? 106.400 138.515 163.675 1.00 19.78  ? 245 PHE A CG  1 
ATOM   1891  C CD1 . PHE A 1 280 ? 107.638 139.096 163.892 1.00 20.86  ? 245 PHE A CD1 1 
ATOM   1892  C CD2 . PHE A 1 280 ? 105.709 138.843 162.523 1.00 21.31  ? 245 PHE A CD2 1 
ATOM   1893  C CE1 . PHE A 1 280 ? 108.167 139.996 162.989 1.00 21.51  ? 245 PHE A CE1 1 
ATOM   1894  C CE2 . PHE A 1 280 ? 106.235 139.741 161.614 1.00 22.86  ? 245 PHE A CE2 1 
ATOM   1895  C CZ  . PHE A 1 280 ? 107.465 140.318 161.848 1.00 22.61  ? 245 PHE A CZ  1 
ATOM   1896  N N   . TRP A 1 281 ? 106.224 134.561 166.216 1.00 19.61  ? 246 TRP A N   1 
ATOM   1897  C CA  . TRP A 1 281 ? 105.565 133.588 167.076 1.00 19.83  ? 246 TRP A CA  1 
ATOM   1898  C C   . TRP A 1 281 ? 106.519 132.950 168.076 1.00 20.70  ? 246 TRP A C   1 
ATOM   1899  O O   . TRP A 1 281 ? 106.085 132.124 168.885 1.00 25.71  ? 246 TRP A O   1 
ATOM   1900  C CB  . TRP A 1 281 ? 104.906 132.495 166.229 1.00 20.17  ? 246 TRP A CB  1 
ATOM   1901  C CG  . TRP A 1 281 ? 103.880 133.008 165.268 1.00 23.13  ? 246 TRP A CG  1 
ATOM   1902  C CD1 . TRP A 1 281 ? 104.099 133.479 164.007 1.00 21.94  ? 246 TRP A CD1 1 
ATOM   1903  C CD2 . TRP A 1 281 ? 102.467 133.083 165.485 1.00 26.55  ? 246 TRP A CD2 1 
ATOM   1904  N NE1 . TRP A 1 281 ? 102.910 133.855 163.429 1.00 23.19  ? 246 TRP A NE1 1 
ATOM   1905  C CE2 . TRP A 1 281 ? 101.893 133.621 164.316 1.00 27.61  ? 246 TRP A CE2 1 
ATOM   1906  C CE3 . TRP A 1 281 ? 101.632 132.754 166.557 1.00 24.36  ? 246 TRP A CE3 1 
ATOM   1907  C CZ2 . TRP A 1 281 ? 100.523 133.836 164.189 1.00 28.51  ? 246 TRP A CZ2 1 
ATOM   1908  C CZ3 . TRP A 1 281 ? 100.273 132.968 166.428 1.00 23.94  ? 246 TRP A CZ3 1 
ATOM   1909  C CH2 . TRP A 1 281 ? 99.732  133.503 165.253 1.00 24.48  ? 246 TRP A CH2 1 
ATOM   1910  N N   . LEU A 1 282 ? 107.797 133.312 168.041 1.00 18.97  ? 247 LEU A N   1 
ATOM   1911  C CA  . LEU A 1 282 ? 108.764 132.865 169.030 1.00 21.76  ? 247 LEU A CA  1 
ATOM   1912  C C   . LEU A 1 282 ? 108.771 133.812 170.221 1.00 24.81  ? 247 LEU A C   1 
ATOM   1913  O O   . LEU A 1 282 ? 108.463 135.000 170.096 1.00 24.62  ? 247 LEU A O   1 
ATOM   1914  C CB  . LEU A 1 282 ? 110.162 132.780 168.416 1.00 21.03  ? 247 LEU A CB  1 
ATOM   1915  C CG  . LEU A 1 282 ? 110.293 131.889 167.180 1.00 17.41  ? 247 LEU A CG  1 
ATOM   1916  C CD1 . LEU A 1 282 ? 111.698 131.957 166.615 1.00 16.87  ? 247 LEU A CD1 1 
ATOM   1917  C CD2 . LEU A 1 282 ? 109.921 130.455 167.512 1.00 19.08  ? 247 LEU A CD2 1 
ATOM   1918  N N   . ASN A 1 283 ? 109.130 133.276 171.384 1.00 29.76  ? 248 ASN A N   1 
ATOM   1919  C CA  . ASN A 1 283 ? 109.146 134.082 172.595 1.00 36.64  ? 248 ASN A CA  1 
ATOM   1920  C C   . ASN A 1 283 ? 110.207 135.171 172.496 1.00 42.57  ? 248 ASN A C   1 
ATOM   1921  O O   . ASN A 1 283 ? 111.271 134.983 171.901 1.00 42.77  ? 248 ASN A O   1 
ATOM   1922  C CB  . ASN A 1 283 ? 109.406 133.207 173.821 1.00 43.87  ? 248 ASN A CB  1 
ATOM   1923  C CG  . ASN A 1 283 ? 110.713 132.450 173.729 1.00 43.42  ? 248 ASN A CG  1 
ATOM   1924  O OD1 . ASN A 1 283 ? 111.061 131.916 172.676 1.00 38.71  ? 248 ASN A OD1 1 
ATOM   1925  N ND2 . ASN A 1 283 ? 111.449 132.404 174.833 1.00 46.12  ? 248 ASN A ND2 1 
ATOM   1926  N N   . ARG A 1 284 ? 109.900 136.328 173.088 1.00 48.68  ? 249 ARG A N   1 
ATOM   1927  C CA  . ARG A 1 284 ? 110.775 137.487 172.964 1.00 49.08  ? 249 ARG A CA  1 
ATOM   1928  C C   . ARG A 1 284 ? 112.119 137.283 173.651 1.00 49.62  ? 249 ARG A C   1 
ATOM   1929  O O   . ARG A 1 284 ? 113.082 137.980 173.318 1.00 48.45  ? 249 ARG A O   1 
ATOM   1930  C CB  . ARG A 1 284 ? 110.086 138.724 173.539 1.00 48.85  ? 249 ARG A CB  1 
ATOM   1931  C CG  . ARG A 1 284 ? 109.837 138.643 175.035 1.00 56.82  ? 249 ARG A CG  1 
ATOM   1932  C CD  . ARG A 1 284 ? 108.821 139.673 175.496 1.00 61.52  ? 249 ARG A CD  1 
ATOM   1933  N NE  . ARG A 1 284 ? 109.167 141.024 175.075 1.00 61.14  ? 249 ARG A NE  1 
ATOM   1934  C CZ  . ARG A 1 284 ? 108.420 142.094 175.313 1.00 64.05  ? 249 ARG A CZ  1 
ATOM   1935  N NH1 . ARG A 1 284 ? 107.276 142.006 175.970 1.00 75.30  ? 249 ARG A NH1 1 
ATOM   1936  N NH2 . ARG A 1 284 ? 108.830 143.282 174.878 1.00 57.49  ? 249 ARG A NH2 1 
ATOM   1937  N N   . GLU A 1 285 ? 112.209 136.349 174.596 1.00 48.22  ? 250 GLU A N   1 
ATOM   1938  C CA  . GLU A 1 285 ? 113.442 136.160 175.348 1.00 47.37  ? 250 GLU A CA  1 
ATOM   1939  C C   . GLU A 1 285 ? 114.494 135.371 174.584 1.00 44.36  ? 250 GLU A C   1 
ATOM   1940  O O   . GLU A 1 285 ? 115.656 135.358 175.003 1.00 52.26  ? 250 GLU A O   1 
ATOM   1941  C CB  . GLU A 1 285 ? 113.150 135.455 176.676 1.00 58.96  ? 250 GLU A CB  1 
ATOM   1942  C CG  . GLU A 1 285 ? 112.141 136.165 177.569 1.00 71.21  ? 250 GLU A CG  1 
ATOM   1943  C CD  . GLU A 1 285 ? 110.705 135.874 177.182 1.00 70.35  ? 250 GLU A CD  1 
ATOM   1944  O OE1 . GLU A 1 285 ? 110.475 134.884 176.457 1.00 61.42  ? 250 GLU A OE1 1 
ATOM   1945  O OE2 . GLU A 1 285 ? 109.806 136.631 177.606 1.00 74.64  ? 250 GLU A OE2 1 
ATOM   1946  N N   . SER A 1 286 ? 114.124 134.714 173.485 1.00 40.99  ? 251 SER A N   1 
ATOM   1947  C CA  . SER A 1 286 ? 115.085 133.971 172.670 1.00 38.14  ? 251 SER A CA  1 
ATOM   1948  C C   . SER A 1 286 ? 115.722 134.908 171.645 1.00 29.55  ? 251 SER A C   1 
ATOM   1949  O O   . SER A 1 286 ? 115.467 134.841 170.441 1.00 28.93  ? 251 SER A O   1 
ATOM   1950  C CB  . SER A 1 286 ? 114.409 132.783 172.001 1.00 38.10  ? 251 SER A CB  1 
ATOM   1951  O OG  . SER A 1 286 ? 113.332 133.204 171.183 1.00 37.37  ? 251 SER A OG  1 
ATOM   1952  N N   . VAL A 1 287 ? 116.563 135.811 172.155 1.00 29.67  ? 252 VAL A N   1 
ATOM   1953  C CA  . VAL A 1 287 ? 117.191 136.807 171.285 1.00 29.94  ? 252 VAL A CA  1 
ATOM   1954  C C   . VAL A 1 287 ? 118.126 136.170 170.262 1.00 27.77  ? 252 VAL A C   1 
ATOM   1955  O O   . VAL A 1 287 ? 118.022 136.509 169.072 1.00 22.98  ? 252 VAL A O   1 
ATOM   1956  C CB  . VAL A 1 287 ? 117.888 137.885 172.134 1.00 26.94  ? 252 VAL A CB  1 
ATOM   1957  C CG1 . VAL A 1 287 ? 118.316 139.049 171.258 1.00 25.64  ? 252 VAL A CG1 1 
ATOM   1958  C CG2 . VAL A 1 287 ? 116.970 138.357 173.245 1.00 31.81  ? 252 VAL A CG2 1 
ATOM   1959  N N   . PRO A 1 288 ? 119.050 135.270 170.633 1.00 29.60  ? 253 PRO A N   1 
ATOM   1960  C CA  . PRO A 1 288 ? 119.923 134.679 169.604 1.00 22.01  ? 253 PRO A CA  1 
ATOM   1961  C C   . PRO A 1 288 ? 119.164 133.901 168.547 1.00 19.61  ? 253 PRO A C   1 
ATOM   1962  O O   . PRO A 1 288 ? 119.581 133.888 167.384 1.00 17.47  ? 253 PRO A O   1 
ATOM   1963  C CB  . PRO A 1 288 ? 120.864 133.772 170.409 1.00 22.78  ? 253 PRO A CB  1 
ATOM   1964  C CG  . PRO A 1 288 ? 120.770 134.247 171.808 1.00 28.73  ? 253 PRO A CG  1 
ATOM   1965  C CD  . PRO A 1 288 ? 119.384 134.761 171.976 1.00 32.54  ? 253 PRO A CD  1 
ATOM   1966  N N   . ALA A 1 289 ? 118.057 133.252 168.916 1.00 23.58  ? 254 ALA A N   1 
ATOM   1967  C CA  . ALA A 1 289 ? 117.313 132.454 167.949 1.00 20.33  ? 254 ALA A CA  1 
ATOM   1968  C C   . ALA A 1 289 ? 116.558 133.335 166.964 1.00 17.62  ? 254 ALA A C   1 
ATOM   1969  O O   . ALA A 1 289 ? 116.529 133.046 165.762 1.00 15.55  ? 254 ALA A O   1 
ATOM   1970  C CB  . ALA A 1 289 ? 116.350 131.514 168.671 1.00 23.99  ? 254 ALA A CB  1 
ATOM   1971  N N   . ARG A 1 290 ? 115.939 134.414 167.449 1.00 19.13  ? 255 ARG A N   1 
ATOM   1972  C CA  . ARG A 1 290 ? 115.193 135.299 166.564 1.00 17.69  ? 255 ARG A CA  1 
ATOM   1973  C C   . ARG A 1 290 ? 116.094 136.250 165.791 1.00 20.32  ? 255 ARG A C   1 
ATOM   1974  O O   . ARG A 1 290 ? 115.686 136.744 164.735 1.00 21.54  ? 255 ARG A O   1 
ATOM   1975  C CB  . ARG A 1 290 ? 114.166 136.111 167.355 1.00 20.81  ? 255 ARG A CB  1 
ATOM   1976  C CG  . ARG A 1 290 ? 113.036 135.292 167.942 1.00 21.84  ? 255 ARG A CG  1 
ATOM   1977  C CD  . ARG A 1 290 ? 112.029 136.182 168.653 1.00 25.42  ? 255 ARG A CD  1 
ATOM   1978  N NE  . ARG A 1 290 ? 111.449 137.164 167.746 1.00 25.44  ? 255 ARG A NE  1 
ATOM   1979  C CZ  . ARG A 1 290 ? 110.333 137.839 167.983 1.00 25.65  ? 255 ARG A CZ  1 
ATOM   1980  N NH1 . ARG A 1 290 ? 109.622 137.634 169.079 1.00 25.53  ? 255 ARG A NH1 1 
ATOM   1981  N NH2 . ARG A 1 290 ? 109.908 138.725 167.088 1.00 25.85  ? 255 ARG A NH2 1 
ATOM   1982  N N   . THR A 1 291 ? 117.304 136.519 166.287 1.00 19.94  ? 256 THR A N   1 
ATOM   1983  C CA  . THR A 1 291 ? 118.271 137.267 165.491 1.00 17.53  ? 256 THR A CA  1 
ATOM   1984  C C   . THR A 1 291 ? 118.822 136.411 164.360 1.00 14.28  ? 256 THR A C   1 
ATOM   1985  O O   . THR A 1 291 ? 118.915 136.868 163.217 1.00 13.22  ? 256 THR A O   1 
ATOM   1986  C CB  . THR A 1 291 ? 119.405 137.780 166.375 1.00 18.78  ? 256 THR A CB  1 
ATOM   1987  O OG1 . THR A 1 291 ? 118.859 138.563 167.443 1.00 22.32  ? 256 THR A OG1 1 
ATOM   1988  C CG2 . THR A 1 291 ? 120.359 138.640 165.565 1.00 14.32  ? 256 THR A CG2 1 
ATOM   1989  N N   . VAL A 1 292 ? 119.176 135.159 164.654 1.00 14.10  ? 257 VAL A N   1 
ATOM   1990  C CA  . VAL A 1 292 ? 119.631 134.257 163.603 1.00 11.75  ? 257 VAL A CA  1 
ATOM   1991  C C   . VAL A 1 292 ? 118.509 134.017 162.603 1.00 11.37  ? 257 VAL A C   1 
ATOM   1992  O O   . VAL A 1 292 ? 118.733 133.993 161.388 1.00 10.63  ? 257 VAL A O   1 
ATOM   1993  C CB  . VAL A 1 292 ? 120.148 132.940 164.210 1.00 12.79  ? 257 VAL A CB  1 
ATOM   1994  C CG1 . VAL A 1 292 ? 120.330 131.889 163.128 1.00 13.45  ? 257 VAL A CG1 1 
ATOM   1995  C CG2 . VAL A 1 292 ? 121.457 133.178 164.940 1.00 13.58  ? 257 VAL A CG2 1 
ATOM   1996  N N   . PHE A 1 293 ? 117.287 133.823 163.103 1.00 13.03  ? 258 PHE A N   1 
ATOM   1997  C CA  . PHE A 1 293 ? 116.137 133.631 162.225 1.00 12.76  ? 258 PHE A CA  1 
ATOM   1998  C C   . PHE A 1 293 ? 116.001 134.785 161.238 1.00 12.60  ? 258 PHE A C   1 
ATOM   1999  O O   . PHE A 1 293 ? 115.901 134.571 160.026 1.00 13.58  ? 258 PHE A O   1 
ATOM   2000  C CB  . PHE A 1 293 ? 114.863 133.497 163.060 1.00 13.00  ? 258 PHE A CB  1 
ATOM   2001  C CG  . PHE A 1 293 ? 113.815 132.620 162.440 1.00 12.46  ? 258 PHE A CG  1 
ATOM   2002  C CD1 . PHE A 1 293 ? 113.635 132.587 161.071 1.00 12.79  ? 258 PHE A CD1 1 
ATOM   2003  C CD2 . PHE A 1 293 ? 112.995 131.840 163.236 1.00 15.21  ? 258 PHE A CD2 1 
ATOM   2004  C CE1 . PHE A 1 293 ? 112.673 131.780 160.506 1.00 16.09  ? 258 PHE A CE1 1 
ATOM   2005  C CE2 . PHE A 1 293 ? 112.027 131.034 162.677 1.00 16.68  ? 258 PHE A CE2 1 
ATOM   2006  C CZ  . PHE A 1 293 ? 111.863 131.006 161.311 1.00 18.59  ? 258 PHE A CZ  1 
ATOM   2007  N N   . GLY A 1 294 ? 116.021 136.021 161.739 1.00 10.50  ? 259 GLY A N   1 
ATOM   2008  C CA  . GLY A 1 294 ? 115.779 137.163 160.873 1.00 9.06   ? 259 GLY A CA  1 
ATOM   2009  C C   . GLY A 1 294 ? 116.930 137.470 159.935 1.00 10.06  ? 259 GLY A C   1 
ATOM   2010  O O   . GLY A 1 294 ? 116.716 137.781 158.760 1.00 9.92   ? 259 GLY A O   1 
ATOM   2011  N N   . VAL A 1 295 ? 118.165 137.384 160.433 1.00 10.64  ? 260 VAL A N   1 
ATOM   2012  C CA  . VAL A 1 295 ? 119.322 137.744 159.617 1.00 8.16   ? 260 VAL A CA  1 
ATOM   2013  C C   . VAL A 1 295 ? 119.562 136.709 158.526 1.00 8.07   ? 260 VAL A C   1 
ATOM   2014  O O   . VAL A 1 295 ? 119.938 137.053 157.400 1.00 8.99   ? 260 VAL A O   1 
ATOM   2015  C CB  . VAL A 1 295 ? 120.570 137.936 160.495 1.00 6.76   ? 260 VAL A CB  1 
ATOM   2016  C CG1 . VAL A 1 295 ? 121.742 138.345 159.638 1.00 6.57   ? 260 VAL A CG1 1 
ATOM   2017  C CG2 . VAL A 1 295 ? 120.316 138.994 161.538 1.00 9.35   ? 260 VAL A CG2 1 
ATOM   2018  N N   . THR A 1 296 ? 119.339 135.430 158.829 1.00 7.97   ? 261 THR A N   1 
ATOM   2019  C CA  . THR A 1 296 ? 119.567 134.398 157.826 1.00 6.69   ? 261 THR A CA  1 
ATOM   2020  C C   . THR A 1 296 ? 118.446 134.355 156.795 1.00 7.22   ? 261 THR A C   1 
ATOM   2021  O O   . THR A 1 296 ? 118.686 133.965 155.647 1.00 8.25   ? 261 THR A O   1 
ATOM   2022  C CB  . THR A 1 296 ? 119.728 133.034 158.499 1.00 6.34   ? 261 THR A CB  1 
ATOM   2023  O OG1 . THR A 1 296 ? 120.741 133.120 159.507 1.00 10.26  ? 261 THR A OG1 1 
ATOM   2024  C CG2 . THR A 1 296 ? 120.150 131.984 157.487 1.00 4.40   ? 261 THR A CG2 1 
ATOM   2025  N N   . THR A 1 297 ? 117.231 134.770 157.162 1.00 7.33   ? 262 THR A N   1 
ATOM   2026  C CA  . THR A 1 297 ? 116.205 134.940 156.139 1.00 7.86   ? 262 THR A CA  1 
ATOM   2027  C C   . THR A 1 297 ? 116.562 136.080 155.198 1.00 7.76   ? 262 THR A C   1 
ATOM   2028  O O   . THR A 1 297 ? 116.218 136.032 154.012 1.00 8.00   ? 262 THR A O   1 
ATOM   2029  C CB  . THR A 1 297 ? 114.835 135.188 156.772 1.00 6.88   ? 262 THR A CB  1 
ATOM   2030  O OG1 . THR A 1 297 ? 114.924 136.268 157.708 1.00 6.75   ? 262 THR A OG1 1 
ATOM   2031  C CG2 . THR A 1 297 ? 114.319 133.934 157.463 1.00 7.64   ? 262 THR A CG2 1 
ATOM   2032  N N   . VAL A 1 298 ? 117.238 137.114 155.706 1.00 7.11   ? 263 VAL A N   1 
ATOM   2033  C CA  . VAL A 1 298 ? 117.725 138.174 154.830 1.00 7.08   ? 263 VAL A CA  1 
ATOM   2034  C C   . VAL A 1 298 ? 118.765 137.614 153.871 1.00 8.36   ? 263 VAL A C   1 
ATOM   2035  O O   . VAL A 1 298 ? 118.760 137.922 152.673 1.00 9.83   ? 263 VAL A O   1 
ATOM   2036  C CB  . VAL A 1 298 ? 118.288 139.342 155.661 1.00 6.74   ? 263 VAL A CB  1 
ATOM   2037  C CG1 . VAL A 1 298 ? 119.010 140.320 154.766 1.00 7.51   ? 263 VAL A CG1 1 
ATOM   2038  C CG2 . VAL A 1 298 ? 117.180 140.043 156.419 1.00 7.32   ? 263 VAL A CG2 1 
ATOM   2039  N N   . LEU A 1 299 ? 119.674 136.779 154.383 1.00 7.00   ? 264 LEU A N   1 
ATOM   2040  C CA  . LEU A 1 299 ? 120.683 136.165 153.527 1.00 6.16   ? 264 LEU A CA  1 
ATOM   2041  C C   . LEU A 1 299 ? 120.059 135.190 152.540 1.00 6.95   ? 264 LEU A C   1 
ATOM   2042  O O   . LEU A 1 299 ? 120.568 135.028 151.425 1.00 7.99   ? 264 LEU A O   1 
ATOM   2043  C CB  . LEU A 1 299 ? 121.728 135.451 154.381 1.00 4.89   ? 264 LEU A CB  1 
ATOM   2044  C CG  . LEU A 1 299 ? 122.879 134.759 153.650 1.00 3.60   ? 264 LEU A CG  1 
ATOM   2045  C CD1 . LEU A 1 299 ? 123.597 135.716 152.719 1.00 3.29   ? 264 LEU A CD1 1 
ATOM   2046  C CD2 . LEU A 1 299 ? 123.842 134.145 154.648 1.00 2.65   ? 264 LEU A CD2 1 
ATOM   2047  N N   . THR A 1 300 ? 118.958 134.542 152.924 1.00 7.00   ? 265 THR A N   1 
ATOM   2048  C CA  . THR A 1 300 ? 118.256 133.668 151.992 1.00 7.19   ? 265 THR A CA  1 
ATOM   2049  C C   . THR A 1 300 ? 117.595 134.476 150.885 1.00 9.52   ? 265 THR A C   1 
ATOM   2050  O O   . THR A 1 300 ? 117.618 134.073 149.716 1.00 10.66  ? 265 THR A O   1 
ATOM   2051  C CB  . THR A 1 300 ? 117.224 132.823 152.734 1.00 6.06   ? 265 THR A CB  1 
ATOM   2052  O OG1 . THR A 1 300 ? 117.870 132.091 153.780 1.00 5.11   ? 265 THR A OG1 1 
ATOM   2053  C CG2 . THR A 1 300 ? 116.553 131.846 151.785 1.00 7.99   ? 265 THR A CG2 1 
ATOM   2054  N N   . MET A 1 301 ? 116.999 135.619 151.235 1.00 9.66   ? 266 MET A N   1 
ATOM   2055  C CA  . MET A 1 301 ? 116.414 136.482 150.216 1.00 8.96   ? 266 MET A CA  1 
ATOM   2056  C C   . MET A 1 301 ? 117.487 137.023 149.283 1.00 11.68  ? 266 MET A C   1 
ATOM   2057  O O   . MET A 1 301 ? 117.275 137.117 148.070 1.00 14.82  ? 266 MET A O   1 
ATOM   2058  C CB  . MET A 1 301 ? 115.649 137.632 150.874 1.00 8.92   ? 266 MET A CB  1 
ATOM   2059  C CG  . MET A 1 301 ? 114.218 137.306 151.271 1.00 10.64  ? 266 MET A CG  1 
ATOM   2060  S SD  . MET A 1 301 ? 113.191 136.681 149.927 1.00 14.06  ? 266 MET A SD  1 
ATOM   2061  C CE  . MET A 1 301 ? 113.512 137.888 148.645 1.00 11.84  ? 266 MET A CE  1 
ATOM   2062  N N   . THR A 1 302 ? 118.649 137.384 149.835 1.00 10.75  ? 267 THR A N   1 
ATOM   2063  C CA  . THR A 1 302 ? 119.747 137.867 149.004 1.00 10.56  ? 267 THR A CA  1 
ATOM   2064  C C   . THR A 1 302 ? 120.207 136.793 148.027 1.00 13.33  ? 267 THR A C   1 
ATOM   2065  O O   . THR A 1 302 ? 120.477 137.083 146.856 1.00 16.70  ? 267 THR A O   1 
ATOM   2066  C CB  . THR A 1 302 ? 120.908 138.328 149.883 1.00 9.00   ? 267 THR A CB  1 
ATOM   2067  O OG1 . THR A 1 302 ? 120.431 139.281 150.840 1.00 9.96   ? 267 THR A OG1 1 
ATOM   2068  C CG2 . THR A 1 302 ? 121.990 138.970 149.040 1.00 9.87   ? 267 THR A CG2 1 
ATOM   2069  N N   . THR A 1 303 ? 120.304 135.546 148.493 1.00 12.69  ? 268 THR A N   1 
ATOM   2070  C CA  . THR A 1 303 ? 120.676 134.448 147.607 1.00 11.50  ? 268 THR A CA  1 
ATOM   2071  C C   . THR A 1 303 ? 119.627 134.255 146.520 1.00 13.05  ? 268 THR A C   1 
ATOM   2072  O O   . THR A 1 303 ? 119.959 134.096 145.340 1.00 17.00  ? 268 THR A O   1 
ATOM   2073  C CB  . THR A 1 303 ? 120.873 133.164 148.410 1.00 9.62   ? 268 THR A CB  1 
ATOM   2074  O OG1 . THR A 1 303 ? 121.840 133.390 149.442 1.00 10.90  ? 268 THR A OG1 1 
ATOM   2075  C CG2 . THR A 1 303 ? 121.362 132.045 147.511 1.00 10.81  ? 268 THR A CG2 1 
ATOM   2076  N N   . LEU A 1 304 ? 118.348 134.249 146.905 1.00 12.44  ? 269 LEU A N   1 
ATOM   2077  C CA  . LEU A 1 304 ? 117.284 134.121 145.916 1.00 14.61  ? 269 LEU A CA  1 
ATOM   2078  C C   . LEU A 1 304 ? 117.247 135.327 144.988 1.00 21.38  ? 269 LEU A C   1 
ATOM   2079  O O   . LEU A 1 304 ? 117.078 135.177 143.772 1.00 28.41  ? 269 LEU A O   1 
ATOM   2080  C CB  . LEU A 1 304 ? 115.933 133.940 146.606 1.00 11.28  ? 269 LEU A CB  1 
ATOM   2081  C CG  . LEU A 1 304 ? 115.669 132.584 147.258 1.00 11.38  ? 269 LEU A CG  1 
ATOM   2082  C CD1 . LEU A 1 304 ? 114.563 132.690 148.288 1.00 9.20   ? 269 LEU A CD1 1 
ATOM   2083  C CD2 . LEU A 1 304 ? 115.322 131.557 146.198 1.00 15.19  ? 269 LEU A CD2 1 
ATOM   2084  N N   . SER A 1 305 ? 117.395 136.535 145.541 1.00 19.37  ? 270 SER A N   1 
ATOM   2085  C CA  . SER A 1 305 ? 117.273 137.735 144.719 1.00 19.23  ? 270 SER A CA  1 
ATOM   2086  C C   . SER A 1 305 ? 118.389 137.811 143.688 1.00 22.90  ? 270 SER A C   1 
ATOM   2087  O O   . SER A 1 305 ? 118.147 138.171 142.530 1.00 26.85  ? 270 SER A O   1 
ATOM   2088  C CB  . SER A 1 305 ? 117.280 138.982 145.601 1.00 18.95  ? 270 SER A CB  1 
ATOM   2089  O OG  . SER A 1 305 ? 117.297 140.162 144.819 1.00 26.64  ? 270 SER A OG  1 
ATOM   2090  N N   . ILE A 1 306 ? 119.619 137.485 144.089 1.00 21.30  ? 271 ILE A N   1 
ATOM   2091  C CA  . ILE A 1 306 ? 120.738 137.541 143.153 1.00 25.27  ? 271 ILE A CA  1 
ATOM   2092  C C   . ILE A 1 306 ? 120.550 136.504 142.054 1.00 31.50  ? 271 ILE A C   1 
ATOM   2093  O O   . ILE A 1 306 ? 120.733 136.792 140.866 1.00 40.05  ? 271 ILE A O   1 
ATOM   2094  C CB  . ILE A 1 306 ? 122.072 137.358 143.896 1.00 20.78  ? 271 ILE A CB  1 
ATOM   2095  C CG1 . ILE A 1 306 ? 122.376 138.607 144.725 1.00 18.61  ? 271 ILE A CG1 1 
ATOM   2096  C CG2 . ILE A 1 306 ? 123.194 137.074 142.918 1.00 26.06  ? 271 ILE A CG2 1 
ATOM   2097  C CD1 . ILE A 1 306 ? 123.535 138.450 145.668 1.00 16.97  ? 271 ILE A CD1 1 
ATOM   2098  N N   . SER A 1 307 ? 120.174 135.280 142.435 1.00 27.37  ? 272 SER A N   1 
ATOM   2099  C CA  . SER A 1 307 ? 120.011 134.221 141.445 1.00 32.15  ? 272 SER A CA  1 
ATOM   2100  C C   . SER A 1 307 ? 118.900 134.570 140.465 1.00 39.98  ? 272 SER A C   1 
ATOM   2101  O O   . SER A 1 307 ? 118.993 134.268 139.270 1.00 47.73  ? 272 SER A O   1 
ATOM   2102  C CB  . SER A 1 307 ? 119.717 132.892 142.138 1.00 28.29  ? 272 SER A CB  1 
ATOM   2103  O OG  . SER A 1 307 ? 119.455 131.872 141.192 1.00 29.99  ? 272 SER A OG  1 
ATOM   2104  N N   . ALA A 1 308 ? 117.836 135.205 140.963 1.00 36.64  ? 273 ALA A N   1 
ATOM   2105  C CA  . ALA A 1 308 ? 116.702 135.561 140.118 1.00 36.23  ? 273 ALA A CA  1 
ATOM   2106  C C   . ALA A 1 308 ? 117.121 136.523 139.015 1.00 47.53  ? 273 ALA A C   1 
ATOM   2107  O O   . ALA A 1 308 ? 116.667 136.406 137.871 1.00 50.49  ? 273 ALA A O   1 
ATOM   2108  C CB  . ALA A 1 308 ? 115.584 136.168 140.965 1.00 26.96  ? 273 ALA A CB  1 
ATOM   2109  N N   . ARG A 1 309 ? 117.981 137.489 139.346 1.00 49.69  ? 274 ARG A N   1 
ATOM   2110  C CA  . ARG A 1 309 ? 118.451 138.441 138.346 1.00 53.54  ? 274 ARG A CA  1 
ATOM   2111  C C   . ARG A 1 309 ? 119.313 137.754 137.292 1.00 55.25  ? 274 ARG A C   1 
ATOM   2112  O O   . ARG A 1 309 ? 119.189 138.052 136.099 1.00 59.92  ? 274 ARG A O   1 
ATOM   2113  C CB  . ARG A 1 309 ? 119.217 139.575 139.034 1.00 54.91  ? 274 ARG A CB  1 
ATOM   2114  C CG  . ARG A 1 309 ? 120.077 140.451 138.125 1.00 59.98  ? 274 ARG A CG  1 
ATOM   2115  C CD  . ARG A 1 309 ? 119.291 140.991 136.932 1.00 62.67  ? 274 ARG A CD  1 
ATOM   2116  N NE  . ARG A 1 309 ? 118.042 141.627 137.331 1.00 58.67  ? 274 ARG A NE  1 
ATOM   2117  C CZ  . ARG A 1 309 ? 117.284 142.353 136.521 1.00 51.94  ? 274 ARG A CZ  1 
ATOM   2118  N NH1 . ARG A 1 309 ? 117.630 142.574 135.264 1.00 58.39  ? 274 ARG A NH1 1 
ATOM   2119  N NH2 . ARG A 1 309 ? 116.155 142.877 136.987 1.00 43.03  ? 274 ARG A NH2 1 
ATOM   2120  N N   . ASN A 1 310 ? 120.191 136.833 137.704 1.00 49.15  ? 275 ASN A N   1 
ATOM   2121  C CA  . ASN A 1 310 ? 121.056 136.172 136.729 1.00 57.27  ? 275 ASN A CA  1 
ATOM   2122  C C   . ASN A 1 310 ? 120.245 135.481 135.641 1.00 62.12  ? 275 ASN A C   1 
ATOM   2123  O O   . ASN A 1 310 ? 120.729 135.314 134.516 1.00 62.39  ? 275 ASN A O   1 
ATOM   2124  C CB  . ASN A 1 310 ? 121.984 135.178 137.426 1.00 49.58  ? 275 ASN A CB  1 
ATOM   2125  C CG  . ASN A 1 310 ? 122.847 135.834 138.484 1.00 52.09  ? 275 ASN A CG  1 
ATOM   2126  O OD1 . ASN A 1 310 ? 122.615 136.980 138.866 1.00 51.18  ? 275 ASN A OD1 1 
ATOM   2127  N ND2 . ASN A 1 310 ? 123.852 135.109 138.960 1.00 56.53  ? 275 ASN A ND2 1 
ATOM   2128  N N   . SER A 1 311 ? 119.013 135.073 135.952 1.00 57.67  ? 276 SER A N   1 
ATOM   2129  C CA  . SER A 1 311 ? 118.138 134.528 134.923 1.00 51.42  ? 276 SER A CA  1 
ATOM   2130  C C   . SER A 1 311 ? 117.548 135.631 134.056 1.00 53.48  ? 276 SER A C   1 
ATOM   2131  O O   . SER A 1 311 ? 117.246 135.398 132.881 1.00 55.32  ? 276 SER A O   1 
ATOM   2132  C CB  . SER A 1 311 ? 117.023 133.701 135.561 1.00 50.18  ? 276 SER A CB  1 
ATOM   2133  O OG  . SER A 1 311 ? 117.560 132.660 136.358 1.00 50.23  ? 276 SER A OG  1 
ATOM   2134  N N   . LEU A 1 312 ? 117.373 136.826 134.619 1.00 58.88  ? 277 LEU A N   1 
ATOM   2135  C CA  . LEU A 1 312 ? 116.795 137.935 133.879 1.00 61.02  ? 277 LEU A CA  1 
ATOM   2136  C C   . LEU A 1 312 ? 117.757 138.409 132.792 1.00 67.42  ? 277 LEU A C   1 
ATOM   2137  O O   . LEU A 1 312 ? 118.977 138.351 132.963 1.00 68.19  ? 277 LEU A O   1 
ATOM   2138  C CB  . LEU A 1 312 ? 116.477 139.101 134.811 1.00 55.80  ? 277 LEU A CB  1 
ATOM   2139  C CG  . LEU A 1 312 ? 115.047 139.274 135.316 1.00 57.27  ? 277 LEU A CG  1 
ATOM   2140  C CD1 . LEU A 1 312 ? 115.050 139.464 136.822 1.00 51.84  ? 277 LEU A CD1 1 
ATOM   2141  C CD2 . LEU A 1 312 ? 114.381 140.451 134.625 1.00 53.84  ? 277 LEU A CD2 1 
ATOM   2142  N N   . PRO A 1 313 ? 117.234 138.886 131.668 1.00 67.02  ? 278 PRO A N   1 
ATOM   2143  C CA  . PRO A 1 313 ? 118.096 139.559 130.693 1.00 65.69  ? 278 PRO A CA  1 
ATOM   2144  C C   . PRO A 1 313 ? 118.658 140.852 131.261 1.00 67.99  ? 278 PRO A C   1 
ATOM   2145  O O   . PRO A 1 313 ? 118.041 141.512 132.100 1.00 66.80  ? 278 PRO A O   1 
ATOM   2146  C CB  . PRO A 1 313 ? 117.155 139.831 129.514 1.00 60.43  ? 278 PRO A CB  1 
ATOM   2147  C CG  . PRO A 1 313 ? 115.788 139.808 130.106 1.00 59.45  ? 278 PRO A CG  1 
ATOM   2148  C CD  . PRO A 1 313 ? 115.833 138.817 131.223 1.00 59.54  ? 278 PRO A CD  1 
ATOM   2149  N N   . LYS A 1 314 ? 119.848 141.214 130.786 1.00 67.67  ? 279 LYS A N   1 
ATOM   2150  C CA  . LYS A 1 314 ? 120.582 142.331 131.368 1.00 64.99  ? 279 LYS A CA  1 
ATOM   2151  C C   . LYS A 1 314 ? 119.941 143.657 130.982 1.00 59.69  ? 279 LYS A C   1 
ATOM   2152  O O   . LYS A 1 314 ? 120.489 144.402 130.162 1.00 63.12  ? 279 LYS A O   1 
ATOM   2153  C CB  . LYS A 1 314 ? 122.049 142.299 130.936 1.00 67.98  ? 279 LYS A CB  1 
ATOM   2154  C CG  . LYS A 1 314 ? 122.835 141.122 131.492 1.00 68.36  ? 279 LYS A CG  1 
ATOM   2155  C CD  . LYS A 1 314 ? 124.296 141.194 131.076 1.00 70.12  ? 279 LYS A CD  1 
ATOM   2156  C CE  . LYS A 1 314 ? 125.102 140.058 131.682 1.00 62.98  ? 279 LYS A CE  1 
ATOM   2157  N NZ  . LYS A 1 314 ? 126.543 140.148 131.317 1.00 51.98  ? 279 LYS A NZ  1 
ATOM   2158  N N   . VAL A 1 315 ? 118.788 143.962 131.565 1.00 55.84  ? 280 VAL A N   1 
ATOM   2159  C CA  . VAL A 1 315 ? 118.133 145.240 131.359 1.00 57.39  ? 280 VAL A CA  1 
ATOM   2160  C C   . VAL A 1 315 ? 118.418 146.135 132.556 1.00 56.88  ? 280 VAL A C   1 
ATOM   2161  O O   . VAL A 1 315 ? 118.824 145.679 133.629 1.00 59.30  ? 280 VAL A O   1 
ATOM   2162  C CB  . VAL A 1 315 ? 116.612 145.080 131.141 1.00 52.19  ? 280 VAL A CB  1 
ATOM   2163  C CG1 . VAL A 1 315 ? 116.338 144.130 129.987 1.00 52.51  ? 280 VAL A CG1 1 
ATOM   2164  C CG2 . VAL A 1 315 ? 115.942 144.591 132.414 1.00 52.02  ? 280 VAL A CG2 1 
ATOM   2165  N N   . ALA A 1 316 ? 118.207 147.434 132.370 1.00 52.64  ? 281 ALA A N   1 
ATOM   2166  C CA  . ALA A 1 316 ? 118.462 148.425 133.406 1.00 50.95  ? 281 ALA A CA  1 
ATOM   2167  C C   . ALA A 1 316 ? 117.190 149.185 133.754 1.00 49.19  ? 281 ALA A C   1 
ATOM   2168  O O   . ALA A 1 316 ? 117.191 150.409 133.897 1.00 49.12  ? 281 ALA A O   1 
ATOM   2169  C CB  . ALA A 1 316 ? 119.566 149.389 132.984 1.00 53.96  ? 281 ALA A CB  1 
ATOM   2170  N N   . TYR A 1 317 ? 116.087 148.458 133.902 1.00 47.35  ? 282 TYR A N   1 
ATOM   2171  C CA  . TYR A 1 317 ? 114.861 149.007 134.459 1.00 41.80  ? 282 TYR A CA  1 
ATOM   2172  C C   . TYR A 1 317 ? 114.208 147.942 135.327 1.00 37.73  ? 282 TYR A C   1 
ATOM   2173  O O   . TYR A 1 317 ? 114.504 146.751 135.210 1.00 39.86  ? 282 TYR A O   1 
ATOM   2174  C CB  . TYR A 1 317 ? 113.900 149.492 133.365 1.00 40.43  ? 282 TYR A CB  1 
ATOM   2175  C CG  . TYR A 1 317 ? 113.779 148.560 132.182 1.00 44.30  ? 282 TYR A CG  1 
ATOM   2176  C CD1 . TYR A 1 317 ? 112.830 147.549 132.164 1.00 38.09  ? 282 TYR A CD1 1 
ATOM   2177  C CD2 . TYR A 1 317 ? 114.614 148.693 131.082 1.00 45.26  ? 282 TYR A CD2 1 
ATOM   2178  C CE1 . TYR A 1 317 ? 112.717 146.697 131.085 1.00 38.87  ? 282 TYR A CE1 1 
ATOM   2179  C CE2 . TYR A 1 317 ? 114.508 147.845 130.000 1.00 44.15  ? 282 TYR A CE2 1 
ATOM   2180  C CZ  . TYR A 1 317 ? 113.559 146.850 130.007 1.00 42.31  ? 282 TYR A CZ  1 
ATOM   2181  O OH  . TYR A 1 317 ? 113.450 146.005 128.928 1.00 46.90  ? 282 TYR A OH  1 
ATOM   2182  N N   . ALA A 1 318 ? 113.311 148.383 136.202 1.00 31.78  ? 283 ALA A N   1 
ATOM   2183  C CA  . ALA A 1 318 ? 112.667 147.478 137.143 1.00 27.35  ? 283 ALA A CA  1 
ATOM   2184  C C   . ALA A 1 318 ? 111.531 146.746 136.440 1.00 29.51  ? 283 ALA A C   1 
ATOM   2185  O O   . ALA A 1 318 ? 110.597 147.376 135.934 1.00 32.25  ? 283 ALA A O   1 
ATOM   2186  C CB  . ALA A 1 318 ? 112.151 148.247 138.356 1.00 27.04  ? 283 ALA A CB  1 
ATOM   2187  N N   . THR A 1 319 ? 111.612 145.419 136.410 1.00 28.53  ? 284 THR A N   1 
ATOM   2188  C CA  . THR A 1 319 ? 110.537 144.600 135.879 1.00 25.60  ? 284 THR A CA  1 
ATOM   2189  C C   . THR A 1 319 ? 109.516 144.310 136.975 1.00 27.17  ? 284 THR A C   1 
ATOM   2190  O O   . THR A 1 319 ? 109.642 144.767 138.113 1.00 27.38  ? 284 THR A O   1 
ATOM   2191  C CB  . THR A 1 319 ? 111.098 143.303 135.302 1.00 25.31  ? 284 THR A CB  1 
ATOM   2192  O OG1 . THR A 1 319 ? 111.514 142.448 136.373 1.00 25.58  ? 284 THR A OG1 1 
ATOM   2193  C CG2 . THR A 1 319 ? 112.296 143.591 134.412 1.00 27.84  ? 284 THR A CG2 1 
ATOM   2194  N N   . ALA A 1 320 ? 108.479 143.544 136.629 1.00 28.26  ? 285 ALA A N   1 
ATOM   2195  C CA  . ALA A 1 320 ? 107.491 143.161 137.632 1.00 24.44  ? 285 ALA A CA  1 
ATOM   2196  C C   . ALA A 1 320 ? 108.114 142.300 138.720 1.00 23.67  ? 285 ALA A C   1 
ATOM   2197  O O   . ALA A 1 320 ? 107.834 142.490 139.908 1.00 26.78  ? 285 ALA A O   1 
ATOM   2198  C CB  . ALA A 1 320 ? 106.324 142.430 136.972 1.00 23.94  ? 285 ALA A CB  1 
ATOM   2199  N N   . MET A 1 321 ? 108.961 141.343 138.333 1.00 22.68  ? 286 MET A N   1 
ATOM   2200  C CA  . MET A 1 321 ? 109.579 140.468 139.323 1.00 21.53  ? 286 MET A CA  1 
ATOM   2201  C C   . MET A 1 321 ? 110.550 141.233 140.212 1.00 24.01  ? 286 MET A C   1 
ATOM   2202  O O   . MET A 1 321 ? 110.759 140.853 141.369 1.00 24.69  ? 286 MET A O   1 
ATOM   2203  C CB  . MET A 1 321 ? 110.274 139.295 138.632 1.00 21.75  ? 286 MET A CB  1 
ATOM   2204  C CG  . MET A 1 321 ? 110.630 138.156 139.574 1.00 23.46  ? 286 MET A CG  1 
ATOM   2205  S SD  . MET A 1 321 ? 111.063 136.630 138.719 1.00 40.67  ? 286 MET A SD  1 
ATOM   2206  C CE  . MET A 1 321 ? 112.562 137.120 137.878 1.00 34.47  ? 286 MET A CE  1 
ATOM   2207  N N   . ASP A 1 322 ? 111.153 142.302 139.688 1.00 26.47  ? 287 ASP A N   1 
ATOM   2208  C CA  . ASP A 1 322 ? 112.040 143.129 140.500 1.00 24.13  ? 287 ASP A CA  1 
ATOM   2209  C C   . ASP A 1 322 ? 111.286 143.767 141.657 1.00 21.33  ? 287 ASP A C   1 
ATOM   2210  O O   . ASP A 1 322 ? 111.795 143.828 142.782 1.00 21.75  ? 287 ASP A O   1 
ATOM   2211  C CB  . ASP A 1 322 ? 112.699 144.200 139.634 1.00 27.81  ? 287 ASP A CB  1 
ATOM   2212  C CG  . ASP A 1 322 ? 113.775 143.636 138.731 1.00 37.35  ? 287 ASP A CG  1 
ATOM   2213  O OD1 . ASP A 1 322 ? 114.554 142.778 139.196 1.00 39.33  ? 287 ASP A OD1 1 
ATOM   2214  O OD2 . ASP A 1 322 ? 113.841 144.047 137.554 1.00 45.68  ? 287 ASP A OD2 1 
ATOM   2215  N N   . TRP A 1 323 ? 110.078 144.269 141.395 1.00 19.20  ? 288 TRP A N   1 
ATOM   2216  C CA  . TRP A 1 323 ? 109.298 144.897 142.455 1.00 17.90  ? 288 TRP A CA  1 
ATOM   2217  C C   . TRP A 1 323 ? 108.864 143.877 143.498 1.00 17.59  ? 288 TRP A C   1 
ATOM   2218  O O   . TRP A 1 323 ? 108.880 144.170 144.699 1.00 20.32  ? 288 TRP A O   1 
ATOM   2219  C CB  . TRP A 1 323 ? 108.089 145.619 141.865 1.00 21.70  ? 288 TRP A CB  1 
ATOM   2220  C CG  . TRP A 1 323 ? 108.464 146.836 141.086 1.00 26.13  ? 288 TRP A CG  1 
ATOM   2221  C CD1 . TRP A 1 323 ? 108.307 147.033 139.747 1.00 26.29  ? 288 TRP A CD1 1 
ATOM   2222  C CD2 . TRP A 1 323 ? 109.077 148.025 141.598 1.00 29.39  ? 288 TRP A CD2 1 
ATOM   2223  N NE1 . TRP A 1 323 ? 108.777 148.275 139.394 1.00 28.18  ? 288 TRP A NE1 1 
ATOM   2224  C CE2 . TRP A 1 323 ? 109.256 148.903 140.514 1.00 27.98  ? 288 TRP A CE2 1 
ATOM   2225  C CE3 . TRP A 1 323 ? 109.488 148.434 142.871 1.00 26.91  ? 288 TRP A CE3 1 
ATOM   2226  C CZ2 . TRP A 1 323 ? 109.827 150.163 140.661 1.00 26.01  ? 288 TRP A CZ2 1 
ATOM   2227  C CZ3 . TRP A 1 323 ? 110.054 149.685 143.014 1.00 25.78  ? 288 TRP A CZ3 1 
ATOM   2228  C CH2 . TRP A 1 323 ? 110.219 150.535 141.917 1.00 26.60  ? 288 TRP A CH2 1 
ATOM   2229  N N   . PHE A 1 324 ? 108.460 142.681 143.064 1.00 16.16  ? 289 PHE A N   1 
ATOM   2230  C CA  . PHE A 1 324 ? 108.050 141.660 144.023 1.00 15.19  ? 289 PHE A CA  1 
ATOM   2231  C C   . PHE A 1 324 ? 109.209 141.276 144.931 1.00 16.25  ? 289 PHE A C   1 
ATOM   2232  O O   . PHE A 1 324 ? 109.030 141.105 146.142 1.00 18.34  ? 289 PHE A O   1 
ATOM   2233  C CB  . PHE A 1 324 ? 107.514 140.432 143.289 1.00 15.23  ? 289 PHE A CB  1 
ATOM   2234  C CG  . PHE A 1 324 ? 106.836 139.436 144.187 1.00 16.66  ? 289 PHE A CG  1 
ATOM   2235  C CD1 . PHE A 1 324 ? 105.486 139.545 144.469 1.00 23.35  ? 289 PHE A CD1 1 
ATOM   2236  C CD2 . PHE A 1 324 ? 107.547 138.389 144.747 1.00 15.21  ? 289 PHE A CD2 1 
ATOM   2237  C CE1 . PHE A 1 324 ? 104.859 138.632 145.292 1.00 24.13  ? 289 PHE A CE1 1 
ATOM   2238  C CE2 . PHE A 1 324 ? 106.924 137.474 145.570 1.00 17.37  ? 289 PHE A CE2 1 
ATOM   2239  C CZ  . PHE A 1 324 ? 105.580 137.597 145.843 1.00 20.21  ? 289 PHE A CZ  1 
ATOM   2240  N N   . ILE A 1 325 ? 110.408 141.139 144.364 1.00 17.53  ? 290 ILE A N   1 
ATOM   2241  C CA  . ILE A 1 325 ? 111.569 140.789 145.172 1.00 16.78  ? 290 ILE A CA  1 
ATOM   2242  C C   . ILE A 1 325 ? 111.944 141.950 146.083 1.00 14.22  ? 290 ILE A C   1 
ATOM   2243  O O   . ILE A 1 325 ? 112.318 141.752 147.244 1.00 13.31  ? 290 ILE A O   1 
ATOM   2244  C CB  . ILE A 1 325 ? 112.739 140.367 144.265 1.00 17.31  ? 290 ILE A CB  1 
ATOM   2245  C CG1 . ILE A 1 325 ? 112.426 139.032 143.591 1.00 16.19  ? 290 ILE A CG1 1 
ATOM   2246  C CG2 . ILE A 1 325 ? 114.019 140.260 145.061 1.00 18.97  ? 290 ILE A CG2 1 
ATOM   2247  C CD1 . ILE A 1 325 ? 113.420 138.642 142.533 1.00 18.73  ? 290 ILE A CD1 1 
ATOM   2248  N N   . ALA A 1 326 ? 111.842 143.181 145.572 1.00 14.97  ? 291 ALA A N   1 
ATOM   2249  C CA  . ALA A 1 326 ? 112.161 144.350 146.384 1.00 12.48  ? 291 ALA A CA  1 
ATOM   2250  C C   . ALA A 1 326 ? 111.204 144.471 147.560 1.00 13.20  ? 291 ALA A C   1 
ATOM   2251  O O   . ALA A 1 326 ? 111.619 144.798 148.677 1.00 15.23  ? 291 ALA A O   1 
ATOM   2252  C CB  . ALA A 1 326 ? 112.129 145.614 145.527 1.00 12.86  ? 291 ALA A CB  1 
ATOM   2253  N N   . VAL A 1 327 ? 109.913 144.228 147.324 1.00 14.29  ? 292 VAL A N   1 
ATOM   2254  C CA  . VAL A 1 327 ? 108.939 144.333 148.404 1.00 15.09  ? 292 VAL A CA  1 
ATOM   2255  C C   . VAL A 1 327 ? 109.146 143.203 149.403 1.00 14.60  ? 292 VAL A C   1 
ATOM   2256  O O   . VAL A 1 327 ? 109.086 143.414 150.620 1.00 15.69  ? 292 VAL A O   1 
ATOM   2257  C CB  . VAL A 1 327 ? 107.508 144.349 147.842 1.00 14.91  ? 292 VAL A CB  1 
ATOM   2258  C CG1 . VAL A 1 327 ? 106.501 144.207 148.964 1.00 15.55  ? 292 VAL A CG1 1 
ATOM   2259  C CG2 . VAL A 1 327 ? 107.261 145.638 147.081 1.00 15.27  ? 292 VAL A CG2 1 
ATOM   2260  N N   . CYS A 1 328 ? 109.386 141.985 148.909 1.00 13.40  ? 293 CYS A N   1 
ATOM   2261  C CA  . CYS A 1 328 ? 109.707 140.883 149.808 1.00 14.30  ? 293 CYS A CA  1 
ATOM   2262  C C   . CYS A 1 328 ? 110.941 141.214 150.632 1.00 15.71  ? 293 CYS A C   1 
ATOM   2263  O O   . CYS A 1 328 ? 111.011 140.888 151.822 1.00 16.85  ? 293 CYS A O   1 
ATOM   2264  C CB  . CYS A 1 328 ? 109.916 139.593 149.017 1.00 14.08  ? 293 CYS A CB  1 
ATOM   2265  S SG  . CYS A 1 328 ? 108.410 138.884 148.324 1.00 20.02  ? 293 CYS A SG  1 
ATOM   2266  N N   . TYR A 1 329 ? 111.932 141.855 150.007 1.00 15.70  ? 294 TYR A N   1 
ATOM   2267  C CA  . TYR A 1 329 ? 113.118 142.278 150.741 1.00 12.03  ? 294 TYR A CA  1 
ATOM   2268  C C   . TYR A 1 329 ? 112.747 143.274 151.829 1.00 11.22  ? 294 TYR A C   1 
ATOM   2269  O O   . TYR A 1 329 ? 113.280 143.215 152.942 1.00 12.66  ? 294 TYR A O   1 
ATOM   2270  C CB  . TYR A 1 329 ? 114.146 142.881 149.786 1.00 13.14  ? 294 TYR A CB  1 
ATOM   2271  C CG  . TYR A 1 329 ? 115.576 142.583 150.164 1.00 13.55  ? 294 TYR A CG  1 
ATOM   2272  C CD1 . TYR A 1 329 ? 116.206 143.286 151.182 1.00 14.32  ? 294 TYR A CD1 1 
ATOM   2273  C CD2 . TYR A 1 329 ? 116.299 141.602 149.502 1.00 13.18  ? 294 TYR A CD2 1 
ATOM   2274  C CE1 . TYR A 1 329 ? 117.513 143.018 151.531 1.00 15.54  ? 294 TYR A CE1 1 
ATOM   2275  C CE2 . TYR A 1 329 ? 117.607 141.327 149.843 1.00 13.56  ? 294 TYR A CE2 1 
ATOM   2276  C CZ  . TYR A 1 329 ? 118.208 142.037 150.859 1.00 15.56  ? 294 TYR A CZ  1 
ATOM   2277  O OH  . TYR A 1 329 ? 119.512 141.766 151.201 1.00 19.70  ? 294 TYR A OH  1 
ATOM   2278  N N   . ALA A 1 330 ? 111.841 144.207 151.520 1.00 11.80  ? 295 ALA A N   1 
ATOM   2279  C CA  . ALA A 1 330 ? 111.415 145.179 152.521 1.00 10.67  ? 295 ALA A CA  1 
ATOM   2280  C C   . ALA A 1 330 ? 110.689 144.491 153.669 1.00 11.15  ? 295 ALA A C   1 
ATOM   2281  O O   . ALA A 1 330 ? 110.877 144.852 154.837 1.00 12.15  ? 295 ALA A O   1 
ATOM   2282  C CB  . ALA A 1 330 ? 110.526 146.243 151.880 1.00 8.93   ? 295 ALA A CB  1 
ATOM   2283  N N   . PHE A 1 331 ? 109.841 143.508 153.355 1.00 10.52  ? 296 PHE A N   1 
ATOM   2284  C CA  . PHE A 1 331 ? 109.125 142.784 154.401 1.00 10.17  ? 296 PHE A CA  1 
ATOM   2285  C C   . PHE A 1 331 ? 110.102 142.045 155.302 1.00 10.95  ? 296 PHE A C   1 
ATOM   2286  O O   . PHE A 1 331 ? 110.018 142.125 156.533 1.00 13.54  ? 296 PHE A O   1 
ATOM   2287  C CB  . PHE A 1 331 ? 108.121 141.810 153.785 1.00 10.61  ? 296 PHE A CB  1 
ATOM   2288  C CG  . PHE A 1 331 ? 106.765 142.404 153.553 1.00 13.36  ? 296 PHE A CG  1 
ATOM   2289  C CD1 . PHE A 1 331 ? 105.817 142.409 154.560 1.00 15.90  ? 296 PHE A CD1 1 
ATOM   2290  C CD2 . PHE A 1 331 ? 106.431 142.945 152.324 1.00 13.76  ? 296 PHE A CD2 1 
ATOM   2291  C CE1 . PHE A 1 331 ? 104.568 142.952 154.350 1.00 18.44  ? 296 PHE A CE1 1 
ATOM   2292  C CE2 . PHE A 1 331 ? 105.183 143.489 152.108 1.00 17.11  ? 296 PHE A CE2 1 
ATOM   2293  C CZ  . PHE A 1 331 ? 104.251 143.493 153.121 1.00 20.64  ? 296 PHE A CZ  1 
ATOM   2294  N N   . VAL A 1 332 ? 111.033 141.304 154.698 1.00 11.08  ? 297 VAL A N   1 
ATOM   2295  C CA  . VAL A 1 332 ? 112.023 140.567 155.476 1.00 11.53  ? 297 VAL A CA  1 
ATOM   2296  C C   . VAL A 1 332 ? 112.917 141.535 156.240 1.00 13.67  ? 297 VAL A C   1 
ATOM   2297  O O   . VAL A 1 332 ? 113.338 141.259 157.370 1.00 15.28  ? 297 VAL A O   1 
ATOM   2298  C CB  . VAL A 1 332 ? 112.833 139.640 154.550 1.00 8.64   ? 297 VAL A CB  1 
ATOM   2299  C CG1 . VAL A 1 332 ? 113.985 139.008 155.297 1.00 9.35   ? 297 VAL A CG1 1 
ATOM   2300  C CG2 . VAL A 1 332 ? 111.934 138.573 153.955 1.00 10.72  ? 297 VAL A CG2 1 
ATOM   2301  N N   . PHE A 1 333 ? 113.213 142.691 155.640 1.00 11.59  ? 298 PHE A N   1 
ATOM   2302  C CA  . PHE A 1 333 ? 113.966 143.719 156.349 1.00 9.49   ? 298 PHE A CA  1 
ATOM   2303  C C   . PHE A 1 333 ? 113.175 144.247 157.538 1.00 10.99  ? 298 PHE A C   1 
ATOM   2304  O O   . PHE A 1 333 ? 113.727 144.440 158.626 1.00 13.88  ? 298 PHE A O   1 
ATOM   2305  C CB  . PHE A 1 333 ? 114.330 144.852 155.385 1.00 12.31  ? 298 PHE A CB  1 
ATOM   2306  C CG  . PHE A 1 333 ? 114.700 146.146 156.058 1.00 13.45  ? 298 PHE A CG  1 
ATOM   2307  C CD1 . PHE A 1 333 ? 116.007 146.396 156.429 1.00 10.62  ? 298 PHE A CD1 1 
ATOM   2308  C CD2 . PHE A 1 333 ? 113.749 147.128 156.282 1.00 13.99  ? 298 PHE A CD2 1 
ATOM   2309  C CE1 . PHE A 1 333 ? 116.354 147.586 157.038 1.00 9.94   ? 298 PHE A CE1 1 
ATOM   2310  C CE2 . PHE A 1 333 ? 114.092 148.319 156.891 1.00 12.40  ? 298 PHE A CE2 1 
ATOM   2311  C CZ  . PHE A 1 333 ? 115.397 148.548 157.268 1.00 11.06  ? 298 PHE A CZ  1 
ATOM   2312  N N   . SER A 1 334 ? 111.873 144.478 157.350 1.00 11.07  ? 299 SER A N   1 
ATOM   2313  C CA  . SER A 1 334 ? 111.048 145.028 158.418 1.00 12.99  ? 299 SER A CA  1 
ATOM   2314  C C   . SER A 1 334 ? 110.798 144.022 159.531 1.00 16.06  ? 299 SER A C   1 
ATOM   2315  O O   . SER A 1 334 ? 110.494 144.427 160.658 1.00 20.11  ? 299 SER A O   1 
ATOM   2316  C CB  . SER A 1 334 ? 109.716 145.524 157.857 1.00 11.43  ? 299 SER A CB  1 
ATOM   2317  O OG  . SER A 1 334 ? 109.917 146.546 156.898 1.00 10.27  ? 299 SER A OG  1 
ATOM   2318  N N   . ALA A 1 335 ? 110.903 142.724 159.243 1.00 14.53  ? 300 ALA A N   1 
ATOM   2319  C CA  . ALA A 1 335 ? 110.695 141.726 160.285 1.00 16.16  ? 300 ALA A CA  1 
ATOM   2320  C C   . ALA A 1 335 ? 111.848 141.729 161.278 1.00 18.14  ? 300 ALA A C   1 
ATOM   2321  O O   . ALA A 1 335 ? 111.643 141.525 162.480 1.00 24.30  ? 300 ALA A O   1 
ATOM   2322  C CB  . ALA A 1 335 ? 110.519 140.341 159.665 1.00 15.55  ? 300 ALA A CB  1 
ATOM   2323  N N   . LEU A 1 336 ? 113.070 141.954 160.793 1.00 13.71  ? 301 LEU A N   1 
ATOM   2324  C CA  . LEU A 1 336 ? 114.220 142.044 161.683 1.00 14.47  ? 301 LEU A CA  1 
ATOM   2325  C C   . LEU A 1 336 ? 114.277 143.387 162.398 1.00 18.83  ? 301 LEU A C   1 
ATOM   2326  O O   . LEU A 1 336 ? 114.734 143.456 163.544 1.00 22.10  ? 301 LEU A O   1 
ATOM   2327  C CB  . LEU A 1 336 ? 115.505 141.806 160.892 1.00 10.90  ? 301 LEU A CB  1 
ATOM   2328  C CG  . LEU A 1 336 ? 116.818 141.844 161.668 1.00 9.72   ? 301 LEU A CG  1 
ATOM   2329  C CD1 . LEU A 1 336 ? 116.777 140.875 162.836 1.00 10.77  ? 301 LEU A CD1 1 
ATOM   2330  C CD2 . LEU A 1 336 ? 117.965 141.518 160.741 1.00 9.61   ? 301 LEU A CD2 1 
ATOM   2331  N N   . ILE A 1 337 ? 113.823 144.458 161.743 1.00 17.80  ? 302 ILE A N   1 
ATOM   2332  C CA  . ILE A 1 337 ? 113.682 145.741 162.423 1.00 17.80  ? 302 ILE A CA  1 
ATOM   2333  C C   . ILE A 1 337 ? 112.616 145.653 163.505 1.00 21.43  ? 302 ILE A C   1 
ATOM   2334  O O   . ILE A 1 337 ? 112.732 146.295 164.556 1.00 23.22  ? 302 ILE A O   1 
ATOM   2335  C CB  . ILE A 1 337 ? 113.365 146.851 161.403 1.00 15.36  ? 302 ILE A CB  1 
ATOM   2336  C CG1 . ILE A 1 337 ? 114.515 147.005 160.408 1.00 15.20  ? 302 ILE A CG1 1 
ATOM   2337  C CG2 . ILE A 1 337 ? 113.089 148.173 162.103 1.00 17.18  ? 302 ILE A CG2 1 
ATOM   2338  C CD1 . ILE A 1 337 ? 115.774 147.581 161.018 1.00 16.15  ? 302 ILE A CD1 1 
ATOM   2339  N N   . GLU A 1 338 ? 111.565 144.864 163.272 1.00 23.57  ? 303 GLU A N   1 
ATOM   2340  C CA  . GLU A 1 338 ? 110.516 144.715 164.273 1.00 23.91  ? 303 GLU A CA  1 
ATOM   2341  C C   . GLU A 1 338 ? 111.065 144.089 165.548 1.00 28.15  ? 303 GLU A C   1 
ATOM   2342  O O   . GLU A 1 338 ? 110.707 144.506 166.656 1.00 34.99  ? 303 GLU A O   1 
ATOM   2343  C CB  . GLU A 1 338 ? 109.363 143.887 163.703 1.00 23.31  ? 303 GLU A CB  1 
ATOM   2344  C CG  . GLU A 1 338 ? 108.169 143.732 164.633 1.00 29.50  ? 303 GLU A CG  1 
ATOM   2345  C CD  . GLU A 1 338 ? 108.188 142.445 165.433 1.00 33.02  ? 303 GLU A CD  1 
ATOM   2346  O OE1 . GLU A 1 338 ? 109.259 141.814 165.544 1.00 32.78  ? 303 GLU A OE1 1 
ATOM   2347  O OE2 . GLU A 1 338 ? 107.120 142.063 165.952 1.00 37.48  ? 303 GLU A OE2 1 
ATOM   2348  N N   . PHE A 1 339 ? 111.933 143.083 165.415 1.00 26.40  ? 304 PHE A N   1 
ATOM   2349  C CA  . PHE A 1 339 ? 112.508 142.461 166.602 1.00 30.28  ? 304 PHE A CA  1 
ATOM   2350  C C   . PHE A 1 339 ? 113.490 143.394 167.294 1.00 34.76  ? 304 PHE A C   1 
ATOM   2351  O O   . PHE A 1 339 ? 113.640 143.336 168.520 1.00 35.04  ? 304 PHE A O   1 
ATOM   2352  C CB  . PHE A 1 339 ? 113.198 141.149 166.237 1.00 22.59  ? 304 PHE A CB  1 
ATOM   2353  C CG  . PHE A 1 339 ? 113.838 140.461 167.407 1.00 25.69  ? 304 PHE A CG  1 
ATOM   2354  C CD1 . PHE A 1 339 ? 113.066 139.975 168.448 1.00 30.19  ? 304 PHE A CD1 1 
ATOM   2355  C CD2 . PHE A 1 339 ? 115.212 140.311 167.471 1.00 25.35  ? 304 PHE A CD2 1 
ATOM   2356  C CE1 . PHE A 1 339 ? 113.650 139.345 169.525 1.00 29.71  ? 304 PHE A CE1 1 
ATOM   2357  C CE2 . PHE A 1 339 ? 115.801 139.685 168.547 1.00 28.70  ? 304 PHE A CE2 1 
ATOM   2358  C CZ  . PHE A 1 339 ? 115.019 139.201 169.575 1.00 31.15  ? 304 PHE A CZ  1 
ATOM   2359  N N   . ALA A 1 340 ? 114.174 144.247 166.527 1.00 30.49  ? 305 ALA A N   1 
ATOM   2360  C CA  . ALA A 1 340 ? 115.034 145.260 167.128 1.00 29.09  ? 305 ALA A CA  1 
ATOM   2361  C C   . ALA A 1 340 ? 114.242 146.151 168.074 1.00 33.57  ? 305 ALA A C   1 
ATOM   2362  O O   . ALA A 1 340 ? 114.753 146.579 169.115 1.00 33.60  ? 305 ALA A O   1 
ATOM   2363  C CB  . ALA A 1 340 ? 115.706 146.092 166.037 1.00 26.11  ? 305 ALA A CB  1 
ATOM   2364  N N   . THR A 1 341 ? 112.990 146.449 167.720 1.00 34.04  ? 306 THR A N   1 
ATOM   2365  C CA  . THR A 1 341 ? 112.131 147.231 168.600 1.00 34.34  ? 306 THR A CA  1 
ATOM   2366  C C   . THR A 1 341 ? 111.639 146.398 169.777 1.00 37.68  ? 306 THR A C   1 
ATOM   2367  O O   . THR A 1 341 ? 111.613 146.880 170.915 1.00 45.00  ? 306 THR A O   1 
ATOM   2368  C CB  . THR A 1 341 ? 110.949 147.796 167.815 1.00 34.51  ? 306 THR A CB  1 
ATOM   2369  O OG1 . THR A 1 341 ? 111.429 148.462 166.641 1.00 29.41  ? 306 THR A OG1 1 
ATOM   2370  C CG2 . THR A 1 341 ? 110.174 148.787 168.665 1.00 39.15  ? 306 THR A CG2 1 
ATOM   2371  N N   . VAL A 1 342 ? 111.240 145.149 169.524 1.00 33.93  ? 307 VAL A N   1 
ATOM   2372  C CA  . VAL A 1 342 ? 110.765 144.288 170.606 1.00 38.04  ? 307 VAL A CA  1 
ATOM   2373  C C   . VAL A 1 342 ? 111.861 144.085 171.643 1.00 39.71  ? 307 VAL A C   1 
ATOM   2374  O O   . VAL A 1 342 ? 111.631 144.214 172.851 1.00 43.28  ? 307 VAL A O   1 
ATOM   2375  C CB  . VAL A 1 342 ? 110.266 142.944 170.045 1.00 37.18  ? 307 VAL A CB  1 
ATOM   2376  C CG1 . VAL A 1 342 ? 109.919 141.993 171.177 1.00 44.31  ? 307 VAL A CG1 1 
ATOM   2377  C CG2 . VAL A 1 342 ? 109.067 143.158 169.140 1.00 36.64  ? 307 VAL A CG2 1 
ATOM   2378  N N   . ASN A 1 343 ? 113.071 143.756 171.185 1.00 39.48  ? 308 ASN A N   1 
ATOM   2379  C CA  . ASN A 1 343 ? 114.175 143.531 172.112 1.00 43.17  ? 308 ASN A CA  1 
ATOM   2380  C C   . ASN A 1 343 ? 114.532 144.799 172.877 1.00 41.73  ? 308 ASN A C   1 
ATOM   2381  O O   . ASN A 1 343 ? 115.075 144.722 173.985 1.00 42.34  ? 308 ASN A O   1 
ATOM   2382  C CB  . ASN A 1 343 ? 115.395 143.001 171.360 1.00 40.73  ? 308 ASN A CB  1 
ATOM   2383  C CG  . ASN A 1 343 ? 116.600 142.824 172.258 1.00 35.95  ? 308 ASN A CG  1 
ATOM   2384  O OD1 . ASN A 1 343 ? 117.490 143.671 172.296 1.00 32.15  ? 308 ASN A OD1 1 
ATOM   2385  N ND2 . ASN A 1 343 ? 116.633 141.719 172.992 1.00 35.92  ? 308 ASN A ND2 1 
ATOM   2386  N N   . TYR A 1 344 ? 114.240 145.971 172.309 1.00 41.49  ? 309 TYR A N   1 
ATOM   2387  C CA  . TYR A 1 344 ? 114.577 147.220 172.977 1.00 42.78  ? 309 TYR A CA  1 
ATOM   2388  C C   . TYR A 1 344 ? 113.699 147.493 174.191 1.00 46.50  ? 309 TYR A C   1 
ATOM   2389  O O   . TYR A 1 344 ? 114.037 148.370 174.992 1.00 48.69  ? 309 TYR A O   1 
ATOM   2390  C CB  . TYR A 1 344 ? 114.473 148.379 171.982 1.00 41.20  ? 309 TYR A CB  1 
ATOM   2391  C CG  . TYR A 1 344 ? 115.064 149.682 172.472 1.00 42.70  ? 309 TYR A CG  1 
ATOM   2392  C CD1 . TYR A 1 344 ? 116.434 149.900 172.443 1.00 43.19  ? 309 TYR A CD1 1 
ATOM   2393  C CD2 . TYR A 1 344 ? 114.250 150.700 172.949 1.00 43.16  ? 309 TYR A CD2 1 
ATOM   2394  C CE1 . TYR A 1 344 ? 116.977 151.090 172.887 1.00 45.05  ? 309 TYR A CE1 1 
ATOM   2395  C CE2 . TYR A 1 344 ? 114.783 151.892 173.393 1.00 45.83  ? 309 TYR A CE2 1 
ATOM   2396  C CZ  . TYR A 1 344 ? 116.146 152.082 173.360 1.00 49.05  ? 309 TYR A CZ  1 
ATOM   2397  O OH  . TYR A 1 344 ? 116.681 153.271 173.802 1.00 49.69  ? 309 TYR A OH  1 
ATOM   2398  N N   . PHE A 1 345 ? 112.594 146.765 174.352 1.00 45.11  ? 310 PHE A N   1 
ATOM   2399  C CA  . PHE A 1 345 ? 111.707 146.945 175.490 1.00 45.41  ? 310 PHE A CA  1 
ATOM   2400  C C   . PHE A 1 345 ? 111.616 145.708 176.371 1.00 51.63  ? 310 PHE A C   1 
ATOM   2401  O O   . PHE A 1 345 ? 110.823 145.700 177.320 1.00 57.19  ? 310 PHE A O   1 
ATOM   2402  C CB  . PHE A 1 345 ? 110.303 147.350 175.020 1.00 46.21  ? 310 PHE A CB  1 
ATOM   2403  C CG  . PHE A 1 345 ? 110.264 148.666 174.299 1.00 47.04  ? 310 PHE A CG  1 
ATOM   2404  C CD1 . PHE A 1 345 ? 110.250 149.856 175.005 1.00 48.61  ? 310 PHE A CD1 1 
ATOM   2405  C CD2 . PHE A 1 345 ? 110.242 148.714 172.918 1.00 48.32  ? 310 PHE A CD2 1 
ATOM   2406  C CE1 . PHE A 1 345 ? 110.214 151.067 174.345 1.00 47.39  ? 310 PHE A CE1 1 
ATOM   2407  C CE2 . PHE A 1 345 ? 110.207 149.922 172.252 1.00 48.96  ? 310 PHE A CE2 1 
ATOM   2408  C CZ  . PHE A 1 345 ? 110.193 151.100 172.967 1.00 49.79  ? 310 PHE A CZ  1 
ATOM   2409  N N   . THR A 1 346 ? 112.392 144.666 176.088 1.00 51.98  ? 311 THR A N   1 
ATOM   2410  C CA  . THR A 1 346 ? 112.457 143.520 176.983 1.00 55.56  ? 311 THR A CA  1 
ATOM   2411  C C   . THR A 1 346 ? 113.241 143.881 178.236 1.00 64.13  ? 311 THR A C   1 
ATOM   2412  O O   . THR A 1 346 ? 114.342 144.435 178.154 1.00 65.18  ? 311 THR A O   1 
ATOM   2413  C CB  . THR A 1 346 ? 113.112 142.334 176.278 1.00 55.38  ? 311 THR A CB  1 
ATOM   2414  O OG1 . THR A 1 346 ? 112.493 142.130 175.001 1.00 51.17  ? 311 THR A OG1 1 
ATOM   2415  C CG2 . THR A 1 346 ? 112.972 141.072 177.112 1.00 65.96  ? 311 THR A CG2 1 
ATOM   2416  N N   . LYS A 1 347 ? 112.675 143.567 179.399 1.00 77.31  ? 312 LYS A N   1 
ATOM   2417  C CA  . LYS A 1 347 ? 113.285 143.932 180.671 1.00 83.64  ? 312 LYS A CA  1 
ATOM   2418  C C   . LYS A 1 347 ? 114.045 142.784 181.320 1.00 86.03  ? 312 LYS A C   1 
ATOM   2419  O O   . LYS A 1 347 ? 115.087 143.012 181.942 1.00 85.05  ? 312 LYS A O   1 
ATOM   2420  C CB  . LYS A 1 347 ? 112.220 144.448 181.645 1.00 83.60  ? 312 LYS A CB  1 
ATOM   2421  C CG  . LYS A 1 347 ? 111.568 145.753 181.219 1.00 78.43  ? 312 LYS A CG  1 
ATOM   2422  C CD  . LYS A 1 347 ? 110.577 146.238 182.262 1.00 76.89  ? 312 LYS A CD  1 
ATOM   2423  C CE  . LYS A 1 347 ? 109.876 147.509 181.811 1.00 77.78  ? 312 LYS A CE  1 
ATOM   2424  N NZ  . LYS A 1 347 ? 108.845 147.949 182.792 1.00 81.37  ? 312 LYS A NZ  1 
ATOM   2425  N N   . ARG A 1 348 ? 113.555 141.556 181.183 1.00 87.62  ? 313 ARG A N   1 
ATOM   2426  C CA  . ARG A 1 348 ? 114.132 140.396 181.846 1.00 94.54  ? 313 ARG A CA  1 
ATOM   2427  C C   . ARG A 1 348 ? 114.733 139.449 180.816 1.00 98.85  ? 313 ARG A C   1 
ATOM   2428  O O   . ARG A 1 348 ? 114.109 139.163 179.789 1.00 97.64  ? 313 ARG A O   1 
ATOM   2429  C CB  . ARG A 1 348 ? 113.078 139.670 182.684 1.00 99.66  ? 313 ARG A CB  1 
ATOM   2430  C CG  . ARG A 1 348 ? 112.421 140.550 183.737 1.00 98.76  ? 313 ARG A CG  1 
ATOM   2431  C CD  . ARG A 1 348 ? 111.061 140.008 184.148 1.00 100.10 ? 313 ARG A CD  1 
ATOM   2432  N NE  . ARG A 1 348 ? 110.344 140.935 185.015 1.00 100.96 ? 313 ARG A NE  1 
ATOM   2433  C CZ  . ARG A 1 348 ? 109.667 141.992 184.588 1.00 103.66 ? 313 ARG A CZ  1 
ATOM   2434  N NH1 . ARG A 1 348 ? 109.607 142.303 183.303 1.00 102.40 ? 313 ARG A NH1 1 
ATOM   2435  N NH2 . ARG A 1 348 ? 109.040 142.762 185.473 1.00 100.64 ? 313 ARG A NH2 1 
ATOM   2436  N N   . GLY A 1 349 ? 115.942 138.968 181.099 1.00 103.10 ? 314 GLY A N   1 
ATOM   2437  C CA  . GLY A 1 349 ? 116.646 138.047 180.226 1.00 111.22 ? 314 GLY A CA  1 
ATOM   2438  C C   . GLY A 1 349 ? 116.205 136.602 180.313 1.00 114.94 ? 314 GLY A C   1 
ATOM   2439  O O   . GLY A 1 349 ? 116.666 135.782 179.514 1.00 119.30 ? 314 GLY A O   1 
ATOM   2440  N N   . TYR A 1 350 ? 115.328 136.271 181.256 1.00 109.41 ? 315 TYR A N   1 
ATOM   2441  C CA  . TYR A 1 350 ? 114.843 134.913 181.443 1.00 102.35 ? 315 TYR A CA  1 
ATOM   2442  C C   . TYR A 1 350 ? 113.405 134.781 180.956 1.00 97.50  ? 315 TYR A C   1 
ATOM   2443  O O   . TYR A 1 350 ? 112.615 135.726 181.029 1.00 99.14  ? 315 TYR A O   1 
ATOM   2444  C CB  . TYR A 1 350 ? 114.941 134.501 182.917 1.00 106.17 ? 315 TYR A CB  1 
ATOM   2445  C CG  . TYR A 1 350 ? 114.203 135.417 183.870 1.00 108.45 ? 315 TYR A CG  1 
ATOM   2446  C CD1 . TYR A 1 350 ? 112.856 135.227 184.151 1.00 104.26 ? 315 TYR A CD1 1 
ATOM   2447  C CD2 . TYR A 1 350 ? 114.857 136.472 184.494 1.00 106.51 ? 315 TYR A CD2 1 
ATOM   2448  C CE1 . TYR A 1 350 ? 112.182 136.064 185.020 1.00 105.08 ? 315 TYR A CE1 1 
ATOM   2449  C CE2 . TYR A 1 350 ? 114.191 137.313 185.365 1.00 101.64 ? 315 TYR A CE2 1 
ATOM   2450  C CZ  . TYR A 1 350 ? 112.854 137.104 185.624 1.00 105.69 ? 315 TYR A CZ  1 
ATOM   2451  O OH  . TYR A 1 350 ? 112.187 137.937 186.492 1.00 106.87 ? 315 TYR A OH  1 
ATOM   2452  N N   . ALA A 1 351 ? 113.078 133.590 180.462 1.00 91.07  ? 316 ALA A N   1 
ATOM   2453  C CA  . ALA A 1 351 ? 111.752 133.284 179.950 1.00 92.56  ? 316 ALA A CA  1 
ATOM   2454  C C   . ALA A 1 351 ? 110.866 132.667 181.033 1.00 106.55 ? 316 ALA A C   1 
ATOM   2455  O O   . ALA A 1 351 ? 111.313 132.337 182.133 1.00 115.17 ? 316 ALA A O   1 
ATOM   2456  C CB  . ALA A 1 351 ? 111.848 132.347 178.746 1.00 80.78  ? 316 ALA A CB  1 
ATOM   2457  N N   . TRP A 1 352 ? 109.584 132.529 180.699 1.00 101.31 ? 317 TRP A N   1 
ATOM   2458  C CA  . TRP A 1 352 ? 108.618 131.889 181.584 1.00 107.14 ? 317 TRP A CA  1 
ATOM   2459  C C   . TRP A 1 352 ? 109.028 130.456 181.907 1.00 103.42 ? 317 TRP A C   1 
ATOM   2460  O O   . TRP A 1 352 ? 109.392 129.683 181.016 1.00 96.18  ? 317 TRP A O   1 
ATOM   2461  C CB  . TRP A 1 352 ? 107.233 131.918 180.938 1.00 107.52 ? 317 TRP A CB  1 
ATOM   2462  C CG  . TRP A 1 352 ? 106.154 131.281 181.758 1.00 105.70 ? 317 TRP A CG  1 
ATOM   2463  C CD1 . TRP A 1 352 ? 105.719 131.676 182.988 1.00 102.04 ? 317 TRP A CD1 1 
ATOM   2464  C CD2 . TRP A 1 352 ? 105.350 130.154 181.390 1.00 102.98 ? 317 TRP A CD2 1 
ATOM   2465  N NE1 . TRP A 1 352 ? 104.704 130.855 183.417 1.00 101.49 ? 317 TRP A NE1 1 
ATOM   2466  C CE2 . TRP A 1 352 ? 104.458 129.913 182.453 1.00 101.90 ? 317 TRP A CE2 1 
ATOM   2467  C CE3 . TRP A 1 352 ? 105.302 129.321 180.269 1.00 97.86  ? 317 TRP A CE3 1 
ATOM   2468  C CZ2 . TRP A 1 352 ? 103.530 128.875 182.428 1.00 100.45 ? 317 TRP A CZ2 1 
ATOM   2469  C CZ3 . TRP A 1 352 ? 104.380 128.291 180.246 1.00 99.46  ? 317 TRP A CZ3 1 
ATOM   2470  C CH2 . TRP A 1 352 ? 103.506 128.078 181.318 1.00 99.79  ? 317 TRP A CH2 1 
ATOM   2471  N N   . ASP A 1 353 ? 108.968 130.106 183.193 1.00 103.07 ? 318 ASP A N   1 
ATOM   2472  C CA  . ASP A 1 353 ? 109.525 128.857 183.696 1.00 100.66 ? 318 ASP A CA  1 
ATOM   2473  C C   . ASP A 1 353 ? 108.588 127.669 183.521 1.00 101.26 ? 318 ASP A C   1 
ATOM   2474  O O   . ASP A 1 353 ? 108.985 126.540 183.827 1.00 97.97  ? 318 ASP A O   1 
ATOM   2475  C CB  . ASP A 1 353 ? 109.899 128.995 185.177 1.00 111.45 ? 318 ASP A CB  1 
ATOM   2476  C CG  . ASP A 1 353 ? 108.744 129.492 186.034 1.00 115.13 ? 318 ASP A CG  1 
ATOM   2477  O OD1 . ASP A 1 353 ? 107.600 129.555 185.535 1.00 112.52 ? 318 ASP A OD1 1 
ATOM   2478  O OD2 . ASP A 1 353 ? 108.983 129.819 187.215 1.00 116.19 ? 318 ASP A OD2 1 
ATOM   2479  N N   . GLY A 1 354 ? 107.365 127.890 183.043 1.00 104.36 ? 319 GLY A N   1 
ATOM   2480  C CA  . GLY A 1 354 ? 106.428 126.816 182.804 1.00 101.70 ? 319 GLY A CA  1 
ATOM   2481  C C   . GLY A 1 354 ? 105.516 126.473 183.964 1.00 99.82  ? 319 GLY A C   1 
ATOM   2482  O O   . GLY A 1 354 ? 104.609 125.649 183.790 1.00 93.87  ? 319 GLY A O   1 
ATOM   2483  N N   . LYS A 1 355 ? 105.718 127.072 185.135 1.00 105.99 ? 320 LYS A N   1 
ATOM   2484  C CA  . LYS A 1 355 ? 104.950 126.721 186.328 1.00 105.23 ? 320 LYS A CA  1 
ATOM   2485  C C   . LYS A 1 355 ? 104.550 127.985 187.085 1.00 108.95 ? 320 LYS A C   1 
ATOM   2486  O O   . LYS A 1 355 ? 104.660 128.073 188.309 1.00 110.80 ? 320 LYS A O   1 
ATOM   2487  C CB  . LYS A 1 355 ? 105.735 125.767 187.227 1.00 106.04 ? 320 LYS A CB  1 
ATOM   2488  C CG  . LYS A 1 355 ? 107.114 126.267 187.632 1.00 114.23 ? 320 LYS A CG  1 
ATOM   2489  C CD  . LYS A 1 355 ? 107.813 125.267 188.538 1.00 120.27 ? 320 LYS A CD  1 
ATOM   2490  C CE  . LYS A 1 355 ? 109.171 125.780 188.986 1.00 111.93 ? 320 LYS A CE  1 
ATOM   2491  N NZ  . LYS A 1 355 ? 109.871 124.798 189.858 1.00 98.17  ? 320 LYS A NZ  1 
ATOM   2492  N N   . SER A 1 356 ? 104.063 128.981 186.352 1.00 110.01 ? 321 SER A N   1 
ATOM   2493  C CA  . SER A 1 356 ? 103.625 130.236 186.955 1.00 109.80 ? 321 SER A CA  1 
ATOM   2494  C C   . SER A 1 356 ? 102.541 130.896 186.109 1.00 101.43 ? 321 SER A C   1 
ATOM   2495  O O   . SER A 1 356 ? 101.681 131.607 186.628 1.00 96.45  ? 321 SER A O   1 
ATOM   2496  C CB  . SER A 1 356 ? 104.806 131.193 187.138 1.00 111.75 ? 321 SER A CB  1 
ATOM   2497  O OG  . SER A 1 356 ? 105.849 130.590 187.884 1.00 110.42 ? 321 SER A OG  1 
ATOM   2498  N N   . LYS A 1 419 ? 108.334 135.758 191.606 1.00 110.96 ? 384 LYS A N   1 
ATOM   2499  C CA  . LYS A 1 419 ? 109.084 135.891 190.363 1.00 109.42 ? 384 LYS A CA  1 
ATOM   2500  C C   . LYS A 1 419 ? 108.165 136.247 189.201 1.00 111.17 ? 384 LYS A C   1 
ATOM   2501  O O   . LYS A 1 419 ? 107.250 135.493 188.871 1.00 115.34 ? 384 LYS A O   1 
ATOM   2502  C CB  . LYS A 1 419 ? 109.832 134.592 190.057 1.00 104.56 ? 384 LYS A CB  1 
ATOM   2503  C CG  . LYS A 1 419 ? 110.693 134.638 188.807 1.00 102.84 ? 384 LYS A CG  1 
ATOM   2504  C CD  . LYS A 1 419 ? 111.527 133.372 188.679 1.00 104.00 ? 384 LYS A CD  1 
ATOM   2505  C CE  . LYS A 1 419 ? 112.420 133.413 187.451 1.00 101.94 ? 384 LYS A CE  1 
ATOM   2506  N NZ  . LYS A 1 419 ? 113.306 132.217 187.377 1.00 87.21  ? 384 LYS A NZ  1 
ATOM   2507  N N   . THR A 1 420 ? 108.411 137.397 188.583 1.00 110.00 ? 385 THR A N   1 
ATOM   2508  C CA  . THR A 1 420 ? 107.607 137.859 187.463 1.00 109.65 ? 385 THR A CA  1 
ATOM   2509  C C   . THR A 1 420 ? 108.326 137.601 186.143 1.00 105.15 ? 385 THR A C   1 
ATOM   2510  O O   . THR A 1 420 ? 109.547 137.439 186.091 1.00 104.47 ? 385 THR A O   1 
ATOM   2511  C CB  . THR A 1 420 ? 107.286 139.350 187.599 1.00 111.33 ? 385 THR A CB  1 
ATOM   2512  O OG1 . THR A 1 420 ? 108.487 140.075 187.895 1.00 111.78 ? 385 THR A OG1 1 
ATOM   2513  C CG2 . THR A 1 420 ? 106.275 139.576 188.712 1.00 106.36 ? 385 THR A CG2 1 
ATOM   2514  N N   . PHE A 1 421 ? 107.542 137.570 185.069 1.00 103.72 ? 386 PHE A N   1 
ATOM   2515  C CA  . PHE A 1 421 ? 108.039 137.277 183.735 1.00 106.80 ? 386 PHE A CA  1 
ATOM   2516  C C   . PHE A 1 421 ? 107.567 138.352 182.768 1.00 103.74 ? 386 PHE A C   1 
ATOM   2517  O O   . PHE A 1 421 ? 106.558 139.024 182.998 1.00 103.34 ? 386 PHE A O   1 
ATOM   2518  C CB  . PHE A 1 421 ? 107.592 135.892 183.256 1.00 105.71 ? 386 PHE A CB  1 
ATOM   2519  C CG  . PHE A 1 421 ? 108.074 134.774 184.129 1.00 107.08 ? 386 PHE A CG  1 
ATOM   2520  C CD1 . PHE A 1 421 ? 109.382 134.332 184.043 1.00 106.74 ? 386 PHE A CD1 1 
ATOM   2521  C CD2 . PHE A 1 421 ? 107.225 134.171 185.038 1.00 107.93 ? 386 PHE A CD2 1 
ATOM   2522  C CE1 . PHE A 1 421 ? 109.834 133.307 184.846 1.00 107.62 ? 386 PHE A CE1 1 
ATOM   2523  C CE2 . PHE A 1 421 ? 107.672 133.144 185.844 1.00 109.16 ? 386 PHE A CE2 1 
ATOM   2524  C CZ  . PHE A 1 421 ? 108.978 132.714 185.747 1.00 109.47 ? 386 PHE A CZ  1 
ATOM   2525  N N   . ASN A 1 422 ? 108.316 138.514 181.680 1.00 97.03  ? 387 ASN A N   1 
ATOM   2526  C CA  . ASN A 1 422 ? 107.909 139.452 180.645 1.00 89.67  ? 387 ASN A CA  1 
ATOM   2527  C C   . ASN A 1 422 ? 106.608 138.986 180.005 1.00 91.02  ? 387 ASN A C   1 
ATOM   2528  O O   . ASN A 1 422 ? 106.400 137.792 179.774 1.00 89.14  ? 387 ASN A O   1 
ATOM   2529  C CB  . ASN A 1 422 ? 109.005 139.585 179.589 1.00 83.91  ? 387 ASN A CB  1 
ATOM   2530  C CG  . ASN A 1 422 ? 110.321 140.058 180.172 1.00 88.83  ? 387 ASN A CG  1 
ATOM   2531  O OD1 . ASN A 1 422 ? 110.347 140.852 181.112 1.00 89.64  ? 387 ASN A OD1 1 
ATOM   2532  N ND2 . ASN A 1 422 ? 111.423 139.564 179.622 1.00 85.71  ? 387 ASN A ND2 1 
ATOM   2533  N N   . SER A 1 423 ? 105.730 139.942 179.721 1.00 90.12  ? 388 SER A N   1 
ATOM   2534  C CA  . SER A 1 423 ? 104.531 139.679 178.945 1.00 83.69  ? 388 SER A CA  1 
ATOM   2535  C C   . SER A 1 423 ? 104.855 139.578 177.459 1.00 76.33  ? 388 SER A C   1 
ATOM   2536  O O   . SER A 1 423 ? 105.902 140.031 176.988 1.00 70.73  ? 388 SER A O   1 
ATOM   2537  C CB  . SER A 1 423 ? 103.491 140.775 179.177 1.00 79.50  ? 388 SER A CB  1 
ATOM   2538  O OG  . SER A 1 423 ? 104.025 142.052 178.875 1.00 79.80  ? 388 SER A OG  1 
ATOM   2539  N N   . VAL A 1 424 ? 103.933 138.966 176.716 1.00 73.93  ? 389 VAL A N   1 
ATOM   2540  C CA  . VAL A 1 424 ? 104.074 138.894 175.270 1.00 65.94  ? 389 VAL A CA  1 
ATOM   2541  C C   . VAL A 1 424 ? 103.897 140.291 174.696 1.00 60.44  ? 389 VAL A C   1 
ATOM   2542  O O   . VAL A 1 424 ? 102.927 140.991 175.012 1.00 58.56  ? 389 VAL A O   1 
ATOM   2543  C CB  . VAL A 1 424 ? 103.056 137.911 174.673 1.00 61.32  ? 389 VAL A CB  1 
ATOM   2544  C CG1 . VAL A 1 424 ? 103.248 137.797 173.169 1.00 58.55  ? 389 VAL A CG1 1 
ATOM   2545  C CG2 . VAL A 1 424 ? 103.183 136.548 175.336 1.00 57.68  ? 389 VAL A CG2 1 
ATOM   2546  N N   . SER A 1 425 ? 104.842 140.702 173.855 1.00 60.28  ? 390 SER A N   1 
ATOM   2547  C CA  . SER A 1 425 ? 104.863 142.067 173.349 1.00 60.10  ? 390 SER A CA  1 
ATOM   2548  C C   . SER A 1 425 ? 103.584 142.392 172.589 1.00 57.04  ? 390 SER A C   1 
ATOM   2549  O O   . SER A 1 425 ? 103.059 141.566 171.838 1.00 54.88  ? 390 SER A O   1 
ATOM   2550  C CB  . SER A 1 425 ? 106.079 142.276 172.445 1.00 57.80  ? 390 SER A CB  1 
ATOM   2551  O OG  . SER A 1 425 ? 105.989 143.504 171.748 1.00 58.14  ? 390 SER A OG  1 
ATOM   2552  N N   . LYS A 1 426 ? 103.082 143.612 172.791 1.00 62.30  ? 391 LYS A N   1 
ATOM   2553  C CA  . LYS A 1 426 ? 101.965 144.081 171.980 1.00 56.78  ? 391 LYS A CA  1 
ATOM   2554  C C   . LYS A 1 426 ? 102.421 144.385 170.562 1.00 48.19  ? 391 LYS A C   1 
ATOM   2555  O O   . LYS A 1 426 ? 101.613 144.347 169.629 1.00 45.96  ? 391 LYS A O   1 
ATOM   2556  C CB  . LYS A 1 426 ? 101.324 145.316 172.616 1.00 59.95  ? 391 LYS A CB  1 
ATOM   2557  C CG  . LYS A 1 426 ? 100.583 145.030 173.915 1.00 65.00  ? 391 LYS A CG  1 
ATOM   2558  C CD  . LYS A 1 426 ? 99.980  146.294 174.518 1.00 66.08  ? 391 LYS A CD  1 
ATOM   2559  C CE  . LYS A 1 426 ? 100.892 146.926 175.564 1.00 68.89  ? 391 LYS A CE  1 
ATOM   2560  N NZ  . LYS A 1 426 ? 102.208 147.352 175.013 1.00 72.87  ? 391 LYS A NZ  1 
ATOM   2561  N N   . ILE A 1 427 ? 103.706 144.694 170.387 1.00 51.89  ? 392 ILE A N   1 
ATOM   2562  C CA  . ILE A 1 427 ? 104.256 144.832 169.046 1.00 50.70  ? 392 ILE A CA  1 
ATOM   2563  C C   . ILE A 1 427 ? 104.222 143.490 168.327 1.00 43.75  ? 392 ILE A C   1 
ATOM   2564  O O   . ILE A 1 427 ? 103.859 143.412 167.148 1.00 40.59  ? 392 ILE A O   1 
ATOM   2565  C CB  . ILE A 1 427 ? 105.682 145.409 169.104 1.00 47.61  ? 392 ILE A CB  1 
ATOM   2566  C CG1 . ILE A 1 427 ? 105.673 146.787 169.766 1.00 50.17  ? 392 ILE A CG1 1 
ATOM   2567  C CG2 . ILE A 1 427 ? 106.281 145.499 167.710 1.00 40.46  ? 392 ILE A CG2 1 
ATOM   2568  C CD1 . ILE A 1 427 ? 107.051 147.353 170.001 1.00 49.55  ? 392 ILE A CD1 1 
ATOM   2569  N N   . ASP A 1 428 ? 104.599 142.413 169.024 1.00 40.30  ? 393 ASP A N   1 
ATOM   2570  C CA  . ASP A 1 428 ? 104.532 141.083 168.425 1.00 39.26  ? 393 ASP A CA  1 
ATOM   2571  C C   . ASP A 1 428 ? 103.092 140.685 168.127 1.00 39.96  ? 393 ASP A C   1 
ATOM   2572  O O   . ASP A 1 428 ? 102.792 140.164 167.046 1.00 40.47  ? 393 ASP A O   1 
ATOM   2573  C CB  . ASP A 1 428 ? 105.181 140.058 169.357 1.00 38.61  ? 393 ASP A CB  1 
ATOM   2574  C CG  . ASP A 1 428 ? 106.656 139.866 169.080 1.00 38.87  ? 393 ASP A CG  1 
ATOM   2575  O OD1 . ASP A 1 428 ? 107.088 140.126 167.939 1.00 39.31  ? 393 ASP A OD1 1 
ATOM   2576  O OD2 . ASP A 1 428 ? 107.384 139.447 170.004 1.00 42.37  ? 393 ASP A OD2 1 
ATOM   2577  N N   . ARG A 1 429 ? 102.186 140.913 169.083 1.00 41.86  ? 394 ARG A N   1 
ATOM   2578  C CA  . ARG A 1 429 ? 100.797 140.498 168.902 1.00 37.05  ? 394 ARG A CA  1 
ATOM   2579  C C   . ARG A 1 429 ? 100.166 141.204 167.711 1.00 31.40  ? 394 ARG A C   1 
ATOM   2580  O O   . ARG A 1 429 ? 99.429  140.590 166.931 1.00 29.17  ? 394 ARG A O   1 
ATOM   2581  C CB  . ARG A 1 429 ? 99.997  140.758 170.177 1.00 49.38  ? 394 ARG A CB  1 
ATOM   2582  C CG  . ARG A 1 429 ? 100.266 139.747 171.281 1.00 59.95  ? 394 ARG A CG  1 
ATOM   2583  C CD  . ARG A 1 429 ? 99.416  140.011 172.514 1.00 70.90  ? 394 ARG A CD  1 
ATOM   2584  N NE  . ARG A 1 429 ? 97.989  139.987 172.217 1.00 79.37  ? 394 ARG A NE  1 
ATOM   2585  C CZ  . ARG A 1 429 ? 97.043  140.368 173.064 1.00 89.97  ? 394 ARG A CZ  1 
ATOM   2586  N NH1 . ARG A 1 429 ? 97.337  140.816 174.274 1.00 94.29  ? 394 ARG A NH1 1 
ATOM   2587  N NH2 . ARG A 1 429 ? 95.769  140.299 172.688 1.00 91.27  ? 394 ARG A NH2 1 
ATOM   2588  N N   . LEU A 1 430 ? 100.439 142.501 167.560 1.00 37.51  ? 395 LEU A N   1 
ATOM   2589  C CA  . LEU A 1 430 ? 99.914  143.246 166.423 1.00 36.68  ? 395 LEU A CA  1 
ATOM   2590  C C   . LEU A 1 430 ? 100.657 142.903 165.138 1.00 33.02  ? 395 LEU A C   1 
ATOM   2591  O O   . LEU A 1 430 ? 100.076 142.974 164.050 1.00 30.64  ? 395 LEU A O   1 
ATOM   2592  C CB  . LEU A 1 430 ? 99.992  144.746 166.703 1.00 35.68  ? 395 LEU A CB  1 
ATOM   2593  C CG  . LEU A 1 430 ? 99.164  145.657 165.798 1.00 35.74  ? 395 LEU A CG  1 
ATOM   2594  C CD1 . LEU A 1 430 ? 97.692  145.311 165.913 1.00 34.75  ? 395 LEU A CD1 1 
ATOM   2595  C CD2 . LEU A 1 430 ? 99.404  147.115 166.150 1.00 42.26  ? 395 LEU A CD2 1 
ATOM   2596  N N   . SER A 1 431 ? 101.936 142.533 165.241 1.00 33.02  ? 396 SER A N   1 
ATOM   2597  C CA  . SER A 1 431 ? 102.681 142.136 164.052 1.00 29.40  ? 396 SER A CA  1 
ATOM   2598  C C   . SER A 1 431 ? 102.209 140.791 163.519 1.00 30.61  ? 396 SER A C   1 
ATOM   2599  O O   . SER A 1 431 ? 102.314 140.534 162.315 1.00 29.06  ? 396 SER A O   1 
ATOM   2600  C CB  . SER A 1 431 ? 104.176 142.086 164.359 1.00 26.80  ? 396 SER A CB  1 
ATOM   2601  O OG  . SER A 1 431 ? 104.630 143.327 164.867 1.00 31.75  ? 396 SER A OG  1 
ATOM   2602  N N   . ARG A 1 432 ? 101.695 139.922 164.394 1.00 31.34  ? 397 ARG A N   1 
ATOM   2603  C CA  . ARG A 1 432 ? 101.162 138.643 163.941 1.00 25.77  ? 397 ARG A CA  1 
ATOM   2604  C C   . ARG A 1 432 ? 99.958  138.818 163.028 1.00 29.02  ? 397 ARG A C   1 
ATOM   2605  O O   . ARG A 1 432 ? 99.570  137.866 162.344 1.00 35.59  ? 397 ARG A O   1 
ATOM   2606  C CB  . ARG A 1 432 ? 100.789 137.767 165.137 1.00 27.61  ? 397 ARG A CB  1 
ATOM   2607  C CG  . ARG A 1 432 ? 101.981 137.232 165.907 1.00 28.47  ? 397 ARG A CG  1 
ATOM   2608  C CD  . ARG A 1 432 ? 101.569 136.739 167.282 1.00 28.44  ? 397 ARG A CD  1 
ATOM   2609  N NE  . ARG A 1 432 ? 102.713 136.302 168.072 1.00 28.42  ? 397 ARG A NE  1 
ATOM   2610  C CZ  . ARG A 1 432 ? 102.634 135.844 169.314 1.00 32.46  ? 397 ARG A CZ  1 
ATOM   2611  N NH1 . ARG A 1 432 ? 101.473 135.746 169.941 1.00 32.53  ? 397 ARG A NH1 1 
ATOM   2612  N NH2 . ARG A 1 432 ? 103.746 135.477 169.942 1.00 31.88  ? 397 ARG A NH2 1 
ATOM   2613  N N   . ILE A 1 433 ? 99.353  140.001 163.012 1.00 27.83  ? 398 ILE A N   1 
ATOM   2614  C CA  . ILE A 1 433 ? 98.203  140.296 162.169 1.00 27.39  ? 398 ILE A CA  1 
ATOM   2615  C C   . ILE A 1 433 ? 98.567  141.289 161.071 1.00 27.85  ? 398 ILE A C   1 
ATOM   2616  O O   . ILE A 1 433 ? 98.223  141.092 159.906 1.00 27.68  ? 398 ILE A O   1 
ATOM   2617  C CB  . ILE A 1 433 ? 97.016  140.811 163.012 1.00 25.94  ? 398 ILE A CB  1 
ATOM   2618  C CG1 . ILE A 1 433 ? 96.777  139.895 164.212 1.00 28.06  ? 398 ILE A CG1 1 
ATOM   2619  C CG2 . ILE A 1 433 ? 95.764  140.916 162.163 1.00 24.12  ? 398 ILE A CG2 1 
ATOM   2620  C CD1 . ILE A 1 433 ? 95.739  140.414 165.180 1.00 28.66  ? 398 ILE A CD1 1 
ATOM   2621  N N   . ALA A 1 434 ? 99.259  142.372 161.434 1.00 27.14  ? 399 ALA A N   1 
ATOM   2622  C CA  . ALA A 1 434 ? 99.567  143.421 160.466 1.00 22.35  ? 399 ALA A CA  1 
ATOM   2623  C C   . ALA A 1 434 ? 100.465 142.898 159.352 1.00 24.17  ? 399 ALA A C   1 
ATOM   2624  O O   . ALA A 1 434 ? 100.223 143.159 158.169 1.00 27.47  ? 399 ALA A O   1 
ATOM   2625  C CB  . ALA A 1 434 ? 100.219 144.610 161.170 1.00 20.20  ? 399 ALA A CB  1 
ATOM   2626  N N   . PHE A 1 435 ? 101.514 142.152 159.716 1.00 24.19  ? 400 PHE A N   1 
ATOM   2627  C CA  . PHE A 1 435 ? 102.454 141.669 158.704 1.00 23.92  ? 400 PHE A CA  1 
ATOM   2628  C C   . PHE A 1 435 ? 101.812 140.680 157.738 1.00 24.96  ? 400 PHE A C   1 
ATOM   2629  O O   . PHE A 1 435 ? 101.954 140.868 156.516 1.00 25.95  ? 400 PHE A O   1 
ATOM   2630  C CB  . PHE A 1 435 ? 103.699 141.089 159.382 1.00 23.63  ? 400 PHE A CB  1 
ATOM   2631  C CG  . PHE A 1 435 ? 104.724 142.121 159.750 1.00 25.76  ? 400 PHE A CG  1 
ATOM   2632  C CD1 . PHE A 1 435 ? 104.485 143.015 160.779 1.00 25.79  ? 400 PHE A CD1 1 
ATOM   2633  C CD2 . PHE A 1 435 ? 105.921 142.206 159.060 1.00 25.15  ? 400 PHE A CD2 1 
ATOM   2634  C CE1 . PHE A 1 435 ? 105.424 143.966 161.120 1.00 26.57  ? 400 PHE A CE1 1 
ATOM   2635  C CE2 . PHE A 1 435 ? 106.862 143.158 159.396 1.00 25.83  ? 400 PHE A CE2 1 
ATOM   2636  C CZ  . PHE A 1 435 ? 106.613 144.038 160.428 1.00 24.70  ? 400 PHE A CZ  1 
ATOM   2637  N N   . PRO A 1 436 ? 101.123 139.618 158.183 1.00 22.11  ? 401 PRO A N   1 
ATOM   2638  C CA  . PRO A 1 436 ? 100.434 138.755 157.206 1.00 21.85  ? 401 PRO A CA  1 
ATOM   2639  C C   . PRO A 1 436 ? 99.401  139.493 156.370 1.00 25.88  ? 401 PRO A C   1 
ATOM   2640  O O   . PRO A 1 436 ? 99.243  139.192 155.181 1.00 27.55  ? 401 PRO A O   1 
ATOM   2641  C CB  . PRO A 1 436 ? 99.788  137.676 158.085 1.00 21.64  ? 401 PRO A CB  1 
ATOM   2642  C CG  . PRO A 1 436 ? 100.595 137.653 159.316 1.00 21.22  ? 401 PRO A CG  1 
ATOM   2643  C CD  . PRO A 1 436 ? 101.042 139.060 159.545 1.00 20.87  ? 401 PRO A CD  1 
ATOM   2644  N N   . LEU A 1 437 ? 98.690  140.455 156.962 1.00 23.86  ? 402 LEU A N   1 
ATOM   2645  C CA  . LEU A 1 437 ? 97.648  141.169 156.231 1.00 23.47  ? 402 LEU A CA  1 
ATOM   2646  C C   . LEU A 1 437 ? 98.243  142.088 155.171 1.00 24.19  ? 402 LEU A C   1 
ATOM   2647  O O   . LEU A 1 437 ? 97.780  142.106 154.026 1.00 27.72  ? 402 LEU A O   1 
ATOM   2648  C CB  . LEU A 1 437 ? 96.776  141.966 157.201 1.00 23.36  ? 402 LEU A CB  1 
ATOM   2649  C CG  . LEU A 1 437 ? 95.537  142.629 156.598 1.00 27.46  ? 402 LEU A CG  1 
ATOM   2650  C CD1 . LEU A 1 437 ? 94.562  141.583 156.085 1.00 26.11  ? 402 LEU A CD1 1 
ATOM   2651  C CD2 . LEU A 1 437 ? 94.869  143.540 157.616 1.00 33.91  ? 402 LEU A CD2 1 
ATOM   2652  N N   . LEU A 1 438 ? 99.271  142.861 155.532 1.00 22.25  ? 403 LEU A N   1 
ATOM   2653  C CA  . LEU A 1 438 ? 99.889  143.756 154.558 1.00 21.91  ? 403 LEU A CA  1 
ATOM   2654  C C   . LEU A 1 438 ? 100.506 142.972 153.408 1.00 24.93  ? 403 LEU A C   1 
ATOM   2655  O O   . LEU A 1 438 ? 100.406 143.382 152.245 1.00 25.84  ? 403 LEU A O   1 
ATOM   2656  C CB  . LEU A 1 438 ? 100.940 144.635 155.231 1.00 16.92  ? 403 LEU A CB  1 
ATOM   2657  C CG  . LEU A 1 438 ? 100.436 145.677 156.230 1.00 16.77  ? 403 LEU A CG  1 
ATOM   2658  C CD1 . LEU A 1 438 ? 101.605 146.323 156.957 1.00 16.80  ? 403 LEU A CD1 1 
ATOM   2659  C CD2 . LEU A 1 438 ? 99.589  146.727 155.534 1.00 17.47  ? 403 LEU A CD2 1 
ATOM   2660  N N   . PHE A 1 439 ? 101.153 141.844 153.707 1.00 22.16  ? 404 PHE A N   1 
ATOM   2661  C CA  . PHE A 1 439 ? 101.708 141.030 152.633 1.00 20.71  ? 404 PHE A CA  1 
ATOM   2662  C C   . PHE A 1 439 ? 100.600 140.408 151.796 1.00 23.17  ? 404 PHE A C   1 
ATOM   2663  O O   . PHE A 1 439 ? 100.721 140.314 150.569 1.00 27.16  ? 404 PHE A O   1 
ATOM   2664  C CB  . PHE A 1 439 ? 102.626 139.947 153.197 1.00 21.11  ? 404 PHE A CB  1 
ATOM   2665  C CG  . PHE A 1 439 ? 103.410 139.212 152.144 1.00 21.79  ? 404 PHE A CG  1 
ATOM   2666  C CD1 . PHE A 1 439 ? 104.306 139.883 151.332 1.00 21.33  ? 404 PHE A CD1 1 
ATOM   2667  C CD2 . PHE A 1 439 ? 103.245 137.849 151.965 1.00 18.69  ? 404 PHE A CD2 1 
ATOM   2668  C CE1 . PHE A 1 439 ? 105.024 139.209 150.362 1.00 19.95  ? 404 PHE A CE1 1 
ATOM   2669  C CE2 . PHE A 1 439 ? 103.961 137.172 150.998 1.00 15.45  ? 404 PHE A CE2 1 
ATOM   2670  C CZ  . PHE A 1 439 ? 104.850 137.853 150.196 1.00 18.30  ? 404 PHE A CZ  1 
ATOM   2671  N N   . GLY A 1 440 ? 99.517  139.965 152.440 1.00 20.54  ? 405 GLY A N   1 
ATOM   2672  C CA  . GLY A 1 440 ? 98.384  139.462 151.683 1.00 22.50  ? 405 GLY A CA  1 
ATOM   2673  C C   . GLY A 1 440 ? 97.774  140.518 150.783 1.00 26.68  ? 405 GLY A C   1 
ATOM   2674  O O   . GLY A 1 440 ? 97.441  140.245 149.627 1.00 29.12  ? 405 GLY A O   1 
ATOM   2675  N N   . ILE A 1 441 ? 97.618  141.741 151.299 1.00 26.35  ? 406 ILE A N   1 
ATOM   2676  C CA  . ILE A 1 441 ? 97.088  142.830 150.482 1.00 28.96  ? 406 ILE A CA  1 
ATOM   2677  C C   . ILE A 1 441 ? 98.030  143.125 149.324 1.00 31.36  ? 406 ILE A C   1 
ATOM   2678  O O   . ILE A 1 441 ? 97.598  143.307 148.179 1.00 32.94  ? 406 ILE A O   1 
ATOM   2679  C CB  . ILE A 1 441 ? 96.831  144.080 151.342 1.00 27.52  ? 406 ILE A CB  1 
ATOM   2680  C CG1 . ILE A 1 441 ? 95.672  143.829 152.309 1.00 27.95  ? 406 ILE A CG1 1 
ATOM   2681  C CG2 . ILE A 1 441 ? 96.544  145.287 150.465 1.00 25.39  ? 406 ILE A CG2 1 
ATOM   2682  C CD1 . ILE A 1 441 ? 95.289  145.038 153.128 1.00 25.77  ? 406 ILE A CD1 1 
ATOM   2683  N N   . PHE A 1 442 ? 99.336  143.181 149.606 1.00 28.38  ? 407 PHE A N   1 
ATOM   2684  C CA  . PHE A 1 442 ? 100.302 143.446 148.546 1.00 25.19  ? 407 PHE A CA  1 
ATOM   2685  C C   . PHE A 1 442 ? 100.234 142.385 147.460 1.00 29.30  ? 407 PHE A C   1 
ATOM   2686  O O   . PHE A 1 442 ? 100.489 142.678 146.287 1.00 31.54  ? 407 PHE A O   1 
ATOM   2687  C CB  . PHE A 1 442 ? 101.718 143.518 149.113 1.00 21.38  ? 407 PHE A CB  1 
ATOM   2688  C CG  . PHE A 1 442 ? 102.788 143.349 148.072 1.00 25.29  ? 407 PHE A CG  1 
ATOM   2689  C CD1 . PHE A 1 442 ? 103.050 144.352 147.158 1.00 25.43  ? 407 PHE A CD1 1 
ATOM   2690  C CD2 . PHE A 1 442 ? 103.520 142.176 147.998 1.00 24.98  ? 407 PHE A CD2 1 
ATOM   2691  C CE1 . PHE A 1 442 ? 104.027 144.192 146.195 1.00 20.76  ? 407 PHE A CE1 1 
ATOM   2692  C CE2 . PHE A 1 442 ? 104.497 142.012 147.038 1.00 21.30  ? 407 PHE A CE2 1 
ATOM   2693  C CZ  . PHE A 1 442 ? 104.750 143.020 146.136 1.00 18.55  ? 407 PHE A CZ  1 
ATOM   2694  N N   . ASN A 1 443 ? 99.882  141.154 147.826 1.00 29.02  ? 408 ASN A N   1 
ATOM   2695  C CA  . ASN A 1 443 ? 99.832  140.091 146.834 1.00 30.63  ? 408 ASN A CA  1 
ATOM   2696  C C   . ASN A 1 443 ? 98.593  140.222 145.962 1.00 36.45  ? 408 ASN A C   1 
ATOM   2697  O O   . ASN A 1 443 ? 98.651  139.964 144.755 1.00 39.10  ? 408 ASN A O   1 
ATOM   2698  C CB  . ASN A 1 443 ? 99.876  138.729 147.521 1.00 27.77  ? 408 ASN A CB  1 
ATOM   2699  C CG  . ASN A 1 443 ? 101.287 138.301 147.860 1.00 28.33  ? 408 ASN A CG  1 
ATOM   2700  O OD1 . ASN A 1 443 ? 101.947 137.621 147.075 1.00 31.04  ? 408 ASN A OD1 1 
ATOM   2701  N ND2 . ASN A 1 443 ? 101.762 138.705 149.031 1.00 25.32  ? 408 ASN A ND2 1 
ATOM   2702  N N   . LEU A 1 444 ? 97.468  140.635 146.550 1.00 32.77  ? 409 LEU A N   1 
ATOM   2703  C CA  . LEU A 1 444 ? 96.277  140.884 145.748 1.00 32.89  ? 409 LEU A CA  1 
ATOM   2704  C C   . LEU A 1 444 ? 96.511  142.026 144.769 1.00 33.23  ? 409 LEU A C   1 
ATOM   2705  O O   . LEU A 1 444 ? 96.137  141.933 143.596 1.00 36.86  ? 409 LEU A O   1 
ATOM   2706  C CB  . LEU A 1 444 ? 95.082  141.184 146.651 1.00 30.37  ? 409 LEU A CB  1 
ATOM   2707  C CG  . LEU A 1 444 ? 94.520  139.986 147.416 1.00 35.60  ? 409 LEU A CG  1 
ATOM   2708  C CD1 . LEU A 1 444 ? 93.484  140.431 148.436 1.00 39.01  ? 409 LEU A CD1 1 
ATOM   2709  C CD2 . LEU A 1 444 ? 93.931  138.967 146.453 1.00 32.32  ? 409 LEU A CD2 1 
ATOM   2710  N N   . VAL A 1 445 ? 97.136  143.110 145.233 1.00 29.84  ? 410 VAL A N   1 
ATOM   2711  C CA  . VAL A 1 445 ? 97.409  144.243 144.354 1.00 32.60  ? 410 VAL A CA  1 
ATOM   2712  C C   . VAL A 1 445 ? 98.383  143.843 143.253 1.00 34.23  ? 410 VAL A C   1 
ATOM   2713  O O   . VAL A 1 445 ? 98.193  144.185 142.081 1.00 37.10  ? 410 VAL A O   1 
ATOM   2714  C CB  . VAL A 1 445 ? 97.938  145.435 145.171 1.00 31.27  ? 410 VAL A CB  1 
ATOM   2715  C CG1 . VAL A 1 445 ? 98.358  146.567 144.248 1.00 30.52  ? 410 VAL A CG1 1 
ATOM   2716  C CG2 . VAL A 1 445 ? 96.883  145.907 146.156 1.00 31.78  ? 410 VAL A CG2 1 
ATOM   2717  N N   . TYR A 1 446 ? 99.434  143.104 143.611 1.00 29.99  ? 411 TYR A N   1 
ATOM   2718  C CA  . TYR A 1 446 ? 100.427 142.691 142.624 1.00 30.18  ? 411 TYR A CA  1 
ATOM   2719  C C   . TYR A 1 446 ? 99.828  141.720 141.613 1.00 33.21  ? 411 TYR A C   1 
ATOM   2720  O O   . TYR A 1 446 ? 99.966  141.909 140.399 1.00 33.71  ? 411 TYR A O   1 
ATOM   2721  C CB  . TYR A 1 446 ? 101.636 142.074 143.330 1.00 25.65  ? 411 TYR A CB  1 
ATOM   2722  C CG  . TYR A 1 446 ? 102.749 141.633 142.404 1.00 25.25  ? 411 TYR A CG  1 
ATOM   2723  C CD1 . TYR A 1 446 ? 102.739 140.376 141.817 1.00 24.20  ? 411 TYR A CD1 1 
ATOM   2724  C CD2 . TYR A 1 446 ? 103.809 142.480 142.115 1.00 22.94  ? 411 TYR A CD2 1 
ATOM   2725  C CE1 . TYR A 1 446 ? 103.750 139.976 140.974 1.00 20.30  ? 411 TYR A CE1 1 
ATOM   2726  C CE2 . TYR A 1 446 ? 104.825 142.087 141.272 1.00 22.53  ? 411 TYR A CE2 1 
ATOM   2727  C CZ  . TYR A 1 446 ? 104.790 140.834 140.704 1.00 21.44  ? 411 TYR A CZ  1 
ATOM   2728  O OH  . TYR A 1 446 ? 105.801 140.434 139.863 1.00 27.46  ? 411 TYR A OH  1 
ATOM   2729  N N   . TRP A 1 447 ? 99.158  140.672 142.097 1.00 31.58  ? 412 TRP A N   1 
ATOM   2730  C CA  . TRP A 1 447 ? 98.686  139.621 141.202 1.00 34.01  ? 412 TRP A CA  1 
ATOM   2731  C C   . TRP A 1 447 ? 97.496  140.074 140.364 1.00 38.49  ? 412 TRP A C   1 
ATOM   2732  O O   . TRP A 1 447 ? 97.371  139.665 139.205 1.00 42.45  ? 412 TRP A O   1 
ATOM   2733  C CB  . TRP A 1 447 ? 98.339  138.367 142.004 1.00 31.22  ? 412 TRP A CB  1 
ATOM   2734  C CG  . TRP A 1 447 ? 99.551  137.650 142.530 1.00 35.01  ? 412 TRP A CG  1 
ATOM   2735  C CD1 . TRP A 1 447 ? 99.863  137.420 143.837 1.00 35.03  ? 412 TRP A CD1 1 
ATOM   2736  C CD2 . TRP A 1 447 ? 100.610 137.070 141.758 1.00 33.76  ? 412 TRP A CD2 1 
ATOM   2737  N NE1 . TRP A 1 447 ? 101.050 136.736 143.929 1.00 37.91  ? 412 TRP A NE1 1 
ATOM   2738  C CE2 . TRP A 1 447 ? 101.529 136.508 142.666 1.00 36.19  ? 412 TRP A CE2 1 
ATOM   2739  C CE3 . TRP A 1 447 ? 100.871 136.970 140.389 1.00 24.40  ? 412 TRP A CE3 1 
ATOM   2740  C CZ2 . TRP A 1 447 ? 102.687 135.858 142.249 1.00 28.23  ? 412 TRP A CZ2 1 
ATOM   2741  C CZ3 . TRP A 1 447 ? 102.020 136.324 139.979 1.00 22.31  ? 412 TRP A CZ3 1 
ATOM   2742  C CH2 . TRP A 1 447 ? 102.914 135.777 140.905 1.00 23.35  ? 412 TRP A CH2 1 
ATOM   2743  N N   . ALA A 1 448 ? 96.622  140.918 140.916 1.00 36.06  ? 413 ALA A N   1 
ATOM   2744  C CA  . ALA A 1 448 ? 95.523  141.456 140.119 1.00 35.22  ? 413 ALA A CA  1 
ATOM   2745  C C   . ALA A 1 448 ? 96.030  142.418 139.053 1.00 38.71  ? 413 ALA A C   1 
ATOM   2746  O O   . ALA A 1 448 ? 95.485  142.466 137.944 1.00 44.06  ? 413 ALA A O   1 
ATOM   2747  C CB  . ALA A 1 448 ? 94.495  142.144 141.016 1.00 28.42  ? 413 ALA A CB  1 
ATOM   2748  N N   . THR A 1 449 ? 97.067  143.197 139.370 1.00 35.74  ? 414 THR A N   1 
ATOM   2749  C CA  . THR A 1 449 ? 97.561  144.195 138.426 1.00 40.12  ? 414 THR A CA  1 
ATOM   2750  C C   . THR A 1 449 ? 98.115  143.542 137.165 1.00 43.73  ? 414 THR A C   1 
ATOM   2751  O O   . THR A 1 449 ? 97.857  144.011 136.050 1.00 45.73  ? 414 THR A O   1 
ATOM   2752  C CB  . THR A 1 449 ? 98.631  145.062 139.091 1.00 35.95  ? 414 THR A CB  1 
ATOM   2753  O OG1 . THR A 1 449 ? 98.025  145.883 140.096 1.00 38.79  ? 414 THR A OG1 1 
ATOM   2754  C CG2 . THR A 1 449 ? 99.320  145.952 138.068 1.00 32.25  ? 414 THR A CG2 1 
ATOM   2755  N N   . TYR A 1 450 ? 98.862  142.449 137.314 1.00 39.79  ? 415 TYR A N   1 
ATOM   2756  C CA  . TYR A 1 450 ? 99.593  141.873 136.193 1.00 36.81  ? 415 TYR A CA  1 
ATOM   2757  C C   . TYR A 1 450 ? 98.868  140.719 135.518 1.00 36.27  ? 415 TYR A C   1 
ATOM   2758  O O   . TYR A 1 450 ? 99.088  140.482 134.327 1.00 37.07  ? 415 TYR A O   1 
ATOM   2759  C CB  . TYR A 1 450 ? 100.974 141.393 136.651 1.00 32.03  ? 415 TYR A CB  1 
ATOM   2760  C CG  . TYR A 1 450 ? 101.925 142.513 136.999 1.00 28.65  ? 415 TYR A CG  1 
ATOM   2761  C CD1 . TYR A 1 450 ? 102.520 143.276 136.004 1.00 32.82  ? 415 TYR A CD1 1 
ATOM   2762  C CD2 . TYR A 1 450 ? 102.236 142.802 138.318 1.00 27.01  ? 415 TYR A CD2 1 
ATOM   2763  C CE1 . TYR A 1 450 ? 103.389 144.299 136.314 1.00 31.52  ? 415 TYR A CE1 1 
ATOM   2764  C CE2 . TYR A 1 450 ? 103.108 143.823 138.637 1.00 28.75  ? 415 TYR A CE2 1 
ATOM   2765  C CZ  . TYR A 1 450 ? 103.681 144.568 137.632 1.00 28.73  ? 415 TYR A CZ  1 
ATOM   2766  O OH  . TYR A 1 450 ? 104.551 145.586 137.943 1.00 25.50  ? 415 TYR A OH  1 
ATOM   2767  N N   . LEU A 1 451 ? 98.020  139.993 136.238 1.00 36.33  ? 416 LEU A N   1 
ATOM   2768  C CA  . LEU A 1 451 ? 97.261  138.905 135.631 1.00 40.57  ? 416 LEU A CA  1 
ATOM   2769  C C   . LEU A 1 451 ? 96.046  139.446 134.885 1.00 45.85  ? 416 LEU A C   1 
ATOM   2770  O O   . LEU A 1 451 ? 95.556  140.536 135.183 1.00 40.36  ? 416 LEU A O   1 
ATOM   2771  C CB  . LEU A 1 451 ? 96.824  137.889 136.687 1.00 37.25  ? 416 LEU A CB  1 
ATOM   2772  C CG  . LEU A 1 451 ? 97.941  137.069 137.333 1.00 34.00  ? 416 LEU A CG  1 
ATOM   2773  C CD1 . LEU A 1 451 ? 97.367  136.093 138.344 1.00 34.32  ? 416 LEU A CD1 1 
ATOM   2774  C CD2 . LEU A 1 451 ? 98.740  136.333 136.272 1.00 35.37  ? 416 LEU A CD2 1 
ATOM   2775  N N   . MET B 2 34  ? 147.882 105.326 82.110  1.00 100.96 ? 9   MET B N   1 
ATOM   2776  C CA  . MET B 2 34  ? 146.910 106.357 82.448  1.00 100.61 ? 9   MET B CA  1 
ATOM   2777  C C   . MET B 2 34  ? 146.318 106.998 81.198  1.00 100.82 ? 9   MET B C   1 
ATOM   2778  O O   . MET B 2 34  ? 145.337 107.737 81.279  1.00 94.26  ? 9   MET B O   1 
ATOM   2779  C CB  . MET B 2 34  ? 147.549 107.431 83.328  1.00 103.61 ? 9   MET B CB  1 
ATOM   2780  C CG  . MET B 2 34  ? 148.003 106.934 84.687  1.00 107.13 ? 9   MET B CG  1 
ATOM   2781  S SD  . MET B 2 34  ? 148.830 108.228 85.626  1.00 116.57 ? 9   MET B SD  1 
ATOM   2782  C CE  . MET B 2 34  ? 147.551 109.478 85.649  1.00 102.19 ? 9   MET B CE  1 
ATOM   2783  N N   . SER B 2 35  ? 146.924 106.717 80.043  1.00 108.96 ? 10  SER B N   1 
ATOM   2784  C CA  . SER B 2 35  ? 146.437 107.297 78.795  1.00 106.64 ? 10  SER B CA  1 
ATOM   2785  C C   . SER B 2 35  ? 145.021 106.820 78.498  1.00 107.57 ? 10  SER B C   1 
ATOM   2786  O O   . SER B 2 35  ? 144.141 107.618 78.155  1.00 107.16 ? 10  SER B O   1 
ATOM   2787  C CB  . SER B 2 35  ? 147.382 106.943 77.647  1.00 99.97  ? 10  SER B CB  1 
ATOM   2788  O OG  . SER B 2 35  ? 148.703 107.378 77.920  1.00 92.62  ? 10  SER B OG  1 
ATOM   2789  N N   . PHE B 2 36  ? 144.787 105.512 78.619  1.00 104.06 ? 11  PHE B N   1 
ATOM   2790  C CA  . PHE B 2 36  ? 143.463 104.965 78.348  1.00 105.60 ? 11  PHE B CA  1 
ATOM   2791  C C   . PHE B 2 36  ? 142.442 105.467 79.362  1.00 105.14 ? 11  PHE B C   1 
ATOM   2792  O O   . PHE B 2 36  ? 141.303 105.786 79.000  1.00 104.41 ? 11  PHE B O   1 
ATOM   2793  C CB  . PHE B 2 36  ? 143.516 103.438 78.349  1.00 106.34 ? 11  PHE B CB  1 
ATOM   2794  C CG  . PHE B 2 36  ? 142.177 102.787 78.165  1.00 113.67 ? 11  PHE B CG  1 
ATOM   2795  C CD1 . PHE B 2 36  ? 141.358 103.142 77.106  1.00 113.18 ? 11  PHE B CD1 1 
ATOM   2796  C CD2 . PHE B 2 36  ? 141.733 101.823 79.055  1.00 109.91 ? 11  PHE B CD2 1 
ATOM   2797  C CE1 . PHE B 2 36  ? 140.124 102.545 76.935  1.00 113.24 ? 11  PHE B CE1 1 
ATOM   2798  C CE2 . PHE B 2 36  ? 140.500 101.223 78.890  1.00 105.78 ? 11  PHE B CE2 1 
ATOM   2799  C CZ  . PHE B 2 36  ? 139.694 101.584 77.828  1.00 108.17 ? 11  PHE B CZ  1 
ATOM   2800  N N   . VAL B 2 37  ? 142.834 105.542 80.638  1.00 103.29 ? 12  VAL B N   1 
ATOM   2801  C CA  . VAL B 2 37  ? 141.922 106.009 81.680  1.00 101.16 ? 12  VAL B CA  1 
ATOM   2802  C C   . VAL B 2 37  ? 141.547 107.468 81.455  1.00 96.65  ? 12  VAL B C   1 
ATOM   2803  O O   . VAL B 2 37  ? 140.386 107.859 81.629  1.00 94.10  ? 12  VAL B O   1 
ATOM   2804  C CB  . VAL B 2 37  ? 142.547 105.796 83.072  1.00 93.84  ? 12  VAL B CB  1 
ATOM   2805  C CG1 . VAL B 2 37  ? 141.625 106.331 84.157  1.00 73.06  ? 12  VAL B CG1 1 
ATOM   2806  C CG2 . VAL B 2 37  ? 142.846 104.324 83.300  1.00 92.05  ? 12  VAL B CG2 1 
ATOM   2807  N N   . LYS B 2 38  ? 142.520 108.297 81.067  1.00 97.20  ? 13  LYS B N   1 
ATOM   2808  C CA  . LYS B 2 38  ? 142.236 109.710 80.841  1.00 97.52  ? 13  LYS B CA  1 
ATOM   2809  C C   . LYS B 2 38  ? 141.196 109.891 79.744  1.00 98.10  ? 13  LYS B C   1 
ATOM   2810  O O   . LYS B 2 38  ? 140.299 110.733 79.859  1.00 95.04  ? 13  LYS B O   1 
ATOM   2811  C CB  . LYS B 2 38  ? 143.525 110.454 80.491  1.00 101.20 ? 13  LYS B CB  1 
ATOM   2812  C CG  . LYS B 2 38  ? 143.317 111.904 80.089  1.00 99.88  ? 13  LYS B CG  1 
ATOM   2813  C CD  . LYS B 2 38  ? 144.638 112.652 80.036  1.00 101.81 ? 13  LYS B CD  1 
ATOM   2814  C CE  . LYS B 2 38  ? 144.460 114.044 79.454  1.00 100.29 ? 13  LYS B CE  1 
ATOM   2815  N NZ  . LYS B 2 38  ? 143.398 114.808 80.167  1.00 101.39 ? 13  LYS B NZ  1 
ATOM   2816  N N   . GLU B 2 39  ? 141.298 109.102 78.673  1.00 100.69 ? 14  GLU B N   1 
ATOM   2817  C CA  . GLU B 2 39  ? 140.304 109.156 77.607  1.00 98.68  ? 14  GLU B CA  1 
ATOM   2818  C C   . GLU B 2 39  ? 138.929 108.743 78.119  1.00 93.53  ? 14  GLU B C   1 
ATOM   2819  O O   . GLU B 2 39  ? 137.920 109.391 77.819  1.00 94.24  ? 14  GLU B O   1 
ATOM   2820  C CB  . GLU B 2 39  ? 140.740 108.266 76.444  1.00 107.40 ? 14  GLU B CB  1 
ATOM   2821  C CG  . GLU B 2 39  ? 142.046 108.694 75.799  1.00 116.61 ? 14  GLU B CG  1 
ATOM   2822  C CD  . GLU B 2 39  ? 142.482 107.759 74.689  1.00 130.89 ? 14  GLU B CD  1 
ATOM   2823  O OE1 . GLU B 2 39  ? 141.703 106.849 74.336  1.00 135.58 ? 14  GLU B OE1 1 
ATOM   2824  O OE2 . GLU B 2 39  ? 143.605 107.934 74.171  1.00 130.05 ? 14  GLU B OE2 1 
ATOM   2825  N N   . THR B 2 40  ? 138.874 107.656 78.893  1.00 90.88  ? 15  THR B N   1 
ATOM   2826  C CA  . THR B 2 40  ? 137.596 107.151 79.388  1.00 88.72  ? 15  THR B CA  1 
ATOM   2827  C C   . THR B 2 40  ? 136.902 108.164 80.292  1.00 86.24  ? 15  THR B C   1 
ATOM   2828  O O   . THR B 2 40  ? 135.695 108.395 80.161  1.00 84.05  ? 15  THR B O   1 
ATOM   2829  C CB  . THR B 2 40  ? 137.810 105.831 80.129  1.00 87.86  ? 15  THR B CB  1 
ATOM   2830  O OG1 . THR B 2 40  ? 138.481 104.903 79.267  1.00 95.76  ? 15  THR B OG1 1 
ATOM   2831  C CG2 . THR B 2 40  ? 136.479 105.238 80.559  1.00 75.56  ? 15  THR B CG2 1 
ATOM   2832  N N   . VAL B 2 41  ? 137.645 108.778 81.217  1.00 87.18  ? 16  VAL B N   1 
ATOM   2833  C CA  . VAL B 2 41  ? 137.037 109.727 82.148  1.00 81.86  ? 16  VAL B CA  1 
ATOM   2834  C C   . VAL B 2 41  ? 136.510 110.943 81.395  1.00 82.74  ? 16  VAL B C   1 
ATOM   2835  O O   . VAL B 2 41  ? 135.391 111.409 81.637  1.00 78.77  ? 16  VAL B O   1 
ATOM   2836  C CB  . VAL B 2 41  ? 138.043 110.129 83.242  1.00 71.29  ? 16  VAL B CB  1 
ATOM   2837  C CG1 . VAL B 2 41  ? 137.478 111.249 84.097  1.00 52.90  ? 16  VAL B CG1 1 
ATOM   2838  C CG2 . VAL B 2 41  ? 138.390 108.926 84.102  1.00 70.72  ? 16  VAL B CG2 1 
ATOM   2839  N N   . ASP B 2 42  ? 137.311 111.474 80.468  1.00 85.85  ? 17  ASP B N   1 
ATOM   2840  C CA  . ASP B 2 42  ? 136.863 112.610 79.670  1.00 82.57  ? 17  ASP B CA  1 
ATOM   2841  C C   . ASP B 2 42  ? 135.679 112.234 78.790  1.00 82.40  ? 17  ASP B C   1 
ATOM   2842  O O   . ASP B 2 42  ? 134.820 113.078 78.509  1.00 81.45  ? 17  ASP B O   1 
ATOM   2843  C CB  . ASP B 2 42  ? 138.010 113.151 78.816  1.00 88.34  ? 17  ASP B CB  1 
ATOM   2844  C CG  . ASP B 2 42  ? 139.207 113.570 79.646  1.00 91.63  ? 17  ASP B CG  1 
ATOM   2845  O OD1 . ASP B 2 42  ? 139.005 114.075 80.770  1.00 93.67  ? 17  ASP B OD1 1 
ATOM   2846  O OD2 . ASP B 2 42  ? 140.350 113.404 79.170  1.00 91.28  ? 17  ASP B OD2 1 
ATOM   2847  N N   . LYS B 2 43  ? 135.621 110.977 78.343  1.00 84.37  ? 18  LYS B N   1 
ATOM   2848  C CA  . LYS B 2 43  ? 134.507 110.532 77.514  1.00 83.98  ? 18  LYS B CA  1 
ATOM   2849  C C   . LYS B 2 43  ? 133.192 110.584 78.281  1.00 85.68  ? 18  LYS B C   1 
ATOM   2850  O O   . LYS B 2 43  ? 132.166 111.003 77.732  1.00 89.33  ? 18  LYS B O   1 
ATOM   2851  C CB  . LYS B 2 43  ? 134.771 109.117 77.001  1.00 81.56  ? 18  LYS B CB  1 
ATOM   2852  C CG  . LYS B 2 43  ? 133.713 108.594 76.046  1.00 82.85  ? 18  LYS B CG  1 
ATOM   2853  C CD  . LYS B 2 43  ? 134.062 107.203 75.547  1.00 88.10  ? 18  LYS B CD  1 
ATOM   2854  C CE  . LYS B 2 43  ? 132.994 106.673 74.605  1.00 86.27  ? 18  LYS B CE  1 
ATOM   2855  N NZ  . LYS B 2 43  ? 133.324 105.313 74.096  1.00 89.97  ? 18  LYS B NZ  1 
ATOM   2856  N N   . LEU B 2 44  ? 133.199 110.154 79.545  1.00 79.81  ? 19  LEU B N   1 
ATOM   2857  C CA  . LEU B 2 44  ? 131.962 110.120 80.320  1.00 76.59  ? 19  LEU B CA  1 
ATOM   2858  C C   . LEU B 2 44  ? 131.383 111.517 80.497  1.00 80.64  ? 19  LEU B C   1 
ATOM   2859  O O   . LEU B 2 44  ? 130.171 111.718 80.355  1.00 80.57  ? 19  LEU B O   1 
ATOM   2860  C CB  . LEU B 2 44  ? 132.211 109.469 81.680  1.00 70.17  ? 19  LEU B CB  1 
ATOM   2861  C CG  . LEU B 2 44  ? 132.580 107.985 81.678  1.00 71.89  ? 19  LEU B CG  1 
ATOM   2862  C CD1 . LEU B 2 44  ? 132.877 107.511 83.091  1.00 63.42  ? 19  LEU B CD1 1 
ATOM   2863  C CD2 . LEU B 2 44  ? 131.467 107.157 81.055  1.00 69.87  ? 19  LEU B CD2 1 
ATOM   2864  N N   . LEU B 2 45  ? 132.232 112.497 80.799  1.00 80.28  ? 20  LEU B N   1 
ATOM   2865  C CA  . LEU B 2 45  ? 131.781 113.852 81.085  1.00 77.91  ? 20  LEU B CA  1 
ATOM   2866  C C   . LEU B 2 45  ? 131.556 114.685 79.830  1.00 78.63  ? 20  LEU B C   1 
ATOM   2867  O O   . LEU B 2 45  ? 131.124 115.837 79.944  1.00 74.92  ? 20  LEU B O   1 
ATOM   2868  C CB  . LEU B 2 45  ? 132.782 114.557 82.002  1.00 74.82  ? 20  LEU B CB  1 
ATOM   2869  C CG  . LEU B 2 45  ? 132.868 113.986 83.417  1.00 68.43  ? 20  LEU B CG  1 
ATOM   2870  C CD1 . LEU B 2 45  ? 134.104 114.494 84.130  1.00 73.28  ? 20  LEU B CD1 1 
ATOM   2871  C CD2 . LEU B 2 45  ? 131.619 114.338 84.198  1.00 64.33  ? 20  LEU B CD2 1 
ATOM   2872  N N   . LYS B 2 46  ? 131.832 114.142 78.648  1.00 83.65  ? 21  LYS B N   1 
ATOM   2873  C CA  . LYS B 2 46  ? 131.599 114.866 77.405  1.00 85.16  ? 21  LYS B CA  1 
ATOM   2874  C C   . LYS B 2 46  ? 130.107 114.854 77.100  1.00 84.78  ? 21  LYS B C   1 
ATOM   2875  O O   . LYS B 2 46  ? 129.522 113.790 76.873  1.00 78.77  ? 21  LYS B O   1 
ATOM   2876  C CB  . LYS B 2 46  ? 132.391 114.237 76.262  1.00 84.33  ? 21  LYS B CB  1 
ATOM   2877  C CG  . LYS B 2 46  ? 132.302 115.005 74.953  1.00 89.06  ? 21  LYS B CG  1 
ATOM   2878  C CD  . LYS B 2 46  ? 133.090 114.317 73.850  1.00 93.28  ? 21  LYS B CD  1 
ATOM   2879  C CE  . LYS B 2 46  ? 132.971 115.072 72.537  1.00 91.55  ? 21  LYS B CE  1 
ATOM   2880  N NZ  . LYS B 2 46  ? 133.737 114.412 71.443  1.00 87.35  ? 21  LYS B NZ  1 
ATOM   2881  N N   . GLY B 2 47  ? 129.493 116.036 77.092  1.00 87.85  ? 22  GLY B N   1 
ATOM   2882  C CA  . GLY B 2 47  ? 128.069 116.142 76.873  1.00 84.49  ? 22  GLY B CA  1 
ATOM   2883  C C   . GLY B 2 47  ? 127.225 115.869 78.098  1.00 88.32  ? 22  GLY B C   1 
ATOM   2884  O O   . GLY B 2 47  ? 125.992 115.903 78.000  1.00 91.27  ? 22  GLY B O   1 
ATOM   2885  N N   . TYR B 2 48  ? 127.850 115.591 79.241  1.00 84.18  ? 23  TYR B N   1 
ATOM   2886  C CA  . TYR B 2 48  ? 127.116 115.323 80.469  1.00 74.65  ? 23  TYR B CA  1 
ATOM   2887  C C   . TYR B 2 48  ? 126.309 116.545 80.889  1.00 79.07  ? 23  TYR B C   1 
ATOM   2888  O O   . TYR B 2 48  ? 126.821 117.668 80.912  1.00 79.45  ? 23  TYR B O   1 
ATOM   2889  C CB  . TYR B 2 48  ? 128.107 114.923 81.566  1.00 70.12  ? 23  TYR B CB  1 
ATOM   2890  C CG  . TYR B 2 48  ? 127.505 114.430 82.863  1.00 65.73  ? 23  TYR B CG  1 
ATOM   2891  C CD1 . TYR B 2 48  ? 126.989 115.318 83.797  1.00 63.97  ? 23  TYR B CD1 1 
ATOM   2892  C CD2 . TYR B 2 48  ? 127.473 113.075 83.163  1.00 69.63  ? 23  TYR B CD2 1 
ATOM   2893  C CE1 . TYR B 2 48  ? 126.449 114.871 84.984  1.00 65.23  ? 23  TYR B CE1 1 
ATOM   2894  C CE2 . TYR B 2 48  ? 126.934 112.619 84.350  1.00 71.17  ? 23  TYR B CE2 1 
ATOM   2895  C CZ  . TYR B 2 48  ? 126.424 113.522 85.256  1.00 67.94  ? 23  TYR B CZ  1 
ATOM   2896  O OH  . TYR B 2 48  ? 125.885 113.075 86.442  1.00 63.60  ? 23  TYR B OH  1 
ATOM   2897  N N   . ASP B 2 49  ? 125.040 116.319 81.217  1.00 82.20  ? 24  ASP B N   1 
ATOM   2898  C CA  . ASP B 2 49  ? 124.110 117.371 81.621  1.00 78.90  ? 24  ASP B CA  1 
ATOM   2899  C C   . ASP B 2 49  ? 123.789 117.159 83.097  1.00 73.11  ? 24  ASP B C   1 
ATOM   2900  O O   . ASP B 2 49  ? 122.984 116.290 83.445  1.00 69.95  ? 24  ASP B O   1 
ATOM   2901  C CB  . ASP B 2 49  ? 122.852 117.349 80.759  1.00 79.68  ? 24  ASP B CB  1 
ATOM   2902  C CG  . ASP B 2 49  ? 121.984 118.577 80.960  1.00 80.88  ? 24  ASP B CG  1 
ATOM   2903  O OD1 . ASP B 2 49  ? 122.387 119.476 81.727  1.00 77.83  ? 24  ASP B OD1 1 
ATOM   2904  O OD2 . ASP B 2 49  ? 120.897 118.644 80.349  1.00 85.93  ? 24  ASP B OD2 1 
ATOM   2905  N N   . ILE B 2 50  ? 124.420 117.955 83.965  1.00 69.71  ? 25  ILE B N   1 
ATOM   2906  C CA  . ILE B 2 50  ? 124.221 117.792 85.402  1.00 68.64  ? 25  ILE B CA  1 
ATOM   2907  C C   . ILE B 2 50  ? 122.781 118.100 85.790  1.00 70.36  ? 25  ILE B C   1 
ATOM   2908  O O   . ILE B 2 50  ? 122.250 117.531 86.752  1.00 66.76  ? 25  ILE B O   1 
ATOM   2909  C CB  . ILE B 2 50  ? 125.221 118.688 86.163  1.00 66.96  ? 25  ILE B CB  1 
ATOM   2910  C CG1 . ILE B 2 50  ? 124.827 118.841 87.634  1.00 64.78  ? 25  ILE B CG1 1 
ATOM   2911  C CG2 . ILE B 2 50  ? 125.328 120.049 85.495  1.00 64.74  ? 25  ILE B CG2 1 
ATOM   2912  C CD1 . ILE B 2 50  ? 125.809 119.657 88.446  1.00 62.76  ? 25  ILE B CD1 1 
ATOM   2913  N N   . ARG B 2 51  ? 122.119 118.982 85.040  1.00 73.36  ? 26  ARG B N   1 
ATOM   2914  C CA  . ARG B 2 51  ? 120.778 119.437 85.389  1.00 70.84  ? 26  ARG B CA  1 
ATOM   2915  C C   . ARG B 2 51  ? 119.730 118.329 85.334  1.00 71.82  ? 26  ARG B C   1 
ATOM   2916  O O   . ARG B 2 51  ? 118.663 118.479 85.938  1.00 71.78  ? 26  ARG B O   1 
ATOM   2917  C CB  . ARG B 2 51  ? 120.373 120.591 84.471  1.00 65.04  ? 26  ARG B CB  1 
ATOM   2918  C CG  . ARG B 2 51  ? 121.277 121.807 84.599  1.00 59.85  ? 26  ARG B CG  1 
ATOM   2919  C CD  . ARG B 2 51  ? 121.002 122.833 83.517  1.00 60.63  ? 26  ARG B CD  1 
ATOM   2920  N NE  . ARG B 2 51  ? 121.311 122.316 82.189  1.00 66.25  ? 26  ARG B NE  1 
ATOM   2921  C CZ  . ARG B 2 51  ? 121.232 123.026 81.073  1.00 66.77  ? 26  ARG B CZ  1 
ATOM   2922  N NH1 . ARG B 2 51  ? 120.860 124.295 81.085  1.00 66.95  ? 26  ARG B NH1 1 
ATOM   2923  N NH2 . ARG B 2 51  ? 121.536 122.448 79.914  1.00 63.82  ? 26  ARG B NH2 1 
ATOM   2924  N N   . LEU B 2 52  ? 120.001 117.230 84.636  1.00 72.82  ? 27  LEU B N   1 
ATOM   2925  C CA  . LEU B 2 52  ? 119.043 116.143 84.478  1.00 69.03  ? 27  LEU B CA  1 
ATOM   2926  C C   . LEU B 2 52  ? 119.433 114.923 85.300  1.00 71.45  ? 27  LEU B C   1 
ATOM   2927  O O   . LEU B 2 52  ? 120.597 114.512 85.311  1.00 77.16  ? 27  LEU B O   1 
ATOM   2928  C CB  . LEU B 2 52  ? 118.918 115.743 83.008  1.00 69.84  ? 27  LEU B CB  1 
ATOM   2929  C CG  . LEU B 2 52  ? 118.669 116.901 82.045  1.00 72.44  ? 27  LEU B CG  1 
ATOM   2930  C CD1 . LEU B 2 52  ? 118.450 116.390 80.631  1.00 80.38  ? 27  LEU B CD1 1 
ATOM   2931  C CD2 . LEU B 2 52  ? 117.488 117.721 82.518  1.00 76.67  ? 27  LEU B CD2 1 
ATOM   2932  N N   . ARG B 2 53  ? 118.445 114.345 85.978  1.00 70.42  ? 28  ARG B N   1 
ATOM   2933  C CA  . ARG B 2 53  ? 118.650 113.191 86.835  1.00 70.90  ? 28  ARG B CA  1 
ATOM   2934  C C   . ARG B 2 53  ? 118.839 111.930 85.995  1.00 73.77  ? 28  ARG B C   1 
ATOM   2935  O O   . ARG B 2 53  ? 118.514 111.910 84.806  1.00 77.54  ? 28  ARG B O   1 
ATOM   2936  C CB  . ARG B 2 53  ? 117.462 113.035 87.780  1.00 75.78  ? 28  ARG B CB  1 
ATOM   2937  C CG  . ARG B 2 53  ? 116.184 112.572 87.104  1.00 83.71  ? 28  ARG B CG  1 
ATOM   2938  C CD  . ARG B 2 53  ? 115.105 112.253 88.124  1.00 83.67  ? 28  ARG B CD  1 
ATOM   2939  N NE  . ARG B 2 53  ? 113.876 111.795 87.487  1.00 83.45  ? 28  ARG B NE  1 
ATOM   2940  C CZ  . ARG B 2 53  ? 113.626 110.534 87.164  1.00 84.56  ? 28  ARG B CZ  1 
ATOM   2941  N NH1 . ARG B 2 53  ? 114.508 109.575 87.390  1.00 88.14  ? 28  ARG B NH1 1 
ATOM   2942  N NH2 . ARG B 2 53  ? 112.464 110.228 86.595  1.00 80.74  ? 28  ARG B NH2 1 
ATOM   2943  N N   . PRO B 2 54  ? 119.377 110.863 86.588  1.00 75.21  ? 29  PRO B N   1 
ATOM   2944  C CA  . PRO B 2 54  ? 119.406 109.570 85.892  1.00 85.03  ? 29  PRO B CA  1 
ATOM   2945  C C   . PRO B 2 54  ? 118.013 109.092 85.514  1.00 88.78  ? 29  PRO B C   1 
ATOM   2946  O O   . PRO B 2 54  ? 117.056 109.241 86.276  1.00 87.73  ? 29  PRO B O   1 
ATOM   2947  C CB  . PRO B 2 54  ? 120.055 108.631 86.915  1.00 82.40  ? 29  PRO B CB  1 
ATOM   2948  C CG  . PRO B 2 54  ? 120.834 109.515 87.807  1.00 73.45  ? 29  PRO B CG  1 
ATOM   2949  C CD  . PRO B 2 54  ? 120.089 110.811 87.876  1.00 68.75  ? 29  PRO B CD  1 
ATOM   2950  N N   . ASP B 2 55  ? 117.913 108.507 84.319  1.00 89.22  ? 30  ASP B N   1 
ATOM   2951  C CA  . ASP B 2 55  ? 116.636 108.056 83.767  1.00 91.85  ? 30  ASP B CA  1 
ATOM   2952  C C   . ASP B 2 55  ? 115.599 109.175 83.765  1.00 88.91  ? 30  ASP B C   1 
ATOM   2953  O O   . ASP B 2 55  ? 114.432 108.966 84.101  1.00 90.21  ? 30  ASP B O   1 
ATOM   2954  C CB  . ASP B 2 55  ? 116.118 106.830 84.518  1.00 92.62  ? 30  ASP B CB  1 
ATOM   2955  C CG  . ASP B 2 55  ? 116.927 105.583 84.223  1.00 99.07  ? 30  ASP B CG  1 
ATOM   2956  O OD1 . ASP B 2 55  ? 118.040 105.713 83.670  1.00 97.07  ? 30  ASP B OD1 1 
ATOM   2957  O OD2 . ASP B 2 55  ? 116.451 104.472 84.539  1.00 101.95 ? 30  ASP B OD2 1 
ATOM   2958  N N   . PHE B 2 56  ? 116.039 110.382 83.411  1.00 84.61  ? 31  PHE B N   1 
ATOM   2959  C CA  . PHE B 2 56  ? 115.129 111.517 83.339  1.00 84.93  ? 31  PHE B CA  1 
ATOM   2960  C C   . PHE B 2 56  ? 113.965 111.198 82.408  1.00 91.33  ? 31  PHE B C   1 
ATOM   2961  O O   . PHE B 2 56  ? 114.159 110.699 81.296  1.00 94.34  ? 31  PHE B O   1 
ATOM   2962  C CB  . PHE B 2 56  ? 115.876 112.762 82.858  1.00 81.14  ? 31  PHE B CB  1 
ATOM   2963  C CG  . PHE B 2 56  ? 114.992 113.956 82.645  1.00 81.18  ? 31  PHE B CG  1 
ATOM   2964  C CD1 . PHE B 2 56  ? 114.680 114.795 83.701  1.00 84.28  ? 31  PHE B CD1 1 
ATOM   2965  C CD2 . PHE B 2 56  ? 114.481 114.245 81.392  1.00 81.55  ? 31  PHE B CD2 1 
ATOM   2966  C CE1 . PHE B 2 56  ? 113.868 115.894 83.512  1.00 83.38  ? 31  PHE B CE1 1 
ATOM   2967  C CE2 . PHE B 2 56  ? 113.668 115.343 81.198  1.00 84.29  ? 31  PHE B CE2 1 
ATOM   2968  C CZ  . PHE B 2 56  ? 113.363 116.168 82.258  1.00 82.76  ? 31  PHE B CZ  1 
ATOM   2969  N N   . GLY B 2 57  ? 112.752 111.490 82.869  1.00 92.82  ? 32  GLY B N   1 
ATOM   2970  C CA  . GLY B 2 57  ? 111.567 111.139 82.116  1.00 88.34  ? 32  GLY B CA  1 
ATOM   2971  C C   . GLY B 2 57  ? 111.281 109.657 82.081  1.00 91.81  ? 32  GLY B C   1 
ATOM   2972  O O   . GLY B 2 57  ? 110.539 109.196 81.210  1.00 99.47  ? 32  GLY B O   1 
ATOM   2973  N N   . GLY B 2 58  ? 111.851 108.894 83.011  1.00 90.15  ? 33  GLY B N   1 
ATOM   2974  C CA  . GLY B 2 58  ? 111.662 107.466 83.065  1.00 91.59  ? 33  GLY B CA  1 
ATOM   2975  C C   . GLY B 2 58  ? 111.304 107.005 84.463  1.00 93.14  ? 33  GLY B C   1 
ATOM   2976  O O   . GLY B 2 58  ? 110.749 107.762 85.266  1.00 88.03  ? 33  GLY B O   1 
ATOM   2977  N N   . PRO B 2 59  ? 111.604 105.745 84.774  1.00 97.24  ? 34  PRO B N   1 
ATOM   2978  C CA  . PRO B 2 59  ? 111.319 105.239 86.113  1.00 91.98  ? 34  PRO B CA  1 
ATOM   2979  C C   . PRO B 2 59  ? 112.085 106.028 87.155  1.00 89.04  ? 34  PRO B C   1 
ATOM   2980  O O   . PRO B 2 59  ? 113.191 106.534 86.886  1.00 92.45  ? 34  PRO B O   1 
ATOM   2981  C CB  . PRO B 2 59  ? 111.794 103.780 86.049  1.00 87.62  ? 34  PRO B CB  1 
ATOM   2982  C CG  . PRO B 2 59  ? 111.808 103.439 84.596  1.00 87.42  ? 34  PRO B CG  1 
ATOM   2983  C CD  . PRO B 2 59  ? 112.161 104.708 83.889  1.00 91.99  ? 34  PRO B CD  1 
ATOM   2984  N N   . PRO B 2 60  ? 111.529 106.177 88.356  1.00 81.49  ? 35  PRO B N   1 
ATOM   2985  C CA  . PRO B 2 60  ? 112.222 106.947 89.395  1.00 79.75  ? 35  PRO B CA  1 
ATOM   2986  C C   . PRO B 2 60  ? 113.571 106.334 89.741  1.00 82.79  ? 35  PRO B C   1 
ATOM   2987  O O   . PRO B 2 60  ? 113.724 105.113 89.796  1.00 85.96  ? 35  PRO B O   1 
ATOM   2988  C CB  . PRO B 2 60  ? 111.257 106.889 90.583  1.00 80.72  ? 35  PRO B CB  1 
ATOM   2989  C CG  . PRO B 2 60  ? 110.437 105.669 90.344  1.00 87.76  ? 35  PRO B CG  1 
ATOM   2990  C CD  . PRO B 2 60  ? 110.292 105.557 88.856  1.00 83.37  ? 35  PRO B CD  1 
ATOM   2991  N N   . VAL B 2 61  ? 114.552 107.200 89.972  1.00 86.35  ? 36  VAL B N   1 
ATOM   2992  C CA  . VAL B 2 61  ? 115.883 106.761 90.376  1.00 80.84  ? 36  VAL B CA  1 
ATOM   2993  C C   . VAL B 2 61  ? 115.856 106.370 91.849  1.00 75.24  ? 36  VAL B C   1 
ATOM   2994  O O   . VAL B 2 61  ? 115.346 107.115 92.695  1.00 72.72  ? 36  VAL B O   1 
ATOM   2995  C CB  . VAL B 2 61  ? 116.928 107.855 90.095  1.00 71.52  ? 36  VAL B CB  1 
ATOM   2996  C CG1 . VAL B 2 61  ? 116.534 109.172 90.748  1.00 69.42  ? 36  VAL B CG1 1 
ATOM   2997  C CG2 . VAL B 2 61  ? 118.304 107.412 90.562  1.00 63.11  ? 36  VAL B CG2 1 
ATOM   2998  N N   . CYS B 2 62  ? 116.382 105.188 92.157  1.00 72.91  ? 37  CYS B N   1 
ATOM   2999  C CA  . CYS B 2 62  ? 116.419 104.677 93.521  1.00 68.15  ? 37  CYS B CA  1 
ATOM   3000  C C   . CYS B 2 62  ? 117.772 105.023 94.128  1.00 59.79  ? 37  CYS B C   1 
ATOM   3001  O O   . CYS B 2 62  ? 118.812 104.611 93.604  1.00 58.18  ? 37  CYS B O   1 
ATOM   3002  C CB  . CYS B 2 62  ? 116.187 103.167 93.548  1.00 73.01  ? 37  CYS B CB  1 
ATOM   3003  S SG  . CYS B 2 62  ? 114.519 102.655 93.079  1.00 83.77  ? 37  CYS B SG  1 
ATOM   3004  N N   . VAL B 2 63  ? 117.759 105.767 95.229  1.00 53.99  ? 38  VAL B N   1 
ATOM   3005  C CA  . VAL B 2 63  ? 118.982 106.228 95.875  1.00 50.00  ? 38  VAL B CA  1 
ATOM   3006  C C   . VAL B 2 63  ? 119.119 105.498 97.201  1.00 48.52  ? 38  VAL B C   1 
ATOM   3007  O O   . VAL B 2 63  ? 118.348 105.738 98.138  1.00 45.96  ? 38  VAL B O   1 
ATOM   3008  C CB  . VAL B 2 63  ? 118.983 107.748 96.077  1.00 41.22  ? 38  VAL B CB  1 
ATOM   3009  C CG1 . VAL B 2 63  ? 120.298 108.197 96.684  1.00 42.57  ? 38  VAL B CG1 1 
ATOM   3010  C CG2 . VAL B 2 63  ? 118.746 108.452 94.758  1.00 39.02  ? 38  VAL B CG2 1 
ATOM   3011  N N   . GLY B 2 64  ? 120.105 104.609 97.285  1.00 48.64  ? 39  GLY B N   1 
ATOM   3012  C CA  . GLY B 2 64  ? 120.404 103.922 98.526  1.00 43.22  ? 39  GLY B CA  1 
ATOM   3013  C C   . GLY B 2 64  ? 121.374 104.735 99.365  1.00 39.85  ? 39  GLY B C   1 
ATOM   3014  O O   . GLY B 2 64  ? 122.304 105.347 98.846  1.00 46.74  ? 39  GLY B O   1 
ATOM   3015  N N   . MET B 2 65  ? 121.145 104.732 100.673 1.00 34.78  ? 40  MET B N   1 
ATOM   3016  C CA  . MET B 2 65  ? 121.935 105.539 101.587 1.00 32.58  ? 40  MET B CA  1 
ATOM   3017  C C   . MET B 2 65  ? 122.394 104.692 102.759 1.00 35.07  ? 40  MET B C   1 
ATOM   3018  O O   . MET B 2 65  ? 121.663 103.818 103.231 1.00 47.59  ? 40  MET B O   1 
ATOM   3019  C CB  . MET B 2 65  ? 121.142 106.742 102.101 1.00 30.48  ? 40  MET B CB  1 
ATOM   3020  C CG  . MET B 2 65  ? 120.600 107.633 101.006 1.00 30.99  ? 40  MET B CG  1 
ATOM   3021  S SD  . MET B 2 65  ? 119.843 109.130 101.650 1.00 41.52  ? 40  MET B SD  1 
ATOM   3022  C CE  . MET B 2 65  ? 119.220 109.848 100.136 1.00 41.90  ? 40  MET B CE  1 
ATOM   3023  N N   . ASN B 2 66  ? 123.610 104.958 103.222 1.00 29.76  ? 41  ASN B N   1 
ATOM   3024  C CA  . ASN B 2 66  ? 124.080 104.442 104.494 1.00 32.63  ? 41  ASN B CA  1 
ATOM   3025  C C   . ASN B 2 66  ? 124.935 105.506 105.160 1.00 33.20  ? 41  ASN B C   1 
ATOM   3026  O O   . ASN B 2 66  ? 125.513 106.371 104.499 1.00 37.78  ? 41  ASN B O   1 
ATOM   3027  C CB  . ASN B 2 66  ? 124.866 103.135 104.323 1.00 34.37  ? 41  ASN B CB  1 
ATOM   3028  C CG  . ASN B 2 66  ? 125.854 103.189 103.185 1.00 35.94  ? 41  ASN B CG  1 
ATOM   3029  O OD1 . ASN B 2 66  ? 125.562 102.740 102.081 1.00 42.84  ? 41  ASN B OD1 1 
ATOM   3030  N ND2 . ASN B 2 66  ? 127.035 103.732 103.448 1.00 29.67  ? 41  ASN B ND2 1 
ATOM   3031  N N   . ILE B 2 67  ? 125.001 105.441 106.484 1.00 30.90  ? 42  ILE B N   1 
ATOM   3032  C CA  . ILE B 2 67  ? 125.700 106.436 107.282 1.00 28.89  ? 42  ILE B CA  1 
ATOM   3033  C C   . ILE B 2 67  ? 126.664 105.736 108.227 1.00 31.60  ? 42  ILE B C   1 
ATOM   3034  O O   . ILE B 2 67  ? 126.325 104.711 108.826 1.00 37.89  ? 42  ILE B O   1 
ATOM   3035  C CB  . ILE B 2 67  ? 124.706 107.319 108.066 1.00 27.14  ? 42  ILE B CB  1 
ATOM   3036  C CG1 . ILE B 2 67  ? 123.849 108.140 107.100 1.00 27.18  ? 42  ILE B CG1 1 
ATOM   3037  C CG2 . ILE B 2 67  ? 125.430 108.216 109.054 1.00 25.93  ? 42  ILE B CG2 1 
ATOM   3038  C CD1 . ILE B 2 67  ? 122.662 108.805 107.752 1.00 34.09  ? 42  ILE B CD1 1 
ATOM   3039  N N   . ASP B 2 68  ? 127.870 106.282 108.347 1.00 27.12  ? 43  ASP B N   1 
ATOM   3040  C CA  . ASP B 2 68  ? 128.867 105.798 109.296 1.00 27.66  ? 43  ASP B CA  1 
ATOM   3041  C C   . ASP B 2 68  ? 129.129 106.940 110.265 1.00 27.86  ? 43  ASP B C   1 
ATOM   3042  O O   . ASP B 2 68  ? 129.797 107.918 109.912 1.00 32.33  ? 43  ASP B O   1 
ATOM   3043  C CB  . ASP B 2 68  ? 130.148 105.357 108.591 1.00 30.28  ? 43  ASP B CB  1 
ATOM   3044  C CG  . ASP B 2 68  ? 129.935 104.159 107.689 1.00 41.88  ? 43  ASP B CG  1 
ATOM   3045  O OD1 . ASP B 2 68  ? 129.310 103.177 108.140 1.00 42.07  ? 43  ASP B OD1 1 
ATOM   3046  O OD2 . ASP B 2 68  ? 130.395 104.198 106.529 1.00 48.25  ? 43  ASP B OD2 1 
ATOM   3047  N N   . ILE B 2 69  ? 128.604 106.821 111.476 1.00 26.28  ? 44  ILE B N   1 
ATOM   3048  C CA  . ILE B 2 69  ? 128.654 107.917 112.435 1.00 27.47  ? 44  ILE B CA  1 
ATOM   3049  C C   . ILE B 2 69  ? 130.037 107.975 113.065 1.00 32.58  ? 44  ILE B C   1 
ATOM   3050  O O   . ILE B 2 69  ? 130.539 106.973 113.586 1.00 42.22  ? 44  ILE B O   1 
ATOM   3051  C CB  . ILE B 2 69  ? 127.560 107.758 113.498 1.00 31.96  ? 44  ILE B CB  1 
ATOM   3052  C CG1 . ILE B 2 69  ? 126.180 107.874 112.848 1.00 28.81  ? 44  ILE B CG1 1 
ATOM   3053  C CG2 . ILE B 2 69  ? 127.731 108.799 114.588 1.00 33.50  ? 44  ILE B CG2 1 
ATOM   3054  C CD1 . ILE B 2 69  ? 125.042 107.521 113.770 1.00 35.83  ? 44  ILE B CD1 1 
ATOM   3055  N N   . ALA B 2 70  ? 130.660 109.151 113.015 1.00 31.21  ? 45  ALA B N   1 
ATOM   3056  C CA  . ALA B 2 70  ? 131.966 109.337 113.634 1.00 32.09  ? 45  ALA B CA  1 
ATOM   3057  C C   . ALA B 2 70  ? 131.857 109.773 115.090 1.00 33.43  ? 45  ALA B C   1 
ATOM   3058  O O   . ALA B 2 70  ? 132.632 109.304 115.930 1.00 34.35  ? 45  ALA B O   1 
ATOM   3059  C CB  . ALA B 2 70  ? 132.785 110.357 112.841 1.00 26.69  ? 45  ALA B CB  1 
ATOM   3060  N N   . SER B 2 71  ? 130.900 110.642 115.409 1.00 30.85  ? 46  SER B N   1 
ATOM   3061  C CA  . SER B 2 71  ? 130.703 111.108 116.776 1.00 33.55  ? 46  SER B CA  1 
ATOM   3062  C C   . SER B 2 71  ? 129.446 111.961 116.839 1.00 32.18  ? 46  SER B C   1 
ATOM   3063  O O   . SER B 2 71  ? 129.042 112.570 115.845 1.00 29.47  ? 46  SER B O   1 
ATOM   3064  C CB  . SER B 2 71  ? 131.902 111.920 117.280 1.00 37.49  ? 46  SER B CB  1 
ATOM   3065  O OG  . SER B 2 71  ? 132.126 113.055 116.462 1.00 38.86  ? 46  SER B OG  1 
ATOM   3066  N N   . ILE B 2 72  ? 128.839 111.991 118.021 1.00 42.44  ? 47  ILE B N   1 
ATOM   3067  C CA  . ILE B 2 72  ? 127.775 112.927 118.365 1.00 44.55  ? 47  ILE B CA  1 
ATOM   3068  C C   . ILE B 2 72  ? 128.370 113.907 119.370 1.00 45.11  ? 47  ILE B C   1 
ATOM   3069  O O   . ILE B 2 72  ? 128.444 113.615 120.568 1.00 46.23  ? 47  ILE B O   1 
ATOM   3070  C CB  . ILE B 2 72  ? 126.538 112.215 118.920 1.00 41.07  ? 47  ILE B CB  1 
ATOM   3071  C CG1 . ILE B 2 72  ? 125.915 111.333 117.838 1.00 37.37  ? 47  ILE B CG1 1 
ATOM   3072  C CG2 . ILE B 2 72  ? 125.516 113.222 119.414 1.00 38.62  ? 47  ILE B CG2 1 
ATOM   3073  C CD1 . ILE B 2 72  ? 124.772 110.481 118.322 1.00 44.12  ? 47  ILE B CD1 1 
ATOM   3074  N N   . ASP B 2 73  ? 128.825 115.064 118.884 1.00 42.29  ? 48  ASP B N   1 
ATOM   3075  C CA  . ASP B 2 73  ? 129.686 115.918 119.698 1.00 45.43  ? 48  ASP B CA  1 
ATOM   3076  C C   . ASP B 2 73  ? 128.939 116.496 120.894 1.00 47.75  ? 48  ASP B C   1 
ATOM   3077  O O   . ASP B 2 73  ? 129.403 116.392 122.035 1.00 54.49  ? 48  ASP B O   1 
ATOM   3078  C CB  . ASP B 2 73  ? 130.266 117.040 118.838 1.00 47.08  ? 48  ASP B CB  1 
ATOM   3079  C CG  . ASP B 2 73  ? 130.901 116.528 117.561 1.00 47.85  ? 48  ASP B CG  1 
ATOM   3080  O OD1 . ASP B 2 73  ? 131.586 115.485 117.611 1.00 49.69  ? 48  ASP B OD1 1 
ATOM   3081  O OD2 . ASP B 2 73  ? 130.712 117.167 116.505 1.00 45.08  ? 48  ASP B OD2 1 
ATOM   3082  N N   . MET B 2 74  ? 127.778 117.106 120.659 1.00 43.01  ? 49  MET B N   1 
ATOM   3083  C CA  . MET B 2 74  ? 127.081 117.844 121.702 1.00 43.77  ? 49  MET B CA  1 
ATOM   3084  C C   . MET B 2 74  ? 125.587 117.577 121.615 1.00 46.89  ? 49  MET B C   1 
ATOM   3085  O O   . MET B 2 74  ? 125.046 117.334 120.534 1.00 52.95  ? 49  MET B O   1 
ATOM   3086  C CB  . MET B 2 74  ? 127.337 119.358 121.609 1.00 44.40  ? 49  MET B CB  1 
ATOM   3087  C CG  . MET B 2 74  ? 128.804 119.759 121.666 1.00 48.97  ? 49  MET B CG  1 
ATOM   3088  S SD  . MET B 2 74  ? 129.053 121.533 121.470 1.00 86.96  ? 49  MET B SD  1 
ATOM   3089  C CE  . MET B 2 74  ? 128.330 122.141 122.991 1.00 69.53  ? 49  MET B CE  1 
ATOM   3090  N N   . VAL B 2 75  ? 124.927 117.624 122.772 1.00 45.75  ? 50  VAL B N   1 
ATOM   3091  C CA  . VAL B 2 75  ? 123.471 117.563 122.865 1.00 44.05  ? 50  VAL B CA  1 
ATOM   3092  C C   . VAL B 2 75  ? 123.027 118.621 123.866 1.00 54.81  ? 50  VAL B C   1 
ATOM   3093  O O   . VAL B 2 75  ? 123.169 118.436 125.080 1.00 59.00  ? 50  VAL B O   1 
ATOM   3094  C CB  . VAL B 2 75  ? 122.975 116.166 123.287 1.00 39.19  ? 50  VAL B CB  1 
ATOM   3095  C CG1 . VAL B 2 75  ? 121.468 116.080 123.149 1.00 43.10  ? 50  VAL B CG1 1 
ATOM   3096  C CG2 . VAL B 2 75  ? 123.642 115.073 122.468 1.00 36.92  ? 50  VAL B CG2 1 
ATOM   3097  N N   . SER B 2 76  ? 122.484 119.731 123.373 1.00 55.46  ? 51  SER B N   1 
ATOM   3098  C CA  . SER B 2 76  ? 122.159 120.882 124.208 1.00 54.39  ? 51  SER B CA  1 
ATOM   3099  C C   . SER B 2 76  ? 120.651 120.992 124.381 1.00 54.43  ? 51  SER B C   1 
ATOM   3100  O O   . SER B 2 76  ? 119.913 121.092 123.395 1.00 56.90  ? 51  SER B O   1 
ATOM   3101  C CB  . SER B 2 76  ? 122.719 122.167 123.600 1.00 56.58  ? 51  SER B CB  1 
ATOM   3102  O OG  . SER B 2 76  ? 122.071 122.475 122.379 1.00 62.26  ? 51  SER B OG  1 
ATOM   3103  N N   . GLU B 2 77  ? 120.202 120.972 125.638 1.00 56.98  ? 52  GLU B N   1 
ATOM   3104  C CA  . GLU B 2 77  ? 118.788 121.160 125.944 1.00 59.27  ? 52  GLU B CA  1 
ATOM   3105  C C   . GLU B 2 77  ? 118.338 122.599 125.717 1.00 63.20  ? 52  GLU B C   1 
ATOM   3106  O O   . GLU B 2 77  ? 117.183 122.833 125.345 1.00 64.14  ? 52  GLU B O   1 
ATOM   3107  C CB  . GLU B 2 77  ? 118.500 120.738 127.385 1.00 55.68  ? 52  GLU B CB  1 
ATOM   3108  C CG  . GLU B 2 77  ? 118.775 119.270 127.695 1.00 51.30  ? 52  GLU B CG  1 
ATOM   3109  C CD  . GLU B 2 77  ? 120.239 118.980 127.966 1.00 51.30  ? 52  GLU B CD  1 
ATOM   3110  O OE1 . GLU B 2 77  ? 121.084 119.862 127.710 1.00 53.06  ? 52  GLU B OE1 1 
ATOM   3111  O OE2 . GLU B 2 77  ? 120.545 117.866 128.440 1.00 45.70  ? 52  GLU B OE2 1 
ATOM   3112  N N   . VAL B 2 78  ? 119.225 123.570 125.947 1.00 67.57  ? 53  VAL B N   1 
ATOM   3113  C CA  . VAL B 2 78  ? 118.857 124.981 125.827 1.00 68.56  ? 53  VAL B CA  1 
ATOM   3114  C C   . VAL B 2 78  ? 118.486 125.314 124.388 1.00 63.55  ? 53  VAL B C   1 
ATOM   3115  O O   . VAL B 2 78  ? 117.438 125.913 124.118 1.00 62.07  ? 53  VAL B O   1 
ATOM   3116  C CB  . VAL B 2 78  ? 119.997 125.881 126.333 1.00 67.16  ? 53  VAL B CB  1 
ATOM   3117  C CG1 . VAL B 2 78  ? 119.496 127.301 126.538 1.00 63.51  ? 53  VAL B CG1 1 
ATOM   3118  C CG2 . VAL B 2 78  ? 120.581 125.325 127.621 1.00 66.32  ? 53  VAL B CG2 1 
ATOM   3119  N N   . ASN B 2 79  ? 119.343 124.934 123.446 1.00 60.53  ? 54  ASN B N   1 
ATOM   3120  C CA  . ASN B 2 79  ? 119.111 125.175 122.030 1.00 62.41  ? 54  ASN B CA  1 
ATOM   3121  C C   . ASN B 2 79  ? 118.190 124.140 121.403 1.00 60.72  ? 54  ASN B C   1 
ATOM   3122  O O   . ASN B 2 79  ? 117.737 124.347 120.273 1.00 54.92  ? 54  ASN B O   1 
ATOM   3123  C CB  . ASN B 2 79  ? 120.440 125.204 121.272 1.00 61.74  ? 54  ASN B CB  1 
ATOM   3124  C CG  . ASN B 2 79  ? 121.433 126.176 121.873 1.00 70.25  ? 54  ASN B CG  1 
ATOM   3125  O OD1 . ASN B 2 79  ? 121.138 126.852 122.858 1.00 79.36  ? 54  ASN B OD1 1 
ATOM   3126  N ND2 . ASN B 2 79  ? 122.618 126.252 121.282 1.00 71.40  ? 54  ASN B ND2 1 
ATOM   3127  N N   . MET B 2 80  ? 117.902 123.049 122.111 1.00 61.25  ? 55  MET B N   1 
ATOM   3128  C CA  . MET B 2 80  ? 117.071 121.957 121.614 1.00 56.84  ? 55  MET B CA  1 
ATOM   3129  C C   . MET B 2 80  ? 117.617 121.448 120.282 1.00 54.14  ? 55  MET B C   1 
ATOM   3130  O O   . MET B 2 80  ? 116.965 121.505 119.239 1.00 56.36  ? 55  MET B O   1 
ATOM   3131  C CB  . MET B 2 80  ? 115.618 122.417 121.459 1.00 59.44  ? 55  MET B CB  1 
ATOM   3132  C CG  . MET B 2 80  ? 114.795 122.445 122.732 1.00 63.13  ? 55  MET B CG  1 
ATOM   3133  S SD  . MET B 2 80  ? 114.337 120.824 123.351 1.00 72.29  ? 55  MET B SD  1 
ATOM   3134  C CE  . MET B 2 80  ? 113.610 121.280 124.920 1.00 61.20  ? 55  MET B CE  1 
ATOM   3135  N N   . ASP B 2 81  ? 118.843 120.937 120.347 1.00 50.21  ? 56  ASP B N   1 
ATOM   3136  C CA  . ASP B 2 81  ? 119.517 120.394 119.177 1.00 47.84  ? 56  ASP B CA  1 
ATOM   3137  C C   . ASP B 2 81  ? 120.694 119.539 119.625 1.00 47.42  ? 56  ASP B C   1 
ATOM   3138  O O   . ASP B 2 81  ? 121.119 119.583 120.782 1.00 48.66  ? 56  ASP B O   1 
ATOM   3139  C CB  . ASP B 2 81  ? 119.961 121.514 118.227 1.00 47.74  ? 56  ASP B CB  1 
ATOM   3140  C CG  . ASP B 2 81  ? 120.914 122.510 118.877 1.00 53.33  ? 56  ASP B CG  1 
ATOM   3141  O OD1 . ASP B 2 81  ? 121.423 122.252 119.986 1.00 59.20  ? 56  ASP B OD1 1 
ATOM   3142  O OD2 . ASP B 2 81  ? 121.148 123.576 118.271 1.00 57.85  ? 56  ASP B OD2 1 
ATOM   3143  N N   . TYR B 2 82  ? 121.208 118.747 118.689 1.00 41.54  ? 57  TYR B N   1 
ATOM   3144  C CA  . TYR B 2 82  ? 122.390 117.933 118.918 1.00 37.30  ? 57  TYR B CA  1 
ATOM   3145  C C   . TYR B 2 82  ? 123.306 118.080 117.712 1.00 36.03  ? 57  TYR B C   1 
ATOM   3146  O O   . TYR B 2 82  ? 122.865 118.417 116.612 1.00 39.11  ? 57  TYR B O   1 
ATOM   3147  C CB  . TYR B 2 82  ? 122.047 116.455 119.172 1.00 32.35  ? 57  TYR B CB  1 
ATOM   3148  C CG  . TYR B 2 82  ? 121.369 115.740 118.027 1.00 27.88  ? 57  TYR B CG  1 
ATOM   3149  C CD1 . TYR B 2 82  ? 120.035 115.970 117.729 1.00 34.32  ? 57  TYR B CD1 1 
ATOM   3150  C CD2 . TYR B 2 82  ? 122.062 114.820 117.255 1.00 26.58  ? 57  TYR B CD2 1 
ATOM   3151  C CE1 . TYR B 2 82  ? 119.414 115.313 116.688 1.00 37.37  ? 57  TYR B CE1 1 
ATOM   3152  C CE2 . TYR B 2 82  ? 121.450 114.158 116.213 1.00 31.07  ? 57  TYR B CE2 1 
ATOM   3153  C CZ  . TYR B 2 82  ? 120.126 114.409 115.934 1.00 35.32  ? 57  TYR B CZ  1 
ATOM   3154  O OH  . TYR B 2 82  ? 119.513 113.750 114.895 1.00 35.57  ? 57  TYR B OH  1 
ATOM   3155  N N   . THR B 2 83  ? 124.591 117.819 117.927 1.00 34.79  ? 58  THR B N   1 
ATOM   3156  C CA  . THR B 2 83  ? 125.598 117.901 116.878 1.00 29.54  ? 58  THR B CA  1 
ATOM   3157  C C   . THR B 2 83  ? 126.059 116.503 116.496 1.00 31.14  ? 58  THR B C   1 
ATOM   3158  O O   . THR B 2 83  ? 126.384 115.692 117.368 1.00 35.37  ? 58  THR B O   1 
ATOM   3159  C CB  . THR B 2 83  ? 126.793 118.742 117.332 1.00 34.12  ? 58  THR B CB  1 
ATOM   3160  O OG1 . THR B 2 83  ? 126.335 120.021 117.785 1.00 33.36  ? 58  THR B OG1 1 
ATOM   3161  C CG2 . THR B 2 83  ? 127.769 118.942 116.186 1.00 33.38  ? 58  THR B CG2 1 
ATOM   3162  N N   . LEU B 2 84  ? 126.092 116.231 115.194 1.00 28.52  ? 59  LEU B N   1 
ATOM   3163  C CA  . LEU B 2 84  ? 126.392 114.903 114.676 1.00 28.04  ? 59  LEU B CA  1 
ATOM   3164  C C   . LEU B 2 84  ? 127.423 115.022 113.567 1.00 28.09  ? 59  LEU B C   1 
ATOM   3165  O O   . LEU B 2 84  ? 127.205 115.746 112.591 1.00 29.68  ? 59  LEU B O   1 
ATOM   3166  C CB  . LEU B 2 84  ? 125.118 114.235 114.150 1.00 25.91  ? 59  LEU B CB  1 
ATOM   3167  C CG  . LEU B 2 84  ? 125.240 112.930 113.366 1.00 25.32  ? 59  LEU B CG  1 
ATOM   3168  C CD1 . LEU B 2 84  ? 125.777 111.828 114.248 1.00 33.21  ? 59  LEU B CD1 1 
ATOM   3169  C CD2 . LEU B 2 84  ? 123.898 112.540 112.775 1.00 24.26  ? 59  LEU B CD2 1 
ATOM   3170  N N   . THR B 2 85  ? 128.534 114.306 113.710 1.00 27.46  ? 60  THR B N   1 
ATOM   3171  C CA  . THR B 2 85  ? 129.510 114.152 112.643 1.00 21.10  ? 60  THR B CA  1 
ATOM   3172  C C   . THR B 2 85  ? 129.374 112.756 112.058 1.00 20.93  ? 60  THR B C   1 
ATOM   3173  O O   . THR B 2 85  ? 129.239 111.777 112.797 1.00 29.59  ? 60  THR B O   1 
ATOM   3174  C CB  . THR B 2 85  ? 130.935 114.371 113.155 1.00 23.45  ? 60  THR B CB  1 
ATOM   3175  O OG1 . THR B 2 85  ? 131.026 115.655 113.783 1.00 27.61  ? 60  THR B OG1 1 
ATOM   3176  C CG2 . THR B 2 85  ? 131.926 114.311 112.007 1.00 21.72  ? 60  THR B CG2 1 
ATOM   3177  N N   . MET B 2 86  ? 129.412 112.661 110.734 1.00 17.31  ? 61  MET B N   1 
ATOM   3178  C CA  . MET B 2 86  ? 129.124 111.385 110.101 1.00 18.76  ? 61  MET B CA  1 
ATOM   3179  C C   . MET B 2 86  ? 129.751 111.341 108.719 1.00 17.34  ? 61  MET B C   1 
ATOM   3180  O O   . MET B 2 86  ? 130.161 112.362 108.164 1.00 21.69  ? 61  MET B O   1 
ATOM   3181  C CB  . MET B 2 86  ? 127.617 111.140 109.998 1.00 22.53  ? 61  MET B CB  1 
ATOM   3182  C CG  . MET B 2 86  ? 126.901 112.134 109.107 1.00 22.05  ? 61  MET B CG  1 
ATOM   3183  S SD  . MET B 2 86  ? 125.135 111.818 108.995 1.00 44.62  ? 61  MET B SD  1 
ATOM   3184  C CE  . MET B 2 86  ? 124.637 113.140 107.902 1.00 22.01  ? 61  MET B CE  1 
ATOM   3185  N N   . TYR B 2 87  ? 129.816 110.132 108.177 1.00 16.54  ? 62  TYR B N   1 
ATOM   3186  C CA  . TYR B 2 87  ? 130.167 109.893 106.784 1.00 18.17  ? 62  TYR B CA  1 
ATOM   3187  C C   . TYR B 2 87  ? 128.868 109.515 106.087 1.00 19.81  ? 62  TYR B C   1 
ATOM   3188  O O   . TYR B 2 87  ? 128.276 108.474 106.387 1.00 25.40  ? 62  TYR B O   1 
ATOM   3189  C CB  . TYR B 2 87  ? 131.221 108.798 106.641 1.00 21.31  ? 62  TYR B CB  1 
ATOM   3190  C CG  . TYR B 2 87  ? 132.506 109.062 107.395 1.00 24.61  ? 62  TYR B CG  1 
ATOM   3191  C CD1 . TYR B 2 87  ? 132.603 108.806 108.754 1.00 29.14  ? 62  TYR B CD1 1 
ATOM   3192  C CD2 . TYR B 2 87  ? 133.627 109.551 106.739 1.00 19.78  ? 62  TYR B CD2 1 
ATOM   3193  C CE1 . TYR B 2 87  ? 133.774 109.044 109.443 1.00 29.12  ? 62  TYR B CE1 1 
ATOM   3194  C CE2 . TYR B 2 87  ? 134.804 109.789 107.420 1.00 23.37  ? 62  TYR B CE2 1 
ATOM   3195  C CZ  . TYR B 2 87  ? 134.871 109.534 108.772 1.00 29.90  ? 62  TYR B CZ  1 
ATOM   3196  O OH  . TYR B 2 87  ? 136.039 109.767 109.458 1.00 36.62  ? 62  TYR B OH  1 
ATOM   3197  N N   . PHE B 2 88  ? 128.437 110.353 105.155 1.00 17.46  ? 63  PHE B N   1 
ATOM   3198  C CA  . PHE B 2 88  ? 127.119 110.253 104.541 1.00 19.44  ? 63  PHE B CA  1 
ATOM   3199  C C   . PHE B 2 88  ? 127.305 109.778 103.110 1.00 19.63  ? 63  PHE B C   1 
ATOM   3200  O O   . PHE B 2 88  ? 127.764 110.539 102.252 1.00 22.82  ? 63  PHE B O   1 
ATOM   3201  C CB  . PHE B 2 88  ? 126.400 111.599 104.592 1.00 22.29  ? 63  PHE B CB  1 
ATOM   3202  C CG  . PHE B 2 88  ? 125.051 111.593 103.939 1.00 26.54  ? 63  PHE B CG  1 
ATOM   3203  C CD1 . PHE B 2 88  ? 123.991 110.918 104.516 1.00 25.51  ? 63  PHE B CD1 1 
ATOM   3204  C CD2 . PHE B 2 88  ? 124.840 112.269 102.752 1.00 22.75  ? 63  PHE B CD2 1 
ATOM   3205  C CE1 . PHE B 2 88  ? 122.751 110.914 103.920 1.00 20.46  ? 63  PHE B CE1 1 
ATOM   3206  C CE2 . PHE B 2 88  ? 123.602 112.267 102.151 1.00 23.95  ? 63  PHE B CE2 1 
ATOM   3207  C CZ  . PHE B 2 88  ? 122.556 111.589 102.736 1.00 21.13  ? 63  PHE B CZ  1 
ATOM   3208  N N   . GLN B 2 89  ? 126.938 108.528 102.856 1.00 19.12  ? 64  GLN B N   1 
ATOM   3209  C CA  . GLN B 2 89  ? 127.098 107.912 101.549 1.00 22.46  ? 64  GLN B CA  1 
ATOM   3210  C C   . GLN B 2 89  ? 125.759 107.865 100.830 1.00 23.14  ? 64  GLN B C   1 
ATOM   3211  O O   . GLN B 2 89  ? 124.711 107.686 101.456 1.00 26.40  ? 64  GLN B O   1 
ATOM   3212  C CB  . GLN B 2 89  ? 127.661 106.496 101.685 1.00 26.81  ? 64  GLN B CB  1 
ATOM   3213  C CG  . GLN B 2 89  ? 129.173 106.416 101.831 1.00 27.82  ? 64  GLN B CG  1 
ATOM   3214  C CD  . GLN B 2 89  ? 129.649 106.803 103.217 1.00 26.78  ? 64  GLN B CD  1 
ATOM   3215  O OE1 . GLN B 2 89  ? 129.132 106.319 104.222 1.00 25.43  ? 64  GLN B OE1 1 
ATOM   3216  N NE2 . GLN B 2 89  ? 130.650 107.672 103.276 1.00 31.38  ? 64  GLN B NE2 1 
ATOM   3217  N N   . GLN B 2 90  ? 125.800 108.036 99.512  1.00 24.81  ? 65  GLN B N   1 
ATOM   3218  C CA  . GLN B 2 90  ? 124.628 107.900 98.660  1.00 26.82  ? 65  GLN B CA  1 
ATOM   3219  C C   . GLN B 2 90  ? 124.989 107.041 97.461  1.00 30.73  ? 65  GLN B C   1 
ATOM   3220  O O   . GLN B 2 90  ? 126.042 107.240 96.848  1.00 42.23  ? 65  GLN B O   1 
ATOM   3221  C CB  . GLN B 2 90  ? 124.126 109.265 98.180  1.00 25.44  ? 65  GLN B CB  1 
ATOM   3222  C CG  . GLN B 2 90  ? 123.778 110.238 99.284  1.00 28.68  ? 65  GLN B CG  1 
ATOM   3223  C CD  . GLN B 2 90  ? 123.146 111.508 98.754  1.00 38.15  ? 65  GLN B CD  1 
ATOM   3224  O OE1 . GLN B 2 90  ? 121.952 111.548 98.463  1.00 41.03  ? 65  GLN B OE1 1 
ATOM   3225  N NE2 . GLN B 2 90  ? 123.948 112.558 98.630  1.00 35.62  ? 65  GLN B NE2 1 
ATOM   3226  N N   . TYR B 2 91  ? 124.121 106.093 97.128  1.00 26.72  ? 66  TYR B N   1 
ATOM   3227  C CA  . TYR B 2 91  ? 124.355 105.172 96.027  1.00 30.00  ? 66  TYR B CA  1 
ATOM   3228  C C   . TYR B 2 91  ? 123.203 105.261 95.042  1.00 32.76  ? 66  TYR B C   1 
ATOM   3229  O O   . TYR B 2 91  ? 122.036 105.183 95.435  1.00 42.28  ? 66  TYR B O   1 
ATOM   3230  C CB  . TYR B 2 91  ? 124.516 103.735 96.525  1.00 36.92  ? 66  TYR B CB  1 
ATOM   3231  C CG  . TYR B 2 91  ? 125.703 103.517 97.434  1.00 38.99  ? 66  TYR B CG  1 
ATOM   3232  C CD1 . TYR B 2 91  ? 125.690 103.951 98.752  1.00 38.51  ? 66  TYR B CD1 1 
ATOM   3233  C CD2 . TYR B 2 91  ? 126.828 102.843 96.980  1.00 37.41  ? 66  TYR B CD2 1 
ATOM   3234  C CE1 . TYR B 2 91  ? 126.772 103.744 99.578  1.00 37.96  ? 66  TYR B CE1 1 
ATOM   3235  C CE2 . TYR B 2 91  ? 127.912 102.627 97.802  1.00 41.94  ? 66  TYR B CE2 1 
ATOM   3236  C CZ  . TYR B 2 91  ? 127.876 103.075 99.102  1.00 41.27  ? 66  TYR B CZ  1 
ATOM   3237  O OH  . TYR B 2 91  ? 128.956 102.867 99.927  1.00 40.40  ? 66  TYR B OH  1 
ATOM   3238  N N   . TRP B 2 92  ? 123.537 105.416 93.766  1.00 31.61  ? 67  TRP B N   1 
ATOM   3239  C CA  . TRP B 2 92  ? 122.555 105.369 92.697  1.00 37.34  ? 67  TRP B CA  1 
ATOM   3240  C C   . TRP B 2 92  ? 123.257 104.929 91.424  1.00 41.27  ? 67  TRP B C   1 
ATOM   3241  O O   . TRP B 2 92  ? 124.482 105.012 91.310  1.00 44.69  ? 67  TRP B O   1 
ATOM   3242  C CB  . TRP B 2 92  ? 121.866 106.722 92.487  1.00 43.49  ? 67  TRP B CB  1 
ATOM   3243  C CG  . TRP B 2 92  ? 122.783 107.798 92.001  1.00 43.21  ? 67  TRP B CG  1 
ATOM   3244  C CD1 . TRP B 2 92  ? 122.979 108.181 90.708  1.00 46.13  ? 67  TRP B CD1 1 
ATOM   3245  C CD2 . TRP B 2 92  ? 123.601 108.658 92.803  1.00 40.64  ? 67  TRP B CD2 1 
ATOM   3246  N NE1 . TRP B 2 92  ? 123.885 109.210 90.652  1.00 41.40  ? 67  TRP B NE1 1 
ATOM   3247  C CE2 . TRP B 2 92  ? 124.279 109.523 91.925  1.00 40.25  ? 67  TRP B CE2 1 
ATOM   3248  C CE3 . TRP B 2 92  ? 123.832 108.774 94.175  1.00 35.58  ? 67  TRP B CE3 1 
ATOM   3249  C CZ2 . TRP B 2 92  ? 125.172 110.490 92.375  1.00 36.65  ? 67  TRP B CZ2 1 
ATOM   3250  C CZ3 . TRP B 2 92  ? 124.718 109.734 94.618  1.00 33.40  ? 67  TRP B CZ3 1 
ATOM   3251  C CH2 . TRP B 2 92  ? 125.375 110.579 93.722  1.00 33.76  ? 67  TRP B CH2 1 
ATOM   3252  N N   . ARG B 2 93  ? 122.471 104.462 90.463  1.00 50.26  ? 68  ARG B N   1 
ATOM   3253  C CA  . ARG B 2 93  ? 123.010 103.983 89.200  1.00 62.01  ? 68  ARG B CA  1 
ATOM   3254  C C   . ARG B 2 93  ? 122.778 105.047 88.137  1.00 66.91  ? 68  ARG B C   1 
ATOM   3255  O O   . ARG B 2 93  ? 121.659 105.548 87.986  1.00 68.30  ? 68  ARG B O   1 
ATOM   3256  C CB  . ARG B 2 93  ? 122.365 102.661 88.784  1.00 64.98  ? 68  ARG B CB  1 
ATOM   3257  C CG  . ARG B 2 93  ? 123.091 101.967 87.645  1.00 69.90  ? 68  ARG B CG  1 
ATOM   3258  C CD  . ARG B 2 93  ? 122.602 100.546 87.437  1.00 80.72  ? 68  ARG B CD  1 
ATOM   3259  N NE  . ARG B 2 93  ? 123.493 99.801  86.556  1.00 98.66  ? 68  ARG B NE  1 
ATOM   3260  C CZ  . ARG B 2 93  ? 123.358 99.729  85.239  1.00 102.14 ? 68  ARG B CZ  1 
ATOM   3261  N NH1 . ARG B 2 93  ? 122.377 100.354 84.609  1.00 95.69  ? 68  ARG B NH1 1 
ATOM   3262  N NH2 . ARG B 2 93  ? 124.236 99.020  84.534  1.00 97.63  ? 68  ARG B NH2 1 
ATOM   3263  N N   . ASP B 2 94  ? 123.836 105.385 87.405  1.00 66.32  ? 69  ASP B N   1 
ATOM   3264  C CA  . ASP B 2 94  ? 123.772 106.349 86.313  1.00 69.38  ? 69  ASP B CA  1 
ATOM   3265  C C   . ASP B 2 94  ? 124.407 105.712 85.087  1.00 73.53  ? 69  ASP B C   1 
ATOM   3266  O O   . ASP B 2 94  ? 125.634 105.589 85.014  1.00 74.25  ? 69  ASP B O   1 
ATOM   3267  C CB  . ASP B 2 94  ? 124.475 107.655 86.685  1.00 66.85  ? 69  ASP B CB  1 
ATOM   3268  C CG  . ASP B 2 94  ? 124.072 108.809 85.791  1.00 68.08  ? 69  ASP B CG  1 
ATOM   3269  O OD1 . ASP B 2 94  ? 123.319 108.580 84.821  1.00 69.39  ? 69  ASP B OD1 1 
ATOM   3270  O OD2 . ASP B 2 94  ? 124.504 109.949 86.061  1.00 63.74  ? 69  ASP B OD2 1 
ATOM   3271  N N   . LYS B 2 95  ? 123.575 105.308 84.125  1.00 75.69  ? 70  LYS B N   1 
ATOM   3272  C CA  . LYS B 2 95  ? 124.092 104.647 82.933  1.00 81.76  ? 70  LYS B CA  1 
ATOM   3273  C C   . LYS B 2 95  ? 124.988 105.563 82.112  1.00 77.00  ? 70  LYS B C   1 
ATOM   3274  O O   . LYS B 2 95  ? 125.815 105.070 81.337  1.00 75.14  ? 70  LYS B O   1 
ATOM   3275  C CB  . LYS B 2 95  ? 122.932 104.149 82.072  1.00 81.18  ? 70  LYS B CB  1 
ATOM   3276  C CG  . LYS B 2 95  ? 122.085 103.077 82.732  1.00 83.08  ? 70  LYS B CG  1 
ATOM   3277  C CD  . LYS B 2 95  ? 120.789 102.864 81.971  1.00 86.65  ? 70  LYS B CD  1 
ATOM   3278  C CE  . LYS B 2 95  ? 119.914 101.825 82.649  1.00 97.40  ? 70  LYS B CE  1 
ATOM   3279  N NZ  . LYS B 2 95  ? 118.564 101.751 82.024  1.00 84.47  ? 70  LYS B NZ  1 
ATOM   3280  N N   . ARG B 2 96  ? 124.838 106.881 82.256  1.00 72.20  ? 71  ARG B N   1 
ATOM   3281  C CA  . ARG B 2 96  ? 125.748 107.810 81.601  1.00 69.61  ? 71  ARG B CA  1 
ATOM   3282  C C   . ARG B 2 96  ? 127.174 107.683 82.122  1.00 70.43  ? 71  ARG B C   1 
ATOM   3283  O O   . ARG B 2 96  ? 128.106 108.150 81.459  1.00 75.79  ? 71  ARG B O   1 
ATOM   3284  C CB  . ARG B 2 96  ? 125.251 109.243 81.785  1.00 69.48  ? 71  ARG B CB  1 
ATOM   3285  C CG  . ARG B 2 96  ? 123.892 109.510 81.164  1.00 70.26  ? 71  ARG B CG  1 
ATOM   3286  C CD  . ARG B 2 96  ? 123.402 110.907 81.502  1.00 71.53  ? 71  ARG B CD  1 
ATOM   3287  N NE  . ARG B 2 96  ? 123.294 111.106 82.942  1.00 74.74  ? 71  ARG B NE  1 
ATOM   3288  C CZ  . ARG B 2 96  ? 122.947 112.249 83.517  1.00 72.06  ? 71  ARG B CZ  1 
ATOM   3289  N NH1 . ARG B 2 96  ? 122.653 113.322 82.801  1.00 68.91  ? 71  ARG B NH1 1 
ATOM   3290  N NH2 . ARG B 2 96  ? 122.883 112.315 84.844  1.00 66.47  ? 71  ARG B NH2 1 
ATOM   3291  N N   . LEU B 2 97  ? 127.367 107.061 83.286  1.00 66.25  ? 72  LEU B N   1 
ATOM   3292  C CA  . LEU B 2 97  ? 128.687 106.909 83.883  1.00 69.04  ? 72  LEU B CA  1 
ATOM   3293  C C   . LEU B 2 97  ? 129.178 105.467 83.871  1.00 74.35  ? 72  LEU B C   1 
ATOM   3294  O O   . LEU B 2 97  ? 130.134 105.143 84.584  1.00 77.05  ? 72  LEU B O   1 
ATOM   3295  C CB  . LEU B 2 97  ? 128.690 107.448 85.315  1.00 61.15  ? 72  LEU B CB  1 
ATOM   3296  C CG  . LEU B 2 97  ? 128.435 108.947 85.479  1.00 60.53  ? 72  LEU B CG  1 
ATOM   3297  C CD1 . LEU B 2 97  ? 128.295 109.308 86.948  1.00 53.70  ? 72  LEU B CD1 1 
ATOM   3298  C CD2 . LEU B 2 97  ? 129.544 109.756 84.830  1.00 68.12  ? 72  LEU B CD2 1 
ATOM   3299  N N   . ALA B 2 98  ? 128.545 104.592 83.096  1.00 74.80  ? 73  ALA B N   1 
ATOM   3300  C CA  . ALA B 2 98  ? 129.030 103.226 82.973  1.00 74.86  ? 73  ALA B CA  1 
ATOM   3301  C C   . ALA B 2 98  ? 130.291 103.188 82.118  1.00 78.48  ? 73  ALA B C   1 
ATOM   3302  O O   . ALA B 2 98  ? 130.389 103.873 81.097  1.00 70.83  ? 73  ALA B O   1 
ATOM   3303  C CB  . ALA B 2 98  ? 127.952 102.330 82.365  1.00 70.39  ? 73  ALA B CB  1 
ATOM   3304  N N   . TYR B 2 99  ? 131.262 102.381 82.542  1.00 79.87  ? 74  TYR B N   1 
ATOM   3305  C CA  . TYR B 2 99  ? 132.501 102.220 81.798  1.00 79.79  ? 74  TYR B CA  1 
ATOM   3306  C C   . TYR B 2 99  ? 132.946 100.767 81.846  1.00 82.38  ? 74  TYR B C   1 
ATOM   3307  O O   . TYR B 2 99  ? 132.699 100.057 82.824  1.00 78.84  ? 74  TYR B O   1 
ATOM   3308  C CB  . TYR B 2 99  ? 133.612 103.131 82.344  1.00 77.90  ? 74  TYR B CB  1 
ATOM   3309  C CG  . TYR B 2 99  ? 133.994 102.862 83.784  1.00 76.66  ? 74  TYR B CG  1 
ATOM   3310  C CD1 . TYR B 2 99  ? 134.988 101.946 84.103  1.00 75.41  ? 74  TYR B CD1 1 
ATOM   3311  C CD2 . TYR B 2 99  ? 133.373 103.541 84.823  1.00 71.16  ? 74  TYR B CD2 1 
ATOM   3312  C CE1 . TYR B 2 99  ? 135.341 101.704 85.417  1.00 70.50  ? 74  TYR B CE1 1 
ATOM   3313  C CE2 . TYR B 2 99  ? 133.722 103.306 86.139  1.00 64.41  ? 74  TYR B CE2 1 
ATOM   3314  C CZ  . TYR B 2 99  ? 134.706 102.388 86.430  1.00 63.24  ? 74  TYR B CZ  1 
ATOM   3315  O OH  . TYR B 2 99  ? 135.054 102.152 87.739  1.00 58.95  ? 74  TYR B OH  1 
ATOM   3316  N N   . SER B 2 100 ? 133.613 100.336 80.779  1.00 90.09  ? 75  SER B N   1 
ATOM   3317  C CA  . SER B 2 100 ? 134.036 98.954  80.622  1.00 94.51  ? 75  SER B CA  1 
ATOM   3318  C C   . SER B 2 100 ? 135.493 98.912  80.183  1.00 98.73  ? 75  SER B C   1 
ATOM   3319  O O   . SER B 2 100 ? 136.030 99.882  79.642  1.00 97.01  ? 75  SER B O   1 
ATOM   3320  C CB  . SER B 2 100 ? 133.161 98.209  79.605  1.00 99.09  ? 75  SER B CB  1 
ATOM   3321  O OG  . SER B 2 100 ? 133.264 98.796  78.320  1.00 104.62 ? 75  SER B OG  1 
ATOM   3322  N N   . GLY B 2 101 ? 136.130 97.767  80.422  1.00 100.46 ? 76  GLY B N   1 
ATOM   3323  C CA  . GLY B 2 101 ? 137.524 97.578  80.089  1.00 98.29  ? 76  GLY B CA  1 
ATOM   3324  C C   . GLY B 2 101 ? 138.504 97.874  81.202  1.00 95.11  ? 76  GLY B C   1 
ATOM   3325  O O   . GLY B 2 101 ? 139.679 97.500  81.085  1.00 93.75  ? 76  GLY B O   1 
ATOM   3326  N N   . ILE B 2 102 ? 138.070 98.529  82.273  1.00 92.77  ? 77  ILE B N   1 
ATOM   3327  C CA  . ILE B 2 102 ? 138.921 98.819  83.420  1.00 89.68  ? 77  ILE B CA  1 
ATOM   3328  C C   . ILE B 2 102 ? 138.431 97.971  84.591  1.00 90.20  ? 77  ILE B C   1 
ATOM   3329  O O   . ILE B 2 102 ? 137.334 98.217  85.114  1.00 91.20  ? 77  ILE B O   1 
ATOM   3330  C CB  . ILE B 2 102 ? 138.904 100.312 83.773  1.00 84.62  ? 77  ILE B CB  1 
ATOM   3331  C CG1 . ILE B 2 102 ? 139.217 101.157 82.538  1.00 87.54  ? 77  ILE B CG1 1 
ATOM   3332  C CG2 . ILE B 2 102 ? 139.896 100.606 84.889  1.00 78.26  ? 77  ILE B CG2 1 
ATOM   3333  C CD1 . ILE B 2 102 ? 139.140 102.646 82.784  1.00 82.90  ? 77  ILE B CD1 1 
ATOM   3334  N N   . PRO B 2 103 ? 139.196 96.969  85.041  1.00 90.40  ? 78  PRO B N   1 
ATOM   3335  C CA  . PRO B 2 103 ? 138.799 96.168  86.205  1.00 87.11  ? 78  PRO B CA  1 
ATOM   3336  C C   . PRO B 2 103 ? 139.134 96.858  87.526  1.00 83.62  ? 78  PRO B C   1 
ATOM   3337  O O   . PRO B 2 103 ? 139.671 96.247  88.451  1.00 81.86  ? 78  PRO B O   1 
ATOM   3338  C CB  . PRO B 2 103 ? 139.603 94.879  86.015  1.00 80.97  ? 78  PRO B CB  1 
ATOM   3339  C CG  . PRO B 2 103 ? 140.851 95.340  85.346  1.00 82.16  ? 78  PRO B CG  1 
ATOM   3340  C CD  . PRO B 2 103 ? 140.446 96.479  84.436  1.00 89.07  ? 78  PRO B CD  1 
ATOM   3341  N N   . LEU B 2 104 ? 138.807 98.144  87.611  1.00 81.54  ? 79  LEU B N   1 
ATOM   3342  C CA  . LEU B 2 104 ? 139.109 98.963  88.772  1.00 77.36  ? 79  LEU B CA  1 
ATOM   3343  C C   . LEU B 2 104 ? 137.939 99.898  89.029  1.00 73.56  ? 79  LEU B C   1 
ATOM   3344  O O   . LEU B 2 104 ? 137.240 100.313 88.102  1.00 73.78  ? 79  LEU B O   1 
ATOM   3345  C CB  . LEU B 2 104 ? 140.398 99.774  88.584  1.00 77.23  ? 79  LEU B CB  1 
ATOM   3346  C CG  . LEU B 2 104 ? 141.705 98.985  88.501  1.00 83.18  ? 79  LEU B CG  1 
ATOM   3347  C CD1 . LEU B 2 104 ? 142.860 99.895  88.109  1.00 86.39  ? 79  LEU B CD1 1 
ATOM   3348  C CD2 . LEU B 2 104 ? 141.992 98.285  89.819  1.00 81.77  ? 79  LEU B CD2 1 
ATOM   3349  N N   . ASN B 2 105 ? 137.737 100.229 90.298  1.00 66.61  ? 80  ASN B N   1 
ATOM   3350  C CA  . ASN B 2 105 ? 136.776 101.250 90.685  1.00 61.46  ? 80  ASN B CA  1 
ATOM   3351  C C   . ASN B 2 105 ? 137.490 102.596 90.696  1.00 62.56  ? 80  ASN B C   1 
ATOM   3352  O O   . ASN B 2 105 ? 138.451 102.786 91.449  1.00 66.30  ? 80  ASN B O   1 
ATOM   3353  C CB  . ASN B 2 105 ? 136.182 100.914 92.051  1.00 58.10  ? 80  ASN B CB  1 
ATOM   3354  C CG  . ASN B 2 105 ? 135.463 99.581  92.044  1.00 63.10  ? 80  ASN B CG  1 
ATOM   3355  O OD1 . ASN B 2 105 ? 134.861 99.199  91.042  1.00 64.48  ? 80  ASN B OD1 1 
ATOM   3356  N ND2 . ASN B 2 105 ? 135.536 98.857  93.152  1.00 65.83  ? 80  ASN B ND2 1 
ATOM   3357  N N   . LEU B 2 106 ? 137.019 103.529 89.871  1.00 56.65  ? 81  LEU B N   1 
ATOM   3358  C CA  . LEU B 2 106 ? 137.749 104.769 89.620  1.00 46.97  ? 81  LEU B CA  1 
ATOM   3359  C C   . LEU B 2 106 ? 137.365 105.784 90.685  1.00 44.93  ? 81  LEU B C   1 
ATOM   3360  O O   . LEU B 2 106 ? 136.290 106.385 90.634  1.00 51.88  ? 81  LEU B O   1 
ATOM   3361  C CB  . LEU B 2 106 ? 137.455 105.302 88.223  1.00 47.89  ? 81  LEU B CB  1 
ATOM   3362  C CG  . LEU B 2 106 ? 137.950 104.465 87.045  1.00 65.16  ? 81  LEU B CG  1 
ATOM   3363  C CD1 . LEU B 2 106 ? 137.649 105.166 85.729  1.00 69.79  ? 81  LEU B CD1 1 
ATOM   3364  C CD2 . LEU B 2 106 ? 139.435 104.181 87.181  1.00 71.48  ? 81  LEU B CD2 1 
ATOM   3365  N N   . THR B 2 107 ? 138.255 105.978 91.650  1.00 44.32  ? 82  THR B N   1 
ATOM   3366  C CA  . THR B 2 107 ? 138.156 107.101 92.566  1.00 43.12  ? 82  THR B CA  1 
ATOM   3367  C C   . THR B 2 107 ? 138.705 108.358 91.906  1.00 47.35  ? 82  THR B C   1 
ATOM   3368  O O   . THR B 2 107 ? 139.848 108.374 91.438  1.00 52.32  ? 82  THR B O   1 
ATOM   3369  C CB  . THR B 2 107 ? 138.919 106.809 93.853  1.00 46.78  ? 82  THR B CB  1 
ATOM   3370  O OG1 . THR B 2 107 ? 138.399 105.622 94.466  1.00 42.53  ? 82  THR B OG1 1 
ATOM   3371  C CG2 . THR B 2 107 ? 138.793 107.969 94.799  1.00 42.34  ? 82  THR B CG2 1 
ATOM   3372  N N   . LEU B 2 108 ? 137.895 109.409 91.871  1.00 41.27  ? 83  LEU B N   1 
ATOM   3373  C CA  . LEU B 2 108 ? 138.262 110.643 91.199  1.00 46.96  ? 83  LEU B CA  1 
ATOM   3374  C C   . LEU B 2 108 ? 138.334 111.781 92.205  1.00 52.31  ? 83  LEU B C   1 
ATOM   3375  O O   . LEU B 2 108 ? 137.639 111.771 93.226  1.00 48.92  ? 83  LEU B O   1 
ATOM   3376  C CB  . LEU B 2 108 ? 137.255 110.991 90.099  1.00 42.04  ? 83  LEU B CB  1 
ATOM   3377  C CG  . LEU B 2 108 ? 137.076 109.951 88.995  1.00 37.43  ? 83  LEU B CG  1 
ATOM   3378  C CD1 . LEU B 2 108 ? 135.949 110.353 88.063  1.00 36.96  ? 83  LEU B CD1 1 
ATOM   3379  C CD2 . LEU B 2 108 ? 138.369 109.773 88.222  1.00 41.08  ? 83  LEU B CD2 1 
ATOM   3380  N N   . ASP B 2 109 ? 139.218 112.738 91.919  1.00 51.69  ? 84  ASP B N   1 
ATOM   3381  C CA  . ASP B 2 109 ? 139.361 113.955 92.711  1.00 48.94  ? 84  ASP B CA  1 
ATOM   3382  C C   . ASP B 2 109 ? 137.994 114.515 93.081  1.00 49.32  ? 84  ASP B C   1 
ATOM   3383  O O   . ASP B 2 109 ? 137.101 114.606 92.238  1.00 51.87  ? 84  ASP B O   1 
ATOM   3384  C CB  . ASP B 2 109 ? 140.169 114.992 91.927  1.00 49.01  ? 84  ASP B CB  1 
ATOM   3385  C CG  . ASP B 2 109 ? 140.396 116.273 92.708  1.00 58.86  ? 84  ASP B CG  1 
ATOM   3386  O OD1 . ASP B 2 109 ? 140.139 116.290 93.930  1.00 57.12  ? 84  ASP B OD1 1 
ATOM   3387  O OD2 . ASP B 2 109 ? 140.841 117.266 92.098  1.00 67.74  ? 84  ASP B OD2 1 
ATOM   3388  N N   . ASN B 2 110 ? 137.838 114.893 94.352  1.00 47.31  ? 85  ASN B N   1 
ATOM   3389  C CA  . ASN B 2 110 ? 136.520 115.253 94.865  1.00 46.23  ? 85  ASN B CA  1 
ATOM   3390  C C   . ASN B 2 110 ? 135.887 116.421 94.118  1.00 49.15  ? 85  ASN B C   1 
ATOM   3391  O O   . ASN B 2 110 ? 134.662 116.573 94.162  1.00 48.91  ? 85  ASN B O   1 
ATOM   3392  C CB  . ASN B 2 110 ? 136.620 115.580 96.355  1.00 41.55  ? 85  ASN B CB  1 
ATOM   3393  C CG  . ASN B 2 110 ? 137.370 116.868 96.620  1.00 45.72  ? 85  ASN B CG  1 
ATOM   3394  O OD1 . ASN B 2 110 ? 136.809 117.960 96.529  1.00 47.47  ? 85  ASN B OD1 1 
ATOM   3395  N ND2 . ASN B 2 110 ? 138.651 116.748 96.945  1.00 44.14  ? 85  ASN B ND2 1 
ATOM   3396  N N   . ARG B 2 111 ? 136.685 117.250 93.442  1.00 52.71  ? 86  ARG B N   1 
ATOM   3397  C CA  . ARG B 2 111 ? 136.132 118.385 92.711  1.00 54.15  ? 86  ARG B CA  1 
ATOM   3398  C C   . ARG B 2 111 ? 135.281 117.967 91.517  1.00 58.16  ? 86  ARG B C   1 
ATOM   3399  O O   . ARG B 2 111 ? 134.514 118.790 91.006  1.00 58.02  ? 86  ARG B O   1 
ATOM   3400  C CB  . ARG B 2 111 ? 137.257 119.309 92.243  1.00 54.33  ? 86  ARG B CB  1 
ATOM   3401  C CG  . ARG B 2 111 ? 138.135 118.719 91.153  1.00 57.90  ? 86  ARG B CG  1 
ATOM   3402  C CD  . ARG B 2 111 ? 139.198 119.710 90.716  1.00 66.73  ? 86  ARG B CD  1 
ATOM   3403  N NE  . ARG B 2 111 ? 140.018 120.147 91.840  1.00 74.58  ? 86  ARG B NE  1 
ATOM   3404  C CZ  . ARG B 2 111 ? 140.902 121.134 91.785  1.00 76.34  ? 86  ARG B CZ  1 
ATOM   3405  N NH1 . ARG B 2 111 ? 141.112 121.813 90.669  1.00 74.59  ? 86  ARG B NH1 1 
ATOM   3406  N NH2 . ARG B 2 111 ? 141.591 121.449 92.878  1.00 75.23  ? 86  ARG B NH2 1 
ATOM   3407  N N   . VAL B 2 112 ? 135.406 116.723 91.046  1.00 55.24  ? 87  VAL B N   1 
ATOM   3408  C CA  . VAL B 2 112 ? 134.566 116.266 89.943  1.00 49.55  ? 87  VAL B CA  1 
ATOM   3409  C C   . VAL B 2 112 ? 133.101 116.172 90.352  1.00 51.75  ? 87  VAL B C   1 
ATOM   3410  O O   . VAL B 2 112 ? 132.220 116.188 89.485  1.00 55.48  ? 87  VAL B O   1 
ATOM   3411  C CB  . VAL B 2 112 ? 135.059 114.909 89.398  1.00 46.21  ? 87  VAL B CB  1 
ATOM   3412  C CG1 . VAL B 2 112 ? 134.775 113.791 90.387  1.00 47.91  ? 87  VAL B CG1 1 
ATOM   3413  C CG2 . VAL B 2 112 ? 134.442 114.608 88.039  1.00 48.60  ? 87  VAL B CG2 1 
ATOM   3414  N N   . ALA B 2 113 ? 132.813 116.086 91.655  1.00 50.99  ? 88  ALA B N   1 
ATOM   3415  C CA  . ALA B 2 113 ? 131.426 116.014 92.103  1.00 55.85  ? 88  ALA B CA  1 
ATOM   3416  C C   . ALA B 2 113 ? 130.613 117.209 91.628  1.00 58.65  ? 88  ALA B C   1 
ATOM   3417  O O   . ALA B 2 113 ? 129.412 117.076 91.364  1.00 62.38  ? 88  ALA B O   1 
ATOM   3418  C CB  . ALA B 2 113 ? 131.372 115.913 93.627  1.00 45.57  ? 88  ALA B CB  1 
ATOM   3419  N N   . ASP B 2 114 ? 131.240 118.380 91.518  1.00 56.23  ? 89  ASP B N   1 
ATOM   3420  C CA  . ASP B 2 114 ? 130.540 119.556 91.022  1.00 60.41  ? 89  ASP B CA  1 
ATOM   3421  C C   . ASP B 2 114 ? 130.128 119.409 89.562  1.00 61.93  ? 89  ASP B C   1 
ATOM   3422  O O   . ASP B 2 114 ? 129.264 120.158 89.096  1.00 66.64  ? 89  ASP B O   1 
ATOM   3423  C CB  . ASP B 2 114 ? 131.420 120.792 91.201  1.00 69.24  ? 89  ASP B CB  1 
ATOM   3424  C CG  . ASP B 2 114 ? 131.699 121.098 92.658  1.00 73.14  ? 89  ASP B CG  1 
ATOM   3425  O OD1 . ASP B 2 114 ? 130.758 121.018 93.474  1.00 79.70  ? 89  ASP B OD1 1 
ATOM   3426  O OD2 . ASP B 2 114 ? 132.861 121.412 92.990  1.00 68.24  ? 89  ASP B OD2 1 
ATOM   3427  N N   . GLN B 2 115 ? 130.728 118.466 88.837  1.00 58.66  ? 90  GLN B N   1 
ATOM   3428  C CA  . GLN B 2 115 ? 130.441 118.229 87.429  1.00 57.16  ? 90  GLN B CA  1 
ATOM   3429  C C   . GLN B 2 115 ? 129.416 117.125 87.202  1.00 59.62  ? 90  GLN B C   1 
ATOM   3430  O O   . GLN B 2 115 ? 129.054 116.864 86.051  1.00 61.91  ? 90  GLN B O   1 
ATOM   3431  C CB  . GLN B 2 115 ? 131.731 117.901 86.672  1.00 57.84  ? 90  GLN B CB  1 
ATOM   3432  C CG  . GLN B 2 115 ? 132.820 118.948 86.834  1.00 61.80  ? 90  GLN B CG  1 
ATOM   3433  C CD  . GLN B 2 115 ? 134.141 118.509 86.241  1.00 68.99  ? 90  GLN B CD  1 
ATOM   3434  O OE1 . GLN B 2 115 ? 134.195 118.017 85.115  1.00 70.09  ? 90  GLN B OE1 1 
ATOM   3435  N NE2 . GLN B 2 115 ? 135.217 118.685 86.998  1.00 65.90  ? 90  GLN B NE2 1 
ATOM   3436  N N   . LEU B 2 116 ? 128.947 116.473 88.258  1.00 59.28  ? 91  LEU B N   1 
ATOM   3437  C CA  . LEU B 2 116 ? 128.032 115.347 88.156  1.00 57.99  ? 91  LEU B CA  1 
ATOM   3438  C C   . LEU B 2 116 ? 126.675 115.726 88.733  1.00 58.57  ? 91  LEU B C   1 
ATOM   3439  O O   . LEU B 2 116 ? 126.530 116.717 89.452  1.00 57.18  ? 91  LEU B O   1 
ATOM   3440  C CB  . LEU B 2 116 ? 128.590 114.124 88.891  1.00 54.40  ? 91  LEU B CB  1 
ATOM   3441  C CG  . LEU B 2 116 ? 129.918 113.540 88.412  1.00 53.56  ? 91  LEU B CG  1 
ATOM   3442  C CD1 . LEU B 2 116 ? 130.369 112.437 89.353  1.00 42.22  ? 91  LEU B CD1 1 
ATOM   3443  C CD2 . LEU B 2 116 ? 129.777 113.011 86.999  1.00 60.28  ? 91  LEU B CD2 1 
ATOM   3444  N N   . TRP B 2 117 ? 125.675 114.905 88.424  1.00 60.06  ? 92  TRP B N   1 
ATOM   3445  C CA  . TRP B 2 117 ? 124.370 115.052 89.049  1.00 57.64  ? 92  TRP B CA  1 
ATOM   3446  C C   . TRP B 2 117 ? 124.363 114.316 90.379  1.00 49.70  ? 92  TRP B C   1 
ATOM   3447  O O   . TRP B 2 117 ? 124.720 113.136 90.449  1.00 47.77  ? 92  TRP B O   1 
ATOM   3448  C CB  . TRP B 2 117 ? 123.263 114.501 88.149  1.00 56.98  ? 92  TRP B CB  1 
ATOM   3449  C CG  . TRP B 2 117 ? 121.883 114.591 88.761  1.00 58.93  ? 92  TRP B CG  1 
ATOM   3450  C CD1 . TRP B 2 117 ? 120.964 115.577 88.552  1.00 59.80  ? 92  TRP B CD1 1 
ATOM   3451  C CD2 . TRP B 2 117 ? 121.283 113.681 89.697  1.00 59.17  ? 92  TRP B CD2 1 
ATOM   3452  N NE1 . TRP B 2 117 ? 119.829 115.334 89.282  1.00 57.45  ? 92  TRP B NE1 1 
ATOM   3453  C CE2 . TRP B 2 117 ? 119.999 114.178 89.996  1.00 56.66  ? 92  TRP B CE2 1 
ATOM   3454  C CE3 . TRP B 2 117 ? 121.705 112.497 90.308  1.00 58.90  ? 92  TRP B CE3 1 
ATOM   3455  C CZ2 . TRP B 2 117 ? 119.135 113.531 90.875  1.00 55.85  ? 92  TRP B CZ2 1 
ATOM   3456  C CZ3 . TRP B 2 117 ? 120.843 111.856 91.180  1.00 50.89  ? 92  TRP B CZ3 1 
ATOM   3457  C CH2 . TRP B 2 117 ? 119.574 112.374 91.455  1.00 52.01  ? 92  TRP B CH2 1 
ATOM   3458  N N   . VAL B 2 118 ? 123.975 115.017 91.432  1.00 45.12  ? 93  VAL B N   1 
ATOM   3459  C CA  . VAL B 2 118 ? 123.854 114.420 92.757  1.00 42.43  ? 93  VAL B CA  1 
ATOM   3460  C C   . VAL B 2 118 ? 122.435 114.679 93.241  1.00 49.18  ? 93  VAL B C   1 
ATOM   3461  O O   . VAL B 2 118 ? 121.767 115.618 92.775  1.00 48.69  ? 93  VAL B O   1 
ATOM   3462  C CB  . VAL B 2 118 ? 124.907 114.983 93.738  1.00 39.39  ? 93  VAL B CB  1 
ATOM   3463  C CG1 . VAL B 2 118 ? 126.307 114.682 93.239  1.00 40.45  ? 93  VAL B CG1 1 
ATOM   3464  C CG2 . VAL B 2 118 ? 124.713 116.473 93.924  1.00 42.55  ? 93  VAL B CG2 1 
ATOM   3465  N N   . PRO B 2 119 ? 121.931 113.856 94.159  1.00 52.50  ? 94  PRO B N   1 
ATOM   3466  C CA  . PRO B 2 119 ? 120.583 114.087 94.685  1.00 49.95  ? 94  PRO B CA  1 
ATOM   3467  C C   . PRO B 2 119 ? 120.508 115.416 95.419  1.00 51.28  ? 94  PRO B C   1 
ATOM   3468  O O   . PRO B 2 119 ? 121.484 115.882 96.011  1.00 54.87  ? 94  PRO B O   1 
ATOM   3469  C CB  . PRO B 2 119 ? 120.356 112.903 95.633  1.00 45.36  ? 94  PRO B CB  1 
ATOM   3470  C CG  . PRO B 2 119 ? 121.374 111.890 95.247  1.00 46.44  ? 94  PRO B CG  1 
ATOM   3471  C CD  . PRO B 2 119 ? 122.545 112.647 94.731  1.00 48.58  ? 94  PRO B CD  1 
ATOM   3472  N N   . ASP B 2 120 ? 119.327 116.024 95.382  1.00 50.48  ? 95  ASP B N   1 
ATOM   3473  C CA  . ASP B 2 120 ? 119.083 117.274 96.100  1.00 49.14  ? 95  ASP B CA  1 
ATOM   3474  C C   . ASP B 2 120 ? 118.678 116.995 97.543  1.00 46.33  ? 95  ASP B C   1 
ATOM   3475  O O   . ASP B 2 120 ? 117.685 117.493 98.068  1.00 46.68  ? 95  ASP B O   1 
ATOM   3476  C CB  . ASP B 2 120 ? 118.025 118.094 95.371  1.00 48.04  ? 95  ASP B CB  1 
ATOM   3477  C CG  . ASP B 2 120 ? 116.659 117.436 95.386  1.00 46.99  ? 95  ASP B CG  1 
ATOM   3478  O OD1 . ASP B 2 120 ? 116.597 116.189 95.388  1.00 45.92  ? 95  ASP B OD1 1 
ATOM   3479  O OD2 . ASP B 2 120 ? 115.648 118.168 95.403  1.00 46.65  ? 95  ASP B OD2 1 
ATOM   3480  N N   . THR B 2 121 ? 119.507 116.188 98.197  1.00 40.95  ? 96  THR B N   1 
ATOM   3481  C CA  . THR B 2 121 ? 119.242 115.734 99.549  1.00 32.53  ? 96  THR B CA  1 
ATOM   3482  C C   . THR B 2 121 ? 119.548 116.834 100.553 1.00 28.63  ? 96  THR B C   1 
ATOM   3483  O O   . THR B 2 121 ? 120.499 117.602 100.389 1.00 33.54  ? 96  THR B O   1 
ATOM   3484  C CB  . THR B 2 121 ? 120.096 114.502 99.855  1.00 34.17  ? 96  THR B CB  1 
ATOM   3485  O OG1 . THR B 2 121 ? 119.855 113.494 98.866  1.00 42.16  ? 96  THR B OG1 1 
ATOM   3486  C CG2 . THR B 2 121 ? 119.782 113.948 101.222 1.00 28.26  ? 96  THR B CG2 1 
ATOM   3487  N N   . TYR B 2 122 ? 118.730 116.905 101.599 1.00 26.55  ? 97  TYR B N   1 
ATOM   3488  C CA  . TYR B 2 122 ? 118.954 117.852 102.676 1.00 28.08  ? 97  TYR B CA  1 
ATOM   3489  C C   . TYR B 2 122 ? 118.398 117.256 103.956 1.00 25.78  ? 97  TYR B C   1 
ATOM   3490  O O   . TYR B 2 122 ? 117.629 116.293 103.935 1.00 31.10  ? 97  TYR B O   1 
ATOM   3491  C CB  . TYR B 2 122 ? 118.314 119.217 102.386 1.00 32.54  ? 97  TYR B CB  1 
ATOM   3492  C CG  . TYR B 2 122 ? 116.815 119.266 102.568 1.00 31.72  ? 97  TYR B CG  1 
ATOM   3493  C CD1 . TYR B 2 122 ? 115.962 118.684 101.644 1.00 33.02  ? 97  TYR B CD1 1 
ATOM   3494  C CD2 . TYR B 2 122 ? 116.252 119.911 103.661 1.00 28.65  ? 97  TYR B CD2 1 
ATOM   3495  C CE1 . TYR B 2 122 ? 114.595 118.732 101.809 1.00 33.19  ? 97  TYR B CE1 1 
ATOM   3496  C CE2 . TYR B 2 122 ? 114.886 119.966 103.831 1.00 32.81  ? 97  TYR B CE2 1 
ATOM   3497  C CZ  . TYR B 2 122 ? 114.062 119.374 102.902 1.00 36.58  ? 97  TYR B CZ  1 
ATOM   3498  O OH  . TYR B 2 122 ? 112.698 119.423 103.061 1.00 37.78  ? 97  TYR B OH  1 
ATOM   3499  N N   . PHE B 2 123 ? 118.802 117.838 105.074 1.00 24.06  ? 98  PHE B N   1 
ATOM   3500  C CA  . PHE B 2 123 ? 118.374 117.398 106.393 1.00 22.48  ? 98  PHE B CA  1 
ATOM   3501  C C   . PHE B 2 123 ? 117.296 118.348 106.890 1.00 26.65  ? 98  PHE B C   1 
ATOM   3502  O O   . PHE B 2 123 ? 117.544 119.545 107.050 1.00 32.33  ? 98  PHE B O   1 
ATOM   3503  C CB  . PHE B 2 123 ? 119.569 117.340 107.338 1.00 26.46  ? 98  PHE B CB  1 
ATOM   3504  C CG  . PHE B 2 123 ? 120.716 116.555 106.779 1.00 28.39  ? 98  PHE B CG  1 
ATOM   3505  C CD1 . PHE B 2 123 ? 120.601 115.193 106.576 1.00 21.95  ? 98  PHE B CD1 1 
ATOM   3506  C CD2 . PHE B 2 123 ? 121.890 117.184 106.407 1.00 31.42  ? 98  PHE B CD2 1 
ATOM   3507  C CE1 . PHE B 2 123 ? 121.642 114.470 106.043 1.00 22.30  ? 98  PHE B CE1 1 
ATOM   3508  C CE2 . PHE B 2 123 ? 122.934 116.465 105.872 1.00 24.87  ? 98  PHE B CE2 1 
ATOM   3509  C CZ  . PHE B 2 123 ? 122.809 115.107 105.689 1.00 24.40  ? 98  PHE B CZ  1 
ATOM   3510  N N   . LEU B 2 124 ? 116.094 117.816 107.111 1.00 31.80  ? 99  LEU B N   1 
ATOM   3511  C CA  . LEU B 2 124 ? 114.936 118.676 107.325 1.00 32.45  ? 99  LEU B CA  1 
ATOM   3512  C C   . LEU B 2 124 ? 115.021 119.426 108.649 1.00 32.80  ? 99  LEU B C   1 
ATOM   3513  O O   . LEU B 2 124 ? 114.507 120.545 108.755 1.00 36.83  ? 99  LEU B O   1 
ATOM   3514  C CB  . LEU B 2 124 ? 113.658 117.838 107.252 1.00 32.82  ? 99  LEU B CB  1 
ATOM   3515  C CG  . LEU B 2 124 ? 112.312 118.482 107.582 1.00 40.27  ? 99  LEU B CG  1 
ATOM   3516  C CD1 . LEU B 2 124 ? 111.264 118.033 106.582 1.00 43.07  ? 99  LEU B CD1 1 
ATOM   3517  C CD2 . LEU B 2 124 ? 111.878 118.125 108.994 1.00 38.36  ? 99  LEU B CD2 1 
ATOM   3518  N N   . ASN B 2 125 ? 115.660 118.843 109.662 1.00 30.37  ? 100 ASN B N   1 
ATOM   3519  C CA  . ASN B 2 125 ? 115.728 119.456 110.982 1.00 30.16  ? 100 ASN B CA  1 
ATOM   3520  C C   . ASN B 2 125 ? 117.122 119.975 111.327 1.00 33.81  ? 100 ASN B C   1 
ATOM   3521  O O   . ASN B 2 125 ? 117.418 120.188 112.506 1.00 39.98  ? 100 ASN B O   1 
ATOM   3522  C CB  . ASN B 2 125 ? 115.257 118.466 112.047 1.00 31.48  ? 100 ASN B CB  1 
ATOM   3523  C CG  . ASN B 2 125 ? 116.121 117.225 112.113 1.00 31.88  ? 100 ASN B CG  1 
ATOM   3524  O OD1 . ASN B 2 125 ? 116.485 116.654 111.088 1.00 32.18  ? 100 ASN B OD1 1 
ATOM   3525  N ND2 . ASN B 2 125 ? 116.455 116.800 113.326 1.00 34.55  ? 100 ASN B ND2 1 
ATOM   3526  N N   . ASP B 2 126 ? 117.987 120.187 110.337 1.00 31.07  ? 101 ASP B N   1 
ATOM   3527  C CA  . ASP B 2 126 ? 119.324 120.694 110.624 1.00 30.42  ? 101 ASP B CA  1 
ATOM   3528  C C   . ASP B 2 126 ? 119.310 122.213 110.766 1.00 31.27  ? 101 ASP B C   1 
ATOM   3529  O O   . ASP B 2 126 ? 118.656 122.916 109.990 1.00 30.51  ? 101 ASP B O   1 
ATOM   3530  C CB  . ASP B 2 126 ? 120.322 120.263 109.544 1.00 28.49  ? 101 ASP B CB  1 
ATOM   3531  C CG  . ASP B 2 126 ? 120.296 121.151 108.313 1.00 33.48  ? 101 ASP B CG  1 
ATOM   3532  O OD1 . ASP B 2 126 ? 119.201 121.487 107.825 1.00 42.88  ? 101 ASP B OD1 1 
ATOM   3533  O OD2 . ASP B 2 126 ? 121.387 121.513 107.825 1.00 29.39  ? 101 ASP B OD2 1 
ATOM   3534  N N   . LYS B 2 127 ? 119.984 122.712 111.801 1.00 30.37  ? 102 LYS B N   1 
ATOM   3535  C CA  . LYS B 2 127 ? 120.071 124.149 112.043 1.00 26.92  ? 102 LYS B CA  1 
ATOM   3536  C C   . LYS B 2 127 ? 121.311 124.739 111.377 1.00 29.76  ? 102 LYS B C   1 
ATOM   3537  O O   . LYS B 2 127 ? 121.216 125.698 110.605 1.00 34.61  ? 102 LYS B O   1 
ATOM   3538  C CB  . LYS B 2 127 ? 120.062 124.442 113.546 1.00 26.78  ? 102 LYS B CB  1 
ATOM   3539  C CG  . LYS B 2 127 ? 118.903 123.808 114.286 1.00 34.62  ? 102 LYS B CG  1 
ATOM   3540  C CD  . LYS B 2 127 ? 119.088 123.914 115.783 1.00 41.17  ? 102 LYS B CD  1 
ATOM   3541  C CE  . LYS B 2 127 ? 118.909 125.343 116.258 1.00 46.73  ? 102 LYS B CE  1 
ATOM   3542  N NZ  . LYS B 2 127 ? 118.936 125.439 117.742 1.00 50.89  ? 102 LYS B NZ  1 
ATOM   3543  N N   . LYS B 2 128 ? 122.482 124.187 111.685 1.00 29.44  ? 103 LYS B N   1 
ATOM   3544  C CA  . LYS B 2 128 ? 123.742 124.633 111.107 1.00 26.93  ? 103 LYS B CA  1 
ATOM   3545  C C   . LYS B 2 128 ? 124.557 123.406 110.733 1.00 26.45  ? 103 LYS B C   1 
ATOM   3546  O O   . LYS B 2 128 ? 124.708 122.492 111.549 1.00 28.07  ? 103 LYS B O   1 
ATOM   3547  C CB  . LYS B 2 128 ? 124.513 125.511 112.097 1.00 32.49  ? 103 LYS B CB  1 
ATOM   3548  C CG  . LYS B 2 128 ? 125.668 126.292 111.502 1.00 39.66  ? 103 LYS B CG  1 
ATOM   3549  C CD  . LYS B 2 128 ? 126.359 127.114 112.577 1.00 49.78  ? 103 LYS B CD  1 
ATOM   3550  C CE  . LYS B 2 128 ? 127.673 127.693 112.084 1.00 64.10  ? 103 LYS B CE  1 
ATOM   3551  N NZ  . LYS B 2 128 ? 128.405 128.400 113.172 1.00 60.92  ? 103 LYS B NZ  1 
ATOM   3552  N N   . SER B 2 129 ? 125.082 123.385 109.510 1.00 27.87  ? 104 SER B N   1 
ATOM   3553  C CA  . SER B 2 129 ? 125.891 122.261 109.064 1.00 26.32  ? 104 SER B CA  1 
ATOM   3554  C C   . SER B 2 129 ? 126.912 122.732 108.039 1.00 28.43  ? 104 SER B C   1 
ATOM   3555  O O   . SER B 2 129 ? 126.746 123.772 107.399 1.00 35.46  ? 104 SER B O   1 
ATOM   3556  C CB  . SER B 2 129 ? 125.022 121.149 108.469 1.00 23.45  ? 104 SER B CB  1 
ATOM   3557  O OG  . SER B 2 129 ? 124.492 121.537 107.217 1.00 21.26  ? 104 SER B OG  1 
ATOM   3558  N N   . PHE B 2 130 ? 127.974 121.942 107.890 1.00 23.99  ? 105 PHE B N   1 
ATOM   3559  C CA  . PHE B 2 130 ? 129.016 122.237 106.918 1.00 23.75  ? 105 PHE B CA  1 
ATOM   3560  C C   . PHE B 2 130 ? 129.725 120.946 106.540 1.00 21.58  ? 105 PHE B C   1 
ATOM   3561  O O   . PHE B 2 130 ? 129.662 119.948 107.261 1.00 23.06  ? 105 PHE B O   1 
ATOM   3562  C CB  . PHE B 2 130 ? 130.025 123.248 107.470 1.00 26.03  ? 105 PHE B CB  1 
ATOM   3563  C CG  . PHE B 2 130 ? 130.778 122.756 108.675 1.00 27.66  ? 105 PHE B CG  1 
ATOM   3564  C CD1 . PHE B 2 130 ? 130.190 122.758 109.928 1.00 28.62  ? 105 PHE B CD1 1 
ATOM   3565  C CD2 . PHE B 2 130 ? 132.070 122.277 108.551 1.00 26.19  ? 105 PHE B CD2 1 
ATOM   3566  C CE1 . PHE B 2 130 ? 130.879 122.303 111.033 1.00 29.25  ? 105 PHE B CE1 1 
ATOM   3567  C CE2 . PHE B 2 130 ? 132.762 121.818 109.653 1.00 27.81  ? 105 PHE B CE2 1 
ATOM   3568  C CZ  . PHE B 2 130 ? 132.166 121.832 110.895 1.00 30.31  ? 105 PHE B CZ  1 
ATOM   3569  N N   . VAL B 2 131 ? 130.407 120.983 105.398 1.00 21.53  ? 106 VAL B N   1 
ATOM   3570  C CA  . VAL B 2 131 ? 131.321 119.926 104.981 1.00 20.58  ? 106 VAL B CA  1 
ATOM   3571  C C   . VAL B 2 131 ? 132.726 120.334 105.393 1.00 28.81  ? 106 VAL B C   1 
ATOM   3572  O O   . VAL B 2 131 ? 133.147 121.470 105.144 1.00 35.15  ? 106 VAL B O   1 
ATOM   3573  C CB  . VAL B 2 131 ? 131.241 119.672 103.466 1.00 19.82  ? 106 VAL B CB  1 
ATOM   3574  C CG1 . VAL B 2 131 ? 132.076 118.460 103.094 1.00 18.55  ? 106 VAL B CG1 1 
ATOM   3575  C CG2 . VAL B 2 131 ? 129.803 119.473 103.035 1.00 17.70  ? 106 VAL B CG2 1 
ATOM   3576  N N   . HIS B 2 132 ? 133.450 119.417 106.024 1.00 28.17  ? 107 HIS B N   1 
ATOM   3577  C CA  . HIS B 2 132 ? 134.827 119.689 106.410 1.00 28.37  ? 107 HIS B CA  1 
ATOM   3578  C C   . HIS B 2 132 ? 135.688 119.932 105.174 1.00 26.89  ? 107 HIS B C   1 
ATOM   3579  O O   . HIS B 2 132 ? 135.464 119.351 104.110 1.00 26.48  ? 107 HIS B O   1 
ATOM   3580  C CB  . HIS B 2 132 ? 135.373 118.515 107.212 1.00 23.45  ? 107 HIS B CB  1 
ATOM   3581  C CG  . HIS B 2 132 ? 134.674 118.302 108.516 1.00 22.75  ? 107 HIS B CG  1 
ATOM   3582  N ND1 . HIS B 2 132 ? 135.237 118.627 109.730 1.00 30.81  ? 107 HIS B ND1 1 
ATOM   3583  C CD2 . HIS B 2 132 ? 133.450 117.793 108.793 1.00 20.34  ? 107 HIS B CD2 1 
ATOM   3584  C CE1 . HIS B 2 132 ? 134.392 118.323 110.699 1.00 26.25  ? 107 HIS B CE1 1 
ATOM   3585  N NE2 . HIS B 2 132 ? 133.299 117.818 110.157 1.00 20.54  ? 107 HIS B NE2 1 
ATOM   3586  N N   . GLY B 2 133 ? 136.687 120.801 105.317 1.00 22.85  ? 108 GLY B N   1 
ATOM   3587  C CA  . GLY B 2 133 ? 137.435 121.237 104.153 1.00 24.06  ? 108 GLY B CA  1 
ATOM   3588  C C   . GLY B 2 133 ? 138.940 121.315 104.315 1.00 26.53  ? 108 GLY B C   1 
ATOM   3589  O O   . GLY B 2 133 ? 139.606 122.025 103.558 1.00 28.00  ? 108 GLY B O   1 
ATOM   3590  N N   . VAL B 2 134 ? 139.491 120.600 105.292 1.00 26.10  ? 109 VAL B N   1 
ATOM   3591  C CA  . VAL B 2 134 ? 140.933 120.495 105.488 1.00 24.25  ? 109 VAL B CA  1 
ATOM   3592  C C   . VAL B 2 134 ? 141.321 119.026 105.395 1.00 22.27  ? 109 VAL B C   1 
ATOM   3593  O O   . VAL B 2 134 ? 140.696 118.179 106.044 1.00 26.70  ? 109 VAL B O   1 
ATOM   3594  C CB  . VAL B 2 134 ? 141.361 121.101 106.836 1.00 24.96  ? 109 VAL B CB  1 
ATOM   3595  C CG1 . VAL B 2 134 ? 142.825 120.817 107.123 1.00 21.57  ? 109 VAL B CG1 1 
ATOM   3596  C CG2 . VAL B 2 134 ? 141.106 122.597 106.834 1.00 31.40  ? 109 VAL B CG2 1 
ATOM   3597  N N   . THR B 2 135 ? 142.347 118.717 104.601 1.00 19.61  ? 110 THR B N   1 
ATOM   3598  C CA  . THR B 2 135 ? 143.110 119.683 103.810 1.00 21.71  ? 110 THR B CA  1 
ATOM   3599  C C   . THR B 2 135 ? 142.347 120.116 102.563 1.00 23.27  ? 110 THR B C   1 
ATOM   3600  O O   . THR B 2 135 ? 142.445 121.263 102.132 1.00 23.43  ? 110 THR B O   1 
ATOM   3601  C CB  . THR B 2 135 ? 144.475 119.108 103.398 1.00 21.10  ? 110 THR B CB  1 
ATOM   3602  O OG1 . THR B 2 135 ? 144.282 117.922 102.619 1.00 23.80  ? 110 THR B OG1 1 
ATOM   3603  C CG2 . THR B 2 135 ? 145.295 118.768 104.628 1.00 18.58  ? 110 THR B CG2 1 
ATOM   3604  N N   . VAL B 2 136 ? 141.594 119.184 101.985 1.00 20.95  ? 111 VAL B N   1 
ATOM   3605  C CA  . VAL B 2 136 ? 140.724 119.485 100.856 1.00 22.81  ? 111 VAL B CA  1 
ATOM   3606  C C   . VAL B 2 136 ? 139.299 119.223 101.315 1.00 26.35  ? 111 VAL B C   1 
ATOM   3607  O O   . VAL B 2 136 ? 139.076 118.837 102.468 1.00 27.79  ? 111 VAL B O   1 
ATOM   3608  C CB  . VAL B 2 136 ? 141.079 118.646 99.617  1.00 21.54  ? 111 VAL B CB  1 
ATOM   3609  C CG1 . VAL B 2 136 ? 142.532 118.860 99.226  1.00 21.68  ? 111 VAL B CG1 1 
ATOM   3610  C CG2 . VAL B 2 136 ? 140.802 117.183 99.883  1.00 20.82  ? 111 VAL B CG2 1 
ATOM   3611  N N   . LYS B 2 137 ? 138.325 119.438 100.434 1.00 27.96  ? 112 LYS B N   1 
ATOM   3612  C CA  . LYS B 2 137 ? 136.945 119.133 100.784 1.00 27.27  ? 112 LYS B CA  1 
ATOM   3613  C C   . LYS B 2 137 ? 136.784 117.650 101.087 1.00 31.58  ? 112 LYS B C   1 
ATOM   3614  O O   . LYS B 2 137 ? 137.153 116.794 100.279 1.00 34.42  ? 112 LYS B O   1 
ATOM   3615  C CB  . LYS B 2 137 ? 136.013 119.543 99.645  1.00 30.17  ? 112 LYS B CB  1 
ATOM   3616  C CG  . LYS B 2 137 ? 134.539 119.458 99.994  1.00 33.50  ? 112 LYS B CG  1 
ATOM   3617  C CD  . LYS B 2 137 ? 133.731 120.517 99.269  1.00 36.28  ? 112 LYS B CD  1 
ATOM   3618  C CE  . LYS B 2 137 ? 132.286 120.510 99.736  1.00 35.67  ? 112 LYS B CE  1 
ATOM   3619  N NZ  . LYS B 2 137 ? 131.514 121.660 99.193  1.00 38.45  ? 112 LYS B NZ  1 
ATOM   3620  N N   . ASN B 2 138 ? 136.233 117.347 102.264 1.00 26.89  ? 113 ASN B N   1 
ATOM   3621  C CA  . ASN B 2 138 ? 136.032 115.961 102.691 1.00 21.49  ? 113 ASN B CA  1 
ATOM   3622  C C   . ASN B 2 138 ? 134.835 115.391 101.938 1.00 22.25  ? 113 ASN B C   1 
ATOM   3623  O O   . ASN B 2 138 ? 133.722 115.276 102.454 1.00 23.53  ? 113 ASN B O   1 
ATOM   3624  C CB  . ASN B 2 138 ? 135.863 115.864 104.201 1.00 20.77  ? 113 ASN B CB  1 
ATOM   3625  C CG  . ASN B 2 138 ? 137.115 116.266 104.956 1.00 21.72  ? 113 ASN B CG  1 
ATOM   3626  O OD1 . ASN B 2 138 ? 137.150 116.229 106.184 1.00 21.46  ? 113 ASN B OD1 1 
ATOM   3627  N ND2 . ASN B 2 138 ? 138.158 116.630 104.223 1.00 22.10  ? 113 ASN B ND2 1 
ATOM   3628  N N   . ARG B 2 139 ? 135.082 115.038 100.682 1.00 24.77  ? 114 ARG B N   1 
ATOM   3629  C CA  . ARG B 2 139 ? 134.049 114.579 99.769  1.00 28.26  ? 114 ARG B CA  1 
ATOM   3630  C C   . ARG B 2 139 ? 134.648 113.482 98.903  1.00 28.69  ? 114 ARG B C   1 
ATOM   3631  O O   . ARG B 2 139 ? 135.854 113.470 98.646  1.00 34.98  ? 114 ARG B O   1 
ATOM   3632  C CB  . ARG B 2 139 ? 133.499 115.739 98.924  1.00 29.59  ? 114 ARG B CB  1 
ATOM   3633  C CG  . ARG B 2 139 ? 132.482 115.342 97.872  1.00 32.68  ? 114 ARG B CG  1 
ATOM   3634  C CD  . ARG B 2 139 ? 131.897 116.564 97.190  1.00 37.85  ? 114 ARG B CD  1 
ATOM   3635  N NE  . ARG B 2 139 ? 132.924 117.452 96.661  1.00 47.31  ? 114 ARG B NE  1 
ATOM   3636  C CZ  . ARG B 2 139 ? 132.670 118.565 95.988  1.00 54.24  ? 114 ARG B CZ  1 
ATOM   3637  N NH1 . ARG B 2 139 ? 131.431 118.957 95.742  1.00 50.66  ? 114 ARG B NH1 1 
ATOM   3638  N NH2 . ARG B 2 139 ? 133.686 119.305 95.551  1.00 55.07  ? 114 ARG B NH2 1 
ATOM   3639  N N   . MET B 2 140 ? 133.805 112.555 98.459  1.00 24.28  ? 115 MET B N   1 
ATOM   3640  C CA  . MET B 2 140 ? 134.281 111.403 97.709  1.00 25.35  ? 115 MET B CA  1 
ATOM   3641  C C   . MET B 2 140 ? 133.319 111.073 96.584  1.00 29.04  ? 115 MET B C   1 
ATOM   3642  O O   . MET B 2 140 ? 132.102 111.053 96.785  1.00 35.74  ? 115 MET B O   1 
ATOM   3643  C CB  . MET B 2 140 ? 134.455 110.188 98.627  1.00 28.84  ? 115 MET B CB  1 
ATOM   3644  C CG  . MET B 2 140 ? 134.757 108.889 97.903  1.00 34.74  ? 115 MET B CG  1 
ATOM   3645  S SD  . MET B 2 140 ? 134.868 107.478 99.019  1.00 61.34  ? 115 MET B SD  1 
ATOM   3646  C CE  . MET B 2 140 ? 133.227 107.468 99.729  1.00 47.56  ? 115 MET B CE  1 
ATOM   3647  N N   . ILE B 2 141 ? 133.875 110.820 95.403  1.00 31.46  ? 116 ILE B N   1 
ATOM   3648  C CA  . ILE B 2 141 ? 133.155 110.228 94.284  1.00 39.37  ? 116 ILE B CA  1 
ATOM   3649  C C   . ILE B 2 141 ? 133.915 108.983 93.858  1.00 42.07  ? 116 ILE B C   1 
ATOM   3650  O O   . ILE B 2 141 ? 135.128 109.042 93.625  1.00 56.17  ? 116 ILE B O   1 
ATOM   3651  C CB  . ILE B 2 141 ? 133.017 111.212 93.108  1.00 40.70  ? 116 ILE B CB  1 
ATOM   3652  C CG1 . ILE B 2 141 ? 131.977 112.285 93.423  1.00 40.53  ? 116 ILE B CG1 1 
ATOM   3653  C CG2 . ILE B 2 141 ? 132.661 110.472 91.825  1.00 39.18  ? 116 ILE B CG2 1 
ATOM   3654  C CD1 . ILE B 2 141 ? 130.557 111.781 93.353  1.00 35.52  ? 116 ILE B CD1 1 
ATOM   3655  N N   . ARG B 2 142 ? 133.208 107.862 93.753  1.00 30.00  ? 117 ARG B N   1 
ATOM   3656  C CA  . ARG B 2 142 ? 133.816 106.613 93.320  1.00 36.49  ? 117 ARG B CA  1 
ATOM   3657  C C   . ARG B 2 142 ? 132.896 105.961 92.304  1.00 37.60  ? 117 ARG B C   1 
ATOM   3658  O O   . ARG B 2 142 ? 131.761 105.605 92.632  1.00 42.39  ? 117 ARG B O   1 
ATOM   3659  C CB  . ARG B 2 142 ? 134.062 105.685 94.514  1.00 40.72  ? 117 ARG B CB  1 
ATOM   3660  C CG  . ARG B 2 142 ? 134.819 104.412 94.185  1.00 47.17  ? 117 ARG B CG  1 
ATOM   3661  C CD  . ARG B 2 142 ? 135.015 103.561 95.431  1.00 47.50  ? 117 ARG B CD  1 
ATOM   3662  N NE  . ARG B 2 142 ? 135.729 104.291 96.472  1.00 47.87  ? 117 ARG B NE  1 
ATOM   3663  C CZ  . ARG B 2 142 ? 135.920 103.846 97.707  1.00 45.53  ? 117 ARG B CZ  1 
ATOM   3664  N NH1 . ARG B 2 142 ? 135.456 102.671 98.098  1.00 51.12  ? 117 ARG B NH1 1 
ATOM   3665  N NH2 . ARG B 2 142 ? 136.590 104.602 98.572  1.00 36.91  ? 117 ARG B NH2 1 
ATOM   3666  N N   . LEU B 2 143 ? 133.383 105.805 91.079  1.00 41.67  ? 118 LEU B N   1 
ATOM   3667  C CA  . LEU B 2 143 ? 132.627 105.141 90.031  1.00 45.90  ? 118 LEU B CA  1 
ATOM   3668  C C   . LEU B 2 143 ? 132.897 103.642 90.049  1.00 50.98  ? 118 LEU B C   1 
ATOM   3669  O O   . LEU B 2 143 ? 133.945 103.184 90.510  1.00 54.67  ? 118 LEU B O   1 
ATOM   3670  C CB  . LEU B 2 143 ? 132.976 105.726 88.663  1.00 46.44  ? 118 LEU B CB  1 
ATOM   3671  C CG  . LEU B 2 143 ? 132.795 107.242 88.547  1.00 45.02  ? 118 LEU B CG  1 
ATOM   3672  C CD1 . LEU B 2 143 ? 133.146 107.735 87.149  1.00 46.62  ? 118 LEU B CD1 1 
ATOM   3673  C CD2 . LEU B 2 143 ? 131.377 107.639 88.926  1.00 46.29  ? 118 LEU B CD2 1 
ATOM   3674  N N   . HIS B 2 144 ? 131.938 102.880 89.537  1.00 53.93  ? 119 HIS B N   1 
ATOM   3675  C CA  . HIS B 2 144 ? 132.050 101.436 89.434  1.00 54.54  ? 119 HIS B CA  1 
ATOM   3676  C C   . HIS B 2 144 ? 131.737 101.001 88.011  1.00 67.79  ? 119 HIS B C   1 
ATOM   3677  O O   . HIS B 2 144 ? 131.026 101.707 87.288  1.00 71.86  ? 119 HIS B O   1 
ATOM   3678  C CB  . HIS B 2 144 ? 131.098 100.742 90.418  1.00 47.37  ? 119 HIS B CB  1 
ATOM   3679  C CG  . HIS B 2 144 ? 131.379 101.061 91.853  1.00 47.28  ? 119 HIS B CG  1 
ATOM   3680  N ND1 . HIS B 2 144 ? 131.198 102.318 92.386  1.00 43.07  ? 119 HIS B ND1 1 
ATOM   3681  C CD2 . HIS B 2 144 ? 131.820 100.282 92.869  1.00 51.89  ? 119 HIS B CD2 1 
ATOM   3682  C CE1 . HIS B 2 144 ? 131.520 102.303 93.667  1.00 42.24  ? 119 HIS B CE1 1 
ATOM   3683  N NE2 . HIS B 2 144 ? 131.900 101.079 93.985  1.00 47.52  ? 119 HIS B NE2 1 
ATOM   3684  N N   . PRO B 2 145 ? 132.267 99.850  87.576  1.00 72.80  ? 120 PRO B N   1 
ATOM   3685  C CA  . PRO B 2 145 ? 132.081 99.448  86.168  1.00 71.13  ? 120 PRO B CA  1 
ATOM   3686  C C   . PRO B 2 145 ? 130.627 99.386  85.734  1.00 66.66  ? 120 PRO B C   1 
ATOM   3687  O O   . PRO B 2 145 ? 130.307 99.767  84.601  1.00 69.94  ? 120 PRO B O   1 
ATOM   3688  C CB  . PRO B 2 145 ? 132.752 98.069  86.112  1.00 74.85  ? 120 PRO B CB  1 
ATOM   3689  C CG  . PRO B 2 145 ? 133.751 98.091  87.215  1.00 75.10  ? 120 PRO B CG  1 
ATOM   3690  C CD  . PRO B 2 145 ? 133.146 98.921  88.307  1.00 73.08  ? 120 PRO B CD  1 
ATOM   3691  N N   . ASP B 2 146 ? 129.734 98.914  86.604  1.00 66.99  ? 121 ASP B N   1 
ATOM   3692  C CA  . ASP B 2 146 ? 128.330 98.768  86.240  1.00 74.94  ? 121 ASP B CA  1 
ATOM   3693  C C   . ASP B 2 146 ? 127.594 100.099 86.151  1.00 75.69  ? 121 ASP B C   1 
ATOM   3694  O O   . ASP B 2 146 ? 126.453 100.124 85.678  1.00 79.36  ? 121 ASP B O   1 
ATOM   3695  C CB  . ASP B 2 146 ? 127.630 97.831  87.231  1.00 76.77  ? 121 ASP B CB  1 
ATOM   3696  C CG  . ASP B 2 146 ? 127.567 98.397  88.644  1.00 73.03  ? 121 ASP B CG  1 
ATOM   3697  O OD1 . ASP B 2 146 ? 128.015 99.538  88.873  1.00 69.76  ? 121 ASP B OD1 1 
ATOM   3698  O OD2 . ASP B 2 146 ? 127.060 97.686  89.536  1.00 68.23  ? 121 ASP B OD2 1 
ATOM   3699  N N   . GLY B 2 147 ? 128.212 101.195 86.586  1.00 71.86  ? 122 GLY B N   1 
ATOM   3700  C CA  . GLY B 2 147 ? 127.572 102.494 86.627  1.00 70.88  ? 122 GLY B CA  1 
ATOM   3701  C C   . GLY B 2 147 ? 127.198 102.972 88.012  1.00 58.78  ? 122 GLY B C   1 
ATOM   3702  O O   . GLY B 2 147 ? 126.757 104.120 88.151  1.00 56.85  ? 122 GLY B O   1 
ATOM   3703  N N   . THR B 2 148 ? 127.345 102.134 89.035  1.00 54.01  ? 123 THR B N   1 
ATOM   3704  C CA  . THR B 2 148 ? 127.058 102.554 90.400  1.00 49.16  ? 123 THR B CA  1 
ATOM   3705  C C   . THR B 2 148 ? 127.933 103.740 90.779  1.00 43.03  ? 123 THR B C   1 
ATOM   3706  O O   . THR B 2 148 ? 129.140 103.741 90.522  1.00 50.45  ? 123 THR B O   1 
ATOM   3707  C CB  . THR B 2 148 ? 127.291 101.397 91.374  1.00 53.43  ? 123 THR B CB  1 
ATOM   3708  O OG1 . THR B 2 148 ? 126.403 100.317 91.061  1.00 61.47  ? 123 THR B OG1 1 
ATOM   3709  C CG2 . THR B 2 148 ? 127.046 101.843 92.808  1.00 46.06  ? 123 THR B CG2 1 
ATOM   3710  N N   . VAL B 2 149 ? 127.324 104.755 91.383  1.00 40.99  ? 124 VAL B N   1 
ATOM   3711  C CA  . VAL B 2 149 ? 128.036 105.942 91.839  1.00 38.67  ? 124 VAL B CA  1 
ATOM   3712  C C   . VAL B 2 149 ? 127.996 105.952 93.358  1.00 33.23  ? 124 VAL B C   1 
ATOM   3713  O O   . VAL B 2 149 ? 126.923 105.838 93.961  1.00 38.93  ? 124 VAL B O   1 
ATOM   3714  C CB  . VAL B 2 149 ? 127.429 107.231 91.260  1.00 39.93  ? 124 VAL B CB  1 
ATOM   3715  C CG1 . VAL B 2 149 ? 128.287 108.428 91.623  1.00 32.90  ? 124 VAL B CG1 1 
ATOM   3716  C CG2 . VAL B 2 149 ? 127.285 107.117 89.754  1.00 48.25  ? 124 VAL B CG2 1 
ATOM   3717  N N   . LEU B 2 150 ? 129.164 106.082 93.971  1.00 32.09  ? 125 LEU B N   1 
ATOM   3718  C CA  . LEU B 2 150 ? 129.302 106.289 95.405  1.00 30.76  ? 125 LEU B CA  1 
ATOM   3719  C C   . LEU B 2 150 ? 129.677 107.737 95.672  1.00 32.01  ? 125 LEU B C   1 
ATOM   3720  O O   . LEU B 2 150 ? 130.723 108.206 95.213  1.00 41.68  ? 125 LEU B O   1 
ATOM   3721  C CB  . LEU B 2 150 ? 130.349 105.345 95.994  1.00 39.62  ? 125 LEU B CB  1 
ATOM   3722  C CG  . LEU B 2 150 ? 130.836 105.645 97.413  1.00 36.05  ? 125 LEU B CG  1 
ATOM   3723  C CD1 . LEU B 2 150 ? 129.678 105.791 98.373  1.00 30.37  ? 125 LEU B CD1 1 
ATOM   3724  C CD2 . LEU B 2 150 ? 131.779 104.554 97.886  1.00 37.53  ? 125 LEU B CD2 1 
ATOM   3725  N N   . TYR B 2 151 ? 128.824 108.440 96.408  1.00 27.59  ? 126 TYR B N   1 
ATOM   3726  C CA  . TYR B 2 151 ? 129.007 109.855 96.700  1.00 28.64  ? 126 TYR B CA  1 
ATOM   3727  C C   . TYR B 2 151 ? 128.960 110.001 98.213  1.00 25.37  ? 126 TYR B C   1 
ATOM   3728  O O   . TYR B 2 151 ? 127.902 109.827 98.826  1.00 32.78  ? 126 TYR B O   1 
ATOM   3729  C CB  . TYR B 2 151 ? 127.929 110.692 96.013  1.00 32.44  ? 126 TYR B CB  1 
ATOM   3730  C CG  . TYR B 2 151 ? 127.935 112.163 96.354  1.00 30.26  ? 126 TYR B CG  1 
ATOM   3731  C CD1 . TYR B 2 151 ? 129.087 112.925 96.227  1.00 27.35  ? 126 TYR B CD1 1 
ATOM   3732  C CD2 . TYR B 2 151 ? 126.777 112.794 96.782  1.00 32.21  ? 126 TYR B CD2 1 
ATOM   3733  C CE1 . TYR B 2 151 ? 129.088 114.271 96.534  1.00 32.55  ? 126 TYR B CE1 1 
ATOM   3734  C CE2 . TYR B 2 151 ? 126.766 114.138 97.087  1.00 33.49  ? 126 TYR B CE2 1 
ATOM   3735  C CZ  . TYR B 2 151 ? 127.924 114.872 96.964  1.00 35.37  ? 126 TYR B CZ  1 
ATOM   3736  O OH  . TYR B 2 151 ? 127.916 116.213 97.268  1.00 37.30  ? 126 TYR B OH  1 
ATOM   3737  N N   . GLY B 2 152 ? 130.097 110.318 98.808  1.00 20.90  ? 127 GLY B N   1 
ATOM   3738  C CA  . GLY B 2 152 ? 130.231 110.354 100.255 1.00 19.69  ? 127 GLY B CA  1 
ATOM   3739  C C   . GLY B 2 152 ? 130.697 111.715 100.730 1.00 22.36  ? 127 GLY B C   1 
ATOM   3740  O O   . GLY B 2 152 ? 131.539 112.347 100.092 1.00 30.84  ? 127 GLY B O   1 
ATOM   3741  N N   . LEU B 2 153 ? 130.144 112.157 101.852 1.00 19.60  ? 128 LEU B N   1 
ATOM   3742  C CA  . LEU B 2 153 ? 130.514 113.423 102.459 1.00 16.41  ? 128 LEU B CA  1 
ATOM   3743  C C   . LEU B 2 153 ? 130.784 113.203 103.938 1.00 15.77  ? 128 LEU B C   1 
ATOM   3744  O O   . LEU B 2 153 ? 130.211 112.308 104.563 1.00 20.50  ? 128 LEU B O   1 
ATOM   3745  C CB  . LEU B 2 153 ? 129.426 114.491 102.279 1.00 21.00  ? 128 LEU B CB  1 
ATOM   3746  C CG  . LEU B 2 153 ? 129.034 114.847 100.845 1.00 19.77  ? 128 LEU B CG  1 
ATOM   3747  C CD1 . LEU B 2 153 ? 127.873 113.987 100.381 1.00 21.64  ? 128 LEU B CD1 1 
ATOM   3748  C CD2 . LEU B 2 153 ? 128.700 116.320 100.725 1.00 20.00  ? 128 LEU B CD2 1 
ATOM   3749  N N   . ARG B 2 154 ? 131.664 114.025 104.491 1.00 14.66  ? 129 ARG B N   1 
ATOM   3750  C CA  . ARG B 2 154 ? 131.865 114.096 105.931 1.00 14.29  ? 129 ARG B CA  1 
ATOM   3751  C C   . ARG B 2 154 ? 131.193 115.373 106.408 1.00 15.81  ? 129 ARG B C   1 
ATOM   3752  O O   . ARG B 2 154 ? 131.658 116.477 106.112 1.00 22.41  ? 129 ARG B O   1 
ATOM   3753  C CB  . ARG B 2 154 ? 133.349 114.082 106.281 1.00 17.27  ? 129 ARG B CB  1 
ATOM   3754  C CG  . ARG B 2 154 ? 133.643 113.981 107.762 1.00 17.15  ? 129 ARG B CG  1 
ATOM   3755  C CD  . ARG B 2 154 ? 135.038 113.442 107.998 1.00 17.75  ? 129 ARG B CD  1 
ATOM   3756  N NE  . ARG B 2 154 ? 136.034 114.505 108.014 1.00 21.71  ? 129 ARG B NE  1 
ATOM   3757  C CZ  . ARG B 2 154 ? 136.543 115.039 109.115 1.00 25.18  ? 129 ARG B CZ  1 
ATOM   3758  N NH1 . ARG B 2 154 ? 136.161 114.638 110.316 1.00 24.57  ? 129 ARG B NH1 1 
ATOM   3759  N NH2 . ARG B 2 154 ? 137.455 116.000 109.008 1.00 23.17  ? 129 ARG B NH2 1 
ATOM   3760  N N   . ILE B 2 155 ? 130.097 115.216 107.140 1.00 15.21  ? 130 ILE B N   1 
ATOM   3761  C CA  . ILE B 2 155 ? 129.212 116.316 107.491 1.00 16.16  ? 130 ILE B CA  1 
ATOM   3762  C C   . ILE B 2 155 ? 129.169 116.439 109.003 1.00 16.97  ? 130 ILE B C   1 
ATOM   3763  O O   . ILE B 2 155 ? 129.062 115.434 109.713 1.00 23.81  ? 130 ILE B O   1 
ATOM   3764  C CB  . ILE B 2 155 ? 127.794 116.092 106.925 1.00 14.58  ? 130 ILE B CB  1 
ATOM   3765  C CG1 . ILE B 2 155 ? 127.838 115.959 105.404 1.00 13.86  ? 130 ILE B CG1 1 
ATOM   3766  C CG2 . ILE B 2 155 ? 126.868 117.221 107.331 1.00 17.20  ? 130 ILE B CG2 1 
ATOM   3767  C CD1 . ILE B 2 155 ? 126.530 115.521 104.802 1.00 15.58  ? 130 ILE B CD1 1 
ATOM   3768  N N   . THR B 2 156 ? 129.249 117.666 109.496 1.00 15.30  ? 131 THR B N   1 
ATOM   3769  C CA  . THR B 2 156 ? 128.942 117.959 110.887 1.00 17.78  ? 131 THR B CA  1 
ATOM   3770  C C   . THR B 2 156 ? 127.688 118.817 110.864 1.00 22.82  ? 131 THR B C   1 
ATOM   3771  O O   . THR B 2 156 ? 127.715 119.950 110.375 1.00 24.54  ? 131 THR B O   1 
ATOM   3772  C CB  . THR B 2 156 ? 130.098 118.674 111.580 1.00 21.73  ? 131 THR B CB  1 
ATOM   3773  O OG1 . THR B 2 156 ? 131.197 117.770 111.731 1.00 28.41  ? 131 THR B OG1 1 
ATOM   3774  C CG2 . THR B 2 156 ? 129.669 119.165 112.953 1.00 22.96  ? 131 THR B CG2 1 
ATOM   3775  N N   . THR B 2 157 ? 126.594 118.277 111.388 1.00 26.75  ? 132 THR B N   1 
ATOM   3776  C CA  . THR B 2 157 ? 125.299 118.935 111.321 1.00 24.10  ? 132 THR B CA  1 
ATOM   3777  C C   . THR B 2 157 ? 124.724 119.076 112.720 1.00 24.93  ? 132 THR B C   1 
ATOM   3778  O O   . THR B 2 157 ? 124.713 118.114 113.494 1.00 25.13  ? 132 THR B O   1 
ATOM   3779  C CB  . THR B 2 157 ? 124.328 118.163 110.414 1.00 21.36  ? 132 THR B CB  1 
ATOM   3780  O OG1 . THR B 2 157 ? 123.009 118.704 110.545 1.00 25.06  ? 132 THR B OG1 1 
ATOM   3781  C CG2 . THR B 2 157 ? 124.307 116.684 110.762 1.00 22.07  ? 132 THR B CG2 1 
ATOM   3782  N N   . THR B 2 158 ? 124.269 120.280 113.047 1.00 24.91  ? 133 THR B N   1 
ATOM   3783  C CA  . THR B 2 158 ? 123.494 120.508 114.257 1.00 26.08  ? 133 THR B CA  1 
ATOM   3784  C C   . THR B 2 158 ? 122.027 120.332 113.891 1.00 27.72  ? 133 THR B C   1 
ATOM   3785  O O   . THR B 2 158 ? 121.471 121.133 113.133 1.00 29.79  ? 133 THR B O   1 
ATOM   3786  C CB  . THR B 2 158 ? 123.765 121.896 114.827 1.00 27.16  ? 133 THR B CB  1 
ATOM   3787  O OG1 . THR B 2 158 ? 125.168 122.043 115.077 1.00 30.46  ? 133 THR B OG1 1 
ATOM   3788  C CG2 . THR B 2 158 ? 123.011 122.085 116.126 1.00 29.40  ? 133 THR B CG2 1 
ATOM   3789  N N   . ALA B 2 159 ? 121.398 119.292 114.424 1.00 29.62  ? 134 ALA B N   1 
ATOM   3790  C CA  . ALA B 2 159 ? 120.045 118.927 114.040 1.00 29.50  ? 134 ALA B CA  1 
ATOM   3791  C C   . ALA B 2 159 ? 119.086 119.236 115.177 1.00 32.38  ? 134 ALA B C   1 
ATOM   3792  O O   . ALA B 2 159 ? 119.401 119.008 116.347 1.00 36.78  ? 134 ALA B O   1 
ATOM   3793  C CB  . ALA B 2 159 ? 119.960 117.444 113.670 1.00 26.15  ? 134 ALA B CB  1 
ATOM   3794  N N   . ALA B 2 160 ? 117.911 119.744 114.823 1.00 32.80  ? 135 ALA B N   1 
ATOM   3795  C CA  . ALA B 2 160 ? 116.904 120.081 115.818 1.00 34.08  ? 135 ALA B CA  1 
ATOM   3796  C C   . ALA B 2 160 ? 116.275 118.822 116.397 1.00 45.28  ? 135 ALA B C   1 
ATOM   3797  O O   . ALA B 2 160 ? 115.857 117.925 115.659 1.00 42.23  ? 135 ALA B O   1 
ATOM   3798  C CB  . ALA B 2 160 ? 115.831 120.972 115.200 1.00 32.76  ? 135 ALA B CB  1 
ATOM   3799  N N   . CYS B 2 161 ? 116.211 118.757 117.726 1.00 54.19  ? 136 CYS B N   1 
ATOM   3800  C CA  . CYS B 2 161 ? 115.616 117.633 118.445 1.00 54.13  ? 136 CYS B CA  1 
ATOM   3801  C C   . CYS B 2 161 ? 114.725 118.192 119.549 1.00 58.52  ? 136 CYS B C   1 
ATOM   3802  O O   . CYS B 2 161 ? 115.223 118.664 120.575 1.00 64.84  ? 136 CYS B O   1 
ATOM   3803  C CB  . CYS B 2 161 ? 116.680 116.705 119.026 1.00 50.10  ? 136 CYS B CB  1 
ATOM   3804  S SG  . CYS B 2 161 ? 115.984 115.350 120.013 1.00 82.72  ? 136 CYS B SG  1 
ATOM   3805  N N   . MET B 2 162 ? 113.412 118.143 119.340 1.00 57.52  ? 137 MET B N   1 
ATOM   3806  C CA  . MET B 2 162 ? 112.489 118.538 120.392 1.00 58.98  ? 137 MET B CA  1 
ATOM   3807  C C   . MET B 2 162 ? 112.563 117.537 121.535 1.00 60.48  ? 137 MET B C   1 
ATOM   3808  O O   . MET B 2 162 ? 112.503 116.323 121.319 1.00 59.42  ? 137 MET B O   1 
ATOM   3809  C CB  . MET B 2 162 ? 111.062 118.635 119.861 1.00 59.71  ? 137 MET B CB  1 
ATOM   3810  C CG  . MET B 2 162 ? 110.120 119.358 120.812 1.00 64.58  ? 137 MET B CG  1 
ATOM   3811  S SD  . MET B 2 162 ? 110.536 121.096 121.043 1.00 83.07  ? 137 MET B SD  1 
ATOM   3812  C CE  . MET B 2 162 ? 109.257 121.601 122.191 1.00 75.00  ? 137 MET B CE  1 
ATOM   3813  N N   . MET B 2 163 ? 112.693 118.049 122.753 1.00 59.39  ? 138 MET B N   1 
ATOM   3814  C CA  . MET B 2 163 ? 112.900 117.222 123.928 1.00 57.76  ? 138 MET B CA  1 
ATOM   3815  C C   . MET B 2 163 ? 111.799 117.488 124.941 1.00 59.32  ? 138 MET B C   1 
ATOM   3816  O O   . MET B 2 163 ? 111.426 118.640 125.182 1.00 62.02  ? 138 MET B O   1 
ATOM   3817  C CB  . MET B 2 163 ? 114.268 117.497 124.557 1.00 52.53  ? 138 MET B CB  1 
ATOM   3818  C CG  . MET B 2 163 ? 115.423 117.340 123.587 1.00 61.74  ? 138 MET B CG  1 
ATOM   3819  S SD  . MET B 2 163 ? 117.037 117.573 124.347 1.00 83.59  ? 138 MET B SD  1 
ATOM   3820  C CE  . MET B 2 163 ? 118.086 117.444 122.904 1.00 61.02  ? 138 MET B CE  1 
ATOM   3821  N N   . ASP B 2 164 ? 111.285 116.417 125.530 1.00 55.88  ? 139 ASP B N   1 
ATOM   3822  C CA  . ASP B 2 164 ? 110.294 116.503 126.595 1.00 54.57  ? 139 ASP B CA  1 
ATOM   3823  C C   . ASP B 2 164 ? 111.052 116.285 127.898 1.00 54.27  ? 139 ASP B C   1 
ATOM   3824  O O   . ASP B 2 164 ? 111.364 115.150 128.266 1.00 53.18  ? 139 ASP B O   1 
ATOM   3825  C CB  . ASP B 2 164 ? 109.184 115.476 126.395 1.00 59.48  ? 139 ASP B CB  1 
ATOM   3826  C CG  . ASP B 2 164 ? 108.135 115.524 127.489 1.00 56.36  ? 139 ASP B CG  1 
ATOM   3827  O OD1 . ASP B 2 164 ? 108.100 116.517 128.245 1.00 50.89  ? 139 ASP B OD1 1 
ATOM   3828  O OD2 . ASP B 2 164 ? 107.340 114.566 127.591 1.00 56.43  ? 139 ASP B OD2 1 
ATOM   3829  N N   . LEU B 2 165 ? 111.350 117.380 128.592 1.00 52.10  ? 140 LEU B N   1 
ATOM   3830  C CA  . LEU B 2 165 ? 112.216 117.352 129.760 1.00 49.81  ? 140 LEU B CA  1 
ATOM   3831  C C   . LEU B 2 165 ? 111.432 117.407 131.060 1.00 50.11  ? 140 LEU B C   1 
ATOM   3832  O O   . LEU B 2 165 ? 111.988 117.784 132.096 1.00 47.79  ? 140 LEU B O   1 
ATOM   3833  C CB  . LEU B 2 165 ? 113.223 118.498 129.696 1.00 44.55  ? 140 LEU B CB  1 
ATOM   3834  C CG  . LEU B 2 165 ? 114.207 118.370 128.535 1.00 51.67  ? 140 LEU B CG  1 
ATOM   3835  C CD1 . LEU B 2 165 ? 114.531 119.729 127.965 1.00 56.18  ? 140 LEU B CD1 1 
ATOM   3836  C CD2 . LEU B 2 165 ? 115.471 117.658 128.981 1.00 52.75  ? 140 LEU B CD2 1 
ATOM   3837  N N   . ARG B 2 166 ? 110.151 117.042 131.026 1.00 50.19  ? 141 ARG B N   1 
ATOM   3838  C CA  . ARG B 2 166 ? 109.359 117.035 132.248 1.00 43.40  ? 141 ARG B CA  1 
ATOM   3839  C C   . ARG B 2 166 ? 109.922 116.038 133.251 1.00 45.22  ? 141 ARG B C   1 
ATOM   3840  O O   . ARG B 2 166 ? 109.915 116.290 134.461 1.00 51.11  ? 141 ARG B O   1 
ATOM   3841  C CB  . ARG B 2 166 ? 107.899 116.719 131.924 1.00 48.24  ? 141 ARG B CB  1 
ATOM   3842  C CG  . ARG B 2 166 ? 107.199 117.814 131.139 1.00 48.48  ? 141 ARG B CG  1 
ATOM   3843  C CD  . ARG B 2 166 ? 105.691 117.642 131.168 1.00 57.96  ? 141 ARG B CD  1 
ATOM   3844  N NE  . ARG B 2 166 ? 105.156 117.312 129.852 1.00 59.76  ? 141 ARG B NE  1 
ATOM   3845  C CZ  . ARG B 2 166 ? 104.936 116.079 129.419 1.00 64.16  ? 141 ARG B CZ  1 
ATOM   3846  N NH1 . ARG B 2 166 ? 105.206 115.024 130.171 1.00 60.73  ? 141 ARG B NH1 1 
ATOM   3847  N NH2 . ARG B 2 166 ? 104.436 115.899 128.200 1.00 62.01  ? 141 ARG B NH2 1 
ATOM   3848  N N   . ARG B 2 167 ? 110.407 114.897 132.766 1.00 43.72  ? 142 ARG B N   1 
ATOM   3849  C CA  . ARG B 2 167 ? 110.948 113.850 133.618 1.00 44.77  ? 142 ARG B CA  1 
ATOM   3850  C C   . ARG B 2 167 ? 112.452 113.994 133.836 1.00 42.44  ? 142 ARG B C   1 
ATOM   3851  O O   . ARG B 2 167 ? 113.076 113.078 134.377 1.00 45.57  ? 142 ARG B O   1 
ATOM   3852  C CB  . ARG B 2 167 ? 110.643 112.491 132.984 1.00 46.18  ? 142 ARG B CB  1 
ATOM   3853  C CG  . ARG B 2 167 ? 109.160 112.256 132.736 1.00 48.31  ? 142 ARG B CG  1 
ATOM   3854  C CD  . ARG B 2 167 ? 108.908 110.959 131.979 1.00 53.78  ? 142 ARG B CD  1 
ATOM   3855  N NE  . ARG B 2 167 ? 108.922 109.770 132.820 1.00 60.01  ? 142 ARG B NE  1 
ATOM   3856  C CZ  . ARG B 2 167 ? 107.864 109.311 133.474 1.00 59.43  ? 142 ARG B CZ  1 
ATOM   3857  N NH1 . ARG B 2 167 ? 106.698 109.935 133.427 1.00 53.34  ? 142 ARG B NH1 1 
ATOM   3858  N NH2 . ARG B 2 167 ? 107.974 108.189 134.179 1.00 54.78  ? 142 ARG B NH2 1 
ATOM   3859  N N   . TYR B 2 168 ? 113.035 115.119 133.430 1.00 37.94  ? 143 TYR B N   1 
ATOM   3860  C CA  . TYR B 2 168 ? 114.453 115.383 133.647 1.00 35.65  ? 143 TYR B CA  1 
ATOM   3861  C C   . TYR B 2 168 ? 114.787 115.319 135.137 1.00 38.38  ? 143 TYR B C   1 
ATOM   3862  O O   . TYR B 2 168 ? 114.039 115.856 135.961 1.00 45.72  ? 143 TYR B O   1 
ATOM   3863  C CB  . TYR B 2 168 ? 114.816 116.755 133.074 1.00 37.27  ? 143 TYR B CB  1 
ATOM   3864  C CG  . TYR B 2 168 ? 116.269 117.150 133.200 1.00 33.21  ? 143 TYR B CG  1 
ATOM   3865  C CD1 . TYR B 2 168 ? 116.734 117.828 134.317 1.00 33.23  ? 143 TYR B CD1 1 
ATOM   3866  C CD2 . TYR B 2 168 ? 117.172 116.863 132.187 1.00 33.11  ? 143 TYR B CD2 1 
ATOM   3867  C CE1 . TYR B 2 168 ? 118.059 118.195 134.428 1.00 37.47  ? 143 TYR B CE1 1 
ATOM   3868  C CE2 . TYR B 2 168 ? 118.497 117.227 132.291 1.00 33.57  ? 143 TYR B CE2 1 
ATOM   3869  C CZ  . TYR B 2 168 ? 118.935 117.891 133.411 1.00 33.74  ? 143 TYR B CZ  1 
ATOM   3870  O OH  . TYR B 2 168 ? 120.256 118.254 133.514 1.00 36.51  ? 143 TYR B OH  1 
ATOM   3871  N N   . PRO B 2 169 ? 115.906 114.685 135.526 1.00 34.12  ? 144 PRO B N   1 
ATOM   3872  C CA  . PRO B 2 169 ? 116.961 114.072 134.716 1.00 30.58  ? 144 PRO B CA  1 
ATOM   3873  C C   . PRO B 2 169 ? 116.706 112.599 134.435 1.00 33.41  ? 144 PRO B C   1 
ATOM   3874  O O   . PRO B 2 169 ? 117.591 111.887 133.972 1.00 37.72  ? 144 PRO B O   1 
ATOM   3875  C CB  . PRO B 2 169 ? 118.196 114.281 135.589 1.00 31.68  ? 144 PRO B CB  1 
ATOM   3876  C CG  . PRO B 2 169 ? 117.665 114.075 136.980 1.00 30.78  ? 144 PRO B CG  1 
ATOM   3877  C CD  . PRO B 2 169 ? 116.231 114.587 136.960 1.00 36.47  ? 144 PRO B CD  1 
ATOM   3878  N N   . LEU B 2 170 ? 115.495 112.117 134.709 1.00 38.82  ? 145 LEU B N   1 
ATOM   3879  C CA  . LEU B 2 170 ? 115.133 110.720 134.508 1.00 37.62  ? 145 LEU B CA  1 
ATOM   3880  C C   . LEU B 2 170 ? 114.421 110.519 133.181 1.00 39.53  ? 145 LEU B C   1 
ATOM   3881  O O   . LEU B 2 170 ? 113.552 109.650 133.060 1.00 37.67  ? 145 LEU B O   1 
ATOM   3882  C CB  . LEU B 2 170 ? 114.254 110.231 135.657 1.00 33.84  ? 145 LEU B CB  1 
ATOM   3883  C CG  . LEU B 2 170 ? 114.836 110.317 137.063 1.00 35.59  ? 145 LEU B CG  1 
ATOM   3884  C CD1 . LEU B 2 170 ? 113.721 110.389 138.086 1.00 45.44  ? 145 LEU B CD1 1 
ATOM   3885  C CD2 . LEU B 2 170 ? 115.715 109.113 137.324 1.00 37.74  ? 145 LEU B CD2 1 
ATOM   3886  N N   . ASP B 2 171 ? 114.779 111.315 132.183 1.00 37.75  ? 146 ASP B N   1 
ATOM   3887  C CA  . ASP B 2 171 ? 114.069 111.370 130.919 1.00 39.84  ? 146 ASP B CA  1 
ATOM   3888  C C   . ASP B 2 171 ? 114.781 110.526 129.877 1.00 39.58  ? 146 ASP B C   1 
ATOM   3889  O O   . ASP B 2 171 ? 115.994 110.314 129.938 1.00 40.39  ? 146 ASP B O   1 
ATOM   3890  C CB  . ASP B 2 171 ? 113.960 112.807 130.409 1.00 41.89  ? 146 ASP B CB  1 
ATOM   3891  C CG  . ASP B 2 171 ? 115.312 113.469 130.250 1.00 43.61  ? 146 ASP B CG  1 
ATOM   3892  O OD1 . ASP B 2 171 ? 116.179 113.263 131.123 1.00 41.69  ? 146 ASP B OD1 1 
ATOM   3893  O OD2 . ASP B 2 171 ? 115.509 114.191 129.252 1.00 42.89  ? 146 ASP B OD2 1 
ATOM   3894  N N   . GLU B 2 172 ? 114.007 110.048 128.915 1.00 41.91  ? 147 GLU B N   1 
ATOM   3895  C CA  . GLU B 2 172 ? 114.530 109.346 127.757 1.00 41.40  ? 147 GLU B CA  1 
ATOM   3896  C C   . GLU B 2 172 ? 114.104 110.140 126.534 1.00 38.29  ? 147 GLU B C   1 
ATOM   3897  O O   . GLU B 2 172 ? 112.922 110.464 126.381 1.00 38.76  ? 147 GLU B O   1 
ATOM   3898  C CB  . GLU B 2 172 ? 114.015 107.906 127.700 1.00 46.95  ? 147 GLU B CB  1 
ATOM   3899  C CG  . GLU B 2 172 ? 114.567 107.087 126.551 1.00 48.33  ? 147 GLU B CG  1 
ATOM   3900  C CD  . GLU B 2 172 ? 114.019 105.675 126.534 1.00 63.56  ? 147 GLU B CD  1 
ATOM   3901  O OE1 . GLU B 2 172 ? 113.161 105.359 127.384 1.00 69.66  ? 147 GLU B OE1 1 
ATOM   3902  O OE2 . GLU B 2 172 ? 114.451 104.879 125.674 1.00 69.64  ? 147 GLU B OE2 1 
ATOM   3903  N N   . GLN B 2 173 ? 115.060 110.444 125.667 1.00 36.45  ? 148 GLN B N   1 
ATOM   3904  C CA  . GLN B 2 173 ? 114.816 111.290 124.514 1.00 35.46  ? 148 GLN B CA  1 
ATOM   3905  C C   . GLN B 2 173 ? 114.887 110.477 123.235 1.00 35.96  ? 148 GLN B C   1 
ATOM   3906  O O   . GLN B 2 173 ? 115.526 109.424 123.168 1.00 42.91  ? 148 GLN B O   1 
ATOM   3907  C CB  . GLN B 2 173 ? 115.827 112.440 124.450 1.00 35.71  ? 148 GLN B CB  1 
ATOM   3908  C CG  . GLN B 2 173 ? 115.876 113.314 125.692 1.00 40.48  ? 148 GLN B CG  1 
ATOM   3909  C CD  . GLN B 2 173 ? 114.552 113.989 125.990 1.00 49.13  ? 148 GLN B CD  1 
ATOM   3910  O OE1 . GLN B 2 173 ? 113.736 114.208 125.094 1.00 50.72  ? 148 GLN B OE1 1 
ATOM   3911  N NE2 . GLN B 2 173 ? 114.331 114.322 127.256 1.00 48.99  ? 148 GLN B NE2 1 
ATOM   3912  N N   . ASN B 2 174 ? 114.212 110.989 122.211 1.00 34.47  ? 149 ASN B N   1 
ATOM   3913  C CA  . ASN B 2 174 ? 114.157 110.354 120.902 1.00 37.18  ? 149 ASN B CA  1 
ATOM   3914  C C   . ASN B 2 174 ? 114.497 111.451 119.901 1.00 39.71  ? 149 ASN B C   1 
ATOM   3915  O O   . ASN B 2 174 ? 113.624 112.208 119.469 1.00 43.47  ? 149 ASN B O   1 
ATOM   3916  C CB  . ASN B 2 174 ? 112.772 109.741 120.670 1.00 41.23  ? 149 ASN B CB  1 
ATOM   3917  C CG  . ASN B 2 174 ? 112.545 109.274 119.243 1.00 45.44  ? 149 ASN B CG  1 
ATOM   3918  O OD1 . ASN B 2 174 ? 113.416 109.370 118.381 1.00 47.24  ? 149 ASN B OD1 1 
ATOM   3919  N ND2 . ASN B 2 174 ? 111.350 108.758 118.993 1.00 53.37  ? 149 ASN B ND2 1 
ATOM   3920  N N   . CYS B 2 175 ? 115.770 111.528 119.532 1.00 38.82  ? 150 CYS B N   1 
ATOM   3921  C CA  . CYS B 2 175 ? 116.238 112.484 118.544 1.00 39.52  ? 150 CYS B CA  1 
ATOM   3922  C C   . CYS B 2 175 ? 116.320 111.801 117.191 1.00 39.80  ? 150 CYS B C   1 
ATOM   3923  O O   . CYS B 2 175 ? 116.615 110.608 117.095 1.00 44.73  ? 150 CYS B O   1 
ATOM   3924  C CB  . CYS B 2 175 ? 117.595 113.077 118.925 1.00 41.73  ? 150 CYS B CB  1 
ATOM   3925  S SG  . CYS B 2 175 ? 117.538 114.099 120.402 1.00 74.28  ? 150 CYS B SG  1 
ATOM   3926  N N   . THR B 2 176 ? 116.059 112.572 116.143 1.00 39.22  ? 151 THR B N   1 
ATOM   3927  C CA  . THR B 2 176 ? 115.936 112.028 114.803 1.00 39.97  ? 151 THR B CA  1 
ATOM   3928  C C   . THR B 2 176 ? 116.750 112.862 113.828 1.00 34.47  ? 151 THR B C   1 
ATOM   3929  O O   . THR B 2 176 ? 117.243 113.946 114.149 1.00 40.81  ? 151 THR B O   1 
ATOM   3930  C CB  . THR B 2 176 ? 114.470 111.985 114.337 1.00 43.09  ? 151 THR B CB  1 
ATOM   3931  O OG1 . THR B 2 176 ? 114.007 113.317 114.089 1.00 50.11  ? 151 THR B OG1 1 
ATOM   3932  C CG2 . THR B 2 176 ? 113.577 111.331 115.376 1.00 34.08  ? 151 THR B CG2 1 
ATOM   3933  N N   . LEU B 2 177 ? 116.889 112.321 112.624 1.00 30.68  ? 152 LEU B N   1 
ATOM   3934  C CA  . LEU B 2 177 ? 117.469 113.027 111.491 1.00 33.78  ? 152 LEU B CA  1 
ATOM   3935  C C   . LEU B 2 177 ? 116.603 112.708 110.288 1.00 34.82  ? 152 LEU B C   1 
ATOM   3936  O O   . LEU B 2 177 ? 116.525 111.547 109.875 1.00 39.71  ? 152 LEU B O   1 
ATOM   3937  C CB  . LEU B 2 177 ? 118.918 112.602 111.246 1.00 34.39  ? 152 LEU B CB  1 
ATOM   3938  C CG  . LEU B 2 177 ? 119.654 113.268 110.083 1.00 29.59  ? 152 LEU B CG  1 
ATOM   3939  C CD1 . LEU B 2 177 ? 119.968 114.719 110.398 1.00 27.44  ? 152 LEU B CD1 1 
ATOM   3940  C CD2 . LEU B 2 177 ? 120.919 112.501 109.747 1.00 24.40  ? 152 LEU B CD2 1 
ATOM   3941  N N   . GLU B 2 178 ? 115.962 113.722 109.725 1.00 30.71  ? 153 GLU B N   1 
ATOM   3942  C CA  . GLU B 2 178 ? 115.020 113.526 108.634 1.00 32.09  ? 153 GLU B CA  1 
ATOM   3943  C C   . GLU B 2 178 ? 115.710 113.867 107.324 1.00 31.94  ? 153 GLU B C   1 
ATOM   3944  O O   . GLU B 2 178 ? 116.234 114.973 107.160 1.00 35.88  ? 153 GLU B O   1 
ATOM   3945  C CB  . GLU B 2 178 ? 113.773 114.388 108.828 1.00 39.74  ? 153 GLU B CB  1 
ATOM   3946  C CG  . GLU B 2 178 ? 113.122 114.245 110.192 1.00 42.75  ? 153 GLU B CG  1 
ATOM   3947  C CD  . GLU B 2 178 ? 112.580 112.851 110.432 1.00 43.39  ? 153 GLU B CD  1 
ATOM   3948  O OE1 . GLU B 2 178 ? 112.168 112.197 109.450 1.00 43.74  ? 153 GLU B OE1 1 
ATOM   3949  O OE2 . GLU B 2 178 ? 112.568 112.407 111.598 1.00 42.86  ? 153 GLU B OE2 1 
ATOM   3950  N N   . ILE B 2 179 ? 115.701 112.919 106.395 1.00 32.11  ? 154 ILE B N   1 
ATOM   3951  C CA  . ILE B 2 179 ? 116.394 113.052 105.123 1.00 33.18  ? 154 ILE B CA  1 
ATOM   3952  C C   . ILE B 2 179 ? 115.335 113.080 104.033 1.00 36.67  ? 154 ILE B C   1 
ATOM   3953  O O   . ILE B 2 179 ? 114.538 112.142 103.906 1.00 47.21  ? 154 ILE B O   1 
ATOM   3954  C CB  . ILE B 2 179 ? 117.389 111.901 104.913 1.00 28.90  ? 154 ILE B CB  1 
ATOM   3955  C CG1 . ILE B 2 179 ? 118.379 111.841 106.077 1.00 23.79  ? 154 ILE B CG1 1 
ATOM   3956  C CG2 . ILE B 2 179 ? 118.106 112.042 103.596 1.00 29.30  ? 154 ILE B CG2 1 
ATOM   3957  C CD1 . ILE B 2 179 ? 119.121 110.532 106.185 1.00 21.79  ? 154 ILE B CD1 1 
ATOM   3958  N N   . GLU B 2 180 ? 115.334 114.146 103.239 1.00 30.45  ? 155 GLU B N   1 
ATOM   3959  C CA  . GLU B 2 180 ? 114.281 114.374 102.264 1.00 32.56  ? 155 GLU B CA  1 
ATOM   3960  C C   . GLU B 2 180 ? 114.881 114.991 101.010 1.00 33.77  ? 155 GLU B C   1 
ATOM   3961  O O   . GLU B 2 180 ? 115.975 115.556 101.034 1.00 33.65  ? 155 GLU B O   1 
ATOM   3962  C CB  . GLU B 2 180 ? 113.181 115.282 102.838 1.00 34.82  ? 155 GLU B CB  1 
ATOM   3963  C CG  . GLU B 2 180 ? 111.892 115.313 102.027 1.00 41.54  ? 155 GLU B CG  1 
ATOM   3964  C CD  . GLU B 2 180 ? 110.659 115.486 102.889 1.00 49.18  ? 155 GLU B CD  1 
ATOM   3965  O OE1 . GLU B 2 180 ? 110.609 114.889 103.984 1.00 58.63  ? 155 GLU B OE1 1 
ATOM   3966  O OE2 . GLU B 2 180 ? 109.738 116.217 102.469 1.00 51.75  ? 155 GLU B OE2 1 
ATOM   3967  N N   . SER B 2 181 ? 114.146 114.878 99.909  1.00 38.97  ? 156 SER B N   1 
ATOM   3968  C CA  . SER B 2 181 ? 114.524 115.524 98.664  1.00 44.51  ? 156 SER B CA  1 
ATOM   3969  C C   . SER B 2 181 ? 113.828 116.875 98.621  1.00 47.98  ? 156 SER B C   1 
ATOM   3970  O O   . SER B 2 181 ? 112.606 116.953 98.786  1.00 49.84  ? 156 SER B O   1 
ATOM   3971  C CB  . SER B 2 181 ? 114.132 114.673 97.456  1.00 50.66  ? 156 SER B CB  1 
ATOM   3972  O OG  . SER B 2 181 ? 114.626 115.238 96.254  1.00 55.48  ? 156 SER B OG  1 
ATOM   3973  N N   . TYR B 2 182 ? 114.605 117.938 98.411  1.00 44.55  ? 157 TYR B N   1 
ATOM   3974  C CA  . TYR B 2 182 ? 114.030 119.277 98.456  1.00 40.24  ? 157 TYR B CA  1 
ATOM   3975  C C   . TYR B 2 182 ? 113.020 119.489 97.335  1.00 43.33  ? 157 TYR B C   1 
ATOM   3976  O O   . TYR B 2 182 ? 111.939 120.042 97.565  1.00 48.78  ? 157 TYR B O   1 
ATOM   3977  C CB  . TYR B 2 182 ? 115.136 120.330 98.401  1.00 40.42  ? 157 TYR B CB  1 
ATOM   3978  C CG  . TYR B 2 182 ? 114.654 121.710 98.774  1.00 41.76  ? 157 TYR B CG  1 
ATOM   3979  C CD1 . TYR B 2 182 ? 114.117 122.566 97.826  1.00 39.20  ? 157 TYR B CD1 1 
ATOM   3980  C CD2 . TYR B 2 182 ? 114.723 122.148 100.088 1.00 34.42  ? 157 TYR B CD2 1 
ATOM   3981  C CE1 . TYR B 2 182 ? 113.668 123.820 98.178  1.00 37.74  ? 157 TYR B CE1 1 
ATOM   3982  C CE2 . TYR B 2 182 ? 114.279 123.397 100.447 1.00 33.20  ? 157 TYR B CE2 1 
ATOM   3983  C CZ  . TYR B 2 182 ? 113.752 124.229 99.490  1.00 45.76  ? 157 TYR B CZ  1 
ATOM   3984  O OH  . TYR B 2 182 ? 113.308 125.479 99.846  1.00 73.16  ? 157 TYR B OH  1 
ATOM   3985  N N   . GLY B 2 183 ? 113.349 119.060 96.121  1.00 45.63  ? 158 GLY B N   1 
ATOM   3986  C CA  . GLY B 2 183 ? 112.532 119.398 94.973  1.00 53.49  ? 158 GLY B CA  1 
ATOM   3987  C C   . GLY B 2 183 ? 111.714 118.251 94.417  1.00 60.47  ? 158 GLY B C   1 
ATOM   3988  O O   . GLY B 2 183 ? 110.564 118.443 94.013  1.00 63.07  ? 158 GLY B O   1 
ATOM   3989  N N   . TYR B 2 184 ? 112.292 117.056 94.386  1.00 63.80  ? 159 TYR B N   1 
ATOM   3990  C CA  . TYR B 2 184 ? 111.688 115.963 93.645  1.00 67.72  ? 159 TYR B CA  1 
ATOM   3991  C C   . TYR B 2 184 ? 110.638 115.251 94.494  1.00 72.76  ? 159 TYR B C   1 
ATOM   3992  O O   . TYR B 2 184 ? 110.617 115.352 95.724  1.00 69.58  ? 159 TYR B O   1 
ATOM   3993  C CB  . TYR B 2 184 ? 112.752 114.966 93.191  1.00 63.83  ? 159 TYR B CB  1 
ATOM   3994  C CG  . TYR B 2 184 ? 113.779 115.538 92.245  1.00 62.26  ? 159 TYR B CG  1 
ATOM   3995  C CD1 . TYR B 2 184 ? 113.463 115.804 90.921  1.00 65.82  ? 159 TYR B CD1 1 
ATOM   3996  C CD2 . TYR B 2 184 ? 115.069 115.807 92.677  1.00 60.91  ? 159 TYR B CD2 1 
ATOM   3997  C CE1 . TYR B 2 184 ? 114.403 116.325 90.056  1.00 69.86  ? 159 TYR B CE1 1 
ATOM   3998  C CE2 . TYR B 2 184 ? 116.014 116.328 91.821  1.00 65.72  ? 159 TYR B CE2 1 
ATOM   3999  C CZ  . TYR B 2 184 ? 115.678 116.585 90.512  1.00 70.92  ? 159 TYR B CZ  1 
ATOM   4000  O OH  . TYR B 2 184 ? 116.622 117.104 89.657  1.00 72.96  ? 159 TYR B OH  1 
ATOM   4001  N N   . THR B 2 185 ? 109.767 114.511 93.816  1.00 78.00  ? 160 THR B N   1 
ATOM   4002  C CA  . THR B 2 185 ? 108.784 113.646 94.450  1.00 80.46  ? 160 THR B CA  1 
ATOM   4003  C C   . THR B 2 185 ? 109.139 112.185 94.184  1.00 77.36  ? 160 THR B C   1 
ATOM   4004  O O   . THR B 2 185 ? 110.078 111.873 93.447  1.00 74.85  ? 160 THR B O   1 
ATOM   4005  C CB  . THR B 2 185 ? 107.376 113.972 93.950  1.00 79.01  ? 160 THR B CB  1 
ATOM   4006  O OG1 . THR B 2 185 ? 107.282 113.678 92.551  1.00 81.86  ? 160 THR B OG1 1 
ATOM   4007  C CG2 . THR B 2 185 ? 107.061 115.443 94.174  1.00 74.64  ? 160 THR B CG2 1 
ATOM   4008  N N   . THR B 2 186 ? 108.368 111.281 94.797  1.00 74.16  ? 161 THR B N   1 
ATOM   4009  C CA  . THR B 2 186 ? 108.631 109.855 94.635  1.00 75.44  ? 161 THR B CA  1 
ATOM   4010  C C   . THR B 2 186 ? 108.426 109.385 93.201  1.00 78.75  ? 161 THR B C   1 
ATOM   4011  O O   . THR B 2 186 ? 108.874 108.289 92.850  1.00 75.39  ? 161 THR B O   1 
ATOM   4012  C CB  . THR B 2 186 ? 107.742 109.041 95.574  1.00 75.21  ? 161 THR B CB  1 
ATOM   4013  O OG1 . THR B 2 186 ? 106.365 109.318 95.289  1.00 89.07  ? 161 THR B OG1 1 
ATOM   4014  C CG2 . THR B 2 186 ? 108.036 109.389 97.022  1.00 68.48  ? 161 THR B CG2 1 
ATOM   4015  N N   . ASP B 2 187 ? 107.757 110.185 92.369  1.00 82.56  ? 162 ASP B N   1 
ATOM   4016  C CA  . ASP B 2 187 ? 107.675 109.882 90.946  1.00 86.62  ? 162 ASP B CA  1 
ATOM   4017  C C   . ASP B 2 187 ? 109.017 110.054 90.249  1.00 83.79  ? 162 ASP B C   1 
ATOM   4018  O O   . ASP B 2 187 ? 109.210 109.510 89.156  1.00 84.30  ? 162 ASP B O   1 
ATOM   4019  C CB  . ASP B 2 187 ? 106.620 110.762 90.273  1.00 93.20  ? 162 ASP B CB  1 
ATOM   4020  C CG  . ASP B 2 187 ? 105.240 110.582 90.874  1.00 87.05  ? 162 ASP B CG  1 
ATOM   4021  O OD1 . ASP B 2 187 ? 104.922 109.456 91.312  1.00 80.84  ? 162 ASP B OD1 1 
ATOM   4022  O OD2 . ASP B 2 187 ? 104.470 111.564 90.902  1.00 79.62  ? 162 ASP B OD2 1 
ATOM   4023  N N   . ASP B 2 188 ? 109.942 110.792 90.857  1.00 81.50  ? 163 ASP B N   1 
ATOM   4024  C CA  . ASP B 2 188 ? 111.251 111.079 90.282  1.00 83.27  ? 163 ASP B CA  1 
ATOM   4025  C C   . ASP B 2 188 ? 112.394 110.399 91.015  1.00 81.59  ? 163 ASP B C   1 
ATOM   4026  O O   . ASP B 2 188 ? 113.296 109.861 90.368  1.00 82.94  ? 163 ASP B O   1 
ATOM   4027  C CB  . ASP B 2 188 ? 111.496 112.592 90.258  1.00 85.19  ? 163 ASP B CB  1 
ATOM   4028  C CG  . ASP B 2 188 ? 110.652 113.301 89.216  1.00 86.67  ? 163 ASP B CG  1 
ATOM   4029  O OD1 . ASP B 2 188 ? 110.512 112.761 88.099  1.00 90.26  ? 163 ASP B OD1 1 
ATOM   4030  O OD2 . ASP B 2 188 ? 110.130 114.397 89.511  1.00 79.35  ? 163 ASP B OD2 1 
ATOM   4031  N N   . ILE B 2 189 ? 112.399 110.423 92.345  1.00 76.86  ? 164 ILE B N   1 
ATOM   4032  C CA  . ILE B 2 189 ? 113.514 109.912 93.133  1.00 73.08  ? 164 ILE B CA  1 
ATOM   4033  C C   . ILE B 2 189 ? 112.947 109.148 94.322  1.00 70.03  ? 164 ILE B C   1 
ATOM   4034  O O   . ILE B 2 189 ? 111.963 109.572 94.937  1.00 74.98  ? 164 ILE B O   1 
ATOM   4035  C CB  . ILE B 2 189 ? 114.459 111.046 93.587  1.00 72.35  ? 164 ILE B CB  1 
ATOM   4036  C CG1 . ILE B 2 189 ? 115.741 110.478 94.189  1.00 66.10  ? 164 ILE B CG1 1 
ATOM   4037  C CG2 . ILE B 2 189 ? 113.785 111.948 94.601  1.00 71.84  ? 164 ILE B CG2 1 
ATOM   4038  C CD1 . ILE B 2 189 ? 116.755 111.542 94.542  1.00 59.79  ? 164 ILE B CD1 1 
ATOM   4039  N N   . GLU B 2 190 ? 113.542 107.995 94.618  1.00 71.45  ? 165 GLU B N   1 
ATOM   4040  C CA  . GLU B 2 190 ? 113.126 107.172 95.743  1.00 67.45  ? 165 GLU B CA  1 
ATOM   4041  C C   . GLU B 2 190 ? 114.323 106.863 96.628  1.00 60.39  ? 165 GLU B C   1 
ATOM   4042  O O   . GLU B 2 190 ? 115.410 106.554 96.132  1.00 61.48  ? 165 GLU B O   1 
ATOM   4043  C CB  . GLU B 2 190 ? 112.490 105.864 95.267  1.00 70.80  ? 165 GLU B CB  1 
ATOM   4044  C CG  . GLU B 2 190 ? 111.215 106.045 94.470  1.00 78.95  ? 165 GLU B CG  1 
ATOM   4045  C CD  . GLU B 2 190 ? 110.553 104.725 94.137  1.00 86.93  ? 165 GLU B CD  1 
ATOM   4046  O OE1 . GLU B 2 190 ? 111.214 103.675 94.284  1.00 82.59  ? 165 GLU B OE1 1 
ATOM   4047  O OE2 . GLU B 2 190 ? 109.373 104.737 93.726  1.00 88.84  ? 165 GLU B OE2 1 
ATOM   4048  N N   . PHE B 2 191 ? 114.118 106.945 97.937  1.00 50.84  ? 166 PHE B N   1 
ATOM   4049  C CA  . PHE B 2 191 ? 115.168 106.674 98.904  1.00 47.87  ? 166 PHE B CA  1 
ATOM   4050  C C   . PHE B 2 191 ? 114.977 105.296 99.524  1.00 51.66  ? 166 PHE B C   1 
ATOM   4051  O O   . PHE B 2 191 ? 113.852 104.812 99.672  1.00 56.04  ? 166 PHE B O   1 
ATOM   4052  C CB  . PHE B 2 191 ? 115.185 107.733 100.008 1.00 46.26  ? 166 PHE B CB  1 
ATOM   4053  C CG  . PHE B 2 191 ? 115.620 109.096 99.549  1.00 47.74  ? 166 PHE B CG  1 
ATOM   4054  C CD1 . PHE B 2 191 ? 116.177 109.283 98.296  1.00 52.23  ? 166 PHE B CD1 1 
ATOM   4055  C CD2 . PHE B 2 191 ? 115.487 110.191 100.386 1.00 42.27  ? 166 PHE B CD2 1 
ATOM   4056  C CE1 . PHE B 2 191 ? 116.578 110.537 97.882  1.00 49.97  ? 166 PHE B CE1 1 
ATOM   4057  C CE2 . PHE B 2 191 ? 115.889 111.446 99.977  1.00 43.26  ? 166 PHE B CE2 1 
ATOM   4058  C CZ  . PHE B 2 191 ? 116.436 111.619 98.723  1.00 46.02  ? 166 PHE B CZ  1 
ATOM   4059  N N   . TYR B 2 192 ? 116.092 104.664 99.884  1.00 52.77  ? 167 TYR B N   1 
ATOM   4060  C CA  . TYR B 2 192 ? 116.060 103.440 100.671 1.00 46.68  ? 167 TYR B CA  1 
ATOM   4061  C C   . TYR B 2 192 ? 117.371 103.305 101.430 1.00 45.06  ? 167 TYR B C   1 
ATOM   4062  O O   . TYR B 2 192 ? 118.397 103.867 101.041 1.00 49.80  ? 167 TYR B O   1 
ATOM   4063  C CB  . TYR B 2 192 ? 115.804 102.206 99.795  1.00 45.01  ? 167 TYR B CB  1 
ATOM   4064  C CG  . TYR B 2 192 ? 116.920 101.868 98.830  1.00 51.38  ? 167 TYR B CG  1 
ATOM   4065  C CD1 . TYR B 2 192 ? 116.969 102.447 97.569  1.00 56.78  ? 167 TYR B CD1 1 
ATOM   4066  C CD2 . TYR B 2 192 ? 117.918 100.966 99.175  1.00 50.16  ? 167 TYR B CD2 1 
ATOM   4067  C CE1 . TYR B 2 192 ? 117.981 102.139 96.680  1.00 59.64  ? 167 TYR B CE1 1 
ATOM   4068  C CE2 . TYR B 2 192 ? 118.936 100.654 98.293  1.00 50.66  ? 167 TYR B CE2 1 
ATOM   4069  C CZ  . TYR B 2 192 ? 118.961 101.242 97.047  1.00 56.84  ? 167 TYR B CZ  1 
ATOM   4070  O OH  . TYR B 2 192 ? 119.971 100.938 96.164  1.00 54.39  ? 167 TYR B OH  1 
ATOM   4071  N N   . TRP B 2 193 ? 117.326 102.543 102.520 1.00 41.44  ? 168 TRP B N   1 
ATOM   4072  C CA  . TRP B 2 193 ? 118.516 102.269 103.316 1.00 42.45  ? 168 TRP B CA  1 
ATOM   4073  C C   . TRP B 2 193 ? 119.296 101.110 102.708 1.00 45.12  ? 168 TRP B C   1 
ATOM   4074  O O   . TRP B 2 193 ? 118.801 99.980  102.654 1.00 47.52  ? 168 TRP B O   1 
ATOM   4075  C CB  . TRP B 2 193 ? 118.132 101.960 104.760 1.00 39.81  ? 168 TRP B CB  1 
ATOM   4076  C CG  . TRP B 2 193 ? 117.732 103.166 105.541 1.00 39.20  ? 168 TRP B CG  1 
ATOM   4077  C CD1 . TRP B 2 193 ? 116.481 103.480 105.976 1.00 45.31  ? 168 TRP B CD1 1 
ATOM   4078  C CD2 . TRP B 2 193 ? 118.590 104.219 105.995 1.00 40.29  ? 168 TRP B CD2 1 
ATOM   4079  N NE1 . TRP B 2 193 ? 116.503 104.667 106.666 1.00 45.37  ? 168 TRP B NE1 1 
ATOM   4080  C CE2 . TRP B 2 193 ? 117.788 105.140 106.692 1.00 42.06  ? 168 TRP B CE2 1 
ATOM   4081  C CE3 . TRP B 2 193 ? 119.958 104.473 105.876 1.00 38.83  ? 168 TRP B CE3 1 
ATOM   4082  C CZ2 . TRP B 2 193 ? 118.307 106.295 107.268 1.00 36.34  ? 168 TRP B CZ2 1 
ATOM   4083  C CZ3 . TRP B 2 193 ? 120.472 105.621 106.450 1.00 35.37  ? 168 TRP B CZ3 1 
ATOM   4084  C CH2 . TRP B 2 193 ? 119.648 106.517 107.136 1.00 31.42  ? 168 TRP B CH2 1 
ATOM   4085  N N   . ARG B 2 194 ? 120.510 101.391 102.243 1.00 42.32  ? 169 ARG B N   1 
ATOM   4086  C CA  . ARG B 2 194 ? 121.327 100.373 101.596 1.00 41.56  ? 169 ARG B CA  1 
ATOM   4087  C C   . ARG B 2 194 ? 121.894 99.419  102.640 1.00 48.33  ? 169 ARG B C   1 
ATOM   4088  O O   . ARG B 2 194 ? 122.700 99.823  103.485 1.00 45.52  ? 169 ARG B O   1 
ATOM   4089  C CB  . ARG B 2 194 ? 122.453 101.030 100.806 1.00 43.06  ? 169 ARG B CB  1 
ATOM   4090  C CG  . ARG B 2 194 ? 123.130 100.110 99.812  1.00 47.00  ? 169 ARG B CG  1 
ATOM   4091  C CD  . ARG B 2 194 ? 124.034 100.892 98.885  1.00 42.55  ? 169 ARG B CD  1 
ATOM   4092  N NE  . ARG B 2 194 ? 124.605 100.058 97.836  1.00 42.76  ? 169 ARG B NE  1 
ATOM   4093  C CZ  . ARG B 2 194 ? 125.735 99.375  97.956  1.00 47.33  ? 169 ARG B CZ  1 
ATOM   4094  N NH1 . ARG B 2 194 ? 126.433 99.386  99.079  1.00 45.94  ? 169 ARG B NH1 1 
ATOM   4095  N NH2 . ARG B 2 194 ? 126.174 98.661  96.923  1.00 48.95  ? 169 ARG B NH2 1 
ATOM   4096  N N   . GLY B 2 195 ? 121.482 98.157  102.582 1.00 55.34  ? 170 GLY B N   1 
ATOM   4097  C CA  . GLY B 2 195 ? 121.840 97.186  103.593 1.00 51.26  ? 170 GLY B CA  1 
ATOM   4098  C C   . GLY B 2 195 ? 120.838 96.986  104.708 1.00 52.61  ? 170 GLY B C   1 
ATOM   4099  O O   . GLY B 2 195 ? 121.180 96.350  105.712 1.00 51.89  ? 170 GLY B O   1 
ATOM   4100  N N   . GLY B 2 196 ? 119.618 97.495  104.563 1.00 57.64  ? 171 GLY B N   1 
ATOM   4101  C CA  . GLY B 2 196 ? 118.607 97.318  105.594 1.00 53.70  ? 171 GLY B CA  1 
ATOM   4102  C C   . GLY B 2 196 ? 119.031 97.926  106.916 1.00 54.86  ? 171 GLY B C   1 
ATOM   4103  O O   . GLY B 2 196 ? 119.478 99.075  106.982 1.00 59.09  ? 171 GLY B O   1 
ATOM   4104  N N   . ASP B 2 197 ? 118.900 97.145  107.990 1.00 53.87  ? 172 ASP B N   1 
ATOM   4105  C CA  . ASP B 2 197 ? 119.256 97.632  109.317 1.00 55.59  ? 172 ASP B CA  1 
ATOM   4106  C C   . ASP B 2 197 ? 120.759 97.740  109.529 1.00 57.70  ? 172 ASP B C   1 
ATOM   4107  O O   . ASP B 2 197 ? 121.183 98.291  110.550 1.00 58.29  ? 172 ASP B O   1 
ATOM   4108  C CB  . ASP B 2 197 ? 118.656 96.724  110.390 1.00 61.60  ? 172 ASP B CB  1 
ATOM   4109  C CG  . ASP B 2 197 ? 117.159 96.905  110.537 1.00 79.32  ? 172 ASP B CG  1 
ATOM   4110  O OD1 . ASP B 2 197 ? 116.678 98.044  110.364 1.00 79.15  ? 172 ASP B OD1 1 
ATOM   4111  O OD2 . ASP B 2 197 ? 116.463 95.910  110.829 1.00 82.44  ? 172 ASP B OD2 1 
ATOM   4112  N N   . LYS B 2 198 ? 121.568 97.234  108.603 1.00 54.03  ? 173 LYS B N   1 
ATOM   4113  C CA  . LYS B 2 198 ? 123.011 97.412  108.641 1.00 48.77  ? 173 LYS B CA  1 
ATOM   4114  C C   . LYS B 2 198 ? 123.466 98.678  107.930 1.00 42.90  ? 173 LYS B C   1 
ATOM   4115  O O   . LYS B 2 198 ? 124.674 98.893  107.790 1.00 43.28  ? 173 LYS B O   1 
ATOM   4116  C CB  . LYS B 2 198 ? 123.713 96.192  108.039 1.00 55.90  ? 173 LYS B CB  1 
ATOM   4117  C CG  . LYS B 2 198 ? 123.321 94.873  108.684 1.00 63.15  ? 173 LYS B CG  1 
ATOM   4118  C CD  . LYS B 2 198 ? 124.125 93.721  108.107 1.00 70.04  ? 173 LYS B CD  1 
ATOM   4119  C CE  . LYS B 2 198 ? 123.685 92.390  108.694 1.00 77.96  ? 173 LYS B CE  1 
ATOM   4120  N NZ  . LYS B 2 198 ? 123.804 92.373  110.179 1.00 77.59  ? 173 LYS B NZ  1 
ATOM   4121  N N   . ALA B 2 199 ? 122.530 99.510  107.468 1.00 41.74  ? 174 ALA B N   1 
ATOM   4122  C CA  . ALA B 2 199 ? 122.909 100.705 106.722 1.00 42.59  ? 174 ALA B CA  1 
ATOM   4123  C C   . ALA B 2 199 ? 123.704 101.671 107.590 1.00 42.75  ? 174 ALA B C   1 
ATOM   4124  O O   . ALA B 2 199 ? 124.721 102.217 107.151 1.00 45.69  ? 174 ALA B O   1 
ATOM   4125  C CB  . ALA B 2 199 ? 121.664 101.387 106.158 1.00 37.59  ? 174 ALA B CB  1 
ATOM   4126  N N   . VAL B 2 200 ? 123.284 101.872 108.834 1.00 36.82  ? 175 VAL B N   1 
ATOM   4127  C CA  . VAL B 2 200 ? 123.948 102.804 109.736 1.00 31.62  ? 175 VAL B CA  1 
ATOM   4128  C C   . VAL B 2 200 ? 124.909 102.018 110.611 1.00 35.72  ? 175 VAL B C   1 
ATOM   4129  O O   . VAL B 2 200 ? 124.533 100.996 111.198 1.00 41.66  ? 175 VAL B O   1 
ATOM   4130  C CB  . VAL B 2 200 ? 122.935 103.587 110.585 1.00 32.62  ? 175 VAL B CB  1 
ATOM   4131  C CG1 . VAL B 2 200 ? 123.660 104.506 111.550 1.00 33.10  ? 175 VAL B CG1 1 
ATOM   4132  C CG2 . VAL B 2 200 ? 122.033 104.400 109.686 1.00 34.97  ? 175 VAL B CG2 1 
ATOM   4133  N N   . THR B 2 201 ? 126.148 102.493 110.701 1.00 37.95  ? 176 THR B N   1 
ATOM   4134  C CA  . THR B 2 201 ? 127.180 101.840 111.488 1.00 40.18  ? 176 THR B CA  1 
ATOM   4135  C C   . THR B 2 201 ? 127.860 102.870 112.377 1.00 39.21  ? 176 THR B C   1 
ATOM   4136  O O   . THR B 2 201 ? 127.712 104.081 112.197 1.00 39.91  ? 176 THR B O   1 
ATOM   4137  C CB  . THR B 2 201 ? 128.217 101.152 110.588 1.00 37.41  ? 176 THR B CB  1 
ATOM   4138  O OG1 . THR B 2 201 ? 127.613 100.806 109.336 1.00 34.16  ? 176 THR B OG1 1 
ATOM   4139  C CG2 . THR B 2 201 ? 128.744 99.888  111.248 1.00 42.70  ? 176 THR B CG2 1 
ATOM   4140  N N   . GLY B 2 202 ? 128.605 102.370 113.355 1.00 43.99  ? 177 GLY B N   1 
ATOM   4141  C CA  . GLY B 2 202 ? 129.338 103.210 114.272 1.00 45.02  ? 177 GLY B CA  1 
ATOM   4142  C C   . GLY B 2 202 ? 128.556 103.627 115.493 1.00 50.49  ? 177 GLY B C   1 
ATOM   4143  O O   . GLY B 2 202 ? 129.106 104.331 116.349 1.00 48.48  ? 177 GLY B O   1 
ATOM   4144  N N   . VAL B 2 203 ? 127.289 103.222 115.597 1.00 56.58  ? 178 VAL B N   1 
ATOM   4145  C CA  . VAL B 2 203 ? 126.479 103.600 116.749 1.00 58.67  ? 178 VAL B CA  1 
ATOM   4146  C C   . VAL B 2 203 ? 127.035 102.976 118.022 1.00 61.61  ? 178 VAL B C   1 
ATOM   4147  O O   . VAL B 2 203 ? 127.122 103.635 119.065 1.00 60.43  ? 178 VAL B O   1 
ATOM   4148  C CB  . VAL B 2 203 ? 125.011 103.207 116.514 1.00 55.85  ? 178 VAL B CB  1 
ATOM   4149  C CG1 . VAL B 2 203 ? 124.176 103.539 117.729 1.00 55.23  ? 178 VAL B CG1 1 
ATOM   4150  C CG2 . VAL B 2 203 ? 124.470 103.919 115.286 1.00 50.00  ? 178 VAL B CG2 1 
ATOM   4151  N N   . GLU B 2 204 ? 127.412 101.695 117.962 1.00 64.07  ? 179 GLU B N   1 
ATOM   4152  C CA  . GLU B 2 204 ? 127.883 101.003 119.156 1.00 67.58  ? 179 GLU B CA  1 
ATOM   4153  C C   . GLU B 2 204 ? 129.138 101.640 119.738 1.00 67.34  ? 179 GLU B C   1 
ATOM   4154  O O   . GLU B 2 204 ? 129.412 101.467 120.931 1.00 67.85  ? 179 GLU B O   1 
ATOM   4155  C CB  . GLU B 2 204 ? 128.124 99.520  118.853 1.00 71.98  ? 179 GLU B CB  1 
ATOM   4156  C CG  . GLU B 2 204 ? 129.314 99.212  117.951 1.00 77.55  ? 179 GLU B CG  1 
ATOM   4157  C CD  . GLU B 2 204 ? 129.099 99.654  116.514 1.00 76.64  ? 179 GLU B CD  1 
ATOM   4158  O OE1 . GLU B 2 204 ? 127.927 99.774  116.098 1.00 70.81  ? 179 GLU B OE1 1 
ATOM   4159  O OE2 . GLU B 2 204 ? 130.099 99.865  115.796 1.00 78.24  ? 179 GLU B OE2 1 
ATOM   4160  N N   . ARG B 2 205 ? 129.900 102.374 118.931 1.00 64.31  ? 180 ARG B N   1 
ATOM   4161  C CA  . ARG B 2 205 ? 131.135 103.000 119.378 1.00 66.47  ? 180 ARG B CA  1 
ATOM   4162  C C   . ARG B 2 205 ? 130.931 104.432 119.851 1.00 63.39  ? 180 ARG B C   1 
ATOM   4163  O O   . ARG B 2 205 ? 131.903 105.084 120.245 1.00 58.88  ? 180 ARG B O   1 
ATOM   4164  C CB  . ARG B 2 205 ? 132.183 102.965 118.260 1.00 67.52  ? 180 ARG B CB  1 
ATOM   4165  C CG  . ARG B 2 205 ? 132.151 101.695 117.431 1.00 72.42  ? 180 ARG B CG  1 
ATOM   4166  C CD  . ARG B 2 205 ? 133.391 101.562 116.563 1.00 85.58  ? 180 ARG B CD  1 
ATOM   4167  N NE  . ARG B 2 205 ? 133.550 100.205 116.052 1.00 89.94  ? 180 ARG B NE  1 
ATOM   4168  C CZ  . ARG B 2 205 ? 133.102 99.788  114.876 1.00 88.62  ? 180 ARG B CZ  1 
ATOM   4169  N NH1 . ARG B 2 205 ? 132.448 100.597 114.059 1.00 81.60  ? 180 ARG B NH1 1 
ATOM   4170  N NH2 . ARG B 2 205 ? 133.310 98.525  114.514 1.00 88.43  ? 180 ARG B NH2 1 
ATOM   4171  N N   . ILE B 2 206 ? 129.700 104.932 119.824 1.00 67.22  ? 181 ILE B N   1 
ATOM   4172  C CA  . ILE B 2 206 ? 129.424 106.303 120.235 1.00 69.72  ? 181 ILE B CA  1 
ATOM   4173  C C   . ILE B 2 206 ? 129.442 106.375 121.753 1.00 74.58  ? 181 ILE B C   1 
ATOM   4174  O O   . ILE B 2 206 ? 128.783 105.581 122.435 1.00 74.93  ? 181 ILE B O   1 
ATOM   4175  C CB  . ILE B 2 206 ? 128.075 106.786 119.681 1.00 66.50  ? 181 ILE B CB  1 
ATOM   4176  C CG1 . ILE B 2 206 ? 128.110 106.894 118.160 1.00 64.86  ? 181 ILE B CG1 1 
ATOM   4177  C CG2 . ILE B 2 206 ? 127.707 108.132 120.279 1.00 54.12  ? 181 ILE B CG2 1 
ATOM   4178  C CD1 . ILE B 2 206 ? 126.743 107.106 117.559 1.00 63.68  ? 181 ILE B CD1 1 
ATOM   4179  N N   . GLU B 2 207 ? 130.195 107.329 122.286 1.00 74.45  ? 182 GLU B N   1 
ATOM   4180  C CA  . GLU B 2 207 ? 130.232 107.593 123.714 1.00 73.27  ? 182 GLU B CA  1 
ATOM   4181  C C   . GLU B 2 207 ? 129.798 109.031 123.940 1.00 67.36  ? 182 GLU B C   1 
ATOM   4182  O O   . GLU B 2 207 ? 130.353 109.955 123.337 1.00 67.92  ? 182 GLU B O   1 
ATOM   4183  C CB  . GLU B 2 207 ? 131.630 107.347 124.286 1.00 80.21  ? 182 GLU B CB  1 
ATOM   4184  C CG  . GLU B 2 207 ? 132.004 105.876 124.366 1.00 87.77  ? 182 GLU B CG  1 
ATOM   4185  C CD  . GLU B 2 207 ? 133.199 105.621 125.259 1.00 97.52  ? 182 GLU B CD  1 
ATOM   4186  O OE1 . GLU B 2 207 ? 133.943 106.582 125.547 1.00 96.16  ? 182 GLU B OE1 1 
ATOM   4187  O OE2 . GLU B 2 207 ? 133.398 104.458 125.668 1.00 101.08 ? 182 GLU B OE2 1 
ATOM   4188  N N   . LEU B 2 208 ? 128.808 109.212 124.807 1.00 59.99  ? 183 LEU B N   1 
ATOM   4189  C CA  . LEU B 2 208 ? 128.300 110.521 125.157 1.00 51.73  ? 183 LEU B CA  1 
ATOM   4190  C C   . LEU B 2 208 ? 128.499 110.760 126.646 1.00 50.65  ? 183 LEU B C   1 
ATOM   4191  O O   . LEU B 2 208 ? 128.176 109.881 127.458 1.00 47.35  ? 183 LEU B O   1 
ATOM   4192  C CB  . LEU B 2 208 ? 126.809 110.641 124.802 1.00 44.69  ? 183 LEU B CB  1 
ATOM   4193  C CG  . LEU B 2 208 ? 126.454 110.694 123.317 1.00 41.62  ? 183 LEU B CG  1 
ATOM   4194  C CD1 . LEU B 2 208 ? 124.981 110.411 123.107 1.00 39.92  ? 183 LEU B CD1 1 
ATOM   4195  C CD2 . LEU B 2 208 ? 126.810 112.051 122.756 1.00 40.70  ? 183 LEU B CD2 1 
ATOM   4196  N N   . PRO B 2 209 ? 129.040 111.911 127.043 1.00 48.20  ? 184 PRO B N   1 
ATOM   4197  C CA  . PRO B 2 209 ? 129.250 112.164 128.475 1.00 48.06  ? 184 PRO B CA  1 
ATOM   4198  C C   . PRO B 2 209 ? 127.965 112.180 129.276 1.00 51.97  ? 184 PRO B C   1 
ATOM   4199  O O   . PRO B 2 209 ? 128.006 111.946 130.490 1.00 52.67  ? 184 PRO B O   1 
ATOM   4200  C CB  . PRO B 2 209 ? 129.935 113.536 128.491 1.00 42.78  ? 184 PRO B CB  1 
ATOM   4201  C CG  . PRO B 2 209 ? 129.517 114.181 127.216 1.00 42.69  ? 184 PRO B CG  1 
ATOM   4202  C CD  . PRO B 2 209 ? 129.409 113.070 126.214 1.00 46.88  ? 184 PRO B CD  1 
ATOM   4203  N N   . GLN B 2 210 ? 126.824 112.444 128.639 1.00 49.18  ? 185 GLN B N   1 
ATOM   4204  C CA  . GLN B 2 210 ? 125.580 112.664 129.356 1.00 42.67  ? 185 GLN B CA  1 
ATOM   4205  C C   . GLN B 2 210 ? 124.503 111.634 129.049 1.00 39.17  ? 185 GLN B C   1 
ATOM   4206  O O   . GLN B 2 210 ? 123.626 111.417 129.892 1.00 46.19  ? 185 GLN B O   1 
ATOM   4207  C CB  . GLN B 2 210 ? 125.037 114.072 129.063 1.00 40.54  ? 185 GLN B CB  1 
ATOM   4208  C CG  . GLN B 2 210 ? 123.791 114.446 129.843 1.00 49.17  ? 185 GLN B CG  1 
ATOM   4209  C CD  . GLN B 2 210 ? 123.716 115.927 130.139 1.00 61.30  ? 185 GLN B CD  1 
ATOM   4210  O OE1 . GLN B 2 210 ? 123.176 116.340 131.165 1.00 60.54  ? 185 GLN B OE1 1 
ATOM   4211  N NE2 . GLN B 2 210 ? 124.260 116.738 129.239 1.00 65.90  ? 185 GLN B NE2 1 
ATOM   4212  N N   . PHE B 2 211 ? 124.561 110.971 127.903 1.00 36.17  ? 186 PHE B N   1 
ATOM   4213  C CA  . PHE B 2 211 ? 123.556 109.998 127.504 1.00 36.36  ? 186 PHE B CA  1 
ATOM   4214  C C   . PHE B 2 211 ? 124.216 108.651 127.234 1.00 41.60  ? 186 PHE B C   1 
ATOM   4215  O O   . PHE B 2 211 ? 125.433 108.487 127.353 1.00 50.55  ? 186 PHE B O   1 
ATOM   4216  C CB  . PHE B 2 211 ? 122.795 110.473 126.264 1.00 36.85  ? 186 PHE B CB  1 
ATOM   4217  C CG  . PHE B 2 211 ? 121.968 111.703 126.488 1.00 35.46  ? 186 PHE B CG  1 
ATOM   4218  C CD1 . PHE B 2 211 ? 122.501 112.960 126.271 1.00 35.47  ? 186 PHE B CD1 1 
ATOM   4219  C CD2 . PHE B 2 211 ? 120.655 111.602 126.906 1.00 36.53  ? 186 PHE B CD2 1 
ATOM   4220  C CE1 . PHE B 2 211 ? 121.740 114.093 126.472 1.00 37.32  ? 186 PHE B CE1 1 
ATOM   4221  C CE2 . PHE B 2 211 ? 119.891 112.731 127.108 1.00 36.72  ? 186 PHE B CE2 1 
ATOM   4222  C CZ  . PHE B 2 211 ? 120.434 113.977 126.890 1.00 36.37  ? 186 PHE B CZ  1 
ATOM   4223  N N   . SER B 2 212 ? 123.386 107.679 126.870 1.00 38.26  ? 187 SER B N   1 
ATOM   4224  C CA  . SER B 2 212 ? 123.842 106.391 126.370 1.00 40.74  ? 187 SER B CA  1 
ATOM   4225  C C   . SER B 2 212 ? 122.883 105.962 125.274 1.00 45.88  ? 187 SER B C   1 
ATOM   4226  O O   . SER B 2 212 ? 121.665 106.061 125.447 1.00 48.30  ? 187 SER B O   1 
ATOM   4227  C CB  . SER B 2 212 ? 123.896 105.342 127.485 1.00 45.65  ? 187 SER B CB  1 
ATOM   4228  O OG  . SER B 2 212 ? 122.600 105.060 127.980 1.00 52.77  ? 187 SER B OG  1 
ATOM   4229  N N   . ILE B 2 213 ? 123.423 105.484 124.155 1.00 47.36  ? 188 ILE B N   1 
ATOM   4230  C CA  . ILE B 2 213 ? 122.568 105.051 123.057 1.00 48.37  ? 188 ILE B CA  1 
ATOM   4231  C C   . ILE B 2 213 ? 121.909 103.732 123.434 1.00 51.17  ? 188 ILE B C   1 
ATOM   4232  O O   . ILE B 2 213 ? 122.585 102.712 123.612 1.00 54.88  ? 188 ILE B O   1 
ATOM   4233  C CB  . ILE B 2 213 ? 123.369 104.903 121.758 1.00 50.63  ? 188 ILE B CB  1 
ATOM   4234  C CG1 . ILE B 2 213 ? 124.291 106.101 121.531 1.00 46.46  ? 188 ILE B CG1 1 
ATOM   4235  C CG2 . ILE B 2 213 ? 122.422 104.754 120.583 1.00 53.66  ? 188 ILE B CG2 1 
ATOM   4236  C CD1 . ILE B 2 213 ? 123.599 107.426 121.546 1.00 42.70  ? 188 ILE B CD1 1 
ATOM   4237  N N   . VAL B 2 214 ? 120.586 103.744 123.555 1.00 50.71  ? 189 VAL B N   1 
ATOM   4238  C CA  . VAL B 2 214 ? 119.854 102.532 123.905 1.00 56.66  ? 189 VAL B CA  1 
ATOM   4239  C C   . VAL B 2 214 ? 119.461 101.750 122.660 1.00 60.15  ? 189 VAL B C   1 
ATOM   4240  O O   . VAL B 2 214 ? 119.559 100.521 122.631 1.00 63.82  ? 189 VAL B O   1 
ATOM   4241  C CB  . VAL B 2 214 ? 118.625 102.886 124.763 1.00 52.77  ? 189 VAL B CB  1 
ATOM   4242  C CG1 . VAL B 2 214 ? 117.738 101.669 124.950 1.00 53.48  ? 189 VAL B CG1 1 
ATOM   4243  C CG2 . VAL B 2 214 ? 119.070 103.423 126.107 1.00 51.16  ? 189 VAL B CG2 1 
ATOM   4244  N N   . GLU B 2 215 ? 119.036 102.455 121.617 1.00 57.85  ? 190 GLU B N   1 
ATOM   4245  C CA  . GLU B 2 215 ? 118.553 101.822 120.400 1.00 61.01  ? 190 GLU B CA  1 
ATOM   4246  C C   . GLU B 2 215 ? 118.655 102.834 119.270 1.00 55.51  ? 190 GLU B C   1 
ATOM   4247  O O   . GLU B 2 215 ? 118.792 104.038 119.501 1.00 54.63  ? 190 GLU B O   1 
ATOM   4248  C CB  . GLU B 2 215 ? 117.112 101.323 120.568 1.00 60.55  ? 190 GLU B CB  1 
ATOM   4249  C CG  . GLU B 2 215 ? 116.609 100.410 119.457 1.00 70.88  ? 190 GLU B CG  1 
ATOM   4250  C CD  . GLU B 2 215 ? 115.140 100.065 119.602 1.00 77.59  ? 190 GLU B CD  1 
ATOM   4251  O OE1 . GLU B 2 215 ? 114.454 100.713 120.418 1.00 76.43  ? 190 GLU B OE1 1 
ATOM   4252  O OE2 . GLU B 2 215 ? 114.672 99.147  118.897 1.00 80.10  ? 190 GLU B OE2 1 
ATOM   4253  N N   . HIS B 2 216 ? 118.594 102.329 118.042 1.00 51.84  ? 191 HIS B N   1 
ATOM   4254  C CA  . HIS B 2 216 ? 118.419 103.179 116.877 1.00 48.13  ? 191 HIS B CA  1 
ATOM   4255  C C   . HIS B 2 216 ? 117.570 102.429 115.864 1.00 50.25  ? 191 HIS B C   1 
ATOM   4256  O O   . HIS B 2 216 ? 117.615 101.199 115.786 1.00 54.56  ? 191 HIS B O   1 
ATOM   4257  C CB  . HIS B 2 216 ? 119.763 103.603 116.268 1.00 46.97  ? 191 HIS B CB  1 
ATOM   4258  C CG  . HIS B 2 216 ? 120.463 102.516 115.515 1.00 55.74  ? 191 HIS B CG  1 
ATOM   4259  N ND1 . HIS B 2 216 ? 121.393 101.684 116.102 1.00 59.33  ? 191 HIS B ND1 1 
ATOM   4260  C CD2 . HIS B 2 216 ? 120.381 102.133 114.219 1.00 53.24  ? 191 HIS B CD2 1 
ATOM   4261  C CE1 . HIS B 2 216 ? 121.847 100.831 115.202 1.00 54.93  ? 191 HIS B CE1 1 
ATOM   4262  N NE2 . HIS B 2 216 ? 121.248 101.081 114.051 1.00 54.13  ? 191 HIS B NE2 1 
ATOM   4263  N N   . ARG B 2 217 ? 116.791 103.183 115.095 1.00 47.51  ? 192 ARG B N   1 
ATOM   4264  C CA  . ARG B 2 217 ? 115.869 102.618 114.125 1.00 49.54  ? 192 ARG B CA  1 
ATOM   4265  C C   . ARG B 2 217 ? 116.003 103.347 112.800 1.00 52.95  ? 192 ARG B C   1 
ATOM   4266  O O   . ARG B 2 217 ? 116.322 104.537 112.756 1.00 53.25  ? 192 ARG B O   1 
ATOM   4267  C CB  . ARG B 2 217 ? 114.414 102.702 114.602 1.00 52.39  ? 192 ARG B CB  1 
ATOM   4268  C CG  . ARG B 2 217 ? 114.130 101.942 115.882 1.00 65.93  ? 192 ARG B CG  1 
ATOM   4269  C CD  . ARG B 2 217 ? 112.670 102.074 116.280 1.00 66.67  ? 192 ARG B CD  1 
ATOM   4270  N NE  . ARG B 2 217 ? 112.404 101.474 117.582 1.00 64.17  ? 192 ARG B NE  1 
ATOM   4271  C CZ  . ARG B 2 217 ? 111.286 101.653 118.272 1.00 65.57  ? 192 ARG B CZ  1 
ATOM   4272  N NH1 . ARG B 2 217 ? 110.306 102.414 117.814 1.00 64.61  ? 192 ARG B NH1 1 
ATOM   4273  N NH2 . ARG B 2 217 ? 111.151 101.058 119.454 1.00 70.69  ? 192 ARG B NH2 1 
ATOM   4274  N N   . LEU B 2 218 ? 115.758 102.616 111.720 1.00 53.83  ? 193 LEU B N   1 
ATOM   4275  C CA  . LEU B 2 218 ? 115.729 103.174 110.377 1.00 46.93  ? 193 LEU B CA  1 
ATOM   4276  C C   . LEU B 2 218 ? 114.310 103.063 109.844 1.00 47.68  ? 193 LEU B C   1 
ATOM   4277  O O   . LEU B 2 218 ? 113.714 101.981 109.877 1.00 53.95  ? 193 LEU B O   1 
ATOM   4278  C CB  . LEU B 2 218 ? 116.707 102.445 109.456 1.00 43.31  ? 193 LEU B CB  1 
ATOM   4279  C CG  . LEU B 2 218 ? 118.112 102.296 110.034 1.00 38.71  ? 193 LEU B CG  1 
ATOM   4280  C CD1 . LEU B 2 218 ? 119.032 101.583 109.060 1.00 44.19  ? 193 LEU B CD1 1 
ATOM   4281  C CD2 . LEU B 2 218 ? 118.660 103.654 110.405 1.00 34.95  ? 193 LEU B CD2 1 
ATOM   4282  N N   . VAL B 2 219 ? 113.774 104.176 109.357 1.00 43.44  ? 194 VAL B N   1 
ATOM   4283  C CA  . VAL B 2 219 ? 112.414 104.225 108.839 1.00 41.28  ? 194 VAL B CA  1 
ATOM   4284  C C   . VAL B 2 219 ? 112.450 104.773 107.421 1.00 40.39  ? 194 VAL B C   1 
ATOM   4285  O O   . VAL B 2 219 ? 113.117 105.777 107.154 1.00 43.33  ? 194 VAL B O   1 
ATOM   4286  C CB  . VAL B 2 219 ? 111.505 105.094 109.730 1.00 43.05  ? 194 VAL B CB  1 
ATOM   4287  C CG1 . VAL B 2 219 ? 110.153 105.313 109.072 1.00 49.69  ? 194 VAL B CG1 1 
ATOM   4288  C CG2 . VAL B 2 219 ? 111.344 104.459 111.099 1.00 50.65  ? 194 VAL B CG2 1 
ATOM   4289  N N   . SER B 2 220 ? 111.736 104.110 106.518 1.00 41.61  ? 195 SER B N   1 
ATOM   4290  C CA  . SER B 2 220 ? 111.534 104.583 105.157 1.00 45.24  ? 195 SER B CA  1 
ATOM   4291  C C   . SER B 2 220 ? 110.045 104.820 104.960 1.00 50.82  ? 195 SER B C   1 
ATOM   4292  O O   . SER B 2 220 ? 109.228 103.954 105.290 1.00 55.40  ? 195 SER B O   1 
ATOM   4293  C CB  . SER B 2 220 ? 112.060 103.578 104.131 1.00 45.64  ? 195 SER B CB  1 
ATOM   4294  O OG  . SER B 2 220 ? 111.915 104.078 102.814 1.00 46.38  ? 195 SER B OG  1 
ATOM   4295  N N   . ARG B 2 221 ? 109.694 105.985 104.427 1.00 51.11  ? 196 ARG B N   1 
ATOM   4296  C CA  . ARG B 2 221 ? 108.294 106.357 104.296 1.00 52.84  ? 196 ARG B CA  1 
ATOM   4297  C C   . ARG B 2 221 ? 108.167 107.430 103.227 1.00 57.93  ? 196 ARG B C   1 
ATOM   4298  O O   . ARG B 2 221 ? 109.152 108.041 102.808 1.00 60.98  ? 196 ARG B O   1 
ATOM   4299  C CB  . ARG B 2 221 ? 107.719 106.857 105.623 1.00 50.18  ? 196 ARG B CB  1 
ATOM   4300  C CG  . ARG B 2 221 ? 108.625 107.823 106.359 1.00 51.26  ? 196 ARG B CG  1 
ATOM   4301  C CD  . ARG B 2 221 ? 107.928 108.409 107.569 1.00 61.99  ? 196 ARG B CD  1 
ATOM   4302  N NE  . ARG B 2 221 ? 106.757 109.186 107.180 1.00 72.96  ? 196 ARG B NE  1 
ATOM   4303  C CZ  . ARG B 2 221 ? 106.302 110.241 107.840 1.00 77.93  ? 196 ARG B CZ  1 
ATOM   4304  N NH1 . ARG B 2 221 ? 106.924 110.709 108.909 1.00 74.14  ? 196 ARG B NH1 1 
ATOM   4305  N NH2 . ARG B 2 221 ? 105.202 110.851 107.408 1.00 79.83  ? 196 ARG B NH2 1 
ATOM   4306  N N   . ASN B 2 222 ? 106.932 107.639 102.786 1.00 62.32  ? 197 ASN B N   1 
ATOM   4307  C CA  . ASN B 2 222 ? 106.603 108.623 101.760 1.00 69.99  ? 197 ASN B CA  1 
ATOM   4308  C C   . ASN B 2 222 ? 105.642 109.622 102.394 1.00 75.58  ? 197 ASN B C   1 
ATOM   4309  O O   . ASN B 2 222 ? 104.436 109.367 102.472 1.00 76.82  ? 197 ASN B O   1 
ATOM   4310  C CB  . ASN B 2 222 ? 105.996 107.953 100.533 1.00 70.35  ? 197 ASN B CB  1 
ATOM   4311  C CG  . ASN B 2 222 ? 106.962 107.010 99.849  1.00 67.29  ? 197 ASN B CG  1 
ATOM   4312  O OD1 . ASN B 2 222 ? 108.178 107.171 99.947  1.00 64.04  ? 197 ASN B OD1 1 
ATOM   4313  N ND2 . ASN B 2 222 ? 106.426 106.015 99.153  1.00 68.22  ? 197 ASN B ND2 1 
ATOM   4314  N N   . VAL B 2 223 ? 106.179 110.750 102.863 1.00 77.80  ? 198 VAL B N   1 
ATOM   4315  C CA  . VAL B 2 223 ? 105.330 111.800 103.404 1.00 80.10  ? 198 VAL B CA  1 
ATOM   4316  C C   . VAL B 2 223 ? 104.384 112.290 102.311 1.00 84.94  ? 198 VAL B C   1 
ATOM   4317  O O   . VAL B 2 223 ? 104.741 112.355 101.128 1.00 84.71  ? 198 VAL B O   1 
ATOM   4318  C CB  . VAL B 2 223 ? 106.185 112.944 103.973 1.00 73.89  ? 198 VAL B CB  1 
ATOM   4319  C CG1 . VAL B 2 223 ? 105.310 114.049 104.530 1.00 80.99  ? 198 VAL B CG1 1 
ATOM   4320  C CG2 . VAL B 2 223 ? 107.118 112.414 105.049 1.00 63.88  ? 198 VAL B CG2 1 
ATOM   4321  N N   . VAL B 2 224 ? 103.164 112.642 102.712 1.00 90.60  ? 199 VAL B N   1 
ATOM   4322  C CA  . VAL B 2 224 ? 102.113 113.061 101.794 1.00 93.86  ? 199 VAL B CA  1 
ATOM   4323  C C   . VAL B 2 224 ? 101.691 114.484 102.130 1.00 97.99  ? 199 VAL B C   1 
ATOM   4324  O O   . VAL B 2 224 ? 101.402 114.795 103.291 1.00 95.65  ? 199 VAL B O   1 
ATOM   4325  C CB  . VAL B 2 224 ? 100.904 112.109 101.850 1.00 86.06  ? 199 VAL B CB  1 
ATOM   4326  C CG1 . VAL B 2 224 ? 99.800  112.594 100.923 1.00 85.73  ? 199 VAL B CG1 1 
ATOM   4327  C CG2 . VAL B 2 224 ? 101.327 110.691 101.497 1.00 74.71  ? 199 VAL B CG2 1 
ATOM   4328  N N   . PHE B 2 225 ? 101.663 115.347 101.113 1.00 100.21 ? 200 PHE B N   1 
ATOM   4329  C CA  . PHE B 2 225 ? 101.112 116.688 101.259 1.00 105.38 ? 200 PHE B CA  1 
ATOM   4330  C C   . PHE B 2 225 ? 100.067 116.928 100.179 1.00 111.46 ? 200 PHE B C   1 
ATOM   4331  O O   . PHE B 2 225 ? 99.687  115.998 99.460  1.00 109.72 ? 200 PHE B O   1 
ATOM   4332  C CB  . PHE B 2 225 ? 102.200 117.761 101.156 1.00 105.47 ? 200 PHE B CB  1 
ATOM   4333  C CG  . PHE B 2 225 ? 103.286 117.644 102.185 1.00 105.22 ? 200 PHE B CG  1 
ATOM   4334  C CD1 . PHE B 2 225 ? 103.029 117.919 103.517 1.00 107.13 ? 200 PHE B CD1 1 
ATOM   4335  C CD2 . PHE B 2 225 ? 104.575 117.300 101.813 1.00 101.59 ? 200 PHE B CD2 1 
ATOM   4336  C CE1 . PHE B 2 225 ? 104.030 117.827 104.462 1.00 107.91 ? 200 PHE B CE1 1 
ATOM   4337  C CE2 . PHE B 2 225 ? 105.581 117.208 102.754 1.00 96.56  ? 200 PHE B CE2 1 
ATOM   4338  C CZ  . PHE B 2 225 ? 105.308 117.474 104.079 1.00 102.35 ? 200 PHE B CZ  1 
ATOM   4339  N N   . ALA B 2 226 ? 99.589  118.169 100.061 1.00 118.15 ? 201 ALA B N   1 
ATOM   4340  C CA  . ALA B 2 226 ? 98.674  118.500 98.975  1.00 118.44 ? 201 ALA B CA  1 
ATOM   4341  C C   . ALA B 2 226 ? 99.351  118.334 97.620  1.00 126.22 ? 201 ALA B C   1 
ATOM   4342  O O   . ALA B 2 226 ? 98.739  117.836 96.667  1.00 123.61 ? 201 ALA B O   1 
ATOM   4343  C CB  . ALA B 2 226 ? 98.148  119.925 99.145  1.00 111.59 ? 201 ALA B CB  1 
ATOM   4344  N N   . THR B 2 227 ? 100.614 118.757 97.516  1.00 125.77 ? 202 THR B N   1 
ATOM   4345  C CA  . THR B 2 227 ? 101.334 118.654 96.251  1.00 118.75 ? 202 THR B CA  1 
ATOM   4346  C C   . THR B 2 227 ? 101.505 117.201 95.825  1.00 116.04 ? 202 THR B C   1 
ATOM   4347  O O   . THR B 2 227 ? 101.330 116.867 94.647  1.00 114.60 ? 202 THR B O   1 
ATOM   4348  C CB  . THR B 2 227 ? 102.691 119.350 96.362  1.00 114.29 ? 202 THR B CB  1 
ATOM   4349  O OG1 . THR B 2 227 ? 103.365 118.903 97.544  1.00 109.39 ? 202 THR B OG1 1 
ATOM   4350  C CG2 . THR B 2 227 ? 102.513 120.860 96.427  1.00 113.66 ? 202 THR B CG2 1 
ATOM   4351  N N   . GLY B 2 228 ? 101.842 116.326 96.761  1.00 112.06 ? 203 GLY B N   1 
ATOM   4352  C CA  . GLY B 2 228 ? 101.995 114.921 96.450  1.00 107.73 ? 203 GLY B CA  1 
ATOM   4353  C C   . GLY B 2 228 ? 102.891 114.231 97.462  1.00 100.49 ? 203 GLY B C   1 
ATOM   4354  O O   . GLY B 2 228 ? 103.209 114.775 98.518  1.00 93.71  ? 203 GLY B O   1 
ATOM   4355  N N   . ALA B 2 229 ? 103.274 113.006 97.109  1.00 98.73  ? 204 ALA B N   1 
ATOM   4356  C CA  . ALA B 2 229 ? 104.141 112.192 97.950  1.00 89.20  ? 204 ALA B CA  1 
ATOM   4357  C C   . ALA B 2 229 ? 105.608 112.557 97.755  1.00 87.79  ? 204 ALA B C   1 
ATOM   4358  O O   . ALA B 2 229 ? 106.076 112.729 96.626  1.00 87.82  ? 204 ALA B O   1 
ATOM   4359  C CB  . ALA B 2 229 ? 103.933 110.708 97.648  1.00 73.59  ? 204 ALA B CB  1 
ATOM   4360  N N   . TYR B 2 230 ? 106.334 112.669 98.868  1.00 83.22  ? 205 TYR B N   1 
ATOM   4361  C CA  . TYR B 2 230 ? 107.748 113.006 98.883  1.00 76.26  ? 205 TYR B CA  1 
ATOM   4362  C C   . TYR B 2 230 ? 108.534 111.916 99.601  1.00 71.48  ? 205 TYR B C   1 
ATOM   4363  O O   . TYR B 2 230 ? 108.078 111.404 100.628 1.00 67.03  ? 205 TYR B O   1 
ATOM   4364  C CB  . TYR B 2 230 ? 108.009 114.351 99.578  1.00 75.90  ? 205 TYR B CB  1 
ATOM   4365  C CG  . TYR B 2 230 ? 107.461 115.553 98.849  1.00 81.12  ? 205 TYR B CG  1 
ATOM   4366  C CD1 . TYR B 2 230 ? 106.104 115.832 98.851  1.00 88.95  ? 205 TYR B CD1 1 
ATOM   4367  C CD2 . TYR B 2 230 ? 108.306 116.416 98.163  1.00 79.29  ? 205 TYR B CD2 1 
ATOM   4368  C CE1 . TYR B 2 230 ? 105.601 116.930 98.190  1.00 96.17  ? 205 TYR B CE1 1 
ATOM   4369  C CE2 . TYR B 2 230 ? 107.812 117.520 97.498  1.00 84.44  ? 205 TYR B CE2 1 
ATOM   4370  C CZ  . TYR B 2 230 ? 106.457 117.772 97.514  1.00 96.81  ? 205 TYR B CZ  1 
ATOM   4371  O OH  . TYR B 2 230 ? 105.955 118.870 96.854  1.00 102.67 ? 205 TYR B OH  1 
ATOM   4372  N N   . PRO B 2 231 ? 109.706 111.539 99.093  1.00 68.07  ? 206 PRO B N   1 
ATOM   4373  C CA  . PRO B 2 231 ? 110.504 110.522 99.783  1.00 57.12  ? 206 PRO B CA  1 
ATOM   4374  C C   . PRO B 2 231 ? 111.008 111.027 101.123 1.00 47.78  ? 206 PRO B C   1 
ATOM   4375  O O   . PRO B 2 231 ? 111.296 112.212 101.302 1.00 46.30  ? 206 PRO B O   1 
ATOM   4376  C CB  . PRO B 2 231 ? 111.665 110.265 98.817  1.00 54.42  ? 206 PRO B CB  1 
ATOM   4377  C CG  . PRO B 2 231 ? 111.775 111.519 98.023  1.00 60.94  ? 206 PRO B CG  1 
ATOM   4378  C CD  . PRO B 2 231 ? 110.380 112.055 97.890  1.00 71.41  ? 206 PRO B CD  1 
ATOM   4379  N N   . ARG B 2 232 ? 111.110 110.104 102.075 1.00 43.53  ? 207 ARG B N   1 
ATOM   4380  C CA  . ARG B 2 232 ? 111.556 110.437 103.418 1.00 38.62  ? 207 ARG B CA  1 
ATOM   4381  C C   . ARG B 2 232 ? 112.326 109.273 104.017 1.00 39.79  ? 207 ARG B C   1 
ATOM   4382  O O   . ARG B 2 232 ? 111.902 108.120 103.909 1.00 44.36  ? 207 ARG B O   1 
ATOM   4383  C CB  . ARG B 2 232 ? 110.378 110.793 104.329 1.00 42.10  ? 207 ARG B CB  1 
ATOM   4384  C CG  . ARG B 2 232 ? 110.767 110.961 105.786 1.00 39.79  ? 207 ARG B CG  1 
ATOM   4385  C CD  . ARG B 2 232 ? 111.497 112.266 106.019 1.00 40.57  ? 207 ARG B CD  1 
ATOM   4386  N NE  . ARG B 2 232 ? 110.612 113.413 105.866 1.00 50.81  ? 207 ARG B NE  1 
ATOM   4387  C CZ  . ARG B 2 232 ? 109.956 113.986 106.865 1.00 45.67  ? 207 ARG B CZ  1 
ATOM   4388  N NH1 . ARG B 2 232 ? 110.067 113.546 108.107 1.00 40.73  ? 207 ARG B NH1 1 
ATOM   4389  N NH2 . ARG B 2 232 ? 109.168 115.027 106.611 1.00 43.29  ? 207 ARG B NH2 1 
ATOM   4390  N N   . LEU B 2 233 ? 113.458 109.583 104.639 1.00 39.35  ? 208 LEU B N   1 
ATOM   4391  C CA  . LEU B 2 233 ? 114.195 108.624 105.448 1.00 36.50  ? 208 LEU B CA  1 
ATOM   4392  C C   . LEU B 2 233 ? 114.424 109.243 106.813 1.00 34.13  ? 208 LEU B C   1 
ATOM   4393  O O   . LEU B 2 233 ? 114.758 110.426 106.919 1.00 38.25  ? 208 LEU B O   1 
ATOM   4394  C CB  . LEU B 2 233 ? 115.543 108.235 104.831 1.00 31.92  ? 208 LEU B CB  1 
ATOM   4395  C CG  . LEU B 2 233 ? 115.547 107.518 103.486 1.00 34.92  ? 208 LEU B CG  1 
ATOM   4396  C CD1 . LEU B 2 233 ? 116.973 107.262 103.044 1.00 42.19  ? 208 LEU B CD1 1 
ATOM   4397  C CD2 . LEU B 2 233 ? 114.774 106.219 103.571 1.00 39.95  ? 208 LEU B CD2 1 
ATOM   4398  N N   . SER B 2 234 ? 114.238 108.446 107.855 1.00 31.10  ? 209 SER B N   1 
ATOM   4399  C CA  . SER B 2 234 ? 114.389 108.927 109.217 1.00 32.00  ? 209 SER B CA  1 
ATOM   4400  C C   . SER B 2 234 ? 115.360 108.020 109.949 1.00 33.84  ? 209 SER B C   1 
ATOM   4401  O O   . SER B 2 234 ? 115.199 106.796 109.946 1.00 43.29  ? 209 SER B O   1 
ATOM   4402  C CB  . SER B 2 234 ? 113.044 108.969 109.946 1.00 39.49  ? 209 SER B CB  1 
ATOM   4403  O OG  . SER B 2 234 ? 112.124 109.806 109.266 1.00 49.23  ? 209 SER B OG  1 
ATOM   4404  N N   . LEU B 2 235 ? 116.356 108.623 110.579 1.00 31.83  ? 210 LEU B N   1 
ATOM   4405  C CA  . LEU B 2 235 ? 117.262 107.925 111.475 1.00 31.96  ? 210 LEU B CA  1 
ATOM   4406  C C   . LEU B 2 235 ? 117.028 108.496 112.861 1.00 35.41  ? 210 LEU B C   1 
ATOM   4407  O O   . LEU B 2 235 ? 117.143 109.708 113.061 1.00 39.24  ? 210 LEU B O   1 
ATOM   4408  C CB  . LEU B 2 235 ? 118.715 108.104 111.035 1.00 34.04  ? 210 LEU B CB  1 
ATOM   4409  C CG  . LEU B 2 235 ? 119.817 107.812 112.052 1.00 33.65  ? 210 LEU B CG  1 
ATOM   4410  C CD1 . LEU B 2 235 ? 119.746 106.375 112.530 1.00 40.15  ? 210 LEU B CD1 1 
ATOM   4411  C CD2 . LEU B 2 235 ? 121.178 108.110 111.449 1.00 28.91  ? 210 LEU B CD2 1 
ATOM   4412  N N   . SER B 2 236 ? 116.708 107.629 113.811 1.00 35.03  ? 211 SER B N   1 
ATOM   4413  C CA  . SER B 2 236 ? 116.338 108.060 115.147 1.00 35.13  ? 211 SER B CA  1 
ATOM   4414  C C   . SER B 2 236 ? 117.113 107.260 116.176 1.00 37.56  ? 211 SER B C   1 
ATOM   4415  O O   . SER B 2 236 ? 117.353 106.063 115.997 1.00 46.69  ? 211 SER B O   1 
ATOM   4416  C CB  . SER B 2 236 ? 114.833 107.899 115.389 1.00 39.32  ? 211 SER B CB  1 
ATOM   4417  O OG  . SER B 2 236 ? 114.420 106.564 115.164 1.00 43.80  ? 211 SER B OG  1 
ATOM   4418  N N   . PHE B 2 237 ? 117.500 107.933 117.250 1.00 34.96  ? 212 PHE B N   1 
ATOM   4419  C CA  . PHE B 2 237 ? 118.186 107.312 118.367 1.00 37.73  ? 212 PHE B CA  1 
ATOM   4420  C C   . PHE B 2 237 ? 117.360 107.531 119.623 1.00 36.62  ? 212 PHE B C   1 
ATOM   4421  O O   . PHE B 2 237 ? 116.708 108.566 119.779 1.00 42.38  ? 212 PHE B O   1 
ATOM   4422  C CB  . PHE B 2 237 ? 119.590 107.897 118.571 1.00 40.43  ? 212 PHE B CB  1 
ATOM   4423  C CG  . PHE B 2 237 ? 120.348 108.136 117.295 1.00 42.68  ? 212 PHE B CG  1 
ATOM   4424  C CD1 . PHE B 2 237 ? 120.202 109.324 116.598 1.00 37.24  ? 212 PHE B CD1 1 
ATOM   4425  C CD2 . PHE B 2 237 ? 121.210 107.176 116.794 1.00 46.37  ? 212 PHE B CD2 1 
ATOM   4426  C CE1 . PHE B 2 237 ? 120.897 109.548 115.429 1.00 35.96  ? 212 PHE B CE1 1 
ATOM   4427  C CE2 . PHE B 2 237 ? 121.906 107.397 115.624 1.00 44.03  ? 212 PHE B CE2 1 
ATOM   4428  C CZ  . PHE B 2 237 ? 121.748 108.584 114.943 1.00 37.13  ? 212 PHE B CZ  1 
ATOM   4429  N N   . ARG B 2 238 ? 117.390 106.556 120.521 1.00 38.55  ? 213 ARG B N   1 
ATOM   4430  C CA  . ARG B 2 238 ? 116.751 106.694 121.820 1.00 42.59  ? 213 ARG B CA  1 
ATOM   4431  C C   . ARG B 2 238 ? 117.861 106.876 122.841 1.00 42.99  ? 213 ARG B C   1 
ATOM   4432  O O   . ARG B 2 238 ? 118.709 105.994 123.008 1.00 49.80  ? 213 ARG B O   1 
ATOM   4433  C CB  . ARG B 2 238 ? 115.872 105.490 122.161 1.00 48.51  ? 213 ARG B CB  1 
ATOM   4434  C CG  . ARG B 2 238 ? 114.443 105.895 122.493 1.00 48.26  ? 213 ARG B CG  1 
ATOM   4435  C CD  . ARG B 2 238 ? 113.475 104.723 122.538 1.00 58.24  ? 213 ARG B CD  1 
ATOM   4436  N NE  . ARG B 2 238 ? 113.756 103.812 123.641 1.00 66.48  ? 213 ARG B NE  1 
ATOM   4437  C CZ  . ARG B 2 238 ? 114.192 102.569 123.497 1.00 70.30  ? 213 ARG B CZ  1 
ATOM   4438  N NH1 . ARG B 2 238 ? 114.394 102.041 122.302 1.00 75.86  ? 213 ARG B NH1 1 
ATOM   4439  N NH2 . ARG B 2 238 ? 114.418 101.832 124.581 1.00 65.68  ? 213 ARG B NH2 1 
ATOM   4440  N N   . LEU B 2 239 ? 117.853 108.021 123.511 1.00 36.18  ? 214 LEU B N   1 
ATOM   4441  C CA  . LEU B 2 239 ? 118.890 108.392 124.459 1.00 34.87  ? 214 LEU B CA  1 
ATOM   4442  C C   . LEU B 2 239 ? 118.338 108.285 125.870 1.00 41.12  ? 214 LEU B C   1 
ATOM   4443  O O   . LEU B 2 239 ? 117.279 108.845 126.170 1.00 48.64  ? 214 LEU B O   1 
ATOM   4444  C CB  . LEU B 2 239 ? 119.370 109.821 124.199 1.00 32.21  ? 214 LEU B CB  1 
ATOM   4445  C CG  . LEU B 2 239 ? 119.675 110.209 122.753 1.00 33.38  ? 214 LEU B CG  1 
ATOM   4446  C CD1 . LEU B 2 239 ? 120.025 111.686 122.652 1.00 34.56  ? 214 LEU B CD1 1 
ATOM   4447  C CD2 . LEU B 2 239 ? 120.779 109.359 122.187 1.00 38.64  ? 214 LEU B CD2 1 
ATOM   4448  N N   . LYS B 2 240 ? 119.056 107.577 126.734 1.00 39.21  ? 215 LYS B N   1 
ATOM   4449  C CA  . LYS B 2 240 ? 118.674 107.435 128.131 1.00 39.71  ? 215 LYS B CA  1 
ATOM   4450  C C   . LYS B 2 240 ? 119.747 108.112 128.964 1.00 38.66  ? 215 LYS B C   1 
ATOM   4451  O O   . LYS B 2 240 ? 120.900 107.668 128.976 1.00 42.56  ? 215 LYS B O   1 
ATOM   4452  C CB  . LYS B 2 240 ? 118.521 105.965 128.523 1.00 44.33  ? 215 LYS B CB  1 
ATOM   4453  C CG  . LYS B 2 240 ? 117.855 105.744 129.869 1.00 46.98  ? 215 LYS B CG  1 
ATOM   4454  C CD  . LYS B 2 240 ? 117.673 104.263 130.152 1.00 56.54  ? 215 LYS B CD  1 
ATOM   4455  C CE  . LYS B 2 240 ? 116.886 104.039 131.431 1.00 70.35  ? 215 LYS B CE  1 
ATOM   4456  N NZ  . LYS B 2 240 ? 116.692 102.589 131.707 1.00 76.30  ? 215 LYS B NZ  1 
ATOM   4457  N N   . ARG B 2 241 ? 119.368 109.186 129.648 1.00 34.65  ? 216 ARG B N   1 
ATOM   4458  C CA  . ARG B 2 241 ? 120.340 109.991 130.370 1.00 35.60  ? 216 ARG B CA  1 
ATOM   4459  C C   . ARG B 2 241 ? 120.963 109.191 131.503 1.00 40.94  ? 216 ARG B C   1 
ATOM   4460  O O   . ARG B 2 241 ? 120.295 108.390 132.161 1.00 47.46  ? 216 ARG B O   1 
ATOM   4461  C CB  . ARG B 2 241 ? 119.674 111.257 130.907 1.00 31.08  ? 216 ARG B CB  1 
ATOM   4462  C CG  . ARG B 2 241 ? 120.647 112.311 131.391 1.00 31.17  ? 216 ARG B CG  1 
ATOM   4463  C CD  . ARG B 2 241 ? 119.913 113.544 131.872 1.00 32.73  ? 216 ARG B CD  1 
ATOM   4464  N NE  . ARG B 2 241 ? 119.008 114.053 130.849 1.00 32.51  ? 216 ARG B NE  1 
ATOM   4465  C CZ  . ARG B 2 241 ? 119.335 114.970 129.950 1.00 37.26  ? 216 ARG B CZ  1 
ATOM   4466  N NH1 . ARG B 2 241 ? 120.536 115.523 129.932 1.00 38.43  ? 216 ARG B NH1 1 
ATOM   4467  N NH2 . ARG B 2 241 ? 118.432 115.346 129.049 1.00 37.65  ? 216 ARG B NH2 1 
ATOM   4468  N N   . ASN B 2 242 ? 122.254 109.411 131.728 1.00 38.18  ? 217 ASN B N   1 
ATOM   4469  C CA  . ASN B 2 242 ? 122.932 108.785 132.850 1.00 40.85  ? 217 ASN B CA  1 
ATOM   4470  C C   . ASN B 2 242 ? 122.568 109.509 134.135 1.00 47.96  ? 217 ASN B C   1 
ATOM   4471  O O   . ASN B 2 242 ? 122.389 110.729 134.152 1.00 48.54  ? 217 ASN B O   1 
ATOM   4472  C CB  . ASN B 2 242 ? 124.446 108.798 132.650 1.00 36.74  ? 217 ASN B CB  1 
ATOM   4473  C CG  . ASN B 2 242 ? 124.866 108.147 131.355 1.00 39.18  ? 217 ASN B CG  1 
ATOM   4474  O OD1 . ASN B 2 242 ? 124.244 107.189 130.899 1.00 41.40  ? 217 ASN B OD1 1 
ATOM   4475  N ND2 . ASN B 2 242 ? 125.929 108.663 130.752 1.00 40.51  ? 217 ASN B ND2 1 
ATOM   4476  N N   . ILE B 2 243 ? 122.462 108.746 135.218 1.00 50.66  ? 218 ILE B N   1 
ATOM   4477  C CA  . ILE B 2 243 ? 121.940 109.264 136.475 1.00 45.30  ? 218 ILE B CA  1 
ATOM   4478  C C   . ILE B 2 243 ? 123.017 109.426 137.534 1.00 42.19  ? 218 ILE B C   1 
ATOM   4479  O O   . ILE B 2 243 ? 122.746 110.043 138.578 1.00 43.90  ? 218 ILE B O   1 
ATOM   4480  C CB  . ILE B 2 243 ? 120.792 108.379 137.009 1.00 37.74  ? 218 ILE B CB  1 
ATOM   4481  C CG1 . ILE B 2 243 ? 119.916 109.158 137.993 1.00 36.48  ? 218 ILE B CG1 1 
ATOM   4482  C CG2 . ILE B 2 243 ? 121.347 107.121 137.654 1.00 38.45  ? 218 ILE B CG2 1 
ATOM   4483  C CD1 . ILE B 2 243 ? 119.107 110.253 137.345 1.00 37.88  ? 218 ILE B CD1 1 
ATOM   4484  N N   . GLY B 2 244 ? 124.232 108.923 137.300 1.00 33.91  ? 219 GLY B N   1 
ATOM   4485  C CA  . GLY B 2 244 ? 125.225 108.909 138.361 1.00 33.60  ? 219 GLY B CA  1 
ATOM   4486  C C   . GLY B 2 244 ? 125.559 110.301 138.859 1.00 40.05  ? 219 GLY B C   1 
ATOM   4487  O O   . GLY B 2 244 ? 125.704 110.521 140.063 1.00 45.49  ? 219 GLY B O   1 
ATOM   4488  N N   . TYR B 2 245 ? 125.697 111.260 137.939 1.00 39.46  ? 220 TYR B N   1 
ATOM   4489  C CA  . TYR B 2 245 ? 126.042 112.616 138.349 1.00 39.28  ? 220 TYR B CA  1 
ATOM   4490  C C   . TYR B 2 245 ? 124.925 113.229 139.181 1.00 41.92  ? 220 TYR B C   1 
ATOM   4491  O O   . TYR B 2 245 ? 125.185 113.890 140.192 1.00 40.62  ? 220 TYR B O   1 
ATOM   4492  C CB  . TYR B 2 245 ? 126.337 113.486 137.128 1.00 37.31  ? 220 TYR B CB  1 
ATOM   4493  C CG  . TYR B 2 245 ? 126.205 114.970 137.388 1.00 43.66  ? 220 TYR B CG  1 
ATOM   4494  C CD1 . TYR B 2 245 ? 127.029 115.612 138.303 1.00 49.87  ? 220 TYR B CD1 1 
ATOM   4495  C CD2 . TYR B 2 245 ? 125.250 115.728 136.724 1.00 45.10  ? 220 TYR B CD2 1 
ATOM   4496  C CE1 . TYR B 2 245 ? 126.908 116.967 138.544 1.00 50.37  ? 220 TYR B CE1 1 
ATOM   4497  C CE2 . TYR B 2 245 ? 125.122 117.083 136.961 1.00 49.17  ? 220 TYR B CE2 1 
ATOM   4498  C CZ  . TYR B 2 245 ? 125.952 117.697 137.874 1.00 54.10  ? 220 TYR B CZ  1 
ATOM   4499  O OH  . TYR B 2 245 ? 125.830 119.046 138.112 1.00 53.28  ? 220 TYR B OH  1 
ATOM   4500  N N   . PHE B 2 246 ? 123.670 113.006 138.780 1.00 40.95  ? 221 PHE B N   1 
ATOM   4501  C CA  . PHE B 2 246 ? 122.561 113.649 139.472 1.00 37.42  ? 221 PHE B CA  1 
ATOM   4502  C C   . PHE B 2 246 ? 122.308 113.012 140.828 1.00 40.48  ? 221 PHE B C   1 
ATOM   4503  O O   . PHE B 2 246 ? 121.867 113.696 141.758 1.00 45.00  ? 221 PHE B O   1 
ATOM   4504  C CB  . PHE B 2 246 ? 121.296 113.592 138.618 1.00 36.17  ? 221 PHE B CB  1 
ATOM   4505  C CG  . PHE B 2 246 ? 121.445 114.231 137.269 1.00 33.62  ? 221 PHE B CG  1 
ATOM   4506  C CD1 . PHE B 2 246 ? 121.258 115.593 137.109 1.00 34.30  ? 221 PHE B CD1 1 
ATOM   4507  C CD2 . PHE B 2 246 ? 121.757 113.470 136.158 1.00 33.56  ? 221 PHE B CD2 1 
ATOM   4508  C CE1 . PHE B 2 246 ? 121.392 116.183 135.870 1.00 35.02  ? 221 PHE B CE1 1 
ATOM   4509  C CE2 . PHE B 2 246 ? 121.891 114.055 134.918 1.00 35.42  ? 221 PHE B CE2 1 
ATOM   4510  C CZ  . PHE B 2 246 ? 121.707 115.412 134.773 1.00 34.93  ? 221 PHE B CZ  1 
ATOM   4511  N N   . ILE B 2 247 ? 122.560 111.708 140.957 1.00 39.77  ? 222 ILE B N   1 
ATOM   4512  C CA  . ILE B 2 247 ? 122.409 111.050 142.251 1.00 37.41  ? 222 ILE B CA  1 
ATOM   4513  C C   . ILE B 2 247 ? 123.340 111.682 143.274 1.00 38.76  ? 222 ILE B C   1 
ATOM   4514  O O   . ILE B 2 247 ? 122.918 112.072 144.368 1.00 36.56  ? 222 ILE B O   1 
ATOM   4515  C CB  . ILE B 2 247 ? 122.654 109.536 142.123 1.00 33.56  ? 222 ILE B CB  1 
ATOM   4516  C CG1 . ILE B 2 247 ? 121.561 108.892 141.270 1.00 33.74  ? 222 ILE B CG1 1 
ATOM   4517  C CG2 . ILE B 2 247 ? 122.716 108.890 143.494 1.00 42.15  ? 222 ILE B CG2 1 
ATOM   4518  C CD1 . ILE B 2 247 ? 120.218 108.824 141.956 1.00 30.36  ? 222 ILE B CD1 1 
ATOM   4519  N N   . LEU B 2 248 ? 124.623 111.802 142.929 1.00 40.75  ? 223 LEU B N   1 
ATOM   4520  C CA  . LEU B 2 248 ? 125.602 112.306 143.884 1.00 43.56  ? 223 LEU B CA  1 
ATOM   4521  C C   . LEU B 2 248 ? 125.523 113.817 144.057 1.00 44.11  ? 223 LEU B C   1 
ATOM   4522  O O   . LEU B 2 248 ? 125.856 114.328 145.131 1.00 48.88  ? 223 LEU B O   1 
ATOM   4523  C CB  . LEU B 2 248 ? 127.010 111.908 143.442 1.00 46.02  ? 223 LEU B CB  1 
ATOM   4524  C CG  . LEU B 2 248 ? 127.353 110.419 143.498 1.00 39.97  ? 223 LEU B CG  1 
ATOM   4525  C CD1 . LEU B 2 248 ? 128.822 110.209 143.189 1.00 45.37  ? 223 LEU B CD1 1 
ATOM   4526  C CD2 . LEU B 2 248 ? 127.001 109.833 144.854 1.00 34.25  ? 223 LEU B CD2 1 
ATOM   4527  N N   . GLN B 2 249 ? 125.105 114.546 143.025 1.00 40.81  ? 224 GLN B N   1 
ATOM   4528  C CA  . GLN B 2 249 ? 125.154 116.002 143.058 1.00 48.75  ? 224 GLN B CA  1 
ATOM   4529  C C   . GLN B 2 249 ? 123.828 116.644 143.435 1.00 48.52  ? 224 GLN B C   1 
ATOM   4530  O O   . GLN B 2 249 ? 123.826 117.710 144.058 1.00 52.12  ? 224 GLN B O   1 
ATOM   4531  C CB  . GLN B 2 249 ? 125.600 116.553 141.700 1.00 51.39  ? 224 GLN B CB  1 
ATOM   4532  C CG  . GLN B 2 249 ? 125.926 118.044 141.683 1.00 60.12  ? 224 GLN B CG  1 
ATOM   4533  C CD  . GLN B 2 249 ? 127.048 118.425 142.630 1.00 65.17  ? 224 GLN B CD  1 
ATOM   4534  O OE1 . GLN B 2 249 ? 127.880 117.596 142.997 1.00 57.14  ? 224 GLN B OE1 1 
ATOM   4535  N NE2 . GLN B 2 249 ? 127.077 119.691 143.028 1.00 68.67  ? 224 GLN B NE2 1 
ATOM   4536  N N   . THR B 2 250 ? 122.703 116.020 143.089 1.00 43.98  ? 225 THR B N   1 
ATOM   4537  C CA  . THR B 2 250 ? 121.392 116.617 143.321 1.00 39.38  ? 225 THR B CA  1 
ATOM   4538  C C   . THR B 2 250 ? 120.556 115.817 144.309 1.00 35.90  ? 225 THR B C   1 
ATOM   4539  O O   . THR B 2 250 ? 120.106 116.375 145.315 1.00 36.41  ? 225 THR B O   1 
ATOM   4540  C CB  . THR B 2 250 ? 120.640 116.762 141.992 1.00 42.75  ? 225 THR B CB  1 
ATOM   4541  O OG1 . THR B 2 250 ? 120.028 115.513 141.655 1.00 41.22  ? 225 THR B OG1 1 
ATOM   4542  C CG2 . THR B 2 250 ? 121.597 117.148 140.879 1.00 46.30  ? 225 THR B CG2 1 
ATOM   4543  N N   . TYR B 2 251 ? 120.323 114.528 144.056 1.00 35.29  ? 226 TYR B N   1 
ATOM   4544  C CA  . TYR B 2 251 ? 119.402 113.776 144.902 1.00 30.84  ? 226 TYR B CA  1 
ATOM   4545  C C   . TYR B 2 251 ? 120.007 113.484 146.269 1.00 35.05  ? 226 TYR B C   1 
ATOM   4546  O O   . TYR B 2 251 ? 119.343 113.668 147.296 1.00 34.37  ? 226 TYR B O   1 
ATOM   4547  C CB  . TYR B 2 251 ? 118.974 112.490 144.201 1.00 31.62  ? 226 TYR B CB  1 
ATOM   4548  C CG  . TYR B 2 251 ? 118.053 112.739 143.031 1.00 35.80  ? 226 TYR B CG  1 
ATOM   4549  C CD1 . TYR B 2 251 ? 116.701 112.969 143.232 1.00 35.99  ? 226 TYR B CD1 1 
ATOM   4550  C CD2 . TYR B 2 251 ? 118.532 112.747 141.730 1.00 37.36  ? 226 TYR B CD2 1 
ATOM   4551  C CE1 . TYR B 2 251 ? 115.852 113.200 142.174 1.00 35.77  ? 226 TYR B CE1 1 
ATOM   4552  C CE2 . TYR B 2 251 ? 117.688 112.976 140.663 1.00 40.43  ? 226 TYR B CE2 1 
ATOM   4553  C CZ  . TYR B 2 251 ? 116.349 113.202 140.893 1.00 39.68  ? 226 TYR B CZ  1 
ATOM   4554  O OH  . TYR B 2 251 ? 115.497 113.431 139.840 1.00 39.67  ? 226 TYR B OH  1 
ATOM   4555  N N   . MET B 2 252 ? 121.256 113.015 146.311 1.00 39.68  ? 227 MET B N   1 
ATOM   4556  C CA  . MET B 2 252 ? 121.851 112.682 147.605 1.00 34.29  ? 227 MET B CA  1 
ATOM   4557  C C   . MET B 2 252 ? 121.972 113.904 148.504 1.00 32.23  ? 227 MET B C   1 
ATOM   4558  O O   . MET B 2 252 ? 121.550 113.824 149.671 1.00 26.66  ? 227 MET B O   1 
ATOM   4559  C CB  . MET B 2 252 ? 123.206 111.988 147.425 1.00 32.13  ? 227 MET B CB  1 
ATOM   4560  C CG  . MET B 2 252 ? 124.044 111.975 148.700 1.00 31.11  ? 227 MET B CG  1 
ATOM   4561  S SD  . MET B 2 252 ? 125.696 111.282 148.504 1.00 45.84  ? 227 MET B SD  1 
ATOM   4562  C CE  . MET B 2 252 ? 126.555 112.661 147.757 1.00 33.86  ? 227 MET B CE  1 
ATOM   4563  N N   . PRO B 2 253 ? 122.540 115.037 148.063 1.00 32.10  ? 228 PRO B N   1 
ATOM   4564  C CA  . PRO B 2 253 ? 122.571 116.206 148.955 1.00 28.66  ? 228 PRO B CA  1 
ATOM   4565  C C   . PRO B 2 253 ? 121.191 116.636 149.409 1.00 28.45  ? 228 PRO B C   1 
ATOM   4566  O O   . PRO B 2 253 ? 121.016 117.005 150.575 1.00 30.12  ? 228 PRO B O   1 
ATOM   4567  C CB  . PRO B 2 253 ? 123.244 117.286 148.098 1.00 29.90  ? 228 PRO B CB  1 
ATOM   4568  C CG  . PRO B 2 253 ? 124.016 116.553 147.088 1.00 33.65  ? 228 PRO B CG  1 
ATOM   4569  C CD  . PRO B 2 253 ? 123.253 115.302 146.800 1.00 32.10  ? 228 PRO B CD  1 
ATOM   4570  N N   . SER B 2 254 ? 120.196 116.587 148.519 1.00 29.50  ? 229 SER B N   1 
ATOM   4571  C CA  . SER B 2 254 ? 118.851 116.988 148.911 1.00 27.07  ? 229 SER B CA  1 
ATOM   4572  C C   . SER B 2 254 ? 118.281 116.046 149.962 1.00 23.57  ? 229 SER B C   1 
ATOM   4573  O O   . SER B 2 254 ? 117.623 116.491 150.910 1.00 23.91  ? 229 SER B O   1 
ATOM   4574  C CB  . SER B 2 254 ? 117.945 117.034 147.684 1.00 26.34  ? 229 SER B CB  1 
ATOM   4575  O OG  . SER B 2 254 ? 118.444 117.949 146.727 1.00 30.34  ? 229 SER B OG  1 
ATOM   4576  N N   . ILE B 2 255 ? 118.506 114.740 149.803 1.00 23.28  ? 230 ILE B N   1 
ATOM   4577  C CA  . ILE B 2 255 ? 118.006 113.781 150.783 1.00 24.05  ? 230 ILE B CA  1 
ATOM   4578  C C   . ILE B 2 255 ? 118.676 114.017 152.129 1.00 27.20  ? 230 ILE B C   1 
ATOM   4579  O O   . ILE B 2 255 ? 118.020 114.039 153.177 1.00 28.68  ? 230 ILE B O   1 
ATOM   4580  C CB  . ILE B 2 255 ? 118.216 112.341 150.286 1.00 26.18  ? 230 ILE B CB  1 
ATOM   4581  C CG1 . ILE B 2 255 ? 117.302 112.051 149.097 1.00 27.39  ? 230 ILE B CG1 1 
ATOM   4582  C CG2 . ILE B 2 255 ? 117.938 111.350 151.398 1.00 20.93  ? 230 ILE B CG2 1 
ATOM   4583  C CD1 . ILE B 2 255 ? 117.673 110.804 148.335 1.00 29.01  ? 230 ILE B CD1 1 
ATOM   4584  N N   . LEU B 2 256 ? 120.001 114.191 152.118 1.00 26.12  ? 231 LEU B N   1 
ATOM   4585  C CA  . LEU B 2 256 ? 120.743 114.346 153.365 1.00 22.93  ? 231 LEU B CA  1 
ATOM   4586  C C   . LEU B 2 256 ? 120.358 115.633 154.083 1.00 22.45  ? 231 LEU B C   1 
ATOM   4587  O O   . LEU B 2 256 ? 120.262 115.654 155.314 1.00 25.07  ? 231 LEU B O   1 
ATOM   4588  C CB  . LEU B 2 256 ? 122.245 114.309 153.089 1.00 22.96  ? 231 LEU B CB  1 
ATOM   4589  C CG  . LEU B 2 256 ? 122.807 112.957 152.647 1.00 20.67  ? 231 LEU B CG  1 
ATOM   4590  C CD1 . LEU B 2 256 ? 124.320 113.011 152.546 1.00 22.55  ? 231 LEU B CD1 1 
ATOM   4591  C CD2 . LEU B 2 256 ? 122.375 111.864 153.606 1.00 15.25  ? 231 LEU B CD2 1 
ATOM   4592  N N   . ILE B 2 257 ? 120.144 116.721 153.336 1.00 23.55  ? 232 ILE B N   1 
ATOM   4593  C CA  . ILE B 2 257 ? 119.723 117.967 153.970 1.00 22.82  ? 232 ILE B CA  1 
ATOM   4594  C C   . ILE B 2 257 ? 118.346 117.794 154.591 1.00 23.91  ? 232 ILE B C   1 
ATOM   4595  O O   . ILE B 2 257 ? 118.082 118.273 155.700 1.00 23.85  ? 232 ILE B O   1 
ATOM   4596  C CB  . ILE B 2 257 ? 119.749 119.133 152.966 1.00 21.17  ? 232 ILE B CB  1 
ATOM   4597  C CG1 . ILE B 2 257 ? 121.173 119.397 152.484 1.00 20.62  ? 232 ILE B CG1 1 
ATOM   4598  C CG2 . ILE B 2 257 ? 119.195 120.392 153.606 1.00 22.20  ? 232 ILE B CG2 1 
ATOM   4599  C CD1 . ILE B 2 257 ? 122.122 119.755 153.590 1.00 24.57  ? 232 ILE B CD1 1 
ATOM   4600  N N   . THR B 2 258 ? 117.444 117.107 153.885 1.00 24.95  ? 233 THR B N   1 
ATOM   4601  C CA  . THR B 2 258 ? 116.119 116.863 154.441 1.00 25.14  ? 233 THR B CA  1 
ATOM   4602  C C   . THR B 2 258 ? 116.216 116.023 155.705 1.00 26.89  ? 233 THR B C   1 
ATOM   4603  O O   . THR B 2 258 ? 115.545 116.309 156.703 1.00 32.34  ? 233 THR B O   1 
ATOM   4604  C CB  . THR B 2 258 ? 115.231 116.177 153.404 1.00 27.70  ? 233 THR B CB  1 
ATOM   4605  O OG1 . THR B 2 258 ? 115.294 116.899 152.169 1.00 26.21  ? 233 THR B OG1 1 
ATOM   4606  C CG2 . THR B 2 258 ? 113.791 116.134 153.883 1.00 27.82  ? 233 THR B CG2 1 
ATOM   4607  N N   . ILE B 2 259 ? 117.051 114.980 155.683 1.00 22.90  ? 234 ILE B N   1 
ATOM   4608  C CA  . ILE B 2 259 ? 117.238 114.157 156.873 1.00 25.16  ? 234 ILE B CA  1 
ATOM   4609  C C   . ILE B 2 259 ? 117.885 114.980 157.976 1.00 27.31  ? 234 ILE B C   1 
ATOM   4610  O O   . ILE B 2 259 ? 117.579 114.815 159.162 1.00 34.01  ? 234 ILE B O   1 
ATOM   4611  C CB  . ILE B 2 259 ? 118.067 112.903 156.538 1.00 20.61  ? 234 ILE B CB  1 
ATOM   4612  C CG1 . ILE B 2 259 ? 117.316 112.009 155.553 1.00 25.11  ? 234 ILE B CG1 1 
ATOM   4613  C CG2 . ILE B 2 259 ? 118.399 112.122 157.795 1.00 14.68  ? 234 ILE B CG2 1 
ATOM   4614  C CD1 . ILE B 2 259 ? 118.156 110.887 154.998 1.00 25.43  ? 234 ILE B CD1 1 
ATOM   4615  N N   . LEU B 2 260 ? 118.787 115.889 157.598 1.00 24.79  ? 235 LEU B N   1 
ATOM   4616  C CA  . LEU B 2 260 ? 119.438 116.744 158.582 1.00 25.07  ? 235 LEU B CA  1 
ATOM   4617  C C   . LEU B 2 260 ? 118.435 117.679 159.243 1.00 28.51  ? 235 LEU B C   1 
ATOM   4618  O O   . LEU B 2 260 ? 118.556 117.986 160.433 1.00 34.02  ? 235 LEU B O   1 
ATOM   4619  C CB  . LEU B 2 260 ? 120.557 117.535 157.910 1.00 28.97  ? 235 LEU B CB  1 
ATOM   4620  C CG  . LEU B 2 260 ? 121.936 117.457 158.555 1.00 23.98  ? 235 LEU B CG  1 
ATOM   4621  C CD1 . LEU B 2 260 ? 122.249 116.030 158.958 1.00 20.88  ? 235 LEU B CD1 1 
ATOM   4622  C CD2 . LEU B 2 260 ? 122.988 117.981 157.594 1.00 16.02  ? 235 LEU B CD2 1 
ATOM   4623  N N   . SER B 2 261 ? 117.447 118.153 158.481 1.00 29.54  ? 236 SER B N   1 
ATOM   4624  C CA  . SER B 2 261 ? 116.429 119.030 159.047 1.00 29.24  ? 236 SER B CA  1 
ATOM   4625  C C   . SER B 2 261 ? 115.613 118.315 160.113 1.00 28.48  ? 236 SER B C   1 
ATOM   4626  O O   . SER B 2 261 ? 115.094 118.958 161.032 1.00 26.11  ? 236 SER B O   1 
ATOM   4627  C CB  . SER B 2 261 ? 115.515 119.557 157.944 1.00 24.02  ? 236 SER B CB  1 
ATOM   4628  O OG  . SER B 2 261 ? 114.825 118.498 157.308 1.00 23.60  ? 236 SER B OG  1 
ATOM   4629  N N   . TRP B 2 262 ? 115.494 116.988 160.009 1.00 25.77  ? 237 TRP B N   1 
ATOM   4630  C CA  . TRP B 2 262 ? 114.771 116.206 161.003 1.00 26.87  ? 237 TRP B CA  1 
ATOM   4631  C C   . TRP B 2 262 ? 115.507 116.124 162.330 1.00 33.60  ? 237 TRP B C   1 
ATOM   4632  O O   . TRP B 2 262 ? 114.905 115.716 163.328 1.00 42.29  ? 237 TRP B O   1 
ATOM   4633  C CB  . TRP B 2 262 ? 114.506 114.796 160.480 1.00 24.27  ? 237 TRP B CB  1 
ATOM   4634  C CG  . TRP B 2 262 ? 113.800 114.763 159.168 1.00 24.79  ? 237 TRP B CG  1 
ATOM   4635  C CD1 . TRP B 2 262 ? 113.041 115.754 158.619 1.00 27.92  ? 237 TRP B CD1 1 
ATOM   4636  C CD2 . TRP B 2 262 ? 113.782 113.680 158.234 1.00 26.85  ? 237 TRP B CD2 1 
ATOM   4637  N NE1 . TRP B 2 262 ? 112.556 115.356 157.398 1.00 30.55  ? 237 TRP B NE1 1 
ATOM   4638  C CE2 . TRP B 2 262 ? 112.996 114.085 157.140 1.00 30.98  ? 237 TRP B CE2 1 
ATOM   4639  C CE3 . TRP B 2 262 ? 114.355 112.406 158.218 1.00 27.15  ? 237 TRP B CE3 1 
ATOM   4640  C CZ2 . TRP B 2 262 ? 112.771 113.263 156.041 1.00 32.40  ? 237 TRP B CZ2 1 
ATOM   4641  C CZ3 . TRP B 2 262 ? 114.129 111.592 157.127 1.00 27.53  ? 237 TRP B CZ3 1 
ATOM   4642  C CH2 . TRP B 2 262 ? 113.344 112.023 156.054 1.00 31.16  ? 237 TRP B CH2 1 
ATOM   4643  N N   . VAL B 2 263 ? 116.794 116.477 162.364 1.00 30.65  ? 238 VAL B N   1 
ATOM   4644  C CA  . VAL B 2 263 ? 117.534 116.432 163.621 1.00 36.58  ? 238 VAL B CA  1 
ATOM   4645  C C   . VAL B 2 263 ? 116.895 117.363 164.641 1.00 44.16  ? 238 VAL B C   1 
ATOM   4646  O O   . VAL B 2 263 ? 116.959 117.113 165.852 1.00 50.24  ? 238 VAL B O   1 
ATOM   4647  C CB  . VAL B 2 263 ? 119.019 116.772 163.371 1.00 36.76  ? 238 VAL B CB  1 
ATOM   4648  C CG1 . VAL B 2 263 ? 119.745 117.073 164.670 1.00 35.84  ? 238 VAL B CG1 1 
ATOM   4649  C CG2 . VAL B 2 263 ? 119.703 115.635 162.633 1.00 35.98  ? 238 VAL B CG2 1 
ATOM   4650  N N   . SER B 2 264 ? 116.244 118.433 164.173 1.00 42.84  ? 239 SER B N   1 
ATOM   4651  C CA  . SER B 2 264 ? 115.584 119.356 165.088 1.00 43.35  ? 239 SER B CA  1 
ATOM   4652  C C   . SER B 2 264 ? 114.524 118.653 165.923 1.00 43.01  ? 239 SER B C   1 
ATOM   4653  O O   . SER B 2 264 ? 114.306 119.016 167.084 1.00 46.03  ? 239 SER B O   1 
ATOM   4654  C CB  . SER B 2 264 ? 114.961 120.511 164.304 1.00 44.14  ? 239 SER B CB  1 
ATOM   4655  O OG  . SER B 2 264 ? 114.292 121.415 165.165 1.00 49.18  ? 239 SER B OG  1 
ATOM   4656  N N   . PHE B 2 265 ? 113.857 117.646 165.354 1.00 39.80  ? 240 PHE B N   1 
ATOM   4657  C CA  . PHE B 2 265 ? 112.819 116.930 166.086 1.00 43.58  ? 240 PHE B CA  1 
ATOM   4658  C C   . PHE B 2 265 ? 113.380 116.163 167.274 1.00 45.07  ? 240 PHE B C   1 
ATOM   4659  O O   . PHE B 2 265 ? 112.618 115.776 168.167 1.00 50.01  ? 240 PHE B O   1 
ATOM   4660  C CB  . PHE B 2 265 ? 112.096 115.964 165.148 1.00 43.45  ? 240 PHE B CB  1 
ATOM   4661  C CG  . PHE B 2 265 ? 111.572 116.607 163.898 1.00 38.53  ? 240 PHE B CG  1 
ATOM   4662  C CD1 . PHE B 2 265 ? 111.104 117.909 163.911 1.00 43.20  ? 240 PHE B CD1 1 
ATOM   4663  C CD2 . PHE B 2 265 ? 111.566 115.914 162.702 1.00 31.78  ? 240 PHE B CD2 1 
ATOM   4664  C CE1 . PHE B 2 265 ? 110.627 118.498 162.760 1.00 38.20  ? 240 PHE B CE1 1 
ATOM   4665  C CE2 . PHE B 2 265 ? 111.093 116.500 161.551 1.00 30.02  ? 240 PHE B CE2 1 
ATOM   4666  C CZ  . PHE B 2 265 ? 110.623 117.793 161.580 1.00 31.78  ? 240 PHE B CZ  1 
ATOM   4667  N N   . TRP B 2 266 ? 114.690 115.931 167.300 1.00 42.50  ? 241 TRP B N   1 
ATOM   4668  C CA  . TRP B 2 266 ? 115.351 115.186 168.359 1.00 43.47  ? 241 TRP B CA  1 
ATOM   4669  C C   . TRP B 2 266 ? 116.065 116.093 169.352 1.00 47.39  ? 241 TRP B C   1 
ATOM   4670  O O   . TRP B 2 266 ? 116.755 115.595 170.247 1.00 44.84  ? 241 TRP B O   1 
ATOM   4671  C CB  . TRP B 2 266 ? 116.337 114.184 167.755 1.00 44.59  ? 241 TRP B CB  1 
ATOM   4672  C CG  . TRP B 2 266 ? 115.682 113.168 166.861 1.00 51.15  ? 241 TRP B CG  1 
ATOM   4673  C CD1 . TRP B 2 266 ? 115.336 113.333 165.551 1.00 49.93  ? 241 TRP B CD1 1 
ATOM   4674  C CD2 . TRP B 2 266 ? 115.276 111.842 167.218 1.00 51.27  ? 241 TRP B CD2 1 
ATOM   4675  N NE1 . TRP B 2 266 ? 114.753 112.188 165.067 1.00 47.91  ? 241 TRP B NE1 1 
ATOM   4676  C CE2 . TRP B 2 266 ? 114.702 111.258 166.071 1.00 50.06  ? 241 TRP B CE2 1 
ATOM   4677  C CE3 . TRP B 2 266 ? 115.346 111.090 168.394 1.00 47.81  ? 241 TRP B CE3 1 
ATOM   4678  C CZ2 . TRP B 2 266 ? 114.201 109.959 166.066 1.00 47.03  ? 241 TRP B CZ2 1 
ATOM   4679  C CZ3 . TRP B 2 266 ? 114.849 109.801 168.387 1.00 54.76  ? 241 TRP B CZ3 1 
ATOM   4680  C CH2 . TRP B 2 266 ? 114.283 109.249 167.231 1.00 50.29  ? 241 TRP B CH2 1 
ATOM   4681  N N   . ILE B 2 267 ? 115.919 117.408 169.213 1.00 51.04  ? 242 ILE B N   1 
ATOM   4682  C CA  . ILE B 2 267 ? 116.525 118.372 170.121 1.00 50.81  ? 242 ILE B CA  1 
ATOM   4683  C C   . ILE B 2 267 ? 115.457 118.901 171.068 1.00 53.98  ? 242 ILE B C   1 
ATOM   4684  O O   . ILE B 2 267 ? 114.270 118.964 170.727 1.00 52.34  ? 242 ILE B O   1 
ATOM   4685  C CB  . ILE B 2 267 ? 117.184 119.510 169.310 1.00 49.43  ? 242 ILE B CB  1 
ATOM   4686  C CG1 . ILE B 2 267 ? 118.241 118.937 168.365 1.00 47.52  ? 242 ILE B CG1 1 
ATOM   4687  C CG2 . ILE B 2 267 ? 117.834 120.540 170.220 1.00 53.15  ? 242 ILE B CG2 1 
ATOM   4688  C CD1 . ILE B 2 267 ? 118.798 119.943 167.390 1.00 43.43  ? 242 ILE B CD1 1 
ATOM   4689  N N   . ASN B 2 268 ? 115.883 119.276 172.274 1.00 60.65  ? 243 ASN B N   1 
ATOM   4690  C CA  . ASN B 2 268 ? 114.955 119.750 173.292 1.00 67.70  ? 243 ASN B CA  1 
ATOM   4691  C C   . ASN B 2 268 ? 114.218 120.994 172.813 1.00 70.08  ? 243 ASN B C   1 
ATOM   4692  O O   . ASN B 2 268 ? 114.785 121.843 172.121 1.00 66.86  ? 243 ASN B O   1 
ATOM   4693  C CB  . ASN B 2 268 ? 115.709 120.055 174.587 1.00 75.59  ? 243 ASN B CB  1 
ATOM   4694  C CG  . ASN B 2 268 ? 116.099 118.801 175.345 1.00 84.61  ? 243 ASN B CG  1 
ATOM   4695  O OD1 . ASN B 2 268 ? 115.473 117.752 175.196 1.00 83.83  ? 243 ASN B OD1 1 
ATOM   4696  N ND2 . ASN B 2 268 ? 117.141 118.904 176.160 1.00 80.84  ? 243 ASN B ND2 1 
ATOM   4697  N N   . TYR B 2 269 ? 112.936 121.093 173.179 1.00 76.92  ? 244 TYR B N   1 
ATOM   4698  C CA  . TYR B 2 269 ? 112.137 122.248 172.782 1.00 73.03  ? 244 TYR B CA  1 
ATOM   4699  C C   . TYR B 2 269 ? 112.724 123.556 173.300 1.00 72.33  ? 244 TYR B C   1 
ATOM   4700  O O   . TYR B 2 269 ? 112.562 124.603 172.663 1.00 71.19  ? 244 TYR B O   1 
ATOM   4701  C CB  . TYR B 2 269 ? 110.697 122.087 173.271 1.00 64.97  ? 244 TYR B CB  1 
ATOM   4702  C CG  . TYR B 2 269 ? 110.557 122.129 174.774 1.00 73.75  ? 244 TYR B CG  1 
ATOM   4703  C CD1 . TYR B 2 269 ? 110.760 120.991 175.542 1.00 80.63  ? 244 TYR B CD1 1 
ATOM   4704  C CD2 . TYR B 2 269 ? 110.231 123.309 175.426 1.00 76.15  ? 244 TYR B CD2 1 
ATOM   4705  C CE1 . TYR B 2 269 ? 110.637 121.026 176.916 1.00 90.38  ? 244 TYR B CE1 1 
ATOM   4706  C CE2 . TYR B 2 269 ? 110.107 123.355 176.799 1.00 83.86  ? 244 TYR B CE2 1 
ATOM   4707  C CZ  . TYR B 2 269 ? 110.311 122.211 177.540 1.00 91.73  ? 244 TYR B CZ  1 
ATOM   4708  O OH  . TYR B 2 269 ? 110.186 122.253 178.909 1.00 94.36  ? 244 TYR B OH  1 
ATOM   4709  N N   . ASP B 2 270 ? 113.409 123.517 174.443 1.00 74.76  ? 245 ASP B N   1 
ATOM   4710  C CA  . ASP B 2 270 ? 113.959 124.730 175.034 1.00 71.36  ? 245 ASP B CA  1 
ATOM   4711  C C   . ASP B 2 270 ? 115.196 125.237 174.308 1.00 68.83  ? 245 ASP B C   1 
ATOM   4712  O O   . ASP B 2 270 ? 115.574 126.398 174.496 1.00 72.28  ? 245 ASP B O   1 
ATOM   4713  C CB  . ASP B 2 270 ? 114.287 124.499 176.513 1.00 80.02  ? 245 ASP B CB  1 
ATOM   4714  C CG  . ASP B 2 270 ? 115.225 123.327 176.731 1.00 80.18  ? 245 ASP B CG  1 
ATOM   4715  O OD1 . ASP B 2 270 ? 116.447 123.497 176.542 1.00 73.20  ? 245 ASP B OD1 1 
ATOM   4716  O OD2 . ASP B 2 270 ? 114.739 122.237 177.098 1.00 85.02  ? 245 ASP B OD2 1 
ATOM   4717  N N   . ALA B 2 271 ? 115.834 124.402 173.486 1.00 69.28  ? 246 ALA B N   1 
ATOM   4718  C CA  . ALA B 2 271 ? 117.011 124.814 172.722 1.00 64.16  ? 246 ALA B CA  1 
ATOM   4719  C C   . ALA B 2 271 ? 116.575 125.570 171.467 1.00 51.03  ? 246 ALA B C   1 
ATOM   4720  O O   . ALA B 2 271 ? 116.706 125.105 170.333 1.00 49.70  ? 246 ALA B O   1 
ATOM   4721  C CB  . ALA B 2 271 ? 117.872 123.608 172.377 1.00 60.02  ? 246 ALA B CB  1 
ATOM   4722  N N   . SER B 2 272 ? 116.029 126.767 171.694 1.00 49.05  ? 247 SER B N   1 
ATOM   4723  C CA  . SER B 2 272 ? 115.498 127.549 170.583 1.00 45.89  ? 247 SER B CA  1 
ATOM   4724  C C   . SER B 2 272 ? 116.612 127.995 169.647 1.00 45.81  ? 247 SER B C   1 
ATOM   4725  O O   . SER B 2 272 ? 116.437 128.001 168.424 1.00 46.03  ? 247 SER B O   1 
ATOM   4726  C CB  . SER B 2 272 ? 114.729 128.759 171.110 1.00 46.11  ? 247 SER B CB  1 
ATOM   4727  O OG  . SER B 2 272 ? 115.604 129.697 171.707 1.00 51.90  ? 247 SER B OG  1 
ATOM   4728  N N   . ALA B 2 273 ? 117.768 128.364 170.203 1.00 42.84  ? 248 ALA B N   1 
ATOM   4729  C CA  . ALA B 2 273 ? 118.864 128.841 169.368 1.00 36.98  ? 248 ALA B CA  1 
ATOM   4730  C C   . ALA B 2 273 ? 119.419 127.725 168.494 1.00 36.31  ? 248 ALA B C   1 
ATOM   4731  O O   . ALA B 2 273 ? 119.810 127.966 167.347 1.00 31.65  ? 248 ALA B O   1 
ATOM   4732  C CB  . ALA B 2 273 ? 119.967 129.437 170.241 1.00 36.38  ? 248 ALA B CB  1 
ATOM   4733  N N   . ALA B 2 274 ? 119.455 126.496 169.014 1.00 43.91  ? 249 ALA B N   1 
ATOM   4734  C CA  . ALA B 2 274 ? 119.980 125.380 168.235 1.00 39.94  ? 249 ALA B CA  1 
ATOM   4735  C C   . ALA B 2 274 ? 119.002 124.936 167.156 1.00 35.86  ? 249 ALA B C   1 
ATOM   4736  O O   . ALA B 2 274 ? 119.406 124.672 166.018 1.00 33.17  ? 249 ALA B O   1 
ATOM   4737  C CB  . ALA B 2 274 ? 120.321 124.212 169.157 1.00 41.79  ? 249 ALA B CB  1 
ATOM   4738  N N   . ARG B 2 275 ? 117.712 124.847 167.488 1.00 35.10  ? 250 ARG B N   1 
ATOM   4739  C CA  . ARG B 2 275 ? 116.749 124.313 166.530 1.00 29.12  ? 250 ARG B CA  1 
ATOM   4740  C C   . ARG B 2 275 ? 116.447 125.317 165.425 1.00 27.75  ? 250 ARG B C   1 
ATOM   4741  O O   . ARG B 2 275 ? 116.242 124.932 164.269 1.00 26.60  ? 250 ARG B O   1 
ATOM   4742  C CB  . ARG B 2 275 ? 115.463 123.907 167.248 1.00 32.88  ? 250 ARG B CB  1 
ATOM   4743  C CG  . ARG B 2 275 ? 115.642 122.789 168.257 1.00 43.63  ? 250 ARG B CG  1 
ATOM   4744  C CD  . ARG B 2 275 ? 114.311 122.322 168.820 1.00 45.22  ? 250 ARG B CD  1 
ATOM   4745  N NE  . ARG B 2 275 ? 113.411 121.842 167.780 1.00 45.94  ? 250 ARG B NE  1 
ATOM   4746  C CZ  . ARG B 2 275 ? 112.307 121.145 168.009 1.00 47.18  ? 250 ARG B CZ  1 
ATOM   4747  N NH1 . ARG B 2 275 ? 111.957 120.790 169.234 1.00 50.79  ? 250 ARG B NH1 1 
ATOM   4748  N NH2 . ARG B 2 275 ? 111.544 120.782 166.983 1.00 45.39  ? 250 ARG B NH2 1 
ATOM   4749  N N   . VAL B 2 276 ? 116.413 126.608 165.760 1.00 27.59  ? 251 VAL B N   1 
ATOM   4750  C CA  . VAL B 2 276 ? 116.187 127.626 164.740 1.00 24.73  ? 251 VAL B CA  1 
ATOM   4751  C C   . VAL B 2 276 ? 117.398 127.755 163.825 1.00 27.51  ? 251 VAL B C   1 
ATOM   4752  O O   . VAL B 2 276 ? 117.257 127.827 162.599 1.00 27.53  ? 251 VAL B O   1 
ATOM   4753  C CB  . VAL B 2 276 ? 115.823 128.969 165.395 1.00 22.97  ? 251 VAL B CB  1 
ATOM   4754  C CG1 . VAL B 2 276 ? 115.802 130.072 164.362 1.00 21.49  ? 251 VAL B CG1 1 
ATOM   4755  C CG2 . VAL B 2 276 ? 114.470 128.867 166.075 1.00 22.34  ? 251 VAL B CG2 1 
ATOM   4756  N N   . ALA B 2 277 ? 118.605 127.779 164.399 1.00 27.76  ? 252 ALA B N   1 
ATOM   4757  C CA  . ALA B 2 277 ? 119.810 127.848 163.576 1.00 23.73  ? 252 ALA B CA  1 
ATOM   4758  C C   . ALA B 2 277 ? 119.929 126.637 162.662 1.00 24.48  ? 252 ALA B C   1 
ATOM   4759  O O   . ALA B 2 277 ? 120.272 126.772 161.483 1.00 25.36  ? 252 ALA B O   1 
ATOM   4760  C CB  . ALA B 2 277 ? 121.048 127.977 164.461 1.00 27.47  ? 252 ALA B CB  1 
ATOM   4761  N N   . LEU B 2 278 ? 119.661 125.442 163.191 1.00 23.42  ? 253 LEU B N   1 
ATOM   4762  C CA  . LEU B 2 278 ? 119.622 124.251 162.349 1.00 23.29  ? 253 LEU B CA  1 
ATOM   4763  C C   . LEU B 2 278 ? 118.554 124.381 161.271 1.00 24.80  ? 253 LEU B C   1 
ATOM   4764  O O   . LEU B 2 278 ? 118.805 124.105 160.093 1.00 25.31  ? 253 LEU B O   1 
ATOM   4765  C CB  . LEU B 2 278 ? 119.372 123.012 163.212 1.00 27.01  ? 253 LEU B CB  1 
ATOM   4766  C CG  . LEU B 2 278 ? 119.885 121.644 162.748 1.00 28.67  ? 253 LEU B CG  1 
ATOM   4767  C CD1 . LEU B 2 278 ? 119.707 120.633 163.862 1.00 33.54  ? 253 LEU B CD1 1 
ATOM   4768  C CD2 . LEU B 2 278 ? 119.194 121.156 161.484 1.00 22.30  ? 253 LEU B CD2 1 
ATOM   4769  N N   . GLY B 2 279 ? 117.350 124.803 161.661 1.00 25.17  ? 254 GLY B N   1 
ATOM   4770  C CA  . GLY B 2 279 ? 116.249 124.849 160.715 1.00 21.66  ? 254 GLY B CA  1 
ATOM   4771  C C   . GLY B 2 279 ? 116.433 125.874 159.613 1.00 24.23  ? 254 GLY B C   1 
ATOM   4772  O O   . GLY B 2 279 ? 116.190 125.581 158.440 1.00 26.80  ? 254 GLY B O   1 
ATOM   4773  N N   . ILE B 2 280 ? 116.871 127.085 159.964 1.00 23.84  ? 255 ILE B N   1 
ATOM   4774  C CA  . ILE B 2 280 ? 116.955 128.128 158.947 1.00 22.36  ? 255 ILE B CA  1 
ATOM   4775  C C   . ILE B 2 280 ? 118.188 127.949 158.070 1.00 22.26  ? 255 ILE B C   1 
ATOM   4776  O O   . ILE B 2 280 ? 118.163 128.301 156.885 1.00 22.90  ? 255 ILE B O   1 
ATOM   4777  C CB  . ILE B 2 280 ? 116.915 129.527 159.589 1.00 18.50  ? 255 ILE B CB  1 
ATOM   4778  C CG1 . ILE B 2 280 ? 116.696 130.593 158.514 1.00 17.10  ? 255 ILE B CG1 1 
ATOM   4779  C CG2 . ILE B 2 280 ? 118.195 129.822 160.346 1.00 21.39  ? 255 ILE B CG2 1 
ATOM   4780  C CD1 . ILE B 2 280 ? 115.399 130.438 157.756 1.00 18.99  ? 255 ILE B CD1 1 
ATOM   4781  N N   . THR B 2 281 ? 119.282 127.413 158.617 1.00 20.52  ? 256 THR B N   1 
ATOM   4782  C CA  . THR B 2 281 ? 120.459 127.176 157.790 1.00 21.41  ? 256 THR B CA  1 
ATOM   4783  C C   . THR B 2 281 ? 120.207 126.066 156.779 1.00 21.44  ? 256 THR B C   1 
ATOM   4784  O O   . THR B 2 281 ? 120.721 126.125 155.657 1.00 21.56  ? 256 THR B O   1 
ATOM   4785  C CB  . THR B 2 281 ? 121.669 126.854 158.660 1.00 22.19  ? 256 THR B CB  1 
ATOM   4786  O OG1 . THR B 2 281 ? 121.767 127.822 159.711 1.00 27.05  ? 256 THR B OG1 1 
ATOM   4787  C CG2 . THR B 2 281 ? 122.937 126.924 157.828 1.00 17.53  ? 256 THR B CG2 1 
ATOM   4788  N N   . THR B 2 282 ? 119.420 125.050 157.151 1.00 21.70  ? 257 THR B N   1 
ATOM   4789  C CA  . THR B 2 282 ? 119.038 124.031 156.179 1.00 22.36  ? 257 THR B CA  1 
ATOM   4790  C C   . THR B 2 282 ? 118.170 124.636 155.086 1.00 24.83  ? 257 THR B C   1 
ATOM   4791  O O   . THR B 2 282 ? 118.287 124.261 153.913 1.00 24.75  ? 257 THR B O   1 
ATOM   4792  C CB  . THR B 2 282 ? 118.313 122.877 156.867 1.00 20.91  ? 257 THR B CB  1 
ATOM   4793  O OG1 . THR B 2 282 ? 117.323 123.397 157.762 1.00 24.43  ? 257 THR B OG1 1 
ATOM   4794  C CG2 . THR B 2 282 ? 119.295 122.019 157.641 1.00 18.70  ? 257 THR B CG2 1 
ATOM   4795  N N   . VAL B 2 283 ? 117.277 125.557 155.455 1.00 22.66  ? 258 VAL B N   1 
ATOM   4796  C CA  . VAL B 2 283 ? 116.505 126.278 154.449 1.00 19.19  ? 258 VAL B CA  1 
ATOM   4797  C C   . VAL B 2 283 ? 117.450 127.068 153.557 1.00 21.78  ? 258 VAL B C   1 
ATOM   4798  O O   . VAL B 2 283 ? 117.302 127.092 152.330 1.00 25.87  ? 258 VAL B O   1 
ATOM   4799  C CB  . VAL B 2 283 ? 115.457 127.185 155.118 1.00 17.86  ? 258 VAL B CB  1 
ATOM   4800  C CG1 . VAL B 2 283 ? 114.825 128.107 154.094 1.00 20.97  ? 258 VAL B CG1 1 
ATOM   4801  C CG2 . VAL B 2 283 ? 114.395 126.347 155.803 1.00 20.86  ? 258 VAL B CG2 1 
ATOM   4802  N N   . LEU B 2 284 ? 118.436 127.732 154.167 1.00 20.51  ? 259 LEU B N   1 
ATOM   4803  C CA  . LEU B 2 284 ? 119.438 128.455 153.393 1.00 20.86  ? 259 LEU B CA  1 
ATOM   4804  C C   . LEU B 2 284 ? 120.244 127.500 152.525 1.00 22.70  ? 259 LEU B C   1 
ATOM   4805  O O   . LEU B 2 284 ? 120.518 127.794 151.357 1.00 24.43  ? 259 LEU B O   1 
ATOM   4806  C CB  . LEU B 2 284 ? 120.357 129.239 154.328 1.00 19.20  ? 259 LEU B CB  1 
ATOM   4807  C CG  . LEU B 2 284 ? 121.521 129.974 153.670 1.00 14.90  ? 259 LEU B CG  1 
ATOM   4808  C CD1 . LEU B 2 284 ? 121.013 130.964 152.642 1.00 16.87  ? 259 LEU B CD1 1 
ATOM   4809  C CD2 . LEU B 2 284 ? 122.363 130.672 154.722 1.00 16.46  ? 259 LEU B CD2 1 
ATOM   4810  N N   . THR B 2 285 ? 120.646 126.355 153.087 1.00 22.60  ? 260 THR B N   1 
ATOM   4811  C CA  . THR B 2 285 ? 121.401 125.379 152.308 1.00 22.01  ? 260 THR B CA  1 
ATOM   4812  C C   . THR B 2 285 ? 120.582 124.893 151.122 1.00 22.51  ? 260 THR B C   1 
ATOM   4813  O O   . THR B 2 285 ? 121.109 124.742 150.014 1.00 23.96  ? 260 THR B O   1 
ATOM   4814  C CB  . THR B 2 285 ? 121.827 124.207 153.188 1.00 20.86  ? 260 THR B CB  1 
ATOM   4815  O OG1 . THR B 2 285 ? 122.633 124.692 154.268 1.00 24.78  ? 260 THR B OG1 1 
ATOM   4816  C CG2 . THR B 2 285 ? 122.638 123.212 152.382 1.00 16.81  ? 260 THR B CG2 1 
ATOM   4817  N N   . MET B 2 286 ? 119.289 124.630 151.337 1.00 22.71  ? 261 MET B N   1 
ATOM   4818  C CA  . MET B 2 286 ? 118.460 124.117 150.252 1.00 23.07  ? 261 MET B CA  1 
ATOM   4819  C C   . MET B 2 286 ? 118.332 125.147 149.138 1.00 25.31  ? 261 MET B C   1 
ATOM   4820  O O   . MET B 2 286 ? 118.368 124.793 147.954 1.00 27.65  ? 261 MET B O   1 
ATOM   4821  C CB  . MET B 2 286 ? 117.083 123.711 150.774 1.00 22.62  ? 261 MET B CB  1 
ATOM   4822  C CG  . MET B 2 286 ? 116.265 122.904 149.775 1.00 27.55  ? 261 MET B CG  1 
ATOM   4823  S SD  . MET B 2 286 ? 116.992 121.323 149.311 1.00 32.72  ? 261 MET B SD  1 
ATOM   4824  C CE  . MET B 2 286 ? 116.902 120.447 150.864 1.00 33.69  ? 261 MET B CE  1 
ATOM   4825  N N   . THR B 2 287 ? 118.170 126.426 149.493 1.00 24.42  ? 262 THR B N   1 
ATOM   4826  C CA  . THR B 2 287 ? 118.124 127.444 148.452 1.00 25.29  ? 262 THR B CA  1 
ATOM   4827  C C   . THR B 2 287 ? 119.486 127.598 147.800 1.00 27.74  ? 262 THR B C   1 
ATOM   4828  O O   . THR B 2 287 ? 119.572 127.872 146.599 1.00 30.77  ? 262 THR B O   1 
ATOM   4829  C CB  . THR B 2 287 ? 117.674 128.787 149.022 1.00 21.32  ? 262 THR B CB  1 
ATOM   4830  O OG1 . THR B 2 287 ? 118.611 129.222 150.013 1.00 24.87  ? 262 THR B OG1 1 
ATOM   4831  C CG2 . THR B 2 287 ? 116.307 128.669 149.650 1.00 22.09  ? 262 THR B CG2 1 
ATOM   4832  N N   . THR B 2 288 ? 120.559 127.424 148.577 1.00 27.43  ? 263 THR B N   1 
ATOM   4833  C CA  . THR B 2 288 ? 121.896 127.469 148.002 1.00 27.11  ? 263 THR B CA  1 
ATOM   4834  C C   . THR B 2 288 ? 122.071 126.362 146.975 1.00 28.19  ? 263 THR B C   1 
ATOM   4835  O O   . THR B 2 288 ? 122.634 126.586 145.900 1.00 31.30  ? 263 THR B O   1 
ATOM   4836  C CB  . THR B 2 288 ? 122.952 127.362 149.101 1.00 26.53  ? 263 THR B CB  1 
ATOM   4837  O OG1 . THR B 2 288 ? 122.807 128.459 150.011 1.00 31.47  ? 263 THR B OG1 1 
ATOM   4838  C CG2 . THR B 2 288 ? 124.348 127.392 148.505 1.00 24.43  ? 263 THR B CG2 1 
ATOM   4839  N N   . ILE B 2 289 ? 121.589 125.157 147.289 1.00 27.68  ? 264 ILE B N   1 
ATOM   4840  C CA  . ILE B 2 289 ? 121.665 124.060 146.330 1.00 28.83  ? 264 ILE B CA  1 
ATOM   4841  C C   . ILE B 2 289 ? 120.851 124.390 145.089 1.00 34.72  ? 264 ILE B C   1 
ATOM   4842  O O   . ILE B 2 289 ? 121.326 124.251 143.958 1.00 37.26  ? 264 ILE B O   1 
ATOM   4843  C CB  . ILE B 2 289 ? 121.190 122.742 146.968 1.00 21.80  ? 264 ILE B CB  1 
ATOM   4844  C CG1 . ILE B 2 289 ? 122.161 122.276 148.049 1.00 19.42  ? 264 ILE B CG1 1 
ATOM   4845  C CG2 . ILE B 2 289 ? 121.033 121.666 145.910 1.00 22.52  ? 264 ILE B CG2 1 
ATOM   4846  C CD1 . ILE B 2 289 ? 121.619 121.161 148.908 1.00 23.01  ? 264 ILE B CD1 1 
ATOM   4847  N N   . ASN B 2 290 ? 119.616 124.856 145.282 1.00 34.35  ? 265 ASN B N   1 
ATOM   4848  C CA  . ASN B 2 290 ? 118.728 125.054 144.143 1.00 33.78  ? 265 ASN B CA  1 
ATOM   4849  C C   . ASN B 2 290 ? 119.177 126.222 143.270 1.00 39.25  ? 265 ASN B C   1 
ATOM   4850  O O   . ASN B 2 290 ? 119.139 126.128 142.039 1.00 43.08  ? 265 ASN B O   1 
ATOM   4851  C CB  . ASN B 2 290 ? 117.300 125.264 144.646 1.00 27.78  ? 265 ASN B CB  1 
ATOM   4852  C CG  . ASN B 2 290 ? 116.276 125.232 143.535 1.00 36.53  ? 265 ASN B CG  1 
ATOM   4853  O OD1 . ASN B 2 290 ? 116.425 124.502 142.557 1.00 43.56  ? 265 ASN B OD1 1 
ATOM   4854  N ND2 . ASN B 2 290 ? 115.217 126.017 143.686 1.00 39.45  ? 265 ASN B ND2 1 
ATOM   4855  N N   . THR B 2 291 ? 119.608 127.328 143.884 1.00 37.15  ? 266 THR B N   1 
ATOM   4856  C CA  . THR B 2 291 ? 120.026 128.494 143.106 1.00 36.40  ? 266 THR B CA  1 
ATOM   4857  C C   . THR B 2 291 ? 121.377 128.279 142.431 1.00 42.03  ? 266 THR B C   1 
ATOM   4858  O O   . THR B 2 291 ? 121.579 128.697 141.285 1.00 48.92  ? 266 THR B O   1 
ATOM   4859  C CB  . THR B 2 291 ? 120.065 129.738 143.993 1.00 34.31  ? 266 THR B CB  1 
ATOM   4860  O OG1 . THR B 2 291 ? 120.918 129.501 145.119 1.00 36.63  ? 266 THR B OG1 1 
ATOM   4861  C CG2 . THR B 2 291 ? 118.670 130.090 144.478 1.00 35.62  ? 266 THR B CG2 1 
ATOM   4862  N N   . HIS B 2 292 ? 122.312 127.626 143.125 1.00 41.29  ? 267 HIS B N   1 
ATOM   4863  C CA  . HIS B 2 292 ? 123.625 127.330 142.555 1.00 41.11  ? 267 HIS B CA  1 
ATOM   4864  C C   . HIS B 2 292 ? 123.580 126.188 141.550 1.00 43.24  ? 267 HIS B C   1 
ATOM   4865  O O   . HIS B 2 292 ? 124.395 126.155 140.622 1.00 46.82  ? 267 HIS B O   1 
ATOM   4866  C CB  . HIS B 2 292 ? 124.629 127.040 143.664 1.00 38.82  ? 267 HIS B CB  1 
ATOM   4867  C CG  . HIS B 2 292 ? 125.170 128.274 144.314 1.00 43.73  ? 267 HIS B CG  1 
ATOM   4868  N ND1 . HIS B 2 292 ? 124.606 128.828 145.442 1.00 43.75  ? 267 HIS B ND1 1 
ATOM   4869  C CD2 . HIS B 2 292 ? 126.218 129.067 143.989 1.00 45.36  ? 267 HIS B CD2 1 
ATOM   4870  C CE1 . HIS B 2 292 ? 125.285 129.907 145.787 1.00 43.54  ? 267 HIS B CE1 1 
ATOM   4871  N NE2 . HIS B 2 292 ? 126.269 130.074 144.922 1.00 46.33  ? 267 HIS B NE2 1 
ATOM   4872  N N   . LEU B 2 293 ? 122.651 125.253 141.707 1.00 44.56  ? 268 LEU B N   1 
ATOM   4873  C CA  . LEU B 2 293 ? 122.466 124.224 140.696 1.00 49.80  ? 268 LEU B CA  1 
ATOM   4874  C C   . LEU B 2 293 ? 121.497 124.666 139.613 1.00 53.61  ? 268 LEU B C   1 
ATOM   4875  O O   . LEU B 2 293 ? 121.380 123.991 138.589 1.00 54.71  ? 268 LEU B O   1 
ATOM   4876  C CB  . LEU B 2 293 ? 121.948 122.938 141.350 1.00 46.48  ? 268 LEU B CB  1 
ATOM   4877  C CG  . LEU B 2 293 ? 121.882 121.613 140.597 1.00 51.01  ? 268 LEU B CG  1 
ATOM   4878  C CD1 . LEU B 2 293 ? 123.271 121.075 140.309 1.00 57.01  ? 268 LEU B CD1 1 
ATOM   4879  C CD2 . LEU B 2 293 ? 121.066 120.622 141.400 1.00 51.74  ? 268 LEU B CD2 1 
ATOM   4880  N N   . ARG B 2 294 ? 120.828 125.800 139.807 1.00 55.13  ? 269 ARG B N   1 
ATOM   4881  C CA  . ARG B 2 294 ? 120.030 126.402 138.748 1.00 54.03  ? 269 ARG B CA  1 
ATOM   4882  C C   . ARG B 2 294 ? 120.925 126.925 137.632 1.00 53.33  ? 269 ARG B C   1 
ATOM   4883  O O   . ARG B 2 294 ? 120.561 126.856 136.453 1.00 55.26  ? 269 ARG B O   1 
ATOM   4884  C CB  . ARG B 2 294 ? 119.152 127.517 139.318 1.00 55.29  ? 269 ARG B CB  1 
ATOM   4885  C CG  . ARG B 2 294 ? 118.298 128.253 138.302 1.00 62.54  ? 269 ARG B CG  1 
ATOM   4886  C CD  . ARG B 2 294 ? 117.517 129.370 138.977 1.00 65.70  ? 269 ARG B CD  1 
ATOM   4887  N NE  . ARG B 2 294 ? 116.668 130.099 138.044 1.00 68.32  ? 269 ARG B NE  1 
ATOM   4888  C CZ  . ARG B 2 294 ? 115.882 131.112 138.383 1.00 71.26  ? 269 ARG B CZ  1 
ATOM   4889  N NH1 . ARG B 2 294 ? 115.815 131.546 139.630 1.00 74.82  ? 269 ARG B NH1 1 
ATOM   4890  N NH2 . ARG B 2 294 ? 115.142 131.701 137.448 1.00 72.14  ? 269 ARG B NH2 1 
ATOM   4891  N N   . GLU B 2 295 ? 122.104 127.445 137.991 1.00 53.39  ? 270 GLU B N   1 
ATOM   4892  C CA  . GLU B 2 295 ? 123.050 127.935 136.995 1.00 56.48  ? 270 GLU B CA  1 
ATOM   4893  C C   . GLU B 2 295 ? 123.922 126.838 136.392 1.00 55.86  ? 270 GLU B C   1 
ATOM   4894  O O   . GLU B 2 295 ? 124.371 126.988 135.250 1.00 55.30  ? 270 GLU B O   1 
ATOM   4895  C CB  . GLU B 2 295 ? 123.951 128.999 137.624 1.00 55.49  ? 270 GLU B CB  1 
ATOM   4896  C CG  . GLU B 2 295 ? 123.285 129.801 138.732 1.00 60.49  ? 270 GLU B CG  1 
ATOM   4897  C CD  . GLU B 2 295 ? 124.059 131.052 139.097 1.00 75.75  ? 270 GLU B CD  1 
ATOM   4898  O OE1 . GLU B 2 295 ? 125.229 131.172 138.677 1.00 80.98  ? 270 GLU B OE1 1 
ATOM   4899  O OE2 . GLU B 2 295 ? 123.501 131.913 139.809 1.00 73.79  ? 270 GLU B OE2 1 
ATOM   4900  N N   . THR B 2 296 ? 124.186 125.737 137.105 1.00 56.66  ? 271 THR B N   1 
ATOM   4901  C CA  . THR B 2 296 ? 124.952 124.680 136.449 1.00 56.09  ? 271 THR B CA  1 
ATOM   4902  C C   . THR B 2 296 ? 124.060 123.897 135.496 1.00 54.74  ? 271 THR B C   1 
ATOM   4903  O O   . THR B 2 296 ? 124.491 123.512 134.404 1.00 48.16  ? 271 THR B O   1 
ATOM   4904  C CB  . THR B 2 296 ? 125.572 123.747 137.487 1.00 54.01  ? 271 THR B CB  1 
ATOM   4905  O OG1 . THR B 2 296 ? 124.534 123.025 138.158 1.00 54.21  ? 271 THR B OG1 1 
ATOM   4906  C CG2 . THR B 2 296 ? 126.355 124.546 138.512 1.00 52.72  ? 271 THR B CG2 1 
ATOM   4907  N N   . LEU B 2 297 ? 122.817 123.666 135.901 1.00 60.59  ? 272 LEU B N   1 
ATOM   4908  C CA  . LEU B 2 297 ? 121.850 122.953 135.094 1.00 60.44  ? 272 LEU B CA  1 
ATOM   4909  C C   . LEU B 2 297 ? 121.415 123.898 133.981 1.00 62.79  ? 272 LEU B C   1 
ATOM   4910  O O   . LEU B 2 297 ? 121.608 125.111 134.089 1.00 63.70  ? 272 LEU B O   1 
ATOM   4911  C CB  . LEU B 2 297 ? 120.661 122.487 135.932 1.00 58.51  ? 272 LEU B CB  1 
ATOM   4912  C CG  . LEU B 2 297 ? 120.919 121.419 136.997 1.00 50.12  ? 272 LEU B CG  1 
ATOM   4913  C CD1 . LEU B 2 297 ? 119.626 121.068 137.714 1.00 43.33  ? 272 LEU B CD1 1 
ATOM   4914  C CD2 . LEU B 2 297 ? 121.552 120.181 136.389 1.00 44.44  ? 272 LEU B CD2 1 
ATOM   4915  N N   . PRO B 2 298 ? 120.833 123.395 132.902 1.00 65.14  ? 273 PRO B N   1 
ATOM   4916  C CA  . PRO B 2 298 ? 120.590 124.268 131.755 1.00 71.20  ? 273 PRO B CA  1 
ATOM   4917  C C   . PRO B 2 298 ? 119.372 125.142 132.029 1.00 74.51  ? 273 PRO B C   1 
ATOM   4918  O O   . PRO B 2 298 ? 118.533 124.855 132.884 1.00 71.60  ? 273 PRO B O   1 
ATOM   4919  C CB  . PRO B 2 298 ? 120.363 123.283 130.609 1.00 68.88  ? 273 PRO B CB  1 
ATOM   4920  C CG  . PRO B 2 298 ? 119.768 122.109 131.271 1.00 63.53  ? 273 PRO B CG  1 
ATOM   4921  C CD  . PRO B 2 298 ? 120.444 122.003 132.611 1.00 56.98  ? 273 PRO B CD  1 
ATOM   4922  N N   . LYS B 2 299 ? 119.297 126.231 131.272 1.00 76.57  ? 274 LYS B N   1 
ATOM   4923  C CA  . LYS B 2 299 ? 118.109 127.068 131.161 1.00 71.56  ? 274 LYS B CA  1 
ATOM   4924  C C   . LYS B 2 299 ? 116.897 126.465 130.466 1.00 65.96  ? 274 LYS B C   1 
ATOM   4925  O O   . LYS B 2 299 ? 116.535 126.903 129.369 1.00 66.62  ? 274 LYS B O   1 
ATOM   4926  C CB  . LYS B 2 299 ? 118.483 128.375 130.456 1.00 73.20  ? 274 LYS B CB  1 
ATOM   4927  C CG  . LYS B 2 299 ? 119.406 129.266 131.275 1.00 73.53  ? 274 LYS B CG  1 
ATOM   4928  C CD  . LYS B 2 299 ? 119.619 130.616 130.607 1.00 83.87  ? 274 LYS B CD  1 
ATOM   4929  C CE  . LYS B 2 299 ? 120.421 131.552 131.501 1.00 87.22  ? 274 LYS B CE  1 
ATOM   4930  N NZ  . LYS B 2 299 ? 120.498 132.931 130.944 1.00 88.84  ? 274 LYS B NZ  1 
ATOM   4931  N N   . ILE B 2 300 ? 116.285 125.445 131.063 1.00 63.50  ? 275 ILE B N   1 
ATOM   4932  C CA  . ILE B 2 300 ? 115.053 124.912 130.489 1.00 62.36  ? 275 ILE B CA  1 
ATOM   4933  C C   . ILE B 2 300 ? 113.911 125.456 131.339 1.00 57.50  ? 275 ILE B C   1 
ATOM   4934  O O   . ILE B 2 300 ? 113.611 124.897 132.404 1.00 59.03  ? 275 ILE B O   1 
ATOM   4935  C CB  . ILE B 2 300 ? 115.031 123.377 130.488 1.00 60.28  ? 275 ILE B CB  1 
ATOM   4936  C CG1 . ILE B 2 300 ? 116.258 122.798 129.795 1.00 62.09  ? 275 ILE B CG1 1 
ATOM   4937  C CG2 . ILE B 2 300 ? 113.773 122.865 129.822 1.00 58.90  ? 275 ILE B CG2 1 
ATOM   4938  C CD1 . ILE B 2 300 ? 116.570 121.405 130.273 1.00 62.12  ? 275 ILE B CD1 1 
ATOM   4939  N N   . PRO B 2 301 ? 113.253 126.533 130.917 1.00 52.95  ? 276 PRO B N   1 
ATOM   4940  C CA  . PRO B 2 301 ? 112.277 127.235 131.779 1.00 53.17  ? 276 PRO B CA  1 
ATOM   4941  C C   . PRO B 2 301 ? 110.901 126.579 131.800 1.00 55.94  ? 276 PRO B C   1 
ATOM   4942  O O   . PRO B 2 301 ? 109.910 127.120 131.296 1.00 55.19  ? 276 PRO B O   1 
ATOM   4943  C CB  . PRO B 2 301 ? 112.255 128.637 131.164 1.00 54.62  ? 276 PRO B CB  1 
ATOM   4944  C CG  . PRO B 2 301 ? 112.538 128.397 129.733 1.00 61.06  ? 276 PRO B CG  1 
ATOM   4945  C CD  . PRO B 2 301 ? 113.509 127.266 129.668 1.00 58.70  ? 276 PRO B CD  1 
ATOM   4946  N N   . TYR B 2 302 ? 110.810 125.400 132.409 1.00 56.28  ? 277 TYR B N   1 
ATOM   4947  C CA  . TYR B 2 302 ? 109.521 124.858 132.825 1.00 50.80  ? 277 TYR B CA  1 
ATOM   4948  C C   . TYR B 2 302 ? 109.752 123.755 133.845 1.00 47.04  ? 277 TYR B C   1 
ATOM   4949  O O   . TYR B 2 302 ? 110.874 123.284 134.044 1.00 45.55  ? 277 TYR B O   1 
ATOM   4950  C CB  . TYR B 2 302 ? 108.683 124.357 131.641 1.00 52.19  ? 277 TYR B CB  1 
ATOM   4951  C CG  . TYR B 2 302 ? 109.373 123.418 130.683 1.00 53.26  ? 277 TYR B CG  1 
ATOM   4952  C CD1 . TYR B 2 302 ? 109.417 122.052 130.925 1.00 51.41  ? 277 TYR B CD1 1 
ATOM   4953  C CD2 . TYR B 2 302 ? 109.935 123.892 129.506 1.00 46.26  ? 277 TYR B CD2 1 
ATOM   4954  C CE1 . TYR B 2 302 ? 110.032 121.191 130.039 1.00 49.12  ? 277 TYR B CE1 1 
ATOM   4955  C CE2 . TYR B 2 302 ? 110.546 123.039 128.613 1.00 46.96  ? 277 TYR B CE2 1 
ATOM   4956  C CZ  . TYR B 2 302 ? 110.593 121.690 128.884 1.00 49.48  ? 277 TYR B CZ  1 
ATOM   4957  O OH  . TYR B 2 302 ? 111.205 120.840 127.995 1.00 51.56  ? 277 TYR B OH  1 
ATOM   4958  N N   . VAL B 2 303 ? 108.661 123.350 134.491 1.00 45.26  ? 278 VAL B N   1 
ATOM   4959  C CA  . VAL B 2 303 ? 108.735 122.497 135.671 1.00 44.69  ? 278 VAL B CA  1 
ATOM   4960  C C   . VAL B 2 303 ? 109.129 121.089 135.248 1.00 48.24  ? 278 VAL B C   1 
ATOM   4961  O O   . VAL B 2 303 ? 108.402 120.420 134.505 1.00 52.05  ? 278 VAL B O   1 
ATOM   4962  C CB  . VAL B 2 303 ? 107.403 122.495 136.428 1.00 43.02  ? 278 VAL B CB  1 
ATOM   4963  C CG1 . VAL B 2 303 ? 107.533 121.701 137.707 1.00 42.19  ? 278 VAL B CG1 1 
ATOM   4964  C CG2 . VAL B 2 303 ? 106.959 123.919 136.718 1.00 47.35  ? 278 VAL B CG2 1 
ATOM   4965  N N   . LYS B 2 304 ? 110.281 120.632 135.727 1.00 45.86  ? 279 LYS B N   1 
ATOM   4966  C CA  . LYS B 2 304 ? 110.807 119.311 135.429 1.00 40.87  ? 279 LYS B CA  1 
ATOM   4967  C C   . LYS B 2 304 ? 110.750 118.437 136.675 1.00 40.12  ? 279 LYS B C   1 
ATOM   4968  O O   . LYS B 2 304 ? 110.404 118.893 137.767 1.00 43.67  ? 279 LYS B O   1 
ATOM   4969  C CB  . LYS B 2 304 ? 112.251 119.415 134.929 1.00 36.02  ? 279 LYS B CB  1 
ATOM   4970  C CG  . LYS B 2 304 ? 112.434 120.362 133.763 1.00 40.78  ? 279 LYS B CG  1 
ATOM   4971  C CD  . LYS B 2 304 ? 113.904 120.573 133.460 1.00 47.31  ? 279 LYS B CD  1 
ATOM   4972  C CE  . LYS B 2 304 ? 114.563 121.439 134.518 1.00 43.89  ? 279 LYS B CE  1 
ATOM   4973  N NZ  . LYS B 2 304 ? 113.997 122.815 134.537 1.00 40.86  ? 279 LYS B NZ  1 
ATOM   4974  N N   . ALA B 2 305 ? 111.080 117.155 136.495 1.00 39.01  ? 280 ALA B N   1 
ATOM   4975  C CA  . ALA B 2 305 ? 111.041 116.227 137.620 1.00 36.75  ? 280 ALA B CA  1 
ATOM   4976  C C   . ALA B 2 305 ? 112.035 116.637 138.697 1.00 36.86  ? 280 ALA B C   1 
ATOM   4977  O O   . ALA B 2 305 ? 111.765 116.485 139.894 1.00 44.59  ? 280 ALA B O   1 
ATOM   4978  C CB  . ALA B 2 305 ? 111.321 114.803 137.146 1.00 36.32  ? 280 ALA B CB  1 
ATOM   4979  N N   . ILE B 2 306 ? 113.199 117.145 138.289 1.00 35.15  ? 281 ILE B N   1 
ATOM   4980  C CA  . ILE B 2 306 ? 114.199 117.582 139.257 1.00 32.38  ? 281 ILE B CA  1 
ATOM   4981  C C   . ILE B 2 306 ? 113.676 118.767 140.058 1.00 30.07  ? 281 ILE B C   1 
ATOM   4982  O O   . ILE B 2 306 ? 113.916 118.872 141.266 1.00 31.66  ? 281 ILE B O   1 
ATOM   4983  C CB  . ILE B 2 306 ? 115.537 117.892 138.556 1.00 38.38  ? 281 ILE B CB  1 
ATOM   4984  C CG1 . ILE B 2 306 ? 116.636 118.142 139.590 1.00 37.08  ? 281 ILE B CG1 1 
ATOM   4985  C CG2 . ILE B 2 306 ? 115.407 119.056 137.582 1.00 37.65  ? 281 ILE B CG2 1 
ATOM   4986  C CD1 . ILE B 2 306 ? 116.890 116.964 140.501 1.00 37.04  ? 281 ILE B CD1 1 
ATOM   4987  N N   . ASP B 2 307 ? 112.954 119.679 139.398 1.00 33.68  ? 282 ASP B N   1 
ATOM   4988  C CA  . ASP B 2 307 ? 112.375 120.817 140.102 1.00 35.15  ? 282 ASP B CA  1 
ATOM   4989  C C   . ASP B 2 307 ? 111.396 120.358 141.171 1.00 36.14  ? 282 ASP B C   1 
ATOM   4990  O O   . ASP B 2 307 ? 111.385 120.899 142.281 1.00 37.47  ? 282 ASP B O   1 
ATOM   4991  C CB  . ASP B 2 307 ? 111.692 121.760 139.114 1.00 39.31  ? 282 ASP B CB  1 
ATOM   4992  C CG  . ASP B 2 307 ? 112.659 122.345 138.105 1.00 52.95  ? 282 ASP B CG  1 
ATOM   4993  O OD1 . ASP B 2 307 ? 113.844 122.528 138.454 1.00 53.77  ? 282 ASP B OD1 1 
ATOM   4994  O OD2 . ASP B 2 307 ? 112.235 122.624 136.964 1.00 63.26  ? 282 ASP B OD2 1 
ATOM   4995  N N   . MET B 2 308 ? 110.551 119.372 140.851 1.00 35.31  ? 283 MET B N   1 
ATOM   4996  C CA  . MET B 2 308 ? 109.564 118.915 141.823 1.00 28.92  ? 283 MET B CA  1 
ATOM   4997  C C   . MET B 2 308 ? 110.242 118.321 143.049 1.00 30.66  ? 283 MET B C   1 
ATOM   4998  O O   . MET B 2 308 ? 109.812 118.562 144.183 1.00 31.97  ? 283 MET B O   1 
ATOM   4999  C CB  . MET B 2 308 ? 108.617 117.899 141.187 1.00 31.01  ? 283 MET B CB  1 
ATOM   5000  C CG  . MET B 2 308 ? 107.850 118.435 140.001 1.00 38.06  ? 283 MET B CG  1 
ATOM   5001  S SD  . MET B 2 308 ? 106.754 119.775 140.501 1.00 79.20  ? 283 MET B SD  1 
ATOM   5002  C CE  . MET B 2 308 ? 105.436 118.862 141.295 1.00 51.59  ? 283 MET B CE  1 
ATOM   5003  N N   . TYR B 2 309 ? 111.307 117.542 142.843 1.00 32.71  ? 284 TYR B N   1 
ATOM   5004  C CA  . TYR B 2 309 ? 111.970 116.915 143.979 1.00 29.89  ? 284 TYR B CA  1 
ATOM   5005  C C   . TYR B 2 309 ? 112.666 117.962 144.835 1.00 29.44  ? 284 TYR B C   1 
ATOM   5006  O O   . TYR B 2 309 ? 112.609 117.904 146.068 1.00 33.11  ? 284 TYR B O   1 
ATOM   5007  C CB  . TYR B 2 309 ? 112.965 115.862 143.500 1.00 30.86  ? 284 TYR B CB  1 
ATOM   5008  C CG  . TYR B 2 309 ? 113.376 114.894 144.581 1.00 32.21  ? 284 TYR B CG  1 
ATOM   5009  C CD1 . TYR B 2 309 ? 112.614 113.768 144.850 1.00 38.29  ? 284 TYR B CD1 1 
ATOM   5010  C CD2 . TYR B 2 309 ? 114.514 115.112 145.341 1.00 30.04  ? 284 TYR B CD2 1 
ATOM   5011  C CE1 . TYR B 2 309 ? 112.978 112.881 145.836 1.00 36.81  ? 284 TYR B CE1 1 
ATOM   5012  C CE2 . TYR B 2 309 ? 114.885 114.229 146.332 1.00 34.77  ? 284 TYR B CE2 1 
ATOM   5013  C CZ  . TYR B 2 309 ? 114.113 113.115 146.575 1.00 34.68  ? 284 TYR B CZ  1 
ATOM   5014  O OH  . TYR B 2 309 ? 114.475 112.229 147.560 1.00 35.54  ? 284 TYR B OH  1 
ATOM   5015  N N   . LEU B 2 310 ? 113.341 118.921 144.196 1.00 29.26  ? 285 LEU B N   1 
ATOM   5016  C CA  . LEU B 2 310 ? 113.973 119.996 144.949 1.00 26.41  ? 285 LEU B CA  1 
ATOM   5017  C C   . LEU B 2 310 ? 112.917 120.838 145.650 1.00 31.64  ? 285 LEU B C   1 
ATOM   5018  O O   . LEU B 2 310 ? 113.099 121.249 146.801 1.00 32.03  ? 285 LEU B O   1 
ATOM   5019  C CB  . LEU B 2 310 ? 114.828 120.860 144.022 1.00 24.30  ? 285 LEU B CB  1 
ATOM   5020  C CG  . LEU B 2 310 ? 116.027 120.181 143.358 1.00 25.47  ? 285 LEU B CG  1 
ATOM   5021  C CD1 . LEU B 2 310 ? 116.767 121.155 142.457 1.00 30.98  ? 285 LEU B CD1 1 
ATOM   5022  C CD2 . LEU B 2 310 ? 116.962 119.603 144.401 1.00 21.59  ? 285 LEU B CD2 1 
ATOM   5023  N N   . MET B 2 311 ? 111.811 121.118 144.956 1.00 34.90  ? 286 MET B N   1 
ATOM   5024  C CA  . MET B 2 311 ? 110.723 121.873 145.565 1.00 34.89  ? 286 MET B CA  1 
ATOM   5025  C C   . MET B 2 311 ? 110.122 121.090 146.725 1.00 33.43  ? 286 MET B C   1 
ATOM   5026  O O   . MET B 2 311 ? 109.804 121.660 147.774 1.00 37.59  ? 286 MET B O   1 
ATOM   5027  C CB  . MET B 2 311 ? 109.655 122.183 144.517 1.00 35.40  ? 286 MET B CB  1 
ATOM   5028  C CG  . MET B 2 311 ? 108.566 123.146 144.954 1.00 39.38  ? 286 MET B CG  1 
ATOM   5029  S SD  . MET B 2 311 ? 109.220 124.753 145.445 1.00 77.27  ? 286 MET B SD  1 
ATOM   5030  C CE  . MET B 2 311 ? 109.048 124.666 147.217 1.00 52.80  ? 286 MET B CE  1 
ATOM   5031  N N   . GLY B 2 312 ? 109.949 119.778 146.543 1.00 28.22  ? 287 GLY B N   1 
ATOM   5032  C CA  . GLY B 2 312 ? 109.413 118.953 147.613 1.00 26.92  ? 287 GLY B CA  1 
ATOM   5033  C C   . GLY B 2 312 ? 110.296 118.949 148.846 1.00 31.13  ? 287 GLY B C   1 
ATOM   5034  O O   . GLY B 2 312 ? 109.808 119.059 149.972 1.00 32.84  ? 287 GLY B O   1 
ATOM   5035  N N   . CYS B 2 313 ? 111.609 118.806 148.650 1.00 33.15  ? 288 CYS B N   1 
ATOM   5036  C CA  . CYS B 2 313 ? 112.530 118.828 149.781 1.00 30.96  ? 288 CYS B CA  1 
ATOM   5037  C C   . CYS B 2 313 ? 112.523 120.190 150.461 1.00 32.76  ? 288 CYS B C   1 
ATOM   5038  O O   . CYS B 2 313 ? 112.644 120.281 151.687 1.00 34.63  ? 288 CYS B O   1 
ATOM   5039  C CB  . CYS B 2 313 ? 113.941 118.464 149.321 1.00 30.18  ? 288 CYS B CB  1 
ATOM   5040  S SG  . CYS B 2 313 ? 114.133 116.757 148.765 1.00 36.24  ? 288 CYS B SG  1 
ATOM   5041  N N   . PHE B 2 314 ? 112.397 121.263 149.675 1.00 32.52  ? 289 PHE B N   1 
ATOM   5042  C CA  . PHE B 2 314 ? 112.331 122.597 150.259 1.00 29.51  ? 289 PHE B CA  1 
ATOM   5043  C C   . PHE B 2 314 ? 111.094 122.749 151.133 1.00 28.93  ? 289 PHE B C   1 
ATOM   5044  O O   . PHE B 2 314 ? 111.133 123.428 152.164 1.00 29.91  ? 289 PHE B O   1 
ATOM   5045  C CB  . PHE B 2 314 ? 112.355 123.662 149.163 1.00 28.13  ? 289 PHE B CB  1 
ATOM   5046  C CG  . PHE B 2 314 ? 112.345 125.067 149.692 1.00 31.28  ? 289 PHE B CG  1 
ATOM   5047  C CD1 . PHE B 2 314 ? 113.520 125.672 150.097 1.00 29.24  ? 289 PHE B CD1 1 
ATOM   5048  C CD2 . PHE B 2 314 ? 111.166 125.784 149.784 1.00 32.75  ? 289 PHE B CD2 1 
ATOM   5049  C CE1 . PHE B 2 314 ? 113.517 126.959 150.590 1.00 25.20  ? 289 PHE B CE1 1 
ATOM   5050  C CE2 . PHE B 2 314 ? 111.161 127.075 150.275 1.00 34.49  ? 289 PHE B CE2 1 
ATOM   5051  C CZ  . PHE B 2 314 ? 112.338 127.663 150.676 1.00 26.62  ? 289 PHE B CZ  1 
ATOM   5052  N N   . VAL B 2 315 ? 109.976 122.146 150.724 1.00 29.86  ? 290 VAL B N   1 
ATOM   5053  C CA  . VAL B 2 315 ? 108.767 122.206 151.538 1.00 30.63  ? 290 VAL B CA  1 
ATOM   5054  C C   . VAL B 2 315 ? 108.962 121.438 152.840 1.00 32.72  ? 290 VAL B C   1 
ATOM   5055  O O   . VAL B 2 315 ? 108.517 121.877 153.907 1.00 39.04  ? 290 VAL B O   1 
ATOM   5056  C CB  . VAL B 2 315 ? 107.560 121.675 150.744 1.00 27.64  ? 290 VAL B CB  1 
ATOM   5057  C CG1 . VAL B 2 315 ? 106.349 121.531 151.647 1.00 21.63  ? 290 VAL B CG1 1 
ATOM   5058  C CG2 . VAL B 2 315 ? 107.242 122.602 149.588 1.00 29.97  ? 290 VAL B CG2 1 
ATOM   5059  N N   . PHE B 2 316 ? 109.640 120.290 152.778 1.00 27.51  ? 291 PHE B N   1 
ATOM   5060  C CA  . PHE B 2 316 ? 109.830 119.480 153.978 1.00 27.71  ? 291 PHE B CA  1 
ATOM   5061  C C   . PHE B 2 316 ? 110.691 120.202 155.006 1.00 28.94  ? 291 PHE B C   1 
ATOM   5062  O O   . PHE B 2 316 ? 110.388 120.176 156.204 1.00 32.51  ? 291 PHE B O   1 
ATOM   5063  C CB  . PHE B 2 316 ? 110.450 118.134 153.612 1.00 32.88  ? 291 PHE B CB  1 
ATOM   5064  C CG  . PHE B 2 316 ? 109.442 117.059 153.335 1.00 37.36  ? 291 PHE B CG  1 
ATOM   5065  C CD1 . PHE B 2 316 ? 108.916 116.301 154.365 1.00 38.24  ? 291 PHE B CD1 1 
ATOM   5066  C CD2 . PHE B 2 316 ? 109.026 116.802 152.040 1.00 33.54  ? 291 PHE B CD2 1 
ATOM   5067  C CE1 . PHE B 2 316 ? 107.988 115.312 154.107 1.00 36.11  ? 291 PHE B CE1 1 
ATOM   5068  C CE2 . PHE B 2 316 ? 108.101 115.816 151.779 1.00 33.51  ? 291 PHE B CE2 1 
ATOM   5069  C CZ  . PHE B 2 316 ? 107.581 115.070 152.813 1.00 37.07  ? 291 PHE B CZ  1 
ATOM   5070  N N   . VAL B 2 317 ? 111.774 120.843 154.564 1.00 27.50  ? 292 VAL B N   1 
ATOM   5071  C CA  . VAL B 2 317 ? 112.608 121.596 155.494 1.00 28.01  ? 292 VAL B CA  1 
ATOM   5072  C C   . VAL B 2 317 ? 111.888 122.859 155.954 1.00 31.92  ? 292 VAL B C   1 
ATOM   5073  O O   . VAL B 2 317 ? 112.045 123.295 157.100 1.00 39.32  ? 292 VAL B O   1 
ATOM   5074  C CB  . VAL B 2 317 ? 113.981 121.903 154.865 1.00 27.25  ? 292 VAL B CB  1 
ATOM   5075  C CG1 . VAL B 2 317 ? 114.675 120.614 154.466 1.00 30.88  ? 292 VAL B CG1 1 
ATOM   5076  C CG2 . VAL B 2 317 ? 113.845 122.811 153.660 1.00 26.82  ? 292 VAL B CG2 1 
ATOM   5077  N N   . PHE B 2 318 ? 111.100 123.476 155.067 1.00 30.82  ? 293 PHE B N   1 
ATOM   5078  C CA  . PHE B 2 318 ? 110.262 124.599 155.476 1.00 29.38  ? 293 PHE B CA  1 
ATOM   5079  C C   . PHE B 2 318 ? 109.269 124.186 156.555 1.00 31.54  ? 293 PHE B C   1 
ATOM   5080  O O   . PHE B 2 318 ? 109.053 124.922 157.524 1.00 36.17  ? 293 PHE B O   1 
ATOM   5081  C CB  . PHE B 2 318 ? 109.534 125.184 154.264 1.00 28.49  ? 293 PHE B CB  1 
ATOM   5082  C CG  . PHE B 2 318 ? 108.400 126.110 154.618 1.00 32.10  ? 293 PHE B CG  1 
ATOM   5083  C CD1 . PHE B 2 318 ? 108.623 127.463 154.793 1.00 30.97  ? 293 PHE B CD1 1 
ATOM   5084  C CD2 . PHE B 2 318 ? 107.104 125.632 154.738 1.00 32.52  ? 293 PHE B CD2 1 
ATOM   5085  C CE1 . PHE B 2 318 ? 107.582 128.315 155.110 1.00 28.83  ? 293 PHE B CE1 1 
ATOM   5086  C CE2 . PHE B 2 318 ? 106.062 126.480 155.054 1.00 27.84  ? 293 PHE B CE2 1 
ATOM   5087  C CZ  . PHE B 2 318 ? 106.301 127.822 155.239 1.00 25.67  ? 293 PHE B CZ  1 
ATOM   5088  N N   . LEU B 2 319 ? 108.650 123.014 156.400 1.00 29.24  ? 294 LEU B N   1 
ATOM   5089  C CA  . LEU B 2 319 ? 107.695 122.546 157.397 1.00 29.21  ? 294 LEU B CA  1 
ATOM   5090  C C   . LEU B 2 319 ? 108.380 122.131 158.692 1.00 34.52  ? 294 LEU B C   1 
ATOM   5091  O O   . LEU B 2 319 ? 107.802 122.297 159.772 1.00 38.05  ? 294 LEU B O   1 
ATOM   5092  C CB  . LEU B 2 319 ? 106.874 121.386 156.836 1.00 33.13  ? 294 LEU B CB  1 
ATOM   5093  C CG  . LEU B 2 319 ? 105.855 121.743 155.752 1.00 32.31  ? 294 LEU B CG  1 
ATOM   5094  C CD1 . LEU B 2 319 ? 105.185 120.494 155.207 1.00 32.52  ? 294 LEU B CD1 1 
ATOM   5095  C CD2 . LEU B 2 319 ? 104.821 122.713 156.292 1.00 36.01  ? 294 LEU B CD2 1 
ATOM   5096  N N   . ALA B 2 320 ? 109.597 121.588 158.612 1.00 34.23  ? 295 ALA B N   1 
ATOM   5097  C CA  . ALA B 2 320 ? 110.301 121.196 159.829 1.00 33.26  ? 295 ALA B CA  1 
ATOM   5098  C C   . ALA B 2 320 ? 110.623 122.403 160.699 1.00 39.39  ? 295 ALA B C   1 
ATOM   5099  O O   . ALA B 2 320 ? 110.481 122.345 161.925 1.00 50.60  ? 295 ALA B O   1 
ATOM   5100  C CB  . ALA B 2 320 ? 111.578 120.437 159.475 1.00 28.90  ? 295 ALA B CB  1 
ATOM   5101  N N   . LEU B 2 321 ? 111.071 123.501 160.088 1.00 35.58  ? 296 LEU B N   1 
ATOM   5102  C CA  . LEU B 2 321 ? 111.297 124.722 160.854 1.00 34.40  ? 296 LEU B CA  1 
ATOM   5103  C C   . LEU B 2 321 ? 109.984 125.293 161.375 1.00 37.38  ? 296 LEU B C   1 
ATOM   5104  O O   . LEU B 2 321 ? 109.909 125.747 162.523 1.00 38.11  ? 296 LEU B O   1 
ATOM   5105  C CB  . LEU B 2 321 ? 112.041 125.748 160.001 1.00 28.40  ? 296 LEU B CB  1 
ATOM   5106  C CG  . LEU B 2 321 ? 112.204 127.139 160.608 1.00 27.59  ? 296 LEU B CG  1 
ATOM   5107  C CD1 . LEU B 2 321 ? 112.932 127.053 161.936 1.00 29.34  ? 296 LEU B CD1 1 
ATOM   5108  C CD2 . LEU B 2 321 ? 112.964 128.027 159.651 1.00 23.95  ? 296 LEU B CD2 1 
ATOM   5109  N N   . LEU B 2 322 ? 108.940 125.278 160.543 1.00 37.47  ? 297 LEU B N   1 
ATOM   5110  C CA  . LEU B 2 322 ? 107.634 125.767 160.973 1.00 36.64  ? 297 LEU B CA  1 
ATOM   5111  C C   . LEU B 2 322 ? 107.032 124.872 162.046 1.00 40.66  ? 297 LEU B C   1 
ATOM   5112  O O   . LEU B 2 322 ? 106.154 125.308 162.799 1.00 47.20  ? 297 LEU B O   1 
ATOM   5113  C CB  . LEU B 2 322 ? 106.698 125.865 159.768 1.00 36.74  ? 297 LEU B CB  1 
ATOM   5114  C CG  . LEU B 2 322 ? 105.311 126.472 159.976 1.00 42.61  ? 297 LEU B CG  1 
ATOM   5115  C CD1 . LEU B 2 322 ? 105.421 127.923 160.405 1.00 43.84  ? 297 LEU B CD1 1 
ATOM   5116  C CD2 . LEU B 2 322 ? 104.483 126.345 158.710 1.00 42.75  ? 297 LEU B CD2 1 
ATOM   5117  N N   . GLU B 2 323 ? 107.485 123.620 162.128 1.00 37.81  ? 298 GLU B N   1 
ATOM   5118  C CA  . GLU B 2 323 ? 107.022 122.729 163.184 1.00 39.30  ? 298 GLU B CA  1 
ATOM   5119  C C   . GLU B 2 323 ? 107.452 123.229 164.556 1.00 44.40  ? 298 GLU B C   1 
ATOM   5120  O O   . GLU B 2 323 ? 106.683 123.153 165.522 1.00 43.14  ? 298 GLU B O   1 
ATOM   5121  C CB  . GLU B 2 323 ? 107.541 121.312 162.936 1.00 40.22  ? 298 GLU B CB  1 
ATOM   5122  C CG  . GLU B 2 323 ? 107.062 120.279 163.940 1.00 46.97  ? 298 GLU B CG  1 
ATOM   5123  C CD  . GLU B 2 323 ? 108.063 120.038 165.053 1.00 54.71  ? 298 GLU B CD  1 
ATOM   5124  O OE1 . GLU B 2 323 ? 109.075 120.764 165.115 1.00 52.89  ? 298 GLU B OE1 1 
ATOM   5125  O OE2 . GLU B 2 323 ? 107.840 119.118 165.867 1.00 61.07  ? 298 GLU B OE2 1 
ATOM   5126  N N   . TYR B 2 324 ? 108.683 123.734 164.668 1.00 46.71  ? 299 TYR B N   1 
ATOM   5127  C CA  . TYR B 2 324 ? 109.161 124.220 165.958 1.00 51.93  ? 299 TYR B CA  1 
ATOM   5128  C C   . TYR B 2 324 ? 108.425 125.483 166.390 1.00 56.71  ? 299 TYR B C   1 
ATOM   5129  O O   . TYR B 2 324 ? 108.185 125.687 167.586 1.00 60.15  ? 299 TYR B O   1 
ATOM   5130  C CB  . TYR B 2 324 ? 110.664 124.485 165.912 1.00 41.93  ? 299 TYR B CB  1 
ATOM   5131  C CG  . TYR B 2 324 ? 111.168 125.066 167.207 1.00 46.60  ? 299 TYR B CG  1 
ATOM   5132  C CD1 . TYR B 2 324 ? 111.154 124.309 168.368 1.00 54.96  ? 299 TYR B CD1 1 
ATOM   5133  C CD2 . TYR B 2 324 ? 111.613 126.376 167.284 1.00 45.92  ? 299 TYR B CD2 1 
ATOM   5134  C CE1 . TYR B 2 324 ? 111.593 124.825 169.560 1.00 57.31  ? 299 TYR B CE1 1 
ATOM   5135  C CE2 . TYR B 2 324 ? 112.055 126.905 168.478 1.00 51.18  ? 299 TYR B CE2 1 
ATOM   5136  C CZ  . TYR B 2 324 ? 112.041 126.121 169.613 1.00 56.67  ? 299 TYR B CZ  1 
ATOM   5137  O OH  . TYR B 2 324 ? 112.473 126.626 170.814 1.00 63.67  ? 299 TYR B OH  1 
ATOM   5138  N N   . ALA B 2 325 ? 108.076 126.350 165.437 1.00 51.82  ? 300 ALA B N   1 
ATOM   5139  C CA  . ALA B 2 325 ? 107.258 127.517 165.752 1.00 42.06  ? 300 ALA B CA  1 
ATOM   5140  C C   . ALA B 2 325 ? 105.968 127.112 166.449 1.00 48.99  ? 300 ALA B C   1 
ATOM   5141  O O   . ALA B 2 325 ? 105.527 127.768 167.400 1.00 51.90  ? 300 ALA B O   1 
ATOM   5142  C CB  . ALA B 2 325 ? 106.952 128.298 164.479 1.00 38.31  ? 300 ALA B CB  1 
ATOM   5143  N N   . PHE B 2 326 ? 105.339 126.036 165.978 1.00 51.95  ? 301 PHE B N   1 
ATOM   5144  C CA  . PHE B 2 326 ? 104.173 125.503 166.668 1.00 50.80  ? 301 PHE B CA  1 
ATOM   5145  C C   . PHE B 2 326 ? 104.557 124.958 168.038 1.00 53.94  ? 301 PHE B C   1 
ATOM   5146  O O   . PHE B 2 326 ? 103.782 125.059 168.995 1.00 59.73  ? 301 PHE B O   1 
ATOM   5147  C CB  . PHE B 2 326 ? 103.515 124.423 165.811 1.00 53.16  ? 301 PHE B CB  1 
ATOM   5148  C CG  . PHE B 2 326 ? 102.085 124.148 166.169 1.00 62.50  ? 301 PHE B CG  1 
ATOM   5149  C CD1 . PHE B 2 326 ? 101.088 125.044 165.826 1.00 68.44  ? 301 PHE B CD1 1 
ATOM   5150  C CD2 . PHE B 2 326 ? 101.733 122.985 166.833 1.00 69.09  ? 301 PHE B CD2 1 
ATOM   5151  C CE1 . PHE B 2 326 ? 99.768  124.792 166.150 1.00 76.45  ? 301 PHE B CE1 1 
ATOM   5152  C CE2 . PHE B 2 326 ? 100.415 122.727 167.158 1.00 74.77  ? 301 PHE B CE2 1 
ATOM   5153  C CZ  . PHE B 2 326 ? 99.432  123.631 166.816 1.00 78.86  ? 301 PHE B CZ  1 
ATOM   5154  N N   . VAL B 2 327 ? 105.754 124.376 168.148 1.00 47.33  ? 302 VAL B N   1 
ATOM   5155  C CA  . VAL B 2 327 ? 106.212 123.834 169.426 1.00 51.19  ? 302 VAL B CA  1 
ATOM   5156  C C   . VAL B 2 327 ? 106.527 124.959 170.405 1.00 56.14  ? 302 VAL B C   1 
ATOM   5157  O O   . VAL B 2 327 ? 106.158 124.904 171.584 1.00 61.10  ? 302 VAL B O   1 
ATOM   5158  C CB  . VAL B 2 327 ? 107.431 122.918 169.211 1.00 50.25  ? 302 VAL B CB  1 
ATOM   5159  C CG1 . VAL B 2 327 ? 108.087 122.580 170.540 1.00 59.19  ? 302 VAL B CG1 1 
ATOM   5160  C CG2 . VAL B 2 327 ? 107.022 121.658 168.476 1.00 55.57  ? 302 VAL B CG2 1 
ATOM   5161  N N   . ASN B 2 328 ? 107.244 125.983 169.940 1.00 56.79  ? 303 ASN B N   1 
ATOM   5162  C CA  . ASN B 2 328 ? 107.607 127.090 170.820 1.00 57.19  ? 303 ASN B CA  1 
ATOM   5163  C C   . ASN B 2 328 ? 106.372 127.834 171.316 1.00 61.21  ? 303 ASN B C   1 
ATOM   5164  O O   . ASN B 2 328 ? 106.286 128.190 172.497 1.00 62.57  ? 303 ASN B O   1 
ATOM   5165  C CB  . ASN B 2 328 ? 108.564 128.042 170.103 1.00 51.99  ? 303 ASN B CB  1 
ATOM   5166  C CG  . ASN B 2 328 ? 109.075 129.146 171.008 1.00 54.66  ? 303 ASN B CG  1 
ATOM   5167  O OD1 . ASN B 2 328 ? 108.339 130.062 171.371 1.00 59.77  ? 303 ASN B OD1 1 
ATOM   5168  N ND2 . ASN B 2 328 ? 110.345 129.060 171.382 1.00 56.38  ? 303 ASN B ND2 1 
ATOM   5169  N N   . TYR B 2 329 ? 105.410 128.089 170.426 1.00 61.07  ? 304 TYR B N   1 
ATOM   5170  C CA  . TYR B 2 329 ? 104.243 128.882 170.804 1.00 60.76  ? 304 TYR B CA  1 
ATOM   5171  C C   . TYR B 2 329 ? 103.372 128.159 171.823 1.00 68.25  ? 304 TYR B C   1 
ATOM   5172  O O   . TYR B 2 329 ? 102.857 128.785 172.753 1.00 79.13  ? 304 TYR B O   1 
ATOM   5173  C CB  . TYR B 2 329 ? 103.417 129.253 169.575 1.00 62.02  ? 304 TYR B CB  1 
ATOM   5174  C CG  . TYR B 2 329 ? 102.161 130.013 169.940 1.00 72.89  ? 304 TYR B CG  1 
ATOM   5175  C CD1 . TYR B 2 329 ? 102.210 131.367 170.238 1.00 75.13  ? 304 TYR B CD1 1 
ATOM   5176  C CD2 . TYR B 2 329 ? 100.930 129.374 169.998 1.00 77.80  ? 304 TYR B CD2 1 
ATOM   5177  C CE1 . TYR B 2 329 ? 101.069 132.065 170.580 1.00 79.65  ? 304 TYR B CE1 1 
ATOM   5178  C CE2 . TYR B 2 329 ? 99.784  130.063 170.339 1.00 81.72  ? 304 TYR B CE2 1 
ATOM   5179  C CZ  . TYR B 2 329 ? 99.859  131.408 170.628 1.00 86.34  ? 304 TYR B CZ  1 
ATOM   5180  O OH  . TYR B 2 329 ? 98.718  132.097 170.968 1.00 94.44  ? 304 TYR B OH  1 
ATOM   5181  N N   . ILE B 2 330 ? 103.173 126.851 171.659 1.00 61.93  ? 305 ILE B N   1 
ATOM   5182  C CA  . ILE B 2 330 ? 102.290 126.131 172.574 1.00 64.85  ? 305 ILE B CA  1 
ATOM   5183  C C   . ILE B 2 330 ? 102.862 126.143 173.988 1.00 71.53  ? 305 ILE B C   1 
ATOM   5184  O O   . ILE B 2 330 ? 102.130 126.340 174.965 1.00 78.73  ? 305 ILE B O   1 
ATOM   5185  C CB  . ILE B 2 330 ? 102.009 124.702 172.065 1.00 69.83  ? 305 ILE B CB  1 
ATOM   5186  C CG1 . ILE B 2 330 ? 100.996 124.004 172.975 1.00 79.66  ? 305 ILE B CG1 1 
ATOM   5187  C CG2 . ILE B 2 330 ? 103.274 123.874 171.967 1.00 70.59  ? 305 ILE B CG2 1 
ATOM   5188  C CD1 . ILE B 2 330 ? 100.428 122.728 172.392 1.00 80.73  ? 305 ILE B CD1 1 
ATOM   5189  N N   . PHE B 2 331 ? 104.174 125.937 174.124 1.00 66.27  ? 306 PHE B N   1 
ATOM   5190  C CA  . PHE B 2 331 ? 104.803 125.962 175.442 1.00 68.12  ? 306 PHE B CA  1 
ATOM   5191  C C   . PHE B 2 331 ? 104.851 127.372 176.028 1.00 68.78  ? 306 PHE B C   1 
ATOM   5192  O O   . PHE B 2 331 ? 104.272 127.633 177.089 1.00 69.86  ? 306 PHE B O   1 
ATOM   5193  C CB  . PHE B 2 331 ? 106.210 125.369 175.355 1.00 67.58  ? 306 PHE B CB  1 
ATOM   5194  C CG  . PHE B 2 331 ? 106.903 125.257 176.682 1.00 73.09  ? 306 PHE B CG  1 
ATOM   5195  C CD1 . PHE B 2 331 ? 106.711 124.149 177.488 1.00 76.45  ? 306 PHE B CD1 1 
ATOM   5196  C CD2 . PHE B 2 331 ? 107.753 126.260 177.120 1.00 69.02  ? 306 PHE B CD2 1 
ATOM   5197  C CE1 . PHE B 2 331 ? 107.347 124.046 178.710 1.00 76.44  ? 306 PHE B CE1 1 
ATOM   5198  C CE2 . PHE B 2 331 ? 108.393 126.162 178.340 1.00 71.08  ? 306 PHE B CE2 1 
ATOM   5199  C CZ  . PHE B 2 331 ? 108.191 125.054 179.135 1.00 76.84  ? 306 PHE B CZ  1 
ATOM   5200  N N   . PHE B 2 332 ? 105.540 128.300 175.357 1.00 69.76  ? 307 PHE B N   1 
ATOM   5201  C CA  . PHE B 2 332 ? 105.719 129.628 175.940 1.00 73.57  ? 307 PHE B CA  1 
ATOM   5202  C C   . PHE B 2 332 ? 104.464 130.488 175.829 1.00 74.10  ? 307 PHE B C   1 
ATOM   5203  O O   . PHE B 2 332 ? 104.157 131.259 176.746 1.00 71.59  ? 307 PHE B O   1 
ATOM   5204  C CB  . PHE B 2 332 ? 106.900 130.340 175.280 1.00 77.53  ? 307 PHE B CB  1 
ATOM   5205  C CG  . PHE B 2 332 ? 108.233 129.720 175.589 1.00 80.40  ? 307 PHE B CG  1 
ATOM   5206  C CD1 . PHE B 2 332 ? 108.801 129.861 176.843 1.00 80.52  ? 307 PHE B CD1 1 
ATOM   5207  C CD2 . PHE B 2 332 ? 108.923 129.008 174.623 1.00 81.05  ? 307 PHE B CD2 1 
ATOM   5208  C CE1 . PHE B 2 332 ? 110.027 129.296 177.131 1.00 84.50  ? 307 PHE B CE1 1 
ATOM   5209  C CE2 . PHE B 2 332 ? 110.150 128.440 174.905 1.00 81.42  ? 307 PHE B CE2 1 
ATOM   5210  C CZ  . PHE B 2 332 ? 110.702 128.585 176.160 1.00 81.40  ? 307 PHE B CZ  1 
ATOM   5211  N N   . GLY B 2 333 ? 103.733 130.378 174.727 1.00 77.42  ? 308 GLY B N   1 
ATOM   5212  C CA  . GLY B 2 333 ? 102.560 131.205 174.518 1.00 75.08  ? 308 GLY B CA  1 
ATOM   5213  C C   . GLY B 2 333 ? 101.361 130.717 175.303 1.00 79.54  ? 308 GLY B C   1 
ATOM   5214  O O   . GLY B 2 333 ? 100.839 131.424 176.170 1.00 86.72  ? 308 GLY B O   1 
ATOM   5215  N N   . ARG B 2 334 ? 100.919 129.501 175.001 1.00 78.14  ? 309 ARG B N   1 
ATOM   5216  C CA  . ARG B 2 334 ? 99.721  128.934 175.602 1.00 79.37  ? 309 ARG B CA  1 
ATOM   5217  C C   . ARG B 2 334 ? 100.073 128.071 176.807 1.00 76.83  ? 309 ARG B C   1 
ATOM   5218  O O   . ARG B 2 334 ? 101.202 128.102 177.296 1.00 77.04  ? 309 ARG B O   1 
ATOM   5219  C CB  . ARG B 2 334 ? 98.961  128.101 174.568 1.00 78.25  ? 309 ARG B CB  1 
ATOM   5220  C CG  . ARG B 2 334 ? 98.327  128.916 173.456 1.00 86.22  ? 309 ARG B CG  1 
ATOM   5221  C CD  . ARG B 2 334 ? 97.295  128.103 172.692 1.00 96.90  ? 309 ARG B CD  1 
ATOM   5222  N NE  . ARG B 2 334 ? 96.443  128.945 171.861 1.00 101.88 ? 309 ARG B NE  1 
ATOM   5223  C CZ  . ARG B 2 334 ? 95.353  128.523 171.234 1.00 101.02 ? 309 ARG B CZ  1 
ATOM   5224  N NH1 . ARG B 2 334 ? 94.947  127.267 171.324 1.00 91.77  ? 309 ARG B NH1 1 
ATOM   5225  N NH2 . ARG B 2 334 ? 94.654  129.383 170.500 1.00 102.49 ? 309 ARG B NH2 1 
ATOM   5226  N N   . ASP B 2 444 ? 101.582 117.184 175.980 1.00 76.02  ? 444 ASP B N   1 
ATOM   5227  C CA  . ASP B 2 444 ? 101.313 118.162 174.932 1.00 82.38  ? 444 ASP B CA  1 
ATOM   5228  C C   . ASP B 2 444 ? 102.582 118.523 174.168 1.00 82.67  ? 444 ASP B C   1 
ATOM   5229  O O   . ASP B 2 444 ? 102.666 118.313 172.958 1.00 86.21  ? 444 ASP B O   1 
ATOM   5230  C CB  . ASP B 2 444 ? 100.684 119.425 175.523 1.00 85.22  ? 444 ASP B CB  1 
ATOM   5231  C CG  . ASP B 2 444 ? 99.178  119.453 175.367 1.00 85.47  ? 444 ASP B CG  1 
ATOM   5232  O OD1 . ASP B 2 444 ? 98.584  118.381 175.125 1.00 83.27  ? 444 ASP B OD1 1 
ATOM   5233  O OD2 . ASP B 2 444 ? 98.587  120.547 175.483 1.00 83.98  ? 444 ASP B OD2 1 
ATOM   5234  N N   . VAL B 2 445 ? 103.562 119.078 174.885 1.00 83.49  ? 445 VAL B N   1 
ATOM   5235  C CA  . VAL B 2 445 ? 104.789 119.543 174.243 1.00 90.50  ? 445 VAL B CA  1 
ATOM   5236  C C   . VAL B 2 445 ? 105.531 118.382 173.595 1.00 85.27  ? 445 VAL B C   1 
ATOM   5237  O O   . VAL B 2 445 ? 106.003 118.485 172.456 1.00 77.58  ? 445 VAL B O   1 
ATOM   5238  C CB  . VAL B 2 445 ? 105.677 120.281 175.261 1.00 82.71  ? 445 VAL B CB  1 
ATOM   5239  C CG1 . VAL B 2 445 ? 106.832 120.972 174.556 1.00 76.86  ? 445 VAL B CG1 1 
ATOM   5240  C CG2 . VAL B 2 445 ? 104.853 121.284 176.053 1.00 76.53  ? 445 VAL B CG2 1 
ATOM   5241  N N   . ASN B 2 446 ? 105.646 117.260 174.307 1.00 79.20  ? 446 ASN B N   1 
ATOM   5242  C CA  . ASN B 2 446 ? 106.397 116.128 173.775 1.00 77.63  ? 446 ASN B CA  1 
ATOM   5243  C C   . ASN B 2 446 ? 105.625 115.422 172.668 1.00 80.28  ? 446 ASN B C   1 
ATOM   5244  O O   . ASN B 2 446 ? 106.225 114.770 171.804 1.00 77.76  ? 446 ASN B O   1 
ATOM   5245  C CB  . ASN B 2 446 ? 106.739 115.152 174.900 1.00 79.94  ? 446 ASN B CB  1 
ATOM   5246  C CG  . ASN B 2 446 ? 107.780 114.132 174.488 1.00 83.38  ? 446 ASN B CG  1 
ATOM   5247  O OD1 . ASN B 2 446 ? 108.584 114.379 173.589 1.00 77.93  ? 446 ASN B OD1 1 
ATOM   5248  N ND2 . ASN B 2 446 ? 107.771 112.978 175.143 1.00 84.49  ? 446 ASN B ND2 1 
ATOM   5249  N N   . ALA B 2 447 ? 104.294 115.537 172.675 1.00 84.01  ? 447 ALA B N   1 
ATOM   5250  C CA  . ALA B 2 447 ? 103.493 114.855 171.663 1.00 77.93  ? 447 ALA B CA  1 
ATOM   5251  C C   . ALA B 2 447 ? 103.797 115.383 170.267 1.00 68.74  ? 447 ALA B C   1 
ATOM   5252  O O   . ALA B 2 447 ? 103.906 114.605 169.312 1.00 69.06  ? 447 ALA B O   1 
ATOM   5253  C CB  . ALA B 2 447 ? 102.006 115.006 171.982 1.00 76.62  ? 447 ALA B CB  1 
ATOM   5254  N N   . ILE B 2 448 ? 103.921 116.704 170.125 1.00 66.68  ? 448 ILE B N   1 
ATOM   5255  C CA  . ILE B 2 448 ? 104.171 117.292 168.812 1.00 69.08  ? 448 ILE B CA  1 
ATOM   5256  C C   . ILE B 2 448 ? 105.516 116.826 168.267 1.00 69.87  ? 448 ILE B C   1 
ATOM   5257  O O   . ILE B 2 448 ? 105.644 116.495 167.082 1.00 67.34  ? 448 ILE B O   1 
ATOM   5258  C CB  . ILE B 2 448 ? 104.091 118.827 168.882 1.00 66.63  ? 448 ILE B CB  1 
ATOM   5259  C CG1 . ILE B 2 448 ? 102.727 119.270 169.407 1.00 69.61  ? 448 ILE B CG1 1 
ATOM   5260  C CG2 . ILE B 2 448 ? 104.322 119.428 167.509 1.00 56.60  ? 448 ILE B CG2 1 
ATOM   5261  C CD1 . ILE B 2 448 ? 102.655 120.745 169.738 1.00 65.11  ? 448 ILE B CD1 1 
ATOM   5262  N N   . ASP B 2 449 ? 106.540 116.794 169.125 1.00 70.44  ? 449 ASP B N   1 
ATOM   5263  C CA  . ASP B 2 449 ? 107.858 116.333 168.701 1.00 66.16  ? 449 ASP B CA  1 
ATOM   5264  C C   . ASP B 2 449 ? 107.874 114.831 168.445 1.00 64.59  ? 449 ASP B C   1 
ATOM   5265  O O   . ASP B 2 449 ? 108.411 114.376 167.428 1.00 63.27  ? 449 ASP B O   1 
ATOM   5266  C CB  . ASP B 2 449 ? 108.910 116.707 169.746 1.00 67.45  ? 449 ASP B CB  1 
ATOM   5267  C CG  . ASP B 2 449 ? 109.373 118.143 169.618 1.00 67.27  ? 449 ASP B CG  1 
ATOM   5268  O OD1 . ASP B 2 449 ? 109.333 118.683 168.493 1.00 62.06  ? 449 ASP B OD1 1 
ATOM   5269  O OD2 . ASP B 2 449 ? 109.784 118.730 170.641 1.00 74.25  ? 449 ASP B OD2 1 
ATOM   5270  N N   . ARG B 2 450 ? 107.301 114.042 169.358 1.00 66.24  ? 450 ARG B N   1 
ATOM   5271  C CA  . ARG B 2 450 ? 107.270 112.595 169.160 1.00 67.60  ? 450 ARG B CA  1 
ATOM   5272  C C   . ARG B 2 450 ? 106.556 112.227 167.865 1.00 65.34  ? 450 ARG B C   1 
ATOM   5273  O O   . ARG B 2 450 ? 107.029 111.376 167.103 1.00 62.77  ? 450 ARG B O   1 
ATOM   5274  C CB  . ARG B 2 450 ? 106.602 111.902 170.346 1.00 73.62  ? 450 ARG B CB  1 
ATOM   5275  C CG  . ARG B 2 450 ? 106.837 110.402 170.344 1.00 82.62  ? 450 ARG B CG  1 
ATOM   5276  C CD  . ARG B 2 450 ? 106.131 109.691 171.482 1.00 95.36  ? 450 ARG B CD  1 
ATOM   5277  N NE  . ARG B 2 450 ? 106.312 108.248 171.381 1.00 108.82 ? 450 ARG B NE  1 
ATOM   5278  C CZ  . ARG B 2 450 ? 105.742 107.360 172.183 1.00 106.70 ? 450 ARG B CZ  1 
ATOM   5279  N NH1 . ARG B 2 450 ? 104.940 107.731 173.168 1.00 99.82  ? 450 ARG B NH1 1 
ATOM   5280  N NH2 . ARG B 2 450 ? 105.980 106.065 171.991 1.00 105.81 ? 450 ARG B NH2 1 
ATOM   5281  N N   . TRP B 2 451 ? 105.409 112.854 167.601 1.00 66.67  ? 451 TRP B N   1 
ATOM   5282  C CA  . TRP B 2 451 ? 104.700 112.577 166.357 1.00 63.13  ? 451 TRP B CA  1 
ATOM   5283  C C   . TRP B 2 451 ? 105.504 113.039 165.151 1.00 55.60  ? 451 TRP B C   1 
ATOM   5284  O O   . TRP B 2 451 ? 105.473 112.398 164.094 1.00 51.82  ? 451 TRP B O   1 
ATOM   5285  C CB  . TRP B 2 451 ? 103.322 113.237 166.371 1.00 65.33  ? 451 TRP B CB  1 
ATOM   5286  C CG  . TRP B 2 451 ? 102.262 112.381 166.988 1.00 74.93  ? 451 TRP B CG  1 
ATOM   5287  C CD1 . TRP B 2 451 ? 101.748 112.491 168.246 1.00 78.32  ? 451 TRP B CD1 1 
ATOM   5288  C CD2 . TRP B 2 451 ? 101.587 111.277 166.374 1.00 79.29  ? 451 TRP B CD2 1 
ATOM   5289  N NE1 . TRP B 2 451 ? 100.793 111.526 168.454 1.00 77.57  ? 451 TRP B NE1 1 
ATOM   5290  C CE2 . TRP B 2 451 ? 100.676 110.767 167.320 1.00 81.81  ? 451 TRP B CE2 1 
ATOM   5291  C CE3 . TRP B 2 451 ? 101.665 110.670 165.117 1.00 76.19  ? 451 TRP B CE3 1 
ATOM   5292  C CZ2 . TRP B 2 451 ? 99.848  109.680 167.048 1.00 78.40  ? 451 TRP B CZ2 1 
ATOM   5293  C CZ3 . TRP B 2 451 ? 100.842 109.592 164.849 1.00 78.69  ? 451 TRP B CZ3 1 
ATOM   5294  C CH2 . TRP B 2 451 ? 99.945  109.108 165.809 1.00 78.77  ? 451 TRP B CH2 1 
ATOM   5295  N N   . SER B 2 452 ? 106.234 114.148 165.285 1.00 57.05  ? 452 SER B N   1 
ATOM   5296  C CA  . SER B 2 452 ? 107.015 114.631 164.155 1.00 52.24  ? 452 SER B CA  1 
ATOM   5297  C C   . SER B 2 452 ? 108.202 113.727 163.857 1.00 53.98  ? 452 SER B C   1 
ATOM   5298  O O   . SER B 2 452 ? 108.644 113.658 162.705 1.00 53.10  ? 452 SER B O   1 
ATOM   5299  C CB  . SER B 2 452 ? 107.496 116.057 164.422 1.00 46.24  ? 452 SER B CB  1 
ATOM   5300  O OG  . SER B 2 452 ? 106.442 116.988 164.253 1.00 45.93  ? 452 SER B OG  1 
ATOM   5301  N N   . ARG B 2 453 ? 108.731 113.032 164.867 1.00 54.87  ? 453 ARG B N   1 
ATOM   5302  C CA  . ARG B 2 453 ? 109.861 112.141 164.636 1.00 47.49  ? 453 ARG B CA  1 
ATOM   5303  C C   . ARG B 2 453 ? 109.486 110.938 163.782 1.00 47.88  ? 453 ARG B C   1 
ATOM   5304  O O   . ARG B 2 453 ? 110.381 110.223 163.320 1.00 49.23  ? 453 ARG B O   1 
ATOM   5305  C CB  . ARG B 2 453 ? 110.449 111.666 165.965 1.00 49.49  ? 453 ARG B CB  1 
ATOM   5306  C CG  . ARG B 2 453 ? 111.115 112.760 166.780 1.00 50.26  ? 453 ARG B CG  1 
ATOM   5307  C CD  . ARG B 2 453 ? 111.385 112.292 168.199 1.00 51.25  ? 453 ARG B CD  1 
ATOM   5308  N NE  . ARG B 2 453 ? 111.858 113.372 169.056 1.00 55.01  ? 453 ARG B NE  1 
ATOM   5309  C CZ  . ARG B 2 453 ? 112.168 113.229 170.337 1.00 57.47  ? 453 ARG B CZ  1 
ATOM   5310  N NH1 . ARG B 2 453 ? 112.063 112.060 170.946 1.00 59.88  ? 453 ARG B NH1 1 
ATOM   5311  N NH2 . ARG B 2 453 ? 112.592 114.286 171.024 1.00 56.13  ? 453 ARG B NH2 1 
ATOM   5312  N N   . ILE B 2 454 ? 108.195 110.703 163.563 1.00 50.41  ? 454 ILE B N   1 
ATOM   5313  C CA  . ILE B 2 454 ? 107.709 109.587 162.765 1.00 49.58  ? 454 ILE B CA  1 
ATOM   5314  C C   . ILE B 2 454 ? 107.055 110.068 161.477 1.00 48.69  ? 454 ILE B C   1 
ATOM   5315  O O   . ILE B 2 454 ? 107.336 109.547 160.398 1.00 45.40  ? 454 ILE B O   1 
ATOM   5316  C CB  . ILE B 2 454 ? 106.738 108.704 163.580 1.00 47.70  ? 454 ILE B CB  1 
ATOM   5317  C CG1 . ILE B 2 454 ? 107.425 108.169 164.837 1.00 51.45  ? 454 ILE B CG1 1 
ATOM   5318  C CG2 . ILE B 2 454 ? 106.205 107.567 162.725 1.00 42.13  ? 454 ILE B CG2 1 
ATOM   5319  C CD1 . ILE B 2 454 ? 106.481 107.499 165.807 1.00 52.59  ? 454 ILE B CD1 1 
ATOM   5320  N N   . VAL B 2 455 ? 106.177 111.070 161.573 1.00 50.38  ? 455 VAL B N   1 
ATOM   5321  C CA  . VAL B 2 455 ? 105.401 111.495 160.412 1.00 45.64  ? 455 VAL B CA  1 
ATOM   5322  C C   . VAL B 2 455 ? 106.316 112.058 159.333 1.00 42.35  ? 455 VAL B C   1 
ATOM   5323  O O   . VAL B 2 455 ? 106.177 111.731 158.149 1.00 42.95  ? 455 VAL B O   1 
ATOM   5324  C CB  . VAL B 2 455 ? 104.326 112.515 160.827 1.00 44.13  ? 455 VAL B CB  1 
ATOM   5325  C CG1 . VAL B 2 455 ? 103.630 113.074 159.601 1.00 46.45  ? 455 VAL B CG1 1 
ATOM   5326  C CG2 . VAL B 2 455 ? 103.315 111.870 161.759 1.00 46.00  ? 455 VAL B CG2 1 
ATOM   5327  N N   . PHE B 2 456 ? 107.266 112.910 159.722 1.00 39.39  ? 456 PHE B N   1 
ATOM   5328  C CA  . PHE B 2 456 ? 108.156 113.507 158.728 1.00 38.43  ? 456 PHE B CA  1 
ATOM   5329  C C   . PHE B 2 456 ? 109.003 112.457 158.020 1.00 40.51  ? 456 PHE B C   1 
ATOM   5330  O O   . PHE B 2 456 ? 109.043 112.471 156.778 1.00 40.76  ? 456 PHE B O   1 
ATOM   5331  C CB  . PHE B 2 456 ? 108.998 114.609 159.379 1.00 36.51  ? 456 PHE B CB  1 
ATOM   5332  C CG  . PHE B 2 456 ? 108.322 115.948 159.398 1.00 42.16  ? 456 PHE B CG  1 
ATOM   5333  C CD1 . PHE B 2 456 ? 107.441 116.278 160.412 1.00 46.25  ? 456 PHE B CD1 1 
ATOM   5334  C CD2 . PHE B 2 456 ? 108.558 116.873 158.397 1.00 36.17  ? 456 PHE B CD2 1 
ATOM   5335  C CE1 . PHE B 2 456 ? 106.813 117.508 160.430 1.00 45.75  ? 456 PHE B CE1 1 
ATOM   5336  C CE2 . PHE B 2 456 ? 107.934 118.103 158.411 1.00 35.87  ? 456 PHE B CE2 1 
ATOM   5337  C CZ  . PHE B 2 456 ? 107.061 118.420 159.428 1.00 37.32  ? 456 PHE B CZ  1 
ATOM   5338  N N   . PRO B 2 457 ? 109.713 111.552 158.711 1.00 39.57  ? 457 PRO B N   1 
ATOM   5339  C CA  . PRO B 2 457 ? 110.394 110.476 157.972 1.00 36.48  ? 457 PRO B CA  1 
ATOM   5340  C C   . PRO B 2 457 ? 109.431 109.629 157.161 1.00 41.01  ? 457 PRO B C   1 
ATOM   5341  O O   . PRO B 2 457 ? 109.768 109.196 156.052 1.00 42.62  ? 457 PRO B O   1 
ATOM   5342  C CB  . PRO B 2 457 ? 111.075 109.663 159.081 1.00 37.29  ? 457 PRO B CB  1 
ATOM   5343  C CG  . PRO B 2 457 ? 111.254 110.616 160.192 1.00 40.09  ? 457 PRO B CG  1 
ATOM   5344  C CD  . PRO B 2 457 ? 110.076 111.539 160.141 1.00 39.99  ? 457 PRO B CD  1 
ATOM   5345  N N   . PHE B 2 458 ? 108.231 109.382 157.691 1.00 43.77  ? 458 PHE B N   1 
ATOM   5346  C CA  . PHE B 2 458 ? 107.262 108.540 156.997 1.00 45.34  ? 458 PHE B CA  1 
ATOM   5347  C C   . PHE B 2 458 ? 106.717 109.248 155.764 1.00 45.53  ? 458 PHE B C   1 
ATOM   5348  O O   . PHE B 2 458 ? 106.637 108.656 154.681 1.00 43.47  ? 458 PHE B O   1 
ATOM   5349  C CB  . PHE B 2 458 ? 106.131 108.151 157.951 1.00 43.90  ? 458 PHE B CB  1 
ATOM   5350  C CG  . PHE B 2 458 ? 104.990 107.437 157.291 1.00 51.73  ? 458 PHE B CG  1 
ATOM   5351  C CD1 . PHE B 2 458 ? 105.098 106.101 156.950 1.00 55.08  ? 458 PHE B CD1 1 
ATOM   5352  C CD2 . PHE B 2 458 ? 103.802 108.097 157.025 1.00 55.23  ? 458 PHE B CD2 1 
ATOM   5353  C CE1 . PHE B 2 458 ? 104.046 105.439 156.348 1.00 60.06  ? 458 PHE B CE1 1 
ATOM   5354  C CE2 . PHE B 2 458 ? 102.748 107.441 156.423 1.00 56.24  ? 458 PHE B CE2 1 
ATOM   5355  C CZ  . PHE B 2 458 ? 102.870 106.111 156.084 1.00 58.85  ? 458 PHE B CZ  1 
ATOM   5356  N N   . THR B 2 459 ? 106.332 110.519 155.908 1.00 46.52  ? 459 THR B N   1 
ATOM   5357  C CA  . THR B 2 459 ? 105.738 111.232 154.783 1.00 43.47  ? 459 THR B CA  1 
ATOM   5358  C C   . THR B 2 459 ? 106.766 111.478 153.688 1.00 44.77  ? 459 THR B C   1 
ATOM   5359  O O   . THR B 2 459 ? 106.419 111.477 152.501 1.00 46.16  ? 459 THR B O   1 
ATOM   5360  C CB  . THR B 2 459 ? 105.133 112.555 155.253 1.00 41.92  ? 459 THR B CB  1 
ATOM   5361  O OG1 . THR B 2 459 ? 104.220 112.309 156.328 1.00 40.89  ? 459 THR B OG1 1 
ATOM   5362  C CG2 . THR B 2 459 ? 104.385 113.236 154.121 1.00 42.95  ? 459 THR B CG2 1 
ATOM   5363  N N   . PHE B 2 460 ? 108.033 111.681 154.061 1.00 40.57  ? 460 PHE B N   1 
ATOM   5364  C CA  . PHE B 2 460 ? 109.078 111.813 153.054 1.00 36.32  ? 460 PHE B CA  1 
ATOM   5365  C C   . PHE B 2 460 ? 109.261 110.508 152.295 1.00 39.62  ? 460 PHE B C   1 
ATOM   5366  O O   . PHE B 2 460 ? 109.475 110.516 151.077 1.00 41.64  ? 460 PHE B O   1 
ATOM   5367  C CB  . PHE B 2 460 ? 110.389 112.252 153.699 1.00 34.41  ? 460 PHE B CB  1 
ATOM   5368  C CG  . PHE B 2 460 ? 111.445 112.654 152.709 1.00 32.97  ? 460 PHE B CG  1 
ATOM   5369  C CD1 . PHE B 2 460 ? 111.222 113.692 151.822 1.00 37.29  ? 460 PHE B CD1 1 
ATOM   5370  C CD2 . PHE B 2 460 ? 112.666 112.003 152.674 1.00 28.21  ? 460 PHE B CD2 1 
ATOM   5371  C CE1 . PHE B 2 460 ? 112.190 114.065 150.914 1.00 35.40  ? 460 PHE B CE1 1 
ATOM   5372  C CE2 . PHE B 2 460 ? 113.639 112.375 151.770 1.00 31.39  ? 460 PHE B CE2 1 
ATOM   5373  C CZ  . PHE B 2 460 ? 113.399 113.406 150.888 1.00 34.66  ? 460 PHE B CZ  1 
ATOM   5374  N N   . SER B 2 461 ? 109.191 109.376 153.002 1.00 37.65  ? 461 SER B N   1 
ATOM   5375  C CA  . SER B 2 461 ? 109.210 108.086 152.323 1.00 41.38  ? 461 SER B CA  1 
ATOM   5376  C C   . SER B 2 461 ? 108.016 107.955 151.389 1.00 42.63  ? 461 SER B C   1 
ATOM   5377  O O   . SER B 2 461 ? 108.153 107.479 150.256 1.00 40.31  ? 461 SER B O   1 
ATOM   5378  C CB  . SER B 2 461 ? 109.225 106.951 153.346 1.00 39.46  ? 461 SER B CB  1 
ATOM   5379  O OG  . SER B 2 461 ? 110.353 107.049 154.195 1.00 36.57  ? 461 SER B OG  1 
ATOM   5380  N N   . LEU B 2 462 ? 106.832 108.368 151.850 1.00 42.34  ? 462 LEU B N   1 
ATOM   5381  C CA  . LEU B 2 462 ? 105.651 108.318 150.997 1.00 42.43  ? 462 LEU B CA  1 
ATOM   5382  C C   . LEU B 2 462 ? 105.816 109.233 149.792 1.00 42.60  ? 462 LEU B C   1 
ATOM   5383  O O   . LEU B 2 462 ? 105.437 108.873 148.672 1.00 46.12  ? 462 LEU B O   1 
ATOM   5384  C CB  . LEU B 2 462 ? 104.406 108.700 151.796 1.00 43.99  ? 462 LEU B CB  1 
ATOM   5385  C CG  . LEU B 2 462 ? 103.073 108.595 151.054 1.00 42.69  ? 462 LEU B CG  1 
ATOM   5386  C CD1 . LEU B 2 462 ? 102.830 107.169 150.591 1.00 40.19  ? 462 LEU B CD1 1 
ATOM   5387  C CD2 . LEU B 2 462 ? 101.930 109.083 151.929 1.00 44.94  ? 462 LEU B CD2 1 
ATOM   5388  N N   . PHE B 2 463 ? 106.365 110.432 150.008 1.00 38.71  ? 463 PHE B N   1 
ATOM   5389  C CA  . PHE B 2 463 ? 106.632 111.329 148.889 1.00 35.39  ? 463 PHE B CA  1 
ATOM   5390  C C   . PHE B 2 463 ? 107.618 110.694 147.920 1.00 39.90  ? 463 PHE B C   1 
ATOM   5391  O O   . PHE B 2 463 ? 107.443 110.777 146.698 1.00 39.48  ? 463 PHE B O   1 
ATOM   5392  C CB  . PHE B 2 463 ? 107.151 112.674 149.397 1.00 32.69  ? 463 PHE B CB  1 
ATOM   5393  C CG  . PHE B 2 463 ? 107.891 113.471 148.359 1.00 32.90  ? 463 PHE B CG  1 
ATOM   5394  C CD1 . PHE B 2 463 ? 107.201 114.251 147.447 1.00 29.71  ? 463 PHE B CD1 1 
ATOM   5395  C CD2 . PHE B 2 463 ? 109.275 113.460 148.308 1.00 33.20  ? 463 PHE B CD2 1 
ATOM   5396  C CE1 . PHE B 2 463 ? 107.874 114.988 146.494 1.00 23.10  ? 463 PHE B CE1 1 
ATOM   5397  C CE2 . PHE B 2 463 ? 109.952 114.196 147.358 1.00 29.60  ? 463 PHE B CE2 1 
ATOM   5398  C CZ  . PHE B 2 463 ? 109.250 114.961 146.450 1.00 26.32  ? 463 PHE B CZ  1 
ATOM   5399  N N   . ASN B 2 464 ? 108.671 110.064 148.449 1.00 41.34  ? 464 ASN B N   1 
ATOM   5400  C CA  . ASN B 2 464 ? 109.655 109.420 147.588 1.00 41.45  ? 464 ASN B CA  1 
ATOM   5401  C C   . ASN B 2 464 ? 109.034 108.259 146.828 1.00 47.33  ? 464 ASN B C   1 
ATOM   5402  O O   . ASN B 2 464 ? 109.282 108.089 145.629 1.00 46.87  ? 464 ASN B O   1 
ATOM   5403  C CB  . ASN B 2 464 ? 110.845 108.938 148.415 1.00 38.54  ? 464 ASN B CB  1 
ATOM   5404  C CG  . ASN B 2 464 ? 111.869 110.023 148.644 1.00 41.00  ? 464 ASN B CG  1 
ATOM   5405  O OD1 . ASN B 2 464 ? 112.571 110.434 147.722 1.00 41.94  ? 464 ASN B OD1 1 
ATOM   5406  N ND2 . ASN B 2 464 ? 111.957 110.498 149.876 1.00 44.22  ? 464 ASN B ND2 1 
ATOM   5407  N N   . LEU B 2 465 ? 108.219 107.449 147.510 1.00 46.69  ? 465 LEU B N   1 
ATOM   5408  C CA  . LEU B 2 465 ? 107.563 106.330 146.843 1.00 42.90  ? 465 LEU B CA  1 
ATOM   5409  C C   . LEU B 2 465 ? 106.725 106.822 145.671 1.00 44.93  ? 465 LEU B C   1 
ATOM   5410  O O   . LEU B 2 465 ? 106.801 106.277 144.565 1.00 50.29  ? 465 LEU B O   1 
ATOM   5411  C CB  . LEU B 2 465 ? 106.704 105.557 147.842 1.00 46.66  ? 465 LEU B CB  1 
ATOM   5412  C CG  . LEU B 2 465 ? 106.147 104.217 147.367 1.00 52.54  ? 465 LEU B CG  1 
ATOM   5413  C CD1 . LEU B 2 465 ? 107.256 103.181 147.311 1.00 50.94  ? 465 LEU B CD1 1 
ATOM   5414  C CD2 . LEU B 2 465 ? 105.020 103.753 148.274 1.00 54.59  ? 465 LEU B CD2 1 
ATOM   5415  N N   . VAL B 2 466 ? 105.912 107.855 145.902 1.00 42.90  ? 466 VAL B N   1 
ATOM   5416  C CA  . VAL B 2 466 ? 105.079 108.403 144.836 1.00 44.02  ? 466 VAL B CA  1 
ATOM   5417  C C   . VAL B 2 466 ? 105.950 108.974 143.724 1.00 46.57  ? 466 VAL B C   1 
ATOM   5418  O O   . VAL B 2 466 ? 105.689 108.755 142.535 1.00 47.54  ? 466 VAL B O   1 
ATOM   5419  C CB  . VAL B 2 466 ? 104.117 109.463 145.404 1.00 44.39  ? 466 VAL B CB  1 
ATOM   5420  C CG1 . VAL B 2 466 ? 103.419 110.208 144.282 1.00 46.68  ? 466 VAL B CG1 1 
ATOM   5421  C CG2 . VAL B 2 466 ? 103.101 108.814 146.327 1.00 44.00  ? 466 VAL B CG2 1 
ATOM   5422  N N   . TYR B 2 467 ? 106.995 109.720 144.095 1.00 41.73  ? 467 TYR B N   1 
ATOM   5423  C CA  . TYR B 2 467 ? 107.859 110.354 143.104 1.00 40.70  ? 467 TYR B CA  1 
ATOM   5424  C C   . TYR B 2 467 ? 108.525 109.323 142.201 1.00 46.00  ? 467 TYR B C   1 
ATOM   5425  O O   . TYR B 2 467 ? 108.478 109.436 140.970 1.00 48.92  ? 467 TYR B O   1 
ATOM   5426  C CB  . TYR B 2 467 ? 108.911 111.214 143.805 1.00 35.38  ? 467 TYR B CB  1 
ATOM   5427  C CG  . TYR B 2 467 ? 109.897 111.872 142.867 1.00 34.75  ? 467 TYR B CG  1 
ATOM   5428  C CD1 . TYR B 2 467 ? 109.605 113.087 142.267 1.00 35.25  ? 467 TYR B CD1 1 
ATOM   5429  C CD2 . TYR B 2 467 ? 111.122 111.284 142.591 1.00 37.25  ? 467 TYR B CD2 1 
ATOM   5430  C CE1 . TYR B 2 467 ? 110.503 113.695 141.415 1.00 34.86  ? 467 TYR B CE1 1 
ATOM   5431  C CE2 . TYR B 2 467 ? 112.025 111.883 141.738 1.00 37.80  ? 467 TYR B CE2 1 
ATOM   5432  C CZ  . TYR B 2 467 ? 111.710 113.088 141.153 1.00 36.09  ? 467 TYR B CZ  1 
ATOM   5433  O OH  . TYR B 2 467 ? 112.607 113.688 140.301 1.00 39.92  ? 467 TYR B OH  1 
ATOM   5434  N N   . TRP B 2 468 ? 109.149 108.304 142.795 1.00 47.79  ? 468 TRP B N   1 
ATOM   5435  C CA  . TRP B 2 468 ? 109.904 107.340 142.000 1.00 49.04  ? 468 TRP B CA  1 
ATOM   5436  C C   . TRP B 2 468 ? 108.985 106.437 141.186 1.00 48.35  ? 468 TRP B C   1 
ATOM   5437  O O   . TRP B 2 468 ? 109.298 106.106 140.039 1.00 53.91  ? 468 TRP B O   1 
ATOM   5438  C CB  . TRP B 2 468 ? 110.833 106.515 142.892 1.00 46.71  ? 468 TRP B CB  1 
ATOM   5439  C CG  . TRP B 2 468 ? 111.913 107.331 143.547 1.00 49.83  ? 468 TRP B CG  1 
ATOM   5440  C CD1 . TRP B 2 468 ? 112.035 107.619 144.872 1.00 49.22  ? 468 TRP B CD1 1 
ATOM   5441  C CD2 . TRP B 2 468 ? 113.016 107.975 142.894 1.00 51.04  ? 468 TRP B CD2 1 
ATOM   5442  N NE1 . TRP B 2 468 ? 113.148 108.395 145.089 1.00 50.96  ? 468 TRP B NE1 1 
ATOM   5443  C CE2 . TRP B 2 468 ? 113.767 108.628 143.889 1.00 49.10  ? 468 TRP B CE2 1 
ATOM   5444  C CE3 . TRP B 2 468 ? 113.441 108.059 141.564 1.00 44.67  ? 468 TRP B CE3 1 
ATOM   5445  C CZ2 . TRP B 2 468 ? 114.919 109.354 143.599 1.00 39.39  ? 468 TRP B CZ2 1 
ATOM   5446  C CZ3 . TRP B 2 468 ? 114.585 108.782 141.279 1.00 37.23  ? 468 TRP B CZ3 1 
ATOM   5447  C CH2 . TRP B 2 468 ? 115.311 109.419 142.291 1.00 33.85  ? 468 TRP B CH2 1 
ATOM   5448  N N   . LEU B 2 469 ? 107.847 106.032 141.753 1.00 44.33  ? 469 LEU B N   1 
ATOM   5449  C CA  . LEU B 2 469 ? 106.888 105.249 140.979 1.00 45.44  ? 469 LEU B CA  1 
ATOM   5450  C C   . LEU B 2 469 ? 106.354 106.042 139.794 1.00 45.18  ? 469 LEU B C   1 
ATOM   5451  O O   . LEU B 2 469 ? 106.229 105.507 138.686 1.00 47.13  ? 469 LEU B O   1 
ATOM   5452  C CB  . LEU B 2 469 ? 105.739 104.780 141.871 1.00 50.63  ? 469 LEU B CB  1 
ATOM   5453  C CG  . LEU B 2 469 ? 106.063 103.648 142.845 1.00 51.34  ? 469 LEU B CG  1 
ATOM   5454  C CD1 . LEU B 2 469 ? 104.832 103.269 143.648 1.00 50.88  ? 469 LEU B CD1 1 
ATOM   5455  C CD2 . LEU B 2 469 ? 106.607 102.445 142.094 1.00 46.09  ? 469 LEU B CD2 1 
ATOM   5456  N N   . TYR B 2 470 ? 106.025 107.317 140.007 1.00 42.37  ? 470 TYR B N   1 
ATOM   5457  C CA  . TYR B 2 470 ? 105.497 108.133 138.918 1.00 47.25  ? 470 TYR B CA  1 
ATOM   5458  C C   . TYR B 2 470 ? 106.532 108.335 137.815 1.00 49.53  ? 470 TYR B C   1 
ATOM   5459  O O   . TYR B 2 470 ? 106.195 108.276 136.627 1.00 48.42  ? 470 TYR B O   1 
ATOM   5460  C CB  . TYR B 2 470 ? 105.018 109.477 139.465 1.00 45.86  ? 470 TYR B CB  1 
ATOM   5461  C CG  . TYR B 2 470 ? 104.504 110.439 138.417 1.00 49.06  ? 470 TYR B CG  1 
ATOM   5462  C CD1 . TYR B 2 470 ? 103.176 110.413 138.019 1.00 49.15  ? 470 TYR B CD1 1 
ATOM   5463  C CD2 . TYR B 2 470 ? 105.342 111.384 137.839 1.00 51.13  ? 470 TYR B CD2 1 
ATOM   5464  C CE1 . TYR B 2 470 ? 102.697 111.291 137.067 1.00 58.06  ? 470 TYR B CE1 1 
ATOM   5465  C CE2 . TYR B 2 470 ? 104.872 112.267 136.886 1.00 52.34  ? 470 TYR B CE2 1 
ATOM   5466  C CZ  . TYR B 2 470 ? 103.549 112.216 136.505 1.00 57.33  ? 470 TYR B CZ  1 
ATOM   5467  O OH  . TYR B 2 470 ? 103.075 113.093 135.558 1.00 58.46  ? 470 TYR B OH  1 
ATOM   5468  N N   . TYR B 2 471 ? 107.793 108.569 138.181 1.00 48.65  ? 471 TYR B N   1 
ATOM   5469  C CA  . TYR B 2 471 ? 108.839 108.858 137.206 1.00 45.53  ? 471 TYR B CA  1 
ATOM   5470  C C   . TYR B 2 471 ? 109.684 107.647 136.826 1.00 48.60  ? 471 TYR B C   1 
ATOM   5471  O O   . TYR B 2 471 ? 110.598 107.786 136.008 1.00 50.02  ? 471 TYR B O   1 
ATOM   5472  C CB  . TYR B 2 471 ? 109.752 109.974 137.723 1.00 42.36  ? 471 TYR B CB  1 
ATOM   5473  C CG  . TYR B 2 471 ? 109.110 111.341 137.709 1.00 42.89  ? 471 TYR B CG  1 
ATOM   5474  C CD1 . TYR B 2 471 ? 108.790 111.965 136.511 1.00 45.91  ? 471 TYR B CD1 1 
ATOM   5475  C CD2 . TYR B 2 471 ? 108.827 112.010 138.891 1.00 43.03  ? 471 TYR B CD2 1 
ATOM   5476  C CE1 . TYR B 2 471 ? 108.203 113.215 136.491 1.00 45.41  ? 471 TYR B CE1 1 
ATOM   5477  C CE2 . TYR B 2 471 ? 108.240 113.260 138.880 1.00 44.28  ? 471 TYR B CE2 1 
ATOM   5478  C CZ  . TYR B 2 471 ? 107.931 113.858 137.678 1.00 46.00  ? 471 TYR B CZ  1 
ATOM   5479  O OH  . TYR B 2 471 ? 107.348 115.103 137.664 1.00 48.60  ? 471 TYR B OH  1 
ATOM   5480  N N   . VAL B 2 472 ? 109.402 106.469 137.377 1.00 52.28  ? 472 VAL B N   1 
ATOM   5481  C CA  . VAL B 2 472 ? 110.121 105.250 137.000 1.00 52.78  ? 472 VAL B CA  1 
ATOM   5482  C C   . VAL B 2 472 ? 109.146 104.081 136.955 1.00 51.24  ? 472 VAL B C   1 
ATOM   5483  O O   . VAL B 2 472 ? 107.938 104.271 136.822 1.00 46.59  ? 472 VAL B O   1 
ATOM   5484  C CB  . VAL B 2 472 ? 111.291 104.921 137.963 1.00 50.87  ? 472 VAL B CB  1 
ATOM   5485  C CG1 . VAL B 2 472 ? 112.077 103.730 137.444 1.00 46.84  ? 472 VAL B CG1 1 
ATOM   5486  C CG2 . VAL B 2 472 ? 112.216 106.113 138.155 1.00 44.49  ? 472 VAL B CG2 1 
ATOM   5487  N N   . MET C 2 34  ? 141.760 160.716 82.191  1.00 115.07 ? 9   MET C N   1 
ATOM   5488  C CA  . MET C 2 34  ? 141.738 159.408 82.835  1.00 118.91 ? 9   MET C CA  1 
ATOM   5489  C C   . MET C 2 34  ? 142.204 158.311 81.886  1.00 118.78 ? 9   MET C C   1 
ATOM   5490  O O   . MET C 2 34  ? 142.723 157.283 82.321  1.00 116.42 ? 9   MET C O   1 
ATOM   5491  C CB  . MET C 2 34  ? 140.332 159.090 83.344  1.00 129.15 ? 9   MET C CB  1 
ATOM   5492  C CG  . MET C 2 34  ? 139.803 160.061 84.383  1.00 134.01 ? 9   MET C CG  1 
ATOM   5493  S SD  . MET C 2 34  ? 138.136 159.631 84.914  1.00 145.88 ? 9   MET C SD  1 
ATOM   5494  C CE  . MET C 2 34  ? 138.409 157.982 85.555  1.00 138.98 ? 9   MET C CE  1 
ATOM   5495  N N   . SER C 2 35  ? 142.007 158.536 80.584  1.00 120.62 ? 10  SER C N   1 
ATOM   5496  C CA  . SER C 2 35  ? 142.408 157.546 79.590  1.00 115.80 ? 10  SER C CA  1 
ATOM   5497  C C   . SER C 2 35  ? 143.916 157.332 79.596  1.00 117.49 ? 10  SER C C   1 
ATOM   5498  O O   . SER C 2 35  ? 144.391 156.201 79.438  1.00 116.68 ? 10  SER C O   1 
ATOM   5499  C CB  . SER C 2 35  ? 141.932 157.973 78.202  1.00 107.06 ? 10  SER C CB  1 
ATOM   5500  O OG  . SER C 2 35  ? 142.511 159.209 77.823  1.00 102.01 ? 10  SER C OG  1 
ATOM   5501  N N   . PHE C 2 36  ? 144.685 158.410 79.765  1.00 116.14 ? 11  PHE C N   1 
ATOM   5502  C CA  . PHE C 2 36  ? 146.140 158.294 79.797  1.00 111.48 ? 11  PHE C CA  1 
ATOM   5503  C C   . PHE C 2 36  ? 146.601 157.404 80.945  1.00 110.52 ? 11  PHE C C   1 
ATOM   5504  O O   . PHE C 2 36  ? 147.453 156.526 80.762  1.00 108.35 ? 11  PHE C O   1 
ATOM   5505  C CB  . PHE C 2 36  ? 146.773 159.681 79.899  1.00 107.82 ? 11  PHE C CB  1 
ATOM   5506  C CG  . PHE C 2 36  ? 148.254 159.654 80.140  1.00 113.92 ? 11  PHE C CG  1 
ATOM   5507  C CD1 . PHE C 2 36  ? 149.102 159.013 79.254  1.00 115.67 ? 11  PHE C CD1 1 
ATOM   5508  C CD2 . PHE C 2 36  ? 148.798 160.276 81.251  1.00 111.82 ? 11  PHE C CD2 1 
ATOM   5509  C CE1 . PHE C 2 36  ? 150.466 158.988 79.474  1.00 113.98 ? 11  PHE C CE1 1 
ATOM   5510  C CE2 . PHE C 2 36  ? 150.161 160.256 81.475  1.00 112.84 ? 11  PHE C CE2 1 
ATOM   5511  C CZ  . PHE C 2 36  ? 150.996 159.611 80.586  1.00 113.89 ? 11  PHE C CZ  1 
ATOM   5512  N N   . VAL C 2 37  ? 146.051 157.618 82.142  1.00 110.57 ? 12  VAL C N   1 
ATOM   5513  C CA  . VAL C 2 37  ? 146.405 156.774 83.279  1.00 107.22 ? 12  VAL C CA  1 
ATOM   5514  C C   . VAL C 2 37  ? 145.873 155.359 83.083  1.00 104.10 ? 12  VAL C C   1 
ATOM   5515  O O   . VAL C 2 37  ? 146.529 154.378 83.454  1.00 103.53 ? 12  VAL C O   1 
ATOM   5516  C CB  . VAL C 2 37  ? 145.889 157.399 84.589  1.00 102.30 ? 12  VAL C CB  1 
ATOM   5517  C CG1 . VAL C 2 37  ? 146.234 156.516 85.778  1.00 92.18  ? 12  VAL C CG1 1 
ATOM   5518  C CG2 . VAL C 2 37  ? 146.464 158.793 84.773  1.00 100.63 ? 12  VAL C CG2 1 
ATOM   5519  N N   . LYS C 2 38  ? 144.680 155.229 82.497  1.00 103.97 ? 13  LYS C N   1 
ATOM   5520  C CA  . LYS C 2 38  ? 144.120 153.907 82.232  1.00 104.58 ? 13  LYS C CA  1 
ATOM   5521  C C   . LYS C 2 38  ? 145.031 153.097 81.318  1.00 106.45 ? 13  LYS C C   1 
ATOM   5522  O O   . LYS C 2 38  ? 145.294 151.916 81.572  1.00 106.30 ? 13  LYS C O   1 
ATOM   5523  C CB  . LYS C 2 38  ? 142.725 154.044 81.622  1.00 109.93 ? 13  LYS C CB  1 
ATOM   5524  C CG  . LYS C 2 38  ? 142.128 152.738 81.122  1.00 109.58 ? 13  LYS C CG  1 
ATOM   5525  C CD  . LYS C 2 38  ? 140.718 152.952 80.595  1.00 111.94 ? 13  LYS C CD  1 
ATOM   5526  C CE  . LYS C 2 38  ? 140.209 151.729 79.851  1.00 111.55 ? 13  LYS C CE  1 
ATOM   5527  N NZ  . LYS C 2 38  ? 140.206 150.518 80.715  1.00 115.52 ? 13  LYS C NZ  1 
ATOM   5528  N N   . GLU C 2 39  ? 145.522 153.719 80.244  1.00 109.15 ? 14  GLU C N   1 
ATOM   5529  C CA  . GLU C 2 39  ? 146.461 153.037 79.362  1.00 107.68 ? 14  GLU C CA  1 
ATOM   5530  C C   . GLU C 2 39  ? 147.814 152.829 80.031  1.00 104.33 ? 14  GLU C C   1 
ATOM   5531  O O   . GLU C 2 39  ? 148.493 151.834 79.754  1.00 100.36 ? 14  GLU C O   1 
ATOM   5532  C CB  . GLU C 2 39  ? 146.624 153.824 78.062  1.00 111.06 ? 14  GLU C CB  1 
ATOM   5533  C CG  . GLU C 2 39  ? 145.347 153.926 77.241  1.00 118.74 ? 14  GLU C CG  1 
ATOM   5534  C CD  . GLU C 2 39  ? 145.517 154.773 75.994  1.00 129.87 ? 14  GLU C CD  1 
ATOM   5535  O OE1 . GLU C 2 39  ? 146.674 155.047 75.611  1.00 137.85 ? 14  GLU C OE1 1 
ATOM   5536  O OE2 . GLU C 2 39  ? 144.493 155.166 75.398  1.00 124.80 ? 14  GLU C OE2 1 
ATOM   5537  N N   . THR C 2 40  ? 148.220 153.753 80.905  1.00 104.70 ? 15  THR C N   1 
ATOM   5538  C CA  . THR C 2 40  ? 149.459 153.573 81.657  1.00 98.58  ? 15  THR C CA  1 
ATOM   5539  C C   . THR C 2 40  ? 149.401 152.330 82.536  1.00 97.59  ? 15  THR C C   1 
ATOM   5540  O O   . THR C 2 40  ? 150.362 151.555 82.592  1.00 95.63  ? 15  THR C O   1 
ATOM   5541  C CB  . THR C 2 40  ? 149.744 154.811 82.506  1.00 98.83  ? 15  THR C CB  1 
ATOM   5542  O OG1 . THR C 2 40  ? 149.780 155.971 81.666  1.00 102.79 ? 15  THR C OG1 1 
ATOM   5543  C CG2 . THR C 2 40  ? 151.078 154.671 83.218  1.00 92.80  ? 15  THR C CG2 1 
ATOM   5544  N N   . VAL C 2 41  ? 148.276 152.117 83.220  1.00 101.40 ? 16  VAL C N   1 
ATOM   5545  C CA  . VAL C 2 41  ? 148.145 150.956 84.096  1.00 95.04  ? 16  VAL C CA  1 
ATOM   5546  C C   . VAL C 2 41  ? 148.079 149.673 83.276  1.00 95.84  ? 16  VAL C C   1 
ATOM   5547  O O   . VAL C 2 41  ? 148.754 148.685 83.591  1.00 88.42  ? 16  VAL C O   1 
ATOM   5548  C CB  . VAL C 2 41  ? 146.914 151.109 85.007  1.00 83.00  ? 16  VAL C CB  1 
ATOM   5549  C CG1 . VAL C 2 41  ? 146.682 149.836 85.803  1.00 82.25  ? 16  VAL C CG1 1 
ATOM   5550  C CG2 . VAL C 2 41  ? 147.092 152.300 85.934  1.00 77.07  ? 16  VAL C CG2 1 
ATOM   5551  N N   . ASP C 2 42  ? 147.257 149.661 82.222  1.00 101.41 ? 17  ASP C N   1 
ATOM   5552  C CA  . ASP C 2 42  ? 147.183 148.486 81.359  1.00 101.03 ? 17  ASP C CA  1 
ATOM   5553  C C   . ASP C 2 42  ? 148.545 148.129 80.778  1.00 99.20  ? 17  ASP C C   1 
ATOM   5554  O O   . ASP C 2 42  ? 148.824 146.952 80.528  1.00 95.49  ? 17  ASP C O   1 
ATOM   5555  C CB  . ASP C 2 42  ? 146.178 148.723 80.232  1.00 105.06 ? 17  ASP C CB  1 
ATOM   5556  C CG  . ASP C 2 42  ? 144.740 148.609 80.698  1.00 116.02 ? 17  ASP C CG  1 
ATOM   5557  O OD1 . ASP C 2 42  ? 144.480 147.841 81.647  1.00 123.14 ? 17  ASP C OD1 1 
ATOM   5558  O OD2 . ASP C 2 42  ? 143.870 149.289 80.114  1.00 120.06 ? 17  ASP C OD2 1 
ATOM   5559  N N   . LYS C 2 43  ? 149.399 149.130 80.550  1.00 99.23  ? 18  LYS C N   1 
ATOM   5560  C CA  . LYS C 2 43  ? 150.757 148.861 80.088  1.00 98.93  ? 18  LYS C CA  1 
ATOM   5561  C C   . LYS C 2 43  ? 151.548 148.080 81.130  1.00 98.73  ? 18  LYS C C   1 
ATOM   5562  O O   . LYS C 2 43  ? 152.281 147.142 80.793  1.00 97.43  ? 18  LYS C O   1 
ATOM   5563  C CB  . LYS C 2 43  ? 151.464 150.174 79.749  1.00 89.34  ? 18  LYS C CB  1 
ATOM   5564  C CG  . LYS C 2 43  ? 152.866 150.002 79.191  1.00 86.15  ? 18  LYS C CG  1 
ATOM   5565  C CD  . LYS C 2 43  ? 153.468 151.340 78.795  1.00 87.42  ? 18  LYS C CD  1 
ATOM   5566  C CE  . LYS C 2 43  ? 154.926 151.191 78.389  1.00 80.91  ? 18  LYS C CE  1 
ATOM   5567  N NZ  . LYS C 2 43  ? 155.557 152.507 78.098  1.00 66.85  ? 18  LYS C NZ  1 
ATOM   5568  N N   . LEU C 2 44  ? 151.416 148.460 82.403  1.00 94.12  ? 19  LEU C N   1 
ATOM   5569  C CA  . LEU C 2 44  ? 152.157 147.800 83.473  1.00 91.45  ? 19  LEU C CA  1 
ATOM   5570  C C   . LEU C 2 44  ? 151.771 146.331 83.600  1.00 92.46  ? 19  LEU C C   1 
ATOM   5571  O O   . LEU C 2 44  ? 152.637 145.449 83.613  1.00 92.28  ? 19  LEU C O   1 
ATOM   5572  C CB  . LEU C 2 44  ? 151.929 148.530 84.796  1.00 86.58  ? 19  LEU C CB  1 
ATOM   5573  C CG  . LEU C 2 44  ? 152.425 149.973 84.871  1.00 79.73  ? 19  LEU C CG  1 
ATOM   5574  C CD1 . LEU C 2 44  ? 152.083 150.584 86.219  1.00 77.31  ? 19  LEU C CD1 1 
ATOM   5575  C CD2 . LEU C 2 44  ? 153.921 150.036 84.613  1.00 76.60  ? 19  LEU C CD2 1 
ATOM   5576  N N   . LEU C 2 45  ? 150.470 146.047 83.689  1.00 86.89  ? 20  LEU C N   1 
ATOM   5577  C CA  . LEU C 2 45  ? 150.037 144.674 83.928  1.00 85.99  ? 20  LEU C CA  1 
ATOM   5578  C C   . LEU C 2 45  ? 150.265 143.785 82.715  1.00 89.12  ? 20  LEU C C   1 
ATOM   5579  O O   . LEU C 2 45  ? 150.522 142.587 82.873  1.00 86.03  ? 20  LEU C O   1 
ATOM   5580  C CB  . LEU C 2 45  ? 148.563 144.649 84.329  1.00 90.86  ? 20  LEU C CB  1 
ATOM   5581  C CG  . LEU C 2 45  ? 148.150 145.595 85.455  1.00 93.26  ? 20  LEU C CG  1 
ATOM   5582  C CD1 . LEU C 2 45  ? 146.728 145.299 85.875  1.00 82.53  ? 20  LEU C CD1 1 
ATOM   5583  C CD2 . LEU C 2 45  ? 149.092 145.466 86.638  1.00 86.56  ? 20  LEU C CD2 1 
ATOM   5584  N N   . LYS C 2 46  ? 150.135 144.329 81.509  1.00 96.29  ? 21  LYS C N   1 
ATOM   5585  C CA  . LYS C 2 46  ? 150.358 143.531 80.311  1.00 101.13 ? 21  LYS C CA  1 
ATOM   5586  C C   . LYS C 2 46  ? 151.773 142.967 80.334  1.00 99.16  ? 21  LYS C C   1 
ATOM   5587  O O   . LYS C 2 46  ? 152.750 143.722 80.371  1.00 86.29  ? 21  LYS C O   1 
ATOM   5588  C CB  . LYS C 2 46  ? 150.132 144.377 79.060  1.00 101.94 ? 21  LYS C CB  1 
ATOM   5589  C CG  . LYS C 2 46  ? 150.245 143.603 77.758  1.00 105.35 ? 21  LYS C CG  1 
ATOM   5590  C CD  . LYS C 2 46  ? 150.229 144.535 76.558  1.00 101.98 ? 21  LYS C CD  1 
ATOM   5591  C CE  . LYS C 2 46  ? 150.466 143.771 75.266  1.00 97.42  ? 21  LYS C CE  1 
ATOM   5592  N NZ  . LYS C 2 46  ? 150.607 144.683 74.099  1.00 98.80  ? 21  LYS C NZ  1 
ATOM   5593  N N   . GLY C 2 47  ? 151.884 141.641 80.312  1.00 103.53 ? 22  GLY C N   1 
ATOM   5594  C CA  . GLY C 2 47  ? 153.171 140.993 80.439  1.00 99.39  ? 22  GLY C CA  1 
ATOM   5595  C C   . GLY C 2 47  ? 153.676 140.813 81.855  1.00 96.66  ? 22  GLY C C   1 
ATOM   5596  O O   . GLY C 2 47  ? 154.765 140.252 82.035  1.00 92.61  ? 22  GLY C O   1 
ATOM   5597  N N   . TYR C 2 48  ? 152.937 141.272 82.862  1.00 95.14  ? 23  TYR C N   1 
ATOM   5598  C CA  . TYR C 2 48  ? 153.365 141.096 84.244  1.00 84.14  ? 23  TYR C CA  1 
ATOM   5599  C C   . TYR C 2 48  ? 153.276 139.627 84.637  1.00 80.15  ? 23  TYR C C   1 
ATOM   5600  O O   . TYR C 2 48  ? 152.369 138.907 84.213  1.00 81.54  ? 23  TYR C O   1 
ATOM   5601  C CB  . TYR C 2 48  ? 152.498 141.949 85.170  1.00 80.34  ? 23  TYR C CB  1 
ATOM   5602  C CG  . TYR C 2 48  ? 152.992 142.093 86.591  1.00 75.24  ? 23  TYR C CG  1 
ATOM   5603  C CD1 . TYR C 2 48  ? 152.688 141.140 87.554  1.00 71.17  ? 23  TYR C CD1 1 
ATOM   5604  C CD2 . TYR C 2 48  ? 153.743 143.194 86.976  1.00 78.17  ? 23  TYR C CD2 1 
ATOM   5605  C CE1 . TYR C 2 48  ? 153.128 141.274 88.856  1.00 70.72  ? 23  TYR C CE1 1 
ATOM   5606  C CE2 . TYR C 2 48  ? 154.188 143.337 88.276  1.00 76.54  ? 23  TYR C CE2 1 
ATOM   5607  C CZ  . TYR C 2 48  ? 153.878 142.375 89.211  1.00 72.81  ? 23  TYR C CZ  1 
ATOM   5608  O OH  . TYR C 2 48  ? 154.319 142.515 90.506  1.00 67.39  ? 23  TYR C OH  1 
ATOM   5609  N N   . ASP C 2 49  ? 154.226 139.184 85.457  1.00 73.04  ? 24  ASP C N   1 
ATOM   5610  C CA  . ASP C 2 49  ? 154.285 137.803 85.934  1.00 72.52  ? 24  ASP C CA  1 
ATOM   5611  C C   . ASP C 2 49  ? 154.297 137.821 87.459  1.00 71.32  ? 24  ASP C C   1 
ATOM   5612  O O   . ASP C 2 49  ? 155.336 138.081 88.074  1.00 68.35  ? 24  ASP C O   1 
ATOM   5613  C CB  . ASP C 2 49  ? 155.507 137.082 85.369  1.00 72.03  ? 24  ASP C CB  1 
ATOM   5614  C CG  . ASP C 2 49  ? 155.486 135.590 85.646  1.00 73.03  ? 24  ASP C CG  1 
ATOM   5615  O OD1 . ASP C 2 49  ? 154.518 135.107 86.269  1.00 72.72  ? 24  ASP C OD1 1 
ATOM   5616  O OD2 . ASP C 2 49  ? 156.433 134.895 85.224  1.00 71.44  ? 24  ASP C OD2 1 
ATOM   5617  N N   . ILE C 2 50  ? 153.142 137.546 88.071  1.00 68.72  ? 25  ILE C N   1 
ATOM   5618  C CA  . ILE C 2 50  ? 153.058 137.550 89.526  1.00 65.02  ? 25  ILE C CA  1 
ATOM   5619  C C   . ILE C 2 50  ? 153.884 136.424 90.140  1.00 66.36  ? 25  ILE C C   1 
ATOM   5620  O O   . ILE C 2 50  ? 154.220 136.479 91.328  1.00 63.47  ? 25  ILE C O   1 
ATOM   5621  C CB  . ILE C 2 50  ? 151.578 137.452 89.950  1.00 60.97  ? 25  ILE C CB  1 
ATOM   5622  C CG1 . ILE C 2 50  ? 151.425 137.462 91.474  1.00 55.82  ? 25  ILE C CG1 1 
ATOM   5623  C CG2 . ILE C 2 50  ? 150.933 136.212 89.350  1.00 57.23  ? 25  ILE C CG2 1 
ATOM   5624  C CD1 . ILE C 2 50  ? 149.993 137.332 91.946  1.00 59.15  ? 25  ILE C CD1 1 
ATOM   5625  N N   . ARG C 2 51  ? 154.261 135.419 89.350  1.00 67.44  ? 26  ARG C N   1 
ATOM   5626  C CA  . ARG C 2 51  ? 154.990 134.276 89.884  1.00 64.57  ? 26  ARG C CA  1 
ATOM   5627  C C   . ARG C 2 51  ? 156.472 134.553 90.095  1.00 65.91  ? 26  ARG C C   1 
ATOM   5628  O O   . ARG C 2 51  ? 157.159 133.718 90.693  1.00 70.37  ? 26  ARG C O   1 
ATOM   5629  C CB  . ARG C 2 51  ? 154.817 133.062 88.968  1.00 56.29  ? 26  ARG C CB  1 
ATOM   5630  C CG  . ARG C 2 51  ? 153.368 132.688 88.712  1.00 54.37  ? 26  ARG C CG  1 
ATOM   5631  C CD  . ARG C 2 51  ? 153.250 131.598 87.663  1.00 64.83  ? 26  ARG C CD  1 
ATOM   5632  N NE  . ARG C 2 51  ? 153.722 132.037 86.356  1.00 75.12  ? 26  ARG C NE  1 
ATOM   5633  C CZ  . ARG C 2 51  ? 153.674 131.296 85.258  1.00 75.74  ? 26  ARG C CZ  1 
ATOM   5634  N NH1 . ARG C 2 51  ? 153.168 130.074 85.270  1.00 69.11  ? 26  ARG C NH1 1 
ATOM   5635  N NH2 . ARG C 2 51  ? 154.140 131.796 84.117  1.00 78.27  ? 26  ARG C NH2 1 
ATOM   5636  N N   . LEU C 2 52  ? 156.983 135.688 89.627  1.00 60.74  ? 27  LEU C N   1 
ATOM   5637  C CA  . LEU C 2 52  ? 158.395 136.021 89.755  1.00 62.07  ? 27  LEU C CA  1 
ATOM   5638  C C   . LEU C 2 52  ? 158.571 137.232 90.658  1.00 68.63  ? 27  LEU C C   1 
ATOM   5639  O O   . LEU C 2 52  ? 157.878 138.241 90.497  1.00 73.80  ? 27  LEU C O   1 
ATOM   5640  C CB  . LEU C 2 52  ? 159.017 136.302 88.387  1.00 68.48  ? 27  LEU C CB  1 
ATOM   5641  C CG  . LEU C 2 52  ? 158.851 135.203 87.340  1.00 72.63  ? 27  LEU C CG  1 
ATOM   5642  C CD1 . LEU C 2 52  ? 159.587 135.564 86.058  1.00 75.40  ? 27  LEU C CD1 1 
ATOM   5643  C CD2 . LEU C 2 52  ? 159.334 133.879 87.891  1.00 74.14  ? 27  LEU C CD2 1 
ATOM   5644  N N   . ARG C 2 53  ? 159.504 137.127 91.600  1.00 66.65  ? 28  ARG C N   1 
ATOM   5645  C CA  . ARG C 2 53  ? 159.788 138.218 92.509  1.00 66.83  ? 28  ARG C CA  1 
ATOM   5646  C C   . ARG C 2 53  ? 160.508 139.345 91.770  1.00 76.56  ? 28  ARG C C   1 
ATOM   5647  O O   . ARG C 2 53  ? 161.115 139.122 90.719  1.00 75.19  ? 28  ARG C O   1 
ATOM   5648  C CB  . ARG C 2 53  ? 160.634 137.721 93.677  1.00 71.48  ? 28  ARG C CB  1 
ATOM   5649  C CG  . ARG C 2 53  ? 162.058 137.365 93.289  1.00 86.30  ? 28  ARG C CG  1 
ATOM   5650  C CD  . ARG C 2 53  ? 162.915 137.089 94.507  1.00 84.91  ? 28  ARG C CD  1 
ATOM   5651  N NE  . ARG C 2 53  ? 164.292 136.782 94.138  1.00 81.41  ? 28  ARG C NE  1 
ATOM   5652  C CZ  . ARG C 2 53  ? 165.214 137.693 93.866  1.00 80.13  ? 28  ARG C CZ  1 
ATOM   5653  N NH1 . ARG C 2 53  ? 164.929 138.985 93.861  1.00 80.57  ? 28  ARG C NH1 1 
ATOM   5654  N NH2 . ARG C 2 53  ? 166.452 137.298 93.582  1.00 83.86  ? 28  ARG C NH2 1 
ATOM   5655  N N   . PRO C 2 54  ? 160.435 140.571 92.289  1.00 76.34  ? 29  PRO C N   1 
ATOM   5656  C CA  . PRO C 2 54  ? 161.227 141.662 91.707  1.00 81.50  ? 29  PRO C CA  1 
ATOM   5657  C C   . PRO C 2 54  ? 162.710 141.324 91.717  1.00 89.05  ? 29  PRO C C   1 
ATOM   5658  O O   . PRO C 2 54  ? 163.214 140.700 92.653  1.00 90.74  ? 29  PRO C O   1 
ATOM   5659  C CB  . PRO C 2 54  ? 160.917 142.853 92.619  1.00 77.11  ? 29  PRO C CB  1 
ATOM   5660  C CG  . PRO C 2 54  ? 159.604 142.534 93.232  1.00 70.30  ? 29  PRO C CG  1 
ATOM   5661  C CD  . PRO C 2 54  ? 159.535 141.042 93.355  1.00 68.20  ? 29  PRO C CD  1 
ATOM   5662  N N   . ASP C 2 55  ? 163.408 141.749 90.664  1.00 92.54  ? 30  ASP C N   1 
ATOM   5663  C CA  . ASP C 2 55  ? 164.826 141.440 90.489  1.00 96.62  ? 30  ASP C CA  1 
ATOM   5664  C C   . ASP C 2 55  ? 165.060 139.933 90.558  1.00 93.27  ? 30  ASP C C   1 
ATOM   5665  O O   . ASP C 2 55  ? 165.974 139.446 91.228  1.00 90.67  ? 30  ASP C O   1 
ATOM   5666  C CB  . ASP C 2 55  ? 165.684 142.184 91.514  1.00 97.57  ? 30  ASP C CB  1 
ATOM   5667  C CG  . ASP C 2 55  ? 165.706 143.681 91.276  1.00 103.97 ? 30  ASP C CG  1 
ATOM   5668  O OD1 . ASP C 2 55  ? 165.033 144.142 90.330  1.00 100.93 ? 30  ASP C OD1 1 
ATOM   5669  O OD2 . ASP C 2 55  ? 166.395 144.396 92.033  1.00 109.61 ? 30  ASP C OD2 1 
ATOM   5670  N N   . PHE C 2 56  ? 164.197 139.191 89.864  1.00 92.72  ? 31  PHE C N   1 
ATOM   5671  C CA  . PHE C 2 56  ? 164.266 137.735 89.871  1.00 91.79  ? 31  PHE C CA  1 
ATOM   5672  C C   . PHE C 2 56  ? 165.618 137.256 89.359  1.00 97.98  ? 31  PHE C C   1 
ATOM   5673  O O   . PHE C 2 56  ? 166.085 137.678 88.297  1.00 98.71  ? 31  PHE C O   1 
ATOM   5674  C CB  . PHE C 2 56  ? 163.140 137.154 89.017  1.00 83.01  ? 31  PHE C CB  1 
ATOM   5675  C CG  . PHE C 2 56  ? 163.101 135.655 89.004  1.00 77.26  ? 31  PHE C CG  1 
ATOM   5676  C CD1 . PHE C 2 56  ? 162.658 134.952 90.111  1.00 72.25  ? 31  PHE C CD1 1 
ATOM   5677  C CD2 . PHE C 2 56  ? 163.509 134.947 87.887  1.00 82.18  ? 31  PHE C CD2 1 
ATOM   5678  C CE1 . PHE C 2 56  ? 162.619 133.574 90.104  1.00 71.47  ? 31  PHE C CE1 1 
ATOM   5679  C CE2 . PHE C 2 56  ? 163.474 133.568 87.875  1.00 79.96  ? 31  PHE C CE2 1 
ATOM   5680  C CZ  . PHE C 2 56  ? 163.028 132.881 88.986  1.00 72.00  ? 31  PHE C CZ  1 
ATOM   5681  N N   . GLY C 2 57  ? 166.244 136.367 90.129  1.00 96.37  ? 32  GLY C N   1 
ATOM   5682  C CA  . GLY C 2 57  ? 167.569 135.868 89.841  1.00 92.85  ? 32  GLY C CA  1 
ATOM   5683  C C   . GLY C 2 57  ? 168.693 136.814 90.197  1.00 97.41  ? 32  GLY C C   1 
ATOM   5684  O O   . GLY C 2 57  ? 169.864 136.428 90.088  1.00 102.55 ? 32  GLY C O   1 
ATOM   5685  N N   . GLY C 2 58  ? 168.380 138.034 90.624  1.00 96.45  ? 33  GLY C N   1 
ATOM   5686  C CA  . GLY C 2 58  ? 169.377 138.997 91.021  1.00 95.44  ? 33  GLY C CA  1 
ATOM   5687  C C   . GLY C 2 58  ? 169.487 139.081 92.529  1.00 94.17  ? 33  GLY C C   1 
ATOM   5688  O O   . GLY C 2 58  ? 169.241 138.107 93.249  1.00 86.21  ? 33  GLY C O   1 
ATOM   5689  N N   . PRO C 2 59  ? 169.870 140.251 93.037  1.00 96.29  ? 34  PRO C N   1 
ATOM   5690  C CA  . PRO C 2 59  ? 169.958 140.421 94.483  1.00 87.08  ? 34  PRO C CA  1 
ATOM   5691  C C   . PRO C 2 59  ? 168.591 140.269 95.116  1.00 85.98  ? 34  PRO C C   1 
ATOM   5692  O O   . PRO C 2 59  ? 167.557 140.511 94.467  1.00 94.20  ? 34  PRO C O   1 
ATOM   5693  C CB  . PRO C 2 59  ? 170.497 141.851 94.639  1.00 86.46  ? 34  PRO C CB  1 
ATOM   5694  C CG  . PRO C 2 59  ? 171.128 142.177 93.325  1.00 92.78  ? 34  PRO C CG  1 
ATOM   5695  C CD  . PRO C 2 59  ? 170.324 141.443 92.303  1.00 96.42  ? 34  PRO C CD  1 
ATOM   5696  N N   . PRO C 2 60  ? 168.534 139.856 96.382  1.00 81.89  ? 35  PRO C N   1 
ATOM   5697  C CA  . PRO C 2 60  ? 167.235 139.708 97.046  1.00 82.80  ? 35  PRO C CA  1 
ATOM   5698  C C   . PRO C 2 60  ? 166.480 141.028 97.105  1.00 82.38  ? 35  PRO C C   1 
ATOM   5699  O O   . PRO C 2 60  ? 167.070 142.102 97.239  1.00 87.11  ? 35  PRO C O   1 
ATOM   5700  C CB  . PRO C 2 60  ? 167.607 139.213 98.448  1.00 80.93  ? 35  PRO C CB  1 
ATOM   5701  C CG  . PRO C 2 60  ? 169.004 139.682 98.655  1.00 80.74  ? 35  PRO C CG  1 
ATOM   5702  C CD  . PRO C 2 60  ? 169.657 139.619 97.304  1.00 82.35  ? 35  PRO C CD  1 
ATOM   5703  N N   . VAL C 2 61  ? 165.159 140.935 96.993  1.00 76.32  ? 36  VAL C N   1 
ATOM   5704  C CA  . VAL C 2 61  ? 164.301 142.112 97.078  1.00 72.10  ? 36  VAL C CA  1 
ATOM   5705  C C   . VAL C 2 61  ? 164.131 142.490 98.545  1.00 64.52  ? 36  VAL C C   1 
ATOM   5706  O O   . VAL C 2 61  ? 163.702 141.672 99.365  1.00 61.17  ? 36  VAL C O   1 
ATOM   5707  C CB  . VAL C 2 61  ? 162.944 141.864 96.401  1.00 71.92  ? 36  VAL C CB  1 
ATOM   5708  C CG1 . VAL C 2 61  ? 162.368 140.522 96.814  1.00 65.76  ? 36  VAL C CG1 1 
ATOM   5709  C CG2 . VAL C 2 61  ? 161.973 142.982 96.739  1.00 69.37  ? 36  VAL C CG2 1 
ATOM   5710  N N   . CYS C 2 62  ? 164.481 143.729 98.879  1.00 66.04  ? 37  CYS C N   1 
ATOM   5711  C CA  . CYS C 2 62  ? 164.366 144.228 100.243 1.00 64.71  ? 37  CYS C CA  1 
ATOM   5712  C C   . CYS C 2 62  ? 162.963 144.780 100.456 1.00 58.06  ? 37  CYS C C   1 
ATOM   5713  O O   . CYS C 2 62  ? 162.527 145.676 99.725  1.00 58.67  ? 37  CYS C O   1 
ATOM   5714  C CB  . CYS C 2 62  ? 165.414 145.307 100.510 1.00 69.36  ? 37  CYS C CB  1 
ATOM   5715  S SG  . CYS C 2 62  ? 167.113 144.701 100.563 1.00 94.93  ? 37  CYS C SG  1 
ATOM   5716  N N   . VAL C 2 63  ? 162.261 144.251 101.453 1.00 54.87  ? 38  VAL C N   1 
ATOM   5717  C CA  . VAL C 2 63  ? 160.906 144.678 101.776 1.00 51.08  ? 38  VAL C CA  1 
ATOM   5718  C C   . VAL C 2 63  ? 160.930 145.361 103.135 1.00 46.99  ? 38  VAL C C   1 
ATOM   5719  O O   . VAL C 2 63  ? 161.217 144.724 104.155 1.00 43.55  ? 38  VAL C O   1 
ATOM   5720  C CB  . VAL C 2 63  ? 159.922 143.499 101.771 1.00 47.77  ? 38  VAL C CB  1 
ATOM   5721  C CG1 . VAL C 2 63  ? 158.498 144.002 101.906 1.00 45.06  ? 38  VAL C CG1 1 
ATOM   5722  C CG2 . VAL C 2 63  ? 160.079 142.685 100.498 1.00 48.73  ? 38  VAL C CG2 1 
ATOM   5723  N N   . GLY C 2 64  ? 160.626 146.655 103.147 1.00 48.59  ? 39  GLY C N   1 
ATOM   5724  C CA  . GLY C 2 64  ? 160.496 147.390 104.386 1.00 39.51  ? 39  GLY C CA  1 
ATOM   5725  C C   . GLY C 2 64  ? 159.077 147.322 104.918 1.00 34.51  ? 39  GLY C C   1 
ATOM   5726  O O   . GLY C 2 64  ? 158.112 147.313 104.160 1.00 45.65  ? 39  GLY C O   1 
ATOM   5727  N N   . MET C 2 65  ? 158.957 147.287 106.240 1.00 24.42  ? 40  MET C N   1 
ATOM   5728  C CA  . MET C 2 65  ? 157.667 147.119 106.889 1.00 26.88  ? 40  MET C CA  1 
ATOM   5729  C C   . MET C 2 65  ? 157.523 148.114 108.026 1.00 29.94  ? 40  MET C C   1 
ATOM   5730  O O   . MET C 2 65  ? 158.469 148.352 108.781 1.00 39.80  ? 40  MET C O   1 
ATOM   5731  C CB  . MET C 2 65  ? 157.490 145.693 107.420 1.00 31.02  ? 40  MET C CB  1 
ATOM   5732  C CG  . MET C 2 65  ? 157.543 144.633 106.340 1.00 35.08  ? 40  MET C CG  1 
ATOM   5733  S SD  . MET C 2 65  ? 157.370 142.958 106.965 1.00 46.22  ? 40  MET C SD  1 
ATOM   5734  C CE  . MET C 2 65  ? 157.473 142.041 105.434 1.00 43.56  ? 40  MET C CE  1 
ATOM   5735  N N   . ASN C 2 66  ? 156.330 148.688 108.140 1.00 23.69  ? 41  ASN C N   1 
ATOM   5736  C CA  . ASN C 2 66  ? 155.971 149.518 109.275 1.00 25.20  ? 41  ASN C CA  1 
ATOM   5737  C C   . ASN C 2 66  ? 154.525 149.232 109.650 1.00 27.08  ? 41  ASN C C   1 
ATOM   5738  O O   . ASN C 2 66  ? 153.700 148.909 108.793 1.00 30.12  ? 41  ASN C O   1 
ATOM   5739  C CB  . ASN C 2 66  ? 156.165 151.010 108.964 1.00 26.70  ? 41  ASN C CB  1 
ATOM   5740  C CG  . ASN C 2 66  ? 155.494 151.432 107.676 1.00 30.42  ? 41  ASN C CG  1 
ATOM   5741  O OD1 . ASN C 2 66  ? 156.024 151.217 106.587 1.00 40.40  ? 41  ASN C OD1 1 
ATOM   5742  N ND2 . ASN C 2 66  ? 154.326 152.049 107.794 1.00 30.02  ? 41  ASN C ND2 1 
ATOM   5743  N N   . ILE C 2 67  ? 154.229 149.340 110.942 1.00 30.45  ? 42  ILE C N   1 
ATOM   5744  C CA  . ILE C 2 67  ? 152.916 149.005 111.478 1.00 26.12  ? 42  ILE C CA  1 
ATOM   5745  C C   . ILE C 2 67  ? 152.381 150.195 112.258 1.00 29.75  ? 42  ILE C C   1 
ATOM   5746  O O   . ILE C 2 67  ? 153.100 150.780 113.075 1.00 38.08  ? 42  ILE C O   1 
ATOM   5747  C CB  . ILE C 2 67  ? 152.975 147.760 112.383 1.00 23.30  ? 42  ILE C CB  1 
ATOM   5748  C CG1 . ILE C 2 67  ? 153.612 146.584 111.645 1.00 23.76  ? 42  ILE C CG1 1 
ATOM   5749  C CG2 . ILE C 2 67  ? 151.592 147.392 112.878 1.00 27.91  ? 42  ILE C CG2 1 
ATOM   5750  C CD1 . ILE C 2 67  ? 153.738 145.339 112.490 1.00 31.57  ? 42  ILE C CD1 1 
ATOM   5751  N N   . ASP C 2 68  ? 151.123 150.552 112.009 1.00 24.09  ? 43  ASP C N   1 
ATOM   5752  C CA  . ASP C 2 68  ? 150.412 151.546 112.807 1.00 26.74  ? 43  ASP C CA  1 
ATOM   5753  C C   . ASP C 2 68  ? 149.350 150.804 113.609 1.00 26.13  ? 43  ASP C C   1 
ATOM   5754  O O   . ASP C 2 68  ? 148.330 150.380 113.057 1.00 32.67  ? 43  ASP C O   1 
ATOM   5755  C CB  . ASP C 2 68  ? 149.793 152.627 111.925 1.00 34.90  ? 43  ASP C CB  1 
ATOM   5756  C CG  . ASP C 2 68  ? 150.832 153.403 111.141 1.00 44.29  ? 43  ASP C CG  1 
ATOM   5757  O OD1 . ASP C 2 68  ? 151.924 153.656 111.692 1.00 45.94  ? 43  ASP C OD1 1 
ATOM   5758  O OD2 . ASP C 2 68  ? 150.557 153.763 109.978 1.00 48.35  ? 43  ASP C OD2 1 
ATOM   5759  N N   . ILE C 2 69  ? 149.588 150.652 114.905 1.00 24.00  ? 44  ILE C N   1 
ATOM   5760  C CA  . ILE C 2 69  ? 148.716 149.851 115.757 1.00 25.75  ? 44  ILE C CA  1 
ATOM   5761  C C   . ILE C 2 69  ? 147.450 150.634 116.074 1.00 29.76  ? 44  ILE C C   1 
ATOM   5762  O O   . ILE C 2 69  ? 147.510 151.774 116.547 1.00 36.65  ? 44  ILE C O   1 
ATOM   5763  C CB  . ILE C 2 69  ? 149.455 149.428 117.033 1.00 27.28  ? 44  ILE C CB  1 
ATOM   5764  C CG1 . ILE C 2 69  ? 150.647 148.546 116.659 1.00 26.06  ? 44  ILE C CG1 1 
ATOM   5765  C CG2 . ILE C 2 69  ? 148.519 148.700 117.978 1.00 24.60  ? 44  ILE C CG2 1 
ATOM   5766  C CD1 . ILE C 2 69  ? 151.587 148.283 117.792 1.00 31.69  ? 44  ILE C CD1 1 
ATOM   5767  N N   . ALA C 2 70  ? 146.296 150.019 115.815 1.00 28.94  ? 45  ALA C N   1 
ATOM   5768  C CA  . ALA C 2 70  ? 145.007 150.625 116.124 1.00 26.07  ? 45  ALA C CA  1 
ATOM   5769  C C   . ALA C 2 70  ? 144.552 150.329 117.550 1.00 25.44  ? 45  ALA C C   1 
ATOM   5770  O O   . ALA C 2 70  ? 144.188 151.250 118.287 1.00 30.23  ? 45  ALA C O   1 
ATOM   5771  C CB  . ALA C 2 70  ? 143.949 150.148 115.125 1.00 21.73  ? 45  ALA C CB  1 
ATOM   5772  N N   . SER C 2 71  ? 144.578 149.062 117.956 1.00 23.68  ? 46  SER C N   1 
ATOM   5773  C CA  . SER C 2 71  ? 144.115 148.674 119.282 1.00 27.24  ? 46  SER C CA  1 
ATOM   5774  C C   . SER C 2 71  ? 144.539 147.239 119.556 1.00 30.22  ? 46  SER C C   1 
ATOM   5775  O O   . SER C 2 71  ? 144.809 146.465 118.633 1.00 29.28  ? 46  SER C O   1 
ATOM   5776  C CB  . SER C 2 71  ? 142.595 148.810 119.415 1.00 30.96  ? 46  SER C CB  1 
ATOM   5777  O OG  . SER C 2 71  ? 141.926 147.925 118.536 1.00 29.87  ? 46  SER C OG  1 
ATOM   5778  N N   . ILE C 2 72  ? 144.589 146.898 120.839 1.00 36.38  ? 47  ILE C N   1 
ATOM   5779  C CA  . ILE C 2 72  ? 144.644 145.516 121.301 1.00 37.82  ? 47  ILE C CA  1 
ATOM   5780  C C   . ILE C 2 72  ? 143.308 145.232 121.976 1.00 42.04  ? 47  ILE C C   1 
ATOM   5781  O O   . ILE C 2 72  ? 143.111 145.547 123.154 1.00 40.15  ? 47  ILE C O   1 
ATOM   5782  C CB  . ILE C 2 72  ? 145.823 145.266 122.248 1.00 36.21  ? 47  ILE C CB  1 
ATOM   5783  C CG1 . ILE C 2 72  ? 147.147 145.486 121.517 1.00 36.62  ? 47  ILE C CG1 1 
ATOM   5784  C CG2 . ILE C 2 72  ? 145.771 143.856 122.804 1.00 38.84  ? 47  ILE C CG2 1 
ATOM   5785  C CD1 . ILE C 2 72  ? 148.360 145.356 122.406 1.00 45.34  ? 47  ILE C CD1 1 
ATOM   5786  N N   . ASP C 2 73  ? 142.373 144.661 121.213 1.00 42.88  ? 48  ASP C N   1 
ATOM   5787  C CA  . ASP C 2 73  ? 140.995 144.543 121.678 1.00 43.90  ? 48  ASP C CA  1 
ATOM   5788  C C   . ASP C 2 73  ? 140.884 143.661 122.917 1.00 43.52  ? 48  ASP C C   1 
ATOM   5789  O O   . ASP C 2 73  ? 140.188 144.013 123.875 1.00 51.06  ? 48  ASP C O   1 
ATOM   5790  C CB  . ASP C 2 73  ? 140.116 143.995 120.553 1.00 46.88  ? 48  ASP C CB  1 
ATOM   5791  C CG  . ASP C 2 73  ? 140.111 144.891 119.330 1.00 53.60  ? 48  ASP C CG  1 
ATOM   5792  O OD1 . ASP C 2 73  ? 139.966 146.121 119.490 1.00 50.55  ? 48  ASP C OD1 1 
ATOM   5793  O OD2 . ASP C 2 73  ? 140.253 144.365 118.207 1.00 53.55  ? 48  ASP C OD2 1 
ATOM   5794  N N   . MET C 2 74  ? 141.563 142.516 122.922 1.00 39.19  ? 49  MET C N   1 
ATOM   5795  C CA  . MET C 2 74  ? 141.412 141.541 123.992 1.00 39.65  ? 49  MET C CA  1 
ATOM   5796  C C   . MET C 2 74  ? 142.763 140.938 124.341 1.00 40.63  ? 49  MET C C   1 
ATOM   5797  O O   . MET C 2 74  ? 143.672 140.894 123.509 1.00 49.78  ? 49  MET C O   1 
ATOM   5798  C CB  . MET C 2 74  ? 140.441 140.417 123.603 1.00 42.74  ? 49  MET C CB  1 
ATOM   5799  C CG  . MET C 2 74  ? 139.015 140.872 123.344 1.00 50.43  ? 49  MET C CG  1 
ATOM   5800  S SD  . MET C 2 74  ? 137.961 139.541 122.735 1.00 83.34  ? 49  MET C SD  1 
ATOM   5801  C CE  . MET C 2 74  ? 138.042 138.391 124.107 1.00 65.70  ? 49  MET C CE  1 
ATOM   5802  N N   . VAL C 2 75  ? 142.880 140.467 125.583 1.00 38.32  ? 50  VAL C N   1 
ATOM   5803  C CA  . VAL C 2 75  ? 144.010 139.658 126.036 1.00 37.42  ? 50  VAL C CA  1 
ATOM   5804  C C   . VAL C 2 75  ? 143.442 138.582 126.952 1.00 37.37  ? 50  VAL C C   1 
ATOM   5805  O O   . VAL C 2 75  ? 143.054 138.875 128.088 1.00 41.98  ? 50  VAL C O   1 
ATOM   5806  C CB  . VAL C 2 75  ? 145.076 140.479 126.781 1.00 38.92  ? 50  VAL C CB  1 
ATOM   5807  C CG1 . VAL C 2 75  ? 146.259 139.600 127.139 1.00 37.76  ? 50  VAL C CG1 1 
ATOM   5808  C CG2 . VAL C 2 75  ? 145.539 141.670 125.955 1.00 31.13  ? 50  VAL C CG2 1 
ATOM   5809  N N   . SER C 2 76  ? 143.395 137.344 126.469 1.00 37.52  ? 51  SER C N   1 
ATOM   5810  C CA  . SER C 2 76  ? 142.745 136.250 127.178 1.00 38.19  ? 51  SER C CA  1 
ATOM   5811  C C   . SER C 2 76  ? 143.791 135.272 127.693 1.00 43.29  ? 51  SER C C   1 
ATOM   5812  O O   . SER C 2 76  ? 144.620 134.779 126.921 1.00 44.60  ? 51  SER C O   1 
ATOM   5813  C CB  . SER C 2 76  ? 141.751 135.525 126.270 1.00 39.99  ? 51  SER C CB  1 
ATOM   5814  O OG  . SER C 2 76  ? 142.418 134.623 125.404 1.00 44.42  ? 51  SER C OG  1 
ATOM   5815  N N   . GLU C 2 77  ? 143.741 134.988 128.996 1.00 43.61  ? 52  GLU C N   1 
ATOM   5816  C CA  . GLU C 2 77  ? 144.632 134.001 129.594 1.00 43.57  ? 52  GLU C CA  1 
ATOM   5817  C C   . GLU C 2 77  ? 144.193 132.569 129.314 1.00 46.01  ? 52  GLU C C   1 
ATOM   5818  O O   . GLU C 2 77  ? 145.041 131.674 129.225 1.00 49.44  ? 52  GLU C O   1 
ATOM   5819  C CB  . GLU C 2 77  ? 144.741 134.227 131.104 1.00 41.94  ? 52  GLU C CB  1 
ATOM   5820  C CG  . GLU C 2 77  ? 145.338 135.571 131.520 1.00 44.72  ? 52  GLU C CG  1 
ATOM   5821  C CD  . GLU C 2 77  ? 144.378 136.735 131.359 1.00 44.26  ? 52  GLU C CD  1 
ATOM   5822  O OE1 . GLU C 2 77  ? 143.170 136.490 131.160 1.00 43.64  ? 52  GLU C OE1 1 
ATOM   5823  O OE2 . GLU C 2 77  ? 144.832 137.896 131.432 1.00 41.34  ? 52  GLU C OE2 1 
ATOM   5824  N N   . VAL C 2 78  ? 142.886 132.332 129.185 1.00 46.53  ? 53  VAL C N   1 
ATOM   5825  C CA  . VAL C 2 78  ? 142.378 130.980 128.953 1.00 46.63  ? 53  VAL C CA  1 
ATOM   5826  C C   . VAL C 2 78  ? 142.892 130.430 127.629 1.00 43.32  ? 53  VAL C C   1 
ATOM   5827  O O   . VAL C 2 78  ? 143.428 129.318 127.562 1.00 38.08  ? 53  VAL C O   1 
ATOM   5828  C CB  . VAL C 2 78  ? 140.840 130.969 129.004 1.00 49.76  ? 53  VAL C CB  1 
ATOM   5829  C CG1 . VAL C 2 78  ? 140.310 129.587 128.660 1.00 52.23  ? 53  VAL C CG1 1 
ATOM   5830  C CG2 . VAL C 2 78  ? 140.354 131.404 130.371 1.00 47.02  ? 53  VAL C CG2 1 
ATOM   5831  N N   . ASN C 2 79  ? 142.741 131.204 126.558 1.00 41.85  ? 54  ASN C N   1 
ATOM   5832  C CA  . ASN C 2 79  ? 143.241 130.813 125.248 1.00 45.16  ? 54  ASN C CA  1 
ATOM   5833  C C   . ASN C 2 79  ? 144.707 131.165 125.045 1.00 49.70  ? 54  ASN C C   1 
ATOM   5834  O O   . ASN C 2 79  ? 145.316 130.663 124.094 1.00 46.50  ? 54  ASN C O   1 
ATOM   5835  C CB  . ASN C 2 79  ? 142.405 131.473 124.150 1.00 45.35  ? 54  ASN C CB  1 
ATOM   5836  C CG  . ASN C 2 79  ? 140.925 131.206 124.309 1.00 47.65  ? 54  ASN C CG  1 
ATOM   5837  O OD1 . ASN C 2 79  ? 140.511 130.075 124.558 1.00 49.67  ? 54  ASN C OD1 1 
ATOM   5838  N ND2 . ASN C 2 79  ? 140.118 132.251 124.176 1.00 47.01  ? 54  ASN C ND2 1 
ATOM   5839  N N   . MET C 2 80  ? 145.280 132.004 125.910 1.00 48.62  ? 55  MET C N   1 
ATOM   5840  C CA  . MET C 2 80  ? 146.669 132.441 125.796 1.00 45.15  ? 55  MET C CA  1 
ATOM   5841  C C   . MET C 2 80  ? 146.912 133.070 124.424 1.00 44.61  ? 55  MET C C   1 
ATOM   5842  O O   . MET C 2 80  ? 147.686 132.575 123.603 1.00 45.91  ? 55  MET C O   1 
ATOM   5843  C CB  . MET C 2 80  ? 147.632 131.278 126.053 1.00 45.45  ? 55  MET C CB  1 
ATOM   5844  C CG  . MET C 2 80  ? 147.790 130.914 127.516 1.00 50.00  ? 55  MET C CG  1 
ATOM   5845  S SD  . MET C 2 80  ? 149.035 129.639 127.771 1.00 67.50  ? 55  MET C SD  1 
ATOM   5846  C CE  . MET C 2 80  ? 149.125 129.608 129.558 1.00 63.89  ? 55  MET C CE  1 
ATOM   5847  N N   . ASP C 2 81  ? 146.222 134.183 124.196 1.00 37.20  ? 56  ASP C N   1 
ATOM   5848  C CA  . ASP C 2 81  ? 146.374 134.951 122.972 1.00 35.78  ? 56  ASP C CA  1 
ATOM   5849  C C   . ASP C 2 81  ? 145.777 136.333 123.185 1.00 36.46  ? 56  ASP C C   1 
ATOM   5850  O O   . ASP C 2 81  ? 145.076 136.585 124.167 1.00 40.82  ? 56  ASP C O   1 
ATOM   5851  C CB  . ASP C 2 81  ? 145.708 134.243 121.786 1.00 36.87  ? 56  ASP C CB  1 
ATOM   5852  C CG  . ASP C 2 81  ? 144.274 133.835 122.076 1.00 41.89  ? 56  ASP C CG  1 
ATOM   5853  O OD1 . ASP C 2 81  ? 143.695 134.317 123.071 1.00 45.98  ? 56  ASP C OD1 1 
ATOM   5854  O OD2 . ASP C 2 81  ? 143.720 133.025 121.304 1.00 41.44  ? 56  ASP C OD2 1 
ATOM   5855  N N   . TYR C 2 82  ? 146.072 137.227 122.250 1.00 34.46  ? 57  TYR C N   1 
ATOM   5856  C CA  . TYR C 2 82  ? 145.566 138.589 122.280 1.00 34.78  ? 57  TYR C CA  1 
ATOM   5857  C C   . TYR C 2 82  ? 145.071 138.940 120.887 1.00 31.62  ? 57  TYR C C   1 
ATOM   5858  O O   . TYR C 2 82  ? 145.554 138.400 119.889 1.00 31.16  ? 57  TYR C O   1 
ATOM   5859  C CB  . TYR C 2 82  ? 146.631 139.603 122.729 1.00 33.76  ? 57  TYR C CB  1 
ATOM   5860  C CG  . TYR C 2 82  ? 147.834 139.693 121.818 1.00 33.34  ? 57  TYR C CG  1 
ATOM   5861  C CD1 . TYR C 2 82  ? 148.793 138.692 121.795 1.00 35.73  ? 57  TYR C CD1 1 
ATOM   5862  C CD2 . TYR C 2 82  ? 148.009 140.785 120.982 1.00 35.70  ? 57  TYR C CD2 1 
ATOM   5863  C CE1 . TYR C 2 82  ? 149.889 138.776 120.961 1.00 33.91  ? 57  TYR C CE1 1 
ATOM   5864  C CE2 . TYR C 2 82  ? 149.101 140.877 120.147 1.00 37.47  ? 57  TYR C CE2 1 
ATOM   5865  C CZ  . TYR C 2 82  ? 150.038 139.870 120.140 1.00 37.25  ? 57  TYR C CZ  1 
ATOM   5866  O OH  . TYR C 2 82  ? 151.130 139.958 119.310 1.00 35.20  ? 57  TYR C OH  1 
ATOM   5867  N N   . THR C 2 83  ? 144.105 139.848 120.822 1.00 32.39  ? 58  THR C N   1 
ATOM   5868  C CA  . THR C 2 83  ? 143.557 140.296 119.551 1.00 28.62  ? 58  THR C CA  1 
ATOM   5869  C C   . THR C 2 83  ? 144.106 141.679 119.239 1.00 28.78  ? 58  THR C C   1 
ATOM   5870  O O   . THR C 2 83  ? 144.046 142.582 120.078 1.00 32.46  ? 58  THR C O   1 
ATOM   5871  C CB  . THR C 2 83  ? 142.029 140.324 119.587 1.00 33.56  ? 58  THR C CB  1 
ATOM   5872  O OG1 . THR C 2 83  ? 141.532 139.005 119.842 1.00 32.66  ? 58  THR C OG1 1 
ATOM   5873  C CG2 . THR C 2 83  ? 141.477 140.814 118.262 1.00 33.44  ? 58  THR C CG2 1 
ATOM   5874  N N   . LEU C 2 84  ? 144.634 141.837 118.031 1.00 24.37  ? 59  LEU C N   1 
ATOM   5875  C CA  . LEU C 2 84  ? 145.338 143.043 117.625 1.00 24.18  ? 59  LEU C CA  1 
ATOM   5876  C C   . LEU C 2 84  ? 144.729 143.567 116.337 1.00 23.76  ? 59  LEU C C   1 
ATOM   5877  O O   . LEU C 2 84  ? 144.527 142.802 115.389 1.00 25.52  ? 59  LEU C O   1 
ATOM   5878  C CB  . LEU C 2 84  ? 146.830 142.759 117.426 1.00 21.29  ? 59  LEU C CB  1 
ATOM   5879  C CG  . LEU C 2 84  ? 147.714 143.907 116.941 1.00 25.25  ? 59  LEU C CG  1 
ATOM   5880  C CD1 . LEU C 2 84  ? 147.952 144.913 118.046 1.00 37.43  ? 59  LEU C CD1 1 
ATOM   5881  C CD2 . LEU C 2 84  ? 149.030 143.368 116.418 1.00 21.57  ? 59  LEU C CD2 1 
ATOM   5882  N N   . THR C 2 85  ? 144.450 144.865 116.298 1.00 21.01  ? 60  THR C N   1 
ATOM   5883  C CA  . THR C 2 85  ? 144.050 145.543 115.075 1.00 18.63  ? 60  THR C CA  1 
ATOM   5884  C C   . THR C 2 85  ? 145.153 146.517 114.695 1.00 19.09  ? 60  THR C C   1 
ATOM   5885  O O   . THR C 2 85  ? 145.649 147.261 115.547 1.00 24.45  ? 60  THR C O   1 
ATOM   5886  C CB  . THR C 2 85  ? 142.723 146.281 115.257 1.00 26.08  ? 60  THR C CB  1 
ATOM   5887  O OG1 . THR C 2 85  ? 141.736 145.373 115.761 1.00 27.62  ? 60  THR C OG1 1 
ATOM   5888  C CG2 . THR C 2 85  ? 142.245 146.847 113.930 1.00 22.89  ? 60  THR C CG2 1 
ATOM   5889  N N   . MET C 2 86  ? 145.537 146.508 113.423 1.00 19.03  ? 61  MET C N   1 
ATOM   5890  C CA  . MET C 2 86  ? 146.666 147.309 112.983 1.00 17.35  ? 61  MET C CA  1 
ATOM   5891  C C   . MET C 2 86  ? 146.534 147.624 111.504 1.00 16.28  ? 61  MET C C   1 
ATOM   5892  O O   . MET C 2 86  ? 145.755 147.000 110.780 1.00 19.51  ? 61  MET C O   1 
ATOM   5893  C CB  . MET C 2 86  ? 147.987 146.584 113.246 1.00 17.88  ? 61  MET C CB  1 
ATOM   5894  C CG  . MET C 2 86  ? 148.103 145.272 112.496 1.00 20.31  ? 61  MET C CG  1 
ATOM   5895  S SD  . MET C 2 86  ? 149.640 144.399 112.821 1.00 39.97  ? 61  MET C SD  1 
ATOM   5896  C CE  . MET C 2 86  ? 149.365 142.907 111.880 1.00 22.35  ? 61  MET C CE  1 
ATOM   5897  N N   . TYR C 2 87  ? 147.319 148.601 111.066 1.00 15.63  ? 62  TYR C N   1 
ATOM   5898  C CA  . TYR C 2 87  ? 147.562 148.851 109.651 1.00 17.41  ? 62  TYR C CA  1 
ATOM   5899  C C   . TYR C 2 87  ? 148.946 148.300 109.336 1.00 20.83  ? 62  TYR C C   1 
ATOM   5900  O O   . TYR C 2 87  ? 149.955 148.820 109.820 1.00 27.07  ? 62  TYR C O   1 
ATOM   5901  C CB  . TYR C 2 87  ? 147.463 150.337 109.311 1.00 18.22  ? 62  TYR C CB  1 
ATOM   5902  C CG  . TYR C 2 87  ? 146.163 150.992 109.727 1.00 22.09  ? 62  TYR C CG  1 
ATOM   5903  C CD1 . TYR C 2 87  ? 145.928 151.349 111.048 1.00 23.49  ? 62  TYR C CD1 1 
ATOM   5904  C CD2 . TYR C 2 87  ? 145.171 151.256 108.792 1.00 22.77  ? 62  TYR C CD2 1 
ATOM   5905  C CE1 . TYR C 2 87  ? 144.741 151.944 111.426 1.00 24.37  ? 62  TYR C CE1 1 
ATOM   5906  C CE2 . TYR C 2 87  ? 143.982 151.852 109.161 1.00 24.81  ? 62  TYR C CE2 1 
ATOM   5907  C CZ  . TYR C 2 87  ? 143.773 152.194 110.478 1.00 25.14  ? 62  TYR C CZ  1 
ATOM   5908  O OH  . TYR C 2 87  ? 142.591 152.790 110.849 1.00 25.59  ? 62  TYR C OH  1 
ATOM   5909  N N   . PHE C 2 88  ? 148.990 147.253 108.520 1.00 16.33  ? 63  PHE C N   1 
ATOM   5910  C CA  . PHE C 2 88  ? 150.227 146.557 108.198 1.00 15.62  ? 63  PHE C CA  1 
ATOM   5911  C C   . PHE C 2 88  ? 150.694 147.001 106.822 1.00 17.03  ? 63  PHE C C   1 
ATOM   5912  O O   . PHE C 2 88  ? 150.005 146.772 105.822 1.00 21.79  ? 63  PHE C O   1 
ATOM   5913  C CB  . PHE C 2 88  ? 150.016 145.043 108.233 1.00 15.11  ? 63  PHE C CB  1 
ATOM   5914  C CG  . PHE C 2 88  ? 151.241 144.248 107.888 1.00 19.24  ? 63  PHE C CG  1 
ATOM   5915  C CD1 . PHE C 2 88  ? 152.300 144.161 108.773 1.00 22.49  ? 63  PHE C CD1 1 
ATOM   5916  C CD2 . PHE C 2 88  ? 151.328 143.582 106.679 1.00 20.58  ? 63  PHE C CD2 1 
ATOM   5917  C CE1 . PHE C 2 88  ? 153.425 143.430 108.454 1.00 22.89  ? 63  PHE C CE1 1 
ATOM   5918  C CE2 . PHE C 2 88  ? 152.449 142.848 106.356 1.00 23.39  ? 63  PHE C CE2 1 
ATOM   5919  C CZ  . PHE C 2 88  ? 153.499 142.772 107.244 1.00 24.68  ? 63  PHE C CZ  1 
ATOM   5920  N N   . GLN C 2 89  ? 151.862 147.633 106.775 1.00 16.56  ? 64  GLN C N   1 
ATOM   5921  C CA  . GLN C 2 89  ? 152.379 148.235 105.559 1.00 18.67  ? 64  GLN C CA  1 
ATOM   5922  C C   . GLN C 2 89  ? 153.653 147.524 105.132 1.00 22.39  ? 64  GLN C C   1 
ATOM   5923  O O   . GLN C 2 89  ? 154.513 147.218 105.962 1.00 25.56  ? 64  GLN C O   1 
ATOM   5924  C CB  . GLN C 2 89  ? 152.656 149.723 105.768 1.00 19.48  ? 64  GLN C CB  1 
ATOM   5925  C CG  . GLN C 2 89  ? 151.428 150.525 106.154 1.00 21.10  ? 64  GLN C CG  1 
ATOM   5926  C CD  . GLN C 2 89  ? 151.594 152.004 105.894 1.00 34.01  ? 64  GLN C CD  1 
ATOM   5927  O OE1 . GLN C 2 89  ? 152.662 152.458 105.485 1.00 29.58  ? 64  GLN C OE1 1 
ATOM   5928  N NE2 . GLN C 2 89  ? 150.536 152.769 106.134 1.00 46.15  ? 64  GLN C NE2 1 
ATOM   5929  N N   . GLN C 2 90  ? 153.763 147.266 103.835 1.00 25.70  ? 65  GLN C N   1 
ATOM   5930  C CA  . GLN C 2 90  ? 154.943 146.662 103.240 1.00 28.75  ? 65  GLN C CA  1 
ATOM   5931  C C   . GLN C 2 90  ? 155.456 147.576 102.141 1.00 32.88  ? 65  GLN C C   1 
ATOM   5932  O O   . GLN C 2 90  ? 154.669 148.140 101.375 1.00 42.56  ? 65  GLN C O   1 
ATOM   5933  C CB  . GLN C 2 90  ? 154.637 145.278 102.668 1.00 31.18  ? 65  GLN C CB  1 
ATOM   5934  C CG  . GLN C 2 90  ? 154.326 144.234 103.716 1.00 34.94  ? 65  GLN C CG  1 
ATOM   5935  C CD  . GLN C 2 90  ? 153.893 142.919 103.110 1.00 44.98  ? 65  GLN C CD  1 
ATOM   5936  O OE1 . GLN C 2 90  ? 154.667 141.965 103.055 1.00 48.81  ? 65  GLN C OE1 1 
ATOM   5937  N NE2 . GLN C 2 90  ? 152.653 142.863 102.641 1.00 37.18  ? 65  GLN C NE2 1 
ATOM   5938  N N   . TYR C 2 91  ? 156.773 147.727 102.066 1.00 32.57  ? 66  TYR C N   1 
ATOM   5939  C CA  . TYR C 2 91  ? 157.376 148.723 101.193 1.00 36.34  ? 66  TYR C CA  1 
ATOM   5940  C C   . TYR C 2 91  ? 158.585 148.088 100.527 1.00 42.77  ? 66  TYR C C   1 
ATOM   5941  O O   . TYR C 2 91  ? 159.524 147.674 101.212 1.00 51.69  ? 66  TYR C O   1 
ATOM   5942  C CB  . TYR C 2 91  ? 157.766 149.968 102.001 1.00 42.10  ? 66  TYR C CB  1 
ATOM   5943  C CG  . TYR C 2 91  ? 158.560 151.028 101.268 1.00 54.77  ? 66  TYR C CG  1 
ATOM   5944  C CD1 . TYR C 2 91  ? 159.926 150.891 101.051 1.00 60.52  ? 66  TYR C CD1 1 
ATOM   5945  C CD2 . TYR C 2 91  ? 157.945 152.194 100.834 1.00 54.54  ? 66  TYR C CD2 1 
ATOM   5946  C CE1 . TYR C 2 91  ? 160.646 151.868 100.395 1.00 64.09  ? 66  TYR C CE1 1 
ATOM   5947  C CE2 . TYR C 2 91  ? 158.657 153.177 100.184 1.00 60.08  ? 66  TYR C CE2 1 
ATOM   5948  C CZ  . TYR C 2 91  ? 160.006 153.009 99.963  1.00 66.49  ? 66  TYR C CZ  1 
ATOM   5949  O OH  . TYR C 2 91  ? 160.717 153.989 99.309  1.00 66.95  ? 66  TYR C OH  1 
ATOM   5950  N N   . TRP C 2 92  ? 158.559 148.006 99.200  1.00 42.69  ? 67  TRP C N   1 
ATOM   5951  C CA  . TRP C 2 92  ? 159.651 147.417 98.440  1.00 41.54  ? 67  TRP C CA  1 
ATOM   5952  C C   . TRP C 2 92  ? 159.724 148.101 97.083  1.00 45.89  ? 67  TRP C C   1 
ATOM   5953  O O   . TRP C 2 92  ? 158.906 148.965 96.756  1.00 52.96  ? 67  TRP C O   1 
ATOM   5954  C CB  . TRP C 2 92  ? 159.474 145.902 98.298  1.00 42.89  ? 67  TRP C CB  1 
ATOM   5955  C CG  . TRP C 2 92  ? 158.359 145.504 97.377  1.00 46.04  ? 67  TRP C CG  1 
ATOM   5956  C CD1 . TRP C 2 92  ? 158.453 145.239 96.043  1.00 45.84  ? 67  TRP C CD1 1 
ATOM   5957  C CD2 . TRP C 2 92  ? 156.988 145.286 97.733  1.00 47.04  ? 67  TRP C CD2 1 
ATOM   5958  N NE1 . TRP C 2 92  ? 157.222 144.893 95.541  1.00 43.72  ? 67  TRP C NE1 1 
ATOM   5959  C CE2 . TRP C 2 92  ? 156.306 144.913 96.559  1.00 38.86  ? 67  TRP C CE2 1 
ATOM   5960  C CE3 . TRP C 2 92  ? 156.270 145.381 98.928  1.00 42.50  ? 67  TRP C CE3 1 
ATOM   5961  C CZ2 . TRP C 2 92  ? 154.943 144.634 96.546  1.00 33.30  ? 67  TRP C CZ2 1 
ATOM   5962  C CZ3 . TRP C 2 92  ? 154.916 145.104 98.912  1.00 38.16  ? 67  TRP C CZ3 1 
ATOM   5963  C CH2 . TRP C 2 92  ? 154.267 144.736 97.730  1.00 33.75  ? 67  TRP C CH2 1 
ATOM   5964  N N   . ARG C 2 93  ? 160.714 147.708 96.287  1.00 48.76  ? 68  ARG C N   1 
ATOM   5965  C CA  . ARG C 2 93  ? 160.950 148.304 94.980  1.00 59.81  ? 68  ARG C CA  1 
ATOM   5966  C C   . ARG C 2 93  ? 160.816 147.234 93.907  1.00 62.22  ? 68  ARG C C   1 
ATOM   5967  O O   . ARG C 2 93  ? 161.442 146.174 94.001  1.00 62.31  ? 68  ARG C O   1 
ATOM   5968  C CB  . ARG C 2 93  ? 162.332 148.958 94.918  1.00 68.84  ? 68  ARG C CB  1 
ATOM   5969  C CG  . ARG C 2 93  ? 162.580 149.783 93.666  1.00 72.93  ? 68  ARG C CG  1 
ATOM   5970  C CD  . ARG C 2 93  ? 163.858 150.593 93.798  1.00 78.66  ? 68  ARG C CD  1 
ATOM   5971  N NE  . ARG C 2 93  ? 164.088 151.450 92.642  1.00 92.05  ? 68  ARG C NE  1 
ATOM   5972  C CZ  . ARG C 2 93  ? 164.760 151.084 91.559  1.00 96.93  ? 68  ARG C CZ  1 
ATOM   5973  N NH1 . ARG C 2 93  ? 165.284 149.874 91.447  1.00 94.61  ? 68  ARG C NH1 1 
ATOM   5974  N NH2 . ARG C 2 93  ? 164.912 151.953 90.564  1.00 97.25  ? 68  ARG C NH2 1 
ATOM   5975  N N   . ASP C 2 94  ? 160.002 147.517 92.892  1.00 64.99  ? 69  ASP C N   1 
ATOM   5976  C CA  . ASP C 2 94  ? 159.808 146.624 91.753  1.00 72.24  ? 69  ASP C CA  1 
ATOM   5977  C C   . ASP C 2 94  ? 160.040 147.428 90.482  1.00 78.17  ? 69  ASP C C   1 
ATOM   5978  O O   . ASP C 2 94  ? 159.239 148.307 90.150  1.00 80.50  ? 69  ASP C O   1 
ATOM   5979  C CB  . ASP C 2 94  ? 158.410 146.004 91.767  1.00 71.30  ? 69  ASP C CB  1 
ATOM   5980  C CG  . ASP C 2 94  ? 158.283 144.828 90.815  1.00 75.71  ? 69  ASP C CG  1 
ATOM   5981  O OD1 . ASP C 2 94  ? 159.231 144.575 90.043  1.00 81.63  ? 69  ASP C OD1 1 
ATOM   5982  O OD2 . ASP C 2 94  ? 157.233 144.153 90.842  1.00 70.50  ? 69  ASP C OD2 1 
ATOM   5983  N N   . LYS C 2 95  ? 161.129 147.129 89.769  1.00 79.10  ? 70  LYS C N   1 
ATOM   5984  C CA  . LYS C 2 95  ? 161.445 147.892 88.565  1.00 85.50  ? 70  LYS C CA  1 
ATOM   5985  C C   . LYS C 2 95  ? 160.395 147.698 87.479  1.00 88.42  ? 70  LYS C C   1 
ATOM   5986  O O   . LYS C 2 95  ? 160.188 148.593 86.652  1.00 92.19  ? 70  LYS C O   1 
ATOM   5987  C CB  . LYS C 2 95  ? 162.823 147.497 88.031  1.00 86.93  ? 70  LYS C CB  1 
ATOM   5988  C CG  . LYS C 2 95  ? 163.967 147.713 89.004  1.00 91.03  ? 70  LYS C CG  1 
ATOM   5989  C CD  . LYS C 2 95  ? 165.232 147.031 88.507  1.00 94.51  ? 70  LYS C CD  1 
ATOM   5990  C CE  . LYS C 2 95  ? 166.342 147.091 89.541  1.00 90.74  ? 70  LYS C CE  1 
ATOM   5991  N NZ  . LYS C 2 95  ? 167.518 146.276 89.128  1.00 83.22  ? 70  LYS C NZ  1 
ATOM   5992  N N   . ARG C 2 96  ? 159.723 146.545 87.462  1.00 81.41  ? 71  ARG C N   1 
ATOM   5993  C CA  . ARG C 2 96  ? 158.713 146.275 86.447  1.00 83.08  ? 71  ARG C CA  1 
ATOM   5994  C C   . ARG C 2 96  ? 157.504 147.197 86.549  1.00 79.64  ? 71  ARG C C   1 
ATOM   5995  O O   . ARG C 2 96  ? 156.714 147.257 85.601  1.00 72.69  ? 71  ARG C O   1 
ATOM   5996  C CB  . ARG C 2 96  ? 158.249 144.823 86.546  1.00 76.54  ? 71  ARG C CB  1 
ATOM   5997  C CG  . ARG C 2 96  ? 159.361 143.801 86.415  1.00 71.68  ? 71  ARG C CG  1 
ATOM   5998  C CD  . ARG C 2 96  ? 158.837 142.407 86.705  1.00 72.39  ? 71  ARG C CD  1 
ATOM   5999  N NE  . ARG C 2 96  ? 158.296 142.307 88.055  1.00 69.10  ? 71  ARG C NE  1 
ATOM   6000  C CZ  . ARG C 2 96  ? 157.890 141.178 88.618  1.00 67.99  ? 71  ARG C CZ  1 
ATOM   6001  N NH1 . ARG C 2 96  ? 157.968 140.022 87.982  1.00 65.94  ? 71  ARG C NH1 1 
ATOM   6002  N NH2 . ARG C 2 96  ? 157.399 141.210 89.854  1.00 65.20  ? 71  ARG C NH2 1 
ATOM   6003  N N   . LEU C 2 97  ? 157.340 147.908 87.665  1.00 78.71  ? 72  LEU C N   1 
ATOM   6004  C CA  . LEU C 2 97  ? 156.205 148.795 87.880  1.00 82.27  ? 72  LEU C CA  1 
ATOM   6005  C C   . LEU C 2 97  ? 156.585 150.269 87.787  1.00 84.79  ? 72  LEU C C   1 
ATOM   6006  O O   . LEU C 2 97  ? 155.819 151.131 88.229  1.00 87.97  ? 72  LEU C O   1 
ATOM   6007  C CB  . LEU C 2 97  ? 155.548 148.499 89.229  1.00 83.00  ? 72  LEU C CB  1 
ATOM   6008  C CG  . LEU C 2 97  ? 154.975 147.090 89.376  1.00 79.22  ? 72  LEU C CG  1 
ATOM   6009  C CD1 . LEU C 2 97  ? 154.461 146.860 90.786  1.00 72.64  ? 72  LEU C CD1 1 
ATOM   6010  C CD2 . LEU C 2 97  ? 153.868 146.866 88.361  1.00 76.53  ? 72  LEU C CD2 1 
ATOM   6011  N N   . ALA C 2 98  ? 157.751 150.580 87.230  1.00 84.49  ? 73  ALA C N   1 
ATOM   6012  C CA  . ALA C 2 98  ? 158.147 151.972 87.075  1.00 87.12  ? 73  ALA C CA  1 
ATOM   6013  C C   . ALA C 2 98  ? 157.330 152.631 85.971  1.00 90.27  ? 73  ALA C C   1 
ATOM   6014  O O   . ALA C 2 98  ? 157.185 152.079 84.876  1.00 85.92  ? 73  ALA C O   1 
ATOM   6015  C CB  . ALA C 2 98  ? 159.638 152.068 86.761  1.00 85.10  ? 73  ALA C CB  1 
ATOM   6016  N N   . TYR C 2 99  ? 156.800 153.818 86.259  1.00 90.55  ? 74  TYR C N   1 
ATOM   6017  C CA  . TYR C 2 99  ? 156.015 154.578 85.300  1.00 89.04  ? 74  TYR C CA  1 
ATOM   6018  C C   . TYR C 2 99  ? 156.511 156.015 85.246  1.00 95.17  ? 74  TYR C C   1 
ATOM   6019  O O   . TYR C 2 99  ? 156.933 156.584 86.256  1.00 94.84  ? 74  TYR C O   1 
ATOM   6020  C CB  . TYR C 2 99  ? 154.513 154.537 85.645  1.00 88.73  ? 74  TYR C CB  1 
ATOM   6021  C CG  . TYR C 2 99  ? 154.145 155.167 86.972  1.00 85.87  ? 74  TYR C CG  1 
ATOM   6022  C CD1 . TYR C 2 99  ? 153.886 156.528 87.076  1.00 87.39  ? 74  TYR C CD1 1 
ATOM   6023  C CD2 . TYR C 2 99  ? 154.044 154.395 88.121  1.00 84.46  ? 74  TYR C CD2 1 
ATOM   6024  C CE1 . TYR C 2 99  ? 153.547 157.101 88.287  1.00 85.50  ? 74  TYR C CE1 1 
ATOM   6025  C CE2 . TYR C 2 99  ? 153.704 154.959 89.335  1.00 80.20  ? 74  TYR C CE2 1 
ATOM   6026  C CZ  . TYR C 2 99  ? 153.457 156.312 89.413  1.00 80.73  ? 74  TYR C CZ  1 
ATOM   6027  O OH  . TYR C 2 99  ? 153.118 156.876 90.622  1.00 76.56  ? 74  TYR C OH  1 
ATOM   6028  N N   . SER C 2 100 ? 156.458 156.592 84.048  1.00 102.07 ? 75  SER C N   1 
ATOM   6029  C CA  . SER C 2 100 ? 156.959 157.932 83.789  1.00 107.42 ? 75  SER C CA  1 
ATOM   6030  C C   . SER C 2 100 ? 155.874 158.763 83.121  1.00 112.76 ? 75  SER C C   1 
ATOM   6031  O O   . SER C 2 100 ? 154.975 158.229 82.465  1.00 113.38 ? 75  SER C O   1 
ATOM   6032  C CB  . SER C 2 100 ? 158.216 157.902 82.908  1.00 105.40 ? 75  SER C CB  1 
ATOM   6033  O OG  . SER C 2 100 ? 157.971 157.221 81.690  1.00 109.23 ? 75  SER C OG  1 
ATOM   6034  N N   . GLY C 2 101 ? 155.969 160.081 83.289  1.00 115.65 ? 76  GLY C N   1 
ATOM   6035  C CA  . GLY C 2 101 ? 155.009 161.010 82.739  1.00 115.04 ? 76  GLY C CA  1 
ATOM   6036  C C   . GLY C 2 101 ? 153.931 161.465 83.701  1.00 114.25 ? 76  GLY C C   1 
ATOM   6037  O O   . GLY C 2 101 ? 153.296 162.496 83.450  1.00 111.40 ? 76  GLY C O   1 
ATOM   6038  N N   . ILE C 2 102 ? 153.703 160.733 84.786  1.00 112.96 ? 77  ILE C N   1 
ATOM   6039  C CA  . ILE C 2 102 ? 152.690 161.093 85.770  1.00 108.14 ? 77  ILE C CA  1 
ATOM   6040  C C   . ILE C 2 102 ? 153.413 161.555 87.034  1.00 104.77 ? 77  ILE C C   1 
ATOM   6041  O O   . ILE C 2 102 ? 154.008 160.729 87.741  1.00 99.53  ? 77  ILE C O   1 
ATOM   6042  C CB  . ILE C 2 102 ? 151.747 159.921 86.070  1.00 103.14 ? 77  ILE C CB  1 
ATOM   6043  C CG1 . ILE C 2 102 ? 151.180 159.345 84.772  1.00 103.58 ? 77  ILE C CG1 1 
ATOM   6044  C CG2 . ILE C 2 102 ? 150.625 160.366 86.994  1.00 95.34  ? 77  ILE C CG2 1 
ATOM   6045  C CD1 . ILE C 2 102 ? 150.323 158.118 84.976  1.00 101.11 ? 77  ILE C CD1 1 
ATOM   6046  N N   . PRO C 2 103 ? 153.391 162.852 87.362  1.00 104.70 ? 78  PRO C N   1 
ATOM   6047  C CA  . PRO C 2 103 ? 154.065 163.351 88.567  1.00 99.95  ? 78  PRO C CA  1 
ATOM   6048  C C   . PRO C 2 103 ? 153.214 163.205 89.826  1.00 97.28  ? 78  PRO C C   1 
ATOM   6049  O O   . PRO C 2 103 ? 153.101 164.129 90.634  1.00 93.67  ? 78  PRO C O   1 
ATOM   6050  C CB  . PRO C 2 103 ? 154.322 164.820 88.221  1.00 95.47  ? 78  PRO C CB  1 
ATOM   6051  C CG  . PRO C 2 103 ? 153.146 165.187 87.377  1.00 94.91  ? 78  PRO C CG  1 
ATOM   6052  C CD  . PRO C 2 103 ? 152.788 163.946 86.580  1.00 103.19 ? 78  PRO C CD  1 
ATOM   6053  N N   . LEU C 2 104 ? 152.618 162.027 89.998  1.00 96.44  ? 79  LEU C N   1 
ATOM   6054  C CA  . LEU C 2 104 ? 151.730 161.752 91.115  1.00 92.82  ? 79  LEU C CA  1 
ATOM   6055  C C   . LEU C 2 104 ? 151.911 160.306 91.543  1.00 87.82  ? 79  LEU C C   1 
ATOM   6056  O O   . LEU C 2 104 ? 152.304 159.451 90.745  1.00 86.41  ? 79  LEU C O   1 
ATOM   6057  C CB  . LEU C 2 104 ? 150.260 162.007 90.749  1.00 93.73  ? 79  LEU C CB  1 
ATOM   6058  C CG  . LEU C 2 104 ? 149.831 163.451 90.487  1.00 98.29  ? 79  LEU C CG  1 
ATOM   6059  C CD1 . LEU C 2 104 ? 148.387 163.505 90.018  1.00 96.95  ? 79  LEU C CD1 1 
ATOM   6060  C CD2 . LEU C 2 104 ? 150.017 164.290 91.742  1.00 98.51  ? 79  LEU C CD2 1 
ATOM   6061  N N   . ASN C 2 105 ? 151.616 160.038 92.811  1.00 83.24  ? 80  ASN C N   1 
ATOM   6062  C CA  . ASN C 2 105 ? 151.681 158.686 93.352  1.00 78.14  ? 80  ASN C CA  1 
ATOM   6063  C C   . ASN C 2 105 ? 150.307 158.043 93.200  1.00 76.17  ? 80  ASN C C   1 
ATOM   6064  O O   . ASN C 2 105 ? 149.350 158.439 93.874  1.00 74.50  ? 80  ASN C O   1 
ATOM   6065  C CB  . ASN C 2 105 ? 152.143 158.733 94.805  1.00 75.21  ? 80  ASN C CB  1 
ATOM   6066  C CG  . ASN C 2 105 ? 153.489 159.413 94.946  1.00 84.19  ? 80  ASN C CG  1 
ATOM   6067  O OD1 . ASN C 2 105 ? 154.329 159.322 94.052  1.00 88.01  ? 80  ASN C OD1 1 
ATOM   6068  N ND2 . ASN C 2 105 ? 153.699 160.113 96.052  1.00 92.02  ? 80  ASN C ND2 1 
ATOM   6069  N N   . LEU C 2 106 ? 150.210 157.050 92.317  1.00 71.61  ? 81  LEU C N   1 
ATOM   6070  C CA  . LEU C 2 106 ? 148.922 156.457 91.971  1.00 63.33  ? 81  LEU C CA  1 
ATOM   6071  C C   . LEU C 2 106 ? 148.366 155.675 93.154  1.00 61.64  ? 81  LEU C C   1 
ATOM   6072  O O   . LEU C 2 106 ? 148.921 154.642 93.541  1.00 61.21  ? 81  LEU C O   1 
ATOM   6073  C CB  . LEU C 2 106 ? 149.072 155.552 90.753  1.00 62.14  ? 81  LEU C CB  1 
ATOM   6074  C CG  . LEU C 2 106 ? 149.626 156.195 89.484  1.00 75.04  ? 81  LEU C CG  1 
ATOM   6075  C CD1 . LEU C 2 106 ? 149.847 155.142 88.412  1.00 78.31  ? 81  LEU C CD1 1 
ATOM   6076  C CD2 . LEU C 2 106 ? 148.689 157.281 88.989  1.00 82.81  ? 81  LEU C CD2 1 
ATOM   6077  N N   . THR C 2 107 ? 147.268 156.161 93.724  1.00 62.50  ? 82  THR C N   1 
ATOM   6078  C CA  . THR C 2 107 ? 146.481 155.393 94.682  1.00 58.18  ? 82  THR C CA  1 
ATOM   6079  C C   . THR C 2 107 ? 145.388 154.664 93.911  1.00 59.90  ? 82  THR C C   1 
ATOM   6080  O O   . THR C 2 107 ? 144.497 155.299 93.337  1.00 61.72  ? 82  THR C O   1 
ATOM   6081  C CB  . THR C 2 107 ? 145.886 156.296 95.757  1.00 62.92  ? 82  THR C CB  1 
ATOM   6082  O OG1 . THR C 2 107 ? 146.936 157.023 96.408  1.00 64.98  ? 82  THR C OG1 1 
ATOM   6083  C CG2 . THR C 2 107 ? 145.140 155.463 96.784  1.00 60.22  ? 82  THR C CG2 1 
ATOM   6084  N N   . LEU C 2 108 ? 145.448 153.338 93.894  1.00 58.70  ? 83  LEU C N   1 
ATOM   6085  C CA  . LEU C 2 108 ? 144.560 152.544 93.060  1.00 59.71  ? 83  LEU C CA  1 
ATOM   6086  C C   . LEU C 2 108 ? 143.541 151.811 93.923  1.00 65.21  ? 83  LEU C C   1 
ATOM   6087  O O   . LEU C 2 108 ? 143.652 151.747 95.150  1.00 65.32  ? 83  LEU C O   1 
ATOM   6088  C CB  . LEU C 2 108 ? 145.359 151.547 92.213  1.00 56.31  ? 83  LEU C CB  1 
ATOM   6089  C CG  . LEU C 2 108 ? 146.361 152.150 91.227  1.00 57.63  ? 83  LEU C CG  1 
ATOM   6090  C CD1 . LEU C 2 108 ? 147.144 151.056 90.518  1.00 55.15  ? 83  LEU C CD1 1 
ATOM   6091  C CD2 . LEU C 2 108 ? 145.655 153.045 90.223  1.00 56.73  ? 83  LEU C CD2 1 
ATOM   6092  N N   . ASP C 2 109 ? 142.534 151.255 93.253  1.00 66.89  ? 84  ASP C N   1 
ATOM   6093  C CA  . ASP C 2 109 ? 141.533 150.446 93.930  1.00 66.42  ? 84  ASP C CA  1 
ATOM   6094  C C   . ASP C 2 109 ? 142.186 149.203 94.526  1.00 63.01  ? 84  ASP C C   1 
ATOM   6095  O O   . ASP C 2 109 ? 143.146 148.657 93.980  1.00 64.61  ? 84  ASP C O   1 
ATOM   6096  C CB  . ASP C 2 109 ? 140.419 150.056 92.955  1.00 65.77  ? 84  ASP C CB  1 
ATOM   6097  C CG  . ASP C 2 109 ? 139.303 149.258 93.613  1.00 73.89  ? 84  ASP C CG  1 
ATOM   6098  O OD1 . ASP C 2 109 ? 139.361 149.014 94.837  1.00 72.93  ? 84  ASP C OD1 1 
ATOM   6099  O OD2 . ASP C 2 109 ? 138.356 148.873 92.895  1.00 81.25  ? 84  ASP C OD2 1 
ATOM   6100  N N   . ASN C 2 110 ? 141.654 148.760 95.667  1.00 58.58  ? 85  ASN C N   1 
ATOM   6101  C CA  . ASN C 2 110 ? 142.234 147.623 96.372  1.00 57.25  ? 85  ASN C CA  1 
ATOM   6102  C C   . ASN C 2 110 ? 142.215 146.345 95.544  1.00 60.14  ? 85  ASN C C   1 
ATOM   6103  O O   . ASN C 2 110 ? 143.014 145.440 95.806  1.00 64.77  ? 85  ASN C O   1 
ATOM   6104  C CB  . ASN C 2 110 ? 141.494 147.396 97.692  1.00 54.75  ? 85  ASN C CB  1 
ATOM   6105  C CG  . ASN C 2 110 ? 140.069 146.912 97.490  1.00 60.74  ? 85  ASN C CG  1 
ATOM   6106  O OD1 . ASN C 2 110 ? 139.831 145.737 97.210  1.00 62.12  ? 85  ASN C OD1 1 
ATOM   6107  N ND2 . ASN C 2 110 ? 139.112 147.820 97.635  1.00 57.87  ? 85  ASN C ND2 1 
ATOM   6108  N N   . ARG C 2 111 ? 141.320 146.245 94.561  1.00 59.99  ? 86  ARG C N   1 
ATOM   6109  C CA  . ARG C 2 111 ? 141.236 145.040 93.746  1.00 64.17  ? 86  ARG C CA  1 
ATOM   6110  C C   . ARG C 2 111 ? 142.443 144.849 92.834  1.00 68.30  ? 86  ARG C C   1 
ATOM   6111  O O   . ARG C 2 111 ? 142.654 143.738 92.337  1.00 67.94  ? 86  ARG C O   1 
ATOM   6112  C CB  . ARG C 2 111 ? 139.950 145.079 92.921  1.00 67.55  ? 86  ARG C CB  1 
ATOM   6113  C CG  . ARG C 2 111 ? 138.711 144.718 93.721  1.00 71.98  ? 86  ARG C CG  1 
ATOM   6114  C CD  . ARG C 2 111 ? 137.438 144.950 92.927  1.00 77.94  ? 86  ARG C CD  1 
ATOM   6115  N NE  . ARG C 2 111 ? 137.056 146.357 92.940  1.00 79.94  ? 86  ARG C NE  1 
ATOM   6116  C CZ  . ARG C 2 111 ? 135.919 146.831 92.449  1.00 82.76  ? 86  ARG C CZ  1 
ATOM   6117  N NH1 . ARG C 2 111 ? 135.021 146.034 91.894  1.00 95.77  ? 86  ARG C NH1 1 
ATOM   6118  N NH2 . ARG C 2 111 ? 135.676 148.136 92.520  1.00 70.84  ? 86  ARG C NH2 1 
ATOM   6119  N N   . VAL C 2 112 ? 143.234 145.898 92.591  1.00 67.18  ? 87  VAL C N   1 
ATOM   6120  C CA  . VAL C 2 112 ? 144.436 145.739 91.779  1.00 64.49  ? 87  VAL C CA  1 
ATOM   6121  C C   . VAL C 2 112 ? 145.505 144.931 92.504  1.00 63.20  ? 87  VAL C C   1 
ATOM   6122  O O   . VAL C 2 112 ? 146.436 144.427 91.865  1.00 68.31  ? 87  VAL C O   1 
ATOM   6123  C CB  . VAL C 2 112 ? 144.999 147.109 91.353  1.00 63.84  ? 87  VAL C CB  1 
ATOM   6124  C CG1 . VAL C 2 112 ? 145.723 147.779 92.509  1.00 59.86  ? 87  VAL C CG1 1 
ATOM   6125  C CG2 . VAL C 2 112 ? 145.914 146.968 90.144  1.00 68.54  ? 87  VAL C CG2 1 
ATOM   6126  N N   . ALA C 2 113 ? 145.395 144.782 93.827  1.00 63.53  ? 88  ALA C N   1 
ATOM   6127  C CA  . ALA C 2 113 ? 146.388 144.020 94.577  1.00 67.13  ? 88  ALA C CA  1 
ATOM   6128  C C   . ALA C 2 113 ? 146.417 142.546 94.199  1.00 72.05  ? 88  ALA C C   1 
ATOM   6129  O O   . ALA C 2 113 ? 147.435 141.884 94.423  1.00 74.84  ? 88  ALA C O   1 
ATOM   6130  C CB  . ALA C 2 113 ? 146.133 144.162 96.077  1.00 54.16  ? 88  ALA C CB  1 
ATOM   6131  N N   . ASP C 2 114 ? 145.337 142.014 93.634  1.00 64.93  ? 89  ASP C N   1 
ATOM   6132  C CA  . ASP C 2 114 ? 145.311 140.605 93.268  1.00 67.28  ? 89  ASP C CA  1 
ATOM   6133  C C   . ASP C 2 114 ? 146.003 140.331 91.940  1.00 71.82  ? 89  ASP C C   1 
ATOM   6134  O O   . ASP C 2 114 ? 146.097 139.167 91.538  1.00 76.16  ? 89  ASP C O   1 
ATOM   6135  C CB  . ASP C 2 114 ? 143.867 140.103 93.216  1.00 76.68  ? 89  ASP C CB  1 
ATOM   6136  C CG  . ASP C 2 114 ? 143.180 140.161 94.568  1.00 82.98  ? 89  ASP C CG  1 
ATOM   6137  O OD1 . ASP C 2 114 ? 143.781 139.701 95.562  1.00 81.66  ? 89  ASP C OD1 1 
ATOM   6138  O OD2 . ASP C 2 114 ? 142.040 140.667 94.638  1.00 85.67  ? 89  ASP C OD2 1 
ATOM   6139  N N   . GLN C 2 115 ? 146.483 141.368 91.256  1.00 70.00  ? 90  GLN C N   1 
ATOM   6140  C CA  . GLN C 2 115 ? 147.134 141.229 89.962  1.00 64.91  ? 90  GLN C CA  1 
ATOM   6141  C C   . GLN C 2 115 ? 148.616 141.575 89.998  1.00 58.97  ? 90  GLN C C   1 
ATOM   6142  O O   . GLN C 2 115 ? 149.270 141.544 88.951  1.00 58.52  ? 90  GLN C O   1 
ATOM   6143  C CB  . GLN C 2 115 ? 146.414 142.093 88.922  1.00 71.03  ? 90  GLN C CB  1 
ATOM   6144  C CG  . GLN C 2 115 ? 144.969 141.673 88.700  1.00 78.16  ? 90  GLN C CG  1 
ATOM   6145  C CD  . GLN C 2 115 ? 144.085 142.814 88.246  1.00 84.18  ? 90  GLN C CD  1 
ATOM   6146  O OE1 . GLN C 2 115 ? 144.543 143.747 87.591  1.00 83.78  ? 90  GLN C OE1 1 
ATOM   6147  N NE2 . GLN C 2 115 ? 142.807 142.745 88.597  1.00 80.93  ? 90  GLN C NE2 1 
ATOM   6148  N N   . LEU C 2 116 ? 149.160 141.900 91.165  1.00 61.91  ? 91  LEU C N   1 
ATOM   6149  C CA  . LEU C 2 116 ? 150.565 142.240 91.331  1.00 64.72  ? 91  LEU C CA  1 
ATOM   6150  C C   . LEU C 2 116 ? 151.248 141.164 92.164  1.00 67.69  ? 91  LEU C C   1 
ATOM   6151  O O   . LEU C 2 116 ? 150.596 140.321 92.785  1.00 69.12  ? 91  LEU C O   1 
ATOM   6152  C CB  . LEU C 2 116 ? 150.723 143.608 92.003  1.00 59.11  ? 91  LEU C CB  1 
ATOM   6153  C CG  . LEU C 2 116 ? 150.061 144.811 91.334  1.00 55.22  ? 91  LEU C CG  1 
ATOM   6154  C CD1 . LEU C 2 116 ? 150.312 146.068 92.147  1.00 46.28  ? 91  LEU C CD1 1 
ATOM   6155  C CD2 . LEU C 2 116 ? 150.585 144.978 89.922  1.00 65.02  ? 91  LEU C CD2 1 
ATOM   6156  N N   . TRP C 2 117 ? 152.577 141.209 92.196  1.00 63.17  ? 92  TRP C N   1 
ATOM   6157  C CA  . TRP C 2 117 ? 153.314 140.401 93.155  1.00 61.06  ? 92  TRP C CA  1 
ATOM   6158  C C   . TRP C 2 117 ? 153.335 141.094 94.509  1.00 54.40  ? 92  TRP C C   1 
ATOM   6159  O O   . TRP C 2 117 ? 153.589 142.298 94.599  1.00 56.05  ? 92  TRP C O   1 
ATOM   6160  C CB  . TRP C 2 117 ? 154.743 140.147 92.676  1.00 61.37  ? 92  TRP C CB  1 
ATOM   6161  C CG  . TRP C 2 117 ? 155.536 139.283 93.615  1.00 59.70  ? 92  TRP C CG  1 
ATOM   6162  C CD1 . TRP C 2 117 ? 155.647 137.926 93.577  1.00 59.72  ? 92  TRP C CD1 1 
ATOM   6163  C CD2 . TRP C 2 117 ? 156.321 139.717 94.734  1.00 59.79  ? 92  TRP C CD2 1 
ATOM   6164  N NE1 . TRP C 2 117 ? 156.453 137.486 94.597  1.00 58.15  ? 92  TRP C NE1 1 
ATOM   6165  C CE2 . TRP C 2 117 ? 156.880 138.566 95.322  1.00 55.26  ? 92  TRP C CE2 1 
ATOM   6166  C CE3 . TRP C 2 117 ? 156.606 140.965 95.293  1.00 60.50  ? 92  TRP C CE3 1 
ATOM   6167  C CZ2 . TRP C 2 117 ? 157.706 138.626 96.441  1.00 52.02  ? 92  TRP C CZ2 1 
ATOM   6168  C CZ3 . TRP C 2 117 ? 157.429 141.022 96.403  1.00 56.89  ? 92  TRP C CZ3 1 
ATOM   6169  C CH2 . TRP C 2 117 ? 157.967 139.860 96.966  1.00 53.95  ? 92  TRP C CH2 1 
ATOM   6170  N N   . VAL C 2 118 ? 153.074 140.326 95.560  1.00 49.28  ? 93  VAL C N   1 
ATOM   6171  C CA  . VAL C 2 118 ? 153.150 140.822 96.928  1.00 47.34  ? 93  VAL C CA  1 
ATOM   6172  C C   . VAL C 2 118 ? 153.945 139.805 97.736  1.00 53.88  ? 93  VAL C C   1 
ATOM   6173  O O   . VAL C 2 118 ? 153.986 138.624 97.364  1.00 61.88  ? 93  VAL C O   1 
ATOM   6174  C CB  . VAL C 2 118 ? 151.752 141.051 97.520  1.00 47.07  ? 93  VAL C CB  1 
ATOM   6175  C CG1 . VAL C 2 118 ? 151.056 142.200 96.808  1.00 44.60  ? 93  VAL C CG1 1 
ATOM   6176  C CG2 . VAL C 2 118 ? 150.925 139.784 97.414  1.00 55.04  ? 93  VAL C CG2 1 
ATOM   6177  N N   . PRO C 2 119 ? 154.592 140.203 98.829  1.00 49.11  ? 94  PRO C N   1 
ATOM   6178  C CA  . PRO C 2 119 ? 155.348 139.231 99.622  1.00 47.38  ? 94  PRO C CA  1 
ATOM   6179  C C   . PRO C 2 119 ? 154.424 138.196 100.241 1.00 47.78  ? 94  PRO C C   1 
ATOM   6180  O O   . PRO C 2 119 ? 153.254 138.462 100.524 1.00 51.70  ? 94  PRO C O   1 
ATOM   6181  C CB  . PRO C 2 119 ? 156.032 140.091 100.691 1.00 45.15  ? 94  PRO C CB  1 
ATOM   6182  C CG  . PRO C 2 119 ? 155.991 141.480 100.157 1.00 45.21  ? 94  PRO C CG  1 
ATOM   6183  C CD  . PRO C 2 119 ? 154.738 141.569 99.353  1.00 45.92  ? 94  PRO C CD  1 
ATOM   6184  N N   . ASP C 2 120 ? 154.967 137.002 100.451 1.00 45.00  ? 95  ASP C N   1 
ATOM   6185  C CA  . ASP C 2 120 ? 154.232 135.918 101.100 1.00 46.97  ? 95  ASP C CA  1 
ATOM   6186  C C   . ASP C 2 120 ? 154.431 135.968 102.609 1.00 44.15  ? 95  ASP C C   1 
ATOM   6187  O O   . ASP C 2 120 ? 154.824 135.000 103.258 1.00 44.36  ? 95  ASP C O   1 
ATOM   6188  C CB  . ASP C 2 120 ? 154.673 134.578 100.528 1.00 54.84  ? 95  ASP C CB  1 
ATOM   6189  C CG  . ASP C 2 120 ? 156.170 134.375 100.619 1.00 57.86  ? 95  ASP C CG  1 
ATOM   6190  O OD1 . ASP C 2 120 ? 156.899 135.383 100.714 1.00 54.07  ? 95  ASP C OD1 1 
ATOM   6191  O OD2 . ASP C 2 120 ? 156.616 133.210 100.593 1.00 59.58  ? 95  ASP C OD2 1 
ATOM   6192  N N   . THR C 2 121 ? 154.147 137.139 103.168 1.00 38.71  ? 96  THR C N   1 
ATOM   6193  C CA  . THR C 2 121 ? 154.289 137.370 104.594 1.00 31.82  ? 96  THR C CA  1 
ATOM   6194  C C   . THR C 2 121 ? 153.144 136.735 105.368 1.00 34.34  ? 96  THR C C   1 
ATOM   6195  O O   . THR C 2 121 ? 151.984 136.794 104.951 1.00 43.38  ? 96  THR C O   1 
ATOM   6196  C CB  . THR C 2 121 ? 154.328 138.872 104.871 1.00 29.79  ? 96  THR C CB  1 
ATOM   6197  O OG1 . THR C 2 121 ? 155.379 139.476 104.106 1.00 33.11  ? 96  THR C OG1 1 
ATOM   6198  C CG2 . THR C 2 121 ? 154.548 139.140 106.332 1.00 25.42  ? 96  THR C CG2 1 
ATOM   6199  N N   . TYR C 2 122 ? 153.478 136.123 106.501 1.00 28.31  ? 97  TYR C N   1 
ATOM   6200  C CA  . TYR C 2 122 ? 152.491 135.551 107.401 1.00 25.57  ? 97  TYR C CA  1 
ATOM   6201  C C   . TYR C 2 122 ? 152.953 135.769 108.833 1.00 19.10  ? 97  TYR C C   1 
ATOM   6202  O O   . TYR C 2 122 ? 154.108 136.114 109.091 1.00 20.82  ? 97  TYR C O   1 
ATOM   6203  C CB  . TYR C 2 122 ? 152.263 134.060 107.118 1.00 31.69  ? 97  TYR C CB  1 
ATOM   6204  C CG  . TYR C 2 122 ? 153.357 133.146 107.626 1.00 31.96  ? 97  TYR C CG  1 
ATOM   6205  C CD1 . TYR C 2 122 ? 154.537 132.984 106.917 1.00 30.64  ? 97  TYR C CD1 1 
ATOM   6206  C CD2 . TYR C 2 122 ? 153.197 132.427 108.803 1.00 30.50  ? 97  TYR C CD2 1 
ATOM   6207  C CE1 . TYR C 2 122 ? 155.533 132.147 107.374 1.00 30.78  ? 97  TYR C CE1 1 
ATOM   6208  C CE2 . TYR C 2 122 ? 154.188 131.585 109.265 1.00 28.17  ? 97  TYR C CE2 1 
ATOM   6209  C CZ  . TYR C 2 122 ? 155.352 131.450 108.545 1.00 32.70  ? 97  TYR C CZ  1 
ATOM   6210  O OH  . TYR C 2 122 ? 156.346 130.615 108.998 1.00 40.47  ? 97  TYR C OH  1 
ATOM   6211  N N   . PHE C 2 123 ? 152.032 135.576 109.768 1.00 17.14  ? 98  PHE C N   1 
ATOM   6212  C CA  . PHE C 2 123 ? 152.308 135.755 111.185 1.00 16.62  ? 98  PHE C CA  1 
ATOM   6213  C C   . PHE C 2 123 ? 152.431 134.377 111.821 1.00 24.31  ? 98  PHE C C   1 
ATOM   6214  O O   . PHE C 2 123 ? 151.482 133.588 111.786 1.00 33.59  ? 98  PHE C O   1 
ATOM   6215  C CB  . PHE C 2 123 ? 151.209 136.579 111.852 1.00 18.54  ? 98  PHE C CB  1 
ATOM   6216  C CG  . PHE C 2 123 ? 150.932 137.881 111.161 1.00 20.64  ? 98  PHE C CG  1 
ATOM   6217  C CD1 . PHE C 2 123 ? 151.879 138.888 111.144 1.00 21.58  ? 98  PHE C CD1 1 
ATOM   6218  C CD2 . PHE C 2 123 ? 149.733 138.089 110.504 1.00 18.53  ? 98  PHE C CD2 1 
ATOM   6219  C CE1 . PHE C 2 123 ? 151.628 140.082 110.500 1.00 17.13  ? 98  PHE C CE1 1 
ATOM   6220  C CE2 . PHE C 2 123 ? 149.479 139.280 109.858 1.00 13.82  ? 98  PHE C CE2 1 
ATOM   6221  C CZ  . PHE C 2 123 ? 150.428 140.275 109.856 1.00 13.27  ? 98  PHE C CZ  1 
ATOM   6222  N N   . LEU C 2 124 ? 153.603 134.090 112.391 1.00 22.23  ? 99  LEU C N   1 
ATOM   6223  C CA  . LEU C 2 124 ? 153.914 132.725 112.803 1.00 21.41  ? 99  LEU C CA  1 
ATOM   6224  C C   . LEU C 2 124 ? 152.990 132.252 113.919 1.00 26.97  ? 99  LEU C C   1 
ATOM   6225  O O   . LEU C 2 124 ? 152.499 131.117 113.885 1.00 37.79  ? 99  LEU C O   1 
ATOM   6226  C CB  . LEU C 2 124 ? 155.380 132.637 113.231 1.00 22.40  ? 99  LEU C CB  1 
ATOM   6227  C CG  . LEU C 2 124 ? 156.132 131.309 113.075 1.00 26.12  ? 99  LEU C CG  1 
ATOM   6228  C CD1 . LEU C 2 124 ? 157.616 131.528 113.313 1.00 39.83  ? 99  LEU C CD1 1 
ATOM   6229  C CD2 . LEU C 2 124 ? 155.609 130.230 114.012 1.00 23.28  ? 99  LEU C CD2 1 
ATOM   6230  N N   . ASN C 2 125 ? 152.737 133.101 114.914 1.00 23.12  ? 100 ASN C N   1 
ATOM   6231  C CA  . ASN C 2 125 ? 151.936 132.731 116.074 1.00 23.72  ? 100 ASN C CA  1 
ATOM   6232  C C   . ASN C 2 125 ? 150.478 133.159 115.943 1.00 24.96  ? 100 ASN C C   1 
ATOM   6233  O O   . ASN C 2 125 ? 149.803 133.369 116.956 1.00 29.14  ? 100 ASN C O   1 
ATOM   6234  C CB  . ASN C 2 125 ? 152.549 133.317 117.345 1.00 22.32  ? 100 ASN C CB  1 
ATOM   6235  C CG  . ASN C 2 125 ? 152.550 134.830 117.348 1.00 23.83  ? 100 ASN C CG  1 
ATOM   6236  O OD1 . ASN C 2 125 ? 152.692 135.463 116.305 1.00 23.06  ? 100 ASN C OD1 1 
ATOM   6237  N ND2 . ASN C 2 125 ? 152.397 135.418 118.526 1.00 29.33  ? 100 ASN C ND2 1 
ATOM   6238  N N   . ASP C 2 126 ? 149.972 133.280 114.720 1.00 22.08  ? 101 ASP C N   1 
ATOM   6239  C CA  . ASP C 2 126 ? 148.627 133.791 114.487 1.00 20.48  ? 101 ASP C CA  1 
ATOM   6240  C C   . ASP C 2 126 ? 147.625 132.642 114.497 1.00 21.43  ? 101 ASP C C   1 
ATOM   6241  O O   . ASP C 2 126 ? 147.706 131.733 113.665 1.00 24.91  ? 101 ASP C O   1 
ATOM   6242  C CB  . ASP C 2 126 ? 148.570 134.541 113.159 1.00 20.77  ? 101 ASP C CB  1 
ATOM   6243  C CG  . ASP C 2 126 ? 147.168 134.631 112.597 1.00 23.40  ? 101 ASP C CG  1 
ATOM   6244  O OD1 . ASP C 2 126 ? 146.340 135.360 113.177 1.00 29.22  ? 101 ASP C OD1 1 
ATOM   6245  O OD2 . ASP C 2 126 ? 146.897 133.976 111.569 1.00 23.40  ? 101 ASP C OD2 1 
ATOM   6246  N N   . LYS C 2 127 ? 146.684 132.686 115.441 1.00 21.15  ? 102 LYS C N   1 
ATOM   6247  C CA  . LYS C 2 127 ? 145.673 131.639 115.553 1.00 20.81  ? 102 LYS C CA  1 
ATOM   6248  C C   . LYS C 2 127 ? 144.533 131.863 114.567 1.00 21.20  ? 102 LYS C C   1 
ATOM   6249  O O   . LYS C 2 127 ? 144.102 130.931 113.881 1.00 20.96  ? 102 LYS C O   1 
ATOM   6250  C CB  . LYS C 2 127 ? 145.149 131.566 116.987 1.00 21.72  ? 102 LYS C CB  1 
ATOM   6251  C CG  . LYS C 2 127 ? 146.244 131.368 118.015 1.00 24.28  ? 102 LYS C CG  1 
ATOM   6252  C CD  . LYS C 2 127 ? 145.704 131.432 119.428 1.00 33.44  ? 102 LYS C CD  1 
ATOM   6253  C CE  . LYS C 2 127 ? 144.807 130.249 119.733 1.00 39.71  ? 102 LYS C CE  1 
ATOM   6254  N NZ  . LYS C 2 127 ? 144.407 130.224 121.166 1.00 40.15  ? 102 LYS C NZ  1 
ATOM   6255  N N   . LYS C 2 128 ? 144.023 133.089 114.495 1.00 22.62  ? 103 LYS C N   1 
ATOM   6256  C CA  . LYS C 2 128 ? 142.983 133.436 113.539 1.00 22.10  ? 103 LYS C CA  1 
ATOM   6257  C C   . LYS C 2 128 ? 143.094 134.919 113.225 1.00 23.75  ? 103 LYS C C   1 
ATOM   6258  O O   . LYS C 2 128 ? 143.374 135.727 114.113 1.00 25.76  ? 103 LYS C O   1 
ATOM   6259  C CB  . LYS C 2 128 ? 141.591 133.114 114.090 1.00 23.38  ? 103 LYS C CB  1 
ATOM   6260  C CG  . LYS C 2 128 ? 140.460 133.315 113.099 1.00 35.31  ? 103 LYS C CG  1 
ATOM   6261  C CD  . LYS C 2 128 ? 139.113 133.204 113.790 1.00 38.02  ? 103 LYS C CD  1 
ATOM   6262  C CE  . LYS C 2 128 ? 137.972 133.515 112.839 1.00 38.39  ? 103 LYS C CE  1 
ATOM   6263  N NZ  . LYS C 2 128 ? 136.653 133.405 113.520 1.00 41.34  ? 103 LYS C NZ  1 
ATOM   6264  N N   . SER C 2 129 ? 142.858 135.269 111.964 1.00 21.40  ? 104 SER C N   1 
ATOM   6265  C CA  . SER C 2 129 ? 142.937 136.658 111.541 1.00 21.52  ? 104 SER C CA  1 
ATOM   6266  C C   . SER C 2 129 ? 142.122 136.845 110.273 1.00 26.85  ? 104 SER C C   1 
ATOM   6267  O O   . SER C 2 129 ? 141.780 135.882 109.583 1.00 32.66  ? 104 SER C O   1 
ATOM   6268  C CB  . SER C 2 129 ? 144.387 137.088 111.311 1.00 21.30  ? 104 SER C CB  1 
ATOM   6269  O OG  . SER C 2 129 ? 144.996 136.297 110.309 1.00 23.22  ? 104 SER C OG  1 
ATOM   6270  N N   . PHE C 2 130 ? 141.819 138.105 109.975 1.00 25.85  ? 105 PHE C N   1 
ATOM   6271  C CA  . PHE C 2 130 ? 141.075 138.436 108.771 1.00 23.63  ? 105 PHE C CA  1 
ATOM   6272  C C   . PHE C 2 130 ? 141.364 139.882 108.400 1.00 23.27  ? 105 PHE C C   1 
ATOM   6273  O O   . PHE C 2 130 ? 141.819 140.676 109.226 1.00 25.33  ? 105 PHE C O   1 
ATOM   6274  C CB  . PHE C 2 130 ? 139.571 138.211 108.962 1.00 27.41  ? 105 PHE C CB  1 
ATOM   6275  C CG  . PHE C 2 130 ? 138.978 138.993 110.100 1.00 27.30  ? 105 PHE C CG  1 
ATOM   6276  C CD1 . PHE C 2 130 ? 138.999 138.489 111.388 1.00 28.07  ? 105 PHE C CD1 1 
ATOM   6277  C CD2 . PHE C 2 130 ? 138.388 140.224 109.879 1.00 26.76  ? 105 PHE C CD2 1 
ATOM   6278  C CE1 . PHE C 2 130 ? 138.453 139.204 112.434 1.00 28.37  ? 105 PHE C CE1 1 
ATOM   6279  C CE2 . PHE C 2 130 ? 137.840 140.941 110.921 1.00 27.90  ? 105 PHE C CE2 1 
ATOM   6280  C CZ  . PHE C 2 130 ? 137.872 140.430 112.199 1.00 28.04  ? 105 PHE C CZ  1 
ATOM   6281  N N   . VAL C 2 131 ? 141.085 140.212 107.143 1.00 25.45  ? 106 VAL C N   1 
ATOM   6282  C CA  . VAL C 2 131 ? 141.086 141.588 106.664 1.00 25.03  ? 106 VAL C CA  1 
ATOM   6283  C C   . VAL C 2 131 ? 139.651 142.085 106.666 1.00 33.48  ? 106 VAL C C   1 
ATOM   6284  O O   . VAL C 2 131 ? 138.751 141.405 106.157 1.00 34.73  ? 106 VAL C O   1 
ATOM   6285  C CB  . VAL C 2 131 ? 141.708 141.701 105.262 1.00 21.49  ? 106 VAL C CB  1 
ATOM   6286  C CG1 . VAL C 2 131 ? 141.732 143.147 104.813 1.00 23.41  ? 106 VAL C CG1 1 
ATOM   6287  C CG2 . VAL C 2 131 ? 143.113 141.146 105.264 1.00 17.89  ? 106 VAL C CG2 1 
ATOM   6288  N N   . HIS C 2 132 ? 139.434 143.264 107.238 1.00 31.63  ? 107 HIS C N   1 
ATOM   6289  C CA  . HIS C 2 132 ? 138.098 143.834 107.287 1.00 31.35  ? 107 HIS C CA  1 
ATOM   6290  C C   . HIS C 2 132 ? 137.573 144.059 105.874 1.00 32.76  ? 107 HIS C C   1 
ATOM   6291  O O   . HIS C 2 132 ? 138.325 144.382 104.951 1.00 32.75  ? 107 HIS C O   1 
ATOM   6292  C CB  . HIS C 2 132 ? 138.117 145.143 108.072 1.00 28.39  ? 107 HIS C CB  1 
ATOM   6293  C CG  . HIS C 2 132 ? 138.548 144.981 109.496 1.00 24.80  ? 107 HIS C CG  1 
ATOM   6294  N ND1 . HIS C 2 132 ? 137.727 145.275 110.562 1.00 29.91  ? 107 HIS C ND1 1 
ATOM   6295  C CD2 . HIS C 2 132 ? 139.715 144.548 110.030 1.00 22.14  ? 107 HIS C CD2 1 
ATOM   6296  C CE1 . HIS C 2 132 ? 138.371 145.036 111.690 1.00 22.96  ? 107 HIS C CE1 1 
ATOM   6297  N NE2 . HIS C 2 132 ? 139.578 144.592 111.395 1.00 19.06  ? 107 HIS C NE2 1 
ATOM   6298  N N   . GLY C 2 133 ? 136.266 143.877 105.705 1.00 30.50  ? 108 GLY C N   1 
ATOM   6299  C CA  . GLY C 2 133 ? 135.698 143.844 104.374 1.00 31.58  ? 108 GLY C CA  1 
ATOM   6300  C C   . GLY C 2 133 ? 134.524 144.774 104.154 1.00 34.38  ? 108 GLY C C   1 
ATOM   6301  O O   . GLY C 2 133 ? 133.788 144.623 103.175 1.00 41.27  ? 108 GLY C O   1 
ATOM   6302  N N   . VAL C 2 134 ? 134.329 145.732 105.055 1.00 34.05  ? 109 VAL C N   1 
ATOM   6303  C CA  . VAL C 2 134 ? 133.230 146.686 104.969 1.00 32.18  ? 109 VAL C CA  1 
ATOM   6304  C C   . VAL C 2 134 ? 133.818 148.090 104.971 1.00 30.12  ? 109 VAL C C   1 
ATOM   6305  O O   . VAL C 2 134 ? 134.662 148.406 105.816 1.00 38.93  ? 109 VAL C O   1 
ATOM   6306  C CB  . VAL C 2 134 ? 132.242 146.503 106.136 1.00 34.94  ? 109 VAL C CB  1 
ATOM   6307  C CG1 . VAL C 2 134 ? 131.178 147.585 106.136 1.00 36.25  ? 109 VAL C CG1 1 
ATOM   6308  C CG2 . VAL C 2 134 ? 131.603 145.126 106.079 1.00 37.28  ? 109 VAL C CG2 1 
ATOM   6309  N N   . THR C 2 135 ? 133.371 148.934 104.039 1.00 27.43  ? 110 THR C N   1 
ATOM   6310  C CA  . THR C 2 135 ? 132.394 148.578 103.012 1.00 32.07  ? 110 THR C CA  1 
ATOM   6311  C C   . THR C 2 135 ? 133.050 147.767 101.896 1.00 41.27  ? 110 THR C C   1 
ATOM   6312  O O   . THR C 2 135 ? 132.415 146.915 101.275 1.00 44.77  ? 110 THR C O   1 
ATOM   6313  C CB  . THR C 2 135 ? 131.728 149.826 102.412 1.00 31.13  ? 110 THR C CB  1 
ATOM   6314  O OG1 . THR C 2 135 ? 132.708 150.607 101.719 1.00 36.13  ? 110 THR C OG1 1 
ATOM   6315  C CG2 . THR C 2 135 ? 131.110 150.671 103.510 1.00 33.03  ? 110 THR C CG2 1 
ATOM   6316  N N   . VAL C 2 136 ? 134.326 148.053 101.641 1.00 37.95  ? 111 VAL C N   1 
ATOM   6317  C CA  . VAL C 2 136 ? 135.126 147.282 100.697 1.00 37.33  ? 111 VAL C CA  1 
ATOM   6318  C C   . VAL C 2 136 ? 136.235 146.590 101.477 1.00 33.74  ? 111 VAL C C   1 
ATOM   6319  O O   . VAL C 2 136 ? 136.386 146.811 102.684 1.00 29.81  ? 111 VAL C O   1 
ATOM   6320  C CB  . VAL C 2 136 ? 135.700 148.169 99.579  1.00 36.46  ? 111 VAL C CB  1 
ATOM   6321  C CG1 . VAL C 2 136 ? 134.578 148.857 98.825  1.00 37.41  ? 111 VAL C CG1 1 
ATOM   6322  C CG2 . VAL C 2 136 ? 136.662 149.190 100.161 1.00 29.64  ? 111 VAL C CG2 1 
ATOM   6323  N N   . LYS C 2 137 ? 137.016 145.751 100.800 1.00 34.16  ? 112 LYS C N   1 
ATOM   6324  C CA  . LYS C 2 137 ? 138.133 145.091 101.462 1.00 33.33  ? 112 LYS C CA  1 
ATOM   6325  C C   . LYS C 2 137 ? 139.175 146.114 101.897 1.00 35.11  ? 112 LYS C C   1 
ATOM   6326  O O   . LYS C 2 137 ? 139.650 146.919 101.092 1.00 41.24  ? 112 LYS C O   1 
ATOM   6327  C CB  . LYS C 2 137 ? 138.762 144.054 100.531 1.00 35.98  ? 112 LYS C CB  1 
ATOM   6328  C CG  . LYS C 2 137 ? 139.757 143.140 101.224 1.00 38.57  ? 112 LYS C CG  1 
ATOM   6329  C CD  . LYS C 2 137 ? 140.218 142.017 100.313 1.00 44.08  ? 112 LYS C CD  1 
ATOM   6330  C CE  . LYS C 2 137 ? 141.204 141.106 101.029 1.00 45.54  ? 112 LYS C CE  1 
ATOM   6331  N NZ  . LYS C 2 137 ? 141.583 139.928 100.203 1.00 45.35  ? 112 LYS C NZ  1 
ATOM   6332  N N   . ASN C 2 138 ? 139.535 146.073 103.180 1.00 28.60  ? 113 ASN C N   1 
ATOM   6333  C CA  . ASN C 2 138 ? 140.404 147.082 103.773 1.00 22.98  ? 113 ASN C CA  1 
ATOM   6334  C C   . ASN C 2 138 ? 141.842 146.871 103.314 1.00 23.98  ? 113 ASN C C   1 
ATOM   6335  O O   . ASN C 2 138 ? 142.680 146.384 104.078 1.00 24.57  ? 113 ASN C O   1 
ATOM   6336  C CB  . ASN C 2 138 ? 140.310 147.037 105.299 1.00 23.82  ? 113 ASN C CB  1 
ATOM   6337  C CG  . ASN C 2 138 ? 139.036 147.672 105.827 1.00 23.98  ? 113 ASN C CG  1 
ATOM   6338  O OD1 . ASN C 2 138 ? 138.996 148.164 106.953 1.00 21.53  ? 113 ASN C OD1 1 
ATOM   6339  N ND2 . ASN C 2 138 ? 137.990 147.669 105.012 1.00 27.34  ? 113 ASN C ND2 1 
ATOM   6340  N N   . ARG C 2 139 ? 142.128 147.225 102.064 1.00 28.12  ? 114 ARG C N   1 
ATOM   6341  C CA  . ARG C 2 139 ? 143.413 146.955 101.439 1.00 28.15  ? 114 ARG C CA  1 
ATOM   6342  C C   . ARG C 2 139 ? 143.810 148.153 100.586 1.00 29.03  ? 114 ARG C C   1 
ATOM   6343  O O   . ARG C 2 139 ? 142.952 148.854 100.044 1.00 34.84  ? 114 ARG C O   1 
ATOM   6344  C CB  . ARG C 2 139 ? 143.344 145.665 100.612 1.00 30.00  ? 114 ARG C CB  1 
ATOM   6345  C CG  . ARG C 2 139 ? 144.606 145.291 99.874  1.00 34.41  ? 114 ARG C CG  1 
ATOM   6346  C CD  . ARG C 2 139 ? 144.420 143.954 99.185  1.00 45.85  ? 114 ARG C CD  1 
ATOM   6347  N NE  . ARG C 2 139 ? 143.193 143.918 98.400  1.00 58.22  ? 114 ARG C NE  1 
ATOM   6348  C CZ  . ARG C 2 139 ? 142.736 142.843 97.773  1.00 62.86  ? 114 ARG C CZ  1 
ATOM   6349  N NH1 . ARG C 2 139 ? 143.395 141.696 97.798  1.00 63.86  ? 114 ARG C NH1 1 
ATOM   6350  N NH2 . ARG C 2 139 ? 141.592 142.921 97.101  1.00 59.05  ? 114 ARG C NH2 1 
ATOM   6351  N N   . MET C 2 140 ? 145.115 148.400 100.487 1.00 25.84  ? 115 MET C N   1 
ATOM   6352  C CA  . MET C 2 140 ? 145.618 149.589 99.813  1.00 25.06  ? 115 MET C CA  1 
ATOM   6353  C C   . MET C 2 140 ? 146.833 149.248 98.964  1.00 29.14  ? 115 MET C C   1 
ATOM   6354  O O   . MET C 2 140 ? 147.718 148.508 99.398  1.00 35.08  ? 115 MET C O   1 
ATOM   6355  C CB  . MET C 2 140 ? 145.985 150.683 100.825 1.00 30.56  ? 115 MET C CB  1 
ATOM   6356  C CG  . MET C 2 140 ? 146.658 151.900 100.212 1.00 39.76  ? 115 MET C CG  1 
ATOM   6357  S SD  . MET C 2 140 ? 147.035 153.179 101.424 1.00 76.38  ? 115 MET C SD  1 
ATOM   6358  C CE  . MET C 2 140 ? 148.124 152.288 102.528 1.00 48.23  ? 115 MET C CE  1 
ATOM   6359  N N   . ILE C 2 141 ? 146.866 149.799 97.752  1.00 34.12  ? 116 ILE C N   1 
ATOM   6360  C CA  . ILE C 2 141 ? 148.024 149.730 96.868  1.00 38.26  ? 116 ILE C CA  1 
ATOM   6361  C C   . ILE C 2 141 ? 148.349 151.137 96.392  1.00 46.75  ? 116 ILE C C   1 
ATOM   6362  O O   . ILE C 2 141 ? 147.467 151.852 95.905  1.00 57.99  ? 116 ILE C O   1 
ATOM   6363  C CB  . ILE C 2 141 ? 147.773 148.806 95.660  1.00 42.54  ? 116 ILE C CB  1 
ATOM   6364  C CG1 . ILE C 2 141 ? 147.958 147.342 96.046  1.00 41.74  ? 116 ILE C CG1 1 
ATOM   6365  C CG2 . ILE C 2 141 ? 148.694 149.166 94.505  1.00 43.63  ? 116 ILE C CG2 1 
ATOM   6366  C CD1 . ILE C 2 141 ? 149.409 146.945 96.168  1.00 41.49  ? 116 ILE C CD1 1 
ATOM   6367  N N   . ARG C 2 142 ? 149.613 151.531 96.529  1.00 45.08  ? 117 ARG C N   1 
ATOM   6368  C CA  . ARG C 2 142 ? 150.078 152.840 96.089  1.00 46.78  ? 117 ARG C CA  1 
ATOM   6369  C C   . ARG C 2 142 ? 151.386 152.654 95.338  1.00 43.94  ? 117 ARG C C   1 
ATOM   6370  O O   . ARG C 2 142 ? 152.359 152.144 95.901  1.00 47.23  ? 117 ARG C O   1 
ATOM   6371  C CB  . ARG C 2 142 ? 150.256 153.790 97.275  1.00 47.58  ? 117 ARG C CB  1 
ATOM   6372  C CG  . ARG C 2 142 ? 150.664 155.200 96.892  1.00 52.33  ? 117 ARG C CG  1 
ATOM   6373  C CD  . ARG C 2 142 ? 150.768 156.085 98.122  1.00 49.82  ? 117 ARG C CD  1 
ATOM   6374  N NE  . ARG C 2 142 ? 149.484 156.224 98.797  1.00 54.19  ? 117 ARG C NE  1 
ATOM   6375  C CZ  . ARG C 2 142 ? 149.291 156.927 99.904  1.00 52.58  ? 117 ARG C CZ  1 
ATOM   6376  N NH1 . ARG C 2 142 ? 150.282 157.577 100.492 1.00 51.61  ? 117 ARG C NH1 1 
ATOM   6377  N NH2 . ARG C 2 142 ? 148.072 156.983 100.434 1.00 52.98  ? 117 ARG C NH2 1 
ATOM   6378  N N   . LEU C 2 143 ? 151.410 153.072 94.079  1.00 47.91  ? 118 LEU C N   1 
ATOM   6379  C CA  . LEU C 2 143 ? 152.597 152.987 93.242  1.00 56.27  ? 118 LEU C CA  1 
ATOM   6380  C C   . LEU C 2 143 ? 153.320 154.328 93.207  1.00 66.81  ? 118 LEU C C   1 
ATOM   6381  O O   . LEU C 2 143 ? 152.733 155.385 93.447  1.00 73.47  ? 118 LEU C O   1 
ATOM   6382  C CB  . LEU C 2 143 ? 152.231 152.548 91.822  1.00 60.22  ? 118 LEU C CB  1 
ATOM   6383  C CG  . LEU C 2 143 ? 151.469 151.227 91.709  1.00 62.48  ? 118 LEU C CG  1 
ATOM   6384  C CD1 . LEU C 2 143 ? 151.168 150.900 90.256  1.00 65.71  ? 118 LEU C CD1 1 
ATOM   6385  C CD2 . LEU C 2 143 ? 152.253 150.102 92.359  1.00 60.90  ? 118 LEU C CD2 1 
ATOM   6386  N N   . HIS C 2 144 ? 154.607 154.270 92.902  1.00 69.94  ? 119 HIS C N   1 
ATOM   6387  C CA  . HIS C 2 144 ? 155.453 155.444 92.781  1.00 73.70  ? 119 HIS C CA  1 
ATOM   6388  C C   . HIS C 2 144 ? 156.236 155.366 91.481  1.00 81.44  ? 119 HIS C C   1 
ATOM   6389  O O   . HIS C 2 144 ? 156.445 154.275 90.940  1.00 81.10  ? 119 HIS C O   1 
ATOM   6390  C CB  . HIS C 2 144 ? 156.415 155.545 93.975  1.00 66.92  ? 119 HIS C CB  1 
ATOM   6391  C CG  . HIS C 2 144 ? 155.724 155.653 95.299  1.00 64.07  ? 119 HIS C CG  1 
ATOM   6392  N ND1 . HIS C 2 144 ? 155.030 154.606 95.864  1.00 57.67  ? 119 HIS C ND1 1 
ATOM   6393  C CD2 . HIS C 2 144 ? 155.622 156.685 96.169  1.00 65.92  ? 119 HIS C CD2 1 
ATOM   6394  C CE1 . HIS C 2 144 ? 154.529 154.987 97.025  1.00 54.77  ? 119 HIS C CE1 1 
ATOM   6395  N NE2 . HIS C 2 144 ? 154.875 156.245 97.234  1.00 59.39  ? 119 HIS C NE2 1 
ATOM   6396  N N   . PRO C 2 145 ? 156.663 156.515 90.938  1.00 84.82  ? 120 PRO C N   1 
ATOM   6397  C CA  . PRO C 2 145 ? 157.289 156.499 89.602  1.00 84.37  ? 120 PRO C CA  1 
ATOM   6398  C C   . PRO C 2 145 ? 158.497 155.584 89.496  1.00 83.55  ? 120 PRO C C   1 
ATOM   6399  O O   . PRO C 2 145 ? 158.692 154.943 88.456  1.00 83.33  ? 120 PRO C O   1 
ATOM   6400  C CB  . PRO C 2 145 ? 157.666 157.970 89.377  1.00 83.21  ? 120 PRO C CB  1 
ATOM   6401  C CG  . PRO C 2 145 ? 156.759 158.738 90.274  1.00 81.54  ? 120 PRO C CG  1 
ATOM   6402  C CD  . PRO C 2 145 ? 156.559 157.881 91.480  1.00 78.96  ? 120 PRO C CD  1 
ATOM   6403  N N   . ASP C 2 146 ? 159.314 155.497 90.543  1.00 83.40  ? 121 ASP C N   1 
ATOM   6404  C CA  . ASP C 2 146 ? 160.528 154.693 90.501  1.00 86.84  ? 121 ASP C CA  1 
ATOM   6405  C C   . ASP C 2 146 ? 160.268 153.206 90.716  1.00 90.41  ? 121 ASP C C   1 
ATOM   6406  O O   . ASP C 2 146 ? 161.220 152.455 90.953  1.00 92.29  ? 121 ASP C O   1 
ATOM   6407  C CB  . ASP C 2 146 ? 161.531 155.203 91.541  1.00 88.59  ? 121 ASP C CB  1 
ATOM   6408  C CG  . ASP C 2 146 ? 160.992 155.136 92.961  1.00 89.83  ? 121 ASP C CG  1 
ATOM   6409  O OD1 . ASP C 2 146 ? 159.815 154.762 93.145  1.00 89.04  ? 121 ASP C OD1 1 
ATOM   6410  O OD2 . ASP C 2 146 ? 161.751 155.459 93.898  1.00 92.16  ? 121 ASP C OD2 1 
ATOM   6411  N N   . GLY C 2 147 ? 159.015 152.767 90.635  1.00 86.60  ? 122 GLY C N   1 
ATOM   6412  C CA  . GLY C 2 147 ? 158.689 151.368 90.809  1.00 82.18  ? 122 GLY C CA  1 
ATOM   6413  C C   . GLY C 2 147 ? 158.517 150.924 92.242  1.00 74.57  ? 122 GLY C C   1 
ATOM   6414  O O   . GLY C 2 147 ? 158.399 149.718 92.490  1.00 72.32  ? 122 GLY C O   1 
ATOM   6415  N N   . THR C 2 148 ? 158.495 151.853 93.193  1.00 68.56  ? 123 THR C N   1 
ATOM   6416  C CA  . THR C 2 148 ? 158.325 151.502 94.595  1.00 62.12  ? 123 THR C CA  1 
ATOM   6417  C C   . THR C 2 148 ? 156.854 151.245 94.891  1.00 56.13  ? 123 THR C C   1 
ATOM   6418  O O   . THR C 2 148 ? 155.989 152.039 94.512  1.00 64.97  ? 123 THR C O   1 
ATOM   6419  C CB  . THR C 2 148 ? 158.859 152.619 95.487  1.00 67.93  ? 123 THR C CB  1 
ATOM   6420  O OG1 . THR C 2 148 ? 160.290 152.649 95.415  1.00 79.12  ? 123 THR C OG1 1 
ATOM   6421  C CG2 . THR C 2 148 ? 158.436 152.396 96.919  1.00 56.24  ? 123 THR C CG2 1 
ATOM   6422  N N   . VAL C 2 149 ? 156.573 150.142 95.579  1.00 49.56  ? 124 VAL C N   1 
ATOM   6423  C CA  . VAL C 2 149 ? 155.212 149.736 95.904  1.00 45.12  ? 124 VAL C CA  1 
ATOM   6424  C C   . VAL C 2 149 ? 155.003 149.868 97.405  1.00 37.20  ? 124 VAL C C   1 
ATOM   6425  O O   . VAL C 2 149 ? 155.811 149.372 98.198  1.00 41.46  ? 124 VAL C O   1 
ATOM   6426  C CB  . VAL C 2 149 ? 154.928 148.299 95.437  1.00 40.79  ? 124 VAL C CB  1 
ATOM   6427  C CG1 . VAL C 2 149 ? 153.438 148.019 95.462  1.00 40.46  ? 124 VAL C CG1 1 
ATOM   6428  C CG2 . VAL C 2 149 ? 155.488 148.079 94.046  1.00 46.90  ? 124 VAL C CG2 1 
ATOM   6429  N N   . LEU C 2 150 ? 153.925 150.539 97.790  1.00 34.15  ? 125 LEU C N   1 
ATOM   6430  C CA  . LEU C 2 150 ? 153.465 150.585 99.169  1.00 27.74  ? 125 LEU C CA  1 
ATOM   6431  C C   . LEU C 2 150 ? 152.158 149.814 99.263  1.00 29.13  ? 125 LEU C C   1 
ATOM   6432  O O   . LEU C 2 150 ? 151.223 150.079 98.502  1.00 36.74  ? 125 LEU C O   1 
ATOM   6433  C CB  . LEU C 2 150 ? 153.265 152.025 99.641  1.00 33.55  ? 125 LEU C CB  1 
ATOM   6434  C CG  . LEU C 2 150 ? 152.494 152.212 100.951 1.00 32.32  ? 125 LEU C CG  1 
ATOM   6435  C CD1 . LEU C 2 150 ? 153.187 151.505 102.106 1.00 33.34  ? 125 LEU C CD1 1 
ATOM   6436  C CD2 . LEU C 2 150 ? 152.308 153.688 101.260 1.00 40.50  ? 125 LEU C CD2 1 
ATOM   6437  N N   . TYR C 2 151 ? 152.094 148.866 100.194 1.00 27.79  ? 126 TYR C N   1 
ATOM   6438  C CA  . TYR C 2 151 ? 150.998 147.906 100.255 1.00 27.83  ? 126 TYR C CA  1 
ATOM   6439  C C   . TYR C 2 151 ? 150.541 147.849 101.705 1.00 23.42  ? 126 TYR C C   1 
ATOM   6440  O O   . TYR C 2 151 ? 151.270 147.358 102.572 1.00 26.27  ? 126 TYR C O   1 
ATOM   6441  C CB  . TYR C 2 151 ? 151.446 146.536 99.741  1.00 29.98  ? 126 TYR C CB  1 
ATOM   6442  C CG  . TYR C 2 151 ? 150.387 145.457 99.751  1.00 29.44  ? 126 TYR C CG  1 
ATOM   6443  C CD1 . TYR C 2 151 ? 149.102 145.716 99.302  1.00 28.91  ? 126 TYR C CD1 1 
ATOM   6444  C CD2 . TYR C 2 151 ? 150.689 144.165 100.157 1.00 37.55  ? 126 TYR C CD2 1 
ATOM   6445  C CE1 . TYR C 2 151 ? 148.136 144.732 99.288  1.00 31.33  ? 126 TYR C CE1 1 
ATOM   6446  C CE2 . TYR C 2 151 ? 149.731 143.171 100.143 1.00 41.32  ? 126 TYR C CE2 1 
ATOM   6447  C CZ  . TYR C 2 151 ? 148.454 143.462 99.709  1.00 41.45  ? 126 TYR C CZ  1 
ATOM   6448  O OH  . TYR C 2 151 ? 147.493 142.478 99.694  1.00 50.78  ? 126 TYR C OH  1 
ATOM   6449  N N   . GLY C 2 152 ? 149.342 148.348 101.964 1.00 21.00  ? 127 GLY C N   1 
ATOM   6450  C CA  . GLY C 2 152 ? 148.804 148.422 103.313 1.00 18.31  ? 127 GLY C CA  1 
ATOM   6451  C C   . GLY C 2 152 ? 147.563 147.568 103.467 1.00 19.36  ? 127 GLY C C   1 
ATOM   6452  O O   . GLY C 2 152 ? 146.729 147.503 102.562 1.00 28.88  ? 127 GLY C O   1 
ATOM   6453  N N   . LEU C 2 153 ? 147.449 146.916 104.620 1.00 16.62  ? 128 LEU C N   1 
ATOM   6454  C CA  . LEU C 2 153 ? 146.299 146.093 104.956 1.00 14.70  ? 128 LEU C CA  1 
ATOM   6455  C C   . LEU C 2 153 ? 145.858 146.413 106.373 1.00 12.88  ? 128 LEU C C   1 
ATOM   6456  O O   . LEU C 2 153 ? 146.690 146.597 107.264 1.00 16.64  ? 128 LEU C O   1 
ATOM   6457  C CB  . LEU C 2 153 ? 146.611 144.594 104.841 1.00 15.84  ? 128 LEU C CB  1 
ATOM   6458  C CG  . LEU C 2 153 ? 146.878 144.035 103.444 1.00 20.32  ? 128 LEU C CG  1 
ATOM   6459  C CD1 . LEU C 2 153 ? 148.359 144.110 103.138 1.00 24.82  ? 128 LEU C CD1 1 
ATOM   6460  C CD2 . LEU C 2 153 ? 146.374 142.610 103.314 1.00 20.78  ? 128 LEU C CD2 1 
ATOM   6461  N N   . ARG C 2 154 ? 144.548 146.486 106.573 1.00 11.46  ? 129 ARG C N   1 
ATOM   6462  C CA  . ARG C 2 154 ? 143.964 146.639 107.899 1.00 12.53  ? 129 ARG C CA  1 
ATOM   6463  C C   . ARG C 2 154 ? 143.568 145.257 108.393 1.00 14.75  ? 129 ARG C C   1 
ATOM   6464  O O   . ARG C 2 154 ? 142.629 144.646 107.873 1.00 19.94  ? 129 ARG C O   1 
ATOM   6465  C CB  . ARG C 2 154 ? 142.758 147.571 107.871 1.00 18.17  ? 129 ARG C CB  1 
ATOM   6466  C CG  . ARG C 2 154 ? 142.176 147.843 109.241 1.00 21.53  ? 129 ARG C CG  1 
ATOM   6467  C CD  . ARG C 2 154 ? 141.299 149.072 109.239 1.00 23.70  ? 129 ARG C CD  1 
ATOM   6468  N NE  . ARG C 2 154 ? 140.555 149.185 110.485 1.00 23.40  ? 129 ARG C NE  1 
ATOM   6469  C CZ  . ARG C 2 154 ? 139.281 148.846 110.623 1.00 26.51  ? 129 ARG C CZ  1 
ATOM   6470  N NH1 . ARG C 2 154 ? 138.561 148.433 109.594 1.00 25.34  ? 129 ARG C NH1 1 
ATOM   6471  N NH2 . ARG C 2 154 ? 138.712 148.937 111.821 1.00 28.88  ? 129 ARG C NH2 1 
ATOM   6472  N N   . ILE C 2 155 ? 144.282 144.775 109.403 1.00 13.46  ? 130 ILE C N   1 
ATOM   6473  C CA  . ILE C 2 155 ? 144.225 143.388 109.836 1.00 14.87  ? 130 ILE C CA  1 
ATOM   6474  C C   . ILE C 2 155 ? 143.805 143.357 111.296 1.00 15.52  ? 130 ILE C C   1 
ATOM   6475  O O   . ILE C 2 155 ? 144.327 144.123 112.114 1.00 20.16  ? 130 ILE C O   1 
ATOM   6476  C CB  . ILE C 2 155 ? 145.580 142.680 109.645 1.00 13.84  ? 130 ILE C CB  1 
ATOM   6477  C CG1 . ILE C 2 155 ? 145.934 142.592 108.161 1.00 11.04  ? 130 ILE C CG1 1 
ATOM   6478  C CG2 . ILE C 2 155 ? 145.562 141.300 110.272 1.00 17.37  ? 130 ILE C CG2 1 
ATOM   6479  C CD1 . ILE C 2 155 ? 147.376 142.241 107.903 1.00 11.01  ? 130 ILE C CD1 1 
ATOM   6480  N N   . THR C 2 156 ? 142.860 142.483 111.618 1.00 16.15  ? 131 THR C N   1 
ATOM   6481  C CA  . THR C 2 156 ? 142.599 142.087 112.993 1.00 18.96  ? 131 THR C CA  1 
ATOM   6482  C C   . THR C 2 156 ? 143.106 140.662 113.129 1.00 19.28  ? 131 THR C C   1 
ATOM   6483  O O   . THR C 2 156 ? 142.666 139.772 112.395 1.00 22.12  ? 131 THR C O   1 
ATOM   6484  C CB  . THR C 2 156 ? 141.112 142.175 113.333 1.00 24.81  ? 131 THR C CB  1 
ATOM   6485  O OG1 . THR C 2 156 ? 140.696 143.547 113.322 1.00 26.38  ? 131 THR C OG1 1 
ATOM   6486  C CG2 . THR C 2 156 ? 140.844 141.580 114.706 1.00 21.48  ? 131 THR C CG2 1 
ATOM   6487  N N   . THR C 2 157 ? 144.020 140.446 114.068 1.00 21.31  ? 132 THR C N   1 
ATOM   6488  C CA  . THR C 2 157 ? 144.657 139.151 114.238 1.00 22.44  ? 132 THR C CA  1 
ATOM   6489  C C   . THR C 2 157 ? 144.661 138.728 115.697 1.00 21.79  ? 132 THR C C   1 
ATOM   6490  O O   . THR C 2 157 ? 144.880 139.546 116.595 1.00 25.68  ? 132 THR C O   1 
ATOM   6491  C CB  . THR C 2 157 ? 146.098 139.169 113.695 1.00 21.13  ? 132 THR C CB  1 
ATOM   6492  O OG1 . THR C 2 157 ? 146.721 137.902 113.933 1.00 19.36  ? 132 THR C OG1 1 
ATOM   6493  C CG2 . THR C 2 157 ? 146.918 140.274 114.346 1.00 18.41  ? 132 THR C CG2 1 
ATOM   6494  N N   . THR C 2 158 ? 144.395 137.448 115.922 1.00 20.12  ? 133 THR C N   1 
ATOM   6495  C CA  . THR C 2 158 ? 144.529 136.833 117.234 1.00 23.60  ? 133 THR C CA  1 
ATOM   6496  C C   . THR C 2 158 ? 145.843 136.065 117.218 1.00 25.47  ? 133 THR C C   1 
ATOM   6497  O O   . THR C 2 158 ? 145.971 135.057 116.517 1.00 25.73  ? 133 THR C O   1 
ATOM   6498  C CB  . THR C 2 158 ? 143.351 135.912 117.541 1.00 25.39  ? 133 THR C CB  1 
ATOM   6499  O OG1 . THR C 2 158 ? 142.129 136.657 117.475 1.00 32.89  ? 133 THR C OG1 1 
ATOM   6500  C CG2 . THR C 2 158 ? 143.497 135.308 118.926 1.00 26.35  ? 133 THR C CG2 1 
ATOM   6501  N N   . ALA C 2 159 ? 146.817 136.540 117.985 1.00 29.34  ? 134 ALA C N   1 
ATOM   6502  C CA  . ALA C 2 159 ? 148.161 135.987 117.966 1.00 26.33  ? 134 ALA C CA  1 
ATOM   6503  C C   . ALA C 2 159 ? 148.423 135.222 119.252 1.00 27.09  ? 134 ALA C C   1 
ATOM   6504  O O   . ALA C 2 159 ? 148.081 135.686 120.342 1.00 30.34  ? 134 ALA C O   1 
ATOM   6505  C CB  . ALA C 2 159 ? 149.207 137.090 117.792 1.00 22.86  ? 134 ALA C CB  1 
ATOM   6506  N N   . ALA C 2 160 ? 149.044 134.055 119.117 1.00 27.68  ? 135 ALA C N   1 
ATOM   6507  C CA  . ALA C 2 160 ? 149.342 133.232 120.277 1.00 27.27  ? 135 ALA C CA  1 
ATOM   6508  C C   . ALA C 2 160 ? 150.406 133.894 121.142 1.00 35.90  ? 135 ALA C C   1 
ATOM   6509  O O   . ALA C 2 160 ? 151.412 134.405 120.641 1.00 39.97  ? 135 ALA C O   1 
ATOM   6510  C CB  . ALA C 2 160 ? 149.805 131.845 119.839 1.00 25.68  ? 135 ALA C CB  1 
ATOM   6511  N N   . CYS C 2 161 ? 150.174 133.883 122.451 1.00 39.29  ? 136 CYS C N   1 
ATOM   6512  C CA  . CYS C 2 161 ? 151.099 134.466 123.422 1.00 44.67  ? 136 CYS C CA  1 
ATOM   6513  C C   . CYS C 2 161 ? 151.172 133.521 124.616 1.00 53.51  ? 136 CYS C C   1 
ATOM   6514  O O   . CYS C 2 161 ? 150.267 133.508 125.456 1.00 59.27  ? 136 CYS C O   1 
ATOM   6515  C CB  . CYS C 2 161 ? 150.662 135.863 123.852 1.00 41.09  ? 136 CYS C CB  1 
ATOM   6516  S SG  . CYS C 2 161 ? 151.761 136.615 125.084 1.00 74.10  ? 136 CYS C SG  1 
ATOM   6517  N N   . MET C 2 162 ? 152.238 132.728 124.687 1.00 52.93  ? 137 MET C N   1 
ATOM   6518  C CA  . MET C 2 162 ? 152.423 131.864 125.843 1.00 53.38  ? 137 MET C CA  1 
ATOM   6519  C C   . MET C 2 162 ? 152.707 132.733 127.056 1.00 52.91  ? 137 MET C C   1 
ATOM   6520  O O   . MET C 2 162 ? 153.655 133.524 127.057 1.00 51.36  ? 137 MET C O   1 
ATOM   6521  C CB  . MET C 2 162 ? 153.565 130.879 125.607 1.00 56.87  ? 137 MET C CB  1 
ATOM   6522  C CG  . MET C 2 162 ? 153.674 129.796 126.672 1.00 65.92  ? 137 MET C CG  1 
ATOM   6523  S SD  . MET C 2 162 ? 152.240 128.711 126.773 1.00 103.40 ? 137 MET C SD  1 
ATOM   6524  C CE  . MET C 2 162 ? 152.728 127.621 128.107 1.00 83.15  ? 137 MET C CE  1 
ATOM   6525  N N   . MET C 2 163 ? 151.887 132.584 128.087 1.00 49.55  ? 138 MET C N   1 
ATOM   6526  C CA  . MET C 2 163 ? 151.955 133.429 129.265 1.00 44.53  ? 138 MET C CA  1 
ATOM   6527  C C   . MET C 2 163 ? 152.359 132.612 130.480 1.00 43.43  ? 138 MET C C   1 
ATOM   6528  O O   . MET C 2 163 ? 151.917 131.471 130.652 1.00 45.21  ? 138 MET C O   1 
ATOM   6529  C CB  . MET C 2 163 ? 150.607 134.106 129.519 1.00 39.84  ? 138 MET C CB  1 
ATOM   6530  C CG  . MET C 2 163 ? 150.149 134.998 128.382 1.00 42.89  ? 138 MET C CG  1 
ATOM   6531  S SD  . MET C 2 163 ? 148.482 135.633 128.625 1.00 47.19  ? 138 MET C SD  1 
ATOM   6532  C CE  . MET C 2 163 ? 148.210 136.440 127.052 1.00 58.71  ? 138 MET C CE  1 
ATOM   6533  N N   . ASP C 2 164 ? 153.201 133.202 131.318 1.00 40.49  ? 139 ASP C N   1 
ATOM   6534  C CA  . ASP C 2 164 ? 153.600 132.602 132.583 1.00 41.52  ? 139 ASP C CA  1 
ATOM   6535  C C   . ASP C 2 164 ? 152.774 133.306 133.651 1.00 39.42  ? 139 ASP C C   1 
ATOM   6536  O O   . ASP C 2 164 ? 153.091 134.425 134.061 1.00 40.82  ? 139 ASP C O   1 
ATOM   6537  C CB  . ASP C 2 164 ? 155.099 132.752 132.819 1.00 48.45  ? 139 ASP C CB  1 
ATOM   6538  C CG  . ASP C 2 164 ? 155.555 132.097 134.107 1.00 53.35  ? 139 ASP C CG  1 
ATOM   6539  O OD1 . ASP C 2 164 ? 154.814 131.242 134.636 1.00 49.67  ? 139 ASP C OD1 1 
ATOM   6540  O OD2 . ASP C 2 164 ? 156.656 132.434 134.590 1.00 55.47  ? 139 ASP C OD2 1 
ATOM   6541  N N   . LEU C 2 165 ? 151.710 132.645 134.101 1.00 34.53  ? 140 LEU C N   1 
ATOM   6542  C CA  . LEU C 2 165 ? 150.742 133.246 135.004 1.00 29.46  ? 140 LEU C CA  1 
ATOM   6543  C C   . LEU C 2 165 ? 150.962 132.825 136.447 1.00 31.24  ? 140 LEU C C   1 
ATOM   6544  O O   . LEU C 2 165 ? 150.039 132.916 137.260 1.00 35.74  ? 140 LEU C O   1 
ATOM   6545  C CB  . LEU C 2 165 ? 149.322 132.901 134.557 1.00 25.31  ? 140 LEU C CB  1 
ATOM   6546  C CG  . LEU C 2 165 ? 148.985 133.332 133.129 1.00 30.79  ? 140 LEU C CG  1 
ATOM   6547  C CD1 . LEU C 2 165 ? 147.747 132.626 132.623 1.00 31.19  ? 140 LEU C CD1 1 
ATOM   6548  C CD2 . LEU C 2 165 ? 148.795 134.837 133.070 1.00 33.83  ? 140 LEU C CD2 1 
ATOM   6549  N N   . ARG C 2 166 ? 152.169 132.369 136.781 1.00 32.15  ? 141 ARG C N   1 
ATOM   6550  C CA  . ARG C 2 166 ? 152.461 131.991 138.158 1.00 27.72  ? 141 ARG C CA  1 
ATOM   6551  C C   . ARG C 2 166 ? 152.338 133.186 139.092 1.00 26.42  ? 141 ARG C C   1 
ATOM   6552  O O   . ARG C 2 166 ? 151.848 133.056 140.219 1.00 29.61  ? 141 ARG C O   1 
ATOM   6553  C CB  . ARG C 2 166 ? 153.861 131.388 138.252 1.00 37.95  ? 141 ARG C CB  1 
ATOM   6554  C CG  . ARG C 2 166 ? 154.011 130.042 137.575 1.00 46.52  ? 141 ARG C CG  1 
ATOM   6555  C CD  . ARG C 2 166 ? 155.261 129.335 138.064 1.00 62.43  ? 141 ARG C CD  1 
ATOM   6556  N NE  . ARG C 2 166 ? 155.625 128.212 137.210 1.00 78.37  ? 141 ARG C NE  1 
ATOM   6557  C CZ  . ARG C 2 166 ? 156.483 128.289 136.202 1.00 75.54  ? 141 ARG C CZ  1 
ATOM   6558  N NH1 . ARG C 2 166 ? 157.088 129.425 135.896 1.00 62.21  ? 141 ARG C NH1 1 
ATOM   6559  N NH2 . ARG C 2 166 ? 156.743 127.199 135.486 1.00 86.47  ? 141 ARG C NH2 1 
ATOM   6560  N N   . ARG C 2 167 ? 152.784 134.357 138.644 1.00 23.74  ? 142 ARG C N   1 
ATOM   6561  C CA  . ARG C 2 167 ? 152.724 135.573 139.438 1.00 24.74  ? 142 ARG C CA  1 
ATOM   6562  C C   . ARG C 2 167 ? 151.422 136.348 139.253 1.00 27.39  ? 142 ARG C C   1 
ATOM   6563  O O   . ARG C 2 167 ? 151.296 137.450 139.793 1.00 30.76  ? 142 ARG C O   1 
ATOM   6564  C CB  . ARG C 2 167 ? 153.909 136.463 139.062 1.00 25.65  ? 142 ARG C CB  1 
ATOM   6565  C CG  . ARG C 2 167 ? 155.252 135.774 139.228 1.00 31.81  ? 142 ARG C CG  1 
ATOM   6566  C CD  . ARG C 2 167 ? 156.394 136.631 138.716 1.00 41.38  ? 142 ARG C CD  1 
ATOM   6567  N NE  . ARG C 2 167 ? 156.827 137.654 139.658 1.00 46.00  ? 142 ARG C NE  1 
ATOM   6568  C CZ  . ARG C 2 167 ? 157.734 137.456 140.604 1.00 52.94  ? 142 ARG C CZ  1 
ATOM   6569  N NH1 . ARG C 2 167 ? 158.294 136.272 140.787 1.00 48.27  ? 142 ARG C NH1 1 
ATOM   6570  N NH2 . ARG C 2 167 ? 158.100 138.476 141.374 1.00 57.01  ? 142 ARG C NH2 1 
ATOM   6571  N N   . TYR C 2 168 ? 150.465 135.803 138.507 1.00 22.82  ? 143 TYR C N   1 
ATOM   6572  C CA  . TYR C 2 168 ? 149.169 136.448 138.334 1.00 18.91  ? 143 TYR C CA  1 
ATOM   6573  C C   . TYR C 2 168 ? 148.517 136.716 139.690 1.00 21.95  ? 143 TYR C C   1 
ATOM   6574  O O   . TYR C 2 168 ? 148.485 135.826 140.545 1.00 28.13  ? 143 TYR C O   1 
ATOM   6575  C CB  . TYR C 2 168 ? 148.259 135.572 137.472 1.00 20.43  ? 143 TYR C CB  1 
ATOM   6576  C CG  . TYR C 2 168 ? 146.859 136.104 137.280 1.00 22.50  ? 143 TYR C CG  1 
ATOM   6577  C CD1 . TYR C 2 168 ? 146.581 137.026 136.283 1.00 23.62  ? 143 TYR C CD1 1 
ATOM   6578  C CD2 . TYR C 2 168 ? 145.811 135.672 138.081 1.00 20.83  ? 143 TYR C CD2 1 
ATOM   6579  C CE1 . TYR C 2 168 ? 145.304 137.510 136.095 1.00 23.34  ? 143 TYR C CE1 1 
ATOM   6580  C CE2 . TYR C 2 168 ? 144.531 136.153 137.901 1.00 20.49  ? 143 TYR C CE2 1 
ATOM   6581  C CZ  . TYR C 2 168 ? 144.285 137.071 136.905 1.00 21.33  ? 143 TYR C CZ  1 
ATOM   6582  O OH  . TYR C 2 168 ? 143.014 137.558 136.716 1.00 26.35  ? 143 TYR C OH  1 
ATOM   6583  N N   . PRO C 2 169 ? 147.949 137.914 139.914 1.00 20.33  ? 144 PRO C N   1 
ATOM   6584  C CA  . PRO C 2 169 ? 147.752 139.035 138.989 1.00 21.32  ? 144 PRO C CA  1 
ATOM   6585  C C   . PRO C 2 169 ? 148.916 140.022 138.970 1.00 22.93  ? 144 PRO C C   1 
ATOM   6586  O O   . PRO C 2 169 ? 148.830 141.071 138.340 1.00 25.35  ? 144 PRO C O   1 
ATOM   6587  C CB  . PRO C 2 169 ? 146.475 139.677 139.534 1.00 20.60  ? 144 PRO C CB  1 
ATOM   6588  C CG  . PRO C 2 169 ? 146.626 139.525 141.018 1.00 16.52  ? 144 PRO C CG  1 
ATOM   6589  C CD  . PRO C 2 169 ? 147.337 138.200 141.225 1.00 19.26  ? 144 PRO C CD  1 
ATOM   6590  N N   . LEU C 2 170 ? 150.021 139.709 139.647 1.00 24.09  ? 145 LEU C N   1 
ATOM   6591  C CA  . LEU C 2 170 ? 151.200 140.567 139.675 1.00 22.26  ? 145 LEU C CA  1 
ATOM   6592  C C   . LEU C 2 170 ? 152.196 140.205 138.587 1.00 25.42  ? 145 LEU C C   1 
ATOM   6593  O O   . LEU C 2 170 ? 153.407 140.384 138.769 1.00 29.00  ? 145 LEU C O   1 
ATOM   6594  C CB  . LEU C 2 170 ? 151.875 140.501 141.046 1.00 25.61  ? 145 LEU C CB  1 
ATOM   6595  C CG  . LEU C 2 170 ? 151.151 141.035 142.284 1.00 25.39  ? 145 LEU C CG  1 
ATOM   6596  C CD1 . LEU C 2 170 ? 150.124 140.047 142.812 1.00 24.50  ? 145 LEU C CD1 1 
ATOM   6597  C CD2 . LEU C 2 170 ? 152.157 141.381 143.360 1.00 35.19  ? 145 LEU C CD2 1 
ATOM   6598  N N   . ASP C 2 171 ? 151.713 139.700 137.461 1.00 25.22  ? 146 ASP C N   1 
ATOM   6599  C CA  . ASP C 2 171 ? 152.556 139.172 136.405 1.00 25.56  ? 146 ASP C CA  1 
ATOM   6600  C C   . ASP C 2 171 ? 152.852 140.233 135.358 1.00 28.57  ? 146 ASP C C   1 
ATOM   6601  O O   . ASP C 2 171 ? 152.146 141.235 135.228 1.00 32.58  ? 146 ASP C O   1 
ATOM   6602  C CB  . ASP C 2 171 ? 151.887 137.980 135.724 1.00 26.71  ? 146 ASP C CB  1 
ATOM   6603  C CG  . ASP C 2 171 ? 150.508 138.317 135.194 1.00 30.41  ? 146 ASP C CG  1 
ATOM   6604  O OD1 . ASP C 2 171 ? 149.788 139.089 135.859 1.00 30.63  ? 146 ASP C OD1 1 
ATOM   6605  O OD2 . ASP C 2 171 ? 150.148 137.820 134.107 1.00 32.69  ? 146 ASP C OD2 1 
ATOM   6606  N N   . GLU C 2 172 ? 153.922 139.995 134.608 1.00 33.47  ? 147 GLU C N   1 
ATOM   6607  C CA  . GLU C 2 172 ? 154.326 140.861 133.512 1.00 34.00  ? 147 GLU C CA  1 
ATOM   6608  C C   . GLU C 2 172 ? 154.495 139.960 132.303 1.00 35.35  ? 147 GLU C C   1 
ATOM   6609  O O   . GLU C 2 172 ? 155.266 138.996 132.347 1.00 43.78  ? 147 GLU C O   1 
ATOM   6610  C CB  . GLU C 2 172 ? 155.629 141.600 133.826 1.00 32.46  ? 147 GLU C CB  1 
ATOM   6611  C CG  . GLU C 2 172 ? 155.815 142.892 133.055 1.00 36.54  ? 147 GLU C CG  1 
ATOM   6612  C CD  . GLU C 2 172 ? 157.089 143.616 133.438 1.00 48.26  ? 147 GLU C CD  1 
ATOM   6613  O OE1 . GLU C 2 172 ? 158.126 142.943 133.612 1.00 47.94  ? 147 GLU C OE1 1 
ATOM   6614  O OE2 . GLU C 2 172 ? 157.054 144.858 133.564 1.00 51.99  ? 147 GLU C OE2 1 
ATOM   6615  N N   . GLN C 2 173 ? 153.782 140.274 131.231 1.00 27.00  ? 148 GLN C N   1 
ATOM   6616  C CA  . GLN C 2 173 ? 153.721 139.411 130.066 1.00 26.14  ? 148 GLN C CA  1 
ATOM   6617  C C   . GLN C 2 173 ? 154.471 140.035 128.903 1.00 26.55  ? 148 GLN C C   1 
ATOM   6618  O O   . GLN C 2 173 ? 154.605 141.257 128.810 1.00 30.61  ? 148 GLN C O   1 
ATOM   6619  C CB  . GLN C 2 173 ? 152.272 139.139 129.654 1.00 27.72  ? 148 GLN C CB  1 
ATOM   6620  C CG  . GLN C 2 173 ? 151.398 138.576 130.758 1.00 32.26  ? 148 GLN C CG  1 
ATOM   6621  C CD  . GLN C 2 173 ? 151.908 137.252 131.284 1.00 37.82  ? 148 GLN C CD  1 
ATOM   6622  O OE1 . GLN C 2 173 ? 152.487 136.459 130.543 1.00 41.62  ? 148 GLN C OE1 1 
ATOM   6623  N NE2 . GLN C 2 173 ? 151.685 136.999 132.566 1.00 37.15  ? 148 GLN C NE2 1 
ATOM   6624  N N   . ASN C 2 174 ? 154.961 139.176 128.018 1.00 26.44  ? 149 ASN C N   1 
ATOM   6625  C CA  . ASN C 2 174 ? 155.725 139.602 126.851 1.00 27.74  ? 149 ASN C CA  1 
ATOM   6626  C C   . ASN C 2 174 ? 155.067 138.894 125.674 1.00 31.58  ? 149 ASN C C   1 
ATOM   6627  O O   . ASN C 2 174 ? 155.336 137.718 125.416 1.00 37.48  ? 149 ASN C O   1 
ATOM   6628  C CB  . ASN C 2 174 ? 157.204 139.244 126.997 1.00 30.22  ? 149 ASN C CB  1 
ATOM   6629  C CG  . ASN C 2 174 ? 158.000 139.426 125.710 1.00 34.42  ? 149 ASN C CG  1 
ATOM   6630  O OD1 . ASN C 2 174 ? 157.491 139.910 124.700 1.00 37.15  ? 149 ASN C OD1 1 
ATOM   6631  N ND2 . ASN C 2 174 ? 159.268 139.032 125.751 1.00 45.03  ? 149 ASN C ND2 1 
ATOM   6632  N N   . CYS C 2 175 ? 154.209 139.616 124.962 1.00 29.09  ? 150 CYS C N   1 
ATOM   6633  C CA  . CYS C 2 175 ? 153.462 139.071 123.840 1.00 30.30  ? 150 CYS C CA  1 
ATOM   6634  C C   . CYS C 2 175 ? 154.053 139.632 122.560 1.00 29.22  ? 150 CYS C C   1 
ATOM   6635  O O   . CYS C 2 175 ? 154.252 140.845 122.442 1.00 33.08  ? 150 CYS C O   1 
ATOM   6636  C CB  . CYS C 2 175 ? 151.970 139.393 123.937 1.00 39.66  ? 150 CYS C CB  1 
ATOM   6637  S SG  . CYS C 2 175 ? 151.130 138.538 125.284 1.00 67.21  ? 150 CYS C SG  1 
ATOM   6638  N N   . THR C 2 176 ? 154.322 138.753 121.609 1.00 28.44  ? 151 THR C N   1 
ATOM   6639  C CA  . THR C 2 176 ? 155.039 139.118 120.404 1.00 26.74  ? 151 THR C CA  1 
ATOM   6640  C C   . THR C 2 176 ? 154.167 138.876 119.182 1.00 27.60  ? 151 THR C C   1 
ATOM   6641  O O   . THR C 2 176 ? 153.130 138.212 119.240 1.00 35.71  ? 151 THR C O   1 
ATOM   6642  C CB  . THR C 2 176 ? 156.349 138.330 120.273 1.00 27.33  ? 151 THR C CB  1 
ATOM   6643  O OG1 . THR C 2 176 ? 156.063 136.997 119.834 1.00 34.81  ? 151 THR C OG1 1 
ATOM   6644  C CG2 . THR C 2 176 ? 157.074 138.267 121.606 1.00 30.58  ? 151 THR C CG2 1 
ATOM   6645  N N   . LEU C 2 177 ? 154.611 139.446 118.070 1.00 24.05  ? 152 LEU C N   1 
ATOM   6646  C CA  . LEU C 2 177 ? 154.073 139.144 116.754 1.00 25.88  ? 152 LEU C CA  1 
ATOM   6647  C C   . LEU C 2 177 ? 155.268 138.796 115.887 1.00 26.43  ? 152 LEU C C   1 
ATOM   6648  O O   . LEU C 2 177 ? 156.184 139.610 115.735 1.00 30.41  ? 152 LEU C O   1 
ATOM   6649  C CB  . LEU C 2 177 ? 153.296 140.330 116.178 1.00 23.60  ? 152 LEU C CB  1 
ATOM   6650  C CG  . LEU C 2 177 ? 152.641 140.151 114.808 1.00 21.10  ? 152 LEU C CG  1 
ATOM   6651  C CD1 . LEU C 2 177 ? 151.598 139.047 114.848 1.00 20.61  ? 152 LEU C CD1 1 
ATOM   6652  C CD2 . LEU C 2 177 ? 152.023 141.456 114.342 1.00 19.86  ? 152 LEU C CD2 1 
ATOM   6653  N N   . GLU C 2 178 ? 155.257 137.601 115.315 1.00 25.12  ? 153 GLU C N   1 
ATOM   6654  C CA  . GLU C 2 178 ? 156.372 137.117 114.520 1.00 24.56  ? 153 GLU C CA  1 
ATOM   6655  C C   . GLU C 2 178 ? 156.030 137.235 113.047 1.00 24.52  ? 153 GLU C C   1 
ATOM   6656  O O   . GLU C 2 178 ? 155.004 136.716 112.599 1.00 28.55  ? 153 GLU C O   1 
ATOM   6657  C CB  . GLU C 2 178 ? 156.697 135.662 114.858 1.00 28.33  ? 153 GLU C CB  1 
ATOM   6658  C CG  . GLU C 2 178 ? 156.879 135.368 116.335 1.00 30.87  ? 153 GLU C CG  1 
ATOM   6659  C CD  . GLU C 2 178 ? 158.024 136.142 116.946 1.00 32.55  ? 153 GLU C CD  1 
ATOM   6660  O OE1 . GLU C 2 178 ? 159.063 136.301 116.272 1.00 32.26  ? 153 GLU C OE1 1 
ATOM   6661  O OE2 . GLU C 2 178 ? 157.892 136.581 118.105 1.00 36.28  ? 153 GLU C OE2 1 
ATOM   6662  N N   . ILE C 2 179 ? 156.892 137.911 112.299 1.00 19.84  ? 154 ILE C N   1 
ATOM   6663  C CA  . ILE C 2 179 ? 156.678 138.147 110.881 1.00 23.31  ? 154 ILE C CA  1 
ATOM   6664  C C   . ILE C 2 179 ? 157.773 137.411 110.129 1.00 26.59  ? 154 ILE C C   1 
ATOM   6665  O O   . ILE C 2 179 ? 158.961 137.578 110.426 1.00 36.60  ? 154 ILE C O   1 
ATOM   6666  C CB  . ILE C 2 179 ? 156.693 139.654 110.569 1.00 22.78  ? 154 ILE C CB  1 
ATOM   6667  C CG1 . ILE C 2 179 ? 155.773 140.405 111.533 1.00 17.77  ? 154 ILE C CG1 1 
ATOM   6668  C CG2 . ILE C 2 179 ? 156.304 139.912 109.144 1.00 25.96  ? 154 ILE C CG2 1 
ATOM   6669  C CD1 . ILE C 2 179 ? 156.012 141.893 111.570 1.00 21.46  ? 154 ILE C CD1 1 
ATOM   6670  N N   . GLU C 2 180 ? 157.373 136.600 109.154 1.00 24.06  ? 155 GLU C N   1 
ATOM   6671  C CA  . GLU C 2 180 ? 158.313 135.735 108.463 1.00 28.40  ? 155 GLU C CA  1 
ATOM   6672  C C   . GLU C 2 180 ? 157.855 135.571 107.023 1.00 35.25  ? 155 GLU C C   1 
ATOM   6673  O O   . GLU C 2 180 ? 156.689 135.801 106.696 1.00 39.37  ? 155 GLU C O   1 
ATOM   6674  C CB  . GLU C 2 180 ? 158.422 134.377 109.171 1.00 29.66  ? 155 GLU C CB  1 
ATOM   6675  C CG  . GLU C 2 180 ? 159.551 133.484 108.694 1.00 41.69  ? 155 GLU C CG  1 
ATOM   6676  C CD  . GLU C 2 180 ? 160.001 132.504 109.757 1.00 50.60  ? 155 GLU C CD  1 
ATOM   6677  O OE1 . GLU C 2 180 ? 160.281 132.941 110.892 1.00 50.40  ? 155 GLU C OE1 1 
ATOM   6678  O OE2 . GLU C 2 180 ? 160.076 131.295 109.457 1.00 60.06  ? 155 GLU C OE2 1 
ATOM   6679  N N   . SER C 2 181 ? 158.780 135.158 106.163 1.00 38.11  ? 156 SER C N   1 
ATOM   6680  C CA  . SER C 2 181 ? 158.425 134.765 104.810 1.00 42.10  ? 156 SER C CA  1 
ATOM   6681  C C   . SER C 2 181 ? 158.100 133.280 104.819 1.00 50.21  ? 156 SER C C   1 
ATOM   6682  O O   . SER C 2 181 ? 158.744 132.500 105.526 1.00 54.72  ? 156 SER C O   1 
ATOM   6683  C CB  . SER C 2 181 ? 159.566 135.057 103.836 1.00 46.03  ? 156 SER C CB  1 
ATOM   6684  O OG  . SER C 2 181 ? 159.178 134.785 102.502 1.00 57.84  ? 156 SER C OG  1 
ATOM   6685  N N   . TYR C 2 182 ? 157.101 132.885 104.033 1.00 50.76  ? 157 TYR C N   1 
ATOM   6686  C CA  . TYR C 2 182 ? 156.698 131.485 104.067 1.00 47.28  ? 157 TYR C CA  1 
ATOM   6687  C C   . TYR C 2 182 ? 157.613 130.614 103.217 1.00 50.77  ? 157 TYR C C   1 
ATOM   6688  O O   . TYR C 2 182 ? 158.180 129.632 103.708 1.00 61.42  ? 157 TYR C O   1 
ATOM   6689  C CB  . TYR C 2 182 ? 155.245 131.325 103.622 1.00 41.95  ? 157 TYR C CB  1 
ATOM   6690  C CG  . TYR C 2 182 ? 154.684 129.979 104.016 1.00 46.14  ? 157 TYR C CG  1 
ATOM   6691  C CD1 . TYR C 2 182 ? 154.186 129.766 105.293 1.00 43.77  ? 157 TYR C CD1 1 
ATOM   6692  C CD2 . TYR C 2 182 ? 154.686 128.914 103.129 1.00 46.48  ? 157 TYR C CD2 1 
ATOM   6693  C CE1 . TYR C 2 182 ? 153.686 128.541 105.669 1.00 34.61  ? 157 TYR C CE1 1 
ATOM   6694  C CE2 . TYR C 2 182 ? 154.187 127.682 103.499 1.00 40.67  ? 157 TYR C CE2 1 
ATOM   6695  C CZ  . TYR C 2 182 ? 153.689 127.503 104.769 1.00 38.39  ? 157 TYR C CZ  1 
ATOM   6696  O OH  . TYR C 2 182 ? 153.191 126.278 105.143 1.00 58.77  ? 157 TYR C OH  1 
ATOM   6697  N N   . GLY C 2 183 ? 157.778 130.961 101.945 1.00 52.45  ? 158 GLY C N   1 
ATOM   6698  C CA  . GLY C 2 183 ? 158.513 130.108 101.034 1.00 58.69  ? 158 GLY C CA  1 
ATOM   6699  C C   . GLY C 2 183 ? 159.670 130.775 100.323 1.00 63.98  ? 158 GLY C C   1 
ATOM   6700  O O   . GLY C 2 183 ? 159.994 130.418 99.188  1.00 67.33  ? 158 GLY C O   1 
ATOM   6701  N N   . TYR C 2 184 ? 160.301 131.746 100.975 1.00 61.07  ? 159 TYR C N   1 
ATOM   6702  C CA  . TYR C 2 184 ? 161.472 132.411 100.429 1.00 61.93  ? 159 TYR C CA  1 
ATOM   6703  C C   . TYR C 2 184 ? 162.564 132.452 101.486 1.00 68.14  ? 159 TYR C C   1 
ATOM   6704  O O   . TYR C 2 184 ? 162.290 132.565 102.684 1.00 67.99  ? 159 TYR C O   1 
ATOM   6705  C CB  . TYR C 2 184 ? 161.149 133.830 99.951  1.00 58.77  ? 159 TYR C CB  1 
ATOM   6706  C CG  . TYR C 2 184 ? 160.300 133.881 98.703  1.00 59.33  ? 159 TYR C CG  1 
ATOM   6707  C CD1 . TYR C 2 184 ? 160.733 133.295 97.523  1.00 64.14  ? 159 TYR C CD1 1 
ATOM   6708  C CD2 . TYR C 2 184 ? 159.070 134.520 98.702  1.00 56.46  ? 159 TYR C CD2 1 
ATOM   6709  C CE1 . TYR C 2 184 ? 159.962 133.339 96.379  1.00 66.30  ? 159 TYR C CE1 1 
ATOM   6710  C CE2 . TYR C 2 184 ? 158.291 134.570 97.564  1.00 57.59  ? 159 TYR C CE2 1 
ATOM   6711  C CZ  . TYR C 2 184 ? 158.743 133.978 96.406  1.00 64.46  ? 159 TYR C CZ  1 
ATOM   6712  O OH  . TYR C 2 184 ? 157.974 134.025 95.266  1.00 77.60  ? 159 TYR C OH  1 
ATOM   6713  N N   . THR C 2 185 ? 163.808 132.361 101.029 1.00 72.52  ? 160 THR C N   1 
ATOM   6714  C CA  . THR C 2 185 ? 164.969 132.491 101.890 1.00 76.06  ? 160 THR C CA  1 
ATOM   6715  C C   . THR C 2 185 ? 165.628 133.852 101.685 1.00 78.54  ? 160 THR C C   1 
ATOM   6716  O O   . THR C 2 185 ? 165.221 134.651 100.838 1.00 77.34  ? 160 THR C O   1 
ATOM   6717  C CB  . THR C 2 185 ? 165.961 131.358 101.622 1.00 75.02  ? 160 THR C CB  1 
ATOM   6718  O OG1 . THR C 2 185 ? 166.384 131.404 100.254 1.00 74.15  ? 160 THR C OG1 1 
ATOM   6719  C CG2 . THR C 2 185 ? 165.315 130.011 101.903 1.00 76.51  ? 160 THR C CG2 1 
ATOM   6720  N N   . THR C 2 186 ? 166.672 134.114 102.476 1.00 80.03  ? 161 THR C N   1 
ATOM   6721  C CA  . THR C 2 186 ? 167.365 135.393 102.400 1.00 80.23  ? 161 THR C CA  1 
ATOM   6722  C C   . THR C 2 186 ? 168.104 135.580 101.083 1.00 81.37  ? 161 THR C C   1 
ATOM   6723  O O   . THR C 2 186 ? 168.583 136.686 100.815 1.00 78.10  ? 161 THR C O   1 
ATOM   6724  C CB  . THR C 2 186 ? 168.345 135.533 103.564 1.00 75.09  ? 161 THR C CB  1 
ATOM   6725  O OG1 . THR C 2 186 ? 169.216 134.395 103.597 1.00 84.25  ? 161 THR C OG1 1 
ATOM   6726  C CG2 . THR C 2 186 ? 167.591 135.626 104.881 1.00 68.74  ? 161 THR C CG2 1 
ATOM   6727  N N   . ASP C 2 187 ? 168.210 134.535 100.264 1.00 86.35  ? 162 ASP C N   1 
ATOM   6728  C CA  . ASP C 2 187 ? 168.738 134.678 98.916  1.00 87.72  ? 162 ASP C CA  1 
ATOM   6729  C C   . ASP C 2 187 ? 167.737 135.320 97.967  1.00 86.45  ? 162 ASP C C   1 
ATOM   6730  O O   . ASP C 2 187 ? 168.118 135.698 96.854  1.00 91.85  ? 162 ASP C O   1 
ATOM   6731  C CB  . ASP C 2 187 ? 169.161 133.314 98.365  1.00 90.06  ? 162 ASP C CB  1 
ATOM   6732  C CG  . ASP C 2 187 ? 170.190 132.627 99.238  1.00 97.08  ? 162 ASP C CG  1 
ATOM   6733  O OD1 . ASP C 2 187 ? 171.077 133.323 99.775  1.00 99.67  ? 162 ASP C OD1 1 
ATOM   6734  O OD2 . ASP C 2 187 ? 170.114 131.390 99.386  1.00 95.85  ? 162 ASP C OD2 1 
ATOM   6735  N N   . ASP C 2 188 ? 166.479 135.455 98.378  1.00 79.90  ? 163 ASP C N   1 
ATOM   6736  C CA  . ASP C 2 188 ? 165.431 136.004 97.528  1.00 81.55  ? 163 ASP C CA  1 
ATOM   6737  C C   . ASP C 2 188 ? 164.745 137.221 98.125  1.00 77.51  ? 163 ASP C C   1 
ATOM   6738  O O   . ASP C 2 188 ? 164.399 138.144 97.385  1.00 76.87  ? 163 ASP C O   1 
ATOM   6739  C CB  . ASP C 2 188 ? 164.375 134.930 97.226  1.00 86.54  ? 163 ASP C CB  1 
ATOM   6740  C CG  . ASP C 2 188 ? 164.985 133.636 96.727  1.00 91.29  ? 163 ASP C CG  1 
ATOM   6741  O OD1 . ASP C 2 188 ? 166.006 133.694 96.010  1.00 95.58  ? 163 ASP C OD1 1 
ATOM   6742  O OD2 . ASP C 2 188 ? 164.440 132.559 97.049  1.00 87.70  ? 163 ASP C OD2 1 
ATOM   6743  N N   . ILE C 2 189 ? 164.527 137.252 99.438  1.00 71.42  ? 164 ILE C N   1 
ATOM   6744  C CA  . ILE C 2 189 ? 163.785 138.335 100.073 1.00 68.62  ? 164 ILE C CA  1 
ATOM   6745  C C   . ILE C 2 189 ? 164.443 138.662 101.408 1.00 64.56  ? 164 ILE C C   1 
ATOM   6746  O O   . ILE C 2 189 ? 164.925 137.770 102.113 1.00 65.81  ? 164 ILE C O   1 
ATOM   6747  C CB  . ILE C 2 189 ? 162.293 137.979 100.249 1.00 58.41  ? 164 ILE C CB  1 
ATOM   6748  C CG1 . ILE C 2 189 ? 161.482 139.219 100.618 1.00 54.49  ? 164 ILE C CG1 1 
ATOM   6749  C CG2 . ILE C 2 189 ? 162.109 136.922 101.318 1.00 61.88  ? 164 ILE C CG2 1 
ATOM   6750  C CD1 . ILE C 2 189 ? 159.989 138.994 100.572 1.00 53.08  ? 164 ILE C CD1 1 
ATOM   6751  N N   . GLU C 2 190 ? 164.496 139.951 101.735 1.00 65.50  ? 165 GLU C N   1 
ATOM   6752  C CA  . GLU C 2 190 ? 165.014 140.427 103.010 1.00 59.23  ? 165 GLU C CA  1 
ATOM   6753  C C   . GLU C 2 190 ? 163.979 141.326 103.669 1.00 54.80  ? 165 GLU C C   1 
ATOM   6754  O O   . GLU C 2 190 ? 163.290 142.091 102.989 1.00 63.23  ? 165 GLU C O   1 
ATOM   6755  C CB  . GLU C 2 190 ? 166.336 141.180 102.827 1.00 68.02  ? 165 GLU C CB  1 
ATOM   6756  C CG  . GLU C 2 190 ? 167.447 140.326 102.235 1.00 77.37  ? 165 GLU C CG  1 
ATOM   6757  C CD  . GLU C 2 190 ? 168.724 141.108 101.994 1.00 89.82  ? 165 GLU C CD  1 
ATOM   6758  O OE1 . GLU C 2 190 ? 168.684 142.354 102.065 1.00 86.94  ? 165 GLU C OE1 1 
ATOM   6759  O OE2 . GLU C 2 190 ? 169.768 140.475 101.733 1.00 97.74  ? 165 GLU C OE2 1 
ATOM   6760  N N   . PHE C 2 191 ? 163.875 141.240 104.991 1.00 43.73  ? 166 PHE C N   1 
ATOM   6761  C CA  . PHE C 2 191 ? 162.956 142.070 105.753 1.00 41.76  ? 166 PHE C CA  1 
ATOM   6762  C C   . PHE C 2 191 ? 163.731 143.074 106.597 1.00 38.54  ? 166 PHE C C   1 
ATOM   6763  O O   . PHE C 2 191 ? 164.817 142.777 107.100 1.00 48.42  ? 166 PHE C O   1 
ATOM   6764  C CB  . PHE C 2 191 ? 162.074 141.219 106.671 1.00 43.74  ? 166 PHE C CB  1 
ATOM   6765  C CG  . PHE C 2 191 ? 161.031 140.411 105.952 1.00 41.44  ? 166 PHE C CG  1 
ATOM   6766  C CD1 . PHE C 2 191 ? 160.802 140.583 104.601 1.00 44.71  ? 166 PHE C CD1 1 
ATOM   6767  C CD2 . PHE C 2 191 ? 160.271 139.481 106.640 1.00 31.91  ? 166 PHE C CD2 1 
ATOM   6768  C CE1 . PHE C 2 191 ? 159.842 139.839 103.949 1.00 45.92  ? 166 PHE C CE1 1 
ATOM   6769  C CE2 . PHE C 2 191 ? 159.311 138.737 105.994 1.00 33.19  ? 166 PHE C CE2 1 
ATOM   6770  C CZ  . PHE C 2 191 ? 159.096 138.915 104.646 1.00 39.68  ? 166 PHE C CZ  1 
ATOM   6771  N N   . TYR C 2 192 ? 163.157 144.265 106.756 1.00 37.74  ? 167 TYR C N   1 
ATOM   6772  C CA  . TYR C 2 192 ? 163.676 145.240 107.704 1.00 37.34  ? 167 TYR C CA  1 
ATOM   6773  C C   . TYR C 2 192 ? 162.549 146.157 108.155 1.00 39.70  ? 167 TYR C C   1 
ATOM   6774  O O   . TYR C 2 192 ? 161.533 146.310 107.474 1.00 47.38  ? 167 TYR C O   1 
ATOM   6775  C CB  . TYR C 2 192 ? 164.821 146.067 107.104 1.00 35.99  ? 167 TYR C CB  1 
ATOM   6776  C CG  . TYR C 2 192 ? 164.415 146.932 105.932 1.00 42.68  ? 167 TYR C CG  1 
ATOM   6777  C CD1 . TYR C 2 192 ? 164.378 146.417 104.643 1.00 51.40  ? 167 TYR C CD1 1 
ATOM   6778  C CD2 . TYR C 2 192 ? 164.072 148.265 106.114 1.00 41.35  ? 167 TYR C CD2 1 
ATOM   6779  C CE1 . TYR C 2 192 ? 164.007 147.205 103.570 1.00 59.15  ? 167 TYR C CE1 1 
ATOM   6780  C CE2 . TYR C 2 192 ? 163.701 149.060 105.047 1.00 47.65  ? 167 TYR C CE2 1 
ATOM   6781  C CZ  . TYR C 2 192 ? 163.671 148.525 103.777 1.00 57.19  ? 167 TYR C CZ  1 
ATOM   6782  O OH  . TYR C 2 192 ? 163.302 149.311 102.710 1.00 54.25  ? 167 TYR C OH  1 
ATOM   6783  N N   . TRP C 2 193 ? 162.745 146.766 109.322 1.00 31.43  ? 168 TRP C N   1 
ATOM   6784  C CA  . TRP C 2 193 ? 161.817 147.758 109.857 1.00 29.59  ? 168 TRP C CA  1 
ATOM   6785  C C   . TRP C 2 193 ? 162.082 149.107 109.199 1.00 38.37  ? 168 TRP C C   1 
ATOM   6786  O O   . TRP C 2 193 ? 163.097 149.752 109.475 1.00 42.45  ? 168 TRP C O   1 
ATOM   6787  C CB  . TRP C 2 193 ? 161.943 147.848 111.373 1.00 28.90  ? 168 TRP C CB  1 
ATOM   6788  C CG  . TRP C 2 193 ? 161.395 146.657 112.082 1.00 31.10  ? 168 TRP C CG  1 
ATOM   6789  C CD1 . TRP C 2 193 ? 162.098 145.707 112.758 1.00 32.42  ? 168 TRP C CD1 1 
ATOM   6790  C CD2 . TRP C 2 193 ? 160.015 146.299 112.205 1.00 31.74  ? 168 TRP C CD2 1 
ATOM   6791  N NE1 . TRP C 2 193 ? 161.242 144.772 113.286 1.00 31.07  ? 168 TRP C NE1 1 
ATOM   6792  C CE2 . TRP C 2 193 ? 159.956 145.115 112.961 1.00 30.01  ? 168 TRP C CE2 1 
ATOM   6793  C CE3 . TRP C 2 193 ? 158.822 146.864 111.744 1.00 29.17  ? 168 TRP C CE3 1 
ATOM   6794  C CZ2 . TRP C 2 193 ? 158.754 144.485 113.267 1.00 26.49  ? 168 TRP C CZ2 1 
ATOM   6795  C CZ3 . TRP C 2 193 ? 157.631 146.238 112.049 1.00 25.03  ? 168 TRP C CZ3 1 
ATOM   6796  C CH2 . TRP C 2 193 ? 157.605 145.062 112.803 1.00 22.66  ? 168 TRP C CH2 1 
ATOM   6797  N N   . ARG C 2 194 ? 161.172 149.531 108.324 1.00 44.23  ? 169 ARG C N   1 
ATOM   6798  C CA  . ARG C 2 194 ? 161.332 150.764 107.556 1.00 40.84  ? 169 ARG C CA  1 
ATOM   6799  C C   . ARG C 2 194 ? 161.161 151.960 108.482 1.00 40.93  ? 169 ARG C C   1 
ATOM   6800  O O   . ARG C 2 194 ? 160.041 152.329 108.841 1.00 40.62  ? 169 ARG C O   1 
ATOM   6801  C CB  . ARG C 2 194 ? 160.320 150.812 106.419 1.00 39.56  ? 169 ARG C CB  1 
ATOM   6802  C CG  . ARG C 2 194 ? 160.425 152.055 105.561 1.00 48.31  ? 169 ARG C CG  1 
ATOM   6803  C CD  . ARG C 2 194 ? 159.400 152.039 104.446 1.00 58.50  ? 169 ARG C CD  1 
ATOM   6804  N NE  . ARG C 2 194 ? 159.390 153.289 103.698 1.00 66.29  ? 169 ARG C NE  1 
ATOM   6805  C CZ  . ARG C 2 194 ? 158.712 154.370 104.055 1.00 68.40  ? 169 ARG C CZ  1 
ATOM   6806  N NH1 . ARG C 2 194 ? 157.975 154.392 105.154 1.00 69.71  ? 169 ARG C NH1 1 
ATOM   6807  N NH2 . ARG C 2 194 ? 158.775 155.458 103.293 1.00 67.17  ? 169 ARG C NH2 1 
ATOM   6808  N N   . GLY C 2 195 ? 162.270 152.576 108.861 1.00 46.54  ? 170 GLY C N   1 
ATOM   6809  C CA  . GLY C 2 195 ? 162.272 153.676 109.794 1.00 48.90  ? 170 GLY C CA  1 
ATOM   6810  C C   . GLY C 2 195 ? 162.933 153.401 111.134 1.00 49.96  ? 170 GLY C C   1 
ATOM   6811  O O   . GLY C 2 195 ? 162.726 154.181 112.073 1.00 46.50  ? 170 GLY C O   1 
ATOM   6812  N N   . GLY C 2 196 ? 163.716 152.331 111.250 1.00 48.70  ? 171 GLY C N   1 
ATOM   6813  C CA  . GLY C 2 196 ? 164.378 152.011 112.502 1.00 43.12  ? 171 GLY C CA  1 
ATOM   6814  C C   . GLY C 2 196 ? 163.383 151.722 113.606 1.00 47.62  ? 171 GLY C C   1 
ATOM   6815  O O   . GLY C 2 196 ? 162.368 151.047 113.405 1.00 47.05  ? 171 GLY C O   1 
ATOM   6816  N N   . ASP C 2 197 ? 163.673 152.246 114.798 1.00 53.97  ? 172 ASP C N   1 
ATOM   6817  C CA  . ASP C 2 197 ? 162.796 152.048 115.944 1.00 55.56  ? 172 ASP C CA  1 
ATOM   6818  C C   . ASP C 2 197 ? 161.498 152.834 115.838 1.00 56.89  ? 172 ASP C C   1 
ATOM   6819  O O   . ASP C 2 197 ? 160.597 152.621 116.656 1.00 56.24  ? 172 ASP C O   1 
ATOM   6820  C CB  . ASP C 2 197 ? 163.526 152.424 117.234 1.00 60.31  ? 172 ASP C CB  1 
ATOM   6821  C CG  . ASP C 2 197 ? 164.698 151.509 117.526 1.00 73.59  ? 172 ASP C CG  1 
ATOM   6822  O OD1 . ASP C 2 197 ? 164.588 150.296 117.249 1.00 67.26  ? 172 ASP C OD1 1 
ATOM   6823  O OD2 . ASP C 2 197 ? 165.728 152.002 118.031 1.00 85.83  ? 172 ASP C OD2 1 
ATOM   6824  N N   . LYS C 2 198 ? 161.381 153.730 114.862 1.00 52.50  ? 173 LYS C N   1 
ATOM   6825  C CA  . LYS C 2 198 ? 160.147 154.459 114.608 1.00 50.37  ? 173 LYS C CA  1 
ATOM   6826  C C   . LYS C 2 198 ? 159.247 153.761 113.599 1.00 46.02  ? 173 LYS C C   1 
ATOM   6827  O O   . LYS C 2 198 ? 158.213 154.323 113.223 1.00 43.06  ? 173 LYS C O   1 
ATOM   6828  C CB  . LYS C 2 198 ? 160.462 155.876 114.122 1.00 55.46  ? 173 LYS C CB  1 
ATOM   6829  C CG  . LYS C 2 198 ? 161.371 156.665 115.050 1.00 62.48  ? 173 LYS C CG  1 
ATOM   6830  C CD  . LYS C 2 198 ? 161.625 158.064 114.509 1.00 70.69  ? 173 LYS C CD  1 
ATOM   6831  C CE  . LYS C 2 198 ? 162.607 158.825 115.383 1.00 76.62  ? 173 LYS C CE  1 
ATOM   6832  N NZ  . LYS C 2 198 ? 162.087 159.020 116.764 1.00 77.94  ? 173 LYS C NZ  1 
ATOM   6833  N N   . ALA C 2 199 ? 159.614 152.559 113.150 1.00 43.66  ? 174 ALA C N   1 
ATOM   6834  C CA  . ALA C 2 199 ? 158.795 151.844 112.179 1.00 36.53  ? 174 ALA C CA  1 
ATOM   6835  C C   . ALA C 2 199 ? 157.429 151.461 112.733 1.00 34.04  ? 174 ALA C C   1 
ATOM   6836  O O   . ALA C 2 199 ? 156.524 151.157 111.954 1.00 36.47  ? 174 ALA C O   1 
ATOM   6837  C CB  . ALA C 2 199 ? 159.528 150.594 111.693 1.00 32.49  ? 174 ALA C CB  1 
ATOM   6838  N N   . VAL C 2 200 ? 157.248 151.470 114.049 1.00 37.46  ? 175 VAL C N   1 
ATOM   6839  C CA  . VAL C 2 200 ? 155.961 151.161 114.658 1.00 31.55  ? 175 VAL C CA  1 
ATOM   6840  C C   . VAL C 2 200 ? 155.501 152.381 115.436 1.00 34.50  ? 175 VAL C C   1 
ATOM   6841  O O   . VAL C 2 200 ? 156.228 152.884 116.300 1.00 40.24  ? 175 VAL C O   1 
ATOM   6842  C CB  . VAL C 2 200 ? 156.039 149.922 115.566 1.00 30.10  ? 175 VAL C CB  1 
ATOM   6843  C CG1 . VAL C 2 200 ? 154.774 149.796 116.393 1.00 33.09  ? 175 VAL C CG1 1 
ATOM   6844  C CG2 . VAL C 2 200 ? 156.230 148.679 114.726 1.00 31.93  ? 175 VAL C CG2 1 
ATOM   6845  N N   . THR C 2 201 ? 154.297 152.854 115.129 1.00 32.93  ? 176 THR C N   1 
ATOM   6846  C CA  . THR C 2 201 ? 153.705 153.992 115.810 1.00 38.99  ? 176 THR C CA  1 
ATOM   6847  C C   . THR C 2 201 ? 152.328 153.601 116.324 1.00 39.09  ? 176 THR C C   1 
ATOM   6848  O O   . THR C 2 201 ? 151.826 152.507 116.056 1.00 40.91  ? 176 THR C O   1 
ATOM   6849  C CB  . THR C 2 201 ? 153.605 155.207 114.875 1.00 42.84  ? 176 THR C CB  1 
ATOM   6850  O OG1 . THR C 2 201 ? 154.608 155.108 113.857 1.00 43.85  ? 176 THR C OG1 1 
ATOM   6851  C CG2 . THR C 2 201 ? 153.820 156.501 115.648 1.00 47.41  ? 176 THR C CG2 1 
ATOM   6852  N N   . GLY C 2 202 ? 151.714 154.512 117.072 1.00 44.23  ? 177 GLY C N   1 
ATOM   6853  C CA  . GLY C 2 202 ? 150.389 154.285 117.604 1.00 49.69  ? 177 GLY C CA  1 
ATOM   6854  C C   . GLY C 2 202 ? 150.332 153.482 118.878 1.00 50.09  ? 177 GLY C C   1 
ATOM   6855  O O   . GLY C 2 202 ? 149.233 153.129 119.318 1.00 53.09  ? 177 GLY C O   1 
ATOM   6856  N N   . VAL C 2 203 ? 151.479 153.170 119.483 1.00 51.15  ? 178 VAL C N   1 
ATOM   6857  C CA  . VAL C 2 203 ? 151.471 152.389 120.713 1.00 52.97  ? 178 VAL C CA  1 
ATOM   6858  C C   . VAL C 2 203 ? 150.802 153.162 121.842 1.00 61.87  ? 178 VAL C C   1 
ATOM   6859  O O   . VAL C 2 203 ? 150.118 152.572 122.687 1.00 61.72  ? 178 VAL C O   1 
ATOM   6860  C CB  . VAL C 2 203 ? 152.906 151.968 121.078 1.00 47.86  ? 178 VAL C CB  1 
ATOM   6861  C CG1 . VAL C 2 203 ? 152.910 151.121 122.337 1.00 47.41  ? 178 VAL C CG1 1 
ATOM   6862  C CG2 . VAL C 2 203 ? 153.540 151.214 119.922 1.00 39.41  ? 178 VAL C CG2 1 
ATOM   6863  N N   . GLU C 2 204 ? 150.970 154.488 121.873 1.00 65.32  ? 179 GLU C N   1 
ATOM   6864  C CA  . GLU C 2 204 ? 150.299 155.301 122.881 1.00 67.80  ? 179 GLU C CA  1 
ATOM   6865  C C   . GLU C 2 204 ? 148.786 155.321 122.701 1.00 71.25  ? 179 GLU C C   1 
ATOM   6866  O O   . GLU C 2 204 ? 148.071 155.729 123.623 1.00 68.56  ? 179 GLU C O   1 
ATOM   6867  C CB  . GLU C 2 204 ? 150.846 156.730 122.866 1.00 68.85  ? 179 GLU C CB  1 
ATOM   6868  C CG  . GLU C 2 204 ? 150.354 157.601 121.714 1.00 77.19  ? 179 GLU C CG  1 
ATOM   6869  C CD  . GLU C 2 204 ? 150.826 157.116 120.358 1.00 75.37  ? 179 GLU C CD  1 
ATOM   6870  O OE1 . GLU C 2 204 ? 151.909 156.497 120.289 1.00 71.73  ? 179 GLU C OE1 1 
ATOM   6871  O OE2 . GLU C 2 204 ? 150.114 157.358 119.360 1.00 75.81  ? 179 GLU C OE2 1 
ATOM   6872  N N   . ARG C 2 205 ? 148.281 154.895 121.541 1.00 70.81  ? 180 ARG C N   1 
ATOM   6873  C CA  . ARG C 2 205 ? 146.842 154.800 121.339 1.00 71.66  ? 180 ARG C CA  1 
ATOM   6874  C C   . ARG C 2 205 ? 146.243 153.602 122.062 1.00 67.91  ? 180 ARG C C   1 
ATOM   6875  O O   . ARG C 2 205 ? 145.034 153.588 122.316 1.00 69.89  ? 180 ARG C O   1 
ATOM   6876  C CB  . ARG C 2 205 ? 146.508 154.735 119.847 1.00 76.27  ? 180 ARG C CB  1 
ATOM   6877  C CG  . ARG C 2 205 ? 146.945 155.964 119.065 1.00 71.75  ? 180 ARG C CG  1 
ATOM   6878  C CD  . ARG C 2 205 ? 146.300 156.005 117.690 1.00 70.36  ? 180 ARG C CD  1 
ATOM   6879  N NE  . ARG C 2 205 ? 146.796 157.115 116.885 1.00 89.66  ? 180 ARG C NE  1 
ATOM   6880  C CZ  . ARG C 2 205 ? 147.748 157.010 115.967 1.00 88.71  ? 180 ARG C CZ  1 
ATOM   6881  N NH1 . ARG C 2 205 ? 148.324 155.851 115.697 1.00 79.76  ? 180 ARG C NH1 1 
ATOM   6882  N NH2 . ARG C 2 205 ? 148.128 158.096 115.300 1.00 84.68  ? 180 ARG C NH2 1 
ATOM   6883  N N   . ILE C 2 206 ? 147.064 152.601 122.383 1.00 64.61  ? 181 ILE C N   1 
ATOM   6884  C CA  . ILE C 2 206 ? 146.575 151.360 122.970 1.00 60.20  ? 181 ILE C CA  1 
ATOM   6885  C C   . ILE C 2 206 ? 146.003 151.654 124.349 1.00 64.45  ? 181 ILE C C   1 
ATOM   6886  O O   . ILE C 2 206 ? 146.671 152.249 125.204 1.00 65.91  ? 181 ILE C O   1 
ATOM   6887  C CB  . ILE C 2 206 ? 147.696 150.314 123.040 1.00 56.90  ? 181 ILE C CB  1 
ATOM   6888  C CG1 . ILE C 2 206 ? 148.218 150.000 121.639 1.00 55.12  ? 181 ILE C CG1 1 
ATOM   6889  C CG2 . ILE C 2 206 ? 147.198 149.049 123.712 1.00 51.96  ? 181 ILE C CG2 1 
ATOM   6890  C CD1 . ILE C 2 206 ? 149.535 149.264 121.634 1.00 50.19  ? 181 ILE C CD1 1 
ATOM   6891  N N   . GLU C 2 207 ? 144.758 151.239 124.570 1.00 60.11  ? 182 GLU C N   1 
ATOM   6892  C CA  . GLU C 2 207 ? 144.066 151.446 125.841 1.00 54.48  ? 182 GLU C CA  1 
ATOM   6893  C C   . GLU C 2 207 ? 143.503 150.107 126.303 1.00 49.20  ? 182 GLU C C   1 
ATOM   6894  O O   . GLU C 2 207 ? 142.353 149.765 126.016 1.00 55.07  ? 182 GLU C O   1 
ATOM   6895  C CB  . GLU C 2 207 ? 142.966 152.492 125.692 1.00 56.63  ? 182 GLU C CB  1 
ATOM   6896  C CG  . GLU C 2 207 ? 143.459 153.859 125.254 1.00 66.04  ? 182 GLU C CG  1 
ATOM   6897  C CD  . GLU C 2 207 ? 142.366 154.906 125.284 1.00 76.84  ? 182 GLU C CD  1 
ATOM   6898  O OE1 . GLU C 2 207 ? 141.588 154.928 126.261 1.00 75.89  ? 182 GLU C OE1 1 
ATOM   6899  O OE2 . GLU C 2 207 ? 142.280 155.703 124.327 1.00 87.07  ? 182 GLU C OE2 1 
ATOM   6900  N N   . LEU C 2 208 ? 144.333 149.350 127.014 1.00 45.18  ? 183 LEU C N   1 
ATOM   6901  C CA  . LEU C 2 208 ? 143.912 148.096 127.618 1.00 46.49  ? 183 LEU C CA  1 
ATOM   6902  C C   . LEU C 2 208 ? 143.431 148.369 129.034 1.00 49.38  ? 183 LEU C C   1 
ATOM   6903  O O   . LEU C 2 208 ? 144.188 148.940 129.830 1.00 48.79  ? 183 LEU C O   1 
ATOM   6904  C CB  . LEU C 2 208 ? 145.060 147.101 127.648 1.00 42.57  ? 183 LEU C CB  1 
ATOM   6905  C CG  . LEU C 2 208 ? 145.439 146.398 126.348 1.00 40.94  ? 183 LEU C CG  1 
ATOM   6906  C CD1 . LEU C 2 208 ? 146.784 145.717 126.490 1.00 36.95  ? 183 LEU C CD1 1 
ATOM   6907  C CD2 . LEU C 2 208 ? 144.375 145.380 126.006 1.00 44.94  ? 183 LEU C CD2 1 
ATOM   6908  N N   . PRO C 2 209 ? 142.194 148.014 129.386 1.00 45.93  ? 184 PRO C N   1 
ATOM   6909  C CA  . PRO C 2 209 ? 141.736 148.278 130.758 1.00 43.45  ? 184 PRO C CA  1 
ATOM   6910  C C   . PRO C 2 209 ? 142.564 147.566 131.809 1.00 42.99  ? 184 PRO C C   1 
ATOM   6911  O O   . PRO C 2 209 ? 142.745 148.101 132.910 1.00 47.64  ? 184 PRO C O   1 
ATOM   6912  C CB  . PRO C 2 209 ? 140.285 147.781 130.742 1.00 44.68  ? 184 PRO C CB  1 
ATOM   6913  C CG  . PRO C 2 209 ? 140.233 146.793 129.628 1.00 37.83  ? 184 PRO C CG  1 
ATOM   6914  C CD  . PRO C 2 209 ? 141.184 147.301 128.589 1.00 43.02  ? 184 PRO C CD  1 
ATOM   6915  N N   . GLN C 2 210 ? 143.074 146.372 131.506 1.00 36.80  ? 185 GLN C N   1 
ATOM   6916  C CA  . GLN C 2 210 ? 143.746 145.556 132.506 1.00 34.72  ? 185 GLN C CA  1 
ATOM   6917  C C   . GLN C 2 210 ? 145.261 145.691 132.477 1.00 38.19  ? 185 GLN C C   1 
ATOM   6918  O O   . GLN C 2 210 ? 145.913 145.425 133.492 1.00 39.35  ? 185 GLN C O   1 
ATOM   6919  C CB  . GLN C 2 210 ? 143.356 144.082 132.332 1.00 33.65  ? 185 GLN C CB  1 
ATOM   6920  C CG  . GLN C 2 210 ? 143.913 143.169 133.407 1.00 40.18  ? 185 GLN C CG  1 
ATOM   6921  C CD  . GLN C 2 210 ? 143.097 141.914 133.597 1.00 46.38  ? 185 GLN C CD  1 
ATOM   6922  O OE1 . GLN C 2 210 ? 143.140 141.294 134.658 1.00 39.92  ? 185 GLN C OE1 1 
ATOM   6923  N NE2 . GLN C 2 210 ? 142.345 141.530 132.571 1.00 55.40  ? 185 GLN C NE2 1 
ATOM   6924  N N   . PHE C 2 211 ? 145.831 146.135 131.364 1.00 38.69  ? 186 PHE C N   1 
ATOM   6925  C CA  . PHE C 2 211 ? 147.271 146.258 131.223 1.00 35.16  ? 186 PHE C CA  1 
ATOM   6926  C C   . PHE C 2 211 ? 147.653 147.697 130.907 1.00 31.94  ? 186 PHE C C   1 
ATOM   6927  O O   . PHE C 2 211 ? 146.805 148.563 130.684 1.00 34.97  ? 186 PHE C O   1 
ATOM   6928  C CB  . PHE C 2 211 ? 147.796 145.336 130.114 1.00 34.15  ? 186 PHE C CB  1 
ATOM   6929  C CG  . PHE C 2 211 ? 147.574 143.877 130.375 1.00 36.73  ? 186 PHE C CG  1 
ATOM   6930  C CD1 . PHE C 2 211 ? 148.441 143.165 131.183 1.00 37.42  ? 186 PHE C CD1 1 
ATOM   6931  C CD2 . PHE C 2 211 ? 146.499 143.217 129.809 1.00 30.11  ? 186 PHE C CD2 1 
ATOM   6932  C CE1 . PHE C 2 211 ? 148.241 141.822 131.421 1.00 34.27  ? 186 PHE C CE1 1 
ATOM   6933  C CE2 . PHE C 2 211 ? 146.293 141.875 130.045 1.00 28.06  ? 186 PHE C CE2 1 
ATOM   6934  C CZ  . PHE C 2 211 ? 147.165 141.176 130.851 1.00 31.82  ? 186 PHE C CZ  1 
ATOM   6935  N N   . SER C 2 212 ? 148.959 147.938 130.902 1.00 30.59  ? 187 SER C N   1 
ATOM   6936  C CA  . SER C 2 212 ? 149.533 149.167 130.380 1.00 36.48  ? 187 SER C CA  1 
ATOM   6937  C C   . SER C 2 212 ? 150.760 148.790 129.571 1.00 32.51  ? 187 SER C C   1 
ATOM   6938  O O   . SER C 2 212 ? 151.572 147.979 130.027 1.00 30.89  ? 187 SER C O   1 
ATOM   6939  C CB  . SER C 2 212 ? 149.905 150.137 131.506 1.00 41.82  ? 187 SER C CB  1 
ATOM   6940  O OG  . SER C 2 212 ? 150.992 149.640 132.267 1.00 45.30  ? 187 SER C OG  1 
ATOM   6941  N N   . ILE C 2 213 ? 150.899 149.364 128.379 1.00 31.29  ? 188 ILE C N   1 
ATOM   6942  C CA  . ILE C 2 213 ? 152.036 149.015 127.533 1.00 31.00  ? 188 ILE C CA  1 
ATOM   6943  C C   . ILE C 2 213 ? 153.273 149.659 128.149 1.00 36.85  ? 188 ILE C C   1 
ATOM   6944  O O   . ILE C 2 213 ? 153.382 150.887 128.205 1.00 41.35  ? 188 ILE C O   1 
ATOM   6945  C CB  . ILE C 2 213 ? 151.832 149.475 126.086 1.00 30.02  ? 188 ILE C CB  1 
ATOM   6946  C CG1 . ILE C 2 213 ? 150.415 149.163 125.601 1.00 29.70  ? 188 ILE C CG1 1 
ATOM   6947  C CG2 . ILE C 2 213 ? 152.850 148.809 125.178 1.00 31.67  ? 188 ILE C CG2 1 
ATOM   6948  C CD1 . ILE C 2 213 ? 150.020 147.717 125.728 1.00 30.50  ? 188 ILE C CD1 1 
ATOM   6949  N N   . VAL C 2 214 ? 154.207 148.835 128.611 1.00 39.30  ? 189 VAL C N   1 
ATOM   6950  C CA  . VAL C 2 214 ? 155.411 149.348 129.252 1.00 43.81  ? 189 VAL C CA  1 
ATOM   6951  C C   . VAL C 2 214 ? 156.490 149.666 128.229 1.00 46.77  ? 189 VAL C C   1 
ATOM   6952  O O   . VAL C 2 214 ? 157.213 150.655 128.367 1.00 57.43  ? 189 VAL C O   1 
ATOM   6953  C CB  . VAL C 2 214 ? 155.907 148.337 130.304 1.00 41.87  ? 189 VAL C CB  1 
ATOM   6954  C CG1 . VAL C 2 214 ? 157.259 148.754 130.853 1.00 42.12  ? 189 VAL C CG1 1 
ATOM   6955  C CG2 . VAL C 2 214 ? 154.894 148.210 131.426 1.00 37.41  ? 189 VAL C CG2 1 
ATOM   6956  N N   . GLU C 2 215 ? 156.592 148.857 127.181 1.00 41.13  ? 190 GLU C N   1 
ATOM   6957  C CA  . GLU C 2 215 ? 157.679 148.983 126.223 1.00 42.82  ? 190 GLU C CA  1 
ATOM   6958  C C   . GLU C 2 215 ? 157.309 148.183 124.985 1.00 41.38  ? 190 GLU C C   1 
ATOM   6959  O O   . GLU C 2 215 ? 156.429 147.319 125.025 1.00 46.95  ? 190 GLU C O   1 
ATOM   6960  C CB  . GLU C 2 215 ? 159.001 148.490 126.827 1.00 49.29  ? 190 GLU C CB  1 
ATOM   6961  C CG  . GLU C 2 215 ? 160.248 148.778 126.011 1.00 59.92  ? 190 GLU C CG  1 
ATOM   6962  C CD  . GLU C 2 215 ? 161.499 148.231 126.667 1.00 73.66  ? 190 GLU C CD  1 
ATOM   6963  O OE1 . GLU C 2 215 ? 161.373 147.346 127.539 1.00 66.10  ? 190 GLU C OE1 1 
ATOM   6964  O OE2 . GLU C 2 215 ? 162.607 148.686 126.312 1.00 81.89  ? 190 GLU C OE2 1 
ATOM   6965  N N   . HIS C 2 216 ? 157.981 148.491 123.881 1.00 35.42  ? 191 HIS C N   1 
ATOM   6966  C CA  . HIS C 2 216 ? 157.884 147.682 122.679 1.00 31.88  ? 191 HIS C CA  1 
ATOM   6967  C C   . HIS C 2 216 ? 159.228 147.714 121.970 1.00 36.56  ? 191 HIS C C   1 
ATOM   6968  O O   . HIS C 2 216 ? 159.993 148.672 122.108 1.00 45.41  ? 191 HIS C O   1 
ATOM   6969  C CB  . HIS C 2 216 ? 156.764 148.175 121.753 1.00 34.21  ? 191 HIS C CB  1 
ATOM   6970  C CG  . HIS C 2 216 ? 157.131 149.378 120.942 1.00 39.47  ? 191 HIS C CG  1 
ATOM   6971  N ND1 . HIS C 2 216 ? 157.093 150.658 121.449 1.00 38.62  ? 191 HIS C ND1 1 
ATOM   6972  C CD2 . HIS C 2 216 ? 157.535 149.495 119.655 1.00 36.67  ? 191 HIS C CD2 1 
ATOM   6973  C CE1 . HIS C 2 216 ? 157.463 151.512 120.512 1.00 35.02  ? 191 HIS C CE1 1 
ATOM   6974  N NE2 . HIS C 2 216 ? 157.737 150.832 119.413 1.00 36.26  ? 191 HIS C NE2 1 
ATOM   6975  N N   . ARG C 2 217 ? 159.509 146.659 121.212 1.00 31.69  ? 192 ARG C N   1 
ATOM   6976  C CA  . ARG C 2 217 ? 160.796 146.518 120.550 1.00 33.43  ? 192 ARG C CA  1 
ATOM   6977  C C   . ARG C 2 217 ? 160.586 146.033 119.126 1.00 30.68  ? 192 ARG C C   1 
ATOM   6978  O O   . ARG C 2 217 ? 159.580 145.396 118.811 1.00 29.70  ? 192 ARG C O   1 
ATOM   6979  C CB  . ARG C 2 217 ? 161.724 145.551 121.294 1.00 34.51  ? 192 ARG C CB  1 
ATOM   6980  C CG  . ARG C 2 217 ? 162.231 146.076 122.623 1.00 48.98  ? 192 ARG C CG  1 
ATOM   6981  C CD  . ARG C 2 217 ? 163.078 145.039 123.335 1.00 56.87  ? 192 ARG C CD  1 
ATOM   6982  N NE  . ARG C 2 217 ? 163.390 145.437 124.702 1.00 60.51  ? 192 ARG C NE  1 
ATOM   6983  C CZ  . ARG C 2 217 ? 163.851 144.614 125.633 1.00 62.61  ? 192 ARG C CZ  1 
ATOM   6984  N NH1 . ARG C 2 217 ? 164.056 143.332 125.383 1.00 61.55  ? 192 ARG C NH1 1 
ATOM   6985  N NH2 . ARG C 2 217 ? 164.107 145.089 126.849 1.00 65.44  ? 192 ARG C NH2 1 
ATOM   6986  N N   . LEU C 2 218 ? 161.557 146.340 118.273 1.00 31.37  ? 193 LEU C N   1 
ATOM   6987  C CA  . LEU C 2 218 ? 161.618 145.813 116.919 1.00 28.18  ? 193 LEU C CA  1 
ATOM   6988  C C   . LEU C 2 218 ? 162.902 145.015 116.776 1.00 30.03  ? 193 LEU C C   1 
ATOM   6989  O O   . LEU C 2 218 ? 163.983 145.506 117.119 1.00 34.04  ? 193 LEU C O   1 
ATOM   6990  C CB  . LEU C 2 218 ? 161.565 146.942 115.890 1.00 27.62  ? 193 LEU C CB  1 
ATOM   6991  C CG  . LEU C 2 218 ? 160.349 147.856 116.025 1.00 26.97  ? 193 LEU C CG  1 
ATOM   6992  C CD1 . LEU C 2 218 ? 160.314 148.884 114.911 1.00 32.53  ? 193 LEU C CD1 1 
ATOM   6993  C CD2 . LEU C 2 218 ? 159.078 147.032 116.047 1.00 27.50  ? 193 LEU C CD2 1 
ATOM   6994  N N   . VAL C 2 219 ? 162.786 143.795 116.263 1.00 29.79  ? 194 VAL C N   1 
ATOM   6995  C CA  . VAL C 2 219 ? 163.925 142.905 116.085 1.00 27.22  ? 194 VAL C CA  1 
ATOM   6996  C C   . VAL C 2 219 ? 163.952 142.427 114.643 1.00 30.50  ? 194 VAL C C   1 
ATOM   6997  O O   . VAL C 2 219 ? 162.920 142.017 114.100 1.00 35.10  ? 194 VAL C O   1 
ATOM   6998  C CB  . VAL C 2 219 ? 163.865 141.703 117.048 1.00 30.06  ? 194 VAL C CB  1 
ATOM   6999  C CG1 . VAL C 2 219 ? 165.085 140.816 116.868 1.00 41.46  ? 194 VAL C CG1 1 
ATOM   7000  C CG2 . VAL C 2 219 ? 163.752 142.178 118.489 1.00 34.33  ? 194 VAL C CG2 1 
ATOM   7001  N N   . SER C 2 220 ? 165.127 142.486 114.025 1.00 29.71  ? 195 SER C N   1 
ATOM   7002  C CA  . SER C 2 220 ? 165.351 141.946 112.693 1.00 36.08  ? 195 SER C CA  1 
ATOM   7003  C C   . SER C 2 220 ? 166.448 140.898 112.782 1.00 44.23  ? 195 SER C C   1 
ATOM   7004  O O   . SER C 2 220 ? 167.537 141.177 113.296 1.00 55.50  ? 195 SER C O   1 
ATOM   7005  C CB  . SER C 2 220 ? 165.740 143.045 111.703 1.00 34.68  ? 195 SER C CB  1 
ATOM   7006  O OG  . SER C 2 220 ? 165.878 142.522 110.393 1.00 33.40  ? 195 SER C OG  1 
ATOM   7007  N N   . ARG C 2 221 ? 166.163 139.699 112.283 1.00 42.92  ? 196 ARG C N   1 
ATOM   7008  C CA  . ARG C 2 221 ? 167.081 138.582 112.427 1.00 49.73  ? 196 ARG C CA  1 
ATOM   7009  C C   . ARG C 2 221 ? 166.846 137.590 111.301 1.00 54.53  ? 196 ARG C C   1 
ATOM   7010  O O   . ARG C 2 221 ? 165.814 137.616 110.625 1.00 58.60  ? 196 ARG C O   1 
ATOM   7011  C CB  . ARG C 2 221 ? 166.917 137.888 113.783 1.00 47.81  ? 196 ARG C CB  1 
ATOM   7012  C CG  . ARG C 2 221 ? 165.473 137.631 114.166 1.00 48.27  ? 196 ARG C CG  1 
ATOM   7013  C CD  . ARG C 2 221 ? 165.373 136.774 115.413 1.00 58.22  ? 196 ARG C CD  1 
ATOM   7014  N NE  . ARG C 2 221 ? 166.010 135.477 115.227 1.00 73.37  ? 196 ARG C NE  1 
ATOM   7015  C CZ  . ARG C 2 221 ? 165.582 134.348 115.776 1.00 85.40  ? 196 ARG C CZ  1 
ATOM   7016  N NH1 . ARG C 2 221 ? 164.492 134.313 116.524 1.00 75.09  ? 196 ARG C NH1 1 
ATOM   7017  N NH2 . ARG C 2 221 ? 166.256 133.223 115.555 1.00 89.09  ? 196 ARG C NH2 1 
ATOM   7018  N N   . ASN C 2 222 ? 167.825 136.714 111.106 1.00 55.18  ? 197 ASN C N   1 
ATOM   7019  C CA  . ASN C 2 222 ? 167.733 135.623 110.148 1.00 59.81  ? 197 ASN C CA  1 
ATOM   7020  C C   . ASN C 2 222 ? 167.621 134.309 110.906 1.00 67.74  ? 197 ASN C C   1 
ATOM   7021  O O   . ASN C 2 222 ? 168.427 134.035 111.801 1.00 74.43  ? 197 ASN C O   1 
ATOM   7022  C CB  . ASN C 2 222 ? 168.952 135.603 109.226 1.00 55.94  ? 197 ASN C CB  1 
ATOM   7023  C CG  . ASN C 2 222 ? 168.984 136.784 108.280 1.00 58.96  ? 197 ASN C CG  1 
ATOM   7024  O OD1 . ASN C 2 222 ? 167.951 137.208 107.763 1.00 63.15  ? 197 ASN C OD1 1 
ATOM   7025  N ND2 . ASN C 2 222 ? 170.174 137.323 108.048 1.00 62.64  ? 197 ASN C ND2 1 
ATOM   7026  N N   . VAL C 2 223 ? 166.623 133.505 110.555 1.00 68.79  ? 198 VAL C N   1 
ATOM   7027  C CA  . VAL C 2 223 ? 166.402 132.208 111.182 1.00 77.51  ? 198 VAL C CA  1 
ATOM   7028  C C   . VAL C 2 223 ? 166.992 131.143 110.269 1.00 87.99  ? 198 VAL C C   1 
ATOM   7029  O O   . VAL C 2 223 ? 166.555 130.984 109.123 1.00 88.43  ? 198 VAL C O   1 
ATOM   7030  C CB  . VAL C 2 223 ? 164.910 131.954 111.442 1.00 75.93  ? 198 VAL C CB  1 
ATOM   7031  C CG1 . VAL C 2 223 ? 164.716 130.603 112.096 1.00 87.22  ? 198 VAL C CG1 1 
ATOM   7032  C CG2 . VAL C 2 223 ? 164.337 133.051 112.315 1.00 63.41  ? 198 VAL C CG2 1 
ATOM   7033  N N   . VAL C 2 224 ? 167.978 130.410 110.777 1.00 96.38  ? 199 VAL C N   1 
ATOM   7034  C CA  . VAL C 2 224 ? 168.706 129.412 110.001 1.00 99.79  ? 199 VAL C CA  1 
ATOM   7035  C C   . VAL C 2 224 ? 168.187 128.026 110.360 1.00 100.68 ? 199 VAL C C   1 
ATOM   7036  O O   . VAL C 2 224 ? 168.310 127.584 111.509 1.00 96.63  ? 199 VAL C O   1 
ATOM   7037  C CB  . VAL C 2 224 ? 170.220 129.509 110.246 1.00 96.30  ? 199 VAL C CB  1 
ATOM   7038  C CG1 . VAL C 2 224 ? 170.978 128.704 109.202 1.00 92.67  ? 199 VAL C CG1 1 
ATOM   7039  C CG2 . VAL C 2 224 ? 170.664 130.962 110.233 1.00 87.21  ? 199 VAL C CG2 1 
ATOM   7040  N N   . PHE C 2 225 ? 167.608 127.341 109.380 1.00 102.80 ? 200 PHE C N   1 
ATOM   7041  C CA  . PHE C 2 225 ? 167.218 125.945 109.500 1.00 106.97 ? 200 PHE C CA  1 
ATOM   7042  C C   . PHE C 2 225 ? 168.115 125.091 108.610 1.00 112.99 ? 200 PHE C C   1 
ATOM   7043  O O   . PHE C 2 225 ? 169.050 125.582 107.972 1.00 110.14 ? 200 PHE C O   1 
ATOM   7044  C CB  . PHE C 2 225 ? 165.746 125.748 109.129 1.00 108.48 ? 200 PHE C CB  1 
ATOM   7045  C CG  . PHE C 2 225 ? 164.780 126.402 110.074 1.00 111.93 ? 200 PHE C CG  1 
ATOM   7046  C CD1 . PHE C 2 225 ? 164.759 126.053 111.413 1.00 113.48 ? 200 PHE C CD1 1 
ATOM   7047  C CD2 . PHE C 2 225 ? 163.879 127.349 109.619 1.00 112.21 ? 200 PHE C CD2 1 
ATOM   7048  C CE1 . PHE C 2 225 ? 163.865 126.644 112.284 1.00 111.92 ? 200 PHE C CE1 1 
ATOM   7049  C CE2 . PHE C 2 225 ? 162.983 127.944 110.485 1.00 111.83 ? 200 PHE C CE2 1 
ATOM   7050  C CZ  . PHE C 2 225 ? 162.976 127.589 111.821 1.00 109.33 ? 200 PHE C CZ  1 
ATOM   7051  N N   . ALA C 2 226 ? 167.822 123.789 108.576 1.00 117.45 ? 201 ALA C N   1 
ATOM   7052  C CA  . ALA C 2 226 ? 168.528 122.898 107.664 1.00 116.47 ? 201 ALA C CA  1 
ATOM   7053  C C   . ALA C 2 226 ? 168.260 123.242 106.205 1.00 115.10 ? 201 ALA C C   1 
ATOM   7054  O O   . ALA C 2 226 ? 169.088 122.930 105.342 1.00 110.04 ? 201 ALA C O   1 
ATOM   7055  C CB  . ALA C 2 226 ? 168.140 121.446 107.940 1.00 111.45 ? 201 ALA C CB  1 
ATOM   7056  N N   . THR C 2 227 ? 167.126 123.877 105.913 1.00 115.65 ? 202 THR C N   1 
ATOM   7057  C CA  . THR C 2 227 ? 166.747 124.215 104.549 1.00 113.34 ? 202 THR C CA  1 
ATOM   7058  C C   . THR C 2 227 ? 167.307 125.554 104.085 1.00 112.18 ? 202 THR C C   1 
ATOM   7059  O O   . THR C 2 227 ? 167.240 125.853 102.888 1.00 105.01 ? 202 THR C O   1 
ATOM   7060  C CB  . THR C 2 227 ? 165.220 124.226 104.412 1.00 109.44 ? 202 THR C CB  1 
ATOM   7061  O OG1 . THR C 2 227 ? 164.673 125.284 105.208 1.00 110.68 ? 202 THR C OG1 1 
ATOM   7062  C CG2 . THR C 2 227 ? 164.635 122.900 104.874 1.00 103.08 ? 202 THR C CG2 1 
ATOM   7063  N N   . GLY C 2 228 ? 167.855 126.357 104.989 1.00 111.58 ? 203 GLY C N   1 
ATOM   7064  C CA  . GLY C 2 228 ? 168.425 127.640 104.650 1.00 105.80 ? 203 GLY C CA  1 
ATOM   7065  C C   . GLY C 2 228 ? 168.114 128.665 105.719 1.00 103.12 ? 203 GLY C C   1 
ATOM   7066  O O   . GLY C 2 228 ? 167.663 128.337 106.815 1.00 103.00 ? 203 GLY C O   1 
ATOM   7067  N N   . ALA C 2 229 ? 168.364 129.929 105.386 1.00 102.36 ? 204 ALA C N   1 
ATOM   7068  C CA  . ALA C 2 229 ? 168.113 131.055 106.275 1.00 95.32  ? 204 ALA C CA  1 
ATOM   7069  C C   . ALA C 2 229 ? 166.878 131.812 105.811 1.00 88.71  ? 204 ALA C C   1 
ATOM   7070  O O   . ALA C 2 229 ? 166.743 132.118 104.622 1.00 84.72  ? 204 ALA C O   1 
ATOM   7071  C CB  . ALA C 2 229 ? 169.321 131.993 106.325 1.00 87.43  ? 204 ALA C CB  1 
ATOM   7072  N N   . TYR C 2 230 ? 165.988 132.122 106.750 1.00 85.91  ? 205 TYR C N   1 
ATOM   7073  C CA  . TYR C 2 230 ? 164.717 132.758 106.456 1.00 76.16  ? 205 TYR C CA  1 
ATOM   7074  C C   . TYR C 2 230 ? 164.612 134.087 107.191 1.00 68.36  ? 205 TYR C C   1 
ATOM   7075  O O   . TYR C 2 230 ? 164.897 134.150 108.395 1.00 66.72  ? 205 TYR C O   1 
ATOM   7076  C CB  . TYR C 2 230 ? 163.536 131.850 106.844 1.00 75.15  ? 205 TYR C CB  1 
ATOM   7077  C CG  . TYR C 2 230 ? 163.501 130.538 106.094 1.00 86.57  ? 205 TYR C CG  1 
ATOM   7078  C CD1 . TYR C 2 230 ? 164.359 129.498 106.426 1.00 94.88  ? 205 TYR C CD1 1 
ATOM   7079  C CD2 . TYR C 2 230 ? 162.608 130.342 105.049 1.00 84.30  ? 205 TYR C CD2 1 
ATOM   7080  C CE1 . TYR C 2 230 ? 164.330 128.302 105.739 1.00 99.26  ? 205 TYR C CE1 1 
ATOM   7081  C CE2 . TYR C 2 230 ? 162.570 129.148 104.357 1.00 89.71  ? 205 TYR C CE2 1 
ATOM   7082  C CZ  . TYR C 2 230 ? 163.432 128.132 104.705 1.00 102.29 ? 205 TYR C CZ  1 
ATOM   7083  O OH  . TYR C 2 230 ? 163.395 126.941 104.016 1.00 107.33 ? 205 TYR C OH  1 
ATOM   7084  N N   . PRO C 2 231 ? 164.225 135.163 106.508 1.00 58.61  ? 206 PRO C N   1 
ATOM   7085  C CA  . PRO C 2 231 ? 164.098 136.461 107.179 1.00 47.51  ? 206 PRO C CA  1 
ATOM   7086  C C   . PRO C 2 231 ? 163.035 136.430 108.265 1.00 37.84  ? 206 PRO C C   1 
ATOM   7087  O O   . PRO C 2 231 ? 162.006 135.763 108.138 1.00 38.97  ? 206 PRO C O   1 
ATOM   7088  C CB  . PRO C 2 231 ? 163.710 137.410 106.040 1.00 52.76  ? 206 PRO C CB  1 
ATOM   7089  C CG  . PRO C 2 231 ? 163.081 136.530 105.016 1.00 57.12  ? 206 PRO C CG  1 
ATOM   7090  C CD  . PRO C 2 231 ? 163.799 135.220 105.100 1.00 63.62  ? 206 PRO C CD  1 
ATOM   7091  N N   . ARG C 2 232 ? 163.294 137.167 109.342 1.00 32.70  ? 207 ARG C N   1 
ATOM   7092  C CA  . ARG C 2 232 ? 162.389 137.225 110.480 1.00 29.21  ? 207 ARG C CA  1 
ATOM   7093  C C   . ARG C 2 232 ? 162.326 138.644 111.017 1.00 31.77  ? 207 ARG C C   1 
ATOM   7094  O O   . ARG C 2 232 ? 163.362 139.286 111.208 1.00 37.82  ? 207 ARG C O   1 
ATOM   7095  C CB  . ARG C 2 232 ? 162.838 136.275 111.595 1.00 33.79  ? 207 ARG C CB  1 
ATOM   7096  C CG  . ARG C 2 232 ? 162.050 136.419 112.886 1.00 30.66  ? 207 ARG C CG  1 
ATOM   7097  C CD  . ARG C 2 232 ? 160.688 135.764 112.805 1.00 36.77  ? 207 ARG C CD  1 
ATOM   7098  N NE  . ARG C 2 232 ? 160.780 134.317 112.950 1.00 44.92  ? 207 ARG C NE  1 
ATOM   7099  C CZ  . ARG C 2 232 ? 160.762 133.682 114.114 1.00 43.42  ? 207 ARG C CZ  1 
ATOM   7100  N NH1 . ARG C 2 232 ? 160.662 134.339 115.258 1.00 46.01  ? 207 ARG C NH1 1 
ATOM   7101  N NH2 . ARG C 2 232 ? 160.852 132.356 114.132 1.00 44.11  ? 207 ARG C NH2 1 
ATOM   7102  N N   . LEU C 2 233 ? 161.110 139.125 111.251 1.00 31.92  ? 208 LEU C N   1 
ATOM   7103  C CA  . LEU C 2 233 ? 160.869 140.363 111.973 1.00 30.09  ? 208 LEU C CA  1 
ATOM   7104  C C   . LEU C 2 233 ? 160.010 140.043 113.184 1.00 29.01  ? 208 LEU C C   1 
ATOM   7105  O O   . LEU C 2 233 ? 159.087 139.228 113.099 1.00 33.08  ? 208 LEU C O   1 
ATOM   7106  C CB  . LEU C 2 233 ? 160.166 141.405 111.100 1.00 27.96  ? 208 LEU C CB  1 
ATOM   7107  C CG  . LEU C 2 233 ? 160.948 141.992 109.927 1.00 29.23  ? 208 LEU C CG  1 
ATOM   7108  C CD1 . LEU C 2 233 ? 160.144 143.091 109.260 1.00 32.72  ? 208 LEU C CD1 1 
ATOM   7109  C CD2 . LEU C 2 233 ? 162.298 142.513 110.378 1.00 30.12  ? 208 LEU C CD2 1 
ATOM   7110  N N   . SER C 2 234 ? 160.305 140.685 114.306 1.00 21.44  ? 209 SER C N   1 
ATOM   7111  C CA  . SER C 2 234 ? 159.556 140.453 115.530 1.00 21.51  ? 209 SER C CA  1 
ATOM   7112  C C   . SER C 2 234 ? 159.140 141.783 116.128 1.00 25.18  ? 209 SER C C   1 
ATOM   7113  O O   . SER C 2 234 ? 159.973 142.677 116.306 1.00 35.00  ? 209 SER C O   1 
ATOM   7114  C CB  . SER C 2 234 ? 160.381 139.657 116.544 1.00 25.26  ? 209 SER C CB  1 
ATOM   7115  O OG  . SER C 2 234 ? 160.837 138.437 115.987 1.00 35.75  ? 209 SER C OG  1 
ATOM   7116  N N   . LEU C 2 235 ? 157.857 141.908 116.434 1.00 24.36  ? 210 LEU C N   1 
ATOM   7117  C CA  . LEU C 2 235 ? 157.334 143.012 117.219 1.00 23.25  ? 210 LEU C CA  1 
ATOM   7118  C C   . LEU C 2 235 ? 156.839 142.437 118.535 1.00 28.37  ? 210 LEU C C   1 
ATOM   7119  O O   . LEU C 2 235 ? 156.036 141.500 118.540 1.00 36.80  ? 210 LEU C O   1 
ATOM   7120  C CB  . LEU C 2 235 ? 156.207 143.731 116.474 1.00 24.90  ? 210 LEU C CB  1 
ATOM   7121  C CG  . LEU C 2 235 ? 155.272 144.627 117.283 1.00 30.35  ? 210 LEU C CG  1 
ATOM   7122  C CD1 . LEU C 2 235 ? 156.044 145.770 117.918 1.00 31.39  ? 210 LEU C CD1 1 
ATOM   7123  C CD2 . LEU C 2 235 ? 154.164 145.157 116.390 1.00 34.09  ? 210 LEU C CD2 1 
ATOM   7124  N N   . SER C 2 236 ? 157.313 142.992 119.643 1.00 26.66  ? 211 SER C N   1 
ATOM   7125  C CA  . SER C 2 236 ? 156.990 142.465 120.958 1.00 25.16  ? 211 SER C CA  1 
ATOM   7126  C C   . SER C 2 236 ? 156.568 143.597 121.875 1.00 28.32  ? 211 SER C C   1 
ATOM   7127  O O   . SER C 2 236 ? 157.142 144.688 121.835 1.00 39.13  ? 211 SER C O   1 
ATOM   7128  C CB  . SER C 2 236 ? 158.182 141.721 121.565 1.00 31.24  ? 211 SER C CB  1 
ATOM   7129  O OG  . SER C 2 236 ? 159.368 142.486 121.457 1.00 46.22  ? 211 SER C OG  1 
ATOM   7130  N N   . PHE C 2 237 ? 155.571 143.326 122.707 1.00 26.50  ? 212 PHE C N   1 
ATOM   7131  C CA  . PHE C 2 237 ? 155.126 144.257 123.727 1.00 28.46  ? 212 PHE C CA  1 
ATOM   7132  C C   . PHE C 2 237 ? 155.321 143.623 125.093 1.00 30.62  ? 212 PHE C C   1 
ATOM   7133  O O   . PHE C 2 237 ? 155.198 142.406 125.250 1.00 39.94  ? 212 PHE C O   1 
ATOM   7134  C CB  . PHE C 2 237 ? 153.647 144.616 123.555 1.00 28.23  ? 212 PHE C CB  1 
ATOM   7135  C CG  . PHE C 2 237 ? 153.253 144.894 122.139 1.00 32.80  ? 212 PHE C CG  1 
ATOM   7136  C CD1 . PHE C 2 237 ? 153.535 146.111 121.550 1.00 31.54  ? 212 PHE C CD1 1 
ATOM   7137  C CD2 . PHE C 2 237 ? 152.592 143.931 121.397 1.00 34.09  ? 212 PHE C CD2 1 
ATOM   7138  C CE1 . PHE C 2 237 ? 153.170 146.359 120.246 1.00 32.70  ? 212 PHE C CE1 1 
ATOM   7139  C CE2 . PHE C 2 237 ? 152.224 144.174 120.094 1.00 30.87  ? 212 PHE C CE2 1 
ATOM   7140  C CZ  . PHE C 2 237 ? 152.511 145.389 119.518 1.00 33.91  ? 212 PHE C CZ  1 
ATOM   7141  N N   . ARG C 2 238 ? 155.624 144.451 126.082 1.00 27.81  ? 213 ARG C N   1 
ATOM   7142  C CA  . ARG C 2 238 ? 155.651 144.007 127.465 1.00 28.31  ? 213 ARG C CA  1 
ATOM   7143  C C   . ARG C 2 238 ? 154.456 144.632 128.165 1.00 26.55  ? 213 ARG C C   1 
ATOM   7144  O O   . ARG C 2 238 ? 154.258 145.849 128.097 1.00 29.36  ? 213 ARG C O   1 
ATOM   7145  C CB  . ARG C 2 238 ? 156.963 144.390 128.151 1.00 31.93  ? 213 ARG C CB  1 
ATOM   7146  C CG  . ARG C 2 238 ? 157.203 143.645 129.451 1.00 37.47  ? 213 ARG C CG  1 
ATOM   7147  C CD  . ARG C 2 238 ? 158.675 143.621 129.827 1.00 41.82  ? 213 ARG C CD  1 
ATOM   7148  N NE  . ARG C 2 238 ? 159.055 144.755 130.660 1.00 53.98  ? 213 ARG C NE  1 
ATOM   7149  C CZ  . ARG C 2 238 ? 159.698 145.827 130.218 1.00 66.37  ? 213 ARG C CZ  1 
ATOM   7150  N NH1 . ARG C 2 238 ? 160.059 145.942 128.951 1.00 63.93  ? 213 ARG C NH1 1 
ATOM   7151  N NH2 . ARG C 2 238 ? 159.993 146.804 131.071 1.00 70.18  ? 213 ARG C NH2 1 
ATOM   7152  N N   . LEU C 2 239 ? 153.666 143.801 128.831 1.00 26.89  ? 214 LEU C N   1 
ATOM   7153  C CA  . LEU C 2 239 ? 152.431 144.227 129.470 1.00 28.09  ? 214 LEU C CA  1 
ATOM   7154  C C   . LEU C 2 239 ? 152.563 144.084 130.977 1.00 33.29  ? 214 LEU C C   1 
ATOM   7155  O O   . LEU C 2 239 ? 153.026 143.050 131.467 1.00 33.81  ? 214 LEU C O   1 
ATOM   7156  C CB  . LEU C 2 239 ? 151.247 143.404 128.957 1.00 28.11  ? 214 LEU C CB  1 
ATOM   7157  C CG  . LEU C 2 239 ? 151.189 143.205 127.440 1.00 24.16  ? 214 LEU C CG  1 
ATOM   7158  C CD1 . LEU C 2 239 ? 149.981 142.375 127.035 1.00 26.37  ? 214 LEU C CD1 1 
ATOM   7159  C CD2 . LEU C 2 239 ? 151.185 144.531 126.722 1.00 25.89  ? 214 LEU C CD2 1 
ATOM   7160  N N   . LYS C 2 240 ? 152.152 145.114 131.706 1.00 34.65  ? 215 LYS C N   1 
ATOM   7161  C CA  . LYS C 2 240 ? 152.096 145.071 133.159 1.00 33.84  ? 215 LYS C CA  1 
ATOM   7162  C C   . LYS C 2 240 ? 150.632 145.123 133.567 1.00 33.33  ? 215 LYS C C   1 
ATOM   7163  O O   . LYS C 2 240 ? 149.916 146.062 133.206 1.00 36.60  ? 215 LYS C O   1 
ATOM   7164  C CB  . LYS C 2 240 ? 152.876 146.240 133.761 1.00 39.24  ? 215 LYS C CB  1 
ATOM   7165  C CG  . LYS C 2 240 ? 152.957 146.253 135.273 1.00 44.18  ? 215 LYS C CG  1 
ATOM   7166  C CD  . LYS C 2 240 ? 153.765 147.452 135.743 1.00 54.66  ? 215 LYS C CD  1 
ATOM   7167  C CE  . LYS C 2 240 ? 153.877 147.497 137.256 1.00 76.93  ? 215 LYS C CE  1 
ATOM   7168  N NZ  . LYS C 2 240 ? 154.645 148.689 137.711 1.00 76.06  ? 215 LYS C NZ  1 
ATOM   7169  N N   . ARG C 2 241 ? 150.194 144.120 134.320 1.00 31.29  ? 216 ARG C N   1 
ATOM   7170  C CA  . ARG C 2 241 ? 148.793 144.029 134.701 1.00 32.57  ? 216 ARG C CA  1 
ATOM   7171  C C   . ARG C 2 241 ? 148.472 145.044 135.788 1.00 36.65  ? 216 ARG C C   1 
ATOM   7172  O O   . ARG C 2 241 ? 149.254 145.246 136.720 1.00 37.82  ? 216 ARG C O   1 
ATOM   7173  C CB  . ARG C 2 241 ? 148.467 142.612 135.165 1.00 29.07  ? 216 ARG C CB  1 
ATOM   7174  C CG  . ARG C 2 241 ? 146.985 142.323 135.289 1.00 27.37  ? 216 ARG C CG  1 
ATOM   7175  C CD  . ARG C 2 241 ? 146.751 140.891 135.721 1.00 23.39  ? 216 ARG C CD  1 
ATOM   7176  N NE  . ARG C 2 241 ? 147.313 139.953 134.757 1.00 24.19  ? 216 ARG C NE  1 
ATOM   7177  C CZ  . ARG C 2 241 ? 146.646 139.430 133.738 1.00 29.98  ? 216 ARG C CZ  1 
ATOM   7178  N NH1 . ARG C 2 241 ? 145.380 139.735 133.511 1.00 35.13  ? 216 ARG C NH1 1 
ATOM   7179  N NH2 . ARG C 2 241 ? 147.266 138.580 132.924 1.00 28.18  ? 216 ARG C NH2 1 
ATOM   7180  N N   . ASN C 2 242 ? 147.313 145.689 135.669 1.00 35.10  ? 217 ASN C N   1 
ATOM   7181  C CA  . ASN C 2 242 ? 146.884 146.626 136.697 1.00 34.12  ? 217 ASN C CA  1 
ATOM   7182  C C   . ASN C 2 242 ? 146.396 145.857 137.915 1.00 35.59  ? 217 ASN C C   1 
ATOM   7183  O O   . ASN C 2 242 ? 145.554 144.961 137.804 1.00 39.41  ? 217 ASN C O   1 
ATOM   7184  C CB  . ASN C 2 242 ? 145.785 147.547 136.170 1.00 34.94  ? 217 ASN C CB  1 
ATOM   7185  C CG  . ASN C 2 242 ? 146.233 148.359 134.974 1.00 39.30  ? 217 ASN C CG  1 
ATOM   7186  O OD1 . ASN C 2 242 ? 147.389 148.774 134.890 1.00 40.11  ? 217 ASN C OD1 1 
ATOM   7187  N ND2 . ASN C 2 242 ? 145.317 148.599 134.043 1.00 39.53  ? 217 ASN C ND2 1 
ATOM   7188  N N   . ILE C 2 243 ? 146.929 146.218 139.079 1.00 33.86  ? 218 ILE C N   1 
ATOM   7189  C CA  . ILE C 2 243 ? 146.683 145.471 140.304 1.00 31.38  ? 218 ILE C CA  1 
ATOM   7190  C C   . ILE C 2 243 ? 145.568 146.084 141.148 1.00 35.42  ? 218 ILE C C   1 
ATOM   7191  O O   . ILE C 2 243 ? 145.037 145.401 142.038 1.00 33.51  ? 218 ILE C O   1 
ATOM   7192  C CB  . ILE C 2 243 ? 147.991 145.359 141.119 1.00 26.23  ? 218 ILE C CB  1 
ATOM   7193  C CG1 . ILE C 2 243 ? 147.849 144.381 142.285 1.00 24.75  ? 218 ILE C CG1 1 
ATOM   7194  C CG2 . ILE C 2 243 ? 148.431 146.728 141.613 1.00 26.09  ? 218 ILE C CG2 1 
ATOM   7195  C CD1 . ILE C 2 243 ? 147.533 142.973 141.854 1.00 24.18  ? 218 ILE C CD1 1 
ATOM   7196  N N   . GLY C 2 244 ? 145.174 147.331 140.875 1.00 35.69  ? 219 GLY C N   1 
ATOM   7197  C CA  . GLY C 2 244 ? 144.235 148.013 141.753 1.00 29.76  ? 219 GLY C CA  1 
ATOM   7198  C C   . GLY C 2 244 ? 142.921 147.278 141.930 1.00 28.77  ? 219 GLY C C   1 
ATOM   7199  O O   . GLY C 2 244 ? 142.365 147.248 143.030 1.00 32.39  ? 219 GLY C O   1 
ATOM   7200  N N   . TYR C 2 245 ? 142.388 146.699 140.851 1.00 28.72  ? 220 TYR C N   1 
ATOM   7201  C CA  . TYR C 2 245 ? 141.120 145.987 140.975 1.00 32.80  ? 220 TYR C CA  1 
ATOM   7202  C C   . TYR C 2 245 ? 141.240 144.820 141.936 1.00 31.85  ? 220 TYR C C   1 
ATOM   7203  O O   . TYR C 2 245 ? 140.357 144.601 142.771 1.00 31.59  ? 220 TYR C O   1 
ATOM   7204  C CB  . TYR C 2 245 ? 140.645 145.484 139.620 1.00 27.59  ? 220 TYR C CB  1 
ATOM   7205  C CG  . TYR C 2 245 ? 139.402 144.625 139.664 1.00 26.86  ? 220 TYR C CG  1 
ATOM   7206  C CD1 . TYR C 2 245 ? 138.139 145.200 139.699 1.00 30.91  ? 220 TYR C CD1 1 
ATOM   7207  C CD2 . TYR C 2 245 ? 139.491 143.239 139.644 1.00 25.31  ? 220 TYR C CD2 1 
ATOM   7208  C CE1 . TYR C 2 245 ? 137.000 144.419 139.730 1.00 32.21  ? 220 TYR C CE1 1 
ATOM   7209  C CE2 . TYR C 2 245 ? 138.359 142.451 139.675 1.00 26.94  ? 220 TYR C CE2 1 
ATOM   7210  C CZ  . TYR C 2 245 ? 137.116 143.045 139.715 1.00 30.64  ? 220 TYR C CZ  1 
ATOM   7211  O OH  . TYR C 2 245 ? 135.986 142.262 139.746 1.00 26.61  ? 220 TYR C OH  1 
ATOM   7212  N N   . PHE C 2 246 ? 142.345 144.077 141.859 1.00 28.86  ? 221 PHE C N   1 
ATOM   7213  C CA  . PHE C 2 246 ? 142.477 142.925 142.732 1.00 24.85  ? 221 PHE C CA  1 
ATOM   7214  C C   . PHE C 2 246 ? 142.752 143.345 144.162 1.00 28.68  ? 221 PHE C C   1 
ATOM   7215  O O   . PHE C 2 246 ? 142.476 142.573 145.085 1.00 33.21  ? 221 PHE C O   1 
ATOM   7216  C CB  . PHE C 2 246 ? 143.589 142.008 142.226 1.00 24.13  ? 221 PHE C CB  1 
ATOM   7217  C CG  . PHE C 2 246 ? 143.360 141.491 140.837 1.00 27.27  ? 221 PHE C CG  1 
ATOM   7218  C CD1 . PHE C 2 246 ? 142.623 140.340 140.625 1.00 28.33  ? 221 PHE C CD1 1 
ATOM   7219  C CD2 . PHE C 2 246 ? 143.880 142.158 139.742 1.00 28.93  ? 221 PHE C CD2 1 
ATOM   7220  C CE1 . PHE C 2 246 ? 142.411 139.865 139.345 1.00 29.45  ? 221 PHE C CE1 1 
ATOM   7221  C CE2 . PHE C 2 246 ? 143.671 141.687 138.462 1.00 26.53  ? 221 PHE C CE2 1 
ATOM   7222  C CZ  . PHE C 2 246 ? 142.936 140.539 138.264 1.00 28.22  ? 221 PHE C CZ  1 
ATOM   7223  N N   . ILE C 2 247 ? 143.273 144.555 144.369 1.00 28.42  ? 222 ILE C N   1 
ATOM   7224  C CA  . ILE C 2 247 ? 143.427 145.048 145.730 1.00 27.45  ? 222 ILE C CA  1 
ATOM   7225  C C   . ILE C 2 247 ? 142.060 145.286 146.351 1.00 27.05  ? 222 ILE C C   1 
ATOM   7226  O O   . ILE C 2 247 ? 141.771 144.817 147.455 1.00 28.51  ? 222 ILE C O   1 
ATOM   7227  C CB  . ILE C 2 247 ? 144.285 146.325 145.749 1.00 20.61  ? 222 ILE C CB  1 
ATOM   7228  C CG1 . ILE C 2 247 ? 145.634 146.080 145.074 1.00 20.93  ? 222 ILE C CG1 1 
ATOM   7229  C CG2 . ILE C 2 247 ? 144.482 146.810 147.174 1.00 20.44  ? 222 ILE C CG2 1 
ATOM   7230  C CD1 . ILE C 2 247 ? 146.390 144.902 145.635 1.00 19.98  ? 222 ILE C CD1 1 
ATOM   7231  N N   . LEU C 2 248 ? 141.182 145.987 145.628 1.00 26.34  ? 223 LEU C N   1 
ATOM   7232  C CA  . LEU C 2 248 ? 139.851 146.263 146.156 1.00 27.80  ? 223 LEU C CA  1 
ATOM   7233  C C   . LEU C 2 248 ? 138.976 145.017 146.151 1.00 27.21  ? 223 LEU C C   1 
ATOM   7234  O O   . LEU C 2 248 ? 138.199 144.793 147.085 1.00 30.74  ? 223 LEU C O   1 
ATOM   7235  C CB  . LEU C 2 248 ? 139.200 147.379 145.340 1.00 30.00  ? 223 LEU C CB  1 
ATOM   7236  C CG  . LEU C 2 248 ? 138.144 148.245 146.022 1.00 28.59  ? 223 LEU C CG  1 
ATOM   7237  C CD1 . LEU C 2 248 ? 138.745 148.963 147.215 1.00 31.20  ? 223 LEU C CD1 1 
ATOM   7238  C CD2 . LEU C 2 248 ? 137.571 149.241 145.030 1.00 29.56  ? 223 LEU C CD2 1 
ATOM   7239  N N   . GLN C 2 249 ? 139.088 144.193 145.111 1.00 24.90  ? 224 GLN C N   1 
ATOM   7240  C CA  . GLN C 2 249 ? 138.129 143.119 144.880 1.00 29.09  ? 224 GLN C CA  1 
ATOM   7241  C C   . GLN C 2 249 ? 138.527 141.817 145.563 1.00 29.18  ? 224 GLN C C   1 
ATOM   7242  O O   . GLN C 2 249 ? 137.661 141.085 146.053 1.00 30.48  ? 224 GLN C O   1 
ATOM   7243  C CB  . GLN C 2 249 ? 137.927 142.891 143.381 1.00 29.99  ? 224 GLN C CB  1 
ATOM   7244  C CG  . GLN C 2 249 ? 136.514 142.473 143.010 1.00 30.94  ? 224 GLN C CG  1 
ATOM   7245  C CD  . GLN C 2 249 ? 135.470 143.538 143.312 1.00 36.08  ? 224 GLN C CD  1 
ATOM   7246  O OE1 . GLN C 2 249 ? 135.797 144.681 143.632 1.00 36.73  ? 224 GLN C OE1 1 
ATOM   7247  N NE2 . GLN C 2 249 ? 134.202 143.160 143.214 1.00 40.77  ? 224 GLN C NE2 1 
ATOM   7248  N N   . THR C 2 250 ? 139.823 141.514 145.600 1.00 28.24  ? 225 THR C N   1 
ATOM   7249  C CA  . THR C 2 250 ? 140.316 140.232 146.084 1.00 23.45  ? 225 THR C CA  1 
ATOM   7250  C C   . THR C 2 250 ? 141.130 140.385 147.362 1.00 24.27  ? 225 THR C C   1 
ATOM   7251  O O   . THR C 2 250 ? 140.811 139.753 148.371 1.00 26.95  ? 225 THR C O   1 
ATOM   7252  C CB  . THR C 2 250 ? 141.165 139.550 145.005 1.00 30.82  ? 225 THR C CB  1 
ATOM   7253  O OG1 . THR C 2 250 ? 142.355 140.314 144.788 1.00 37.69  ? 225 THR C OG1 1 
ATOM   7254  C CG2 . THR C 2 250 ? 140.401 139.481 143.702 1.00 33.20  ? 225 THR C CG2 1 
ATOM   7255  N N   . TYR C 2 251 ? 142.187 141.199 147.346 1.00 22.48  ? 226 TYR C N   1 
ATOM   7256  C CA  . TYR C 2 251 ? 143.107 141.200 148.476 1.00 19.60  ? 226 TYR C CA  1 
ATOM   7257  C C   . TYR C 2 251 ? 142.479 141.868 149.693 1.00 22.22  ? 226 TYR C C   1 
ATOM   7258  O O   . TYR C 2 251 ? 142.564 141.341 150.807 1.00 23.80  ? 226 TYR C O   1 
ATOM   7259  C CB  . TYR C 2 251 ? 144.423 141.872 148.089 1.00 17.60  ? 226 TYR C CB  1 
ATOM   7260  C CG  . TYR C 2 251 ? 145.236 141.054 147.115 1.00 20.24  ? 226 TYR C CG  1 
ATOM   7261  C CD1 . TYR C 2 251 ? 146.092 140.061 147.563 1.00 21.36  ? 226 TYR C CD1 1 
ATOM   7262  C CD2 . TYR C 2 251 ? 145.153 141.275 145.749 1.00 21.35  ? 226 TYR C CD2 1 
ATOM   7263  C CE1 . TYR C 2 251 ? 146.835 139.307 146.682 1.00 18.84  ? 226 TYR C CE1 1 
ATOM   7264  C CE2 . TYR C 2 251 ? 145.895 140.525 144.858 1.00 20.44  ? 226 TYR C CE2 1 
ATOM   7265  C CZ  . TYR C 2 251 ? 146.734 139.544 145.333 1.00 18.03  ? 226 TYR C CZ  1 
ATOM   7266  O OH  . TYR C 2 251 ? 147.478 138.794 144.455 1.00 20.50  ? 226 TYR C OH  1 
ATOM   7267  N N   . MET C 2 252 ? 141.840 143.026 149.508 1.00 22.67  ? 227 MET C N   1 
ATOM   7268  C CA  . MET C 2 252 ? 141.287 143.728 150.666 1.00 21.62  ? 227 MET C CA  1 
ATOM   7269  C C   . MET C 2 252 ? 140.173 142.932 151.331 1.00 20.90  ? 227 MET C C   1 
ATOM   7270  O O   . MET C 2 252 ? 140.176 142.834 152.570 1.00 23.34  ? 227 MET C O   1 
ATOM   7271  C CB  . MET C 2 252 ? 140.819 145.135 150.281 1.00 20.41  ? 227 MET C CB  1 
ATOM   7272  C CG  . MET C 2 252 ? 141.912 146.188 150.359 1.00 28.90  ? 227 MET C CG  1 
ATOM   7273  S SD  . MET C 2 252 ? 142.647 146.292 152.000 1.00 51.53  ? 227 MET C SD  1 
ATOM   7274  C CE  . MET C 2 252 ? 143.902 147.542 151.733 1.00 33.41  ? 227 MET C CE  1 
ATOM   7275  N N   . PRO C 2 253 ? 139.190 142.373 150.609 1.00 19.44  ? 228 PRO C N   1 
ATOM   7276  C CA  . PRO C 2 253 ? 138.194 141.548 151.307 1.00 16.76  ? 228 PRO C CA  1 
ATOM   7277  C C   . PRO C 2 253 ? 138.827 140.379 152.034 1.00 17.34  ? 228 PRO C C   1 
ATOM   7278  O O   . PRO C 2 253 ? 138.412 140.052 153.151 1.00 19.47  ? 228 PRO C O   1 
ATOM   7279  C CB  . PRO C 2 253 ? 137.261 141.087 150.180 1.00 16.25  ? 228 PRO C CB  1 
ATOM   7280  C CG  . PRO C 2 253 ? 137.444 142.075 149.104 1.00 19.62  ? 228 PRO C CG  1 
ATOM   7281  C CD  . PRO C 2 253 ? 138.871 142.504 149.177 1.00 22.33  ? 228 PRO C CD  1 
ATOM   7282  N N   . SER C 2 254 ? 139.837 139.743 151.434 1.00 17.30  ? 229 SER C N   1 
ATOM   7283  C CA  . SER C 2 254 ? 140.480 138.616 152.098 1.00 17.33  ? 229 SER C CA  1 
ATOM   7284  C C   . SER C 2 254 ? 141.232 139.077 153.339 1.00 16.25  ? 229 SER C C   1 
ATOM   7285  O O   . SER C 2 254 ? 141.270 138.365 154.349 1.00 17.71  ? 229 SER C O   1 
ATOM   7286  C CB  . SER C 2 254 ? 141.420 137.903 151.130 1.00 15.48  ? 229 SER C CB  1 
ATOM   7287  O OG  . SER C 2 254 ? 140.746 137.557 149.933 1.00 16.60  ? 229 SER C OG  1 
ATOM   7288  N N   . ILE C 2 255 ? 141.849 140.259 153.277 1.00 14.32  ? 230 ILE C N   1 
ATOM   7289  C CA  . ILE C 2 255 ? 142.545 140.793 154.443 1.00 14.59  ? 230 ILE C CA  1 
ATOM   7290  C C   . ILE C 2 255 ? 141.547 141.150 155.534 1.00 14.89  ? 230 ILE C C   1 
ATOM   7291  O O   . ILE C 2 255 ? 141.774 140.880 156.719 1.00 18.86  ? 230 ILE C O   1 
ATOM   7292  C CB  . ILE C 2 255 ? 143.419 141.999 154.055 1.00 15.14  ? 230 ILE C CB  1 
ATOM   7293  C CG1 . ILE C 2 255 ? 144.569 141.559 153.152 1.00 15.32  ? 230 ILE C CG1 1 
ATOM   7294  C CG2 . ILE C 2 255 ? 143.956 142.693 155.292 1.00 11.24  ? 230 ILE C CG2 1 
ATOM   7295  C CD1 . ILE C 2 255 ? 145.239 142.699 152.429 1.00 16.09  ? 230 ILE C CD1 1 
ATOM   7296  N N   . LEU C 2 256 ? 140.416 141.747 155.151 1.00 13.18  ? 231 LEU C N   1 
ATOM   7297  C CA  . LEU C 2 256 ? 139.430 142.164 156.139 1.00 13.73  ? 231 LEU C CA  1 
ATOM   7298  C C   . LEU C 2 256 ? 138.724 140.969 156.763 1.00 14.86  ? 231 LEU C C   1 
ATOM   7299  O O   . LEU C 2 256 ? 138.388 141.003 157.951 1.00 18.10  ? 231 LEU C O   1 
ATOM   7300  C CB  . LEU C 2 256 ? 138.422 143.120 155.503 1.00 12.53  ? 231 LEU C CB  1 
ATOM   7301  C CG  . LEU C 2 256 ? 138.986 144.497 155.139 1.00 14.20  ? 231 LEU C CG  1 
ATOM   7302  C CD1 . LEU C 2 256 ? 137.882 145.458 154.738 1.00 13.54  ? 231 LEU C CD1 1 
ATOM   7303  C CD2 . LEU C 2 256 ? 139.806 145.068 156.284 1.00 11.68  ? 231 LEU C CD2 1 
ATOM   7304  N N   . ILE C 2 257 ? 138.487 139.909 155.988 1.00 15.83  ? 232 ILE C N   1 
ATOM   7305  C CA  . ILE C 2 257 ? 137.897 138.708 156.567 1.00 12.28  ? 232 ILE C CA  1 
ATOM   7306  C C   . ILE C 2 257 ? 138.894 138.040 157.501 1.00 14.31  ? 232 ILE C C   1 
ATOM   7307  O O   . ILE C 2 257 ? 138.527 137.551 158.577 1.00 19.01  ? 232 ILE C O   1 
ATOM   7308  C CB  . ILE C 2 257 ? 137.412 137.747 155.467 1.00 9.27   ? 232 ILE C CB  1 
ATOM   7309  C CG1 . ILE C 2 257 ? 136.312 138.406 154.637 1.00 9.97   ? 232 ILE C CG1 1 
ATOM   7310  C CG2 . ILE C 2 257 ? 136.890 136.463 156.079 1.00 10.03  ? 232 ILE C CG2 1 
ATOM   7311  C CD1 . ILE C 2 257 ? 135.074 138.740 155.425 1.00 13.79  ? 232 ILE C CD1 1 
ATOM   7312  N N   . THR C 2 258 ? 140.171 138.006 157.110 1.00 13.77  ? 233 THR C N   1 
ATOM   7313  C CA  . THR C 2 258 ? 141.181 137.411 157.976 1.00 13.19  ? 233 THR C CA  1 
ATOM   7314  C C   . THR C 2 258 ? 141.320 138.206 159.267 1.00 18.61  ? 233 THR C C   1 
ATOM   7315  O O   . THR C 2 258 ? 141.467 137.625 160.349 1.00 21.62  ? 233 THR C O   1 
ATOM   7316  C CB  . THR C 2 258 ? 142.520 137.328 157.246 1.00 11.60  ? 233 THR C CB  1 
ATOM   7317  O OG1 . THR C 2 258 ? 142.339 136.669 155.988 1.00 10.93  ? 233 THR C OG1 1 
ATOM   7318  C CG2 . THR C 2 258 ? 143.527 136.550 158.071 1.00 12.99  ? 233 THR C CG2 1 
ATOM   7319  N N   . ILE C 2 259 ? 141.282 139.539 159.175 1.00 16.88  ? 234 ILE C N   1 
ATOM   7320  C CA  . ILE C 2 259 ? 141.304 140.360 160.383 1.00 17.30  ? 234 ILE C CA  1 
ATOM   7321  C C   . ILE C 2 259 ? 140.059 140.091 161.216 1.00 18.56  ? 234 ILE C C   1 
ATOM   7322  O O   . ILE C 2 259 ? 140.122 140.006 162.449 1.00 20.49  ? 234 ILE C O   1 
ATOM   7323  C CB  . ILE C 2 259 ? 141.432 141.852 160.024 1.00 13.26  ? 234 ILE C CB  1 
ATOM   7324  C CG1 . ILE C 2 259 ? 142.799 142.143 159.407 1.00 14.22  ? 234 ILE C CG1 1 
ATOM   7325  C CG2 . ILE C 2 259 ? 141.230 142.717 161.255 1.00 12.80  ? 234 ILE C CG2 1 
ATOM   7326  C CD1 . ILE C 2 259 ? 142.884 143.496 158.741 1.00 17.92  ? 234 ILE C CD1 1 
ATOM   7327  N N   . LEU C 2 260 ? 138.906 139.960 160.555 1.00 18.24  ? 235 LEU C N   1 
ATOM   7328  C CA  . LEU C 2 260 ? 137.659 139.726 161.275 1.00 16.39  ? 235 LEU C CA  1 
ATOM   7329  C C   . LEU C 2 260 ? 137.712 138.430 162.068 1.00 16.79  ? 235 LEU C C   1 
ATOM   7330  O O   . LEU C 2 260 ? 137.122 138.339 163.150 1.00 19.43  ? 235 LEU C O   1 
ATOM   7331  C CB  . LEU C 2 260 ? 136.487 139.698 160.293 1.00 15.60  ? 235 LEU C CB  1 
ATOM   7332  C CG  . LEU C 2 260 ? 135.248 140.513 160.657 1.00 13.15  ? 235 LEU C CG  1 
ATOM   7333  C CD1 . LEU C 2 260 ? 135.639 141.843 161.270 1.00 11.93  ? 235 LEU C CD1 1 
ATOM   7334  C CD2 . LEU C 2 260 ? 134.380 140.721 159.432 1.00 10.96  ? 235 LEU C CD2 1 
ATOM   7335  N N   . SER C 2 261 ? 138.415 137.421 161.550 1.00 15.48  ? 236 SER C N   1 
ATOM   7336  C CA  . SER C 2 261 ? 138.554 136.161 162.264 1.00 15.55  ? 236 SER C CA  1 
ATOM   7337  C C   . SER C 2 261 ? 139.339 136.321 163.557 1.00 22.21  ? 236 SER C C   1 
ATOM   7338  O O   . SER C 2 261 ? 139.213 135.477 164.450 1.00 24.04  ? 236 SER C O   1 
ATOM   7339  C CB  . SER C 2 261 ? 139.220 135.119 161.367 1.00 15.71  ? 236 SER C CB  1 
ATOM   7340  O OG  . SER C 2 261 ? 140.548 135.493 161.051 1.00 19.78  ? 236 SER C OG  1 
ATOM   7341  N N   . TRP C 2 262 ? 140.141 137.380 163.679 1.00 21.10  ? 237 TRP C N   1 
ATOM   7342  C CA  . TRP C 2 262 ? 140.880 137.629 164.909 1.00 19.53  ? 237 TRP C CA  1 
ATOM   7343  C C   . TRP C 2 262 ? 140.024 138.268 165.990 1.00 25.02  ? 237 TRP C C   1 
ATOM   7344  O O   . TRP C 2 262 ? 140.459 138.321 167.144 1.00 34.73  ? 237 TRP C O   1 
ATOM   7345  C CB  . TRP C 2 262 ? 142.095 138.517 164.629 1.00 17.63  ? 237 TRP C CB  1 
ATOM   7346  C CG  . TRP C 2 262 ? 142.962 138.018 163.516 1.00 21.48  ? 237 TRP C CG  1 
ATOM   7347  C CD1 . TRP C 2 262 ? 143.069 136.733 163.075 1.00 22.28  ? 237 TRP C CD1 1 
ATOM   7348  C CD2 . TRP C 2 262 ? 143.832 138.800 162.691 1.00 25.09  ? 237 TRP C CD2 1 
ATOM   7349  N NE1 . TRP C 2 262 ? 143.958 136.664 162.031 1.00 26.19  ? 237 TRP C NE1 1 
ATOM   7350  C CE2 . TRP C 2 262 ? 144.440 137.920 161.775 1.00 25.03  ? 237 TRP C CE2 1 
ATOM   7351  C CE3 . TRP C 2 262 ? 144.158 140.158 162.639 1.00 24.15  ? 237 TRP C CE3 1 
ATOM   7352  C CZ2 . TRP C 2 262 ? 145.355 138.354 160.820 1.00 22.88  ? 237 TRP C CZ2 1 
ATOM   7353  C CZ3 . TRP C 2 262 ? 145.067 140.586 161.689 1.00 20.99  ? 237 TRP C CZ3 1 
ATOM   7354  C CH2 . TRP C 2 262 ? 145.654 139.688 160.794 1.00 22.52  ? 237 TRP C CH2 1 
ATOM   7355  N N   . VAL C 2 263 ? 138.832 138.766 165.647 1.00 22.84  ? 238 VAL C N   1 
ATOM   7356  C CA  . VAL C 2 263 ? 137.920 139.278 166.662 1.00 22.60  ? 238 VAL C CA  1 
ATOM   7357  C C   . VAL C 2 263 ? 137.566 138.181 167.656 1.00 24.29  ? 238 VAL C C   1 
ATOM   7358  O O   . VAL C 2 263 ? 137.228 138.469 168.810 1.00 29.48  ? 238 VAL C O   1 
ATOM   7359  C CB  . VAL C 2 263 ? 136.667 139.877 165.978 1.00 22.25  ? 238 VAL C CB  1 
ATOM   7360  C CG1 . VAL C 2 263 ? 135.512 140.048 166.954 1.00 19.81  ? 238 VAL C CG1 1 
ATOM   7361  C CG2 . VAL C 2 263 ? 137.009 141.206 165.328 1.00 23.33  ? 238 VAL C CG2 1 
ATOM   7362  N N   . SER C 2 264 ? 137.697 136.916 167.248 1.00 19.43  ? 239 SER C N   1 
ATOM   7363  C CA  . SER C 2 264 ? 137.432 135.806 168.154 1.00 21.12  ? 239 SER C CA  1 
ATOM   7364  C C   . SER C 2 264 ? 138.376 135.837 169.347 1.00 24.15  ? 239 SER C C   1 
ATOM   7365  O O   . SER C 2 264 ? 137.979 135.515 170.472 1.00 33.56  ? 239 SER C O   1 
ATOM   7366  C CB  . SER C 2 264 ? 137.561 134.482 167.401 1.00 21.99  ? 239 SER C CB  1 
ATOM   7367  O OG  . SER C 2 264 ? 137.282 133.378 168.244 1.00 22.39  ? 239 SER C OG  1 
ATOM   7368  N N   . PHE C 2 265 ? 139.632 136.222 169.118 1.00 22.06  ? 240 PHE C N   1 
ATOM   7369  C CA  . PHE C 2 265 ? 140.634 136.201 170.176 1.00 24.28  ? 240 PHE C CA  1 
ATOM   7370  C C   . PHE C 2 265 ? 140.317 137.184 171.295 1.00 27.00  ? 240 PHE C C   1 
ATOM   7371  O O   . PHE C 2 265 ? 140.866 137.053 172.394 1.00 33.27  ? 240 PHE C O   1 
ATOM   7372  C CB  . PHE C 2 265 ? 142.011 136.477 169.576 1.00 28.27  ? 240 PHE C CB  1 
ATOM   7373  C CG  . PHE C 2 265 ? 142.352 135.578 168.420 1.00 28.92  ? 240 PHE C CG  1 
ATOM   7374  C CD1 . PHE C 2 265 ? 141.956 134.252 168.418 1.00 27.24  ? 240 PHE C CD1 1 
ATOM   7375  C CD2 . PHE C 2 265 ? 143.043 136.064 167.325 1.00 30.27  ? 240 PHE C CD2 1 
ATOM   7376  C CE1 . PHE C 2 265 ? 142.260 133.425 167.357 1.00 24.85  ? 240 PHE C CE1 1 
ATOM   7377  C CE2 . PHE C 2 265 ? 143.346 135.239 166.259 1.00 25.63  ? 240 PHE C CE2 1 
ATOM   7378  C CZ  . PHE C 2 265 ? 142.953 133.919 166.276 1.00 23.58  ? 240 PHE C CZ  1 
ATOM   7379  N N   . TRP C 2 266 ? 139.455 138.167 171.042 1.00 25.93  ? 241 TRP C N   1 
ATOM   7380  C CA  . TRP C 2 266 ? 139.107 139.187 172.021 1.00 31.56  ? 241 TRP C CA  1 
ATOM   7381  C C   . TRP C 2 266 ? 137.760 138.924 172.682 1.00 30.93  ? 241 TRP C C   1 
ATOM   7382  O O   . TRP C 2 266 ? 137.275 139.771 173.439 1.00 26.84  ? 241 TRP C O   1 
ATOM   7383  C CB  . TRP C 2 266 ? 139.103 140.572 171.368 1.00 33.82  ? 241 TRP C CB  1 
ATOM   7384  C CG  . TRP C 2 266 ? 140.373 140.919 170.654 1.00 36.66  ? 241 TRP C CG  1 
ATOM   7385  C CD1 . TRP C 2 266 ? 140.738 140.538 169.396 1.00 37.40  ? 241 TRP C CD1 1 
ATOM   7386  C CD2 . TRP C 2 266 ? 141.442 141.730 171.152 1.00 40.33  ? 241 TRP C CD2 1 
ATOM   7387  N NE1 . TRP C 2 266 ? 141.971 141.057 169.082 1.00 37.21  ? 241 TRP C NE1 1 
ATOM   7388  C CE2 . TRP C 2 266 ? 142.425 141.792 170.145 1.00 42.14  ? 241 TRP C CE2 1 
ATOM   7389  C CE3 . TRP C 2 266 ? 141.665 142.408 172.354 1.00 38.65  ? 241 TRP C CE3 1 
ATOM   7390  C CZ2 . TRP C 2 266 ? 143.610 142.505 170.302 1.00 43.67  ? 241 TRP C CZ2 1 
ATOM   7391  C CZ3 . TRP C 2 266 ? 142.842 143.113 172.509 1.00 45.38  ? 241 TRP C CZ3 1 
ATOM   7392  C CH2 . TRP C 2 266 ? 143.800 143.157 171.489 1.00 43.62  ? 241 TRP C CH2 1 
ATOM   7393  N N   . ILE C 2 267 ? 137.151 137.772 172.419 1.00 32.48  ? 242 ILE C N   1 
ATOM   7394  C CA  . ILE C 2 267 ? 135.885 137.397 173.022 1.00 29.93  ? 242 ILE C CA  1 
ATOM   7395  C C   . ILE C 2 267 ? 136.157 136.383 174.126 1.00 31.28  ? 242 ILE C C   1 
ATOM   7396  O O   . ILE C 2 267 ? 137.197 135.720 174.156 1.00 32.35  ? 242 ILE C O   1 
ATOM   7397  C CB  . ILE C 2 267 ? 134.916 136.838 171.948 1.00 23.46  ? 242 ILE C CB  1 
ATOM   7398  C CG1 . ILE C 2 267 ? 134.746 137.851 170.818 1.00 19.08  ? 242 ILE C CG1 1 
ATOM   7399  C CG2 . ILE C 2 267 ? 133.546 136.528 172.523 1.00 27.25  ? 242 ILE C CG2 1 
ATOM   7400  C CD1 . ILE C 2 267 ? 134.076 137.287 169.592 1.00 18.16  ? 242 ILE C CD1 1 
ATOM   7401  N N   . ASN C 2 268 ? 135.214 136.272 175.061 1.00 32.84  ? 243 ASN C N   1 
ATOM   7402  C CA  . ASN C 2 268 ? 135.370 135.371 176.194 1.00 38.48  ? 243 ASN C CA  1 
ATOM   7403  C C   . ASN C 2 268 ? 135.535 133.931 175.724 1.00 42.90  ? 243 ASN C C   1 
ATOM   7404  O O   . ASN C 2 268 ? 134.958 133.512 174.718 1.00 41.11  ? 243 ASN C O   1 
ATOM   7405  C CB  . ASN C 2 268 ? 134.163 135.473 177.126 1.00 43.02  ? 243 ASN C CB  1 
ATOM   7406  C CG  . ASN C 2 268 ? 133.834 136.901 177.495 1.00 50.41  ? 243 ASN C CG  1 
ATOM   7407  O OD1 . ASN C 2 268 ? 134.704 137.658 177.922 1.00 58.70  ? 243 ASN C OD1 1 
ATOM   7408  N ND2 . ASN C 2 268 ? 132.572 137.279 177.332 1.00 51.21  ? 243 ASN C ND2 1 
ATOM   7409  N N   . TYR C 2 269 ? 136.334 133.167 176.473 1.00 46.52  ? 244 TYR C N   1 
ATOM   7410  C CA  . TYR C 2 269 ? 136.527 131.758 176.155 1.00 42.56  ? 244 TYR C CA  1 
ATOM   7411  C C   . TYR C 2 269 ? 135.249 130.949 176.317 1.00 47.31  ? 244 TYR C C   1 
ATOM   7412  O O   . TYR C 2 269 ? 135.132 129.873 175.722 1.00 48.81  ? 244 TYR C O   1 
ATOM   7413  C CB  . TYR C 2 269 ? 137.626 131.173 177.043 1.00 41.37  ? 244 TYR C CB  1 
ATOM   7414  C CG  . TYR C 2 269 ? 137.232 131.069 178.500 1.00 51.68  ? 244 TYR C CG  1 
ATOM   7415  C CD1 . TYR C 2 269 ? 137.460 132.121 179.375 1.00 57.45  ? 244 TYR C CD1 1 
ATOM   7416  C CD2 . TYR C 2 269 ? 136.637 129.918 179.002 1.00 55.38  ? 244 TYR C CD2 1 
ATOM   7417  C CE1 . TYR C 2 269 ? 137.101 132.034 180.708 1.00 66.86  ? 244 TYR C CE1 1 
ATOM   7418  C CE2 . TYR C 2 269 ? 136.275 129.822 180.331 1.00 59.23  ? 244 TYR C CE2 1 
ATOM   7419  C CZ  . TYR C 2 269 ? 136.510 130.881 181.179 1.00 70.40  ? 244 TYR C CZ  1 
ATOM   7420  O OH  . TYR C 2 269 ? 136.152 130.788 182.504 1.00 76.32  ? 244 TYR C OH  1 
ATOM   7421  N N   . ASP C 2 270 ? 134.297 131.439 177.105 1.00 49.64  ? 245 ASP C N   1 
ATOM   7422  C CA  . ASP C 2 270 ? 133.051 130.737 177.372 1.00 46.79  ? 245 ASP C CA  1 
ATOM   7423  C C   . ASP C 2 270 ? 131.926 131.144 176.431 1.00 47.64  ? 245 ASP C C   1 
ATOM   7424  O O   . ASP C 2 270 ? 130.832 130.578 176.518 1.00 53.07  ? 245 ASP C O   1 
ATOM   7425  C CB  . ASP C 2 270 ? 132.621 130.974 178.823 1.00 47.51  ? 245 ASP C CB  1 
ATOM   7426  C CG  . ASP C 2 270 ? 132.519 132.448 179.168 1.00 52.26  ? 245 ASP C CG  1 
ATOM   7427  O OD1 . ASP C 2 270 ? 131.562 133.106 178.711 1.00 44.06  ? 245 ASP C OD1 1 
ATOM   7428  O OD2 . ASP C 2 270 ? 133.401 132.952 179.894 1.00 59.32  ? 245 ASP C OD2 1 
ATOM   7429  N N   . ALA C 2 271 ? 132.163 132.109 175.542 1.00 40.71  ? 246 ALA C N   1 
ATOM   7430  C CA  . ALA C 2 271 ? 131.184 132.490 174.526 1.00 35.30  ? 246 ALA C CA  1 
ATOM   7431  C C   . ALA C 2 271 ? 131.274 131.560 173.314 1.00 22.82  ? 246 ALA C C   1 
ATOM   7432  O O   . ALA C 2 271 ? 131.613 131.962 172.202 1.00 21.85  ? 246 ALA C O   1 
ATOM   7433  C CB  . ALA C 2 271 ? 131.384 133.945 174.124 1.00 34.71  ? 246 ALA C CB  1 
ATOM   7434  N N   . SER C 2 272 ? 130.965 130.284 173.557 1.00 24.34  ? 247 SER C N   1 
ATOM   7435  C CA  . SER C 2 272 ? 131.162 129.275 172.522 1.00 27.44  ? 247 SER C CA  1 
ATOM   7436  C C   . SER C 2 272 ? 130.307 129.564 171.298 1.00 24.05  ? 247 SER C C   1 
ATOM   7437  O O   . SER C 2 272 ? 130.786 129.475 170.163 1.00 24.77  ? 247 SER C O   1 
ATOM   7438  C CB  . SER C 2 272 ? 130.846 127.886 173.076 1.00 28.41  ? 247 SER C CB  1 
ATOM   7439  O OG  . SER C 2 272 ? 129.482 127.780 173.441 1.00 28.36  ? 247 SER C OG  1 
ATOM   7440  N N   . ALA C 2 273 ? 129.039 129.917 171.506 1.00 23.26  ? 248 ALA C N   1 
ATOM   7441  C CA  . ALA C 2 273 ? 128.161 130.187 170.375 1.00 23.31  ? 248 ALA C CA  1 
ATOM   7442  C C   . ALA C 2 273 ? 128.640 131.389 169.571 1.00 23.01  ? 248 ALA C C   1 
ATOM   7443  O O   . ALA C 2 273 ? 128.626 131.360 168.335 1.00 24.14  ? 248 ALA C O   1 
ATOM   7444  C CB  . ALA C 2 273 ? 126.729 130.403 170.864 1.00 23.43  ? 248 ALA C CB  1 
ATOM   7445  N N   . ALA C 2 274 ? 129.057 132.459 170.251 1.00 23.24  ? 249 ALA C N   1 
ATOM   7446  C CA  . ALA C 2 274 ? 129.554 133.639 169.549 1.00 19.78  ? 249 ALA C CA  1 
ATOM   7447  C C   . ALA C 2 274 ? 130.851 133.355 168.797 1.00 17.11  ? 249 ALA C C   1 
ATOM   7448  O O   . ALA C 2 274 ? 131.003 133.751 167.636 1.00 16.65  ? 249 ALA C O   1 
ATOM   7449  C CB  . ALA C 2 274 ? 129.748 134.789 170.536 1.00 19.24  ? 249 ALA C CB  1 
ATOM   7450  N N   . ARG C 2 275 ? 131.802 132.674 169.442 1.00 15.77  ? 250 ARG C N   1 
ATOM   7451  C CA  . ARG C 2 275 ? 133.109 132.467 168.825 1.00 14.74  ? 250 ARG C CA  1 
ATOM   7452  C C   . ARG C 2 275 ? 133.101 131.382 167.757 1.00 14.96  ? 250 ARG C C   1 
ATOM   7453  O O   . ARG C 2 275 ? 133.847 131.485 166.777 1.00 13.91  ? 250 ARG C O   1 
ATOM   7454  C CB  . ARG C 2 275 ? 134.160 132.139 169.885 1.00 19.85  ? 250 ARG C CB  1 
ATOM   7455  C CG  . ARG C 2 275 ? 134.456 133.283 170.831 1.00 19.83  ? 250 ARG C CG  1 
ATOM   7456  C CD  . ARG C 2 275 ? 135.675 132.993 171.687 1.00 20.39  ? 250 ARG C CD  1 
ATOM   7457  N NE  . ARG C 2 275 ? 136.868 132.741 170.889 1.00 21.71  ? 250 ARG C NE  1 
ATOM   7458  C CZ  . ARG C 2 275 ? 138.093 132.643 171.387 1.00 26.83  ? 250 ARG C CZ  1 
ATOM   7459  N NH1 . ARG C 2 275 ? 138.327 132.795 172.679 1.00 29.13  ? 250 ARG C NH1 1 
ATOM   7460  N NH2 . ARG C 2 275 ? 139.110 132.399 170.566 1.00 29.53  ? 250 ARG C NH2 1 
ATOM   7461  N N   . VAL C 2 276 ? 132.286 130.339 167.920 1.00 16.59  ? 251 VAL C N   1 
ATOM   7462  C CA  . VAL C 2 276 ? 132.173 129.337 166.865 1.00 14.32  ? 251 VAL C CA  1 
ATOM   7463  C C   . VAL C 2 276 ? 131.432 129.904 165.663 1.00 15.75  ? 251 VAL C C   1 
ATOM   7464  O O   . VAL C 2 276 ? 131.847 129.703 164.517 1.00 17.52  ? 251 VAL C O   1 
ATOM   7465  C CB  . VAL C 2 276 ? 131.499 128.062 167.399 1.00 12.80  ? 251 VAL C CB  1 
ATOM   7466  C CG1 . VAL C 2 276 ? 131.170 127.124 166.256 1.00 10.03  ? 251 VAL C CG1 1 
ATOM   7467  C CG2 . VAL C 2 276 ? 132.410 127.371 168.394 1.00 15.96  ? 251 VAL C CG2 1 
ATOM   7468  N N   . ALA C 2 277 ? 130.335 130.629 165.898 1.00 17.22  ? 252 ALA C N   1 
ATOM   7469  C CA  . ALA C 2 277 ? 129.594 131.210 164.784 1.00 12.71  ? 252 ALA C CA  1 
ATOM   7470  C C   . ALA C 2 277 ? 130.469 132.173 163.994 1.00 12.57  ? 252 ALA C C   1 
ATOM   7471  O O   . ALA C 2 277 ? 130.433 132.184 162.759 1.00 15.04  ? 252 ALA C O   1 
ATOM   7472  C CB  . ALA C 2 277 ? 128.337 131.916 165.289 1.00 13.32  ? 252 ALA C CB  1 
ATOM   7473  N N   . LEU C 2 278 ? 131.252 132.998 164.691 1.00 11.31  ? 253 LEU C N   1 
ATOM   7474  C CA  . LEU C 2 278 ? 132.183 133.895 164.015 1.00 12.92  ? 253 LEU C CA  1 
ATOM   7475  C C   . LEU C 2 278 ? 133.211 133.106 163.212 1.00 11.79  ? 253 LEU C C   1 
ATOM   7476  O O   . LEU C 2 278 ? 133.401 133.344 162.015 1.00 11.02  ? 253 LEU C O   1 
ATOM   7477  C CB  . LEU C 2 278 ? 132.870 134.798 165.043 1.00 11.52  ? 253 LEU C CB  1 
ATOM   7478  C CG  . LEU C 2 278 ? 133.398 136.189 164.670 1.00 8.45   ? 253 LEU C CG  1 
ATOM   7479  C CD1 . LEU C 2 278 ? 134.172 136.774 165.836 1.00 9.10   ? 253 LEU C CD1 1 
ATOM   7480  C CD2 . LEU C 2 278 ? 134.256 136.192 163.420 1.00 7.89   ? 253 LEU C CD2 1 
ATOM   7481  N N   . GLY C 2 279 ? 133.882 132.153 163.863 1.00 10.41  ? 254 GLY C N   1 
ATOM   7482  C CA  . GLY C 2 279 ? 134.945 131.413 163.201 1.00 9.96   ? 254 GLY C CA  1 
ATOM   7483  C C   . GLY C 2 279 ? 134.468 130.591 162.019 1.00 12.57  ? 254 GLY C C   1 
ATOM   7484  O O   . GLY C 2 279 ? 135.098 130.591 160.960 1.00 15.82  ? 254 GLY C O   1 
ATOM   7485  N N   . ILE C 2 280 ? 133.349 129.882 162.179 1.00 11.86  ? 255 ILE C N   1 
ATOM   7486  C CA  . ILE C 2 280 ? 132.884 129.013 161.102 1.00 9.44   ? 255 ILE C CA  1 
ATOM   7487  C C   . ILE C 2 280 ? 132.322 129.832 159.948 1.00 10.00  ? 255 ILE C C   1 
ATOM   7488  O O   . ILE C 2 280 ? 132.434 129.430 158.784 1.00 13.08  ? 255 ILE C O   1 
ATOM   7489  C CB  . ILE C 2 280 ? 131.863 127.985 161.627 1.00 6.29   ? 255 ILE C CB  1 
ATOM   7490  C CG1 . ILE C 2 280 ? 131.647 126.884 160.592 1.00 7.06   ? 255 ILE C CG1 1 
ATOM   7491  C CG2 . ILE C 2 280 ? 130.531 128.640 161.941 1.00 6.99   ? 255 ILE C CG2 1 
ATOM   7492  C CD1 . ILE C 2 280 ? 132.902 126.136 160.227 1.00 7.17   ? 255 ILE C CD1 1 
ATOM   7493  N N   . THR C 2 281 ? 131.714 130.985 160.234 1.00 9.96   ? 256 THR C N   1 
ATOM   7494  C CA  . THR C 2 281 ? 131.168 131.809 159.163 1.00 10.80  ? 256 THR C CA  1 
ATOM   7495  C C   . THR C 2 281 ? 132.262 132.542 158.395 1.00 13.44  ? 256 THR C C   1 
ATOM   7496  O O   . THR C 2 281 ? 132.105 132.784 157.193 1.00 15.55  ? 256 THR C O   1 
ATOM   7497  C CB  . THR C 2 281 ? 130.153 132.805 159.724 1.00 10.04  ? 256 THR C CB  1 
ATOM   7498  O OG1 . THR C 2 281 ? 129.194 132.103 160.522 1.00 10.58  ? 256 THR C OG1 1 
ATOM   7499  C CG2 . THR C 2 281 ? 129.419 133.507 158.596 1.00 8.26   ? 256 THR C CG2 1 
ATOM   7500  N N   . THR C 2 282 ? 133.376 132.887 159.049 1.00 12.59  ? 257 THR C N   1 
ATOM   7501  C CA  . THR C 2 282 ? 134.511 133.421 158.301 1.00 12.02  ? 257 THR C CA  1 
ATOM   7502  C C   . THR C 2 282 ? 135.063 132.374 157.346 1.00 14.34  ? 257 THR C C   1 
ATOM   7503  O O   . THR C 2 282 ? 135.454 132.697 156.219 1.00 17.66  ? 257 THR C O   1 
ATOM   7504  C CB  . THR C 2 282 ? 135.605 133.909 159.248 1.00 11.62  ? 257 THR C CB  1 
ATOM   7505  O OG1 . THR C 2 282 ? 135.964 132.860 160.155 1.00 10.96  ? 257 THR C OG1 1 
ATOM   7506  C CG2 . THR C 2 282 ? 135.134 135.123 160.027 1.00 13.26  ? 257 THR C CG2 1 
ATOM   7507  N N   . VAL C 2 283 ? 135.111 131.113 157.781 1.00 11.24  ? 258 VAL C N   1 
ATOM   7508  C CA  . VAL C 2 283 ? 135.539 130.044 156.885 1.00 10.49  ? 258 VAL C CA  1 
ATOM   7509  C C   . VAL C 2 283 ? 134.578 129.956 155.709 1.00 11.31  ? 258 VAL C C   1 
ATOM   7510  O O   . VAL C 2 283 ? 134.991 129.851 154.549 1.00 12.89  ? 258 VAL C O   1 
ATOM   7511  C CB  . VAL C 2 283 ? 135.642 128.708 157.641 1.00 8.08   ? 258 VAL C CB  1 
ATOM   7512  C CG1 . VAL C 2 283 ? 135.885 127.569 156.670 1.00 8.30   ? 258 VAL C CG1 1 
ATOM   7513  C CG2 . VAL C 2 283 ? 136.753 128.772 158.668 1.00 8.93   ? 258 VAL C CG2 1 
ATOM   7514  N N   . LEU C 2 284 ? 133.275 129.996 155.998 1.00 8.83   ? 259 LEU C N   1 
ATOM   7515  C CA  . LEU C 2 284 ? 132.283 129.980 154.931 1.00 8.46   ? 259 LEU C CA  1 
ATOM   7516  C C   . LEU C 2 284 ? 132.410 131.220 154.060 1.00 12.52  ? 259 LEU C C   1 
ATOM   7517  O O   . LEU C 2 284 ? 132.300 131.139 152.831 1.00 18.60  ? 259 LEU C O   1 
ATOM   7518  C CB  . LEU C 2 284 ? 130.877 129.882 155.516 1.00 6.54   ? 259 LEU C CB  1 
ATOM   7519  C CG  . LEU C 2 284 ? 129.741 130.026 154.502 1.00 6.92   ? 259 LEU C CG  1 
ATOM   7520  C CD1 . LEU C 2 284 ? 129.824 128.950 153.437 1.00 7.87   ? 259 LEU C CD1 1 
ATOM   7521  C CD2 . LEU C 2 284 ? 128.400 129.985 155.207 1.00 9.05   ? 259 LEU C CD2 1 
ATOM   7522  N N   . THR C 2 285 ? 132.633 132.382 154.681 1.00 11.81  ? 260 THR C N   1 
ATOM   7523  C CA  . THR C 2 285 ? 132.816 133.605 153.910 1.00 10.91  ? 260 THR C CA  1 
ATOM   7524  C C   . THR C 2 285 ? 134.051 133.499 153.030 1.00 12.91  ? 260 THR C C   1 
ATOM   7525  O O   . THR C 2 285 ? 134.032 133.912 151.865 1.00 13.74  ? 260 THR C O   1 
ATOM   7526  C CB  . THR C 2 285 ? 132.920 134.812 154.839 1.00 10.47  ? 260 THR C CB  1 
ATOM   7527  O OG1 . THR C 2 285 ? 131.762 134.867 155.681 1.00 14.45  ? 260 THR C OG1 1 
ATOM   7528  C CG2 . THR C 2 285 ? 132.996 136.088 154.029 1.00 11.19  ? 260 THR C CG2 1 
ATOM   7529  N N   . MET C 2 286 ? 135.140 132.947 153.574 1.00 11.48  ? 261 MET C N   1 
ATOM   7530  C CA  . MET C 2 286 ? 136.364 132.816 152.794 1.00 10.43  ? 261 MET C CA  1 
ATOM   7531  C C   . MET C 2 286 ? 136.157 131.865 151.625 1.00 13.99  ? 261 MET C C   1 
ATOM   7532  O O   . MET C 2 286 ? 136.640 132.122 150.517 1.00 18.03  ? 261 MET C O   1 
ATOM   7533  C CB  . MET C 2 286 ? 137.510 132.337 153.683 1.00 10.49  ? 261 MET C CB  1 
ATOM   7534  C CG  . MET C 2 286 ? 138.871 132.392 153.014 1.00 14.89  ? 261 MET C CG  1 
ATOM   7535  S SD  . MET C 2 286 ? 139.336 134.041 152.465 1.00 22.26  ? 261 MET C SD  1 
ATOM   7536  C CE  . MET C 2 286 ? 139.436 134.888 154.034 1.00 13.91  ? 261 MET C CE  1 
ATOM   7537  N N   . THR C 2 287 ? 135.454 130.753 151.854 1.00 13.38  ? 262 THR C N   1 
ATOM   7538  C CA  . THR C 2 287 ? 135.152 129.851 150.748 1.00 15.01  ? 262 THR C CA  1 
ATOM   7539  C C   . THR C 2 287 ? 134.267 130.544 149.721 1.00 18.75  ? 262 THR C C   1 
ATOM   7540  O O   . THR C 2 287 ? 134.459 130.374 148.512 1.00 20.76  ? 262 THR C O   1 
ATOM   7541  C CB  . THR C 2 287 ? 134.476 128.581 151.260 1.00 9.65   ? 262 THR C CB  1 
ATOM   7542  O OG1 . THR C 2 287 ? 133.334 128.932 152.048 1.00 15.91  ? 262 THR C OG1 1 
ATOM   7543  C CG2 . THR C 2 287 ? 135.435 127.770 152.103 1.00 8.70   ? 262 THR C CG2 1 
ATOM   7544  N N   . THR C 2 288 ? 133.289 131.326 150.185 1.00 17.45  ? 263 THR C N   1 
ATOM   7545  C CA  . THR C 2 288 ? 132.434 132.062 149.261 1.00 16.45  ? 263 THR C CA  1 
ATOM   7546  C C   . THR C 2 288 ? 133.266 133.004 148.406 1.00 18.67  ? 263 THR C C   1 
ATOM   7547  O O   . THR C 2 288 ? 133.094 133.072 147.183 1.00 23.20  ? 263 THR C O   1 
ATOM   7548  C CB  . THR C 2 288 ? 131.361 132.831 150.031 1.00 17.27  ? 263 THR C CB  1 
ATOM   7549  O OG1 . THR C 2 288 ? 130.605 131.920 150.836 1.00 21.77  ? 263 THR C OG1 1 
ATOM   7550  C CG2 . THR C 2 288 ? 130.426 133.543 149.071 1.00 19.52  ? 263 THR C CG2 1 
ATOM   7551  N N   . ILE C 2 289 ? 134.173 133.751 149.041 1.00 17.66  ? 264 ILE C N   1 
ATOM   7552  C CA  . ILE C 2 289 ? 135.073 134.626 148.297 1.00 19.12  ? 264 ILE C CA  1 
ATOM   7553  C C   . ILE C 2 289 ? 135.934 133.804 147.352 1.00 22.29  ? 264 ILE C C   1 
ATOM   7554  O O   . ILE C 2 289 ? 136.103 134.154 146.180 1.00 24.71  ? 264 ILE C O   1 
ATOM   7555  C CB  . ILE C 2 289 ? 135.928 135.474 149.257 1.00 13.39  ? 264 ILE C CB  1 
ATOM   7556  C CG1 . ILE C 2 289 ? 135.044 136.433 150.053 1.00 9.99   ? 264 ILE C CG1 1 
ATOM   7557  C CG2 . ILE C 2 289 ? 136.988 136.242 148.492 1.00 11.55  ? 264 ILE C CG2 1 
ATOM   7558  C CD1 . ILE C 2 289 ? 135.747 137.082 151.218 1.00 10.25  ? 264 ILE C CD1 1 
ATOM   7559  N N   . ASN C 2 290 ? 136.474 132.685 147.841 1.00 21.14  ? 265 ASN C N   1 
ATOM   7560  C CA  . ASN C 2 290 ? 137.399 131.891 147.040 1.00 22.10  ? 265 ASN C CA  1 
ATOM   7561  C C   . ASN C 2 290 ? 136.683 131.198 145.889 1.00 24.77  ? 265 ASN C C   1 
ATOM   7562  O O   . ASN C 2 290 ? 137.171 131.208 144.754 1.00 24.41  ? 265 ASN C O   1 
ATOM   7563  C CB  . ASN C 2 290 ? 138.102 130.867 147.929 1.00 19.48  ? 265 ASN C CB  1 
ATOM   7564  C CG  . ASN C 2 290 ? 139.389 130.352 147.327 1.00 32.53  ? 265 ASN C CG  1 
ATOM   7565  O OD1 . ASN C 2 290 ? 139.551 130.320 146.107 1.00 34.70  ? 265 ASN C OD1 1 
ATOM   7566  N ND2 . ASN C 2 290 ? 140.317 129.942 148.183 1.00 35.19  ? 265 ASN C ND2 1 
ATOM   7567  N N   . THR C 2 291 ? 135.526 130.588 146.159 1.00 24.94  ? 266 THR C N   1 
ATOM   7568  C CA  . THR C 2 291 ? 134.847 129.824 145.118 1.00 24.67  ? 266 THR C CA  1 
ATOM   7569  C C   . THR C 2 291 ? 134.250 130.746 144.064 1.00 28.15  ? 266 THR C C   1 
ATOM   7570  O O   . THR C 2 291 ? 134.300 130.443 142.867 1.00 33.51  ? 266 THR C O   1 
ATOM   7571  C CB  . THR C 2 291 ? 133.763 128.933 145.724 1.00 22.84  ? 266 THR C CB  1 
ATOM   7572  O OG1 . THR C 2 291 ? 132.851 129.734 146.485 1.00 23.83  ? 266 THR C OG1 1 
ATOM   7573  C CG2 . THR C 2 291 ? 134.379 127.869 146.616 1.00 23.24  ? 266 THR C CG2 1 
ATOM   7574  N N   . HIS C 2 292 ? 133.669 131.869 144.488 1.00 27.48  ? 267 HIS C N   1 
ATOM   7575  C CA  . HIS C 2 292 ? 133.046 132.771 143.530 1.00 29.59  ? 267 HIS C CA  1 
ATOM   7576  C C   . HIS C 2 292 ? 134.082 133.592 142.774 1.00 29.69  ? 267 HIS C C   1 
ATOM   7577  O O   . HIS C 2 292 ? 133.837 133.984 141.628 1.00 33.52  ? 267 HIS C O   1 
ATOM   7578  C CB  . HIS C 2 292 ? 132.054 133.686 144.245 1.00 31.74  ? 267 HIS C CB  1 
ATOM   7579  C CG  . HIS C 2 292 ? 130.725 133.046 144.499 1.00 33.93  ? 267 HIS C CG  1 
ATOM   7580  N ND1 . HIS C 2 292 ? 130.580 131.921 145.281 1.00 32.30  ? 267 HIS C ND1 1 
ATOM   7581  C CD2 . HIS C 2 292 ? 129.483 133.368 144.069 1.00 40.65  ? 267 HIS C CD2 1 
ATOM   7582  C CE1 . HIS C 2 292 ? 129.305 131.580 145.326 1.00 38.26  ? 267 HIS C CE1 1 
ATOM   7583  N NE2 . HIS C 2 292 ? 128.618 132.442 144.599 1.00 44.97  ? 267 HIS C NE2 1 
ATOM   7584  N N   . LEU C 2 293 ? 135.233 133.866 143.395 1.00 28.38  ? 268 LEU C N   1 
ATOM   7585  C CA  . LEU C 2 293 ? 136.334 134.485 142.665 1.00 32.62  ? 268 LEU C CA  1 
ATOM   7586  C C   . LEU C 2 293 ? 136.842 133.576 141.560 1.00 34.91  ? 268 LEU C C   1 
ATOM   7587  O O   . LEU C 2 293 ? 137.337 134.056 140.536 1.00 37.87  ? 268 LEU C O   1 
ATOM   7588  C CB  . LEU C 2 293 ? 137.472 134.839 143.616 1.00 26.64  ? 268 LEU C CB  1 
ATOM   7589  C CG  . LEU C 2 293 ? 138.495 135.818 143.061 1.00 26.44  ? 268 LEU C CG  1 
ATOM   7590  C CD1 . LEU C 2 293 ? 137.874 137.176 142.947 1.00 23.19  ? 268 LEU C CD1 1 
ATOM   7591  C CD2 . LEU C 2 293 ? 139.711 135.869 143.957 1.00 35.00  ? 268 LEU C CD2 1 
ATOM   7592  N N   . ARG C 2 294 ? 136.723 132.263 141.755 1.00 33.91  ? 269 ARG C N   1 
ATOM   7593  C CA  . ARG C 2 294 ? 137.120 131.314 140.726 1.00 29.60  ? 269 ARG C CA  1 
ATOM   7594  C C   . ARG C 2 294 ? 136.269 131.487 139.478 1.00 32.52  ? 269 ARG C C   1 
ATOM   7595  O O   . ARG C 2 294 ? 136.715 131.166 138.371 1.00 40.71  ? 269 ARG C O   1 
ATOM   7596  C CB  . ARG C 2 294 ? 137.035 129.894 141.286 1.00 31.74  ? 269 ARG C CB  1 
ATOM   7597  C CG  . ARG C 2 294 ? 137.577 128.795 140.398 1.00 33.39  ? 269 ARG C CG  1 
ATOM   7598  C CD  . ARG C 2 294 ? 137.337 127.449 141.062 1.00 33.77  ? 269 ARG C CD  1 
ATOM   7599  N NE  . ARG C 2 294 ? 137.968 126.347 140.346 1.00 42.30  ? 269 ARG C NE  1 
ATOM   7600  C CZ  . ARG C 2 294 ? 137.860 125.073 140.696 1.00 47.41  ? 269 ARG C CZ  1 
ATOM   7601  N NH1 . ARG C 2 294 ? 137.138 124.703 141.740 1.00 53.24  ? 269 ARG C NH1 1 
ATOM   7602  N NH2 . ARG C 2 294 ? 138.501 124.149 139.987 1.00 53.22  ? 269 ARG C NH2 1 
ATOM   7603  N N   . GLU C 2 295 ? 135.042 131.989 139.635 1.00 33.84  ? 270 GLU C N   1 
ATOM   7604  C CA  . GLU C 2 295 ? 134.146 132.167 138.502 1.00 40.60  ? 270 GLU C CA  1 
ATOM   7605  C C   . GLU C 2 295 ? 134.383 133.488 137.777 1.00 39.24  ? 270 GLU C C   1 
ATOM   7606  O O   . GLU C 2 295 ? 134.289 133.532 136.546 1.00 41.18  ? 270 GLU C O   1 
ATOM   7607  C CB  . GLU C 2 295 ? 132.690 132.087 138.963 1.00 38.01  ? 270 GLU C CB  1 
ATOM   7608  C CG  . GLU C 2 295 ? 132.389 130.913 139.874 1.00 38.89  ? 270 GLU C CG  1 
ATOM   7609  C CD  . GLU C 2 295 ? 130.939 130.878 140.310 1.00 50.89  ? 270 GLU C CD  1 
ATOM   7610  O OE1 . GLU C 2 295 ? 130.098 131.499 139.627 1.00 46.04  ? 270 GLU C OE1 1 
ATOM   7611  O OE2 . GLU C 2 295 ? 130.640 130.230 141.335 1.00 58.30  ? 270 GLU C OE2 1 
ATOM   7612  N N   . THR C 2 296 ? 134.687 134.576 138.497 1.00 34.33  ? 271 THR C N   1 
ATOM   7613  C CA  . THR C 2 296 ? 134.880 135.837 137.785 1.00 37.52  ? 271 THR C CA  1 
ATOM   7614  C C   . THR C 2 296 ? 136.231 135.841 137.087 1.00 40.96  ? 271 THR C C   1 
ATOM   7615  O O   . THR C 2 296 ? 136.364 136.355 135.971 1.00 44.98  ? 271 THR C O   1 
ATOM   7616  C CB  . THR C 2 296 ? 134.782 137.015 138.753 1.00 44.32  ? 271 THR C CB  1 
ATOM   7617  O OG1 . THR C 2 296 ? 135.856 136.945 139.698 1.00 41.33  ? 271 THR C OG1 1 
ATOM   7618  C CG2 . THR C 2 296 ? 133.468 136.971 139.505 1.00 40.96  ? 271 THR C CG2 1 
ATOM   7619  N N   . LEU C 2 297 ? 137.233 135.271 137.741 1.00 40.14  ? 272 LEU C N   1 
ATOM   7620  C CA  . LEU C 2 297 ? 138.582 135.138 137.231 1.00 39.16  ? 272 LEU C CA  1 
ATOM   7621  C C   . LEU C 2 297 ? 138.582 134.024 136.196 1.00 44.04  ? 272 LEU C C   1 
ATOM   7622  O O   . LEU C 2 297 ? 137.657 133.208 136.163 1.00 43.51  ? 272 LEU C O   1 
ATOM   7623  C CB  . LEU C 2 297 ? 139.571 134.845 138.354 1.00 32.36  ? 272 LEU C CB  1 
ATOM   7624  C CG  . LEU C 2 297 ? 139.745 135.916 139.426 1.00 28.00  ? 272 LEU C CG  1 
ATOM   7625  C CD1 . LEU C 2 297 ? 140.793 135.468 140.429 1.00 25.03  ? 272 LEU C CD1 1 
ATOM   7626  C CD2 . LEU C 2 297 ? 140.119 137.245 138.799 1.00 29.16  ? 272 LEU C CD2 1 
ATOM   7627  N N   . PRO C 2 298 ? 139.583 133.952 135.330 1.00 46.38  ? 273 PRO C N   1 
ATOM   7628  C CA  . PRO C 2 298 ? 139.497 133.010 134.217 1.00 49.51  ? 273 PRO C CA  1 
ATOM   7629  C C   . PRO C 2 298 ? 139.848 131.611 134.710 1.00 50.79  ? 273 PRO C C   1 
ATOM   7630  O O   . PRO C 2 298 ? 140.457 131.416 135.763 1.00 49.09  ? 273 PRO C O   1 
ATOM   7631  C CB  . PRO C 2 298 ? 140.516 133.556 133.219 1.00 49.30  ? 273 PRO C CB  1 
ATOM   7632  C CG  . PRO C 2 298 ? 141.533 134.191 134.068 1.00 48.11  ? 273 PRO C CG  1 
ATOM   7633  C CD  . PRO C 2 298 ? 140.795 134.788 135.233 1.00 39.57  ? 273 PRO C CD  1 
ATOM   7634  N N   . LYS C 2 299 ? 139.446 130.631 133.910 1.00 50.83  ? 274 LYS C N   1 
ATOM   7635  C CA  . LYS C 2 299 ? 139.886 129.246 134.020 1.00 52.54  ? 274 LYS C CA  1 
ATOM   7636  C C   . LYS C 2 299 ? 141.342 128.941 133.697 1.00 47.98  ? 274 LYS C C   1 
ATOM   7637  O O   . LYS C 2 299 ? 141.618 128.236 132.722 1.00 50.83  ? 274 LYS C O   1 
ATOM   7638  C CB  . LYS C 2 299 ? 138.996 128.373 133.131 1.00 61.73  ? 274 LYS C CB  1 
ATOM   7639  C CG  . LYS C 2 299 ? 137.570 128.234 133.637 1.00 63.18  ? 274 LYS C CG  1 
ATOM   7640  C CD  . LYS C 2 299 ? 136.771 127.259 132.786 1.00 72.34  ? 274 LYS C CD  1 
ATOM   7641  C CE  . LYS C 2 299 ? 135.314 127.212 133.223 1.00 71.20  ? 274 LYS C CE  1 
ATOM   7642  N NZ  . LYS C 2 299 ? 134.504 126.307 132.363 1.00 62.38  ? 274 LYS C NZ  1 
ATOM   7643  N N   . ILE C 2 300 ? 142.282 129.462 134.481 1.00 42.68  ? 275 ILE C N   1 
ATOM   7644  C CA  . ILE C 2 300 ? 143.687 129.098 134.322 1.00 37.19  ? 275 ILE C CA  1 
ATOM   7645  C C   . ILE C 2 300 ? 143.968 127.974 135.316 1.00 38.76  ? 275 ILE C C   1 
ATOM   7646  O O   . ILE C 2 300 ? 144.034 128.235 136.528 1.00 43.98  ? 275 ILE C O   1 
ATOM   7647  C CB  . ILE C 2 300 ? 144.623 130.284 134.582 1.00 34.75  ? 275 ILE C CB  1 
ATOM   7648  C CG1 . ILE C 2 300 ? 144.272 131.484 133.710 1.00 38.14  ? 275 ILE C CG1 1 
ATOM   7649  C CG2 . ILE C 2 300 ? 146.062 129.876 134.350 1.00 36.82  ? 275 ILE C CG2 1 
ATOM   7650  C CD1 . ILE C 2 300 ? 144.628 132.789 134.381 1.00 35.89  ? 275 ILE C CD1 1 
ATOM   7651  N N   . PRO C 2 301 ? 144.148 126.741 134.864 1.00 31.83  ? 276 PRO C N   1 
ATOM   7652  C CA  . PRO C 2 301 ? 144.236 125.589 135.778 1.00 27.35  ? 276 PRO C CA  1 
ATOM   7653  C C   . PRO C 2 301 ? 145.661 125.292 136.245 1.00 32.40  ? 276 PRO C C   1 
ATOM   7654  O O   . PRO C 2 301 ? 146.217 124.223 135.975 1.00 33.23  ? 276 PRO C O   1 
ATOM   7655  C CB  . PRO C 2 301 ? 143.650 124.459 134.927 1.00 25.21  ? 276 PRO C CB  1 
ATOM   7656  C CG  . PRO C 2 301 ? 144.020 124.835 133.542 1.00 37.29  ? 276 PRO C CG  1 
ATOM   7657  C CD  . PRO C 2 301 ? 143.978 126.325 133.464 1.00 35.24  ? 276 PRO C CD  1 
ATOM   7658  N N   . TYR C 2 302 ? 146.259 126.237 136.968 1.00 35.59  ? 277 TYR C N   1 
ATOM   7659  C CA  . TYR C 2 302 ? 147.442 125.934 137.764 1.00 31.15  ? 277 TYR C CA  1 
ATOM   7660  C C   . TYR C 2 302 ? 147.659 127.037 138.786 1.00 26.93  ? 277 TYR C C   1 
ATOM   7661  O O   . TYR C 2 302 ? 147.079 128.121 138.694 1.00 28.38  ? 277 TYR C O   1 
ATOM   7662  C CB  . TYR C 2 302 ? 148.692 125.738 136.897 1.00 30.94  ? 277 TYR C CB  1 
ATOM   7663  C CG  . TYR C 2 302 ? 149.030 126.881 135.971 1.00 31.28  ? 277 TYR C CG  1 
ATOM   7664  C CD1 . TYR C 2 302 ? 149.838 127.928 136.389 1.00 29.79  ? 277 TYR C CD1 1 
ATOM   7665  C CD2 . TYR C 2 302 ? 148.573 126.890 134.662 1.00 31.44  ? 277 TYR C CD2 1 
ATOM   7666  C CE1 . TYR C 2 302 ? 150.158 128.964 135.536 1.00 29.75  ? 277 TYR C CE1 1 
ATOM   7667  C CE2 . TYR C 2 302 ? 148.889 127.918 133.803 1.00 34.12  ? 277 TYR C CE2 1 
ATOM   7668  C CZ  . TYR C 2 302 ? 149.680 128.953 134.245 1.00 31.47  ? 277 TYR C CZ  1 
ATOM   7669  O OH  . TYR C 2 302 ? 149.995 129.979 133.386 1.00 35.06  ? 277 TYR C OH  1 
ATOM   7670  N N   . VAL C 2 303 ? 148.510 126.736 139.766 1.00 21.03  ? 278 VAL C N   1 
ATOM   7671  C CA  . VAL C 2 303 ? 148.658 127.595 140.933 1.00 21.29  ? 278 VAL C CA  1 
ATOM   7672  C C   . VAL C 2 303 ? 149.278 128.920 140.518 1.00 32.48  ? 278 VAL C C   1 
ATOM   7673  O O   . VAL C 2 303 ? 150.314 128.956 139.841 1.00 41.60  ? 278 VAL C O   1 
ATOM   7674  C CB  . VAL C 2 303 ? 149.504 126.896 142.006 1.00 19.50  ? 278 VAL C CB  1 
ATOM   7675  C CG1 . VAL C 2 303 ? 149.561 127.739 143.266 1.00 20.68  ? 278 VAL C CG1 1 
ATOM   7676  C CG2 . VAL C 2 303 ? 148.941 125.519 142.304 1.00 28.60  ? 278 VAL C CG2 1 
ATOM   7677  N N   . LYS C 2 304 ? 148.649 130.015 140.925 1.00 32.01  ? 279 LYS C N   1 
ATOM   7678  C CA  . LYS C 2 304 ? 149.093 131.363 140.608 1.00 22.06  ? 279 LYS C CA  1 
ATOM   7679  C C   . LYS C 2 304 ? 149.359 132.117 141.907 1.00 20.59  ? 279 LYS C C   1 
ATOM   7680  O O   . LYS C 2 304 ? 149.178 131.585 143.004 1.00 26.11  ? 279 LYS C O   1 
ATOM   7681  C CB  . LYS C 2 304 ? 148.042 132.081 139.759 1.00 19.42  ? 279 LYS C CB  1 
ATOM   7682  C CG  . LYS C 2 304 ? 147.678 131.340 138.488 1.00 21.59  ? 279 LYS C CG  1 
ATOM   7683  C CD  . LYS C 2 304 ? 146.528 132.010 137.769 1.00 26.96  ? 279 LYS C CD  1 
ATOM   7684  C CE  . LYS C 2 304 ? 145.232 131.836 138.538 1.00 27.03  ? 279 LYS C CE  1 
ATOM   7685  N NZ  . LYS C 2 304 ? 144.885 130.402 138.728 1.00 25.38  ? 279 LYS C NZ  1 
ATOM   7686  N N   . ALA C 2 305 ? 149.803 133.369 141.779 1.00 20.27  ? 280 ALA C N   1 
ATOM   7687  C CA  . ALA C 2 305 ? 150.082 134.168 142.969 1.00 20.87  ? 280 ALA C CA  1 
ATOM   7688  C C   . ALA C 2 305 ? 148.809 134.432 143.762 1.00 20.00  ? 280 ALA C C   1 
ATOM   7689  O O   . ALA C 2 305 ? 148.834 134.453 144.997 1.00 25.29  ? 280 ALA C O   1 
ATOM   7690  C CB  . ALA C 2 305 ? 150.765 135.479 142.590 1.00 22.57  ? 280 ALA C CB  1 
ATOM   7691  N N   . ILE C 2 306 ? 147.689 134.648 143.069 1.00 17.97  ? 281 ILE C N   1 
ATOM   7692  C CA  . ILE C 2 306 ? 146.434 134.925 143.758 1.00 16.81  ? 281 ILE C CA  1 
ATOM   7693  C C   . ILE C 2 306 ? 145.956 133.686 144.506 1.00 17.08  ? 281 ILE C C   1 
ATOM   7694  O O   . ILE C 2 306 ? 145.399 133.786 145.605 1.00 17.22  ? 281 ILE C O   1 
ATOM   7695  C CB  . ILE C 2 306 ? 145.378 135.445 142.762 1.00 21.63  ? 281 ILE C CB  1 
ATOM   7696  C CG1 . ILE C 2 306 ? 144.123 135.926 143.495 1.00 21.50  ? 281 ILE C CG1 1 
ATOM   7697  C CG2 . ILE C 2 306 ? 145.041 134.399 141.706 1.00 20.52  ? 281 ILE C CG2 1 
ATOM   7698  C CD1 . ILE C 2 306 ? 144.361 137.097 144.415 1.00 23.68  ? 281 ILE C CD1 1 
ATOM   7699  N N   . ASP C 2 307 ? 146.154 132.502 143.919 1.00 20.67  ? 282 ASP C N   1 
ATOM   7700  C CA  . ASP C 2 307 ? 145.753 131.269 144.586 1.00 19.42  ? 282 ASP C CA  1 
ATOM   7701  C C   . ASP C 2 307 ? 146.509 131.086 145.895 1.00 18.00  ? 282 ASP C C   1 
ATOM   7702  O O   . ASP C 2 307 ? 145.933 130.649 146.897 1.00 20.63  ? 282 ASP C O   1 
ATOM   7703  C CB  . ASP C 2 307 ? 145.966 130.073 143.659 1.00 20.99  ? 282 ASP C CB  1 
ATOM   7704  C CG  . ASP C 2 307 ? 145.169 130.187 142.373 1.00 32.62  ? 282 ASP C CG  1 
ATOM   7705  O OD1 . ASP C 2 307 ? 144.092 130.817 142.395 1.00 33.17  ? 282 ASP C OD1 1 
ATOM   7706  O OD2 . ASP C 2 307 ? 145.615 129.646 141.341 1.00 40.87  ? 282 ASP C OD2 1 
ATOM   7707  N N   . MET C 2 308 ? 147.806 131.405 145.901 1.00 18.38  ? 283 MET C N   1 
ATOM   7708  C CA  . MET C 2 308 ? 148.601 131.241 147.113 1.00 17.89  ? 283 MET C CA  1 
ATOM   7709  C C   . MET C 2 308 ? 148.158 132.201 148.207 1.00 18.66  ? 283 MET C C   1 
ATOM   7710  O O   . MET C 2 308 ? 148.250 131.869 149.393 1.00 23.24  ? 283 MET C O   1 
ATOM   7711  C CB  . MET C 2 308 ? 150.085 131.432 146.807 1.00 19.26  ? 283 MET C CB  1 
ATOM   7712  C CG  . MET C 2 308 ? 150.660 130.386 145.873 1.00 24.95  ? 283 MET C CG  1 
ATOM   7713  S SD  . MET C 2 308 ? 150.556 128.727 146.568 1.00 61.63  ? 283 MET C SD  1 
ATOM   7714  C CE  . MET C 2 308 ? 151.669 128.875 147.960 1.00 44.18  ? 283 MET C CE  1 
ATOM   7715  N N   . TYR C 2 309 ? 147.679 133.391 147.838 1.00 18.29  ? 284 TYR C N   1 
ATOM   7716  C CA  . TYR C 2 309 ? 147.227 134.333 148.854 1.00 17.53  ? 284 TYR C CA  1 
ATOM   7717  C C   . TYR C 2 309 ? 145.884 133.901 149.425 1.00 17.86  ? 284 TYR C C   1 
ATOM   7718  O O   . TYR C 2 309 ? 145.671 133.961 150.641 1.00 18.72  ? 284 TYR C O   1 
ATOM   7719  C CB  . TYR C 2 309 ? 147.141 135.743 148.275 1.00 18.96  ? 284 TYR C CB  1 
ATOM   7720  C CG  . TYR C 2 309 ? 147.107 136.820 149.334 1.00 18.57  ? 284 TYR C CG  1 
ATOM   7721  C CD1 . TYR C 2 309 ? 148.283 137.336 149.857 1.00 19.31  ? 284 TYR C CD1 1 
ATOM   7722  C CD2 . TYR C 2 309 ? 145.903 137.318 149.811 1.00 15.84  ? 284 TYR C CD2 1 
ATOM   7723  C CE1 . TYR C 2 309 ? 148.263 138.314 150.824 1.00 17.00  ? 284 TYR C CE1 1 
ATOM   7724  C CE2 . TYR C 2 309 ? 145.874 138.300 150.780 1.00 15.42  ? 284 TYR C CE2 1 
ATOM   7725  C CZ  . TYR C 2 309 ? 147.059 138.794 151.281 1.00 15.33  ? 284 TYR C CZ  1 
ATOM   7726  O OH  . TYR C 2 309 ? 147.045 139.771 152.245 1.00 18.69  ? 284 TYR C OH  1 
ATOM   7727  N N   . LEU C 2 310 ? 144.966 133.465 148.561 1.00 20.05  ? 285 LEU C N   1 
ATOM   7728  C CA  . LEU C 2 310 ? 143.666 133.009 149.037 1.00 17.54  ? 285 LEU C CA  1 
ATOM   7729  C C   . LEU C 2 310 ? 143.823 131.756 149.884 1.00 18.18  ? 285 LEU C C   1 
ATOM   7730  O O   . LEU C 2 310 ? 143.153 131.599 150.911 1.00 17.65  ? 285 LEU C O   1 
ATOM   7731  C CB  . LEU C 2 310 ? 142.740 132.737 147.853 1.00 18.12  ? 285 LEU C CB  1 
ATOM   7732  C CG  . LEU C 2 310 ? 142.326 133.916 146.975 1.00 17.13  ? 285 LEU C CG  1 
ATOM   7733  C CD1 . LEU C 2 310 ? 141.452 133.422 145.842 1.00 18.06  ? 285 LEU C CD1 1 
ATOM   7734  C CD2 . LEU C 2 310 ? 141.600 134.971 147.790 1.00 17.95  ? 285 LEU C CD2 1 
ATOM   7735  N N   . MET C 2 311 ? 144.704 130.849 149.459 1.00 20.06  ? 286 MET C N   1 
ATOM   7736  C CA  . MET C 2 311 ? 144.987 129.656 150.244 1.00 17.43  ? 286 MET C CA  1 
ATOM   7737  C C   . MET C 2 311 ? 145.692 130.004 151.548 1.00 16.31  ? 286 MET C C   1 
ATOM   7738  O O   . MET C 2 311 ? 145.473 129.341 152.567 1.00 17.59  ? 286 MET C O   1 
ATOM   7739  C CB  . MET C 2 311 ? 145.842 128.691 149.422 1.00 15.11  ? 286 MET C CB  1 
ATOM   7740  C CG  . MET C 2 311 ? 145.922 127.270 149.949 1.00 17.43  ? 286 MET C CG  1 
ATOM   7741  S SD  . MET C 2 311 ? 144.328 126.430 149.972 1.00 44.44  ? 286 MET C SD  1 
ATOM   7742  C CE  . MET C 2 311 ? 143.864 126.627 151.684 1.00 31.77  ? 286 MET C CE  1 
ATOM   7743  N N   . GLY C 2 312 ? 146.548 131.027 151.530 1.00 16.03  ? 287 GLY C N   1 
ATOM   7744  C CA  . GLY C 2 312 ? 147.163 131.491 152.764 1.00 16.24  ? 287 GLY C CA  1 
ATOM   7745  C C   . GLY C 2 312 ? 146.157 132.036 153.759 1.00 17.39  ? 287 GLY C C   1 
ATOM   7746  O O   . GLY C 2 312 ? 146.213 131.729 154.952 1.00 20.99  ? 287 GLY C O   1 
ATOM   7747  N N   . CYS C 2 313 ? 145.223 132.861 153.281 1.00 17.48  ? 288 CYS C N   1 
ATOM   7748  C CA  . CYS C 2 313 ? 144.206 133.419 154.167 1.00 13.96  ? 288 CYS C CA  1 
ATOM   7749  C C   . CYS C 2 313 ? 143.221 132.361 154.645 1.00 14.86  ? 288 CYS C C   1 
ATOM   7750  O O   . CYS C 2 313 ? 142.725 132.448 155.773 1.00 16.30  ? 288 CYS C O   1 
ATOM   7751  C CB  . CYS C 2 313 ? 143.459 134.553 153.466 1.00 14.34  ? 288 CYS C CB  1 
ATOM   7752  S SG  . CYS C 2 313 ? 144.460 136.015 153.130 1.00 20.25  ? 288 CYS C SG  1 
ATOM   7753  N N   . PHE C 2 314 ? 142.924 131.361 153.812 1.00 16.74  ? 289 PHE C N   1 
ATOM   7754  C CA  . PHE C 2 314 ? 142.047 130.283 154.254 1.00 14.03  ? 289 PHE C CA  1 
ATOM   7755  C C   . PHE C 2 314 ? 142.689 129.485 155.379 1.00 13.52  ? 289 PHE C C   1 
ATOM   7756  O O   . PHE C 2 314 ? 141.999 129.044 156.304 1.00 15.59  ? 289 PHE C O   1 
ATOM   7757  C CB  . PHE C 2 314 ? 141.677 129.368 153.088 1.00 11.72  ? 289 PHE C CB  1 
ATOM   7758  C CG  . PHE C 2 314 ? 140.728 128.266 153.469 1.00 15.48  ? 289 PHE C CG  1 
ATOM   7759  C CD1 . PHE C 2 314 ? 139.362 128.485 153.454 1.00 14.45  ? 289 PHE C CD1 1 
ATOM   7760  C CD2 . PHE C 2 314 ? 141.193 127.022 153.856 1.00 16.83  ? 289 PHE C CD2 1 
ATOM   7761  C CE1 . PHE C 2 314 ? 138.480 127.484 153.806 1.00 11.46  ? 289 PHE C CE1 1 
ATOM   7762  C CE2 . PHE C 2 314 ? 140.313 126.017 154.212 1.00 17.07  ? 289 PHE C CE2 1 
ATOM   7763  C CZ  . PHE C 2 314 ? 138.956 126.250 154.186 1.00 12.11  ? 289 PHE C CZ  1 
ATOM   7764  N N   . VAL C 2 315 ? 144.003 129.264 155.307 1.00 14.33  ? 290 VAL C N   1 
ATOM   7765  C CA  . VAL C 2 315 ? 144.673 128.525 156.371 1.00 15.47  ? 290 VAL C CA  1 
ATOM   7766  C C   . VAL C 2 315 ? 144.651 129.330 157.665 1.00 14.90  ? 290 VAL C C   1 
ATOM   7767  O O   . VAL C 2 315 ? 144.492 128.770 158.757 1.00 16.04  ? 290 VAL C O   1 
ATOM   7768  C CB  . VAL C 2 315 ? 146.108 128.163 155.947 1.00 15.19  ? 290 VAL C CB  1 
ATOM   7769  C CG1 . VAL C 2 315 ? 146.912 127.674 157.137 1.00 10.34  ? 290 VAL C CG1 1 
ATOM   7770  C CG2 . VAL C 2 315 ? 146.086 127.110 154.855 1.00 16.35  ? 290 VAL C CG2 1 
ATOM   7771  N N   . PHE C 2 316 ? 144.802 130.653 157.567 1.00 12.75  ? 291 PHE C N   1 
ATOM   7772  C CA  . PHE C 2 316 ? 144.802 131.483 158.768 1.00 12.92  ? 291 PHE C CA  1 
ATOM   7773  C C   . PHE C 2 316 ? 143.447 131.447 159.465 1.00 15.47  ? 291 PHE C C   1 
ATOM   7774  O O   . PHE C 2 316 ? 143.379 131.323 160.693 1.00 20.72  ? 291 PHE C O   1 
ATOM   7775  C CB  . PHE C 2 316 ? 145.190 132.918 158.420 1.00 14.56  ? 291 PHE C CB  1 
ATOM   7776  C CG  . PHE C 2 316 ? 146.658 133.194 158.551 1.00 19.86  ? 291 PHE C CG  1 
ATOM   7777  C CD1 . PHE C 2 316 ? 147.204 133.535 159.773 1.00 22.94  ? 291 PHE C CD1 1 
ATOM   7778  C CD2 . PHE C 2 316 ? 147.491 133.113 157.449 1.00 19.36  ? 291 PHE C CD2 1 
ATOM   7779  C CE1 . PHE C 2 316 ? 148.554 133.788 159.895 1.00 28.29  ? 291 PHE C CE1 1 
ATOM   7780  C CE2 . PHE C 2 316 ? 148.839 133.365 157.564 1.00 19.11  ? 291 PHE C CE2 1 
ATOM   7781  C CZ  . PHE C 2 316 ? 149.373 133.703 158.788 1.00 25.61  ? 291 PHE C CZ  1 
ATOM   7782  N N   . VAL C 2 317 ? 142.358 131.568 158.702 1.00 13.90  ? 292 VAL C N   1 
ATOM   7783  C CA  . VAL C 2 317 ? 141.031 131.518 159.309 1.00 13.15  ? 292 VAL C CA  1 
ATOM   7784  C C   . VAL C 2 317 ? 140.712 130.104 159.776 1.00 14.80  ? 292 VAL C C   1 
ATOM   7785  O O   . VAL C 2 317 ? 139.988 129.918 160.761 1.00 18.40  ? 292 VAL C O   1 
ATOM   7786  C CB  . VAL C 2 317 ? 139.963 132.064 158.341 1.00 11.83  ? 292 VAL C CB  1 
ATOM   7787  C CG1 . VAL C 2 317 ? 140.363 133.438 157.841 1.00 15.72  ? 292 VAL C CG1 1 
ATOM   7788  C CG2 . VAL C 2 317 ? 139.750 131.124 157.171 1.00 10.85  ? 292 VAL C CG2 1 
ATOM   7789  N N   . PHE C 2 318 ? 141.224 129.089 159.075 1.00 12.03  ? 293 PHE C N   1 
ATOM   7790  C CA  . PHE C 2 318 ? 141.088 127.717 159.548 1.00 10.75  ? 293 PHE C CA  1 
ATOM   7791  C C   . PHE C 2 318 ? 141.764 127.542 160.901 1.00 13.13  ? 293 PHE C C   1 
ATOM   7792  O O   . PHE C 2 318 ? 141.223 126.879 161.793 1.00 16.56  ? 293 PHE C O   1 
ATOM   7793  C CB  . PHE C 2 318 ? 141.662 126.751 158.509 1.00 12.85  ? 293 PHE C CB  1 
ATOM   7794  C CG  . PHE C 2 318 ? 141.935 125.369 159.035 1.00 15.75  ? 293 PHE C CG  1 
ATOM   7795  C CD1 . PHE C 2 318 ? 140.943 124.404 159.029 1.00 10.66  ? 293 PHE C CD1 1 
ATOM   7796  C CD2 . PHE C 2 318 ? 143.194 125.023 159.502 1.00 16.25  ? 293 PHE C CD2 1 
ATOM   7797  C CE1 . PHE C 2 318 ? 141.193 123.132 159.502 1.00 9.16   ? 293 PHE C CE1 1 
ATOM   7798  C CE2 . PHE C 2 318 ? 143.448 123.753 159.975 1.00 13.18  ? 293 PHE C CE2 1 
ATOM   7799  C CZ  . PHE C 2 318 ? 142.447 122.806 159.974 1.00 10.81  ? 293 PHE C CZ  1 
ATOM   7800  N N   . LEU C 2 319 ? 142.953 128.127 161.070 1.00 12.53  ? 294 LEU C N   1 
ATOM   7801  C CA  . LEU C 2 319 ? 143.664 127.996 162.337 1.00 14.29  ? 294 LEU C CA  1 
ATOM   7802  C C   . LEU C 2 319 ? 142.996 128.795 163.448 1.00 18.32  ? 294 LEU C C   1 
ATOM   7803  O O   . LEU C 2 319 ? 143.058 128.393 164.615 1.00 24.90  ? 294 LEU C O   1 
ATOM   7804  C CB  . LEU C 2 319 ? 145.121 128.428 162.179 1.00 13.55  ? 294 LEU C CB  1 
ATOM   7805  C CG  . LEU C 2 319 ? 146.020 127.512 161.349 1.00 15.99  ? 294 LEU C CG  1 
ATOM   7806  C CD1 . LEU C 2 319 ? 147.397 128.126 161.177 1.00 23.15  ? 294 LEU C CD1 1 
ATOM   7807  C CD2 . LEU C 2 319 ? 146.124 126.146 162.001 1.00 14.95  ? 294 LEU C CD2 1 
ATOM   7808  N N   . ALA C 2 320 ? 142.362 129.922 163.118 1.00 16.49  ? 295 ALA C N   1 
ATOM   7809  C CA  . ALA C 2 320 ? 141.686 130.699 164.152 1.00 17.01  ? 295 ALA C CA  1 
ATOM   7810  C C   . ALA C 2 320 ? 140.520 129.919 164.744 1.00 21.26  ? 295 ALA C C   1 
ATOM   7811  O O   . ALA C 2 320 ? 140.286 129.967 165.956 1.00 26.93  ? 295 ALA C O   1 
ATOM   7812  C CB  . ALA C 2 320 ? 141.209 132.033 163.583 1.00 16.62  ? 295 ALA C CB  1 
ATOM   7813  N N   . LEU C 2 321 ? 139.772 129.203 163.902 1.00 20.50  ? 296 LEU C N   1 
ATOM   7814  C CA  . LEU C 2 321 ? 138.698 128.360 164.413 1.00 17.88  ? 296 LEU C CA  1 
ATOM   7815  C C   . LEU C 2 321 ? 139.265 127.203 165.224 1.00 20.56  ? 296 LEU C C   1 
ATOM   7816  O O   . LEU C 2 321 ? 138.717 126.841 166.272 1.00 27.07  ? 296 LEU C O   1 
ATOM   7817  C CB  . LEU C 2 321 ? 137.835 127.848 163.263 1.00 12.28  ? 296 LEU C CB  1 
ATOM   7818  C CG  . LEU C 2 321 ? 136.629 127.006 163.675 1.00 11.82  ? 296 LEU C CG  1 
ATOM   7819  C CD1 . LEU C 2 321 ? 135.830 127.712 164.756 1.00 12.68  ? 296 LEU C CD1 1 
ATOM   7820  C CD2 . LEU C 2 321 ? 135.755 126.719 162.471 1.00 12.94  ? 296 LEU C CD2 1 
ATOM   7821  N N   . LEU C 2 322 ? 140.364 126.613 164.749 1.00 18.43  ? 297 LEU C N   1 
ATOM   7822  C CA  . LEU C 2 322 ? 141.034 125.558 165.500 1.00 17.12  ? 297 LEU C CA  1 
ATOM   7823  C C   . LEU C 2 322 ? 141.617 126.093 166.801 1.00 20.31  ? 297 LEU C C   1 
ATOM   7824  O O   . LEU C 2 322 ? 141.742 125.354 167.785 1.00 27.19  ? 297 LEU C O   1 
ATOM   7825  C CB  . LEU C 2 322 ? 142.126 124.926 164.637 1.00 15.56  ? 297 LEU C CB  1 
ATOM   7826  C CG  . LEU C 2 322 ? 143.045 123.884 165.277 1.00 21.69  ? 297 LEU C CG  1 
ATOM   7827  C CD1 . LEU C 2 322 ? 142.254 122.673 165.744 1.00 25.35  ? 297 LEU C CD1 1 
ATOM   7828  C CD2 . LEU C 2 322 ? 144.140 123.473 164.305 1.00 19.24  ? 297 LEU C CD2 1 
ATOM   7829  N N   . GLU C 2 323 ? 141.979 127.379 166.826 1.00 19.02  ? 298 GLU C N   1 
ATOM   7830  C CA  . GLU C 2 323 ? 142.553 127.964 168.033 1.00 24.50  ? 298 GLU C CA  1 
ATOM   7831  C C   . GLU C 2 323 ? 141.555 127.946 169.183 1.00 29.04  ? 298 GLU C C   1 
ATOM   7832  O O   . GLU C 2 323 ? 141.926 127.676 170.331 1.00 34.41  ? 298 GLU C O   1 
ATOM   7833  C CB  . GLU C 2 323 ? 143.033 129.388 167.746 1.00 27.20  ? 298 GLU C CB  1 
ATOM   7834  C CG  . GLU C 2 323 ? 143.834 130.037 168.871 1.00 30.81  ? 298 GLU C CG  1 
ATOM   7835  C CD  . GLU C 2 323 ? 142.969 130.756 169.890 1.00 40.59  ? 298 GLU C CD  1 
ATOM   7836  O OE1 . GLU C 2 323 ? 141.739 130.828 169.693 1.00 40.72  ? 298 GLU C OE1 1 
ATOM   7837  O OE2 . GLU C 2 323 ? 143.524 131.255 170.892 1.00 45.38  ? 298 GLU C OE2 1 
ATOM   7838  N N   . TYR C 2 324 ? 140.285 128.240 168.900 1.00 25.86  ? 299 TYR C N   1 
ATOM   7839  C CA  . TYR C 2 324 ? 139.286 128.239 169.964 1.00 26.67  ? 299 TYR C CA  1 
ATOM   7840  C C   . TYR C 2 324 ? 138.963 126.824 170.419 1.00 29.32  ? 299 TYR C C   1 
ATOM   7841  O O   . TYR C 2 324 ? 138.710 126.591 171.606 1.00 37.36  ? 299 TYR C O   1 
ATOM   7842  C CB  . TYR C 2 324 ? 138.010 128.947 169.514 1.00 27.25  ? 299 TYR C CB  1 
ATOM   7843  C CG  . TYR C 2 324 ? 136.926 128.854 170.560 1.00 28.67  ? 299 TYR C CG  1 
ATOM   7844  C CD1 . TYR C 2 324 ? 137.057 129.512 171.773 1.00 31.82  ? 299 TYR C CD1 1 
ATOM   7845  C CD2 . TYR C 2 324 ? 135.791 128.084 170.351 1.00 23.55  ? 299 TYR C CD2 1 
ATOM   7846  C CE1 . TYR C 2 324 ? 136.088 129.422 172.740 1.00 30.35  ? 299 TYR C CE1 1 
ATOM   7847  C CE2 . TYR C 2 324 ? 134.813 127.988 171.317 1.00 27.41  ? 299 TYR C CE2 1 
ATOM   7848  C CZ  . TYR C 2 324 ? 134.968 128.661 172.510 1.00 29.38  ? 299 TYR C CZ  1 
ATOM   7849  O OH  . TYR C 2 324 ? 134.005 128.576 173.485 1.00 33.03  ? 299 TYR C OH  1 
ATOM   7850  N N   . ALA C 2 325 ? 138.954 125.869 169.488 1.00 25.01  ? 300 ALA C N   1 
ATOM   7851  C CA  . ALA C 2 325 ? 138.740 124.474 169.857 1.00 23.49  ? 300 ALA C CA  1 
ATOM   7852  C C   . ALA C 2 325 ? 139.771 124.004 170.870 1.00 31.86  ? 300 ALA C C   1 
ATOM   7853  O O   . ALA C 2 325 ? 139.434 123.299 171.828 1.00 42.02  ? 300 ALA C O   1 
ATOM   7854  C CB  . ALA C 2 325 ? 138.780 123.595 168.614 1.00 18.59  ? 300 ALA C CB  1 
ATOM   7855  N N   . PHE C 2 326 ? 141.037 124.372 170.669 1.00 30.05  ? 301 PHE C N   1 
ATOM   7856  C CA  . PHE C 2 326 ? 142.060 124.035 171.650 1.00 32.59  ? 301 PHE C CA  1 
ATOM   7857  C C   . PHE C 2 326 ? 141.792 124.732 172.978 1.00 39.98  ? 301 PHE C C   1 
ATOM   7858  O O   . PHE C 2 326 ? 141.994 124.143 174.045 1.00 45.13  ? 301 PHE C O   1 
ATOM   7859  C CB  . PHE C 2 326 ? 143.442 124.398 171.112 1.00 30.80  ? 301 PHE C CB  1 
ATOM   7860  C CG  . PHE C 2 326 ? 144.573 123.835 171.919 1.00 38.35  ? 301 PHE C CG  1 
ATOM   7861  C CD1 . PHE C 2 326 ? 144.903 122.493 171.828 1.00 43.94  ? 301 PHE C CD1 1 
ATOM   7862  C CD2 . PHE C 2 326 ? 145.312 124.645 172.763 1.00 42.86  ? 301 PHE C CD2 1 
ATOM   7863  C CE1 . PHE C 2 326 ? 145.945 121.969 172.569 1.00 52.45  ? 301 PHE C CE1 1 
ATOM   7864  C CE2 . PHE C 2 326 ? 146.356 124.127 173.506 1.00 48.27  ? 301 PHE C CE2 1 
ATOM   7865  C CZ  . PHE C 2 326 ? 146.673 122.787 173.408 1.00 53.19  ? 301 PHE C CZ  1 
ATOM   7866  N N   . VAL C 2 327 ? 141.335 125.987 172.932 1.00 38.73  ? 302 VAL C N   1 
ATOM   7867  C CA  . VAL C 2 327 ? 140.961 126.693 174.156 1.00 37.06  ? 302 VAL C CA  1 
ATOM   7868  C C   . VAL C 2 327 ? 139.734 126.048 174.789 1.00 37.72  ? 302 VAL C C   1 
ATOM   7869  O O   . VAL C 2 327 ? 139.686 125.819 176.003 1.00 37.29  ? 302 VAL C O   1 
ATOM   7870  C CB  . VAL C 2 327 ? 140.724 128.186 173.863 1.00 33.01  ? 302 VAL C CB  1 
ATOM   7871  C CG1 . VAL C 2 327 ? 139.943 128.834 174.992 1.00 38.65  ? 302 VAL C CG1 1 
ATOM   7872  C CG2 . VAL C 2 327 ? 142.044 128.898 173.659 1.00 45.46  ? 302 VAL C CG2 1 
ATOM   7873  N N   . ASN C 2 328 ? 138.720 125.750 173.973 1.00 38.46  ? 303 ASN C N   1 
ATOM   7874  C CA  . ASN C 2 328 ? 137.506 125.135 174.499 1.00 36.70  ? 303 ASN C CA  1 
ATOM   7875  C C   . ASN C 2 328 ? 137.795 123.760 175.087 1.00 39.91  ? 303 ASN C C   1 
ATOM   7876  O O   . ASN C 2 328 ? 137.250 123.398 176.136 1.00 47.39  ? 303 ASN C O   1 
ATOM   7877  C CB  . ASN C 2 328 ? 136.442 125.041 173.408 1.00 31.68  ? 303 ASN C CB  1 
ATOM   7878  C CG  . ASN C 2 328 ? 135.106 124.567 173.942 1.00 38.99  ? 303 ASN C CG  1 
ATOM   7879  O OD1 . ASN C 2 328 ? 134.876 123.369 174.092 1.00 48.49  ? 303 ASN C OD1 1 
ATOM   7880  N ND2 . ASN C 2 328 ? 134.219 125.509 174.239 1.00 37.36  ? 303 ASN C ND2 1 
ATOM   7881  N N   . TYR C 2 329 ? 138.644 122.973 174.422 1.00 39.30  ? 304 TYR C N   1 
ATOM   7882  C CA  . TYR C 2 329 ? 138.926 121.629 174.913 1.00 43.01  ? 304 TYR C CA  1 
ATOM   7883  C C   . TYR C 2 329 ? 139.786 121.673 176.167 1.00 50.87  ? 304 TYR C C   1 
ATOM   7884  O O   . TYR C 2 329 ? 139.520 120.948 177.132 1.00 59.74  ? 304 TYR C O   1 
ATOM   7885  C CB  . TYR C 2 329 ? 139.606 120.789 173.833 1.00 39.83  ? 304 TYR C CB  1 
ATOM   7886  C CG  . TYR C 2 329 ? 140.148 119.479 174.361 1.00 54.16  ? 304 TYR C CG  1 
ATOM   7887  C CD1 . TYR C 2 329 ? 139.315 118.384 174.541 1.00 58.85  ? 304 TYR C CD1 1 
ATOM   7888  C CD2 . TYR C 2 329 ? 141.493 119.339 174.681 1.00 55.18  ? 304 TYR C CD2 1 
ATOM   7889  C CE1 . TYR C 2 329 ? 139.804 117.188 175.027 1.00 55.61  ? 304 TYR C CE1 1 
ATOM   7890  C CE2 . TYR C 2 329 ? 141.990 118.147 175.167 1.00 55.36  ? 304 TYR C CE2 1 
ATOM   7891  C CZ  . TYR C 2 329 ? 141.142 117.075 175.337 1.00 60.62  ? 304 TYR C CZ  1 
ATOM   7892  O OH  . TYR C 2 329 ? 141.634 115.884 175.821 1.00 77.26  ? 304 TYR C OH  1 
ATOM   7893  N N   . ILE C 2 330 ? 140.829 122.506 176.170 1.00 44.95  ? 305 ILE C N   1 
ATOM   7894  C CA  . ILE C 2 330 ? 141.738 122.550 177.308 1.00 47.69  ? 305 ILE C CA  1 
ATOM   7895  C C   . ILE C 2 330 ? 141.038 123.061 178.561 1.00 49.80  ? 305 ILE C C   1 
ATOM   7896  O O   . ILE C 2 330 ? 141.557 122.891 179.670 1.00 56.92  ? 305 ILE C O   1 
ATOM   7897  C CB  . ILE C 2 330 ? 142.972 123.410 176.976 1.00 46.04  ? 305 ILE C CB  1 
ATOM   7898  C CG1 . ILE C 2 330 ? 144.145 123.048 177.886 1.00 50.39  ? 305 ILE C CG1 1 
ATOM   7899  C CG2 . ILE C 2 330 ? 142.647 124.885 177.117 1.00 52.58  ? 305 ILE C CG2 1 
ATOM   7900  C CD1 . ILE C 2 330 ? 145.408 123.824 177.587 1.00 51.29  ? 305 ILE C CD1 1 
ATOM   7901  N N   . PHE C 2 331 ? 139.865 123.679 178.418 1.00 48.66  ? 306 PHE C N   1 
ATOM   7902  C CA  . PHE C 2 331 ? 139.091 124.130 179.570 1.00 52.40  ? 306 PHE C CA  1 
ATOM   7903  C C   . PHE C 2 331 ? 138.078 123.078 180.018 1.00 49.27  ? 306 PHE C C   1 
ATOM   7904  O O   . PHE C 2 331 ? 138.149 122.583 181.146 1.00 52.06  ? 306 PHE C O   1 
ATOM   7905  C CB  . PHE C 2 331 ? 138.390 125.454 179.241 1.00 52.29  ? 306 PHE C CB  1 
ATOM   7906  C CG  . PHE C 2 331 ? 137.622 126.036 180.391 1.00 51.72  ? 306 PHE C CG  1 
ATOM   7907  C CD1 . PHE C 2 331 ? 138.254 126.839 181.324 1.00 55.30  ? 306 PHE C CD1 1 
ATOM   7908  C CD2 . PHE C 2 331 ? 136.266 125.793 180.533 1.00 48.99  ? 306 PHE C CD2 1 
ATOM   7909  C CE1 . PHE C 2 331 ? 137.553 127.378 182.383 1.00 54.87  ? 306 PHE C CE1 1 
ATOM   7910  C CE2 . PHE C 2 331 ? 135.559 126.331 181.591 1.00 51.67  ? 306 PHE C CE2 1 
ATOM   7911  C CZ  . PHE C 2 331 ? 136.203 127.124 182.516 1.00 54.29  ? 306 PHE C CZ  1 
ATOM   7912  N N   . PHE C 2 332 ? 137.135 122.719 179.143 1.00 49.64  ? 307 PHE C N   1 
ATOM   7913  C CA  . PHE C 2 332 ? 136.108 121.756 179.527 1.00 48.90  ? 307 PHE C CA  1 
ATOM   7914  C C   . PHE C 2 332 ? 136.623 120.323 179.531 1.00 52.30  ? 307 PHE C C   1 
ATOM   7915  O O   . PHE C 2 332 ? 136.175 119.515 180.352 1.00 52.67  ? 307 PHE C O   1 
ATOM   7916  C CB  . PHE C 2 332 ? 134.895 121.868 178.600 1.00 50.68  ? 307 PHE C CB  1 
ATOM   7917  C CG  . PHE C 2 332 ? 134.210 123.204 178.651 1.00 53.11  ? 307 PHE C CG  1 
ATOM   7918  C CD1 . PHE C 2 332 ? 133.394 123.535 179.719 1.00 55.41  ? 307 PHE C CD1 1 
ATOM   7919  C CD2 . PHE C 2 332 ? 134.376 124.125 177.633 1.00 52.90  ? 307 PHE C CD2 1 
ATOM   7920  C CE1 . PHE C 2 332 ? 132.759 124.761 179.772 1.00 55.80  ? 307 PHE C CE1 1 
ATOM   7921  C CE2 . PHE C 2 332 ? 133.743 125.353 177.682 1.00 51.56  ? 307 PHE C CE2 1 
ATOM   7922  C CZ  . PHE C 2 332 ? 132.934 125.670 178.752 1.00 51.96  ? 307 PHE C CZ  1 
ATOM   7923  N N   . GLY C 2 333 ? 137.552 119.984 178.639 1.00 49.32  ? 308 GLY C N   1 
ATOM   7924  C CA  . GLY C 2 333 ? 138.104 118.643 178.646 1.00 50.59  ? 308 GLY C CA  1 
ATOM   7925  C C   . GLY C 2 333 ? 139.197 118.403 179.662 1.00 57.87  ? 308 GLY C C   1 
ATOM   7926  O O   . GLY C 2 333 ? 139.619 117.255 179.833 1.00 69.22  ? 308 GLY C O   1 
ATOM   7927  N N   . ARG C 2 334 ? 139.652 119.447 180.347 1.00 53.67  ? 309 ARG C N   1 
ATOM   7928  C CA  . ARG C 2 334 ? 140.715 119.330 181.343 1.00 53.66  ? 309 ARG C CA  1 
ATOM   7929  C C   . ARG C 2 334 ? 140.500 120.337 182.466 1.00 53.54  ? 309 ARG C C   1 
ATOM   7930  O O   . ARG C 2 334 ? 141.265 121.290 182.613 1.00 54.84  ? 309 ARG C O   1 
ATOM   7931  C CB  . ARG C 2 334 ? 142.098 119.544 180.714 1.00 56.55  ? 309 ARG C CB  1 
ATOM   7932  C CG  . ARG C 2 334 ? 142.476 118.549 179.629 1.00 63.36  ? 309 ARG C CG  1 
ATOM   7933  C CD  . ARG C 2 334 ? 143.924 118.708 179.195 1.00 71.92  ? 309 ARG C CD  1 
ATOM   7934  N NE  . ARG C 2 334 ? 144.353 117.610 178.335 1.00 73.65  ? 309 ARG C NE  1 
ATOM   7935  C CZ  . ARG C 2 334 ? 145.592 117.441 177.897 1.00 73.26  ? 309 ARG C CZ  1 
ATOM   7936  N NH1 . ARG C 2 334 ? 146.560 118.283 178.218 1.00 67.04  ? 309 ARG C NH1 1 
ATOM   7937  N NH2 . ARG C 2 334 ? 145.867 116.401 177.116 1.00 74.84  ? 309 ARG C NH2 1 
ATOM   7938  N N   . ASP C 2 444 ? 146.748 129.858 181.770 1.00 61.86  ? 444 ASP C N   1 
ATOM   7939  C CA  . ASP C 2 444 ? 146.790 128.953 180.628 1.00 75.04  ? 444 ASP C CA  1 
ATOM   7940  C C   . ASP C 2 444 ? 145.778 129.361 179.565 1.00 71.25  ? 444 ASP C C   1 
ATOM   7941  O O   . ASP C 2 444 ? 146.150 129.717 178.447 1.00 74.48  ? 444 ASP C O   1 
ATOM   7942  C CB  . ASP C 2 444 ? 146.532 127.513 181.077 1.00 81.81  ? 444 ASP C CB  1 
ATOM   7943  C CG  . ASP C 2 444 ? 147.682 126.937 181.877 1.00 87.30  ? 444 ASP C CG  1 
ATOM   7944  O OD1 . ASP C 2 444 ? 148.619 127.695 182.203 1.00 87.31  ? 444 ASP C OD1 1 
ATOM   7945  O OD2 . ASP C 2 444 ? 147.650 125.726 182.183 1.00 85.43  ? 444 ASP C OD2 1 
ATOM   7946  N N   . VAL C 2 445 ? 144.493 129.300 179.924 1.00 69.62  ? 445 VAL C N   1 
ATOM   7947  C CA  . VAL C 2 445 ? 143.434 129.622 178.971 1.00 70.08  ? 445 VAL C CA  1 
ATOM   7948  C C   . VAL C 2 445 ? 143.555 131.068 178.509 1.00 70.76  ? 445 VAL C C   1 
ATOM   7949  O O   . VAL C 2 445 ? 143.444 131.367 177.313 1.00 63.67  ? 445 VAL C O   1 
ATOM   7950  C CB  . VAL C 2 445 ? 142.054 129.337 179.595 1.00 69.96  ? 445 VAL C CB  1 
ATOM   7951  C CG1 . VAL C 2 445 ? 140.956 130.054 178.824 1.00 60.35  ? 445 VAL C CG1 1 
ATOM   7952  C CG2 . VAL C 2 445 ? 141.794 127.840 179.643 1.00 64.11  ? 445 VAL C CG2 1 
ATOM   7953  N N   . ASN C 2 446 ? 143.789 131.987 179.448 1.00 70.77  ? 446 ASN C N   1 
ATOM   7954  C CA  . ASN C 2 446 ? 143.971 133.387 179.084 1.00 67.88  ? 446 ASN C CA  1 
ATOM   7955  C C   . ASN C 2 446 ? 145.257 133.589 178.291 1.00 69.44  ? 446 ASN C C   1 
ATOM   7956  O O   . ASN C 2 446 ? 145.338 134.485 177.443 1.00 68.80  ? 446 ASN C O   1 
ATOM   7957  C CB  . ASN C 2 446 ? 143.969 134.256 180.342 1.00 66.30  ? 446 ASN C CB  1 
ATOM   7958  C CG  . ASN C 2 446 ? 144.079 135.735 180.031 1.00 72.16  ? 446 ASN C CG  1 
ATOM   7959  O OD1 . ASN C 2 446 ? 143.074 136.413 179.826 1.00 71.19  ? 446 ASN C OD1 1 
ATOM   7960  N ND2 . ASN C 2 446 ? 145.305 136.245 180.002 1.00 75.64  ? 446 ASN C ND2 1 
ATOM   7961  N N   . ALA C 2 447 ? 146.277 132.769 178.560 1.00 71.21  ? 447 ALA C N   1 
ATOM   7962  C CA  . ALA C 2 447 ? 147.548 132.915 177.857 1.00 60.57  ? 447 ALA C CA  1 
ATOM   7963  C C   . ALA C 2 447 ? 147.402 132.616 176.370 1.00 52.15  ? 447 ALA C C   1 
ATOM   7964  O O   . ALA C 2 447 ? 147.960 133.331 175.530 1.00 52.34  ? 447 ALA C O   1 
ATOM   7965  C CB  . ALA C 2 447 ? 148.602 132.003 178.484 1.00 58.97  ? 447 ALA C CB  1 
ATOM   7966  N N   . ILE C 2 448 ? 146.664 131.559 176.026 1.00 52.94  ? 448 ILE C N   1 
ATOM   7967  C CA  . ILE C 2 448 ? 146.536 131.167 174.625 1.00 52.57  ? 448 ILE C CA  1 
ATOM   7968  C C   . ILE C 2 448 ? 145.859 132.269 173.822 1.00 50.42  ? 448 ILE C C   1 
ATOM   7969  O O   . ILE C 2 448 ? 146.275 132.589 172.702 1.00 51.93  ? 448 ILE C O   1 
ATOM   7970  C CB  . ILE C 2 448 ? 145.776 129.834 174.503 1.00 53.17  ? 448 ILE C CB  1 
ATOM   7971  C CG1 . ILE C 2 448 ? 146.538 128.714 175.210 1.00 59.32  ? 448 ILE C CG1 1 
ATOM   7972  C CG2 . ILE C 2 448 ? 145.579 129.470 173.042 1.00 42.59  ? 448 ILE C CG2 1 
ATOM   7973  C CD1 . ILE C 2 448 ? 145.839 127.374 175.149 1.00 56.04  ? 448 ILE C CD1 1 
ATOM   7974  N N   . ASP C 2 449 ? 144.797 132.860 174.376 1.00 49.40  ? 449 ASP C N   1 
ATOM   7975  C CA  . ASP C 2 449 ? 144.149 133.983 173.706 1.00 46.15  ? 449 ASP C CA  1 
ATOM   7976  C C   . ASP C 2 449 ? 145.075 135.189 173.613 1.00 46.00  ? 449 ASP C C   1 
ATOM   7977  O O   . ASP C 2 449 ? 145.137 135.850 172.571 1.00 45.49  ? 449 ASP C O   1 
ATOM   7978  C CB  . ASP C 2 449 ? 142.859 134.357 174.437 1.00 49.01  ? 449 ASP C CB  1 
ATOM   7979  C CG  . ASP C 2 449 ? 141.655 133.595 173.921 1.00 47.25  ? 449 ASP C CG  1 
ATOM   7980  O OD1 . ASP C 2 449 ? 141.790 132.886 172.903 1.00 42.84  ? 449 ASP C OD1 1 
ATOM   7981  O OD2 . ASP C 2 449 ? 140.573 133.709 174.533 1.00 46.26  ? 449 ASP C OD2 1 
ATOM   7982  N N   . ARG C 2 450 ? 145.806 135.490 174.690 1.00 49.52  ? 450 ARG C N   1 
ATOM   7983  C CA  . ARG C 2 450 ? 146.755 136.600 174.656 1.00 49.39  ? 450 ARG C CA  1 
ATOM   7984  C C   . ARG C 2 450 ? 147.824 136.386 173.591 1.00 50.24  ? 450 ARG C C   1 
ATOM   7985  O O   . ARG C 2 450 ? 148.133 137.296 172.815 1.00 49.32  ? 450 ARG C O   1 
ATOM   7986  C CB  . ARG C 2 450 ? 147.394 136.794 176.030 1.00 56.45  ? 450 ARG C CB  1 
ATOM   7987  C CG  . ARG C 2 450 ? 146.756 137.902 176.851 1.00 70.07  ? 450 ARG C CG  1 
ATOM   7988  C CD  . ARG C 2 450 ? 147.534 138.161 178.130 1.00 83.03  ? 450 ARG C CD  1 
ATOM   7989  N NE  . ARG C 2 450 ? 147.002 139.297 178.874 1.00 91.05  ? 450 ARG C NE  1 
ATOM   7990  C CZ  . ARG C 2 450 ? 147.501 139.743 180.019 1.00 98.61  ? 450 ARG C CZ  1 
ATOM   7991  N NH1 . ARG C 2 450 ? 148.551 139.171 180.585 1.00 95.39  ? 450 ARG C NH1 1 
ATOM   7992  N NH2 . ARG C 2 450 ? 146.931 140.788 180.612 1.00 108.41 ? 450 ARG C NH2 1 
ATOM   7993  N N   . TRP C 2 451 ? 148.403 135.185 173.540 1.00 54.54  ? 451 TRP C N   1 
ATOM   7994  C CA  . TRP C 2 451 ? 149.434 134.918 172.542 1.00 49.25  ? 451 TRP C CA  1 
ATOM   7995  C C   . TRP C 2 451 ? 148.856 134.877 171.136 1.00 39.28  ? 451 TRP C C   1 
ATOM   7996  O O   . TRP C 2 451 ? 149.534 135.260 170.177 1.00 36.07  ? 451 TRP C O   1 
ATOM   7997  C CB  . TRP C 2 451 ? 150.161 133.613 172.860 1.00 49.07  ? 451 TRP C CB  1 
ATOM   7998  C CG  . TRP C 2 451 ? 151.171 133.755 173.956 1.00 61.50  ? 451 TRP C CG  1 
ATOM   7999  C CD1 . TRP C 2 451 ? 151.063 133.295 175.237 1.00 70.42  ? 451 TRP C CD1 1 
ATOM   8000  C CD2 . TRP C 2 451 ? 152.439 134.414 173.872 1.00 65.12  ? 451 TRP C CD2 1 
ATOM   8001  N NE1 . TRP C 2 451 ? 152.189 133.622 175.953 1.00 74.77  ? 451 TRP C NE1 1 
ATOM   8002  C CE2 . TRP C 2 451 ? 153.049 134.310 175.138 1.00 73.80  ? 451 TRP C CE2 1 
ATOM   8003  C CE3 . TRP C 2 451 ? 153.119 135.080 172.849 1.00 60.13  ? 451 TRP C CE3 1 
ATOM   8004  C CZ2 . TRP C 2 451 ? 154.306 134.846 175.407 1.00 75.51  ? 451 TRP C CZ2 1 
ATOM   8005  C CZ3 . TRP C 2 451 ? 154.366 135.612 173.118 1.00 64.51  ? 451 TRP C CZ3 1 
ATOM   8006  C CH2 . TRP C 2 451 ? 154.947 135.492 174.386 1.00 70.71  ? 451 TRP C CH2 1 
ATOM   8007  N N   . SER C 2 452 ? 147.613 134.419 170.986 1.00 40.20  ? 452 SER C N   1 
ATOM   8008  C CA  . SER C 2 452 ? 147.011 134.416 169.660 1.00 38.96  ? 452 SER C CA  1 
ATOM   8009  C C   . SER C 2 452 ? 146.693 135.826 169.183 1.00 36.77  ? 452 SER C C   1 
ATOM   8010  O O   . SER C 2 452 ? 146.680 136.075 167.972 1.00 36.10  ? 452 SER C O   1 
ATOM   8011  C CB  . SER C 2 452 ? 145.743 133.561 169.659 1.00 42.14  ? 452 SER C CB  1 
ATOM   8012  O OG  . SER C 2 452 ? 146.022 132.236 170.079 1.00 44.97  ? 452 SER C OG  1 
ATOM   8013  N N   . ARG C 2 453 ? 146.408 136.749 170.108 1.00 37.51  ? 453 ARG C N   1 
ATOM   8014  C CA  . ARG C 2 453 ? 146.145 138.130 169.720 1.00 37.20  ? 453 ARG C CA  1 
ATOM   8015  C C   . ARG C 2 453 ? 147.351 138.780 169.056 1.00 43.80  ? 453 ARG C C   1 
ATOM   8016  O O   . ARG C 2 453 ? 147.188 139.770 168.335 1.00 47.32  ? 453 ARG C O   1 
ATOM   8017  C CB  . ARG C 2 453 ? 145.724 138.954 170.937 1.00 39.69  ? 453 ARG C CB  1 
ATOM   8018  C CG  . ARG C 2 453 ? 144.325 138.659 171.447 1.00 37.74  ? 453 ARG C CG  1 
ATOM   8019  C CD  . ARG C 2 453 ? 144.115 139.273 172.818 1.00 39.69  ? 453 ARG C CD  1 
ATOM   8020  N NE  . ARG C 2 453 ? 142.866 138.840 173.432 1.00 36.47  ? 453 ARG C NE  1 
ATOM   8021  C CZ  . ARG C 2 453 ? 142.540 139.067 174.697 1.00 40.20  ? 453 ARG C CZ  1 
ATOM   8022  N NH1 . ARG C 2 453 ? 143.353 139.715 175.514 1.00 42.45  ? 453 ARG C NH1 1 
ATOM   8023  N NH2 . ARG C 2 453 ? 141.371 138.627 175.154 1.00 43.04  ? 453 ARG C NH2 1 
ATOM   8024  N N   . ILE C 2 454 ? 148.549 138.253 169.287 1.00 41.38  ? 454 ILE C N   1 
ATOM   8025  C CA  . ILE C 2 454 ? 149.783 138.816 168.745 1.00 35.87  ? 454 ILE C CA  1 
ATOM   8026  C C   . ILE C 2 454 ? 150.334 137.970 167.606 1.00 37.48  ? 454 ILE C C   1 
ATOM   8027  O O   . ILE C 2 454 ? 150.690 138.496 166.552 1.00 32.68  ? 454 ILE C O   1 
ATOM   8028  C CB  . ILE C 2 454 ? 150.828 138.993 169.868 1.00 32.45  ? 454 ILE C CB  1 
ATOM   8029  C CG1 . ILE C 2 454 ? 150.306 139.957 170.933 1.00 38.78  ? 454 ILE C CG1 1 
ATOM   8030  C CG2 . ILE C 2 454 ? 152.148 139.479 169.298 1.00 31.03  ? 454 ILE C CG2 1 
ATOM   8031  C CD1 . ILE C 2 454 ? 151.136 139.982 172.195 1.00 44.43  ? 454 ILE C CD1 1 
ATOM   8032  N N   . VAL C 2 455 ? 150.403 136.651 167.801 1.00 41.42  ? 455 VAL C N   1 
ATOM   8033  C CA  . VAL C 2 455 ? 151.049 135.783 166.819 1.00 35.10  ? 455 VAL C CA  1 
ATOM   8034  C C   . VAL C 2 455 ? 150.283 135.794 165.504 1.00 31.60  ? 455 VAL C C   1 
ATOM   8035  O O   . VAL C 2 455 ? 150.883 135.889 164.427 1.00 31.71  ? 455 VAL C O   1 
ATOM   8036  C CB  . VAL C 2 455 ? 151.197 134.356 167.378 1.00 32.86  ? 455 VAL C CB  1 
ATOM   8037  C CG1 . VAL C 2 455 ? 151.694 133.414 166.297 1.00 35.51  ? 455 VAL C CG1 1 
ATOM   8038  C CG2 . VAL C 2 455 ? 152.155 134.351 168.556 1.00 33.16  ? 455 VAL C CG2 1 
ATOM   8039  N N   . PHE C 2 456 ? 148.957 135.688 165.562 1.00 28.55  ? 456 PHE C N   1 
ATOM   8040  C CA  . PHE C 2 456 ? 148.176 135.646 164.328 1.00 29.45  ? 456 PHE C CA  1 
ATOM   8041  C C   . PHE C 2 456 ? 148.341 136.922 163.511 1.00 31.39  ? 456 PHE C C   1 
ATOM   8042  O O   . PHE C 2 456 ? 148.662 136.821 162.314 1.00 33.28  ? 456 PHE C O   1 
ATOM   8043  C CB  . PHE C 2 456 ? 146.705 135.353 164.650 1.00 28.22  ? 456 PHE C CB  1 
ATOM   8044  C CG  . PHE C 2 456 ? 146.388 133.891 164.770 1.00 30.32  ? 456 PHE C CG  1 
ATOM   8045  C CD1 . PHE C 2 456 ? 146.572 133.229 165.971 1.00 27.18  ? 456 PHE C CD1 1 
ATOM   8046  C CD2 . PHE C 2 456 ? 145.908 133.180 163.685 1.00 26.49  ? 456 PHE C CD2 1 
ATOM   8047  C CE1 . PHE C 2 456 ? 146.283 131.886 166.088 1.00 27.06  ? 456 PHE C CE1 1 
ATOM   8048  C CE2 . PHE C 2 456 ? 145.616 131.836 163.797 1.00 22.96  ? 456 PHE C CE2 1 
ATOM   8049  C CZ  . PHE C 2 456 ? 145.804 131.189 165.000 1.00 21.39  ? 456 PHE C CZ  1 
ATOM   8050  N N   . PRO C 2 457 ? 148.128 138.131 164.056 1.00 30.13  ? 457 PRO C N   1 
ATOM   8051  C CA  . PRO C 2 457 ? 148.409 139.336 163.255 1.00 29.89  ? 457 PRO C CA  1 
ATOM   8052  C C   . PRO C 2 457 ? 149.858 139.438 162.813 1.00 33.06  ? 457 PRO C C   1 
ATOM   8053  O O   . PRO C 2 457 ? 150.135 139.896 161.698 1.00 36.21  ? 457 PRO C O   1 
ATOM   8054  C CB  . PRO C 2 457 ? 148.028 140.485 164.198 1.00 30.28  ? 457 PRO C CB  1 
ATOM   8055  C CG  . PRO C 2 457 ? 147.098 139.896 165.173 1.00 29.70  ? 457 PRO C CG  1 
ATOM   8056  C CD  . PRO C 2 457 ? 147.533 138.480 165.360 1.00 29.82  ? 457 PRO C CD  1 
ATOM   8057  N N   . PHE C 2 458 ? 150.795 139.025 163.670 1.00 31.89  ? 458 PHE C N   1 
ATOM   8058  C CA  . PHE C 2 458 ? 152.213 139.117 163.333 1.00 33.81  ? 458 PHE C CA  1 
ATOM   8059  C C   . PHE C 2 458 ? 152.586 138.143 162.223 1.00 32.68  ? 458 PHE C C   1 
ATOM   8060  O O   . PHE C 2 458 ? 153.306 138.509 161.287 1.00 30.53  ? 458 PHE C O   1 
ATOM   8061  C CB  . PHE C 2 458 ? 153.058 138.872 164.584 1.00 35.33  ? 458 PHE C CB  1 
ATOM   8062  C CG  . PHE C 2 458 ? 154.534 138.803 164.324 1.00 34.92  ? 458 PHE C CG  1 
ATOM   8063  C CD1 . PHE C 2 458 ? 155.285 139.961 164.226 1.00 29.94  ? 458 PHE C CD1 1 
ATOM   8064  C CD2 . PHE C 2 458 ? 155.175 137.582 164.200 1.00 41.16  ? 458 PHE C CD2 1 
ATOM   8065  C CE1 . PHE C 2 458 ? 156.645 139.903 163.994 1.00 39.93  ? 458 PHE C CE1 1 
ATOM   8066  C CE2 . PHE C 2 458 ? 156.534 137.517 163.967 1.00 45.98  ? 458 PHE C CE2 1 
ATOM   8067  C CZ  . PHE C 2 458 ? 157.270 138.680 163.864 1.00 46.68  ? 458 PHE C CZ  1 
ATOM   8068  N N   . THR C 2 459 ? 152.111 136.898 162.307 1.00 33.39  ? 459 THR C N   1 
ATOM   8069  C CA  . THR C 2 459 ? 152.457 135.919 161.282 1.00 29.82  ? 459 THR C CA  1 
ATOM   8070  C C   . THR C 2 459 ? 151.808 136.260 159.948 1.00 29.23  ? 459 THR C C   1 
ATOM   8071  O O   . THR C 2 459 ? 152.399 136.006 158.892 1.00 29.69  ? 459 THR C O   1 
ATOM   8072  C CB  . THR C 2 459 ? 152.042 134.518 161.730 1.00 28.73  ? 459 THR C CB  1 
ATOM   8073  O OG1 . THR C 2 459 ? 152.608 134.239 163.015 1.00 33.88  ? 459 THR C OG1 1 
ATOM   8074  C CG2 . THR C 2 459 ? 152.523 133.471 160.739 1.00 29.35  ? 459 THR C CG2 1 
ATOM   8075  N N   . PHE C 2 460 ? 150.604 136.834 159.969 1.00 28.50  ? 460 PHE C N   1 
ATOM   8076  C CA  . PHE C 2 460 ? 149.980 137.251 158.718 1.00 24.92  ? 460 PHE C CA  1 
ATOM   8077  C C   . PHE C 2 460 ? 150.744 138.407 158.087 1.00 28.52  ? 460 PHE C C   1 
ATOM   8078  O O   . PHE C 2 460 ? 150.895 138.462 156.861 1.00 30.94  ? 460 PHE C O   1 
ATOM   8079  C CB  . PHE C 2 460 ? 148.520 137.633 158.956 1.00 20.47  ? 460 PHE C CB  1 
ATOM   8080  C CG  . PHE C 2 460 ? 147.747 137.883 157.693 1.00 19.82  ? 460 PHE C CG  1 
ATOM   8081  C CD1 . PHE C 2 460 ? 147.519 136.860 156.791 1.00 19.39  ? 460 PHE C CD1 1 
ATOM   8082  C CD2 . PHE C 2 460 ? 147.241 139.139 157.412 1.00 18.81  ? 460 PHE C CD2 1 
ATOM   8083  C CE1 . PHE C 2 460 ? 146.807 137.087 155.631 1.00 17.07  ? 460 PHE C CE1 1 
ATOM   8084  C CE2 . PHE C 2 460 ? 146.528 139.370 156.255 1.00 15.94  ? 460 PHE C CE2 1 
ATOM   8085  C CZ  . PHE C 2 460 ? 146.311 138.342 155.364 1.00 16.17  ? 460 PHE C CZ  1 
ATOM   8086  N N   . SER C 2 461 ? 151.226 139.343 158.908 1.00 25.05  ? 461 SER C N   1 
ATOM   8087  C CA  . SER C 2 461 ? 152.059 140.421 158.386 1.00 26.99  ? 461 SER C CA  1 
ATOM   8088  C C   . SER C 2 461 ? 153.356 139.878 157.801 1.00 31.03  ? 461 SER C C   1 
ATOM   8089  O O   . SER C 2 461 ? 153.808 140.333 156.744 1.00 30.93  ? 461 SER C O   1 
ATOM   8090  C CB  . SER C 2 461 ? 152.348 141.441 159.485 1.00 26.39  ? 461 SER C CB  1 
ATOM   8091  O OG  . SER C 2 461 ? 151.148 142.001 159.986 1.00 26.78  ? 461 SER C OG  1 
ATOM   8092  N N   . LEU C 2 462 ? 153.970 138.904 158.477 1.00 33.29  ? 462 LEU C N   1 
ATOM   8093  C CA  . LEU C 2 462 ? 155.176 138.283 157.940 1.00 36.23  ? 462 LEU C CA  1 
ATOM   8094  C C   . LEU C 2 462 ? 154.878 137.540 156.645 1.00 32.79  ? 462 LEU C C   1 
ATOM   8095  O O   . LEU C 2 462 ? 155.676 137.579 155.701 1.00 32.80  ? 462 LEU C O   1 
ATOM   8096  C CB  . LEU C 2 462 ? 155.788 137.341 158.975 1.00 37.29  ? 462 LEU C CB  1 
ATOM   8097  C CG  . LEU C 2 462 ? 157.155 136.762 158.619 1.00 36.18  ? 462 LEU C CG  1 
ATOM   8098  C CD1 . LEU C 2 462 ? 158.170 137.880 158.460 1.00 40.62  ? 462 LEU C CD1 1 
ATOM   8099  C CD2 . LEU C 2 462 ? 157.607 135.770 159.677 1.00 38.18  ? 462 LEU C CD2 1 
ATOM   8100  N N   . PHE C 2 463 ? 153.736 136.850 156.584 1.00 30.82  ? 463 PHE C N   1 
ATOM   8101  C CA  . PHE C 2 463 ? 153.354 136.163 155.356 1.00 25.12  ? 463 PHE C CA  1 
ATOM   8102  C C   . PHE C 2 463 ? 153.178 137.156 154.220 1.00 29.93  ? 463 PHE C C   1 
ATOM   8103  O O   . PHE C 2 463 ? 153.588 136.892 153.084 1.00 37.23  ? 463 PHE C O   1 
ATOM   8104  C CB  . PHE C 2 463 ? 152.075 135.353 155.564 1.00 22.28  ? 463 PHE C CB  1 
ATOM   8105  C CG  . PHE C 2 463 ? 151.383 134.974 154.282 1.00 23.42  ? 463 PHE C CG  1 
ATOM   8106  C CD1 . PHE C 2 463 ? 151.829 133.897 153.536 1.00 22.18  ? 463 PHE C CD1 1 
ATOM   8107  C CD2 . PHE C 2 463 ? 150.282 135.681 153.831 1.00 24.82  ? 463 PHE C CD2 1 
ATOM   8108  C CE1 . PHE C 2 463 ? 151.198 133.540 152.360 1.00 20.19  ? 463 PHE C CE1 1 
ATOM   8109  C CE2 . PHE C 2 463 ? 149.648 135.326 152.655 1.00 21.66  ? 463 PHE C CE2 1 
ATOM   8110  C CZ  . PHE C 2 463 ? 150.106 134.255 151.921 1.00 18.77  ? 463 PHE C CZ  1 
ATOM   8111  N N   . ASN C 2 464 ? 152.558 138.302 154.506 1.00 27.18  ? 464 ASN C N   1 
ATOM   8112  C CA  . ASN C 2 464 ? 152.410 139.333 153.487 1.00 28.93  ? 464 ASN C CA  1 
ATOM   8113  C C   . ASN C 2 464 ? 153.764 139.886 153.067 1.00 35.24  ? 464 ASN C C   1 
ATOM   8114  O O   . ASN C 2 464 ? 154.009 140.102 151.875 1.00 31.44  ? 464 ASN C O   1 
ATOM   8115  C CB  . ASN C 2 464 ? 151.511 140.453 154.004 1.00 24.64  ? 464 ASN C CB  1 
ATOM   8116  C CG  . ASN C 2 464 ? 150.043 140.112 153.904 1.00 22.40  ? 464 ASN C CG  1 
ATOM   8117  O OD1 . ASN C 2 464 ? 149.405 140.356 152.881 1.00 21.79  ? 464 ASN C OD1 1 
ATOM   8118  N ND2 . ASN C 2 464 ? 149.497 139.540 154.969 1.00 23.46  ? 464 ASN C ND2 1 
ATOM   8119  N N   . LEU C 2 465 ? 154.663 140.112 154.029 1.00 39.31  ? 465 LEU C N   1 
ATOM   8120  C CA  . LEU C 2 465 ? 155.979 140.640 153.687 1.00 37.38  ? 465 LEU C CA  1 
ATOM   8121  C C   . LEU C 2 465 ? 156.718 139.682 152.763 1.00 35.76  ? 465 LEU C C   1 
ATOM   8122  O O   . LEU C 2 465 ? 157.305 140.097 151.759 1.00 36.43  ? 465 LEU C O   1 
ATOM   8123  C CB  . LEU C 2 465 ? 156.792 140.905 154.954 1.00 38.45  ? 465 LEU C CB  1 
ATOM   8124  C CG  . LEU C 2 465 ? 158.062 141.730 154.748 1.00 41.22  ? 465 LEU C CG  1 
ATOM   8125  C CD1 . LEU C 2 465 ? 157.715 143.196 154.554 1.00 44.15  ? 465 LEU C CD1 1 
ATOM   8126  C CD2 . LEU C 2 465 ? 159.020 141.551 155.912 1.00 46.59  ? 465 LEU C CD2 1 
ATOM   8127  N N   . VAL C 2 466 ? 156.695 138.389 153.089 1.00 34.69  ? 466 VAL C N   1 
ATOM   8128  C CA  . VAL C 2 466 ? 157.345 137.404 152.232 1.00 34.81  ? 466 VAL C CA  1 
ATOM   8129  C C   . VAL C 2 466 ? 156.621 137.316 150.896 1.00 39.22  ? 466 VAL C C   1 
ATOM   8130  O O   . VAL C 2 466 ? 157.244 137.120 149.846 1.00 41.37  ? 466 VAL C O   1 
ATOM   8131  C CB  . VAL C 2 466 ? 157.404 136.039 152.942 1.00 33.81  ? 466 VAL C CB  1 
ATOM   8132  C CG1 . VAL C 2 466 ? 157.939 134.968 152.006 1.00 36.79  ? 466 VAL C CG1 1 
ATOM   8133  C CG2 . VAL C 2 466 ? 158.262 136.132 154.191 1.00 37.46  ? 466 VAL C CG2 1 
ATOM   8134  N N   . TYR C 2 467 ? 155.295 137.464 150.912 1.00 36.00  ? 467 TYR C N   1 
ATOM   8135  C CA  . TYR C 2 467 ? 154.519 137.343 149.684 1.00 30.23  ? 467 TYR C CA  1 
ATOM   8136  C C   . TYR C 2 467 ? 154.826 138.486 148.726 1.00 35.13  ? 467 TYR C C   1 
ATOM   8137  O O   . TYR C 2 467 ? 155.125 138.258 147.549 1.00 38.91  ? 467 TYR C O   1 
ATOM   8138  C CB  . TYR C 2 467 ? 153.026 137.300 150.014 1.00 25.17  ? 467 TYR C CB  1 
ATOM   8139  C CG  . TYR C 2 467 ? 152.120 137.186 148.810 1.00 26.52  ? 467 TYR C CG  1 
ATOM   8140  C CD1 . TYR C 2 467 ? 151.779 135.948 148.289 1.00 23.97  ? 467 TYR C CD1 1 
ATOM   8141  C CD2 . TYR C 2 467 ? 151.589 138.317 148.207 1.00 28.13  ? 467 TYR C CD2 1 
ATOM   8142  C CE1 . TYR C 2 467 ? 150.949 135.841 147.195 1.00 20.76  ? 467 TYR C CE1 1 
ATOM   8143  C CE2 . TYR C 2 467 ? 150.759 138.218 147.115 1.00 22.64  ? 467 TYR C CE2 1 
ATOM   8144  C CZ  . TYR C 2 467 ? 150.441 136.979 146.612 1.00 20.29  ? 467 TYR C CZ  1 
ATOM   8145  O OH  . TYR C 2 467 ? 149.612 136.880 145.521 1.00 25.38  ? 467 TYR C OH  1 
ATOM   8146  N N   . TRP C 2 468 ? 154.757 139.727 149.213 1.00 34.90  ? 468 TRP C N   1 
ATOM   8147  C CA  . TRP C 2 468 ? 154.871 140.866 148.309 1.00 38.24  ? 468 TRP C CA  1 
ATOM   8148  C C   . TRP C 2 468 ? 156.303 141.068 147.828 1.00 43.95  ? 468 TRP C C   1 
ATOM   8149  O O   . TRP C 2 468 ? 156.512 141.453 146.674 1.00 49.31  ? 468 TRP C O   1 
ATOM   8150  C CB  . TRP C 2 468 ? 154.333 142.134 148.974 1.00 35.10  ? 468 TRP C CB  1 
ATOM   8151  C CG  . TRP C 2 468 ? 152.855 142.072 149.267 1.00 36.18  ? 468 TRP C CG  1 
ATOM   8152  C CD1 . TRP C 2 468 ? 152.268 141.919 150.488 1.00 36.89  ? 468 TRP C CD1 1 
ATOM   8153  C CD2 . TRP C 2 468 ? 151.784 142.130 148.314 1.00 31.71  ? 468 TRP C CD2 1 
ATOM   8154  N NE1 . TRP C 2 468 ? 150.901 141.892 150.358 1.00 30.82  ? 468 TRP C NE1 1 
ATOM   8155  C CE2 . TRP C 2 468 ? 150.579 142.019 149.034 1.00 27.90  ? 468 TRP C CE2 1 
ATOM   8156  C CE3 . TRP C 2 468 ? 151.728 142.271 146.925 1.00 29.80  ? 468 TRP C CE3 1 
ATOM   8157  C CZ2 . TRP C 2 468 ? 149.333 142.045 148.412 1.00 23.04  ? 468 TRP C CZ2 1 
ATOM   8158  C CZ3 . TRP C 2 468 ? 150.488 142.297 146.311 1.00 27.17  ? 468 TRP C CZ3 1 
ATOM   8159  C CH2 . TRP C 2 468 ? 149.310 142.184 147.054 1.00 24.45  ? 468 TRP C CH2 1 
ATOM   8160  N N   . LEU C 2 469 ? 157.300 140.790 148.672 1.00 43.34  ? 469 LEU C N   1 
ATOM   8161  C CA  . LEU C 2 469 ? 158.683 140.839 148.205 1.00 40.87  ? 469 LEU C CA  1 
ATOM   8162  C C   . LEU C 2 469 ? 158.934 139.797 147.123 1.00 39.13  ? 469 LEU C C   1 
ATOM   8163  O O   . LEU C 2 469 ? 159.600 140.081 146.120 1.00 47.92  ? 469 LEU C O   1 
ATOM   8164  C CB  . LEU C 2 469 ? 159.653 140.651 149.371 1.00 42.56  ? 469 LEU C CB  1 
ATOM   8165  C CG  . LEU C 2 469 ? 159.640 141.746 150.438 1.00 50.36  ? 469 LEU C CG  1 
ATOM   8166  C CD1 . LEU C 2 469 ? 160.693 141.473 151.500 1.00 53.80  ? 469 LEU C CD1 1 
ATOM   8167  C CD2 . LEU C 2 469 ? 159.855 143.111 149.803 1.00 41.85  ? 469 LEU C CD2 1 
ATOM   8168  N N   . TYR C 2 470 ? 158.413 138.586 147.307 1.00 35.94  ? 470 TYR C N   1 
ATOM   8169  C CA  . TYR C 2 470 ? 158.639 137.513 146.349 1.00 40.72  ? 470 TYR C CA  1 
ATOM   8170  C C   . TYR C 2 470 ? 157.853 137.714 145.058 1.00 40.64  ? 470 TYR C C   1 
ATOM   8171  O O   . TYR C 2 470 ? 158.129 137.024 144.072 1.00 42.21  ? 470 TYR C O   1 
ATOM   8172  C CB  . TYR C 2 470 ? 158.297 136.167 146.999 1.00 44.83  ? 470 TYR C CB  1 
ATOM   8173  C CG  . TYR C 2 470 ? 158.407 134.961 146.091 1.00 45.28  ? 470 TYR C CG  1 
ATOM   8174  C CD1 . TYR C 2 470 ? 159.619 134.308 145.920 1.00 44.73  ? 470 TYR C CD1 1 
ATOM   8175  C CD2 . TYR C 2 470 ? 157.294 134.455 145.434 1.00 44.94  ? 470 TYR C CD2 1 
ATOM   8176  C CE1 . TYR C 2 470 ? 159.726 133.201 145.100 1.00 54.26  ? 470 TYR C CE1 1 
ATOM   8177  C CE2 . TYR C 2 470 ? 157.391 133.350 144.611 1.00 49.43  ? 470 TYR C CE2 1 
ATOM   8178  C CZ  . TYR C 2 470 ? 158.608 132.726 144.450 1.00 63.12  ? 470 TYR C CZ  1 
ATOM   8179  O OH  . TYR C 2 470 ? 158.707 131.624 143.633 1.00 82.63  ? 470 TYR C OH  1 
ATOM   8180  N N   . TYR C 2 471 ? 156.916 138.661 145.022 1.00 38.17  ? 471 TYR C N   1 
ATOM   8181  C CA  . TYR C 2 471 ? 156.103 138.891 143.835 1.00 37.78  ? 471 TYR C CA  1 
ATOM   8182  C C   . TYR C 2 471 ? 156.156 140.317 143.304 1.00 43.24  ? 471 TYR C C   1 
ATOM   8183  O O   . TYR C 2 471 ? 155.928 140.514 142.109 1.00 45.35  ? 471 TYR C O   1 
ATOM   8184  C CB  . TYR C 2 471 ? 154.636 138.518 144.102 1.00 35.88  ? 471 TYR C CB  1 
ATOM   8185  C CG  . TYR C 2 471 ? 154.377 137.028 144.122 1.00 38.05  ? 471 TYR C CG  1 
ATOM   8186  C CD1 . TYR C 2 471 ? 154.460 136.276 142.958 1.00 40.48  ? 471 TYR C CD1 1 
ATOM   8187  C CD2 . TYR C 2 471 ? 154.030 136.376 145.297 1.00 32.82  ? 471 TYR C CD2 1 
ATOM   8188  C CE1 . TYR C 2 471 ? 154.222 134.916 142.967 1.00 35.02  ? 471 TYR C CE1 1 
ATOM   8189  C CE2 . TYR C 2 471 ? 153.787 135.016 145.314 1.00 29.55  ? 471 TYR C CE2 1 
ATOM   8190  C CZ  . TYR C 2 471 ? 153.883 134.292 144.146 1.00 29.53  ? 471 TYR C CZ  1 
ATOM   8191  O OH  . TYR C 2 471 ? 153.644 132.938 144.155 1.00 26.23  ? 471 TYR C OH  1 
ATOM   8192  N N   . VAL C 2 472 ? 156.443 141.311 144.139 1.00 44.80  ? 472 VAL C N   1 
ATOM   8193  C CA  . VAL C 2 472 ? 156.577 142.681 143.647 1.00 45.95  ? 472 VAL C CA  1 
ATOM   8194  C C   . VAL C 2 472 ? 158.033 142.954 143.295 1.00 45.53  ? 472 VAL C C   1 
ATOM   8195  O O   . VAL C 2 472 ? 158.859 142.042 143.279 1.00 43.87  ? 472 VAL C O   1 
ATOM   8196  C CB  . VAL C 2 472 ? 156.064 143.717 144.661 1.00 48.68  ? 472 VAL C CB  1 
ATOM   8197  C CG1 . VAL C 2 472 ? 156.210 145.121 144.099 1.00 50.15  ? 472 VAL C CG1 1 
ATOM   8198  C CG2 . VAL C 2 472 ? 154.618 143.438 145.024 1.00 43.91  ? 472 VAL C CG2 1 
ATOM   8199  N N   . THR D 1 47  ? 164.772 135.690 82.718  1.00 97.54  ? 12  THR D N   1 
ATOM   8200  C CA  . THR D 1 47  ? 163.610 135.210 83.454  1.00 98.37  ? 12  THR D CA  1 
ATOM   8201  C C   . THR D 1 47  ? 162.662 134.447 82.537  1.00 97.57  ? 12  THR D C   1 
ATOM   8202  O O   . THR D 1 47  ? 161.724 133.798 82.998  1.00 94.74  ? 12  THR D O   1 
ATOM   8203  C CB  . THR D 1 47  ? 162.847 136.371 84.113  1.00 98.87  ? 12  THR D CB  1 
ATOM   8204  O OG1 . THR D 1 47  ? 162.315 137.231 83.098  1.00 97.80  ? 12  THR D OG1 1 
ATOM   8205  C CG2 . THR D 1 47  ? 163.774 137.175 85.012  1.00 90.81  ? 12  THR D CG2 1 
ATOM   8206  N N   . THR D 1 48  ? 162.917 134.540 81.231  1.00 101.22 ? 13  THR D N   1 
ATOM   8207  C CA  . THR D 1 48  ? 162.066 133.867 80.255  1.00 100.17 ? 13  THR D CA  1 
ATOM   8208  C C   . THR D 1 48  ? 162.106 132.355 80.431  1.00 97.24  ? 13  THR D C   1 
ATOM   8209  O O   . THR D 1 48  ? 161.069 131.685 80.355  1.00 94.80  ? 13  THR D O   1 
ATOM   8210  C CB  . THR D 1 48  ? 162.489 134.251 78.837  1.00 101.67 ? 13  THR D CB  1 
ATOM   8211  O OG1 . THR D 1 48  ? 163.865 133.902 78.638  1.00 104.93 ? 13  THR D OG1 1 
ATOM   8212  C CG2 . THR D 1 48  ? 162.315 135.746 78.616  1.00 93.52  ? 13  THR D CG2 1 
ATOM   8213  N N   . VAL D 1 49  ? 163.299 131.800 80.657  1.00 99.70  ? 14  VAL D N   1 
ATOM   8214  C CA  . VAL D 1 49  ? 163.449 130.354 80.803  1.00 100.65 ? 14  VAL D CA  1 
ATOM   8215  C C   . VAL D 1 49  ? 162.610 129.834 81.964  1.00 95.96  ? 14  VAL D C   1 
ATOM   8216  O O   . VAL D 1 49  ? 161.947 128.796 81.852  1.00 92.97  ? 14  VAL D O   1 
ATOM   8217  C CB  . VAL D 1 49  ? 164.935 129.989 80.971  1.00 97.91  ? 14  VAL D CB  1 
ATOM   8218  C CG1 . VAL D 1 49  ? 165.095 128.493 81.200  1.00 92.15  ? 14  VAL D CG1 1 
ATOM   8219  C CG2 . VAL D 1 49  ? 165.730 130.438 79.756  1.00 92.93  ? 14  VAL D CG2 1 
ATOM   8220  N N   . PHE D 1 50  ? 162.625 130.543 83.095  1.00 94.77  ? 15  PHE D N   1 
ATOM   8221  C CA  . PHE D 1 50  ? 161.801 130.136 84.229  1.00 95.74  ? 15  PHE D CA  1 
ATOM   8222  C C   . PHE D 1 50  ? 160.317 130.192 83.883  1.00 98.13  ? 15  PHE D C   1 
ATOM   8223  O O   . PHE D 1 50  ? 159.551 129.296 84.256  1.00 96.48  ? 15  PHE D O   1 
ATOM   8224  C CB  . PHE D 1 50  ? 162.103 131.029 85.432  1.00 93.25  ? 15  PHE D CB  1 
ATOM   8225  C CG  . PHE D 1 50  ? 161.591 130.490 86.738  1.00 99.81  ? 15  PHE D CG  1 
ATOM   8226  C CD1 . PHE D 1 50  ? 160.272 130.673 87.113  1.00 98.13  ? 15  PHE D CD1 1 
ATOM   8227  C CD2 . PHE D 1 50  ? 162.441 129.828 87.607  1.00 100.52 ? 15  PHE D CD2 1 
ATOM   8228  C CE1 . PHE D 1 50  ? 159.804 130.187 88.319  1.00 95.50  ? 15  PHE D CE1 1 
ATOM   8229  C CE2 . PHE D 1 50  ? 161.982 129.345 88.815  1.00 95.85  ? 15  PHE D CE2 1 
ATOM   8230  C CZ  . PHE D 1 50  ? 160.661 129.522 89.171  1.00 90.86  ? 15  PHE D CZ  1 
ATOM   8231  N N   . THR D 1 51  ? 159.893 131.241 83.176  1.00 99.35  ? 16  THR D N   1 
ATOM   8232  C CA  . THR D 1 51  ? 158.481 131.385 82.832  1.00 94.84  ? 16  THR D CA  1 
ATOM   8233  C C   . THR D 1 51  ? 158.017 130.271 81.902  1.00 89.98  ? 16  THR D C   1 
ATOM   8234  O O   . THR D 1 51  ? 156.921 129.725 82.074  1.00 87.21  ? 16  THR D O   1 
ATOM   8235  C CB  . THR D 1 51  ? 158.233 132.753 82.196  1.00 96.63  ? 16  THR D CB  1 
ATOM   8236  O OG1 . THR D 1 51  ? 158.609 133.784 83.117  1.00 98.22  ? 16  THR D OG1 1 
ATOM   8237  C CG2 . THR D 1 51  ? 156.763 132.916 81.833  1.00 85.62  ? 16  THR D CG2 1 
ATOM   8238  N N   . ARG D 1 52  ? 158.835 129.927 80.906  1.00 91.51  ? 17  ARG D N   1 
ATOM   8239  C CA  . ARG D 1 52  ? 158.439 128.916 79.931  1.00 90.70  ? 17  ARG D CA  1 
ATOM   8240  C C   . ARG D 1 52  ? 158.220 127.556 80.583  1.00 88.94  ? 17  ARG D C   1 
ATOM   8241  O O   . ARG D 1 52  ? 157.261 126.850 80.250  1.00 87.49  ? 17  ARG D O   1 
ATOM   8242  C CB  . ARG D 1 52  ? 159.490 128.820 78.826  1.00 98.31  ? 17  ARG D CB  1 
ATOM   8243  C CG  . ARG D 1 52  ? 159.608 130.077 77.977  1.00 101.95 ? 17  ARG D CG  1 
ATOM   8244  C CD  . ARG D 1 52  ? 160.220 129.778 76.618  1.00 106.29 ? 17  ARG D CD  1 
ATOM   8245  N NE  . ARG D 1 52  ? 161.431 128.974 76.729  1.00 109.91 ? 17  ARG D NE  1 
ATOM   8246  C CZ  . ARG D 1 52  ? 162.642 129.470 76.944  1.00 109.94 ? 17  ARG D CZ  1 
ATOM   8247  N NH1 . ARG D 1 52  ? 162.841 130.770 77.090  1.00 107.99 ? 17  ARG D NH1 1 
ATOM   8248  N NH2 . ARG D 1 52  ? 163.679 128.640 77.020  1.00 108.02 ? 17  ARG D NH2 1 
ATOM   8249  N N   . ILE D 1 53  ? 159.106 127.164 81.503  1.00 86.90  ? 18  ILE D N   1 
ATOM   8250  C CA  . ILE D 1 53  ? 159.005 125.842 82.120  1.00 87.36  ? 18  ILE D CA  1 
ATOM   8251  C C   . ILE D 1 53  ? 157.670 125.677 82.839  1.00 94.31  ? 18  ILE D C   1 
ATOM   8252  O O   . ILE D 1 53  ? 157.052 124.606 82.792  1.00 93.65  ? 18  ILE D O   1 
ATOM   8253  C CB  . ILE D 1 53  ? 160.194 125.609 83.070  1.00 84.96  ? 18  ILE D CB  1 
ATOM   8254  C CG1 . ILE D 1 53  ? 161.508 125.631 82.290  1.00 88.81  ? 18  ILE D CG1 1 
ATOM   8255  C CG2 . ILE D 1 53  ? 160.041 124.291 83.811  1.00 83.61  ? 18  ILE D CG2 1 
ATOM   8256  C CD1 . ILE D 1 53  ? 162.737 125.674 83.169  1.00 92.19  ? 18  ILE D CD1 1 
ATOM   8257  N N   . LEU D 1 54  ? 157.205 126.731 83.516  1.00 98.09  ? 19  LEU D N   1 
ATOM   8258  C CA  . LEU D 1 54  ? 155.952 126.645 84.262  1.00 91.58  ? 19  LEU D CA  1 
ATOM   8259  C C   . LEU D 1 54  ? 154.778 126.334 83.341  1.00 92.69  ? 19  LEU D C   1 
ATOM   8260  O O   . LEU D 1 54  ? 153.937 125.482 83.649  1.00 87.01  ? 19  LEU D O   1 
ATOM   8261  C CB  . LEU D 1 54  ? 155.712 127.945 85.028  1.00 85.49  ? 19  LEU D CB  1 
ATOM   8262  C CG  . LEU D 1 54  ? 156.788 128.309 86.049  1.00 86.56  ? 19  LEU D CG  1 
ATOM   8263  C CD1 . LEU D 1 54  ? 156.472 129.639 86.715  1.00 89.07  ? 19  LEU D CD1 1 
ATOM   8264  C CD2 . LEU D 1 54  ? 156.936 127.206 87.085  1.00 83.40  ? 19  LEU D CD2 1 
ATOM   8265  N N   . ASP D 1 55  ? 154.705 127.026 82.201  1.00 93.49  ? 20  ASP D N   1 
ATOM   8266  C CA  . ASP D 1 55  ? 153.610 126.808 81.261  1.00 89.45  ? 20  ASP D CA  1 
ATOM   8267  C C   . ASP D 1 55  ? 153.647 125.399 80.681  1.00 91.14  ? 20  ASP D C   1 
ATOM   8268  O O   . ASP D 1 55  ? 152.601 124.758 80.522  1.00 90.46  ? 20  ASP D O   1 
ATOM   8269  C CB  . ASP D 1 55  ? 153.663 127.853 80.148  1.00 88.83  ? 20  ASP D CB  1 
ATOM   8270  C CG  . ASP D 1 55  ? 153.793 129.265 80.683  1.00 87.86  ? 20  ASP D CG  1 
ATOM   8271  O OD1 . ASP D 1 55  ? 154.078 129.421 81.889  1.00 89.51  ? 20  ASP D OD1 1 
ATOM   8272  O OD2 . ASP D 1 55  ? 153.610 130.220 79.900  1.00 88.38  ? 20  ASP D OD2 1 
ATOM   8273  N N   . ARG D 1 56  ? 154.843 124.903 80.358  1.00 90.48  ? 21  ARG D N   1 
ATOM   8274  C CA  . ARG D 1 56  ? 154.966 123.598 79.718  1.00 92.89  ? 21  ARG D CA  1 
ATOM   8275  C C   . ARG D 1 56  ? 154.577 122.466 80.664  1.00 94.82  ? 21  ARG D C   1 
ATOM   8276  O O   . ARG D 1 56  ? 154.124 121.410 80.208  1.00 98.48  ? 21  ARG D O   1 
ATOM   8277  C CB  . ARG D 1 56  ? 156.392 123.419 79.188  1.00 90.97  ? 21  ARG D CB  1 
ATOM   8278  C CG  . ARG D 1 56  ? 156.688 122.059 78.575  1.00 92.86  ? 21  ARG D CG  1 
ATOM   8279  C CD  . ARG D 1 56  ? 158.054 122.042 77.897  1.00 96.87  ? 21  ARG D CD  1 
ATOM   8280  N NE  . ARG D 1 56  ? 159.132 122.442 78.793  1.00 102.62 ? 21  ARG D NE  1 
ATOM   8281  C CZ  . ARG D 1 56  ? 159.837 121.603 79.538  1.00 103.23 ? 21  ARG D CZ  1 
ATOM   8282  N NH1 . ARG D 1 56  ? 159.601 120.302 79.526  1.00 99.49  ? 21  ARG D NH1 1 
ATOM   8283  N NH2 . ARG D 1 56  ? 160.803 122.082 80.317  1.00 95.30  ? 21  ARG D NH2 1 
ATOM   8284  N N   . LEU D 1 57  ? 154.739 122.668 81.975  1.00 89.55  ? 22  LEU D N   1 
ATOM   8285  C CA  . LEU D 1 57  ? 154.511 121.594 82.939  1.00 87.28  ? 22  LEU D CA  1 
ATOM   8286  C C   . LEU D 1 57  ? 153.072 121.090 82.892  1.00 88.69  ? 22  LEU D C   1 
ATOM   8287  O O   . LEU D 1 57  ? 152.828 119.883 82.792  1.00 84.10  ? 22  LEU D O   1 
ATOM   8288  C CB  . LEU D 1 57  ? 154.859 122.071 84.349  1.00 77.69  ? 22  LEU D CB  1 
ATOM   8289  C CG  . LEU D 1 57  ? 156.318 121.971 84.789  1.00 76.24  ? 22  LEU D CG  1 
ATOM   8290  C CD1 . LEU D 1 57  ? 156.480 122.522 86.194  1.00 79.42  ? 22  LEU D CD1 1 
ATOM   8291  C CD2 . LEU D 1 57  ? 156.799 120.533 84.718  1.00 70.14  ? 22  LEU D CD2 1 
ATOM   8292  N N   . LEU D 1 58  ? 152.104 122.002 82.956  1.00 87.84  ? 23  LEU D N   1 
ATOM   8293  C CA  . LEU D 1 58  ? 150.692 121.642 83.018  1.00 82.30  ? 23  LEU D CA  1 
ATOM   8294  C C   . LEU D 1 58  ? 150.071 121.386 81.652  1.00 86.03  ? 23  LEU D C   1 
ATOM   8295  O O   . LEU D 1 58  ? 148.845 121.485 81.518  1.00 83.04  ? 23  LEU D O   1 
ATOM   8296  C CB  . LEU D 1 58  ? 149.902 122.731 83.746  1.00 77.91  ? 23  LEU D CB  1 
ATOM   8297  C CG  . LEU D 1 58  ? 150.374 123.066 85.157  1.00 78.25  ? 23  LEU D CG  1 
ATOM   8298  C CD1 . LEU D 1 58  ? 149.446 124.085 85.795  1.00 75.21  ? 23  LEU D CD1 1 
ATOM   8299  C CD2 . LEU D 1 58  ? 150.453 121.805 85.991  1.00 71.85  ? 23  LEU D CD2 1 
ATOM   8300  N N   . ASP D 1 59  ? 150.871 121.065 80.640  1.00 91.00  ? 24  ASP D N   1 
ATOM   8301  C CA  . ASP D 1 59  ? 150.349 120.785 79.308  1.00 94.22  ? 24  ASP D CA  1 
ATOM   8302  C C   . ASP D 1 59  ? 149.820 119.355 79.290  1.00 94.70  ? 24  ASP D C   1 
ATOM   8303  O O   . ASP D 1 59  ? 150.599 118.397 79.260  1.00 96.24  ? 24  ASP D O   1 
ATOM   8304  C CB  . ASP D 1 59  ? 151.435 120.989 78.255  1.00 94.18  ? 24  ASP D CB  1 
ATOM   8305  C CG  . ASP D 1 59  ? 150.940 120.732 76.842  1.00 101.36 ? 24  ASP D CG  1 
ATOM   8306  O OD1 . ASP D 1 59  ? 149.710 120.650 76.639  1.00 102.29 ? 24  ASP D OD1 1 
ATOM   8307  O OD2 . ASP D 1 59  ? 151.786 120.611 75.930  1.00 105.14 ? 24  ASP D OD2 1 
ATOM   8308  N N   . GLY D 1 60  ? 148.496 119.210 79.306  1.00 87.90  ? 25  GLY D N   1 
ATOM   8309  C CA  . GLY D 1 60  ? 147.868 117.906 79.328  1.00 83.54  ? 25  GLY D CA  1 
ATOM   8310  C C   . GLY D 1 60  ? 147.791 117.243 80.685  1.00 78.39  ? 25  GLY D C   1 
ATOM   8311  O O   . GLY D 1 60  ? 147.289 116.115 80.775  1.00 77.81  ? 25  GLY D O   1 
ATOM   8312  N N   . TYR D 1 61  ? 148.275 117.894 81.740  1.00 75.81  ? 26  TYR D N   1 
ATOM   8313  C CA  . TYR D 1 61  ? 148.227 117.312 83.075  1.00 70.91  ? 26  TYR D CA  1 
ATOM   8314  C C   . TYR D 1 61  ? 146.782 117.199 83.548  1.00 66.91  ? 26  TYR D C   1 
ATOM   8315  O O   . TYR D 1 61  ? 146.018 118.166 83.476  1.00 70.61  ? 26  TYR D O   1 
ATOM   8316  C CB  . TYR D 1 61  ? 149.040 118.174 84.039  1.00 69.79  ? 26  TYR D CB  1 
ATOM   8317  C CG  . TYR D 1 61  ? 149.202 117.605 85.427  1.00 61.73  ? 26  TYR D CG  1 
ATOM   8318  C CD1 . TYR D 1 61  ? 148.247 117.828 86.408  1.00 57.74  ? 26  TYR D CD1 1 
ATOM   8319  C CD2 . TYR D 1 61  ? 150.322 116.860 85.763  1.00 60.76  ? 26  TYR D CD2 1 
ATOM   8320  C CE1 . TYR D 1 61  ? 148.397 117.314 87.677  1.00 53.77  ? 26  TYR D CE1 1 
ATOM   8321  C CE2 . TYR D 1 61  ? 150.480 116.343 87.030  1.00 58.35  ? 26  TYR D CE2 1 
ATOM   8322  C CZ  . TYR D 1 61  ? 149.515 116.575 87.985  1.00 54.05  ? 26  TYR D CZ  1 
ATOM   8323  O OH  . TYR D 1 61  ? 149.666 116.062 89.252  1.00 52.15  ? 26  TYR D OH  1 
ATOM   8324  N N   . ASP D 1 62  ? 146.408 116.016 84.033  1.00 60.81  ? 27  ASP D N   1 
ATOM   8325  C CA  . ASP D 1 62  ? 145.068 115.758 84.555  1.00 58.08  ? 27  ASP D CA  1 
ATOM   8326  C C   . ASP D 1 62  ? 145.147 115.598 86.069  1.00 55.84  ? 27  ASP D C   1 
ATOM   8327  O O   . ASP D 1 62  ? 145.628 114.574 86.565  1.00 53.93  ? 27  ASP D O   1 
ATOM   8328  C CB  . ASP D 1 62  ? 144.464 114.515 83.905  1.00 56.60  ? 27  ASP D CB  1 
ATOM   8329  C CG  . ASP D 1 62  ? 142.952 114.483 84.003  1.00 57.95  ? 27  ASP D CG  1 
ATOM   8330  O OD1 . ASP D 1 62  ? 142.366 115.469 84.496  1.00 53.91  ? 27  ASP D OD1 1 
ATOM   8331  O OD2 . ASP D 1 62  ? 142.350 113.472 83.586  1.00 62.72  ? 27  ASP D OD2 1 
ATOM   8332  N N   . ASN D 1 63  ? 144.671 116.604 86.801  1.00 57.19  ? 28  ASN D N   1 
ATOM   8333  C CA  . ASN D 1 63  ? 144.748 116.577 88.255  1.00 53.18  ? 28  ASN D CA  1 
ATOM   8334  C C   . ASN D 1 63  ? 143.665 115.722 88.902  1.00 50.85  ? 28  ASN D C   1 
ATOM   8335  O O   . ASN D 1 63  ? 143.684 115.555 90.126  1.00 52.08  ? 28  ASN D O   1 
ATOM   8336  C CB  . ASN D 1 63  ? 144.669 118.002 88.808  1.00 51.87  ? 28  ASN D CB  1 
ATOM   8337  C CG  . ASN D 1 63  ? 143.359 118.687 88.472  1.00 51.21  ? 28  ASN D CG  1 
ATOM   8338  O OD1 . ASN D 1 63  ? 142.610 118.232 87.608  1.00 53.53  ? 28  ASN D OD1 1 
ATOM   8339  N ND2 . ASN D 1 63  ? 143.075 119.786 89.158  1.00 51.75  ? 28  ASN D ND2 1 
ATOM   8340  N N   . ARG D 1 64  ? 142.725 115.185 88.123  1.00 49.48  ? 29  ARG D N   1 
ATOM   8341  C CA  . ARG D 1 64  ? 141.729 114.263 88.657  1.00 48.30  ? 29  ARG D CA  1 
ATOM   8342  C C   . ARG D 1 64  ? 142.262 112.850 88.848  1.00 48.89  ? 29  ARG D C   1 
ATOM   8343  O O   . ARG D 1 64  ? 141.627 112.053 89.546  1.00 44.26  ? 29  ARG D O   1 
ATOM   8344  C CB  . ARG D 1 64  ? 140.505 114.229 87.741  1.00 44.81  ? 29  ARG D CB  1 
ATOM   8345  C CG  . ARG D 1 64  ? 139.737 115.534 87.706  1.00 43.53  ? 29  ARG D CG  1 
ATOM   8346  C CD  . ARG D 1 64  ? 138.616 115.491 86.690  1.00 40.45  ? 29  ARG D CD  1 
ATOM   8347  N NE  . ARG D 1 64  ? 139.123 115.296 85.338  1.00 42.40  ? 29  ARG D NE  1 
ATOM   8348  C CZ  . ARG D 1 64  ? 138.393 115.428 84.240  1.00 47.04  ? 29  ARG D CZ  1 
ATOM   8349  N NH1 . ARG D 1 64  ? 137.117 115.770 84.296  1.00 37.37  ? 29  ARG D NH1 1 
ATOM   8350  N NH2 . ARG D 1 64  ? 138.958 115.214 83.056  1.00 57.94  ? 29  ARG D NH2 1 
ATOM   8351  N N   . LEU D 1 65  ? 143.405 112.527 88.255  1.00 51.06  ? 30  LEU D N   1 
ATOM   8352  C CA  . LEU D 1 65  ? 143.980 111.191 88.316  1.00 47.10  ? 30  LEU D CA  1 
ATOM   8353  C C   . LEU D 1 65  ? 145.241 111.208 89.166  1.00 47.96  ? 30  LEU D C   1 
ATOM   8354  O O   . LEU D 1 65  ? 146.120 112.052 88.964  1.00 47.99  ? 30  LEU D O   1 
ATOM   8355  C CB  . LEU D 1 65  ? 144.296 110.669 86.913  1.00 49.39  ? 30  LEU D CB  1 
ATOM   8356  C CG  . LEU D 1 65  ? 143.207 110.842 85.852  1.00 47.43  ? 30  LEU D CG  1 
ATOM   8357  C CD1 . LEU D 1 65  ? 143.628 110.180 84.553  1.00 46.09  ? 30  LEU D CD1 1 
ATOM   8358  C CD2 . LEU D 1 65  ? 141.877 110.287 86.334  1.00 45.60  ? 30  LEU D CD2 1 
ATOM   8359  N N   . ARG D 1 66  ? 145.326 110.275 90.108  1.00 47.11  ? 31  ARG D N   1 
ATOM   8360  C CA  . ARG D 1 66  ? 146.501 110.162 90.949  1.00 44.68  ? 31  ARG D CA  1 
ATOM   8361  C C   . ARG D 1 66  ? 147.679 109.646 90.126  1.00 51.32  ? 31  ARG D C   1 
ATOM   8362  O O   . ARG D 1 66  ? 147.489 109.026 89.077  1.00 57.75  ? 31  ARG D O   1 
ATOM   8363  C CB  . ARG D 1 66  ? 146.226 109.222 92.119  1.00 39.78  ? 31  ARG D CB  1 
ATOM   8364  C CG  . ARG D 1 66  ? 145.852 107.816 91.691  1.00 49.26  ? 31  ARG D CG  1 
ATOM   8365  C CD  . ARG D 1 66  ? 145.882 106.847 92.857  1.00 50.03  ? 31  ARG D CD  1 
ATOM   8366  N NE  . ARG D 1 66  ? 145.750 105.467 92.408  1.00 53.54  ? 31  ARG D NE  1 
ATOM   8367  C CZ  . ARG D 1 66  ? 146.768 104.691 92.064  1.00 56.22  ? 31  ARG D CZ  1 
ATOM   8368  N NH1 . ARG D 1 66  ? 148.016 105.123 92.123  1.00 57.16  ? 31  ARG D NH1 1 
ATOM   8369  N NH2 . ARG D 1 66  ? 146.527 103.449 91.654  1.00 53.53  ? 31  ARG D NH2 1 
ATOM   8370  N N   . PRO D 1 67  ? 148.908 109.913 90.567  1.00 48.30  ? 32  PRO D N   1 
ATOM   8371  C CA  . PRO D 1 67  ? 150.074 109.369 89.860  1.00 51.88  ? 32  PRO D CA  1 
ATOM   8372  C C   . PRO D 1 67  ? 150.032 107.850 89.798  1.00 57.34  ? 32  PRO D C   1 
ATOM   8373  O O   . PRO D 1 67  ? 149.684 107.177 90.770  1.00 55.18  ? 32  PRO D O   1 
ATOM   8374  C CB  . PRO D 1 67  ? 151.261 109.865 90.692  1.00 52.62  ? 32  PRO D CB  1 
ATOM   8375  C CG  . PRO D 1 67  ? 150.742 111.018 91.468  1.00 49.69  ? 32  PRO D CG  1 
ATOM   8376  C CD  . PRO D 1 67  ? 149.294 110.760 91.708  1.00 46.92  ? 32  PRO D CD  1 
ATOM   8377  N N   . GLY D 1 68  ? 150.399 107.314 88.637  1.00 65.88  ? 33  GLY D N   1 
ATOM   8378  C CA  . GLY D 1 68  ? 150.420 105.876 88.460  1.00 71.32  ? 33  GLY D CA  1 
ATOM   8379  C C   . GLY D 1 68  ? 149.067 105.207 88.534  1.00 67.82  ? 33  GLY D C   1 
ATOM   8380  O O   . GLY D 1 68  ? 148.990 104.024 88.882  1.00 70.63  ? 33  GLY D O   1 
ATOM   8381  N N   . LEU D 1 69  ? 147.993 105.938 88.235  1.00 63.17  ? 34  LEU D N   1 
ATOM   8382  C CA  . LEU D 1 69  ? 146.654 105.364 88.288  1.00 63.48  ? 34  LEU D CA  1 
ATOM   8383  C C   . LEU D 1 69  ? 146.570 104.150 87.370  1.00 67.65  ? 34  LEU D C   1 
ATOM   8384  O O   . LEU D 1 69  ? 146.937 104.216 86.194  1.00 61.11  ? 34  LEU D O   1 
ATOM   8385  C CB  . LEU D 1 69  ? 145.611 106.409 87.889  1.00 58.12  ? 34  LEU D CB  1 
ATOM   8386  C CG  . LEU D 1 69  ? 144.175 105.915 87.692  1.00 56.83  ? 34  LEU D CG  1 
ATOM   8387  C CD1 . LEU D 1 69  ? 143.691 105.143 88.912  1.00 58.70  ? 34  LEU D CD1 1 
ATOM   8388  C CD2 . LEU D 1 69  ? 143.243 107.073 87.393  1.00 53.89  ? 34  LEU D CD2 1 
ATOM   8389  N N   . GLY D 1 70  ? 146.084 103.039 87.918  1.00 71.37  ? 35  GLY D N   1 
ATOM   8390  C CA  . GLY D 1 70  ? 145.981 101.802 87.172  1.00 67.77  ? 35  GLY D CA  1 
ATOM   8391  C C   . GLY D 1 70  ? 147.304 101.156 86.839  1.00 73.63  ? 35  GLY D C   1 
ATOM   8392  O O   . GLY D 1 70  ? 147.329 100.177 86.089  1.00 77.19  ? 35  GLY D O   1 
ATOM   8393  N N   . GLU D 1 71  ? 148.406 101.675 87.374  1.00 73.57  ? 36  GLU D N   1 
ATOM   8394  C CA  . GLU D 1 71  ? 149.748 101.190 87.077  1.00 78.54  ? 36  GLU D CA  1 
ATOM   8395  C C   . GLU D 1 71  ? 150.523 100.781 88.318  1.00 78.40  ? 36  GLU D C   1 
ATOM   8396  O O   . GLU D 1 71  ? 151.221 99.765  88.298  1.00 79.85  ? 36  GLU D O   1 
ATOM   8397  C CB  . GLU D 1 71  ? 150.538 102.268 86.319  1.00 78.34  ? 36  GLU D CB  1 
ATOM   8398  C CG  . GLU D 1 71  ? 151.934 101.840 85.896  1.00 82.21  ? 36  GLU D CG  1 
ATOM   8399  C CD  . GLU D 1 71  ? 152.618 102.872 85.020  1.00 86.05  ? 36  GLU D CD  1 
ATOM   8400  O OE1 . GLU D 1 71  ? 151.974 103.888 84.684  1.00 88.32  ? 36  GLU D OE1 1 
ATOM   8401  O OE2 . GLU D 1 71  ? 153.797 102.666 84.666  1.00 87.38  ? 36  GLU D OE2 1 
ATOM   8402  N N   . ARG D 1 72  ? 150.412 101.543 89.401  1.00 78.14  ? 37  ARG D N   1 
ATOM   8403  C CA  . ARG D 1 72  ? 151.118 101.262 90.645  1.00 75.39  ? 37  ARG D CA  1 
ATOM   8404  C C   . ARG D 1 72  ? 150.359 101.941 91.780  1.00 67.58  ? 37  ARG D C   1 
ATOM   8405  O O   . ARG D 1 72  ? 149.268 102.486 91.581  1.00 67.48  ? 37  ARG D O   1 
ATOM   8406  C CB  . ARG D 1 72  ? 152.574 101.734 90.570  1.00 75.61  ? 37  ARG D CB  1 
ATOM   8407  C CG  . ARG D 1 72  ? 152.720 103.235 90.401  1.00 74.97  ? 37  ARG D CG  1 
ATOM   8408  C CD  . ARG D 1 72  ? 154.177 103.662 90.408  1.00 73.60  ? 37  ARG D CD  1 
ATOM   8409  N NE  . ARG D 1 72  ? 154.310 105.111 90.492  1.00 75.02  ? 37  ARG D NE  1 
ATOM   8410  C CZ  . ARG D 1 72  ? 154.228 105.933 89.455  1.00 74.34  ? 37  ARG D CZ  1 
ATOM   8411  N NH1 . ARG D 1 72  ? 154.005 105.482 88.231  1.00 73.87  ? 37  ARG D NH1 1 
ATOM   8412  N NH2 . ARG D 1 72  ? 154.367 107.241 89.651  1.00 69.74  ? 37  ARG D NH2 1 
ATOM   8413  N N   . VAL D 1 73  ? 150.936 101.906 92.977  1.00 56.33  ? 38  VAL D N   1 
ATOM   8414  C CA  . VAL D 1 73  ? 150.326 102.487 94.167  1.00 49.82  ? 38  VAL D CA  1 
ATOM   8415  C C   . VAL D 1 73  ? 151.098 103.752 94.507  1.00 51.44  ? 38  VAL D C   1 
ATOM   8416  O O   . VAL D 1 73  ? 152.323 103.714 94.674  1.00 54.06  ? 38  VAL D O   1 
ATOM   8417  C CB  . VAL D 1 73  ? 150.330 101.504 95.346  1.00 48.69  ? 38  VAL D CB  1 
ATOM   8418  C CG1 . VAL D 1 73  ? 149.657 102.127 96.549  1.00 46.52  ? 38  VAL D CG1 1 
ATOM   8419  C CG2 . VAL D 1 73  ? 149.637 100.208 94.957  1.00 54.12  ? 38  VAL D CG2 1 
ATOM   8420  N N   . THR D 1 74  ? 150.386 104.872 94.601  1.00 52.31  ? 39  THR D N   1 
ATOM   8421  C CA  . THR D 1 74  ? 151.012 106.129 94.987  1.00 51.57  ? 39  THR D CA  1 
ATOM   8422  C C   . THR D 1 74  ? 151.474 106.078 96.438  1.00 43.96  ? 39  THR D C   1 
ATOM   8423  O O   . THR D 1 74  ? 150.692 105.765 97.340  1.00 40.85  ? 39  THR D O   1 
ATOM   8424  C CB  . THR D 1 74  ? 150.040 107.290 94.786  1.00 46.79  ? 39  THR D CB  1 
ATOM   8425  O OG1 . THR D 1 74  ? 149.518 107.248 93.453  1.00 56.76  ? 39  THR D OG1 1 
ATOM   8426  C CG2 . THR D 1 74  ? 150.747 108.617 95.002  1.00 39.16  ? 39  THR D CG2 1 
ATOM   8427  N N   . GLU D 1 75  ? 152.745 106.396 96.660  1.00 45.90  ? 40  GLU D N   1 
ATOM   8428  C CA  . GLU D 1 75  ? 153.355 106.363 97.984  1.00 43.98  ? 40  GLU D CA  1 
ATOM   8429  C C   . GLU D 1 75  ? 153.603 107.799 98.424  1.00 41.02  ? 40  GLU D C   1 
ATOM   8430  O O   . GLU D 1 75  ? 154.464 108.486 97.864  1.00 40.40  ? 40  GLU D O   1 
ATOM   8431  C CB  . GLU D 1 75  ? 154.650 105.555 97.970  1.00 47.29  ? 40  GLU D CB  1 
ATOM   8432  C CG  . GLU D 1 75  ? 155.356 105.505 99.311  1.00 52.79  ? 40  GLU D CG  1 
ATOM   8433  C CD  . GLU D 1 75  ? 156.639 104.703 99.263  1.00 67.79  ? 40  GLU D CD  1 
ATOM   8434  O OE1 . GLU D 1 75  ? 156.778 103.858 98.353  1.00 69.63  ? 40  GLU D OE1 1 
ATOM   8435  O OE2 . GLU D 1 75  ? 157.510 104.919 100.132 1.00 70.50  ? 40  GLU D OE2 1 
ATOM   8436  N N   . VAL D 1 76  ? 152.857 108.248 99.428  1.00 37.87  ? 41  VAL D N   1 
ATOM   8437  C CA  . VAL D 1 76  ? 152.965 109.606 99.947  1.00 34.83  ? 41  VAL D CA  1 
ATOM   8438  C C   . VAL D 1 76  ? 153.743 109.561 101.254 1.00 33.38  ? 41  VAL D C   1 
ATOM   8439  O O   . VAL D 1 76  ? 153.372 108.833 102.182 1.00 33.44  ? 41  VAL D O   1 
ATOM   8440  C CB  . VAL D 1 76  ? 151.580 110.240 100.150 1.00 29.87  ? 41  VAL D CB  1 
ATOM   8441  C CG1 . VAL D 1 76  ? 151.717 111.645 100.706 1.00 26.80  ? 41  VAL D CG1 1 
ATOM   8442  C CG2 . VAL D 1 76  ? 150.806 110.250 98.844  1.00 28.10  ? 41  VAL D CG2 1 
ATOM   8443  N N   . LYS D 1 77  ? 154.819 110.338 101.330 1.00 31.89  ? 42  LYS D N   1 
ATOM   8444  C CA  . LYS D 1 77  ? 155.643 110.420 102.528 1.00 26.49  ? 42  LYS D CA  1 
ATOM   8445  C C   . LYS D 1 77  ? 155.290 111.687 103.293 1.00 26.50  ? 42  LYS D C   1 
ATOM   8446  O O   . LYS D 1 77  ? 155.348 112.789 102.738 1.00 30.74  ? 42  LYS D O   1 
ATOM   8447  C CB  . LYS D 1 77  ? 157.129 110.414 102.168 1.00 26.92  ? 42  LYS D CB  1 
ATOM   8448  C CG  . LYS D 1 77  ? 157.661 109.053 101.762 1.00 38.01  ? 42  LYS D CG  1 
ATOM   8449  C CD  . LYS D 1 77  ? 159.147 109.114 101.458 1.00 54.49  ? 42  LYS D CD  1 
ATOM   8450  C CE  . LYS D 1 77  ? 159.702 107.739 101.127 1.00 65.52  ? 42  LYS D CE  1 
ATOM   8451  N NZ  . LYS D 1 77  ? 159.564 106.791 102.265 1.00 56.06  ? 42  LYS D NZ  1 
ATOM   8452  N N   . THR D 1 78  ? 154.935 111.531 104.565 1.00 27.64  ? 43  THR D N   1 
ATOM   8453  C CA  . THR D 1 78  ? 154.420 112.627 105.371 1.00 27.46  ? 43  THR D CA  1 
ATOM   8454  C C   . THR D 1 78  ? 155.280 112.829 106.610 1.00 27.64  ? 43  THR D C   1 
ATOM   8455  O O   . THR D 1 78  ? 155.852 111.880 107.152 1.00 34.21  ? 43  THR D O   1 
ATOM   8456  C CB  . THR D 1 78  ? 152.968 112.377 105.796 1.00 27.16  ? 43  THR D CB  1 
ATOM   8457  O OG1 . THR D 1 78  ? 152.907 111.218 106.635 1.00 33.47  ? 43  THR D OG1 1 
ATOM   8458  C CG2 . THR D 1 78  ? 152.084 112.160 104.579 1.00 29.94  ? 43  THR D CG2 1 
ATOM   8459  N N   . ASP D 1 79  ? 155.367 114.081 107.048 1.00 24.44  ? 44  ASP D N   1 
ATOM   8460  C CA  . ASP D 1 79  ? 155.933 114.412 108.347 1.00 25.16  ? 44  ASP D CA  1 
ATOM   8461  C C   . ASP D 1 79  ? 155.257 115.673 108.862 1.00 22.87  ? 44  ASP D C   1 
ATOM   8462  O O   . ASP D 1 79  ? 154.723 116.474 108.091 1.00 22.14  ? 44  ASP D O   1 
ATOM   8463  C CB  . ASP D 1 79  ? 157.455 114.586 108.281 1.00 28.40  ? 44  ASP D CB  1 
ATOM   8464  C CG  . ASP D 1 79  ? 157.886 115.559 107.208 1.00 30.61  ? 44  ASP D CG  1 
ATOM   8465  O OD1 . ASP D 1 79  ? 157.517 115.354 106.033 1.00 31.84  ? 44  ASP D OD1 1 
ATOM   8466  O OD2 . ASP D 1 79  ? 158.603 116.526 107.539 1.00 34.15  ? 44  ASP D OD2 1 
ATOM   8467  N N   . ILE D 1 80  ? 155.283 115.842 110.180 1.00 23.06  ? 45  ILE D N   1 
ATOM   8468  C CA  . ILE D 1 80  ? 154.576 116.924 110.850 1.00 19.30  ? 45  ILE D CA  1 
ATOM   8469  C C   . ILE D 1 80  ? 155.545 117.640 111.776 1.00 22.75  ? 45  ILE D C   1 
ATOM   8470  O O   . ILE D 1 80  ? 156.339 117.002 112.475 1.00 29.01  ? 45  ILE D O   1 
ATOM   8471  C CB  . ILE D 1 80  ? 153.356 116.403 111.640 1.00 20.65  ? 45  ILE D CB  1 
ATOM   8472  C CG1 . ILE D 1 80  ? 152.352 115.734 110.702 1.00 19.05  ? 45  ILE D CG1 1 
ATOM   8473  C CG2 . ILE D 1 80  ? 152.692 117.523 112.421 1.00 22.64  ? 45  ILE D CG2 1 
ATOM   8474  C CD1 . ILE D 1 80  ? 151.133 115.195 111.410 1.00 20.35  ? 45  ILE D CD1 1 
ATOM   8475  N N   . PHE D 1 81  ? 155.483 118.970 111.774 1.00 21.91  ? 46  PHE D N   1 
ATOM   8476  C CA  . PHE D 1 81  ? 156.212 119.805 112.721 1.00 22.78  ? 46  PHE D CA  1 
ATOM   8477  C C   . PHE D 1 81  ? 155.186 120.587 113.531 1.00 22.84  ? 46  PHE D C   1 
ATOM   8478  O O   . PHE D 1 81  ? 154.464 121.424 112.981 1.00 25.57  ? 46  PHE D O   1 
ATOM   8479  C CB  . PHE D 1 81  ? 157.168 120.740 111.982 1.00 20.60  ? 46  PHE D CB  1 
ATOM   8480  C CG  . PHE D 1 81  ? 158.031 121.569 112.882 1.00 24.91  ? 46  PHE D CG  1 
ATOM   8481  C CD1 . PHE D 1 81  ? 159.194 121.049 113.418 1.00 29.83  ? 46  PHE D CD1 1 
ATOM   8482  C CD2 . PHE D 1 81  ? 157.685 122.874 113.183 1.00 23.85  ? 46  PHE D CD2 1 
ATOM   8483  C CE1 . PHE D 1 81  ? 159.993 121.812 114.243 1.00 30.43  ? 46  PHE D CE1 1 
ATOM   8484  C CE2 . PHE D 1 81  ? 158.479 123.641 114.008 1.00 27.97  ? 46  PHE D CE2 1 
ATOM   8485  C CZ  . PHE D 1 81  ? 159.634 123.110 114.539 1.00 30.28  ? 46  PHE D CZ  1 
ATOM   8486  N N   . VAL D 1 82  ? 155.120 120.317 114.830 1.00 19.66  ? 47  VAL D N   1 
ATOM   8487  C CA  . VAL D 1 82  ? 154.122 120.928 115.700 1.00 19.09  ? 47  VAL D CA  1 
ATOM   8488  C C   . VAL D 1 82  ? 154.683 122.236 116.244 1.00 21.04  ? 47  VAL D C   1 
ATOM   8489  O O   . VAL D 1 82  ? 155.559 122.231 117.111 1.00 26.69  ? 47  VAL D O   1 
ATOM   8490  C CB  . VAL D 1 82  ? 153.722 119.983 116.838 1.00 23.86  ? 47  VAL D CB  1 
ATOM   8491  C CG1 . VAL D 1 82  ? 152.667 120.630 117.718 1.00 24.25  ? 47  VAL D CG1 1 
ATOM   8492  C CG2 . VAL D 1 82  ? 153.214 118.667 116.276 1.00 24.51  ? 47  VAL D CG2 1 
ATOM   8493  N N   . THR D 1 83  ? 154.183 123.363 115.733 1.00 21.08  ? 48  THR D N   1 
ATOM   8494  C CA  . THR D 1 83  ? 154.634 124.653 116.246 1.00 23.43  ? 48  THR D CA  1 
ATOM   8495  C C   . THR D 1 83  ? 154.091 124.908 117.644 1.00 25.70  ? 48  THR D C   1 
ATOM   8496  O O   . THR D 1 83  ? 154.795 125.451 118.502 1.00 30.39  ? 48  THR D O   1 
ATOM   8497  C CB  . THR D 1 83  ? 154.217 125.779 115.305 1.00 22.95  ? 48  THR D CB  1 
ATOM   8498  O OG1 . THR D 1 83  ? 152.806 125.995 115.413 1.00 29.37  ? 48  THR D OG1 1 
ATOM   8499  C CG2 . THR D 1 83  ? 154.556 125.418 113.887 1.00 19.08  ? 48  THR D CG2 1 
ATOM   8500  N N   . SER D 1 84  ? 152.838 124.531 117.889 1.00 23.78  ? 49  SER D N   1 
ATOM   8501  C CA  . SER D 1 84  ? 152.225 124.725 119.196 1.00 25.51  ? 49  SER D CA  1 
ATOM   8502  C C   . SER D 1 84  ? 151.123 123.698 119.387 1.00 24.58  ? 49  SER D C   1 
ATOM   8503  O O   . SER D 1 84  ? 150.205 123.615 118.566 1.00 24.84  ? 49  SER D O   1 
ATOM   8504  C CB  . SER D 1 84  ? 151.660 126.136 119.325 1.00 28.66  ? 49  SER D CB  1 
ATOM   8505  O OG  . SER D 1 84  ? 150.531 126.306 118.487 1.00 26.05  ? 49  SER D OG  1 
ATOM   8506  N N   . PHE D 1 85  ? 151.206 122.932 120.471 1.00 22.97  ? 50  PHE D N   1 
ATOM   8507  C CA  . PHE D 1 85  ? 150.141 122.011 120.857 1.00 20.13  ? 50  PHE D CA  1 
ATOM   8508  C C   . PHE D 1 85  ? 149.121 122.798 121.669 1.00 22.32  ? 50  PHE D C   1 
ATOM   8509  O O   . PHE D 1 85  ? 149.290 122.995 122.874 1.00 26.65  ? 50  PHE D O   1 
ATOM   8510  C CB  . PHE D 1 85  ? 150.699 120.830 121.641 1.00 22.92  ? 50  PHE D CB  1 
ATOM   8511  C CG  . PHE D 1 85  ? 149.697 119.742 121.886 1.00 23.80  ? 50  PHE D CG  1 
ATOM   8512  C CD1 . PHE D 1 85  ? 149.456 118.776 120.927 1.00 22.04  ? 50  PHE D CD1 1 
ATOM   8513  C CD2 . PHE D 1 85  ? 148.992 119.688 123.074 1.00 27.73  ? 50  PHE D CD2 1 
ATOM   8514  C CE1 . PHE D 1 85  ? 148.533 117.777 121.151 1.00 23.33  ? 50  PHE D CE1 1 
ATOM   8515  C CE2 . PHE D 1 85  ? 148.067 118.692 123.303 1.00 27.30  ? 50  PHE D CE2 1 
ATOM   8516  C CZ  . PHE D 1 85  ? 147.837 117.736 122.340 1.00 26.29  ? 50  PHE D CZ  1 
ATOM   8517  N N   . GLY D 1 86  ? 148.071 123.272 121.000 1.00 22.69  ? 51  GLY D N   1 
ATOM   8518  C CA  . GLY D 1 86  ? 147.176 124.263 121.552 1.00 23.87  ? 51  GLY D CA  1 
ATOM   8519  C C   . GLY D 1 86  ? 146.437 123.806 122.794 1.00 25.06  ? 51  GLY D C   1 
ATOM   8520  O O   . GLY D 1 86  ? 146.685 122.725 123.335 1.00 25.44  ? 51  GLY D O   1 
ATOM   8521  N N   . PRO D 1 87  ? 145.487 124.617 123.254 1.00 24.90  ? 52  PRO D N   1 
ATOM   8522  C CA  . PRO D 1 87  ? 144.731 124.256 124.457 1.00 27.88  ? 52  PRO D CA  1 
ATOM   8523  C C   . PRO D 1 87  ? 143.872 123.020 124.246 1.00 30.25  ? 52  PRO D C   1 
ATOM   8524  O O   . PRO D 1 87  ? 143.419 122.724 123.138 1.00 29.96  ? 52  PRO D O   1 
ATOM   8525  C CB  . PRO D 1 87  ? 143.866 125.494 124.716 1.00 24.72  ? 52  PRO D CB  1 
ATOM   8526  C CG  . PRO D 1 87  ? 143.741 126.151 123.383 1.00 24.17  ? 52  PRO D CG  1 
ATOM   8527  C CD  . PRO D 1 87  ? 145.038 125.894 122.674 1.00 21.93  ? 52  PRO D CD  1 
ATOM   8528  N N   . VAL D 1 88  ? 143.653 122.297 125.340 1.00 31.52  ? 53  VAL D N   1 
ATOM   8529  C CA  . VAL D 1 88  ? 142.787 121.125 125.374 1.00 28.63  ? 53  VAL D CA  1 
ATOM   8530  C C   . VAL D 1 88  ? 141.516 121.506 126.116 1.00 32.50  ? 53  VAL D C   1 
ATOM   8531  O O   . VAL D 1 88  ? 141.578 122.080 127.209 1.00 36.49  ? 53  VAL D O   1 
ATOM   8532  C CB  . VAL D 1 88  ? 143.484 119.929 126.045 1.00 25.66  ? 53  VAL D CB  1 
ATOM   8533  C CG1 . VAL D 1 88  ? 142.540 118.746 126.135 1.00 23.19  ? 53  VAL D CG1 1 
ATOM   8534  C CG2 . VAL D 1 88  ? 144.739 119.552 125.279 1.00 25.83  ? 53  VAL D CG2 1 
ATOM   8535  N N   . SER D 1 89  ? 140.366 121.188 125.528 1.00 32.84  ? 54  SER D N   1 
ATOM   8536  C CA  . SER D 1 89  ? 139.068 121.535 126.096 1.00 37.79  ? 54  SER D CA  1 
ATOM   8537  C C   . SER D 1 89  ? 138.391 120.270 126.609 1.00 40.48  ? 54  SER D C   1 
ATOM   8538  O O   . SER D 1 89  ? 137.911 119.451 125.820 1.00 38.29  ? 54  SER D O   1 
ATOM   8539  C CB  . SER D 1 89  ? 138.199 122.242 125.058 1.00 39.46  ? 54  SER D CB  1 
ATOM   8540  O OG  . SER D 1 89  ? 136.981 122.684 125.629 1.00 45.39  ? 54  SER D OG  1 
ATOM   8541  N N   . ASP D 1 90  ? 138.355 120.118 127.936 1.00 45.47  ? 55  ASP D N   1 
ATOM   8542  C CA  . ASP D 1 90  ? 137.676 118.980 128.548 1.00 46.30  ? 55  ASP D CA  1 
ATOM   8543  C C   . ASP D 1 90  ? 136.170 119.026 128.324 1.00 51.00  ? 55  ASP D C   1 
ATOM   8544  O O   . ASP D 1 90  ? 135.534 117.975 128.190 1.00 50.88  ? 55  ASP D O   1 
ATOM   8545  C CB  . ASP D 1 90  ? 137.981 118.923 130.044 1.00 42.31  ? 55  ASP D CB  1 
ATOM   8546  C CG  . ASP D 1 90  ? 139.462 119.022 130.340 1.00 42.59  ? 55  ASP D CG  1 
ATOM   8547  O OD1 . ASP D 1 90  ? 140.266 118.496 129.543 1.00 41.12  ? 55  ASP D OD1 1 
ATOM   8548  O OD2 . ASP D 1 90  ? 139.822 119.624 131.373 1.00 44.09  ? 55  ASP D OD2 1 
ATOM   8549  N N   . HIS D 1 91  ? 135.583 120.224 128.294 1.00 52.52  ? 56  HIS D N   1 
ATOM   8550  C CA  . HIS D 1 91  ? 134.143 120.343 128.093 1.00 52.13  ? 56  HIS D CA  1 
ATOM   8551  C C   . HIS D 1 91  ? 133.740 119.846 126.711 1.00 46.04  ? 56  HIS D C   1 
ATOM   8552  O O   . HIS D 1 91  ? 132.803 119.052 126.570 1.00 51.26  ? 56  HIS D O   1 
ATOM   8553  C CB  . HIS D 1 91  ? 133.709 121.795 128.291 1.00 53.30  ? 56  HIS D CB  1 
ATOM   8554  C CG  . HIS D 1 91  ? 133.932 122.307 129.679 1.00 61.10  ? 56  HIS D CG  1 
ATOM   8555  N ND1 . HIS D 1 91  ? 132.981 122.209 130.671 1.00 61.56  ? 56  HIS D ND1 1 
ATOM   8556  C CD2 . HIS D 1 91  ? 135.001 122.918 130.243 1.00 60.53  ? 56  HIS D CD2 1 
ATOM   8557  C CE1 . HIS D 1 91  ? 133.453 122.738 131.785 1.00 61.27  ? 56  HIS D CE1 1 
ATOM   8558  N NE2 . HIS D 1 91  ? 134.678 123.175 131.552 1.00 62.25  ? 56  HIS D NE2 1 
ATOM   8559  N N   . ASP D 1 92  ? 134.445 120.298 125.677 1.00 37.87  ? 57  ASP D N   1 
ATOM   8560  C CA  . ASP D 1 92  ? 134.182 119.862 124.314 1.00 40.70  ? 57  ASP D CA  1 
ATOM   8561  C C   . ASP D 1 92  ? 134.880 118.554 123.962 1.00 44.19  ? 57  ASP D C   1 
ATOM   8562  O O   . ASP D 1 92  ? 134.578 117.980 122.910 1.00 40.35  ? 57  ASP D O   1 
ATOM   8563  C CB  . ASP D 1 92  ? 134.599 120.951 123.324 1.00 43.25  ? 57  ASP D CB  1 
ATOM   8564  C CG  . ASP D 1 92  ? 133.822 122.237 123.513 1.00 45.78  ? 57  ASP D CG  1 
ATOM   8565  O OD1 . ASP D 1 92  ? 132.691 122.176 124.038 1.00 47.81  ? 57  ASP D OD1 1 
ATOM   8566  O OD2 . ASP D 1 92  ? 134.340 123.308 123.135 1.00 44.24  ? 57  ASP D OD2 1 
ATOM   8567  N N   . MET D 1 93  ? 135.789 118.073 124.811 1.00 45.99  ? 58  MET D N   1 
ATOM   8568  C CA  . MET D 1 93  ? 136.567 116.860 124.556 1.00 41.99  ? 58  MET D CA  1 
ATOM   8569  C C   . MET D 1 93  ? 137.259 116.952 123.197 1.00 40.94  ? 58  MET D C   1 
ATOM   8570  O O   . MET D 1 93  ? 137.055 116.139 122.295 1.00 39.96  ? 58  MET D O   1 
ATOM   8571  C CB  . MET D 1 93  ? 135.683 115.614 124.646 1.00 39.03  ? 58  MET D CB  1 
ATOM   8572  C CG  . MET D 1 93  ? 135.183 115.313 126.049 1.00 44.24  ? 58  MET D CG  1 
ATOM   8573  S SD  . MET D 1 93  ? 134.533 113.643 126.218 1.00 62.17  ? 58  MET D SD  1 
ATOM   8574  C CE  . MET D 1 93  ? 134.134 113.613 127.962 1.00 54.04  ? 58  MET D CE  1 
ATOM   8575  N N   . GLU D 1 94  ? 138.098 117.979 123.078 1.00 37.61  ? 59  GLU D N   1 
ATOM   8576  C CA  . GLU D 1 94  ? 138.861 118.239 121.868 1.00 31.55  ? 59  GLU D CA  1 
ATOM   8577  C C   . GLU D 1 94  ? 140.114 119.019 122.235 1.00 31.04  ? 59  GLU D C   1 
ATOM   8578  O O   . GLU D 1 94  ? 140.254 119.518 123.354 1.00 34.69  ? 59  GLU D O   1 
ATOM   8579  C CB  . GLU D 1 94  ? 138.021 119.005 120.848 1.00 31.10  ? 59  GLU D CB  1 
ATOM   8580  C CG  . GLU D 1 94  ? 137.514 120.329 121.372 1.00 35.87  ? 59  GLU D CG  1 
ATOM   8581  C CD  . GLU D 1 94  ? 137.018 121.230 120.273 1.00 37.34  ? 59  GLU D CD  1 
ATOM   8582  O OE1 . GLU D 1 94  ? 137.311 120.937 119.097 1.00 37.22  ? 59  GLU D OE1 1 
ATOM   8583  O OE2 . GLU D 1 94  ? 136.336 122.229 120.581 1.00 37.44  ? 59  GLU D OE2 1 
ATOM   8584  N N   . TYR D 1 95  ? 141.032 119.120 121.276 1.00 28.20  ? 60  TYR D N   1 
ATOM   8585  C CA  . TYR D 1 95  ? 142.248 119.896 121.459 1.00 25.81  ? 60  TYR D CA  1 
ATOM   8586  C C   . TYR D 1 95  ? 142.604 120.584 120.150 1.00 23.31  ? 60  TYR D C   1 
ATOM   8587  O O   . TYR D 1 95  ? 142.164 120.181 119.072 1.00 23.69  ? 60  TYR D O   1 
ATOM   8588  C CB  . TYR D 1 95  ? 143.427 119.027 121.918 1.00 24.26  ? 60  TYR D CB  1 
ATOM   8589  C CG  . TYR D 1 95  ? 143.863 117.991 120.907 1.00 23.91  ? 60  TYR D CG  1 
ATOM   8590  C CD1 . TYR D 1 95  ? 143.176 116.796 120.761 1.00 25.13  ? 60  TYR D CD1 1 
ATOM   8591  C CD2 . TYR D 1 95  ? 144.966 118.213 120.097 1.00 23.77  ? 60  TYR D CD2 1 
ATOM   8592  C CE1 . TYR D 1 95  ? 143.575 115.855 119.836 1.00 23.80  ? 60  TYR D CE1 1 
ATOM   8593  C CE2 . TYR D 1 95  ? 145.372 117.279 119.172 1.00 23.26  ? 60  TYR D CE2 1 
ATOM   8594  C CZ  . TYR D 1 95  ? 144.674 116.103 119.044 1.00 22.48  ? 60  TYR D CZ  1 
ATOM   8595  O OH  . TYR D 1 95  ? 145.083 115.172 118.121 1.00 24.64  ? 60  TYR D OH  1 
ATOM   8596  N N   . THR D 1 96  ? 143.410 121.635 120.261 1.00 21.77  ? 61  THR D N   1 
ATOM   8597  C CA  . THR D 1 96  ? 143.913 122.382 119.118 1.00 19.98  ? 61  THR D CA  1 
ATOM   8598  C C   . THR D 1 96  ? 145.390 122.063 118.918 1.00 20.08  ? 61  THR D C   1 
ATOM   8599  O O   . THR D 1 96  ? 146.125 121.861 119.889 1.00 23.11  ? 61  THR D O   1 
ATOM   8600  C CB  . THR D 1 96  ? 143.712 123.888 119.325 1.00 22.45  ? 61  THR D CB  1 
ATOM   8601  O OG1 . THR D 1 96  ? 142.310 124.174 119.397 1.00 27.63  ? 61  THR D OG1 1 
ATOM   8602  C CG2 . THR D 1 96  ? 144.308 124.686 118.175 1.00 25.92  ? 61  THR D CG2 1 
ATOM   8603  N N   . ILE D 1 97  ? 145.817 121.991 117.660 1.00 19.19  ? 62  ILE D N   1 
ATOM   8604  C CA  . ILE D 1 97  ? 147.210 121.725 117.320 1.00 21.24  ? 62  ILE D CA  1 
ATOM   8605  C C   . ILE D 1 97  ? 147.574 122.524 116.074 1.00 20.73  ? 62  ILE D C   1 
ATOM   8606  O O   . ILE D 1 97  ? 146.855 122.484 115.070 1.00 23.61  ? 62  ILE D O   1 
ATOM   8607  C CB  . ILE D 1 97  ? 147.475 120.216 117.123 1.00 18.25  ? 62  ILE D CB  1 
ATOM   8608  C CG1 . ILE D 1 97  ? 148.968 119.949 116.944 1.00 19.38  ? 62  ILE D CG1 1 
ATOM   8609  C CG2 . ILE D 1 97  ? 146.656 119.638 115.973 1.00 16.18  ? 62  ILE D CG2 1 
ATOM   8610  C CD1 . ILE D 1 97  ? 149.299 118.491 116.744 1.00 22.22  ? 62  ILE D CD1 1 
ATOM   8611  N N   . ASP D 1 98  ? 148.656 123.296 116.156 1.00 19.15  ? 63  ASP D N   1 
ATOM   8612  C CA  . ASP D 1 98  ? 149.153 124.072 115.027 1.00 18.94  ? 63  ASP D CA  1 
ATOM   8613  C C   . ASP D 1 98  ? 150.355 123.350 114.431 1.00 19.69  ? 63  ASP D C   1 
ATOM   8614  O O   . ASP D 1 98  ? 151.355 123.129 115.122 1.00 25.33  ? 63  ASP D O   1 
ATOM   8615  C CB  . ASP D 1 98  ? 149.543 125.482 115.468 1.00 26.35  ? 63  ASP D CB  1 
ATOM   8616  C CG  . ASP D 1 98  ? 148.360 126.291 115.961 1.00 34.51  ? 63  ASP D CG  1 
ATOM   8617  O OD1 . ASP D 1 98  ? 147.860 125.999 117.068 1.00 27.90  ? 63  ASP D OD1 1 
ATOM   8618  O OD2 . ASP D 1 98  ? 147.934 127.224 115.249 1.00 44.67  ? 63  ASP D OD2 1 
ATOM   8619  N N   . VAL D 1 99  ? 150.259 122.982 113.153 1.00 16.65  ? 64  VAL D N   1 
ATOM   8620  C CA  . VAL D 1 99  ? 151.238 122.111 112.518 1.00 14.91  ? 64  VAL D CA  1 
ATOM   8621  C C   . VAL D 1 99  ? 151.693 122.689 111.185 1.00 13.29  ? 64  VAL D C   1 
ATOM   8622  O O   . VAL D 1 99  ? 151.010 123.503 110.561 1.00 16.77  ? 64  VAL D O   1 
ATOM   8623  C CB  . VAL D 1 99  ? 150.694 120.681 112.302 1.00 16.20  ? 64  VAL D CB  1 
ATOM   8624  C CG1 . VAL D 1 99  ? 150.242 120.076 113.610 1.00 17.82  ? 64  VAL D CG1 1 
ATOM   8625  C CG2 . VAL D 1 99  ? 149.555 120.690 111.298 1.00 14.53  ? 64  VAL D CG2 1 
ATOM   8626  N N   . PHE D 1 100 ? 152.878 122.253 110.762 1.00 12.88  ? 65  PHE D N   1 
ATOM   8627  C CA  . PHE D 1 100 ? 153.317 122.338 109.370 1.00 13.96  ? 65  PHE D CA  1 
ATOM   8628  C C   . PHE D 1 100 ? 153.193 120.932 108.801 1.00 15.92  ? 65  PHE D C   1 
ATOM   8629  O O   . PHE D 1 100 ? 154.013 120.057 109.088 1.00 18.27  ? 65  PHE D O   1 
ATOM   8630  C CB  . PHE D 1 100 ? 154.739 122.873 109.229 1.00 14.53  ? 65  PHE D CB  1 
ATOM   8631  C CG  . PHE D 1 100 ? 154.849 124.363 109.355 1.00 16.20  ? 65  PHE D CG  1 
ATOM   8632  C CD1 . PHE D 1 100 ? 154.671 125.169 108.245 1.00 15.83  ? 65  PHE D CD1 1 
ATOM   8633  C CD2 . PHE D 1 100 ? 155.149 124.959 110.562 1.00 19.85  ? 65  PHE D CD2 1 
ATOM   8634  C CE1 . PHE D 1 100 ? 154.775 126.541 108.340 1.00 13.99  ? 65  PHE D CE1 1 
ATOM   8635  C CE2 . PHE D 1 100 ? 155.255 126.334 110.663 1.00 17.78  ? 65  PHE D CE2 1 
ATOM   8636  C CZ  . PHE D 1 100 ? 155.067 127.124 109.551 1.00 15.13  ? 65  PHE D CZ  1 
ATOM   8637  N N   . PHE D 1 101 ? 152.162 120.718 107.992 1.00 17.18  ? 66  PHE D N   1 
ATOM   8638  C CA  . PHE D 1 101 ? 151.854 119.403 107.452 1.00 17.42  ? 66  PHE D CA  1 
ATOM   8639  C C   . PHE D 1 101 ? 152.564 119.235 106.116 1.00 16.16  ? 66  PHE D C   1 
ATOM   8640  O O   . PHE D 1 101 ? 152.184 119.860 105.121 1.00 19.50  ? 66  PHE D O   1 
ATOM   8641  C CB  . PHE D 1 101 ? 150.344 119.241 107.289 1.00 16.27  ? 66  PHE D CB  1 
ATOM   8642  C CG  . PHE D 1 101 ? 149.917 117.854 106.918 1.00 14.42  ? 66  PHE D CG  1 
ATOM   8643  C CD1 . PHE D 1 101 ? 150.192 116.785 107.751 1.00 15.53  ? 66  PHE D CD1 1 
ATOM   8644  C CD2 . PHE D 1 101 ? 149.236 117.620 105.739 1.00 16.01  ? 66  PHE D CD2 1 
ATOM   8645  C CE1 . PHE D 1 101 ? 149.800 115.510 107.411 1.00 17.62  ? 66  PHE D CE1 1 
ATOM   8646  C CE2 . PHE D 1 101 ? 148.840 116.348 105.395 1.00 18.91  ? 66  PHE D CE2 1 
ATOM   8647  C CZ  . PHE D 1 101 ? 149.123 115.292 106.231 1.00 18.58  ? 66  PHE D CZ  1 
ATOM   8648  N N   . ARG D 1 102 ? 153.593 118.393 106.098 1.00 15.85  ? 67  ARG D N   1 
ATOM   8649  C CA  . ARG D 1 102 ? 154.419 118.173 104.920 1.00 16.60  ? 67  ARG D CA  1 
ATOM   8650  C C   . ARG D 1 102 ? 154.052 116.836 104.299 1.00 19.77  ? 67  ARG D C   1 
ATOM   8651  O O   . ARG D 1 102 ? 154.039 115.811 104.987 1.00 25.68  ? 67  ARG D O   1 
ATOM   8652  C CB  . ARG D 1 102 ? 155.904 118.208 105.281 1.00 16.63  ? 67  ARG D CB  1 
ATOM   8653  C CG  . ARG D 1 102 ? 156.382 119.559 105.766 1.00 18.98  ? 67  ARG D CG  1 
ATOM   8654  C CD  . ARG D 1 102 ? 157.666 119.444 106.563 1.00 23.28  ? 67  ARG D CD  1 
ATOM   8655  N NE  . ARG D 1 102 ? 158.090 120.736 107.089 1.00 26.29  ? 67  ARG D NE  1 
ATOM   8656  C CZ  . ARG D 1 102 ? 158.962 120.895 108.075 1.00 30.73  ? 67  ARG D CZ  1 
ATOM   8657  N NH1 . ARG D 1 102 ? 159.514 119.859 108.684 1.00 24.71  ? 67  ARG D NH1 1 
ATOM   8658  N NH2 . ARG D 1 102 ? 159.284 122.126 108.463 1.00 38.68  ? 67  ARG D NH2 1 
ATOM   8659  N N   . GLN D 1 103 ? 153.751 116.851 103.006 1.00 17.56  ? 68  GLN D N   1 
ATOM   8660  C CA  . GLN D 1 103 ? 153.470 115.650 102.238 1.00 17.99  ? 68  GLN D CA  1 
ATOM   8661  C C   . GLN D 1 103 ? 154.436 115.566 101.071 1.00 20.08  ? 68  GLN D C   1 
ATOM   8662  O O   . GLN D 1 103 ? 154.740 116.578 100.434 1.00 24.56  ? 68  GLN D O   1 
ATOM   8663  C CB  . GLN D 1 103 ? 152.041 115.639 101.694 1.00 18.85  ? 68  GLN D CB  1 
ATOM   8664  C CG  . GLN D 1 103 ? 150.955 115.544 102.734 1.00 22.43  ? 68  GLN D CG  1 
ATOM   8665  C CD  . GLN D 1 103 ? 149.577 115.675 102.120 1.00 26.10  ? 68  GLN D CD  1 
ATOM   8666  O OE1 . GLN D 1 103 ? 148.832 114.701 102.024 1.00 25.13  ? 68  GLN D OE1 1 
ATOM   8667  N NE2 . GLN D 1 103 ? 149.234 116.882 101.692 1.00 25.26  ? 68  GLN D NE2 1 
ATOM   8668  N N   . SER D 1 104 ? 154.924 114.362 100.794 1.00 20.89  ? 69  SER D N   1 
ATOM   8669  C CA  . SER D 1 104 ? 155.878 114.179 99.714  1.00 21.86  ? 69  SER D CA  1 
ATOM   8670  C C   . SER D 1 104 ? 155.478 112.944 98.928  1.00 23.56  ? 69  SER D C   1 
ATOM   8671  O O   . SER D 1 104 ? 155.204 111.892 99.510  1.00 28.75  ? 69  SER D O   1 
ATOM   8672  C CB  . SER D 1 104 ? 157.306 114.039 100.249 1.00 25.14  ? 69  SER D CB  1 
ATOM   8673  O OG  . SER D 1 104 ? 158.222 113.795 99.197  1.00 27.05  ? 69  SER D OG  1 
ATOM   8674  N N   . TRP D 1 105 ? 155.442 113.083 97.608  1.00 23.78  ? 70  TRP D N   1 
ATOM   8675  C CA  . TRP D 1 105 ? 155.106 111.992 96.710  1.00 27.44  ? 70  TRP D CA  1 
ATOM   8676  C C   . TRP D 1 105 ? 155.774 112.272 95.373  1.00 31.03  ? 70  TRP D C   1 
ATOM   8677  O O   . TRP D 1 105 ? 156.376 113.329 95.171  1.00 33.47  ? 70  TRP D O   1 
ATOM   8678  C CB  . TRP D 1 105 ? 153.588 111.825 96.579  1.00 33.08  ? 70  TRP D CB  1 
ATOM   8679  C CG  . TRP D 1 105 ? 152.898 112.929 95.840  1.00 30.70  ? 70  TRP D CG  1 
ATOM   8680  C CD1 . TRP D 1 105 ? 152.501 112.916 94.537  1.00 30.45  ? 70  TRP D CD1 1 
ATOM   8681  C CD2 . TRP D 1 105 ? 152.507 114.204 96.365  1.00 27.58  ? 70  TRP D CD2 1 
ATOM   8682  N NE1 . TRP D 1 105 ? 151.893 114.103 94.215  1.00 29.88  ? 70  TRP D NE1 1 
ATOM   8683  C CE2 . TRP D 1 105 ? 151.884 114.911 95.321  1.00 27.35  ? 70  TRP D CE2 1 
ATOM   8684  C CE3 . TRP D 1 105 ? 152.625 114.815 97.616  1.00 26.34  ? 70  TRP D CE3 1 
ATOM   8685  C CZ2 . TRP D 1 105 ? 151.383 116.199 95.488  1.00 28.57  ? 70  TRP D CZ2 1 
ATOM   8686  C CZ3 . TRP D 1 105 ? 152.130 116.094 97.778  1.00 25.46  ? 70  TRP D CZ3 1 
ATOM   8687  C CH2 . TRP D 1 105 ? 151.517 116.772 96.720  1.00 26.07  ? 70  TRP D CH2 1 
ATOM   8688  N N   . LYS D 1 106 ? 155.664 111.321 94.454  1.00 35.96  ? 71  LYS D N   1 
ATOM   8689  C CA  . LYS D 1 106 ? 156.323 111.419 93.161  1.00 42.33  ? 71  LYS D CA  1 
ATOM   8690  C C   . LYS D 1 106 ? 155.259 111.480 92.077  1.00 45.75  ? 71  LYS D C   1 
ATOM   8691  O O   . LYS D 1 106 ? 154.322 110.675 92.074  1.00 53.14  ? 71  LYS D O   1 
ATOM   8692  C CB  . LYS D 1 106 ? 157.263 110.234 92.927  1.00 44.19  ? 71  LYS D CB  1 
ATOM   8693  C CG  . LYS D 1 106 ? 158.264 110.452 91.806  1.00 45.28  ? 71  LYS D CG  1 
ATOM   8694  C CD  . LYS D 1 106 ? 159.367 109.409 91.840  1.00 48.02  ? 71  LYS D CD  1 
ATOM   8695  C CE  . LYS D 1 106 ? 160.462 109.734 90.840  1.00 47.88  ? 71  LYS D CE  1 
ATOM   8696  N NZ  . LYS D 1 106 ? 161.544 108.713 90.856  1.00 43.45  ? 71  LYS D NZ  1 
ATOM   8697  N N   . ASP D 1 107 ? 155.409 112.434 91.161  1.00 44.74  ? 72  ASP D N   1 
ATOM   8698  C CA  . ASP D 1 107 ? 154.527 112.579 90.004  1.00 48.30  ? 72  ASP D CA  1 
ATOM   8699  C C   . ASP D 1 107 ? 155.413 112.735 88.773  1.00 54.53  ? 72  ASP D C   1 
ATOM   8700  O O   . ASP D 1 107 ? 155.944 113.820 88.519  1.00 56.25  ? 72  ASP D O   1 
ATOM   8701  C CB  . ASP D 1 107 ? 153.584 113.765 90.174  1.00 45.83  ? 72  ASP D CB  1 
ATOM   8702  C CG  . ASP D 1 107 ? 152.448 113.757 89.170  1.00 48.87  ? 72  ASP D CG  1 
ATOM   8703  O OD1 . ASP D 1 107 ? 152.495 112.958 88.211  1.00 49.05  ? 72  ASP D OD1 1 
ATOM   8704  O OD2 . ASP D 1 107 ? 151.500 114.549 89.345  1.00 53.30  ? 72  ASP D OD2 1 
ATOM   8705  N N   . GLU D 1 108 ? 155.579 111.647 88.018  1.00 57.61  ? 73  GLU D N   1 
ATOM   8706  C CA  . GLU D 1 108 ? 156.452 111.673 86.850  1.00 62.05  ? 73  GLU D CA  1 
ATOM   8707  C C   . GLU D 1 108 ? 155.977 112.656 85.788  1.00 63.87  ? 73  GLU D C   1 
ATOM   8708  O O   . GLU D 1 108 ? 156.787 113.104 84.968  1.00 65.33  ? 73  GLU D O   1 
ATOM   8709  C CB  . GLU D 1 108 ? 156.537 110.272 86.245  1.00 62.43  ? 73  GLU D CB  1 
ATOM   8710  C CG  . GLU D 1 108 ? 157.138 109.226 87.165  1.00 68.11  ? 73  GLU D CG  1 
ATOM   8711  C CD  . GLU D 1 108 ? 157.069 107.830 86.578  1.00 80.21  ? 73  GLU D CD  1 
ATOM   8712  O OE1 . GLU D 1 108 ? 156.694 107.702 85.393  1.00 81.51  ? 73  GLU D OE1 1 
ATOM   8713  O OE2 . GLU D 1 108 ? 157.387 106.862 87.300  1.00 83.31  ? 73  GLU D OE2 1 
ATOM   8714  N N   . ARG D 1 109 ? 154.689 113.002 85.784  1.00 61.57  ? 74  ARG D N   1 
ATOM   8715  C CA  . ARG D 1 109 ? 154.156 113.980 84.844  1.00 57.13  ? 74  ARG D CA  1 
ATOM   8716  C C   . ARG D 1 109 ? 154.709 115.383 85.055  1.00 60.02  ? 74  ARG D C   1 
ATOM   8717  O O   . ARG D 1 109 ? 154.542 116.231 84.172  1.00 63.34  ? 74  ARG D O   1 
ATOM   8718  C CB  . ARG D 1 109 ? 152.631 114.003 84.948  1.00 52.57  ? 74  ARG D CB  1 
ATOM   8719  C CG  . ARG D 1 109 ? 151.966 112.714 84.500  1.00 47.29  ? 74  ARG D CG  1 
ATOM   8720  C CD  . ARG D 1 109 ? 150.470 112.740 84.766  1.00 48.17  ? 74  ARG D CD  1 
ATOM   8721  N NE  . ARG D 1 109 ? 150.187 112.834 86.193  1.00 48.92  ? 74  ARG D NE  1 
ATOM   8722  C CZ  . ARG D 1 109 ? 148.974 112.970 86.713  1.00 50.24  ? 74  ARG D CZ  1 
ATOM   8723  N NH1 . ARG D 1 109 ? 147.898 113.039 85.947  1.00 52.76  ? 74  ARG D NH1 1 
ATOM   8724  N NH2 . ARG D 1 109 ? 148.838 113.034 88.034  1.00 48.05  ? 74  ARG D NH2 1 
ATOM   8725  N N   . LEU D 1 110 ? 155.358 115.652 86.189  1.00 62.23  ? 75  LEU D N   1 
ATOM   8726  C CA  . LEU D 1 110 ? 155.886 116.975 86.499  1.00 69.06  ? 75  LEU D CA  1 
ATOM   8727  C C   . LEU D 1 110 ? 157.413 117.002 86.535  1.00 71.51  ? 75  LEU D C   1 
ATOM   8728  O O   . LEU D 1 110 ? 158.006 117.770 87.295  1.00 68.11  ? 75  LEU D O   1 
ATOM   8729  C CB  . LEU D 1 110 ? 155.316 117.475 87.825  1.00 62.86  ? 75  LEU D CB  1 
ATOM   8730  C CG  . LEU D 1 110 ? 153.806 117.713 87.864  1.00 56.72  ? 75  LEU D CG  1 
ATOM   8731  C CD1 . LEU D 1 110 ? 153.345 117.976 89.285  1.00 51.97  ? 75  LEU D CD1 1 
ATOM   8732  C CD2 . LEU D 1 110 ? 153.420 118.864 86.953  1.00 60.06  ? 75  LEU D CD2 1 
ATOM   8733  N N   . LYS D 1 111 ? 158.062 116.169 85.728  1.00 72.57  ? 76  LYS D N   1 
ATOM   8734  C CA  . LYS D 1 111 ? 159.501 116.283 85.555  1.00 71.79  ? 76  LYS D CA  1 
ATOM   8735  C C   . LYS D 1 111 ? 159.841 117.501 84.698  1.00 75.50  ? 76  LYS D C   1 
ATOM   8736  O O   . LYS D 1 111 ? 159.036 117.970 83.889  1.00 73.68  ? 76  LYS D O   1 
ATOM   8737  C CB  . LYS D 1 111 ? 160.068 115.010 84.929  1.00 70.14  ? 76  LYS D CB  1 
ATOM   8738  C CG  . LYS D 1 111 ? 159.996 113.801 85.846  1.00 62.90  ? 76  LYS D CG  1 
ATOM   8739  C CD  . LYS D 1 111 ? 160.533 112.552 85.175  1.00 61.67  ? 76  LYS D CD  1 
ATOM   8740  C CE  . LYS D 1 111 ? 160.486 111.363 86.121  1.00 64.69  ? 76  LYS D CE  1 
ATOM   8741  N NZ  . LYS D 1 111 ? 160.993 110.117 85.483  1.00 66.31  ? 76  LYS D NZ  1 
ATOM   8742  N N   . PHE D 1 112 ? 161.058 118.010 84.878  1.00 73.27  ? 77  PHE D N   1 
ATOM   8743  C CA  . PHE D 1 112 ? 161.508 119.152 84.096  1.00 72.23  ? 77  PHE D CA  1 
ATOM   8744  C C   . PHE D 1 112 ? 163.029 119.178 84.059  1.00 74.85  ? 77  PHE D C   1 
ATOM   8745  O O   . PHE D 1 112 ? 163.702 118.514 84.851  1.00 71.06  ? 77  PHE D O   1 
ATOM   8746  C CB  . PHE D 1 112 ? 160.953 120.464 84.668  1.00 69.90  ? 77  PHE D CB  1 
ATOM   8747  C CG  . PHE D 1 112 ? 161.413 120.764 86.073  1.00 72.74  ? 77  PHE D CG  1 
ATOM   8748  C CD1 . PHE D 1 112 ? 162.650 121.342 86.313  1.00 77.94  ? 77  PHE D CD1 1 
ATOM   8749  C CD2 . PHE D 1 112 ? 160.608 120.453 87.154  1.00 69.10  ? 77  PHE D CD2 1 
ATOM   8750  C CE1 . PHE D 1 112 ? 163.069 121.611 87.600  1.00 74.00  ? 77  PHE D CE1 1 
ATOM   8751  C CE2 . PHE D 1 112 ? 161.024 120.719 88.446  1.00 64.28  ? 77  PHE D CE2 1 
ATOM   8752  C CZ  . PHE D 1 112 ? 162.255 121.299 88.669  1.00 65.34  ? 77  PHE D CZ  1 
ATOM   8753  N N   . LYS D 1 113 ? 163.557 119.962 83.120  1.00 83.46  ? 78  LYS D N   1 
ATOM   8754  C CA  . LYS D 1 113 ? 164.985 120.209 82.989  1.00 86.23  ? 78  LYS D CA  1 
ATOM   8755  C C   . LYS D 1 113 ? 165.226 121.698 82.791  1.00 87.26  ? 78  LYS D C   1 
ATOM   8756  O O   . LYS D 1 113 ? 164.528 122.347 82.007  1.00 87.29  ? 78  LYS D O   1 
ATOM   8757  C CB  . LYS D 1 113 ? 165.583 119.420 81.816  1.00 83.11  ? 78  LYS D CB  1 
ATOM   8758  C CG  . LYS D 1 113 ? 165.348 117.919 81.900  1.00 79.45  ? 78  LYS D CG  1 
ATOM   8759  C CD  . LYS D 1 113 ? 165.919 117.191 80.695  1.00 74.26  ? 78  LYS D CD  1 
ATOM   8760  C CE  . LYS D 1 113 ? 165.674 115.694 80.797  1.00 70.33  ? 78  LYS D CE  1 
ATOM   8761  N NZ  . LYS D 1 113 ? 166.220 114.956 79.625  1.00 73.00  ? 78  LYS D NZ  1 
ATOM   8762  N N   . GLY D 1 114 ? 166.214 122.239 83.501  1.00 87.30  ? 79  GLY D N   1 
ATOM   8763  C CA  . GLY D 1 114 ? 166.513 123.648 83.411  1.00 90.82  ? 79  GLY D CA  1 
ATOM   8764  C C   . GLY D 1 114 ? 167.685 124.070 84.272  1.00 96.78  ? 79  GLY D C   1 
ATOM   8765  O O   . GLY D 1 114 ? 168.338 123.250 84.926  1.00 97.84  ? 79  GLY D O   1 
ATOM   8766  N N   . PRO D 1 115 ? 167.982 125.374 84.274  1.00 99.31  ? 80  PRO D N   1 
ATOM   8767  C CA  . PRO D 1 115 ? 169.103 125.872 85.088  1.00 96.70  ? 80  PRO D CA  1 
ATOM   8768  C C   . PRO D 1 115 ? 168.957 125.583 86.570  1.00 94.67  ? 80  PRO D C   1 
ATOM   8769  O O   . PRO D 1 115 ? 169.963 125.330 87.245  1.00 90.69  ? 80  PRO D O   1 
ATOM   8770  C CB  . PRO D 1 115 ? 169.098 127.382 84.807  1.00 90.34  ? 80  PRO D CB  1 
ATOM   8771  C CG  . PRO D 1 115 ? 168.348 127.538 83.523  1.00 87.18  ? 80  PRO D CG  1 
ATOM   8772  C CD  . PRO D 1 115 ? 167.327 126.446 83.507  1.00 95.14  ? 80  PRO D CD  1 
ATOM   8773  N N   . MET D 1 116 ? 167.738 125.612 87.096  1.00 94.22  ? 81  MET D N   1 
ATOM   8774  C CA  . MET D 1 116 ? 167.499 125.376 88.508  1.00 92.84  ? 81  MET D CA  1 
ATOM   8775  C C   . MET D 1 116 ? 167.151 123.911 88.753  1.00 90.21  ? 81  MET D C   1 
ATOM   8776  O O   . MET D 1 116 ? 166.834 123.154 87.833  1.00 91.06  ? 81  MET D O   1 
ATOM   8777  C CB  . MET D 1 116 ? 166.380 126.284 89.019  1.00 95.62  ? 81  MET D CB  1 
ATOM   8778  C CG  . MET D 1 116 ? 166.668 127.768 88.862  1.00 105.55 ? 81  MET D CG  1 
ATOM   8779  S SD  . MET D 1 116 ? 165.384 128.810 89.581  1.00 125.35 ? 81  MET D SD  1 
ATOM   8780  C CE  . MET D 1 116 ? 165.620 128.485 91.327  1.00 100.78 ? 81  MET D CE  1 
ATOM   8781  N N   . THR D 1 117 ? 167.214 123.512 90.022  1.00 89.00  ? 82  THR D N   1 
ATOM   8782  C CA  . THR D 1 117 ? 166.840 122.166 90.427  1.00 87.86  ? 82  THR D CA  1 
ATOM   8783  C C   . THR D 1 117 ? 165.589 122.127 91.291  1.00 81.71  ? 82  THR D C   1 
ATOM   8784  O O   . THR D 1 117 ? 165.060 121.037 91.533  1.00 75.83  ? 82  THR D O   1 
ATOM   8785  C CB  . THR D 1 117 ? 167.995 121.496 91.187  1.00 92.50  ? 82  THR D CB  1 
ATOM   8786  O OG1 . THR D 1 117 ? 168.373 122.313 92.301  1.00 92.74  ? 82  THR D OG1 1 
ATOM   8787  C CG2 . THR D 1 117 ? 169.196 121.306 90.274  1.00 87.18  ? 82  THR D CG2 1 
ATOM   8788  N N   . VAL D 1 118 ? 165.108 123.275 91.760  1.00 79.54  ? 83  VAL D N   1 
ATOM   8789  C CA  . VAL D 1 118 ? 163.932 123.355 92.618  1.00 70.90  ? 83  VAL D CA  1 
ATOM   8790  C C   . VAL D 1 118 ? 163.052 124.487 92.108  1.00 69.90  ? 83  VAL D C   1 
ATOM   8791  O O   . VAL D 1 118 ? 163.548 125.568 91.772  1.00 77.09  ? 83  VAL D O   1 
ATOM   8792  C CB  . VAL D 1 118 ? 164.307 123.580 94.099  1.00 66.04  ? 83  VAL D CB  1 
ATOM   8793  C CG1 . VAL D 1 118 ? 163.068 123.528 94.978  1.00 58.55  ? 83  VAL D CG1 1 
ATOM   8794  C CG2 . VAL D 1 118 ? 165.327 122.550 94.564  1.00 65.82  ? 83  VAL D CG2 1 
ATOM   8795  N N   . LEU D 1 119 ? 161.747 124.239 92.046  1.00 59.69  ? 84  LEU D N   1 
ATOM   8796  C CA  . LEU D 1 119 ? 160.783 125.231 91.596  1.00 54.38  ? 84  LEU D CA  1 
ATOM   8797  C C   . LEU D 1 119 ? 159.771 125.477 92.704  1.00 47.60  ? 84  LEU D C   1 
ATOM   8798  O O   . LEU D 1 119 ? 159.297 124.533 93.341  1.00 49.06  ? 84  LEU D O   1 
ATOM   8799  C CB  . LEU D 1 119 ? 160.048 124.766 90.334  1.00 57.72  ? 84  LEU D CB  1 
ATOM   8800  C CG  . LEU D 1 119 ? 160.830 124.635 89.027  1.00 71.07  ? 84  LEU D CG  1 
ATOM   8801  C CD1 . LEU D 1 119 ? 159.940 124.050 87.942  1.00 67.29  ? 84  LEU D CD1 1 
ATOM   8802  C CD2 . LEU D 1 119 ? 161.398 125.969 88.591  1.00 75.27  ? 84  LEU D CD2 1 
ATOM   8803  N N   . ARG D 1 120 ? 159.444 126.743 92.934  1.00 51.27  ? 85  ARG D N   1 
ATOM   8804  C CA  . ARG D 1 120 ? 158.390 127.113 93.868  1.00 53.75  ? 85  ARG D CA  1 
ATOM   8805  C C   . ARG D 1 120 ? 157.129 127.446 93.082  1.00 46.14  ? 85  ARG D C   1 
ATOM   8806  O O   . ARG D 1 120 ? 157.156 128.301 92.191  1.00 45.35  ? 85  ARG D O   1 
ATOM   8807  C CB  . ARG D 1 120 ? 158.830 128.291 94.734  1.00 60.65  ? 85  ARG D CB  1 
ATOM   8808  C CG  . ARG D 1 120 ? 159.996 127.952 95.645  1.00 63.31  ? 85  ARG D CG  1 
ATOM   8809  C CD  . ARG D 1 120 ? 160.573 129.182 96.316  1.00 66.84  ? 85  ARG D CD  1 
ATOM   8810  N NE  . ARG D 1 120 ? 161.732 128.848 97.136  1.00 69.08  ? 85  ARG D NE  1 
ATOM   8811  C CZ  . ARG D 1 120 ? 162.971 128.745 96.675  1.00 70.04  ? 85  ARG D CZ  1 
ATOM   8812  N NH1 . ARG D 1 120 ? 163.254 128.948 95.399  1.00 71.98  ? 85  ARG D NH1 1 
ATOM   8813  N NH2 . ARG D 1 120 ? 163.951 128.426 97.516  1.00 63.70  ? 85  ARG D NH2 1 
ATOM   8814  N N   . LEU D 1 121 ? 156.034 126.770 93.410  1.00 43.59  ? 86  LEU D N   1 
ATOM   8815  C CA  . LEU D 1 121 ? 154.768 126.950 92.714  1.00 48.45  ? 86  LEU D CA  1 
ATOM   8816  C C   . LEU D 1 121 ? 153.872 127.916 93.475  1.00 55.06  ? 86  LEU D C   1 
ATOM   8817  O O   . LEU D 1 121 ? 153.764 127.846 94.703  1.00 51.72  ? 86  LEU D O   1 
ATOM   8818  C CB  . LEU D 1 121 ? 154.050 125.614 92.512  1.00 50.70  ? 86  LEU D CB  1 
ATOM   8819  C CG  . LEU D 1 121 ? 154.704 124.560 91.613  1.00 50.10  ? 86  LEU D CG  1 
ATOM   8820  C CD1 . LEU D 1 121 ? 153.635 123.835 90.814  1.00 53.63  ? 86  LEU D CD1 1 
ATOM   8821  C CD2 . LEU D 1 121 ? 155.734 125.173 90.671  1.00 48.88  ? 86  LEU D CD2 1 
ATOM   8822  N N   . ASN D 1 122 ? 153.236 128.820 92.737  1.00 61.17  ? 87  ASN D N   1 
ATOM   8823  C CA  . ASN D 1 122 ? 152.285 129.747 93.324  1.00 60.04  ? 87  ASN D CA  1 
ATOM   8824  C C   . ASN D 1 122 ? 151.051 128.999 93.826  1.00 64.10  ? 87  ASN D C   1 
ATOM   8825  O O   . ASN D 1 122 ? 150.740 127.890 93.381  1.00 64.88  ? 87  ASN D O   1 
ATOM   8826  C CB  . ASN D 1 122 ? 151.881 130.807 92.296  1.00 54.94  ? 87  ASN D CB  1 
ATOM   8827  C CG  . ASN D 1 122 ? 150.987 131.878 92.880  1.00 59.90  ? 87  ASN D CG  1 
ATOM   8828  O OD1 . ASN D 1 122 ? 151.068 132.191 94.067  1.00 60.35  ? 87  ASN D OD1 1 
ATOM   8829  N ND2 . ASN D 1 122 ? 150.122 132.446 92.047  1.00 61.60  ? 87  ASN D ND2 1 
ATOM   8830  N N   . ASN D 1 123 ? 150.357 129.618 94.787  1.00 64.59  ? 88  ASN D N   1 
ATOM   8831  C CA  . ASN D 1 123 ? 149.144 129.024 95.348  1.00 60.86  ? 88  ASN D CA  1 
ATOM   8832  C C   . ASN D 1 123 ? 148.141 128.676 94.254  1.00 58.93  ? 88  ASN D C   1 
ATOM   8833  O O   . ASN D 1 123 ? 147.421 127.677 94.352  1.00 56.43  ? 88  ASN D O   1 
ATOM   8834  C CB  . ASN D 1 123 ? 148.520 129.975 96.370  1.00 59.72  ? 88  ASN D CB  1 
ATOM   8835  C CG  . ASN D 1 123 ? 148.236 131.348 95.791  1.00 68.35  ? 88  ASN D CG  1 
ATOM   8836  O OD1 . ASN D 1 123 ? 147.264 131.538 95.059  1.00 65.55  ? 88  ASN D OD1 1 
ATOM   8837  N ND2 . ASN D 1 123 ? 149.087 132.315 96.117  1.00 67.88  ? 88  ASN D ND2 1 
ATOM   8838  N N   . LEU D 1 124 ? 148.080 129.499 93.206  1.00 59.59  ? 89  LEU D N   1 
ATOM   8839  C CA  . LEU D 1 124 ? 147.239 129.192 92.054  1.00 59.73  ? 89  LEU D CA  1 
ATOM   8840  C C   . LEU D 1 124 ? 147.755 127.969 91.306  1.00 64.16  ? 89  LEU D C   1 
ATOM   8841  O O   . LEU D 1 124 ? 146.966 127.134 90.849  1.00 67.98  ? 89  LEU D O   1 
ATOM   8842  C CB  . LEU D 1 124 ? 147.173 130.401 91.121  1.00 61.11  ? 89  LEU D CB  1 
ATOM   8843  C CG  . LEU D 1 124 ? 146.249 130.306 89.906  1.00 65.67  ? 89  LEU D CG  1 
ATOM   8844  C CD1 . LEU D 1 124 ? 144.807 130.122 90.339  1.00 74.11  ? 89  LEU D CD1 1 
ATOM   8845  C CD2 . LEU D 1 124 ? 146.395 131.536 89.025  1.00 57.88  ? 89  LEU D CD2 1 
ATOM   8846  N N   . MET D 1 125 ? 149.077 127.854 91.163  1.00 66.73  ? 90  MET D N   1 
ATOM   8847  C CA  . MET D 1 125 ? 149.661 126.690 90.503  1.00 65.29  ? 90  MET D CA  1 
ATOM   8848  C C   . MET D 1 125 ? 149.428 125.413 91.300  1.00 61.67  ? 90  MET D C   1 
ATOM   8849  O O   . MET D 1 125 ? 149.174 124.352 90.717  1.00 59.89  ? 90  MET D O   1 
ATOM   8850  C CB  . MET D 1 125 ? 151.159 126.912 90.291  1.00 62.39  ? 90  MET D CB  1 
ATOM   8851  C CG  . MET D 1 125 ? 151.500 127.928 89.218  1.00 64.58  ? 90  MET D CG  1 
ATOM   8852  S SD  . MET D 1 125 ? 151.084 127.342 87.568  1.00 92.72  ? 90  MET D SD  1 
ATOM   8853  C CE  . MET D 1 125 ? 152.131 125.892 87.472  1.00 72.93  ? 90  MET D CE  1 
ATOM   8854  N N   . ALA D 1 126 ? 149.515 125.489 92.631  1.00 58.99  ? 91  ALA D N   1 
ATOM   8855  C CA  . ALA D 1 126 ? 149.344 124.293 93.450  1.00 57.89  ? 91  ALA D CA  1 
ATOM   8856  C C   . ALA D 1 126 ? 147.950 123.696 93.296  1.00 63.35  ? 91  ALA D C   1 
ATOM   8857  O O   . ALA D 1 126 ? 147.794 122.470 93.264  1.00 65.63  ? 91  ALA D O   1 
ATOM   8858  C CB  . ALA D 1 126 ? 149.624 124.620 94.917  1.00 51.19  ? 91  ALA D CB  1 
ATOM   8859  N N   . SER D 1 127 ? 146.923 124.541 93.202  1.00 65.12  ? 92  SER D N   1 
ATOM   8860  C CA  . SER D 1 127 ? 145.565 124.043 93.020  1.00 61.10  ? 92  SER D CA  1 
ATOM   8861  C C   . SER D 1 127 ? 145.318 123.470 91.631  1.00 58.80  ? 92  SER D C   1 
ATOM   8862  O O   . SER D 1 127 ? 144.264 122.864 91.413  1.00 58.60  ? 92  SER D O   1 
ATOM   8863  C CB  . SER D 1 127 ? 144.557 125.157 93.301  1.00 67.54  ? 92  SER D CB  1 
ATOM   8864  O OG  . SER D 1 127 ? 144.743 126.248 92.417  1.00 71.86  ? 92  SER D OG  1 
ATOM   8865  N N   . LYS D 1 128 ? 146.250 123.637 90.696  1.00 58.20  ? 93  LYS D N   1 
ATOM   8866  C CA  . LYS D 1 128 ? 146.072 123.131 89.342  1.00 58.61  ? 93  LYS D CA  1 
ATOM   8867  C C   . LYS D 1 128 ? 146.564 121.703 89.157  1.00 55.24  ? 93  LYS D C   1 
ATOM   8868  O O   . LYS D 1 128 ? 146.331 121.121 88.092  1.00 58.99  ? 93  LYS D O   1 
ATOM   8869  C CB  . LYS D 1 128 ? 146.785 124.043 88.338  1.00 67.86  ? 93  LYS D CB  1 
ATOM   8870  C CG  . LYS D 1 128 ? 146.089 125.372 88.104  1.00 68.35  ? 93  LYS D CG  1 
ATOM   8871  C CD  . LYS D 1 128 ? 144.835 125.186 87.265  1.00 77.24  ? 93  LYS D CD  1 
ATOM   8872  C CE  . LYS D 1 128 ? 144.277 126.518 86.796  1.00 83.57  ? 93  LYS D CE  1 
ATOM   8873  N NZ  . LYS D 1 128 ? 143.057 126.340 85.963  1.00 76.63  ? 93  LYS D NZ  1 
ATOM   8874  N N   . ILE D 1 129 ? 147.227 121.120 90.152  1.00 56.63  ? 94  ILE D N   1 
ATOM   8875  C CA  . ILE D 1 129 ? 147.780 119.780 90.001  1.00 57.45  ? 94  ILE D CA  1 
ATOM   8876  C C   . ILE D 1 129 ? 147.123 118.857 91.015  1.00 59.44  ? 94  ILE D C   1 
ATOM   8877  O O   . ILE D 1 129 ? 146.298 119.294 91.824  1.00 62.33  ? 94  ILE D O   1 
ATOM   8878  C CB  . ILE D 1 129 ? 149.310 119.769 90.163  1.00 54.40  ? 94  ILE D CB  1 
ATOM   8879  C CG1 . ILE D 1 129 ? 149.692 119.817 91.639  1.00 49.19  ? 94  ILE D CG1 1 
ATOM   8880  C CG2 . ILE D 1 129 ? 149.934 120.944 89.432  1.00 55.64  ? 94  ILE D CG2 1 
ATOM   8881  C CD1 . ILE D 1 129 ? 151.165 119.674 91.865  1.00 41.69  ? 94  ILE D CD1 1 
ATOM   8882  N N   . TRP D 1 130 ? 147.488 117.578 90.986  1.00 53.74  ? 95  TRP D N   1 
ATOM   8883  C CA  . TRP D 1 130 ? 146.912 116.603 91.898  1.00 49.31  ? 95  TRP D CA  1 
ATOM   8884  C C   . TRP D 1 130 ? 147.734 116.573 93.176  1.00 44.51  ? 95  TRP D C   1 
ATOM   8885  O O   . TRP D 1 130 ? 148.962 116.446 93.133  1.00 44.40  ? 95  TRP D O   1 
ATOM   8886  C CB  . TRP D 1 130 ? 146.865 115.209 91.269  1.00 46.24  ? 95  TRP D CB  1 
ATOM   8887  C CG  . TRP D 1 130 ? 146.268 114.158 92.175  1.00 41.15  ? 95  TRP D CG  1 
ATOM   8888  C CD1 . TRP D 1 130 ? 144.982 113.704 92.154  1.00 40.23  ? 95  TRP D CD1 1 
ATOM   8889  C CD2 . TRP D 1 130 ? 146.930 113.431 93.222  1.00 41.01  ? 95  TRP D CD2 1 
ATOM   8890  N NE1 . TRP D 1 130 ? 144.799 112.748 93.121  1.00 36.52  ? 95  TRP D NE1 1 
ATOM   8891  C CE2 . TRP D 1 130 ? 145.979 112.561 93.790  1.00 38.66  ? 95  TRP D CE2 1 
ATOM   8892  C CE3 . TRP D 1 130 ? 148.231 113.431 93.733  1.00 40.48  ? 95  TRP D CE3 1 
ATOM   8893  C CZ2 . TRP D 1 130 ? 146.287 111.702 94.844  1.00 35.97  ? 95  TRP D CZ2 1 
ATOM   8894  C CZ3 . TRP D 1 130 ? 148.533 112.578 94.780  1.00 38.22  ? 95  TRP D CZ3 1 
ATOM   8895  C CH2 . TRP D 1 130 ? 147.566 111.726 95.323  1.00 34.19  ? 95  TRP D CH2 1 
ATOM   8896  N N   . THR D 1 131 ? 147.056 116.697 94.304  1.00 40.06  ? 96  THR D N   1 
ATOM   8897  C CA  . THR D 1 131 ? 147.648 116.553 95.622  1.00 36.82  ? 96  THR D CA  1 
ATOM   8898  C C   . THR D 1 131 ? 146.815 115.555 96.406  1.00 37.45  ? 96  THR D C   1 
ATOM   8899  O O   . THR D 1 131 ? 145.630 115.362 96.111  1.00 41.54  ? 96  THR D O   1 
ATOM   8900  C CB  . THR D 1 131 ? 147.691 117.900 96.358  1.00 36.95  ? 96  THR D CB  1 
ATOM   8901  O OG1 . THR D 1 131 ? 146.372 118.455 96.413  1.00 45.00  ? 96  THR D OG1 1 
ATOM   8902  C CG2 . THR D 1 131 ? 148.610 118.870 95.635  1.00 35.77  ? 96  THR D CG2 1 
ATOM   8903  N N   . PRO D 1 132 ? 147.404 114.889 97.398  1.00 33.57  ? 97  PRO D N   1 
ATOM   8904  C CA  . PRO D 1 132 ? 146.629 113.928 98.188  1.00 31.01  ? 97  PRO D CA  1 
ATOM   8905  C C   . PRO D 1 132 ? 145.448 114.608 98.860  1.00 33.09  ? 97  PRO D C   1 
ATOM   8906  O O   . PRO D 1 132 ? 145.548 115.737 99.344  1.00 32.22  ? 97  PRO D O   1 
ATOM   8907  C CB  . PRO D 1 132 ? 147.641 113.401 99.210  1.00 28.62  ? 97  PRO D CB  1 
ATOM   8908  C CG  . PRO D 1 132 ? 148.969 113.702 98.628  1.00 31.72  ? 97  PRO D CG  1 
ATOM   8909  C CD  . PRO D 1 132 ? 148.805 114.956 97.841  1.00 34.16  ? 97  PRO D CD  1 
ATOM   8910  N N   . ASP D 1 133 ? 144.324 113.900 98.892  1.00 32.03  ? 98  ASP D N   1 
ATOM   8911  C CA  . ASP D 1 133 ? 143.124 114.396 99.560  1.00 30.88  ? 98  ASP D CA  1 
ATOM   8912  C C   . ASP D 1 133 ? 143.129 113.957 101.024 1.00 26.29  ? 98  ASP D C   1 
ATOM   8913  O O   . ASP D 1 133 ? 142.231 113.286 101.529 1.00 23.62  ? 98  ASP D O   1 
ATOM   8914  C CB  . ASP D 1 133 ? 141.878 113.924 98.819  1.00 34.97  ? 98  ASP D CB  1 
ATOM   8915  C CG  . ASP D 1 133 ? 141.735 112.419 98.816  1.00 34.59  ? 98  ASP D CG  1 
ATOM   8916  O OD1 . ASP D 1 133 ? 142.772 111.725 98.813  1.00 26.33  ? 98  ASP D OD1 1 
ATOM   8917  O OD2 . ASP D 1 133 ? 140.586 111.932 98.807  1.00 37.99  ? 98  ASP D OD2 1 
ATOM   8918  N N   . THR D 1 134 ? 144.185 114.384 101.710 1.00 24.58  ? 99  THR D N   1 
ATOM   8919  C CA  . THR D 1 134 ? 144.377 114.020 103.102 1.00 19.37  ? 99  THR D CA  1 
ATOM   8920  C C   . THR D 1 134 ? 143.394 114.782 103.976 1.00 17.48  ? 99  THR D C   1 
ATOM   8921  O O   . THR D 1 134 ? 143.104 115.957 103.739 1.00 25.86  ? 99  THR D O   1 
ATOM   8922  C CB  . THR D 1 134 ? 145.814 114.318 103.535 1.00 20.98  ? 99  THR D CB  1 
ATOM   8923  O OG1 . THR D 1 134 ? 146.726 113.624 102.676 1.00 23.12  ? 99  THR D OG1 1 
ATOM   8924  C CG2 . THR D 1 134 ? 146.054 113.877 104.969 1.00 15.91  ? 99  THR D CG2 1 
ATOM   8925  N N   . PHE D 1 135 ? 142.884 114.102 104.994 1.00 14.51  ? 100 PHE D N   1 
ATOM   8926  C CA  . PHE D 1 135 ? 141.976 114.705 105.952 1.00 14.01  ? 100 PHE D CA  1 
ATOM   8927  C C   . PHE D 1 135 ? 142.228 114.062 107.302 1.00 13.81  ? 100 PHE D C   1 
ATOM   8928  O O   . PHE D 1 135 ? 142.838 112.997 107.396 1.00 18.42  ? 100 PHE D O   1 
ATOM   8929  C CB  . PHE D 1 135 ? 140.511 114.535 105.530 1.00 16.54  ? 100 PHE D CB  1 
ATOM   8930  C CG  . PHE D 1 135 ? 139.927 113.196 105.888 1.00 16.88  ? 100 PHE D CG  1 
ATOM   8931  C CD1 . PHE D 1 135 ? 140.402 112.038 105.302 1.00 17.21  ? 100 PHE D CD1 1 
ATOM   8932  C CD2 . PHE D 1 135 ? 138.904 113.097 106.814 1.00 15.56  ? 100 PHE D CD2 1 
ATOM   8933  C CE1 . PHE D 1 135 ? 139.867 110.811 105.630 1.00 14.36  ? 100 PHE D CE1 1 
ATOM   8934  C CE2 . PHE D 1 135 ? 138.367 111.871 107.144 1.00 13.80  ? 100 PHE D CE2 1 
ATOM   8935  C CZ  . PHE D 1 135 ? 138.849 110.728 106.550 1.00 12.69  ? 100 PHE D CZ  1 
ATOM   8936  N N   . PHE D 1 136 ? 141.744 114.713 108.347 1.00 11.05  ? 101 PHE D N   1 
ATOM   8937  C CA  . PHE D 1 136 ? 141.939 114.241 109.707 1.00 11.40  ? 101 PHE D CA  1 
ATOM   8938  C C   . PHE D 1 136 ? 140.653 113.576 110.176 1.00 14.48  ? 101 PHE D C   1 
ATOM   8939  O O   . PHE D 1 136 ? 139.597 114.216 110.210 1.00 21.50  ? 101 PHE D O   1 
ATOM   8940  C CB  . PHE D 1 136 ? 142.342 115.394 110.626 1.00 12.19  ? 101 PHE D CB  1 
ATOM   8941  C CG  . PHE D 1 136 ? 143.651 116.032 110.249 1.00 15.62  ? 101 PHE D CG  1 
ATOM   8942  C CD1 . PHE D 1 136 ? 144.850 115.491 110.677 1.00 15.72  ? 101 PHE D CD1 1 
ATOM   8943  C CD2 . PHE D 1 136 ? 143.683 117.164 109.454 1.00 14.69  ? 101 PHE D CD2 1 
ATOM   8944  C CE1 . PHE D 1 136 ? 146.053 116.071 110.325 1.00 11.75  ? 101 PHE D CE1 1 
ATOM   8945  C CE2 . PHE D 1 136 ? 144.885 117.748 109.100 1.00 11.37  ? 101 PHE D CE2 1 
ATOM   8946  C CZ  . PHE D 1 136 ? 146.069 117.200 109.536 1.00 10.12  ? 101 PHE D CZ  1 
ATOM   8947  N N   . HIS D 1 137 ? 140.744 112.288 110.519 1.00 13.75  ? 102 HIS D N   1 
ATOM   8948  C CA  . HIS D 1 137 ? 139.547 111.509 110.816 1.00 13.25  ? 102 HIS D CA  1 
ATOM   8949  C C   . HIS D 1 137 ? 138.810 112.075 112.020 1.00 18.02  ? 102 HIS D C   1 
ATOM   8950  O O   . HIS D 1 137 ? 137.576 112.155 112.022 1.00 24.26  ? 102 HIS D O   1 
ATOM   8951  C CB  . HIS D 1 137 ? 139.908 110.042 111.063 1.00 13.67  ? 102 HIS D CB  1 
ATOM   8952  C CG  . HIS D 1 137 ? 140.578 109.368 109.906 1.00 16.49  ? 102 HIS D CG  1 
ATOM   8953  N ND1 . HIS D 1 137 ? 140.733 108.001 109.836 1.00 15.28  ? 102 HIS D ND1 1 
ATOM   8954  C CD2 . HIS D 1 137 ? 141.129 109.866 108.774 1.00 18.38  ? 102 HIS D CD2 1 
ATOM   8955  C CE1 . HIS D 1 137 ? 141.351 107.686 108.712 1.00 16.30  ? 102 HIS D CE1 1 
ATOM   8956  N NE2 . HIS D 1 137 ? 141.602 108.800 108.049 1.00 18.39  ? 102 HIS D NE2 1 
ATOM   8957  N N   . ASN D 1 138 ? 139.546 112.464 113.053 1.00 16.24  ? 103 ASN D N   1 
ATOM   8958  C CA  . ASN D 1 138 ? 138.958 113.001 114.269 1.00 17.47  ? 103 ASN D CA  1 
ATOM   8959  C C   . ASN D 1 138 ? 138.899 114.523 114.279 1.00 19.24  ? 103 ASN D C   1 
ATOM   8960  O O   . ASN D 1 138 ? 138.641 115.108 115.333 1.00 24.84  ? 103 ASN D O   1 
ATOM   8961  C CB  . ASN D 1 138 ? 139.733 112.505 115.490 1.00 17.62  ? 103 ASN D CB  1 
ATOM   8962  C CG  . ASN D 1 138 ? 141.207 112.820 115.407 1.00 18.47  ? 103 ASN D CG  1 
ATOM   8963  O OD1 . ASN D 1 138 ? 141.789 112.824 114.325 1.00 22.24  ? 103 ASN D OD1 1 
ATOM   8964  N ND2 . ASN D 1 138 ? 141.823 113.078 116.553 1.00 18.00  ? 103 ASN D ND2 1 
ATOM   8965  N N   . GLY D 1 139 ? 139.164 115.181 113.153 1.00 17.16  ? 104 GLY D N   1 
ATOM   8966  C CA  . GLY D 1 139 ? 139.045 116.629 113.117 1.00 18.44  ? 104 GLY D CA  1 
ATOM   8967  C C   . GLY D 1 139 ? 137.607 117.081 113.316 1.00 22.18  ? 104 GLY D C   1 
ATOM   8968  O O   . GLY D 1 139 ? 136.661 116.446 112.848 1.00 26.73  ? 104 GLY D O   1 
ATOM   8969  N N   . LYS D 1 140 ? 137.449 118.206 114.016 1.00 21.31  ? 105 LYS D N   1 
ATOM   8970  C CA  . LYS D 1 140 ? 136.149 118.829 114.242 1.00 20.63  ? 105 LYS D CA  1 
ATOM   8971  C C   . LYS D 1 140 ? 135.938 120.078 113.403 1.00 23.02  ? 105 LYS D C   1 
ATOM   8972  O O   . LYS D 1 140 ? 134.873 120.255 112.808 1.00 30.97  ? 105 LYS D O   1 
ATOM   8973  C CB  . LYS D 1 140 ? 135.974 119.177 115.725 1.00 21.55  ? 105 LYS D CB  1 
ATOM   8974  C CG  . LYS D 1 140 ? 135.928 117.979 116.637 1.00 23.60  ? 105 LYS D CG  1 
ATOM   8975  C CD  . LYS D 1 140 ? 135.783 118.399 118.084 1.00 28.60  ? 105 LYS D CD  1 
ATOM   8976  C CE  . LYS D 1 140 ? 134.413 118.989 118.352 1.00 32.03  ? 105 LYS D CE  1 
ATOM   8977  N NZ  . LYS D 1 140 ? 134.220 119.292 119.795 1.00 36.62  ? 105 LYS D NZ  1 
ATOM   8978  N N   . LYS D 1 141 ? 136.926 120.967 113.369 1.00 22.00  ? 106 LYS D N   1 
ATOM   8979  C CA  . LYS D 1 141 ? 136.866 122.156 112.526 1.00 26.28  ? 106 LYS D CA  1 
ATOM   8980  C C   . LYS D 1 141 ? 138.293 122.660 112.379 1.00 29.34  ? 106 LYS D C   1 
ATOM   8981  O O   . LYS D 1 141 ? 138.895 123.104 113.361 1.00 29.99  ? 106 LYS D O   1 
ATOM   8982  C CB  . LYS D 1 141 ? 135.967 123.217 113.150 1.00 27.72  ? 106 LYS D CB  1 
ATOM   8983  C CG  . LYS D 1 141 ? 135.766 124.465 112.306 1.00 31.01  ? 106 LYS D CG  1 
ATOM   8984  C CD  . LYS D 1 141 ? 134.958 124.179 111.057 1.00 31.13  ? 106 LYS D CD  1 
ATOM   8985  C CE  . LYS D 1 141 ? 134.747 125.445 110.244 1.00 30.66  ? 106 LYS D CE  1 
ATOM   8986  N NZ  . LYS D 1 141 ? 134.055 125.172 108.956 1.00 37.19  ? 106 LYS D NZ  1 
ATOM   8987  N N   . SER D 1 142 ? 138.822 122.602 111.165 1.00 26.63  ? 107 SER D N   1 
ATOM   8988  C CA  . SER D 1 142 ? 140.217 122.920 110.919 1.00 25.02  ? 107 SER D CA  1 
ATOM   8989  C C   . SER D 1 142 ? 140.310 124.143 110.021 1.00 27.73  ? 107 SER D C   1 
ATOM   8990  O O   . SER D 1 142 ? 139.436 124.387 109.183 1.00 28.98  ? 107 SER D O   1 
ATOM   8991  C CB  . SER D 1 142 ? 140.951 121.736 110.288 1.00 23.06  ? 107 SER D CB  1 
ATOM   8992  O OG  . SER D 1 142 ? 140.945 120.615 111.153 1.00 28.51  ? 107 SER D OG  1 
ATOM   8993  N N   . VAL D 1 143 ? 141.378 124.912 110.201 1.00 26.58  ? 108 VAL D N   1 
ATOM   8994  C CA  . VAL D 1 143 ? 141.570 126.168 109.491 1.00 26.08  ? 108 VAL D CA  1 
ATOM   8995  C C   . VAL D 1 143 ? 142.887 126.088 108.739 1.00 24.29  ? 108 VAL D C   1 
ATOM   8996  O O   . VAL D 1 143 ? 143.932 125.809 109.337 1.00 24.95  ? 108 VAL D O   1 
ATOM   8997  C CB  . VAL D 1 143 ? 141.564 127.372 110.450 1.00 28.23  ? 108 VAL D CB  1 
ATOM   8998  C CG1 . VAL D 1 143 ? 141.813 128.658 109.684 1.00 29.62  ? 108 VAL D CG1 1 
ATOM   8999  C CG2 . VAL D 1 143 ? 140.250 127.445 111.209 1.00 31.68  ? 108 VAL D CG2 1 
ATOM   9000  N N   . ALA D 1 144 ? 142.839 126.325 107.433 1.00 26.48  ? 109 ALA D N   1 
ATOM   9001  C CA  . ALA D 1 144 ? 144.040 126.517 106.632 1.00 30.55  ? 109 ALA D CA  1 
ATOM   9002  C C   . ALA D 1 144 ? 144.244 128.019 106.502 1.00 35.98  ? 109 ALA D C   1 
ATOM   9003  O O   . ALA D 1 144 ? 143.487 128.695 105.798 1.00 38.99  ? 109 ALA D O   1 
ATOM   9004  C CB  . ALA D 1 144 ? 143.909 125.847 105.267 1.00 28.63  ? 109 ALA D CB  1 
ATOM   9005  N N   . HIS D 1 145 ? 145.259 128.539 107.188 1.00 31.48  ? 110 HIS D N   1 
ATOM   9006  C CA  . HIS D 1 145 ? 145.405 129.981 107.319 1.00 33.35  ? 110 HIS D CA  1 
ATOM   9007  C C   . HIS D 1 145 ? 145.637 130.621 105.956 1.00 36.89  ? 110 HIS D C   1 
ATOM   9008  O O   . HIS D 1 145 ? 146.316 130.057 105.095 1.00 36.12  ? 110 HIS D O   1 
ATOM   9009  C CB  . HIS D 1 145 ? 146.561 130.298 108.260 1.00 29.24  ? 110 HIS D CB  1 
ATOM   9010  C CG  . HIS D 1 145 ? 146.367 129.768 109.645 1.00 25.96  ? 110 HIS D CG  1 
ATOM   9011  N ND1 . HIS D 1 145 ? 145.839 130.525 110.667 1.00 31.46  ? 110 HIS D ND1 1 
ATOM   9012  C CD2 . HIS D 1 145 ? 146.635 128.553 110.176 1.00 21.28  ? 110 HIS D CD2 1 
ATOM   9013  C CE1 . HIS D 1 145 ? 145.789 129.798 111.769 1.00 25.57  ? 110 HIS D CE1 1 
ATOM   9014  N NE2 . HIS D 1 145 ? 146.268 128.598 111.498 1.00 20.09  ? 110 HIS D NE2 1 
ATOM   9015  N N   . ASN D 1 146 ? 145.062 131.808 105.758 1.00 36.31  ? 111 ASN D N   1 
ATOM   9016  C CA  . ASN D 1 146 ? 145.100 132.448 104.450 1.00 38.66  ? 111 ASN D CA  1 
ATOM   9017  C C   . ASN D 1 146 ? 145.485 133.919 104.585 1.00 39.51  ? 111 ASN D C   1 
ATOM   9018  O O   . ASN D 1 146 ? 145.081 134.755 103.773 1.00 44.25  ? 111 ASN D O   1 
ATOM   9019  C CB  . ASN D 1 146 ? 143.759 132.259 103.734 1.00 47.51  ? 111 ASN D CB  1 
ATOM   9020  C CG  . ASN D 1 146 ? 143.924 132.053 102.242 1.00 54.15  ? 111 ASN D CG  1 
ATOM   9021  O OD1 . ASN D 1 146 ? 144.700 131.196 101.835 1.00 55.41  ? 111 ASN D OD1 1 
ATOM   9022  N ND2 . ASN D 1 146 ? 143.170 132.776 101.420 1.00 55.88  ? 111 ASN D ND2 1 
ATOM   9023  N N   . MET D 1 147 ? 146.267 134.238 105.619 1.00 38.96  ? 112 MET D N   1 
ATOM   9024  C CA  . MET D 1 147 ? 146.686 135.595 105.951 1.00 37.58  ? 112 MET D CA  1 
ATOM   9025  C C   . MET D 1 147 ? 148.203 135.662 106.055 1.00 31.29  ? 112 MET D C   1 
ATOM   9026  O O   . MET D 1 147 ? 148.803 134.866 106.783 1.00 30.76  ? 112 MET D O   1 
ATOM   9027  C CB  . MET D 1 147 ? 146.057 136.049 107.269 1.00 39.83  ? 112 MET D CB  1 
ATOM   9028  C CG  . MET D 1 147 ? 146.372 137.479 107.660 1.00 36.43  ? 112 MET D CG  1 
ATOM   9029  S SD  . MET D 1 147 ? 145.548 138.624 106.547 1.00 57.08  ? 112 MET D SD  1 
ATOM   9030  C CE  . MET D 1 147 ? 143.881 137.985 106.639 1.00 47.59  ? 112 MET D CE  1 
ATOM   9031  N N   . THR D 1 148 ? 148.829 136.606 105.350 1.00 30.81  ? 113 THR D N   1 
ATOM   9032  C CA  . THR D 1 148 ? 148.175 137.525 104.423 1.00 33.93  ? 113 THR D CA  1 
ATOM   9033  C C   . THR D 1 148 ? 147.869 136.833 103.105 1.00 36.56  ? 113 THR D C   1 
ATOM   9034  O O   . THR D 1 148 ? 146.882 137.139 102.436 1.00 38.58  ? 113 THR D O   1 
ATOM   9035  C CB  . THR D 1 148 ? 149.043 138.767 104.153 1.00 27.29  ? 113 THR D CB  1 
ATOM   9036  O OG1 . THR D 1 148 ? 150.277 138.366 103.547 1.00 25.65  ? 113 THR D OG1 1 
ATOM   9037  C CG2 . THR D 1 148 ? 149.346 139.492 105.449 1.00 24.15  ? 113 THR D CG2 1 
ATOM   9038  N N   . MET D 1 149 ? 148.734 135.901 102.743 1.00 34.71  ? 114 MET D N   1 
ATOM   9039  C CA  . MET D 1 149 ? 148.568 135.031 101.597 1.00 37.23  ? 114 MET D CA  1 
ATOM   9040  C C   . MET D 1 149 ? 148.265 133.618 102.075 1.00 38.27  ? 114 MET D C   1 
ATOM   9041  O O   . MET D 1 149 ? 148.315 133.335 103.276 1.00 37.09  ? 114 MET D O   1 
ATOM   9042  C CB  . MET D 1 149 ? 149.846 135.050 100.748 1.00 39.80  ? 114 MET D CB  1 
ATOM   9043  C CG  . MET D 1 149 ? 150.151 136.395 100.109 1.00 47.98  ? 114 MET D CG  1 
ATOM   9044  S SD  . MET D 1 149 ? 148.916 136.909 98.902  1.00 77.45  ? 114 MET D SD  1 
ATOM   9045  C CE  . MET D 1 149 ? 149.208 135.723 97.591  1.00 63.61  ? 114 MET D CE  1 
ATOM   9046  N N   . PRO D 1 150 ? 147.918 132.704 101.168 1.00 40.52  ? 115 PRO D N   1 
ATOM   9047  C CA  . PRO D 1 150 ? 147.780 131.300 101.575 1.00 38.75  ? 115 PRO D CA  1 
ATOM   9048  C C   . PRO D 1 150 ? 149.070 130.758 102.171 1.00 36.12  ? 115 PRO D C   1 
ATOM   9049  O O   . PRO D 1 150 ? 150.146 130.884 101.583 1.00 38.36  ? 115 PRO D O   1 
ATOM   9050  C CB  . PRO D 1 150 ? 147.409 130.585 100.271 1.00 39.44  ? 115 PRO D CB  1 
ATOM   9051  C CG  . PRO D 1 150 ? 146.805 131.635 99.425  1.00 44.09  ? 115 PRO D CG  1 
ATOM   9052  C CD  . PRO D 1 150 ? 147.514 132.905 99.764  1.00 44.38  ? 115 PRO D CD  1 
ATOM   9053  N N   . ASN D 1 151 ? 148.956 130.151 103.349 1.00 28.23  ? 116 ASN D N   1 
ATOM   9054  C CA  . ASN D 1 151 ? 150.121 129.590 104.031 1.00 23.25  ? 116 ASN D CA  1 
ATOM   9055  C C   . ASN D 1 151 ? 150.365 128.163 103.541 1.00 22.56  ? 116 ASN D C   1 
ATOM   9056  O O   . ASN D 1 151 ? 150.293 127.185 104.281 1.00 23.02  ? 116 ASN D O   1 
ATOM   9057  C CB  . ASN D 1 151 ? 149.952 129.649 105.544 1.00 21.84  ? 116 ASN D CB  1 
ATOM   9058  C CG  . ASN D 1 151 ? 149.771 131.063 106.056 1.00 26.51  ? 116 ASN D CG  1 
ATOM   9059  O OD1 . ASN D 1 151 ? 149.279 131.276 107.161 1.00 24.39  ? 116 ASN D OD1 1 
ATOM   9060  N ND2 . ASN D 1 151 ? 150.182 132.039 105.257 1.00 34.24  ? 116 ASN D ND2 1 
ATOM   9061  N N   . LYS D 1 152 ? 150.650 128.072 102.246 1.00 23.25  ? 117 LYS D N   1 
ATOM   9062  C CA  . LYS D 1 152 ? 150.998 126.827 101.583 1.00 19.77  ? 117 LYS D CA  1 
ATOM   9063  C C   . LYS D 1 152 ? 152.308 127.022 100.836 1.00 21.87  ? 117 LYS D C   1 
ATOM   9064  O O   . LYS D 1 152 ? 152.776 128.146 100.636 1.00 28.75  ? 117 LYS D O   1 
ATOM   9065  C CB  . LYS D 1 152 ? 149.899 126.378 100.611 1.00 21.51  ? 117 LYS D CB  1 
ATOM   9066  C CG  . LYS D 1 152 ? 148.541 126.175 101.253 1.00 25.11  ? 117 LYS D CG  1 
ATOM   9067  C CD  . LYS D 1 152 ? 147.496 125.806 100.216 1.00 28.77  ? 117 LYS D CD  1 
ATOM   9068  C CE  . LYS D 1 152 ? 146.175 125.445 100.870 1.00 34.86  ? 117 LYS D CE  1 
ATOM   9069  N NZ  . LYS D 1 152 ? 145.133 125.101 99.866  1.00 41.97  ? 117 LYS D NZ  1 
ATOM   9070  N N   . LEU D 1 153 ? 152.894 125.909 100.406 1.00 21.70  ? 118 LEU D N   1 
ATOM   9071  C CA  . LEU D 1 153 ? 154.113 125.951 99.612  1.00 23.10  ? 118 LEU D CA  1 
ATOM   9072  C C   . LEU D 1 153 ? 154.270 124.618 98.904  1.00 22.18  ? 118 LEU D C   1 
ATOM   9073  O O   . LEU D 1 153 ? 154.237 123.566 99.547  1.00 21.22  ? 118 LEU D O   1 
ATOM   9074  C CB  . LEU D 1 153 ? 155.337 126.238 100.484 1.00 26.85  ? 118 LEU D CB  1 
ATOM   9075  C CG  . LEU D 1 153 ? 156.679 126.249 99.754  1.00 37.01  ? 118 LEU D CG  1 
ATOM   9076  C CD1 . LEU D 1 153 ? 156.653 127.231 98.591  1.00 38.42  ? 118 LEU D CD1 1 
ATOM   9077  C CD2 . LEU D 1 153 ? 157.807 126.574 100.716 1.00 38.87  ? 118 LEU D CD2 1 
ATOM   9078  N N   . LEU D 1 154 ? 154.442 124.669 97.589  1.00 27.90  ? 119 LEU D N   1 
ATOM   9079  C CA  . LEU D 1 154 ? 154.631 123.481 96.770  1.00 32.22  ? 119 LEU D CA  1 
ATOM   9080  C C   . LEU D 1 154 ? 155.948 123.613 96.024  1.00 36.50  ? 119 LEU D C   1 
ATOM   9081  O O   . LEU D 1 154 ? 156.105 124.506 95.184  1.00 46.26  ? 119 LEU D O   1 
ATOM   9082  C CB  . LEU D 1 154 ? 153.468 123.311 95.795  1.00 32.37  ? 119 LEU D CB  1 
ATOM   9083  C CG  . LEU D 1 154 ? 153.522 122.111 94.858  1.00 34.45  ? 119 LEU D CG  1 
ATOM   9084  C CD1 . LEU D 1 154 ? 153.396 120.819 95.641  1.00 36.17  ? 119 LEU D CD1 1 
ATOM   9085  C CD2 . LEU D 1 154 ? 152.412 122.238 93.847  1.00 44.59  ? 119 LEU D CD2 1 
ATOM   9086  N N   . ARG D 1 155 ? 156.890 122.730 96.333  1.00 29.34  ? 120 ARG D N   1 
ATOM   9087  C CA  . ARG D 1 155 ? 158.191 122.703 95.688  1.00 32.59  ? 120 ARG D CA  1 
ATOM   9088  C C   . ARG D 1 155 ? 158.334 121.431 94.865  1.00 34.21  ? 120 ARG D C   1 
ATOM   9089  O O   . ARG D 1 155 ? 157.960 120.345 95.318  1.00 39.61  ? 120 ARG D O   1 
ATOM   9090  C CB  . ARG D 1 155 ? 159.302 122.780 96.735  1.00 39.24  ? 120 ARG D CB  1 
ATOM   9091  C CG  . ARG D 1 155 ? 159.420 124.146 97.384  1.00 47.52  ? 120 ARG D CG  1 
ATOM   9092  C CD  . ARG D 1 155 ? 160.480 124.163 98.468  1.00 51.74  ? 120 ARG D CD  1 
ATOM   9093  N NE  . ARG D 1 155 ? 160.559 125.467 99.114  1.00 53.00  ? 120 ARG D NE  1 
ATOM   9094  C CZ  . ARG D 1 155 ? 161.287 125.726 100.191 1.00 50.81  ? 120 ARG D CZ  1 
ATOM   9095  N NH1 . ARG D 1 155 ? 162.017 124.790 100.773 1.00 53.45  ? 120 ARG D NH1 1 
ATOM   9096  N NH2 . ARG D 1 155 ? 161.278 126.955 100.699 1.00 45.91  ? 120 ARG D NH2 1 
ATOM   9097  N N   . ILE D 1 156 ? 158.871 121.564 93.657  1.00 37.72  ? 121 ILE D N   1 
ATOM   9098  C CA  . ILE D 1 156 ? 159.065 120.437 92.754  1.00 39.04  ? 121 ILE D CA  1 
ATOM   9099  C C   . ILE D 1 156 ? 160.553 120.310 92.463  1.00 47.27  ? 121 ILE D C   1 
ATOM   9100  O O   . ILE D 1 156 ? 161.202 121.293 92.088  1.00 52.75  ? 121 ILE D O   1 
ATOM   9101  C CB  . ILE D 1 156 ? 158.268 120.606 91.448  1.00 41.41  ? 121 ILE D CB  1 
ATOM   9102  C CG1 . ILE D 1 156 ? 156.806 120.929 91.751  1.00 35.57  ? 121 ILE D CG1 1 
ATOM   9103  C CG2 . ILE D 1 156 ? 158.376 119.356 90.592  1.00 48.85  ? 121 ILE D CG2 1 
ATOM   9104  C CD1 . ILE D 1 156 ? 155.942 121.028 90.516  1.00 42.82  ? 121 ILE D CD1 1 
ATOM   9105  N N   . THR D 1 157 ? 161.084 119.104 92.620  1.00 49.98  ? 122 THR D N   1 
ATOM   9106  C CA  . THR D 1 157 ? 162.456 118.805 92.245  1.00 58.50  ? 122 THR D CA  1 
ATOM   9107  C C   . THR D 1 157 ? 162.474 118.213 90.841  1.00 61.48  ? 122 THR D C   1 
ATOM   9108  O O   . THR D 1 157 ? 161.483 117.640 90.382  1.00 59.62  ? 122 THR D O   1 
ATOM   9109  C CB  . THR D 1 157 ? 163.081 117.832 93.251  1.00 60.27  ? 122 THR D CB  1 
ATOM   9110  O OG1 . THR D 1 157 ? 162.923 118.355 94.576  1.00 63.39  ? 122 THR D OG1 1 
ATOM   9111  C CG2 . THR D 1 157 ? 164.566 117.643 92.988  1.00 66.78  ? 122 THR D CG2 1 
ATOM   9112  N N   . GLU D 1 158 ? 163.610 118.372 90.152  1.00 69.61  ? 123 GLU D N   1 
ATOM   9113  C CA  . GLU D 1 158 ? 163.721 117.879 88.782  1.00 70.40  ? 123 GLU D CA  1 
ATOM   9114  C C   . GLU D 1 158 ? 163.458 116.380 88.697  1.00 66.50  ? 123 GLU D C   1 
ATOM   9115  O O   . GLU D 1 158 ? 163.027 115.884 87.650  1.00 65.07  ? 123 GLU D O   1 
ATOM   9116  C CB  . GLU D 1 158 ? 165.100 118.212 88.213  1.00 70.27  ? 123 GLU D CB  1 
ATOM   9117  C CG  . GLU D 1 158 ? 166.258 117.592 88.973  1.00 72.51  ? 123 GLU D CG  1 
ATOM   9118  C CD  . GLU D 1 158 ? 167.604 118.097 88.492  1.00 87.12  ? 123 GLU D CD  1 
ATOM   9119  O OE1 . GLU D 1 158 ? 167.633 119.098 87.746  1.00 90.87  ? 123 GLU D OE1 1 
ATOM   9120  O OE2 . GLU D 1 158 ? 168.633 117.492 88.859  1.00 91.50  ? 123 GLU D OE2 1 
ATOM   9121  N N   . ASP D 1 159 ? 163.718 115.645 89.781  1.00 64.77  ? 124 ASP D N   1 
ATOM   9122  C CA  . ASP D 1 159 ? 163.456 114.211 89.809  1.00 59.46  ? 124 ASP D CA  1 
ATOM   9123  C C   . ASP D 1 159 ? 161.966 113.904 89.706  1.00 54.27  ? 124 ASP D C   1 
ATOM   9124  O O   . ASP D 1 159 ? 161.595 112.776 89.365  1.00 49.11  ? 124 ASP D O   1 
ATOM   9125  C CB  . ASP D 1 159 ? 164.041 113.618 91.095  1.00 57.53  ? 124 ASP D CB  1 
ATOM   9126  C CG  . ASP D 1 159 ? 164.045 112.097 91.106  1.00 58.49  ? 124 ASP D CG  1 
ATOM   9127  O OD1 . ASP D 1 159 ? 163.752 111.474 90.065  1.00 58.35  ? 124 ASP D OD1 1 
ATOM   9128  O OD2 . ASP D 1 159 ? 164.346 111.520 92.172  1.00 62.07  ? 124 ASP D OD2 1 
ATOM   9129  N N   . GLY D 1 160 ? 161.107 114.888 89.961  1.00 58.75  ? 125 GLY D N   1 
ATOM   9130  C CA  . GLY D 1 160 ? 159.678 114.675 90.021  1.00 55.64  ? 125 GLY D CA  1 
ATOM   9131  C C   . GLY D 1 160 ? 159.111 114.570 91.419  1.00 45.84  ? 125 GLY D C   1 
ATOM   9132  O O   . GLY D 1 160 ? 157.907 114.328 91.563  1.00 44.72  ? 125 GLY D O   1 
ATOM   9133  N N   . THR D 1 161 ? 159.935 114.740 92.449  1.00 43.53  ? 126 THR D N   1 
ATOM   9134  C CA  . THR D 1 161 ? 159.464 114.680 93.824  1.00 37.84  ? 126 THR D CA  1 
ATOM   9135  C C   . THR D 1 161 ? 158.881 116.027 94.227  1.00 36.70  ? 126 THR D C   1 
ATOM   9136  O O   . THR D 1 161 ? 159.463 117.078 93.950  1.00 43.18  ? 126 THR D O   1 
ATOM   9137  C CB  . THR D 1 161 ? 160.607 114.295 94.764  1.00 42.74  ? 126 THR D CB  1 
ATOM   9138  O OG1 . THR D 1 161 ? 161.012 112.947 94.498  1.00 47.00  ? 126 THR D OG1 1 
ATOM   9139  C CG2 . THR D 1 161 ? 160.172 114.404 96.220  1.00 35.71  ? 126 THR D CG2 1 
ATOM   9140  N N   . LEU D 1 162 ? 157.728 115.994 94.887  1.00 31.49  ? 127 LEU D N   1 
ATOM   9141  C CA  . LEU D 1 162 ? 157.038 117.200 95.319  1.00 30.31  ? 127 LEU D CA  1 
ATOM   9142  C C   . LEU D 1 162 ? 157.015 117.266 96.838  1.00 29.06  ? 127 LEU D C   1 
ATOM   9143  O O   . LEU D 1 162 ? 156.599 116.310 97.499  1.00 33.16  ? 127 LEU D O   1 
ATOM   9144  C CB  . LEU D 1 162 ? 155.604 117.247 94.785  1.00 23.87  ? 127 LEU D CB  1 
ATOM   9145  C CG  . LEU D 1 162 ? 155.363 117.115 93.281  1.00 31.27  ? 127 LEU D CG  1 
ATOM   9146  C CD1 . LEU D 1 162 ? 155.239 115.658 92.873  1.00 37.06  ? 127 LEU D CD1 1 
ATOM   9147  C CD2 . LEU D 1 162 ? 154.124 117.886 92.881  1.00 30.11  ? 127 LEU D CD2 1 
ATOM   9148  N N   . LEU D 1 163 ? 157.465 118.390 97.384  1.00 27.70  ? 128 LEU D N   1 
ATOM   9149  C CA  . LEU D 1 163 ? 157.335 118.687 98.803  1.00 23.76  ? 128 LEU D CA  1 
ATOM   9150  C C   . LEU D 1 163 ? 156.249 119.740 98.944  1.00 25.95  ? 128 LEU D C   1 
ATOM   9151  O O   . LEU D 1 163 ? 156.333 120.806 98.326  1.00 35.34  ? 128 LEU D O   1 
ATOM   9152  C CB  . LEU D 1 163 ? 158.656 119.180 99.392  1.00 26.77  ? 128 LEU D CB  1 
ATOM   9153  C CG  . LEU D 1 163 ? 158.632 119.616 100.859 1.00 26.24  ? 128 LEU D CG  1 
ATOM   9154  C CD1 . LEU D 1 163 ? 158.107 118.501 101.744 1.00 26.45  ? 128 LEU D CD1 1 
ATOM   9155  C CD2 . LEU D 1 163 ? 160.014 120.055 101.312 1.00 33.41  ? 128 LEU D CD2 1 
ATOM   9156  N N   . TYR D 1 164 ? 155.238 119.445 99.754  1.00 22.06  ? 129 TYR D N   1 
ATOM   9157  C CA  . TYR D 1 164 ? 154.032 120.261 99.830  1.00 21.69  ? 129 TYR D CA  1 
ATOM   9158  C C   . TYR D 1 164 ? 153.751 120.511 101.303 1.00 18.02  ? 129 TYR D C   1 
ATOM   9159  O O   . TYR D 1 164 ? 153.348 119.595 102.026 1.00 21.83  ? 129 TYR D O   1 
ATOM   9160  C CB  . TYR D 1 164 ? 152.861 119.562 99.136  1.00 23.09  ? 129 TYR D CB  1 
ATOM   9161  C CG  . TYR D 1 164 ? 151.583 120.363 99.070  1.00 23.60  ? 129 TYR D CG  1 
ATOM   9162  C CD1 . TYR D 1 164 ? 151.604 121.706 98.726  1.00 27.40  ? 129 TYR D CD1 1 
ATOM   9163  C CD2 . TYR D 1 164 ? 150.353 119.765 99.298  1.00 25.04  ? 129 TYR D CD2 1 
ATOM   9164  C CE1 . TYR D 1 164 ? 150.439 122.440 98.645  1.00 32.54  ? 129 TYR D CE1 1 
ATOM   9165  C CE2 . TYR D 1 164 ? 149.182 120.490 99.215  1.00 28.87  ? 129 TYR D CE2 1 
ATOM   9166  C CZ  . TYR D 1 164 ? 149.231 121.828 98.890  1.00 33.54  ? 129 TYR D CZ  1 
ATOM   9167  O OH  . TYR D 1 164 ? 148.069 122.558 98.806  1.00 34.89  ? 129 TYR D OH  1 
ATOM   9168  N N   . THR D 1 165 ? 153.958 121.746 101.747 1.00 16.20  ? 130 THR D N   1 
ATOM   9169  C CA  . THR D 1 165 ? 153.777 122.116 103.140 1.00 15.97  ? 130 THR D CA  1 
ATOM   9170  C C   . THR D 1 165 ? 152.650 123.128 103.274 1.00 18.27  ? 130 THR D C   1 
ATOM   9171  O O   . THR D 1 165 ? 152.438 123.970 102.396 1.00 26.49  ? 130 THR D O   1 
ATOM   9172  C CB  . THR D 1 165 ? 155.070 122.706 103.716 1.00 17.95  ? 130 THR D CB  1 
ATOM   9173  O OG1 . THR D 1 165 ? 156.172 121.855 103.380 1.00 24.99  ? 130 THR D OG1 1 
ATOM   9174  C CG2 . THR D 1 165 ? 154.984 122.836 105.229 1.00 19.08  ? 130 THR D CG2 1 
ATOM   9175  N N   . MET D 1 166 ? 151.934 123.042 104.392 1.00 14.99  ? 131 MET D N   1 
ATOM   9176  C CA  . MET D 1 166 ? 150.872 123.980 104.707 1.00 15.70  ? 131 MET D CA  1 
ATOM   9177  C C   . MET D 1 166 ? 150.818 124.178 106.212 1.00 14.43  ? 131 MET D C   1 
ATOM   9178  O O   . MET D 1 166 ? 151.084 123.255 106.984 1.00 15.30  ? 131 MET D O   1 
ATOM   9179  C CB  . MET D 1 166 ? 149.513 123.494 104.191 1.00 17.91  ? 131 MET D CB  1 
ATOM   9180  C CG  . MET D 1 166 ? 149.064 122.169 104.780 1.00 20.09  ? 131 MET D CG  1 
ATOM   9181  S SD  . MET D 1 166 ? 147.506 121.600 104.084 1.00 46.16  ? 131 MET D SD  1 
ATOM   9182  C CE  . MET D 1 166 ? 147.993 121.278 102.397 1.00 21.94  ? 131 MET D CE  1 
ATOM   9183  N N   . ARG D 1 167 ? 150.484 125.397 106.619 1.00 13.88  ? 132 ARG D N   1 
ATOM   9184  C CA  . ARG D 1 167 ? 150.344 125.738 108.026 1.00 13.07  ? 132 ARG D CA  1 
ATOM   9185  C C   . ARG D 1 167 ? 148.871 125.626 108.392 1.00 15.21  ? 132 ARG D C   1 
ATOM   9186  O O   . ARG D 1 167 ? 148.026 126.300 107.794 1.00 18.25  ? 132 ARG D O   1 
ATOM   9187  C CB  . ARG D 1 167 ? 150.874 127.144 108.299 1.00 16.15  ? 132 ARG D CB  1 
ATOM   9188  C CG  . ARG D 1 167 ? 150.749 127.593 109.739 1.00 16.80  ? 132 ARG D CG  1 
ATOM   9189  C CD  . ARG D 1 167 ? 151.426 128.934 109.949 1.00 16.19  ? 132 ARG D CD  1 
ATOM   9190  N NE  . ARG D 1 167 ? 150.958 129.592 111.161 1.00 18.07  ? 132 ARG D NE  1 
ATOM   9191  C CZ  . ARG D 1 167 ? 150.094 130.598 111.175 1.00 20.70  ? 132 ARG D CZ  1 
ATOM   9192  N NH1 . ARG D 1 167 ? 149.636 131.130 110.055 1.00 18.91  ? 132 ARG D NH1 1 
ATOM   9193  N NH2 . ARG D 1 167 ? 149.694 131.092 112.342 1.00 23.17  ? 132 ARG D NH2 1 
ATOM   9194  N N   . LEU D 1 168 ? 148.571 124.782 109.375 1.00 16.76  ? 133 LEU D N   1 
ATOM   9195  C CA  . LEU D 1 168 ? 147.203 124.438 109.726 1.00 18.25  ? 133 LEU D CA  1 
ATOM   9196  C C   . LEU D 1 168 ? 146.963 124.642 111.212 1.00 16.90  ? 133 LEU D C   1 
ATOM   9197  O O   . LEU D 1 168 ? 147.872 124.498 112.033 1.00 18.48  ? 133 LEU D O   1 
ATOM   9198  C CB  . LEU D 1 168 ? 146.880 122.981 109.370 1.00 14.92  ? 133 LEU D CB  1 
ATOM   9199  C CG  . LEU D 1 168 ? 147.046 122.535 107.921 1.00 14.80  ? 133 LEU D CG  1 
ATOM   9200  C CD1 . LEU D 1 168 ? 146.891 121.034 107.821 1.00 14.17  ? 133 LEU D CD1 1 
ATOM   9201  C CD2 . LEU D 1 168 ? 146.025 123.229 107.044 1.00 18.33  ? 133 LEU D CD2 1 
ATOM   9202  N N   . THR D 1 169 ? 145.723 124.983 111.547 1.00 17.30  ? 134 THR D N   1 
ATOM   9203  C CA  . THR D 1 169 ? 145.222 124.900 112.911 1.00 19.52  ? 134 THR D CA  1 
ATOM   9204  C C   . THR D 1 169 ? 144.102 123.873 112.899 1.00 22.35  ? 134 THR D C   1 
ATOM   9205  O O   . THR D 1 169 ? 143.116 124.036 112.174 1.00 23.68  ? 134 THR D O   1 
ATOM   9206  C CB  . THR D 1 169 ? 144.718 126.255 113.411 1.00 25.20  ? 134 THR D CB  1 
ATOM   9207  O OG1 . THR D 1 169 ? 145.824 127.155 113.556 1.00 30.16  ? 134 THR D OG1 1 
ATOM   9208  C CG2 . THR D 1 169 ? 144.020 126.102 114.751 1.00 24.40  ? 134 THR D CG2 1 
ATOM   9209  N N   . VAL D 1 170 ? 144.252 122.823 113.700 1.00 24.26  ? 135 VAL D N   1 
ATOM   9210  C CA  . VAL D 1 170 ? 143.353 121.677 113.674 1.00 20.84  ? 135 VAL D CA  1 
ATOM   9211  C C   . VAL D 1 170 ? 142.711 121.522 115.042 1.00 23.32  ? 135 VAL D C   1 
ATOM   9212  O O   . VAL D 1 170 ? 143.411 121.471 116.060 1.00 27.22  ? 135 VAL D O   1 
ATOM   9213  C CB  . VAL D 1 170 ? 144.097 120.389 113.277 1.00 14.58  ? 135 VAL D CB  1 
ATOM   9214  C CG1 . VAL D 1 170 ? 143.148 119.207 113.279 1.00 16.03  ? 135 VAL D CG1 1 
ATOM   9215  C CG2 . VAL D 1 170 ? 144.754 120.553 111.921 1.00 15.72  ? 135 VAL D CG2 1 
ATOM   9216  N N   . ARG D 1 171 ? 141.385 121.451 115.066 1.00 19.03  ? 136 ARG D N   1 
ATOM   9217  C CA  . ARG D 1 171 ? 140.653 120.944 116.215 1.00 20.76  ? 136 ARG D CA  1 
ATOM   9218  C C   . ARG D 1 171 ? 140.359 119.471 115.970 1.00 22.99  ? 136 ARG D C   1 
ATOM   9219  O O   . ARG D 1 171 ? 139.823 119.111 114.918 1.00 24.34  ? 136 ARG D O   1 
ATOM   9220  C CB  . ARG D 1 171 ? 139.356 121.725 116.414 1.00 24.47  ? 136 ARG D CB  1 
ATOM   9221  C CG  . ARG D 1 171 ? 139.558 123.157 116.866 1.00 25.09  ? 136 ARG D CG  1 
ATOM   9222  C CD  . ARG D 1 171 ? 138.581 123.528 117.960 1.00 27.25  ? 136 ARG D CD  1 
ATOM   9223  N NE  . ARG D 1 171 ? 137.228 123.094 117.632 1.00 36.09  ? 136 ARG D NE  1 
ATOM   9224  C CZ  . ARG D 1 171 ? 136.369 123.795 116.905 1.00 35.55  ? 136 ARG D CZ  1 
ATOM   9225  N NH1 . ARG D 1 171 ? 136.697 124.967 116.388 1.00 40.80  ? 136 ARG D NH1 1 
ATOM   9226  N NH2 . ARG D 1 171 ? 135.154 123.302 116.683 1.00 27.53  ? 136 ARG D NH2 1 
ATOM   9227  N N   . ALA D 1 172 ? 140.706 118.623 116.934 1.00 22.19  ? 137 ALA D N   1 
ATOM   9228  C CA  . ALA D 1 172 ? 140.566 117.184 116.776 1.00 20.04  ? 137 ALA D CA  1 
ATOM   9229  C C   . ALA D 1 172 ? 139.788 116.596 117.943 1.00 23.23  ? 137 ALA D C   1 
ATOM   9230  O O   . ALA D 1 172 ? 139.864 117.091 119.069 1.00 27.46  ? 137 ALA D O   1 
ATOM   9231  C CB  . ALA D 1 172 ? 141.934 116.501 116.665 1.00 20.82  ? 137 ALA D CB  1 
ATOM   9232  N N   . GLU D 1 173 ? 139.050 115.523 117.669 1.00 24.27  ? 138 GLU D N   1 
ATOM   9233  C CA  . GLU D 1 173 ? 138.314 114.832 118.718 1.00 24.23  ? 138 GLU D CA  1 
ATOM   9234  C C   . GLU D 1 173 ? 139.271 113.993 119.551 1.00 30.95  ? 138 GLU D C   1 
ATOM   9235  O O   . GLU D 1 173 ? 140.031 113.181 119.014 1.00 36.45  ? 138 GLU D O   1 
ATOM   9236  C CB  . GLU D 1 173 ? 137.220 113.932 118.139 1.00 23.97  ? 138 GLU D CB  1 
ATOM   9237  C CG  . GLU D 1 173 ? 136.262 114.596 117.177 1.00 26.98  ? 138 GLU D CG  1 
ATOM   9238  C CD  . GLU D 1 173 ? 135.462 113.593 116.368 1.00 39.05  ? 138 GLU D CD  1 
ATOM   9239  O OE1 . GLU D 1 173 ? 135.191 112.491 116.890 1.00 46.74  ? 138 GLU D OE1 1 
ATOM   9240  O OE2 . GLU D 1 173 ? 135.104 113.906 115.213 1.00 32.92  ? 138 GLU D OE2 1 
ATOM   9241  N N   . CYS D 1 174 ? 139.227 114.185 120.864 1.00 30.67  ? 139 CYS D N   1 
ATOM   9242  C CA  . CYS D 1 174 ? 140.019 113.405 121.811 1.00 38.53  ? 139 CYS D CA  1 
ATOM   9243  C C   . CYS D 1 174 ? 139.041 112.882 122.849 1.00 47.55  ? 139 CYS D C   1 
ATOM   9244  O O   . CYS D 1 174 ? 138.846 113.504 123.903 1.00 54.95  ? 139 CYS D O   1 
ATOM   9245  C CB  . CYS D 1 174 ? 141.135 114.235 122.449 1.00 37.84  ? 139 CYS D CB  1 
ATOM   9246  S SG  . CYS D 1 174 ? 142.096 113.326 123.693 1.00 70.65  ? 139 CYS D SG  1 
ATOM   9247  N N   . PRO D 1 175 ? 138.383 111.756 122.573 1.00 46.71  ? 140 PRO D N   1 
ATOM   9248  C CA  . PRO D 1 175 ? 137.483 111.174 123.572 1.00 44.19  ? 140 PRO D CA  1 
ATOM   9249  C C   . PRO D 1 175 ? 138.239 110.877 124.854 1.00 46.49  ? 140 PRO D C   1 
ATOM   9250  O O   . PRO D 1 175 ? 139.354 110.353 124.835 1.00 50.49  ? 140 PRO D O   1 
ATOM   9251  C CB  . PRO D 1 175 ? 136.983 109.890 122.899 1.00 43.11  ? 140 PRO D CB  1 
ATOM   9252  C CG  . PRO D 1 175 ? 137.201 110.109 121.443 1.00 43.24  ? 140 PRO D CG  1 
ATOM   9253  C CD  . PRO D 1 175 ? 138.424 110.964 121.333 1.00 42.04  ? 140 PRO D CD  1 
ATOM   9254  N N   . MET D 1 176 ? 137.620 111.219 125.975 1.00 41.20  ? 141 MET D N   1 
ATOM   9255  C CA  . MET D 1 176 ? 138.256 111.095 127.273 1.00 45.10  ? 141 MET D CA  1 
ATOM   9256  C C   . MET D 1 176 ? 137.426 110.217 128.193 1.00 50.52  ? 141 MET D C   1 
ATOM   9257  O O   . MET D 1 176 ? 136.196 110.329 128.238 1.00 52.49  ? 141 MET D O   1 
ATOM   9258  C CB  . MET D 1 176 ? 138.458 112.471 127.910 1.00 39.65  ? 141 MET D CB  1 
ATOM   9259  C CG  . MET D 1 176 ? 139.270 113.426 127.057 1.00 41.11  ? 141 MET D CG  1 
ATOM   9260  S SD  . MET D 1 176 ? 139.573 115.008 127.860 1.00 53.42  ? 141 MET D SD  1 
ATOM   9261  C CE  . MET D 1 176 ? 140.164 115.969 126.472 1.00 45.28  ? 141 MET D CE  1 
ATOM   9262  N N   . HIS D 1 177 ? 138.109 109.345 128.923 1.00 47.59  ? 142 HIS D N   1 
ATOM   9263  C CA  . HIS D 1 177 ? 137.502 108.550 129.982 1.00 47.89  ? 142 HIS D CA  1 
ATOM   9264  C C   . HIS D 1 177 ? 137.877 109.269 131.270 1.00 45.66  ? 142 HIS D C   1 
ATOM   9265  O O   . HIS D 1 177 ? 138.987 109.114 131.784 1.00 51.21  ? 142 HIS D O   1 
ATOM   9266  C CB  . HIS D 1 177 ? 137.991 107.107 129.953 1.00 56.92  ? 142 HIS D CB  1 
ATOM   9267  C CG  . HIS D 1 177 ? 137.435 106.307 128.817 1.00 65.19  ? 142 HIS D CG  1 
ATOM   9268  N ND1 . HIS D 1 177 ? 137.414 106.772 127.520 1.00 60.51  ? 142 HIS D ND1 1 
ATOM   9269  C CD2 . HIS D 1 177 ? 136.872 105.077 128.784 1.00 72.79  ? 142 HIS D CD2 1 
ATOM   9270  C CE1 . HIS D 1 177 ? 136.866 105.861 126.736 1.00 62.87  ? 142 HIS D CE1 1 
ATOM   9271  N NE2 . HIS D 1 177 ? 136.529 104.822 127.479 1.00 72.00  ? 142 HIS D NE2 1 
ATOM   9272  N N   . LEU D 1 178 ? 136.938 110.056 131.791 1.00 39.06  ? 143 LEU D N   1 
ATOM   9273  C CA  . LEU D 1 178 ? 137.196 110.947 132.912 1.00 37.47  ? 143 LEU D CA  1 
ATOM   9274  C C   . LEU D 1 178 ? 136.858 110.317 134.252 1.00 40.54  ? 143 LEU D C   1 
ATOM   9275  O O   . LEU D 1 178 ? 136.557 111.034 135.211 1.00 38.81  ? 143 LEU D O   1 
ATOM   9276  C CB  . LEU D 1 178 ? 136.410 112.243 132.719 1.00 31.64  ? 143 LEU D CB  1 
ATOM   9277  C CG  . LEU D 1 178 ? 136.748 113.003 131.436 1.00 33.32  ? 143 LEU D CG  1 
ATOM   9278  C CD1 . LEU D 1 178 ? 135.750 114.108 131.203 1.00 35.94  ? 143 LEU D CD1 1 
ATOM   9279  C CD2 . LEU D 1 178 ? 138.151 113.566 131.486 1.00 32.01  ? 143 LEU D CD2 1 
ATOM   9280  N N   . GLU D 1 179 ? 136.921 108.989 134.348 1.00 42.68  ? 144 GLU D N   1 
ATOM   9281  C CA  . GLU D 1 179 ? 136.602 108.329 135.606 1.00 39.54  ? 144 GLU D CA  1 
ATOM   9282  C C   . GLU D 1 179 ? 137.680 108.566 136.654 1.00 35.73  ? 144 GLU D C   1 
ATOM   9283  O O   . GLU D 1 179 ? 137.390 108.539 137.854 1.00 40.74  ? 144 GLU D O   1 
ATOM   9284  C CB  . GLU D 1 179 ? 136.404 106.832 135.373 1.00 46.94  ? 144 GLU D CB  1 
ATOM   9285  C CG  . GLU D 1 179 ? 135.241 106.504 134.455 1.00 55.60  ? 144 GLU D CG  1 
ATOM   9286  C CD  . GLU D 1 179 ? 135.262 105.065 133.985 1.00 71.22  ? 144 GLU D CD  1 
ATOM   9287  O OE1 . GLU D 1 179 ? 136.047 104.269 134.541 1.00 75.25  ? 144 GLU D OE1 1 
ATOM   9288  O OE2 . GLU D 1 179 ? 134.494 104.729 133.059 1.00 75.76  ? 144 GLU D OE2 1 
ATOM   9289  N N   . ASP D 1 180 ? 138.921 108.792 136.229 1.00 33.89  ? 145 ASP D N   1 
ATOM   9290  C CA  . ASP D 1 180 ? 140.010 109.072 137.152 1.00 35.45  ? 145 ASP D CA  1 
ATOM   9291  C C   . ASP D 1 180 ? 140.249 110.563 137.355 1.00 35.47  ? 145 ASP D C   1 
ATOM   9292  O O   . ASP D 1 180 ? 141.208 110.929 138.041 1.00 35.01  ? 145 ASP D O   1 
ATOM   9293  C CB  . ASP D 1 180 ? 141.298 108.416 136.647 1.00 38.81  ? 145 ASP D CB  1 
ATOM   9294  C CG  . ASP D 1 180 ? 141.300 106.914 136.835 1.00 45.46  ? 145 ASP D CG  1 
ATOM   9295  O OD1 . ASP D 1 180 ? 140.225 106.351 137.129 1.00 49.07  ? 145 ASP D OD1 1 
ATOM   9296  O OD2 . ASP D 1 180 ? 142.372 106.294 136.677 1.00 46.05  ? 145 ASP D OD2 1 
ATOM   9297  N N   . PHE D 1 181 ? 139.420 111.419 136.764 1.00 32.05  ? 146 PHE D N   1 
ATOM   9298  C CA  . PHE D 1 181 ? 139.598 112.859 136.886 1.00 29.85  ? 146 PHE D CA  1 
ATOM   9299  C C   . PHE D 1 181 ? 139.629 113.260 138.359 1.00 30.05  ? 146 PHE D C   1 
ATOM   9300  O O   . PHE D 1 181 ? 138.807 112.779 139.146 1.00 33.00  ? 146 PHE D O   1 
ATOM   9301  C CB  . PHE D 1 181 ? 138.466 113.587 136.151 1.00 29.68  ? 146 PHE D CB  1 
ATOM   9302  C CG  . PHE D 1 181 ? 138.505 115.091 136.273 1.00 28.81  ? 146 PHE D CG  1 
ATOM   9303  C CD1 . PHE D 1 181 ? 138.018 115.736 137.398 1.00 29.82  ? 146 PHE D CD1 1 
ATOM   9304  C CD2 . PHE D 1 181 ? 139.013 115.861 135.241 1.00 27.69  ? 146 PHE D CD2 1 
ATOM   9305  C CE1 . PHE D 1 181 ? 138.056 117.113 137.497 1.00 29.20  ? 146 PHE D CE1 1 
ATOM   9306  C CE2 . PHE D 1 181 ? 139.049 117.238 135.334 1.00 25.17  ? 146 PHE D CE2 1 
ATOM   9307  C CZ  . PHE D 1 181 ? 138.570 117.863 136.462 1.00 26.34  ? 146 PHE D CZ  1 
ATOM   9308  N N   . PRO D 1 182 ? 140.547 114.145 138.771 1.00 27.55  ? 147 PRO D N   1 
ATOM   9309  C CA  . PRO D 1 182 ? 141.530 114.897 137.985 1.00 27.58  ? 147 PRO D CA  1 
ATOM   9310  C C   . PRO D 1 182 ? 142.868 114.173 137.852 1.00 30.48  ? 147 PRO D C   1 
ATOM   9311  O O   . PRO D 1 182 ? 143.849 114.769 137.421 1.00 30.95  ? 147 PRO D O   1 
ATOM   9312  C CB  . PRO D 1 182 ? 141.664 116.190 138.788 1.00 26.80  ? 147 PRO D CB  1 
ATOM   9313  C CG  . PRO D 1 182 ? 141.553 115.721 140.205 1.00 25.07  ? 147 PRO D CG  1 
ATOM   9314  C CD  . PRO D 1 182 ? 140.569 114.568 140.182 1.00 26.52  ? 147 PRO D CD  1 
ATOM   9315  N N   . MET D 1 183 ? 142.945 112.892 138.205 1.00 30.93  ? 148 MET D N   1 
ATOM   9316  C CA  . MET D 1 183 ? 144.189 112.126 138.133 1.00 30.84  ? 148 MET D CA  1 
ATOM   9317  C C   . MET D 1 183 ? 144.228 111.240 136.902 1.00 31.83  ? 148 MET D C   1 
ATOM   9318  O O   . MET D 1 183 ? 144.770 110.132 136.928 1.00 40.08  ? 148 MET D O   1 
ATOM   9319  C CB  . MET D 1 183 ? 144.367 111.290 139.394 1.00 29.69  ? 148 MET D CB  1 
ATOM   9320  C CG  . MET D 1 183 ? 144.726 112.099 140.615 1.00 30.20  ? 148 MET D CG  1 
ATOM   9321  S SD  . MET D 1 183 ? 144.185 111.318 142.139 1.00 51.42  ? 148 MET D SD  1 
ATOM   9322  C CE  . MET D 1 183 ? 142.428 111.642 142.065 1.00 35.74  ? 148 MET D CE  1 
ATOM   9323  N N   . ASP D 1 184 ? 143.656 111.721 135.810 1.00 27.75  ? 149 ASP D N   1 
ATOM   9324  C CA  . ASP D 1 184 ? 143.503 110.956 134.586 1.00 26.99  ? 149 ASP D CA  1 
ATOM   9325  C C   . ASP D 1 184 ? 144.587 111.323 133.582 1.00 25.48  ? 149 ASP D C   1 
ATOM   9326  O O   . ASP D 1 184 ? 145.124 112.432 133.591 1.00 29.38  ? 149 ASP D O   1 
ATOM   9327  C CB  . ASP D 1 184 ? 142.116 111.177 133.977 1.00 28.46  ? 149 ASP D CB  1 
ATOM   9328  C CG  . ASP D 1 184 ? 141.819 112.639 133.699 1.00 27.67  ? 149 ASP D CG  1 
ATOM   9329  O OD1 . ASP D 1 184 ? 142.656 113.504 134.022 1.00 29.31  ? 149 ASP D OD1 1 
ATOM   9330  O OD2 . ASP D 1 184 ? 140.734 112.926 133.160 1.00 28.05  ? 149 ASP D OD2 1 
ATOM   9331  N N   . ALA D 1 185 ? 144.918 110.363 132.728 1.00 25.81  ? 150 ALA D N   1 
ATOM   9332  C CA  . ALA D 1 185 ? 145.849 110.585 131.638 1.00 22.89  ? 150 ALA D CA  1 
ATOM   9333  C C   . ALA D 1 185 ? 145.176 110.150 130.349 1.00 23.91  ? 150 ALA D C   1 
ATOM   9334  O O   . ALA D 1 185 ? 144.386 109.202 130.332 1.00 25.40  ? 150 ALA D O   1 
ATOM   9335  C CB  . ALA D 1 185 ? 147.160 109.817 131.839 1.00 20.45  ? 150 ALA D CB  1 
ATOM   9336  N N   . HIS D 1 186 ? 145.498 110.845 129.267 1.00 25.08  ? 151 HIS D N   1 
ATOM   9337  C CA  . HIS D 1 186 ? 144.880 110.586 127.980 1.00 26.75  ? 151 HIS D CA  1 
ATOM   9338  C C   . HIS D 1 186 ? 145.936 110.556 126.892 1.00 24.52  ? 151 HIS D C   1 
ATOM   9339  O O   . HIS D 1 186 ? 146.981 111.203 126.995 1.00 29.37  ? 151 HIS D O   1 
ATOM   9340  C CB  . HIS D 1 186 ? 143.837 111.651 127.624 1.00 27.15  ? 151 HIS D CB  1 
ATOM   9341  C CG  . HIS D 1 186 ? 142.861 111.934 128.721 1.00 30.82  ? 151 HIS D CG  1 
ATOM   9342  N ND1 . HIS D 1 186 ? 143.029 112.971 129.612 1.00 29.58  ? 151 HIS D ND1 1 
ATOM   9343  C CD2 . HIS D 1 186 ? 141.709 111.317 129.072 1.00 35.64  ? 151 HIS D CD2 1 
ATOM   9344  C CE1 . HIS D 1 186 ? 142.020 112.982 130.464 1.00 32.71  ? 151 HIS D CE1 1 
ATOM   9345  N NE2 . HIS D 1 186 ? 141.205 111.988 130.159 1.00 37.72  ? 151 HIS D NE2 1 
ATOM   9346  N N   . ALA D 1 187 ? 145.648 109.797 125.847 1.00 22.97  ? 152 ALA D N   1 
ATOM   9347  C CA  . ALA D 1 187 ? 146.467 109.772 124.647 1.00 25.46  ? 152 ALA D CA  1 
ATOM   9348  C C   . ALA D 1 187 ? 145.582 110.363 123.557 1.00 29.36  ? 152 ALA D C   1 
ATOM   9349  O O   . ALA D 1 187 ? 144.807 109.654 122.914 1.00 29.32  ? 152 ALA D O   1 
ATOM   9350  C CB  . ALA D 1 187 ? 146.931 108.361 124.308 1.00 24.49  ? 152 ALA D CB  1 
ATOM   9351  N N   . CYS D 1 188 ? 145.702 111.666 123.353 1.00 27.56  ? 153 CYS D N   1 
ATOM   9352  C CA  . CYS D 1 188 ? 144.879 112.322 122.352 1.00 24.57  ? 153 CYS D CA  1 
ATOM   9353  C C   . CYS D 1 188 ? 145.421 111.968 120.979 1.00 24.63  ? 153 CYS D C   1 
ATOM   9354  O O   . CYS D 1 188 ? 146.605 112.206 120.709 1.00 26.16  ? 153 CYS D O   1 
ATOM   9355  C CB  . CYS D 1 188 ? 144.852 113.834 122.551 1.00 26.43  ? 153 CYS D CB  1 
ATOM   9356  S SG  . CYS D 1 188 ? 143.821 114.378 123.932 1.00 79.31  ? 153 CYS D SG  1 
ATOM   9357  N N   . PRO D 1 189 ? 144.612 111.415 120.092 1.00 25.69  ? 154 PRO D N   1 
ATOM   9358  C CA  . PRO D 1 189 ? 145.120 110.956 118.802 1.00 22.99  ? 154 PRO D CA  1 
ATOM   9359  C C   . PRO D 1 189 ? 145.040 112.042 117.738 1.00 18.93  ? 154 PRO D C   1 
ATOM   9360  O O   . PRO D 1 189 ? 144.390 113.075 117.902 1.00 23.13  ? 154 PRO D O   1 
ATOM   9361  C CB  . PRO D 1 189 ? 144.178 109.795 118.467 1.00 25.08  ? 154 PRO D CB  1 
ATOM   9362  C CG  . PRO D 1 189 ? 142.877 110.220 119.060 1.00 28.51  ? 154 PRO D CG  1 
ATOM   9363  C CD  . PRO D 1 189 ? 143.201 111.039 120.292 1.00 27.63  ? 154 PRO D CD  1 
ATOM   9364  N N   . LEU D 1 190 ? 145.723 111.774 116.633 1.00 15.54  ? 155 LEU D N   1 
ATOM   9365  C CA  . LEU D 1 190 ? 145.673 112.628 115.453 1.00 17.93  ? 155 LEU D CA  1 
ATOM   9366  C C   . LEU D 1 190 ? 145.900 111.687 114.278 1.00 18.90  ? 155 LEU D C   1 
ATOM   9367  O O   . LEU D 1 190 ? 147.039 111.323 113.976 1.00 24.38  ? 155 LEU D O   1 
ATOM   9368  C CB  . LEU D 1 190 ? 146.717 113.734 115.500 1.00 18.88  ? 155 LEU D CB  1 
ATOM   9369  C CG  . LEU D 1 190 ? 146.717 114.667 114.286 1.00 14.50  ? 155 LEU D CG  1 
ATOM   9370  C CD1 . LEU D 1 190 ? 145.461 115.519 114.249 1.00 14.91  ? 155 LEU D CD1 1 
ATOM   9371  C CD2 . LEU D 1 190 ? 147.961 115.539 114.273 1.00 11.97  ? 155 LEU D CD2 1 
ATOM   9372  N N   . LYS D 1 191 ? 144.811 111.310 113.628 1.00 13.02  ? 156 LYS D N   1 
ATOM   9373  C CA  . LYS D 1 191 ? 144.830 110.341 112.550 1.00 13.77  ? 156 LYS D CA  1 
ATOM   9374  C C   . LYS D 1 191 ? 144.544 111.054 111.243 1.00 15.78  ? 156 LYS D C   1 
ATOM   9375  O O   . LYS D 1 191 ? 143.736 111.985 111.199 1.00 17.90  ? 156 LYS D O   1 
ATOM   9376  C CB  . LYS D 1 191 ? 143.793 109.244 112.786 1.00 14.71  ? 156 LYS D CB  1 
ATOM   9377  C CG  . LYS D 1 191 ? 143.711 108.777 114.225 1.00 15.48  ? 156 LYS D CG  1 
ATOM   9378  C CD  . LYS D 1 191 ? 142.827 107.553 114.363 1.00 16.65  ? 156 LYS D CD  1 
ATOM   9379  C CE  . LYS D 1 191 ? 142.965 106.933 115.743 1.00 21.43  ? 156 LYS D CE  1 
ATOM   9380  N NZ  . LYS D 1 191 ? 142.197 105.665 115.864 1.00 24.17  ? 156 LYS D NZ  1 
ATOM   9381  N N   . PHE D 1 192 ? 145.211 110.622 110.180 1.00 14.51  ? 157 PHE D N   1 
ATOM   9382  C CA  . PHE D 1 192 ? 144.905 111.166 108.872 1.00 14.17  ? 157 PHE D CA  1 
ATOM   9383  C C   . PHE D 1 192 ? 145.138 110.098 107.820 1.00 15.32  ? 157 PHE D C   1 
ATOM   9384  O O   . PHE D 1 192 ? 145.821 109.098 108.051 1.00 20.71  ? 157 PHE D O   1 
ATOM   9385  C CB  . PHE D 1 192 ? 145.736 112.422 108.567 1.00 15.69  ? 157 PHE D CB  1 
ATOM   9386  C CG  . PHE D 1 192 ? 147.221 112.222 108.680 1.00 17.10  ? 157 PHE D CG  1 
ATOM   9387  C CD1 . PHE D 1 192 ? 147.865 112.389 109.894 1.00 15.21  ? 157 PHE D CD1 1 
ATOM   9388  C CD2 . PHE D 1 192 ? 147.974 111.877 107.573 1.00 17.79  ? 157 PHE D CD2 1 
ATOM   9389  C CE1 . PHE D 1 192 ? 149.229 112.211 110.000 1.00 16.96  ? 157 PHE D CE1 1 
ATOM   9390  C CE2 . PHE D 1 192 ? 149.338 111.695 107.674 1.00 17.46  ? 157 PHE D CE2 1 
ATOM   9391  C CZ  . PHE D 1 192 ? 149.965 111.863 108.888 1.00 18.38  ? 157 PHE D CZ  1 
ATOM   9392  N N   . GLY D 1 193 ? 144.557 110.337 106.655 1.00 14.56  ? 158 GLY D N   1 
ATOM   9393  C CA  . GLY D 1 193 ? 144.671 109.410 105.552 1.00 16.24  ? 158 GLY D CA  1 
ATOM   9394  C C   . GLY D 1 193 ? 143.928 109.967 104.364 1.00 19.65  ? 158 GLY D C   1 
ATOM   9395  O O   . GLY D 1 193 ? 143.438 111.097 104.394 1.00 21.81  ? 158 GLY D O   1 
ATOM   9396  N N   . SER D 1 194 ? 143.831 109.162 103.316 1.00 21.26  ? 159 SER D N   1 
ATOM   9397  C CA  . SER D 1 194 ? 143.082 109.589 102.150 1.00 23.09  ? 159 SER D CA  1 
ATOM   9398  C C   . SER D 1 194 ? 141.596 109.374 102.389 1.00 26.49  ? 159 SER D C   1 
ATOM   9399  O O   . SER D 1 194 ? 141.178 108.338 102.914 1.00 33.10  ? 159 SER D O   1 
ATOM   9400  C CB  . SER D 1 194 ? 143.532 108.825 100.908 1.00 26.47  ? 159 SER D CB  1 
ATOM   9401  O OG  . SER D 1 194 ? 142.907 109.349 99.751  1.00 28.24  ? 159 SER D OG  1 
ATOM   9402  N N   . TYR D 1 195 ? 140.797 110.368 102.006 1.00 23.02  ? 160 TYR D N   1 
ATOM   9403  C CA  . TYR D 1 195 ? 139.359 110.272 102.220 1.00 20.16  ? 160 TYR D CA  1 
ATOM   9404  C C   . TYR D 1 195 ? 138.723 109.316 101.225 1.00 21.71  ? 160 TYR D C   1 
ATOM   9405  O O   . TYR D 1 195 ? 137.811 108.559 101.574 1.00 25.82  ? 160 TYR D O   1 
ATOM   9406  C CB  . TYR D 1 195 ? 138.706 111.651 102.139 1.00 21.20  ? 160 TYR D CB  1 
ATOM   9407  C CG  . TYR D 1 195 ? 137.247 111.624 102.534 1.00 21.55  ? 160 TYR D CG  1 
ATOM   9408  C CD1 . TYR D 1 195 ? 136.867 111.786 103.858 1.00 19.39  ? 160 TYR D CD1 1 
ATOM   9409  C CD2 . TYR D 1 195 ? 136.251 111.440 101.586 1.00 21.48  ? 160 TYR D CD2 1 
ATOM   9410  C CE1 . TYR D 1 195 ? 135.541 111.755 104.228 1.00 18.17  ? 160 TYR D CE1 1 
ATOM   9411  C CE2 . TYR D 1 195 ? 134.922 111.410 101.947 1.00 20.85  ? 160 TYR D CE2 1 
ATOM   9412  C CZ  . TYR D 1 195 ? 134.574 111.570 103.269 1.00 22.82  ? 160 TYR D CZ  1 
ATOM   9413  O OH  . TYR D 1 195 ? 133.250 111.540 103.635 1.00 32.47  ? 160 TYR D OH  1 
ATOM   9414  N N   . ALA D 1 196 ? 139.200 109.331 99.983  1.00 20.80  ? 161 ALA D N   1 
ATOM   9415  C CA  . ALA D 1 196 ? 138.550 108.632 98.890  1.00 21.89  ? 161 ALA D CA  1 
ATOM   9416  C C   . ALA D 1 196 ? 139.365 107.487 98.308  1.00 25.10  ? 161 ALA D C   1 
ATOM   9417  O O   . ALA D 1 196 ? 138.786 106.620 97.649  1.00 25.14  ? 161 ALA D O   1 
ATOM   9418  C CB  . ALA D 1 196 ? 138.211 109.624 97.769  1.00 20.01  ? 161 ALA D CB  1 
ATOM   9419  N N   . TYR D 1 197 ? 140.674 107.449 98.538  1.00 28.18  ? 162 TYR D N   1 
ATOM   9420  C CA  . TYR D 1 197 ? 141.543 106.465 97.906  1.00 31.59  ? 162 TYR D CA  1 
ATOM   9421  C C   . TYR D 1 197 ? 141.844 105.343 98.889  1.00 30.51  ? 162 TYR D C   1 
ATOM   9422  O O   . TYR D 1 197 ? 142.297 105.598 100.010 1.00 28.20  ? 162 TYR D O   1 
ATOM   9423  C CB  . TYR D 1 197 ? 142.851 107.108 97.445  1.00 29.99  ? 162 TYR D CB  1 
ATOM   9424  C CG  . TYR D 1 197 ? 142.700 108.166 96.379  1.00 27.74  ? 162 TYR D CG  1 
ATOM   9425  C CD1 . TYR D 1 197 ? 142.543 107.820 95.048  1.00 31.79  ? 162 TYR D CD1 1 
ATOM   9426  C CD2 . TYR D 1 197 ? 142.723 109.512 96.706  1.00 25.53  ? 162 TYR D CD2 1 
ATOM   9427  C CE1 . TYR D 1 197 ? 142.410 108.786 94.072  1.00 34.97  ? 162 TYR D CE1 1 
ATOM   9428  C CE2 . TYR D 1 197 ? 142.591 110.484 95.740  1.00 26.86  ? 162 TYR D CE2 1 
ATOM   9429  C CZ  . TYR D 1 197 ? 142.434 110.116 94.425  1.00 31.64  ? 162 TYR D CZ  1 
ATOM   9430  O OH  . TYR D 1 197 ? 142.303 111.084 93.457  1.00 36.43  ? 162 TYR D OH  1 
ATOM   9431  N N   . THR D 1 198 ? 141.606 104.107 98.459  1.00 33.99  ? 163 THR D N   1 
ATOM   9432  C CA  . THR D 1 198 ? 141.890 102.940 99.276  1.00 38.63  ? 163 THR D CA  1 
ATOM   9433  C C   . THR D 1 198 ? 143.375 102.591 99.212  1.00 42.46  ? 163 THR D C   1 
ATOM   9434  O O   . THR D 1 198 ? 144.134 103.124 98.396  1.00 41.74  ? 163 THR D O   1 
ATOM   9435  C CB  . THR D 1 198 ? 141.045 101.750 98.826  1.00 38.75  ? 163 THR D CB  1 
ATOM   9436  O OG1 . THR D 1 198 ? 141.299 101.478 97.443  1.00 39.92  ? 163 THR D OG1 1 
ATOM   9437  C CG2 . THR D 1 198 ? 139.570 102.050 99.010  1.00 36.18  ? 163 THR D CG2 1 
ATOM   9438  N N   . ARG D 1 199 ? 143.791 101.679 100.096 1.00 41.96  ? 164 ARG D N   1 
ATOM   9439  C CA  . ARG D 1 199 ? 145.205 101.335 100.192 1.00 41.00  ? 164 ARG D CA  1 
ATOM   9440  C C   . ARG D 1 199 ? 145.732 100.693 98.917  1.00 44.18  ? 164 ARG D C   1 
ATOM   9441  O O   . ARG D 1 199 ? 146.950 100.629 98.726  1.00 43.17  ? 164 ARG D O   1 
ATOM   9442  C CB  . ARG D 1 199 ? 145.451 100.395 101.370 1.00 37.67  ? 164 ARG D CB  1 
ATOM   9443  C CG  . ARG D 1 199 ? 144.766 99.051  101.261 1.00 51.71  ? 164 ARG D CG  1 
ATOM   9444  C CD  . ARG D 1 199 ? 145.400 98.058  102.220 1.00 56.87  ? 164 ARG D CD  1 
ATOM   9445  N NE  . ARG D 1 199 ? 144.897 96.703  102.032 1.00 58.72  ? 164 ARG D NE  1 
ATOM   9446  C CZ  . ARG D 1 199 ? 145.314 95.651  102.722 1.00 57.68  ? 164 ARG D CZ  1 
ATOM   9447  N NH1 . ARG D 1 199 ? 146.245 95.762  103.655 1.00 54.85  ? 164 ARG D NH1 1 
ATOM   9448  N NH2 . ARG D 1 199 ? 144.784 94.458  102.470 1.00 62.74  ? 164 ARG D NH2 1 
ATOM   9449  N N   . ALA D 1 200 ? 144.846 100.210 98.044  1.00 46.85  ? 165 ALA D N   1 
ATOM   9450  C CA  . ALA D 1 200 ? 145.269 99.736  96.734  1.00 47.68  ? 165 ALA D CA  1 
ATOM   9451  C C   . ALA D 1 200 ? 145.644 100.872 95.794  1.00 50.11  ? 165 ALA D C   1 
ATOM   9452  O O   . ALA D 1 200 ? 146.189 100.607 94.717  1.00 52.17  ? 165 ALA D O   1 
ATOM   9453  C CB  . ALA D 1 200 ? 144.166 98.885  96.103  1.00 41.48  ? 165 ALA D CB  1 
ATOM   9454  N N   . GLU D 1 201 ? 145.372 102.120 96.171  1.00 47.10  ? 166 GLU D N   1 
ATOM   9455  C CA  . GLU D 1 201 ? 145.633 103.273 95.319  1.00 48.09  ? 166 GLU D CA  1 
ATOM   9456  C C   . GLU D 1 201 ? 146.620 104.250 95.937  1.00 46.32  ? 166 GLU D C   1 
ATOM   9457  O O   . GLU D 1 201 ? 147.556 104.686 95.256  1.00 48.54  ? 166 GLU D O   1 
ATOM   9458  C CB  . GLU D 1 201 ? 144.317 103.991 94.981  1.00 46.90  ? 166 GLU D CB  1 
ATOM   9459  C CG  . GLU D 1 201 ? 143.152 103.051 94.723  1.00 48.75  ? 166 GLU D CG  1 
ATOM   9460  C CD  . GLU D 1 201 ? 141.881 103.784 94.347  1.00 54.56  ? 166 GLU D CD  1 
ATOM   9461  O OE1 . GLU D 1 201 ? 141.937 104.652 93.451  1.00 59.87  ? 166 GLU D OE1 1 
ATOM   9462  O OE2 . GLU D 1 201 ? 140.824 103.491 94.945  1.00 53.92  ? 166 GLU D OE2 1 
ATOM   9463  N N   . VAL D 1 202 ? 146.435 104.623 97.201  1.00 41.41  ? 167 VAL D N   1 
ATOM   9464  C CA  . VAL D 1 202 ? 147.318 105.569 97.873  1.00 42.00  ? 167 VAL D CA  1 
ATOM   9465  C C   . VAL D 1 202 ? 147.725 104.991 99.221  1.00 36.70  ? 167 VAL D C   1 
ATOM   9466  O O   . VAL D 1 202 ? 146.867 104.582 100.010 1.00 32.88  ? 167 VAL D O   1 
ATOM   9467  C CB  . VAL D 1 202 ? 146.646 106.943 98.060  1.00 36.63  ? 167 VAL D CB  1 
ATOM   9468  C CG1 . VAL D 1 202 ? 147.489 107.827 98.963  1.00 31.02  ? 167 VAL D CG1 1 
ATOM   9469  C CG2 . VAL D 1 202 ? 146.419 107.613 96.714  1.00 38.67  ? 167 VAL D CG2 1 
ATOM   9470  N N   . VAL D 1 203 ? 149.029 104.972 99.486  1.00 42.23  ? 168 VAL D N   1 
ATOM   9471  C CA  . VAL D 1 203 ? 149.586 104.504 100.750 1.00 37.45  ? 168 VAL D CA  1 
ATOM   9472  C C   . VAL D 1 203 ? 150.431 105.624 101.338 1.00 36.40  ? 168 VAL D C   1 
ATOM   9473  O O   . VAL D 1 203 ? 151.225 106.251 100.628 1.00 40.22  ? 168 VAL D O   1 
ATOM   9474  C CB  . VAL D 1 203 ? 150.409 103.212 100.580 1.00 32.56  ? 168 VAL D CB  1 
ATOM   9475  C CG1 . VAL D 1 203 ? 149.511 102.069 100.152 1.00 38.48  ? 168 VAL D CG1 1 
ATOM   9476  C CG2 . VAL D 1 203 ? 151.519 103.403 99.562  1.00 35.18  ? 168 VAL D CG2 1 
ATOM   9477  N N   . TYR D 1 204 ? 150.242 105.891 102.624 1.00 31.43  ? 169 TYR D N   1 
ATOM   9478  C CA  . TYR D 1 204 ? 150.989 106.924 103.324 1.00 28.67  ? 169 TYR D CA  1 
ATOM   9479  C C   . TYR D 1 204 ? 152.102 106.291 104.151 1.00 32.43  ? 169 TYR D C   1 
ATOM   9480  O O   . TYR D 1 204 ? 151.916 105.227 104.748 1.00 37.69  ? 169 TYR D O   1 
ATOM   9481  C CB  . TYR D 1 204 ? 150.061 107.744 104.220 1.00 28.68  ? 169 TYR D CB  1 
ATOM   9482  C CG  . TYR D 1 204 ? 149.120 108.652 103.463 1.00 26.22  ? 169 TYR D CG  1 
ATOM   9483  C CD1 . TYR D 1 204 ? 149.497 109.940 103.116 1.00 26.59  ? 169 TYR D CD1 1 
ATOM   9484  C CD2 . TYR D 1 204 ? 147.860 108.216 103.084 1.00 26.48  ? 169 TYR D CD2 1 
ATOM   9485  C CE1 . TYR D 1 204 ? 148.642 110.773 102.424 1.00 24.81  ? 169 TYR D CE1 1 
ATOM   9486  C CE2 . TYR D 1 204 ? 146.999 109.039 102.389 1.00 23.93  ? 169 TYR D CE2 1 
ATOM   9487  C CZ  . TYR D 1 204 ? 147.395 110.317 102.062 1.00 22.92  ? 169 TYR D CZ  1 
ATOM   9488  O OH  . TYR D 1 204 ? 146.539 111.140 101.370 1.00 21.44  ? 169 TYR D OH  1 
ATOM   9489  N N   . GLU D 1 205 ? 153.261 106.948 104.174 1.00 36.05  ? 170 GLU D N   1 
ATOM   9490  C CA  . GLU D 1 205 ? 154.376 106.537 105.016 1.00 39.50  ? 170 GLU D CA  1 
ATOM   9491  C C   . GLU D 1 205 ? 155.040 107.766 105.620 1.00 37.53  ? 170 GLU D C   1 
ATOM   9492  O O   . GLU D 1 205 ? 154.951 108.871 105.084 1.00 40.45  ? 170 GLU D O   1 
ATOM   9493  C CB  . GLU D 1 205 ? 155.411 105.720 104.229 1.00 41.65  ? 170 GLU D CB  1 
ATOM   9494  C CG  . GLU D 1 205 ? 154.883 104.409 103.671 1.00 48.97  ? 170 GLU D CG  1 
ATOM   9495  C CD  . GLU D 1 205 ? 155.955 103.600 102.970 1.00 59.76  ? 170 GLU D CD  1 
ATOM   9496  O OE1 . GLU D 1 205 ? 157.122 104.043 102.956 1.00 60.59  ? 170 GLU D OE1 1 
ATOM   9497  O OE2 . GLU D 1 205 ? 155.631 102.517 102.442 1.00 66.32  ? 170 GLU D OE2 1 
ATOM   9498  N N   . TRP D 1 206 ? 155.691 107.565 106.763 1.00 33.00  ? 171 TRP D N   1 
ATOM   9499  C CA  . TRP D 1 206 ? 156.479 108.622 107.382 1.00 33.62  ? 171 TRP D CA  1 
ATOM   9500  C C   . TRP D 1 206 ? 157.809 108.787 106.656 1.00 37.69  ? 171 TRP D C   1 
ATOM   9501  O O   . TRP D 1 206 ? 158.403 107.809 106.192 1.00 39.44  ? 171 TRP D O   1 
ATOM   9502  C CB  . TRP D 1 206 ? 156.718 108.308 108.858 1.00 30.39  ? 171 TRP D CB  1 
ATOM   9503  C CG  . TRP D 1 206 ? 155.457 108.271 109.650 1.00 29.78  ? 171 TRP D CG  1 
ATOM   9504  C CD1 . TRP D 1 206 ? 154.840 107.167 110.150 1.00 32.30  ? 171 TRP D CD1 1 
ATOM   9505  C CD2 . TRP D 1 206 ? 154.655 109.391 110.040 1.00 31.17  ? 171 TRP D CD2 1 
ATOM   9506  N NE1 . TRP D 1 206 ? 153.697 107.526 110.819 1.00 33.26  ? 171 TRP D NE1 1 
ATOM   9507  C CE2 . TRP D 1 206 ? 153.561 108.888 110.766 1.00 31.20  ? 171 TRP D CE2 1 
ATOM   9508  C CE3 . TRP D 1 206 ? 154.753 110.771 109.842 1.00 31.22  ? 171 TRP D CE3 1 
ATOM   9509  C CZ2 . TRP D 1 206 ? 152.577 109.713 111.301 1.00 29.01  ? 171 TRP D CZ2 1 
ATOM   9510  C CZ3 . TRP D 1 206 ? 153.772 111.589 110.371 1.00 27.87  ? 171 TRP D CZ3 1 
ATOM   9511  C CH2 . TRP D 1 206 ? 152.700 111.058 111.092 1.00 25.87  ? 171 TRP D CH2 1 
ATOM   9512  N N   . THR D 1 207 ? 158.266 110.038 106.546 1.00 37.15  ? 172 THR D N   1 
ATOM   9513  C CA  . THR D 1 207 ? 159.467 110.324 105.765 1.00 38.71  ? 172 THR D CA  1 
ATOM   9514  C C   . THR D 1 207 ? 160.681 109.605 106.339 1.00 44.82  ? 172 THR D C   1 
ATOM   9515  O O   . THR D 1 207 ? 161.465 108.995 105.603 1.00 49.17  ? 172 THR D O   1 
ATOM   9516  C CB  . THR D 1 207 ? 159.715 111.832 105.720 1.00 37.60  ? 172 THR D CB  1 
ATOM   9517  O OG1 . THR D 1 207 ? 158.572 112.490 105.160 1.00 35.31  ? 172 THR D OG1 1 
ATOM   9518  C CG2 . THR D 1 207 ? 160.941 112.147 104.881 1.00 36.10  ? 172 THR D CG2 1 
ATOM   9519  N N   . ARG D 1 208 ? 160.848 109.664 107.658 1.00 48.02  ? 173 ARG D N   1 
ATOM   9520  C CA  . ARG D 1 208 ? 161.953 108.997 108.334 1.00 48.37  ? 173 ARG D CA  1 
ATOM   9521  C C   . ARG D 1 208 ? 161.400 108.129 109.453 1.00 49.41  ? 173 ARG D C   1 
ATOM   9522  O O   . ARG D 1 208 ? 160.193 107.868 109.495 1.00 49.40  ? 173 ARG D O   1 
ATOM   9523  C CB  . ARG D 1 208 ? 162.959 110.009 108.886 1.00 49.73  ? 173 ARG D CB  1 
ATOM   9524  C CG  . ARG D 1 208 ? 162.388 110.967 109.920 1.00 52.07  ? 173 ARG D CG  1 
ATOM   9525  C CD  . ARG D 1 208 ? 163.298 112.169 110.121 1.00 54.39  ? 173 ARG D CD  1 
ATOM   9526  N NE  . ARG D 1 208 ? 163.155 113.162 109.063 1.00 47.49  ? 173 ARG D NE  1 
ATOM   9527  C CZ  . ARG D 1 208 ? 162.307 114.181 109.102 1.00 41.10  ? 173 ARG D CZ  1 
ATOM   9528  N NH1 . ARG D 1 208 ? 161.502 114.371 110.134 1.00 41.49  ? 173 ARG D NH1 1 
ATOM   9529  N NH2 . ARG D 1 208 ? 162.265 115.029 108.079 1.00 38.36  ? 173 ARG D NH2 1 
ATOM   9530  N N   . GLU D 1 209 ? 162.278 107.647 110.331 1.00 54.07  ? 174 GLU D N   1 
ATOM   9531  C CA  . GLU D 1 209 ? 161.897 106.808 111.456 1.00 57.25  ? 174 GLU D CA  1 
ATOM   9532  C C   . GLU D 1 209 ? 160.680 107.406 112.162 1.00 52.10  ? 174 GLU D C   1 
ATOM   9533  O O   . GLU D 1 209 ? 160.738 108.563 112.602 1.00 53.81  ? 174 GLU D O   1 
ATOM   9534  C CB  . GLU D 1 209 ? 163.060 106.663 112.435 1.00 60.72  ? 174 GLU D CB  1 
ATOM   9535  C CG  . GLU D 1 209 ? 164.253 105.892 111.882 1.00 66.78  ? 174 GLU D CG  1 
ATOM   9536  C CD  . GLU D 1 209 ? 165.143 106.736 110.989 1.00 72.27  ? 174 GLU D CD  1 
ATOM   9537  O OE1 . GLU D 1 209 ? 165.005 107.977 111.007 1.00 71.56  ? 174 GLU D OE1 1 
ATOM   9538  O OE2 . GLU D 1 209 ? 165.982 106.156 110.268 1.00 77.32  ? 174 GLU D OE2 1 
ATOM   9539  N N   . PRO D 1 210 ? 159.558 106.669 112.255 1.00 46.02  ? 175 PRO D N   1 
ATOM   9540  C CA  . PRO D 1 210 ? 158.310 107.234 112.797 1.00 42.81  ? 175 PRO D CA  1 
ATOM   9541  C C   . PRO D 1 210 ? 158.464 108.114 114.029 1.00 42.35  ? 175 PRO D C   1 
ATOM   9542  O O   . PRO D 1 210 ? 157.745 109.107 114.171 1.00 41.02  ? 175 PRO D O   1 
ATOM   9543  C CB  . PRO D 1 210 ? 157.488 105.981 113.119 1.00 44.62  ? 175 PRO D CB  1 
ATOM   9544  C CG  . PRO D 1 210 ? 157.932 104.993 112.097 1.00 50.25  ? 175 PRO D CG  1 
ATOM   9545  C CD  . PRO D 1 210 ? 159.397 105.262 111.851 1.00 48.74  ? 175 PRO D CD  1 
ATOM   9546  N N   . ALA D 1 211 ? 159.388 107.764 114.926 1.00 45.18  ? 176 ALA D N   1 
ATOM   9547  C CA  . ALA D 1 211 ? 159.607 108.590 116.109 1.00 45.72  ? 176 ALA D CA  1 
ATOM   9548  C C   . ALA D 1 211 ? 160.101 109.981 115.731 1.00 43.19  ? 176 ALA D C   1 
ATOM   9549  O O   . ALA D 1 211 ? 159.684 110.980 116.330 1.00 39.74  ? 176 ALA D O   1 
ATOM   9550  C CB  . ALA D 1 211 ? 160.596 107.905 117.052 1.00 51.18  ? 176 ALA D CB  1 
ATOM   9551  N N   . ARG D 1 212 ? 160.989 110.068 114.745 1.00 45.36  ? 177 ARG D N   1 
ATOM   9552  C CA  . ARG D 1 212 ? 161.591 111.333 114.341 1.00 44.40  ? 177 ARG D CA  1 
ATOM   9553  C C   . ARG D 1 212 ? 160.814 112.049 113.242 1.00 43.20  ? 177 ARG D C   1 
ATOM   9554  O O   . ARG D 1 212 ? 161.227 113.135 112.824 1.00 40.53  ? 177 ARG D O   1 
ATOM   9555  C CB  . ARG D 1 212 ? 163.037 111.107 113.888 1.00 49.35  ? 177 ARG D CB  1 
ATOM   9556  C CG  . ARG D 1 212 ? 163.912 110.452 114.945 1.00 56.84  ? 177 ARG D CG  1 
ATOM   9557  C CD  . ARG D 1 212 ? 165.405 110.609 114.663 1.00 66.95  ? 177 ARG D CD  1 
ATOM   9558  N NE  . ARG D 1 212 ? 165.801 110.096 113.357 1.00 73.82  ? 177 ARG D NE  1 
ATOM   9559  C CZ  . ARG D 1 212 ? 165.962 110.844 112.273 1.00 72.17  ? 177 ARG D CZ  1 
ATOM   9560  N NH1 . ARG D 1 212 ? 165.763 112.152 112.301 1.00 65.31  ? 177 ARG D NH1 1 
ATOM   9561  N NH2 . ARG D 1 212 ? 166.331 110.265 111.134 1.00 69.80  ? 177 ARG D NH2 1 
ATOM   9562  N N   . SER D 1 213 ? 159.708 111.476 112.764 1.00 43.07  ? 178 SER D N   1 
ATOM   9563  C CA  . SER D 1 213 ? 158.951 112.108 111.688 1.00 36.01  ? 178 SER D CA  1 
ATOM   9564  C C   . SER D 1 213 ? 157.999 113.175 112.210 1.00 32.97  ? 178 SER D C   1 
ATOM   9565  O O   . SER D 1 213 ? 157.641 114.095 111.468 1.00 33.11  ? 178 SER D O   1 
ATOM   9566  C CB  . SER D 1 213 ? 158.174 111.056 110.898 1.00 34.91  ? 178 SER D CB  1 
ATOM   9567  O OG  . SER D 1 213 ? 159.051 110.197 110.193 1.00 37.65  ? 178 SER D OG  1 
ATOM   9568  N N   . VAL D 1 214 ? 157.579 113.070 113.467 1.00 32.54  ? 179 VAL D N   1 
ATOM   9569  C CA  . VAL D 1 214 ? 156.766 114.085 114.128 1.00 29.96  ? 179 VAL D CA  1 
ATOM   9570  C C   . VAL D 1 214 ? 157.662 114.809 115.121 1.00 32.21  ? 179 VAL D C   1 
ATOM   9571  O O   . VAL D 1 214 ? 158.223 114.186 116.031 1.00 34.88  ? 179 VAL D O   1 
ATOM   9572  C CB  . VAL D 1 214 ? 155.543 113.472 114.825 1.00 30.44  ? 179 VAL D CB  1 
ATOM   9573  C CG1 . VAL D 1 214 ? 154.794 114.536 115.610 1.00 29.07  ? 179 VAL D CG1 1 
ATOM   9574  C CG2 . VAL D 1 214 ? 154.629 112.818 113.803 1.00 27.23  ? 179 VAL D CG2 1 
ATOM   9575  N N   . VAL D 1 215 ? 157.792 116.122 114.952 1.00 32.46  ? 180 VAL D N   1 
ATOM   9576  C CA  . VAL D 1 215 ? 158.691 116.943 115.753 1.00 31.79  ? 180 VAL D CA  1 
ATOM   9577  C C   . VAL D 1 215 ? 157.882 118.046 116.417 1.00 31.26  ? 180 VAL D C   1 
ATOM   9578  O O   . VAL D 1 215 ? 157.084 118.721 115.757 1.00 30.23  ? 180 VAL D O   1 
ATOM   9579  C CB  . VAL D 1 215 ? 159.824 117.538 114.896 1.00 27.19  ? 180 VAL D CB  1 
ATOM   9580  C CG1 . VAL D 1 215 ? 160.663 118.503 115.714 1.00 27.02  ? 180 VAL D CG1 1 
ATOM   9581  C CG2 . VAL D 1 215 ? 160.688 116.432 114.314 1.00 28.45  ? 180 VAL D CG2 1 
ATOM   9582  N N   . VAL D 1 216 ? 158.086 118.222 117.718 1.00 30.57  ? 181 VAL D N   1 
ATOM   9583  C CA  . VAL D 1 216 ? 157.398 119.236 118.509 1.00 32.02  ? 181 VAL D CA  1 
ATOM   9584  C C   . VAL D 1 216 ? 158.414 120.305 118.880 1.00 34.79  ? 181 VAL D C   1 
ATOM   9585  O O   . VAL D 1 216 ? 159.467 119.998 119.452 1.00 41.13  ? 181 VAL D O   1 
ATOM   9586  C CB  . VAL D 1 216 ? 156.748 118.634 119.763 1.00 31.36  ? 181 VAL D CB  1 
ATOM   9587  C CG1 . VAL D 1 216 ? 156.053 119.717 120.572 1.00 26.73  ? 181 VAL D CG1 1 
ATOM   9588  C CG2 . VAL D 1 216 ? 155.769 117.541 119.379 1.00 30.25  ? 181 VAL D CG2 1 
ATOM   9589  N N   . ALA D 1 217 ? 158.108 121.555 118.539 1.00 32.91  ? 182 ALA D N   1 
ATOM   9590  C CA  . ALA D 1 217 ? 159.001 122.660 118.857 1.00 36.60  ? 182 ALA D CA  1 
ATOM   9591  C C   . ALA D 1 217 ? 159.218 122.751 120.362 1.00 46.65  ? 182 ALA D C   1 
ATOM   9592  O O   . ALA D 1 217 ? 158.322 122.461 121.160 1.00 46.05  ? 182 ALA D O   1 
ATOM   9593  C CB  . ALA D 1 217 ? 158.433 123.976 118.325 1.00 31.22  ? 182 ALA D CB  1 
ATOM   9594  N N   . GLU D 1 218 ? 160.436 123.145 120.747 1.00 50.28  ? 183 GLU D N   1 
ATOM   9595  C CA  . GLU D 1 218 ? 160.803 123.147 122.161 1.00 53.90  ? 183 GLU D CA  1 
ATOM   9596  C C   . GLU D 1 218 ? 159.877 124.042 122.974 1.00 52.37  ? 183 GLU D C   1 
ATOM   9597  O O   . GLU D 1 218 ? 159.475 123.685 124.087 1.00 53.58  ? 183 GLU D O   1 
ATOM   9598  C CB  . GLU D 1 218 ? 162.257 123.590 122.316 1.00 61.87  ? 183 GLU D CB  1 
ATOM   9599  C CG  . GLU D 1 218 ? 163.255 122.673 121.627 1.00 68.80  ? 183 GLU D CG  1 
ATOM   9600  C CD  . GLU D 1 218 ? 164.677 123.196 121.695 1.00 82.86  ? 183 GLU D CD  1 
ATOM   9601  O OE1 . GLU D 1 218 ? 164.944 124.095 122.519 1.00 82.47  ? 183 GLU D OE1 1 
ATOM   9602  O OE2 . GLU D 1 218 ? 165.528 122.706 120.923 1.00 86.91  ? 183 GLU D OE2 1 
ATOM   9603  N N   . ASP D 1 219 ? 159.529 125.208 122.438 1.00 52.69  ? 184 ASP D N   1 
ATOM   9604  C CA  . ASP D 1 219 ? 158.609 126.126 123.094 1.00 53.54  ? 184 ASP D CA  1 
ATOM   9605  C C   . ASP D 1 219 ? 157.163 125.889 122.681 1.00 51.05  ? 184 ASP D C   1 
ATOM   9606  O O   . ASP D 1 219 ? 156.303 126.730 122.961 1.00 53.65  ? 184 ASP D O   1 
ATOM   9607  C CB  . ASP D 1 219 ? 159.006 127.574 122.794 1.00 58.27  ? 184 ASP D CB  1 
ATOM   9608  C CG  . ASP D 1 219 ? 160.332 127.956 123.421 1.00 64.20  ? 184 ASP D CG  1 
ATOM   9609  O OD1 . ASP D 1 219 ? 160.954 127.093 124.075 1.00 61.69  ? 184 ASP D OD1 1 
ATOM   9610  O OD2 . ASP D 1 219 ? 160.756 129.120 123.256 1.00 68.94  ? 184 ASP D OD2 1 
ATOM   9611  N N   . GLY D 1 220 ? 156.878 124.766 122.023 1.00 47.99  ? 185 GLY D N   1 
ATOM   9612  C CA  . GLY D 1 220 ? 155.566 124.517 121.460 1.00 38.28  ? 185 GLY D CA  1 
ATOM   9613  C C   . GLY D 1 220 ? 154.497 124.044 122.419 1.00 34.36  ? 185 GLY D C   1 
ATOM   9614  O O   . GLY D 1 220 ? 153.344 123.910 122.004 1.00 30.35  ? 185 GLY D O   1 
ATOM   9615  N N   . SER D 1 221 ? 154.825 123.784 123.681 1.00 36.99  ? 186 SER D N   1 
ATOM   9616  C CA  . SER D 1 221 ? 153.810 123.303 124.611 1.00 34.58  ? 186 SER D CA  1 
ATOM   9617  C C   . SER D 1 221 ? 153.031 124.497 125.142 1.00 33.12  ? 186 SER D C   1 
ATOM   9618  O O   . SER D 1 221 ? 153.547 125.278 125.948 1.00 35.02  ? 186 SER D O   1 
ATOM   9619  C CB  . SER D 1 221 ? 154.454 122.514 125.747 1.00 39.29  ? 186 SER D CB  1 
ATOM   9620  O OG  . SER D 1 221 ? 153.487 122.116 126.703 1.00 33.95  ? 186 SER D OG  1 
ATOM   9621  N N   . ARG D 1 222 ? 151.789 124.641 124.688 1.00 29.89  ? 187 ARG D N   1 
ATOM   9622  C CA  . ARG D 1 222 ? 150.896 125.712 125.114 1.00 28.57  ? 187 ARG D CA  1 
ATOM   9623  C C   . ARG D 1 222 ? 149.757 125.168 125.970 1.00 27.39  ? 187 ARG D C   1 
ATOM   9624  O O   . ARG D 1 222 ? 148.600 125.567 125.828 1.00 24.91  ? 187 ARG D O   1 
ATOM   9625  C CB  . ARG D 1 222 ? 150.381 126.498 123.912 1.00 25.21  ? 187 ARG D CB  1 
ATOM   9626  C CG  . ARG D 1 222 ? 151.305 127.663 123.579 1.00 26.29  ? 187 ARG D CG  1 
ATOM   9627  C CD  . ARG D 1 222 ? 151.171 128.194 122.166 1.00 26.67  ? 187 ARG D CD  1 
ATOM   9628  N NE  . ARG D 1 222 ? 152.244 129.143 121.889 1.00 32.60  ? 187 ARG D NE  1 
ATOM   9629  C CZ  . ARG D 1 222 ? 152.529 129.641 120.694 1.00 42.55  ? 187 ARG D CZ  1 
ATOM   9630  N NH1 . ARG D 1 222 ? 151.830 129.310 119.621 1.00 46.59  ? 187 ARG D NH1 1 
ATOM   9631  N NH2 . ARG D 1 222 ? 153.544 130.491 120.571 1.00 43.23  ? 187 ARG D NH2 1 
ATOM   9632  N N   . LEU D 1 223 ? 150.085 124.248 126.871 1.00 32.44  ? 188 LEU D N   1 
ATOM   9633  C CA  . LEU D 1 223 ? 149.114 123.585 127.726 1.00 32.19  ? 188 LEU D CA  1 
ATOM   9634  C C   . LEU D 1 223 ? 149.143 124.192 129.121 1.00 29.43  ? 188 LEU D C   1 
ATOM   9635  O O   . LEU D 1 223 ? 150.212 124.498 129.657 1.00 28.09  ? 188 LEU D O   1 
ATOM   9636  C CB  . LEU D 1 223 ? 149.397 122.084 127.802 1.00 29.81  ? 188 LEU D CB  1 
ATOM   9637  C CG  . LEU D 1 223 ? 149.323 121.339 126.472 1.00 23.37  ? 188 LEU D CG  1 
ATOM   9638  C CD1 . LEU D 1 223 ? 149.830 119.919 126.616 1.00 23.93  ? 188 LEU D CD1 1 
ATOM   9639  C CD2 . LEU D 1 223 ? 147.895 121.344 125.974 1.00 21.39  ? 188 LEU D CD2 1 
ATOM   9640  N N   . ASN D 1 224 ? 147.958 124.366 129.701 1.00 27.45  ? 189 ASN D N   1 
ATOM   9641  C CA  . ASN D 1 224 ? 147.824 124.882 131.057 1.00 27.06  ? 189 ASN D CA  1 
ATOM   9642  C C   . ASN D 1 224 ? 147.704 123.764 132.086 1.00 31.33  ? 189 ASN D C   1 
ATOM   9643  O O   . ASN D 1 224 ? 148.408 123.776 133.101 1.00 35.68  ? 189 ASN D O   1 
ATOM   9644  C CB  . ASN D 1 224 ? 146.610 125.809 131.148 1.00 27.58  ? 189 ASN D CB  1 
ATOM   9645  C CG  . ASN D 1 224 ? 146.670 126.947 130.155 1.00 34.44  ? 189 ASN D CG  1 
ATOM   9646  O OD1 . ASN D 1 224 ? 147.033 126.755 128.996 1.00 36.09  ? 189 ASN D OD1 1 
ATOM   9647  N ND2 . ASN D 1 224 ? 146.311 128.142 130.604 1.00 43.76  ? 189 ASN D ND2 1 
ATOM   9648  N N   . GLN D 1 225 ? 146.825 122.793 131.841 1.00 31.04  ? 190 GLN D N   1 
ATOM   9649  C CA  . GLN D 1 225 ? 146.511 121.758 132.816 1.00 27.74  ? 190 GLN D CA  1 
ATOM   9650  C C   . GLN D 1 225 ? 147.076 120.399 132.440 1.00 25.61  ? 190 GLN D C   1 
ATOM   9651  O O   . GLN D 1 225 ? 146.722 119.400 133.071 1.00 27.51  ? 190 GLN D O   1 
ATOM   9652  C CB  . GLN D 1 225 ? 144.998 121.641 132.984 1.00 26.89  ? 190 GLN D CB  1 
ATOM   9653  C CG  . GLN D 1 225 ? 144.246 121.676 131.663 1.00 26.79  ? 190 GLN D CG  1 
ATOM   9654  C CD  . GLN D 1 225 ? 142.748 121.556 131.837 1.00 39.58  ? 190 GLN D CD  1 
ATOM   9655  O OE1 . GLN D 1 225 ? 142.264 121.138 132.889 1.00 45.43  ? 190 GLN D OE1 1 
ATOM   9656  N NE2 . GLN D 1 225 ? 142.003 121.922 130.801 1.00 37.86  ? 190 GLN D NE2 1 
ATOM   9657  N N   . TYR D 1 226 ? 147.947 120.330 131.440 1.00 22.45  ? 191 TYR D N   1 
ATOM   9658  C CA  . TYR D 1 226 ? 148.515 119.064 131.015 1.00 21.56  ? 191 TYR D CA  1 
ATOM   9659  C C   . TYR D 1 226 ? 150.025 119.187 130.896 1.00 23.25  ? 191 TYR D C   1 
ATOM   9660  O O   . TYR D 1 226 ? 150.577 120.283 130.767 1.00 26.77  ? 191 TYR D O   1 
ATOM   9661  C CB  . TYR D 1 226 ? 147.921 118.608 129.676 1.00 21.04  ? 191 TYR D CB  1 
ATOM   9662  C CG  . TYR D 1 226 ? 146.463 118.223 129.752 1.00 20.79  ? 191 TYR D CG  1 
ATOM   9663  C CD1 . TYR D 1 226 ? 146.078 116.978 130.227 1.00 22.78  ? 191 TYR D CD1 1 
ATOM   9664  C CD2 . TYR D 1 226 ? 145.471 119.107 129.357 1.00 21.56  ? 191 TYR D CD2 1 
ATOM   9665  C CE1 . TYR D 1 226 ? 144.748 116.623 130.302 1.00 23.90  ? 191 TYR D CE1 1 
ATOM   9666  C CE2 . TYR D 1 226 ? 144.137 118.761 129.428 1.00 24.60  ? 191 TYR D CE2 1 
ATOM   9667  C CZ  . TYR D 1 226 ? 143.781 117.518 129.902 1.00 25.52  ? 191 TYR D CZ  1 
ATOM   9668  O OH  . TYR D 1 226 ? 142.453 117.169 129.975 1.00 26.11  ? 191 TYR D OH  1 
ATOM   9669  N N   . ASP D 1 227 ? 150.688 118.038 130.944 1.00 24.46  ? 192 ASP D N   1 
ATOM   9670  C CA  . ASP D 1 227 ? 152.094 117.917 130.600 1.00 29.14  ? 192 ASP D CA  1 
ATOM   9671  C C   . ASP D 1 227 ? 152.196 117.005 129.390 1.00 29.74  ? 192 ASP D C   1 
ATOM   9672  O O   . ASP D 1 227 ? 151.695 115.877 129.421 1.00 31.15  ? 192 ASP D O   1 
ATOM   9673  C CB  . ASP D 1 227 ? 152.908 117.342 131.761 1.00 36.69  ? 192 ASP D CB  1 
ATOM   9674  C CG  . ASP D 1 227 ? 153.012 118.295 132.931 1.00 41.35  ? 192 ASP D CG  1 
ATOM   9675  O OD1 . ASP D 1 227 ? 153.290 119.490 132.700 1.00 41.40  ? 192 ASP D OD1 1 
ATOM   9676  O OD2 . ASP D 1 227 ? 152.818 117.850 134.082 1.00 41.67  ? 192 ASP D OD2 1 
ATOM   9677  N N   . LEU D 1 228 ? 152.836 117.486 128.330 1.00 29.43  ? 193 LEU D N   1 
ATOM   9678  C CA  . LEU D 1 228 ? 153.049 116.649 127.154 1.00 28.29  ? 193 LEU D CA  1 
ATOM   9679  C C   . LEU D 1 228 ? 154.198 115.702 127.474 1.00 29.66  ? 193 LEU D C   1 
ATOM   9680  O O   . LEU D 1 228 ? 155.373 116.038 127.323 1.00 33.67  ? 193 LEU D O   1 
ATOM   9681  C CB  . LEU D 1 228 ? 153.339 117.505 125.928 1.00 27.11  ? 193 LEU D CB  1 
ATOM   9682  C CG  . LEU D 1 228 ? 153.556 116.773 124.606 1.00 24.53  ? 193 LEU D CG  1 
ATOM   9683  C CD1 . LEU D 1 228 ? 152.426 115.795 124.352 1.00 21.50  ? 193 LEU D CD1 1 
ATOM   9684  C CD2 . LEU D 1 228 ? 153.670 117.769 123.467 1.00 30.03  ? 193 LEU D CD2 1 
ATOM   9685  N N   . LEU D 1 229 ? 153.849 114.497 127.932 1.00 26.53  ? 194 LEU D N   1 
ATOM   9686  C CA  . LEU D 1 229 ? 154.874 113.527 128.305 1.00 26.59  ? 194 LEU D CA  1 
ATOM   9687  C C   . LEU D 1 229 ? 155.688 113.100 127.093 1.00 32.44  ? 194 LEU D C   1 
ATOM   9688  O O   . LEU D 1 229 ? 156.918 112.996 127.163 1.00 38.35  ? 194 LEU D O   1 
ATOM   9689  C CB  . LEU D 1 229 ? 154.234 112.314 128.977 1.00 23.37  ? 194 LEU D CB  1 
ATOM   9690  C CG  . LEU D 1 229 ? 153.300 112.609 130.148 1.00 27.25  ? 194 LEU D CG  1 
ATOM   9691  C CD1 . LEU D 1 229 ? 152.778 111.316 130.751 1.00 27.09  ? 194 LEU D CD1 1 
ATOM   9692  C CD2 . LEU D 1 229 ? 154.010 113.448 131.194 1.00 28.92  ? 194 LEU D CD2 1 
ATOM   9693  N N   . GLY D 1 230 ? 155.016 112.845 125.978 1.00 30.20  ? 195 GLY D N   1 
ATOM   9694  C CA  . GLY D 1 230 ? 155.689 112.346 124.796 1.00 31.04  ? 195 GLY D CA  1 
ATOM   9695  C C   . GLY D 1 230 ? 154.667 111.969 123.745 1.00 28.94  ? 195 GLY D C   1 
ATOM   9696  O O   . GLY D 1 230 ? 153.510 112.384 123.812 1.00 27.39  ? 195 GLY D O   1 
ATOM   9697  N N   . GLN D 1 231 ? 155.116 111.184 122.773 1.00 33.12  ? 196 GLN D N   1 
ATOM   9698  C CA  . GLN D 1 231 ? 154.267 110.822 121.652 1.00 29.07  ? 196 GLN D CA  1 
ATOM   9699  C C   . GLN D 1 231 ? 154.716 109.476 121.111 1.00 32.07  ? 196 GLN D C   1 
ATOM   9700  O O   . GLN D 1 231 ? 155.894 109.116 121.192 1.00 40.01  ? 196 GLN D O   1 
ATOM   9701  C CB  . GLN D 1 231 ? 154.290 111.880 120.542 1.00 26.47  ? 196 GLN D CB  1 
ATOM   9702  C CG  . GLN D 1 231 ? 155.570 111.914 119.727 1.00 29.04  ? 196 GLN D CG  1 
ATOM   9703  C CD  . GLN D 1 231 ? 155.997 113.322 119.379 1.00 35.11  ? 196 GLN D CD  1 
ATOM   9704  O OE1 . GLN D 1 231 ? 155.553 114.288 119.998 1.00 37.65  ? 196 GLN D OE1 1 
ATOM   9705  N NE2 . GLN D 1 231 ? 156.859 113.448 118.378 1.00 39.71  ? 196 GLN D NE2 1 
ATOM   9706  N N   . THR D 1 232 ? 153.759 108.727 120.574 1.00 27.74  ? 197 THR D N   1 
ATOM   9707  C CA  . THR D 1 232 ? 154.031 107.477 119.883 1.00 29.91  ? 197 THR D CA  1 
ATOM   9708  C C   . THR D 1 232 ? 153.416 107.572 118.500 1.00 28.45  ? 197 THR D C   1 
ATOM   9709  O O   . THR D 1 232 ? 152.249 107.950 118.361 1.00 30.52  ? 197 THR D O   1 
ATOM   9710  C CB  . THR D 1 232 ? 153.467 106.265 120.633 1.00 33.11  ? 197 THR D CB  1 
ATOM   9711  O OG1 . THR D 1 232 ? 152.045 106.387 120.746 1.00 36.78  ? 197 THR D OG1 1 
ATOM   9712  C CG2 . THR D 1 232 ? 154.083 106.157 122.019 1.00 35.68  ? 197 THR D CG2 1 
ATOM   9713  N N   . VAL D 1 233 ? 154.198 107.229 117.485 1.00 31.57  ? 198 VAL D N   1 
ATOM   9714  C CA  . VAL D 1 233 ? 153.789 107.353 116.094 1.00 34.43  ? 198 VAL D CA  1 
ATOM   9715  C C   . VAL D 1 233 ? 153.653 105.957 115.505 1.00 41.32  ? 198 VAL D C   1 
ATOM   9716  O O   . VAL D 1 233 ? 154.588 105.151 115.575 1.00 46.73  ? 198 VAL D O   1 
ATOM   9717  C CB  . VAL D 1 233 ? 154.800 108.194 115.298 1.00 34.89  ? 198 VAL D CB  1 
ATOM   9718  C CG1 . VAL D 1 233 ? 154.496 108.122 113.835 1.00 31.67  ? 198 VAL D CG1 1 
ATOM   9719  C CG2 . VAL D 1 233 ? 154.779 109.636 115.777 1.00 32.67  ? 198 VAL D CG2 1 
ATOM   9720  N N   . ASP D 1 234 ? 152.488 105.676 114.926 1.00 35.70  ? 199 ASP D N   1 
ATOM   9721  C CA  . ASP D 1 234 ? 152.169 104.354 114.412 1.00 33.40  ? 199 ASP D CA  1 
ATOM   9722  C C   . ASP D 1 234 ? 151.485 104.506 113.061 1.00 32.28  ? 199 ASP D C   1 
ATOM   9723  O O   . ASP D 1 234 ? 151.133 105.610 112.639 1.00 34.44  ? 199 ASP D O   1 
ATOM   9724  C CB  . ASP D 1 234 ? 151.283 103.578 115.395 1.00 36.86  ? 199 ASP D CB  1 
ATOM   9725  C CG  . ASP D 1 234 ? 151.307 102.081 115.151 1.00 56.68  ? 199 ASP D CG  1 
ATOM   9726  O OD1 . ASP D 1 234 ? 152.218 101.607 114.439 1.00 57.87  ? 199 ASP D OD1 1 
ATOM   9727  O OD2 . ASP D 1 234 ? 150.419 101.377 115.677 1.00 60.79  ? 199 ASP D OD2 1 
ATOM   9728  N N   . SER D 1 235 ? 151.303 103.379 112.378 1.00 33.81  ? 200 SER D N   1 
ATOM   9729  C CA  . SER D 1 235 ? 150.524 103.338 111.151 1.00 32.85  ? 200 SER D CA  1 
ATOM   9730  C C   . SER D 1 235 ? 149.829 101.990 111.055 1.00 37.03  ? 200 SER D C   1 
ATOM   9731  O O   . SER D 1 235 ? 150.300 100.993 111.607 1.00 44.27  ? 200 SER D O   1 
ATOM   9732  C CB  . SER D 1 235 ? 151.400 103.572 109.916 1.00 32.65  ? 200 SER D CB  1 
ATOM   9733  O OG  . SER D 1 235 ? 152.324 102.514 109.740 1.00 42.69  ? 200 SER D OG  1 
ATOM   9734  N N   . GLY D 1 236 ? 148.703 101.969 110.356 1.00 35.78  ? 201 GLY D N   1 
ATOM   9735  C CA  . GLY D 1 236 ? 147.944 100.742 110.245 1.00 36.04  ? 201 GLY D CA  1 
ATOM   9736  C C   . GLY D 1 236 ? 146.857 100.861 109.204 1.00 34.85  ? 201 GLY D C   1 
ATOM   9737  O O   . GLY D 1 236 ? 146.808 101.821 108.433 1.00 38.68  ? 201 GLY D O   1 
ATOM   9738  N N   . ILE D 1 237 ? 145.978 99.864  109.195 1.00 35.10  ? 202 ILE D N   1 
ATOM   9739  C CA  . ILE D 1 237 ? 144.877 99.780  108.245 1.00 38.13  ? 202 ILE D CA  1 
ATOM   9740  C C   . ILE D 1 237 ? 143.570 99.853  109.019 1.00 44.18  ? 202 ILE D C   1 
ATOM   9741  O O   . ILE D 1 237 ? 143.407 99.169  110.036 1.00 47.42  ? 202 ILE D O   1 
ATOM   9742  C CB  . ILE D 1 237 ? 144.945 98.486  107.414 1.00 37.59  ? 202 ILE D CB  1 
ATOM   9743  C CG1 . ILE D 1 237 ? 146.267 98.408  106.649 1.00 39.95  ? 202 ILE D CG1 1 
ATOM   9744  C CG2 . ILE D 1 237 ? 143.771 98.405  106.455 1.00 43.48  ? 202 ILE D CG2 1 
ATOM   9745  C CD1 . ILE D 1 237 ? 146.493 99.562  105.705 1.00 40.29  ? 202 ILE D CD1 1 
ATOM   9746  N N   . VAL D 1 238 ? 142.646 100.682 108.543 1.00 44.61  ? 203 VAL D N   1 
ATOM   9747  C CA  . VAL D 1 238 ? 141.308 100.791 109.110 1.00 45.41  ? 203 VAL D CA  1 
ATOM   9748  C C   . VAL D 1 238 ? 140.302 100.456 108.019 1.00 48.72  ? 203 VAL D C   1 
ATOM   9749  O O   . VAL D 1 238 ? 140.381 100.992 106.908 1.00 43.83  ? 203 VAL D O   1 
ATOM   9750  C CB  . VAL D 1 238 ? 141.047 102.188 109.701 1.00 42.98  ? 203 VAL D CB  1 
ATOM   9751  C CG1 . VAL D 1 238 ? 139.576 102.358 110.035 1.00 48.18  ? 203 VAL D CG1 1 
ATOM   9752  C CG2 . VAL D 1 238 ? 141.886 102.388 110.951 1.00 42.44  ? 203 VAL D CG2 1 
ATOM   9753  N N   . GLN D 1 239 ? 139.363 99.573  108.339 1.00 55.99  ? 204 GLN D N   1 
ATOM   9754  C CA  . GLN D 1 239 ? 138.354 99.113  107.396 1.00 57.57  ? 204 GLN D CA  1 
ATOM   9755  C C   . GLN D 1 239 ? 137.028 99.801  107.685 1.00 58.20  ? 204 GLN D C   1 
ATOM   9756  O O   . GLN D 1 239 ? 136.596 99.870  108.840 1.00 55.45  ? 204 GLN D O   1 
ATOM   9757  C CB  . GLN D 1 239 ? 138.191 97.595  107.474 1.00 60.25  ? 204 GLN D CB  1 
ATOM   9758  C CG  . GLN D 1 239 ? 137.205 97.026  106.470 1.00 65.95  ? 204 GLN D CG  1 
ATOM   9759  C CD  . GLN D 1 239 ? 137.312 95.522  106.343 1.00 76.15  ? 204 GLN D CD  1 
ATOM   9760  O OE1 . GLN D 1 239 ? 138.404 94.978  106.182 1.00 78.02  ? 204 GLN D OE1 1 
ATOM   9761  N NE2 . GLN D 1 239 ? 136.176 94.840  106.418 1.00 77.41  ? 204 GLN D NE2 1 
ATOM   9762  N N   . SER D 1 240 ? 136.385 100.303 106.633 1.00 57.91  ? 205 SER D N   1 
ATOM   9763  C CA  . SER D 1 240 ? 135.080 100.936 106.765 1.00 59.42  ? 205 SER D CA  1 
ATOM   9764  C C   . SER D 1 240 ? 134.127 100.403 105.705 1.00 58.70  ? 205 SER D C   1 
ATOM   9765  O O   . SER D 1 240 ? 134.446 99.435  105.008 1.00 58.36  ? 205 SER D O   1 
ATOM   9766  C CB  . SER D 1 240 ? 135.205 102.456 106.654 1.00 54.97  ? 205 SER D CB  1 
ATOM   9767  O OG  . SER D 1 240 ? 135.621 102.834 105.353 1.00 51.45  ? 205 SER D OG  1 
ATOM   9768  N N   . SER D 1 241 ? 132.953 101.024 105.578 1.00 60.32  ? 206 SER D N   1 
ATOM   9769  C CA  . SER D 1 241 ? 131.946 100.518 104.653 1.00 62.33  ? 206 SER D CA  1 
ATOM   9770  C C   . SER D 1 241 ? 132.353 100.679 103.195 1.00 59.58  ? 206 SER D C   1 
ATOM   9771  O O   . SER D 1 241 ? 131.792 99.995  102.332 1.00 57.77  ? 206 SER D O   1 
ATOM   9772  C CB  . SER D 1 241 ? 130.610 101.218 104.900 1.00 67.89  ? 206 SER D CB  1 
ATOM   9773  O OG  . SER D 1 241 ? 130.768 102.625 104.925 1.00 69.92  ? 206 SER D OG  1 
ATOM   9774  N N   . THR D 1 242 ? 133.303 101.566 102.894 1.00 55.39  ? 207 THR D N   1 
ATOM   9775  C CA  . THR D 1 242 ? 133.689 101.819 101.513 1.00 53.67  ? 207 THR D CA  1 
ATOM   9776  C C   . THR D 1 242 ? 134.948 101.075 101.088 1.00 52.80  ? 207 THR D C   1 
ATOM   9777  O O   . THR D 1 242 ? 135.193 100.948 99.883  1.00 51.10  ? 207 THR D O   1 
ATOM   9778  C CB  . THR D 1 242 ? 133.896 103.321 101.285 1.00 51.94  ? 207 THR D CB  1 
ATOM   9779  O OG1 . THR D 1 242 ? 134.909 103.806 102.174 1.00 53.15  ? 207 THR D OG1 1 
ATOM   9780  C CG2 . THR D 1 242 ? 132.604 104.078 101.544 1.00 52.43  ? 207 THR D CG2 1 
ATOM   9781  N N   . GLY D 1 243 ? 135.741 100.591 102.029 1.00 51.00  ? 208 GLY D N   1 
ATOM   9782  C CA  . GLY D 1 243 ? 136.936 99.840  101.709 1.00 47.01  ? 208 GLY D CA  1 
ATOM   9783  C C   . GLY D 1 243 ? 137.962 99.981  102.816 1.00 50.19  ? 208 GLY D C   1 
ATOM   9784  O O   . GLY D 1 243 ? 137.700 100.566 103.863 1.00 50.90  ? 208 GLY D O   1 
ATOM   9785  N N   . GLU D 1 244 ? 139.140 99.416  102.561 1.00 48.69  ? 209 GLU D N   1 
ATOM   9786  C CA  . GLU D 1 244 ? 140.266 99.511  103.481 1.00 48.93  ? 209 GLU D CA  1 
ATOM   9787  C C   . GLU D 1 244 ? 141.115 100.728 103.136 1.00 45.27  ? 209 GLU D C   1 
ATOM   9788  O O   . GLU D 1 244 ? 141.447 100.950 101.968 1.00 44.24  ? 209 GLU D O   1 
ATOM   9789  C CB  . GLU D 1 244 ? 141.113 98.240  103.436 1.00 55.16  ? 209 GLU D CB  1 
ATOM   9790  C CG  . GLU D 1 244 ? 140.348 96.981  103.804 1.00 64.58  ? 209 GLU D CG  1 
ATOM   9791  C CD  . GLU D 1 244 ? 141.242 95.761  103.891 1.00 72.01  ? 209 GLU D CD  1 
ATOM   9792  O OE1 . GLU D 1 244 ? 142.457 95.897  103.642 1.00 66.41  ? 209 GLU D OE1 1 
ATOM   9793  O OE2 . GLU D 1 244 ? 140.730 94.668  104.212 1.00 74.01  ? 209 GLU D OE2 1 
ATOM   9794  N N   . TYR D 1 245 ? 141.464 101.512 104.153 1.00 44.48  ? 210 TYR D N   1 
ATOM   9795  C CA  . TYR D 1 245 ? 142.243 102.726 103.970 1.00 38.79  ? 210 TYR D CA  1 
ATOM   9796  C C   . TYR D 1 245 ? 143.454 102.696 104.890 1.00 38.35  ? 210 TYR D C   1 
ATOM   9797  O O   . TYR D 1 245 ? 143.405 102.125 105.982 1.00 37.41  ? 210 TYR D O   1 
ATOM   9798  C CB  . TYR D 1 245 ? 141.411 103.981 104.277 1.00 37.74  ? 210 TYR D CB  1 
ATOM   9799  C CG  . TYR D 1 245 ? 140.230 104.197 103.360 1.00 38.17  ? 210 TYR D CG  1 
ATOM   9800  C CD1 . TYR D 1 245 ? 139.040 103.513 103.561 1.00 40.03  ? 210 TYR D CD1 1 
ATOM   9801  C CD2 . TYR D 1 245 ? 140.297 105.094 102.307 1.00 36.99  ? 210 TYR D CD2 1 
ATOM   9802  C CE1 . TYR D 1 245 ? 137.957 103.706 102.734 1.00 37.71  ? 210 TYR D CE1 1 
ATOM   9803  C CE2 . TYR D 1 245 ? 139.216 105.295 101.473 1.00 36.96  ? 210 TYR D CE2 1 
ATOM   9804  C CZ  . TYR D 1 245 ? 138.049 104.598 101.691 1.00 36.37  ? 210 TYR D CZ  1 
ATOM   9805  O OH  . TYR D 1 245 ? 136.966 104.793 100.866 1.00 37.61  ? 210 TYR D OH  1 
ATOM   9806  N N   . VAL D 1 246 ? 144.542 103.318 104.445 1.00 39.37  ? 211 VAL D N   1 
ATOM   9807  C CA  . VAL D 1 246 ? 145.716 103.470 105.295 1.00 36.19  ? 211 VAL D CA  1 
ATOM   9808  C C   . VAL D 1 246 ? 145.495 104.653 106.223 1.00 30.01  ? 211 VAL D C   1 
ATOM   9809  O O   . VAL D 1 246 ? 144.968 105.695 105.815 1.00 31.94  ? 211 VAL D O   1 
ATOM   9810  C CB  . VAL D 1 246 ? 146.991 103.656 104.453 1.00 31.87  ? 211 VAL D CB  1 
ATOM   9811  C CG1 . VAL D 1 246 ? 148.202 103.825 105.355 1.00 23.18  ? 211 VAL D CG1 1 
ATOM   9812  C CG2 . VAL D 1 246 ? 147.193 102.474 103.540 1.00 39.00  ? 211 VAL D CG2 1 
ATOM   9813  N N   . VAL D 1 247 ? 145.904 104.499 107.478 1.00 25.99  ? 212 VAL D N   1 
ATOM   9814  C CA  . VAL D 1 247 ? 145.775 105.547 108.478 1.00 22.57  ? 212 VAL D CA  1 
ATOM   9815  C C   . VAL D 1 247 ? 147.129 105.745 109.134 1.00 26.12  ? 212 VAL D C   1 
ATOM   9816  O O   . VAL D 1 247 ? 147.753 104.779 109.585 1.00 32.92  ? 212 VAL D O   1 
ATOM   9817  C CB  . VAL D 1 247 ? 144.708 105.205 109.534 1.00 20.71  ? 212 VAL D CB  1 
ATOM   9818  C CG1 . VAL D 1 247 ? 144.513 106.369 110.483 1.00 18.53  ? 212 VAL D CG1 1 
ATOM   9819  C CG2 . VAL D 1 247 ? 143.401 104.859 108.857 1.00 27.81  ? 212 VAL D CG2 1 
ATOM   9820  N N   . MET D 1 248 ? 147.575 106.993 109.193 1.00 22.87  ? 213 MET D N   1 
ATOM   9821  C CA  . MET D 1 248 ? 148.746 107.369 109.968 1.00 19.78  ? 213 MET D CA  1 
ATOM   9822  C C   . MET D 1 248 ? 148.254 107.981 111.269 1.00 17.95  ? 213 MET D C   1 
ATOM   9823  O O   . MET D 1 248 ? 147.410 108.881 111.255 1.00 17.88  ? 213 MET D O   1 
ATOM   9824  C CB  . MET D 1 248 ? 149.621 108.355 109.198 1.00 18.82  ? 213 MET D CB  1 
ATOM   9825  C CG  . MET D 1 248 ? 149.745 108.012 107.730 1.00 20.98  ? 213 MET D CG  1 
ATOM   9826  S SD  . MET D 1 248 ? 150.506 106.409 107.426 1.00 35.17  ? 213 MET D SD  1 
ATOM   9827  C CE  . MET D 1 248 ? 152.132 106.672 108.108 1.00 30.84  ? 213 MET D CE  1 
ATOM   9828  N N   . THR D 1 249 ? 148.783 107.502 112.384 1.00 20.42  ? 214 THR D N   1 
ATOM   9829  C CA  . THR D 1 249 ? 148.290 107.906 113.688 1.00 21.18  ? 214 THR D CA  1 
ATOM   9830  C C   . THR D 1 249 ? 149.431 108.428 114.538 1.00 22.16  ? 214 THR D C   1 
ATOM   9831  O O   . THR D 1 249 ? 150.541 107.892 114.513 1.00 28.07  ? 214 THR D O   1 
ATOM   9832  C CB  . THR D 1 249 ? 147.607 106.744 114.421 1.00 24.60  ? 214 THR D CB  1 
ATOM   9833  O OG1 . THR D 1 249 ? 148.558 105.698 114.651 1.00 32.18  ? 214 THR D OG1 1 
ATOM   9834  C CG2 . THR D 1 249 ? 146.450 106.195 113.605 1.00 22.26  ? 214 THR D CG2 1 
ATOM   9835  N N   . THR D 1 250 ? 149.138 109.481 115.291 1.00 18.56  ? 215 THR D N   1 
ATOM   9836  C CA  . THR D 1 250 ? 150.056 110.041 116.266 1.00 20.81  ? 215 THR D CA  1 
ATOM   9837  C C   . THR D 1 250 ? 149.261 110.254 117.539 1.00 23.54  ? 215 THR D C   1 
ATOM   9838  O O   . THR D 1 250 ? 148.182 110.853 117.509 1.00 27.49  ? 215 THR D O   1 
ATOM   9839  C CB  . THR D 1 250 ? 150.663 111.361 115.779 1.00 22.30  ? 215 THR D CB  1 
ATOM   9840  O OG1 . THR D 1 250 ? 151.440 111.124 114.600 1.00 31.84  ? 215 THR D OG1 1 
ATOM   9841  C CG2 . THR D 1 250 ? 151.549 111.968 116.849 1.00 23.62  ? 215 THR D CG2 1 
ATOM   9842  N N   . HIS D 1 251 ? 149.784 109.752 118.647 1.00 24.10  ? 216 HIS D N   1 
ATOM   9843  C CA  . HIS D 1 251 ? 149.151 109.890 119.946 1.00 20.68  ? 216 HIS D CA  1 
ATOM   9844  C C   . HIS D 1 251 ? 150.013 110.777 120.826 1.00 22.76  ? 216 HIS D C   1 
ATOM   9845  O O   . HIS D 1 251 ? 151.210 110.521 120.986 1.00 26.22  ? 216 HIS D O   1 
ATOM   9846  C CB  . HIS D 1 251 ? 148.944 108.521 120.593 1.00 23.09  ? 216 HIS D CB  1 
ATOM   9847  C CG  . HIS D 1 251 ? 147.787 107.760 120.027 1.00 30.07  ? 216 HIS D CG  1 
ATOM   9848  N ND1 . HIS D 1 251 ? 147.928 106.840 119.010 1.00 27.36  ? 216 HIS D ND1 1 
ATOM   9849  C CD2 . HIS D 1 251 ? 146.467 107.787 120.329 1.00 32.98  ? 216 HIS D CD2 1 
ATOM   9850  C CE1 . HIS D 1 251 ? 146.746 106.333 118.711 1.00 27.65  ? 216 HIS D CE1 1 
ATOM   9851  N NE2 . HIS D 1 251 ? 145.843 106.889 119.497 1.00 32.45  ? 216 HIS D NE2 1 
ATOM   9852  N N   . PHE D 1 252 ? 149.406 111.810 121.393 1.00 22.82  ? 217 PHE D N   1 
ATOM   9853  C CA  . PHE D 1 252 ? 150.071 112.673 122.357 1.00 21.41  ? 217 PHE D CA  1 
ATOM   9854  C C   . PHE D 1 252 ? 149.580 112.274 123.737 1.00 21.73  ? 217 PHE D C   1 
ATOM   9855  O O   . PHE D 1 252 ? 148.379 112.341 124.015 1.00 24.83  ? 217 PHE D O   1 
ATOM   9856  C CB  . PHE D 1 252 ? 149.773 114.147 122.083 1.00 18.56  ? 217 PHE D CB  1 
ATOM   9857  C CG  . PHE D 1 252 ? 150.080 114.578 120.679 1.00 19.08  ? 217 PHE D CG  1 
ATOM   9858  C CD1 . PHE D 1 252 ? 151.361 114.961 120.322 1.00 21.43  ? 217 PHE D CD1 1 
ATOM   9859  C CD2 . PHE D 1 252 ? 149.087 114.606 119.716 1.00 20.25  ? 217 PHE D CD2 1 
ATOM   9860  C CE1 . PHE D 1 252 ? 151.644 115.357 119.032 1.00 22.23  ? 217 PHE D CE1 1 
ATOM   9861  C CE2 . PHE D 1 252 ? 149.366 115.003 118.425 1.00 21.07  ? 217 PHE D CE2 1 
ATOM   9862  C CZ  . PHE D 1 252 ? 150.646 115.377 118.083 1.00 22.31  ? 217 PHE D CZ  1 
ATOM   9863  N N   . HIS D 1 253 ? 150.504 111.862 124.598 1.00 20.94  ? 218 HIS D N   1 
ATOM   9864  C CA  . HIS D 1 253 ? 150.151 111.370 125.921 1.00 19.84  ? 218 HIS D CA  1 
ATOM   9865  C C   . HIS D 1 253 ? 150.167 112.550 126.879 1.00 22.33  ? 218 HIS D C   1 
ATOM   9866  O O   . HIS D 1 253 ? 151.221 113.140 127.138 1.00 26.46  ? 218 HIS D O   1 
ATOM   9867  C CB  . HIS D 1 253 ? 151.118 110.276 126.367 1.00 20.43  ? 218 HIS D CB  1 
ATOM   9868  C CG  . HIS D 1 253 ? 151.268 109.167 125.374 1.00 23.91  ? 218 HIS D CG  1 
ATOM   9869  N ND1 . HIS D 1 253 ? 150.342 108.155 125.243 1.00 29.06  ? 218 HIS D ND1 1 
ATOM   9870  C CD2 . HIS D 1 253 ? 152.233 108.914 124.459 1.00 27.04  ? 218 HIS D CD2 1 
ATOM   9871  C CE1 . HIS D 1 253 ? 150.731 107.325 124.292 1.00 29.62  ? 218 HIS D CE1 1 
ATOM   9872  N NE2 . HIS D 1 253 ? 151.875 107.763 123.800 1.00 28.07  ? 218 HIS D NE2 1 
ATOM   9873  N N   . LEU D 1 254 ? 148.998 112.889 127.404 1.00 21.81  ? 219 LEU D N   1 
ATOM   9874  C CA  . LEU D 1 254 ? 148.828 114.028 128.287 1.00 18.75  ? 219 LEU D CA  1 
ATOM   9875  C C   . LEU D 1 254 ? 148.565 113.535 129.699 1.00 20.03  ? 219 LEU D C   1 
ATOM   9876  O O   . LEU D 1 254 ? 147.908 112.509 129.898 1.00 24.57  ? 219 LEU D O   1 
ATOM   9877  C CB  . LEU D 1 254 ? 147.675 114.916 127.818 1.00 19.40  ? 219 LEU D CB  1 
ATOM   9878  C CG  . LEU D 1 254 ? 147.787 115.437 126.387 1.00 20.11  ? 219 LEU D CG  1 
ATOM   9879  C CD1 . LEU D 1 254 ? 146.604 116.320 126.043 1.00 21.24  ? 219 LEU D CD1 1 
ATOM   9880  C CD2 . LEU D 1 254 ? 149.087 116.193 126.204 1.00 21.97  ? 219 LEU D CD2 1 
ATOM   9881  N N   . LYS D 1 255 ? 149.081 114.271 130.673 1.00 21.55  ? 220 LYS D N   1 
ATOM   9882  C CA  . LYS D 1 255 ? 148.848 113.986 132.078 1.00 24.47  ? 220 LYS D CA  1 
ATOM   9883  C C   . LYS D 1 255 ? 148.380 115.270 132.737 1.00 23.81  ? 220 LYS D C   1 
ATOM   9884  O O   . LYS D 1 255 ? 149.041 116.305 132.621 1.00 27.43  ? 220 LYS D O   1 
ATOM   9885  C CB  . LYS D 1 255 ? 150.114 113.457 132.757 1.00 25.34  ? 220 LYS D CB  1 
ATOM   9886  C CG  . LYS D 1 255 ? 149.863 112.711 134.055 1.00 26.43  ? 220 LYS D CG  1 
ATOM   9887  C CD  . LYS D 1 255 ? 151.160 112.170 134.627 1.00 24.93  ? 220 LYS D CD  1 
ATOM   9888  C CE  . LYS D 1 255 ? 150.929 111.437 135.934 1.00 26.88  ? 220 LYS D CE  1 
ATOM   9889  N NZ  . LYS D 1 255 ? 152.210 110.972 136.533 1.00 27.80  ? 220 LYS D NZ  1 
ATOM   9890  N N   . ARG D 1 256 ? 147.249 115.201 133.427 1.00 19.46  ? 221 ARG D N   1 
ATOM   9891  C CA  . ARG D 1 256 ? 146.669 116.400 134.009 1.00 21.39  ? 221 ARG D CA  1 
ATOM   9892  C C   . ARG D 1 256 ? 147.470 116.826 135.230 1.00 24.64  ? 221 ARG D C   1 
ATOM   9893  O O   . ARG D 1 256 ? 147.801 116.004 136.089 1.00 28.28  ? 221 ARG D O   1 
ATOM   9894  C CB  . ARG D 1 256 ? 145.207 116.163 134.376 1.00 22.61  ? 221 ARG D CB  1 
ATOM   9895  C CG  . ARG D 1 256 ? 144.467 117.423 134.790 1.00 23.32  ? 221 ARG D CG  1 
ATOM   9896  C CD  . ARG D 1 256 ? 143.040 117.118 135.186 1.00 23.55  ? 221 ARG D CD  1 
ATOM   9897  N NE  . ARG D 1 256 ? 142.330 116.436 134.111 1.00 29.88  ? 221 ARG D NE  1 
ATOM   9898  C CZ  . ARG D 1 256 ? 141.696 117.052 133.123 1.00 34.11  ? 221 ARG D CZ  1 
ATOM   9899  N NH1 . ARG D 1 256 ? 141.648 118.371 133.048 1.00 34.77  ? 221 ARG D NH1 1 
ATOM   9900  N NH2 . ARG D 1 256 ? 141.094 116.325 132.186 1.00 32.49  ? 221 ARG D NH2 1 
ATOM   9901  N N   . LYS D 1 257 ? 147.784 118.116 135.302 1.00 22.82  ? 222 LYS D N   1 
ATOM   9902  C CA  . LYS D 1 257 ? 148.440 118.656 136.483 1.00 21.86  ? 222 LYS D CA  1 
ATOM   9903  C C   . LYS D 1 257 ? 147.442 118.748 137.626 1.00 21.93  ? 222 LYS D C   1 
ATOM   9904  O O   . LYS D 1 257 ? 146.330 119.255 137.458 1.00 22.66  ? 222 LYS D O   1 
ATOM   9905  C CB  . LYS D 1 257 ? 149.021 120.040 136.205 1.00 26.69  ? 222 LYS D CB  1 
ATOM   9906  C CG  . LYS D 1 257 ? 150.014 120.127 135.069 1.00 28.69  ? 222 LYS D CG  1 
ATOM   9907  C CD  . LYS D 1 257 ? 150.257 121.587 134.715 1.00 29.03  ? 222 LYS D CD  1 
ATOM   9908  C CE  . LYS D 1 257 ? 151.281 121.738 133.610 1.00 31.55  ? 222 LYS D CE  1 
ATOM   9909  N NZ  . LYS D 1 257 ? 151.335 123.135 133.097 1.00 32.58  ? 222 LYS D NZ  1 
ATOM   9910  N N   . ILE D 1 258 ? 147.842 118.248 138.794 1.00 22.04  ? 223 ILE D N   1 
ATOM   9911  C CA  . ILE D 1 258 ? 146.919 118.107 139.910 1.00 21.76  ? 223 ILE D CA  1 
ATOM   9912  C C   . ILE D 1 258 ? 147.103 119.208 140.942 1.00 21.99  ? 223 ILE D C   1 
ATOM   9913  O O   . ILE D 1 258 ? 146.231 119.380 141.809 1.00 22.94  ? 223 ILE D O   1 
ATOM   9914  C CB  . ILE D 1 258 ? 147.072 116.721 140.575 1.00 20.88  ? 223 ILE D CB  1 
ATOM   9915  C CG1 . ILE D 1 258 ? 145.888 116.418 141.493 1.00 21.55  ? 223 ILE D CG1 1 
ATOM   9916  C CG2 . ILE D 1 258 ? 148.380 116.637 141.342 1.00 18.42  ? 223 ILE D CG2 1 
ATOM   9917  C CD1 . ILE D 1 258 ? 145.930 115.045 142.096 1.00 26.56  ? 223 ILE D CD1 1 
ATOM   9918  N N   . GLY D 1 259 ? 148.199 119.971 140.872 1.00 20.60  ? 224 GLY D N   1 
ATOM   9919  C CA  . GLY D 1 259 ? 148.443 120.982 141.884 1.00 19.17  ? 224 GLY D CA  1 
ATOM   9920  C C   . GLY D 1 259 ? 147.315 121.985 141.989 1.00 17.06  ? 224 GLY D C   1 
ATOM   9921  O O   . GLY D 1 259 ? 147.075 122.546 143.060 1.00 21.39  ? 224 GLY D O   1 
ATOM   9922  N N   . TYR D 1 260 ? 146.617 122.239 140.879 1.00 14.28  ? 225 TYR D N   1 
ATOM   9923  C CA  . TYR D 1 260 ? 145.511 123.187 140.910 1.00 14.68  ? 225 TYR D CA  1 
ATOM   9924  C C   . TYR D 1 260 ? 144.364 122.641 141.746 1.00 17.20  ? 225 TYR D C   1 
ATOM   9925  O O   . TYR D 1 260 ? 143.829 123.335 142.618 1.00 19.36  ? 225 TYR D O   1 
ATOM   9926  C CB  . TYR D 1 260 ? 145.047 123.503 139.490 1.00 14.61  ? 225 TYR D CB  1 
ATOM   9927  C CG  . TYR D 1 260 ? 143.952 124.540 139.425 1.00 14.25  ? 225 TYR D CG  1 
ATOM   9928  C CD1 . TYR D 1 260 ? 144.170 125.833 139.877 1.00 15.21  ? 225 TYR D CD1 1 
ATOM   9929  C CD2 . TYR D 1 260 ? 142.706 124.231 138.900 1.00 15.56  ? 225 TYR D CD2 1 
ATOM   9930  C CE1 . TYR D 1 260 ? 143.177 126.787 139.815 1.00 16.20  ? 225 TYR D CE1 1 
ATOM   9931  C CE2 . TYR D 1 260 ? 141.705 125.179 138.834 1.00 17.32  ? 225 TYR D CE2 1 
ATOM   9932  C CZ  . TYR D 1 260 ? 141.946 126.455 139.293 1.00 19.31  ? 225 TYR D CZ  1 
ATOM   9933  O OH  . TYR D 1 260 ? 140.953 127.403 139.230 1.00 22.80  ? 225 TYR D OH  1 
ATOM   9934  N N   . PHE D 1 261 ? 143.972 121.390 141.491 1.00 19.20  ? 226 PHE D N   1 
ATOM   9935  C CA  . PHE D 1 261 ? 142.828 120.804 142.174 1.00 18.14  ? 226 PHE D CA  1 
ATOM   9936  C C   . PHE D 1 261 ? 143.151 120.429 143.609 1.00 16.78  ? 226 PHE D C   1 
ATOM   9937  O O   . PHE D 1 261 ? 142.231 120.265 144.416 1.00 18.23  ? 226 PHE D O   1 
ATOM   9938  C CB  . PHE D 1 261 ? 142.328 119.573 141.417 1.00 17.67  ? 226 PHE D CB  1 
ATOM   9939  C CG  . PHE D 1 261 ? 142.085 119.817 139.958 1.00 19.12  ? 226 PHE D CG  1 
ATOM   9940  C CD1 . PHE D 1 261 ? 140.859 120.280 139.518 1.00 21.31  ? 226 PHE D CD1 1 
ATOM   9941  C CD2 . PHE D 1 261 ? 143.079 119.583 139.026 1.00 20.19  ? 226 PHE D CD2 1 
ATOM   9942  C CE1 . PHE D 1 261 ? 140.630 120.507 138.177 1.00 25.40  ? 226 PHE D CE1 1 
ATOM   9943  C CE2 . PHE D 1 261 ? 142.855 119.811 137.684 1.00 20.06  ? 226 PHE D CE2 1 
ATOM   9944  C CZ  . PHE D 1 261 ? 141.629 120.273 137.260 1.00 23.57  ? 226 PHE D CZ  1 
ATOM   9945  N N   . VAL D 1 262 ? 144.435 120.290 143.942 1.00 15.35  ? 227 VAL D N   1 
ATOM   9946  C CA  . VAL D 1 262 ? 144.814 120.053 145.328 1.00 14.35  ? 227 VAL D CA  1 
ATOM   9947  C C   . VAL D 1 262 ? 144.552 121.299 146.161 1.00 14.95  ? 227 VAL D C   1 
ATOM   9948  O O   . VAL D 1 262 ? 144.038 121.217 147.281 1.00 17.18  ? 227 VAL D O   1 
ATOM   9949  C CB  . VAL D 1 262 ? 146.284 119.604 145.412 1.00 11.18  ? 227 VAL D CB  1 
ATOM   9950  C CG1 . VAL D 1 262 ? 146.755 119.586 146.855 1.00 11.14  ? 227 VAL D CG1 1 
ATOM   9951  C CG2 . VAL D 1 262 ? 146.447 118.230 144.790 1.00 13.56  ? 227 VAL D CG2 1 
ATOM   9952  N N   . ILE D 1 263 ? 144.862 122.473 145.614 1.00 14.08  ? 228 ILE D N   1 
ATOM   9953  C CA  . ILE D 1 263 ? 144.714 123.709 146.370 1.00 14.30  ? 228 ILE D CA  1 
ATOM   9954  C C   . ILE D 1 263 ? 143.320 124.312 146.218 1.00 16.96  ? 228 ILE D C   1 
ATOM   9955  O O   . ILE D 1 263 ? 142.860 125.025 147.122 1.00 21.66  ? 228 ILE D O   1 
ATOM   9956  C CB  . ILE D 1 263 ? 145.812 124.698 145.931 1.00 15.10  ? 228 ILE D CB  1 
ATOM   9957  C CG1 . ILE D 1 263 ? 147.166 124.258 146.488 1.00 18.48  ? 228 ILE D CG1 1 
ATOM   9958  C CG2 . ILE D 1 263 ? 145.515 126.121 146.373 1.00 14.44  ? 228 ILE D CG2 1 
ATOM   9959  C CD1 . ILE D 1 263 ? 148.319 125.123 146.038 1.00 24.21  ? 228 ILE D CD1 1 
ATOM   9960  N N   . GLN D 1 264 ? 142.606 123.992 145.139 1.00 16.51  ? 229 GLN D N   1 
ATOM   9961  C CA  . GLN D 1 264 ? 141.265 124.533 144.957 1.00 16.48  ? 229 GLN D CA  1 
ATOM   9962  C C   . GLN D 1 264 ? 140.190 123.629 145.544 1.00 18.05  ? 229 GLN D C   1 
ATOM   9963  O O   . GLN D 1 264 ? 139.223 124.123 146.135 1.00 19.49  ? 229 GLN D O   1 
ATOM   9964  C CB  . GLN D 1 264 ? 140.985 124.767 143.471 1.00 14.93  ? 229 GLN D CB  1 
ATOM   9965  C CG  . GLN D 1 264 ? 141.704 125.967 142.887 1.00 19.40  ? 229 GLN D CG  1 
ATOM   9966  C CD  . GLN D 1 264 ? 141.291 127.267 143.548 1.00 24.42  ? 229 GLN D CD  1 
ATOM   9967  O OE1 . GLN D 1 264 ? 140.107 127.508 143.781 1.00 26.16  ? 229 GLN D OE1 1 
ATOM   9968  N NE2 . GLN D 1 264 ? 142.267 128.111 143.859 1.00 24.62  ? 229 GLN D NE2 1 
ATOM   9969  N N   . THR D 1 265 ? 140.342 122.312 145.407 1.00 18.39  ? 230 THR D N   1 
ATOM   9970  C CA  . THR D 1 265 ? 139.288 121.378 145.786 1.00 18.25  ? 230 THR D CA  1 
ATOM   9971  C C   . THR D 1 265 ? 139.705 120.466 146.930 1.00 16.80  ? 230 THR D C   1 
ATOM   9972  O O   . THR D 1 265 ? 139.008 120.415 147.947 1.00 18.53  ? 230 THR D O   1 
ATOM   9973  C CB  . THR D 1 265 ? 138.860 120.547 144.571 1.00 21.52  ? 230 THR D CB  1 
ATOM   9974  O OG1 . THR D 1 265 ? 138.333 121.413 143.559 1.00 20.83  ? 230 THR D OG1 1 
ATOM   9975  C CG2 . THR D 1 265 ? 137.798 119.538 144.969 1.00 22.21  ? 230 THR D CG2 1 
ATOM   9976  N N   . TYR D 1 266 ? 140.814 119.736 146.797 1.00 16.78  ? 231 TYR D N   1 
ATOM   9977  C CA  . TYR D 1 266 ? 141.119 118.686 147.765 1.00 16.44  ? 231 TYR D CA  1 
ATOM   9978  C C   . TYR D 1 266 ? 141.429 119.258 149.143 1.00 16.76  ? 231 TYR D C   1 
ATOM   9979  O O   . TYR D 1 266 ? 140.866 118.810 150.147 1.00 20.07  ? 231 TYR D O   1 
ATOM   9980  C CB  . TYR D 1 266 ? 142.267 117.818 147.256 1.00 17.19  ? 231 TYR D CB  1 
ATOM   9981  C CG  . TYR D 1 266 ? 141.834 116.846 146.185 1.00 20.66  ? 231 TYR D CG  1 
ATOM   9982  C CD1 . TYR D 1 266 ? 141.060 115.743 146.506 1.00 24.14  ? 231 TYR D CD1 1 
ATOM   9983  C CD2 . TYR D 1 266 ? 142.186 117.035 144.857 1.00 21.94  ? 231 TYR D CD2 1 
ATOM   9984  C CE1 . TYR D 1 266 ? 140.654 114.852 145.543 1.00 24.37  ? 231 TYR D CE1 1 
ATOM   9985  C CE2 . TYR D 1 266 ? 141.783 116.145 143.882 1.00 24.54  ? 231 TYR D CE2 1 
ATOM   9986  C CZ  . TYR D 1 266 ? 141.017 115.055 144.233 1.00 23.64  ? 231 TYR D CZ  1 
ATOM   9987  O OH  . TYR D 1 266 ? 140.605 114.160 143.278 1.00 27.00  ? 231 TYR D OH  1 
ATOM   9988  N N   . LEU D 1 267 ? 142.332 120.237 149.219 1.00 13.55  ? 232 LEU D N   1 
ATOM   9989  C CA  . LEU D 1 267 ? 142.694 120.779 150.528 1.00 13.65  ? 232 LEU D CA  1 
ATOM   9990  C C   . LEU D 1 267 ? 141.525 121.465 151.224 1.00 16.24  ? 232 LEU D C   1 
ATOM   9991  O O   . LEU D 1 267 ? 141.322 121.213 152.424 1.00 18.47  ? 232 LEU D O   1 
ATOM   9992  C CB  . LEU D 1 267 ? 143.905 121.708 150.402 1.00 13.54  ? 232 LEU D CB  1 
ATOM   9993  C CG  . LEU D 1 267 ? 145.250 121.019 150.166 1.00 13.49  ? 232 LEU D CG  1 
ATOM   9994  C CD1 . LEU D 1 267 ? 146.363 122.045 150.031 1.00 12.39  ? 232 LEU D CD1 1 
ATOM   9995  C CD2 . LEU D 1 267 ? 145.552 120.034 151.283 1.00 10.75  ? 232 LEU D CD2 1 
ATOM   9996  N N   . PRO D 1 268 ? 140.746 122.344 150.576 1.00 14.32  ? 233 PRO D N   1 
ATOM   9997  C CA  . PRO D 1 268 ? 139.567 122.889 151.271 1.00 13.46  ? 233 PRO D CA  1 
ATOM   9998  C C   . PRO D 1 268 ? 138.602 121.819 151.747 1.00 12.02  ? 233 PRO D C   1 
ATOM   9999  O O   . PRO D 1 268 ? 138.042 121.940 152.843 1.00 13.02  ? 233 PRO D O   1 
ATOM   10000 C CB  . PRO D 1 268 ? 138.928 123.794 150.211 1.00 14.57  ? 233 PRO D CB  1 
ATOM   10001 C CG  . PRO D 1 268 ? 140.047 124.196 149.342 1.00 14.14  ? 233 PRO D CG  1 
ATOM   10002 C CD  . PRO D 1 268 ? 140.964 123.013 149.280 1.00 13.58  ? 233 PRO D CD  1 
ATOM   10003 N N   . CYS D 1 269 ? 138.386 120.771 150.947 1.00 12.92  ? 234 CYS D N   1 
ATOM   10004 C CA  . CYS D 1 269 ? 137.524 119.679 151.384 1.00 14.17  ? 234 CYS D CA  1 
ATOM   10005 C C   . CYS D 1 269 ? 138.114 118.945 152.579 1.00 14.64  ? 234 CYS D C   1 
ATOM   10006 O O   . CYS D 1 269 ? 137.396 118.615 153.529 1.00 18.17  ? 234 CYS D O   1 
ATOM   10007 C CB  . CYS D 1 269 ? 137.275 118.706 150.231 1.00 15.28  ? 234 CYS D CB  1 
ATOM   10008 S SG  . CYS D 1 269 ? 136.241 119.356 148.903 1.00 18.58  ? 234 CYS D SG  1 
ATOM   10009 N N   . ILE D 1 270 ? 139.420 118.670 152.547 1.00 13.39  ? 235 ILE D N   1 
ATOM   10010 C CA  . ILE D 1 270 ? 140.046 117.955 153.654 1.00 13.72  ? 235 ILE D CA  1 
ATOM   10011 C C   . ILE D 1 270 ? 140.027 118.796 154.923 1.00 14.48  ? 235 ILE D C   1 
ATOM   10012 O O   . ILE D 1 270 ? 139.765 118.284 156.017 1.00 14.58  ? 235 ILE D O   1 
ATOM   10013 C CB  . ILE D 1 270 ? 141.475 117.531 153.273 1.00 13.70  ? 235 ILE D CB  1 
ATOM   10014 C CG1 . ILE D 1 270 ? 141.437 116.430 152.213 1.00 12.82  ? 235 ILE D CG1 1 
ATOM   10015 C CG2 . ILE D 1 270 ? 142.241 117.060 154.496 1.00 14.24  ? 235 ILE D CG2 1 
ATOM   10016 C CD1 . ILE D 1 270 ? 142.780 116.138 151.596 1.00 17.44  ? 235 ILE D CD1 1 
ATOM   10017 N N   . MET D 1 271 ? 140.277 120.101 154.801 1.00 14.80  ? 236 MET D N   1 
ATOM   10018 C CA  . MET D 1 271 ? 140.294 120.946 155.990 1.00 14.90  ? 236 MET D CA  1 
ATOM   10019 C C   . MET D 1 271 ? 138.894 121.209 156.524 1.00 14.35  ? 236 MET D C   1 
ATOM   10020 O O   . MET D 1 271 ? 138.730 121.445 157.725 1.00 15.89  ? 236 MET D O   1 
ATOM   10021 C CB  . MET D 1 271 ? 141.009 122.260 155.691 1.00 16.53  ? 236 MET D CB  1 
ATOM   10022 C CG  . MET D 1 271 ? 142.517 122.170 155.815 1.00 24.52  ? 236 MET D CG  1 
ATOM   10023 S SD  . MET D 1 271 ? 143.325 123.752 155.542 1.00 46.66  ? 236 MET D SD  1 
ATOM   10024 C CE  . MET D 1 271 ? 143.080 123.913 153.782 1.00 19.80  ? 236 MET D CE  1 
ATOM   10025 N N   . THR D 1 272 ? 137.876 121.178 155.663 1.00 15.79  ? 237 THR D N   1 
ATOM   10026 C CA  . THR D 1 272 ? 136.511 121.317 156.160 1.00 12.99  ? 237 THR D CA  1 
ATOM   10027 C C   . THR D 1 272 ? 136.051 120.036 156.844 1.00 14.43  ? 237 THR D C   1 
ATOM   10028 O O   . THR D 1 272 ? 135.369 120.086 157.874 1.00 17.10  ? 237 THR D O   1 
ATOM   10029 C CB  . THR D 1 272 ? 135.564 121.692 155.024 1.00 10.91  ? 237 THR D CB  1 
ATOM   10030 O OG1 . THR D 1 272 ? 135.849 123.025 154.586 1.00 13.65  ? 237 THR D OG1 1 
ATOM   10031 C CG2 . THR D 1 272 ? 134.121 121.633 155.496 1.00 10.44  ? 237 THR D CG2 1 
ATOM   10032 N N   . VAL D 1 273 ? 136.434 118.879 156.298 1.00 14.19  ? 238 VAL D N   1 
ATOM   10033 C CA  . VAL D 1 273 ? 136.114 117.618 156.958 1.00 14.76  ? 238 VAL D CA  1 
ATOM   10034 C C   . VAL D 1 273 ? 136.823 117.538 158.300 1.00 16.60  ? 238 VAL D C   1 
ATOM   10035 O O   . VAL D 1 273 ? 136.238 117.103 159.299 1.00 19.74  ? 238 VAL D O   1 
ATOM   10036 C CB  . VAL D 1 273 ? 136.471 116.429 156.050 1.00 13.86  ? 238 VAL D CB  1 
ATOM   10037 C CG1 . VAL D 1 273 ? 136.391 115.128 156.825 1.00 15.36  ? 238 VAL D CG1 1 
ATOM   10038 C CG2 . VAL D 1 273 ? 135.535 116.387 154.868 1.00 13.69  ? 238 VAL D CG2 1 
ATOM   10039 N N   . ILE D 1 274 ? 138.093 117.946 158.346 1.00 14.71  ? 239 ILE D N   1 
ATOM   10040 C CA  . ILE D 1 274 ? 138.788 117.995 159.627 1.00 13.93  ? 239 ILE D CA  1 
ATOM   10041 C C   . ILE D 1 274 ? 138.081 118.970 160.555 1.00 15.63  ? 239 ILE D C   1 
ATOM   10042 O O   . ILE D 1 274 ? 137.897 118.697 161.748 1.00 19.72  ? 239 ILE D O   1 
ATOM   10043 C CB  . ILE D 1 274 ? 140.269 118.370 159.430 1.00 11.99  ? 239 ILE D CB  1 
ATOM   10044 C CG1 . ILE D 1 274 ? 141.018 117.250 158.709 1.00 14.11  ? 239 ILE D CG1 1 
ATOM   10045 C CG2 . ILE D 1 274 ? 140.929 118.674 160.763 1.00 11.03  ? 239 ILE D CG2 1 
ATOM   10046 C CD1 . ILE D 1 274 ? 142.411 117.637 158.276 1.00 13.32  ? 239 ILE D CD1 1 
ATOM   10047 N N   . LEU D 1 275 ? 137.655 120.115 160.016 1.00 14.51  ? 240 LEU D N   1 
ATOM   10048 C CA  . LEU D 1 275 ? 136.970 121.110 160.832 1.00 14.49  ? 240 LEU D CA  1 
ATOM   10049 C C   . LEU D 1 275 ? 135.655 120.564 161.368 1.00 16.72  ? 240 LEU D C   1 
ATOM   10050 O O   . LEU D 1 275 ? 135.296 120.815 162.523 1.00 19.77  ? 240 LEU D O   1 
ATOM   10051 C CB  . LEU D 1 275 ? 136.730 122.378 160.014 1.00 15.72  ? 240 LEU D CB  1 
ATOM   10052 C CG  . LEU D 1 275 ? 136.995 123.721 160.691 1.00 15.69  ? 240 LEU D CG  1 
ATOM   10053 C CD1 . LEU D 1 275 ? 138.266 123.658 161.517 1.00 16.79  ? 240 LEU D CD1 1 
ATOM   10054 C CD2 . LEU D 1 275 ? 137.089 124.817 159.646 1.00 11.47  ? 240 LEU D CD2 1 
ATOM   10055 N N   . SER D 1 276 ? 134.918 119.818 160.539 1.00 16.59  ? 241 SER D N   1 
ATOM   10056 C CA  . SER D 1 276 ? 133.665 119.230 161.001 1.00 16.59  ? 241 SER D CA  1 
ATOM   10057 C C   . SER D 1 276 ? 133.911 118.236 162.125 1.00 19.53  ? 241 SER D C   1 
ATOM   10058 O O   . SER D 1 276 ? 133.030 118.008 162.960 1.00 21.62  ? 241 SER D O   1 
ATOM   10059 C CB  . SER D 1 276 ? 132.935 118.559 159.839 1.00 12.35  ? 241 SER D CB  1 
ATOM   10060 O OG  . SER D 1 276 ? 133.703 117.499 159.301 1.00 13.20  ? 241 SER D OG  1 
ATOM   10061 N N   . GLN D 1 277 ? 135.101 117.642 162.160 1.00 20.11  ? 242 GLN D N   1 
ATOM   10062 C CA  . GLN D 1 277 ? 135.465 116.686 163.194 1.00 19.07  ? 242 GLN D CA  1 
ATOM   10063 C C   . GLN D 1 277 ? 136.039 117.378 164.417 1.00 20.11  ? 242 GLN D C   1 
ATOM   10064 O O   . GLN D 1 277 ? 136.015 116.811 165.514 1.00 27.57  ? 242 GLN D O   1 
ATOM   10065 C CB  . GLN D 1 277 ? 136.461 115.667 162.639 1.00 17.98  ? 242 GLN D CB  1 
ATOM   10066 C CG  . GLN D 1 277 ? 135.852 114.777 161.570 1.00 20.45  ? 242 GLN D CG  1 
ATOM   10067 C CD  . GLN D 1 277 ? 136.889 114.054 160.744 1.00 23.41  ? 242 GLN D CD  1 
ATOM   10068 O OE1 . GLN D 1 277 ? 136.576 113.481 159.702 1.00 23.17  ? 242 GLN D OE1 1 
ATOM   10069 N NE2 . GLN D 1 277 ? 138.133 114.075 161.204 1.00 26.23  ? 242 GLN D NE2 1 
ATOM   10070 N N   . VAL D 1 278 ? 136.563 118.594 164.240 1.00 19.29  ? 243 VAL D N   1 
ATOM   10071 C CA  . VAL D 1 278 ? 136.982 119.418 165.368 1.00 24.34  ? 243 VAL D CA  1 
ATOM   10072 C C   . VAL D 1 278 ? 135.818 119.647 166.325 1.00 28.29  ? 243 VAL D C   1 
ATOM   10073 O O   . VAL D 1 278 ? 136.020 119.889 167.522 1.00 29.54  ? 243 VAL D O   1 
ATOM   10074 C CB  . VAL D 1 278 ? 137.577 120.741 164.840 1.00 24.18  ? 243 VAL D CB  1 
ATOM   10075 C CG1 . VAL D 1 278 ? 137.812 121.718 165.953 1.00 20.48  ? 243 VAL D CG1 1 
ATOM   10076 C CG2 . VAL D 1 278 ? 138.883 120.479 164.111 1.00 20.85  ? 243 VAL D CG2 1 
ATOM   10077 N N   . SER D 1 279 ? 134.583 119.529 165.827 1.00 26.69  ? 244 SER D N   1 
ATOM   10078 C CA  . SER D 1 279 ? 133.412 119.696 166.680 1.00 26.67  ? 244 SER D CA  1 
ATOM   10079 C C   . SER D 1 279 ? 133.369 118.635 167.768 1.00 30.59  ? 244 SER D C   1 
ATOM   10080 O O   . SER D 1 279 ? 132.845 118.887 168.859 1.00 36.87  ? 244 SER D O   1 
ATOM   10081 C CB  . SER D 1 279 ? 132.137 119.650 165.838 1.00 27.99  ? 244 SER D CB  1 
ATOM   10082 O OG  . SER D 1 279 ? 130.983 119.730 166.656 1.00 29.68  ? 244 SER D OG  1 
ATOM   10083 N N   . PHE D 1 280 ? 133.904 117.445 167.486 1.00 28.89  ? 245 PHE D N   1 
ATOM   10084 C CA  . PHE D 1 280 ? 133.915 116.360 168.459 1.00 28.91  ? 245 PHE D CA  1 
ATOM   10085 C C   . PHE D 1 280 ? 134.661 116.731 169.732 1.00 31.97  ? 245 PHE D C   1 
ATOM   10086 O O   . PHE D 1 280 ? 134.421 116.117 170.776 1.00 38.14  ? 245 PHE D O   1 
ATOM   10087 C CB  . PHE D 1 280 ? 134.538 115.106 167.847 1.00 28.33  ? 245 PHE D CB  1 
ATOM   10088 C CG  . PHE D 1 280 ? 133.848 114.630 166.602 1.00 27.29  ? 245 PHE D CG  1 
ATOM   10089 C CD1 . PHE D 1 280 ? 132.498 114.859 166.408 1.00 27.25  ? 245 PHE D CD1 1 
ATOM   10090 C CD2 . PHE D 1 280 ? 134.552 113.956 165.624 1.00 28.09  ? 245 PHE D CD2 1 
ATOM   10091 C CE1 . PHE D 1 280 ? 131.866 114.422 165.263 1.00 25.02  ? 245 PHE D CE1 1 
ATOM   10092 C CE2 . PHE D 1 280 ? 133.925 113.519 164.477 1.00 26.45  ? 245 PHE D CE2 1 
ATOM   10093 C CZ  . PHE D 1 280 ? 132.582 113.751 164.297 1.00 24.70  ? 245 PHE D CZ  1 
ATOM   10094 N N   . TRP D 1 281 ? 135.560 117.711 169.673 1.00 27.88  ? 246 TRP D N   1 
ATOM   10095 C CA  . TRP D 1 281 ? 136.370 118.074 170.825 1.00 31.71  ? 246 TRP D CA  1 
ATOM   10096 C C   . TRP D 1 281 ? 135.741 119.183 171.658 1.00 33.22  ? 246 TRP D C   1 
ATOM   10097 O O   . TRP D 1 281 ? 136.275 119.519 172.719 1.00 35.53  ? 246 TRP D O   1 
ATOM   10098 C CB  . TRP D 1 281 ? 137.765 118.516 170.369 1.00 33.15  ? 246 TRP D CB  1 
ATOM   10099 C CG  . TRP D 1 281 ? 138.516 117.485 169.578 1.00 38.05  ? 246 TRP D CG  1 
ATOM   10100 C CD1 . TRP D 1 281 ? 138.340 117.175 168.259 1.00 37.52  ? 246 TRP D CD1 1 
ATOM   10101 C CD2 . TRP D 1 281 ? 139.567 116.634 170.050 1.00 43.24  ? 246 TRP D CD2 1 
ATOM   10102 N NE1 . TRP D 1 281 ? 139.213 116.184 167.884 1.00 38.17  ? 246 TRP D NE1 1 
ATOM   10103 C CE2 . TRP D 1 281 ? 139.977 115.834 168.965 1.00 43.50  ? 246 TRP D CE2 1 
ATOM   10104 C CE3 . TRP D 1 281 ? 140.199 116.470 171.286 1.00 49.32  ? 246 TRP D CE3 1 
ATOM   10105 C CZ2 . TRP D 1 281 ? 140.989 114.885 169.079 1.00 49.59  ? 246 TRP D CZ2 1 
ATOM   10106 C CZ3 . TRP D 1 281 ? 141.204 115.527 171.396 1.00 53.89  ? 246 TRP D CZ3 1 
ATOM   10107 C CH2 . TRP D 1 281 ? 141.588 114.747 170.300 1.00 52.96  ? 246 TRP D CH2 1 
ATOM   10108 N N   . LEU D 1 282 ? 134.630 119.758 171.205 1.00 34.11  ? 247 LEU D N   1 
ATOM   10109 C CA  . LEU D 1 282 ? 133.857 120.683 172.017 1.00 35.33  ? 247 LEU D CA  1 
ATOM   10110 C C   . LEU D 1 282 ? 133.030 119.927 173.052 1.00 36.26  ? 247 LEU D C   1 
ATOM   10111 O O   . LEU D 1 282 ? 132.707 118.748 172.888 1.00 36.84  ? 247 LEU D O   1 
ATOM   10112 C CB  . LEU D 1 282 ? 132.945 121.540 171.139 1.00 31.98  ? 247 LEU D CB  1 
ATOM   10113 C CG  . LEU D 1 282 ? 133.641 122.374 170.062 1.00 28.18  ? 247 LEU D CG  1 
ATOM   10114 C CD1 . LEU D 1 282 ? 132.619 123.064 169.182 1.00 30.78  ? 247 LEU D CD1 1 
ATOM   10115 C CD2 . LEU D 1 282 ? 134.583 123.388 170.687 1.00 23.35  ? 247 LEU D CD2 1 
ATOM   10116 N N   . ASN D 1 283 ? 132.691 120.621 174.134 1.00 40.85  ? 248 ASN D N   1 
ATOM   10117 C CA  . ASN D 1 283 ? 131.893 120.011 175.187 1.00 45.20  ? 248 ASN D CA  1 
ATOM   10118 C C   . ASN D 1 283 ? 130.461 119.785 174.715 1.00 50.43  ? 248 ASN D C   1 
ATOM   10119 O O   . ASN D 1 283 ? 129.924 120.540 173.901 1.00 51.89  ? 248 ASN D O   1 
ATOM   10120 C CB  . ASN D 1 283 ? 131.897 120.889 176.437 1.00 48.39  ? 248 ASN D CB  1 
ATOM   10121 C CG  . ASN D 1 283 ? 131.221 122.225 176.211 1.00 44.81  ? 248 ASN D CG  1 
ATOM   10122 O OD1 . ASN D 1 283 ? 130.038 122.391 176.502 1.00 46.90  ? 248 ASN D OD1 1 
ATOM   10123 N ND2 . ASN D 1 283 ? 131.971 123.188 175.689 1.00 38.21  ? 248 ASN D ND2 1 
ATOM   10124 N N   . ARG D 1 284 ? 129.844 118.721 175.233 1.00 53.44  ? 249 ARG D N   1 
ATOM   10125 C CA  . ARG D 1 284 ? 128.527 118.308 174.762 1.00 52.62  ? 249 ARG D CA  1 
ATOM   10126 C C   . ARG D 1 284 ? 127.415 119.258 175.186 1.00 53.28  ? 249 ARG D C   1 
ATOM   10127 O O   . ARG D 1 284 ? 126.306 119.157 174.653 1.00 54.34  ? 249 ARG D O   1 
ATOM   10128 C CB  . ARG D 1 284 ? 128.202 116.902 175.270 1.00 47.49  ? 249 ARG D CB  1 
ATOM   10129 C CG  . ARG D 1 284 ? 127.940 116.848 176.765 1.00 54.86  ? 249 ARG D CG  1 
ATOM   10130 C CD  . ARG D 1 284 ? 128.020 115.436 177.315 1.00 50.73  ? 249 ARG D CD  1 
ATOM   10131 N NE  . ARG D 1 284 ? 127.131 114.519 176.613 1.00 47.99  ? 249 ARG D NE  1 
ATOM   10132 C CZ  . ARG D 1 284 ? 127.015 113.229 176.896 1.00 51.51  ? 249 ARG D CZ  1 
ATOM   10133 N NH1 . ARG D 1 284 ? 127.717 112.668 177.866 1.00 57.62  ? 249 ARG D NH1 1 
ATOM   10134 N NH2 . ARG D 1 284 ? 126.171 112.484 176.189 1.00 50.08  ? 249 ARG D NH2 1 
ATOM   10135 N N   . GLU D 1 285 ? 127.676 120.171 176.119 1.00 48.71  ? 250 GLU D N   1 
ATOM   10136 C CA  . GLU D 1 285 ? 126.644 121.078 176.602 1.00 46.18  ? 250 GLU D CA  1 
ATOM   10137 C C   . GLU D 1 285 ? 126.476 122.323 175.744 1.00 47.02  ? 250 GLU D C   1 
ATOM   10138 O O   . GLU D 1 285 ? 125.497 123.053 175.930 1.00 54.76  ? 250 GLU D O   1 
ATOM   10139 C CB  . GLU D 1 285 ? 126.946 121.513 178.039 1.00 57.68  ? 250 GLU D CB  1 
ATOM   10140 C CG  . GLU D 1 285 ? 127.089 120.375 179.034 1.00 69.21  ? 250 GLU D CG  1 
ATOM   10141 C CD  . GLU D 1 285 ? 128.482 119.774 179.036 1.00 66.03  ? 250 GLU D CD  1 
ATOM   10142 O OE1 . GLU D 1 285 ? 129.444 120.500 178.705 1.00 53.56  ? 250 GLU D OE1 1 
ATOM   10143 O OE2 . GLU D 1 285 ? 128.619 118.581 179.376 1.00 70.07  ? 250 GLU D OE2 1 
ATOM   10144 N N   . SER D 1 286 ? 127.391 122.586 174.814 1.00 44.61  ? 251 SER D N   1 
ATOM   10145 C CA  . SER D 1 286 ? 127.268 123.745 173.931 1.00 39.47  ? 251 SER D CA  1 
ATOM   10146 C C   . SER D 1 286 ? 126.479 123.347 172.685 1.00 33.07  ? 251 SER D C   1 
ATOM   10147 O O   . SER D 1 286 ? 127.005 123.221 171.579 1.00 32.23  ? 251 SER D O   1 
ATOM   10148 C CB  . SER D 1 286 ? 128.644 124.297 173.580 1.00 36.92  ? 251 SER D CB  1 
ATOM   10149 O OG  . SER D 1 286 ? 129.470 123.295 173.017 1.00 42.35  ? 251 SER D OG  1 
ATOM   10150 N N   . VAL D 1 287 ? 125.178 123.138 172.896 1.00 32.94  ? 252 VAL D N   1 
ATOM   10151 C CA  . VAL D 1 287 ? 124.316 122.697 171.800 1.00 30.82  ? 252 VAL D CA  1 
ATOM   10152 C C   . VAL D 1 287 ? 124.234 123.737 170.688 1.00 31.33  ? 252 VAL D C   1 
ATOM   10153 O O   . VAL D 1 287 ? 124.393 123.364 169.514 1.00 32.71  ? 252 VAL D O   1 
ATOM   10154 C CB  . VAL D 1 287 ? 122.932 122.300 172.344 1.00 29.22  ? 252 VAL D CB  1 
ATOM   10155 C CG1 . VAL D 1 287 ? 122.073 121.722 171.235 1.00 31.44  ? 252 VAL D CG1 1 
ATOM   10156 C CG2 . VAL D 1 287 ? 123.079 121.317 173.491 1.00 33.13  ? 252 VAL D CG2 1 
ATOM   10157 N N   . PRO D 1 288 ? 123.975 125.026 170.961 1.00 31.67  ? 253 PRO D N   1 
ATOM   10158 C CA  . PRO D 1 288 ? 123.936 125.990 169.846 1.00 27.10  ? 253 PRO D CA  1 
ATOM   10159 C C   . PRO D 1 288 ? 125.241 126.056 169.072 1.00 25.63  ? 253 PRO D C   1 
ATOM   10160 O O   . PRO D 1 288 ? 125.221 126.168 167.840 1.00 23.46  ? 253 PRO D O   1 
ATOM   10161 C CB  . PRO D 1 288 ? 123.608 127.323 170.534 1.00 25.06  ? 253 PRO D CB  1 
ATOM   10162 C CG  . PRO D 1 288 ? 123.037 126.960 171.847 1.00 26.88  ? 253 PRO D CG  1 
ATOM   10163 C CD  . PRO D 1 288 ? 123.679 125.679 172.250 1.00 31.25  ? 253 PRO D CD  1 
ATOM   10164 N N   . ALA D 1 289 ? 126.380 126.000 169.768 1.00 27.23  ? 254 ALA D N   1 
ATOM   10165 C CA  . ALA D 1 289 ? 127.670 126.118 169.096 1.00 27.04  ? 254 ALA D CA  1 
ATOM   10166 C C   . ALA D 1 289 ? 127.950 124.909 168.213 1.00 27.58  ? 254 ALA D C   1 
ATOM   10167 O O   . ALA D 1 289 ? 128.387 125.054 167.067 1.00 28.66  ? 254 ALA D O   1 
ATOM   10168 C CB  . ALA D 1 289 ? 128.783 126.302 170.127 1.00 30.91  ? 254 ALA D CB  1 
ATOM   10169 N N   . ARG D 1 290 ? 127.702 123.703 168.730 1.00 27.54  ? 255 ARG D N   1 
ATOM   10170 C CA  . ARG D 1 290 ? 127.970 122.495 167.958 1.00 25.68  ? 255 ARG D CA  1 
ATOM   10171 C C   . ARG D 1 290 ? 126.936 122.260 166.868 1.00 26.74  ? 255 ARG D C   1 
ATOM   10172 O O   . ARG D 1 290 ? 127.241 121.588 165.878 1.00 27.32  ? 255 ARG D O   1 
ATOM   10173 C CB  . ARG D 1 290 ? 128.035 121.271 168.873 1.00 29.00  ? 255 ARG D CB  1 
ATOM   10174 C CG  . ARG D 1 290 ? 129.204 121.277 169.838 1.00 37.63  ? 255 ARG D CG  1 
ATOM   10175 C CD  . ARG D 1 290 ? 129.280 119.974 170.615 1.00 40.06  ? 255 ARG D CD  1 
ATOM   10176 N NE  . ARG D 1 290 ? 129.540 118.838 169.739 1.00 41.61  ? 255 ARG D NE  1 
ATOM   10177 C CZ  . ARG D 1 290 ? 129.871 117.626 170.161 1.00 40.36  ? 255 ARG D CZ  1 
ATOM   10178 N NH1 . ARG D 1 290 ? 130.023 117.360 171.447 1.00 44.74  ? 255 ARG D NH1 1 
ATOM   10179 N NH2 . ARG D 1 290 ? 130.067 116.659 169.270 1.00 32.77  ? 255 ARG D NH2 1 
ATOM   10180 N N   . THR D 1 291 ? 125.725 122.798 167.022 1.00 27.76  ? 256 THR D N   1 
ATOM   10181 C CA  . THR D 1 291 ? 124.765 122.757 165.926 1.00 23.38  ? 256 THR D CA  1 
ATOM   10182 C C   . THR D 1 291 ? 125.126 123.762 164.842 1.00 25.00  ? 256 THR D C   1 
ATOM   10183 O O   . THR D 1 291 ? 125.065 123.441 163.651 1.00 26.66  ? 256 THR D O   1 
ATOM   10184 C CB  . THR D 1 291 ? 123.354 123.017 166.447 1.00 19.94  ? 256 THR D CB  1 
ATOM   10185 O OG1 . THR D 1 291 ? 123.023 122.040 167.440 1.00 21.69  ? 256 THR D OG1 1 
ATOM   10186 C CG2 . THR D 1 291 ? 122.351 122.932 165.315 1.00 18.58  ? 256 THR D CG2 1 
ATOM   10187 N N   . VAL D 1 292 ? 125.529 124.973 165.228 1.00 24.15  ? 257 VAL D N   1 
ATOM   10188 C CA  . VAL D 1 292 ? 126.012 125.927 164.235 1.00 21.62  ? 257 VAL D CA  1 
ATOM   10189 C C   . VAL D 1 292 ? 127.272 125.393 163.568 1.00 21.41  ? 257 VAL D C   1 
ATOM   10190 O O   . VAL D 1 292 ? 127.439 125.499 162.346 1.00 23.34  ? 257 VAL D O   1 
ATOM   10191 C CB  . VAL D 1 292 ? 126.246 127.304 164.884 1.00 20.87  ? 257 VAL D CB  1 
ATOM   10192 C CG1 . VAL D 1 292 ? 127.082 128.186 163.974 1.00 24.91  ? 257 VAL D CG1 1 
ATOM   10193 C CG2 . VAL D 1 292 ? 124.916 127.969 165.195 1.00 18.85  ? 257 VAL D CG2 1 
ATOM   10194 N N   . PHE D 1 293 ? 128.177 124.812 164.358 1.00 20.22  ? 258 PHE D N   1 
ATOM   10195 C CA  . PHE D 1 293 ? 129.415 124.268 163.809 1.00 22.02  ? 258 PHE D CA  1 
ATOM   10196 C C   . PHE D 1 293 ? 129.121 123.192 162.768 1.00 21.31  ? 258 PHE D C   1 
ATOM   10197 O O   . PHE D 1 293 ? 129.613 123.256 161.636 1.00 19.74  ? 258 PHE D O   1 
ATOM   10198 C CB  . PHE D 1 293 ? 130.278 123.706 164.941 1.00 23.93  ? 258 PHE D CB  1 
ATOM   10199 C CG  . PHE D 1 293 ? 131.754 123.676 164.640 1.00 20.53  ? 258 PHE D CG  1 
ATOM   10200 C CD1 . PHE D 1 293 ? 132.223 123.372 163.374 1.00 17.49  ? 258 PHE D CD1 1 
ATOM   10201 C CD2 . PHE D 1 293 ? 132.674 123.949 165.637 1.00 21.98  ? 258 PHE D CD2 1 
ATOM   10202 C CE1 . PHE D 1 293 ? 133.575 123.347 163.110 1.00 18.13  ? 258 PHE D CE1 1 
ATOM   10203 C CE2 . PHE D 1 293 ? 134.028 123.925 165.379 1.00 21.68  ? 258 PHE D CE2 1 
ATOM   10204 C CZ  . PHE D 1 293 ? 134.479 123.624 164.114 1.00 20.70  ? 258 PHE D CZ  1 
ATOM   10205 N N   . GLY D 1 294 ? 128.306 122.201 163.133 1.00 20.16  ? 259 GLY D N   1 
ATOM   10206 C CA  . GLY D 1 294 ? 128.054 121.091 162.227 1.00 17.02  ? 259 GLY D CA  1 
ATOM   10207 C C   . GLY D 1 294 ? 127.277 121.482 160.985 1.00 15.60  ? 259 GLY D C   1 
ATOM   10208 O O   . GLY D 1 294 ? 127.559 120.989 159.890 1.00 13.66  ? 259 GLY D O   1 
ATOM   10209 N N   . VAL D 1 295 ? 126.294 122.374 161.128 1.00 17.36  ? 260 VAL D N   1 
ATOM   10210 C CA  . VAL D 1 295 ? 125.428 122.692 159.997 1.00 16.88  ? 260 VAL D CA  1 
ATOM   10211 C C   . VAL D 1 295 ? 126.162 123.567 158.989 1.00 16.75  ? 260 VAL D C   1 
ATOM   10212 O O   . VAL D 1 295 ? 125.989 123.416 157.774 1.00 17.03  ? 260 VAL D O   1 
ATOM   10213 C CB  . VAL D 1 295 ? 124.121 123.353 160.470 1.00 12.15  ? 260 VAL D CB  1 
ATOM   10214 C CG1 . VAL D 1 295 ? 123.268 123.709 159.281 1.00 11.25  ? 260 VAL D CG1 1 
ATOM   10215 C CG2 . VAL D 1 295 ? 123.350 122.420 161.369 1.00 13.61  ? 260 VAL D CG2 1 
ATOM   10216 N N   . THR D 1 296 ? 127.000 124.487 159.470 1.00 15.57  ? 261 THR D N   1 
ATOM   10217 C CA  . THR D 1 296 ? 127.711 125.368 158.552 1.00 15.02  ? 261 THR D CA  1 
ATOM   10218 C C   . THR D 1 296 ? 128.820 124.632 157.809 1.00 16.85  ? 261 THR D C   1 
ATOM   10219 O O   . THR D 1 296 ? 129.167 125.015 156.686 1.00 18.40  ? 261 THR D O   1 
ATOM   10220 C CB  . THR D 1 296 ? 128.268 126.570 159.311 1.00 14.50  ? 261 THR D CB  1 
ATOM   10221 O OG1 . THR D 1 296 ? 127.224 127.160 160.094 1.00 14.63  ? 261 THR D OG1 1 
ATOM   10222 C CG2 . THR D 1 296 ? 128.795 127.615 158.346 1.00 12.23  ? 261 THR D CG2 1 
ATOM   10223 N N   . THR D 1 297 ? 129.376 123.568 158.397 1.00 15.20  ? 262 THR D N   1 
ATOM   10224 C CA  . THR D 1 297 ? 130.322 122.748 157.647 1.00 13.42  ? 262 THR D CA  1 
ATOM   10225 C C   . THR D 1 297 ? 129.618 121.978 156.538 1.00 14.41  ? 262 THR D C   1 
ATOM   10226 O O   . THR D 1 297 ? 130.228 121.681 155.505 1.00 13.69  ? 262 THR D O   1 
ATOM   10227 C CB  . THR D 1 297 ? 131.062 121.789 158.576 1.00 12.97  ? 262 THR D CB  1 
ATOM   10228 O OG1 . THR D 1 297 ? 130.116 120.979 159.283 1.00 16.72  ? 262 THR D OG1 1 
ATOM   10229 C CG2 . THR D 1 297 ? 131.919 122.561 159.565 1.00 12.35  ? 262 THR D CG2 1 
ATOM   10230 N N   . VAL D 1 298 ? 128.343 121.643 156.737 1.00 14.57  ? 263 VAL D N   1 
ATOM   10231 C CA  . VAL D 1 298 ? 127.556 121.037 155.670 1.00 14.00  ? 263 VAL D CA  1 
ATOM   10232 C C   . VAL D 1 298 ? 127.344 122.046 154.553 1.00 14.91  ? 263 VAL D C   1 
ATOM   10233 O O   . VAL D 1 298 ? 127.444 121.716 153.365 1.00 18.13  ? 263 VAL D O   1 
ATOM   10234 C CB  . VAL D 1 298 ? 126.216 120.510 156.215 1.00 13.03  ? 263 VAL D CB  1 
ATOM   10235 C CG1 . VAL D 1 298 ? 125.357 119.994 155.080 1.00 13.44  ? 263 VAL D CG1 1 
ATOM   10236 C CG2 . VAL D 1 298 ? 126.441 119.425 157.247 1.00 13.20  ? 263 VAL D CG2 1 
ATOM   10237 N N   . LEU D 1 299 ? 127.047 123.293 154.920 1.00 12.07  ? 264 LEU D N   1 
ATOM   10238 C CA  . LEU D 1 299 ? 126.897 124.354 153.932 1.00 12.09  ? 264 LEU D CA  1 
ATOM   10239 C C   . LEU D 1 299 ? 128.222 124.642 153.236 1.00 14.99  ? 264 LEU D C   1 
ATOM   10240 O O   . LEU D 1 299 ? 128.247 124.910 152.029 1.00 16.54  ? 264 LEU D O   1 
ATOM   10241 C CB  . LEU D 1 299 ? 126.338 125.610 154.599 1.00 10.91  ? 264 LEU D CB  1 
ATOM   10242 C CG  . LEU D 1 299 ? 126.142 126.846 153.723 1.00 10.93  ? 264 LEU D CG  1 
ATOM   10243 C CD1 . LEU D 1 299 ? 125.296 126.508 152.511 1.00 9.24   ? 264 LEU D CD1 1 
ATOM   10244 C CD2 . LEU D 1 299 ? 125.485 127.949 154.529 1.00 11.16  ? 264 LEU D CD2 1 
ATOM   10245 N N   . THR D 1 300 ? 129.332 124.606 153.980 1.00 13.83  ? 265 THR D N   1 
ATOM   10246 C CA  . THR D 1 300 ? 130.640 124.793 153.358 1.00 11.03  ? 265 THR D CA  1 
ATOM   10247 C C   . THR D 1 300 ? 130.922 123.691 152.342 1.00 14.36  ? 265 THR D C   1 
ATOM   10248 O O   . THR D 1 300 ? 131.432 123.964 151.249 1.00 17.09  ? 265 THR D O   1 
ATOM   10249 C CB  . THR D 1 300 ? 131.733 124.840 154.423 1.00 9.92   ? 265 THR D CB  1 
ATOM   10250 O OG1 . THR D 1 300 ? 131.425 125.864 155.375 1.00 12.00  ? 265 THR D OG1 1 
ATOM   10251 C CG2 . THR D 1 300 ? 133.074 125.145 153.789 1.00 9.82   ? 265 THR D CG2 1 
ATOM   10252 N N   . MET D 1 301 ? 130.597 122.438 152.680 1.00 13.37  ? 266 MET D N   1 
ATOM   10253 C CA  . MET D 1 301 ? 130.751 121.358 151.709 1.00 13.27  ? 266 MET D CA  1 
ATOM   10254 C C   . MET D 1 301 ? 129.870 121.586 150.495 1.00 15.64  ? 266 MET D C   1 
ATOM   10255 O O   . MET D 1 301 ? 130.288 121.330 149.361 1.00 17.80  ? 266 MET D O   1 
ATOM   10256 C CB  . MET D 1 301 ? 130.411 120.013 152.357 1.00 15.11  ? 266 MET D CB  1 
ATOM   10257 C CG  . MET D 1 301 ? 131.516 119.279 153.111 1.00 17.46  ? 266 MET D CG  1 
ATOM   10258 S SD  . MET D 1 301 ? 132.991 118.912 152.124 1.00 26.72  ? 266 MET D SD  1 
ATOM   10259 C CE  . MET D 1 301 ? 133.967 120.398 152.209 1.00 21.09  ? 266 MET D CE  1 
ATOM   10260 N N   . THR D 1 302 ? 128.646 122.066 150.710 1.00 14.62  ? 267 THR D N   1 
ATOM   10261 C CA  . THR D 1 302 ? 127.775 122.340 149.578 1.00 14.58  ? 267 THR D CA  1 
ATOM   10262 C C   . THR D 1 302 ? 128.365 123.411 148.670 1.00 18.38  ? 267 THR D C   1 
ATOM   10263 O O   . THR D 1 302 ? 128.343 123.273 147.442 1.00 23.57  ? 267 THR D O   1 
ATOM   10264 C CB  . THR D 1 302 ? 126.395 122.760 150.078 1.00 13.38  ? 267 THR D CB  1 
ATOM   10265 O OG1 . THR D 1 302 ? 125.863 121.736 150.926 1.00 14.29  ? 267 THR D OG1 1 
ATOM   10266 C CG2 . THR D 1 302 ? 125.461 122.981 148.914 1.00 15.02  ? 267 THR D CG2 1 
ATOM   10267 N N   . THR D 1 303 ? 128.900 124.489 149.254 1.00 16.18  ? 268 THR D N   1 
ATOM   10268 C CA  . THR D 1 303 ? 129.549 125.513 148.441 1.00 14.94  ? 268 THR D CA  1 
ATOM   10269 C C   . THR D 1 303 ? 130.764 124.963 147.703 1.00 16.20  ? 268 THR D C   1 
ATOM   10270 O O   . THR D 1 303 ? 130.949 125.232 146.510 1.00 19.23  ? 268 THR D O   1 
ATOM   10271 C CB  . THR D 1 303 ? 129.950 126.699 149.316 1.00 14.23  ? 268 THR D CB  1 
ATOM   10272 O OG1 . THR D 1 303 ? 128.799 127.188 150.014 1.00 16.59  ? 268 THR D OG1 1 
ATOM   10273 C CG2 . THR D 1 303 ? 130.520 127.816 148.462 1.00 14.92  ? 268 THR D CG2 1 
ATOM   10274 N N   . LEU D 1 304 ? 131.604 124.189 148.396 1.00 15.98  ? 269 LEU D N   1 
ATOM   10275 C CA  . LEU D 1 304 ? 132.763 123.587 147.743 1.00 18.22  ? 269 LEU D CA  1 
ATOM   10276 C C   . LEU D 1 304 ? 132.349 122.578 146.681 1.00 26.26  ? 269 LEU D C   1 
ATOM   10277 O O   . LEU D 1 304 ? 132.920 122.555 145.586 1.00 33.40  ? 269 LEU D O   1 
ATOM   10278 C CB  . LEU D 1 304 ? 133.697 122.956 148.775 1.00 14.24  ? 269 LEU D CB  1 
ATOM   10279 C CG  . LEU D 1 304 ? 134.407 124.006 149.632 1.00 13.08  ? 269 LEU D CG  1 
ATOM   10280 C CD1 . LEU D 1 304 ? 135.090 123.397 150.835 1.00 11.41  ? 269 LEU D CD1 1 
ATOM   10281 C CD2 . LEU D 1 304 ? 135.408 124.772 148.788 1.00 19.91  ? 269 LEU D CD2 1 
ATOM   10282 N N   . SER D 1 305 ? 131.356 121.737 146.984 1.00 21.30  ? 270 SER D N   1 
ATOM   10283 C CA  . SER D 1 305 ? 130.948 120.714 146.027 1.00 18.22  ? 270 SER D CA  1 
ATOM   10284 C C   . SER D 1 305 ? 130.378 121.343 144.765 1.00 22.67  ? 270 SER D C   1 
ATOM   10285 O O   . SER D 1 305 ? 130.653 120.880 143.653 1.00 26.71  ? 270 SER D O   1 
ATOM   10286 C CB  . SER D 1 305 ? 129.928 119.773 146.665 1.00 16.90  ? 270 SER D CB  1 
ATOM   10287 O OG  . SER D 1 305 ? 129.300 118.965 145.687 1.00 24.67  ? 270 SER D OG  1 
ATOM   10288 N N   . ILE D 1 306 ? 129.572 122.394 144.919 1.00 21.67  ? 271 ILE D N   1 
ATOM   10289 C CA  . ILE D 1 306 ? 128.960 123.035 143.760 1.00 24.81  ? 271 ILE D CA  1 
ATOM   10290 C C   . ILE D 1 306 ? 130.037 123.631 142.864 1.00 29.04  ? 271 ILE D C   1 
ATOM   10291 O O   . ILE D 1 306 ? 130.022 123.453 141.641 1.00 37.31  ? 271 ILE D O   1 
ATOM   10292 C CB  . ILE D 1 306 ? 127.936 124.092 144.209 1.00 22.95  ? 271 ILE D CB  1 
ATOM   10293 C CG1 . ILE D 1 306 ? 126.678 123.404 144.738 1.00 18.81  ? 271 ILE D CG1 1 
ATOM   10294 C CG2 . ILE D 1 306 ? 127.592 125.019 143.061 1.00 24.20  ? 271 ILE D CG2 1 
ATOM   10295 C CD1 . ILE D 1 306 ? 125.801 124.297 145.569 1.00 16.91  ? 271 ILE D CD1 1 
ATOM   10296 N N   . SER D 1 307 ? 130.994 124.346 143.462 1.00 26.65  ? 272 SER D N   1 
ATOM   10297 C CA  . SER D 1 307 ? 132.027 124.990 142.659 1.00 32.12  ? 272 SER D CA  1 
ATOM   10298 C C   . SER D 1 307 ? 132.983 123.956 142.081 1.00 37.09  ? 272 SER D C   1 
ATOM   10299 O O   . SER D 1 307 ? 133.478 124.119 140.960 1.00 39.18  ? 272 SER D O   1 
ATOM   10300 C CB  . SER D 1 307 ? 132.786 126.014 143.501 1.00 32.62  ? 272 SER D CB  1 
ATOM   10301 O OG  . SER D 1 307 ? 133.848 126.592 142.763 1.00 39.80  ? 272 SER D OG  1 
ATOM   10302 N N   . ALA D 1 308 ? 133.265 122.894 142.841 1.00 34.63  ? 273 ALA D N   1 
ATOM   10303 C CA  . ALA D 1 308 ? 134.206 121.878 142.384 1.00 34.59  ? 273 ALA D CA  1 
ATOM   10304 C C   . ALA D 1 308 ? 133.715 121.213 141.109 1.00 41.55  ? 273 ALA D C   1 
ATOM   10305 O O   . ALA D 1 308 ? 134.522 120.789 140.275 1.00 44.39  ? 273 ALA D O   1 
ATOM   10306 C CB  . ALA D 1 308 ? 134.440 120.833 143.472 1.00 30.65  ? 273 ALA D CB  1 
ATOM   10307 N N   . ARG D 1 309 ? 132.397 121.112 140.943 1.00 42.87  ? 274 ARG D N   1 
ATOM   10308 C CA  . ARG D 1 309 ? 131.816 120.470 139.776 1.00 48.74  ? 274 ARG D CA  1 
ATOM   10309 C C   . ARG D 1 309 ? 131.679 121.421 138.597 1.00 49.68  ? 274 ARG D C   1 
ATOM   10310 O O   . ARG D 1 309 ? 131.475 120.961 137.468 1.00 52.22  ? 274 ARG D O   1 
ATOM   10311 C CB  . ARG D 1 309 ? 130.439 119.895 140.131 1.00 46.56  ? 274 ARG D CB  1 
ATOM   10312 C CG  . ARG D 1 309 ? 129.936 118.819 139.184 1.00 56.27  ? 274 ARG D CG  1 
ATOM   10313 C CD  . ARG D 1 309 ? 130.943 117.693 139.065 1.00 53.37  ? 274 ARG D CD  1 
ATOM   10314 N NE  . ARG D 1 309 ? 130.385 116.496 138.448 1.00 47.87  ? 274 ARG D NE  1 
ATOM   10315 C CZ  . ARG D 1 309 ? 130.203 116.342 137.143 1.00 53.60  ? 274 ARG D CZ  1 
ATOM   10316 N NH1 . ARG D 1 309 ? 130.469 117.315 136.288 1.00 58.17  ? 274 ARG D NH1 1 
ATOM   10317 N NH2 . ARG D 1 309 ? 129.737 115.184 136.686 1.00 57.49  ? 274 ARG D NH2 1 
ATOM   10318 N N   . ASN D 1 310 ? 131.789 122.731 138.829 1.00 44.62  ? 275 ASN D N   1 
ATOM   10319 C CA  . ASN D 1 310 ? 131.804 123.671 137.714 1.00 48.76  ? 275 ASN D CA  1 
ATOM   10320 C C   . ASN D 1 310 ? 133.042 123.470 136.851 1.00 52.21  ? 275 ASN D C   1 
ATOM   10321 O O   . ASN D 1 310 ? 132.966 123.537 135.619 1.00 48.93  ? 275 ASN D O   1 
ATOM   10322 C CB  . ASN D 1 310 ? 131.736 125.108 138.228 1.00 45.18  ? 275 ASN D CB  1 
ATOM   10323 C CG  . ASN D 1 310 ? 130.393 125.443 138.838 1.00 43.67  ? 275 ASN D CG  1 
ATOM   10324 O OD1 . ASN D 1 310 ? 129.502 124.599 138.902 1.00 43.02  ? 275 ASN D OD1 1 
ATOM   10325 N ND2 . ASN D 1 310 ? 130.235 126.685 139.280 1.00 43.49  ? 275 ASN D ND2 1 
ATOM   10326 N N   . SER D 1 311 ? 134.195 123.238 137.485 1.00 52.14  ? 276 SER D N   1 
ATOM   10327 C CA  . SER D 1 311 ? 135.413 122.970 136.729 1.00 53.92  ? 276 SER D CA  1 
ATOM   10328 C C   . SER D 1 311 ? 135.286 121.693 135.909 1.00 52.94  ? 276 SER D C   1 
ATOM   10329 O O   . SER D 1 311 ? 135.746 121.635 134.762 1.00 57.44  ? 276 SER D O   1 
ATOM   10330 C CB  . SER D 1 311 ? 136.609 122.882 137.677 1.00 54.13  ? 276 SER D CB  1 
ATOM   10331 O OG  . SER D 1 311 ? 137.795 122.557 136.975 1.00 58.04  ? 276 SER D OG  1 
ATOM   10332 N N   . LEU D 1 312 ? 134.688 120.655 136.486 1.00 48.71  ? 277 LEU D N   1 
ATOM   10333 C CA  . LEU D 1 312 ? 134.502 119.409 135.759 1.00 50.90  ? 277 LEU D CA  1 
ATOM   10334 C C   . LEU D 1 312 ? 133.659 119.650 134.509 1.00 56.93  ? 277 LEU D C   1 
ATOM   10335 O O   . LEU D 1 312 ? 132.724 120.458 134.537 1.00 60.06  ? 277 LEU D O   1 
ATOM   10336 C CB  . LEU D 1 312 ? 133.828 118.362 136.650 1.00 54.38  ? 277 LEU D CB  1 
ATOM   10337 C CG  . LEU D 1 312 ? 134.596 117.075 136.967 1.00 54.63  ? 277 LEU D CG  1 
ATOM   10338 C CD1 . LEU D 1 312 ? 134.100 116.443 138.253 1.00 47.99  ? 277 LEU D CD1 1 
ATOM   10339 C CD2 . LEU D 1 312 ? 134.472 116.081 135.827 1.00 48.50  ? 277 LEU D CD2 1 
ATOM   10340 N N   . PRO D 1 313 ? 133.961 118.976 133.403 1.00 57.50  ? 278 PRO D N   1 
ATOM   10341 C CA  . PRO D 1 313 ? 133.065 119.027 132.244 1.00 61.77  ? 278 PRO D CA  1 
ATOM   10342 C C   . PRO D 1 313 ? 131.709 118.432 132.587 1.00 66.85  ? 278 PRO D C   1 
ATOM   10343 O O   . PRO D 1 313 ? 131.592 117.544 133.434 1.00 68.86  ? 278 PRO D O   1 
ATOM   10344 C CB  . PRO D 1 313 ? 133.799 118.196 131.186 1.00 57.24  ? 278 PRO D CB  1 
ATOM   10345 C CG  . PRO D 1 313 ? 134.771 117.368 131.957 1.00 53.43  ? 278 PRO D CG  1 
ATOM   10346 C CD  . PRO D 1 313 ? 135.176 118.197 133.126 1.00 48.04  ? 278 PRO D CD  1 
ATOM   10347 N N   . LYS D 1 314 ? 130.674 118.928 131.912 1.00 67.02  ? 279 LYS D N   1 
ATOM   10348 C CA  . LYS D 1 314 ? 129.312 118.519 132.230 1.00 70.60  ? 279 LYS D CA  1 
ATOM   10349 C C   . LYS D 1 314 ? 129.051 117.090 131.770 1.00 67.41  ? 279 LYS D C   1 
ATOM   10350 O O   . LYS D 1 314 ? 128.314 116.864 130.805 1.00 69.66  ? 279 LYS D O   1 
ATOM   10351 C CB  . LYS D 1 314 ? 128.304 119.476 131.592 1.00 75.81  ? 279 LYS D CB  1 
ATOM   10352 C CG  . LYS D 1 314 ? 128.398 120.904 132.104 1.00 81.11  ? 279 LYS D CG  1 
ATOM   10353 C CD  . LYS D 1 314 ? 127.374 121.800 131.427 1.00 85.76  ? 279 LYS D CD  1 
ATOM   10354 C CE  . LYS D 1 314 ? 127.332 123.177 132.067 1.00 73.38  ? 279 LYS D CE  1 
ATOM   10355 N NZ  . LYS D 1 314 ? 126.307 124.048 131.431 1.00 60.73  ? 279 LYS D NZ  1 
ATOM   10356 N N   . VAL D 1 315 ? 129.654 116.120 132.456 1.00 59.20  ? 280 VAL D N   1 
ATOM   10357 C CA  . VAL D 1 315 ? 129.431 114.707 132.182 1.00 55.54  ? 280 VAL D CA  1 
ATOM   10358 C C   . VAL D 1 315 ? 128.469 114.153 133.222 1.00 58.40  ? 280 VAL D C   1 
ATOM   10359 O O   . VAL D 1 315 ? 128.435 114.602 134.374 1.00 63.15  ? 280 VAL D O   1 
ATOM   10360 C CB  . VAL D 1 315 ? 130.762 113.923 132.172 1.00 49.65  ? 280 VAL D CB  1 
ATOM   10361 C CG1 . VAL D 1 315 ? 131.789 114.637 131.315 1.00 52.78  ? 280 VAL D CG1 1 
ATOM   10362 C CG2 . VAL D 1 315 ? 131.294 113.740 133.583 1.00 50.73  ? 280 VAL D CG2 1 
ATOM   10363 N N   . ALA D 1 316 ? 127.650 113.189 132.806 1.00 57.22  ? 281 ALA D N   1 
ATOM   10364 C CA  . ALA D 1 316 ? 126.571 112.682 133.643 1.00 54.70  ? 281 ALA D CA  1 
ATOM   10365 C C   . ALA D 1 316 ? 126.980 111.483 134.488 1.00 51.73  ? 281 ALA D C   1 
ATOM   10366 O O   . ALA D 1 316 ? 126.131 110.924 135.190 1.00 50.94  ? 281 ALA D O   1 
ATOM   10367 C CB  . ALA D 1 316 ? 125.356 112.312 132.792 1.00 52.16  ? 281 ALA D CB  1 
ATOM   10368 N N   . TYR D 1 317 ? 128.240 111.072 134.440 1.00 49.21  ? 282 TYR D N   1 
ATOM   10369 C CA  . TYR D 1 317 ? 128.728 109.969 135.252 1.00 49.73  ? 282 TYR D CA  1 
ATOM   10370 C C   . TYR D 1 317 ? 129.650 110.496 136.344 1.00 51.71  ? 282 TYR D C   1 
ATOM   10371 O O   . TYR D 1 317 ? 130.011 111.675 136.375 1.00 52.59  ? 282 TYR D O   1 
ATOM   10372 C CB  . TYR D 1 317 ? 129.431 108.913 134.387 1.00 48.89  ? 282 TYR D CB  1 
ATOM   10373 C CG  . TYR D 1 317 ? 130.495 109.441 133.452 1.00 52.57  ? 282 TYR D CG  1 
ATOM   10374 C CD1 . TYR D 1 317 ? 130.168 109.874 132.176 1.00 56.68  ? 282 TYR D CD1 1 
ATOM   10375 C CD2 . TYR D 1 317 ? 131.830 109.475 133.833 1.00 50.34  ? 282 TYR D CD2 1 
ATOM   10376 C CE1 . TYR D 1 317 ? 131.134 110.345 131.311 1.00 64.96  ? 282 TYR D CE1 1 
ATOM   10377 C CE2 . TYR D 1 317 ? 132.805 109.946 132.973 1.00 50.80  ? 282 TYR D CE2 1 
ATOM   10378 C CZ  . TYR D 1 317 ? 132.450 110.378 131.714 1.00 59.00  ? 282 TYR D CZ  1 
ATOM   10379 O OH  . TYR D 1 317 ? 133.412 110.849 130.851 1.00 51.58  ? 282 TYR D OH  1 
ATOM   10380 N N   . ALA D 1 318 ? 130.025 109.603 137.252 1.00 48.47  ? 283 ALA D N   1 
ATOM   10381 C CA  . ALA D 1 318 ? 130.781 109.970 138.439 1.00 38.40  ? 283 ALA D CA  1 
ATOM   10382 C C   . ALA D 1 318 ? 132.269 109.753 138.208 1.00 39.77  ? 283 ALA D C   1 
ATOM   10383 O O   . ALA D 1 318 ? 132.682 108.730 137.654 1.00 40.97  ? 283 ALA D O   1 
ATOM   10384 C CB  . ALA D 1 318 ? 130.318 109.162 139.651 1.00 35.82  ? 283 ALA D CB  1 
ATOM   10385 N N   . THR D 1 319 ? 133.066 110.723 138.639 1.00 39.84  ? 284 THR D N   1 
ATOM   10386 C CA  . THR D 1 319 ? 134.509 110.723 138.461 1.00 36.08  ? 284 THR D CA  1 
ATOM   10387 C C   . THR D 1 319 ? 135.181 110.529 139.815 1.00 29.56  ? 284 THR D C   1 
ATOM   10388 O O   . THR D 1 319 ? 134.523 110.323 140.837 1.00 32.86  ? 284 THR D O   1 
ATOM   10389 C CB  . THR D 1 319 ? 134.963 112.032 137.816 1.00 34.74  ? 284 THR D CB  1 
ATOM   10390 O OG1 . THR D 1 319 ? 134.804 113.101 138.755 1.00 31.58  ? 284 THR D OG1 1 
ATOM   10391 C CG2 . THR D 1 319 ? 134.107 112.340 136.601 1.00 36.94  ? 284 THR D CG2 1 
ATOM   10392 N N   . ALA D 1 320 ? 136.513 110.604 139.822 1.00 28.25  ? 285 ALA D N   1 
ATOM   10393 C CA  . ALA D 1 320 ? 137.233 110.353 141.064 1.00 27.72  ? 285 ALA D CA  1 
ATOM   10394 C C   . ALA D 1 320 ? 137.083 111.513 142.035 1.00 27.94  ? 285 ALA D C   1 
ATOM   10395 O O   . ALA D 1 320 ? 137.189 111.320 143.251 1.00 28.21  ? 285 ALA D O   1 
ATOM   10396 C CB  . ALA D 1 320 ? 138.709 110.086 140.782 1.00 29.88  ? 285 ALA D CB  1 
ATOM   10397 N N   . MET D 1 321 ? 136.848 112.722 141.524 1.00 28.08  ? 286 MET D N   1 
ATOM   10398 C CA  . MET D 1 321 ? 136.610 113.854 142.410 1.00 27.10  ? 286 MET D CA  1 
ATOM   10399 C C   . MET D 1 321 ? 135.196 113.836 142.972 1.00 27.77  ? 286 MET D C   1 
ATOM   10400 O O   . MET D 1 321 ? 134.981 114.275 144.106 1.00 27.91  ? 286 MET D O   1 
ATOM   10401 C CB  . MET D 1 321 ? 136.888 115.167 141.679 1.00 28.37  ? 286 MET D CB  1 
ATOM   10402 C CG  . MET D 1 321 ? 137.012 116.365 142.605 1.00 29.98  ? 286 MET D CG  1 
ATOM   10403 S SD  . MET D 1 321 ? 137.602 117.847 141.765 1.00 48.33  ? 286 MET D SD  1 
ATOM   10404 C CE  . MET D 1 321 ? 136.344 118.051 140.514 1.00 42.09  ? 286 MET D CE  1 
ATOM   10405 N N   . ASP D 1 322 ? 134.224 113.339 142.200 1.00 31.45  ? 287 ASP D N   1 
ATOM   10406 C CA  . ASP D 1 322 ? 132.866 113.217 142.721 1.00 25.43  ? 287 ASP D CA  1 
ATOM   10407 C C   . ASP D 1 322 ? 132.820 112.246 143.891 1.00 22.93  ? 287 ASP D C   1 
ATOM   10408 O O   . ASP D 1 322 ? 132.142 112.501 144.892 1.00 25.81  ? 287 ASP D O   1 
ATOM   10409 C CB  . ASP D 1 322 ? 131.915 112.767 141.613 1.00 29.70  ? 287 ASP D CB  1 
ATOM   10410 C CG  . ASP D 1 322 ? 131.717 113.826 140.550 1.00 44.78  ? 287 ASP D CG  1 
ATOM   10411 O OD1 . ASP D 1 322 ? 131.885 115.022 140.864 1.00 52.84  ? 287 ASP D OD1 1 
ATOM   10412 O OD2 . ASP D 1 322 ? 131.395 113.465 139.399 1.00 50.80  ? 287 ASP D OD2 1 
ATOM   10413 N N   . TRP D 1 323 ? 133.522 111.116 143.776 1.00 22.29  ? 288 TRP D N   1 
ATOM   10414 C CA  . TRP D 1 323 ? 133.506 110.130 144.850 1.00 20.81  ? 288 TRP D CA  1 
ATOM   10415 C C   . TRP D 1 323 ? 134.187 110.674 146.098 1.00 22.03  ? 288 TRP D C   1 
ATOM   10416 O O   . TRP D 1 323 ? 133.734 110.421 147.220 1.00 23.94  ? 288 TRP D O   1 
ATOM   10417 C CB  . TRP D 1 323 ? 134.162 108.828 144.395 1.00 24.87  ? 288 TRP D CB  1 
ATOM   10418 C CG  . TRP D 1 323 ? 133.306 108.039 143.456 1.00 30.77  ? 288 TRP D CG  1 
ATOM   10419 C CD1 . TRP D 1 323 ? 133.553 107.776 142.142 1.00 31.96  ? 288 TRP D CD1 1 
ATOM   10420 C CD2 . TRP D 1 323 ? 132.045 107.431 143.757 1.00 33.20  ? 288 TRP D CD2 1 
ATOM   10421 N NE1 . TRP D 1 323 ? 132.531 107.029 141.608 1.00 31.34  ? 288 TRP D NE1 1 
ATOM   10422 C CE2 . TRP D 1 323 ? 131.591 106.805 142.580 1.00 32.51  ? 288 TRP D CE2 1 
ATOM   10423 C CE3 . TRP D 1 323 ? 131.258 107.348 144.910 1.00 30.10  ? 288 TRP D CE3 1 
ATOM   10424 C CZ2 . TRP D 1 323 ? 130.388 106.109 142.522 1.00 31.75  ? 288 TRP D CZ2 1 
ATOM   10425 C CZ3 . TRP D 1 323 ? 130.065 106.657 144.851 1.00 30.93  ? 288 TRP D CZ3 1 
ATOM   10426 C CH2 . TRP D 1 323 ? 129.641 106.046 143.665 1.00 32.88  ? 288 TRP D CH2 1 
ATOM   10427 N N   . PHE D 1 324 ? 135.281 111.419 145.920 1.00 22.14  ? 289 PHE D N   1 
ATOM   10428 C CA  . PHE D 1 324 ? 135.957 112.026 147.060 1.00 22.07  ? 289 PHE D CA  1 
ATOM   10429 C C   . PHE D 1 324 ? 135.051 113.033 147.754 1.00 20.99  ? 289 PHE D C   1 
ATOM   10430 O O   . PHE D 1 324 ? 135.016 113.103 148.988 1.00 20.17  ? 289 PHE D O   1 
ATOM   10431 C CB  . PHE D 1 324 ? 137.253 112.692 146.596 1.00 21.17  ? 289 PHE D CB  1 
ATOM   10432 C CG  . PHE D 1 324 ? 138.073 113.279 147.707 1.00 21.87  ? 289 PHE D CG  1 
ATOM   10433 C CD1 . PHE D 1 324 ? 138.985 112.499 148.396 1.00 23.81  ? 289 PHE D CD1 1 
ATOM   10434 C CD2 . PHE D 1 324 ? 137.948 114.612 148.051 1.00 21.65  ? 289 PHE D CD2 1 
ATOM   10435 C CE1 . PHE D 1 324 ? 139.747 113.034 149.412 1.00 24.20  ? 289 PHE D CE1 1 
ATOM   10436 C CE2 . PHE D 1 324 ? 138.706 115.152 149.068 1.00 23.67  ? 289 PHE D CE2 1 
ATOM   10437 C CZ  . PHE D 1 324 ? 139.607 114.362 149.750 1.00 24.19  ? 289 PHE D CZ  1 
ATOM   10438 N N   . ILE D 1 325 ? 134.318 113.831 146.976 1.00 21.31  ? 290 ILE D N   1 
ATOM   10439 C CA  . ILE D 1 325 ? 133.415 114.811 147.567 1.00 16.99  ? 290 ILE D CA  1 
ATOM   10440 C C   . ILE D 1 325 ? 132.236 114.110 148.230 1.00 18.53  ? 290 ILE D C   1 
ATOM   10441 O O   . ILE D 1 325 ? 131.771 114.523 149.299 1.00 20.95  ? 290 ILE D O   1 
ATOM   10442 C CB  . ILE D 1 325 ? 132.957 115.816 146.495 1.00 16.89  ? 290 ILE D CB  1 
ATOM   10443 C CG1 . ILE D 1 325 ? 134.050 116.853 146.246 1.00 18.38  ? 290 ILE D CG1 1 
ATOM   10444 C CG2 . ILE D 1 325 ? 131.669 116.503 146.908 1.00 19.17  ? 290 ILE D CG2 1 
ATOM   10445 C CD1 . ILE D 1 325 ? 133.811 117.697 145.028 1.00 17.46  ? 290 ILE D CD1 1 
ATOM   10446 N N   . ALA D 1 326 ? 131.742 113.032 147.614 1.00 20.79  ? 291 ALA D N   1 
ATOM   10447 C CA  . ALA D 1 326 ? 130.632 112.289 148.200 1.00 16.84  ? 291 ALA D CA  1 
ATOM   10448 C C   . ALA D 1 326 ? 131.021 111.688 149.543 1.00 17.03  ? 291 ALA D C   1 
ATOM   10449 O O   . ALA D 1 326 ? 130.212 111.661 150.477 1.00 16.96  ? 291 ALA D O   1 
ATOM   10450 C CB  . ALA D 1 326 ? 130.164 111.198 147.239 1.00 16.62  ? 291 ALA D CB  1 
ATOM   10451 N N   . VAL D 1 327 ? 132.254 111.189 149.656 1.00 17.95  ? 292 VAL D N   1 
ATOM   10452 C CA  . VAL D 1 327 ? 132.703 110.630 150.926 1.00 17.82  ? 292 VAL D CA  1 
ATOM   10453 C C   . VAL D 1 327 ? 132.862 111.737 151.959 1.00 18.45  ? 292 VAL D C   1 
ATOM   10454 O O   . VAL D 1 327 ? 132.470 111.584 153.122 1.00 19.85  ? 292 VAL D O   1 
ATOM   10455 C CB  . VAL D 1 327 ? 134.007 109.838 150.729 1.00 17.33  ? 292 VAL D CB  1 
ATOM   10456 C CG1 . VAL D 1 327 ? 134.665 109.550 152.064 1.00 16.86  ? 292 VAL D CG1 1 
ATOM   10457 C CG2 . VAL D 1 327 ? 133.730 108.546 149.981 1.00 18.49  ? 292 VAL D CG2 1 
ATOM   10458 N N   . CYS D 1 328 ? 133.439 112.869 151.551 1.00 18.21  ? 293 CYS D N   1 
ATOM   10459 C CA  . CYS D 1 328 ? 133.553 114.011 152.451 1.00 18.06  ? 293 CYS D CA  1 
ATOM   10460 C C   . CYS D 1 328 ? 132.178 114.517 152.864 1.00 18.36  ? 293 CYS D C   1 
ATOM   10461 O O   . CYS D 1 328 ? 131.975 114.918 154.016 1.00 18.83  ? 293 CYS D O   1 
ATOM   10462 C CB  . CYS D 1 328 ? 134.358 115.127 151.785 1.00 19.76  ? 293 CYS D CB  1 
ATOM   10463 S SG  . CYS D 1 328 ? 136.123 114.781 151.611 1.00 27.80  ? 293 CYS D SG  1 
ATOM   10464 N N   . TYR D 1 329 ? 131.224 114.517 151.929 1.00 19.85  ? 294 TYR D N   1 
ATOM   10465 C CA  . TYR D 1 329 ? 129.845 114.848 152.274 1.00 16.49  ? 294 TYR D CA  1 
ATOM   10466 C C   . TYR D 1 329 ? 129.295 113.889 153.321 1.00 16.85  ? 294 TYR D C   1 
ATOM   10467 O O   . TYR D 1 329 ? 128.607 114.310 154.257 1.00 19.14  ? 294 TYR D O   1 
ATOM   10468 C CB  . TYR D 1 329 ? 128.970 114.826 151.023 1.00 16.59  ? 294 TYR D CB  1 
ATOM   10469 C CG  . TYR D 1 329 ? 127.979 115.960 150.957 1.00 18.22  ? 294 TYR D CG  1 
ATOM   10470 C CD1 . TYR D 1 329 ? 126.941 116.056 151.874 1.00 20.15  ? 294 TYR D CD1 1 
ATOM   10471 C CD2 . TYR D 1 329 ? 128.073 116.930 149.970 1.00 16.39  ? 294 TYR D CD2 1 
ATOM   10472 C CE1 . TYR D 1 329 ? 126.032 117.094 151.817 1.00 22.60  ? 294 TYR D CE1 1 
ATOM   10473 C CE2 . TYR D 1 329 ? 127.168 117.968 149.902 1.00 19.46  ? 294 TYR D CE2 1 
ATOM   10474 C CZ  . TYR D 1 329 ? 126.151 118.046 150.828 1.00 23.48  ? 294 TYR D CZ  1 
ATOM   10475 O OH  . TYR D 1 329 ? 125.247 119.081 150.763 1.00 26.38  ? 294 TYR D OH  1 
ATOM   10476 N N   . ALA D 1 330 ? 129.577 112.593 153.173 1.00 16.62  ? 295 ALA D N   1 
ATOM   10477 C CA  . ALA D 1 330 ? 129.066 111.617 154.129 1.00 14.29  ? 295 ALA D CA  1 
ATOM   10478 C C   . ALA D 1 330 ? 129.743 111.766 155.485 1.00 14.50  ? 295 ALA D C   1 
ATOM   10479 O O   . ALA D 1 330 ? 129.107 111.570 156.526 1.00 17.67  ? 295 ALA D O   1 
ATOM   10480 C CB  . ALA D 1 330 ? 129.253 110.201 153.588 1.00 13.10  ? 295 ALA D CB  1 
ATOM   10481 N N   . PHE D 1 331 ? 131.034 112.107 155.495 1.00 14.61  ? 296 PHE D N   1 
ATOM   10482 C CA  . PHE D 1 331 ? 131.734 112.319 156.758 1.00 16.15  ? 296 PHE D CA  1 
ATOM   10483 C C   . PHE D 1 331 ? 131.216 113.558 157.475 1.00 18.13  ? 296 PHE D C   1 
ATOM   10484 O O   . PHE D 1 331 ? 131.053 113.552 158.701 1.00 19.85  ? 296 PHE D O   1 
ATOM   10485 C CB  . PHE D 1 331 ? 133.238 112.435 156.516 1.00 17.61  ? 296 PHE D CB  1 
ATOM   10486 C CG  . PHE D 1 331 ? 133.970 111.131 156.618 1.00 19.94  ? 296 PHE D CG  1 
ATOM   10487 C CD1 . PHE D 1 331 ? 134.472 110.699 157.832 1.00 23.15  ? 296 PHE D CD1 1 
ATOM   10488 C CD2 . PHE D 1 331 ? 134.162 110.340 155.499 1.00 20.18  ? 296 PHE D CD2 1 
ATOM   10489 C CE1 . PHE D 1 331 ? 135.148 109.502 157.930 1.00 26.95  ? 296 PHE D CE1 1 
ATOM   10490 C CE2 . PHE D 1 331 ? 134.838 109.141 155.590 1.00 22.04  ? 296 PHE D CE2 1 
ATOM   10491 C CZ  . PHE D 1 331 ? 135.331 108.722 156.807 1.00 25.74  ? 296 PHE D CZ  1 
ATOM   10492 N N   . VAL D 1 332 ? 130.969 114.635 156.729 1.00 17.30  ? 297 VAL D N   1 
ATOM   10493 C CA  . VAL D 1 332 ? 130.440 115.854 157.331 1.00 15.45  ? 297 VAL D CA  1 
ATOM   10494 C C   . VAL D 1 332 ? 129.005 115.636 157.796 1.00 16.99  ? 297 VAL D C   1 
ATOM   10495 O O   . VAL D 1 332 ? 128.607 116.101 158.871 1.00 18.72  ? 297 VAL D O   1 
ATOM   10496 C CB  . VAL D 1 332 ? 130.559 117.022 156.337 1.00 12.86  ? 297 VAL D CB  1 
ATOM   10497 C CG1 . VAL D 1 332 ? 129.702 118.181 156.771 1.00 14.80  ? 297 VAL D CG1 1 
ATOM   10498 C CG2 . VAL D 1 332 ? 132.006 117.455 156.217 1.00 15.02  ? 297 VAL D CG2 1 
ATOM   10499 N N   . PHE D 1 333 ? 128.208 114.922 156.996 1.00 15.75  ? 298 PHE D N   1 
ATOM   10500 C CA  . PHE D 1 333 ? 126.844 114.594 157.398 1.00 14.78  ? 298 PHE D CA  1 
ATOM   10501 C C   . PHE D 1 333 ? 126.829 113.749 158.664 1.00 17.30  ? 298 PHE D C   1 
ATOM   10502 O O   . PHE D 1 333 ? 126.024 113.989 159.571 1.00 20.75  ? 298 PHE D O   1 
ATOM   10503 C CB  . PHE D 1 333 ? 126.123 113.873 156.256 1.00 15.30  ? 298 PHE D CB  1 
ATOM   10504 C CG  . PHE D 1 333 ? 124.899 113.109 156.687 1.00 16.98  ? 298 PHE D CG  1 
ATOM   10505 C CD1 . PHE D 1 333 ? 123.653 113.709 156.676 1.00 16.62  ? 298 PHE D CD1 1 
ATOM   10506 C CD2 . PHE D 1 333 ? 124.989 111.778 157.065 1.00 17.86  ? 298 PHE D CD2 1 
ATOM   10507 C CE1 . PHE D 1 333 ? 122.528 113.007 157.065 1.00 17.28  ? 298 PHE D CE1 1 
ATOM   10508 C CE2 . PHE D 1 333 ? 123.867 111.074 157.454 1.00 18.67  ? 298 PHE D CE2 1 
ATOM   10509 C CZ  . PHE D 1 333 ? 122.636 111.689 157.451 1.00 15.78  ? 298 PHE D CZ  1 
ATOM   10510 N N   . SER D 1 334 ? 127.714 112.753 158.744 1.00 15.69  ? 299 SER D N   1 
ATOM   10511 C CA  . SER D 1 334 ? 127.733 111.871 159.904 1.00 16.47  ? 299 SER D CA  1 
ATOM   10512 C C   . SER D 1 334 ? 128.156 112.605 161.168 1.00 19.41  ? 299 SER D C   1 
ATOM   10513 O O   . SER D 1 334 ? 127.688 112.266 162.260 1.00 26.18  ? 299 SER D O   1 
ATOM   10514 C CB  . SER D 1 334 ? 128.659 110.683 159.650 1.00 17.27  ? 299 SER D CB  1 
ATOM   10515 O OG  . SER D 1 334 ? 128.269 109.980 158.486 1.00 21.09  ? 299 SER D OG  1 
ATOM   10516 N N   . ALA D 1 335 ? 129.045 113.593 161.049 1.00 16.49  ? 300 ALA D N   1 
ATOM   10517 C CA  . ALA D 1 335 ? 129.473 114.328 162.234 1.00 19.74  ? 300 ALA D CA  1 
ATOM   10518 C C   . ALA D 1 335 ? 128.306 115.066 162.875 1.00 22.73  ? 300 ALA D C   1 
ATOM   10519 O O   . ALA D 1 335 ? 128.204 115.132 164.105 1.00 26.97  ? 300 ALA D O   1 
ATOM   10520 C CB  . ALA D 1 335 ? 130.591 115.304 161.871 1.00 21.17  ? 300 ALA D CB  1 
ATOM   10521 N N   . LEU D 1 336 ? 127.418 115.639 162.059 1.00 20.87  ? 301 LEU D N   1 
ATOM   10522 C CA  . LEU D 1 336 ? 126.241 116.294 162.617 1.00 19.48  ? 301 LEU D CA  1 
ATOM   10523 C C   . LEU D 1 336 ? 125.230 115.276 163.129 1.00 21.12  ? 301 LEU D C   1 
ATOM   10524 O O   . LEU D 1 336 ? 124.516 115.547 164.100 1.00 25.00  ? 301 LEU D O   1 
ATOM   10525 C CB  . LEU D 1 336 ? 125.602 117.208 161.576 1.00 16.99  ? 301 LEU D CB  1 
ATOM   10526 C CG  . LEU D 1 336 ? 124.371 117.990 162.029 1.00 15.50  ? 301 LEU D CG  1 
ATOM   10527 C CD1 . LEU D 1 336 ? 124.630 118.686 163.354 1.00 16.00  ? 301 LEU D CD1 1 
ATOM   10528 C CD2 . LEU D 1 336 ? 123.993 118.996 160.975 1.00 16.49  ? 301 LEU D CD2 1 
ATOM   10529 N N   . ILE D 1 337 ? 125.162 114.100 162.501 1.00 19.86  ? 302 ILE D N   1 
ATOM   10530 C CA  . ILE D 1 337 ? 124.327 113.032 163.036 1.00 19.26  ? 302 ILE D CA  1 
ATOM   10531 C C   . ILE D 1 337 ? 124.936 112.486 164.318 1.00 23.13  ? 302 ILE D C   1 
ATOM   10532 O O   . ILE D 1 337 ? 124.213 112.058 165.227 1.00 29.17  ? 302 ILE D O   1 
ATOM   10533 C CB  . ILE D 1 337 ? 124.137 111.931 161.975 1.00 17.94  ? 302 ILE D CB  1 
ATOM   10534 C CG1 . ILE D 1 337 ? 123.239 112.433 160.846 1.00 18.02  ? 302 ILE D CG1 1 
ATOM   10535 C CG2 . ILE D 1 337 ? 123.552 110.667 162.588 1.00 17.91  ? 302 ILE D CG2 1 
ATOM   10536 C CD1 . ILE D 1 337 ? 121.781 112.529 161.225 1.00 22.48  ? 302 ILE D CD1 1 
ATOM   10537 N N   . GLU D 1 338 ? 126.266 112.508 164.422 1.00 22.08  ? 303 GLU D N   1 
ATOM   10538 C CA  . GLU D 1 338 ? 126.923 112.068 165.647 1.00 23.61  ? 303 GLU D CA  1 
ATOM   10539 C C   . GLU D 1 338 ? 126.507 112.942 166.824 1.00 28.53  ? 303 GLU D C   1 
ATOM   10540 O O   . GLU D 1 338 ? 126.201 112.440 167.911 1.00 33.36  ? 303 GLU D O   1 
ATOM   10541 C CB  . GLU D 1 338 ? 128.440 112.074 165.443 1.00 24.75  ? 303 GLU D CB  1 
ATOM   10542 C CG  . GLU D 1 338 ? 129.274 111.638 166.638 1.00 30.12  ? 303 GLU D CG  1 
ATOM   10543 C CD  . GLU D 1 338 ? 129.722 112.793 167.511 1.00 36.26  ? 303 GLU D CD  1 
ATOM   10544 O OE1 . GLU D 1 338 ? 129.232 113.924 167.322 1.00 39.30  ? 303 GLU D OE1 1 
ATOM   10545 O OE2 . GLU D 1 338 ? 130.583 112.566 168.384 1.00 38.93  ? 303 GLU D OE2 1 
ATOM   10546 N N   . PHE D 1 339 ? 126.496 114.263 166.623 1.00 27.14  ? 304 PHE D N   1 
ATOM   10547 C CA  . PHE D 1 339 ? 126.127 115.172 167.703 1.00 30.50  ? 304 PHE D CA  1 
ATOM   10548 C C   . PHE D 1 339 ? 124.652 115.042 168.065 1.00 31.49  ? 304 PHE D C   1 
ATOM   10549 O O   . PHE D 1 339 ? 124.287 115.199 169.236 1.00 36.35  ? 304 PHE D O   1 
ATOM   10550 C CB  . PHE D 1 339 ? 126.455 116.613 167.315 1.00 31.35  ? 304 PHE D CB  1 
ATOM   10551 C CG  . PHE D 1 339 ? 125.823 117.638 168.209 1.00 35.80  ? 304 PHE D CG  1 
ATOM   10552 C CD1 . PHE D 1 339 ? 126.272 117.812 169.507 1.00 36.30  ? 304 PHE D CD1 1 
ATOM   10553 C CD2 . PHE D 1 339 ? 124.779 118.424 167.755 1.00 32.65  ? 304 PHE D CD2 1 
ATOM   10554 C CE1 . PHE D 1 339 ? 125.693 118.751 170.334 1.00 35.07  ? 304 PHE D CE1 1 
ATOM   10555 C CE2 . PHE D 1 339 ? 124.196 119.364 168.578 1.00 34.84  ? 304 PHE D CE2 1 
ATOM   10556 C CZ  . PHE D 1 339 ? 124.655 119.528 169.870 1.00 37.63  ? 304 PHE D CZ  1 
ATOM   10557 N N   . ALA D 1 340 ? 123.796 114.765 167.077 1.00 28.71  ? 305 ALA D N   1 
ATOM   10558 C CA  . ALA D 1 340 ? 122.377 114.559 167.349 1.00 26.88  ? 305 ALA D CA  1 
ATOM   10559 C C   . ALA D 1 340 ? 122.162 113.400 168.311 1.00 28.93  ? 305 ALA D C   1 
ATOM   10560 O O   . ALA D 1 340 ? 121.255 113.437 169.150 1.00 31.97  ? 305 ALA D O   1 
ATOM   10561 C CB  . ALA D 1 340 ? 121.622 114.315 166.043 1.00 24.30  ? 305 ALA D CB  1 
ATOM   10562 N N   . THR D 1 341 ? 122.982 112.354 168.194 1.00 27.61  ? 306 THR D N   1 
ATOM   10563 C CA  . THR D 1 341 ? 122.882 111.227 169.113 1.00 28.54  ? 306 THR D CA  1 
ATOM   10564 C C   . THR D 1 341 ? 123.450 111.583 170.480 1.00 35.34  ? 306 THR D C   1 
ATOM   10565 O O   . THR D 1 341 ? 122.901 111.180 171.510 1.00 39.67  ? 306 THR D O   1 
ATOM   10566 C CB  . THR D 1 341 ? 123.600 110.011 168.534 1.00 29.76  ? 306 THR D CB  1 
ATOM   10567 O OG1 . THR D 1 341 ? 123.174 109.804 167.182 1.00 28.31  ? 306 THR D OG1 1 
ATOM   10568 C CG2 . THR D 1 341 ? 123.278 108.773 169.351 1.00 37.32  ? 306 THR D CG2 1 
ATOM   10569 N N   . VAL D 1 342 ? 124.547 112.343 170.506 1.00 34.08  ? 307 VAL D N   1 
ATOM   10570 C CA  . VAL D 1 342 ? 125.120 112.796 171.772 1.00 34.12  ? 307 VAL D CA  1 
ATOM   10571 C C   . VAL D 1 342 ? 124.112 113.645 172.535 1.00 41.09  ? 307 VAL D C   1 
ATOM   10572 O O   . VAL D 1 342 ? 123.913 113.471 173.743 1.00 44.70  ? 307 VAL D O   1 
ATOM   10573 C CB  . VAL D 1 342 ? 126.429 113.566 171.525 1.00 28.81  ? 307 VAL D CB  1 
ATOM   10574 C CG1 . VAL D 1 342 ? 126.875 114.275 172.794 1.00 38.41  ? 307 VAL D CG1 1 
ATOM   10575 C CG2 . VAL D 1 342 ? 127.509 112.630 171.025 1.00 31.92  ? 307 VAL D CG2 1 
ATOM   10576 N N   . ASN D 1 343 ? 123.460 114.580 171.840 1.00 42.37  ? 308 ASN D N   1 
ATOM   10577 C CA  . ASN D 1 343 ? 122.527 115.476 172.512 1.00 41.60  ? 308 ASN D CA  1 
ATOM   10578 C C   . ASN D 1 343 ? 121.332 114.721 173.080 1.00 42.25  ? 308 ASN D C   1 
ATOM   10579 O O   . ASN D 1 343 ? 120.751 115.153 174.082 1.00 45.68  ? 308 ASN D O   1 
ATOM   10580 C CB  . ASN D 1 343 ? 122.057 116.561 171.544 1.00 40.17  ? 308 ASN D CB  1 
ATOM   10581 C CG  . ASN D 1 343 ? 121.067 117.516 172.176 1.00 48.14  ? 308 ASN D CG  1 
ATOM   10582 O OD1 . ASN D 1 343 ? 119.858 117.389 171.991 1.00 52.99  ? 308 ASN D OD1 1 
ATOM   10583 N ND2 . ASN D 1 343 ? 121.578 118.482 172.926 1.00 43.01  ? 308 ASN D ND2 1 
ATOM   10584 N N   . TYR D 1 344 ? 120.951 113.598 172.463 1.00 39.68  ? 309 TYR D N   1 
ATOM   10585 C CA  . TYR D 1 344 ? 119.815 112.833 172.965 1.00 42.88  ? 309 TYR D CA  1 
ATOM   10586 C C   . TYR D 1 344 ? 120.078 112.286 174.361 1.00 47.76  ? 309 TYR D C   1 
ATOM   10587 O O   . TYR D 1 344 ? 119.139 112.104 175.144 1.00 48.02  ? 309 TYR D O   1 
ATOM   10588 C CB  . TYR D 1 344 ? 119.484 111.685 172.012 1.00 45.07  ? 309 TYR D CB  1 
ATOM   10589 C CG  . TYR D 1 344 ? 118.168 111.009 172.319 1.00 51.02  ? 309 TYR D CG  1 
ATOM   10590 C CD1 . TYR D 1 344 ? 116.961 111.604 171.983 1.00 53.28  ? 309 TYR D CD1 1 
ATOM   10591 C CD2 . TYR D 1 344 ? 118.134 109.779 172.964 1.00 48.61  ? 309 TYR D CD2 1 
ATOM   10592 C CE1 . TYR D 1 344 ? 115.758 110.989 172.270 1.00 52.63  ? 309 TYR D CE1 1 
ATOM   10593 C CE2 . TYR D 1 344 ? 116.937 109.157 173.255 1.00 47.34  ? 309 TYR D CE2 1 
ATOM   10594 C CZ  . TYR D 1 344 ? 115.753 109.766 172.906 1.00 54.06  ? 309 TYR D CZ  1 
ATOM   10595 O OH  . TYR D 1 344 ? 114.558 109.149 173.194 1.00 61.44  ? 309 TYR D OH  1 
ATOM   10596 N N   . PHE D 1 345 ? 121.340 112.021 174.691 1.00 45.44  ? 310 PHE D N   1 
ATOM   10597 C CA  . PHE D 1 345 ? 121.719 111.484 175.989 1.00 44.48  ? 310 PHE D CA  1 
ATOM   10598 C C   . PHE D 1 345 ? 122.308 112.541 176.912 1.00 45.86  ? 310 PHE D C   1 
ATOM   10599 O O   . PHE D 1 345 ? 122.854 112.196 177.964 1.00 48.35  ? 310 PHE D O   1 
ATOM   10600 C CB  . PHE D 1 345 ? 122.702 110.324 175.817 1.00 45.00  ? 310 PHE D CB  1 
ATOM   10601 C CG  . PHE D 1 345 ? 122.151 109.181 175.015 1.00 45.52  ? 310 PHE D CG  1 
ATOM   10602 C CD1 . PHE D 1 345 ? 121.383 108.203 175.621 1.00 49.04  ? 310 PHE D CD1 1 
ATOM   10603 C CD2 . PHE D 1 345 ? 122.398 109.083 173.658 1.00 44.08  ? 310 PHE D CD2 1 
ATOM   10604 C CE1 . PHE D 1 345 ? 120.873 107.150 174.889 1.00 49.12  ? 310 PHE D CE1 1 
ATOM   10605 C CE2 . PHE D 1 345 ? 121.891 108.032 172.920 1.00 44.82  ? 310 PHE D CE2 1 
ATOM   10606 C CZ  . PHE D 1 345 ? 121.128 107.065 173.537 1.00 49.16  ? 310 PHE D CZ  1 
ATOM   10607 N N   . THR D 1 346 ? 122.206 113.816 176.550 1.00 49.78  ? 311 THR D N   1 
ATOM   10608 C CA  . THR D 1 346 ? 122.613 114.885 177.449 1.00 55.21  ? 311 THR D CA  1 
ATOM   10609 C C   . THR D 1 346 ? 121.502 115.161 178.453 1.00 55.92  ? 311 THR D C   1 
ATOM   10610 O O   . THR D 1 346 ? 120.327 115.255 178.086 1.00 51.83  ? 311 THR D O   1 
ATOM   10611 C CB  . THR D 1 346 ? 122.937 116.154 176.662 1.00 54.43  ? 311 THR D CB  1 
ATOM   10612 O OG1 . THR D 1 346 ? 123.771 115.827 175.544 1.00 49.06  ? 311 THR D OG1 1 
ATOM   10613 C CG2 . THR D 1 346 ? 123.659 117.158 177.546 1.00 56.95  ? 311 THR D CG2 1 
ATOM   10614 N N   . LYS D 1 347 ? 121.880 115.299 179.721 1.00 64.76  ? 312 LYS D N   1 
ATOM   10615 C CA  . LYS D 1 347 ? 120.926 115.461 180.811 1.00 71.25  ? 312 LYS D CA  1 
ATOM   10616 C C   . LYS D 1 347 ? 120.854 116.909 181.282 1.00 75.65  ? 312 LYS D C   1 
ATOM   10617 O O   . LYS D 1 347 ? 119.775 117.507 181.314 1.00 78.79  ? 312 LYS D O   1 
ATOM   10618 C CB  . LYS D 1 347 ? 121.300 114.524 181.967 1.00 72.65  ? 312 LYS D CB  1 
ATOM   10619 C CG  . LYS D 1 347 ? 121.261 113.053 181.584 1.00 69.16  ? 312 LYS D CG  1 
ATOM   10620 C CD  . LYS D 1 347 ? 121.668 112.160 182.741 1.00 64.71  ? 312 LYS D CD  1 
ATOM   10621 C CE  . LYS D 1 347 ? 121.735 110.705 182.310 1.00 62.47  ? 312 LYS D CE  1 
ATOM   10622 N NZ  . LYS D 1 347 ? 122.083 109.809 183.445 1.00 71.23  ? 312 LYS D NZ  1 
ATOM   10623 N N   . ARG D 1 348 ? 121.994 117.482 181.657 1.00 75.07  ? 313 ARG D N   1 
ATOM   10624 C CA  . ARG D 1 348 ? 122.041 118.815 182.239 1.00 75.92  ? 313 ARG D CA  1 
ATOM   10625 C C   . ARG D 1 348 ? 122.322 119.835 181.145 1.00 82.21  ? 313 ARG D C   1 
ATOM   10626 O O   . ARG D 1 348 ? 123.195 119.621 180.298 1.00 81.17  ? 313 ARG D O   1 
ATOM   10627 C CB  . ARG D 1 348 ? 123.119 118.879 183.319 1.00 75.79  ? 313 ARG D CB  1 
ATOM   10628 C CG  . ARG D 1 348 ? 122.988 117.785 184.359 1.00 76.38  ? 313 ARG D CG  1 
ATOM   10629 C CD  . ARG D 1 348 ? 124.267 117.624 185.156 1.00 81.28  ? 313 ARG D CD  1 
ATOM   10630 N NE  . ARG D 1 348 ? 124.207 116.474 186.049 1.00 78.28  ? 313 ARG D NE  1 
ATOM   10631 C CZ  . ARG D 1 348 ? 124.426 115.222 185.672 1.00 77.49  ? 313 ARG D CZ  1 
ATOM   10632 N NH1 . ARG D 1 348 ? 124.714 114.918 184.417 1.00 76.19  ? 313 ARG D NH1 1 
ATOM   10633 N NH2 . ARG D 1 348 ? 124.353 114.249 186.576 1.00 80.43  ? 313 ARG D NH2 1 
ATOM   10634 N N   . GLY D 1 349 ? 121.577 120.937 181.158 1.00 85.29  ? 314 GLY D N   1 
ATOM   10635 C CA  . GLY D 1 349 ? 121.748 121.962 180.151 1.00 87.75  ? 314 GLY D CA  1 
ATOM   10636 C C   . GLY D 1 349 ? 122.881 122.933 180.384 1.00 89.89  ? 314 GLY D C   1 
ATOM   10637 O O   . GLY D 1 349 ? 123.085 123.835 179.566 1.00 90.68  ? 314 GLY D O   1 
ATOM   10638 N N   . TYR D 1 350 ? 123.633 122.775 181.469 1.00 88.64  ? 315 TYR D N   1 
ATOM   10639 C CA  . TYR D 1 350 ? 124.745 123.655 181.797 1.00 84.96  ? 315 TYR D CA  1 
ATOM   10640 C C   . TYR D 1 350 ? 126.059 122.893 181.701 1.00 85.55  ? 315 TYR D C   1 
ATOM   10641 O O   . TYR D 1 350 ? 126.131 121.713 182.060 1.00 84.80  ? 315 TYR D O   1 
ATOM   10642 C CB  . TYR D 1 350 ? 124.584 124.249 183.199 1.00 84.53  ? 315 TYR D CB  1 
ATOM   10643 C CG  . TYR D 1 350 ? 124.289 123.231 184.278 1.00 86.87  ? 315 TYR D CG  1 
ATOM   10644 C CD1 . TYR D 1 350 ? 125.318 122.574 184.941 1.00 85.03  ? 315 TYR D CD1 1 
ATOM   10645 C CD2 . TYR D 1 350 ? 122.982 122.928 184.636 1.00 86.56  ? 315 TYR D CD2 1 
ATOM   10646 C CE1 . TYR D 1 350 ? 125.054 121.645 185.926 1.00 85.81  ? 315 TYR D CE1 1 
ATOM   10647 C CE2 . TYR D 1 350 ? 122.709 121.999 185.622 1.00 87.31  ? 315 TYR D CE2 1 
ATOM   10648 C CZ  . TYR D 1 350 ? 123.749 121.361 186.264 1.00 89.08  ? 315 TYR D CZ  1 
ATOM   10649 O OH  . TYR D 1 350 ? 123.483 120.437 187.247 1.00 92.14  ? 315 TYR D OH  1 
ATOM   10650 N N   . ALA D 1 351 ? 127.095 123.570 181.217 1.00 84.88  ? 316 ALA D N   1 
ATOM   10651 C CA  . ALA D 1 351 ? 128.404 122.956 181.073 1.00 79.19  ? 316 ALA D CA  1 
ATOM   10652 C C   . ALA D 1 351 ? 129.180 123.047 182.382 1.00 79.04  ? 316 ALA D C   1 
ATOM   10653 O O   . ALA D 1 351 ? 128.737 123.659 183.357 1.00 82.71  ? 316 ALA D O   1 
ATOM   10654 C CB  . ALA D 1 351 ? 129.188 123.620 179.941 1.00 66.29  ? 316 ALA D CB  1 
ATOM   10655 N N   . TRP D 1 352 ? 130.350 122.412 182.401 1.00 77.50  ? 317 TRP D N   1 
ATOM   10656 C CA  . TRP D 1 352 ? 131.207 122.474 183.575 1.00 82.82  ? 317 TRP D CA  1 
ATOM   10657 C C   . TRP D 1 352 ? 131.572 123.922 183.875 1.00 86.07  ? 317 TRP D C   1 
ATOM   10658 O O   . TRP D 1 352 ? 131.961 124.676 182.979 1.00 86.08  ? 317 TRP D O   1 
ATOM   10659 C CB  . TRP D 1 352 ? 132.466 121.636 183.355 1.00 78.80  ? 317 TRP D CB  1 
ATOM   10660 C CG  . TRP D 1 352 ? 133.395 121.628 184.527 1.00 84.89  ? 317 TRP D CG  1 
ATOM   10661 C CD1 . TRP D 1 352 ? 133.102 121.232 185.798 1.00 87.59  ? 317 TRP D CD1 1 
ATOM   10662 C CD2 . TRP D 1 352 ? 134.772 122.022 184.539 1.00 88.50  ? 317 TRP D CD2 1 
ATOM   10663 N NE1 . TRP D 1 352 ? 134.206 121.361 186.603 1.00 88.08  ? 317 TRP D NE1 1 
ATOM   10664 C CE2 . TRP D 1 352 ? 135.246 121.843 185.854 1.00 88.82  ? 317 TRP D CE2 1 
ATOM   10665 C CE3 . TRP D 1 352 ? 135.649 122.511 183.567 1.00 91.50  ? 317 TRP D CE3 1 
ATOM   10666 C CZ2 . TRP D 1 352 ? 136.557 122.137 186.221 1.00 90.04  ? 317 TRP D CZ2 1 
ATOM   10667 C CZ3 . TRP D 1 352 ? 136.951 122.801 183.935 1.00 92.75  ? 317 TRP D CZ3 1 
ATOM   10668 C CH2 . TRP D 1 352 ? 137.392 122.612 185.250 1.00 90.16  ? 317 TRP D CH2 1 
ATOM   10669 N N   . ASP D 1 353 ? 131.438 124.312 185.142 1.00 87.64  ? 318 ASP D N   1 
ATOM   10670 C CA  . ASP D 1 353 ? 131.600 125.713 185.504 1.00 84.24  ? 318 ASP D CA  1 
ATOM   10671 C C   . ASP D 1 353 ? 133.057 126.151 185.551 1.00 84.56  ? 318 ASP D C   1 
ATOM   10672 O O   . ASP D 1 353 ? 133.328 127.356 185.537 1.00 82.86  ? 318 ASP D O   1 
ATOM   10673 C CB  . ASP D 1 353 ? 130.927 125.982 186.852 1.00 81.85  ? 318 ASP D CB  1 
ATOM   10674 C CG  . ASP D 1 353 ? 131.413 125.049 187.944 1.00 85.62  ? 318 ASP D CG  1 
ATOM   10675 O OD1 . ASP D 1 353 ? 132.335 124.246 187.686 1.00 86.18  ? 318 ASP D OD1 1 
ATOM   10676 O OD2 . ASP D 1 353 ? 130.869 125.118 189.066 1.00 88.18  ? 318 ASP D OD2 1 
ATOM   10677 N N   . GLY D 1 354 ? 133.996 125.209 185.604 1.00 82.69  ? 319 GLY D N   1 
ATOM   10678 C CA  . GLY D 1 354 ? 135.403 125.533 185.605 1.00 82.71  ? 319 GLY D CA  1 
ATOM   10679 C C   . GLY D 1 354 ? 136.023 125.688 186.976 1.00 84.63  ? 319 GLY D C   1 
ATOM   10680 O O   . GLY D 1 354 ? 137.255 125.759 187.076 1.00 86.14  ? 319 GLY D O   1 
ATOM   10681 N N   . LYS D 1 355 ? 135.215 125.743 188.034 1.00 86.98  ? 320 LYS D N   1 
ATOM   10682 C CA  . LYS D 1 355 ? 135.720 125.869 189.396 1.00 89.56  ? 320 LYS D CA  1 
ATOM   10683 C C   . LYS D 1 355 ? 135.738 124.530 190.125 1.00 89.52  ? 320 LYS D C   1 
ATOM   10684 O O   . LYS D 1 355 ? 136.788 124.092 190.603 1.00 86.59  ? 320 LYS D O   1 
ATOM   10685 C CB  . LYS D 1 355 ? 134.870 126.891 190.165 1.00 85.64  ? 320 LYS D CB  1 
ATOM   10686 C CG  . LYS D 1 355 ? 134.912 128.290 189.572 1.00 84.58  ? 320 LYS D CG  1 
ATOM   10687 C CD  . LYS D 1 355 ? 134.138 129.283 190.421 1.00 91.32  ? 320 LYS D CD  1 
ATOM   10688 C CE  . LYS D 1 355 ? 134.281 130.695 189.877 1.00 98.05  ? 320 LYS D CE  1 
ATOM   10689 N NZ  . LYS D 1 355 ? 133.525 131.687 190.692 1.00 102.42 ? 320 LYS D NZ  1 
ATOM   10690 N N   . SER D 1 356 ? 134.589 123.868 190.214 1.00 88.02  ? 321 SER D N   1 
ATOM   10691 C CA  . SER D 1 356 ? 134.489 122.590 190.908 1.00 85.09  ? 321 SER D CA  1 
ATOM   10692 C C   . SER D 1 356 ? 135.108 121.464 190.085 1.00 81.72  ? 321 SER D C   1 
ATOM   10693 O O   . SER D 1 356 ? 134.999 120.290 190.440 1.00 75.89  ? 321 SER D O   1 
ATOM   10694 C CB  . SER D 1 356 ? 133.028 122.270 191.225 1.00 82.44  ? 321 SER D CB  1 
ATOM   10695 O OG  . SER D 1 356 ? 132.232 122.335 190.056 1.00 77.03  ? 321 SER D OG  1 
ATOM   10696 N N   . LYS D 1 419 ? 126.076 119.913 193.286 1.00 93.17  ? 384 LYS D N   1 
ATOM   10697 C CA  . LYS D 1 419 ? 125.988 120.217 191.863 1.00 93.53  ? 384 LYS D CA  1 
ATOM   10698 C C   . LYS D 1 419 ? 126.768 119.202 191.038 1.00 94.78  ? 384 LYS D C   1 
ATOM   10699 O O   . LYS D 1 419 ? 127.969 119.016 191.239 1.00 93.19  ? 384 LYS D O   1 
ATOM   10700 C CB  . LYS D 1 419 ? 126.505 121.630 191.584 1.00 87.17  ? 384 LYS D CB  1 
ATOM   10701 C CG  . LYS D 1 419 ? 126.167 122.157 190.197 1.00 81.68  ? 384 LYS D CG  1 
ATOM   10702 C CD  . LYS D 1 419 ? 126.642 123.591 190.022 1.00 82.28  ? 384 LYS D CD  1 
ATOM   10703 C CE  . LYS D 1 419 ? 126.275 124.133 188.652 1.00 82.88  ? 384 LYS D CE  1 
ATOM   10704 N NZ  . LYS D 1 419 ? 126.829 125.498 188.428 1.00 81.49  ? 384 LYS D NZ  1 
ATOM   10705 N N   . THR D 1 420 ? 126.080 118.545 190.111 1.00 93.61  ? 385 THR D N   1 
ATOM   10706 C CA  . THR D 1 420 ? 126.683 117.550 189.239 1.00 89.53  ? 385 THR D CA  1 
ATOM   10707 C C   . THR D 1 420 ? 126.773 118.087 187.817 1.00 84.27  ? 385 THR D C   1 
ATOM   10708 O O   . THR D 1 420 ? 126.091 119.045 187.445 1.00 84.70  ? 385 THR D O   1 
ATOM   10709 C CB  . THR D 1 420 ? 125.882 116.245 189.252 1.00 92.03  ? 385 THR D CB  1 
ATOM   10710 O OG1 . THR D 1 420 ? 124.489 116.537 189.087 1.00 95.20  ? 385 THR D OG1 1 
ATOM   10711 C CG2 . THR D 1 420 ? 126.086 115.509 190.567 1.00 90.93  ? 385 THR D CG2 1 
ATOM   10712 N N   . PHE D 1 421 ? 127.638 117.460 187.024 1.00 81.31  ? 386 PHE D N   1 
ATOM   10713 C CA  . PHE D 1 421 ? 127.888 117.884 185.656 1.00 81.43  ? 386 PHE D CA  1 
ATOM   10714 C C   . PHE D 1 421 ? 127.865 116.677 184.732 1.00 80.33  ? 386 PHE D C   1 
ATOM   10715 O O   . PHE D 1 421 ? 128.074 115.538 185.156 1.00 86.98  ? 386 PHE D O   1 
ATOM   10716 C CB  . PHE D 1 421 ? 129.235 118.606 185.522 1.00 82.47  ? 386 PHE D CB  1 
ATOM   10717 C CG  . PHE D 1 421 ? 129.368 119.810 186.404 1.00 82.81  ? 386 PHE D CG  1 
ATOM   10718 C CD1 . PHE D 1 421 ? 128.960 121.056 185.963 1.00 81.52  ? 386 PHE D CD1 1 
ATOM   10719 C CD2 . PHE D 1 421 ? 129.912 119.697 187.670 1.00 84.12  ? 386 PHE D CD2 1 
ATOM   10720 C CE1 . PHE D 1 421 ? 129.085 122.165 186.773 1.00 84.35  ? 386 PHE D CE1 1 
ATOM   10721 C CE2 . PHE D 1 421 ? 130.040 120.801 188.483 1.00 83.13  ? 386 PHE D CE2 1 
ATOM   10722 C CZ  . PHE D 1 421 ? 129.626 122.037 188.036 1.00 84.50  ? 386 PHE D CZ  1 
ATOM   10723 N N   . ASN D 1 422 ? 127.602 116.941 183.456 1.00 76.53  ? 387 ASN D N   1 
ATOM   10724 C CA  . ASN D 1 422 ? 127.604 115.881 182.462 1.00 72.55  ? 387 ASN D CA  1 
ATOM   10725 C C   . ASN D 1 422 ? 129.007 115.309 182.308 1.00 71.24  ? 387 ASN D C   1 
ATOM   10726 O O   . ASN D 1 422 ? 130.010 115.998 182.510 1.00 71.61  ? 387 ASN D O   1 
ATOM   10727 C CB  . ASN D 1 422 ? 127.092 116.397 181.118 1.00 67.37  ? 387 ASN D CB  1 
ATOM   10728 C CG  . ASN D 1 422 ? 125.678 116.930 181.201 1.00 73.19  ? 387 ASN D CG  1 
ATOM   10729 O OD1 . ASN D 1 422 ? 124.873 116.463 182.007 1.00 79.74  ? 387 ASN D OD1 1 
ATOM   10730 N ND2 . ASN D 1 422 ? 125.365 117.910 180.363 1.00 69.60  ? 387 ASN D ND2 1 
ATOM   10731 N N   . SER D 1 423 ? 129.072 114.033 181.952 1.00 68.90  ? 388 SER D N   1 
ATOM   10732 C CA  . SER D 1 423 ? 130.342 113.393 181.654 1.00 70.39  ? 388 SER D CA  1 
ATOM   10733 C C   . SER D 1 423 ? 130.632 113.476 180.162 1.00 65.12  ? 388 SER D C   1 
ATOM   10734 O O   . SER D 1 423 ? 129.720 113.578 179.337 1.00 60.20  ? 388 SER D O   1 
ATOM   10735 C CB  . SER D 1 423 ? 130.333 111.933 182.107 1.00 66.13  ? 388 SER D CB  1 
ATOM   10736 O OG  . SER D 1 423 ? 129.338 111.193 181.421 1.00 66.92  ? 388 SER D OG  1 
ATOM   10737 N N   . VAL D 1 424 ? 131.924 113.450 179.823 1.00 56.21  ? 389 VAL D N   1 
ATOM   10738 C CA  . VAL D 1 424 ? 132.324 113.487 178.423 1.00 46.08  ? 389 VAL D CA  1 
ATOM   10739 C C   . VAL D 1 424 ? 131.714 112.298 177.701 1.00 48.38  ? 389 VAL D C   1 
ATOM   10740 O O   . VAL D 1 424 ? 131.853 111.148 178.135 1.00 55.75  ? 389 VAL D O   1 
ATOM   10741 C CB  . VAL D 1 424 ? 133.855 113.497 178.303 1.00 43.98  ? 389 VAL D CB  1 
ATOM   10742 C CG1 . VAL D 1 424 ? 134.269 113.457 176.842 1.00 46.75  ? 389 VAL D CG1 1 
ATOM   10743 C CG2 . VAL D 1 424 ? 134.430 114.723 178.990 1.00 40.54  ? 389 VAL D CG2 1 
ATOM   10744 N N   . SER D 1 425 ? 131.018 112.576 176.602 1.00 47.48  ? 390 SER D N   1 
ATOM   10745 C CA  . SER D 1 425 ? 130.277 111.540 175.895 1.00 53.63  ? 390 SER D CA  1 
ATOM   10746 C C   . SER D 1 425 ? 131.197 110.416 175.443 1.00 53.92  ? 390 SER D C   1 
ATOM   10747 O O   . SER D 1 425 ? 132.267 110.661 174.880 1.00 53.46  ? 390 SER D O   1 
ATOM   10748 C CB  . SER D 1 425 ? 129.559 112.146 174.689 1.00 50.40  ? 390 SER D CB  1 
ATOM   10749 O OG  . SER D 1 425 ? 128.799 111.169 174.002 1.00 51.54  ? 390 SER D OG  1 
ATOM   10750 N N   . LYS D 1 426 ? 130.772 109.174 175.692 1.00 56.58  ? 391 LYS D N   1 
ATOM   10751 C CA  . LYS D 1 426 ? 131.513 108.032 175.170 1.00 51.23  ? 391 LYS D CA  1 
ATOM   10752 C C   . LYS D 1 426 ? 131.427 107.983 173.651 1.00 46.38  ? 391 LYS D C   1 
ATOM   10753 O O   . LYS D 1 426 ? 132.329 107.453 172.993 1.00 40.48  ? 391 LYS D O   1 
ATOM   10754 C CB  . LYS D 1 426 ? 130.988 106.738 175.791 1.00 51.65  ? 391 LYS D CB  1 
ATOM   10755 C CG  . LYS D 1 426 ? 131.271 106.626 177.284 1.00 61.95  ? 391 LYS D CG  1 
ATOM   10756 C CD  . LYS D 1 426 ? 130.894 105.263 177.861 1.00 69.88  ? 391 LYS D CD  1 
ATOM   10757 C CE  . LYS D 1 426 ? 129.402 105.150 178.166 1.00 65.24  ? 391 LYS D CE  1 
ATOM   10758 N NZ  . LYS D 1 426 ? 128.546 105.080 176.951 1.00 62.07  ? 391 LYS D NZ  1 
ATOM   10759 N N   . ILE D 1 427 ? 130.344 108.520 173.085 1.00 49.64  ? 392 ILE D N   1 
ATOM   10760 C CA  . ILE D 1 427 ? 130.242 108.664 171.638 1.00 43.38  ? 392 ILE D CA  1 
ATOM   10761 C C   . ILE D 1 427 ? 131.327 109.603 171.130 1.00 41.16  ? 392 ILE D C   1 
ATOM   10762 O O   . ILE D 1 427 ? 131.957 109.350 170.097 1.00 44.06  ? 392 ILE D O   1 
ATOM   10763 C CB  . ILE D 1 427 ? 128.838 109.158 171.246 1.00 43.27  ? 392 ILE D CB  1 
ATOM   10764 C CG1 . ILE D 1 427 ? 127.772 108.178 171.729 1.00 40.94  ? 392 ILE D CG1 1 
ATOM   10765 C CG2 . ILE D 1 427 ? 128.735 109.327 169.740 1.00 39.97  ? 392 ILE D CG2 1 
ATOM   10766 C CD1 . ILE D 1 427 ? 126.362 108.687 171.566 1.00 35.10  ? 392 ILE D CD1 1 
ATOM   10767 N N   . ASP D 1 428 ? 131.562 110.701 171.854 1.00 37.97  ? 393 ASP D N   1 
ATOM   10768 C CA  . ASP D 1 428 ? 132.600 111.654 171.467 1.00 41.45  ? 393 ASP D CA  1 
ATOM   10769 C C   . ASP D 1 428 ? 133.986 111.028 171.544 1.00 41.28  ? 393 ASP D C   1 
ATOM   10770 O O   . ASP D 1 428 ? 134.792 111.169 170.617 1.00 41.99  ? 393 ASP D O   1 
ATOM   10771 C CB  . ASP D 1 428 ? 132.531 112.894 172.360 1.00 44.54  ? 393 ASP D CB  1 
ATOM   10772 C CG  . ASP D 1 428 ? 131.563 113.938 171.841 1.00 46.29  ? 393 ASP D CG  1 
ATOM   10773 O OD1 . ASP D 1 428 ? 131.349 113.997 170.614 1.00 46.73  ? 393 ASP D OD1 1 
ATOM   10774 O OD2 . ASP D 1 428 ? 131.020 114.706 172.663 1.00 49.08  ? 393 ASP D OD2 1 
ATOM   10775 N N   . ARG D 1 429 ? 134.288 110.345 172.651 1.00 41.69  ? 394 ARG D N   1 
ATOM   10776 C CA  . ARG D 1 429 ? 135.606 109.735 172.809 1.00 38.89  ? 394 ARG D CA  1 
ATOM   10777 C C   . ARG D 1 429 ? 135.914 108.771 171.671 1.00 39.22  ? 394 ARG D C   1 
ATOM   10778 O O   . ARG D 1 429 ? 137.030 108.761 171.141 1.00 41.18  ? 394 ARG D O   1 
ATOM   10779 C CB  . ARG D 1 429 ? 135.698 109.025 174.158 1.00 46.99  ? 394 ARG D CB  1 
ATOM   10780 C CG  . ARG D 1 429 ? 135.561 109.952 175.353 1.00 56.17  ? 394 ARG D CG  1 
ATOM   10781 C CD  . ARG D 1 429 ? 135.599 109.186 176.667 1.00 71.25  ? 394 ARG D CD  1 
ATOM   10782 N NE  . ARG D 1 429 ? 136.891 108.549 176.892 1.00 89.57  ? 394 ARG D NE  1 
ATOM   10783 C CZ  . ARG D 1 429 ? 137.203 107.850 177.975 1.00 92.34  ? 394 ARG D CZ  1 
ATOM   10784 N NH1 . ARG D 1 429 ? 136.336 107.673 178.958 1.00 95.59  ? 394 ARG D NH1 1 
ATOM   10785 N NH2 . ARG D 1 429 ? 138.416 107.313 178.073 1.00 88.92  ? 394 ARG D NH2 1 
ATOM   10786 N N   . LEU D 1 430 ? 134.938 107.950 171.281 1.00 40.67  ? 395 LEU D N   1 
ATOM   10787 C CA  . LEU D 1 430 ? 135.143 107.058 170.145 1.00 35.70  ? 395 LEU D CA  1 
ATOM   10788 C C   . LEU D 1 430 ? 135.191 107.831 168.834 1.00 34.34  ? 395 LEU D C   1 
ATOM   10789 O O   . LEU D 1 430 ? 136.030 107.548 167.972 1.00 36.83  ? 395 LEU D O   1 
ATOM   10790 C CB  . LEU D 1 430 ? 134.046 105.997 170.100 1.00 34.85  ? 395 LEU D CB  1 
ATOM   10791 C CG  . LEU D 1 430 ? 134.070 105.072 168.881 1.00 33.99  ? 395 LEU D CG  1 
ATOM   10792 C CD1 . LEU D 1 430 ? 135.423 104.393 168.744 1.00 38.45  ? 395 LEU D CD1 1 
ATOM   10793 C CD2 . LEU D 1 430 ? 132.965 104.038 168.980 1.00 39.16  ? 395 LEU D CD2 1 
ATOM   10794 N N   . SER D 1 431 ? 134.300 108.810 168.662 1.00 35.94  ? 396 SER D N   1 
ATOM   10795 C CA  . SER D 1 431 ? 134.249 109.557 167.413 1.00 34.26  ? 396 SER D CA  1 
ATOM   10796 C C   . SER D 1 431 ? 135.483 110.417 167.187 1.00 36.43  ? 396 SER D C   1 
ATOM   10797 O O   . SER D 1 431 ? 135.803 110.721 166.033 1.00 37.37  ? 396 SER D O   1 
ATOM   10798 C CB  . SER D 1 431 ? 133.000 110.439 167.374 1.00 31.99  ? 396 SER D CB  1 
ATOM   10799 O OG  . SER D 1 431 ? 131.834 109.685 167.655 1.00 31.18  ? 396 SER D OG  1 
ATOM   10800 N N   . ARG D 1 432 ? 136.182 110.818 168.253 1.00 36.95  ? 397 ARG D N   1 
ATOM   10801 C CA  . ARG D 1 432 ? 137.431 111.547 168.075 1.00 36.72  ? 397 ARG D CA  1 
ATOM   10802 C C   . ARG D 1 432 ? 138.513 110.682 167.445 1.00 41.77  ? 397 ARG D C   1 
ATOM   10803 O O   . ARG D 1 432 ? 139.490 111.221 166.917 1.00 50.67  ? 397 ARG D O   1 
ATOM   10804 C CB  . ARG D 1 432 ? 137.923 112.097 169.415 1.00 39.20  ? 397 ARG D CB  1 
ATOM   10805 C CG  . ARG D 1 432 ? 137.099 113.248 169.960 1.00 36.16  ? 397 ARG D CG  1 
ATOM   10806 C CD  . ARG D 1 432 ? 137.430 113.517 171.418 1.00 36.27  ? 397 ARG D CD  1 
ATOM   10807 N NE  . ARG D 1 432 ? 136.625 114.600 171.968 1.00 36.00  ? 397 ARG D NE  1 
ATOM   10808 C CZ  . ARG D 1 432 ? 136.638 114.971 173.241 1.00 41.55  ? 397 ARG D CZ  1 
ATOM   10809 N NH1 . ARG D 1 432 ? 137.409 114.367 174.129 1.00 52.32  ? 397 ARG D NH1 1 
ATOM   10810 N NH2 . ARG D 1 432 ? 135.853 115.970 173.633 1.00 41.59  ? 397 ARG D NH2 1 
ATOM   10811 N N   . ILE D 1 433 ? 138.371 109.362 167.502 1.00 37.93  ? 398 ILE D N   1 
ATOM   10812 C CA  . ILE D 1 433 ? 139.339 108.432 166.936 1.00 35.24  ? 398 ILE D CA  1 
ATOM   10813 C C   . ILE D 1 433 ? 138.807 107.779 165.666 1.00 33.69  ? 398 ILE D C   1 
ATOM   10814 O O   . ILE D 1 433 ? 139.505 107.711 164.654 1.00 31.80  ? 398 ILE D O   1 
ATOM   10815 C CB  . ILE D 1 433 ? 139.754 107.366 167.975 1.00 39.62  ? 398 ILE D CB  1 
ATOM   10816 C CG1 . ILE D 1 433 ? 140.402 108.029 169.190 1.00 43.51  ? 398 ILE D CG1 1 
ATOM   10817 C CG2 . ILE D 1 433 ? 140.687 106.343 167.351 1.00 39.86  ? 398 ILE D CG2 1 
ATOM   10818 C CD1 . ILE D 1 433 ? 140.558 107.105 170.376 1.00 49.58  ? 398 ILE D CD1 1 
ATOM   10819 N N   . ALA D 1 434 ? 137.567 107.287 165.707 1.00 40.13  ? 399 ALA D N   1 
ATOM   10820 C CA  . ALA D 1 434 ? 137.012 106.560 164.568 1.00 37.93  ? 399 ALA D CA  1 
ATOM   10821 C C   . ALA D 1 434 ? 136.891 107.454 163.341 1.00 36.61  ? 399 ALA D C   1 
ATOM   10822 O O   . ALA D 1 434 ? 137.260 107.055 162.230 1.00 34.47  ? 399 ALA D O   1 
ATOM   10823 C CB  . ALA D 1 434 ? 135.652 105.969 164.937 1.00 28.70  ? 399 ALA D CB  1 
ATOM   10824 N N   . PHE D 1 435 ? 136.370 108.672 163.521 1.00 35.03  ? 400 PHE D N   1 
ATOM   10825 C CA  . PHE D 1 435 ? 136.153 109.543 162.366 1.00 31.65  ? 400 PHE D CA  1 
ATOM   10826 C C   . PHE D 1 435 ? 137.468 109.941 161.704 1.00 31.28  ? 400 PHE D C   1 
ATOM   10827 O O   . PHE D 1 435 ? 137.579 109.801 160.474 1.00 31.57  ? 400 PHE D O   1 
ATOM   10828 C CB  . PHE D 1 435 ? 135.312 110.756 162.779 1.00 28.43  ? 400 PHE D CB  1 
ATOM   10829 C CG  . PHE D 1 435 ? 133.831 110.525 162.698 1.00 28.92  ? 400 PHE D CG  1 
ATOM   10830 C CD1 . PHE D 1 435 ? 133.165 109.880 163.725 1.00 29.57  ? 400 PHE D CD1 1 
ATOM   10831 C CD2 . PHE D 1 435 ? 133.105 110.948 161.600 1.00 28.61  ? 400 PHE D CD2 1 
ATOM   10832 C CE1 . PHE D 1 435 ? 131.805 109.664 163.661 1.00 28.19  ? 400 PHE D CE1 1 
ATOM   10833 C CE2 . PHE D 1 435 ? 131.744 110.734 161.530 1.00 26.09  ? 400 PHE D CE2 1 
ATOM   10834 C CZ  . PHE D 1 435 ? 131.094 110.092 162.562 1.00 25.43  ? 400 PHE D CZ  1 
ATOM   10835 N N   . PRO D 1 436 ? 138.480 110.454 162.422 1.00 30.02  ? 401 PRO D N   1 
ATOM   10836 C CA  . PRO D 1 436 ? 139.771 110.713 161.761 1.00 29.94  ? 401 PRO D CA  1 
ATOM   10837 C C   . PRO D 1 436 ? 140.397 109.477 161.137 1.00 32.85  ? 401 PRO D C   1 
ATOM   10838 O O   . PRO D 1 436 ? 140.994 109.570 160.057 1.00 33.49  ? 401 PRO D O   1 
ATOM   10839 C CB  . PRO D 1 436 ? 140.638 111.273 162.894 1.00 28.66  ? 401 PRO D CB  1 
ATOM   10840 C CG  . PRO D 1 436 ? 139.684 111.870 163.835 1.00 28.59  ? 401 PRO D CG  1 
ATOM   10841 C CD  . PRO D 1 436 ? 138.454 111.018 163.785 1.00 28.84  ? 401 PRO D CD  1 
ATOM   10842 N N   . LEU D 1 437 ? 140.285 108.320 161.792 1.00 32.87  ? 402 LEU D N   1 
ATOM   10843 C CA  . LEU D 1 437 ? 140.907 107.107 161.268 1.00 33.30  ? 402 LEU D CA  1 
ATOM   10844 C C   . LEU D 1 437 ? 140.226 106.643 159.987 1.00 32.78  ? 402 LEU D C   1 
ATOM   10845 O O   . LEU D 1 437 ? 140.898 106.293 159.011 1.00 33.23  ? 402 LEU D O   1 
ATOM   10846 C CB  . LEU D 1 437 ? 140.876 106.004 162.325 1.00 33.92  ? 402 LEU D CB  1 
ATOM   10847 C CG  . LEU D 1 437 ? 141.475 104.655 161.929 1.00 36.75  ? 402 LEU D CG  1 
ATOM   10848 C CD1 . LEU D 1 437 ? 142.963 104.795 161.661 1.00 37.50  ? 402 LEU D CD1 1 
ATOM   10849 C CD2 . LEU D 1 437 ? 141.217 103.617 163.009 1.00 36.69  ? 402 LEU D CD2 1 
ATOM   10850 N N   . LEU D 1 438 ? 138.891 106.627 159.970 1.00 31.56  ? 403 LEU D N   1 
ATOM   10851 C CA  . LEU D 1 438 ? 138.190 106.172 158.774 1.00 29.97  ? 403 LEU D CA  1 
ATOM   10852 C C   . LEU D 1 438 ? 138.490 107.087 157.596 1.00 28.61  ? 403 LEU D C   1 
ATOM   10853 O O   . LEU D 1 438 ? 138.686 106.619 156.469 1.00 30.09  ? 403 LEU D O   1 
ATOM   10854 C CB  . LEU D 1 438 ? 136.686 106.100 159.031 1.00 30.90  ? 403 LEU D CB  1 
ATOM   10855 C CG  . LEU D 1 438 ? 136.211 105.016 159.998 1.00 36.36  ? 403 LEU D CG  1 
ATOM   10856 C CD1 . LEU D 1 438 ? 134.778 105.278 160.430 1.00 37.68  ? 403 LEU D CD1 1 
ATOM   10857 C CD2 . LEU D 1 438 ? 136.346 103.640 159.368 1.00 36.49  ? 403 LEU D CD2 1 
ATOM   10858 N N   . PHE D 1 439 ? 138.519 108.400 157.836 1.00 27.89  ? 404 PHE D N   1 
ATOM   10859 C CA  . PHE D 1 439 ? 138.917 109.326 156.784 1.00 26.33  ? 404 PHE D CA  1 
ATOM   10860 C C   . PHE D 1 439 ? 140.371 109.109 156.389 1.00 29.97  ? 404 PHE D C   1 
ATOM   10861 O O   . PHE D 1 439 ? 140.712 109.158 155.202 1.00 30.44  ? 404 PHE D O   1 
ATOM   10862 C CB  . PHE D 1 439 ? 138.687 110.767 157.235 1.00 23.23  ? 404 PHE D CB  1 
ATOM   10863 C CG  . PHE D 1 439 ? 138.788 111.770 156.124 1.00 20.69  ? 404 PHE D CG  1 
ATOM   10864 C CD1 . PHE D 1 439 ? 137.862 111.779 155.096 1.00 20.78  ? 404 PHE D CD1 1 
ATOM   10865 C CD2 . PHE D 1 439 ? 139.801 112.712 156.114 1.00 18.56  ? 404 PHE D CD2 1 
ATOM   10866 C CE1 . PHE D 1 439 ? 137.950 112.700 154.075 1.00 18.54  ? 404 PHE D CE1 1 
ATOM   10867 C CE2 . PHE D 1 439 ? 139.891 113.636 155.096 1.00 16.83  ? 404 PHE D CE2 1 
ATOM   10868 C CZ  . PHE D 1 439 ? 138.965 113.630 154.075 1.00 17.98  ? 404 PHE D CZ  1 
ATOM   10869 N N   . GLY D 1 440 ? 141.246 108.878 157.372 1.00 30.86  ? 405 GLY D N   1 
ATOM   10870 C CA  . GLY D 1 440 ? 142.632 108.576 157.051 1.00 30.98  ? 405 GLY D CA  1 
ATOM   10871 C C   . GLY D 1 440 ? 142.776 107.328 156.201 1.00 32.88  ? 405 GLY D C   1 
ATOM   10872 O O   . GLY D 1 440 ? 143.557 107.303 155.247 1.00 31.35  ? 405 GLY D O   1 
ATOM   10873 N N   . ILE D 1 441 ? 142.034 106.271 156.543 1.00 36.24  ? 406 ILE D N   1 
ATOM   10874 C CA  . ILE D 1 441 ? 142.077 105.041 155.755 1.00 36.42  ? 406 ILE D CA  1 
ATOM   10875 C C   . ILE D 1 441 ? 141.560 105.302 154.348 1.00 35.54  ? 406 ILE D C   1 
ATOM   10876 O O   . ILE D 1 441 ? 142.154 104.865 153.355 1.00 36.62  ? 406 ILE D O   1 
ATOM   10877 C CB  . ILE D 1 441 ? 141.281 103.923 156.451 1.00 35.73  ? 406 ILE D CB  1 
ATOM   10878 C CG1 . ILE D 1 441 ? 141.977 103.495 157.742 1.00 38.03  ? 406 ILE D CG1 1 
ATOM   10879 C CG2 . ILE D 1 441 ? 141.099 102.735 155.518 1.00 29.22  ? 406 ILE D CG2 1 
ATOM   10880 C CD1 . ILE D 1 441 ? 141.246 102.404 158.489 1.00 37.48  ? 406 ILE D CD1 1 
ATOM   10881 N N   . PHE D 1 442 ? 140.434 106.013 154.247 1.00 33.64  ? 407 PHE D N   1 
ATOM   10882 C CA  . PHE D 1 442 ? 139.849 106.311 152.944 1.00 31.19  ? 407 PHE D CA  1 
ATOM   10883 C C   . PHE D 1 442 ? 140.837 107.053 152.057 1.00 36.05  ? 407 PHE D C   1 
ATOM   10884 O O   . PHE D 1 442 ? 140.924 106.783 150.854 1.00 39.82  ? 407 PHE D O   1 
ATOM   10885 C CB  . PHE D 1 442 ? 138.565 107.122 153.110 1.00 25.36  ? 407 PHE D CB  1 
ATOM   10886 C CG  . PHE D 1 442 ? 138.164 107.873 151.876 1.00 26.10  ? 407 PHE D CG  1 
ATOM   10887 C CD1 . PHE D 1 442 ? 137.632 107.205 150.788 1.00 27.81  ? 407 PHE D CD1 1 
ATOM   10888 C CD2 . PHE D 1 442 ? 138.316 109.246 151.803 1.00 24.86  ? 407 PHE D CD2 1 
ATOM   10889 C CE1 . PHE D 1 442 ? 137.262 107.890 149.650 1.00 25.27  ? 407 PHE D CE1 1 
ATOM   10890 C CE2 . PHE D 1 442 ? 137.947 109.936 150.667 1.00 24.75  ? 407 PHE D CE2 1 
ATOM   10891 C CZ  . PHE D 1 442 ? 137.420 109.257 149.590 1.00 24.93  ? 407 PHE D CZ  1 
ATOM   10892 N N   . ASN D 1 443 ? 141.590 107.992 152.633 1.00 32.83  ? 408 ASN D N   1 
ATOM   10893 C CA  . ASN D 1 443 ? 142.544 108.757 151.839 1.00 33.85  ? 408 ASN D CA  1 
ATOM   10894 C C   . ASN D 1 443 ? 143.642 107.859 151.285 1.00 38.70  ? 408 ASN D C   1 
ATOM   10895 O O   . ASN D 1 443 ? 143.999 107.964 150.107 1.00 37.09  ? 408 ASN D O   1 
ATOM   10896 C CB  . ASN D 1 443 ? 143.147 109.880 152.680 1.00 33.01  ? 408 ASN D CB  1 
ATOM   10897 C CG  . ASN D 1 443 ? 142.259 111.101 152.742 1.00 33.64  ? 408 ASN D CG  1 
ATOM   10898 O OD1 . ASN D 1 443 ? 141.380 111.286 151.902 1.00 34.13  ? 408 ASN D OD1 1 
ATOM   10899 N ND2 . ASN D 1 443 ? 142.487 111.949 153.737 1.00 35.15  ? 408 ASN D ND2 1 
ATOM   10900 N N   . LEU D 1 444 ? 144.180 106.961 152.115 1.00 38.17  ? 409 LEU D N   1 
ATOM   10901 C CA  . LEU D 1 444 ? 145.217 106.053 151.640 1.00 36.89  ? 409 LEU D CA  1 
ATOM   10902 C C   . LEU D 1 444 ? 144.688 105.144 150.539 1.00 38.55  ? 409 LEU D C   1 
ATOM   10903 O O   . LEU D 1 444 ? 145.352 104.948 149.515 1.00 41.73  ? 409 LEU D O   1 
ATOM   10904 C CB  . LEU D 1 444 ? 145.765 105.223 152.800 1.00 32.49  ? 409 LEU D CB  1 
ATOM   10905 C CG  . LEU D 1 444 ? 146.453 105.994 153.925 1.00 39.33  ? 409 LEU D CG  1 
ATOM   10906 C CD1 . LEU D 1 444 ? 146.890 105.044 155.027 1.00 44.33  ? 409 LEU D CD1 1 
ATOM   10907 C CD2 . LEU D 1 444 ? 147.635 106.784 153.394 1.00 35.29  ? 409 LEU D CD2 1 
ATOM   10908 N N   . VAL D 1 445 ? 143.491 104.586 150.727 1.00 37.78  ? 410 VAL D N   1 
ATOM   10909 C CA  . VAL D 1 445 ? 142.894 103.742 149.695 1.00 39.50  ? 410 VAL D CA  1 
ATOM   10910 C C   . VAL D 1 445 ? 142.602 104.558 148.443 1.00 40.84  ? 410 VAL D C   1 
ATOM   10911 O O   . VAL D 1 445 ? 142.793 104.087 147.316 1.00 41.34  ? 410 VAL D O   1 
ATOM   10912 C CB  . VAL D 1 445 ? 141.627 103.055 150.235 1.00 34.19  ? 410 VAL D CB  1 
ATOM   10913 C CG1 . VAL D 1 445 ? 140.938 102.267 149.134 1.00 40.09  ? 410 VAL D CG1 1 
ATOM   10914 C CG2 . VAL D 1 445 ? 141.974 102.151 151.405 1.00 33.72  ? 410 VAL D CG2 1 
ATOM   10915 N N   . TYR D 1 446 ? 142.140 105.797 148.620 1.00 36.58  ? 411 TYR D N   1 
ATOM   10916 C CA  . TYR D 1 446 ? 141.790 106.629 147.474 1.00 36.15  ? 411 TYR D CA  1 
ATOM   10917 C C   . TYR D 1 446 ? 143.030 107.045 146.692 1.00 39.30  ? 411 TYR D C   1 
ATOM   10918 O O   . TYR D 1 446 ? 143.069 106.925 145.463 1.00 41.16  ? 411 TYR D O   1 
ATOM   10919 C CB  . TYR D 1 446 ? 141.011 107.859 147.938 1.00 31.68  ? 411 TYR D CB  1 
ATOM   10920 C CG  . TYR D 1 446 ? 140.661 108.825 146.830 1.00 31.01  ? 411 TYR D CG  1 
ATOM   10921 C CD1 . TYR D 1 446 ? 139.534 108.633 146.048 1.00 29.43  ? 411 TYR D CD1 1 
ATOM   10922 C CD2 . TYR D 1 446 ? 141.454 109.934 146.573 1.00 30.86  ? 411 TYR D CD2 1 
ATOM   10923 C CE1 . TYR D 1 446 ? 139.208 109.514 145.040 1.00 29.90  ? 411 TYR D CE1 1 
ATOM   10924 C CE2 . TYR D 1 446 ? 141.138 110.818 145.565 1.00 26.50  ? 411 TYR D CE2 1 
ATOM   10925 C CZ  . TYR D 1 446 ? 140.014 110.605 144.802 1.00 28.21  ? 411 TYR D CZ  1 
ATOM   10926 O OH  . TYR D 1 446 ? 139.695 111.485 143.794 1.00 33.64  ? 411 TYR D OH  1 
ATOM   10927 N N   . TRP D 1 447 ? 144.055 107.540 147.389 1.00 37.90  ? 412 TRP D N   1 
ATOM   10928 C CA  . TRP D 1 447 ? 145.219 108.077 146.693 1.00 38.81  ? 412 TRP D CA  1 
ATOM   10929 C C   . TRP D 1 447 ? 146.087 106.969 146.107 1.00 41.92  ? 412 TRP D C   1 
ATOM   10930 O O   . TRP D 1 447 ? 146.572 107.091 144.977 1.00 46.62  ? 412 TRP D O   1 
ATOM   10931 C CB  . TRP D 1 447 ? 146.034 108.953 147.643 1.00 35.57  ? 412 TRP D CB  1 
ATOM   10932 C CG  . TRP D 1 447 ? 145.360 110.252 147.977 1.00 33.87  ? 412 TRP D CG  1 
ATOM   10933 C CD1 . TRP D 1 447 ? 144.894 110.637 149.198 1.00 34.78  ? 412 TRP D CD1 1 
ATOM   10934 C CD2 . TRP D 1 447 ? 145.061 111.326 147.078 1.00 32.31  ? 412 TRP D CD2 1 
ATOM   10935 N NE1 . TRP D 1 447 ? 144.330 111.885 149.120 1.00 33.53  ? 412 TRP D NE1 1 
ATOM   10936 C CE2 . TRP D 1 447 ? 144.418 112.330 147.828 1.00 33.82  ? 412 TRP D CE2 1 
ATOM   10937 C CE3 . TRP D 1 447 ? 145.275 111.538 145.714 1.00 29.81  ? 412 TRP D CE3 1 
ATOM   10938 C CZ2 . TRP D 1 447 ? 143.991 113.526 147.261 1.00 31.75  ? 412 TRP D CZ2 1 
ATOM   10939 C CZ3 . TRP D 1 447 ? 144.850 112.727 145.154 1.00 30.67  ? 412 TRP D CZ3 1 
ATOM   10940 C CH2 . TRP D 1 447 ? 144.215 113.705 145.925 1.00 30.35  ? 412 TRP D CH2 1 
ATOM   10941 N N   . ALA D 1 448 ? 146.291 105.880 146.853 1.00 39.28  ? 413 ALA D N   1 
ATOM   10942 C CA  . ALA D 1 448 ? 147.059 104.755 146.323 1.00 41.77  ? 413 ALA D CA  1 
ATOM   10943 C C   . ALA D 1 448 ? 146.412 104.154 145.082 1.00 45.03  ? 413 ALA D C   1 
ATOM   10944 O O   . ALA D 1 448 ? 147.112 103.606 144.223 1.00 48.22  ? 413 ALA D O   1 
ATOM   10945 C CB  . ALA D 1 448 ? 147.239 103.682 147.396 1.00 40.17  ? 413 ALA D CB  1 
ATOM   10946 N N   . THR D 1 449 ? 145.087 104.247 144.963 1.00 42.32  ? 414 THR D N   1 
ATOM   10947 C CA  . THR D 1 449 ? 144.408 103.677 143.804 1.00 42.86  ? 414 THR D CA  1 
ATOM   10948 C C   . THR D 1 449 ? 144.664 104.509 142.553 1.00 43.65  ? 414 THR D C   1 
ATOM   10949 O O   . THR D 1 449 ? 144.966 103.966 141.484 1.00 44.80  ? 414 THR D O   1 
ATOM   10950 C CB  . THR D 1 449 ? 142.908 103.566 144.079 1.00 42.74  ? 414 THR D CB  1 
ATOM   10951 O OG1 . THR D 1 449 ? 142.670 102.496 145.001 1.00 42.02  ? 414 THR D OG1 1 
ATOM   10952 C CG2 . THR D 1 449 ? 142.142 103.298 142.793 1.00 42.34  ? 414 THR D CG2 1 
ATOM   10953 N N   . TYR D 1 450 ? 144.559 105.831 142.668 1.00 40.73  ? 415 TYR D N   1 
ATOM   10954 C CA  . TYR D 1 450 ? 144.600 106.698 141.498 1.00 41.84  ? 415 TYR D CA  1 
ATOM   10955 C C   . TYR D 1 450 ? 145.995 107.224 141.192 1.00 44.17  ? 415 TYR D C   1 
ATOM   10956 O O   . TYR D 1 450 ? 146.289 107.531 140.031 1.00 44.55  ? 415 TYR D O   1 
ATOM   10957 C CB  . TYR D 1 450 ? 143.637 107.873 141.681 1.00 41.31  ? 415 TYR D CB  1 
ATOM   10958 C CG  . TYR D 1 450 ? 142.180 107.488 141.598 1.00 37.06  ? 415 TYR D CG  1 
ATOM   10959 C CD1 . TYR D 1 450 ? 141.594 107.185 140.378 1.00 37.94  ? 415 TYR D CD1 1 
ATOM   10960 C CD2 . TYR D 1 450 ? 141.390 107.427 142.736 1.00 35.41  ? 415 TYR D CD2 1 
ATOM   10961 C CE1 . TYR D 1 450 ? 140.263 106.833 140.293 1.00 35.30  ? 415 TYR D CE1 1 
ATOM   10962 C CE2 . TYR D 1 450 ? 140.057 107.075 142.661 1.00 33.66  ? 415 TYR D CE2 1 
ATOM   10963 C CZ  . TYR D 1 450 ? 139.499 106.779 141.436 1.00 32.19  ? 415 TYR D CZ  1 
ATOM   10964 O OH  . TYR D 1 450 ? 138.173 106.429 141.351 1.00 31.88  ? 415 TYR D OH  1 
ATOM   10965 N N   . LEU D 1 451 ? 146.857 107.340 142.196 1.00 42.27  ? 416 LEU D N   1 
ATOM   10966 C CA  . LEU D 1 451 ? 148.225 107.788 141.967 1.00 42.06  ? 416 LEU D CA  1 
ATOM   10967 C C   . LEU D 1 451 ? 149.114 106.623 141.548 1.00 45.68  ? 416 LEU D C   1 
ATOM   10968 O O   . LEU D 1 451 ? 149.183 106.276 140.369 1.00 53.65  ? 416 LEU D O   1 
ATOM   10969 C CB  . LEU D 1 451 ? 148.791 108.458 143.220 1.00 38.47  ? 416 LEU D CB  1 
ATOM   10970 C CG  . LEU D 1 451 ? 148.162 109.796 143.605 1.00 36.57  ? 416 LEU D CG  1 
ATOM   10971 C CD1 . LEU D 1 451 ? 148.871 110.393 144.809 1.00 36.74  ? 416 LEU D CD1 1 
ATOM   10972 C CD2 . LEU D 1 451 ? 148.190 110.757 142.429 1.00 36.53  ? 416 LEU D CD2 1 
ATOM   10973 N N   . MET E 2 34  ? 112.345 147.737 76.870  1.00 82.23  ? 9   MET E N   1 
ATOM   10974 C CA  . MET E 2 34  ? 113.220 147.123 77.861  1.00 84.34  ? 9   MET E CA  1 
ATOM   10975 C C   . MET E 2 34  ? 114.630 146.931 77.312  1.00 90.38  ? 9   MET E C   1 
ATOM   10976 O O   . MET E 2 34  ? 115.611 147.106 78.036  1.00 94.60  ? 9   MET E O   1 
ATOM   10977 C CB  . MET E 2 34  ? 112.648 145.785 78.332  1.00 83.15  ? 9   MET E CB  1 
ATOM   10978 C CG  . MET E 2 34  ? 111.363 145.915 79.133  1.00 88.45  ? 9   MET E CG  1 
ATOM   10979 S SD  . MET E 2 34  ? 110.862 144.364 79.903  1.00 101.00 ? 9   MET E SD  1 
ATOM   10980 C CE  . MET E 2 34  ? 111.978 144.314 81.302  1.00 88.42  ? 9   MET E CE  1 
ATOM   10981 N N   . SER E 2 35  ? 114.732 146.562 76.032  1.00 88.38  ? 10  SER E N   1 
ATOM   10982 C CA  . SER E 2 35  ? 116.050 146.415 75.424  1.00 89.40  ? 10  SER E CA  1 
ATOM   10983 C C   . SER E 2 35  ? 116.772 147.752 75.342  1.00 92.11  ? 10  SER E C   1 
ATOM   10984 O O   . SER E 2 35  ? 118.004 147.796 75.428  1.00 92.36  ? 10  SER E O   1 
ATOM   10985 C CB  . SER E 2 35  ? 115.926 145.788 74.035  1.00 93.66  ? 10  SER E CB  1 
ATOM   10986 O OG  . SER E 2 35  ? 115.194 146.628 73.159  1.00 94.70  ? 10  SER E OG  1 
ATOM   10987 N N   . PHE E 2 36  ? 116.025 148.845 75.161  1.00 94.27  ? 11  PHE E N   1 
ATOM   10988 C CA  . PHE E 2 36  ? 116.635 150.169 75.105  1.00 95.75  ? 11  PHE E CA  1 
ATOM   10989 C C   . PHE E 2 36  ? 117.379 150.480 76.398  1.00 93.98  ? 11  PHE E C   1 
ATOM   10990 O O   . PHE E 2 36  ? 118.498 151.008 76.372  1.00 93.94  ? 11  PHE E O   1 
ATOM   10991 C CB  . PHE E 2 36  ? 115.573 151.231 74.824  1.00 97.56  ? 11  PHE E CB  1 
ATOM   10992 C CG  . PHE E 2 36  ? 116.030 152.633 75.108  1.00 100.02 ? 11  PHE E CG  1 
ATOM   10993 C CD1 . PHE E 2 36  ? 117.073 153.195 74.389  1.00 94.96  ? 11  PHE E CD1 1 
ATOM   10994 C CD2 . PHE E 2 36  ? 115.414 153.391 76.089  1.00 99.10  ? 11  PHE E CD2 1 
ATOM   10995 C CE1 . PHE E 2 36  ? 117.496 154.485 74.647  1.00 91.56  ? 11  PHE E CE1 1 
ATOM   10996 C CE2 . PHE E 2 36  ? 115.832 154.683 76.350  1.00 98.41  ? 11  PHE E CE2 1 
ATOM   10997 C CZ  . PHE E 2 36  ? 116.874 155.230 75.629  1.00 95.33  ? 11  PHE E CZ  1 
ATOM   10998 N N   . VAL E 2 37  ? 116.767 150.159 77.540  1.00 90.22  ? 12  VAL E N   1 
ATOM   10999 C CA  . VAL E 2 37  ? 117.437 150.319 78.828  1.00 88.57  ? 12  VAL E CA  1 
ATOM   11000 C C   . VAL E 2 37  ? 118.631 149.380 78.926  1.00 89.22  ? 12  VAL E C   1 
ATOM   11001 O O   . VAL E 2 37  ? 119.697 149.759 79.425  1.00 91.91  ? 12  VAL E O   1 
ATOM   11002 C CB  . VAL E 2 37  ? 116.437 150.093 79.978  1.00 85.04  ? 12  VAL E CB  1 
ATOM   11003 C CG1 . VAL E 2 37  ? 117.157 150.051 81.318  1.00 86.07  ? 12  VAL E CG1 1 
ATOM   11004 C CG2 . VAL E 2 37  ? 115.372 151.177 79.974  1.00 81.36  ? 12  VAL E CG2 1 
ATOM   11005 N N   . LYS E 2 38  ? 118.474 148.138 78.460  1.00 87.72  ? 13  LYS E N   1 
ATOM   11006 C CA  . LYS E 2 38  ? 119.590 147.198 78.485  1.00 85.33  ? 13  LYS E CA  1 
ATOM   11007 C C   . LYS E 2 38  ? 120.759 147.709 77.651  1.00 87.32  ? 13  LYS E C   1 
ATOM   11008 O O   . LYS E 2 38  ? 121.918 147.616 78.071  1.00 87.20  ? 13  LYS E O   1 
ATOM   11009 C CB  . LYS E 2 38  ? 119.133 145.830 77.978  1.00 87.81  ? 13  LYS E CB  1 
ATOM   11010 C CG  . LYS E 2 38  ? 120.238 144.788 77.909  1.00 96.24  ? 13  LYS E CG  1 
ATOM   11011 C CD  . LYS E 2 38  ? 119.732 143.488 77.301  1.00 94.33  ? 13  LYS E CD  1 
ATOM   11012 C CE  . LYS E 2 38  ? 120.875 142.524 77.018  1.00 78.23  ? 13  LYS E CE  1 
ATOM   11013 N NZ  . LYS E 2 38  ? 121.635 142.173 78.251  1.00 74.61  ? 13  LYS E NZ  1 
ATOM   11014 N N   . GLU E 2 39  ? 120.474 148.254 76.466  1.00 90.33  ? 14  GLU E N   1 
ATOM   11015 C CA  . GLU E 2 39  ? 121.535 148.809 75.631  1.00 89.71  ? 14  GLU E CA  1 
ATOM   11016 C C   . GLU E 2 39  ? 122.208 149.996 76.307  1.00 86.09  ? 14  GLU E C   1 
ATOM   11017 O O   . GLU E 2 39  ? 123.433 150.152 76.229  1.00 86.88  ? 14  GLU E O   1 
ATOM   11018 C CB  . GLU E 2 39  ? 120.976 149.207 74.266  1.00 96.29  ? 14  GLU E CB  1 
ATOM   11019 C CG  . GLU E 2 39  ? 120.576 148.022 73.403  1.00 100.95 ? 14  GLU E CG  1 
ATOM   11020 C CD  . GLU E 2 39  ? 119.843 148.436 72.146  1.00 107.60 ? 14  GLU E CD  1 
ATOM   11021 O OE1 . GLU E 2 39  ? 119.580 149.646 71.982  1.00 110.00 ? 14  GLU E OE1 1 
ATOM   11022 O OE2 . GLU E 2 39  ? 119.527 147.552 71.322  1.00 106.09 ? 14  GLU E OE2 1 
ATOM   11023 N N   . THR E 2 40  ? 121.420 150.856 76.958  1.00 85.89  ? 15  THR E N   1 
ATOM   11024 C CA  . THR E 2 40  ? 121.975 152.032 77.625  1.00 84.65  ? 15  THR E CA  1 
ATOM   11025 C C   . THR E 2 40  ? 122.988 151.635 78.693  1.00 81.78  ? 15  THR E C   1 
ATOM   11026 O O   . THR E 2 40  ? 124.093 152.187 78.755  1.00 83.81  ? 15  THR E O   1 
ATOM   11027 C CB  . THR E 2 40  ? 120.849 152.865 78.241  1.00 84.26  ? 15  THR E CB  1 
ATOM   11028 O OG1 . THR E 2 40  ? 119.995 153.363 77.205  1.00 88.04  ? 15  THR E OG1 1 
ATOM   11029 C CG2 . THR E 2 40  ? 121.421 154.035 79.027  1.00 80.32  ? 15  THR E CG2 1 
ATOM   11030 N N   . VAL E 2 41  ? 122.622 150.678 79.548  1.00 77.24  ? 16  VAL E N   1 
ATOM   11031 C CA  . VAL E 2 41  ? 123.509 150.250 80.627  1.00 73.73  ? 16  VAL E CA  1 
ATOM   11032 C C   . VAL E 2 41  ? 124.793 149.649 80.066  1.00 77.32  ? 16  VAL E C   1 
ATOM   11033 O O   . VAL E 2 41  ? 125.882 149.857 80.614  1.00 77.49  ? 16  VAL E O   1 
ATOM   11034 C CB  . VAL E 2 41  ? 122.775 149.266 81.557  1.00 75.03  ? 16  VAL E CB  1 
ATOM   11035 C CG1 . VAL E 2 41  ? 123.701 148.780 82.660  1.00 76.24  ? 16  VAL E CG1 1 
ATOM   11036 C CG2 . VAL E 2 41  ? 121.538 149.924 82.147  1.00 67.90  ? 16  VAL E CG2 1 
ATOM   11037 N N   . ASP E 2 42  ? 124.688 148.895 78.968  1.00 82.38  ? 17  ASP E N   1 
ATOM   11038 C CA  . ASP E 2 42  ? 125.880 148.303 78.364  1.00 83.20  ? 17  ASP E CA  1 
ATOM   11039 C C   . ASP E 2 42  ? 126.863 149.373 77.906  1.00 82.76  ? 17  ASP E C   1 
ATOM   11040 O O   . ASP E 2 42  ? 128.079 149.215 78.065  1.00 84.94  ? 17  ASP E O   1 
ATOM   11041 C CB  . ASP E 2 42  ? 125.488 147.407 77.189  1.00 84.53  ? 17  ASP E CB  1 
ATOM   11042 C CG  . ASP E 2 42  ? 124.767 146.148 77.628  1.00 82.91  ? 17  ASP E CG  1 
ATOM   11043 O OD1 . ASP E 2 42  ? 125.228 145.503 78.593  1.00 83.08  ? 17  ASP E OD1 1 
ATOM   11044 O OD2 . ASP E 2 42  ? 123.747 145.797 76.999  1.00 79.05  ? 17  ASP E OD2 1 
ATOM   11045 N N   . LYS E 2 43  ? 126.359 150.463 77.321  1.00 82.56  ? 18  LYS E N   1 
ATOM   11046 C CA  . LYS E 2 43  ? 127.243 151.530 76.860  1.00 83.75  ? 18  LYS E CA  1 
ATOM   11047 C C   . LYS E 2 43  ? 128.032 152.129 78.019  1.00 80.70  ? 18  LYS E C   1 
ATOM   11048 O O   . LYS E 2 43  ? 129.233 152.393 77.894  1.00 83.37  ? 18  LYS E O   1 
ATOM   11049 C CB  . LYS E 2 43  ? 126.435 152.611 76.144  1.00 82.35  ? 18  LYS E CB  1 
ATOM   11050 C CG  . LYS E 2 43  ? 127.272 153.775 75.636  1.00 82.21  ? 18  LYS E CG  1 
ATOM   11051 C CD  . LYS E 2 43  ? 126.398 154.895 75.097  1.00 78.74  ? 18  LYS E CD  1 
ATOM   11052 C CE  . LYS E 2 43  ? 127.229 156.115 74.731  1.00 69.80  ? 18  LYS E CE  1 
ATOM   11053 N NZ  . LYS E 2 43  ? 126.384 157.255 74.282  1.00 70.31  ? 18  LYS E NZ  1 
ATOM   11054 N N   . LEU E 2 44  ? 127.363 152.361 79.151  1.00 73.83  ? 19  LEU E N   1 
ATOM   11055 C CA  . LEU E 2 44  ? 128.006 153.001 80.295  1.00 72.73  ? 19  LEU E CA  1 
ATOM   11056 C C   . LEU E 2 44  ? 129.182 152.179 80.809  1.00 75.97  ? 19  LEU E C   1 
ATOM   11057 O O   . LEU E 2 44  ? 130.250 152.727 81.106  1.00 81.06  ? 19  LEU E O   1 
ATOM   11058 C CB  . LEU E 2 44  ? 126.985 153.235 81.406  1.00 75.81  ? 19  LEU E CB  1 
ATOM   11059 C CG  . LEU E 2 44  ? 125.783 154.098 81.020  1.00 75.30  ? 19  LEU E CG  1 
ATOM   11060 C CD1 . LEU E 2 44  ? 124.788 154.181 82.166  1.00 72.08  ? 19  LEU E CD1 1 
ATOM   11061 C CD2 . LEU E 2 44  ? 126.238 155.486 80.595  1.00 68.37  ? 19  LEU E CD2 1 
ATOM   11062 N N   . LEU E 2 45  ? 129.007 150.864 80.917  1.00 76.11  ? 20  LEU E N   1 
ATOM   11063 C CA  . LEU E 2 45  ? 130.032 149.987 81.467  1.00 75.96  ? 20  LEU E CA  1 
ATOM   11064 C C   . LEU E 2 45  ? 131.071 149.555 80.442  1.00 74.58  ? 20  LEU E C   1 
ATOM   11065 O O   . LEU E 2 45  ? 132.052 148.906 80.818  1.00 65.33  ? 20  LEU E O   1 
ATOM   11066 C CB  . LEU E 2 45  ? 129.379 148.745 82.079  1.00 77.84  ? 20  LEU E CB  1 
ATOM   11067 C CG  . LEU E 2 45  ? 128.380 149.002 83.208  1.00 75.67  ? 20  LEU E CG  1 
ATOM   11068 C CD1 . LEU E 2 45  ? 127.745 147.702 83.675  1.00 70.16  ? 20  LEU E CD1 1 
ATOM   11069 C CD2 . LEU E 2 45  ? 129.061 149.709 84.359  1.00 67.58  ? 20  LEU E CD2 1 
ATOM   11070 N N   . LYS E 2 46  ? 130.891 149.901 79.170  1.00 83.18  ? 21  LYS E N   1 
ATOM   11071 C CA  . LYS E 2 46  ? 131.863 149.565 78.134  1.00 85.58  ? 21  LYS E CA  1 
ATOM   11072 C C   . LYS E 2 46  ? 133.065 150.492 78.267  1.00 83.15  ? 21  LYS E C   1 
ATOM   11073 O O   . LYS E 2 46  ? 132.955 151.703 78.048  1.00 75.84  ? 21  LYS E O   1 
ATOM   11074 C CB  . LYS E 2 46  ? 131.229 149.679 76.751  1.00 85.34  ? 21  LYS E CB  1 
ATOM   11075 C CG  . LYS E 2 46  ? 132.161 149.312 75.610  1.00 85.25  ? 21  LYS E CG  1 
ATOM   11076 C CD  . LYS E 2 46  ? 131.472 149.464 74.264  1.00 88.57  ? 21  LYS E CD  1 
ATOM   11077 C CE  . LYS E 2 46  ? 132.416 149.134 73.120  1.00 99.10  ? 21  LYS E CE  1 
ATOM   11078 N NZ  . LYS E 2 46  ? 131.782 149.370 71.795  1.00 108.36 ? 21  LYS E NZ  1 
ATOM   11079 N N   . GLY E 2 47  ? 134.214 149.922 78.624  1.00 88.12  ? 22  GLY E N   1 
ATOM   11080 C CA  . GLY E 2 47  ? 135.415 150.697 78.858  1.00 87.33  ? 22  GLY E CA  1 
ATOM   11081 C C   . GLY E 2 47  ? 135.485 151.386 80.201  1.00 92.08  ? 22  GLY E C   1 
ATOM   11082 O O   . GLY E 2 47  ? 136.428 152.149 80.438  1.00 94.79  ? 22  GLY E O   1 
ATOM   11083 N N   . TYR E 2 48  ? 134.519 151.146 81.085  1.00 88.53  ? 23  TYR E N   1 
ATOM   11084 C CA  . TYR E 2 48  ? 134.533 151.760 82.406  1.00 80.40  ? 23  TYR E CA  1 
ATOM   11085 C C   . TYR E 2 48  ? 135.690 151.215 83.235  1.00 76.06  ? 23  TYR E C   1 
ATOM   11086 O O   . TYR E 2 48  ? 135.875 149.999 83.340  1.00 73.79  ? 23  TYR E O   1 
ATOM   11087 C CB  . TYR E 2 48  ? 133.199 151.488 83.102  1.00 74.46  ? 23  TYR E CB  1 
ATOM   11088 C CG  . TYR E 2 48  ? 132.967 152.228 84.401  1.00 65.88  ? 23  TYR E CG  1 
ATOM   11089 C CD1 . TYR E 2 48  ? 133.441 151.720 85.604  1.00 62.97  ? 23  TYR E CD1 1 
ATOM   11090 C CD2 . TYR E 2 48  ? 132.252 153.416 84.430  1.00 64.90  ? 23  TYR E CD2 1 
ATOM   11091 C CE1 . TYR E 2 48  ? 133.222 152.382 86.795  1.00 62.31  ? 23  TYR E CE1 1 
ATOM   11092 C CE2 . TYR E 2 48  ? 132.029 154.086 85.618  1.00 64.06  ? 23  TYR E CE2 1 
ATOM   11093 C CZ  . TYR E 2 48  ? 132.516 153.563 86.797  1.00 63.18  ? 23  TYR E CZ  1 
ATOM   11094 O OH  . TYR E 2 48  ? 132.299 154.223 87.984  1.00 59.93  ? 23  TYR E OH  1 
ATOM   11095 N N   . ASP E 2 49  ? 136.470 152.120 83.826  1.00 73.38  ? 24  ASP E N   1 
ATOM   11096 C CA  . ASP E 2 49  ? 137.626 151.759 84.639  1.00 75.46  ? 24  ASP E CA  1 
ATOM   11097 C C   . ASP E 2 49  ? 137.254 151.936 86.108  1.00 70.02  ? 24  ASP E C   1 
ATOM   11098 O O   . ASP E 2 49  ? 137.069 153.064 86.574  1.00 65.10  ? 24  ASP E O   1 
ATOM   11099 C CB  . ASP E 2 49  ? 138.840 152.606 84.265  1.00 75.39  ? 24  ASP E CB  1 
ATOM   11100 C CG  . ASP E 2 49  ? 140.148 151.957 84.669  1.00 73.52  ? 24  ASP E CG  1 
ATOM   11101 O OD1 . ASP E 2 49  ? 140.111 150.834 85.215  1.00 69.14  ? 24  ASP E OD1 1 
ATOM   11102 O OD2 . ASP E 2 49  ? 141.212 152.564 84.432  1.00 77.67  ? 24  ASP E OD2 1 
ATOM   11103 N N   . ILE E 2 50  ? 137.150 150.824 86.837  1.00 65.63  ? 25  ILE E N   1 
ATOM   11104 C CA  . ILE E 2 50  ? 136.743 150.905 88.236  1.00 58.25  ? 25  ILE E CA  1 
ATOM   11105 C C   . ILE E 2 50  ? 137.896 151.224 89.180  1.00 60.27  ? 25  ILE E C   1 
ATOM   11106 O O   . ILE E 2 50  ? 137.649 151.600 90.332  1.00 63.21  ? 25  ILE E O   1 
ATOM   11107 C CB  . ILE E 2 50  ? 136.076 149.593 88.678  1.00 57.34  ? 25  ILE E CB  1 
ATOM   11108 C CG1 . ILE E 2 50  ? 137.045 148.423 88.508  1.00 51.09  ? 25  ILE E CG1 1 
ATOM   11109 C CG2 . ILE E 2 50  ? 134.807 149.346 87.880  1.00 59.07  ? 25  ILE E CG2 1 
ATOM   11110 C CD1 . ILE E 2 50  ? 136.497 147.101 88.991  1.00 49.27  ? 25  ILE E CD1 1 
ATOM   11111 N N   . ARG E 2 51  ? 139.146 151.075 88.740  1.00 60.29  ? 26  ARG E N   1 
ATOM   11112 C CA  . ARG E 2 51  ? 140.282 151.405 89.593  1.00 64.15  ? 26  ARG E CA  1 
ATOM   11113 C C   . ARG E 2 51  ? 140.579 152.897 89.666  1.00 63.37  ? 26  ARG E C   1 
ATOM   11114 O O   . ARG E 2 51  ? 141.398 153.306 90.496  1.00 61.63  ? 26  ARG E O   1 
ATOM   11115 C CB  . ARG E 2 51  ? 141.529 150.663 89.112  1.00 59.43  ? 26  ARG E CB  1 
ATOM   11116 C CG  . ARG E 2 51  ? 141.404 149.154 89.163  1.00 55.69  ? 26  ARG E CG  1 
ATOM   11117 C CD  . ARG E 2 51  ? 142.580 148.496 88.474  1.00 57.00  ? 26  ARG E CD  1 
ATOM   11118 N NE  . ARG E 2 51  ? 142.665 148.896 87.074  1.00 63.54  ? 26  ARG E NE  1 
ATOM   11119 C CZ  . ARG E 2 51  ? 143.464 148.328 86.182  1.00 66.13  ? 26  ARG E CZ  1 
ATOM   11120 N NH1 . ARG E 2 51  ? 144.243 147.309 86.503  1.00 73.61  ? 26  ARG E NH1 1 
ATOM   11121 N NH2 . ARG E 2 51  ? 143.477 148.791 84.935  1.00 56.82  ? 26  ARG E NH2 1 
ATOM   11122 N N   . LEU E 2 52  ? 139.944 153.715 88.833  1.00 62.73  ? 27  LEU E N   1 
ATOM   11123 C CA  . LEU E 2 52  ? 140.189 155.150 88.793  1.00 62.50  ? 27  LEU E CA  1 
ATOM   11124 C C   . LEU E 2 52  ? 138.947 155.907 89.240  1.00 61.51  ? 27  LEU E C   1 
ATOM   11125 O O   . LEU E 2 52  ? 137.849 155.666 88.728  1.00 62.75  ? 27  LEU E O   1 
ATOM   11126 C CB  . LEU E 2 52  ? 140.617 155.599 87.396  1.00 62.61  ? 27  LEU E CB  1 
ATOM   11127 C CG  . LEU E 2 52  ? 141.847 154.879 86.842  1.00 60.98  ? 27  LEU E CG  1 
ATOM   11128 C CD1 . LEU E 2 52  ? 142.236 155.445 85.485  1.00 59.67  ? 27  LEU E CD1 1 
ATOM   11129 C CD2 . LEU E 2 52  ? 143.008 154.970 87.820  1.00 57.76  ? 27  LEU E CD2 1 
ATOM   11130 N N   . ARG E 2 53  ? 139.127 156.822 90.188  1.00 57.31  ? 28  ARG E N   1 
ATOM   11131 C CA  . ARG E 2 53  ? 138.024 157.631 90.668  1.00 55.16  ? 28  ARG E CA  1 
ATOM   11132 C C   . ARG E 2 53  ? 137.574 158.612 89.586  1.00 57.25  ? 28  ARG E C   1 
ATOM   11133 O O   . ARG E 2 53  ? 138.316 158.899 88.645  1.00 59.32  ? 28  ARG E O   1 
ATOM   11134 C CB  . ARG E 2 53  ? 138.443 158.394 91.921  1.00 54.97  ? 28  ARG E CB  1 
ATOM   11135 C CG  . ARG E 2 53  ? 139.605 159.345 91.692  1.00 64.25  ? 28  ARG E CG  1 
ATOM   11136 C CD  . ARG E 2 53  ? 139.834 160.256 92.886  1.00 59.94  ? 28  ARG E CD  1 
ATOM   11137 N NE  . ARG E 2 53  ? 140.637 161.418 92.525  1.00 59.39  ? 28  ARG E NE  1 
ATOM   11138 C CZ  . ARG E 2 53  ? 140.146 162.541 92.018  1.00 57.75  ? 28  ARG E CZ  1 
ATOM   11139 N NH1 . ARG E 2 53  ? 138.858 162.673 91.750  1.00 53.82  ? 28  ARG E NH1 1 
ATOM   11140 N NH2 . ARG E 2 53  ? 140.973 163.549 91.754  1.00 59.28  ? 28  ARG E NH2 1 
ATOM   11141 N N   . PRO E 2 54  ? 136.353 159.134 89.700  1.00 53.45  ? 29  PRO E N   1 
ATOM   11142 C CA  . PRO E 2 54  ? 135.910 160.189 88.780  1.00 55.84  ? 29  PRO E CA  1 
ATOM   11143 C C   . PRO E 2 54  ? 136.818 161.409 88.833  1.00 60.23  ? 29  PRO E C   1 
ATOM   11144 O O   . PRO E 2 54  ? 137.323 161.786 89.893  1.00 62.72  ? 29  PRO E O   1 
ATOM   11145 C CB  . PRO E 2 54  ? 134.499 160.521 89.274  1.00 56.22  ? 29  PRO E CB  1 
ATOM   11146 C CG  . PRO E 2 54  ? 134.044 159.293 89.969  1.00 54.98  ? 29  PRO E CG  1 
ATOM   11147 C CD  . PRO E 2 54  ? 135.264 158.677 90.581  1.00 51.08  ? 29  PRO E CD  1 
ATOM   11148 N N   . ASP E 2 55  ? 137.014 162.027 87.667  1.00 60.73  ? 30  ASP E N   1 
ATOM   11149 C CA  . ASP E 2 55  ? 137.873 163.202 87.523  1.00 66.14  ? 30  ASP E CA  1 
ATOM   11150 C C   . ASP E 2 55  ? 139.271 162.947 88.081  1.00 64.45  ? 30  ASP E C   1 
ATOM   11151 O O   . ASP E 2 55  ? 139.832 163.761 88.818  1.00 62.13  ? 30  ASP E O   1 
ATOM   11152 C CB  . ASP E 2 55  ? 137.237 164.429 88.177  1.00 62.74  ? 30  ASP E CB  1 
ATOM   11153 C CG  . ASP E 2 55  ? 135.966 164.866 87.479  1.00 61.55  ? 30  ASP E CG  1 
ATOM   11154 O OD1 . ASP E 2 55  ? 135.439 164.083 86.661  1.00 69.94  ? 30  ASP E OD1 1 
ATOM   11155 O OD2 . ASP E 2 55  ? 135.495 165.992 87.745  1.00 57.15  ? 30  ASP E OD2 1 
ATOM   11156 N N   . PHE E 2 56  ? 139.826 161.786 87.734  1.00 61.26  ? 31  PHE E N   1 
ATOM   11157 C CA  . PHE E 2 56  ? 141.164 161.424 88.183  1.00 60.26  ? 31  PHE E CA  1 
ATOM   11158 C C   . PHE E 2 56  ? 142.155 162.503 87.766  1.00 64.93  ? 31  PHE E C   1 
ATOM   11159 O O   . PHE E 2 56  ? 142.218 162.892 86.596  1.00 65.84  ? 31  PHE E O   1 
ATOM   11160 C CB  . PHE E 2 56  ? 141.571 160.065 87.614  1.00 57.82  ? 31  PHE E CB  1 
ATOM   11161 C CG  . PHE E 2 56  ? 142.784 159.467 88.276  1.00 60.87  ? 31  PHE E CG  1 
ATOM   11162 C CD1 . PHE E 2 56  ? 144.053 159.962 88.018  1.00 59.11  ? 31  PHE E CD1 1 
ATOM   11163 C CD2 . PHE E 2 56  ? 142.651 158.420 89.171  1.00 65.44  ? 31  PHE E CD2 1 
ATOM   11164 C CE1 . PHE E 2 56  ? 145.163 159.415 88.629  1.00 62.82  ? 31  PHE E CE1 1 
ATOM   11165 C CE2 . PHE E 2 56  ? 143.758 157.871 89.787  1.00 66.37  ? 31  PHE E CE2 1 
ATOM   11166 C CZ  . PHE E 2 56  ? 145.015 158.369 89.515  1.00 66.08  ? 31  PHE E CZ  1 
ATOM   11167 N N   . GLY E 2 57  ? 142.931 162.985 88.736  1.00 65.44  ? 32  GLY E N   1 
ATOM   11168 C CA  . GLY E 2 57  ? 143.857 164.071 88.516  1.00 58.66  ? 32  GLY E CA  1 
ATOM   11169 C C   . GLY E 2 57  ? 143.218 165.441 88.515  1.00 57.51  ? 32  GLY E C   1 
ATOM   11170 O O   . GLY E 2 57  ? 143.941 166.445 88.466  1.00 54.14  ? 32  GLY E O   1 
ATOM   11171 N N   . GLY E 2 58  ? 141.890 165.517 88.567  1.00 60.83  ? 33  GLY E N   1 
ATOM   11172 C CA  . GLY E 2 58  ? 141.184 166.773 88.615  1.00 64.88  ? 33  GLY E CA  1 
ATOM   11173 C C   . GLY E 2 58  ? 140.815 167.129 90.040  1.00 63.84  ? 33  GLY E C   1 
ATOM   11174 O O   . GLY E 2 58  ? 141.463 166.693 90.997  1.00 62.61  ? 33  GLY E O   1 
ATOM   11175 N N   . PRO E 2 59  ? 139.773 167.941 90.211  1.00 63.87  ? 34  PRO E N   1 
ATOM   11176 C CA  . PRO E 2 59  ? 139.326 168.274 91.561  1.00 61.40  ? 34  PRO E CA  1 
ATOM   11177 C C   . PRO E 2 59  ? 138.878 167.030 92.300  1.00 63.48  ? 34  PRO E C   1 
ATOM   11178 O O   . PRO E 2 59  ? 138.414 166.053 91.684  1.00 68.48  ? 34  PRO E O   1 
ATOM   11179 C CB  . PRO E 2 59  ? 138.155 169.238 91.319  1.00 57.58  ? 34  PRO E CB  1 
ATOM   11180 C CG  . PRO E 2 59  ? 138.338 169.739 89.925  1.00 61.15  ? 34  PRO E CG  1 
ATOM   11181 C CD  . PRO E 2 59  ? 138.981 168.621 89.174  1.00 63.41  ? 34  PRO E CD  1 
ATOM   11182 N N   . PRO E 2 60  ? 139.014 167.013 93.627  1.00 58.65  ? 35  PRO E N   1 
ATOM   11183 C CA  . PRO E 2 60  ? 138.593 165.836 94.396  1.00 55.35  ? 35  PRO E CA  1 
ATOM   11184 C C   . PRO E 2 60  ? 137.101 165.578 94.254  1.00 52.65  ? 35  PRO E C   1 
ATOM   11185 O O   . PRO E 2 60  ? 136.295 166.505 94.146  1.00 51.48  ? 35  PRO E O   1 
ATOM   11186 C CB  . PRO E 2 60  ? 138.965 166.202 95.837  1.00 57.32  ? 35  PRO E CB  1 
ATOM   11187 C CG  . PRO E 2 60  ? 138.969 167.687 95.858  1.00 61.77  ? 35  PRO E CG  1 
ATOM   11188 C CD  . PRO E 2 60  ? 139.433 168.124 94.497  1.00 59.95  ? 35  PRO E CD  1 
ATOM   11189 N N   . VAL E 2 61  ? 136.737 164.300 94.248  1.00 52.62  ? 36  VAL E N   1 
ATOM   11190 C CA  . VAL E 2 61  ? 135.331 163.913 94.192  1.00 48.87  ? 36  VAL E CA  1 
ATOM   11191 C C   . VAL E 2 61  ? 134.699 164.104 95.567  1.00 45.15  ? 36  VAL E C   1 
ATOM   11192 O O   . VAL E 2 61  ? 135.225 163.634 96.584  1.00 44.67  ? 36  VAL E O   1 
ATOM   11193 C CB  . VAL E 2 61  ? 135.180 162.468 93.681  1.00 43.07  ? 36  VAL E CB  1 
ATOM   11194 C CG1 . VAL E 2 61  ? 135.801 161.460 94.639  1.00 39.68  ? 36  VAL E CG1 1 
ATOM   11195 C CG2 . VAL E 2 61  ? 133.714 162.142 93.442  1.00 41.18  ? 36  VAL E CG2 1 
ATOM   11196 N N   . CYS E 2 62  ? 133.593 164.841 95.607  1.00 46.01  ? 37  CYS E N   1 
ATOM   11197 C CA  . CYS E 2 62  ? 132.878 165.111 96.848  1.00 44.24  ? 37  CYS E CA  1 
ATOM   11198 C C   . CYS E 2 62  ? 131.856 164.007 97.086  1.00 40.46  ? 37  CYS E C   1 
ATOM   11199 O O   . CYS E 2 62  ? 130.994 163.762 96.236  1.00 38.80  ? 37  CYS E O   1 
ATOM   11200 C CB  . CYS E 2 62  ? 132.193 166.475 96.796  1.00 44.82  ? 37  CYS E CB  1 
ATOM   11201 S SG  . CYS E 2 62  ? 133.328 167.882 96.764  1.00 58.87  ? 37  CYS E SG  1 
ATOM   11202 N N   . VAL E 2 63  ? 131.949 163.345 98.236  1.00 40.70  ? 38  VAL E N   1 
ATOM   11203 C CA  . VAL E 2 63  ? 131.057 162.245 98.584  1.00 38.21  ? 38  VAL E CA  1 
ATOM   11204 C C   . VAL E 2 63  ? 130.217 162.673 99.778  1.00 36.88  ? 38  VAL E C   1 
ATOM   11205 O O   . VAL E 2 63  ? 130.756 162.983 100.847 1.00 35.24  ? 38  VAL E O   1 
ATOM   11206 C CB  . VAL E 2 63  ? 131.838 160.959 98.891  1.00 32.32  ? 38  VAL E CB  1 
ATOM   11207 C CG1 . VAL E 2 63  ? 130.882 159.818 99.189  1.00 30.18  ? 38  VAL E CG1 1 
ATOM   11208 C CG2 . VAL E 2 63  ? 132.745 160.605 97.726  1.00 31.01  ? 38  VAL E CG2 1 
ATOM   11209 N N   . GLY E 2 64  ? 128.901 162.690 99.597  1.00 36.03  ? 39  GLY E N   1 
ATOM   11210 C CA  . GLY E 2 64  ? 127.974 163.034 100.661 1.00 31.17  ? 39  GLY E CA  1 
ATOM   11211 C C   . GLY E 2 64  ? 127.337 161.794 101.262 1.00 32.85  ? 39  GLY E C   1 
ATOM   11212 O O   . GLY E 2 64  ? 126.956 160.870 100.543 1.00 34.69  ? 39  GLY E O   1 
ATOM   11213 N N   . MET E 2 65  ? 127.220 161.786 102.586 1.00 29.68  ? 40  MET E N   1 
ATOM   11214 C CA  . MET E 2 65  ? 126.740 160.614 103.301 1.00 26.39  ? 40  MET E CA  1 
ATOM   11215 C C   . MET E 2 65  ? 125.602 160.995 104.231 1.00 25.90  ? 40  MET E C   1 
ATOM   11216 O O   . MET E 2 65  ? 125.637 162.044 104.879 1.00 30.89  ? 40  MET E O   1 
ATOM   11217 C CB  . MET E 2 65  ? 127.855 159.949 104.108 1.00 22.49  ? 40  MET E CB  1 
ATOM   11218 C CG  . MET E 2 65  ? 129.063 159.570 103.285 1.00 29.21  ? 40  MET E CG  1 
ATOM   11219 S SD  . MET E 2 65  ? 130.369 158.859 104.293 1.00 54.74  ? 40  MET E SD  1 
ATOM   11220 C CE  . MET E 2 65  ? 131.666 158.710 103.073 1.00 43.54  ? 40  MET E CE  1 
ATOM   11221 N N   . ASN E 2 66  ? 124.599 160.125 104.293 1.00 22.62  ? 41  ASN E N   1 
ATOM   11222 C CA  . ASN E 2 66  ? 123.558 160.191 105.304 1.00 23.84  ? 41  ASN E CA  1 
ATOM   11223 C C   . ASN E 2 66  ? 123.292 158.776 105.788 1.00 21.41  ? 41  ASN E C   1 
ATOM   11224 O O   . ASN E 2 66  ? 123.546 157.802 105.076 1.00 23.57  ? 41  ASN E O   1 
ATOM   11225 C CB  . ASN E 2 66  ? 122.268 160.832 104.772 1.00 25.91  ? 41  ASN E CB  1 
ATOM   11226 C CG  . ASN E 2 66  ? 121.729 160.131 103.545 1.00 29.34  ? 41  ASN E CG  1 
ATOM   11227 O OD1 . ASN E 2 66  ? 121.974 160.557 102.420 1.00 33.20  ? 41  ASN E OD1 1 
ATOM   11228 N ND2 . ASN E 2 66  ? 120.976 159.059 103.757 1.00 27.50  ? 41  ASN E ND2 1 
ATOM   11229 N N   . ILE E 2 67  ? 122.781 158.662 107.007 1.00 18.45  ? 42  ILE E N   1 
ATOM   11230 C CA  . ILE E 2 67  ? 122.589 157.362 107.630 1.00 16.37  ? 42  ILE E CA  1 
ATOM   11231 C C   . ILE E 2 67  ? 121.187 157.301 108.210 1.00 20.87  ? 42  ILE E C   1 
ATOM   11232 O O   . ILE E 2 67  ? 120.720 158.257 108.838 1.00 25.21  ? 42  ILE E O   1 
ATOM   11233 C CB  . ILE E 2 67  ? 123.640 157.103 108.732 1.00 15.32  ? 42  ILE E CB  1 
ATOM   11234 C CG1 . ILE E 2 67  ? 125.056 157.297 108.189 1.00 14.75  ? 42  ILE E CG1 1 
ATOM   11235 C CG2 . ILE E 2 67  ? 123.477 155.717 109.318 1.00 15.96  ? 42  ILE E CG2 1 
ATOM   11236 C CD1 . ILE E 2 67  ? 126.136 157.118 109.231 1.00 17.01  ? 42  ILE E CD1 1 
ATOM   11237 N N   . ASP E 2 68  ? 120.514 156.177 107.990 1.00 17.15  ? 43  ASP E N   1 
ATOM   11238 C CA  . ASP E 2 68  ? 119.280 155.836 108.683 1.00 15.39  ? 43  ASP E CA  1 
ATOM   11239 C C   . ASP E 2 68  ? 119.572 154.661 109.604 1.00 15.70  ? 43  ASP E C   1 
ATOM   11240 O O   . ASP E 2 68  ? 119.909 153.570 109.132 1.00 18.34  ? 43  ASP E O   1 
ATOM   11241 C CB  . ASP E 2 68  ? 118.166 155.497 107.695 1.00 17.27  ? 43  ASP E CB  1 
ATOM   11242 C CG  . ASP E 2 68  ? 116.784 155.636 108.304 1.00 25.38  ? 43  ASP E CG  1 
ATOM   11243 O OD1 . ASP E 2 68  ? 116.639 155.400 109.521 1.00 26.85  ? 43  ASP E OD1 1 
ATOM   11244 O OD2 . ASP E 2 68  ? 115.842 155.990 107.566 1.00 30.18  ? 43  ASP E OD2 1 
ATOM   11245 N N   . ILE E 2 69  ? 119.451 154.881 110.906 1.00 16.64  ? 44  ILE E N   1 
ATOM   11246 C CA  . ILE E 2 69  ? 119.776 153.862 111.895 1.00 17.40  ? 44  ILE E CA  1 
ATOM   11247 C C   . ILE E 2 69  ? 118.544 152.996 112.115 1.00 16.75  ? 44  ILE E C   1 
ATOM   11248 O O   . ILE E 2 69  ? 117.514 153.478 112.597 1.00 18.79  ? 44  ILE E O   1 
ATOM   11249 C CB  . ILE E 2 69  ? 120.257 154.487 113.210 1.00 24.25  ? 44  ILE E CB  1 
ATOM   11250 C CG1 . ILE E 2 69  ? 121.511 155.324 112.966 1.00 24.05  ? 44  ILE E CG1 1 
ATOM   11251 C CG2 . ILE E 2 69  ? 120.550 153.400 114.222 1.00 20.78  ? 44  ILE E CG2 1 
ATOM   11252 C CD1 . ILE E 2 69  ? 122.017 156.024 114.202 1.00 27.33  ? 44  ILE E CD1 1 
ATOM   11253 N N   . ALA E 2 70  ? 118.646 151.717 111.755 1.00 15.62  ? 45  ALA E N   1 
ATOM   11254 C CA  . ALA E 2 70  ? 117.532 150.802 111.972 1.00 17.15  ? 45  ALA E CA  1 
ATOM   11255 C C   . ALA E 2 70  ? 117.404 150.413 113.439 1.00 20.93  ? 45  ALA E C   1 
ATOM   11256 O O   . ALA E 2 70  ? 116.288 150.348 113.966 1.00 25.22  ? 45  ALA E O   1 
ATOM   11257 C CB  . ALA E 2 70  ? 117.697 149.556 111.103 1.00 16.91  ? 45  ALA E CB  1 
ATOM   11258 N N   . SER E 2 71  ? 118.524 150.174 114.116 1.00 17.84  ? 46  SER E N   1 
ATOM   11259 C CA  . SER E 2 71  ? 118.508 149.780 115.518 1.00 19.20  ? 46  SER E CA  1 
ATOM   11260 C C   . SER E 2 71  ? 119.934 149.747 116.040 1.00 22.73  ? 46  SER E C   1 
ATOM   11261 O O   . SER E 2 71  ? 120.882 149.551 115.275 1.00 21.82  ? 46  SER E O   1 
ATOM   11262 C CB  . SER E 2 71  ? 117.852 148.407 115.714 1.00 18.76  ? 46  SER E CB  1 
ATOM   11263 O OG  . SER E 2 71  ? 118.588 147.394 115.053 1.00 18.21  ? 46  SER E OG  1 
ATOM   11264 N N   . ILE E 2 72  ? 120.070 149.932 117.350 1.00 27.25  ? 47  ILE E N   1 
ATOM   11265 C CA  . ILE E 2 72  ? 121.295 149.627 118.081 1.00 24.42  ? 47  ILE E CA  1 
ATOM   11266 C C   . ILE E 2 72  ? 121.011 148.429 118.973 1.00 25.42  ? 47  ILE E C   1 
ATOM   11267 O O   . ILE E 2 72  ? 120.171 148.508 119.879 1.00 29.16  ? 47  ILE E O   1 
ATOM   11268 C CB  . ILE E 2 72  ? 121.776 150.825 118.912 1.00 25.82  ? 47  ILE E CB  1 
ATOM   11269 C CG1 . ILE E 2 72  ? 122.115 152.008 118.006 1.00 25.64  ? 47  ILE E CG1 1 
ATOM   11270 C CG2 . ILE E 2 72  ? 122.986 150.443 119.743 1.00 25.81  ? 47  ILE E CG2 1 
ATOM   11271 C CD1 . ILE E 2 72  ? 122.549 153.245 118.760 1.00 28.05  ? 47  ILE E CD1 1 
ATOM   11272 N N   . ASP E 2 73  ? 121.710 147.322 118.728 1.00 25.79  ? 48  ASP E N   1 
ATOM   11273 C CA  . ASP E 2 73  ? 121.298 146.037 119.283 1.00 31.11  ? 48  ASP E CA  1 
ATOM   11274 C C   . ASP E 2 73  ? 121.994 145.751 120.611 1.00 33.25  ? 48  ASP E C   1 
ATOM   11275 O O   . ASP E 2 73  ? 121.336 145.553 121.637 1.00 41.28  ? 48  ASP E O   1 
ATOM   11276 C CB  . ASP E 2 73  ? 121.581 144.908 118.283 1.00 28.76  ? 48  ASP E CB  1 
ATOM   11277 C CG  . ASP E 2 73  ? 120.954 145.156 116.925 1.00 32.18  ? 48  ASP E CG  1 
ATOM   11278 O OD1 . ASP E 2 73  ? 119.709 145.164 116.836 1.00 31.56  ? 48  ASP E OD1 1 
ATOM   11279 O OD2 . ASP E 2 73  ? 121.707 145.331 115.944 1.00 29.37  ? 48  ASP E OD2 1 
ATOM   11280 N N   . MET E 2 74  ? 123.322 145.730 120.604 1.00 28.13  ? 49  MET E N   1 
ATOM   11281 C CA  . MET E 2 74  ? 124.111 145.425 121.787 1.00 26.37  ? 49  MET E CA  1 
ATOM   11282 C C   . MET E 2 74  ? 125.063 146.573 122.089 1.00 26.61  ? 49  MET E C   1 
ATOM   11283 O O   . MET E 2 74  ? 125.630 147.179 121.176 1.00 34.44  ? 49  MET E O   1 
ATOM   11284 C CB  . MET E 2 74  ? 124.894 144.121 121.603 1.00 29.25  ? 49  MET E CB  1 
ATOM   11285 C CG  . MET E 2 74  ? 124.019 142.931 121.238 1.00 36.85  ? 49  MET E CG  1 
ATOM   11286 S SD  . MET E 2 74  ? 124.959 141.468 120.764 1.00 77.13  ? 49  MET E SD  1 
ATOM   11287 C CE  . MET E 2 74  ? 125.835 141.122 122.287 1.00 64.14  ? 49  MET E CE  1 
ATOM   11288 N N   . VAL E 2 75  ? 125.226 146.868 123.376 1.00 24.60  ? 50  VAL E N   1 
ATOM   11289 C CA  . VAL E 2 75  ? 126.231 147.815 123.861 1.00 24.07  ? 50  VAL E CA  1 
ATOM   11290 C C   . VAL E 2 75  ? 126.927 147.103 125.017 1.00 25.56  ? 50  VAL E C   1 
ATOM   11291 O O   . VAL E 2 75  ? 126.478 147.159 126.166 1.00 32.12  ? 50  VAL E O   1 
ATOM   11292 C CB  . VAL E 2 75  ? 125.629 149.150 124.309 1.00 20.72  ? 50  VAL E CB  1 
ATOM   11293 C CG1 . VAL E 2 75  ? 126.729 150.141 124.636 1.00 22.03  ? 50  VAL E CG1 1 
ATOM   11294 C CG2 . VAL E 2 75  ? 124.717 149.714 123.235 1.00 20.92  ? 50  VAL E CG2 1 
ATOM   11295 N N   . SER E 2 76  ? 128.033 146.430 124.717 1.00 23.44  ? 51  SER E N   1 
ATOM   11296 C CA  . SER E 2 76  ? 128.687 145.533 125.658 1.00 25.51  ? 51  SER E CA  1 
ATOM   11297 C C   . SER E 2 76  ? 129.921 146.176 126.275 1.00 29.53  ? 51  SER E C   1 
ATOM   11298 O O   . SER E 2 76  ? 130.801 146.665 125.561 1.00 33.46  ? 51  SER E O   1 
ATOM   11299 C CB  . SER E 2 76  ? 129.071 144.222 124.969 1.00 31.30  ? 51  SER E CB  1 
ATOM   11300 O OG  . SER E 2 76  ? 129.862 144.461 123.820 1.00 37.11  ? 51  SER E OG  1 
ATOM   11301 N N   . GLU E 2 77  ? 129.966 146.175 127.607 1.00 30.18  ? 52  GLU E N   1 
ATOM   11302 C CA  . GLU E 2 77  ? 131.135 146.622 128.354 1.00 31.45  ? 52  GLU E CA  1 
ATOM   11303 C C   . GLU E 2 77  ? 132.253 145.588 128.319 1.00 36.36  ? 52  GLU E C   1 
ATOM   11304 O O   . GLU E 2 77  ? 133.430 145.952 128.415 1.00 35.58  ? 52  GLU E O   1 
ATOM   11305 C CB  . GLU E 2 77  ? 130.763 146.939 129.805 1.00 32.91  ? 52  GLU E CB  1 
ATOM   11306 C CG  . GLU E 2 77  ? 129.751 148.065 129.985 1.00 31.30  ? 52  GLU E CG  1 
ATOM   11307 C CD  . GLU E 2 77  ? 128.325 147.641 129.695 1.00 33.81  ? 52  GLU E CD  1 
ATOM   11308 O OE1 . GLU E 2 77  ? 128.077 146.424 129.570 1.00 36.34  ? 52  GLU E OE1 1 
ATOM   11309 O OE2 . GLU E 2 77  ? 127.451 148.527 129.593 1.00 32.44  ? 52  GLU E OE2 1 
ATOM   11310 N N   . VAL E 2 78  ? 131.904 144.305 128.191 1.00 40.51  ? 53  VAL E N   1 
ATOM   11311 C CA  . VAL E 2 78  ? 132.911 143.247 128.161 1.00 44.24  ? 53  VAL E CA  1 
ATOM   11312 C C   . VAL E 2 78  ? 133.825 143.416 126.957 1.00 38.63  ? 53  VAL E C   1 
ATOM   11313 O O   . VAL E 2 78  ? 135.055 143.402 127.079 1.00 35.94  ? 53  VAL E O   1 
ATOM   11314 C CB  . VAL E 2 78  ? 132.234 141.864 128.160 1.00 45.12  ? 53  VAL E CB  1 
ATOM   11315 C CG1 . VAL E 2 78  ? 133.270 140.764 127.986 1.00 44.23  ? 53  VAL E CG1 1 
ATOM   11316 C CG2 . VAL E 2 78  ? 131.434 141.658 129.437 1.00 41.49  ? 53  VAL E CG2 1 
ATOM   11317 N N   . ASN E 2 79  ? 133.239 143.589 125.784 1.00 32.63  ? 54  ASN E N   1 
ATOM   11318 C CA  . ASN E 2 79  ? 133.997 143.778 124.561 1.00 33.19  ? 54  ASN E CA  1 
ATOM   11319 C C   . ASN E 2 79  ? 134.332 145.238 124.293 1.00 33.31  ? 54  ASN E C   1 
ATOM   11320 O O   . ASN E 2 79  ? 135.138 145.513 123.398 1.00 29.17  ? 54  ASN E O   1 
ATOM   11321 C CB  . ASN E 2 79  ? 133.221 143.202 123.374 1.00 34.80  ? 54  ASN E CB  1 
ATOM   11322 C CG  . ASN E 2 79  ? 132.871 141.741 123.563 1.00 37.31  ? 54  ASN E CG  1 
ATOM   11323 O OD1 . ASN E 2 79  ? 132.994 141.199 124.660 1.00 36.76  ? 54  ASN E OD1 1 
ATOM   11324 N ND2 . ASN E 2 79  ? 132.429 141.096 122.491 1.00 41.67  ? 54  ASN E ND2 1 
ATOM   11325 N N   . MET E 2 80  ? 133.766 146.165 125.067 1.00 34.90  ? 55  MET E N   1 
ATOM   11326 C CA  . MET E 2 80  ? 133.965 147.602 124.884 1.00 32.08  ? 55  MET E CA  1 
ATOM   11327 C C   . MET E 2 80  ? 133.741 147.955 123.419 1.00 26.71  ? 55  MET E C   1 
ATOM   11328 O O   . MET E 2 80  ? 134.624 148.430 122.703 1.00 25.43  ? 55  MET E O   1 
ATOM   11329 C CB  . MET E 2 80  ? 135.353 148.041 125.349 1.00 30.53  ? 55  MET E CB  1 
ATOM   11330 C CG  . MET E 2 80  ? 135.513 148.142 126.848 1.00 28.35  ? 55  MET E CG  1 
ATOM   11331 S SD  . MET E 2 80  ? 137.063 148.946 127.279 1.00 46.86  ? 55  MET E SD  1 
ATOM   11332 C CE  . MET E 2 80  ? 136.945 148.948 129.060 1.00 45.52  ? 55  MET E CE  1 
ATOM   11333 N N   . ASP E 2 81  ? 132.510 147.709 122.997 1.00 25.42  ? 56  ASP E N   1 
ATOM   11334 C CA  . ASP E 2 81  ? 132.039 148.006 121.656 1.00 25.01  ? 56  ASP E CA  1 
ATOM   11335 C C   . ASP E 2 81  ? 130.524 148.127 121.712 1.00 24.44  ? 56  ASP E C   1 
ATOM   11336 O O   . ASP E 2 81  ? 129.908 147.999 122.774 1.00 25.31  ? 56  ASP E O   1 
ATOM   11337 C CB  . ASP E 2 81  ? 132.505 146.942 120.659 1.00 27.86  ? 56  ASP E CB  1 
ATOM   11338 C CG  . ASP E 2 81  ? 132.110 145.533 121.066 1.00 30.18  ? 56  ASP E CG  1 
ATOM   11339 O OD1 . ASP E 2 81  ? 131.152 145.362 121.846 1.00 31.88  ? 56  ASP E OD1 1 
ATOM   11340 O OD2 . ASP E 2 81  ? 132.772 144.583 120.599 1.00 30.61  ? 56  ASP E OD2 1 
ATOM   11341 N N   . TYR E 2 82  ? 129.925 148.376 120.555 1.00 21.92  ? 57  TYR E N   1 
ATOM   11342 C CA  . TYR E 2 82  ? 128.478 148.392 120.444 1.00 20.51  ? 57  TYR E CA  1 
ATOM   11343 C C   . TYR E 2 82  ? 128.120 147.964 119.034 1.00 19.53  ? 57  TYR E C   1 
ATOM   11344 O O   . TYR E 2 82  ? 128.909 148.127 118.101 1.00 21.66  ? 57  TYR E O   1 
ATOM   11345 C CB  . TYR E 2 82  ? 127.896 149.773 120.773 1.00 18.06  ? 57  TYR E CB  1 
ATOM   11346 C CG  . TYR E 2 82  ? 128.289 150.864 119.808 1.00 17.52  ? 57  TYR E CG  1 
ATOM   11347 C CD1 . TYR E 2 82  ? 129.497 151.530 119.943 1.00 19.78  ? 57  TYR E CD1 1 
ATOM   11348 C CD2 . TYR E 2 82  ? 127.446 151.243 118.776 1.00 18.20  ? 57  TYR E CD2 1 
ATOM   11349 C CE1 . TYR E 2 82  ? 129.860 152.530 119.069 1.00 20.88  ? 57  TYR E CE1 1 
ATOM   11350 C CE2 . TYR E 2 82  ? 127.800 152.244 117.896 1.00 19.43  ? 57  TYR E CE2 1 
ATOM   11351 C CZ  . TYR E 2 82  ? 129.008 152.884 118.048 1.00 20.75  ? 57  TYR E CZ  1 
ATOM   11352 O OH  . TYR E 2 82  ? 129.371 153.883 117.175 1.00 24.71  ? 57  TYR E OH  1 
ATOM   11353 N N   . THR E 2 83  ? 126.921 147.419 118.887 1.00 19.28  ? 58  THR E N   1 
ATOM   11354 C CA  . THR E 2 83  ? 126.432 146.983 117.591 1.00 15.14  ? 58  THR E CA  1 
ATOM   11355 C C   . THR E 2 83  ? 125.442 147.995 117.041 1.00 16.72  ? 58  THR E C   1 
ATOM   11356 O O   . THR E 2 83  ? 124.671 148.601 117.788 1.00 22.22  ? 58  THR E O   1 
ATOM   11357 C CB  . THR E 2 83  ? 125.772 145.607 117.710 1.00 20.06  ? 58  THR E CB  1 
ATOM   11358 O OG1 . THR E 2 83  ? 126.690 144.688 118.315 1.00 19.24  ? 58  THR E OG1 1 
ATOM   11359 C CG2 . THR E 2 83  ? 125.379 145.075 116.348 1.00 22.78  ? 58  THR E CG2 1 
ATOM   11360 N N   . LEU E 2 84  ? 125.473 148.166 115.724 1.00 15.44  ? 59  LEU E N   1 
ATOM   11361 C CA  . LEU E 2 84  ? 124.719 149.207 115.044 1.00 15.82  ? 59  LEU E CA  1 
ATOM   11362 C C   . LEU E 2 84  ? 124.234 148.647 113.720 1.00 18.02  ? 59  LEU E C   1 
ATOM   11363 O O   . LEU E 2 84  ? 125.046 148.202 112.904 1.00 21.71  ? 59  LEU E O   1 
ATOM   11364 C CB  . LEU E 2 84  ? 125.592 150.446 114.822 1.00 14.53  ? 59  LEU E CB  1 
ATOM   11365 C CG  . LEU E 2 84  ? 125.001 151.680 114.144 1.00 15.77  ? 59  LEU E CG  1 
ATOM   11366 C CD1 . LEU E 2 84  ? 124.076 152.421 115.081 1.00 21.32  ? 59  LEU E CD1 1 
ATOM   11367 C CD2 . LEU E 2 84  ? 126.119 152.589 113.677 1.00 15.38  ? 59  LEU E CD2 1 
ATOM   11368 N N   . THR E 2 85  ? 122.925 148.666 113.503 1.00 14.30  ? 60  THR E N   1 
ATOM   11369 C CA  . THR E 2 85  ? 122.353 148.308 112.215 1.00 12.30  ? 60  THR E CA  1 
ATOM   11370 C C   . THR E 2 85  ? 121.833 149.590 111.590 1.00 13.05  ? 60  THR E C   1 
ATOM   11371 O O   . THR E 2 85  ? 121.000 150.280 112.184 1.00 20.79  ? 60  THR E O   1 
ATOM   11372 C CB  . THR E 2 85  ? 121.233 147.279 112.364 1.00 15.06  ? 60  THR E CB  1 
ATOM   11373 O OG1 . THR E 2 85  ? 121.748 146.096 112.987 1.00 14.39  ? 60  THR E OG1 1 
ATOM   11374 C CG2 . THR E 2 85  ? 120.661 146.918 111.004 1.00 16.30  ? 60  THR E CG2 1 
ATOM   11375 N N   . MET E 2 86  ? 122.329 149.907 110.399 1.00 10.20  ? 61  MET E N   1 
ATOM   11376 C CA  . MET E 2 86  ? 122.041 151.185 109.776 1.00 11.56  ? 61  MET E CA  1 
ATOM   11377 C C   . MET E 2 86  ? 121.892 151.016 108.275 1.00 10.46  ? 61  MET E C   1 
ATOM   11378 O O   . MET E 2 86  ? 122.397 150.063 107.678 1.00 13.75  ? 61  MET E O   1 
ATOM   11379 C CB  . MET E 2 86  ? 123.137 152.211 110.072 1.00 15.02  ? 61  MET E CB  1 
ATOM   11380 C CG  . MET E 2 86  ? 124.498 151.820 109.539 1.00 15.06  ? 61  MET E CG  1 
ATOM   11381 S SD  . MET E 2 86  ? 125.798 152.914 110.128 1.00 23.08  ? 61  MET E SD  1 
ATOM   11382 C CE  . MET E 2 86  ? 127.246 151.979 109.663 1.00 13.41  ? 61  MET E CE  1 
ATOM   11383 N N   . TYR E 2 87  ? 121.185 151.962 107.675 1.00 11.34  ? 62  TYR E N   1 
ATOM   11384 C CA  . TYR E 2 87  ? 121.175 152.141 106.232 1.00 12.05  ? 62  TYR E CA  1 
ATOM   11385 C C   . TYR E 2 87  ? 122.175 153.241 105.905 1.00 14.00  ? 62  TYR E C   1 
ATOM   11386 O O   . TYR E 2 87  ? 122.022 154.380 106.359 1.00 20.08  ? 62  TYR E O   1 
ATOM   11387 C CB  . TYR E 2 87  ? 119.777 152.491 105.725 1.00 12.88  ? 62  TYR E CB  1 
ATOM   11388 C CG  . TYR E 2 87  ? 118.747 151.428 106.022 1.00 12.57  ? 62  TYR E CG  1 
ATOM   11389 C CD1 . TYR E 2 87  ? 118.132 151.358 107.263 1.00 15.88  ? 62  TYR E CD1 1 
ATOM   11390 C CD2 . TYR E 2 87  ? 118.386 150.497 105.061 1.00 13.03  ? 62  TYR E CD2 1 
ATOM   11391 C CE1 . TYR E 2 87  ? 117.192 150.389 107.540 1.00 18.25  ? 62  TYR E CE1 1 
ATOM   11392 C CE2 . TYR E 2 87  ? 117.444 149.526 105.327 1.00 17.42  ? 62  TYR E CE2 1 
ATOM   11393 C CZ  . TYR E 2 87  ? 116.851 149.476 106.568 1.00 20.80  ? 62  TYR E CZ  1 
ATOM   11394 O OH  . TYR E 2 87  ? 115.912 148.509 106.839 1.00 29.28  ? 62  TYR E OH  1 
ATOM   11395 N N   . PHE E 2 88  ? 123.189 152.901 105.120 1.00 11.14  ? 63  PHE E N   1 
ATOM   11396 C CA  . PHE E 2 88  ? 124.337 153.764 104.874 1.00 12.27  ? 63  PHE E CA  1 
ATOM   11397 C C   . PHE E 2 88  ? 124.294 154.183 103.414 1.00 13.76  ? 63  PHE E C   1 
ATOM   11398 O O   . PHE E 2 88  ? 124.448 153.348 102.519 1.00 17.04  ? 63  PHE E O   1 
ATOM   11399 C CB  . PHE E 2 88  ? 125.641 153.041 105.202 1.00 12.94  ? 63  PHE E CB  1 
ATOM   11400 C CG  . PHE E 2 88  ? 126.870 153.881 105.003 1.00 12.58  ? 63  PHE E CG  1 
ATOM   11401 C CD1 . PHE E 2 88  ? 127.102 154.996 105.786 1.00 13.91  ? 63  PHE E CD1 1 
ATOM   11402 C CD2 . PHE E 2 88  ? 127.792 153.552 104.026 1.00 13.06  ? 63  PHE E CD2 1 
ATOM   11403 C CE1 . PHE E 2 88  ? 128.230 155.766 105.598 1.00 14.14  ? 63  PHE E CE1 1 
ATOM   11404 C CE2 . PHE E 2 88  ? 128.922 154.319 103.835 1.00 15.45  ? 63  PHE E CE2 1 
ATOM   11405 C CZ  . PHE E 2 88  ? 129.139 155.426 104.622 1.00 15.55  ? 63  PHE E CZ  1 
ATOM   11406 N N   . GLN E 2 89  ? 124.095 155.475 103.180 1.00 14.52  ? 64  GLN E N   1 
ATOM   11407 C CA  . GLN E 2 89  ? 123.953 156.016 101.840 1.00 18.70  ? 64  GLN E CA  1 
ATOM   11408 C C   . GLN E 2 89  ? 125.142 156.904 101.509 1.00 19.54  ? 64  GLN E C   1 
ATOM   11409 O O   . GLN E 2 89  ? 125.625 157.656 102.360 1.00 23.25  ? 64  GLN E O   1 
ATOM   11410 C CB  . GLN E 2 89  ? 122.660 156.823 101.728 1.00 23.13  ? 64  GLN E CB  1 
ATOM   11411 C CG  . GLN E 2 89  ? 121.431 155.986 101.461 1.00 24.12  ? 64  GLN E CG  1 
ATOM   11412 C CD  . GLN E 2 89  ? 120.158 156.709 101.841 1.00 33.30  ? 64  GLN E CD  1 
ATOM   11413 O OE1 . GLN E 2 89  ? 120.061 157.929 101.709 1.00 34.48  ? 64  GLN E OE1 1 
ATOM   11414 N NE2 . GLN E 2 89  ? 119.184 155.964 102.346 1.00 32.31  ? 64  GLN E NE2 1 
ATOM   11415 N N   . GLN E 2 90  ? 125.613 156.806 100.270 1.00 19.15  ? 65  GLN E N   1 
ATOM   11416 C CA  . GLN E 2 90  ? 126.688 157.643 99.766  1.00 23.38  ? 65  GLN E CA  1 
ATOM   11417 C C   . GLN E 2 90  ? 126.255 158.288 98.461  1.00 24.56  ? 65  GLN E C   1 
ATOM   11418 O O   . GLN E 2 90  ? 125.676 157.625 97.595  1.00 28.96  ? 65  GLN E O   1 
ATOM   11419 C CB  . GLN E 2 90  ? 127.969 156.839 99.538  1.00 27.89  ? 65  GLN E CB  1 
ATOM   11420 C CG  . GLN E 2 90  ? 128.475 156.107 100.760 1.00 24.31  ? 65  GLN E CG  1 
ATOM   11421 C CD  . GLN E 2 90  ? 129.781 155.390 100.499 1.00 24.90  ? 65  GLN E CD  1 
ATOM   11422 O OE1 . GLN E 2 90  ? 130.852 155.995 100.534 1.00 25.55  ? 65  GLN E OE1 1 
ATOM   11423 N NE2 . GLN E 2 90  ? 129.700 154.094 100.228 1.00 25.19  ? 65  GLN E NE2 1 
ATOM   11424 N N   . TYR E 2 91  ? 126.531 159.579 98.323  1.00 24.44  ? 66  TYR E N   1 
ATOM   11425 C CA  . TYR E 2 91  ? 126.209 160.323 97.115  1.00 29.80  ? 66  TYR E CA  1 
ATOM   11426 C C   . TYR E 2 91  ? 127.479 160.931 96.544  1.00 31.81  ? 66  TYR E C   1 
ATOM   11427 O O   . TYR E 2 91  ? 128.260 161.546 97.275  1.00 35.81  ? 66  TYR E O   1 
ATOM   11428 C CB  . TYR E 2 91  ? 125.174 161.418 97.385  1.00 36.84  ? 66  TYR E CB  1 
ATOM   11429 C CG  . TYR E 2 91  ? 123.817 160.908 97.814  1.00 40.04  ? 66  TYR E CG  1 
ATOM   11430 C CD1 . TYR E 2 91  ? 123.591 160.466 99.108  1.00 40.18  ? 66  TYR E CD1 1 
ATOM   11431 C CD2 . TYR E 2 91  ? 122.753 160.892 96.921  1.00 38.75  ? 66  TYR E CD2 1 
ATOM   11432 C CE1 . TYR E 2 91  ? 122.348 160.007 99.496  1.00 36.20  ? 66  TYR E CE1 1 
ATOM   11433 C CE2 . TYR E 2 91  ? 121.507 160.437 97.302  1.00 42.09  ? 66  TYR E CE2 1 
ATOM   11434 C CZ  . TYR E 2 91  ? 121.310 159.998 98.592  1.00 38.15  ? 66  TYR E CZ  1 
ATOM   11435 O OH  . TYR E 2 91  ? 120.071 159.541 98.977  1.00 34.56  ? 66  TYR E OH  1 
ATOM   11436 N N   . TRP E 2 92  ? 127.681 160.748 95.243  1.00 31.16  ? 67  TRP E N   1 
ATOM   11437 C CA  . TRP E 2 92  ? 128.769 161.389 94.524  1.00 31.04  ? 67  TRP E CA  1 
ATOM   11438 C C   . TRP E 2 92  ? 128.371 161.493 93.062  1.00 35.16  ? 67  TRP E C   1 
ATOM   11439 O O   . TRP E 2 92  ? 127.461 160.801 92.599  1.00 39.65  ? 67  TRP E O   1 
ATOM   11440 C CB  . TRP E 2 92  ? 130.088 160.623 94.685  1.00 34.10  ? 67  TRP E CB  1 
ATOM   11441 C CG  . TRP E 2 92  ? 130.110 159.291 94.003  1.00 32.90  ? 67  TRP E CG  1 
ATOM   11442 C CD1 . TRP E 2 92  ? 130.542 159.025 92.738  1.00 34.71  ? 67  TRP E CD1 1 
ATOM   11443 C CD2 . TRP E 2 92  ? 129.696 158.037 94.557  1.00 32.09  ? 67  TRP E CD2 1 
ATOM   11444 N NE1 . TRP E 2 92  ? 130.414 157.685 92.466  1.00 33.27  ? 67  TRP E NE1 1 
ATOM   11445 C CE2 . TRP E 2 92  ? 129.898 157.056 93.568  1.00 34.13  ? 67  TRP E CE2 1 
ATOM   11446 C CE3 . TRP E 2 92  ? 129.169 157.649 95.791  1.00 28.80  ? 67  TRP E CE3 1 
ATOM   11447 C CZ2 . TRP E 2 92  ? 129.592 155.715 93.775  1.00 34.26  ? 67  TRP E CZ2 1 
ATOM   11448 C CZ3 . TRP E 2 92  ? 128.867 156.317 95.994  1.00 27.30  ? 67  TRP E CZ3 1 
ATOM   11449 C CH2 . TRP E 2 92  ? 129.078 155.367 94.992  1.00 29.48  ? 67  TRP E CH2 1 
ATOM   11450 N N   . ARG E 2 93  ? 129.063 162.360 92.333  1.00 37.70  ? 68  ARG E N   1 
ATOM   11451 C CA  . ARG E 2 93  ? 128.781 162.578 90.922  1.00 50.17  ? 68  ARG E CA  1 
ATOM   11452 C C   . ARG E 2 93  ? 129.859 161.918 90.075  1.00 50.91  ? 68  ARG E C   1 
ATOM   11453 O O   . ARG E 2 93  ? 131.051 162.183 90.261  1.00 46.22  ? 68  ARG E O   1 
ATOM   11454 C CB  . ARG E 2 93  ? 128.691 164.070 90.598  1.00 54.20  ? 68  ARG E CB  1 
ATOM   11455 C CG  . ARG E 2 93  ? 128.105 164.352 89.224  1.00 54.25  ? 68  ARG E CG  1 
ATOM   11456 C CD  . ARG E 2 93  ? 127.752 165.817 89.049  1.00 52.37  ? 68  ARG E CD  1 
ATOM   11457 N NE  . ARG E 2 93  ? 127.057 166.053 87.789  1.00 68.36  ? 68  ARG E NE  1 
ATOM   11458 C CZ  . ARG E 2 93  ? 127.659 166.346 86.645  1.00 70.88  ? 68  ARG E CZ  1 
ATOM   11459 N NH1 . ARG E 2 93  ? 128.976 166.445 86.562  1.00 62.13  ? 68  ARG E NH1 1 
ATOM   11460 N NH2 . ARG E 2 93  ? 126.922 166.541 85.555  1.00 78.71  ? 68  ARG E NH2 1 
ATOM   11461 N N   . ASP E 2 94  ? 129.434 161.058 89.153  1.00 53.05  ? 69  ASP E N   1 
ATOM   11462 C CA  . ASP E 2 94  ? 130.327 160.373 88.225  1.00 56.07  ? 69  ASP E CA  1 
ATOM   11463 C C   . ASP E 2 94  ? 129.852 160.695 86.815  1.00 59.35  ? 69  ASP E C   1 
ATOM   11464 O O   . ASP E 2 94  ? 128.814 160.189 86.376  1.00 60.19  ? 69  ASP E O   1 
ATOM   11465 C CB  . ASP E 2 94  ? 130.342 158.867 88.480  1.00 57.45  ? 69  ASP E CB  1 
ATOM   11466 C CG  . ASP E 2 94  ? 131.459 158.160 87.735  1.00 56.81  ? 69  ASP E CG  1 
ATOM   11467 O OD1 . ASP E 2 94  ? 132.142 158.809 86.916  1.00 55.69  ? 69  ASP E OD1 1 
ATOM   11468 O OD2 . ASP E 2 94  ? 131.661 156.952 87.976  1.00 57.39  ? 69  ASP E OD2 1 
ATOM   11469 N N   . LYS E 2 95  ? 130.611 161.537 86.111  1.00 62.12  ? 70  LYS E N   1 
ATOM   11470 C CA  . LYS E 2 95  ? 130.213 161.955 84.771  1.00 67.90  ? 70  LYS E CA  1 
ATOM   11471 C C   . LYS E 2 95  ? 130.160 160.778 83.806  1.00 68.38  ? 70  LYS E C   1 
ATOM   11472 O O   . LYS E 2 95  ? 129.364 160.785 82.860  1.00 67.14  ? 70  LYS E O   1 
ATOM   11473 C CB  . LYS E 2 95  ? 131.176 163.026 84.261  1.00 59.92  ? 70  LYS E CB  1 
ATOM   11474 C CG  . LYS E 2 95  ? 131.219 164.270 85.133  1.00 60.48  ? 70  LYS E CG  1 
ATOM   11475 C CD  . LYS E 2 95  ? 132.352 165.195 84.726  1.00 61.64  ? 70  LYS E CD  1 
ATOM   11476 C CE  . LYS E 2 95  ? 132.442 166.394 85.656  1.00 58.78  ? 70  LYS E CE  1 
ATOM   11477 N NZ  . LYS E 2 95  ? 133.565 167.301 85.289  1.00 54.34  ? 70  LYS E NZ  1 
ATOM   11478 N N   . ARG E 2 96  ? 130.999 159.763 84.026  1.00 67.03  ? 71  ARG E N   1 
ATOM   11479 C CA  . ARG E 2 96  ? 130.996 158.572 83.185  1.00 66.90  ? 71  ARG E CA  1 
ATOM   11480 C C   . ARG E 2 96  ? 129.667 157.828 83.226  1.00 68.85  ? 71  ARG E C   1 
ATOM   11481 O O   . ARG E 2 96  ? 129.388 157.033 82.321  1.00 73.25  ? 71  ARG E O   1 
ATOM   11482 C CB  . ARG E 2 96  ? 132.116 157.626 83.621  1.00 67.68  ? 71  ARG E CB  1 
ATOM   11483 C CG  . ARG E 2 96  ? 133.516 158.190 83.482  1.00 62.53  ? 71  ARG E CG  1 
ATOM   11484 C CD  . ARG E 2 96  ? 134.538 157.221 84.054  1.00 59.53  ? 71  ARG E CD  1 
ATOM   11485 N NE  . ARG E 2 96  ? 134.471 157.174 85.510  1.00 59.28  ? 71  ARG E NE  1 
ATOM   11486 C CZ  . ARG E 2 96  ? 135.165 156.336 86.268  1.00 58.76  ? 71  ARG E CZ  1 
ATOM   11487 N NH1 . ARG E 2 96  ? 135.983 155.441 85.739  1.00 60.86  ? 71  ARG E NH1 1 
ATOM   11488 N NH2 . ARG E 2 96  ? 135.028 156.392 87.589  1.00 52.57  ? 71  ARG E NH2 1 
ATOM   11489 N N   . LEU E 2 97  ? 128.845 158.061 84.251  1.00 66.63  ? 72  LEU E N   1 
ATOM   11490 C CA  . LEU E 2 97  ? 127.568 157.376 84.413  1.00 68.41  ? 72  LEU E CA  1 
ATOM   11491 C C   . LEU E 2 97  ? 126.366 158.255 84.083  1.00 69.31  ? 72  LEU E C   1 
ATOM   11492 O O   . LEU E 2 97  ? 125.238 157.911 84.449  1.00 69.18  ? 72  LEU E O   1 
ATOM   11493 C CB  . LEU E 2 97  ? 127.443 156.826 85.834  1.00 65.11  ? 72  LEU E CB  1 
ATOM   11494 C CG  . LEU E 2 97  ? 128.533 155.847 86.268  1.00 64.21  ? 72  LEU E CG  1 
ATOM   11495 C CD1 . LEU E 2 97  ? 128.332 155.421 87.714  1.00 60.60  ? 72  LEU E CD1 1 
ATOM   11496 C CD2 . LEU E 2 97  ? 128.546 154.639 85.348  1.00 64.04  ? 72  LEU E CD2 1 
ATOM   11497 N N   . ALA E 2 98  ? 126.573 159.384 83.413  1.00 66.81  ? 73  ALA E N   1 
ATOM   11498 C CA  . ALA E 2 98  ? 125.439 160.195 82.995  1.00 67.81  ? 73  ALA E CA  1 
ATOM   11499 C C   . ALA E 2 98  ? 124.709 159.522 81.837  1.00 67.84  ? 73  ALA E C   1 
ATOM   11500 O O   . ALA E 2 98  ? 125.330 158.927 80.952  1.00 63.83  ? 73  ALA E O   1 
ATOM   11501 C CB  . ALA E 2 98  ? 125.903 161.592 82.587  1.00 70.51  ? 73  ALA E CB  1 
ATOM   11502 N N   . TYR E 2 99  ? 123.381 159.623 81.845  1.00 72.05  ? 74  TYR E N   1 
ATOM   11503 C CA  . TYR E 2 99  ? 122.557 159.049 80.792  1.00 72.71  ? 74  TYR E CA  1 
ATOM   11504 C C   . TYR E 2 99  ? 121.394 159.977 80.475  1.00 73.97  ? 74  TYR E C   1 
ATOM   11505 O O   . TYR E 2 99  ? 120.955 160.761 81.320  1.00 71.55  ? 74  TYR E O   1 
ATOM   11506 C CB  . TYR E 2 99  ? 122.051 157.651 81.183  1.00 74.87  ? 74  TYR E CB  1 
ATOM   11507 C CG  . TYR E 2 99  ? 121.163 157.616 82.408  1.00 77.18  ? 74  TYR E CG  1 
ATOM   11508 C CD1 . TYR E 2 99  ? 119.789 157.788 82.307  1.00 79.34  ? 74  TYR E CD1 1 
ATOM   11509 C CD2 . TYR E 2 99  ? 121.702 157.395 83.668  1.00 71.70  ? 74  TYR E CD2 1 
ATOM   11510 C CE1 . TYR E 2 99  ? 118.979 157.749 83.427  1.00 76.09  ? 74  TYR E CE1 1 
ATOM   11511 C CE2 . TYR E 2 99  ? 120.902 157.354 84.793  1.00 63.14  ? 74  TYR E CE2 1 
ATOM   11512 C CZ  . TYR E 2 99  ? 119.542 157.531 84.667  1.00 69.05  ? 74  TYR E CZ  1 
ATOM   11513 O OH  . TYR E 2 99  ? 118.744 157.492 85.787  1.00 71.02  ? 74  TYR E OH  1 
ATOM   11514 N N   . SER E 2 100 ? 120.896 159.872 79.244  1.00 80.31  ? 75  SER E N   1 
ATOM   11515 C CA  . SER E 2 100 ? 119.815 160.717 78.761  1.00 87.04  ? 75  SER E CA  1 
ATOM   11516 C C   . SER E 2 100 ? 118.809 159.872 77.992  1.00 91.60  ? 75  SER E C   1 
ATOM   11517 O O   . SER E 2 100 ? 119.119 158.777 77.516  1.00 87.88  ? 75  SER E O   1 
ATOM   11518 C CB  . SER E 2 100 ? 120.338 161.850 77.867  1.00 90.89  ? 75  SER E CB  1 
ATOM   11519 O OG  . SER E 2 100 ? 121.027 161.333 76.742  1.00 94.90  ? 75  SER E OG  1 
ATOM   11520 N N   . GLY E 2 101 ? 117.590 160.400 77.874  1.00 90.90  ? 76  GLY E N   1 
ATOM   11521 C CA  . GLY E 2 101 ? 116.511 159.708 77.206  1.00 93.41  ? 76  GLY E CA  1 
ATOM   11522 C C   . GLY E 2 101 ? 115.671 158.806 78.082  1.00 94.84  ? 76  GLY E C   1 
ATOM   11523 O O   . GLY E 2 101 ? 114.656 158.280 77.607  1.00 93.86  ? 76  GLY E O   1 
ATOM   11524 N N   . ILE E 2 102 ? 116.052 158.604 79.336  1.00 96.12  ? 77  ILE E N   1 
ATOM   11525 C CA  . ILE E 2 102 ? 115.295 157.790 80.275  1.00 97.23  ? 77  ILE E CA  1 
ATOM   11526 C C   . ILE E 2 102 ? 114.819 158.686 81.411  1.00 96.01  ? 77  ILE E C   1 
ATOM   11527 O O   . ILE E 2 102 ? 115.583 159.012 82.321  1.00 93.17  ? 77  ILE E O   1 
ATOM   11528 C CB  . ILE E 2 102 ? 116.135 156.617 80.808  1.00 96.27  ? 77  ILE E CB  1 
ATOM   11529 C CG1 . ILE E 2 102 ? 116.733 155.822 79.645  1.00 96.08  ? 77  ILE E CG1 1 
ATOM   11530 C CG2 . ILE E 2 102 ? 115.292 155.722 81.703  1.00 90.97  ? 77  ILE E CG2 1 
ATOM   11531 C CD1 . ILE E 2 102 ? 117.673 154.721 80.075  1.00 90.50  ? 77  ILE E CD1 1 
ATOM   11532 N N   . PRO E 2 103 ? 113.545 159.105 81.395  1.00 100.47 ? 78  PRO E N   1 
ATOM   11533 C CA  . PRO E 2 103 ? 113.010 160.003 82.427  1.00 102.86 ? 78  PRO E CA  1 
ATOM   11534 C C   . PRO E 2 103 ? 112.688 159.289 83.739  1.00 99.25  ? 78  PRO E C   1 
ATOM   11535 O O   . PRO E 2 103 ? 111.615 159.465 84.317  1.00 98.38  ? 78  PRO E O   1 
ATOM   11536 C CB  . PRO E 2 103 ? 111.750 160.564 81.762  1.00 102.57 ? 78  PRO E CB  1 
ATOM   11537 C CG  . PRO E 2 103 ? 111.281 159.445 80.897  1.00 103.06 ? 78  PRO E CG  1 
ATOM   11538 C CD  . PRO E 2 103 ? 112.529 158.762 80.384  1.00 102.90 ? 78  PRO E CD  1 
ATOM   11539 N N   . LEU E 2 104 ? 113.633 158.482 84.216  1.00 95.84  ? 79  LEU E N   1 
ATOM   11540 C CA  . LEU E 2 104 ? 113.451 157.717 85.439  1.00 89.49  ? 79  LEU E CA  1 
ATOM   11541 C C   . LEU E 2 104 ? 114.800 157.547 86.118  1.00 82.88  ? 79  LEU E C   1 
ATOM   11542 O O   . LEU E 2 104 ? 115.846 157.558 85.464  1.00 79.95  ? 79  LEU E O   1 
ATOM   11543 C CB  . LEU E 2 104 ? 112.838 156.337 85.162  1.00 88.49  ? 79  LEU E CB  1 
ATOM   11544 C CG  . LEU E 2 104 ? 111.386 156.247 84.689  1.00 89.70  ? 79  LEU E CG  1 
ATOM   11545 C CD1 . LEU E 2 104 ? 111.047 154.817 84.307  1.00 86.57  ? 79  LEU E CD1 1 
ATOM   11546 C CD2 . LEU E 2 104 ? 110.439 156.754 85.765  1.00 91.37  ? 79  LEU E CD2 1 
ATOM   11547 N N   . ASN E 2 105 ? 114.766 157.390 87.438  1.00 76.74  ? 80  ASN E N   1 
ATOM   11548 C CA  . ASN E 2 105 ? 115.950 156.980 88.176  1.00 68.46  ? 80  ASN E CA  1 
ATOM   11549 C C   . ASN E 2 105 ? 116.072 155.464 88.112  1.00 63.10  ? 80  ASN E C   1 
ATOM   11550 O O   . ASN E 2 105 ? 115.128 154.745 88.451  1.00 66.45  ? 80  ASN E O   1 
ATOM   11551 C CB  . ASN E 2 105 ? 115.859 157.451 89.626  1.00 62.59  ? 80  ASN E CB  1 
ATOM   11552 C CG  . ASN E 2 105 ? 115.688 158.950 89.736  1.00 68.11  ? 80  ASN E CG  1 
ATOM   11553 O OD1 . ASN E 2 105 ? 116.135 159.703 88.871  1.00 68.24  ? 80  ASN E OD1 1 
ATOM   11554 N ND2 . ASN E 2 105 ? 115.030 159.393 90.799  1.00 71.94  ? 80  ASN E ND2 1 
ATOM   11555 N N   . LEU E 2 106 ? 117.232 154.975 87.681  1.00 54.79  ? 81  LEU E N   1 
ATOM   11556 C CA  . LEU E 2 106 ? 117.405 153.545 87.434  1.00 50.27  ? 81  LEU E CA  1 
ATOM   11557 C C   . LEU E 2 106 ? 117.880 152.882 88.720  1.00 42.77  ? 81  LEU E C   1 
ATOM   11558 O O   . LEU E 2 106 ? 119.052 152.978 89.086  1.00 44.86  ? 81  LEU E O   1 
ATOM   11559 C CB  . LEU E 2 106 ? 118.390 153.308 86.296  1.00 52.99  ? 81  LEU E CB  1 
ATOM   11560 C CG  . LEU E 2 106 ? 117.995 153.823 84.913  1.00 69.00  ? 81  LEU E CG  1 
ATOM   11561 C CD1 . LEU E 2 106 ? 119.093 153.526 83.905  1.00 70.44  ? 81  LEU E CD1 1 
ATOM   11562 C CD2 . LEU E 2 106 ? 116.677 153.206 84.471  1.00 66.54  ? 81  LEU E CD2 1 
ATOM   11563 N N   . THR E 2 107 ? 116.966 152.204 89.407  1.00 39.89  ? 82  THR E N   1 
ATOM   11564 C CA  . THR E 2 107 ? 117.344 151.284 90.471  1.00 40.28  ? 82  THR E CA  1 
ATOM   11565 C C   . THR E 2 107 ? 117.761 149.956 89.852  1.00 42.12  ? 82  THR E C   1 
ATOM   11566 O O   . THR E 2 107 ? 116.968 149.320 89.149  1.00 43.12  ? 82  THR E O   1 
ATOM   11567 C CB  . THR E 2 107 ? 116.190 151.082 91.448  1.00 47.08  ? 82  THR E CB  1 
ATOM   11568 O OG1 . THR E 2 107 ? 115.772 152.350 91.967  1.00 51.36  ? 82  THR E OG1 1 
ATOM   11569 C CG2 . THR E 2 107 ? 116.627 150.190 92.594  1.00 42.54  ? 82  THR E CG2 1 
ATOM   11570 N N   . LEU E 2 108 ? 118.994 149.534 90.108  1.00 42.15  ? 83  LEU E N   1 
ATOM   11571 C CA  . LEU E 2 108 ? 119.546 148.364 89.447  1.00 43.01  ? 83  LEU E CA  1 
ATOM   11572 C C   . LEU E 2 108 ? 119.807 147.249 90.451  1.00 45.59  ? 83  LEU E C   1 
ATOM   11573 O O   . LEU E 2 108 ? 119.926 147.479 91.658  1.00 44.36  ? 83  LEU E O   1 
ATOM   11574 C CB  . LEU E 2 108 ? 120.843 148.719 88.711  1.00 35.91  ? 83  LEU E CB  1 
ATOM   11575 C CG  . LEU E 2 108 ? 120.718 149.828 87.667  1.00 37.22  ? 83  LEU E CG  1 
ATOM   11576 C CD1 . LEU E 2 108 ? 122.072 150.151 87.059  1.00 32.87  ? 83  LEU E CD1 1 
ATOM   11577 C CD2 . LEU E 2 108 ? 119.719 149.439 86.590  1.00 39.29  ? 83  LEU E CD2 1 
ATOM   11578 N N   . ASP E 2 109 ? 119.884 146.028 89.924  1.00 43.81  ? 84  ASP E N   1 
ATOM   11579 C CA  . ASP E 2 109 ? 120.258 144.864 90.716  1.00 44.56  ? 84  ASP E CA  1 
ATOM   11580 C C   . ASP E 2 109 ? 121.592 145.113 91.407  1.00 46.23  ? 84  ASP E C   1 
ATOM   11581 O O   . ASP E 2 109 ? 122.537 145.612 90.792  1.00 51.49  ? 84  ASP E O   1 
ATOM   11582 C CB  . ASP E 2 109 ? 120.335 143.625 89.820  1.00 48.87  ? 84  ASP E CB  1 
ATOM   11583 C CG  . ASP E 2 109 ? 120.688 142.360 90.587  1.00 47.49  ? 84  ASP E CG  1 
ATOM   11584 O OD1 . ASP E 2 109 ? 120.770 142.404 91.832  1.00 41.76  ? 84  ASP E OD1 1 
ATOM   11585 O OD2 . ASP E 2 109 ? 120.879 141.312 89.937  1.00 51.51  ? 84  ASP E OD2 1 
ATOM   11586 N N   . ASN E 2 110 ? 121.662 144.769 92.696  1.00 39.58  ? 85  ASN E N   1 
ATOM   11587 C CA  . ASN E 2 110 ? 122.832 145.110 93.499  1.00 39.08  ? 85  ASN E CA  1 
ATOM   11588 C C   . ASN E 2 110 ? 124.121 144.516 92.946  1.00 40.63  ? 85  ASN E C   1 
ATOM   11589 O O   . ASN E 2 110 ? 125.205 145.014 93.264  1.00 40.27  ? 85  ASN E O   1 
ATOM   11590 C CB  . ASN E 2 110 ? 122.637 144.634 94.936  1.00 33.74  ? 85  ASN E CB  1 
ATOM   11591 C CG  . ASN E 2 110 ? 122.698 143.126 95.061  1.00 35.57  ? 85  ASN E CG  1 
ATOM   11592 O OD1 . ASN E 2 110 ? 123.752 142.559 95.349  1.00 30.31  ? 85  ASN E OD1 1 
ATOM   11593 N ND2 . ASN E 2 110 ? 121.567 142.467 94.841  1.00 42.85  ? 85  ASN E ND2 1 
ATOM   11594 N N   . ARG E 2 111 ? 124.030 143.468 92.126  1.00 45.66  ? 86  ARG E N   1 
ATOM   11595 C CA  . ARG E 2 111 ? 125.214 142.856 91.539  1.00 46.00  ? 86  ARG E CA  1 
ATOM   11596 C C   . ARG E 2 111 ? 125.919 143.765 90.540  1.00 45.64  ? 86  ARG E C   1 
ATOM   11597 O O   . ARG E 2 111 ? 127.040 143.449 90.130  1.00 48.26  ? 86  ARG E O   1 
ATOM   11598 C CB  . ARG E 2 111 ? 124.825 141.537 90.871  1.00 47.69  ? 86  ARG E CB  1 
ATOM   11599 C CG  . ARG E 2 111 ? 124.519 140.426 91.863  1.00 49.23  ? 86  ARG E CG  1 
ATOM   11600 C CD  . ARG E 2 111 ? 124.238 139.110 91.164  1.00 56.96  ? 86  ARG E CD  1 
ATOM   11601 N NE  . ARG E 2 111 ? 122.966 139.155 90.453  1.00 64.08  ? 86  ARG E NE  1 
ATOM   11602 C CZ  . ARG E 2 111 ? 122.386 138.109 89.882  1.00 70.95  ? 86  ARG E CZ  1 
ATOM   11603 N NH1 . ARG E 2 111 ? 122.940 136.909 89.914  1.00 76.07  ? 86  ARG E NH1 1 
ATOM   11604 N NH2 . ARG E 2 111 ? 121.214 138.269 89.274  1.00 67.48  ? 86  ARG E NH2 1 
ATOM   11605 N N   . VAL E 2 112 ? 125.296 144.874 90.137  1.00 38.84  ? 87  VAL E N   1 
ATOM   11606 C CA  . VAL E 2 112 ? 125.975 145.827 89.268  1.00 39.59  ? 87  VAL E CA  1 
ATOM   11607 C C   . VAL E 2 112 ? 127.010 146.650 90.025  1.00 44.41  ? 87  VAL E C   1 
ATOM   11608 O O   . VAL E 2 112 ? 127.885 147.258 89.396  1.00 51.56  ? 87  VAL E O   1 
ATOM   11609 C CB  . VAL E 2 112 ? 124.960 146.759 88.582  1.00 36.81  ? 87  VAL E CB  1 
ATOM   11610 C CG1 . VAL E 2 112 ? 124.443 147.801 89.556  1.00 40.84  ? 87  VAL E CG1 1 
ATOM   11611 C CG2 . VAL E 2 112 ? 125.565 147.418 87.348  1.00 40.77  ? 87  VAL E CG2 1 
ATOM   11612 N N   . ALA E 2 113 ? 126.942 146.683 91.360  1.00 39.40  ? 88  ALA E N   1 
ATOM   11613 C CA  . ALA E 2 113 ? 127.915 147.454 92.129  1.00 37.34  ? 88  ALA E CA  1 
ATOM   11614 C C   . ALA E 2 113 ? 129.338 146.955 91.913  1.00 44.44  ? 88  ALA E C   1 
ATOM   11615 O O   . ALA E 2 113 ? 130.291 147.730 92.048  1.00 47.84  ? 88  ALA E O   1 
ATOM   11616 C CB  . ALA E 2 113 ? 127.562 147.414 93.614  1.00 32.00  ? 88  ALA E CB  1 
ATOM   11617 N N   . ASP E 2 114 ? 129.505 145.673 91.585  1.00 47.55  ? 89  ASP E N   1 
ATOM   11618 C CA  . ASP E 2 114 ? 130.835 145.147 91.310  1.00 49.54  ? 89  ASP E CA  1 
ATOM   11619 C C   . ASP E 2 114 ? 131.421 145.696 90.017  1.00 50.17  ? 89  ASP E C   1 
ATOM   11620 O O   . ASP E 2 114 ? 132.617 145.512 89.771  1.00 56.20  ? 89  ASP E O   1 
ATOM   11621 C CB  . ASP E 2 114 ? 130.795 143.620 91.254  1.00 49.12  ? 89  ASP E CB  1 
ATOM   11622 C CG  . ASP E 2 114 ? 130.248 143.007 92.527  1.00 50.90  ? 89  ASP E CG  1 
ATOM   11623 O OD1 . ASP E 2 114 ? 130.434 143.611 93.603  1.00 53.83  ? 89  ASP E OD1 1 
ATOM   11624 O OD2 . ASP E 2 114 ? 129.633 141.922 92.452  1.00 46.99  ? 89  ASP E OD2 1 
ATOM   11625 N N   . GLN E 2 115 ? 130.610 146.362 89.193  1.00 48.11  ? 90  GLN E N   1 
ATOM   11626 C CA  . GLN E 2 115 ? 131.037 146.884 87.902  1.00 49.91  ? 90  GLN E CA  1 
ATOM   11627 C C   . GLN E 2 115 ? 131.129 148.405 87.902  1.00 48.50  ? 90  GLN E C   1 
ATOM   11628 O O   . GLN E 2 115 ? 131.120 149.025 86.835  1.00 55.19  ? 90  GLN E O   1 
ATOM   11629 C CB  . GLN E 2 115 ? 130.085 146.410 86.803  1.00 54.74  ? 90  GLN E CB  1 
ATOM   11630 C CG  . GLN E 2 115 ? 129.801 144.918 86.837  1.00 55.34  ? 90  GLN E CG  1 
ATOM   11631 C CD  . GLN E 2 115 ? 128.824 144.484 85.763  1.00 62.94  ? 90  GLN E CD  1 
ATOM   11632 O OE1 . GLN E 2 115 ? 129.065 144.680 84.571  1.00 74.14  ? 90  GLN E OE1 1 
ATOM   11633 N NE2 . GLN E 2 115 ? 127.712 143.890 86.181  1.00 53.38  ? 90  GLN E NE2 1 
ATOM   11634 N N   . LEU E 2 116 ? 131.217 149.016 89.079  1.00 49.51  ? 91  LEU E N   1 
ATOM   11635 C CA  . LEU E 2 116 ? 131.269 150.461 89.217  1.00 53.87  ? 91  LEU E CA  1 
ATOM   11636 C C   . LEU E 2 116 ? 132.362 150.830 90.207  1.00 52.56  ? 91  LEU E C   1 
ATOM   11637 O O   . LEU E 2 116 ? 132.778 150.018 91.037  1.00 53.07  ? 91  LEU E O   1 
ATOM   11638 C CB  . LEU E 2 116 ? 129.927 151.033 89.696  1.00 49.73  ? 91  LEU E CB  1 
ATOM   11639 C CG  . LEU E 2 116 ? 128.715 150.879 88.780  1.00 43.81  ? 91  LEU E CG  1 
ATOM   11640 C CD1 . LEU E 2 116 ? 127.484 151.480 89.434  1.00 35.38  ? 91  LEU E CD1 1 
ATOM   11641 C CD2 . LEU E 2 116 ? 128.980 151.539 87.447  1.00 48.63  ? 91  LEU E CD2 1 
ATOM   11642 N N   . TRP E 2 117 ? 132.822 152.074 90.119  1.00 46.03  ? 92  TRP E N   1 
ATOM   11643 C CA  . TRP E 2 117 ? 133.707 152.605 91.142  1.00 43.54  ? 92  TRP E CA  1 
ATOM   11644 C C   . TRP E 2 117 ? 132.883 153.054 92.339  1.00 42.32  ? 92  TRP E C   1 
ATOM   11645 O O   . TRP E 2 117 ? 131.914 153.805 92.192  1.00 42.64  ? 92  TRP E O   1 
ATOM   11646 C CB  . TRP E 2 117 ? 134.528 153.769 90.590  1.00 48.81  ? 92  TRP E CB  1 
ATOM   11647 C CG  . TRP E 2 117 ? 135.446 154.395 91.597  1.00 47.59  ? 92  TRP E CG  1 
ATOM   11648 C CD1 . TRP E 2 117 ? 136.756 154.083 91.813  1.00 49.23  ? 92  TRP E CD1 1 
ATOM   11649 C CD2 . TRP E 2 117 ? 135.132 155.456 92.507  1.00 46.42  ? 92  TRP E CD2 1 
ATOM   11650 N NE1 . TRP E 2 117 ? 137.273 154.872 92.810  1.00 49.15  ? 92  TRP E NE1 1 
ATOM   11651 C CE2 . TRP E 2 117 ? 136.296 155.725 93.252  1.00 45.21  ? 92  TRP E CE2 1 
ATOM   11652 C CE3 . TRP E 2 117 ? 133.978 156.200 92.769  1.00 45.51  ? 92  TRP E CE3 1 
ATOM   11653 C CZ2 . TRP E 2 117 ? 136.340 156.705 94.241  1.00 41.87  ? 92  TRP E CZ2 1 
ATOM   11654 C CZ3 . TRP E 2 117 ? 134.024 157.173 93.751  1.00 39.16  ? 92  TRP E CZ3 1 
ATOM   11655 C CH2 . TRP E 2 117 ? 135.196 157.416 94.474  1.00 38.49  ? 92  TRP E CH2 1 
ATOM   11656 N N   . VAL E 2 118 ? 133.270 152.594 93.522  1.00 42.53  ? 93  VAL E N   1 
ATOM   11657 C CA  . VAL E 2 118 ? 132.621 153.013 94.758  1.00 38.45  ? 93  VAL E CA  1 
ATOM   11658 C C   . VAL E 2 118 ? 133.700 153.503 95.715  1.00 37.55  ? 93  VAL E C   1 
ATOM   11659 O O   . VAL E 2 118 ? 134.849 153.043 95.635  1.00 39.42  ? 93  VAL E O   1 
ATOM   11660 C CB  . VAL E 2 118 ? 131.795 151.873 95.374  1.00 34.74  ? 93  VAL E CB  1 
ATOM   11661 C CG1 . VAL E 2 118 ? 130.620 151.528 94.477  1.00 33.91  ? 93  VAL E CG1 1 
ATOM   11662 C CG2 . VAL E 2 118 ? 132.668 150.651 95.608  1.00 32.56  ? 93  VAL E CG2 1 
ATOM   11663 N N   . PRO E 2 119 ? 133.391 154.439 96.608  1.00 35.62  ? 94  PRO E N   1 
ATOM   11664 C CA  . PRO E 2 119 ? 134.402 154.914 97.556  1.00 35.20  ? 94  PRO E CA  1 
ATOM   11665 C C   . PRO E 2 119 ? 134.929 153.775 98.413  1.00 33.15  ? 94  PRO E C   1 
ATOM   11666 O O   . PRO E 2 119 ? 134.203 152.842 98.764  1.00 29.72  ? 94  PRO E O   1 
ATOM   11667 C CB  . PRO E 2 119 ? 133.645 155.947 98.398  1.00 37.09  ? 94  PRO E CB  1 
ATOM   11668 C CG  . PRO E 2 119 ? 132.519 156.385 97.533  1.00 35.50  ? 94  PRO E CG  1 
ATOM   11669 C CD  . PRO E 2 119 ? 132.128 155.186 96.727  1.00 35.04  ? 94  PRO E CD  1 
ATOM   11670 N N   . ASP E 2 120 ? 136.213 153.863 98.753  1.00 33.58  ? 95  ASP E N   1 
ATOM   11671 C CA  . ASP E 2 120 ? 136.825 152.879 99.635  1.00 30.87  ? 95  ASP E CA  1 
ATOM   11672 C C   . ASP E 2 120 ? 136.543 153.264 101.080 1.00 29.68  ? 95  ASP E C   1 
ATOM   11673 O O   . ASP E 2 120 ? 137.454 153.365 101.907 1.00 29.05  ? 95  ASP E O   1 
ATOM   11674 C CB  . ASP E 2 120 ? 138.328 152.773 99.366  1.00 33.83  ? 95  ASP E CB  1 
ATOM   11675 C CG  . ASP E 2 120 ? 139.062 154.074 99.626  1.00 37.27  ? 95  ASP E CG  1 
ATOM   11676 O OD1 . ASP E 2 120 ? 138.410 155.139 99.614  1.00 35.11  ? 95  ASP E OD1 1 
ATOM   11677 O OD2 . ASP E 2 120 ? 140.291 154.031 99.848  1.00 37.66  ? 95  ASP E OD2 1 
ATOM   11678 N N   . THR E 2 121 ? 135.265 153.462 101.384 1.00 28.07  ? 96  THR E N   1 
ATOM   11679 C CA  . THR E 2 121 ? 134.853 153.875 102.713 1.00 20.84  ? 96  THR E CA  1 
ATOM   11680 C C   . THR E 2 121 ? 134.948 152.710 103.688 1.00 21.16  ? 96  THR E C   1 
ATOM   11681 O O   . THR E 2 121 ? 134.629 151.567 103.351 1.00 29.32  ? 96  THR E O   1 
ATOM   11682 C CB  . THR E 2 121 ? 133.421 154.405 102.669 1.00 19.96  ? 96  THR E CB  1 
ATOM   11683 O OG1 . THR E 2 121 ? 133.321 155.434 101.677 1.00 23.63  ? 96  THR E OG1 1 
ATOM   11684 C CG2 . THR E 2 121 ? 133.012 154.961 104.006 1.00 18.80  ? 96  THR E CG2 1 
ATOM   11685 N N   . TYR E 2 122 ? 135.388 153.009 104.905 1.00 16.77  ? 97  TYR E N   1 
ATOM   11686 C CA  . TYR E 2 122 ? 135.450 152.013 105.959 1.00 17.25  ? 97  TYR E CA  1 
ATOM   11687 C C   . TYR E 2 122 ? 135.221 152.718 107.284 1.00 15.43  ? 97  TYR E C   1 
ATOM   11688 O O   . TYR E 2 122 ? 135.256 153.947 107.373 1.00 18.76  ? 97  TYR E O   1 
ATOM   11689 C CB  . TYR E 2 122 ? 136.784 151.257 105.964 1.00 22.22  ? 97  TYR E CB  1 
ATOM   11690 C CG  . TYR E 2 122 ? 137.944 152.023 106.561 1.00 23.18  ? 97  TYR E CG  1 
ATOM   11691 C CD1 . TYR E 2 122 ? 138.525 153.084 105.889 1.00 23.41  ? 97  TYR E CD1 1 
ATOM   11692 C CD2 . TYR E 2 122 ? 138.465 151.670 107.798 1.00 21.89  ? 97  TYR E CD2 1 
ATOM   11693 C CE1 . TYR E 2 122 ? 139.585 153.780 106.436 1.00 21.88  ? 97  TYR E CE1 1 
ATOM   11694 C CE2 . TYR E 2 122 ? 139.524 152.358 108.351 1.00 19.83  ? 97  TYR E CE2 1 
ATOM   11695 C CZ  . TYR E 2 122 ? 140.081 153.411 107.665 1.00 21.07  ? 97  TYR E CZ  1 
ATOM   11696 O OH  . TYR E 2 122 ? 141.136 154.100 108.212 1.00 25.26  ? 97  TYR E OH  1 
ATOM   11697 N N   . PHE E 2 123 ? 134.972 151.926 108.312 1.00 13.87  ? 98  PHE E N   1 
ATOM   11698 C CA  . PHE E 2 123 ? 134.676 152.437 109.642 1.00 13.32  ? 98  PHE E CA  1 
ATOM   11699 C C   . PHE E 2 123 ? 135.936 152.278 110.481 1.00 14.03  ? 98  PHE E C   1 
ATOM   11700 O O   . PHE E 2 123 ? 136.339 151.158 110.806 1.00 19.20  ? 98  PHE E O   1 
ATOM   11701 C CB  . PHE E 2 123 ? 133.477 151.709 110.241 1.00 17.71  ? 98  PHE E CB  1 
ATOM   11702 C CG  . PHE E 2 123 ? 132.266 151.744 109.356 1.00 19.19  ? 98  PHE E CG  1 
ATOM   11703 C CD1 . PHE E 2 123 ? 131.567 152.922 109.166 1.00 17.25  ? 98  PHE E CD1 1 
ATOM   11704 C CD2 . PHE E 2 123 ? 131.847 150.610 108.686 1.00 17.16  ? 98  PHE E CD2 1 
ATOM   11705 C CE1 . PHE E 2 123 ? 130.465 152.964 108.343 1.00 15.49  ? 98  PHE E CE1 1 
ATOM   11706 C CE2 . PHE E 2 123 ? 130.745 150.648 107.861 1.00 15.42  ? 98  PHE E CE2 1 
ATOM   11707 C CZ  . PHE E 2 123 ? 130.055 151.826 107.688 1.00 18.76  ? 98  PHE E CZ  1 
ATOM   11708 N N   . LEU E 2 124 ? 136.556 153.409 110.822 1.00 14.99  ? 99  LEU E N   1 
ATOM   11709 C CA  . LEU E 2 124 ? 137.907 153.396 111.371 1.00 16.61  ? 99  LEU E CA  1 
ATOM   11710 C C   . LEU E 2 124 ? 137.971 152.678 112.711 1.00 17.82  ? 99  LEU E C   1 
ATOM   11711 O O   . LEU E 2 124 ? 139.013 152.113 113.060 1.00 22.88  ? 99  LEU E O   1 
ATOM   11712 C CB  . LEU E 2 124 ? 138.411 154.833 111.512 1.00 17.59  ? 99  LEU E CB  1 
ATOM   11713 C CG  . LEU E 2 124 ? 139.839 155.061 112.002 1.00 22.26  ? 99  LEU E CG  1 
ATOM   11714 C CD1 . LEU E 2 124 ? 140.608 155.914 111.008 1.00 28.68  ? 99  LEU E CD1 1 
ATOM   11715 C CD2 . LEU E 2 124 ? 139.830 155.706 113.377 1.00 24.11  ? 99  LEU E CD2 1 
ATOM   11716 N N   . ASN E 2 125 ? 136.880 152.685 113.471 1.00 14.54  ? 100 ASN E N   1 
ATOM   11717 C CA  . ASN E 2 125 ? 136.863 152.109 114.806 1.00 12.28  ? 100 ASN E CA  1 
ATOM   11718 C C   . ASN E 2 125 ? 136.064 150.813 114.887 1.00 16.12  ? 100 ASN E C   1 
ATOM   11719 O O   . ASN E 2 125 ? 135.830 150.315 115.991 1.00 19.25  ? 100 ASN E O   1 
ATOM   11720 C CB  . ASN E 2 125 ? 136.322 153.130 115.807 1.00 13.46  ? 100 ASN E CB  1 
ATOM   11721 C CG  . ASN E 2 125 ? 134.857 153.437 115.590 1.00 17.22  ? 100 ASN E CG  1 
ATOM   11722 O OD1 . ASN E 2 125 ? 134.353 153.350 114.471 1.00 19.82  ? 100 ASN E OD1 1 
ATOM   11723 N ND2 . ASN E 2 125 ? 134.164 153.801 116.662 1.00 17.37  ? 100 ASN E ND2 1 
ATOM   11724 N N   . ASP E 2 126 ? 135.635 150.255 113.758 1.00 17.21  ? 101 ASP E N   1 
ATOM   11725 C CA  . ASP E 2 126 ? 134.875 149.012 113.801 1.00 16.09  ? 101 ASP E CA  1 
ATOM   11726 C C   . ASP E 2 126 ? 135.771 147.819 114.121 1.00 15.27  ? 101 ASP E C   1 
ATOM   11727 O O   . ASP E 2 126 ? 136.943 147.774 113.736 1.00 16.33  ? 101 ASP E O   1 
ATOM   11728 C CB  . ASP E 2 126 ? 134.131 148.791 112.480 1.00 14.48  ? 101 ASP E CB  1 
ATOM   11729 C CG  . ASP E 2 126 ? 134.984 148.118 111.414 1.00 16.17  ? 101 ASP E CG  1 
ATOM   11730 O OD1 . ASP E 2 126 ? 136.184 148.437 111.296 1.00 19.84  ? 101 ASP E OD1 1 
ATOM   11731 O OD2 . ASP E 2 126 ? 134.443 147.262 110.684 1.00 16.54  ? 101 ASP E OD2 1 
ATOM   11732 N N   . LYS E 2 127 ? 135.224 146.864 114.873 1.00 16.35  ? 102 LYS E N   1 
ATOM   11733 C CA  . LYS E 2 127 ? 135.958 145.646 115.195 1.00 17.13  ? 102 LYS E CA  1 
ATOM   11734 C C   . LYS E 2 127 ? 135.660 144.537 114.193 1.00 18.59  ? 102 LYS E C   1 
ATOM   11735 O O   . LYS E 2 127 ? 136.574 143.848 113.731 1.00 23.35  ? 102 LYS E O   1 
ATOM   11736 C CB  . LYS E 2 127 ? 135.614 145.180 116.612 1.00 17.02  ? 102 LYS E CB  1 
ATOM   11737 C CG  . LYS E 2 127 ? 135.899 146.201 117.696 1.00 18.15  ? 102 LYS E CG  1 
ATOM   11738 C CD  . LYS E 2 127 ? 135.516 145.658 119.059 1.00 21.33  ? 102 LYS E CD  1 
ATOM   11739 C CE  . LYS E 2 127 ? 136.441 144.534 119.483 1.00 30.64  ? 102 LYS E CE  1 
ATOM   11740 N NZ  . LYS E 2 127 ? 136.198 144.121 120.891 1.00 39.56  ? 102 LYS E NZ  1 
ATOM   11741 N N   . LYS E 2 128 ? 134.384 144.342 113.871 1.00 15.23  ? 103 LYS E N   1 
ATOM   11742 C CA  . LYS E 2 128 ? 133.973 143.341 112.897 1.00 14.41  ? 103 LYS E CA  1 
ATOM   11743 C C   . LYS E 2 128 ? 132.627 143.770 112.340 1.00 15.12  ? 103 LYS E C   1 
ATOM   11744 O O   . LYS E 2 128 ? 131.740 144.158 113.105 1.00 15.38  ? 103 LYS E O   1 
ATOM   11745 C CB  . LYS E 2 128 ? 133.889 141.950 113.529 1.00 16.26  ? 103 LYS E CB  1 
ATOM   11746 C CG  . LYS E 2 128 ? 133.616 140.835 112.539 1.00 19.07  ? 103 LYS E CG  1 
ATOM   11747 C CD  . LYS E 2 128 ? 133.718 139.473 113.202 1.00 22.25  ? 103 LYS E CD  1 
ATOM   11748 C CE  . LYS E 2 128 ? 133.475 138.357 112.202 1.00 26.77  ? 103 LYS E CE  1 
ATOM   11749 N NZ  . LYS E 2 128 ? 133.562 137.012 112.833 1.00 33.89  ? 103 LYS E NZ  1 
ATOM   11750 N N   . SER E 2 129 ? 132.470 143.699 111.022 1.00 15.07  ? 104 SER E N   1 
ATOM   11751 C CA  . SER E 2 129 ? 131.230 144.136 110.403 1.00 12.81  ? 104 SER E CA  1 
ATOM   11752 C C   . SER E 2 129 ? 130.974 143.329 109.141 1.00 13.63  ? 104 SER E C   1 
ATOM   11753 O O   . SER E 2 129 ? 131.888 142.741 108.557 1.00 14.92  ? 104 SER E O   1 
ATOM   11754 C CB  . SER E 2 129 ? 131.268 145.636 110.095 1.00 12.34  ? 104 SER E CB  1 
ATOM   11755 O OG  . SER E 2 129 ? 132.304 145.943 109.184 1.00 11.24  ? 104 SER E OG  1 
ATOM   11756 N N   . PHE E 2 130 ? 129.709 143.306 108.726 1.00 11.98  ? 105 PHE E N   1 
ATOM   11757 C CA  . PHE E 2 130 ? 129.317 142.592 107.523 1.00 13.77  ? 105 PHE E CA  1 
ATOM   11758 C C   . PHE E 2 130 ? 128.085 143.254 106.927 1.00 11.92  ? 105 PHE E C   1 
ATOM   11759 O O   . PHE E 2 130 ? 127.339 143.956 107.612 1.00 11.95  ? 105 PHE E O   1 
ATOM   11760 C CB  . PHE E 2 130 ? 129.046 141.109 107.809 1.00 14.06  ? 105 PHE E CB  1 
ATOM   11761 C CG  . PHE E 2 130 ? 127.895 140.868 108.746 1.00 15.91  ? 105 PHE E CG  1 
ATOM   11762 C CD1 . PHE E 2 130 ? 128.077 140.928 110.117 1.00 16.38  ? 105 PHE E CD1 1 
ATOM   11763 C CD2 . PHE E 2 130 ? 126.638 140.562 108.255 1.00 16.17  ? 105 PHE E CD2 1 
ATOM   11764 C CE1 . PHE E 2 130 ? 127.023 140.701 110.980 1.00 16.75  ? 105 PHE E CE1 1 
ATOM   11765 C CE2 . PHE E 2 130 ? 125.581 140.333 109.113 1.00 19.03  ? 105 PHE E CE2 1 
ATOM   11766 C CZ  . PHE E 2 130 ? 125.774 140.403 110.477 1.00 20.42  ? 105 PHE E CZ  1 
ATOM   11767 N N   . VAL E 2 131 ? 127.881 143.012 105.636 1.00 12.07  ? 106 VAL E N   1 
ATOM   11768 C CA  . VAL E 2 131 ? 126.685 143.440 104.921 1.00 10.62  ? 106 VAL E CA  1 
ATOM   11769 C C   . VAL E 2 131 ? 125.762 142.239 104.798 1.00 12.63  ? 106 VAL E C   1 
ATOM   11770 O O   . VAL E 2 131 ? 126.180 141.170 104.335 1.00 15.88  ? 106 VAL E O   1 
ATOM   11771 C CB  . VAL E 2 131 ? 127.031 144.017 103.540 1.00 10.73  ? 106 VAL E CB  1 
ATOM   11772 C CG1 . VAL E 2 131 ? 125.763 144.405 102.800 1.00 11.62  ? 106 VAL E CG1 1 
ATOM   11773 C CG2 . VAL E 2 131 ? 127.959 145.212 103.683 1.00 9.00   ? 106 VAL E CG2 1 
ATOM   11774 N N   . HIS E 2 132 ? 124.510 142.410 105.210 1.00 11.94  ? 107 HIS E N   1 
ATOM   11775 C CA  . HIS E 2 132 ? 123.576 141.295 105.255 1.00 14.04  ? 107 HIS E CA  1 
ATOM   11776 C C   . HIS E 2 132 ? 123.300 140.765 103.853 1.00 12.22  ? 107 HIS E C   1 
ATOM   11777 O O   . HIS E 2 132 ? 123.327 141.504 102.866 1.00 12.38  ? 107 HIS E O   1 
ATOM   11778 C CB  . HIS E 2 132 ? 122.272 141.734 105.912 1.00 12.15  ? 107 HIS E CB  1 
ATOM   11779 C CG  . HIS E 2 132 ? 122.432 142.171 107.333 1.00 10.16  ? 107 HIS E CG  1 
ATOM   11780 N ND1 . HIS E 2 132 ? 122.047 141.393 108.402 1.00 12.00  ? 107 HIS E ND1 1 
ATOM   11781 C CD2 . HIS E 2 132 ? 122.929 143.315 107.859 1.00 9.38   ? 107 HIS E CD2 1 
ATOM   11782 C CE1 . HIS E 2 132 ? 122.304 142.037 109.526 1.00 10.51  ? 107 HIS E CE1 1 
ATOM   11783 N NE2 . HIS E 2 132 ? 122.839 143.206 109.224 1.00 9.21   ? 107 HIS E NE2 1 
ATOM   11784 N N   . GLY E 2 133 ? 123.041 139.462 103.771 1.00 9.94   ? 108 GLY E N   1 
ATOM   11785 C CA  . GLY E 2 133 ? 122.990 138.787 102.490 1.00 10.74  ? 108 GLY E CA  1 
ATOM   11786 C C   . GLY E 2 133 ? 121.855 137.797 102.333 1.00 12.98  ? 108 GLY E C   1 
ATOM   11787 O O   . GLY E 2 133 ? 121.970 136.841 101.561 1.00 14.44  ? 108 GLY E O   1 
ATOM   11788 N N   . VAL E 2 134 ? 120.757 138.003 103.057 1.00 11.88  ? 109 VAL E N   1 
ATOM   11789 C CA  . VAL E 2 134 ? 119.554 137.190 102.915 1.00 9.62   ? 109 VAL E CA  1 
ATOM   11790 C C   . VAL E 2 134 ? 118.381 138.128 102.669 1.00 9.13   ? 109 VAL E C   1 
ATOM   11791 O O   . VAL E 2 134 ? 118.217 139.116 103.392 1.00 10.27  ? 109 VAL E O   1 
ATOM   11792 C CB  . VAL E 2 134 ? 119.312 136.323 104.167 1.00 9.82   ? 109 VAL E CB  1 
ATOM   11793 C CG1 . VAL E 2 134 ? 118.040 135.499 104.036 1.00 8.66   ? 109 VAL E CG1 1 
ATOM   11794 C CG2 . VAL E 2 134 ? 120.507 135.414 104.416 1.00 11.64  ? 109 VAL E CG2 1 
ATOM   11795 N N   . THR E 2 135 ? 117.565 137.825 101.657 1.00 9.52   ? 110 THR E N   1 
ATOM   11796 C CA  . THR E 2 135 ? 117.735 136.669 100.776 1.00 10.25  ? 110 THR E CA  1 
ATOM   11797 C C   . THR E 2 135 ? 118.846 136.922 99.762  1.00 11.06  ? 110 THR E C   1 
ATOM   11798 O O   . THR E 2 135 ? 119.447 135.987 99.236  1.00 12.03  ? 110 THR E O   1 
ATOM   11799 C CB  . THR E 2 135 ? 116.433 136.336 100.031 1.00 8.33   ? 110 THR E CB  1 
ATOM   11800 O OG1 . THR E 2 135 ? 116.082 137.423 99.167  1.00 7.99   ? 110 THR E OG1 1 
ATOM   11801 C CG2 . THR E 2 135 ? 115.306 136.109 101.019 1.00 7.19   ? 110 THR E CG2 1 
ATOM   11802 N N   . VAL E 2 136 ? 119.108 138.199 99.494  1.00 8.99   ? 111 VAL E N   1 
ATOM   11803 C CA  . VAL E 2 136 ? 120.228 138.619 98.669  1.00 9.87   ? 111 VAL E CA  1 
ATOM   11804 C C   . VAL E 2 136 ? 121.025 139.643 99.465  1.00 11.51  ? 111 VAL E C   1 
ATOM   11805 O O   . VAL E 2 136 ? 120.632 140.054 100.557 1.00 12.15  ? 111 VAL E O   1 
ATOM   11806 C CB  . VAL E 2 136 ? 119.782 139.210 97.319  1.00 11.13  ? 111 VAL E CB  1 
ATOM   11807 C CG1 . VAL E 2 136 ? 119.284 138.111 96.395  1.00 10.39  ? 111 VAL E CG1 1 
ATOM   11808 C CG2 . VAL E 2 136 ? 118.718 140.257 97.539  1.00 11.16  ? 111 VAL E CG2 1 
ATOM   11809 N N   . LYS E 2 137 ? 122.169 140.037 98.912  1.00 14.28  ? 112 LYS E N   1 
ATOM   11810 C CA  . LYS E 2 137 ? 122.972 141.079 99.536  1.00 14.93  ? 112 LYS E CA  1 
ATOM   11811 C C   . LYS E 2 137 ? 122.182 142.374 99.671  1.00 16.70  ? 112 LYS E C   1 
ATOM   11812 O O   . LYS E 2 137 ? 121.621 142.879 98.694  1.00 17.82  ? 112 LYS E O   1 
ATOM   11813 C CB  . LYS E 2 137 ? 124.242 141.322 98.721  1.00 19.46  ? 112 LYS E CB  1 
ATOM   11814 C CG  . LYS E 2 137 ? 125.302 142.121 99.459  1.00 25.44  ? 112 LYS E CG  1 
ATOM   11815 C CD  . LYS E 2 137 ? 126.658 142.009 98.787  1.00 35.08  ? 112 LYS E CD  1 
ATOM   11816 C CE  . LYS E 2 137 ? 127.745 142.634 99.643  1.00 29.77  ? 112 LYS E CE  1 
ATOM   11817 N NZ  . LYS E 2 137 ? 129.105 142.342 99.116  1.00 39.72  ? 112 LYS E NZ  1 
ATOM   11818 N N   . ASN E 2 138 ? 122.133 142.909 100.892 1.00 12.87  ? 113 ASN E N   1 
ATOM   11819 C CA  . ASN E 2 138 ? 121.372 144.125 101.180 1.00 10.22  ? 113 ASN E CA  1 
ATOM   11820 C C   . ASN E 2 138 ? 122.192 145.307 100.674 1.00 11.72  ? 113 ASN E C   1 
ATOM   11821 O O   . ASN E 2 138 ? 122.830 146.044 101.429 1.00 11.75  ? 113 ASN E O   1 
ATOM   11822 C CB  . ASN E 2 138 ? 121.043 144.240 102.664 1.00 9.73   ? 113 ASN E CB  1 
ATOM   11823 C CG  . ASN E 2 138 ? 120.210 143.077 103.177 1.00 9.98   ? 113 ASN E CG  1 
ATOM   11824 O OD1 . ASN E 2 138 ? 119.914 142.996 104.367 1.00 10.32  ? 113 ASN E OD1 1 
ATOM   11825 N ND2 . ASN E 2 138 ? 119.800 142.192 102.277 1.00 11.35  ? 113 ASN E ND2 1 
ATOM   11826 N N   . ARG E 2 139 ? 122.173 145.476 99.357  1.00 13.11  ? 114 ARG E N   1 
ATOM   11827 C CA  . ARG E 2 139 ? 122.957 146.488 98.668  1.00 14.55  ? 114 ARG E CA  1 
ATOM   11828 C C   . ARG E 2 139 ? 122.077 147.164 97.630  1.00 15.87  ? 114 ARG E C   1 
ATOM   11829 O O   . ARG E 2 139 ? 121.240 146.511 97.001  1.00 20.70  ? 114 ARG E O   1 
ATOM   11830 C CB  . ARG E 2 139 ? 124.197 145.864 98.014  1.00 19.62  ? 114 ARG E CB  1 
ATOM   11831 C CG  . ARG E 2 139 ? 125.023 146.810 97.172  1.00 23.08  ? 114 ARG E CG  1 
ATOM   11832 C CD  . ARG E 2 139 ? 126.294 146.128 96.697  1.00 29.04  ? 114 ARG E CD  1 
ATOM   11833 N NE  . ARG E 2 139 ? 126.012 144.897 95.968  1.00 36.60  ? 114 ARG E NE  1 
ATOM   11834 C CZ  . ARG E 2 139 ? 126.930 144.007 95.616  1.00 36.13  ? 114 ARG E CZ  1 
ATOM   11835 N NH1 . ARG E 2 139 ? 128.206 144.170 95.924  1.00 31.33  ? 114 ARG E NH1 1 
ATOM   11836 N NH2 . ARG E 2 139 ? 126.556 142.921 94.945  1.00 36.03  ? 114 ARG E NH2 1 
ATOM   11837 N N   . MET E 2 140 ? 122.242 148.473 97.473  1.00 14.33  ? 115 MET E N   1 
ATOM   11838 C CA  . MET E 2 140 ? 121.414 149.246 96.561  1.00 15.57  ? 115 MET E CA  1 
ATOM   11839 C C   . MET E 2 140 ? 122.280 150.148 95.696  1.00 19.81  ? 115 MET E C   1 
ATOM   11840 O O   . MET E 2 140 ? 123.202 150.802 96.189  1.00 20.58  ? 115 MET E O   1 
ATOM   11841 C CB  . MET E 2 140 ? 120.393 150.089 97.330  1.00 14.62  ? 115 MET E CB  1 
ATOM   11842 C CG  . MET E 2 140 ? 119.558 151.007 96.457  1.00 21.97  ? 115 MET E CG  1 
ATOM   11843 S SD  . MET E 2 140 ? 118.532 152.128 97.425  1.00 40.04  ? 115 MET E SD  1 
ATOM   11844 C CE  . MET E 2 140 ? 119.781 153.017 98.346  1.00 32.58  ? 115 MET E CE  1 
ATOM   11845 N N   . ILE E 2 141 ? 121.975 150.173 94.401  1.00 26.59  ? 116 ILE E N   1 
ATOM   11846 C CA  . ILE E 2 141 ? 122.586 151.092 93.449  1.00 26.19  ? 116 ILE E CA  1 
ATOM   11847 C C   . ILE E 2 141 ? 121.463 151.786 92.697  1.00 31.39  ? 116 ILE E C   1 
ATOM   11848 O O   . ILE E 2 141 ? 120.681 151.129 91.999  1.00 38.61  ? 116 ILE E O   1 
ATOM   11849 C CB  . ILE E 2 141 ? 123.518 150.371 92.459  1.00 24.64  ? 116 ILE E CB  1 
ATOM   11850 C CG1 . ILE E 2 141 ? 124.858 150.037 93.105  1.00 31.05  ? 116 ILE E CG1 1 
ATOM   11851 C CG2 . ILE E 2 141 ? 123.752 151.232 91.227  1.00 25.79  ? 116 ILE E CG2 1 
ATOM   11852 C CD1 . ILE E 2 141 ? 125.750 151.241 93.248  1.00 33.87  ? 116 ILE E CD1 1 
ATOM   11853 N N   . ARG E 2 142 ? 121.372 153.104 92.846  1.00 26.41  ? 117 ARG E N   1 
ATOM   11854 C CA  . ARG E 2 142 ? 120.366 153.891 92.147  1.00 29.11  ? 117 ARG E CA  1 
ATOM   11855 C C   . ARG E 2 142 ? 121.075 155.019 91.417  1.00 33.76  ? 117 ARG E C   1 
ATOM   11856 O O   . ARG E 2 142 ? 121.801 155.801 92.038  1.00 37.36  ? 117 ARG E O   1 
ATOM   11857 C CB  . ARG E 2 142 ? 119.316 154.435 93.119  1.00 33.75  ? 117 ARG E CB  1 
ATOM   11858 C CG  . ARG E 2 142 ? 118.085 155.011 92.443  1.00 44.15  ? 117 ARG E CG  1 
ATOM   11859 C CD  . ARG E 2 142 ? 117.087 155.535 93.462  1.00 42.38  ? 117 ARG E CD  1 
ATOM   11860 N NE  . ARG E 2 142 ? 116.648 154.491 94.380  1.00 34.73  ? 117 ARG E NE  1 
ATOM   11861 C CZ  . ARG E 2 142 ? 115.926 154.708 95.471  1.00 36.56  ? 117 ARG E CZ  1 
ATOM   11862 N NH1 . ARG E 2 142 ? 115.550 155.928 95.820  1.00 40.58  ? 117 ARG E NH1 1 
ATOM   11863 N NH2 . ARG E 2 142 ? 115.573 153.676 96.231  1.00 34.57  ? 117 ARG E NH2 1 
ATOM   11864 N N   . LEU E 2 143 ? 120.867 155.102 90.111  1.00 39.94  ? 118 LEU E N   1 
ATOM   11865 C CA  . LEU E 2 143 ? 121.470 156.135 89.285  1.00 42.28  ? 118 LEU E CA  1 
ATOM   11866 C C   . LEU E 2 143 ? 120.470 157.254 89.030  1.00 49.79  ? 118 LEU E C   1 
ATOM   11867 O O   . LEU E 2 143 ? 119.256 157.071 89.142  1.00 54.46  ? 118 LEU E O   1 
ATOM   11868 C CB  . LEU E 2 143 ? 121.963 155.550 87.960  1.00 45.65  ? 118 LEU E CB  1 
ATOM   11869 C CG  . LEU E 2 143 ? 122.884 154.336 88.085  1.00 40.02  ? 118 LEU E CG  1 
ATOM   11870 C CD1 . LEU E 2 143 ? 123.238 153.783 86.713  1.00 47.79  ? 118 LEU E CD1 1 
ATOM   11871 C CD2 . LEU E 2 143 ? 124.137 154.697 88.865  1.00 36.33  ? 118 LEU E CD2 1 
ATOM   11872 N N   . HIS E 2 144 ? 120.992 158.422 88.690  1.00 53.70  ? 119 HIS E N   1 
ATOM   11873 C CA  . HIS E 2 144 ? 120.167 159.559 88.321  1.00 59.40  ? 119 HIS E CA  1 
ATOM   11874 C C   . HIS E 2 144 ? 120.661 160.131 87.001  1.00 63.99  ? 119 HIS E C   1 
ATOM   11875 O O   . HIS E 2 144 ? 121.827 159.946 86.636  1.00 58.42  ? 119 HIS E O   1 
ATOM   11876 C CB  . HIS E 2 144 ? 120.203 160.633 89.420  1.00 52.85  ? 119 HIS E CB  1 
ATOM   11877 C CG  . HIS E 2 144 ? 119.731 160.147 90.757  1.00 54.42  ? 119 HIS E CG  1 
ATOM   11878 N ND1 . HIS E 2 144 ? 120.374 159.150 91.459  1.00 47.77  ? 119 HIS E ND1 1 
ATOM   11879 C CD2 . HIS E 2 144 ? 118.677 160.521 91.519  1.00 57.55  ? 119 HIS E CD2 1 
ATOM   11880 C CE1 . HIS E 2 144 ? 119.738 158.932 92.596  1.00 45.10  ? 119 HIS E CE1 1 
ATOM   11881 N NE2 . HIS E 2 144 ? 118.704 159.751 92.657  1.00 53.34  ? 119 HIS E NE2 1 
ATOM   11882 N N   . PRO E 2 145 ? 119.789 160.820 86.251  1.00 74.30  ? 120 PRO E N   1 
ATOM   11883 C CA  . PRO E 2 145 ? 120.167 161.224 84.881  1.00 72.57  ? 120 PRO E CA  1 
ATOM   11884 C C   . PRO E 2 145 ? 121.432 162.062 84.802  1.00 63.23  ? 120 PRO E C   1 
ATOM   11885 O O   . PRO E 2 145 ? 122.232 161.884 83.874  1.00 64.14  ? 120 PRO E O   1 
ATOM   11886 C CB  . PRO E 2 145 ? 118.934 161.999 84.394  1.00 75.98  ? 120 PRO E CB  1 
ATOM   11887 C CG  . PRO E 2 145 ? 117.811 161.504 85.242  1.00 74.93  ? 120 PRO E CG  1 
ATOM   11888 C CD  . PRO E 2 145 ? 118.406 161.208 86.579  1.00 72.32  ? 120 PRO E CD  1 
ATOM   11889 N N   . ASP E 2 146 ? 121.639 162.974 85.752  1.00 62.49  ? 121 ASP E N   1 
ATOM   11890 C CA  . ASP E 2 146 ? 122.786 163.874 85.705  1.00 66.97  ? 121 ASP E CA  1 
ATOM   11891 C C   . ASP E 2 146 ? 124.110 163.180 85.998  1.00 68.13  ? 121 ASP E C   1 
ATOM   11892 O O   . ASP E 2 146 ? 125.166 163.783 85.780  1.00 64.21  ? 121 ASP E O   1 
ATOM   11893 C CB  . ASP E 2 146 ? 122.571 165.038 86.678  1.00 65.56  ? 121 ASP E CB  1 
ATOM   11894 C CG  . ASP E 2 146 ? 122.339 164.577 88.111  1.00 68.39  ? 121 ASP E CG  1 
ATOM   11895 O OD1 . ASP E 2 146 ? 122.594 163.395 88.424  1.00 67.31  ? 121 ASP E OD1 1 
ATOM   11896 O OD2 . ASP E 2 146 ? 121.895 165.408 88.931  1.00 70.85  ? 121 ASP E OD2 1 
ATOM   11897 N N   . GLY E 2 147 ? 124.080 161.939 86.478  1.00 67.30  ? 122 GLY E N   1 
ATOM   11898 C CA  . GLY E 2 147 ? 125.276 161.217 86.864  1.00 63.28  ? 122 GLY E CA  1 
ATOM   11899 C C   . GLY E 2 147 ? 125.409 160.982 88.352  1.00 55.44  ? 122 GLY E C   1 
ATOM   11900 O O   . GLY E 2 147 ? 126.392 160.365 88.779  1.00 52.51  ? 122 GLY E O   1 
ATOM   11901 N N   . THR E 2 148 ? 124.462 161.462 89.153  1.00 52.37  ? 123 THR E N   1 
ATOM   11902 C CA  . THR E 2 148 ? 124.496 161.233 90.590  1.00 44.72  ? 123 THR E CA  1 
ATOM   11903 C C   . THR E 2 148 ? 124.321 159.750 90.885  1.00 41.92  ? 123 THR E C   1 
ATOM   11904 O O   . THR E 2 148 ? 123.487 159.076 90.277  1.00 51.44  ? 123 THR E O   1 
ATOM   11905 C CB  . THR E 2 148 ? 123.396 162.036 91.283  1.00 48.91  ? 123 THR E CB  1 
ATOM   11906 O OG1 . THR E 2 148 ? 123.484 163.411 90.888  1.00 55.05  ? 123 THR E OG1 1 
ATOM   11907 C CG2 . THR E 2 148 ? 123.531 161.938 92.796  1.00 44.38  ? 123 THR E CG2 1 
ATOM   11908 N N   . VAL E 2 149 ? 125.109 159.240 91.827  1.00 34.36  ? 124 VAL E N   1 
ATOM   11909 C CA  . VAL E 2 149 ? 125.053 157.835 92.209  1.00 33.49  ? 124 VAL E CA  1 
ATOM   11910 C C   . VAL E 2 149 ? 124.623 157.760 93.664  1.00 29.92  ? 124 VAL E C   1 
ATOM   11911 O O   . VAL E 2 149 ? 125.201 158.432 94.525  1.00 34.03  ? 124 VAL E O   1 
ATOM   11912 C CB  . VAL E 2 149 ? 126.406 157.133 91.999  1.00 32.83  ? 124 VAL E CB  1 
ATOM   11913 C CG1 . VAL E 2 149 ? 126.274 155.641 92.245  1.00 28.19  ? 124 VAL E CG1 1 
ATOM   11914 C CG2 . VAL E 2 149 ? 126.928 157.397 90.599  1.00 34.88  ? 124 VAL E CG2 1 
ATOM   11915 N N   . LEU E 2 150 ? 123.605 156.950 93.932  1.00 25.24  ? 125 LEU E N   1 
ATOM   11916 C CA  . LEU E 2 150 ? 123.149 156.654 95.282  1.00 24.44  ? 125 LEU E CA  1 
ATOM   11917 C C   . LEU E 2 150 ? 123.520 155.217 95.614  1.00 24.74  ? 125 LEU E C   1 
ATOM   11918 O O   . LEU E 2 150 ? 123.001 154.281 94.998  1.00 32.42  ? 125 LEU E O   1 
ATOM   11919 C CB  . LEU E 2 150 ? 121.640 156.869 95.402  1.00 33.22  ? 125 LEU E CB  1 
ATOM   11920 C CG  . LEU E 2 150 ? 120.900 156.321 96.626  1.00 34.02  ? 125 LEU E CG  1 
ATOM   11921 C CD1 . LEU E 2 150 ? 121.593 156.707 97.920  1.00 29.86  ? 125 LEU E CD1 1 
ATOM   11922 C CD2 . LEU E 2 150 ? 119.460 156.807 96.627  1.00 33.31  ? 125 LEU E CD2 1 
ATOM   11923 N N   . TYR E 2 151 ? 124.408 155.046 96.588  1.00 22.13  ? 126 TYR E N   1 
ATOM   11924 C CA  . TYR E 2 151 ? 124.931 153.735 96.955  1.00 20.41  ? 126 TYR E CA  1 
ATOM   11925 C C   . TYR E 2 151 ? 124.551 153.479 98.405  1.00 19.50  ? 126 TYR E C   1 
ATOM   11926 O O   . TYR E 2 151 ? 125.124 154.082 99.318  1.00 24.25  ? 126 TYR E O   1 
ATOM   11927 C CB  . TYR E 2 151 ? 126.444 153.675 96.746  1.00 22.10  ? 126 TYR E CB  1 
ATOM   11928 C CG  . TYR E 2 151 ? 127.069 152.323 97.009  1.00 19.58  ? 126 TYR E CG  1 
ATOM   11929 C CD1 . TYR E 2 151 ? 126.522 151.167 96.476  1.00 18.89  ? 126 TYR E CD1 1 
ATOM   11930 C CD2 . TYR E 2 151 ? 128.230 152.210 97.760  1.00 22.43  ? 126 TYR E CD2 1 
ATOM   11931 C CE1 . TYR E 2 151 ? 127.096 149.933 96.702  1.00 20.64  ? 126 TYR E CE1 1 
ATOM   11932 C CE2 . TYR E 2 151 ? 128.816 150.980 97.989  1.00 23.82  ? 126 TYR E CE2 1 
ATOM   11933 C CZ  . TYR E 2 151 ? 128.243 149.845 97.460  1.00 22.63  ? 126 TYR E CZ  1 
ATOM   11934 O OH  . TYR E 2 151 ? 128.819 148.616 97.686  1.00 21.31  ? 126 TYR E OH  1 
ATOM   11935 N N   . GLY E 2 152 ? 123.588 152.591 98.613  1.00 17.32  ? 127 GLY E N   1 
ATOM   11936 C CA  . GLY E 2 152 ? 123.067 152.294 99.938  1.00 14.89  ? 127 GLY E CA  1 
ATOM   11937 C C   . GLY E 2 152 ? 123.407 150.872 100.344 1.00 11.50  ? 127 GLY E C   1 
ATOM   11938 O O   . GLY E 2 152 ? 123.354 149.953 99.523  1.00 17.66  ? 127 GLY E O   1 
ATOM   11939 N N   . LEU E 2 153 ? 123.750 150.701 101.615 1.00 8.23   ? 128 LEU E N   1 
ATOM   11940 C CA  . LEU E 2 153 ? 124.047 149.394 102.173 1.00 9.06   ? 128 LEU E CA  1 
ATOM   11941 C C   . LEU E 2 153 ? 123.337 149.247 103.508 1.00 9.79   ? 128 LEU E C   1 
ATOM   11942 O O   . LEU E 2 153 ? 123.136 150.225 104.231 1.00 12.71  ? 128 LEU E O   1 
ATOM   11943 C CB  . LEU E 2 153 ? 125.558 149.176 102.360 1.00 12.21  ? 128 LEU E CB  1 
ATOM   11944 C CG  . LEU E 2 153 ? 126.453 149.243 101.120 1.00 14.29  ? 128 LEU E CG  1 
ATOM   11945 C CD1 . LEU E 2 153 ? 126.914 150.669 100.866 1.00 16.99  ? 128 LEU E CD1 1 
ATOM   11946 C CD2 . LEU E 2 153 ? 127.644 148.310 101.254 1.00 11.98  ? 128 LEU E CD2 1 
ATOM   11947 N N   . ARG E 2 154 ? 122.954 148.017 103.828 1.00 7.55   ? 129 ARG E N   1 
ATOM   11948 C CA  . ARG E 2 154 ? 122.481 147.679 105.161 1.00 6.87   ? 129 ARG E CA  1 
ATOM   11949 C C   . ARG E 2 154 ? 123.608 146.950 105.871 1.00 7.20   ? 129 ARG E C   1 
ATOM   11950 O O   . ARG E 2 154 ? 124.007 145.857 105.457 1.00 10.53  ? 129 ARG E O   1 
ATOM   11951 C CB  . ARG E 2 154 ? 121.228 146.807 105.104 1.00 8.86   ? 129 ARG E CB  1 
ATOM   11952 C CG  . ARG E 2 154 ? 120.570 146.586 106.450 1.00 10.92  ? 129 ARG E CG  1 
ATOM   11953 C CD  . ARG E 2 154 ? 119.115 146.194 106.301 1.00 12.22  ? 129 ARG E CD  1 
ATOM   11954 N NE  . ARG E 2 154 ? 118.602 145.583 107.520 1.00 12.91  ? 129 ARG E NE  1 
ATOM   11955 C CZ  . ARG E 2 154 ? 118.597 144.279 107.757 1.00 11.85  ? 129 ARG E CZ  1 
ATOM   11956 N NH1 . ARG E 2 154 ? 119.071 143.414 106.877 1.00 10.65  ? 129 ARG E NH1 1 
ATOM   11957 N NH2 . ARG E 2 154 ? 118.104 143.831 108.908 1.00 11.29  ? 129 ARG E NH2 1 
ATOM   11958 N N   . ILE E 2 155 ? 124.107 147.551 106.943 1.00 6.47   ? 130 ILE E N   1 
ATOM   11959 C CA  . ILE E 2 155 ? 125.327 147.105 107.596 1.00 8.56   ? 130 ILE E CA  1 
ATOM   11960 C C   . ILE E 2 155 ? 125.047 146.908 109.074 1.00 8.32   ? 130 ILE E C   1 
ATOM   11961 O O   . ILE E 2 155 ? 124.442 147.771 109.717 1.00 12.33  ? 130 ILE E O   1 
ATOM   11962 C CB  . ILE E 2 155 ? 126.484 148.106 107.396 1.00 8.23   ? 130 ILE E CB  1 
ATOM   11963 C CG1 . ILE E 2 155 ? 126.795 148.283 105.910 1.00 7.99   ? 130 ILE E CG1 1 
ATOM   11964 C CG2 . ILE E 2 155 ? 127.724 147.648 108.142 1.00 9.10   ? 130 ILE E CG2 1 
ATOM   11965 C CD1 . ILE E 2 155 ? 127.594 149.525 105.597 1.00 6.98   ? 130 ILE E CD1 1 
ATOM   11966 N N   . THR E 2 156 ? 125.487 145.778 109.609 1.00 8.06   ? 131 THR E N   1 
ATOM   11967 C CA  . THR E 2 156 ? 125.592 145.593 111.045 1.00 10.22  ? 131 THR E CA  1 
ATOM   11968 C C   . THR E 2 156 ? 127.075 145.657 111.359 1.00 13.98  ? 131 THR E C   1 
ATOM   11969 O O   . THR E 2 156 ? 127.852 144.829 110.874 1.00 16.66  ? 131 THR E O   1 
ATOM   11970 C CB  . THR E 2 156 ? 124.993 144.259 111.488 1.00 14.62  ? 131 THR E CB  1 
ATOM   11971 O OG1 . THR E 2 156 ? 123.585 144.252 111.224 1.00 19.60  ? 131 THR E OG1 1 
ATOM   11972 C CG2 . THR E 2 156 ? 125.232 144.028 112.965 1.00 13.68  ? 131 THR E CG2 1 
ATOM   11973 N N   . THR E 2 157 ? 127.463 146.633 112.170 1.00 13.88  ? 132 THR E N   1 
ATOM   11974 C CA  . THR E 2 157 ? 128.864 146.862 112.478 1.00 13.85  ? 132 THR E CA  1 
ATOM   11975 C C   . THR E 2 157 ? 129.074 146.906 113.979 1.00 12.51  ? 132 THR E C   1 
ATOM   11976 O O   . THR E 2 157 ? 128.336 147.585 114.699 1.00 15.28  ? 132 THR E O   1 
ATOM   11977 C CB  . THR E 2 157 ? 129.362 148.165 111.833 1.00 14.83  ? 132 THR E CB  1 
ATOM   11978 O OG1 . THR E 2 157 ? 130.683 148.461 112.301 1.00 17.80  ? 132 THR E OG1 1 
ATOM   11979 C CG2 . THR E 2 157 ? 128.434 149.329 112.151 1.00 12.52  ? 132 THR E CG2 1 
ATOM   11980 N N   . THR E 2 158 ? 130.064 146.161 114.448 1.00 11.80  ? 133 THR E N   1 
ATOM   11981 C CA  . THR E 2 158 ? 130.524 146.281 115.820 1.00 14.30  ? 133 THR E CA  1 
ATOM   11982 C C   . THR E 2 158 ? 131.649 147.307 115.830 1.00 14.43  ? 133 THR E C   1 
ATOM   11983 O O   . THR E 2 158 ? 132.698 147.087 115.215 1.00 18.92  ? 133 THR E O   1 
ATOM   11984 C CB  . THR E 2 158 ? 131.002 144.931 116.347 1.00 17.85  ? 133 THR E CB  1 
ATOM   11985 O OG1 . THR E 2 158 ? 129.906 144.008 116.367 1.00 20.81  ? 133 THR E OG1 1 
ATOM   11986 C CG2 . THR E 2 158 ? 131.547 145.074 117.741 1.00 17.88  ? 133 THR E CG2 1 
ATOM   11987 N N   . ALA E 2 159 ? 131.437 148.418 116.523 1.00 13.97  ? 134 ALA E N   1 
ATOM   11988 C CA  . ALA E 2 159 ? 132.375 149.529 116.510 1.00 16.04  ? 134 ALA E CA  1 
ATOM   11989 C C   . ALA E 2 159 ? 132.996 149.682 117.888 1.00 17.81  ? 134 ALA E C   1 
ATOM   11990 O O   . ALA E 2 159 ? 132.316 149.514 118.902 1.00 21.96  ? 134 ALA E O   1 
ATOM   11991 C CB  . ALA E 2 159 ? 131.685 150.830 116.095 1.00 17.10  ? 134 ALA E CB  1 
ATOM   11992 N N   . ALA E 2 160 ? 134.277 150.030 117.923 1.00 16.47  ? 135 ALA E N   1 
ATOM   11993 C CA  . ALA E 2 160 ? 134.953 150.204 119.199 1.00 17.01  ? 135 ALA E CA  1 
ATOM   11994 C C   . ALA E 2 160 ? 134.516 151.507 119.852 1.00 20.94  ? 135 ALA E C   1 
ATOM   11995 O O   . ALA E 2 160 ? 134.571 152.576 119.237 1.00 23.30  ? 135 ALA E O   1 
ATOM   11996 C CB  . ALA E 2 160 ? 136.469 150.186 119.016 1.00 16.07  ? 135 ALA E CB  1 
ATOM   11997 N N   . CYS E 2 161 ? 134.079 151.412 121.104 1.00 24.99  ? 136 CYS E N   1 
ATOM   11998 C CA  . CYS E 2 161 ? 133.734 152.572 121.921 1.00 30.21  ? 136 CYS E CA  1 
ATOM   11999 C C   . CYS E 2 161 ? 134.482 152.434 123.238 1.00 34.73  ? 136 CYS E C   1 
ATOM   12000 O O   . CYS E 2 161 ? 134.057 151.687 124.123 1.00 37.95  ? 136 CYS E O   1 
ATOM   12001 C CB  . CYS E 2 161 ? 132.229 152.673 122.160 1.00 27.99  ? 136 CYS E CB  1 
ATOM   12002 S SG  . CYS E 2 161 ? 131.751 154.121 123.150 1.00 47.27  ? 136 CYS E SG  1 
ATOM   12003 N N   . MET E 2 162 ? 135.598 153.145 123.365 1.00 32.28  ? 137 MET E N   1 
ATOM   12004 C CA  . MET E 2 162 ? 136.352 153.106 124.609 1.00 31.86  ? 137 MET E CA  1 
ATOM   12005 C C   . MET E 2 162 ? 135.550 153.858 125.659 1.00 32.55  ? 137 MET E C   1 
ATOM   12006 O O   . MET E 2 162 ? 135.387 155.079 125.570 1.00 32.98  ? 137 MET E O   1 
ATOM   12007 C CB  . MET E 2 162 ? 137.738 153.714 124.422 1.00 33.46  ? 137 MET E CB  1 
ATOM   12008 C CG  . MET E 2 162 ? 138.676 153.441 125.583 1.00 41.23  ? 137 MET E CG  1 
ATOM   12009 S SD  . MET E 2 162 ? 139.117 151.697 125.711 1.00 61.96  ? 137 MET E SD  1 
ATOM   12010 C CE  . MET E 2 162 ? 139.756 151.628 127.382 1.00 37.98  ? 137 MET E CE  1 
ATOM   12011 N N   . MET E 2 163 ? 135.045 153.137 126.649 1.00 34.88  ? 138 MET E N   1 
ATOM   12012 C CA  . MET E 2 163 ? 134.144 153.710 127.633 1.00 36.06  ? 138 MET E CA  1 
ATOM   12013 C C   . MET E 2 163 ? 134.896 154.062 128.906 1.00 35.32  ? 138 MET E C   1 
ATOM   12014 O O   . MET E 2 163 ? 135.814 153.347 129.318 1.00 31.46  ? 138 MET E O   1 
ATOM   12015 C CB  . MET E 2 163 ? 133.005 152.742 127.956 1.00 32.95  ? 138 MET E CB  1 
ATOM   12016 C CG  . MET E 2 163 ? 132.193 152.310 126.750 1.00 33.72  ? 138 MET E CG  1 
ATOM   12017 S SD  . MET E 2 163 ? 130.726 151.375 127.214 1.00 55.61  ? 138 MET E SD  1 
ATOM   12018 C CE  . MET E 2 163 ? 130.289 150.640 125.643 1.00 36.08  ? 138 MET E CE  1 
ATOM   12019 N N   . ASP E 2 164 ? 134.507 155.175 129.518 1.00 35.77  ? 139 ASP E N   1 
ATOM   12020 C CA  . ASP E 2 164 ? 135.072 155.610 130.786 1.00 36.81  ? 139 ASP E CA  1 
ATOM   12021 C C   . ASP E 2 164 ? 134.107 155.139 131.867 1.00 34.47  ? 139 ASP E C   1 
ATOM   12022 O O   . ASP E 2 164 ? 132.992 155.658 131.982 1.00 35.07  ? 139 ASP E O   1 
ATOM   12023 C CB  . ASP E 2 164 ? 135.257 157.126 130.815 1.00 40.91  ? 139 ASP E CB  1 
ATOM   12024 C CG  . ASP E 2 164 ? 135.917 157.611 132.089 1.00 41.80  ? 139 ASP E CG  1 
ATOM   12025 O OD1 . ASP E 2 164 ? 136.462 156.772 132.835 1.00 43.06  ? 139 ASP E OD1 1 
ATOM   12026 O OD2 . ASP E 2 164 ? 135.892 158.833 132.344 1.00 39.26  ? 139 ASP E OD2 1 
ATOM   12027 N N   . LEU E 2 165 ? 134.536 154.159 132.659 1.00 30.65  ? 140 LEU E N   1 
ATOM   12028 C CA  . LEU E 2 165 ? 133.674 153.514 133.640 1.00 28.86  ? 140 LEU E CA  1 
ATOM   12029 C C   . LEU E 2 165 ? 134.050 153.884 135.067 1.00 33.77  ? 140 LEU E C   1 
ATOM   12030 O O   . LEU E 2 165 ? 133.726 153.147 136.001 1.00 37.10  ? 140 LEU E O   1 
ATOM   12031 C CB  . LEU E 2 165 ? 133.683 151.998 133.446 1.00 26.30  ? 140 LEU E CB  1 
ATOM   12032 C CG  . LEU E 2 165 ? 133.181 151.553 132.069 1.00 23.79  ? 140 LEU E CG  1 
ATOM   12033 C CD1 . LEU E 2 165 ? 133.263 150.048 131.899 1.00 24.97  ? 140 LEU E CD1 1 
ATOM   12034 C CD2 . LEU E 2 165 ? 131.760 152.035 131.848 1.00 27.36  ? 140 LEU E CD2 1 
ATOM   12035 N N   . ARG E 2 166 ? 134.703 155.030 135.254 1.00 32.06  ? 141 ARG E N   1 
ATOM   12036 C CA  . ARG E 2 166 ? 134.985 155.520 136.598 1.00 30.04  ? 141 ARG E CA  1 
ATOM   12037 C C   . ARG E 2 166 ? 133.701 155.834 137.354 1.00 30.00  ? 141 ARG E C   1 
ATOM   12038 O O   . ARG E 2 166 ? 133.594 155.547 138.551 1.00 35.02  ? 141 ARG E O   1 
ATOM   12039 C CB  . ARG E 2 166 ? 135.890 156.750 136.535 1.00 36.11  ? 141 ARG E CB  1 
ATOM   12040 C CG  . ARG E 2 166 ? 137.258 156.475 135.941 1.00 46.43  ? 141 ARG E CG  1 
ATOM   12041 C CD  . ARG E 2 166 ? 138.221 157.612 136.227 1.00 53.19  ? 141 ARG E CD  1 
ATOM   12042 N NE  . ARG E 2 166 ? 139.519 157.396 135.599 1.00 67.58  ? 141 ARG E NE  1 
ATOM   12043 C CZ  . ARG E 2 166 ? 139.884 157.917 134.436 1.00 68.21  ? 141 ARG E CZ  1 
ATOM   12044 N NH1 . ARG E 2 166 ? 139.072 158.698 133.742 1.00 66.59  ? 141 ARG E NH1 1 
ATOM   12045 N NH2 . ARG E 2 166 ? 141.096 157.650 133.957 1.00 69.00  ? 141 ARG E NH2 1 
ATOM   12046 N N   . ARG E 2 167 ? 132.720 156.430 136.685 1.00 28.80  ? 142 ARG E N   1 
ATOM   12047 C CA  . ARG E 2 167 ? 131.490 156.838 137.346 1.00 28.74  ? 142 ARG E CA  1 
ATOM   12048 C C   . ARG E 2 167 ? 130.384 155.793 137.229 1.00 27.62  ? 142 ARG E C   1 
ATOM   12049 O O   . ARG E 2 167 ? 129.247 156.069 137.618 1.00 27.98  ? 142 ARG E O   1 
ATOM   12050 C CB  . ARG E 2 167 ? 131.016 158.167 136.756 1.00 27.71  ? 142 ARG E CB  1 
ATOM   12051 C CG  . ARG E 2 167 ? 132.101 159.233 136.731 1.00 30.72  ? 142 ARG E CG  1 
ATOM   12052 C CD  . ARG E 2 167 ? 131.636 160.507 136.045 1.00 37.47  ? 142 ARG E CD  1 
ATOM   12053 N NE  . ARG E 2 167 ? 130.804 161.341 136.902 1.00 40.09  ? 142 ARG E NE  1 
ATOM   12054 C CZ  . ARG E 2 167 ? 131.281 162.250 137.741 1.00 36.68  ? 142 ARG E CZ  1 
ATOM   12055 N NH1 . ARG E 2 167 ? 132.581 162.448 137.878 1.00 31.47  ? 142 ARG E NH1 1 
ATOM   12056 N NH2 . ARG E 2 167 ? 130.432 162.980 138.458 1.00 34.68  ? 142 ARG E NH2 1 
ATOM   12057 N N   . TYR E 2 168 ? 130.698 154.610 136.708 1.00 25.16  ? 143 TYR E N   1 
ATOM   12058 C CA  . TYR E 2 168 ? 129.713 153.546 136.556 1.00 22.89  ? 143 TYR E CA  1 
ATOM   12059 C C   . TYR E 2 168 ? 129.119 153.174 137.915 1.00 27.78  ? 143 TYR E C   1 
ATOM   12060 O O   . TYR E 2 168 ? 129.853 153.070 138.903 1.00 33.33  ? 143 TYR E O   1 
ATOM   12061 C CB  . TYR E 2 168 ? 130.372 152.326 135.908 1.00 22.50  ? 143 TYR E CB  1 
ATOM   12062 C CG  . TYR E 2 168 ? 129.505 151.092 135.791 1.00 23.18  ? 143 TYR E CG  1 
ATOM   12063 C CD1 . TYR E 2 168 ? 129.462 150.148 136.810 1.00 24.49  ? 143 TYR E CD1 1 
ATOM   12064 C CD2 . TYR E 2 168 ? 128.751 150.857 134.653 1.00 21.91  ? 143 TYR E CD2 1 
ATOM   12065 C CE1 . TYR E 2 168 ? 128.679 149.016 136.703 1.00 25.97  ? 143 TYR E CE1 1 
ATOM   12066 C CE2 . TYR E 2 168 ? 127.965 149.728 134.538 1.00 21.68  ? 143 TYR E CE2 1 
ATOM   12067 C CZ  . TYR E 2 168 ? 127.933 148.812 135.564 1.00 25.42  ? 143 TYR E CZ  1 
ATOM   12068 O OH  . TYR E 2 168 ? 127.152 147.688 135.448 1.00 31.67  ? 143 TYR E OH  1 
ATOM   12069 N N   . PRO E 2 169 ? 127.798 152.938 138.001 1.00 24.86  ? 144 PRO E N   1 
ATOM   12070 C CA  . PRO E 2 169 ? 126.807 152.938 136.922 1.00 21.93  ? 144 PRO E CA  1 
ATOM   12071 C C   . PRO E 2 169 ? 126.161 154.296 136.709 1.00 22.53  ? 144 PRO E C   1 
ATOM   12072 O O   . PRO E 2 169 ? 125.161 154.405 136.007 1.00 26.32  ? 144 PRO E O   1 
ATOM   12073 C CB  . PRO E 2 169 ? 125.789 151.912 137.420 1.00 22.23  ? 144 PRO E CB  1 
ATOM   12074 C CG  . PRO E 2 169 ? 125.767 152.152 138.904 1.00 21.04  ? 144 PRO E CG  1 
ATOM   12075 C CD  . PRO E 2 169 ? 127.191 152.523 139.279 1.00 24.33  ? 144 PRO E CD  1 
ATOM   12076 N N   . LEU E 2 170 ? 126.705 155.357 137.303 1.00 23.29  ? 145 LEU E N   1 
ATOM   12077 C CA  . LEU E 2 170 ? 126.221 156.711 137.069 1.00 23.18  ? 145 LEU E CA  1 
ATOM   12078 C C   . LEU E 2 170 ? 126.951 157.380 135.918 1.00 23.84  ? 145 LEU E C   1 
ATOM   12079 O O   . LEU E 2 170 ? 127.069 158.612 135.887 1.00 26.26  ? 145 LEU E O   1 
ATOM   12080 C CB  . LEU E 2 170 ? 126.351 157.546 138.342 1.00 22.80  ? 145 LEU E CB  1 
ATOM   12081 C CG  . LEU E 2 170 ? 125.626 157.025 139.583 1.00 21.50  ? 145 LEU E CG  1 
ATOM   12082 C CD1 . LEU E 2 170 ? 126.556 156.197 140.454 1.00 20.49  ? 145 LEU E CD1 1 
ATOM   12083 C CD2 . LEU E 2 170 ? 125.039 158.175 140.369 1.00 22.81  ? 145 LEU E CD2 1 
ATOM   12084 N N   . ASP E 2 171 ? 127.437 156.595 134.967 1.00 22.52  ? 146 ASP E N   1 
ATOM   12085 C CA  . ASP E 2 171 ? 128.342 157.080 133.942 1.00 21.56  ? 146 ASP E CA  1 
ATOM   12086 C C   . ASP E 2 171 ? 127.577 157.527 132.708 1.00 19.93  ? 146 ASP E C   1 
ATOM   12087 O O   . ASP E 2 171 ? 126.460 157.082 132.435 1.00 20.87  ? 146 ASP E O   1 
ATOM   12088 C CB  . ASP E 2 171 ? 129.352 155.999 133.559 1.00 22.14  ? 146 ASP E CB  1 
ATOM   12089 C CG  . ASP E 2 171 ? 128.685 154.722 133.098 1.00 22.55  ? 146 ASP E CG  1 
ATOM   12090 O OD1 . ASP E 2 171 ? 127.638 154.361 133.672 1.00 26.22  ? 146 ASP E OD1 1 
ATOM   12091 O OD2 . ASP E 2 171 ? 129.200 154.082 132.159 1.00 22.09  ? 146 ASP E OD2 1 
ATOM   12092 N N   . GLU E 2 172 ? 128.204 158.423 131.959 1.00 24.42  ? 147 GLU E N   1 
ATOM   12093 C CA  . GLU E 2 172 ? 127.702 158.876 130.674 1.00 22.68  ? 147 GLU E CA  1 
ATOM   12094 C C   . GLU E 2 172 ? 128.791 158.608 129.650 1.00 21.50  ? 147 GLU E C   1 
ATOM   12095 O O   . GLU E 2 172 ? 129.943 159.006 129.846 1.00 27.70  ? 147 GLU E O   1 
ATOM   12096 C CB  . GLU E 2 172 ? 127.336 160.361 130.722 1.00 25.55  ? 147 GLU E CB  1 
ATOM   12097 C CG  . GLU E 2 172 ? 126.640 160.889 129.485 1.00 28.95  ? 147 GLU E CG  1 
ATOM   12098 C CD  . GLU E 2 172 ? 126.254 162.347 129.630 1.00 46.84  ? 147 GLU E CD  1 
ATOM   12099 O OE1 . GLU E 2 172 ? 126.909 163.059 130.420 1.00 59.94  ? 147 GLU E OE1 1 
ATOM   12100 O OE2 . GLU E 2 172 ? 125.281 162.777 128.975 1.00 43.33  ? 147 GLU E OE2 1 
ATOM   12101 N N   . GLN E 2 173 ? 128.427 157.945 128.561 1.00 18.26  ? 148 GLN E N   1 
ATOM   12102 C CA  . GLN E 2 173 ? 129.391 157.546 127.552 1.00 18.60  ? 148 GLN E CA  1 
ATOM   12103 C C   . GLN E 2 173 ? 129.191 158.348 126.279 1.00 18.35  ? 148 GLN E C   1 
ATOM   12104 O O   . GLN E 2 173 ? 128.150 158.969 126.057 1.00 22.00  ? 148 GLN E O   1 
ATOM   12105 C CB  . GLN E 2 173 ? 129.280 156.048 127.239 1.00 19.81  ? 148 GLN E CB  1 
ATOM   12106 C CG  . GLN E 2 173 ? 129.364 155.125 128.444 1.00 22.97  ? 148 GLN E CG  1 
ATOM   12107 C CD  . GLN E 2 173 ? 130.630 155.317 129.261 1.00 27.93  ? 148 GLN E CD  1 
ATOM   12108 O OE1 . GLN E 2 173 ? 131.632 155.842 128.774 1.00 27.20  ? 148 GLN E OE1 1 
ATOM   12109 N NE2 . GLN E 2 173 ? 130.588 154.890 130.516 1.00 31.89  ? 148 GLN E NE2 1 
ATOM   12110 N N   . ASN E 2 174 ? 130.218 158.317 125.438 1.00 17.55  ? 149 ASN E N   1 
ATOM   12111 C CA  . ASN E 2 174 ? 130.183 158.975 124.141 1.00 20.87  ? 149 ASN E CA  1 
ATOM   12112 C C   . ASN E 2 174 ? 130.810 158.001 123.158 1.00 23.10  ? 149 ASN E C   1 
ATOM   12113 O O   . ASN E 2 174 ? 132.030 157.814 123.155 1.00 25.42  ? 149 ASN E O   1 
ATOM   12114 C CB  . ASN E 2 174 ? 130.938 160.309 124.191 1.00 20.98  ? 149 ASN E CB  1 
ATOM   12115 C CG  . ASN E 2 174 ? 131.179 160.930 122.816 1.00 25.19  ? 149 ASN E CG  1 
ATOM   12116 O OD1 . ASN E 2 174 ? 130.801 160.389 121.778 1.00 27.64  ? 149 ASN E OD1 1 
ATOM   12117 N ND2 . ASN E 2 174 ? 131.827 162.090 122.818 1.00 29.93  ? 149 ASN E ND2 1 
ATOM   12118 N N   . CYS E 2 175 ? 129.975 157.389 122.328 1.00 20.66  ? 150 CYS E N   1 
ATOM   12119 C CA  . CYS E 2 175 ? 130.410 156.412 121.345 1.00 25.10  ? 150 CYS E CA  1 
ATOM   12120 C C   . CYS E 2 175 ? 130.335 157.030 119.963 1.00 25.38  ? 150 CYS E C   1 
ATOM   12121 O O   . CYS E 2 175 ? 129.357 157.703 119.622 1.00 26.88  ? 150 CYS E O   1 
ATOM   12122 C CB  . CYS E 2 175 ? 129.583 155.127 121.405 1.00 26.95  ? 150 CYS E CB  1 
ATOM   12123 S SG  . CYS E 2 175 ? 129.732 154.277 122.972 1.00 31.20  ? 150 CYS E SG  1 
ATOM   12124 N N   . THR E 2 176 ? 131.370 156.790 119.174 1.00 23.77  ? 151 THR E N   1 
ATOM   12125 C CA  . THR E 2 176 ? 131.528 157.424 117.883 1.00 22.10  ? 151 THR E CA  1 
ATOM   12126 C C   . THR E 2 176 ? 131.530 156.375 116.785 1.00 18.68  ? 151 THR E C   1 
ATOM   12127 O O   . THR E 2 176 ? 131.658 155.173 117.029 1.00 20.29  ? 151 THR E O   1 
ATOM   12128 C CB  . THR E 2 176 ? 132.820 158.248 117.825 1.00 28.28  ? 151 THR E CB  1 
ATOM   12129 O OG1 . THR E 2 176 ? 133.950 157.370 117.874 1.00 32.34  ? 151 THR E OG1 1 
ATOM   12130 C CG2 . THR E 2 176 ? 132.891 159.214 118.995 1.00 23.74  ? 151 THR E CG2 1 
ATOM   12131 N N   . LEU E 2 177 ? 131.371 156.861 115.561 1.00 18.33  ? 152 LEU E N   1 
ATOM   12132 C CA  . LEU E 2 177 ? 131.541 156.055 114.360 1.00 19.93  ? 152 LEU E CA  1 
ATOM   12133 C C   . LEU E 2 177 ? 132.345 156.899 113.387 1.00 19.10  ? 152 LEU E C   1 
ATOM   12134 O O   . LEU E 2 177 ? 131.841 157.897 112.864 1.00 22.02  ? 152 LEU E O   1 
ATOM   12135 C CB  . LEU E 2 177 ? 130.192 155.651 113.767 1.00 17.52  ? 152 LEU E CB  1 
ATOM   12136 C CG  . LEU E 2 177 ? 130.196 154.703 112.569 1.00 16.75  ? 152 LEU E CG  1 
ATOM   12137 C CD1 . LEU E 2 177 ? 130.635 153.311 112.979 1.00 16.11  ? 152 LEU E CD1 1 
ATOM   12138 C CD2 . LEU E 2 177 ? 128.820 154.665 111.935 1.00 19.94  ? 152 LEU E CD2 1 
ATOM   12139 N N   . GLU E 2 178 ? 133.587 156.500 113.144 1.00 15.47  ? 153 GLU E N   1 
ATOM   12140 C CA  . GLU E 2 178 ? 134.509 157.266 112.320 1.00 15.40  ? 153 GLU E CA  1 
ATOM   12141 C C   . GLU E 2 178 ? 134.446 156.732 110.900 1.00 17.08  ? 153 GLU E C   1 
ATOM   12142 O O   . GLU E 2 178 ? 134.645 155.535 110.672 1.00 21.85  ? 153 GLU E O   1 
ATOM   12143 C CB  . GLU E 2 178 ? 135.938 157.180 112.857 1.00 20.40  ? 153 GLU E CB  1 
ATOM   12144 C CG  . GLU E 2 178 ? 136.085 157.413 114.349 1.00 26.21  ? 153 GLU E CG  1 
ATOM   12145 C CD  . GLU E 2 178 ? 135.727 158.826 114.755 1.00 31.78  ? 153 GLU E CD  1 
ATOM   12146 O OE1 . GLU E 2 178 ? 135.881 159.742 113.920 1.00 32.60  ? 153 GLU E OE1 1 
ATOM   12147 O OE2 . GLU E 2 178 ? 135.306 159.024 115.913 1.00 32.24  ? 153 GLU E OE2 1 
ATOM   12148 N N   . ILE E 2 179 ? 134.169 157.617 109.951 1.00 15.20  ? 154 ILE E N   1 
ATOM   12149 C CA  . ILE E 2 179 ? 134.036 157.248 108.552 1.00 17.54  ? 154 ILE E CA  1 
ATOM   12150 C C   . ILE E 2 179 ? 135.172 157.924 107.803 1.00 22.08  ? 154 ILE E C   1 
ATOM   12151 O O   . ILE E 2 179 ? 135.236 159.157 107.734 1.00 29.41  ? 154 ILE E O   1 
ATOM   12152 C CB  . ILE E 2 179 ? 132.668 157.669 107.996 1.00 17.53  ? 154 ILE E CB  1 
ATOM   12153 C CG1 . ILE E 2 179 ? 131.548 157.138 108.892 1.00 14.35  ? 154 ILE E CG1 1 
ATOM   12154 C CG2 . ILE E 2 179 ? 132.497 157.187 106.583 1.00 19.76  ? 154 ILE E CG2 1 
ATOM   12155 C CD1 . ILE E 2 179 ? 130.209 157.793 108.650 1.00 16.32  ? 154 ILE E CD1 1 
ATOM   12156 N N   . GLU E 2 180 ? 136.065 157.117 107.237 1.00 19.23  ? 155 GLU E N   1 
ATOM   12157 C CA  . GLU E 2 180 ? 137.273 157.630 106.614 1.00 22.44  ? 155 GLU E CA  1 
ATOM   12158 C C   . GLU E 2 180 ? 137.542 156.863 105.330 1.00 24.47  ? 155 GLU E C   1 
ATOM   12159 O O   . GLU E 2 180 ? 137.092 155.729 105.156 1.00 28.31  ? 155 GLU E O   1 
ATOM   12160 C CB  . GLU E 2 180 ? 138.468 157.516 107.575 1.00 27.08  ? 155 GLU E CB  1 
ATOM   12161 C CG  . GLU E 2 180 ? 139.762 158.139 107.081 1.00 37.32  ? 155 GLU E CG  1 
ATOM   12162 C CD  . GLU E 2 180 ? 140.748 158.390 108.202 1.00 43.23  ? 155 GLU E CD  1 
ATOM   12163 O OE1 . GLU E 2 180 ? 140.380 159.086 109.171 1.00 42.88  ? 155 GLU E OE1 1 
ATOM   12164 O OE2 . GLU E 2 180 ? 141.892 157.898 108.109 1.00 43.78  ? 155 GLU E OE2 1 
ATOM   12165 N N   . SER E 2 181 ? 138.280 157.497 104.424 1.00 24.22  ? 156 SER E N   1 
ATOM   12166 C CA  . SER E 2 181 ? 138.744 156.824 103.223 1.00 24.94  ? 156 SER E CA  1 
ATOM   12167 C C   . SER E 2 181 ? 140.032 156.078 103.537 1.00 29.74  ? 156 SER E C   1 
ATOM   12168 O O   . SER E 2 181 ? 140.925 156.609 104.203 1.00 37.57  ? 156 SER E O   1 
ATOM   12169 C CB  . SER E 2 181 ? 138.972 157.827 102.094 1.00 29.32  ? 156 SER E CB  1 
ATOM   12170 O OG  . SER E 2 181 ? 139.463 157.181 100.934 1.00 35.34  ? 156 SER E OG  1 
ATOM   12171 N N   . TYR E 2 182 ? 140.129 154.836 103.063 1.00 27.95  ? 157 TYR E N   1 
ATOM   12172 C CA  . TYR E 2 182 ? 141.274 154.011 103.433 1.00 27.47  ? 157 TYR E CA  1 
ATOM   12173 C C   . TYR E 2 182 ? 142.514 154.379 102.628 1.00 28.75  ? 157 TYR E C   1 
ATOM   12174 O O   . TYR E 2 182 ? 143.597 154.567 103.193 1.00 29.91  ? 157 TYR E O   1 
ATOM   12175 C CB  . TYR E 2 182 ? 140.946 152.528 103.262 1.00 25.81  ? 157 TYR E CB  1 
ATOM   12176 C CG  . TYR E 2 182 ? 141.956 151.633 103.939 1.00 25.26  ? 157 TYR E CG  1 
ATOM   12177 C CD1 . TYR E 2 182 ? 141.803 151.269 105.268 1.00 23.28  ? 157 TYR E CD1 1 
ATOM   12178 C CD2 . TYR E 2 182 ? 143.071 151.167 103.257 1.00 22.49  ? 157 TYR E CD2 1 
ATOM   12179 C CE1 . TYR E 2 182 ? 142.724 150.461 105.896 1.00 19.92  ? 157 TYR E CE1 1 
ATOM   12180 C CE2 . TYR E 2 182 ? 143.999 150.358 103.878 1.00 20.91  ? 157 TYR E CE2 1 
ATOM   12181 C CZ  . TYR E 2 182 ? 143.820 150.009 105.197 1.00 19.07  ? 157 TYR E CZ  1 
ATOM   12182 O OH  . TYR E 2 182 ? 144.741 149.203 105.822 1.00 22.26  ? 157 TYR E OH  1 
ATOM   12183 N N   . GLY E 2 183 ? 142.375 154.493 101.312 1.00 28.71  ? 158 GLY E N   1 
ATOM   12184 C CA  . GLY E 2 183 ? 143.521 154.676 100.445 1.00 30.16  ? 158 GLY E CA  1 
ATOM   12185 C C   . GLY E 2 183 ? 143.674 156.087 99.920  1.00 37.54  ? 158 GLY E C   1 
ATOM   12186 O O   . GLY E 2 183 ? 144.797 156.571 99.757  1.00 42.56  ? 158 GLY E O   1 
ATOM   12187 N N   . TYR E 2 184 ? 142.559 156.764 99.666  1.00 36.49  ? 159 TYR E N   1 
ATOM   12188 C CA  . TYR E 2 184 ? 142.583 158.053 98.994  1.00 36.47  ? 159 TYR E CA  1 
ATOM   12189 C C   . TYR E 2 184 ? 142.730 159.174 100.012 1.00 36.76  ? 159 TYR E C   1 
ATOM   12190 O O   . TYR E 2 184 ? 142.093 159.161 101.069 1.00 36.21  ? 159 TYR E O   1 
ATOM   12191 C CB  . TYR E 2 184 ? 141.306 158.259 98.178  1.00 35.25  ? 159 TYR E CB  1 
ATOM   12192 C CG  . TYR E 2 184 ? 141.078 157.212 97.115  1.00 36.43  ? 159 TYR E CG  1 
ATOM   12193 C CD1 . TYR E 2 184 ? 141.818 157.210 95.944  1.00 41.13  ? 159 TYR E CD1 1 
ATOM   12194 C CD2 . TYR E 2 184 ? 140.114 156.230 97.281  1.00 34.41  ? 159 TYR E CD2 1 
ATOM   12195 C CE1 . TYR E 2 184 ? 141.610 156.253 94.971  1.00 43.64  ? 159 TYR E CE1 1 
ATOM   12196 C CE2 . TYR E 2 184 ? 139.897 155.271 96.314  1.00 32.51  ? 159 TYR E CE2 1 
ATOM   12197 C CZ  . TYR E 2 184 ? 140.648 155.287 95.161  1.00 38.02  ? 159 TYR E CZ  1 
ATOM   12198 O OH  . TYR E 2 184 ? 140.435 154.334 94.194  1.00 47.95  ? 159 TYR E OH  1 
ATOM   12199 N N   . THR E 2 185 ? 143.583 160.141 99.686  1.00 37.33  ? 160 THR E N   1 
ATOM   12200 C CA  . THR E 2 185 ? 143.788 161.312 100.520 1.00 42.21  ? 160 THR E CA  1 
ATOM   12201 C C   . THR E 2 185 ? 142.766 162.393 100.175 1.00 43.63  ? 160 THR E C   1 
ATOM   12202 O O   . THR E 2 185 ? 141.913 162.224 99.300  1.00 42.45  ? 160 THR E O   1 
ATOM   12203 C CB  . THR E 2 185 ? 145.214 161.837 100.359 1.00 45.37  ? 160 THR E CB  1 
ATOM   12204 O OG1 . THR E 2 185 ? 145.427 162.239 99.000  1.00 50.39  ? 160 THR E OG1 1 
ATOM   12205 C CG2 . THR E 2 185 ? 146.221 160.760 100.725 1.00 46.69  ? 160 THR E CG2 1 
ATOM   12206 N N   . THR E 2 186 ? 142.855 163.528 100.872 1.00 43.25  ? 161 THR E N   1 
ATOM   12207 C CA  . THR E 2 186 ? 141.944 164.637 100.616 1.00 42.72  ? 161 THR E CA  1 
ATOM   12208 C C   . THR E 2 186 ? 142.165 165.269 99.250  1.00 46.40  ? 161 THR E C   1 
ATOM   12209 O O   . THR E 2 186 ? 141.316 166.047 98.803  1.00 49.08  ? 161 THR E O   1 
ATOM   12210 C CB  . THR E 2 186 ? 142.089 165.705 101.701 1.00 41.01  ? 161 THR E CB  1 
ATOM   12211 O OG1 . THR E 2 186 ? 143.472 166.049 101.851 1.00 44.95  ? 161 THR E OG1 1 
ATOM   12212 C CG2 . THR E 2 186 ? 141.554 165.192 103.029 1.00 38.93  ? 161 THR E CG2 1 
ATOM   12213 N N   . ASP E 2 187 ? 143.281 164.963 98.587  1.00 49.17  ? 162 ASP E N   1 
ATOM   12214 C CA  . ASP E 2 187 ? 143.487 165.404 97.214  1.00 55.25  ? 162 ASP E CA  1 
ATOM   12215 C C   . ASP E 2 187 ? 142.618 164.637 96.228  1.00 55.44  ? 162 ASP E C   1 
ATOM   12216 O O   . ASP E 2 187 ? 142.413 165.108 95.105  1.00 61.32  ? 162 ASP E O   1 
ATOM   12217 C CB  . ASP E 2 187 ? 144.959 165.257 96.828  1.00 56.47  ? 162 ASP E CB  1 
ATOM   12218 C CG  . ASP E 2 187 ? 145.850 166.252 97.541  1.00 58.95  ? 162 ASP E CG  1 
ATOM   12219 O OD1 . ASP E 2 187 ? 145.363 167.351 97.879  1.00 59.45  ? 162 ASP E OD1 1 
ATOM   12220 O OD2 . ASP E 2 187 ? 147.037 165.935 97.764  1.00 56.22  ? 162 ASP E OD2 1 
ATOM   12221 N N   . ASP E 2 188 ? 142.106 163.473 96.620  1.00 49.30  ? 163 ASP E N   1 
ATOM   12222 C CA  . ASP E 2 188 ? 141.323 162.617 95.738  1.00 51.51  ? 163 ASP E CA  1 
ATOM   12223 C C   . ASP E 2 188 ? 139.853 162.534 96.111  1.00 49.03  ? 163 ASP E C   1 
ATOM   12224 O O   . ASP E 2 188 ? 139.002 162.510 95.219  1.00 54.05  ? 163 ASP E O   1 
ATOM   12225 C CB  . ASP E 2 188 ? 141.917 161.204 95.714  1.00 55.36  ? 163 ASP E CB  1 
ATOM   12226 C CG  . ASP E 2 188 ? 143.315 161.171 95.131  1.00 58.50  ? 163 ASP E CG  1 
ATOM   12227 O OD1 . ASP E 2 188 ? 143.592 161.963 94.206  1.00 61.86  ? 163 ASP E OD1 1 
ATOM   12228 O OD2 . ASP E 2 188 ? 144.136 160.351 95.594  1.00 53.00  ? 163 ASP E OD2 1 
ATOM   12229 N N   . ILE E 2 189 ? 139.521 162.481 97.398  1.00 44.02  ? 164 ILE E N   1 
ATOM   12230 C CA  . ILE E 2 189 ? 138.145 162.275 97.836  1.00 45.30  ? 164 ILE E CA  1 
ATOM   12231 C C   . ILE E 2 189 ? 137.868 163.183 99.028  1.00 43.10  ? 164 ILE E C   1 
ATOM   12232 O O   . ILE E 2 189 ? 138.722 163.359 99.903  1.00 49.62  ? 164 ILE E O   1 
ATOM   12233 C CB  . ILE E 2 189 ? 137.878 160.790 98.172  1.00 41.69  ? 164 ILE E CB  1 
ATOM   12234 C CG1 . ILE E 2 189 ? 136.377 160.511 98.239  1.00 40.84  ? 164 ILE E CG1 1 
ATOM   12235 C CG2 . ILE E 2 189 ? 138.562 160.378 99.467  1.00 42.37  ? 164 ILE E CG2 1 
ATOM   12236 C CD1 . ILE E 2 189 ? 136.043 159.037 98.299  1.00 38.69  ? 164 ILE E CD1 1 
ATOM   12237 N N   . GLU E 2 190 ? 136.685 163.793 99.039  1.00 40.91  ? 165 GLU E N   1 
ATOM   12238 C CA  . GLU E 2 190 ? 136.243 164.623 100.150 1.00 41.55  ? 165 GLU E CA  1 
ATOM   12239 C C   . GLU E 2 190 ? 134.873 164.156 100.620 1.00 37.84  ? 165 GLU E C   1 
ATOM   12240 O O   . GLU E 2 190 ? 134.021 163.794 99.804  1.00 42.50  ? 165 GLU E O   1 
ATOM   12241 C CB  . GLU E 2 190 ? 136.188 166.094 99.729  1.00 48.62  ? 165 GLU E CB  1 
ATOM   12242 C CG  . GLU E 2 190 ? 137.556 166.711 99.488  1.00 54.17  ? 165 GLU E CG  1 
ATOM   12243 C CD  . GLU E 2 190 ? 137.478 168.173 99.098  1.00 69.83  ? 165 GLU E CD  1 
ATOM   12244 O OE1 . GLU E 2 190 ? 136.375 168.635 98.737  1.00 73.70  ? 165 GLU E OE1 1 
ATOM   12245 O OE2 . GLU E 2 190 ? 138.522 168.858 99.142  1.00 72.08  ? 165 GLU E OE2 1 
ATOM   12246 N N   . PHE E 2 191 ? 134.663 164.165 101.933 1.00 30.83  ? 166 PHE E N   1 
ATOM   12247 C CA  . PHE E 2 191 ? 133.402 163.747 102.527 1.00 27.50  ? 166 PHE E CA  1 
ATOM   12248 C C   . PHE E 2 191 ? 132.621 164.946 103.054 1.00 30.38  ? 166 PHE E C   1 
ATOM   12249 O O   . PHE E 2 191 ? 133.203 165.969 103.425 1.00 39.48  ? 166 PHE E O   1 
ATOM   12250 C CB  . PHE E 2 191 ? 133.641 162.752 103.665 1.00 26.97  ? 166 PHE E CB  1 
ATOM   12251 C CG  . PHE E 2 191 ? 134.162 161.417 103.213 1.00 30.03  ? 166 PHE E CG  1 
ATOM   12252 C CD1 . PHE E 2 191 ? 134.124 161.053 101.878 1.00 35.57  ? 166 PHE E CD1 1 
ATOM   12253 C CD2 . PHE E 2 191 ? 134.685 160.521 104.129 1.00 28.01  ? 166 PHE E CD2 1 
ATOM   12254 C CE1 . PHE E 2 191 ? 134.605 159.825 101.465 1.00 33.99  ? 166 PHE E CE1 1 
ATOM   12255 C CE2 . PHE E 2 191 ? 135.164 159.293 103.723 1.00 30.87  ? 166 PHE E CE2 1 
ATOM   12256 C CZ  . PHE E 2 191 ? 135.124 158.944 102.388 1.00 31.60  ? 166 PHE E CZ  1 
ATOM   12257 N N   . TYR E 2 192 ? 131.294 164.813 103.087 1.00 32.32  ? 167 TYR E N   1 
ATOM   12258 C CA  . TYR E 2 192 ? 130.443 165.778 103.774 1.00 32.08  ? 167 TYR E CA  1 
ATOM   12259 C C   . TYR E 2 192 ? 129.139 165.100 104.174 1.00 30.42  ? 167 TYR E C   1 
ATOM   12260 O O   . TYR E 2 192 ? 128.682 164.169 103.508 1.00 33.78  ? 167 TYR E O   1 
ATOM   12261 C CB  . TYR E 2 192 ? 130.148 167.011 102.911 1.00 33.70  ? 167 TYR E CB  1 
ATOM   12262 C CG  . TYR E 2 192 ? 129.319 166.729 101.678 1.00 39.33  ? 167 TYR E CG  1 
ATOM   12263 C CD1 . TYR E 2 192 ? 129.901 166.235 100.519 1.00 41.65  ? 167 TYR E CD1 1 
ATOM   12264 C CD2 . TYR E 2 192 ? 127.949 166.960 101.675 1.00 33.88  ? 167 TYR E CD2 1 
ATOM   12265 C CE1 . TYR E 2 192 ? 129.141 165.981 99.389  1.00 41.77  ? 167 TYR E CE1 1 
ATOM   12266 C CE2 . TYR E 2 192 ? 127.182 166.706 100.554 1.00 34.53  ? 167 TYR E CE2 1 
ATOM   12267 C CZ  . TYR E 2 192 ? 127.782 166.217 99.415  1.00 40.65  ? 167 TYR E CZ  1 
ATOM   12268 O OH  . TYR E 2 192 ? 127.019 165.964 98.299  1.00 38.92  ? 167 TYR E OH  1 
ATOM   12269 N N   . TRP E 2 193 ? 128.547 165.577 105.268 1.00 24.66  ? 168 TRP E N   1 
ATOM   12270 C CA  . TRP E 2 193 ? 127.219 165.135 105.685 1.00 24.41  ? 168 TRP E CA  1 
ATOM   12271 C C   . TRP E 2 193 ? 126.143 165.754 104.801 1.00 30.44  ? 168 TRP E C   1 
ATOM   12272 O O   . TRP E 2 193 ? 126.036 166.981 104.710 1.00 34.08  ? 168 TRP E O   1 
ATOM   12273 C CB  . TRP E 2 193 ? 126.967 165.489 107.148 1.00 23.12  ? 168 TRP E CB  1 
ATOM   12274 C CG  . TRP E 2 193 ? 127.803 164.728 108.117 1.00 23.81  ? 168 TRP E CG  1 
ATOM   12275 C CD1 . TRP E 2 193 ? 128.848 165.202 108.850 1.00 24.50  ? 168 TRP E CD1 1 
ATOM   12276 C CD2 . TRP E 2 193 ? 127.629 163.361 108.501 1.00 22.98  ? 168 TRP E CD2 1 
ATOM   12277 N NE1 . TRP E 2 193 ? 129.354 164.206 109.648 1.00 24.67  ? 168 TRP E NE1 1 
ATOM   12278 C CE2 . TRP E 2 193 ? 128.620 163.066 109.453 1.00 23.30  ? 168 TRP E CE2 1 
ATOM   12279 C CE3 . TRP E 2 193 ? 126.738 162.354 108.121 1.00 22.60  ? 168 TRP E CE3 1 
ATOM   12280 C CZ2 . TRP E 2 193 ? 128.745 161.807 110.033 1.00 23.11  ? 168 TRP E CZ2 1 
ATOM   12281 C CZ3 . TRP E 2 193 ? 126.863 161.105 108.697 1.00 19.84  ? 168 TRP E CZ3 1 
ATOM   12282 C CH2 . TRP E 2 193 ? 127.858 160.842 109.642 1.00 19.84  ? 168 TRP E CH2 1 
ATOM   12283 N N   . ARG E 2 194 ? 125.353 164.906 104.145 1.00 33.87  ? 169 ARG E N   1 
ATOM   12284 C CA  . ARG E 2 194 ? 124.316 165.374 103.233 1.00 33.23  ? 169 ARG E CA  1 
ATOM   12285 C C   . ARG E 2 194 ? 123.059 165.745 104.010 1.00 34.00  ? 169 ARG E C   1 
ATOM   12286 O O   . ARG E 2 194 ? 122.420 164.878 104.616 1.00 31.74  ? 169 ARG E O   1 
ATOM   12287 C CB  . ARG E 2 194 ? 123.990 164.299 102.200 1.00 31.92  ? 169 ARG E CB  1 
ATOM   12288 C CG  . ARG E 2 194 ? 123.107 164.798 101.076 1.00 36.50  ? 169 ARG E CG  1 
ATOM   12289 C CD  . ARG E 2 194 ? 122.985 163.778 99.966  1.00 44.93  ? 169 ARG E CD  1 
ATOM   12290 N NE  . ARG E 2 194 ? 122.262 164.320 98.823  1.00 53.15  ? 169 ARG E NE  1 
ATOM   12291 C CZ  . ARG E 2 194 ? 120.948 164.244 98.667  1.00 53.87  ? 169 ARG E CZ  1 
ATOM   12292 N NH1 . ARG E 2 194 ? 120.179 163.654 99.568  1.00 51.63  ? 169 ARG E NH1 1 
ATOM   12293 N NH2 . ARG E 2 194 ? 120.391 164.776 97.583  1.00 56.42  ? 169 ARG E NH2 1 
ATOM   12294 N N   . GLY E 2 195 ? 122.697 167.024 103.986 1.00 36.39  ? 170 GLY E N   1 
ATOM   12295 C CA  . GLY E 2 195 ? 121.591 167.516 104.781 1.00 34.77  ? 170 GLY E CA  1 
ATOM   12296 C C   . GLY E 2 195 ? 121.948 168.098 106.129 1.00 36.25  ? 170 GLY E C   1 
ATOM   12297 O O   . GLY E 2 195 ? 121.046 168.301 106.950 1.00 35.13  ? 170 GLY E O   1 
ATOM   12298 N N   . GLY E 2 196 ? 123.222 168.382 106.382 1.00 37.78  ? 171 GLY E N   1 
ATOM   12299 C CA  . GLY E 2 196 ? 123.604 168.982 107.650 1.00 39.93  ? 171 GLY E CA  1 
ATOM   12300 C C   . GLY E 2 196 ? 123.292 168.072 108.822 1.00 42.71  ? 171 GLY E C   1 
ATOM   12301 O O   . GLY E 2 196 ? 123.551 166.865 108.793 1.00 41.67  ? 171 GLY E O   1 
ATOM   12302 N N   . ASP E 2 197 ? 122.718 168.660 109.874 1.00 44.19  ? 172 ASP E N   1 
ATOM   12303 C CA  . ASP E 2 197 ? 122.405 167.926 111.094 1.00 40.80  ? 172 ASP E CA  1 
ATOM   12304 C C   . ASP E 2 197 ? 121.212 166.992 110.942 1.00 38.87  ? 172 ASP E C   1 
ATOM   12305 O O   . ASP E 2 197 ? 120.928 166.225 111.868 1.00 38.61  ? 172 ASP E O   1 
ATOM   12306 C CB  . ASP E 2 197 ? 122.146 168.904 112.242 1.00 49.70  ? 172 ASP E CB  1 
ATOM   12307 C CG  . ASP E 2 197 ? 123.416 169.557 112.749 1.00 54.99  ? 172 ASP E CG  1 
ATOM   12308 O OD1 . ASP E 2 197 ? 124.511 169.010 112.498 1.00 45.82  ? 172 ASP E OD1 1 
ATOM   12309 O OD2 . ASP E 2 197 ? 123.320 170.618 113.401 1.00 67.00  ? 172 ASP E OD2 1 
ATOM   12310 N N   . LYS E 2 198 ? 120.512 167.038 109.812 1.00 36.74  ? 173 LYS E N   1 
ATOM   12311 C CA  . LYS E 2 198 ? 119.451 166.091 109.497 1.00 35.63  ? 173 LYS E CA  1 
ATOM   12312 C C   . LYS E 2 198 ? 119.954 164.876 108.728 1.00 35.01  ? 173 LYS E C   1 
ATOM   12313 O O   . LYS E 2 198 ? 119.142 164.059 108.284 1.00 34.71  ? 173 LYS E O   1 
ATOM   12314 C CB  . LYS E 2 198 ? 118.345 166.788 108.703 1.00 42.43  ? 173 LYS E CB  1 
ATOM   12315 C CG  . LYS E 2 198 ? 117.790 168.026 109.386 1.00 47.61  ? 173 LYS E CG  1 
ATOM   12316 C CD  . LYS E 2 198 ? 116.662 168.648 108.580 1.00 52.40  ? 173 LYS E CD  1 
ATOM   12317 C CE  . LYS E 2 198 ? 116.314 170.030 109.107 1.00 52.09  ? 173 LYS E CE  1 
ATOM   12318 N NZ  . LYS E 2 198 ? 115.997 169.997 110.560 1.00 55.20  ? 173 LYS E NZ  1 
ATOM   12319 N N   . ALA E 2 199 ? 121.271 164.746 108.558 1.00 34.17  ? 174 ALA E N   1 
ATOM   12320 C CA  . ALA E 2 199 ? 121.836 163.642 107.792 1.00 28.51  ? 174 ALA E CA  1 
ATOM   12321 C C   . ALA E 2 199 ? 121.675 162.291 108.477 1.00 29.31  ? 174 ALA E C   1 
ATOM   12322 O O   . ALA E 2 199 ? 121.822 161.261 107.814 1.00 30.40  ? 174 ALA E O   1 
ATOM   12323 C CB  . ALA E 2 199 ? 123.317 163.898 107.514 1.00 26.63  ? 174 ALA E CB  1 
ATOM   12324 N N   . VAL E 2 200 ? 121.373 162.255 109.771 1.00 29.10  ? 175 VAL E N   1 
ATOM   12325 C CA  . VAL E 2 200 ? 121.171 160.997 110.481 1.00 24.73  ? 175 VAL E CA  1 
ATOM   12326 C C   . VAL E 2 200 ? 119.762 160.979 111.052 1.00 30.28  ? 175 VAL E C   1 
ATOM   12327 O O   . VAL E 2 200 ? 119.372 161.894 111.788 1.00 35.29  ? 175 VAL E O   1 
ATOM   12328 C CB  . VAL E 2 200 ? 122.211 160.797 111.593 1.00 22.17  ? 175 VAL E CB  1 
ATOM   12329 C CG1 . VAL E 2 200 ? 121.827 159.622 112.470 1.00 24.53  ? 175 VAL E CG1 1 
ATOM   12330 C CG2 . VAL E 2 200 ? 123.585 160.584 110.994 1.00 20.14  ? 175 VAL E CG2 1 
ATOM   12331 N N   . THR E 2 201 ? 119.003 159.939 110.713 1.00 28.30  ? 176 THR E N   1 
ATOM   12332 C CA  . THR E 2 201 ? 117.624 159.784 111.147 1.00 32.61  ? 176 THR E CA  1 
ATOM   12333 C C   . THR E 2 201 ? 117.460 158.415 111.794 1.00 35.30  ? 176 THR E C   1 
ATOM   12334 O O   . THR E 2 201 ? 118.286 157.518 111.610 1.00 35.21  ? 176 THR E O   1 
ATOM   12335 C CB  . THR E 2 201 ? 116.645 159.940 109.972 1.00 33.75  ? 176 THR E CB  1 
ATOM   12336 O OG1 . THR E 2 201 ? 117.133 160.946 109.078 1.00 35.52  ? 176 THR E OG1 1 
ATOM   12337 C CG2 . THR E 2 201 ? 115.265 160.352 110.467 1.00 36.83  ? 176 THR E CG2 1 
ATOM   12338 N N   . GLY E 2 202 ? 116.383 158.260 112.563 1.00 37.32  ? 177 GLY E N   1 
ATOM   12339 C CA  . GLY E 2 202 ? 116.092 157.013 113.234 1.00 38.61  ? 177 GLY E CA  1 
ATOM   12340 C C   . GLY E 2 202 ? 116.604 156.921 114.653 1.00 39.72  ? 177 GLY E C   1 
ATOM   12341 O O   . GLY E 2 202 ? 116.313 155.931 115.337 1.00 39.83  ? 177 GLY E O   1 
ATOM   12342 N N   . VAL E 2 203 ? 117.361 157.917 115.113 1.00 41.36  ? 178 VAL E N   1 
ATOM   12343 C CA  . VAL E 2 203 ? 117.936 157.874 116.453 1.00 45.69  ? 178 VAL E CA  1 
ATOM   12344 C C   . VAL E 2 203 ? 116.843 157.896 117.516 1.00 50.98  ? 178 VAL E C   1 
ATOM   12345 O O   . VAL E 2 203 ? 116.924 157.186 118.526 1.00 47.11  ? 178 VAL E O   1 
ATOM   12346 C CB  . VAL E 2 203 ? 118.929 159.035 116.634 1.00 42.53  ? 178 VAL E CB  1 
ATOM   12347 C CG1 . VAL E 2 203 ? 119.505 159.021 118.029 1.00 41.34  ? 178 VAL E CG1 1 
ATOM   12348 C CG2 . VAL E 2 203 ? 120.034 158.947 115.596 1.00 35.25  ? 178 VAL E CG2 1 
ATOM   12349 N N   . GLU E 2 204 ? 115.806 158.712 117.306 1.00 56.33  ? 179 GLU E N   1 
ATOM   12350 C CA  . GLU E 2 204 ? 114.722 158.811 118.280 1.00 52.31  ? 179 GLU E CA  1 
ATOM   12351 C C   . GLU E 2 204 ? 114.004 157.481 118.482 1.00 51.33  ? 179 GLU E C   1 
ATOM   12352 O O   . GLU E 2 204 ? 113.484 157.220 119.573 1.00 48.40  ? 179 GLU E O   1 
ATOM   12353 C CB  . GLU E 2 204 ? 113.731 159.899 117.855 1.00 49.96  ? 179 GLU E CB  1 
ATOM   12354 C CG  . GLU E 2 204 ? 112.911 159.579 116.611 1.00 59.77  ? 179 GLU E CG  1 
ATOM   12355 C CD  . GLU E 2 204 ? 113.724 159.660 115.333 1.00 56.68  ? 179 GLU E CD  1 
ATOM   12356 O OE1 . GLU E 2 204 ? 114.718 160.415 115.308 1.00 53.17  ? 179 GLU E OE1 1 
ATOM   12357 O OE2 . GLU E 2 204 ? 113.369 158.969 114.355 1.00 53.63  ? 179 GLU E OE2 1 
ATOM   12358 N N   . ARG E 2 205 ? 113.968 156.628 117.458 1.00 52.37  ? 180 ARG E N   1 
ATOM   12359 C CA  . ARG E 2 205 ? 113.263 155.356 117.557 1.00 50.27  ? 180 ARG E CA  1 
ATOM   12360 C C   . ARG E 2 205 ? 114.075 154.284 118.271 1.00 49.30  ? 180 ARG E C   1 
ATOM   12361 O O   . ARG E 2 205 ? 113.509 153.256 118.655 1.00 44.88  ? 180 ARG E O   1 
ATOM   12362 C CB  . ARG E 2 205 ? 112.873 154.858 116.163 1.00 51.21  ? 180 ARG E CB  1 
ATOM   12363 C CG  . ARG E 2 205 ? 112.185 155.902 115.298 1.00 54.30  ? 180 ARG E CG  1 
ATOM   12364 C CD  . ARG E 2 205 ? 111.675 155.291 114.002 1.00 61.91  ? 180 ARG E CD  1 
ATOM   12365 N NE  . ARG E 2 205 ? 111.137 156.298 113.095 1.00 73.52  ? 180 ARG E NE  1 
ATOM   12366 C CZ  . ARG E 2 205 ? 111.800 156.813 112.068 1.00 68.60  ? 180 ARG E CZ  1 
ATOM   12367 N NH1 . ARG E 2 205 ? 113.029 156.422 111.773 1.00 63.27  ? 180 ARG E NH1 1 
ATOM   12368 N NH2 . ARG E 2 205 ? 111.213 157.739 111.316 1.00 66.03  ? 180 ARG E NH2 1 
ATOM   12369 N N   . ILE E 2 206 ? 115.382 154.498 118.445 1.00 53.45  ? 181 ILE E N   1 
ATOM   12370 C CA  . ILE E 2 206 ? 116.240 153.489 119.051 1.00 50.33  ? 181 ILE E CA  1 
ATOM   12371 C C   . ILE E 2 206 ? 115.826 153.259 120.496 1.00 52.15  ? 181 ILE E C   1 
ATOM   12372 O O   . ILE E 2 206 ? 115.555 154.207 121.245 1.00 54.80  ? 181 ILE E O   1 
ATOM   12373 C CB  . ILE E 2 206 ? 117.712 153.928 118.968 1.00 49.51  ? 181 ILE E CB  1 
ATOM   12374 C CG1 . ILE E 2 206 ? 118.195 153.927 117.520 1.00 45.31  ? 181 ILE E CG1 1 
ATOM   12375 C CG2 . ILE E 2 206 ? 118.595 153.026 119.814 1.00 38.63  ? 181 ILE E CG2 1 
ATOM   12376 C CD1 . ILE E 2 206 ? 119.500 154.657 117.337 1.00 44.41  ? 181 ILE E CD1 1 
ATOM   12377 N N   . GLU E 2 207 ? 115.772 151.992 120.898 1.00 51.19  ? 182 GLU E N   1 
ATOM   12378 C CA  . GLU E 2 207 ? 115.521 151.628 122.286 1.00 50.28  ? 182 GLU E CA  1 
ATOM   12379 C C   . GLU E 2 207 ? 116.652 150.731 122.765 1.00 47.13  ? 182 GLU E C   1 
ATOM   12380 O O   . GLU E 2 207 ? 116.924 149.691 122.156 1.00 46.34  ? 182 GLU E O   1 
ATOM   12381 C CB  . GLU E 2 207 ? 114.176 150.915 122.432 1.00 50.20  ? 182 GLU E CB  1 
ATOM   12382 C CG  . GLU E 2 207 ? 112.973 151.757 122.041 1.00 53.62  ? 182 GLU E CG  1 
ATOM   12383 C CD  . GLU E 2 207 ? 111.669 150.990 122.150 1.00 59.44  ? 182 GLU E CD  1 
ATOM   12384 O OE1 . GLU E 2 207 ? 111.651 149.936 122.821 1.00 54.71  ? 182 GLU E OE1 1 
ATOM   12385 O OE2 . GLU E 2 207 ? 110.662 151.438 121.561 1.00 71.63  ? 182 GLU E OE2 1 
ATOM   12386 N N   . LEU E 2 208 ? 117.310 151.139 123.850 1.00 40.53  ? 183 LEU E N   1 
ATOM   12387 C CA  . LEU E 2 208 ? 118.377 150.370 124.462 1.00 34.94  ? 183 LEU E CA  1 
ATOM   12388 C C   . LEU E 2 208 ? 117.964 149.882 125.843 1.00 32.29  ? 183 LEU E C   1 
ATOM   12389 O O   . LEU E 2 208 ? 117.385 150.648 126.621 1.00 25.57  ? 183 LEU E O   1 
ATOM   12390 C CB  . LEU E 2 208 ? 119.664 151.192 124.585 1.00 29.34  ? 183 LEU E CB  1 
ATOM   12391 C CG  . LEU E 2 208 ? 120.365 151.533 123.274 1.00 25.86  ? 183 LEU E CG  1 
ATOM   12392 C CD1 . LEU E 2 208 ? 121.478 152.529 123.513 1.00 25.02  ? 183 LEU E CD1 1 
ATOM   12393 C CD2 . LEU E 2 208 ? 120.907 150.266 122.653 1.00 27.21  ? 183 LEU E CD2 1 
ATOM   12394 N N   . PRO E 2 209 ? 118.228 148.615 126.171 1.00 30.01  ? 184 PRO E N   1 
ATOM   12395 C CA  . PRO E 2 209 ? 117.793 148.096 127.474 1.00 25.46  ? 184 PRO E CA  1 
ATOM   12396 C C   . PRO E 2 209 ? 118.479 148.768 128.647 1.00 25.44  ? 184 PRO E C   1 
ATOM   12397 O O   . PRO E 2 209 ? 117.979 148.666 129.773 1.00 26.84  ? 184 PRO E O   1 
ATOM   12398 C CB  . PRO E 2 209 ? 118.151 146.607 127.397 1.00 26.98  ? 184 PRO E CB  1 
ATOM   12399 C CG  . PRO E 2 209 ? 119.267 146.545 126.416 1.00 27.51  ? 184 PRO E CG  1 
ATOM   12400 C CD  . PRO E 2 209 ? 118.993 147.619 125.403 1.00 26.55  ? 184 PRO E CD  1 
ATOM   12401 N N   . GLN E 2 210 ? 119.602 149.454 128.422 1.00 28.07  ? 185 GLN E N   1 
ATOM   12402 C CA  . GLN E 2 210 ? 120.409 149.982 129.510 1.00 25.36  ? 185 GLN E CA  1 
ATOM   12403 C C   . GLN E 2 210 ? 120.809 151.443 129.334 1.00 23.04  ? 185 GLN E C   1 
ATOM   12404 O O   . GLN E 2 210 ? 121.310 152.043 130.291 1.00 23.82  ? 185 GLN E O   1 
ATOM   12405 C CB  . GLN E 2 210 ? 121.672 149.119 129.685 1.00 22.52  ? 185 GLN E CB  1 
ATOM   12406 C CG  . GLN E 2 210 ? 122.504 149.400 130.924 1.00 26.24  ? 185 GLN E CG  1 
ATOM   12407 C CD  . GLN E 2 210 ? 123.295 148.190 131.371 1.00 31.00  ? 185 GLN E CD  1 
ATOM   12408 O OE1 . GLN E 2 210 ? 123.685 148.082 132.534 1.00 24.86  ? 185 GLN E OE1 1 
ATOM   12409 N NE2 . GLN E 2 210 ? 123.540 147.269 130.445 1.00 43.50  ? 185 GLN E NE2 1 
ATOM   12410 N N   . PHE E 2 211 ? 120.565 152.048 128.175 1.00 22.45  ? 186 PHE E N   1 
ATOM   12411 C CA  . PHE E 2 211 ? 120.945 153.431 127.932 1.00 21.05  ? 186 PHE E CA  1 
ATOM   12412 C C   . PHE E 2 211 ? 119.780 154.189 127.312 1.00 21.57  ? 186 PHE E C   1 
ATOM   12413 O O   . PHE E 2 211 ? 118.804 153.603 126.837 1.00 25.20  ? 186 PHE E O   1 
ATOM   12414 C CB  . PHE E 2 211 ? 122.168 153.523 127.007 1.00 21.50  ? 186 PHE E CB  1 
ATOM   12415 C CG  . PHE E 2 211 ? 123.435 152.991 127.611 1.00 24.79  ? 186 PHE E CG  1 
ATOM   12416 C CD1 . PHE E 2 211 ? 124.231 153.796 128.405 1.00 24.89  ? 186 PHE E CD1 1 
ATOM   12417 C CD2 . PHE E 2 211 ? 123.838 151.690 127.370 1.00 23.38  ? 186 PHE E CD2 1 
ATOM   12418 C CE1 . PHE E 2 211 ? 125.400 153.311 128.954 1.00 24.20  ? 186 PHE E CE1 1 
ATOM   12419 C CE2 . PHE E 2 211 ? 125.006 151.200 127.916 1.00 23.50  ? 186 PHE E CE2 1 
ATOM   12420 C CZ  . PHE E 2 211 ? 125.787 152.011 128.710 1.00 23.99  ? 186 PHE E CZ  1 
ATOM   12421 N N   . SER E 2 212 ? 119.896 155.514 127.324 1.00 18.60  ? 187 SER E N   1 
ATOM   12422 C CA  . SER E 2 212 ? 119.014 156.397 126.576 1.00 20.35  ? 187 SER E CA  1 
ATOM   12423 C C   . SER E 2 212 ? 119.865 157.321 125.721 1.00 23.33  ? 187 SER E C   1 
ATOM   12424 O O   . SER E 2 212 ? 120.873 157.853 126.191 1.00 26.26  ? 187 SER E O   1 
ATOM   12425 C CB  . SER E 2 212 ? 118.120 157.219 127.507 1.00 21.91  ? 187 SER E CB  1 
ATOM   12426 O OG  . SER E 2 212 ? 118.879 158.182 128.215 1.00 23.02  ? 187 SER E OG  1 
ATOM   12427 N N   . ILE E 2 213 ? 119.458 157.516 124.468 1.00 23.39  ? 188 ILE E N   1 
ATOM   12428 C CA  . ILE E 2 213 ? 120.218 158.363 123.550 1.00 23.87  ? 188 ILE E CA  1 
ATOM   12429 C C   . ILE E 2 213 ? 119.894 159.810 123.910 1.00 24.03  ? 188 ILE E C   1 
ATOM   12430 O O   . ILE E 2 213 ? 118.854 160.337 123.513 1.00 26.16  ? 188 ILE E O   1 
ATOM   12431 C CB  . ILE E 2 213 ? 119.887 158.070 122.086 1.00 25.92  ? 188 ILE E CB  1 
ATOM   12432 C CG1 . ILE E 2 213 ? 119.855 156.567 121.810 1.00 25.17  ? 188 ILE E CG1 1 
ATOM   12433 C CG2 . ILE E 2 213 ? 120.928 158.713 121.196 1.00 25.97  ? 188 ILE E CG2 1 
ATOM   12434 C CD1 . ILE E 2 213 ? 121.104 155.848 122.179 1.00 27.16  ? 188 ILE E CD1 1 
ATOM   12435 N N   . VAL E 2 214 ? 120.780 160.462 124.665 1.00 21.24  ? 189 VAL E N   1 
ATOM   12436 C CA  . VAL E 2 214 ? 120.520 161.844 125.054 1.00 22.80  ? 189 VAL E CA  1 
ATOM   12437 C C   . VAL E 2 214 ? 120.645 162.775 123.855 1.00 28.63  ? 189 VAL E C   1 
ATOM   12438 O O   . VAL E 2 214 ? 119.831 163.687 123.672 1.00 39.05  ? 189 VAL E O   1 
ATOM   12439 C CB  . VAL E 2 214 ? 121.466 162.262 126.194 1.00 24.66  ? 189 VAL E CB  1 
ATOM   12440 C CG1 . VAL E 2 214 ? 121.237 163.715 126.570 1.00 25.69  ? 189 VAL E CG1 1 
ATOM   12441 C CG2 . VAL E 2 214 ? 121.263 161.362 127.397 1.00 26.83  ? 189 VAL E CG2 1 
ATOM   12442 N N   . GLU E 2 215 ? 121.654 162.556 123.016 1.00 25.52  ? 190 GLU E N   1 
ATOM   12443 C CA  . GLU E 2 215 ? 121.955 163.475 121.928 1.00 27.95  ? 190 GLU E CA  1 
ATOM   12444 C C   . GLU E 2 215 ? 122.816 162.739 120.911 1.00 29.45  ? 190 GLU E C   1 
ATOM   12445 O O   . GLU E 2 215 ? 123.413 161.704 121.213 1.00 29.93  ? 190 GLU E O   1 
ATOM   12446 C CB  . GLU E 2 215 ? 122.644 164.746 122.451 1.00 28.39  ? 190 GLU E CB  1 
ATOM   12447 C CG  . GLU E 2 215 ? 122.956 165.805 121.396 1.00 35.33  ? 190 GLU E CG  1 
ATOM   12448 C CD  . GLU E 2 215 ? 123.679 167.010 121.963 1.00 45.47  ? 190 GLU E CD  1 
ATOM   12449 O OE1 . GLU E 2 215 ? 124.031 166.989 123.160 1.00 49.12  ? 190 GLU E OE1 1 
ATOM   12450 O OE2 . GLU E 2 215 ? 123.893 167.984 121.210 1.00 44.95  ? 190 GLU E OE2 1 
ATOM   12451 N N   . HIS E 2 216 ? 122.869 163.282 119.697 1.00 29.49  ? 191 HIS E N   1 
ATOM   12452 C CA  . HIS E 2 216 ? 123.828 162.835 118.699 1.00 24.95  ? 191 HIS E CA  1 
ATOM   12453 C C   . HIS E 2 216 ? 124.317 164.043 117.914 1.00 23.77  ? 191 HIS E C   1 
ATOM   12454 O O   . HIS E 2 216 ? 123.590 165.023 117.735 1.00 27.05  ? 191 HIS E O   1 
ATOM   12455 C CB  . HIS E 2 216 ? 123.224 161.775 117.763 1.00 20.80  ? 191 HIS E CB  1 
ATOM   12456 C CG  . HIS E 2 216 ? 122.292 162.330 116.731 1.00 20.52  ? 191 HIS E CG  1 
ATOM   12457 N ND1 . HIS E 2 216 ? 120.925 162.340 116.894 1.00 24.79  ? 191 HIS E ND1 1 
ATOM   12458 C CD2 . HIS E 2 216 ? 122.530 162.877 115.516 1.00 21.64  ? 191 HIS E CD2 1 
ATOM   12459 C CE1 . HIS E 2 216 ? 120.360 162.878 115.828 1.00 23.89  ? 191 HIS E CE1 1 
ATOM   12460 N NE2 . HIS E 2 216 ? 121.312 163.214 114.977 1.00 21.68  ? 191 HIS E NE2 1 
ATOM   12461 N N   . ARG E 2 217 ? 125.562 163.961 117.450 1.00 20.97  ? 192 ARG E N   1 
ATOM   12462 C CA  . ARG E 2 217 ? 126.216 165.052 116.742 1.00 20.25  ? 192 ARG E CA  1 
ATOM   12463 C C   . ARG E 2 217 ? 126.891 164.539 115.480 1.00 22.17  ? 192 ARG E C   1 
ATOM   12464 O O   . ARG E 2 217 ? 127.313 163.383 115.403 1.00 25.57  ? 192 ARG E O   1 
ATOM   12465 C CB  . ARG E 2 217 ? 127.258 165.760 117.616 1.00 22.29  ? 192 ARG E CB  1 
ATOM   12466 C CG  . ARG E 2 217 ? 126.704 166.398 118.874 1.00 30.55  ? 192 ARG E CG  1 
ATOM   12467 C CD  . ARG E 2 217 ? 127.821 167.018 119.693 1.00 37.42  ? 192 ARG E CD  1 
ATOM   12468 N NE  . ARG E 2 217 ? 127.366 167.481 120.997 1.00 42.25  ? 192 ARG E NE  1 
ATOM   12469 C CZ  . ARG E 2 217 ? 128.175 167.873 121.972 1.00 41.26  ? 192 ARG E CZ  1 
ATOM   12470 N NH1 . ARG E 2 217 ? 129.489 167.872 121.822 1.00 37.96  ? 192 ARG E NH1 1 
ATOM   12471 N NH2 . ARG E 2 217 ? 127.652 168.277 123.126 1.00 43.46  ? 192 ARG E NH2 1 
ATOM   12472 N N   . LEU E 2 218 ? 126.984 165.420 114.490 1.00 24.21  ? 193 LEU E N   1 
ATOM   12473 C CA  . LEU E 2 218 ? 127.714 165.160 113.258 1.00 23.04  ? 193 LEU E CA  1 
ATOM   12474 C C   . LEU E 2 218 ? 128.901 166.107 113.184 1.00 24.62  ? 193 LEU E C   1 
ATOM   12475 O O   . LEU E 2 218 ? 128.735 167.327 113.284 1.00 27.91  ? 193 LEU E O   1 
ATOM   12476 C CB  . LEU E 2 218 ? 126.806 165.348 112.043 1.00 23.91  ? 193 LEU E CB  1 
ATOM   12477 C CG  . LEU E 2 218 ? 125.564 164.463 112.037 1.00 24.81  ? 193 LEU E CG  1 
ATOM   12478 C CD1 . LEU E 2 218 ? 124.759 164.670 110.775 1.00 31.91  ? 193 LEU E CD1 1 
ATOM   12479 C CD2 . LEU E 2 218 ? 125.978 163.020 112.166 1.00 21.72  ? 193 LEU E CD2 1 
ATOM   12480 N N   . VAL E 2 219 ? 130.095 165.544 113.015 1.00 22.61  ? 194 VAL E N   1 
ATOM   12481 C CA  . VAL E 2 219 ? 131.323 166.320 112.911 1.00 19.78  ? 194 VAL E CA  1 
ATOM   12482 C C   . VAL E 2 219 ? 132.005 165.982 111.594 1.00 20.48  ? 194 VAL E C   1 
ATOM   12483 O O   . VAL E 2 219 ? 131.883 164.867 111.077 1.00 25.63  ? 194 VAL E O   1 
ATOM   12484 C CB  . VAL E 2 219 ? 132.255 166.037 114.115 1.00 24.58  ? 194 VAL E CB  1 
ATOM   12485 C CG1 . VAL E 2 219 ? 133.551 166.831 114.022 1.00 33.60  ? 194 VAL E CG1 1 
ATOM   12486 C CG2 . VAL E 2 219 ? 131.538 166.325 115.427 1.00 29.41  ? 194 VAL E CG2 1 
ATOM   12487 N N   . SER E 2 220 ? 132.730 166.958 111.052 1.00 21.35  ? 195 SER E N   1 
ATOM   12488 C CA  . SER E 2 220 ? 133.508 166.790 109.833 1.00 25.59  ? 195 SER E CA  1 
ATOM   12489 C C   . SER E 2 220 ? 134.860 167.457 110.025 1.00 34.19  ? 195 SER E C   1 
ATOM   12490 O O   . SER E 2 220 ? 134.924 168.609 110.463 1.00 46.81  ? 195 SER E O   1 
ATOM   12491 C CB  . SER E 2 220 ? 132.789 167.390 108.621 1.00 27.35  ? 195 SER E CB  1 
ATOM   12492 O OG  . SER E 2 220 ? 133.508 167.129 107.428 1.00 29.48  ? 195 SER E OG  1 
ATOM   12493 N N   . ARG E 2 221 ? 135.932 166.742 109.698 1.00 32.14  ? 196 ARG E N   1 
ATOM   12494 C CA  . ARG E 2 221 ? 137.277 167.248 109.940 1.00 40.48  ? 196 ARG E CA  1 
ATOM   12495 C C   . ARG E 2 221 ? 138.256 166.473 109.068 1.00 40.86  ? 196 ARG E C   1 
ATOM   12496 O O   . ARG E 2 221 ? 137.870 165.587 108.300 1.00 44.13  ? 196 ARG E O   1 
ATOM   12497 C CB  . ARG E 2 221 ? 137.632 167.140 111.426 1.00 44.43  ? 196 ARG E CB  1 
ATOM   12498 C CG  . ARG E 2 221 ? 137.507 165.734 111.987 1.00 40.26  ? 196 ARG E CG  1 
ATOM   12499 C CD  . ARG E 2 221 ? 137.781 165.701 113.482 1.00 41.36  ? 196 ARG E CD  1 
ATOM   12500 N NE  . ARG E 2 221 ? 139.120 166.167 113.817 1.00 49.92  ? 196 ARG E NE  1 
ATOM   12501 C CZ  . ARG E 2 221 ? 140.143 165.369 114.090 1.00 56.28  ? 196 ARG E CZ  1 
ATOM   12502 N NH1 . ARG E 2 221 ? 140.011 164.053 114.092 1.00 54.48  ? 196 ARG E NH1 1 
ATOM   12503 N NH2 . ARG E 2 221 ? 141.326 165.905 114.376 1.00 60.82  ? 196 ARG E NH2 1 
ATOM   12504 N N   . ASN E 2 222 ? 139.535 166.821 109.189 1.00 40.40  ? 197 ASN E N   1 
ATOM   12505 C CA  . ASN E 2 222 ? 140.613 166.149 108.480 1.00 41.68  ? 197 ASN E CA  1 
ATOM   12506 C C   . ASN E 2 222 ? 141.619 165.586 109.473 1.00 45.65  ? 197 ASN E C   1 
ATOM   12507 O O   . ASN E 2 222 ? 141.963 166.244 110.460 1.00 46.97  ? 197 ASN E O   1 
ATOM   12508 C CB  . ASN E 2 222 ? 141.311 167.110 107.516 1.00 38.59  ? 197 ASN E CB  1 
ATOM   12509 C CG  . ASN E 2 222 ? 140.447 167.462 106.324 1.00 37.16  ? 197 ASN E CG  1 
ATOM   12510 O OD1 . ASN E 2 222 ? 139.762 166.606 105.766 1.00 43.86  ? 197 ASN E OD1 1 
ATOM   12511 N ND2 . ASN E 2 222 ? 140.471 168.729 105.930 1.00 31.69  ? 197 ASN E ND2 1 
ATOM   12512 N N   . VAL E 2 223 ? 142.094 164.372 109.209 1.00 49.40  ? 198 VAL E N   1 
ATOM   12513 C CA  . VAL E 2 223 ? 143.100 163.721 110.040 1.00 52.60  ? 198 VAL E CA  1 
ATOM   12514 C C   . VAL E 2 223 ? 144.365 163.547 109.210 1.00 56.13  ? 198 VAL E C   1 
ATOM   12515 O O   . VAL E 2 223 ? 144.303 163.097 108.060 1.00 56.98  ? 198 VAL E O   1 
ATOM   12516 C CB  . VAL E 2 223 ? 142.602 162.370 110.584 1.00 48.77  ? 198 VAL E CB  1 
ATOM   12517 C CG1 . VAL E 2 223 ? 143.618 161.783 111.547 1.00 51.54  ? 198 VAL E CG1 1 
ATOM   12518 C CG2 . VAL E 2 223 ? 141.258 162.544 111.267 1.00 45.29  ? 198 VAL E CG2 1 
ATOM   12519 N N   . VAL E 2 224 ? 145.505 163.901 109.796 1.00 60.11  ? 199 VAL E N   1 
ATOM   12520 C CA  . VAL E 2 224 ? 146.799 163.903 109.122 1.00 63.90  ? 199 VAL E CA  1 
ATOM   12521 C C   . VAL E 2 224 ? 147.628 162.734 109.636 1.00 66.49  ? 199 VAL E C   1 
ATOM   12522 O O   . VAL E 2 224 ? 147.820 162.589 110.849 1.00 62.85  ? 199 VAL E O   1 
ATOM   12523 C CB  . VAL E 2 224 ? 147.542 165.234 109.328 1.00 65.13  ? 199 VAL E CB  1 
ATOM   12524 C CG1 . VAL E 2 224 ? 148.882 165.210 108.608 1.00 66.84  ? 199 VAL E CG1 1 
ATOM   12525 C CG2 . VAL E 2 224 ? 146.692 166.396 108.837 1.00 59.53  ? 199 VAL E CG2 1 
ATOM   12526 N N   . PHE E 2 225 ? 148.112 161.901 108.719 1.00 69.89  ? 200 PHE E N   1 
ATOM   12527 C CA  . PHE E 2 225 ? 148.947 160.758 109.065 1.00 74.68  ? 200 PHE E CA  1 
ATOM   12528 C C   . PHE E 2 225 ? 150.334 160.933 108.443 1.00 76.42  ? 200 PHE E C   1 
ATOM   12529 O O   . PHE E 2 225 ? 150.663 161.983 107.882 1.00 72.77  ? 200 PHE E O   1 
ATOM   12530 C CB  . PHE E 2 225 ? 148.319 159.442 108.596 1.00 70.44  ? 200 PHE E CB  1 
ATOM   12531 C CG  . PHE E 2 225 ? 146.995 159.129 109.229 1.00 68.60  ? 200 PHE E CG  1 
ATOM   12532 C CD1 . PHE E 2 225 ? 145.824 159.665 108.722 1.00 64.92  ? 200 PHE E CD1 1 
ATOM   12533 C CD2 . PHE E 2 225 ? 146.922 158.290 110.328 1.00 68.47  ? 200 PHE E CD2 1 
ATOM   12534 C CE1 . PHE E 2 225 ? 144.604 159.366 109.298 1.00 60.04  ? 200 PHE E CE1 1 
ATOM   12535 C CE2 . PHE E 2 225 ? 145.706 157.992 110.913 1.00 63.23  ? 200 PHE E CE2 1 
ATOM   12536 C CZ  . PHE E 2 225 ? 144.545 158.532 110.397 1.00 56.58  ? 200 PHE E CZ  1 
ATOM   12537 N N   . ALA E 2 226 ? 151.150 159.882 108.551 1.00 78.74  ? 201 ALA E N   1 
ATOM   12538 C CA  . ALA E 2 226 ? 152.448 159.870 107.885 1.00 81.13  ? 201 ALA E CA  1 
ATOM   12539 C C   . ALA E 2 226 ? 152.308 159.832 106.369 1.00 82.61  ? 201 ALA E C   1 
ATOM   12540 O O   . ALA E 2 226 ? 153.161 160.374 105.657 1.00 80.68  ? 201 ALA E O   1 
ATOM   12541 C CB  . ALA E 2 226 ? 153.276 158.680 108.369 1.00 77.56  ? 201 ALA E CB  1 
ATOM   12542 N N   . THR E 2 227 ? 151.250 159.208 105.862 1.00 81.59  ? 202 THR E N   1 
ATOM   12543 C CA  . THR E 2 227 ? 151.042 159.057 104.428 1.00 79.07  ? 202 THR E CA  1 
ATOM   12544 C C   . THR E 2 227 ? 150.205 160.178 103.827 1.00 79.41  ? 202 THR E C   1 
ATOM   12545 O O   . THR E 2 227 ? 149.910 160.135 102.628 1.00 81.59  ? 202 THR E O   1 
ATOM   12546 C CB  . THR E 2 227 ? 150.380 157.707 104.128 1.00 79.50  ? 202 THR E CB  1 
ATOM   12547 O OG1 . THR E 2 227 ? 149.158 157.595 104.867 1.00 78.34  ? 202 THR E OG1 1 
ATOM   12548 C CG2 . THR E 2 227 ? 151.306 156.562 104.509 1.00 76.75  ? 202 THR E CG2 1 
ATOM   12549 N N   . GLY E 2 228 ? 149.821 161.171 104.616 1.00 74.60  ? 203 GLY E N   1 
ATOM   12550 C CA  . GLY E 2 228 ? 149.080 162.315 104.130 1.00 67.91  ? 203 GLY E CA  1 
ATOM   12551 C C   . GLY E 2 228 ? 147.769 162.492 104.870 1.00 65.76  ? 203 GLY E C   1 
ATOM   12552 O O   . GLY E 2 228 ? 147.388 161.696 105.726 1.00 65.26  ? 203 GLY E O   1 
ATOM   12553 N N   . ALA E 2 229 ? 147.091 163.586 104.537 1.00 65.93  ? 204 ALA E N   1 
ATOM   12554 C CA  . ALA E 2 229 ? 145.822 163.910 105.167 1.00 63.08  ? 204 ALA E CA  1 
ATOM   12555 C C   . ALA E 2 229 ? 144.688 163.106 104.543 1.00 55.31  ? 204 ALA E C   1 
ATOM   12556 O O   . ALA E 2 229 ? 144.705 162.787 103.351 1.00 53.46  ? 204 ALA E O   1 
ATOM   12557 C CB  . ALA E 2 229 ? 145.529 165.406 105.047 1.00 56.81  ? 204 ALA E CB  1 
ATOM   12558 N N   . TYR E 2 230 ? 143.696 162.773 105.367 1.00 52.95  ? 205 TYR E N   1 
ATOM   12559 C CA  . TYR E 2 230 ? 142.570 161.956 104.950 1.00 47.79  ? 205 TYR E CA  1 
ATOM   12560 C C   . TYR E 2 230 ? 141.269 162.601 105.406 1.00 45.61  ? 205 TYR E C   1 
ATOM   12561 O O   . TYR E 2 230 ? 141.219 163.209 106.482 1.00 42.59  ? 205 TYR E O   1 
ATOM   12562 C CB  . TYR E 2 230 ? 142.663 160.530 105.517 1.00 45.55  ? 205 TYR E CB  1 
ATOM   12563 C CG  . TYR E 2 230 ? 143.739 159.674 104.885 1.00 48.91  ? 205 TYR E CG  1 
ATOM   12564 C CD1 . TYR E 2 230 ? 145.068 159.811 105.254 1.00 56.31  ? 205 TYR E CD1 1 
ATOM   12565 C CD2 . TYR E 2 230 ? 143.422 158.728 103.920 1.00 46.25  ? 205 TYR E CD2 1 
ATOM   12566 C CE1 . TYR E 2 230 ? 146.054 159.031 104.678 1.00 60.51  ? 205 TYR E CE1 1 
ATOM   12567 C CE2 . TYR E 2 230 ? 144.399 157.943 103.340 1.00 47.81  ? 205 TYR E CE2 1 
ATOM   12568 C CZ  . TYR E 2 230 ? 145.714 158.099 103.723 1.00 55.86  ? 205 TYR E CZ  1 
ATOM   12569 O OH  . TYR E 2 230 ? 146.694 157.321 103.151 1.00 49.34  ? 205 TYR E OH  1 
ATOM   12570 N N   . PRO E 2 231 ? 140.202 162.484 104.618 1.00 42.55  ? 206 PRO E N   1 
ATOM   12571 C CA  . PRO E 2 231 ? 138.914 163.039 105.040 1.00 34.65  ? 206 PRO E CA  1 
ATOM   12572 C C   . PRO E 2 231 ? 138.276 162.174 106.113 1.00 32.93  ? 206 PRO E C   1 
ATOM   12573 O O   . PRO E 2 231 ? 138.355 160.944 106.081 1.00 37.31  ? 206 PRO E O   1 
ATOM   12574 C CB  . PRO E 2 231 ? 138.090 163.030 103.748 1.00 31.79  ? 206 PRO E CB  1 
ATOM   12575 C CG  . PRO E 2 231 ? 138.630 161.867 102.991 1.00 36.61  ? 206 PRO E CG  1 
ATOM   12576 C CD  . PRO E 2 231 ? 140.105 161.793 103.319 1.00 41.89  ? 206 PRO E CD  1 
ATOM   12577 N N   . ARG E 2 232 ? 137.632 162.834 107.071 1.00 30.32  ? 207 ARG E N   1 
ATOM   12578 C CA  . ARG E 2 232 ? 137.010 162.156 108.199 1.00 27.88  ? 207 ARG E CA  1 
ATOM   12579 C C   . ARG E 2 232 ? 135.598 162.679 108.399 1.00 25.01  ? 207 ARG E C   1 
ATOM   12580 O O   . ARG E 2 232 ? 135.369 163.892 108.373 1.00 29.67  ? 207 ARG E O   1 
ATOM   12581 C CB  . ARG E 2 232 ? 137.826 162.371 109.478 1.00 29.21  ? 207 ARG E CB  1 
ATOM   12582 C CG  . ARG E 2 232 ? 137.166 161.843 110.740 1.00 25.13  ? 207 ARG E CG  1 
ATOM   12583 C CD  . ARG E 2 232 ? 137.188 160.333 110.802 1.00 29.47  ? 207 ARG E CD  1 
ATOM   12584 N NE  . ARG E 2 232 ? 138.549 159.816 110.854 1.00 36.05  ? 207 ARG E NE  1 
ATOM   12585 C CZ  . ARG E 2 232 ? 139.258 159.696 111.968 1.00 36.37  ? 207 ARG E CZ  1 
ATOM   12586 N NH1 . ARG E 2 232 ? 138.759 160.036 113.145 1.00 30.63  ? 207 ARG E NH1 1 
ATOM   12587 N NH2 . ARG E 2 232 ? 140.498 159.218 111.900 1.00 38.62  ? 207 ARG E NH2 1 
ATOM   12588 N N   . LEU E 2 233 ? 134.660 161.758 108.597 1.00 20.59  ? 208 LEU E N   1 
ATOM   12589 C CA  . LEU E 2 233 ? 133.327 162.062 109.092 1.00 20.02  ? 208 LEU E CA  1 
ATOM   12590 C C   . LEU E 2 233 ? 133.113 161.295 110.384 1.00 20.11  ? 208 LEU E C   1 
ATOM   12591 O O   . LEU E 2 233 ? 133.376 160.090 110.444 1.00 25.22  ? 208 LEU E O   1 
ATOM   12592 C CB  . LEU E 2 233 ? 132.239 161.696 108.082 1.00 20.46  ? 208 LEU E CB  1 
ATOM   12593 C CG  . LEU E 2 233 ? 132.157 162.536 106.812 1.00 23.40  ? 208 LEU E CG  1 
ATOM   12594 C CD1 . LEU E 2 233 ? 130.944 162.130 105.999 1.00 28.71  ? 208 LEU E CD1 1 
ATOM   12595 C CD2 . LEU E 2 233 ? 132.110 164.016 107.144 1.00 20.84  ? 208 LEU E CD2 1 
ATOM   12596 N N   . SER E 2 234 ? 132.641 161.987 111.411 1.00 15.24  ? 209 SER E N   1 
ATOM   12597 C CA  . SER E 2 234 ? 132.393 161.375 112.704 1.00 14.19  ? 209 SER E CA  1 
ATOM   12598 C C   . SER E 2 234 ? 130.914 161.489 113.026 1.00 16.25  ? 209 SER E C   1 
ATOM   12599 O O   . SER E 2 234 ? 130.312 162.553 112.850 1.00 21.38  ? 209 SER E O   1 
ATOM   12600 C CB  . SER E 2 234 ? 133.229 162.038 113.801 1.00 18.45  ? 209 SER E CB  1 
ATOM   12601 O OG  . SER E 2 234 ? 134.578 162.188 113.396 1.00 26.09  ? 209 SER E OG  1 
ATOM   12602 N N   . LEU E 2 235 ? 130.340 160.390 113.497 1.00 18.86  ? 210 LEU E N   1 
ATOM   12603 C CA  . LEU E 2 235 ? 129.022 160.366 114.110 1.00 20.43  ? 210 LEU E CA  1 
ATOM   12604 C C   . LEU E 2 235 ? 129.189 159.897 115.542 1.00 20.59  ? 210 LEU E C   1 
ATOM   12605 O O   . LEU E 2 235 ? 129.800 158.854 115.786 1.00 26.63  ? 210 LEU E O   1 
ATOM   12606 C CB  . LEU E 2 235 ? 128.071 159.436 113.354 1.00 19.97  ? 210 LEU E CB  1 
ATOM   12607 C CG  . LEU E 2 235 ? 126.777 159.047 114.073 1.00 19.14  ? 210 LEU E CG  1 
ATOM   12608 C CD1 . LEU E 2 235 ? 125.901 160.250 114.347 1.00 22.30  ? 210 LEU E CD1 1 
ATOM   12609 C CD2 . LEU E 2 235 ? 126.019 158.006 113.266 1.00 18.19  ? 210 LEU E CD2 1 
ATOM   12610 N N   . SER E 2 236 ? 128.643 160.655 116.481 1.00 15.98  ? 211 SER E N   1 
ATOM   12611 C CA  . SER E 2 236 ? 128.803 160.340 117.888 1.00 19.19  ? 211 SER E CA  1 
ATOM   12612 C C   . SER E 2 236 ? 127.458 160.423 118.585 1.00 21.29  ? 211 SER E C   1 
ATOM   12613 O O   . SER E 2 236 ? 126.607 161.246 118.242 1.00 23.87  ? 211 SER E O   1 
ATOM   12614 C CB  . SER E 2 236 ? 129.799 161.287 118.566 1.00 23.51  ? 211 SER E CB  1 
ATOM   12615 O OG  . SER E 2 236 ? 129.408 162.638 118.406 1.00 34.76  ? 211 SER E OG  1 
ATOM   12616 N N   . PHE E 2 237 ? 127.289 159.561 119.578 1.00 23.42  ? 212 PHE E N   1 
ATOM   12617 C CA  . PHE E 2 237 ? 126.116 159.543 120.431 1.00 23.06  ? 212 PHE E CA  1 
ATOM   12618 C C   . PHE E 2 237 ? 126.561 159.795 121.861 1.00 21.99  ? 212 PHE E C   1 
ATOM   12619 O O   . PHE E 2 237 ? 127.684 159.457 122.242 1.00 23.90  ? 212 PHE E O   1 
ATOM   12620 C CB  . PHE E 2 237 ? 125.376 158.203 120.347 1.00 24.13  ? 212 PHE E CB  1 
ATOM   12621 C CG  . PHE E 2 237 ? 125.132 157.729 118.944 1.00 24.86  ? 212 PHE E CG  1 
ATOM   12622 C CD1 . PHE E 2 237 ? 124.014 158.142 118.242 1.00 26.70  ? 212 PHE E CD1 1 
ATOM   12623 C CD2 . PHE E 2 237 ? 126.017 156.859 118.331 1.00 22.08  ? 212 PHE E CD2 1 
ATOM   12624 C CE1 . PHE E 2 237 ? 123.789 157.702 116.953 1.00 27.28  ? 212 PHE E CE1 1 
ATOM   12625 C CE2 . PHE E 2 237 ? 125.798 156.418 117.044 1.00 22.30  ? 212 PHE E CE2 1 
ATOM   12626 C CZ  . PHE E 2 237 ? 124.683 156.840 116.355 1.00 25.63  ? 212 PHE E CZ  1 
ATOM   12627 N N   . ARG E 2 238 ? 125.678 160.382 122.654 1.00 20.18  ? 213 ARG E N   1 
ATOM   12628 C CA  . ARG E 2 238 ? 125.897 160.484 124.087 1.00 20.50  ? 213 ARG E CA  1 
ATOM   12629 C C   . ARG E 2 238 ? 124.900 159.561 124.766 1.00 18.37  ? 213 ARG E C   1 
ATOM   12630 O O   . ARG E 2 238 ? 123.690 159.681 124.552 1.00 23.24  ? 213 ARG E O   1 
ATOM   12631 C CB  . ARG E 2 238 ? 125.734 161.922 124.577 1.00 28.22  ? 213 ARG E CB  1 
ATOM   12632 C CG  . ARG E 2 238 ? 126.224 162.134 125.997 1.00 32.48  ? 213 ARG E CG  1 
ATOM   12633 C CD  . ARG E 2 238 ? 126.633 163.575 126.244 1.00 40.08  ? 213 ARG E CD  1 
ATOM   12634 N NE  . ARG E 2 238 ? 125.480 164.461 126.355 1.00 47.11  ? 213 ARG E NE  1 
ATOM   12635 C CZ  . ARG E 2 238 ? 125.078 165.293 125.404 1.00 45.48  ? 213 ARG E CZ  1 
ATOM   12636 N NH1 . ARG E 2 238 ? 125.715 165.381 124.248 1.00 41.73  ? 213 ARG E NH1 1 
ATOM   12637 N NH2 . ARG E 2 238 ? 124.010 166.056 125.618 1.00 41.85  ? 213 ARG E NH2 1 
ATOM   12638 N N   . LEU E 2 239 ? 125.412 158.646 125.579 1.00 16.38  ? 214 LEU E N   1 
ATOM   12639 C CA  . LEU E 2 239 ? 124.607 157.626 126.229 1.00 17.91  ? 214 LEU E CA  1 
ATOM   12640 C C   . LEU E 2 239 ? 124.596 157.886 127.725 1.00 20.14  ? 214 LEU E C   1 
ATOM   12641 O O   . LEU E 2 239 ? 125.657 158.017 128.342 1.00 25.81  ? 214 LEU E O   1 
ATOM   12642 C CB  . LEU E 2 239 ? 125.170 156.232 125.946 1.00 17.27  ? 214 LEU E CB  1 
ATOM   12643 C CG  . LEU E 2 239 ? 125.454 155.893 124.483 1.00 17.70  ? 214 LEU E CG  1 
ATOM   12644 C CD1 . LEU E 2 239 ? 125.950 154.465 124.341 1.00 19.32  ? 214 LEU E CD1 1 
ATOM   12645 C CD2 . LEU E 2 239 ? 124.233 156.124 123.634 1.00 17.99  ? 214 LEU E CD2 1 
ATOM   12646 N N   . LYS E 2 240 ? 123.405 157.957 128.304 1.00 18.90  ? 215 LYS E N   1 
ATOM   12647 C CA  . LYS E 2 240 ? 123.245 158.069 129.745 1.00 20.16  ? 215 LYS E CA  1 
ATOM   12648 C C   . LYS E 2 240 ? 122.648 156.772 130.264 1.00 20.49  ? 215 LYS E C   1 
ATOM   12649 O O   . LYS E 2 240 ? 121.610 156.321 129.769 1.00 25.07  ? 215 LYS E O   1 
ATOM   12650 C CB  . LYS E 2 240 ? 122.363 159.260 130.118 1.00 22.92  ? 215 LYS E CB  1 
ATOM   12651 C CG  . LYS E 2 240 ? 122.354 159.564 131.604 1.00 23.39  ? 215 LYS E CG  1 
ATOM   12652 C CD  . LYS E 2 240 ? 121.490 160.770 131.919 1.00 31.70  ? 215 LYS E CD  1 
ATOM   12653 C CE  . LYS E 2 240 ? 121.488 161.065 133.409 1.00 41.97  ? 215 LYS E CE  1 
ATOM   12654 N NZ  . LYS E 2 240 ? 120.635 162.239 133.740 1.00 48.58  ? 215 LYS E NZ  1 
ATOM   12655 N N   . ARG E 2 241 ? 123.301 156.177 131.254 1.00 19.52  ? 216 ARG E N   1 
ATOM   12656 C CA  . ARG E 2 241 ? 122.861 154.892 131.766 1.00 19.65  ? 216 ARG E CA  1 
ATOM   12657 C C   . ARG E 2 241 ? 121.651 155.059 132.672 1.00 21.97  ? 216 ARG E C   1 
ATOM   12658 O O   . ARG E 2 241 ? 121.517 156.050 133.395 1.00 24.82  ? 216 ARG E O   1 
ATOM   12659 C CB  . ARG E 2 241 ? 123.991 154.205 132.531 1.00 18.27  ? 216 ARG E CB  1 
ATOM   12660 C CG  . ARG E 2 241 ? 123.806 152.712 132.693 1.00 18.34  ? 216 ARG E CG  1 
ATOM   12661 C CD  . ARG E 2 241 ? 124.956 152.097 133.462 1.00 19.02  ? 216 ARG E CD  1 
ATOM   12662 N NE  . ARG E 2 241 ? 126.214 152.235 132.742 1.00 20.03  ? 216 ARG E NE  1 
ATOM   12663 C CZ  . ARG E 2 241 ? 126.703 151.324 131.912 1.00 25.16  ? 216 ARG E CZ  1 
ATOM   12664 N NH1 . ARG E 2 241 ? 126.055 150.199 131.662 1.00 28.11  ? 216 ARG E NH1 1 
ATOM   12665 N NH2 . ARG E 2 241 ? 127.869 151.550 131.315 1.00 25.60  ? 216 ARG E NH2 1 
ATOM   12666 N N   . ASN E 2 242 ? 120.763 154.070 132.624 1.00 21.51  ? 217 ASN E N   1 
ATOM   12667 C CA  . ASN E 2 242 ? 119.577 154.065 133.468 1.00 24.99  ? 217 ASN E CA  1 
ATOM   12668 C C   . ASN E 2 242 ? 119.988 153.662 134.877 1.00 26.65  ? 217 ASN E C   1 
ATOM   12669 O O   . ASN E 2 242 ? 120.529 152.572 135.087 1.00 27.46  ? 217 ASN E O   1 
ATOM   12670 C CB  . ASN E 2 242 ? 118.519 153.119 132.907 1.00 24.05  ? 217 ASN E CB  1 
ATOM   12671 C CG  . ASN E 2 242 ? 118.082 153.500 131.505 1.00 20.84  ? 217 ASN E CG  1 
ATOM   12672 O OD1 . ASN E 2 242 ? 118.067 154.677 131.147 1.00 19.77  ? 217 ASN E OD1 1 
ATOM   12673 N ND2 . ASN E 2 242 ? 117.721 152.504 130.706 1.00 21.18  ? 217 ASN E ND2 1 
ATOM   12674 N N   . ILE E 2 243 ? 119.727 154.542 135.841 1.00 24.42  ? 218 ILE E N   1 
ATOM   12675 C CA  . ILE E 2 243 ? 120.203 154.333 137.201 1.00 24.01  ? 218 ILE E CA  1 
ATOM   12676 C C   . ILE E 2 243 ? 119.161 153.651 138.084 1.00 24.89  ? 218 ILE E C   1 
ATOM   12677 O O   . ILE E 2 243 ? 119.529 153.027 139.090 1.00 24.78  ? 218 ILE E O   1 
ATOM   12678 C CB  . ILE E 2 243 ? 120.640 155.686 137.797 1.00 23.75  ? 218 ILE E CB  1 
ATOM   12679 C CG1 . ILE E 2 243 ? 121.149 155.536 139.231 1.00 22.05  ? 218 ILE E CG1 1 
ATOM   12680 C CG2 . ILE E 2 243 ? 119.494 156.686 137.743 1.00 24.17  ? 218 ILE E CG2 1 
ATOM   12681 C CD1 . ILE E 2 243 ? 122.301 154.568 139.363 1.00 23.00  ? 218 ILE E CD1 1 
ATOM   12682 N N   . GLY E 2 244 ? 117.878 153.715 137.716 1.00 24.91  ? 219 GLY E N   1 
ATOM   12683 C CA  . GLY E 2 244 ? 116.839 153.186 138.587 1.00 23.59  ? 219 GLY E CA  1 
ATOM   12684 C C   . GLY E 2 244 ? 117.033 151.720 138.924 1.00 24.31  ? 219 GLY E C   1 
ATOM   12685 O O   . GLY E 2 244 ? 116.810 151.303 140.063 1.00 24.64  ? 219 GLY E O   1 
ATOM   12686 N N   . TYR E 2 245 ? 117.438 150.914 137.939 1.00 21.25  ? 220 TYR E N   1 
ATOM   12687 C CA  . TYR E 2 245 ? 117.603 149.486 138.189 1.00 17.70  ? 220 TYR E CA  1 
ATOM   12688 C C   . TYR E 2 245 ? 118.684 149.221 139.224 1.00 19.29  ? 220 TYR E C   1 
ATOM   12689 O O   . TYR E 2 245 ? 118.509 148.378 140.111 1.00 20.77  ? 220 TYR E O   1 
ATOM   12690 C CB  . TYR E 2 245 ? 117.936 148.752 136.897 1.00 17.57  ? 220 TYR E CB  1 
ATOM   12691 C CG  . TYR E 2 245 ? 118.598 147.417 137.134 1.00 18.79  ? 220 TYR E CG  1 
ATOM   12692 C CD1 . TYR E 2 245 ? 117.874 146.328 137.591 1.00 20.78  ? 220 TYR E CD1 1 
ATOM   12693 C CD2 . TYR E 2 245 ? 119.957 147.251 136.903 1.00 19.99  ? 220 TYR E CD2 1 
ATOM   12694 C CE1 . TYR E 2 245 ? 118.486 145.110 137.812 1.00 22.76  ? 220 TYR E CE1 1 
ATOM   12695 C CE2 . TYR E 2 245 ? 120.575 146.041 137.120 1.00 20.96  ? 220 TYR E CE2 1 
ATOM   12696 C CZ  . TYR E 2 245 ? 119.836 144.973 137.573 1.00 24.68  ? 220 TYR E CZ  1 
ATOM   12697 O OH  . TYR E 2 245 ? 120.456 143.767 137.791 1.00 24.74  ? 220 TYR E OH  1 
ATOM   12698 N N   . PHE E 2 246 ? 119.814 149.923 139.123 1.00 20.50  ? 221 PHE E N   1 
ATOM   12699 C CA  . PHE E 2 246 ? 120.909 149.654 140.046 1.00 16.46  ? 221 PHE E CA  1 
ATOM   12700 C C   . PHE E 2 246 ? 120.532 150.050 141.461 1.00 15.99  ? 221 PHE E C   1 
ATOM   12701 O O   . PHE E 2 246 ? 121.062 149.487 142.425 1.00 18.70  ? 221 PHE E O   1 
ATOM   12702 C CB  . PHE E 2 246 ? 122.175 150.379 139.594 1.00 18.15  ? 221 PHE E CB  1 
ATOM   12703 C CG  . PHE E 2 246 ? 122.688 149.920 138.261 1.00 18.23  ? 221 PHE E CG  1 
ATOM   12704 C CD1 . PHE E 2 246 ? 123.539 148.832 138.172 1.00 18.66  ? 221 PHE E CD1 1 
ATOM   12705 C CD2 . PHE E 2 246 ? 122.314 150.566 137.098 1.00 16.84  ? 221 PHE E CD2 1 
ATOM   12706 C CE1 . PHE E 2 246 ? 124.011 148.404 136.949 1.00 17.66  ? 221 PHE E CE1 1 
ATOM   12707 C CE2 . PHE E 2 246 ? 122.783 150.140 135.873 1.00 16.78  ? 221 PHE E CE2 1 
ATOM   12708 C CZ  . PHE E 2 246 ? 123.633 149.058 135.800 1.00 17.97  ? 221 PHE E CZ  1 
ATOM   12709 N N   . ILE E 2 247 ? 119.633 151.026 141.604 1.00 16.49  ? 222 ILE E N   1 
ATOM   12710 C CA  . ILE E 2 247 ? 119.199 151.443 142.932 1.00 18.21  ? 222 ILE E CA  1 
ATOM   12711 C C   . ILE E 2 247 ? 118.490 150.293 143.633 1.00 18.56  ? 222 ILE E C   1 
ATOM   12712 O O   . ILE E 2 247 ? 118.790 149.967 144.785 1.00 18.36  ? 222 ILE E O   1 
ATOM   12713 C CB  . ILE E 2 247 ? 118.298 152.686 142.837 1.00 17.86  ? 222 ILE E CB  1 
ATOM   12714 C CG1 . ILE E 2 247 ? 119.050 153.843 142.180 1.00 19.00  ? 222 ILE E CG1 1 
ATOM   12715 C CG2 . ILE E 2 247 ? 117.796 153.084 144.212 1.00 16.01  ? 222 ILE E CG2 1 
ATOM   12716 C CD1 . ILE E 2 247 ? 120.330 154.215 142.887 1.00 19.97  ? 222 ILE E CD1 1 
ATOM   12717 N N   . LEU E 2 248 ? 117.563 149.636 142.930 1.00 18.19  ? 223 LEU E N   1 
ATOM   12718 C CA  . LEU E 2 248 ? 116.840 148.520 143.531 1.00 16.43  ? 223 LEU E CA  1 
ATOM   12719 C C   . LEU E 2 248 ? 117.719 147.285 143.660 1.00 17.27  ? 223 LEU E C   1 
ATOM   12720 O O   . LEU E 2 248 ? 117.616 146.544 144.644 1.00 18.87  ? 223 LEU E O   1 
ATOM   12721 C CB  . LEU E 2 248 ? 115.600 148.194 142.701 1.00 17.00  ? 223 LEU E CB  1 
ATOM   12722 C CG  . LEU E 2 248 ? 114.367 149.075 142.888 1.00 23.97  ? 223 LEU E CG  1 
ATOM   12723 C CD1 . LEU E 2 248 ? 113.271 148.634 141.937 1.00 31.49  ? 223 LEU E CD1 1 
ATOM   12724 C CD2 . LEU E 2 248 ? 113.884 149.025 144.327 1.00 26.16  ? 223 LEU E CD2 1 
ATOM   12725 N N   . GLN E 2 249 ? 118.581 147.039 142.675 1.00 18.17  ? 224 GLN E N   1 
ATOM   12726 C CA  . GLN E 2 249 ? 119.323 145.785 142.654 1.00 16.91  ? 224 GLN E CA  1 
ATOM   12727 C C   . GLN E 2 249 ? 120.561 145.865 143.538 1.00 16.22  ? 224 GLN E C   1 
ATOM   12728 O O   . GLN E 2 249 ? 120.815 144.970 144.350 1.00 17.84  ? 224 GLN E O   1 
ATOM   12729 C CB  . GLN E 2 249 ? 119.704 145.416 141.220 1.00 18.90  ? 224 GLN E CB  1 
ATOM   12730 C CG  . GLN E 2 249 ? 120.510 144.133 141.106 1.00 24.07  ? 224 GLN E CG  1 
ATOM   12731 C CD  . GLN E 2 249 ? 119.753 142.908 141.597 1.00 31.12  ? 224 GLN E CD  1 
ATOM   12732 O OE1 . GLN E 2 249 ? 118.530 142.929 141.739 1.00 26.71  ? 224 GLN E OE1 1 
ATOM   12733 N NE2 . GLN E 2 249 ? 120.484 141.832 141.864 1.00 35.22  ? 224 GLN E NE2 1 
ATOM   12734 N N   . THR E 2 250 ? 121.351 146.924 143.375 1.00 16.22  ? 225 THR E N   1 
ATOM   12735 C CA  . THR E 2 250 ? 122.667 147.031 143.991 1.00 15.13  ? 225 THR E CA  1 
ATOM   12736 C C   . THR E 2 250 ? 122.682 147.953 145.204 1.00 16.01  ? 225 THR E C   1 
ATOM   12737 O O   . THR E 2 250 ? 123.130 147.549 146.279 1.00 16.31  ? 225 THR E O   1 
ATOM   12738 C CB  . THR E 2 250 ? 123.692 147.514 142.960 1.00 18.07  ? 225 THR E CB  1 
ATOM   12739 O OG1 . THR E 2 250 ? 123.378 148.855 142.566 1.00 24.23  ? 225 THR E OG1 1 
ATOM   12740 C CG2 . THR E 2 250 ? 123.675 146.616 141.737 1.00 22.06  ? 225 THR E CG2 1 
ATOM   12741 N N   . TYR E 2 251 ? 122.206 149.193 145.052 1.00 16.06  ? 226 TYR E N   1 
ATOM   12742 C CA  . TYR E 2 251 ? 122.345 150.165 146.132 1.00 13.04  ? 226 TYR E CA  1 
ATOM   12743 C C   . TYR E 2 251 ? 121.391 149.868 147.284 1.00 14.81  ? 226 TYR E C   1 
ATOM   12744 O O   . TYR E 2 251 ? 121.790 149.921 148.452 1.00 16.77  ? 226 TYR E O   1 
ATOM   12745 C CB  . TYR E 2 251 ? 122.125 151.576 145.591 1.00 12.95  ? 226 TYR E CB  1 
ATOM   12746 C CG  . TYR E 2 251 ? 123.272 152.068 144.739 1.00 14.25  ? 226 TYR E CG  1 
ATOM   12747 C CD1 . TYR E 2 251 ? 124.402 152.624 145.317 1.00 15.46  ? 226 TYR E CD1 1 
ATOM   12748 C CD2 . TYR E 2 251 ? 123.223 151.976 143.355 1.00 13.42  ? 226 TYR E CD2 1 
ATOM   12749 C CE1 . TYR E 2 251 ? 125.451 153.071 144.543 1.00 13.48  ? 226 TYR E CE1 1 
ATOM   12750 C CE2 . TYR E 2 251 ? 124.267 152.423 142.573 1.00 12.62  ? 226 TYR E CE2 1 
ATOM   12751 C CZ  . TYR E 2 251 ? 125.378 152.969 143.172 1.00 13.30  ? 226 TYR E CZ  1 
ATOM   12752 O OH  . TYR E 2 251 ? 126.422 153.416 142.400 1.00 19.28  ? 226 TYR E OH  1 
ATOM   12753 N N   . MET E 2 252 ? 120.123 149.570 146.984 1.00 15.98  ? 227 MET E N   1 
ATOM   12754 C CA  . MET E 2 252 ? 119.154 149.384 148.065 1.00 15.39  ? 227 MET E CA  1 
ATOM   12755 C C   . MET E 2 252 ? 119.538 148.225 148.974 1.00 14.69  ? 227 MET E C   1 
ATOM   12756 O O   . MET E 2 252 ? 119.537 148.412 150.203 1.00 14.68  ? 227 MET E O   1 
ATOM   12757 C CB  . MET E 2 252 ? 117.737 149.221 147.505 1.00 16.01  ? 227 MET E CB  1 
ATOM   12758 C CG  . MET E 2 252 ? 116.967 150.526 147.400 1.00 21.06  ? 227 MET E CG  1 
ATOM   12759 S SD  . MET E 2 252 ? 116.838 151.371 148.989 1.00 50.40  ? 227 MET E SD  1 
ATOM   12760 C CE  . MET E 2 252 ? 116.561 153.058 148.458 1.00 22.69  ? 227 MET E CE  1 
ATOM   12761 N N   . PRO E 2 253 ? 119.842 147.020 148.471 1.00 12.58  ? 228 PRO E N   1 
ATOM   12762 C CA  . PRO E 2 253 ? 120.235 145.947 149.396 1.00 12.97  ? 228 PRO E CA  1 
ATOM   12763 C C   . PRO E 2 253 ? 121.451 146.317 150.221 1.00 14.66  ? 228 PRO E C   1 
ATOM   12764 O O   . PRO E 2 253 ? 121.507 145.996 151.413 1.00 16.35  ? 228 PRO E O   1 
ATOM   12765 C CB  . PRO E 2 253 ? 120.514 144.763 148.464 1.00 12.93  ? 228 PRO E CB  1 
ATOM   12766 C CG  . PRO E 2 253 ? 119.714 145.034 147.266 1.00 14.56  ? 228 PRO E CG  1 
ATOM   12767 C CD  . PRO E 2 253 ? 119.727 146.517 147.090 1.00 14.29  ? 228 PRO E CD  1 
ATOM   12768 N N   . SER E 2 254 ? 122.425 147.005 149.619 1.00 14.54  ? 229 SER E N   1 
ATOM   12769 C CA  . SER E 2 254 ? 123.596 147.424 150.378 1.00 14.10  ? 229 SER E CA  1 
ATOM   12770 C C   . SER E 2 254 ? 123.210 148.412 151.469 1.00 12.79  ? 229 SER E C   1 
ATOM   12771 O O   . SER E 2 254 ? 123.748 148.360 152.581 1.00 12.37  ? 229 SER E O   1 
ATOM   12772 C CB  . SER E 2 254 ? 124.635 148.038 149.441 1.00 15.32  ? 229 SER E CB  1 
ATOM   12773 O OG  . SER E 2 254 ? 125.056 147.102 148.465 1.00 15.44  ? 229 SER E OG  1 
ATOM   12774 N N   . ILE E 2 255 ? 122.293 149.334 151.165 1.00 13.76  ? 230 ILE E N   1 
ATOM   12775 C CA  . ILE E 2 255 ? 121.859 150.298 152.172 1.00 13.54  ? 230 ILE E CA  1 
ATOM   12776 C C   . ILE E 2 255 ? 121.169 149.576 153.321 1.00 12.77  ? 230 ILE E C   1 
ATOM   12777 O O   . ILE E 2 255 ? 121.437 149.842 154.498 1.00 13.39  ? 230 ILE E O   1 
ATOM   12778 C CB  . ILE E 2 255 ? 120.942 151.364 151.545 1.00 14.68  ? 230 ILE E CB  1 
ATOM   12779 C CG1 . ILE E 2 255 ? 121.731 152.251 150.585 1.00 13.07  ? 230 ILE E CG1 1 
ATOM   12780 C CG2 . ILE E 2 255 ? 120.284 152.204 152.622 1.00 11.04  ? 230 ILE E CG2 1 
ATOM   12781 C CD1 . ILE E 2 255 ? 120.865 153.057 149.644 1.00 14.70  ? 230 ILE E CD1 1 
ATOM   12782 N N   . LEU E 2 256 ? 120.272 148.642 152.992 1.00 12.10  ? 231 LEU E N   1 
ATOM   12783 C CA  . LEU E 2 256 ? 119.512 147.951 154.028 1.00 12.79  ? 231 LEU E CA  1 
ATOM   12784 C C   . LEU E 2 256 ? 120.420 147.094 154.901 1.00 12.97  ? 231 LEU E C   1 
ATOM   12785 O O   . LEU E 2 256 ? 120.274 147.081 156.128 1.00 12.44  ? 231 LEU E O   1 
ATOM   12786 C CB  . LEU E 2 256 ? 118.414 147.101 153.391 1.00 11.97  ? 231 LEU E CB  1 
ATOM   12787 C CG  . LEU E 2 256 ? 117.298 147.870 152.678 1.00 12.88  ? 231 LEU E CG  1 
ATOM   12788 C CD1 . LEU E 2 256 ? 116.235 146.919 152.156 1.00 14.26  ? 231 LEU E CD1 1 
ATOM   12789 C CD2 . LEU E 2 256 ? 116.684 148.913 153.596 1.00 9.61   ? 231 LEU E CD2 1 
ATOM   12790 N N   . ILE E 2 257 ? 121.351 146.358 154.287 1.00 15.27  ? 232 ILE E N   1 
ATOM   12791 C CA  . ILE E 2 257 ? 122.281 145.549 155.070 1.00 12.74  ? 232 ILE E CA  1 
ATOM   12792 C C   . ILE E 2 257 ? 123.119 146.445 155.968 1.00 14.04  ? 232 ILE E C   1 
ATOM   12793 O O   . ILE E 2 257 ? 123.437 146.088 157.109 1.00 16.97  ? 232 ILE E O   1 
ATOM   12794 C CB  . ILE E 2 257 ? 123.158 144.679 154.153 1.00 10.03  ? 232 ILE E CB  1 
ATOM   12795 C CG1 . ILE E 2 257 ? 122.286 143.749 153.315 1.00 10.26  ? 232 ILE E CG1 1 
ATOM   12796 C CG2 . ILE E 2 257 ? 124.128 143.854 154.980 1.00 8.99   ? 232 ILE E CG2 1 
ATOM   12797 C CD1 . ILE E 2 257 ? 121.538 142.734 154.134 1.00 12.13  ? 232 ILE E CD1 1 
ATOM   12798 N N   . THR E 2 258 ? 123.499 147.621 155.463 1.00 14.28  ? 233 THR E N   1 
ATOM   12799 C CA  . THR E 2 258 ? 124.263 148.553 156.281 1.00 15.11  ? 233 THR E CA  1 
ATOM   12800 C C   . THR E 2 258 ? 123.435 149.011 157.471 1.00 17.94  ? 233 THR E C   1 
ATOM   12801 O O   . THR E 2 258 ? 123.941 149.100 158.595 1.00 19.40  ? 233 THR E O   1 
ATOM   12802 C CB  . THR E 2 258 ? 124.717 149.746 155.440 1.00 15.06  ? 233 THR E CB  1 
ATOM   12803 O OG1 . THR E 2 258 ? 125.387 149.273 154.266 1.00 15.57  ? 233 THR E OG1 1 
ATOM   12804 C CG2 . THR E 2 258 ? 125.669 150.622 156.231 1.00 13.50  ? 233 THR E CG2 1 
ATOM   12805 N N   . ILE E 2 259 ? 122.154 149.313 157.240 1.00 16.45  ? 234 ILE E N   1 
ATOM   12806 C CA  . ILE E 2 259 ? 121.277 149.687 158.343 1.00 15.63  ? 234 ILE E CA  1 
ATOM   12807 C C   . ILE E 2 259 ? 121.090 148.503 159.280 1.00 17.16  ? 234 ILE E C   1 
ATOM   12808 O O   . ILE E 2 259 ? 120.993 148.665 160.502 1.00 20.32  ? 234 ILE E O   1 
ATOM   12809 C CB  . ILE E 2 259 ? 119.931 150.204 157.801 1.00 11.70  ? 234 ILE E CB  1 
ATOM   12810 C CG1 . ILE E 2 259 ? 120.151 151.425 156.909 1.00 11.81  ? 234 ILE E CG1 1 
ATOM   12811 C CG2 . ILE E 2 259 ? 118.984 150.543 158.939 1.00 11.12  ? 234 ILE E CG2 1 
ATOM   12812 C CD1 . ILE E 2 259 ? 118.924 151.843 156.139 1.00 10.71  ? 234 ILE E CD1 1 
ATOM   12813 N N   . LEU E 2 260 ? 121.041 147.290 158.721 1.00 15.21  ? 235 LEU E N   1 
ATOM   12814 C CA  . LEU E 2 260 ? 120.910 146.099 159.552 1.00 14.73  ? 235 LEU E CA  1 
ATOM   12815 C C   . LEU E 2 260 ? 122.095 145.954 160.492 1.00 16.67  ? 235 LEU E C   1 
ATOM   12816 O O   . LEU E 2 260 ? 121.928 145.576 161.656 1.00 22.31  ? 235 LEU E O   1 
ATOM   12817 C CB  . LEU E 2 260 ? 120.766 144.854 158.679 1.00 14.64  ? 235 LEU E CB  1 
ATOM   12818 C CG  . LEU E 2 260 ? 119.406 144.161 158.703 1.00 11.30  ? 235 LEU E CG  1 
ATOM   12819 C CD1 . LEU E 2 260 ? 118.293 145.175 158.632 1.00 10.68  ? 235 LEU E CD1 1 
ATOM   12820 C CD2 . LEU E 2 260 ? 119.301 143.170 157.559 1.00 10.41  ? 235 LEU E CD2 1 
ATOM   12821 N N   . SER E 2 261 ? 123.305 146.227 159.999 1.00 13.94  ? 236 SER E N   1 
ATOM   12822 C CA  . SER E 2 261 ? 124.473 146.084 160.854 1.00 13.16  ? 236 SER E CA  1 
ATOM   12823 C C   . SER E 2 261 ? 124.409 147.017 162.054 1.00 18.67  ? 236 SER E C   1 
ATOM   12824 O O   . SER E 2 261 ? 125.061 146.750 163.068 1.00 20.14  ? 236 SER E O   1 
ATOM   12825 C CB  . SER E 2 261 ? 125.747 146.338 160.050 1.00 12.53  ? 236 SER E CB  1 
ATOM   12826 O OG  . SER E 2 261 ? 125.754 147.645 159.508 1.00 15.00  ? 236 SER E OG  1 
ATOM   12827 N N   . TRP E 2 262 ? 123.634 148.101 161.963 1.00 18.09  ? 237 TRP E N   1 
ATOM   12828 C CA  . TRP E 2 262 ? 123.455 148.998 163.094 1.00 16.76  ? 237 TRP E CA  1 
ATOM   12829 C C   . TRP E 2 262 ? 122.434 148.486 164.097 1.00 18.19  ? 237 TRP E C   1 
ATOM   12830 O O   . TRP E 2 262 ? 122.354 149.033 165.201 1.00 20.46  ? 237 TRP E O   1 
ATOM   12831 C CB  . TRP E 2 262 ? 123.040 150.389 162.609 1.00 16.36  ? 237 TRP E CB  1 
ATOM   12832 C CG  . TRP E 2 262 ? 123.918 150.940 161.535 1.00 17.43  ? 237 TRP E CG  1 
ATOM   12833 C CD1 . TRP E 2 262 ? 125.221 150.620 161.297 1.00 19.42  ? 237 TRP E CD1 1 
ATOM   12834 C CD2 . TRP E 2 262 ? 123.552 151.901 160.540 1.00 18.39  ? 237 TRP E CD2 1 
ATOM   12835 N NE1 . TRP E 2 262 ? 125.693 151.328 160.220 1.00 24.40  ? 237 TRP E NE1 1 
ATOM   12836 C CE2 . TRP E 2 262 ? 124.687 152.122 159.737 1.00 23.13  ? 237 TRP E CE2 1 
ATOM   12837 C CE3 . TRP E 2 262 ? 122.376 152.600 160.253 1.00 18.49  ? 237 TRP E CE3 1 
ATOM   12838 C CZ2 . TRP E 2 262 ? 124.680 153.011 158.665 1.00 22.82  ? 237 TRP E CZ2 1 
ATOM   12839 C CZ3 . TRP E 2 262 ? 122.372 153.482 159.189 1.00 21.29  ? 237 TRP E CZ3 1 
ATOM   12840 C CH2 . TRP E 2 262 ? 123.516 153.679 158.408 1.00 23.15  ? 237 TRP E CH2 1 
ATOM   12841 N N   . VAL E 2 263 ? 121.647 147.466 163.742 1.00 17.50  ? 238 VAL E N   1 
ATOM   12842 C CA  . VAL E 2 263 ? 120.755 146.849 164.719 1.00 21.21  ? 238 VAL E CA  1 
ATOM   12843 C C   . VAL E 2 263 ? 121.564 146.309 165.889 1.00 21.32  ? 238 VAL E C   1 
ATOM   12844 O O   . VAL E 2 263 ? 121.060 146.208 167.014 1.00 23.85  ? 238 VAL E O   1 
ATOM   12845 C CB  . VAL E 2 263 ? 119.896 145.758 164.043 1.00 20.32  ? 238 VAL E CB  1 
ATOM   12846 C CG1 . VAL E 2 263 ? 119.169 144.900 165.070 1.00 19.64  ? 238 VAL E CG1 1 
ATOM   12847 C CG2 . VAL E 2 263 ? 118.909 146.389 163.074 1.00 19.74  ? 238 VAL E CG2 1 
ATOM   12848 N N   . SER E 2 264 ? 122.841 145.995 165.655 1.00 19.04  ? 239 SER E N   1 
ATOM   12849 C CA  . SER E 2 264 ? 123.686 145.501 166.733 1.00 22.75  ? 239 SER E CA  1 
ATOM   12850 C C   . SER E 2 264 ? 123.859 146.554 167.816 1.00 25.57  ? 239 SER E C   1 
ATOM   12851 O O   . SER E 2 264 ? 123.973 146.216 168.999 1.00 29.41  ? 239 SER E O   1 
ATOM   12852 C CB  . SER E 2 264 ? 125.046 145.071 166.182 1.00 21.76  ? 239 SER E CB  1 
ATOM   12853 O OG  . SER E 2 264 ? 125.901 144.632 167.221 1.00 17.47  ? 239 SER E OG  1 
ATOM   12854 N N   . PHE E 2 265 ? 123.881 147.832 167.433 1.00 22.39  ? 240 PHE E N   1 
ATOM   12855 C CA  . PHE E 2 265 ? 124.067 148.897 168.408 1.00 22.02  ? 240 PHE E CA  1 
ATOM   12856 C C   . PHE E 2 265 ? 122.863 149.053 169.326 1.00 25.38  ? 240 PHE E C   1 
ATOM   12857 O O   . PHE E 2 265 ? 122.974 149.724 170.358 1.00 27.55  ? 240 PHE E O   1 
ATOM   12858 C CB  . PHE E 2 265 ? 124.370 150.210 167.688 1.00 20.43  ? 240 PHE E CB  1 
ATOM   12859 C CG  . PHE E 2 265 ? 125.476 150.101 166.675 1.00 20.07  ? 240 PHE E CG  1 
ATOM   12860 C CD1 . PHE E 2 265 ? 126.558 149.266 166.897 1.00 21.90  ? 240 PHE E CD1 1 
ATOM   12861 C CD2 . PHE E 2 265 ? 125.434 150.831 165.503 1.00 19.26  ? 240 PHE E CD2 1 
ATOM   12862 C CE1 . PHE E 2 265 ? 127.573 149.163 165.971 1.00 20.55  ? 240 PHE E CE1 1 
ATOM   12863 C CE2 . PHE E 2 265 ? 126.448 150.730 164.573 1.00 17.53  ? 240 PHE E CE2 1 
ATOM   12864 C CZ  . PHE E 2 265 ? 127.518 149.896 164.808 1.00 18.32  ? 240 PHE E CZ  1 
ATOM   12865 N N   . TRP E 2 266 ? 121.723 148.465 168.971 1.00 25.49  ? 241 TRP E N   1 
ATOM   12866 C CA  . TRP E 2 266 ? 120.505 148.545 169.763 1.00 24.00  ? 241 TRP E CA  1 
ATOM   12867 C C   . TRP E 2 266 ? 120.222 147.242 170.499 1.00 26.97  ? 241 TRP E C   1 
ATOM   12868 O O   . TRP E 2 266 ? 119.128 147.071 171.044 1.00 28.95  ? 241 TRP E O   1 
ATOM   12869 C CB  . TRP E 2 266 ? 119.314 148.911 168.875 1.00 19.74  ? 241 TRP E CB  1 
ATOM   12870 C CG  . TRP E 2 266 ? 119.491 150.172 168.081 1.00 20.56  ? 241 TRP E CG  1 
ATOM   12871 C CD1 . TRP E 2 266 ? 120.130 150.306 166.884 1.00 18.76  ? 241 TRP E CD1 1 
ATOM   12872 C CD2 . TRP E 2 266 ? 119.002 151.474 168.422 1.00 23.33  ? 241 TRP E CD2 1 
ATOM   12873 N NE1 . TRP E 2 266 ? 120.078 151.612 166.463 1.00 18.27  ? 241 TRP E NE1 1 
ATOM   12874 C CE2 . TRP E 2 266 ? 119.390 152.349 167.389 1.00 19.91  ? 241 TRP E CE2 1 
ATOM   12875 C CE3 . TRP E 2 266 ? 118.277 151.985 169.502 1.00 26.18  ? 241 TRP E CE3 1 
ATOM   12876 C CZ2 . TRP E 2 266 ? 119.079 153.706 167.405 1.00 20.87  ? 241 TRP E CZ2 1 
ATOM   12877 C CZ3 . TRP E 2 266 ? 117.970 153.333 169.516 1.00 25.30  ? 241 TRP E CZ3 1 
ATOM   12878 C CH2 . TRP E 2 266 ? 118.370 154.177 168.475 1.00 23.16  ? 241 TRP E CH2 1 
ATOM   12879 N N   . ILE E 2 267 ? 121.190 146.330 170.533 1.00 27.91  ? 242 ILE E N   1 
ATOM   12880 C CA  . ILE E 2 267 ? 121.081 145.066 171.248 1.00 26.11  ? 242 ILE E CA  1 
ATOM   12881 C C   . ILE E 2 267 ? 121.996 145.122 172.461 1.00 31.87  ? 242 ILE E C   1 
ATOM   12882 O O   . ILE E 2 267 ? 123.030 145.800 172.451 1.00 36.74  ? 242 ILE E O   1 
ATOM   12883 C CB  . ILE E 2 267 ? 121.441 143.883 170.321 1.00 24.58  ? 242 ILE E CB  1 
ATOM   12884 C CG1 . ILE E 2 267 ? 120.519 143.870 169.102 1.00 21.96  ? 242 ILE E CG1 1 
ATOM   12885 C CG2 . ILE E 2 267 ? 121.333 142.553 171.048 1.00 32.90  ? 242 ILE E CG2 1 
ATOM   12886 C CD1 . ILE E 2 267 ? 120.874 142.820 168.080 1.00 20.10  ? 242 ILE E CD1 1 
ATOM   12887 N N   . ASN E 2 268 ? 121.600 144.418 173.520 1.00 38.24  ? 243 ASN E N   1 
ATOM   12888 C CA  . ASN E 2 268 ? 122.357 144.438 174.763 1.00 47.40  ? 243 ASN E CA  1 
ATOM   12889 C C   . ASN E 2 268 ? 123.795 143.992 174.530 1.00 50.08  ? 243 ASN E C   1 
ATOM   12890 O O   . ASN E 2 268 ? 124.065 143.113 173.708 1.00 45.91  ? 243 ASN E O   1 
ATOM   12891 C CB  . ASN E 2 268 ? 121.685 143.532 175.793 1.00 50.35  ? 243 ASN E CB  1 
ATOM   12892 C CG  . ASN E 2 268 ? 120.384 144.108 176.310 1.00 61.46  ? 243 ASN E CG  1 
ATOM   12893 O OD1 . ASN E 2 268 ? 120.086 145.283 176.100 1.00 71.27  ? 243 ASN E OD1 1 
ATOM   12894 N ND2 . ASN E 2 268 ? 119.594 143.278 176.981 1.00 57.01  ? 243 ASN E ND2 1 
ATOM   12895 N N   . TYR E 2 269 ? 124.725 144.618 175.258 1.00 55.53  ? 244 TYR E N   1 
ATOM   12896 C CA  . TYR E 2 269 ? 126.137 144.273 175.122 1.00 53.83  ? 244 TYR E CA  1 
ATOM   12897 C C   . TYR E 2 269 ? 126.401 142.809 175.447 1.00 54.99  ? 244 TYR E C   1 
ATOM   12898 O O   . TYR E 2 269 ? 127.367 142.226 174.941 1.00 50.75  ? 244 TYR E O   1 
ATOM   12899 C CB  . TYR E 2 269 ? 126.988 145.174 176.018 1.00 58.35  ? 244 TYR E CB  1 
ATOM   12900 C CG  . TYR E 2 269 ? 126.869 144.861 177.492 1.00 65.27  ? 244 TYR E CG  1 
ATOM   12901 C CD1 . TYR E 2 269 ? 125.830 145.384 178.250 1.00 70.86  ? 244 TYR E CD1 1 
ATOM   12902 C CD2 . TYR E 2 269 ? 127.797 144.045 178.127 1.00 65.96  ? 244 TYR E CD2 1 
ATOM   12903 C CE1 . TYR E 2 269 ? 125.716 145.101 179.597 1.00 76.53  ? 244 TYR E CE1 1 
ATOM   12904 C CE2 . TYR E 2 269 ? 127.691 143.756 179.473 1.00 71.55  ? 244 TYR E CE2 1 
ATOM   12905 C CZ  . TYR E 2 269 ? 126.649 144.287 180.204 1.00 76.39  ? 244 TYR E CZ  1 
ATOM   12906 O OH  . TYR E 2 269 ? 126.540 144.005 181.546 1.00 74.94  ? 244 TYR E OH  1 
ATOM   12907 N N   . ASP E 2 270 ? 125.563 142.201 176.284 1.00 56.67  ? 245 ASP E N   1 
ATOM   12908 C CA  . ASP E 2 270 ? 125.782 140.839 176.749 1.00 52.55  ? 245 ASP E CA  1 
ATOM   12909 C C   . ASP E 2 270 ? 125.245 139.777 175.800 1.00 46.50  ? 245 ASP E C   1 
ATOM   12910 O O   . ASP E 2 270 ? 125.527 138.592 176.003 1.00 49.14  ? 245 ASP E O   1 
ATOM   12911 C CB  . ASP E 2 270 ? 125.146 140.647 178.130 1.00 56.17  ? 245 ASP E CB  1 
ATOM   12912 C CG  . ASP E 2 270 ? 123.672 140.999 178.147 1.00 58.27  ? 245 ASP E CG  1 
ATOM   12913 O OD1 . ASP E 2 270 ? 122.850 140.145 177.754 1.00 59.84  ? 245 ASP E OD1 1 
ATOM   12914 O OD2 . ASP E 2 270 ? 123.333 142.131 178.551 1.00 58.72  ? 245 ASP E OD2 1 
ATOM   12915 N N   . ALA E 2 271 ? 124.493 140.162 174.769 1.00 43.22  ? 246 ALA E N   1 
ATOM   12916 C CA  . ALA E 2 271 ? 123.979 139.201 173.796 1.00 35.91  ? 246 ALA E CA  1 
ATOM   12917 C C   . ALA E 2 271 ? 125.042 138.886 172.741 1.00 25.77  ? 246 ALA E C   1 
ATOM   12918 O O   . ALA E 2 271 ? 124.892 139.167 171.553 1.00 24.13  ? 246 ALA E O   1 
ATOM   12919 C CB  . ALA E 2 271 ? 122.701 139.728 173.158 1.00 32.41  ? 246 ALA E CB  1 
ATOM   12920 N N   . SER E 2 272 ? 126.145 138.299 173.213 1.00 22.98  ? 247 SER E N   1 
ATOM   12921 C CA  . SER E 2 272 ? 127.286 138.055 172.336 1.00 24.07  ? 247 SER E CA  1 
ATOM   12922 C C   . SER E 2 272 ? 126.900 137.156 171.170 1.00 19.25  ? 247 SER E C   1 
ATOM   12923 O O   . SER E 2 272 ? 127.290 137.411 170.026 1.00 18.85  ? 247 SER E O   1 
ATOM   12924 C CB  . SER E 2 272 ? 128.438 137.440 173.130 1.00 26.87  ? 247 SER E CB  1 
ATOM   12925 O OG  . SER E 2 272 ? 128.009 136.296 173.847 1.00 34.82  ? 247 SER E OG  1 
ATOM   12926 N N   . ALA E 2 273 ? 126.132 136.099 171.442 1.00 16.51  ? 248 ALA E N   1 
ATOM   12927 C CA  . ALA E 2 273 ? 125.739 135.185 170.377 1.00 12.96  ? 248 ALA E CA  1 
ATOM   12928 C C   . ALA E 2 273 ? 124.876 135.893 169.343 1.00 13.61  ? 248 ALA E C   1 
ATOM   12929 O O   . ALA E 2 273 ? 125.062 135.707 168.135 1.00 12.55  ? 248 ALA E O   1 
ATOM   12930 C CB  . ALA E 2 273 ? 125.003 133.982 170.963 1.00 11.79  ? 248 ALA E CB  1 
ATOM   12931 N N   . ALA E 2 274 ? 123.915 136.699 169.802 1.00 17.28  ? 249 ALA E N   1 
ATOM   12932 C CA  . ALA E 2 274 ? 123.020 137.393 168.882 1.00 14.14  ? 249 ALA E CA  1 
ATOM   12933 C C   . ALA E 2 274 ? 123.759 138.440 168.058 1.00 13.70  ? 249 ALA E C   1 
ATOM   12934 O O   . ALA E 2 274 ? 123.535 138.555 166.847 1.00 12.74  ? 249 ALA E O   1 
ATOM   12935 C CB  . ALA E 2 274 ? 121.871 138.038 169.656 1.00 15.81  ? 249 ALA E CB  1 
ATOM   12936 N N   . ARG E 2 275 ? 124.643 139.213 168.694 1.00 14.90  ? 250 ARG E N   1 
ATOM   12937 C CA  . ARG E 2 275 ? 125.295 140.320 168.002 1.00 13.35  ? 250 ARG E CA  1 
ATOM   12938 C C   . ARG E 2 275 ? 126.408 139.859 167.070 1.00 13.46  ? 250 ARG E C   1 
ATOM   12939 O O   . ARG E 2 275 ? 126.619 140.475 166.020 1.00 14.31  ? 250 ARG E O   1 
ATOM   12940 C CB  . ARG E 2 275 ? 125.850 141.319 169.017 1.00 18.03  ? 250 ARG E CB  1 
ATOM   12941 C CG  . ARG E 2 275 ? 124.789 142.019 169.843 1.00 24.38  ? 250 ARG E CG  1 
ATOM   12942 C CD  . ARG E 2 275 ? 125.394 143.121 170.692 1.00 32.66  ? 250 ARG E CD  1 
ATOM   12943 N NE  . ARG E 2 275 ? 126.044 144.146 169.885 1.00 31.42  ? 250 ARG E NE  1 
ATOM   12944 C CZ  . ARG E 2 275 ? 126.491 145.300 170.361 1.00 32.08  ? 250 ARG E CZ  1 
ATOM   12945 N NH1 . ARG E 2 275 ? 126.351 145.622 171.636 1.00 33.92  ? 250 ARG E NH1 1 
ATOM   12946 N NH2 . ARG E 2 275 ? 127.083 146.157 169.534 1.00 29.94  ? 250 ARG E NH2 1 
ATOM   12947 N N   . VAL E 2 276 ? 127.123 138.788 167.421 1.00 13.28  ? 251 VAL E N   1 
ATOM   12948 C CA  . VAL E 2 276 ? 128.122 138.248 166.504 1.00 11.69  ? 251 VAL E CA  1 
ATOM   12949 C C   . VAL E 2 276 ? 127.446 137.583 165.314 1.00 10.01  ? 251 VAL E C   1 
ATOM   12950 O O   . VAL E 2 276 ? 127.890 137.732 164.170 1.00 8.83   ? 251 VAL E O   1 
ATOM   12951 C CB  . VAL E 2 276 ? 129.067 137.283 167.242 1.00 11.32  ? 251 VAL E CB  1 
ATOM   12952 C CG1 . VAL E 2 276 ? 129.977 136.585 166.257 1.00 7.91   ? 251 VAL E CG1 1 
ATOM   12953 C CG2 . VAL E 2 276 ? 129.897 138.046 168.255 1.00 11.60  ? 251 VAL E CG2 1 
ATOM   12954 N N   . ALA E 2 277 ? 126.364 136.841 165.559 1.00 10.68  ? 252 ALA E N   1 
ATOM   12955 C CA  . ALA E 2 277 ? 125.662 136.185 164.462 1.00 9.89   ? 252 ALA E CA  1 
ATOM   12956 C C   . ALA E 2 277 ? 125.099 137.216 163.495 1.00 9.90   ? 252 ALA E C   1 
ATOM   12957 O O   . ALA E 2 277 ? 125.176 137.042 162.274 1.00 10.75  ? 252 ALA E O   1 
ATOM   12958 C CB  . ALA E 2 277 ? 124.552 135.286 165.002 1.00 11.50  ? 252 ALA E CB  1 
ATOM   12959 N N   . LEU E 2 278 ? 124.518 138.293 164.027 1.00 9.62   ? 253 LEU E N   1 
ATOM   12960 C CA  . LEU E 2 278 ? 124.038 139.376 163.177 1.00 9.65   ? 253 LEU E CA  1 
ATOM   12961 C C   . LEU E 2 278 ? 125.197 140.060 162.463 1.00 10.45  ? 253 LEU E C   1 
ATOM   12962 O O   . LEU E 2 278 ? 125.118 140.343 161.262 1.00 10.96  ? 253 LEU E O   1 
ATOM   12963 C CB  . LEU E 2 278 ? 123.255 140.384 164.024 1.00 8.68   ? 253 LEU E CB  1 
ATOM   12964 C CG  . LEU E 2 278 ? 122.227 141.351 163.423 1.00 9.10   ? 253 LEU E CG  1 
ATOM   12965 C CD1 . LEU E 2 278 ? 121.508 142.085 164.539 1.00 12.66  ? 253 LEU E CD1 1 
ATOM   12966 C CD2 . LEU E 2 278 ? 122.832 142.351 162.453 1.00 8.59   ? 253 LEU E CD2 1 
ATOM   12967 N N   . GLY E 2 279 ? 126.288 140.319 163.185 1.00 9.27   ? 254 GLY E N   1 
ATOM   12968 C CA  . GLY E 2 279 ? 127.412 141.026 162.593 1.00 7.85   ? 254 GLY E CA  1 
ATOM   12969 C C   . GLY E 2 279 ? 128.123 140.249 161.501 1.00 9.22   ? 254 GLY E C   1 
ATOM   12970 O O   . GLY E 2 279 ? 128.434 140.800 160.443 1.00 9.66   ? 254 GLY E O   1 
ATOM   12971 N N   . ILE E 2 280 ? 128.385 138.962 161.732 1.00 9.11   ? 255 ILE E N   1 
ATOM   12972 C CA  . ILE E 2 280 ? 129.149 138.201 160.749 1.00 7.38   ? 255 ILE E CA  1 
ATOM   12973 C C   . ILE E 2 280 ? 128.282 137.789 159.566 1.00 7.17   ? 255 ILE E C   1 
ATOM   12974 O O   . ILE E 2 280 ? 128.789 137.623 158.452 1.00 8.25   ? 255 ILE E O   1 
ATOM   12975 C CB  . ILE E 2 280 ? 129.815 136.979 161.406 1.00 7.20   ? 255 ILE E CB  1 
ATOM   12976 C CG1 . ILE E 2 280 ? 130.885 136.392 160.486 1.00 6.44   ? 255 ILE E CG1 1 
ATOM   12977 C CG2 . ILE E 2 280 ? 128.789 135.911 161.734 1.00 7.69   ? 255 ILE E CG2 1 
ATOM   12978 C CD1 . ILE E 2 280 ? 132.012 137.345 160.172 1.00 6.11   ? 255 ILE E CD1 1 
ATOM   12979 N N   . THR E 2 281 ? 126.974 137.628 159.768 1.00 7.39   ? 256 THR E N   1 
ATOM   12980 C CA  . THR E 2 281 ? 126.113 137.240 158.658 1.00 7.30   ? 256 THR E CA  1 
ATOM   12981 C C   . THR E 2 281 ? 125.827 138.413 157.731 1.00 8.13   ? 256 THR E C   1 
ATOM   12982 O O   . THR E 2 281 ? 125.642 138.210 156.526 1.00 8.05   ? 256 THR E O   1 
ATOM   12983 C CB  . THR E 2 281 ? 124.808 136.641 159.175 1.00 6.36   ? 256 THR E CB  1 
ATOM   12984 O OG1 . THR E 2 281 ? 125.095 135.686 160.204 1.00 7.40   ? 256 THR E OG1 1 
ATOM   12985 C CG2 . THR E 2 281 ? 124.063 135.945 158.049 1.00 5.20   ? 256 THR E CG2 1 
ATOM   12986 N N   . THR E 2 282 ? 125.793 139.639 158.261 1.00 7.92   ? 257 THR E N   1 
ATOM   12987 C CA  . THR E 2 282 ? 125.696 140.798 157.383 1.00 7.24   ? 257 THR E CA  1 
ATOM   12988 C C   . THR E 2 282 ? 126.993 141.017 156.620 1.00 8.50   ? 257 THR E C   1 
ATOM   12989 O O   . THR E 2 282 ? 126.964 141.468 155.470 1.00 10.51  ? 257 THR E O   1 
ATOM   12990 C CB  . THR E 2 282 ? 125.332 142.050 158.179 1.00 7.73   ? 257 THR E CB  1 
ATOM   12991 O OG1 . THR E 2 282 ? 126.244 142.205 159.273 1.00 8.95   ? 257 THR E OG1 1 
ATOM   12992 C CG2 . THR E 2 282 ? 123.913 141.946 158.713 1.00 8.91   ? 257 THR E CG2 1 
ATOM   12993 N N   . VAL E 2 283 ? 128.138 140.715 157.240 1.00 7.92   ? 258 VAL E N   1 
ATOM   12994 C CA  . VAL E 2 283 ? 129.396 140.733 156.501 1.00 6.61   ? 258 VAL E CA  1 
ATOM   12995 C C   . VAL E 2 283 ? 129.363 139.676 155.408 1.00 7.18   ? 258 VAL E C   1 
ATOM   12996 O O   . VAL E 2 283 ? 129.777 139.922 154.269 1.00 8.42   ? 258 VAL E O   1 
ATOM   12997 C CB  . VAL E 2 283 ? 130.587 140.532 157.455 1.00 5.60   ? 258 VAL E CB  1 
ATOM   12998 C CG1 . VAL E 2 283 ? 131.846 140.214 156.673 1.00 5.62   ? 258 VAL E CG1 1 
ATOM   12999 C CG2 . VAL E 2 283 ? 130.794 141.770 158.302 1.00 7.96   ? 258 VAL E CG2 1 
ATOM   13000 N N   . LEU E 2 284 ? 128.864 138.482 155.738 1.00 7.30   ? 259 LEU E N   1 
ATOM   13001 C CA  . LEU E 2 284 ? 128.689 137.445 154.728 1.00 6.18   ? 259 LEU E CA  1 
ATOM   13002 C C   . LEU E 2 284 ? 127.707 137.897 153.656 1.00 7.54   ? 259 LEU E C   1 
ATOM   13003 O O   . LEU E 2 284 ? 127.912 137.632 152.465 1.00 9.42   ? 259 LEU E O   1 
ATOM   13004 C CB  . LEU E 2 284 ? 128.229 136.144 155.381 1.00 5.79   ? 259 LEU E CB  1 
ATOM   13005 C CG  . LEU E 2 284 ? 127.832 135.008 154.441 1.00 5.59   ? 259 LEU E CG  1 
ATOM   13006 C CD1 . LEU E 2 284 ? 128.996 134.610 153.562 1.00 5.33   ? 259 LEU E CD1 1 
ATOM   13007 C CD2 . LEU E 2 284 ? 127.369 133.819 155.256 1.00 6.30   ? 259 LEU E CD2 1 
ATOM   13008 N N   . THR E 2 285 ? 126.625 138.567 154.061 1.00 8.07   ? 260 THR E N   1 
ATOM   13009 C CA  . THR E 2 285 ? 125.640 139.030 153.090 1.00 7.36   ? 260 THR E CA  1 
ATOM   13010 C C   . THR E 2 285 ? 126.257 140.065 152.161 1.00 10.21  ? 260 THR E C   1 
ATOM   13011 O O   . THR E 2 285 ? 125.997 140.061 150.953 1.00 13.49  ? 260 THR E O   1 
ATOM   13012 C CB  . THR E 2 285 ? 124.419 139.610 153.800 1.00 7.11   ? 260 THR E CB  1 
ATOM   13013 O OG1 . THR E 2 285 ? 123.966 138.692 154.802 1.00 8.73   ? 260 THR E OG1 1 
ATOM   13014 C CG2 . THR E 2 285 ? 123.302 139.853 152.803 1.00 6.89   ? 260 THR E CG2 1 
ATOM   13015 N N   . MET E 2 286 ? 127.073 140.966 152.714 1.00 9.28   ? 261 MET E N   1 
ATOM   13016 C CA  . MET E 2 286 ? 127.739 141.967 151.889 1.00 8.70   ? 261 MET E CA  1 
ATOM   13017 C C   . MET E 2 286 ? 128.688 141.307 150.901 1.00 12.01  ? 261 MET E C   1 
ATOM   13018 O O   . MET E 2 286 ? 128.766 141.715 149.737 1.00 15.42  ? 261 MET E O   1 
ATOM   13019 C CB  . MET E 2 286 ? 128.486 142.972 152.762 1.00 8.47   ? 261 MET E CB  1 
ATOM   13020 C CG  . MET E 2 286 ? 128.839 144.260 152.037 1.00 12.01  ? 261 MET E CG  1 
ATOM   13021 S SD  . MET E 2 286 ? 127.420 145.156 151.393 1.00 13.31  ? 261 MET E SD  1 
ATOM   13022 C CE  . MET E 2 286 ? 126.527 145.486 152.902 1.00 14.17  ? 261 MET E CE  1 
ATOM   13023 N N   . THR E 2 287 ? 129.424 140.286 151.348 1.00 10.82  ? 262 THR E N   1 
ATOM   13024 C CA  . THR E 2 287 ? 130.279 139.549 150.426 1.00 10.74  ? 262 THR E CA  1 
ATOM   13025 C C   . THR E 2 287 ? 129.450 138.869 149.347 1.00 14.58  ? 262 THR E C   1 
ATOM   13026 O O   . THR E 2 287 ? 129.823 138.892 148.171 1.00 23.15  ? 262 THR E O   1 
ATOM   13027 C CB  . THR E 2 287 ? 131.121 138.515 151.172 1.00 10.03  ? 262 THR E CB  1 
ATOM   13028 O OG1 . THR E 2 287 ? 130.260 137.617 151.879 1.00 16.39  ? 262 THR E OG1 1 
ATOM   13029 C CG2 . THR E 2 287 ? 132.057 139.194 152.151 1.00 8.44   ? 262 THR E CG2 1 
ATOM   13030 N N   . THR E 2 288 ? 128.306 138.285 149.719 1.00 14.25  ? 263 THR E N   1 
ATOM   13031 C CA  . THR E 2 288 ? 127.446 137.668 148.714 1.00 15.16  ? 263 THR E CA  1 
ATOM   13032 C C   . THR E 2 288 ? 127.072 138.690 147.651 1.00 18.61  ? 263 THR E C   1 
ATOM   13033 O O   . THR E 2 288 ? 127.149 138.411 146.450 1.00 26.07  ? 263 THR E O   1 
ATOM   13034 C CB  . THR E 2 288 ? 126.197 137.082 149.370 1.00 15.43  ? 263 THR E CB  1 
ATOM   13035 O OG1 . THR E 2 288 ? 126.584 136.124 150.361 1.00 17.46  ? 263 THR E OG1 1 
ATOM   13036 C CG2 . THR E 2 288 ? 125.330 136.397 148.331 1.00 17.94  ? 263 THR E CG2 1 
ATOM   13037 N N   . ILE E 2 289 ? 126.655 139.882 148.078 1.00 16.23  ? 264 ILE E N   1 
ATOM   13038 C CA  . ILE E 2 289 ? 126.344 140.937 147.122 1.00 18.50  ? 264 ILE E CA  1 
ATOM   13039 C C   . ILE E 2 289 ? 127.595 141.261 146.320 1.00 23.88  ? 264 ILE E C   1 
ATOM   13040 O O   . ILE E 2 289 ? 127.558 141.391 145.092 1.00 32.67  ? 264 ILE E O   1 
ATOM   13041 C CB  . ILE E 2 289 ? 125.779 142.175 147.842 1.00 15.30  ? 264 ILE E CB  1 
ATOM   13042 C CG1 . ILE E 2 289 ? 124.410 141.857 148.446 1.00 10.24  ? 264 ILE E CG1 1 
ATOM   13043 C CG2 . ILE E 2 289 ? 125.671 143.346 146.887 1.00 19.06  ? 264 ILE E CG2 1 
ATOM   13044 C CD1 . ILE E 2 289 ? 123.932 142.880 149.447 1.00 9.81   ? 264 ILE E CD1 1 
ATOM   13045 N N   . ASN E 2 290 ? 128.728 141.381 147.016 1.00 22.82  ? 265 ASN E N   1 
ATOM   13046 C CA  . ASN E 2 290 ? 129.981 141.811 146.405 1.00 24.04  ? 265 ASN E CA  1 
ATOM   13047 C C   . ASN E 2 290 ? 130.545 140.736 145.480 1.00 33.33  ? 265 ASN E C   1 
ATOM   13048 O O   . ASN E 2 290 ? 131.124 141.054 144.436 1.00 38.23  ? 265 ASN E O   1 
ATOM   13049 C CB  . ASN E 2 290 ? 130.989 142.180 147.493 1.00 21.91  ? 265 ASN E CB  1 
ATOM   13050 C CG  . ASN E 2 290 ? 132.270 142.754 146.932 1.00 25.54  ? 265 ASN E CG  1 
ATOM   13051 O OD1 . ASN E 2 290 ? 132.291 143.284 145.822 1.00 31.96  ? 265 ASN E OD1 1 
ATOM   13052 N ND2 . ASN E 2 290 ? 133.347 142.657 147.700 1.00 21.97  ? 265 ASN E ND2 1 
ATOM   13053 N N   . THR E 2 291 ? 130.384 139.457 145.842 1.00 34.81  ? 266 THR E N   1 
ATOM   13054 C CA  . THR E 2 291 ? 131.057 138.381 145.116 1.00 37.10  ? 266 THR E CA  1 
ATOM   13055 C C   . THR E 2 291 ? 130.530 138.272 143.693 1.00 44.30  ? 266 THR E C   1 
ATOM   13056 O O   . THR E 2 291 ? 131.304 138.354 142.735 1.00 55.80  ? 266 THR E O   1 
ATOM   13057 C CB  . THR E 2 291 ? 130.910 137.038 145.841 1.00 35.66  ? 266 THR E CB  1 
ATOM   13058 O OG1 . THR E 2 291 ? 129.544 136.832 146.223 1.00 40.16  ? 266 THR E OG1 1 
ATOM   13059 C CG2 . THR E 2 291 ? 131.836 136.954 147.050 1.00 30.50  ? 266 THR E CG2 1 
ATOM   13060 N N   . HIS E 2 292 ? 129.228 138.043 143.518 1.00 42.33  ? 267 HIS E N   1 
ATOM   13061 C CA  . HIS E 2 292 ? 128.790 137.835 142.143 1.00 55.18  ? 267 HIS E CA  1 
ATOM   13062 C C   . HIS E 2 292 ? 127.854 138.940 141.670 1.00 54.32  ? 267 HIS E C   1 
ATOM   13063 O O   . HIS E 2 292 ? 126.801 138.663 141.085 1.00 54.83  ? 267 HIS E O   1 
ATOM   13064 C CB  . HIS E 2 292 ? 128.143 136.455 141.970 1.00 59.29  ? 267 HIS E CB  1 
ATOM   13065 C CG  . HIS E 2 292 ? 127.226 136.046 143.082 1.00 55.46  ? 267 HIS E CG  1 
ATOM   13066 N ND1 . HIS E 2 292 ? 126.718 136.931 144.008 1.00 53.74  ? 267 HIS E ND1 1 
ATOM   13067 C CD2 . HIS E 2 292 ? 126.723 134.832 143.409 1.00 50.67  ? 267 HIS E CD2 1 
ATOM   13068 C CE1 . HIS E 2 292 ? 125.949 136.278 144.861 1.00 52.39  ? 267 HIS E CE1 1 
ATOM   13069 N NE2 . HIS E 2 292 ? 125.934 135.003 144.518 1.00 53.19  ? 267 HIS E NE2 1 
ATOM   13070 N N   . LEU E 2 293 ? 128.228 140.195 141.933 1.00 53.81  ? 268 LEU E N   1 
ATOM   13071 C CA  . LEU E 2 293 ? 127.643 141.345 141.254 1.00 63.90  ? 268 LEU E CA  1 
ATOM   13072 C C   . LEU E 2 293 ? 128.523 141.687 140.059 1.00 69.25  ? 268 LEU E C   1 
ATOM   13073 O O   . LEU E 2 293 ? 128.052 142.081 138.987 1.00 72.11  ? 268 LEU E O   1 
ATOM   13074 C CB  . LEU E 2 293 ? 127.519 142.525 142.223 1.00 60.08  ? 268 LEU E CB  1 
ATOM   13075 C CG  . LEU E 2 293 ? 126.947 143.871 141.767 1.00 49.46  ? 268 LEU E CG  1 
ATOM   13076 C CD1 . LEU E 2 293 ? 128.032 144.775 141.189 1.00 43.12  ? 268 LEU E CD1 1 
ATOM   13077 C CD2 . LEU E 2 293 ? 125.811 143.677 140.769 1.00 51.71  ? 268 LEU E CD2 1 
ATOM   13078 N N   . ARG E 2 294 ? 129.833 141.528 140.267 1.00 65.21  ? 269 ARG E N   1 
ATOM   13079 C CA  . ARG E 2 294 ? 130.906 141.910 139.357 1.00 69.23  ? 269 ARG E CA  1 
ATOM   13080 C C   . ARG E 2 294 ? 130.883 141.114 138.062 1.00 72.51  ? 269 ARG E C   1 
ATOM   13081 O O   . ARG E 2 294 ? 131.541 141.512 137.097 1.00 72.83  ? 269 ARG E O   1 
ATOM   13082 C CB  . ARG E 2 294 ? 132.246 141.754 140.071 1.00 68.23  ? 269 ARG E CB  1 
ATOM   13083 C CG  . ARG E 2 294 ? 132.334 140.459 140.834 1.00 66.58  ? 269 ARG E CG  1 
ATOM   13084 C CD  . ARG E 2 294 ? 133.606 140.332 141.640 1.00 64.43  ? 269 ARG E CD  1 
ATOM   13085 N NE  . ARG E 2 294 ? 133.650 139.054 142.341 1.00 64.88  ? 269 ARG E NE  1 
ATOM   13086 C CZ  . ARG E 2 294 ? 134.660 138.650 143.096 1.00 67.41  ? 269 ARG E CZ  1 
ATOM   13087 N NH1 . ARG E 2 294 ? 135.729 139.405 143.277 1.00 66.88  ? 269 ARG E NH1 1 
ATOM   13088 N NH2 . ARG E 2 294 ? 134.592 137.462 143.690 1.00 66.56  ? 269 ARG E NH2 1 
ATOM   13089 N N   . GLU E 2 295 ? 130.155 139.999 138.020 1.00 69.37  ? 270 GLU E N   1 
ATOM   13090 C CA  . GLU E 2 295 ? 130.014 139.250 136.780 1.00 70.39  ? 270 GLU E CA  1 
ATOM   13091 C C   . GLU E 2 295 ? 129.083 139.929 135.790 1.00 74.22  ? 270 GLU E C   1 
ATOM   13092 O O   . GLU E 2 295 ? 128.912 139.423 134.676 1.00 71.27  ? 270 GLU E O   1 
ATOM   13093 C CB  . GLU E 2 295 ? 129.475 137.847 137.075 1.00 68.40  ? 270 GLU E CB  1 
ATOM   13094 C CG  . GLU E 2 295 ? 130.172 137.129 138.211 1.00 68.26  ? 270 GLU E CG  1 
ATOM   13095 C CD  . GLU E 2 295 ? 129.386 135.931 138.706 1.00 64.30  ? 270 GLU E CD  1 
ATOM   13096 O OE1 . GLU E 2 295 ? 128.139 135.982 138.665 1.00 58.59  ? 270 GLU E OE1 1 
ATOM   13097 O OE2 . GLU E 2 295 ? 130.012 134.944 139.145 1.00 64.42  ? 270 GLU E OE2 1 
ATOM   13098 N N   . THR E 2 296 ? 128.478 141.055 136.167 1.00 78.14  ? 271 THR E N   1 
ATOM   13099 C CA  . THR E 2 296 ? 127.680 141.835 135.234 1.00 77.98  ? 271 THR E CA  1 
ATOM   13100 C C   . THR E 2 296 ? 128.562 142.716 134.353 1.00 80.45  ? 271 THR E C   1 
ATOM   13101 O O   . THR E 2 296 ? 128.081 143.271 133.359 1.00 84.49  ? 271 THR E O   1 
ATOM   13102 C CB  . THR E 2 296 ? 126.664 142.678 136.021 1.00 74.30  ? 271 THR E CB  1 
ATOM   13103 O OG1 . THR E 2 296 ? 125.880 141.814 136.853 1.00 70.83  ? 271 THR E OG1 1 
ATOM   13104 C CG2 . THR E 2 296 ? 125.709 143.424 135.093 1.00 72.90  ? 271 THR E CG2 1 
ATOM   13105 N N   . LEU E 2 297 ? 129.850 142.798 134.661 1.00 78.43  ? 272 LEU E N   1 
ATOM   13106 C CA  . LEU E 2 297 ? 130.815 143.610 133.938 1.00 76.67  ? 272 LEU E CA  1 
ATOM   13107 C C   . LEU E 2 297 ? 132.118 142.834 133.816 1.00 75.20  ? 272 LEU E C   1 
ATOM   13108 O O   . LEU E 2 297 ? 132.412 141.966 134.644 1.00 71.32  ? 272 LEU E O   1 
ATOM   13109 C CB  . LEU E 2 297 ? 131.056 144.952 134.644 1.00 68.79  ? 272 LEU E CB  1 
ATOM   13110 C CG  . LEU E 2 297 ? 131.258 144.907 136.157 1.00 67.00  ? 272 LEU E CG  1 
ATOM   13111 C CD1 . LEU E 2 297 ? 132.228 145.988 136.571 1.00 56.48  ? 272 LEU E CD1 1 
ATOM   13112 C CD2 . LEU E 2 297 ? 129.934 145.076 136.889 1.00 63.00  ? 272 LEU E CD2 1 
ATOM   13113 N N   . PRO E 2 298 ? 132.909 143.111 132.783 1.00 74.53  ? 273 PRO E N   1 
ATOM   13114 C CA  . PRO E 2 298 ? 134.200 142.428 132.627 1.00 72.07  ? 273 PRO E CA  1 
ATOM   13115 C C   . PRO E 2 298 ? 135.178 142.790 133.732 1.00 74.15  ? 273 PRO E C   1 
ATOM   13116 O O   . PRO E 2 298 ? 134.965 143.700 134.534 1.00 78.06  ? 273 PRO E O   1 
ATOM   13117 C CB  . PRO E 2 298 ? 134.726 142.953 131.290 1.00 62.81  ? 273 PRO E CB  1 
ATOM   13118 C CG  . PRO E 2 298 ? 134.036 144.259 131.112 1.00 61.55  ? 273 PRO E CG  1 
ATOM   13119 C CD  . PRO E 2 298 ? 132.690 144.123 131.738 1.00 65.33  ? 273 PRO E CD  1 
ATOM   13120 N N   . LYS E 2 299 ? 136.278 142.042 133.759 1.00 71.78  ? 274 LYS E N   1 
ATOM   13121 C CA  . LYS E 2 299 ? 137.334 142.256 134.744 1.00 65.45  ? 274 LYS E CA  1 
ATOM   13122 C C   . LYS E 2 299 ? 138.088 143.456 134.184 1.00 62.13  ? 274 LYS E C   1 
ATOM   13123 O O   . LYS E 2 299 ? 139.064 143.330 133.444 1.00 63.48  ? 274 LYS E O   1 
ATOM   13124 C CB  . LYS E 2 299 ? 138.192 141.009 134.914 1.00 69.82  ? 274 LYS E CB  1 
ATOM   13125 C CG  . LYS E 2 299 ? 139.421 141.177 135.786 1.00 70.88  ? 274 LYS E CG  1 
ATOM   13126 C CD  . LYS E 2 299 ? 140.148 139.847 135.938 1.00 71.22  ? 274 LYS E CD  1 
ATOM   13127 C CE  . LYS E 2 299 ? 140.744 139.374 134.623 1.00 67.89  ? 274 LYS E CE  1 
ATOM   13128 N NZ  . LYS E 2 299 ? 141.549 138.134 134.793 1.00 62.44  ? 274 LYS E NZ  1 
ATOM   13129 N N   . ILE E 2 300 ? 137.602 144.639 134.544 1.00 61.57  ? 275 ILE E N   1 
ATOM   13130 C CA  . ILE E 2 300 ? 138.162 145.934 134.165 1.00 65.07  ? 275 ILE E CA  1 
ATOM   13131 C C   . ILE E 2 300 ? 138.813 146.585 135.380 1.00 59.33  ? 275 ILE E C   1 
ATOM   13132 O O   . ILE E 2 300 ? 138.120 147.119 136.259 1.00 56.46  ? 275 ILE E O   1 
ATOM   13133 C CB  . ILE E 2 300 ? 137.084 146.819 133.517 1.00 64.53  ? 275 ILE E CB  1 
ATOM   13134 C CG1 . ILE E 2 300 ? 137.610 148.228 133.260 1.00 55.66  ? 275 ILE E CG1 1 
ATOM   13135 C CG2 . ILE E 2 300 ? 135.797 146.826 134.342 1.00 61.37  ? 275 ILE E CG2 1 
ATOM   13136 C CD1 . ILE E 2 300 ? 136.601 149.100 132.577 1.00 46.05  ? 275 ILE E CD1 1 
ATOM   13137 N N   . PRO E 2 301 ? 140.138 146.554 135.472 1.00 59.31  ? 276 PRO E N   1 
ATOM   13138 C CA  . PRO E 2 301 ? 140.847 147.035 136.678 1.00 56.14  ? 276 PRO E CA  1 
ATOM   13139 C C   . PRO E 2 301 ? 141.226 148.509 136.818 1.00 51.72  ? 276 PRO E C   1 
ATOM   13140 O O   . PRO E 2 301 ? 142.359 148.943 136.601 1.00 47.83  ? 276 PRO E O   1 
ATOM   13141 C CB  . PRO E 2 301 ? 142.128 146.193 136.660 1.00 62.53  ? 276 PRO E CB  1 
ATOM   13142 C CG  . PRO E 2 301 ? 141.874 145.072 135.693 1.00 69.31  ? 276 PRO E CG  1 
ATOM   13143 C CD  . PRO E 2 301 ? 140.982 145.666 134.666 1.00 66.47  ? 276 PRO E CD  1 
ATOM   13144 N N   . TYR E 2 302 ? 140.220 149.296 137.193 1.00 56.49  ? 277 TYR E N   1 
ATOM   13145 C CA  . TYR E 2 302 ? 140.430 150.593 137.820 1.00 55.13  ? 277 TYR E CA  1 
ATOM   13146 C C   . TYR E 2 302 ? 139.168 150.943 138.599 1.00 52.55  ? 277 TYR E C   1 
ATOM   13147 O O   . TYR E 2 302 ? 138.096 150.379 138.364 1.00 49.35  ? 277 TYR E O   1 
ATOM   13148 C CB  . TYR E 2 302 ? 140.786 151.701 136.814 1.00 53.98  ? 277 TYR E CB  1 
ATOM   13149 C CG  . TYR E 2 302 ? 139.737 152.066 135.778 1.00 55.46  ? 277 TYR E CG  1 
ATOM   13150 C CD1 . TYR E 2 302 ? 138.725 151.188 135.420 1.00 49.05  ? 277 TYR E CD1 1 
ATOM   13151 C CD2 . TYR E 2 302 ? 139.767 153.309 135.162 1.00 53.16  ? 277 TYR E CD2 1 
ATOM   13152 C CE1 . TYR E 2 302 ? 137.780 151.538 134.484 1.00 40.41  ? 277 TYR E CE1 1 
ATOM   13153 C CE2 . TYR E 2 302 ? 138.824 153.665 134.221 1.00 52.13  ? 277 TYR E CE2 1 
ATOM   13154 C CZ  . TYR E 2 302 ? 137.834 152.772 133.884 1.00 48.89  ? 277 TYR E CZ  1 
ATOM   13155 O OH  . TYR E 2 302 ? 136.888 153.118 132.949 1.00 48.82  ? 277 TYR E OH  1 
ATOM   13156 N N   . VAL E 2 303 ? 139.319 151.868 139.545 1.00 49.67  ? 278 VAL E N   1 
ATOM   13157 C CA  . VAL E 2 303 ? 138.295 152.100 140.556 1.00 43.97  ? 278 VAL E CA  1 
ATOM   13158 C C   . VAL E 2 303 ? 137.069 152.723 139.902 1.00 42.69  ? 278 VAL E C   1 
ATOM   13159 O O   . VAL E 2 303 ? 137.184 153.638 139.075 1.00 42.82  ? 278 VAL E O   1 
ATOM   13160 C CB  . VAL E 2 303 ? 138.844 152.994 141.681 1.00 46.93  ? 278 VAL E CB  1 
ATOM   13161 C CG1 . VAL E 2 303 ? 137.792 153.202 142.761 1.00 43.39  ? 278 VAL E CG1 1 
ATOM   13162 C CG2 . VAL E 2 303 ? 140.107 152.386 142.270 1.00 48.39  ? 278 VAL E CG2 1 
ATOM   13163 N N   . LYS E 2 304 ? 135.883 152.237 140.264 1.00 43.35  ? 279 LYS E N   1 
ATOM   13164 C CA  . LYS E 2 304 ? 134.658 152.784 139.702 1.00 39.06  ? 279 LYS E CA  1 
ATOM   13165 C C   . LYS E 2 304 ? 133.741 153.250 140.824 1.00 33.09  ? 279 LYS E C   1 
ATOM   13166 O O   . LYS E 2 304 ? 133.996 153.008 142.006 1.00 36.20  ? 279 LYS E O   1 
ATOM   13167 C CB  . LYS E 2 304 ? 133.928 151.732 138.859 1.00 32.98  ? 279 LYS E CB  1 
ATOM   13168 C CG  . LYS E 2 304 ? 134.802 151.010 137.857 1.00 37.08  ? 279 LYS E CG  1 
ATOM   13169 C CD  . LYS E 2 304 ? 134.010 149.928 137.153 1.00 36.86  ? 279 LYS E CD  1 
ATOM   13170 C CE  . LYS E 2 304 ? 133.814 148.729 138.060 1.00 44.90  ? 279 LYS E CE  1 
ATOM   13171 N NZ  . LYS E 2 304 ? 135.104 148.090 138.436 1.00 50.76  ? 279 LYS E NZ  1 
ATOM   13172 N N   . ALA E 2 305 ? 132.658 153.933 140.442 1.00 28.63  ? 280 ALA E N   1 
ATOM   13173 C CA  . ALA E 2 305 ? 131.744 154.448 141.455 1.00 27.42  ? 280 ALA E CA  1 
ATOM   13174 C C   . ALA E 2 305 ? 131.044 153.327 142.209 1.00 28.20  ? 280 ALA E C   1 
ATOM   13175 O O   . ALA E 2 305 ? 130.839 153.425 143.424 1.00 30.23  ? 280 ALA E O   1 
ATOM   13176 C CB  . ALA E 2 305 ? 130.718 155.380 140.813 1.00 25.26  ? 280 ALA E CB  1 
ATOM   13177 N N   . ILE E 2 306 ? 130.657 152.259 141.508 1.00 25.14  ? 281 ILE E N   1 
ATOM   13178 C CA  . ILE E 2 306 ? 130.009 151.143 142.187 1.00 25.10  ? 281 ILE E CA  1 
ATOM   13179 C C   . ILE E 2 306 ? 130.972 150.476 143.162 1.00 25.82  ? 281 ILE E C   1 
ATOM   13180 O O   . ILE E 2 306 ? 130.581 150.067 144.261 1.00 27.44  ? 281 ILE E O   1 
ATOM   13181 C CB  . ILE E 2 306 ? 129.433 150.147 141.161 1.00 28.54  ? 281 ILE E CB  1 
ATOM   13182 C CG1 . ILE E 2 306 ? 128.683 149.015 141.868 1.00 25.19  ? 281 ILE E CG1 1 
ATOM   13183 C CG2 . ILE E 2 306 ? 130.516 149.608 140.238 1.00 31.61  ? 281 ILE E CG2 1 
ATOM   13184 C CD1 . ILE E 2 306 ? 127.510 149.487 142.696 1.00 22.22  ? 281 ILE E CD1 1 
ATOM   13185 N N   . ASP E 2 307 ? 132.247 150.359 142.776 1.00 27.90  ? 282 ASP E N   1 
ATOM   13186 C CA  . ASP E 2 307 ? 133.236 149.751 143.660 1.00 28.47  ? 282 ASP E CA  1 
ATOM   13187 C C   . ASP E 2 307 ? 133.400 150.537 144.952 1.00 29.54  ? 282 ASP E C   1 
ATOM   13188 O O   . ASP E 2 307 ? 133.481 149.947 146.035 1.00 29.79  ? 282 ASP E O   1 
ATOM   13189 C CB  . ASP E 2 307 ? 134.576 149.615 142.940 1.00 32.58  ? 282 ASP E CB  1 
ATOM   13190 C CG  . ASP E 2 307 ? 134.474 148.795 141.673 1.00 43.10  ? 282 ASP E CG  1 
ATOM   13191 O OD1 . ASP E 2 307 ? 133.340 148.492 141.250 1.00 39.40  ? 282 ASP E OD1 1 
ATOM   13192 O OD2 . ASP E 2 307 ? 135.528 148.448 141.101 1.00 53.09  ? 282 ASP E OD2 1 
ATOM   13193 N N   . MET E 2 308 ? 133.468 151.869 144.862 1.00 29.25  ? 283 MET E N   1 
ATOM   13194 C CA  . MET E 2 308 ? 133.634 152.663 146.075 1.00 27.07  ? 283 MET E CA  1 
ATOM   13195 C C   . MET E 2 308 ? 132.447 152.496 147.010 1.00 28.06  ? 283 MET E C   1 
ATOM   13196 O O   . MET E 2 308 ? 132.620 152.387 148.230 1.00 31.95  ? 283 MET E O   1 
ATOM   13197 C CB  . MET E 2 308 ? 133.831 154.138 145.730 1.00 28.42  ? 283 MET E CB  1 
ATOM   13198 C CG  . MET E 2 308 ? 134.992 154.420 144.802 1.00 38.90  ? 283 MET E CG  1 
ATOM   13199 S SD  . MET E 2 308 ? 135.790 155.987 145.201 1.00 85.06  ? 283 MET E SD  1 
ATOM   13200 C CE  . MET E 2 308 ? 134.411 157.119 145.055 1.00 49.91  ? 283 MET E CE  1 
ATOM   13201 N N   . TYR E 2 309 ? 131.231 152.474 146.462 1.00 23.06  ? 284 TYR E N   1 
ATOM   13202 C CA  . TYR E 2 309 ? 130.062 152.363 147.323 1.00 21.03  ? 284 TYR E CA  1 
ATOM   13203 C C   . TYR E 2 309 ? 129.994 150.982 147.961 1.00 22.62  ? 284 TYR E C   1 
ATOM   13204 O O   . TYR E 2 309 ? 129.760 150.857 149.168 1.00 21.20  ? 284 TYR E O   1 
ATOM   13205 C CB  . TYR E 2 309 ? 128.794 152.662 146.525 1.00 21.81  ? 284 TYR E CB  1 
ATOM   13206 C CG  . TYR E 2 309 ? 127.595 152.963 147.391 1.00 20.81  ? 284 TYR E CG  1 
ATOM   13207 C CD1 . TYR E 2 309 ? 127.323 154.264 147.789 1.00 20.60  ? 284 TYR E CD1 1 
ATOM   13208 C CD2 . TYR E 2 309 ? 126.737 151.957 147.808 1.00 20.58  ? 284 TYR E CD2 1 
ATOM   13209 C CE1 . TYR E 2 309 ? 126.235 154.555 148.578 1.00 18.26  ? 284 TYR E CE1 1 
ATOM   13210 C CE2 . TYR E 2 309 ? 125.643 152.240 148.601 1.00 22.18  ? 284 TYR E CE2 1 
ATOM   13211 C CZ  . TYR E 2 309 ? 125.398 153.542 148.981 1.00 20.13  ? 284 TYR E CZ  1 
ATOM   13212 O OH  . TYR E 2 309 ? 124.314 153.839 149.771 1.00 22.45  ? 284 TYR E OH  1 
ATOM   13213 N N   . LEU E 2 310 ? 130.192 149.930 147.159 1.00 24.60  ? 285 LEU E N   1 
ATOM   13214 C CA  . LEU E 2 310 ? 130.146 148.578 147.704 1.00 22.00  ? 285 LEU E CA  1 
ATOM   13215 C C   . LEU E 2 310 ? 131.242 148.372 148.739 1.00 21.79  ? 285 LEU E C   1 
ATOM   13216 O O   . LEU E 2 310 ? 131.024 147.718 149.765 1.00 22.86  ? 285 LEU E O   1 
ATOM   13217 C CB  . LEU E 2 310 ? 130.262 147.551 146.579 1.00 19.17  ? 285 LEU E CB  1 
ATOM   13218 C CG  . LEU E 2 310 ? 129.120 147.538 145.563 1.00 22.44  ? 285 LEU E CG  1 
ATOM   13219 C CD1 . LEU E 2 310 ? 129.300 146.406 144.564 1.00 30.42  ? 285 LEU E CD1 1 
ATOM   13220 C CD2 . LEU E 2 310 ? 127.782 147.417 146.272 1.00 19.47  ? 285 LEU E CD2 1 
ATOM   13221 N N   . MET E 2 311 ? 132.435 148.912 148.479 1.00 20.96  ? 286 MET E N   1 
ATOM   13222 C CA  . MET E 2 311 ? 133.508 148.802 149.457 1.00 20.88  ? 286 MET E CA  1 
ATOM   13223 C C   . MET E 2 311 ? 133.294 149.756 150.619 1.00 20.26  ? 286 MET E C   1 
ATOM   13224 O O   . MET E 2 311 ? 133.727 149.471 151.740 1.00 22.50  ? 286 MET E O   1 
ATOM   13225 C CB  . MET E 2 311 ? 134.862 149.053 148.798 1.00 22.49  ? 286 MET E CB  1 
ATOM   13226 C CG  . MET E 2 311 ? 136.034 148.466 149.568 1.00 23.99  ? 286 MET E CG  1 
ATOM   13227 S SD  . MET E 2 311 ? 135.952 146.671 149.732 1.00 36.27  ? 286 MET E SD  1 
ATOM   13228 C CE  . MET E 2 311 ? 135.566 146.189 148.052 1.00 23.44  ? 286 MET E CE  1 
ATOM   13229 N N   . GLY E 2 312 ? 132.638 150.892 150.372 1.00 19.65  ? 287 GLY E N   1 
ATOM   13230 C CA  . GLY E 2 312 ? 132.249 151.756 151.471 1.00 19.24  ? 287 GLY E CA  1 
ATOM   13231 C C   . GLY E 2 312 ? 131.295 151.067 152.424 1.00 21.67  ? 287 GLY E C   1 
ATOM   13232 O O   . GLY E 2 312 ? 131.448 151.153 153.644 1.00 22.67  ? 287 GLY E O   1 
ATOM   13233 N N   . CYS E 2 313 ? 130.304 150.360 151.878 1.00 21.28  ? 288 CYS E N   1 
ATOM   13234 C CA  . CYS E 2 313 ? 129.378 149.621 152.723 1.00 19.40  ? 288 CYS E CA  1 
ATOM   13235 C C   . CYS E 2 313 ? 130.053 148.416 153.360 1.00 17.56  ? 288 CYS E C   1 
ATOM   13236 O O   . CYS E 2 313 ? 129.722 148.049 154.493 1.00 21.11  ? 288 CYS E O   1 
ATOM   13237 C CB  . CYS E 2 313 ? 128.163 149.177 151.911 1.00 16.88  ? 288 CYS E CB  1 
ATOM   13238 S SG  . CYS E 2 313 ? 127.224 150.528 151.176 1.00 18.65  ? 288 CYS E SG  1 
ATOM   13239 N N   . PHE E 2 314 ? 130.996 147.790 152.651 1.00 15.90  ? 289 PHE E N   1 
ATOM   13240 C CA  . PHE E 2 314 ? 131.721 146.665 153.228 1.00 14.55  ? 289 PHE E CA  1 
ATOM   13241 C C   . PHE E 2 314 ? 132.557 147.108 154.421 1.00 15.58  ? 289 PHE E C   1 
ATOM   13242 O O   . PHE E 2 314 ? 132.671 146.376 155.409 1.00 16.45  ? 289 PHE E O   1 
ATOM   13243 C CB  . PHE E 2 314 ? 132.596 146.000 152.165 1.00 13.21  ? 289 PHE E CB  1 
ATOM   13244 C CG  . PHE E 2 314 ? 133.278 144.748 152.637 1.00 11.32  ? 289 PHE E CG  1 
ATOM   13245 C CD1 . PHE E 2 314 ? 134.519 144.797 153.246 1.00 13.63  ? 289 PHE E CD1 1 
ATOM   13246 C CD2 . PHE E 2 314 ? 132.672 143.516 152.470 1.00 9.60   ? 289 PHE E CD2 1 
ATOM   13247 C CE1 . PHE E 2 314 ? 135.137 143.642 153.680 1.00 13.75  ? 289 PHE E CE1 1 
ATOM   13248 C CE2 . PHE E 2 314 ? 133.287 142.361 152.899 1.00 7.49   ? 289 PHE E CE2 1 
ATOM   13249 C CZ  . PHE E 2 314 ? 134.520 142.424 153.506 1.00 9.63   ? 289 PHE E CZ  1 
ATOM   13250 N N   . VAL E 2 315 ? 133.173 148.289 154.336 1.00 15.73  ? 290 VAL E N   1 
ATOM   13251 C CA  . VAL E 2 315 ? 133.956 148.791 155.461 1.00 14.89  ? 290 VAL E CA  1 
ATOM   13252 C C   . VAL E 2 315 ? 133.054 149.079 156.655 1.00 16.47  ? 290 VAL E C   1 
ATOM   13253 O O   . VAL E 2 315 ? 133.436 148.847 157.809 1.00 17.57  ? 290 VAL E O   1 
ATOM   13254 C CB  . VAL E 2 315 ? 134.766 150.031 155.042 1.00 14.38  ? 290 VAL E CB  1 
ATOM   13255 C CG1 . VAL E 2 315 ? 135.389 150.698 156.255 1.00 12.11  ? 290 VAL E CG1 1 
ATOM   13256 C CG2 . VAL E 2 315 ? 135.851 149.637 154.056 1.00 17.06  ? 290 VAL E CG2 1 
ATOM   13257 N N   . PHE E 2 316 ? 131.841 149.579 156.404 1.00 14.66  ? 291 PHE E N   1 
ATOM   13258 C CA  . PHE E 2 316 ? 130.946 149.902 157.511 1.00 13.31  ? 291 PHE E CA  1 
ATOM   13259 C C   . PHE E 2 316 ? 130.495 148.642 158.238 1.00 14.06  ? 291 PHE E C   1 
ATOM   13260 O O   . PHE E 2 316 ? 130.519 148.587 159.473 1.00 17.30  ? 291 PHE E O   1 
ATOM   13261 C CB  . PHE E 2 316 ? 129.740 150.699 157.013 1.00 15.19  ? 291 PHE E CB  1 
ATOM   13262 C CG  . PHE E 2 316 ? 129.942 152.185 157.048 1.00 18.70  ? 291 PHE E CG  1 
ATOM   13263 C CD1 . PHE E 2 316 ? 129.639 152.908 158.188 1.00 20.72  ? 291 PHE E CD1 1 
ATOM   13264 C CD2 . PHE E 2 316 ? 130.414 152.862 155.939 1.00 19.30  ? 291 PHE E CD2 1 
ATOM   13265 C CE1 . PHE E 2 316 ? 129.821 154.275 158.225 1.00 23.82  ? 291 PHE E CE1 1 
ATOM   13266 C CE2 . PHE E 2 316 ? 130.596 154.228 155.968 1.00 20.15  ? 291 PHE E CE2 1 
ATOM   13267 C CZ  . PHE E 2 316 ? 130.299 154.936 157.113 1.00 22.96  ? 291 PHE E CZ  1 
ATOM   13268 N N   . VAL E 2 317 ? 130.064 147.622 157.492 1.00 12.14  ? 292 VAL E N   1 
ATOM   13269 C CA  . VAL E 2 317 ? 129.668 146.375 158.137 1.00 10.65  ? 292 VAL E CA  1 
ATOM   13270 C C   . VAL E 2 317 ? 130.876 145.712 158.788 1.00 13.04  ? 292 VAL E C   1 
ATOM   13271 O O   . VAL E 2 317 ? 130.758 145.074 159.841 1.00 15.27  ? 292 VAL E O   1 
ATOM   13272 C CB  . VAL E 2 317 ? 128.954 145.446 157.137 1.00 9.73   ? 292 VAL E CB  1 
ATOM   13273 C CG1 . VAL E 2 317 ? 127.736 146.140 156.560 1.00 13.57  ? 292 VAL E CG1 1 
ATOM   13274 C CG2 . VAL E 2 317 ? 129.886 145.017 156.022 1.00 10.45  ? 292 VAL E CG2 1 
ATOM   13275 N N   . PHE E 2 318 ? 132.051 145.832 158.162 1.00 13.24  ? 293 PHE E N   1 
ATOM   13276 C CA  . PHE E 2 318 ? 133.275 145.347 158.789 1.00 14.02  ? 293 PHE E CA  1 
ATOM   13277 C C   . PHE E 2 318 ? 133.520 146.052 160.114 1.00 16.51  ? 293 PHE E C   1 
ATOM   13278 O O   . PHE E 2 318 ? 133.915 145.423 161.102 1.00 21.71  ? 293 PHE E O   1 
ATOM   13279 C CB  . PHE E 2 318 ? 134.464 145.545 157.847 1.00 13.81  ? 293 PHE E CB  1 
ATOM   13280 C CG  . PHE E 2 318 ? 135.803 145.370 158.509 1.00 15.63  ? 293 PHE E CG  1 
ATOM   13281 C CD1 . PHE E 2 318 ? 136.370 144.116 158.636 1.00 15.60  ? 293 PHE E CD1 1 
ATOM   13282 C CD2 . PHE E 2 318 ? 136.499 146.464 158.995 1.00 15.61  ? 293 PHE E CD2 1 
ATOM   13283 C CE1 . PHE E 2 318 ? 137.601 143.957 159.245 1.00 16.04  ? 293 PHE E CE1 1 
ATOM   13284 C CE2 . PHE E 2 318 ? 137.726 146.309 159.605 1.00 14.19  ? 293 PHE E CE2 1 
ATOM   13285 C CZ  . PHE E 2 318 ? 138.278 145.055 159.729 1.00 16.04  ? 293 PHE E CZ  1 
ATOM   13286 N N   . LEU E 2 319 ? 133.284 147.366 160.152 1.00 14.72  ? 294 LEU E N   1 
ATOM   13287 C CA  . LEU E 2 319 ? 133.524 148.135 161.366 1.00 17.57  ? 294 LEU E CA  1 
ATOM   13288 C C   . LEU E 2 319 ? 132.446 147.888 162.414 1.00 19.35  ? 294 LEU E C   1 
ATOM   13289 O O   . LEU E 2 319 ? 132.733 147.933 163.615 1.00 21.52  ? 294 LEU E O   1 
ATOM   13290 C CB  . LEU E 2 319 ? 133.617 149.622 161.029 1.00 18.19  ? 294 LEU E CB  1 
ATOM   13291 C CG  . LEU E 2 319 ? 134.595 150.455 161.858 1.00 19.15  ? 294 LEU E CG  1 
ATOM   13292 C CD1 . LEU E 2 319 ? 135.996 149.882 161.758 1.00 16.08  ? 294 LEU E CD1 1 
ATOM   13293 C CD2 . LEU E 2 319 ? 134.578 151.901 161.400 1.00 18.00  ? 294 LEU E CD2 1 
ATOM   13294 N N   . ALA E 2 320 ? 131.206 147.640 161.985 1.00 17.63  ? 295 ALA E N   1 
ATOM   13295 C CA  . ALA E 2 320 ? 130.136 147.384 162.943 1.00 16.23  ? 295 ALA E CA  1 
ATOM   13296 C C   . ALA E 2 320 ? 130.412 146.122 163.747 1.00 20.69  ? 295 ALA E C   1 
ATOM   13297 O O   . ALA E 2 320 ? 130.147 146.074 164.954 1.00 30.10  ? 295 ALA E O   1 
ATOM   13298 C CB  . ALA E 2 320 ? 128.795 147.279 162.219 1.00 15.07  ? 295 ALA E CB  1 
ATOM   13299 N N   . LEU E 2 321 ? 130.940 145.085 163.095 1.00 19.85  ? 296 LEU E N   1 
ATOM   13300 C CA  . LEU E 2 321 ? 131.324 143.880 163.820 1.00 20.94  ? 296 LEU E CA  1 
ATOM   13301 C C   . LEU E 2 321 ? 132.615 144.095 164.596 1.00 23.37  ? 296 LEU E C   1 
ATOM   13302 O O   . LEU E 2 321 ? 132.762 143.581 165.711 1.00 30.05  ? 296 LEU E O   1 
ATOM   13303 C CB  . LEU E 2 321 ? 131.463 142.705 162.852 1.00 14.58  ? 296 LEU E CB  1 
ATOM   13304 C CG  . LEU E 2 321 ? 131.965 141.388 163.442 1.00 12.49  ? 296 LEU E CG  1 
ATOM   13305 C CD1 . LEU E 2 321 ? 131.084 140.953 164.597 1.00 12.91  ? 296 LEU E CD1 1 
ATOM   13306 C CD2 . LEU E 2 321 ? 131.998 140.317 162.372 1.00 12.30  ? 296 LEU E CD2 1 
ATOM   13307 N N   . LEU E 2 322 ? 133.555 144.853 164.027 1.00 20.81  ? 297 LEU E N   1 
ATOM   13308 C CA  . LEU E 2 322 ? 134.786 145.170 164.740 1.00 21.77  ? 297 LEU E CA  1 
ATOM   13309 C C   . LEU E 2 322 ? 134.505 146.027 165.966 1.00 23.00  ? 297 LEU E C   1 
ATOM   13310 O O   . LEU E 2 322 ? 135.228 145.948 166.966 1.00 26.39  ? 297 LEU E O   1 
ATOM   13311 C CB  . LEU E 2 322 ? 135.766 145.877 163.804 1.00 23.25  ? 297 LEU E CB  1 
ATOM   13312 C CG  . LEU E 2 322 ? 137.077 146.373 164.417 1.00 24.25  ? 297 LEU E CG  1 
ATOM   13313 C CD1 . LEU E 2 322 ? 137.871 145.215 164.997 1.00 23.54  ? 297 LEU E CD1 1 
ATOM   13314 C CD2 . LEU E 2 322 ? 137.899 147.127 163.387 1.00 23.27  ? 297 LEU E CD2 1 
ATOM   13315 N N   . GLU E 2 323 ? 133.456 146.852 165.911 1.00 22.55  ? 298 GLU E N   1 
ATOM   13316 C CA  . GLU E 2 323 ? 133.129 147.699 167.052 1.00 26.37  ? 298 GLU E CA  1 
ATOM   13317 C C   . GLU E 2 323 ? 132.731 146.867 168.264 1.00 33.93  ? 298 GLU E C   1 
ATOM   13318 O O   . GLU E 2 323 ? 132.979 147.277 169.403 1.00 38.97  ? 298 GLU E O   1 
ATOM   13319 C CB  . GLU E 2 323 ? 132.026 148.689 166.664 1.00 24.04  ? 298 GLU E CB  1 
ATOM   13320 C CG  . GLU E 2 323 ? 131.488 149.566 167.791 1.00 27.87  ? 298 GLU E CG  1 
ATOM   13321 C CD  . GLU E 2 323 ? 130.244 149.004 168.455 1.00 35.89  ? 298 GLU E CD  1 
ATOM   13322 O OE1 . GLU E 2 323 ? 129.996 147.786 168.354 1.00 31.35  ? 298 GLU E OE1 1 
ATOM   13323 O OE2 . GLU E 2 323 ? 129.504 149.793 169.077 1.00 42.45  ? 298 GLU E OE2 1 
ATOM   13324 N N   . TYR E 2 324 ? 132.133 145.694 168.044 1.00 31.07  ? 299 TYR E N   1 
ATOM   13325 C CA  . TYR E 2 324 ? 131.696 144.873 169.167 1.00 31.79  ? 299 TYR E CA  1 
ATOM   13326 C C   . TYR E 2 324 ? 132.869 144.193 169.857 1.00 33.18  ? 299 TYR E C   1 
ATOM   13327 O O   . TYR E 2 324 ? 132.785 143.886 171.051 1.00 37.75  ? 299 TYR E O   1 
ATOM   13328 C CB  . TYR E 2 324 ? 130.686 143.822 168.707 1.00 31.51  ? 299 TYR E CB  1 
ATOM   13329 C CG  . TYR E 2 324 ? 130.121 143.015 169.852 1.00 35.25  ? 299 TYR E CG  1 
ATOM   13330 C CD1 . TYR E 2 324 ? 129.281 143.602 170.786 1.00 36.14  ? 299 TYR E CD1 1 
ATOM   13331 C CD2 . TYR E 2 324 ? 130.443 141.675 170.012 1.00 32.49  ? 299 TYR E CD2 1 
ATOM   13332 C CE1 . TYR E 2 324 ? 128.768 142.879 171.839 1.00 36.89  ? 299 TYR E CE1 1 
ATOM   13333 C CE2 . TYR E 2 324 ? 129.935 140.942 171.065 1.00 32.84  ? 299 TYR E CE2 1 
ATOM   13334 C CZ  . TYR E 2 324 ? 129.098 141.550 171.975 1.00 38.16  ? 299 TYR E CZ  1 
ATOM   13335 O OH  . TYR E 2 324 ? 128.585 140.832 173.028 1.00 47.26  ? 299 TYR E OH  1 
ATOM   13336 N N   . ALA E 2 325 ? 133.953 143.932 169.122 1.00 29.44  ? 300 ALA E N   1 
ATOM   13337 C CA  . ALA E 2 325 ? 135.167 143.409 169.739 1.00 29.45  ? 300 ALA E CA  1 
ATOM   13338 C C   . ALA E 2 325 ? 135.650 144.326 170.855 1.00 33.27  ? 300 ALA E C   1 
ATOM   13339 O O   . ALA E 2 325 ? 136.095 143.862 171.910 1.00 36.82  ? 300 ALA E O   1 
ATOM   13340 C CB  . ALA E 2 325 ? 136.255 143.224 168.682 1.00 23.79  ? 300 ALA E CB  1 
ATOM   13341 N N   . PHE E 2 326 ? 135.577 145.640 170.632 1.00 33.33  ? 301 PHE E N   1 
ATOM   13342 C CA  . PHE E 2 326 ? 135.935 146.588 171.681 1.00 36.63  ? 301 PHE E CA  1 
ATOM   13343 C C   . PHE E 2 326 ? 134.870 146.635 172.767 1.00 44.03  ? 301 PHE E C   1 
ATOM   13344 O O   . PHE E 2 326 ? 135.188 146.774 173.953 1.00 49.97  ? 301 PHE E O   1 
ATOM   13345 C CB  . PHE E 2 326 ? 136.156 147.974 171.079 1.00 34.48  ? 301 PHE E CB  1 
ATOM   13346 C CG  . PHE E 2 326 ? 137.381 148.071 170.219 1.00 40.19  ? 301 PHE E CG  1 
ATOM   13347 C CD1 . PHE E 2 326 ? 138.538 147.389 170.561 1.00 42.71  ? 301 PHE E CD1 1 
ATOM   13348 C CD2 . PHE E 2 326 ? 137.376 148.834 169.063 1.00 37.30  ? 301 PHE E CD2 1 
ATOM   13349 C CE1 . PHE E 2 326 ? 139.669 147.473 169.770 1.00 36.59  ? 301 PHE E CE1 1 
ATOM   13350 C CE2 . PHE E 2 326 ? 138.504 148.922 168.268 1.00 34.66  ? 301 PHE E CE2 1 
ATOM   13351 C CZ  . PHE E 2 326 ? 139.652 148.241 168.623 1.00 34.77  ? 301 PHE E CZ  1 
ATOM   13352 N N   . VAL E 2 327 ? 133.597 146.525 172.381 1.00 40.06  ? 302 VAL E N   1 
ATOM   13353 C CA  . VAL E 2 327 ? 132.510 146.552 173.358 1.00 41.85  ? 302 VAL E CA  1 
ATOM   13354 C C   . VAL E 2 327 ? 132.615 145.363 174.305 1.00 42.89  ? 302 VAL E C   1 
ATOM   13355 O O   . VAL E 2 327 ? 132.566 145.514 175.531 1.00 47.74  ? 302 VAL E O   1 
ATOM   13356 C CB  . VAL E 2 327 ? 131.147 146.582 172.644 1.00 36.78  ? 302 VAL E CB  1 
ATOM   13357 C CG1 . VAL E 2 327 ? 130.020 146.402 173.647 1.00 39.22  ? 302 VAL E CG1 1 
ATOM   13358 C CG2 . VAL E 2 327 ? 130.977 147.881 171.880 1.00 39.25  ? 302 VAL E CG2 1 
ATOM   13359 N N   . ASN E 2 328 ? 132.758 144.160 173.746 1.00 42.59  ? 303 ASN E N   1 
ATOM   13360 C CA  . ASN E 2 328 ? 132.837 142.956 174.567 1.00 45.84  ? 303 ASN E CA  1 
ATOM   13361 C C   . ASN E 2 328 ? 134.081 142.964 175.448 1.00 51.04  ? 303 ASN E C   1 
ATOM   13362 O O   . ASN E 2 328 ? 134.012 142.641 176.640 1.00 57.56  ? 303 ASN E O   1 
ATOM   13363 C CB  . ASN E 2 328 ? 132.811 141.714 173.675 1.00 39.19  ? 303 ASN E CB  1 
ATOM   13364 C CG  . ASN E 2 328 ? 132.777 140.426 174.472 1.00 47.80  ? 303 ASN E CG  1 
ATOM   13365 O OD1 . ASN E 2 328 ? 133.801 139.965 174.971 1.00 55.90  ? 303 ASN E OD1 1 
ATOM   13366 N ND2 . ASN E 2 328 ? 131.594 139.837 174.594 1.00 45.65  ? 303 ASN E ND2 1 
ATOM   13367 N N   . TYR E 2 329 ? 135.235 143.318 174.877 1.00 49.53  ? 304 TYR E N   1 
ATOM   13368 C CA  . TYR E 2 329 ? 136.478 143.294 175.643 1.00 51.75  ? 304 TYR E CA  1 
ATOM   13369 C C   . TYR E 2 329 ? 136.464 144.319 176.771 1.00 57.54  ? 304 TYR E C   1 
ATOM   13370 O O   . TYR E 2 329 ? 136.870 144.018 177.898 1.00 64.17  ? 304 TYR E O   1 
ATOM   13371 C CB  . TYR E 2 329 ? 137.677 143.530 174.726 1.00 52.81  ? 304 TYR E CB  1 
ATOM   13372 C CG  . TYR E 2 329 ? 138.993 143.592 175.472 1.00 56.18  ? 304 TYR E CG  1 
ATOM   13373 C CD1 . TYR E 2 329 ? 139.681 142.432 175.801 1.00 60.36  ? 304 TYR E CD1 1 
ATOM   13374 C CD2 . TYR E 2 329 ? 139.549 144.810 175.843 1.00 60.24  ? 304 TYR E CD2 1 
ATOM   13375 C CE1 . TYR E 2 329 ? 140.881 142.482 176.483 1.00 67.99  ? 304 TYR E CE1 1 
ATOM   13376 C CE2 . TYR E 2 329 ? 140.748 144.870 176.525 1.00 67.73  ? 304 TYR E CE2 1 
ATOM   13377 C CZ  . TYR E 2 329 ? 141.410 143.703 176.842 1.00 72.30  ? 304 TYR E CZ  1 
ATOM   13378 O OH  . TYR E 2 329 ? 142.606 143.756 177.521 1.00 72.20  ? 304 TYR E OH  1 
ATOM   13379 N N   . ILE E 2 330 ? 136.009 145.542 176.489 1.00 56.58  ? 305 ILE E N   1 
ATOM   13380 C CA  . ILE E 2 330 ? 136.095 146.612 177.477 1.00 62.61  ? 305 ILE E CA  1 
ATOM   13381 C C   . ILE E 2 330 ? 135.163 146.404 178.660 1.00 68.34  ? 305 ILE E C   1 
ATOM   13382 O O   . ILE E 2 330 ? 135.282 147.119 179.662 1.00 71.83  ? 305 ILE E O   1 
ATOM   13383 C CB  . ILE E 2 330 ? 135.811 147.980 176.822 1.00 63.81  ? 305 ILE E CB  1 
ATOM   13384 C CG1 . ILE E 2 330 ? 136.532 149.096 177.582 1.00 63.36  ? 305 ILE E CG1 1 
ATOM   13385 C CG2 . ILE E 2 330 ? 134.316 148.250 176.774 1.00 63.48  ? 305 ILE E CG2 1 
ATOM   13386 C CD1 . ILE E 2 330 ? 136.492 150.436 176.883 1.00 68.61  ? 305 ILE E CD1 1 
ATOM   13387 N N   . PHE E 2 331 ? 134.247 145.438 178.585 1.00 70.78  ? 306 PHE E N   1 
ATOM   13388 C CA  . PHE E 2 331 ? 133.483 145.032 179.761 1.00 70.43  ? 306 PHE E CA  1 
ATOM   13389 C C   . PHE E 2 331 ? 134.122 143.839 180.471 1.00 71.94  ? 306 PHE E C   1 
ATOM   13390 O O   . PHE E 2 331 ? 134.527 143.947 181.633 1.00 67.13  ? 306 PHE E O   1 
ATOM   13391 C CB  . PHE E 2 331 ? 132.037 144.709 179.359 1.00 67.16  ? 306 PHE E CB  1 
ATOM   13392 C CG  . PHE E 2 331 ? 131.157 144.304 180.512 1.00 76.47  ? 306 PHE E CG  1 
ATOM   13393 C CD1 . PHE E 2 331 ? 131.118 142.990 180.953 1.00 76.14  ? 306 PHE E CD1 1 
ATOM   13394 C CD2 . PHE E 2 331 ? 130.371 145.242 181.160 1.00 83.60  ? 306 PHE E CD2 1 
ATOM   13395 C CE1 . PHE E 2 331 ? 130.312 142.620 182.012 1.00 79.37  ? 306 PHE E CE1 1 
ATOM   13396 C CE2 . PHE E 2 331 ? 129.563 144.878 182.220 1.00 86.35  ? 306 PHE E CE2 1 
ATOM   13397 C CZ  . PHE E 2 331 ? 129.534 143.566 182.646 1.00 83.60  ? 306 PHE E CZ  1 
ATOM   13398 N N   . PHE E 2 332 ? 134.224 142.700 179.784 1.00 72.92  ? 307 PHE E N   1 
ATOM   13399 C CA  . PHE E 2 332 ? 134.707 141.492 180.444 1.00 72.08  ? 307 PHE E CA  1 
ATOM   13400 C C   . PHE E 2 332 ? 136.218 141.509 180.643 1.00 74.38  ? 307 PHE E C   1 
ATOM   13401 O O   . PHE E 2 332 ? 136.714 141.038 181.672 1.00 70.52  ? 307 PHE E O   1 
ATOM   13402 C CB  . PHE E 2 332 ? 134.304 140.256 179.637 1.00 69.94  ? 307 PHE E CB  1 
ATOM   13403 C CG  . PHE E 2 332 ? 132.818 140.073 179.492 1.00 80.30  ? 307 PHE E CG  1 
ATOM   13404 C CD1 . PHE E 2 332 ? 132.103 140.796 178.550 1.00 78.70  ? 307 PHE E CD1 1 
ATOM   13405 C CD2 . PHE E 2 332 ? 132.137 139.170 180.292 1.00 83.17  ? 307 PHE E CD2 1 
ATOM   13406 C CE1 . PHE E 2 332 ? 130.737 140.625 178.415 1.00 80.19  ? 307 PHE E CE1 1 
ATOM   13407 C CE2 . PHE E 2 332 ? 130.772 138.994 180.160 1.00 78.88  ? 307 PHE E CE2 1 
ATOM   13408 C CZ  . PHE E 2 332 ? 130.072 139.723 179.221 1.00 80.15  ? 307 PHE E CZ  1 
ATOM   13409 N N   . GLY E 2 333 ? 136.964 142.047 179.679 1.00 77.70  ? 308 GLY E N   1 
ATOM   13410 C CA  . GLY E 2 333 ? 138.407 142.135 179.802 1.00 76.22  ? 308 GLY E CA  1 
ATOM   13411 C C   . GLY E 2 333 ? 138.921 143.241 180.695 1.00 76.50  ? 308 GLY E C   1 
ATOM   13412 O O   . GLY E 2 333 ? 140.109 143.243 181.029 1.00 72.19  ? 308 GLY E O   1 
ATOM   13413 N N   . ARG E 2 334 ? 138.056 144.166 181.105 1.00 78.92  ? 309 ARG E N   1 
ATOM   13414 C CA  . ARG E 2 334 ? 138.449 145.273 181.973 1.00 79.04  ? 309 ARG E CA  1 
ATOM   13415 C C   . ARG E 2 334 ? 137.296 145.671 182.888 1.00 80.12  ? 309 ARG E C   1 
ATOM   13416 O O   . ARG E 2 334 ? 136.660 144.819 183.509 1.00 78.68  ? 309 ARG E O   1 
ATOM   13417 C CB  . ARG E 2 334 ? 138.888 146.489 181.145 1.00 72.57  ? 309 ARG E CB  1 
ATOM   13418 C CG  . ARG E 2 334 ? 140.110 146.272 180.262 1.00 71.24  ? 309 ARG E CG  1 
ATOM   13419 C CD  . ARG E 2 334 ? 140.539 147.552 179.564 1.00 74.36  ? 309 ARG E CD  1 
ATOM   13420 N NE  . ARG E 2 334 ? 141.718 147.344 178.732 1.00 71.54  ? 309 ARG E NE  1 
ATOM   13421 C CZ  . ARG E 2 334 ? 142.253 148.266 177.943 1.00 67.18  ? 309 ARG E CZ  1 
ATOM   13422 N NH1 . ARG E 2 334 ? 141.734 149.478 177.845 1.00 58.47  ? 309 ARG E NH1 1 
ATOM   13423 N NH2 . ARG E 2 334 ? 143.337 147.963 177.235 1.00 68.87  ? 309 ARG E NH2 1 
ATOM   13424 N N   . ASP E 2 444 ? 132.741 152.229 180.580 1.00 79.97  ? 444 ASP E N   1 
ATOM   13425 C CA  . ASP E 2 444 ? 132.095 152.968 179.502 1.00 72.90  ? 444 ASP E CA  1 
ATOM   13426 C C   . ASP E 2 444 ? 131.616 152.027 178.404 1.00 66.15  ? 444 ASP E C   1 
ATOM   13427 O O   . ASP E 2 444 ? 131.906 152.232 177.227 1.00 69.06  ? 444 ASP E O   1 
ATOM   13428 C CB  . ASP E 2 444 ? 133.047 154.014 178.923 1.00 79.21  ? 444 ASP E CB  1 
ATOM   13429 C CG  . ASP E 2 444 ? 133.527 155.003 179.965 1.00 83.98  ? 444 ASP E CG  1 
ATOM   13430 O OD1 . ASP E 2 444 ? 133.270 154.773 181.165 1.00 83.64  ? 444 ASP E OD1 1 
ATOM   13431 O OD2 . ASP E 2 444 ? 134.161 156.009 179.586 1.00 88.63  ? 444 ASP E OD2 1 
ATOM   13432 N N   . VAL E 2 445 ? 130.885 150.986 178.803 1.00 66.36  ? 445 VAL E N   1 
ATOM   13433 C CA  . VAL E 2 445 ? 130.278 150.087 177.827 1.00 71.47  ? 445 VAL E CA  1 
ATOM   13434 C C   . VAL E 2 445 ? 129.135 150.780 177.098 1.00 64.76  ? 445 VAL E C   1 
ATOM   13435 O O   . VAL E 2 445 ? 129.012 150.683 175.871 1.00 57.85  ? 445 VAL E O   1 
ATOM   13436 C CB  . VAL E 2 445 ? 129.807 148.796 178.519 1.00 77.89  ? 445 VAL E CB  1 
ATOM   13437 C CG1 . VAL E 2 445 ? 129.161 147.856 177.512 1.00 72.49  ? 445 VAL E CG1 1 
ATOM   13438 C CG2 . VAL E 2 445 ? 130.972 148.124 179.221 1.00 76.15  ? 445 VAL E CG2 1 
ATOM   13439 N N   . ASN E 2 446 ? 128.280 151.488 177.839 1.00 61.89  ? 446 ASN E N   1 
ATOM   13440 C CA  . ASN E 2 446 ? 127.122 152.126 177.224 1.00 57.63  ? 446 ASN E CA  1 
ATOM   13441 C C   . ASN E 2 446 ? 127.538 153.297 176.342 1.00 61.11  ? 446 ASN E C   1 
ATOM   13442 O O   . ASN E 2 446 ? 126.914 153.553 175.306 1.00 59.53  ? 446 ASN E O   1 
ATOM   13443 C CB  . ASN E 2 446 ? 126.142 152.582 178.304 1.00 52.72  ? 446 ASN E CB  1 
ATOM   13444 C CG  . ASN E 2 446 ? 124.698 152.512 177.848 1.00 42.99  ? 446 ASN E CG  1 
ATOM   13445 O OD1 . ASN E 2 446 ? 124.369 151.811 176.892 1.00 43.89  ? 446 ASN E OD1 1 
ATOM   13446 N ND2 . ASN E 2 446 ? 123.824 153.237 178.538 1.00 36.78  ? 446 ASN E ND2 1 
ATOM   13447 N N   . ALA E 2 447 ? 128.592 154.019 176.736 1.00 65.75  ? 447 ALA E N   1 
ATOM   13448 C CA  . ALA E 2 447 ? 129.031 155.176 175.960 1.00 59.96  ? 447 ALA E CA  1 
ATOM   13449 C C   . ALA E 2 447 ? 129.476 154.771 174.561 1.00 47.65  ? 447 ALA E C   1 
ATOM   13450 O O   . ALA E 2 447 ? 129.143 155.440 173.577 1.00 43.33  ? 447 ALA E O   1 
ATOM   13451 C CB  . ALA E 2 447 ? 130.158 155.904 176.691 1.00 56.10  ? 447 ALA E CB  1 
ATOM   13452 N N   . ILE E 2 448 ? 130.233 153.677 174.453 1.00 45.02  ? 448 ILE E N   1 
ATOM   13453 C CA  . ILE E 2 448 ? 130.720 153.238 173.149 1.00 46.27  ? 448 ILE E CA  1 
ATOM   13454 C C   . ILE E 2 448 ? 129.552 152.836 172.260 1.00 48.13  ? 448 ILE E C   1 
ATOM   13455 O O   . ILE E 2 448 ? 129.502 153.188 171.075 1.00 50.49  ? 448 ILE E O   1 
ATOM   13456 C CB  . ILE E 2 448 ? 131.734 152.090 173.310 1.00 50.96  ? 448 ILE E CB  1 
ATOM   13457 C CG1 . ILE E 2 448 ? 132.949 152.560 174.111 1.00 56.69  ? 448 ILE E CG1 1 
ATOM   13458 C CG2 . ILE E 2 448 ? 132.171 151.568 171.952 1.00 43.55  ? 448 ILE E CG2 1 
ATOM   13459 C CD1 . ILE E 2 448 ? 133.963 151.470 174.368 1.00 57.16  ? 448 ILE E CD1 1 
ATOM   13460 N N   . ASP E 2 449 ? 128.598 152.087 172.816 1.00 46.28  ? 449 ASP E N   1 
ATOM   13461 C CA  . ASP E 2 449 ? 127.404 151.731 172.059 1.00 42.97  ? 449 ASP E CA  1 
ATOM   13462 C C   . ASP E 2 449 ? 126.571 152.962 171.726 1.00 41.86  ? 449 ASP E C   1 
ATOM   13463 O O   . ASP E 2 449 ? 126.024 153.067 170.622 1.00 39.53  ? 449 ASP E O   1 
ATOM   13464 C CB  . ASP E 2 449 ? 126.570 150.722 172.847 1.00 44.68  ? 449 ASP E CB  1 
ATOM   13465 C CG  . ASP E 2 449 ? 126.986 149.290 172.586 1.00 47.61  ? 449 ASP E CG  1 
ATOM   13466 O OD1 . ASP E 2 449 ? 127.815 149.065 171.680 1.00 45.47  ? 449 ASP E OD1 1 
ATOM   13467 O OD2 . ASP E 2 449 ? 126.486 148.388 173.290 1.00 53.44  ? 449 ASP E OD2 1 
ATOM   13468 N N   . ARG E 2 450 ? 126.459 153.901 172.670 1.00 41.08  ? 450 ARG E N   1 
ATOM   13469 C CA  . ARG E 2 450 ? 125.646 155.094 172.443 1.00 37.89  ? 450 ARG E CA  1 
ATOM   13470 C C   . ARG E 2 450 ? 126.166 155.903 171.262 1.00 39.21  ? 450 ARG E C   1 
ATOM   13471 O O   . ARG E 2 450 ? 125.397 156.301 170.380 1.00 33.96  ? 450 ARG E O   1 
ATOM   13472 C CB  . ARG E 2 450 ? 125.609 155.959 173.702 1.00 41.30  ? 450 ARG E CB  1 
ATOM   13473 C CG  . ARG E 2 450 ? 124.666 157.144 173.588 1.00 49.41  ? 450 ARG E CG  1 
ATOM   13474 C CD  . ARG E 2 450 ? 124.654 157.987 174.852 1.00 67.22  ? 450 ARG E CD  1 
ATOM   13475 N NE  . ARG E 2 450 ? 123.771 159.139 174.712 1.00 88.38  ? 450 ARG E NE  1 
ATOM   13476 C CZ  . ARG E 2 450 ? 123.620 160.086 175.627 1.00 79.65  ? 450 ARG E CZ  1 
ATOM   13477 N NH1 . ARG E 2 450 ? 124.290 160.059 176.767 1.00 75.35  ? 450 ARG E NH1 1 
ATOM   13478 N NH2 . ARG E 2 450 ? 122.779 161.089 175.389 1.00 72.80  ? 450 ARG E NH2 1 
ATOM   13479 N N   . TRP E 2 451 ? 127.476 156.162 171.234 1.00 45.38  ? 451 TRP E N   1 
ATOM   13480 C CA  . TRP E 2 451 ? 128.045 156.966 170.157 1.00 40.51  ? 451 TRP E CA  1 
ATOM   13481 C C   . TRP E 2 451 ? 127.929 156.270 168.808 1.00 33.66  ? 451 TRP E C   1 
ATOM   13482 O O   . TRP E 2 451 ? 127.664 156.928 167.796 1.00 28.37  ? 451 TRP E O   1 
ATOM   13483 C CB  . TRP E 2 451 ? 129.504 157.303 170.464 1.00 36.11  ? 451 TRP E CB  1 
ATOM   13484 C CG  . TRP E 2 451 ? 129.653 158.471 171.386 1.00 43.26  ? 451 TRP E CG  1 
ATOM   13485 C CD1 . TRP E 2 451 ? 130.006 158.438 172.702 1.00 51.36  ? 451 TRP E CD1 1 
ATOM   13486 C CD2 . TRP E 2 451 ? 129.439 159.849 171.062 1.00 50.99  ? 451 TRP E CD2 1 
ATOM   13487 N NE1 . TRP E 2 451 ? 130.032 159.711 173.217 1.00 53.27  ? 451 TRP E NE1 1 
ATOM   13488 C CE2 . TRP E 2 451 ? 129.687 160.596 172.229 1.00 59.35  ? 451 TRP E CE2 1 
ATOM   13489 C CE3 . TRP E 2 451 ? 129.065 160.524 169.896 1.00 52.20  ? 451 TRP E CE3 1 
ATOM   13490 C CZ2 . TRP E 2 451 ? 129.573 161.983 172.265 1.00 60.56  ? 451 TRP E CZ2 1 
ATOM   13491 C CZ3 . TRP E 2 451 ? 128.952 161.902 169.934 1.00 58.53  ? 451 TRP E CZ3 1 
ATOM   13492 C CH2 . TRP E 2 451 ? 129.205 162.616 171.110 1.00 59.79  ? 451 TRP E CH2 1 
ATOM   13493 N N   . SER E 2 452 ? 128.120 154.950 168.767 1.00 33.91  ? 452 SER E N   1 
ATOM   13494 C CA  . SER E 2 452 ? 127.980 154.244 167.499 1.00 27.93  ? 452 SER E CA  1 
ATOM   13495 C C   . SER E 2 452 ? 126.561 154.352 166.959 1.00 28.01  ? 452 SER E C   1 
ATOM   13496 O O   . SER E 2 452 ? 126.361 154.315 165.739 1.00 26.88  ? 452 SER E O   1 
ATOM   13497 C CB  . SER E 2 452 ? 128.374 152.778 167.668 1.00 25.88  ? 452 SER E CB  1 
ATOM   13498 O OG  . SER E 2 452 ? 129.689 152.656 168.183 1.00 26.07  ? 452 SER E OG  1 
ATOM   13499 N N   . ARG E 2 453 ? 125.565 154.467 167.843 1.00 26.79  ? 453 ARG E N   1 
ATOM   13500 C CA  . ARG E 2 453 ? 124.190 154.641 167.390 1.00 24.77  ? 453 ARG E CA  1 
ATOM   13501 C C   . ARG E 2 453 ? 123.994 155.952 166.642 1.00 26.50  ? 453 ARG E C   1 
ATOM   13502 O O   . ARG E 2 453 ? 122.999 156.101 165.926 1.00 27.02  ? 453 ARG E O   1 
ATOM   13503 C CB  . ARG E 2 453 ? 123.225 154.581 168.574 1.00 27.31  ? 453 ARG E CB  1 
ATOM   13504 C CG  . ARG E 2 453 ? 123.130 153.226 169.249 1.00 22.84  ? 453 ARG E CG  1 
ATOM   13505 C CD  . ARG E 2 453 ? 122.301 153.315 170.518 1.00 20.13  ? 453 ARG E CD  1 
ATOM   13506 N NE  . ARG E 2 453 ? 122.322 152.075 171.284 1.00 20.31  ? 453 ARG E NE  1 
ATOM   13507 C CZ  . ARG E 2 453 ? 121.638 151.878 172.401 1.00 24.25  ? 453 ARG E CZ  1 
ATOM   13508 N NH1 . ARG E 2 453 ? 120.870 152.823 172.917 1.00 23.06  ? 453 ARG E NH1 1 
ATOM   13509 N NH2 . ARG E 2 453 ? 121.734 150.706 173.023 1.00 29.13  ? 453 ARG E NH2 1 
ATOM   13510 N N   . ILE E 2 454 ? 124.915 156.901 166.794 1.00 26.89  ? 454 ILE E N   1 
ATOM   13511 C CA  . ILE E 2 454 ? 124.858 158.185 166.107 1.00 25.61  ? 454 ILE E CA  1 
ATOM   13512 C C   . ILE E 2 454 ? 125.936 158.295 165.034 1.00 27.15  ? 454 ILE E C   1 
ATOM   13513 O O   . ILE E 2 454 ? 125.660 158.705 163.907 1.00 25.02  ? 454 ILE E O   1 
ATOM   13514 C CB  . ILE E 2 454 ? 124.957 159.355 167.112 1.00 24.41  ? 454 ILE E CB  1 
ATOM   13515 C CG1 . ILE E 2 454 ? 123.872 159.231 168.181 1.00 33.87  ? 454 ILE E CG1 1 
ATOM   13516 C CG2 . ILE E 2 454 ? 124.850 160.687 166.392 1.00 22.02  ? 454 ILE E CG2 1 
ATOM   13517 C CD1 . ILE E 2 454 ? 123.980 160.264 169.282 1.00 43.13  ? 454 ILE E CD1 1 
ATOM   13518 N N   . VAL E 2 455 ? 127.177 157.930 165.373 1.00 27.98  ? 455 VAL E N   1 
ATOM   13519 C CA  . VAL E 2 455 ? 128.294 158.124 164.450 1.00 23.11  ? 455 VAL E CA  1 
ATOM   13520 C C   . VAL E 2 455 ? 128.097 157.306 163.182 1.00 20.74  ? 455 VAL E C   1 
ATOM   13521 O O   . VAL E 2 455 ? 128.294 157.805 162.069 1.00 20.62  ? 455 VAL E O   1 
ATOM   13522 C CB  . VAL E 2 455 ? 129.628 157.785 165.139 1.00 22.73  ? 455 VAL E CB  1 
ATOM   13523 C CG1 . VAL E 2 455 ? 130.774 157.909 164.156 1.00 20.44  ? 455 VAL E CG1 1 
ATOM   13524 C CG2 . VAL E 2 455 ? 129.857 158.706 166.323 1.00 27.15  ? 455 VAL E CG2 1 
ATOM   13525 N N   . PHE E 2 456 ? 127.704 156.042 163.325 1.00 22.41  ? 456 PHE E N   1 
ATOM   13526 C CA  . PHE E 2 456 ? 127.565 155.189 162.147 1.00 22.86  ? 456 PHE E CA  1 
ATOM   13527 C C   . PHE E 2 456 ? 126.452 155.673 161.225 1.00 24.21  ? 456 PHE E C   1 
ATOM   13528 O O   . PHE E 2 456 ? 126.701 155.798 160.014 1.00 25.57  ? 456 PHE E O   1 
ATOM   13529 C CB  . PHE E 2 456 ? 127.371 153.732 162.581 1.00 21.49  ? 456 PHE E CB  1 
ATOM   13530 C CG  . PHE E 2 456 ? 128.656 153.000 162.829 1.00 22.01  ? 456 PHE E CG  1 
ATOM   13531 C CD1 . PHE E 2 456 ? 129.307 153.115 164.044 1.00 21.82  ? 456 PHE E CD1 1 
ATOM   13532 C CD2 . PHE E 2 456 ? 129.212 152.197 161.850 1.00 21.83  ? 456 PHE E CD2 1 
ATOM   13533 C CE1 . PHE E 2 456 ? 130.488 152.445 164.279 1.00 22.00  ? 456 PHE E CE1 1 
ATOM   13534 C CE2 . PHE E 2 456 ? 130.394 151.523 162.080 1.00 22.35  ? 456 PHE E CE2 1 
ATOM   13535 C CZ  . PHE E 2 456 ? 131.032 151.647 163.296 1.00 20.30  ? 456 PHE E CZ  1 
ATOM   13536 N N   . PRO E 2 457 ? 125.224 155.937 161.695 1.00 21.79  ? 457 PRO E N   1 
ATOM   13537 C CA  . PRO E 2 457 ? 124.233 156.547 160.792 1.00 20.69  ? 457 PRO E CA  1 
ATOM   13538 C C   . PRO E 2 457 ? 124.675 157.891 160.237 1.00 26.62  ? 457 PRO E C   1 
ATOM   13539 O O   . PRO E 2 457 ? 124.413 158.190 159.065 1.00 27.59  ? 457 PRO E O   1 
ATOM   13540 C CB  . PRO E 2 457 ? 122.987 156.683 161.674 1.00 20.04  ? 457 PRO E CB  1 
ATOM   13541 C CG  . PRO E 2 457 ? 123.148 155.673 162.730 1.00 22.13  ? 457 PRO E CG  1 
ATOM   13542 C CD  . PRO E 2 457 ? 124.616 155.544 162.981 1.00 22.43  ? 457 PRO E CD  1 
ATOM   13543 N N   . PHE E 2 458 ? 125.342 158.714 161.052 1.00 27.47  ? 458 PHE E N   1 
ATOM   13544 C CA  . PHE E 2 458 ? 125.762 160.037 160.596 1.00 27.73  ? 458 PHE E CA  1 
ATOM   13545 C C   . PHE E 2 458 ? 126.885 159.942 159.570 1.00 28.45  ? 458 PHE E C   1 
ATOM   13546 O O   . PHE E 2 458 ? 126.843 160.611 158.531 1.00 27.61  ? 458 PHE E O   1 
ATOM   13547 C CB  . PHE E 2 458 ? 126.188 160.888 161.795 1.00 26.16  ? 458 PHE E CB  1 
ATOM   13548 C CG  . PHE E 2 458 ? 126.791 162.212 161.424 1.00 30.61  ? 458 PHE E CG  1 
ATOM   13549 C CD1 . PHE E 2 458 ? 125.985 163.313 161.191 1.00 36.92  ? 458 PHE E CD1 1 
ATOM   13550 C CD2 . PHE E 2 458 ? 128.166 162.364 161.333 1.00 32.20  ? 458 PHE E CD2 1 
ATOM   13551 C CE1 . PHE E 2 458 ? 126.536 164.535 160.857 1.00 36.82  ? 458 PHE E CE1 1 
ATOM   13552 C CE2 . PHE E 2 458 ? 128.723 163.582 160.999 1.00 39.56  ? 458 PHE E CE2 1 
ATOM   13553 C CZ  . PHE E 2 458 ? 127.907 164.669 160.761 1.00 36.67  ? 458 PHE E CZ  1 
ATOM   13554 N N   . THR E 2 459 ? 127.904 159.123 159.845 1.00 29.08  ? 459 THR E N   1 
ATOM   13555 C CA  . THR E 2 459 ? 129.025 159.023 158.914 1.00 25.22  ? 459 THR E CA  1 
ATOM   13556 C C   . THR E 2 459 ? 128.580 158.420 157.589 1.00 23.96  ? 459 THR E C   1 
ATOM   13557 O O   . THR E 2 459 ? 129.081 158.803 156.526 1.00 26.97  ? 459 THR E O   1 
ATOM   13558 C CB  . THR E 2 459 ? 130.156 158.196 159.524 1.00 23.44  ? 459 THR E CB  1 
ATOM   13559 O OG1 . THR E 2 459 ? 130.477 158.709 160.822 1.00 28.05  ? 459 THR E OG1 1 
ATOM   13560 C CG2 . THR E 2 459 ? 131.393 158.260 158.645 1.00 19.73  ? 459 THR E CG2 1 
ATOM   13561 N N   . PHE E 2 460 ? 127.636 157.479 157.632 1.00 22.65  ? 460 PHE E N   1 
ATOM   13562 C CA  . PHE E 2 460 ? 127.160 156.871 156.396 1.00 23.12  ? 460 PHE E CA  1 
ATOM   13563 C C   . PHE E 2 460 ? 126.367 157.868 155.566 1.00 25.40  ? 460 PHE E C   1 
ATOM   13564 O O   . PHE E 2 460 ? 126.459 157.867 154.333 1.00 28.23  ? 460 PHE E O   1 
ATOM   13565 C CB  . PHE E 2 460 ? 126.315 155.636 156.705 1.00 22.32  ? 460 PHE E CB  1 
ATOM   13566 C CG  . PHE E 2 460 ? 125.940 154.841 155.488 1.00 21.10  ? 460 PHE E CG  1 
ATOM   13567 C CD1 . PHE E 2 460 ? 126.914 154.300 154.668 1.00 22.63  ? 460 PHE E CD1 1 
ATOM   13568 C CD2 . PHE E 2 460 ? 124.609 154.623 155.171 1.00 18.85  ? 460 PHE E CD2 1 
ATOM   13569 C CE1 . PHE E 2 460 ? 126.570 153.569 153.551 1.00 19.93  ? 460 PHE E CE1 1 
ATOM   13570 C CE2 . PHE E 2 460 ? 124.260 153.889 154.056 1.00 17.66  ? 460 PHE E CE2 1 
ATOM   13571 C CZ  . PHE E 2 460 ? 125.242 153.363 153.245 1.00 17.35  ? 460 PHE E CZ  1 
ATOM   13572 N N   . SER E 2 461 ? 125.576 158.723 156.219 1.00 22.20  ? 461 SER E N   1 
ATOM   13573 C CA  . SER E 2 461 ? 124.891 159.779 155.482 1.00 22.47  ? 461 SER E CA  1 
ATOM   13574 C C   . SER E 2 461 ? 125.880 160.790 154.917 1.00 27.06  ? 461 SER E C   1 
ATOM   13575 O O   . SER E 2 461 ? 125.710 161.265 153.788 1.00 29.30  ? 461 SER E O   1 
ATOM   13576 C CB  . SER E 2 461 ? 123.868 160.468 156.381 1.00 26.88  ? 461 SER E CB  1 
ATOM   13577 O OG  . SER E 2 461 ? 122.794 159.597 156.685 1.00 29.43  ? 461 SER E OG  1 
ATOM   13578 N N   . LEU E 2 462 ? 126.913 161.143 155.688 1.00 29.04  ? 462 LEU E N   1 
ATOM   13579 C CA  . LEU E 2 462 ? 127.951 162.024 155.162 1.00 28.40  ? 462 LEU E CA  1 
ATOM   13580 C C   . LEU E 2 462 ? 128.666 161.384 153.978 1.00 25.94  ? 462 LEU E C   1 
ATOM   13581 O O   . LEU E 2 462 ? 128.959 162.055 152.982 1.00 26.00  ? 462 LEU E O   1 
ATOM   13582 C CB  . LEU E 2 462 ? 128.950 162.382 156.261 1.00 27.08  ? 462 LEU E CB  1 
ATOM   13583 C CG  . LEU E 2 462 ? 130.078 163.322 155.836 1.00 25.07  ? 462 LEU E CG  1 
ATOM   13584 C CD1 . LEU E 2 462 ? 129.519 164.683 155.460 1.00 31.50  ? 462 LEU E CD1 1 
ATOM   13585 C CD2 . LEU E 2 462 ? 131.123 163.452 156.932 1.00 23.80  ? 462 LEU E CD2 1 
ATOM   13586 N N   . PHE E 2 463 ? 128.949 160.082 154.070 1.00 25.19  ? 463 PHE E N   1 
ATOM   13587 C CA  . PHE E 2 463 ? 129.549 159.370 152.948 1.00 24.37  ? 463 PHE E CA  1 
ATOM   13588 C C   . PHE E 2 463 ? 128.612 159.358 151.751 1.00 25.30  ? 463 PHE E C   1 
ATOM   13589 O O   . PHE E 2 463 ? 129.048 159.532 150.608 1.00 27.62  ? 463 PHE E O   1 
ATOM   13590 C CB  . PHE E 2 463 ? 129.919 157.947 153.371 1.00 24.58  ? 463 PHE E CB  1 
ATOM   13591 C CG  . PHE E 2 463 ? 130.136 157.006 152.222 1.00 21.98  ? 463 PHE E CG  1 
ATOM   13592 C CD1 . PHE E 2 463 ? 131.345 156.985 151.549 1.00 20.95  ? 463 PHE E CD1 1 
ATOM   13593 C CD2 . PHE E 2 463 ? 129.143 156.126 151.829 1.00 20.25  ? 463 PHE E CD2 1 
ATOM   13594 C CE1 . PHE E 2 463 ? 131.553 156.119 150.497 1.00 18.24  ? 463 PHE E CE1 1 
ATOM   13595 C CE2 . PHE E 2 463 ? 129.345 155.257 150.778 1.00 21.33  ? 463 PHE E CE2 1 
ATOM   13596 C CZ  . PHE E 2 463 ? 130.552 155.253 150.112 1.00 20.85  ? 463 PHE E CZ  1 
ATOM   13597 N N   . ASN E 2 464 ? 127.317 159.149 151.994 1.00 25.63  ? 464 ASN E N   1 
ATOM   13598 C CA  . ASN E 2 464 ? 126.353 159.138 150.901 1.00 26.84  ? 464 ASN E CA  1 
ATOM   13599 C C   . ASN E 2 464 ? 126.223 160.517 150.274 1.00 33.16  ? 464 ASN E C   1 
ATOM   13600 O O   . ASN E 2 464 ? 126.187 160.644 149.045 1.00 35.91  ? 464 ASN E O   1 
ATOM   13601 C CB  . ASN E 2 464 ? 124.994 158.646 151.395 1.00 23.02  ? 464 ASN E CB  1 
ATOM   13602 C CG  . ASN E 2 464 ? 124.932 157.143 151.519 1.00 22.91  ? 464 ASN E CG  1 
ATOM   13603 O OD1 . ASN E 2 464 ? 124.608 156.442 150.561 1.00 21.25  ? 464 ASN E OD1 1 
ATOM   13604 N ND2 . ASN E 2 464 ? 125.243 156.636 152.703 1.00 27.15  ? 464 ASN E ND2 1 
ATOM   13605 N N   . LEU E 2 465 ? 126.154 161.562 151.102 1.00 32.04  ? 465 LEU E N   1 
ATOM   13606 C CA  . LEU E 2 465 ? 126.069 162.921 150.577 1.00 32.94  ? 465 LEU E CA  1 
ATOM   13607 C C   . LEU E 2 465 ? 127.254 163.230 149.669 1.00 36.47  ? 465 LEU E C   1 
ATOM   13608 O O   . LEU E 2 465 ? 127.076 163.673 148.529 1.00 35.86  ? 465 LEU E O   1 
ATOM   13609 C CB  . LEU E 2 465 ? 125.993 163.920 151.730 1.00 33.12  ? 465 LEU E CB  1 
ATOM   13610 C CG  . LEU E 2 465 ? 125.901 165.396 151.347 1.00 41.10  ? 465 LEU E CG  1 
ATOM   13611 C CD1 . LEU E 2 465 ? 124.591 165.670 150.629 1.00 45.14  ? 465 LEU E CD1 1 
ATOM   13612 C CD2 . LEU E 2 465 ? 126.035 166.274 152.581 1.00 41.62  ? 465 LEU E CD2 1 
ATOM   13613 N N   . VAL E 2 466 ? 128.474 163.000 150.160 1.00 36.01  ? 466 VAL E N   1 
ATOM   13614 C CA  . VAL E 2 466 ? 129.664 163.284 149.361 1.00 33.40  ? 466 VAL E CA  1 
ATOM   13615 C C   . VAL E 2 466 ? 129.667 162.443 148.090 1.00 31.27  ? 466 VAL E C   1 
ATOM   13616 O O   . VAL E 2 466 ? 130.014 162.927 147.006 1.00 33.32  ? 466 VAL E O   1 
ATOM   13617 C CB  . VAL E 2 466 ? 130.936 163.049 150.197 1.00 28.23  ? 466 VAL E CB  1 
ATOM   13618 C CG1 . VAL E 2 466 ? 132.175 163.134 149.322 1.00 25.41  ? 466 VAL E CG1 1 
ATOM   13619 C CG2 . VAL E 2 466 ? 131.018 164.056 151.331 1.00 30.24  ? 466 VAL E CG2 1 
ATOM   13620 N N   . TYR E 2 467 ? 129.272 161.173 148.203 1.00 26.45  ? 467 TYR E N   1 
ATOM   13621 C CA  . TYR E 2 467 ? 129.297 160.278 147.051 1.00 25.83  ? 467 TYR E CA  1 
ATOM   13622 C C   . TYR E 2 467 ? 128.328 160.737 145.968 1.00 29.85  ? 467 TYR E C   1 
ATOM   13623 O O   . TYR E 2 467 ? 128.707 160.878 144.800 1.00 34.17  ? 467 TYR E O   1 
ATOM   13624 C CB  . TYR E 2 467 ? 128.976 158.851 147.497 1.00 21.84  ? 467 TYR E CB  1 
ATOM   13625 C CG  . TYR E 2 467 ? 128.890 157.845 146.372 1.00 21.55  ? 467 TYR E CG  1 
ATOM   13626 C CD1 . TYR E 2 467 ? 130.033 157.239 145.870 1.00 20.27  ? 467 TYR E CD1 1 
ATOM   13627 C CD2 . TYR E 2 467 ? 127.667 157.488 145.825 1.00 21.97  ? 467 TYR E CD2 1 
ATOM   13628 C CE1 . TYR E 2 467 ? 129.959 156.314 144.850 1.00 21.13  ? 467 TYR E CE1 1 
ATOM   13629 C CE2 . TYR E 2 467 ? 127.585 156.566 144.803 1.00 18.55  ? 467 TYR E CE2 1 
ATOM   13630 C CZ  . TYR E 2 467 ? 128.733 155.983 144.319 1.00 18.08  ? 467 TYR E CZ  1 
ATOM   13631 O OH  . TYR E 2 467 ? 128.653 155.063 143.301 1.00 19.38  ? 467 TYR E OH  1 
ATOM   13632 N N   . TRP E 2 468 ? 127.065 160.962 146.335 1.00 27.34  ? 468 TRP E N   1 
ATOM   13633 C CA  . TRP E 2 468 ? 126.061 161.282 145.326 1.00 31.61  ? 468 TRP E CA  1 
ATOM   13634 C C   . TRP E 2 468 ? 126.327 162.642 144.688 1.00 40.85  ? 468 TRP E C   1 
ATOM   13635 O O   . TRP E 2 468 ? 126.164 162.802 143.474 1.00 44.43  ? 468 TRP E O   1 
ATOM   13636 C CB  . TRP E 2 468 ? 124.661 161.222 145.936 1.00 26.87  ? 468 TRP E CB  1 
ATOM   13637 C CG  . TRP E 2 468 ? 124.239 159.824 146.293 1.00 27.62  ? 468 TRP E CG  1 
ATOM   13638 C CD1 . TRP E 2 468 ? 124.091 159.309 147.546 1.00 28.28  ? 468 TRP E CD1 1 
ATOM   13639 C CD2 . TRP E 2 468 ? 123.948 158.753 145.385 1.00 24.70  ? 468 TRP E CD2 1 
ATOM   13640 N NE1 . TRP E 2 468 ? 123.710 157.992 147.478 1.00 27.76  ? 468 TRP E NE1 1 
ATOM   13641 C CE2 . TRP E 2 468 ? 123.616 157.626 146.162 1.00 22.82  ? 468 TRP E CE2 1 
ATOM   13642 C CE3 . TRP E 2 468 ? 123.928 158.640 143.993 1.00 22.06  ? 468 TRP E CE3 1 
ATOM   13643 C CZ2 . TRP E 2 468 ? 123.268 156.404 145.594 1.00 18.48  ? 468 TRP E CZ2 1 
ATOM   13644 C CZ3 . TRP E 2 468 ? 123.582 157.426 143.432 1.00 20.69  ? 468 TRP E CZ3 1 
ATOM   13645 C CH2 . TRP E 2 468 ? 123.257 156.325 144.230 1.00 21.01  ? 468 TRP E CH2 1 
ATOM   13646 N N   . LEU E 2 469 ? 126.742 163.630 145.485 1.00 40.27  ? 469 LEU E N   1 
ATOM   13647 C CA  . LEU E 2 469 ? 127.101 164.932 144.927 1.00 38.79  ? 469 LEU E CA  1 
ATOM   13648 C C   . LEU E 2 469 ? 128.267 164.817 143.952 1.00 37.81  ? 469 LEU E C   1 
ATOM   13649 O O   . LEU E 2 469 ? 128.252 165.431 142.879 1.00 40.86  ? 469 LEU E O   1 
ATOM   13650 C CB  . LEU E 2 469 ? 127.426 165.924 146.043 1.00 39.57  ? 469 LEU E CB  1 
ATOM   13651 C CG  . LEU E 2 469 ? 126.265 166.289 146.971 1.00 47.66  ? 469 LEU E CG  1 
ATOM   13652 C CD1 . LEU E 2 469 ? 126.697 167.328 147.996 1.00 55.05  ? 469 LEU E CD1 1 
ATOM   13653 C CD2 . LEU E 2 469 ? 125.068 166.781 146.169 1.00 49.58  ? 469 LEU E CD2 1 
ATOM   13654 N N   . TYR E 2 470 ? 129.287 164.036 144.311 1.00 31.86  ? 470 TYR E N   1 
ATOM   13655 C CA  . TYR E 2 470 ? 130.465 163.906 143.460 1.00 31.38  ? 470 TYR E CA  1 
ATOM   13656 C C   . TYR E 2 470 ? 130.119 163.248 142.129 1.00 35.36  ? 470 TYR E C   1 
ATOM   13657 O O   . TYR E 2 470 ? 130.634 163.649 141.079 1.00 38.11  ? 470 TYR E O   1 
ATOM   13658 C CB  . TYR E 2 470 ? 131.549 163.114 144.192 1.00 29.90  ? 470 TYR E CB  1 
ATOM   13659 C CG  . TYR E 2 470 ? 132.833 162.934 143.414 1.00 36.32  ? 470 TYR E CG  1 
ATOM   13660 C CD1 . TYR E 2 470 ? 133.812 163.917 143.416 1.00 37.68  ? 470 TYR E CD1 1 
ATOM   13661 C CD2 . TYR E 2 470 ? 133.072 161.774 142.689 1.00 36.47  ? 470 TYR E CD2 1 
ATOM   13662 C CE1 . TYR E 2 470 ? 134.991 163.755 142.710 1.00 36.76  ? 470 TYR E CE1 1 
ATOM   13663 C CE2 . TYR E 2 470 ? 134.247 161.603 141.980 1.00 36.16  ? 470 TYR E CE2 1 
ATOM   13664 C CZ  . TYR E 2 470 ? 135.202 162.596 141.995 1.00 36.45  ? 470 TYR E CZ  1 
ATOM   13665 O OH  . TYR E 2 470 ? 136.372 162.430 141.291 1.00 33.44  ? 470 TYR E OH  1 
ATOM   13666 N N   . TYR E 2 471 ? 129.255 162.235 142.149 1.00 30.96  ? 471 TYR E N   1 
ATOM   13667 C CA  . TYR E 2 471 ? 128.891 161.508 140.940 1.00 32.22  ? 471 TYR E CA  1 
ATOM   13668 C C   . TYR E 2 471 ? 127.596 161.996 140.300 1.00 32.21  ? 471 TYR E C   1 
ATOM   13669 O O   . TYR E 2 471 ? 127.161 161.414 139.302 1.00 30.60  ? 471 TYR E O   1 
ATOM   13670 C CB  . TYR E 2 471 ? 128.797 160.008 141.233 1.00 28.89  ? 471 TYR E CB  1 
ATOM   13671 C CG  . TYR E 2 471 ? 130.146 159.352 141.405 1.00 26.82  ? 471 TYR E CG  1 
ATOM   13672 C CD1 . TYR E 2 471 ? 130.960 159.109 140.308 1.00 29.81  ? 471 TYR E CD1 1 
ATOM   13673 C CD2 . TYR E 2 471 ? 130.609 158.976 142.656 1.00 24.76  ? 471 TYR E CD2 1 
ATOM   13674 C CE1 . TYR E 2 471 ? 132.195 158.515 140.451 1.00 27.21  ? 471 TYR E CE1 1 
ATOM   13675 C CE2 . TYR E 2 471 ? 131.845 158.377 142.808 1.00 25.51  ? 471 TYR E CE2 1 
ATOM   13676 C CZ  . TYR E 2 471 ? 132.632 158.148 141.700 1.00 26.13  ? 471 TYR E CZ  1 
ATOM   13677 O OH  . TYR E 2 471 ? 133.864 157.552 141.837 1.00 31.51  ? 471 TYR E OH  1 
ATOM   13678 N N   . VAL E 2 472 ? 126.974 163.042 140.838 1.00 34.31  ? 472 VAL E N   1 
ATOM   13679 C CA  . VAL E 2 472 ? 125.778 163.630 140.235 1.00 39.63  ? 472 VAL E CA  1 
ATOM   13680 C C   . VAL E 2 472 ? 125.881 165.149 140.295 1.00 40.94  ? 472 VAL E C   1 
ATOM   13681 O O   . VAL E 2 472 ? 125.639 165.838 139.304 1.00 44.32  ? 472 VAL E O   1 
ATOM   13682 C CB  . VAL E 2 472 ? 124.476 163.161 140.921 1.00 44.53  ? 472 VAL E CB  1 
ATOM   13683 C CG1 . VAL E 2 472 ? 123.269 163.783 140.239 1.00 50.18  ? 472 VAL E CG1 1 
ATOM   13684 C CG2 . VAL E 2 472 ? 124.363 161.648 140.912 1.00 37.18  ? 472 VAL E CG2 1 
HETATM 13685 C C1  . NAG F 3 .   ? 126.744 125.968 98.294  1.00 64.28  ? 1   NAG a C1  1 
HETATM 13686 C C2  . NAG F 3 .   ? 127.889 126.962 98.112  1.00 70.08  ? 1   NAG a C2  1 
HETATM 13687 C C3  . NAG F 3 .   ? 128.275 127.058 96.638  1.00 72.45  ? 1   NAG a C3  1 
HETATM 13688 C C4  . NAG F 3 .   ? 128.572 125.670 96.084  1.00 74.71  ? 1   NAG a C4  1 
HETATM 13689 C C5  . NAG F 3 .   ? 127.388 124.743 96.345  1.00 68.64  ? 1   NAG a C5  1 
HETATM 13690 C C6  . NAG F 3 .   ? 127.639 123.318 95.905  1.00 69.28  ? 1   NAG a C6  1 
HETATM 13691 C C7  . NAG F 3 .   ? 127.934 128.718 99.826  1.00 62.26  ? 1   NAG a C7  1 
HETATM 13692 C C8  . NAG F 3 .   ? 127.449 130.083 100.217 1.00 61.97  ? 1   NAG a C8  1 
HETATM 13693 N N2  . NAG F 3 .   ? 127.527 128.270 98.633  1.00 68.67  ? 1   NAG a N2  1 
HETATM 13694 O O3  . NAG F 3 .   ? 129.418 127.897 96.503  1.00 69.66  ? 1   NAG a O3  1 
HETATM 13695 O O4  . NAG F 3 .   ? 128.838 125.731 94.686  1.00 74.79  ? 1   NAG a O4  1 
HETATM 13696 O O5  . NAG F 3 .   ? 127.119 124.701 97.755  1.00 64.22  ? 1   NAG a O5  1 
HETATM 13697 O O6  . NAG F 3 .   ? 126.557 122.469 96.260  1.00 63.61  ? 1   NAG a O6  1 
HETATM 13698 O O7  . NAG F 3 .   ? 128.662 128.052 100.558 1.00 56.67  ? 1   NAG a O7  1 
HETATM 13699 C C1  . NAG F 3 .   ? 130.246 125.486 94.490  1.00 104.46 ? 2   NAG a C1  1 
HETATM 13700 C C2  . NAG F 3 .   ? 130.545 125.473 92.991  1.00 103.25 ? 2   NAG a C2  1 
HETATM 13701 C C3  . NAG F 3 .   ? 132.041 125.294 92.752  1.00 104.64 ? 2   NAG a C3  1 
HETATM 13702 C C4  . NAG F 3 .   ? 132.806 126.382 93.489  1.00 110.24 ? 2   NAG a C4  1 
HETATM 13703 C C5  . NAG F 3 .   ? 132.451 126.333 94.971  1.00 109.78 ? 2   NAG a C5  1 
HETATM 13704 C C6  . NAG F 3 .   ? 133.107 127.435 95.771  1.00 104.00 ? 2   NAG a C6  1 
HETATM 13705 C C7  . NAG F 3 .   ? 128.952 124.671 91.305  1.00 102.77 ? 2   NAG a C7  1 
HETATM 13706 C C8  . NAG F 3 .   ? 128.309 123.468 90.679  1.00 91.23  ? 2   NAG a C8  1 
HETATM 13707 N N2  . NAG F 3 .   ? 129.789 124.428 92.319  1.00 97.21  ? 2   NAG a N2  1 
HETATM 13708 O O3  . NAG F 3 .   ? 132.310 125.364 91.356  1.00 98.17  ? 2   NAG a O3  1 
HETATM 13709 O O4  . NAG F 3 .   ? 134.208 126.188 93.334  1.00 108.12 ? 2   NAG a O4  1 
HETATM 13710 O O5  . NAG F 3 .   ? 131.033 126.497 95.130  1.00 109.96 ? 2   NAG a O5  1 
HETATM 13711 O O6  . NAG F 3 .   ? 132.827 127.309 97.158  1.00 102.89 ? 2   NAG a O6  1 
HETATM 13712 O O7  . NAG F 3 .   ? 128.722 125.811 90.910  1.00 109.66 ? 2   NAG a O7  1 
HETATM 13713 C C1  . BMA F 3 .   ? 134.733 127.247 92.509  1.00 53.53  ? 3   BMA a C1  1 
HETATM 13714 C C2  . BMA F 3 .   ? 136.255 127.170 92.538  1.00 53.53  ? 3   BMA a C2  1 
HETATM 13715 C C3  . BMA F 3 .   ? 136.859 128.236 91.632  1.00 53.53  ? 3   BMA a C3  1 
HETATM 13716 C C4  . BMA F 3 .   ? 136.260 128.154 90.234  1.00 53.53  ? 3   BMA a C4  1 
HETATM 13717 C C5  . BMA F 3 .   ? 134.737 128.190 90.315  1.00 53.53  ? 3   BMA a C5  1 
HETATM 13718 C C6  . BMA F 3 .   ? 134.075 127.987 88.971  1.00 53.53  ? 3   BMA a C6  1 
HETATM 13719 O O2  . BMA F 3 .   ? 136.677 125.877 92.117  1.00 53.53  ? 3   BMA a O2  1 
HETATM 13720 O O3  . BMA F 3 .   ? 138.270 128.058 91.565  1.00 53.53  ? 3   BMA a O3  1 
HETATM 13721 O O4  . BMA F 3 .   ? 136.710 129.248 89.442  1.00 53.53  ? 3   BMA a O4  1 
HETATM 13722 O O5  . BMA F 3 .   ? 134.277 127.126 91.161  1.00 53.53  ? 3   BMA a O5  1 
HETATM 13723 O O6  . BMA F 3 .   ? 134.439 126.730 88.416  1.00 53.53  ? 3   BMA a O6  1 
HETATM 13724 C C1  . MAN F 3 .   ? 138.931 129.253 92.016  1.00 118.61 ? 4   MAN a C1  1 
HETATM 13725 C C2  . MAN F 3 .   ? 139.586 129.914 90.810  1.00 117.64 ? 4   MAN a C2  1 
HETATM 13726 C C3  . MAN F 3 .   ? 140.666 129.005 90.241  1.00 119.88 ? 4   MAN a C3  1 
HETATM 13727 C C4  . MAN F 3 .   ? 141.654 128.611 91.331  1.00 117.64 ? 4   MAN a C4  1 
HETATM 13728 C C5  . MAN F 3 .   ? 140.909 128.015 92.522  1.00 116.53 ? 4   MAN a C5  1 
HETATM 13729 C C6  . MAN F 3 .   ? 141.817 127.712 93.693  1.00 108.51 ? 4   MAN a C6  1 
HETATM 13730 O O2  . MAN F 3 .   ? 140.148 131.165 91.195  1.00 107.12 ? 4   MAN a O2  1 
HETATM 13731 O O3  . MAN F 3 .   ? 141.347 129.659 89.175  1.00 114.60 ? 4   MAN a O3  1 
HETATM 13732 O O4  . MAN F 3 .   ? 142.578 127.652 90.829  1.00 110.13 ? 4   MAN a O4  1 
HETATM 13733 O O5  . MAN F 3 .   ? 139.929 128.954 92.993  1.00 124.57 ? 4   MAN a O5  1 
HETATM 13734 O O6  . MAN F 3 .   ? 141.103 127.114 94.766  1.00 107.32 ? 4   MAN a O6  1 
HETATM 13735 C C1  . MAN F 3 .   ? 133.814 126.559 87.128  1.00 25.00  ? 5   MAN a C1  1 
HETATM 13736 C C2  . MAN F 3 .   ? 133.924 125.086 86.750  1.00 25.00  ? 5   MAN a C2  1 
HETATM 13737 C C3  . MAN F 3 .   ? 135.385 124.702 86.556  1.00 25.00  ? 5   MAN a C3  1 
HETATM 13738 C C4  . MAN F 3 .   ? 136.052 125.640 85.559  1.00 25.00  ? 5   MAN a C4  1 
HETATM 13739 C C5  . MAN F 3 .   ? 135.846 127.089 85.991  1.00 25.00  ? 5   MAN a C5  1 
HETATM 13740 C C6  . MAN F 3 .   ? 136.387 128.087 84.993  1.00 25.00  ? 5   MAN a C6  1 
HETATM 13741 O O2  . MAN F 3 .   ? 133.188 124.844 85.555  1.00 25.00  ? 5   MAN a O2  1 
HETATM 13742 O O3  . MAN F 3 .   ? 135.486 123.355 86.106  1.00 25.00  ? 5   MAN a O3  1 
HETATM 13743 O O4  . MAN F 3 .   ? 137.447 125.366 85.488  1.00 25.00  ? 5   MAN a O4  1 
HETATM 13744 O O5  . MAN F 3 .   ? 134.441 127.354 86.120  1.00 25.00  ? 5   MAN a O5  1 
HETATM 13745 O O6  . MAN F 3 .   ? 135.694 128.009 83.754  1.00 25.00  ? 5   MAN a O6  1 
HETATM 13746 C C1  . NAG G 3 .   ? 110.999 108.272 117.689 1.00 59.96  ? 1   NAG b C1  1 
HETATM 13747 C C2  . NAG G 3 .   ? 111.128 106.752 117.617 1.00 60.32  ? 1   NAG b C2  1 
HETATM 13748 C C3  . NAG G 3 .   ? 110.749 106.247 116.226 1.00 66.52  ? 1   NAG b C3  1 
HETATM 13749 C C4  . NAG G 3 .   ? 109.407 106.811 115.773 1.00 70.98  ? 1   NAG b C4  1 
HETATM 13750 C C5  . NAG G 3 .   ? 109.390 108.327 115.936 1.00 65.76  ? 1   NAG b C5  1 
HETATM 13751 C C6  . NAG G 3 .   ? 108.047 108.943 115.618 1.00 63.73  ? 1   NAG b C6  1 
HETATM 13752 C C7  . NAG G 3 .   ? 112.753 105.213 118.625 1.00 59.83  ? 1   NAG b C7  1 
HETATM 13753 C C8  . NAG G 3 .   ? 114.207 104.902 118.824 1.00 54.18  ? 1   NAG b C8  1 
HETATM 13754 N N2  . NAG G 3 .   ? 112.480 106.339 117.959 1.00 58.49  ? 1   NAG b N2  1 
HETATM 13755 O O3  . NAG G 3 .   ? 110.694 104.824 116.248 1.00 70.01  ? 1   NAG b O3  1 
HETATM 13756 O O4  . NAG G 3 .   ? 109.208 106.515 114.395 1.00 74.67  ? 1   NAG b O4  1 
HETATM 13757 O O5  . NAG G 3 .   ? 109.685 108.660 117.299 1.00 63.31  ? 1   NAG b O5  1 
HETATM 13758 O O6  . NAG G 3 .   ? 108.041 110.339 115.884 1.00 60.66  ? 1   NAG b O6  1 
HETATM 13759 O O7  . NAG G 3 .   ? 111.867 104.484 119.060 1.00 66.56  ? 1   NAG b O7  1 
HETATM 13760 C C1  . NAG G 3 .   ? 108.213 105.489 114.235 1.00 73.11  ? 2   NAG b C1  1 
HETATM 13761 C C2  . NAG G 3 .   ? 107.625 105.630 112.832 1.00 72.74  ? 2   NAG b C2  1 
HETATM 13762 C C3  . NAG G 3 .   ? 106.602 104.529 112.574 1.00 79.21  ? 2   NAG b C3  1 
HETATM 13763 C C4  . NAG G 3 .   ? 107.223 103.163 112.833 1.00 82.05  ? 2   NAG b C4  1 
HETATM 13764 C C5  . NAG G 3 .   ? 107.818 103.121 114.237 1.00 77.67  ? 2   NAG b C5  1 
HETATM 13765 C C6  . NAG G 3 .   ? 108.555 101.834 114.528 1.00 76.39  ? 2   NAG b C6  1 
HETATM 13766 C C7  . NAG G 3 .   ? 107.572 107.901 111.901 1.00 76.65  ? 2   NAG b C7  1 
HETATM 13767 C C8  . NAG G 3 .   ? 106.820 109.198 111.837 1.00 67.72  ? 2   NAG b C8  1 
HETATM 13768 N N2  . NAG G 3 .   ? 107.022 106.941 112.653 1.00 75.70  ? 2   NAG b N2  1 
HETATM 13769 O O3  . NAG G 3 .   ? 106.149 104.613 111.227 1.00 81.48  ? 2   NAG b O3  1 
HETATM 13770 O O4  . NAG G 3 .   ? 106.222 102.157 112.724 1.00 89.08  ? 2   NAG b O4  1 
HETATM 13771 O O5  . NAG G 3 .   ? 108.772 104.184 114.392 1.00 75.73  ? 2   NAG b O5  1 
HETATM 13772 O O6  . NAG G 3 .   ? 109.162 101.863 115.812 1.00 77.18  ? 2   NAG b O6  1 
HETATM 13773 O O7  . NAG G 3 .   ? 108.629 107.732 111.301 1.00 80.70  ? 2   NAG b O7  1 
HETATM 13774 C C1  . BMA G 3 .   ? 106.476 101.334 111.566 1.00 88.86  ? 3   BMA b C1  1 
HETATM 13775 C C2  . BMA G 3 .   ? 105.425 100.230 111.536 1.00 89.76  ? 3   BMA b C2  1 
HETATM 13776 C C3  . BMA G 3 .   ? 105.620 99.351  110.309 1.00 94.63  ? 3   BMA b C3  1 
HETATM 13777 C C4  . BMA G 3 .   ? 105.629 100.200 109.047 1.00 94.82  ? 3   BMA b C4  1 
HETATM 13778 C C5  . BMA G 3 .   ? 106.669 101.310 109.173 1.00 90.09  ? 3   BMA b C5  1 
HETATM 13779 C C6  . BMA G 3 .   ? 106.654 102.268 108.004 1.00 85.33  ? 3   BMA b C6  1 
HETATM 13780 O O2  . BMA G 3 .   ? 104.125 100.811 111.519 1.00 86.94  ? 3   BMA b O2  1 
HETATM 13781 O O3  . BMA G 3 .   ? 104.584 98.377  110.231 1.00 92.56  ? 3   BMA b O3  1 
HETATM 13782 O O4  . BMA G 3 .   ? 105.943 99.392  107.917 1.00 93.62  ? 3   BMA b O4  1 
HETATM 13783 O O5  . BMA G 3 .   ? 106.410 102.090 110.353 1.00 91.77  ? 3   BMA b O5  1 
HETATM 13784 O O6  . BMA G 3 .   ? 105.388 102.899 107.863 1.00 89.32  ? 3   BMA b O6  1 
HETATM 13785 C C1  . MAN G 3 .   ? 104.797 97.374  111.243 1.00 49.53  ? 4   MAN b C1  1 
HETATM 13786 C C2  . MAN G 3 .   ? 104.777 96.002  110.578 1.00 49.53  ? 4   MAN b C2  1 
HETATM 13787 C C3  . MAN G 3 .   ? 103.400 95.727  109.987 1.00 49.53  ? 4   MAN b C3  1 
HETATM 13788 C C4  . MAN G 3 .   ? 102.319 95.918  111.044 1.00 49.53  ? 4   MAN b C4  1 
HETATM 13789 C C5  . MAN G 3 .   ? 102.459 97.292  111.693 1.00 49.53  ? 4   MAN b C5  1 
HETATM 13790 C C6  . MAN G 3 .   ? 101.490 97.510  112.833 1.00 49.53  ? 4   MAN b C6  1 
HETATM 13791 O O2  . MAN G 3 .   ? 105.108 95.001  111.535 1.00 49.53  ? 4   MAN b O2  1 
HETATM 13792 O O3  . MAN G 3 .   ? 103.348 94.403  109.464 1.00 49.53  ? 4   MAN b O3  1 
HETATM 13793 O O4  . MAN G 3 .   ? 101.030 95.812  110.448 1.00 49.53  ? 4   MAN b O4  1 
HETATM 13794 O O5  . MAN G 3 .   ? 103.779 97.429  112.242 1.00 49.53  ? 4   MAN b O5  1 
HETATM 13795 O O6  . MAN G 3 .   ? 101.630 98.809  113.390 1.00 49.53  ? 4   MAN b O6  1 
HETATM 13796 C C1  . MAN G 3 .   ? 105.387 103.644 106.626 1.00 90.32  ? 5   MAN b C1  1 
HETATM 13797 C C2  . MAN G 3 .   ? 104.272 104.683 106.682 1.00 92.37  ? 5   MAN b C2  1 
HETATM 13798 C C3  . MAN G 3 .   ? 102.919 103.989 106.757 1.00 95.81  ? 5   MAN b C3  1 
HETATM 13799 C C4  . MAN G 3 .   ? 102.768 103.008 105.603 1.00 99.80  ? 5   MAN b C4  1 
HETATM 13800 C C5  . MAN G 3 .   ? 103.949 102.042 105.584 1.00 99.50  ? 5   MAN b C5  1 
HETATM 13801 C C6  . MAN G 3 .   ? 103.927 101.105 104.398 1.00 93.68  ? 5   MAN b C6  1 
HETATM 13802 O O2  . MAN G 3 .   ? 104.334 105.519 105.531 1.00 86.16  ? 5   MAN b O2  1 
HETATM 13803 O O3  . MAN G 3 .   ? 101.872 104.953 106.717 1.00 90.54  ? 5   MAN b O3  1 
HETATM 13804 O O4  . MAN G 3 .   ? 101.561 102.265 105.746 1.00 96.06  ? 5   MAN b O4  1 
HETATM 13805 O O5  . MAN G 3 .   ? 105.175 102.787 105.500 1.00 94.25  ? 5   MAN b O5  1 
HETATM 13806 O O6  . MAN G 3 .   ? 105.065 100.254 104.384 1.00 89.14  ? 5   MAN b O6  1 
HETATM 13807 C C1  . NAG H 4 .   ? 134.890 97.571  93.190  1.00 62.75  ? 1   NAG F C1  1 
HETATM 13808 C C2  . NAG H 4 .   ? 135.837 96.467  93.657  1.00 65.92  ? 1   NAG F C2  1 
HETATM 13809 C C3  . NAG H 4 .   ? 135.149 95.110  93.562  1.00 66.95  ? 1   NAG F C3  1 
HETATM 13810 C C4  . NAG H 4 .   ? 133.836 95.138  94.332  1.00 67.39  ? 1   NAG F C4  1 
HETATM 13811 C C5  . NAG H 4 .   ? 132.968 96.291  93.837  1.00 60.88  ? 1   NAG F C5  1 
HETATM 13812 C C6  . NAG H 4 .   ? 131.690 96.451  94.628  1.00 59.60  ? 1   NAG F C6  1 
HETATM 13813 C C7  . NAG H 4 .   ? 138.276 96.327  93.427  1.00 68.75  ? 1   NAG F C7  1 
HETATM 13814 C C8  . NAG H 4 .   ? 139.433 96.307  92.471  1.00 65.37  ? 1   NAG F C8  1 
HETATM 13815 N N2  . NAG H 4 .   ? 137.065 96.477  92.879  1.00 69.13  ? 1   NAG F N2  1 
HETATM 13816 O O3  . NAG H 4 .   ? 136.007 94.106  94.094  1.00 69.41  ? 1   NAG F O3  1 
HETATM 13817 O O4  . NAG H 4 .   ? 133.134 93.916  94.123  1.00 66.73  ? 1   NAG F O4  1 
HETATM 13818 O O5  . NAG H 4 .   ? 133.688 97.529  93.961  1.00 60.19  ? 1   NAG F O5  1 
HETATM 13819 O O6  . NAG H 4 .   ? 130.912 97.535  94.141  1.00 56.68  ? 1   NAG F O6  1 
HETATM 13820 O O7  . NAG H 4 .   ? 138.433 96.214  94.639  1.00 69.16  ? 1   NAG F O7  1 
HETATM 13821 C C1  . NAG H 4 .   ? 133.153 93.123  95.326  1.00 54.10  ? 2   NAG F C1  1 
HETATM 13822 C C2  . NAG H 4 .   ? 131.852 92.325  95.377  1.00 54.10  ? 2   NAG F C2  1 
HETATM 13823 C C3  . NAG H 4 .   ? 131.830 91.435  96.616  1.00 54.10  ? 2   NAG F C3  1 
HETATM 13824 C C4  . NAG H 4 .   ? 133.077 90.561  96.647  1.00 54.10  ? 2   NAG F C4  1 
HETATM 13825 C C5  . NAG H 4 .   ? 134.327 91.432  96.546  1.00 54.10  ? 2   NAG F C5  1 
HETATM 13826 C C6  . NAG H 4 .   ? 135.603 90.625  96.462  1.00 54.10  ? 2   NAG F C6  1 
HETATM 13827 C C7  . NAG H 4 .   ? 129.824 93.243  94.345  1.00 54.10  ? 2   NAG F C7  1 
HETATM 13828 C C8  . NAG H 4 .   ? 128.704 94.234  94.474  1.00 54.10  ? 2   NAG F C8  1 
HETATM 13829 N N2  . NAG H 4 .   ? 130.700 93.211  95.357  1.00 54.10  ? 2   NAG F N2  1 
HETATM 13830 O O3  . NAG H 4 .   ? 130.662 90.622  96.600  1.00 54.10  ? 2   NAG F O3  1 
HETATM 13831 O O4  . NAG H 4 .   ? 133.121 89.814  97.858  1.00 54.10  ? 2   NAG F O4  1 
HETATM 13832 O O5  . NAG H 4 .   ? 134.265 92.227  95.351  1.00 54.10  ? 2   NAG F O5  1 
HETATM 13833 O O6  . NAG H 4 .   ? 135.773 89.796  97.604  1.00 54.10  ? 2   NAG F O6  1 
HETATM 13834 O O7  . NAG H 4 .   ? 129.933 92.508  93.367  1.00 54.10  ? 2   NAG F O7  1 
HETATM 13835 C C1  . NAG I 3 .   ? 160.141 139.132 124.610 1.00 52.49  ? 1   NAG c C1  1 
HETATM 13836 C C2  . NAG I 3 .   ? 160.940 140.432 124.566 1.00 52.61  ? 1   NAG c C2  1 
HETATM 13837 C C3  . NAG I 3 .   ? 161.814 140.478 123.314 1.00 53.04  ? 1   NAG c C3  1 
HETATM 13838 C C4  . NAG I 3 .   ? 162.641 139.204 123.166 1.00 58.54  ? 1   NAG c C4  1 
HETATM 13839 C C5  . NAG I 3 .   ? 161.759 137.966 123.303 1.00 61.87  ? 1   NAG c C5  1 
HETATM 13840 C C6  . NAG I 3 .   ? 162.548 136.677 123.319 1.00 67.47  ? 1   NAG c C6  1 
HETATM 13841 C C7  . NAG I 3 .   ? 160.345 142.689 125.318 1.00 55.23  ? 1   NAG c C7  1 
HETATM 13842 C C8  . NAG I 3 .   ? 159.343 143.803 125.232 1.00 46.92  ? 1   NAG c C8  1 
HETATM 13843 N N2  . NAG I 3 .   ? 160.059 141.587 124.617 1.00 50.88  ? 1   NAG c N2  1 
HETATM 13844 O O3  . NAG I 3 .   ? 162.672 141.612 123.378 1.00 54.65  ? 1   NAG c O3  1 
HETATM 13845 O O4  . NAG I 3 .   ? 163.260 139.178 121.885 1.00 64.12  ? 1   NAG c O4  1 
HETATM 13846 O O5  . NAG I 3 .   ? 161.032 138.023 124.539 1.00 62.66  ? 1   NAG c O5  1 
HETATM 13847 O O6  . NAG I 3 .   ? 161.693 135.547 123.418 1.00 76.80  ? 1   NAG c O6  1 
HETATM 13848 O O7  . NAG I 3 .   ? 161.366 142.784 125.992 1.00 61.37  ? 1   NAG c O7  1 
HETATM 13849 C C1  . NAG I 3 .   ? 164.687 139.314 122.009 1.00 66.05  ? 2   NAG c C1  1 
HETATM 13850 C C2  . NAG I 3 .   ? 165.334 138.552 120.853 1.00 71.72  ? 2   NAG c C2  1 
HETATM 13851 C C3  . NAG I 3 .   ? 166.849 138.732 120.879 1.00 71.46  ? 2   NAG c C3  1 
HETATM 13852 C C4  . NAG I 3 .   ? 167.202 140.212 120.901 1.00 69.21  ? 2   NAG c C4  1 
HETATM 13853 C C5  . NAG I 3 .   ? 166.500 140.887 122.075 1.00 60.65  ? 2   NAG c C5  1 
HETATM 13854 C C6  . NAG I 3 .   ? 166.719 142.382 122.124 1.00 60.82  ? 2   NAG c C6  1 
HETATM 13855 C C7  . NAG I 3 .   ? 164.102 136.579 120.070 1.00 79.46  ? 2   NAG c C7  1 
HETATM 13856 C C8  . NAG I 3 .   ? 163.917 135.097 120.210 1.00 78.86  ? 2   NAG c C8  1 
HETATM 13857 N N2  . NAG I 3 .   ? 164.985 137.142 120.902 1.00 78.56  ? 2   NAG c N2  1 
HETATM 13858 O O3  . NAG I 3 .   ? 167.418 138.113 119.730 1.00 72.29  ? 2   NAG c O3  1 
HETATM 13859 O O4  . NAG I 3 .   ? 168.612 140.372 121.022 1.00 77.90  ? 2   NAG c O4  1 
HETATM 13860 O O5  . NAG I 3 .   ? 165.083 140.685 121.963 1.00 62.00  ? 2   NAG c O5  1 
HETATM 13861 O O6  . NAG I 3 .   ? 166.133 142.953 123.284 1.00 64.08  ? 2   NAG c O6  1 
HETATM 13862 O O7  . NAG I 3 .   ? 163.481 137.236 119.239 1.00 75.26  ? 2   NAG c O7  1 
HETATM 13863 C C1  . BMA I 3 .   ? 169.112 141.077 119.862 1.00 83.72  ? 3   BMA c C1  1 
HETATM 13864 C C2  . BMA I 3 .   ? 170.559 141.471 120.142 1.00 90.61  ? 3   BMA c C2  1 
HETATM 13865 C C3  . BMA I 3 .   ? 171.148 142.196 118.941 1.00 91.99  ? 3   BMA c C3  1 
HETATM 13866 C C4  . BMA I 3 .   ? 170.989 141.356 117.683 1.00 90.61  ? 3   BMA c C4  1 
HETATM 13867 C C5  . BMA I 3 .   ? 169.527 140.957 117.503 1.00 86.19  ? 3   BMA c C5  1 
HETATM 13868 C C6  . BMA I 3 .   ? 169.313 140.020 116.335 1.00 88.88  ? 3   BMA c C6  1 
HETATM 13869 O O2  . BMA I 3 .   ? 171.323 140.302 120.425 1.00 87.44  ? 3   BMA c O2  1 
HETATM 13870 O O3  . BMA I 3 .   ? 172.524 142.479 119.169 1.00 90.08  ? 3   BMA c O3  1 
HETATM 13871 O O4  . BMA I 3 .   ? 171.417 142.096 116.545 1.00 93.59  ? 3   BMA c O4  1 
HETATM 13872 O O5  . BMA I 3 .   ? 169.058 140.275 118.678 1.00 84.49  ? 3   BMA c O5  1 
HETATM 13873 O O6  . BMA I 3 .   ? 170.100 138.843 116.462 1.00 96.72  ? 3   BMA c O6  1 
HETATM 13874 C C1  . MAN I 3 .   ? 172.666 143.881 119.463 1.00 10.85  ? 4   MAN c C1  1 
HETATM 13875 C C2  . MAN I 3 .   ? 173.688 144.467 118.496 1.00 10.85  ? 4   MAN c C2  1 
HETATM 13876 C C3  . MAN I 3 .   ? 175.055 143.840 118.738 1.00 10.85  ? 4   MAN c C3  1 
HETATM 13877 C C4  . MAN I 3 .   ? 175.450 143.982 120.201 1.00 10.85  ? 4   MAN c C4  1 
HETATM 13878 C C5  . MAN I 3 .   ? 174.348 143.416 121.093 1.00 10.85  ? 4   MAN c C5  1 
HETATM 13879 C C6  . MAN I 3 .   ? 174.617 143.618 122.567 1.00 10.85  ? 4   MAN c C6  1 
HETATM 13880 O O2  . MAN I 3 .   ? 173.757 145.879 118.670 1.00 10.85  ? 4   MAN c O2  1 
HETATM 13881 O O3  . MAN I 3 .   ? 176.030 144.458 117.904 1.00 10.85  ? 4   MAN c O3  1 
HETATM 13882 O O4  . MAN I 3 .   ? 176.661 143.277 120.451 1.00 10.85  ? 4   MAN c O4  1 
HETATM 13883 O O5  . MAN I 3 .   ? 173.109 144.085 120.805 1.00 10.85  ? 4   MAN c O5  1 
HETATM 13884 O O6  . MAN I 3 .   ? 173.589 143.047 123.365 1.00 10.85  ? 4   MAN c O6  1 
HETATM 13885 C C1  . MAN I 3 .   ? 170.307 138.279 115.149 1.00 95.07  ? 5   MAN c C1  1 
HETATM 13886 C C2  . MAN I 3 .   ? 170.726 136.821 115.313 1.00 94.49  ? 5   MAN c C2  1 
HETATM 13887 C C3  . MAN I 3 .   ? 172.067 136.745 116.030 1.00 98.52  ? 5   MAN c C3  1 
HETATM 13888 C C4  . MAN I 3 .   ? 173.103 137.589 115.300 1.00 102.59 ? 5   MAN c C4  1 
HETATM 13889 C C5  . MAN I 3 .   ? 172.582 139.012 115.119 1.00 101.78 ? 5   MAN c C5  1 
HETATM 13890 C C6  . MAN I 3 .   ? 173.507 139.879 114.295 1.00 96.83  ? 5   MAN c C6  1 
HETATM 13891 O O2  . MAN I 3 .   ? 170.819 136.204 114.034 1.00 86.36  ? 5   MAN c O2  1 
HETATM 13892 O O3  . MAN I 3 .   ? 172.503 135.392 116.110 1.00 98.35  ? 5   MAN c O3  1 
HETATM 13893 O O4  . MAN I 3 .   ? 174.316 137.626 116.045 1.00 100.88 ? 5   MAN c O4  1 
HETATM 13894 O O5  . MAN I 3 .   ? 171.323 138.980 114.428 1.00 95.14  ? 5   MAN c O5  1 
HETATM 13895 O O6  . MAN I 3 .   ? 172.998 141.199 114.162 1.00 94.16  ? 5   MAN c O6  1 
HETATM 13896 C C1  . NAG J 4 .   ? 154.969 160.780 96.183  1.00 97.22  ? 1   NAG G C1  1 
HETATM 13897 C C2  . NAG J 4 .   ? 154.888 162.139 96.877  1.00 104.18 ? 1   NAG G C2  1 
HETATM 13898 C C3  . NAG J 4 .   ? 156.246 162.835 96.832  1.00 108.62 ? 1   NAG G C3  1 
HETATM 13899 C C4  . NAG J 4 .   ? 157.321 161.921 97.405  1.00 106.29 ? 1   NAG G C4  1 
HETATM 13900 C C5  . NAG J 4 .   ? 157.301 160.583 96.674  1.00 101.22 ? 1   NAG G C5  1 
HETATM 13901 C C6  . NAG J 4 .   ? 158.280 159.580 97.242  1.00 106.00 ? 1   NAG G C6  1 
HETATM 13902 C C7  . NAG J 4 .   ? 153.204 163.926 96.926  1.00 107.96 ? 1   NAG G C7  1 
HETATM 13903 C C8  . NAG J 4 .   ? 152.163 164.672 96.143  1.00 101.52 ? 1   NAG G C8  1 
HETATM 13904 N N2  . NAG J 4 .   ? 153.864 162.970 96.263  1.00 105.30 ? 1   NAG G N2  1 
HETATM 13905 O O3  . NAG J 4 .   ? 156.184 164.048 97.576  1.00 108.97 ? 1   NAG G O3  1 
HETATM 13906 O O4  . NAG J 4 .   ? 158.603 162.517 97.231  1.00 104.00 ? 1   NAG G O4  1 
HETATM 13907 O O5  . NAG J 4 .   ? 155.996 159.993 96.787  1.00 99.75  ? 1   NAG G O5  1 
HETATM 13908 O O6  . NAG J 4 .   ? 158.269 158.369 96.499  1.00 105.20 ? 1   NAG G O6  1 
HETATM 13909 O O7  . NAG J 4 .   ? 153.438 164.180 98.105  1.00 110.13 ? 1   NAG G O7  1 
HETATM 13910 C C1  . NAG J 4 .   ? 159.108 162.970 98.504  1.00 40.76  ? 2   NAG G C1  1 
HETATM 13911 C C2  . NAG J 4 .   ? 160.631 163.080 98.432  1.00 40.76  ? 2   NAG G C2  1 
HETATM 13912 C C3  . NAG J 4 .   ? 161.182 163.613 99.752  1.00 40.76  ? 2   NAG G C3  1 
HETATM 13913 C C4  . NAG J 4 .   ? 160.495 164.922 100.114 1.00 40.76  ? 2   NAG G C4  1 
HETATM 13914 C C5  . NAG J 4 .   ? 158.981 164.732 100.119 1.00 40.76  ? 2   NAG G C5  1 
HETATM 13915 C C6  . NAG J 4 .   ? 158.224 166.017 100.371 1.00 40.76  ? 2   NAG G C6  1 
HETATM 13916 C C7  . NAG J 4 .   ? 161.262 161.296 96.866  1.00 40.76  ? 2   NAG G C7  1 
HETATM 13917 C C8  . NAG J 4 .   ? 161.919 159.954 96.714  1.00 40.76  ? 2   NAG G C8  1 
HETATM 13918 N N2  . NAG J 4 .   ? 161.237 161.800 98.105  1.00 40.76  ? 2   NAG G N2  1 
HETATM 13919 O O3  . NAG J 4 .   ? 162.587 163.813 99.635  1.00 40.76  ? 2   NAG G O3  1 
HETATM 13920 O O4  . NAG J 4 .   ? 160.916 165.356 101.404 1.00 40.76  ? 2   NAG G O4  1 
HETATM 13921 O O5  . NAG J 4 .   ? 158.552 164.243 98.839  1.00 40.76  ? 2   NAG G O5  1 
HETATM 13922 O O6  . NAG J 4 .   ? 158.579 166.589 101.623 1.00 40.76  ? 2   NAG G O6  1 
HETATM 13923 O O7  . NAG J 4 .   ? 160.775 161.893 95.910  1.00 40.76  ? 2   NAG G O7  1 
HETATM 13924 C C1  . NAG K 3 .   ? 142.176 133.757 101.722 1.00 58.32  ? 1   NAG d C1  1 
HETATM 13925 C C2  . NAG K 3 .   ? 141.793 134.363 100.375 1.00 62.29  ? 1   NAG d C2  1 
HETATM 13926 C C3  . NAG K 3 .   ? 140.581 135.277 100.528 1.00 71.62  ? 1   NAG d C3  1 
HETATM 13927 C C4  . NAG K 3 .   ? 139.445 134.524 101.212 1.00 75.63  ? 1   NAG d C4  1 
HETATM 13928 C C5  . NAG K 3 .   ? 139.928 133.909 102.524 1.00 71.60  ? 1   NAG d C5  1 
HETATM 13929 C C6  . NAG K 3 .   ? 138.885 133.045 103.197 1.00 73.33  ? 1   NAG d C6  1 
HETATM 13930 C C7  . NAG K 3 .   ? 143.469 134.737 98.624  1.00 59.81  ? 1   NAG d C7  1 
HETATM 13931 C C8  . NAG K 3 .   ? 144.614 135.590 98.163  1.00 55.04  ? 1   NAG d C8  1 
HETATM 13932 N N2  . NAG K 3 .   ? 142.911 135.084 99.789  1.00 61.67  ? 1   NAG d N2  1 
HETATM 13933 O O3  . NAG K 3 .   ? 140.163 135.738 99.247  1.00 71.43  ? 1   NAG d O3  1 
HETATM 13934 O O4  . NAG K 3 .   ? 138.313 135.365 101.416 1.00 77.45  ? 1   NAG d O4  1 
HETATM 13935 O O5  . NAG K 3 .   ? 141.059 133.063 102.266 1.00 57.77  ? 1   NAG d O5  1 
HETATM 13936 O O6  . NAG K 3 .   ? 139.404 132.418 104.362 1.00 76.00  ? 1   NAG d O6  1 
HETATM 13937 O O7  . NAG K 3 .   ? 143.066 133.779 97.970  1.00 60.10  ? 1   NAG d O7  1 
HETATM 13938 C C1  . NAG K 3 .   ? 137.259 134.841 100.573 1.00 32.90  ? 2   NAG d C1  1 
HETATM 13939 C C2  . NAG K 3 .   ? 136.003 135.692 100.752 1.00 32.90  ? 2   NAG d C2  1 
HETATM 13940 C C3  . NAG K 3 .   ? 134.889 135.183 99.842  1.00 32.90  ? 2   NAG d C3  1 
HETATM 13941 C C4  . NAG K 3 .   ? 135.379 135.134 98.400  1.00 32.90  ? 2   NAG d C4  1 
HETATM 13942 C C5  . NAG K 3 .   ? 136.656 134.304 98.314  1.00 32.90  ? 2   NAG d C5  1 
HETATM 13943 C C6  . NAG K 3 .   ? 137.261 134.292 96.928  1.00 32.90  ? 2   NAG d C6  1 
HETATM 13944 C C7  . NAG K 3 .   ? 135.594 136.780 102.914 1.00 32.90  ? 2   NAG d C7  1 
HETATM 13945 C C8  . NAG K 3 .   ? 135.101 136.601 104.320 1.00 32.90  ? 2   NAG d C8  1 
HETATM 13946 N N2  . NAG K 3 .   ? 135.573 135.688 102.141 1.00 32.90  ? 2   NAG d N2  1 
HETATM 13947 O O3  . NAG K 3 .   ? 133.763 136.048 99.948  1.00 32.90  ? 2   NAG d O3  1 
HETATM 13948 O O4  . NAG K 3 .   ? 134.393 134.534 97.566  1.00 32.90  ? 2   NAG d O4  1 
HETATM 13949 O O5  . NAG K 3 .   ? 137.651 134.849 99.196  1.00 32.90  ? 2   NAG d O5  1 
HETATM 13950 O O6  . NAG K 3 .   ? 137.575 135.604 96.483  1.00 32.90  ? 2   NAG d O6  1 
HETATM 13951 O O7  . NAG K 3 .   ? 135.991 137.865 102.497 1.00 32.90  ? 2   NAG d O7  1 
HETATM 13952 C C1  . BMA K 3 .   ? 133.733 135.551 96.785  1.00 40.37  ? 3   BMA d C1  1 
HETATM 13953 C C2  . BMA K 3 .   ? 133.933 135.254 95.302  1.00 40.37  ? 3   BMA d C2  1 
HETATM 13954 C C3  . BMA K 3 .   ? 133.183 136.270 94.451  1.00 40.37  ? 3   BMA d C3  1 
HETATM 13955 C C4  . BMA K 3 .   ? 131.721 136.342 94.868  1.00 40.37  ? 3   BMA d C4  1 
HETATM 13956 C C5  . BMA K 3 .   ? 131.619 136.599 96.369  1.00 40.37  ? 3   BMA d C5  1 
HETATM 13957 C C6  . BMA K 3 .   ? 130.198 136.565 96.881  1.00 40.37  ? 3   BMA d C6  1 
HETATM 13958 O O2  . BMA K 3 .   ? 133.472 133.938 95.011  1.00 40.37  ? 3   BMA d O2  1 
HETATM 13959 O O3  . BMA K 3 .   ? 133.280 135.919 93.074  1.00 40.37  ? 3   BMA d O3  1 
HETATM 13960 O O4  . BMA K 3 .   ? 131.064 137.395 94.169  1.00 40.37  ? 3   BMA d O4  1 
HETATM 13961 O O5  . BMA K 3 .   ? 132.336 135.581 97.084  1.00 40.37  ? 3   BMA d O5  1 
HETATM 13962 O O6  . BMA K 3 .   ? 130.164 136.690 98.295  1.00 40.37  ? 3   BMA d O6  1 
HETATM 13963 C C1  . MAN K 3 .   ? 133.871 137.020 92.355  1.00 88.95  ? 4   MAN d C1  1 
HETATM 13964 C C2  . MAN K 3 .   ? 133.192 137.131 90.995  1.00 88.95  ? 4   MAN d C2  1 
HETATM 13965 C C3  . MAN K 3 .   ? 133.470 135.881 90.171  1.00 88.95  ? 4   MAN d C3  1 
HETATM 13966 C C4  . MAN K 3 .   ? 134.969 135.622 90.087  1.00 88.95  ? 4   MAN d C4  1 
HETATM 13967 C C5  . MAN K 3 .   ? 135.576 135.592 91.488  1.00 88.95  ? 4   MAN d C5  1 
HETATM 13968 C C6  . MAN K 3 .   ? 137.082 135.459 91.478  1.00 88.95  ? 4   MAN d C6  1 
HETATM 13969 O O2  . MAN K 3 .   ? 133.668 138.286 90.313  1.00 88.95  ? 4   MAN d O2  1 
HETATM 13970 O O3  . MAN K 3 .   ? 132.924 136.023 88.864  1.00 88.95  ? 4   MAN d O3  1 
HETATM 13971 O O4  . MAN K 3 .   ? 135.216 134.377 89.443  1.00 88.95  ? 4   MAN d O4  1 
HETATM 13972 O O5  . MAN K 3 .   ? 135.273 136.822 92.167  1.00 88.95  ? 4   MAN d O5  1 
HETATM 13973 O O6  . MAN K 3 .   ? 137.493 134.256 90.843  1.00 88.95  ? 4   MAN d O6  1 
HETATM 13974 C C1  . MAN K 3 .   ? 128.848 137.110 98.699  1.00 106.10 ? 5   MAN d C1  1 
HETATM 13975 C C2  . MAN K 3 .   ? 128.996 138.178 99.775  1.00 102.11 ? 5   MAN d C2  1 
HETATM 13976 C C3  . MAN K 3 .   ? 129.671 137.584 101.004 1.00 108.28 ? 5   MAN d C3  1 
HETATM 13977 C C4  . MAN K 3 .   ? 128.911 136.352 101.477 1.00 111.51 ? 5   MAN d C4  1 
HETATM 13978 C C5  . MAN K 3 .   ? 128.751 135.364 100.325 1.00 107.21 ? 5   MAN d C5  1 
HETATM 13979 C C6  . MAN K 3 .   ? 127.903 134.166 100.685 1.00 104.28 ? 5   MAN d C6  1 
HETATM 13980 O O2  . MAN K 3 .   ? 127.713 138.691 100.118 1.00 94.59  ? 5   MAN d O2  1 
HETATM 13981 O O3  . MAN K 3 .   ? 129.731 138.554 102.045 1.00 92.09  ? 5   MAN d O3  1 
HETATM 13982 O O4  . MAN K 3 .   ? 129.617 135.720 102.541 1.00 115.13 ? 5   MAN d O4  1 
HETATM 13983 O O5  . MAN K 3 .   ? 128.098 136.013 99.222  1.00 110.78 ? 5   MAN d O5  1 
HETATM 13984 O O6  . MAN K 3 .   ? 127.721 133.307 99.567  1.00 99.51  ? 5   MAN d O6  1 
HETATM 13985 C C1  . NAG L 3 .   ? 132.139 162.807 121.611 1.00 35.92  ? 1   NAG e C1  1 
HETATM 13986 C C2  . NAG L 3 .   ? 131.250 164.038 121.440 1.00 37.93  ? 1   NAG e C2  1 
HETATM 13987 C C3  . NAG L 3 .   ? 131.628 164.803 120.173 1.00 39.84  ? 1   NAG e C3  1 
HETATM 13988 C C4  . NAG L 3 .   ? 133.129 165.056 120.087 1.00 40.79  ? 1   NAG e C4  1 
HETATM 13989 C C5  . NAG L 3 .   ? 133.899 163.760 120.318 1.00 42.00  ? 1   NAG e C5  1 
HETATM 13990 C C6  . NAG L 3 .   ? 135.396 163.963 120.374 1.00 46.33  ? 1   NAG e C6  1 
HETATM 13991 C C7  . NAG L 3 .   ? 128.912 164.220 122.171 1.00 36.59  ? 1   NAG e C7  1 
HETATM 13992 C C8  . NAG L 3 .   ? 127.507 163.737 121.959 1.00 30.16  ? 1   NAG e C8  1 
HETATM 13993 N N2  . NAG L 3 .   ? 129.849 163.653 121.403 1.00 35.11  ? 1   NAG e N2  1 
HETATM 13994 O O3  . NAG L 3 .   ? 130.931 166.045 120.158 1.00 42.37  ? 1   NAG e O3  1 
HETATM 13995 O O4  . NAG L 3 .   ? 133.456 165.535 118.787 1.00 45.55  ? 1   NAG e O4  1 
HETATM 13996 O O5  . NAG L 3 .   ? 133.509 163.197 121.578 1.00 40.46  ? 1   NAG e O5  1 
HETATM 13997 O O6  . NAG L 3 .   ? 136.089 162.723 120.362 1.00 48.01  ? 1   NAG e O6  1 
HETATM 13998 O O7  . NAG L 3 .   ? 129.186 165.081 123.003 1.00 45.09  ? 1   NAG e O7  1 
HETATM 13999 C C1  . NAG L 3 .   ? 133.851 166.917 118.815 1.00 50.77  ? 2   NAG e C1  1 
HETATM 14000 C C2  . NAG L 3 .   ? 134.835 167.135 117.667 1.00 48.88  ? 2   NAG e C2  1 
HETATM 14001 C C3  . NAG L 3 .   ? 135.232 168.607 117.573 1.00 49.87  ? 2   NAG e C3  1 
HETATM 14002 C C4  . NAG L 3 .   ? 133.997 169.496 117.517 1.00 51.86  ? 2   NAG e C4  1 
HETATM 14003 C C5  . NAG L 3 .   ? 133.074 169.179 118.689 1.00 50.64  ? 2   NAG e C5  1 
HETATM 14004 C C6  . NAG L 3 .   ? 131.771 169.946 118.646 1.00 47.79  ? 2   NAG e C6  1 
HETATM 14005 C C7  . NAG L 3 .   ? 136.292 165.277 117.001 1.00 46.30  ? 2   NAG e C7  1 
HETATM 14006 C C8  . NAG L 3 .   ? 137.555 164.521 117.297 1.00 41.41  ? 2   NAG e C8  1 
HETATM 14007 N N2  . NAG L 3 .   ? 136.011 166.294 117.823 1.00 48.07  ? 2   NAG e N2  1 
HETATM 14008 O O3  . NAG L 3 .   ? 136.034 168.808 116.414 1.00 51.69  ? 2   NAG e O3  1 
HETATM 14009 O O4  . NAG L 3 .   ? 134.375 170.869 117.554 1.00 64.93  ? 2   NAG e O4  1 
HETATM 14010 O O5  . NAG L 3 .   ? 132.731 167.786 118.658 1.00 54.14  ? 2   NAG e O5  1 
HETATM 14011 O O6  . NAG L 3 .   ? 130.948 169.635 119.762 1.00 47.20  ? 2   NAG e O6  1 
HETATM 14012 O O7  . NAG L 3 .   ? 135.558 164.975 116.065 1.00 45.39  ? 2   NAG e O7  1 
HETATM 14013 C C1  . BMA L 3 .   ? 133.995 171.495 116.307 1.00 70.59  ? 3   BMA e C1  1 
HETATM 14014 C C2  . BMA L 3 .   ? 134.145 173.007 116.468 1.00 74.28  ? 3   BMA e C2  1 
HETATM 14015 C C3  . BMA L 3 .   ? 133.827 173.726 115.163 1.00 78.96  ? 3   BMA e C3  1 
HETATM 14016 C C4  . BMA L 3 .   ? 134.619 173.131 114.006 1.00 77.48  ? 3   BMA e C4  1 
HETATM 14017 C C5  . BMA L 3 .   ? 134.431 171.618 113.958 1.00 68.43  ? 3   BMA e C5  1 
HETATM 14018 C C6  . BMA L 3 .   ? 135.287 170.958 112.901 1.00 59.79  ? 3   BMA e C6  1 
HETATM 14019 O O2  . BMA L 3 .   ? 135.472 173.312 116.887 1.00 71.14  ? 3   BMA e O2  1 
HETATM 14020 O O3  . BMA L 3 .   ? 134.138 175.110 115.284 1.00 75.10  ? 3   BMA e O3  1 
HETATM 14021 O O4  . BMA L 3 .   ? 134.179 173.693 112.773 1.00 74.99  ? 3   BMA e O4  1 
HETATM 14022 O O5  . BMA L 3 .   ? 134.807 171.044 115.220 1.00 73.42  ? 3   BMA e O5  1 
HETATM 14023 O O6  . BMA L 3 .   ? 136.667 171.221 113.125 1.00 69.74  ? 3   BMA e O6  1 
HETATM 14024 C C1  . MAN L 3 .   ? 133.089 175.790 115.996 1.00 3.56   ? 4   MAN e C1  1 
HETATM 14025 C C2  . MAN L 3 .   ? 132.067 176.305 114.991 1.00 3.66   ? 4   MAN e C2  1 
HETATM 14026 C C3  . MAN L 3 .   ? 132.729 177.310 114.061 1.00 4.16   ? 4   MAN e C3  1 
HETATM 14027 C C4  . MAN L 3 .   ? 133.372 178.424 114.875 1.00 7.11   ? 4   MAN e C4  1 
HETATM 14028 C C5  . MAN L 3 .   ? 134.324 177.830 115.910 1.00 4.98   ? 4   MAN e C5  1 
HETATM 14029 C C6  . MAN L 3 .   ? 134.916 178.869 116.836 1.00 4.09   ? 4   MAN e C6  1 
HETATM 14030 O O2  . MAN L 3 .   ? 130.980 176.915 115.680 1.00 1.83   ? 4   MAN e O2  1 
HETATM 14031 O O3  . MAN L 3 .   ? 131.769 177.853 113.160 1.00 10.36  ? 4   MAN e O3  1 
HETATM 14032 O O4  . MAN L 3 .   ? 134.097 179.301 114.018 1.00 14.40  ? 4   MAN e O4  1 
HETATM 14033 O O5  . MAN L 3 .   ? 133.615 176.893 116.736 1.00 4.01   ? 4   MAN e O5  1 
HETATM 14034 O O6  . MAN L 3 .   ? 135.890 178.298 117.699 1.00 3.54   ? 4   MAN e O6  1 
HETATM 14035 C C1  . MAN L 3 .   ? 137.450 170.712 112.021 1.00 70.20  ? 5   MAN e C1  1 
HETATM 14036 C C2  . MAN L 3 .   ? 138.919 170.729 112.441 1.00 75.14  ? 5   MAN e C2  1 
HETATM 14037 C C3  . MAN L 3 .   ? 139.407 172.162 112.620 1.00 77.29  ? 5   MAN e C3  1 
HETATM 14038 C C4  . MAN L 3 .   ? 139.112 172.983 111.372 1.00 79.24  ? 5   MAN e C4  1 
HETATM 14039 C C5  . MAN L 3 .   ? 137.631 172.876 111.020 1.00 80.93  ? 5   MAN e C5  1 
HETATM 14040 C C6  . MAN L 3 .   ? 137.280 173.589 109.734 1.00 80.03  ? 5   MAN e C6  1 
HETATM 14041 O O2  . MAN L 3 .   ? 139.706 170.062 111.460 1.00 67.57  ? 5   MAN e O2  1 
HETATM 14042 O O3  . MAN L 3 .   ? 140.804 172.174 112.895 1.00 70.49  ? 5   MAN e O3  1 
HETATM 14043 O O4  . MAN L 3 .   ? 139.443 174.351 111.593 1.00 77.40  ? 5   MAN e O4  1 
HETATM 14044 O O5  . MAN L 3 .   ? 137.289 171.494 110.833 1.00 73.42  ? 5   MAN e O5  1 
HETATM 14045 O O6  . MAN L 3 .   ? 135.891 173.497 109.449 1.00 81.80  ? 5   MAN e O6  1 
HETATM 14046 C C1  . NAG M 4 .   ? 114.800 160.800 90.986  1.00 70.35  ? 1   NAG H C1  1 
HETATM 14047 C C2  . NAG M 4 .   ? 113.304 161.109 90.992  1.00 69.98  ? 1   NAG H C2  1 
HETATM 14048 C C3  . NAG M 4 .   ? 113.078 162.613 91.125  1.00 75.41  ? 1   NAG H C3  1 
HETATM 14049 C C4  . NAG M 4 .   ? 113.805 163.139 92.355  1.00 76.83  ? 1   NAG H C4  1 
HETATM 14050 C C5  . NAG M 4 .   ? 115.281 162.760 92.281  1.00 73.66  ? 1   NAG H C5  1 
HETATM 14051 C C6  . NAG M 4 .   ? 116.058 163.164 93.513  1.00 68.86  ? 1   NAG H C6  1 
HETATM 14052 C C7  . NAG M 4 .   ? 111.349 160.479 89.633  1.00 73.75  ? 1   NAG H C7  1 
HETATM 14053 C C8  . NAG M 4 .   ? 110.885 159.906 88.325  1.00 78.83  ? 1   NAG H C8  1 
HETATM 14054 N N2  . NAG M 4 .   ? 112.674 160.593 89.787  1.00 69.23  ? 1   NAG H N2  1 
HETATM 14055 O O3  . NAG M 4 .   ? 111.684 162.887 91.232  1.00 78.42  ? 1   NAG H O3  1 
HETATM 14056 O O4  . NAG M 4 .   ? 113.692 164.557 92.425  1.00 72.62  ? 1   NAG H O4  1 
HETATM 14057 O O5  . NAG M 4 .   ? 115.407 161.334 92.163  1.00 73.01  ? 1   NAG H O5  1 
HETATM 14058 O O6  . NAG M 4 .   ? 117.422 162.779 93.415  1.00 56.48  ? 1   NAG H O6  1 
HETATM 14059 O O7  . NAG M 4 .   ? 110.559 160.808 90.514  1.00 71.32  ? 1   NAG H O7  1 
HETATM 14060 C C1  . NAG M 4 .   ? 112.743 164.902 93.452  1.00 27.90  ? 2   NAG H C1  1 
HETATM 14061 C C2  . NAG M 4 .   ? 113.088 166.288 93.993  1.00 27.90  ? 2   NAG H C2  1 
HETATM 14062 C C3  . NAG M 4 .   ? 112.073 166.706 95.051  1.00 27.90  ? 2   NAG H C3  1 
HETATM 14063 C C4  . NAG M 4 .   ? 110.666 166.623 94.476  1.00 27.90  ? 2   NAG H C4  1 
HETATM 14064 C C5  . NAG M 4 .   ? 110.412 165.226 93.916  1.00 27.90  ? 2   NAG H C5  1 
HETATM 14065 C C6  . NAG M 4 .   ? 109.072 165.099 93.228  1.00 27.90  ? 2   NAG H C6  1 
HETATM 14066 C C7  . NAG M 4 .   ? 115.485 166.799 93.866  1.00 27.90  ? 2   NAG H C7  1 
HETATM 14067 C C8  . NAG M 4 .   ? 116.803 166.755 94.581  1.00 27.90  ? 2   NAG H C8  1 
HETATM 14068 N N2  . NAG M 4 .   ? 114.437 166.310 94.537  1.00 27.90  ? 2   NAG H N2  1 
HETATM 14069 O O3  . NAG M 4 .   ? 112.350 168.038 95.474  1.00 27.90  ? 2   NAG H O3  1 
HETATM 14070 O O4  . NAG M 4 .   ? 109.705 166.904 95.490  1.00 27.90  ? 2   NAG H O4  1 
HETATM 14071 O O5  . NAG M 4 .   ? 111.411 164.908 92.933  1.00 27.90  ? 2   NAG H O5  1 
HETATM 14072 O O6  . NAG M 4 .   ? 108.008 165.470 94.094  1.00 27.90  ? 2   NAG H O6  1 
HETATM 14073 O O7  . NAG M 4 .   ? 115.374 167.261 92.733  1.00 27.90  ? 2   NAG H O7  1 
HETATM 14074 C C1  . PIO N 5 .   ? 105.710 146.947 176.656 1.00 79.00  ? 501 PIO A C1  1 
HETATM 14075 O O1  . PIO N 5 .   ? 106.253 147.171 175.339 1.00 71.61  ? 501 PIO A O1  1 
HETATM 14076 P P1  . PIO N 5 .   ? 105.578 146.450 174.050 1.00 68.99  ? 501 PIO A P1  1 
HETATM 14077 C C2  . PIO N 5 .   ? 105.573 148.288 177.363 1.00 80.72  ? 501 PIO A C2  1 
HETATM 14078 O O2  . PIO N 5 .   ? 106.838 148.938 177.429 1.00 75.53  ? 501 PIO A O2  1 
HETATM 14079 C C3  . PIO N 5 .   ? 105.015 148.086 178.765 1.00 86.11  ? 501 PIO A C3  1 
HETATM 14080 O O3  . PIO N 5 .   ? 104.917 149.338 179.436 1.00 83.23  ? 501 PIO A O3  1 
HETATM 14081 C C4  . PIO N 5 .   ? 105.910 147.138 179.550 1.00 92.45  ? 501 PIO A C4  1 
HETATM 14082 O O4  . PIO N 5 .   ? 105.303 146.881 180.834 1.00 98.40  ? 501 PIO A O4  1 
HETATM 14083 P P4  . PIO N 5 .   ? 105.590 147.808 182.139 1.00 98.61  ? 501 PIO A P4  1 
HETATM 14084 C C5  . PIO N 5 .   ? 106.084 145.817 178.820 1.00 91.75  ? 501 PIO A C5  1 
HETATM 14085 O O5  . PIO N 5 .   ? 106.996 144.988 179.570 1.00 95.91  ? 501 PIO A O5  1 
HETATM 14086 P P5  . PIO N 5 .   ? 106.551 143.555 180.198 1.00 96.78  ? 501 PIO A P5  1 
HETATM 14087 C C6  . PIO N 5 .   ? 106.643 146.018 177.419 1.00 80.91  ? 501 PIO A C6  1 
HETATM 14088 O O6  . PIO N 5 .   ? 106.739 144.767 176.745 1.00 75.17  ? 501 PIO A O6  1 
HETATM 14089 O O11 . PIO N 5 .   ? 106.605 145.872 173.152 1.00 67.29  ? 501 PIO A O11 1 
HETATM 14090 O O12 . PIO N 5 .   ? 104.426 145.612 174.443 1.00 65.99  ? 501 PIO A O12 1 
HETATM 14091 O O13 . PIO N 5 .   ? 104.990 147.767 173.367 1.00 69.18  ? 501 PIO A O13 1 
HETATM 14092 C C1A . PIO N 5 .   ? 103.173 149.741 171.120 1.00 71.45  ? 501 PIO A C1A 1 
HETATM 14093 O O1A . PIO N 5 .   ? 102.419 150.114 171.978 1.00 73.08  ? 501 PIO A O1A 1 
HETATM 14094 C C1B . PIO N 5 .   ? 106.480 151.954 170.153 1.00 65.58  ? 501 PIO A C1B 1 
HETATM 14095 O O1B . PIO N 5 .   ? 105.735 152.893 170.234 1.00 71.35  ? 501 PIO A O1B 1 
HETATM 14096 C C1C . PIO N 5 .   ? 105.861 148.889 173.111 1.00 65.20  ? 501 PIO A C1C 1 
HETATM 14097 C C2A . PIO N 5 .   ? 102.762 149.328 169.737 1.00 63.33  ? 501 PIO A C2A 1 
HETATM 14098 C C2B . PIO N 5 .   ? 107.326 151.630 168.955 1.00 59.20  ? 501 PIO A C2B 1 
HETATM 14099 C C2C . PIO N 5 .   ? 105.050 150.040 172.577 1.00 65.35  ? 501 PIO A C2C 1 
HETATM 14100 O O2C . PIO N 5 .   ? 104.500 149.644 171.283 1.00 70.71  ? 501 PIO A O2C 1 
HETATM 14101 C C3A . PIO N 5 .   ? 102.900 150.456 168.724 1.00 60.79  ? 501 PIO A C3A 1 
HETATM 14102 C C3B . PIO N 5 .   ? 106.591 150.799 167.911 1.00 61.11  ? 501 PIO A C3B 1 
HETATM 14103 C C3C . PIO N 5 .   ? 105.900 151.261 172.345 1.00 61.53  ? 501 PIO A C3C 1 
HETATM 14104 O O3C . PIO N 5 .   ? 106.658 151.062 171.130 1.00 62.32  ? 501 PIO A O3C 1 
HETATM 14105 O O41 . PIO N 5 .   ? 106.275 149.054 181.617 1.00 90.29  ? 501 PIO A O41 1 
HETATM 14106 O O42 . PIO N 5 .   ? 104.233 148.090 182.743 1.00 90.08  ? 501 PIO A O42 1 
HETATM 14107 O O43 . PIO N 5 .   ? 106.482 146.987 183.047 1.00 98.26  ? 501 PIO A O43 1 
HETATM 14108 C C4A . PIO N 5 .   ? 102.399 150.083 167.340 1.00 60.90  ? 501 PIO A C4A 1 
HETATM 14109 C C4B . PIO N 5 .   ? 107.457 150.446 166.713 1.00 58.20  ? 501 PIO A C4B 1 
HETATM 14110 O O51 . PIO N 5 .   ? 106.267 142.659 179.010 1.00 88.33  ? 501 PIO A O51 1 
HETATM 14111 O O52 . PIO N 5 .   ? 105.315 143.832 181.029 1.00 85.56  ? 501 PIO A O52 1 
HETATM 14112 O O53 . PIO N 5 .   ? 107.725 143.085 181.025 1.00 90.80  ? 501 PIO A O53 1 
HETATM 14113 C C5A . PIO N 5 .   ? 103.163 148.945 166.687 1.00 57.42  ? 501 PIO A C5A 1 
HETATM 14114 C C5B . PIO N 5 .   ? 106.770 149.541 165.702 1.00 53.22  ? 501 PIO A C5B 1 
HETATM 14115 C C6A . PIO N 5 .   ? 102.731 148.665 165.257 1.00 59.72  ? 501 PIO A C6A 1 
HETATM 14116 C C6B . PIO N 5 .   ? 107.656 149.130 164.536 1.00 58.29  ? 501 PIO A C6B 1 
HETATM 14117 C C7A . PIO N 5 .   ? 103.505 147.551 164.577 1.00 60.23  ? 501 PIO A C7A 1 
HETATM 14118 C C7B . PIO N 5 .   ? 106.985 148.183 163.554 1.00 56.63  ? 501 PIO A C7B 1 
HETATM 14119 C C8A . PIO N 5 .   ? 103.091 147.342 163.140 1.00 61.08  ? 501 PIO A C8A 1 
HETATM 14120 C C8B . PIO N 5 .   ? 107.880 147.787 162.399 1.00 40.82  ? 501 PIO A C8B 1 
HETATM 14121 C C1  . PIO O 5 .   ? 125.369 107.915 178.505 1.00 69.45  ? 501 PIO D C1  1 
HETATM 14122 O O1  . PIO O 5 .   ? 125.178 108.261 177.118 1.00 61.98  ? 501 PIO D O1  1 
HETATM 14123 P P1  . PIO O 5 .   ? 126.406 108.080 176.070 1.00 59.91  ? 501 PIO D P1  1 
HETATM 14124 C C2  . PIO O 5 .   ? 124.475 106.734 178.849 1.00 69.66  ? 501 PIO D C2  1 
HETATM 14125 O O2  . PIO O 5 .   ? 123.112 107.066 178.607 1.00 60.12  ? 501 PIO D O2  1 
HETATM 14126 C C3  . PIO O 5 .   ? 124.667 106.347 180.309 1.00 74.85  ? 501 PIO D C3  1 
HETATM 14127 O O3  . PIO O 5 .   ? 123.811 105.259 180.646 1.00 82.74  ? 501 PIO D O3  1 
HETATM 14128 C C4  . PIO O 5 .   ? 124.374 107.541 181.204 1.00 76.89  ? 501 PIO D C4  1 
HETATM 14129 O O4  . PIO O 5 .   ? 124.655 107.177 182.572 1.00 82.09  ? 501 PIO D O4  1 
HETATM 14130 P P4  . PIO O 5 .   ? 123.497 106.646 183.583 1.00 98.80  ? 501 PIO D P4  1 
HETATM 14131 C C5  . PIO O 5 .   ? 125.234 108.735 180.827 1.00 80.41  ? 501 PIO D C5  1 
HETATM 14132 O O5  . PIO O 5 .   ? 124.868 109.854 181.662 1.00 84.76  ? 501 PIO D O5  1 
HETATM 14133 P P5  . PIO O 5 .   ? 125.917 111.028 182.066 1.00 90.06  ? 501 PIO D P5  1 
HETATM 14134 C C6  . PIO O 5 .   ? 125.036 109.124 179.368 1.00 73.36  ? 501 PIO D C6  1 
HETATM 14135 O O6  . PIO O 5 .   ? 125.882 110.217 179.025 1.00 66.42  ? 501 PIO D O6  1 
HETATM 14136 O O11 . PIO O 5 .   ? 126.442 109.183 175.082 1.00 51.16  ? 501 PIO D O11 1 
HETATM 14137 O O12 . PIO O 5 .   ? 127.658 107.712 176.763 1.00 60.74  ? 501 PIO D O12 1 
HETATM 14138 O O13 . PIO O 5 .   ? 125.872 106.760 175.349 1.00 57.36  ? 501 PIO D O13 1 
HETATM 14139 C C1A . PIO O 5 .   ? 127.697 103.606 172.880 1.00 53.99  ? 501 PIO D C1A 1 
HETATM 14140 O O1A . PIO O 5 .   ? 127.867 103.167 173.986 1.00 57.24  ? 501 PIO D O1A 1 
HETATM 14141 C C1B . PIO O 5 .   ? 123.911 104.545 171.050 1.00 53.01  ? 501 PIO D C1B 1 
HETATM 14142 O O1B . PIO O 5 .   ? 123.085 103.946 171.684 1.00 54.55  ? 501 PIO D O1B 1 
HETATM 14143 C C1C . PIO O 5 .   ? 126.718 106.086 174.393 1.00 57.04  ? 501 PIO D C1C 1 
HETATM 14144 C C2A . PIO O 5 .   ? 128.476 103.197 171.663 1.00 47.03  ? 501 PIO D C2A 1 
HETATM 14145 C C2B . PIO O 5 .   ? 124.101 104.428 169.565 1.00 44.19  ? 501 PIO D C2B 1 
HETATM 14146 C C2C . PIO O 5 .   ? 125.931 105.034 173.657 1.00 55.25  ? 501 PIO D C2C 1 
HETATM 14147 O O2C . PIO O 5 .   ? 126.775 104.531 172.576 1.00 57.99  ? 501 PIO D O2C 1 
HETATM 14148 C C3A . PIO O 5 .   ? 128.397 104.217 170.535 1.00 47.92  ? 501 PIO D C3A 1 
HETATM 14149 C C3B . PIO O 5 .   ? 124.982 105.520 168.973 1.00 38.56  ? 501 PIO D C3B 1 
HETATM 14150 C C3C . PIO O 5 .   ? 124.694 105.606 173.019 1.00 53.31  ? 501 PIO D C3C 1 
HETATM 14151 O O3C . PIO O 5 .   ? 124.779 105.403 171.589 1.00 56.58  ? 501 PIO D O3C 1 
HETATM 14152 O O41 . PIO O 5 .   ? 122.422 106.044 182.702 1.00 90.74  ? 501 PIO D O41 1 
HETATM 14153 O O42 . PIO O 5 .   ? 123.024 107.865 184.342 1.00 97.00  ? 501 PIO D O42 1 
HETATM 14154 O O43 . PIO O 5 .   ? 124.167 105.619 184.472 1.00 96.67  ? 501 PIO D O43 1 
HETATM 14155 C C4A . PIO O 5 .   ? 129.176 103.802 169.298 1.00 39.98  ? 501 PIO D C4A 1 
HETATM 14156 C C4B . PIO O 5 .   ? 125.084 105.438 167.458 1.00 37.45  ? 501 PIO D C4B 1 
HETATM 14157 O O51 . PIO O 5 .   ? 125.370 111.653 183.333 1.00 84.58  ? 501 PIO D O51 1 
HETATM 14158 O O52 . PIO O 5 .   ? 125.921 111.988 180.894 1.00 75.53  ? 501 PIO D O52 1 
HETATM 14159 O O53 . PIO O 5 .   ? 127.249 110.344 182.272 1.00 80.51  ? 501 PIO D O53 1 
HETATM 14160 C C5A . PIO O 5 .   ? 129.185 104.849 168.196 1.00 34.66  ? 501 PIO D C5A 1 
HETATM 14161 C C5B . PIO O 5 .   ? 125.939 106.529 166.832 1.00 40.36  ? 501 PIO D C5B 1 
HETATM 14162 C C6A . PIO O 5 .   ? 129.993 104.451 166.971 1.00 37.74  ? 501 PIO D C6A 1 
HETATM 14163 C C6B . PIO O 5 .   ? 125.982 106.482 165.311 1.00 39.01  ? 501 PIO D C6B 1 
HETATM 14164 C C7A . PIO O 5 .   ? 130.133 105.552 165.932 1.00 36.40  ? 501 PIO D C7A 1 
HETATM 14165 C C7B . PIO O 5 .   ? 126.832 107.571 164.676 1.00 30.46  ? 501 PIO D C7B 1 
HETATM 14166 C C8A . PIO O 5 .   ? 130.987 105.149 164.752 1.00 32.83  ? 501 PIO D C8A 1 
HETATM 14167 C C8B . PIO O 5 .   ? 126.813 107.534 163.161 1.00 18.48  ? 501 PIO D C8B 1 
# 
