data_9FFQ
# 
_entry.id   9FFQ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FFQ         pdb_00009ffq 10.2210/pdb9ffq/pdb 
WWPDB D_1292138647 ?            ?                   
EMDB  EMD-50370    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-06-04 ? 
2 'EM metadata'     1 0 2025-06-04 ? 
3 'Additional map'  1 0 2025-06-04 1 
4 FSC               1 0 2025-06-04 ? 
5 'Half map'        1 0 2025-06-04 1 
6 'Half map'        1 0 2025-06-04 2 
7 Image             1 0 2025-06-04 ? 
8 Mask              1 0 2025-06-04 1 
9 'Primary map'     1 0 2025-06-04 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 FSC               repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 'Half map'        repository 'Initial release' ? ? 
7 7 Image             repository 'Initial release' ? ? 
8 8 Mask              repository 'Initial release' ? ? 
9 9 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FFQ 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
;Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric desensitised state of branch 1
;
_pdbx_database_related.db_id          EMD-50370 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              radu@mrc-lmb.cam.ac.uk 
_pdbx_contact_author.name_first         'A. Radu' 
_pdbx_contact_author.name_last          Aricescu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3783-1388 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Mihaylov, D.B.'  1 0000-0002-8375-3360 
'Malinauskas, T.' 2 0000-0002-4847-5529 
'Aricescu, A.R.'  3 0000-0003-3783-1388 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric desensitised state of branch 1
;
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Mihaylov, D.B.'  1 0000-0002-8375-3360 
primary 'Malinauskas, T.' 2 0000-0002-4847-5529 
primary 'Aricescu, A.R.'  3 0000-0003-3783-1388 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Gamma-aminobutyric acid receptor subunit alpha-1' 47059.648 2 ? ? ? ? 
2 polymer     man 'Gamma-aminobutyric acid receptor subunit beta-3' 45643.246 3 ? ? ? ? 
3 polymer     man 'Megabody25,Outer membrane protein' 56300.629 1 ? ? ? ? 
4 branched    man 
;alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
;
910.823   5 ? ? ? ? 
5 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   3 ? ? ? ? 
6 non-polymer syn 'CHLORIDE ION' 35.453    2 ? ? ? ? 
7 non-polymer syn 'GAMMA-AMINO-BUTANOIC ACID' 103.120   2 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'GABA(A) receptor subunit alpha-1' 
2 'GABA(A) receptor subunit beta-3'  
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MDEKTTGWRGGHVVEGLAGELEQLRARLEHHPQGQREPDYDIPTTENLYFQGTGQPSQDELKDNTTVFTRILDRLLDGYD
NRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKS
VAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSR
LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMT
TLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKSQPARAAKIDRLSRIAFPLLFGIFNLVYWATYLNR
EPQLKAPTPHQ
;
;MDEKTTGWRGGHVVEGLAGELEQLRARLEHHPQGQREPDYDIPTTENLYFQGTGQPSQDELKDNTTVFTRILDRLLDGYD
NRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKS
VAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSR
LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMT
TLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKSQPARAAKIDRLSRIAFPLLFGIFNLVYWATYLNR
EPQLKAPTPHQ
;
D,A   ? 
2 'polypeptide(L)' no no 
;MDEKTTGWRGGHVVEGLAGELEQLRARLEHHPQGQREPDYDIPTTENLYFQGTGQSVNDPGNMSFVKETVDKLLKGYDIR
LRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV
HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQF
SIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINT
HLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFSQPARAAAIDRWSRIVFPFTFSLFNLVYWLYYVN
;
;MDEKTTGWRGGHVVEGLAGELEQLRARLEHHPQGQREPDYDIPTTENLYFQGTGQSVNDPGNMSFVKETVDKLLKGYDIR
LRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV
HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQF
SIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINT
HLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFSQPARAAAIDRWSRIVFPFTFSLFNLVYWLYYVN
;
E,B,C ? 
3 'polypeptide(L)' no no 
;QVQLVESGGGLVQTKTTTSVIDTTNDAQNLLTQAQTIVNTLKDYCPILIAKSSSSNGGTNNANTPSWQTAGGGKNSCATF
GAEFSAASDMINNAQKIVQETQQLSANQPKNITQPHNLNLNSPSSLTALAQKMLKNAQSQAEILKLANQVESDFNKLSSG
HLKDYIGKCDASAISSANMTMQNQKNNWGNGCAGVEETQSLLKTSAADFNNQTPQINQAQNLANTLIQELGNNTYEQLSR
LLTNDNGTNSKTSAQAINQAVNNLNERAKTLAGGTTNSPAYQATLLALRSVLGLWNSMGYAVICGGYTKSPGENNQKDFH
YTDENGNGTTINCGGSTNSNGTHSYNGTNTLKADKNVSLSIEQYEKIHEAYQILSKALKQAGLAPLNSKGEKLEAHVTTS
KYGSLRLSCAASGHTFNYPIMGWFRQAPGKEREFVGAISWSGGSTSYADSVKDRFTISRDNAKNTVYLEMNNLKPEDTAV
YYCAAKGRYSGGLYYPTNYDYWGQGTQVTVSSHHHHHHEPEA
;
;QVQLVESGGGLVQTKTTTSVIDTTNDAQNLLTQAQTIVNTLKDYCPILIAKSSSSNGGTNNANTPSWQTAGGGKNSCATF
GAEFSAASDMINNAQKIVQETQQLSANQPKNITQPHNLNLNSPSSLTALAQKMLKNAQSQAEILKLANQVESDFNKLSSG
HLKDYIGKCDASAISSANMTMQNQKNNWGNGCAGVEETQSLLKTSAADFNNQTPQINQAQNLANTLIQELGNNTYEQLSR
LLTNDNGTNSKTSAQAINQAVNNLNERAKTLAGGTTNSPAYQATLLALRSVLGLWNSMGYAVICGGYTKSPGENNQKDFH
YTDENGNGTTINCGGSTNSNGTHSYNGTNTLKADKNVSLSIEQYEKIHEAYQILSKALKQAGLAPLNSKGEKLEAHVTTS
KYGSLRLSCAASGHTFNYPIMGWFRQAPGKEREFVGAISWSGGSTSYADSVKDRFTISRDNAKNTVYLEMNNLKPEDTAV
YYCAAKGRYSGGLYYPTNYDYWGQGTQVTVSSHHHHHHEPEA
;
F     ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
6 'CHLORIDE ION'              CL  
7 'GAMMA-AMINO-BUTANOIC ACID' ABU 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   GLU n 
1 4   LYS n 
1 5   THR n 
1 6   THR n 
1 7   GLY n 
1 8   TRP n 
1 9   ARG n 
1 10  GLY n 
1 11  GLY n 
1 12  HIS n 
1 13  VAL n 
1 14  VAL n 
1 15  GLU n 
1 16  GLY n 
1 17  LEU n 
1 18  ALA n 
1 19  GLY n 
1 20  GLU n 
1 21  LEU n 
1 22  GLU n 
1 23  GLN n 
1 24  LEU n 
1 25  ARG n 
1 26  ALA n 
1 27  ARG n 
1 28  LEU n 
1 29  GLU n 
1 30  HIS n 
1 31  HIS n 
1 32  PRO n 
1 33  GLN n 
1 34  GLY n 
1 35  GLN n 
1 36  ARG n 
1 37  GLU n 
1 38  PRO n 
1 39  ASP n 
1 40  TYR n 
1 41  ASP n 
1 42  ILE n 
1 43  PRO n 
1 44  THR n 
1 45  THR n 
1 46  GLU n 
1 47  ASN n 
1 48  LEU n 
1 49  TYR n 
1 50  PHE n 
1 51  GLN n 
1 52  GLY n 
1 53  THR n 
1 54  GLY n 
1 55  GLN n 
1 56  PRO n 
1 57  SER n 
1 58  GLN n 
1 59  ASP n 
1 60  GLU n 
1 61  LEU n 
1 62  LYS n 
1 63  ASP n 
1 64  ASN n 
1 65  THR n 
1 66  THR n 
1 67  VAL n 
1 68  PHE n 
1 69  THR n 
1 70  ARG n 
1 71  ILE n 
1 72  LEU n 
1 73  ASP n 
1 74  ARG n 
1 75  LEU n 
1 76  LEU n 
1 77  ASP n 
1 78  GLY n 
1 79  TYR n 
1 80  ASP n 
1 81  ASN n 
1 82  ARG n 
1 83  LEU n 
1 84  ARG n 
1 85  PRO n 
1 86  GLY n 
1 87  LEU n 
1 88  GLY n 
1 89  GLU n 
1 90  ARG n 
1 91  VAL n 
1 92  THR n 
1 93  GLU n 
1 94  VAL n 
1 95  LYS n 
1 96  THR n 
1 97  ASP n 
1 98  ILE n 
1 99  PHE n 
1 100 VAL n 
1 101 THR n 
1 102 SER n 
1 103 PHE n 
1 104 GLY n 
1 105 PRO n 
1 106 VAL n 
1 107 SER n 
1 108 ASP n 
1 109 HIS n 
1 110 ASP n 
1 111 MET n 
1 112 GLU n 
1 113 TYR n 
1 114 THR n 
1 115 ILE n 
1 116 ASP n 
1 117 VAL n 
1 118 PHE n 
1 119 PHE n 
1 120 ARG n 
1 121 GLN n 
1 122 SER n 
1 123 TRP n 
1 124 LYS n 
1 125 ASP n 
1 126 GLU n 
1 127 ARG n 
1 128 LEU n 
1 129 LYS n 
1 130 PHE n 
1 131 LYS n 
1 132 GLY n 
1 133 PRO n 
1 134 MET n 
1 135 THR n 
1 136 VAL n 
1 137 LEU n 
1 138 ARG n 
1 139 LEU n 
1 140 ASN n 
1 141 ASN n 
1 142 LEU n 
1 143 MET n 
1 144 ALA n 
1 145 SER n 
1 146 LYS n 
1 147 ILE n 
1 148 TRP n 
1 149 THR n 
1 150 PRO n 
1 151 ASP n 
1 152 THR n 
1 153 PHE n 
1 154 PHE n 
1 155 HIS n 
1 156 ASN n 
1 157 GLY n 
1 158 LYS n 
1 159 LYS n 
1 160 SER n 
1 161 VAL n 
1 162 ALA n 
1 163 HIS n 
1 164 ASN n 
1 165 MET n 
1 166 THR n 
1 167 MET n 
1 168 PRO n 
1 169 ASN n 
1 170 LYS n 
1 171 LEU n 
1 172 LEU n 
1 173 ARG n 
1 174 ILE n 
1 175 THR n 
1 176 GLU n 
1 177 ASP n 
1 178 GLY n 
1 179 THR n 
1 180 LEU n 
1 181 LEU n 
1 182 TYR n 
1 183 THR n 
1 184 MET n 
1 185 ARG n 
1 186 LEU n 
1 187 THR n 
1 188 VAL n 
1 189 ARG n 
1 190 ALA n 
1 191 GLU n 
1 192 CYS n 
1 193 PRO n 
1 194 MET n 
1 195 HIS n 
1 196 LEU n 
1 197 GLU n 
1 198 ASP n 
1 199 PHE n 
1 200 PRO n 
1 201 MET n 
1 202 ASP n 
1 203 ALA n 
1 204 HIS n 
1 205 ALA n 
1 206 CYS n 
1 207 PRO n 
1 208 LEU n 
1 209 LYS n 
1 210 PHE n 
1 211 GLY n 
1 212 SER n 
1 213 TYR n 
1 214 ALA n 
1 215 TYR n 
1 216 THR n 
1 217 ARG n 
1 218 ALA n 
1 219 GLU n 
1 220 VAL n 
1 221 VAL n 
1 222 TYR n 
1 223 GLU n 
1 224 TRP n 
1 225 THR n 
1 226 ARG n 
1 227 GLU n 
1 228 PRO n 
1 229 ALA n 
1 230 ARG n 
1 231 SER n 
1 232 VAL n 
1 233 VAL n 
1 234 VAL n 
1 235 ALA n 
1 236 GLU n 
1 237 ASP n 
1 238 GLY n 
1 239 SER n 
1 240 ARG n 
1 241 LEU n 
1 242 ASN n 
1 243 GLN n 
1 244 TYR n 
1 245 ASP n 
1 246 LEU n 
1 247 LEU n 
1 248 GLY n 
1 249 GLN n 
1 250 THR n 
1 251 VAL n 
1 252 ASP n 
1 253 SER n 
1 254 GLY n 
1 255 ILE n 
1 256 VAL n 
1 257 GLN n 
1 258 SER n 
1 259 SER n 
1 260 THR n 
1 261 GLY n 
1 262 GLU n 
1 263 TYR n 
1 264 VAL n 
1 265 VAL n 
1 266 MET n 
1 267 THR n 
1 268 THR n 
1 269 HIS n 
1 270 PHE n 
1 271 HIS n 
1 272 LEU n 
1 273 LYS n 
1 274 ARG n 
1 275 LYS n 
1 276 ILE n 
1 277 GLY n 
1 278 TYR n 
1 279 PHE n 
1 280 VAL n 
1 281 ILE n 
1 282 GLN n 
1 283 THR n 
1 284 TYR n 
1 285 LEU n 
1 286 PRO n 
1 287 CYS n 
1 288 ILE n 
1 289 MET n 
1 290 THR n 
1 291 VAL n 
1 292 ILE n 
1 293 LEU n 
1 294 SER n 
1 295 GLN n 
1 296 VAL n 
1 297 SER n 
1 298 PHE n 
1 299 TRP n 
1 300 LEU n 
1 301 ASN n 
1 302 ARG n 
1 303 GLU n 
1 304 SER n 
1 305 VAL n 
1 306 PRO n 
1 307 ALA n 
1 308 ARG n 
1 309 THR n 
1 310 VAL n 
1 311 PHE n 
1 312 GLY n 
1 313 VAL n 
1 314 THR n 
1 315 THR n 
1 316 VAL n 
1 317 LEU n 
1 318 THR n 
1 319 MET n 
1 320 THR n 
1 321 THR n 
1 322 LEU n 
1 323 SER n 
1 324 ILE n 
1 325 SER n 
1 326 ALA n 
1 327 ARG n 
1 328 ASN n 
1 329 SER n 
1 330 LEU n 
1 331 PRO n 
1 332 LYS n 
1 333 VAL n 
1 334 ALA n 
1 335 TYR n 
1 336 ALA n 
1 337 THR n 
1 338 ALA n 
1 339 MET n 
1 340 ASP n 
1 341 TRP n 
1 342 PHE n 
1 343 ILE n 
1 344 ALA n 
1 345 VAL n 
1 346 CYS n 
1 347 TYR n 
1 348 ALA n 
1 349 PHE n 
1 350 VAL n 
1 351 PHE n 
1 352 SER n 
1 353 ALA n 
1 354 LEU n 
1 355 ILE n 
1 356 GLU n 
1 357 PHE n 
1 358 ALA n 
1 359 THR n 
1 360 VAL n 
1 361 ASN n 
1 362 TYR n 
1 363 PHE n 
1 364 THR n 
1 365 LYS n 
1 366 SER n 
1 367 GLN n 
1 368 PRO n 
1 369 ALA n 
1 370 ARG n 
1 371 ALA n 
1 372 ALA n 
1 373 LYS n 
1 374 ILE n 
1 375 ASP n 
1 376 ARG n 
1 377 LEU n 
1 378 SER n 
1 379 ARG n 
1 380 ILE n 
1 381 ALA n 
1 382 PHE n 
1 383 PRO n 
1 384 LEU n 
1 385 LEU n 
1 386 PHE n 
1 387 GLY n 
1 388 ILE n 
1 389 PHE n 
1 390 ASN n 
1 391 LEU n 
1 392 VAL n 
1 393 TYR n 
1 394 TRP n 
1 395 ALA n 
1 396 THR n 
1 397 TYR n 
1 398 LEU n 
1 399 ASN n 
1 400 ARG n 
1 401 GLU n 
1 402 PRO n 
1 403 GLN n 
1 404 LEU n 
1 405 LYS n 
1 406 ALA n 
1 407 PRO n 
1 408 THR n 
1 409 PRO n 
1 410 HIS n 
1 411 GLN n 
2 1   MET n 
2 2   ASP n 
2 3   GLU n 
2 4   LYS n 
2 5   THR n 
2 6   THR n 
2 7   GLY n 
2 8   TRP n 
2 9   ARG n 
2 10  GLY n 
2 11  GLY n 
2 12  HIS n 
2 13  VAL n 
2 14  VAL n 
2 15  GLU n 
2 16  GLY n 
2 17  LEU n 
2 18  ALA n 
2 19  GLY n 
2 20  GLU n 
2 21  LEU n 
2 22  GLU n 
2 23  GLN n 
2 24  LEU n 
2 25  ARG n 
2 26  ALA n 
2 27  ARG n 
2 28  LEU n 
2 29  GLU n 
2 30  HIS n 
2 31  HIS n 
2 32  PRO n 
2 33  GLN n 
2 34  GLY n 
2 35  GLN n 
2 36  ARG n 
2 37  GLU n 
2 38  PRO n 
2 39  ASP n 
2 40  TYR n 
2 41  ASP n 
2 42  ILE n 
2 43  PRO n 
2 44  THR n 
2 45  THR n 
2 46  GLU n 
2 47  ASN n 
2 48  LEU n 
2 49  TYR n 
2 50  PHE n 
2 51  GLN n 
2 52  GLY n 
2 53  THR n 
2 54  GLY n 
2 55  GLN n 
2 56  SER n 
2 57  VAL n 
2 58  ASN n 
2 59  ASP n 
2 60  PRO n 
2 61  GLY n 
2 62  ASN n 
2 63  MET n 
2 64  SER n 
2 65  PHE n 
2 66  VAL n 
2 67  LYS n 
2 68  GLU n 
2 69  THR n 
2 70  VAL n 
2 71  ASP n 
2 72  LYS n 
2 73  LEU n 
2 74  LEU n 
2 75  LYS n 
2 76  GLY n 
2 77  TYR n 
2 78  ASP n 
2 79  ILE n 
2 80  ARG n 
2 81  LEU n 
2 82  ARG n 
2 83  PRO n 
2 84  ASP n 
2 85  PHE n 
2 86  GLY n 
2 87  GLY n 
2 88  PRO n 
2 89  PRO n 
2 90  VAL n 
2 91  CYS n 
2 92  VAL n 
2 93  GLY n 
2 94  MET n 
2 95  ASN n 
2 96  ILE n 
2 97  ASP n 
2 98  ILE n 
2 99  ALA n 
2 100 SER n 
2 101 ILE n 
2 102 ASP n 
2 103 MET n 
2 104 VAL n 
2 105 SER n 
2 106 GLU n 
2 107 VAL n 
2 108 ASN n 
2 109 MET n 
2 110 ASP n 
2 111 TYR n 
2 112 THR n 
2 113 LEU n 
2 114 THR n 
2 115 MET n 
2 116 TYR n 
2 117 PHE n 
2 118 GLN n 
2 119 GLN n 
2 120 TYR n 
2 121 TRP n 
2 122 ARG n 
2 123 ASP n 
2 124 LYS n 
2 125 ARG n 
2 126 LEU n 
2 127 ALA n 
2 128 TYR n 
2 129 SER n 
2 130 GLY n 
2 131 ILE n 
2 132 PRO n 
2 133 LEU n 
2 134 ASN n 
2 135 LEU n 
2 136 THR n 
2 137 LEU n 
2 138 ASP n 
2 139 ASN n 
2 140 ARG n 
2 141 VAL n 
2 142 ALA n 
2 143 ASP n 
2 144 GLN n 
2 145 LEU n 
2 146 TRP n 
2 147 VAL n 
2 148 PRO n 
2 149 ASP n 
2 150 THR n 
2 151 TYR n 
2 152 PHE n 
2 153 LEU n 
2 154 ASN n 
2 155 ASP n 
2 156 LYS n 
2 157 LYS n 
2 158 SER n 
2 159 PHE n 
2 160 VAL n 
2 161 HIS n 
2 162 GLY n 
2 163 VAL n 
2 164 THR n 
2 165 VAL n 
2 166 LYS n 
2 167 ASN n 
2 168 ARG n 
2 169 MET n 
2 170 ILE n 
2 171 ARG n 
2 172 LEU n 
2 173 HIS n 
2 174 PRO n 
2 175 ASP n 
2 176 GLY n 
2 177 THR n 
2 178 VAL n 
2 179 LEU n 
2 180 TYR n 
2 181 GLY n 
2 182 LEU n 
2 183 ARG n 
2 184 ILE n 
2 185 THR n 
2 186 THR n 
2 187 THR n 
2 188 ALA n 
2 189 ALA n 
2 190 CYS n 
2 191 MET n 
2 192 MET n 
2 193 ASP n 
2 194 LEU n 
2 195 ARG n 
2 196 ARG n 
2 197 TYR n 
2 198 PRO n 
2 199 LEU n 
2 200 ASP n 
2 201 GLU n 
2 202 GLN n 
2 203 ASN n 
2 204 CYS n 
2 205 THR n 
2 206 LEU n 
2 207 GLU n 
2 208 ILE n 
2 209 GLU n 
2 210 SER n 
2 211 TYR n 
2 212 GLY n 
2 213 TYR n 
2 214 THR n 
2 215 THR n 
2 216 ASP n 
2 217 ASP n 
2 218 ILE n 
2 219 GLU n 
2 220 PHE n 
2 221 TYR n 
2 222 TRP n 
2 223 ARG n 
2 224 GLY n 
2 225 GLY n 
2 226 ASP n 
2 227 LYS n 
2 228 ALA n 
2 229 VAL n 
2 230 THR n 
2 231 GLY n 
2 232 VAL n 
2 233 GLU n 
2 234 ARG n 
2 235 ILE n 
2 236 GLU n 
2 237 LEU n 
2 238 PRO n 
2 239 GLN n 
2 240 PHE n 
2 241 SER n 
2 242 ILE n 
2 243 VAL n 
2 244 GLU n 
2 245 HIS n 
2 246 ARG n 
2 247 LEU n 
2 248 VAL n 
2 249 SER n 
2 250 ARG n 
2 251 ASN n 
2 252 VAL n 
2 253 VAL n 
2 254 PHE n 
2 255 ALA n 
2 256 THR n 
2 257 GLY n 
2 258 ALA n 
2 259 TYR n 
2 260 PRO n 
2 261 ARG n 
2 262 LEU n 
2 263 SER n 
2 264 LEU n 
2 265 SER n 
2 266 PHE n 
2 267 ARG n 
2 268 LEU n 
2 269 LYS n 
2 270 ARG n 
2 271 ASN n 
2 272 ILE n 
2 273 GLY n 
2 274 TYR n 
2 275 PHE n 
2 276 ILE n 
2 277 LEU n 
2 278 GLN n 
2 279 THR n 
2 280 TYR n 
2 281 MET n 
2 282 PRO n 
2 283 SER n 
2 284 ILE n 
2 285 LEU n 
2 286 ILE n 
2 287 THR n 
2 288 ILE n 
2 289 LEU n 
2 290 SER n 
2 291 TRP n 
2 292 VAL n 
2 293 SER n 
2 294 PHE n 
2 295 TRP n 
2 296 ILE n 
2 297 ASN n 
2 298 TYR n 
2 299 ASP n 
2 300 ALA n 
2 301 SER n 
2 302 ALA n 
2 303 ALA n 
2 304 ARG n 
2 305 VAL n 
2 306 ALA n 
2 307 LEU n 
2 308 GLY n 
2 309 ILE n 
2 310 THR n 
2 311 THR n 
2 312 VAL n 
2 313 LEU n 
2 314 THR n 
2 315 MET n 
2 316 THR n 
2 317 THR n 
2 318 ILE n 
2 319 ASN n 
2 320 THR n 
2 321 HIS n 
2 322 LEU n 
2 323 ARG n 
2 324 GLU n 
2 325 THR n 
2 326 LEU n 
2 327 PRO n 
2 328 LYS n 
2 329 ILE n 
2 330 PRO n 
2 331 TYR n 
2 332 VAL n 
2 333 LYS n 
2 334 ALA n 
2 335 ILE n 
2 336 ASP n 
2 337 MET n 
2 338 TYR n 
2 339 LEU n 
2 340 MET n 
2 341 GLY n 
2 342 CYS n 
2 343 PHE n 
2 344 VAL n 
2 345 PHE n 
2 346 VAL n 
2 347 PHE n 
2 348 LEU n 
2 349 ALA n 
2 350 LEU n 
2 351 LEU n 
2 352 GLU n 
2 353 TYR n 
2 354 ALA n 
2 355 PHE n 
2 356 VAL n 
2 357 ASN n 
2 358 TYR n 
2 359 ILE n 
2 360 PHE n 
2 361 PHE n 
2 362 SER n 
2 363 GLN n 
2 364 PRO n 
2 365 ALA n 
2 366 ARG n 
2 367 ALA n 
2 368 ALA n 
2 369 ALA n 
2 370 ILE n 
2 371 ASP n 
2 372 ARG n 
2 373 TRP n 
2 374 SER n 
2 375 ARG n 
2 376 ILE n 
2 377 VAL n 
2 378 PHE n 
2 379 PRO n 
2 380 PHE n 
2 381 THR n 
2 382 PHE n 
2 383 SER n 
2 384 LEU n 
2 385 PHE n 
2 386 ASN n 
2 387 LEU n 
2 388 VAL n 
2 389 TYR n 
2 390 TRP n 
2 391 LEU n 
2 392 TYR n 
2 393 TYR n 
2 394 VAL n 
2 395 ASN n 
3 1   GLN n 
3 2   VAL n 
3 3   GLN n 
3 4   LEU n 
3 5   VAL n 
3 6   GLU n 
3 7   SER n 
3 8   GLY n 
3 9   GLY n 
3 10  GLY n 
3 11  LEU n 
3 12  VAL n 
3 13  GLN n 
3 14  THR n 
3 15  LYS n 
3 16  THR n 
3 17  THR n 
3 18  THR n 
3 19  SER n 
3 20  VAL n 
3 21  ILE n 
3 22  ASP n 
3 23  THR n 
3 24  THR n 
3 25  ASN n 
3 26  ASP n 
3 27  ALA n 
3 28  GLN n 
3 29  ASN n 
3 30  LEU n 
3 31  LEU n 
3 32  THR n 
3 33  GLN n 
3 34  ALA n 
3 35  GLN n 
3 36  THR n 
3 37  ILE n 
3 38  VAL n 
3 39  ASN n 
3 40  THR n 
3 41  LEU n 
3 42  LYS n 
3 43  ASP n 
3 44  TYR n 
3 45  CYS n 
3 46  PRO n 
3 47  ILE n 
3 48  LEU n 
3 49  ILE n 
3 50  ALA n 
3 51  LYS n 
3 52  SER n 
3 53  SER n 
3 54  SER n 
3 55  SER n 
3 56  ASN n 
3 57  GLY n 
3 58  GLY n 
3 59  THR n 
3 60  ASN n 
3 61  ASN n 
3 62  ALA n 
3 63  ASN n 
3 64  THR n 
3 65  PRO n 
3 66  SER n 
3 67  TRP n 
3 68  GLN n 
3 69  THR n 
3 70  ALA n 
3 71  GLY n 
3 72  GLY n 
3 73  GLY n 
3 74  LYS n 
3 75  ASN n 
3 76  SER n 
3 77  CYS n 
3 78  ALA n 
3 79  THR n 
3 80  PHE n 
3 81  GLY n 
3 82  ALA n 
3 83  GLU n 
3 84  PHE n 
3 85  SER n 
3 86  ALA n 
3 87  ALA n 
3 88  SER n 
3 89  ASP n 
3 90  MET n 
3 91  ILE n 
3 92  ASN n 
3 93  ASN n 
3 94  ALA n 
3 95  GLN n 
3 96  LYS n 
3 97  ILE n 
3 98  VAL n 
3 99  GLN n 
3 100 GLU n 
3 101 THR n 
3 102 GLN n 
3 103 GLN n 
3 104 LEU n 
3 105 SER n 
3 106 ALA n 
3 107 ASN n 
3 108 GLN n 
3 109 PRO n 
3 110 LYS n 
3 111 ASN n 
3 112 ILE n 
3 113 THR n 
3 114 GLN n 
3 115 PRO n 
3 116 HIS n 
3 117 ASN n 
3 118 LEU n 
3 119 ASN n 
3 120 LEU n 
3 121 ASN n 
3 122 SER n 
3 123 PRO n 
3 124 SER n 
3 125 SER n 
3 126 LEU n 
3 127 THR n 
3 128 ALA n 
3 129 LEU n 
3 130 ALA n 
3 131 GLN n 
3 132 LYS n 
3 133 MET n 
3 134 LEU n 
3 135 LYS n 
3 136 ASN n 
3 137 ALA n 
3 138 GLN n 
3 139 SER n 
3 140 GLN n 
3 141 ALA n 
3 142 GLU n 
3 143 ILE n 
3 144 LEU n 
3 145 LYS n 
3 146 LEU n 
3 147 ALA n 
3 148 ASN n 
3 149 GLN n 
3 150 VAL n 
3 151 GLU n 
3 152 SER n 
3 153 ASP n 
3 154 PHE n 
3 155 ASN n 
3 156 LYS n 
3 157 LEU n 
3 158 SER n 
3 159 SER n 
3 160 GLY n 
3 161 HIS n 
3 162 LEU n 
3 163 LYS n 
3 164 ASP n 
3 165 TYR n 
3 166 ILE n 
3 167 GLY n 
3 168 LYS n 
3 169 CYS n 
3 170 ASP n 
3 171 ALA n 
3 172 SER n 
3 173 ALA n 
3 174 ILE n 
3 175 SER n 
3 176 SER n 
3 177 ALA n 
3 178 ASN n 
3 179 MET n 
3 180 THR n 
3 181 MET n 
3 182 GLN n 
3 183 ASN n 
3 184 GLN n 
3 185 LYS n 
3 186 ASN n 
3 187 ASN n 
3 188 TRP n 
3 189 GLY n 
3 190 ASN n 
3 191 GLY n 
3 192 CYS n 
3 193 ALA n 
3 194 GLY n 
3 195 VAL n 
3 196 GLU n 
3 197 GLU n 
3 198 THR n 
3 199 GLN n 
3 200 SER n 
3 201 LEU n 
3 202 LEU n 
3 203 LYS n 
3 204 THR n 
3 205 SER n 
3 206 ALA n 
3 207 ALA n 
3 208 ASP n 
3 209 PHE n 
3 210 ASN n 
3 211 ASN n 
3 212 GLN n 
3 213 THR n 
3 214 PRO n 
3 215 GLN n 
3 216 ILE n 
3 217 ASN n 
3 218 GLN n 
3 219 ALA n 
3 220 GLN n 
3 221 ASN n 
3 222 LEU n 
3 223 ALA n 
3 224 ASN n 
3 225 THR n 
3 226 LEU n 
3 227 ILE n 
3 228 GLN n 
3 229 GLU n 
3 230 LEU n 
3 231 GLY n 
3 232 ASN n 
3 233 ASN n 
3 234 THR n 
3 235 TYR n 
3 236 GLU n 
3 237 GLN n 
3 238 LEU n 
3 239 SER n 
3 240 ARG n 
3 241 LEU n 
3 242 LEU n 
3 243 THR n 
3 244 ASN n 
3 245 ASP n 
3 246 ASN n 
3 247 GLY n 
3 248 THR n 
3 249 ASN n 
3 250 SER n 
3 251 LYS n 
3 252 THR n 
3 253 SER n 
3 254 ALA n 
3 255 GLN n 
3 256 ALA n 
3 257 ILE n 
3 258 ASN n 
3 259 GLN n 
3 260 ALA n 
3 261 VAL n 
3 262 ASN n 
3 263 ASN n 
3 264 LEU n 
3 265 ASN n 
3 266 GLU n 
3 267 ARG n 
3 268 ALA n 
3 269 LYS n 
3 270 THR n 
3 271 LEU n 
3 272 ALA n 
3 273 GLY n 
3 274 GLY n 
3 275 THR n 
3 276 THR n 
3 277 ASN n 
3 278 SER n 
3 279 PRO n 
3 280 ALA n 
3 281 TYR n 
3 282 GLN n 
3 283 ALA n 
3 284 THR n 
3 285 LEU n 
3 286 LEU n 
3 287 ALA n 
3 288 LEU n 
3 289 ARG n 
3 290 SER n 
3 291 VAL n 
3 292 LEU n 
3 293 GLY n 
3 294 LEU n 
3 295 TRP n 
3 296 ASN n 
3 297 SER n 
3 298 MET n 
3 299 GLY n 
3 300 TYR n 
3 301 ALA n 
3 302 VAL n 
3 303 ILE n 
3 304 CYS n 
3 305 GLY n 
3 306 GLY n 
3 307 TYR n 
3 308 THR n 
3 309 LYS n 
3 310 SER n 
3 311 PRO n 
3 312 GLY n 
3 313 GLU n 
3 314 ASN n 
3 315 ASN n 
3 316 GLN n 
3 317 LYS n 
3 318 ASP n 
3 319 PHE n 
3 320 HIS n 
3 321 TYR n 
3 322 THR n 
3 323 ASP n 
3 324 GLU n 
3 325 ASN n 
3 326 GLY n 
3 327 ASN n 
3 328 GLY n 
3 329 THR n 
3 330 THR n 
3 331 ILE n 
3 332 ASN n 
3 333 CYS n 
3 334 GLY n 
3 335 GLY n 
3 336 SER n 
3 337 THR n 
3 338 ASN n 
3 339 SER n 
3 340 ASN n 
3 341 GLY n 
3 342 THR n 
3 343 HIS n 
3 344 SER n 
3 345 TYR n 
3 346 ASN n 
3 347 GLY n 
3 348 THR n 
3 349 ASN n 
3 350 THR n 
3 351 LEU n 
3 352 LYS n 
3 353 ALA n 
3 354 ASP n 
3 355 LYS n 
3 356 ASN n 
3 357 VAL n 
3 358 SER n 
3 359 LEU n 
3 360 SER n 
3 361 ILE n 
3 362 GLU n 
3 363 GLN n 
3 364 TYR n 
3 365 GLU n 
3 366 LYS n 
3 367 ILE n 
3 368 HIS n 
3 369 GLU n 
3 370 ALA n 
3 371 TYR n 
3 372 GLN n 
3 373 ILE n 
3 374 LEU n 
3 375 SER n 
3 376 LYS n 
3 377 ALA n 
3 378 LEU n 
3 379 LYS n 
3 380 GLN n 
3 381 ALA n 
3 382 GLY n 
3 383 LEU n 
3 384 ALA n 
3 385 PRO n 
3 386 LEU n 
3 387 ASN n 
3 388 SER n 
3 389 LYS n 
3 390 GLY n 
3 391 GLU n 
3 392 LYS n 
3 393 LEU n 
3 394 GLU n 
3 395 ALA n 
3 396 HIS n 
3 397 VAL n 
3 398 THR n 
3 399 THR n 
3 400 SER n 
3 401 LYS n 
3 402 TYR n 
3 403 GLY n 
3 404 SER n 
3 405 LEU n 
3 406 ARG n 
3 407 LEU n 
3 408 SER n 
3 409 CYS n 
3 410 ALA n 
3 411 ALA n 
3 412 SER n 
3 413 GLY n 
3 414 HIS n 
3 415 THR n 
3 416 PHE n 
3 417 ASN n 
3 418 TYR n 
3 419 PRO n 
3 420 ILE n 
3 421 MET n 
3 422 GLY n 
3 423 TRP n 
3 424 PHE n 
3 425 ARG n 
3 426 GLN n 
3 427 ALA n 
3 428 PRO n 
3 429 GLY n 
3 430 LYS n 
3 431 GLU n 
3 432 ARG n 
3 433 GLU n 
3 434 PHE n 
3 435 VAL n 
3 436 GLY n 
3 437 ALA n 
3 438 ILE n 
3 439 SER n 
3 440 TRP n 
3 441 SER n 
3 442 GLY n 
3 443 GLY n 
3 444 SER n 
3 445 THR n 
3 446 SER n 
3 447 TYR n 
3 448 ALA n 
3 449 ASP n 
3 450 SER n 
3 451 VAL n 
3 452 LYS n 
3 453 ASP n 
3 454 ARG n 
3 455 PHE n 
3 456 THR n 
3 457 ILE n 
3 458 SER n 
3 459 ARG n 
3 460 ASP n 
3 461 ASN n 
3 462 ALA n 
3 463 LYS n 
3 464 ASN n 
3 465 THR n 
3 466 VAL n 
3 467 TYR n 
3 468 LEU n 
3 469 GLU n 
3 470 MET n 
3 471 ASN n 
3 472 ASN n 
3 473 LEU n 
3 474 LYS n 
3 475 PRO n 
3 476 GLU n 
3 477 ASP n 
3 478 THR n 
3 479 ALA n 
3 480 VAL n 
3 481 TYR n 
3 482 TYR n 
3 483 CYS n 
3 484 ALA n 
3 485 ALA n 
3 486 LYS n 
3 487 GLY n 
3 488 ARG n 
3 489 TYR n 
3 490 SER n 
3 491 GLY n 
3 492 GLY n 
3 493 LEU n 
3 494 TYR n 
3 495 TYR n 
3 496 PRO n 
3 497 THR n 
3 498 ASN n 
3 499 TYR n 
3 500 ASP n 
3 501 TYR n 
3 502 TRP n 
3 503 GLY n 
3 504 GLN n 
3 505 GLY n 
3 506 THR n 
3 507 GLN n 
3 508 VAL n 
3 509 THR n 
3 510 VAL n 
3 511 SER n 
3 512 SER n 
3 513 HIS n 
3 514 HIS n 
3 515 HIS n 
3 516 HIS n 
3 517 HIS n 
3 518 HIS n 
3 519 GLU n 
3 520 PRO n 
3 521 GLU n 
3 522 ALA n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   365 human ? GABRA1             ? ? ? ? ? ? 'Homo sapiens'            9606   ? ? ? ? ? ? ? ? 
'Homo sapiens'     9606 ? ? ? ? ? ? ?         ? 'EXPI 293F' ? ? ? ? ? ? ? ? ? pHLSec ? ? 
1 2 sample 'Biological sequence' 366 411 human ? GABRA1             ? ? ? ? ? ? 'Homo sapiens'            9606   ? ? ? ? ? ? ? ? 
'Homo sapiens'     9606 ? ? ? ? ? ? ?         ? 'EXPI 293F' ? ? ? ? ? ? ? ? ? pHLSec ? ? 
2 1 sample 'Biological sequence' 1   361 human ? GABRB3             ? ? ? ? ? ? 'Homo sapiens'            9606   ? ? ? ? ? ? ? ? 
'Homo sapiens'     9606 ? ? ? ? ? ? ?         ? 'EXPI 293F' ? ? ? ? ? ? ? ? ? pHLSec ? ? 
2 2 sample 'Biological sequence' 362 395 human ? GABRB3             ? ? ? ? ? ? 'Homo sapiens'            9606   ? ? ? ? ? ? ? ? 
'Homo sapiens'     9606 ? ? ? ? ? ? ?         ? 'EXPI 293F' ? ? ? ? ? ? ? ? ? pHLSec ? ? 
3 1 sample 'Biological sequence' 1   12  ?     ? ?                  ? ? ? ? ? ? 'Lama glama'              9844   ? ? ? ? ? ? ? ? 
'Escherichia coli' 562  ? ? ? ? ? ? 'WK6 su-' ? ?           ? ? ? ? ? ? ? ? ? ?      ? ? 
3 2 sample 'Biological sequence' 13  233 ?     ? 'hopQ, HPG27_1120' ? ? ? ? ? ? 'Helicobacter pylori G27' 563041 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562  ? ? ? ? ? ? 'WK6 su-' ? ?           ? ? ? ? ? ? ? ? ? ?      ? ? 
3 3 sample 'Biological sequence' 234 402 ?     ? 'hopQ, HPG27_1120' ? ? ? ? ? ? 'Helicobacter pylori G27' 563041 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562  ? ? ? ? ? ? 'WK6 su-' ? ?           ? ? ? ? ? ? ? ? ? ?      ? ? 
3 4 sample 'Biological sequence' 403 522 ?     ? ?                  ? ? ? ? ? ? 'Lama glama'              9844   ? ? ? ? ? ? ? ? 
'Escherichia coli' 562  ? ? ? ? ? ? 'WK6 su-' ? ?           ? ? ? ? ? ? ? ? ? ?      ? ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
4 oligosaccharide 
5 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 4 'DManpa1-3[DManpa1-6]DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROH'                                                   
'Glycam Condensed Sequence' GMML       1.0   
2 4 'WURCS=2.0/3,5,4/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3/a4-b1_b4-c1_c3-d1_c6-e1' WURCS PDB2Glycan 
1.1.0 
3 4 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{}}}}'    LINUCS PDB-CARE   
?     
4 5 DGlcpNAcb1-4DGlcpNAcb1-ROH                                                                                  
'Glycam Condensed Sequence' GMML       1.0   
5 5 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1'                                                       WURCS PDB2Glycan 
1.1.0 
6 5 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'                                                             LINUCS PDB-CARE   
?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 4 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 4 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
3 4 4 MAN C1 O1 3 BMA O3 HO3 sing ? 
4 4 5 MAN C1 O1 3 BMA O6 HO6 sing ? 
5 5 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ABU non-polymer                   . 'GAMMA-AMINO-BUTANOIC ACID'              'GAMMA(AMINO)-BUTYRIC ACID' 'C4 H9 N O2'     103.120 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CL  non-polymer                   . 'CHLORIDE ION'                           ? 'Cl -1'          35.453  
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose                    'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6' 
180.156 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                         
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose              
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                       
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -52 ?   ?   ?   D . n 
A 1 2   ASP 2   -51 ?   ?   ?   D . n 
A 1 3   GLU 3   -50 ?   ?   ?   D . n 
A 1 4   LYS 4   -49 ?   ?   ?   D . n 
A 1 5   THR 5   -48 ?   ?   ?   D . n 
A 1 6   THR 6   -47 ?   ?   ?   D . n 
A 1 7   GLY 7   -46 ?   ?   ?   D . n 
A 1 8   TRP 8   -45 ?   ?   ?   D . n 
A 1 9   ARG 9   -44 ?   ?   ?   D . n 
A 1 10  GLY 10  -43 ?   ?   ?   D . n 
A 1 11  GLY 11  -42 ?   ?   ?   D . n 
A 1 12  HIS 12  -41 ?   ?   ?   D . n 
A 1 13  VAL 13  -40 ?   ?   ?   D . n 
A 1 14  VAL 14  -39 ?   ?   ?   D . n 
A 1 15  GLU 15  -38 ?   ?   ?   D . n 
A 1 16  GLY 16  -37 ?   ?   ?   D . n 
A 1 17  LEU 17  -36 ?   ?   ?   D . n 
A 1 18  ALA 18  -35 ?   ?   ?   D . n 
A 1 19  GLY 19  -34 ?   ?   ?   D . n 
A 1 20  GLU 20  -33 ?   ?   ?   D . n 
A 1 21  LEU 21  -32 ?   ?   ?   D . n 
A 1 22  GLU 22  -31 ?   ?   ?   D . n 
A 1 23  GLN 23  -30 ?   ?   ?   D . n 
A 1 24  LEU 24  -29 ?   ?   ?   D . n 
A 1 25  ARG 25  -28 ?   ?   ?   D . n 
A 1 26  ALA 26  -27 ?   ?   ?   D . n 
A 1 27  ARG 27  -26 ?   ?   ?   D . n 
A 1 28  LEU 28  -25 ?   ?   ?   D . n 
A 1 29  GLU 29  -24 ?   ?   ?   D . n 
A 1 30  HIS 30  -23 ?   ?   ?   D . n 
A 1 31  HIS 31  -22 ?   ?   ?   D . n 
A 1 32  PRO 32  -21 ?   ?   ?   D . n 
A 1 33  GLN 33  -20 ?   ?   ?   D . n 
A 1 34  GLY 34  -19 ?   ?   ?   D . n 
A 1 35  GLN 35  -18 ?   ?   ?   D . n 
A 1 36  ARG 36  -17 ?   ?   ?   D . n 
A 1 37  GLU 37  -16 ?   ?   ?   D . n 
A 1 38  PRO 38  -15 ?   ?   ?   D . n 
A 1 39  ASP 39  -14 ?   ?   ?   D . n 
A 1 40  TYR 40  -13 ?   ?   ?   D . n 
A 1 41  ASP 41  -12 ?   ?   ?   D . n 
A 1 42  ILE 42  -11 ?   ?   ?   D . n 
A 1 43  PRO 43  -10 ?   ?   ?   D . n 
A 1 44  THR 44  -9  ?   ?   ?   D . n 
A 1 45  THR 45  -8  ?   ?   ?   D . n 
A 1 46  GLU 46  -7  ?   ?   ?   D . n 
A 1 47  ASN 47  -6  ?   ?   ?   D . n 
A 1 48  LEU 48  -5  ?   ?   ?   D . n 
A 1 49  TYR 49  -4  ?   ?   ?   D . n 
A 1 50  PHE 50  -3  ?   ?   ?   D . n 
A 1 51  GLN 51  -2  ?   ?   ?   D . n 
A 1 52  GLY 52  -1  ?   ?   ?   D . n 
A 1 53  THR 53  0   ?   ?   ?   D . n 
A 1 54  GLY 54  1   ?   ?   ?   D . n 
A 1 55  GLN 55  2   ?   ?   ?   D . n 
A 1 56  PRO 56  3   ?   ?   ?   D . n 
A 1 57  SER 57  4   ?   ?   ?   D . n 
A 1 58  GLN 58  5   ?   ?   ?   D . n 
A 1 59  ASP 59  6   ?   ?   ?   D . n 
A 1 60  GLU 60  7   ?   ?   ?   D . n 
A 1 61  LEU 61  8   ?   ?   ?   D . n 
A 1 62  LYS 62  9   ?   ?   ?   D . n 
A 1 63  ASP 63  10  ?   ?   ?   D . n 
A 1 64  ASN 64  11  ?   ?   ?   D . n 
A 1 65  THR 65  12  12  THR THR D . n 
A 1 66  THR 66  13  13  THR THR D . n 
A 1 67  VAL 67  14  14  VAL VAL D . n 
A 1 68  PHE 68  15  15  PHE PHE D . n 
A 1 69  THR 69  16  16  THR THR D . n 
A 1 70  ARG 70  17  17  ARG ARG D . n 
A 1 71  ILE 71  18  18  ILE ILE D . n 
A 1 72  LEU 72  19  19  LEU LEU D . n 
A 1 73  ASP 73  20  20  ASP ASP D . n 
A 1 74  ARG 74  21  21  ARG ARG D . n 
A 1 75  LEU 75  22  22  LEU LEU D . n 
A 1 76  LEU 76  23  23  LEU LEU D . n 
A 1 77  ASP 77  24  24  ASP ASP D . n 
A 1 78  GLY 78  25  25  GLY GLY D . n 
A 1 79  TYR 79  26  26  TYR TYR D . n 
A 1 80  ASP 80  27  27  ASP ASP D . n 
A 1 81  ASN 81  28  28  ASN ASN D . n 
A 1 82  ARG 82  29  29  ARG ARG D . n 
A 1 83  LEU 83  30  30  LEU LEU D . n 
A 1 84  ARG 84  31  31  ARG ARG D . n 
A 1 85  PRO 85  32  32  PRO PRO D . n 
A 1 86  GLY 86  33  33  GLY GLY D . n 
A 1 87  LEU 87  34  34  LEU LEU D . n 
A 1 88  GLY 88  35  35  GLY GLY D . n 
A 1 89  GLU 89  36  36  GLU GLU D . n 
A 1 90  ARG 90  37  37  ARG ARG D . n 
A 1 91  VAL 91  38  38  VAL VAL D . n 
A 1 92  THR 92  39  39  THR THR D . n 
A 1 93  GLU 93  40  40  GLU GLU D . n 
A 1 94  VAL 94  41  41  VAL VAL D . n 
A 1 95  LYS 95  42  42  LYS LYS D . n 
A 1 96  THR 96  43  43  THR THR D . n 
A 1 97  ASP 97  44  44  ASP ASP D . n 
A 1 98  ILE 98  45  45  ILE ILE D . n 
A 1 99  PHE 99  46  46  PHE PHE D . n 
A 1 100 VAL 100 47  47  VAL VAL D . n 
A 1 101 THR 101 48  48  THR THR D . n 
A 1 102 SER 102 49  49  SER SER D . n 
A 1 103 PHE 103 50  50  PHE PHE D . n 
A 1 104 GLY 104 51  51  GLY GLY D . n 
A 1 105 PRO 105 52  52  PRO PRO D . n 
A 1 106 VAL 106 53  53  VAL VAL D . n 
A 1 107 SER 107 54  54  SER SER D . n 
A 1 108 ASP 108 55  55  ASP ASP D . n 
A 1 109 HIS 109 56  56  HIS HIS D . n 
A 1 110 ASP 110 57  57  ASP ASP D . n 
A 1 111 MET 111 58  58  MET MET D . n 
A 1 112 GLU 112 59  59  GLU GLU D . n 
A 1 113 TYR 113 60  60  TYR TYR D . n 
A 1 114 THR 114 61  61  THR THR D . n 
A 1 115 ILE 115 62  62  ILE ILE D . n 
A 1 116 ASP 116 63  63  ASP ASP D . n 
A 1 117 VAL 117 64  64  VAL VAL D . n 
A 1 118 PHE 118 65  65  PHE PHE D . n 
A 1 119 PHE 119 66  66  PHE PHE D . n 
A 1 120 ARG 120 67  67  ARG ARG D . n 
A 1 121 GLN 121 68  68  GLN GLN D . n 
A 1 122 SER 122 69  69  SER SER D . n 
A 1 123 TRP 123 70  70  TRP TRP D . n 
A 1 124 LYS 124 71  71  LYS LYS D . n 
A 1 125 ASP 125 72  72  ASP ASP D . n 
A 1 126 GLU 126 73  73  GLU GLU D . n 
A 1 127 ARG 127 74  74  ARG ARG D . n 
A 1 128 LEU 128 75  75  LEU LEU D . n 
A 1 129 LYS 129 76  76  LYS LYS D . n 
A 1 130 PHE 130 77  77  PHE PHE D . n 
A 1 131 LYS 131 78  78  LYS LYS D . n 
A 1 132 GLY 132 79  79  GLY GLY D . n 
A 1 133 PRO 133 80  80  PRO PRO D . n 
A 1 134 MET 134 81  81  MET MET D . n 
A 1 135 THR 135 82  82  THR THR D . n 
A 1 136 VAL 136 83  83  VAL VAL D . n 
A 1 137 LEU 137 84  84  LEU LEU D . n 
A 1 138 ARG 138 85  85  ARG ARG D . n 
A 1 139 LEU 139 86  86  LEU LEU D . n 
A 1 140 ASN 140 87  87  ASN ASN D . n 
A 1 141 ASN 141 88  88  ASN ASN D . n 
A 1 142 LEU 142 89  89  LEU LEU D . n 
A 1 143 MET 143 90  90  MET MET D . n 
A 1 144 ALA 144 91  91  ALA ALA D . n 
A 1 145 SER 145 92  92  SER SER D . n 
A 1 146 LYS 146 93  93  LYS LYS D . n 
A 1 147 ILE 147 94  94  ILE ILE D . n 
A 1 148 TRP 148 95  95  TRP TRP D . n 
A 1 149 THR 149 96  96  THR THR D . n 
A 1 150 PRO 150 97  97  PRO PRO D . n 
A 1 151 ASP 151 98  98  ASP ASP D . n 
A 1 152 THR 152 99  99  THR THR D . n 
A 1 153 PHE 153 100 100 PHE PHE D . n 
A 1 154 PHE 154 101 101 PHE PHE D . n 
A 1 155 HIS 155 102 102 HIS HIS D . n 
A 1 156 ASN 156 103 103 ASN ASN D . n 
A 1 157 GLY 157 104 104 GLY GLY D . n 
A 1 158 LYS 158 105 105 LYS LYS D . n 
A 1 159 LYS 159 106 106 LYS LYS D . n 
A 1 160 SER 160 107 107 SER SER D . n 
A 1 161 VAL 161 108 108 VAL VAL D . n 
A 1 162 ALA 162 109 109 ALA ALA D . n 
A 1 163 HIS 163 110 110 HIS HIS D . n 
A 1 164 ASN 164 111 111 ASN ASN D . n 
A 1 165 MET 165 112 112 MET MET D . n 
A 1 166 THR 166 113 113 THR THR D . n 
A 1 167 MET 167 114 114 MET MET D . n 
A 1 168 PRO 168 115 115 PRO PRO D . n 
A 1 169 ASN 169 116 116 ASN ASN D . n 
A 1 170 LYS 170 117 117 LYS LYS D . n 
A 1 171 LEU 171 118 118 LEU LEU D . n 
A 1 172 LEU 172 119 119 LEU LEU D . n 
A 1 173 ARG 173 120 120 ARG ARG D . n 
A 1 174 ILE 174 121 121 ILE ILE D . n 
A 1 175 THR 175 122 122 THR THR D . n 
A 1 176 GLU 176 123 123 GLU GLU D . n 
A 1 177 ASP 177 124 124 ASP ASP D . n 
A 1 178 GLY 178 125 125 GLY GLY D . n 
A 1 179 THR 179 126 126 THR THR D . n 
A 1 180 LEU 180 127 127 LEU LEU D . n 
A 1 181 LEU 181 128 128 LEU LEU D . n 
A 1 182 TYR 182 129 129 TYR TYR D . n 
A 1 183 THR 183 130 130 THR THR D . n 
A 1 184 MET 184 131 131 MET MET D . n 
A 1 185 ARG 185 132 132 ARG ARG D . n 
A 1 186 LEU 186 133 133 LEU LEU D . n 
A 1 187 THR 187 134 134 THR THR D . n 
A 1 188 VAL 188 135 135 VAL VAL D . n 
A 1 189 ARG 189 136 136 ARG ARG D . n 
A 1 190 ALA 190 137 137 ALA ALA D . n 
A 1 191 GLU 191 138 138 GLU GLU D . n 
A 1 192 CYS 192 139 139 CYS CYS D . n 
A 1 193 PRO 193 140 140 PRO PRO D . n 
A 1 194 MET 194 141 141 MET MET D . n 
A 1 195 HIS 195 142 142 HIS HIS D . n 
A 1 196 LEU 196 143 143 LEU LEU D . n 
A 1 197 GLU 197 144 144 GLU GLU D . n 
A 1 198 ASP 198 145 145 ASP ASP D . n 
A 1 199 PHE 199 146 146 PHE PHE D . n 
A 1 200 PRO 200 147 147 PRO PRO D . n 
A 1 201 MET 201 148 148 MET MET D . n 
A 1 202 ASP 202 149 149 ASP ASP D . n 
A 1 203 ALA 203 150 150 ALA ALA D . n 
A 1 204 HIS 204 151 151 HIS HIS D . n 
A 1 205 ALA 205 152 152 ALA ALA D . n 
A 1 206 CYS 206 153 153 CYS CYS D . n 
A 1 207 PRO 207 154 154 PRO PRO D . n 
A 1 208 LEU 208 155 155 LEU LEU D . n 
A 1 209 LYS 209 156 156 LYS LYS D . n 
A 1 210 PHE 210 157 157 PHE PHE D . n 
A 1 211 GLY 211 158 158 GLY GLY D . n 
A 1 212 SER 212 159 159 SER SER D . n 
A 1 213 TYR 213 160 160 TYR TYR D . n 
A 1 214 ALA 214 161 161 ALA ALA D . n 
A 1 215 TYR 215 162 162 TYR TYR D . n 
A 1 216 THR 216 163 163 THR THR D . n 
A 1 217 ARG 217 164 164 ARG ARG D . n 
A 1 218 ALA 218 165 165 ALA ALA D . n 
A 1 219 GLU 219 166 166 GLU GLU D . n 
A 1 220 VAL 220 167 167 VAL VAL D . n 
A 1 221 VAL 221 168 168 VAL VAL D . n 
A 1 222 TYR 222 169 169 TYR TYR D . n 
A 1 223 GLU 223 170 170 GLU GLU D . n 
A 1 224 TRP 224 171 171 TRP TRP D . n 
A 1 225 THR 225 172 172 THR THR D . n 
A 1 226 ARG 226 173 173 ARG ARG D . n 
A 1 227 GLU 227 174 174 GLU GLU D . n 
A 1 228 PRO 228 175 175 PRO PRO D . n 
A 1 229 ALA 229 176 176 ALA ALA D . n 
A 1 230 ARG 230 177 177 ARG ARG D . n 
A 1 231 SER 231 178 178 SER SER D . n 
A 1 232 VAL 232 179 179 VAL VAL D . n 
A 1 233 VAL 233 180 180 VAL VAL D . n 
A 1 234 VAL 234 181 181 VAL VAL D . n 
A 1 235 ALA 235 182 182 ALA ALA D . n 
A 1 236 GLU 236 183 183 GLU GLU D . n 
A 1 237 ASP 237 184 184 ASP ASP D . n 
A 1 238 GLY 238 185 185 GLY GLY D . n 
A 1 239 SER 239 186 186 SER SER D . n 
A 1 240 ARG 240 187 187 ARG ARG D . n 
A 1 241 LEU 241 188 188 LEU LEU D . n 
A 1 242 ASN 242 189 189 ASN ASN D . n 
A 1 243 GLN 243 190 190 GLN GLN D . n 
A 1 244 TYR 244 191 191 TYR TYR D . n 
A 1 245 ASP 245 192 192 ASP ASP D . n 
A 1 246 LEU 246 193 193 LEU LEU D . n 
A 1 247 LEU 247 194 194 LEU LEU D . n 
A 1 248 GLY 248 195 195 GLY GLY D . n 
A 1 249 GLN 249 196 196 GLN GLN D . n 
A 1 250 THR 250 197 197 THR THR D . n 
A 1 251 VAL 251 198 198 VAL VAL D . n 
A 1 252 ASP 252 199 199 ASP ASP D . n 
A 1 253 SER 253 200 200 SER SER D . n 
A 1 254 GLY 254 201 201 GLY GLY D . n 
A 1 255 ILE 255 202 202 ILE ILE D . n 
A 1 256 VAL 256 203 203 VAL VAL D . n 
A 1 257 GLN 257 204 204 GLN GLN D . n 
A 1 258 SER 258 205 205 SER SER D . n 
A 1 259 SER 259 206 206 SER SER D . n 
A 1 260 THR 260 207 207 THR THR D . n 
A 1 261 GLY 261 208 208 GLY GLY D . n 
A 1 262 GLU 262 209 209 GLU GLU D . n 
A 1 263 TYR 263 210 210 TYR TYR D . n 
A 1 264 VAL 264 211 211 VAL VAL D . n 
A 1 265 VAL 265 212 212 VAL VAL D . n 
A 1 266 MET 266 213 213 MET MET D . n 
A 1 267 THR 267 214 214 THR THR D . n 
A 1 268 THR 268 215 215 THR THR D . n 
A 1 269 HIS 269 216 216 HIS HIS D . n 
A 1 270 PHE 270 217 217 PHE PHE D . n 
A 1 271 HIS 271 218 218 HIS HIS D . n 
A 1 272 LEU 272 219 219 LEU LEU D . n 
A 1 273 LYS 273 220 220 LYS LYS D . n 
A 1 274 ARG 274 221 221 ARG ARG D . n 
A 1 275 LYS 275 222 222 LYS LYS D . n 
A 1 276 ILE 276 223 223 ILE ILE D . n 
A 1 277 GLY 277 224 224 GLY GLY D . n 
A 1 278 TYR 278 225 225 TYR TYR D . n 
A 1 279 PHE 279 226 226 PHE PHE D . n 
A 1 280 VAL 280 227 227 VAL VAL D . n 
A 1 281 ILE 281 228 228 ILE ILE D . n 
A 1 282 GLN 282 229 229 GLN GLN D . n 
A 1 283 THR 283 230 230 THR THR D . n 
A 1 284 TYR 284 231 231 TYR TYR D . n 
A 1 285 LEU 285 232 232 LEU LEU D . n 
A 1 286 PRO 286 233 233 PRO PRO D . n 
A 1 287 CYS 287 234 234 CYS CYS D . n 
A 1 288 ILE 288 235 235 ILE ILE D . n 
A 1 289 MET 289 236 236 MET MET D . n 
A 1 290 THR 290 237 237 THR THR D . n 
A 1 291 VAL 291 238 238 VAL VAL D . n 
A 1 292 ILE 292 239 239 ILE ILE D . n 
A 1 293 LEU 293 240 240 LEU LEU D . n 
A 1 294 SER 294 241 241 SER SER D . n 
A 1 295 GLN 295 242 242 GLN GLN D . n 
A 1 296 VAL 296 243 243 VAL VAL D . n 
A 1 297 SER 297 244 244 SER SER D . n 
A 1 298 PHE 298 245 245 PHE PHE D . n 
A 1 299 TRP 299 246 246 TRP TRP D . n 
A 1 300 LEU 300 247 247 LEU LEU D . n 
A 1 301 ASN 301 248 248 ASN ASN D . n 
A 1 302 ARG 302 249 249 ARG ARG D . n 
A 1 303 GLU 303 250 250 GLU GLU D . n 
A 1 304 SER 304 251 251 SER SER D . n 
A 1 305 VAL 305 252 252 VAL VAL D . n 
A 1 306 PRO 306 253 253 PRO PRO D . n 
A 1 307 ALA 307 254 254 ALA ALA D . n 
A 1 308 ARG 308 255 255 ARG ARG D . n 
A 1 309 THR 309 256 256 THR THR D . n 
A 1 310 VAL 310 257 257 VAL VAL D . n 
A 1 311 PHE 311 258 258 PHE PHE D . n 
A 1 312 GLY 312 259 259 GLY GLY D . n 
A 1 313 VAL 313 260 260 VAL VAL D . n 
A 1 314 THR 314 261 261 THR THR D . n 
A 1 315 THR 315 262 262 THR THR D . n 
A 1 316 VAL 316 263 263 VAL VAL D . n 
A 1 317 LEU 317 264 264 LEU LEU D . n 
A 1 318 THR 318 265 265 THR THR D . n 
A 1 319 MET 319 266 266 MET MET D . n 
A 1 320 THR 320 267 267 THR THR D . n 
A 1 321 THR 321 268 268 THR THR D . n 
A 1 322 LEU 322 269 269 LEU LEU D . n 
A 1 323 SER 323 270 270 SER SER D . n 
A 1 324 ILE 324 271 271 ILE ILE D . n 
A 1 325 SER 325 272 272 SER SER D . n 
A 1 326 ALA 326 273 273 ALA ALA D . n 
A 1 327 ARG 327 274 274 ARG ARG D . n 
A 1 328 ASN 328 275 275 ASN ASN D . n 
A 1 329 SER 329 276 276 SER SER D . n 
A 1 330 LEU 330 277 277 LEU LEU D . n 
A 1 331 PRO 331 278 278 PRO PRO D . n 
A 1 332 LYS 332 279 279 LYS LYS D . n 
A 1 333 VAL 333 280 280 VAL VAL D . n 
A 1 334 ALA 334 281 281 ALA ALA D . n 
A 1 335 TYR 335 282 282 TYR TYR D . n 
A 1 336 ALA 336 283 283 ALA ALA D . n 
A 1 337 THR 337 284 284 THR THR D . n 
A 1 338 ALA 338 285 285 ALA ALA D . n 
A 1 339 MET 339 286 286 MET MET D . n 
A 1 340 ASP 340 287 287 ASP ASP D . n 
A 1 341 TRP 341 288 288 TRP TRP D . n 
A 1 342 PHE 342 289 289 PHE PHE D . n 
A 1 343 ILE 343 290 290 ILE ILE D . n 
A 1 344 ALA 344 291 291 ALA ALA D . n 
A 1 345 VAL 345 292 292 VAL VAL D . n 
A 1 346 CYS 346 293 293 CYS CYS D . n 
A 1 347 TYR 347 294 294 TYR TYR D . n 
A 1 348 ALA 348 295 295 ALA ALA D . n 
A 1 349 PHE 349 296 296 PHE PHE D . n 
A 1 350 VAL 350 297 297 VAL VAL D . n 
A 1 351 PHE 351 298 298 PHE PHE D . n 
A 1 352 SER 352 299 299 SER SER D . n 
A 1 353 ALA 353 300 300 ALA ALA D . n 
A 1 354 LEU 354 301 301 LEU LEU D . n 
A 1 355 ILE 355 302 302 ILE ILE D . n 
A 1 356 GLU 356 303 303 GLU GLU D . n 
A 1 357 PHE 357 304 304 PHE PHE D . n 
A 1 358 ALA 358 305 305 ALA ALA D . n 
A 1 359 THR 359 306 306 THR THR D . n 
A 1 360 VAL 360 307 307 VAL VAL D . n 
A 1 361 ASN 361 308 308 ASN ASN D . n 
A 1 362 TYR 362 309 309 TYR TYR D . n 
A 1 363 PHE 363 310 310 PHE PHE D . n 
A 1 364 THR 364 311 311 THR THR D . n 
A 1 365 LYS 365 312 312 LYS LYS D . n 
A 1 366 SER 366 313 313 SER SER D . n 
A 1 367 GLN 367 385 385 GLN GLN D . n 
A 1 368 PRO 368 386 386 PRO PRO D . n 
A 1 369 ALA 369 387 387 ALA ALA D . n 
A 1 370 ARG 370 388 388 ARG ARG D . n 
A 1 371 ALA 371 389 389 ALA ALA D . n 
A 1 372 ALA 372 390 390 ALA ALA D . n 
A 1 373 LYS 373 391 391 LYS LYS D . n 
A 1 374 ILE 374 392 392 ILE ILE D . n 
A 1 375 ASP 375 393 393 ASP ASP D . n 
A 1 376 ARG 376 394 394 ARG ARG D . n 
A 1 377 LEU 377 395 395 LEU LEU D . n 
A 1 378 SER 378 396 396 SER SER D . n 
A 1 379 ARG 379 397 397 ARG ARG D . n 
A 1 380 ILE 380 398 398 ILE ILE D . n 
A 1 381 ALA 381 399 399 ALA ALA D . n 
A 1 382 PHE 382 400 400 PHE PHE D . n 
A 1 383 PRO 383 401 401 PRO PRO D . n 
A 1 384 LEU 384 402 402 LEU LEU D . n 
A 1 385 LEU 385 403 403 LEU LEU D . n 
A 1 386 PHE 386 404 404 PHE PHE D . n 
A 1 387 GLY 387 405 405 GLY GLY D . n 
A 1 388 ILE 388 406 406 ILE ILE D . n 
A 1 389 PHE 389 407 407 PHE PHE D . n 
A 1 390 ASN 390 408 408 ASN ASN D . n 
A 1 391 LEU 391 409 409 LEU LEU D . n 
A 1 392 VAL 392 410 410 VAL VAL D . n 
A 1 393 TYR 393 411 411 TYR TYR D . n 
A 1 394 TRP 394 412 412 TRP TRP D . n 
A 1 395 ALA 395 413 413 ALA ALA D . n 
A 1 396 THR 396 414 414 THR THR D . n 
A 1 397 TYR 397 415 415 TYR TYR D . n 
A 1 398 LEU 398 416 416 LEU LEU D . n 
A 1 399 ASN 399 417 417 ASN ASN D . n 
A 1 400 ARG 400 418 418 ARG ARG D . n 
A 1 401 GLU 401 419 ?   ?   ?   D . n 
A 1 402 PRO 402 420 ?   ?   ?   D . n 
A 1 403 GLN 403 421 ?   ?   ?   D . n 
A 1 404 LEU 404 422 ?   ?   ?   D . n 
A 1 405 LYS 405 423 ?   ?   ?   D . n 
A 1 406 ALA 406 424 ?   ?   ?   D . n 
A 1 407 PRO 407 425 ?   ?   ?   D . n 
A 1 408 THR 408 426 ?   ?   ?   D . n 
A 1 409 PRO 409 427 ?   ?   ?   D . n 
A 1 410 HIS 410 428 ?   ?   ?   D . n 
A 1 411 GLN 411 429 ?   ?   ?   D . n 
B 2 1   MET 1   -53 ?   ?   ?   E . n 
B 2 2   ASP 2   -52 ?   ?   ?   E . n 
B 2 3   GLU 3   -51 ?   ?   ?   E . n 
B 2 4   LYS 4   -50 ?   ?   ?   E . n 
B 2 5   THR 5   -49 ?   ?   ?   E . n 
B 2 6   THR 6   -48 ?   ?   ?   E . n 
B 2 7   GLY 7   -47 ?   ?   ?   E . n 
B 2 8   TRP 8   -46 ?   ?   ?   E . n 
B 2 9   ARG 9   -45 ?   ?   ?   E . n 
B 2 10  GLY 10  -44 ?   ?   ?   E . n 
B 2 11  GLY 11  -43 ?   ?   ?   E . n 
B 2 12  HIS 12  -42 ?   ?   ?   E . n 
B 2 13  VAL 13  -41 ?   ?   ?   E . n 
B 2 14  VAL 14  -40 ?   ?   ?   E . n 
B 2 15  GLU 15  -39 ?   ?   ?   E . n 
B 2 16  GLY 16  -38 ?   ?   ?   E . n 
B 2 17  LEU 17  -37 ?   ?   ?   E . n 
B 2 18  ALA 18  -36 ?   ?   ?   E . n 
B 2 19  GLY 19  -35 ?   ?   ?   E . n 
B 2 20  GLU 20  -34 ?   ?   ?   E . n 
B 2 21  LEU 21  -33 ?   ?   ?   E . n 
B 2 22  GLU 22  -32 ?   ?   ?   E . n 
B 2 23  GLN 23  -31 ?   ?   ?   E . n 
B 2 24  LEU 24  -30 ?   ?   ?   E . n 
B 2 25  ARG 25  -29 ?   ?   ?   E . n 
B 2 26  ALA 26  -28 ?   ?   ?   E . n 
B 2 27  ARG 27  -27 ?   ?   ?   E . n 
B 2 28  LEU 28  -26 ?   ?   ?   E . n 
B 2 29  GLU 29  -25 ?   ?   ?   E . n 
B 2 30  HIS 30  -24 ?   ?   ?   E . n 
B 2 31  HIS 31  -23 ?   ?   ?   E . n 
B 2 32  PRO 32  -22 ?   ?   ?   E . n 
B 2 33  GLN 33  -21 ?   ?   ?   E . n 
B 2 34  GLY 34  -20 ?   ?   ?   E . n 
B 2 35  GLN 35  -19 ?   ?   ?   E . n 
B 2 36  ARG 36  -18 ?   ?   ?   E . n 
B 2 37  GLU 37  -17 ?   ?   ?   E . n 
B 2 38  PRO 38  -16 ?   ?   ?   E . n 
B 2 39  ASP 39  -15 ?   ?   ?   E . n 
B 2 40  TYR 40  -14 ?   ?   ?   E . n 
B 2 41  ASP 41  -13 ?   ?   ?   E . n 
B 2 42  ILE 42  -12 ?   ?   ?   E . n 
B 2 43  PRO 43  -11 ?   ?   ?   E . n 
B 2 44  THR 44  -10 ?   ?   ?   E . n 
B 2 45  THR 45  -9  ?   ?   ?   E . n 
B 2 46  GLU 46  -8  ?   ?   ?   E . n 
B 2 47  ASN 47  -7  ?   ?   ?   E . n 
B 2 48  LEU 48  -6  ?   ?   ?   E . n 
B 2 49  TYR 49  -5  ?   ?   ?   E . n 
B 2 50  PHE 50  -4  ?   ?   ?   E . n 
B 2 51  GLN 51  -3  ?   ?   ?   E . n 
B 2 52  GLY 52  -2  ?   ?   ?   E . n 
B 2 53  THR 53  -1  ?   ?   ?   E . n 
B 2 54  GLY 54  0   ?   ?   ?   E . n 
B 2 55  GLN 55  1   ?   ?   ?   E . n 
B 2 56  SER 56  2   ?   ?   ?   E . n 
B 2 57  VAL 57  3   ?   ?   ?   E . n 
B 2 58  ASN 58  4   ?   ?   ?   E . n 
B 2 59  ASP 59  5   ?   ?   ?   E . n 
B 2 60  PRO 60  6   ?   ?   ?   E . n 
B 2 61  GLY 61  7   ?   ?   ?   E . n 
B 2 62  ASN 62  8   8   ASN ASN E . n 
B 2 63  MET 63  9   9   MET MET E . n 
B 2 64  SER 64  10  10  SER SER E . n 
B 2 65  PHE 65  11  11  PHE PHE E . n 
B 2 66  VAL 66  12  12  VAL VAL E . n 
B 2 67  LYS 67  13  13  LYS LYS E . n 
B 2 68  GLU 68  14  14  GLU GLU E . n 
B 2 69  THR 69  15  15  THR THR E . n 
B 2 70  VAL 70  16  16  VAL VAL E . n 
B 2 71  ASP 71  17  17  ASP ASP E . n 
B 2 72  LYS 72  18  18  LYS LYS E . n 
B 2 73  LEU 73  19  19  LEU LEU E . n 
B 2 74  LEU 74  20  20  LEU LEU E . n 
B 2 75  LYS 75  21  21  LYS LYS E . n 
B 2 76  GLY 76  22  22  GLY GLY E . n 
B 2 77  TYR 77  23  23  TYR TYR E . n 
B 2 78  ASP 78  24  24  ASP ASP E . n 
B 2 79  ILE 79  25  25  ILE ILE E . n 
B 2 80  ARG 80  26  26  ARG ARG E . n 
B 2 81  LEU 81  27  27  LEU LEU E . n 
B 2 82  ARG 82  28  28  ARG ARG E . n 
B 2 83  PRO 83  29  29  PRO PRO E . n 
B 2 84  ASP 84  30  30  ASP ASP E . n 
B 2 85  PHE 85  31  31  PHE PHE E . n 
B 2 86  GLY 86  32  32  GLY GLY E . n 
B 2 87  GLY 87  33  33  GLY GLY E . n 
B 2 88  PRO 88  34  34  PRO PRO E . n 
B 2 89  PRO 89  35  35  PRO PRO E . n 
B 2 90  VAL 90  36  36  VAL VAL E . n 
B 2 91  CYS 91  37  37  CYS CYS E . n 
B 2 92  VAL 92  38  38  VAL VAL E . n 
B 2 93  GLY 93  39  39  GLY GLY E . n 
B 2 94  MET 94  40  40  MET MET E . n 
B 2 95  ASN 95  41  41  ASN ASN E . n 
B 2 96  ILE 96  42  42  ILE ILE E . n 
B 2 97  ASP 97  43  43  ASP ASP E . n 
B 2 98  ILE 98  44  44  ILE ILE E . n 
B 2 99  ALA 99  45  45  ALA ALA E . n 
B 2 100 SER 100 46  46  SER SER E . n 
B 2 101 ILE 101 47  47  ILE ILE E . n 
B 2 102 ASP 102 48  48  ASP ASP E . n 
B 2 103 MET 103 49  49  MET MET E . n 
B 2 104 VAL 104 50  50  VAL VAL E . n 
B 2 105 SER 105 51  51  SER SER E . n 
B 2 106 GLU 106 52  52  GLU GLU E . n 
B 2 107 VAL 107 53  53  VAL VAL E . n 
B 2 108 ASN 108 54  54  ASN ASN E . n 
B 2 109 MET 109 55  55  MET MET E . n 
B 2 110 ASP 110 56  56  ASP ASP E . n 
B 2 111 TYR 111 57  57  TYR TYR E . n 
B 2 112 THR 112 58  58  THR THR E . n 
B 2 113 LEU 113 59  59  LEU LEU E . n 
B 2 114 THR 114 60  60  THR THR E . n 
B 2 115 MET 115 61  61  MET MET E . n 
B 2 116 TYR 116 62  62  TYR TYR E . n 
B 2 117 PHE 117 63  63  PHE PHE E . n 
B 2 118 GLN 118 64  64  GLN GLN E . n 
B 2 119 GLN 119 65  65  GLN GLN E . n 
B 2 120 TYR 120 66  66  TYR TYR E . n 
B 2 121 TRP 121 67  67  TRP TRP E . n 
B 2 122 ARG 122 68  68  ARG ARG E . n 
B 2 123 ASP 123 69  69  ASP ASP E . n 
B 2 124 LYS 124 70  70  LYS LYS E . n 
B 2 125 ARG 125 71  71  ARG ARG E . n 
B 2 126 LEU 126 72  72  LEU LEU E . n 
B 2 127 ALA 127 73  73  ALA ALA E . n 
B 2 128 TYR 128 74  74  TYR TYR E . n 
B 2 129 SER 129 75  75  SER SER E . n 
B 2 130 GLY 130 76  76  GLY GLY E . n 
B 2 131 ILE 131 77  77  ILE ILE E . n 
B 2 132 PRO 132 78  78  PRO PRO E . n 
B 2 133 LEU 133 79  79  LEU LEU E . n 
B 2 134 ASN 134 80  80  ASN ASN E . n 
B 2 135 LEU 135 81  81  LEU LEU E . n 
B 2 136 THR 136 82  82  THR THR E . n 
B 2 137 LEU 137 83  83  LEU LEU E . n 
B 2 138 ASP 138 84  84  ASP ASP E . n 
B 2 139 ASN 139 85  85  ASN ASN E . n 
B 2 140 ARG 140 86  86  ARG ARG E . n 
B 2 141 VAL 141 87  87  VAL VAL E . n 
B 2 142 ALA 142 88  88  ALA ALA E . n 
B 2 143 ASP 143 89  89  ASP ASP E . n 
B 2 144 GLN 144 90  90  GLN GLN E . n 
B 2 145 LEU 145 91  91  LEU LEU E . n 
B 2 146 TRP 146 92  92  TRP TRP E . n 
B 2 147 VAL 147 93  93  VAL VAL E . n 
B 2 148 PRO 148 94  94  PRO PRO E . n 
B 2 149 ASP 149 95  95  ASP ASP E . n 
B 2 150 THR 150 96  96  THR THR E . n 
B 2 151 TYR 151 97  97  TYR TYR E . n 
B 2 152 PHE 152 98  98  PHE PHE E . n 
B 2 153 LEU 153 99  99  LEU LEU E . n 
B 2 154 ASN 154 100 100 ASN ASN E . n 
B 2 155 ASP 155 101 101 ASP ASP E . n 
B 2 156 LYS 156 102 102 LYS LYS E . n 
B 2 157 LYS 157 103 103 LYS LYS E . n 
B 2 158 SER 158 104 104 SER SER E . n 
B 2 159 PHE 159 105 105 PHE PHE E . n 
B 2 160 VAL 160 106 106 VAL VAL E . n 
B 2 161 HIS 161 107 107 HIS HIS E . n 
B 2 162 GLY 162 108 108 GLY GLY E . n 
B 2 163 VAL 163 109 109 VAL VAL E . n 
B 2 164 THR 164 110 110 THR THR E . n 
B 2 165 VAL 165 111 111 VAL VAL E . n 
B 2 166 LYS 166 112 112 LYS LYS E . n 
B 2 167 ASN 167 113 113 ASN ASN E . n 
B 2 168 ARG 168 114 114 ARG ARG E . n 
B 2 169 MET 169 115 115 MET MET E . n 
B 2 170 ILE 170 116 116 ILE ILE E . n 
B 2 171 ARG 171 117 117 ARG ARG E . n 
B 2 172 LEU 172 118 118 LEU LEU E . n 
B 2 173 HIS 173 119 119 HIS HIS E . n 
B 2 174 PRO 174 120 120 PRO PRO E . n 
B 2 175 ASP 175 121 121 ASP ASP E . n 
B 2 176 GLY 176 122 122 GLY GLY E . n 
B 2 177 THR 177 123 123 THR THR E . n 
B 2 178 VAL 178 124 124 VAL VAL E . n 
B 2 179 LEU 179 125 125 LEU LEU E . n 
B 2 180 TYR 180 126 126 TYR TYR E . n 
B 2 181 GLY 181 127 127 GLY GLY E . n 
B 2 182 LEU 182 128 128 LEU LEU E . n 
B 2 183 ARG 183 129 129 ARG ARG E . n 
B 2 184 ILE 184 130 130 ILE ILE E . n 
B 2 185 THR 185 131 131 THR THR E . n 
B 2 186 THR 186 132 132 THR THR E . n 
B 2 187 THR 187 133 133 THR THR E . n 
B 2 188 ALA 188 134 134 ALA ALA E . n 
B 2 189 ALA 189 135 135 ALA ALA E . n 
B 2 190 CYS 190 136 136 CYS CYS E . n 
B 2 191 MET 191 137 137 MET MET E . n 
B 2 192 MET 192 138 138 MET MET E . n 
B 2 193 ASP 193 139 139 ASP ASP E . n 
B 2 194 LEU 194 140 140 LEU LEU E . n 
B 2 195 ARG 195 141 141 ARG ARG E . n 
B 2 196 ARG 196 142 142 ARG ARG E . n 
B 2 197 TYR 197 143 143 TYR TYR E . n 
B 2 198 PRO 198 144 144 PRO PRO E . n 
B 2 199 LEU 199 145 145 LEU LEU E . n 
B 2 200 ASP 200 146 146 ASP ASP E . n 
B 2 201 GLU 201 147 147 GLU GLU E . n 
B 2 202 GLN 202 148 148 GLN GLN E . n 
B 2 203 ASN 203 149 149 ASN ASN E . n 
B 2 204 CYS 204 150 150 CYS CYS E . n 
B 2 205 THR 205 151 151 THR THR E . n 
B 2 206 LEU 206 152 152 LEU LEU E . n 
B 2 207 GLU 207 153 153 GLU GLU E . n 
B 2 208 ILE 208 154 154 ILE ILE E . n 
B 2 209 GLU 209 155 155 GLU GLU E . n 
B 2 210 SER 210 156 156 SER SER E . n 
B 2 211 TYR 211 157 157 TYR TYR E . n 
B 2 212 GLY 212 158 158 GLY GLY E . n 
B 2 213 TYR 213 159 159 TYR TYR E . n 
B 2 214 THR 214 160 160 THR THR E . n 
B 2 215 THR 215 161 161 THR THR E . n 
B 2 216 ASP 216 162 162 ASP ASP E . n 
B 2 217 ASP 217 163 163 ASP ASP E . n 
B 2 218 ILE 218 164 164 ILE ILE E . n 
B 2 219 GLU 219 165 165 GLU GLU E . n 
B 2 220 PHE 220 166 166 PHE PHE E . n 
B 2 221 TYR 221 167 167 TYR TYR E . n 
B 2 222 TRP 222 168 168 TRP TRP E . n 
B 2 223 ARG 223 169 169 ARG ARG E . n 
B 2 224 GLY 224 170 170 GLY GLY E . n 
B 2 225 GLY 225 171 171 GLY GLY E . n 
B 2 226 ASP 226 172 172 ASP ASP E . n 
B 2 227 LYS 227 173 173 LYS LYS E . n 
B 2 228 ALA 228 174 174 ALA ALA E . n 
B 2 229 VAL 229 175 175 VAL VAL E . n 
B 2 230 THR 230 176 176 THR THR E . n 
B 2 231 GLY 231 177 177 GLY GLY E . n 
B 2 232 VAL 232 178 178 VAL VAL E . n 
B 2 233 GLU 233 179 179 GLU GLU E . n 
B 2 234 ARG 234 180 180 ARG ARG E . n 
B 2 235 ILE 235 181 181 ILE ILE E . n 
B 2 236 GLU 236 182 182 GLU GLU E . n 
B 2 237 LEU 237 183 183 LEU LEU E . n 
B 2 238 PRO 238 184 184 PRO PRO E . n 
B 2 239 GLN 239 185 185 GLN GLN E . n 
B 2 240 PHE 240 186 186 PHE PHE E . n 
B 2 241 SER 241 187 187 SER SER E . n 
B 2 242 ILE 242 188 188 ILE ILE E . n 
B 2 243 VAL 243 189 189 VAL VAL E . n 
B 2 244 GLU 244 190 190 GLU GLU E . n 
B 2 245 HIS 245 191 191 HIS HIS E . n 
B 2 246 ARG 246 192 192 ARG ARG E . n 
B 2 247 LEU 247 193 193 LEU LEU E . n 
B 2 248 VAL 248 194 194 VAL VAL E . n 
B 2 249 SER 249 195 195 SER SER E . n 
B 2 250 ARG 250 196 196 ARG ARG E . n 
B 2 251 ASN 251 197 197 ASN ASN E . n 
B 2 252 VAL 252 198 198 VAL VAL E . n 
B 2 253 VAL 253 199 199 VAL VAL E . n 
B 2 254 PHE 254 200 200 PHE PHE E . n 
B 2 255 ALA 255 201 201 ALA ALA E . n 
B 2 256 THR 256 202 202 THR THR E . n 
B 2 257 GLY 257 203 203 GLY GLY E . n 
B 2 258 ALA 258 204 204 ALA ALA E . n 
B 2 259 TYR 259 205 205 TYR TYR E . n 
B 2 260 PRO 260 206 206 PRO PRO E . n 
B 2 261 ARG 261 207 207 ARG ARG E . n 
B 2 262 LEU 262 208 208 LEU LEU E . n 
B 2 263 SER 263 209 209 SER SER E . n 
B 2 264 LEU 264 210 210 LEU LEU E . n 
B 2 265 SER 265 211 211 SER SER E . n 
B 2 266 PHE 266 212 212 PHE PHE E . n 
B 2 267 ARG 267 213 213 ARG ARG E . n 
B 2 268 LEU 268 214 214 LEU LEU E . n 
B 2 269 LYS 269 215 215 LYS LYS E . n 
B 2 270 ARG 270 216 216 ARG ARG E . n 
B 2 271 ASN 271 217 217 ASN ASN E . n 
B 2 272 ILE 272 218 218 ILE ILE E . n 
B 2 273 GLY 273 219 219 GLY GLY E . n 
B 2 274 TYR 274 220 220 TYR TYR E . n 
B 2 275 PHE 275 221 221 PHE PHE E . n 
B 2 276 ILE 276 222 222 ILE ILE E . n 
B 2 277 LEU 277 223 223 LEU LEU E . n 
B 2 278 GLN 278 224 224 GLN GLN E . n 
B 2 279 THR 279 225 225 THR THR E . n 
B 2 280 TYR 280 226 226 TYR TYR E . n 
B 2 281 MET 281 227 227 MET MET E . n 
B 2 282 PRO 282 228 228 PRO PRO E . n 
B 2 283 SER 283 229 229 SER SER E . n 
B 2 284 ILE 284 230 230 ILE ILE E . n 
B 2 285 LEU 285 231 231 LEU LEU E . n 
B 2 286 ILE 286 232 232 ILE ILE E . n 
B 2 287 THR 287 233 233 THR THR E . n 
B 2 288 ILE 288 234 234 ILE ILE E . n 
B 2 289 LEU 289 235 235 LEU LEU E . n 
B 2 290 SER 290 236 236 SER SER E . n 
B 2 291 TRP 291 237 237 TRP TRP E . n 
B 2 292 VAL 292 238 238 VAL VAL E . n 
B 2 293 SER 293 239 239 SER SER E . n 
B 2 294 PHE 294 240 240 PHE PHE E . n 
B 2 295 TRP 295 241 241 TRP TRP E . n 
B 2 296 ILE 296 242 242 ILE ILE E . n 
B 2 297 ASN 297 243 243 ASN ASN E . n 
B 2 298 TYR 298 244 244 TYR TYR E . n 
B 2 299 ASP 299 245 245 ASP ASP E . n 
B 2 300 ALA 300 246 246 ALA ALA E . n 
B 2 301 SER 301 247 247 SER SER E . n 
B 2 302 ALA 302 248 248 ALA ALA E . n 
B 2 303 ALA 303 249 249 ALA ALA E . n 
B 2 304 ARG 304 250 250 ARG ARG E . n 
B 2 305 VAL 305 251 251 VAL VAL E . n 
B 2 306 ALA 306 252 252 ALA ALA E . n 
B 2 307 LEU 307 253 253 LEU LEU E . n 
B 2 308 GLY 308 254 254 GLY GLY E . n 
B 2 309 ILE 309 255 255 ILE ILE E . n 
B 2 310 THR 310 256 256 THR THR E . n 
B 2 311 THR 311 257 257 THR THR E . n 
B 2 312 VAL 312 258 258 VAL VAL E . n 
B 2 313 LEU 313 259 259 LEU LEU E . n 
B 2 314 THR 314 260 260 THR THR E . n 
B 2 315 MET 315 261 261 MET MET E . n 
B 2 316 THR 316 262 262 THR THR E . n 
B 2 317 THR 317 263 263 THR THR E . n 
B 2 318 ILE 318 264 264 ILE ILE E . n 
B 2 319 ASN 319 265 265 ASN ASN E . n 
B 2 320 THR 320 266 266 THR THR E . n 
B 2 321 HIS 321 267 267 HIS HIS E . n 
B 2 322 LEU 322 268 268 LEU LEU E . n 
B 2 323 ARG 323 269 269 ARG ARG E . n 
B 2 324 GLU 324 270 270 GLU GLU E . n 
B 2 325 THR 325 271 271 THR THR E . n 
B 2 326 LEU 326 272 272 LEU LEU E . n 
B 2 327 PRO 327 273 273 PRO PRO E . n 
B 2 328 LYS 328 274 274 LYS LYS E . n 
B 2 329 ILE 329 275 275 ILE ILE E . n 
B 2 330 PRO 330 276 276 PRO PRO E . n 
B 2 331 TYR 331 277 277 TYR TYR E . n 
B 2 332 VAL 332 278 278 VAL VAL E . n 
B 2 333 LYS 333 279 279 LYS LYS E . n 
B 2 334 ALA 334 280 280 ALA ALA E . n 
B 2 335 ILE 335 281 281 ILE ILE E . n 
B 2 336 ASP 336 282 282 ASP ASP E . n 
B 2 337 MET 337 283 283 MET MET E . n 
B 2 338 TYR 338 284 284 TYR TYR E . n 
B 2 339 LEU 339 285 285 LEU LEU E . n 
B 2 340 MET 340 286 286 MET MET E . n 
B 2 341 GLY 341 287 287 GLY GLY E . n 
B 2 342 CYS 342 288 288 CYS CYS E . n 
B 2 343 PHE 343 289 289 PHE PHE E . n 
B 2 344 VAL 344 290 290 VAL VAL E . n 
B 2 345 PHE 345 291 291 PHE PHE E . n 
B 2 346 VAL 346 292 292 VAL VAL E . n 
B 2 347 PHE 347 293 293 PHE PHE E . n 
B 2 348 LEU 348 294 294 LEU LEU E . n 
B 2 349 ALA 349 295 295 ALA ALA E . n 
B 2 350 LEU 350 296 296 LEU LEU E . n 
B 2 351 LEU 351 297 297 LEU LEU E . n 
B 2 352 GLU 352 298 298 GLU GLU E . n 
B 2 353 TYR 353 299 299 TYR TYR E . n 
B 2 354 ALA 354 300 300 ALA ALA E . n 
B 2 355 PHE 355 301 301 PHE PHE E . n 
B 2 356 VAL 356 302 302 VAL VAL E . n 
B 2 357 ASN 357 303 303 ASN ASN E . n 
B 2 358 TYR 358 304 304 TYR TYR E . n 
B 2 359 ILE 359 305 305 ILE ILE E . n 
B 2 360 PHE 360 306 306 PHE PHE E . n 
B 2 361 PHE 361 307 307 PHE PHE E . n 
B 2 362 SER 362 308 308 SER SER E . n 
B 2 363 GLN 363 309 309 GLN GLN E . n 
B 2 364 PRO 364 310 310 PRO PRO E . n 
B 2 365 ALA 365 311 311 ALA ALA E . n 
B 2 366 ARG 366 312 312 ARG ARG E . n 
B 2 367 ALA 367 313 313 ALA ALA E . n 
B 2 368 ALA 368 314 314 ALA ALA E . n 
B 2 369 ALA 369 422 422 ALA ALA E . n 
B 2 370 ILE 370 423 423 ILE ILE E . n 
B 2 371 ASP 371 424 424 ASP ASP E . n 
B 2 372 ARG 372 425 425 ARG ARG E . n 
B 2 373 TRP 373 426 426 TRP TRP E . n 
B 2 374 SER 374 427 427 SER SER E . n 
B 2 375 ARG 375 428 428 ARG ARG E . n 
B 2 376 ILE 376 429 429 ILE ILE E . n 
B 2 377 VAL 377 430 430 VAL VAL E . n 
B 2 378 PHE 378 431 431 PHE PHE E . n 
B 2 379 PRO 379 432 432 PRO PRO E . n 
B 2 380 PHE 380 433 433 PHE PHE E . n 
B 2 381 THR 381 434 434 THR THR E . n 
B 2 382 PHE 382 435 435 PHE PHE E . n 
B 2 383 SER 383 436 436 SER SER E . n 
B 2 384 LEU 384 437 437 LEU LEU E . n 
B 2 385 PHE 385 438 438 PHE PHE E . n 
B 2 386 ASN 386 439 439 ASN ASN E . n 
B 2 387 LEU 387 440 440 LEU LEU E . n 
B 2 388 VAL 388 441 441 VAL VAL E . n 
B 2 389 TYR 389 442 442 TYR TYR E . n 
B 2 390 TRP 390 443 443 TRP TRP E . n 
B 2 391 LEU 391 444 444 LEU LEU E . n 
B 2 392 TYR 392 445 445 TYR TYR E . n 
B 2 393 TYR 393 446 446 TYR TYR E . n 
B 2 394 VAL 394 447 447 VAL VAL E . n 
B 2 395 ASN 395 448 ?   ?   ?   E . n 
C 2 1   MET 1   -53 ?   ?   ?   B . n 
C 2 2   ASP 2   -52 ?   ?   ?   B . n 
C 2 3   GLU 3   -51 ?   ?   ?   B . n 
C 2 4   LYS 4   -50 ?   ?   ?   B . n 
C 2 5   THR 5   -49 ?   ?   ?   B . n 
C 2 6   THR 6   -48 ?   ?   ?   B . n 
C 2 7   GLY 7   -47 ?   ?   ?   B . n 
C 2 8   TRP 8   -46 ?   ?   ?   B . n 
C 2 9   ARG 9   -45 ?   ?   ?   B . n 
C 2 10  GLY 10  -44 ?   ?   ?   B . n 
C 2 11  GLY 11  -43 ?   ?   ?   B . n 
C 2 12  HIS 12  -42 ?   ?   ?   B . n 
C 2 13  VAL 13  -41 ?   ?   ?   B . n 
C 2 14  VAL 14  -40 ?   ?   ?   B . n 
C 2 15  GLU 15  -39 ?   ?   ?   B . n 
C 2 16  GLY 16  -38 ?   ?   ?   B . n 
C 2 17  LEU 17  -37 ?   ?   ?   B . n 
C 2 18  ALA 18  -36 ?   ?   ?   B . n 
C 2 19  GLY 19  -35 ?   ?   ?   B . n 
C 2 20  GLU 20  -34 ?   ?   ?   B . n 
C 2 21  LEU 21  -33 ?   ?   ?   B . n 
C 2 22  GLU 22  -32 ?   ?   ?   B . n 
C 2 23  GLN 23  -31 ?   ?   ?   B . n 
C 2 24  LEU 24  -30 ?   ?   ?   B . n 
C 2 25  ARG 25  -29 ?   ?   ?   B . n 
C 2 26  ALA 26  -28 ?   ?   ?   B . n 
C 2 27  ARG 27  -27 ?   ?   ?   B . n 
C 2 28  LEU 28  -26 ?   ?   ?   B . n 
C 2 29  GLU 29  -25 ?   ?   ?   B . n 
C 2 30  HIS 30  -24 ?   ?   ?   B . n 
C 2 31  HIS 31  -23 ?   ?   ?   B . n 
C 2 32  PRO 32  -22 ?   ?   ?   B . n 
C 2 33  GLN 33  -21 ?   ?   ?   B . n 
C 2 34  GLY 34  -20 ?   ?   ?   B . n 
C 2 35  GLN 35  -19 ?   ?   ?   B . n 
C 2 36  ARG 36  -18 ?   ?   ?   B . n 
C 2 37  GLU 37  -17 ?   ?   ?   B . n 
C 2 38  PRO 38  -16 ?   ?   ?   B . n 
C 2 39  ASP 39  -15 ?   ?   ?   B . n 
C 2 40  TYR 40  -14 ?   ?   ?   B . n 
C 2 41  ASP 41  -13 ?   ?   ?   B . n 
C 2 42  ILE 42  -12 ?   ?   ?   B . n 
C 2 43  PRO 43  -11 ?   ?   ?   B . n 
C 2 44  THR 44  -10 ?   ?   ?   B . n 
C 2 45  THR 45  -9  ?   ?   ?   B . n 
C 2 46  GLU 46  -8  ?   ?   ?   B . n 
C 2 47  ASN 47  -7  ?   ?   ?   B . n 
C 2 48  LEU 48  -6  ?   ?   ?   B . n 
C 2 49  TYR 49  -5  ?   ?   ?   B . n 
C 2 50  PHE 50  -4  ?   ?   ?   B . n 
C 2 51  GLN 51  -3  ?   ?   ?   B . n 
C 2 52  GLY 52  -2  ?   ?   ?   B . n 
C 2 53  THR 53  -1  ?   ?   ?   B . n 
C 2 54  GLY 54  0   ?   ?   ?   B . n 
C 2 55  GLN 55  1   ?   ?   ?   B . n 
C 2 56  SER 56  2   ?   ?   ?   B . n 
C 2 57  VAL 57  3   ?   ?   ?   B . n 
C 2 58  ASN 58  4   ?   ?   ?   B . n 
C 2 59  ASP 59  5   ?   ?   ?   B . n 
C 2 60  PRO 60  6   ?   ?   ?   B . n 
C 2 61  GLY 61  7   ?   ?   ?   B . n 
C 2 62  ASN 62  8   8   ASN ASN B . n 
C 2 63  MET 63  9   9   MET MET B . n 
C 2 64  SER 64  10  10  SER SER B . n 
C 2 65  PHE 65  11  11  PHE PHE B . n 
C 2 66  VAL 66  12  12  VAL VAL B . n 
C 2 67  LYS 67  13  13  LYS LYS B . n 
C 2 68  GLU 68  14  14  GLU GLU B . n 
C 2 69  THR 69  15  15  THR THR B . n 
C 2 70  VAL 70  16  16  VAL VAL B . n 
C 2 71  ASP 71  17  17  ASP ASP B . n 
C 2 72  LYS 72  18  18  LYS LYS B . n 
C 2 73  LEU 73  19  19  LEU LEU B . n 
C 2 74  LEU 74  20  20  LEU LEU B . n 
C 2 75  LYS 75  21  21  LYS LYS B . n 
C 2 76  GLY 76  22  22  GLY GLY B . n 
C 2 77  TYR 77  23  23  TYR TYR B . n 
C 2 78  ASP 78  24  24  ASP ASP B . n 
C 2 79  ILE 79  25  25  ILE ILE B . n 
C 2 80  ARG 80  26  26  ARG ARG B . n 
C 2 81  LEU 81  27  27  LEU LEU B . n 
C 2 82  ARG 82  28  28  ARG ARG B . n 
C 2 83  PRO 83  29  29  PRO PRO B . n 
C 2 84  ASP 84  30  30  ASP ASP B . n 
C 2 85  PHE 85  31  31  PHE PHE B . n 
C 2 86  GLY 86  32  32  GLY GLY B . n 
C 2 87  GLY 87  33  33  GLY GLY B . n 
C 2 88  PRO 88  34  34  PRO PRO B . n 
C 2 89  PRO 89  35  35  PRO PRO B . n 
C 2 90  VAL 90  36  36  VAL VAL B . n 
C 2 91  CYS 91  37  37  CYS CYS B . n 
C 2 92  VAL 92  38  38  VAL VAL B . n 
C 2 93  GLY 93  39  39  GLY GLY B . n 
C 2 94  MET 94  40  40  MET MET B . n 
C 2 95  ASN 95  41  41  ASN ASN B . n 
C 2 96  ILE 96  42  42  ILE ILE B . n 
C 2 97  ASP 97  43  43  ASP ASP B . n 
C 2 98  ILE 98  44  44  ILE ILE B . n 
C 2 99  ALA 99  45  45  ALA ALA B . n 
C 2 100 SER 100 46  46  SER SER B . n 
C 2 101 ILE 101 47  47  ILE ILE B . n 
C 2 102 ASP 102 48  48  ASP ASP B . n 
C 2 103 MET 103 49  49  MET MET B . n 
C 2 104 VAL 104 50  50  VAL VAL B . n 
C 2 105 SER 105 51  51  SER SER B . n 
C 2 106 GLU 106 52  52  GLU GLU B . n 
C 2 107 VAL 107 53  53  VAL VAL B . n 
C 2 108 ASN 108 54  54  ASN ASN B . n 
C 2 109 MET 109 55  55  MET MET B . n 
C 2 110 ASP 110 56  56  ASP ASP B . n 
C 2 111 TYR 111 57  57  TYR TYR B . n 
C 2 112 THR 112 58  58  THR THR B . n 
C 2 113 LEU 113 59  59  LEU LEU B . n 
C 2 114 THR 114 60  60  THR THR B . n 
C 2 115 MET 115 61  61  MET MET B . n 
C 2 116 TYR 116 62  62  TYR TYR B . n 
C 2 117 PHE 117 63  63  PHE PHE B . n 
C 2 118 GLN 118 64  64  GLN GLN B . n 
C 2 119 GLN 119 65  65  GLN GLN B . n 
C 2 120 TYR 120 66  66  TYR TYR B . n 
C 2 121 TRP 121 67  67  TRP TRP B . n 
C 2 122 ARG 122 68  68  ARG ARG B . n 
C 2 123 ASP 123 69  69  ASP ASP B . n 
C 2 124 LYS 124 70  70  LYS LYS B . n 
C 2 125 ARG 125 71  71  ARG ARG B . n 
C 2 126 LEU 126 72  72  LEU LEU B . n 
C 2 127 ALA 127 73  73  ALA ALA B . n 
C 2 128 TYR 128 74  74  TYR TYR B . n 
C 2 129 SER 129 75  75  SER SER B . n 
C 2 130 GLY 130 76  76  GLY GLY B . n 
C 2 131 ILE 131 77  77  ILE ILE B . n 
C 2 132 PRO 132 78  78  PRO PRO B . n 
C 2 133 LEU 133 79  79  LEU LEU B . n 
C 2 134 ASN 134 80  80  ASN ASN B . n 
C 2 135 LEU 135 81  81  LEU LEU B . n 
C 2 136 THR 136 82  82  THR THR B . n 
C 2 137 LEU 137 83  83  LEU LEU B . n 
C 2 138 ASP 138 84  84  ASP ASP B . n 
C 2 139 ASN 139 85  85  ASN ASN B . n 
C 2 140 ARG 140 86  86  ARG ARG B . n 
C 2 141 VAL 141 87  87  VAL VAL B . n 
C 2 142 ALA 142 88  88  ALA ALA B . n 
C 2 143 ASP 143 89  89  ASP ASP B . n 
C 2 144 GLN 144 90  90  GLN GLN B . n 
C 2 145 LEU 145 91  91  LEU LEU B . n 
C 2 146 TRP 146 92  92  TRP TRP B . n 
C 2 147 VAL 147 93  93  VAL VAL B . n 
C 2 148 PRO 148 94  94  PRO PRO B . n 
C 2 149 ASP 149 95  95  ASP ASP B . n 
C 2 150 THR 150 96  96  THR THR B . n 
C 2 151 TYR 151 97  97  TYR TYR B . n 
C 2 152 PHE 152 98  98  PHE PHE B . n 
C 2 153 LEU 153 99  99  LEU LEU B . n 
C 2 154 ASN 154 100 100 ASN ASN B . n 
C 2 155 ASP 155 101 101 ASP ASP B . n 
C 2 156 LYS 156 102 102 LYS LYS B . n 
C 2 157 LYS 157 103 103 LYS LYS B . n 
C 2 158 SER 158 104 104 SER SER B . n 
C 2 159 PHE 159 105 105 PHE PHE B . n 
C 2 160 VAL 160 106 106 VAL VAL B . n 
C 2 161 HIS 161 107 107 HIS HIS B . n 
C 2 162 GLY 162 108 108 GLY GLY B . n 
C 2 163 VAL 163 109 109 VAL VAL B . n 
C 2 164 THR 164 110 110 THR THR B . n 
C 2 165 VAL 165 111 111 VAL VAL B . n 
C 2 166 LYS 166 112 112 LYS LYS B . n 
C 2 167 ASN 167 113 113 ASN ASN B . n 
C 2 168 ARG 168 114 114 ARG ARG B . n 
C 2 169 MET 169 115 115 MET MET B . n 
C 2 170 ILE 170 116 116 ILE ILE B . n 
C 2 171 ARG 171 117 117 ARG ARG B . n 
C 2 172 LEU 172 118 118 LEU LEU B . n 
C 2 173 HIS 173 119 119 HIS HIS B . n 
C 2 174 PRO 174 120 120 PRO PRO B . n 
C 2 175 ASP 175 121 121 ASP ASP B . n 
C 2 176 GLY 176 122 122 GLY GLY B . n 
C 2 177 THR 177 123 123 THR THR B . n 
C 2 178 VAL 178 124 124 VAL VAL B . n 
C 2 179 LEU 179 125 125 LEU LEU B . n 
C 2 180 TYR 180 126 126 TYR TYR B . n 
C 2 181 GLY 181 127 127 GLY GLY B . n 
C 2 182 LEU 182 128 128 LEU LEU B . n 
C 2 183 ARG 183 129 129 ARG ARG B . n 
C 2 184 ILE 184 130 130 ILE ILE B . n 
C 2 185 THR 185 131 131 THR THR B . n 
C 2 186 THR 186 132 132 THR THR B . n 
C 2 187 THR 187 133 133 THR THR B . n 
C 2 188 ALA 188 134 134 ALA ALA B . n 
C 2 189 ALA 189 135 135 ALA ALA B . n 
C 2 190 CYS 190 136 136 CYS CYS B . n 
C 2 191 MET 191 137 137 MET MET B . n 
C 2 192 MET 192 138 138 MET MET B . n 
C 2 193 ASP 193 139 139 ASP ASP B . n 
C 2 194 LEU 194 140 140 LEU LEU B . n 
C 2 195 ARG 195 141 141 ARG ARG B . n 
C 2 196 ARG 196 142 142 ARG ARG B . n 
C 2 197 TYR 197 143 143 TYR TYR B . n 
C 2 198 PRO 198 144 144 PRO PRO B . n 
C 2 199 LEU 199 145 145 LEU LEU B . n 
C 2 200 ASP 200 146 146 ASP ASP B . n 
C 2 201 GLU 201 147 147 GLU GLU B . n 
C 2 202 GLN 202 148 148 GLN GLN B . n 
C 2 203 ASN 203 149 149 ASN ASN B . n 
C 2 204 CYS 204 150 150 CYS CYS B . n 
C 2 205 THR 205 151 151 THR THR B . n 
C 2 206 LEU 206 152 152 LEU LEU B . n 
C 2 207 GLU 207 153 153 GLU GLU B . n 
C 2 208 ILE 208 154 154 ILE ILE B . n 
C 2 209 GLU 209 155 155 GLU GLU B . n 
C 2 210 SER 210 156 156 SER SER B . n 
C 2 211 TYR 211 157 157 TYR TYR B . n 
C 2 212 GLY 212 158 158 GLY GLY B . n 
C 2 213 TYR 213 159 159 TYR TYR B . n 
C 2 214 THR 214 160 160 THR THR B . n 
C 2 215 THR 215 161 161 THR THR B . n 
C 2 216 ASP 216 162 162 ASP ASP B . n 
C 2 217 ASP 217 163 163 ASP ASP B . n 
C 2 218 ILE 218 164 164 ILE ILE B . n 
C 2 219 GLU 219 165 165 GLU GLU B . n 
C 2 220 PHE 220 166 166 PHE PHE B . n 
C 2 221 TYR 221 167 167 TYR TYR B . n 
C 2 222 TRP 222 168 168 TRP TRP B . n 
C 2 223 ARG 223 169 169 ARG ARG B . n 
C 2 224 GLY 224 170 170 GLY GLY B . n 
C 2 225 GLY 225 171 171 GLY GLY B . n 
C 2 226 ASP 226 172 172 ASP ASP B . n 
C 2 227 LYS 227 173 173 LYS LYS B . n 
C 2 228 ALA 228 174 174 ALA ALA B . n 
C 2 229 VAL 229 175 175 VAL VAL B . n 
C 2 230 THR 230 176 176 THR THR B . n 
C 2 231 GLY 231 177 177 GLY GLY B . n 
C 2 232 VAL 232 178 178 VAL VAL B . n 
C 2 233 GLU 233 179 179 GLU GLU B . n 
C 2 234 ARG 234 180 180 ARG ARG B . n 
C 2 235 ILE 235 181 181 ILE ILE B . n 
C 2 236 GLU 236 182 182 GLU GLU B . n 
C 2 237 LEU 237 183 183 LEU LEU B . n 
C 2 238 PRO 238 184 184 PRO PRO B . n 
C 2 239 GLN 239 185 185 GLN GLN B . n 
C 2 240 PHE 240 186 186 PHE PHE B . n 
C 2 241 SER 241 187 187 SER SER B . n 
C 2 242 ILE 242 188 188 ILE ILE B . n 
C 2 243 VAL 243 189 189 VAL VAL B . n 
C 2 244 GLU 244 190 190 GLU GLU B . n 
C 2 245 HIS 245 191 191 HIS HIS B . n 
C 2 246 ARG 246 192 192 ARG ARG B . n 
C 2 247 LEU 247 193 193 LEU LEU B . n 
C 2 248 VAL 248 194 194 VAL VAL B . n 
C 2 249 SER 249 195 195 SER SER B . n 
C 2 250 ARG 250 196 196 ARG ARG B . n 
C 2 251 ASN 251 197 197 ASN ASN B . n 
C 2 252 VAL 252 198 198 VAL VAL B . n 
C 2 253 VAL 253 199 199 VAL VAL B . n 
C 2 254 PHE 254 200 200 PHE PHE B . n 
C 2 255 ALA 255 201 201 ALA ALA B . n 
C 2 256 THR 256 202 202 THR THR B . n 
C 2 257 GLY 257 203 203 GLY GLY B . n 
C 2 258 ALA 258 204 204 ALA ALA B . n 
C 2 259 TYR 259 205 205 TYR TYR B . n 
C 2 260 PRO 260 206 206 PRO PRO B . n 
C 2 261 ARG 261 207 207 ARG ARG B . n 
C 2 262 LEU 262 208 208 LEU LEU B . n 
C 2 263 SER 263 209 209 SER SER B . n 
C 2 264 LEU 264 210 210 LEU LEU B . n 
C 2 265 SER 265 211 211 SER SER B . n 
C 2 266 PHE 266 212 212 PHE PHE B . n 
C 2 267 ARG 267 213 213 ARG ARG B . n 
C 2 268 LEU 268 214 214 LEU LEU B . n 
C 2 269 LYS 269 215 215 LYS LYS B . n 
C 2 270 ARG 270 216 216 ARG ARG B . n 
C 2 271 ASN 271 217 217 ASN ASN B . n 
C 2 272 ILE 272 218 218 ILE ILE B . n 
C 2 273 GLY 273 219 219 GLY GLY B . n 
C 2 274 TYR 274 220 220 TYR TYR B . n 
C 2 275 PHE 275 221 221 PHE PHE B . n 
C 2 276 ILE 276 222 222 ILE ILE B . n 
C 2 277 LEU 277 223 223 LEU LEU B . n 
C 2 278 GLN 278 224 224 GLN GLN B . n 
C 2 279 THR 279 225 225 THR THR B . n 
C 2 280 TYR 280 226 226 TYR TYR B . n 
C 2 281 MET 281 227 227 MET MET B . n 
C 2 282 PRO 282 228 228 PRO PRO B . n 
C 2 283 SER 283 229 229 SER SER B . n 
C 2 284 ILE 284 230 230 ILE ILE B . n 
C 2 285 LEU 285 231 231 LEU LEU B . n 
C 2 286 ILE 286 232 232 ILE ILE B . n 
C 2 287 THR 287 233 233 THR THR B . n 
C 2 288 ILE 288 234 234 ILE ILE B . n 
C 2 289 LEU 289 235 235 LEU LEU B . n 
C 2 290 SER 290 236 236 SER SER B . n 
C 2 291 TRP 291 237 237 TRP TRP B . n 
C 2 292 VAL 292 238 238 VAL VAL B . n 
C 2 293 SER 293 239 239 SER SER B . n 
C 2 294 PHE 294 240 240 PHE PHE B . n 
C 2 295 TRP 295 241 241 TRP TRP B . n 
C 2 296 ILE 296 242 242 ILE ILE B . n 
C 2 297 ASN 297 243 243 ASN ASN B . n 
C 2 298 TYR 298 244 244 TYR TYR B . n 
C 2 299 ASP 299 245 245 ASP ASP B . n 
C 2 300 ALA 300 246 246 ALA ALA B . n 
C 2 301 SER 301 247 247 SER SER B . n 
C 2 302 ALA 302 248 248 ALA ALA B . n 
C 2 303 ALA 303 249 249 ALA ALA B . n 
C 2 304 ARG 304 250 250 ARG ARG B . n 
C 2 305 VAL 305 251 251 VAL VAL B . n 
C 2 306 ALA 306 252 252 ALA ALA B . n 
C 2 307 LEU 307 253 253 LEU LEU B . n 
C 2 308 GLY 308 254 254 GLY GLY B . n 
C 2 309 ILE 309 255 255 ILE ILE B . n 
C 2 310 THR 310 256 256 THR THR B . n 
C 2 311 THR 311 257 257 THR THR B . n 
C 2 312 VAL 312 258 258 VAL VAL B . n 
C 2 313 LEU 313 259 259 LEU LEU B . n 
C 2 314 THR 314 260 260 THR THR B . n 
C 2 315 MET 315 261 261 MET MET B . n 
C 2 316 THR 316 262 262 THR THR B . n 
C 2 317 THR 317 263 263 THR THR B . n 
C 2 318 ILE 318 264 264 ILE ILE B . n 
C 2 319 ASN 319 265 265 ASN ASN B . n 
C 2 320 THR 320 266 266 THR THR B . n 
C 2 321 HIS 321 267 267 HIS HIS B . n 
C 2 322 LEU 322 268 268 LEU LEU B . n 
C 2 323 ARG 323 269 269 ARG ARG B . n 
C 2 324 GLU 324 270 270 GLU GLU B . n 
C 2 325 THR 325 271 271 THR THR B . n 
C 2 326 LEU 326 272 272 LEU LEU B . n 
C 2 327 PRO 327 273 273 PRO PRO B . n 
C 2 328 LYS 328 274 274 LYS LYS B . n 
C 2 329 ILE 329 275 275 ILE ILE B . n 
C 2 330 PRO 330 276 276 PRO PRO B . n 
C 2 331 TYR 331 277 277 TYR TYR B . n 
C 2 332 VAL 332 278 278 VAL VAL B . n 
C 2 333 LYS 333 279 279 LYS LYS B . n 
C 2 334 ALA 334 280 280 ALA ALA B . n 
C 2 335 ILE 335 281 281 ILE ILE B . n 
C 2 336 ASP 336 282 282 ASP ASP B . n 
C 2 337 MET 337 283 283 MET MET B . n 
C 2 338 TYR 338 284 284 TYR TYR B . n 
C 2 339 LEU 339 285 285 LEU LEU B . n 
C 2 340 MET 340 286 286 MET MET B . n 
C 2 341 GLY 341 287 287 GLY GLY B . n 
C 2 342 CYS 342 288 288 CYS CYS B . n 
C 2 343 PHE 343 289 289 PHE PHE B . n 
C 2 344 VAL 344 290 290 VAL VAL B . n 
C 2 345 PHE 345 291 291 PHE PHE B . n 
C 2 346 VAL 346 292 292 VAL VAL B . n 
C 2 347 PHE 347 293 293 PHE PHE B . n 
C 2 348 LEU 348 294 294 LEU LEU B . n 
C 2 349 ALA 349 295 295 ALA ALA B . n 
C 2 350 LEU 350 296 296 LEU LEU B . n 
C 2 351 LEU 351 297 297 LEU LEU B . n 
C 2 352 GLU 352 298 298 GLU GLU B . n 
C 2 353 TYR 353 299 299 TYR TYR B . n 
C 2 354 ALA 354 300 300 ALA ALA B . n 
C 2 355 PHE 355 301 301 PHE PHE B . n 
C 2 356 VAL 356 302 302 VAL VAL B . n 
C 2 357 ASN 357 303 303 ASN ASN B . n 
C 2 358 TYR 358 304 304 TYR TYR B . n 
C 2 359 ILE 359 305 305 ILE ILE B . n 
C 2 360 PHE 360 306 306 PHE PHE B . n 
C 2 361 PHE 361 307 307 PHE PHE B . n 
C 2 362 SER 362 308 308 SER SER B . n 
C 2 363 GLN 363 309 309 GLN GLN B . n 
C 2 364 PRO 364 310 310 PRO PRO B . n 
C 2 365 ALA 365 311 311 ALA ALA B . n 
C 2 366 ARG 366 312 312 ARG ARG B . n 
C 2 367 ALA 367 313 313 ALA ALA B . n 
C 2 368 ALA 368 314 314 ALA ALA B . n 
C 2 369 ALA 369 422 422 ALA ALA B . n 
C 2 370 ILE 370 423 423 ILE ILE B . n 
C 2 371 ASP 371 424 424 ASP ASP B . n 
C 2 372 ARG 372 425 425 ARG ARG B . n 
C 2 373 TRP 373 426 426 TRP TRP B . n 
C 2 374 SER 374 427 427 SER SER B . n 
C 2 375 ARG 375 428 428 ARG ARG B . n 
C 2 376 ILE 376 429 429 ILE ILE B . n 
C 2 377 VAL 377 430 430 VAL VAL B . n 
C 2 378 PHE 378 431 431 PHE PHE B . n 
C 2 379 PRO 379 432 432 PRO PRO B . n 
C 2 380 PHE 380 433 433 PHE PHE B . n 
C 2 381 THR 381 434 434 THR THR B . n 
C 2 382 PHE 382 435 435 PHE PHE B . n 
C 2 383 SER 383 436 436 SER SER B . n 
C 2 384 LEU 384 437 437 LEU LEU B . n 
C 2 385 PHE 385 438 438 PHE PHE B . n 
C 2 386 ASN 386 439 439 ASN ASN B . n 
C 2 387 LEU 387 440 440 LEU LEU B . n 
C 2 388 VAL 388 441 441 VAL VAL B . n 
C 2 389 TYR 389 442 442 TYR TYR B . n 
C 2 390 TRP 390 443 443 TRP TRP B . n 
C 2 391 LEU 391 444 444 LEU LEU B . n 
C 2 392 TYR 392 445 445 TYR TYR B . n 
C 2 393 TYR 393 446 446 TYR TYR B . n 
C 2 394 VAL 394 447 447 VAL VAL B . n 
C 2 395 ASN 395 448 ?   ?   ?   B . n 
D 1 1   MET 1   -52 ?   ?   ?   A . n 
D 1 2   ASP 2   -51 ?   ?   ?   A . n 
D 1 3   GLU 3   -50 ?   ?   ?   A . n 
D 1 4   LYS 4   -49 ?   ?   ?   A . n 
D 1 5   THR 5   -48 ?   ?   ?   A . n 
D 1 6   THR 6   -47 ?   ?   ?   A . n 
D 1 7   GLY 7   -46 ?   ?   ?   A . n 
D 1 8   TRP 8   -45 ?   ?   ?   A . n 
D 1 9   ARG 9   -44 ?   ?   ?   A . n 
D 1 10  GLY 10  -43 ?   ?   ?   A . n 
D 1 11  GLY 11  -42 ?   ?   ?   A . n 
D 1 12  HIS 12  -41 ?   ?   ?   A . n 
D 1 13  VAL 13  -40 ?   ?   ?   A . n 
D 1 14  VAL 14  -39 ?   ?   ?   A . n 
D 1 15  GLU 15  -38 ?   ?   ?   A . n 
D 1 16  GLY 16  -37 ?   ?   ?   A . n 
D 1 17  LEU 17  -36 ?   ?   ?   A . n 
D 1 18  ALA 18  -35 ?   ?   ?   A . n 
D 1 19  GLY 19  -34 ?   ?   ?   A . n 
D 1 20  GLU 20  -33 ?   ?   ?   A . n 
D 1 21  LEU 21  -32 ?   ?   ?   A . n 
D 1 22  GLU 22  -31 ?   ?   ?   A . n 
D 1 23  GLN 23  -30 ?   ?   ?   A . n 
D 1 24  LEU 24  -29 ?   ?   ?   A . n 
D 1 25  ARG 25  -28 ?   ?   ?   A . n 
D 1 26  ALA 26  -27 ?   ?   ?   A . n 
D 1 27  ARG 27  -26 ?   ?   ?   A . n 
D 1 28  LEU 28  -25 ?   ?   ?   A . n 
D 1 29  GLU 29  -24 ?   ?   ?   A . n 
D 1 30  HIS 30  -23 ?   ?   ?   A . n 
D 1 31  HIS 31  -22 ?   ?   ?   A . n 
D 1 32  PRO 32  -21 ?   ?   ?   A . n 
D 1 33  GLN 33  -20 ?   ?   ?   A . n 
D 1 34  GLY 34  -19 ?   ?   ?   A . n 
D 1 35  GLN 35  -18 ?   ?   ?   A . n 
D 1 36  ARG 36  -17 ?   ?   ?   A . n 
D 1 37  GLU 37  -16 ?   ?   ?   A . n 
D 1 38  PRO 38  -15 ?   ?   ?   A . n 
D 1 39  ASP 39  -14 ?   ?   ?   A . n 
D 1 40  TYR 40  -13 ?   ?   ?   A . n 
D 1 41  ASP 41  -12 ?   ?   ?   A . n 
D 1 42  ILE 42  -11 ?   ?   ?   A . n 
D 1 43  PRO 43  -10 ?   ?   ?   A . n 
D 1 44  THR 44  -9  ?   ?   ?   A . n 
D 1 45  THR 45  -8  ?   ?   ?   A . n 
D 1 46  GLU 46  -7  ?   ?   ?   A . n 
D 1 47  ASN 47  -6  ?   ?   ?   A . n 
D 1 48  LEU 48  -5  ?   ?   ?   A . n 
D 1 49  TYR 49  -4  ?   ?   ?   A . n 
D 1 50  PHE 50  -3  ?   ?   ?   A . n 
D 1 51  GLN 51  -2  ?   ?   ?   A . n 
D 1 52  GLY 52  -1  ?   ?   ?   A . n 
D 1 53  THR 53  0   ?   ?   ?   A . n 
D 1 54  GLY 54  1   ?   ?   ?   A . n 
D 1 55  GLN 55  2   ?   ?   ?   A . n 
D 1 56  PRO 56  3   ?   ?   ?   A . n 
D 1 57  SER 57  4   ?   ?   ?   A . n 
D 1 58  GLN 58  5   ?   ?   ?   A . n 
D 1 59  ASP 59  6   ?   ?   ?   A . n 
D 1 60  GLU 60  7   ?   ?   ?   A . n 
D 1 61  LEU 61  8   ?   ?   ?   A . n 
D 1 62  LYS 62  9   ?   ?   ?   A . n 
D 1 63  ASP 63  10  ?   ?   ?   A . n 
D 1 64  ASN 64  11  ?   ?   ?   A . n 
D 1 65  THR 65  12  12  THR THR A . n 
D 1 66  THR 66  13  13  THR THR A . n 
D 1 67  VAL 67  14  14  VAL VAL A . n 
D 1 68  PHE 68  15  15  PHE PHE A . n 
D 1 69  THR 69  16  16  THR THR A . n 
D 1 70  ARG 70  17  17  ARG ARG A . n 
D 1 71  ILE 71  18  18  ILE ILE A . n 
D 1 72  LEU 72  19  19  LEU LEU A . n 
D 1 73  ASP 73  20  20  ASP ASP A . n 
D 1 74  ARG 74  21  21  ARG ARG A . n 
D 1 75  LEU 75  22  22  LEU LEU A . n 
D 1 76  LEU 76  23  23  LEU LEU A . n 
D 1 77  ASP 77  24  24  ASP ASP A . n 
D 1 78  GLY 78  25  25  GLY GLY A . n 
D 1 79  TYR 79  26  26  TYR TYR A . n 
D 1 80  ASP 80  27  27  ASP ASP A . n 
D 1 81  ASN 81  28  28  ASN ASN A . n 
D 1 82  ARG 82  29  29  ARG ARG A . n 
D 1 83  LEU 83  30  30  LEU LEU A . n 
D 1 84  ARG 84  31  31  ARG ARG A . n 
D 1 85  PRO 85  32  32  PRO PRO A . n 
D 1 86  GLY 86  33  33  GLY GLY A . n 
D 1 87  LEU 87  34  34  LEU LEU A . n 
D 1 88  GLY 88  35  35  GLY GLY A . n 
D 1 89  GLU 89  36  36  GLU GLU A . n 
D 1 90  ARG 90  37  37  ARG ARG A . n 
D 1 91  VAL 91  38  38  VAL VAL A . n 
D 1 92  THR 92  39  39  THR THR A . n 
D 1 93  GLU 93  40  40  GLU GLU A . n 
D 1 94  VAL 94  41  41  VAL VAL A . n 
D 1 95  LYS 95  42  42  LYS LYS A . n 
D 1 96  THR 96  43  43  THR THR A . n 
D 1 97  ASP 97  44  44  ASP ASP A . n 
D 1 98  ILE 98  45  45  ILE ILE A . n 
D 1 99  PHE 99  46  46  PHE PHE A . n 
D 1 100 VAL 100 47  47  VAL VAL A . n 
D 1 101 THR 101 48  48  THR THR A . n 
D 1 102 SER 102 49  49  SER SER A . n 
D 1 103 PHE 103 50  50  PHE PHE A . n 
D 1 104 GLY 104 51  51  GLY GLY A . n 
D 1 105 PRO 105 52  52  PRO PRO A . n 
D 1 106 VAL 106 53  53  VAL VAL A . n 
D 1 107 SER 107 54  54  SER SER A . n 
D 1 108 ASP 108 55  55  ASP ASP A . n 
D 1 109 HIS 109 56  56  HIS HIS A . n 
D 1 110 ASP 110 57  57  ASP ASP A . n 
D 1 111 MET 111 58  58  MET MET A . n 
D 1 112 GLU 112 59  59  GLU GLU A . n 
D 1 113 TYR 113 60  60  TYR TYR A . n 
D 1 114 THR 114 61  61  THR THR A . n 
D 1 115 ILE 115 62  62  ILE ILE A . n 
D 1 116 ASP 116 63  63  ASP ASP A . n 
D 1 117 VAL 117 64  64  VAL VAL A . n 
D 1 118 PHE 118 65  65  PHE PHE A . n 
D 1 119 PHE 119 66  66  PHE PHE A . n 
D 1 120 ARG 120 67  67  ARG ARG A . n 
D 1 121 GLN 121 68  68  GLN GLN A . n 
D 1 122 SER 122 69  69  SER SER A . n 
D 1 123 TRP 123 70  70  TRP TRP A . n 
D 1 124 LYS 124 71  71  LYS LYS A . n 
D 1 125 ASP 125 72  72  ASP ASP A . n 
D 1 126 GLU 126 73  73  GLU GLU A . n 
D 1 127 ARG 127 74  74  ARG ARG A . n 
D 1 128 LEU 128 75  75  LEU LEU A . n 
D 1 129 LYS 129 76  76  LYS LYS A . n 
D 1 130 PHE 130 77  77  PHE PHE A . n 
D 1 131 LYS 131 78  78  LYS LYS A . n 
D 1 132 GLY 132 79  79  GLY GLY A . n 
D 1 133 PRO 133 80  80  PRO PRO A . n 
D 1 134 MET 134 81  81  MET MET A . n 
D 1 135 THR 135 82  82  THR THR A . n 
D 1 136 VAL 136 83  83  VAL VAL A . n 
D 1 137 LEU 137 84  84  LEU LEU A . n 
D 1 138 ARG 138 85  85  ARG ARG A . n 
D 1 139 LEU 139 86  86  LEU LEU A . n 
D 1 140 ASN 140 87  87  ASN ASN A . n 
D 1 141 ASN 141 88  88  ASN ASN A . n 
D 1 142 LEU 142 89  89  LEU LEU A . n 
D 1 143 MET 143 90  90  MET MET A . n 
D 1 144 ALA 144 91  91  ALA ALA A . n 
D 1 145 SER 145 92  92  SER SER A . n 
D 1 146 LYS 146 93  93  LYS LYS A . n 
D 1 147 ILE 147 94  94  ILE ILE A . n 
D 1 148 TRP 148 95  95  TRP TRP A . n 
D 1 149 THR 149 96  96  THR THR A . n 
D 1 150 PRO 150 97  97  PRO PRO A . n 
D 1 151 ASP 151 98  98  ASP ASP A . n 
D 1 152 THR 152 99  99  THR THR A . n 
D 1 153 PHE 153 100 100 PHE PHE A . n 
D 1 154 PHE 154 101 101 PHE PHE A . n 
D 1 155 HIS 155 102 102 HIS HIS A . n 
D 1 156 ASN 156 103 103 ASN ASN A . n 
D 1 157 GLY 157 104 104 GLY GLY A . n 
D 1 158 LYS 158 105 105 LYS LYS A . n 
D 1 159 LYS 159 106 106 LYS LYS A . n 
D 1 160 SER 160 107 107 SER SER A . n 
D 1 161 VAL 161 108 108 VAL VAL A . n 
D 1 162 ALA 162 109 109 ALA ALA A . n 
D 1 163 HIS 163 110 110 HIS HIS A . n 
D 1 164 ASN 164 111 111 ASN ASN A . n 
D 1 165 MET 165 112 112 MET MET A . n 
D 1 166 THR 166 113 113 THR THR A . n 
D 1 167 MET 167 114 114 MET MET A . n 
D 1 168 PRO 168 115 115 PRO PRO A . n 
D 1 169 ASN 169 116 116 ASN ASN A . n 
D 1 170 LYS 170 117 117 LYS LYS A . n 
D 1 171 LEU 171 118 118 LEU LEU A . n 
D 1 172 LEU 172 119 119 LEU LEU A . n 
D 1 173 ARG 173 120 120 ARG ARG A . n 
D 1 174 ILE 174 121 121 ILE ILE A . n 
D 1 175 THR 175 122 122 THR THR A . n 
D 1 176 GLU 176 123 123 GLU GLU A . n 
D 1 177 ASP 177 124 124 ASP ASP A . n 
D 1 178 GLY 178 125 125 GLY GLY A . n 
D 1 179 THR 179 126 126 THR THR A . n 
D 1 180 LEU 180 127 127 LEU LEU A . n 
D 1 181 LEU 181 128 128 LEU LEU A . n 
D 1 182 TYR 182 129 129 TYR TYR A . n 
D 1 183 THR 183 130 130 THR THR A . n 
D 1 184 MET 184 131 131 MET MET A . n 
D 1 185 ARG 185 132 132 ARG ARG A . n 
D 1 186 LEU 186 133 133 LEU LEU A . n 
D 1 187 THR 187 134 134 THR THR A . n 
D 1 188 VAL 188 135 135 VAL VAL A . n 
D 1 189 ARG 189 136 136 ARG ARG A . n 
D 1 190 ALA 190 137 137 ALA ALA A . n 
D 1 191 GLU 191 138 138 GLU GLU A . n 
D 1 192 CYS 192 139 139 CYS CYS A . n 
D 1 193 PRO 193 140 140 PRO PRO A . n 
D 1 194 MET 194 141 141 MET MET A . n 
D 1 195 HIS 195 142 142 HIS HIS A . n 
D 1 196 LEU 196 143 143 LEU LEU A . n 
D 1 197 GLU 197 144 144 GLU GLU A . n 
D 1 198 ASP 198 145 145 ASP ASP A . n 
D 1 199 PHE 199 146 146 PHE PHE A . n 
D 1 200 PRO 200 147 147 PRO PRO A . n 
D 1 201 MET 201 148 148 MET MET A . n 
D 1 202 ASP 202 149 149 ASP ASP A . n 
D 1 203 ALA 203 150 150 ALA ALA A . n 
D 1 204 HIS 204 151 151 HIS HIS A . n 
D 1 205 ALA 205 152 152 ALA ALA A . n 
D 1 206 CYS 206 153 153 CYS CYS A . n 
D 1 207 PRO 207 154 154 PRO PRO A . n 
D 1 208 LEU 208 155 155 LEU LEU A . n 
D 1 209 LYS 209 156 156 LYS LYS A . n 
D 1 210 PHE 210 157 157 PHE PHE A . n 
D 1 211 GLY 211 158 158 GLY GLY A . n 
D 1 212 SER 212 159 159 SER SER A . n 
D 1 213 TYR 213 160 160 TYR TYR A . n 
D 1 214 ALA 214 161 161 ALA ALA A . n 
D 1 215 TYR 215 162 162 TYR TYR A . n 
D 1 216 THR 216 163 163 THR THR A . n 
D 1 217 ARG 217 164 164 ARG ARG A . n 
D 1 218 ALA 218 165 165 ALA ALA A . n 
D 1 219 GLU 219 166 166 GLU GLU A . n 
D 1 220 VAL 220 167 167 VAL VAL A . n 
D 1 221 VAL 221 168 168 VAL VAL A . n 
D 1 222 TYR 222 169 169 TYR TYR A . n 
D 1 223 GLU 223 170 170 GLU GLU A . n 
D 1 224 TRP 224 171 171 TRP TRP A . n 
D 1 225 THR 225 172 172 THR THR A . n 
D 1 226 ARG 226 173 173 ARG ARG A . n 
D 1 227 GLU 227 174 174 GLU GLU A . n 
D 1 228 PRO 228 175 175 PRO PRO A . n 
D 1 229 ALA 229 176 176 ALA ALA A . n 
D 1 230 ARG 230 177 177 ARG ARG A . n 
D 1 231 SER 231 178 178 SER SER A . n 
D 1 232 VAL 232 179 179 VAL VAL A . n 
D 1 233 VAL 233 180 180 VAL VAL A . n 
D 1 234 VAL 234 181 181 VAL VAL A . n 
D 1 235 ALA 235 182 182 ALA ALA A . n 
D 1 236 GLU 236 183 183 GLU GLU A . n 
D 1 237 ASP 237 184 184 ASP ASP A . n 
D 1 238 GLY 238 185 185 GLY GLY A . n 
D 1 239 SER 239 186 186 SER SER A . n 
D 1 240 ARG 240 187 187 ARG ARG A . n 
D 1 241 LEU 241 188 188 LEU LEU A . n 
D 1 242 ASN 242 189 189 ASN ASN A . n 
D 1 243 GLN 243 190 190 GLN GLN A . n 
D 1 244 TYR 244 191 191 TYR TYR A . n 
D 1 245 ASP 245 192 192 ASP ASP A . n 
D 1 246 LEU 246 193 193 LEU LEU A . n 
D 1 247 LEU 247 194 194 LEU LEU A . n 
D 1 248 GLY 248 195 195 GLY GLY A . n 
D 1 249 GLN 249 196 196 GLN GLN A . n 
D 1 250 THR 250 197 197 THR THR A . n 
D 1 251 VAL 251 198 198 VAL VAL A . n 
D 1 252 ASP 252 199 199 ASP ASP A . n 
D 1 253 SER 253 200 200 SER SER A . n 
D 1 254 GLY 254 201 201 GLY GLY A . n 
D 1 255 ILE 255 202 202 ILE ILE A . n 
D 1 256 VAL 256 203 203 VAL VAL A . n 
D 1 257 GLN 257 204 204 GLN GLN A . n 
D 1 258 SER 258 205 205 SER SER A . n 
D 1 259 SER 259 206 206 SER SER A . n 
D 1 260 THR 260 207 207 THR THR A . n 
D 1 261 GLY 261 208 208 GLY GLY A . n 
D 1 262 GLU 262 209 209 GLU GLU A . n 
D 1 263 TYR 263 210 210 TYR TYR A . n 
D 1 264 VAL 264 211 211 VAL VAL A . n 
D 1 265 VAL 265 212 212 VAL VAL A . n 
D 1 266 MET 266 213 213 MET MET A . n 
D 1 267 THR 267 214 214 THR THR A . n 
D 1 268 THR 268 215 215 THR THR A . n 
D 1 269 HIS 269 216 216 HIS HIS A . n 
D 1 270 PHE 270 217 217 PHE PHE A . n 
D 1 271 HIS 271 218 218 HIS HIS A . n 
D 1 272 LEU 272 219 219 LEU LEU A . n 
D 1 273 LYS 273 220 220 LYS LYS A . n 
D 1 274 ARG 274 221 221 ARG ARG A . n 
D 1 275 LYS 275 222 222 LYS LYS A . n 
D 1 276 ILE 276 223 223 ILE ILE A . n 
D 1 277 GLY 277 224 224 GLY GLY A . n 
D 1 278 TYR 278 225 225 TYR TYR A . n 
D 1 279 PHE 279 226 226 PHE PHE A . n 
D 1 280 VAL 280 227 227 VAL VAL A . n 
D 1 281 ILE 281 228 228 ILE ILE A . n 
D 1 282 GLN 282 229 229 GLN GLN A . n 
D 1 283 THR 283 230 230 THR THR A . n 
D 1 284 TYR 284 231 231 TYR TYR A . n 
D 1 285 LEU 285 232 232 LEU LEU A . n 
D 1 286 PRO 286 233 233 PRO PRO A . n 
D 1 287 CYS 287 234 234 CYS CYS A . n 
D 1 288 ILE 288 235 235 ILE ILE A . n 
D 1 289 MET 289 236 236 MET MET A . n 
D 1 290 THR 290 237 237 THR THR A . n 
D 1 291 VAL 291 238 238 VAL VAL A . n 
D 1 292 ILE 292 239 239 ILE ILE A . n 
D 1 293 LEU 293 240 240 LEU LEU A . n 
D 1 294 SER 294 241 241 SER SER A . n 
D 1 295 GLN 295 242 242 GLN GLN A . n 
D 1 296 VAL 296 243 243 VAL VAL A . n 
D 1 297 SER 297 244 244 SER SER A . n 
D 1 298 PHE 298 245 245 PHE PHE A . n 
D 1 299 TRP 299 246 246 TRP TRP A . n 
D 1 300 LEU 300 247 247 LEU LEU A . n 
D 1 301 ASN 301 248 248 ASN ASN A . n 
D 1 302 ARG 302 249 249 ARG ARG A . n 
D 1 303 GLU 303 250 250 GLU GLU A . n 
D 1 304 SER 304 251 251 SER SER A . n 
D 1 305 VAL 305 252 252 VAL VAL A . n 
D 1 306 PRO 306 253 253 PRO PRO A . n 
D 1 307 ALA 307 254 254 ALA ALA A . n 
D 1 308 ARG 308 255 255 ARG ARG A . n 
D 1 309 THR 309 256 256 THR THR A . n 
D 1 310 VAL 310 257 257 VAL VAL A . n 
D 1 311 PHE 311 258 258 PHE PHE A . n 
D 1 312 GLY 312 259 259 GLY GLY A . n 
D 1 313 VAL 313 260 260 VAL VAL A . n 
D 1 314 THR 314 261 261 THR THR A . n 
D 1 315 THR 315 262 262 THR THR A . n 
D 1 316 VAL 316 263 263 VAL VAL A . n 
D 1 317 LEU 317 264 264 LEU LEU A . n 
D 1 318 THR 318 265 265 THR THR A . n 
D 1 319 MET 319 266 266 MET MET A . n 
D 1 320 THR 320 267 267 THR THR A . n 
D 1 321 THR 321 268 268 THR THR A . n 
D 1 322 LEU 322 269 269 LEU LEU A . n 
D 1 323 SER 323 270 270 SER SER A . n 
D 1 324 ILE 324 271 271 ILE ILE A . n 
D 1 325 SER 325 272 272 SER SER A . n 
D 1 326 ALA 326 273 273 ALA ALA A . n 
D 1 327 ARG 327 274 274 ARG ARG A . n 
D 1 328 ASN 328 275 275 ASN ASN A . n 
D 1 329 SER 329 276 276 SER SER A . n 
D 1 330 LEU 330 277 277 LEU LEU A . n 
D 1 331 PRO 331 278 278 PRO PRO A . n 
D 1 332 LYS 332 279 279 LYS LYS A . n 
D 1 333 VAL 333 280 280 VAL VAL A . n 
D 1 334 ALA 334 281 281 ALA ALA A . n 
D 1 335 TYR 335 282 282 TYR TYR A . n 
D 1 336 ALA 336 283 283 ALA ALA A . n 
D 1 337 THR 337 284 284 THR THR A . n 
D 1 338 ALA 338 285 285 ALA ALA A . n 
D 1 339 MET 339 286 286 MET MET A . n 
D 1 340 ASP 340 287 287 ASP ASP A . n 
D 1 341 TRP 341 288 288 TRP TRP A . n 
D 1 342 PHE 342 289 289 PHE PHE A . n 
D 1 343 ILE 343 290 290 ILE ILE A . n 
D 1 344 ALA 344 291 291 ALA ALA A . n 
D 1 345 VAL 345 292 292 VAL VAL A . n 
D 1 346 CYS 346 293 293 CYS CYS A . n 
D 1 347 TYR 347 294 294 TYR TYR A . n 
D 1 348 ALA 348 295 295 ALA ALA A . n 
D 1 349 PHE 349 296 296 PHE PHE A . n 
D 1 350 VAL 350 297 297 VAL VAL A . n 
D 1 351 PHE 351 298 298 PHE PHE A . n 
D 1 352 SER 352 299 299 SER SER A . n 
D 1 353 ALA 353 300 300 ALA ALA A . n 
D 1 354 LEU 354 301 301 LEU LEU A . n 
D 1 355 ILE 355 302 302 ILE ILE A . n 
D 1 356 GLU 356 303 303 GLU GLU A . n 
D 1 357 PHE 357 304 304 PHE PHE A . n 
D 1 358 ALA 358 305 305 ALA ALA A . n 
D 1 359 THR 359 306 306 THR THR A . n 
D 1 360 VAL 360 307 307 VAL VAL A . n 
D 1 361 ASN 361 308 308 ASN ASN A . n 
D 1 362 TYR 362 309 309 TYR TYR A . n 
D 1 363 PHE 363 310 310 PHE PHE A . n 
D 1 364 THR 364 311 311 THR THR A . n 
D 1 365 LYS 365 312 312 LYS LYS A . n 
D 1 366 SER 366 313 313 SER SER A . n 
D 1 367 GLN 367 385 385 GLN GLN A . n 
D 1 368 PRO 368 386 386 PRO PRO A . n 
D 1 369 ALA 369 387 387 ALA ALA A . n 
D 1 370 ARG 370 388 388 ARG ARG A . n 
D 1 371 ALA 371 389 389 ALA ALA A . n 
D 1 372 ALA 372 390 390 ALA ALA A . n 
D 1 373 LYS 373 391 391 LYS LYS A . n 
D 1 374 ILE 374 392 392 ILE ILE A . n 
D 1 375 ASP 375 393 393 ASP ASP A . n 
D 1 376 ARG 376 394 394 ARG ARG A . n 
D 1 377 LEU 377 395 395 LEU LEU A . n 
D 1 378 SER 378 396 396 SER SER A . n 
D 1 379 ARG 379 397 397 ARG ARG A . n 
D 1 380 ILE 380 398 398 ILE ILE A . n 
D 1 381 ALA 381 399 399 ALA ALA A . n 
D 1 382 PHE 382 400 400 PHE PHE A . n 
D 1 383 PRO 383 401 401 PRO PRO A . n 
D 1 384 LEU 384 402 402 LEU LEU A . n 
D 1 385 LEU 385 403 403 LEU LEU A . n 
D 1 386 PHE 386 404 404 PHE PHE A . n 
D 1 387 GLY 387 405 405 GLY GLY A . n 
D 1 388 ILE 388 406 406 ILE ILE A . n 
D 1 389 PHE 389 407 407 PHE PHE A . n 
D 1 390 ASN 390 408 408 ASN ASN A . n 
D 1 391 LEU 391 409 409 LEU LEU A . n 
D 1 392 VAL 392 410 410 VAL VAL A . n 
D 1 393 TYR 393 411 411 TYR TYR A . n 
D 1 394 TRP 394 412 412 TRP TRP A . n 
D 1 395 ALA 395 413 413 ALA ALA A . n 
D 1 396 THR 396 414 414 THR THR A . n 
D 1 397 TYR 397 415 415 TYR TYR A . n 
D 1 398 LEU 398 416 416 LEU LEU A . n 
D 1 399 ASN 399 417 417 ASN ASN A . n 
D 1 400 ARG 400 418 418 ARG ARG A . n 
D 1 401 GLU 401 419 ?   ?   ?   A . n 
D 1 402 PRO 402 420 ?   ?   ?   A . n 
D 1 403 GLN 403 421 ?   ?   ?   A . n 
D 1 404 LEU 404 422 ?   ?   ?   A . n 
D 1 405 LYS 405 423 ?   ?   ?   A . n 
D 1 406 ALA 406 424 ?   ?   ?   A . n 
D 1 407 PRO 407 425 ?   ?   ?   A . n 
D 1 408 THR 408 426 ?   ?   ?   A . n 
D 1 409 PRO 409 427 ?   ?   ?   A . n 
D 1 410 HIS 410 428 ?   ?   ?   A . n 
D 1 411 GLN 411 429 ?   ?   ?   A . n 
E 2 1   MET 1   -53 ?   ?   ?   C . n 
E 2 2   ASP 2   -52 ?   ?   ?   C . n 
E 2 3   GLU 3   -51 ?   ?   ?   C . n 
E 2 4   LYS 4   -50 ?   ?   ?   C . n 
E 2 5   THR 5   -49 ?   ?   ?   C . n 
E 2 6   THR 6   -48 ?   ?   ?   C . n 
E 2 7   GLY 7   -47 ?   ?   ?   C . n 
E 2 8   TRP 8   -46 ?   ?   ?   C . n 
E 2 9   ARG 9   -45 ?   ?   ?   C . n 
E 2 10  GLY 10  -44 ?   ?   ?   C . n 
E 2 11  GLY 11  -43 ?   ?   ?   C . n 
E 2 12  HIS 12  -42 ?   ?   ?   C . n 
E 2 13  VAL 13  -41 ?   ?   ?   C . n 
E 2 14  VAL 14  -40 ?   ?   ?   C . n 
E 2 15  GLU 15  -39 ?   ?   ?   C . n 
E 2 16  GLY 16  -38 ?   ?   ?   C . n 
E 2 17  LEU 17  -37 ?   ?   ?   C . n 
E 2 18  ALA 18  -36 ?   ?   ?   C . n 
E 2 19  GLY 19  -35 ?   ?   ?   C . n 
E 2 20  GLU 20  -34 ?   ?   ?   C . n 
E 2 21  LEU 21  -33 ?   ?   ?   C . n 
E 2 22  GLU 22  -32 ?   ?   ?   C . n 
E 2 23  GLN 23  -31 ?   ?   ?   C . n 
E 2 24  LEU 24  -30 ?   ?   ?   C . n 
E 2 25  ARG 25  -29 ?   ?   ?   C . n 
E 2 26  ALA 26  -28 ?   ?   ?   C . n 
E 2 27  ARG 27  -27 ?   ?   ?   C . n 
E 2 28  LEU 28  -26 ?   ?   ?   C . n 
E 2 29  GLU 29  -25 ?   ?   ?   C . n 
E 2 30  HIS 30  -24 ?   ?   ?   C . n 
E 2 31  HIS 31  -23 ?   ?   ?   C . n 
E 2 32  PRO 32  -22 ?   ?   ?   C . n 
E 2 33  GLN 33  -21 ?   ?   ?   C . n 
E 2 34  GLY 34  -20 ?   ?   ?   C . n 
E 2 35  GLN 35  -19 ?   ?   ?   C . n 
E 2 36  ARG 36  -18 ?   ?   ?   C . n 
E 2 37  GLU 37  -17 ?   ?   ?   C . n 
E 2 38  PRO 38  -16 ?   ?   ?   C . n 
E 2 39  ASP 39  -15 ?   ?   ?   C . n 
E 2 40  TYR 40  -14 ?   ?   ?   C . n 
E 2 41  ASP 41  -13 ?   ?   ?   C . n 
E 2 42  ILE 42  -12 ?   ?   ?   C . n 
E 2 43  PRO 43  -11 ?   ?   ?   C . n 
E 2 44  THR 44  -10 ?   ?   ?   C . n 
E 2 45  THR 45  -9  ?   ?   ?   C . n 
E 2 46  GLU 46  -8  ?   ?   ?   C . n 
E 2 47  ASN 47  -7  ?   ?   ?   C . n 
E 2 48  LEU 48  -6  ?   ?   ?   C . n 
E 2 49  TYR 49  -5  ?   ?   ?   C . n 
E 2 50  PHE 50  -4  ?   ?   ?   C . n 
E 2 51  GLN 51  -3  ?   ?   ?   C . n 
E 2 52  GLY 52  -2  ?   ?   ?   C . n 
E 2 53  THR 53  -1  ?   ?   ?   C . n 
E 2 54  GLY 54  0   ?   ?   ?   C . n 
E 2 55  GLN 55  1   ?   ?   ?   C . n 
E 2 56  SER 56  2   ?   ?   ?   C . n 
E 2 57  VAL 57  3   ?   ?   ?   C . n 
E 2 58  ASN 58  4   ?   ?   ?   C . n 
E 2 59  ASP 59  5   ?   ?   ?   C . n 
E 2 60  PRO 60  6   ?   ?   ?   C . n 
E 2 61  GLY 61  7   ?   ?   ?   C . n 
E 2 62  ASN 62  8   8   ASN ASN C . n 
E 2 63  MET 63  9   9   MET MET C . n 
E 2 64  SER 64  10  10  SER SER C . n 
E 2 65  PHE 65  11  11  PHE PHE C . n 
E 2 66  VAL 66  12  12  VAL VAL C . n 
E 2 67  LYS 67  13  13  LYS LYS C . n 
E 2 68  GLU 68  14  14  GLU GLU C . n 
E 2 69  THR 69  15  15  THR THR C . n 
E 2 70  VAL 70  16  16  VAL VAL C . n 
E 2 71  ASP 71  17  17  ASP ASP C . n 
E 2 72  LYS 72  18  18  LYS LYS C . n 
E 2 73  LEU 73  19  19  LEU LEU C . n 
E 2 74  LEU 74  20  20  LEU LEU C . n 
E 2 75  LYS 75  21  21  LYS LYS C . n 
E 2 76  GLY 76  22  22  GLY GLY C . n 
E 2 77  TYR 77  23  23  TYR TYR C . n 
E 2 78  ASP 78  24  24  ASP ASP C . n 
E 2 79  ILE 79  25  25  ILE ILE C . n 
E 2 80  ARG 80  26  26  ARG ARG C . n 
E 2 81  LEU 81  27  27  LEU LEU C . n 
E 2 82  ARG 82  28  28  ARG ARG C . n 
E 2 83  PRO 83  29  29  PRO PRO C . n 
E 2 84  ASP 84  30  30  ASP ASP C . n 
E 2 85  PHE 85  31  31  PHE PHE C . n 
E 2 86  GLY 86  32  32  GLY GLY C . n 
E 2 87  GLY 87  33  33  GLY GLY C . n 
E 2 88  PRO 88  34  34  PRO PRO C . n 
E 2 89  PRO 89  35  35  PRO PRO C . n 
E 2 90  VAL 90  36  36  VAL VAL C . n 
E 2 91  CYS 91  37  37  CYS CYS C . n 
E 2 92  VAL 92  38  38  VAL VAL C . n 
E 2 93  GLY 93  39  39  GLY GLY C . n 
E 2 94  MET 94  40  40  MET MET C . n 
E 2 95  ASN 95  41  41  ASN ASN C . n 
E 2 96  ILE 96  42  42  ILE ILE C . n 
E 2 97  ASP 97  43  43  ASP ASP C . n 
E 2 98  ILE 98  44  44  ILE ILE C . n 
E 2 99  ALA 99  45  45  ALA ALA C . n 
E 2 100 SER 100 46  46  SER SER C . n 
E 2 101 ILE 101 47  47  ILE ILE C . n 
E 2 102 ASP 102 48  48  ASP ASP C . n 
E 2 103 MET 103 49  49  MET MET C . n 
E 2 104 VAL 104 50  50  VAL VAL C . n 
E 2 105 SER 105 51  51  SER SER C . n 
E 2 106 GLU 106 52  52  GLU GLU C . n 
E 2 107 VAL 107 53  53  VAL VAL C . n 
E 2 108 ASN 108 54  54  ASN ASN C . n 
E 2 109 MET 109 55  55  MET MET C . n 
E 2 110 ASP 110 56  56  ASP ASP C . n 
E 2 111 TYR 111 57  57  TYR TYR C . n 
E 2 112 THR 112 58  58  THR THR C . n 
E 2 113 LEU 113 59  59  LEU LEU C . n 
E 2 114 THR 114 60  60  THR THR C . n 
E 2 115 MET 115 61  61  MET MET C . n 
E 2 116 TYR 116 62  62  TYR TYR C . n 
E 2 117 PHE 117 63  63  PHE PHE C . n 
E 2 118 GLN 118 64  64  GLN GLN C . n 
E 2 119 GLN 119 65  65  GLN GLN C . n 
E 2 120 TYR 120 66  66  TYR TYR C . n 
E 2 121 TRP 121 67  67  TRP TRP C . n 
E 2 122 ARG 122 68  68  ARG ARG C . n 
E 2 123 ASP 123 69  69  ASP ASP C . n 
E 2 124 LYS 124 70  70  LYS LYS C . n 
E 2 125 ARG 125 71  71  ARG ARG C . n 
E 2 126 LEU 126 72  72  LEU LEU C . n 
E 2 127 ALA 127 73  73  ALA ALA C . n 
E 2 128 TYR 128 74  74  TYR TYR C . n 
E 2 129 SER 129 75  75  SER SER C . n 
E 2 130 GLY 130 76  76  GLY GLY C . n 
E 2 131 ILE 131 77  77  ILE ILE C . n 
E 2 132 PRO 132 78  78  PRO PRO C . n 
E 2 133 LEU 133 79  79  LEU LEU C . n 
E 2 134 ASN 134 80  80  ASN ASN C . n 
E 2 135 LEU 135 81  81  LEU LEU C . n 
E 2 136 THR 136 82  82  THR THR C . n 
E 2 137 LEU 137 83  83  LEU LEU C . n 
E 2 138 ASP 138 84  84  ASP ASP C . n 
E 2 139 ASN 139 85  85  ASN ASN C . n 
E 2 140 ARG 140 86  86  ARG ARG C . n 
E 2 141 VAL 141 87  87  VAL VAL C . n 
E 2 142 ALA 142 88  88  ALA ALA C . n 
E 2 143 ASP 143 89  89  ASP ASP C . n 
E 2 144 GLN 144 90  90  GLN GLN C . n 
E 2 145 LEU 145 91  91  LEU LEU C . n 
E 2 146 TRP 146 92  92  TRP TRP C . n 
E 2 147 VAL 147 93  93  VAL VAL C . n 
E 2 148 PRO 148 94  94  PRO PRO C . n 
E 2 149 ASP 149 95  95  ASP ASP C . n 
E 2 150 THR 150 96  96  THR THR C . n 
E 2 151 TYR 151 97  97  TYR TYR C . n 
E 2 152 PHE 152 98  98  PHE PHE C . n 
E 2 153 LEU 153 99  99  LEU LEU C . n 
E 2 154 ASN 154 100 100 ASN ASN C . n 
E 2 155 ASP 155 101 101 ASP ASP C . n 
E 2 156 LYS 156 102 102 LYS LYS C . n 
E 2 157 LYS 157 103 103 LYS LYS C . n 
E 2 158 SER 158 104 104 SER SER C . n 
E 2 159 PHE 159 105 105 PHE PHE C . n 
E 2 160 VAL 160 106 106 VAL VAL C . n 
E 2 161 HIS 161 107 107 HIS HIS C . n 
E 2 162 GLY 162 108 108 GLY GLY C . n 
E 2 163 VAL 163 109 109 VAL VAL C . n 
E 2 164 THR 164 110 110 THR THR C . n 
E 2 165 VAL 165 111 111 VAL VAL C . n 
E 2 166 LYS 166 112 112 LYS LYS C . n 
E 2 167 ASN 167 113 113 ASN ASN C . n 
E 2 168 ARG 168 114 114 ARG ARG C . n 
E 2 169 MET 169 115 115 MET MET C . n 
E 2 170 ILE 170 116 116 ILE ILE C . n 
E 2 171 ARG 171 117 117 ARG ARG C . n 
E 2 172 LEU 172 118 118 LEU LEU C . n 
E 2 173 HIS 173 119 119 HIS HIS C . n 
E 2 174 PRO 174 120 120 PRO PRO C . n 
E 2 175 ASP 175 121 121 ASP ASP C . n 
E 2 176 GLY 176 122 122 GLY GLY C . n 
E 2 177 THR 177 123 123 THR THR C . n 
E 2 178 VAL 178 124 124 VAL VAL C . n 
E 2 179 LEU 179 125 125 LEU LEU C . n 
E 2 180 TYR 180 126 126 TYR TYR C . n 
E 2 181 GLY 181 127 127 GLY GLY C . n 
E 2 182 LEU 182 128 128 LEU LEU C . n 
E 2 183 ARG 183 129 129 ARG ARG C . n 
E 2 184 ILE 184 130 130 ILE ILE C . n 
E 2 185 THR 185 131 131 THR THR C . n 
E 2 186 THR 186 132 132 THR THR C . n 
E 2 187 THR 187 133 133 THR THR C . n 
E 2 188 ALA 188 134 134 ALA ALA C . n 
E 2 189 ALA 189 135 135 ALA ALA C . n 
E 2 190 CYS 190 136 136 CYS CYS C . n 
E 2 191 MET 191 137 137 MET MET C . n 
E 2 192 MET 192 138 138 MET MET C . n 
E 2 193 ASP 193 139 139 ASP ASP C . n 
E 2 194 LEU 194 140 140 LEU LEU C . n 
E 2 195 ARG 195 141 141 ARG ARG C . n 
E 2 196 ARG 196 142 142 ARG ARG C . n 
E 2 197 TYR 197 143 143 TYR TYR C . n 
E 2 198 PRO 198 144 144 PRO PRO C . n 
E 2 199 LEU 199 145 145 LEU LEU C . n 
E 2 200 ASP 200 146 146 ASP ASP C . n 
E 2 201 GLU 201 147 147 GLU GLU C . n 
E 2 202 GLN 202 148 148 GLN GLN C . n 
E 2 203 ASN 203 149 149 ASN ASN C . n 
E 2 204 CYS 204 150 150 CYS CYS C . n 
E 2 205 THR 205 151 151 THR THR C . n 
E 2 206 LEU 206 152 152 LEU LEU C . n 
E 2 207 GLU 207 153 153 GLU GLU C . n 
E 2 208 ILE 208 154 154 ILE ILE C . n 
E 2 209 GLU 209 155 155 GLU GLU C . n 
E 2 210 SER 210 156 156 SER SER C . n 
E 2 211 TYR 211 157 157 TYR TYR C . n 
E 2 212 GLY 212 158 158 GLY GLY C . n 
E 2 213 TYR 213 159 159 TYR TYR C . n 
E 2 214 THR 214 160 160 THR THR C . n 
E 2 215 THR 215 161 161 THR THR C . n 
E 2 216 ASP 216 162 162 ASP ASP C . n 
E 2 217 ASP 217 163 163 ASP ASP C . n 
E 2 218 ILE 218 164 164 ILE ILE C . n 
E 2 219 GLU 219 165 165 GLU GLU C . n 
E 2 220 PHE 220 166 166 PHE PHE C . n 
E 2 221 TYR 221 167 167 TYR TYR C . n 
E 2 222 TRP 222 168 168 TRP TRP C . n 
E 2 223 ARG 223 169 169 ARG ARG C . n 
E 2 224 GLY 224 170 170 GLY GLY C . n 
E 2 225 GLY 225 171 171 GLY GLY C . n 
E 2 226 ASP 226 172 172 ASP ASP C . n 
E 2 227 LYS 227 173 173 LYS LYS C . n 
E 2 228 ALA 228 174 174 ALA ALA C . n 
E 2 229 VAL 229 175 175 VAL VAL C . n 
E 2 230 THR 230 176 176 THR THR C . n 
E 2 231 GLY 231 177 177 GLY GLY C . n 
E 2 232 VAL 232 178 178 VAL VAL C . n 
E 2 233 GLU 233 179 179 GLU GLU C . n 
E 2 234 ARG 234 180 180 ARG ARG C . n 
E 2 235 ILE 235 181 181 ILE ILE C . n 
E 2 236 GLU 236 182 182 GLU GLU C . n 
E 2 237 LEU 237 183 183 LEU LEU C . n 
E 2 238 PRO 238 184 184 PRO PRO C . n 
E 2 239 GLN 239 185 185 GLN GLN C . n 
E 2 240 PHE 240 186 186 PHE PHE C . n 
E 2 241 SER 241 187 187 SER SER C . n 
E 2 242 ILE 242 188 188 ILE ILE C . n 
E 2 243 VAL 243 189 189 VAL VAL C . n 
E 2 244 GLU 244 190 190 GLU GLU C . n 
E 2 245 HIS 245 191 191 HIS HIS C . n 
E 2 246 ARG 246 192 192 ARG ARG C . n 
E 2 247 LEU 247 193 193 LEU LEU C . n 
E 2 248 VAL 248 194 194 VAL VAL C . n 
E 2 249 SER 249 195 195 SER SER C . n 
E 2 250 ARG 250 196 196 ARG ARG C . n 
E 2 251 ASN 251 197 197 ASN ASN C . n 
E 2 252 VAL 252 198 198 VAL VAL C . n 
E 2 253 VAL 253 199 199 VAL VAL C . n 
E 2 254 PHE 254 200 200 PHE PHE C . n 
E 2 255 ALA 255 201 201 ALA ALA C . n 
E 2 256 THR 256 202 202 THR THR C . n 
E 2 257 GLY 257 203 203 GLY GLY C . n 
E 2 258 ALA 258 204 204 ALA ALA C . n 
E 2 259 TYR 259 205 205 TYR TYR C . n 
E 2 260 PRO 260 206 206 PRO PRO C . n 
E 2 261 ARG 261 207 207 ARG ARG C . n 
E 2 262 LEU 262 208 208 LEU LEU C . n 
E 2 263 SER 263 209 209 SER SER C . n 
E 2 264 LEU 264 210 210 LEU LEU C . n 
E 2 265 SER 265 211 211 SER SER C . n 
E 2 266 PHE 266 212 212 PHE PHE C . n 
E 2 267 ARG 267 213 213 ARG ARG C . n 
E 2 268 LEU 268 214 214 LEU LEU C . n 
E 2 269 LYS 269 215 215 LYS LYS C . n 
E 2 270 ARG 270 216 216 ARG ARG C . n 
E 2 271 ASN 271 217 217 ASN ASN C . n 
E 2 272 ILE 272 218 218 ILE ILE C . n 
E 2 273 GLY 273 219 219 GLY GLY C . n 
E 2 274 TYR 274 220 220 TYR TYR C . n 
E 2 275 PHE 275 221 221 PHE PHE C . n 
E 2 276 ILE 276 222 222 ILE ILE C . n 
E 2 277 LEU 277 223 223 LEU LEU C . n 
E 2 278 GLN 278 224 224 GLN GLN C . n 
E 2 279 THR 279 225 225 THR THR C . n 
E 2 280 TYR 280 226 226 TYR TYR C . n 
E 2 281 MET 281 227 227 MET MET C . n 
E 2 282 PRO 282 228 228 PRO PRO C . n 
E 2 283 SER 283 229 229 SER SER C . n 
E 2 284 ILE 284 230 230 ILE ILE C . n 
E 2 285 LEU 285 231 231 LEU LEU C . n 
E 2 286 ILE 286 232 232 ILE ILE C . n 
E 2 287 THR 287 233 233 THR THR C . n 
E 2 288 ILE 288 234 234 ILE ILE C . n 
E 2 289 LEU 289 235 235 LEU LEU C . n 
E 2 290 SER 290 236 236 SER SER C . n 
E 2 291 TRP 291 237 237 TRP TRP C . n 
E 2 292 VAL 292 238 238 VAL VAL C . n 
E 2 293 SER 293 239 239 SER SER C . n 
E 2 294 PHE 294 240 240 PHE PHE C . n 
E 2 295 TRP 295 241 241 TRP TRP C . n 
E 2 296 ILE 296 242 242 ILE ILE C . n 
E 2 297 ASN 297 243 243 ASN ASN C . n 
E 2 298 TYR 298 244 244 TYR TYR C . n 
E 2 299 ASP 299 245 245 ASP ASP C . n 
E 2 300 ALA 300 246 246 ALA ALA C . n 
E 2 301 SER 301 247 247 SER SER C . n 
E 2 302 ALA 302 248 248 ALA ALA C . n 
E 2 303 ALA 303 249 249 ALA ALA C . n 
E 2 304 ARG 304 250 250 ARG ARG C . n 
E 2 305 VAL 305 251 251 VAL VAL C . n 
E 2 306 ALA 306 252 252 ALA ALA C . n 
E 2 307 LEU 307 253 253 LEU LEU C . n 
E 2 308 GLY 308 254 254 GLY GLY C . n 
E 2 309 ILE 309 255 255 ILE ILE C . n 
E 2 310 THR 310 256 256 THR THR C . n 
E 2 311 THR 311 257 257 THR THR C . n 
E 2 312 VAL 312 258 258 VAL VAL C . n 
E 2 313 LEU 313 259 259 LEU LEU C . n 
E 2 314 THR 314 260 260 THR THR C . n 
E 2 315 MET 315 261 261 MET MET C . n 
E 2 316 THR 316 262 262 THR THR C . n 
E 2 317 THR 317 263 263 THR THR C . n 
E 2 318 ILE 318 264 264 ILE ILE C . n 
E 2 319 ASN 319 265 265 ASN ASN C . n 
E 2 320 THR 320 266 266 THR THR C . n 
E 2 321 HIS 321 267 267 HIS HIS C . n 
E 2 322 LEU 322 268 268 LEU LEU C . n 
E 2 323 ARG 323 269 269 ARG ARG C . n 
E 2 324 GLU 324 270 270 GLU GLU C . n 
E 2 325 THR 325 271 271 THR THR C . n 
E 2 326 LEU 326 272 272 LEU LEU C . n 
E 2 327 PRO 327 273 273 PRO PRO C . n 
E 2 328 LYS 328 274 274 LYS LYS C . n 
E 2 329 ILE 329 275 275 ILE ILE C . n 
E 2 330 PRO 330 276 276 PRO PRO C . n 
E 2 331 TYR 331 277 277 TYR TYR C . n 
E 2 332 VAL 332 278 278 VAL VAL C . n 
E 2 333 LYS 333 279 279 LYS LYS C . n 
E 2 334 ALA 334 280 280 ALA ALA C . n 
E 2 335 ILE 335 281 281 ILE ILE C . n 
E 2 336 ASP 336 282 282 ASP ASP C . n 
E 2 337 MET 337 283 283 MET MET C . n 
E 2 338 TYR 338 284 284 TYR TYR C . n 
E 2 339 LEU 339 285 285 LEU LEU C . n 
E 2 340 MET 340 286 286 MET MET C . n 
E 2 341 GLY 341 287 287 GLY GLY C . n 
E 2 342 CYS 342 288 288 CYS CYS C . n 
E 2 343 PHE 343 289 289 PHE PHE C . n 
E 2 344 VAL 344 290 290 VAL VAL C . n 
E 2 345 PHE 345 291 291 PHE PHE C . n 
E 2 346 VAL 346 292 292 VAL VAL C . n 
E 2 347 PHE 347 293 293 PHE PHE C . n 
E 2 348 LEU 348 294 294 LEU LEU C . n 
E 2 349 ALA 349 295 295 ALA ALA C . n 
E 2 350 LEU 350 296 296 LEU LEU C . n 
E 2 351 LEU 351 297 297 LEU LEU C . n 
E 2 352 GLU 352 298 298 GLU GLU C . n 
E 2 353 TYR 353 299 299 TYR TYR C . n 
E 2 354 ALA 354 300 300 ALA ALA C . n 
E 2 355 PHE 355 301 301 PHE PHE C . n 
E 2 356 VAL 356 302 302 VAL VAL C . n 
E 2 357 ASN 357 303 303 ASN ASN C . n 
E 2 358 TYR 358 304 304 TYR TYR C . n 
E 2 359 ILE 359 305 305 ILE ILE C . n 
E 2 360 PHE 360 306 306 PHE PHE C . n 
E 2 361 PHE 361 307 307 PHE PHE C . n 
E 2 362 SER 362 308 308 SER SER C . n 
E 2 363 GLN 363 309 309 GLN GLN C . n 
E 2 364 PRO 364 310 310 PRO PRO C . n 
E 2 365 ALA 365 311 311 ALA ALA C . n 
E 2 366 ARG 366 312 312 ARG ARG C . n 
E 2 367 ALA 367 313 313 ALA ALA C . n 
E 2 368 ALA 368 314 314 ALA ALA C . n 
E 2 369 ALA 369 422 422 ALA ALA C . n 
E 2 370 ILE 370 423 423 ILE ILE C . n 
E 2 371 ASP 371 424 424 ASP ASP C . n 
E 2 372 ARG 372 425 425 ARG ARG C . n 
E 2 373 TRP 373 426 426 TRP TRP C . n 
E 2 374 SER 374 427 427 SER SER C . n 
E 2 375 ARG 375 428 428 ARG ARG C . n 
E 2 376 ILE 376 429 429 ILE ILE C . n 
E 2 377 VAL 377 430 430 VAL VAL C . n 
E 2 378 PHE 378 431 431 PHE PHE C . n 
E 2 379 PRO 379 432 432 PRO PRO C . n 
E 2 380 PHE 380 433 433 PHE PHE C . n 
E 2 381 THR 381 434 434 THR THR C . n 
E 2 382 PHE 382 435 435 PHE PHE C . n 
E 2 383 SER 383 436 436 SER SER C . n 
E 2 384 LEU 384 437 437 LEU LEU C . n 
E 2 385 PHE 385 438 438 PHE PHE C . n 
E 2 386 ASN 386 439 439 ASN ASN C . n 
E 2 387 LEU 387 440 440 LEU LEU C . n 
E 2 388 VAL 388 441 441 VAL VAL C . n 
E 2 389 TYR 389 442 442 TYR TYR C . n 
E 2 390 TRP 390 443 443 TRP TRP C . n 
E 2 391 LEU 391 444 444 LEU LEU C . n 
E 2 392 TYR 392 445 445 TYR TYR C . n 
E 2 393 TYR 393 446 446 TYR TYR C . n 
E 2 394 VAL 394 447 447 VAL VAL C . n 
E 2 395 ASN 395 448 ?   ?   ?   C . n 
F 3 1   GLN 1   2   2   GLN GLN F . n 
F 3 2   VAL 2   3   3   VAL VAL F . n 
F 3 3   GLN 3   4   4   GLN GLN F . n 
F 3 4   LEU 4   5   5   LEU LEU F . n 
F 3 5   VAL 5   6   6   VAL VAL F . n 
F 3 6   GLU 6   7   7   GLU GLU F . n 
F 3 7   SER 7   8   8   SER SER F . n 
F 3 8   GLY 8   9   9   GLY GLY F . n 
F 3 9   GLY 9   10  ?   ?   ?   F . n 
F 3 10  GLY 10  11  ?   ?   ?   F . n 
F 3 11  LEU 11  12  ?   ?   ?   F . n 
F 3 12  VAL 12  13  ?   ?   ?   F . n 
F 3 13  GLN 13  14  ?   ?   ?   F . n 
F 3 14  THR 14  15  ?   ?   ?   F . n 
F 3 15  LYS 15  16  ?   ?   ?   F . n 
F 3 16  THR 16  17  ?   ?   ?   F . n 
F 3 17  THR 17  18  ?   ?   ?   F . n 
F 3 18  THR 18  19  ?   ?   ?   F . n 
F 3 19  SER 19  20  ?   ?   ?   F . n 
F 3 20  VAL 20  21  ?   ?   ?   F . n 
F 3 21  ILE 21  22  ?   ?   ?   F . n 
F 3 22  ASP 22  23  ?   ?   ?   F . n 
F 3 23  THR 23  24  ?   ?   ?   F . n 
F 3 24  THR 24  25  ?   ?   ?   F . n 
F 3 25  ASN 25  26  ?   ?   ?   F . n 
F 3 26  ASP 26  27  ?   ?   ?   F . n 
F 3 27  ALA 27  28  ?   ?   ?   F . n 
F 3 28  GLN 28  29  ?   ?   ?   F . n 
F 3 29  ASN 29  30  ?   ?   ?   F . n 
F 3 30  LEU 30  31  ?   ?   ?   F . n 
F 3 31  LEU 31  32  ?   ?   ?   F . n 
F 3 32  THR 32  33  ?   ?   ?   F . n 
F 3 33  GLN 33  34  ?   ?   ?   F . n 
F 3 34  ALA 34  35  ?   ?   ?   F . n 
F 3 35  GLN 35  36  ?   ?   ?   F . n 
F 3 36  THR 36  37  ?   ?   ?   F . n 
F 3 37  ILE 37  38  ?   ?   ?   F . n 
F 3 38  VAL 38  39  ?   ?   ?   F . n 
F 3 39  ASN 39  40  ?   ?   ?   F . n 
F 3 40  THR 40  41  ?   ?   ?   F . n 
F 3 41  LEU 41  42  ?   ?   ?   F . n 
F 3 42  LYS 42  43  ?   ?   ?   F . n 
F 3 43  ASP 43  44  ?   ?   ?   F . n 
F 3 44  TYR 44  45  ?   ?   ?   F . n 
F 3 45  CYS 45  46  ?   ?   ?   F . n 
F 3 46  PRO 46  47  ?   ?   ?   F . n 
F 3 47  ILE 47  48  ?   ?   ?   F . n 
F 3 48  LEU 48  49  ?   ?   ?   F . n 
F 3 49  ILE 49  50  ?   ?   ?   F . n 
F 3 50  ALA 50  51  ?   ?   ?   F . n 
F 3 51  LYS 51  52  ?   ?   ?   F . n 
F 3 52  SER 52  53  ?   ?   ?   F . n 
F 3 53  SER 53  54  ?   ?   ?   F . n 
F 3 54  SER 54  55  ?   ?   ?   F . n 
F 3 55  SER 55  56  ?   ?   ?   F . n 
F 3 56  ASN 56  57  ?   ?   ?   F . n 
F 3 57  GLY 57  58  ?   ?   ?   F . n 
F 3 58  GLY 58  59  ?   ?   ?   F . n 
F 3 59  THR 59  60  ?   ?   ?   F . n 
F 3 60  ASN 60  61  ?   ?   ?   F . n 
F 3 61  ASN 61  62  ?   ?   ?   F . n 
F 3 62  ALA 62  63  ?   ?   ?   F . n 
F 3 63  ASN 63  64  ?   ?   ?   F . n 
F 3 64  THR 64  65  ?   ?   ?   F . n 
F 3 65  PRO 65  66  ?   ?   ?   F . n 
F 3 66  SER 66  67  ?   ?   ?   F . n 
F 3 67  TRP 67  68  ?   ?   ?   F . n 
F 3 68  GLN 68  69  ?   ?   ?   F . n 
F 3 69  THR 69  70  ?   ?   ?   F . n 
F 3 70  ALA 70  71  ?   ?   ?   F . n 
F 3 71  GLY 71  72  ?   ?   ?   F . n 
F 3 72  GLY 72  73  ?   ?   ?   F . n 
F 3 73  GLY 73  74  ?   ?   ?   F . n 
F 3 74  LYS 74  75  ?   ?   ?   F . n 
F 3 75  ASN 75  76  ?   ?   ?   F . n 
F 3 76  SER 76  77  ?   ?   ?   F . n 
F 3 77  CYS 77  78  ?   ?   ?   F . n 
F 3 78  ALA 78  79  ?   ?   ?   F . n 
F 3 79  THR 79  80  ?   ?   ?   F . n 
F 3 80  PHE 80  81  ?   ?   ?   F . n 
F 3 81  GLY 81  82  ?   ?   ?   F . n 
F 3 82  ALA 82  83  ?   ?   ?   F . n 
F 3 83  GLU 83  84  ?   ?   ?   F . n 
F 3 84  PHE 84  85  ?   ?   ?   F . n 
F 3 85  SER 85  86  ?   ?   ?   F . n 
F 3 86  ALA 86  87  ?   ?   ?   F . n 
F 3 87  ALA 87  88  ?   ?   ?   F . n 
F 3 88  SER 88  89  ?   ?   ?   F . n 
F 3 89  ASP 89  90  ?   ?   ?   F . n 
F 3 90  MET 90  91  ?   ?   ?   F . n 
F 3 91  ILE 91  92  ?   ?   ?   F . n 
F 3 92  ASN 92  93  ?   ?   ?   F . n 
F 3 93  ASN 93  94  ?   ?   ?   F . n 
F 3 94  ALA 94  95  ?   ?   ?   F . n 
F 3 95  GLN 95  96  ?   ?   ?   F . n 
F 3 96  LYS 96  97  ?   ?   ?   F . n 
F 3 97  ILE 97  98  ?   ?   ?   F . n 
F 3 98  VAL 98  99  ?   ?   ?   F . n 
F 3 99  GLN 99  100 ?   ?   ?   F . n 
F 3 100 GLU 100 101 ?   ?   ?   F . n 
F 3 101 THR 101 102 ?   ?   ?   F . n 
F 3 102 GLN 102 103 ?   ?   ?   F . n 
F 3 103 GLN 103 104 ?   ?   ?   F . n 
F 3 104 LEU 104 105 ?   ?   ?   F . n 
F 3 105 SER 105 106 ?   ?   ?   F . n 
F 3 106 ALA 106 107 ?   ?   ?   F . n 
F 3 107 ASN 107 108 ?   ?   ?   F . n 
F 3 108 GLN 108 109 ?   ?   ?   F . n 
F 3 109 PRO 109 110 ?   ?   ?   F . n 
F 3 110 LYS 110 111 ?   ?   ?   F . n 
F 3 111 ASN 111 112 ?   ?   ?   F . n 
F 3 112 ILE 112 113 ?   ?   ?   F . n 
F 3 113 THR 113 114 ?   ?   ?   F . n 
F 3 114 GLN 114 115 ?   ?   ?   F . n 
F 3 115 PRO 115 116 ?   ?   ?   F . n 
F 3 116 HIS 116 117 ?   ?   ?   F . n 
F 3 117 ASN 117 118 ?   ?   ?   F . n 
F 3 118 LEU 118 119 ?   ?   ?   F . n 
F 3 119 ASN 119 120 ?   ?   ?   F . n 
F 3 120 LEU 120 121 ?   ?   ?   F . n 
F 3 121 ASN 121 122 ?   ?   ?   F . n 
F 3 122 SER 122 123 ?   ?   ?   F . n 
F 3 123 PRO 123 124 ?   ?   ?   F . n 
F 3 124 SER 124 125 ?   ?   ?   F . n 
F 3 125 SER 125 126 ?   ?   ?   F . n 
F 3 126 LEU 126 127 ?   ?   ?   F . n 
F 3 127 THR 127 128 ?   ?   ?   F . n 
F 3 128 ALA 128 129 ?   ?   ?   F . n 
F 3 129 LEU 129 130 ?   ?   ?   F . n 
F 3 130 ALA 130 131 ?   ?   ?   F . n 
F 3 131 GLN 131 132 ?   ?   ?   F . n 
F 3 132 LYS 132 133 ?   ?   ?   F . n 
F 3 133 MET 133 134 ?   ?   ?   F . n 
F 3 134 LEU 134 135 ?   ?   ?   F . n 
F 3 135 LYS 135 136 ?   ?   ?   F . n 
F 3 136 ASN 136 137 ?   ?   ?   F . n 
F 3 137 ALA 137 138 ?   ?   ?   F . n 
F 3 138 GLN 138 139 ?   ?   ?   F . n 
F 3 139 SER 139 140 ?   ?   ?   F . n 
F 3 140 GLN 140 141 ?   ?   ?   F . n 
F 3 141 ALA 141 142 ?   ?   ?   F . n 
F 3 142 GLU 142 143 ?   ?   ?   F . n 
F 3 143 ILE 143 144 ?   ?   ?   F . n 
F 3 144 LEU 144 145 ?   ?   ?   F . n 
F 3 145 LYS 145 146 ?   ?   ?   F . n 
F 3 146 LEU 146 147 ?   ?   ?   F . n 
F 3 147 ALA 147 148 ?   ?   ?   F . n 
F 3 148 ASN 148 149 ?   ?   ?   F . n 
F 3 149 GLN 149 150 ?   ?   ?   F . n 
F 3 150 VAL 150 151 ?   ?   ?   F . n 
F 3 151 GLU 151 152 ?   ?   ?   F . n 
F 3 152 SER 152 153 ?   ?   ?   F . n 
F 3 153 ASP 153 154 ?   ?   ?   F . n 
F 3 154 PHE 154 155 ?   ?   ?   F . n 
F 3 155 ASN 155 156 ?   ?   ?   F . n 
F 3 156 LYS 156 157 ?   ?   ?   F . n 
F 3 157 LEU 157 158 ?   ?   ?   F . n 
F 3 158 SER 158 159 ?   ?   ?   F . n 
F 3 159 SER 159 160 ?   ?   ?   F . n 
F 3 160 GLY 160 161 ?   ?   ?   F . n 
F 3 161 HIS 161 162 ?   ?   ?   F . n 
F 3 162 LEU 162 163 ?   ?   ?   F . n 
F 3 163 LYS 163 164 ?   ?   ?   F . n 
F 3 164 ASP 164 165 ?   ?   ?   F . n 
F 3 165 TYR 165 166 ?   ?   ?   F . n 
F 3 166 ILE 166 167 ?   ?   ?   F . n 
F 3 167 GLY 167 168 ?   ?   ?   F . n 
F 3 168 LYS 168 169 ?   ?   ?   F . n 
F 3 169 CYS 169 170 ?   ?   ?   F . n 
F 3 170 ASP 170 171 ?   ?   ?   F . n 
F 3 171 ALA 171 172 ?   ?   ?   F . n 
F 3 172 SER 172 173 ?   ?   ?   F . n 
F 3 173 ALA 173 174 ?   ?   ?   F . n 
F 3 174 ILE 174 175 ?   ?   ?   F . n 
F 3 175 SER 175 176 ?   ?   ?   F . n 
F 3 176 SER 176 177 ?   ?   ?   F . n 
F 3 177 ALA 177 178 ?   ?   ?   F . n 
F 3 178 ASN 178 179 ?   ?   ?   F . n 
F 3 179 MET 179 180 ?   ?   ?   F . n 
F 3 180 THR 180 181 ?   ?   ?   F . n 
F 3 181 MET 181 182 ?   ?   ?   F . n 
F 3 182 GLN 182 183 ?   ?   ?   F . n 
F 3 183 ASN 183 184 ?   ?   ?   F . n 
F 3 184 GLN 184 185 ?   ?   ?   F . n 
F 3 185 LYS 185 186 ?   ?   ?   F . n 
F 3 186 ASN 186 187 ?   ?   ?   F . n 
F 3 187 ASN 187 188 ?   ?   ?   F . n 
F 3 188 TRP 188 189 ?   ?   ?   F . n 
F 3 189 GLY 189 190 ?   ?   ?   F . n 
F 3 190 ASN 190 191 ?   ?   ?   F . n 
F 3 191 GLY 191 192 ?   ?   ?   F . n 
F 3 192 CYS 192 193 ?   ?   ?   F . n 
F 3 193 ALA 193 194 ?   ?   ?   F . n 
F 3 194 GLY 194 195 ?   ?   ?   F . n 
F 3 195 VAL 195 196 ?   ?   ?   F . n 
F 3 196 GLU 196 197 ?   ?   ?   F . n 
F 3 197 GLU 197 198 ?   ?   ?   F . n 
F 3 198 THR 198 199 ?   ?   ?   F . n 
F 3 199 GLN 199 200 ?   ?   ?   F . n 
F 3 200 SER 200 201 ?   ?   ?   F . n 
F 3 201 LEU 201 202 ?   ?   ?   F . n 
F 3 202 LEU 202 203 ?   ?   ?   F . n 
F 3 203 LYS 203 204 ?   ?   ?   F . n 
F 3 204 THR 204 205 ?   ?   ?   F . n 
F 3 205 SER 205 206 ?   ?   ?   F . n 
F 3 206 ALA 206 207 ?   ?   ?   F . n 
F 3 207 ALA 207 208 ?   ?   ?   F . n 
F 3 208 ASP 208 209 ?   ?   ?   F . n 
F 3 209 PHE 209 210 ?   ?   ?   F . n 
F 3 210 ASN 210 211 ?   ?   ?   F . n 
F 3 211 ASN 211 212 ?   ?   ?   F . n 
F 3 212 GLN 212 213 ?   ?   ?   F . n 
F 3 213 THR 213 214 ?   ?   ?   F . n 
F 3 214 PRO 214 215 ?   ?   ?   F . n 
F 3 215 GLN 215 216 ?   ?   ?   F . n 
F 3 216 ILE 216 217 ?   ?   ?   F . n 
F 3 217 ASN 217 218 ?   ?   ?   F . n 
F 3 218 GLN 218 219 ?   ?   ?   F . n 
F 3 219 ALA 219 220 ?   ?   ?   F . n 
F 3 220 GLN 220 221 ?   ?   ?   F . n 
F 3 221 ASN 221 222 ?   ?   ?   F . n 
F 3 222 LEU 222 223 ?   ?   ?   F . n 
F 3 223 ALA 223 224 ?   ?   ?   F . n 
F 3 224 ASN 224 225 ?   ?   ?   F . n 
F 3 225 THR 225 226 ?   ?   ?   F . n 
F 3 226 LEU 226 227 ?   ?   ?   F . n 
F 3 227 ILE 227 228 ?   ?   ?   F . n 
F 3 228 GLN 228 229 ?   ?   ?   F . n 
F 3 229 GLU 229 230 ?   ?   ?   F . n 
F 3 230 LEU 230 231 ?   ?   ?   F . n 
F 3 231 GLY 231 232 ?   ?   ?   F . n 
F 3 232 ASN 232 233 ?   ?   ?   F . n 
F 3 233 ASN 233 234 ?   ?   ?   F . n 
F 3 234 THR 234 235 ?   ?   ?   F . n 
F 3 235 TYR 235 236 ?   ?   ?   F . n 
F 3 236 GLU 236 237 ?   ?   ?   F . n 
F 3 237 GLN 237 238 ?   ?   ?   F . n 
F 3 238 LEU 238 239 ?   ?   ?   F . n 
F 3 239 SER 239 240 ?   ?   ?   F . n 
F 3 240 ARG 240 241 ?   ?   ?   F . n 
F 3 241 LEU 241 242 ?   ?   ?   F . n 
F 3 242 LEU 242 243 ?   ?   ?   F . n 
F 3 243 THR 243 244 ?   ?   ?   F . n 
F 3 244 ASN 244 245 ?   ?   ?   F . n 
F 3 245 ASP 245 246 ?   ?   ?   F . n 
F 3 246 ASN 246 247 ?   ?   ?   F . n 
F 3 247 GLY 247 248 ?   ?   ?   F . n 
F 3 248 THR 248 249 ?   ?   ?   F . n 
F 3 249 ASN 249 250 ?   ?   ?   F . n 
F 3 250 SER 250 251 ?   ?   ?   F . n 
F 3 251 LYS 251 252 ?   ?   ?   F . n 
F 3 252 THR 252 253 ?   ?   ?   F . n 
F 3 253 SER 253 254 ?   ?   ?   F . n 
F 3 254 ALA 254 255 ?   ?   ?   F . n 
F 3 255 GLN 255 256 ?   ?   ?   F . n 
F 3 256 ALA 256 257 ?   ?   ?   F . n 
F 3 257 ILE 257 258 ?   ?   ?   F . n 
F 3 258 ASN 258 259 ?   ?   ?   F . n 
F 3 259 GLN 259 260 ?   ?   ?   F . n 
F 3 260 ALA 260 261 ?   ?   ?   F . n 
F 3 261 VAL 261 262 ?   ?   ?   F . n 
F 3 262 ASN 262 263 ?   ?   ?   F . n 
F 3 263 ASN 263 264 ?   ?   ?   F . n 
F 3 264 LEU 264 265 ?   ?   ?   F . n 
F 3 265 ASN 265 266 ?   ?   ?   F . n 
F 3 266 GLU 266 267 ?   ?   ?   F . n 
F 3 267 ARG 267 268 ?   ?   ?   F . n 
F 3 268 ALA 268 269 ?   ?   ?   F . n 
F 3 269 LYS 269 270 ?   ?   ?   F . n 
F 3 270 THR 270 271 ?   ?   ?   F . n 
F 3 271 LEU 271 272 ?   ?   ?   F . n 
F 3 272 ALA 272 273 ?   ?   ?   F . n 
F 3 273 GLY 273 274 ?   ?   ?   F . n 
F 3 274 GLY 274 275 ?   ?   ?   F . n 
F 3 275 THR 275 276 ?   ?   ?   F . n 
F 3 276 THR 276 277 ?   ?   ?   F . n 
F 3 277 ASN 277 278 ?   ?   ?   F . n 
F 3 278 SER 278 279 ?   ?   ?   F . n 
F 3 279 PRO 279 280 ?   ?   ?   F . n 
F 3 280 ALA 280 281 ?   ?   ?   F . n 
F 3 281 TYR 281 282 ?   ?   ?   F . n 
F 3 282 GLN 282 283 ?   ?   ?   F . n 
F 3 283 ALA 283 284 ?   ?   ?   F . n 
F 3 284 THR 284 285 ?   ?   ?   F . n 
F 3 285 LEU 285 286 ?   ?   ?   F . n 
F 3 286 LEU 286 287 ?   ?   ?   F . n 
F 3 287 ALA 287 288 ?   ?   ?   F . n 
F 3 288 LEU 288 289 ?   ?   ?   F . n 
F 3 289 ARG 289 290 ?   ?   ?   F . n 
F 3 290 SER 290 291 ?   ?   ?   F . n 
F 3 291 VAL 291 292 ?   ?   ?   F . n 
F 3 292 LEU 292 293 ?   ?   ?   F . n 
F 3 293 GLY 293 294 ?   ?   ?   F . n 
F 3 294 LEU 294 295 ?   ?   ?   F . n 
F 3 295 TRP 295 296 ?   ?   ?   F . n 
F 3 296 ASN 296 297 ?   ?   ?   F . n 
F 3 297 SER 297 298 ?   ?   ?   F . n 
F 3 298 MET 298 299 ?   ?   ?   F . n 
F 3 299 GLY 299 300 ?   ?   ?   F . n 
F 3 300 TYR 300 301 ?   ?   ?   F . n 
F 3 301 ALA 301 302 ?   ?   ?   F . n 
F 3 302 VAL 302 303 ?   ?   ?   F . n 
F 3 303 ILE 303 304 ?   ?   ?   F . n 
F 3 304 CYS 304 305 ?   ?   ?   F . n 
F 3 305 GLY 305 306 ?   ?   ?   F . n 
F 3 306 GLY 306 307 ?   ?   ?   F . n 
F 3 307 TYR 307 308 ?   ?   ?   F . n 
F 3 308 THR 308 309 ?   ?   ?   F . n 
F 3 309 LYS 309 310 ?   ?   ?   F . n 
F 3 310 SER 310 311 ?   ?   ?   F . n 
F 3 311 PRO 311 312 ?   ?   ?   F . n 
F 3 312 GLY 312 313 ?   ?   ?   F . n 
F 3 313 GLU 313 314 ?   ?   ?   F . n 
F 3 314 ASN 314 315 ?   ?   ?   F . n 
F 3 315 ASN 315 316 ?   ?   ?   F . n 
F 3 316 GLN 316 317 ?   ?   ?   F . n 
F 3 317 LYS 317 318 ?   ?   ?   F . n 
F 3 318 ASP 318 319 ?   ?   ?   F . n 
F 3 319 PHE 319 320 ?   ?   ?   F . n 
F 3 320 HIS 320 321 ?   ?   ?   F . n 
F 3 321 TYR 321 322 ?   ?   ?   F . n 
F 3 322 THR 322 323 ?   ?   ?   F . n 
F 3 323 ASP 323 324 ?   ?   ?   F . n 
F 3 324 GLU 324 325 ?   ?   ?   F . n 
F 3 325 ASN 325 326 ?   ?   ?   F . n 
F 3 326 GLY 326 327 ?   ?   ?   F . n 
F 3 327 ASN 327 328 ?   ?   ?   F . n 
F 3 328 GLY 328 329 ?   ?   ?   F . n 
F 3 329 THR 329 330 ?   ?   ?   F . n 
F 3 330 THR 330 331 ?   ?   ?   F . n 
F 3 331 ILE 331 332 ?   ?   ?   F . n 
F 3 332 ASN 332 333 ?   ?   ?   F . n 
F 3 333 CYS 333 334 ?   ?   ?   F . n 
F 3 334 GLY 334 335 ?   ?   ?   F . n 
F 3 335 GLY 335 336 ?   ?   ?   F . n 
F 3 336 SER 336 337 ?   ?   ?   F . n 
F 3 337 THR 337 338 ?   ?   ?   F . n 
F 3 338 ASN 338 339 ?   ?   ?   F . n 
F 3 339 SER 339 340 ?   ?   ?   F . n 
F 3 340 ASN 340 341 ?   ?   ?   F . n 
F 3 341 GLY 341 342 ?   ?   ?   F . n 
F 3 342 THR 342 343 ?   ?   ?   F . n 
F 3 343 HIS 343 344 ?   ?   ?   F . n 
F 3 344 SER 344 345 ?   ?   ?   F . n 
F 3 345 TYR 345 346 ?   ?   ?   F . n 
F 3 346 ASN 346 347 ?   ?   ?   F . n 
F 3 347 GLY 347 348 ?   ?   ?   F . n 
F 3 348 THR 348 349 ?   ?   ?   F . n 
F 3 349 ASN 349 350 ?   ?   ?   F . n 
F 3 350 THR 350 351 ?   ?   ?   F . n 
F 3 351 LEU 351 352 ?   ?   ?   F . n 
F 3 352 LYS 352 353 ?   ?   ?   F . n 
F 3 353 ALA 353 354 ?   ?   ?   F . n 
F 3 354 ASP 354 355 ?   ?   ?   F . n 
F 3 355 LYS 355 356 ?   ?   ?   F . n 
F 3 356 ASN 356 357 ?   ?   ?   F . n 
F 3 357 VAL 357 358 ?   ?   ?   F . n 
F 3 358 SER 358 359 ?   ?   ?   F . n 
F 3 359 LEU 359 360 ?   ?   ?   F . n 
F 3 360 SER 360 361 ?   ?   ?   F . n 
F 3 361 ILE 361 362 ?   ?   ?   F . n 
F 3 362 GLU 362 363 ?   ?   ?   F . n 
F 3 363 GLN 363 364 ?   ?   ?   F . n 
F 3 364 TYR 364 365 ?   ?   ?   F . n 
F 3 365 GLU 365 366 ?   ?   ?   F . n 
F 3 366 LYS 366 367 ?   ?   ?   F . n 
F 3 367 ILE 367 368 ?   ?   ?   F . n 
F 3 368 HIS 368 369 ?   ?   ?   F . n 
F 3 369 GLU 369 370 ?   ?   ?   F . n 
F 3 370 ALA 370 371 ?   ?   ?   F . n 
F 3 371 TYR 371 372 ?   ?   ?   F . n 
F 3 372 GLN 372 373 ?   ?   ?   F . n 
F 3 373 ILE 373 374 ?   ?   ?   F . n 
F 3 374 LEU 374 375 ?   ?   ?   F . n 
F 3 375 SER 375 376 ?   ?   ?   F . n 
F 3 376 LYS 376 377 ?   ?   ?   F . n 
F 3 377 ALA 377 378 ?   ?   ?   F . n 
F 3 378 LEU 378 379 ?   ?   ?   F . n 
F 3 379 LYS 379 380 ?   ?   ?   F . n 
F 3 380 GLN 380 381 ?   ?   ?   F . n 
F 3 381 ALA 381 382 ?   ?   ?   F . n 
F 3 382 GLY 382 383 ?   ?   ?   F . n 
F 3 383 LEU 383 384 ?   ?   ?   F . n 
F 3 384 ALA 384 385 ?   ?   ?   F . n 
F 3 385 PRO 385 386 ?   ?   ?   F . n 
F 3 386 LEU 386 387 ?   ?   ?   F . n 
F 3 387 ASN 387 388 ?   ?   ?   F . n 
F 3 388 SER 388 389 ?   ?   ?   F . n 
F 3 389 LYS 389 390 ?   ?   ?   F . n 
F 3 390 GLY 390 391 ?   ?   ?   F . n 
F 3 391 GLU 391 392 ?   ?   ?   F . n 
F 3 392 LYS 392 393 ?   ?   ?   F . n 
F 3 393 LEU 393 394 ?   ?   ?   F . n 
F 3 394 GLU 394 395 ?   ?   ?   F . n 
F 3 395 ALA 395 396 ?   ?   ?   F . n 
F 3 396 HIS 396 397 ?   ?   ?   F . n 
F 3 397 VAL 397 398 ?   ?   ?   F . n 
F 3 398 THR 398 399 ?   ?   ?   F . n 
F 3 399 THR 399 400 ?   ?   ?   F . n 
F 3 400 SER 400 401 ?   ?   ?   F . n 
F 3 401 LYS 401 402 ?   ?   ?   F . n 
F 3 402 TYR 402 403 ?   ?   ?   F . n 
F 3 403 GLY 403 404 ?   ?   ?   F . n 
F 3 404 SER 404 405 ?   ?   ?   F . n 
F 3 405 LEU 405 406 406 LEU LEU F . n 
F 3 406 ARG 406 407 407 ARG ARG F . n 
F 3 407 LEU 407 408 408 LEU LEU F . n 
F 3 408 SER 408 409 409 SER SER F . n 
F 3 409 CYS 409 410 410 CYS CYS F . n 
F 3 410 ALA 410 411 411 ALA ALA F . n 
F 3 411 ALA 411 412 412 ALA ALA F . n 
F 3 412 SER 412 413 413 SER SER F . n 
F 3 413 GLY 413 414 414 GLY GLY F . n 
F 3 414 HIS 414 415 415 HIS HIS F . n 
F 3 415 THR 415 416 416 THR THR F . n 
F 3 416 PHE 416 417 417 PHE PHE F . n 
F 3 417 ASN 417 418 418 ASN ASN F . n 
F 3 418 TYR 418 419 419 TYR TYR F . n 
F 3 419 PRO 419 420 420 PRO PRO F . n 
F 3 420 ILE 420 421 421 ILE ILE F . n 
F 3 421 MET 421 422 422 MET MET F . n 
F 3 422 GLY 422 423 423 GLY GLY F . n 
F 3 423 TRP 423 424 424 TRP TRP F . n 
F 3 424 PHE 424 425 425 PHE PHE F . n 
F 3 425 ARG 425 426 426 ARG ARG F . n 
F 3 426 GLN 426 427 427 GLN GLN F . n 
F 3 427 ALA 427 428 428 ALA ALA F . n 
F 3 428 PRO 428 429 429 PRO PRO F . n 
F 3 429 GLY 429 430 430 GLY GLY F . n 
F 3 430 LYS 430 431 431 LYS LYS F . n 
F 3 431 GLU 431 432 432 GLU GLU F . n 
F 3 432 ARG 432 433 433 ARG ARG F . n 
F 3 433 GLU 433 434 434 GLU GLU F . n 
F 3 434 PHE 434 435 435 PHE PHE F . n 
F 3 435 VAL 435 436 436 VAL VAL F . n 
F 3 436 GLY 436 437 437 GLY GLY F . n 
F 3 437 ALA 437 438 438 ALA ALA F . n 
F 3 438 ILE 438 439 439 ILE ILE F . n 
F 3 439 SER 439 440 440 SER SER F . n 
F 3 440 TRP 440 441 441 TRP TRP F . n 
F 3 441 SER 441 442 442 SER SER F . n 
F 3 442 GLY 442 443 443 GLY GLY F . n 
F 3 443 GLY 443 444 444 GLY GLY F . n 
F 3 444 SER 444 445 445 SER SER F . n 
F 3 445 THR 445 446 446 THR THR F . n 
F 3 446 SER 446 447 447 SER SER F . n 
F 3 447 TYR 447 448 448 TYR TYR F . n 
F 3 448 ALA 448 449 449 ALA ALA F . n 
F 3 449 ASP 449 450 450 ASP ASP F . n 
F 3 450 SER 450 451 451 SER SER F . n 
F 3 451 VAL 451 452 452 VAL VAL F . n 
F 3 452 LYS 452 453 453 LYS LYS F . n 
F 3 453 ASP 453 454 454 ASP ASP F . n 
F 3 454 ARG 454 455 455 ARG ARG F . n 
F 3 455 PHE 455 456 456 PHE PHE F . n 
F 3 456 THR 456 457 457 THR THR F . n 
F 3 457 ILE 457 458 458 ILE ILE F . n 
F 3 458 SER 458 459 459 SER SER F . n 
F 3 459 ARG 459 460 460 ARG ARG F . n 
F 3 460 ASP 460 461 461 ASP ASP F . n 
F 3 461 ASN 461 462 462 ASN ASN F . n 
F 3 462 ALA 462 463 463 ALA ALA F . n 
F 3 463 LYS 463 464 464 LYS LYS F . n 
F 3 464 ASN 464 465 465 ASN ASN F . n 
F 3 465 THR 465 466 466 THR THR F . n 
F 3 466 VAL 466 467 467 VAL VAL F . n 
F 3 467 TYR 467 468 468 TYR TYR F . n 
F 3 468 LEU 468 469 469 LEU LEU F . n 
F 3 469 GLU 469 470 470 GLU GLU F . n 
F 3 470 MET 470 471 471 MET MET F . n 
F 3 471 ASN 471 472 472 ASN ASN F . n 
F 3 472 ASN 472 473 473 ASN ASN F . n 
F 3 473 LEU 473 474 474 LEU LEU F . n 
F 3 474 LYS 474 475 475 LYS LYS F . n 
F 3 475 PRO 475 476 476 PRO PRO F . n 
F 3 476 GLU 476 477 477 GLU GLU F . n 
F 3 477 ASP 477 478 478 ASP ASP F . n 
F 3 478 THR 478 479 479 THR THR F . n 
F 3 479 ALA 479 480 480 ALA ALA F . n 
F 3 480 VAL 480 481 481 VAL VAL F . n 
F 3 481 TYR 481 482 482 TYR TYR F . n 
F 3 482 TYR 482 483 483 TYR TYR F . n 
F 3 483 CYS 483 484 484 CYS CYS F . n 
F 3 484 ALA 484 485 485 ALA ALA F . n 
F 3 485 ALA 485 486 486 ALA ALA F . n 
F 3 486 LYS 486 487 487 LYS LYS F . n 
F 3 487 GLY 487 488 488 GLY GLY F . n 
F 3 488 ARG 488 489 489 ARG ARG F . n 
F 3 489 TYR 489 490 490 TYR TYR F . n 
F 3 490 SER 490 491 491 SER SER F . n 
F 3 491 GLY 491 492 492 GLY GLY F . n 
F 3 492 GLY 492 493 493 GLY GLY F . n 
F 3 493 LEU 493 494 494 LEU LEU F . n 
F 3 494 TYR 494 495 495 TYR TYR F . n 
F 3 495 TYR 495 496 496 TYR TYR F . n 
F 3 496 PRO 496 497 497 PRO PRO F . n 
F 3 497 THR 497 498 498 THR THR F . n 
F 3 498 ASN 498 499 499 ASN ASN F . n 
F 3 499 TYR 499 500 500 TYR TYR F . n 
F 3 500 ASP 500 501 501 ASP ASP F . n 
F 3 501 TYR 501 502 502 TYR TYR F . n 
F 3 502 TRP 502 503 503 TRP TRP F . n 
F 3 503 GLY 503 504 504 GLY GLY F . n 
F 3 504 GLN 504 505 505 GLN GLN F . n 
F 3 505 GLY 505 506 506 GLY GLY F . n 
F 3 506 THR 506 507 507 THR THR F . n 
F 3 507 GLN 507 508 508 GLN GLN F . n 
F 3 508 VAL 508 509 509 VAL VAL F . n 
F 3 509 THR 509 510 510 THR THR F . n 
F 3 510 VAL 510 511 ?   ?   ?   F . n 
F 3 511 SER 511 512 ?   ?   ?   F . n 
F 3 512 SER 512 513 ?   ?   ?   F . n 
F 3 513 HIS 513 514 ?   ?   ?   F . n 
F 3 514 HIS 514 515 ?   ?   ?   F . n 
F 3 515 HIS 515 516 ?   ?   ?   F . n 
F 3 516 HIS 516 517 ?   ?   ?   F . n 
F 3 517 HIS 517 518 ?   ?   ?   F . n 
F 3 518 HIS 518 519 ?   ?   ?   F . n 
F 3 519 GLU 519 520 ?   ?   ?   F . n 
F 3 520 PRO 520 521 ?   ?   ?   F . n 
F 3 521 GLU 521 522 ?   ?   ?   F . n 
F 3 522 ALA 522 523 ?   ?   ?   F . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
G 4 NAG 1 a NAG 1 a NAG 1 n 
G 4 NAG 2 a NAG 2 a NAG 2 n 
G 4 BMA 3 a BMA 3 a BMA 3 n 
G 4 MAN 4 a MAN 4 a MAN 5 n 
G 4 MAN 5 a MAN 5 a MAN 4 n 
H 4 NAG 1 b NAG 1 b NAG 1 n 
H 4 NAG 2 b NAG 2 b NAG 2 n 
H 4 BMA 3 b BMA 3 b BMA 3 n 
H 4 MAN 4 b MAN 4 b MAN 4 n 
H 4 MAN 5 b MAN 5 b MAN 5 n 
I 5 NAG 1 G NAG 1 b NAG 6 n 
I 5 NAG 2 G NAG 2 b NAG 7 n 
J 4 NAG 1 c NAG 1 c NAG 1 n 
J 4 NAG 2 c NAG 2 c NAG 2 n 
J 4 BMA 3 c BMA 3 c BMA 3 n 
J 4 MAN 4 c MAN 4 c MAN 4 n 
J 4 MAN 5 c MAN 5 c MAN 5 n 
K 5 NAG 1 H NAG 1 c NAG 6 n 
K 5 NAG 2 H NAG 2 c NAG 7 n 
L 4 NAG 1 d NAG 1 d NAG 1 n 
L 4 NAG 2 d NAG 2 d NAG 2 n 
L 4 BMA 3 d BMA 3 d BMA 3 n 
L 4 MAN 4 d MAN 4 d MAN 5 n 
L 4 MAN 5 d MAN 5 d MAN 4 n 
M 4 NAG 1 e NAG 1 e NAG 1 n 
M 4 NAG 2 e NAG 2 e NAG 2 n 
M 4 BMA 3 e BMA 3 e BMA 3 n 
M 4 MAN 4 e MAN 4 e MAN 4 n 
M 4 MAN 5 e MAN 5 e MAN 5 n 
N 5 NAG 1 I NAG 1 e NAG 6 n 
N 5 NAG 2 I NAG 2 e NAG 7 n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        ABU 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   ABU 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
O 6 CL  1 501 2 CL  CL  D . 
P 7 ABU 1 501 2 ABU ABU E . 
Q 7 ABU 1 501 1 ABU ABU B . 
R 6 CL  1 501 1 CL  CL  A . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FFQ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FFQ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FFQ 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9FFQ 
_struct.title                        
;Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric desensitised state of branch 1
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FFQ 
_struct_keywords.text            'GABA, neurotransmission, gating cycle, time-resolved cryo-EM, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
I N N 5 ? 
J N N 4 ? 
K N N 5 ? 
L N N 4 ? 
M N N 4 ? 
N N N 5 ? 
O N N 6 ? 
P N N 7 ? 
Q N N 7 ? 
R N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GBRA1_HUMAN  P14867 ? 1 
;QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL
RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTR
AEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK
;
32  
2 UNP GBRA1_HUMAN  P14867 ? 1 KIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 418 
3 UNP GBRB3_HUMAN  P28472 ? 2 
;QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLN
LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYT
TDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF
WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF
;
26  
4 UNP GBRB3_HUMAN  P28472 ? 2 AIDRWSRIVFPFTFSLFNLVYWLYYVN 447 
5 PDB 9FFQ         9FFQ   ? 3 ? 1   
6 UNP B5Z8H1_HELPG B5Z8H1 ? 3 
;QTKTTTSVIDTTNDAQNLLTQAQTIVNTLKDYCPILIAKSSSSNGGTNNANTPSWQTAGGGKNSCATFGAEFSAASDMIN
NAQKIVQETQQLSANQPKNITQPHNLNLNSPSSLTALAQKMLKNAQSQAEILKLANQVESDFNKLSSGHLKDYIGKCDAS
AISSANMTMQNQKNNWGNGCAGVEETQSLLKTSAADFNNQTPQINQAQNLANTLIQELGNN
;
226 
7 UNP B5Z8H1_HELPG B5Z8H1 ? 3 
;TYEQLSRLLTNDNGTNSKTSAQAINQAVNNLNERAKTLAGGTTNSPAYQATLLALRSVLGLWNSMGYAVICGGYTKSPGE
NNQKDFHYTDENGNGTTINCGGSTNSNGTHSYNGTNTLKADKNVSLSIEQYEKIHEAYQILSKALKQAGLAPLNSKGEKL
EAHVTTSKY
;
53  
8 PDB 9FFQ         9FFQ   ? 3 ? 403 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1  1 9FFQ D 58  ? 365 ? P14867 32  ? 339 ? 5   312 
2  2 9FFQ D 373 ? 411 ? P14867 418 ? 456 ? 391 429 
3  3 9FFQ E 55  ? 361 ? P28472 26  ? 332 ? 1   307 
4  4 9FFQ E 369 ? 395 ? P28472 447 ? 473 ? 422 448 
5  3 9FFQ B 55  ? 361 ? P28472 26  ? 332 ? 1   307 
6  4 9FFQ B 369 ? 395 ? P28472 447 ? 473 ? 422 448 
7  1 9FFQ A 58  ? 365 ? P14867 32  ? 339 ? 5   312 
8  2 9FFQ A 373 ? 411 ? P14867 418 ? 456 ? 391 429 
9  3 9FFQ C 55  ? 361 ? P28472 26  ? 332 ? 1   307 
10 4 9FFQ C 369 ? 395 ? P28472 447 ? 473 ? 422 448 
11 5 9FFQ F 1   ? 12  ? 9FFQ   2   ? 13  ? 2   13  
12 6 9FFQ F 13  ? 233 ? B5Z8H1 226 ? 446 ? 14  234 
13 7 9FFQ F 234 ? 402 ? B5Z8H1 53  ? 221 ? 235 403 
14 8 9FFQ F 403 ? 522 ? 9FFQ   404 ? 523 ? 404 523 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9FFQ MET D 1   ? UNP P14867 ? ? 'initiating methionine' -52 1   
1 9FFQ ASP D 2   ? UNP P14867 ? ? 'expression tag'        -51 2   
1 9FFQ GLU D 3   ? UNP P14867 ? ? 'expression tag'        -50 3   
1 9FFQ LYS D 4   ? UNP P14867 ? ? 'expression tag'        -49 4   
1 9FFQ THR D 5   ? UNP P14867 ? ? 'expression tag'        -48 5   
1 9FFQ THR D 6   ? UNP P14867 ? ? 'expression tag'        -47 6   
1 9FFQ GLY D 7   ? UNP P14867 ? ? 'expression tag'        -46 7   
1 9FFQ TRP D 8   ? UNP P14867 ? ? 'expression tag'        -45 8   
1 9FFQ ARG D 9   ? UNP P14867 ? ? 'expression tag'        -44 9   
1 9FFQ GLY D 10  ? UNP P14867 ? ? 'expression tag'        -43 10  
1 9FFQ GLY D 11  ? UNP P14867 ? ? 'expression tag'        -42 11  
1 9FFQ HIS D 12  ? UNP P14867 ? ? 'expression tag'        -41 12  
1 9FFQ VAL D 13  ? UNP P14867 ? ? 'expression tag'        -40 13  
1 9FFQ VAL D 14  ? UNP P14867 ? ? 'expression tag'        -39 14  
1 9FFQ GLU D 15  ? UNP P14867 ? ? 'expression tag'        -38 15  
1 9FFQ GLY D 16  ? UNP P14867 ? ? 'expression tag'        -37 16  
1 9FFQ LEU D 17  ? UNP P14867 ? ? 'expression tag'        -36 17  
1 9FFQ ALA D 18  ? UNP P14867 ? ? 'expression tag'        -35 18  
1 9FFQ GLY D 19  ? UNP P14867 ? ? 'expression tag'        -34 19  
1 9FFQ GLU D 20  ? UNP P14867 ? ? 'expression tag'        -33 20  
1 9FFQ LEU D 21  ? UNP P14867 ? ? 'expression tag'        -32 21  
1 9FFQ GLU D 22  ? UNP P14867 ? ? 'expression tag'        -31 22  
1 9FFQ GLN D 23  ? UNP P14867 ? ? 'expression tag'        -30 23  
1 9FFQ LEU D 24  ? UNP P14867 ? ? 'expression tag'        -29 24  
1 9FFQ ARG D 25  ? UNP P14867 ? ? 'expression tag'        -28 25  
1 9FFQ ALA D 26  ? UNP P14867 ? ? 'expression tag'        -27 26  
1 9FFQ ARG D 27  ? UNP P14867 ? ? 'expression tag'        -26 27  
1 9FFQ LEU D 28  ? UNP P14867 ? ? 'expression tag'        -25 28  
1 9FFQ GLU D 29  ? UNP P14867 ? ? 'expression tag'        -24 29  
1 9FFQ HIS D 30  ? UNP P14867 ? ? 'expression tag'        -23 30  
1 9FFQ HIS D 31  ? UNP P14867 ? ? 'expression tag'        -22 31  
1 9FFQ PRO D 32  ? UNP P14867 ? ? 'expression tag'        -21 32  
1 9FFQ GLN D 33  ? UNP P14867 ? ? 'expression tag'        -20 33  
1 9FFQ GLY D 34  ? UNP P14867 ? ? 'expression tag'        -19 34  
1 9FFQ GLN D 35  ? UNP P14867 ? ? 'expression tag'        -18 35  
1 9FFQ ARG D 36  ? UNP P14867 ? ? 'expression tag'        -17 36  
1 9FFQ GLU D 37  ? UNP P14867 ? ? 'expression tag'        -16 37  
1 9FFQ PRO D 38  ? UNP P14867 ? ? 'expression tag'        -15 38  
1 9FFQ ASP D 39  ? UNP P14867 ? ? 'expression tag'        -14 39  
1 9FFQ TYR D 40  ? UNP P14867 ? ? 'expression tag'        -13 40  
1 9FFQ ASP D 41  ? UNP P14867 ? ? 'expression tag'        -12 41  
1 9FFQ ILE D 42  ? UNP P14867 ? ? 'expression tag'        -11 42  
1 9FFQ PRO D 43  ? UNP P14867 ? ? 'expression tag'        -10 43  
1 9FFQ THR D 44  ? UNP P14867 ? ? 'expression tag'        -9  44  
1 9FFQ THR D 45  ? UNP P14867 ? ? 'expression tag'        -8  45  
1 9FFQ GLU D 46  ? UNP P14867 ? ? 'expression tag'        -7  46  
1 9FFQ ASN D 47  ? UNP P14867 ? ? 'expression tag'        -6  47  
1 9FFQ LEU D 48  ? UNP P14867 ? ? 'expression tag'        -5  48  
1 9FFQ TYR D 49  ? UNP P14867 ? ? 'expression tag'        -4  49  
1 9FFQ PHE D 50  ? UNP P14867 ? ? 'expression tag'        -3  50  
1 9FFQ GLN D 51  ? UNP P14867 ? ? 'expression tag'        -2  51  
1 9FFQ GLY D 52  ? UNP P14867 ? ? 'expression tag'        -1  52  
1 9FFQ THR D 53  ? UNP P14867 ? ? 'expression tag'        0   53  
1 9FFQ GLY D 54  ? UNP P14867 ? ? 'expression tag'        1   54  
1 9FFQ GLN D 55  ? UNP P14867 ? ? 'expression tag'        2   55  
1 9FFQ PRO D 56  ? UNP P14867 ? ? 'expression tag'        3   56  
1 9FFQ SER D 57  ? UNP P14867 ? ? 'expression tag'        4   57  
1 9FFQ SER D 366 ? UNP P14867 ? ? linker                  313 58  
1 9FFQ GLN D 367 ? UNP P14867 ? ? linker                  385 59  
1 9FFQ PRO D 368 ? UNP P14867 ? ? linker                  386 60  
1 9FFQ ALA D 369 ? UNP P14867 ? ? linker                  387 61  
1 9FFQ ARG D 370 ? UNP P14867 ? ? linker                  388 62  
1 9FFQ ALA D 371 ? UNP P14867 ? ? linker                  389 63  
1 9FFQ ALA D 372 ? UNP P14867 ? ? linker                  390 64  
3 9FFQ MET E 1   ? UNP P28472 ? ? 'initiating methionine' -53 65  
3 9FFQ ASP E 2   ? UNP P28472 ? ? 'expression tag'        -52 66  
3 9FFQ GLU E 3   ? UNP P28472 ? ? 'expression tag'        -51 67  
3 9FFQ LYS E 4   ? UNP P28472 ? ? 'expression tag'        -50 68  
3 9FFQ THR E 5   ? UNP P28472 ? ? 'expression tag'        -49 69  
3 9FFQ THR E 6   ? UNP P28472 ? ? 'expression tag'        -48 70  
3 9FFQ GLY E 7   ? UNP P28472 ? ? 'expression tag'        -47 71  
3 9FFQ TRP E 8   ? UNP P28472 ? ? 'expression tag'        -46 72  
3 9FFQ ARG E 9   ? UNP P28472 ? ? 'expression tag'        -45 73  
3 9FFQ GLY E 10  ? UNP P28472 ? ? 'expression tag'        -44 74  
3 9FFQ GLY E 11  ? UNP P28472 ? ? 'expression tag'        -43 75  
3 9FFQ HIS E 12  ? UNP P28472 ? ? 'expression tag'        -42 76  
3 9FFQ VAL E 13  ? UNP P28472 ? ? 'expression tag'        -41 77  
3 9FFQ VAL E 14  ? UNP P28472 ? ? 'expression tag'        -40 78  
3 9FFQ GLU E 15  ? UNP P28472 ? ? 'expression tag'        -39 79  
3 9FFQ GLY E 16  ? UNP P28472 ? ? 'expression tag'        -38 80  
3 9FFQ LEU E 17  ? UNP P28472 ? ? 'expression tag'        -37 81  
3 9FFQ ALA E 18  ? UNP P28472 ? ? 'expression tag'        -36 82  
3 9FFQ GLY E 19  ? UNP P28472 ? ? 'expression tag'        -35 83  
3 9FFQ GLU E 20  ? UNP P28472 ? ? 'expression tag'        -34 84  
3 9FFQ LEU E 21  ? UNP P28472 ? ? 'expression tag'        -33 85  
3 9FFQ GLU E 22  ? UNP P28472 ? ? 'expression tag'        -32 86  
3 9FFQ GLN E 23  ? UNP P28472 ? ? 'expression tag'        -31 87  
3 9FFQ LEU E 24  ? UNP P28472 ? ? 'expression tag'        -30 88  
3 9FFQ ARG E 25  ? UNP P28472 ? ? 'expression tag'        -29 89  
3 9FFQ ALA E 26  ? UNP P28472 ? ? 'expression tag'        -28 90  
3 9FFQ ARG E 27  ? UNP P28472 ? ? 'expression tag'        -27 91  
3 9FFQ LEU E 28  ? UNP P28472 ? ? 'expression tag'        -26 92  
3 9FFQ GLU E 29  ? UNP P28472 ? ? 'expression tag'        -25 93  
3 9FFQ HIS E 30  ? UNP P28472 ? ? 'expression tag'        -24 94  
3 9FFQ HIS E 31  ? UNP P28472 ? ? 'expression tag'        -23 95  
3 9FFQ PRO E 32  ? UNP P28472 ? ? 'expression tag'        -22 96  
3 9FFQ GLN E 33  ? UNP P28472 ? ? 'expression tag'        -21 97  
3 9FFQ GLY E 34  ? UNP P28472 ? ? 'expression tag'        -20 98  
3 9FFQ GLN E 35  ? UNP P28472 ? ? 'expression tag'        -19 99  
3 9FFQ ARG E 36  ? UNP P28472 ? ? 'expression tag'        -18 100 
3 9FFQ GLU E 37  ? UNP P28472 ? ? 'expression tag'        -17 101 
3 9FFQ PRO E 38  ? UNP P28472 ? ? 'expression tag'        -16 102 
3 9FFQ ASP E 39  ? UNP P28472 ? ? 'expression tag'        -15 103 
3 9FFQ TYR E 40  ? UNP P28472 ? ? 'expression tag'        -14 104 
3 9FFQ ASP E 41  ? UNP P28472 ? ? 'expression tag'        -13 105 
3 9FFQ ILE E 42  ? UNP P28472 ? ? 'expression tag'        -12 106 
3 9FFQ PRO E 43  ? UNP P28472 ? ? 'expression tag'        -11 107 
3 9FFQ THR E 44  ? UNP P28472 ? ? 'expression tag'        -10 108 
3 9FFQ THR E 45  ? UNP P28472 ? ? 'expression tag'        -9  109 
3 9FFQ GLU E 46  ? UNP P28472 ? ? 'expression tag'        -8  110 
3 9FFQ ASN E 47  ? UNP P28472 ? ? 'expression tag'        -7  111 
3 9FFQ LEU E 48  ? UNP P28472 ? ? 'expression tag'        -6  112 
3 9FFQ TYR E 49  ? UNP P28472 ? ? 'expression tag'        -5  113 
3 9FFQ PHE E 50  ? UNP P28472 ? ? 'expression tag'        -4  114 
3 9FFQ GLN E 51  ? UNP P28472 ? ? 'expression tag'        -3  115 
3 9FFQ GLY E 52  ? UNP P28472 ? ? 'expression tag'        -2  116 
3 9FFQ THR E 53  ? UNP P28472 ? ? 'expression tag'        -1  117 
3 9FFQ GLY E 54  ? UNP P28472 ? ? 'expression tag'        0   118 
3 9FFQ SER E 362 ? UNP P28472 ? ? linker                  308 119 
3 9FFQ GLN E 363 ? UNP P28472 ? ? linker                  309 120 
3 9FFQ PRO E 364 ? UNP P28472 ? ? linker                  310 121 
3 9FFQ ALA E 365 ? UNP P28472 ? ? linker                  311 122 
3 9FFQ ARG E 366 ? UNP P28472 ? ? linker                  312 123 
3 9FFQ ALA E 367 ? UNP P28472 ? ? linker                  313 124 
3 9FFQ ALA E 368 ? UNP P28472 ? ? linker                  314 125 
5 9FFQ MET B 1   ? UNP P28472 ? ? 'initiating methionine' -53 126 
5 9FFQ ASP B 2   ? UNP P28472 ? ? 'expression tag'        -52 127 
5 9FFQ GLU B 3   ? UNP P28472 ? ? 'expression tag'        -51 128 
5 9FFQ LYS B 4   ? UNP P28472 ? ? 'expression tag'        -50 129 
5 9FFQ THR B 5   ? UNP P28472 ? ? 'expression tag'        -49 130 
5 9FFQ THR B 6   ? UNP P28472 ? ? 'expression tag'        -48 131 
5 9FFQ GLY B 7   ? UNP P28472 ? ? 'expression tag'        -47 132 
5 9FFQ TRP B 8   ? UNP P28472 ? ? 'expression tag'        -46 133 
5 9FFQ ARG B 9   ? UNP P28472 ? ? 'expression tag'        -45 134 
5 9FFQ GLY B 10  ? UNP P28472 ? ? 'expression tag'        -44 135 
5 9FFQ GLY B 11  ? UNP P28472 ? ? 'expression tag'        -43 136 
5 9FFQ HIS B 12  ? UNP P28472 ? ? 'expression tag'        -42 137 
5 9FFQ VAL B 13  ? UNP P28472 ? ? 'expression tag'        -41 138 
5 9FFQ VAL B 14  ? UNP P28472 ? ? 'expression tag'        -40 139 
5 9FFQ GLU B 15  ? UNP P28472 ? ? 'expression tag'        -39 140 
5 9FFQ GLY B 16  ? UNP P28472 ? ? 'expression tag'        -38 141 
5 9FFQ LEU B 17  ? UNP P28472 ? ? 'expression tag'        -37 142 
5 9FFQ ALA B 18  ? UNP P28472 ? ? 'expression tag'        -36 143 
5 9FFQ GLY B 19  ? UNP P28472 ? ? 'expression tag'        -35 144 
5 9FFQ GLU B 20  ? UNP P28472 ? ? 'expression tag'        -34 145 
5 9FFQ LEU B 21  ? UNP P28472 ? ? 'expression tag'        -33 146 
5 9FFQ GLU B 22  ? UNP P28472 ? ? 'expression tag'        -32 147 
5 9FFQ GLN B 23  ? UNP P28472 ? ? 'expression tag'        -31 148 
5 9FFQ LEU B 24  ? UNP P28472 ? ? 'expression tag'        -30 149 
5 9FFQ ARG B 25  ? UNP P28472 ? ? 'expression tag'        -29 150 
5 9FFQ ALA B 26  ? UNP P28472 ? ? 'expression tag'        -28 151 
5 9FFQ ARG B 27  ? UNP P28472 ? ? 'expression tag'        -27 152 
5 9FFQ LEU B 28  ? UNP P28472 ? ? 'expression tag'        -26 153 
5 9FFQ GLU B 29  ? UNP P28472 ? ? 'expression tag'        -25 154 
5 9FFQ HIS B 30  ? UNP P28472 ? ? 'expression tag'        -24 155 
5 9FFQ HIS B 31  ? UNP P28472 ? ? 'expression tag'        -23 156 
5 9FFQ PRO B 32  ? UNP P28472 ? ? 'expression tag'        -22 157 
5 9FFQ GLN B 33  ? UNP P28472 ? ? 'expression tag'        -21 158 
5 9FFQ GLY B 34  ? UNP P28472 ? ? 'expression tag'        -20 159 
5 9FFQ GLN B 35  ? UNP P28472 ? ? 'expression tag'        -19 160 
5 9FFQ ARG B 36  ? UNP P28472 ? ? 'expression tag'        -18 161 
5 9FFQ GLU B 37  ? UNP P28472 ? ? 'expression tag'        -17 162 
5 9FFQ PRO B 38  ? UNP P28472 ? ? 'expression tag'        -16 163 
5 9FFQ ASP B 39  ? UNP P28472 ? ? 'expression tag'        -15 164 
5 9FFQ TYR B 40  ? UNP P28472 ? ? 'expression tag'        -14 165 
5 9FFQ ASP B 41  ? UNP P28472 ? ? 'expression tag'        -13 166 
5 9FFQ ILE B 42  ? UNP P28472 ? ? 'expression tag'        -12 167 
5 9FFQ PRO B 43  ? UNP P28472 ? ? 'expression tag'        -11 168 
5 9FFQ THR B 44  ? UNP P28472 ? ? 'expression tag'        -10 169 
5 9FFQ THR B 45  ? UNP P28472 ? ? 'expression tag'        -9  170 
5 9FFQ GLU B 46  ? UNP P28472 ? ? 'expression tag'        -8  171 
5 9FFQ ASN B 47  ? UNP P28472 ? ? 'expression tag'        -7  172 
5 9FFQ LEU B 48  ? UNP P28472 ? ? 'expression tag'        -6  173 
5 9FFQ TYR B 49  ? UNP P28472 ? ? 'expression tag'        -5  174 
5 9FFQ PHE B 50  ? UNP P28472 ? ? 'expression tag'        -4  175 
5 9FFQ GLN B 51  ? UNP P28472 ? ? 'expression tag'        -3  176 
5 9FFQ GLY B 52  ? UNP P28472 ? ? 'expression tag'        -2  177 
5 9FFQ THR B 53  ? UNP P28472 ? ? 'expression tag'        -1  178 
5 9FFQ GLY B 54  ? UNP P28472 ? ? 'expression tag'        0   179 
5 9FFQ SER B 362 ? UNP P28472 ? ? linker                  308 180 
5 9FFQ GLN B 363 ? UNP P28472 ? ? linker                  309 181 
5 9FFQ PRO B 364 ? UNP P28472 ? ? linker                  310 182 
5 9FFQ ALA B 365 ? UNP P28472 ? ? linker                  311 183 
5 9FFQ ARG B 366 ? UNP P28472 ? ? linker                  312 184 
5 9FFQ ALA B 367 ? UNP P28472 ? ? linker                  313 185 
5 9FFQ ALA B 368 ? UNP P28472 ? ? linker                  314 186 
7 9FFQ MET A 1   ? UNP P14867 ? ? 'initiating methionine' -52 187 
7 9FFQ ASP A 2   ? UNP P14867 ? ? 'expression tag'        -51 188 
7 9FFQ GLU A 3   ? UNP P14867 ? ? 'expression tag'        -50 189 
7 9FFQ LYS A 4   ? UNP P14867 ? ? 'expression tag'        -49 190 
7 9FFQ THR A 5   ? UNP P14867 ? ? 'expression tag'        -48 191 
7 9FFQ THR A 6   ? UNP P14867 ? ? 'expression tag'        -47 192 
7 9FFQ GLY A 7   ? UNP P14867 ? ? 'expression tag'        -46 193 
7 9FFQ TRP A 8   ? UNP P14867 ? ? 'expression tag'        -45 194 
7 9FFQ ARG A 9   ? UNP P14867 ? ? 'expression tag'        -44 195 
7 9FFQ GLY A 10  ? UNP P14867 ? ? 'expression tag'        -43 196 
7 9FFQ GLY A 11  ? UNP P14867 ? ? 'expression tag'        -42 197 
7 9FFQ HIS A 12  ? UNP P14867 ? ? 'expression tag'        -41 198 
7 9FFQ VAL A 13  ? UNP P14867 ? ? 'expression tag'        -40 199 
7 9FFQ VAL A 14  ? UNP P14867 ? ? 'expression tag'        -39 200 
7 9FFQ GLU A 15  ? UNP P14867 ? ? 'expression tag'        -38 201 
7 9FFQ GLY A 16  ? UNP P14867 ? ? 'expression tag'        -37 202 
7 9FFQ LEU A 17  ? UNP P14867 ? ? 'expression tag'        -36 203 
7 9FFQ ALA A 18  ? UNP P14867 ? ? 'expression tag'        -35 204 
7 9FFQ GLY A 19  ? UNP P14867 ? ? 'expression tag'        -34 205 
7 9FFQ GLU A 20  ? UNP P14867 ? ? 'expression tag'        -33 206 
7 9FFQ LEU A 21  ? UNP P14867 ? ? 'expression tag'        -32 207 
7 9FFQ GLU A 22  ? UNP P14867 ? ? 'expression tag'        -31 208 
7 9FFQ GLN A 23  ? UNP P14867 ? ? 'expression tag'        -30 209 
7 9FFQ LEU A 24  ? UNP P14867 ? ? 'expression tag'        -29 210 
7 9FFQ ARG A 25  ? UNP P14867 ? ? 'expression tag'        -28 211 
7 9FFQ ALA A 26  ? UNP P14867 ? ? 'expression tag'        -27 212 
7 9FFQ ARG A 27  ? UNP P14867 ? ? 'expression tag'        -26 213 
7 9FFQ LEU A 28  ? UNP P14867 ? ? 'expression tag'        -25 214 
7 9FFQ GLU A 29  ? UNP P14867 ? ? 'expression tag'        -24 215 
7 9FFQ HIS A 30  ? UNP P14867 ? ? 'expression tag'        -23 216 
7 9FFQ HIS A 31  ? UNP P14867 ? ? 'expression tag'        -22 217 
7 9FFQ PRO A 32  ? UNP P14867 ? ? 'expression tag'        -21 218 
7 9FFQ GLN A 33  ? UNP P14867 ? ? 'expression tag'        -20 219 
7 9FFQ GLY A 34  ? UNP P14867 ? ? 'expression tag'        -19 220 
7 9FFQ GLN A 35  ? UNP P14867 ? ? 'expression tag'        -18 221 
7 9FFQ ARG A 36  ? UNP P14867 ? ? 'expression tag'        -17 222 
7 9FFQ GLU A 37  ? UNP P14867 ? ? 'expression tag'        -16 223 
7 9FFQ PRO A 38  ? UNP P14867 ? ? 'expression tag'        -15 224 
7 9FFQ ASP A 39  ? UNP P14867 ? ? 'expression tag'        -14 225 
7 9FFQ TYR A 40  ? UNP P14867 ? ? 'expression tag'        -13 226 
7 9FFQ ASP A 41  ? UNP P14867 ? ? 'expression tag'        -12 227 
7 9FFQ ILE A 42  ? UNP P14867 ? ? 'expression tag'        -11 228 
7 9FFQ PRO A 43  ? UNP P14867 ? ? 'expression tag'        -10 229 
7 9FFQ THR A 44  ? UNP P14867 ? ? 'expression tag'        -9  230 
7 9FFQ THR A 45  ? UNP P14867 ? ? 'expression tag'        -8  231 
7 9FFQ GLU A 46  ? UNP P14867 ? ? 'expression tag'        -7  232 
7 9FFQ ASN A 47  ? UNP P14867 ? ? 'expression tag'        -6  233 
7 9FFQ LEU A 48  ? UNP P14867 ? ? 'expression tag'        -5  234 
7 9FFQ TYR A 49  ? UNP P14867 ? ? 'expression tag'        -4  235 
7 9FFQ PHE A 50  ? UNP P14867 ? ? 'expression tag'        -3  236 
7 9FFQ GLN A 51  ? UNP P14867 ? ? 'expression tag'        -2  237 
7 9FFQ GLY A 52  ? UNP P14867 ? ? 'expression tag'        -1  238 
7 9FFQ THR A 53  ? UNP P14867 ? ? 'expression tag'        0   239 
7 9FFQ GLY A 54  ? UNP P14867 ? ? 'expression tag'        1   240 
7 9FFQ GLN A 55  ? UNP P14867 ? ? 'expression tag'        2   241 
7 9FFQ PRO A 56  ? UNP P14867 ? ? 'expression tag'        3   242 
7 9FFQ SER A 57  ? UNP P14867 ? ? 'expression tag'        4   243 
7 9FFQ SER A 366 ? UNP P14867 ? ? linker                  313 244 
7 9FFQ GLN A 367 ? UNP P14867 ? ? linker                  385 245 
7 9FFQ PRO A 368 ? UNP P14867 ? ? linker                  386 246 
7 9FFQ ALA A 369 ? UNP P14867 ? ? linker                  387 247 
7 9FFQ ARG A 370 ? UNP P14867 ? ? linker                  388 248 
7 9FFQ ALA A 371 ? UNP P14867 ? ? linker                  389 249 
7 9FFQ ALA A 372 ? UNP P14867 ? ? linker                  390 250 
9 9FFQ MET C 1   ? UNP P28472 ? ? 'initiating methionine' -53 251 
9 9FFQ ASP C 2   ? UNP P28472 ? ? 'expression tag'        -52 252 
9 9FFQ GLU C 3   ? UNP P28472 ? ? 'expression tag'        -51 253 
9 9FFQ LYS C 4   ? UNP P28472 ? ? 'expression tag'        -50 254 
9 9FFQ THR C 5   ? UNP P28472 ? ? 'expression tag'        -49 255 
9 9FFQ THR C 6   ? UNP P28472 ? ? 'expression tag'        -48 256 
9 9FFQ GLY C 7   ? UNP P28472 ? ? 'expression tag'        -47 257 
9 9FFQ TRP C 8   ? UNP P28472 ? ? 'expression tag'        -46 258 
9 9FFQ ARG C 9   ? UNP P28472 ? ? 'expression tag'        -45 259 
9 9FFQ GLY C 10  ? UNP P28472 ? ? 'expression tag'        -44 260 
9 9FFQ GLY C 11  ? UNP P28472 ? ? 'expression tag'        -43 261 
9 9FFQ HIS C 12  ? UNP P28472 ? ? 'expression tag'        -42 262 
9 9FFQ VAL C 13  ? UNP P28472 ? ? 'expression tag'        -41 263 
9 9FFQ VAL C 14  ? UNP P28472 ? ? 'expression tag'        -40 264 
9 9FFQ GLU C 15  ? UNP P28472 ? ? 'expression tag'        -39 265 
9 9FFQ GLY C 16  ? UNP P28472 ? ? 'expression tag'        -38 266 
9 9FFQ LEU C 17  ? UNP P28472 ? ? 'expression tag'        -37 267 
9 9FFQ ALA C 18  ? UNP P28472 ? ? 'expression tag'        -36 268 
9 9FFQ GLY C 19  ? UNP P28472 ? ? 'expression tag'        -35 269 
9 9FFQ GLU C 20  ? UNP P28472 ? ? 'expression tag'        -34 270 
9 9FFQ LEU C 21  ? UNP P28472 ? ? 'expression tag'        -33 271 
9 9FFQ GLU C 22  ? UNP P28472 ? ? 'expression tag'        -32 272 
9 9FFQ GLN C 23  ? UNP P28472 ? ? 'expression tag'        -31 273 
9 9FFQ LEU C 24  ? UNP P28472 ? ? 'expression tag'        -30 274 
9 9FFQ ARG C 25  ? UNP P28472 ? ? 'expression tag'        -29 275 
9 9FFQ ALA C 26  ? UNP P28472 ? ? 'expression tag'        -28 276 
9 9FFQ ARG C 27  ? UNP P28472 ? ? 'expression tag'        -27 277 
9 9FFQ LEU C 28  ? UNP P28472 ? ? 'expression tag'        -26 278 
9 9FFQ GLU C 29  ? UNP P28472 ? ? 'expression tag'        -25 279 
9 9FFQ HIS C 30  ? UNP P28472 ? ? 'expression tag'        -24 280 
9 9FFQ HIS C 31  ? UNP P28472 ? ? 'expression tag'        -23 281 
9 9FFQ PRO C 32  ? UNP P28472 ? ? 'expression tag'        -22 282 
9 9FFQ GLN C 33  ? UNP P28472 ? ? 'expression tag'        -21 283 
9 9FFQ GLY C 34  ? UNP P28472 ? ? 'expression tag'        -20 284 
9 9FFQ GLN C 35  ? UNP P28472 ? ? 'expression tag'        -19 285 
9 9FFQ ARG C 36  ? UNP P28472 ? ? 'expression tag'        -18 286 
9 9FFQ GLU C 37  ? UNP P28472 ? ? 'expression tag'        -17 287 
9 9FFQ PRO C 38  ? UNP P28472 ? ? 'expression tag'        -16 288 
9 9FFQ ASP C 39  ? UNP P28472 ? ? 'expression tag'        -15 289 
9 9FFQ TYR C 40  ? UNP P28472 ? ? 'expression tag'        -14 290 
9 9FFQ ASP C 41  ? UNP P28472 ? ? 'expression tag'        -13 291 
9 9FFQ ILE C 42  ? UNP P28472 ? ? 'expression tag'        -12 292 
9 9FFQ PRO C 43  ? UNP P28472 ? ? 'expression tag'        -11 293 
9 9FFQ THR C 44  ? UNP P28472 ? ? 'expression tag'        -10 294 
9 9FFQ THR C 45  ? UNP P28472 ? ? 'expression tag'        -9  295 
9 9FFQ GLU C 46  ? UNP P28472 ? ? 'expression tag'        -8  296 
9 9FFQ ASN C 47  ? UNP P28472 ? ? 'expression tag'        -7  297 
9 9FFQ LEU C 48  ? UNP P28472 ? ? 'expression tag'        -6  298 
9 9FFQ TYR C 49  ? UNP P28472 ? ? 'expression tag'        -5  299 
9 9FFQ PHE C 50  ? UNP P28472 ? ? 'expression tag'        -4  300 
9 9FFQ GLN C 51  ? UNP P28472 ? ? 'expression tag'        -3  301 
9 9FFQ GLY C 52  ? UNP P28472 ? ? 'expression tag'        -2  302 
9 9FFQ THR C 53  ? UNP P28472 ? ? 'expression tag'        -1  303 
9 9FFQ GLY C 54  ? UNP P28472 ? ? 'expression tag'        0   304 
9 9FFQ SER C 362 ? UNP P28472 ? ? linker                  308 305 
9 9FFQ GLN C 363 ? UNP P28472 ? ? linker                  309 306 
9 9FFQ PRO C 364 ? UNP P28472 ? ? linker                  310 307 
9 9FFQ ALA C 365 ? UNP P28472 ? ? linker                  311 308 
9 9FFQ ARG C 366 ? UNP P28472 ? ? linker                  312 309 
9 9FFQ ALA C 367 ? UNP P28472 ? ? linker                  313 310 
9 9FFQ ALA C 368 ? UNP P28472 ? ? linker                  314 311 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 65  ? ASP A 77  ? THR D 12  ASP D 24  1 ? 13 
HELX_P HELX_P2  AA2 GLU A 126 ? LYS A 129 ? GLU D 73  LYS D 76  5 ? 4  
HELX_P HELX_P3  AA3 ASN A 140 ? LYS A 146 ? ASN D 87  LYS D 93  5 ? 7  
HELX_P HELX_P4  AA4 GLU A 227 ? ARG A 230 ? GLU D 174 ARG D 177 5 ? 4  
HELX_P HELX_P5  AA5 ILE A 276 ? THR A 283 ? ILE D 223 THR D 230 1 ? 8  
HELX_P HELX_P6  AA6 THR A 283 ? SER A 297 ? THR D 230 SER D 244 1 ? 15 
HELX_P HELX_P7  AA7 PHE A 298 ? LEU A 300 ? PHE D 245 LEU D 247 5 ? 3  
HELX_P HELX_P8  AA8 SER A 304 ? LEU A 330 ? SER D 251 LEU D 277 1 ? 27 
HELX_P HELX_P9  AA9 THR A 337 ? THR A 364 ? THR D 284 THR D 311 1 ? 28 
HELX_P HELX_P10 AB1 GLN A 367 ? ASN A 399 ? GLN D 385 ASN D 417 1 ? 33 
HELX_P HELX_P11 AB2 MET B 63  ? LEU B 74  ? MET E 9   LEU E 20  1 ? 12 
HELX_P HELX_P12 AB3 LYS B 124 ? ALA B 127 ? LYS E 70  ALA E 73  5 ? 4  
HELX_P HELX_P13 AB4 ASP B 138 ? LEU B 145 ? ASP E 84  LEU E 91  5 ? 8  
HELX_P HELX_P14 AB5 GLY B 224 ? LYS B 227 ? GLY E 170 LYS E 173 5 ? 4  
HELX_P HELX_P15 AB6 ILE B 272 ? THR B 279 ? ILE E 218 THR E 225 1 ? 8  
HELX_P HELX_P16 AB7 THR B 279 ? SER B 290 ? THR E 225 SER E 236 1 ? 12 
HELX_P HELX_P17 AB8 TRP B 291 ? ILE B 296 ? TRP E 237 ILE E 242 5 ? 6  
HELX_P HELX_P18 AB9 ALA B 300 ? LEU B 326 ? ALA E 246 LEU E 272 1 ? 27 
HELX_P HELX_P19 AC1 LYS B 333 ? PHE B 360 ? LYS E 279 PHE E 306 1 ? 28 
HELX_P HELX_P20 AC2 GLN B 363 ? TYR B 393 ? GLN E 309 TYR E 446 1 ? 31 
HELX_P HELX_P21 AC3 MET C 63  ? LYS C 75  ? MET B 9   LYS B 21  1 ? 13 
HELX_P HELX_P22 AC4 LYS C 124 ? ALA C 127 ? LYS B 70  ALA B 73  5 ? 4  
HELX_P HELX_P23 AC5 ASP C 138 ? LEU C 145 ? ASP B 84  LEU B 91  5 ? 8  
HELX_P HELX_P24 AC6 GLY C 224 ? LYS C 227 ? GLY B 170 LYS B 173 5 ? 4  
HELX_P HELX_P25 AC7 GLY C 231 ? ILE C 235 ? GLY B 177 ILE B 181 5 ? 5  
HELX_P HELX_P26 AC8 GLY C 273 ? GLN C 278 ? GLY B 219 GLN B 224 1 ? 6  
HELX_P HELX_P27 AC9 TYR C 280 ? SER C 293 ? TYR B 226 SER B 239 1 ? 14 
HELX_P HELX_P28 AD1 PHE C 294 ? ILE C 296 ? PHE B 240 ILE B 242 5 ? 3  
HELX_P HELX_P29 AD2 ALA C 300 ? LEU C 326 ? ALA B 246 LEU B 272 1 ? 27 
HELX_P HELX_P30 AD3 LYS C 333 ? PHE C 360 ? LYS B 279 PHE B 306 1 ? 28 
HELX_P HELX_P31 AD4 GLN C 363 ? TYR C 393 ? GLN B 309 TYR B 446 1 ? 31 
HELX_P HELX_P32 AD5 THR D 66  ? LEU D 76  ? THR A 13  LEU A 23  1 ? 11 
HELX_P HELX_P33 AD6 GLU D 126 ? LYS D 129 ? GLU A 73  LYS A 76  5 ? 4  
HELX_P HELX_P34 AD7 ASN D 140 ? LYS D 146 ? ASN A 87  LYS A 93  5 ? 7  
HELX_P HELX_P35 AD8 GLU D 227 ? ARG D 230 ? GLU A 174 ARG A 177 5 ? 4  
HELX_P HELX_P36 AD9 ILE D 276 ? THR D 283 ? ILE A 223 THR A 230 1 ? 8  
HELX_P HELX_P37 AE1 THR D 283 ? VAL D 296 ? THR A 230 VAL A 243 1 ? 14 
HELX_P HELX_P38 AE2 SER D 297 ? LEU D 300 ? SER A 244 LEU A 247 5 ? 4  
HELX_P HELX_P39 AE3 SER D 304 ? SER D 329 ? SER A 251 SER A 276 1 ? 26 
HELX_P HELX_P40 AE4 THR D 337 ? PHE D 363 ? THR A 284 PHE A 310 1 ? 27 
HELX_P HELX_P41 AE5 GLN D 367 ? LEU D 398 ? GLN A 385 LEU A 416 1 ? 32 
HELX_P HELX_P42 AE6 MET E 63  ? LYS E 75  ? MET C 9   LYS C 21  1 ? 13 
HELX_P HELX_P43 AE7 LYS E 124 ? ALA E 127 ? LYS C 70  ALA C 73  5 ? 4  
HELX_P HELX_P44 AE8 ASP E 138 ? LEU E 145 ? ASP C 84  LEU C 91  5 ? 8  
HELX_P HELX_P45 AE9 GLY E 224 ? LYS E 227 ? GLY C 170 LYS C 173 5 ? 4  
HELX_P HELX_P46 AF1 GLY E 231 ? ILE E 235 ? GLY C 177 ILE C 181 5 ? 5  
HELX_P HELX_P47 AF2 ASN E 271 ? ILE E 276 ? ASN C 217 ILE C 222 1 ? 6  
HELX_P HELX_P48 AF3 THR E 279 ? SER E 293 ? THR C 225 SER C 239 1 ? 15 
HELX_P HELX_P49 AF4 PHE E 294 ? ILE E 296 ? PHE C 240 ILE C 242 5 ? 3  
HELX_P HELX_P50 AF5 ALA E 300 ? LEU E 326 ? ALA C 246 LEU C 272 1 ? 27 
HELX_P HELX_P51 AF6 LYS E 333 ? PHE E 361 ? LYS C 279 PHE C 307 1 ? 29 
HELX_P HELX_P52 AF7 GLN E 363 ? TYR E 393 ? GLN C 309 TYR C 446 1 ? 31 
HELX_P HELX_P53 AF8 LYS F 474 ? THR F 478 ? LYS F 475 THR F 479 5 ? 5  
HELX_P HELX_P54 AF9 TYR F 495 ? THR F 497 ? TYR F 496 THR F 498 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 192 SG  ? ? ? 1_555 A CYS 206 SG ? ? D CYS 139 D CYS 153 1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf2  disulf ?    ? B CYS 190 SG  ? ? ? 1_555 B CYS 204 SG ? ? E CYS 136 E CYS 150 1_555 ? ? ? ? ? ? ? 2.037 ? ?               
disulf3  disulf ?    ? C CYS 190 SG  ? ? ? 1_555 C CYS 204 SG ? ? B CYS 136 B CYS 150 1_555 ? ? ? ? ? ? ? 2.038 ? ?               
disulf4  disulf ?    ? D CYS 192 SG  ? ? ? 1_555 D CYS 206 SG ? ? A CYS 139 A CYS 153 1_555 ? ? ? ? ? ? ? 2.037 ? ?               
disulf5  disulf ?    ? E CYS 190 SG  ? ? ? 1_555 E CYS 204 SG ? ? C CYS 136 C CYS 150 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf6  disulf ?    ? F CYS 409 SG  ? ? ? 1_555 F CYS 483 SG ? ? F CYS 410 F CYS 484 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
covale1  covale one  ? A ASN 164 ND2 ? ? ? 1_555 G NAG .   C1 ? ? D ASN 111 a NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale2  covale one  ? B ASN 134 ND2 ? ? ? 1_555 I NAG .   C1 ? ? E ASN 80  G NAG 1   1_555 ? ? ? ? ? ? ? 1.437 ? N-Glycosylation 
covale3  covale one  ? B ASN 203 ND2 ? ? ? 1_555 H NAG .   C1 ? ? E ASN 149 b NAG 1   1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale4  covale one  ? C ASN 134 ND2 ? ? ? 1_555 K NAG .   C1 ? ? B ASN 80  H NAG 1   1_555 ? ? ? ? ? ? ? 1.437 ? N-Glycosylation 
covale5  covale one  ? C ASN 203 ND2 ? ? ? 1_555 J NAG .   C1 ? ? B ASN 149 c NAG 1   1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale6  covale one  ? D ASN 164 ND2 ? ? ? 1_555 L NAG .   C1 ? ? A ASN 111 d NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale7  covale one  ? E ASN 134 ND2 ? ? ? 1_555 N NAG .   C1 ? ? C ASN 80  I NAG 1   1_555 ? ? ? ? ? ? ? 1.452 ? N-Glycosylation 
covale8  covale one  ? E ASN 203 ND2 ? ? ? 1_555 M NAG .   C1 ? ? C ASN 149 e NAG 1   1_555 ? ? ? ? ? ? ? 1.438 ? N-Glycosylation 
covale9  covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? a NAG 1   a NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale10 covale both ? G NAG .   O4  ? ? ? 1_555 G BMA .   C1 ? ? a NAG 2   a BMA 3   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale11 covale both ? G BMA .   O3  ? ? ? 1_555 G MAN .   C1 ? ? a BMA 3   a MAN 4   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale12 covale both ? G BMA .   O6  ? ? ? 1_555 G MAN .   C1 ? ? a BMA 3   a MAN 5   1_555 ? ? ? ? ? ? ? 1.446 ? ?               
covale13 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? b NAG 1   b NAG 2   1_555 ? ? ? ? ? ? ? 1.430 ? ?               
covale14 covale both ? H NAG .   O4  ? ? ? 1_555 H BMA .   C1 ? ? b NAG 2   b BMA 3   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
covale15 covale both ? H BMA .   O3  ? ? ? 1_555 H MAN .   C1 ? ? b BMA 3   b MAN 4   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale16 covale both ? H BMA .   O6  ? ? ? 1_555 H MAN .   C1 ? ? b BMA 3   b MAN 5   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale17 covale both ? I NAG .   O4  ? ? ? 1_555 I NAG .   C1 ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale18 covale both ? J NAG .   O4  ? ? ? 1_555 J NAG .   C1 ? ? c NAG 1   c NAG 2   1_555 ? ? ? ? ? ? ? 1.436 ? ?               
covale19 covale both ? J NAG .   O4  ? ? ? 1_555 J BMA .   C1 ? ? c NAG 2   c BMA 3   1_555 ? ? ? ? ? ? ? 1.434 ? ?               
covale20 covale both ? J BMA .   O3  ? ? ? 1_555 J MAN .   C1 ? ? c BMA 3   c MAN 4   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale21 covale both ? J BMA .   O6  ? ? ? 1_555 J MAN .   C1 ? ? c BMA 3   c MAN 5   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale22 covale both ? K NAG .   O4  ? ? ? 1_555 K NAG .   C1 ? ? H NAG 1   H NAG 2   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale23 covale both ? L NAG .   O4  ? ? ? 1_555 L NAG .   C1 ? ? d NAG 1   d NAG 2   1_555 ? ? ? ? ? ? ? 1.456 ? ?               
covale24 covale both ? L NAG .   O4  ? ? ? 1_555 L BMA .   C1 ? ? d NAG 2   d BMA 3   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale25 covale both ? L BMA .   O3  ? ? ? 1_555 L MAN .   C1 ? ? d BMA 3   d MAN 4   1_555 ? ? ? ? ? ? ? 1.432 ? ?               
covale26 covale both ? L BMA .   O6  ? ? ? 1_555 L MAN .   C1 ? ? d BMA 3   d MAN 5   1_555 ? ? ? ? ? ? ? 1.436 ? ?               
covale27 covale both ? M NAG .   O4  ? ? ? 1_555 M NAG .   C1 ? ? e NAG 1   e NAG 2   1_555 ? ? ? ? ? ? ? 1.434 ? ?               
covale28 covale both ? M NAG .   O4  ? ? ? 1_555 M BMA .   C1 ? ? e NAG 2   e BMA 3   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale29 covale both ? M BMA .   O3  ? ? ? 1_555 M MAN .   C1 ? ? e BMA 3   e MAN 4   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale30 covale both ? M BMA .   O6  ? ? ? 1_555 M MAN .   C1 ? ? e BMA 3   e MAN 5   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale31 covale both ? N NAG .   O4  ? ? ? 1_555 N NAG .   C1 ? ? I NAG 1   I NAG 2   1_555 ? ? ? ? ? ? ? 1.446 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG G .   ? ASN A 164 ? NAG a 1   ? 1_555 ASN D 111 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG H .   ? ASN B 203 ? NAG b 1   ? 1_555 ASN E 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG I .   ? ASN B 134 ? NAG G 1   ? 1_555 ASN E 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG J .   ? ASN C 203 ? NAG c 1   ? 1_555 ASN B 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG K .   ? ASN C 134 ? NAG H 1   ? 1_555 ASN B 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG L .   ? ASN D 164 ? NAG d 1   ? 1_555 ASN A 111 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG M .   ? ASN E 203 ? NAG e 1   ? 1_555 ASN C 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG N .   ? ASN E 134 ? NAG I 1   ? 1_555 ASN C 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  CYS A 192 ? CYS A 206 ? CYS D 139 ? 1_555 CYS D 153 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS B 190 ? CYS B 204 ? CYS E 136 ? 1_555 CYS E 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS C 190 ? CYS C 204 ? CYS B 136 ? 1_555 CYS B 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS D 192 ? CYS D 206 ? CYS A 139 ? 1_555 CYS A 153 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS E 190 ? CYS E 204 ? CYS C 136 ? 1_555 CYS C 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
14 CYS F 409 ? CYS F 483 ? CYS F 410 ? 1_555 CYS F 484 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1  MET 165 A . ? MET 112 D THR 166 A ? THR 113 D 1 -1.92 
2  PHE 199 A . ? PHE 146 D PRO 200 A ? PRO 147 D 1 -0.98 
3  VAL 163 B . ? VAL 109 E THR 164 B ? THR 110 E 1 3.17  
4  TYR 197 B . ? TYR 143 E PRO 198 B ? PRO 144 E 1 -0.42 
5  VAL 163 C . ? VAL 109 B THR 164 C ? THR 110 B 1 1.04  
6  TYR 197 C . ? TYR 143 B PRO 198 C ? PRO 144 B 1 3.49  
7  MET 165 D . ? MET 112 A THR 166 D ? THR 113 A 1 -1.13 
8  PHE 199 D . ? PHE 146 A PRO 200 D ? PRO 147 A 1 -1.36 
9  VAL 163 E . ? VAL 109 C THR 164 E ? THR 110 C 1 3.85  
10 TYR 197 E . ? TYR 143 C PRO 198 E ? PRO 144 C 1 0.69  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 5 ? 
AA3 ? 4 ? 
AA4 ? 6 ? 
AA5 ? 5 ? 
AA6 ? 4 ? 
AA7 ? 6 ? 
AA8 ? 5 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 5 ? 
AB3 ? 4 ? 
AB4 ? 6 ? 
AB5 ? 5 ? 
AB6 ? 4 ? 
AB7 ? 4 ? 
AB8 ? 5 ? 
AB9 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? parallel      
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA7 5 6 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? parallel      
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? parallel      
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? parallel      
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? parallel      
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB8 4 5 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AB9 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 136 ? LEU A 139 ? VAL D 83  LEU D 86  
AA1 2 LYS A 170 ? THR A 175 ? LYS D 117 THR D 122 
AA1 3 THR A 179 ? GLU A 191 ? THR D 126 GLU D 138 
AA1 4 GLU A 112 ? LYS A 124 ? GLU D 59  LYS D 71  
AA1 5 THR A 92  ? SER A 107 ? THR D 39  SER D 54  
AA1 6 VAL A 220 ? TRP A 224 ? VAL D 167 TRP D 171 
AA2 1 VAL A 161 ? ALA A 162 ? VAL D 108 ALA D 109 
AA2 2 THR A 179 ? GLU A 191 ? THR D 126 GLU D 138 
AA2 3 GLU A 112 ? LYS A 124 ? GLU D 59  LYS D 71  
AA2 4 THR A 92  ? SER A 107 ? THR D 39  SER D 54  
AA2 5 VAL A 232 ? VAL A 234 ? VAL D 179 VAL D 181 
AA3 1 THR A 152 ? PHE A 154 ? THR D 99  PHE D 101 
AA3 2 ALA A 203 ? SER A 212 ? ALA D 150 SER D 159 
AA3 3 GLY A 261 ? ARG A 274 ? GLY D 208 ARG D 221 
AA3 4 TYR A 244 ? SER A 258 ? TYR D 191 SER D 205 
AA4 1 THR B 136 ? LEU B 137 ? THR E 82  LEU E 83  
AA4 2 ARG B 168 ? LEU B 172 ? ARG E 114 LEU E 118 
AA4 3 THR B 177 ? ALA B 189 ? THR E 123 ALA E 135 
AA4 4 ASP B 110 ? ARG B 122 ? ASP E 56  ARG E 68  
AA4 5 VAL B 90  ? SER B 105 ? VAL E 36  SER E 51  
AA4 6 ILE B 218 ? TRP B 222 ? ILE E 164 TRP E 168 
AA5 1 ASP B 155 ? VAL B 160 ? ASP E 101 VAL E 106 
AA5 2 THR B 177 ? ALA B 189 ? THR E 123 ALA E 135 
AA5 3 ASP B 110 ? ARG B 122 ? ASP E 56  ARG E 68  
AA5 4 VAL B 90  ? SER B 105 ? VAL E 36  SER E 51  
AA5 5 VAL B 229 ? THR B 230 ? VAL E 175 THR E 176 
AA6 1 THR B 150 ? PHE B 152 ? THR E 96  PHE E 98  
AA6 2 GLU B 201 ? SER B 210 ? GLU E 147 SER E 156 
AA6 3 GLY B 257 ? ARG B 270 ? GLY E 203 ARG E 216 
AA6 4 PHE B 240 ? PHE B 254 ? PHE E 186 PHE E 200 
AA7 1 LEU C 135 ? LEU C 137 ? LEU B 81  LEU B 83  
AA7 2 ARG C 168 ? LEU C 172 ? ARG B 114 LEU B 118 
AA7 3 THR C 177 ? ALA C 189 ? THR B 123 ALA B 135 
AA7 4 ASP C 110 ? ARG C 122 ? ASP B 56  ARG B 68  
AA7 5 VAL C 90  ? SER C 105 ? VAL B 36  SER B 51  
AA7 6 ILE C 218 ? TRP C 222 ? ILE B 164 TRP B 168 
AA8 1 ASP C 155 ? VAL C 160 ? ASP B 101 VAL B 106 
AA8 2 THR C 177 ? ALA C 189 ? THR B 123 ALA B 135 
AA8 3 ASP C 110 ? ARG C 122 ? ASP B 56  ARG B 68  
AA8 4 VAL C 90  ? SER C 105 ? VAL B 36  SER B 51  
AA8 5 VAL C 229 ? THR C 230 ? VAL B 175 THR B 176 
AA9 1 THR C 150 ? PHE C 152 ? THR B 96  PHE B 98  
AA9 2 GLU C 201 ? SER C 210 ? GLU B 147 SER B 156 
AA9 3 GLY C 257 ? ARG C 270 ? GLY B 203 ARG B 216 
AA9 4 PHE C 240 ? PHE C 254 ? PHE B 186 PHE B 200 
AB1 1 VAL D 136 ? LEU D 139 ? VAL A 83  LEU A 86  
AB1 2 LYS D 170 ? THR D 175 ? LYS A 117 THR A 122 
AB1 3 THR D 179 ? GLU D 191 ? THR A 126 GLU A 138 
AB1 4 GLU D 112 ? LYS D 124 ? GLU A 59  LYS A 71  
AB1 5 THR D 92  ? SER D 107 ? THR A 39  SER A 54  
AB1 6 VAL D 220 ? TRP D 224 ? VAL A 167 TRP A 171 
AB2 1 VAL D 161 ? ALA D 162 ? VAL A 108 ALA A 109 
AB2 2 THR D 179 ? GLU D 191 ? THR A 126 GLU A 138 
AB2 3 GLU D 112 ? LYS D 124 ? GLU A 59  LYS A 71  
AB2 4 THR D 92  ? SER D 107 ? THR A 39  SER A 54  
AB2 5 VAL D 232 ? VAL D 234 ? VAL A 179 VAL A 181 
AB3 1 THR D 152 ? PHE D 154 ? THR A 99  PHE A 101 
AB3 2 ALA D 203 ? SER D 212 ? ALA A 150 SER A 159 
AB3 3 GLY D 261 ? ARG D 274 ? GLY A 208 ARG A 221 
AB3 4 TYR D 244 ? SER D 258 ? TYR A 191 SER A 205 
AB4 1 LEU E 135 ? LEU E 137 ? LEU C 81  LEU C 83  
AB4 2 ARG E 168 ? LEU E 172 ? ARG C 114 LEU C 118 
AB4 3 THR E 177 ? ALA E 189 ? THR C 123 ALA C 135 
AB4 4 ASP E 110 ? ARG E 122 ? ASP C 56  ARG C 68  
AB4 5 VAL E 90  ? ILE E 101 ? VAL C 36  ILE C 47  
AB4 6 ILE E 218 ? TRP E 222 ? ILE C 164 TRP C 168 
AB5 1 ASP E 155 ? VAL E 160 ? ASP C 101 VAL C 106 
AB5 2 THR E 177 ? ALA E 189 ? THR C 123 ALA C 135 
AB5 3 ASP E 110 ? ARG E 122 ? ASP C 56  ARG C 68  
AB5 4 VAL E 90  ? ILE E 101 ? VAL C 36  ILE C 47  
AB5 5 VAL E 229 ? THR E 230 ? VAL C 175 THR C 176 
AB6 1 THR E 150 ? PHE E 152 ? THR C 96  PHE C 98  
AB6 2 GLU E 201 ? SER E 210 ? GLU C 147 SER C 156 
AB6 3 GLY E 257 ? ARG E 270 ? GLY C 203 ARG C 216 
AB6 4 PHE E 240 ? PHE E 254 ? PHE C 186 PHE C 200 
AB7 1 VAL F 2   ? SER F 7   ? VAL F 3   SER F 8   
AB7 2 ARG F 406 ? GLY F 413 ? ARG F 407 GLY F 414 
AB7 3 THR F 465 ? GLU F 469 ? THR F 466 GLU F 470 
AB7 4 THR F 456 ? ASP F 460 ? THR F 457 ASP F 461 
AB8 1 THR F 445 ? TYR F 447 ? THR F 446 TYR F 448 
AB8 2 ARG F 432 ? SER F 439 ? ARG F 433 SER F 440 
AB8 3 ILE F 420 ? GLN F 426 ? ILE F 421 GLN F 427 
AB8 4 ALA F 479 ? LYS F 486 ? ALA F 480 LYS F 487 
AB8 5 TYR F 499 ? TRP F 502 ? TYR F 500 TRP F 503 
AB9 1 THR F 445 ? TYR F 447 ? THR F 446 TYR F 448 
AB9 2 ARG F 432 ? SER F 439 ? ARG F 433 SER F 440 
AB9 3 ILE F 420 ? GLN F 426 ? ILE F 421 GLN F 427 
AB9 4 ALA F 479 ? LYS F 486 ? ALA F 480 LYS F 487 
AB9 5 THR F 506 ? VAL F 508 ? THR F 507 VAL F 509 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 137 ? N LEU D 84  O ILE A 174 ? O ILE D 121 
AA1 2 3 N THR A 175 ? N THR D 122 O THR A 179 ? O THR D 126 
AA1 3 4 O VAL A 188 ? O VAL D 135 N ILE A 115 ? N ILE D 62  
AA1 4 5 O GLU A 112 ? O GLU D 59  N SER A 107 ? N SER D 54  
AA1 5 6 N THR A 96  ? N THR D 43  O GLU A 223 ? O GLU D 170 
AA2 1 2 N VAL A 161 ? N VAL D 108 O THR A 187 ? O THR D 134 
AA2 2 3 O VAL A 188 ? O VAL D 135 N ILE A 115 ? N ILE D 62  
AA2 3 4 O GLU A 112 ? O GLU D 59  N SER A 107 ? N SER D 54  
AA2 4 5 N ILE A 98  ? N ILE D 45  O VAL A 233 ? O VAL D 180 
AA3 1 2 N PHE A 153 ? N PHE D 100 O GLY A 211 ? O GLY D 158 
AA3 2 3 N PHE A 210 ? N PHE D 157 O MET A 266 ? O MET D 213 
AA3 3 4 O HIS A 271 ? O HIS D 218 N LEU A 247 ? N LEU D 194 
AA4 1 2 N LEU B 137 ? N LEU E 83  O ILE B 170 ? O ILE E 116 
AA4 2 3 N ARG B 171 ? N ARG E 117 O LEU B 179 ? O LEU E 125 
AA4 3 4 O VAL B 178 ? O VAL E 124 N TRP B 121 ? N TRP E 67  
AA4 4 5 O GLN B 118 ? O GLN E 64  N ASN B 95  ? N ASN E 41  
AA4 5 6 N VAL B 92  ? N VAL E 38  O GLU B 219 ? O GLU E 165 
AA5 1 2 N LYS B 157 ? N LYS E 103 O THR B 187 ? O THR E 133 
AA5 2 3 O VAL B 178 ? O VAL E 124 N TRP B 121 ? N TRP E 67  
AA5 3 4 O GLN B 118 ? O GLN E 64  N ASN B 95  ? N ASN E 41  
AA5 4 5 N ILE B 98  ? N ILE E 44  O THR B 230 ? O THR E 176 
AA6 1 2 N TYR B 151 ? N TYR E 97  O GLU B 209 ? O GLU E 155 
AA6 2 3 N ILE B 208 ? N ILE E 154 O LEU B 262 ? O LEU E 208 
AA6 3 4 O GLY B 257 ? O GLY E 203 N PHE B 254 ? N PHE E 200 
AA7 1 2 N LEU C 135 ? N LEU B 81  O LEU C 172 ? O LEU B 118 
AA7 2 3 N ARG C 171 ? N ARG B 117 O LEU C 179 ? O LEU B 125 
AA7 3 4 O THR C 186 ? O THR B 132 N LEU C 113 ? N LEU B 59  
AA7 4 5 O GLN C 118 ? O GLN B 64  N ASN C 95  ? N ASN B 41  
AA7 5 6 N VAL C 92  ? N VAL B 38  O GLU C 219 ? O GLU B 165 
AA8 1 2 N LYS C 156 ? N LYS B 102 O THR C 187 ? O THR B 133 
AA8 2 3 O THR C 186 ? O THR B 132 N LEU C 113 ? N LEU B 59  
AA8 3 4 O GLN C 118 ? O GLN B 64  N ASN C 95  ? N ASN B 41  
AA8 4 5 N ILE C 98  ? N ILE B 44  O THR C 230 ? O THR B 176 
AA9 1 2 N TYR C 151 ? N TYR B 97  O GLU C 209 ? O GLU B 155 
AA9 2 3 N ILE C 208 ? N ILE B 154 O LEU C 262 ? O LEU B 208 
AA9 3 4 O ARG C 267 ? O ARG B 213 N VAL C 243 ? N VAL B 189 
AB1 1 2 N LEU D 137 ? N LEU A 84  O ILE D 174 ? O ILE A 121 
AB1 2 3 N THR D 175 ? N THR A 122 O THR D 179 ? O THR A 126 
AB1 3 4 O TYR D 182 ? O TYR A 129 N GLN D 121 ? N GLN A 68  
AB1 4 5 O ARG D 120 ? O ARG A 67  N ASP D 97  ? N ASP A 44  
AB1 5 6 N VAL D 94  ? N VAL A 41  O GLU D 223 ? O GLU A 170 
AB2 1 2 N VAL D 161 ? N VAL A 108 O THR D 187 ? O THR A 134 
AB2 2 3 O TYR D 182 ? O TYR A 129 N GLN D 121 ? N GLN A 68  
AB2 3 4 O ARG D 120 ? O ARG A 67  N ASP D 97  ? N ASP A 44  
AB2 4 5 N ILE D 98  ? N ILE A 45  O VAL D 233 ? O VAL A 180 
AB3 1 2 N PHE D 153 ? N PHE A 100 O GLY D 211 ? O GLY A 158 
AB3 2 3 N HIS D 204 ? N HIS A 151 O LEU D 272 ? O LEU A 219 
AB3 3 4 O GLY D 261 ? O GLY A 208 N SER D 258 ? N SER A 205 
AB4 1 2 N LEU E 135 ? N LEU C 81  O LEU E 172 ? O LEU C 118 
AB4 2 3 N ARG E 171 ? N ARG C 117 O LEU E 179 ? O LEU C 125 
AB4 3 4 O THR E 186 ? O THR C 132 N LEU E 113 ? N LEU C 59  
AB4 4 5 O THR E 114 ? O THR C 60  N ALA E 99  ? N ALA C 45  
AB4 5 6 N VAL E 92  ? N VAL C 38  O GLU E 219 ? O GLU C 165 
AB5 1 2 N LYS E 156 ? N LYS C 102 O THR E 187 ? O THR C 133 
AB5 2 3 O THR E 186 ? O THR C 132 N LEU E 113 ? N LEU C 59  
AB5 3 4 O THR E 114 ? O THR C 60  N ALA E 99  ? N ALA C 45  
AB5 4 5 N ILE E 98  ? N ILE C 44  O THR E 230 ? O THR C 176 
AB6 1 2 N TYR E 151 ? N TYR C 97  O GLU E 209 ? O GLU C 155 
AB6 2 3 N ILE E 208 ? N ILE C 154 O LEU E 262 ? O LEU C 208 
AB6 3 4 O TYR E 259 ? O TYR C 205 N VAL E 252 ? N VAL C 198 
AB7 1 2 N SER F 7   ? N SER F 8   O SER F 408 ? O SER F 409 
AB7 2 3 N LEU F 407 ? N LEU F 408 O LEU F 468 ? O LEU F 469 
AB7 3 4 O TYR F 467 ? O TYR F 468 N SER F 458 ? N SER F 459 
AB8 1 2 O SER F 446 ? O SER F 447 N ALA F 437 ? N ALA F 438 
AB8 2 3 O GLY F 436 ? O GLY F 437 N TRP F 423 ? N TRP F 424 
AB8 3 4 N GLY F 422 ? N GLY F 423 O ALA F 484 ? O ALA F 485 
AB8 4 5 N ALA F 485 ? N ALA F 486 O TYR F 501 ? O TYR F 502 
AB9 1 2 O SER F 446 ? O SER F 447 N ALA F 437 ? N ALA F 438 
AB9 2 3 O GLY F 436 ? O GLY F 437 N TRP F 423 ? N TRP F 424 
AB9 3 4 N GLY F 422 ? N GLY F 423 O ALA F 484 ? O ALA F 485 
AB9 4 5 N TYR F 481 ? N TYR F 482 O THR F 506 ? O THR F 507 
# 
_pdbx_entry_details.entry_id                   9FFQ 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS D 106 ? ? -160.41 101.54  
2  1 MET D 148 ? ? -98.35  32.23   
3  1 ARG D 173 ? ? -118.43 -165.14 
4  1 LYS D 312 ? ? 72.45   -5.09   
5  1 ASP E 95  ? ? -90.76  56.47   
6  1 PRO E 144 ? ? -92.51  30.62   
7  1 PRO B 78  ? ? -82.92  49.72   
8  1 ASP B 95  ? ? -87.53  49.69   
9  1 LYS B 103 ? ? -161.70 115.45  
10 1 PRO B 144 ? ? -96.93  35.02   
11 1 LYS A 105 ? ? -100.66 -60.11  
12 1 ARG A 173 ? ? -140.97 -159.00 
13 1 LYS C 103 ? ? -161.09 116.36  
14 1 LEU C 223 ? ? 73.39   -1.44   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9FFQ 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   'FSC at 0.5' 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   30 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      OTHER 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  6HUK 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                6HUK 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    9FFQ 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.1 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               64000 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '137 mM NaCl, 2.7 mM KCl, 4.3 mM Na2HPO' 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
;Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric desensitised state of branch 1
;
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2,3 
# 
_em_image_scans.entry_id                9FFQ 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        4096 
_em_image_scans.dimension_width         4096 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9FFQ 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1400 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           96000 
_em_imaging.calibrated_magnification        96000 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          'current: 30mA' 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9FFQ 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   281 
_em_vitrification.instrument            'HOMEMADE PLUNGER' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9FFQ 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9FFQ 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 D MET -52 ? A MET 1   
2   1 Y 1 D ASP -51 ? A ASP 2   
3   1 Y 1 D GLU -50 ? A GLU 3   
4   1 Y 1 D LYS -49 ? A LYS 4   
5   1 Y 1 D THR -48 ? A THR 5   
6   1 Y 1 D THR -47 ? A THR 6   
7   1 Y 1 D GLY -46 ? A GLY 7   
8   1 Y 1 D TRP -45 ? A TRP 8   
9   1 Y 1 D ARG -44 ? A ARG 9   
10  1 Y 1 D GLY -43 ? A GLY 10  
11  1 Y 1 D GLY -42 ? A GLY 11  
12  1 Y 1 D HIS -41 ? A HIS 12  
13  1 Y 1 D VAL -40 ? A VAL 13  
14  1 Y 1 D VAL -39 ? A VAL 14  
15  1 Y 1 D GLU -38 ? A GLU 15  
16  1 Y 1 D GLY -37 ? A GLY 16  
17  1 Y 1 D LEU -36 ? A LEU 17  
18  1 Y 1 D ALA -35 ? A ALA 18  
19  1 Y 1 D GLY -34 ? A GLY 19  
20  1 Y 1 D GLU -33 ? A GLU 20  
21  1 Y 1 D LEU -32 ? A LEU 21  
22  1 Y 1 D GLU -31 ? A GLU 22  
23  1 Y 1 D GLN -30 ? A GLN 23  
24  1 Y 1 D LEU -29 ? A LEU 24  
25  1 Y 1 D ARG -28 ? A ARG 25  
26  1 Y 1 D ALA -27 ? A ALA 26  
27  1 Y 1 D ARG -26 ? A ARG 27  
28  1 Y 1 D LEU -25 ? A LEU 28  
29  1 Y 1 D GLU -24 ? A GLU 29  
30  1 Y 1 D HIS -23 ? A HIS 30  
31  1 Y 1 D HIS -22 ? A HIS 31  
32  1 Y 1 D PRO -21 ? A PRO 32  
33  1 Y 1 D GLN -20 ? A GLN 33  
34  1 Y 1 D GLY -19 ? A GLY 34  
35  1 Y 1 D GLN -18 ? A GLN 35  
36  1 Y 1 D ARG -17 ? A ARG 36  
37  1 Y 1 D GLU -16 ? A GLU 37  
38  1 Y 1 D PRO -15 ? A PRO 38  
39  1 Y 1 D ASP -14 ? A ASP 39  
40  1 Y 1 D TYR -13 ? A TYR 40  
41  1 Y 1 D ASP -12 ? A ASP 41  
42  1 Y 1 D ILE -11 ? A ILE 42  
43  1 Y 1 D PRO -10 ? A PRO 43  
44  1 Y 1 D THR -9  ? A THR 44  
45  1 Y 1 D THR -8  ? A THR 45  
46  1 Y 1 D GLU -7  ? A GLU 46  
47  1 Y 1 D ASN -6  ? A ASN 47  
48  1 Y 1 D LEU -5  ? A LEU 48  
49  1 Y 1 D TYR -4  ? A TYR 49  
50  1 Y 1 D PHE -3  ? A PHE 50  
51  1 Y 1 D GLN -2  ? A GLN 51  
52  1 Y 1 D GLY -1  ? A GLY 52  
53  1 Y 1 D THR 0   ? A THR 53  
54  1 Y 1 D GLY 1   ? A GLY 54  
55  1 Y 1 D GLN 2   ? A GLN 55  
56  1 Y 1 D PRO 3   ? A PRO 56  
57  1 Y 1 D SER 4   ? A SER 57  
58  1 Y 1 D GLN 5   ? A GLN 58  
59  1 Y 1 D ASP 6   ? A ASP 59  
60  1 Y 1 D GLU 7   ? A GLU 60  
61  1 Y 1 D LEU 8   ? A LEU 61  
62  1 Y 1 D LYS 9   ? A LYS 62  
63  1 Y 1 D ASP 10  ? A ASP 63  
64  1 Y 1 D ASN 11  ? A ASN 64  
65  1 Y 1 D GLU 419 ? A GLU 401 
66  1 Y 1 D PRO 420 ? A PRO 402 
67  1 Y 1 D GLN 421 ? A GLN 403 
68  1 Y 1 D LEU 422 ? A LEU 404 
69  1 Y 1 D LYS 423 ? A LYS 405 
70  1 Y 1 D ALA 424 ? A ALA 406 
71  1 Y 1 D PRO 425 ? A PRO 407 
72  1 Y 1 D THR 426 ? A THR 408 
73  1 Y 1 D PRO 427 ? A PRO 409 
74  1 Y 1 D HIS 428 ? A HIS 410 
75  1 Y 1 D GLN 429 ? A GLN 411 
76  1 Y 1 E MET -53 ? B MET 1   
77  1 Y 1 E ASP -52 ? B ASP 2   
78  1 Y 1 E GLU -51 ? B GLU 3   
79  1 Y 1 E LYS -50 ? B LYS 4   
80  1 Y 1 E THR -49 ? B THR 5   
81  1 Y 1 E THR -48 ? B THR 6   
82  1 Y 1 E GLY -47 ? B GLY 7   
83  1 Y 1 E TRP -46 ? B TRP 8   
84  1 Y 1 E ARG -45 ? B ARG 9   
85  1 Y 1 E GLY -44 ? B GLY 10  
86  1 Y 1 E GLY -43 ? B GLY 11  
87  1 Y 1 E HIS -42 ? B HIS 12  
88  1 Y 1 E VAL -41 ? B VAL 13  
89  1 Y 1 E VAL -40 ? B VAL 14  
90  1 Y 1 E GLU -39 ? B GLU 15  
91  1 Y 1 E GLY -38 ? B GLY 16  
92  1 Y 1 E LEU -37 ? B LEU 17  
93  1 Y 1 E ALA -36 ? B ALA 18  
94  1 Y 1 E GLY -35 ? B GLY 19  
95  1 Y 1 E GLU -34 ? B GLU 20  
96  1 Y 1 E LEU -33 ? B LEU 21  
97  1 Y 1 E GLU -32 ? B GLU 22  
98  1 Y 1 E GLN -31 ? B GLN 23  
99  1 Y 1 E LEU -30 ? B LEU 24  
100 1 Y 1 E ARG -29 ? B ARG 25  
101 1 Y 1 E ALA -28 ? B ALA 26  
102 1 Y 1 E ARG -27 ? B ARG 27  
103 1 Y 1 E LEU -26 ? B LEU 28  
104 1 Y 1 E GLU -25 ? B GLU 29  
105 1 Y 1 E HIS -24 ? B HIS 30  
106 1 Y 1 E HIS -23 ? B HIS 31  
107 1 Y 1 E PRO -22 ? B PRO 32  
108 1 Y 1 E GLN -21 ? B GLN 33  
109 1 Y 1 E GLY -20 ? B GLY 34  
110 1 Y 1 E GLN -19 ? B GLN 35  
111 1 Y 1 E ARG -18 ? B ARG 36  
112 1 Y 1 E GLU -17 ? B GLU 37  
113 1 Y 1 E PRO -16 ? B PRO 38  
114 1 Y 1 E ASP -15 ? B ASP 39  
115 1 Y 1 E TYR -14 ? B TYR 40  
116 1 Y 1 E ASP -13 ? B ASP 41  
117 1 Y 1 E ILE -12 ? B ILE 42  
118 1 Y 1 E PRO -11 ? B PRO 43  
119 1 Y 1 E THR -10 ? B THR 44  
120 1 Y 1 E THR -9  ? B THR 45  
121 1 Y 1 E GLU -8  ? B GLU 46  
122 1 Y 1 E ASN -7  ? B ASN 47  
123 1 Y 1 E LEU -6  ? B LEU 48  
124 1 Y 1 E TYR -5  ? B TYR 49  
125 1 Y 1 E PHE -4  ? B PHE 50  
126 1 Y 1 E GLN -3  ? B GLN 51  
127 1 Y 1 E GLY -2  ? B GLY 52  
128 1 Y 1 E THR -1  ? B THR 53  
129 1 Y 1 E GLY 0   ? B GLY 54  
130 1 Y 1 E GLN 1   ? B GLN 55  
131 1 Y 1 E SER 2   ? B SER 56  
132 1 Y 1 E VAL 3   ? B VAL 57  
133 1 Y 1 E ASN 4   ? B ASN 58  
134 1 Y 1 E ASP 5   ? B ASP 59  
135 1 Y 1 E PRO 6   ? B PRO 60  
136 1 Y 1 E GLY 7   ? B GLY 61  
137 1 Y 1 E ASN 448 ? B ASN 395 
138 1 Y 1 B MET -53 ? C MET 1   
139 1 Y 1 B ASP -52 ? C ASP 2   
140 1 Y 1 B GLU -51 ? C GLU 3   
141 1 Y 1 B LYS -50 ? C LYS 4   
142 1 Y 1 B THR -49 ? C THR 5   
143 1 Y 1 B THR -48 ? C THR 6   
144 1 Y 1 B GLY -47 ? C GLY 7   
145 1 Y 1 B TRP -46 ? C TRP 8   
146 1 Y 1 B ARG -45 ? C ARG 9   
147 1 Y 1 B GLY -44 ? C GLY 10  
148 1 Y 1 B GLY -43 ? C GLY 11  
149 1 Y 1 B HIS -42 ? C HIS 12  
150 1 Y 1 B VAL -41 ? C VAL 13  
151 1 Y 1 B VAL -40 ? C VAL 14  
152 1 Y 1 B GLU -39 ? C GLU 15  
153 1 Y 1 B GLY -38 ? C GLY 16  
154 1 Y 1 B LEU -37 ? C LEU 17  
155 1 Y 1 B ALA -36 ? C ALA 18  
156 1 Y 1 B GLY -35 ? C GLY 19  
157 1 Y 1 B GLU -34 ? C GLU 20  
158 1 Y 1 B LEU -33 ? C LEU 21  
159 1 Y 1 B GLU -32 ? C GLU 22  
160 1 Y 1 B GLN -31 ? C GLN 23  
161 1 Y 1 B LEU -30 ? C LEU 24  
162 1 Y 1 B ARG -29 ? C ARG 25  
163 1 Y 1 B ALA -28 ? C ALA 26  
164 1 Y 1 B ARG -27 ? C ARG 27  
165 1 Y 1 B LEU -26 ? C LEU 28  
166 1 Y 1 B GLU -25 ? C GLU 29  
167 1 Y 1 B HIS -24 ? C HIS 30  
168 1 Y 1 B HIS -23 ? C HIS 31  
169 1 Y 1 B PRO -22 ? C PRO 32  
170 1 Y 1 B GLN -21 ? C GLN 33  
171 1 Y 1 B GLY -20 ? C GLY 34  
172 1 Y 1 B GLN -19 ? C GLN 35  
173 1 Y 1 B ARG -18 ? C ARG 36  
174 1 Y 1 B GLU -17 ? C GLU 37  
175 1 Y 1 B PRO -16 ? C PRO 38  
176 1 Y 1 B ASP -15 ? C ASP 39  
177 1 Y 1 B TYR -14 ? C TYR 40  
178 1 Y 1 B ASP -13 ? C ASP 41  
179 1 Y 1 B ILE -12 ? C ILE 42  
180 1 Y 1 B PRO -11 ? C PRO 43  
181 1 Y 1 B THR -10 ? C THR 44  
182 1 Y 1 B THR -9  ? C THR 45  
183 1 Y 1 B GLU -8  ? C GLU 46  
184 1 Y 1 B ASN -7  ? C ASN 47  
185 1 Y 1 B LEU -6  ? C LEU 48  
186 1 Y 1 B TYR -5  ? C TYR 49  
187 1 Y 1 B PHE -4  ? C PHE 50  
188 1 Y 1 B GLN -3  ? C GLN 51  
189 1 Y 1 B GLY -2  ? C GLY 52  
190 1 Y 1 B THR -1  ? C THR 53  
191 1 Y 1 B GLY 0   ? C GLY 54  
192 1 Y 1 B GLN 1   ? C GLN 55  
193 1 Y 1 B SER 2   ? C SER 56  
194 1 Y 1 B VAL 3   ? C VAL 57  
195 1 Y 1 B ASN 4   ? C ASN 58  
196 1 Y 1 B ASP 5   ? C ASP 59  
197 1 Y 1 B PRO 6   ? C PRO 60  
198 1 Y 1 B GLY 7   ? C GLY 61  
199 1 Y 1 B ASN 448 ? C ASN 395 
200 1 Y 1 A MET -52 ? D MET 1   
201 1 Y 1 A ASP -51 ? D ASP 2   
202 1 Y 1 A GLU -50 ? D GLU 3   
203 1 Y 1 A LYS -49 ? D LYS 4   
204 1 Y 1 A THR -48 ? D THR 5   
205 1 Y 1 A THR -47 ? D THR 6   
206 1 Y 1 A GLY -46 ? D GLY 7   
207 1 Y 1 A TRP -45 ? D TRP 8   
208 1 Y 1 A ARG -44 ? D ARG 9   
209 1 Y 1 A GLY -43 ? D GLY 10  
210 1 Y 1 A GLY -42 ? D GLY 11  
211 1 Y 1 A HIS -41 ? D HIS 12  
212 1 Y 1 A VAL -40 ? D VAL 13  
213 1 Y 1 A VAL -39 ? D VAL 14  
214 1 Y 1 A GLU -38 ? D GLU 15  
215 1 Y 1 A GLY -37 ? D GLY 16  
216 1 Y 1 A LEU -36 ? D LEU 17  
217 1 Y 1 A ALA -35 ? D ALA 18  
218 1 Y 1 A GLY -34 ? D GLY 19  
219 1 Y 1 A GLU -33 ? D GLU 20  
220 1 Y 1 A LEU -32 ? D LEU 21  
221 1 Y 1 A GLU -31 ? D GLU 22  
222 1 Y 1 A GLN -30 ? D GLN 23  
223 1 Y 1 A LEU -29 ? D LEU 24  
224 1 Y 1 A ARG -28 ? D ARG 25  
225 1 Y 1 A ALA -27 ? D ALA 26  
226 1 Y 1 A ARG -26 ? D ARG 27  
227 1 Y 1 A LEU -25 ? D LEU 28  
228 1 Y 1 A GLU -24 ? D GLU 29  
229 1 Y 1 A HIS -23 ? D HIS 30  
230 1 Y 1 A HIS -22 ? D HIS 31  
231 1 Y 1 A PRO -21 ? D PRO 32  
232 1 Y 1 A GLN -20 ? D GLN 33  
233 1 Y 1 A GLY -19 ? D GLY 34  
234 1 Y 1 A GLN -18 ? D GLN 35  
235 1 Y 1 A ARG -17 ? D ARG 36  
236 1 Y 1 A GLU -16 ? D GLU 37  
237 1 Y 1 A PRO -15 ? D PRO 38  
238 1 Y 1 A ASP -14 ? D ASP 39  
239 1 Y 1 A TYR -13 ? D TYR 40  
240 1 Y 1 A ASP -12 ? D ASP 41  
241 1 Y 1 A ILE -11 ? D ILE 42  
242 1 Y 1 A PRO -10 ? D PRO 43  
243 1 Y 1 A THR -9  ? D THR 44  
244 1 Y 1 A THR -8  ? D THR 45  
245 1 Y 1 A GLU -7  ? D GLU 46  
246 1 Y 1 A ASN -6  ? D ASN 47  
247 1 Y 1 A LEU -5  ? D LEU 48  
248 1 Y 1 A TYR -4  ? D TYR 49  
249 1 Y 1 A PHE -3  ? D PHE 50  
250 1 Y 1 A GLN -2  ? D GLN 51  
251 1 Y 1 A GLY -1  ? D GLY 52  
252 1 Y 1 A THR 0   ? D THR 53  
253 1 Y 1 A GLY 1   ? D GLY 54  
254 1 Y 1 A GLN 2   ? D GLN 55  
255 1 Y 1 A PRO 3   ? D PRO 56  
256 1 Y 1 A SER 4   ? D SER 57  
257 1 Y 1 A GLN 5   ? D GLN 58  
258 1 Y 1 A ASP 6   ? D ASP 59  
259 1 Y 1 A GLU 7   ? D GLU 60  
260 1 Y 1 A LEU 8   ? D LEU 61  
261 1 Y 1 A LYS 9   ? D LYS 62  
262 1 Y 1 A ASP 10  ? D ASP 63  
263 1 Y 1 A ASN 11  ? D ASN 64  
264 1 Y 1 A GLU 419 ? D GLU 401 
265 1 Y 1 A PRO 420 ? D PRO 402 
266 1 Y 1 A GLN 421 ? D GLN 403 
267 1 Y 1 A LEU 422 ? D LEU 404 
268 1 Y 1 A LYS 423 ? D LYS 405 
269 1 Y 1 A ALA 424 ? D ALA 406 
270 1 Y 1 A PRO 425 ? D PRO 407 
271 1 Y 1 A THR 426 ? D THR 408 
272 1 Y 1 A PRO 427 ? D PRO 409 
273 1 Y 1 A HIS 428 ? D HIS 410 
274 1 Y 1 A GLN 429 ? D GLN 411 
275 1 Y 1 C MET -53 ? E MET 1   
276 1 Y 1 C ASP -52 ? E ASP 2   
277 1 Y 1 C GLU -51 ? E GLU 3   
278 1 Y 1 C LYS -50 ? E LYS 4   
279 1 Y 1 C THR -49 ? E THR 5   
280 1 Y 1 C THR -48 ? E THR 6   
281 1 Y 1 C GLY -47 ? E GLY 7   
282 1 Y 1 C TRP -46 ? E TRP 8   
283 1 Y 1 C ARG -45 ? E ARG 9   
284 1 Y 1 C GLY -44 ? E GLY 10  
285 1 Y 1 C GLY -43 ? E GLY 11  
286 1 Y 1 C HIS -42 ? E HIS 12  
287 1 Y 1 C VAL -41 ? E VAL 13  
288 1 Y 1 C VAL -40 ? E VAL 14  
289 1 Y 1 C GLU -39 ? E GLU 15  
290 1 Y 1 C GLY -38 ? E GLY 16  
291 1 Y 1 C LEU -37 ? E LEU 17  
292 1 Y 1 C ALA -36 ? E ALA 18  
293 1 Y 1 C GLY -35 ? E GLY 19  
294 1 Y 1 C GLU -34 ? E GLU 20  
295 1 Y 1 C LEU -33 ? E LEU 21  
296 1 Y 1 C GLU -32 ? E GLU 22  
297 1 Y 1 C GLN -31 ? E GLN 23  
298 1 Y 1 C LEU -30 ? E LEU 24  
299 1 Y 1 C ARG -29 ? E ARG 25  
300 1 Y 1 C ALA -28 ? E ALA 26  
301 1 Y 1 C ARG -27 ? E ARG 27  
302 1 Y 1 C LEU -26 ? E LEU 28  
303 1 Y 1 C GLU -25 ? E GLU 29  
304 1 Y 1 C HIS -24 ? E HIS 30  
305 1 Y 1 C HIS -23 ? E HIS 31  
306 1 Y 1 C PRO -22 ? E PRO 32  
307 1 Y 1 C GLN -21 ? E GLN 33  
308 1 Y 1 C GLY -20 ? E GLY 34  
309 1 Y 1 C GLN -19 ? E GLN 35  
310 1 Y 1 C ARG -18 ? E ARG 36  
311 1 Y 1 C GLU -17 ? E GLU 37  
312 1 Y 1 C PRO -16 ? E PRO 38  
313 1 Y 1 C ASP -15 ? E ASP 39  
314 1 Y 1 C TYR -14 ? E TYR 40  
315 1 Y 1 C ASP -13 ? E ASP 41  
316 1 Y 1 C ILE -12 ? E ILE 42  
317 1 Y 1 C PRO -11 ? E PRO 43  
318 1 Y 1 C THR -10 ? E THR 44  
319 1 Y 1 C THR -9  ? E THR 45  
320 1 Y 1 C GLU -8  ? E GLU 46  
321 1 Y 1 C ASN -7  ? E ASN 47  
322 1 Y 1 C LEU -6  ? E LEU 48  
323 1 Y 1 C TYR -5  ? E TYR 49  
324 1 Y 1 C PHE -4  ? E PHE 50  
325 1 Y 1 C GLN -3  ? E GLN 51  
326 1 Y 1 C GLY -2  ? E GLY 52  
327 1 Y 1 C THR -1  ? E THR 53  
328 1 Y 1 C GLY 0   ? E GLY 54  
329 1 Y 1 C GLN 1   ? E GLN 55  
330 1 Y 1 C SER 2   ? E SER 56  
331 1 Y 1 C VAL 3   ? E VAL 57  
332 1 Y 1 C ASN 4   ? E ASN 58  
333 1 Y 1 C ASP 5   ? E ASP 59  
334 1 Y 1 C PRO 6   ? E PRO 60  
335 1 Y 1 C GLY 7   ? E GLY 61  
336 1 Y 1 C ASN 448 ? E ASN 395 
337 1 Y 1 F GLY 10  ? F GLY 9   
338 1 Y 1 F GLY 11  ? F GLY 10  
339 1 Y 1 F LEU 12  ? F LEU 11  
340 1 Y 1 F VAL 13  ? F VAL 12  
341 1 Y 1 F GLN 14  ? F GLN 13  
342 1 Y 1 F THR 15  ? F THR 14  
343 1 Y 1 F LYS 16  ? F LYS 15  
344 1 Y 1 F THR 17  ? F THR 16  
345 1 Y 1 F THR 18  ? F THR 17  
346 1 Y 1 F THR 19  ? F THR 18  
347 1 Y 1 F SER 20  ? F SER 19  
348 1 Y 1 F VAL 21  ? F VAL 20  
349 1 Y 1 F ILE 22  ? F ILE 21  
350 1 Y 1 F ASP 23  ? F ASP 22  
351 1 Y 1 F THR 24  ? F THR 23  
352 1 Y 1 F THR 25  ? F THR 24  
353 1 Y 1 F ASN 26  ? F ASN 25  
354 1 Y 1 F ASP 27  ? F ASP 26  
355 1 Y 1 F ALA 28  ? F ALA 27  
356 1 Y 1 F GLN 29  ? F GLN 28  
357 1 Y 1 F ASN 30  ? F ASN 29  
358 1 Y 1 F LEU 31  ? F LEU 30  
359 1 Y 1 F LEU 32  ? F LEU 31  
360 1 Y 1 F THR 33  ? F THR 32  
361 1 Y 1 F GLN 34  ? F GLN 33  
362 1 Y 1 F ALA 35  ? F ALA 34  
363 1 Y 1 F GLN 36  ? F GLN 35  
364 1 Y 1 F THR 37  ? F THR 36  
365 1 Y 1 F ILE 38  ? F ILE 37  
366 1 Y 1 F VAL 39  ? F VAL 38  
367 1 Y 1 F ASN 40  ? F ASN 39  
368 1 Y 1 F THR 41  ? F THR 40  
369 1 Y 1 F LEU 42  ? F LEU 41  
370 1 Y 1 F LYS 43  ? F LYS 42  
371 1 Y 1 F ASP 44  ? F ASP 43  
372 1 Y 1 F TYR 45  ? F TYR 44  
373 1 Y 1 F CYS 46  ? F CYS 45  
374 1 Y 1 F PRO 47  ? F PRO 46  
375 1 Y 1 F ILE 48  ? F ILE 47  
376 1 Y 1 F LEU 49  ? F LEU 48  
377 1 Y 1 F ILE 50  ? F ILE 49  
378 1 Y 1 F ALA 51  ? F ALA 50  
379 1 Y 1 F LYS 52  ? F LYS 51  
380 1 Y 1 F SER 53  ? F SER 52  
381 1 Y 1 F SER 54  ? F SER 53  
382 1 Y 1 F SER 55  ? F SER 54  
383 1 Y 1 F SER 56  ? F SER 55  
384 1 Y 1 F ASN 57  ? F ASN 56  
385 1 Y 1 F GLY 58  ? F GLY 57  
386 1 Y 1 F GLY 59  ? F GLY 58  
387 1 Y 1 F THR 60  ? F THR 59  
388 1 Y 1 F ASN 61  ? F ASN 60  
389 1 Y 1 F ASN 62  ? F ASN 61  
390 1 Y 1 F ALA 63  ? F ALA 62  
391 1 Y 1 F ASN 64  ? F ASN 63  
392 1 Y 1 F THR 65  ? F THR 64  
393 1 Y 1 F PRO 66  ? F PRO 65  
394 1 Y 1 F SER 67  ? F SER 66  
395 1 Y 1 F TRP 68  ? F TRP 67  
396 1 Y 1 F GLN 69  ? F GLN 68  
397 1 Y 1 F THR 70  ? F THR 69  
398 1 Y 1 F ALA 71  ? F ALA 70  
399 1 Y 1 F GLY 72  ? F GLY 71  
400 1 Y 1 F GLY 73  ? F GLY 72  
401 1 Y 1 F GLY 74  ? F GLY 73  
402 1 Y 1 F LYS 75  ? F LYS 74  
403 1 Y 1 F ASN 76  ? F ASN 75  
404 1 Y 1 F SER 77  ? F SER 76  
405 1 Y 1 F CYS 78  ? F CYS 77  
406 1 Y 1 F ALA 79  ? F ALA 78  
407 1 Y 1 F THR 80  ? F THR 79  
408 1 Y 1 F PHE 81  ? F PHE 80  
409 1 Y 1 F GLY 82  ? F GLY 81  
410 1 Y 1 F ALA 83  ? F ALA 82  
411 1 Y 1 F GLU 84  ? F GLU 83  
412 1 Y 1 F PHE 85  ? F PHE 84  
413 1 Y 1 F SER 86  ? F SER 85  
414 1 Y 1 F ALA 87  ? F ALA 86  
415 1 Y 1 F ALA 88  ? F ALA 87  
416 1 Y 1 F SER 89  ? F SER 88  
417 1 Y 1 F ASP 90  ? F ASP 89  
418 1 Y 1 F MET 91  ? F MET 90  
419 1 Y 1 F ILE 92  ? F ILE 91  
420 1 Y 1 F ASN 93  ? F ASN 92  
421 1 Y 1 F ASN 94  ? F ASN 93  
422 1 Y 1 F ALA 95  ? F ALA 94  
423 1 Y 1 F GLN 96  ? F GLN 95  
424 1 Y 1 F LYS 97  ? F LYS 96  
425 1 Y 1 F ILE 98  ? F ILE 97  
426 1 Y 1 F VAL 99  ? F VAL 98  
427 1 Y 1 F GLN 100 ? F GLN 99  
428 1 Y 1 F GLU 101 ? F GLU 100 
429 1 Y 1 F THR 102 ? F THR 101 
430 1 Y 1 F GLN 103 ? F GLN 102 
431 1 Y 1 F GLN 104 ? F GLN 103 
432 1 Y 1 F LEU 105 ? F LEU 104 
433 1 Y 1 F SER 106 ? F SER 105 
434 1 Y 1 F ALA 107 ? F ALA 106 
435 1 Y 1 F ASN 108 ? F ASN 107 
436 1 Y 1 F GLN 109 ? F GLN 108 
437 1 Y 1 F PRO 110 ? F PRO 109 
438 1 Y 1 F LYS 111 ? F LYS 110 
439 1 Y 1 F ASN 112 ? F ASN 111 
440 1 Y 1 F ILE 113 ? F ILE 112 
441 1 Y 1 F THR 114 ? F THR 113 
442 1 Y 1 F GLN 115 ? F GLN 114 
443 1 Y 1 F PRO 116 ? F PRO 115 
444 1 Y 1 F HIS 117 ? F HIS 116 
445 1 Y 1 F ASN 118 ? F ASN 117 
446 1 Y 1 F LEU 119 ? F LEU 118 
447 1 Y 1 F ASN 120 ? F ASN 119 
448 1 Y 1 F LEU 121 ? F LEU 120 
449 1 Y 1 F ASN 122 ? F ASN 121 
450 1 Y 1 F SER 123 ? F SER 122 
451 1 Y 1 F PRO 124 ? F PRO 123 
452 1 Y 1 F SER 125 ? F SER 124 
453 1 Y 1 F SER 126 ? F SER 125 
454 1 Y 1 F LEU 127 ? F LEU 126 
455 1 Y 1 F THR 128 ? F THR 127 
456 1 Y 1 F ALA 129 ? F ALA 128 
457 1 Y 1 F LEU 130 ? F LEU 129 
458 1 Y 1 F ALA 131 ? F ALA 130 
459 1 Y 1 F GLN 132 ? F GLN 131 
460 1 Y 1 F LYS 133 ? F LYS 132 
461 1 Y 1 F MET 134 ? F MET 133 
462 1 Y 1 F LEU 135 ? F LEU 134 
463 1 Y 1 F LYS 136 ? F LYS 135 
464 1 Y 1 F ASN 137 ? F ASN 136 
465 1 Y 1 F ALA 138 ? F ALA 137 
466 1 Y 1 F GLN 139 ? F GLN 138 
467 1 Y 1 F SER 140 ? F SER 139 
468 1 Y 1 F GLN 141 ? F GLN 140 
469 1 Y 1 F ALA 142 ? F ALA 141 
470 1 Y 1 F GLU 143 ? F GLU 142 
471 1 Y 1 F ILE 144 ? F ILE 143 
472 1 Y 1 F LEU 145 ? F LEU 144 
473 1 Y 1 F LYS 146 ? F LYS 145 
474 1 Y 1 F LEU 147 ? F LEU 146 
475 1 Y 1 F ALA 148 ? F ALA 147 
476 1 Y 1 F ASN 149 ? F ASN 148 
477 1 Y 1 F GLN 150 ? F GLN 149 
478 1 Y 1 F VAL 151 ? F VAL 150 
479 1 Y 1 F GLU 152 ? F GLU 151 
480 1 Y 1 F SER 153 ? F SER 152 
481 1 Y 1 F ASP 154 ? F ASP 153 
482 1 Y 1 F PHE 155 ? F PHE 154 
483 1 Y 1 F ASN 156 ? F ASN 155 
484 1 Y 1 F LYS 157 ? F LYS 156 
485 1 Y 1 F LEU 158 ? F LEU 157 
486 1 Y 1 F SER 159 ? F SER 158 
487 1 Y 1 F SER 160 ? F SER 159 
488 1 Y 1 F GLY 161 ? F GLY 160 
489 1 Y 1 F HIS 162 ? F HIS 161 
490 1 Y 1 F LEU 163 ? F LEU 162 
491 1 Y 1 F LYS 164 ? F LYS 163 
492 1 Y 1 F ASP 165 ? F ASP 164 
493 1 Y 1 F TYR 166 ? F TYR 165 
494 1 Y 1 F ILE 167 ? F ILE 166 
495 1 Y 1 F GLY 168 ? F GLY 167 
496 1 Y 1 F LYS 169 ? F LYS 168 
497 1 Y 1 F CYS 170 ? F CYS 169 
498 1 Y 1 F ASP 171 ? F ASP 170 
499 1 Y 1 F ALA 172 ? F ALA 171 
500 1 Y 1 F SER 173 ? F SER 172 
501 1 Y 1 F ALA 174 ? F ALA 173 
502 1 Y 1 F ILE 175 ? F ILE 174 
503 1 Y 1 F SER 176 ? F SER 175 
504 1 Y 1 F SER 177 ? F SER 176 
505 1 Y 1 F ALA 178 ? F ALA 177 
506 1 Y 1 F ASN 179 ? F ASN 178 
507 1 Y 1 F MET 180 ? F MET 179 
508 1 Y 1 F THR 181 ? F THR 180 
509 1 Y 1 F MET 182 ? F MET 181 
510 1 Y 1 F GLN 183 ? F GLN 182 
511 1 Y 1 F ASN 184 ? F ASN 183 
512 1 Y 1 F GLN 185 ? F GLN 184 
513 1 Y 1 F LYS 186 ? F LYS 185 
514 1 Y 1 F ASN 187 ? F ASN 186 
515 1 Y 1 F ASN 188 ? F ASN 187 
516 1 Y 1 F TRP 189 ? F TRP 188 
517 1 Y 1 F GLY 190 ? F GLY 189 
518 1 Y 1 F ASN 191 ? F ASN 190 
519 1 Y 1 F GLY 192 ? F GLY 191 
520 1 Y 1 F CYS 193 ? F CYS 192 
521 1 Y 1 F ALA 194 ? F ALA 193 
522 1 Y 1 F GLY 195 ? F GLY 194 
523 1 Y 1 F VAL 196 ? F VAL 195 
524 1 Y 1 F GLU 197 ? F GLU 196 
525 1 Y 1 F GLU 198 ? F GLU 197 
526 1 Y 1 F THR 199 ? F THR 198 
527 1 Y 1 F GLN 200 ? F GLN 199 
528 1 Y 1 F SER 201 ? F SER 200 
529 1 Y 1 F LEU 202 ? F LEU 201 
530 1 Y 1 F LEU 203 ? F LEU 202 
531 1 Y 1 F LYS 204 ? F LYS 203 
532 1 Y 1 F THR 205 ? F THR 204 
533 1 Y 1 F SER 206 ? F SER 205 
534 1 Y 1 F ALA 207 ? F ALA 206 
535 1 Y 1 F ALA 208 ? F ALA 207 
536 1 Y 1 F ASP 209 ? F ASP 208 
537 1 Y 1 F PHE 210 ? F PHE 209 
538 1 Y 1 F ASN 211 ? F ASN 210 
539 1 Y 1 F ASN 212 ? F ASN 211 
540 1 Y 1 F GLN 213 ? F GLN 212 
541 1 Y 1 F THR 214 ? F THR 213 
542 1 Y 1 F PRO 215 ? F PRO 214 
543 1 Y 1 F GLN 216 ? F GLN 215 
544 1 Y 1 F ILE 217 ? F ILE 216 
545 1 Y 1 F ASN 218 ? F ASN 217 
546 1 Y 1 F GLN 219 ? F GLN 218 
547 1 Y 1 F ALA 220 ? F ALA 219 
548 1 Y 1 F GLN 221 ? F GLN 220 
549 1 Y 1 F ASN 222 ? F ASN 221 
550 1 Y 1 F LEU 223 ? F LEU 222 
551 1 Y 1 F ALA 224 ? F ALA 223 
552 1 Y 1 F ASN 225 ? F ASN 224 
553 1 Y 1 F THR 226 ? F THR 225 
554 1 Y 1 F LEU 227 ? F LEU 226 
555 1 Y 1 F ILE 228 ? F ILE 227 
556 1 Y 1 F GLN 229 ? F GLN 228 
557 1 Y 1 F GLU 230 ? F GLU 229 
558 1 Y 1 F LEU 231 ? F LEU 230 
559 1 Y 1 F GLY 232 ? F GLY 231 
560 1 Y 1 F ASN 233 ? F ASN 232 
561 1 Y 1 F ASN 234 ? F ASN 233 
562 1 Y 1 F THR 235 ? F THR 234 
563 1 Y 1 F TYR 236 ? F TYR 235 
564 1 Y 1 F GLU 237 ? F GLU 236 
565 1 Y 1 F GLN 238 ? F GLN 237 
566 1 Y 1 F LEU 239 ? F LEU 238 
567 1 Y 1 F SER 240 ? F SER 239 
568 1 Y 1 F ARG 241 ? F ARG 240 
569 1 Y 1 F LEU 242 ? F LEU 241 
570 1 Y 1 F LEU 243 ? F LEU 242 
571 1 Y 1 F THR 244 ? F THR 243 
572 1 Y 1 F ASN 245 ? F ASN 244 
573 1 Y 1 F ASP 246 ? F ASP 245 
574 1 Y 1 F ASN 247 ? F ASN 246 
575 1 Y 1 F GLY 248 ? F GLY 247 
576 1 Y 1 F THR 249 ? F THR 248 
577 1 Y 1 F ASN 250 ? F ASN 249 
578 1 Y 1 F SER 251 ? F SER 250 
579 1 Y 1 F LYS 252 ? F LYS 251 
580 1 Y 1 F THR 253 ? F THR 252 
581 1 Y 1 F SER 254 ? F SER 253 
582 1 Y 1 F ALA 255 ? F ALA 254 
583 1 Y 1 F GLN 256 ? F GLN 255 
584 1 Y 1 F ALA 257 ? F ALA 256 
585 1 Y 1 F ILE 258 ? F ILE 257 
586 1 Y 1 F ASN 259 ? F ASN 258 
587 1 Y 1 F GLN 260 ? F GLN 259 
588 1 Y 1 F ALA 261 ? F ALA 260 
589 1 Y 1 F VAL 262 ? F VAL 261 
590 1 Y 1 F ASN 263 ? F ASN 262 
591 1 Y 1 F ASN 264 ? F ASN 263 
592 1 Y 1 F LEU 265 ? F LEU 264 
593 1 Y 1 F ASN 266 ? F ASN 265 
594 1 Y 1 F GLU 267 ? F GLU 266 
595 1 Y 1 F ARG 268 ? F ARG 267 
596 1 Y 1 F ALA 269 ? F ALA 268 
597 1 Y 1 F LYS 270 ? F LYS 269 
598 1 Y 1 F THR 271 ? F THR 270 
599 1 Y 1 F LEU 272 ? F LEU 271 
600 1 Y 1 F ALA 273 ? F ALA 272 
601 1 Y 1 F GLY 274 ? F GLY 273 
602 1 Y 1 F GLY 275 ? F GLY 274 
603 1 Y 1 F THR 276 ? F THR 275 
604 1 Y 1 F THR 277 ? F THR 276 
605 1 Y 1 F ASN 278 ? F ASN 277 
606 1 Y 1 F SER 279 ? F SER 278 
607 1 Y 1 F PRO 280 ? F PRO 279 
608 1 Y 1 F ALA 281 ? F ALA 280 
609 1 Y 1 F TYR 282 ? F TYR 281 
610 1 Y 1 F GLN 283 ? F GLN 282 
611 1 Y 1 F ALA 284 ? F ALA 283 
612 1 Y 1 F THR 285 ? F THR 284 
613 1 Y 1 F LEU 286 ? F LEU 285 
614 1 Y 1 F LEU 287 ? F LEU 286 
615 1 Y 1 F ALA 288 ? F ALA 287 
616 1 Y 1 F LEU 289 ? F LEU 288 
617 1 Y 1 F ARG 290 ? F ARG 289 
618 1 Y 1 F SER 291 ? F SER 290 
619 1 Y 1 F VAL 292 ? F VAL 291 
620 1 Y 1 F LEU 293 ? F LEU 292 
621 1 Y 1 F GLY 294 ? F GLY 293 
622 1 Y 1 F LEU 295 ? F LEU 294 
623 1 Y 1 F TRP 296 ? F TRP 295 
624 1 Y 1 F ASN 297 ? F ASN 296 
625 1 Y 1 F SER 298 ? F SER 297 
626 1 Y 1 F MET 299 ? F MET 298 
627 1 Y 1 F GLY 300 ? F GLY 299 
628 1 Y 1 F TYR 301 ? F TYR 300 
629 1 Y 1 F ALA 302 ? F ALA 301 
630 1 Y 1 F VAL 303 ? F VAL 302 
631 1 Y 1 F ILE 304 ? F ILE 303 
632 1 Y 1 F CYS 305 ? F CYS 304 
633 1 Y 1 F GLY 306 ? F GLY 305 
634 1 Y 1 F GLY 307 ? F GLY 306 
635 1 Y 1 F TYR 308 ? F TYR 307 
636 1 Y 1 F THR 309 ? F THR 308 
637 1 Y 1 F LYS 310 ? F LYS 309 
638 1 Y 1 F SER 311 ? F SER 310 
639 1 Y 1 F PRO 312 ? F PRO 311 
640 1 Y 1 F GLY 313 ? F GLY 312 
641 1 Y 1 F GLU 314 ? F GLU 313 
642 1 Y 1 F ASN 315 ? F ASN 314 
643 1 Y 1 F ASN 316 ? F ASN 315 
644 1 Y 1 F GLN 317 ? F GLN 316 
645 1 Y 1 F LYS 318 ? F LYS 317 
646 1 Y 1 F ASP 319 ? F ASP 318 
647 1 Y 1 F PHE 320 ? F PHE 319 
648 1 Y 1 F HIS 321 ? F HIS 320 
649 1 Y 1 F TYR 322 ? F TYR 321 
650 1 Y 1 F THR 323 ? F THR 322 
651 1 Y 1 F ASP 324 ? F ASP 323 
652 1 Y 1 F GLU 325 ? F GLU 324 
653 1 Y 1 F ASN 326 ? F ASN 325 
654 1 Y 1 F GLY 327 ? F GLY 326 
655 1 Y 1 F ASN 328 ? F ASN 327 
656 1 Y 1 F GLY 329 ? F GLY 328 
657 1 Y 1 F THR 330 ? F THR 329 
658 1 Y 1 F THR 331 ? F THR 330 
659 1 Y 1 F ILE 332 ? F ILE 331 
660 1 Y 1 F ASN 333 ? F ASN 332 
661 1 Y 1 F CYS 334 ? F CYS 333 
662 1 Y 1 F GLY 335 ? F GLY 334 
663 1 Y 1 F GLY 336 ? F GLY 335 
664 1 Y 1 F SER 337 ? F SER 336 
665 1 Y 1 F THR 338 ? F THR 337 
666 1 Y 1 F ASN 339 ? F ASN 338 
667 1 Y 1 F SER 340 ? F SER 339 
668 1 Y 1 F ASN 341 ? F ASN 340 
669 1 Y 1 F GLY 342 ? F GLY 341 
670 1 Y 1 F THR 343 ? F THR 342 
671 1 Y 1 F HIS 344 ? F HIS 343 
672 1 Y 1 F SER 345 ? F SER 344 
673 1 Y 1 F TYR 346 ? F TYR 345 
674 1 Y 1 F ASN 347 ? F ASN 346 
675 1 Y 1 F GLY 348 ? F GLY 347 
676 1 Y 1 F THR 349 ? F THR 348 
677 1 Y 1 F ASN 350 ? F ASN 349 
678 1 Y 1 F THR 351 ? F THR 350 
679 1 Y 1 F LEU 352 ? F LEU 351 
680 1 Y 1 F LYS 353 ? F LYS 352 
681 1 Y 1 F ALA 354 ? F ALA 353 
682 1 Y 1 F ASP 355 ? F ASP 354 
683 1 Y 1 F LYS 356 ? F LYS 355 
684 1 Y 1 F ASN 357 ? F ASN 356 
685 1 Y 1 F VAL 358 ? F VAL 357 
686 1 Y 1 F SER 359 ? F SER 358 
687 1 Y 1 F LEU 360 ? F LEU 359 
688 1 Y 1 F SER 361 ? F SER 360 
689 1 Y 1 F ILE 362 ? F ILE 361 
690 1 Y 1 F GLU 363 ? F GLU 362 
691 1 Y 1 F GLN 364 ? F GLN 363 
692 1 Y 1 F TYR 365 ? F TYR 364 
693 1 Y 1 F GLU 366 ? F GLU 365 
694 1 Y 1 F LYS 367 ? F LYS 366 
695 1 Y 1 F ILE 368 ? F ILE 367 
696 1 Y 1 F HIS 369 ? F HIS 368 
697 1 Y 1 F GLU 370 ? F GLU 369 
698 1 Y 1 F ALA 371 ? F ALA 370 
699 1 Y 1 F TYR 372 ? F TYR 371 
700 1 Y 1 F GLN 373 ? F GLN 372 
701 1 Y 1 F ILE 374 ? F ILE 373 
702 1 Y 1 F LEU 375 ? F LEU 374 
703 1 Y 1 F SER 376 ? F SER 375 
704 1 Y 1 F LYS 377 ? F LYS 376 
705 1 Y 1 F ALA 378 ? F ALA 377 
706 1 Y 1 F LEU 379 ? F LEU 378 
707 1 Y 1 F LYS 380 ? F LYS 379 
708 1 Y 1 F GLN 381 ? F GLN 380 
709 1 Y 1 F ALA 382 ? F ALA 381 
710 1 Y 1 F GLY 383 ? F GLY 382 
711 1 Y 1 F LEU 384 ? F LEU 383 
712 1 Y 1 F ALA 385 ? F ALA 384 
713 1 Y 1 F PRO 386 ? F PRO 385 
714 1 Y 1 F LEU 387 ? F LEU 386 
715 1 Y 1 F ASN 388 ? F ASN 387 
716 1 Y 1 F SER 389 ? F SER 388 
717 1 Y 1 F LYS 390 ? F LYS 389 
718 1 Y 1 F GLY 391 ? F GLY 390 
719 1 Y 1 F GLU 392 ? F GLU 391 
720 1 Y 1 F LYS 393 ? F LYS 392 
721 1 Y 1 F LEU 394 ? F LEU 393 
722 1 Y 1 F GLU 395 ? F GLU 394 
723 1 Y 1 F ALA 396 ? F ALA 395 
724 1 Y 1 F HIS 397 ? F HIS 396 
725 1 Y 1 F VAL 398 ? F VAL 397 
726 1 Y 1 F THR 399 ? F THR 398 
727 1 Y 1 F THR 400 ? F THR 399 
728 1 Y 1 F SER 401 ? F SER 400 
729 1 Y 1 F LYS 402 ? F LYS 401 
730 1 Y 1 F TYR 403 ? F TYR 402 
731 1 Y 1 F GLY 404 ? F GLY 403 
732 1 Y 1 F SER 405 ? F SER 404 
733 1 Y 1 F VAL 511 ? F VAL 510 
734 1 Y 1 F SER 512 ? F SER 511 
735 1 Y 1 F SER 513 ? F SER 512 
736 1 Y 1 F HIS 514 ? F HIS 513 
737 1 Y 1 F HIS 515 ? F HIS 514 
738 1 Y 1 F HIS 516 ? F HIS 515 
739 1 Y 1 F HIS 517 ? F HIS 516 
740 1 Y 1 F HIS 518 ? F HIS 517 
741 1 Y 1 F HIS 519 ? F HIS 518 
742 1 Y 1 F GLU 520 ? F GLU 519 
743 1 Y 1 F PRO 521 ? F PRO 520 
744 1 Y 1 F GLU 522 ? F GLU 521 
745 1 Y 1 F ALA 523 ? F ALA 522 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ABU N    N  N N 1   
ABU CD   C  N N 2   
ABU CB   C  N N 3   
ABU CG   C  N N 4   
ABU C    C  N N 5   
ABU O    O  N N 6   
ABU OXT  O  N N 7   
ABU H    H  N N 8   
ABU H2   H  N N 9   
ABU HA1  H  N N 10  
ABU HA2  H  N N 11  
ABU HB1  H  N N 12  
ABU HB2  H  N N 13  
ABU HG1  H  N N 14  
ABU HG2  H  N N 15  
ABU HXT  H  N N 16  
ALA N    N  N N 17  
ALA CA   C  N S 18  
ALA C    C  N N 19  
ALA O    O  N N 20  
ALA CB   C  N N 21  
ALA OXT  O  N N 22  
ALA H    H  N N 23  
ALA H2   H  N N 24  
ALA HA   H  N N 25  
ALA HB1  H  N N 26  
ALA HB2  H  N N 27  
ALA HB3  H  N N 28  
ALA HXT  H  N N 29  
ARG N    N  N N 30  
ARG CA   C  N S 31  
ARG C    C  N N 32  
ARG O    O  N N 33  
ARG CB   C  N N 34  
ARG CG   C  N N 35  
ARG CD   C  N N 36  
ARG NE   N  N N 37  
ARG CZ   C  N N 38  
ARG NH1  N  N N 39  
ARG NH2  N  N N 40  
ARG OXT  O  N N 41  
ARG H    H  N N 42  
ARG H2   H  N N 43  
ARG HA   H  N N 44  
ARG HB2  H  N N 45  
ARG HB3  H  N N 46  
ARG HG2  H  N N 47  
ARG HG3  H  N N 48  
ARG HD2  H  N N 49  
ARG HD3  H  N N 50  
ARG HE   H  N N 51  
ARG HH11 H  N N 52  
ARG HH12 H  N N 53  
ARG HH21 H  N N 54  
ARG HH22 H  N N 55  
ARG HXT  H  N N 56  
ASN N    N  N N 57  
ASN CA   C  N S 58  
ASN C    C  N N 59  
ASN O    O  N N 60  
ASN CB   C  N N 61  
ASN CG   C  N N 62  
ASN OD1  O  N N 63  
ASN ND2  N  N N 64  
ASN OXT  O  N N 65  
ASN H    H  N N 66  
ASN H2   H  N N 67  
ASN HA   H  N N 68  
ASN HB2  H  N N 69  
ASN HB3  H  N N 70  
ASN HD21 H  N N 71  
ASN HD22 H  N N 72  
ASN HXT  H  N N 73  
ASP N    N  N N 74  
ASP CA   C  N S 75  
ASP C    C  N N 76  
ASP O    O  N N 77  
ASP CB   C  N N 78  
ASP CG   C  N N 79  
ASP OD1  O  N N 80  
ASP OD2  O  N N 81  
ASP OXT  O  N N 82  
ASP H    H  N N 83  
ASP H2   H  N N 84  
ASP HA   H  N N 85  
ASP HB2  H  N N 86  
ASP HB3  H  N N 87  
ASP HD2  H  N N 88  
ASP HXT  H  N N 89  
BMA C1   C  N R 90  
BMA C2   C  N S 91  
BMA C3   C  N S 92  
BMA C4   C  N S 93  
BMA C5   C  N R 94  
BMA C6   C  N N 95  
BMA O1   O  N N 96  
BMA O2   O  N N 97  
BMA O3   O  N N 98  
BMA O4   O  N N 99  
BMA O5   O  N N 100 
BMA O6   O  N N 101 
BMA H1   H  N N 102 
BMA H2   H  N N 103 
BMA H3   H  N N 104 
BMA H4   H  N N 105 
BMA H5   H  N N 106 
BMA H61  H  N N 107 
BMA H62  H  N N 108 
BMA HO1  H  N N 109 
BMA HO2  H  N N 110 
BMA HO3  H  N N 111 
BMA HO4  H  N N 112 
BMA HO6  H  N N 113 
CL  CL   CL N N 114 
CYS N    N  N N 115 
CYS CA   C  N R 116 
CYS C    C  N N 117 
CYS O    O  N N 118 
CYS CB   C  N N 119 
CYS SG   S  N N 120 
CYS OXT  O  N N 121 
CYS H    H  N N 122 
CYS H2   H  N N 123 
CYS HA   H  N N 124 
CYS HB2  H  N N 125 
CYS HB3  H  N N 126 
CYS HG   H  N N 127 
CYS HXT  H  N N 128 
GLN N    N  N N 129 
GLN CA   C  N S 130 
GLN C    C  N N 131 
GLN O    O  N N 132 
GLN CB   C  N N 133 
GLN CG   C  N N 134 
GLN CD   C  N N 135 
GLN OE1  O  N N 136 
GLN NE2  N  N N 137 
GLN OXT  O  N N 138 
GLN H    H  N N 139 
GLN H2   H  N N 140 
GLN HA   H  N N 141 
GLN HB2  H  N N 142 
GLN HB3  H  N N 143 
GLN HG2  H  N N 144 
GLN HG3  H  N N 145 
GLN HE21 H  N N 146 
GLN HE22 H  N N 147 
GLN HXT  H  N N 148 
GLU N    N  N N 149 
GLU CA   C  N S 150 
GLU C    C  N N 151 
GLU O    O  N N 152 
GLU CB   C  N N 153 
GLU CG   C  N N 154 
GLU CD   C  N N 155 
GLU OE1  O  N N 156 
GLU OE2  O  N N 157 
GLU OXT  O  N N 158 
GLU H    H  N N 159 
GLU H2   H  N N 160 
GLU HA   H  N N 161 
GLU HB2  H  N N 162 
GLU HB3  H  N N 163 
GLU HG2  H  N N 164 
GLU HG3  H  N N 165 
GLU HE2  H  N N 166 
GLU HXT  H  N N 167 
GLY N    N  N N 168 
GLY CA   C  N N 169 
GLY C    C  N N 170 
GLY O    O  N N 171 
GLY OXT  O  N N 172 
GLY H    H  N N 173 
GLY H2   H  N N 174 
GLY HA2  H  N N 175 
GLY HA3  H  N N 176 
GLY HXT  H  N N 177 
HIS N    N  N N 178 
HIS CA   C  N S 179 
HIS C    C  N N 180 
HIS O    O  N N 181 
HIS CB   C  N N 182 
HIS CG   C  Y N 183 
HIS ND1  N  Y N 184 
HIS CD2  C  Y N 185 
HIS CE1  C  Y N 186 
HIS NE2  N  Y N 187 
HIS OXT  O  N N 188 
HIS H    H  N N 189 
HIS H2   H  N N 190 
HIS HA   H  N N 191 
HIS HB2  H  N N 192 
HIS HB3  H  N N 193 
HIS HD1  H  N N 194 
HIS HD2  H  N N 195 
HIS HE1  H  N N 196 
HIS HE2  H  N N 197 
HIS HXT  H  N N 198 
ILE N    N  N N 199 
ILE CA   C  N S 200 
ILE C    C  N N 201 
ILE O    O  N N 202 
ILE CB   C  N S 203 
ILE CG1  C  N N 204 
ILE CG2  C  N N 205 
ILE CD1  C  N N 206 
ILE OXT  O  N N 207 
ILE H    H  N N 208 
ILE H2   H  N N 209 
ILE HA   H  N N 210 
ILE HB   H  N N 211 
ILE HG12 H  N N 212 
ILE HG13 H  N N 213 
ILE HG21 H  N N 214 
ILE HG22 H  N N 215 
ILE HG23 H  N N 216 
ILE HD11 H  N N 217 
ILE HD12 H  N N 218 
ILE HD13 H  N N 219 
ILE HXT  H  N N 220 
LEU N    N  N N 221 
LEU CA   C  N S 222 
LEU C    C  N N 223 
LEU O    O  N N 224 
LEU CB   C  N N 225 
LEU CG   C  N N 226 
LEU CD1  C  N N 227 
LEU CD2  C  N N 228 
LEU OXT  O  N N 229 
LEU H    H  N N 230 
LEU H2   H  N N 231 
LEU HA   H  N N 232 
LEU HB2  H  N N 233 
LEU HB3  H  N N 234 
LEU HG   H  N N 235 
LEU HD11 H  N N 236 
LEU HD12 H  N N 237 
LEU HD13 H  N N 238 
LEU HD21 H  N N 239 
LEU HD22 H  N N 240 
LEU HD23 H  N N 241 
LEU HXT  H  N N 242 
LYS N    N  N N 243 
LYS CA   C  N S 244 
LYS C    C  N N 245 
LYS O    O  N N 246 
LYS CB   C  N N 247 
LYS CG   C  N N 248 
LYS CD   C  N N 249 
LYS CE   C  N N 250 
LYS NZ   N  N N 251 
LYS OXT  O  N N 252 
LYS H    H  N N 253 
LYS H2   H  N N 254 
LYS HA   H  N N 255 
LYS HB2  H  N N 256 
LYS HB3  H  N N 257 
LYS HG2  H  N N 258 
LYS HG3  H  N N 259 
LYS HD2  H  N N 260 
LYS HD3  H  N N 261 
LYS HE2  H  N N 262 
LYS HE3  H  N N 263 
LYS HZ1  H  N N 264 
LYS HZ2  H  N N 265 
LYS HZ3  H  N N 266 
LYS HXT  H  N N 267 
MAN C1   C  N S 268 
MAN C2   C  N S 269 
MAN C3   C  N S 270 
MAN C4   C  N S 271 
MAN C5   C  N R 272 
MAN C6   C  N N 273 
MAN O1   O  N N 274 
MAN O2   O  N N 275 
MAN O3   O  N N 276 
MAN O4   O  N N 277 
MAN O5   O  N N 278 
MAN O6   O  N N 279 
MAN H1   H  N N 280 
MAN H2   H  N N 281 
MAN H3   H  N N 282 
MAN H4   H  N N 283 
MAN H5   H  N N 284 
MAN H61  H  N N 285 
MAN H62  H  N N 286 
MAN HO1  H  N N 287 
MAN HO2  H  N N 288 
MAN HO3  H  N N 289 
MAN HO4  H  N N 290 
MAN HO6  H  N N 291 
MET N    N  N N 292 
MET CA   C  N S 293 
MET C    C  N N 294 
MET O    O  N N 295 
MET CB   C  N N 296 
MET CG   C  N N 297 
MET SD   S  N N 298 
MET CE   C  N N 299 
MET OXT  O  N N 300 
MET H    H  N N 301 
MET H2   H  N N 302 
MET HA   H  N N 303 
MET HB2  H  N N 304 
MET HB3  H  N N 305 
MET HG2  H  N N 306 
MET HG3  H  N N 307 
MET HE1  H  N N 308 
MET HE2  H  N N 309 
MET HE3  H  N N 310 
MET HXT  H  N N 311 
NAG C1   C  N R 312 
NAG C2   C  N R 313 
NAG C3   C  N R 314 
NAG C4   C  N S 315 
NAG C5   C  N R 316 
NAG C6   C  N N 317 
NAG C7   C  N N 318 
NAG C8   C  N N 319 
NAG N2   N  N N 320 
NAG O1   O  N N 321 
NAG O3   O  N N 322 
NAG O4   O  N N 323 
NAG O5   O  N N 324 
NAG O6   O  N N 325 
NAG O7   O  N N 326 
NAG H1   H  N N 327 
NAG H2   H  N N 328 
NAG H3   H  N N 329 
NAG H4   H  N N 330 
NAG H5   H  N N 331 
NAG H61  H  N N 332 
NAG H62  H  N N 333 
NAG H81  H  N N 334 
NAG H82  H  N N 335 
NAG H83  H  N N 336 
NAG HN2  H  N N 337 
NAG HO1  H  N N 338 
NAG HO3  H  N N 339 
NAG HO4  H  N N 340 
NAG HO6  H  N N 341 
PHE N    N  N N 342 
PHE CA   C  N S 343 
PHE C    C  N N 344 
PHE O    O  N N 345 
PHE CB   C  N N 346 
PHE CG   C  Y N 347 
PHE CD1  C  Y N 348 
PHE CD2  C  Y N 349 
PHE CE1  C  Y N 350 
PHE CE2  C  Y N 351 
PHE CZ   C  Y N 352 
PHE OXT  O  N N 353 
PHE H    H  N N 354 
PHE H2   H  N N 355 
PHE HA   H  N N 356 
PHE HB2  H  N N 357 
PHE HB3  H  N N 358 
PHE HD1  H  N N 359 
PHE HD2  H  N N 360 
PHE HE1  H  N N 361 
PHE HE2  H  N N 362 
PHE HZ   H  N N 363 
PHE HXT  H  N N 364 
PRO N    N  N N 365 
PRO CA   C  N S 366 
PRO C    C  N N 367 
PRO O    O  N N 368 
PRO CB   C  N N 369 
PRO CG   C  N N 370 
PRO CD   C  N N 371 
PRO OXT  O  N N 372 
PRO H    H  N N 373 
PRO HA   H  N N 374 
PRO HB2  H  N N 375 
PRO HB3  H  N N 376 
PRO HG2  H  N N 377 
PRO HG3  H  N N 378 
PRO HD2  H  N N 379 
PRO HD3  H  N N 380 
PRO HXT  H  N N 381 
SER N    N  N N 382 
SER CA   C  N S 383 
SER C    C  N N 384 
SER O    O  N N 385 
SER CB   C  N N 386 
SER OG   O  N N 387 
SER OXT  O  N N 388 
SER H    H  N N 389 
SER H2   H  N N 390 
SER HA   H  N N 391 
SER HB2  H  N N 392 
SER HB3  H  N N 393 
SER HG   H  N N 394 
SER HXT  H  N N 395 
THR N    N  N N 396 
THR CA   C  N S 397 
THR C    C  N N 398 
THR O    O  N N 399 
THR CB   C  N R 400 
THR OG1  O  N N 401 
THR CG2  C  N N 402 
THR OXT  O  N N 403 
THR H    H  N N 404 
THR H2   H  N N 405 
THR HA   H  N N 406 
THR HB   H  N N 407 
THR HG1  H  N N 408 
THR HG21 H  N N 409 
THR HG22 H  N N 410 
THR HG23 H  N N 411 
THR HXT  H  N N 412 
TRP N    N  N N 413 
TRP CA   C  N S 414 
TRP C    C  N N 415 
TRP O    O  N N 416 
TRP CB   C  N N 417 
TRP CG   C  Y N 418 
TRP CD1  C  Y N 419 
TRP CD2  C  Y N 420 
TRP NE1  N  Y N 421 
TRP CE2  C  Y N 422 
TRP CE3  C  Y N 423 
TRP CZ2  C  Y N 424 
TRP CZ3  C  Y N 425 
TRP CH2  C  Y N 426 
TRP OXT  O  N N 427 
TRP H    H  N N 428 
TRP H2   H  N N 429 
TRP HA   H  N N 430 
TRP HB2  H  N N 431 
TRP HB3  H  N N 432 
TRP HD1  H  N N 433 
TRP HE1  H  N N 434 
TRP HE3  H  N N 435 
TRP HZ2  H  N N 436 
TRP HZ3  H  N N 437 
TRP HH2  H  N N 438 
TRP HXT  H  N N 439 
TYR N    N  N N 440 
TYR CA   C  N S 441 
TYR C    C  N N 442 
TYR O    O  N N 443 
TYR CB   C  N N 444 
TYR CG   C  Y N 445 
TYR CD1  C  Y N 446 
TYR CD2  C  Y N 447 
TYR CE1  C  Y N 448 
TYR CE2  C  Y N 449 
TYR CZ   C  Y N 450 
TYR OH   O  N N 451 
TYR OXT  O  N N 452 
TYR H    H  N N 453 
TYR H2   H  N N 454 
TYR HA   H  N N 455 
TYR HB2  H  N N 456 
TYR HB3  H  N N 457 
TYR HD1  H  N N 458 
TYR HD2  H  N N 459 
TYR HE1  H  N N 460 
TYR HE2  H  N N 461 
TYR HH   H  N N 462 
TYR HXT  H  N N 463 
VAL N    N  N N 464 
VAL CA   C  N S 465 
VAL C    C  N N 466 
VAL O    O  N N 467 
VAL CB   C  N N 468 
VAL CG1  C  N N 469 
VAL CG2  C  N N 470 
VAL OXT  O  N N 471 
VAL H    H  N N 472 
VAL H2   H  N N 473 
VAL HA   H  N N 474 
VAL HB   H  N N 475 
VAL HG11 H  N N 476 
VAL HG12 H  N N 477 
VAL HG13 H  N N 478 
VAL HG21 H  N N 479 
VAL HG22 H  N N 480 
VAL HG23 H  N N 481 
VAL HXT  H  N N 482 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ABU N   CD   sing N N 1   
ABU N   H    sing N N 2   
ABU N   H2   sing N N 3   
ABU CD  CB   sing N N 4   
ABU CD  HA1  sing N N 5   
ABU CD  HA2  sing N N 6   
ABU CB  CG   sing N N 7   
ABU CB  HB1  sing N N 8   
ABU CB  HB2  sing N N 9   
ABU CG  C    sing N N 10  
ABU CG  HG1  sing N N 11  
ABU CG  HG2  sing N N 12  
ABU C   O    doub N N 13  
ABU C   OXT  sing N N 14  
ABU OXT HXT  sing N N 15  
ALA N   CA   sing N N 16  
ALA N   H    sing N N 17  
ALA N   H2   sing N N 18  
ALA CA  C    sing N N 19  
ALA CA  CB   sing N N 20  
ALA CA  HA   sing N N 21  
ALA C   O    doub N N 22  
ALA C   OXT  sing N N 23  
ALA CB  HB1  sing N N 24  
ALA CB  HB2  sing N N 25  
ALA CB  HB3  sing N N 26  
ALA OXT HXT  sing N N 27  
ARG N   CA   sing N N 28  
ARG N   H    sing N N 29  
ARG N   H2   sing N N 30  
ARG CA  C    sing N N 31  
ARG CA  CB   sing N N 32  
ARG CA  HA   sing N N 33  
ARG C   O    doub N N 34  
ARG C   OXT  sing N N 35  
ARG CB  CG   sing N N 36  
ARG CB  HB2  sing N N 37  
ARG CB  HB3  sing N N 38  
ARG CG  CD   sing N N 39  
ARG CG  HG2  sing N N 40  
ARG CG  HG3  sing N N 41  
ARG CD  NE   sing N N 42  
ARG CD  HD2  sing N N 43  
ARG CD  HD3  sing N N 44  
ARG NE  CZ   sing N N 45  
ARG NE  HE   sing N N 46  
ARG CZ  NH1  sing N N 47  
ARG CZ  NH2  doub N N 48  
ARG NH1 HH11 sing N N 49  
ARG NH1 HH12 sing N N 50  
ARG NH2 HH21 sing N N 51  
ARG NH2 HH22 sing N N 52  
ARG OXT HXT  sing N N 53  
ASN N   CA   sing N N 54  
ASN N   H    sing N N 55  
ASN N   H2   sing N N 56  
ASN CA  C    sing N N 57  
ASN CA  CB   sing N N 58  
ASN CA  HA   sing N N 59  
ASN C   O    doub N N 60  
ASN C   OXT  sing N N 61  
ASN CB  CG   sing N N 62  
ASN CB  HB2  sing N N 63  
ASN CB  HB3  sing N N 64  
ASN CG  OD1  doub N N 65  
ASN CG  ND2  sing N N 66  
ASN ND2 HD21 sing N N 67  
ASN ND2 HD22 sing N N 68  
ASN OXT HXT  sing N N 69  
ASP N   CA   sing N N 70  
ASP N   H    sing N N 71  
ASP N   H2   sing N N 72  
ASP CA  C    sing N N 73  
ASP CA  CB   sing N N 74  
ASP CA  HA   sing N N 75  
ASP C   O    doub N N 76  
ASP C   OXT  sing N N 77  
ASP CB  CG   sing N N 78  
ASP CB  HB2  sing N N 79  
ASP CB  HB3  sing N N 80  
ASP CG  OD1  doub N N 81  
ASP CG  OD2  sing N N 82  
ASP OD2 HD2  sing N N 83  
ASP OXT HXT  sing N N 84  
BMA C1  C2   sing N N 85  
BMA C1  O1   sing N N 86  
BMA C1  O5   sing N N 87  
BMA C1  H1   sing N N 88  
BMA C2  C3   sing N N 89  
BMA C2  O2   sing N N 90  
BMA C2  H2   sing N N 91  
BMA C3  C4   sing N N 92  
BMA C3  O3   sing N N 93  
BMA C3  H3   sing N N 94  
BMA C4  C5   sing N N 95  
BMA C4  O4   sing N N 96  
BMA C4  H4   sing N N 97  
BMA C5  C6   sing N N 98  
BMA C5  O5   sing N N 99  
BMA C5  H5   sing N N 100 
BMA C6  O6   sing N N 101 
BMA C6  H61  sing N N 102 
BMA C6  H62  sing N N 103 
BMA O1  HO1  sing N N 104 
BMA O2  HO2  sing N N 105 
BMA O3  HO3  sing N N 106 
BMA O4  HO4  sing N N 107 
BMA O6  HO6  sing N N 108 
CYS N   CA   sing N N 109 
CYS N   H    sing N N 110 
CYS N   H2   sing N N 111 
CYS CA  C    sing N N 112 
CYS CA  CB   sing N N 113 
CYS CA  HA   sing N N 114 
CYS C   O    doub N N 115 
CYS C   OXT  sing N N 116 
CYS CB  SG   sing N N 117 
CYS CB  HB2  sing N N 118 
CYS CB  HB3  sing N N 119 
CYS SG  HG   sing N N 120 
CYS OXT HXT  sing N N 121 
GLN N   CA   sing N N 122 
GLN N   H    sing N N 123 
GLN N   H2   sing N N 124 
GLN CA  C    sing N N 125 
GLN CA  CB   sing N N 126 
GLN CA  HA   sing N N 127 
GLN C   O    doub N N 128 
GLN C   OXT  sing N N 129 
GLN CB  CG   sing N N 130 
GLN CB  HB2  sing N N 131 
GLN CB  HB3  sing N N 132 
GLN CG  CD   sing N N 133 
GLN CG  HG2  sing N N 134 
GLN CG  HG3  sing N N 135 
GLN CD  OE1  doub N N 136 
GLN CD  NE2  sing N N 137 
GLN NE2 HE21 sing N N 138 
GLN NE2 HE22 sing N N 139 
GLN OXT HXT  sing N N 140 
GLU N   CA   sing N N 141 
GLU N   H    sing N N 142 
GLU N   H2   sing N N 143 
GLU CA  C    sing N N 144 
GLU CA  CB   sing N N 145 
GLU CA  HA   sing N N 146 
GLU C   O    doub N N 147 
GLU C   OXT  sing N N 148 
GLU CB  CG   sing N N 149 
GLU CB  HB2  sing N N 150 
GLU CB  HB3  sing N N 151 
GLU CG  CD   sing N N 152 
GLU CG  HG2  sing N N 153 
GLU CG  HG3  sing N N 154 
GLU CD  OE1  doub N N 155 
GLU CD  OE2  sing N N 156 
GLU OE2 HE2  sing N N 157 
GLU OXT HXT  sing N N 158 
GLY N   CA   sing N N 159 
GLY N   H    sing N N 160 
GLY N   H2   sing N N 161 
GLY CA  C    sing N N 162 
GLY CA  HA2  sing N N 163 
GLY CA  HA3  sing N N 164 
GLY C   O    doub N N 165 
GLY C   OXT  sing N N 166 
GLY OXT HXT  sing N N 167 
HIS N   CA   sing N N 168 
HIS N   H    sing N N 169 
HIS N   H2   sing N N 170 
HIS CA  C    sing N N 171 
HIS CA  CB   sing N N 172 
HIS CA  HA   sing N N 173 
HIS C   O    doub N N 174 
HIS C   OXT  sing N N 175 
HIS CB  CG   sing N N 176 
HIS CB  HB2  sing N N 177 
HIS CB  HB3  sing N N 178 
HIS CG  ND1  sing Y N 179 
HIS CG  CD2  doub Y N 180 
HIS ND1 CE1  doub Y N 181 
HIS ND1 HD1  sing N N 182 
HIS CD2 NE2  sing Y N 183 
HIS CD2 HD2  sing N N 184 
HIS CE1 NE2  sing Y N 185 
HIS CE1 HE1  sing N N 186 
HIS NE2 HE2  sing N N 187 
HIS OXT HXT  sing N N 188 
ILE N   CA   sing N N 189 
ILE N   H    sing N N 190 
ILE N   H2   sing N N 191 
ILE CA  C    sing N N 192 
ILE CA  CB   sing N N 193 
ILE CA  HA   sing N N 194 
ILE C   O    doub N N 195 
ILE C   OXT  sing N N 196 
ILE CB  CG1  sing N N 197 
ILE CB  CG2  sing N N 198 
ILE CB  HB   sing N N 199 
ILE CG1 CD1  sing N N 200 
ILE CG1 HG12 sing N N 201 
ILE CG1 HG13 sing N N 202 
ILE CG2 HG21 sing N N 203 
ILE CG2 HG22 sing N N 204 
ILE CG2 HG23 sing N N 205 
ILE CD1 HD11 sing N N 206 
ILE CD1 HD12 sing N N 207 
ILE CD1 HD13 sing N N 208 
ILE OXT HXT  sing N N 209 
LEU N   CA   sing N N 210 
LEU N   H    sing N N 211 
LEU N   H2   sing N N 212 
LEU CA  C    sing N N 213 
LEU CA  CB   sing N N 214 
LEU CA  HA   sing N N 215 
LEU C   O    doub N N 216 
LEU C   OXT  sing N N 217 
LEU CB  CG   sing N N 218 
LEU CB  HB2  sing N N 219 
LEU CB  HB3  sing N N 220 
LEU CG  CD1  sing N N 221 
LEU CG  CD2  sing N N 222 
LEU CG  HG   sing N N 223 
LEU CD1 HD11 sing N N 224 
LEU CD1 HD12 sing N N 225 
LEU CD1 HD13 sing N N 226 
LEU CD2 HD21 sing N N 227 
LEU CD2 HD22 sing N N 228 
LEU CD2 HD23 sing N N 229 
LEU OXT HXT  sing N N 230 
LYS N   CA   sing N N 231 
LYS N   H    sing N N 232 
LYS N   H2   sing N N 233 
LYS CA  C    sing N N 234 
LYS CA  CB   sing N N 235 
LYS CA  HA   sing N N 236 
LYS C   O    doub N N 237 
LYS C   OXT  sing N N 238 
LYS CB  CG   sing N N 239 
LYS CB  HB2  sing N N 240 
LYS CB  HB3  sing N N 241 
LYS CG  CD   sing N N 242 
LYS CG  HG2  sing N N 243 
LYS CG  HG3  sing N N 244 
LYS CD  CE   sing N N 245 
LYS CD  HD2  sing N N 246 
LYS CD  HD3  sing N N 247 
LYS CE  NZ   sing N N 248 
LYS CE  HE2  sing N N 249 
LYS CE  HE3  sing N N 250 
LYS NZ  HZ1  sing N N 251 
LYS NZ  HZ2  sing N N 252 
LYS NZ  HZ3  sing N N 253 
LYS OXT HXT  sing N N 254 
MAN C1  C2   sing N N 255 
MAN C1  O1   sing N N 256 
MAN C1  O5   sing N N 257 
MAN C1  H1   sing N N 258 
MAN C2  C3   sing N N 259 
MAN C2  O2   sing N N 260 
MAN C2  H2   sing N N 261 
MAN C3  C4   sing N N 262 
MAN C3  O3   sing N N 263 
MAN C3  H3   sing N N 264 
MAN C4  C5   sing N N 265 
MAN C4  O4   sing N N 266 
MAN C4  H4   sing N N 267 
MAN C5  C6   sing N N 268 
MAN C5  O5   sing N N 269 
MAN C5  H5   sing N N 270 
MAN C6  O6   sing N N 271 
MAN C6  H61  sing N N 272 
MAN C6  H62  sing N N 273 
MAN O1  HO1  sing N N 274 
MAN O2  HO2  sing N N 275 
MAN O3  HO3  sing N N 276 
MAN O4  HO4  sing N N 277 
MAN O6  HO6  sing N N 278 
MET N   CA   sing N N 279 
MET N   H    sing N N 280 
MET N   H2   sing N N 281 
MET CA  C    sing N N 282 
MET CA  CB   sing N N 283 
MET CA  HA   sing N N 284 
MET C   O    doub N N 285 
MET C   OXT  sing N N 286 
MET CB  CG   sing N N 287 
MET CB  HB2  sing N N 288 
MET CB  HB3  sing N N 289 
MET CG  SD   sing N N 290 
MET CG  HG2  sing N N 291 
MET CG  HG3  sing N N 292 
MET SD  CE   sing N N 293 
MET CE  HE1  sing N N 294 
MET CE  HE2  sing N N 295 
MET CE  HE3  sing N N 296 
MET OXT HXT  sing N N 297 
NAG C1  C2   sing N N 298 
NAG C1  O1   sing N N 299 
NAG C1  O5   sing N N 300 
NAG C1  H1   sing N N 301 
NAG C2  C3   sing N N 302 
NAG C2  N2   sing N N 303 
NAG C2  H2   sing N N 304 
NAG C3  C4   sing N N 305 
NAG C3  O3   sing N N 306 
NAG C3  H3   sing N N 307 
NAG C4  C5   sing N N 308 
NAG C4  O4   sing N N 309 
NAG C4  H4   sing N N 310 
NAG C5  C6   sing N N 311 
NAG C5  O5   sing N N 312 
NAG C5  H5   sing N N 313 
NAG C6  O6   sing N N 314 
NAG C6  H61  sing N N 315 
NAG C6  H62  sing N N 316 
NAG C7  C8   sing N N 317 
NAG C7  N2   sing N N 318 
NAG C7  O7   doub N N 319 
NAG C8  H81  sing N N 320 
NAG C8  H82  sing N N 321 
NAG C8  H83  sing N N 322 
NAG N2  HN2  sing N N 323 
NAG O1  HO1  sing N N 324 
NAG O3  HO3  sing N N 325 
NAG O4  HO4  sing N N 326 
NAG O6  HO6  sing N N 327 
PHE N   CA   sing N N 328 
PHE N   H    sing N N 329 
PHE N   H2   sing N N 330 
PHE CA  C    sing N N 331 
PHE CA  CB   sing N N 332 
PHE CA  HA   sing N N 333 
PHE C   O    doub N N 334 
PHE C   OXT  sing N N 335 
PHE CB  CG   sing N N 336 
PHE CB  HB2  sing N N 337 
PHE CB  HB3  sing N N 338 
PHE CG  CD1  doub Y N 339 
PHE CG  CD2  sing Y N 340 
PHE CD1 CE1  sing Y N 341 
PHE CD1 HD1  sing N N 342 
PHE CD2 CE2  doub Y N 343 
PHE CD2 HD2  sing N N 344 
PHE CE1 CZ   doub Y N 345 
PHE CE1 HE1  sing N N 346 
PHE CE2 CZ   sing Y N 347 
PHE CE2 HE2  sing N N 348 
PHE CZ  HZ   sing N N 349 
PHE OXT HXT  sing N N 350 
PRO N   CA   sing N N 351 
PRO N   CD   sing N N 352 
PRO N   H    sing N N 353 
PRO CA  C    sing N N 354 
PRO CA  CB   sing N N 355 
PRO CA  HA   sing N N 356 
PRO C   O    doub N N 357 
PRO C   OXT  sing N N 358 
PRO CB  CG   sing N N 359 
PRO CB  HB2  sing N N 360 
PRO CB  HB3  sing N N 361 
PRO CG  CD   sing N N 362 
PRO CG  HG2  sing N N 363 
PRO CG  HG3  sing N N 364 
PRO CD  HD2  sing N N 365 
PRO CD  HD3  sing N N 366 
PRO OXT HXT  sing N N 367 
SER N   CA   sing N N 368 
SER N   H    sing N N 369 
SER N   H2   sing N N 370 
SER CA  C    sing N N 371 
SER CA  CB   sing N N 372 
SER CA  HA   sing N N 373 
SER C   O    doub N N 374 
SER C   OXT  sing N N 375 
SER CB  OG   sing N N 376 
SER CB  HB2  sing N N 377 
SER CB  HB3  sing N N 378 
SER OG  HG   sing N N 379 
SER OXT HXT  sing N N 380 
THR N   CA   sing N N 381 
THR N   H    sing N N 382 
THR N   H2   sing N N 383 
THR CA  C    sing N N 384 
THR CA  CB   sing N N 385 
THR CA  HA   sing N N 386 
THR C   O    doub N N 387 
THR C   OXT  sing N N 388 
THR CB  OG1  sing N N 389 
THR CB  CG2  sing N N 390 
THR CB  HB   sing N N 391 
THR OG1 HG1  sing N N 392 
THR CG2 HG21 sing N N 393 
THR CG2 HG22 sing N N 394 
THR CG2 HG23 sing N N 395 
THR OXT HXT  sing N N 396 
TRP N   CA   sing N N 397 
TRP N   H    sing N N 398 
TRP N   H2   sing N N 399 
TRP CA  C    sing N N 400 
TRP CA  CB   sing N N 401 
TRP CA  HA   sing N N 402 
TRP C   O    doub N N 403 
TRP C   OXT  sing N N 404 
TRP CB  CG   sing N N 405 
TRP CB  HB2  sing N N 406 
TRP CB  HB3  sing N N 407 
TRP CG  CD1  doub Y N 408 
TRP CG  CD2  sing Y N 409 
TRP CD1 NE1  sing Y N 410 
TRP CD1 HD1  sing N N 411 
TRP CD2 CE2  doub Y N 412 
TRP CD2 CE3  sing Y N 413 
TRP NE1 CE2  sing Y N 414 
TRP NE1 HE1  sing N N 415 
TRP CE2 CZ2  sing Y N 416 
TRP CE3 CZ3  doub Y N 417 
TRP CE3 HE3  sing N N 418 
TRP CZ2 CH2  doub Y N 419 
TRP CZ2 HZ2  sing N N 420 
TRP CZ3 CH2  sing Y N 421 
TRP CZ3 HZ3  sing N N 422 
TRP CH2 HH2  sing N N 423 
TRP OXT HXT  sing N N 424 
TYR N   CA   sing N N 425 
TYR N   H    sing N N 426 
TYR N   H2   sing N N 427 
TYR CA  C    sing N N 428 
TYR CA  CB   sing N N 429 
TYR CA  HA   sing N N 430 
TYR C   O    doub N N 431 
TYR C   OXT  sing N N 432 
TYR CB  CG   sing N N 433 
TYR CB  HB2  sing N N 434 
TYR CB  HB3  sing N N 435 
TYR CG  CD1  doub Y N 436 
TYR CG  CD2  sing Y N 437 
TYR CD1 CE1  sing Y N 438 
TYR CD1 HD1  sing N N 439 
TYR CD2 CE2  doub Y N 440 
TYR CD2 HD2  sing N N 441 
TYR CE1 CZ   doub Y N 442 
TYR CE1 HE1  sing N N 443 
TYR CE2 CZ   sing Y N 444 
TYR CE2 HE2  sing N N 445 
TYR CZ  OH   sing N N 446 
TYR OH  HH   sing N N 447 
TYR OXT HXT  sing N N 448 
VAL N   CA   sing N N 449 
VAL N   H    sing N N 450 
VAL N   H2   sing N N 451 
VAL CA  C    sing N N 452 
VAL CA  CB   sing N N 453 
VAL CA  HA   sing N N 454 
VAL C   O    doub N N 455 
VAL C   OXT  sing N N 456 
VAL CB  CG1  sing N N 457 
VAL CB  CG2  sing N N 458 
VAL CB  HB   sing N N 459 
VAL CG1 HG11 sing N N 460 
VAL CG1 HG12 sing N N 461 
VAL CG1 HG13 sing N N 462 
VAL CG2 HG21 sing N N 463 
VAL CG2 HG22 sing N N 464 
VAL CG2 HG23 sing N N 465 
VAL OXT HXT  sing N N 466 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-23 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9FFQ 
_em_admin.last_update        2025-06-04 
_em_admin.map_release_date   2025-06-04 
_em_admin.title              
;Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric desensitised state of branch 1
;
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 137 mM NaCl   1 'sodium chloride'    
1 2.7 mM KCl    2 'potassium chloride' 
1 4.3 mM Na2HPO 3 'Disodium phosphate' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.25 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               4.34 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'TFS FALCON 4i (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     18399 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   9725751 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? Topaz     ?         
'IMAGE ACQUISITION'        ? 2  ? ? 1 EPU       ?         
MASKING                    ? 3  ? ? ? ?         ?         
'CTF CORRECTION'           ? 4  1 ? ? CTFFIND   4.1       
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?         
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?         
'MODEL FITTING'            ? 7  ? 1 ? PHENIX    ?         
OTHER                      ? 8  ? ? ? ?         ?         
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX    1.21_5207 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? cryoSPARC ?         
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? cryoSPARC ?         
CLASSIFICATION             ? 12 1 ? ? cryoSPARC ?         
RECONSTRUCTION             ? 13 1 ? ? cryoSPARC ?         
# 
_em_specimen.concentration           1 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)'                                           'United Kingdom' MC_UP_1201/15       1 
'Cancer Research UK'                                                                       'United Kingdom' DRCRPG-May23/100002 2 
'Medical Research Council (MRC, United Kingdom)'                                           'United Kingdom' MR/L009609/1        3 
'Medical Research Council (MRC, United Kingdom)'                                           'United Kingdom' MC_EX_MR/T046279/1  4 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States'  1R01-GM135550       5 
'National Science Foundation (NSF, United States)'                                         'United States'  'NeuroNex 2014862'  6 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
4 NAG 1 n 
4 NAG 2 n 
4 BMA 3 n 
4 MAN 4 n 
4 MAN 5 n 
5 NAG 1 n 
5 NAG 2 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6HUK 
# 
_atom_sites.entry_id                    9FFQ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . THR A 1 65  ? 123.665 99.912  75.136  1.00 71.99  ? 12  THR D N   1 
ATOM   2     C  CA  . THR A 1 65  ? 123.899 101.179 75.814  1.00 76.89  ? 12  THR D CA  1 
ATOM   3     C  C   . THR A 1 65  ? 123.719 102.341 74.839  1.00 75.71  ? 12  THR D C   1 
ATOM   4     O  O   . THR A 1 65  ? 123.310 103.434 75.227  1.00 75.38  ? 12  THR D O   1 
ATOM   5     C  CB  . THR A 1 65  ? 125.304 101.225 76.443  1.00 77.03  ? 12  THR D CB  1 
ATOM   6     O  OG1 . THR A 1 65  ? 125.447 100.138 77.366  1.00 74.82  ? 12  THR D OG1 1 
ATOM   7     C  CG2 . THR A 1 65  ? 125.529 102.531 77.181  1.00 70.44  ? 12  THR D CG2 1 
ATOM   8     N  N   . THR A 1 66  ? 124.016 102.091 73.564  1.00 72.49  ? 13  THR D N   1 
ATOM   9     C  CA  . THR A 1 66  ? 123.797 103.110 72.542  1.00 70.64  ? 13  THR D CA  1 
ATOM   10    C  C   . THR A 1 66  ? 122.312 103.399 72.362  1.00 71.08  ? 13  THR D C   1 
ATOM   11    O  O   . THR A 1 66  ? 121.921 104.544 72.107  1.00 69.38  ? 13  THR D O   1 
ATOM   12    C  CB  . THR A 1 66  ? 124.424 102.669 71.223  1.00 72.61  ? 13  THR D CB  1 
ATOM   13    O  OG1 . THR A 1 66  ? 125.810 102.378 71.432  1.00 77.79  ? 13  THR D OG1 1 
ATOM   14    C  CG2 . THR A 1 66  ? 124.299 103.765 70.180  1.00 69.77  ? 13  THR D CG2 1 
ATOM   15    N  N   . VAL A 1 67  ? 121.471 102.372 72.499  1.00 72.00  ? 14  VAL D N   1 
ATOM   16    C  CA  . VAL A 1 67  ? 120.028 102.563 72.390  1.00 70.64  ? 14  VAL D CA  1 
ATOM   17    C  C   . VAL A 1 67  ? 119.545 103.539 73.453  1.00 66.88  ? 14  VAL D C   1 
ATOM   18    O  O   . VAL A 1 67  ? 118.767 104.461 73.174  1.00 68.52  ? 14  VAL D O   1 
ATOM   19    C  CB  . VAL A 1 67  ? 119.304 101.210 72.503  1.00 70.65  ? 14  VAL D CB  1 
ATOM   20    C  CG1 . VAL A 1 67  ? 117.802 101.401 72.449  1.00 67.74  ? 14  VAL D CG1 1 
ATOM   21    C  CG2 . VAL A 1 67  ? 119.761 100.274 71.406  1.00 74.76  ? 14  VAL D CG2 1 
ATOM   22    N  N   . PHE A 1 68  ? 120.007 103.356 74.689  1.00 64.42  ? 15  PHE D N   1 
ATOM   23    C  CA  . PHE A 1 68  ? 119.569 104.220 75.776  1.00 62.64  ? 15  PHE D CA  1 
ATOM   24    C  C   . PHE A 1 68  ? 120.120 105.631 75.635  1.00 61.11  ? 15  PHE D C   1 
ATOM   25    O  O   . PHE A 1 68  ? 119.443 106.598 76.003  1.00 59.74  ? 15  PHE D O   1 
ATOM   26    C  CB  . PHE A 1 68  ? 119.969 103.609 77.112  1.00 64.78  ? 15  PHE D CB  1 
ATOM   27    C  CG  . PHE A 1 68  ? 119.461 102.212 77.306  1.00 68.17  ? 15  PHE D CG  1 
ATOM   28    C  CD1 . PHE A 1 68  ? 118.115 101.973 77.507  1.00 66.11  ? 15  PHE D CD1 1 
ATOM   29    C  CD2 . PHE A 1 68  ? 120.328 101.137 77.283  1.00 70.37  ? 15  PHE D CD2 1 
ATOM   30    C  CE1 . PHE A 1 68  ? 117.649 100.692 77.684  1.00 68.39  ? 15  PHE D CE1 1 
ATOM   31    C  CE2 . PHE A 1 68  ? 119.865 99.854  77.460  1.00 69.83  ? 15  PHE D CE2 1 
ATOM   32    C  CZ  . PHE A 1 68  ? 118.526 99.631  77.661  1.00 69.55  ? 15  PHE D CZ  1 
ATOM   33    N  N   . THR A 1 69  ? 121.335 105.774 75.106  1.00 59.32  ? 16  THR D N   1 
ATOM   34    C  CA  . THR A 1 69  ? 121.858 107.108 74.835  1.00 60.26  ? 16  THR D CA  1 
ATOM   35    C  C   . THR A 1 69  ? 121.021 107.819 73.780  1.00 62.58  ? 16  THR D C   1 
ATOM   36    O  O   . THR A 1 69  ? 120.705 109.006 73.924  1.00 63.84  ? 16  THR D O   1 
ATOM   37    C  CB  . THR A 1 69  ? 123.319 107.023 74.404  1.00 63.08  ? 16  THR D CB  1 
ATOM   38    O  OG1 . THR A 1 69  ? 124.087 106.427 75.454  1.00 66.52  ? 16  THR D OG1 1 
ATOM   39    C  CG2 . THR A 1 69  ? 123.868 108.403 74.126  1.00 59.28  ? 16  THR D CG2 1 
ATOM   40    N  N   . ARG A 1 70  ? 120.634 107.104 72.722  1.00 63.37  ? 17  ARG D N   1 
ATOM   41    C  CA  . ARG A 1 70  ? 119.752 107.697 71.723  1.00 61.65  ? 17  ARG D CA  1 
ATOM   42    C  C   . ARG A 1 70  ? 118.422 108.104 72.340  1.00 60.30  ? 17  ARG D C   1 
ATOM   43    O  O   . ARG A 1 70  ? 117.884 109.173 72.027  1.00 63.41  ? 17  ARG D O   1 
ATOM   44    C  CB  . ARG A 1 70  ? 119.520 106.722 70.572  1.00 62.44  ? 17  ARG D CB  1 
ATOM   45    C  CG  . ARG A 1 70  ? 120.749 106.398 69.762  1.00 68.09  ? 17  ARG D CG  1 
ATOM   46    C  CD  . ARG A 1 70  ? 120.362 105.705 68.468  1.00 77.12  ? 17  ARG D CD  1 
ATOM   47    N  NE  . ARG A 1 70  ? 121.317 104.668 68.095  1.00 85.91  ? 17  ARG D NE  1 
ATOM   48    C  CZ  . ARG A 1 70  ? 121.129 103.372 68.298  1.00 83.16  ? 17  ARG D CZ  1 
ATOM   49    N  NH1 . ARG A 1 70  ? 120.019 102.914 68.853  1.00 78.47  ? 17  ARG D NH1 1 
ATOM   50    N  NH2 . ARG A 1 70  ? 122.077 102.515 67.936  1.00 80.81  ? 17  ARG D NH2 1 
ATOM   51    N  N   . ILE A 1 71  ? 117.875 107.260 73.217  1.00 57.11  ? 18  ILE D N   1 
ATOM   52    C  CA  . ILE A 1 71  ? 116.595 107.565 73.853  1.00 55.93  ? 18  ILE D CA  1 
ATOM   53    C  C   . ILE A 1 71  ? 116.698 108.833 74.692  1.00 56.10  ? 18  ILE D C   1 
ATOM   54    O  O   . ILE A 1 71  ? 115.843 109.722 74.611  1.00 60.68  ? 18  ILE D O   1 
ATOM   55    C  CB  . ILE A 1 71  ? 116.118 106.370 74.693  1.00 54.96  ? 18  ILE D CB  1 
ATOM   56    C  CG1 . ILE A 1 71  ? 115.633 105.245 73.782  1.00 57.40  ? 18  ILE D CG1 1 
ATOM   57    C  CG2 . ILE A 1 71  ? 115.028 106.795 75.646  1.00 54.47  ? 18  ILE D CG2 1 
ATOM   58    C  CD1 . ILE A 1 71  ? 115.308 103.976 74.511  1.00 59.41  ? 18  ILE D CD1 1 
ATOM   59    N  N   . LEU A 1 72  ? 117.746 108.939 75.511  1.00 52.44  ? 19  LEU D N   1 
ATOM   60    C  CA  . LEU A 1 72  ? 117.898 110.126 76.346  1.00 51.49  ? 19  LEU D CA  1 
ATOM   61    C  C   . LEU A 1 72  ? 118.120 111.375 75.505  1.00 53.55  ? 19  LEU D C   1 
ATOM   62    O  O   . LEU A 1 72  ? 117.566 112.440 75.807  1.00 57.01  ? 19  LEU D O   1 
ATOM   63    C  CB  . LEU A 1 72  ? 119.048 109.936 77.330  1.00 52.49  ? 19  LEU D CB  1 
ATOM   64    C  CG  . LEU A 1 72  ? 118.861 108.856 78.390  1.00 49.33  ? 19  LEU D CG  1 
ATOM   65    C  CD1 . LEU A 1 72  ? 120.061 108.806 79.306  1.00 45.95  ? 19  LEU D CD1 1 
ATOM   66    C  CD2 . LEU A 1 72  ? 117.604 109.116 79.178  1.00 47.72  ? 19  LEU D CD2 1 
ATOM   67    N  N   . ASP A 1 73  ? 118.931 111.271 74.450  1.00 55.94  ? 20  ASP D N   1 
ATOM   68    C  CA  . ASP A 1 73  ? 119.168 112.426 73.592  1.00 58.89  ? 20  ASP D CA  1 
ATOM   69    C  C   . ASP A 1 73  ? 117.884 112.881 72.917  1.00 58.14  ? 20  ASP D C   1 
ATOM   70    O  O   . ASP A 1 73  ? 117.644 114.084 72.774  1.00 61.67  ? 20  ASP D O   1 
ATOM   71    C  CB  . ASP A 1 73  ? 120.234 112.102 72.550  1.00 65.05  ? 20  ASP D CB  1 
ATOM   72    C  CG  . ASP A 1 73  ? 121.598 111.885 73.163  1.00 70.62  ? 20  ASP D CG  1 
ATOM   73    O  OD1 . ASP A 1 73  ? 121.717 112.001 74.398  1.00 70.01  ? 20  ASP D OD1 1 
ATOM   74    O  OD2 . ASP A 1 73  ? 122.552 111.599 72.413  1.00 71.70  ? 20  ASP D OD2 1 
ATOM   75    N  N   . ARG A 1 74  ? 117.053 111.935 72.481  1.00 55.79  ? 21  ARG D N   1 
ATOM   76    C  CA  . ARG A 1 74  ? 115.766 112.309 71.910  1.00 56.78  ? 21  ARG D CA  1 
ATOM   77    C  C   . ARG A 1 74  ? 114.865 112.955 72.954  1.00 59.77  ? 21  ARG D C   1 
ATOM   78    O  O   . ARG A 1 74  ? 114.132 113.901 72.647  1.00 60.49  ? 21  ARG D O   1 
ATOM   79    C  CB  . ARG A 1 74  ? 115.084 111.091 71.296  1.00 56.61  ? 21  ARG D CB  1 
ATOM   80    C  CG  . ARG A 1 74  ? 113.796 111.430 70.579  1.00 61.01  ? 21  ARG D CG  1 
ATOM   81    C  CD  . ARG A 1 74  ? 112.989 110.191 70.277  1.00 61.44  ? 21  ARG D CD  1 
ATOM   82    N  NE  . ARG A 1 74  ? 112.821 109.355 71.459  1.00 68.03  ? 21  ARG D NE  1 
ATOM   83    C  CZ  . ARG A 1 74  ? 111.925 109.572 72.412  1.00 69.66  ? 21  ARG D CZ  1 
ATOM   84    N  NH1 . ARG A 1 74  ? 111.104 110.607 72.367  1.00 72.99  ? 21  ARG D NH1 1 
ATOM   85    N  NH2 . ARG A 1 74  ? 111.850 108.727 73.436  1.00 65.10  ? 21  ARG D NH2 1 
ATOM   86    N  N   . LEU A 1 75  ? 114.892 112.452 74.189  1.00 58.66  ? 22  LEU D N   1 
ATOM   87    C  CA  . LEU A 1 75  ? 114.061 113.041 75.235  1.00 50.97  ? 22  LEU D CA  1 
ATOM   88    C  C   . LEU A 1 75  ? 114.455 114.484 75.512  1.00 54.58  ? 22  LEU D C   1 
ATOM   89    O  O   . LEU A 1 75  ? 113.589 115.354 75.638  1.00 63.38  ? 22  LEU D O   1 
ATOM   90    C  CB  . LEU A 1 75  ? 114.147 112.218 76.517  1.00 50.99  ? 22  LEU D CB  1 
ATOM   91    C  CG  . LEU A 1 75  ? 113.497 110.841 76.502  1.00 55.46  ? 22  LEU D CG  1 
ATOM   92    C  CD1 . LEU A 1 75  ? 113.475 110.266 77.903  1.00 51.73  ? 22  LEU D CD1 1 
ATOM   93    C  CD2 . LEU A 1 75  ? 112.102 110.922 75.924  1.00 55.06  ? 22  LEU D CD2 1 
ATOM   94    N  N   . LEU A 1 76  ? 115.752 114.765 75.592  1.00 53.88  ? 23  LEU D N   1 
ATOM   95    C  CA  . LEU A 1 76  ? 116.197 116.109 75.939  1.00 53.77  ? 23  LEU D CA  1 
ATOM   96    C  C   . LEU A 1 76  ? 116.319 117.036 74.736  1.00 57.73  ? 23  LEU D C   1 
ATOM   97    O  O   . LEU A 1 76  ? 116.726 118.189 74.903  1.00 59.49  ? 23  LEU D O   1 
ATOM   98    C  CB  . LEU A 1 76  ? 117.530 116.048 76.682  1.00 50.97  ? 23  LEU D CB  1 
ATOM   99    C  CG  . LEU A 1 76  ? 117.475 115.258 77.989  1.00 51.07  ? 23  LEU D CG  1 
ATOM   100   C  CD1 . LEU A 1 76  ? 118.791 115.355 78.733  1.00 50.70  ? 23  LEU D CD1 1 
ATOM   101   C  CD2 . LEU A 1 76  ? 116.328 115.730 78.860  1.00 46.29  ? 23  LEU D CD2 1 
ATOM   102   N  N   . ASP A 1 77  ? 115.970 116.574 73.540  1.00 61.22  ? 24  ASP D N   1 
ATOM   103   C  CA  . ASP A 1 77  ? 116.052 117.404 72.344  1.00 63.11  ? 24  ASP D CA  1 
ATOM   104   C  C   . ASP A 1 77  ? 114.804 118.271 72.233  1.00 65.05  ? 24  ASP D C   1 
ATOM   105   O  O   . ASP A 1 77  ? 113.697 117.755 72.057  1.00 63.99  ? 24  ASP D O   1 
ATOM   106   C  CB  . ASP A 1 77  ? 116.209 116.523 71.107  1.00 68.77  ? 24  ASP D CB  1 
ATOM   107   C  CG  . ASP A 1 77  ? 116.455 117.322 69.845  1.00 81.93  ? 24  ASP D CG  1 
ATOM   108   O  OD1 . ASP A 1 77  ? 116.708 118.540 69.941  1.00 82.94  ? 24  ASP D OD1 1 
ATOM   109   O  OD2 . ASP A 1 77  ? 116.393 116.727 68.750  1.00 87.86  ? 24  ASP D OD2 1 
ATOM   110   N  N   . GLY A 1 78  ? 114.985 119.586 72.312  1.00 66.78  ? 25  GLY D N   1 
ATOM   111   C  CA  . GLY A 1 78  ? 113.856 120.494 72.300  1.00 63.43  ? 25  GLY D CA  1 
ATOM   112   C  C   . GLY A 1 78  ? 113.083 120.559 73.596  1.00 62.83  ? 25  GLY D C   1 
ATOM   113   O  O   . GLY A 1 78  ? 111.925 120.983 73.592  1.00 67.64  ? 25  GLY D O   1 
ATOM   114   N  N   . TYR A 1 79  ? 113.689 120.149 74.704  1.00 59.96  ? 26  TYR D N   1 
ATOM   115   C  CA  . TYR A 1 79  ? 113.043 120.137 76.009  1.00 54.79  ? 26  TYR D CA  1 
ATOM   116   C  C   . TYR A 1 79  ? 113.426 121.400 76.765  1.00 58.57  ? 26  TYR D C   1 
ATOM   117   O  O   . TYR A 1 79  ? 114.612 121.725 76.876  1.00 61.62  ? 26  TYR D O   1 
ATOM   118   C  CB  . TYR A 1 79  ? 113.463 118.893 76.793  1.00 52.72  ? 26  TYR D CB  1 
ATOM   119   C  CG  . TYR A 1 79  ? 112.808 118.725 78.143  1.00 49.12  ? 26  TYR D CG  1 
ATOM   120   C  CD1 . TYR A 1 79  ? 113.312 119.359 79.263  1.00 46.88  ? 26  TYR D CD1 1 
ATOM   121   C  CD2 . TYR A 1 79  ? 111.706 117.904 78.300  1.00 46.59  ? 26  TYR D CD2 1 
ATOM   122   C  CE1 . TYR A 1 79  ? 112.729 119.201 80.490  1.00 43.60  ? 26  TYR D CE1 1 
ATOM   123   C  CE2 . TYR A 1 79  ? 111.118 117.741 79.529  1.00 45.80  ? 26  TYR D CE2 1 
ATOM   124   C  CZ  . TYR A 1 79  ? 111.633 118.395 80.619  1.00 43.66  ? 26  TYR D CZ  1 
ATOM   125   O  OH  . TYR A 1 79  ? 111.056 118.239 81.852  1.00 45.76  ? 26  TYR D OH  1 
ATOM   126   N  N   . ASP A 1 80  ? 112.427 122.109 77.277  1.00 56.00  ? 27  ASP D N   1 
ATOM   127   C  CA  . ASP A 1 80  ? 112.638 123.328 78.045  1.00 53.60  ? 27  ASP D CA  1 
ATOM   128   C  C   . ASP A 1 80  ? 112.313 123.048 79.504  1.00 49.73  ? 27  ASP D C   1 
ATOM   129   O  O   . ASP A 1 80  ? 111.161 122.762 79.840  1.00 48.29  ? 27  ASP D O   1 
ATOM   130   C  CB  . ASP A 1 80  ? 111.774 124.470 77.517  1.00 57.35  ? 27  ASP D CB  1 
ATOM   131   C  CG  . ASP A 1 80  ? 112.177 125.813 78.088  1.00 60.33  ? 27  ASP D CG  1 
ATOM   132   O  OD1 . ASP A 1 80  ? 113.229 125.883 78.750  1.00 60.22  ? 27  ASP D OD1 1 
ATOM   133   O  OD2 . ASP A 1 80  ? 111.445 126.798 77.876  1.00 60.78  ? 27  ASP D OD2 1 
ATOM   134   N  N   . ASN A 1 81  ? 113.322 123.133 80.363  1.00 49.97  ? 28  ASN D N   1 
ATOM   135   C  CA  . ASN A 1 81  ? 113.147 122.865 81.782  1.00 46.91  ? 28  ASN D CA  1 
ATOM   136   C  C   . ASN A 1 81  ? 112.672 124.081 82.562  1.00 47.14  ? 28  ASN D C   1 
ATOM   137   O  O   . ASN A 1 81  ? 112.523 123.993 83.782  1.00 50.11  ? 28  ASN D O   1 
ATOM   138   C  CB  . ASN A 1 81  ? 114.449 122.335 82.390  1.00 44.55  ? 28  ASN D CB  1 
ATOM   139   C  CG  . ASN A 1 81  ? 115.617 123.266 82.179  1.00 51.22  ? 28  ASN D CG  1 
ATOM   140   O  OD1 . ASN A 1 81  ? 115.445 124.443 81.882  1.00 55.92  ? 28  ASN D OD1 1 
ATOM   141   N  ND2 . ASN A 1 81  ? 116.820 122.741 82.335  1.00 51.49  ? 28  ASN D ND2 1 
ATOM   142   N  N   . ARG A 1 82  ? 112.452 125.211 81.898  1.00 45.14  ? 29  ARG D N   1 
ATOM   143   C  CA  . ARG A 1 82  ? 111.887 126.384 82.548  1.00 43.49  ? 29  ARG D CA  1 
ATOM   144   C  C   . ARG A 1 82  ? 110.369 126.359 82.593  1.00 45.92  ? 29  ARG D C   1 
ATOM   145   O  O   . ARG A 1 82  ? 109.769 127.247 83.203  1.00 47.04  ? 29  ARG D O   1 
ATOM   146   C  CB  . ARG A 1 82  ? 112.344 127.658 81.833  1.00 43.16  ? 29  ARG D CB  1 
ATOM   147   C  CG  . ARG A 1 82  ? 113.840 127.816 81.754  1.00 47.19  ? 29  ARG D CG  1 
ATOM   148   C  CD  . ARG A 1 82  ? 114.229 128.920 80.788  1.00 49.41  ? 29  ARG D CD  1 
ATOM   149   N  NE  . ARG A 1 82  ? 113.741 128.666 79.440  1.00 55.91  ? 29  ARG D NE  1 
ATOM   150   C  CZ  . ARG A 1 82  ? 114.183 129.284 78.354  1.00 59.08  ? 29  ARG D CZ  1 
ATOM   151   N  NH1 . ARG A 1 82  ? 115.143 130.191 78.419  1.00 57.69  ? 29  ARG D NH1 1 
ATOM   152   N  NH2 . ARG A 1 82  ? 113.655 128.979 77.173  1.00 56.45  ? 29  ARG D NH2 1 
ATOM   153   N  N   . LEU A 1 83  ? 109.739 125.370 81.968  1.00 45.88  ? 30  LEU D N   1 
ATOM   154   C  CA  . LEU A 1 83  ? 108.290 125.288 81.875  1.00 39.89  ? 30  LEU D CA  1 
ATOM   155   C  C   . LEU A 1 83  ? 107.808 124.009 82.539  1.00 40.00  ? 30  LEU D C   1 
ATOM   156   O  O   . LEU A 1 83  ? 108.312 122.925 82.240  1.00 42.59  ? 30  LEU D O   1 
ATOM   157   C  CB  . LEU A 1 83  ? 107.842 125.332 80.415  1.00 42.34  ? 30  LEU D CB  1 
ATOM   158   C  CG  . LEU A 1 83  ? 108.358 126.528 79.621  1.00 39.89  ? 30  LEU D CG  1 
ATOM   159   C  CD1 . LEU A 1 83  ? 107.868 126.469 78.202  1.00 38.20  ? 30  LEU D CD1 1 
ATOM   160   C  CD2 . LEU A 1 83  ? 107.935 127.822 80.276  1.00 35.99  ? 30  LEU D CD2 1 
ATOM   161   N  N   . ARG A 1 84  ? 106.830 124.140 83.430  1.00 41.36  ? 31  ARG D N   1 
ATOM   162   C  CA  . ARG A 1 84  ? 106.258 122.992 84.106  1.00 38.54  ? 31  ARG D CA  1 
ATOM   163   C  C   . ARG A 1 84  ? 105.424 122.168 83.131  1.00 41.54  ? 31  ARG D C   1 
ATOM   164   O  O   . ARG A 1 84  ? 104.968 122.677 82.108  1.00 45.39  ? 31  ARG D O   1 
ATOM   165   C  CB  . ARG A 1 84  ? 105.395 123.449 85.276  1.00 34.63  ? 31  ARG D CB  1 
ATOM   166   C  CG  . ARG A 1 84  ? 104.202 124.249 84.853  1.00 40.38  ? 31  ARG D CG  1 
ATOM   167   C  CD  . ARG A 1 84  ? 103.295 124.556 86.014  1.00 40.69  ? 31  ARG D CD  1 
ATOM   168   N  NE  . ARG A 1 84  ? 102.073 125.196 85.554  1.00 46.16  ? 31  ARG D NE  1 
ATOM   169   C  CZ  . ARG A 1 84  ? 100.978 124.538 85.207  1.00 46.29  ? 31  ARG D CZ  1 
ATOM   170   N  NH1 . ARG A 1 84  ? 100.910 123.222 85.286  1.00 45.03  ? 31  ARG D NH1 1 
ATOM   171   N  NH2 . ARG A 1 84  ? 99.926  125.219 84.764  1.00 45.53  ? 31  ARG D NH2 1 
ATOM   172   N  N   . PRO A 1 85  ? 105.238 120.880 83.413  1.00 41.59  ? 32  PRO D N   1 
ATOM   173   C  CA  . PRO A 1 85  ? 104.405 120.052 82.537  1.00 44.39  ? 32  PRO D CA  1 
ATOM   174   C  C   . PRO A 1 85  ? 102.980 120.570 82.476  1.00 52.53  ? 32  PRO D C   1 
ATOM   175   O  O   . PRO A 1 85  ? 102.396 120.959 83.487  1.00 51.85  ? 32  PRO D O   1 
ATOM   176   C  CB  . PRO A 1 85  ? 104.465 118.671 83.193  1.00 45.31  ? 32  PRO D CB  1 
ATOM   177   C  CG  . PRO A 1 85  ? 105.674 118.703 84.040  1.00 42.93  ? 32  PRO D CG  1 
ATOM   178   C  CD  . PRO A 1 85  ? 105.819 120.097 84.512  1.00 38.55  ? 32  PRO D CD  1 
ATOM   179   N  N   . GLY A 1 86  ? 102.417 120.554 81.274  1.00 56.63  ? 33  GLY D N   1 
ATOM   180   C  CA  . GLY A 1 86  ? 101.054 121.019 81.086  1.00 54.54  ? 33  GLY D CA  1 
ATOM   181   C  C   . GLY A 1 86  ? 100.845 122.473 81.445  1.00 55.33  ? 33  GLY D C   1 
ATOM   182   O  O   . GLY A 1 86  ? 99.778  122.834 81.953  1.00 58.82  ? 33  GLY D O   1 
ATOM   183   N  N   . LEU A 1 87  ? 101.836 123.320 81.188  1.00 52.64  ? 34  LEU D N   1 
ATOM   184   C  CA  . LEU A 1 87  ? 101.687 124.739 81.472  1.00 51.32  ? 34  LEU D CA  1 
ATOM   185   C  C   . LEU A 1 87  ? 100.673 125.357 80.521  1.00 59.15  ? 34  LEU D C   1 
ATOM   186   O  O   . LEU A 1 87  ? 100.793 125.232 79.300  1.00 58.82  ? 34  LEU D O   1 
ATOM   187   C  CB  . LEU A 1 87  ? 103.028 125.456 81.351  1.00 46.23  ? 34  LEU D CB  1 
ATOM   188   C  CG  . LEU A 1 87  ? 102.974 126.983 81.312  1.00 44.47  ? 34  LEU D CG  1 
ATOM   189   C  CD1 . LEU A 1 87  ? 102.301 127.536 82.547  1.00 53.10  ? 34  LEU D CD1 1 
ATOM   190   C  CD2 . LEU A 1 87  ? 104.363 127.555 81.178  1.00 38.76  ? 34  LEU D CD2 1 
ATOM   191   N  N   . GLY A 1 88  ? 99.676  126.029 81.086  1.00 60.39  ? 35  GLY D N   1 
ATOM   192   C  CA  . GLY A 1 88  ? 98.621  126.625 80.303  1.00 59.80  ? 35  GLY D CA  1 
ATOM   193   C  C   . GLY A 1 88  ? 97.573  125.656 79.813  1.00 68.82  ? 35  GLY D C   1 
ATOM   194   O  O   . GLY A 1 88  ? 96.679  126.067 79.065  1.00 73.96  ? 35  GLY D O   1 
ATOM   195   N  N   . GLU A 1 89  ? 97.655  124.394 80.198  1.00 67.03  ? 36  GLU D N   1 
ATOM   196   C  CA  . GLU A 1 89  ? 96.714  123.374 79.753  1.00 66.59  ? 36  GLU D CA  1 
ATOM   197   C  C   . GLU A 1 89  ? 96.122  122.563 80.896  1.00 65.79  ? 36  GLU D C   1 
ATOM   198   O  O   . GLU A 1 89  ? 94.949  122.194 80.831  1.00 66.98  ? 36  GLU D O   1 
ATOM   199   C  CB  . GLU A 1 89  ? 97.411  122.447 78.749  1.00 70.31  ? 36  GLU D CB  1 
ATOM   200   C  CG  . GLU A 1 89  ? 96.505  121.412 78.114  1.00 81.82  ? 36  GLU D CG  1 
ATOM   201   C  CD  . GLU A 1 89  ? 97.231  120.551 77.101  1.00 95.14  ? 36  GLU D CD  1 
ATOM   202   O  OE1 . GLU A 1 89  ? 98.471  120.439 77.195  1.00 95.94  ? 36  GLU D OE1 1 
ATOM   203   O  OE2 . GLU A 1 89  ? 96.564  119.992 76.205  1.00 104.90 ? 36  GLU D OE2 1 
ATOM   204   N  N   . ARG A 1 90  ? 96.896  122.275 81.938  1.00 61.57  ? 37  ARG D N   1 
ATOM   205   C  CA  . ARG A 1 90  ? 96.400  121.501 83.070  1.00 58.19  ? 37  ARG D CA  1 
ATOM   206   C  C   . ARG A 1 90  ? 97.193  121.888 84.312  1.00 53.55  ? 37  ARG D C   1 
ATOM   207   O  O   . ARG A 1 90  ? 98.025  122.799 84.281  1.00 57.02  ? 37  ARG D O   1 
ATOM   208   C  CB  . ARG A 1 90  ? 96.486  119.997 82.785  1.00 60.31  ? 37  ARG D CB  1 
ATOM   209   C  CG  . ARG A 1 90  ? 97.892  119.482 82.549  1.00 61.57  ? 37  ARG D CG  1 
ATOM   210   C  CD  . ARG A 1 90  ? 97.923  117.965 82.549  1.00 63.97  ? 37  ARG D CD  1 
ATOM   211   N  NE  . ARG A 1 90  ? 99.231  117.432 82.188  1.00 74.20  ? 37  ARG D NE  1 
ATOM   212   C  CZ  . ARG A 1 90  ? 100.240 117.273 83.034  1.00 68.34  ? 37  ARG D CZ  1 
ATOM   213   N  NH1 . ARG A 1 90  ? 100.147 117.645 84.301  1.00 61.20  ? 37  ARG D NH1 1 
ATOM   214   N  NH2 . ARG A 1 90  ? 101.371 116.725 82.600  1.00 59.76  ? 37  ARG D NH2 1 
ATOM   215   N  N   . VAL A 1 91  ? 96.935  121.187 85.411  1.00 49.26  ? 38  VAL D N   1 
ATOM   216   C  CA  . VAL A 1 91  ? 97.602  121.415 86.687  1.00 46.98  ? 38  VAL D CA  1 
ATOM   217   C  C   . VAL A 1 91  ? 98.575  120.270 86.925  1.00 52.99  ? 38  VAL D C   1 
ATOM   218   O  O   . VAL A 1 91  ? 98.218  119.100 86.751  1.00 59.03  ? 38  VAL D O   1 
ATOM   219   C  CB  . VAL A 1 91  ? 96.589  121.521 87.840  1.00 43.54  ? 38  VAL D CB  1 
ATOM   220   C  CG1 . VAL A 1 91  ? 97.291  121.505 89.179  1.00 42.28  ? 38  VAL D CG1 1 
ATOM   221   C  CG2 . VAL A 1 91  ? 95.768  122.781 87.706  1.00 45.94  ? 38  VAL D CG2 1 
ATOM   222   N  N   . THR A 1 92  ? 99.801  120.603 87.310  1.00 48.46  ? 39  THR D N   1 
ATOM   223   C  CA  . THR A 1 92  ? 100.772 119.582 87.680  1.00 45.68  ? 39  THR D CA  1 
ATOM   224   C  C   . THR A 1 92  ? 100.434 119.034 89.059  1.00 48.00  ? 39  THR D C   1 
ATOM   225   O  O   . THR A 1 92  ? 100.335 119.794 90.025  1.00 48.24  ? 39  THR D O   1 
ATOM   226   C  CB  . THR A 1 92  ? 102.182 120.162 87.671  1.00 42.35  ? 39  THR D CB  1 
ATOM   227   O  OG1 . THR A 1 92  ? 102.487 120.656 86.365  1.00 50.17  ? 39  THR D OG1 1 
ATOM   228   C  CG2 . THR A 1 92  ? 103.187 119.095 88.035  1.00 39.76  ? 39  THR D CG2 1 
ATOM   229   N  N   . GLU A 1 93  ? 100.264 117.720 89.157  1.00 49.21  ? 40  GLU D N   1 
ATOM   230   C  CA  . GLU A 1 93  ? 99.941  117.058 90.414  1.00 46.99  ? 40  GLU D CA  1 
ATOM   231   C  C   . GLU A 1 93  ? 101.174 116.316 90.898  1.00 42.44  ? 40  GLU D C   1 
ATOM   232   O  O   . GLU A 1 93  ? 101.676 115.427 90.206  1.00 43.90  ? 40  GLU D O   1 
ATOM   233   C  CB  . GLU A 1 93  ? 98.770  116.094 90.249  1.00 56.53  ? 40  GLU D CB  1 
ATOM   234   C  CG  . GLU A 1 93  ? 97.598  116.672 89.488  1.00 67.62  ? 40  GLU D CG  1 
ATOM   235   C  CD  . GLU A 1 93  ? 96.501  115.659 89.259  1.00 81.28  ? 40  GLU D CD  1 
ATOM   236   O  OE1 . GLU A 1 93  ? 96.577  114.560 89.846  1.00 81.83  ? 40  GLU D OE1 1 
ATOM   237   O  OE2 . GLU A 1 93  ? 95.566  115.962 88.488  1.00 88.94  ? 40  GLU D OE2 1 
ATOM   238   N  N   . VAL A 1 94  ? 101.641 116.664 92.090  1.00 38.22  ? 41  VAL D N   1 
ATOM   239   C  CA  . VAL A 1 94  ? 102.836 116.078 92.677  1.00 33.50  ? 41  VAL D CA  1 
ATOM   240   C  C   . VAL A 1 94  ? 102.396 115.217 93.848  1.00 34.81  ? 41  VAL D C   1 
ATOM   241   O  O   . VAL A 1 94  ? 101.682 115.688 94.738  1.00 39.14  ? 41  VAL D O   1 
ATOM   242   C  CB  . VAL A 1 94  ? 103.831 117.162 93.117  1.00 29.66  ? 41  VAL D CB  1 
ATOM   243   C  CG1 . VAL A 1 94  ? 105.094 116.541 93.663  1.00 28.57  ? 41  VAL D CG1 1 
ATOM   244   C  CG2 . VAL A 1 94  ? 104.154 118.069 91.958  1.00 30.72  ? 41  VAL D CG2 1 
ATOM   245   N  N   . LYS A 1 95  ? 102.796 113.952 93.837  1.00 32.99  ? 42  LYS D N   1 
ATOM   246   C  CA  . LYS A 1 95  ? 102.498 113.027 94.920  1.00 32.45  ? 42  LYS D CA  1 
ATOM   247   C  C   . LYS A 1 95  ? 103.741 112.881 95.781  1.00 33.58  ? 42  LYS D C   1 
ATOM   248   O  O   . LYS A 1 95  ? 104.808 112.529 95.276  1.00 36.87  ? 42  LYS D O   1 
ATOM   249   C  CB  . LYS A 1 95  ? 102.048 111.673 94.376  1.00 34.22  ? 42  LYS D CB  1 
ATOM   250   C  CG  . LYS A 1 95  ? 100.661 111.693 93.784  1.00 38.84  ? 42  LYS D CG  1 
ATOM   251   C  CD  . LYS A 1 95  ? 100.116 110.300 93.588  1.00 51.66  ? 42  LYS D CD  1 
ATOM   252   C  CE  . LYS A 1 95  ? 98.686  110.356 93.088  1.00 61.71  ? 42  LYS D CE  1 
ATOM   253   N  NZ  . LYS A 1 95  ? 98.140  109.007 92.802  1.00 67.90  ? 42  LYS D NZ  1 
ATOM   254   N  N   . THR A 1 96  ? 103.603 113.149 97.074  1.00 34.12  ? 43  THR D N   1 
ATOM   255   C  CA  . THR A 1 96  ? 104.734 113.217 97.980  1.00 33.98  ? 43  THR D CA  1 
ATOM   256   C  C   . THR A 1 96  ? 104.587 112.203 99.104  1.00 34.63  ? 43  THR D C   1 
ATOM   257   O  O   . THR A 1 96  ? 103.491 111.726 99.404  1.00 37.93  ? 43  THR D O   1 
ATOM   258   C  CB  . THR A 1 96  ? 104.885 114.618 98.583  1.00 34.31  ? 43  THR D CB  1 
ATOM   259   O  OG1 . THR A 1 96  ? 103.700 114.959 99.305  1.00 37.55  ? 43  THR D OG1 1 
ATOM   260   C  CG2 . THR A 1 96  ? 105.099 115.638 97.499  1.00 37.83  ? 43  THR D CG2 1 
ATOM   261   N  N   . ASP A 1 97  ? 105.725 111.854 99.699  1.00 34.92  ? 44  ASP D N   1 
ATOM   262   C  CA  . ASP A 1 97  ? 105.721 111.136 100.968 1.00 32.51  ? 44  ASP D CA  1 
ATOM   263   C  C   . ASP A 1 97  ? 107.068 111.312 101.654 1.00 30.96  ? 44  ASP D C   1 
ATOM   264   O  O   . ASP A 1 97  ? 108.046 111.769 101.057 1.00 32.77  ? 44  ASP D O   1 
ATOM   265   C  CB  . ASP A 1 97  ? 105.379 109.655 100.793 1.00 36.31  ? 44  ASP D CB  1 
ATOM   266   C  CG  . ASP A 1 97  ? 106.326 108.943 99.880  1.00 45.17  ? 44  ASP D CG  1 
ATOM   267   O  OD1 . ASP A 1 97  ? 106.471 109.383 98.724  1.00 49.19  ? 44  ASP D OD1 1 
ATOM   268   O  OD2 . ASP A 1 97  ? 106.920 107.938 100.316 1.00 47.59  ? 44  ASP D OD2 1 
ATOM   269   N  N   . ILE A 1 98  ? 107.095 110.957 102.935 1.00 31.27  ? 45  ILE D N   1 
ATOM   270   C  CA  . ILE A 1 98  ? 108.244 111.188 103.798 1.00 27.50  ? 45  ILE D CA  1 
ATOM   271   C  C   . ILE A 1 98  ? 108.574 109.904 104.544 1.00 29.06  ? 45  ILE D C   1 
ATOM   272   O  O   . ILE A 1 98  ? 107.688 109.271 105.131 1.00 34.82  ? 45  ILE D O   1 
ATOM   273   C  CB  . ILE A 1 98  ? 107.981 112.336 104.787 1.00 26.47  ? 45  ILE D CB  1 
ATOM   274   C  CG1 . ILE A 1 98  ? 107.656 113.622 104.040 1.00 24.96  ? 45  ILE D CG1 1 
ATOM   275   C  CG2 . ILE A 1 98  ? 109.182 112.576 105.652 1.00 25.04  ? 45  ILE D CG2 1 
ATOM   276   C  CD1 . ILE A 1 98  ? 107.407 114.788 104.942 1.00 27.02  ? 45  ILE D CD1 1 
ATOM   277   N  N   . PHE A 1 99  ? 109.847 109.524 104.529 1.00 27.05  ? 46  PHE D N   1 
ATOM   278   C  CA  . PHE A 1 99  ? 110.351 108.450 105.378 1.00 24.85  ? 46  PHE D CA  1 
ATOM   279   C  C   . PHE A 1 99  ? 111.353 109.059 106.350 1.00 25.89  ? 46  PHE D C   1 
ATOM   280   O  O   . PHE A 1 99  ? 112.475 109.384 105.966 1.00 28.86  ? 46  PHE D O   1 
ATOM   281   C  CB  . PHE A 1 99  ? 110.984 107.338 104.556 1.00 24.70  ? 46  PHE D CB  1 
ATOM   282   C  CG  . PHE A 1 99  ? 111.478 106.192 105.381 1.00 29.88  ? 46  PHE D CG  1 
ATOM   283   C  CD1 . PHE A 1 99  ? 110.600 105.251 105.869 1.00 32.12  ? 46  PHE D CD1 1 
ATOM   284   C  CD2 . PHE A 1 99  ? 112.817 106.056 105.673 1.00 31.18  ? 46  PHE D CD2 1 
ATOM   285   C  CE1 . PHE A 1 99  ? 111.050 104.199 106.629 1.00 31.30  ? 46  PHE D CE1 1 
ATOM   286   C  CE2 . PHE A 1 99  ? 113.266 105.008 106.435 1.00 30.78  ? 46  PHE D CE2 1 
ATOM   287   C  CZ  . PHE A 1 99  ? 112.381 104.080 106.909 1.00 30.96  ? 46  PHE D CZ  1 
ATOM   288   N  N   . VAL A 1 100 ? 110.946 109.208 107.604 1.00 26.41  ? 47  VAL D N   1 
ATOM   289   C  CA  . VAL A 1 100 ? 111.774 109.818 108.636 1.00 28.08  ? 47  VAL D CA  1 
ATOM   290   C  C   . VAL A 1 100 ? 112.764 108.772 109.136 1.00 32.94  ? 47  VAL D C   1 
ATOM   291   O  O   . VAL A 1 100 ? 112.386 107.844 109.850 1.00 38.00  ? 47  VAL D O   1 
ATOM   292   C  CB  . VAL A 1 100 ? 110.916 110.357 109.783 1.00 25.66  ? 47  VAL D CB  1 
ATOM   293   C  CG1 . VAL A 1 100 ? 111.777 111.045 110.804 1.00 27.73  ? 47  VAL D CG1 1 
ATOM   294   C  CG2 . VAL A 1 100 ? 109.856 111.300 109.250 1.00 26.24  ? 47  VAL D CG2 1 
ATOM   295   N  N   . THR A 1 101 ? 114.037 108.918 108.771 1.00 32.89  ? 48  THR D N   1 
ATOM   296   C  CA  . THR A 1 101 ? 115.021 107.929 109.189 1.00 32.08  ? 48  THR D CA  1 
ATOM   297   C  C   . THR A 1 101 ? 115.507 108.150 110.613 1.00 35.20  ? 48  THR D C   1 
ATOM   298   O  O   . THR A 1 101 ? 116.075 107.229 111.205 1.00 38.42  ? 48  THR D O   1 
ATOM   299   C  CB  . THR A 1 101 ? 116.215 107.915 108.231 1.00 32.62  ? 48  THR D CB  1 
ATOM   300   O  OG1 . THR A 1 101 ? 116.910 109.162 108.305 1.00 34.83  ? 48  THR D OG1 1 
ATOM   301   C  CG2 . THR A 1 101 ? 115.744 107.695 106.814 1.00 26.27  ? 48  THR D CG2 1 
ATOM   302   N  N   . SER A 1 102 ? 115.309 109.345 111.165 1.00 32.52  ? 49  SER D N   1 
ATOM   303   C  CA  . SER A 1 102 ? 115.621 109.619 112.562 1.00 35.83  ? 49  SER D CA  1 
ATOM   304   C  C   . SER A 1 102 ? 114.966 110.930 112.956 1.00 35.18  ? 49  SER D C   1 
ATOM   305   O  O   . SER A 1 102 ? 115.181 111.947 112.297 1.00 35.48  ? 49  SER D O   1 
ATOM   306   C  CB  . SER A 1 102 ? 117.125 109.703 112.794 1.00 37.70  ? 49  SER D CB  1 
ATOM   307   O  OG  . SER A 1 102 ? 117.634 110.923 112.296 1.00 40.16  ? 49  SER D OG  1 
ATOM   308   N  N   . PHE A 1 103 ? 114.179 110.907 114.026 1.00 35.10  ? 50  PHE D N   1 
ATOM   309   C  CA  . PHE A 1 103 ? 113.570 112.116 114.562 1.00 32.73  ? 50  PHE D CA  1 
ATOM   310   C  C   . PHE A 1 103 ? 114.512 112.698 115.606 1.00 32.37  ? 50  PHE D C   1 
ATOM   311   O  O   . PHE A 1 103 ? 114.609 112.181 116.719 1.00 35.00  ? 50  PHE D O   1 
ATOM   312   C  CB  . PHE A 1 103 ? 112.200 111.820 115.157 1.00 30.34  ? 50  PHE D CB  1 
ATOM   313   C  CG  . PHE A 1 103 ? 111.429 113.046 115.522 1.00 29.67  ? 50  PHE D CG  1 
ATOM   314   C  CD1 . PHE A 1 103 ? 110.688 113.717 114.579 1.00 32.26  ? 50  PHE D CD1 1 
ATOM   315   C  CD2 . PHE A 1 103 ? 111.447 113.530 116.809 1.00 30.93  ? 50  PHE D CD2 1 
ATOM   316   C  CE1 . PHE A 1 103 ? 109.984 114.846 114.917 1.00 32.42  ? 50  PHE D CE1 1 
ATOM   317   C  CE2 . PHE A 1 103 ? 110.739 114.656 117.146 1.00 31.04  ? 50  PHE D CE2 1 
ATOM   318   C  CZ  . PHE A 1 103 ? 110.010 115.313 116.201 1.00 31.99  ? 50  PHE D CZ  1 
ATOM   319   N  N   . GLY A 1 104 ? 115.193 113.779 115.248 1.00 31.13  ? 51  GLY D N   1 
ATOM   320   C  CA  . GLY A 1 104 ? 116.297 114.267 116.032 1.00 27.33  ? 51  GLY D CA  1 
ATOM   321   C  C   . GLY A 1 104 ? 115.848 114.977 117.279 1.00 29.39  ? 51  GLY D C   1 
ATOM   322   O  O   . GLY A 1 104 ? 114.665 115.027 117.620 1.00 31.20  ? 51  GLY D O   1 
ATOM   323   N  N   . PRO A 1 105 ? 116.819 115.545 117.985 1.00 32.54  ? 52  PRO D N   1 
ATOM   324   C  CA  . PRO A 1 105 ? 116.529 116.163 119.281 1.00 33.15  ? 52  PRO D CA  1 
ATOM   325   C  C   . PRO A 1 105 ? 115.616 117.369 119.158 1.00 36.41  ? 52  PRO D C   1 
ATOM   326   O  O   . PRO A 1 105 ? 115.604 118.076 118.149 1.00 38.24  ? 52  PRO D O   1 
ATOM   327   C  CB  . PRO A 1 105 ? 117.912 116.579 119.794 1.00 29.26  ? 52  PRO D CB  1 
ATOM   328   C  CG  . PRO A 1 105 ? 118.883 115.839 118.963 1.00 31.54  ? 52  PRO D CG  1 
ATOM   329   C  CD  . PRO A 1 105 ? 118.241 115.638 117.637 1.00 31.79  ? 52  PRO D CD  1 
ATOM   330   N  N   . VAL A 1 106 ? 114.853 117.602 120.215 1.00 33.50  ? 53  VAL D N   1 
ATOM   331   C  CA  . VAL A 1 106 ? 114.014 118.782 120.354 1.00 30.63  ? 53  VAL D CA  1 
ATOM   332   C  C   . VAL A 1 106 ? 114.709 119.736 121.309 1.00 34.21  ? 53  VAL D C   1 
ATOM   333   O  O   . VAL A 1 106 ? 115.259 119.313 122.330 1.00 42.08  ? 53  VAL D O   1 
ATOM   334   C  CB  . VAL A 1 106 ? 112.609 118.410 120.859 1.00 30.04  ? 53  VAL D CB  1 
ATOM   335   C  CG1 . VAL A 1 106 ? 111.789 119.648 121.102 1.00 33.04  ? 53  VAL D CG1 1 
ATOM   336   C  CG2 . VAL A 1 106 ? 111.923 117.522 119.863 1.00 31.53  ? 53  VAL D CG2 1 
ATOM   337   N  N   . SER A 1 107 ? 114.729 121.014 120.958 1.00 34.93  ? 54  SER D N   1 
ATOM   338   C  CA  . SER A 1 107 ? 115.390 122.040 121.755 1.00 37.08  ? 54  SER D CA  1 
ATOM   339   C  C   . SER A 1 107 ? 114.343 123.013 122.285 1.00 41.99  ? 54  SER D C   1 
ATOM   340   O  O   . SER A 1 107 ? 113.732 123.757 121.513 1.00 42.95  ? 54  SER D O   1 
ATOM   341   C  CB  . SER A 1 107 ? 116.446 122.758 120.924 1.00 37.07  ? 54  SER D CB  1 
ATOM   342   O  OG  . SER A 1 107 ? 117.049 123.794 121.668 1.00 46.82  ? 54  SER D OG  1 
ATOM   343   N  N   . ASP A 1 108 ? 114.147 123.017 123.605 1.00 45.29  ? 55  ASP D N   1 
ATOM   344   C  CA  . ASP A 1 108 ? 113.174 123.925 124.208 1.00 46.44  ? 55  ASP D CA  1 
ATOM   345   C  C   . ASP A 1 108 ? 113.627 125.375 124.114 1.00 48.17  ? 55  ASP D C   1 
ATOM   346   O  O   . ASP A 1 108 ? 112.801 126.275 123.940 1.00 51.31  ? 55  ASP D O   1 
ATOM   347   C  CB  . ASP A 1 108 ? 112.934 123.562 125.672 1.00 47.01  ? 55  ASP D CB  1 
ATOM   348   C  CG  . ASP A 1 108 ? 112.423 122.152 125.855 1.00 55.28  ? 55  ASP D CG  1 
ATOM   349   O  OD1 . ASP A 1 108 ? 111.887 121.580 124.887 1.00 58.01  ? 55  ASP D OD1 1 
ATOM   350   O  OD2 . ASP A 1 108 ? 112.550 121.619 126.978 1.00 55.36  ? 55  ASP D OD2 1 
ATOM   351   N  N   . HIS A 1 109 ? 114.928 125.623 124.266 1.00 45.03  ? 56  HIS D N   1 
ATOM   352   C  CA  . HIS A 1 109 ? 115.417 126.995 124.333 1.00 48.12  ? 56  HIS D CA  1 
ATOM   353   C  C   . HIS A 1 109 ? 115.233 127.713 123.005 1.00 51.68  ? 56  HIS D C   1 
ATOM   354   O  O   . HIS A 1 109 ? 114.716 128.834 122.961 1.00 57.79  ? 56  HIS D O   1 
ATOM   355   C  CB  . HIS A 1 109 ? 116.885 127.007 124.751 1.00 55.58  ? 56  HIS D CB  1 
ATOM   356   C  CG  . HIS A 1 109 ? 117.438 128.381 124.972 1.00 66.66  ? 56  HIS D CG  1 
ATOM   357   N  ND1 . HIS A 1 109 ? 118.790 128.638 125.028 1.00 69.61  ? 56  HIS D ND1 1 
ATOM   358   C  CD2 . HIS A 1 109 ? 116.821 129.572 125.155 1.00 69.01  ? 56  HIS D CD2 1 
ATOM   359   C  CE1 . HIS A 1 109 ? 118.982 129.929 125.232 1.00 72.51  ? 56  HIS D CE1 1 
ATOM   360   N  NE2 . HIS A 1 109 ? 117.803 130.519 125.311 1.00 73.18  ? 56  HIS D NE2 1 
ATOM   361   N  N   . ASP A 1 110 ? 115.644 127.083 121.913 1.00 48.58  ? 57  ASP D N   1 
ATOM   362   C  CA  . ASP A 1 110 ? 115.511 127.673 120.592 1.00 46.54  ? 57  ASP D CA  1 
ATOM   363   C  C   . ASP A 1 110 ? 114.153 127.423 119.963 1.00 44.10  ? 57  ASP D C   1 
ATOM   364   O  O   . ASP A 1 110 ? 113.842 128.043 118.943 1.00 45.26  ? 57  ASP D O   1 
ATOM   365   C  CB  . ASP A 1 110 ? 116.604 127.132 119.674 1.00 47.40  ? 57  ASP D CB  1 
ATOM   366   C  CG  . ASP A 1 110 ? 117.988 127.457 120.175 1.00 56.02  ? 57  ASP D CG  1 
ATOM   367   O  OD1 . ASP A 1 110 ? 118.184 128.578 120.685 1.00 61.99  ? 57  ASP D OD1 1 
ATOM   368   O  OD2 . ASP A 1 110 ? 118.878 126.592 120.063 1.00 58.48  ? 57  ASP D OD2 1 
ATOM   369   N  N   . MET A 1 111 ? 113.344 126.539 120.546 1.00 41.86  ? 58  MET D N   1 
ATOM   370   C  CA  . MET A 1 111 ? 112.026 126.187 120.026 1.00 40.43  ? 58  MET D CA  1 
ATOM   371   C  C   . MET A 1 111 ? 112.129 125.666 118.593 1.00 43.70  ? 58  MET D C   1 
ATOM   372   O  O   . MET A 1 111 ? 111.596 126.244 117.647 1.00 43.94  ? 58  MET D O   1 
ATOM   373   C  CB  . MET A 1 111 ? 111.064 127.371 120.125 1.00 40.72  ? 58  MET D CB  1 
ATOM   374   C  CG  . MET A 1 111 ? 110.711 127.742 121.546 1.00 45.29  ? 58  MET D CG  1 
ATOM   375   S  SD  . MET A 1 111 ? 109.566 129.120 121.652 1.00 63.36  ? 58  MET D SD  1 
ATOM   376   C  CE  . MET A 1 111 ? 109.706 129.496 123.392 1.00 52.49  ? 58  MET D CE  1 
ATOM   377   N  N   . GLU A 1 112 ? 112.833 124.549 118.457 1.00 42.34  ? 59  GLU D N   1 
ATOM   378   C  CA  . GLU A 1 112 ? 113.081 123.948 117.157 1.00 34.56  ? 59  GLU D CA  1 
ATOM   379   C  C   . GLU A 1 112 ? 113.383 122.474 117.354 1.00 34.70  ? 59  GLU D C   1 
ATOM   380   O  O   . GLU A 1 112 ? 113.651 122.018 118.465 1.00 39.79  ? 59  GLU D O   1 
ATOM   381   C  CB  . GLU A 1 112 ? 114.240 124.631 116.439 1.00 33.02  ? 59  GLU D CB  1 
ATOM   382   C  CG  . GLU A 1 112 ? 115.555 124.402 117.127 1.00 38.85  ? 59  GLU D CG  1 
ATOM   383   C  CD  . GLU A 1 112 ? 116.704 125.066 116.420 1.00 49.14  ? 59  GLU D CD  1 
ATOM   384   O  OE1 . GLU A 1 112 ? 116.550 125.419 115.236 1.00 52.77  ? 59  GLU D OE1 1 
ATOM   385   O  OE2 . GLU A 1 112 ? 117.769 125.231 117.045 1.00 48.94  ? 59  GLU D OE2 1 
ATOM   386   N  N   . TYR A 1 113 ? 113.338 121.733 116.253 1.00 32.63  ? 60  TYR D N   1 
ATOM   387   C  CA  . TYR A 1 113 ? 113.728 120.332 116.279 1.00 29.89  ? 60  TYR D CA  1 
ATOM   388   C  C   . TYR A 1 113 ? 114.356 119.960 114.948 1.00 30.77  ? 60  TYR D C   1 
ATOM   389   O  O   . TYR A 1 113 ? 114.073 120.572 113.918 1.00 32.50  ? 60  TYR D O   1 
ATOM   390   C  CB  . TYR A 1 113 ? 112.541 119.417 116.581 1.00 30.09  ? 60  TYR D CB  1 
ATOM   391   C  CG  . TYR A 1 113 ? 111.535 119.338 115.472 1.00 32.88  ? 60  TYR D CG  1 
ATOM   392   C  CD1 . TYR A 1 113 ? 110.586 120.330 115.304 1.00 32.97  ? 60  TYR D CD1 1 
ATOM   393   C  CD2 . TYR A 1 113 ? 111.529 118.272 114.595 1.00 33.93  ? 60  TYR D CD2 1 
ATOM   394   C  CE1 . TYR A 1 113 ? 109.670 120.264 114.292 1.00 32.04  ? 60  TYR D CE1 1 
ATOM   395   C  CE2 . TYR A 1 113 ? 110.616 118.200 113.584 1.00 33.99  ? 60  TYR D CE2 1 
ATOM   396   C  CZ  . TYR A 1 113 ? 109.691 119.196 113.438 1.00 34.65  ? 60  TYR D CZ  1 
ATOM   397   O  OH  . TYR A 1 113 ? 108.777 119.123 112.426 1.00 37.83  ? 60  TYR D OH  1 
ATOM   398   N  N   . THR A 1 114 ? 115.208 118.943 114.983 1.00 30.20  ? 61  THR D N   1 
ATOM   399   C  CA  . THR A 1 114 ? 115.864 118.414 113.799 1.00 29.43  ? 61  THR D CA  1 
ATOM   400   C  C   . THR A 1 114 ? 115.186 117.124 113.359 1.00 31.41  ? 61  THR D C   1 
ATOM   401   O  O   . THR A 1 114 ? 114.654 116.377 114.180 1.00 35.06  ? 61  THR D O   1 
ATOM   402   C  CB  . THR A 1 114 ? 117.344 118.153 114.073 1.00 32.10  ? 61  THR D CB  1 
ATOM   403   O  OG1 . THR A 1 114 ? 117.938 119.323 114.636 1.00 41.11  ? 61  THR D OG1 1 
ATOM   404   C  CG2 . THR A 1 114 ? 118.071 117.817 112.797 1.00 33.45  ? 61  THR D CG2 1 
ATOM   405   N  N   . ILE A 1 115 ? 115.189 116.875 112.054 1.00 31.44  ? 62  ILE D N   1 
ATOM   406   C  CA  . ILE A 1 115 ? 114.608 115.650 111.513 1.00 30.89  ? 62  ILE D CA  1 
ATOM   407   C  C   . ILE A 1 115 ? 115.309 115.308 110.204 1.00 31.60  ? 62  ILE D C   1 
ATOM   408   O  O   . ILE A 1 115 ? 115.510 116.177 109.354 1.00 32.48  ? 62  ILE D O   1 
ATOM   409   C  CB  . ILE A 1 115 ? 113.086 115.796 111.323 1.00 29.71  ? 62  ILE D CB  1 
ATOM   410   C  CG1 . ILE A 1 115 ? 112.484 114.521 110.757 1.00 31.86  ? 62  ILE D CG1 1 
ATOM   411   C  CG2 . ILE A 1 115 ? 112.757 116.968 110.426 1.00 25.31  ? 62  ILE D CG2 1 
ATOM   412   C  CD1 . ILE A 1 115 ? 111.009 114.621 110.539 1.00 31.32  ? 62  ILE D CD1 1 
ATOM   413   N  N   . ASP A 1 116 ? 115.685 114.044 110.038 1.00 31.38  ? 63  ASP D N   1 
ATOM   414   C  CA  . ASP A 1 116 ? 116.325 113.562 108.820 1.00 26.88  ? 63  ASP D CA  1 
ATOM   415   C  C   . ASP A 1 116 ? 115.348 112.698 108.038 1.00 27.47  ? 63  ASP D C   1 
ATOM   416   O  O   . ASP A 1 116 ? 114.811 111.724 108.573 1.00 31.36  ? 63  ASP D O   1 
ATOM   417   C  CB  . ASP A 1 116 ? 117.589 112.767 109.135 1.00 30.15  ? 63  ASP D CB  1 
ATOM   418   C  CG  . ASP A 1 116 ? 118.706 113.633 109.680 1.00 44.72  ? 63  ASP D CG  1 
ATOM   419   O  OD1 . ASP A 1 116 ? 118.616 114.072 110.844 1.00 48.72  ? 63  ASP D OD1 1 
ATOM   420   O  OD2 . ASP A 1 116 ? 119.682 113.876 108.945 1.00 49.55  ? 63  ASP D OD2 1 
ATOM   421   N  N   . VAL A 1 117 ? 115.135 113.037 106.769 1.00 24.53  ? 64  VAL D N   1 
ATOM   422   C  CA  . VAL A 1 117 ? 114.076 112.422 105.982 1.00 23.77  ? 64  VAL D CA  1 
ATOM   423   C  C   . VAL A 1 117 ? 114.598 111.979 104.625 1.00 24.73  ? 64  VAL D C   1 
ATOM   424   O  O   . VAL A 1 117 ? 115.560 112.535 104.088 1.00 26.25  ? 64  VAL D O   1 
ATOM   425   C  CB  . VAL A 1 117 ? 112.874 113.378 105.788 1.00 25.66  ? 64  VAL D CB  1 
ATOM   426   C  CG1 . VAL A 1 117 ? 112.330 113.850 107.117 1.00 27.50  ? 64  VAL D CG1 1 
ATOM   427   C  CG2 . VAL A 1 117 ? 113.267 114.563 104.947 1.00 22.62  ? 64  VAL D CG2 1 
ATOM   428   N  N   . PHE A 1 118 ? 113.960 110.944 104.087 1.00 23.49  ? 65  PHE D N   1 
ATOM   429   C  CA  . PHE A 1 118 ? 113.886 110.706 102.652 1.00 21.32  ? 65  PHE D CA  1 
ATOM   430   C  C   . PHE A 1 118 ? 112.607 111.376 102.168 1.00 25.10  ? 65  PHE D C   1 
ATOM   431   O  O   . PHE A 1 118 ? 111.508 110.980 102.565 1.00 31.00  ? 65  PHE D O   1 
ATOM   432   C  CB  . PHE A 1 118 ? 113.857 109.217 102.327 1.00 20.51  ? 65  PHE D CB  1 
ATOM   433   C  CG  . PHE A 1 118 ? 115.132 108.493 102.621 1.00 23.02  ? 65  PHE D CG  1 
ATOM   434   C  CD1 . PHE A 1 118 ? 116.334 109.160 102.661 1.00 24.47  ? 65  PHE D CD1 1 
ATOM   435   C  CD2 . PHE A 1 118 ? 115.124 107.132 102.844 1.00 22.79  ? 65  PHE D CD2 1 
ATOM   436   C  CE1 . PHE A 1 118 ? 117.498 108.487 102.918 1.00 23.24  ? 65  PHE D CE1 1 
ATOM   437   C  CE2 . PHE A 1 118 ? 116.286 106.459 103.099 1.00 20.00  ? 65  PHE D CE2 1 
ATOM   438   C  CZ  . PHE A 1 118 ? 117.474 107.136 103.139 1.00 21.57  ? 65  PHE D CZ  1 
ATOM   439   N  N   . PHE A 1 119 ? 112.750 112.398 101.336 1.00 24.48  ? 66  PHE D N   1 
ATOM   440   C  CA  . PHE A 1 119 ? 111.634 113.154 100.786 1.00 22.41  ? 66  PHE D CA  1 
ATOM   441   C  C   . PHE A 1 119 ? 111.407 112.688 99.356  1.00 26.65  ? 66  PHE D C   1 
ATOM   442   O  O   . PHE A 1 119 ? 112.298 112.832 98.511  1.00 29.83  ? 66  PHE D O   1 
ATOM   443   C  CB  . PHE A 1 119 ? 111.955 114.647 100.836 1.00 22.93  ? 66  PHE D CB  1 
ATOM   444   C  CG  . PHE A 1 119 ? 110.801 115.538 100.513 1.00 25.49  ? 66  PHE D CG  1 
ATOM   445   C  CD1 . PHE A 1 119 ? 109.749 115.670 101.391 1.00 27.25  ? 66  PHE D CD1 1 
ATOM   446   C  CD2 . PHE A 1 119 ? 110.788 116.282 99.353  1.00 25.74  ? 66  PHE D CD2 1 
ATOM   447   C  CE1 . PHE A 1 119 ? 108.701 116.498 101.102 1.00 27.78  ? 66  PHE D CE1 1 
ATOM   448   C  CE2 . PHE A 1 119 ? 109.737 117.110 99.066  1.00 24.63  ? 66  PHE D CE2 1 
ATOM   449   C  CZ  . PHE A 1 119 ? 108.695 117.216 99.940  1.00 28.71  ? 66  PHE D CZ  1 
ATOM   450   N  N   . ARG A 1 120 ? 110.233 112.116 99.086  1.00 28.44  ? 67  ARG D N   1 
ATOM   451   C  CA  . ARG A 1 120 ? 109.935 111.507 97.796  1.00 26.56  ? 67  ARG D CA  1 
ATOM   452   C  C   . ARG A 1 120 ? 108.828 112.276 97.094  1.00 27.81  ? 67  ARG D C   1 
ATOM   453   O  O   . ARG A 1 120 ? 107.798 112.574 97.707  1.00 33.31  ? 67  ARG D O   1 
ATOM   454   C  CB  . ARG A 1 120 ? 109.512 110.048 97.967  1.00 26.74  ? 67  ARG D CB  1 
ATOM   455   C  CG  . ARG A 1 120 ? 110.350 109.261 98.954  1.00 29.71  ? 67  ARG D CG  1 
ATOM   456   C  CD  . ARG A 1 120 ? 110.125 107.775 98.777  1.00 30.16  ? 67  ARG D CD  1 
ATOM   457   N  NE  . ARG A 1 120 ? 110.999 106.976 99.624  1.00 33.25  ? 67  ARG D NE  1 
ATOM   458   C  CZ  . ARG A 1 120 ? 110.580 106.201 100.612 1.00 33.61  ? 67  ARG D CZ  1 
ATOM   459   N  NH1 . ARG A 1 120 ? 109.298 106.095 100.910 1.00 35.73  ? 67  ARG D NH1 1 
ATOM   460   N  NH2 . ARG A 1 120 ? 111.470 105.506 101.312 1.00 31.54  ? 67  ARG D NH2 1 
ATOM   461   N  N   . GLN A 1 121 ? 109.033 112.572 95.807  1.00 27.20  ? 68  GLN D N   1 
ATOM   462   C  CA  . GLN A 1 121 ? 108.040 113.230 94.971  1.00 26.62  ? 68  GLN D CA  1 
ATOM   463   C  C   . GLN A 1 121 ? 107.873 112.463 93.668  1.00 27.71  ? 68  GLN D C   1 
ATOM   464   O  O   . GLN A 1 121 ? 108.787 111.774 93.212  1.00 30.77  ? 68  GLN D O   1 
ATOM   465   C  CB  . GLN A 1 121 ? 108.435 114.671 94.663  1.00 26.73  ? 68  GLN D CB  1 
ATOM   466   C  CG  . GLN A 1 121 ? 108.460 115.576 95.864  1.00 28.02  ? 68  GLN D CG  1 
ATOM   467   C  CD  . GLN A 1 121 ? 109.160 116.876 95.581  1.00 31.79  ? 68  GLN D CD  1 
ATOM   468   O  OE1 . GLN A 1 121 ? 108.530 117.921 95.472  1.00 37.72  ? 68  GLN D OE1 1 
ATOM   469   N  NE2 . GLN A 1 121 ? 110.475 116.823 95.471  1.00 30.68  ? 68  GLN D NE2 1 
ATOM   470   N  N   . SER A 1 122 ? 106.690 112.581 93.077  1.00 26.62  ? 69  SER D N   1 
ATOM   471   C  CA  . SER A 1 122 ? 106.396 111.880 91.837  1.00 27.68  ? 69  SER D CA  1 
ATOM   472   C  C   . SER A 1 122 ? 105.412 112.701 91.024  1.00 29.54  ? 69  SER D C   1 
ATOM   473   O  O   . SER A 1 122 ? 104.457 113.250 91.572  1.00 35.07  ? 69  SER D O   1 
ATOM   474   C  CB  . SER A 1 122 ? 105.822 110.489 92.114  1.00 30.36  ? 69  SER D CB  1 
ATOM   475   O  OG  . SER A 1 122 ? 105.486 109.823 90.916  1.00 36.69  ? 69  SER D OG  1 
ATOM   476   N  N   . TRP A 1 123 ? 105.646 112.775 89.718  1.00 31.88  ? 70  TRP D N   1 
ATOM   477   C  CA  . TRP A 1 123 ? 104.732 113.535 88.873  1.00 31.52  ? 70  TRP D CA  1 
ATOM   478   C  C   . TRP A 1 123 ? 104.816 113.049 87.436  1.00 37.05  ? 70  TRP D C   1 
ATOM   479   O  O   . TRP A 1 123 ? 105.806 112.456 87.017  1.00 41.31  ? 70  TRP D O   1 
ATOM   480   C  CB  . TRP A 1 123 ? 105.015 115.039 88.944  1.00 30.56  ? 70  TRP D CB  1 
ATOM   481   C  CG  . TRP A 1 123 ? 106.313 115.438 88.342  1.00 32.43  ? 70  TRP D CG  1 
ATOM   482   C  CD1 . TRP A 1 123 ? 106.526 115.889 87.076  1.00 33.64  ? 70  TRP D CD1 1 
ATOM   483   C  CD2 . TRP A 1 123 ? 107.587 115.428 88.982  1.00 30.77  ? 70  TRP D CD2 1 
ATOM   484   N  NE1 . TRP A 1 123 ? 107.854 116.158 86.886  1.00 33.18  ? 70  TRP D NE1 1 
ATOM   485   C  CE2 . TRP A 1 123 ? 108.528 115.882 88.045  1.00 31.86  ? 70  TRP D CE2 1 
ATOM   486   C  CE3 . TRP A 1 123 ? 108.025 115.079 90.259  1.00 30.98  ? 70  TRP D CE3 1 
ATOM   487   C  CZ2 . TRP A 1 123 ? 109.876 115.990 88.343  1.00 32.25  ? 70  TRP D CZ2 1 
ATOM   488   C  CZ3 . TRP A 1 123 ? 109.359 115.187 90.549  1.00 32.39  ? 70  TRP D CZ3 1 
ATOM   489   C  CH2 . TRP A 1 123 ? 110.271 115.636 89.598  1.00 32.28  ? 70  TRP D CH2 1 
ATOM   490   N  N   . LYS A 1 124 ? 103.760 113.327 86.681  1.00 40.14  ? 71  LYS D N   1 
ATOM   491   C  CA  . LYS A 1 124 ? 103.674 112.933 85.284  1.00 44.92  ? 71  LYS D CA  1 
ATOM   492   C  C   . LYS A 1 124 ? 104.230 114.033 84.391  1.00 47.35  ? 71  LYS D C   1 
ATOM   493   O  O   . LYS A 1 124 ? 103.970 115.217 84.610  1.00 52.03  ? 71  LYS D O   1 
ATOM   494   C  CB  . LYS A 1 124 ? 102.223 112.634 84.911  1.00 48.30  ? 71  LYS D CB  1 
ATOM   495   C  CG  . LYS A 1 124 ? 101.958 112.490 83.427  1.00 53.67  ? 71  LYS D CG  1 
ATOM   496   C  CD  . LYS A 1 124 ? 102.526 111.199 82.889  1.00 57.14  ? 71  LYS D CD  1 
ATOM   497   C  CE  . LYS A 1 124 ? 101.809 109.999 83.478  1.00 59.46  ? 71  LYS D CE  1 
ATOM   498   N  NZ  . LYS A 1 124 ? 100.390 109.918 83.049  1.00 58.60  ? 71  LYS D NZ  1 
ATOM   499   N  N   . ASP A 1 125 ? 105.009 113.634 83.388  1.00 45.32  ? 72  ASP D N   1 
ATOM   500   C  CA  . ASP A 1 125 ? 105.563 114.565 82.406  1.00 47.27  ? 72  ASP D CA  1 
ATOM   501   C  C   . ASP A 1 125 ? 105.457 113.901 81.037  1.00 52.76  ? 72  ASP D C   1 
ATOM   502   O  O   . ASP A 1 125 ? 106.253 113.019 80.709  1.00 55.67  ? 72  ASP D O   1 
ATOM   503   C  CB  . ASP A 1 125 ? 107.002 114.927 82.739  1.00 46.21  ? 72  ASP D CB  1 
ATOM   504   C  CG  . ASP A 1 125 ? 107.478 116.164 82.010  1.00 48.97  ? 72  ASP D CG  1 
ATOM   505   O  OD1 . ASP A 1 125 ? 106.868 116.532 80.988  1.00 48.20  ? 72  ASP D OD1 1 
ATOM   506   O  OD2 . ASP A 1 125 ? 108.463 116.775 82.466  1.00 49.73  ? 72  ASP D OD2 1 
ATOM   507   N  N   . GLU A 1 126 ? 104.478 114.328 80.240  1.00 55.60  ? 73  GLU D N   1 
ATOM   508   C  CA  . GLU A 1 126 ? 104.256 113.709 78.940  1.00 58.39  ? 73  GLU D CA  1 
ATOM   509   C  C   . GLU A 1 126 ? 105.394 113.967 77.965  1.00 55.32  ? 73  GLU D C   1 
ATOM   510   O  O   . GLU A 1 126 ? 105.489 113.269 76.952  1.00 56.84  ? 73  GLU D O   1 
ATOM   511   C  CB  . GLU A 1 126 ? 102.941 114.199 78.335  1.00 70.32  ? 73  GLU D CB  1 
ATOM   512   C  CG  . GLU A 1 126 ? 101.701 113.656 79.026  1.00 80.01  ? 73  GLU D CG  1 
ATOM   513   C  CD  . GLU A 1 126 ? 100.419 114.133 78.376  1.00 96.31  ? 73  GLU D CD  1 
ATOM   514   O  OE1 . GLU A 1 126 ? 100.493 115.022 77.502  1.00 100.00 ? 73  GLU D OE1 1 
ATOM   515   O  OE2 . GLU A 1 126 ? 99.338  113.618 78.736  1.00 99.15  ? 73  GLU D OE2 1 
ATOM   516   N  N   . ARG A 1 127 ? 106.251 114.949 78.236  1.00 51.69  ? 74  ARG D N   1 
ATOM   517   C  CA  . ARG A 1 127 ? 107.408 115.186 77.384  1.00 48.81  ? 74  ARG D CA  1 
ATOM   518   C  C   . ARG A 1 127 ? 108.469 114.105 77.515  1.00 49.68  ? 74  ARG D C   1 
ATOM   519   O  O   . ARG A 1 127 ? 109.398 114.073 76.704  1.00 49.59  ? 74  ARG D O   1 
ATOM   520   C  CB  . ARG A 1 127 ? 108.025 116.545 77.703  1.00 45.64  ? 74  ARG D CB  1 
ATOM   521   C  CG  . ARG A 1 127 ? 107.240 117.726 77.184  1.00 42.10  ? 74  ARG D CG  1 
ATOM   522   C  CD  . ARG A 1 127 ? 107.881 119.032 77.608  1.00 41.96  ? 74  ARG D CD  1 
ATOM   523   N  NE  . ARG A 1 127 ? 107.887 119.200 79.055  1.00 43.26  ? 74  ARG D NE  1 
ATOM   524   C  CZ  . ARG A 1 127 ? 108.448 120.222 79.685  1.00 44.99  ? 74  ARG D CZ  1 
ATOM   525   N  NH1 . ARG A 1 127 ? 109.057 121.191 79.023  1.00 48.28  ? 74  ARG D NH1 1 
ATOM   526   N  NH2 . ARG A 1 127 ? 108.401 120.271 81.010  1.00 42.35  ? 74  ARG D NH2 1 
ATOM   527   N  N   . LEU A 1 128 ? 108.357 113.223 78.506  1.00 50.56  ? 75  LEU D N   1 
ATOM   528   C  CA  . LEU A 1 128 ? 109.376 112.219 78.775  1.00 50.36  ? 75  LEU D CA  1 
ATOM   529   C  C   . LEU A 1 128 ? 108.880 110.798 78.531  1.00 52.89  ? 75  LEU D C   1 
ATOM   530   O  O   . LEU A 1 128 ? 109.418 109.853 79.111  1.00 56.64  ? 75  LEU D O   1 
ATOM   531   C  CB  . LEU A 1 128 ? 109.893 112.365 80.206  1.00 46.08  ? 75  LEU D CB  1 
ATOM   532   C  CG  . LEU A 1 128 ? 110.527 113.714 80.551  1.00 44.45  ? 75  LEU D CG  1 
ATOM   533   C  CD1 . LEU A 1 128 ? 111.080 113.698 81.950  1.00 38.14  ? 75  LEU D CD1 1 
ATOM   534   C  CD2 . LEU A 1 128 ? 111.616 114.063 79.561  1.00 46.20  ? 75  LEU D CD2 1 
ATOM   535   N  N   . LYS A 1 129 ? 107.856 110.626 77.701  1.00 53.32  ? 76  LYS D N   1 
ATOM   536   C  CA  . LYS A 1 129 ? 107.480 109.289 77.266  1.00 51.19  ? 76  LYS D CA  1 
ATOM   537   C  C   . LYS A 1 129 ? 108.558 108.720 76.358  1.00 56.67  ? 76  LYS D C   1 
ATOM   538   O  O   . LYS A 1 129 ? 109.142 109.434 75.540  1.00 59.35  ? 76  LYS D O   1 
ATOM   539   C  CB  . LYS A 1 129 ? 106.146 109.309 76.526  1.00 54.63  ? 76  LYS D CB  1 
ATOM   540   C  CG  . LYS A 1 129 ? 104.923 109.332 77.413  1.00 62.48  ? 76  LYS D CG  1 
ATOM   541   C  CD  . LYS A 1 129 ? 103.660 109.103 76.599  1.00 69.48  ? 76  LYS D CD  1 
ATOM   542   C  CE  . LYS A 1 129 ? 102.418 109.191 77.467  1.00 76.97  ? 76  LYS D CE  1 
ATOM   543   N  NZ  . LYS A 1 129 ? 102.307 110.527 78.109  1.00 76.99  ? 76  LYS D NZ  1 
ATOM   544   N  N   . PHE A 1 130 ? 108.824 107.427 76.502  1.00 56.99  ? 77  PHE D N   1 
ATOM   545   C  CA  . PHE A 1 130 ? 109.767 106.740 75.637  1.00 57.27  ? 77  PHE D CA  1 
ATOM   546   C  C   . PHE A 1 130 ? 109.277 105.320 75.410  1.00 58.45  ? 77  PHE D C   1 
ATOM   547   O  O   . PHE A 1 130 ? 108.261 104.892 75.962  1.00 58.65  ? 77  PHE D O   1 
ATOM   548   C  CB  . PHE A 1 130 ? 111.183 106.751 76.223  1.00 55.21  ? 77  PHE D CB  1 
ATOM   549   C  CG  . PHE A 1 130 ? 111.314 106.004 77.517  1.00 57.46  ? 77  PHE D CG  1 
ATOM   550   C  CD1 . PHE A 1 130 ? 111.595 104.652 77.525  1.00 57.14  ? 77  PHE D CD1 1 
ATOM   551   C  CD2 . PHE A 1 130 ? 111.165 106.654 78.722  1.00 54.95  ? 77  PHE D CD2 1 
ATOM   552   C  CE1 . PHE A 1 130 ? 111.710 103.968 78.703  1.00 57.60  ? 77  PHE D CE1 1 
ATOM   553   C  CE2 . PHE A 1 130 ? 111.285 105.970 79.904  1.00 52.37  ? 77  PHE D CE2 1 
ATOM   554   C  CZ  . PHE A 1 130 ? 111.559 104.627 79.894  1.00 54.97  ? 77  PHE D CZ  1 
ATOM   555   N  N   . LYS A 1 131 ? 110.009 104.590 74.577  1.00 62.40  ? 78  LYS D N   1 
ATOM   556   C  CA  . LYS A 1 131 ? 109.722 103.186 74.328  1.00 67.57  ? 78  LYS D CA  1 
ATOM   557   C  C   . LYS A 1 131 ? 111.039 102.486 74.041  1.00 70.64  ? 78  LYS D C   1 
ATOM   558   O  O   . LYS A 1 131 ? 111.784 102.909 73.154  1.00 66.29  ? 78  LYS D O   1 
ATOM   559   C  CB  . LYS A 1 131 ? 108.749 103.011 73.158  1.00 67.40  ? 78  LYS D CB  1 
ATOM   560   C  CG  . LYS A 1 131 ? 108.187 101.608 73.039  1.00 71.39  ? 78  LYS D CG  1 
ATOM   561   C  CD  . LYS A 1 131 ? 107.297 101.459 71.816  1.00 78.94  ? 78  LYS D CD  1 
ATOM   562   C  CE  . LYS A 1 131 ? 106.803 100.029 71.673  1.00 86.16  ? 78  LYS D CE  1 
ATOM   563   N  NZ  . LYS A 1 131 ? 106.040 99.831  70.411  1.00 91.30  ? 78  LYS D NZ  1 
ATOM   564   N  N   . GLY A 1 132 ? 111.324 101.430 74.796  1.00 72.16  ? 79  GLY D N   1 
ATOM   565   C  CA  . GLY A 1 132 ? 112.575 100.728 74.662  1.00 71.95  ? 79  GLY D CA  1 
ATOM   566   C  C   . GLY A 1 132 ? 112.599 99.411  75.407  1.00 76.66  ? 79  GLY D C   1 
ATOM   567   O  O   . GLY A 1 132 ? 111.584 98.946  75.933  1.00 77.58  ? 79  GLY D O   1 
ATOM   568   N  N   . PRO A 1 133 ? 113.773 98.777  75.454  1.00 76.46  ? 80  PRO D N   1 
ATOM   569   C  CA  . PRO A 1 133 ? 113.875 97.463  76.109  1.00 77.12  ? 80  PRO D CA  1 
ATOM   570   C  C   . PRO A 1 133 ? 113.531 97.475  77.587  1.00 75.77  ? 80  PRO D C   1 
ATOM   571   O  O   . PRO A 1 133 ? 113.057 96.456  78.104  1.00 74.38  ? 80  PRO D O   1 
ATOM   572   C  CB  . PRO A 1 133 ? 115.339 97.068  75.870  1.00 72.23  ? 80  PRO D CB  1 
ATOM   573   C  CG  . PRO A 1 133 ? 116.039 98.336  75.550  1.00 71.14  ? 80  PRO D CG  1 
ATOM   574   C  CD  . PRO A 1 133 ? 115.046 99.194  74.847  1.00 70.74  ? 80  PRO D CD  1 
ATOM   575   N  N   . MET A 1 134 ? 113.760 98.579  78.290  1.00 73.15  ? 81  MET D N   1 
ATOM   576   C  CA  . MET A 1 134 ? 113.450 98.678  79.708  1.00 70.19  ? 81  MET D CA  1 
ATOM   577   C  C   . MET A 1 134 ? 112.258 99.596  79.926  1.00 69.22  ? 81  MET D C   1 
ATOM   578   O  O   . MET A 1 134 ? 112.139 100.639 79.278  1.00 69.76  ? 81  MET D O   1 
ATOM   579   C  CB  . MET A 1 134 ? 114.645 99.194  80.506  1.00 71.25  ? 81  MET D CB  1 
ATOM   580   C  CG  . MET A 1 134 ? 115.761 98.188  80.649  1.00 76.79  ? 81  MET D CG  1 
ATOM   581   S  SD  . MET A 1 134 ? 116.734 98.493  82.126  1.00 95.56  ? 81  MET D SD  1 
ATOM   582   C  CE  . MET A 1 134 ? 117.201 100.190 81.844  1.00 71.23  ? 81  MET D CE  1 
ATOM   583   N  N   . THR A 1 135 ? 111.371 99.196  80.838  1.00 69.66  ? 82  THR D N   1 
ATOM   584   C  CA  . THR A 1 135 ? 110.221 100.027 81.172  1.00 67.03  ? 82  THR D CA  1 
ATOM   585   C  C   . THR A 1 135 ? 110.585 101.188 82.086  1.00 62.28  ? 82  THR D C   1 
ATOM   586   O  O   . THR A 1 135 ? 109.966 102.252 81.994  1.00 62.03  ? 82  THR D O   1 
ATOM   587   C  CB  . THR A 1 135 ? 109.125 99.185  81.823  1.00 62.91  ? 82  THR D CB  1 
ATOM   588   O  OG1 . THR A 1 135 ? 109.683 98.410  82.889  1.00 64.69  ? 82  THR D OG1 1 
ATOM   589   C  CG2 . THR A 1 135 ? 108.505 98.257  80.805  1.00 61.94  ? 82  THR D CG2 1 
ATOM   590   N  N   . VAL A 1 136 ? 111.561 101.012 82.972  1.00 59.23  ? 83  VAL D N   1 
ATOM   591   C  CA  . VAL A 1 136 ? 111.954 102.040 83.928  1.00 54.64  ? 83  VAL D CA  1 
ATOM   592   C  C   . VAL A 1 136 ? 113.443 102.304 83.774  1.00 56.78  ? 83  VAL D C   1 
ATOM   593   O  O   . VAL A 1 136 ? 114.245 101.365 83.753  1.00 62.60  ? 83  VAL D O   1 
ATOM   594   C  CB  . VAL A 1 136 ? 111.624 101.633 85.375  1.00 51.37  ? 83  VAL D CB  1 
ATOM   595   C  CG1 . VAL A 1 136 ? 111.957 102.760 86.333  1.00 43.57  ? 83  VAL D CG1 1 
ATOM   596   C  CG2 . VAL A 1 136 ? 110.168 101.248 85.498  1.00 52.04  ? 83  VAL D CG2 1 
ATOM   597   N  N   . LEU A 1 137 ? 113.809 103.577 83.672  1.00 51.83  ? 84  LEU D N   1 
ATOM   598   C  CA  . LEU A 1 137 ? 115.200 104.003 83.647  1.00 46.86  ? 84  LEU D CA  1 
ATOM   599   C  C   . LEU A 1 137 ? 115.555 104.568 85.015  1.00 45.08  ? 84  LEU D C   1 
ATOM   600   O  O   . LEU A 1 137 ? 114.950 105.549 85.458  1.00 43.81  ? 84  LEU D O   1 
ATOM   601   C  CB  . LEU A 1 137 ? 115.435 105.055 82.566  1.00 44.97  ? 84  LEU D CB  1 
ATOM   602   C  CG  . LEU A 1 137 ? 114.884 104.811 81.163  1.00 50.71  ? 84  LEU D CG  1 
ATOM   603   C  CD1 . LEU A 1 137 ? 115.346 105.915 80.239  1.00 49.59  ? 84  LEU D CD1 1 
ATOM   604   C  CD2 . LEU A 1 137 ? 115.298 103.450 80.627  1.00 55.19  ? 84  LEU D CD2 1 
ATOM   605   N  N   . ARG A 1 138 ? 116.526 103.948 85.678  1.00 45.51  ? 85  ARG D N   1 
ATOM   606   C  CA  . ARG A 1 138 ? 117.031 104.407 86.969  1.00 41.72  ? 85  ARG D CA  1 
ATOM   607   C  C   . ARG A 1 138 ? 118.317 105.175 86.698  1.00 42.31  ? 85  ARG D C   1 
ATOM   608   O  O   . ARG A 1 138 ? 119.389 104.580 86.583  1.00 44.33  ? 85  ARG D O   1 
ATOM   609   C  CB  . ARG A 1 138 ? 117.260 103.227 87.907  1.00 41.16  ? 85  ARG D CB  1 
ATOM   610   C  CG  . ARG A 1 138 ? 116.015 102.401 88.167  1.00 42.80  ? 85  ARG D CG  1 
ATOM   611   C  CD  . ARG A 1 138 ? 116.323 101.157 88.977  1.00 44.72  ? 85  ARG D CD  1 
ATOM   612   N  NE  . ARG A 1 138 ? 117.088 100.185 88.207  1.00 59.76  ? 85  ARG D NE  1 
ATOM   613   C  CZ  . ARG A 1 138 ? 116.554 99.206  87.490  1.00 64.01  ? 85  ARG D CZ  1 
ATOM   614   N  NH1 . ARG A 1 138 ? 115.246 99.025  87.434  1.00 60.03  ? 85  ARG D NH1 1 
ATOM   615   N  NH2 . ARG A 1 138 ? 117.353 98.388  86.812  1.00 64.24  ? 85  ARG D NH2 1 
ATOM   616   N  N   . LEU A 1 139 ? 118.213 106.495 86.586  1.00 42.78  ? 86  LEU D N   1 
ATOM   617   C  CA  . LEU A 1 139 ? 119.273 107.285 85.979  1.00 37.93  ? 86  LEU D CA  1 
ATOM   618   C  C   . LEU A 1 139 ? 120.198 107.899 87.021  1.00 40.27  ? 86  LEU D C   1 
ATOM   619   O  O   . LEU A 1 139 ? 119.919 107.916 88.220  1.00 44.33  ? 86  LEU D O   1 
ATOM   620   C  CB  . LEU A 1 139 ? 118.679 108.387 85.101  1.00 37.56  ? 86  LEU D CB  1 
ATOM   621   C  CG  . LEU A 1 139 ? 118.037 107.925 83.798  1.00 40.34  ? 86  LEU D CG  1 
ATOM   622   C  CD1 . LEU A 1 139 ? 117.517 109.113 83.045  1.00 43.70  ? 86  LEU D CD1 1 
ATOM   623   C  CD2 . LEU A 1 139 ? 119.043 107.172 82.968  1.00 38.71  ? 86  LEU D CD2 1 
ATOM   624   N  N   . ASN A 1 140 ? 121.324 108.405 86.530  1.00 40.69  ? 87  ASN D N   1 
ATOM   625   C  CA  . ASN A 1 140 ? 122.220 109.199 87.356  1.00 42.85  ? 87  ASN D CA  1 
ATOM   626   C  C   . ASN A 1 140 ? 121.525 110.490 87.768  1.00 47.24  ? 87  ASN D C   1 
ATOM   627   O  O   . ASN A 1 140 ? 120.831 111.121 86.968  1.00 51.42  ? 87  ASN D O   1 
ATOM   628   C  CB  . ASN A 1 140 ? 123.501 109.494 86.579  1.00 42.61  ? 87  ASN D CB  1 
ATOM   629   C  CG  . ASN A 1 140 ? 124.584 110.089 87.438  1.00 46.15  ? 87  ASN D CG  1 
ATOM   630   O  OD1 . ASN A 1 140 ? 124.395 110.309 88.628  1.00 51.77  ? 87  ASN D OD1 1 
ATOM   631   N  ND2 . ASN A 1 140 ? 125.739 110.341 86.840  1.00 44.36  ? 87  ASN D ND2 1 
ATOM   632   N  N   . ASN A 1 141 ? 121.723 110.893 89.025  1.00 44.89  ? 88  ASN D N   1 
ATOM   633   C  CA  . ASN A 1 141 ? 120.909 111.967 89.583  1.00 43.06  ? 88  ASN D CA  1 
ATOM   634   C  C   . ASN A 1 141 ? 121.166 113.315 88.924  1.00 47.30  ? 88  ASN D C   1 
ATOM   635   O  O   . ASN A 1 141 ? 120.344 114.223 89.080  1.00 50.93  ? 88  ASN D O   1 
ATOM   636   C  CB  . ASN A 1 141 ? 121.122 112.071 91.095  1.00 41.17  ? 88  ASN D CB  1 
ATOM   637   C  CG  . ASN A 1 141 ? 122.508 112.553 91.467  1.00 43.26  ? 88  ASN D CG  1 
ATOM   638   O  OD1 . ASN A 1 141 ? 122.786 113.747 91.449  1.00 43.51  ? 88  ASN D OD1 1 
ATOM   639   N  ND2 . ASN A 1 141 ? 123.376 111.624 91.832  1.00 40.71  ? 88  ASN D ND2 1 
ATOM   640   N  N   . LEU A 1 142 ? 122.270 113.476 88.190  1.00 47.25  ? 89  LEU D N   1 
ATOM   641   C  CA  . LEU A 1 142 ? 122.514 114.748 87.517  1.00 47.27  ? 89  LEU D CA  1 
ATOM   642   C  C   . LEU A 1 142 ? 121.514 115.014 86.403  1.00 45.63  ? 89  LEU D C   1 
ATOM   643   O  O   . LEU A 1 142 ? 121.317 116.175 86.030  1.00 47.59  ? 89  LEU D O   1 
ATOM   644   C  CB  . LEU A 1 142 ? 123.942 114.806 86.971  1.00 48.82  ? 89  LEU D CB  1 
ATOM   645   C  CG  . LEU A 1 142 ? 124.470 113.826 85.924  1.00 48.12  ? 89  LEU D CG  1 
ATOM   646   C  CD1 . LEU A 1 142 ? 124.054 114.197 84.514  1.00 44.47  ? 89  LEU D CD1 1 
ATOM   647   C  CD2 . LEU A 1 142 ? 125.979 113.770 86.024  1.00 50.42  ? 89  LEU D CD2 1 
ATOM   648   N  N   . MET A 1 143 ? 120.882 113.970 85.865  1.00 44.68  ? 90  MET D N   1 
ATOM   649   C  CA  . MET A 1 143 ? 119.787 114.174 84.926  1.00 44.10  ? 90  MET D CA  1 
ATOM   650   C  C   . MET A 1 143 ? 118.676 115.002 85.555  1.00 46.66  ? 90  MET D C   1 
ATOM   651   O  O   . MET A 1 143 ? 117.934 115.690 84.848  1.00 48.26  ? 90  MET D O   1 
ATOM   652   C  CB  . MET A 1 143 ? 119.256 112.822 84.448  1.00 44.55  ? 90  MET D CB  1 
ATOM   653   C  CG  . MET A 1 143 ? 118.010 112.885 83.582  1.00 48.42  ? 90  MET D CG  1 
ATOM   654   S  SD  . MET A 1 143 ? 118.313 113.482 81.917  1.00 67.52  ? 90  MET D SD  1 
ATOM   655   C  CE  . MET A 1 143 ? 118.906 111.983 81.150  1.00 53.97  ? 90  MET D CE  1 
ATOM   656   N  N   . ALA A 1 144 ? 118.568 114.974 86.885  1.00 46.94  ? 91  ALA D N   1 
ATOM   657   C  CA  . ALA A 1 144 ? 117.579 115.790 87.571  1.00 43.10  ? 91  ALA D CA  1 
ATOM   658   C  C   . ALA A 1 144 ? 117.775 117.275 87.314  1.00 44.37  ? 91  ALA D C   1 
ATOM   659   O  O   . ALA A 1 144 ? 116.825 118.049 87.465  1.00 49.16  ? 91  ALA D O   1 
ATOM   660   C  CB  . ALA A 1 144 ? 117.623 115.515 89.070  1.00 40.90  ? 91  ALA D CB  1 
ATOM   661   N  N   . SER A 1 145 ? 118.974 117.697 86.933  1.00 45.16  ? 92  SER D N   1 
ATOM   662   C  CA  . SER A 1 145 ? 119.215 119.101 86.649  1.00 44.17  ? 92  SER D CA  1 
ATOM   663   C  C   . SER A 1 145 ? 118.924 119.469 85.202  1.00 43.00  ? 92  SER D C   1 
ATOM   664   O  O   . SER A 1 145 ? 119.033 120.643 84.844  1.00 44.27  ? 92  SER D O   1 
ATOM   665   C  CB  . SER A 1 145 ? 120.655 119.473 87.000  1.00 48.87  ? 92  SER D CB  1 
ATOM   666   O  OG  . SER A 1 145 ? 121.576 118.757 86.203  1.00 58.27  ? 92  SER D OG  1 
ATOM   667   N  N   . LYS A 1 146 ? 118.556 118.503 84.366  1.00 41.37  ? 93  LYS D N   1 
ATOM   668   C  CA  . LYS A 1 146 ? 118.226 118.777 82.978  1.00 42.28  ? 93  LYS D CA  1 
ATOM   669   C  C   . LYS A 1 146 ? 116.729 118.795 82.710  1.00 44.60  ? 93  LYS D C   1 
ATOM   670   O  O   . LYS A 1 146 ? 116.326 119.105 81.586  1.00 48.73  ? 93  LYS D O   1 
ATOM   671   C  CB  . LYS A 1 146 ? 118.881 117.740 82.058  1.00 45.77  ? 93  LYS D CB  1 
ATOM   672   C  CG  . LYS A 1 146 ? 120.370 117.547 82.271  1.00 44.91  ? 93  LYS D CG  1 
ATOM   673   C  CD  . LYS A 1 146 ? 121.157 118.743 81.796  1.00 52.77  ? 93  LYS D CD  1 
ATOM   674   C  CE  . LYS A 1 146 ? 122.622 118.631 82.179  1.00 55.60  ? 93  LYS D CE  1 
ATOM   675   N  NZ  . LYS A 1 146 ? 123.319 117.558 81.429  1.00 55.90  ? 93  LYS D NZ  1 
ATOM   676   N  N   . ILE A 1 147 ? 115.899 118.464 83.698  1.00 42.79  ? 94  ILE D N   1 
ATOM   677   C  CA  . ILE A 1 147 ? 114.452 118.431 83.516  1.00 42.36  ? 94  ILE D CA  1 
ATOM   678   C  C   . ILE A 1 147 ? 113.790 119.381 84.503  1.00 43.62  ? 94  ILE D C   1 
ATOM   679   O  O   . ILE A 1 147 ? 114.468 120.055 85.284  1.00 46.51  ? 94  ILE D O   1 
ATOM   680   C  CB  . ILE A 1 147 ? 113.893 117.008 83.681  1.00 38.00  ? 94  ILE D CB  1 
ATOM   681   C  CG1 . ILE A 1 147 ? 114.162 116.495 85.092  1.00 39.77  ? 94  ILE D CG1 1 
ATOM   682   C  CG2 . ILE A 1 147 ? 114.481 116.076 82.646  1.00 36.16  ? 94  ILE D CG2 1 
ATOM   683   C  CD1 . ILE A 1 147 ? 113.570 115.146 85.366  1.00 37.45  ? 94  ILE D CD1 1 
ATOM   684   N  N   . TRP A 1 148 ? 112.462 119.445 84.472  1.00 38.64  ? 95  TRP D N   1 
ATOM   685   C  CA  . TRP A 1 148 ? 111.708 120.277 85.398  1.00 36.08  ? 95  TRP D CA  1 
ATOM   686   C  C   . TRP A 1 148 ? 111.422 119.489 86.666  1.00 38.00  ? 95  TRP D C   1 
ATOM   687   O  O   . TRP A 1 148 ? 111.034 118.320 86.601  1.00 40.61  ? 95  TRP D O   1 
ATOM   688   C  CB  . TRP A 1 148 ? 110.398 120.751 84.766  1.00 35.74  ? 95  TRP D CB  1 
ATOM   689   C  CG  . TRP A 1 148 ? 109.626 121.692 85.640  1.00 36.82  ? 95  TRP D CG  1 
ATOM   690   C  CD1 . TRP A 1 148 ? 109.739 123.045 85.674  1.00 37.09  ? 95  TRP D CD1 1 
ATOM   691   C  CD2 . TRP A 1 148 ? 108.631 121.350 86.614  1.00 37.57  ? 95  TRP D CD2 1 
ATOM   692   N  NE1 . TRP A 1 148 ? 108.883 123.570 86.604  1.00 37.26  ? 95  TRP D NE1 1 
ATOM   693   C  CE2 . TRP A 1 148 ? 108.188 122.548 87.193  1.00 37.85  ? 95  TRP D CE2 1 
ATOM   694   C  CE3 . TRP A 1 148 ? 108.072 120.147 87.051  1.00 34.29  ? 95  TRP D CE3 1 
ATOM   695   C  CZ2 . TRP A 1 148 ? 107.215 122.580 88.184  1.00 38.19  ? 95  TRP D CZ2 1 
ATOM   696   C  CZ3 . TRP A 1 148 ? 107.104 120.184 88.033  1.00 31.28  ? 95  TRP D CZ3 1 
ATOM   697   C  CH2 . TRP A 1 148 ? 106.685 121.388 88.586  1.00 34.95  ? 95  TRP D CH2 1 
ATOM   698   N  N   . THR A 1 149 ? 111.615 120.128 87.812  1.00 36.99  ? 96  THR D N   1 
ATOM   699   C  CA  . THR A 1 149 ? 111.305 119.536 89.101  1.00 36.76  ? 96  THR D CA  1 
ATOM   700   C  C   . THR A 1 149 ? 110.540 120.544 89.943  1.00 37.38  ? 96  THR D C   1 
ATOM   701   O  O   . THR A 1 149 ? 110.672 121.754 89.737  1.00 35.75  ? 96  THR D O   1 
ATOM   702   C  CB  . THR A 1 149 ? 112.574 119.099 89.844  1.00 36.28  ? 96  THR D CB  1 
ATOM   703   O  OG1 . THR A 1 149 ? 113.501 120.187 89.894  1.00 45.52  ? 96  THR D OG1 1 
ATOM   704   C  CG2 . THR A 1 149 ? 113.222 117.921 89.149  1.00 30.65  ? 96  THR D CG2 1 
ATOM   705   N  N   . PRO A 1 150 ? 109.708 120.080 90.871  1.00 36.56  ? 97  PRO D N   1 
ATOM   706   C  CA  . PRO A 1 150 ? 109.004 121.011 91.753  1.00 36.95  ? 97  PRO D CA  1 
ATOM   707   C  C   . PRO A 1 150 ? 109.965 121.753 92.663  1.00 37.26  ? 97  PRO D C   1 
ATOM   708   O  O   . PRO A 1 150 ? 111.023 121.247 93.038  1.00 39.85  ? 97  PRO D O   1 
ATOM   709   C  CB  . PRO A 1 150 ? 108.072 120.102 92.558  1.00 31.92  ? 97  PRO D CB  1 
ATOM   710   C  CG  . PRO A 1 150 ? 107.943 118.885 91.750  1.00 31.80  ? 97  PRO D CG  1 
ATOM   711   C  CD  . PRO A 1 150 ? 109.261 118.698 91.087  1.00 32.94  ? 97  PRO D CD  1 
ATOM   712   N  N   . ASP A 1 151 ? 109.587 122.979 93.000  1.00 32.43  ? 98  ASP D N   1 
ATOM   713   C  CA  . ASP A 1 151 ? 110.349 123.803 93.934  1.00 28.32  ? 98  ASP D CA  1 
ATOM   714   C  C   . ASP A 1 151 ? 109.723 123.746 95.326  1.00 27.20  ? 98  ASP D C   1 
ATOM   715   O  O   . ASP A 1 151 ? 109.266 124.738 95.880  1.00 28.52  ? 98  ASP D O   1 
ATOM   716   C  CB  . ASP A 1 151 ? 110.434 125.233 93.417  1.00 34.42  ? 98  ASP D CB  1 
ATOM   717   C  CG  . ASP A 1 151 ? 109.088 125.796 93.066  1.00 37.77  ? 98  ASP D CG  1 
ATOM   718   O  OD1 . ASP A 1 151 ? 108.157 124.994 92.866  1.00 39.72  ? 98  ASP D OD1 1 
ATOM   719   O  OD2 . ASP A 1 151 ? 108.957 127.032 92.997  1.00 38.33  ? 98  ASP D OD2 1 
ATOM   720   N  N   . THR A 1 152 ? 109.710 122.542 95.885  1.00 29.03  ? 99  THR D N   1 
ATOM   721   C  CA  . THR A 1 152 ? 109.131 122.325 97.202  1.00 26.91  ? 99  THR D CA  1 
ATOM   722   C  C   . THR A 1 152 ? 110.050 122.879 98.285  1.00 25.83  ? 99  THR D C   1 
ATOM   723   O  O   . THR A 1 152 ? 111.272 122.750 98.208  1.00 31.41  ? 99  THR D O   1 
ATOM   724   C  CB  . THR A 1 152 ? 108.879 120.834 97.422  1.00 26.63  ? 99  THR D CB  1 
ATOM   725   O  OG1 . THR A 1 152 ? 107.970 120.357 96.426  1.00 26.20  ? 99  THR D OG1 1 
ATOM   726   C  CG2 . THR A 1 152 ? 108.272 120.582 98.775  1.00 22.67  ? 99  THR D CG2 1 
ATOM   727   N  N   . PHE A 1 153 ? 109.454 123.519 99.289  1.00 23.46  ? 100 PHE D N   1 
ATOM   728   C  CA  . PHE A 1 153 ? 110.208 124.064 100.406 1.00 21.36  ? 100 PHE D CA  1 
ATOM   729   C  C   . PHE A 1 153 ? 109.374 123.946 101.672 1.00 23.96  ? 100 PHE D C   1 
ATOM   730   O  O   . PHE A 1 153 ? 108.149 123.810 101.624 1.00 26.41  ? 100 PHE D O   1 
ATOM   731   C  CB  . PHE A 1 153 ? 110.615 125.518 100.150 1.00 22.38  ? 100 PHE D CB  1 
ATOM   732   C  CG  . PHE A 1 153 ? 109.576 126.524 100.538 1.00 22.97  ? 100 PHE D CG  1 
ATOM   733   C  CD1 . PHE A 1 153 ? 108.378 126.611 99.864  1.00 21.16  ? 100 PHE D CD1 1 
ATOM   734   C  CD2 . PHE A 1 153 ? 109.813 127.405 101.569 1.00 23.45  ? 100 PHE D CD2 1 
ATOM   735   C  CE1 . PHE A 1 153 ? 107.442 127.544 100.229 1.00 18.76  ? 100 PHE D CE1 1 
ATOM   736   C  CE2 . PHE A 1 153 ? 108.880 128.332 101.928 1.00 23.05  ? 100 PHE D CE2 1 
ATOM   737   C  CZ  . PHE A 1 153 ? 107.697 128.403 101.258 1.00 19.84  ? 100 PHE D CZ  1 
ATOM   738   N  N   . PHE A 1 154 ? 110.056 123.995 102.812 1.00 22.03  ? 101 PHE D N   1 
ATOM   739   C  CA  . PHE A 1 154 ? 109.430 123.811 104.115 1.00 21.32  ? 101 PHE D CA  1 
ATOM   740   C  C   . PHE A 1 154 ? 109.111 125.168 104.722 1.00 22.75  ? 101 PHE D C   1 
ATOM   741   O  O   . PHE A 1 154 ? 110.005 125.997 104.905 1.00 26.95  ? 101 PHE D O   1 
ATOM   742   C  CB  . PHE A 1 154 ? 110.336 122.998 105.034 1.00 20.56  ? 101 PHE D CB  1 
ATOM   743   C  CG  . PHE A 1 154 ? 110.684 121.655 104.482 1.00 21.48  ? 101 PHE D CG  1 
ATOM   744   C  CD1 . PHE A 1 154 ? 109.859 120.572 104.688 1.00 23.12  ? 101 PHE D CD1 1 
ATOM   745   C  CD2 . PHE A 1 154 ? 111.823 121.481 103.731 1.00 22.71  ? 101 PHE D CD2 1 
ATOM   746   C  CE1 . PHE A 1 154 ? 110.170 119.343 104.163 1.00 22.68  ? 101 PHE D CE1 1 
ATOM   747   C  CE2 . PHE A 1 154 ? 112.135 120.254 103.208 1.00 23.21  ? 101 PHE D CE2 1 
ATOM   748   C  CZ  . PHE A 1 154 ? 111.308 119.184 103.427 1.00 24.89  ? 101 PHE D CZ  1 
ATOM   749   N  N   . HIS A 1 155 ? 107.836 125.380 105.047 1.00 22.76  ? 102 HIS D N   1 
ATOM   750   C  CA  . HIS A 1 155 ? 107.374 126.703 105.452 1.00 22.55  ? 102 HIS D CA  1 
ATOM   751   C  C   . HIS A 1 155 ? 107.967 127.129 106.785 1.00 24.40  ? 102 HIS D C   1 
ATOM   752   O  O   . HIS A 1 155 ? 108.260 128.310 106.987 1.00 27.25  ? 102 HIS D O   1 
ATOM   753   C  CB  . HIS A 1 155 ? 105.854 126.726 105.518 1.00 26.23  ? 102 HIS D CB  1 
ATOM   754   C  CG  . HIS A 1 155 ? 105.196 126.602 104.185 1.00 25.91  ? 102 HIS D CG  1 
ATOM   755   N  ND1 . HIS A 1 155 ? 103.831 126.617 104.024 1.00 30.06  ? 102 HIS D ND1 1 
ATOM   756   C  CD2 . HIS A 1 155 ? 105.719 126.466 102.947 1.00 26.75  ? 102 HIS D CD2 1 
ATOM   757   C  CE1 . HIS A 1 155 ? 103.541 126.493 102.743 1.00 32.21  ? 102 HIS D CE1 1 
ATOM   758   N  NE2 . HIS A 1 155 ? 104.669 126.402 102.067 1.00 32.04  ? 102 HIS D NE2 1 
ATOM   759   N  N   . ASN A 1 156 ? 108.125 126.195 107.717 1.00 25.86  ? 103 ASN D N   1 
ATOM   760   C  CA  . ASN A 1 156 ? 108.709 126.500 109.013 1.00 25.48  ? 103 ASN D CA  1 
ATOM   761   C  C   . ASN A 1 156 ? 110.156 126.050 109.128 1.00 26.82  ? 103 ASN D C   1 
ATOM   762   O  O   . ASN A 1 156 ? 110.691 126.021 110.235 1.00 32.97  ? 103 ASN D O   1 
ATOM   763   C  CB  . ASN A 1 156 ? 107.879 125.875 110.133 1.00 26.24  ? 103 ASN D CB  1 
ATOM   764   C  CG  . ASN A 1 156 ? 107.845 124.378 110.058 1.00 27.94  ? 103 ASN D CG  1 
ATOM   765   O  OD1 . ASN A 1 156 ? 107.850 123.807 108.976 1.00 29.29  ? 103 ASN D OD1 1 
ATOM   766   N  ND2 . ASN A 1 156 ? 107.810 123.730 111.208 1.00 28.89  ? 103 ASN D ND2 1 
ATOM   767   N  N   . GLY A 1 157 ? 110.797 125.690 108.021 1.00 23.45  ? 104 GLY D N   1 
ATOM   768   C  CA  . GLY A 1 157 ? 112.193 125.313 108.078 1.00 25.25  ? 104 GLY D CA  1 
ATOM   769   C  C   . GLY A 1 157 ? 113.083 126.492 108.419 1.00 26.47  ? 104 GLY D C   1 
ATOM   770   O  O   . GLY A 1 157 ? 112.807 127.635 108.065 1.00 32.08  ? 104 GLY D O   1 
ATOM   771   N  N   . LYS A 1 158 ? 114.181 126.202 109.113 1.00 26.94  ? 105 LYS D N   1 
ATOM   772   C  CA  . LYS A 1 158 ? 115.090 127.228 109.605 1.00 28.11  ? 105 LYS D CA  1 
ATOM   773   C  C   . LYS A 1 158 ? 116.429 127.214 108.882 1.00 29.03  ? 105 LYS D C   1 
ATOM   774   O  O   . LYS A 1 158 ? 116.882 128.254 108.405 1.00 40.27  ? 105 LYS D O   1 
ATOM   775   C  CB  . LYS A 1 158 ? 115.293 127.067 111.115 1.00 30.65  ? 105 LYS D CB  1 
ATOM   776   C  CG  . LYS A 1 158 ? 114.079 127.471 111.922 1.00 35.69  ? 105 LYS D CG  1 
ATOM   777   C  CD  . LYS A 1 158 ? 114.294 127.300 113.409 1.00 35.74  ? 105 LYS D CD  1 
ATOM   778   C  CE  . LYS A 1 158 ? 115.315 128.273 113.932 1.00 40.71  ? 105 LYS D CE  1 
ATOM   779   N  NZ  . LYS A 1 158 ? 115.386 128.240 115.412 1.00 41.29  ? 105 LYS D NZ  1 
ATOM   780   N  N   . LYS A 1 159 ? 117.089 126.063 108.804 1.00 27.63  ? 106 LYS D N   1 
ATOM   781   C  CA  . LYS A 1 159 ? 118.340 125.940 108.060 1.00 29.25  ? 106 LYS D CA  1 
ATOM   782   C  C   . LYS A 1 159 ? 118.536 124.457 107.774 1.00 29.58  ? 106 LYS D C   1 
ATOM   783   O  O   . LYS A 1 159 ? 118.962 123.705 108.653 1.00 33.26  ? 106 LYS D O   1 
ATOM   784   C  CB  . LYS A 1 159 ? 119.509 126.522 108.843 1.00 32.71  ? 106 LYS D CB  1 
ATOM   785   C  CG  . LYS A 1 159 ? 120.871 126.280 108.227 1.00 34.48  ? 106 LYS D CG  1 
ATOM   786   C  CD  . LYS A 1 159 ? 121.113 127.153 107.020 1.00 35.41  ? 106 LYS D CD  1 
ATOM   787   C  CE  . LYS A 1 159 ? 122.506 126.932 106.464 1.00 40.42  ? 106 LYS D CE  1 
ATOM   788   N  NZ  . LYS A 1 159 ? 122.752 127.729 105.233 1.00 48.50  ? 106 LYS D NZ  1 
ATOM   789   N  N   . SER A 1 160 ? 118.232 124.049 106.552 1.00 29.65  ? 107 SER D N   1 
ATOM   790   C  CA  . SER A 1 160 ? 118.237 122.648 106.174 1.00 27.33  ? 107 SER D CA  1 
ATOM   791   C  C   . SER A 1 160 ? 119.495 122.297 105.392 1.00 28.56  ? 107 SER D C   1 
ATOM   792   O  O   . SER A 1 160 ? 120.239 123.163 104.933 1.00 33.41  ? 107 SER D O   1 
ATOM   793   C  CB  . SER A 1 160 ? 116.989 122.318 105.356 1.00 28.99  ? 107 SER D CB  1 
ATOM   794   O  OG  . SER A 1 160 ? 115.822 122.738 106.034 1.00 32.56  ? 107 SER D OG  1 
ATOM   795   N  N   . VAL A 1 161 ? 119.725 120.997 105.243 1.00 29.84  ? 108 VAL D N   1 
ATOM   796   C  CA  . VAL A 1 161 ? 120.892 120.470 104.550 1.00 25.51  ? 108 VAL D CA  1 
ATOM   797   C  C   . VAL A 1 161 ? 120.436 119.439 103.530 1.00 26.34  ? 108 VAL D C   1 
ATOM   798   O  O   . VAL A 1 161 ? 119.717 118.498 103.874 1.00 26.39  ? 108 VAL D O   1 
ATOM   799   C  CB  . VAL A 1 161 ? 121.895 119.839 105.532 1.00 23.57  ? 108 VAL D CB  1 
ATOM   800   C  CG1 . VAL A 1 161 ? 122.932 119.043 104.787 1.00 24.70  ? 108 VAL D CG1 1 
ATOM   801   C  CG2 . VAL A 1 161 ? 122.556 120.906 106.367 1.00 26.98  ? 108 VAL D CG2 1 
ATOM   802   N  N   . ALA A 1 162 ? 120.857 119.615 102.284 1.00 25.47  ? 109 ALA D N   1 
ATOM   803   C  CA  . ALA A 1 162 ? 120.697 118.607 101.241 1.00 23.06  ? 109 ALA D CA  1 
ATOM   804   C  C   . ALA A 1 162 ? 122.050 117.928 101.073 1.00 26.42  ? 109 ALA D C   1 
ATOM   805   O  O   . ALA A 1 162 ? 122.964 118.491 100.470 1.00 34.72  ? 109 ALA D O   1 
ATOM   806   C  CB  . ALA A 1 162 ? 120.217 119.236 99.941  1.00 18.90  ? 109 ALA D CB  1 
ATOM   807   N  N   . HIS A 1 163 ? 122.168 116.712 101.597 1.00 21.90  ? 110 HIS D N   1 
ATOM   808   C  CA  . HIS A 1 163 ? 123.469 116.079 101.762 1.00 23.64  ? 110 HIS D CA  1 
ATOM   809   C  C   . HIS A 1 163 ? 124.134 115.783 100.424 1.00 29.57  ? 110 HIS D C   1 
ATOM   810   O  O   . HIS A 1 163 ? 123.495 115.315 99.481  1.00 31.39  ? 110 HIS D O   1 
ATOM   811   C  CB  . HIS A 1 163 ? 123.320 114.801 102.571 1.00 23.54  ? 110 HIS D CB  1 
ATOM   812   C  CG  . HIS A 1 163 ? 122.758 115.025 103.936 1.00 25.61  ? 110 HIS D CG  1 
ATOM   813   N  ND1 . HIS A 1 163 ? 123.549 115.271 105.036 1.00 25.53  ? 110 HIS D ND1 1 
ATOM   814   C  CD2 . HIS A 1 163 ? 121.482 115.054 104.378 1.00 26.29  ? 110 HIS D CD2 1 
ATOM   815   C  CE1 . HIS A 1 163 ? 122.784 115.429 106.098 1.00 23.15  ? 110 HIS D CE1 1 
ATOM   816   N  NE2 . HIS A 1 163 ? 121.525 115.303 105.727 1.00 25.97  ? 110 HIS D NE2 1 
ATOM   817   N  N   . ASN A 1 164 ? 125.439 116.054 100.357 1.00 30.21  ? 111 ASN D N   1 
ATOM   818   C  CA  . ASN A 1 164 ? 126.196 116.015 99.113  1.00 30.05  ? 111 ASN D CA  1 
ATOM   819   C  C   . ASN A 1 164 ? 127.400 115.083 99.192  1.00 34.98  ? 111 ASN D C   1 
ATOM   820   O  O   . ASN A 1 164 ? 128.350 115.248 98.425  1.00 40.78  ? 111 ASN D O   1 
ATOM   821   C  CB  . ASN A 1 164 ? 126.649 117.427 98.737  1.00 34.63  ? 111 ASN D CB  1 
ATOM   822   C  CG  . ASN A 1 164 ? 126.716 117.643 97.244  1.00 45.57  ? 111 ASN D CG  1 
ATOM   823   O  OD1 . ASN A 1 164 ? 125.774 117.333 96.528  1.00 50.24  ? 111 ASN D OD1 1 
ATOM   824   N  ND2 . ASN A 1 164 ? 127.831 118.177 96.765  1.00 51.11  ? 111 ASN D ND2 1 
ATOM   825   N  N   . MET A 1 165 ? 127.380 114.104 100.093 1.00 34.51  ? 112 MET D N   1 
ATOM   826   C  CA  . MET A 1 165 ? 128.497 113.194 100.314 1.00 33.49  ? 112 MET D CA  1 
ATOM   827   C  C   . MET A 1 165 ? 128.017 111.758 100.176 1.00 30.03  ? 112 MET D C   1 
ATOM   828   O  O   . MET A 1 165 ? 127.017 111.384 100.792 1.00 32.79  ? 112 MET D O   1 
ATOM   829   C  CB  . MET A 1 165 ? 129.096 113.418 101.700 1.00 32.20  ? 112 MET D CB  1 
ATOM   830   C  CG  . MET A 1 165 ? 129.943 112.281 102.222 1.00 34.26  ? 112 MET D CG  1 
ATOM   831   S  SD  . MET A 1 165 ? 131.646 112.382 101.672 1.00 51.72  ? 112 MET D SD  1 
ATOM   832   C  CE  . MET A 1 165 ? 131.881 114.148 101.686 1.00 38.75  ? 112 MET D CE  1 
ATOM   833   N  N   . THR A 1 166 ? 128.719 110.952 99.377  1.00 27.98  ? 113 THR D N   1 
ATOM   834   C  CA  . THR A 1 166 ? 129.884 111.372 98.604  1.00 28.38  ? 113 THR D CA  1 
ATOM   835   C  C   . THR A 1 166 ? 129.478 112.033 97.296  1.00 32.88  ? 113 THR D C   1 
ATOM   836   O  O   . THR A 1 166 ? 130.276 112.705 96.653  1.00 36.75  ? 113 THR D O   1 
ATOM   837   C  CB  . THR A 1 166 ? 130.804 110.183 98.283  1.00 27.95  ? 113 THR D CB  1 
ATOM   838   O  OG1 . THR A 1 166 ? 130.115 109.256 97.440  1.00 32.07  ? 113 THR D OG1 1 
ATOM   839   C  CG2 . THR A 1 166 ? 131.225 109.475 99.545  1.00 26.36  ? 113 THR D CG2 1 
ATOM   840   N  N   . MET A 1 167 ? 128.227 111.836 96.918  1.00 33.53  ? 114 MET D N   1 
ATOM   841   C  CA  . MET A 1 167 ? 127.597 112.431 95.753  1.00 33.67  ? 114 MET D CA  1 
ATOM   842   C  C   . MET A 1 167 ? 126.273 113.022 96.202  1.00 35.77  ? 114 MET D C   1 
ATOM   843   O  O   . MET A 1 167 ? 125.794 112.712 97.296  1.00 39.73  ? 114 MET D O   1 
ATOM   844   C  CB  . MET A 1 167 ? 127.367 111.388 94.649  1.00 33.72  ? 114 MET D CB  1 
ATOM   845   C  CG  . MET A 1 167 ? 128.624 110.703 94.153  1.00 41.24  ? 114 MET D CG  1 
ATOM   846   S  SD  . MET A 1 167 ? 129.830 111.829 93.422  1.00 66.34  ? 114 MET D SD  1 
ATOM   847   C  CE  . MET A 1 167 ? 128.938 112.419 91.992  1.00 43.55  ? 114 MET D CE  1 
ATOM   848   N  N   . PRO A 1 168 ? 125.670 113.907 95.403  1.00 35.33  ? 115 PRO D N   1 
ATOM   849   C  CA  . PRO A 1 168 ? 124.331 114.403 95.745  1.00 31.68  ? 115 PRO D CA  1 
ATOM   850   C  C   . PRO A 1 168 ? 123.349 113.277 96.032  1.00 32.97  ? 115 PRO D C   1 
ATOM   851   O  O   . PRO A 1 168 ? 123.050 112.466 95.154  1.00 33.57  ? 115 PRO D O   1 
ATOM   852   C  CB  . PRO A 1 168 ? 123.930 115.195 94.498  1.00 30.34  ? 115 PRO D CB  1 
ATOM   853   C  CG  . PRO A 1 168 ? 125.195 115.619 93.910  1.00 34.72  ? 115 PRO D CG  1 
ATOM   854   C  CD  . PRO A 1 168 ? 126.198 114.556 94.193  1.00 37.31  ? 115 PRO D CD  1 
ATOM   855   N  N   . ASN A 1 169 ? 122.843 113.215 97.263  1.00 30.60  ? 116 ASN D N   1 
ATOM   856   C  CA  . ASN A 1 169 ? 121.967 112.125 97.692  1.00 25.68  ? 116 ASN D CA  1 
ATOM   857   C  C   . ASN A 1 169 ? 120.587 112.335 97.081  1.00 26.71  ? 116 ASN D C   1 
ATOM   858   O  O   . ASN A 1 169 ? 119.649 112.813 97.721  1.00 27.60  ? 116 ASN D O   1 
ATOM   859   C  CB  . ASN A 1 169 ? 121.890 112.049 99.210  1.00 22.14  ? 116 ASN D CB  1 
ATOM   860   C  CG  . ASN A 1 169 ? 123.199 111.648 99.843  1.00 23.88  ? 116 ASN D CG  1 
ATOM   861   O  OD1 . ASN A 1 169 ? 123.322 111.616 101.060 1.00 26.07  ? 116 ASN D OD1 1 
ATOM   862   N  ND2 . ASN A 1 169 ? 124.187 111.352 99.022  1.00 26.74  ? 116 ASN D ND2 1 
ATOM   863   N  N   . LYS A 1 170 ? 120.472 111.980 95.807  1.00 25.38  ? 117 LYS D N   1 
ATOM   864   C  CA  . LYS A 1 170 ? 119.217 112.041 95.083  1.00 24.80  ? 117 LYS D CA  1 
ATOM   865   C  C   . LYS A 1 170 ? 119.131 110.845 94.153  1.00 26.87  ? 117 LYS D C   1 
ATOM   866   O  O   . LYS A 1 170 ? 120.148 110.303 93.720  1.00 29.09  ? 117 LYS D O   1 
ATOM   867   C  CB  . LYS A 1 170 ? 119.082 113.330 94.268  1.00 26.39  ? 117 LYS D CB  1 
ATOM   868   C  CG  . LYS A 1 170 ? 119.035 114.586 95.093  1.00 26.50  ? 117 LYS D CG  1 
ATOM   869   C  CD  . LYS A 1 170 ? 119.087 115.809 94.219  1.00 24.53  ? 117 LYS D CD  1 
ATOM   870   C  CE  . LYS A 1 170 ? 119.034 117.064 95.054  1.00 33.91  ? 117 LYS D CE  1 
ATOM   871   N  NZ  . LYS A 1 170 ? 119.056 118.280 94.205  1.00 48.30  ? 117 LYS D NZ  1 
ATOM   872   N  N   . LEU A 1 171 ? 117.905 110.440 93.854  1.00 26.60  ? 118 LEU D N   1 
ATOM   873   C  CA  . LEU A 1 171 ? 117.651 109.414 92.857  1.00 27.81  ? 118 LEU D CA  1 
ATOM   874   C  C   . LEU A 1 171 ? 116.553 109.886 91.922  1.00 28.24  ? 118 LEU D C   1 
ATOM   875   O  O   . LEU A 1 171 ? 115.573 110.499 92.360  1.00 31.75  ? 118 LEU D O   1 
ATOM   876   C  CB  . LEU A 1 171 ? 117.273 108.070 93.500  1.00 27.29  ? 118 LEU D CB  1 
ATOM   877   C  CG  . LEU A 1 171 ? 115.903 107.820 94.124  1.00 25.79  ? 118 LEU D CG  1 
ATOM   878   C  CD1 . LEU A 1 171 ? 114.924 107.288 93.102  1.00 26.55  ? 118 LEU D CD1 1 
ATOM   879   C  CD2 . LEU A 1 171 ? 116.037 106.846 95.265  1.00 26.15  ? 118 LEU D CD2 1 
ATOM   880   N  N   . LEU A 1 172 ? 116.727 109.591 90.636  1.00 28.90  ? 119 LEU D N   1 
ATOM   881   C  CA  . LEU A 1 172 ? 115.766 109.929 89.598  1.00 31.35  ? 119 LEU D CA  1 
ATOM   882   C  C   . LEU A 1 172 ? 115.428 108.679 88.800  1.00 37.10  ? 119 LEU D C   1 
ATOM   883   O  O   . LEU A 1 172 ? 116.326 107.942 88.374  1.00 41.52  ? 119 LEU D O   1 
ATOM   884   C  CB  . LEU A 1 172 ? 116.307 111.014 88.669  1.00 32.54  ? 119 LEU D CB  1 
ATOM   885   C  CG  . LEU A 1 172 ? 115.316 111.499 87.614  1.00 35.94  ? 119 LEU D CG  1 
ATOM   886   C  CD1 . LEU A 1 172 ? 114.223 112.333 88.246  1.00 34.43  ? 119 LEU D CD1 1 
ATOM   887   C  CD2 . LEU A 1 172 ? 116.025 112.284 86.542  1.00 41.17  ? 119 LEU D CD2 1 
ATOM   888   N  N   . ARG A 1 173 ? 114.135 108.441 88.610  1.00 35.82  ? 120 ARG D N   1 
ATOM   889   C  CA  . ARG A 1 173 ? 113.647 107.314 87.835  1.00 34.32  ? 120 ARG D CA  1 
ATOM   890   C  C   . ARG A 1 173 ? 112.558 107.785 86.888  1.00 37.26  ? 120 ARG D C   1 
ATOM   891   O  O   . ARG A 1 173 ? 111.665 108.539 87.281  1.00 40.29  ? 120 ARG D O   1 
ATOM   892   C  CB  . ARG A 1 173 ? 113.112 106.210 88.740  1.00 31.58  ? 120 ARG D CB  1 
ATOM   893   C  CG  . ARG A 1 173 ? 114.191 105.524 89.524  1.00 34.88  ? 120 ARG D CG  1 
ATOM   894   C  CD  . ARG A 1 173 ? 113.634 104.561 90.534  1.00 36.61  ? 120 ARG D CD  1 
ATOM   895   N  NE  . ARG A 1 173 ? 114.687 104.067 91.408  1.00 37.92  ? 120 ARG D NE  1 
ATOM   896   C  CZ  . ARG A 1 173 ? 114.486 103.279 92.452  1.00 37.63  ? 120 ARG D CZ  1 
ATOM   897   N  NH1 . ARG A 1 173 ? 113.276 102.870 92.786  1.00 39.48  ? 120 ARG D NH1 1 
ATOM   898   N  NH2 . ARG A 1 173 ? 115.527 102.894 93.180  1.00 35.72  ? 120 ARG D NH2 1 
ATOM   899   N  N   . ILE A 1 174 ? 112.633 107.319 85.645  1.00 39.04  ? 121 ILE D N   1 
ATOM   900   C  CA  . ILE A 1 174 ? 111.692 107.687 84.592  1.00 37.36  ? 121 ILE D CA  1 
ATOM   901   C  C   . ILE A 1 174 ? 110.991 106.426 84.114  1.00 43.37  ? 121 ILE D C   1 
ATOM   902   O  O   . ILE A 1 174 ? 111.647 105.467 83.700  1.00 51.32  ? 121 ILE D O   1 
ATOM   903   C  CB  . ILE A 1 174 ? 112.394 108.383 83.420  1.00 35.78  ? 121 ILE D CB  1 
ATOM   904   C  CG1 . ILE A 1 174 ? 113.196 109.579 83.918  1.00 34.96  ? 121 ILE D CG1 1 
ATOM   905   C  CG2 . ILE A 1 174 ? 111.384 108.814 82.386  1.00 38.56  ? 121 ILE D CG2 1 
ATOM   906   C  CD1 . ILE A 1 174 ? 113.950 110.300 82.834  1.00 35.75  ? 121 ILE D CD1 1 
ATOM   907   N  N   . THR A 1 175 ? 109.667 106.429 84.152  1.00 40.86  ? 122 THR D N   1 
ATOM   908   C  CA  . THR A 1 175 ? 108.889 105.321 83.627  1.00 43.53  ? 122 THR D CA  1 
ATOM   909   C  C   . THR A 1 175 ? 108.529 105.584 82.166  1.00 49.44  ? 122 THR D C   1 
ATOM   910   O  O   . THR A 1 175 ? 108.583 106.715 81.684  1.00 55.01  ? 122 THR D O   1 
ATOM   911   C  CB  . THR A 1 175 ? 107.632 105.109 84.469  1.00 48.25  ? 122 THR D CB  1 
ATOM   912   O  OG1 . THR A 1 175 ? 107.974 105.218 85.854  1.00 51.64  ? 122 THR D OG1 1 
ATOM   913   C  CG2 . THR A 1 175 ? 107.050 103.730 84.239  1.00 53.27  ? 122 THR D CG2 1 
ATOM   914   N  N   . GLU A 1 176 ? 108.166 104.514 81.457  1.00 50.67  ? 123 GLU D N   1 
ATOM   915   C  CA  . GLU A 1 176 ? 107.937 104.611 80.020  1.00 52.61  ? 123 GLU D CA  1 
ATOM   916   C  C   . GLU A 1 176 ? 106.747 105.490 79.663  1.00 55.06  ? 123 GLU D C   1 
ATOM   917   O  O   . GLU A 1 176 ? 106.640 105.916 78.511  1.00 57.21  ? 123 GLU D O   1 
ATOM   918   C  CB  . GLU A 1 176 ? 107.744 103.220 79.426  1.00 55.62  ? 123 GLU D CB  1 
ATOM   919   C  CG  . GLU A 1 176 ? 106.575 102.474 80.014  1.00 62.37  ? 123 GLU D CG  1 
ATOM   920   C  CD  . GLU A 1 176 ? 106.347 101.138 79.348  1.00 72.23  ? 123 GLU D CD  1 
ATOM   921   O  OE1 . GLU A 1 176 ? 107.116 100.798 78.426  1.00 77.43  ? 123 GLU D OE1 1 
ATOM   922   O  OE2 . GLU A 1 176 ? 105.400 100.428 79.744  1.00 73.14  ? 123 GLU D OE2 1 
ATOM   923   N  N   . ASP A 1 177 ? 105.855 105.766 80.606  1.00 57.16  ? 124 ASP D N   1 
ATOM   924   C  CA  . ASP A 1 177 ? 104.713 106.633 80.351  1.00 55.27  ? 124 ASP D CA  1 
ATOM   925   C  C   . ASP A 1 177 ? 104.985 108.089 80.699  1.00 54.61  ? 124 ASP D C   1 
ATOM   926   O  O   . ASP A 1 177 ? 104.078 108.917 80.585  1.00 55.55  ? 124 ASP D O   1 
ATOM   927   C  CB  . ASP A 1 177 ? 103.494 106.149 81.133  1.00 54.95  ? 124 ASP D CB  1 
ATOM   928   C  CG  . ASP A 1 177 ? 103.624 106.392 82.619  1.00 57.83  ? 124 ASP D CG  1 
ATOM   929   O  OD1 . ASP A 1 177 ? 104.759 106.365 83.132  1.00 55.66  ? 124 ASP D OD1 1 
ATOM   930   O  OD2 . ASP A 1 177 ? 102.592 106.611 83.280  1.00 59.57  ? 124 ASP D OD2 1 
ATOM   931   N  N   . GLY A 1 178 ? 106.200 108.418 81.126  1.00 50.05  ? 125 GLY D N   1 
ATOM   932   C  CA  . GLY A 1 178 ? 106.537 109.767 81.518  1.00 48.27  ? 125 GLY D CA  1 
ATOM   933   C  C   . GLY A 1 178 ? 106.485 110.040 83.003  1.00 47.01  ? 125 GLY D C   1 
ATOM   934   O  O   . GLY A 1 178 ? 106.703 111.184 83.408  1.00 50.69  ? 125 GLY D O   1 
ATOM   935   N  N   . THR A 1 179 ? 106.187 109.040 83.823  1.00 42.59  ? 126 THR D N   1 
ATOM   936   C  CA  . THR A 1 179 ? 106.166 109.243 85.263  1.00 41.51  ? 126 THR D CA  1 
ATOM   937   C  C   . THR A 1 179 ? 107.581 109.440 85.793  1.00 40.75  ? 126 THR D C   1 
ATOM   938   O  O   . THR A 1 179 ? 108.522 108.777 85.358  1.00 45.71  ? 126 THR D O   1 
ATOM   939   C  CB  . THR A 1 179 ? 105.502 108.056 85.952  1.00 43.08  ? 126 THR D CB  1 
ATOM   940   O  OG1 . THR A 1 179 ? 104.191 107.872 85.415  1.00 50.95  ? 126 THR D OG1 1 
ATOM   941   C  CG2 . THR A 1 179 ? 105.386 108.308 87.432  1.00 39.86  ? 126 THR D CG2 1 
ATOM   942   N  N   . LEU A 1 180 ? 107.733 110.363 86.733  1.00 35.74  ? 127 LEU D N   1 
ATOM   943   C  CA  . LEU A 1 180 ? 109.020 110.671 87.330  1.00 32.55  ? 127 LEU D CA  1 
ATOM   944   C  C   . LEU A 1 180 ? 108.940 110.428 88.824  1.00 32.26  ? 127 LEU D C   1 
ATOM   945   O  O   . LEU A 1 180 ? 108.024 110.932 89.486  1.00 34.46  ? 127 LEU D O   1 
ATOM   946   C  CB  . LEU A 1 180 ? 109.421 112.120 87.061  1.00 28.63  ? 127 LEU D CB  1 
ATOM   947   C  CG  . LEU A 1 180 ? 109.490 112.537 85.601  1.00 33.44  ? 127 LEU D CG  1 
ATOM   948   C  CD1 . LEU A 1 180 ? 110.054 113.919 85.490  1.00 38.18  ? 127 LEU D CD1 1 
ATOM   949   C  CD2 . LEU A 1 180 ? 110.354 111.570 84.857  1.00 38.96  ? 127 LEU D CD2 1 
ATOM   950   N  N   . LEU A 1 181 ? 109.887 109.648 89.337  1.00 31.09  ? 128 LEU D N   1 
ATOM   951   C  CA  . LEU A 1 181 ? 110.122 109.511 90.766  1.00 29.25  ? 128 LEU D CA  1 
ATOM   952   C  C   . LEU A 1 181 ? 111.432 110.204 91.105  1.00 31.01  ? 128 LEU D C   1 
ATOM   953   O  O   . LEU A 1 181 ? 112.469 109.900 90.511  1.00 34.95  ? 128 LEU D O   1 
ATOM   954   C  CB  . LEU A 1 181 ? 110.176 108.045 91.190  1.00 29.09  ? 128 LEU D CB  1 
ATOM   955   C  CG  . LEU A 1 181 ? 110.354 107.824 92.689  1.00 28.49  ? 128 LEU D CG  1 
ATOM   956   C  CD1 . LEU A 1 181 ? 109.236 108.489 93.455  1.00 28.22  ? 128 LEU D CD1 1 
ATOM   957   C  CD2 . LEU A 1 181 ? 110.393 106.353 93.000  1.00 27.22  ? 128 LEU D CD2 1 
ATOM   958   N  N   . TYR A 1 182 ? 111.379 111.132 92.053  1.00 26.21  ? 129 TYR D N   1 
ATOM   959   C  CA  . TYR A 1 182 ? 112.521 111.966 92.394  1.00 24.23  ? 129 TYR D CA  1 
ATOM   960   C  C   . TYR A 1 182 ? 112.613 112.033 93.908  1.00 25.78  ? 129 TYR D C   1 
ATOM   961   O  O   . TYR A 1 182 ? 111.692 112.528 94.564  1.00 30.31  ? 129 TYR D O   1 
ATOM   962   C  CB  . TYR A 1 182 ? 112.359 113.353 91.773  1.00 25.84  ? 129 TYR D CB  1 
ATOM   963   C  CG  . TYR A 1 182 ? 113.423 114.354 92.111  1.00 28.80  ? 129 TYR D CG  1 
ATOM   964   C  CD1 . TYR A 1 182 ? 114.750 114.118 91.808  1.00 27.75  ? 129 TYR D CD1 1 
ATOM   965   C  CD2 . TYR A 1 182 ? 113.090 115.559 92.701  1.00 30.55  ? 129 TYR D CD2 1 
ATOM   966   C  CE1 . TYR A 1 182 ? 115.717 115.045 92.109  1.00 27.26  ? 129 TYR D CE1 1 
ATOM   967   C  CE2 . TYR A 1 182 ? 114.045 116.488 92.999  1.00 30.40  ? 129 TYR D CE2 1 
ATOM   968   C  CZ  . TYR A 1 182 ? 115.357 116.228 92.706  1.00 29.13  ? 129 TYR D CZ  1 
ATOM   969   O  OH  . TYR A 1 182 ? 116.315 117.163 93.002  1.00 29.64  ? 129 TYR D OH  1 
ATOM   970   N  N   . THR A 1 183 ? 113.703 111.518 94.462  1.00 25.56  ? 130 THR D N   1 
ATOM   971   C  CA  . THR A 1 183 ? 113.826 111.369 95.905  1.00 23.55  ? 130 THR D CA  1 
ATOM   972   C  C   . THR A 1 183 ? 115.138 111.964 96.382  1.00 22.56  ? 130 THR D C   1 
ATOM   973   O  O   . THR A 1 183 ? 116.162 111.823 95.713  1.00 27.05  ? 130 THR D O   1 
ATOM   974   C  CB  . THR A 1 183 ? 113.747 109.899 96.308  1.00 29.45  ? 130 THR D CB  1 
ATOM   975   O  OG1 . THR A 1 183 ? 112.551 109.322 95.776  1.00 29.26  ? 130 THR D OG1 1 
ATOM   976   C  CG2 . THR A 1 183 ? 113.732 109.764 97.803  1.00 26.95  ? 130 THR D CG2 1 
ATOM   977   N  N   . MET A 1 184 ? 115.108 112.625 97.538  1.00 21.78  ? 131 MET D N   1 
ATOM   978   C  CA  . MET A 1 184 ? 116.312 113.230 98.090  1.00 22.36  ? 131 MET D CA  1 
ATOM   979   C  C   . MET A 1 184 ? 116.392 113.001 99.591  1.00 23.35  ? 131 MET D C   1 
ATOM   980   O  O   . MET A 1 184 ? 115.378 112.834 100.265 1.00 27.28  ? 131 MET D O   1 
ATOM   981   C  CB  . MET A 1 184 ? 116.372 114.727 97.805  1.00 21.98  ? 131 MET D CB  1 
ATOM   982   C  CG  . MET A 1 184 ? 115.166 115.482 98.278  1.00 24.13  ? 131 MET D CG  1 
ATOM   983   S  SD  . MET A 1 184 ? 115.306 117.236 97.957  1.00 43.08  ? 131 MET D SD  1 
ATOM   984   C  CE  . MET A 1 184 ? 115.310 117.224 96.179  1.00 25.20  ? 131 MET D CE  1 
ATOM   985   N  N   . ARG A 1 185 ? 117.613 113.006 100.111 1.00 24.69  ? 132 ARG D N   1 
ATOM   986   C  CA  . ARG A 1 185 ? 117.859 112.872 101.539 1.00 23.31  ? 132 ARG D CA  1 
ATOM   987   C  C   . ARG A 1 185 ? 118.148 114.243 102.132 1.00 21.20  ? 132 ARG D C   1 
ATOM   988   O  O   . ARG A 1 185 ? 119.032 114.956 101.651 1.00 24.47  ? 132 ARG D O   1 
ATOM   989   C  CB  . ARG A 1 185 ? 119.026 111.922 101.803 1.00 21.98  ? 132 ARG D CB  1 
ATOM   990   C  CG  . ARG A 1 185 ? 119.404 111.814 103.252 1.00 19.41  ? 132 ARG D CG  1 
ATOM   991   C  CD  . ARG A 1 185 ? 120.413 110.716 103.487 1.00 19.77  ? 132 ARG D CD  1 
ATOM   992   N  NE  . ARG A 1 185 ? 121.104 110.907 104.754 1.00 26.44  ? 132 ARG D NE  1 
ATOM   993   C  CZ  . ARG A 1 185 ? 122.339 111.371 104.870 1.00 29.16  ? 132 ARG D CZ  1 
ATOM   994   N  NH1 . ARG A 1 185 ? 123.080 111.633 103.810 1.00 24.96  ? 132 ARG D NH1 1 
ATOM   995   N  NH2 . ARG A 1 185 ? 122.846 111.569 106.081 1.00 29.36  ? 132 ARG D NH2 1 
ATOM   996   N  N   . LEU A 1 186 ? 117.407 114.606 103.176 1.00 20.45  ? 133 LEU D N   1 
ATOM   997   C  CA  . LEU A 1 186 ? 117.450 115.948 103.734 1.00 20.33  ? 133 LEU D CA  1 
ATOM   998   C  C   . LEU A 1 186 ? 117.566 115.894 105.249 1.00 22.33  ? 133 LEU D C   1 
ATOM   999   O  O   . LEU A 1 186 ? 117.188 114.912 105.889 1.00 26.73  ? 133 LEU D O   1 
ATOM   1000  C  CB  . LEU A 1 186 ? 116.196 116.751 103.367 1.00 20.41  ? 133 LEU D CB  1 
ATOM   1001  C  CG  . LEU A 1 186 ? 115.851 116.979 101.899 1.00 20.93  ? 133 LEU D CG  1 
ATOM   1002  C  CD1 . LEU A 1 186 ? 114.532 117.690 101.785 1.00 20.75  ? 133 LEU D CD1 1 
ATOM   1003  C  CD2 . LEU A 1 186 ? 116.928 117.793 101.240 1.00 21.63  ? 133 LEU D CD2 1 
ATOM   1004  N  N   . THR A 1 187 ? 118.090 116.977 105.812 1.00 22.90  ? 134 THR D N   1 
ATOM   1005  C  CA  . THR A 1 187 ? 118.023 117.258 107.240 1.00 26.10  ? 134 THR D CA  1 
ATOM   1006  C  C   . THR A 1 187 ? 117.374 118.619 107.414 1.00 29.09  ? 134 THR D C   1 
ATOM   1007  O  O   . THR A 1 187 ? 117.885 119.616 106.902 1.00 32.17  ? 134 THR D O   1 
ATOM   1008  C  CB  . THR A 1 187 ? 119.407 117.256 107.882 1.00 25.02  ? 134 THR D CB  1 
ATOM   1009  O  OG1 . THR A 1 187 ? 119.918 115.923 107.920 1.00 33.95  ? 134 THR D OG1 1 
ATOM   1010  C  CG2 . THR A 1 187 ? 119.329 117.793 109.288 1.00 25.36  ? 134 THR D CG2 1 
ATOM   1011  N  N   . VAL A 1 188 ? 116.263 118.665 108.138 1.00 30.31  ? 135 VAL D N   1 
ATOM   1012  C  CA  . VAL A 1 188 ? 115.466 119.872 108.294 1.00 28.31  ? 135 VAL D CA  1 
ATOM   1013  C  C   . VAL A 1 188 ? 115.478 120.272 109.758 1.00 30.15  ? 135 VAL D C   1 
ATOM   1014  O  O   . VAL A 1 188 ? 115.303 119.426 110.639 1.00 31.65  ? 135 VAL D O   1 
ATOM   1015  C  CB  . VAL A 1 188 ? 114.025 119.663 107.801 1.00 25.27  ? 135 VAL D CB  1 
ATOM   1016  C  CG1 . VAL A 1 188 ? 113.260 120.964 107.851 1.00 25.56  ? 135 VAL D CG1 1 
ATOM   1017  C  CG2 . VAL A 1 188 ? 114.028 119.084 106.404 1.00 21.41  ? 135 VAL D CG2 1 
ATOM   1018  N  N   . ARG A 1 189 ? 115.722 121.550 110.013 1.00 28.20  ? 136 ARG D N   1 
ATOM   1019  C  CA  . ARG A 1 189 ? 115.558 122.150 111.330 1.00 28.74  ? 136 ARG D CA  1 
ATOM   1020  C  C   . ARG A 1 189 ? 114.310 123.014 111.266 1.00 30.79  ? 136 ARG D C   1 
ATOM   1021  O  O   . ARG A 1 189 ? 114.269 123.994 110.519 1.00 36.17  ? 136 ARG D O   1 
ATOM   1022  C  CB  . ARG A 1 189 ? 116.785 122.964 111.716 1.00 28.98  ? 136 ARG D CB  1 
ATOM   1023  C  CG  . ARG A 1 189 ? 118.042 122.141 111.803 1.00 37.67  ? 136 ARG D CG  1 
ATOM   1024  C  CD  . ARG A 1 189 ? 119.252 122.988 112.129 1.00 45.10  ? 136 ARG D CD  1 
ATOM   1025  N  NE  . ARG A 1 189 ? 119.035 123.865 113.272 1.00 48.73  ? 136 ARG D NE  1 
ATOM   1026  C  CZ  . ARG A 1 189 ? 119.079 125.187 113.214 1.00 45.72  ? 136 ARG D CZ  1 
ATOM   1027  N  NH1 . ARG A 1 189 ? 119.343 125.820 112.086 1.00 41.24  ? 136 ARG D NH1 1 
ATOM   1028  N  NH2 . ARG A 1 189 ? 118.866 125.892 114.320 1.00 45.02  ? 136 ARG D NH2 1 
ATOM   1029  N  N   . ALA A 1 190 ? 113.295 122.649 112.036 1.00 27.89  ? 137 ALA D N   1 
ATOM   1030  C  CA  . ALA A 1 190 ? 111.982 123.258 111.927 1.00 26.49  ? 137 ALA D CA  1 
ATOM   1031  C  C   . ALA A 1 190 ? 111.593 123.927 113.235 1.00 32.14  ? 137 ALA D C   1 
ATOM   1032  O  O   . ALA A 1 190 ? 111.951 123.460 114.317 1.00 37.08  ? 137 ALA D O   1 
ATOM   1033  C  CB  . ALA A 1 190 ? 110.936 122.217 111.545 1.00 28.49  ? 137 ALA D CB  1 
ATOM   1034  N  N   . GLU A 1 191 ? 110.840 125.021 113.122 1.00 32.28  ? 138 GLU D N   1 
ATOM   1035  C  CA  . GLU A 1 191 ? 110.342 125.736 114.290 1.00 35.23  ? 138 GLU D CA  1 
ATOM   1036  C  C   . GLU A 1 191 ? 109.195 124.975 114.935 1.00 39.48  ? 138 GLU D C   1 
ATOM   1037  O  O   . GLU A 1 191 ? 108.241 124.584 114.258 1.00 39.74  ? 138 GLU D O   1 
ATOM   1038  C  CB  . GLU A 1 191 ? 109.858 127.130 113.907 1.00 36.09  ? 138 GLU D CB  1 
ATOM   1039  C  CG  . GLU A 1 191 ? 110.736 127.869 112.940 1.00 43.12  ? 138 GLU D CG  1 
ATOM   1040  C  CD  . GLU A 1 191 ? 110.226 129.265 112.658 1.00 61.11  ? 138 GLU D CD  1 
ATOM   1041  O  OE1 . GLU A 1 191 ? 109.314 129.718 113.381 1.00 69.39  ? 138 GLU D OE1 1 
ATOM   1042  O  OE2 . GLU A 1 191 ? 110.729 129.908 111.713 1.00 63.63  ? 138 GLU D OE2 1 
ATOM   1043  N  N   . CYS A 1 192 ? 109.275 124.794 116.252 1.00 38.95  ? 139 CYS D N   1 
ATOM   1044  C  CA  . CYS A 1 192 ? 108.207 124.190 117.044 1.00 41.16  ? 139 CYS D CA  1 
ATOM   1045  C  C   . CYS A 1 192 ? 107.883 125.151 118.178 1.00 49.49  ? 139 CYS D C   1 
ATOM   1046  O  O   . CYS A 1 192 ? 108.532 125.119 119.231 1.00 56.59  ? 139 CYS D O   1 
ATOM   1047  C  CB  . CYS A 1 192 ? 108.610 122.815 117.577 1.00 40.92  ? 139 CYS D CB  1 
ATOM   1048  S  SG  . CYS A 1 192 ? 107.284 121.936 118.445 1.00 72.50  ? 139 CYS D SG  1 
ATOM   1049  N  N   . PRO A 1 193 ? 106.913 126.044 117.989 1.00 48.36  ? 140 PRO D N   1 
ATOM   1050  C  CA  . PRO A 1 193 ? 106.515 126.931 119.087 1.00 47.01  ? 140 PRO D CA  1 
ATOM   1051  C  C   . PRO A 1 193 ? 106.015 126.125 120.275 1.00 48.77  ? 140 PRO D C   1 
ATOM   1052  O  O   . PRO A 1 193 ? 105.321 125.120 120.118 1.00 50.61  ? 140 PRO D O   1 
ATOM   1053  C  CB  . PRO A 1 193 ? 105.395 127.775 118.473 1.00 44.20  ? 140 PRO D CB  1 
ATOM   1054  C  CG  . PRO A 1 193 ? 105.598 127.678 117.017 1.00 48.13  ? 140 PRO D CG  1 
ATOM   1055  C  CD  . PRO A 1 193 ? 106.143 126.312 116.767 1.00 46.31  ? 140 PRO D CD  1 
ATOM   1056  N  N   . MET A 1 194 ? 106.371 126.574 121.471 1.00 45.55  ? 141 MET D N   1 
ATOM   1057  C  CA  . MET A 1 194 ? 106.082 125.829 122.685 1.00 47.42  ? 141 MET D CA  1 
ATOM   1058  C  C   . MET A 1 194 ? 105.462 126.739 123.728 1.00 50.05  ? 141 MET D C   1 
ATOM   1059  O  O   . MET A 1 194 ? 105.949 127.848 123.962 1.00 56.52  ? 141 MET D O   1 
ATOM   1060  C  CB  . MET A 1 194 ? 107.350 125.189 123.244 1.00 46.81  ? 141 MET D CB  1 
ATOM   1061  C  CG  . MET A 1 194 ? 107.873 124.063 122.405 1.00 44.79  ? 141 MET D CG  1 
ATOM   1062  S  SD  . MET A 1 194 ? 109.432 123.423 123.003 1.00 57.46  ? 141 MET D SD  1 
ATOM   1063  C  CE  . MET A 1 194 ? 110.018 122.655 121.507 1.00 52.39  ? 141 MET D CE  1 
ATOM   1064  N  N   . HIS A 1 195 ? 104.394 126.263 124.351 1.00 46.70  ? 142 HIS D N   1 
ATOM   1065  C  CA  . HIS A 1 195 ? 103.810 126.889 125.525 1.00 46.85  ? 142 HIS D CA  1 
ATOM   1066  C  C   . HIS A 1 195 ? 104.110 125.989 126.711 1.00 48.41  ? 142 HIS D C   1 
ATOM   1067  O  O   . HIS A 1 195 ? 103.663 124.839 126.747 1.00 54.14  ? 142 HIS D O   1 
ATOM   1068  C  CB  . HIS A 1 195 ? 102.309 127.089 125.346 1.00 52.04  ? 142 HIS D CB  1 
ATOM   1069  C  CG  . HIS A 1 195 ? 101.946 127.814 124.091 1.00 58.42  ? 142 HIS D CG  1 
ATOM   1070  N  ND1 . HIS A 1 195 ? 101.844 129.186 124.028 1.00 60.69  ? 142 HIS D ND1 1 
ATOM   1071  C  CD2 . HIS A 1 195 ? 101.671 127.359 122.846 1.00 56.45  ? 142 HIS D CD2 1 
ATOM   1072  C  CE1 . HIS A 1 195 ? 101.518 129.545 122.800 1.00 62.34  ? 142 HIS D CE1 1 
ATOM   1073  N  NE2 . HIS A 1 195 ? 101.406 128.455 122.063 1.00 55.92  ? 142 HIS D NE2 1 
ATOM   1074  N  N   . LEU A 1 196 ? 104.877 126.504 127.670 1.00 45.66  ? 143 LEU D N   1 
ATOM   1075  C  CA  . LEU A 1 196 ? 105.430 125.686 128.740 1.00 40.88  ? 143 LEU D CA  1 
ATOM   1076  C  C   . LEU A 1 196 ? 104.780 125.958 130.088 1.00 42.43  ? 143 LEU D C   1 
ATOM   1077  O  O   . LEU A 1 196 ? 105.390 125.687 131.124 1.00 43.80  ? 143 LEU D O   1 
ATOM   1078  C  CB  . LEU A 1 196 ? 106.937 125.901 128.833 1.00 36.78  ? 143 LEU D CB  1 
ATOM   1079  C  CG  . LEU A 1 196 ? 107.709 125.718 127.531 1.00 35.05  ? 143 LEU D CG  1 
ATOM   1080  C  CD1 . LEU A 1 196 ? 109.149 126.107 127.718 1.00 34.18  ? 143 LEU D CD1 1 
ATOM   1081  C  CD2 . LEU A 1 196 ? 107.611 124.295 127.058 1.00 38.21  ? 143 LEU D CD2 1 
ATOM   1082  N  N   . GLU A 1 197 ? 103.551 126.472 130.102 1.00 42.03  ? 144 GLU D N   1 
ATOM   1083  C  CA  . GLU A 1 197 ? 102.886 126.731 131.372 1.00 42.20  ? 144 GLU D CA  1 
ATOM   1084  C  C   . GLU A 1 197 ? 102.640 125.457 132.164 1.00 47.81  ? 144 GLU D C   1 
ATOM   1085  O  O   . GLU A 1 197 ? 102.459 125.528 133.382 1.00 53.17  ? 144 GLU D O   1 
ATOM   1086  C  CB  . GLU A 1 197 ? 101.561 127.454 131.145 1.00 42.92  ? 144 GLU D CB  1 
ATOM   1087  C  CG  . GLU A 1 197 ? 101.681 128.786 130.431 1.00 49.34  ? 144 GLU D CG  1 
ATOM   1088  C  CD  . GLU A 1 197 ? 101.430 128.675 128.943 1.00 58.96  ? 144 GLU D CD  1 
ATOM   1089  O  OE1 . GLU A 1 197 ? 100.975 127.602 128.496 1.00 61.69  ? 144 GLU D OE1 1 
ATOM   1090  O  OE2 . GLU A 1 197 ? 101.679 129.660 128.220 1.00 58.06  ? 144 GLU D OE2 1 
ATOM   1091  N  N   . ASP A 1 198 ? 102.626 124.297 131.511 1.00 45.86  ? 145 ASP D N   1 
ATOM   1092  C  CA  . ASP A 1 198 ? 102.394 123.030 132.187 1.00 43.29  ? 145 ASP D CA  1 
ATOM   1093  C  C   . ASP A 1 198 ? 103.676 122.239 132.391 1.00 42.34  ? 145 ASP D C   1 
ATOM   1094  O  O   . ASP A 1 198 ? 103.618 121.041 132.674 1.00 46.98  ? 145 ASP D O   1 
ATOM   1095  C  CB  . ASP A 1 198 ? 101.376 122.198 131.412 1.00 48.55  ? 145 ASP D CB  1 
ATOM   1096  C  CG  . ASP A 1 198 ? 99.999  122.812 131.426 1.00 59.52  ? 145 ASP D CG  1 
ATOM   1097  O  OD1 . ASP A 1 198 ? 99.842  123.895 132.022 1.00 59.03  ? 145 ASP D OD1 1 
ATOM   1098  O  OD2 . ASP A 1 198 ? 99.070  122.221 130.842 1.00 66.84  ? 145 ASP D OD2 1 
ATOM   1099  N  N   . PHE A 1 199 ? 104.822 122.885 132.251 1.00 39.21  ? 146 PHE D N   1 
ATOM   1100  C  CA  . PHE A 1 199 ? 106.097 122.211 132.417 1.00 37.20  ? 146 PHE D CA  1 
ATOM   1101  C  C   . PHE A 1 199 ? 106.194 121.632 133.826 1.00 40.85  ? 146 PHE D C   1 
ATOM   1102  O  O   . PHE A 1 199 ? 105.763 122.275 134.787 1.00 46.45  ? 146 PHE D O   1 
ATOM   1103  C  CB  . PHE A 1 199 ? 107.225 123.209 132.160 1.00 34.11  ? 146 PHE D CB  1 
ATOM   1104  C  CG  . PHE A 1 199 ? 108.596 122.650 132.345 1.00 36.25  ? 146 PHE D CG  1 
ATOM   1105  C  CD1 . PHE A 1 199 ? 109.251 122.046 131.298 1.00 37.20  ? 146 PHE D CD1 1 
ATOM   1106  C  CD2 . PHE A 1 199 ? 109.242 122.752 133.558 1.00 38.47  ? 146 PHE D CD2 1 
ATOM   1107  C  CE1 . PHE A 1 199 ? 110.511 121.535 131.463 1.00 35.86  ? 146 PHE D CE1 1 
ATOM   1108  C  CE2 . PHE A 1 199 ? 110.500 122.242 133.725 1.00 38.01  ? 146 PHE D CE2 1 
ATOM   1109  C  CZ  . PHE A 1 199 ? 111.136 121.635 132.675 1.00 36.91  ? 146 PHE D CZ  1 
ATOM   1110  N  N   . PRO A 1 200 ? 106.740 120.423 133.994 1.00 37.52  ? 147 PRO D N   1 
ATOM   1111  C  CA  . PRO A 1 200 ? 107.279 119.489 133.006 1.00 36.25  ? 147 PRO D CA  1 
ATOM   1112  C  C   . PRO A 1 200 ? 106.266 118.457 132.541 1.00 38.16  ? 147 PRO D C   1 
ATOM   1113  O  O   . PRO A 1 200 ? 106.636 117.422 132.013 1.00 42.90  ? 147 PRO D O   1 
ATOM   1114  C  CB  . PRO A 1 200 ? 108.421 118.834 133.775 1.00 35.12  ? 147 PRO D CB  1 
ATOM   1115  C  CG  . PRO A 1 200 ? 107.874 118.725 135.154 1.00 34.76  ? 147 PRO D CG  1 
ATOM   1116  C  CD  . PRO A 1 200 ? 106.999 119.942 135.359 1.00 37.04  ? 147 PRO D CD  1 
ATOM   1117  N  N   . MET A 1 201 ? 104.975 118.698 132.744 1.00 38.78  ? 148 MET D N   1 
ATOM   1118  C  CA  . MET A 1 201 ? 103.924 117.809 132.268 1.00 38.01  ? 148 MET D CA  1 
ATOM   1119  C  C   . MET A 1 201 ? 103.317 118.298 130.961 1.00 41.67  ? 148 MET D C   1 
ATOM   1120  O  O   . MET A 1 201 ? 102.126 118.093 130.712 1.00 43.59  ? 148 MET D O   1 
ATOM   1121  C  CB  . MET A 1 201 ? 102.845 117.658 133.337 1.00 38.55  ? 148 MET D CB  1 
ATOM   1122  C  CG  . MET A 1 201 ? 103.264 116.781 134.491 1.00 42.20  ? 148 MET D CG  1 
ATOM   1123  S  SD  . MET A 1 201 ? 102.373 117.109 136.017 1.00 62.92  ? 148 MET D SD  1 
ATOM   1124  C  CE  . MET A 1 201 ? 102.957 118.756 136.392 1.00 52.34  ? 148 MET D CE  1 
ATOM   1125  N  N   . ASP A 1 202 ? 104.117 118.946 130.125 1.00 41.90  ? 149 ASP D N   1 
ATOM   1126  C  CA  . ASP A 1 202 ? 103.635 119.570 128.905 1.00 40.04  ? 149 ASP D CA  1 
ATOM   1127  C  C   . ASP A 1 202 ? 103.763 118.627 127.716 1.00 38.12  ? 149 ASP D C   1 
ATOM   1128  O  O   . ASP A 1 202 ? 104.616 117.738 127.691 1.00 41.16  ? 149 ASP D O   1 
ATOM   1129  C  CB  . ASP A 1 202 ? 104.411 120.855 128.636 1.00 39.11  ? 149 ASP D CB  1 
ATOM   1130  C  CG  . ASP A 1 202 ? 105.898 120.629 128.599 1.00 39.77  ? 149 ASP D CG  1 
ATOM   1131  O  OD1 . ASP A 1 202 ? 106.350 119.604 129.138 1.00 40.49  ? 149 ASP D OD1 1 
ATOM   1132  O  OD2 . ASP A 1 202 ? 106.618 121.468 128.031 1.00 41.77  ? 149 ASP D OD2 1 
ATOM   1133  N  N   . ALA A 1 203 ? 102.895 118.829 126.730 1.00 36.81  ? 150 ALA D N   1 
ATOM   1134  C  CA  . ALA A 1 203 ? 102.911 118.070 125.491 1.00 34.97  ? 150 ALA D CA  1 
ATOM   1135  C  C   . ALA A 1 203 ? 102.817 119.034 124.320 1.00 38.46  ? 150 ALA D C   1 
ATOM   1136  O  O   . ALA A 1 203 ? 102.171 120.079 124.411 1.00 40.40  ? 150 ALA D O   1 
ATOM   1137  C  CB  . ALA A 1 203 ? 101.761 117.061 125.429 1.00 33.91  ? 150 ALA D CB  1 
ATOM   1138  N  N   . HIS A 1 204 ? 103.458 118.674 123.214 1.00 37.57  ? 151 HIS D N   1 
ATOM   1139  C  CA  . HIS A 1 204 ? 103.535 119.556 122.059 1.00 38.09  ? 151 HIS D CA  1 
ATOM   1140  C  C   . HIS A 1 204 ? 103.205 118.790 120.789 1.00 39.56  ? 151 HIS D C   1 
ATOM   1141  O  O   . HIS A 1 204 ? 103.272 117.562 120.743 1.00 41.65  ? 151 HIS D O   1 
ATOM   1142  C  CB  . HIS A 1 204 ? 104.921 120.193 121.937 1.00 36.95  ? 151 HIS D CB  1 
ATOM   1143  C  CG  . HIS A 1 204 ? 105.479 120.659 123.242 1.00 38.36  ? 151 HIS D CG  1 
ATOM   1144  N  ND1 . HIS A 1 204 ? 104.947 121.720 123.939 1.00 41.65  ? 151 HIS D ND1 1 
ATOM   1145  C  CD2 . HIS A 1 204 ? 106.514 120.203 123.983 1.00 40.50  ? 151 HIS D CD2 1 
ATOM   1146  C  CE1 . HIS A 1 204 ? 105.631 121.899 125.053 1.00 42.30  ? 151 HIS D CE1 1 
ATOM   1147  N  NE2 . HIS A 1 204 ? 106.588 120.991 125.103 1.00 44.38  ? 151 HIS D NE2 1 
ATOM   1148  N  N   . ALA A 1 205 ? 102.834 119.537 119.754 1.00 36.59  ? 152 ALA D N   1 
ATOM   1149  C  CA  . ALA A 1 205 ? 102.601 118.992 118.418 1.00 37.07  ? 152 ALA D CA  1 
ATOM   1150  C  C   . ALA A 1 205 ? 103.493 119.772 117.463 1.00 41.34  ? 152 ALA D C   1 
ATOM   1151  O  O   . ALA A 1 205 ? 103.078 120.788 116.903 1.00 42.96  ? 152 ALA D O   1 
ATOM   1152  C  CB  . ALA A 1 205 ? 101.136 119.079 118.025 1.00 33.72  ? 152 ALA D CB  1 
ATOM   1153  N  N   . CYS A 1 206 ? 104.714 119.291 117.282 1.00 38.70  ? 153 CYS D N   1 
ATOM   1154  C  CA  . CYS A 1 206 ? 105.680 119.987 116.441 1.00 36.40  ? 153 CYS D CA  1 
ATOM   1155  C  C   . CYS A 1 206 ? 105.312 119.824 114.975 1.00 38.25  ? 153 CYS D C   1 
ATOM   1156  O  O   . CYS A 1 206 ? 105.145 118.690 114.512 1.00 40.66  ? 153 CYS D O   1 
ATOM   1157  C  CB  . CYS A 1 206 ? 107.081 119.459 116.705 1.00 37.79  ? 153 CYS D CB  1 
ATOM   1158  S  SG  . CYS A 1 206 ? 107.751 119.961 118.301 1.00 72.69  ? 153 CYS D SG  1 
ATOM   1159  N  N   . PRO A 1 207 ? 105.154 120.904 114.220 1.00 35.09  ? 154 PRO D N   1 
ATOM   1160  C  CA  . PRO A 1 207 ? 104.677 120.790 112.844 1.00 33.34  ? 154 PRO D CA  1 
ATOM   1161  C  C   . PRO A 1 207 ? 105.795 120.764 111.810 1.00 32.50  ? 154 PRO D C   1 
ATOM   1162  O  O   . PRO A 1 207 ? 106.934 121.159 112.057 1.00 34.53  ? 154 PRO D O   1 
ATOM   1163  C  CB  . PRO A 1 207 ? 103.824 122.053 112.687 1.00 32.72  ? 154 PRO D CB  1 
ATOM   1164  C  CG  . PRO A 1 207 ? 104.511 123.047 113.538 1.00 33.10  ? 154 PRO D CG  1 
ATOM   1165  C  CD  . PRO A 1 207 ? 105.167 122.303 114.675 1.00 34.04  ? 154 PRO D CD  1 
ATOM   1166  N  N   . LEU A 1 208 ? 105.431 120.276 110.632 1.00 28.00  ? 155 LEU D N   1 
ATOM   1167  C  CA  . LEU A 1 208 ? 106.297 120.272 109.459 1.00 28.18  ? 155 LEU D CA  1 
ATOM   1168  C  C   . LEU A 1 208 ? 105.402 120.572 108.267 1.00 31.14  ? 155 LEU D C   1 
ATOM   1169  O  O   . LEU A 1 208 ? 104.595 119.727 107.874 1.00 36.83  ? 155 LEU D O   1 
ATOM   1170  C  CB  . LEU A 1 208 ? 107.011 118.933 109.298 1.00 29.33  ? 155 LEU D CB  1 
ATOM   1171  C  CG  . LEU A 1 208 ? 107.922 118.726 108.091 1.00 24.64  ? 155 LEU D CG  1 
ATOM   1172  C  CD1 . LEU A 1 208 ? 109.217 119.468 108.274 1.00 24.88  ? 155 LEU D CD1 1 
ATOM   1173  C  CD2 . LEU A 1 208 ? 108.182 117.254 107.873 1.00 25.37  ? 155 LEU D CD2 1 
ATOM   1174  N  N   . LYS A 1 209 ? 105.516 121.778 107.721 1.00 27.66  ? 156 LYS D N   1 
ATOM   1175  C  CA  . LYS A 1 209 ? 104.661 122.245 106.640 1.00 27.01  ? 156 LYS D CA  1 
ATOM   1176  C  C   . LYS A 1 209 ? 105.513 122.492 105.409 1.00 26.52  ? 156 LYS D C   1 
ATOM   1177  O  O   . LYS A 1 209 ? 106.550 123.151 105.495 1.00 28.00  ? 156 LYS D O   1 
ATOM   1178  C  CB  . LYS A 1 209 ? 103.928 123.526 107.041 1.00 27.80  ? 156 LYS D CB  1 
ATOM   1179  C  CG  . LYS A 1 209 ? 103.436 123.519 108.470 1.00 31.68  ? 156 LYS D CG  1 
ATOM   1180  C  CD  . LYS A 1 209 ? 102.908 124.871 108.899 1.00 36.44  ? 156 LYS D CD  1 
ATOM   1181  C  CE  . LYS A 1 209 ? 101.447 125.034 108.537 1.00 38.65  ? 156 LYS D CE  1 
ATOM   1182  N  NZ  . LYS A 1 209 ? 100.606 123.987 109.173 1.00 35.93  ? 156 LYS D NZ  1 
ATOM   1183  N  N   . PHE A 1 210 ? 105.090 121.956 104.269 1.00 26.83  ? 157 PHE D N   1 
ATOM   1184  C  CA  . PHE A 1 210 ? 105.840 122.164 103.040 1.00 25.99  ? 157 PHE D CA  1 
ATOM   1185  C  C   . PHE A 1 210 ? 104.892 122.378 101.871 1.00 28.18  ? 157 PHE D C   1 
ATOM   1186  O  O   . PHE A 1 210 ? 103.713 122.028 101.917 1.00 30.24  ? 157 PHE D O   1 
ATOM   1187  C  CB  . PHE A 1 210 ? 106.808 121.006 102.744 1.00 25.00  ? 157 PHE D CB  1 
ATOM   1188  C  CG  . PHE A 1 210 ? 106.146 119.676 102.550 1.00 27.81  ? 157 PHE D CG  1 
ATOM   1189  C  CD1 . PHE A 1 210 ? 105.916 118.847 103.622 1.00 26.84  ? 157 PHE D CD1 1 
ATOM   1190  C  CD2 . PHE A 1 210 ? 105.779 119.245 101.290 1.00 27.91  ? 157 PHE D CD2 1 
ATOM   1191  C  CE1 . PHE A 1 210 ? 105.323 117.629 103.445 1.00 27.18  ? 157 PHE D CE1 1 
ATOM   1192  C  CE2 . PHE A 1 210 ? 105.184 118.026 101.111 1.00 25.84  ? 157 PHE D CE2 1 
ATOM   1193  C  CZ  . PHE A 1 210 ? 104.955 117.218 102.188 1.00 26.59  ? 157 PHE D CZ  1 
ATOM   1194  N  N   . GLY A 1 211 ? 105.431 122.977 100.820 1.00 25.63  ? 158 GLY D N   1 
ATOM   1195  C  CA  . GLY A 1 211 ? 104.627 123.290 99.655  1.00 24.45  ? 158 GLY D CA  1 
ATOM   1196  C  C   . GLY A 1 211 ? 105.470 123.971 98.606  1.00 27.37  ? 158 GLY D C   1 
ATOM   1197  O  O   . GLY A 1 211 ? 106.677 124.159 98.770  1.00 30.92  ? 158 GLY D O   1 
ATOM   1198  N  N   . SER A 1 212 ? 104.816 124.328 97.508  1.00 28.76  ? 159 SER D N   1 
ATOM   1199  C  CA  . SER A 1 212 ? 105.509 124.984 96.408  1.00 27.93  ? 159 SER D CA  1 
ATOM   1200  C  C   . SER A 1 212 ? 105.828 126.428 96.762  1.00 28.04  ? 159 SER D C   1 
ATOM   1201  O  O   . SER A 1 212 ? 105.041 127.110 97.419  1.00 31.93  ? 159 SER D O   1 
ATOM   1202  C  CB  . SER A 1 212 ? 104.660 124.930 95.147  1.00 27.91  ? 159 SER D CB  1 
ATOM   1203  O  OG  . SER A 1 212 ? 105.419 125.305 94.022  1.00 30.28  ? 159 SER D OG  1 
ATOM   1204  N  N   . TYR A 1 213 ? 106.992 126.899 96.323  1.00 25.41  ? 160 TYR D N   1 
ATOM   1205  C  CA  . TYR A 1 213 ? 107.393 128.262 96.642  1.00 25.81  ? 160 TYR D CA  1 
ATOM   1206  C  C   . TYR A 1 213 ? 106.913 129.286 95.628  1.00 29.18  ? 160 TYR D C   1 
ATOM   1207  O  O   . TYR A 1 213 ? 106.632 130.426 96.005  1.00 31.76  ? 160 TYR D O   1 
ATOM   1208  C  CB  . TYR A 1 213 ? 108.913 128.376 96.760  1.00 24.18  ? 160 TYR D CB  1 
ATOM   1209  C  CG  . TYR A 1 213 ? 109.329 129.738 97.253  1.00 24.22  ? 160 TYR D CG  1 
ATOM   1210  C  CD1 . TYR A 1 213 ? 109.212 130.073 98.589  1.00 25.30  ? 160 TYR D CD1 1 
ATOM   1211  C  CD2 . TYR A 1 213 ? 109.805 130.699 96.383  1.00 23.59  ? 160 TYR D CD2 1 
ATOM   1212  C  CE1 . TYR A 1 213 ? 109.570 131.314 99.044  1.00 22.84  ? 160 TYR D CE1 1 
ATOM   1213  C  CE2 . TYR A 1 213 ? 110.164 131.943 96.832  1.00 25.13  ? 160 TYR D CE2 1 
ATOM   1214  C  CZ  . TYR A 1 213 ? 110.043 132.242 98.163  1.00 24.79  ? 160 TYR D CZ  1 
ATOM   1215  O  OH  . TYR A 1 213 ? 110.393 133.481 98.623  1.00 30.99  ? 160 TYR D OH  1 
ATOM   1216  N  N   . ALA A 1 214 ? 106.823 128.923 94.354  1.00 29.36  ? 161 ALA D N   1 
ATOM   1217  C  CA  . ALA A 1 214 ? 106.484 129.881 93.318  1.00 29.48  ? 161 ALA D CA  1 
ATOM   1218  C  C   . ALA A 1 214 ? 105.217 129.553 92.549  1.00 37.88  ? 161 ALA D C   1 
ATOM   1219  O  O   . ALA A 1 214 ? 104.704 130.432 91.851  1.00 45.07  ? 161 ALA D O   1 
ATOM   1220  C  CB  . ALA A 1 214 ? 107.639 130.018 92.319  1.00 29.83  ? 161 ALA D CB  1 
ATOM   1221  N  N   . TYR A 1 215 ? 104.701 128.333 92.643  1.00 39.36  ? 162 TYR D N   1 
ATOM   1222  C  CA  . TYR A 1 215 ? 103.546 127.912 91.863  1.00 37.23  ? 162 TYR D CA  1 
ATOM   1223  C  C   . TYR A 1 215 ? 102.306 127.925 92.745  1.00 38.85  ? 162 TYR D C   1 
ATOM   1224  O  O   . TYR A 1 215 ? 102.232 127.182 93.726  1.00 41.42  ? 162 TYR D O   1 
ATOM   1225  C  CB  . TYR A 1 215 ? 103.773 126.523 91.272  1.00 34.33  ? 162 TYR D CB  1 
ATOM   1226  C  CG  . TYR A 1 215 ? 104.822 126.496 90.194  1.00 33.31  ? 162 TYR D CG  1 
ATOM   1227  C  CD1 . TYR A 1 215 ? 104.486 126.730 88.876  1.00 36.28  ? 162 TYR D CD1 1 
ATOM   1228  C  CD2 . TYR A 1 215 ? 106.149 126.253 90.496  1.00 31.15  ? 162 TYR D CD2 1 
ATOM   1229  C  CE1 . TYR A 1 215 ? 105.434 126.714 87.889  1.00 38.77  ? 162 TYR D CE1 1 
ATOM   1230  C  CE2 . TYR A 1 215 ? 107.106 126.237 89.513  1.00 33.12  ? 162 TYR D CE2 1 
ATOM   1231  C  CZ  . TYR A 1 215 ? 106.742 126.470 88.211  1.00 38.87  ? 162 TYR D CZ  1 
ATOM   1232  O  OH  . TYR A 1 215 ? 107.691 126.453 87.221  1.00 41.27  ? 162 TYR D OH  1 
ATOM   1233  N  N   . THR A 1 216 ? 101.333 128.757 92.385  1.00 42.78  ? 163 THR D N   1 
ATOM   1234  C  CA  . THR A 1 216 ? 100.108 128.865 93.159  1.00 41.66  ? 163 THR D CA  1 
ATOM   1235  C  C   . THR A 1 216 ? 99.244  127.626 92.939  1.00 43.11  ? 163 THR D C   1 
ATOM   1236  O  O   . THR A 1 216 ? 99.571  126.738 92.152  1.00 44.68  ? 163 THR D O   1 
ATOM   1237  C  CB  . THR A 1 216 ? 99.355  130.138 92.789  1.00 41.01  ? 163 THR D CB  1 
ATOM   1238  O  OG1 . THR A 1 216 ? 98.965  130.084 91.413  1.00 46.55  ? 163 THR D OG1 1 
ATOM   1239  C  CG2 . THR A 1 216 ? 100.240 131.339 92.994  1.00 41.19  ? 163 THR D CG2 1 
ATOM   1240  N  N   . ARG A 1 217 ? 98.113  127.569 93.643  1.00 42.48  ? 164 ARG D N   1 
ATOM   1241  C  CA  . ARG A 1 217 ? 97.290  126.366 93.614  1.00 41.22  ? 164 ARG D CA  1 
ATOM   1242  C  C   . ARG A 1 217 ? 96.709  126.095 92.238  1.00 43.63  ? 164 ARG D C   1 
ATOM   1243  O  O   . ARG A 1 217 ? 96.318  124.959 91.958  1.00 44.69  ? 164 ARG D O   1 
ATOM   1244  C  CB  . ARG A 1 217 ? 96.159  126.473 94.632  1.00 41.37  ? 164 ARG D CB  1 
ATOM   1245  C  CG  . ARG A 1 217 ? 95.099  127.483 94.256  1.00 52.19  ? 164 ARG D CG  1 
ATOM   1246  C  CD  . ARG A 1 217 ? 94.133  127.712 95.399  1.00 57.50  ? 164 ARG D CD  1 
ATOM   1247  N  NE  . ARG A 1 217 ? 93.527  126.471 95.858  1.00 62.94  ? 164 ARG D NE  1 
ATOM   1248  C  CZ  . ARG A 1 217 ? 92.337  126.033 95.474  1.00 69.32  ? 164 ARG D CZ  1 
ATOM   1249  N  NH1 . ARG A 1 217 ? 91.589  126.720 94.627  1.00 69.00  ? 164 ARG D NH1 1 
ATOM   1250  N  NH2 . ARG A 1 217 ? 91.887  124.877 95.952  1.00 69.20  ? 164 ARG D NH2 1 
ATOM   1251  N  N   . ALA A 1 218 ? 96.646  127.102 91.373  1.00 42.95  ? 165 ALA D N   1 
ATOM   1252  C  CA  . ALA A 1 218 ? 96.118  126.913 90.033  1.00 42.18  ? 165 ALA D CA  1 
ATOM   1253  C  C   . ALA A 1 218 ? 97.132  126.290 89.091  1.00 43.17  ? 165 ALA D C   1 
ATOM   1254  O  O   . ALA A 1 218 ? 96.792  126.010 87.940  1.00 42.63  ? 165 ALA D O   1 
ATOM   1255  C  CB  . ALA A 1 218 ? 95.639  128.246 89.460  1.00 42.64  ? 165 ALA D CB  1 
ATOM   1256  N  N   . GLU A 1 219 ? 98.362  126.080 89.552  1.00 44.79  ? 166 GLU D N   1 
ATOM   1257  C  CA  . GLU A 1 219 ? 99.430  125.513 88.744  1.00 41.51  ? 166 GLU D CA  1 
ATOM   1258  C  C   . GLU A 1 219 ? 99.939  124.188 89.284  1.00 41.52  ? 166 GLU D C   1 
ATOM   1259  O  O   . GLU A 1 219 ? 99.981  123.202 88.543  1.00 45.22  ? 166 GLU D O   1 
ATOM   1260  C  CB  . GLU A 1 219 ? 100.583 126.518 88.644  1.00 42.07  ? 166 GLU D CB  1 
ATOM   1261  C  CG  . GLU A 1 219 ? 100.226 127.776 87.884  1.00 47.70  ? 166 GLU D CG  1 
ATOM   1262  C  CD  . GLU A 1 219 ? 101.338 128.800 87.886  1.00 60.30  ? 166 GLU D CD  1 
ATOM   1263  O  OE1 . GLU A 1 219 ? 101.595 129.400 88.950  1.00 56.15  ? 166 GLU D OE1 1 
ATOM   1264  O  OE2 . GLU A 1 219 ? 101.959 128.999 86.822  1.00 65.83  ? 166 GLU D OE2 1 
ATOM   1265  N  N   . VAL A 1 220 ? 100.325 124.130 90.556  1.00 40.75  ? 167 VAL D N   1 
ATOM   1266  C  CA  . VAL A 1 220 ? 100.868 122.920 91.162  1.00 39.40  ? 167 VAL D CA  1 
ATOM   1267  C  C   . VAL A 1 220 ? 100.080 122.606 92.423  1.00 41.84  ? 167 VAL D C   1 
ATOM   1268  O  O   . VAL A 1 220 ? 99.939  123.462 93.301  1.00 42.99  ? 167 VAL D O   1 
ATOM   1269  C  CB  . VAL A 1 220 ? 102.365 123.067 91.488  1.00 34.91  ? 167 VAL D CB  1 
ATOM   1270  C  CG1 . VAL A 1 220 ? 102.835 121.924 92.353  1.00 31.99  ? 167 VAL D CG1 1 
ATOM   1271  C  CG2 . VAL A 1 220 ? 103.168 123.108 90.217  1.00 38.30  ? 167 VAL D CG2 1 
ATOM   1272  N  N   . VAL A 1 221 ? 99.584  121.375 92.516  1.00 44.34  ? 168 VAL D N   1 
ATOM   1273  C  CA  . VAL A 1 221 ? 98.932  120.879 93.717  1.00 39.37  ? 168 VAL D CA  1 
ATOM   1274  C  C   . VAL A 1 221 ? 99.717  119.679 94.223  1.00 37.51  ? 168 VAL D C   1 
ATOM   1275  O  O   . VAL A 1 221 ? 100.423 119.005 93.472  1.00 40.01  ? 168 VAL D O   1 
ATOM   1276  C  CB  . VAL A 1 221 ? 97.461  120.499 93.474  1.00 38.26  ? 168 VAL D CB  1 
ATOM   1277  C  CG1 . VAL A 1 221 ? 96.693  121.693 92.972  1.00 39.15  ? 168 VAL D CG1 1 
ATOM   1278  C  CG2 . VAL A 1 221 ? 97.368  119.361 92.490  1.00 41.61  ? 168 VAL D CG2 1 
ATOM   1279  N  N   . TYR A 1 222 ? 99.590  119.420 95.516  1.00 35.00  ? 169 TYR D N   1 
ATOM   1280  C  CA  . TYR A 1 222 ? 100.284 118.320 96.160  1.00 32.10  ? 169 TYR D CA  1 
ATOM   1281  C  C   . TYR A 1 222 ? 99.275  117.330 96.719  1.00 36.38  ? 169 TYR D C   1 
ATOM   1282  O  O   . TYR A 1 222 ? 98.177  117.703 97.135  1.00 41.94  ? 169 TYR D O   1 
ATOM   1283  C  CB  . TYR A 1 222 ? 101.199 118.820 97.272  1.00 30.06  ? 169 TYR D CB  1 
ATOM   1284  C  CG  . TYR A 1 222 ? 102.435 119.526 96.783  1.00 31.19  ? 169 TYR D CG  1 
ATOM   1285  C  CD1 . TYR A 1 222 ? 102.385 120.845 96.376  1.00 30.31  ? 169 TYR D CD1 1 
ATOM   1286  C  CD2 . TYR A 1 222 ? 103.656 118.877 96.744  1.00 32.38  ? 169 TYR D CD2 1 
ATOM   1287  C  CE1 . TYR A 1 222 ? 103.511 121.492 95.933  1.00 29.09  ? 169 TYR D CE1 1 
ATOM   1288  C  CE2 . TYR A 1 222 ? 104.784 119.516 96.308  1.00 29.08  ? 169 TYR D CE2 1 
ATOM   1289  C  CZ  . TYR A 1 222 ? 104.708 120.822 95.902  1.00 30.96  ? 169 TYR D CZ  1 
ATOM   1290  O  OH  . TYR A 1 222 ? 105.837 121.463 95.465  1.00 33.47  ? 169 TYR D OH  1 
ATOM   1291  N  N   . GLU A 1 223 ? 99.657  116.060 96.714  1.00 37.44  ? 170 GLU D N   1 
ATOM   1292  C  CA  . GLU A 1 223 ? 98.842  114.986 97.253  1.00 40.09  ? 170 GLU D CA  1 
ATOM   1293  C  C   . GLU A 1 223 ? 99.758  113.997 97.951  1.00 42.58  ? 170 GLU D C   1 
ATOM   1294  O  O   . GLU A 1 223 ? 100.967 113.980 97.721  1.00 48.01  ? 170 GLU D O   1 
ATOM   1295  C  CB  . GLU A 1 223 ? 98.040  114.285 96.154  1.00 43.92  ? 170 GLU D CB  1 
ATOM   1296  C  CG  . GLU A 1 223 ? 97.017  115.171 95.484  1.00 56.33  ? 170 GLU D CG  1 
ATOM   1297  C  CD  . GLU A 1 223 ? 96.542  114.617 94.165  1.00 77.22  ? 170 GLU D CD  1 
ATOM   1298  O  OE1 . GLU A 1 223 ? 96.899  113.466 93.837  1.00 78.36  ? 170 GLU D OE1 1 
ATOM   1299  O  OE2 . GLU A 1 223 ? 95.814  115.336 93.451  1.00 85.48  ? 170 GLU D OE2 1 
ATOM   1300  N  N   . TRP A 1 224 ? 99.178  113.176 98.815  1.00 38.12  ? 171 TRP D N   1 
ATOM   1301  C  CA  . TRP A 1 224 ? 99.926  112.115 99.468  1.00 38.84  ? 171 TRP D CA  1 
ATOM   1302  C  C   . TRP A 1 224 ? 99.891  110.860 98.607  1.00 45.54  ? 171 TRP D C   1 
ATOM   1303  O  O   . TRP A 1 224 ? 98.884  110.569 97.959  1.00 52.61  ? 171 TRP D O   1 
ATOM   1304  C  CB  . TRP A 1 224 ? 99.362  111.833 100.859 1.00 39.09  ? 171 TRP D CB  1 
ATOM   1305  C  CG  . TRP A 1 224 ? 99.480  112.996 101.796 1.00 37.39  ? 171 TRP D CG  1 
ATOM   1306  C  CD1 . TRP A 1 224 ? 98.485  113.838 102.175 1.00 39.51  ? 171 TRP D CD1 1 
ATOM   1307  C  CD2 . TRP A 1 224 ? 100.663 113.447 102.471 1.00 37.36  ? 171 TRP D CD2 1 
ATOM   1308  N  NE1 . TRP A 1 224 ? 98.966  114.782 103.041 1.00 39.85  ? 171 TRP D NE1 1 
ATOM   1309  C  CE2 . TRP A 1 224 ? 100.302 114.566 103.238 1.00 37.67  ? 171 TRP D CE2 1 
ATOM   1310  C  CE3 . TRP A 1 224 ? 101.989 113.014 102.498 1.00 36.06  ? 171 TRP D CE3 1 
ATOM   1311  C  CZ2 . TRP A 1 224 ? 101.215 115.255 104.029 1.00 34.39  ? 171 TRP D CZ2 1 
ATOM   1312  C  CZ3 . TRP A 1 224 ? 102.894 113.701 103.278 1.00 33.57  ? 171 TRP D CZ3 1 
ATOM   1313  C  CH2 . TRP A 1 224 ? 102.504 114.807 104.035 1.00 33.21  ? 171 TRP D CH2 1 
ATOM   1314  N  N   . THR A 1 225 ? 101.009 110.131 98.589  1.00 45.06  ? 172 THR D N   1 
ATOM   1315  C  CA  . THR A 1 225 ? 101.145 108.993 97.685  1.00 48.06  ? 172 THR D CA  1 
ATOM   1316  C  C   . THR A 1 225 ? 100.099 107.927 97.975  1.00 54.08  ? 172 THR D C   1 
ATOM   1317  O  O   . THR A 1 225 ? 99.428  107.428 97.065  1.00 57.39  ? 172 THR D O   1 
ATOM   1318  C  CB  . THR A 1 225 ? 102.546 108.399 97.803  1.00 50.13  ? 172 THR D CB  1 
ATOM   1319  O  OG1 . THR A 1 225 ? 103.495 109.453 97.989  1.00 50.66  ? 172 THR D OG1 1 
ATOM   1320  C  CG2 . THR A 1 225 ? 102.902 107.643 96.548  1.00 50.94  ? 172 THR D CG2 1 
ATOM   1321  N  N   . ARG A 1 226 ? 99.943  107.577 99.240  1.00 55.84  ? 173 ARG D N   1 
ATOM   1322  C  CA  . ARG A 1 226 ? 98.997  106.587 99.729  1.00 55.95  ? 173 ARG D CA  1 
ATOM   1323  C  C   . ARG A 1 226 ? 98.034  107.295 100.675 1.00 57.69  ? 173 ARG D C   1 
ATOM   1324  O  O   . ARG A 1 226 ? 97.931  108.521 100.665 1.00 57.78  ? 173 ARG D O   1 
ATOM   1325  C  CB  . ARG A 1 226 ? 99.734  105.419 100.386 1.00 58.41  ? 173 ARG D CB  1 
ATOM   1326  C  CG  . ARG A 1 226 ? 100.807 105.834 101.369 1.00 60.36  ? 173 ARG D CG  1 
ATOM   1327  C  CD  . ARG A 1 226 ? 101.690 104.660 101.745 1.00 62.43  ? 173 ARG D CD  1 
ATOM   1328  N  NE  . ARG A 1 226 ? 102.518 104.228 100.626 1.00 63.87  ? 173 ARG D NE  1 
ATOM   1329  C  CZ  . ARG A 1 226 ? 103.775 104.601 100.439 1.00 62.50  ? 173 ARG D CZ  1 
ATOM   1330  N  NH1 . ARG A 1 226 ? 104.392 105.401 101.292 1.00 53.79  ? 173 ARG D NH1 1 
ATOM   1331  N  NH2 . ARG A 1 226 ? 104.431 104.158 99.372  1.00 65.35  ? 173 ARG D NH2 1 
ATOM   1332  N  N   . GLU A 1 227 ? 97.292  106.520 101.455 1.00 63.36  ? 174 GLU D N   1 
ATOM   1333  C  CA  . GLU A 1 227 ? 96.405  107.117 102.441 1.00 64.23  ? 174 GLU D CA  1 
ATOM   1334  C  C   . GLU A 1 227 ? 97.193  108.090 103.315 1.00 58.98  ? 174 GLU D C   1 
ATOM   1335  O  O   . GLU A 1 227 ? 98.346  107.810 103.662 1.00 60.10  ? 174 GLU D O   1 
ATOM   1336  C  CB  . GLU A 1 227 ? 95.758  106.040 103.315 1.00 68.65  ? 174 GLU D CB  1 
ATOM   1337  C  CG  . GLU A 1 227 ? 95.090  104.920 102.550 1.00 78.64  ? 174 GLU D CG  1 
ATOM   1338  C  CD  . GLU A 1 227 ? 96.026  103.767 102.263 1.00 86.95  ? 174 GLU D CD  1 
ATOM   1339  O  OE1 . GLU A 1 227 ? 97.204  103.844 102.666 1.00 87.03  ? 174 GLU D OE1 1 
ATOM   1340  O  OE2 . GLU A 1 227 ? 95.584  102.782 101.637 1.00 92.58  ? 174 GLU D OE2 1 
ATOM   1341  N  N   . PRO A 1 228 ? 96.620  109.243 103.668 1.00 55.16  ? 175 PRO D N   1 
ATOM   1342  C  CA  . PRO A 1 228 ? 97.422  110.274 104.347 1.00 51.02  ? 175 PRO D CA  1 
ATOM   1343  C  C   . PRO A 1 228 ? 98.071  109.797 105.629 1.00 52.76  ? 175 PRO D C   1 
ATOM   1344  O  O   . PRO A 1 228 ? 99.200  110.198 105.928 1.00 51.74  ? 175 PRO D O   1 
ATOM   1345  C  CB  . PRO A 1 228 ? 96.399  111.385 104.610 1.00 48.47  ? 175 PRO D CB  1 
ATOM   1346  C  CG  . PRO A 1 228 ? 95.349  111.173 103.591 1.00 52.06  ? 175 PRO D CG  1 
ATOM   1347  C  CD  . PRO A 1 228 ? 95.246  109.698 103.411 1.00 56.11  ? 175 PRO D CD  1 
ATOM   1348  N  N   . ALA A 1 229 ? 97.396  108.937 106.390 1.00 53.81  ? 176 ALA D N   1 
ATOM   1349  C  CA  . ALA A 1 229 ? 97.947  108.496 107.666 1.00 53.73  ? 176 ALA D CA  1 
ATOM   1350  C  C   . ALA A 1 229 ? 99.219  107.684 107.482 1.00 55.97  ? 176 ALA D C   1 
ATOM   1351  O  O   . ALA A 1 229 ? 100.099 107.708 108.348 1.00 56.91  ? 176 ALA D O   1 
ATOM   1352  C  CB  . ALA A 1 229 ? 96.906  107.684 108.434 1.00 54.34  ? 176 ALA D CB  1 
ATOM   1353  N  N   . ARG A 1 230 ? 99.341  106.967 106.368 1.00 58.61  ? 177 ARG D N   1 
ATOM   1354  C  CA  . ARG A 1 230 ? 100.466 106.076 106.129 1.00 55.88  ? 177 ARG D CA  1 
ATOM   1355  C  C   . ARG A 1 230 ? 101.471 106.635 105.134 1.00 52.95  ? 177 ARG D C   1 
ATOM   1356  O  O   . ARG A 1 230 ? 102.348 105.898 104.679 1.00 55.93  ? 177 ARG D O   1 
ATOM   1357  C  CB  . ARG A 1 230 ? 99.963  104.716 105.649 1.00 62.85  ? 177 ARG D CB  1 
ATOM   1358  C  CG  . ARG A 1 230 ? 98.871  104.133 106.526 1.00 69.38  ? 177 ARG D CG  1 
ATOM   1359  C  CD  . ARG A 1 230 ? 98.606  102.673 106.210 1.00 82.25  ? 177 ARG D CD  1 
ATOM   1360  N  NE  . ARG A 1 230 ? 98.367  102.442 104.790 1.00 93.72  ? 177 ARG D NE  1 
ATOM   1361  C  CZ  . ARG A 1 230 ? 99.241  101.883 103.965 1.00 96.58  ? 177 ARG D CZ  1 
ATOM   1362  N  NH1 . ARG A 1 230 ? 100.429 101.481 104.385 1.00 92.22  ? 177 ARG D NH1 1 
ATOM   1363  N  NH2 . ARG A 1 230 ? 98.913  101.720 102.686 1.00 94.50  ? 177 ARG D NH2 1 
ATOM   1364  N  N   . SER A 1 231 ? 101.356 107.908 104.769 1.00 51.82  ? 178 SER D N   1 
ATOM   1365  C  CA  . SER A 1 231 ? 102.300 108.525 103.851 1.00 44.58  ? 178 SER D CA  1 
ATOM   1366  C  C   . SER A 1 231 ? 103.521 109.105 104.546 1.00 37.67  ? 178 SER D C   1 
ATOM   1367  O  O   . SER A 1 231 ? 104.501 109.421 103.870 1.00 39.73  ? 178 SER D O   1 
ATOM   1368  C  CB  . SER A 1 231 ? 101.616 109.624 103.041 1.00 44.84  ? 178 SER D CB  1 
ATOM   1369  O  OG  . SER A 1 231 ? 100.681 109.080 102.132 1.00 47.97  ? 178 SER D OG  1 
ATOM   1370  N  N   . VAL A 1 232 ? 103.490 109.260 105.863 1.00 37.28  ? 179 VAL D N   1 
ATOM   1371  C  CA  . VAL A 1 232 ? 104.654 109.667 106.639 1.00 36.96  ? 179 VAL D CA  1 
ATOM   1372  C  C   . VAL A 1 232 ? 105.017 108.507 107.548 1.00 39.92  ? 179 VAL D C   1 
ATOM   1373  O  O   . VAL A 1 232 ? 104.237 108.141 108.434 1.00 43.54  ? 179 VAL D O   1 
ATOM   1374  C  CB  . VAL A 1 232 ? 104.387 110.939 107.452 1.00 37.92  ? 179 VAL D CB  1 
ATOM   1375  C  CG1 . VAL A 1 232 ? 105.558 111.229 108.356 1.00 34.74  ? 179 VAL D CG1 1 
ATOM   1376  C  CG2 . VAL A 1 232 ? 104.141 112.108 106.530 1.00 34.73  ? 179 VAL D CG2 1 
ATOM   1377  N  N   . VAL A 1 233 ? 106.191 107.922 107.329 1.00 36.20  ? 180 VAL D N   1 
ATOM   1378  C  CA  . VAL A 1 233 ? 106.585 106.692 108.006 1.00 33.40  ? 180 VAL D CA  1 
ATOM   1379  C  C   . VAL A 1 233 ? 107.865 106.940 108.781 1.00 35.07  ? 180 VAL D C   1 
ATOM   1380  O  O   . VAL A 1 233 ? 108.862 107.380 108.206 1.00 37.12  ? 180 VAL D O   1 
ATOM   1381  C  CB  . VAL A 1 233 ? 106.769 105.536 107.012 1.00 29.97  ? 180 VAL D CB  1 
ATOM   1382  C  CG1 . VAL A 1 233 ? 107.285 104.313 107.729 1.00 32.10  ? 180 VAL D CG1 1 
ATOM   1383  C  CG2 . VAL A 1 233 ? 105.461 105.238 106.330 1.00 36.29  ? 180 VAL D CG2 1 
ATOM   1384  N  N   . VAL A 1 234 ? 107.847 106.630 110.073 1.00 36.97  ? 181 VAL D N   1 
ATOM   1385  C  CA  . VAL A 1 234 ? 108.987 106.841 110.957 1.00 36.61  ? 181 VAL D CA  1 
ATOM   1386  C  C   . VAL A 1 234 ? 109.662 105.504 111.221 1.00 44.36  ? 181 VAL D C   1 
ATOM   1387  O  O   . VAL A 1 234 ? 108.999 104.527 111.585 1.00 50.70  ? 181 VAL D O   1 
ATOM   1388  C  CB  . VAL A 1 234 ? 108.551 107.504 112.272 1.00 32.79  ? 181 VAL D CB  1 
ATOM   1389  C  CG1 . VAL A 1 234 ? 109.756 107.873 113.095 1.00 32.06  ? 181 VAL D CG1 1 
ATOM   1390  C  CG2 . VAL A 1 234 ? 107.719 108.722 111.977 1.00 34.95  ? 181 VAL D CG2 1 
ATOM   1391  N  N   . ALA A 1 235 ? 110.979 105.462 111.044 1.00 46.06  ? 182 ALA D N   1 
ATOM   1392  C  CA  . ALA A 1 235 ? 111.731 104.231 111.234 1.00 47.29  ? 182 ALA D CA  1 
ATOM   1393  C  C   . ALA A 1 235 ? 111.689 103.783 112.688 1.00 61.06  ? 182 ALA D C   1 
ATOM   1394  O  O   . ALA A 1 235 ? 111.604 104.595 113.612 1.00 62.23  ? 182 ALA D O   1 
ATOM   1395  C  CB  . ALA A 1 235 ? 113.179 104.419 110.795 1.00 41.79  ? 182 ALA D CB  1 
ATOM   1396  N  N   . GLU A 1 236 ? 111.753 102.464 112.881 1.00 68.08  ? 183 GLU D N   1 
ATOM   1397  C  CA  . GLU A 1 236 ? 111.643 101.897 114.221 1.00 72.20  ? 183 GLU D CA  1 
ATOM   1398  C  C   . GLU A 1 236 ? 112.814 102.308 115.103 1.00 70.96  ? 183 GLU D C   1 
ATOM   1399  O  O   . GLU A 1 236 ? 112.631 102.617 116.285 1.00 68.54  ? 183 GLU D O   1 
ATOM   1400  C  CB  . GLU A 1 236 ? 111.544 100.376 114.129 1.00 78.93  ? 183 GLU D CB  1 
ATOM   1401  C  CG  . GLU A 1 236 ? 110.348 99.892  113.336 1.00 87.08  ? 183 GLU D CG  1 
ATOM   1402  C  CD  . GLU A 1 236 ? 110.338 98.389  113.146 1.00 107.37 ? 183 GLU D CD  1 
ATOM   1403  O  OE1 . GLU A 1 236 ? 110.889 97.670  114.007 1.00 112.52 ? 183 GLU D OE1 1 
ATOM   1404  O  OE2 . GLU A 1 236 ? 109.781 97.924  112.128 1.00 111.44 ? 183 GLU D OE2 1 
ATOM   1405  N  N   . ASP A 1 237 ? 114.024 102.313 114.552 1.00 72.68  ? 184 ASP D N   1 
ATOM   1406  C  CA  . ASP A 1 237 ? 115.211 102.653 115.323 1.00 72.86  ? 184 ASP D CA  1 
ATOM   1407  C  C   . ASP A 1 237 ? 115.550 104.133 115.292 1.00 68.36  ? 184 ASP D C   1 
ATOM   1408  O  O   . ASP A 1 237 ? 116.369 104.582 116.098 1.00 65.52  ? 184 ASP D O   1 
ATOM   1409  C  CB  . ASP A 1 237 ? 116.411 101.861 114.808 1.00 78.57  ? 184 ASP D CB  1 
ATOM   1410  C  CG  . ASP A 1 237 ? 116.092 100.403 114.603 1.00 88.00  ? 184 ASP D CG  1 
ATOM   1411  O  OD1 . ASP A 1 237 ? 115.321 99.846  115.411 1.00 91.47  ? 184 ASP D OD1 1 
ATOM   1412  O  OD2 . ASP A 1 237 ? 116.603 99.816  113.627 1.00 91.79  ? 184 ASP D OD2 1 
ATOM   1413  N  N   . GLY A 1 238 ? 114.947 104.897 114.391 1.00 66.64  ? 185 GLY D N   1 
ATOM   1414  C  CA  . GLY A 1 238 ? 115.317 106.283 114.208 1.00 55.99  ? 185 GLY D CA  1 
ATOM   1415  C  C   . GLY A 1 238 ? 114.695 107.205 115.227 1.00 55.86  ? 185 GLY D C   1 
ATOM   1416  O  O   . GLY A 1 238 ? 113.712 107.890 114.938 1.00 53.94  ? 185 GLY D O   1 
ATOM   1417  N  N   . SER A 1 239 ? 115.250 107.218 116.433 1.00 55.17  ? 186 SER D N   1 
ATOM   1418  C  CA  . SER A 1 239 ? 114.759 108.081 117.501 1.00 46.42  ? 186 SER D CA  1 
ATOM   1419  C  C   . SER A 1 239 ? 115.956 108.607 118.271 1.00 40.93  ? 186 SER D C   1 
ATOM   1420  O  O   . SER A 1 239 ? 116.571 107.867 119.040 1.00 47.75  ? 186 SER D O   1 
ATOM   1421  C  CB  . SER A 1 239 ? 113.808 107.334 118.428 1.00 49.17  ? 186 SER D CB  1 
ATOM   1422  O  OG  . SER A 1 239 ? 113.505 108.118 119.565 1.00 49.04  ? 186 SER D OG  1 
ATOM   1423  N  N   . ARG A 1 240 ? 116.286 109.878 118.065 1.00 33.84  ? 187 ARG D N   1 
ATOM   1424  C  CA  . ARG A 1 240 ? 117.355 110.531 118.800 1.00 33.42  ? 187 ARG D CA  1 
ATOM   1425  C  C   . ARG A 1 240 ? 116.827 111.457 119.886 1.00 37.28  ? 187 ARG D C   1 
ATOM   1426  O  O   . ARG A 1 240 ? 117.538 112.371 120.312 1.00 38.51  ? 187 ARG D O   1 
ATOM   1427  C  CB  . ARG A 1 240 ? 118.259 111.295 117.837 1.00 34.25  ? 187 ARG D CB  1 
ATOM   1428  C  CG  . ARG A 1 240 ? 118.763 110.447 116.689 1.00 35.71  ? 187 ARG D CG  1 
ATOM   1429  C  CD  . ARG A 1 240 ? 119.687 111.232 115.798 1.00 35.81  ? 187 ARG D CD  1 
ATOM   1430  N  NE  . ARG A 1 240 ? 120.048 110.475 114.608 1.00 42.88  ? 187 ARG D NE  1 
ATOM   1431  C  CZ  . ARG A 1 240 ? 120.796 110.947 113.622 1.00 42.43  ? 187 ARG D CZ  1 
ATOM   1432  N  NH1 . ARG A 1 240 ? 121.293 112.171 113.658 1.00 39.66  ? 187 ARG D NH1 1 
ATOM   1433  N  NH2 . ARG A 1 240 ? 121.055 110.170 112.576 1.00 38.92  ? 187 ARG D NH2 1 
ATOM   1434  N  N   . LEU A 1 241 ? 115.593 111.244 120.332 1.00 39.09  ? 188 LEU D N   1 
ATOM   1435  C  CA  . LEU A 1 241 ? 115.018 112.027 121.415 1.00 38.01  ? 188 LEU D CA  1 
ATOM   1436  C  C   . LEU A 1 241 ? 115.529 111.532 122.756 1.00 42.91  ? 188 LEU D C   1 
ATOM   1437  O  O   . LEU A 1 241 ? 115.495 110.332 123.039 1.00 45.45  ? 188 LEU D O   1 
ATOM   1438  C  CB  . LEU A 1 241 ? 113.497 111.936 121.391 1.00 35.60  ? 188 LEU D CB  1 
ATOM   1439  C  CG  . LEU A 1 241 ? 112.764 112.536 120.205 1.00 29.89  ? 188 LEU D CG  1 
ATOM   1440  C  CD1 . LEU A 1 241 ? 111.328 112.104 120.251 1.00 32.10  ? 188 LEU D CD1 1 
ATOM   1441  C  CD2 . LEU A 1 241 ? 112.858 114.028 120.257 1.00 31.57  ? 188 LEU D CD2 1 
ATOM   1442  N  N   . ASN A 1 242 ? 115.988 112.460 123.589 1.00 44.44  ? 189 ASN D N   1 
ATOM   1443  C  CA  . ASN A 1 242 ? 116.383 112.152 124.955 1.00 44.06  ? 189 ASN D CA  1 
ATOM   1444  C  C   . ASN A 1 242 ? 115.295 112.513 125.953 1.00 45.51  ? 189 ASN D C   1 
ATOM   1445  O  O   . ASN A 1 242 ? 114.946 111.707 126.817 1.00 43.88  ? 189 ASN D O   1 
ATOM   1446  C  CB  . ASN A 1 242 ? 117.670 112.898 125.316 1.00 44.29  ? 189 ASN D CB  1 
ATOM   1447  C  CG  . ASN A 1 242 ? 118.681 112.889 124.199 1.00 50.16  ? 189 ASN D CG  1 
ATOM   1448  O  OD1 . ASN A 1 242 ? 119.032 113.935 123.660 1.00 50.53  ? 189 ASN D OD1 1 
ATOM   1449  N  ND2 . ASN A 1 242 ? 119.165 111.706 123.850 1.00 53.71  ? 189 ASN D ND2 1 
ATOM   1450  N  N   . GLN A 1 243 ? 114.737 113.712 125.825 1.00 44.85  ? 190 GLN D N   1 
ATOM   1451  C  CA  . GLN A 1 243 ? 113.828 114.280 126.803 1.00 41.05  ? 190 GLN D CA  1 
ATOM   1452  C  C   . GLN A 1 243 ? 112.360 114.068 126.474 1.00 40.49  ? 190 GLN D C   1 
ATOM   1453  O  O   . GLN A 1 243 ? 111.514 114.333 127.329 1.00 41.32  ? 190 GLN D O   1 
ATOM   1454  C  CB  . GLN A 1 243 ? 114.099 115.778 126.928 1.00 43.44  ? 190 GLN D CB  1 
ATOM   1455  C  CG  . GLN A 1 243 ? 113.934 116.333 128.314 1.00 53.22  ? 190 GLN D CG  1 
ATOM   1456  C  CD  . GLN A 1 243 ? 114.472 117.738 128.418 1.00 62.82  ? 190 GLN D CD  1 
ATOM   1457  O  OE1 . GLN A 1 243 ? 114.106 118.495 129.320 1.00 64.60  ? 190 GLN D OE1 1 
ATOM   1458  N  NE2 . GLN A 1 243 ? 115.351 118.098 127.492 1.00 59.12  ? 190 GLN D NE2 1 
ATOM   1459  N  N   . TYR A 1 244 ? 112.033 113.582 125.282 1.00 42.91  ? 191 TYR D N   1 
ATOM   1460  C  CA  . TYR A 1 244 ? 110.653 113.492 124.833 1.00 36.31  ? 191 TYR D CA  1 
ATOM   1461  C  C   . TYR A 1 244 ? 110.342 112.088 124.349 1.00 36.69  ? 191 TYR D C   1 
ATOM   1462  O  O   . TYR A 1 244 ? 111.235 111.278 124.098 1.00 42.22  ? 191 TYR D O   1 
ATOM   1463  C  CB  . TYR A 1 244 ? 110.353 114.484 123.706 1.00 35.02  ? 191 TYR D CB  1 
ATOM   1464  C  CG  . TYR A 1 244 ? 110.365 115.926 124.126 1.00 35.12  ? 191 TYR D CG  1 
ATOM   1465  C  CD1 . TYR A 1 244 ? 109.232 116.519 124.650 1.00 34.16  ? 191 TYR D CD1 1 
ATOM   1466  C  CD2 . TYR A 1 244 ? 111.506 116.693 123.992 1.00 35.06  ? 191 TYR D CD2 1 
ATOM   1467  C  CE1 . TYR A 1 244 ? 109.234 117.826 125.033 1.00 36.33  ? 191 TYR D CE1 1 
ATOM   1468  C  CE2 . TYR A 1 244 ? 111.518 118.002 124.377 1.00 37.57  ? 191 TYR D CE2 1 
ATOM   1469  C  CZ  . TYR A 1 244 ? 110.378 118.564 124.896 1.00 40.64  ? 191 TYR D CZ  1 
ATOM   1470  O  OH  . TYR A 1 244 ? 110.381 119.879 125.276 1.00 48.75  ? 191 TYR D OH  1 
ATOM   1471  N  N   . ASP A 1 245 ? 109.051 111.815 124.221 1.00 36.42  ? 192 ASP D N   1 
ATOM   1472  C  CA  . ASP A 1 245 ? 108.552 110.542 123.733 1.00 38.61  ? 192 ASP D CA  1 
ATOM   1473  C  C   . ASP A 1 245 ? 107.583 110.818 122.596 1.00 41.32  ? 192 ASP D C   1 
ATOM   1474  O  O   . ASP A 1 245 ? 106.627 111.578 122.766 1.00 43.63  ? 192 ASP D O   1 
ATOM   1475  C  CB  . ASP A 1 245 ? 107.871 109.764 124.860 1.00 40.45  ? 192 ASP D CB  1 
ATOM   1476  C  CG  . ASP A 1 245 ? 107.870 108.273 124.622 1.00 55.94  ? 192 ASP D CG  1 
ATOM   1477  O  OD1 . ASP A 1 245 ? 107.496 107.842 123.512 1.00 63.50  ? 192 ASP D OD1 1 
ATOM   1478  O  OD2 . ASP A 1 245 ? 108.252 107.527 125.546 1.00 58.74  ? 192 ASP D OD2 1 
ATOM   1479  N  N   . LEU A 1 246 ? 107.832 110.213 121.440 1.00 39.83  ? 193 LEU D N   1 
ATOM   1480  C  CA  . LEU A 1 246 ? 107.018 110.446 120.255 1.00 39.37  ? 193 LEU D CA  1 
ATOM   1481  C  C   . LEU A 1 246 ? 105.803 109.528 120.286 1.00 43.91  ? 193 LEU D C   1 
ATOM   1482  O  O   . LEU A 1 246 ? 105.946 108.303 120.273 1.00 45.09  ? 193 LEU D O   1 
ATOM   1483  C  CB  . LEU A 1 246 ? 107.836 110.217 118.987 1.00 39.87  ? 193 LEU D CB  1 
ATOM   1484  C  CG  . LEU A 1 246 ? 107.101 110.404 117.663 1.00 39.16  ? 193 LEU D CG  1 
ATOM   1485  C  CD1 . LEU A 1 246 ? 106.597 111.810 117.547 1.00 35.33  ? 193 LEU D CD1 1 
ATOM   1486  C  CD2 . LEU A 1 246 ? 108.020 110.087 116.511 1.00 39.22  ? 193 LEU D CD2 1 
ATOM   1487  N  N   . LEU A 1 247 ? 104.614 110.120 120.334 1.00 42.05  ? 194 LEU D N   1 
ATOM   1488  C  CA  . LEU A 1 247 ? 103.372 109.371 120.455 1.00 39.05  ? 194 LEU D CA  1 
ATOM   1489  C  C   . LEU A 1 247 ? 102.699 109.094 119.119 1.00 41.38  ? 194 LEU D C   1 
ATOM   1490  O  O   . LEU A 1 247 ? 101.687 108.390 119.090 1.00 46.03  ? 194 LEU D O   1 
ATOM   1491  C  CB  . LEU A 1 247 ? 102.394 110.123 121.359 1.00 39.25  ? 194 LEU D CB  1 
ATOM   1492  C  CG  . LEU A 1 247 ? 102.862 110.441 122.775 1.00 39.25  ? 194 LEU D CG  1 
ATOM   1493  C  CD1 . LEU A 1 247 ? 101.803 111.249 123.489 1.00 38.35  ? 194 LEU D CD1 1 
ATOM   1494  C  CD2 . LEU A 1 247 ? 103.169 109.171 123.536 1.00 38.66  ? 194 LEU D CD2 1 
ATOM   1495  N  N   . GLY A 1 248 ? 103.222 109.629 118.023 1.00 41.25  ? 195 GLY D N   1 
ATOM   1496  C  CA  . GLY A 1 248 ? 102.614 109.437 116.723 1.00 40.14  ? 195 GLY D CA  1 
ATOM   1497  C  C   . GLY A 1 248 ? 102.574 110.719 115.923 1.00 42.37  ? 195 GLY D C   1 
ATOM   1498  O  O   . GLY A 1 248 ? 103.075 111.751 116.377 1.00 43.03  ? 195 GLY D O   1 
ATOM   1499  N  N   . GLN A 1 249 ? 101.988 110.673 114.729 1.00 41.01  ? 196 GLN D N   1 
ATOM   1500  C  CA  . GLN A 1 249 ? 101.913 111.846 113.875 1.00 36.99  ? 196 GLN D CA  1 
ATOM   1501  C  C   . GLN A 1 249 ? 100.568 111.898 113.171 1.00 39.43  ? 196 GLN D C   1 
ATOM   1502  O  O   . GLN A 1 249 ? 99.944  110.871 112.903 1.00 45.69  ? 196 GLN D O   1 
ATOM   1503  C  CB  . GLN A 1 249 ? 103.036 111.878 112.832 1.00 36.83  ? 196 GLN D CB  1 
ATOM   1504  C  CG  . GLN A 1 249 ? 103.150 110.640 111.980 1.00 40.11  ? 196 GLN D CG  1 
ATOM   1505  C  CD  . GLN A 1 249 ? 104.055 109.603 112.595 1.00 46.69  ? 196 GLN D CD  1 
ATOM   1506  O  OE1 . GLN A 1 249 ? 104.659 109.833 113.637 1.00 46.24  ? 196 GLN D OE1 1 
ATOM   1507  N  NE2 . GLN A 1 249 ? 104.151 108.450 111.953 1.00 47.77  ? 196 GLN D NE2 1 
ATOM   1508  N  N   . THR A 1 250 ? 100.144 113.118 112.870 1.00 38.23  ? 197 THR D N   1 
ATOM   1509  C  CA  . THR A 1 250 ? 98.896  113.400 112.180 1.00 38.64  ? 197 THR D CA  1 
ATOM   1510  C  C   . THR A 1 250 ? 99.205  114.117 110.877 1.00 41.47  ? 197 THR D C   1 
ATOM   1511  O  O   . THR A 1 250 ? 100.060 115.003 110.838 1.00 41.09  ? 197 THR D O   1 
ATOM   1512  C  CB  . THR A 1 250 ? 97.973  114.256 113.044 1.00 38.16  ? 197 THR D CB  1 
ATOM   1513  O  OG1 . THR A 1 250 ? 97.821  113.641 114.327 1.00 43.39  ? 197 THR D OG1 1 
ATOM   1514  C  CG2 . THR A 1 250 ? 96.613  114.389 112.402 1.00 39.37  ? 197 THR D CG2 1 
ATOM   1515  N  N   . VAL A 1 251 ? 98.510  113.737 109.811 1.00 42.58  ? 198 VAL D N   1 
ATOM   1516  C  CA  . VAL A 1 251 ? 98.828  114.180 108.460 1.00 38.24  ? 198 VAL D CA  1 
ATOM   1517  C  C   . VAL A 1 251 ? 97.634  114.928 107.890 1.00 41.96  ? 198 VAL D C   1 
ATOM   1518  O  O   . VAL A 1 251 ? 96.503  114.437 107.956 1.00 51.47  ? 198 VAL D O   1 
ATOM   1519  C  CB  . VAL A 1 251 ? 99.210  112.990 107.565 1.00 36.66  ? 198 VAL D CB  1 
ATOM   1520  C  CG1 . VAL A 1 251 ? 99.128  113.382 106.129 1.00 38.99  ? 198 VAL D CG1 1 
ATOM   1521  C  CG2 . VAL A 1 251 ? 100.604 112.526 107.893 1.00 35.11  ? 198 VAL D CG2 1 
ATOM   1522  N  N   . ASP A 1 252 ? 97.884  116.107 107.322 1.00 40.65  ? 199 ASP D N   1 
ATOM   1523  C  CA  . ASP A 1 252 ? 96.803  116.942 106.822 1.00 40.19  ? 199 ASP D CA  1 
ATOM   1524  C  C   . ASP A 1 252 ? 97.292  117.757 105.632 1.00 42.47  ? 199 ASP D C   1 
ATOM   1525  O  O   . ASP A 1 252 ? 98.484  117.799 105.328 1.00 42.73  ? 199 ASP D O   1 
ATOM   1526  C  CB  . ASP A 1 252 ? 96.275  117.856 107.924 1.00 45.36  ? 199 ASP D CB  1 
ATOM   1527  C  CG  . ASP A 1 252 ? 94.920  118.419 107.602 1.00 62.71  ? 199 ASP D CG  1 
ATOM   1528  O  OD1 . ASP A 1 252 ? 94.333  117.978 106.594 1.00 63.20  ? 199 ASP D OD1 1 
ATOM   1529  O  OD2 . ASP A 1 252 ? 94.442  119.301 108.348 1.00 72.45  ? 199 ASP D OD2 1 
ATOM   1530  N  N   . SER A 1 253 ? 96.348  118.404 104.951 1.00 46.58  ? 200 SER D N   1 
ATOM   1531  C  CA  . SER A 1 253 ? 96.670  119.322 103.869 1.00 42.80  ? 200 SER D CA  1 
ATOM   1532  C  C   . SER A 1 253 ? 95.644  120.444 103.846 1.00 45.93  ? 200 SER D C   1 
ATOM   1533  O  O   . SER A 1 253 ? 94.521  120.293 104.328 1.00 49.12  ? 200 SER D O   1 
ATOM   1534  C  CB  . SER A 1 253 ? 96.714  118.611 102.515 1.00 39.40  ? 200 SER D CB  1 
ATOM   1535  O  OG  . SER A 1 253 ? 95.466  118.024 102.206 1.00 46.09  ? 200 SER D OG  1 
ATOM   1536  N  N   . GLY A 1 254 ? 96.041  121.572 103.274 1.00 47.01  ? 201 GLY D N   1 
ATOM   1537  C  CA  . GLY A 1 254 ? 95.165  122.723 103.238 1.00 43.50  ? 201 GLY D CA  1 
ATOM   1538  C  C   . GLY A 1 254 ? 95.695  123.793 102.314 1.00 41.96  ? 201 GLY D C   1 
ATOM   1539  O  O   . GLY A 1 254 ? 96.620  123.567 101.537 1.00 43.07  ? 201 GLY D O   1 
ATOM   1540  N  N   . ILE A 1 255 ? 95.101  124.977 102.421 1.00 43.67  ? 202 ILE D N   1 
ATOM   1541  C  CA  . ILE A 1 255 ? 95.417  126.108 101.557 1.00 42.18  ? 202 ILE D CA  1 
ATOM   1542  C  C   . ILE A 1 255 ? 95.906  127.260 102.418 1.00 44.04  ? 202 ILE D C   1 
ATOM   1543  O  O   . ILE A 1 255 ? 95.267  127.610 103.415 1.00 50.29  ? 202 ILE D O   1 
ATOM   1544  C  CB  . ILE A 1 255 ? 94.198  126.545 100.728 1.00 41.08  ? 202 ILE D CB  1 
ATOM   1545  C  CG1 . ILE A 1 255 ? 93.651  125.377 99.915  1.00 42.86  ? 202 ILE D CG1 1 
ATOM   1546  C  CG2 . ILE A 1 255 ? 94.562  127.697 99.823  1.00 41.94  ? 202 ILE D CG2 1 
ATOM   1547  C  CD1 . ILE A 1 255 ? 94.577  124.908 98.838  1.00 42.70  ? 202 ILE D CD1 1 
ATOM   1548  N  N   . VAL A 1 256 ? 97.032  127.848 102.035 1.00 41.00  ? 203 VAL D N   1 
ATOM   1549  C  CA  . VAL A 1 256 ? 97.518  129.066 102.661 1.00 42.64  ? 203 VAL D CA  1 
ATOM   1550  C  C   . VAL A 1 256 ? 97.442  130.179 101.627 1.00 47.25  ? 203 VAL D C   1 
ATOM   1551  O  O   . VAL A 1 256 ? 97.441  129.939 100.419 1.00 52.02  ? 203 VAL D O   1 
ATOM   1552  C  CB  . VAL A 1 256 ? 98.949  128.915 103.214 1.00 40.30  ? 203 VAL D CB  1 
ATOM   1553  C  CG1 . VAL A 1 256 ? 99.978  129.345 102.187 1.00 38.93  ? 203 VAL D CG1 1 
ATOM   1554  C  CG2 . VAL A 1 256 ? 99.109  129.704 104.494 1.00 48.34  ? 203 VAL D CG2 1 
ATOM   1555  N  N   . GLN A 1 257 ? 97.347  131.410 102.107 1.00 47.64  ? 204 GLN D N   1 
ATOM   1556  C  CA  . GLN A 1 257 ? 97.176  132.553 101.224 1.00 47.61  ? 204 GLN D CA  1 
ATOM   1557  C  C   . GLN A 1 257 ? 98.112  133.673 101.641 1.00 51.03  ? 204 GLN D C   1 
ATOM   1558  O  O   . GLN A 1 257 ? 98.152  134.045 102.817 1.00 55.38  ? 204 GLN D O   1 
ATOM   1559  C  CB  . GLN A 1 257 ? 95.732  133.038 101.239 1.00 46.97  ? 204 GLN D CB  1 
ATOM   1560  C  CG  . GLN A 1 257 ? 95.517  134.267 100.401 1.00 58.17  ? 204 GLN D CG  1 
ATOM   1561  C  CD  . GLN A 1 257 ? 94.061  134.598 100.233 1.00 76.05  ? 204 GLN D CD  1 
ATOM   1562  O  OE1 . GLN A 1 257 ? 93.189  133.832 100.641 1.00 81.03  ? 204 GLN D OE1 1 
ATOM   1563  N  NE2 . GLN A 1 257 ? 93.782  135.747 99.631  1.00 83.20  ? 204 GLN D NE2 1 
ATOM   1564  N  N   . SER A 1 258 ? 98.854  134.216 100.678 1.00 47.02  ? 205 SER D N   1 
ATOM   1565  C  CA  . SER A 1 258 ? 99.813  135.277 100.941 1.00 45.30  ? 205 SER D CA  1 
ATOM   1566  C  C   . SER A 1 258 ? 99.702  136.331 99.850  1.00 47.09  ? 205 SER D C   1 
ATOM   1567  O  O   . SER A 1 258 ? 98.864  136.240 98.947  1.00 50.96  ? 205 SER D O   1 
ATOM   1568  C  CB  . SER A 1 258 ? 101.239 134.729 101.031 1.00 44.34  ? 205 SER D CB  1 
ATOM   1569  O  OG  . SER A 1 258 ? 101.596 134.038 99.851  1.00 44.93  ? 205 SER D OG  1 
ATOM   1570  N  N   . SER A 1 259 ? 100.583 137.331 99.931  1.00 48.18  ? 206 SER D N   1 
ATOM   1571  C  CA  . SER A 1 259 ? 100.531 138.462 99.011  1.00 49.25  ? 206 SER D CA  1 
ATOM   1572  C  C   . SER A 1 259 ? 100.684 138.033 97.561  1.00 48.14  ? 206 SER D C   1 
ATOM   1573  O  O   . SER A 1 259 ? 100.223 138.736 96.655  1.00 47.76  ? 206 SER D O   1 
ATOM   1574  C  CB  . SER A 1 259 ? 101.617 139.476 99.367  1.00 48.34  ? 206 SER D CB  1 
ATOM   1575  O  OG  . SER A 1 259 ? 102.896 138.875 99.345  1.00 47.28  ? 206 SER D OG  1 
ATOM   1576  N  N   . THR A 1 260 ? 101.326 136.895 97.316  1.00 45.01  ? 207 THR D N   1 
ATOM   1577  C  CA  . THR A 1 260 ? 101.531 136.421 95.958  1.00 42.11  ? 207 THR D CA  1 
ATOM   1578  C  C   . THR A 1 260 ? 100.442 135.471 95.474  1.00 44.32  ? 207 THR D C   1 
ATOM   1579  O  O   . THR A 1 260 ? 100.423 135.147 94.284  1.00 47.16  ? 207 THR D O   1 
ATOM   1580  C  CB  . THR A 1 260 ? 102.894 135.736 95.841  1.00 41.22  ? 207 THR D CB  1 
ATOM   1581  O  OG1 . THR A 1 260 ? 102.931 134.597 96.704  1.00 48.21  ? 207 THR D OG1 1 
ATOM   1582  C  CG2 . THR A 1 260 ? 103.994 136.689 96.247  1.00 36.53  ? 207 THR D CG2 1 
ATOM   1583  N  N   . GLY A 1 261 ? 99.540  135.024 96.339  1.00 43.89  ? 208 GLY D N   1 
ATOM   1584  C  CA  . GLY A 1 261 ? 98.470  134.161 95.890  1.00 41.14  ? 208 GLY D CA  1 
ATOM   1585  C  C   . GLY A 1 261 ? 98.223  133.039 96.870  1.00 42.93  ? 208 GLY D C   1 
ATOM   1586  O  O   . GLY A 1 261 ? 98.659  133.090 98.016  1.00 47.58  ? 208 GLY D O   1 
ATOM   1587  N  N   . GLU A 1 262 ? 97.519  132.013 96.401  1.00 42.30  ? 209 GLU D N   1 
ATOM   1588  C  CA  . GLU A 1 262 ? 97.106  130.885 97.226  1.00 42.03  ? 209 GLU D CA  1 
ATOM   1589  C  C   . GLU A 1 262 ? 97.919  129.651 96.872  1.00 42.30  ? 209 GLU D C   1 
ATOM   1590  O  O   . GLU A 1 262 ? 98.042  129.302 95.696  1.00 46.66  ? 209 GLU D O   1 
ATOM   1591  C  CB  . GLU A 1 262 ? 95.621  130.589 97.040  1.00 46.00  ? 209 GLU D CB  1 
ATOM   1592  C  CG  . GLU A 1 262 ? 94.711  131.733 97.404  1.00 60.82  ? 209 GLU D CG  1 
ATOM   1593  C  CD  . GLU A 1 262 ? 93.253  131.376 97.227  1.00 76.74  ? 209 GLU D CD  1 
ATOM   1594  O  OE1 . GLU A 1 262 ? 92.963  130.182 97.014  1.00 74.22  ? 209 GLU D OE1 1 
ATOM   1595  O  OE2 . GLU A 1 262 ? 92.400  132.288 97.295  1.00 83.89  ? 209 GLU D OE2 1 
ATOM   1596  N  N   . TYR A 1 263 ? 98.437  128.976 97.890  1.00 37.99  ? 210 TYR D N   1 
ATOM   1597  C  CA  . TYR A 1 263 ? 99.285  127.811 97.708  1.00 37.63  ? 210 TYR D CA  1 
ATOM   1598  C  C   . TYR A 1 263 ? 98.733  126.650 98.519  1.00 37.81  ? 210 TYR D C   1 
ATOM   1599  O  O   . TYR A 1 263 ? 97.966  126.836 99.465  1.00 42.85  ? 210 TYR D O   1 
ATOM   1600  C  CB  . TYR A 1 263 ? 100.733 128.103 98.120  1.00 38.62  ? 210 TYR D CB  1 
ATOM   1601  C  CG  . TYR A 1 263 ? 101.372 129.248 97.371  1.00 37.42  ? 210 TYR D CG  1 
ATOM   1602  C  CD1 . TYR A 1 263 ? 101.124 130.559 97.731  1.00 37.17  ? 210 TYR D CD1 1 
ATOM   1603  C  CD2 . TYR A 1 263 ? 102.225 129.015 96.309  1.00 36.91  ? 210 TYR D CD2 1 
ATOM   1604  C  CE1 . TYR A 1 263 ? 101.697 131.599 97.051  1.00 36.58  ? 210 TYR D CE1 1 
ATOM   1605  C  CE2 . TYR A 1 263 ? 102.807 130.054 95.626  1.00 37.25  ? 210 TYR D CE2 1 
ATOM   1606  C  CZ  . TYR A 1 263 ? 102.539 131.342 96.003  1.00 39.79  ? 210 TYR D CZ  1 
ATOM   1607  O  OH  . TYR A 1 263 ? 103.116 132.382 95.326  1.00 45.64  ? 210 TYR D OH  1 
ATOM   1608  N  N   . VAL A 1 264 ? 99.122  125.448 98.128  1.00 37.66  ? 211 VAL D N   1 
ATOM   1609  C  CA  . VAL A 1 264 ? 98.768  124.235 98.855  1.00 35.56  ? 211 VAL D CA  1 
ATOM   1610  C  C   . VAL A 1 264 ? 99.862  123.945 99.869  1.00 33.96  ? 211 VAL D C   1 
ATOM   1611  O  O   . VAL A 1 264 ? 101.051 124.043 99.556  1.00 37.31  ? 211 VAL D O   1 
ATOM   1612  C  CB  . VAL A 1 264 ? 98.574  123.051 97.892  1.00 32.45  ? 211 VAL D CB  1 
ATOM   1613  C  CG1 . VAL A 1 264 ? 98.054  121.839 98.635  1.00 30.86  ? 211 VAL D CG1 1 
ATOM   1614  C  CG2 . VAL A 1 264 ? 97.627  123.427 96.782  1.00 34.66  ? 211 VAL D CG2 1 
ATOM   1615  N  N   . VAL A 1 265 ? 99.468  123.598 101.090 1.00 32.97  ? 212 VAL D N   1 
ATOM   1616  C  CA  . VAL A 1 265 ? 100.399 123.270 102.161 1.00 32.64  ? 212 VAL D CA  1 
ATOM   1617  C  C   . VAL A 1 265 ? 100.086 121.871 102.661 1.00 35.09  ? 212 VAL D C   1 
ATOM   1618  O  O   . VAL A 1 265 ? 98.922  121.545 102.913 1.00 39.66  ? 212 VAL D O   1 
ATOM   1619  C  CB  . VAL A 1 265 ? 100.320 124.275 103.320 1.00 33.59  ? 212 VAL D CB  1 
ATOM   1620  C  CG1 . VAL A 1 265 ? 101.466 124.060 104.280 1.00 32.00  ? 212 VAL D CG1 1 
ATOM   1621  C  CG2 . VAL A 1 265 ? 100.339 125.667 102.790 1.00 38.63  ? 212 VAL D CG2 1 
ATOM   1622  N  N   . MET A 1 266 ? 101.119 121.050 102.802 1.00 31.56  ? 213 MET D N   1 
ATOM   1623  C  CA  . MET A 1 266 ? 101.006 119.732 103.403 1.00 30.57  ? 213 MET D CA  1 
ATOM   1624  C  C   . MET A 1 266 ? 101.647 119.777 104.779 1.00 31.42  ? 213 MET D C   1 
ATOM   1625  O  O   . MET A 1 266 ? 102.754 120.301 104.932 1.00 31.86  ? 213 MET D O   1 
ATOM   1626  C  CB  . MET A 1 266 ? 101.676 118.676 102.528 1.00 31.59  ? 213 MET D CB  1 
ATOM   1627  C  CG  . MET A 1 266 ? 101.475 118.905 101.046 1.00 32.90  ? 213 MET D CG  1 
ATOM   1628  S  SD  . MET A 1 266 ? 99.766  118.716 100.520 1.00 50.98  ? 213 MET D SD  1 
ATOM   1629  C  CE  . MET A 1 266 ? 99.654  116.939 100.449 1.00 37.34  ? 213 MET D CE  1 
ATOM   1630  N  N   . THR A 1 267 ? 100.952 119.232 105.775 1.00 34.64  ? 214 THR D N   1 
ATOM   1631  C  CA  . THR A 1 267 ? 101.314 119.405 107.172 1.00 32.72  ? 214 THR D CA  1 
ATOM   1632  C  C   . THR A 1 267 ? 101.423 118.059 107.870 1.00 34.79  ? 214 THR D C   1 
ATOM   1633  O  O   . THR A 1 267 ? 100.586 117.175 107.673 1.00 39.67  ? 214 THR D O   1 
ATOM   1634  C  CB  . THR A 1 267 ? 100.279 120.264 107.894 1.00 33.63  ? 214 THR D CB  1 
ATOM   1635  O  OG1 . THR A 1 267 ? 100.039 121.458 107.144 1.00 35.31  ? 214 THR D OG1 1 
ATOM   1636  C  CG2 . THR A 1 267 ? 100.772 120.637 109.266 1.00 36.97  ? 214 THR D CG2 1 
ATOM   1637  N  N   . THR A 1 268 ? 102.457 117.918 108.692 1.00 33.77  ? 215 THR D N   1 
ATOM   1638  C  CA  . THR A 1 268 ? 102.630 116.766 109.564 1.00 33.39  ? 215 THR D CA  1 
ATOM   1639  C  C   . THR A 1 268 ? 102.846 117.267 110.982 1.00 37.57  ? 215 THR D C   1 
ATOM   1640  O  O   . THR A 1 268 ? 103.722 118.097 111.214 1.00 41.94  ? 215 THR D O   1 
ATOM   1641  C  CB  . THR A 1 268 ? 103.819 115.913 109.125 1.00 34.58  ? 215 THR D CB  1 
ATOM   1642  O  OG1 . THR A 1 268 ? 103.730 115.656 107.721 1.00 43.22  ? 215 THR D OG1 1 
ATOM   1643  C  CG2 . THR A 1 268 ? 103.833 114.602 109.871 1.00 35.65  ? 215 THR D CG2 1 
ATOM   1644  N  N   . HIS A 1 269 ? 102.051 116.781 111.926 1.00 36.80  ? 216 HIS D N   1 
ATOM   1645  C  CA  . HIS A 1 269 ? 102.215 117.124 113.333 1.00 33.85  ? 216 HIS D CA  1 
ATOM   1646  C  C   . HIS A 1 269 ? 102.754 115.909 114.068 1.00 34.03  ? 216 HIS D C   1 
ATOM   1647  O  O   . HIS A 1 269 ? 102.115 114.856 114.070 1.00 39.89  ? 216 HIS D O   1 
ATOM   1648  C  CB  . HIS A 1 269 ? 100.896 117.577 113.955 1.00 37.06  ? 216 HIS D CB  1 
ATOM   1649  C  CG  . HIS A 1 269 ? 100.479 118.957 113.557 1.00 42.52  ? 216 HIS D CG  1 
ATOM   1650  N  ND1 . HIS A 1 269 ? 99.659  119.205 112.480 1.00 48.73  ? 216 HIS D ND1 1 
ATOM   1651  C  CD2 . HIS A 1 269 ? 100.770 120.163 114.094 1.00 42.94  ? 216 HIS D CD2 1 
ATOM   1652  C  CE1 . HIS A 1 269 ? 99.463  120.506 112.370 1.00 49.72  ? 216 HIS D CE1 1 
ATOM   1653  N  NE2 . HIS A 1 269 ? 100.129 121.111 113.336 1.00 47.78  ? 216 HIS D NE2 1 
ATOM   1654  N  N   . PHE A 1 270 ? 103.916 116.055 114.691 1.00 31.59  ? 217 PHE D N   1 
ATOM   1655  C  CA  . PHE A 1 270 ? 104.496 115.010 115.522 1.00 33.74  ? 217 PHE D CA  1 
ATOM   1656  C  C   . PHE A 1 270 ? 104.152 115.312 116.972 1.00 36.58  ? 217 PHE D C   1 
ATOM   1657  O  O   . PHE A 1 270 ? 104.481 116.390 117.473 1.00 41.18  ? 217 PHE D O   1 
ATOM   1658  C  CB  . PHE A 1 270 ? 106.011 114.935 115.336 1.00 35.78  ? 217 PHE D CB  1 
ATOM   1659  C  CG  . PHE A 1 270 ? 106.435 114.637 113.931 1.00 36.45  ? 217 PHE D CG  1 
ATOM   1660  C  CD1 . PHE A 1 270 ? 106.580 113.335 113.502 1.00 35.61  ? 217 PHE D CD1 1 
ATOM   1661  C  CD2 . PHE A 1 270 ? 106.689 115.659 113.040 1.00 34.74  ? 217 PHE D CD2 1 
ATOM   1662  C  CE1 . PHE A 1 270 ? 106.964 113.061 112.215 1.00 36.32  ? 217 PHE D CE1 1 
ATOM   1663  C  CE2 . PHE A 1 270 ? 107.076 115.386 111.749 1.00 31.02  ? 217 PHE D CE2 1 
ATOM   1664  C  CZ  . PHE A 1 270 ? 107.215 114.087 111.338 1.00 34.27  ? 217 PHE D CZ  1 
ATOM   1665  N  N   . HIS A 1 271 ? 103.488 114.371 117.641 1.00 35.65  ? 218 HIS D N   1 
ATOM   1666  C  CA  . HIS A 1 271 ? 102.993 114.594 118.996 1.00 36.75  ? 218 HIS D CA  1 
ATOM   1667  C  C   . HIS A 1 271 ? 104.017 114.083 120.001 1.00 37.43  ? 218 HIS D C   1 
ATOM   1668  O  O   . HIS A 1 271 ? 104.247 112.876 120.105 1.00 38.95  ? 218 HIS D O   1 
ATOM   1669  C  CB  . HIS A 1 271 ? 101.647 113.908 119.196 1.00 36.19  ? 218 HIS D CB  1 
ATOM   1670  C  CG  . HIS A 1 271 ? 100.619 114.295 118.183 1.00 36.27  ? 218 HIS D CG  1 
ATOM   1671  N  ND1 . HIS A 1 271 ? 100.063 115.553 118.132 1.00 36.80  ? 218 HIS D ND1 1 
ATOM   1672  C  CD2 . HIS A 1 271 ? 100.047 113.590 117.182 1.00 36.13  ? 218 HIS D CD2 1 
ATOM   1673  C  CE1 . HIS A 1 271 ? 99.193  115.607 117.142 1.00 37.95  ? 218 HIS D CE1 1 
ATOM   1674  N  NE2 . HIS A 1 271 ? 99.163  114.428 116.551 1.00 39.81  ? 218 HIS D NE2 1 
ATOM   1675  N  N   . LEU A 1 272 ? 104.596 114.999 120.769 1.00 36.42  ? 219 LEU D N   1 
ATOM   1676  C  CA  . LEU A 1 272 ? 105.604 114.678 121.765 1.00 34.62  ? 219 LEU D CA  1 
ATOM   1677  C  C   . LEU A 1 272 ? 105.054 114.910 123.163 1.00 36.18  ? 219 LEU D C   1 
ATOM   1678  O  O   . LEU A 1 272 ? 104.331 115.882 123.403 1.00 41.70  ? 219 LEU D O   1 
ATOM   1679  C  CB  . LEU A 1 272 ? 106.854 115.531 121.581 1.00 30.92  ? 219 LEU D CB  1 
ATOM   1680  C  CG  . LEU A 1 272 ? 107.541 115.541 120.228 1.00 30.34  ? 219 LEU D CG  1 
ATOM   1681  C  CD1 . LEU A 1 272 ? 108.518 116.671 120.222 1.00 33.56  ? 219 LEU D CD1 1 
ATOM   1682  C  CD2 . LEU A 1 272 ? 108.242 114.235 119.989 1.00 30.88  ? 219 LEU D CD2 1 
ATOM   1683  N  N   . LYS A 1 273 ? 105.403 114.014 124.079 1.00 32.16  ? 220 LYS D N   1 
ATOM   1684  C  CA  . LYS A 1 273 ? 105.095 114.162 125.491 1.00 34.90  ? 220 LYS D CA  1 
ATOM   1685  C  C   . LYS A 1 273 ? 106.390 114.068 126.276 1.00 38.42  ? 220 LYS D C   1 
ATOM   1686  O  O   . LYS A 1 273 ? 107.173 113.138 126.071 1.00 43.09  ? 220 LYS D O   1 
ATOM   1687  C  CB  . LYS A 1 273 ? 104.109 113.096 125.967 1.00 36.35  ? 220 LYS D CB  1 
ATOM   1688  C  CG  . LYS A 1 273 ? 103.471 113.433 127.292 1.00 42.27  ? 220 LYS D CG  1 
ATOM   1689  C  CD  . LYS A 1 273 ? 102.471 112.388 127.723 1.00 46.57  ? 220 LYS D CD  1 
ATOM   1690  C  CE  . LYS A 1 273 ? 101.647 112.901 128.887 1.00 58.02  ? 220 LYS D CE  1 
ATOM   1691  N  NZ  . LYS A 1 273 ? 102.492 113.611 129.884 1.00 57.52  ? 220 LYS D NZ  1 
ATOM   1692  N  N   . ARG A 1 274 ? 106.612 115.019 127.173 1.00 37.24  ? 221 ARG D N   1 
ATOM   1693  C  CA  . ARG A 1 274 ? 107.873 115.079 127.892 1.00 35.74  ? 221 ARG D CA  1 
ATOM   1694  C  C   . ARG A 1 274 ? 107.963 113.982 128.943 1.00 36.79  ? 221 ARG D C   1 
ATOM   1695  O  O   . ARG A 1 274 ? 106.983 113.666 129.620 1.00 40.49  ? 221 ARG D O   1 
ATOM   1696  C  CB  . ARG A 1 274 ? 108.036 116.441 128.553 1.00 34.00  ? 221 ARG D CB  1 
ATOM   1697  C  CG  . ARG A 1 274 ? 109.364 116.620 129.228 1.00 36.95  ? 221 ARG D CG  1 
ATOM   1698  C  CD  . ARG A 1 274 ? 109.420 117.928 129.956 1.00 38.68  ? 221 ARG D CD  1 
ATOM   1699  N  NE  . ARG A 1 274 ? 109.374 119.057 129.040 1.00 38.22  ? 221 ARG D NE  1 
ATOM   1700  C  CZ  . ARG A 1 274 ? 110.447 119.645 128.537 1.00 39.76  ? 221 ARG D CZ  1 
ATOM   1701  N  NH1 . ARG A 1 274 ? 111.664 119.224 128.831 1.00 42.31  ? 221 ARG D NH1 1 
ATOM   1702  N  NH2 . ARG A 1 274 ? 110.295 120.678 127.717 1.00 38.94  ? 221 ARG D NH2 1 
ATOM   1703  N  N   . LYS A 1 275 ? 109.151 113.397 129.073 1.00 37.78  ? 222 LYS D N   1 
ATOM   1704  C  CA  . LYS A 1 275 ? 109.411 112.444 130.143 1.00 37.41  ? 222 LYS D CA  1 
ATOM   1705  C  C   . LYS A 1 275 ? 109.496 113.172 131.476 1.00 41.99  ? 222 LYS D C   1 
ATOM   1706  O  O   . LYS A 1 275 ? 110.201 114.176 131.598 1.00 46.02  ? 222 LYS D O   1 
ATOM   1707  C  CB  . LYS A 1 275 ? 110.710 111.691 129.878 1.00 34.92  ? 222 LYS D CB  1 
ATOM   1708  C  CG  . LYS A 1 275 ? 110.692 110.776 128.672 1.00 35.82  ? 222 LYS D CG  1 
ATOM   1709  C  CD  . LYS A 1 275 ? 112.058 110.145 128.486 1.00 37.36  ? 222 LYS D CD  1 
ATOM   1710  C  CE  . LYS A 1 275 ? 112.011 108.947 127.564 1.00 41.31  ? 222 LYS D CE  1 
ATOM   1711  N  NZ  . LYS A 1 275 ? 111.928 109.327 126.131 1.00 48.92  ? 222 LYS D NZ  1 
ATOM   1712  N  N   . ILE A 1 276 ? 108.803 112.653 132.485 1.00 39.37  ? 223 ILE D N   1 
ATOM   1713  C  CA  . ILE A 1 276 ? 108.659 113.358 133.751 1.00 38.28  ? 223 ILE D CA  1 
ATOM   1714  C  C   . ILE A 1 276 ? 109.462 112.734 134.885 1.00 41.70  ? 223 ILE D C   1 
ATOM   1715  O  O   . ILE A 1 276 ? 109.669 113.402 135.908 1.00 46.39  ? 223 ILE D O   1 
ATOM   1716  C  CB  . ILE A 1 276 ? 107.176 113.469 134.156 1.00 36.37  ? 223 ILE D CB  1 
ATOM   1717  C  CG1 . ILE A 1 276 ? 106.975 114.619 135.142 1.00 43.00  ? 223 ILE D CG1 1 
ATOM   1718  C  CG2 . ILE A 1 276 ? 106.699 112.168 134.767 1.00 35.23  ? 223 ILE D CG2 1 
ATOM   1719  C  CD1 . ILE A 1 276 ? 105.648 114.589 135.847 1.00 46.87  ? 223 ILE D CD1 1 
ATOM   1720  N  N   . GLY A 1 277 ? 109.938 111.496 134.739 1.00 39.99  ? 224 GLY D N   1 
ATOM   1721  C  CA  . GLY A 1 277 ? 110.593 110.827 135.854 1.00 39.20  ? 224 GLY D CA  1 
ATOM   1722  C  C   . GLY A 1 277 ? 111.815 111.568 136.361 1.00 44.18  ? 224 GLY D C   1 
ATOM   1723  O  O   . GLY A 1 277 ? 112.083 111.592 137.567 1.00 50.71  ? 224 GLY D O   1 
ATOM   1724  N  N   . TYR A 1 278 ? 112.569 112.185 135.451 1.00 41.29  ? 225 TYR D N   1 
ATOM   1725  C  CA  . TYR A 1 278 ? 113.764 112.922 135.844 1.00 43.22  ? 225 TYR D CA  1 
ATOM   1726  C  C   . TYR A 1 278 ? 113.426 114.017 136.842 1.00 46.66  ? 225 TYR D C   1 
ATOM   1727  O  O   . TYR A 1 278 ? 114.113 114.187 137.853 1.00 48.77  ? 225 TYR D O   1 
ATOM   1728  C  CB  . TYR A 1 278 ? 114.431 113.519 134.610 1.00 46.65  ? 225 TYR D CB  1 
ATOM   1729  C  CG  . TYR A 1 278 ? 115.562 114.477 134.902 1.00 49.60  ? 225 TYR D CG  1 
ATOM   1730  C  CD1 . TYR A 1 278 ? 116.837 114.013 135.173 1.00 53.22  ? 225 TYR D CD1 1 
ATOM   1731  C  CD2 . TYR A 1 278 ? 115.358 115.846 134.879 1.00 47.82  ? 225 TYR D CD2 1 
ATOM   1732  C  CE1 . TYR A 1 278 ? 117.872 114.884 135.428 1.00 56.55  ? 225 TYR D CE1 1 
ATOM   1733  C  CE2 . TYR A 1 278 ? 116.385 116.723 135.132 1.00 51.00  ? 225 TYR D CE2 1 
ATOM   1734  C  CZ  . TYR A 1 278 ? 117.639 116.239 135.405 1.00 58.18  ? 225 TYR D CZ  1 
ATOM   1735  O  OH  . TYR A 1 278 ? 118.664 117.119 135.660 1.00 63.83  ? 225 TYR D OH  1 
ATOM   1736  N  N   . PHE A 1 279 ? 112.359 114.766 136.577 1.00 48.68  ? 226 PHE D N   1 
ATOM   1737  C  CA  . PHE A 1 279 ? 111.987 115.844 137.481 1.00 45.99  ? 226 PHE D CA  1 
ATOM   1738  C  C   . PHE A 1 279 ? 111.351 115.313 138.754 1.00 46.45  ? 226 PHE D C   1 
ATOM   1739  O  O   . PHE A 1 279 ? 111.462 115.948 139.806 1.00 51.37  ? 226 PHE D O   1 
ATOM   1740  C  CB  . PHE A 1 279 ? 111.054 116.817 136.769 1.00 42.48  ? 226 PHE D CB  1 
ATOM   1741  C  CG  . PHE A 1 279 ? 111.646 117.403 135.529 1.00 43.42  ? 226 PHE D CG  1 
ATOM   1742  C  CD1 . PHE A 1 279 ? 112.486 118.496 135.600 1.00 43.02  ? 226 PHE D CD1 1 
ATOM   1743  C  CD2 . PHE A 1 279 ? 111.388 116.845 134.294 1.00 41.46  ? 226 PHE D CD2 1 
ATOM   1744  C  CE1 . PHE A 1 279 ? 113.044 119.031 134.463 1.00 41.57  ? 226 PHE D CE1 1 
ATOM   1745  C  CE2 . PHE A 1 279 ? 111.945 117.377 133.154 1.00 42.22  ? 226 PHE D CE2 1 
ATOM   1746  C  CZ  . PHE A 1 279 ? 112.777 118.470 133.240 1.00 44.20  ? 226 PHE D CZ  1 
ATOM   1747  N  N   . VAL A 1 280 ? 110.691 114.157 138.687 1.00 43.58  ? 227 VAL D N   1 
ATOM   1748  C  CA  . VAL A 1 280 ? 110.120 113.571 139.895 1.00 44.69  ? 227 VAL D CA  1 
ATOM   1749  C  C   . VAL A 1 280 ? 111.223 113.194 140.872 1.00 47.57  ? 227 VAL D C   1 
ATOM   1750  O  O   . VAL A 1 280 ? 111.135 113.477 142.070 1.00 52.09  ? 227 VAL D O   1 
ATOM   1751  C  CB  . VAL A 1 280 ? 109.236 112.361 139.552 1.00 44.17  ? 227 VAL D CB  1 
ATOM   1752  C  CG1 . VAL A 1 280 ? 108.909 111.590 140.811 1.00 43.01  ? 227 VAL D CG1 1 
ATOM   1753  C  CG2 . VAL A 1 280 ? 107.964 112.822 138.884 1.00 43.33  ? 227 VAL D CG2 1 
ATOM   1754  N  N   . ILE A 1 281 ? 112.290 112.560 140.377 1.00 46.11  ? 228 ILE D N   1 
ATOM   1755  C  CA  . ILE A 1 281 ? 113.381 112.185 141.271 1.00 50.00  ? 228 ILE D CA  1 
ATOM   1756  C  C   . ILE A 1 281 ? 114.418 113.284 141.416 1.00 50.95  ? 228 ILE D C   1 
ATOM   1757  O  O   . ILE A 1 281 ? 115.395 113.106 142.153 1.00 56.79  ? 228 ILE D O   1 
ATOM   1758  C  CB  . ILE A 1 281 ? 114.091 110.891 140.821 1.00 50.67  ? 228 ILE D CB  1 
ATOM   1759  C  CG1 . ILE A 1 281 ? 114.929 111.145 139.571 1.00 50.97  ? 228 ILE D CG1 1 
ATOM   1760  C  CG2 . ILE A 1 281 ? 113.084 109.780 140.581 1.00 51.09  ? 228 ILE D CG2 1 
ATOM   1761  C  CD1 . ILE A 1 281 ? 115.657 109.914 139.076 1.00 49.70  ? 228 ILE D CD1 1 
ATOM   1762  N  N   . GLN A 1 282 ? 114.237 114.417 140.751 1.00 50.10  ? 229 GLN D N   1 
ATOM   1763  C  CA  . GLN A 1 282 ? 115.196 115.510 140.813 1.00 52.57  ? 229 GLN D CA  1 
ATOM   1764  C  C   . GLN A 1 282 ? 114.664 116.744 141.521 1.00 56.76  ? 229 GLN D C   1 
ATOM   1765  O  O   . GLN A 1 282 ? 115.425 117.431 142.201 1.00 56.32  ? 229 GLN D O   1 
ATOM   1766  C  CB  . GLN A 1 282 ? 115.642 115.888 139.396 1.00 52.93  ? 229 GLN D CB  1 
ATOM   1767  C  CG  . GLN A 1 282 ? 116.662 117.007 139.326 1.00 56.35  ? 229 GLN D CG  1 
ATOM   1768  C  CD  . GLN A 1 282 ? 118.058 116.550 139.679 1.00 65.89  ? 229 GLN D CD  1 
ATOM   1769  O  OE1 . GLN A 1 282 ? 118.951 117.365 139.905 1.00 69.25  ? 229 GLN D OE1 1 
ATOM   1770  N  NE2 . GLN A 1 282 ? 118.260 115.239 139.723 1.00 66.06  ? 229 GLN D NE2 1 
ATOM   1771  N  N   . THR A 1 283 ? 113.377 117.055 141.380 1.00 55.08  ? 230 THR D N   1 
ATOM   1772  C  CA  . THR A 1 283 ? 112.816 118.244 142.007 1.00 48.81  ? 230 THR D CA  1 
ATOM   1773  C  C   . THR A 1 283 ? 111.657 117.949 142.946 1.00 47.73  ? 230 THR D C   1 
ATOM   1774  O  O   . THR A 1 283 ? 111.641 118.460 144.068 1.00 51.97  ? 230 THR D O   1 
ATOM   1775  C  CB  . THR A 1 283 ? 112.374 119.242 140.933 1.00 51.15  ? 230 THR D CB  1 
ATOM   1776  O  OG1 . THR A 1 283 ? 113.529 119.762 140.264 1.00 52.18  ? 230 THR D OG1 1 
ATOM   1777  C  CG2 . THR A 1 283 ? 111.602 120.383 141.559 1.00 49.13  ? 230 THR D CG2 1 
ATOM   1778  N  N   . TYR A 1 284 ? 110.680 117.146 142.526 1.00 44.39  ? 231 TYR D N   1 
ATOM   1779  C  CA  . TYR A 1 284 ? 109.476 116.972 143.335 1.00 45.04  ? 231 TYR D CA  1 
ATOM   1780  C  C   . TYR A 1 284 ? 109.766 116.207 144.622 1.00 50.56  ? 231 TYR D C   1 
ATOM   1781  O  O   . TYR A 1 284 ? 109.282 116.579 145.698 1.00 52.17  ? 231 TYR D O   1 
ATOM   1782  C  CB  . TYR A 1 284 ? 108.395 116.264 142.524 1.00 45.62  ? 231 TYR D CB  1 
ATOM   1783  C  CG  . TYR A 1 284 ? 107.703 117.149 141.517 1.00 48.02  ? 231 TYR D CG  1 
ATOM   1784  C  CD1 . TYR A 1 284 ? 106.640 117.949 141.891 1.00 46.07  ? 231 TYR D CD1 1 
ATOM   1785  C  CD2 . TYR A 1 284 ? 108.103 117.175 140.191 1.00 49.14  ? 231 TYR D CD2 1 
ATOM   1786  C  CE1 . TYR A 1 284 ? 106.003 118.753 140.983 1.00 45.32  ? 231 TYR D CE1 1 
ATOM   1787  C  CE2 . TYR A 1 284 ? 107.466 117.977 139.274 1.00 44.57  ? 231 TYR D CE2 1 
ATOM   1788  C  CZ  . TYR A 1 284 ? 106.417 118.764 139.678 1.00 43.73  ? 231 TYR D CZ  1 
ATOM   1789  O  OH  . TYR A 1 284 ? 105.770 119.569 138.776 1.00 46.42  ? 231 TYR D OH  1 
ATOM   1790  N  N   . LEU A 1 285 ? 110.528 115.119 144.527 1.00 49.88  ? 232 LEU D N   1 
ATOM   1791  C  CA  . LEU A 1 285 ? 110.842 114.333 145.720 1.00 46.06  ? 232 LEU D CA  1 
ATOM   1792  C  C   . LEU A 1 285 ? 111.625 115.115 146.764 1.00 47.64  ? 232 LEU D C   1 
ATOM   1793  O  O   . LEU A 1 285 ? 111.290 115.002 147.956 1.00 49.64  ? 232 LEU D O   1 
ATOM   1794  C  CB  . LEU A 1 285 ? 111.580 113.052 145.325 1.00 45.03  ? 232 LEU D CB  1 
ATOM   1795  C  CG  . LEU A 1 285 ? 110.703 111.832 145.070 1.00 48.77  ? 232 LEU D CG  1 
ATOM   1796  C  CD1 . LEU A 1 285 ? 111.570 110.602 144.947 1.00 50.89  ? 232 LEU D CD1 1 
ATOM   1797  C  CD2 . LEU A 1 285 ? 109.685 111.662 146.175 1.00 44.43  ? 232 LEU D CD2 1 
ATOM   1798  N  N   . PRO A 1 286 ? 112.682 115.865 146.427 1.00 45.83  ? 233 PRO D N   1 
ATOM   1799  C  CA  . PRO A 1 286 ? 113.331 116.669 147.473 1.00 45.03  ? 233 PRO D CA  1 
ATOM   1800  C  C   . PRO A 1 286 ? 112.390 117.650 148.145 1.00 45.70  ? 233 PRO D C   1 
ATOM   1801  O  O   . PRO A 1 286 ? 112.454 117.816 149.367 1.00 50.61  ? 233 PRO D O   1 
ATOM   1802  C  CB  . PRO A 1 286 ? 114.454 117.379 146.711 1.00 39.38  ? 233 PRO D CB  1 
ATOM   1803  C  CG  . PRO A 1 286 ? 114.765 116.478 145.600 1.00 43.09  ? 233 PRO D CG  1 
ATOM   1804  C  CD  . PRO A 1 286 ? 113.456 115.899 145.174 1.00 43.63  ? 233 PRO D CD  1 
ATOM   1805  N  N   . CYS A 1 287 ? 111.497 118.287 147.387 1.00 42.37  ? 234 CYS D N   1 
ATOM   1806  C  CA  . CYS A 1 287 ? 110.559 119.227 147.989 1.00 42.39  ? 234 CYS D CA  1 
ATOM   1807  C  C   . CYS A 1 287 ? 109.593 118.525 148.933 1.00 43.72  ? 234 CYS D C   1 
ATOM   1808  O  O   . CYS A 1 287 ? 109.321 119.019 150.034 1.00 48.90  ? 234 CYS D O   1 
ATOM   1809  C  CB  . CYS A 1 287 ? 109.794 119.976 146.900 1.00 44.21  ? 234 CYS D CB  1 
ATOM   1810  S  SG  . CYS A 1 287 ? 110.812 121.064 145.888 1.00 59.14  ? 234 CYS D SG  1 
ATOM   1811  N  N   . ILE A 1 288 ? 109.067 117.370 148.526 1.00 45.29  ? 235 ILE D N   1 
ATOM   1812  C  CA  . ILE A 1 288 ? 108.134 116.649 149.385 1.00 47.36  ? 235 ILE D CA  1 
ATOM   1813  C  C   . ILE A 1 288 ? 108.832 116.162 150.649 1.00 51.02  ? 235 ILE D C   1 
ATOM   1814  O  O   . ILE A 1 288 ? 108.285 116.263 151.755 1.00 55.35  ? 235 ILE D O   1 
ATOM   1815  C  CB  . ILE A 1 288 ? 107.481 115.492 148.611 1.00 46.45  ? 235 ILE D CB  1 
ATOM   1816  C  CG1 . ILE A 1 288 ? 106.656 116.039 147.449 1.00 47.30  ? 235 ILE D CG1 1 
ATOM   1817  C  CG2 . ILE A 1 288 ? 106.602 114.677 149.528 1.00 42.78  ? 235 ILE D CG2 1 
ATOM   1818  C  CD1 . ILE A 1 288 ? 106.059 114.974 146.578 1.00 46.08  ? 235 ILE D CD1 1 
ATOM   1819  N  N   . MET A 1 289 ? 110.051 115.636 150.513 1.00 49.09  ? 236 MET D N   1 
ATOM   1820  C  CA  . MET A 1 289 ? 110.790 115.193 151.689 1.00 52.14  ? 236 MET D CA  1 
ATOM   1821  C  C   . MET A 1 289 ? 111.081 116.356 152.627 1.00 52.18  ? 236 MET D C   1 
ATOM   1822  O  O   . MET A 1 289 ? 110.977 116.214 153.850 1.00 54.46  ? 236 MET D O   1 
ATOM   1823  C  CB  . MET A 1 289 ? 112.090 114.505 151.274 1.00 56.29  ? 236 MET D CB  1 
ATOM   1824  C  CG  . MET A 1 289 ? 111.904 113.147 150.620 1.00 67.35  ? 236 MET D CG  1 
ATOM   1825  S  SD  . MET A 1 289 ? 110.964 111.988 151.631 1.00 95.62  ? 236 MET D SD  1 
ATOM   1826  C  CE  . MET A 1 289 ? 112.007 111.863 153.083 1.00 77.06  ? 236 MET D CE  1 
ATOM   1827  N  N   . THR A 1 290 ? 111.450 117.515 152.077 1.00 49.36  ? 237 THR D N   1 
ATOM   1828  C  CA  . THR A 1 290 ? 111.728 118.676 152.913 1.00 47.22  ? 237 THR D CA  1 
ATOM   1829  C  C   . THR A 1 290 ? 110.480 119.128 153.660 1.00 47.89  ? 237 THR D C   1 
ATOM   1830  O  O   . THR A 1 290 ? 110.545 119.479 154.842 1.00 53.59  ? 237 THR D O   1 
ATOM   1831  C  CB  . THR A 1 290 ? 112.288 119.814 152.061 1.00 41.95  ? 237 THR D CB  1 
ATOM   1832  O  OG1 . THR A 1 290 ? 113.374 119.326 151.269 1.00 45.26  ? 237 THR D OG1 1 
ATOM   1833  C  CG2 . THR A 1 290 ? 112.796 120.922 152.939 1.00 40.70  ? 237 THR D CG2 1 
ATOM   1834  N  N   . VAL A 1 291 ? 109.329 119.131 152.986 1.00 43.74  ? 238 VAL D N   1 
ATOM   1835  C  CA  . VAL A 1 291 ? 108.092 119.528 153.655 1.00 44.41  ? 238 VAL D CA  1 
ATOM   1836  C  C   . VAL A 1 291 ? 107.752 118.551 154.773 1.00 50.56  ? 238 VAL D C   1 
ATOM   1837  O  O   . VAL A 1 291 ? 107.345 118.956 155.871 1.00 57.49  ? 238 VAL D O   1 
ATOM   1838  C  CB  . VAL A 1 291 ? 106.942 119.651 152.640 1.00 43.57  ? 238 VAL D CB  1 
ATOM   1839  C  CG1 . VAL A 1 291 ? 105.630 119.851 153.360 1.00 45.65  ? 238 VAL D CG1 1 
ATOM   1840  C  CG2 . VAL A 1 291 ? 107.191 120.809 151.709 1.00 42.62  ? 238 VAL D CG2 1 
ATOM   1841  N  N   . ILE A 1 292 ? 107.914 117.252 154.518 1.00 49.29  ? 239 ILE D N   1 
ATOM   1842  C  CA  . ILE A 1 292 ? 107.627 116.255 155.548 1.00 50.76  ? 239 ILE D CA  1 
ATOM   1843  C  C   . ILE A 1 292 ? 108.549 116.446 156.747 1.00 52.38  ? 239 ILE D C   1 
ATOM   1844  O  O   . ILE A 1 292 ? 108.109 116.419 157.904 1.00 52.20  ? 239 ILE D O   1 
ATOM   1845  C  CB  . ILE A 1 292 ? 107.741 114.837 154.966 1.00 49.48  ? 239 ILE D CB  1 
ATOM   1846  C  CG1 . ILE A 1 292 ? 106.588 114.570 153.999 1.00 46.43  ? 239 ILE D CG1 1 
ATOM   1847  C  CG2 . ILE A 1 292 ? 107.763 113.807 156.075 1.00 51.36  ? 239 ILE D CG2 1 
ATOM   1848  C  CD1 . ILE A 1 292 ? 106.634 113.211 153.379 1.00 49.26  ? 239 ILE D CD1 1 
ATOM   1849  N  N   . LEU A 1 293 ? 109.841 116.652 156.489 1.00 51.45  ? 240 LEU D N   1 
ATOM   1850  C  CA  . LEU A 1 293 ? 110.782 116.886 157.576 1.00 48.66  ? 240 LEU D CA  1 
ATOM   1851  C  C   . LEU A 1 293 ? 110.453 118.146 158.361 1.00 50.73  ? 240 LEU D C   1 
ATOM   1852  O  O   . LEU A 1 293 ? 110.587 118.146 159.587 1.00 54.81  ? 240 LEU D O   1 
ATOM   1853  C  CB  . LEU A 1 293 ? 112.209 116.975 157.040 1.00 46.52  ? 240 LEU D CB  1 
ATOM   1854  C  CG  . LEU A 1 293 ? 112.833 115.698 156.483 1.00 50.09  ? 240 LEU D CG  1 
ATOM   1855  C  CD1 . LEU A 1 293 ? 114.243 115.980 156.005 1.00 47.18  ? 240 LEU D CD1 1 
ATOM   1856  C  CD2 . LEU A 1 293 ? 112.832 114.600 157.524 1.00 51.28  ? 240 LEU D CD2 1 
ATOM   1857  N  N   . SER A 1 294 ? 110.035 119.217 157.688 1.00 47.43  ? 241 SER D N   1 
ATOM   1858  C  CA  . SER A 1 294 ? 109.644 120.429 158.395 1.00 46.21  ? 241 SER D CA  1 
ATOM   1859  C  C   . SER A 1 294 ? 108.426 120.196 159.273 1.00 52.25  ? 241 SER D C   1 
ATOM   1860  O  O   . SER A 1 294 ? 108.350 120.727 160.384 1.00 56.09  ? 241 SER D O   1 
ATOM   1861  C  CB  . SER A 1 294 ? 109.361 121.552 157.403 1.00 42.90  ? 241 SER D CB  1 
ATOM   1862  O  OG  . SER A 1 294 ? 108.142 121.327 156.724 1.00 50.29  ? 241 SER D OG  1 
ATOM   1863  N  N   . GLN A 1 295 ? 107.456 119.421 158.789 1.00 53.50  ? 242 GLN D N   1 
ATOM   1864  C  CA  . GLN A 1 295 ? 106.272 119.156 159.598 1.00 54.48  ? 242 GLN D CA  1 
ATOM   1865  C  C   . GLN A 1 295 ? 106.538 118.154 160.712 1.00 58.80  ? 242 GLN D C   1 
ATOM   1866  O  O   . GLN A 1 295 ? 105.727 118.048 161.636 1.00 61.51  ? 242 GLN D O   1 
ATOM   1867  C  CB  . GLN A 1 295 ? 105.127 118.667 158.716 1.00 54.28  ? 242 GLN D CB  1 
ATOM   1868  C  CG  . GLN A 1 295 ? 104.625 119.714 157.752 1.00 56.23  ? 242 GLN D CG  1 
ATOM   1869  C  CD  . GLN A 1 295 ? 103.483 119.218 156.904 1.00 61.98  ? 242 GLN D CD  1 
ATOM   1870  O  OE1 . GLN A 1 295 ? 102.992 119.931 156.033 1.00 62.18  ? 242 GLN D OE1 1 
ATOM   1871  N  NE2 . GLN A 1 295 ? 103.048 117.992 157.155 1.00 64.57  ? 242 GLN D NE2 1 
ATOM   1872  N  N   . VAL A 1 296 ? 107.644 117.414 160.644 1.00 59.63  ? 243 VAL D N   1 
ATOM   1873  C  CA  . VAL A 1 296 ? 107.965 116.475 161.718 1.00 62.77  ? 243 VAL D CA  1 
ATOM   1874  C  C   . VAL A 1 296 ? 108.201 117.212 163.033 1.00 64.05  ? 243 VAL D C   1 
ATOM   1875  O  O   . VAL A 1 296 ? 107.838 116.723 164.110 1.00 68.02  ? 243 VAL D O   1 
ATOM   1876  C  CB  . VAL A 1 296 ? 109.173 115.603 161.328 1.00 59.75  ? 243 VAL D CB  1 
ATOM   1877  C  CG1 . VAL A 1 296 ? 109.899 115.104 162.561 1.00 57.10  ? 243 VAL D CG1 1 
ATOM   1878  C  CG2 . VAL A 1 296 ? 108.715 114.426 160.486 1.00 58.11  ? 243 VAL D CG2 1 
ATOM   1879  N  N   . SER A 1 297 ? 108.789 118.408 162.970 1.00 62.73  ? 244 SER D N   1 
ATOM   1880  C  CA  . SER A 1 297 ? 109.160 119.115 164.191 1.00 63.62  ? 244 SER D CA  1 
ATOM   1881  C  C   . SER A 1 297 ? 107.963 119.447 165.073 1.00 68.18  ? 244 SER D C   1 
ATOM   1882  O  O   . SER A 1 297 ? 108.149 119.726 166.260 1.00 73.84  ? 244 SER D O   1 
ATOM   1883  C  CB  . SER A 1 297 ? 109.920 120.397 163.850 1.00 64.85  ? 244 SER D CB  1 
ATOM   1884  O  OG  . SER A 1 297 ? 109.062 121.375 163.296 1.00 64.28  ? 244 SER D OG  1 
ATOM   1885  N  N   . PHE A 1 298 ? 106.743 119.430 164.533 1.00 67.75  ? 245 PHE D N   1 
ATOM   1886  C  CA  . PHE A 1 298 ? 105.572 119.690 165.365 1.00 68.88  ? 245 PHE D CA  1 
ATOM   1887  C  C   . PHE A 1 298 ? 105.393 118.644 166.454 1.00 72.18  ? 245 PHE D C   1 
ATOM   1888  O  O   . PHE A 1 298 ? 104.761 118.931 167.474 1.00 74.81  ? 245 PHE D O   1 
ATOM   1889  C  CB  . PHE A 1 298 ? 104.303 119.734 164.517 1.00 68.64  ? 245 PHE D CB  1 
ATOM   1890  C  CG  . PHE A 1 298 ? 104.318 120.783 163.456 1.00 69.54  ? 245 PHE D CG  1 
ATOM   1891  C  CD1 . PHE A 1 298 ? 104.979 121.977 163.648 1.00 68.66  ? 245 PHE D CD1 1 
ATOM   1892  C  CD2 . PHE A 1 298 ? 103.668 120.571 162.259 1.00 69.35  ? 245 PHE D CD2 1 
ATOM   1893  C  CE1 . PHE A 1 298 ? 104.987 122.937 162.666 1.00 65.23  ? 245 PHE D CE1 1 
ATOM   1894  C  CE2 . PHE A 1 298 ? 103.677 121.528 161.278 1.00 66.00  ? 245 PHE D CE2 1 
ATOM   1895  C  CZ  . PHE A 1 298 ? 104.335 122.713 161.483 1.00 63.72  ? 245 PHE D CZ  1 
ATOM   1896  N  N   . TRP A 1 299 ? 105.918 117.439 166.257 1.00 71.44  ? 246 TRP D N   1 
ATOM   1897  C  CA  . TRP A 1 299 ? 105.733 116.348 167.202 1.00 73.69  ? 246 TRP D CA  1 
ATOM   1898  C  C   . TRP A 1 299 ? 106.777 116.324 168.306 1.00 78.10  ? 246 TRP D C   1 
ATOM   1899  O  O   . TRP A 1 299 ? 106.639 115.538 169.247 1.00 82.84  ? 246 TRP D O   1 
ATOM   1900  C  CB  . TRP A 1 299 ? 105.749 115.012 166.458 1.00 74.21  ? 246 TRP D CB  1 
ATOM   1901  C  CG  . TRP A 1 299 ? 104.825 115.000 165.294 1.00 77.74  ? 246 TRP D CG  1 
ATOM   1902  C  CD1 . TRP A 1 299 ? 105.105 115.397 164.023 1.00 78.12  ? 246 TRP D CD1 1 
ATOM   1903  C  CD2 . TRP A 1 299 ? 103.462 114.575 165.291 1.00 79.49  ? 246 TRP D CD2 1 
ATOM   1904  N  NE1 . TRP A 1 299 ? 104.000 115.248 163.226 1.00 80.14  ? 246 TRP D NE1 1 
ATOM   1905  C  CE2 . TRP A 1 299 ? 102.976 114.742 163.982 1.00 81.12  ? 246 TRP D CE2 1 
ATOM   1906  C  CE3 . TRP A 1 299 ? 102.605 114.070 166.269 1.00 77.02  ? 246 TRP D CE3 1 
ATOM   1907  C  CZ2 . TRP A 1 299 ? 101.674 114.421 163.626 1.00 82.22  ? 246 TRP D CZ2 1 
ATOM   1908  C  CZ3 . TRP A 1 299 ? 101.315 113.753 165.914 1.00 82.61  ? 246 TRP D CZ3 1 
ATOM   1909  C  CH2 . TRP A 1 299 ? 100.860 113.928 164.603 1.00 86.07  ? 246 TRP D CH2 1 
ATOM   1910  N  N   . LEU A 1 300 ? 107.809 117.151 168.216 1.00 77.77  ? 247 LEU D N   1 
ATOM   1911  C  CA  . LEU A 1 300 ? 108.838 117.191 169.238 1.00 77.71  ? 247 LEU D CA  1 
ATOM   1912  C  C   . LEU A 1 300 ? 108.354 117.982 170.448 1.00 81.59  ? 247 LEU D C   1 
ATOM   1913  O  O   . LEU A 1 300 ? 107.405 118.764 170.373 1.00 81.07  ? 247 LEU D O   1 
ATOM   1914  C  CB  . LEU A 1 300 ? 110.121 117.809 168.682 1.00 72.68  ? 247 LEU D CB  1 
ATOM   1915  C  CG  . LEU A 1 300 ? 111.204 116.855 168.184 1.00 68.35  ? 247 LEU D CG  1 
ATOM   1916  C  CD1 . LEU A 1 300 ? 110.602 115.694 167.425 1.00 69.60  ? 247 LEU D CD1 1 
ATOM   1917  C  CD2 . LEU A 1 300 ? 112.177 117.604 167.305 1.00 67.20  ? 247 LEU D CD2 1 
ATOM   1918  N  N   . ASN A 1 301 ? 109.017 117.759 171.578 1.00 85.37  ? 248 ASN D N   1 
ATOM   1919  C  CA  . ASN A 1 301 ? 108.684 118.487 172.792 1.00 89.79  ? 248 ASN D CA  1 
ATOM   1920  C  C   . ASN A 1 301 ? 109.095 119.948 172.672 1.00 90.72  ? 248 ASN D C   1 
ATOM   1921  O  O   . ASN A 1 301 ? 110.104 120.283 172.050 1.00 91.52  ? 248 ASN D O   1 
ATOM   1922  C  CB  . ASN A 1 301 ? 109.371 117.855 173.999 1.00 92.57  ? 248 ASN D CB  1 
ATOM   1923  C  CG  . ASN A 1 301 ? 108.924 116.434 174.244 1.00 98.68  ? 248 ASN D CG  1 
ATOM   1924  O  OD1 . ASN A 1 301 ? 108.220 115.842 173.428 1.00 97.63  ? 248 ASN D OD1 1 
ATOM   1925  N  ND2 . ASN A 1 301 ? 109.336 115.873 175.373 1.00 100.54 ? 248 ASN D ND2 1 
ATOM   1926  N  N   . ARG A 1 302 ? 108.297 120.826 173.281 1.00 89.49  ? 249 ARG D N   1 
ATOM   1927  C  CA  . ARG A 1 302 ? 108.651 122.239 173.303 1.00 90.70  ? 249 ARG D CA  1 
ATOM   1928  C  C   . ARG A 1 302 ? 109.935 122.488 174.078 1.00 90.88  ? 249 ARG D C   1 
ATOM   1929  O  O   . ARG A 1 302 ? 110.593 123.510 173.859 1.00 86.97  ? 249 ARG D O   1 
ATOM   1930  C  CB  . ARG A 1 302 ? 107.515 123.059 173.910 1.00 89.68  ? 249 ARG D CB  1 
ATOM   1931  C  CG  . ARG A 1 302 ? 106.158 122.770 173.313 1.00 89.39  ? 249 ARG D CG  1 
ATOM   1932  C  CD  . ARG A 1 302 ? 105.063 123.409 174.139 1.00 89.31  ? 249 ARG D CD  1 
ATOM   1933  N  NE  . ARG A 1 302 ? 103.793 122.716 173.967 1.00 93.46  ? 249 ARG D NE  1 
ATOM   1934  C  CZ  . ARG A 1 302 ? 103.439 121.629 174.637 1.00 95.06  ? 249 ARG D CZ  1 
ATOM   1935  N  NH1 . ARG A 1 302 ? 104.237 121.082 175.539 1.00 92.46  ? 249 ARG D NH1 1 
ATOM   1936  N  NH2 . ARG A 1 302 ? 102.256 121.073 174.393 1.00 93.00  ? 249 ARG D NH2 1 
ATOM   1937  N  N   . GLU A 1 303 ? 110.297 121.581 174.987 1.00 94.86  ? 250 GLU D N   1 
ATOM   1938  C  CA  . GLU A 1 303 ? 111.541 121.724 175.732 1.00 92.06  ? 250 GLU D CA  1 
ATOM   1939  C  C   . GLU A 1 303 ? 112.750 121.605 174.816 1.00 88.81  ? 250 GLU D C   1 
ATOM   1940  O  O   . GLU A 1 303 ? 113.723 122.353 174.964 1.00 92.88  ? 250 GLU D O   1 
ATOM   1941  C  CB  . GLU A 1 303 ? 111.601 120.677 176.842 1.00 96.33  ? 250 GLU D CB  1 
ATOM   1942  C  CG  . GLU A 1 303 ? 110.356 120.644 177.712 1.00 104.97 ? 250 GLU D CG  1 
ATOM   1943  C  CD  . GLU A 1 303 ? 110.239 119.370 178.531 1.00 115.25 ? 250 GLU D CD  1 
ATOM   1944  O  OE1 . GLU A 1 303 ? 111.272 118.712 178.775 1.00 115.79 ? 250 GLU D OE1 1 
ATOM   1945  O  OE2 . GLU A 1 303 ? 109.107 119.025 178.927 1.00 118.71 ? 250 GLU D OE2 1 
ATOM   1946  N  N   . SER A 1 304 ? 112.704 120.682 173.856 1.00 85.02  ? 251 SER D N   1 
ATOM   1947  C  CA  . SER A 1 304 ? 113.828 120.442 172.953 1.00 81.86  ? 251 SER D CA  1 
ATOM   1948  C  C   . SER A 1 304 ? 113.878 121.544 171.894 1.00 75.57  ? 251 SER D C   1 
ATOM   1949  O  O   . SER A 1 304 ? 113.568 121.348 170.719 1.00 72.89  ? 251 SER D O   1 
ATOM   1950  C  CB  . SER A 1 304 ? 113.718 119.063 172.321 1.00 80.79  ? 251 SER D CB  1 
ATOM   1951  O  OG  . SER A 1 304 ? 114.860 118.783 171.531 1.00 77.42  ? 251 SER D OG  1 
ATOM   1952  N  N   . VAL A 1 305 ? 114.269 122.738 172.347 1.00 72.56  ? 252 VAL D N   1 
ATOM   1953  C  CA  . VAL A 1 305 ? 114.441 123.860 171.421 1.00 67.13  ? 252 VAL D CA  1 
ATOM   1954  C  C   . VAL A 1 305 ? 115.537 123.604 170.396 1.00 64.97  ? 252 VAL D C   1 
ATOM   1955  O  O   . VAL A 1 305 ? 115.333 123.931 169.218 1.00 66.24  ? 252 VAL D O   1 
ATOM   1956  C  CB  . VAL A 1 305 ? 114.644 125.165 172.203 1.00 66.93  ? 252 VAL D CB  1 
ATOM   1957  C  CG1 . VAL A 1 305 ? 114.627 126.353 171.259 1.00 64.88  ? 252 VAL D CG1 1 
ATOM   1958  C  CG2 . VAL A 1 305 ? 113.575 125.315 173.262 1.00 67.54  ? 252 VAL D CG2 1 
ATOM   1959  N  N   . PRO A 1 306 ? 116.719 123.078 170.752 1.00 64.04  ? 253 PRO D N   1 
ATOM   1960  C  CA  . PRO A 1 306 ? 117.755 122.886 169.722 1.00 64.57  ? 253 PRO D CA  1 
ATOM   1961  C  C   . PRO A 1 306 ? 117.334 121.990 168.571 1.00 64.95  ? 253 PRO D C   1 
ATOM   1962  O  O   . PRO A 1 306 ? 117.660 122.286 167.415 1.00 63.16  ? 253 PRO D O   1 
ATOM   1963  C  CB  . PRO A 1 306 ? 118.915 122.273 170.514 1.00 63.25  ? 253 PRO D CB  1 
ATOM   1964  C  CG  . PRO A 1 306 ? 118.717 122.752 171.884 1.00 64.68  ? 253 PRO D CG  1 
ATOM   1965  C  CD  . PRO A 1 306 ? 117.244 122.768 172.093 1.00 65.37  ? 253 PRO D CD  1 
ATOM   1966  N  N   . ALA A 1 307 ? 116.600 120.911 168.846 1.00 64.88  ? 254 ALA D N   1 
ATOM   1967  C  CA  . ALA A 1 307 ? 116.192 120.005 167.778 1.00 59.70  ? 254 ALA D CA  1 
ATOM   1968  C  C   . ALA A 1 307 ? 115.209 120.679 166.829 1.00 61.94  ? 254 ALA D C   1 
ATOM   1969  O  O   . ALA A 1 307 ? 115.351 120.592 165.603 1.00 62.99  ? 254 ALA D O   1 
ATOM   1970  C  CB  . ALA A 1 307 ? 115.585 118.738 168.373 1.00 55.36  ? 254 ALA D CB  1 
ATOM   1971  N  N   . ARG A 1 308 ? 114.204 121.360 167.379 1.00 60.54  ? 255 ARG D N   1 
ATOM   1972  C  CA  . ARG A 1 308 ? 113.228 122.037 166.537 1.00 59.86  ? 255 ARG D CA  1 
ATOM   1973  C  C   . ARG A 1 308 ? 113.877 123.157 165.738 1.00 59.53  ? 255 ARG D C   1 
ATOM   1974  O  O   . ARG A 1 308 ? 113.527 123.380 164.574 1.00 62.59  ? 255 ARG D O   1 
ATOM   1975  C  CB  . ARG A 1 308 ? 112.082 122.576 167.390 1.00 64.15  ? 255 ARG D CB  1 
ATOM   1976  C  CG  . ARG A 1 308 ? 111.466 121.543 168.313 1.00 65.61  ? 255 ARG D CG  1 
ATOM   1977  C  CD  . ARG A 1 308 ? 109.968 121.446 168.123 1.00 68.72  ? 255 ARG D CD  1 
ATOM   1978  N  NE  . ARG A 1 308 ? 109.268 122.664 168.506 1.00 72.62  ? 255 ARG D NE  1 
ATOM   1979  C  CZ  . ARG A 1 308 ? 107.994 122.906 168.232 1.00 73.24  ? 255 ARG D CZ  1 
ATOM   1980  N  NH1 . ARG A 1 308 ? 107.260 122.048 167.547 1.00 72.59  ? 255 ARG D NH1 1 
ATOM   1981  N  NH2 . ARG A 1 308 ? 107.443 124.039 168.655 1.00 73.49  ? 255 ARG D NH2 1 
ATOM   1982  N  N   . THR A 1 309 ? 114.816 123.881 166.348 1.00 58.01  ? 256 THR D N   1 
ATOM   1983  C  CA  . THR A 1 309 ? 115.533 124.922 165.620 1.00 55.71  ? 256 THR D CA  1 
ATOM   1984  C  C   . THR A 1 309 ? 116.339 124.333 164.473 1.00 55.38  ? 256 THR D C   1 
ATOM   1985  O  O   . THR A 1 309 ? 116.333 124.872 163.357 1.00 56.71  ? 256 THR D O   1 
ATOM   1986  C  CB  . THR A 1 309 ? 116.442 125.691 166.573 1.00 57.59  ? 256 THR D CB  1 
ATOM   1987  O  OG1 . THR A 1 309 ? 115.647 126.320 167.584 1.00 66.44  ? 256 THR D OG1 1 
ATOM   1988  C  CG2 . THR A 1 309 ? 117.220 126.751 165.825 1.00 54.16  ? 256 THR D CG2 1 
ATOM   1989  N  N   . VAL A 1 310 ? 117.030 123.220 164.723 1.00 55.91  ? 257 VAL D N   1 
ATOM   1990  C  CA  . VAL A 1 310 ? 117.776 122.550 163.662 1.00 56.79  ? 257 VAL D CA  1 
ATOM   1991  C  C   . VAL A 1 310 ? 116.843 122.190 162.517 1.00 55.69  ? 257 VAL D C   1 
ATOM   1992  O  O   . VAL A 1 310 ? 117.116 122.500 161.351 1.00 53.49  ? 257 VAL D O   1 
ATOM   1993  C  CB  . VAL A 1 310 ? 118.494 121.306 164.214 1.00 53.84  ? 257 VAL D CB  1 
ATOM   1994  C  CG1 . VAL A 1 310 ? 118.777 120.319 163.100 1.00 48.02  ? 257 VAL D CG1 1 
ATOM   1995  C  CG2 . VAL A 1 310 ? 119.780 121.705 164.908 1.00 56.85  ? 257 VAL D CG2 1 
ATOM   1996  N  N   . PHE A 1 311 ? 115.711 121.560 162.839 1.00 55.10  ? 258 PHE D N   1 
ATOM   1997  C  CA  . PHE A 1 311 ? 114.765 121.157 161.803 1.00 50.93  ? 258 PHE D CA  1 
ATOM   1998  C  C   . PHE A 1 311 ? 114.281 122.353 160.995 1.00 49.73  ? 258 PHE D C   1 
ATOM   1999  O  O   . PHE A 1 311 ? 114.340 122.346 159.760 1.00 50.39  ? 258 PHE D O   1 
ATOM   2000  C  CB  . PHE A 1 311 ? 113.579 120.428 162.429 1.00 52.40  ? 258 PHE D CB  1 
ATOM   2001  C  CG  . PHE A 1 311 ? 113.793 118.960 162.589 1.00 57.05  ? 258 PHE D CG  1 
ATOM   2002  C  CD1 . PHE A 1 311 ? 113.708 118.118 161.504 1.00 58.35  ? 258 PHE D CD1 1 
ATOM   2003  C  CD2 . PHE A 1 311 ? 114.073 118.419 163.824 1.00 58.94  ? 258 PHE D CD2 1 
ATOM   2004  C  CE1 . PHE A 1 311 ? 113.905 116.765 161.647 1.00 57.84  ? 258 PHE D CE1 1 
ATOM   2005  C  CE2 . PHE A 1 311 ? 114.273 117.070 163.972 1.00 54.86  ? 258 PHE D CE2 1 
ATOM   2006  C  CZ  . PHE A 1 311 ? 114.188 116.241 162.882 1.00 55.24  ? 258 PHE D CZ  1 
ATOM   2007  N  N   . GLY A 1 312 ? 113.808 123.396 161.677 1.00 49.22  ? 259 GLY D N   1 
ATOM   2008  C  CA  . GLY A 1 312 ? 113.226 124.523 160.970 1.00 44.20  ? 259 GLY D CA  1 
ATOM   2009  C  C   . GLY A 1 312 ? 114.222 125.237 160.078 1.00 47.49  ? 259 GLY D C   1 
ATOM   2010  O  O   . GLY A 1 312 ? 113.951 125.492 158.900 1.00 52.06  ? 259 GLY D O   1 
ATOM   2011  N  N   . VAL A 1 313 ? 115.400 125.550 160.618 1.00 46.00  ? 260 VAL D N   1 
ATOM   2012  C  CA  . VAL A 1 313 ? 116.370 126.304 159.834 1.00 43.28  ? 260 VAL D CA  1 
ATOM   2013  C  C   . VAL A 1 313 ? 116.920 125.454 158.694 1.00 44.07  ? 260 VAL D C   1 
ATOM   2014  O  O   . VAL A 1 313 ? 117.128 125.952 157.582 1.00 44.30  ? 260 VAL D O   1 
ATOM   2015  C  CB  . VAL A 1 313 ? 117.487 126.848 160.739 1.00 44.20  ? 260 VAL D CB  1 
ATOM   2016  C  CG1 . VAL A 1 313 ? 118.475 127.660 159.927 1.00 41.62  ? 260 VAL D CG1 1 
ATOM   2017  C  CG2 . VAL A 1 313 ? 116.891 127.702 161.837 1.00 43.39  ? 260 VAL D CG2 1 
ATOM   2018  N  N   . THR A 1 314 ? 117.164 124.164 158.939 1.00 43.53  ? 261 THR D N   1 
ATOM   2019  C  CA  . THR A 1 314 ? 117.670 123.306 157.875 1.00 44.08  ? 261 THR D CA  1 
ATOM   2020  C  C   . THR A 1 314 ? 116.659 123.169 156.746 1.00 44.48  ? 261 THR D C   1 
ATOM   2021  O  O   . THR A 1 314 ? 117.028 123.222 155.567 1.00 44.79  ? 261 THR D O   1 
ATOM   2022  C  CB  . THR A 1 314 ? 118.036 121.937 158.441 1.00 47.28  ? 261 THR D CB  1 
ATOM   2023  O  OG1 . THR A 1 314 ? 119.095 122.088 159.392 1.00 50.01  ? 261 THR D OG1 1 
ATOM   2024  C  CG2 . THR A 1 314 ? 118.488 121.000 157.335 1.00 45.23  ? 261 THR D CG2 1 
ATOM   2025  N  N   . THR A 1 315 ? 115.377 123.000 157.079 1.00 44.35  ? 262 THR D N   1 
ATOM   2026  C  CA  . THR A 1 315 ? 114.366 122.888 156.034 1.00 42.33  ? 262 THR D CA  1 
ATOM   2027  C  C   . THR A 1 315 ? 114.229 124.186 155.247 1.00 41.80  ? 262 THR D C   1 
ATOM   2028  O  O   . THR A 1 315 ? 114.076 124.157 154.021 1.00 42.49  ? 262 THR D O   1 
ATOM   2029  C  CB  . THR A 1 315 ? 113.026 122.478 156.633 1.00 40.46  ? 262 THR D CB  1 
ATOM   2030  O  OG1 . THR A 1 315 ? 112.686 123.374 157.696 1.00 45.75  ? 262 THR D OG1 1 
ATOM   2031  C  CG2 . THR A 1 315 ? 113.105 121.066 157.169 1.00 39.03  ? 262 THR D CG2 1 
ATOM   2032  N  N   . VAL A 1 316 ? 114.282 125.337 155.925 1.00 40.38  ? 263 VAL D N   1 
ATOM   2033  C  CA  . VAL A 1 316 ? 114.189 126.605 155.202 1.00 39.54  ? 263 VAL D CA  1 
ATOM   2034  C  C   . VAL A 1 316 ? 115.387 126.789 154.277 1.00 39.21  ? 263 VAL D C   1 
ATOM   2035  O  O   . VAL A 1 316 ? 115.242 127.236 153.133 1.00 40.22  ? 263 VAL D O   1 
ATOM   2036  C  CB  . VAL A 1 316 ? 114.048 127.782 156.181 1.00 38.97  ? 263 VAL D CB  1 
ATOM   2037  C  CG1 . VAL A 1 316 ? 114.125 129.091 155.435 1.00 35.40  ? 263 VAL D CG1 1 
ATOM   2038  C  CG2 . VAL A 1 316 ? 112.736 127.694 156.908 1.00 40.16  ? 263 VAL D CG2 1 
ATOM   2039  N  N   . LEU A 1 317 ? 116.587 126.462 154.756 1.00 39.04  ? 264 LEU D N   1 
ATOM   2040  C  CA  . LEU A 1 317 ? 117.774 126.588 153.917 1.00 38.51  ? 264 LEU D CA  1 
ATOM   2041  C  C   . LEU A 1 317 ? 117.704 125.661 152.710 1.00 40.52  ? 264 LEU D C   1 
ATOM   2042  O  O   . LEU A 1 317 ? 118.045 126.059 151.589 1.00 41.50  ? 264 LEU D O   1 
ATOM   2043  C  CB  . LEU A 1 317 ? 119.023 126.309 154.748 1.00 36.07  ? 264 LEU D CB  1 
ATOM   2044  C  CG  . LEU A 1 317 ? 120.360 126.243 154.020 1.00 36.85  ? 264 LEU D CG  1 
ATOM   2045  C  CD1 . LEU A 1 317 ? 120.628 127.520 153.263 1.00 34.76  ? 264 LEU D CD1 1 
ATOM   2046  C  CD2 . LEU A 1 317 ? 121.461 125.986 155.013 1.00 38.92  ? 264 LEU D CD2 1 
ATOM   2047  N  N   . THR A 1 318 ? 117.255 124.422 152.917 1.00 40.41  ? 265 THR D N   1 
ATOM   2048  C  CA  . THR A 1 318 ? 117.111 123.493 151.803 1.00 38.26  ? 265 THR D CA  1 
ATOM   2049  C  C   . THR A 1 318 ? 116.088 123.992 150.793 1.00 39.73  ? 265 THR D C   1 
ATOM   2050  O  O   . THR A 1 318 ? 116.310 123.901 149.583 1.00 41.10  ? 265 THR D O   1 
ATOM   2051  C  CB  . THR A 1 318 ? 116.721 122.112 152.320 1.00 38.17  ? 265 THR D CB  1 
ATOM   2052  O  OG1 . THR A 1 318 ? 117.791 121.581 153.108 1.00 46.37  ? 265 THR D OG1 1 
ATOM   2053  C  CG2 . THR A 1 318 ? 116.443 121.174 151.171 1.00 35.33  ? 265 THR D CG2 1 
ATOM   2054  N  N   . MET A 1 319 ? 114.959 124.521 151.267 1.00 39.29  ? 266 MET D N   1 
ATOM   2055  C  CA  . MET A 1 319 ? 113.943 125.032 150.352 1.00 35.09  ? 266 MET D CA  1 
ATOM   2056  C  C   . MET A 1 319 ? 114.456 126.222 149.558 1.00 35.09  ? 266 MET D C   1 
ATOM   2057  O  O   . MET A 1 319 ? 114.185 126.338 148.359 1.00 37.02  ? 266 MET D O   1 
ATOM   2058  C  CB  . MET A 1 319 ? 112.684 125.413 151.125 1.00 38.40  ? 266 MET D CB  1 
ATOM   2059  C  CG  . MET A 1 319 ? 111.674 124.296 151.271 1.00 44.01  ? 266 MET D CG  1 
ATOM   2060  S  SD  . MET A 1 319 ? 110.740 123.992 149.768 1.00 50.86  ? 266 MET D SD  1 
ATOM   2061  C  CE  . MET A 1 319 ? 111.640 122.610 149.105 1.00 43.74  ? 266 MET D CE  1 
ATOM   2062  N  N   . THR A 1 320 ? 115.192 127.123 150.211 1.00 36.56  ? 267 THR D N   1 
ATOM   2063  C  CA  . THR A 1 320 ? 115.758 128.267 149.505 1.00 34.54  ? 267 THR D CA  1 
ATOM   2064  C  C   . THR A 1 320 ? 116.737 127.818 148.432 1.00 35.83  ? 267 THR D C   1 
ATOM   2065  O  O   . THR A 1 320 ? 116.681 128.293 147.290 1.00 39.09  ? 267 THR D O   1 
ATOM   2066  C  CB  . THR A 1 320 ? 116.453 129.199 150.494 1.00 32.67  ? 267 THR D CB  1 
ATOM   2067  O  OG1 . THR A 1 320 ? 115.485 129.745 151.395 1.00 39.39  ? 267 THR D OG1 1 
ATOM   2068  C  CG2 . THR A 1 320 ? 117.141 130.326 149.764 1.00 28.30  ? 267 THR D CG2 1 
ATOM   2069  N  N   . THR A 1 321 ? 117.627 126.890 148.780 1.00 34.84  ? 268 THR D N   1 
ATOM   2070  C  CA  . THR A 1 321 ? 118.597 126.385 147.817 1.00 34.95  ? 268 THR D CA  1 
ATOM   2071  C  C   . THR A 1 321 ? 117.911 125.679 146.655 1.00 37.39  ? 268 THR D C   1 
ATOM   2072  O  O   . THR A 1 321 ? 118.309 125.846 145.500 1.00 38.45  ? 268 THR D O   1 
ATOM   2073  C  CB  . THR A 1 321 ? 119.573 125.452 148.526 1.00 38.54  ? 268 THR D CB  1 
ATOM   2074  O  OG1 . THR A 1 321 ? 120.485 126.231 149.307 1.00 38.84  ? 268 THR D OG1 1 
ATOM   2075  C  CG2 . THR A 1 321 ? 120.346 124.613 147.532 1.00 44.48  ? 268 THR D CG2 1 
ATOM   2076  N  N   . LEU A 1 322 ? 116.878 124.890 146.939 1.00 38.22  ? 269 LEU D N   1 
ATOM   2077  C  CA  . LEU A 1 322 ? 116.166 124.194 145.876 1.00 35.71  ? 269 LEU D CA  1 
ATOM   2078  C  C   . LEU A 1 322 ? 115.467 125.173 144.947 1.00 37.91  ? 269 LEU D C   1 
ATOM   2079  O  O   . LEU A 1 322 ? 115.498 125.006 143.725 1.00 42.56  ? 269 LEU D O   1 
ATOM   2080  C  CB  . LEU A 1 322 ? 115.158 123.220 146.476 1.00 38.37  ? 269 LEU D CB  1 
ATOM   2081  C  CG  . LEU A 1 322 ? 115.320 121.746 146.137 1.00 42.57  ? 269 LEU D CG  1 
ATOM   2082  C  CD1 . LEU A 1 322 ? 116.768 121.343 146.267 1.00 45.15  ? 269 LEU D CD1 1 
ATOM   2083  C  CD2 . LEU A 1 322 ? 114.463 120.927 147.061 1.00 41.50  ? 269 LEU D CD2 1 
ATOM   2084  N  N   . SER A 1 323 ? 114.824 126.197 145.505 1.00 37.39  ? 270 SER D N   1 
ATOM   2085  C  CA  . SER A 1 323 ? 114.118 127.161 144.671 1.00 35.58  ? 270 SER D CA  1 
ATOM   2086  C  C   . SER A 1 323 ? 115.092 127.937 143.796 1.00 38.72  ? 270 SER D C   1 
ATOM   2087  O  O   . SER A 1 323 ? 114.807 128.220 142.629 1.00 43.29  ? 270 SER D O   1 
ATOM   2088  C  CB  . SER A 1 323 ? 113.294 128.105 145.541 1.00 34.44  ? 270 SER D CB  1 
ATOM   2089  O  OG  . SER A 1 323 ? 114.127 128.924 146.331 1.00 41.77  ? 270 SER D OG  1 
ATOM   2090  N  N   . ILE A 1 324 ? 116.251 128.301 144.347 1.00 38.41  ? 271 ILE D N   1 
ATOM   2091  C  CA  . ILE A 1 324 ? 117.218 129.068 143.566 1.00 36.68  ? 271 ILE D CA  1 
ATOM   2092  C  C   . ILE A 1 324 ? 117.867 128.202 142.493 1.00 40.50  ? 271 ILE D C   1 
ATOM   2093  O  O   . ILE A 1 324 ? 118.003 128.621 141.338 1.00 47.99  ? 271 ILE D O   1 
ATOM   2094  C  CB  . ILE A 1 324 ? 118.267 129.708 144.491 1.00 33.97  ? 271 ILE D CB  1 
ATOM   2095  C  CG1 . ILE A 1 324 ? 117.660 130.896 145.230 1.00 33.10  ? 271 ILE D CG1 1 
ATOM   2096  C  CG2 . ILE A 1 324 ? 119.473 130.159 143.700 1.00 33.97  ? 271 ILE D CG2 1 
ATOM   2097  C  CD1 . ILE A 1 324 ? 118.595 131.533 146.203 1.00 31.88  ? 271 ILE D CD1 1 
ATOM   2098  N  N   . SER A 1 325 ? 118.280 126.984 142.849 1.00 39.87  ? 272 SER D N   1 
ATOM   2099  C  CA  . SER A 1 325 ? 119.081 126.180 141.932 1.00 39.54  ? 272 SER D CA  1 
ATOM   2100  C  C   . SER A 1 325 ? 118.233 125.557 140.833 1.00 45.29  ? 272 SER D C   1 
ATOM   2101  O  O   . SER A 1 325 ? 118.741 125.258 139.748 1.00 48.50  ? 272 SER D O   1 
ATOM   2102  C  CB  . SER A 1 325 ? 119.826 125.091 142.697 1.00 44.36  ? 272 SER D CB  1 
ATOM   2103  O  OG  . SER A 1 325 ? 119.098 123.877 142.673 1.00 48.20  ? 272 SER D OG  1 
ATOM   2104  N  N   . ALA A 1 326 ? 116.946 125.329 141.095 1.00 48.40  ? 273 ALA D N   1 
ATOM   2105  C  CA  . ALA A 1 326 ? 116.080 124.768 140.066 1.00 50.55  ? 273 ALA D CA  1 
ATOM   2106  C  C   . ALA A 1 326 ? 115.819 125.755 138.942 1.00 53.47  ? 273 ALA D C   1 
ATOM   2107  O  O   . ALA A 1 326 ? 115.261 125.372 137.911 1.00 59.20  ? 273 ALA D O   1 
ATOM   2108  C  CB  . ALA A 1 326 ? 114.756 124.310 140.673 1.00 45.78  ? 273 ALA D CB  1 
ATOM   2109  N  N   . ARG A 1 327 ? 116.205 127.017 139.122 1.00 53.47  ? 274 ARG D N   1 
ATOM   2110  C  CA  . ARG A 1 327 ? 116.012 128.014 138.078 1.00 54.79  ? 274 ARG D CA  1 
ATOM   2111  C  C   . ARG A 1 327 ? 116.799 127.664 136.824 1.00 56.78  ? 274 ARG D C   1 
ATOM   2112  O  O   . ARG A 1 327 ? 116.305 127.833 135.704 1.00 60.06  ? 274 ARG D O   1 
ATOM   2113  C  CB  . ARG A 1 327 ? 116.421 129.387 138.600 1.00 53.98  ? 274 ARG D CB  1 
ATOM   2114  C  CG  . ARG A 1 327 ? 116.458 130.459 137.548 1.00 58.19  ? 274 ARG D CG  1 
ATOM   2115  C  CD  . ARG A 1 327 ? 115.157 131.227 137.479 1.00 63.96  ? 274 ARG D CD  1 
ATOM   2116  N  NE  . ARG A 1 327 ? 114.031 130.435 136.998 1.00 62.95  ? 274 ARG D NE  1 
ATOM   2117  C  CZ  . ARG A 1 327 ? 113.014 130.043 137.753 1.00 59.31  ? 274 ARG D CZ  1 
ATOM   2118  N  NH1 . ARG A 1 327 ? 112.963 130.318 139.044 1.00 57.10  ? 274 ARG D NH1 1 
ATOM   2119  N  NH2 . ARG A 1 327 ? 112.019 129.363 137.196 1.00 56.19  ? 274 ARG D NH2 1 
ATOM   2120  N  N   . ASN A 1 328 ? 118.029 127.178 136.989 1.00 55.87  ? 275 ASN D N   1 
ATOM   2121  C  CA  . ASN A 1 328 ? 118.854 126.852 135.831 1.00 61.11  ? 275 ASN D CA  1 
ATOM   2122  C  C   . ASN A 1 328 ? 118.273 125.687 135.038 1.00 60.01  ? 275 ASN D C   1 
ATOM   2123  O  O   . ASN A 1 328 ? 118.359 125.662 133.806 1.00 58.49  ? 275 ASN D O   1 
ATOM   2124  C  CB  . ASN A 1 328 ? 120.279 126.544 136.280 1.00 64.79  ? 275 ASN D CB  1 
ATOM   2125  C  CG  . ASN A 1 328 ? 120.925 127.713 136.989 1.00 69.68  ? 275 ASN D CG  1 
ATOM   2126  O  OD1 . ASN A 1 328 ? 120.243 128.564 137.558 1.00 65.36  ? 275 ASN D OD1 1 
ATOM   2127  N  ND2 . ASN A 1 328 ? 122.250 127.763 136.958 1.00 73.77  ? 275 ASN D ND2 1 
ATOM   2128  N  N   . SER A 1 329 ? 117.700 124.702 135.725 1.00 60.77  ? 276 SER D N   1 
ATOM   2129  C  CA  . SER A 1 329 ? 117.066 123.591 135.024 1.00 63.90  ? 276 SER D CA  1 
ATOM   2130  C  C   . SER A 1 329 ? 115.827 124.046 134.262 1.00 62.95  ? 276 SER D C   1 
ATOM   2131  O  O   . SER A 1 329 ? 115.600 123.619 133.126 1.00 63.81  ? 276 SER D O   1 
ATOM   2132  C  CB  . SER A 1 329 ? 116.703 122.487 136.014 1.00 65.49  ? 276 SER D CB  1 
ATOM   2133  O  OG  . SER A 1 329 ? 115.898 121.502 135.394 1.00 68.70  ? 276 SER D OG  1 
ATOM   2134  N  N   . LEU A 1 330 ? 115.022 124.912 134.869 1.00 58.72  ? 277 LEU D N   1 
ATOM   2135  C  CA  . LEU A 1 330 ? 113.757 125.310 134.277 1.00 52.18  ? 277 LEU D CA  1 
ATOM   2136  C  C   . LEU A 1 330 ? 113.988 126.112 132.997 1.00 54.56  ? 277 LEU D C   1 
ATOM   2137  O  O   . LEU A 1 330 ? 115.019 126.772 132.845 1.00 56.63  ? 277 LEU D O   1 
ATOM   2138  C  CB  . LEU A 1 330 ? 112.948 126.135 135.274 1.00 51.62  ? 277 LEU D CB  1 
ATOM   2139  C  CG  . LEU A 1 330 ? 112.157 125.359 136.326 1.00 53.30  ? 277 LEU D CG  1 
ATOM   2140  C  CD1 . LEU A 1 330 ? 112.121 126.113 137.630 1.00 55.92  ? 277 LEU D CD1 1 
ATOM   2141  C  CD2 . LEU A 1 330 ? 110.750 125.129 135.840 1.00 53.63  ? 277 LEU D CD2 1 
ATOM   2142  N  N   . PRO A 1 331 ? 113.053 126.055 132.051 1.00 53.92  ? 278 PRO D N   1 
ATOM   2143  C  CA  . PRO A 1 331 ? 113.183 126.868 130.840 1.00 51.91  ? 278 PRO D CA  1 
ATOM   2144  C  C   . PRO A 1 331 ? 113.050 128.348 131.151 1.00 46.94  ? 278 PRO D C   1 
ATOM   2145  O  O   . PRO A 1 331 ? 112.409 128.749 132.123 1.00 49.26  ? 278 PRO D O   1 
ATOM   2146  C  CB  . PRO A 1 331 ? 112.031 126.377 129.961 1.00 51.74  ? 278 PRO D CB  1 
ATOM   2147  C  CG  . PRO A 1 331 ? 111.038 125.851 130.922 1.00 47.88  ? 278 PRO D CG  1 
ATOM   2148  C  CD  . PRO A 1 331 ? 111.833 125.234 132.025 1.00 51.49  ? 278 PRO D CD  1 
ATOM   2149  N  N   . LYS A 1 332 ? 113.673 129.164 130.307 1.00 43.07  ? 279 LYS D N   1 
ATOM   2150  C  CA  . LYS A 1 332 ? 113.729 130.608 130.518 1.00 45.45  ? 279 LYS D CA  1 
ATOM   2151  C  C   . LYS A 1 332 ? 112.528 131.243 129.833 1.00 43.62  ? 279 LYS D C   1 
ATOM   2152  O  O   . LYS A 1 332 ? 112.551 131.502 128.630 1.00 46.91  ? 279 LYS D O   1 
ATOM   2153  C  CB  . LYS A 1 332 ? 115.042 131.171 129.993 1.00 49.19  ? 279 LYS D CB  1 
ATOM   2154  C  CG  . LYS A 1 332 ? 116.268 130.482 130.564 1.00 53.02  ? 279 LYS D CG  1 
ATOM   2155  C  CD  . LYS A 1 332 ? 117.533 130.916 129.857 1.00 61.14  ? 279 LYS D CD  1 
ATOM   2156  C  CE  . LYS A 1 332 ? 118.742 130.192 130.421 1.00 63.59  ? 279 LYS D CE  1 
ATOM   2157  N  NZ  . LYS A 1 332 ? 119.940 130.357 129.552 1.00 66.13  ? 279 LYS D NZ  1 
ATOM   2158  N  N   . VAL A 1 333 ? 111.477 131.502 130.608 1.00 40.77  ? 280 VAL D N   1 
ATOM   2159  C  CA  . VAL A 1 333 ? 110.232 132.058 130.106 1.00 37.67  ? 280 VAL D CA  1 
ATOM   2160  C  C   . VAL A 1 333 ? 109.829 133.234 130.986 1.00 36.74  ? 280 VAL D C   1 
ATOM   2161  O  O   . VAL A 1 333 ? 110.376 133.448 132.065 1.00 40.07  ? 280 VAL D O   1 
ATOM   2162  C  CB  . VAL A 1 333 ? 109.107 131.007 130.057 1.00 38.85  ? 280 VAL D CB  1 
ATOM   2163  C  CG1 . VAL A 1 333 ? 109.290 130.100 128.869 1.00 40.89  ? 280 VAL D CG1 1 
ATOM   2164  C  CG2 . VAL A 1 333 ? 109.099 130.194 131.329 1.00 41.30  ? 280 VAL D CG2 1 
ATOM   2165  N  N   . ALA A 1 334 ? 108.863 134.006 130.499 1.00 34.59  ? 281 ALA D N   1 
ATOM   2166  C  CA  . ALA A 1 334 ? 108.362 135.181 131.199 1.00 29.43  ? 281 ALA D CA  1 
ATOM   2167  C  C   . ALA A 1 334 ? 107.123 134.901 132.040 1.00 33.27  ? 281 ALA D C   1 
ATOM   2168  O  O   . ALA A 1 334 ? 106.557 135.837 132.607 1.00 36.47  ? 281 ALA D O   1 
ATOM   2169  C  CB  . ALA A 1 334 ? 108.053 136.298 130.200 1.00 27.03  ? 281 ALA D CB  1 
ATOM   2170  N  N   . TYR A 1 335 ? 106.681 133.656 132.121 1.00 36.27  ? 282 TYR D N   1 
ATOM   2171  C  CA  . TYR A 1 335 ? 105.551 133.262 132.947 1.00 33.24  ? 282 TYR D CA  1 
ATOM   2172  C  C   . TYR A 1 335 ? 106.002 132.185 133.925 1.00 36.65  ? 282 TYR D C   1 
ATOM   2173  O  O   . TYR A 1 335 ? 107.151 131.746 133.912 1.00 38.99  ? 282 TYR D O   1 
ATOM   2174  C  CB  . TYR A 1 335 ? 104.384 132.774 132.086 1.00 32.79  ? 282 TYR D CB  1 
ATOM   2175  C  CG  . TYR A 1 335 ? 104.801 131.888 130.947 1.00 36.29  ? 282 TYR D CG  1 
ATOM   2176  C  CD1 . TYR A 1 335 ? 105.008 130.536 131.136 1.00 40.14  ? 282 TYR D CD1 1 
ATOM   2177  C  CD2 . TYR A 1 335 ? 104.990 132.404 129.680 1.00 39.69  ? 282 TYR D CD2 1 
ATOM   2178  C  CE1 . TYR A 1 335 ? 105.394 129.728 130.100 1.00 43.60  ? 282 TYR D CE1 1 
ATOM   2179  C  CE2 . TYR A 1 335 ? 105.374 131.600 128.638 1.00 43.14  ? 282 TYR D CE2 1 
ATOM   2180  C  CZ  . TYR A 1 335 ? 105.569 130.264 128.853 1.00 45.09  ? 282 TYR D CZ  1 
ATOM   2181  O  OH  . TYR A 1 335 ? 105.953 129.463 127.809 1.00 49.31  ? 282 TYR D OH  1 
ATOM   2182  N  N   . ALA A 1 336 ? 105.083 131.760 134.782 1.00 35.52  ? 283 ALA D N   1 
ATOM   2183  C  CA  . ALA A 1 336 ? 105.369 130.758 135.797 1.00 36.47  ? 283 ALA D CA  1 
ATOM   2184  C  C   . ALA A 1 336 ? 104.851 129.403 135.342 1.00 41.01  ? 283 ALA D C   1 
ATOM   2185  O  O   . ALA A 1 336 ? 103.701 129.286 134.910 1.00 41.13  ? 283 ALA D O   1 
ATOM   2186  C  CB  . ALA A 1 336 ? 104.739 131.142 137.135 1.00 34.20  ? 283 ALA D CB  1 
ATOM   2187  N  N   . THR A 1 337 ? 105.700 128.387 135.444 1.00 40.55  ? 284 THR D N   1 
ATOM   2188  C  CA  . THR A 1 337 ? 105.350 127.031 135.063 1.00 38.17  ? 284 THR D CA  1 
ATOM   2189  C  C   . THR A 1 337 ? 104.711 126.307 136.245 1.00 39.25  ? 284 THR D C   1 
ATOM   2190  O  O   . THR A 1 337 ? 104.603 126.843 137.347 1.00 45.38  ? 284 THR D O   1 
ATOM   2191  C  CB  . THR A 1 337 ? 106.585 126.296 134.555 1.00 40.03  ? 284 THR D CB  1 
ATOM   2192  O  OG1 . THR A 1 337 ? 107.571 126.252 135.588 1.00 44.07  ? 284 THR D OG1 1 
ATOM   2193  C  CG2 . THR A 1 337 ? 107.169 127.021 133.369 1.00 40.76  ? 284 THR D CG2 1 
ATOM   2194  N  N   . ALA A 1 338 ? 104.261 125.075 136.012 1.00 36.18  ? 285 ALA D N   1 
ATOM   2195  C  CA  . ALA A 1 338 ? 103.649 124.302 137.086 1.00 38.57  ? 285 ALA D CA  1 
ATOM   2196  C  C   . ALA A 1 338 ? 104.658 123.978 138.180 1.00 42.21  ? 285 ALA D C   1 
ATOM   2197  O  O   . ALA A 1 338 ? 104.326 124.009 139.374 1.00 46.32  ? 285 ALA D O   1 
ATOM   2198  C  CB  . ALA A 1 338 ? 103.034 123.026 136.523 1.00 40.17  ? 285 ALA D CB  1 
ATOM   2199  N  N   . MET A 1 339 ? 105.895 123.661 137.797 1.00 38.31  ? 286 MET D N   1 
ATOM   2200  C  CA  . MET A 1 339 ? 106.905 123.354 138.799 1.00 37.78  ? 286 MET D CA  1 
ATOM   2201  C  C   . MET A 1 339 ? 107.224 124.571 139.651 1.00 40.37  ? 286 MET D C   1 
ATOM   2202  O  O   . MET A 1 339 ? 107.550 124.427 140.833 1.00 45.08  ? 286 MET D O   1 
ATOM   2203  C  CB  . MET A 1 339 ? 108.166 122.815 138.131 1.00 35.96  ? 286 MET D CB  1 
ATOM   2204  C  CG  . MET A 1 339 ? 109.006 121.949 139.049 1.00 41.85  ? 286 MET D CG  1 
ATOM   2205  S  SD  . MET A 1 339 ? 110.145 120.862 138.184 1.00 57.88  ? 286 MET D SD  1 
ATOM   2206  C  CE  . MET A 1 339 ? 111.379 122.034 137.646 1.00 51.82  ? 286 MET D CE  1 
ATOM   2207  N  N   . ASP A 1 340 ? 107.121 125.771 139.080 1.00 37.89  ? 287 ASP D N   1 
ATOM   2208  C  CA  . ASP A 1 340 ? 107.277 126.979 139.878 1.00 36.46  ? 287 ASP D CA  1 
ATOM   2209  C  C   . ASP A 1 340 ? 106.211 127.067 140.957 1.00 37.73  ? 287 ASP D C   1 
ATOM   2210  O  O   . ASP A 1 340 ? 106.509 127.434 142.097 1.00 41.27  ? 287 ASP D O   1 
ATOM   2211  C  CB  . ASP A 1 340 ? 107.229 128.214 138.987 1.00 38.89  ? 287 ASP D CB  1 
ATOM   2212  C  CG  . ASP A 1 340 ? 108.421 128.312 138.079 1.00 49.01  ? 287 ASP D CG  1 
ATOM   2213  O  OD1 . ASP A 1 340 ? 109.267 127.401 138.124 1.00 52.23  ? 287 ASP D OD1 1 
ATOM   2214  O  OD2 . ASP A 1 340 ? 108.517 129.294 137.320 1.00 51.90  ? 287 ASP D OD2 1 
ATOM   2215  N  N   . TRP A 1 341 ? 104.962 126.747 140.618 1.00 35.67  ? 288 TRP D N   1 
ATOM   2216  C  CA  . TRP A 1 341 ? 103.911 126.772 141.627 1.00 35.40  ? 288 TRP D CA  1 
ATOM   2217  C  C   . TRP A 1 341 ? 104.153 125.724 142.700 1.00 38.13  ? 288 TRP D C   1 
ATOM   2218  O  O   . TRP A 1 341 ? 103.934 125.985 143.888 1.00 40.68  ? 288 TRP D O   1 
ATOM   2219  C  CB  . TRP A 1 341 ? 102.544 126.578 140.979 1.00 35.01  ? 288 TRP D CB  1 
ATOM   2220  C  CG  . TRP A 1 341 ? 102.159 127.699 140.084 1.00 37.55  ? 288 TRP D CG  1 
ATOM   2221  C  CD1 . TRP A 1 341 ? 101.860 127.621 138.763 1.00 41.17  ? 288 TRP D CD1 1 
ATOM   2222  C  CD2 . TRP A 1 341 ? 102.046 129.079 140.439 1.00 44.47  ? 288 TRP D CD2 1 
ATOM   2223  N  NE1 . TRP A 1 341 ? 101.564 128.862 138.268 1.00 43.49  ? 288 TRP D NE1 1 
ATOM   2224  C  CE2 . TRP A 1 341 ? 101.673 129.776 139.279 1.00 45.16  ? 288 TRP D CE2 1 
ATOM   2225  C  CE3 . TRP A 1 341 ? 102.226 129.793 141.625 1.00 44.39  ? 288 TRP D CE3 1 
ATOM   2226  C  CZ2 . TRP A 1 341 ? 101.473 131.149 139.270 1.00 48.24  ? 288 TRP D CZ2 1 
ATOM   2227  C  CZ3 . TRP A 1 341 ? 102.029 131.155 141.613 1.00 44.72  ? 288 TRP D CZ3 1 
ATOM   2228  C  CH2 . TRP A 1 341 ? 101.656 131.819 140.445 1.00 48.91  ? 288 TRP D CH2 1 
ATOM   2229  N  N   . PHE A 1 342 ? 104.610 124.535 142.310 1.00 36.62  ? 289 PHE D N   1 
ATOM   2230  C  CA  . PHE A 1 342 ? 104.896 123.518 143.317 1.00 35.91  ? 289 PHE D CA  1 
ATOM   2231  C  C   . PHE A 1 342 ? 105.990 123.981 144.269 1.00 36.73  ? 289 PHE D C   1 
ATOM   2232  O  O   . PHE A 1 342 ? 105.862 123.848 145.492 1.00 40.90  ? 289 PHE D O   1 
ATOM   2233  C  CB  . PHE A 1 342 ? 105.288 122.204 142.651 1.00 37.31  ? 289 PHE D CB  1 
ATOM   2234  C  CG  . PHE A 1 342 ? 105.260 121.029 143.582 1.00 39.84  ? 289 PHE D CG  1 
ATOM   2235  C  CD1 . PHE A 1 342 ? 104.081 120.361 143.831 1.00 39.45  ? 289 PHE D CD1 1 
ATOM   2236  C  CD2 . PHE A 1 342 ? 106.411 120.594 144.205 1.00 41.85  ? 289 PHE D CD2 1 
ATOM   2237  C  CE1 . PHE A 1 342 ? 104.049 119.287 144.680 1.00 40.92  ? 289 PHE D CE1 1 
ATOM   2238  C  CE2 . PHE A 1 342 ? 106.382 119.516 145.060 1.00 43.76  ? 289 PHE D CE2 1 
ATOM   2239  C  CZ  . PHE A 1 342 ? 105.199 118.864 145.294 1.00 43.08  ? 289 PHE D CZ  1 
ATOM   2240  N  N   . ILE A 1 343 ? 107.074 124.538 143.727 1.00 34.76  ? 290 ILE D N   1 
ATOM   2241  C  CA  . ILE A 1 343 ? 108.175 124.990 144.574 1.00 33.95  ? 290 ILE D CA  1 
ATOM   2242  C  C   . ILE A 1 343 ? 107.728 126.135 145.472 1.00 35.80  ? 290 ILE D C   1 
ATOM   2243  O  O   . ILE A 1 343 ? 108.092 126.194 146.651 1.00 39.43  ? 290 ILE D O   1 
ATOM   2244  C  CB  . ILE A 1 343 ? 109.389 125.384 143.716 1.00 31.26  ? 290 ILE D CB  1 
ATOM   2245  C  CG1 . ILE A 1 343 ? 109.893 124.184 142.923 1.00 34.79  ? 290 ILE D CG1 1 
ATOM   2246  C  CG2 . ILE A 1 343 ? 110.498 125.911 144.588 1.00 31.92  ? 290 ILE D CG2 1 
ATOM   2247  C  CD1 . ILE A 1 343 ? 111.079 124.502 142.059 1.00 37.51  ? 290 ILE D CD1 1 
ATOM   2248  N  N   . ALA A 1 344 ? 106.928 127.060 144.937 1.00 33.88  ? 291 ALA D N   1 
ATOM   2249  C  CA  . ALA A 1 344 ? 106.443 128.171 145.747 1.00 29.65  ? 291 ALA D CA  1 
ATOM   2250  C  C   . ALA A 1 344 ? 105.569 127.686 146.894 1.00 33.73  ? 291 ALA D C   1 
ATOM   2251  O  O   . ALA A 1 344 ? 105.706 128.159 148.027 1.00 39.29  ? 291 ALA D O   1 
ATOM   2252  C  CB  . ALA A 1 344 ? 105.674 129.159 144.878 1.00 29.63  ? 291 ALA D CB  1 
ATOM   2253  N  N   . VAL A 1 345 ? 104.671 126.737 146.628 1.00 33.91  ? 292 VAL D N   1 
ATOM   2254  C  CA  . VAL A 1 345 ? 103.791 126.253 147.686 1.00 35.06  ? 292 VAL D CA  1 
ATOM   2255  C  C   . VAL A 1 345 ? 104.579 125.470 148.732 1.00 37.65  ? 292 VAL D C   1 
ATOM   2256  O  O   . VAL A 1 345 ? 104.308 125.573 149.935 1.00 40.63  ? 292 VAL D O   1 
ATOM   2257  C  CB  . VAL A 1 345 ? 102.642 125.424 147.090 1.00 34.88  ? 292 VAL D CB  1 
ATOM   2258  C  CG1 . VAL A 1 345 ? 101.825 124.792 148.184 1.00 37.19  ? 292 VAL D CG1 1 
ATOM   2259  C  CG2 . VAL A 1 345 ? 101.758 126.307 146.242 1.00 33.98  ? 292 VAL D CG2 1 
ATOM   2260  N  N   . CYS A 1 346 ? 105.570 124.684 148.303 1.00 34.92  ? 293 CYS D N   1 
ATOM   2261  C  CA  . CYS A 1 346 ? 106.412 123.990 149.273 1.00 34.68  ? 293 CYS D CA  1 
ATOM   2262  C  C   . CYS A 1 346 ? 107.180 124.978 150.143 1.00 38.78  ? 293 CYS D C   1 
ATOM   2263  O  O   . CYS A 1 346 ? 107.306 124.783 151.360 1.00 44.78  ? 293 CYS D O   1 
ATOM   2264  C  CB  . CYS A 1 346 ? 107.374 123.046 148.559 1.00 34.47  ? 293 CYS D CB  1 
ATOM   2265  S  SG  . CYS A 1 346 ? 106.595 121.604 147.821 1.00 47.10  ? 293 CYS D SG  1 
ATOM   2266  N  N   . TYR A 1 347 ? 107.702 126.045 149.536 1.00 36.35  ? 294 TYR D N   1 
ATOM   2267  C  CA  . TYR A 1 347 ? 108.394 127.071 150.304 1.00 35.80  ? 294 TYR D CA  1 
ATOM   2268  C  C   . TYR A 1 347 ? 107.459 127.711 151.318 1.00 37.82  ? 294 TYR D C   1 
ATOM   2269  O  O   . TYR A 1 347 ? 107.848 127.958 152.465 1.00 41.78  ? 294 TYR D O   1 
ATOM   2270  C  CB  . TYR A 1 347 ? 108.968 128.125 149.361 1.00 32.59  ? 294 TYR D CB  1 
ATOM   2271  C  CG  . TYR A 1 347 ? 109.830 129.161 150.030 1.00 34.65  ? 294 TYR D CG  1 
ATOM   2272  C  CD1 . TYR A 1 347 ? 109.272 130.289 150.610 1.00 36.99  ? 294 TYR D CD1 1 
ATOM   2273  C  CD2 . TYR A 1 347 ? 111.205 129.024 150.063 1.00 36.15  ? 294 TYR D CD2 1 
ATOM   2274  C  CE1 . TYR A 1 347 ? 110.057 131.240 151.221 1.00 39.32  ? 294 TYR D CE1 1 
ATOM   2275  C  CE2 . TYR A 1 347 ? 111.997 129.970 150.669 1.00 41.33  ? 294 TYR D CE2 1 
ATOM   2276  C  CZ  . TYR A 1 347 ? 111.418 131.075 151.247 1.00 43.28  ? 294 TYR D CZ  1 
ATOM   2277  O  OH  . TYR A 1 347 ? 112.205 132.026 151.851 1.00 44.59  ? 294 TYR D OH  1 
ATOM   2278  N  N   . ALA A 1 348 ? 106.222 127.988 150.911 1.00 36.08  ? 295 ALA D N   1 
ATOM   2279  C  CA  . ALA A 1 348 ? 105.262 128.578 151.834 1.00 35.33  ? 295 ALA D CA  1 
ATOM   2280  C  C   . ALA A 1 348 ? 104.977 127.645 153.002 1.00 41.87  ? 295 ALA D C   1 
ATOM   2281  O  O   . ALA A 1 348 ? 104.904 128.090 154.151 1.00 48.16  ? 295 ALA D O   1 
ATOM   2282  C  CB  . ALA A 1 348 ? 103.972 128.932 151.100 1.00 30.97  ? 295 ALA D CB  1 
ATOM   2283  N  N   . PHE A 1 349 ? 104.821 126.347 152.732 1.00 40.65  ? 296 PHE D N   1 
ATOM   2284  C  CA  . PHE A 1 349 ? 104.566 125.398 153.813 1.00 40.24  ? 296 PHE D CA  1 
ATOM   2285  C  C   . PHE A 1 349 ? 105.730 125.345 154.796 1.00 41.85  ? 296 PHE D C   1 
ATOM   2286  O  O   . PHE A 1 349 ? 105.526 125.356 156.017 1.00 48.25  ? 296 PHE D O   1 
ATOM   2287  C  CB  . PHE A 1 349 ? 104.294 124.009 153.245 1.00 40.55  ? 296 PHE D CB  1 
ATOM   2288  C  CG  . PHE A 1 349 ? 102.850 123.742 152.963 1.00 42.84  ? 296 PHE D CG  1 
ATOM   2289  C  CD1 . PHE A 1 349 ? 102.252 124.220 151.817 1.00 42.38  ? 296 PHE D CD1 1 
ATOM   2290  C  CD2 . PHE A 1 349 ? 102.091 122.999 153.843 1.00 45.42  ? 296 PHE D CD2 1 
ATOM   2291  C  CE1 . PHE A 1 349 ? 100.925 123.971 151.559 1.00 45.57  ? 296 PHE D CE1 1 
ATOM   2292  C  CE2 . PHE A 1 349 ? 100.765 122.749 153.590 1.00 50.19  ? 296 PHE D CE2 1 
ATOM   2293  C  CZ  . PHE A 1 349 ? 100.182 123.232 152.447 1.00 49.27  ? 296 PHE D CZ  1 
ATOM   2294  N  N   . VAL A 1 350 ? 106.959 125.299 154.284 1.00 39.53  ? 297 VAL D N   1 
ATOM   2295  C  CA  . VAL A 1 350 ? 108.120 125.211 155.165 1.00 42.67  ? 297 VAL D CA  1 
ATOM   2296  C  C   . VAL A 1 350 ? 108.278 126.482 155.995 1.00 44.48  ? 297 VAL D C   1 
ATOM   2297  O  O   . VAL A 1 350 ? 108.546 126.427 157.206 1.00 44.47  ? 297 VAL D O   1 
ATOM   2298  C  CB  . VAL A 1 350 ? 109.379 124.901 154.340 1.00 40.61  ? 297 VAL D CB  1 
ATOM   2299  C  CG1 . VAL A 1 350 ? 110.606 125.012 155.197 1.00 41.86  ? 297 VAL D CG1 1 
ATOM   2300  C  CG2 . VAL A 1 350 ? 109.278 123.514 153.756 1.00 41.13  ? 297 VAL D CG2 1 
ATOM   2301  N  N   . PHE A 1 351 ? 108.115 127.647 155.370 1.00 42.79  ? 298 PHE D N   1 
ATOM   2302  C  CA  . PHE A 1 351 ? 108.267 128.891 156.114 1.00 40.42  ? 298 PHE D CA  1 
ATOM   2303  C  C   . PHE A 1 351 ? 107.155 129.059 157.139 1.00 47.22  ? 298 PHE D C   1 
ATOM   2304  O  O   . PHE A 1 351 ? 107.388 129.574 158.238 1.00 50.90  ? 298 PHE D O   1 
ATOM   2305  C  CB  . PHE A 1 351 ? 108.305 130.077 155.159 1.00 40.29  ? 298 PHE D CB  1 
ATOM   2306  C  CG  . PHE A 1 351 ? 109.313 131.114 155.536 1.00 47.22  ? 298 PHE D CG  1 
ATOM   2307  C  CD1 . PHE A 1 351 ? 108.998 132.106 156.443 1.00 49.28  ? 298 PHE D CD1 1 
ATOM   2308  C  CD2 . PHE A 1 351 ? 110.579 131.092 154.991 1.00 48.49  ? 298 PHE D CD2 1 
ATOM   2309  C  CE1 . PHE A 1 351 ? 109.926 133.056 156.794 1.00 49.49  ? 298 PHE D CE1 1 
ATOM   2310  C  CE2 . PHE A 1 351 ? 111.510 132.042 155.340 1.00 46.50  ? 298 PHE D CE2 1 
ATOM   2311  C  CZ  . PHE A 1 351 ? 111.184 133.022 156.242 1.00 49.90  ? 298 PHE D CZ  1 
ATOM   2312  N  N   . SER A 1 352 ? 105.939 128.626 156.801 1.00 48.70  ? 299 SER D N   1 
ATOM   2313  C  CA  . SER A 1 352 ? 104.848 128.676 157.762 1.00 50.28  ? 299 SER D CA  1 
ATOM   2314  C  C   . SER A 1 352 ? 105.123 127.769 158.951 1.00 50.76  ? 299 SER D C   1 
ATOM   2315  O  O   . SER A 1 352 ? 104.810 128.122 160.091 1.00 50.84  ? 299 SER D O   1 
ATOM   2316  C  CB  . SER A 1 352 ? 103.539 128.292 157.081 1.00 49.22  ? 299 SER D CB  1 
ATOM   2317  O  OG  . SER A 1 352 ? 102.444 128.456 157.958 1.00 65.98  ? 299 SER D OG  1 
ATOM   2318  N  N   . ALA A 1 353 ? 105.705 126.593 158.710 1.00 49.91  ? 300 ALA D N   1 
ATOM   2319  C  CA  . ALA A 1 353 ? 106.081 125.728 159.826 1.00 51.05  ? 300 ALA D CA  1 
ATOM   2320  C  C   . ALA A 1 353 ? 107.117 126.396 160.722 1.00 54.19  ? 300 ALA D C   1 
ATOM   2321  O  O   . ALA A 1 353 ? 107.023 126.331 161.956 1.00 57.71  ? 300 ALA D O   1 
ATOM   2322  C  CB  . ALA A 1 353 ? 106.608 124.397 159.301 1.00 50.61  ? 300 ALA D CB  1 
ATOM   2323  N  N   . LEU A 1 354 ? 108.116 127.044 160.120 1.00 52.51  ? 301 LEU D N   1 
ATOM   2324  C  CA  . LEU A 1 354 ? 109.119 127.740 160.923 1.00 48.02  ? 301 LEU D CA  1 
ATOM   2325  C  C   . LEU A 1 354 ? 108.490 128.849 161.762 1.00 51.03  ? 301 LEU D C   1 
ATOM   2326  O  O   . LEU A 1 354 ? 108.816 129.009 162.946 1.00 54.62  ? 301 LEU D O   1 
ATOM   2327  C  CB  . LEU A 1 354 ? 110.208 128.311 160.021 1.00 47.40  ? 301 LEU D CB  1 
ATOM   2328  C  CG  . LEU A 1 354 ? 111.310 129.076 160.746 1.00 47.91  ? 301 LEU D CG  1 
ATOM   2329  C  CD1 . LEU A 1 354 ? 112.199 128.129 161.514 1.00 50.15  ? 301 LEU D CD1 1 
ATOM   2330  C  CD2 . LEU A 1 354 ? 112.117 129.895 159.769 1.00 43.78  ? 301 LEU D CD2 1 
ATOM   2331  N  N   . ILE A 1 355 ? 107.582 129.625 161.167 1.00 49.88  ? 302 ILE D N   1 
ATOM   2332  C  CA  . ILE A 1 355 ? 106.942 130.710 161.903 1.00 50.52  ? 302 ILE D CA  1 
ATOM   2333  C  C   . ILE A 1 355 ? 106.048 130.160 163.008 1.00 54.22  ? 302 ILE D C   1 
ATOM   2334  O  O   . ILE A 1 355 ? 105.937 130.753 164.087 1.00 57.43  ? 302 ILE D O   1 
ATOM   2335  C  CB  . ILE A 1 355 ? 106.165 131.625 160.942 1.00 48.28  ? 302 ILE D CB  1 
ATOM   2336  C  CG1 . ILE A 1 355 ? 107.131 132.353 160.013 1.00 48.31  ? 302 ILE D CG1 1 
ATOM   2337  C  CG2 . ILE A 1 355 ? 105.354 132.640 161.711 1.00 46.43  ? 302 ILE D CG2 1 
ATOM   2338  C  CD1 . ILE A 1 355 ? 106.453 133.307 159.073 1.00 49.46  ? 302 ILE D CD1 1 
ATOM   2339  N  N   . GLU A 1 356 ? 105.394 129.024 162.764 1.00 54.87  ? 303 GLU D N   1 
ATOM   2340  C  CA  . GLU A 1 356 ? 104.601 128.397 163.813 1.00 56.99  ? 303 GLU D CA  1 
ATOM   2341  C  C   . GLU A 1 356 ? 105.480 127.989 164.984 1.00 61.42  ? 303 GLU D C   1 
ATOM   2342  O  O   . GLU A 1 356 ? 105.096 128.154 166.148 1.00 64.60  ? 303 GLU D O   1 
ATOM   2343  C  CB  . GLU A 1 356 ? 103.851 127.188 163.258 1.00 59.89  ? 303 GLU D CB  1 
ATOM   2344  C  CG  . GLU A 1 356 ? 102.974 126.473 164.267 1.00 64.06  ? 303 GLU D CG  1 
ATOM   2345  C  CD  . GLU A 1 356 ? 103.709 125.386 165.020 1.00 69.51  ? 303 GLU D CD  1 
ATOM   2346  O  OE1 . GLU A 1 356 ? 104.902 125.169 164.739 1.00 70.12  ? 303 GLU D OE1 1 
ATOM   2347  O  OE2 . GLU A 1 356 ? 103.095 124.741 165.892 1.00 73.99  ? 303 GLU D OE2 1 
ATOM   2348  N  N   . PHE A 1 357 ? 106.656 127.433 164.697 1.00 62.42  ? 304 PHE D N   1 
ATOM   2349  C  CA  . PHE A 1 357 ? 107.574 127.093 165.779 1.00 62.90  ? 304 PHE D CA  1 
ATOM   2350  C  C   . PHE A 1 357 ? 108.003 128.335 166.547 1.00 62.36  ? 304 PHE D C   1 
ATOM   2351  O  O   . PHE A 1 357 ? 108.089 128.312 167.779 1.00 65.96  ? 304 PHE D O   1 
ATOM   2352  C  CB  . PHE A 1 357 ? 108.796 126.359 165.237 1.00 62.62  ? 304 PHE D CB  1 
ATOM   2353  C  CG  . PHE A 1 357 ? 109.956 126.353 166.184 1.00 64.60  ? 304 PHE D CG  1 
ATOM   2354  C  CD1 . PHE A 1 357 ? 109.849 125.754 167.425 1.00 63.70  ? 304 PHE D CD1 1 
ATOM   2355  C  CD2 . PHE A 1 357 ? 111.151 126.943 165.837 1.00 65.72  ? 304 PHE D CD2 1 
ATOM   2356  C  CE1 . PHE A 1 357 ? 110.909 125.752 168.299 1.00 62.90  ? 304 PHE D CE1 1 
ATOM   2357  C  CE2 . PHE A 1 357 ? 112.216 126.940 166.708 1.00 67.00  ? 304 PHE D CE2 1 
ATOM   2358  C  CZ  . PHE A 1 357 ? 112.095 126.345 167.940 1.00 64.83  ? 304 PHE D CZ  1 
ATOM   2359  N  N   . ALA A 1 358 ? 108.284 129.428 165.837 1.00 59.75  ? 305 ALA D N   1 
ATOM   2360  C  CA  . ALA A 1 358 ? 108.674 130.659 166.519 1.00 59.52  ? 305 ALA D CA  1 
ATOM   2361  C  C   . ALA A 1 358 ? 107.555 131.169 167.419 1.00 62.97  ? 305 ALA D C   1 
ATOM   2362  O  O   . ALA A 1 358 ? 107.803 131.609 168.548 1.00 64.74  ? 305 ALA D O   1 
ATOM   2363  C  CB  . ALA A 1 358 ? 109.073 131.723 165.501 1.00 55.26  ? 305 ALA D CB  1 
ATOM   2364  N  N   . THR A 1 359 ? 106.313 131.113 166.936 1.00 63.90  ? 306 THR D N   1 
ATOM   2365  C  CA  . THR A 1 359 ? 105.177 131.558 167.735 1.00 61.78  ? 306 THR D CA  1 
ATOM   2366  C  C   . THR A 1 359 ? 104.972 130.672 168.957 1.00 68.14  ? 306 THR D C   1 
ATOM   2367  O  O   . THR A 1 359 ? 104.640 131.166 170.040 1.00 74.25  ? 306 THR D O   1 
ATOM   2368  C  CB  . THR A 1 359 ? 103.917 131.593 166.877 1.00 60.82  ? 306 THR D CB  1 
ATOM   2369  O  OG1 . THR A 1 359 ? 104.067 132.585 165.856 1.00 69.45  ? 306 THR D OG1 1 
ATOM   2370  C  CG2 . THR A 1 359 ? 102.711 131.937 167.717 1.00 61.63  ? 306 THR D CG2 1 
ATOM   2371  N  N   . VAL A 1 360 ? 105.150 129.360 168.804 1.00 67.60  ? 307 VAL D N   1 
ATOM   2372  C  CA  . VAL A 1 360 ? 105.051 128.467 169.957 1.00 68.89  ? 307 VAL D CA  1 
ATOM   2373  C  C   . VAL A 1 360 ? 106.126 128.808 170.978 1.00 71.95  ? 307 VAL D C   1 
ATOM   2374  O  O   . VAL A 1 360 ? 105.855 128.928 172.178 1.00 76.11  ? 307 VAL D O   1 
ATOM   2375  C  CB  . VAL A 1 360 ? 105.146 126.998 169.514 1.00 68.40  ? 307 VAL D CB  1 
ATOM   2376  C  CG1 . VAL A 1 360 ? 105.391 126.104 170.709 1.00 72.59  ? 307 VAL D CG1 1 
ATOM   2377  C  CG2 . VAL A 1 360 ? 103.877 126.582 168.817 1.00 71.83  ? 307 VAL D CG2 1 
ATOM   2378  N  N   . ASN A 1 361 ? 107.361 128.990 170.510 1.00 71.01  ? 308 ASN D N   1 
ATOM   2379  C  CA  . ASN A 1 361 ? 108.463 129.312 171.407 1.00 70.91  ? 308 ASN D CA  1 
ATOM   2380  C  C   . ASN A 1 361 ? 108.245 130.646 172.107 1.00 75.42  ? 308 ASN D C   1 
ATOM   2381  O  O   . ASN A 1 361 ? 108.720 130.842 173.231 1.00 80.20  ? 308 ASN D O   1 
ATOM   2382  C  CB  . ASN A 1 361 ? 109.774 129.323 170.626 1.00 67.81  ? 308 ASN D CB  1 
ATOM   2383  C  CG  . ASN A 1 361 ? 110.973 129.558 171.507 1.00 73.55  ? 308 ASN D CG  1 
ATOM   2384  O  OD1 . ASN A 1 361 ? 111.532 130.652 171.533 1.00 76.71  ? 308 ASN D OD1 1 
ATOM   2385  N  ND2 . ASN A 1 361 ? 111.377 128.530 172.240 1.00 76.15  ? 308 ASN D ND2 1 
ATOM   2386  N  N   . TYR A 1 362 ? 107.544 131.575 171.460 1.00 73.98  ? 309 TYR D N   1 
ATOM   2387  C  CA  . TYR A 1 362 ? 107.217 132.837 172.116 1.00 73.83  ? 309 TYR D CA  1 
ATOM   2388  C  C   . TYR A 1 362 ? 106.269 132.629 173.289 1.00 78.13  ? 309 TYR D C   1 
ATOM   2389  O  O   . TYR A 1 362 ? 106.436 133.251 174.343 1.00 82.28  ? 309 TYR D O   1 
ATOM   2390  C  CB  . TYR A 1 362 ? 106.612 133.806 171.105 1.00 72.15  ? 309 TYR D CB  1 
ATOM   2391  C  CG  . TYR A 1 362 ? 106.134 135.105 171.701 1.00 74.08  ? 309 TYR D CG  1 
ATOM   2392  C  CD1 . TYR A 1 362 ? 107.034 136.063 172.135 1.00 76.13  ? 309 TYR D CD1 1 
ATOM   2393  C  CD2 . TYR A 1 362 ? 104.782 135.381 171.812 1.00 78.05  ? 309 TYR D CD2 1 
ATOM   2394  C  CE1 . TYR A 1 362 ? 106.601 137.256 172.671 1.00 78.81  ? 309 TYR D CE1 1 
ATOM   2395  C  CE2 . TYR A 1 362 ? 104.336 136.570 172.349 1.00 80.44  ? 309 TYR D CE2 1 
ATOM   2396  C  CZ  . TYR A 1 362 ? 105.250 137.504 172.777 1.00 82.01  ? 309 TYR D CZ  1 
ATOM   2397  O  OH  . TYR A 1 362 ? 104.810 138.692 173.312 1.00 81.39  ? 309 TYR D OH  1 
ATOM   2398  N  N   . PHE A 1 363 ? 105.271 131.765 173.130 1.00 79.65  ? 310 PHE D N   1 
ATOM   2399  C  CA  . PHE A 1 363 ? 104.266 131.542 174.161 1.00 82.66  ? 310 PHE D CA  1 
ATOM   2400  C  C   . PHE A 1 363 ? 104.684 130.511 175.198 1.00 87.04  ? 310 PHE D C   1 
ATOM   2401  O  O   . PHE A 1 363 ? 103.932 130.271 176.146 1.00 90.54  ? 310 PHE D O   1 
ATOM   2402  C  CB  . PHE A 1 363 ? 102.942 131.109 173.529 1.00 80.45  ? 310 PHE D CB  1 
ATOM   2403  C  CG  . PHE A 1 363 ? 102.202 132.220 172.849 1.00 79.67  ? 310 PHE D CG  1 
ATOM   2404  C  CD1 . PHE A 1 363 ? 102.306 133.520 173.302 1.00 79.60  ? 310 PHE D CD1 1 
ATOM   2405  C  CD2 . PHE A 1 363 ? 101.399 131.963 171.756 1.00 79.93  ? 310 PHE D CD2 1 
ATOM   2406  C  CE1 . PHE A 1 363 ? 101.622 134.541 172.677 1.00 79.00  ? 310 PHE D CE1 1 
ATOM   2407  C  CE2 . PHE A 1 363 ? 100.715 132.978 171.129 1.00 80.70  ? 310 PHE D CE2 1 
ATOM   2408  C  CZ  . PHE A 1 363 ? 100.827 134.270 171.590 1.00 77.93  ? 310 PHE D CZ  1 
ATOM   2409  N  N   . THR A 1 364 ? 105.848 129.893 175.043 1.00 86.56  ? 311 THR D N   1 
ATOM   2410  C  CA  . THR A 1 364 ? 106.314 128.937 176.035 1.00 89.46  ? 311 THR D CA  1 
ATOM   2411  C  C   . THR A 1 364 ? 106.675 129.652 177.331 1.00 97.09  ? 311 THR D C   1 
ATOM   2412  O  O   . THR A 1 364 ? 107.119 130.804 177.326 1.00 95.87  ? 311 THR D O   1 
ATOM   2413  C  CB  . THR A 1 364 ? 107.522 128.167 175.506 1.00 88.58  ? 311 THR D CB  1 
ATOM   2414  O  OG1 . THR A 1 364 ? 107.243 127.700 174.182 1.00 89.55  ? 311 THR D OG1 1 
ATOM   2415  C  CG2 . THR A 1 364 ? 107.825 126.971 176.391 1.00 87.22  ? 311 THR D CG2 1 
ATOM   2416  N  N   . LYS A 1 365 ? 106.427 128.969 178.452 1.00 100.12 ? 312 LYS D N   1 
ATOM   2417  C  CA  . LYS A 1 365 ? 106.837 129.409 179.783 1.00 103.41 ? 312 LYS D CA  1 
ATOM   2418  C  C   . LYS A 1 365 ? 106.001 130.589 180.271 1.00 104.26 ? 312 LYS D C   1 
ATOM   2419  O  O   . LYS A 1 365 ? 106.141 131.022 181.419 1.00 105.90 ? 312 LYS D O   1 
ATOM   2420  C  CB  . LYS A 1 365 ? 108.331 129.757 179.793 1.00 101.77 ? 312 LYS D CB  1 
ATOM   2421  C  CG  . LYS A 1 365 ? 108.972 129.804 181.168 1.00 103.44 ? 312 LYS D CG  1 
ATOM   2422  C  CD  . LYS A 1 365 ? 110.468 130.063 181.061 1.00 104.83 ? 312 LYS D CD  1 
ATOM   2423  C  CE  . LYS A 1 365 ? 111.103 130.197 182.433 1.00 105.28 ? 312 LYS D CE  1 
ATOM   2424  N  NZ  . LYS A 1 365 ? 112.560 130.475 182.352 1.00 102.62 ? 312 LYS D NZ  1 
ATOM   2425  N  N   . SER A 1 366 ? 105.121 131.111 179.420 1.00 99.98  ? 313 SER D N   1 
ATOM   2426  C  CA  . SER A 1 366 ? 104.215 132.184 179.812 1.00 99.90  ? 313 SER D CA  1 
ATOM   2427  C  C   . SER A 1 366 ? 102.756 131.775 179.713 1.00 102.86 ? 313 SER D C   1 
ATOM   2428  O  O   . SER A 1 366 ? 102.005 131.936 180.680 1.00 105.49 ? 313 SER D O   1 
ATOM   2429  C  CB  . SER A 1 366 ? 104.465 133.433 178.956 1.00 95.67  ? 313 SER D CB  1 
ATOM   2430  O  OG  . SER A 1 366 ? 103.544 134.456 179.292 1.00 95.84  ? 313 SER D OG  1 
ATOM   2431  N  N   . GLN A 1 367 ? 102.331 131.258 178.563 1.00 101.30 ? 385 GLN D N   1 
ATOM   2432  C  CA  . GLN A 1 367 ? 100.975 130.754 178.362 1.00 97.96  ? 385 GLN D CA  1 
ATOM   2433  C  C   . GLN A 1 367 ? 101.072 129.365 177.752 1.00 96.51  ? 385 GLN D C   1 
ATOM   2434  O  O   . GLN A 1 367 ? 100.751 129.165 176.575 1.00 94.20  ? 385 GLN D O   1 
ATOM   2435  C  CB  . GLN A 1 367 ? 100.165 131.686 177.461 1.00 97.18  ? 385 GLN D CB  1 
ATOM   2436  C  CG  . GLN A 1 367 ? 100.135 133.128 177.916 1.00 102.48 ? 385 GLN D CG  1 
ATOM   2437  C  CD  . GLN A 1 367 ? 99.219  133.981 177.066 1.00 105.48 ? 385 GLN D CD  1 
ATOM   2438  O  OE1 . GLN A 1 367 ? 99.176  135.201 177.212 1.00 110.55 ? 385 GLN D OE1 1 
ATOM   2439  N  NE2 . GLN A 1 367 ? 98.479  133.342 176.169 1.00 98.67  ? 385 GLN D NE2 1 
ATOM   2440  N  N   . PRO A 1 368 ? 101.515 128.375 178.530 1.00 99.35  ? 386 PRO D N   1 
ATOM   2441  C  CA  . PRO A 1 368 ? 101.748 127.043 177.951 1.00 98.43  ? 386 PRO D CA  1 
ATOM   2442  C  C   . PRO A 1 368 ? 100.507 126.418 177.342 1.00 95.03  ? 386 PRO D C   1 
ATOM   2443  O  O   . PRO A 1 368 ? 100.626 125.594 176.427 1.00 94.04  ? 386 PRO D O   1 
ATOM   2444  C  CB  . PRO A 1 368 ? 102.269 126.231 179.144 1.00 93.92  ? 386 PRO D CB  1 
ATOM   2445  C  CG  . PRO A 1 368 ? 101.777 126.962 180.346 1.00 95.25  ? 386 PRO D CG  1 
ATOM   2446  C  CD  . PRO A 1 368 ? 101.792 128.406 179.975 1.00 95.64  ? 386 PRO D CD  1 
ATOM   2447  N  N   . ALA A 1 369 ? 99.317  126.781 177.823 1.00 93.42  ? 387 ALA D N   1 
ATOM   2448  C  CA  . ALA A 1 369 ? 98.094  126.256 177.225 1.00 92.10  ? 387 ALA D CA  1 
ATOM   2449  C  C   . ALA A 1 369 ? 97.954  126.700 175.775 1.00 93.07  ? 387 ALA D C   1 
ATOM   2450  O  O   . ALA A 1 369 ? 97.566  125.907 174.910 1.00 92.21  ? 387 ALA D O   1 
ATOM   2451  C  CB  . ALA A 1 369 ? 96.880  126.696 178.041 1.00 86.74  ? 387 ALA D CB  1 
ATOM   2452  N  N   . ARG A 1 370 ? 98.253  127.968 175.492 1.00 91.85  ? 388 ARG D N   1 
ATOM   2453  C  CA  . ARG A 1 370 ? 98.136  128.467 174.127 1.00 87.35  ? 388 ARG D CA  1 
ATOM   2454  C  C   . ARG A 1 370 ? 99.122  127.766 173.203 1.00 85.18  ? 388 ARG D C   1 
ATOM   2455  O  O   . ARG A 1 370 ? 98.781  127.420 172.066 1.00 85.91  ? 388 ARG D O   1 
ATOM   2456  C  CB  . ARG A 1 370 ? 98.353  129.978 174.110 1.00 88.26  ? 388 ARG D CB  1 
ATOM   2457  C  CG  . ARG A 1 370 ? 97.852  130.680 172.865 1.00 85.13  ? 388 ARG D CG  1 
ATOM   2458  C  CD  . ARG A 1 370 ? 97.808  132.180 173.091 1.00 86.34  ? 388 ARG D CD  1 
ATOM   2459  N  NE  . ARG A 1 370 ? 97.251  132.901 171.954 1.00 92.74  ? 388 ARG D NE  1 
ATOM   2460  C  CZ  . ARG A 1 370 ? 97.084  134.216 171.911 1.00 92.64  ? 388 ARG D CZ  1 
ATOM   2461  N  NH1 . ARG A 1 370 ? 97.408  134.988 172.936 1.00 91.70  ? 388 ARG D NH1 1 
ATOM   2462  N  NH2 . ARG A 1 370 ? 96.583  134.771 170.810 1.00 86.56  ? 388 ARG D NH2 1 
ATOM   2463  N  N   . ALA A 1 371 ? 100.351 127.550 173.675 1.00 84.91  ? 389 ALA D N   1 
ATOM   2464  C  CA  . ALA A 1 371 ? 101.331 126.813 172.887 1.00 83.45  ? 389 ALA D CA  1 
ATOM   2465  C  C   . ALA A 1 371 ? 100.877 125.382 172.639 1.00 85.95  ? 389 ALA D C   1 
ATOM   2466  O  O   . ALA A 1 371 ? 101.048 124.848 171.536 1.00 86.69  ? 389 ALA D O   1 
ATOM   2467  C  CB  . ALA A 1 371 ? 102.685 126.827 173.591 1.00 82.32  ? 389 ALA D CB  1 
ATOM   2468  N  N   . ALA A 1 372 ? 100.305 124.740 173.657 1.00 85.04  ? 390 ALA D N   1 
ATOM   2469  C  CA  . ALA A 1 372 ? 99.801  123.385 173.475 1.00 84.38  ? 390 ALA D CA  1 
ATOM   2470  C  C   . ALA A 1 372 ? 98.688  123.348 172.438 1.00 83.52  ? 390 ALA D C   1 
ATOM   2471  O  O   . ALA A 1 372 ? 98.659  122.459 171.581 1.00 83.92  ? 390 ALA D O   1 
ATOM   2472  C  CB  . ALA A 1 372 ? 99.312  122.823 174.808 1.00 86.97  ? 390 ALA D CB  1 
ATOM   2473  N  N   . LYS A 1 373 ? 97.763  124.309 172.501 1.00 84.04  ? 391 LYS D N   1 
ATOM   2474  C  CA  . LYS A 1 373 ? 96.680  124.360 171.525 1.00 83.61  ? 391 LYS D CA  1 
ATOM   2475  C  C   . LYS A 1 373 ? 97.219  124.578 170.120 1.00 80.48  ? 391 LYS D C   1 
ATOM   2476  O  O   . LYS A 1 373 ? 96.762  123.937 169.166 1.00 81.01  ? 391 LYS D O   1 
ATOM   2477  C  CB  . LYS A 1 373 ? 95.686  125.465 171.887 1.00 83.12  ? 391 LYS D CB  1 
ATOM   2478  C  CG  . LYS A 1 373 ? 94.471  125.000 172.680 1.00 88.89  ? 391 LYS D CG  1 
ATOM   2479  C  CD  . LYS A 1 373 ? 94.850  124.538 174.080 1.00 96.73  ? 391 LYS D CD  1 
ATOM   2480  C  CE  . LYS A 1 373 ? 93.622  124.189 174.904 1.00 99.42  ? 391 LYS D CE  1 
ATOM   2481  N  NZ  . LYS A 1 373 ? 93.991  123.740 176.274 1.00 94.94  ? 391 LYS D NZ  1 
ATOM   2482  N  N   . ILE A 1 374 ? 98.195  125.475 169.973 1.00 79.49  ? 392 ILE D N   1 
ATOM   2483  C  CA  . ILE A 1 374 ? 98.758  125.744 168.654 1.00 77.15  ? 392 ILE D CA  1 
ATOM   2484  C  C   . ILE A 1 374 ? 99.419  124.494 168.094 1.00 75.87  ? 392 ILE D C   1 
ATOM   2485  O  O   . ILE A 1 374 ? 99.207  124.131 166.934 1.00 76.03  ? 392 ILE D O   1 
ATOM   2486  C  CB  . ILE A 1 374 ? 99.746  126.920 168.715 1.00 74.77  ? 392 ILE D CB  1 
ATOM   2487  C  CG1 . ILE A 1 374 ? 98.994  128.231 168.928 1.00 70.73  ? 392 ILE D CG1 1 
ATOM   2488  C  CG2 . ILE A 1 374 ? 100.557 126.983 167.442 1.00 72.74  ? 392 ILE D CG2 1 
ATOM   2489  C  CD1 . ILE A 1 374 ? 99.897  129.415 169.133 1.00 71.31  ? 392 ILE D CD1 1 
ATOM   2490  N  N   . ASP A 1 375 ? 100.225 123.811 168.908 1.00 75.44  ? 393 ASP D N   1 
ATOM   2491  C  CA  . ASP A 1 375 ? 100.897 122.610 168.422 1.00 73.97  ? 393 ASP D CA  1 
ATOM   2492  C  C   . ASP A 1 375 ? 99.898  121.514 168.076 1.00 74.94  ? 393 ASP D C   1 
ATOM   2493  O  O   . ASP A 1 375 ? 100.031 120.844 167.043 1.00 77.88  ? 393 ASP D O   1 
ATOM   2494  C  CB  . ASP A 1 375 ? 101.898 122.110 169.460 1.00 78.09  ? 393 ASP D CB  1 
ATOM   2495  C  CG  . ASP A 1 375 ? 103.289 121.965 168.896 1.00 82.35  ? 393 ASP D CG  1 
ATOM   2496  O  OD1 . ASP A 1 375 ? 103.505 122.385 167.742 1.00 84.73  ? 393 ASP D OD1 1 
ATOM   2497  O  OD2 . ASP A 1 375 ? 104.167 121.431 169.602 1.00 81.20  ? 393 ASP D OD2 1 
ATOM   2498  N  N   . ARG A 1 376 ? 98.886  121.321 168.926 1.00 77.04  ? 394 ARG D N   1 
ATOM   2499  C  CA  . ARG A 1 376 ? 97.894  120.280 168.684 1.00 78.13  ? 394 ARG D CA  1 
ATOM   2500  C  C   . ARG A 1 376 ? 97.110  120.547 167.407 1.00 76.59  ? 394 ARG D C   1 
ATOM   2501  O  O   . ARG A 1 376 ? 96.841  119.622 166.631 1.00 73.53  ? 394 ARG D O   1 
ATOM   2502  C  CB  . ARG A 1 376 ? 96.955  120.180 169.885 1.00 84.24  ? 394 ARG D CB  1 
ATOM   2503  C  CG  . ARG A 1 376 ? 95.849  119.154 169.747 1.00 90.55  ? 394 ARG D CG  1 
ATOM   2504  C  CD  . ARG A 1 376 ? 94.900  119.218 170.936 1.00 97.76  ? 394 ARG D CD  1 
ATOM   2505  N  NE  . ARG A 1 376 ? 93.718  118.386 170.744 1.00 112.10 ? 394 ARG D NE  1 
ATOM   2506  C  CZ  . ARG A 1 376 ? 93.623  117.119 171.120 1.00 112.37 ? 394 ARG D CZ  1 
ATOM   2507  N  NH1 . ARG A 1 376 ? 94.628  116.497 171.713 1.00 114.61 ? 394 ARG D NH1 1 
ATOM   2508  N  NH2 . ARG A 1 376 ? 92.490  116.459 170.900 1.00 104.51 ? 394 ARG D NH2 1 
ATOM   2509  N  N   . LEU A 1 377 ? 96.726  121.804 167.172 1.00 76.90  ? 395 LEU D N   1 
ATOM   2510  C  CA  . LEU A 1 377 ? 96.027  122.135 165.937 1.00 75.23  ? 395 LEU D CA  1 
ATOM   2511  C  C   . LEU A 1 377 ? 96.944  122.010 164.727 1.00 70.87  ? 395 LEU D C   1 
ATOM   2512  O  O   . LEU A 1 377 ? 96.520  121.535 163.670 1.00 72.16  ? 395 LEU D O   1 
ATOM   2513  C  CB  . LEU A 1 377 ? 95.442  123.542 166.025 1.00 74.45  ? 395 LEU D CB  1 
ATOM   2514  C  CG  . LEU A 1 377 ? 94.242  123.683 166.958 1.00 71.54  ? 395 LEU D CG  1 
ATOM   2515  C  CD1 . LEU A 1 377 ? 93.762  125.119 167.007 1.00 69.58  ? 395 LEU D CD1 1 
ATOM   2516  C  CD2 . LEU A 1 377 ? 93.129  122.763 166.509 1.00 66.57  ? 395 LEU D CD2 1 
ATOM   2517  N  N   . SER A 1 378 ? 98.203  122.427 164.864 1.00 69.64  ? 396 SER D N   1 
ATOM   2518  C  CA  . SER A 1 378 ? 99.125  122.413 163.735 1.00 69.17  ? 396 SER D CA  1 
ATOM   2519  C  C   . SER A 1 378 ? 99.426  120.995 163.274 1.00 68.81  ? 396 SER D C   1 
ATOM   2520  O  O   . SER A 1 378 ? 99.519  120.739 162.064 1.00 68.91  ? 396 SER D O   1 
ATOM   2521  C  CB  . SER A 1 378 ? 100.410 123.146 164.114 1.00 68.87  ? 396 SER D CB  1 
ATOM   2522  O  OG  . SER A 1 378 ? 101.472 122.789 163.256 1.00 69.78  ? 396 SER D OG  1 
ATOM   2523  N  N   . ARG A 1 379 ? 99.560  120.059 164.222 1.00 70.28  ? 397 ARG D N   1 
ATOM   2524  C  CA  . ARG A 1 379 ? 99.903  118.683 163.872 1.00 72.51  ? 397 ARG D CA  1 
ATOM   2525  C  C   . ARG A 1 379 ? 98.905  118.077 162.897 1.00 73.11  ? 397 ARG D C   1 
ATOM   2526  O  O   . ARG A 1 379 ? 99.250  117.154 162.153 1.00 73.40  ? 397 ARG D O   1 
ATOM   2527  C  CB  . ARG A 1 379 ? 99.977  117.816 165.128 1.00 75.11  ? 397 ARG D CB  1 
ATOM   2528  C  CG  . ARG A 1 379 ? 101.151 118.101 166.035 1.00 77.23  ? 397 ARG D CG  1 
ATOM   2529  C  CD  . ARG A 1 379 ? 101.105 117.218 167.266 1.00 78.54  ? 397 ARG D CD  1 
ATOM   2530  N  NE  . ARG A 1 379 ? 102.163 117.547 168.212 1.00 82.04  ? 397 ARG D NE  1 
ATOM   2531  C  CZ  . ARG A 1 379 ? 102.361 116.919 169.363 1.00 84.77  ? 397 ARG D CZ  1 
ATOM   2532  N  NH1 . ARG A 1 379 ? 101.588 115.916 169.745 1.00 84.47  ? 397 ARG D NH1 1 
ATOM   2533  N  NH2 . ARG A 1 379 ? 103.360 117.307 170.149 1.00 82.86  ? 397 ARG D NH2 1 
ATOM   2534  N  N   . ILE A 1 380 ? 97.670  118.563 162.893 1.00 71.97  ? 398 ILE D N   1 
ATOM   2535  C  CA  . ILE A 1 380 ? 96.667  118.087 161.953 1.00 71.74  ? 398 ILE D CA  1 
ATOM   2536  C  C   . ILE A 1 380 ? 96.393  119.086 160.835 1.00 68.95  ? 398 ILE D C   1 
ATOM   2537  O  O   . ILE A 1 380 ? 95.929  118.674 159.762 1.00 69.03  ? 398 ILE D O   1 
ATOM   2538  C  CB  . ILE A 1 380 ? 95.356  117.714 162.678 1.00 73.22  ? 398 ILE D CB  1 
ATOM   2539  C  CG1 . ILE A 1 380 ? 94.488  116.811 161.799 1.00 76.00  ? 398 ILE D CG1 1 
ATOM   2540  C  CG2 . ILE A 1 380 ? 94.587  118.959 163.084 1.00 69.09  ? 398 ILE D CG2 1 
ATOM   2541  C  CD1 . ILE A 1 380 ? 93.191  116.393 162.446 1.00 72.36  ? 398 ILE D CD1 1 
ATOM   2542  N  N   . ALA A 1 381 ? 96.675  120.373 161.035 1.00 67.38  ? 399 ALA D N   1 
ATOM   2543  C  CA  . ALA A 1 381 ? 96.405  121.348 159.985 1.00 63.45  ? 399 ALA D CA  1 
ATOM   2544  C  C   . ALA A 1 381 ? 97.429  121.261 158.864 1.00 62.77  ? 399 ALA D C   1 
ATOM   2545  O  O   . ALA A 1 381 ? 97.072  121.367 157.687 1.00 64.75  ? 399 ALA D O   1 
ATOM   2546  C  CB  . ALA A 1 381 ? 96.375  122.759 160.565 1.00 64.87  ? 399 ALA D CB  1 
ATOM   2547  N  N   . PHE A 1 382 ? 98.708  121.078 159.202 1.00 61.42  ? 400 PHE D N   1 
ATOM   2548  C  CA  . PHE A 1 382 ? 99.725  121.105 158.151 1.00 59.12  ? 400 PHE D CA  1 
ATOM   2549  C  C   . PHE A 1 382 ? 99.667  119.877 157.249 1.00 60.64  ? 400 PHE D C   1 
ATOM   2550  O  O   . PHE A 1 382 ? 99.574  120.047 156.018 1.00 57.83  ? 400 PHE D O   1 
ATOM   2551  C  CB  . PHE A 1 382 ? 101.112 121.305 158.768 1.00 59.65  ? 400 PHE D CB  1 
ATOM   2552  C  CG  . PHE A 1 382 ? 101.425 122.732 159.111 1.00 59.89  ? 400 PHE D CG  1 
ATOM   2553  C  CD1 . PHE A 1 382 ? 100.854 123.334 160.213 1.00 62.83  ? 400 PHE D CD1 1 
ATOM   2554  C  CD2 . PHE A 1 382 ? 102.301 123.466 158.339 1.00 56.50  ? 400 PHE D CD2 1 
ATOM   2555  C  CE1 . PHE A 1 382 ? 101.145 124.641 160.534 1.00 59.72  ? 400 PHE D CE1 1 
ATOM   2556  C  CE2 . PHE A 1 382 ? 102.594 124.774 158.658 1.00 54.25  ? 400 PHE D CE2 1 
ATOM   2557  C  CZ  . PHE A 1 382 ? 102.014 125.360 159.757 1.00 55.36  ? 400 PHE D CZ  1 
ATOM   2558  N  N   . PRO A 1 383 ? 99.729  118.638 157.758 1.00 61.53  ? 401 PRO D N   1 
ATOM   2559  C  CA  . PRO A 1 383 ? 99.686  117.487 156.839 1.00 59.84  ? 401 PRO D CA  1 
ATOM   2560  C  C   . PRO A 1 383 ? 98.417  117.418 156.013 1.00 61.00  ? 401 PRO D C   1 
ATOM   2561  O  O   . PRO A 1 383 ? 98.467  117.025 154.842 1.00 60.13  ? 401 PRO D O   1 
ATOM   2562  C  CB  . PRO A 1 383 ? 99.813  116.284 157.782 1.00 55.90  ? 401 PRO D CB  1 
ATOM   2563  C  CG  . PRO A 1 383 ? 100.439 116.822 159.003 1.00 56.96  ? 401 PRO D CG  1 
ATOM   2564  C  CD  . PRO A 1 383 ? 99.882  118.194 159.153 1.00 59.33  ? 401 PRO D CD  1 
ATOM   2565  N  N   . LEU A 1 384 ? 97.276  117.796 156.587 1.00 59.87  ? 402 LEU D N   1 
ATOM   2566  C  CA  . LEU A 1 384 ? 96.029  117.746 155.835 1.00 59.36  ? 402 LEU D CA  1 
ATOM   2567  C  C   . LEU A 1 384 ? 96.041  118.733 154.676 1.00 56.75  ? 402 LEU D C   1 
ATOM   2568  O  O   . LEU A 1 384 ? 95.653  118.388 153.555 1.00 57.96  ? 402 LEU D O   1 
ATOM   2569  C  CB  . LEU A 1 384 ? 94.849  118.016 156.766 1.00 61.60  ? 402 LEU D CB  1 
ATOM   2570  C  CG  . LEU A 1 384 ? 93.452  117.811 156.187 1.00 60.55  ? 402 LEU D CG  1 
ATOM   2571  C  CD1 . LEU A 1 384 ? 93.368  116.464 155.501 1.00 58.72  ? 402 LEU D CD1 1 
ATOM   2572  C  CD2 . LEU A 1 384 ? 92.417  117.917 157.286 1.00 59.69  ? 402 LEU D CD2 1 
ATOM   2573  N  N   . LEU A 1 385 ? 96.490  119.963 154.923 1.00 54.42  ? 403 LEU D N   1 
ATOM   2574  C  CA  . LEU A 1 385 ? 96.553  120.946 153.848 1.00 54.61  ? 403 LEU D CA  1 
ATOM   2575  C  C   . LEU A 1 385 ? 97.551  120.531 152.777 1.00 56.77  ? 403 LEU D C   1 
ATOM   2576  O  O   . LEU A 1 385 ? 97.292  120.705 151.581 1.00 59.91  ? 403 LEU D O   1 
ATOM   2577  C  CB  . LEU A 1 385 ? 96.900  122.322 154.409 1.00 54.64  ? 403 LEU D CB  1 
ATOM   2578  C  CG  . LEU A 1 385 ? 95.798  122.979 155.238 1.00 57.08  ? 403 LEU D CG  1 
ATOM   2579  C  CD1 . LEU A 1 385 ? 96.300  124.263 155.864 1.00 53.46  ? 403 LEU D CD1 1 
ATOM   2580  C  CD2 . LEU A 1 385 ? 94.575  123.243 154.386 1.00 57.86  ? 403 LEU D CD2 1 
ATOM   2581  N  N   . PHE A 1 386 ? 98.701  119.983 153.177 1.00 55.04  ? 404 PHE D N   1 
ATOM   2582  C  CA  . PHE A 1 386 ? 99.663  119.554 152.168 1.00 51.71  ? 404 PHE D CA  1 
ATOM   2583  C  C   . PHE A 1 386 ? 99.115  118.405 151.332 1.00 54.07  ? 404 PHE D C   1 
ATOM   2584  O  O   . PHE A 1 386 ? 99.298  118.381 150.109 1.00 53.65  ? 404 PHE D O   1 
ATOM   2585  C  CB  . PHE A 1 386 ? 100.986 119.157 152.811 1.00 51.24  ? 404 PHE D CB  1 
ATOM   2586  C  CG  . PHE A 1 386 ? 102.098 118.976 151.823 1.00 50.99  ? 404 PHE D CG  1 
ATOM   2587  C  CD1 . PHE A 1 386 ? 102.408 119.983 150.926 1.00 49.97  ? 404 PHE D CD1 1 
ATOM   2588  C  CD2 . PHE A 1 386 ? 102.836 117.808 151.791 1.00 50.43  ? 404 PHE D CD2 1 
ATOM   2589  C  CE1 . PHE A 1 386 ? 103.427 119.826 150.015 1.00 50.09  ? 404 PHE D CE1 1 
ATOM   2590  C  CE2 . PHE A 1 386 ? 103.859 117.648 150.880 1.00 51.88  ? 404 PHE D CE2 1 
ATOM   2591  C  CZ  . PHE A 1 386 ? 104.154 118.659 149.992 1.00 50.41  ? 404 PHE D CZ  1 
ATOM   2592  N  N   . GLY A 1 387 ? 98.438  117.448 151.968 1.00 52.71  ? 405 GLY D N   1 
ATOM   2593  C  CA  . GLY A 1 387 ? 97.835  116.363 151.214 1.00 50.33  ? 405 GLY D CA  1 
ATOM   2594  C  C   . GLY A 1 387 ? 96.770  116.848 150.251 1.00 51.48  ? 405 GLY D C   1 
ATOM   2595  O  O   . GLY A 1 387 ? 96.698  116.389 149.108 1.00 55.60  ? 405 GLY D O   1 
ATOM   2596  N  N   . ILE A 1 388 ? 95.938  117.793 150.693 1.00 48.26  ? 406 ILE D N   1 
ATOM   2597  C  CA  . ILE A 1 388 ? 94.911  118.342 149.814 1.00 47.99  ? 406 ILE D CA  1 
ATOM   2598  C  C   . ILE A 1 388 ? 95.547  119.053 148.629 1.00 49.96  ? 406 ILE D C   1 
ATOM   2599  O  O   . ILE A 1 388 ? 95.101  118.905 147.483 1.00 53.34  ? 406 ILE D O   1 
ATOM   2600  C  CB  . ILE A 1 388 ? 93.977  119.275 150.602 1.00 49.86  ? 406 ILE D CB  1 
ATOM   2601  C  CG1 . ILE A 1 388 ? 93.076  118.465 151.530 1.00 50.04  ? 406 ILE D CG1 1 
ATOM   2602  C  CG2 . ILE A 1 388 ? 93.142  120.125 149.662 1.00 47.12  ? 406 ILE D CG2 1 
ATOM   2603  C  CD1 . ILE A 1 388 ? 92.202  119.322 152.402 1.00 54.47  ? 406 ILE D CD1 1 
ATOM   2604  N  N   . PHE A 1 389 ? 96.594  119.841 148.881 1.00 47.96  ? 407 PHE D N   1 
ATOM   2605  C  CA  . PHE A 1 389 ? 97.259  120.539 147.787 1.00 45.07  ? 407 PHE D CA  1 
ATOM   2606  C  C   . PHE A 1 389 ? 97.871  119.562 146.797 1.00 46.90  ? 407 PHE D C   1 
ATOM   2607  O  O   . PHE A 1 389 ? 97.777  119.766 145.585 1.00 48.72  ? 407 PHE D O   1 
ATOM   2608  C  CB  . PHE A 1 389 ? 98.330  121.483 148.325 1.00 44.53  ? 407 PHE D CB  1 
ATOM   2609  C  CG  . PHE A 1 389 ? 99.336  121.900 147.292 1.00 45.19  ? 407 PHE D CG  1 
ATOM   2610  C  CD1 . PHE A 1 389 ? 99.024  122.861 146.351 1.00 44.07  ? 407 PHE D CD1 1 
ATOM   2611  C  CD2 . PHE A 1 389 ? 100.595 121.332 147.263 1.00 46.03  ? 407 PHE D CD2 1 
ATOM   2612  C  CE1 . PHE A 1 389 ? 99.949  123.245 145.402 1.00 44.25  ? 407 PHE D CE1 1 
ATOM   2613  C  CE2 . PHE A 1 389 ? 101.520 121.710 146.315 1.00 43.56  ? 407 PHE D CE2 1 
ATOM   2614  C  CZ  . PHE A 1 389 ? 101.198 122.668 145.385 1.00 44.49  ? 407 PHE D CZ  1 
ATOM   2615  N  N   . ASN A 1 390 ? 98.520  118.505 147.289 1.00 48.29  ? 408 ASN D N   1 
ATOM   2616  C  CA  . ASN A 1 390 ? 99.101  117.528 146.375 1.00 48.15  ? 408 ASN D CA  1 
ATOM   2617  C  C   . ASN A 1 390 ? 98.025  116.852 145.543 1.00 51.16  ? 408 ASN D C   1 
ATOM   2618  O  O   . ASN A 1 390 ? 98.178  116.690 144.325 1.00 54.67  ? 408 ASN D O   1 
ATOM   2619  C  CB  . ASN A 1 390 ? 99.910  116.492 147.146 1.00 47.23  ? 408 ASN D CB  1 
ATOM   2620  C  CG  . ASN A 1 390 ? 101.319 116.946 147.414 1.00 53.82  ? 408 ASN D CG  1 
ATOM   2621  O  OD1 . ASN A 1 390 ? 102.251 116.555 146.719 1.00 53.45  ? 408 ASN D OD1 1 
ATOM   2622  N  ND2 . ASN A 1 390 ? 101.482 117.792 148.416 1.00 56.45  ? 408 ASN D ND2 1 
ATOM   2623  N  N   . LEU A 1 391 ? 96.918  116.471 146.178 1.00 51.89  ? 409 LEU D N   1 
ATOM   2624  C  CA  . LEU A 1 391 ? 95.823  115.853 145.442 1.00 52.77  ? 409 LEU D CA  1 
ATOM   2625  C  C   . LEU A 1 391 ? 95.332  116.769 144.330 1.00 49.45  ? 409 LEU D C   1 
ATOM   2626  O  O   . LEU A 1 391 ? 95.246  116.360 143.166 1.00 52.20  ? 409 LEU D O   1 
ATOM   2627  C  CB  . LEU A 1 391 ? 94.687  115.508 146.405 1.00 54.02  ? 409 LEU D CB  1 
ATOM   2628  C  CG  . LEU A 1 391 ? 93.475  114.760 145.855 1.00 52.84  ? 409 LEU D CG  1 
ATOM   2629  C  CD1 . LEU A 1 391 ? 93.808  113.299 145.610 1.00 49.12  ? 409 LEU D CD1 1 
ATOM   2630  C  CD2 . LEU A 1 391 ? 92.296  114.898 146.796 1.00 50.29  ? 409 LEU D CD2 1 
ATOM   2631  N  N   . VAL A 1 392 ? 95.035  118.026 144.666 1.00 47.14  ? 410 VAL D N   1 
ATOM   2632  C  CA  . VAL A 1 392 ? 94.484  118.952 143.680 1.00 50.52  ? 410 VAL D CA  1 
ATOM   2633  C  C   . VAL A 1 392 ? 95.490  119.236 142.570 1.00 54.41  ? 410 VAL D C   1 
ATOM   2634  O  O   . VAL A 1 392 ? 95.133  119.254 141.389 1.00 59.08  ? 410 VAL D O   1 
ATOM   2635  C  CB  . VAL A 1 392 ? 94.020  120.248 144.363 1.00 47.38  ? 410 VAL D CB  1 
ATOM   2636  C  CG1 . VAL A 1 392 ? 93.555  121.253 143.329 1.00 43.69  ? 410 VAL D CG1 1 
ATOM   2637  C  CG2 . VAL A 1 392 ? 92.910  119.944 145.339 1.00 48.80  ? 410 VAL D CG2 1 
ATOM   2638  N  N   . TYR A 1 393 ? 96.756  119.459 142.925 1.00 50.07  ? 411 TYR D N   1 
ATOM   2639  C  CA  . TYR A 1 393 ? 97.779  119.764 141.930 1.00 48.41  ? 411 TYR D CA  1 
ATOM   2640  C  C   . TYR A 1 393 ? 97.948  118.619 140.940 1.00 51.21  ? 411 TYR D C   1 
ATOM   2641  O  O   . TYR A 1 393 ? 97.954  118.830 139.720 1.00 53.54  ? 411 TYR D O   1 
ATOM   2642  C  CB  . TYR A 1 393 ? 99.096  120.070 142.643 1.00 46.10  ? 411 TYR D CB  1 
ATOM   2643  C  CG  . TYR A 1 393 ? 100.294 120.304 141.754 1.00 45.80  ? 411 TYR D CG  1 
ATOM   2644  C  CD1 . TYR A 1 393 ? 101.101 119.253 141.351 1.00 47.01  ? 411 TYR D CD1 1 
ATOM   2645  C  CD2 . TYR A 1 393 ? 100.639 121.580 141.350 1.00 44.68  ? 411 TYR D CD2 1 
ATOM   2646  C  CE1 . TYR A 1 393 ? 102.195 119.463 140.555 1.00 44.53  ? 411 TYR D CE1 1 
ATOM   2647  C  CE2 . TYR A 1 393 ? 101.735 121.799 140.552 1.00 43.59  ? 411 TYR D CE2 1 
ATOM   2648  C  CZ  . TYR A 1 393 ? 102.509 120.737 140.158 1.00 44.77  ? 411 TYR D CZ  1 
ATOM   2649  O  OH  . TYR A 1 393 ? 103.607 120.950 139.365 1.00 49.05  ? 411 TYR D OH  1 
ATOM   2650  N  N   . TRP A 1 394 ? 98.078  117.391 141.445 1.00 49.89  ? 412 TRP D N   1 
ATOM   2651  C  CA  . TRP A 1 394 ? 98.319  116.273 140.544 1.00 51.44  ? 412 TRP D CA  1 
ATOM   2652  C  C   . TRP A 1 394 ? 97.080  115.948 139.722 1.00 58.09  ? 412 TRP D C   1 
ATOM   2653  O  O   . TRP A 1 394 ? 97.192  115.571 138.550 1.00 61.11  ? 412 TRP D O   1 
ATOM   2654  C  CB  . TRP A 1 394 ? 98.795  115.055 141.328 1.00 48.28  ? 412 TRP D CB  1 
ATOM   2655  C  CG  . TRP A 1 394 ? 100.172 115.221 141.885 1.00 49.57  ? 412 TRP D CG  1 
ATOM   2656  C  CD1 . TRP A 1 394 ? 100.516 115.314 143.195 1.00 52.91  ? 412 TRP D CD1 1 
ATOM   2657  C  CD2 . TRP A 1 394 ? 101.392 115.320 141.143 1.00 52.13  ? 412 TRP D CD2 1 
ATOM   2658  N  NE1 . TRP A 1 394 ? 101.872 115.462 143.321 1.00 53.14  ? 412 TRP D NE1 1 
ATOM   2659  C  CE2 . TRP A 1 394 ? 102.434 115.469 142.073 1.00 50.75  ? 412 TRP D CE2 1 
ATOM   2660  C  CE3 . TRP A 1 394 ? 101.703 115.300 139.784 1.00 52.81  ? 412 TRP D CE3 1 
ATOM   2661  C  CZ2 . TRP A 1 394 ? 103.762 115.595 141.690 1.00 45.63  ? 412 TRP D CZ2 1 
ATOM   2662  C  CZ3 . TRP A 1 394 ? 103.025 115.423 139.406 1.00 51.22  ? 412 TRP D CZ3 1 
ATOM   2663  C  CH2 . TRP A 1 394 ? 104.037 115.569 140.355 1.00 47.06  ? 412 TRP D CH2 1 
ATOM   2664  N  N   . ALA A 1 395 ? 95.888  116.099 140.304 1.00 58.10  ? 413 ALA D N   1 
ATOM   2665  C  CA  . ALA A 1 395 ? 94.674  115.915 139.520 1.00 58.38  ? 413 ALA D CA  1 
ATOM   2666  C  C   . ALA A 1 395 ? 94.580  116.949 138.408 1.00 61.38  ? 413 ALA D C   1 
ATOM   2667  O  O   . ALA A 1 395 ? 94.169  116.632 137.287 1.00 69.34  ? 413 ALA D O   1 
ATOM   2668  C  CB  . ALA A 1 395 ? 93.445  115.990 140.423 1.00 58.28  ? 413 ALA D CB  1 
ATOM   2669  N  N   . THR A 1 396 ? 94.951  118.195 138.702 1.00 57.33  ? 414 THR D N   1 
ATOM   2670  C  CA  . THR A 1 396 ? 94.876  119.249 137.700 1.00 60.81  ? 414 THR D CA  1 
ATOM   2671  C  C   . THR A 1 396 ? 95.860  119.011 136.565 1.00 63.00  ? 414 THR D C   1 
ATOM   2672  O  O   . THR A 1 396 ? 95.523  119.212 135.394 1.00 67.50  ? 414 THR D O   1 
ATOM   2673  C  CB  . THR A 1 396 ? 95.131  120.603 138.355 1.00 58.99  ? 414 THR D CB  1 
ATOM   2674  O  OG1 . THR A 1 396 ? 94.066  120.896 139.267 1.00 60.29  ? 414 THR D OG1 1 
ATOM   2675  C  CG2 . THR A 1 396 ? 95.213  121.701 137.313 1.00 57.85  ? 414 THR D CG2 1 
ATOM   2676  N  N   . TYR A 1 397 ? 97.077  118.583 136.884 1.00 61.79  ? 415 TYR D N   1 
ATOM   2677  C  CA  . TYR A 1 397 ? 98.126  118.500 135.878 1.00 59.89  ? 415 TYR D CA  1 
ATOM   2678  C  C   . TYR A 1 397 ? 98.390  117.084 135.374 1.00 63.58  ? 415 TYR D C   1 
ATOM   2679  O  O   . TYR A 1 397 ? 99.378  116.872 134.669 1.00 66.13  ? 415 TYR D O   1 
ATOM   2680  C  CB  . TYR A 1 397 ? 99.414  119.111 136.422 1.00 53.83  ? 415 TYR D CB  1 
ATOM   2681  C  CG  . TYR A 1 397 ? 99.407  120.618 136.429 1.00 54.37  ? 415 TYR D CG  1 
ATOM   2682  C  CD1 . TYR A 1 397 ? 99.613  121.330 135.264 1.00 55.76  ? 415 TYR D CD1 1 
ATOM   2683  C  CD2 . TYR A 1 397 ? 99.197  121.325 137.599 1.00 54.76  ? 415 TYR D CD2 1 
ATOM   2684  C  CE1 . TYR A 1 397 ? 99.610  122.702 135.260 1.00 56.39  ? 415 TYR D CE1 1 
ATOM   2685  C  CE2 . TYR A 1 397 ? 99.194  122.699 137.606 1.00 54.01  ? 415 TYR D CE2 1 
ATOM   2686  C  CZ  . TYR A 1 397 ? 99.399  123.383 136.432 1.00 56.88  ? 415 TYR D CZ  1 
ATOM   2687  O  OH  . TYR A 1 397 ? 99.398  124.754 136.425 1.00 60.60  ? 415 TYR D OH  1 
ATOM   2688  N  N   . LEU A 1 398 ? 97.543  116.115 135.707 1.00 66.27  ? 416 LEU D N   1 
ATOM   2689  C  CA  . LEU A 1 398 ? 97.679  114.778 135.144 1.00 68.59  ? 416 LEU D CA  1 
ATOM   2690  C  C   . LEU A 1 398 ? 96.464  114.310 134.361 1.00 79.90  ? 416 LEU D C   1 
ATOM   2691  O  O   . LEU A 1 398 ? 96.612  113.471 133.471 1.00 84.75  ? 416 LEU D O   1 
ATOM   2692  C  CB  . LEU A 1 398 ? 97.976  113.753 136.244 1.00 65.98  ? 416 LEU D CB  1 
ATOM   2693  C  CG  . LEU A 1 398 ? 99.376  113.805 136.844 1.00 57.19  ? 416 LEU D CG  1 
ATOM   2694  C  CD1 . LEU A 1 398 ? 99.544  112.689 137.846 1.00 57.95  ? 416 LEU D CD1 1 
ATOM   2695  C  CD2 . LEU A 1 398 ? 100.418 113.711 135.755 1.00 51.23  ? 416 LEU D CD2 1 
ATOM   2696  N  N   . ASN A 1 399 ? 95.274  114.813 134.669 1.00 81.80  ? 417 ASN D N   1 
ATOM   2697  C  CA  . ASN A 1 399 ? 94.083  114.518 133.886 1.00 88.95  ? 417 ASN D CA  1 
ATOM   2698  C  C   . ASN A 1 399 ? 93.911  115.462 132.704 1.00 91.71  ? 417 ASN D C   1 
ATOM   2699  O  O   . ASN A 1 399 ? 92.948  115.317 131.945 1.00 94.29  ? 417 ASN D O   1 
ATOM   2700  C  CB  . ASN A 1 399 ? 92.839  114.572 134.776 1.00 88.85  ? 417 ASN D CB  1 
ATOM   2701  C  CG  . ASN A 1 399 ? 92.730  113.373 135.691 1.00 89.89  ? 417 ASN D CG  1 
ATOM   2702  O  OD1 . ASN A 1 399 ? 93.625  112.530 135.734 1.00 91.37  ? 417 ASN D OD1 1 
ATOM   2703  N  ND2 . ASN A 1 399 ? 91.633  113.290 136.432 1.00 85.34  ? 417 ASN D ND2 1 
ATOM   2704  N  N   . ARG A 1 400 ? 94.815  116.419 132.535 1.00 89.39  ? 418 ARG D N   1 
ATOM   2705  C  CA  . ARG A 1 400 ? 94.762  117.354 131.421 1.00 92.22  ? 418 ARG D CA  1 
ATOM   2706  C  C   . ARG A 1 400 ? 95.562  116.822 130.239 1.00 89.57  ? 418 ARG D C   1 
ATOM   2707  O  O   . ARG A 1 400 ? 96.308  115.852 130.371 1.00 86.23  ? 418 ARG D O   1 
ATOM   2708  C  CB  . ARG A 1 400 ? 95.291  118.721 131.854 1.00 87.18  ? 418 ARG D CB  1 
ATOM   2709  C  CG  . ARG A 1 400 ? 95.496  119.712 130.729 1.00 80.52  ? 418 ARG D CG  1 
ATOM   2710  C  CD  . ARG A 1 400 ? 96.155  120.975 131.253 1.00 76.85  ? 418 ARG D CD  1 
ATOM   2711  N  NE  . ARG A 1 400 ? 95.411  121.553 132.365 1.00 85.16  ? 418 ARG D NE  1 
ATOM   2712  C  CZ  . ARG A 1 400 ? 95.710  122.705 132.950 1.00 82.75  ? 418 ARG D CZ  1 
ATOM   2713  N  NH1 . ARG A 1 400 ? 96.738  123.435 132.554 1.00 76.80  ? 418 ARG D NH1 1 
ATOM   2714  N  NH2 . ARG A 1 400 ? 94.954  123.138 133.953 1.00 83.67  ? 418 ARG D NH2 1 
ATOM   2715  N  N   . ASN B 2 62  ? 156.504 110.903 74.167  1.00 100.36 ? 8   ASN E N   1 
ATOM   2716  C  CA  . ASN B 2 62  ? 155.407 110.389 73.358  1.00 104.74 ? 8   ASN E CA  1 
ATOM   2717  C  C   . ASN B 2 62  ? 154.104 110.401 74.148  1.00 104.86 ? 8   ASN E C   1 
ATOM   2718  O  O   . ASN B 2 62  ? 153.482 109.359 74.356  1.00 100.10 ? 8   ASN E O   1 
ATOM   2719  C  CB  . ASN B 2 62  ? 155.714 108.973 72.871  1.00 103.11 ? 8   ASN E CB  1 
ATOM   2720  C  CG  . ASN B 2 62  ? 154.833 108.552 71.709  1.00 101.70 ? 8   ASN E CG  1 
ATOM   2721  O  OD1 . ASN B 2 62  ? 153.746 109.094 71.509  1.00 94.64  ? 8   ASN E OD1 1 
ATOM   2722  N  ND2 . ASN B 2 62  ? 155.302 107.579 70.934  1.00 99.95  ? 8   ASN E ND2 1 
ATOM   2723  N  N   . MET B 2 63  ? 153.702 111.590 74.596  1.00 102.51 ? 9   MET E N   1 
ATOM   2724  C  CA  . MET B 2 63  ? 152.424 111.762 75.268  1.00 94.64  ? 9   MET E CA  1 
ATOM   2725  C  C   . MET B 2 63  ? 151.268 111.921 74.294  1.00 91.15  ? 9   MET E C   1 
ATOM   2726  O  O   . MET B 2 63  ? 150.112 111.934 74.729  1.00 88.94  ? 9   MET E O   1 
ATOM   2727  C  CB  . MET B 2 63  ? 152.469 112.977 76.195  1.00 95.86  ? 9   MET E CB  1 
ATOM   2728  C  CG  . MET B 2 63  ? 153.599 112.957 77.199  1.00 97.21  ? 9   MET E CG  1 
ATOM   2729  S  SD  . MET B 2 63  ? 153.574 114.425 78.239  1.00 112.32 ? 9   MET E SD  1 
ATOM   2730  C  CE  . MET B 2 63  ? 151.982 114.238 79.023  1.00 95.44  ? 9   MET E CE  1 
ATOM   2731  N  N   . SER B 2 64  ? 151.552 112.056 72.998  1.00 92.21  ? 10  SER E N   1 
ATOM   2732  C  CA  . SER B 2 64  ? 150.482 112.159 72.012  1.00 91.03  ? 10  SER E CA  1 
ATOM   2733  C  C   . SER B 2 64  ? 149.638 110.893 71.993  1.00 88.96  ? 10  SER E C   1 
ATOM   2734  O  O   . SER B 2 64  ? 148.407 110.958 71.915  1.00 85.80  ? 10  SER E O   1 
ATOM   2735  C  CB  . SER B 2 64  ? 151.075 112.437 70.629  1.00 87.88  ? 10  SER E CB  1 
ATOM   2736  O  OG  . SER B 2 64  ? 150.067 112.506 69.637  1.00 84.32  ? 10  SER E OG  1 
ATOM   2737  N  N   . PHE B 2 65  ? 150.286 109.732 72.084  1.00 86.15  ? 11  PHE E N   1 
ATOM   2738  C  CA  . PHE B 2 65  ? 149.560 108.468 72.105  1.00 80.65  ? 11  PHE E CA  1 
ATOM   2739  C  C   . PHE B 2 65  ? 148.650 108.369 73.324  1.00 76.91  ? 11  PHE E C   1 
ATOM   2740  O  O   . PHE B 2 65  ? 147.488 107.958 73.210  1.00 76.15  ? 11  PHE E O   1 
ATOM   2741  C  CB  . PHE B 2 65  ? 150.562 107.316 72.074  1.00 81.11  ? 11  PHE E CB  1 
ATOM   2742  C  CG  . PHE B 2 65  ? 149.936 105.971 71.922  1.00 82.38  ? 11  PHE E CG  1 
ATOM   2743  C  CD1 . PHE B 2 65  ? 149.293 105.622 70.750  1.00 79.67  ? 11  PHE E CD1 1 
ATOM   2744  C  CD2 . PHE B 2 65  ? 150.013 105.042 72.940  1.00 82.59  ? 11  PHE E CD2 1 
ATOM   2745  C  CE1 . PHE B 2 65  ? 148.722 104.378 70.606  1.00 80.20  ? 11  PHE E CE1 1 
ATOM   2746  C  CE2 . PHE B 2 65  ? 149.444 103.796 72.798  1.00 81.93  ? 11  PHE E CE2 1 
ATOM   2747  C  CZ  . PHE B 2 65  ? 148.797 103.464 71.631  1.00 81.67  ? 11  PHE E CZ  1 
ATOM   2748  N  N   . VAL B 2 66  ? 149.156 108.756 74.497  1.00 76.09  ? 12  VAL E N   1 
ATOM   2749  C  CA  . VAL B 2 66  ? 148.351 108.696 75.712  1.00 72.53  ? 12  VAL E CA  1 
ATOM   2750  C  C   . VAL B 2 66  ? 147.183 109.670 75.636  1.00 71.48  ? 12  VAL E C   1 
ATOM   2751  O  O   . VAL B 2 66  ? 146.052 109.334 76.011  1.00 73.37  ? 12  VAL E O   1 
ATOM   2752  C  CB  . VAL B 2 66  ? 149.228 108.960 76.947  1.00 68.67  ? 12  VAL E CB  1 
ATOM   2753  C  CG1 . VAL B 2 66  ? 148.368 109.111 78.180  1.00 66.28  ? 12  VAL E CG1 1 
ATOM   2754  C  CG2 . VAL B 2 66  ? 150.214 107.830 77.135  1.00 68.78  ? 12  VAL E CG2 1 
ATOM   2755  N  N   . LYS B 2 67  ? 147.432 110.892 75.162  1.00 69.65  ? 13  LYS E N   1 
ATOM   2756  C  CA  . LYS B 2 67  ? 146.353 111.866 75.049  1.00 70.28  ? 13  LYS E CA  1 
ATOM   2757  C  C   . LYS B 2 67  ? 145.289 111.395 74.070  1.00 74.53  ? 13  LYS E C   1 
ATOM   2758  O  O   . LYS B 2 67  ? 144.089 111.565 74.316  1.00 73.63  ? 13  LYS E O   1 
ATOM   2759  C  CB  . LYS B 2 67  ? 146.911 113.224 74.627  1.00 74.17  ? 13  LYS E CB  1 
ATOM   2760  C  CG  . LYS B 2 67  ? 145.856 114.289 74.398  1.00 73.98  ? 13  LYS E CG  1 
ATOM   2761  C  CD  . LYS B 2 67  ? 146.495 115.622 74.071  1.00 76.27  ? 13  LYS E CD  1 
ATOM   2762  C  CE  . LYS B 2 67  ? 145.478 116.599 73.504  1.00 82.96  ? 13  LYS E CE  1 
ATOM   2763  N  NZ  . LYS B 2 67  ? 144.398 116.919 74.471  1.00 84.63  ? 13  LYS E NZ  1 
ATOM   2764  N  N   . GLU B 2 68  ? 145.707 110.795 72.953  1.00 78.49  ? 14  GLU E N   1 
ATOM   2765  C  CA  . GLU B 2 68  ? 144.747 110.260 71.996  1.00 77.15  ? 14  GLU E CA  1 
ATOM   2766  C  C   . GLU B 2 68  ? 143.922 109.138 72.609  1.00 73.56  ? 14  GLU E C   1 
ATOM   2767  O  O   . GLU B 2 68  ? 142.705 109.069 72.403  1.00 71.92  ? 14  GLU E O   1 
ATOM   2768  C  CB  . GLU B 2 68  ? 145.476 109.765 70.751  1.00 82.55  ? 14  GLU E CB  1 
ATOM   2769  C  CG  . GLU B 2 68  ? 144.599 108.974 69.805  1.00 93.31  ? 14  GLU E CG  1 
ATOM   2770  C  CD  . GLU B 2 68  ? 145.403 108.191 68.796  1.00 100.23 ? 14  GLU E CD  1 
ATOM   2771  O  OE1 . GLU B 2 68  ? 146.647 108.226 68.879  1.00 94.81  ? 14  GLU E OE1 1 
ATOM   2772  O  OE2 . GLU B 2 68  ? 144.791 107.542 67.922  1.00 106.98 ? 14  GLU E OE2 1 
ATOM   2773  N  N   . THR B 2 69  ? 144.569 108.247 73.365  1.00 73.84  ? 15  THR E N   1 
ATOM   2774  C  CA  . THR B 2 69  ? 143.842 107.164 74.020  1.00 68.06  ? 15  THR E CA  1 
ATOM   2775  C  C   . THR B 2 69  ? 142.818 107.702 75.011  1.00 66.20  ? 15  THR E C   1 
ATOM   2776  O  O   . THR B 2 69  ? 141.677 107.228 75.058  1.00 71.77  ? 15  THR E O   1 
ATOM   2777  C  CB  . THR B 2 69  ? 144.823 106.237 74.732  1.00 68.71  ? 15  THR E CB  1 
ATOM   2778  O  OG1 . THR B 2 69  ? 145.792 105.752 73.796  1.00 71.50  ? 15  THR E OG1 1 
ATOM   2779  C  CG2 . THR B 2 69  ? 144.092 105.067 75.340  1.00 64.88  ? 15  THR E CG2 1 
ATOM   2780  N  N   . VAL B 2 70  ? 143.207 108.693 75.810  1.00 66.06  ? 16  VAL E N   1 
ATOM   2781  C  CA  . VAL B 2 70  ? 142.288 109.244 76.800  1.00 64.96  ? 16  VAL E CA  1 
ATOM   2782  C  C   . VAL B 2 70  ? 141.135 109.973 76.120  1.00 68.64  ? 16  VAL E C   1 
ATOM   2783  O  O   . VAL B 2 70  ? 139.990 109.915 76.583  1.00 68.74  ? 16  VAL E O   1 
ATOM   2784  C  CB  . VAL B 2 70  ? 143.044 110.152 77.783  1.00 64.35  ? 16  VAL E CB  1 
ATOM   2785  C  CG1 . VAL B 2 70  ? 142.073 110.877 78.691  1.00 56.72  ? 16  VAL E CG1 1 
ATOM   2786  C  CG2 . VAL B 2 70  ? 144.006 109.324 78.605  1.00 56.67  ? 16  VAL E CG2 1 
ATOM   2787  N  N   . ASP B 2 71  ? 141.409 110.670 75.015  1.00 69.58  ? 17  ASP E N   1 
ATOM   2788  C  CA  . ASP B 2 71  ? 140.328 111.305 74.266  1.00 68.47  ? 17  ASP E CA  1 
ATOM   2789  C  C   . ASP B 2 71  ? 139.379 110.270 73.684  1.00 67.00  ? 17  ASP E C   1 
ATOM   2790  O  O   . ASP B 2 71  ? 138.161 110.478 73.660  1.00 66.49  ? 17  ASP E O   1 
ATOM   2791  C  CB  . ASP B 2 71  ? 140.896 112.182 73.155  1.00 72.03  ? 17  ASP E CB  1 
ATOM   2792  C  CG  . ASP B 2 71  ? 141.430 113.499 73.668  1.00 82.33  ? 17  ASP E CG  1 
ATOM   2793  O  OD1 . ASP B 2 71  ? 141.426 113.703 74.898  1.00 84.47  ? 17  ASP E OD1 1 
ATOM   2794  O  OD2 . ASP B 2 71  ? 141.851 114.333 72.841  1.00 85.50  ? 17  ASP E OD2 1 
ATOM   2795  N  N   . LYS B 2 72  ? 139.917 109.154 73.192  1.00 67.17  ? 18  LYS E N   1 
ATOM   2796  C  CA  . LYS B 2 72  ? 139.067 108.101 72.652  1.00 64.93  ? 18  LYS E CA  1 
ATOM   2797  C  C   . LYS B 2 72  ? 138.220 107.449 73.737  1.00 63.01  ? 18  LYS E C   1 
ATOM   2798  O  O   . LYS B 2 72  ? 137.083 107.045 73.471  1.00 63.36  ? 18  LYS E O   1 
ATOM   2799  C  CB  . LYS B 2 72  ? 139.921 107.055 71.938  1.00 66.12  ? 18  LYS E CB  1 
ATOM   2800  C  CG  . LYS B 2 72  ? 139.122 105.966 71.244  1.00 76.41  ? 18  LYS E CG  1 
ATOM   2801  C  CD  . LYS B 2 72  ? 140.031 104.941 70.593  1.00 84.27  ? 18  LYS E CD  1 
ATOM   2802  C  CE  . LYS B 2 72  ? 139.225 103.891 69.848  1.00 100.12 ? 18  LYS E CE  1 
ATOM   2803  N  NZ  . LYS B 2 72  ? 140.087 102.829 69.259  1.00 102.80 ? 18  LYS E NZ  1 
ATOM   2804  N  N   . LEU B 2 73  ? 138.753 107.332 74.955  1.00 61.95  ? 19  LEU E N   1 
ATOM   2805  C  CA  . LEU B 2 73  ? 137.990 106.720 76.040  1.00 57.36  ? 19  LEU E CA  1 
ATOM   2806  C  C   . LEU B 2 73  ? 136.742 107.525 76.371  1.00 59.98  ? 19  LEU E C   1 
ATOM   2807  O  O   . LEU B 2 73  ? 135.672 106.954 76.605  1.00 63.53  ? 19  LEU E O   1 
ATOM   2808  C  CB  . LEU B 2 73  ? 138.859 106.575 77.285  1.00 54.23  ? 19  LEU E CB  1 
ATOM   2809  C  CG  . LEU B 2 73  ? 139.919 105.484 77.271  1.00 57.30  ? 19  LEU E CG  1 
ATOM   2810  C  CD1 . LEU B 2 73  ? 140.574 105.395 78.628  1.00 52.65  ? 19  LEU E CD1 1 
ATOM   2811  C  CD2 . LEU B 2 73  ? 139.299 104.161 76.876  1.00 52.79  ? 19  LEU E CD2 1 
ATOM   2812  N  N   . LEU B 2 74  ? 136.859 108.849 76.400  1.00 61.44  ? 20  LEU E N   1 
ATOM   2813  C  CA  . LEU B 2 74  ? 135.777 109.727 76.816  1.00 60.05  ? 20  LEU E CA  1 
ATOM   2814  C  C   . LEU B 2 74  ? 135.007 110.314 75.643  1.00 65.24  ? 20  LEU E C   1 
ATOM   2815  O  O   . LEU B 2 74  ? 134.233 111.255 75.834  1.00 66.30  ? 20  LEU E O   1 
ATOM   2816  C  CB  . LEU B 2 74  ? 136.328 110.854 77.690  1.00 58.03  ? 20  LEU E CB  1 
ATOM   2817  C  CG  . LEU B 2 74  ? 137.175 110.393 78.872  1.00 61.87  ? 20  LEU E CG  1 
ATOM   2818  C  CD1 . LEU B 2 74  ? 137.627 111.569 79.716  1.00 61.14  ? 20  LEU E CD1 1 
ATOM   2819  C  CD2 . LEU B 2 74  ? 136.393 109.413 79.700  1.00 58.21  ? 20  LEU E CD2 1 
ATOM   2820  N  N   . LYS B 2 75  ? 135.199 109.783 74.436  1.00 68.69  ? 21  LYS E N   1 
ATOM   2821  C  CA  . LYS B 2 75  ? 134.556 110.360 73.260  1.00 66.07  ? 21  LYS E CA  1 
ATOM   2822  C  C   . LYS B 2 75  ? 133.057 110.094 73.264  1.00 66.80  ? 21  LYS E C   1 
ATOM   2823  O  O   . LYS B 2 75  ? 132.248 111.028 73.285  1.00 73.61  ? 21  LYS E O   1 
ATOM   2824  C  CB  . LYS B 2 75  ? 135.201 109.805 71.990  1.00 68.95  ? 21  LYS E CB  1 
ATOM   2825  C  CG  . LYS B 2 75  ? 134.708 110.458 70.713  1.00 69.07  ? 21  LYS E CG  1 
ATOM   2826  C  CD  . LYS B 2 75  ? 135.394 109.874 69.496  1.00 68.20  ? 21  LYS E CD  1 
ATOM   2827  C  CE  . LYS B 2 75  ? 134.924 110.560 68.229  1.00 68.51  ? 21  LYS E CE  1 
ATOM   2828  N  NZ  . LYS B 2 75  ? 135.667 110.095 67.029  1.00 67.76  ? 21  LYS E NZ  1 
ATOM   2829  N  N   . GLY B 2 76  ? 132.664 108.825 73.246  1.00 63.22  ? 22  GLY E N   1 
ATOM   2830  C  CA  . GLY B 2 76  ? 131.256 108.480 73.244  1.00 66.40  ? 22  GLY E CA  1 
ATOM   2831  C  C   . GLY B 2 76  ? 130.730 108.086 74.607  1.00 70.64  ? 22  GLY E C   1 
ATOM   2832  O  O   . GLY B 2 76  ? 129.677 107.453 74.713  1.00 71.92  ? 22  GLY E O   1 
ATOM   2833  N  N   . TYR B 2 77  ? 131.459 108.457 75.656  1.00 66.04  ? 23  TYR E N   1 
ATOM   2834  C  CA  . TYR B 2 77  ? 131.116 108.048 77.012  1.00 56.96  ? 23  TYR E CA  1 
ATOM   2835  C  C   . TYR B 2 77  ? 129.867 108.774 77.494  1.00 57.69  ? 23  TYR E C   1 
ATOM   2836  O  O   . TYR B 2 77  ? 129.735 109.987 77.319  1.00 60.84  ? 23  TYR E O   1 
ATOM   2837  C  CB  . TYR B 2 77  ? 132.292 108.331 77.946  1.00 50.78  ? 23  TYR E CB  1 
ATOM   2838  C  CG  . TYR B 2 77  ? 132.166 107.727 79.319  1.00 47.97  ? 23  TYR E CG  1 
ATOM   2839  C  CD1 . TYR B 2 77  ? 131.546 108.418 80.345  1.00 45.39  ? 23  TYR E CD1 1 
ATOM   2840  C  CD2 . TYR B 2 77  ? 132.672 106.471 79.591  1.00 48.60  ? 23  TYR E CD2 1 
ATOM   2841  C  CE1 . TYR B 2 77  ? 131.432 107.876 81.595  1.00 42.80  ? 23  TYR E CE1 1 
ATOM   2842  C  CE2 . TYR B 2 77  ? 132.560 105.918 80.842  1.00 49.34  ? 23  TYR E CE2 1 
ATOM   2843  C  CZ  . TYR B 2 77  ? 131.936 106.626 81.840  1.00 46.17  ? 23  TYR E CZ  1 
ATOM   2844  O  OH  . TYR B 2 77  ? 131.817 106.087 83.094  1.00 46.73  ? 23  TYR E OH  1 
ATOM   2845  N  N   . ASP B 2 78  ? 128.953 108.030 78.111  1.00 53.49  ? 24  ASP E N   1 
ATOM   2846  C  CA  . ASP B 2 78  ? 127.714 108.581 78.650  1.00 50.30  ? 24  ASP E CA  1 
ATOM   2847  C  C   . ASP B 2 78  ? 127.751 108.448 80.165  1.00 49.52  ? 24  ASP E C   1 
ATOM   2848  O  O   . ASP B 2 78  ? 127.637 107.343 80.700  1.00 48.87  ? 24  ASP E O   1 
ATOM   2849  C  CB  . ASP B 2 78  ? 126.495 107.872 78.072  1.00 51.15  ? 24  ASP E CB  1 
ATOM   2850  C  CG  . ASP B 2 78  ? 125.227 108.671 78.250  1.00 53.49  ? 24  ASP E CG  1 
ATOM   2851  O  OD1 . ASP B 2 78  ? 125.208 109.574 79.107  1.00 49.07  ? 24  ASP E OD1 1 
ATOM   2852  O  OD2 . ASP B 2 78  ? 124.246 108.400 77.533  1.00 59.27  ? 24  ASP E OD2 1 
ATOM   2853  N  N   . ILE B 2 79  ? 127.909 109.580 80.848  1.00 46.53  ? 25  ILE E N   1 
ATOM   2854  C  CA  . ILE B 2 79  ? 128.011 109.588 82.300  1.00 41.84  ? 25  ILE E CA  1 
ATOM   2855  C  C   . ILE B 2 79  ? 126.675 109.294 82.968  1.00 46.34  ? 25  ILE E C   1 
ATOM   2856  O  O   . ILE B 2 79  ? 126.645 108.932 84.148  1.00 50.33  ? 25  ILE E O   1 
ATOM   2857  C  CB  . ILE B 2 79  ? 128.585 110.943 82.749  1.00 40.08  ? 25  ILE E CB  1 
ATOM   2858  C  CG1 . ILE B 2 79  ? 128.933 110.944 84.233  1.00 41.41  ? 25  ILE E CG1 1 
ATOM   2859  C  CG2 . ILE B 2 79  ? 127.615 112.060 82.438  1.00 42.88  ? 25  ILE E CG2 1 
ATOM   2860  C  CD1 . ILE B 2 79  ? 129.339 112.289 84.742  1.00 43.03  ? 25  ILE E CD1 1 
ATOM   2861  N  N   . ARG B 2 80  ? 125.566 109.436 82.246  1.00 45.42  ? 26  ARG E N   1 
ATOM   2862  C  CA  . ARG B 2 80  ? 124.243 109.239 82.822  1.00 41.66  ? 26  ARG E CA  1 
ATOM   2863  C  C   . ARG B 2 80  ? 123.894 107.775 83.030  1.00 42.46  ? 26  ARG E C   1 
ATOM   2864  O  O   . ARG B 2 80  ? 122.911 107.485 83.717  1.00 50.39  ? 26  ARG E O   1 
ATOM   2865  C  CB  . ARG B 2 80  ? 123.183 109.891 81.933  1.00 42.85  ? 26  ARG E CB  1 
ATOM   2866  C  CG  . ARG B 2 80  ? 123.309 111.396 81.835  1.00 44.01  ? 26  ARG E CG  1 
ATOM   2867  C  CD  . ARG B 2 80  ? 122.453 111.953 80.721  1.00 44.00  ? 26  ARG E CD  1 
ATOM   2868  N  NE  . ARG B 2 80  ? 122.811 111.388 79.428  1.00 49.80  ? 26  ARG E NE  1 
ATOM   2869  C  CZ  . ARG B 2 80  ? 122.347 111.817 78.263  1.00 50.38  ? 26  ARG E CZ  1 
ATOM   2870  N  NH1 . ARG B 2 80  ? 121.502 112.829 78.188  1.00 45.12  ? 26  ARG E NH1 1 
ATOM   2871  N  NH2 . ARG B 2 80  ? 122.750 111.221 77.146  1.00 51.51  ? 26  ARG E NH2 1 
ATOM   2872  N  N   . LEU B 2 81  ? 124.663 106.853 82.463  1.00 41.00  ? 27  LEU E N   1 
ATOM   2873  C  CA  . LEU B 2 81  ? 124.379 105.429 82.545  1.00 41.00  ? 27  LEU E CA  1 
ATOM   2874  C  C   . LEU B 2 81  ? 125.499 104.720 83.289  1.00 45.25  ? 27  LEU E C   1 
ATOM   2875  O  O   . LEU B 2 81  ? 126.678 105.008 83.075  1.00 48.83  ? 27  LEU E O   1 
ATOM   2876  C  CB  . LEU B 2 81  ? 124.216 104.826 81.152  1.00 42.03  ? 27  LEU E CB  1 
ATOM   2877  C  CG  . LEU B 2 81  ? 123.199 105.496 80.234  1.00 42.07  ? 27  LEU E CG  1 
ATOM   2878  C  CD1 . LEU B 2 81  ? 123.246 104.871 78.864  1.00 40.49  ? 27  LEU E CD1 1 
ATOM   2879  C  CD2 . LEU B 2 81  ? 121.812 105.395 80.810  1.00 43.45  ? 27  LEU E CD2 1 
ATOM   2880  N  N   . ARG B 2 82  ? 125.122 103.798 84.171  1.00 45.15  ? 28  ARG E N   1 
ATOM   2881  C  CA  . ARG B 2 82  ? 126.087 103.002 84.905  1.00 41.21  ? 28  ARG E CA  1 
ATOM   2882  C  C   . ARG B 2 82  ? 126.737 101.976 83.983  1.00 48.69  ? 28  ARG E C   1 
ATOM   2883  O  O   . ARG B 2 82  ? 126.211 101.673 82.911  1.00 53.29  ? 28  ARG E O   1 
ATOM   2884  C  CB  . ARG B 2 82  ? 125.406 102.293 86.071  1.00 37.68  ? 28  ARG E CB  1 
ATOM   2885  C  CG  . ARG B 2 82  ? 124.391 101.247 85.649  1.00 39.46  ? 28  ARG E CG  1 
ATOM   2886  C  CD  . ARG B 2 82  ? 124.027 100.332 86.794  1.00 42.19  ? 28  ARG E CD  1 
ATOM   2887  N  NE  . ARG B 2 82  ? 122.962 99.408  86.432  1.00 48.59  ? 28  ARG E NE  1 
ATOM   2888  C  CZ  . ARG B 2 82  ? 123.152 98.220  85.877  1.00 49.80  ? 28  ARG E CZ  1 
ATOM   2889  N  NH1 . ARG B 2 82  ? 124.363 97.775  85.595  1.00 47.48  ? 28  ARG E NH1 1 
ATOM   2890  N  NH2 . ARG B 2 82  ? 122.100 97.461  85.594  1.00 49.43  ? 28  ARG E NH2 1 
ATOM   2891  N  N   . PRO B 2 83  ? 127.899 101.444 84.360  1.00 42.35  ? 29  PRO E N   1 
ATOM   2892  C  CA  . PRO B 2 83  ? 128.466 100.331 83.595  1.00 44.26  ? 29  PRO E CA  1 
ATOM   2893  C  C   . PRO B 2 83  ? 127.527 99.137  83.602  1.00 49.07  ? 29  PRO E C   1 
ATOM   2894  O  O   . PRO B 2 83  ? 126.902 98.824  84.616  1.00 54.84  ? 29  PRO E O   1 
ATOM   2895  C  CB  . PRO B 2 83  ? 129.777 100.027 84.324  1.00 42.03  ? 29  PRO E CB  1 
ATOM   2896  C  CG  . PRO B 2 83  ? 129.650 100.671 85.643  1.00 39.05  ? 29  PRO E CG  1 
ATOM   2897  C  CD  . PRO B 2 83  ? 128.803 101.871 85.438  1.00 36.44  ? 29  PRO E CD  1 
ATOM   2898  N  N   . ASP B 2 84  ? 127.445 98.464  82.454  1.00 48.64  ? 30  ASP E N   1 
ATOM   2899  C  CA  . ASP B 2 84  ? 126.477 97.389  82.231  1.00 50.02  ? 30  ASP E CA  1 
ATOM   2900  C  C   . ASP B 2 84  ? 125.050 97.864  82.485  1.00 46.90  ? 30  ASP E C   1 
ATOM   2901  O  O   . ASP B 2 84  ? 124.259 97.183  83.136  1.00 51.74  ? 30  ASP E O   1 
ATOM   2902  C  CB  . ASP B 2 84  ? 126.793 96.166  83.090  1.00 54.36  ? 30  ASP E CB  1 
ATOM   2903  C  CG  . ASP B 2 84  ? 128.109 95.527  82.730  1.00 70.31  ? 30  ASP E CG  1 
ATOM   2904  O  OD1 . ASP B 2 84  ? 128.413 95.428  81.523  1.00 78.33  ? 30  ASP E OD1 1 
ATOM   2905  O  OD2 . ASP B 2 84  ? 128.843 95.125  83.655  1.00 76.99  ? 30  ASP E OD2 1 
ATOM   2906  N  N   . PHE B 2 85  ? 124.718 99.045  81.976  1.00 44.78  ? 31  PHE E N   1 
ATOM   2907  C  CA  . PHE B 2 85  ? 123.368 99.567  82.134  1.00 44.72  ? 31  PHE E CA  1 
ATOM   2908  C  C   . PHE B 2 85  ? 122.371 98.661  81.424  1.00 49.19  ? 31  PHE E C   1 
ATOM   2909  O  O   . PHE B 2 85  ? 122.593 98.240  80.286  1.00 52.61  ? 31  PHE E O   1 
ATOM   2910  C  CB  . PHE B 2 85  ? 123.294 100.990 81.586  1.00 42.51  ? 31  PHE E CB  1 
ATOM   2911  C  CG  . PHE B 2 85  ? 121.958 101.649 81.765  1.00 43.33  ? 31  PHE E CG  1 
ATOM   2912  C  CD1 . PHE B 2 85  ? 121.634 102.284 82.949  1.00 45.19  ? 31  PHE E CD1 1 
ATOM   2913  C  CD2 . PHE B 2 85  ? 121.035 101.655 80.740  1.00 41.29  ? 31  PHE E CD2 1 
ATOM   2914  C  CE1 . PHE B 2 85  ? 120.415 102.899 83.106  1.00 41.30  ? 31  PHE E CE1 1 
ATOM   2915  C  CE2 . PHE B 2 85  ? 119.816 102.267 80.896  1.00 40.24  ? 31  PHE E CE2 1 
ATOM   2916  C  CZ  . PHE B 2 85  ? 119.506 102.889 82.080  1.00 40.36  ? 31  PHE E CZ  1 
ATOM   2917  N  N   . GLY B 2 86  ? 121.272 98.354  82.106  1.00 46.93  ? 32  GLY E N   1 
ATOM   2918  C  CA  . GLY B 2 86  ? 120.273 97.459  81.567  1.00 50.70  ? 32  GLY E CA  1 
ATOM   2919  C  C   . GLY B 2 86  ? 120.601 95.990  81.682  1.00 61.02  ? 32  GLY E C   1 
ATOM   2920  O  O   . GLY B 2 86  ? 119.853 95.164  81.149  1.00 64.98  ? 32  GLY E O   1 
ATOM   2921  N  N   . GLY B 2 87  ? 121.687 95.634  82.362  1.00 58.84  ? 33  GLY E N   1 
ATOM   2922  C  CA  . GLY B 2 87  ? 122.098 94.257  82.468  1.00 53.39  ? 33  GLY E CA  1 
ATOM   2923  C  C   . GLY B 2 87  ? 122.403 93.849  83.893  1.00 59.01  ? 33  GLY E C   1 
ATOM   2924  O  O   . GLY B 2 87  ? 121.747 94.285  84.843  1.00 62.48  ? 33  GLY E O   1 
ATOM   2925  N  N   . PRO B 2 88  ? 123.412 92.995  84.068  1.00 57.78  ? 34  PRO E N   1 
ATOM   2926  C  CA  . PRO B 2 88  ? 123.734 92.519  85.407  1.00 57.89  ? 34  PRO E CA  1 
ATOM   2927  C  C   . PRO B 2 88  ? 124.308 93.640  86.253  1.00 59.59  ? 34  PRO E C   1 
ATOM   2928  O  O   . PRO B 2 88  ? 124.870 94.612  85.721  1.00 61.82  ? 34  PRO E O   1 
ATOM   2929  C  CB  . PRO B 2 88  ? 124.776 91.417  85.148  1.00 53.25  ? 34  PRO E CB  1 
ATOM   2930  C  CG  . PRO B 2 88  ? 125.416 91.822  83.886  1.00 57.22  ? 34  PRO E CG  1 
ATOM   2931  C  CD  . PRO B 2 88  ? 124.350 92.481  83.059  1.00 54.83  ? 34  PRO E CD  1 
ATOM   2932  N  N   . PRO B 2 89  ? 124.186 93.553  87.573  1.00 55.09  ? 35  PRO E N   1 
ATOM   2933  C  CA  . PRO B 2 89  ? 124.689 94.626  88.432  1.00 51.50  ? 35  PRO E CA  1 
ATOM   2934  C  C   . PRO B 2 89  ? 126.204 94.716  88.391  1.00 52.80  ? 35  PRO E C   1 
ATOM   2935  O  O   . PRO B 2 89  ? 126.904 93.782  88.001  1.00 58.87  ? 35  PRO E O   1 
ATOM   2936  C  CB  . PRO B 2 89  ? 124.195 94.225  89.824  1.00 48.22  ? 35  PRO E CB  1 
ATOM   2937  C  CG  . PRO B 2 89  ? 123.992 92.761  89.738  1.00 49.36  ? 35  PRO E CG  1 
ATOM   2938  C  CD  . PRO B 2 89  ? 123.528 92.492  88.350  1.00 52.91  ? 35  PRO E CD  1 
ATOM   2939  N  N   . VAL B 2 90  ? 126.703 95.882  88.790  1.00 49.18  ? 36  VAL E N   1 
ATOM   2940  C  CA  . VAL B 2 90  ? 128.131 96.165  88.829  1.00 46.17  ? 36  VAL E CA  1 
ATOM   2941  C  C   . VAL B 2 90  ? 128.618 95.999  90.261  1.00 50.58  ? 36  VAL E C   1 
ATOM   2942  O  O   . VAL B 2 90  ? 128.023 96.546  91.195  1.00 53.20  ? 36  VAL E O   1 
ATOM   2943  C  CB  . VAL B 2 90  ? 128.432 97.576  88.294  1.00 40.79  ? 36  VAL E CB  1 
ATOM   2944  C  CG1 . VAL B 2 90  ? 127.499 98.588  88.909  1.00 40.96  ? 36  VAL E CG1 1 
ATOM   2945  C  CG2 . VAL B 2 90  ? 129.862 97.955  88.575  1.00 39.22  ? 36  VAL E CG2 1 
ATOM   2946  N  N   . CYS B 2 91  ? 129.685 95.225  90.438  1.00 48.48  ? 37  CYS E N   1 
ATOM   2947  C  CA  . CYS B 2 91  ? 130.261 95.010  91.755  1.00 46.72  ? 37  CYS E CA  1 
ATOM   2948  C  C   . CYS B 2 91  ? 131.166 96.171  92.141  1.00 42.58  ? 37  CYS E C   1 
ATOM   2949  O  O   . CYS B 2 91  ? 131.894 96.711  91.307  1.00 47.31  ? 37  CYS E O   1 
ATOM   2950  C  CB  . CYS B 2 91  ? 131.056 93.708  91.780  1.00 50.73  ? 37  CYS E CB  1 
ATOM   2951  S  SG  . CYS B 2 91  ? 130.129 92.264  91.249  1.00 82.90  ? 37  CYS E SG  1 
ATOM   2952  N  N   . VAL B 2 92  ? 131.108 96.559  93.411  1.00 39.29  ? 38  VAL E N   1 
ATOM   2953  C  CA  . VAL B 2 92  ? 131.933 97.629  93.956  1.00 36.27  ? 38  VAL E CA  1 
ATOM   2954  C  C   . VAL B 2 92  ? 132.585 97.116  95.230  1.00 39.98  ? 38  VAL E C   1 
ATOM   2955  O  O   . VAL B 2 92  ? 131.888 96.715  96.166  1.00 44.46  ? 38  VAL E O   1 
ATOM   2956  C  CB  . VAL B 2 92  ? 131.116 98.899  94.242  1.00 30.65  ? 38  VAL E CB  1 
ATOM   2957  C  CG1 . VAL B 2 92  ? 131.996 99.975  94.824  1.00 29.49  ? 38  VAL E CG1 1 
ATOM   2958  C  CG2 . VAL B 2 92  ? 130.447 99.397  92.983  1.00 31.46  ? 38  VAL E CG2 1 
ATOM   2959  N  N   . GLY B 2 93  ? 133.912 97.133  95.269  1.00 36.27  ? 39  GLY E N   1 
ATOM   2960  C  CA  . GLY B 2 93  ? 134.661 96.733  96.450  1.00 35.45  ? 39  GLY E CA  1 
ATOM   2961  C  C   . GLY B 2 93  ? 135.151 97.949  97.215  1.00 35.23  ? 39  GLY E C   1 
ATOM   2962  O  O   . GLY B 2 93  ? 135.609 98.921  96.623  1.00 35.76  ? 39  GLY E O   1 
ATOM   2963  N  N   . MET B 2 94  ? 135.056 97.878  98.539  1.00 34.65  ? 40  MET E N   1 
ATOM   2964  C  CA  . MET B 2 94  ? 135.364 99.000  99.414  1.00 33.72  ? 40  MET E CA  1 
ATOM   2965  C  C   . MET B 2 94  ? 136.595 98.697  100.252 1.00 33.41  ? 40  MET E C   1 
ATOM   2966  O  O   . MET B 2 94  ? 136.750 97.582  100.755 1.00 33.86  ? 40  MET E O   1 
ATOM   2967  C  CB  . MET B 2 94  ? 134.192 99.322  100.341 1.00 38.71  ? 40  MET E CB  1 
ATOM   2968  C  CG  . MET B 2 94  ? 133.281 100.430 99.860  1.00 42.84  ? 40  MET E CG  1 
ATOM   2969  S  SD  . MET B 2 94  ? 132.186 99.920  98.536  1.00 68.25  ? 40  MET E SD  1 
ATOM   2970  C  CE  . MET B 2 94  ? 131.143 101.364 98.423  1.00 40.28  ? 40  MET E CE  1 
ATOM   2971  N  N   . ASN B 2 95  ? 137.466 99.690  100.387 1.00 33.18  ? 41  ASN E N   1 
ATOM   2972  C  CA  . ASN B 2 95  ? 138.554 99.680  101.351 1.00 30.81  ? 41  ASN E CA  1 
ATOM   2973  C  C   . ASN B 2 95  ? 138.452 100.944 102.182 1.00 36.19  ? 41  ASN E C   1 
ATOM   2974  O  O   . ASN B 2 95  ? 138.055 101.996 101.674 1.00 41.52  ? 41  ASN E O   1 
ATOM   2975  C  CB  . ASN B 2 95  ? 139.928 99.633  100.683 1.00 33.67  ? 41  ASN E CB  1 
ATOM   2976  C  CG  . ASN B 2 95  ? 140.174 98.353  99.938  1.00 42.32  ? 41  ASN E CG  1 
ATOM   2977  O  OD1 . ASN B 2 95  ? 140.442 98.367  98.741  1.00 50.46  ? 41  ASN E OD1 1 
ATOM   2978  N  ND2 . ASN B 2 95  ? 140.103 97.235  100.639 1.00 40.36  ? 41  ASN E ND2 1 
ATOM   2979  N  N   . ILE B 2 96  ? 138.795 100.843 103.458 1.00 33.81  ? 42  ILE E N   1 
ATOM   2980  C  CA  . ILE B 2 96  ? 138.816 101.993 104.348 1.00 33.31  ? 42  ILE E CA  1 
ATOM   2981  C  C   . ILE B 2 96  ? 140.112 101.961 105.136 1.00 36.23  ? 42  ILE E C   1 
ATOM   2982  O  O   . ILE B 2 96  ? 140.479 100.920 105.687 1.00 43.76  ? 42  ILE E O   1 
ATOM   2983  C  CB  . ILE B 2 96  ? 137.605 102.010 105.296 1.00 34.33  ? 42  ILE E CB  1 
ATOM   2984  C  CG1 . ILE B 2 96  ? 136.309 102.186 104.514 1.00 32.02  ? 42  ILE E CG1 1 
ATOM   2985  C  CG2 . ILE B 2 96  ? 137.731 103.124 106.293 1.00 34.53  ? 42  ILE E CG2 1 
ATOM   2986  C  CD1 . ILE B 2 96  ? 135.093 102.171 105.388 1.00 33.92  ? 42  ILE E CD1 1 
ATOM   2987  N  N   . ASP B 2 97  ? 140.811 103.089 105.175 1.00 34.38  ? 43  ASP E N   1 
ATOM   2988  C  CA  . ASP B 2 97  ? 141.978 103.266 106.031 1.00 35.28  ? 43  ASP E CA  1 
ATOM   2989  C  C   . ASP B 2 97  ? 141.671 104.398 106.996 1.00 36.22  ? 43  ASP E C   1 
ATOM   2990  O  O   . ASP B 2 97  ? 141.625 105.561 106.593 1.00 39.00  ? 43  ASP E O   1 
ATOM   2991  C  CB  . ASP B 2 97  ? 143.229 103.574 105.218 1.00 37.24  ? 43  ASP E CB  1 
ATOM   2992  C  CG  . ASP B 2 97  ? 143.556 102.492 104.217 1.00 53.96  ? 43  ASP E CG  1 
ATOM   2993  O  OD1 . ASP B 2 97  ? 143.127 101.342 104.418 1.00 57.94  ? 43  ASP E OD1 1 
ATOM   2994  O  OD2 . ASP B 2 97  ? 144.248 102.792 103.225 1.00 59.42  ? 43  ASP E OD2 1 
ATOM   2995  N  N   . ILE B 2 98  ? 141.463 104.065 108.265 1.00 37.23  ? 44  ILE E N   1 
ATOM   2996  C  CA  . ILE B 2 98  ? 141.088 105.056 109.266 1.00 34.37  ? 44  ILE E CA  1 
ATOM   2997  C  C   . ILE B 2 98  ? 142.345 105.789 109.720 1.00 38.48  ? 44  ILE E C   1 
ATOM   2998  O  O   . ILE B 2 98  ? 143.205 105.208 110.382 1.00 47.28  ? 44  ILE E O   1 
ATOM   2999  C  CB  . ILE B 2 98  ? 140.370 104.403 110.448 1.00 33.42  ? 44  ILE E CB  1 
ATOM   3000  C  CG1 . ILE B 2 98  ? 139.014 103.869 110.007 1.00 31.38  ? 44  ILE E CG1 1 
ATOM   3001  C  CG2 . ILE B 2 98  ? 140.195 105.394 111.564 1.00 41.84  ? 44  ILE E CG2 1 
ATOM   3002  C  CD1 . ILE B 2 98  ? 138.352 103.018 111.037 1.00 39.03  ? 44  ILE E CD1 1 
ATOM   3003  N  N   . ALA B 2 99  ? 142.461 107.067 109.358 1.00 34.07  ? 45  ALA E N   1 
ATOM   3004  C  CA  . ALA B 2 99  ? 143.610 107.848 109.795 1.00 35.86  ? 45  ALA E CA  1 
ATOM   3005  C  C   . ALA B 2 99  ? 143.508 108.199 111.272 1.00 44.96  ? 45  ALA E C   1 
ATOM   3006  O  O   . ALA B 2 99  ? 144.481 108.062 112.018 1.00 57.43  ? 45  ALA E O   1 
ATOM   3007  C  CB  . ALA B 2 99  ? 143.741 109.113 108.951 1.00 30.79  ? 45  ALA E CB  1 
ATOM   3008  N  N   . SER B 2 100 ? 142.337 108.650 111.716 1.00 42.33  ? 46  SER E N   1 
ATOM   3009  C  CA  . SER B 2 100 ? 142.179 109.050 113.106 1.00 46.63  ? 46  SER E CA  1 
ATOM   3010  C  C   . SER B 2 100 ? 140.707 109.037 113.478 1.00 43.78  ? 46  SER E C   1 
ATOM   3011  O  O   . SER B 2 100 ? 139.830 109.096 112.617 1.00 43.38  ? 46  SER E O   1 
ATOM   3012  C  CB  . SER B 2 100 ? 142.769 110.439 113.359 1.00 50.34  ? 46  SER E CB  1 
ATOM   3013  O  OG  . SER B 2 100 ? 141.949 111.443 112.793 1.00 42.87  ? 46  SER E OG  1 
ATOM   3014  N  N   . ILE B 2 101 ? 140.452 108.959 114.779 1.00 47.30  ? 47  ILE E N   1 
ATOM   3015  C  CA  . ILE B 2 101 ? 139.120 109.129 115.344 1.00 44.63  ? 47  ILE E CA  1 
ATOM   3016  C  C   . ILE B 2 101 ? 139.189 110.281 116.331 1.00 50.80  ? 47  ILE E C   1 
ATOM   3017  O  O   . ILE B 2 101 ? 139.909 110.208 117.332 1.00 56.55  ? 47  ILE E O   1 
ATOM   3018  C  CB  . ILE B 2 101 ? 138.607 107.855 116.027 1.00 39.32  ? 47  ILE E CB  1 
ATOM   3019  C  CG1 . ILE B 2 101 ? 138.370 106.762 114.989 1.00 45.26  ? 47  ILE E CG1 1 
ATOM   3020  C  CG2 . ILE B 2 101 ? 137.327 108.146 116.767 1.00 36.21  ? 47  ILE E CG2 1 
ATOM   3021  C  CD1 . ILE B 2 101 ? 137.563 105.597 115.494 1.00 38.51  ? 47  ILE E CD1 1 
ATOM   3022  N  N   . ASP B 2 102 ? 138.456 111.341 116.042 1.00 51.48  ? 48  ASP E N   1 
ATOM   3023  C  CA  . ASP B 2 102 ? 138.463 112.551 116.844 1.00 49.88  ? 48  ASP E CA  1 
ATOM   3024  C  C   . ASP B 2 102 ? 137.425 112.428 117.955 1.00 52.55  ? 48  ASP E C   1 
ATOM   3025  O  O   . ASP B 2 102 ? 136.977 111.331 118.293 1.00 57.13  ? 48  ASP E O   1 
ATOM   3026  C  CB  . ASP B 2 102 ? 138.231 113.766 115.956 1.00 57.76  ? 48  ASP E CB  1 
ATOM   3027  C  CG  . ASP B 2 102 ? 139.273 113.894 114.873 1.00 66.85  ? 48  ASP E CG  1 
ATOM   3028  O  OD1 . ASP B 2 102 ? 140.462 114.069 115.214 1.00 70.34  ? 48  ASP E OD1 1 
ATOM   3029  O  OD2 . ASP B 2 102 ? 138.907 113.801 113.683 1.00 61.30  ? 48  ASP E OD2 1 
ATOM   3030  N  N   . MET B 2 103 ? 137.051 113.562 118.541 1.00 56.21  ? 49  MET E N   1 
ATOM   3031  C  CA  . MET B 2 103 ? 136.261 113.587 119.764 1.00 59.54  ? 49  MET E CA  1 
ATOM   3032  C  C   . MET B 2 103 ? 135.019 112.713 119.667 1.00 53.32  ? 49  MET E C   1 
ATOM   3033  O  O   . MET B 2 103 ? 134.311 112.718 118.659 1.00 54.98  ? 49  MET E O   1 
ATOM   3034  C  CB  . MET B 2 103 ? 135.861 115.026 120.081 1.00 65.42  ? 49  MET E CB  1 
ATOM   3035  C  CG  . MET B 2 103 ? 135.195 115.746 118.925 1.00 63.33  ? 49  MET E CG  1 
ATOM   3036  S  SD  . MET B 2 103 ? 135.063 117.518 119.211 1.00 106.89 ? 49  MET E SD  1 
ATOM   3037  C  CE  . MET B 2 103 ? 136.787 117.993 119.156 1.00 87.67  ? 49  MET E CE  1 
ATOM   3038  N  N   . VAL B 2 104 ? 134.774 111.947 120.725 1.00 48.41  ? 50  VAL E N   1 
ATOM   3039  C  CA  . VAL B 2 104 ? 133.579 111.113 120.851 1.00 46.42  ? 50  VAL E CA  1 
ATOM   3040  C  C   . VAL B 2 104 ? 132.683 111.813 121.866 1.00 54.14  ? 50  VAL E C   1 
ATOM   3041  O  O   . VAL B 2 104 ? 132.789 111.601 123.073 1.00 62.08  ? 50  VAL E O   1 
ATOM   3042  C  CB  . VAL B 2 104 ? 133.922 109.690 121.276 1.00 41.55  ? 50  VAL E CB  1 
ATOM   3043  C  CG1 . VAL B 2 104 ? 132.662 108.872 121.431 1.00 38.65  ? 50  VAL E CG1 1 
ATOM   3044  C  CG2 . VAL B 2 104 ? 134.851 109.057 120.273 1.00 43.49  ? 50  VAL E CG2 1 
ATOM   3045  N  N   . SER B 2 105 ? 131.778 112.650 121.373 1.00 51.17  ? 51  SER E N   1 
ATOM   3046  C  CA  . SER B 2 105 ? 131.024 113.548 122.236 1.00 53.34  ? 51  SER E CA  1 
ATOM   3047  C  C   . SER B 2 105 ? 129.839 112.823 122.858 1.00 54.49  ? 51  SER E C   1 
ATOM   3048  O  O   . SER B 2 105 ? 128.983 112.297 122.142 1.00 52.56  ? 51  SER E O   1 
ATOM   3049  C  CB  . SER B 2 105 ? 130.547 114.758 121.441 1.00 53.17  ? 51  SER E CB  1 
ATOM   3050  O  OG  . SER B 2 105 ? 129.788 115.627 122.254 1.00 58.21  ? 51  SER E OG  1 
ATOM   3051  N  N   . GLU B 2 106 ? 129.783 112.806 124.191 1.00 57.03  ? 52  GLU E N   1 
ATOM   3052  C  CA  . GLU B 2 106 ? 128.607 112.312 124.894 1.00 54.78  ? 52  GLU E CA  1 
ATOM   3053  C  C   . GLU B 2 106 ? 127.482 113.333 124.924 1.00 55.07  ? 52  GLU E C   1 
ATOM   3054  O  O   . GLU B 2 106 ? 126.344 112.971 125.232 1.00 53.45  ? 52  GLU E O   1 
ATOM   3055  C  CB  . GLU B 2 106 ? 128.955 111.917 126.331 1.00 54.97  ? 52  GLU E CB  1 
ATOM   3056  C  CG  . GLU B 2 106 ? 129.967 110.798 126.463 1.00 56.35  ? 52  GLU E CG  1 
ATOM   3057  C  CD  . GLU B 2 106 ? 131.392 111.298 126.444 1.00 71.05  ? 52  GLU E CD  1 
ATOM   3058  O  OE1 . GLU B 2 106 ? 131.593 112.527 126.502 1.00 75.96  ? 52  GLU E OE1 1 
ATOM   3059  O  OE2 . GLU B 2 106 ? 132.314 110.461 126.371 1.00 69.33  ? 52  GLU E OE2 1 
ATOM   3060  N  N   . VAL B 2 107 ? 127.776 114.593 124.613 1.00 55.93  ? 53  VAL E N   1 
ATOM   3061  C  CA  . VAL B 2 107 ? 126.753 115.628 124.613 1.00 57.72  ? 53  VAL E CA  1 
ATOM   3062  C  C   . VAL B 2 107 ? 126.004 115.639 123.291 1.00 61.19  ? 53  VAL E C   1 
ATOM   3063  O  O   . VAL B 2 107 ? 124.769 115.656 123.257 1.00 63.88  ? 53  VAL E O   1 
ATOM   3064  C  CB  . VAL B 2 107 ? 127.392 116.995 124.907 1.00 57.48  ? 53  VAL E CB  1 
ATOM   3065  C  CG1 . VAL B 2 107 ? 126.323 118.036 125.156 1.00 58.98  ? 53  VAL E CG1 1 
ATOM   3066  C  CG2 . VAL B 2 107 ? 128.327 116.893 126.086 1.00 65.28  ? 53  VAL E CG2 1 
ATOM   3067  N  N   . ASN B 2 108 ? 126.740 115.631 122.182 1.00 59.68  ? 54  ASN E N   1 
ATOM   3068  C  CA  . ASN B 2 108 ? 126.139 115.659 120.858 1.00 52.74  ? 54  ASN E CA  1 
ATOM   3069  C  C   . ASN B 2 108 ? 125.715 114.285 120.367 1.00 53.10  ? 54  ASN E C   1 
ATOM   3070  O  O   . ASN B 2 108 ? 125.011 114.204 119.358 1.00 54.51  ? 54  ASN E O   1 
ATOM   3071  C  CB  . ASN B 2 108 ? 127.114 116.273 119.858 1.00 51.31  ? 54  ASN E CB  1 
ATOM   3072  C  CG  . ASN B 2 108 ? 127.573 117.649 120.267 1.00 58.87  ? 54  ASN E CG  1 
ATOM   3073  O  OD1 . ASN B 2 108 ? 128.765 117.898 120.418 1.00 59.29  ? 54  ASN E OD1 1 
ATOM   3074  N  ND2 . ASN B 2 108 ? 126.625 118.557 120.442 1.00 65.14  ? 54  ASN E ND2 1 
ATOM   3075  N  N   . MET B 2 109 ? 126.119 113.216 121.053 1.00 52.59  ? 55  MET E N   1 
ATOM   3076  C  CA  . MET B 2 109 ? 125.784 111.847 120.663 1.00 50.82  ? 55  MET E CA  1 
ATOM   3077  C  C   . MET B 2 109 ? 126.299 111.528 119.260 1.00 53.57  ? 55  MET E C   1 
ATOM   3078  O  O   . MET B 2 109 ? 125.565 111.036 118.404 1.00 57.63  ? 55  MET E O   1 
ATOM   3079  C  CB  . MET B 2 109 ? 124.277 111.600 120.763 1.00 50.77  ? 55  MET E CB  1 
ATOM   3080  C  CG  . MET B 2 109 ? 123.729 111.604 122.172 1.00 52.74  ? 55  MET E CG  1 
ATOM   3081  S  SD  . MET B 2 109 ? 124.048 110.068 123.039 1.00 65.81  ? 55  MET E SD  1 
ATOM   3082  C  CE  . MET B 2 109 ? 123.275 110.403 124.614 1.00 61.25  ? 55  MET E CE  1 
ATOM   3083  N  N   . ASP B 2 110 ? 127.578 111.809 119.028 1.00 49.99  ? 56  ASP E N   1 
ATOM   3084  C  CA  . ASP B 2 110 ? 128.183 111.535 117.733 1.00 44.62  ? 56  ASP E CA  1 
ATOM   3085  C  C   . ASP B 2 110 ? 129.688 111.402 117.905 1.00 47.70  ? 56  ASP E C   1 
ATOM   3086  O  O   . ASP B 2 110 ? 130.236 111.665 118.975 1.00 55.44  ? 56  ASP E O   1 
ATOM   3087  C  CB  . ASP B 2 110 ? 127.822 112.614 116.705 1.00 43.09  ? 56  ASP E CB  1 
ATOM   3088  C  CG  . ASP B 2 110 ? 128.236 114.007 117.129 1.00 54.51  ? 56  ASP E CG  1 
ATOM   3089  O  OD1 . ASP B 2 110 ? 129.090 114.150 118.021 1.00 56.38  ? 56  ASP E OD1 1 
ATOM   3090  O  OD2 . ASP B 2 110 ? 127.699 114.975 116.557 1.00 57.58  ? 56  ASP E OD2 1 
ATOM   3091  N  N   . TYR B 2 111 ? 130.346 110.962 116.835 1.00 41.07  ? 57  TYR E N   1 
ATOM   3092  C  CA  . TYR B 2 111 ? 131.800 110.875 116.793 1.00 37.78  ? 57  TYR E CA  1 
ATOM   3093  C  C   . TYR B 2 111 ? 132.281 111.382 115.442 1.00 40.24  ? 57  TYR E C   1 
ATOM   3094  O  O   . TYR B 2 111 ? 131.492 111.594 114.526 1.00 42.18  ? 57  TYR E O   1 
ATOM   3095  C  CB  . TYR B 2 111 ? 132.295 109.450 117.053 1.00 33.19  ? 57  TYR E CB  1 
ATOM   3096  C  CG  . TYR B 2 111 ? 131.894 108.449 116.002 1.00 38.11  ? 57  TYR E CG  1 
ATOM   3097  C  CD1 . TYR B 2 111 ? 130.639 107.874 116.011 1.00 44.30  ? 57  TYR E CD1 1 
ATOM   3098  C  CD2 . TYR B 2 111 ? 132.780 108.065 115.013 1.00 38.30  ? 57  TYR E CD2 1 
ATOM   3099  C  CE1 . TYR B 2 111 ? 130.275 106.961 115.058 1.00 45.25  ? 57  TYR E CE1 1 
ATOM   3100  C  CE2 . TYR B 2 111 ? 132.425 107.154 114.059 1.00 37.78  ? 57  TYR E CE2 1 
ATOM   3101  C  CZ  . TYR B 2 111 ? 131.172 106.606 114.084 1.00 39.90  ? 57  TYR E CZ  1 
ATOM   3102  O  OH  . TYR B 2 111 ? 130.810 105.692 113.131 1.00 41.81  ? 57  TYR E OH  1 
ATOM   3103  N  N   . THR B 2 112 ? 133.588 111.593 115.323 1.00 40.10  ? 58  THR E N   1 
ATOM   3104  C  CA  . THR B 2 112 ? 134.191 112.086 114.093 1.00 36.06  ? 58  THR E CA  1 
ATOM   3105  C  C   . THR B 2 112 ? 135.228 111.089 113.599 1.00 40.69  ? 58  THR E C   1 
ATOM   3106  O  O   . THR B 2 112 ? 135.936 110.469 114.395 1.00 49.10  ? 58  THR E O   1 
ATOM   3107  C  CB  . THR B 2 112 ? 134.838 113.454 114.300 1.00 36.87  ? 58  THR E CB  1 
ATOM   3108  O  OG1 . THR B 2 112 ? 133.911 114.323 114.954 1.00 39.83  ? 58  THR E OG1 1 
ATOM   3109  C  CG2 . THR B 2 112 ? 135.214 114.071 112.976 1.00 38.08  ? 58  THR E CG2 1 
ATOM   3110  N  N   . LEU B 2 113 ? 135.311 110.935 112.283 1.00 36.50  ? 59  LEU E N   1 
ATOM   3111  C  CA  . LEU B 2 113 ? 136.151 109.919 111.670 1.00 31.04  ? 59  LEU E CA  1 
ATOM   3112  C  C   . LEU B 2 113 ? 136.814 110.496 110.432 1.00 34.02  ? 59  LEU E C   1 
ATOM   3113  O  O   . LEU B 2 113 ? 136.136 111.074 109.581 1.00 38.39  ? 59  LEU E O   1 
ATOM   3114  C  CB  . LEU B 2 113 ? 135.305 108.694 111.309 1.00 28.89  ? 59  LEU E CB  1 
ATOM   3115  C  CG  . LEU B 2 113 ? 135.958 107.483 110.662 1.00 34.60  ? 59  LEU E CG  1 
ATOM   3116  C  CD1 . LEU B 2 113 ? 136.971 106.897 111.593 1.00 42.57  ? 59  LEU E CD1 1 
ATOM   3117  C  CD2 . LEU B 2 113 ? 134.906 106.456 110.350 1.00 39.37  ? 59  LEU E CD2 1 
ATOM   3118  N  N   . THR B 2 114 ? 138.132 110.353 110.336 1.00 33.38  ? 60  THR E N   1 
ATOM   3119  C  CA  . THR B 2 114 ? 138.876 110.701 109.132 1.00 28.71  ? 60  THR E CA  1 
ATOM   3120  C  C   . THR B 2 114 ? 139.361 109.423 108.470 1.00 33.61  ? 60  THR E C   1 
ATOM   3121  O  O   . THR B 2 114 ? 140.019 108.601 109.112 1.00 39.73  ? 60  THR E O   1 
ATOM   3122  C  CB  . THR B 2 114 ? 140.072 111.598 109.443 1.00 30.63  ? 60  THR E CB  1 
ATOM   3123  O  OG1 . THR B 2 114 ? 139.632 112.757 110.154 1.00 38.96  ? 60  THR E OG1 1 
ATOM   3124  C  CG2 . THR B 2 114 ? 140.738 112.032 108.165 1.00 26.17  ? 60  THR E CG2 1 
ATOM   3125  N  N   . MET B 2 115 ? 139.052 109.259 107.189 1.00 27.98  ? 61  MET E N   1 
ATOM   3126  C  CA  . MET B 2 115 ? 139.389 108.008 106.535 1.00 25.59  ? 61  MET E CA  1 
ATOM   3127  C  C   . MET B 2 115 ? 139.758 108.238 105.081 1.00 27.59  ? 61  MET E C   1 
ATOM   3128  O  O   . MET B 2 115 ? 139.272 109.167 104.433 1.00 31.90  ? 61  MET E O   1 
ATOM   3129  C  CB  . MET B 2 115 ? 138.231 107.018 106.629 1.00 29.11  ? 61  MET E CB  1 
ATOM   3130  C  CG  . MET B 2 115 ? 136.945 107.547 106.046 1.00 31.59  ? 61  MET E CG  1 
ATOM   3131  S  SD  . MET B 2 115 ? 135.572 106.423 106.276 1.00 52.98  ? 61  MET E SD  1 
ATOM   3132  C  CE  . MET B 2 115 ? 134.242 107.435 105.664 1.00 39.37  ? 61  MET E CE  1 
ATOM   3133  N  N   . TYR B 2 116 ? 140.636 107.376 104.587 1.00 28.83  ? 62  TYR E N   1 
ATOM   3134  C  CA  . TYR B 2 116 ? 140.863 107.198 103.159 1.00 25.99  ? 62  TYR E CA  1 
ATOM   3135  C  C   . TYR B 2 116 ? 139.889 106.129 102.686 1.00 32.04  ? 62  TYR E C   1 
ATOM   3136  O  O   . TYR B 2 116 ? 140.003 104.965 103.077 1.00 41.18  ? 62  TYR E O   1 
ATOM   3137  C  CB  . TYR B 2 116 ? 142.304 106.778 102.885 1.00 27.85  ? 62  TYR E CB  1 
ATOM   3138  C  CG  . TYR B 2 116 ? 143.367 107.738 103.367 1.00 26.87  ? 62  TYR E CG  1 
ATOM   3139  C  CD1 . TYR B 2 116 ? 143.712 107.809 104.706 1.00 28.91  ? 62  TYR E CD1 1 
ATOM   3140  C  CD2 . TYR B 2 116 ? 144.047 108.547 102.479 1.00 22.54  ? 62  TYR E CD2 1 
ATOM   3141  C  CE1 . TYR B 2 116 ? 144.685 108.671 105.145 1.00 29.59  ? 62  TYR E CE1 1 
ATOM   3142  C  CE2 . TYR B 2 116 ? 145.024 109.411 102.910 1.00 24.08  ? 62  TYR E CE2 1 
ATOM   3143  C  CZ  . TYR B 2 116 ? 145.338 109.470 104.243 1.00 29.39  ? 62  TYR E CZ  1 
ATOM   3144  O  OH  . TYR B 2 116 ? 146.311 110.335 104.676 1.00 33.67  ? 62  TYR E OH  1 
ATOM   3145  N  N   . PHE B 2 117 ? 138.933 106.520 101.854 1.00 27.87  ? 63  PHE E N   1 
ATOM   3146  C  CA  . PHE B 2 117 ? 137.840 105.658 101.422 1.00 30.36  ? 63  PHE E CA  1 
ATOM   3147  C  C   . PHE B 2 117 ? 138.032 105.341 99.945  1.00 32.83  ? 63  PHE E C   1 
ATOM   3148  O  O   . PHE B 2 117 ? 137.956 106.240 99.103  1.00 38.61  ? 63  PHE E O   1 
ATOM   3149  C  CB  . PHE B 2 117 ? 136.507 106.354 101.681 1.00 32.06  ? 63  PHE E CB  1 
ATOM   3150  C  CG  . PHE B 2 117 ? 135.312 105.546 101.306 1.00 37.54  ? 63  PHE E CG  1 
ATOM   3151  C  CD1 . PHE B 2 117 ? 135.006 104.387 101.977 1.00 42.30  ? 63  PHE E CD1 1 
ATOM   3152  C  CD2 . PHE B 2 117 ? 134.474 105.965 100.298 1.00 34.56  ? 63  PHE E CD2 1 
ATOM   3153  C  CE1 . PHE B 2 117 ? 133.903 103.651 101.632 1.00 40.65  ? 63  PHE E CE1 1 
ATOM   3154  C  CE2 . PHE B 2 117 ? 133.371 105.234 99.956  1.00 31.32  ? 63  PHE E CE2 1 
ATOM   3155  C  CZ  . PHE B 2 117 ? 133.086 104.076 100.621 1.00 34.41  ? 63  PHE E CZ  1 
ATOM   3156  N  N   . GLN B 2 118 ? 138.289 104.072 99.630  1.00 29.61  ? 64  GLN E N   1 
ATOM   3157  C  CA  . GLN B 2 118 ? 138.569 103.641 98.268  1.00 33.12  ? 64  GLN E CA  1 
ATOM   3158  C  C   . GLN B 2 118 ? 137.456 102.747 97.745  1.00 34.92  ? 64  GLN E C   1 
ATOM   3159  O  O   . GLN B 2 118 ? 136.979 101.857 98.453  1.00 38.80  ? 64  GLN E O   1 
ATOM   3160  C  CB  . GLN B 2 118 ? 139.891 102.878 98.180  1.00 33.76  ? 64  GLN E CB  1 
ATOM   3161  C  CG  . GLN B 2 118 ? 141.123 103.738 98.188  1.00 36.86  ? 64  GLN E CG  1 
ATOM   3162  C  CD  . GLN B 2 118 ? 141.605 104.035 99.582  1.00 45.63  ? 64  GLN E CD  1 
ATOM   3163  O  OE1 . GLN B 2 118 ? 141.369 103.264 100.509 1.00 42.88  ? 64  GLN E OE1 1 
ATOM   3164  N  NE2 . GLN B 2 118 ? 142.290 105.157 99.741  1.00 48.11  ? 64  GLN E NE2 1 
ATOM   3165  N  N   . GLN B 2 119 ? 137.075 102.972 96.491  1.00 33.22  ? 65  GLN E N   1 
ATOM   3166  C  CA  . GLN B 2 119 ? 136.092 102.163 95.788  1.00 32.37  ? 65  GLN E CA  1 
ATOM   3167  C  C   . GLN B 2 119 ? 136.715 101.598 94.520  1.00 33.29  ? 65  GLN E C   1 
ATOM   3168  O  O   . GLN B 2 119 ? 137.495 102.271 93.841  1.00 36.70  ? 65  GLN E O   1 
ATOM   3169  C  CB  . GLN B 2 119 ? 134.848 102.977 95.459  1.00 30.02  ? 65  GLN E CB  1 
ATOM   3170  C  CG  . GLN B 2 119 ? 134.157 103.525 96.686  1.00 32.77  ? 65  GLN E CG  1 
ATOM   3171  C  CD  . GLN B 2 119 ? 133.005 104.430 96.352  1.00 34.45  ? 65  GLN E CD  1 
ATOM   3172  O  OE1 . GLN B 2 119 ? 131.868 104.153 96.705  1.00 42.70  ? 65  GLN E OE1 1 
ATOM   3173  N  NE2 . GLN B 2 119 ? 133.293 105.525 95.673  1.00 31.41  ? 65  GLN E NE2 1 
ATOM   3174  N  N   . TYR B 2 120 ? 136.374 100.351 94.226  1.00 32.69  ? 66  TYR E N   1 
ATOM   3175  C  CA  A TYR B 2 120 ? 136.953 99.597  93.120  0.50 34.05  ? 66  TYR E CA  1 
ATOM   3176  C  CA  B TYR B 2 120 ? 136.959 99.585  93.137  0.50 34.13  ? 66  TYR E CA  1 
ATOM   3177  C  C   . TYR B 2 120 ? 135.837 98.998  92.292  1.00 32.59  ? 66  TYR E C   1 
ATOM   3178  O  O   . TYR B 2 120 ? 134.957 98.323  92.829  1.00 39.02  ? 66  TYR E O   1 
ATOM   3179  C  CB  A TYR B 2 120 ? 137.851 98.459  93.602  0.50 36.30  ? 66  TYR E CB  1 
ATOM   3180  C  CB  B TYR B 2 120 ? 137.843 98.499  93.752  0.50 36.55  ? 66  TYR E CB  1 
ATOM   3181  C  CG  A TYR B 2 120 ? 139.236 98.846  94.041  0.50 37.03  ? 66  TYR E CG  1 
ATOM   3182  C  CG  B TYR B 2 120 ? 138.596 97.570  92.842  0.50 38.03  ? 66  TYR E CG  1 
ATOM   3183  C  CD1 A TYR B 2 120 ? 139.492 99.201  95.356  0.50 36.75  ? 66  TYR E CD1 1 
ATOM   3184  C  CD1 B TYR B 2 120 ? 137.991 96.431  92.323  0.50 40.20  ? 66  TYR E CD1 1 
ATOM   3185  C  CD2 A TYR B 2 120 ? 140.296 98.822  93.150  0.50 37.56  ? 66  TYR E CD2 1 
ATOM   3186  C  CD2 B TYR B 2 120 ? 139.939 97.781  92.567  0.50 39.04  ? 66  TYR E CD2 1 
ATOM   3187  C  CE1 A TYR B 2 120 ? 140.754 99.540  95.766  0.50 36.74  ? 66  TYR E CE1 1 
ATOM   3188  C  CE1 B TYR B 2 120 ? 138.689 95.556  91.516  0.50 41.85  ? 66  TYR E CE1 1 
ATOM   3189  C  CE2 A TYR B 2 120 ? 141.565 99.161  93.552  0.50 39.87  ? 66  TYR E CE2 1 
ATOM   3190  C  CE2 B TYR B 2 120 ? 140.648 96.908  91.763  0.50 42.43  ? 66  TYR E CE2 1 
ATOM   3191  C  CZ  A TYR B 2 120 ? 141.789 99.515  94.862  0.50 40.22  ? 66  TYR E CZ  1 
ATOM   3192  C  CZ  B TYR B 2 120 ? 140.016 95.796  91.241  0.50 43.28  ? 66  TYR E CZ  1 
ATOM   3193  O  OH  A TYR B 2 120 ? 143.057 99.854  95.268  0.50 42.31  ? 66  TYR E OH  1 
ATOM   3194  O  OH  B TYR B 2 120 ? 140.710 94.923  90.435  0.50 40.86  ? 66  TYR E OH  1 
ATOM   3195  N  N   . TRP B 2 121 ? 135.869 99.233  90.984  1.00 30.42  ? 67  TRP E N   1 
ATOM   3196  C  CA  . TRP B 2 121 ? 134.872 98.595  90.128  1.00 28.13  ? 67  TRP E CA  1 
ATOM   3197  C  C   . TRP B 2 121 ? 135.439 98.441  88.727  1.00 31.31  ? 67  TRP E C   1 
ATOM   3198  O  O   . TRP B 2 121 ? 136.588 98.784  88.465  1.00 37.17  ? 67  TRP E O   1 
ATOM   3199  C  CB  . TRP B 2 121 ? 133.550 99.362  90.121  1.00 28.69  ? 67  TRP E CB  1 
ATOM   3200  C  CG  . TRP B 2 121 ? 133.593 100.662 89.423  1.00 30.28  ? 67  TRP E CG  1 
ATOM   3201  C  CD1 . TRP B 2 121 ? 133.337 100.894 88.110  1.00 28.48  ? 67  TRP E CD1 1 
ATOM   3202  C  CD2 . TRP B 2 121 ? 133.894 101.927 90.005  1.00 31.76  ? 67  TRP E CD2 1 
ATOM   3203  N  NE1 . TRP B 2 121 ? 133.469 102.225 87.834  1.00 29.29  ? 67  TRP E NE1 1 
ATOM   3204  C  CE2 . TRP B 2 121 ? 133.809 102.882 88.985  1.00 28.56  ? 67  TRP E CE2 1 
ATOM   3205  C  CE3 . TRP B 2 121 ? 134.225 102.344 91.292  1.00 30.11  ? 67  TRP E CE3 1 
ATOM   3206  C  CZ2 . TRP B 2 121 ? 134.047 104.224 89.209  1.00 23.57  ? 67  TRP E CZ2 1 
ATOM   3207  C  CZ3 . TRP B 2 121 ? 134.466 103.668 91.510  1.00 27.40  ? 67  TRP E CZ3 1 
ATOM   3208  C  CH2 . TRP B 2 121 ? 134.376 104.596 90.477  1.00 24.96  ? 67  TRP E CH2 1 
ATOM   3209  N  N   . ARG B 2 122 ? 134.629 97.896  87.824  1.00 33.15  ? 68  ARG E N   1 
ATOM   3210  C  CA  . ARG B 2 122 ? 135.069 97.622  86.464  1.00 31.81  ? 68  ARG E CA  1 
ATOM   3211  C  C   . ARG B 2 122 ? 134.107 98.245  85.471  1.00 36.66  ? 68  ARG E C   1 
ATOM   3212  O  O   . ARG B 2 122 ? 132.896 98.031  85.557  1.00 40.42  ? 68  ARG E O   1 
ATOM   3213  C  CB  . ARG B 2 122 ? 135.170 96.123  86.201  1.00 32.50  ? 68  ARG E CB  1 
ATOM   3214  C  CG  . ARG B 2 122 ? 135.740 95.808  84.840  1.00 39.58  ? 68  ARG E CG  1 
ATOM   3215  C  CD  . ARG B 2 122 ? 135.778 94.328  84.560  1.00 54.34  ? 68  ARG E CD  1 
ATOM   3216  N  NE  . ARG B 2 122 ? 136.379 94.075  83.258  1.00 74.37  ? 68  ARG E NE  1 
ATOM   3217  C  CZ  . ARG B 2 122 ? 136.211 92.966  82.552  1.00 81.74  ? 68  ARG E CZ  1 
ATOM   3218  N  NH1 . ARG B 2 122 ? 135.451 91.977  82.989  1.00 82.77  ? 68  ARG E NH1 1 
ATOM   3219  N  NH2 . ARG B 2 122 ? 136.816 92.851  81.374  1.00 77.94  ? 68  ARG E NH2 1 
ATOM   3220  N  N   . ASP B 2 123 ? 134.653 98.988  84.514  1.00 37.20  ? 69  ASP E N   1 
ATOM   3221  C  CA  . ASP B 2 123 ? 133.878 99.628  83.458  1.00 39.25  ? 69  ASP E CA  1 
ATOM   3222  C  C   . ASP B 2 123 ? 134.488 99.213  82.128  1.00 42.35  ? 69  ASP E C   1 
ATOM   3223  O  O   . ASP B 2 123 ? 135.632 99.567  81.833  1.00 47.86  ? 69  ASP E O   1 
ATOM   3224  C  CB  . ASP B 2 123 ? 133.891 101.146 83.620  1.00 39.12  ? 69  ASP E CB  1 
ATOM   3225  C  CG  . ASP B 2 123 ? 132.727 101.818 82.931  1.00 43.67  ? 69  ASP E CG  1 
ATOM   3226  O  OD1 . ASP B 2 123 ? 132.109 101.196 82.048  1.00 43.60  ? 69  ASP E OD1 1 
ATOM   3227  O  OD2 . ASP B 2 123 ? 132.435 102.981 83.268  1.00 46.09  ? 69  ASP E OD2 1 
ATOM   3228  N  N   . LYS B 2 124 ? 133.736 98.460  81.327  1.00 41.83  ? 70  LYS E N   1 
ATOM   3229  C  CA  . LYS B 2 124 ? 134.270 97.986  80.058  1.00 45.89  ? 70  LYS E CA  1 
ATOM   3230  C  C   . LYS B 2 124 ? 134.418 99.102  79.036  1.00 48.58  ? 70  LYS E C   1 
ATOM   3231  O  O   . LYS B 2 124 ? 135.138 98.927  78.049  1.00 52.23  ? 70  LYS E O   1 
ATOM   3232  C  CB  . LYS B 2 124 ? 133.385 96.876  79.497  1.00 53.30  ? 70  LYS E CB  1 
ATOM   3233  C  CG  . LYS B 2 124 ? 133.385 95.622  80.347  1.00 65.30  ? 70  LYS E CG  1 
ATOM   3234  C  CD  . LYS B 2 124 ? 132.300 94.658  79.914  1.00 69.35  ? 70  LYS E CD  1 
ATOM   3235  C  CE  . LYS B 2 124 ? 132.119 93.551  80.936  1.00 74.16  ? 70  LYS E CE  1 
ATOM   3236  N  NZ  . LYS B 2 124 ? 130.944 92.694  80.620  1.00 69.11  ? 70  LYS E NZ  1 
ATOM   3237  N  N   . ARG B 2 125 ? 133.763 100.243 79.250  1.00 47.13  ? 71  ARG E N   1 
ATOM   3238  C  CA  . ARG B 2 125 ? 133.895 101.367 78.332  1.00 48.81  ? 71  ARG E CA  1 
ATOM   3239  C  C   . ARG B 2 125 ? 135.236 102.072 78.452  1.00 50.85  ? 71  ARG E C   1 
ATOM   3240  O  O   . ARG B 2 125 ? 135.564 102.889 77.588  1.00 51.95  ? 71  ARG E O   1 
ATOM   3241  C  CB  . ARG B 2 125 ? 132.778 102.381 78.570  1.00 46.27  ? 71  ARG E CB  1 
ATOM   3242  C  CG  . ARG B 2 125 ? 131.384 101.849 78.351  1.00 46.40  ? 71  ARG E CG  1 
ATOM   3243  C  CD  . ARG B 2 125 ? 130.343 102.914 78.651  1.00 47.90  ? 71  ARG E CD  1 
ATOM   3244  N  NE  . ARG B 2 125 ? 130.161 103.140 80.080  1.00 48.51  ? 71  ARG E NE  1 
ATOM   3245  C  CZ  . ARG B 2 125 ? 129.338 104.045 80.592  1.00 46.39  ? 71  ARG E CZ  1 
ATOM   3246  N  NH1 . ARG B 2 125 ? 128.622 104.842 79.820  1.00 46.91  ? 71  ARG E NH1 1 
ATOM   3247  N  NH2 . ARG B 2 125 ? 129.233 104.154 81.911  1.00 43.72  ? 71  ARG E NH2 1 
ATOM   3248  N  N   . LEU B 2 126 ? 136.004 101.796 79.503  1.00 49.46  ? 72  LEU E N   1 
ATOM   3249  C  CA  . LEU B 2 126 ? 137.267 102.473 79.752  1.00 46.34  ? 72  LEU E CA  1 
ATOM   3250  C  C   . LEU B 2 126 ? 138.470 101.581 79.499  1.00 53.02  ? 72  LEU E C   1 
ATOM   3251  O  O   . LEU B 2 126 ? 139.591 101.959 79.847  1.00 59.19  ? 72  LEU E O   1 
ATOM   3252  C  CB  . LEU B 2 126 ? 137.309 103.000 81.186  1.00 45.16  ? 72  LEU E CB  1 
ATOM   3253  C  CG  . LEU B 2 126 ? 136.256 104.030 81.580  1.00 44.01  ? 72  LEU E CG  1 
ATOM   3254  C  CD1 . LEU B 2 126 ? 136.391 104.374 83.040  1.00 44.67  ? 72  LEU E CD1 1 
ATOM   3255  C  CD2 . LEU B 2 126 ? 136.392 105.266 80.733  1.00 46.26  ? 72  LEU E CD2 1 
ATOM   3256  N  N   . ALA B 2 127 ? 138.267 100.403 78.922  1.00 55.23  ? 73  ALA E N   1 
ATOM   3257  C  CA  . ALA B 2 127 ? 139.383 99.525  78.612  1.00 52.06  ? 73  ALA E CA  1 
ATOM   3258  C  C   . ALA B 2 127 ? 140.228 100.121 77.497  1.00 57.96  ? 73  ALA E C   1 
ATOM   3259  O  O   . ALA B 2 127 ? 139.704 100.634 76.506  1.00 62.28  ? 73  ALA E O   1 
ATOM   3260  C  CB  . ALA B 2 127 ? 138.875 98.144  78.210  1.00 49.29  ? 73  ALA E CB  1 
ATOM   3261  N  N   . TYR B 2 128 ? 141.544 100.051 77.662  1.00 53.99  ? 74  TYR E N   1 
ATOM   3262  C  CA  . TYR B 2 128 ? 142.475 100.538 76.658  1.00 56.25  ? 74  TYR E CA  1 
ATOM   3263  C  C   . TYR B 2 128 ? 143.588 99.520  76.479  1.00 65.05  ? 74  TYR E C   1 
ATOM   3264  O  O   . TYR B 2 128 ? 143.887 98.742  77.386  1.00 65.91  ? 74  TYR E O   1 
ATOM   3265  C  CB  . TYR B 2 128 ? 143.058 101.900 77.039  1.00 53.22  ? 74  TYR E CB  1 
ATOM   3266  C  CG  . TYR B 2 128 ? 143.791 101.903 78.355  1.00 55.76  ? 74  TYR E CG  1 
ATOM   3267  C  CD1 . TYR B 2 128 ? 143.123 102.145 79.543  1.00 54.05  ? 74  TYR E CD1 1 
ATOM   3268  C  CD2 . TYR B 2 128 ? 145.153 101.673 78.409  1.00 60.40  ? 74  TYR E CD2 1 
ATOM   3269  C  CE1 . TYR B 2 128 ? 143.791 102.151 80.743  1.00 53.37  ? 74  TYR E CE1 1 
ATOM   3270  C  CE2 . TYR B 2 128 ? 145.827 101.673 79.604  1.00 58.54  ? 74  TYR E CE2 1 
ATOM   3271  C  CZ  . TYR B 2 128 ? 145.142 101.912 80.767  1.00 55.42  ? 74  TYR E CZ  1 
ATOM   3272  O  OH  . TYR B 2 128 ? 145.818 101.914 81.959  1.00 56.38  ? 74  TYR E OH  1 
ATOM   3273  N  N   . SER B 2 129 ? 144.199 99.532  75.299  1.00 69.62  ? 75  SER E N   1 
ATOM   3274  C  CA  . SER B 2 129 ? 145.252 98.589  74.961  1.00 69.80  ? 75  SER E CA  1 
ATOM   3275  C  C   . SER B 2 129 ? 146.450 99.336  74.398  1.00 73.22  ? 75  SER E C   1 
ATOM   3276  O  O   . SER B 2 129 ? 146.337 100.468 73.923  1.00 74.15  ? 75  SER E O   1 
ATOM   3277  C  CB  . SER B 2 129 ? 144.769 97.541  73.954  1.00 68.52  ? 75  SER E CB  1 
ATOM   3278  O  OG  . SER B 2 129 ? 144.263 98.157  72.787  1.00 72.41  ? 75  SER E OG  1 
ATOM   3279  N  N   . GLY B 2 130 ? 147.611 98.688  74.471  1.00 73.51  ? 76  GLY E N   1 
ATOM   3280  C  CA  . GLY B 2 130 ? 148.841 99.250  73.967  1.00 76.16  ? 76  GLY E CA  1 
ATOM   3281  C  C   . GLY B 2 130 ? 149.614 100.094 74.953  1.00 78.55  ? 76  GLY E C   1 
ATOM   3282  O  O   . GLY B 2 130 ? 150.753 100.473 74.659  1.00 80.71  ? 76  GLY E O   1 
ATOM   3283  N  N   . ILE B 2 131 ? 149.040 100.396 76.109  1.00 76.62  ? 77  ILE E N   1 
ATOM   3284  C  CA  . ILE B 2 131 ? 149.690 101.187 77.142  1.00 72.79  ? 77  ILE E CA  1 
ATOM   3285  C  C   . ILE B 2 131 ? 149.860 100.308 78.374  1.00 76.83  ? 77  ILE E C   1 
ATOM   3286  O  O   . ILE B 2 131 ? 148.903 100.050 79.103  1.00 78.28  ? 77  ILE E O   1 
ATOM   3287  C  CB  . ILE B 2 131 ? 148.882 102.453 77.473  1.00 69.82  ? 77  ILE E CB  1 
ATOM   3288  C  CG1 . ILE B 2 131 ? 148.789 103.352 76.243  1.00 68.37  ? 77  ILE E CG1 1 
ATOM   3289  C  CG2 . ILE B 2 131 ? 149.510 103.194 78.633  1.00 67.74  ? 77  ILE E CG2 1 
ATOM   3290  C  CD1 . ILE B 2 131 ? 147.954 104.587 76.457  1.00 68.12  ? 77  ILE E CD1 1 
ATOM   3291  N  N   . PRO B 2 132 ? 151.059 99.819  78.631  1.00 77.02  ? 78  PRO E N   1 
ATOM   3292  C  CA  . PRO B 2 132 ? 151.303 98.947  79.787  1.00 75.65  ? 78  PRO E CA  1 
ATOM   3293  C  C   . PRO B 2 132 ? 151.479 99.709  81.099  1.00 74.29  ? 78  PRO E C   1 
ATOM   3294  O  O   . PRO B 2 132 ? 152.446 99.503  81.834  1.00 77.05  ? 78  PRO E O   1 
ATOM   3295  C  CB  . PRO B 2 132 ? 152.582 98.209  79.384  1.00 76.30  ? 78  PRO E CB  1 
ATOM   3296  C  CG  . PRO B 2 132 ? 153.312 99.194  78.546  1.00 79.43  ? 78  PRO E CG  1 
ATOM   3297  C  CD  . PRO B 2 132 ? 152.262 99.974  77.795  1.00 75.19  ? 78  PRO E CD  1 
ATOM   3298  N  N   . LEU B 2 133 ? 150.530 100.597 81.397  1.00 70.09  ? 79  LEU E N   1 
ATOM   3299  C  CA  . LEU B 2 133 ? 150.594 101.435 82.585  1.00 65.57  ? 79  LEU E CA  1 
ATOM   3300  C  C   . LEU B 2 133 ? 149.211 101.576 83.199  1.00 63.11  ? 79  LEU E C   1 
ATOM   3301  O  O   . LEU B 2 133 ? 148.196 101.519 82.503  1.00 66.11  ? 79  LEU E O   1 
ATOM   3302  C  CB  . LEU B 2 133 ? 151.146 102.827 82.265  1.00 64.07  ? 79  LEU E CB  1 
ATOM   3303  C  CG  . LEU B 2 133 ? 152.606 102.920 81.829  1.00 68.03  ? 79  LEU E CG  1 
ATOM   3304  C  CD1 . LEU B 2 133 ? 152.895 104.292 81.256  1.00 64.27  ? 79  LEU E CD1 1 
ATOM   3305  C  CD2 . LEU B 2 133 ? 153.521 102.631 83.002  1.00 71.21  ? 79  LEU E CD2 1 
ATOM   3306  N  N   . ASN B 2 134 ? 149.184 101.767 84.513  1.00 59.38  ? 80  ASN E N   1 
ATOM   3307  C  CA  . ASN B 2 134 ? 147.959 102.092 85.232  1.00 58.24  ? 80  ASN E CA  1 
ATOM   3308  C  C   . ASN B 2 134 ? 147.845 103.610 85.296  1.00 56.05  ? 80  ASN E C   1 
ATOM   3309  O  O   . ASN B 2 134 ? 148.538 104.256 86.085  1.00 60.93  ? 80  ASN E O   1 
ATOM   3310  C  CB  . ASN B 2 134 ? 147.975 101.476 86.627  1.00 56.40  ? 80  ASN E CB  1 
ATOM   3311  C  CG  . ASN B 2 134 ? 148.006 99.969  86.593  1.00 60.69  ? 80  ASN E CG  1 
ATOM   3312  O  OD1 . ASN B 2 134 ? 147.535 99.355  85.645  1.00 62.14  ? 80  ASN E OD1 1 
ATOM   3313  N  ND2 . ASN B 2 134 ? 148.565 99.364  87.627  1.00 65.36  ? 80  ASN E ND2 1 
ATOM   3314  N  N   . LEU B 2 135 ? 146.969 104.179 84.477  1.00 46.59  ? 81  LEU E N   1 
ATOM   3315  C  CA  . LEU B 2 135 ? 146.962 105.622 84.261  1.00 43.15  ? 81  LEU E CA  1 
ATOM   3316  C  C   . LEU B 2 135 ? 146.326 106.323 85.451  1.00 43.20  ? 81  LEU E C   1 
ATOM   3317  O  O   . LEU B 2 135 ? 145.112 106.253 85.645  1.00 46.46  ? 81  LEU E O   1 
ATOM   3318  C  CB  . LEU B 2 135 ? 146.219 105.966 82.976  1.00 44.27  ? 81  LEU E CB  1 
ATOM   3319  C  CG  . LEU B 2 135 ? 146.775 105.359 81.695  1.00 51.19  ? 81  LEU E CG  1 
ATOM   3320  C  CD1 . LEU B 2 135 ? 145.979 105.830 80.502  1.00 52.37  ? 81  LEU E CD1 1 
ATOM   3321  C  CD2 . LEU B 2 135 ? 148.239 105.712 81.541  1.00 55.18  ? 81  LEU E CD2 1 
ATOM   3322  N  N   . THR B 2 136 ? 147.142 106.998 86.250  1.00 41.28  ? 82  THR E N   1 
ATOM   3323  C  CA  . THR B 2 136 ? 146.617 107.905 87.255  1.00 38.53  ? 82  THR E CA  1 
ATOM   3324  C  C   . THR B 2 136 ? 146.309 109.234 86.590  1.00 39.72  ? 82  THR E C   1 
ATOM   3325  O  O   . THR B 2 136 ? 147.169 109.810 85.919  1.00 42.13  ? 82  THR E O   1 
ATOM   3326  C  CB  . THR B 2 136 ? 147.614 108.115 88.387  1.00 40.80  ? 82  THR E CB  1 
ATOM   3327  O  OG1 . THR B 2 136 ? 147.854 106.877 89.062  1.00 48.82  ? 82  THR E OG1 1 
ATOM   3328  C  CG2 . THR B 2 136 ? 147.066 109.114 89.370  1.00 38.10  ? 82  THR E CG2 1 
ATOM   3329  N  N   . LEU B 2 137 ? 145.083 109.715 86.754  1.00 40.21  ? 83  LEU E N   1 
ATOM   3330  C  CA  . LEU B 2 137 ? 144.682 110.938 86.081  1.00 39.34  ? 83  LEU E CA  1 
ATOM   3331  C  C   . LEU B 2 137 ? 144.387 112.027 87.099  1.00 44.79  ? 83  LEU E C   1 
ATOM   3332  O  O   . LEU B 2 137 ? 144.188 111.760 88.286  1.00 47.26  ? 83  LEU E O   1 
ATOM   3333  C  CB  . LEU B 2 137 ? 143.468 110.699 85.182  1.00 36.24  ? 83  LEU E CB  1 
ATOM   3334  C  CG  . LEU B 2 137 ? 143.748 109.743 84.025  1.00 36.42  ? 83  LEU E CG  1 
ATOM   3335  C  CD1 . LEU B 2 137 ? 142.476 109.404 83.294  1.00 39.03  ? 83  LEU E CD1 1 
ATOM   3336  C  CD2 . LEU B 2 137 ? 144.759 110.353 83.079  1.00 35.11  ? 83  LEU E CD2 1 
ATOM   3337  N  N   . ASP B 2 138 ? 144.388 113.268 86.620  1.00 40.99  ? 84  ASP E N   1 
ATOM   3338  C  CA  . ASP B 2 138 ? 144.023 114.394 87.464  1.00 44.79  ? 84  ASP E CA  1 
ATOM   3339  C  C   . ASP B 2 138 ? 142.624 114.177 88.018  1.00 47.36  ? 84  ASP E C   1 
ATOM   3340  O  O   . ASP B 2 138 ? 141.722 113.734 87.305  1.00 47.84  ? 84  ASP E O   1 
ATOM   3341  C  CB  . ASP B 2 138 ? 144.090 115.696 86.666  1.00 43.21  ? 84  ASP E CB  1 
ATOM   3342  C  CG  . ASP B 2 138 ? 144.060 116.935 87.548  1.00 56.93  ? 84  ASP E CG  1 
ATOM   3343  O  OD1 . ASP B 2 138 ? 143.142 117.068 88.380  1.00 62.23  ? 84  ASP E OD1 1 
ATOM   3344  O  OD2 . ASP B 2 138 ? 144.963 117.784 87.410  1.00 61.23  ? 84  ASP E OD2 1 
ATOM   3345  N  N   . ASN B 2 139 ? 142.446 114.490 89.302  1.00 46.72  ? 85  ASN E N   1 
ATOM   3346  C  CA  . ASN B 2 139 ? 141.195 114.166 89.973  1.00 44.02  ? 85  ASN E CA  1 
ATOM   3347  C  C   . ASN B 2 139 ? 139.993 114.828 89.316  1.00 46.68  ? 85  ASN E C   1 
ATOM   3348  O  O   . ASN B 2 139 ? 138.872 114.336 89.472  1.00 51.54  ? 85  ASN E O   1 
ATOM   3349  C  CB  . ASN B 2 139 ? 141.272 114.555 91.449  1.00 42.89  ? 85  ASN E CB  1 
ATOM   3350  C  CG  . ASN B 2 139 ? 141.477 116.035 91.655  1.00 45.75  ? 85  ASN E CG  1 
ATOM   3351  O  OD1 . ASN B 2 139 ? 140.521 116.798 91.754  1.00 48.22  ? 85  ASN E OD1 1 
ATOM   3352  N  ND2 . ASN B 2 139 ? 142.731 116.450 91.730  1.00 47.95  ? 85  ASN E ND2 1 
ATOM   3353  N  N   . ARG B 2 140 ? 140.193 115.915 88.571  1.00 45.04  ? 86  ARG E N   1 
ATOM   3354  C  CA  . ARG B 2 140 ? 139.067 116.568 87.918  1.00 47.12  ? 86  ARG E CA  1 
ATOM   3355  C  C   . ARG B 2 140 ? 138.425 115.690 86.855  1.00 48.89  ? 86  ARG E C   1 
ATOM   3356  O  O   . ARG B 2 140 ? 137.246 115.884 86.541  1.00 53.39  ? 86  ARG E O   1 
ATOM   3357  C  CB  . ARG B 2 140 ? 139.513 117.895 87.315  1.00 50.75  ? 86  ARG E CB  1 
ATOM   3358  C  CG  . ARG B 2 140 ? 139.987 118.882 88.360  1.00 53.59  ? 86  ARG E CG  1 
ATOM   3359  C  CD  . ARG B 2 140 ? 140.168 120.274 87.798  1.00 57.77  ? 86  ARG E CD  1 
ATOM   3360  N  NE  . ARG B 2 140 ? 141.344 120.386 86.946  1.00 59.27  ? 86  ARG E NE  1 
ATOM   3361  C  CZ  . ARG B 2 140 ? 141.744 121.516 86.384  1.00 61.55  ? 86  ARG E CZ  1 
ATOM   3362  N  NH1 . ARG B 2 140 ? 141.087 122.648 86.568  1.00 63.97  ? 86  ARG E NH1 1 
ATOM   3363  N  NH2 . ARG B 2 140 ? 142.829 121.511 85.616  1.00 59.62  ? 86  ARG E NH2 1 
ATOM   3364  N  N   . VAL B 2 141 ? 139.155 114.715 86.311  1.00 46.52  ? 87  VAL E N   1 
ATOM   3365  C  CA  . VAL B 2 141 ? 138.564 113.760 85.388  1.00 41.56  ? 87  VAL E CA  1 
ATOM   3366  C  C   . VAL B 2 141 ? 137.483 112.925 86.051  1.00 46.02  ? 87  VAL E C   1 
ATOM   3367  O  O   . VAL B 2 141 ? 136.714 112.259 85.359  1.00 51.61  ? 87  VAL E O   1 
ATOM   3368  C  CB  . VAL B 2 141 ? 139.640 112.838 84.775  1.00 36.57  ? 87  VAL E CB  1 
ATOM   3369  C  CG1 . VAL B 2 141 ? 139.905 111.659 85.671  1.00 37.70  ? 87  VAL E CG1 1 
ATOM   3370  C  CG2 . VAL B 2 141 ? 139.209 112.356 83.412  1.00 40.73  ? 87  VAL E CG2 1 
ATOM   3371  N  N   . ALA B 2 142 ? 137.402 112.948 87.381  1.00 46.03  ? 88  ALA E N   1 
ATOM   3372  C  CA  . ALA B 2 142 ? 136.298 112.293 88.065  1.00 42.47  ? 88  ALA E CA  1 
ATOM   3373  C  C   . ALA B 2 142 ? 134.961 112.935 87.738  1.00 46.37  ? 88  ALA E C   1 
ATOM   3374  O  O   . ALA B 2 142 ? 133.921 112.302 87.932  1.00 51.24  ? 88  ALA E O   1 
ATOM   3375  C  CB  . ALA B 2 142 ? 136.526 112.317 89.574  1.00 38.36  ? 88  ALA E CB  1 
ATOM   3376  N  N   . ASP B 2 143 ? 134.961 114.174 87.249  1.00 52.15  ? 89  ASP E N   1 
ATOM   3377  C  CA  . ASP B 2 143 ? 133.719 114.839 86.883  1.00 55.76  ? 89  ASP E CA  1 
ATOM   3378  C  C   . ASP B 2 143 ? 133.170 114.381 85.542  1.00 53.67  ? 89  ASP E C   1 
ATOM   3379  O  O   . ASP B 2 143 ? 132.034 114.728 85.209  1.00 59.35  ? 89  ASP E O   1 
ATOM   3380  C  CB  . ASP B 2 143 ? 133.921 116.353 86.847  1.00 61.81  ? 89  ASP E CB  1 
ATOM   3381  C  CG  . ASP B 2 143 ? 134.285 116.925 88.198  1.00 70.02  ? 89  ASP E CG  1 
ATOM   3382  O  OD1 . ASP B 2 143 ? 133.707 116.480 89.209  1.00 73.16  ? 89  ASP E OD1 1 
ATOM   3383  O  OD2 . ASP B 2 143 ? 135.148 117.825 88.249  1.00 67.43  ? 89  ASP E OD2 1 
ATOM   3384  N  N   . GLN B 2 144 ? 133.946 113.629 84.764  1.00 48.26  ? 90  GLN E N   1 
ATOM   3385  C  CA  . GLN B 2 144 ? 133.524 113.159 83.454  1.00 48.24  ? 90  GLN E CA  1 
ATOM   3386  C  C   . GLN B 2 144 ? 133.270 111.661 83.430  1.00 47.27  ? 90  GLN E C   1 
ATOM   3387  O  O   . GLN B 2 144 ? 133.073 111.093 82.354  1.00 50.52  ? 90  GLN E O   1 
ATOM   3388  C  CB  . GLN B 2 144 ? 134.571 113.515 82.400  1.00 50.42  ? 90  GLN E CB  1 
ATOM   3389  C  CG  . GLN B 2 144 ? 135.202 114.874 82.574  1.00 55.11  ? 90  GLN E CG  1 
ATOM   3390  C  CD  . GLN B 2 144 ? 136.324 115.109 81.587  1.00 70.32  ? 90  GLN E CD  1 
ATOM   3391  O  OE1 . GLN B 2 144 ? 136.325 114.554 80.488  1.00 75.15  ? 90  GLN E OE1 1 
ATOM   3392  N  NE2 . GLN B 2 144 ? 137.294 115.929 81.976  1.00 63.66  ? 90  GLN E NE2 1 
ATOM   3393  N  N   . LEU B 2 145 ? 133.275 111.010 84.585  1.00 44.64  ? 91  LEU E N   1 
ATOM   3394  C  CA  . LEU B 2 145 ? 133.133 109.569 84.674  1.00 43.24  ? 91  LEU E CA  1 
ATOM   3395  C  C   . LEU B 2 145 ? 131.984 109.233 85.606  1.00 43.76  ? 91  LEU E C   1 
ATOM   3396  O  O   . LEU B 2 145 ? 131.613 110.022 86.476  1.00 47.03  ? 91  LEU E O   1 
ATOM   3397  C  CB  . LEU B 2 145 ? 134.415 108.910 85.184  1.00 40.03  ? 91  LEU E CB  1 
ATOM   3398  C  CG  . LEU B 2 145 ? 135.646 109.112 84.315  1.00 43.00  ? 91  LEU E CG  1 
ATOM   3399  C  CD1 . LEU B 2 145 ? 136.868 108.602 85.032  1.00 42.12  ? 91  LEU E CD1 1 
ATOM   3400  C  CD2 . LEU B 2 145 ? 135.461 108.394 83.007  1.00 40.78  ? 91  LEU E CD2 1 
ATOM   3401  N  N   . TRP B 2 146 ? 131.416 108.051 85.412  1.00 38.73  ? 92  TRP E N   1 
ATOM   3402  C  CA  . TRP B 2 146 ? 130.421 107.541 86.338  1.00 34.62  ? 92  TRP E CA  1 
ATOM   3403  C  C   . TRP B 2 146 ? 131.115 107.053 87.599  1.00 34.87  ? 92  TRP E C   1 
ATOM   3404  O  O   . TRP B 2 146 ? 132.118 106.339 87.526  1.00 40.42  ? 92  TRP E O   1 
ATOM   3405  C  CB  . TRP B 2 146 ? 129.620 106.410 85.699  1.00 34.28  ? 92  TRP E CB  1 
ATOM   3406  C  CG  . TRP B 2 146 ? 128.597 105.812 86.611  1.00 35.42  ? 92  TRP E CG  1 
ATOM   3407  C  CD1 . TRP B 2 146 ? 127.285 106.152 86.694  1.00 35.43  ? 92  TRP E CD1 1 
ATOM   3408  C  CD2 . TRP B 2 146 ? 128.805 104.775 87.574  1.00 35.92  ? 92  TRP E CD2 1 
ATOM   3409  N  NE1 . TRP B 2 146 ? 126.661 105.393 87.645  1.00 34.69  ? 92  TRP E NE1 1 
ATOM   3410  C  CE2 . TRP B 2 146 ? 127.574 104.538 88.198  1.00 38.95  ? 92  TRP E CE2 1 
ATOM   3411  C  CE3 . TRP B 2 146 ? 129.914 104.023 87.967  1.00 32.78  ? 92  TRP E CE3 1 
ATOM   3412  C  CZ2 . TRP B 2 146 ? 127.420 103.584 89.192  1.00 39.11  ? 92  TRP E CZ2 1 
ATOM   3413  C  CZ3 . TRP B 2 146 ? 129.756 103.077 88.950  1.00 30.53  ? 92  TRP E CZ3 1 
ATOM   3414  C  CH2 . TRP B 2 146 ? 128.521 102.865 89.551  1.00 34.29  ? 92  TRP E CH2 1 
ATOM   3415  N  N   . VAL B 2 147 ? 130.590 107.446 88.754  1.00 33.65  ? 93  VAL E N   1 
ATOM   3416  C  CA  . VAL B 2 147 ? 131.083 106.945 90.032  1.00 32.87  ? 93  VAL E CA  1 
ATOM   3417  C  C   . VAL B 2 147 ? 129.877 106.537 90.868  1.00 34.51  ? 93  VAL E C   1 
ATOM   3418  O  O   . VAL B 2 147 ? 128.780 107.074 90.667  1.00 31.42  ? 93  VAL E O   1 
ATOM   3419  C  CB  . VAL B 2 147 ? 131.953 107.989 90.749  1.00 27.12  ? 93  VAL E CB  1 
ATOM   3420  C  CG1 . VAL B 2 147 ? 133.265 108.170 90.022  1.00 26.51  ? 93  VAL E CG1 1 
ATOM   3421  C  CG2 . VAL B 2 147 ? 131.232 109.306 90.843  1.00 31.73  ? 93  VAL E CG2 1 
ATOM   3422  N  N   . PRO B 2 148 ? 130.018 105.579 91.782  1.00 35.38  ? 94  PRO E N   1 
ATOM   3423  C  CA  . PRO B 2 148 ? 128.876 105.173 92.605  1.00 32.76  ? 94  PRO E CA  1 
ATOM   3424  C  C   . PRO B 2 148 ? 128.408 106.287 93.526  1.00 34.35  ? 94  PRO E C   1 
ATOM   3425  O  O   . PRO B 2 148 ? 129.199 107.088 94.027  1.00 36.53  ? 94  PRO E O   1 
ATOM   3426  C  CB  . PRO B 2 148 ? 129.423 103.990 93.408  1.00 32.02  ? 94  PRO E CB  1 
ATOM   3427  C  CG  . PRO B 2 148 ? 130.635 103.554 92.691  1.00 29.60  ? 94  PRO E CG  1 
ATOM   3428  C  CD  . PRO B 2 148 ? 131.206 104.759 92.051  1.00 31.87  ? 94  PRO E CD  1 
ATOM   3429  N  N   . ASP B 2 149 ? 127.099 106.313 93.766  1.00 32.23  ? 95  ASP E N   1 
ATOM   3430  C  CA  . ASP B 2 149 ? 126.487 107.313 94.640  1.00 34.05  ? 95  ASP E CA  1 
ATOM   3431  C  C   . ASP B 2 149 ? 126.433 106.808 96.082  1.00 34.19  ? 95  ASP E C   1 
ATOM   3432  O  O   . ASP B 2 149 ? 125.386 106.735 96.714  1.00 35.48  ? 95  ASP E O   1 
ATOM   3433  C  CB  . ASP B 2 149 ? 125.101 107.685 94.130  1.00 37.60  ? 95  ASP E CB  1 
ATOM   3434  C  CG  . ASP B 2 149 ? 124.211 106.483 93.941  1.00 39.32  ? 95  ASP E CG  1 
ATOM   3435  O  OD1 . ASP B 2 149 ? 124.671 105.354 94.196  1.00 35.70  ? 95  ASP E OD1 1 
ATOM   3436  O  OD2 . ASP B 2 149 ? 123.049 106.665 93.533  1.00 43.17  ? 95  ASP E OD2 1 
ATOM   3437  N  N   . THR B 2 150 ? 127.604 106.457 96.591  1.00 32.66  ? 96  THR E N   1 
ATOM   3438  C  CA  . THR B 2 150 ? 127.714 105.952 97.948  1.00 28.45  ? 96  THR E CA  1 
ATOM   3439  C  C   . THR B 2 150 ? 127.512 107.076 98.954  1.00 30.72  ? 96  THR E C   1 
ATOM   3440  O  O   . THR B 2 150 ? 128.073 108.163 98.808  1.00 39.65  ? 96  THR E O   1 
ATOM   3441  C  CB  . THR B 2 150 ? 129.076 105.300 98.136  1.00 30.16  ? 96  THR E CB  1 
ATOM   3442  O  OG1 . THR B 2 150 ? 129.077 104.023 97.496  1.00 30.46  ? 96  THR E OG1 1 
ATOM   3443  C  CG2 . THR B 2 150 ? 129.387 105.123 99.591  1.00 35.29  ? 96  THR E CG2 1 
ATOM   3444  N  N   . TYR B 2 151 ? 126.699 106.817 99.973  1.00 25.60  ? 97  TYR E N   1 
ATOM   3445  C  CA  . TYR B 2 151 ? 126.443 107.787 101.022 1.00 28.44  ? 97  TYR E CA  1 
ATOM   3446  C  C   . TYR B 2 151 ? 126.469 107.074 102.362 1.00 29.62  ? 97  TYR E C   1 
ATOM   3447  O  O   . TYR B 2 151 ? 126.473 105.843 102.438 1.00 31.09  ? 97  TYR E O   1 
ATOM   3448  C  CB  . TYR B 2 151 ? 125.105 108.509 100.812 1.00 29.38  ? 97  TYR E CB  1 
ATOM   3449  C  CG  . TYR B 2 151 ? 123.883 107.707 101.186 1.00 30.08  ? 97  TYR E CG  1 
ATOM   3450  C  CD1 . TYR B 2 151 ? 123.470 106.639 100.413 1.00 30.94  ? 97  TYR E CD1 1 
ATOM   3451  C  CD2 . TYR B 2 151 ? 123.130 108.033 102.299 1.00 29.03  ? 97  TYR E CD2 1 
ATOM   3452  C  CE1 . TYR B 2 151 ? 122.360 105.913 100.744 1.00 29.81  ? 97  TYR E CE1 1 
ATOM   3453  C  CE2 . TYR B 2 151 ? 122.017 107.311 102.636 1.00 27.88  ? 97  TYR E CE2 1 
ATOM   3454  C  CZ  . TYR B 2 151 ? 121.636 106.253 101.853 1.00 31.05  ? 97  TYR E CZ  1 
ATOM   3455  O  OH  . TYR B 2 151 ? 120.523 105.525 102.186 1.00 37.84  ? 97  TYR E OH  1 
ATOM   3456  N  N   . PHE B 2 152 ? 126.501 107.864 103.427 1.00 30.03  ? 98  PHE E N   1 
ATOM   3457  C  CA  . PHE B 2 152 ? 126.479 107.350 104.788 1.00 31.52  ? 98  PHE E CA  1 
ATOM   3458  C  C   . PHE B 2 152 ? 125.144 107.715 105.413 1.00 36.55  ? 98  PHE E C   1 
ATOM   3459  O  O   . PHE B 2 152 ? 124.788 108.893 105.471 1.00 42.84  ? 98  PHE E O   1 
ATOM   3460  C  CB  . PHE B 2 152 ? 127.637 107.915 105.606 1.00 32.77  ? 98  PHE E CB  1 
ATOM   3461  C  CG  . PHE B 2 152 ? 128.957 107.874 104.896 1.00 38.49  ? 98  PHE E CG  1 
ATOM   3462  C  CD1 . PHE B 2 152 ? 129.483 106.680 104.447 1.00 36.69  ? 98  PHE E CD1 1 
ATOM   3463  C  CD2 . PHE B 2 152 ? 129.676 109.030 104.683 1.00 37.01  ? 98  PHE E CD2 1 
ATOM   3464  C  CE1 . PHE B 2 152 ? 130.688 106.645 103.797 1.00 30.06  ? 98  PHE E CE1 1 
ATOM   3465  C  CE2 . PHE B 2 152 ? 130.881 108.994 104.035 1.00 33.81  ? 98  PHE E CE2 1 
ATOM   3466  C  CZ  . PHE B 2 152 ? 131.387 107.802 103.592 1.00 29.45  ? 98  PHE E CZ  1 
ATOM   3467  N  N   . LEU B 2 153 ? 124.412 106.706 105.884 1.00 32.29  ? 99  LEU E N   1 
ATOM   3468  C  CA  . LEU B 2 153 ? 123.049 106.940 106.345 1.00 30.89  ? 99  LEU E CA  1 
ATOM   3469  C  C   . LEU B 2 153 ? 123.010 107.719 107.650 1.00 32.90  ? 99  LEU E C   1 
ATOM   3470  O  O   . LEU B 2 153 ? 122.082 108.505 107.870 1.00 41.54  ? 99  LEU E O   1 
ATOM   3471  C  CB  . LEU B 2 153 ? 122.316 105.611 106.503 1.00 35.01  ? 99  LEU E CB  1 
ATOM   3472  C  CG  . LEU B 2 153 ? 120.876 105.686 107.002 1.00 36.43  ? 99  LEU E CG  1 
ATOM   3473  C  CD1 . LEU B 2 153 ? 120.053 106.625 106.147 1.00 32.45  ? 99  LEU E CD1 1 
ATOM   3474  C  CD2 . LEU B 2 153 ? 120.256 104.313 107.019 1.00 43.09  ? 99  LEU E CD2 1 
ATOM   3475  N  N   . ASN B 2 154 ? 123.993 107.523 108.526 1.00 31.02  ? 100 ASN E N   1 
ATOM   3476  C  CA  . ASN B 2 154 ? 123.942 108.078 109.870 1.00 30.84  ? 100 ASN E CA  1 
ATOM   3477  C  C   . ASN B 2 154 ? 124.887 109.254 110.062 1.00 32.20  ? 100 ASN E C   1 
ATOM   3478  O  O   . ASN B 2 154 ? 125.232 109.579 111.200 1.00 34.03  ? 100 ASN E O   1 
ATOM   3479  C  CB  . ASN B 2 154 ? 124.245 106.992 110.900 1.00 30.66  ? 100 ASN E CB  1 
ATOM   3480  C  CG  . ASN B 2 154 ? 125.671 106.518 110.835 1.00 32.99  ? 100 ASN E CG  1 
ATOM   3481  O  OD1 . ASN B 2 154 ? 126.202 106.267 109.760 1.00 40.12  ? 100 ASN E OD1 1 
ATOM   3482  N  ND2 . ASN B 2 154 ? 126.305 106.397 111.986 1.00 30.07  ? 100 ASN E ND2 1 
ATOM   3483  N  N   . ASP B 2 155 ? 125.308 109.909 108.988 1.00 33.15  ? 101 ASP E N   1 
ATOM   3484  C  CA  . ASP B 2 155 ? 126.246 111.014 109.115 1.00 33.18  ? 101 ASP E CA  1 
ATOM   3485  C  C   . ASP B 2 155 ? 125.505 112.344 109.171 1.00 37.25  ? 101 ASP E C   1 
ATOM   3486  O  O   . ASP B 2 155 ? 124.539 112.571 108.441 1.00 41.04  ? 101 ASP E O   1 
ATOM   3487  C  CB  . ASP B 2 155 ? 127.263 111.003 107.974 1.00 34.02  ? 101 ASP E CB  1 
ATOM   3488  C  CG  . ASP B 2 155 ? 126.771 111.702 106.737 1.00 43.81  ? 101 ASP E CG  1 
ATOM   3489  O  OD1 . ASP B 2 155 ? 125.638 111.433 106.301 1.00 55.91  ? 101 ASP E OD1 1 
ATOM   3490  O  OD2 . ASP B 2 155 ? 127.530 112.526 106.188 1.00 43.36  ? 101 ASP E OD2 1 
ATOM   3491  N  N   . LYS B 2 156 ? 125.950 113.209 110.076 1.00 35.63  ? 102 LYS E N   1 
ATOM   3492  C  CA  . LYS B 2 156 ? 125.354 114.520 110.263 1.00 31.69  ? 102 LYS E CA  1 
ATOM   3493  C  C   . LYS B 2 156 ? 126.072 115.599 109.474 1.00 34.51  ? 102 LYS E C   1 
ATOM   3494  O  O   . LYS B 2 156 ? 125.444 116.581 109.069 1.00 45.09  ? 102 LYS E O   1 
ATOM   3495  C  CB  . LYS B 2 156 ? 125.364 114.886 111.749 1.00 31.15  ? 102 LYS E CB  1 
ATOM   3496  C  CG  . LYS B 2 156 ? 124.820 113.805 112.650 1.00 32.79  ? 102 LYS E CG  1 
ATOM   3497  C  CD  . LYS B 2 156 ? 125.231 114.013 114.085 1.00 34.35  ? 102 LYS E CD  1 
ATOM   3498  C  CE  . LYS B 2 156 ? 124.587 115.233 114.685 1.00 38.40  ? 102 LYS E CE  1 
ATOM   3499  N  NZ  . LYS B 2 156 ? 124.864 115.319 116.141 1.00 37.31  ? 102 LYS E NZ  1 
ATOM   3500  N  N   . LYS B 2 157 ? 127.369 115.436 109.237 1.00 33.10  ? 103 LYS E N   1 
ATOM   3501  C  CA  . LYS B 2 157 ? 128.162 116.479 108.597 1.00 35.78  ? 103 LYS E CA  1 
ATOM   3502  C  C   . LYS B 2 157 ? 129.453 115.862 108.092 1.00 40.78  ? 103 LYS E C   1 
ATOM   3503  O  O   . LYS B 2 157 ? 130.221 115.307 108.881 1.00 43.57  ? 103 LYS E O   1 
ATOM   3504  C  CB  . LYS B 2 157 ? 128.439 117.606 109.579 1.00 34.20  ? 103 LYS E CB  1 
ATOM   3505  C  CG  . LYS B 2 157 ? 129.420 118.638 109.103 1.00 42.19  ? 103 LYS E CG  1 
ATOM   3506  C  CD  . LYS B 2 157 ? 129.220 119.947 109.847 1.00 52.62  ? 103 LYS E CD  1 
ATOM   3507  C  CE  . LYS B 2 157 ? 128.929 119.720 111.325 1.00 58.51  ? 103 LYS E CE  1 
ATOM   3508  N  NZ  . LYS B 2 157 ? 130.033 119.037 112.052 1.00 57.61  ? 103 LYS E NZ  1 
ATOM   3509  N  N   . SER B 2 158 ? 129.693 115.959 106.788 1.00 36.74  ? 104 SER E N   1 
ATOM   3510  C  CA  . SER B 2 158 ? 130.861 115.366 106.159 1.00 29.77  ? 104 SER E CA  1 
ATOM   3511  C  C   . SER B 2 158 ? 131.454 116.357 105.174 1.00 33.04  ? 104 SER E C   1 
ATOM   3512  O  O   . SER B 2 158 ? 130.775 117.263 104.693 1.00 43.50  ? 104 SER E O   1 
ATOM   3513  C  CB  . SER B 2 158 ? 130.511 114.069 105.428 1.00 35.02  ? 104 SER E CB  1 
ATOM   3514  O  OG  . SER B 2 158 ? 129.703 113.236 106.234 1.00 42.07  ? 104 SER E OG  1 
ATOM   3515  N  N   . PHE B 2 159 ? 132.736 116.174 104.875 1.00 27.85  ? 105 PHE E N   1 
ATOM   3516  C  CA  . PHE B 2 159 ? 133.372 116.945 103.819 1.00 26.16  ? 105 PHE E CA  1 
ATOM   3517  C  C   . PHE B 2 159 ? 134.575 116.179 103.297 1.00 27.37  ? 105 PHE E C   1 
ATOM   3518  O  O   . PHE B 2 159 ? 135.131 115.318 103.979 1.00 29.81  ? 105 PHE E O   1 
ATOM   3519  C  CB  . PHE B 2 159 ? 133.782 118.341 104.301 1.00 27.71  ? 105 PHE E CB  1 
ATOM   3520  C  CG  . PHE B 2 159 ? 134.803 118.339 105.402 1.00 27.75  ? 105 PHE E CG  1 
ATOM   3521  C  CD1 . PHE B 2 159 ? 134.420 118.181 106.719 1.00 27.86  ? 105 PHE E CD1 1 
ATOM   3522  C  CD2 . PHE B 2 159 ? 136.141 118.524 105.123 1.00 24.29  ? 105 PHE E CD2 1 
ATOM   3523  C  CE1 . PHE B 2 159 ? 135.351 118.187 107.727 1.00 25.31  ? 105 PHE E CE1 1 
ATOM   3524  C  CE2 . PHE B 2 159 ? 137.074 118.529 106.130 1.00 25.87  ? 105 PHE E CE2 1 
ATOM   3525  C  CZ  . PHE B 2 159 ? 136.677 118.361 107.432 1.00 26.06  ? 105 PHE E CZ  1 
ATOM   3526  N  N   . VAL B 2 160 ? 134.957 116.501 102.067 1.00 28.02  ? 106 VAL E N   1 
ATOM   3527  C  CA  . VAL B 2 160 ? 136.184 116.008 101.458 1.00 27.05  ? 106 VAL E CA  1 
ATOM   3528  C  C   . VAL B 2 160 ? 137.223 117.109 101.574 1.00 30.79  ? 106 VAL E C   1 
ATOM   3529  O  O   . VAL B 2 160 ? 136.933 118.275 101.284 1.00 39.11  ? 106 VAL E O   1 
ATOM   3530  C  CB  . VAL B 2 160 ? 135.965 115.607 99.989  1.00 26.35  ? 106 VAL E CB  1 
ATOM   3531  C  CG1 . VAL B 2 160 ? 137.275 115.257 99.336  1.00 26.22  ? 106 VAL E CG1 1 
ATOM   3532  C  CG2 . VAL B 2 160 ? 135.019 114.440 99.892  1.00 25.40  ? 106 VAL E CG2 1 
ATOM   3533  N  N   . HIS B 2 161 ? 138.420 116.755 102.022 1.00 24.26  ? 107 HIS E N   1 
ATOM   3534  C  CA  . HIS B 2 161 ? 139.465 117.747 102.209 1.00 23.73  ? 107 HIS E CA  1 
ATOM   3535  C  C   . HIS B 2 161 ? 139.886 118.346 100.874 1.00 28.05  ? 107 HIS E C   1 
ATOM   3536  O  O   . HIS B 2 161 ? 140.007 117.641 99.872  1.00 32.12  ? 107 HIS E O   1 
ATOM   3537  C  CB  . HIS B 2 161 ? 140.658 117.113 102.908 1.00 23.30  ? 107 HIS E CB  1 
ATOM   3538  C  CG  . HIS B 2 161 ? 140.328 116.538 104.247 1.00 26.44  ? 107 HIS E CG  1 
ATOM   3539  N  ND1 . HIS B 2 161 ? 140.489 117.242 105.417 1.00 29.06  ? 107 HIS E ND1 1 
ATOM   3540  C  CD2 . HIS B 2 161 ? 139.845 115.326 104.601 1.00 25.51  ? 107 HIS E CD2 1 
ATOM   3541  C  CE1 . HIS B 2 161 ? 140.117 116.490 106.435 1.00 24.35  ? 107 HIS E CE1 1 
ATOM   3542  N  NE2 . HIS B 2 161 ? 139.727 115.321 105.967 1.00 24.32  ? 107 HIS E NE2 1 
ATOM   3543  N  N   . GLY B 2 162 ? 140.111 119.654 100.865 1.00 25.95  ? 108 GLY E N   1 
ATOM   3544  C  CA  . GLY B 2 162 ? 140.372 120.350 99.623  1.00 26.28  ? 108 GLY E CA  1 
ATOM   3545  C  C   . GLY B 2 162 ? 141.584 121.257 99.626  1.00 27.28  ? 108 GLY E C   1 
ATOM   3546  O  O   . GLY B 2 162 ? 141.568 122.309 98.987  1.00 31.56  ? 108 GLY E O   1 
ATOM   3547  N  N   . VAL B 2 163 ? 142.634 120.868 100.343 1.00 24.76  ? 109 VAL E N   1 
ATOM   3548  C  CA  . VAL B 2 163 ? 143.912 121.570 100.337 1.00 24.11  ? 109 VAL E CA  1 
ATOM   3549  C  C   . VAL B 2 163 ? 145.010 120.545 100.088 1.00 25.83  ? 109 VAL E C   1 
ATOM   3550  O  O   . VAL B 2 163 ? 145.071 119.524 100.780 1.00 26.77  ? 109 VAL E O   1 
ATOM   3551  C  CB  . VAL B 2 163 ? 144.146 122.330 101.656 1.00 20.44  ? 109 VAL E CB  1 
ATOM   3552  C  CG1 . VAL B 2 163 ? 145.579 122.755 101.776 1.00 21.63  ? 109 VAL E CG1 1 
ATOM   3553  C  CG2 . VAL B 2 163 ? 143.259 123.538 101.712 1.00 23.53  ? 109 VAL E CG2 1 
ATOM   3554  N  N   . THR B 2 164 ? 145.874 120.804 99.105  1.00 24.53  ? 110 THR E N   1 
ATOM   3555  C  CA  . THR B 2 164 ? 145.873 122.026 98.306  1.00 23.37  ? 110 THR E CA  1 
ATOM   3556  C  C   . THR B 2 164 ? 144.865 121.990 97.167  1.00 26.30  ? 110 THR E C   1 
ATOM   3557  O  O   . THR B 2 164 ? 144.416 123.029 96.700  1.00 30.33  ? 110 THR E O   1 
ATOM   3558  C  CB  . THR B 2 164 ? 147.263 122.303 97.720  1.00 27.50  ? 110 THR E CB  1 
ATOM   3559  O  OG1 . THR B 2 164 ? 147.584 121.301 96.753  1.00 33.19  ? 110 THR E OG1 1 
ATOM   3560  C  CG2 . THR B 2 164 ? 148.313 122.292 98.813  1.00 26.79  ? 110 THR E CG2 1 
ATOM   3561  N  N   . VAL B 2 165 ? 144.522 120.789 96.715  1.00 26.73  ? 111 VAL E N   1 
ATOM   3562  C  CA  . VAL B 2 165 ? 143.390 120.589 95.819  1.00 25.92  ? 111 VAL E CA  1 
ATOM   3563  C  C   . VAL B 2 165 ? 142.470 119.569 96.470  1.00 30.14  ? 111 VAL E C   1 
ATOM   3564  O  O   . VAL B 2 165 ? 142.756 119.075 97.565  1.00 34.29  ? 111 VAL E O   1 
ATOM   3565  C  CB  . VAL B 2 165 ? 143.830 120.130 94.419  1.00 23.77  ? 111 VAL E CB  1 
ATOM   3566  C  CG1 . VAL B 2 165 ? 144.828 121.097 93.833  1.00 25.11  ? 111 VAL E CG1 1 
ATOM   3567  C  CG2 . VAL B 2 165 ? 144.415 118.741 94.479  1.00 24.29  ? 111 VAL E CG2 1 
ATOM   3568  N  N   . LYS B 2 166 ? 141.365 119.245 95.810  1.00 30.29  ? 112 LYS E N   1 
ATOM   3569  C  CA  . LYS B 2 166 ? 140.449 118.245 96.339  1.00 29.55  ? 112 LYS E CA  1 
ATOM   3570  C  C   . LYS B 2 166 ? 141.165 116.910 96.497  1.00 31.81  ? 112 LYS E C   1 
ATOM   3571  O  O   . LYS B 2 166 ? 141.824 116.432 95.572  1.00 35.18  ? 112 LYS E O   1 
ATOM   3572  C  CB  . LYS B 2 166 ? 139.251 118.107 95.406  1.00 33.19  ? 112 LYS E CB  1 
ATOM   3573  C  CG  . LYS B 2 166 ? 138.026 117.496 96.030  1.00 42.18  ? 112 LYS E CG  1 
ATOM   3574  C  CD  . LYS B 2 166 ? 136.902 117.422 95.019  1.00 47.37  ? 112 LYS E CD  1 
ATOM   3575  C  CE  . LYS B 2 166 ? 135.741 116.614 95.547  1.00 49.16  ? 112 LYS E CE  1 
ATOM   3576  N  NZ  . LYS B 2 166 ? 135.190 117.222 96.788  1.00 55.06  ? 112 LYS E NZ  1 
ATOM   3577  N  N   . ASN B 2 167 ? 141.040 116.310 97.681  1.00 27.91  ? 113 ASN E N   1 
ATOM   3578  C  CA  . ASN B 2 167 ? 141.740 115.068 98.008  1.00 24.57  ? 113 ASN E CA  1 
ATOM   3579  C  C   . ASN B 2 167 ? 141.000 113.904 97.362  1.00 29.63  ? 113 ASN E C   1 
ATOM   3580  O  O   . ASN B 2 167 ? 140.248 113.166 97.998  1.00 30.62  ? 113 ASN E O   1 
ATOM   3581  C  CB  . ASN B 2 167 ? 141.846 114.894 99.515  1.00 22.93  ? 113 ASN E CB  1 
ATOM   3582  C  CG  . ASN B 2 167 ? 142.855 115.827 100.139 1.00 25.30  ? 113 ASN E CG  1 
ATOM   3583  O  OD1 . ASN B 2 167 ? 143.802 115.390 100.777 1.00 30.37  ? 113 ASN E OD1 1 
ATOM   3584  N  ND2 . ASN B 2 167 ? 142.667 117.115 99.946  1.00 23.69  ? 113 ASN E ND2 1 
ATOM   3585  N  N   . ARG B 2 168 ? 141.232 113.735 96.065  1.00 32.42  ? 114 ARG E N   1 
ATOM   3586  C  CA  . ARG B 2 168 ? 140.521 112.753 95.263  1.00 29.60  ? 114 ARG E CA  1 
ATOM   3587  C  C   . ARG B 2 168 ? 141.502 112.090 94.308  1.00 31.29  ? 114 ARG E C   1 
ATOM   3588  O  O   . ARG B 2 168 ? 142.403 112.747 93.787  1.00 41.09  ? 114 ARG E O   1 
ATOM   3589  C  CB  . ARG B 2 168 ? 139.374 113.420 94.500  1.00 32.78  ? 114 ARG E CB  1 
ATOM   3590  C  CG  . ARG B 2 168 ? 138.555 112.505 93.634  1.00 35.95  ? 114 ARG E CG  1 
ATOM   3591  C  CD  . ARG B 2 168 ? 137.340 113.229 93.102  1.00 42.08  ? 114 ARG E CD  1 
ATOM   3592  N  NE  . ARG B 2 168 ? 137.682 114.553 92.604  1.00 49.77  ? 114 ARG E NE  1 
ATOM   3593  C  CZ  . ARG B 2 168 ? 136.820 115.386 92.041  1.00 52.09  ? 114 ARG E CZ  1 
ATOM   3594  N  NH1 . ARG B 2 168 ? 135.547 115.068 91.895  1.00 52.96  ? 114 ARG E NH1 1 
ATOM   3595  N  NH2 . ARG B 2 168 ? 137.248 116.570 91.617  1.00 50.75  ? 114 ARG E NH2 1 
ATOM   3596  N  N   . MET B 2 169 ? 141.338 110.786 94.099  1.00 27.33  ? 115 MET E N   1 
ATOM   3597  C  CA  . MET B 2 169 ? 142.237 109.999 93.263  1.00 28.43  ? 115 MET E CA  1 
ATOM   3598  C  C   . MET B 2 169 ? 141.439 109.184 92.263  1.00 32.07  ? 115 MET E C   1 
ATOM   3599  O  O   . MET B 2 169 ? 140.512 108.471 92.651  1.00 36.96  ? 115 MET E O   1 
ATOM   3600  C  CB  . MET B 2 169 ? 143.098 109.051 94.100  1.00 26.11  ? 115 MET E CB  1 
ATOM   3601  C  CG  . MET B 2 169 ? 143.741 107.946 93.277  1.00 30.50  ? 115 MET E CG  1 
ATOM   3602  S  SD  . MET B 2 169 ? 144.763 106.810 94.220  1.00 58.29  ? 115 MET E SD  1 
ATOM   3603  C  CE  . MET B 2 169 ? 143.535 106.036 95.255  1.00 43.71  ? 115 MET E CE  1 
ATOM   3604  N  N   . ILE B 2 170 ? 141.823 109.269 90.992  1.00 32.89  ? 116 ILE E N   1 
ATOM   3605  C  CA  . ILE B 2 170 ? 141.272 108.446 89.921  1.00 32.28  ? 116 ILE E CA  1 
ATOM   3606  C  C   . ILE B 2 170 ? 142.420 107.690 89.272  1.00 34.96  ? 116 ILE E C   1 
ATOM   3607  O  O   . ILE B 2 170 ? 143.357 108.306 88.747  1.00 45.91  ? 116 ILE E O   1 
ATOM   3608  C  CB  . ILE B 2 170 ? 140.526 109.284 88.874  1.00 31.75  ? 116 ILE E CB  1 
ATOM   3609  C  CG1 . ILE B 2 170 ? 139.183 109.754 89.414  1.00 39.23  ? 116 ILE E CG1 1 
ATOM   3610  C  CG2 . ILE B 2 170 ? 140.312 108.480 87.616  1.00 32.30  ? 116 ILE E CG2 1 
ATOM   3611  C  CD1 . ILE B 2 170 ? 138.091 108.731 89.288  1.00 36.81  ? 116 ILE E CD1 1 
ATOM   3612  N  N   . ARG B 2 171 ? 142.340 106.363 89.287  1.00 32.43  ? 117 ARG E N   1 
ATOM   3613  C  CA  . ARG B 2 171 ? 143.341 105.526 88.645  1.00 33.77  ? 117 ARG E CA  1 
ATOM   3614  C  C   . ARG B 2 171 ? 142.648 104.493 87.770  1.00 36.63  ? 117 ARG E C   1 
ATOM   3615  O  O   . ARG B 2 171 ? 141.763 103.770 88.236  1.00 39.10  ? 117 ARG E O   1 
ATOM   3616  C  CB  . ARG B 2 171 ? 144.233 104.846 89.687  1.00 33.67  ? 117 ARG E CB  1 
ATOM   3617  C  CG  . ARG B 2 171 ? 145.443 104.144 89.123  1.00 37.43  ? 117 ARG E CG  1 
ATOM   3618  C  CD  . ARG B 2 171 ? 146.311 103.584 90.228  1.00 44.12  ? 117 ARG E CD  1 
ATOM   3619  N  NE  . ARG B 2 171 ? 146.792 104.638 91.112  1.00 48.71  ? 117 ARG E NE  1 
ATOM   3620  C  CZ  . ARG B 2 171 ? 147.414 104.429 92.262  1.00 40.92  ? 117 ARG E CZ  1 
ATOM   3621  N  NH1 . ARG B 2 171 ? 147.648 103.209 92.711  1.00 35.49  ? 117 ARG E NH1 1 
ATOM   3622  N  NH2 . ARG B 2 171 ? 147.799 105.472 92.987  1.00 35.14  ? 117 ARG E NH2 1 
ATOM   3623  N  N   . LEU B 2 172 ? 143.047 104.433 86.505  1.00 37.25  ? 118 LEU E N   1 
ATOM   3624  C  CA  . LEU B 2 172 ? 142.535 103.465 85.550  1.00 35.87  ? 118 LEU E CA  1 
ATOM   3625  C  C   . LEU B 2 172 ? 143.548 102.351 85.339  1.00 42.71  ? 118 LEU E C   1 
ATOM   3626  O  O   . LEU B 2 172 ? 144.754 102.544 85.496  1.00 51.91  ? 118 LEU E O   1 
ATOM   3627  C  CB  . LEU B 2 172 ? 142.229 104.122 84.204  1.00 38.87  ? 118 LEU E CB  1 
ATOM   3628  C  CG  . LEU B 2 172 ? 141.354 105.369 84.140  1.00 40.34  ? 118 LEU E CG  1 
ATOM   3629  C  CD1 . LEU B 2 172 ? 141.264 105.835 82.712  1.00 33.99  ? 118 LEU E CD1 1 
ATOM   3630  C  CD2 . LEU B 2 172 ? 139.978 105.095 84.680  1.00 41.19  ? 118 LEU E CD2 1 
ATOM   3631  N  N   . HIS B 2 173 ? 143.042 101.188 84.964  1.00 41.85  ? 119 HIS E N   1 
ATOM   3632  C  CA  . HIS B 2 173 ? 143.831 100.001 84.685  1.00 46.18  ? 119 HIS E CA  1 
ATOM   3633  C  C   . HIS B 2 173 ? 143.464 99.502  83.298  1.00 49.28  ? 119 HIS E C   1 
ATOM   3634  O  O   . HIS B 2 173 ? 142.385 99.816  82.788  1.00 50.18  ? 119 HIS E O   1 
ATOM   3635  C  CB  . HIS B 2 173 ? 143.572 98.920  85.743  1.00 44.73  ? 119 HIS E CB  1 
ATOM   3636  C  CG  . HIS B 2 173 ? 143.832 99.379  87.143  1.00 49.27  ? 119 HIS E CG  1 
ATOM   3637  N  ND1 . HIS B 2 173 ? 143.018 100.279 87.795  1.00 46.91  ? 119 HIS E ND1 1 
ATOM   3638  C  CD2 . HIS B 2 173 ? 144.827 99.078  88.008  1.00 55.81  ? 119 HIS E CD2 1 
ATOM   3639  C  CE1 . HIS B 2 173 ? 143.493 100.502 89.006  1.00 44.22  ? 119 HIS E CE1 1 
ATOM   3640  N  NE2 . HIS B 2 173 ? 144.592 99.789  89.160  1.00 56.97  ? 119 HIS E NE2 1 
ATOM   3641  N  N   . PRO B 2 174 ? 144.354 98.748  82.645  1.00 50.92  ? 120 PRO E N   1 
ATOM   3642  C  CA  . PRO B 2 174 ? 144.127 98.416  81.227  1.00 51.59  ? 120 PRO E CA  1 
ATOM   3643  C  C   . PRO B 2 174 ? 142.832 97.677  80.950  1.00 53.24  ? 120 PRO E C   1 
ATOM   3644  O  O   . PRO B 2 174 ? 142.225 97.899  79.897  1.00 55.70  ? 120 PRO E O   1 
ATOM   3645  C  CB  . PRO B 2 174 ? 145.343 97.554  80.875  1.00 53.11  ? 120 PRO E CB  1 
ATOM   3646  C  CG  . PRO B 2 174 ? 146.377 97.957  81.838  1.00 55.11  ? 120 PRO E CG  1 
ATOM   3647  C  CD  . PRO B 2 174 ? 145.663 98.264  83.111  1.00 51.99  ? 120 PRO E CD  1 
ATOM   3648  N  N   . ASP B 2 175 ? 142.380 96.813  81.853  1.00 53.93  ? 121 ASP E N   1 
ATOM   3649  C  CA  . ASP B 2 175 ? 141.168 96.043  81.608  1.00 55.66  ? 121 ASP E CA  1 
ATOM   3650  C  C   . ASP B 2 175 ? 139.897 96.816  81.927  1.00 53.74  ? 121 ASP E C   1 
ATOM   3651  O  O   . ASP B 2 175 ? 138.809 96.242  81.840  1.00 54.92  ? 121 ASP E O   1 
ATOM   3652  C  CB  . ASP B 2 175 ? 141.190 94.742  82.409  1.00 54.73  ? 121 ASP E CB  1 
ATOM   3653  C  CG  . ASP B 2 175 ? 140.995 94.963  83.893  1.00 56.51  ? 121 ASP E CG  1 
ATOM   3654  O  OD1 . ASP B 2 175 ? 141.479 95.982  84.421  1.00 57.72  ? 121 ASP E OD1 1 
ATOM   3655  O  OD2 . ASP B 2 175 ? 140.357 94.107  84.536  1.00 55.59  ? 121 ASP E OD2 1 
ATOM   3656  N  N   . GLY B 2 176 ? 140.004 98.089  82.287  1.00 49.49  ? 122 GLY E N   1 
ATOM   3657  C  CA  . GLY B 2 176 ? 138.850 98.908  82.579  1.00 44.31  ? 122 GLY E CA  1 
ATOM   3658  C  C   . GLY B 2 176 ? 138.556 99.107  84.047  1.00 42.64  ? 122 GLY E C   1 
ATOM   3659  O  O   . GLY B 2 176 ? 137.630 99.851  84.377  1.00 43.54  ? 122 GLY E O   1 
ATOM   3660  N  N   . THR B 2 177 ? 139.313 98.469  84.931  1.00 39.29  ? 123 THR E N   1 
ATOM   3661  C  CA  . THR B 2 177 ? 139.111 98.637  86.360  1.00 35.18  ? 123 THR E CA  1 
ATOM   3662  C  C   . THR B 2 177 ? 139.423 100.065 86.787  1.00 34.19  ? 123 THR E C   1 
ATOM   3663  O  O   . THR B 2 177 ? 140.421 100.652 86.368  1.00 41.71  ? 123 THR E O   1 
ATOM   3664  C  CB  . THR B 2 177 ? 140.002 97.664  87.121  1.00 38.83  ? 123 THR E CB  1 
ATOM   3665  O  OG1 . THR B 2 177 ? 139.607 96.321  86.824  1.00 45.51  ? 123 THR E OG1 1 
ATOM   3666  C  CG2 . THR B 2 177 ? 139.897 97.905  88.606  1.00 33.78  ? 123 THR E CG2 1 
ATOM   3667  N  N   . VAL B 2 178 ? 138.565 100.617 87.636  1.00 28.53  ? 124 VAL E N   1 
ATOM   3668  C  CA  . VAL B 2 178 ? 138.694 101.975 88.140  1.00 27.33  ? 124 VAL E CA  1 
ATOM   3669  C  C   . VAL B 2 178 ? 138.843 101.921 89.651  1.00 31.69  ? 124 VAL E C   1 
ATOM   3670  O  O   . VAL B 2 178 ? 138.055 101.255 90.339  1.00 33.96  ? 124 VAL E O   1 
ATOM   3671  C  CB  . VAL B 2 178 ? 137.486 102.842 87.745  1.00 26.16  ? 124 VAL E CB  1 
ATOM   3672  C  CG1 . VAL B 2 178 ? 137.633 104.241 88.283  1.00 25.55  ? 124 VAL E CG1 1 
ATOM   3673  C  CG2 . VAL B 2 178 ? 137.334 102.873 86.252  1.00 29.22  ? 124 VAL E CG2 1 
ATOM   3674  N  N   . LEU B 2 179 ? 139.856 102.621 90.154  1.00 32.79  ? 125 LEU E N   1 
ATOM   3675  C  CA  . LEU B 2 179 ? 140.052 102.860 91.574  1.00 29.91  ? 125 LEU E CA  1 
ATOM   3676  C  C   . LEU B 2 179 ? 139.805 104.334 91.851  1.00 28.11  ? 125 LEU E C   1 
ATOM   3677  O  O   . LEU B 2 179 ? 140.419 105.204 91.220  1.00 30.88  ? 125 LEU E O   1 
ATOM   3678  C  CB  . LEU B 2 179 ? 141.462 102.455 92.002  1.00 34.48  ? 125 LEU E CB  1 
ATOM   3679  C  CG  . LEU B 2 179 ? 142.081 103.120 93.229  1.00 35.17  ? 125 LEU E CG  1 
ATOM   3680  C  CD1 . LEU B 2 179 ? 141.292 102.850 94.484  1.00 32.62  ? 125 LEU E CD1 1 
ATOM   3681  C  CD2 . LEU B 2 179 ? 143.502 102.645 93.398  1.00 36.44  ? 125 LEU E CD2 1 
ATOM   3682  N  N   . TYR B 2 180 ? 138.904 104.608 92.789  1.00 24.71  ? 126 TYR E N   1 
ATOM   3683  C  CA  . TYR B 2 180 ? 138.440 105.959 93.082  1.00 23.91  ? 126 TYR E CA  1 
ATOM   3684  C  C   . TYR B 2 180 ? 138.560 106.171 94.582  1.00 28.72  ? 126 TYR E C   1 
ATOM   3685  O  O   . TYR B 2 180 ? 137.886 105.496 95.362  1.00 33.13  ? 126 TYR E O   1 
ATOM   3686  C  CB  . TYR B 2 180 ? 137.005 106.137 92.588  1.00 24.97  ? 126 TYR E CB  1 
ATOM   3687  C  CG  . TYR B 2 180 ? 136.293 107.404 92.989  1.00 25.67  ? 126 TYR E CG  1 
ATOM   3688  C  CD1 . TYR B 2 180 ? 136.784 108.648 92.646  1.00 24.25  ? 126 TYR E CD1 1 
ATOM   3689  C  CD2 . TYR B 2 180 ? 135.091 107.346 93.662  1.00 27.49  ? 126 TYR E CD2 1 
ATOM   3690  C  CE1 . TYR B 2 180 ? 136.115 109.794 92.994  1.00 25.70  ? 126 TYR E CE1 1 
ATOM   3691  C  CE2 . TYR B 2 180 ? 134.418 108.481 94.014  1.00 27.87  ? 126 TYR E CE2 1 
ATOM   3692  C  CZ  . TYR B 2 180 ? 134.928 109.702 93.677  1.00 26.31  ? 126 TYR E CZ  1 
ATOM   3693  O  OH  . TYR B 2 180 ? 134.239 110.832 94.038  1.00 30.47  ? 126 TYR E OH  1 
ATOM   3694  N  N   . GLY B 2 181 ? 139.424 107.084 94.986  1.00 26.27  ? 127 GLY E N   1 
ATOM   3695  C  CA  . GLY B 2 181 ? 139.717 107.304 96.393  1.00 23.79  ? 127 GLY E CA  1 
ATOM   3696  C  C   . GLY B 2 181 ? 139.365 108.711 96.829  1.00 25.72  ? 127 GLY E C   1 
ATOM   3697  O  O   . GLY B 2 181 ? 139.551 109.663 96.076  1.00 33.51  ? 127 GLY E O   1 
ATOM   3698  N  N   . LEU B 2 182 ? 138.871 108.832 98.057  1.00 24.58  ? 128 LEU E N   1 
ATOM   3699  C  CA  . LEU B 2 182 ? 138.551 110.115 98.663  1.00 21.24  ? 128 LEU E CA  1 
ATOM   3700  C  C   . LEU B 2 182 ? 139.119 110.147 100.072 1.00 24.30  ? 128 LEU E C   1 
ATOM   3701  O  O   . LEU B 2 182 ? 139.366 109.108 100.679 1.00 35.57  ? 128 LEU E O   1 
ATOM   3702  C  CB  . LEU B 2 182 ? 137.042 110.353 98.716  1.00 21.99  ? 128 LEU E CB  1 
ATOM   3703  C  CG  . LEU B 2 182 ? 136.252 110.399 97.413  1.00 21.31  ? 128 LEU E CG  1 
ATOM   3704  C  CD1 . LEU B 2 182 ? 134.785 110.278 97.708  1.00 19.37  ? 128 LEU E CD1 1 
ATOM   3705  C  CD2 . LEU B 2 182 ? 136.516 111.688 96.691  1.00 24.08  ? 128 LEU E CD2 1 
ATOM   3706  N  N   . ARG B 2 183 ? 139.339 111.347 100.594 1.00 19.94  ? 129 ARG E N   1 
ATOM   3707  C  CA  . ARG B 2 183 ? 139.746 111.521 101.984 1.00 19.86  ? 129 ARG E CA  1 
ATOM   3708  C  C   . ARG B 2 183 ? 138.645 112.294 102.688 1.00 23.30  ? 129 ARG E C   1 
ATOM   3709  O  O   . ARG B 2 183 ? 138.469 113.489 102.443 1.00 29.63  ? 129 ARG E O   1 
ATOM   3710  C  CB  . ARG B 2 183 ? 141.084 112.241 102.099 1.00 21.25  ? 129 ARG E CB  1 
ATOM   3711  C  CG  . ARG B 2 183 ? 141.615 112.251 103.515 1.00 23.51  ? 129 ARG E CG  1 
ATOM   3712  C  CD  . ARG B 2 183 ? 143.099 112.477 103.566 1.00 23.55  ? 129 ARG E CD  1 
ATOM   3713  N  NE  . ARG B 2 183 ? 143.442 113.882 103.415 1.00 25.91  ? 129 ARG E NE  1 
ATOM   3714  C  CZ  . ARG B 2 183 ? 143.766 114.681 104.417 1.00 25.46  ? 129 ARG E CZ  1 
ATOM   3715  N  NH1 . ARG B 2 183 ? 143.833 114.237 105.658 1.00 24.76  ? 129 ARG E NH1 1 
ATOM   3716  N  NH2 . ARG B 2 183 ? 144.023 115.959 104.168 1.00 25.91  ? 129 ARG E NH2 1 
ATOM   3717  N  N   . ILE B 2 184 ? 137.914 111.619 103.569 1.00 19.69  ? 130 ILE E N   1 
ATOM   3718  C  CA  . ILE B 2 184 ? 136.653 112.124 104.094 1.00 19.25  ? 130 ILE E CA  1 
ATOM   3719  C  C   . ILE B 2 184 ? 136.760 112.273 105.602 1.00 24.12  ? 130 ILE E C   1 
ATOM   3720  O  O   . ILE B 2 184 ? 137.219 111.356 106.290 1.00 34.16  ? 130 ILE E O   1 
ATOM   3721  C  CB  . ILE B 2 184 ? 135.486 111.195 103.716 1.00 20.91  ? 130 ILE E CB  1 
ATOM   3722  C  CG1 . ILE B 2 184 ? 135.258 111.226 102.209 1.00 20.82  ? 130 ILE E CG1 1 
ATOM   3723  C  CG2 . ILE B 2 184 ? 134.228 111.593 104.445 1.00 26.90  ? 130 ILE E CG2 1 
ATOM   3724  C  CD1 . ILE B 2 184 ? 134.496 110.057 101.689 1.00 19.72  ? 130 ILE E CD1 1 
ATOM   3725  N  N   . THR B 2 185 ? 136.355 113.433 106.109 1.00 21.08  ? 131 THR E N   1 
ATOM   3726  C  CA  . THR B 2 185 ? 136.132 113.650 107.533 1.00 24.37  ? 131 THR E CA  1 
ATOM   3727  C  C   . THR B 2 185 ? 134.633 113.755 107.760 1.00 28.58  ? 131 THR E C   1 
ATOM   3728  O  O   . THR B 2 185 ? 133.987 114.659 107.227 1.00 34.80  ? 131 THR E O   1 
ATOM   3729  C  CB  . THR B 2 185 ? 136.833 114.909 108.028 1.00 25.84  ? 131 THR E CB  1 
ATOM   3730  O  OG1 . THR B 2 185 ? 138.246 114.698 108.031 1.00 34.33  ? 131 THR E OG1 1 
ATOM   3731  C  CG2 . THR B 2 185 ? 136.389 115.240 109.431 1.00 24.05  ? 131 THR E CG2 1 
ATOM   3732  N  N   . THR B 2 186 ? 134.081 112.829 108.530 1.00 29.83  ? 132 THR E N   1 
ATOM   3733  C  CA  . THR B 2 186 ? 132.642 112.756 108.717 1.00 31.25  ? 132 THR E CA  1 
ATOM   3734  C  C   . THR B 2 186 ? 132.300 112.653 110.194 1.00 32.96  ? 132 THR E C   1 
ATOM   3735  O  O   . THR B 2 186 ? 132.955 111.931 110.946 1.00 35.79  ? 132 THR E O   1 
ATOM   3736  C  CB  . THR B 2 186 ? 132.040 111.564 107.946 1.00 34.51  ? 132 THR E CB  1 
ATOM   3737  O  OG1 . THR B 2 186 ? 130.628 111.515 108.160 1.00 40.77  ? 132 THR E OG1 1 
ATOM   3738  C  CG2 . THR B 2 186 ? 132.649 110.257 108.392 1.00 33.60  ? 132 THR E CG2 1 
ATOM   3739  N  N   . THR B 2 187 ? 131.275 113.388 110.604 1.00 32.31  ? 133 THR E N   1 
ATOM   3740  C  CA  . THR B 2 187 ? 130.684 113.240 111.925 1.00 34.04  ? 133 THR E CA  1 
ATOM   3741  C  C   . THR B 2 187 ? 129.461 112.347 111.802 1.00 36.19  ? 133 THR E C   1 
ATOM   3742  O  O   . THR B 2 187 ? 128.579 112.615 110.989 1.00 39.81  ? 133 THR E O   1 
ATOM   3743  C  CB  . THR B 2 187 ? 130.291 114.593 112.516 1.00 35.02  ? 133 THR E CB  1 
ATOM   3744  O  OG1 . THR B 2 187 ? 131.469 115.346 112.816 1.00 39.15  ? 133 THR E OG1 1 
ATOM   3745  C  CG2 . THR B 2 187 ? 129.505 114.400 113.782 1.00 36.39  ? 133 THR E CG2 1 
ATOM   3746  N  N   . ALA B 2 188 ? 129.425 111.281 112.587 1.00 34.69  ? 134 ALA E N   1 
ATOM   3747  C  CA  . ALA B 2 188 ? 128.380 110.275 112.509 1.00 33.83  ? 134 ALA E CA  1 
ATOM   3748  C  C   . ALA B 2 188 ? 127.656 110.167 113.840 1.00 37.15  ? 134 ALA E C   1 
ATOM   3749  O  O   . ALA B 2 188 ? 128.284 110.189 114.901 1.00 43.82  ? 134 ALA E O   1 
ATOM   3750  C  CB  . ALA B 2 188 ? 128.955 108.920 112.114 1.00 29.87  ? 134 ALA E CB  1 
ATOM   3751  N  N   . ALA B 2 189 ? 126.334 110.041 113.772 1.00 33.12  ? 135 ALA E N   1 
ATOM   3752  C  CA  . ALA B 2 189 ? 125.501 109.989 114.963 1.00 35.61  ? 135 ALA E CA  1 
ATOM   3753  C  C   . ALA B 2 189 ? 125.598 108.627 115.634 1.00 42.72  ? 135 ALA E C   1 
ATOM   3754  O  O   . ALA B 2 189 ? 125.413 107.592 114.992 1.00 44.58  ? 135 ALA E O   1 
ATOM   3755  C  CB  . ALA B 2 189 ? 124.050 110.291 114.602 1.00 35.70  ? 135 ALA E CB  1 
ATOM   3756  N  N   . CYS B 2 190 ? 125.869 108.636 116.936 1.00 49.07  ? 136 CYS E N   1 
ATOM   3757  C  CA  . CYS B 2 190 ? 125.966 107.428 117.743 1.00 52.07  ? 136 CYS E CA  1 
ATOM   3758  C  C   . CYS B 2 190 ? 125.190 107.670 119.025 1.00 58.60  ? 136 CYS E C   1 
ATOM   3759  O  O   . CYS B 2 190 ? 125.532 108.573 119.793 1.00 65.87  ? 136 CYS E O   1 
ATOM   3760  C  CB  . CYS B 2 190 ? 127.430 107.082 118.046 1.00 57.44  ? 136 CYS E CB  1 
ATOM   3761  S  SG  . CYS B 2 190 ? 127.703 105.551 118.973 1.00 83.01  ? 136 CYS E SG  1 
ATOM   3762  N  N   . MET B 2 191 ? 124.138 106.888 119.246 1.00 57.56  ? 137 MET E N   1 
ATOM   3763  C  CA  . MET B 2 191 ? 123.338 107.030 120.454 1.00 58.44  ? 137 MET E CA  1 
ATOM   3764  C  C   . MET B 2 191 ? 123.982 106.262 121.598 1.00 58.66  ? 137 MET E C   1 
ATOM   3765  O  O   . MET B 2 191 ? 124.250 105.064 121.482 1.00 64.12  ? 137 MET E O   1 
ATOM   3766  C  CB  . MET B 2 191 ? 121.914 106.538 120.220 1.00 57.25  ? 137 MET E CB  1 
ATOM   3767  C  CG  . MET B 2 191 ? 121.157 107.337 119.183 1.00 66.47  ? 137 MET E CG  1 
ATOM   3768  S  SD  . MET B 2 191 ? 121.125 109.101 119.554 1.00 79.74  ? 137 MET E SD  1 
ATOM   3769  C  CE  . MET B 2 191 ? 120.233 109.106 121.103 1.00 48.05  ? 137 MET E CE  1 
ATOM   3770  N  N   . MET B 2 192 ? 124.205 106.950 122.711 1.00 53.38  ? 138 MET E N   1 
ATOM   3771  C  CA  . MET B 2 192 ? 124.926 106.401 123.846 1.00 53.75  ? 138 MET E CA  1 
ATOM   3772  C  C   . MET B 2 192 ? 123.994 106.247 125.038 1.00 62.25  ? 138 MET E C   1 
ATOM   3773  O  O   . MET B 2 192 ? 123.149 107.108 125.294 1.00 64.60  ? 138 MET E O   1 
ATOM   3774  C  CB  . MET B 2 192 ? 126.102 107.297 124.225 1.00 51.77  ? 138 MET E CB  1 
ATOM   3775  C  CG  . MET B 2 192 ? 127.077 107.537 123.100 1.00 57.85  ? 138 MET E CG  1 
ATOM   3776  S  SD  . MET B 2 192 ? 128.387 108.676 123.557 1.00 77.17  ? 138 MET E SD  1 
ATOM   3777  C  CE  . MET B 2 192 ? 129.001 109.100 121.937 1.00 64.42  ? 138 MET E CE  1 
ATOM   3778  N  N   . ASP B 2 193 ? 124.147 105.141 125.755 1.00 65.05  ? 139 ASP E N   1 
ATOM   3779  C  CA  . ASP B 2 193 ? 123.420 104.890 126.995 1.00 67.63  ? 139 ASP E CA  1 
ATOM   3780  C  C   . ASP B 2 193 ? 124.374 105.192 128.144 1.00 68.94  ? 139 ASP E C   1 
ATOM   3781  O  O   . ASP B 2 193 ? 125.232 104.377 128.482 1.00 72.61  ? 139 ASP E O   1 
ATOM   3782  C  CB  . ASP B 2 193 ? 122.915 103.453 127.039 1.00 70.53  ? 139 ASP E CB  1 
ATOM   3783  C  CG  . ASP B 2 193 ? 121.930 103.214 128.162 1.00 84.45  ? 139 ASP E CG  1 
ATOM   3784  O  OD1 . ASP B 2 193 ? 121.699 104.141 128.964 1.00 84.98  ? 139 ASP E OD1 1 
ATOM   3785  O  OD2 . ASP B 2 193 ? 121.381 102.095 128.240 1.00 89.12  ? 139 ASP E OD2 1 
ATOM   3786  N  N   . LEU B 2 194 ? 124.218 106.367 128.750 1.00 65.45  ? 140 LEU E N   1 
ATOM   3787  C  CA  . LEU B 2 194 ? 125.156 106.859 129.750 1.00 65.48  ? 140 LEU E CA  1 
ATOM   3788  C  C   . LEU B 2 194 ? 124.698 106.572 131.175 1.00 71.42  ? 140 LEU E C   1 
ATOM   3789  O  O   . LEU B 2 194 ? 125.046 107.313 132.098 1.00 73.13  ? 140 LEU E O   1 
ATOM   3790  C  CB  . LEU B 2 194 ? 125.385 108.356 129.558 1.00 62.09  ? 140 LEU E CB  1 
ATOM   3791  C  CG  . LEU B 2 194 ? 125.871 108.787 128.178 1.00 59.95  ? 140 LEU E CG  1 
ATOM   3792  C  CD1 . LEU B 2 194 ? 126.226 110.247 128.189 1.00 61.96  ? 140 LEU E CD1 1 
ATOM   3793  C  CD2 . LEU B 2 194 ? 127.057 107.956 127.748 1.00 64.00  ? 140 LEU E CD2 1 
ATOM   3794  N  N   . ARG B 2 195 ? 123.925 105.506 131.377 1.00 71.11  ? 141 ARG E N   1 
ATOM   3795  C  CA  . ARG B 2 195 ? 123.471 105.179 132.724 1.00 72.95  ? 141 ARG E CA  1 
ATOM   3796  C  C   . ARG B 2 195 ? 124.615 104.673 133.593 1.00 74.67  ? 141 ARG E C   1 
ATOM   3797  O  O   . ARG B 2 195 ? 124.714 105.042 134.768 1.00 79.31  ? 141 ARG E O   1 
ATOM   3798  C  CB  . ARG B 2 195 ? 122.346 104.153 132.661 1.00 76.82  ? 141 ARG E CB  1 
ATOM   3799  C  CG  . ARG B 2 195 ? 120.987 104.779 132.460 1.00 84.23  ? 141 ARG E CG  1 
ATOM   3800  C  CD  . ARG B 2 195 ? 119.969 103.771 131.978 1.00 86.59  ? 141 ARG E CD  1 
ATOM   3801  N  NE  . ARG B 2 195 ? 118.654 104.383 131.836 1.00 94.38  ? 141 ARG E NE  1 
ATOM   3802  C  CZ  . ARG B 2 195 ? 118.260 105.079 130.779 1.00 93.81  ? 141 ARG E CZ  1 
ATOM   3803  N  NH1 . ARG B 2 195 ? 119.057 105.269 129.741 1.00 89.31  ? 141 ARG E NH1 1 
ATOM   3804  N  NH2 . ARG B 2 195 ? 117.035 105.594 130.762 1.00 92.16  ? 141 ARG E NH2 1 
ATOM   3805  N  N   . ARG B 2 196 ? 125.491 103.840 133.039 1.00 66.77  ? 142 ARG E N   1 
ATOM   3806  C  CA  . ARG B 2 196 ? 126.653 103.360 133.773 1.00 61.54  ? 142 ARG E CA  1 
ATOM   3807  C  C   . ARG B 2 196 ? 127.831 104.314 133.697 1.00 63.20  ? 142 ARG E C   1 
ATOM   3808  O  O   . ARG B 2 196 ? 128.936 103.933 134.086 1.00 64.05  ? 142 ARG E O   1 
ATOM   3809  C  CB  . ARG B 2 196 ? 127.084 101.991 133.252 1.00 58.26  ? 142 ARG E CB  1 
ATOM   3810  C  CG  . ARG B 2 196 ? 126.245 100.835 133.728 1.00 64.12  ? 142 ARG E CG  1 
ATOM   3811  C  CD  . ARG B 2 196 ? 126.717 99.546  133.085 1.00 73.52  ? 142 ARG E CD  1 
ATOM   3812  N  NE  . ARG B 2 196 ? 126.031 98.379  133.620 1.00 97.69  ? 142 ARG E NE  1 
ATOM   3813  C  CZ  . ARG B 2 196 ? 126.478 97.645  134.627 1.00 100.59 ? 142 ARG E CZ  1 
ATOM   3814  N  NH1 . ARG B 2 196 ? 127.618 97.928  135.235 1.00 95.02  ? 142 ARG E NH1 1 
ATOM   3815  N  NH2 . ARG B 2 196 ? 125.766 96.598  135.034 1.00 101.31 ? 142 ARG E NH2 1 
ATOM   3816  N  N   . TYR B 2 197 ? 127.623 105.525 133.198 1.00 64.43  ? 143 TYR E N   1 
ATOM   3817  C  CA  . TYR B 2 197 ? 128.708 106.482 133.069 1.00 59.96  ? 143 TYR E CA  1 
ATOM   3818  C  C   . TYR B 2 197 ? 129.316 106.761 134.439 1.00 67.08  ? 143 TYR E C   1 
ATOM   3819  O  O   . TYR B 2 197 ? 128.587 106.880 135.429 1.00 78.73  ? 143 TYR E O   1 
ATOM   3820  C  CB  . TYR B 2 197 ? 128.185 107.778 132.451 1.00 59.01  ? 143 TYR E CB  1 
ATOM   3821  C  CG  . TYR B 2 197 ? 129.228 108.819 132.141 1.00 57.64  ? 143 TYR E CG  1 
ATOM   3822  C  CD1 . TYR B 2 197 ? 129.695 109.676 133.121 1.00 62.65  ? 143 TYR E CD1 1 
ATOM   3823  C  CD2 . TYR B 2 197 ? 129.722 108.967 130.858 1.00 58.81  ? 143 TYR E CD2 1 
ATOM   3824  C  CE1 . TYR B 2 197 ? 130.635 110.633 132.835 1.00 65.28  ? 143 TYR E CE1 1 
ATOM   3825  C  CE2 . TYR B 2 197 ? 130.661 109.922 130.563 1.00 58.92  ? 143 TYR E CE2 1 
ATOM   3826  C  CZ  . TYR B 2 197 ? 131.115 110.752 131.555 1.00 60.43  ? 143 TYR E CZ  1 
ATOM   3827  O  OH  . TYR B 2 197 ? 132.056 111.707 131.264 1.00 61.78  ? 143 TYR E OH  1 
ATOM   3828  N  N   . PRO B 2 198 ? 130.641 106.870 134.539 1.00 64.69  ? 144 PRO E N   1 
ATOM   3829  C  CA  . PRO B 2 198 ? 131.624 106.743 133.461 1.00 66.02  ? 144 PRO E CA  1 
ATOM   3830  C  C   . PRO B 2 198 ? 132.185 105.334 133.284 1.00 66.86  ? 144 PRO E C   1 
ATOM   3831  O  O   . PRO B 2 198 ? 133.320 105.180 132.856 1.00 72.18  ? 144 PRO E O   1 
ATOM   3832  C  CB  . PRO B 2 198 ? 132.706 107.730 133.896 1.00 59.14  ? 144 PRO E CB  1 
ATOM   3833  C  CG  . PRO B 2 198 ? 132.693 107.628 135.377 1.00 59.81  ? 144 PRO E CG  1 
ATOM   3834  C  CD  . PRO B 2 198 ? 131.248 107.444 135.751 1.00 63.09  ? 144 PRO E CD  1 
ATOM   3835  N  N   . LEU B 2 199 ? 131.428 104.285 133.579 1.00 62.64  ? 145 LEU E N   1 
ATOM   3836  C  CA  . LEU B 2 199 ? 131.893 102.914 133.422 1.00 60.94  ? 145 LEU E CA  1 
ATOM   3837  C  C   . LEU B 2 199 ? 131.092 102.179 132.356 1.00 65.33  ? 145 LEU E C   1 
ATOM   3838  O  O   . LEU B 2 199 ? 130.747 101.007 132.510 1.00 61.17  ? 145 LEU E O   1 
ATOM   3839  C  CB  . LEU B 2 199 ? 131.827 102.163 134.747 1.00 63.89  ? 145 LEU E CB  1 
ATOM   3840  C  CG  . LEU B 2 199 ? 132.741 102.647 135.875 1.00 69.32  ? 145 LEU E CG  1 
ATOM   3841  C  CD1 . LEU B 2 199 ? 132.101 103.767 136.683 1.00 64.32  ? 145 LEU E CD1 1 
ATOM   3842  C  CD2 . LEU B 2 199 ? 133.117 101.484 136.771 1.00 74.66  ? 145 LEU E CD2 1 
ATOM   3843  N  N   . ASP B 2 200 ? 130.800 102.857 131.251 1.00 69.18  ? 146 ASP E N   1 
ATOM   3844  C  CA  . ASP B 2 200 ? 129.921 102.339 130.215 1.00 62.09  ? 146 ASP E CA  1 
ATOM   3845  C  C   . ASP B 2 200 ? 130.713 101.789 129.036 1.00 64.51  ? 146 ASP E C   1 
ATOM   3846  O  O   . ASP B 2 200 ? 131.906 102.054 128.874 1.00 66.01  ? 146 ASP E O   1 
ATOM   3847  C  CB  . ASP B 2 200 ? 128.967 103.430 129.732 1.00 60.75  ? 146 ASP E CB  1 
ATOM   3848  C  CG  . ASP B 2 200 ? 129.691 104.687 129.322 1.00 63.18  ? 146 ASP E CG  1 
ATOM   3849  O  OD1 . ASP B 2 200 ? 130.773 104.951 129.881 1.00 61.30  ? 146 ASP E OD1 1 
ATOM   3850  O  OD2 . ASP B 2 200 ? 129.184 105.413 128.445 1.00 64.36  ? 146 ASP E OD2 1 
ATOM   3851  N  N   . GLU B 2 201 ? 130.022 101.004 128.212 1.00 66.10  ? 147 GLU E N   1 
ATOM   3852  C  CA  . GLU B 2 201 ? 130.576 100.433 126.991 1.00 64.77  ? 147 GLU E CA  1 
ATOM   3853  C  C   . GLU B 2 201 ? 129.639 100.769 125.842 1.00 65.18  ? 147 GLU E C   1 
ATOM   3854  O  O   . GLU B 2 201 ? 128.453 100.430 125.891 1.00 70.41  ? 147 GLU E O   1 
ATOM   3855  C  CB  . GLU B 2 201 ? 130.743 98.919  127.129 1.00 66.48  ? 147 GLU E CB  1 
ATOM   3856  C  CG  . GLU B 2 201 ? 131.336 98.230  125.922 1.00 67.56  ? 147 GLU E CG  1 
ATOM   3857  C  CD  . GLU B 2 201 ? 131.172 96.727  125.989 1.00 80.90  ? 147 GLU E CD  1 
ATOM   3858  O  OE1 . GLU B 2 201 ? 130.149 96.267  126.535 1.00 82.44  ? 147 GLU E OE1 1 
ATOM   3859  O  OE2 . GLU B 2 201 ? 132.066 96.003  125.504 1.00 86.35  ? 147 GLU E OE2 1 
ATOM   3860  N  N   . GLN B 2 202 ? 130.163 101.420 124.810 1.00 58.80  ? 148 GLN E N   1 
ATOM   3861  C  CA  . GLN B 2 202 ? 129.354 101.894 123.696 1.00 56.37  ? 148 GLN E CA  1 
ATOM   3862  C  C   . GLN B 2 202 ? 129.678 101.118 122.426 1.00 50.92  ? 148 GLN E C   1 
ATOM   3863  O  O   . GLN B 2 202 ? 130.670 100.398 122.343 1.00 53.45  ? 148 GLN E O   1 
ATOM   3864  C  CB  . GLN B 2 202 ? 129.571 103.393 123.476 1.00 52.34  ? 148 GLN E CB  1 
ATOM   3865  C  CG  . GLN B 2 202 ? 129.326 104.231 124.714 1.00 53.24  ? 148 GLN E CG  1 
ATOM   3866  C  CD  . GLN B 2 202 ? 127.909 104.103 125.231 1.00 61.30  ? 148 GLN E CD  1 
ATOM   3867  O  OE1 . GLN B 2 202 ? 126.970 103.946 124.457 1.00 67.21  ? 148 GLN E OE1 1 
ATOM   3868  N  NE2 . GLN B 2 202 ? 127.749 104.161 126.543 1.00 59.52  ? 148 GLN E NE2 1 
ATOM   3869  N  N   . ASN B 2 203 ? 128.817 101.281 121.425 1.00 48.19  ? 149 ASN E N   1 
ATOM   3870  C  CA  . ASN B 2 203 ? 128.980 100.637 120.124 1.00 46.10  ? 149 ASN E CA  1 
ATOM   3871  C  C   . ASN B 2 203 ? 128.581 101.651 119.063 1.00 48.38  ? 149 ASN E C   1 
ATOM   3872  O  O   . ASN B 2 203 ? 127.405 102.009 118.961 1.00 56.45  ? 149 ASN E O   1 
ATOM   3873  C  CB  . ASN B 2 203 ? 128.134 99.365  120.028 1.00 44.84  ? 149 ASN E CB  1 
ATOM   3874  C  CG  . ASN B 2 203 ? 128.122 98.767  118.635 1.00 44.89  ? 149 ASN E CG  1 
ATOM   3875  O  OD1 . ASN B 2 203 ? 128.953 99.093  117.797 1.00 49.00  ? 149 ASN E OD1 1 
ATOM   3876  N  ND2 . ASN B 2 203 ? 127.172 97.877  118.389 1.00 49.03  ? 149 ASN E ND2 1 
ATOM   3877  N  N   . CYS B 2 204 ? 129.549 102.118 118.282 1.00 42.58  ? 150 CYS E N   1 
ATOM   3878  C  CA  . CYS B 2 204 ? 129.316 103.164 117.295 1.00 45.50  ? 150 CYS E CA  1 
ATOM   3879  C  C   . CYS B 2 204 ? 129.592 102.625 115.901 1.00 44.21  ? 150 CYS E C   1 
ATOM   3880  O  O   . CYS B 2 204 ? 130.608 101.964 115.679 1.00 48.41  ? 150 CYS E O   1 
ATOM   3881  C  CB  . CYS B 2 204 ? 130.183 104.394 117.573 1.00 48.43  ? 150 CYS E CB  1 
ATOM   3882  S  SG  . CYS B 2 204 ? 129.726 105.328 119.063 1.00 88.11  ? 150 CYS E SG  1 
ATOM   3883  N  N   . THR B 2 205 ? 128.697 102.913 114.965 1.00 42.47  ? 151 THR E N   1 
ATOM   3884  C  CA  . THR B 2 205 ? 128.750 102.324 113.637 1.00 42.67  ? 151 THR E CA  1 
ATOM   3885  C  C   . THR B 2 205 ? 128.903 103.396 112.568 1.00 39.29  ? 151 THR E C   1 
ATOM   3886  O  O   . THR B 2 205 ? 128.828 104.596 112.830 1.00 40.79  ? 151 THR E O   1 
ATOM   3887  C  CB  . THR B 2 205 ? 127.496 101.491 113.342 1.00 46.90  ? 151 THR E CB  1 
ATOM   3888  O  OG1 . THR B 2 205 ? 126.381 102.360 113.129 1.00 45.40  ? 151 THR E OG1 1 
ATOM   3889  C  CG2 . THR B 2 205 ? 127.185 100.569 114.497 1.00 50.29  ? 151 THR E CG2 1 
ATOM   3890  N  N   . LEU B 2 206 ? 129.152 102.922 111.353 1.00 35.35  ? 152 LEU E N   1 
ATOM   3891  C  CA  . LEU B 2 206 ? 129.106 103.730 110.145 1.00 33.41  ? 152 LEU E CA  1 
ATOM   3892  C  C   . LEU B 2 206 ? 128.432 102.894 109.073 1.00 34.68  ? 152 LEU E C   1 
ATOM   3893  O  O   . LEU B 2 206 ? 128.876 101.774 108.795 1.00 39.96  ? 152 LEU E O   1 
ATOM   3894  C  CB  . LEU B 2 206 ? 130.505 104.155 109.698 1.00 33.33  ? 152 LEU E CB  1 
ATOM   3895  C  CG  . LEU B 2 206 ? 130.566 105.092 108.493 1.00 34.04  ? 152 LEU E CG  1 
ATOM   3896  C  CD1 . LEU B 2 206 ? 130.136 106.492 108.872 1.00 30.90  ? 152 LEU E CD1 1 
ATOM   3897  C  CD2 . LEU B 2 206 ? 131.951 105.103 107.892 1.00 28.28  ? 152 LEU E CD2 1 
ATOM   3898  N  N   . GLU B 2 207 ? 127.362 103.428 108.490 1.00 33.99  ? 153 GLU E N   1 
ATOM   3899  C  CA  . GLU B 2 207 ? 126.581 102.739 107.472 1.00 35.18  ? 153 GLU E CA  1 
ATOM   3900  C  C   . GLU B 2 207 ? 126.936 103.295 106.103 1.00 37.56  ? 153 GLU E C   1 
ATOM   3901  O  O   . GLU B 2 207 ? 126.966 104.511 105.913 1.00 42.38  ? 153 GLU E O   1 
ATOM   3902  C  CB  . GLU B 2 207 ? 125.083 102.907 107.717 1.00 35.15  ? 153 GLU E CB  1 
ATOM   3903  C  CG  . GLU B 2 207 ? 124.658 102.767 109.156 1.00 42.38  ? 153 GLU E CG  1 
ATOM   3904  C  CD  . GLU B 2 207 ? 124.856 101.370 109.694 1.00 54.29  ? 153 GLU E CD  1 
ATOM   3905  O  OE1 . GLU B 2 207 ? 124.614 100.398 108.951 1.00 51.32  ? 153 GLU E OE1 1 
ATOM   3906  O  OE2 . GLU B 2 207 ? 125.254 101.241 110.867 1.00 59.01  ? 153 GLU E OE2 1 
ATOM   3907  N  N   . ILE B 2 208 ? 127.198 102.405 105.156 1.00 34.54  ? 154 ILE E N   1 
ATOM   3908  C  CA  . ILE B 2 208 ? 127.565 102.764 103.795 1.00 35.73  ? 154 ILE E CA  1 
ATOM   3909  C  C   . ILE B 2 208 ? 126.520 102.151 102.883 1.00 39.22  ? 154 ILE E C   1 
ATOM   3910  O  O   . ILE B 2 208 ? 126.312 100.933 102.911 1.00 44.35  ? 154 ILE E O   1 
ATOM   3911  C  CB  . ILE B 2 208 ? 128.966 102.253 103.438 1.00 33.04  ? 154 ILE E CB  1 
ATOM   3912  C  CG1 . ILE B 2 208 ? 130.008 102.831 104.391 1.00 30.94  ? 154 ILE E CG1 1 
ATOM   3913  C  CG2 . ILE B 2 208 ? 129.302 102.576 102.007 1.00 35.51  ? 154 ILE E CG2 1 
ATOM   3914  C  CD1 . ILE B 2 208 ? 131.293 102.059 104.395 1.00 32.53  ? 154 ILE E CD1 1 
ATOM   3915  N  N   . GLU B 2 209 ? 125.869 102.979 102.072 1.00 35.01  ? 155 GLU E N   1 
ATOM   3916  C  CA  . GLU B 2 209 ? 124.782 102.486 101.245 1.00 36.93  ? 155 GLU E CA  1 
ATOM   3917  C  C   . GLU B 2 209 ? 124.788 103.189 99.897  1.00 39.07  ? 155 GLU E C   1 
ATOM   3918  O  O   . GLU B 2 209 ? 125.383 104.252 99.729  1.00 43.50  ? 155 GLU E O   1 
ATOM   3919  C  CB  . GLU B 2 209 ? 123.427 102.672 101.936 1.00 36.90  ? 155 GLU E CB  1 
ATOM   3920  C  CG  . GLU B 2 209 ? 122.380 101.679 101.472 1.00 41.37  ? 155 GLU E CG  1 
ATOM   3921  C  CD  . GLU B 2 209 ? 121.068 101.818 102.197 1.00 54.97  ? 155 GLU E CD  1 
ATOM   3922  O  OE1 . GLU B 2 209 ? 120.910 102.777 102.977 1.00 57.00  ? 155 GLU E OE1 1 
ATOM   3923  O  OE2 . GLU B 2 209 ? 120.188 100.961 101.985 1.00 59.12  ? 155 GLU E OE2 1 
ATOM   3924  N  N   . SER B 2 210 ? 124.125 102.570 98.929  1.00 36.52  ? 156 SER E N   1 
ATOM   3925  C  CA  . SER B 2 210 ? 123.914 103.163 97.619  1.00 31.94  ? 156 SER E CA  1 
ATOM   3926  C  C   . SER B 2 210 ? 122.550 103.828 97.601  1.00 36.50  ? 156 SER E C   1 
ATOM   3927  O  O   . SER B 2 210 ? 121.550 103.200 97.952  1.00 45.30  ? 156 SER E O   1 
ATOM   3928  C  CB  . SER B 2 210 ? 123.994 102.111 96.517  1.00 32.89  ? 156 SER E CB  1 
ATOM   3929  O  OG  . SER B 2 210 ? 123.749 102.695 95.254  1.00 36.77  ? 156 SER E OG  1 
ATOM   3930  N  N   . TYR B 2 211 ? 122.504 105.091 97.186  1.00 34.43  ? 157 TYR E N   1 
ATOM   3931  C  CA  . TYR B 2 211 ? 121.256 105.831 97.305  1.00 31.97  ? 157 TYR E CA  1 
ATOM   3932  C  C   . TYR B 2 211 ? 120.277 105.486 96.191  1.00 31.71  ? 157 TYR E C   1 
ATOM   3933  O  O   . TYR B 2 211 ? 119.093 105.262 96.449  1.00 33.99  ? 157 TYR E O   1 
ATOM   3934  C  CB  . TYR B 2 211 ? 121.518 107.335 97.320  1.00 27.22  ? 157 TYR E CB  1 
ATOM   3935  C  CG  . TYR B 2 211 ? 120.322 108.100 97.812  1.00 27.51  ? 157 TYR E CG  1 
ATOM   3936  C  CD1 . TYR B 2 211 ? 119.303 108.463 96.950  1.00 28.49  ? 157 TYR E CD1 1 
ATOM   3937  C  CD2 . TYR B 2 211 ? 120.197 108.433 99.146  1.00 30.09  ? 157 TYR E CD2 1 
ATOM   3938  C  CE1 . TYR B 2 211 ? 118.207 109.135 97.401  1.00 30.85  ? 157 TYR E CE1 1 
ATOM   3939  C  CE2 . TYR B 2 211 ? 119.105 109.112 99.602  1.00 30.40  ? 157 TYR E CE2 1 
ATOM   3940  C  CZ  . TYR B 2 211 ? 118.113 109.458 98.728  1.00 32.04  ? 157 TYR E CZ  1 
ATOM   3941  O  OH  . TYR B 2 211 ? 117.022 110.140 99.188  1.00 41.17  ? 157 TYR E OH  1 
ATOM   3942  N  N   . GLY B 2 212 ? 120.739 105.460 94.951  1.00 27.91  ? 158 GLY E N   1 
ATOM   3943  C  CA  . GLY B 2 212 ? 119.819 105.355 93.841  1.00 30.32  ? 158 GLY E CA  1 
ATOM   3944  C  C   . GLY B 2 212 ? 119.701 103.976 93.234  1.00 36.08  ? 158 GLY E C   1 
ATOM   3945  O  O   . GLY B 2 212 ? 118.627 103.591 92.768  1.00 40.07  ? 158 GLY E O   1 
ATOM   3946  N  N   . TYR B 2 213 ? 120.793 103.224 93.233  1.00 34.81  ? 159 TYR E N   1 
ATOM   3947  C  CA  . TYR B 2 213 ? 120.838 101.932 92.568  1.00 39.86  ? 159 TYR E CA  1 
ATOM   3948  C  C   . TYR B 2 213 ? 120.489 100.834 93.562  1.00 42.68  ? 159 TYR E C   1 
ATOM   3949  O  O   . TYR B 2 213 ? 121.121 100.720 94.615  1.00 42.79  ? 159 TYR E O   1 
ATOM   3950  C  CB  . TYR B 2 213 ? 122.216 101.697 91.957  1.00 39.65  ? 159 TYR E CB  1 
ATOM   3951  C  CG  . TYR B 2 213 ? 122.621 102.756 90.965  1.00 40.60  ? 159 TYR E CG  1 
ATOM   3952  C  CD1 . TYR B 2 213 ? 122.109 102.758 89.677  1.00 36.86  ? 159 TYR E CD1 1 
ATOM   3953  C  CD2 . TYR B 2 213 ? 123.513 103.755 91.315  1.00 36.99  ? 159 TYR E CD2 1 
ATOM   3954  C  CE1 . TYR B 2 213 ? 122.473 103.720 88.771  1.00 33.66  ? 159 TYR E CE1 1 
ATOM   3955  C  CE2 . TYR B 2 213 ? 123.884 104.720 90.415  1.00 35.33  ? 159 TYR E CE2 1 
ATOM   3956  C  CZ  . TYR B 2 213 ? 123.360 104.700 89.145  1.00 36.07  ? 159 TYR E CZ  1 
ATOM   3957  O  OH  . TYR B 2 213 ? 123.729 105.661 88.240  1.00 37.80  ? 159 TYR E OH  1 
ATOM   3958  N  N   . THR B 2 214 ? 119.487 100.031 93.225  1.00 44.46  ? 160 THR E N   1 
ATOM   3959  C  CA  . THR B 2 214 ? 119.067 98.929  94.075  1.00 42.07  ? 160 THR E CA  1 
ATOM   3960  C  C   . THR B 2 214 ? 119.995 97.741  93.847  1.00 46.73  ? 160 THR E C   1 
ATOM   3961  O  O   . THR B 2 214 ? 120.990 97.830  93.125  1.00 53.15  ? 160 THR E O   1 
ATOM   3962  C  CB  . THR B 2 214 ? 117.614 98.571  93.797  1.00 41.05  ? 160 THR E CB  1 
ATOM   3963  O  OG1 . THR B 2 214 ? 117.500 98.054  92.469  1.00 45.81  ? 160 THR E OG1 1 
ATOM   3964  C  CG2 . THR B 2 214 ? 116.736 99.792  93.929  1.00 38.86  ? 160 THR E CG2 1 
ATOM   3965  N  N   . THR B 2 215 ? 119.669 96.601  94.452  1.00 45.29  ? 161 THR E N   1 
ATOM   3966  C  CA  . THR B 2 215 ? 120.466 95.398  94.265  1.00 45.01  ? 161 THR E CA  1 
ATOM   3967  C  C   . THR B 2 215 ? 120.392 94.859  92.844  1.00 51.12  ? 161 THR E C   1 
ATOM   3968  O  O   . THR B 2 215 ? 121.195 93.991  92.489  1.00 54.31  ? 161 THR E O   1 
ATOM   3969  C  CB  . THR B 2 215 ? 120.027 94.318  95.250  1.00 48.89  ? 161 THR E CB  1 
ATOM   3970  O  OG1 . THR B 2 215 ? 118.613 94.123  95.144  1.00 56.17  ? 161 THR E OG1 1 
ATOM   3971  C  CG2 . THR B 2 215 ? 120.367 94.727  96.665  1.00 41.95  ? 161 THR E CG2 1 
ATOM   3972  N  N   . ASP B 2 216 ? 119.454 95.337  92.029  1.00 51.04  ? 162 ASP E N   1 
ATOM   3973  C  CA  . ASP B 2 216 ? 119.434 94.970  90.622  1.00 53.73  ? 162 ASP E CA  1 
ATOM   3974  C  C   . ASP B 2 216 ? 120.474 95.719  89.807  1.00 53.23  ? 162 ASP E C   1 
ATOM   3975  O  O   . ASP B 2 216 ? 120.779 95.301  88.688  1.00 60.83  ? 162 ASP E O   1 
ATOM   3976  C  CB  . ASP B 2 216 ? 118.054 95.233  90.021  1.00 60.99  ? 162 ASP E CB  1 
ATOM   3977  C  CG  . ASP B 2 216 ? 116.965 94.421  90.681  1.00 73.84  ? 162 ASP E CG  1 
ATOM   3978  O  OD1 . ASP B 2 216 ? 117.261 93.316  91.180  1.00 72.95  ? 162 ASP E OD1 1 
ATOM   3979  O  OD2 . ASP B 2 216 ? 115.809 94.887  90.698  1.00 80.53  ? 162 ASP E OD2 1 
ATOM   3980  N  N   . ASP B 2 217 ? 121.017 96.818  90.334  1.00 49.12  ? 163 ASP E N   1 
ATOM   3981  C  CA  . ASP B 2 217 ? 121.956 97.646  89.595  1.00 48.29  ? 163 ASP E CA  1 
ATOM   3982  C  C   . ASP B 2 217 ? 123.360 97.653  90.171  1.00 48.00  ? 163 ASP E C   1 
ATOM   3983  O  O   . ASP B 2 217 ? 124.303 97.956  89.438  1.00 55.27  ? 163 ASP E O   1 
ATOM   3984  C  CB  . ASP B 2 217 ? 121.461 99.096  89.533  1.00 50.28  ? 163 ASP E CB  1 
ATOM   3985  C  CG  . ASP B 2 217 ? 120.134 99.235  88.832  1.00 59.71  ? 163 ASP E CG  1 
ATOM   3986  O  OD1 . ASP B 2 217 ? 119.782 98.350  88.030  1.00 71.16  ? 163 ASP E OD1 1 
ATOM   3987  O  OD2 . ASP B 2 217 ? 119.443 100.242 89.074  1.00 57.03  ? 163 ASP E OD2 1 
ATOM   3988  N  N   . ILE B 2 218 ? 123.528 97.322  91.449  1.00 45.34  ? 164 ILE E N   1 
ATOM   3989  C  CA  . ILE B 2 218 ? 124.812 97.452  92.123  1.00 43.54  ? 164 ILE E CA  1 
ATOM   3990  C  C   . ILE B 2 218 ? 124.860 96.434  93.248  1.00 46.81  ? 164 ILE E C   1 
ATOM   3991  O  O   . ILE B 2 218 ? 123.832 95.934  93.703  1.00 49.27  ? 164 ILE E O   1 
ATOM   3992  C  CB  . ILE B 2 218 ? 125.018 98.887  92.663  1.00 36.96  ? 164 ILE E CB  1 
ATOM   3993  C  CG1 . ILE B 2 218 ? 126.492 99.259  92.690  1.00 35.21  ? 164 ILE E CG1 1 
ATOM   3994  C  CG2 . ILE B 2 218 ? 124.443 99.021  94.045  1.00 41.35  ? 164 ILE E CG2 1 
ATOM   3995  C  CD1 . ILE B 2 218 ? 126.722 100.708 92.995  1.00 35.17  ? 164 ILE E CD1 1 
ATOM   3996  N  N   . GLU B 2 219 ? 126.072 96.106  93.684  1.00 46.35  ? 165 GLU E N   1 
ATOM   3997  C  CA  . GLU B 2 219 ? 126.246 95.268  94.861  1.00 44.68  ? 165 GLU E CA  1 
ATOM   3998  C  C   . GLU B 2 219 ? 127.595 95.571  95.489  1.00 43.97  ? 165 GLU E C   1 
ATOM   3999  O  O   . GLU B 2 219 ? 128.605 95.646  94.787  1.00 43.81  ? 165 GLU E O   1 
ATOM   4000  C  CB  . GLU B 2 219 ? 126.129 93.783  94.514  1.00 44.12  ? 165 GLU E CB  1 
ATOM   4001  C  CG  . GLU B 2 219 ? 126.927 93.346  93.319  1.00 56.17  ? 165 GLU E CG  1 
ATOM   4002  C  CD  . GLU B 2 219 ? 126.802 91.860  93.065  1.00 71.65  ? 165 GLU E CD  1 
ATOM   4003  O  OE1 . GLU B 2 219 ? 126.379 91.133  93.989  1.00 73.24  ? 165 GLU E OE1 1 
ATOM   4004  O  OE2 . GLU B 2 219 ? 127.123 91.417  91.943  1.00 74.97  ? 165 GLU E OE2 1 
ATOM   4005  N  N   . PHE B 2 220 ? 127.602 95.752  96.802  1.00 43.30  ? 166 PHE E N   1 
ATOM   4006  C  CA  . PHE B 2 220 ? 128.809 96.101  97.529  1.00 35.94  ? 166 PHE E CA  1 
ATOM   4007  C  C   . PHE B 2 220 ? 129.474 94.853  98.088  1.00 38.07  ? 166 PHE E C   1 
ATOM   4008  O  O   . PHE B 2 220 ? 128.856 93.798  98.224  1.00 48.55  ? 166 PHE E O   1 
ATOM   4009  C  CB  . PHE B 2 220 ? 128.496 97.060  98.676  1.00 33.13  ? 166 PHE E CB  1 
ATOM   4010  C  CG  . PHE B 2 220 ? 128.034 98.413  98.238  1.00 35.93  ? 166 PHE E CG  1 
ATOM   4011  C  CD1 . PHE B 2 220 ? 128.046 98.775  96.909  1.00 41.31  ? 166 PHE E CD1 1 
ATOM   4012  C  CD2 . PHE B 2 220 ? 127.604 99.334  99.167  1.00 36.75  ? 166 PHE E CD2 1 
ATOM   4013  C  CE1 . PHE B 2 220 ? 127.630 100.020 96.518  1.00 38.61  ? 166 PHE E CE1 1 
ATOM   4014  C  CE2 . PHE B 2 220 ? 127.188 100.579 98.779  1.00 37.93  ? 166 PHE E CE2 1 
ATOM   4015  C  CZ  . PHE B 2 220 ? 127.199 100.923 97.452  1.00 37.35  ? 166 PHE E CZ  1 
ATOM   4016  N  N   . TYR B 2 221 ? 130.756 94.987  98.408  1.00 33.83  ? 167 TYR E N   1 
ATOM   4017  C  CA  . TYR B 2 221 ? 131.454 93.992  99.206  1.00 36.32  ? 167 TYR E CA  1 
ATOM   4018  C  C   . TYR B 2 221 ? 132.696 94.641  99.789  1.00 38.76  ? 167 TYR E C   1 
ATOM   4019  O  O   . TYR B 2 221 ? 133.171 95.663  99.292  1.00 38.96  ? 167 TYR E O   1 
ATOM   4020  C  CB  . TYR B 2 221 ? 131.812 92.743  98.392  1.00 32.19  ? 167 TYR E CB  1 
ATOM   4021  C  CG  . TYR B 2 221 ? 132.822 92.951  97.291  1.00 36.54  ? 167 TYR E CG  1 
ATOM   4022  C  CD1 . TYR B 2 221 ? 134.180 92.813  97.530  1.00 37.71  ? 167 TYR E CD1 1 
ATOM   4023  C  CD2 . TYR B 2 221 ? 132.416 93.251  96.004  1.00 37.59  ? 167 TYR E CD2 1 
ATOM   4024  C  CE1 . TYR B 2 221 ? 135.102 92.995  96.525  1.00 39.92  ? 167 TYR E CE1 1 
ATOM   4025  C  CE2 . TYR B 2 221 ? 133.327 93.432  94.997  1.00 39.55  ? 167 TYR E CE2 1 
ATOM   4026  C  CZ  . TYR B 2 221 ? 134.668 93.301  95.260  1.00 46.32  ? 167 TYR E CZ  1 
ATOM   4027  O  OH  . TYR B 2 221 ? 135.579 93.484  94.250  1.00 52.56  ? 167 TYR E OH  1 
ATOM   4028  N  N   . TRP B 2 222 ? 133.208 94.046  100.859 1.00 37.63  ? 168 TRP E N   1 
ATOM   4029  C  CA  . TRP B 2 222 ? 134.477 94.476  101.425 1.00 34.42  ? 168 TRP E CA  1 
ATOM   4030  C  C   . TRP B 2 222 ? 135.616 93.852  100.637 1.00 39.42  ? 168 TRP E C   1 
ATOM   4031  O  O   . TRP B 2 222 ? 135.659 92.634  100.455 1.00 49.22  ? 168 TRP E O   1 
ATOM   4032  C  CB  . TRP B 2 222 ? 134.580 94.084  102.894 1.00 33.13  ? 168 TRP E CB  1 
ATOM   4033  C  CG  . TRP B 2 222 ? 133.652 94.820  103.785 1.00 31.81  ? 168 TRP E CG  1 
ATOM   4034  C  CD1 . TRP B 2 222 ? 132.541 94.330  104.387 1.00 33.00  ? 168 TRP E CD1 1 
ATOM   4035  C  CD2 . TRP B 2 222 ? 133.754 96.189  104.179 1.00 34.72  ? 168 TRP E CD2 1 
ATOM   4036  N  NE1 . TRP B 2 222 ? 131.941 95.305  105.139 1.00 33.13  ? 168 TRP E NE1 1 
ATOM   4037  C  CE2 . TRP B 2 222 ? 132.670 96.457  105.028 1.00 33.71  ? 168 TRP E CE2 1 
ATOM   4038  C  CE3 . TRP B 2 222 ? 134.660 97.212  103.902 1.00 33.20  ? 168 TRP E CE3 1 
ATOM   4039  C  CZ2 . TRP B 2 222 ? 132.463 97.705  105.593 1.00 30.48  ? 168 TRP E CZ2 1 
ATOM   4040  C  CZ3 . TRP B 2 222 ? 134.452 98.445  104.465 1.00 29.84  ? 168 TRP E CZ3 1 
ATOM   4041  C  CH2 . TRP B 2 222 ? 133.364 98.683  105.303 1.00 27.12  ? 168 TRP E CH2 1 
ATOM   4042  N  N   . ARG B 2 223 ? 136.533 94.686  100.166 1.00 37.34  ? 169 ARG E N   1 
ATOM   4043  C  CA  . ARG B 2 223 ? 137.626 94.233  99.312  1.00 37.77  ? 169 ARG E CA  1 
ATOM   4044  C  C   . ARG B 2 223 ? 138.771 93.775  100.202 1.00 44.46  ? 169 ARG E C   1 
ATOM   4045  O  O   . ARG B 2 223 ? 139.576 94.583  100.666 1.00 48.98  ? 169 ARG E O   1 
ATOM   4046  C  CB  . ARG B 2 223 ? 138.055 95.338  98.360  1.00 34.22  ? 169 ARG E CB  1 
ATOM   4047  C  CG  . ARG B 2 223 ? 139.058 94.884  97.333  1.00 35.13  ? 169 ARG E CG  1 
ATOM   4048  C  CD  . ARG B 2 223 ? 139.174 95.882  96.221  1.00 41.40  ? 169 ARG E CD  1 
ATOM   4049  N  NE  . ARG B 2 223 ? 140.140 95.472  95.212  1.00 48.14  ? 169 ARG E NE  1 
ATOM   4050  C  CZ  . ARG B 2 223 ? 141.416 95.825  95.214  1.00 50.17  ? 169 ARG E CZ  1 
ATOM   4051  N  NH1 . ARG B 2 223 ? 141.922 96.587  96.168  1.00 46.89  ? 169 ARG E NH1 1 
ATOM   4052  N  NH2 . ARG B 2 223 ? 142.205 95.403  94.232  1.00 49.83  ? 169 ARG E NH2 1 
ATOM   4053  N  N   . GLY B 2 224 ? 138.851 92.470  100.433 1.00 46.42  ? 170 GLY E N   1 
ATOM   4054  C  CA  . GLY B 2 224 ? 139.852 91.893  101.308 1.00 50.97  ? 170 GLY E CA  1 
ATOM   4055  C  C   . GLY B 2 224 ? 139.292 91.096  102.462 1.00 57.56  ? 170 GLY E C   1 
ATOM   4056  O  O   . GLY B 2 224 ? 140.076 90.595  103.279 1.00 62.84  ? 170 GLY E O   1 
ATOM   4057  N  N   . GLY B 2 225 ? 137.979 90.936  102.570 1.00 54.35  ? 171 GLY E N   1 
ATOM   4058  C  CA  . GLY B 2 225 ? 137.427 90.219  103.705 1.00 58.62  ? 171 GLY E CA  1 
ATOM   4059  C  C   . GLY B 2 225 ? 137.555 91.039  104.971 1.00 61.04  ? 171 GLY E C   1 
ATOM   4060  O  O   . GLY B 2 225 ? 137.197 92.219  105.008 1.00 61.08  ? 171 GLY E O   1 
ATOM   4061  N  N   . ASP B 2 226 ? 138.063 90.411  106.030 1.00 65.59  ? 172 ASP E N   1 
ATOM   4062  C  CA  . ASP B 2 226 ? 138.223 91.082  107.313 1.00 65.77  ? 172 ASP E CA  1 
ATOM   4063  C  C   . ASP B 2 226 ? 139.384 92.063  107.332 1.00 64.32  ? 172 ASP E C   1 
ATOM   4064  O  O   . ASP B 2 226 ? 139.515 92.822  108.297 1.00 63.32  ? 172 ASP E O   1 
ATOM   4065  C  CB  . ASP B 2 226 ? 138.416 90.052  108.424 1.00 75.43  ? 172 ASP E CB  1 
ATOM   4066  C  CG  . ASP B 2 226 ? 137.256 89.091  108.529 1.00 90.28  ? 172 ASP E CG  1 
ATOM   4067  O  OD1 . ASP B 2 226 ? 136.110 89.507  108.255 1.00 87.09  ? 172 ASP E OD1 1 
ATOM   4068  O  OD2 . ASP B 2 226 ? 137.489 87.917  108.883 1.00 99.69  ? 172 ASP E OD2 1 
ATOM   4069  N  N   . LYS B 2 227 ? 140.223 92.066  106.302 1.00 58.24  ? 173 LYS E N   1 
ATOM   4070  C  CA  . LYS B 2 227 ? 141.347 92.982  106.207 1.00 56.40  ? 173 LYS E CA  1 
ATOM   4071  C  C   . LYS B 2 227 ? 141.012 94.222  105.393 1.00 54.65  ? 173 LYS E C   1 
ATOM   4072  O  O   . LYS B 2 227 ? 141.916 94.982  105.037 1.00 54.28  ? 173 LYS E O   1 
ATOM   4073  C  CB  . LYS B 2 227 ? 142.554 92.264  105.602 1.00 59.66  ? 173 LYS E CB  1 
ATOM   4074  C  CG  . LYS B 2 227 ? 142.892 90.958  106.293 1.00 64.69  ? 173 LYS E CG  1 
ATOM   4075  C  CD  . LYS B 2 227 ? 144.093 90.278  105.660 1.00 73.01  ? 173 LYS E CD  1 
ATOM   4076  C  CE  . LYS B 2 227 ? 145.376 91.030  105.956 1.00 73.79  ? 173 LYS E CE  1 
ATOM   4077  N  NZ  . LYS B 2 227 ? 146.574 90.344  105.392 1.00 76.27  ? 173 LYS E NZ  1 
ATOM   4078  N  N   . ALA B 2 228 ? 139.732 94.434  105.084 1.00 51.59  ? 174 ALA E N   1 
ATOM   4079  C  CA  . ALA B 2 228 ? 139.340 95.582  104.274 1.00 43.40  ? 174 ALA E CA  1 
ATOM   4080  C  C   . ALA B 2 228 ? 139.632 96.893  104.988 1.00 44.37  ? 174 ALA E C   1 
ATOM   4081  O  O   . ALA B 2 228 ? 140.093 97.855  104.365 1.00 45.65  ? 174 ALA E O   1 
ATOM   4082  C  CB  . ALA B 2 228 ? 137.861 95.486  103.917 1.00 40.32  ? 174 ALA E CB  1 
ATOM   4083  N  N   . VAL B 2 229 ? 139.374 96.954  106.289 1.00 42.40  ? 175 VAL E N   1 
ATOM   4084  C  CA  . VAL B 2 229 ? 139.565 98.164  107.079 1.00 39.16  ? 175 VAL E CA  1 
ATOM   4085  C  C   . VAL B 2 229 ? 140.915 98.096  107.775 1.00 45.36  ? 175 VAL E C   1 
ATOM   4086  O  O   . VAL B 2 229 ? 141.273 97.067  108.359 1.00 48.74  ? 175 VAL E O   1 
ATOM   4087  C  CB  . VAL B 2 229 ? 138.428 98.353  108.093 1.00 36.83  ? 175 VAL E CB  1 
ATOM   4088  C  CG1 . VAL B 2 229 ? 138.697 99.559  108.966 1.00 36.59  ? 175 VAL E CG1 1 
ATOM   4089  C  CG2 . VAL B 2 229 ? 137.126 98.523  107.367 1.00 32.85  ? 175 VAL E CG2 1 
ATOM   4090  N  N   . THR B 2 230 ? 141.667 99.192  107.706 1.00 43.30  ? 176 THR E N   1 
ATOM   4091  C  CA  . THR B 2 230 ? 143.026 99.261  108.212 1.00 43.15  ? 176 THR E CA  1 
ATOM   4092  C  C   . THR B 2 230 ? 143.155 100.438 109.169 1.00 44.59  ? 176 THR E C   1 
ATOM   4093  O  O   . THR B 2 230 ? 142.454 101.442 109.038 1.00 45.06  ? 176 THR E O   1 
ATOM   4094  C  CB  . THR B 2 230 ? 144.031 99.416  107.064 1.00 43.10  ? 176 THR E CB  1 
ATOM   4095  O  OG1 . THR B 2 230 ? 143.773 98.427  106.064 1.00 43.77  ? 176 THR E OG1 1 
ATOM   4096  C  CG2 . THR B 2 230 ? 145.450 99.248  107.558 1.00 49.45  ? 176 THR E CG2 1 
ATOM   4097  N  N   . GLY B 2 231 ? 144.041 100.299 110.148 1.00 47.95  ? 177 GLY E N   1 
ATOM   4098  C  CA  . GLY B 2 231 ? 144.409 101.406 111.000 1.00 52.49  ? 177 GLY E CA  1 
ATOM   4099  C  C   . GLY B 2 231 ? 143.643 101.525 112.296 1.00 60.67  ? 177 GLY E C   1 
ATOM   4100  O  O   . GLY B 2 231 ? 143.831 102.513 113.011 1.00 64.98  ? 177 GLY E O   1 
ATOM   4101  N  N   . VAL B 2 232 ? 142.776 100.566 112.618 1.00 62.82  ? 178 VAL E N   1 
ATOM   4102  C  CA  . VAL B 2 232 ? 142.021 100.648 113.863 1.00 59.69  ? 178 VAL E CA  1 
ATOM   4103  C  C   . VAL B 2 232 ? 142.933 100.428 115.060 1.00 66.38  ? 178 VAL E C   1 
ATOM   4104  O  O   . VAL B 2 232 ? 142.739 101.027 116.124 1.00 67.90  ? 178 VAL E O   1 
ATOM   4105  C  CB  . VAL B 2 232 ? 140.855 99.647  113.852 1.00 54.75  ? 178 VAL E CB  1 
ATOM   4106  C  CG1 . VAL B 2 232 ? 139.963 99.886  115.045 1.00 50.72  ? 178 VAL E CG1 1 
ATOM   4107  C  CG2 . VAL B 2 232 ? 140.071 99.773  112.571 1.00 51.14  ? 178 VAL E CG2 1 
ATOM   4108  N  N   . GLU B 2 233 ? 143.930 99.556  114.914 1.00 70.92  ? 179 GLU E N   1 
ATOM   4109  C  CA  . GLU B 2 233 ? 144.817 99.233  116.022 1.00 72.02  ? 179 GLU E CA  1 
ATOM   4110  C  C   . GLU B 2 233 ? 145.748 100.382 116.389 1.00 73.25  ? 179 GLU E C   1 
ATOM   4111  O  O   . GLU B 2 233 ? 146.311 100.375 117.486 1.00 77.64  ? 179 GLU E O   1 
ATOM   4112  C  CB  . GLU B 2 233 ? 145.639 97.990  115.687 1.00 69.07  ? 179 GLU E CB  1 
ATOM   4113  C  CG  . GLU B 2 233 ? 144.822 96.714  115.572 1.00 74.63  ? 179 GLU E CG  1 
ATOM   4114  C  CD  . GLU B 2 233 ? 144.221 96.515  114.195 1.00 82.02  ? 179 GLU E CD  1 
ATOM   4115  O  OE1 . GLU B 2 233 ? 144.728 97.115  113.226 1.00 85.03  ? 179 GLU E OE1 1 
ATOM   4116  O  OE2 . GLU B 2 233 ? 143.241 95.750  114.081 1.00 77.76  ? 179 GLU E OE2 1 
ATOM   4117  N  N   . ARG B 2 234 ? 145.927 101.359 115.508 1.00 70.03  ? 180 ARG E N   1 
ATOM   4118  C  CA  . ARG B 2 234 ? 146.821 102.476 115.772 1.00 68.59  ? 180 ARG E CA  1 
ATOM   4119  C  C   . ARG B 2 234 ? 146.125 103.672 116.404 1.00 71.42  ? 180 ARG E C   1 
ATOM   4120  O  O   . ARG B 2 234 ? 146.799 104.649 116.737 1.00 80.45  ? 180 ARG E O   1 
ATOM   4121  C  CB  . ARG B 2 234 ? 147.501 102.926 114.479 1.00 72.89  ? 180 ARG E CB  1 
ATOM   4122  C  CG  . ARG B 2 234 ? 148.364 101.875 113.820 1.00 80.92  ? 180 ARG E CG  1 
ATOM   4123  C  CD  . ARG B 2 234 ? 148.984 102.405 112.534 1.00 88.09  ? 180 ARG E CD  1 
ATOM   4124  N  NE  . ARG B 2 234 ? 147.985 102.680 111.508 1.00 92.69  ? 180 ARG E NE  1 
ATOM   4125  C  CZ  . ARG B 2 234 ? 147.501 103.884 111.232 1.00 87.20  ? 180 ARG E CZ  1 
ATOM   4126  N  NH1 . ARG B 2 234 ? 147.910 104.960 111.882 1.00 81.62  ? 180 ARG E NH1 1 
ATOM   4127  N  NH2 . ARG B 2 234 ? 146.581 104.010 110.280 1.00 74.87  ? 180 ARG E NH2 1 
ATOM   4128  N  N   . ILE B 2 235 ? 144.809 103.633 116.569 1.00 69.25  ? 181 ILE E N   1 
ATOM   4129  C  CA  . ILE B 2 235 ? 144.078 104.781 117.093 1.00 71.94  ? 181 ILE E CA  1 
ATOM   4130  C  C   . ILE B 2 235 ? 144.230 104.825 118.605 1.00 80.64  ? 181 ILE E C   1 
ATOM   4131  O  O   . ILE B 2 235 ? 144.009 103.822 119.293 1.00 84.21  ? 181 ILE E O   1 
ATOM   4132  C  CB  . ILE B 2 235 ? 142.597 104.716 116.699 1.00 69.02  ? 181 ILE E CB  1 
ATOM   4133  C  CG1 . ILE B 2 235 ? 142.447 104.463 115.206 1.00 69.57  ? 181 ILE E CG1 1 
ATOM   4134  C  CG2 . ILE B 2 235 ? 141.907 106.003 117.065 1.00 60.42  ? 181 ILE E CG2 1 
ATOM   4135  C  CD1 . ILE B 2 235 ? 141.036 104.150 114.807 1.00 61.48  ? 181 ILE E CD1 1 
ATOM   4136  N  N   . GLU B 2 236 ? 144.602 105.990 119.127 1.00 82.53  ? 182 GLU E N   1 
ATOM   4137  C  CA  . GLU B 2 236 ? 144.700 106.216 120.563 1.00 79.01  ? 182 GLU E CA  1 
ATOM   4138  C  C   . GLU B 2 236 ? 143.696 107.291 120.952 1.00 73.71  ? 182 GLU E C   1 
ATOM   4139  O  O   . GLU B 2 236 ? 143.753 108.413 120.440 1.00 76.27  ? 182 GLU E O   1 
ATOM   4140  C  CB  . GLU B 2 236 ? 146.117 106.634 120.963 1.00 84.22  ? 182 GLU E CB  1 
ATOM   4141  C  CG  . GLU B 2 236 ? 147.222 105.706 120.470 1.00 90.34  ? 182 GLU E CG  1 
ATOM   4142  C  CD  . GLU B 2 236 ? 147.226 104.351 121.165 1.00 99.18  ? 182 GLU E CD  1 
ATOM   4143  O  OE1 . GLU B 2 236 ? 146.627 104.227 122.255 1.00 97.50  ? 182 GLU E OE1 1 
ATOM   4144  O  OE2 . GLU B 2 236 ? 147.835 103.408 120.618 1.00 96.27  ? 182 GLU E OE2 1 
ATOM   4145  N  N   . LEU B 2 237 ? 142.780 106.946 121.851 1.00 69.23  ? 183 LEU E N   1 
ATOM   4146  C  CA  . LEU B 2 237 ? 141.808 107.882 122.378 1.00 66.50  ? 183 LEU E CA  1 
ATOM   4147  C  C   . LEU B 2 237 ? 142.056 108.090 123.865 1.00 73.35  ? 183 LEU E C   1 
ATOM   4148  O  O   . LEU B 2 237 ? 142.200 107.109 124.606 1.00 77.79  ? 183 LEU E O   1 
ATOM   4149  C  CB  . LEU B 2 237 ? 140.380 107.381 122.151 1.00 62.44  ? 183 LEU E CB  1 
ATOM   4150  C  CG  . LEU B 2 237 ? 139.910 107.414 120.701 1.00 59.56  ? 183 LEU E CG  1 
ATOM   4151  C  CD1 . LEU B 2 237 ? 138.626 106.634 120.534 1.00 54.14  ? 183 LEU E CD1 1 
ATOM   4152  C  CD2 . LEU B 2 237 ? 139.719 108.847 120.280 1.00 54.89  ? 183 LEU E CD2 1 
ATOM   4153  N  N   . PRO B 2 238 ? 142.137 109.336 124.333 1.00 74.16  ? 184 PRO E N   1 
ATOM   4154  C  CA  . PRO B 2 238 ? 142.426 109.560 125.758 1.00 71.51  ? 184 PRO E CA  1 
ATOM   4155  C  C   . PRO B 2 238 ? 141.423 108.922 126.700 1.00 68.51  ? 184 PRO E C   1 
ATOM   4156  O  O   . PRO B 2 238 ? 141.811 108.412 127.757 1.00 73.13  ? 184 PRO E O   1 
ATOM   4157  C  CB  . PRO B 2 238 ? 142.408 111.089 125.870 1.00 75.28  ? 184 PRO E CB  1 
ATOM   4158  C  CG  . PRO B 2 238 ? 142.766 111.560 124.505 1.00 81.00  ? 184 PRO E CG  1 
ATOM   4159  C  CD  . PRO B 2 238 ? 142.139 110.587 123.561 1.00 76.18  ? 184 PRO E CD  1 
ATOM   4160  N  N   . GLN B 2 239 ? 140.142 108.921 126.342 1.00 63.68  ? 185 GLN E N   1 
ATOM   4161  C  CA  . GLN B 2 239 ? 139.098 108.459 127.242 1.00 59.44  ? 185 GLN E CA  1 
ATOM   4162  C  C   . GLN B 2 239 ? 138.572 107.077 126.894 1.00 60.26  ? 185 GLN E C   1 
ATOM   4163  O  O   . GLN B 2 239 ? 137.914 106.453 127.731 1.00 59.33  ? 185 GLN E O   1 
ATOM   4164  C  CB  . GLN B 2 239 ? 137.937 109.462 127.243 1.00 60.01  ? 185 GLN E CB  1 
ATOM   4165  C  CG  . GLN B 2 239 ? 136.939 109.301 128.368 1.00 67.27  ? 185 GLN E CG  1 
ATOM   4166  C  CD  . GLN B 2 239 ? 135.872 110.376 128.344 1.00 72.55  ? 185 GLN E CD  1 
ATOM   4167  O  OE1 . GLN B 2 239 ? 134.796 110.218 128.921 1.00 67.96  ? 185 GLN E OE1 1 
ATOM   4168  N  NE2 . GLN B 2 239 ? 136.167 111.480 127.671 1.00 75.78  ? 185 GLN E NE2 1 
ATOM   4169  N  N   . PHE B 2 240 ? 138.849 106.582 125.693 1.00 64.54  ? 186 PHE E N   1 
ATOM   4170  C  CA  . PHE B 2 240 ? 138.302 105.318 125.229 1.00 60.56  ? 186 PHE E CA  1 
ATOM   4171  C  C   . PHE B 2 240 ? 139.419 104.407 124.757 1.00 62.50  ? 186 PHE E C   1 
ATOM   4172  O  O   . PHE B 2 240 ? 140.484 104.865 124.337 1.00 66.95  ? 186 PHE E O   1 
ATOM   4173  C  CB  . PHE B 2 240 ? 137.309 105.512 124.079 1.00 53.13  ? 186 PHE E CB  1 
ATOM   4174  C  CG  . PHE B 2 240 ? 136.011 106.133 124.491 1.00 52.86  ? 186 PHE E CG  1 
ATOM   4175  C  CD1 . PHE B 2 240 ? 135.851 107.502 124.478 1.00 51.72  ? 186 PHE E CD1 1 
ATOM   4176  C  CD2 . PHE B 2 240 ? 134.948 105.345 124.880 1.00 50.52  ? 186 PHE E CD2 1 
ATOM   4177  C  CE1 . PHE B 2 240 ? 134.662 108.071 124.851 1.00 50.77  ? 186 PHE E CE1 1 
ATOM   4178  C  CE2 . PHE B 2 240 ? 133.757 105.908 125.247 1.00 50.90  ? 186 PHE E CE2 1 
ATOM   4179  C  CZ  . PHE B 2 240 ? 133.613 107.275 125.233 1.00 52.32  ? 186 PHE E CZ  1 
ATOM   4180  N  N   . SER B 2 241 ? 139.163 103.107 124.831 1.00 56.11  ? 187 SER E N   1 
ATOM   4181  C  CA  . SER B 2 241 ? 140.008 102.112 124.192 1.00 57.51  ? 187 SER E CA  1 
ATOM   4182  C  C   . SER B 2 241 ? 139.114 101.211 123.359 1.00 58.75  ? 187 SER E C   1 
ATOM   4183  O  O   . SER B 2 241 ? 138.096 100.719 123.853 1.00 62.74  ? 187 SER E O   1 
ATOM   4184  C  CB  . SER B 2 241 ? 140.799 101.300 125.219 1.00 58.34  ? 187 SER E CB  1 
ATOM   4185  O  OG  . SER B 2 241 ? 139.940 100.695 126.164 1.00 70.77  ? 187 SER E OG  1 
ATOM   4186  N  N   . ILE B 2 242 ? 139.482 101.013 122.098 1.00 54.43  ? 188 ILE E N   1 
ATOM   4187  C  CA  . ILE B 2 242 ? 138.675 100.215 121.184 1.00 51.52  ? 188 ILE E CA  1 
ATOM   4188  C  C   . ILE B 2 242 ? 138.902 98.740  121.473 1.00 52.96  ? 188 ILE E C   1 
ATOM   4189  O  O   . ILE B 2 242 ? 140.043 98.267  121.502 1.00 54.93  ? 188 ILE E O   1 
ATOM   4190  C  CB  . ILE B 2 242 ? 139.007 100.554 119.724 1.00 46.88  ? 188 ILE E CB  1 
ATOM   4191  C  CG1 . ILE B 2 242 ? 138.755 102.034 119.457 1.00 52.09  ? 188 ILE E CG1 1 
ATOM   4192  C  CG2 . ILE B 2 242 ? 138.176 99.715  118.785 1.00 44.98  ? 188 ILE E CG2 1 
ATOM   4193  C  CD1 . ILE B 2 242 ? 138.912 102.427 118.016 1.00 57.29  ? 188 ILE E CD1 1 
ATOM   4194  N  N   . VAL B 2 243 ? 137.816 98.008  121.682 1.00 54.62  ? 189 VAL E N   1 
ATOM   4195  C  CA  . VAL B 2 243 ? 137.910 96.593  122.014 1.00 55.24  ? 189 VAL E CA  1 
ATOM   4196  C  C   . VAL B 2 243 ? 137.815 95.721  120.771 1.00 58.36  ? 189 VAL E C   1 
ATOM   4197  O  O   . VAL B 2 243 ? 138.524 94.721  120.652 1.00 61.74  ? 189 VAL E O   1 
ATOM   4198  C  CB  . VAL B 2 243 ? 136.821 96.231  123.039 1.00 55.58  ? 189 VAL E CB  1 
ATOM   4199  C  CG1 . VAL B 2 243 ? 137.013 94.812  123.532 1.00 58.41  ? 189 VAL E CG1 1 
ATOM   4200  C  CG2 . VAL B 2 243 ? 136.844 97.209  124.190 1.00 51.87  ? 189 VAL E CG2 1 
ATOM   4201  N  N   . GLU B 2 244 ? 136.946 96.083  119.834 1.00 58.51  ? 190 GLU E N   1 
ATOM   4202  C  CA  . GLU B 2 244 ? 136.694 95.254  118.668 1.00 56.95  ? 190 GLU E CA  1 
ATOM   4203  C  C   . GLU B 2 244 ? 136.133 96.126  117.558 1.00 54.91  ? 190 GLU E C   1 
ATOM   4204  O  O   . GLU B 2 244 ? 135.466 97.128  117.820 1.00 56.70  ? 190 GLU E O   1 
ATOM   4205  C  CB  . GLU B 2 244 ? 135.721 94.122  119.010 1.00 54.96  ? 190 GLU E CB  1 
ATOM   4206  C  CG  . GLU B 2 244 ? 135.584 93.066  117.938 1.00 62.15  ? 190 GLU E CG  1 
ATOM   4207  C  CD  . GLU B 2 244 ? 134.579 92.003  118.311 1.00 73.00  ? 190 GLU E CD  1 
ATOM   4208  O  OE1 . GLU B 2 244 ? 134.185 91.949  119.493 1.00 74.43  ? 190 GLU E OE1 1 
ATOM   4209  O  OE2 . GLU B 2 244 ? 134.177 91.225  117.423 1.00 76.08  ? 190 GLU E OE2 1 
ATOM   4210  N  N   . HIS B 2 245 ? 136.416 95.743  116.316 1.00 48.66  ? 191 HIS E N   1 
ATOM   4211  C  CA  . HIS B 2 245 ? 135.770 96.338  115.157 1.00 47.76  ? 191 HIS E CA  1 
ATOM   4212  C  C   . HIS B 2 245 ? 135.256 95.222  114.263 1.00 47.49  ? 191 HIS E C   1 
ATOM   4213  O  O   . HIS B 2 245 ? 135.914 94.192  114.100 1.00 53.13  ? 191 HIS E O   1 
ATOM   4214  C  CB  . HIS B 2 245 ? 136.716 97.272  114.384 1.00 50.62  ? 191 HIS E CB  1 
ATOM   4215  C  CG  . HIS B 2 245 ? 137.639 96.567  113.444 1.00 55.73  ? 191 HIS E CG  1 
ATOM   4216  N  ND1 . HIS B 2 245 ? 138.835 96.017  113.847 1.00 59.97  ? 191 HIS E ND1 1 
ATOM   4217  C  CD2 . HIS B 2 245 ? 137.546 96.330  112.115 1.00 50.11  ? 191 HIS E CD2 1 
ATOM   4218  C  CE1 . HIS B 2 245 ? 139.434 95.463  112.810 1.00 61.43  ? 191 HIS E CE1 1 
ATOM   4219  N  NE2 . HIS B 2 245 ? 138.673 95.639  111.746 1.00 54.48  ? 191 HIS E NE2 1 
ATOM   4220  N  N   . ARG B 2 246 ? 134.072 95.424  113.699 1.00 45.48  ? 192 ARG E N   1 
ATOM   4221  C  CA  . ARG B 2 246 ? 133.371 94.373  112.979 1.00 45.12  ? 192 ARG E CA  1 
ATOM   4222  C  C   . ARG B 2 246 ? 132.806 94.915  111.674 1.00 44.72  ? 192 ARG E C   1 
ATOM   4223  O  O   . ARG B 2 246 ? 132.359 96.065  111.606 1.00 45.44  ? 192 ARG E O   1 
ATOM   4224  C  CB  . ARG B 2 246 ? 132.259 93.783  113.851 1.00 48.78  ? 192 ARG E CB  1 
ATOM   4225  C  CG  . ARG B 2 246 ? 131.567 92.573  113.271 1.00 54.43  ? 192 ARG E CG  1 
ATOM   4226  C  CD  . ARG B 2 246 ? 131.432 91.478  114.310 1.00 64.74  ? 192 ARG E CD  1 
ATOM   4227  N  NE  . ARG B 2 246 ? 130.926 91.976  115.583 1.00 65.14  ? 192 ARG E NE  1 
ATOM   4228  C  CZ  . ARG B 2 246 ? 130.654 91.204  116.626 1.00 67.11  ? 192 ARG E CZ  1 
ATOM   4229  N  NH1 . ARG B 2 246 ? 130.834 89.895  116.580 1.00 70.94  ? 192 ARG E NH1 1 
ATOM   4230  N  NH2 . ARG B 2 246 ? 130.191 91.757  117.740 1.00 61.45  ? 192 ARG E NH2 1 
ATOM   4231  N  N   . LEU B 2 247 ? 132.838 94.074  110.641 1.00 41.09  ? 193 LEU E N   1 
ATOM   4232  C  CA  . LEU B 2 247 ? 132.371 94.412  109.303 1.00 35.77  ? 193 LEU E CA  1 
ATOM   4233  C  C   . LEU B 2 247 ? 131.172 93.544  108.963 1.00 40.32  ? 193 LEU E C   1 
ATOM   4234  O  O   . LEU B 2 247 ? 131.230 92.321  109.111 1.00 43.66  ? 193 LEU E O   1 
ATOM   4235  C  CB  . LEU B 2 247 ? 133.471 94.200  108.261 1.00 34.32  ? 193 LEU E CB  1 
ATOM   4236  C  CG  . LEU B 2 247 ? 134.869 94.719  108.581 1.00 38.47  ? 193 LEU E CG  1 
ATOM   4237  C  CD1 . LEU B 2 247 ? 135.830 94.359  107.477 1.00 38.22  ? 193 LEU E CD1 1 
ATOM   4238  C  CD2 . LEU B 2 247 ? 134.835 96.202  108.778 1.00 38.90  ? 193 LEU E CD2 1 
ATOM   4239  N  N   . VAL B 2 248 ? 130.090 94.172  108.506 1.00 44.09  ? 194 VAL E N   1 
ATOM   4240  C  CA  . VAL B 2 248 ? 128.866 93.463  108.153 1.00 44.29  ? 194 VAL E CA  1 
ATOM   4241  C  C   . VAL B 2 248 ? 128.428 93.897  106.762 1.00 43.65  ? 194 VAL E C   1 
ATOM   4242  O  O   . VAL B 2 248 ? 128.640 95.042  106.359 1.00 42.88  ? 194 VAL E O   1 
ATOM   4243  C  CB  . VAL B 2 248 ? 127.739 93.716  109.180 1.00 46.99  ? 194 VAL E CB  1 
ATOM   4244  C  CG1 . VAL B 2 248 ? 126.572 92.789  108.932 1.00 55.37  ? 194 VAL E CG1 1 
ATOM   4245  C  CG2 . VAL B 2 248 ? 128.254 93.540  110.588 1.00 50.07  ? 194 VAL E CG2 1 
ATOM   4246  N  N   . SER B 2 249 ? 127.820 92.971  106.024 1.00 43.30  ? 195 SER E N   1 
ATOM   4247  C  CA  . SER B 2 249 ? 127.278 93.251  104.702 1.00 43.94  ? 195 SER E CA  1 
ATOM   4248  C  C   . SER B 2 249 ? 125.894 92.632  104.586 1.00 51.46  ? 195 SER E C   1 
ATOM   4249  O  O   . SER B 2 249 ? 125.728 91.442  104.862 1.00 62.87  ? 195 SER E O   1 
ATOM   4250  C  CB  . SER B 2 249 ? 128.196 92.701  103.612 1.00 39.32  ? 195 SER E CB  1 
ATOM   4251  O  OG  . SER B 2 249 ? 127.690 92.992  102.326 1.00 44.80  ? 195 SER E OG  1 
ATOM   4252  N  N   . ARG B 2 250 ? 124.908 93.422  104.166 1.00 47.16  ? 196 ARG E N   1 
ATOM   4253  C  CA  . ARG B 2 250 ? 123.532 92.938  104.109 1.00 48.59  ? 196 ARG E CA  1 
ATOM   4254  C  C   . ARG B 2 250 ? 122.747 93.762  103.092 1.00 49.46  ? 196 ARG E C   1 
ATOM   4255  O  O   . ARG B 2 250 ? 123.318 94.535  102.318 1.00 50.67  ? 196 ARG E O   1 
ATOM   4256  C  CB  . ARG B 2 250 ? 122.886 92.981  105.496 1.00 49.75  ? 196 ARG E CB  1 
ATOM   4257  C  CG  . ARG B 2 250 ? 122.792 94.363  106.094 1.00 48.22  ? 196 ARG E CG  1 
ATOM   4258  C  CD  . ARG B 2 250 ? 122.149 94.331  107.463 1.00 55.02  ? 196 ARG E CD  1 
ATOM   4259  N  NE  . ARG B 2 250 ? 122.048 95.667  108.035 1.00 65.39  ? 196 ARG E NE  1 
ATOM   4260  C  CZ  . ARG B 2 250 ? 120.929 96.373  108.105 1.00 62.85  ? 196 ARG E CZ  1 
ATOM   4261  N  NH1 . ARG B 2 250 ? 119.779 95.888  107.673 1.00 56.73  ? 196 ARG E NH1 1 
ATOM   4262  N  NH2 . ARG B 2 250 ? 120.962 97.591  108.631 1.00 61.51  ? 196 ARG E NH2 1 
ATOM   4263  N  N   . ASN B 2 251 ? 121.428 93.579  103.084 1.00 49.01  ? 197 ASN E N   1 
ATOM   4264  C  CA  . ASN B 2 251 ? 120.514 94.332  102.238 1.00 45.09  ? 197 ASN E CA  1 
ATOM   4265  C  C   . ASN B 2 251 ? 119.471 95.020  103.102 1.00 49.56  ? 197 ASN E C   1 
ATOM   4266  O  O   . ASN B 2 251 ? 118.957 94.430  104.055 1.00 57.88  ? 197 ASN E O   1 
ATOM   4267  C  CB  . ASN B 2 251 ? 119.808 93.428  101.228 1.00 42.83  ? 197 ASN E CB  1 
ATOM   4268  C  CG  . ASN B 2 251 ? 120.738 92.904  100.169 1.00 55.12  ? 197 ASN E CG  1 
ATOM   4269  O  OD1 . ASN B 2 251 ? 121.955 92.979  100.303 1.00 62.92  ? 197 ASN E OD1 1 
ATOM   4270  N  ND2 . ASN B 2 251 ? 120.171 92.364  99.102  1.00 56.94  ? 197 ASN E ND2 1 
ATOM   4271  N  N   . VAL B 2 252 ? 119.151 96.263  102.761 1.00 43.09  ? 198 VAL E N   1 
ATOM   4272  C  CA  . VAL B 2 252 ? 118.149 97.044  103.472 1.00 43.98  ? 198 VAL E CA  1 
ATOM   4273  C  C   . VAL B 2 252 ? 117.024 97.364  102.503 1.00 46.76  ? 198 VAL E C   1 
ATOM   4274  O  O   . VAL B 2 252 ? 117.274 97.836  101.391 1.00 50.26  ? 198 VAL E O   1 
ATOM   4275  C  CB  . VAL B 2 252 ? 118.742 98.332  104.065 1.00 42.08  ? 198 VAL E CB  1 
ATOM   4276  C  CG1 . VAL B 2 252 ? 117.687 99.085  104.829 1.00 41.05  ? 198 VAL E CG1 1 
ATOM   4277  C  CG2 . VAL B 2 252 ? 119.894 98.004  104.973 1.00 45.36  ? 198 VAL E CG2 1 
ATOM   4278  N  N   . VAL B 2 253 ? 115.792 97.109  102.922 1.00 45.13  ? 199 VAL E N   1 
ATOM   4279  C  CA  . VAL B 2 253 ? 114.622 97.268  102.070 1.00 42.66  ? 199 VAL E CA  1 
ATOM   4280  C  C   . VAL B 2 253 ? 113.882 98.531  102.476 1.00 50.62  ? 199 VAL E C   1 
ATOM   4281  O  O   . VAL B 2 253 ? 113.519 98.698  103.646 1.00 57.04  ? 199 VAL E O   1 
ATOM   4282  C  CB  . VAL B 2 253 ? 113.699 96.044  102.167 1.00 39.16  ? 199 VAL E CB  1 
ATOM   4283  C  CG1 . VAL B 2 253 ? 112.434 96.280  101.376 1.00 39.02  ? 199 VAL E CG1 1 
ATOM   4284  C  CG2 . VAL B 2 253 ? 114.415 94.809  101.673 1.00 38.22  ? 199 VAL E CG2 1 
ATOM   4285  N  N   . PHE B 2 254 ? 113.662 99.420  101.518 1.00 46.23  ? 200 PHE E N   1 
ATOM   4286  C  CA  . PHE B 2 254 ? 112.809 100.584 101.675 1.00 44.19  ? 200 PHE E CA  1 
ATOM   4287  C  C   . PHE B 2 254 ? 111.652 100.490 100.687 1.00 47.76  ? 200 PHE E C   1 
ATOM   4288  O  O   . PHE B 2 254 ? 111.589 99.584  99.852  1.00 47.76  ? 200 PHE E O   1 
ATOM   4289  C  CB  . PHE B 2 254 ? 113.593 101.880 101.458 1.00 42.16  ? 200 PHE E CB  1 
ATOM   4290  C  CG  . PHE B 2 254 ? 114.704 102.092 102.436 1.00 46.63  ? 200 PHE E CG  1 
ATOM   4291  C  CD1 . PHE B 2 254 ? 114.443 102.560 103.706 1.00 49.71  ? 200 PHE E CD1 1 
ATOM   4292  C  CD2 . PHE B 2 254 ? 116.012 101.846 102.079 1.00 45.48  ? 200 PHE E CD2 1 
ATOM   4293  C  CE1 . PHE B 2 254 ? 115.464 102.764 104.605 1.00 46.81  ? 200 PHE E CE1 1 
ATOM   4294  C  CE2 . PHE B 2 254 ? 117.035 102.052 102.974 1.00 46.22  ? 200 PHE E CE2 1 
ATOM   4295  C  CZ  . PHE B 2 254 ? 116.759 102.512 104.238 1.00 46.45  ? 200 PHE E CZ  1 
ATOM   4296  N  N   . ALA B 2 255 ? 110.752 101.475 100.756 1.00 47.22  ? 201 ALA E N   1 
ATOM   4297  C  CA  . ALA B 2 255 ? 109.570 101.469 99.904  1.00 40.75  ? 201 ALA E CA  1 
ATOM   4298  C  C   . ALA B 2 255 ? 109.919 101.554 98.427  1.00 44.94  ? 201 ALA E C   1 
ATOM   4299  O  O   . ALA B 2 255 ? 109.064 101.272 97.583  1.00 47.64  ? 201 ALA E O   1 
ATOM   4300  C  CB  . ALA B 2 255 ? 108.645 102.624 100.280 1.00 38.20  ? 201 ALA E CB  1 
ATOM   4301  N  N   . THR B 2 256 ? 111.148 101.940 98.097  1.00 43.60  ? 202 THR E N   1 
ATOM   4302  C  CA  . THR B 2 256 ? 111.599 102.043 96.720  1.00 38.33  ? 202 THR E CA  1 
ATOM   4303  C  C   . THR B 2 256 ? 112.418 100.844 96.258  1.00 42.13  ? 202 THR E C   1 
ATOM   4304  O  O   . THR B 2 256 ? 112.813 100.802 95.091  1.00 45.55  ? 202 THR E O   1 
ATOM   4305  C  CB  . THR B 2 256 ? 112.414 103.324 96.538  1.00 38.13  ? 202 THR E CB  1 
ATOM   4306  O  OG1 . THR B 2 256 ? 113.457 103.370 97.516  1.00 46.53  ? 202 THR E OG1 1 
ATOM   4307  C  CG2 . THR B 2 256 ? 111.534 104.533 96.714  1.00 34.19  ? 202 THR E CG2 1 
ATOM   4308  N  N   . GLY B 2 257 ? 112.688 99.876  97.129  1.00 41.25  ? 203 GLY E N   1 
ATOM   4309  C  CA  . GLY B 2 257 ? 113.378 98.675  96.714  1.00 37.63  ? 203 GLY E CA  1 
ATOM   4310  C  C   . GLY B 2 257 ? 114.422 98.265  97.726  1.00 43.83  ? 203 GLY E C   1 
ATOM   4311  O  O   . GLY B 2 257 ? 114.493 98.797  98.830  1.00 48.20  ? 203 GLY E O   1 
ATOM   4312  N  N   . ALA B 2 258 ? 115.255 97.305  97.332  1.00 45.91  ? 204 ALA E N   1 
ATOM   4313  C  CA  . ALA B 2 258 ? 116.291 96.746  98.190  1.00 42.40  ? 204 ALA E CA  1 
ATOM   4314  C  C   . ALA B 2 258 ? 117.653 97.290  97.782  1.00 43.16  ? 204 ALA E C   1 
ATOM   4315  O  O   . ALA B 2 258 ? 117.995 97.280  96.599  1.00 49.47  ? 204 ALA E O   1 
ATOM   4316  C  CB  . ALA B 2 258 ? 116.293 95.220  98.107  1.00 36.55  ? 204 ALA E CB  1 
ATOM   4317  N  N   . TYR B 2 259 ? 118.432 97.744  98.758  1.00 38.83  ? 205 TYR E N   1 
ATOM   4318  C  CA  . TYR B 2 259 ? 119.722 98.355  98.499  1.00 38.52  ? 205 TYR E CA  1 
ATOM   4319  C  C   . TYR B 2 259 ? 120.813 97.634  99.276  1.00 44.88  ? 205 TYR E C   1 
ATOM   4320  O  O   . TYR B 2 259 ? 120.545 97.056  100.332 1.00 50.71  ? 205 TYR E O   1 
ATOM   4321  C  CB  . TYR B 2 259 ? 119.718 99.836  98.894  1.00 37.75  ? 205 TYR E CB  1 
ATOM   4322  C  CG  . TYR B 2 259 ? 118.662 100.657 98.199  1.00 38.02  ? 205 TYR E CG  1 
ATOM   4323  C  CD1 . TYR B 2 259 ? 117.354 100.652 98.644  1.00 38.60  ? 205 TYR E CD1 1 
ATOM   4324  C  CD2 . TYR B 2 259 ? 118.977 101.448 97.108  1.00 36.75  ? 205 TYR E CD2 1 
ATOM   4325  C  CE1 . TYR B 2 259 ? 116.392 101.398 98.021  1.00 38.59  ? 205 TYR E CE1 1 
ATOM   4326  C  CE2 . TYR B 2 259 ? 118.016 102.196 96.480  1.00 37.54  ? 205 TYR E CE2 1 
ATOM   4327  C  CZ  . TYR B 2 259 ? 116.724 102.165 96.939  1.00 37.29  ? 205 TYR E CZ  1 
ATOM   4328  O  OH  . TYR B 2 259 ? 115.753 102.913 96.323  1.00 39.46  ? 205 TYR E OH  1 
ATOM   4329  N  N   . PRO B 2 260 ? 122.045 97.629  98.774  1.00 42.53  ? 206 PRO E N   1 
ATOM   4330  C  CA  . PRO B 2 260 ? 123.136 96.976  99.506  1.00 42.14  ? 206 PRO E CA  1 
ATOM   4331  C  C   . PRO B 2 260 ? 123.712 97.874  100.589 1.00 40.72  ? 206 PRO E C   1 
ATOM   4332  O  O   . PRO B 2 260 ? 123.859 99.084  100.410 1.00 42.74  ? 206 PRO E O   1 
ATOM   4333  C  CB  . PRO B 2 260 ? 124.166 96.697  98.410  1.00 40.25  ? 206 PRO E CB  1 
ATOM   4334  C  CG  . PRO B 2 260 ? 123.925 97.762  97.415  1.00 35.77  ? 206 PRO E CG  1 
ATOM   4335  C  CD  . PRO B 2 260 ? 122.454 98.012  97.415  1.00 37.45  ? 206 PRO E CD  1 
ATOM   4336  N  N   . ARG B 2 261 ? 124.057 97.265  101.720 1.00 38.52  ? 207 ARG E N   1 
ATOM   4337  C  CA  . ARG B 2 261 ? 124.518 97.993  102.890 1.00 38.97  ? 207 ARG E CA  1 
ATOM   4338  C  C   . ARG B 2 261 ? 125.780 97.351  103.437 1.00 41.95  ? 207 ARG E C   1 
ATOM   4339  O  O   . ARG B 2 261 ? 125.851 96.126  103.567 1.00 45.52  ? 207 ARG E O   1 
ATOM   4340  C  CB  . ARG B 2 261 ? 123.442 98.014  103.975 1.00 40.84  ? 207 ARG E CB  1 
ATOM   4341  C  CG  . ARG B 2 261 ? 123.936 98.490  105.319 1.00 43.93  ? 207 ARG E CG  1 
ATOM   4342  C  CD  . ARG B 2 261 ? 123.959 99.991  105.387 1.00 43.81  ? 207 ARG E CD  1 
ATOM   4343  N  NE  . ARG B 2 261 ? 122.624 100.542 105.212 1.00 48.71  ? 207 ARG E NE  1 
ATOM   4344  C  CZ  . ARG B 2 261 ? 121.760 100.734 106.197 1.00 50.25  ? 207 ARG E CZ  1 
ATOM   4345  N  NH1 . ARG B 2 261 ? 122.062 100.433 107.446 1.00 52.23  ? 207 ARG E NH1 1 
ATOM   4346  N  NH2 . ARG B 2 261 ? 120.564 101.239 105.920 1.00 44.39  ? 207 ARG E NH2 1 
ATOM   4347  N  N   . LEU B 2 262 ? 126.767 98.181  103.761 1.00 37.53  ? 208 LEU E N   1 
ATOM   4348  C  CA  . LEU B 2 262 ? 127.942 97.773  104.512 1.00 33.12  ? 208 LEU E CA  1 
ATOM   4349  C  C   . LEU B 2 262 ? 127.943 98.511  105.842 1.00 38.28  ? 208 LEU E C   1 
ATOM   4350  O  O   . LEU B 2 262 ? 127.511 99.660  105.919 1.00 41.85  ? 208 LEU E O   1 
ATOM   4351  C  CB  . LEU B 2 262 ? 129.227 98.071  103.742 1.00 30.51  ? 208 LEU E CB  1 
ATOM   4352  C  CG  . LEU B 2 262 ? 129.385 97.443  102.357 1.00 30.86  ? 208 LEU E CG  1 
ATOM   4353  C  CD1 . LEU B 2 262 ? 130.639 97.935  101.675 1.00 32.47  ? 208 LEU E CD1 1 
ATOM   4354  C  CD2 . LEU B 2 262 ? 129.398 95.940  102.450 1.00 32.33  ? 208 LEU E CD2 1 
ATOM   4355  N  N   . SER B 2 263 ? 128.409 97.851  106.895 1.00 38.55  ? 209 SER E N   1 
ATOM   4356  C  CA  . SER B 2 263 ? 128.428 98.438  108.225 1.00 34.96  ? 209 SER E CA  1 
ATOM   4357  C  C   . SER B 2 263 ? 129.779 98.197  108.871 1.00 36.93  ? 209 SER E C   1 
ATOM   4358  O  O   . SER B 2 263 ? 130.239 97.055  108.947 1.00 40.99  ? 209 SER E O   1 
ATOM   4359  C  CB  . SER B 2 263 ? 127.328 97.860  109.113 1.00 42.63  ? 209 SER E CB  1 
ATOM   4360  O  OG  . SER B 2 263 ? 126.048 98.313  108.718 1.00 56.44  ? 209 SER E OG  1 
ATOM   4361  N  N   . LEU B 2 264 ? 130.397 99.271  109.347 1.00 35.77  ? 210 LEU E N   1 
ATOM   4362  C  CA  . LEU B 2 264 ? 131.654 99.201  110.080 1.00 35.42  ? 210 LEU E CA  1 
ATOM   4363  C  C   . LEU B 2 264 ? 131.397 99.672  111.501 1.00 41.26  ? 210 LEU E C   1 
ATOM   4364  O  O   . LEU B 2 264 ? 131.042 100.832 111.709 1.00 44.72  ? 210 LEU E O   1 
ATOM   4365  C  CB  . LEU B 2 264 ? 132.721 100.067 109.409 1.00 33.32  ? 210 LEU E CB  1 
ATOM   4366  C  CG  . LEU B 2 264 ? 133.903 100.506 110.266 1.00 35.75  ? 210 LEU E CG  1 
ATOM   4367  C  CD1 . LEU B 2 264 ? 134.796 99.329  110.597 1.00 37.79  ? 210 LEU E CD1 1 
ATOM   4368  C  CD2 . LEU B 2 264 ? 134.682 101.595 109.558 1.00 33.08  ? 210 LEU E CD2 1 
ATOM   4369  N  N   . SER B 2 265 ? 131.567 98.785  112.477 1.00 41.97  ? 211 SER E N   1 
ATOM   4370  C  CA  . SER B 2 265 ? 131.222 99.106  113.855 1.00 38.77  ? 211 SER E CA  1 
ATOM   4371  C  C   . SER B 2 265 ? 132.421 98.932  114.773 1.00 39.77  ? 211 SER E C   1 
ATOM   4372  O  O   . SER B 2 265 ? 133.231 98.025  114.581 1.00 46.51  ? 211 SER E O   1 
ATOM   4373  C  CB  . SER B 2 265 ? 130.069 98.233  114.335 1.00 42.40  ? 211 SER E CB  1 
ATOM   4374  O  OG  . SER B 2 265 ? 130.325 96.870  114.070 1.00 49.18  ? 211 SER E OG  1 
ATOM   4375  N  N   . PHE B 2 266 ? 132.529 99.809  115.767 1.00 40.04  ? 212 PHE E N   1 
ATOM   4376  C  CA  . PHE B 2 266 ? 133.544 99.730  116.807 1.00 38.71  ? 212 PHE E CA  1 
ATOM   4377  C  C   . PHE B 2 266 ? 132.861 99.626  118.159 1.00 41.85  ? 212 PHE E C   1 
ATOM   4378  O  O   . PHE B 2 266 ? 131.890 100.340 118.428 1.00 48.13  ? 212 PHE E O   1 
ATOM   4379  C  CB  . PHE B 2 266 ? 134.458 100.959 116.832 1.00 36.08  ? 212 PHE E CB  1 
ATOM   4380  C  CG  . PHE B 2 266 ? 134.767 101.527 115.487 1.00 46.94  ? 212 PHE E CG  1 
ATOM   4381  C  CD1 . PHE B 2 266 ? 133.919 102.446 114.900 1.00 45.11  ? 212 PHE E CD1 1 
ATOM   4382  C  CD2 . PHE B 2 266 ? 135.919 101.169 114.822 1.00 49.66  ? 212 PHE E CD2 1 
ATOM   4383  C  CE1 . PHE B 2 266 ? 134.203 102.975 113.668 1.00 42.05  ? 212 PHE E CE1 1 
ATOM   4384  C  CE2 . PHE B 2 266 ? 136.209 101.699 113.589 1.00 49.57  ? 212 PHE E CE2 1 
ATOM   4385  C  CZ  . PHE B 2 266 ? 135.351 102.604 113.013 1.00 48.25  ? 212 PHE E CZ  1 
ATOM   4386  N  N   . ARG B 2 267 ? 133.383 98.755  119.018 1.00 43.71  ? 213 ARG E N   1 
ATOM   4387  C  CA  . ARG B 2 267 ? 132.931 98.660  120.402 1.00 46.36  ? 213 ARG E CA  1 
ATOM   4388  C  C   . ARG B 2 267 ? 133.931 99.404  121.279 1.00 46.57  ? 213 ARG E C   1 
ATOM   4389  O  O   . ARG B 2 267 ? 135.074 98.970  121.440 1.00 48.12  ? 213 ARG E O   1 
ATOM   4390  C  CB  . ARG B 2 267 ? 132.774 97.207  120.843 1.00 47.89  ? 213 ARG E CB  1 
ATOM   4391  C  CG  . ARG B 2 267 ? 131.907 97.061  122.081 1.00 51.84  ? 213 ARG E CG  1 
ATOM   4392  C  CD  . ARG B 2 267 ? 131.440 95.638  122.321 1.00 60.49  ? 213 ARG E CD  1 
ATOM   4393  N  NE  . ARG B 2 267 ? 132.492 94.796  122.873 1.00 73.11  ? 213 ARG E NE  1 
ATOM   4394  C  CZ  . ARG B 2 267 ? 133.080 93.806  122.217 1.00 81.05  ? 213 ARG E CZ  1 
ATOM   4395  N  NH1 . ARG B 2 267 ? 132.728 93.492  120.982 1.00 82.09  ? 213 ARG E NH1 1 
ATOM   4396  N  NH2 . ARG B 2 267 ? 134.040 93.111  122.817 1.00 78.81  ? 213 ARG E NH2 1 
ATOM   4397  N  N   . LEU B 2 268 ? 133.494 100.521 121.842 1.00 47.04  ? 214 LEU E N   1 
ATOM   4398  C  CA  . LEU B 2 268 ? 134.336 101.411 122.625 1.00 47.51  ? 214 LEU E CA  1 
ATOM   4399  C  C   . LEU B 2 268 ? 134.133 101.158 124.112 1.00 55.06  ? 214 LEU E C   1 
ATOM   4400  O  O   . LEU B 2 268 ? 133.009 100.941 124.567 1.00 59.46  ? 214 LEU E O   1 
ATOM   4401  C  CB  . LEU B 2 268 ? 134.014 102.869 122.303 1.00 44.55  ? 214 LEU E CB  1 
ATOM   4402  C  CG  . LEU B 2 268 ? 134.876 103.624 121.295 1.00 47.29  ? 214 LEU E CG  1 
ATOM   4403  C  CD1 . LEU B 2 268 ? 135.107 102.822 120.038 1.00 45.96  ? 214 LEU E CD1 1 
ATOM   4404  C  CD2 . LEU B 2 268 ? 134.206 104.934 120.960 1.00 44.72  ? 214 LEU E CD2 1 
ATOM   4405  N  N   . LYS B 2 269 ? 135.227 101.181 124.864 1.00 58.04  ? 215 LYS E N   1 
ATOM   4406  C  CA  . LYS B 2 269 ? 135.199 101.036 126.311 1.00 59.09  ? 215 LYS E CA  1 
ATOM   4407  C  C   . LYS B 2 269 ? 135.865 102.248 126.941 1.00 62.04  ? 215 LYS E C   1 
ATOM   4408  O  O   . LYS B 2 269 ? 136.911 102.701 126.473 1.00 65.86  ? 215 LYS E O   1 
ATOM   4409  C  CB  . LYS B 2 269 ? 135.906 99.757  126.753 1.00 59.43  ? 215 LYS E CB  1 
ATOM   4410  C  CG  . LYS B 2 269 ? 135.728 99.440  128.217 1.00 65.50  ? 215 LYS E CG  1 
ATOM   4411  C  CD  . LYS B 2 269 ? 136.253 98.062  128.549 1.00 72.57  ? 215 LYS E CD  1 
ATOM   4412  C  CE  . LYS B 2 269 ? 135.884 97.670  129.968 1.00 82.69  ? 215 LYS E CE  1 
ATOM   4413  N  NZ  . LYS B 2 269 ? 134.409 97.689  130.170 1.00 83.58  ? 215 LYS E NZ  1 
ATOM   4414  N  N   . ARG B 2 270 ? 135.258 102.776 127.998 1.00 60.00  ? 216 ARG E N   1 
ATOM   4415  C  CA  . ARG B 2 270 ? 135.717 104.022 128.594 1.00 62.67  ? 216 ARG E CA  1 
ATOM   4416  C  C   . ARG B 2 270 ? 136.757 103.747 129.671 1.00 65.28  ? 216 ARG E C   1 
ATOM   4417  O  O   . ARG B 2 270 ? 136.544 102.907 130.549 1.00 65.78  ? 216 ARG E O   1 
ATOM   4418  C  CB  . ARG B 2 270 ? 134.543 104.802 129.181 1.00 58.92  ? 216 ARG E CB  1 
ATOM   4419  C  CG  . ARG B 2 270 ? 134.878 106.237 129.519 1.00 56.81  ? 216 ARG E CG  1 
ATOM   4420  C  CD  . ARG B 2 270 ? 133.692 106.934 130.129 1.00 57.88  ? 216 ARG E CD  1 
ATOM   4421  N  NE  . ARG B 2 270 ? 132.506 106.817 129.292 1.00 59.02  ? 216 ARG E NE  1 
ATOM   4422  C  CZ  . ARG B 2 270 ? 132.106 107.739 128.429 1.00 61.30  ? 216 ARG E CZ  1 
ATOM   4423  N  NH1 . ARG B 2 270 ? 132.774 108.868 128.265 1.00 59.18  ? 216 ARG E NH1 1 
ATOM   4424  N  NH2 . ARG B 2 270 ? 131.007 107.523 127.713 1.00 63.14  ? 216 ARG E NH2 1 
ATOM   4425  N  N   . ASN B 2 271 ? 137.882 104.454 129.595 1.00 63.54  ? 217 ASN E N   1 
ATOM   4426  C  CA  . ASN B 2 271 ? 138.920 104.322 130.606 1.00 63.86  ? 217 ASN E CA  1 
ATOM   4427  C  C   . ASN B 2 271 ? 138.498 105.004 131.898 1.00 67.94  ? 217 ASN E C   1 
ATOM   4428  O  O   . ASN B 2 271 ? 137.906 106.085 131.886 1.00 71.16  ? 217 ASN E O   1 
ATOM   4429  C  CB  . ASN B 2 271 ? 140.231 104.921 130.110 1.00 64.79  ? 217 ASN E CB  1 
ATOM   4430  C  CG  . ASN B 2 271 ? 140.811 104.154 128.951 1.00 70.62  ? 217 ASN E CG  1 
ATOM   4431  O  OD1 . ASN B 2 271 ? 140.513 102.977 128.761 1.00 70.84  ? 217 ASN E OD1 1 
ATOM   4432  N  ND2 . ASN B 2 271 ? 141.648 104.816 128.165 1.00 66.72  ? 217 ASN E ND2 1 
ATOM   4433  N  N   . ILE B 2 272 ? 138.826 104.369 133.025 1.00 70.26  ? 218 ILE E N   1 
ATOM   4434  C  CA  . ILE B 2 272 ? 138.401 104.848 134.331 1.00 65.95  ? 218 ILE E CA  1 
ATOM   4435  C  C   . ILE B 2 272 ? 139.487 105.632 135.049 1.00 67.10  ? 218 ILE E C   1 
ATOM   4436  O  O   . ILE B 2 272 ? 139.255 106.120 136.160 1.00 72.76  ? 218 ILE E O   1 
ATOM   4437  C  CB  . ILE B 2 272 ? 137.921 103.674 135.202 1.00 61.62  ? 218 ILE E CB  1 
ATOM   4438  C  CG1 . ILE B 2 272 ? 136.898 104.154 136.230 1.00 66.03  ? 218 ILE E CG1 1 
ATOM   4439  C  CG2 . ILE B 2 272 ? 139.099 102.998 135.871 1.00 63.98  ? 218 ILE E CG2 1 
ATOM   4440  C  CD1 . ILE B 2 272 ? 136.404 103.065 137.131 1.00 67.36  ? 218 ILE E CD1 1 
ATOM   4441  N  N   . GLY B 2 273 ? 140.664 105.781 134.444 1.00 68.89  ? 219 GLY E N   1 
ATOM   4442  C  CA  . GLY B 2 273 ? 141.741 106.489 135.115 1.00 69.97  ? 219 GLY E CA  1 
ATOM   4443  C  C   . GLY B 2 273 ? 141.448 107.959 135.347 1.00 67.96  ? 219 GLY E C   1 
ATOM   4444  O  O   . GLY B 2 273 ? 141.681 108.479 136.443 1.00 72.61  ? 219 GLY E O   1 
ATOM   4445  N  N   . TYR B 2 274 ? 140.942 108.653 134.327 1.00 65.94  ? 220 TYR E N   1 
ATOM   4446  C  CA  . TYR B 2 274 ? 140.747 110.093 134.457 1.00 71.61  ? 220 TYR E CA  1 
ATOM   4447  C  C   . TYR B 2 274 ? 139.707 110.414 135.518 1.00 73.31  ? 220 TYR E C   1 
ATOM   4448  O  O   . TYR B 2 274 ? 139.876 111.353 136.302 1.00 69.93  ? 220 TYR E O   1 
ATOM   4449  C  CB  . TYR B 2 274 ? 140.341 110.714 133.121 1.00 72.15  ? 220 TYR E CB  1 
ATOM   4450  C  CG  . TYR B 2 274 ? 139.735 112.090 133.291 1.00 73.72  ? 220 TYR E CG  1 
ATOM   4451  C  CD1 . TYR B 2 274 ? 140.468 113.128 133.843 1.00 71.89  ? 220 TYR E CD1 1 
ATOM   4452  C  CD2 . TYR B 2 274 ? 138.425 112.345 132.914 1.00 75.91  ? 220 TYR E CD2 1 
ATOM   4453  C  CE1 . TYR B 2 274 ? 139.918 114.378 134.009 1.00 73.17  ? 220 TYR E CE1 1 
ATOM   4454  C  CE2 . TYR B 2 274 ? 137.866 113.594 133.078 1.00 73.98  ? 220 TYR E CE2 1 
ATOM   4455  C  CZ  . TYR B 2 274 ? 138.616 114.605 133.627 1.00 72.62  ? 220 TYR E CZ  1 
ATOM   4456  O  OH  . TYR B 2 274 ? 138.063 115.851 133.790 1.00 71.93  ? 220 TYR E OH  1 
ATOM   4457  N  N   . PHE B 2 275 ? 138.617 109.652 135.550 1.00 72.96  ? 221 PHE E N   1 
ATOM   4458  C  CA  . PHE B 2 275 ? 137.563 109.929 136.516 1.00 68.36  ? 221 PHE E CA  1 
ATOM   4459  C  C   . PHE B 2 275 ? 138.025 109.659 137.936 1.00 68.77  ? 221 PHE E C   1 
ATOM   4460  O  O   . PHE B 2 275 ? 137.629 110.372 138.862 1.00 72.05  ? 221 PHE E O   1 
ATOM   4461  C  CB  . PHE B 2 275 ? 136.331 109.108 136.170 1.00 65.42  ? 221 PHE E CB  1 
ATOM   4462  C  CG  . PHE B 2 275 ? 135.928 109.236 134.740 1.00 70.03  ? 221 PHE E CG  1 
ATOM   4463  C  CD1 . PHE B 2 275 ? 135.318 110.390 134.285 1.00 65.59  ? 221 PHE E CD1 1 
ATOM   4464  C  CD2 . PHE B 2 275 ? 136.182 108.221 133.840 1.00 71.76  ? 221 PHE E CD2 1 
ATOM   4465  C  CE1 . PHE B 2 275 ? 134.955 110.524 132.964 1.00 63.95  ? 221 PHE E CE1 1 
ATOM   4466  C  CE2 . PHE B 2 275 ? 135.817 108.350 132.517 1.00 72.04  ? 221 PHE E CE2 1 
ATOM   4467  C  CZ  . PHE B 2 275 ? 135.202 109.504 132.081 1.00 69.05  ? 221 PHE E CZ  1 
ATOM   4468  N  N   . ILE B 2 276 ? 138.863 108.642 138.129 1.00 68.17  ? 222 ILE E N   1 
ATOM   4469  C  CA  . ILE B 2 276 ? 139.482 108.441 139.433 1.00 66.14  ? 222 ILE E CA  1 
ATOM   4470  C  C   . ILE B 2 276 ? 140.339 109.644 139.794 1.00 66.35  ? 222 ILE E C   1 
ATOM   4471  O  O   . ILE B 2 276 ? 140.216 110.210 140.883 1.00 68.59  ? 222 ILE E O   1 
ATOM   4472  C  CB  . ILE B 2 276 ? 140.308 107.145 139.444 1.00 62.69  ? 222 ILE E CB  1 
ATOM   4473  C  CG1 . ILE B 2 276 ? 139.400 105.928 139.284 1.00 63.09  ? 222 ILE E CG1 1 
ATOM   4474  C  CG2 . ILE B 2 276 ? 141.111 107.046 140.723 1.00 64.43  ? 222 ILE E CG2 1 
ATOM   4475  C  CD1 . ILE B 2 276 ? 138.432 105.735 140.412 1.00 65.89  ? 222 ILE E CD1 1 
ATOM   4476  N  N   . LEU B 2 277 ? 141.198 110.076 138.872 1.00 67.86  ? 223 LEU E N   1 
ATOM   4477  C  CA  . LEU B 2 277 ? 142.103 111.177 139.173 1.00 70.54  ? 223 LEU E CA  1 
ATOM   4478  C  C   . LEU B 2 277 ? 141.394 112.511 139.358 1.00 69.76  ? 223 LEU E C   1 
ATOM   4479  O  O   . LEU B 2 277 ? 141.959 113.410 139.987 1.00 71.00  ? 223 LEU E O   1 
ATOM   4480  C  CB  . LEU B 2 277 ? 143.150 111.317 138.068 1.00 71.00  ? 223 LEU E CB  1 
ATOM   4481  C  CG  . LEU B 2 277 ? 144.312 110.328 138.096 1.00 66.07  ? 223 LEU E CG  1 
ATOM   4482  C  CD1 . LEU B 2 277 ? 145.073 110.390 136.795 1.00 65.71  ? 223 LEU E CD1 1 
ATOM   4483  C  CD2 . LEU B 2 277 ? 145.230 110.628 139.266 1.00 60.31  ? 223 LEU E CD2 1 
ATOM   4484  N  N   . GLN B 2 278 ? 140.181 112.657 138.847 1.00 71.63  ? 224 GLN E N   1 
ATOM   4485  C  CA  . GLN B 2 278 ? 139.500 113.943 138.800 1.00 73.40  ? 224 GLN E CA  1 
ATOM   4486  C  C   . GLN B 2 278 ? 138.298 114.033 139.720 1.00 74.35  ? 224 GLN E C   1 
ATOM   4487  O  O   . GLN B 2 278 ? 138.123 115.048 140.395 1.00 75.05  ? 224 GLN E O   1 
ATOM   4488  C  CB  . GLN B 2 278 ? 139.045 114.233 137.369 1.00 74.85  ? 224 GLN E CB  1 
ATOM   4489  C  CG  . GLN B 2 278 ? 138.176 115.465 137.239 1.00 76.02  ? 224 GLN E CG  1 
ATOM   4490  C  CD  . GLN B 2 278 ? 138.909 116.729 137.618 1.00 85.53  ? 224 GLN E CD  1 
ATOM   4491  O  OE1 . GLN B 2 278 ? 140.130 116.815 137.492 1.00 88.35  ? 224 GLN E OE1 1 
ATOM   4492  N  NE2 . GLN B 2 278 ? 138.167 117.720 138.091 1.00 88.35  ? 224 GLN E NE2 1 
ATOM   4493  N  N   . THR B 2 279 ? 137.461 113.000 139.768 1.00 73.41  ? 225 THR E N   1 
ATOM   4494  C  CA  . THR B 2 279 ? 136.201 113.061 140.493 1.00 67.29  ? 225 THR E CA  1 
ATOM   4495  C  C   . THR B 2 279 ? 136.196 112.186 141.739 1.00 65.28  ? 225 THR E C   1 
ATOM   4496  O  O   . THR B 2 279 ? 135.999 112.692 142.845 1.00 68.26  ? 225 THR E O   1 
ATOM   4497  C  CB  . THR B 2 279 ? 135.051 112.651 139.572 1.00 72.80  ? 225 THR E CB  1 
ATOM   4498  O  OG1 . THR B 2 279 ? 135.042 113.491 138.414 1.00 77.87  ? 225 THR E OG1 1 
ATOM   4499  C  CG2 . THR B 2 279 ? 133.734 112.783 140.299 1.00 73.40  ? 225 THR E CG2 1 
ATOM   4500  N  N   . TYR B 2 280 ? 136.410 110.881 141.588 1.00 62.67  ? 226 TYR E N   1 
ATOM   4501  C  CA  . TYR B 2 280 ? 136.214 109.972 142.710 1.00 62.25  ? 226 TYR E CA  1 
ATOM   4502  C  C   . TYR B 2 280 ? 137.220 110.229 143.824 1.00 63.26  ? 226 TYR E C   1 
ATOM   4503  O  O   . TYR B 2 280 ? 136.844 110.336 144.996 1.00 64.60  ? 226 TYR E O   1 
ATOM   4504  C  CB  . TYR B 2 280 ? 136.297 108.527 142.232 1.00 65.30  ? 226 TYR E CB  1 
ATOM   4505  C  CG  . TYR B 2 280 ? 135.078 108.076 141.469 1.00 75.32  ? 226 TYR E CG  1 
ATOM   4506  C  CD1 . TYR B 2 280 ? 133.903 107.773 142.131 1.00 79.30  ? 226 TYR E CD1 1 
ATOM   4507  C  CD2 . TYR B 2 280 ? 135.103 107.945 140.089 1.00 76.73  ? 226 TYR E CD2 1 
ATOM   4508  C  CE1 . TYR B 2 280 ? 132.787 107.358 141.446 1.00 80.46  ? 226 TYR E CE1 1 
ATOM   4509  C  CE2 . TYR B 2 280 ? 133.988 107.531 139.395 1.00 73.74  ? 226 TYR E CE2 1 
ATOM   4510  C  CZ  . TYR B 2 280 ? 132.833 107.238 140.081 1.00 73.05  ? 226 TYR E CZ  1 
ATOM   4511  O  OH  . TYR B 2 280 ? 131.715 106.823 139.404 1.00 75.31  ? 226 TYR E OH  1 
ATOM   4512  N  N   . MET B 2 281 ? 138.502 110.314 143.485 1.00 61.16  ? 227 MET E N   1 
ATOM   4513  C  CA  . MET B 2 281 ? 139.517 110.502 144.518 1.00 58.66  ? 227 MET E CA  1 
ATOM   4514  C  C   . MET B 2 281 ? 139.356 111.820 145.266 1.00 59.76  ? 227 MET E C   1 
ATOM   4515  O  O   . MET B 2 281 ? 139.441 111.809 146.505 1.00 61.36  ? 227 MET E O   1 
ATOM   4516  C  CB  . MET B 2 281 ? 140.911 110.359 143.903 1.00 64.08  ? 227 MET E CB  1 
ATOM   4517  C  CG  . MET B 2 281 ? 142.015 110.104 144.907 1.00 75.51  ? 227 MET E CG  1 
ATOM   4518  S  SD  . MET B 2 281 ? 143.516 109.493 144.116 1.00 98.75  ? 227 MET E SD  1 
ATOM   4519  C  CE  . MET B 2 281 ? 144.523 109.122 145.545 1.00 72.35  ? 227 MET E CE  1 
ATOM   4520  N  N   . PRO B 2 282 ? 139.144 112.971 144.612 1.00 57.98  ? 228 PRO E N   1 
ATOM   4521  C  CA  . PRO B 2 282 ? 138.877 114.191 145.391 1.00 58.52  ? 228 PRO E CA  1 
ATOM   4522  C  C   . PRO B 2 282 ? 137.633 114.111 146.255 1.00 59.91  ? 228 PRO E C   1 
ATOM   4523  O  O   . PRO B 2 282 ? 137.646 114.609 147.386 1.00 60.09  ? 228 PRO E O   1 
ATOM   4524  C  CB  . PRO B 2 282 ? 138.745 115.266 144.308 1.00 59.25  ? 228 PRO E CB  1 
ATOM   4525  C  CG  . PRO B 2 282 ? 139.551 114.758 143.194 1.00 58.85  ? 228 PRO E CG  1 
ATOM   4526  C  CD  . PRO B 2 282 ? 139.314 113.286 143.184 1.00 59.42  ? 228 PRO E CD  1 
ATOM   4527  N  N   . SER B 2 283 ? 136.554 113.503 145.759 1.00 57.80  ? 229 SER E N   1 
ATOM   4528  C  CA  . SER B 2 283 ? 135.340 113.394 146.561 1.00 52.10  ? 229 SER E CA  1 
ATOM   4529  C  C   . SER B 2 283 ? 135.573 112.541 147.798 1.00 53.50  ? 229 SER E C   1 
ATOM   4530  O  O   . SER B 2 283 ? 135.149 112.905 148.901 1.00 60.62  ? 229 SER E O   1 
ATOM   4531  C  CB  . SER B 2 283 ? 134.206 112.816 145.723 1.00 56.56  ? 229 SER E CB  1 
ATOM   4532  O  OG  . SER B 2 283 ? 133.823 113.719 144.706 1.00 64.56  ? 229 SER E OG  1 
ATOM   4533  N  N   . ILE B 2 284 ? 136.253 111.407 147.638 1.00 50.17  ? 230 ILE E N   1 
ATOM   4534  C  CA  . ILE B 2 284 ? 136.566 110.565 148.787 1.00 53.66  ? 230 ILE E CA  1 
ATOM   4535  C  C   . ILE B 2 284 ? 137.478 111.303 149.754 1.00 54.35  ? 230 ILE E C   1 
ATOM   4536  O  O   . ILE B 2 284 ? 137.303 111.227 150.975 1.00 54.97  ? 230 ILE E O   1 
ATOM   4537  C  CB  . ILE B 2 284 ? 137.189 109.237 148.323 1.00 56.91  ? 230 ILE E CB  1 
ATOM   4538  C  CG1 . ILE B 2 284 ? 136.189 108.460 147.475 1.00 61.02  ? 230 ILE E CG1 1 
ATOM   4539  C  CG2 . ILE B 2 284 ? 137.619 108.405 149.508 1.00 52.65  ? 230 ILE E CG2 1 
ATOM   4540  C  CD1 . ILE B 2 284 ? 136.741 107.197 146.887 1.00 62.98  ? 230 ILE E CD1 1 
ATOM   4541  N  N   . LEU B 2 285 ? 138.467 112.027 149.229 1.00 51.56  ? 231 LEU E N   1 
ATOM   4542  C  CA  . LEU B 2 285 ? 139.384 112.747 150.101 1.00 51.87  ? 231 LEU E CA  1 
ATOM   4543  C  C   . LEU B 2 285 ? 138.654 113.804 150.917 1.00 54.47  ? 231 LEU E C   1 
ATOM   4544  O  O   . LEU B 2 285 ? 138.893 113.940 152.119 1.00 54.84  ? 231 LEU E O   1 
ATOM   4545  C  CB  . LEU B 2 285 ? 140.502 113.381 149.278 1.00 55.03  ? 231 LEU E CB  1 
ATOM   4546  C  CG  . LEU B 2 285 ? 141.509 114.222 150.061 1.00 59.87  ? 231 LEU E CG  1 
ATOM   4547  C  CD1 . LEU B 2 285 ? 142.303 113.352 151.018 1.00 56.29  ? 231 LEU E CD1 1 
ATOM   4548  C  CD2 . LEU B 2 285 ? 142.433 114.959 149.118 1.00 59.92  ? 231 LEU E CD2 1 
ATOM   4549  N  N   . ILE B 2 286 ? 137.752 114.556 150.285 1.00 53.16  ? 232 ILE E N   1 
ATOM   4550  C  CA  . ILE B 2 286 ? 137.023 115.595 151.005 1.00 49.04  ? 232 ILE E CA  1 
ATOM   4551  C  C   . ILE B 2 286 ? 136.074 114.982 152.023 1.00 51.31  ? 232 ILE E C   1 
ATOM   4552  O  O   . ILE B 2 286 ? 135.944 115.477 153.148 1.00 52.87  ? 232 ILE E O   1 
ATOM   4553  C  CB  . ILE B 2 286 ? 136.276 116.506 150.019 1.00 42.24  ? 232 ILE E CB  1 
ATOM   4554  C  CG1 . ILE B 2 286 ? 137.265 117.225 149.113 1.00 44.17  ? 232 ILE E CG1 1 
ATOM   4555  C  CG2 . ILE B 2 286 ? 135.430 117.508 150.765 1.00 46.61  ? 232 ILE E CG2 1 
ATOM   4556  C  CD1 . ILE B 2 286 ? 136.596 118.025 148.045 1.00 54.28  ? 232 ILE E CD1 1 
ATOM   4557  N  N   . THR B 2 287 ? 135.392 113.899 151.649 1.00 50.21  ? 233 THR E N   1 
ATOM   4558  C  CA  . THR B 2 287 ? 134.484 113.251 152.585 1.00 46.79  ? 233 THR E CA  1 
ATOM   4559  C  C   . THR B 2 287 ? 135.233 112.720 153.799 1.00 51.99  ? 233 THR E C   1 
ATOM   4560  O  O   . THR B 2 287 ? 134.750 112.833 154.930 1.00 56.13  ? 233 THR E O   1 
ATOM   4561  C  CB  . THR B 2 287 ? 133.724 112.135 151.880 1.00 49.05  ? 233 THR E CB  1 
ATOM   4562  O  OG1 . THR B 2 287 ? 133.023 112.684 150.761 1.00 52.69  ? 233 THR E OG1 1 
ATOM   4563  C  CG2 . THR B 2 287 ? 132.725 111.506 152.814 1.00 52.26  ? 233 THR E CG2 1 
ATOM   4564  N  N   . ILE B 2 288 ? 136.415 112.140 153.590 1.00 50.86  ? 234 ILE E N   1 
ATOM   4565  C  CA  . ILE B 2 288 ? 137.212 111.669 154.718 1.00 52.70  ? 234 ILE E CA  1 
ATOM   4566  C  C   . ILE B 2 288 ? 137.707 112.842 155.553 1.00 55.50  ? 234 ILE E C   1 
ATOM   4567  O  O   . ILE B 2 288 ? 137.674 112.800 156.787 1.00 57.74  ? 234 ILE E O   1 
ATOM   4568  C  CB  . ILE B 2 288 ? 138.379 110.799 154.222 1.00 52.19  ? 234 ILE E CB  1 
ATOM   4569  C  CG1 . ILE B 2 288 ? 137.852 109.524 153.574 1.00 56.09  ? 234 ILE E CG1 1 
ATOM   4570  C  CG2 . ILE B 2 288 ? 139.300 110.447 155.363 1.00 46.85  ? 234 ILE E CG2 1 
ATOM   4571  C  CD1 . ILE B 2 288 ? 138.931 108.675 152.967 1.00 53.43  ? 234 ILE E CD1 1 
ATOM   4572  N  N   . LEU B 2 289 ? 138.166 113.908 154.898 1.00 54.38  ? 235 LEU E N   1 
ATOM   4573  C  CA  . LEU B 2 289 ? 138.695 115.057 155.619 1.00 51.85  ? 235 LEU E CA  1 
ATOM   4574  C  C   . LEU B 2 289 ? 137.626 115.738 156.458 1.00 51.56  ? 235 LEU E C   1 
ATOM   4575  O  O   . LEU B 2 289 ? 137.941 116.337 157.490 1.00 53.78  ? 235 LEU E O   1 
ATOM   4576  C  CB  . LEU B 2 289 ? 139.311 116.047 154.632 1.00 50.07  ? 235 LEU E CB  1 
ATOM   4577  C  CG  . LEU B 2 289 ? 139.829 117.370 155.190 1.00 46.55  ? 235 LEU E CG  1 
ATOM   4578  C  CD1 . LEU B 2 289 ? 140.959 117.133 156.168 1.00 49.77  ? 235 LEU E CD1 1 
ATOM   4579  C  CD2 . LEU B 2 289 ? 140.271 118.269 154.062 1.00 43.08  ? 235 LEU E CD2 1 
ATOM   4580  N  N   . SER B 2 290 ? 136.363 115.665 156.040 1.00 49.43  ? 236 SER E N   1 
ATOM   4581  C  CA  . SER B 2 290 ? 135.307 116.255 156.852 1.00 47.52  ? 236 SER E CA  1 
ATOM   4582  C  C   . SER B 2 290 ? 135.126 115.528 158.175 1.00 49.56  ? 236 SER E C   1 
ATOM   4583  O  O   . SER B 2 290 ? 134.506 116.079 159.086 1.00 54.34  ? 236 SER E O   1 
ATOM   4584  C  CB  . SER B 2 290 ? 133.986 116.270 156.090 1.00 45.98  ? 236 SER E CB  1 
ATOM   4585  O  OG  . SER B 2 290 ? 133.422 114.977 156.036 1.00 55.44  ? 236 SER E OG  1 
ATOM   4586  N  N   . TRP B 2 291 ? 135.649 114.311 158.304 1.00 47.14  ? 237 TRP E N   1 
ATOM   4587  C  CA  . TRP B 2 291 ? 135.531 113.561 159.544 1.00 49.09  ? 237 TRP E CA  1 
ATOM   4588  C  C   . TRP B 2 291 ? 136.537 113.994 160.597 1.00 53.32  ? 237 TRP E C   1 
ATOM   4589  O  O   . TRP B 2 291 ? 136.431 113.554 161.744 1.00 57.10  ? 237 TRP E O   1 
ATOM   4590  C  CB  . TRP B 2 291 ? 135.699 112.067 159.277 1.00 52.50  ? 237 TRP E CB  1 
ATOM   4591  C  CG  . TRP B 2 291 ? 134.712 111.519 158.309 1.00 55.66  ? 237 TRP E CG  1 
ATOM   4592  C  CD1 . TRP B 2 291 ? 133.534 112.084 157.932 1.00 54.91  ? 237 TRP E CD1 1 
ATOM   4593  C  CD2 . TRP B 2 291 ? 134.821 110.294 157.580 1.00 57.49  ? 237 TRP E CD2 1 
ATOM   4594  N  NE1 . TRP B 2 291 ? 132.898 111.287 157.019 1.00 58.59  ? 237 TRP E NE1 1 
ATOM   4595  C  CE2 . TRP B 2 291 ? 133.670 110.180 156.786 1.00 62.53  ? 237 TRP E CE2 1 
ATOM   4596  C  CE3 . TRP B 2 291 ? 135.780 109.282 157.524 1.00 54.74  ? 237 TRP E CE3 1 
ATOM   4597  C  CZ2 . TRP B 2 291 ? 133.452 109.098 155.949 1.00 61.16  ? 237 TRP E CZ2 1 
ATOM   4598  C  CZ3 . TRP B 2 291 ? 135.561 108.210 156.691 1.00 56.06  ? 237 TRP E CZ3 1 
ATOM   4599  C  CH2 . TRP B 2 291 ? 134.408 108.124 155.916 1.00 57.51  ? 237 TRP E CH2 1 
ATOM   4600  N  N   . VAL B 2 292 ? 137.507 114.838 160.239 1.00 51.01  ? 238 VAL E N   1 
ATOM   4601  C  CA  . VAL B 2 292 ? 138.481 115.314 161.210 1.00 49.20  ? 238 VAL E CA  1 
ATOM   4602  C  C   . VAL B 2 292 ? 137.811 116.129 162.304 1.00 52.94  ? 238 VAL E C   1 
ATOM   4603  O  O   . VAL B 2 292 ? 138.339 116.226 163.416 1.00 56.60  ? 238 VAL E O   1 
ATOM   4604  C  CB  . VAL B 2 292 ? 139.580 116.129 160.498 1.00 45.62  ? 238 VAL E CB  1 
ATOM   4605  C  CG1 . VAL B 2 292 ? 140.628 116.599 161.480 1.00 46.68  ? 238 VAL E CG1 1 
ATOM   4606  C  CG2 . VAL B 2 292 ? 140.230 115.298 159.427 1.00 44.86  ? 238 VAL E CG2 1 
ATOM   4607  N  N   . SER B 2 293 ? 136.635 116.695 162.026 1.00 52.63  ? 239 SER E N   1 
ATOM   4608  C  CA  . SER B 2 293 ? 135.955 117.522 163.016 1.00 56.25  ? 239 SER E CA  1 
ATOM   4609  C  C   . SER B 2 293 ? 135.665 116.742 164.289 1.00 59.51  ? 239 SER E C   1 
ATOM   4610  O  O   . SER B 2 293 ? 135.850 117.259 165.395 1.00 66.87  ? 239 SER E O   1 
ATOM   4611  C  CB  . SER B 2 293 ? 134.660 118.077 162.431 1.00 55.18  ? 239 SER E CB  1 
ATOM   4612  O  OG  . SER B 2 293 ? 134.930 118.969 161.370 1.00 59.22  ? 239 SER E OG  1 
ATOM   4613  N  N   . PHE B 2 294 ? 135.223 115.493 164.160 1.00 58.46  ? 240 PHE E N   1 
ATOM   4614  C  CA  . PHE B 2 294 ? 134.860 114.728 165.342 1.00 62.27  ? 240 PHE E CA  1 
ATOM   4615  C  C   . PHE B 2 294 ? 136.057 114.455 166.242 1.00 65.69  ? 240 PHE E C   1 
ATOM   4616  O  O   . PHE B 2 294 ? 135.870 114.073 167.401 1.00 71.54  ? 240 PHE E O   1 
ATOM   4617  C  CB  . PHE B 2 294 ? 134.203 113.410 164.937 1.00 62.99  ? 240 PHE E CB  1 
ATOM   4618  C  CG  . PHE B 2 294 ? 133.234 113.533 163.799 1.00 60.65  ? 240 PHE E CG  1 
ATOM   4619  C  CD1 . PHE B 2 294 ? 132.116 114.333 163.904 1.00 61.52  ? 240 PHE E CD1 1 
ATOM   4620  C  CD2 . PHE B 2 294 ? 133.431 112.826 162.633 1.00 56.24  ? 240 PHE E CD2 1 
ATOM   4621  C  CE1 . PHE B 2 294 ? 131.225 114.439 162.860 1.00 54.59  ? 240 PHE E CE1 1 
ATOM   4622  C  CE2 . PHE B 2 294 ? 132.543 112.926 161.590 1.00 54.09  ? 240 PHE E CE2 1 
ATOM   4623  C  CZ  . PHE B 2 294 ? 131.439 113.736 161.702 1.00 53.80  ? 240 PHE E CZ  1 
ATOM   4624  N  N   . TRP B 2 295 ? 137.278 114.637 165.738 1.00 64.81  ? 241 TRP E N   1 
ATOM   4625  C  CA  . TRP B 2 295 ? 138.496 114.422 166.505 1.00 65.63  ? 241 TRP E CA  1 
ATOM   4626  C  C   . TRP B 2 295 ? 139.105 115.722 167.013 1.00 65.04  ? 241 TRP E C   1 
ATOM   4627  O  O   . TRP B 2 295 ? 140.256 115.728 167.457 1.00 67.53  ? 241 TRP E O   1 
ATOM   4628  C  CB  . TRP B 2 295 ? 139.521 113.658 165.669 1.00 64.03  ? 241 TRP E CB  1 
ATOM   4629  C  CG  . TRP B 2 295 ? 139.421 112.178 165.816 1.00 70.49  ? 241 TRP E CG  1 
ATOM   4630  C  CD1 . TRP B 2 295 ? 140.015 111.410 166.771 1.00 71.16  ? 241 TRP E CD1 1 
ATOM   4631  C  CD2 . TRP B 2 295 ? 138.684 111.283 164.982 1.00 73.51  ? 241 TRP E CD2 1 
ATOM   4632  N  NE1 . TRP B 2 295 ? 139.690 110.090 166.586 1.00 70.54  ? 241 TRP E NE1 1 
ATOM   4633  C  CE2 . TRP B 2 295 ? 138.872 109.987 165.494 1.00 74.26  ? 241 TRP E CE2 1 
ATOM   4634  C  CE3 . TRP B 2 295 ? 137.880 111.453 163.855 1.00 71.25  ? 241 TRP E CE3 1 
ATOM   4635  C  CZ2 . TRP B 2 295 ? 138.290 108.868 164.915 1.00 75.89  ? 241 TRP E CZ2 1 
ATOM   4636  C  CZ3 . TRP B 2 295 ? 137.300 110.341 163.283 1.00 71.96  ? 241 TRP E CZ3 1 
ATOM   4637  C  CH2 . TRP B 2 295 ? 137.509 109.065 163.812 1.00 77.20  ? 241 TRP E CH2 1 
ATOM   4638  N  N   . ILE B 2 296 ? 138.363 116.821 166.948 1.00 63.97  ? 242 ILE E N   1 
ATOM   4639  C  CA  . ILE B 2 296 ? 138.828 118.127 167.396 1.00 62.92  ? 242 ILE E CA  1 
ATOM   4640  C  C   . ILE B 2 296 ? 137.974 118.541 168.585 1.00 70.07  ? 242 ILE E C   1 
ATOM   4641  O  O   . ILE B 2 296 ? 136.749 118.386 168.555 1.00 68.44  ? 242 ILE E O   1 
ATOM   4642  C  CB  . ILE B 2 296 ? 138.753 119.172 166.267 1.00 58.12  ? 242 ILE E CB  1 
ATOM   4643  C  CG1 . ILE B 2 296 ? 139.764 118.847 165.171 1.00 53.46  ? 242 ILE E CG1 1 
ATOM   4644  C  CG2 . ILE B 2 296 ? 138.988 120.563 166.802 1.00 62.44  ? 242 ILE E CG2 1 
ATOM   4645  C  CD1 . ILE B 2 296 ? 139.727 119.804 164.017 1.00 47.15  ? 242 ILE E CD1 1 
ATOM   4646  N  N   . ASN B 2 297 ? 138.621 119.044 169.633 1.00 74.02  ? 243 ASN E N   1 
ATOM   4647  C  CA  . ASN B 2 297 ? 137.899 119.461 170.824 1.00 81.60  ? 243 ASN E CA  1 
ATOM   4648  C  C   . ASN B 2 297 ? 136.924 120.581 170.489 1.00 86.78  ? 243 ASN E C   1 
ATOM   4649  O  O   . ASN B 2 297 ? 137.224 121.464 169.683 1.00 90.17  ? 243 ASN E O   1 
ATOM   4650  C  CB  . ASN B 2 297 ? 138.881 119.918 171.900 1.00 83.61  ? 243 ASN E CB  1 
ATOM   4651  C  CG  . ASN B 2 297 ? 138.605 119.286 173.246 1.00 93.77  ? 243 ASN E CG  1 
ATOM   4652  O  OD1 . ASN B 2 297 ? 137.455 119.033 173.601 1.00 98.22  ? 243 ASN E OD1 1 
ATOM   4653  N  ND2 . ASN B 2 297 ? 139.660 119.024 174.003 1.00 88.72  ? 243 ASN E ND2 1 
ATOM   4654  N  N   . TYR B 2 298 ? 135.743 120.543 171.113 1.00 90.56  ? 244 TYR E N   1 
ATOM   4655  C  CA  . TYR B 2 298 ? 134.701 121.510 170.789 1.00 94.02  ? 244 TYR E CA  1 
ATOM   4656  C  C   . TYR B 2 298 ? 135.068 122.937 171.171 1.00 93.14  ? 244 TYR E C   1 
ATOM   4657  O  O   . TYR B 2 298 ? 134.447 123.873 170.656 1.00 91.16  ? 244 TYR E O   1 
ATOM   4658  C  CB  . TYR B 2 298 ? 133.375 121.126 171.454 1.00 90.17  ? 244 TYR E CB  1 
ATOM   4659  C  CG  . TYR B 2 298 ? 133.502 120.136 172.582 1.00 92.73  ? 244 TYR E CG  1 
ATOM   4660  C  CD1 . TYR B 2 298 ? 134.061 120.505 173.796 1.00 95.98  ? 244 TYR E CD1 1 
ATOM   4661  C  CD2 . TYR B 2 298 ? 133.051 118.835 172.438 1.00 88.36  ? 244 TYR E CD2 1 
ATOM   4662  C  CE1 . TYR B 2 298 ? 134.179 119.606 174.830 1.00 99.19  ? 244 TYR E CE1 1 
ATOM   4663  C  CE2 . TYR B 2 298 ? 133.164 117.927 173.467 1.00 97.74  ? 244 TYR E CE2 1 
ATOM   4664  C  CZ  . TYR B 2 298 ? 133.729 118.317 174.662 1.00 101.93 ? 244 TYR E CZ  1 
ATOM   4665  O  OH  . TYR B 2 298 ? 133.844 117.414 175.695 1.00 99.55  ? 244 TYR E OH  1 
ATOM   4666  N  N   . ASP B 2 299 ? 136.050 123.135 172.050 1.00 89.09  ? 245 ASP E N   1 
ATOM   4667  C  CA  . ASP B 2 299 ? 136.488 124.491 172.353 1.00 91.31  ? 245 ASP E CA  1 
ATOM   4668  C  C   . ASP B 2 299 ? 137.194 125.148 171.174 1.00 90.57  ? 245 ASP E C   1 
ATOM   4669  O  O   . ASP B 2 299 ? 137.246 126.380 171.109 1.00 89.84  ? 245 ASP E O   1 
ATOM   4670  C  CB  . ASP B 2 299 ? 137.399 124.485 173.580 1.00 98.80  ? 245 ASP E CB  1 
ATOM   4671  C  CG  . ASP B 2 299 ? 136.685 124.006 174.833 1.00 111.09 ? 245 ASP E CG  1 
ATOM   4672  O  OD1 . ASP B 2 299 ? 136.390 122.797 174.931 1.00 107.41 ? 245 ASP E OD1 1 
ATOM   4673  O  OD2 . ASP B 2 299 ? 136.414 124.841 175.720 1.00 117.47 ? 245 ASP E OD2 1 
ATOM   4674  N  N   . ALA B 2 300 ? 137.738 124.361 170.246 1.00 89.83  ? 246 ALA E N   1 
ATOM   4675  C  CA  . ALA B 2 300 ? 138.400 124.900 169.057 1.00 79.95  ? 246 ALA E CA  1 
ATOM   4676  C  C   . ALA B 2 300 ? 137.371 125.078 167.940 1.00 71.48  ? 246 ALA E C   1 
ATOM   4677  O  O   . ALA B 2 300 ? 137.374 124.391 166.919 1.00 64.52  ? 246 ALA E O   1 
ATOM   4678  C  CB  . ALA B 2 300 ? 139.545 123.994 168.630 1.00 71.04  ? 246 ALA E CB  1 
ATOM   4679  N  N   . SER B 2 301 ? 136.477 126.043 168.158 1.00 69.97  ? 247 SER E N   1 
ATOM   4680  C  CA  . SER B 2 301 ? 135.360 126.233 167.243 1.00 62.48  ? 247 SER E CA  1 
ATOM   4681  C  C   . SER B 2 301 ? 135.818 126.725 165.879 1.00 58.85  ? 247 SER E C   1 
ATOM   4682  O  O   . SER B 2 301 ? 135.194 126.396 164.866 1.00 60.07  ? 247 SER E O   1 
ATOM   4683  C  CB  . SER B 2 301 ? 134.350 127.208 167.841 1.00 62.27  ? 247 SER E CB  1 
ATOM   4684  O  OG  . SER B 2 301 ? 134.930 128.483 168.031 1.00 70.38  ? 247 SER E OG  1 
ATOM   4685  N  N   . ALA B 2 302 ? 136.885 127.522 165.832 1.00 55.93  ? 248 ALA E N   1 
ATOM   4686  C  CA  . ALA B 2 302 ? 137.330 128.084 164.563 1.00 51.21  ? 248 ALA E CA  1 
ATOM   4687  C  C   . ALA B 2 302 ? 137.716 126.987 163.580 1.00 51.83  ? 248 ALA E C   1 
ATOM   4688  O  O   . ALA B 2 302 ? 137.307 127.007 162.413 1.00 50.82  ? 248 ALA E O   1 
ATOM   4689  C  CB  . ALA B 2 302 ? 138.502 129.032 164.801 1.00 47.17  ? 248 ALA E CB  1 
ATOM   4690  N  N   . ALA B 2 303 ? 138.494 126.009 164.043 1.00 49.98  ? 249 ALA E N   1 
ATOM   4691  C  CA  . ALA B 2 303 ? 138.939 124.940 163.159 1.00 52.40  ? 249 ALA E CA  1 
ATOM   4692  C  C   . ALA B 2 303 ? 137.764 124.116 162.649 1.00 55.56  ? 249 ALA E C   1 
ATOM   4693  O  O   . ALA B 2 303 ? 137.704 123.779 161.463 1.00 55.12  ? 249 ALA E O   1 
ATOM   4694  C  CB  . ALA B 2 303 ? 139.947 124.051 163.882 1.00 52.00  ? 249 ALA E CB  1 
ATOM   4695  N  N   . ARG B 2 304 ? 136.819 123.786 163.528 1.00 54.44  ? 250 ARG E N   1 
ATOM   4696  C  CA  . ARG B 2 304 ? 135.686 122.964 163.119 1.00 47.10  ? 250 ARG E CA  1 
ATOM   4697  C  C   . ARG B 2 304 ? 134.785 123.701 162.137 1.00 46.12  ? 250 ARG E C   1 
ATOM   4698  O  O   . ARG B 2 304 ? 134.331 123.119 161.142 1.00 50.51  ? 250 ARG E O   1 
ATOM   4699  C  CB  . ARG B 2 304 ? 134.897 122.530 164.347 1.00 49.18  ? 250 ARG E CB  1 
ATOM   4700  C  CG  . ARG B 2 304 ? 135.648 121.602 165.266 1.00 54.50  ? 250 ARG E CG  1 
ATOM   4701  C  CD  . ARG B 2 304 ? 134.935 120.278 165.350 1.00 59.95  ? 250 ARG E CD  1 
ATOM   4702  N  NE  . ARG B 2 304 ? 134.528 119.954 166.710 1.00 64.15  ? 250 ARG E NE  1 
ATOM   4703  C  CZ  . ARG B 2 304 ? 133.633 119.028 167.022 1.00 64.85  ? 250 ARG E CZ  1 
ATOM   4704  N  NH1 . ARG B 2 304 ? 133.012 118.327 166.090 1.00 56.25  ? 250 ARG E NH1 1 
ATOM   4705  N  NH2 . ARG B 2 304 ? 133.352 118.803 168.300 1.00 76.67  ? 250 ARG E NH2 1 
ATOM   4706  N  N   . VAL B 2 305 ? 134.506 124.978 162.402 1.00 46.33  ? 251 VAL E N   1 
ATOM   4707  C  CA  . VAL B 2 305 ? 133.683 125.756 161.484 1.00 44.79  ? 251 VAL E CA  1 
ATOM   4708  C  C   . VAL B 2 305 ? 134.362 125.866 160.127 1.00 45.77  ? 251 VAL E C   1 
ATOM   4709  O  O   . VAL B 2 305 ? 133.719 125.710 159.079 1.00 46.84  ? 251 VAL E O   1 
ATOM   4710  C  CB  . VAL B 2 305 ? 133.372 127.142 162.078 1.00 39.95  ? 251 VAL E CB  1 
ATOM   4711  C  CG1 . VAL B 2 305 ? 132.638 127.990 161.072 1.00 35.94  ? 251 VAL E CG1 1 
ATOM   4712  C  CG2 . VAL B 2 305 ? 132.534 126.999 163.322 1.00 45.58  ? 251 VAL E CG2 1 
ATOM   4713  N  N   . ALA B 2 306 ? 135.673 126.129 160.121 1.00 43.62  ? 252 ALA E N   1 
ATOM   4714  C  CA  . ALA B 2 306 ? 136.393 126.213 158.858 1.00 40.96  ? 252 ALA E CA  1 
ATOM   4715  C  C   . ALA B 2 306 ? 136.367 124.887 158.116 1.00 44.14  ? 252 ALA E C   1 
ATOM   4716  O  O   . ALA B 2 306 ? 136.187 124.860 156.897 1.00 45.63  ? 252 ALA E O   1 
ATOM   4717  C  CB  . ALA B 2 306 ? 137.828 126.659 159.100 1.00 36.67  ? 252 ALA E CB  1 
ATOM   4718  N  N   . LEU B 2 307 ? 136.533 123.775 158.833 1.00 43.58  ? 253 LEU E N   1 
ATOM   4719  C  CA  . LEU B 2 307 ? 136.470 122.464 158.196 1.00 43.14  ? 253 LEU E CA  1 
ATOM   4720  C  C   . LEU B 2 307 ? 135.128 122.252 157.517 1.00 45.38  ? 253 LEU E C   1 
ATOM   4721  O  O   . LEU B 2 307 ? 135.068 121.892 156.337 1.00 47.83  ? 253 LEU E O   1 
ATOM   4722  C  CB  . LEU B 2 307 ? 136.711 121.364 159.225 1.00 43.67  ? 253 LEU E CB  1 
ATOM   4723  C  CG  . LEU B 2 307 ? 138.127 120.858 159.469 1.00 44.53  ? 253 LEU E CG  1 
ATOM   4724  C  CD1 . LEU B 2 307 ? 138.111 119.911 160.641 1.00 46.64  ? 253 LEU E CD1 1 
ATOM   4725  C  CD2 . LEU B 2 307 ? 138.666 120.163 158.243 1.00 40.89  ? 253 LEU E CD2 1 
ATOM   4726  N  N   . GLY B 2 308 ? 134.037 122.467 158.253 1.00 46.46  ? 254 GLY E N   1 
ATOM   4727  C  CA  . GLY B 2 308 ? 132.722 122.223 157.683 1.00 43.95  ? 254 GLY E CA  1 
ATOM   4728  C  C   . GLY B 2 308 ? 132.437 123.100 156.480 1.00 49.07  ? 254 GLY E C   1 
ATOM   4729  O  O   . GLY B 2 308 ? 132.015 122.618 155.422 1.00 52.40  ? 254 GLY E O   1 
ATOM   4730  N  N   . ILE B 2 309 ? 132.688 124.403 156.617 1.00 47.39  ? 255 ILE E N   1 
ATOM   4731  C  CA  . ILE B 2 309 ? 132.383 125.327 155.533 1.00 45.85  ? 255 ILE E CA  1 
ATOM   4732  C  C   . ILE B 2 309 ? 133.255 125.046 154.316 1.00 48.10  ? 255 ILE E C   1 
ATOM   4733  O  O   . ILE B 2 309 ? 132.763 125.014 153.182 1.00 48.83  ? 255 ILE E O   1 
ATOM   4734  C  CB  . ILE B 2 309 ? 132.526 126.775 156.025 1.00 43.65  ? 255 ILE E CB  1 
ATOM   4735  C  CG1 . ILE B 2 309 ? 131.404 127.080 157.013 1.00 43.00  ? 255 ILE E CG1 1 
ATOM   4736  C  CG2 . ILE B 2 309 ? 132.492 127.740 154.863 1.00 50.78  ? 255 ILE E CG2 1 
ATOM   4737  C  CD1 . ILE B 2 309 ? 131.448 128.452 157.585 1.00 46.07  ? 255 ILE E CD1 1 
ATOM   4738  N  N   . THR B 2 310 ? 134.556 124.828 154.523 1.00 45.42  ? 256 THR E N   1 
ATOM   4739  C  CA  . THR B 2 310 ? 135.450 124.575 153.402 1.00 43.47  ? 256 THR E CA  1 
ATOM   4740  C  C   . THR B 2 310 ? 135.114 123.266 152.703 1.00 47.56  ? 256 THR E C   1 
ATOM   4741  O  O   . THR B 2 310 ? 135.150 123.197 151.472 1.00 52.14  ? 256 THR E O   1 
ATOM   4742  C  CB  . THR B 2 310 ? 136.898 124.568 153.878 1.00 40.55  ? 256 THR E CB  1 
ATOM   4743  O  OG1 . THR B 2 310 ? 137.196 125.815 154.511 1.00 44.54  ? 256 THR E OG1 1 
ATOM   4744  C  CG2 . THR B 2 310 ? 137.837 124.375 152.708 1.00 39.33  ? 256 THR E CG2 1 
ATOM   4745  N  N   . THR B 2 311 ? 134.791 122.214 153.458 1.00 44.20  ? 257 THR E N   1 
ATOM   4746  C  CA  . THR B 2 311 ? 134.453 120.949 152.819 1.00 44.19  ? 257 THR E CA  1 
ATOM   4747  C  C   . THR B 2 311 ? 133.168 121.059 152.009 1.00 47.79  ? 257 THR E C   1 
ATOM   4748  O  O   . THR B 2 311 ? 133.106 120.567 150.879 1.00 51.61  ? 257 THR E O   1 
ATOM   4749  C  CB  . THR B 2 311 ? 134.343 119.839 153.856 1.00 45.73  ? 257 THR E CB  1 
ATOM   4750  O  OG1 . THR B 2 311 ? 133.608 120.312 154.987 1.00 54.91  ? 257 THR E OG1 1 
ATOM   4751  C  CG2 . THR B 2 311 ? 135.718 119.400 154.304 1.00 43.64  ? 257 THR E CG2 1 
ATOM   4752  N  N   . VAL B 2 312 ? 132.133 121.704 152.556 1.00 46.21  ? 258 VAL E N   1 
ATOM   4753  C  CA  . VAL B 2 312 ? 130.895 121.860 151.793 1.00 47.67  ? 258 VAL E CA  1 
ATOM   4754  C  C   . VAL B 2 312 ? 131.139 122.693 150.538 1.00 53.92  ? 258 VAL E C   1 
ATOM   4755  O  O   . VAL B 2 312 ? 130.695 122.339 149.436 1.00 57.26  ? 258 VAL E O   1 
ATOM   4756  C  CB  . VAL B 2 312 ? 129.796 122.476 152.677 1.00 46.44  ? 258 VAL E CB  1 
ATOM   4757  C  CG1 . VAL B 2 312 ? 128.586 122.840 151.841 1.00 47.53  ? 258 VAL E CG1 1 
ATOM   4758  C  CG2 . VAL B 2 312 ? 129.405 121.513 153.777 1.00 47.52  ? 258 VAL E CG2 1 
ATOM   4759  N  N   . LEU B 2 313 ? 131.861 123.805 150.684 1.00 53.23  ? 259 LEU E N   1 
ATOM   4760  C  CA  . LEU B 2 313 ? 132.132 124.675 149.548 1.00 49.61  ? 259 LEU E CA  1 
ATOM   4761  C  C   . LEU B 2 313 ? 132.937 123.954 148.474 1.00 55.25  ? 259 LEU E C   1 
ATOM   4762  O  O   . LEU B 2 313 ? 132.638 124.070 147.282 1.00 60.62  ? 259 LEU E O   1 
ATOM   4763  C  CB  . LEU B 2 313 ? 132.864 125.923 150.035 1.00 51.18  ? 259 LEU E CB  1 
ATOM   4764  C  CG  . LEU B 2 313 ? 133.297 126.979 149.027 1.00 64.30  ? 259 LEU E CG  1 
ATOM   4765  C  CD1 . LEU B 2 313 ? 132.090 127.629 148.382 1.00 70.58  ? 259 LEU E CD1 1 
ATOM   4766  C  CD2 . LEU B 2 313 ? 134.153 128.016 149.719 1.00 63.03  ? 259 LEU E CD2 1 
ATOM   4767  N  N   . THR B 2 314 ? 133.954 123.189 148.875 1.00 53.31  ? 260 THR E N   1 
ATOM   4768  C  CA  . THR B 2 314 ? 134.774 122.478 147.903 1.00 48.74  ? 260 THR E CA  1 
ATOM   4769  C  C   . THR B 2 314 ? 133.997 121.352 147.241 1.00 56.69  ? 260 THR E C   1 
ATOM   4770  O  O   . THR B 2 314 ? 134.203 121.062 146.058 1.00 63.66  ? 260 THR E O   1 
ATOM   4771  C  CB  . THR B 2 314 ? 136.028 121.931 148.575 1.00 44.30  ? 260 THR E CB  1 
ATOM   4772  O  OG1 . THR B 2 314 ? 136.610 122.949 149.392 1.00 48.77  ? 260 THR E OG1 1 
ATOM   4773  C  CG2 . THR B 2 314 ? 137.031 121.521 147.533 1.00 49.99  ? 260 THR E CG2 1 
ATOM   4774  N  N   . MET B 2 315 ? 133.113 120.691 147.986 1.00 56.66  ? 261 MET E N   1 
ATOM   4775  C  CA  . MET B 2 315 ? 132.273 119.669 147.380 1.00 57.28  ? 261 MET E CA  1 
ATOM   4776  C  C   . MET B 2 315 ? 131.395 120.272 146.296 1.00 63.53  ? 261 MET E C   1 
ATOM   4777  O  O   . MET B 2 315 ? 131.289 119.727 145.192 1.00 69.23  ? 261 MET E O   1 
ATOM   4778  C  CB  . MET B 2 315 ? 131.427 118.986 148.451 1.00 52.49  ? 261 MET E CB  1 
ATOM   4779  C  CG  . MET B 2 315 ? 130.595 117.843 147.938 1.00 55.41  ? 261 MET E CG  1 
ATOM   4780  S  SD  . MET B 2 315 ? 131.611 116.489 147.351 1.00 72.66  ? 261 MET E SD  1 
ATOM   4781  C  CE  . MET B 2 315 ? 132.624 116.207 148.792 1.00 47.77  ? 261 MET E CE  1 
ATOM   4782  N  N   . THR B 2 316 ? 130.778 121.422 146.580 1.00 61.39  ? 262 THR E N   1 
ATOM   4783  C  CA  . THR B 2 316 ? 129.986 122.086 145.548 1.00 64.89  ? 262 THR E CA  1 
ATOM   4784  C  C   . THR B 2 316 ? 130.859 122.524 144.379 1.00 70.52  ? 262 THR E C   1 
ATOM   4785  O  O   . THR B 2 316 ? 130.434 122.463 143.220 1.00 77.21  ? 262 THR E O   1 
ATOM   4786  C  CB  . THR B 2 316 ? 129.238 123.283 146.128 1.00 62.74  ? 262 THR E CB  1 
ATOM   4787  O  OG1 . THR B 2 316 ? 130.179 124.239 146.624 1.00 67.51  ? 262 THR E OG1 1 
ATOM   4788  C  CG2 . THR B 2 316 ? 128.315 122.840 147.250 1.00 60.77  ? 262 THR E CG2 1 
ATOM   4789  N  N   . THR B 2 317 ? 132.081 122.975 144.663 1.00 68.19  ? 263 THR E N   1 
ATOM   4790  C  CA  . THR B 2 317 ? 132.983 123.410 143.601 1.00 65.76  ? 263 THR E CA  1 
ATOM   4791  C  C   . THR B 2 317 ? 133.294 122.269 142.641 1.00 68.18  ? 263 THR E C   1 
ATOM   4792  O  O   . THR B 2 317 ? 133.148 122.411 141.419 1.00 78.85  ? 263 THR E O   1 
ATOM   4793  C  CB  . THR B 2 317 ? 134.270 123.968 144.209 1.00 63.90  ? 263 THR E CB  1 
ATOM   4794  O  OG1 . THR B 2 317 ? 133.987 125.196 144.890 1.00 65.94  ? 263 THR E OG1 1 
ATOM   4795  C  CG2 . THR B 2 317 ? 135.311 124.214 143.133 1.00 57.57  ? 263 THR E CG2 1 
ATOM   4796  N  N   . ILE B 2 318 ? 133.716 121.122 143.177 1.00 65.51  ? 264 ILE E N   1 
ATOM   4797  C  CA  . ILE B 2 318 ? 134.038 119.998 142.306 1.00 68.58  ? 264 ILE E CA  1 
ATOM   4798  C  C   . ILE B 2 318 ? 132.783 119.482 141.615 1.00 78.48  ? 264 ILE E C   1 
ATOM   4799  O  O   . ILE B 2 318 ? 132.841 119.052 140.457 1.00 85.77  ? 264 ILE E O   1 
ATOM   4800  C  CB  . ILE B 2 318 ? 134.773 118.879 143.072 1.00 62.19  ? 264 ILE E CB  1 
ATOM   4801  C  CG1 . ILE B 2 318 ? 133.835 118.114 143.999 1.00 65.71  ? 264 ILE E CG1 1 
ATOM   4802  C  CG2 . ILE B 2 318 ? 135.941 119.442 143.855 1.00 64.33  ? 264 ILE E CG2 1 
ATOM   4803  C  CD1 . ILE B 2 318 ? 133.596 116.696 143.561 1.00 63.95  ? 264 ILE E CD1 1 
ATOM   4804  N  N   . ASN B 2 319 ? 131.631 119.530 142.289 1.00 77.69  ? 265 ASN E N   1 
ATOM   4805  C  CA  . ASN B 2 319 ? 130.397 119.065 141.668 1.00 82.40  ? 265 ASN E CA  1 
ATOM   4806  C  C   . ASN B 2 319 ? 130.034 119.918 140.459 1.00 88.51  ? 265 ASN E C   1 
ATOM   4807  O  O   . ASN B 2 319 ? 129.683 119.390 139.400 1.00 90.94  ? 265 ASN E O   1 
ATOM   4808  C  CB  . ASN B 2 319 ? 129.268 119.065 142.696 1.00 83.22  ? 265 ASN E CB  1 
ATOM   4809  C  CG  . ASN B 2 319 ? 128.011 118.407 142.178 1.00 93.38  ? 265 ASN E CG  1 
ATOM   4810  O  OD1 . ASN B 2 319 ? 128.046 117.647 141.213 1.00 98.20  ? 265 ASN E OD1 1 
ATOM   4811  N  ND2 . ASN B 2 319 ? 126.889 118.692 142.822 1.00 101.97 ? 265 ASN E ND2 1 
ATOM   4812  N  N   . THR B 2 320 ? 130.118 121.243 140.595 1.00 88.45  ? 266 THR E N   1 
ATOM   4813  C  CA  . THR B 2 320 ? 129.813 122.109 139.459 1.00 92.69  ? 266 THR E CA  1 
ATOM   4814  C  C   . THR B 2 320 ? 130.832 121.934 138.342 1.00 93.53  ? 266 THR E C   1 
ATOM   4815  O  O   . THR B 2 320 ? 130.463 121.870 137.160 1.00 98.65  ? 266 THR E O   1 
ATOM   4816  C  CB  . THR B 2 320 ? 129.753 123.572 139.893 1.00 92.54  ? 266 THR E CB  1 
ATOM   4817  O  OG1 . THR B 2 320 ? 130.998 123.948 140.493 1.00 95.21  ? 266 THR E OG1 1 
ATOM   4818  C  CG2 . THR B 2 320 ? 128.616 123.794 140.884 1.00 85.09  ? 266 THR E CG2 1 
ATOM   4819  N  N   . HIS B 2 321 ? 132.118 121.849 138.694 1.00 89.63  ? 267 HIS E N   1 
ATOM   4820  C  CA  . HIS B 2 321 ? 133.141 121.689 137.668 1.00 92.36  ? 267 HIS E CA  1 
ATOM   4821  C  C   . HIS B 2 321 ? 132.940 120.402 136.883 1.00 97.10  ? 267 HIS E C   1 
ATOM   4822  O  O   . HIS B 2 321 ? 133.123 120.378 135.662 1.00 103.25 ? 267 HIS E O   1 
ATOM   4823  C  CB  . HIS B 2 321 ? 134.532 121.718 138.292 1.00 91.64  ? 267 HIS E CB  1 
ATOM   4824  C  CG  . HIS B 2 321 ? 135.608 121.234 137.374 1.00 103.21 ? 267 HIS E CG  1 
ATOM   4825  N  ND1 . HIS B 2 321 ? 135.777 121.730 136.099 1.00 109.64 ? 267 HIS E ND1 1 
ATOM   4826  C  CD2 . HIS B 2 321 ? 136.561 120.288 137.538 1.00 105.28 ? 267 HIS E CD2 1 
ATOM   4827  C  CE1 . HIS B 2 321 ? 136.794 121.116 135.522 1.00 106.75 ? 267 HIS E CE1 1 
ATOM   4828  N  NE2 . HIS B 2 321 ? 137.287 120.236 136.373 1.00 108.68 ? 267 HIS E NE2 1 
ATOM   4829  N  N   . LEU B 2 322 ? 132.570 119.316 137.563 1.00 95.14  ? 268 LEU E N   1 
ATOM   4830  C  CA  . LEU B 2 322 ? 132.290 118.081 136.841 1.00 98.93  ? 268 LEU E CA  1 
ATOM   4831  C  C   . LEU B 2 322 ? 131.010 118.191 136.022 1.00 100.73 ? 268 LEU E C   1 
ATOM   4832  O  O   . LEU B 2 322 ? 130.988 117.815 134.845 1.00 101.39 ? 268 LEU E O   1 
ATOM   4833  C  CB  . LEU B 2 322 ? 132.192 116.906 137.807 1.00 96.66  ? 268 LEU E CB  1 
ATOM   4834  C  CG  . LEU B 2 322 ? 131.747 115.635 137.084 1.00 95.26  ? 268 LEU E CG  1 
ATOM   4835  C  CD1 . LEU B 2 322 ? 132.935 114.920 136.456 1.00 92.34  ? 268 LEU E CD1 1 
ATOM   4836  C  CD2 . LEU B 2 322 ? 130.973 114.719 138.001 1.00 89.81  ? 268 LEU E CD2 1 
ATOM   4837  N  N   . ARG B 2 323 ? 129.935 118.711 136.620 1.00 99.86  ? 269 ARG E N   1 
ATOM   4838  C  CA  . ARG B 2 323 ? 128.641 118.725 135.949 1.00 106.74 ? 269 ARG E CA  1 
ATOM   4839  C  C   . ARG B 2 323 ? 128.628 119.631 134.729 1.00 108.18 ? 269 ARG E C   1 
ATOM   4840  O  O   . ARG B 2 323 ? 127.769 119.461 133.859 1.00 106.56 ? 269 ARG E O   1 
ATOM   4841  C  CB  . ARG B 2 323 ? 127.546 119.152 136.925 1.00 105.54 ? 269 ARG E CB  1 
ATOM   4842  C  CG  . ARG B 2 323 ? 126.196 118.513 136.655 1.00 108.91 ? 269 ARG E CG  1 
ATOM   4843  C  CD  . ARG B 2 323 ? 125.209 118.841 137.759 1.00 115.74 ? 269 ARG E CD  1 
ATOM   4844  N  NE  . ARG B 2 323 ? 124.094 117.904 137.799 1.00 121.36 ? 269 ARG E NE  1 
ATOM   4845  C  CZ  . ARG B 2 323 ? 123.138 117.917 138.718 1.00 121.23 ? 269 ARG E CZ  1 
ATOM   4846  N  NH1 . ARG B 2 323 ? 123.123 118.819 139.685 1.00 112.78 ? 269 ARG E NH1 1 
ATOM   4847  N  NH2 . ARG B 2 323 ? 122.175 117.001 138.667 1.00 121.65 ? 269 ARG E NH2 1 
ATOM   4848  N  N   . GLU B 2 324 ? 129.546 120.594 134.644 1.00 108.25 ? 270 GLU E N   1 
ATOM   4849  C  CA  . GLU B 2 324 ? 129.662 121.359 133.407 1.00 108.54 ? 270 GLU E CA  1 
ATOM   4850  C  C   . GLU B 2 324 ? 130.050 120.455 132.241 1.00 109.48 ? 270 GLU E C   1 
ATOM   4851  O  O   . GLU B 2 324 ? 129.516 120.592 131.135 1.00 109.12 ? 270 GLU E O   1 
ATOM   4852  C  CB  . GLU B 2 324 ? 130.670 122.494 133.574 1.00 107.79 ? 270 GLU E CB  1 
ATOM   4853  C  CG  . GLU B 2 324 ? 130.168 123.642 134.437 1.00 107.31 ? 270 GLU E CG  1 
ATOM   4854  C  CD  . GLU B 2 324 ? 131.117 124.822 134.441 1.00 108.65 ? 270 GLU E CD  1 
ATOM   4855  O  OE1 . GLU B 2 324 ? 132.144 124.758 133.735 1.00 111.57 ? 270 GLU E OE1 1 
ATOM   4856  O  OE2 . GLU B 2 324 ? 130.837 125.811 135.150 1.00 109.56 ? 270 GLU E OE2 1 
ATOM   4857  N  N   . THR B 2 325 ? 130.974 119.521 132.470 1.00 108.93 ? 271 THR E N   1 
ATOM   4858  C  CA  . THR B 2 325 ? 131.376 118.597 131.415 1.00 109.23 ? 271 THR E CA  1 
ATOM   4859  C  C   . THR B 2 325 ? 130.334 117.514 131.170 1.00 107.51 ? 271 THR E C   1 
ATOM   4860  O  O   . THR B 2 325 ? 130.250 116.981 130.058 1.00 101.02 ? 271 THR E O   1 
ATOM   4861  C  CB  . THR B 2 325 ? 132.718 117.951 131.758 1.00 105.77 ? 271 THR E CB  1 
ATOM   4862  O  OG1 . THR B 2 325 ? 132.539 117.016 132.829 1.00 102.17 ? 271 THR E OG1 1 
ATOM   4863  C  CG2 . THR B 2 325 ? 133.724 119.012 132.185 1.00 102.77 ? 271 THR E CG2 1 
ATOM   4864  N  N   . LEU B 2 326 ? 129.548 117.172 132.183 1.00 108.04 ? 272 LEU E N   1 
ATOM   4865  C  CA  . LEU B 2 326 ? 128.550 116.127 132.027 1.00 106.00 ? 272 LEU E CA  1 
ATOM   4866  C  C   . LEU B 2 326 ? 127.459 116.570 131.054 1.00 103.52 ? 272 LEU E C   1 
ATOM   4867  O  O   . LEU B 2 326 ? 127.060 117.739 131.053 1.00 102.19 ? 272 LEU E O   1 
ATOM   4868  C  CB  . LEU B 2 326 ? 127.930 115.776 133.376 1.00 108.02 ? 272 LEU E CB  1 
ATOM   4869  C  CG  . LEU B 2 326 ? 128.879 115.315 134.480 1.00 104.97 ? 272 LEU E CG  1 
ATOM   4870  C  CD1 . LEU B 2 326 ? 128.100 115.055 135.759 1.00 100.00 ? 272 LEU E CD1 1 
ATOM   4871  C  CD2 . LEU B 2 326 ? 129.644 114.077 134.051 1.00 99.66  ? 272 LEU E CD2 1 
ATOM   4872  N  N   . PRO B 2 327 ? 126.963 115.667 130.217 1.00 101.30 ? 273 PRO E N   1 
ATOM   4873  C  CA  . PRO B 2 327 ? 125.877 116.027 129.302 1.00 98.70  ? 273 PRO E CA  1 
ATOM   4874  C  C   . PRO B 2 327 ? 124.576 116.287 130.044 1.00 101.80 ? 273 PRO E C   1 
ATOM   4875  O  O   . PRO B 2 327 ? 124.311 115.718 131.105 1.00 100.82 ? 273 PRO E O   1 
ATOM   4876  C  CB  . PRO B 2 327 ? 125.759 114.798 128.398 1.00 92.00  ? 273 PRO E CB  1 
ATOM   4877  C  CG  . PRO B 2 327 ? 126.261 113.674 129.250 1.00 94.61  ? 273 PRO E CG  1 
ATOM   4878  C  CD  . PRO B 2 327 ? 127.361 114.256 130.083 1.00 93.75  ? 273 PRO E CD  1 
ATOM   4879  N  N   . LYS B 2 328 ? 123.749 117.152 129.457 1.00 103.45 ? 274 LYS E N   1 
ATOM   4880  C  CA  . LYS B 2 328 ? 122.459 117.516 130.043 1.00 105.03 ? 274 LYS E CA  1 
ATOM   4881  C  C   . LYS B 2 328 ? 121.400 116.468 129.689 1.00 99.03  ? 274 LYS E C   1 
ATOM   4882  O  O   . LYS B 2 328 ? 120.397 116.737 129.030 1.00 93.06  ? 274 LYS E O   1 
ATOM   4883  C  CB  . LYS B 2 328 ? 122.042 118.905 129.578 1.00 106.64 ? 274 LYS E CB  1 
ATOM   4884  C  CG  . LYS B 2 328 ? 122.976 120.031 130.001 1.00 105.75 ? 274 LYS E CG  1 
ATOM   4885  C  CD  . LYS B 2 328 ? 122.485 121.367 129.448 1.00 117.71 ? 274 LYS E CD  1 
ATOM   4886  C  CE  . LYS B 2 328 ? 123.248 122.545 130.038 1.00 125.01 ? 274 LYS E CE  1 
ATOM   4887  N  NZ  . LYS B 2 328 ? 122.757 123.851 129.510 1.00 127.42 ? 274 LYS E NZ  1 
ATOM   4888  N  N   . ILE B 2 329 ? 121.648 115.248 130.151 1.00 96.44  ? 275 ILE E N   1 
ATOM   4889  C  CA  . ILE B 2 329 ? 120.806 114.104 129.820 1.00 93.60  ? 275 ILE E CA  1 
ATOM   4890  C  C   . ILE B 2 329 ? 119.598 114.078 130.747 1.00 88.63  ? 275 ILE E C   1 
ATOM   4891  O  O   . ILE B 2 329 ? 119.628 114.695 131.819 1.00 91.73  ? 275 ILE E O   1 
ATOM   4892  C  CB  . ILE B 2 329 ? 121.603 112.794 129.901 1.00 97.79  ? 275 ILE E CB  1 
ATOM   4893  C  CG1 . ILE B 2 329 ? 122.113 112.573 131.322 1.00 95.92  ? 275 ILE E CG1 1 
ATOM   4894  C  CG2 . ILE B 2 329 ? 122.751 112.818 128.908 1.00 93.59  ? 275 ILE E CG2 1 
ATOM   4895  C  CD1 . ILE B 2 329 ? 122.782 111.244 131.518 1.00 88.12  ? 275 ILE E CD1 1 
ATOM   4896  N  N   . PRO B 2 330 ? 118.519 113.401 130.373 1.00 87.13  ? 276 PRO E N   1 
ATOM   4897  C  CA  . PRO B 2 330 ? 117.323 113.388 131.220 1.00 89.38  ? 276 PRO E CA  1 
ATOM   4898  C  C   . PRO B 2 330 ? 117.324 112.281 132.258 1.00 96.78  ? 276 PRO E C   1 
ATOM   4899  O  O   . PRO B 2 330 ? 116.258 111.904 132.750 1.00 99.40  ? 276 PRO E O   1 
ATOM   4900  C  CB  . PRO B 2 330 ? 116.201 113.178 130.205 1.00 93.41  ? 276 PRO E CB  1 
ATOM   4901  C  CG  . PRO B 2 330 ? 116.837 112.272 129.213 1.00 99.01  ? 276 PRO E CG  1 
ATOM   4902  C  CD  . PRO B 2 330 ? 118.267 112.739 129.083 1.00 93.13  ? 276 PRO E CD  1 
ATOM   4903  N  N   . TYR B 2 331 ? 118.485 111.712 132.569 1.00 97.99  ? 277 TYR E N   1 
ATOM   4904  C  CA  . TYR B 2 331 ? 118.560 110.664 133.577 1.00 93.11  ? 277 TYR E CA  1 
ATOM   4905  C  C   . TYR B 2 331 ? 119.805 110.865 134.426 1.00 91.64  ? 277 TYR E C   1 
ATOM   4906  O  O   . TYR B 2 331 ? 120.708 111.624 134.073 1.00 95.67  ? 277 TYR E O   1 
ATOM   4907  C  CB  . TYR B 2 331 ? 118.539 109.261 132.949 1.00 91.04  ? 277 TYR E CB  1 
ATOM   4908  C  CG  . TYR B 2 331 ? 119.519 109.040 131.819 1.00 93.82  ? 277 TYR E CG  1 
ATOM   4909  C  CD1 . TYR B 2 331 ? 119.269 109.537 130.548 1.00 94.24  ? 277 TYR E CD1 1 
ATOM   4910  C  CD2 . TYR B 2 331 ? 120.675 108.306 132.015 1.00 88.35  ? 277 TYR E CD2 1 
ATOM   4911  C  CE1 . TYR B 2 331 ? 120.154 109.330 129.515 1.00 91.27  ? 277 TYR E CE1 1 
ATOM   4912  C  CE2 . TYR B 2 331 ? 121.560 108.089 130.987 1.00 86.58  ? 277 TYR E CE2 1 
ATOM   4913  C  CZ  . TYR B 2 331 ? 121.296 108.604 129.740 1.00 87.71  ? 277 TYR E CZ  1 
ATOM   4914  O  OH  . TYR B 2 331 ? 122.180 108.391 128.711 1.00 85.68  ? 277 TYR E OH  1 
ATOM   4915  N  N   . VAL B 2 332 ? 119.830 110.183 135.566 1.00 89.67  ? 278 VAL E N   1 
ATOM   4916  C  CA  . VAL B 2 332 ? 120.886 110.349 136.557 1.00 90.74  ? 278 VAL E CA  1 
ATOM   4917  C  C   . VAL B 2 332 ? 121.930 109.254 136.372 1.00 88.84  ? 278 VAL E C   1 
ATOM   4918  O  O   . VAL B 2 332 ? 121.601 108.062 136.346 1.00 88.30  ? 278 VAL E O   1 
ATOM   4919  C  CB  . VAL B 2 332 ? 120.304 110.324 137.979 1.00 93.63  ? 278 VAL E CB  1 
ATOM   4920  C  CG1 . VAL B 2 332 ? 119.293 109.194 138.119 1.00 90.06  ? 278 VAL E CG1 1 
ATOM   4921  C  CG2 . VAL B 2 332 ? 121.411 110.177 139.003 1.00 89.92  ? 278 VAL E CG2 1 
ATOM   4922  N  N   . LYS B 2 333 ? 123.189 109.658 136.247 1.00 84.98  ? 279 LYS E N   1 
ATOM   4923  C  CA  . LYS B 2 333 ? 124.285 108.725 136.043 1.00 83.47  ? 279 LYS E CA  1 
ATOM   4924  C  C   . LYS B 2 333 ? 124.826 108.228 137.381 1.00 88.83  ? 279 LYS E C   1 
ATOM   4925  O  O   . LYS B 2 333 ? 124.462 108.714 138.453 1.00 88.31  ? 279 LYS E O   1 
ATOM   4926  C  CB  . LYS B 2 333 ? 125.410 109.378 135.243 1.00 76.67  ? 279 LYS E CB  1 
ATOM   4927  C  CG  . LYS B 2 333 ? 124.971 110.436 134.257 1.00 79.75  ? 279 LYS E CG  1 
ATOM   4928  C  CD  . LYS B 2 333 ? 126.175 111.214 133.768 1.00 86.45  ? 279 LYS E CD  1 
ATOM   4929  C  CE  . LYS B 2 333 ? 125.775 112.475 133.028 1.00 93.03  ? 279 LYS E CE  1 
ATOM   4930  N  NZ  . LYS B 2 333 ? 125.052 113.424 133.912 1.00 92.72  ? 279 LYS E NZ  1 
ATOM   4931  N  N   . ALA B 2 334 ? 125.718 107.238 137.301 1.00 84.22  ? 280 ALA E N   1 
ATOM   4932  C  CA  . ALA B 2 334 ? 126.340 106.694 138.504 1.00 79.85  ? 280 ALA E CA  1 
ATOM   4933  C  C   . ALA B 2 334 ? 127.173 107.747 139.219 1.00 77.15  ? 280 ALA E C   1 
ATOM   4934  O  O   . ALA B 2 334 ? 127.118 107.870 140.451 1.00 85.35  ? 280 ALA E O   1 
ATOM   4935  C  CB  . ALA B 2 334 ? 127.204 105.490 138.137 1.00 71.62  ? 280 ALA E CB  1 
ATOM   4936  N  N   . ILE B 2 335 ? 127.945 108.522 138.459 1.00 67.52  ? 281 ILE E N   1 
ATOM   4937  C  CA  . ILE B 2 335 ? 128.807 109.533 139.053 1.00 70.39  ? 281 ILE E CA  1 
ATOM   4938  C  C   . ILE B 2 335 ? 127.975 110.582 139.782 1.00 81.59  ? 281 ILE E C   1 
ATOM   4939  O  O   . ILE B 2 335 ? 128.388 111.098 140.828 1.00 85.23  ? 281 ILE E O   1 
ATOM   4940  C  CB  . ILE B 2 335 ? 129.714 110.139 137.966 1.00 72.98  ? 281 ILE E CB  1 
ATOM   4941  C  CG1 . ILE B 2 335 ? 130.821 110.984 138.586 1.00 78.45  ? 281 ILE E CG1 1 
ATOM   4942  C  CG2 . ILE B 2 335 ? 128.910 110.947 136.963 1.00 78.32  ? 281 ILE E CG2 1 
ATOM   4943  C  CD1 . ILE B 2 335 ? 131.939 111.290 137.622 1.00 78.33  ? 281 ILE E CD1 1 
ATOM   4944  N  N   . ASP B 2 336 ? 126.782 110.889 139.267 1.00 81.20  ? 282 ASP E N   1 
ATOM   4945  C  CA  . ASP B 2 336 ? 125.880 111.795 139.970 1.00 78.75  ? 282 ASP E CA  1 
ATOM   4946  C  C   . ASP B 2 336 ? 125.442 111.217 141.309 1.00 78.85  ? 282 ASP E C   1 
ATOM   4947  O  O   . ASP B 2 336 ? 125.380 111.935 142.312 1.00 80.89  ? 282 ASP E O   1 
ATOM   4948  C  CB  . ASP B 2 336 ? 124.664 112.099 139.102 1.00 78.30  ? 282 ASP E CB  1 
ATOM   4949  C  CG  . ASP B 2 336 ? 125.041 112.691 137.771 1.00 88.00  ? 282 ASP E CG  1 
ATOM   4950  O  OD1 . ASP B 2 336 ? 126.232 113.009 137.586 1.00 90.85  ? 282 ASP E OD1 1 
ATOM   4951  O  OD2 . ASP B 2 336 ? 124.151 112.835 136.909 1.00 94.28  ? 282 ASP E OD2 1 
ATOM   4952  N  N   . MET B 2 337 ? 125.120 109.924 141.343 1.00 78.75  ? 283 MET E N   1 
ATOM   4953  C  CA  . MET B 2 337 ? 124.719 109.305 142.601 1.00 80.60  ? 283 MET E CA  1 
ATOM   4954  C  C   . MET B 2 337 ? 125.846 109.365 143.619 1.00 75.26  ? 283 MET E C   1 
ATOM   4955  O  O   . MET B 2 337 ? 125.622 109.694 144.791 1.00 80.06  ? 283 MET E O   1 
ATOM   4956  C  CB  . MET B 2 337 ? 124.290 107.858 142.364 1.00 83.75  ? 283 MET E CB  1 
ATOM   4957  C  CG  . MET B 2 337 ? 122.973 107.697 141.615 1.00 94.97  ? 283 MET E CG  1 
ATOM   4958  S  SD  . MET B 2 337 ? 121.511 107.875 142.660 1.00 132.99 ? 283 MET E SD  1 
ATOM   4959  C  CE  . MET B 2 337 ? 121.210 109.641 142.592 1.00 97.74  ? 283 MET E CE  1 
ATOM   4960  N  N   . TYR B 2 338 ? 127.069 109.069 143.183 1.00 71.05  ? 284 TYR E N   1 
ATOM   4961  C  CA  . TYR B 2 338 ? 128.196 109.112 144.103 1.00 67.44  ? 284 TYR E CA  1 
ATOM   4962  C  C   . TYR B 2 338 ? 128.423 110.521 144.633 1.00 70.77  ? 284 TYR E C   1 
ATOM   4963  O  O   . TYR B 2 338 ? 128.648 110.713 145.836 1.00 75.49  ? 284 TYR E O   1 
ATOM   4964  C  CB  . TYR B 2 338 ? 129.451 108.595 143.416 1.00 69.83  ? 284 TYR E CB  1 
ATOM   4965  C  CG  . TYR B 2 338 ? 130.519 108.170 144.382 1.00 68.92  ? 284 TYR E CG  1 
ATOM   4966  C  CD1 . TYR B 2 338 ? 130.414 106.972 145.065 1.00 71.69  ? 284 TYR E CD1 1 
ATOM   4967  C  CD2 . TYR B 2 338 ? 131.630 108.965 144.615 1.00 63.77  ? 284 TYR E CD2 1 
ATOM   4968  C  CE1 . TYR B 2 338 ? 131.377 106.575 145.947 1.00 72.49  ? 284 TYR E CE1 1 
ATOM   4969  C  CE2 . TYR B 2 338 ? 132.604 108.574 145.501 1.00 68.18  ? 284 TYR E CE2 1 
ATOM   4970  C  CZ  . TYR B 2 338 ? 132.471 107.375 146.164 1.00 74.71  ? 284 TYR E CZ  1 
ATOM   4971  O  OH  . TYR B 2 338 ? 133.429 106.963 147.054 1.00 80.50  ? 284 TYR E OH  1 
ATOM   4972  N  N   . LEU B 2 339 ? 128.361 111.523 143.752 1.00 67.70  ? 285 LEU E N   1 
ATOM   4973  C  CA  . LEU B 2 339 ? 128.591 112.896 144.186 1.00 66.76  ? 285 LEU E CA  1 
ATOM   4974  C  C   . LEU B 2 339 ? 127.505 113.371 145.144 1.00 69.33  ? 285 LEU E C   1 
ATOM   4975  O  O   . LEU B 2 339 ? 127.793 114.072 146.123 1.00 69.74  ? 285 LEU E O   1 
ATOM   4976  C  CB  . LEU B 2 339 ? 128.679 113.822 142.979 1.00 67.89  ? 285 LEU E CB  1 
ATOM   4977  C  CG  . LEU B 2 339 ? 129.912 113.673 142.093 1.00 72.02  ? 285 LEU E CG  1 
ATOM   4978  C  CD1 . LEU B 2 339 ? 130.196 114.990 141.412 1.00 77.61  ? 285 LEU E CD1 1 
ATOM   4979  C  CD2 . LEU B 2 339 ? 131.110 113.217 142.894 1.00 70.03  ? 285 LEU E CD2 1 
ATOM   4980  N  N   . MET B 2 340 ? 126.249 113.013 144.876 1.00 66.66  ? 286 MET E N   1 
ATOM   4981  C  CA  . MET B 2 340 ? 125.173 113.413 145.774 1.00 66.11  ? 286 MET E CA  1 
ATOM   4982  C  C   . MET B 2 340 ? 125.315 112.744 147.135 1.00 65.22  ? 286 MET E C   1 
ATOM   4983  O  O   . MET B 2 340 ? 125.079 113.377 148.170 1.00 65.15  ? 286 MET E O   1 
ATOM   4984  C  CB  . MET B 2 340 ? 123.818 113.100 145.145 1.00 68.29  ? 286 MET E CB  1 
ATOM   4985  C  CG  . MET B 2 340 ? 122.634 113.498 146.006 1.00 85.22  ? 286 MET E CG  1 
ATOM   4986  S  SD  . MET B 2 340 ? 122.757 115.158 146.706 1.00 109.53 ? 286 MET E SD  1 
ATOM   4987  C  CE  . MET B 2 340 ? 122.742 116.170 145.232 1.00 93.42  ? 286 MET E CE  1 
ATOM   4988  N  N   . GLY B 2 341 ? 125.714 111.471 147.160 1.00 62.15  ? 287 GLY E N   1 
ATOM   4989  C  CA  . GLY B 2 341 ? 125.972 110.823 148.435 1.00 56.68  ? 287 GLY E CA  1 
ATOM   4990  C  C   . GLY B 2 341 ? 127.080 111.499 149.221 1.00 60.36  ? 287 GLY E C   1 
ATOM   4991  O  O   . GLY B 2 341 ? 126.953 111.723 150.429 1.00 64.56  ? 287 GLY E O   1 
ATOM   4992  N  N   . CYS B 2 342 ? 128.179 111.838 148.547 1.00 60.49  ? 288 CYS E N   1 
ATOM   4993  C  CA  . CYS B 2 342 ? 129.278 112.511 149.231 1.00 55.30  ? 288 CYS E CA  1 
ATOM   4994  C  C   . CYS B 2 342 ? 128.847 113.870 149.773 1.00 53.75  ? 288 CYS E C   1 
ATOM   4995  O  O   . CYS B 2 342 ? 129.219 114.250 150.893 1.00 57.41  ? 288 CYS E O   1 
ATOM   4996  C  CB  . CYS B 2 342 ? 130.468 112.654 148.287 1.00 54.72  ? 288 CYS E CB  1 
ATOM   4997  S  SG  . CYS B 2 342 ? 131.279 111.090 147.893 1.00 69.90  ? 288 CYS E SG  1 
ATOM   4998  N  N   . PHE B 2 343 ? 128.061 114.616 148.994 1.00 51.00  ? 289 PHE E N   1 
ATOM   4999  C  CA  . PHE B 2 343 ? 127.557 115.896 149.480 1.00 49.28  ? 289 PHE E CA  1 
ATOM   5000  C  C   . PHE B 2 343 ? 126.672 115.711 150.701 1.00 53.60  ? 289 PHE E C   1 
ATOM   5001  O  O   . PHE B 2 343 ? 126.738 116.501 151.650 1.00 58.53  ? 289 PHE E O   1 
ATOM   5002  C  CB  . PHE B 2 343 ? 126.785 116.618 148.383 1.00 50.75  ? 289 PHE E CB  1 
ATOM   5003  C  CG  . PHE B 2 343 ? 126.273 117.963 148.800 1.00 53.24  ? 289 PHE E CG  1 
ATOM   5004  C  CD1 . PHE B 2 343 ? 125.041 118.093 149.412 1.00 55.83  ? 289 PHE E CD1 1 
ATOM   5005  C  CD2 . PHE B 2 343 ? 127.032 119.095 148.596 1.00 52.63  ? 289 PHE E CD2 1 
ATOM   5006  C  CE1 . PHE B 2 343 ? 124.578 119.324 149.805 1.00 57.41  ? 289 PHE E CE1 1 
ATOM   5007  C  CE2 . PHE B 2 343 ? 126.570 120.328 148.980 1.00 53.11  ? 289 PHE E CE2 1 
ATOM   5008  C  CZ  . PHE B 2 343 ? 125.343 120.444 149.588 1.00 58.74  ? 289 PHE E CZ  1 
ATOM   5009  N  N   . VAL B 2 344 ? 125.816 114.690 150.686 1.00 56.51  ? 290 VAL E N   1 
ATOM   5010  C  CA  . VAL B 2 344 ? 124.958 114.435 151.838 1.00 55.43  ? 290 VAL E CA  1 
ATOM   5011  C  C   . VAL B 2 344 ? 125.802 114.160 153.071 1.00 55.67  ? 290 VAL E C   1 
ATOM   5012  O  O   . VAL B 2 344 ? 125.526 114.680 154.159 1.00 57.71  ? 290 VAL E O   1 
ATOM   5013  C  CB  . VAL B 2 344 ? 123.989 113.276 151.538 1.00 55.91  ? 290 VAL E CB  1 
ATOM   5014  C  CG1 . VAL B 2 344 ? 123.456 112.681 152.824 1.00 50.94  ? 290 VAL E CG1 1 
ATOM   5015  C  CG2 . VAL B 2 344 ? 122.844 113.764 150.670 1.00 57.84  ? 290 VAL E CG2 1 
ATOM   5016  N  N   . PHE B 2 345 ? 126.862 113.367 152.917 1.00 52.70  ? 291 PHE E N   1 
ATOM   5017  C  CA  . PHE B 2 345 ? 127.728 113.072 154.056 1.00 51.88  ? 291 PHE E CA  1 
ATOM   5018  C  C   . PHE B 2 345 ? 128.381 114.334 154.614 1.00 52.45  ? 291 PHE E C   1 
ATOM   5019  O  O   . PHE B 2 345 ? 128.380 114.558 155.833 1.00 55.08  ? 291 PHE E O   1 
ATOM   5020  C  CB  . PHE B 2 345 ? 128.792 112.056 153.658 1.00 51.90  ? 291 PHE E CB  1 
ATOM   5021  C  CG  . PHE B 2 345 ? 128.341 110.639 153.773 1.00 55.92  ? 291 PHE E CG  1 
ATOM   5022  C  CD1 . PHE B 2 345 ? 128.272 110.024 155.006 1.00 61.93  ? 291 PHE E CD1 1 
ATOM   5023  C  CD2 . PHE B 2 345 ? 127.993 109.916 152.654 1.00 61.17  ? 291 PHE E CD2 1 
ATOM   5024  C  CE1 . PHE B 2 345 ? 127.860 108.721 155.117 1.00 64.17  ? 291 PHE E CE1 1 
ATOM   5025  C  CE2 . PHE B 2 345 ? 127.582 108.611 152.763 1.00 65.79  ? 291 PHE E CE2 1 
ATOM   5026  C  CZ  . PHE B 2 345 ? 127.517 108.013 153.996 1.00 63.13  ? 291 PHE E CZ  1 
ATOM   5027  N  N   . VAL B 2 346 ? 128.950 115.174 153.744 1.00 46.55  ? 292 VAL E N   1 
ATOM   5028  C  CA  . VAL B 2 346 ? 129.667 116.344 154.254 1.00 44.96  ? 292 VAL E CA  1 
ATOM   5029  C  C   . VAL B 2 346 ? 128.698 117.345 154.882 1.00 50.35  ? 292 VAL E C   1 
ATOM   5030  O  O   . VAL B 2 346 ? 129.007 117.977 155.905 1.00 54.47  ? 292 VAL E O   1 
ATOM   5031  C  CB  . VAL B 2 346 ? 130.538 116.990 153.158 1.00 44.03  ? 292 VAL E CB  1 
ATOM   5032  C  CG1 . VAL B 2 346 ? 131.487 115.973 152.573 1.00 48.12  ? 292 VAL E CG1 1 
ATOM   5033  C  CG2 . VAL B 2 346 ? 129.704 117.614 152.070 1.00 51.36  ? 292 VAL E CG2 1 
ATOM   5034  N  N   . PHE B 2 347 ? 127.506 117.496 154.302 1.00 49.95  ? 293 PHE E N   1 
ATOM   5035  C  CA  . PHE B 2 347 ? 126.526 118.395 154.897 1.00 53.36  ? 293 PHE E CA  1 
ATOM   5036  C  C   . PHE B 2 347 ? 126.049 117.871 156.245 1.00 55.71  ? 293 PHE E C   1 
ATOM   5037  O  O   . PHE B 2 347 ? 125.838 118.652 157.180 1.00 55.86  ? 293 PHE E O   1 
ATOM   5038  C  CB  . PHE B 2 347 ? 125.349 118.593 153.950 1.00 53.75  ? 293 PHE E CB  1 
ATOM   5039  C  CG  . PHE B 2 347 ? 124.367 119.615 154.422 1.00 61.88  ? 293 PHE E CG  1 
ATOM   5040  C  CD1 . PHE B 2 347 ? 124.640 120.961 154.297 1.00 64.07  ? 293 PHE E CD1 1 
ATOM   5041  C  CD2 . PHE B 2 347 ? 123.169 119.232 154.991 1.00 60.08  ? 293 PHE E CD2 1 
ATOM   5042  C  CE1 . PHE B 2 347 ? 123.738 121.905 154.731 1.00 62.10  ? 293 PHE E CE1 1 
ATOM   5043  C  CE2 . PHE B 2 347 ? 122.263 120.174 155.424 1.00 56.22  ? 293 PHE E CE2 1 
ATOM   5044  C  CZ  . PHE B 2 347 ? 122.548 121.510 155.294 1.00 59.03  ? 293 PHE E CZ  1 
ATOM   5045  N  N   . LEU B 2 348 ? 125.873 116.555 156.367 1.00 53.14  ? 294 LEU E N   1 
ATOM   5046  C  CA  . LEU B 2 348 ? 125.496 115.989 157.655 1.00 50.36  ? 294 LEU E CA  1 
ATOM   5047  C  C   . LEU B 2 348 ? 126.575 116.235 158.698 1.00 50.65  ? 294 LEU E C   1 
ATOM   5048  O  O   . LEU B 2 348 ? 126.267 116.507 159.861 1.00 55.28  ? 294 LEU E O   1 
ATOM   5049  C  CB  . LEU B 2 348 ? 125.215 114.497 157.518 1.00 52.14  ? 294 LEU E CB  1 
ATOM   5050  C  CG  . LEU B 2 348 ? 123.863 114.102 156.932 1.00 51.29  ? 294 LEU E CG  1 
ATOM   5051  C  CD1 . LEU B 2 348 ? 123.679 112.603 157.008 1.00 56.08  ? 294 LEU E CD1 1 
ATOM   5052  C  CD2 . LEU B 2 348 ? 122.744 114.815 157.653 1.00 44.27  ? 294 LEU E CD2 1 
ATOM   5053  N  N   . ALA B 2 349 ? 127.846 116.130 158.309 1.00 50.23  ? 295 ALA E N   1 
ATOM   5054  C  CA  . ALA B 2 349 ? 128.917 116.426 159.259 1.00 50.30  ? 295 ALA E CA  1 
ATOM   5055  C  C   . ALA B 2 349 ? 128.863 117.878 159.722 1.00 51.37  ? 295 ALA E C   1 
ATOM   5056  O  O   . ALA B 2 349 ? 128.992 118.164 160.921 1.00 54.75  ? 295 ALA E O   1 
ATOM   5057  C  CB  . ALA B 2 349 ? 130.274 116.114 158.642 1.00 45.32  ? 295 ALA E CB  1 
ATOM   5058  N  N   . LEU B 2 350 ? 128.658 118.808 158.786 1.00 47.72  ? 296 LEU E N   1 
ATOM   5059  C  CA  . LEU B 2 350 ? 128.541 120.213 159.173 1.00 44.64  ? 296 LEU E CA  1 
ATOM   5060  C  C   . LEU B 2 350 ? 127.371 120.434 160.124 1.00 49.61  ? 296 LEU E C   1 
ATOM   5061  O  O   . LEU B 2 350 ? 127.496 121.153 161.124 1.00 53.93  ? 296 LEU E O   1 
ATOM   5062  C  CB  . LEU B 2 350 ? 128.385 121.088 157.934 1.00 50.08  ? 296 LEU E CB  1 
ATOM   5063  C  CG  . LEU B 2 350 ? 128.055 122.554 158.208 1.00 46.74  ? 296 LEU E CG  1 
ATOM   5064  C  CD1 . LEU B 2 350 ? 129.213 123.246 158.889 1.00 43.75  ? 296 LEU E CD1 1 
ATOM   5065  C  CD2 . LEU B 2 350 ? 127.701 123.259 156.931 1.00 50.51  ? 296 LEU E CD2 1 
ATOM   5066  N  N   . LEU B 2 351 ? 126.223 119.822 159.828 1.00 51.34  ? 297 LEU E N   1 
ATOM   5067  C  CA  . LEU B 2 351 ? 125.044 119.985 160.673 1.00 48.90  ? 297 LEU E CA  1 
ATOM   5068  C  C   . LEU B 2 351 ? 125.265 119.391 162.060 1.00 49.30  ? 297 LEU E C   1 
ATOM   5069  O  O   . LEU B 2 351 ? 124.860 119.979 163.072 1.00 52.54  ? 297 LEU E O   1 
ATOM   5070  C  CB  . LEU B 2 351 ? 123.837 119.343 159.993 1.00 47.18  ? 297 LEU E CB  1 
ATOM   5071  C  CG  . LEU B 2 351 ? 122.505 119.350 160.732 1.00 47.64  ? 297 LEU E CG  1 
ATOM   5072  C  CD1 . LEU B 2 351 ? 122.028 120.765 160.973 1.00 47.44  ? 297 LEU E CD1 1 
ATOM   5073  C  CD2 . LEU B 2 351 ? 121.481 118.565 159.940 1.00 51.89  ? 297 LEU E CD2 1 
ATOM   5074  N  N   . GLU B 2 352 ? 125.909 118.226 162.125 1.00 49.64  ? 298 GLU E N   1 
ATOM   5075  C  CA  . GLU B 2 352 ? 126.210 117.616 163.413 1.00 53.30  ? 298 GLU E CA  1 
ATOM   5076  C  C   . GLU B 2 352 ? 127.097 118.523 164.245 1.00 55.57  ? 298 GLU E C   1 
ATOM   5077  O  O   . GLU B 2 352 ? 126.871 118.690 165.450 1.00 57.57  ? 298 GLU E O   1 
ATOM   5078  C  CB  . GLU B 2 352 ? 126.872 116.253 163.209 1.00 54.64  ? 298 GLU E CB  1 
ATOM   5079  C  CG  . GLU B 2 352 ? 127.197 115.505 164.497 1.00 61.86  ? 298 GLU E CG  1 
ATOM   5080  C  CD  . GLU B 2 352 ? 128.572 115.832 165.049 1.00 66.61  ? 298 GLU E CD  1 
ATOM   5081  O  OE1 . GLU B 2 352 ? 129.311 116.609 164.416 1.00 67.73  ? 298 GLU E OE1 1 
ATOM   5082  O  OE2 . GLU B 2 352 ? 128.920 115.312 166.125 1.00 67.84  ? 298 GLU E OE2 1 
ATOM   5083  N  N   . TYR B 2 353 ? 128.116 119.123 163.625 1.00 54.12  ? 299 TYR E N   1 
ATOM   5084  C  CA  . TYR B 2 353 ? 128.948 120.031 164.403 1.00 54.54  ? 299 TYR E CA  1 
ATOM   5085  C  C   . TYR B 2 353 ? 128.170 121.256 164.854 1.00 56.45  ? 299 TYR E C   1 
ATOM   5086  O  O   . TYR B 2 353 ? 128.401 121.758 165.952 1.00 60.94  ? 299 TYR E O   1 
ATOM   5087  C  CB  . TYR B 2 353 ? 130.186 120.489 163.650 1.00 57.56  ? 299 TYR E CB  1 
ATOM   5088  C  CG  . TYR B 2 353 ? 130.865 121.560 164.465 1.00 59.01  ? 299 TYR E CG  1 
ATOM   5089  C  CD1 . TYR B 2 353 ? 131.442 121.253 165.686 1.00 55.77  ? 299 TYR E CD1 1 
ATOM   5090  C  CD2 . TYR B 2 353 ? 130.860 122.883 164.062 1.00 56.44  ? 299 TYR E CD2 1 
ATOM   5091  C  CE1 . TYR B 2 353 ? 132.033 122.221 166.458 1.00 54.84  ? 299 TYR E CE1 1 
ATOM   5092  C  CE2 . TYR B 2 353 ? 131.453 123.859 164.834 1.00 55.75  ? 299 TYR E CE2 1 
ATOM   5093  C  CZ  . TYR B 2 353 ? 132.037 123.519 166.029 1.00 56.66  ? 299 TYR E CZ  1 
ATOM   5094  O  OH  . TYR B 2 353 ? 132.632 124.478 166.804 1.00 63.13  ? 299 TYR E OH  1 
ATOM   5095  N  N   . ALA B 2 354 ? 127.285 121.791 164.013 1.00 53.47  ? 300 ALA E N   1 
ATOM   5096  C  CA  . ALA B 2 354 ? 126.514 122.956 164.442 1.00 50.03  ? 300 ALA E CA  1 
ATOM   5097  C  C   . ALA B 2 354 ? 125.683 122.627 165.674 1.00 57.45  ? 300 ALA E C   1 
ATOM   5098  O  O   . ALA B 2 354 ? 125.667 123.381 166.662 1.00 62.72  ? 300 ALA E O   1 
ATOM   5099  C  CB  . ALA B 2 354 ? 125.624 123.449 163.303 1.00 41.74  ? 300 ALA E CB  1 
ATOM   5100  N  N   . PHE B 2 355 ? 125.018 121.471 165.647 1.00 61.17  ? 301 PHE E N   1 
ATOM   5101  C  CA  . PHE B 2 355 ? 124.216 121.051 166.790 1.00 61.30  ? 301 PHE E CA  1 
ATOM   5102  C  C   . PHE B 2 355 ? 125.075 120.860 168.032 1.00 62.37  ? 301 PHE E C   1 
ATOM   5103  O  O   . PHE B 2 355 ? 124.701 121.295 169.126 1.00 63.43  ? 301 PHE E O   1 
ATOM   5104  C  CB  . PHE B 2 355 ? 123.469 119.765 166.454 1.00 58.58  ? 301 PHE E CB  1 
ATOM   5105  C  CG  . PHE B 2 355 ? 122.622 119.252 167.573 1.00 61.97  ? 301 PHE E CG  1 
ATOM   5106  C  CD1 . PHE B 2 355 ? 121.387 119.806 167.825 1.00 60.74  ? 301 PHE E CD1 1 
ATOM   5107  C  CD2 . PHE B 2 355 ? 123.058 118.214 168.372 1.00 66.86  ? 301 PHE E CD2 1 
ATOM   5108  C  CE1 . PHE B 2 355 ? 120.605 119.338 168.850 1.00 63.35  ? 301 PHE E CE1 1 
ATOM   5109  C  CE2 . PHE B 2 355 ? 122.277 117.744 169.399 1.00 68.83  ? 301 PHE E CE2 1 
ATOM   5110  C  CZ  . PHE B 2 355 ? 121.050 118.308 169.638 1.00 67.10  ? 301 PHE E CZ  1 
ATOM   5111  N  N   . VAL B 2 356 ? 126.235 120.221 167.883 1.00 61.07  ? 302 VAL E N   1 
ATOM   5112  C  CA  . VAL B 2 356 ? 127.110 120.006 169.031 1.00 62.69  ? 302 VAL E CA  1 
ATOM   5113  C  C   . VAL B 2 356 ? 127.630 121.334 169.563 1.00 65.85  ? 302 VAL E C   1 
ATOM   5114  O  O   . VAL B 2 356 ? 127.728 121.540 170.777 1.00 72.28  ? 302 VAL E O   1 
ATOM   5115  C  CB  . VAL B 2 356 ? 128.256 119.053 168.651 1.00 62.76  ? 302 VAL E CB  1 
ATOM   5116  C  CG1 . VAL B 2 356 ? 129.405 119.180 169.628 1.00 64.54  ? 302 VAL E CG1 1 
ATOM   5117  C  CG2 . VAL B 2 356 ? 127.750 117.632 168.623 1.00 64.53  ? 302 VAL E CG2 1 
ATOM   5118  N  N   . ASN B 2 357 ? 127.956 122.257 168.664 1.00 65.70  ? 303 ASN E N   1 
ATOM   5119  C  CA  . ASN B 2 357 ? 128.498 123.545 169.059 1.00 68.29  ? 303 ASN E CA  1 
ATOM   5120  C  C   . ASN B 2 357 ? 127.491 124.353 169.858 1.00 69.75  ? 303 ASN E C   1 
ATOM   5121  O  O   . ASN B 2 357 ? 127.883 125.098 170.762 1.00 75.22  ? 303 ASN E O   1 
ATOM   5122  C  CB  . ASN B 2 357 ? 128.946 124.317 167.820 1.00 65.95  ? 303 ASN E CB  1 
ATOM   5123  C  CG  . ASN B 2 357 ? 129.443 125.702 168.147 1.00 70.36  ? 303 ASN E CG  1 
ATOM   5124  O  OD1 . ASN B 2 357 ? 128.733 126.685 167.961 1.00 75.76  ? 303 ASN E OD1 1 
ATOM   5125  N  ND2 . ASN B 2 357 ? 130.672 125.789 168.635 1.00 64.49  ? 303 ASN E ND2 1 
ATOM   5126  N  N   . TYR B 2 358 ? 126.200 124.244 169.541 1.00 67.08  ? 304 TYR E N   1 
ATOM   5127  C  CA  . TYR B 2 358 ? 125.231 124.957 170.367 1.00 68.62  ? 304 TYR E CA  1 
ATOM   5128  C  C   . TYR B 2 358 ? 125.152 124.374 171.775 1.00 74.09  ? 304 TYR E C   1 
ATOM   5129  O  O   . TYR B 2 358 ? 125.252 125.108 172.763 1.00 81.83  ? 304 TYR E O   1 
ATOM   5130  C  CB  . TYR B 2 358 ? 123.848 124.954 169.732 1.00 70.48  ? 304 TYR E CB  1 
ATOM   5131  C  CG  . TYR B 2 358 ? 122.832 125.582 170.653 1.00 72.06  ? 304 TYR E CG  1 
ATOM   5132  C  CD1 . TYR B 2 358 ? 122.818 126.952 170.864 1.00 72.72  ? 304 TYR E CD1 1 
ATOM   5133  C  CD2 . TYR B 2 358 ? 121.912 124.807 171.340 1.00 74.94  ? 304 TYR E CD2 1 
ATOM   5134  C  CE1 . TYR B 2 358 ? 121.907 127.532 171.713 1.00 77.23  ? 304 TYR E CE1 1 
ATOM   5135  C  CE2 . TYR B 2 358 ? 120.997 125.380 172.194 1.00 78.25  ? 304 TYR E CE2 1 
ATOM   5136  C  CZ  . TYR B 2 358 ? 120.997 126.743 172.376 1.00 81.26  ? 304 TYR E CZ  1 
ATOM   5137  O  OH  . TYR B 2 358 ? 120.083 127.318 173.227 1.00 84.16  ? 304 TYR E OH  1 
ATOM   5138  N  N   . ILE B 2 359 ? 124.971 123.053 171.893 1.00 74.24  ? 305 ILE E N   1 
ATOM   5139  C  CA  . ILE B 2 359 ? 124.620 122.459 173.182 1.00 75.67  ? 305 ILE E CA  1 
ATOM   5140  C  C   . ILE B 2 359 ? 125.827 122.127 174.040 1.00 81.64  ? 305 ILE E C   1 
ATOM   5141  O  O   . ILE B 2 359 ? 125.659 121.559 175.127 1.00 84.36  ? 305 ILE E O   1 
ATOM   5142  C  CB  . ILE B 2 359 ? 123.792 121.168 173.033 1.00 69.78  ? 305 ILE E CB  1 
ATOM   5143  C  CG1 . ILE B 2 359 ? 124.627 120.077 172.375 1.00 68.60  ? 305 ILE E CG1 1 
ATOM   5144  C  CG2 . ILE B 2 359 ? 122.525 121.428 172.249 1.00 69.64  ? 305 ILE E CG2 1 
ATOM   5145  C  CD1 . ILE B 2 359 ? 123.969 118.733 172.393 1.00 75.62  ? 305 ILE E CD1 1 
ATOM   5146  N  N   . PHE B 2 360 ? 127.040 122.447 173.590 1.00 82.60  ? 306 PHE E N   1 
ATOM   5147  C  CA  . PHE B 2 360 ? 128.210 122.180 174.416 1.00 85.09  ? 306 PHE E CA  1 
ATOM   5148  C  C   . PHE B 2 360 ? 128.213 123.035 175.678 1.00 90.93  ? 306 PHE E C   1 
ATOM   5149  O  O   . PHE B 2 360 ? 128.683 122.586 176.728 1.00 89.17  ? 306 PHE E O   1 
ATOM   5150  C  CB  . PHE B 2 360 ? 129.485 122.409 173.603 1.00 88.45  ? 306 PHE E CB  1 
ATOM   5151  C  CG  . PHE B 2 360 ? 130.672 122.789 174.434 1.00 99.14  ? 306 PHE E CG  1 
ATOM   5152  C  CD1 . PHE B 2 360 ? 131.260 121.873 175.289 1.00 98.07  ? 306 PHE E CD1 1 
ATOM   5153  C  CD2 . PHE B 2 360 ? 131.202 124.066 174.359 1.00 97.34  ? 306 PHE E CD2 1 
ATOM   5154  C  CE1 . PHE B 2 360 ? 132.345 122.228 176.063 1.00 99.75  ? 306 PHE E CE1 1 
ATOM   5155  C  CE2 . PHE B 2 360 ? 132.290 124.424 175.124 1.00 99.34  ? 306 PHE E CE2 1 
ATOM   5156  C  CZ  . PHE B 2 360 ? 132.863 123.503 175.978 1.00 103.59 ? 306 PHE E CZ  1 
ATOM   5157  N  N   . PHE B 2 361 ? 127.686 124.257 175.598 1.00 93.68  ? 307 PHE E N   1 
ATOM   5158  C  CA  . PHE B 2 361 ? 127.752 125.170 176.734 1.00 94.54  ? 307 PHE E CA  1 
ATOM   5159  C  C   . PHE B 2 361 ? 126.978 124.636 177.930 1.00 91.48  ? 307 PHE E C   1 
ATOM   5160  O  O   . PHE B 2 361 ? 127.434 124.747 179.073 1.00 92.53  ? 307 PHE E O   1 
ATOM   5161  C  CB  . PHE B 2 361 ? 127.226 126.544 176.323 1.00 94.56  ? 307 PHE E CB  1 
ATOM   5162  C  CG  . PHE B 2 361 ? 128.077 127.231 175.297 1.00 99.78  ? 307 PHE E CG  1 
ATOM   5163  C  CD1 . PHE B 2 361 ? 129.432 126.962 175.210 1.00 103.40 ? 307 PHE E CD1 1 
ATOM   5164  C  CD2 . PHE B 2 361 ? 127.526 128.144 174.421 1.00 99.86  ? 307 PHE E CD2 1 
ATOM   5165  C  CE1 . PHE B 2 361 ? 130.218 127.592 174.269 1.00 104.24 ? 307 PHE E CE1 1 
ATOM   5166  C  CE2 . PHE B 2 361 ? 128.308 128.775 173.480 1.00 105.41 ? 307 PHE E CE2 1 
ATOM   5167  C  CZ  . PHE B 2 361 ? 129.656 128.499 173.404 1.00 104.65 ? 307 PHE E CZ  1 
ATOM   5168  N  N   . SER B 2 362 ? 125.808 124.052 177.690 1.00 88.12  ? 308 SER E N   1 
ATOM   5169  C  CA  . SER B 2 362 ? 124.951 123.583 178.768 1.00 87.82  ? 308 SER E CA  1 
ATOM   5170  C  C   . SER B 2 362 ? 125.064 122.091 179.033 1.00 90.01  ? 308 SER E C   1 
ATOM   5171  O  O   . SER B 2 362 ? 124.877 121.666 180.176 1.00 90.34  ? 308 SER E O   1 
ATOM   5172  C  CB  . SER B 2 362 ? 123.489 123.927 178.464 1.00 82.01  ? 308 SER E CB  1 
ATOM   5173  O  OG  . SER B 2 362 ? 122.640 123.523 179.523 1.00 85.25  ? 308 SER E OG  1 
ATOM   5174  N  N   . GLN B 2 363 ? 125.360 121.284 178.016 1.00 90.40  ? 309 GLN E N   1 
ATOM   5175  C  CA  . GLN B 2 363 ? 125.394 119.826 178.139 1.00 89.30  ? 309 GLN E CA  1 
ATOM   5176  C  C   . GLN B 2 363 ? 126.686 119.284 177.540 1.00 88.90  ? 309 GLN E C   1 
ATOM   5177  O  O   . GLN B 2 363 ? 126.678 118.681 176.461 1.00 88.11  ? 309 GLN E O   1 
ATOM   5178  C  CB  . GLN B 2 363 ? 124.179 119.200 177.457 1.00 86.65  ? 309 GLN E CB  1 
ATOM   5179  C  CG  . GLN B 2 363 ? 122.851 119.687 177.987 1.00 89.50  ? 309 GLN E CG  1 
ATOM   5180  C  CD  . GLN B 2 363 ? 121.683 119.101 177.230 1.00 91.84  ? 309 GLN E CD  1 
ATOM   5181  O  OE1 . GLN B 2 363 ? 121.823 118.684 176.083 1.00 89.88  ? 309 GLN E OE1 1 
ATOM   5182  N  NE2 . GLN B 2 363 ? 120.522 119.058 177.871 1.00 89.66  ? 309 GLN E NE2 1 
ATOM   5183  N  N   . PRO B 2 364 ? 127.821 119.481 178.218 1.00 90.14  ? 310 PRO E N   1 
ATOM   5184  C  CA  . PRO B 2 364 ? 129.092 118.987 177.660 1.00 90.19  ? 310 PRO E CA  1 
ATOM   5185  C  C   . PRO B 2 364 ? 129.114 117.486 177.434 1.00 86.69  ? 310 PRO E C   1 
ATOM   5186  O  O   . PRO B 2 364 ? 129.670 117.018 176.429 1.00 85.99  ? 310 PRO E O   1 
ATOM   5187  C  CB  . PRO B 2 364 ? 130.123 119.410 178.716 1.00 89.54  ? 310 PRO E CB  1 
ATOM   5188  C  CG  . PRO B 2 364 ? 129.460 120.481 179.506 1.00 89.09  ? 310 PRO E CG  1 
ATOM   5189  C  CD  . PRO B 2 364 ? 128.010 120.145 179.517 1.00 87.55  ? 310 PRO E CD  1 
ATOM   5190  N  N   . ALA B 2 365 ? 128.519 116.717 178.348 1.00 82.51  ? 311 ALA E N   1 
ATOM   5191  C  CA  . ALA B 2 365 ? 128.562 115.264 178.235 1.00 75.90  ? 311 ALA E CA  1 
ATOM   5192  C  C   . ALA B 2 365 ? 127.823 114.785 176.996 1.00 77.44  ? 311 ALA E C   1 
ATOM   5193  O  O   . ALA B 2 365 ? 128.293 113.886 176.291 1.00 75.90  ? 311 ALA E O   1 
ATOM   5194  C  CB  . ALA B 2 365 ? 127.973 114.621 179.488 1.00 72.60  ? 311 ALA E CB  1 
ATOM   5195  N  N   . ARG B 2 366 ? 126.663 115.376 176.712 1.00 78.71  ? 312 ARG E N   1 
ATOM   5196  C  CA  . ARG B 2 366 ? 125.899 114.967 175.541 1.00 76.60  ? 312 ARG E CA  1 
ATOM   5197  C  C   . ARG B 2 366 ? 126.648 115.289 174.254 1.00 76.23  ? 312 ARG E C   1 
ATOM   5198  O  O   . ARG B 2 366 ? 126.663 114.481 173.320 1.00 77.05  ? 312 ARG E O   1 
ATOM   5199  C  CB  . ARG B 2 366 ? 124.531 115.638 175.552 1.00 74.69  ? 312 ARG E CB  1 
ATOM   5200  C  CG  . ARG B 2 366 ? 123.529 115.000 174.626 1.00 78.11  ? 312 ARG E CG  1 
ATOM   5201  C  CD  . ARG B 2 366 ? 122.255 115.803 174.590 1.00 82.80  ? 312 ARG E CD  1 
ATOM   5202  N  NE  . ARG B 2 366 ? 121.298 115.261 173.636 1.00 86.19  ? 312 ARG E NE  1 
ATOM   5203  C  CZ  . ARG B 2 366 ? 120.271 115.939 173.147 1.00 90.07  ? 312 ARG E CZ  1 
ATOM   5204  N  NH1 . ARG B 2 366 ? 120.048 117.197 173.491 1.00 84.84  ? 312 ARG E NH1 1 
ATOM   5205  N  NH2 . ARG B 2 366 ? 119.453 115.344 172.285 1.00 92.26  ? 312 ARG E NH2 1 
ATOM   5206  N  N   . ALA B 2 367 ? 127.280 116.461 174.188 1.00 75.04  ? 313 ALA E N   1 
ATOM   5207  C  CA  . ALA B 2 367 ? 128.054 116.812 173.003 1.00 71.20  ? 313 ALA E CA  1 
ATOM   5208  C  C   . ALA B 2 367 ? 129.225 115.860 172.804 1.00 74.46  ? 313 ALA E C   1 
ATOM   5209  O  O   . ALA B 2 367 ? 129.491 115.413 171.679 1.00 75.98  ? 313 ALA E O   1 
ATOM   5210  C  CB  . ALA B 2 367 ? 128.548 118.252 173.110 1.00 77.55  ? 313 ALA E CB  1 
ATOM   5211  N  N   . ALA B 2 368 ? 129.940 115.538 173.884 1.00 76.09  ? 314 ALA E N   1 
ATOM   5212  C  CA  . ALA B 2 368 ? 131.057 114.608 173.767 1.00 71.41  ? 314 ALA E CA  1 
ATOM   5213  C  C   . ALA B 2 368 ? 130.579 113.233 173.329 1.00 74.52  ? 314 ALA E C   1 
ATOM   5214  O  O   . ALA B 2 368 ? 131.231 112.570 172.514 1.00 78.57  ? 314 ALA E O   1 
ATOM   5215  C  CB  . ALA B 2 368 ? 131.811 114.519 175.090 1.00 68.85  ? 314 ALA E CB  1 
ATOM   5216  N  N   . ALA B 2 369 ? 129.437 112.787 173.856 1.00 75.32  ? 422 ALA E N   1 
ATOM   5217  C  CA  . ALA B 2 369 ? 128.891 111.499 173.448 1.00 73.96  ? 422 ALA E CA  1 
ATOM   5218  C  C   . ALA B 2 369 ? 128.511 111.502 171.974 1.00 75.01  ? 422 ALA E C   1 
ATOM   5219  O  O   . ALA B 2 369 ? 128.747 110.519 171.263 1.00 75.60  ? 422 ALA E O   1 
ATOM   5220  C  CB  . ALA B 2 369 ? 127.685 111.146 174.314 1.00 71.14  ? 422 ALA E CB  1 
ATOM   5221  N  N   . ILE B 2 370 ? 127.921 112.599 171.495 1.00 72.55  ? 423 ILE E N   1 
ATOM   5222  C  CA  . ILE B 2 370 ? 127.547 112.676 170.086 1.00 66.99  ? 423 ILE E CA  1 
ATOM   5223  C  C   . ILE B 2 370 ? 128.784 112.625 169.200 1.00 66.19  ? 423 ILE E C   1 
ATOM   5224  O  O   . ILE B 2 370 ? 128.800 111.930 168.178 1.00 71.41  ? 423 ILE E O   1 
ATOM   5225  C  CB  . ILE B 2 370 ? 126.703 113.934 169.815 1.00 65.60  ? 423 ILE E CB  1 
ATOM   5226  C  CG1 . ILE B 2 370 ? 125.346 113.819 170.500 1.00 63.56  ? 423 ILE E CG1 1 
ATOM   5227  C  CG2 . ILE B 2 370 ? 126.504 114.124 168.329 1.00 61.03  ? 423 ILE E CG2 1 
ATOM   5228  C  CD1 . ILE B 2 370 ? 124.456 115.011 170.281 1.00 61.56  ? 423 ILE E CD1 1 
ATOM   5229  N  N   . ASP B 2 371 ? 129.842 113.349 169.574 1.00 67.25  ? 424 ASP E N   1 
ATOM   5230  C  CA  . ASP B 2 371 ? 131.073 113.290 168.787 1.00 69.87  ? 424 ASP E CA  1 
ATOM   5231  C  C   . ASP B 2 371 ? 131.665 111.886 168.785 1.00 72.54  ? 424 ASP E C   1 
ATOM   5232  O  O   . ASP B 2 371 ? 132.098 111.380 167.739 1.00 73.25  ? 424 ASP E O   1 
ATOM   5233  C  CB  . ASP B 2 371 ? 132.096 114.287 169.326 1.00 70.63  ? 424 ASP E CB  1 
ATOM   5234  C  CG  . ASP B 2 371 ? 131.878 115.681 168.803 1.00 76.65  ? 424 ASP E CG  1 
ATOM   5235  O  OD1 . ASP B 2 371 ? 130.875 115.899 168.098 1.00 77.94  ? 424 ASP E OD1 1 
ATOM   5236  O  OD2 . ASP B 2 371 ? 132.712 116.561 169.093 1.00 83.27  ? 424 ASP E OD2 1 
ATOM   5237  N  N   . ARG B 2 372 ? 131.695 111.244 169.955 1.00 74.33  ? 425 ARG E N   1 
ATOM   5238  C  CA  . ARG B 2 372 ? 132.247 109.900 170.057 1.00 73.33  ? 425 ARG E CA  1 
ATOM   5239  C  C   . ARG B 2 372 ? 131.469 108.921 169.192 1.00 75.68  ? 425 ARG E C   1 
ATOM   5240  O  O   . ARG B 2 372 ? 132.057 108.040 168.557 1.00 74.23  ? 425 ARG E O   1 
ATOM   5241  C  CB  . ARG B 2 372 ? 132.244 109.455 171.518 1.00 77.75  ? 425 ARG E CB  1 
ATOM   5242  C  CG  . ARG B 2 372 ? 132.574 107.991 171.731 1.00 85.03  ? 425 ARG E CG  1 
ATOM   5243  C  CD  . ARG B 2 372 ? 132.288 107.574 173.161 1.00 90.23  ? 425 ARG E CD  1 
ATOM   5244  N  NE  . ARG B 2 372 ? 132.530 106.154 173.374 1.00 109.37 ? 425 ARG E NE  1 
ATOM   5245  C  CZ  . ARG B 2 372 ? 132.437 105.546 174.549 1.00 114.17 ? 425 ARG E CZ  1 
ATOM   5246  N  NH1 . ARG B 2 372 ? 132.110 106.208 175.645 1.00 114.43 ? 425 ARG E NH1 1 
ATOM   5247  N  NH2 . ARG B 2 372 ? 132.682 104.240 174.625 1.00 111.60 ? 425 ARG E NH2 1 
ATOM   5248  N  N   . TRP B 2 373 ? 130.143 109.054 169.160 1.00 75.39  ? 426 TRP E N   1 
ATOM   5249  C  CA  . TRP B 2 373 ? 129.342 108.177 168.314 1.00 73.13  ? 426 TRP E CA  1 
ATOM   5250  C  C   . TRP B 2 373 ? 129.556 108.472 166.837 1.00 69.48  ? 426 TRP E C   1 
ATOM   5251  O  O   . TRP B 2 373 ? 129.608 107.548 166.020 1.00 72.62  ? 426 TRP E O   1 
ATOM   5252  C  CB  . TRP B 2 373 ? 127.866 108.301 168.672 1.00 77.08  ? 426 TRP E CB  1 
ATOM   5253  C  CG  . TRP B 2 373 ? 127.464 107.391 169.774 1.00 92.99  ? 426 TRP E CG  1 
ATOM   5254  C  CD1 . TRP B 2 373 ? 127.311 107.714 171.087 1.00 94.84  ? 426 TRP E CD1 1 
ATOM   5255  C  CD2 . TRP B 2 373 ? 127.172 105.997 169.665 1.00 101.09 ? 426 TRP E CD2 1 
ATOM   5256  N  NE1 . TRP B 2 373 ? 126.933 106.607 171.805 1.00 101.47 ? 426 TRP E NE1 1 
ATOM   5257  C  CE2 . TRP B 2 373 ? 126.841 105.539 170.953 1.00 105.43 ? 426 TRP E CE2 1 
ATOM   5258  C  CE3 . TRP B 2 373 ? 127.154 105.091 168.602 1.00 96.74  ? 426 TRP E CE3 1 
ATOM   5259  C  CZ2 . TRP B 2 373 ? 126.497 104.215 171.208 1.00 103.95 ? 426 TRP E CZ2 1 
ATOM   5260  C  CZ3 . TRP B 2 373 ? 126.812 103.778 168.857 1.00 105.36 ? 426 TRP E CZ3 1 
ATOM   5261  C  CH2 . TRP B 2 373 ? 126.488 103.352 170.148 1.00 105.61 ? 426 TRP E CH2 1 
ATOM   5262  N  N   . SER B 2 374 ? 129.671 109.750 166.474 1.00 67.77  ? 427 SER E N   1 
ATOM   5263  C  CA  . SER B 2 374 ? 129.840 110.106 165.070 1.00 63.67  ? 427 SER E CA  1 
ATOM   5264  C  C   . SER B 2 374 ? 131.148 109.562 164.520 1.00 64.73  ? 427 SER E C   1 
ATOM   5265  O  O   . SER B 2 374 ? 131.203 109.114 163.365 1.00 65.27  ? 427 SER E O   1 
ATOM   5266  C  CB  . SER B 2 374 ? 129.770 111.619 164.904 1.00 59.40  ? 427 SER E CB  1 
ATOM   5267  O  OG  . SER B 2 374 ? 128.462 112.089 165.165 1.00 56.28  ? 427 SER E OG  1 
ATOM   5268  N  N   . ARG B 2 375 ? 132.201 109.563 165.346 1.00 63.99  ? 428 ARG E N   1 
ATOM   5269  C  CA  . ARG B 2 375 ? 133.493 109.026 164.922 1.00 65.85  ? 428 ARG E CA  1 
ATOM   5270  C  C   . ARG B 2 375 ? 133.372 107.614 164.368 1.00 70.05  ? 428 ARG E C   1 
ATOM   5271  O  O   . ARG B 2 375 ? 134.120 107.237 163.459 1.00 69.20  ? 428 ARG E O   1 
ATOM   5272  C  CB  . ARG B 2 375 ? 134.476 109.012 166.091 1.00 66.46  ? 428 ARG E CB  1 
ATOM   5273  C  CG  . ARG B 2 375 ? 134.979 110.359 166.527 1.00 68.58  ? 428 ARG E CG  1 
ATOM   5274  C  CD  . ARG B 2 375 ? 135.806 110.228 167.789 1.00 68.33  ? 428 ARG E CD  1 
ATOM   5275  N  NE  . ARG B 2 375 ? 136.192 111.527 168.316 1.00 72.66  ? 428 ARG E NE  1 
ATOM   5276  C  CZ  . ARG B 2 375 ? 136.637 111.730 169.546 1.00 74.58  ? 428 ARG E CZ  1 
ATOM   5277  N  NH1 . ARG B 2 375 ? 136.767 110.734 170.404 1.00 78.78  ? 428 ARG E NH1 1 
ATOM   5278  N  NH2 . ARG B 2 375 ? 136.955 112.963 169.924 1.00 73.06  ? 428 ARG E NH2 1 
ATOM   5279  N  N   . ILE B 2 376 ? 132.459 106.815 164.908 1.00 69.77  ? 429 ILE E N   1 
ATOM   5280  C  CA  . ILE B 2 376 ? 132.244 105.464 164.407 1.00 63.29  ? 429 ILE E CA  1 
ATOM   5281  C  C   . ILE B 2 376 ? 131.173 105.435 163.326 1.00 64.56  ? 429 ILE E C   1 
ATOM   5282  O  O   . ILE B 2 376 ? 131.311 104.727 162.327 1.00 66.83  ? 429 ILE E O   1 
ATOM   5283  C  CB  . ILE B 2 376 ? 131.889 104.531 165.579 1.00 56.73  ? 429 ILE E CB  1 
ATOM   5284  C  CG1 . ILE B 2 376 ? 133.093 104.382 166.506 1.00 65.44  ? 429 ILE E CG1 1 
ATOM   5285  C  CG2 . ILE B 2 376 ? 131.428 103.182 165.071 1.00 54.93  ? 429 ILE E CG2 1 
ATOM   5286  C  CD1 . ILE B 2 376 ? 132.789 103.666 167.795 1.00 73.83  ? 429 ILE E CD1 1 
ATOM   5287  N  N   . VAL B 2 377 ? 130.105 106.213 163.494 1.00 64.66  ? 430 VAL E N   1 
ATOM   5288  C  CA  . VAL B 2 377 ? 128.951 106.092 162.611 1.00 63.38  ? 430 VAL E CA  1 
ATOM   5289  C  C   . VAL B 2 377 ? 129.297 106.535 161.195 1.00 67.84  ? 430 VAL E C   1 
ATOM   5290  O  O   . VAL B 2 377 ? 128.945 105.862 160.220 1.00 71.25  ? 430 VAL E O   1 
ATOM   5291  C  CB  . VAL B 2 377 ? 127.760 106.882 163.176 1.00 64.20  ? 430 VAL E CB  1 
ATOM   5292  C  CG1 . VAL B 2 377 ? 126.706 107.086 162.111 1.00 60.50  ? 430 VAL E CG1 1 
ATOM   5293  C  CG2 . VAL B 2 377 ? 127.171 106.151 164.359 1.00 66.89  ? 430 VAL E CG2 1 
ATOM   5294  N  N   . PHE B 2 378 ? 129.974 107.674 161.051 1.00 67.60  ? 431 PHE E N   1 
ATOM   5295  C  CA  . PHE B 2 378 ? 130.195 108.204 159.705 1.00 66.12  ? 431 PHE E CA  1 
ATOM   5296  C  C   . PHE B 2 378 ? 131.074 107.310 158.834 1.00 68.60  ? 431 PHE E C   1 
ATOM   5297  O  O   . PHE B 2 378 ? 130.668 107.009 157.696 1.00 71.50  ? 431 PHE E O   1 
ATOM   5298  C  CB  . PHE B 2 378 ? 130.736 109.632 159.799 1.00 58.89  ? 431 PHE E CB  1 
ATOM   5299  C  CG  . PHE B 2 378 ? 129.665 110.675 159.880 1.00 59.51  ? 431 PHE E CG  1 
ATOM   5300  C  CD1 . PHE B 2 378 ? 128.948 110.860 161.043 1.00 60.25  ? 431 PHE E CD1 1 
ATOM   5301  C  CD2 . PHE B 2 378 ? 129.376 111.471 158.793 1.00 57.54  ? 431 PHE E CD2 1 
ATOM   5302  C  CE1 . PHE B 2 378 ? 127.963 111.819 161.118 1.00 58.93  ? 431 PHE E CE1 1 
ATOM   5303  C  CE2 . PHE B 2 378 ? 128.396 112.429 158.867 1.00 55.87  ? 431 PHE E CE2 1 
ATOM   5304  C  CZ  . PHE B 2 378 ? 127.691 112.604 160.030 1.00 54.92  ? 431 PHE E CZ  1 
ATOM   5305  N  N   . PRO B 2 379 ? 132.258 106.857 159.273 1.00 65.81  ? 432 PRO E N   1 
ATOM   5306  C  CA  . PRO B 2 379 ? 133.037 105.944 158.419 1.00 62.13  ? 432 PRO E CA  1 
ATOM   5307  C  C   . PRO B 2 379 ? 132.317 104.652 158.080 1.00 67.73  ? 432 PRO E C   1 
ATOM   5308  O  O   . PRO B 2 379 ? 132.453 104.153 156.959 1.00 73.27  ? 432 PRO E O   1 
ATOM   5309  C  CB  . PRO B 2 379 ? 134.295 105.681 159.254 1.00 58.96  ? 432 PRO E CB  1 
ATOM   5310  C  CG  . PRO B 2 379 ? 134.418 106.859 160.119 1.00 62.13  ? 432 PRO E CG  1 
ATOM   5311  C  CD  . PRO B 2 379 ? 133.023 107.250 160.468 1.00 65.31  ? 432 PRO E CD  1 
ATOM   5312  N  N   . PHE B 2 380 ? 131.547 104.099 159.017 1.00 66.99  ? 433 PHE E N   1 
ATOM   5313  C  CA  . PHE B 2 380 ? 130.839 102.849 158.759 1.00 68.79  ? 433 PHE E CA  1 
ATOM   5314  C  C   . PHE B 2 380 ? 129.778 103.027 157.678 1.00 68.60  ? 433 PHE E C   1 
ATOM   5315  O  O   . PHE B 2 380 ? 129.692 102.229 156.734 1.00 72.19  ? 433 PHE E O   1 
ATOM   5316  C  CB  . PHE B 2 380 ? 130.219 102.339 160.060 1.00 69.99  ? 433 PHE E CB  1 
ATOM   5317  C  CG  . PHE B 2 380 ? 129.423 101.080 159.906 1.00 76.13  ? 433 PHE E CG  1 
ATOM   5318  C  CD1 . PHE B 2 380 ? 130.051 99.851  159.877 1.00 79.57  ? 433 PHE E CD1 1 
ATOM   5319  C  CD2 . PHE B 2 380 ? 128.046 101.125 159.808 1.00 73.21  ? 433 PHE E CD2 1 
ATOM   5320  C  CE1 . PHE B 2 380 ? 129.321 98.690  159.740 1.00 80.40  ? 433 PHE E CE1 1 
ATOM   5321  C  CE2 . PHE B 2 380 ? 127.311 99.970  159.670 1.00 74.21  ? 433 PHE E CE2 1 
ATOM   5322  C  CZ  . PHE B 2 380 ? 127.949 98.750  159.636 1.00 77.58  ? 433 PHE E CZ  1 
ATOM   5323  N  N   . THR B 2 381 ? 128.966 104.077 157.794 1.00 64.29  ? 434 THR E N   1 
ATOM   5324  C  CA  . THR B 2 381 ? 127.943 104.326 156.788 1.00 69.14  ? 434 THR E CA  1 
ATOM   5325  C  C   . THR B 2 381 ? 128.563 104.647 155.435 1.00 72.09  ? 434 THR E C   1 
ATOM   5326  O  O   . THR B 2 381 ? 128.046 104.225 154.395 1.00 76.77  ? 434 THR E O   1 
ATOM   5327  C  CB  . THR B 2 381 ? 127.022 105.458 157.236 1.00 71.80  ? 434 THR E CB  1 
ATOM   5328  O  OG1 . THR B 2 381 ? 127.813 106.567 157.675 1.00 75.04  ? 434 THR E OG1 1 
ATOM   5329  C  CG2 . THR B 2 381 ? 126.133 104.998 158.366 1.00 69.63  ? 434 THR E CG2 1 
ATOM   5330  N  N   . PHE B 2 382 ? 129.670 105.393 155.420 1.00 68.95  ? 435 PHE E N   1 
ATOM   5331  C  CA  . PHE B 2 382 ? 130.309 105.684 154.142 1.00 65.77  ? 435 PHE E CA  1 
ATOM   5332  C  C   . PHE B 2 382 ? 130.876 104.422 153.501 1.00 70.40  ? 435 PHE E C   1 
ATOM   5333  O  O   . PHE B 2 382 ? 130.799 104.253 152.278 1.00 73.63  ? 435 PHE E O   1 
ATOM   5334  C  CB  . PHE B 2 382 ? 131.403 106.731 154.315 1.00 65.27  ? 435 PHE E CB  1 
ATOM   5335  C  CG  . PHE B 2 382 ? 131.892 107.295 153.021 1.00 65.67  ? 435 PHE E CG  1 
ATOM   5336  C  CD1 . PHE B 2 382 ? 131.008 107.873 152.135 1.00 66.21  ? 435 PHE E CD1 1 
ATOM   5337  C  CD2 . PHE B 2 382 ? 133.230 107.246 152.687 1.00 68.66  ? 435 PHE E CD2 1 
ATOM   5338  C  CE1 . PHE B 2 382 ? 131.445 108.387 150.942 1.00 67.04  ? 435 PHE E CE1 1 
ATOM   5339  C  CE2 . PHE B 2 382 ? 133.673 107.767 151.492 1.00 66.12  ? 435 PHE E CE2 1 
ATOM   5340  C  CZ  . PHE B 2 382 ? 132.779 108.335 150.620 1.00 64.19  ? 435 PHE E CZ  1 
ATOM   5341  N  N   . SER B 2 383 ? 131.453 103.528 154.304 1.00 71.85  ? 436 SER E N   1 
ATOM   5342  C  CA  . SER B 2 383 ? 131.946 102.271 153.756 1.00 73.79  ? 436 SER E CA  1 
ATOM   5343  C  C   . SER B 2 383 ? 130.808 101.439 153.186 1.00 73.39  ? 436 SER E C   1 
ATOM   5344  O  O   . SER B 2 383 ? 130.952 100.824 152.123 1.00 76.73  ? 436 SER E O   1 
ATOM   5345  C  CB  . SER B 2 383 ? 132.699 101.490 154.830 1.00 73.34  ? 436 SER E CB  1 
ATOM   5346  O  OG  . SER B 2 383 ? 133.861 102.184 155.242 1.00 75.83  ? 436 SER E OG  1 
ATOM   5347  N  N   . LEU B 2 384 ? 129.668 101.402 153.878 1.00 68.81  ? 437 LEU E N   1 
ATOM   5348  C  CA  . LEU B 2 384 ? 128.526 100.664 153.344 1.00 70.98  ? 437 LEU E CA  1 
ATOM   5349  C  C   . LEU B 2 384 ? 128.022 101.288 152.049 1.00 75.66  ? 437 LEU E C   1 
ATOM   5350  O  O   . LEU B 2 384 ? 127.637 100.574 151.115 1.00 81.30  ? 437 LEU E O   1 
ATOM   5351  C  CB  . LEU B 2 384 ? 127.405 100.588 154.375 1.00 68.80  ? 437 LEU E CB  1 
ATOM   5352  C  CG  . LEU B 2 384 ? 127.677 99.711  155.595 1.00 71.79  ? 437 LEU E CG  1 
ATOM   5353  C  CD1 . LEU B 2 384 ? 126.367 99.278  156.222 1.00 71.97  ? 437 LEU E CD1 1 
ATOM   5354  C  CD2 . LEU B 2 384 ? 128.524 98.508  155.222 1.00 73.78  ? 437 LEU E CD2 1 
ATOM   5355  N  N   . PHE B 2 385 ? 128.007 102.619 151.976 1.00 74.30  ? 438 PHE E N   1 
ATOM   5356  C  CA  . PHE B 2 385 ? 127.609 103.285 150.741 1.00 73.36  ? 438 PHE E CA  1 
ATOM   5357  C  C   . PHE B 2 385 ? 128.543 102.918 149.594 1.00 74.01  ? 438 PHE E C   1 
ATOM   5358  O  O   . PHE B 2 385 ? 128.088 102.632 148.480 1.00 72.51  ? 438 PHE E O   1 
ATOM   5359  C  CB  . PHE B 2 385 ? 127.585 104.795 150.956 1.00 70.14  ? 438 PHE E CB  1 
ATOM   5360  C  CG  . PHE B 2 385 ? 127.161 105.575 149.751 1.00 72.62  ? 438 PHE E CG  1 
ATOM   5361  C  CD1 . PHE B 2 385 ? 125.824 105.818 149.508 1.00 70.09  ? 438 PHE E CD1 1 
ATOM   5362  C  CD2 . PHE B 2 385 ? 128.100 106.087 148.873 1.00 68.48  ? 438 PHE E CD2 1 
ATOM   5363  C  CE1 . PHE B 2 385 ? 125.433 106.544 148.407 1.00 68.84  ? 438 PHE E CE1 1 
ATOM   5364  C  CE2 . PHE B 2 385 ? 127.712 106.809 147.773 1.00 69.38  ? 438 PHE E CE2 1 
ATOM   5365  C  CZ  . PHE B 2 385 ? 126.379 107.037 147.538 1.00 72.53  ? 438 PHE E CZ  1 
ATOM   5366  N  N   . ASN B 2 386 ? 129.853 102.915 149.853 1.00 71.51  ? 439 ASN E N   1 
ATOM   5367  C  CA  . ASN B 2 386 ? 130.809 102.514 148.826 1.00 74.47  ? 439 ASN E CA  1 
ATOM   5368  C  C   . ASN B 2 386 ? 130.578 101.076 148.387 1.00 80.20  ? 439 ASN E C   1 
ATOM   5369  O  O   . ASN B 2 386 ? 130.645 100.767 147.193 1.00 84.09  ? 439 ASN E O   1 
ATOM   5370  C  CB  . ASN B 2 386 ? 132.240 102.676 149.334 1.00 73.30  ? 439 ASN E CB  1 
ATOM   5371  C  CG  . ASN B 2 386 ? 132.760 104.083 149.179 1.00 75.78  ? 439 ASN E CG  1 
ATOM   5372  O  OD1 . ASN B 2 386 ? 132.453 104.767 148.209 1.00 79.18  ? 439 ASN E OD1 1 
ATOM   5373  N  ND2 . ASN B 2 386 ? 133.564 104.520 150.135 1.00 79.10  ? 439 ASN E ND2 1 
ATOM   5374  N  N   . LEU B 2 387 ? 130.334 100.177 149.340 1.00 79.17  ? 440 LEU E N   1 
ATOM   5375  C  CA  . LEU B 2 387 ? 130.100 98.782  148.986 1.00 75.35  ? 440 LEU E CA  1 
ATOM   5376  C  C   . LEU B 2 387 ? 128.870 98.641  148.103 1.00 75.79  ? 440 LEU E C   1 
ATOM   5377  O  O   . LEU B 2 387 ? 128.907 97.961  147.070 1.00 80.13  ? 440 LEU E O   1 
ATOM   5378  C  CB  . LEU B 2 387 ? 129.951 97.935  150.245 1.00 76.75  ? 440 LEU E CB  1 
ATOM   5379  C  CG  . LEU B 2 387 ? 131.152 97.072  150.609 1.00 84.17  ? 440 LEU E CG  1 
ATOM   5380  C  CD1 . LEU B 2 387 ? 132.371 97.938  150.878 1.00 84.68  ? 440 LEU E CD1 1 
ATOM   5381  C  CD2 . LEU B 2 387 ? 130.818 96.212  151.811 1.00 89.50  ? 440 LEU E CD2 1 
ATOM   5382  N  N   . VAL B 2 388 ? 127.773 99.296  148.483 1.00 71.05  ? 441 VAL E N   1 
ATOM   5383  C  CA  . VAL B 2 388 ? 126.550 99.214  147.690 1.00 74.41  ? 441 VAL E CA  1 
ATOM   5384  C  C   . VAL B 2 388 ? 126.791 99.751  146.285 1.00 80.39  ? 441 VAL E C   1 
ATOM   5385  O  O   . VAL B 2 388 ? 126.403 99.131  145.288 1.00 84.22  ? 441 VAL E O   1 
ATOM   5386  C  CB  . VAL B 2 388 ? 125.403 99.962  148.391 1.00 70.57  ? 441 VAL E CB  1 
ATOM   5387  C  CG1 . VAL B 2 388 ? 124.245 100.167 147.435 1.00 65.24  ? 441 VAL E CG1 1 
ATOM   5388  C  CG2 . VAL B 2 388 ? 124.946 99.193  149.612 1.00 69.62  ? 441 VAL E CG2 1 
ATOM   5389  N  N   . TYR B 2 389 ? 127.459 100.903 146.185 1.00 80.15  ? 442 TYR E N   1 
ATOM   5390  C  CA  . TYR B 2 389 ? 127.680 101.529 144.884 1.00 75.14  ? 442 TYR E CA  1 
ATOM   5391  C  C   . TYR B 2 389 ? 128.553 100.658 143.987 1.00 76.09  ? 442 TYR E C   1 
ATOM   5392  O  O   . TYR B 2 389 ? 128.200 100.379 142.833 1.00 78.09  ? 442 TYR E O   1 
ATOM   5393  C  CB  . TYR B 2 389 ? 128.311 102.905 145.091 1.00 73.79  ? 442 TYR E CB  1 
ATOM   5394  C  CG  . TYR B 2 389 ? 128.669 103.654 143.834 1.00 72.88  ? 442 TYR E CG  1 
ATOM   5395  C  CD1 . TYR B 2 389 ? 127.765 104.517 143.238 1.00 71.54  ? 442 TYR E CD1 1 
ATOM   5396  C  CD2 . TYR B 2 389 ? 129.923 103.524 143.262 1.00 73.29  ? 442 TYR E CD2 1 
ATOM   5397  C  CE1 . TYR B 2 389 ? 128.094 105.214 142.099 1.00 72.97  ? 442 TYR E CE1 1 
ATOM   5398  C  CE2 . TYR B 2 389 ? 130.260 104.213 142.123 1.00 72.55  ? 442 TYR E CE2 1 
ATOM   5399  C  CZ  . TYR B 2 389 ? 129.343 105.058 141.546 1.00 73.29  ? 442 TYR E CZ  1 
ATOM   5400  O  OH  . TYR B 2 389 ? 129.683 105.745 140.410 1.00 73.56  ? 442 TYR E OH  1 
ATOM   5401  N  N   . TRP B 2 390 ? 129.701 100.220 144.501 1.00 77.37  ? 443 TRP E N   1 
ATOM   5402  C  CA  . TRP B 2 390 ? 130.639 99.453  143.697 1.00 75.90  ? 443 TRP E CA  1 
ATOM   5403  C  C   . TRP B 2 390 ? 130.191 98.020  143.464 1.00 77.47  ? 443 TRP E C   1 
ATOM   5404  O  O   . TRP B 2 390 ? 130.780 97.342  142.619 1.00 83.00  ? 443 TRP E O   1 
ATOM   5405  C  CB  . TRP B 2 390 ? 132.024 99.453  144.342 1.00 77.33  ? 443 TRP E CB  1 
ATOM   5406  C  CG  . TRP B 2 390 ? 132.733 100.770 144.265 1.00 82.56  ? 443 TRP E CG  1 
ATOM   5407  C  CD1 . TRP B 2 390 ? 133.075 101.577 145.308 1.00 82.22  ? 443 TRP E CD1 1 
ATOM   5408  C  CD2 . TRP B 2 390 ? 133.194 101.430 143.081 1.00 85.20  ? 443 TRP E CD2 1 
ATOM   5409  N  NE1 . TRP B 2 390 ? 133.721 102.696 144.850 1.00 83.35  ? 443 TRP E NE1 1 
ATOM   5410  C  CE2 . TRP B 2 390 ? 133.806 102.631 143.484 1.00 87.29  ? 443 TRP E CE2 1 
ATOM   5411  C  CE3 . TRP B 2 390 ? 133.147 101.122 141.719 1.00 83.09  ? 443 TRP E CE3 1 
ATOM   5412  C  CZ2 . TRP B 2 390 ? 134.365 103.525 142.576 1.00 84.03  ? 443 TRP E CZ2 1 
ATOM   5413  C  CZ3 . TRP B 2 390 ? 133.705 102.011 140.819 1.00 83.25  ? 443 TRP E CZ3 1 
ATOM   5414  C  CH2 . TRP B 2 390 ? 134.304 103.197 141.251 1.00 79.17  ? 443 TRP E CH2 1 
ATOM   5415  N  N   . LEU B 2 391 ? 129.186 97.534  144.187 1.00 80.60  ? 444 LEU E N   1 
ATOM   5416  C  CA  . LEU B 2 391 ? 128.572 96.274  143.800 1.00 83.57  ? 444 LEU E CA  1 
ATOM   5417  C  C   . LEU B 2 391 ? 127.471 96.467  142.771 1.00 85.35  ? 444 LEU E C   1 
ATOM   5418  O  O   . LEU B 2 391 ? 127.283 95.603  141.907 1.00 90.92  ? 444 LEU E O   1 
ATOM   5419  C  CB  . LEU B 2 391 ? 128.006 95.551  145.023 1.00 79.21  ? 444 LEU E CB  1 
ATOM   5420  C  CG  . LEU B 2 391 ? 129.035 94.929  145.965 1.00 79.79  ? 444 LEU E CG  1 
ATOM   5421  C  CD1 . LEU B 2 391 ? 128.342 94.142  147.056 1.00 77.84  ? 444 LEU E CD1 1 
ATOM   5422  C  CD2 . LEU B 2 391 ? 130.005 94.054  145.200 1.00 71.59  ? 444 LEU E CD2 1 
ATOM   5423  N  N   . TYR B 2 392 ? 126.747 97.585  142.833 1.00 82.54  ? 445 TYR E N   1 
ATOM   5424  C  CA  . TYR B 2 392 ? 125.683 97.821  141.866 1.00 81.41  ? 445 TYR E CA  1 
ATOM   5425  C  C   . TYR B 2 392 ? 126.249 98.100  140.481 1.00 85.54  ? 445 TYR E C   1 
ATOM   5426  O  O   . TYR B 2 392 ? 125.784 97.534  139.486 1.00 85.27  ? 445 TYR E O   1 
ATOM   5427  C  CB  . TYR B 2 392 ? 124.802 98.976  142.333 1.00 80.15  ? 445 TYR E CB  1 
ATOM   5428  C  CG  . TYR B 2 392 ? 123.654 99.290  141.405 1.00 85.20  ? 445 TYR E CG  1 
ATOM   5429  C  CD1 . TYR B 2 392 ? 123.801 100.202 140.370 1.00 88.56  ? 445 TYR E CD1 1 
ATOM   5430  C  CD2 . TYR B 2 392 ? 122.420 98.682  141.571 1.00 87.09  ? 445 TYR E CD2 1 
ATOM   5431  C  CE1 . TYR B 2 392 ? 122.755 100.492 139.522 1.00 90.58  ? 445 TYR E CE1 1 
ATOM   5432  C  CE2 . TYR B 2 392 ? 121.367 98.969  140.729 1.00 95.15  ? 445 TYR E CE2 1 
ATOM   5433  C  CZ  . TYR B 2 392 ? 121.541 99.875  139.706 1.00 97.73  ? 445 TYR E CZ  1 
ATOM   5434  O  OH  . TYR B 2 392 ? 120.498 100.168 138.861 1.00 104.23 ? 445 TYR E OH  1 
ATOM   5435  N  N   . TYR B 2 393 ? 127.253 98.970  140.391 1.00 87.88  ? 446 TYR E N   1 
ATOM   5436  C  CA  . TYR B 2 393 ? 127.754 99.407  139.094 1.00 84.53  ? 446 TYR E CA  1 
ATOM   5437  C  C   . TYR B 2 393 ? 128.950 98.608  138.598 1.00 83.37  ? 446 TYR E C   1 
ATOM   5438  O  O   . TYR B 2 393 ? 129.498 98.939  137.544 1.00 81.73  ? 446 TYR E O   1 
ATOM   5439  C  CB  . TYR B 2 393 ? 128.105 100.896 139.136 1.00 74.74  ? 446 TYR E CB  1 
ATOM   5440  C  CG  . TYR B 2 393 ? 126.883 101.775 139.116 1.00 75.23  ? 446 TYR E CG  1 
ATOM   5441  C  CD1 . TYR B 2 393 ? 126.103 101.876 137.977 1.00 79.34  ? 446 TYR E CD1 1 
ATOM   5442  C  CD2 . TYR B 2 393 ? 126.503 102.498 140.234 1.00 77.19  ? 446 TYR E CD2 1 
ATOM   5443  C  CE1 . TYR B 2 393 ? 124.980 102.675 137.952 1.00 82.03  ? 446 TYR E CE1 1 
ATOM   5444  C  CE2 . TYR B 2 393 ? 125.381 103.300 140.217 1.00 81.12  ? 446 TYR E CE2 1 
ATOM   5445  C  CZ  . TYR B 2 393 ? 124.624 103.383 139.074 1.00 81.75  ? 446 TYR E CZ  1 
ATOM   5446  O  OH  . TYR B 2 393 ? 123.508 104.180 139.051 1.00 76.57  ? 446 TYR E OH  1 
ATOM   5447  N  N   . VAL B 2 394 ? 129.369 97.576  139.321 1.00 84.89  ? 447 VAL E N   1 
ATOM   5448  C  CA  . VAL B 2 394 ? 130.455 96.715  138.865 1.00 90.25  ? 447 VAL E CA  1 
ATOM   5449  C  C   . VAL B 2 394 ? 130.092 95.253  139.106 1.00 92.56  ? 447 VAL E C   1 
ATOM   5450  O  O   . VAL B 2 394 ? 130.160 94.427  138.195 1.00 96.59  ? 447 VAL E O   1 
ATOM   5451  C  CB  . VAL B 2 394 ? 131.790 97.057  139.557 1.00 89.95  ? 447 VAL E CB  1 
ATOM   5452  C  CG1 . VAL B 2 394 ? 132.886 96.131  139.067 1.00 80.98  ? 447 VAL E CG1 1 
ATOM   5453  C  CG2 . VAL B 2 394 ? 132.178 98.510  139.315 1.00 83.58  ? 447 VAL E CG2 1 
ATOM   5454  N  N   . ASN C 2 62  ? 119.897 155.391 74.204  1.00 77.68  ? 8   ASN B N   1 
ATOM   5455  C  CA  . ASN C 2 62  ? 119.748 154.212 73.360  1.00 87.71  ? 8   ASN B CA  1 
ATOM   5456  C  C   . ASN C 2 62  ? 120.478 153.033 73.979  1.00 89.35  ? 8   ASN B C   1 
ATOM   5457  O  O   . ASN C 2 62  ? 121.688 153.086 74.177  1.00 91.36  ? 8   ASN B O   1 
ATOM   5458  C  CB  . ASN C 2 62  ? 120.273 154.488 71.951  1.00 88.96  ? 8   ASN B CB  1 
ATOM   5459  C  CG  . ASN C 2 62  ? 120.079 153.313 71.017  1.00 89.23  ? 8   ASN B CG  1 
ATOM   5460  O  OD1 . ASN C 2 62  ? 119.289 152.411 71.288  1.00 91.31  ? 8   ASN B OD1 1 
ATOM   5461  N  ND2 . ASN C 2 62  ? 120.798 153.323 69.902  1.00 85.50  ? 8   ASN B ND2 1 
ATOM   5462  N  N   . MET C 2 63  ? 119.734 151.971 74.291  1.00 88.73  ? 9   MET B N   1 
ATOM   5463  C  CA  . MET C 2 63  ? 120.323 150.812 74.951  1.00 85.97  ? 9   MET B CA  1 
ATOM   5464  C  C   . MET C 2 63  ? 121.117 149.934 73.993  1.00 87.73  ? 9   MET B C   1 
ATOM   5465  O  O   . MET C 2 63  ? 122.127 149.351 74.395  1.00 85.38  ? 9   MET B O   1 
ATOM   5466  C  CB  . MET C 2 63  ? 119.234 149.987 75.636  1.00 86.89  ? 9   MET B CB  1 
ATOM   5467  C  CG  . MET C 2 63  ? 118.469 150.748 76.706  1.00 92.97  ? 9   MET B CG  1 
ATOM   5468  S  SD  . MET C 2 63  ? 117.259 149.737 77.575  1.00 110.23 ? 9   MET B SD  1 
ATOM   5469  C  CE  . MET C 2 63  ? 118.322 148.659 78.523  1.00 78.57  ? 9   MET B CE  1 
ATOM   5470  N  N   . SER C 2 64  ? 120.679 149.813 72.737  1.00 90.97  ? 10  SER B N   1 
ATOM   5471  C  CA  . SER C 2 64  ? 121.396 148.967 71.786  1.00 90.78  ? 10  SER B CA  1 
ATOM   5472  C  C   . SER C 2 64  ? 122.776 149.531 71.470  1.00 89.79  ? 10  SER B C   1 
ATOM   5473  O  O   . SER C 2 64  ? 123.747 148.776 71.335  1.00 89.90  ? 10  SER B O   1 
ATOM   5474  C  CB  . SER C 2 64  ? 120.573 148.801 70.511  1.00 89.97  ? 10  SER B CB  1 
ATOM   5475  O  OG  . SER C 2 64  ? 120.253 150.060 69.948  1.00 92.73  ? 10  SER B OG  1 
ATOM   5476  N  N   . PHE C 2 65  ? 122.882 150.855 71.347  1.00 86.73  ? 11  PHE B N   1 
ATOM   5477  C  CA  . PHE C 2 65  ? 124.181 151.479 71.120  1.00 85.59  ? 11  PHE B CA  1 
ATOM   5478  C  C   . PHE C 2 65  ? 125.127 151.227 72.288  1.00 84.15  ? 11  PHE B C   1 
ATOM   5479  O  O   . PHE C 2 65  ? 126.305 150.906 72.088  1.00 84.06  ? 11  PHE B O   1 
ATOM   5480  C  CB  . PHE C 2 65  ? 123.994 152.977 70.888  1.00 85.38  ? 11  PHE B CB  1 
ATOM   5481  C  CG  . PHE C 2 65  ? 125.275 153.748 70.830  1.00 87.88  ? 11  PHE B CG  1 
ATOM   5482  C  CD1 . PHE C 2 65  ? 126.046 153.745 69.684  1.00 90.23  ? 11  PHE B CD1 1 
ATOM   5483  C  CD2 . PHE C 2 65  ? 125.700 154.490 71.916  1.00 85.01  ? 11  PHE B CD2 1 
ATOM   5484  C  CE1 . PHE C 2 65  ? 127.224 154.459 69.624  1.00 89.23  ? 11  PHE B CE1 1 
ATOM   5485  C  CE2 . PHE C 2 65  ? 126.875 155.206 71.862  1.00 89.21  ? 11  PHE B CE2 1 
ATOM   5486  C  CZ  . PHE C 2 65  ? 127.639 155.190 70.714  1.00 89.37  ? 11  PHE B CZ  1 
ATOM   5487  N  N   . VAL C 2 66  ? 124.628 151.354 73.516  1.00 79.83  ? 12  VAL B N   1 
ATOM   5488  C  CA  . VAL C 2 66  ? 125.470 151.106 74.680  1.00 79.17  ? 12  VAL B CA  1 
ATOM   5489  C  C   . VAL C 2 66  ? 125.861 149.636 74.753  1.00 80.15  ? 12  VAL B C   1 
ATOM   5490  O  O   . VAL C 2 66  ? 126.987 149.297 75.135  1.00 80.80  ? 12  VAL B O   1 
ATOM   5491  C  CB  . VAL C 2 66  ? 124.758 151.576 75.961  1.00 78.07  ? 12  VAL B CB  1 
ATOM   5492  C  CG1 . VAL C 2 66  ? 125.596 151.261 77.180  1.00 74.79  ? 12  VAL B CG1 1 
ATOM   5493  C  CG2 . VAL C 2 66  ? 124.471 153.063 75.884  1.00 73.30  ? 12  VAL B CG2 1 
ATOM   5494  N  N   . LYS C 2 67  ? 124.943 148.738 74.389  1.00 78.74  ? 13  LYS B N   1 
ATOM   5495  C  CA  . LYS C 2 67  ? 125.275 147.319 74.393  1.00 78.45  ? 13  LYS B CA  1 
ATOM   5496  C  C   . LYS C 2 67  ? 126.370 147.007 73.383  1.00 78.15  ? 13  LYS B C   1 
ATOM   5497  O  O   . LYS C 2 67  ? 127.296 146.247 73.681  1.00 76.62  ? 13  LYS B O   1 
ATOM   5498  C  CB  . LYS C 2 67  ? 124.037 146.473 74.106  1.00 80.46  ? 13  LYS B CB  1 
ATOM   5499  C  CG  . LYS C 2 67  ? 124.337 144.986 74.066  1.00 77.55  ? 13  LYS B CG  1 
ATOM   5500  C  CD  . LYS C 2 67  ? 123.158 144.166 73.588  1.00 75.59  ? 13  LYS B CD  1 
ATOM   5501  C  CE  . LYS C 2 67  ? 123.545 142.705 73.476  1.00 76.94  ? 13  LYS B CE  1 
ATOM   5502  N  NZ  . LYS C 2 67  ? 122.379 141.845 73.150  1.00 83.44  ? 13  LYS B NZ  1 
ATOM   5503  N  N   . GLU C 2 68  ? 126.287 147.585 72.183  1.00 78.17  ? 14  GLU B N   1 
ATOM   5504  C  CA  . GLU C 2 68  ? 127.334 147.331 71.199  1.00 78.01  ? 14  GLU B CA  1 
ATOM   5505  C  C   . GLU C 2 68  ? 128.654 147.964 71.621  1.00 81.52  ? 14  GLU B C   1 
ATOM   5506  O  O   . GLU C 2 68  ? 129.720 147.396 71.362  1.00 79.52  ? 14  GLU B O   1 
ATOM   5507  C  CB  . GLU C 2 68  ? 126.901 147.813 69.810  1.00 82.97  ? 14  GLU B CB  1 
ATOM   5508  C  CG  . GLU C 2 68  ? 127.078 149.294 69.536  1.00 86.29  ? 14  GLU B CG  1 
ATOM   5509  C  CD  . GLU C 2 68  ? 126.649 149.689 68.131  1.00 98.45  ? 14  GLU B CD  1 
ATOM   5510  O  OE1 . GLU C 2 68  ? 126.369 148.788 67.313  1.00 106.05 ? 14  GLU B OE1 1 
ATOM   5511  O  OE2 . GLU C 2 68  ? 126.587 150.904 67.846  1.00 98.89  ? 14  GLU B OE2 1 
ATOM   5512  N  N   . THR C 2 69  ? 128.606 149.112 72.303  1.00 83.37  ? 15  THR B N   1 
ATOM   5513  C  CA  . THR C 2 69  ? 129.830 149.711 72.827  1.00 77.81  ? 15  THR B CA  1 
ATOM   5514  C  C   . THR C 2 69  ? 130.487 148.818 73.873  1.00 73.84  ? 15  THR B C   1 
ATOM   5515  O  O   . THR C 2 69  ? 131.705 148.604 73.841  1.00 73.67  ? 15  THR B O   1 
ATOM   5516  C  CB  . THR C 2 69  ? 129.522 151.085 73.416  1.00 73.67  ? 15  THR B CB  1 
ATOM   5517  O  OG1 . THR C 2 69  ? 128.953 151.920 72.403  1.00 75.61  ? 15  THR B OG1 1 
ATOM   5518  C  CG2 . THR C 2 69  ? 130.784 151.733 73.946  1.00 71.70  ? 15  THR B CG2 1 
ATOM   5519  N  N   . VAL C 2 70  ? 129.700 148.278 74.805  1.00 71.53  ? 16  VAL B N   1 
ATOM   5520  C  CA  . VAL C 2 70  ? 130.267 147.409 75.834  1.00 71.95  ? 16  VAL B CA  1 
ATOM   5521  C  C   . VAL C 2 70  ? 130.769 146.107 75.220  1.00 72.95  ? 16  VAL B C   1 
ATOM   5522  O  O   . VAL C 2 70  ? 131.803 145.565 75.635  1.00 71.44  ? 16  VAL B O   1 
ATOM   5523  C  CB  . VAL C 2 70  ? 129.243 147.158 76.955  1.00 71.01  ? 16  VAL B CB  1 
ATOM   5524  C  CG1 . VAL C 2 70  ? 129.808 146.194 77.982  1.00 67.90  ? 16  VAL B CG1 1 
ATOM   5525  C  CG2 . VAL C 2 70  ? 128.864 148.465 77.625  1.00 64.16  ? 16  VAL B CG2 1 
ATOM   5526  N  N   . ASP C 2 71  ? 130.053 145.583 74.222  1.00 73.93  ? 17  ASP B N   1 
ATOM   5527  C  CA  . ASP C 2 71  ? 130.525 144.396 73.520  1.00 74.82  ? 17  ASP B CA  1 
ATOM   5528  C  C   . ASP C 2 71  ? 131.858 144.658 72.836  1.00 72.63  ? 17  ASP B C   1 
ATOM   5529  O  O   . ASP C 2 71  ? 132.753 143.806 72.856  1.00 72.40  ? 17  ASP B O   1 
ATOM   5530  C  CB  . ASP C 2 71  ? 129.489 143.938 72.497  1.00 79.94  ? 17  ASP B CB  1 
ATOM   5531  C  CG  . ASP C 2 71  ? 128.304 143.248 73.133  1.00 86.84  ? 17  ASP B CG  1 
ATOM   5532  O  OD1 . ASP C 2 71  ? 128.192 143.269 74.376  1.00 87.51  ? 17  ASP B OD1 1 
ATOM   5533  O  OD2 . ASP C 2 71  ? 127.487 142.674 72.384  1.00 85.89  ? 17  ASP B OD2 1 
ATOM   5534  N  N   . LYS C 2 72  ? 132.006 145.828 72.215  1.00 72.52  ? 18  LYS B N   1 
ATOM   5535  C  CA  . LYS C 2 72  ? 133.286 146.191 71.622  1.00 74.55  ? 18  LYS B CA  1 
ATOM   5536  C  C   . LYS C 2 72  ? 134.369 146.291 72.686  1.00 72.52  ? 18  LYS B C   1 
ATOM   5537  O  O   . LYS C 2 72  ? 135.515 145.892 72.455  1.00 72.36  ? 18  LYS B O   1 
ATOM   5538  C  CB  . LYS C 2 72  ? 133.151 147.509 70.863  1.00 79.15  ? 18  LYS B CB  1 
ATOM   5539  C  CG  . LYS C 2 72  ? 134.419 147.988 70.188  1.00 80.17  ? 18  LYS B CG  1 
ATOM   5540  C  CD  . LYS C 2 72  ? 134.189 149.335 69.525  1.00 86.02  ? 18  LYS B CD  1 
ATOM   5541  C  CE  . LYS C 2 72  ? 135.453 149.865 68.874  1.00 93.19  ? 18  LYS B CE  1 
ATOM   5542  N  NZ  . LYS C 2 72  ? 135.232 151.209 68.267  1.00 95.75  ? 18  LYS B NZ  1 
ATOM   5543  N  N   . LEU C 2 73  ? 134.023 146.824 73.860  1.00 70.17  ? 19  LEU B N   1 
ATOM   5544  C  CA  . LEU C 2 73  ? 134.995 146.907 74.946  1.00 66.70  ? 19  LEU B CA  1 
ATOM   5545  C  C   . LEU C 2 73  ? 135.484 145.526 75.361  1.00 66.35  ? 19  LEU B C   1 
ATOM   5546  O  O   . LEU C 2 73  ? 136.686 145.318 75.553  1.00 64.31  ? 19  LEU B O   1 
ATOM   5547  C  CB  . LEU C 2 73  ? 134.390 147.633 76.145  1.00 62.23  ? 19  LEU B CB  1 
ATOM   5548  C  CG  . LEU C 2 73  ? 134.179 149.134 75.979  1.00 62.58  ? 19  LEU B CG  1 
ATOM   5549  C  CD1 . LEU C 2 73  ? 133.575 149.718 77.234  1.00 59.71  ? 19  LEU B CD1 1 
ATOM   5550  C  CD2 . LEU C 2 73  ? 135.490 149.810 75.651  1.00 60.83  ? 19  LEU B CD2 1 
ATOM   5551  N  N   . LEU C 2 74  ? 134.576 144.568 75.495  1.00 67.13  ? 20  LEU B N   1 
ATOM   5552  C  CA  . LEU C 2 74  ? 134.966 143.233 75.929  1.00 65.00  ? 20  LEU B CA  1 
ATOM   5553  C  C   . LEU C 2 74  ? 135.341 142.310 74.777  1.00 67.48  ? 20  LEU B C   1 
ATOM   5554  O  O   . LEU C 2 74  ? 135.633 141.137 75.018  1.00 64.80  ? 20  LEU B O   1 
ATOM   5555  C  CB  . LEU C 2 74  ? 133.851 142.600 76.758  1.00 65.25  ? 20  LEU B CB  1 
ATOM   5556  C  CG  . LEU C 2 74  ? 133.664 143.259 78.121  1.00 63.39  ? 20  LEU B CG  1 
ATOM   5557  C  CD1 . LEU C 2 74  ? 132.557 142.579 78.891  1.00 61.28  ? 20  LEU B CD1 1 
ATOM   5558  C  CD2 . LEU C 2 74  ? 134.956 143.220 78.904  1.00 57.38  ? 20  LEU B CD2 1 
ATOM   5559  N  N   . LYS C 2 75  ? 135.344 142.803 73.543  1.00 71.33  ? 21  LYS B N   1 
ATOM   5560  C  CA  . LYS C 2 75  ? 135.754 142.000 72.399  1.00 69.51  ? 21  LYS B CA  1 
ATOM   5561  C  C   . LYS C 2 75  ? 137.275 141.940 72.340  1.00 69.71  ? 21  LYS B C   1 
ATOM   5562  O  O   . LYS C 2 75  ? 137.938 142.977 72.243  1.00 70.76  ? 21  LYS B O   1 
ATOM   5563  C  CB  . LYS C 2 75  ? 135.192 142.588 71.108  1.00 69.02  ? 21  LYS B CB  1 
ATOM   5564  C  CG  . LYS C 2 75  ? 135.793 142.006 69.844  1.00 70.02  ? 21  LYS B CG  1 
ATOM   5565  C  CD  . LYS C 2 75  ? 135.428 140.545 69.679  1.00 73.29  ? 21  LYS B CD  1 
ATOM   5566  C  CE  . LYS C 2 75  ? 133.935 140.360 69.492  1.00 74.30  ? 21  LYS B CE  1 
ATOM   5567  N  NZ  . LYS C 2 75  ? 133.595 138.922 69.332  1.00 81.62  ? 21  LYS B NZ  1 
ATOM   5568  N  N   . GLY C 2 76  ? 137.827 140.730 72.385  1.00 66.50  ? 22  GLY B N   1 
ATOM   5569  C  CA  . GLY C 2 76  ? 139.268 140.584 72.360  1.00 65.63  ? 22  GLY B CA  1 
ATOM   5570  C  C   . GLY C 2 76  ? 139.962 141.017 73.628  1.00 65.68  ? 22  GLY B C   1 
ATOM   5571  O  O   . GLY C 2 76  ? 141.145 141.360 73.590  1.00 70.17  ? 22  GLY B O   1 
ATOM   5572  N  N   . TYR C 2 77  ? 139.254 141.017 74.751  1.00 61.80  ? 23  TYR B N   1 
ATOM   5573  C  CA  . TYR C 2 77  ? 139.808 141.420 76.035  1.00 54.72  ? 23  TYR B CA  1 
ATOM   5574  C  C   . TYR C 2 77  ? 140.405 140.199 76.719  1.00 55.16  ? 23  TYR B C   1 
ATOM   5575  O  O   . TYR C 2 77  ? 139.689 139.240 77.019  1.00 57.40  ? 23  TYR B O   1 
ATOM   5576  C  CB  . TYR C 2 77  ? 138.719 142.054 76.897  1.00 52.52  ? 23  TYR B CB  1 
ATOM   5577  C  CG  . TYR C 2 77  ? 139.178 142.566 78.236  1.00 46.44  ? 23  TYR B CG  1 
ATOM   5578  C  CD1 . TYR C 2 77  ? 139.701 143.838 78.368  1.00 45.99  ? 23  TYR B CD1 1 
ATOM   5579  C  CD2 . TYR C 2 77  ? 139.065 141.786 79.373  1.00 44.94  ? 23  TYR B CD2 1 
ATOM   5580  C  CE1 . TYR C 2 77  ? 140.112 144.310 79.589  1.00 44.03  ? 23  TYR B CE1 1 
ATOM   5581  C  CE2 . TYR C 2 77  ? 139.476 142.252 80.596  1.00 42.11  ? 23  TYR B CE2 1 
ATOM   5582  C  CZ  . TYR C 2 77  ? 139.998 143.514 80.696  1.00 42.60  ? 23  TYR B CZ  1 
ATOM   5583  O  OH  . TYR C 2 77  ? 140.406 143.987 81.915  1.00 45.45  ? 23  TYR B OH  1 
ATOM   5584  N  N   . ASP C 2 78  ? 141.715 140.226 76.945  1.00 53.71  ? 24  ASP B N   1 
ATOM   5585  C  CA  . ASP C 2 78  ? 142.417 139.113 77.578  1.00 51.67  ? 24  ASP B CA  1 
ATOM   5586  C  C   . ASP C 2 78  ? 142.446 139.367 79.079  1.00 50.43  ? 24  ASP B C   1 
ATOM   5587  O  O   . ASP C 2 78  ? 143.238 140.172 79.570  1.00 48.68  ? 24  ASP B O   1 
ATOM   5588  C  CB  . ASP C 2 78  ? 143.818 138.963 77.002  1.00 48.92  ? 24  ASP B CB  1 
ATOM   5589  C  CG  . ASP C 2 78  ? 144.439 137.631 77.337  1.00 52.16  ? 24  ASP B CG  1 
ATOM   5590  O  OD1 . ASP C 2 78  ? 143.832 136.870 78.114  1.00 52.09  ? 24  ASP B OD1 1 
ATOM   5591  O  OD2 . ASP C 2 78  ? 145.532 137.340 76.819  1.00 55.96  ? 24  ASP B OD2 1 
ATOM   5592  N  N   . ILE C 2 79  ? 141.571 138.674 79.809  1.00 49.23  ? 25  ILE B N   1 
ATOM   5593  C  CA  . ILE C 2 79  ? 141.463 138.871 81.247  1.00 48.33  ? 25  ILE B CA  1 
ATOM   5594  C  C   . ILE C 2 79  ? 142.703 138.390 81.984  1.00 46.91  ? 25  ILE B C   1 
ATOM   5595  O  O   . ILE C 2 79  ? 142.990 138.872 83.083  1.00 48.54  ? 25  ILE B O   1 
ATOM   5596  C  CB  . ILE C 2 79  ? 140.199 138.163 81.767  1.00 49.59  ? 25  ILE B CB  1 
ATOM   5597  C  CG1 . ILE C 2 79  ? 139.984 138.444 83.248  1.00 41.71  ? 25  ILE B CG1 1 
ATOM   5598  C  CG2 . ILE C 2 79  ? 140.293 136.675 81.539  1.00 49.71  ? 25  ILE B CG2 1 
ATOM   5599  C  CD1 . ILE C 2 79  ? 138.865 137.643 83.834  1.00 42.66  ? 25  ILE B CD1 1 
ATOM   5600  N  N   . ARG C 2 80  ? 143.455 137.453 81.404  1.00 45.94  ? 26  ARG B N   1 
ATOM   5601  C  CA  . ARG C 2 80  ? 144.605 136.876 82.088  1.00 45.46  ? 26  ARG B CA  1 
ATOM   5602  C  C   . ARG C 2 80  ? 145.754 137.860 82.246  1.00 47.22  ? 26  ARG B C   1 
ATOM   5603  O  O   . ARG C 2 80  ? 146.638 137.628 83.075  1.00 49.77  ? 26  ARG B O   1 
ATOM   5604  C  CB  . ARG C 2 80  ? 145.093 135.639 81.336  1.00 45.67  ? 26  ARG B CB  1 
ATOM   5605  C  CG  . ARG C 2 80  ? 144.032 134.586 81.110  1.00 48.00  ? 26  ARG B CG  1 
ATOM   5606  C  CD  . ARG C 2 80  ? 144.485 133.552 80.099  1.00 49.30  ? 26  ARG B CD  1 
ATOM   5607  N  NE  . ARG C 2 80  ? 144.664 134.131 78.773  1.00 52.59  ? 26  ARG B NE  1 
ATOM   5608  C  CZ  . ARG C 2 80  ? 144.914 133.431 77.674  1.00 56.46  ? 26  ARG B CZ  1 
ATOM   5609  N  NH1 . ARG C 2 80  ? 145.014 132.115 77.701  1.00 59.23  ? 26  ARG B NH1 1 
ATOM   5610  N  NH2 . ARG C 2 80  ? 145.067 134.070 76.519  1.00 55.58  ? 26  ARG B NH2 1 
ATOM   5611  N  N   . LEU C 2 81  ? 145.763 138.950 81.488  1.00 46.61  ? 27  LEU B N   1 
ATOM   5612  C  CA  . LEU C 2 81  ? 146.850 139.916 81.510  1.00 42.56  ? 27  LEU B CA  1 
ATOM   5613  C  C   . LEU C 2 81  ? 146.412 141.186 82.223  1.00 45.48  ? 27  LEU B C   1 
ATOM   5614  O  O   . LEU C 2 81  ? 145.314 141.693 81.989  1.00 48.76  ? 27  LEU B O   1 
ATOM   5615  C  CB  . LEU C 2 81  ? 147.307 140.258 80.092  1.00 41.30  ? 27  LEU B CB  1 
ATOM   5616  C  CG  . LEU C 2 81  ? 147.596 139.101 79.144  1.00 41.44  ? 27  LEU B CG  1 
ATOM   5617  C  CD1 . LEU C 2 81  ? 147.848 139.637 77.760  1.00 42.26  ? 27  LEU B CD1 1 
ATOM   5618  C  CD2 . LEU C 2 81  ? 148.784 138.304 79.618  1.00 42.78  ? 27  LEU B CD2 1 
ATOM   5619  N  N   . ARG C 2 82  ? 147.283 141.698 83.085  1.00 45.20  ? 28  ARG B N   1 
ATOM   5620  C  CA  . ARG C 2 82  ? 147.021 142.940 83.787  1.00 45.15  ? 28  ARG B CA  1 
ATOM   5621  C  C   . ARG C 2 82  ? 147.116 144.126 82.830  1.00 47.84  ? 28  ARG B C   1 
ATOM   5622  O  O   . ARG C 2 82  ? 147.657 144.005 81.731  1.00 48.42  ? 28  ARG B O   1 
ATOM   5623  C  CB  . ARG C 2 82  ? 148.014 143.119 84.927  1.00 42.93  ? 28  ARG B CB  1 
ATOM   5624  C  CG  . ARG C 2 82  ? 149.412 143.436 84.462  1.00 45.52  ? 28  ARG B CG  1 
ATOM   5625  C  CD  . ARG C 2 82  ? 150.247 143.971 85.593  1.00 44.93  ? 28  ARG B CD  1 
ATOM   5626  N  NE  . ARG C 2 82  ? 151.640 144.134 85.203  1.00 50.66  ? 28  ARG B NE  1 
ATOM   5627  C  CZ  . ARG C 2 82  ? 152.138 145.210 84.610  1.00 49.49  ? 28  ARG B CZ  1 
ATOM   5628  N  NH1 . ARG C 2 82  ? 151.380 146.252 84.314  1.00 46.17  ? 28  ARG B NH1 1 
ATOM   5629  N  NH2 . ARG C 2 82  ? 153.432 145.244 84.315  1.00 48.30  ? 28  ARG B NH2 1 
ATOM   5630  N  N   . PRO C 2 83  ? 146.569 145.277 83.215  1.00 46.38  ? 29  PRO B N   1 
ATOM   5631  C  CA  . PRO C 2 83  ? 146.757 146.482 82.401  1.00 52.09  ? 29  PRO B CA  1 
ATOM   5632  C  C   . PRO C 2 83  ? 148.231 146.815 82.239  1.00 54.70  ? 29  PRO B C   1 
ATOM   5633  O  O   . PRO C 2 83  ? 149.029 146.648 83.162  1.00 56.94  ? 29  PRO B O   1 
ATOM   5634  C  CB  . PRO C 2 83  ? 146.024 147.563 83.199  1.00 50.64  ? 29  PRO B CB  1 
ATOM   5635  C  CG  . PRO C 2 83  ? 145.028 146.826 83.996  1.00 42.93  ? 29  PRO B CG  1 
ATOM   5636  C  CD  . PRO C 2 83  ? 145.637 145.509 84.327  1.00 39.20  ? 29  PRO B CD  1 
ATOM   5637  N  N   . ASP C 2 84  ? 148.584 147.296 81.046  1.00 53.86  ? 30  ASP B N   1 
ATOM   5638  C  CA  . ASP C 2 84  ? 149.963 147.647 80.706  1.00 54.80  ? 30  ASP B CA  1 
ATOM   5639  C  C   . ASP C 2 84  ? 150.907 146.470 80.927  1.00 54.91  ? 30  ASP B C   1 
ATOM   5640  O  O   . ASP C 2 84  ? 152.020 146.635 81.424  1.00 57.13  ? 30  ASP B O   1 
ATOM   5641  C  CB  . ASP C 2 84  ? 150.439 148.862 81.503  1.00 58.32  ? 30  ASP B CB  1 
ATOM   5642  C  CG  . ASP C 2 84  ? 149.461 150.008 81.460  1.00 68.77  ? 30  ASP B CG  1 
ATOM   5643  O  OD1 . ASP C 2 84  ? 148.485 149.932 80.686  1.00 73.46  ? 30  ASP B OD1 1 
ATOM   5644  O  OD2 . ASP C 2 84  ? 149.666 150.984 82.209  1.00 72.22  ? 30  ASP B OD2 1 
ATOM   5645  N  N   . PHE C 2 85  ? 150.458 145.272 80.568  1.00 51.75  ? 31  PHE B N   1 
ATOM   5646  C  CA  . PHE C 2 85  ? 151.268 144.080 80.780  1.00 47.98  ? 31  PHE B CA  1 
ATOM   5647  C  C   . PHE C 2 85  ? 152.583 144.188 80.023  1.00 56.05  ? 31  PHE B C   1 
ATOM   5648  O  O   . PHE C 2 85  ? 152.610 144.557 78.846  1.00 62.20  ? 31  PHE B O   1 
ATOM   5649  C  CB  . PHE C 2 85  ? 150.496 142.843 80.336  1.00 43.76  ? 31  PHE B CB  1 
ATOM   5650  C  CG  . PHE C 2 85  ? 151.222 141.552 80.573  1.00 45.91  ? 31  PHE B CG  1 
ATOM   5651  C  CD1 . PHE C 2 85  ? 151.246 140.977 81.825  1.00 45.49  ? 31  PHE B CD1 1 
ATOM   5652  C  CD2 . PHE C 2 85  ? 151.854 140.899 79.536  1.00 49.84  ? 31  PHE B CD2 1 
ATOM   5653  C  CE1 . PHE C 2 85  ? 151.898 139.785 82.038  1.00 44.87  ? 31  PHE B CE1 1 
ATOM   5654  C  CE2 . PHE C 2 85  ? 152.510 139.708 79.747  1.00 48.09  ? 31  PHE B CE2 1 
ATOM   5655  C  CZ  . PHE C 2 85  ? 152.531 139.152 80.999  1.00 44.93  ? 31  PHE B CZ  1 
ATOM   5656  N  N   . GLY C 2 86  ? 153.678 143.874 80.706  1.00 52.09  ? 32  GLY B N   1 
ATOM   5657  C  CA  . GLY C 2 86  ? 154.990 144.004 80.116  1.00 52.99  ? 32  GLY B CA  1 
ATOM   5658  C  C   . GLY C 2 86  ? 155.550 145.407 80.096  1.00 60.76  ? 32  GLY B C   1 
ATOM   5659  O  O   . GLY C 2 86  ? 156.617 145.619 79.511  1.00 66.16  ? 32  GLY B O   1 
ATOM   5660  N  N   . GLY C 2 87  ? 154.873 146.371 80.714  1.00 59.70  ? 33  GLY B N   1 
ATOM   5661  C  CA  . GLY C 2 87  ? 155.326 147.740 80.711  1.00 57.45  ? 33  GLY B CA  1 
ATOM   5662  C  C   . GLY C 2 87  ? 155.408 148.331 82.102  1.00 58.28  ? 33  GLY B C   1 
ATOM   5663  O  O   . GLY C 2 87  ? 155.855 147.683 83.051  1.00 61.06  ? 33  GLY B O   1 
ATOM   5664  N  N   . PRO C 2 88  ? 154.989 149.583 82.246  1.00 60.19  ? 34  PRO B N   1 
ATOM   5665  C  CA  . PRO C 2 88  ? 155.026 150.239 83.555  1.00 57.82  ? 34  PRO B CA  1 
ATOM   5666  C  C   . PRO C 2 88  ? 154.009 149.631 84.504  1.00 55.50  ? 34  PRO B C   1 
ATOM   5667  O  O   . PRO C 2 88  ? 153.020 149.028 84.065  1.00 56.68  ? 34  PRO B O   1 
ATOM   5668  C  CB  . PRO C 2 88  ? 154.680 151.697 83.224  1.00 54.05  ? 34  PRO B CB  1 
ATOM   5669  C  CG  . PRO C 2 88  ? 153.869 151.606 81.986  1.00 60.12  ? 34  PRO B CG  1 
ATOM   5670  C  CD  . PRO C 2 88  ? 154.457 150.470 81.200  1.00 60.26  ? 34  PRO B CD  1 
ATOM   5671  N  N   . PRO C 2 89  ? 154.225 149.749 85.810  1.00 53.32  ? 35  PRO B N   1 
ATOM   5672  C  CA  . PRO C 2 89  ? 153.244 149.230 86.767  1.00 53.50  ? 35  PRO B CA  1 
ATOM   5673  C  C   . PRO C 2 89  ? 151.952 150.031 86.756  1.00 55.11  ? 35  PRO B C   1 
ATOM   5674  O  O   . PRO C 2 89  ? 151.915 151.196 86.357  1.00 57.44  ? 35  PRO B O   1 
ATOM   5675  C  CB  . PRO C 2 89  ? 153.962 149.357 88.115  1.00 49.51  ? 35  PRO B CB  1 
ATOM   5676  C  CG  . PRO C 2 89  ? 154.988 150.402 87.897  1.00 52.85  ? 35  PRO B CG  1 
ATOM   5677  C  CD  . PRO C 2 89  ? 155.433 150.252 86.482  1.00 52.54  ? 35  PRO B CD  1 
ATOM   5678  N  N   . VAL C 2 90  ? 150.882 149.379 87.198  1.00 52.74  ? 36  VAL B N   1 
ATOM   5679  C  CA  . VAL C 2 90  ? 149.560 149.984 87.300  1.00 49.17  ? 36  VAL B CA  1 
ATOM   5680  C  C   . VAL C 2 90  ? 149.330 150.396 88.747  1.00 46.07  ? 36  VAL B C   1 
ATOM   5681  O  O   . VAL C 2 90  ? 149.584 149.613 89.668  1.00 46.58  ? 36  VAL B O   1 
ATOM   5682  C  CB  . VAL C 2 90  ? 148.471 149.012 86.811  1.00 43.03  ? 36  VAL B CB  1 
ATOM   5683  C  CG1 . VAL C 2 90  ? 148.761 147.615 87.293  1.00 42.18  ? 36  VAL B CG1 1 
ATOM   5684  C  CG2 . VAL C 2 90  ? 147.112 149.445 87.288  1.00 42.28  ? 36  VAL B CG2 1 
ATOM   5685  N  N   . CYS C 2 91  ? 148.868 151.628 88.952  1.00 43.30  ? 37  CYS B N   1 
ATOM   5686  C  CA  . CYS C 2 91  ? 148.661 152.171 90.288  1.00 43.78  ? 37  CYS B CA  1 
ATOM   5687  C  C   . CYS C 2 91  ? 147.219 151.960 90.726  1.00 41.74  ? 37  CYS B C   1 
ATOM   5688  O  O   . CYS C 2 91  ? 146.290 152.348 90.016  1.00 44.78  ? 37  CYS B O   1 
ATOM   5689  C  CB  . CYS C 2 91  ? 148.997 153.660 90.317  1.00 46.27  ? 37  CYS B CB  1 
ATOM   5690  S  SG  . CYS C 2 91  ? 150.589 154.075 89.589  1.00 79.68  ? 37  CYS B SG  1 
ATOM   5691  N  N   . VAL C 2 92  ? 147.037 151.370 91.905  1.00 35.45  ? 38  VAL B N   1 
ATOM   5692  C  CA  . VAL C 2 92  ? 145.716 151.089 92.455  1.00 33.91  ? 38  VAL B CA  1 
ATOM   5693  C  C   . VAL C 2 92  ? 145.562 151.874 93.750  1.00 35.11  ? 38  VAL B C   1 
ATOM   5694  O  O   . VAL C 2 92  ? 146.347 151.693 94.686  1.00 37.46  ? 38  VAL B O   1 
ATOM   5695  C  CB  . VAL C 2 92  ? 145.509 149.588 92.700  1.00 30.66  ? 38  VAL B CB  1 
ATOM   5696  C  CG1 . VAL C 2 92  ? 144.080 149.308 93.101  1.00 30.55  ? 38  VAL B CG1 1 
ATOM   5697  C  CG2 . VAL C 2 92  ? 145.872 148.799 91.466  1.00 32.17  ? 38  VAL B CG2 1 
ATOM   5698  N  N   . GLY C 2 93  ? 144.546 152.732 93.805  1.00 33.30  ? 39  GLY B N   1 
ATOM   5699  C  CA  . GLY C 2 93  ? 144.264 153.510 94.999  1.00 30.19  ? 39  GLY B CA  1 
ATOM   5700  C  C   . GLY C 2 93  ? 143.188 152.850 95.844  1.00 31.93  ? 39  GLY B C   1 
ATOM   5701  O  O   . GLY C 2 93  ? 142.211 152.324 95.326  1.00 35.84  ? 39  GLY B O   1 
ATOM   5702  N  N   . MET C 2 94  ? 143.378 152.900 97.159  1.00 31.23  ? 40  MET B N   1 
ATOM   5703  C  CA  . MET C 2 94  ? 142.533 152.192 98.108  1.00 29.54  ? 40  MET B CA  1 
ATOM   5704  C  C   . MET C 2 94  ? 141.736 153.179 98.948  1.00 31.97  ? 40  MET B C   1 
ATOM   5705  O  O   . MET C 2 94  ? 142.256 154.225 99.342  1.00 37.93  ? 40  MET B O   1 
ATOM   5706  C  CB  . MET C 2 94  ? 143.369 151.298 99.025  1.00 31.59  ? 40  MET B CB  1 
ATOM   5707  C  CG  . MET C 2 94  ? 143.568 149.882 98.535  1.00 32.40  ? 40  MET B CG  1 
ATOM   5708  S  SD  . MET C 2 94  ? 144.399 149.788 96.954  1.00 45.63  ? 40  MET B SD  1 
ATOM   5709  C  CE  . MET C 2 94  ? 144.675 148.030 96.863  1.00 38.21  ? 40  MET B CE  1 
ATOM   5710  N  N   . ASN C 2 95  ? 140.478 152.840 99.213  1.00 30.21  ? 41  ASN B N   1 
ATOM   5711  C  CA  . ASN C 2 95  ? 139.627 153.541 100.164 1.00 28.37  ? 41  ASN B CA  1 
ATOM   5712  C  C   . ASN C 2 95  ? 138.943 152.510 101.044 1.00 32.31  ? 41  ASN B C   1 
ATOM   5713  O  O   . ASN C 2 95  ? 138.534 151.455 100.562 1.00 34.43  ? 41  ASN B O   1 
ATOM   5714  C  CB  . ASN C 2 95  ? 138.555 154.379 99.470  1.00 31.52  ? 41  ASN B CB  1 
ATOM   5715  C  CG  . ASN C 2 95  ? 139.039 155.742 99.080  1.00 39.13  ? 41  ASN B CG  1 
ATOM   5716  O  OD1 . ASN C 2 95  ? 138.970 156.122 97.917  1.00 45.38  ? 41  ASN B OD1 1 
ATOM   5717  N  ND2 . ASN C 2 95  ? 139.520 156.498 100.048 1.00 39.24  ? 41  ASN B ND2 1 
ATOM   5718  N  N   . ILE C 2 96  ? 138.820 152.808 102.331 1.00 30.33  ? 42  ILE B N   1 
ATOM   5719  C  CA  . ILE C 2 96  ? 138.102 151.946 103.260 1.00 28.33  ? 42  ILE B CA  1 
ATOM   5720  C  C   . ILE C 2 96  ? 137.106 152.798 104.028 1.00 32.75  ? 42  ILE B C   1 
ATOM   5721  O  O   . ILE C 2 96  ? 137.440 153.899 104.474 1.00 36.90  ? 42  ILE B O   1 
ATOM   5722  C  CB  . ILE C 2 96  ? 139.053 151.214 104.221 1.00 29.39  ? 42  ILE B CB  1 
ATOM   5723  C  CG1 . ILE C 2 96  ? 140.095 150.421 103.445 1.00 29.71  ? 42  ILE B CG1 1 
ATOM   5724  C  CG2 . ILE C 2 96  ? 138.280 150.270 105.115 1.00 29.03  ? 42  ILE B CG2 1 
ATOM   5725  C  CD1 . ILE C 2 96  ? 141.026 149.657 104.322 1.00 29.32  ? 42  ILE B CD1 1 
ATOM   5726  N  N   . ASP C 2 97  ? 135.881 152.305 104.149 1.00 34.12  ? 43  ASP B N   1 
ATOM   5727  C  CA  . ASP C 2 97  ? 134.842 152.947 104.947 1.00 32.16  ? 43  ASP B CA  1 
ATOM   5728  C  C   . ASP C 2 97  ? 134.363 151.934 105.976 1.00 33.53  ? 43  ASP B C   1 
ATOM   5729  O  O   . ASP C 2 97  ? 133.758 150.923 105.616 1.00 34.52  ? 43  ASP B O   1 
ATOM   5730  C  CB  . ASP C 2 97  ? 133.701 153.430 104.059 1.00 33.71  ? 43  ASP B CB  1 
ATOM   5731  C  CG  . ASP C 2 97  ? 132.677 154.238 104.815 1.00 45.05  ? 43  ASP B CG  1 
ATOM   5732  O  OD1 . ASP C 2 97  ? 133.004 155.357 105.256 1.00 48.80  ? 43  ASP B OD1 1 
ATOM   5733  O  OD2 . ASP C 2 97  ? 131.538 153.760 104.964 1.00 50.19  ? 43  ASP B OD2 1 
ATOM   5734  N  N   . ILE C 2 98  ? 134.645 152.195 107.246 1.00 34.84  ? 44  ILE B N   1 
ATOM   5735  C  CA  . ILE C 2 98  ? 134.420 151.211 108.299 1.00 33.79  ? 44  ILE B CA  1 
ATOM   5736  C  C   . ILE C 2 98  ? 132.966 151.254 108.740 1.00 33.50  ? 44  ILE B C   1 
ATOM   5737  O  O   . ILE C 2 98  ? 132.444 152.313 109.100 1.00 36.66  ? 44  ILE B O   1 
ATOM   5738  C  CB  . ILE C 2 98  ? 135.359 151.465 109.485 1.00 32.67  ? 44  ILE B CB  1 
ATOM   5739  C  CG1 . ILE C 2 98  ? 136.809 151.460 109.023 1.00 33.43  ? 44  ILE B CG1 1 
ATOM   5740  C  CG2 . ILE C 2 98  ? 135.152 150.429 110.553 1.00 29.31  ? 44  ILE B CG2 1 
ATOM   5741  C  CD1 . ILE C 2 98  ? 137.715 152.223 109.932 1.00 38.88  ? 44  ILE B CD1 1 
ATOM   5742  N  N   . ALA C 2 99  ? 132.305 150.099 108.721 1.00 32.80  ? 45  ALA B N   1 
ATOM   5743  C  CA  . ALA C 2 99  ? 130.937 150.009 109.202 1.00 30.66  ? 45  ALA B CA  1 
ATOM   5744  C  C   . ALA C 2 99  ? 130.890 149.738 110.699 1.00 36.33  ? 45  ALA B C   1 
ATOM   5745  O  O   . ALA C 2 99  ? 130.127 150.380 111.423 1.00 44.42  ? 45  ALA B O   1 
ATOM   5746  C  CB  . ALA C 2 99  ? 130.185 148.918 108.440 1.00 27.49  ? 45  ALA B CB  1 
ATOM   5747  N  N   . SER C 2 100 ? 131.695 148.794 111.176 1.00 34.77  ? 46  SER B N   1 
ATOM   5748  C  CA  . SER C 2 100 ? 131.746 148.481 112.595 1.00 36.28  ? 46  SER B CA  1 
ATOM   5749  C  C   . SER C 2 100 ? 132.951 147.596 112.860 1.00 35.81  ? 46  SER B C   1 
ATOM   5750  O  O   . SER C 2 100 ? 133.518 147.002 111.943 1.00 37.36  ? 46  SER B O   1 
ATOM   5751  C  CB  . SER C 2 100 ? 130.467 147.786 113.063 1.00 41.26  ? 46  SER B CB  1 
ATOM   5752  O  OG  . SER C 2 100 ? 130.287 146.549 112.399 1.00 40.38  ? 46  SER B OG  1 
ATOM   5753  N  N   . ILE C 2 101 ? 133.344 147.535 114.128 1.00 36.64  ? 47  ILE B N   1 
ATOM   5754  C  CA  . ILE C 2 101 ? 134.255 146.515 114.632 1.00 36.06  ? 47  ILE B CA  1 
ATOM   5755  C  C   . ILE C 2 101 ? 133.442 145.688 115.617 1.00 41.66  ? 47  ILE B C   1 
ATOM   5756  O  O   . ILE C 2 101 ? 133.216 146.107 116.756 1.00 46.49  ? 47  ILE B O   1 
ATOM   5757  C  CB  . ILE C 2 101 ? 135.505 147.108 115.285 1.00 33.57  ? 47  ILE B CB  1 
ATOM   5758  C  CG1 . ILE C 2 101 ? 136.371 147.790 114.234 1.00 35.24  ? 47  ILE B CG1 1 
ATOM   5759  C  CG2 . ILE C 2 101 ? 136.314 146.030 115.954 1.00 34.97  ? 47  ILE B CG2 1 
ATOM   5760  C  CD1 . ILE C 2 101 ? 137.682 148.285 114.770 1.00 33.40  ? 47  ILE B CD1 1 
ATOM   5761  N  N   . ASP C 2 102 ? 132.994 144.509 115.181 1.00 45.83  ? 48  ASP B N   1 
ATOM   5762  C  CA  . ASP C 2 102 ? 131.942 143.799 115.902 1.00 46.65  ? 48  ASP B CA  1 
ATOM   5763  C  C   . ASP C 2 102 ? 132.413 143.349 117.278 1.00 49.42  ? 48  ASP B C   1 
ATOM   5764  O  O   . ASP C 2 102 ? 131.748 143.606 118.286 1.00 60.43  ? 48  ASP B O   1 
ATOM   5765  C  CB  . ASP C 2 102 ? 131.456 142.603 115.083 1.00 53.48  ? 48  ASP B CB  1 
ATOM   5766  C  CG  . ASP C 2 102 ? 131.238 142.941 113.612 1.00 57.83  ? 48  ASP B CG  1 
ATOM   5767  O  OD1 . ASP C 2 102 ? 131.580 144.066 113.191 1.00 49.10  ? 48  ASP B OD1 1 
ATOM   5768  O  OD2 . ASP C 2 102 ? 130.723 142.077 112.872 1.00 57.97  ? 48  ASP B OD2 1 
ATOM   5769  N  N   . MET C 2 103 ? 133.557 142.677 117.345 1.00 44.47  ? 49  MET B N   1 
ATOM   5770  C  CA  . MET C 2 103 ? 134.055 142.173 118.613 1.00 48.23  ? 49  MET B CA  1 
ATOM   5771  C  C   . MET C 2 103 ? 135.571 142.133 118.587 1.00 46.86  ? 49  MET B C   1 
ATOM   5772  O  O   . MET C 2 103 ? 136.189 142.126 117.520 1.00 50.92  ? 49  MET B O   1 
ATOM   5773  C  CB  . MET C 2 103 ? 133.498 140.786 118.935 1.00 49.12  ? 49  MET B CB  1 
ATOM   5774  C  CG  . MET C 2 103 ? 133.570 139.818 117.786 1.00 53.02  ? 49  MET B CG  1 
ATOM   5775  S  SD  . MET C 2 103 ? 132.603 138.332 118.087 1.00 90.41  ? 49  MET B SD  1 
ATOM   5776  C  CE  . MET C 2 103 ? 132.623 137.585 116.460 1.00 68.66  ? 49  MET B CE  1 
ATOM   5777  N  N   . VAL C 2 104 ? 136.157 142.133 119.781 1.00 42.49  ? 50  VAL B N   1 
ATOM   5778  C  CA  . VAL C 2 104 ? 137.601 142.170 119.982 1.00 40.65  ? 50  VAL B CA  1 
ATOM   5779  C  C   . VAL C 2 104 ? 137.898 141.129 121.051 1.00 41.27  ? 50  VAL B C   1 
ATOM   5780  O  O   . VAL C 2 104 ? 137.644 141.361 122.236 1.00 48.75  ? 50  VAL B O   1 
ATOM   5781  C  CB  . VAL C 2 104 ? 138.097 143.557 120.399 1.00 38.04  ? 50  VAL B CB  1 
ATOM   5782  C  CG1 . VAL C 2 104 ? 139.581 143.536 120.632 1.00 41.39  ? 50  VAL B CG1 1 
ATOM   5783  C  CG2 . VAL C 2 104 ? 137.756 144.580 119.343 1.00 35.80  ? 50  VAL B CG2 1 
ATOM   5784  N  N   . SER C 2 105 ? 138.423 139.981 120.643 1.00 39.87  ? 51  SER B N   1 
ATOM   5785  C  CA  . SER C 2 105 ? 138.547 138.821 121.512 1.00 43.46  ? 51  SER B CA  1 
ATOM   5786  C  C   . SER C 2 105 ? 139.986 138.663 121.980 1.00 46.52  ? 51  SER B C   1 
ATOM   5787  O  O   . SER C 2 105 ? 140.900 138.514 121.159 1.00 50.21  ? 51  SER B O   1 
ATOM   5788  C  CB  . SER C 2 105 ? 138.085 137.559 120.793 1.00 43.88  ? 51  SER B CB  1 
ATOM   5789  O  OG  . SER C 2 105 ? 138.071 136.461 121.680 1.00 46.75  ? 51  SER B OG  1 
ATOM   5790  N  N   . GLU C 2 106 ? 140.170 138.687 123.301 1.00 47.79  ? 52  GLU B N   1 
ATOM   5791  C  CA  . GLU C 2 106 ? 141.452 138.424 123.938 1.00 48.63  ? 52  GLU B CA  1 
ATOM   5792  C  C   . GLU C 2 106 ? 141.800 136.946 123.992 1.00 47.91  ? 52  GLU B C   1 
ATOM   5793  O  O   . GLU C 2 106 ? 142.987 136.604 123.981 1.00 46.73  ? 52  GLU B O   1 
ATOM   5794  C  CB  . GLU C 2 106 ? 141.462 138.986 125.363 1.00 51.85  ? 52  GLU B CB  1 
ATOM   5795  C  CG  . GLU C 2 106 ? 141.264 140.490 125.456 1.00 53.05  ? 52  GLU B CG  1 
ATOM   5796  C  CD  . GLU C 2 106 ? 139.806 140.893 125.394 1.00 58.91  ? 52  GLU B CD  1 
ATOM   5797  O  OE1 . GLU C 2 106 ? 138.939 140.001 125.493 1.00 59.57  ? 52  GLU B OE1 1 
ATOM   5798  O  OE2 . GLU C 2 106 ? 139.527 142.101 125.247 1.00 56.19  ? 52  GLU B OE2 1 
ATOM   5799  N  N   . VAL C 2 107 ? 140.803 136.068 124.089 1.00 49.41  ? 53  VAL B N   1 
ATOM   5800  C  CA  . VAL C 2 107 ? 141.066 134.635 124.134 1.00 48.29  ? 53  VAL B CA  1 
ATOM   5801  C  C   . VAL C 2 107 ? 141.507 134.124 122.772 1.00 49.07  ? 53  VAL B C   1 
ATOM   5802  O  O   . VAL C 2 107 ? 142.515 133.420 122.652 1.00 49.81  ? 53  VAL B O   1 
ATOM   5803  C  CB  . VAL C 2 107 ? 139.822 133.886 124.637 1.00 51.59  ? 53  VAL B CB  1 
ATOM   5804  C  CG1 . VAL C 2 107 ? 140.111 132.405 124.744 1.00 54.53  ? 53  VAL B CG1 1 
ATOM   5805  C  CG2 . VAL C 2 107 ? 139.388 134.442 125.968 1.00 60.45  ? 53  VAL B CG2 1 
ATOM   5806  N  N   . ASN C 2 108 ? 140.758 134.470 121.727 1.00 48.11  ? 54  ASN B N   1 
ATOM   5807  C  CA  . ASN C 2 108 ? 141.109 134.094 120.366 1.00 42.42  ? 54  ASN B CA  1 
ATOM   5808  C  C   . ASN C 2 108 ? 142.137 135.024 119.749 1.00 41.65  ? 54  ASN B C   1 
ATOM   5809  O  O   . ASN C 2 108 ? 142.675 134.700 118.688 1.00 45.21  ? 54  ASN B O   1 
ATOM   5810  C  CB  . ASN C 2 108 ? 139.862 134.070 119.488 1.00 41.29  ? 54  ASN B CB  1 
ATOM   5811  C  CG  . ASN C 2 108 ? 138.863 133.042 119.935 1.00 47.23  ? 54  ASN B CG  1 
ATOM   5812  O  OD1 . ASN C 2 108 ? 138.872 131.909 119.464 1.00 54.32  ? 54  ASN B OD1 1 
ATOM   5813  N  ND2 . ASN C 2 108 ? 137.989 133.428 120.848 1.00 51.93  ? 54  ASN B ND2 1 
ATOM   5814  N  N   . MET C 2 109 ? 142.405 136.164 120.382 1.00 42.29  ? 55  MET B N   1 
ATOM   5815  C  CA  . MET C 2 109 ? 143.425 137.111 119.943 1.00 42.20  ? 55  MET B CA  1 
ATOM   5816  C  C   . MET C 2 109 ? 143.136 137.632 118.537 1.00 43.38  ? 55  MET B C   1 
ATOM   5817  O  O   . MET C 2 109 ? 143.965 137.538 117.635 1.00 44.50  ? 55  MET B O   1 
ATOM   5818  C  CB  . MET C 2 109 ? 144.817 136.478 120.013 1.00 41.40  ? 55  MET B CB  1 
ATOM   5819  C  CG  . MET C 2 109 ? 145.312 136.219 121.412 1.00 49.18  ? 55  MET B CG  1 
ATOM   5820  S  SD  . MET C 2 109 ? 145.871 137.717 122.228 1.00 69.16  ? 55  MET B SD  1 
ATOM   5821  C  CE  . MET C 2 109 ? 146.384 137.054 123.807 1.00 58.01  ? 55  MET B CE  1 
ATOM   5822  N  N   . ASP C 2 110 ? 141.950 138.205 118.362 1.00 41.81  ? 56  ASP B N   1 
ATOM   5823  C  CA  . ASP C 2 110 ? 141.610 138.755 117.052 1.00 37.20  ? 56  ASP B CA  1 
ATOM   5824  C  C   . ASP C 2 110 ? 140.488 139.774 117.208 1.00 39.42  ? 56  ASP B C   1 
ATOM   5825  O  O   . ASP C 2 110 ? 140.102 140.130 118.323 1.00 45.35  ? 56  ASP B O   1 
ATOM   5826  C  CB  . ASP C 2 110 ? 141.248 137.643 116.063 1.00 36.91  ? 56  ASP B CB  1 
ATOM   5827  C  CG  . ASP C 2 110 ? 140.098 136.788 116.531 1.00 44.54  ? 56  ASP B CG  1 
ATOM   5828  O  OD1 . ASP C 2 110 ? 139.028 137.335 116.852 1.00 44.52  ? 56  ASP B OD1 1 
ATOM   5829  O  OD2 . ASP C 2 110 ? 140.251 135.554 116.554 1.00 48.57  ? 56  ASP B OD2 1 
ATOM   5830  N  N   . TYR C 2 111 ? 139.981 140.262 116.080 1.00 37.17  ? 57  TYR B N   1 
ATOM   5831  C  CA  . TYR C 2 111 ? 138.883 141.219 116.082 1.00 33.06  ? 57  TYR B CA  1 
ATOM   5832  C  C   . TYR C 2 111 ? 138.173 141.143 114.741 1.00 33.93  ? 57  TYR B C   1 
ATOM   5833  O  O   . TYR C 2 111 ? 138.790 140.856 113.718 1.00 36.08  ? 57  TYR B O   1 
ATOM   5834  C  CB  . TYR C 2 111 ? 139.379 142.643 116.341 1.00 31.55  ? 57  TYR B CB  1 
ATOM   5835  C  CG  . TYR C 2 111 ? 140.184 143.201 115.199 1.00 33.86  ? 57  TYR B CG  1 
ATOM   5836  C  CD1 . TYR C 2 111 ? 141.503 142.834 115.016 1.00 35.80  ? 57  TYR B CD1 1 
ATOM   5837  C  CD2 . TYR C 2 111 ? 139.620 144.076 114.294 1.00 34.98  ? 57  TYR B CD2 1 
ATOM   5838  C  CE1 . TYR C 2 111 ? 142.234 143.328 113.973 1.00 35.97  ? 57  TYR B CE1 1 
ATOM   5839  C  CE2 . TYR C 2 111 ? 140.344 144.573 113.246 1.00 35.35  ? 57  TYR B CE2 1 
ATOM   5840  C  CZ  . TYR C 2 111 ? 141.650 144.196 113.089 1.00 36.76  ? 57  TYR B CZ  1 
ATOM   5841  O  OH  . TYR C 2 111 ? 142.379 144.697 112.042 1.00 38.78  ? 57  TYR B OH  1 
ATOM   5842  N  N   . THR C 2 112 ? 136.876 141.422 114.754 1.00 36.61  ? 58  THR B N   1 
ATOM   5843  C  CA  . THR C 2 112 ? 136.048 141.323 113.558 1.00 33.83  ? 58  THR B CA  1 
ATOM   5844  C  C   . THR C 2 112 ? 135.718 142.709 113.015 1.00 36.86  ? 58  THR B C   1 
ATOM   5845  O  O   . THR C 2 112 ? 135.221 143.565 113.750 1.00 40.98  ? 58  THR B O   1 
ATOM   5846  C  CB  . THR C 2 112 ? 134.767 140.552 113.860 1.00 35.92  ? 58  THR B CB  1 
ATOM   5847  O  OG1 . THR C 2 112 ? 135.101 139.234 114.297 1.00 40.52  ? 58  THR B OG1 1 
ATOM   5848  C  CG2 . THR C 2 112 ? 133.914 140.451 112.626 1.00 35.86  ? 58  THR B CG2 1 
ATOM   5849  N  N   . LEU C 2 113 ? 135.975 142.917 111.724 1.00 33.64  ? 59  LEU B N   1 
ATOM   5850  C  CA  . LEU C 2 113 ? 135.854 144.218 111.079 1.00 31.15  ? 59  LEU B CA  1 
ATOM   5851  C  C   . LEU C 2 113 ? 134.970 144.107 109.847 1.00 31.40  ? 59  LEU B C   1 
ATOM   5852  O  O   . LEU C 2 113 ? 135.152 143.201 109.033 1.00 34.88  ? 59  LEU B O   1 
ATOM   5853  C  CB  . LEU C 2 113 ? 137.235 144.751 110.681 1.00 30.36  ? 59  LEU B CB  1 
ATOM   5854  C  CG  . LEU C 2 113 ? 137.300 145.952 109.738 1.00 31.73  ? 59  LEU B CG  1 
ATOM   5855  C  CD1 . LEU C 2 113 ? 136.889 147.217 110.448 1.00 33.99  ? 59  LEU B CD1 1 
ATOM   5856  C  CD2 . LEU C 2 113 ? 138.679 146.103 109.146 1.00 32.19  ? 59  LEU B CD2 1 
ATOM   5857  N  N   . THR C 2 114 ? 134.027 145.032 109.701 1.00 29.83  ? 60  THR B N   1 
ATOM   5858  C  CA  . THR C 2 114 ? 133.180 145.123 108.518 1.00 28.08  ? 60  THR B CA  1 
ATOM   5859  C  C   . THR C 2 114 ? 133.481 146.429 107.800 1.00 29.83  ? 60  THR B C   1 
ATOM   5860  O  O   . THR C 2 114 ? 133.552 147.484 108.433 1.00 34.45  ? 60  THR B O   1 
ATOM   5861  C  CB  . THR C 2 114 ? 131.699 145.052 108.889 1.00 29.58  ? 60  THR B CB  1 
ATOM   5862  O  OG1 . THR C 2 114 ? 131.442 143.834 109.592 1.00 37.81  ? 60  THR B OG1 1 
ATOM   5863  C  CG2 . THR C 2 114 ? 130.841 145.072 107.647 1.00 27.45  ? 60  THR B CG2 1 
ATOM   5864  N  N   . MET C 2 115 ? 133.654 146.366 106.483 1.00 29.49  ? 61  MET B N   1 
ATOM   5865  C  CA  . MET C 2 115 ? 134.095 147.549 105.764 1.00 28.70  ? 61  MET B CA  1 
ATOM   5866  C  C   . MET C 2 115 ? 133.600 147.533 104.328 1.00 28.11  ? 61  MET B C   1 
ATOM   5867  O  O   . MET C 2 115 ? 133.278 146.485 103.766 1.00 27.55  ? 61  MET B O   1 
ATOM   5868  C  CB  . MET C 2 115 ? 135.619 147.657 105.778 1.00 29.61  ? 61  MET B CB  1 
ATOM   5869  C  CG  . MET C 2 115 ? 136.308 146.383 105.369 1.00 30.45  ? 61  MET B CG  1 
ATOM   5870  S  SD  . MET C 2 115 ? 138.088 146.554 105.304 1.00 44.38  ? 61  MET B SD  1 
ATOM   5871  C  CE  . MET C 2 115 ? 138.541 144.908 104.791 1.00 33.44  ? 61  MET B CE  1 
ATOM   5872  N  N   . TYR C 2 116 ? 133.546 148.728 103.745 1.00 29.16  ? 62  TYR B N   1 
ATOM   5873  C  CA  . TYR C 2 116 ? 133.431 148.913 102.305 1.00 27.77  ? 62  TYR B CA  1 
ATOM   5874  C  C   . TYR C 2 116 ? 134.834 149.191 101.791 1.00 30.88  ? 62  TYR B C   1 
ATOM   5875  O  O   . TYR C 2 116 ? 135.463 150.173 102.189 1.00 35.07  ? 62  TYR B O   1 
ATOM   5876  C  CB  . TYR C 2 116 ? 132.495 150.067 101.956 1.00 29.18  ? 62  TYR B CB  1 
ATOM   5877  C  CG  . TYR C 2 116 ? 131.080 149.934 102.459 1.00 35.04  ? 62  TYR B CG  1 
ATOM   5878  C  CD1 . TYR C 2 116 ? 130.764 150.204 103.780 1.00 35.94  ? 62  TYR B CD1 1 
ATOM   5879  C  CD2 . TYR C 2 116 ? 130.055 149.564 101.606 1.00 34.57  ? 62  TYR B CD2 1 
ATOM   5880  C  CE1 . TYR C 2 116 ? 129.475 150.093 104.239 1.00 38.61  ? 62  TYR B CE1 1 
ATOM   5881  C  CE2 . TYR C 2 116 ? 128.761 149.452 102.058 1.00 33.88  ? 62  TYR B CE2 1 
ATOM   5882  C  CZ  . TYR C 2 116 ? 128.477 149.720 103.374 1.00 39.15  ? 62  TYR B CZ  1 
ATOM   5883  O  OH  . TYR C 2 116 ? 127.190 149.610 103.833 1.00 43.89  ? 62  TYR B OH  1 
ATOM   5884  N  N   . PHE C 2 117 ? 135.319 148.326 100.916 1.00 26.63  ? 63  PHE B N   1 
ATOM   5885  C  CA  . PHE C 2 117 ? 136.676 148.375 100.400 1.00 24.59  ? 63  PHE B CA  1 
ATOM   5886  C  C   . PHE C 2 117 ? 136.609 148.736 98.923  1.00 25.86  ? 63  PHE B C   1 
ATOM   5887  O  O   . PHE C 2 117 ? 136.075 147.966 98.120  1.00 32.79  ? 63  PHE B O   1 
ATOM   5888  C  CB  . PHE C 2 117 ? 137.349 147.022 100.624 1.00 24.55  ? 63  PHE B CB  1 
ATOM   5889  C  CG  . PHE C 2 117 ? 138.773 146.958 100.187 1.00 27.76  ? 63  PHE B CG  1 
ATOM   5890  C  CD1 . PHE C 2 117 ? 139.762 147.617 100.887 1.00 32.55  ? 63  PHE B CD1 1 
ATOM   5891  C  CD2 . PHE C 2 117 ? 139.131 146.202 99.097  1.00 26.00  ? 63  PHE B CD2 1 
ATOM   5892  C  CE1 . PHE C 2 117 ? 141.072 147.542 100.482 1.00 30.90  ? 63  PHE B CE1 1 
ATOM   5893  C  CE2 . PHE C 2 117 ? 140.433 146.124 98.696  1.00 27.22  ? 63  PHE B CE2 1 
ATOM   5894  C  CZ  . PHE C 2 117 ? 141.405 146.791 99.387  1.00 31.23  ? 63  PHE B CZ  1 
ATOM   5895  N  N   . GLN C 2 118 ? 137.131 149.907 98.568  1.00 25.49  ? 64  GLN B N   1 
ATOM   5896  C  CA  . GLN C 2 118 ? 137.055 150.427 97.212  1.00 28.86  ? 64  GLN B CA  1 
ATOM   5897  C  C   . GLN C 2 118 ? 138.446 150.502 96.602  1.00 31.95  ? 64  GLN B C   1 
ATOM   5898  O  O   . GLN C 2 118 ? 139.383 150.993 97.233  1.00 35.17  ? 64  GLN B O   1 
ATOM   5899  C  CB  . GLN C 2 118 ? 136.409 151.816 97.183  1.00 30.68  ? 64  GLN B CB  1 
ATOM   5900  C  CG  . GLN C 2 118 ? 134.906 151.820 96.963  1.00 37.60  ? 64  GLN B CG  1 
ATOM   5901  C  CD  . GLN C 2 118 ? 134.109 151.868 98.255  1.00 45.41  ? 64  GLN B CD  1 
ATOM   5902  O  OE1 . GLN C 2 118 ? 134.551 152.438 99.252  1.00 46.10  ? 64  GLN B OE1 1 
ATOM   5903  N  NE2 . GLN C 2 118 ? 132.921 151.271 98.240  1.00 38.05  ? 64  GLN B NE2 1 
ATOM   5904  N  N   . GLN C 2 119 ? 138.566 150.031 95.363  1.00 29.42  ? 65  GLN B N   1 
ATOM   5905  C  CA  . GLN C 2 119 ? 139.812 150.040 94.613  1.00 26.58  ? 65  GLN B CA  1 
ATOM   5906  C  C   . GLN C 2 119 ? 139.618 150.831 93.330  1.00 28.47  ? 65  GLN B C   1 
ATOM   5907  O  O   . GLN C 2 119 ? 138.595 150.689 92.654  1.00 34.49  ? 65  GLN B O   1 
ATOM   5908  C  CB  . GLN C 2 119 ? 140.274 148.619 94.310  1.00 28.07  ? 65  GLN B CB  1 
ATOM   5909  C  CG  . GLN C 2 119 ? 140.910 147.950 95.506  1.00 31.36  ? 65  GLN B CG  1 
ATOM   5910  C  CD  . GLN C 2 119 ? 141.059 146.463 95.349  1.00 32.79  ? 65  GLN B CD  1 
ATOM   5911  O  OE1 . GLN C 2 119 ? 142.153 145.928 95.457  1.00 34.11  ? 65  GLN B OE1 1 
ATOM   5912  N  NE2 . GLN C 2 119 ? 139.955 145.781 95.106  1.00 31.10  ? 65  GLN B NE2 1 
ATOM   5913  N  N   . TYR C 2 120 ? 140.603 151.659 93.007  1.00 30.51  ? 66  TYR B N   1 
ATOM   5914  C  CA  A TYR C 2 120 ? 140.545 152.581 91.877  0.50 33.68  ? 66  TYR B CA  1 
ATOM   5915  C  CA  B TYR C 2 120 ? 140.547 152.588 91.889  0.50 33.55  ? 66  TYR B CA  1 
ATOM   5916  C  C   . TYR C 2 120 ? 141.761 152.358 91.001  1.00 33.01  ? 66  TYR B C   1 
ATOM   5917  O  O   . TYR C 2 120 ? 142.894 152.462 91.472  1.00 36.42  ? 66  TYR B O   1 
ATOM   5918  C  CB  A TYR C 2 120 ? 140.534 154.040 92.328  0.50 36.36  ? 66  TYR B CB  1 
ATOM   5919  C  CB  B TYR C 2 120 ? 140.527 154.011 92.441  0.50 36.51  ? 66  TYR B CB  1 
ATOM   5920  C  CG  A TYR C 2 120 ? 139.231 154.564 92.861  0.50 36.71  ? 66  TYR B CG  1 
ATOM   5921  C  CG  B TYR C 2 120 ? 140.135 155.105 91.498  0.50 37.73  ? 66  TYR B CG  1 
ATOM   5922  C  CD1 A TYR C 2 120 ? 138.292 155.127 92.016  0.50 36.46  ? 66  TYR B CD1 1 
ATOM   5923  C  CD1 B TYR C 2 120 ? 138.802 155.366 91.230  0.50 37.38  ? 66  TYR B CD1 1 
ATOM   5924  C  CD2 A TYR C 2 120 ? 138.956 154.530 94.219  0.50 35.97  ? 66  TYR B CD2 1 
ATOM   5925  C  CD2 B TYR C 2 120 ? 141.098 155.920 90.914  0.50 38.41  ? 66  TYR B CD2 1 
ATOM   5926  C  CE1 A TYR C 2 120 ? 137.110 155.623 92.507  0.50 37.14  ? 66  TYR B CE1 1 
ATOM   5927  C  CE1 B TYR C 2 120 ? 138.439 156.387 90.378  0.50 41.10  ? 66  TYR B CE1 1 
ATOM   5928  C  CE2 A TYR C 2 120 ? 137.781 155.018 94.719  0.50 36.74  ? 66  TYR B CE2 1 
ATOM   5929  C  CE2 B TYR C 2 120 ? 140.746 156.943 90.067  0.50 38.73  ? 66  TYR B CE2 1 
ATOM   5930  C  CZ  A TYR C 2 120 ? 136.860 155.567 93.864  0.50 38.02  ? 66  TYR B CZ  1 
ATOM   5931  C  CZ  B TYR C 2 120 ? 139.415 157.176 89.805  0.50 42.14  ? 66  TYR B CZ  1 
ATOM   5932  O  OH  A TYR C 2 120 ? 135.680 156.056 94.369  0.50 38.53  ? 66  TYR B OH  1 
ATOM   5933  O  OH  B TYR C 2 120 ? 139.055 158.194 88.955  0.50 43.06  ? 66  TYR B OH  1 
ATOM   5934  N  N   . TRP C 2 121 ? 141.539 152.070 89.723  1.00 33.41  ? 67  TRP B N   1 
ATOM   5935  C  CA  . TRP C 2 121 ? 142.686 151.941 88.831  1.00 33.88  ? 67  TRP B CA  1 
ATOM   5936  C  C   . TRP C 2 121 ? 142.281 152.344 87.427  1.00 37.19  ? 67  TRP B C   1 
ATOM   5937  O  O   . TRP C 2 121 ? 141.133 152.694 87.171  1.00 41.88  ? 67  TRP B O   1 
ATOM   5938  C  CB  . TRP C 2 121 ? 143.290 150.533 88.861  1.00 32.28  ? 67  TRP B CB  1 
ATOM   5939  C  CG  . TRP C 2 121 ? 142.463 149.472 88.243  1.00 32.77  ? 67  TRP B CG  1 
ATOM   5940  C  CD1 . TRP C 2 121 ? 142.549 149.002 86.970  1.00 33.79  ? 67  TRP B CD1 1 
ATOM   5941  C  CD2 . TRP C 2 121 ? 141.434 148.721 88.881  1.00 30.09  ? 67  TRP B CD2 1 
ATOM   5942  N  NE1 . TRP C 2 121 ? 141.624 148.012 86.771  1.00 31.52  ? 67  TRP B NE1 1 
ATOM   5943  C  CE2 . TRP C 2 121 ? 140.929 147.818 87.933  1.00 29.86  ? 67  TRP B CE2 1 
ATOM   5944  C  CE3 . TRP C 2 121 ? 140.889 148.726 90.163  1.00 28.55  ? 67  TRP B CE3 1 
ATOM   5945  C  CZ2 . TRP C 2 121 ? 139.904 146.937 88.224  1.00 29.72  ? 67  TRP B CZ2 1 
ATOM   5946  C  CZ3 . TRP C 2 121 ? 139.875 147.849 90.449  1.00 29.85  ? 67  TRP B CZ3 1 
ATOM   5947  C  CH2 . TRP C 2 121 ? 139.390 146.969 89.486  1.00 29.27  ? 67  TRP B CH2 1 
ATOM   5948  N  N   . ARG C 2 122 ? 143.241 152.322 86.513  1.00 37.29  ? 68  ARG B N   1 
ATOM   5949  C  CA  . ARG C 2 122 ? 143.011 152.729 85.137  1.00 42.96  ? 68  ARG B CA  1 
ATOM   5950  C  C   . ARG C 2 122 ? 143.371 151.586 84.206  1.00 45.80  ? 68  ARG B C   1 
ATOM   5951  O  O   . ARG C 2 122 ? 144.455 151.010 84.315  1.00 48.11  ? 68  ARG B O   1 
ATOM   5952  C  CB  . ARG C 2 122 ? 143.825 153.973 84.782  1.00 43.94  ? 68  ARG B CB  1 
ATOM   5953  C  CG  . ARG C 2 122 ? 143.725 154.359 83.322  1.00 51.16  ? 68  ARG B CG  1 
ATOM   5954  C  CD  . ARG C 2 122 ? 144.122 155.798 83.090  1.00 61.62  ? 68  ARG B CD  1 
ATOM   5955  N  NE  . ARG C 2 122 ? 144.165 156.117 81.670  1.00 72.54  ? 68  ARG B NE  1 
ATOM   5956  C  CZ  . ARG C 2 122 ? 144.450 157.315 81.180  1.00 79.17  ? 68  ARG B CZ  1 
ATOM   5957  N  NH1 . ARG C 2 122 ? 144.703 158.344 81.973  1.00 81.59  ? 68  ARG B NH1 1 
ATOM   5958  N  NH2 . ARG C 2 122 ? 144.481 157.486 79.862  1.00 75.12  ? 68  ARG B NH2 1 
ATOM   5959  N  N   . ASP C 2 123 ? 142.463 151.271 83.289  1.00 47.44  ? 69  ASP B N   1 
ATOM   5960  C  CA  . ASP C 2 123 ? 142.675 150.237 82.284  1.00 46.71  ? 69  ASP B CA  1 
ATOM   5961  C  C   . ASP C 2 123 ? 142.376 150.852 80.925  1.00 48.84  ? 69  ASP B C   1 
ATOM   5962  O  O   . ASP C 2 123 ? 141.231 151.215 80.646  1.00 52.42  ? 69  ASP B O   1 
ATOM   5963  C  CB  . ASP C 2 123 ? 141.787 149.026 82.549  1.00 44.62  ? 69  ASP B CB  1 
ATOM   5964  C  CG  . ASP C 2 123 ? 142.222 147.807 81.776  1.00 48.03  ? 69  ASP B CG  1 
ATOM   5965  O  OD1 . ASP C 2 123 ? 143.184 147.913 80.993  1.00 50.38  ? 69  ASP B OD1 1 
ATOM   5966  O  OD2 . ASP C 2 123 ? 141.605 146.739 81.952  1.00 50.33  ? 69  ASP B OD2 1 
ATOM   5967  N  N   . LYS C 2 124 ? 143.402 150.985 80.084  1.00 47.69  ? 70  LYS B N   1 
ATOM   5968  C  CA  . LYS C 2 124 ? 143.194 151.591 78.777  1.00 49.42  ? 70  LYS B CA  1 
ATOM   5969  C  C   . LYS C 2 124 ? 142.383 150.700 77.847  1.00 49.52  ? 70  LYS B C   1 
ATOM   5970  O  O   . LYS C 2 124 ? 141.810 151.202 76.876  1.00 54.04  ? 70  LYS B O   1 
ATOM   5971  C  CB  . LYS C 2 124 ? 144.531 151.932 78.123  1.00 56.18  ? 70  LYS B CB  1 
ATOM   5972  C  CG  . LYS C 2 124 ? 145.355 152.956 78.876  1.00 65.50  ? 70  LYS B CG  1 
ATOM   5973  C  CD  . LYS C 2 124 ? 146.623 153.307 78.106  1.00 72.21  ? 70  LYS B CD  1 
ATOM   5974  C  CE  . LYS C 2 124 ? 147.540 154.206 78.918  1.00 73.72  ? 70  LYS B CE  1 
ATOM   5975  N  NZ  . LYS C 2 124 ? 146.853 155.455 79.336  1.00 73.74  ? 70  LYS B NZ  1 
ATOM   5976  N  N   . ARG C 2 125 ? 142.321 149.396 78.115  1.00 46.35  ? 71  ARG B N   1 
ATOM   5977  C  CA  . ARG C 2 125 ? 141.533 148.512 77.267  1.00 45.32  ? 71  ARG B CA  1 
ATOM   5978  C  C   . ARG C 2 125 ? 140.042 148.791 77.371  1.00 46.51  ? 71  ARG B C   1 
ATOM   5979  O  O   . ARG C 2 125 ? 139.288 148.392 76.479  1.00 48.41  ? 71  ARG B O   1 
ATOM   5980  C  CB  . ARG C 2 125 ? 141.814 147.051 77.620  1.00 44.31  ? 71  ARG B CB  1 
ATOM   5981  C  CG  . ARG C 2 125 ? 143.214 146.591 77.280  1.00 45.10  ? 71  ARG B CG  1 
ATOM   5982  C  CD  . ARG C 2 125 ? 143.453 145.152 77.706  1.00 46.43  ? 71  ARG B CD  1 
ATOM   5983  N  NE  . ARG C 2 125 ? 143.555 145.007 79.152  1.00 48.05  ? 71  ARG B NE  1 
ATOM   5984  C  CZ  . ARG C 2 125 ? 143.755 143.854 79.773  1.00 47.21  ? 71  ARG B CZ  1 
ATOM   5985  N  NH1 . ARG C 2 125 ? 143.870 142.722 79.105  1.00 46.59  ? 71  ARG B NH1 1 
ATOM   5986  N  NH2 . ARG C 2 125 ? 143.828 143.836 81.099  1.00 44.34  ? 71  ARG B NH2 1 
ATOM   5987  N  N   . LEU C 2 126 ? 139.601 149.464 78.429  1.00 47.14  ? 72  LEU B N   1 
ATOM   5988  C  CA  . LEU C 2 126 ? 138.191 149.745 78.653  1.00 47.79  ? 72  LEU B CA  1 
ATOM   5989  C  C   . LEU C 2 126 ? 137.819 151.188 78.344  1.00 52.31  ? 72  LEU B C   1 
ATOM   5990  O  O   . LEU C 2 126 ? 136.737 151.633 78.733  1.00 56.40  ? 72  LEU B O   1 
ATOM   5991  C  CB  . LEU C 2 126 ? 137.807 149.411 80.093  1.00 43.27  ? 72  LEU B CB  1 
ATOM   5992  C  CG  . LEU C 2 126 ? 138.173 148.018 80.596  1.00 39.43  ? 72  LEU B CG  1 
ATOM   5993  C  CD1 . LEU C 2 126 ? 137.640 147.816 81.993  1.00 41.01  ? 72  LEU B CD1 1 
ATOM   5994  C  CD2 . LEU C 2 126 ? 137.631 146.961 79.669  1.00 44.01  ? 72  LEU B CD2 1 
ATOM   5995  N  N   . ALA C 2 127 ? 138.690 151.933 77.675  1.00 51.59  ? 73  ALA B N   1 
ATOM   5996  C  CA  . ALA C 2 127 ? 138.364 153.302 77.303  1.00 52.79  ? 73  ALA B CA  1 
ATOM   5997  C  C   . ALA C 2 127 ? 137.334 153.309 76.181  1.00 57.27  ? 73  ALA B C   1 
ATOM   5998  O  O   . ALA C 2 127 ? 137.453 152.555 75.212  1.00 58.04  ? 73  ALA B O   1 
ATOM   5999  C  CB  . ALA C 2 127 ? 139.623 154.049 76.875  1.00 51.61  ? 73  ALA B CB  1 
ATOM   6000  N  N   . TYR C 2 128 ? 136.319 154.157 76.317  1.00 60.29  ? 74  TYR B N   1 
ATOM   6001  C  CA  . TYR C 2 128 ? 135.254 154.274 75.333  1.00 60.29  ? 74  TYR B CA  1 
ATOM   6002  C  C   . TYR C 2 128 ? 134.960 155.742 75.070  1.00 65.82  ? 74  TYR B C   1 
ATOM   6003  O  O   . TYR C 2 128 ? 135.152 156.595 75.939  1.00 63.64  ? 74  TYR B O   1 
ATOM   6004  C  CB  . TYR C 2 128 ? 133.978 153.564 75.794  1.00 56.79  ? 74  TYR B CB  1 
ATOM   6005  C  CG  . TYR C 2 128 ? 133.443 154.065 77.109  1.00 59.05  ? 74  TYR B CG  1 
ATOM   6006  C  CD1 . TYR C 2 128 ? 133.912 153.559 78.308  1.00 56.08  ? 74  TYR B CD1 1 
ATOM   6007  C  CD2 . TYR C 2 128 ? 132.466 155.041 77.151  1.00 61.34  ? 74  TYR B CD2 1 
ATOM   6008  C  CE1 . TYR C 2 128 ? 133.429 154.014 79.505  1.00 51.61  ? 74  TYR B CE1 1 
ATOM   6009  C  CE2 . TYR C 2 128 ? 131.977 155.501 78.343  1.00 57.41  ? 74  TYR B CE2 1 
ATOM   6010  C  CZ  . TYR C 2 128 ? 132.463 154.986 79.517  1.00 53.49  ? 74  TYR B CZ  1 
ATOM   6011  O  OH  . TYR C 2 128 ? 131.972 155.443 80.711  1.00 54.33  ? 74  TYR B OH  1 
ATOM   6012  N  N   . SER C 2 129 ? 134.480 156.030 73.865  1.00 71.83  ? 75  SER B N   1 
ATOM   6013  C  CA  . SER C 2 129 ? 134.221 157.397 73.445  1.00 79.59  ? 75  SER B CA  1 
ATOM   6014  C  C   . SER C 2 129 ? 132.821 157.506 72.868  1.00 82.20  ? 75  SER B C   1 
ATOM   6015  O  O   . SER C 2 129 ? 132.271 156.535 72.343  1.00 82.43  ? 75  SER B O   1 
ATOM   6016  C  CB  . SER C 2 129 ? 135.239 157.867 72.404  1.00 79.58  ? 75  SER B CB  1 
ATOM   6017  O  OG  . SER C 2 129 ? 135.147 157.088 71.228  1.00 80.70  ? 75  SER B OG  1 
ATOM   6018  N  N   . GLY C 2 130 ? 132.249 158.702 72.971  1.00 81.78  ? 76  GLY B N   1 
ATOM   6019  C  CA  . GLY C 2 130 ? 130.938 158.983 72.442  1.00 82.37  ? 76  GLY B CA  1 
ATOM   6020  C  C   . GLY C 2 130 ? 129.818 158.907 73.456  1.00 83.97  ? 76  GLY B C   1 
ATOM   6021  O  O   . GLY C 2 130 ? 128.710 159.367 73.166  1.00 89.21  ? 76  GLY B O   1 
ATOM   6022  N  N   . ILE C 2 131 ? 130.073 158.337 74.628  1.00 81.05  ? 77  ILE B N   1 
ATOM   6023  C  CA  . ILE C 2 131 ? 129.097 158.279 75.708  1.00 79.76  ? 77  ILE B CA  1 
ATOM   6024  C  C   . ILE C 2 131 ? 129.619 159.154 76.845  1.00 78.72  ? 77  ILE B C   1 
ATOM   6025  O  O   . ILE C 2 131 ? 130.566 158.761 77.541  1.00 76.29  ? 77  ILE B O   1 
ATOM   6026  C  CB  . ILE C 2 131 ? 128.851 156.842 76.182  1.00 78.62  ? 77  ILE B CB  1 
ATOM   6027  C  CG1 . ILE C 2 131 ? 128.493 155.948 74.998  1.00 79.08  ? 77  ILE B CG1 1 
ATOM   6028  C  CG2 . ILE C 2 131 ? 127.733 156.815 77.203  1.00 76.80  ? 77  ILE B CG2 1 
ATOM   6029  C  CD1 . ILE C 2 131 ? 128.018 154.576 75.394  1.00 78.66  ? 77  ILE B CD1 1 
ATOM   6030  N  N   . PRO C 2 132 ? 129.063 160.338 77.057  1.00 80.50  ? 78  PRO B N   1 
ATOM   6031  C  CA  . PRO C 2 132 ? 129.533 161.237 78.119  1.00 78.95  ? 78  PRO B CA  1 
ATOM   6032  C  C   . PRO C 2 132 ? 128.952 160.916 79.494  1.00 75.06  ? 78  PRO B C   1 
ATOM   6033  O  O   . PRO C 2 132 ? 128.444 161.792 80.193  1.00 77.84  ? 78  PRO B O   1 
ATOM   6034  C  CB  . PRO C 2 132 ? 129.076 162.610 77.619  1.00 80.83  ? 78  PRO B CB  1 
ATOM   6035  C  CG  . PRO C 2 132 ? 127.823 162.314 76.869  1.00 82.70  ? 78  PRO B CG  1 
ATOM   6036  C  CD  . PRO C 2 132 ? 128.031 160.969 76.216  1.00 79.99  ? 78  PRO B CD  1 
ATOM   6037  N  N   . LEU C 2 133 ? 129.028 159.647 79.885  1.00 72.11  ? 79  LEU B N   1 
ATOM   6038  C  CA  . LEU C 2 133 ? 128.490 159.196 81.158  1.00 69.59  ? 79  LEU B CA  1 
ATOM   6039  C  C   . LEU C 2 133 ? 129.438 158.190 81.788  1.00 61.17  ? 79  LEU B C   1 
ATOM   6040  O  O   . LEU C 2 133 ? 130.215 157.523 81.104  1.00 59.19  ? 79  LEU B O   1 
ATOM   6041  C  CB  . LEU C 2 133 ? 127.105 158.560 80.996  1.00 72.67  ? 79  LEU B CB  1 
ATOM   6042  C  CG  . LEU C 2 133 ? 125.922 159.438 80.595  1.00 73.43  ? 79  LEU B CG  1 
ATOM   6043  C  CD1 . LEU C 2 133 ? 124.659 158.596 80.530  1.00 72.41  ? 79  LEU B CD1 1 
ATOM   6044  C  CD2 . LEU C 2 133 ? 125.743 160.585 81.569  1.00 69.77  ? 79  LEU B CD2 1 
ATOM   6045  N  N   . ASN C 2 134 ? 129.355 158.084 83.109  1.00 57.40  ? 80  ASN B N   1 
ATOM   6046  C  CA  . ASN C 2 134 ? 130.065 157.058 83.858  1.00 53.25  ? 80  ASN B CA  1 
ATOM   6047  C  C   . ASN C 2 134 ? 129.145 155.854 84.013  1.00 55.02  ? 80  ASN B C   1 
ATOM   6048  O  O   . ASN C 2 134 ? 128.097 155.951 84.656  1.00 59.64  ? 80  ASN B O   1 
ATOM   6049  C  CB  . ASN C 2 134 ? 130.495 157.596 85.219  1.00 54.35  ? 80  ASN B CB  1 
ATOM   6050  C  CG  . ASN C 2 134 ? 131.442 158.768 85.106  1.00 58.60  ? 80  ASN B CG  1 
ATOM   6051  O  OD1 . ASN C 2 134 ? 132.342 158.767 84.275  1.00 59.52  ? 80  ASN B OD1 1 
ATOM   6052  N  ND2 . ASN C 2 134 ? 131.245 159.777 85.936  1.00 62.71  ? 80  ASN B ND2 1 
ATOM   6053  N  N   . LEU C 2 135 ? 129.537 154.723 83.436  1.00 51.06  ? 81  LEU B N   1 
ATOM   6054  C  CA  . LEU C 2 135 ? 128.651 153.571 83.319  1.00 47.12  ? 81  LEU B CA  1 
ATOM   6055  C  C   . LEU C 2 135 ? 128.733 152.708 84.570  1.00 47.50  ? 81  LEU B C   1 
ATOM   6056  O  O   . LEU C 2 135 ? 129.782 152.133 84.865  1.00 52.79  ? 81  LEU B O   1 
ATOM   6057  C  CB  . LEU C 2 135 ? 129.004 152.743 82.086  1.00 44.56  ? 81  LEU B CB  1 
ATOM   6058  C  CG  . LEU C 2 135 ? 128.981 153.492 80.758  1.00 48.76  ? 81  LEU B CG  1 
ATOM   6059  C  CD1 . LEU C 2 135 ? 129.223 152.540 79.610  1.00 48.80  ? 81  LEU B CD1 1 
ATOM   6060  C  CD2 . LEU C 2 135 ? 127.667 154.212 80.592  1.00 52.11  ? 81  LEU B CD2 1 
ATOM   6061  N  N   . THR C 2 136 ? 127.628 152.609 85.297  1.00 43.86  ? 82  THR B N   1 
ATOM   6062  C  CA  . THR C 2 136 ? 127.520 151.684 86.419  1.00 45.97  ? 82  THR B CA  1 
ATOM   6063  C  C   . THR C 2 136 ? 127.013 150.358 85.877  1.00 46.86  ? 82  THR B C   1 
ATOM   6064  O  O   . THR C 2 136 ? 125.874 150.269 85.412  1.00 45.86  ? 82  THR B O   1 
ATOM   6065  C  CB  . THR C 2 136 ? 126.580 152.224 87.491  1.00 49.07  ? 82  THR B CB  1 
ATOM   6066  O  OG1 . THR C 2 136 ? 127.086 153.465 87.992  1.00 55.29  ? 82  THR B OG1 1 
ATOM   6067  C  CG2 . THR C 2 136 ? 126.475 151.241 88.631  1.00 47.98  ? 82  THR B CG2 1 
ATOM   6068  N  N   . LEU C 2 137 ? 127.850 149.327 85.924  1.00 46.92  ? 83  LEU B N   1 
ATOM   6069  C  CA  . LEU C 2 137 ? 127.462 148.054 85.337  1.00 43.26  ? 83  LEU B CA  1 
ATOM   6070  C  C   . LEU C 2 137 ? 127.036 147.071 86.417  1.00 46.24  ? 83  LEU B C   1 
ATOM   6071  O  O   . LEU C 2 137 ? 127.392 147.204 87.589  1.00 48.55  ? 83  LEU B O   1 
ATOM   6072  C  CB  . LEU C 2 137 ? 128.602 147.468 84.507  1.00 41.61  ? 83  LEU B CB  1 
ATOM   6073  C  CG  . LEU C 2 137 ? 128.956 148.219 83.226  1.00 42.79  ? 83  LEU B CG  1 
ATOM   6074  C  CD1 . LEU C 2 137 ? 130.026 147.470 82.466  1.00 39.33  ? 83  LEU B CD1 1 
ATOM   6075  C  CD2 . LEU C 2 137 ? 127.726 148.424 82.364  1.00 41.43  ? 83  LEU B CD2 1 
ATOM   6076  N  N   . ASP C 2 138 ? 126.249 146.082 86.005  1.00 42.13  ? 84  ASP B N   1 
ATOM   6077  C  CA  . ASP C 2 138 ? 125.837 145.034 86.925  1.00 42.82  ? 84  ASP B CA  1 
ATOM   6078  C  C   . ASP C 2 138 ? 127.060 144.282 87.427  1.00 46.27  ? 84  ASP B C   1 
ATOM   6079  O  O   . ASP C 2 138 ? 127.983 143.994 86.665  1.00 47.49  ? 84  ASP B O   1 
ATOM   6080  C  CB  . ASP C 2 138 ? 124.867 144.076 86.241  1.00 42.78  ? 84  ASP B CB  1 
ATOM   6081  C  CG  . ASP C 2 138 ? 124.106 143.216 87.227  1.00 52.42  ? 84  ASP B CG  1 
ATOM   6082  O  OD1 . ASP C 2 138 ? 124.185 143.489 88.442  1.00 58.51  ? 84  ASP B OD1 1 
ATOM   6083  O  OD2 . ASP C 2 138 ? 123.428 142.265 86.793  1.00 52.78  ? 84  ASP B OD2 1 
ATOM   6084  N  N   . ASN C 2 139 ? 127.058 143.952 88.720  1.00 46.42  ? 85  ASN B N   1 
ATOM   6085  C  CA  . ASN C 2 139 ? 128.266 143.450 89.363  1.00 44.99  ? 85  ASN B CA  1 
ATOM   6086  C  C   . ASN C 2 139 ? 128.763 142.146 88.754  1.00 46.38  ? 85  ASN B C   1 
ATOM   6087  O  O   . ASN C 2 139 ? 129.939 141.808 88.925  1.00 50.20  ? 85  ASN B O   1 
ATOM   6088  C  CB  . ASN C 2 139 ? 128.034 143.281 90.865  1.00 42.76  ? 85  ASN B CB  1 
ATOM   6089  C  CG  . ASN C 2 139 ? 126.954 142.278 91.187  1.00 45.55  ? 85  ASN B CG  1 
ATOM   6090  O  OD1 . ASN C 2 139 ? 127.226 141.223 91.754  1.00 45.57  ? 85  ASN B OD1 1 
ATOM   6091  N  ND2 . ASN C 2 139 ? 125.719 142.605 90.845  1.00 46.95  ? 85  ASN B ND2 1 
ATOM   6092  N  N   . ARG C 2 140 ? 127.910 141.414 88.036  1.00 44.75  ? 86  ARG B N   1 
ATOM   6093  C  CA  . ARG C 2 140 ? 128.363 140.190 87.387  1.00 45.55  ? 86  ARG B CA  1 
ATOM   6094  C  C   . ARG C 2 140 ? 129.436 140.473 86.342  1.00 47.06  ? 86  ARG B C   1 
ATOM   6095  O  O   . ARG C 2 140 ? 130.296 139.621 86.090  1.00 48.85  ? 86  ARG B O   1 
ATOM   6096  C  CB  . ARG C 2 140 ? 127.172 139.460 86.770  1.00 47.18  ? 86  ARG B CB  1 
ATOM   6097  C  CG  . ARG C 2 140 ? 126.307 138.750 87.798  1.00 47.96  ? 86  ARG B CG  1 
ATOM   6098  C  CD  . ARG C 2 140 ? 125.024 138.203 87.203  1.00 47.75  ? 86  ARG B CD  1 
ATOM   6099  N  NE  . ARG C 2 140 ? 124.027 139.249 87.017  1.00 53.45  ? 86  ARG B NE  1 
ATOM   6100  C  CZ  . ARG C 2 140 ? 122.736 139.029 86.818  1.00 54.79  ? 86  ARG B CZ  1 
ATOM   6101  N  NH1 . ARG C 2 140 ? 122.242 137.805 86.773  1.00 56.49  ? 86  ARG B NH1 1 
ATOM   6102  N  NH2 . ARG C 2 140 ? 121.916 140.066 86.678  1.00 52.64  ? 86  ARG B NH2 1 
ATOM   6103  N  N   . VAL C 2 141 ? 129.432 141.673 85.757  1.00 45.09  ? 87  VAL B N   1 
ATOM   6104  C  CA  . VAL C 2 141 ? 130.467 142.046 84.802  1.00 42.38  ? 87  VAL B CA  1 
ATOM   6105  C  C   . VAL C 2 141 ? 131.844 142.007 85.439  1.00 45.93  ? 87  VAL B C   1 
ATOM   6106  O  O   . VAL C 2 141 ? 132.851 141.924 84.730  1.00 48.45  ? 87  VAL B O   1 
ATOM   6107  C  CB  . VAL C 2 141 ? 130.188 143.441 84.208  1.00 40.02  ? 87  VAL B CB  1 
ATOM   6108  C  CG1 . VAL C 2 141 ? 130.675 144.522 85.138  1.00 39.53  ? 87  VAL B CG1 1 
ATOM   6109  C  CG2 . VAL C 2 141 ? 130.846 143.583 82.852  1.00 41.80  ? 87  VAL B CG2 1 
ATOM   6110  N  N   . ALA C 2 142 ? 131.916 142.045 86.771  1.00 45.91  ? 88  ALA B N   1 
ATOM   6111  C  CA  . ALA C 2 142 ? 133.204 141.971 87.445  1.00 44.97  ? 88  ALA B CA  1 
ATOM   6112  C  C   . ALA C 2 142 ? 133.913 140.655 87.174  1.00 47.22  ? 88  ALA B C   1 
ATOM   6113  O  O   . ALA C 2 142 ? 135.126 140.565 87.377  1.00 47.93  ? 88  ALA B O   1 
ATOM   6114  C  CB  . ALA C 2 142 ? 133.023 142.172 88.947  1.00 42.34  ? 88  ALA B CB  1 
ATOM   6115  N  N   . ASP C 2 143 ? 133.187 139.634 86.723  1.00 48.62  ? 89  ASP B N   1 
ATOM   6116  C  CA  . ASP C 2 143 ? 133.819 138.368 86.382  1.00 50.49  ? 89  ASP B CA  1 
ATOM   6117  C  C   . ASP C 2 143 ? 134.467 138.374 85.006  1.00 47.62  ? 89  ASP B C   1 
ATOM   6118  O  O   . ASP C 2 143 ? 135.168 137.417 84.670  1.00 50.23  ? 89  ASP B O   1 
ATOM   6119  C  CB  . ASP C 2 143 ? 132.795 137.238 86.450  1.00 53.56  ? 89  ASP B CB  1 
ATOM   6120  C  CG  . ASP C 2 143 ? 132.128 137.148 87.795  1.00 60.86  ? 89  ASP B CG  1 
ATOM   6121  O  OD1 . ASP C 2 143 ? 132.747 137.565 88.792  1.00 58.13  ? 89  ASP B OD1 1 
ATOM   6122  O  OD2 . ASP C 2 143 ? 130.982 136.662 87.856  1.00 67.04  ? 89  ASP B OD2 1 
ATOM   6123  N  N   . GLN C 2 144 ? 134.241 139.408 84.200  1.00 44.25  ? 90  GLN B N   1 
ATOM   6124  C  CA  . GLN C 2 144 ? 134.836 139.497 82.875  1.00 44.98  ? 90  GLN B CA  1 
ATOM   6125  C  C   . GLN C 2 144 ? 135.932 140.546 82.800  1.00 46.24  ? 90  GLN B C   1 
ATOM   6126  O  O   . GLN C 2 144 ? 136.438 140.822 81.711  1.00 47.35  ? 90  GLN B O   1 
ATOM   6127  C  CB  . GLN C 2 144 ? 133.761 139.797 81.833  1.00 46.40  ? 90  GLN B CB  1 
ATOM   6128  C  CG  . GLN C 2 144 ? 132.591 138.840 81.854  1.00 50.40  ? 90  GLN B CG  1 
ATOM   6129  C  CD  . GLN C 2 144 ? 131.480 139.271 80.928  1.00 62.17  ? 90  GLN B CD  1 
ATOM   6130  O  OE1 . GLN C 2 144 ? 130.653 140.111 81.280  1.00 59.70  ? 90  GLN B OE1 1 
ATOM   6131  N  NE2 . GLN C 2 144 ? 131.456 138.700 79.732  1.00 69.14  ? 90  GLN B NE2 1 
ATOM   6132  N  N   . LEU C 2 145 ? 136.312 141.132 83.928  1.00 45.63  ? 91  LEU B N   1 
ATOM   6133  C  CA  . LEU C 2 145 ? 137.298 142.196 83.972  1.00 42.13  ? 91  LEU B CA  1 
ATOM   6134  C  C   . LEU C 2 145 ? 138.460 141.787 84.859  1.00 40.90  ? 91  LEU B C   1 
ATOM   6135  O  O   . LEU C 2 145 ? 138.311 140.967 85.766  1.00 42.40  ? 91  LEU B O   1 
ATOM   6136  C  CB  . LEU C 2 145 ? 136.689 143.493 84.498  1.00 37.68  ? 91  LEU B CB  1 
ATOM   6137  C  CG  . LEU C 2 145 ? 135.622 144.141 83.629  1.00 38.33  ? 91  LEU B CG  1 
ATOM   6138  C  CD1 . LEU C 2 145 ? 135.197 145.455 84.232  1.00 37.39  ? 91  LEU B CD1 1 
ATOM   6139  C  CD2 . LEU C 2 145 ? 136.156 144.339 82.234  1.00 37.59  ? 91  LEU B CD2 1 
ATOM   6140  N  N   . TRP C 2 146 ? 139.627 142.355 84.577  1.00 38.16  ? 92  TRP B N   1 
ATOM   6141  C  CA  . TRP C 2 146 ? 140.770 142.176 85.455  1.00 35.03  ? 92  TRP B CA  1 
ATOM   6142  C  C   . TRP C 2 146 ? 140.582 142.995 86.724  1.00 37.14  ? 92  TRP B C   1 
ATOM   6143  O  O   . TRP C 2 146 ? 140.140 144.144 86.676  1.00 40.39  ? 92  TRP B O   1 
ATOM   6144  C  CB  . TRP C 2 146 ? 142.053 142.591 84.740  1.00 35.21  ? 92  TRP B CB  1 
ATOM   6145  C  CG  . TRP C 2 146 ? 143.286 142.422 85.558  1.00 37.81  ? 92  TRP B CG  1 
ATOM   6146  C  CD1 . TRP C 2 146 ? 144.096 141.332 85.597  1.00 36.73  ? 92  TRP B CD1 1 
ATOM   6147  C  CD2 . TRP C 2 146 ? 143.855 143.377 86.461  1.00 37.98  ? 92  TRP B CD2 1 
ATOM   6148  N  NE1 . TRP C 2 146 ? 145.133 141.543 86.470  1.00 37.38  ? 92  TRP B NE1 1 
ATOM   6149  C  CE2 . TRP C 2 146 ? 145.008 142.795 87.009  1.00 38.51  ? 92  TRP B CE2 1 
ATOM   6150  C  CE3 . TRP C 2 146 ? 143.500 144.667 86.856  1.00 34.95  ? 92  TRP B CE3 1 
ATOM   6151  C  CZ2 . TRP C 2 146 ? 145.805 143.457 87.933  1.00 39.82  ? 92  TRP B CZ2 1 
ATOM   6152  C  CZ3 . TRP C 2 146 ? 144.294 145.319 87.771  1.00 32.13  ? 92  TRP B CZ3 1 
ATOM   6153  C  CH2 . TRP C 2 146 ? 145.431 144.718 88.296  1.00 36.79  ? 92  TRP B CH2 1 
ATOM   6154  N  N   . VAL C 2 147 ? 140.894 142.391 87.866  1.00 36.27  ? 93  VAL B N   1 
ATOM   6155  C  CA  . VAL C 2 147 ? 140.868 143.101 89.142  1.00 32.23  ? 93  VAL B CA  1 
ATOM   6156  C  C   . VAL C 2 147 ? 142.149 142.776 89.899  1.00 32.59  ? 93  VAL B C   1 
ATOM   6157  O  O   . VAL C 2 147 ? 142.748 141.718 89.668  1.00 32.24  ? 93  VAL B O   1 
ATOM   6158  C  CB  . VAL C 2 147 ? 139.620 142.746 89.967  1.00 28.93  ? 93  VAL B CB  1 
ATOM   6159  C  CG1 . VAL C 2 147 ? 138.368 143.255 89.281  1.00 29.35  ? 93  VAL B CG1 1 
ATOM   6160  C  CG2 . VAL C 2 147 ? 139.535 141.261 90.197  1.00 29.64  ? 93  VAL B CG2 1 
ATOM   6161  N  N   . PRO C 2 148 ? 142.620 143.657 90.778  1.00 31.96  ? 94  PRO B N   1 
ATOM   6162  C  CA  . PRO C 2 148 ? 143.827 143.352 91.551  1.00 31.96  ? 94  PRO B CA  1 
ATOM   6163  C  C   . PRO C 2 148 ? 143.628 142.156 92.468  1.00 33.04  ? 94  PRO B C   1 
ATOM   6164  O  O   . PRO C 2 148 ? 142.540 141.919 92.994  1.00 32.00  ? 94  PRO B O   1 
ATOM   6165  C  CB  . PRO C 2 148 ? 144.062 144.632 92.355  1.00 31.52  ? 94  PRO B CB  1 
ATOM   6166  C  CG  . PRO C 2 148 ? 143.374 145.684 91.598  1.00 29.22  ? 94  PRO B CG  1 
ATOM   6167  C  CD  . PRO C 2 148 ? 142.183 145.047 90.975  1.00 29.93  ? 94  PRO B CD  1 
ATOM   6168  N  N   . ASP C 2 149 ? 144.706 141.404 92.662  1.00 35.20  ? 95  ASP B N   1 
ATOM   6169  C  CA  . ASP C 2 149 ? 144.706 140.242 93.547  1.00 32.50  ? 95  ASP B CA  1 
ATOM   6170  C  C   . ASP C 2 149 ? 145.029 140.638 94.984  1.00 32.22  ? 95  ASP B C   1 
ATOM   6171  O  O   . ASP C 2 149 ? 145.872 140.044 95.646  1.00 34.33  ? 95  ASP B O   1 
ATOM   6172  C  CB  . ASP C 2 149 ? 145.694 139.208 93.028  1.00 37.19  ? 95  ASP B CB  1 
ATOM   6173  C  CG  . ASP C 2 149 ? 147.108 139.730 92.994  1.00 43.14  ? 95  ASP B CG  1 
ATOM   6174  O  OD1 . ASP C 2 149 ? 147.284 140.964 92.989  1.00 38.92  ? 95  ASP B OD1 1 
ATOM   6175  O  OD2 . ASP C 2 149 ? 148.044 138.908 92.976  1.00 48.73  ? 95  ASP B OD2 1 
ATOM   6176  N  N   . THR C 2 150 ? 144.327 141.652 95.472  1.00 30.71  ? 96  THR B N   1 
ATOM   6177  C  CA  . THR C 2 150 ? 144.559 142.172 96.809  1.00 28.56  ? 96  THR B CA  1 
ATOM   6178  C  C   . THR C 2 150 ? 144.126 141.164 97.866  1.00 28.86  ? 96  THR B C   1 
ATOM   6179  O  O   . THR C 2 150 ? 143.093 140.507 97.732  1.00 35.05  ? 96  THR B O   1 
ATOM   6180  C  CB  . THR C 2 150 ? 143.795 143.479 96.978  1.00 29.19  ? 96  THR B CB  1 
ATOM   6181  O  OG1 . THR C 2 150 ? 144.327 144.460 96.083  1.00 32.79  ? 96  THR B OG1 1 
ATOM   6182  C  CG2 . THR C 2 150 ? 143.898 143.987 98.387  1.00 31.59  ? 96  THR B CG2 1 
ATOM   6183  N  N   . TYR C 2 151 ? 144.925 141.030 98.921  1.00 25.89  ? 97  TYR B N   1 
ATOM   6184  C  CA  . TYR C 2 151 ? 144.583 140.144 100.020 1.00 26.25  ? 97  TYR B CA  1 
ATOM   6185  C  C   . TYR C 2 151 ? 145.004 140.791 101.328 1.00 27.83  ? 97  TYR B C   1 
ATOM   6186  O  O   . TYR C 2 151 ? 145.721 141.792 101.352 1.00 30.56  ? 97  TYR B O   1 
ATOM   6187  C  CB  . TYR C 2 151 ? 145.222 138.759 99.853  1.00 27.46  ? 97  TYR B CB  1 
ATOM   6188  C  CG  . TYR C 2 151 ? 146.675 138.667 100.244 1.00 27.75  ? 97  TYR B CG  1 
ATOM   6189  C  CD1 . TYR C 2 151 ? 147.672 139.020 99.359  1.00 29.56  ? 97  TYR B CD1 1 
ATOM   6190  C  CD2 . TYR C 2 151 ? 147.049 138.193 101.486 1.00 29.05  ? 97  TYR B CD2 1 
ATOM   6191  C  CE1 . TYR C 2 151 ? 148.992 138.932 99.709  1.00 29.10  ? 97  TYR B CE1 1 
ATOM   6192  C  CE2 . TYR C 2 151 ? 148.369 138.101 101.840 1.00 30.28  ? 97  TYR B CE2 1 
ATOM   6193  C  CZ  . TYR C 2 151 ? 149.334 138.476 100.948 1.00 29.86  ? 97  TYR B CZ  1 
ATOM   6194  O  OH  . TYR C 2 151 ? 150.652 138.385 101.298 1.00 34.06  ? 97  TYR B OH  1 
ATOM   6195  N  N   . PHE C 2 152 ? 144.517 140.230 102.426 1.00 30.43  ? 98  PHE B N   1 
ATOM   6196  C  CA  . PHE C 2 152 ? 144.867 140.687 103.762 1.00 30.24  ? 98  PHE B CA  1 
ATOM   6197  C  C   . PHE C 2 152 ? 145.729 139.624 104.418 1.00 31.52  ? 98  PHE B C   1 
ATOM   6198  O  O   . PHE C 2 152 ? 145.337 138.457 104.482 1.00 36.96  ? 98  PHE B O   1 
ATOM   6199  C  CB  . PHE C 2 152 ? 143.618 140.965 104.597 1.00 27.83  ? 98  PHE B CB  1 
ATOM   6200  C  CG  . PHE C 2 152 ? 142.591 141.782 103.883 1.00 31.56  ? 98  PHE B CG  1 
ATOM   6201  C  CD1 . PHE C 2 152 ? 142.857 143.082 103.513 1.00 31.61  ? 98  PHE B CD1 1 
ATOM   6202  C  CD2 . PHE C 2 152 ? 141.358 141.252 103.577 1.00 32.92  ? 98  PHE B CD2 1 
ATOM   6203  C  CE1 . PHE C 2 152 ? 141.918 143.830 102.850 1.00 28.55  ? 98  PHE B CE1 1 
ATOM   6204  C  CE2 . PHE C 2 152 ? 140.418 142.001 102.913 1.00 30.95  ? 98  PHE B CE2 1 
ATOM   6205  C  CZ  . PHE C 2 152 ? 140.700 143.288 102.552 1.00 27.25  ? 98  PHE B CZ  1 
ATOM   6206  N  N   . LEU C 2 153 ? 146.904 140.025 104.897 1.00 28.90  ? 99  LEU B N   1 
ATOM   6207  C  CA  . LEU C 2 153 ? 147.881 139.040 105.341 1.00 29.77  ? 99  LEU B CA  1 
ATOM   6208  C  C   . LEU C 2 153 ? 147.497 138.425 106.679 1.00 33.35  ? 99  LEU B C   1 
ATOM   6209  O  O   . LEU C 2 153 ? 147.745 137.239 106.911 1.00 38.16  ? 99  LEU B O   1 
ATOM   6210  C  CB  . LEU C 2 153 ? 149.267 139.676 105.411 1.00 33.50  ? 99  LEU B CB  1 
ATOM   6211  C  CG  . LEU C 2 153 ? 150.403 138.789 105.916 1.00 34.61  ? 99  LEU B CG  1 
ATOM   6212  C  CD1 . LEU C 2 153 ? 150.485 137.504 105.137 1.00 31.02  ? 99  LEU B CD1 1 
ATOM   6213  C  CD2 . LEU C 2 153 ? 151.707 139.524 105.830 1.00 40.27  ? 99  LEU B CD2 1 
ATOM   6214  N  N   . ASN C 2 154 ? 146.890 139.201 107.571 1.00 31.35  ? 100 ASN B N   1 
ATOM   6215  C  CA  . ASN C 2 154 ? 146.613 138.726 108.918 1.00 29.05  ? 100 ASN B CA  1 
ATOM   6216  C  C   . ASN C 2 154 ? 145.164 138.314 109.132 1.00 29.68  ? 100 ASN B C   1 
ATOM   6217  O  O   . ASN C 2 154 ? 144.768 138.081 110.275 1.00 32.38  ? 100 ASN B O   1 
ATOM   6218  C  CB  . ASN C 2 154 ? 147.006 139.783 109.948 1.00 28.36  ? 100 ASN B CB  1 
ATOM   6219  C  CG  . ASN C 2 154 ? 146.319 141.092 109.719 1.00 31.07  ? 100 ASN B CG  1 
ATOM   6220  O  OD1 . ASN C 2 154 ? 146.139 141.514 108.586 1.00 34.28  ? 100 ASN B OD1 1 
ATOM   6221  N  ND2 . ASN C 2 154 ? 145.930 141.750 110.794 1.00 30.51  ? 100 ASN B ND2 1 
ATOM   6222  N  N   . ASP C 2 155 ? 144.364 138.213 108.078 1.00 29.48  ? 101 ASP B N   1 
ATOM   6223  C  CA  . ASP C 2 155 ? 142.994 137.762 108.253 1.00 31.28  ? 101 ASP B CA  1 
ATOM   6224  C  C   . ASP C 2 155 ? 142.952 136.246 108.390 1.00 31.91  ? 101 ASP B C   1 
ATOM   6225  O  O   . ASP C 2 155 ? 143.807 135.530 107.868 1.00 37.32  ? 101 ASP B O   1 
ATOM   6226  C  CB  . ASP C 2 155 ? 142.113 138.214 107.092 1.00 31.44  ? 101 ASP B CB  1 
ATOM   6227  C  CG  . ASP C 2 155 ? 142.168 137.272 105.917 1.00 37.84  ? 101 ASP B CG  1 
ATOM   6228  O  OD1 . ASP C 2 155 ? 143.276 136.858 105.532 1.00 47.10  ? 101 ASP B OD1 1 
ATOM   6229  O  OD2 . ASP C 2 155 ? 141.097 136.944 105.371 1.00 37.58  ? 101 ASP B OD2 1 
ATOM   6230  N  N   . LYS C 2 156 ? 141.953 135.761 109.114 1.00 30.69  ? 102 LYS B N   1 
ATOM   6231  C  CA  . LYS C 2 156 ? 141.807 134.345 109.391 1.00 28.46  ? 102 LYS B CA  1 
ATOM   6232  C  C   . LYS C 2 156 ? 140.565 133.745 108.771 1.00 30.37  ? 102 LYS B C   1 
ATOM   6233  O  O   . LYS C 2 156 ? 140.554 132.552 108.472 1.00 35.71  ? 102 LYS B O   1 
ATOM   6234  C  CB  . LYS C 2 156 ? 141.777 134.112 110.907 1.00 27.52  ? 102 LYS B CB  1 
ATOM   6235  C  CG  . LYS C 2 156 ? 142.756 134.993 111.651 1.00 29.74  ? 102 LYS B CG  1 
ATOM   6236  C  CD  . LYS C 2 156 ? 142.406 135.135 113.112 1.00 31.42  ? 102 LYS B CD  1 
ATOM   6237  C  CE  . LYS C 2 156 ? 142.589 133.842 113.857 1.00 33.72  ? 102 LYS B CE  1 
ATOM   6238  N  NZ  . LYS C 2 156 ? 142.187 133.978 115.275 1.00 34.24  ? 102 LYS B NZ  1 
ATOM   6239  N  N   . LYS C 2 157 ? 139.528 134.545 108.558 1.00 30.44  ? 103 LYS B N   1 
ATOM   6240  C  CA  . LYS C 2 157 ? 138.277 134.073 107.982 1.00 32.72  ? 103 LYS B CA  1 
ATOM   6241  C  C   . LYS C 2 157 ? 137.529 135.291 107.474 1.00 33.09  ? 103 LYS B C   1 
ATOM   6242  O  O   . LYS C 2 157 ? 137.149 136.150 108.271 1.00 36.51  ? 103 LYS B O   1 
ATOM   6243  C  CB  . LYS C 2 157 ? 137.465 133.321 109.029 1.00 34.78  ? 103 LYS B CB  1 
ATOM   6244  C  CG  . LYS C 2 157 ? 136.147 132.779 108.545 1.00 38.40  ? 103 LYS B CG  1 
ATOM   6245  C  CD  . LYS C 2 157 ? 135.418 132.096 109.678 1.00 48.98  ? 103 LYS B CD  1 
ATOM   6246  C  CE  . LYS C 2 157 ? 135.423 132.965 110.923 1.00 50.91  ? 103 LYS B CE  1 
ATOM   6247  N  NZ  . LYS C 2 157 ? 134.652 132.359 112.039 1.00 60.18  ? 103 LYS B NZ  1 
ATOM   6248  N  N   . SER C 2 158 ? 137.326 135.377 106.162 1.00 27.70  ? 104 SER B N   1 
ATOM   6249  C  CA  . SER C 2 158 ? 136.687 136.535 105.554 1.00 25.87  ? 104 SER B CA  1 
ATOM   6250  C  C   . SER C 2 158 ? 135.654 136.074 104.541 1.00 30.00  ? 104 SER B C   1 
ATOM   6251  O  O   . SER C 2 158 ? 135.722 134.960 104.021 1.00 41.33  ? 104 SER B O   1 
ATOM   6252  C  CB  . SER C 2 158 ? 137.700 137.449 104.865 1.00 28.61  ? 104 SER B CB  1 
ATOM   6253  O  OG  . SER C 2 158 ? 138.791 137.738 105.713 1.00 37.11  ? 104 SER B OG  1 
ATOM   6254  N  N   . PHE C 2 159 ? 134.690 136.946 104.262 1.00 28.48  ? 105 PHE B N   1 
ATOM   6255  C  CA  . PHE C 2 159 ? 133.678 136.639 103.265 1.00 27.70  ? 105 PHE B CA  1 
ATOM   6256  C  C   . PHE C 2 159 ? 133.085 137.932 102.729 1.00 27.41  ? 105 PHE B C   1 
ATOM   6257  O  O   . PHE C 2 159 ? 133.060 138.950 103.418 1.00 29.14  ? 105 PHE B O   1 
ATOM   6258  C  CB  . PHE C 2 159 ? 132.579 135.743 103.843 1.00 25.50  ? 105 PHE B CB  1 
ATOM   6259  C  CG  . PHE C 2 159 ? 131.744 136.401 104.902 1.00 26.69  ? 105 PHE B CG  1 
ATOM   6260  C  CD1 . PHE C 2 159 ? 132.134 136.381 106.223 1.00 27.66  ? 105 PHE B CD1 1 
ATOM   6261  C  CD2 . PHE C 2 159 ? 130.561 137.030 104.578 1.00 25.51  ? 105 PHE B CD2 1 
ATOM   6262  C  CE1 . PHE C 2 159 ? 131.362 136.979 107.190 1.00 26.89  ? 105 PHE B CE1 1 
ATOM   6263  C  CE2 . PHE C 2 159 ? 129.794 137.631 105.544 1.00 26.05  ? 105 PHE B CE2 1 
ATOM   6264  C  CZ  . PHE C 2 159 ? 130.193 137.606 106.847 1.00 25.75  ? 105 PHE B CZ  1 
ATOM   6265  N  N   . VAL C 2 160 ? 132.611 137.874 101.493 1.00 25.73  ? 106 VAL B N   1 
ATOM   6266  C  CA  . VAL C 2 160 ? 131.877 138.973 100.883 1.00 25.37  ? 106 VAL B CA  1 
ATOM   6267  C  C   . VAL C 2 160 ? 130.392 138.709 101.070 1.00 31.46  ? 106 VAL B C   1 
ATOM   6268  O  O   . VAL C 2 160 ? 129.918 137.595 100.824 1.00 38.91  ? 106 VAL B O   1 
ATOM   6269  C  CB  . VAL C 2 160 ? 132.228 139.118 99.394  1.00 23.90  ? 106 VAL B CB  1 
ATOM   6270  C  CG1 . VAL C 2 160 ? 131.453 140.253 98.782  1.00 24.30  ? 106 VAL B CG1 1 
ATOM   6271  C  CG2 . VAL C 2 160 ? 133.695 139.359 99.218  1.00 26.54  ? 106 VAL B CG2 1 
ATOM   6272  N  N   . HIS C 2 161 ? 129.660 139.720 101.527 1.00 26.53  ? 107 HIS B N   1 
ATOM   6273  C  CA  . HIS C 2 161 ? 128.234 139.556 101.762 1.00 27.91  ? 107 HIS B CA  1 
ATOM   6274  C  C   . HIS C 2 161 ? 127.501 139.277 100.455 1.00 32.95  ? 107 HIS B C   1 
ATOM   6275  O  O   . HIS C 2 161 ? 127.767 139.908 99.432  1.00 32.17  ? 107 HIS B O   1 
ATOM   6276  C  CB  . HIS C 2 161 ? 127.675 140.807 102.436 1.00 26.19  ? 107 HIS B CB  1 
ATOM   6277  C  CG  . HIS C 2 161 ? 128.263 141.079 103.785 1.00 27.42  ? 107 HIS B CG  1 
ATOM   6278  N  ND1 . HIS C 2 161 ? 127.510 141.093 104.936 1.00 29.50  ? 107 HIS B ND1 1 
ATOM   6279  C  CD2 . HIS C 2 161 ? 129.533 141.342 104.165 1.00 27.70  ? 107 HIS B CD2 1 
ATOM   6280  C  CE1 . HIS C 2 161 ? 128.290 141.351 105.968 1.00 25.84  ? 107 HIS B CE1 1 
ATOM   6281  N  NE2 . HIS C 2 161 ? 129.523 141.506 105.527 1.00 25.84  ? 107 HIS B NE2 1 
ATOM   6282  N  N   . GLY C 2 162 ? 126.561 138.333 100.492 1.00 31.95  ? 108 GLY B N   1 
ATOM   6283  C  CA  . GLY C 2 162 ? 125.909 137.887 99.275  1.00 30.44  ? 108 GLY B CA  1 
ATOM   6284  C  C   . GLY C 2 162 ? 124.393 137.873 99.273  1.00 31.79  ? 108 GLY B C   1 
ATOM   6285  O  O   . GLY C 2 162 ? 123.786 137.062 98.572  1.00 33.65  ? 108 GLY B O   1 
ATOM   6286  N  N   . VAL C 2 163 ? 123.767 138.761 100.039 1.00 30.68  ? 109 VAL B N   1 
ATOM   6287  C  CA  . VAL C 2 163 ? 122.320 138.942 100.032 1.00 25.82  ? 109 VAL B CA  1 
ATOM   6288  C  C   . VAL C 2 163 ? 122.038 140.407 99.733  1.00 26.81  ? 109 VAL B C   1 
ATOM   6289  O  O   . VAL C 2 163 ? 122.597 141.291 100.392 1.00 29.45  ? 109 VAL B O   1 
ATOM   6290  C  CB  . VAL C 2 163 ? 121.686 138.518 101.370 1.00 21.98  ? 109 VAL B CB  1 
ATOM   6291  C  CG1 . VAL C 2 163 ? 120.224 138.870 101.405 1.00 22.14  ? 109 VAL B CG1 1 
ATOM   6292  C  CG2 . VAL C 2 163 ? 121.853 137.042 101.580 1.00 23.64  ? 109 VAL B CG2 1 
ATOM   6293  N  N   . THR C 2 164 ? 121.184 140.673 98.744  1.00 25.41  ? 110 THR B N   1 
ATOM   6294  C  CA  . THR C 2 164 ? 120.495 139.656 97.955  1.00 26.10  ? 110 THR B CA  1 
ATOM   6295  C  C   . THR C 2 164 ? 121.334 139.197 96.771  1.00 28.02  ? 110 THR B C   1 
ATOM   6296  O  O   . THR C 2 164 ? 121.085 138.143 96.199  1.00 31.26  ? 110 THR B O   1 
ATOM   6297  C  CB  . THR C 2 164 ? 119.143 140.172 97.440  1.00 23.62  ? 110 THR B CB  1 
ATOM   6298  O  OG1 . THR C 2 164 ? 119.358 141.119 96.391  1.00 29.83  ? 110 THR B OG1 1 
ATOM   6299  C  CG2 . THR C 2 164 ? 118.380 140.849 98.546  1.00 18.82  ? 110 THR B CG2 1 
ATOM   6300  N  N   . VAL C 2 165 ? 122.322 140.010 96.404  1.00 29.37  ? 111 VAL B N   1 
ATOM   6301  C  CA  . VAL C 2 165 ? 123.336 139.643 95.426  1.00 31.99  ? 111 VAL B CA  1 
ATOM   6302  C  C   . VAL C 2 165 ? 124.688 139.953 96.044  1.00 33.72  ? 111 VAL B C   1 
ATOM   6303  O  O   . VAL C 2 165 ? 124.787 140.681 97.032  1.00 36.28  ? 111 VAL B O   1 
ATOM   6304  C  CB  . VAL C 2 165 ? 123.177 140.386 94.082  1.00 31.76  ? 111 VAL B CB  1 
ATOM   6305  C  CG1 . VAL C 2 165 ? 121.858 140.041 93.432  1.00 33.73  ? 111 VAL B CG1 1 
ATOM   6306  C  CG2 . VAL C 2 165 ? 123.286 141.875 94.285  1.00 30.36  ? 111 VAL B CG2 1 
ATOM   6307  N  N   . LYS C 2 166 ? 125.736 139.381 95.463  1.00 32.16  ? 112 LYS B N   1 
ATOM   6308  C  CA  . LYS C 2 166 ? 127.078 139.627 95.969  1.00 32.56  ? 112 LYS B CA  1 
ATOM   6309  C  C   . LYS C 2 166 ? 127.345 141.125 96.009  1.00 33.44  ? 112 LYS B C   1 
ATOM   6310  O  O   . LYS C 2 166 ? 127.217 141.812 94.995  1.00 35.71  ? 112 LYS B O   1 
ATOM   6311  C  CB  . LYS C 2 166 ? 128.111 138.915 95.101  1.00 34.43  ? 112 LYS B CB  1 
ATOM   6312  C  CG  . LYS C 2 166 ? 129.506 138.987 95.671  1.00 39.60  ? 112 LYS B CG  1 
ATOM   6313  C  CD  . LYS C 2 166 ? 130.518 138.214 94.861  1.00 43.98  ? 112 LYS B CD  1 
ATOM   6314  C  CE  . LYS C 2 166 ? 131.914 138.460 95.415  1.00 52.62  ? 112 LYS B CE  1 
ATOM   6315  N  NZ  . LYS C 2 166 ? 132.991 137.844 94.593  1.00 58.52  ? 112 LYS B NZ  1 
ATOM   6316  N  N   . ASN C 2 167 ? 127.700 141.637 97.188  1.00 29.91  ? 113 ASN B N   1 
ATOM   6317  C  CA  . ASN C 2 167 ? 127.769 143.080 97.414  1.00 28.62  ? 113 ASN B CA  1 
ATOM   6318  C  C   . ASN C 2 167 ? 129.009 143.615 96.706  1.00 32.86  ? 113 ASN B C   1 
ATOM   6319  O  O   . ASN C 2 167 ? 130.067 143.832 97.297  1.00 32.77  ? 113 ASN B O   1 
ATOM   6320  C  CB  . ASN C 2 167 ? 127.788 143.405 98.901  1.00 27.06  ? 113 ASN B CB  1 
ATOM   6321  C  CG  . ASN C 2 167 ? 126.509 143.004 99.606  1.00 27.30  ? 113 ASN B CG  1 
ATOM   6322  O  OD1 . ASN C 2 167 ? 126.403 143.114 100.821 1.00 27.09  ? 113 ASN B OD1 1 
ATOM   6323  N  ND2 . ASN C 2 167 ? 125.537 142.536 98.851  1.00 28.88  ? 113 ASN B ND2 1 
ATOM   6324  N  N   . ARG C 2 168 ? 128.863 143.831 95.405  1.00 35.05  ? 114 ARG B N   1 
ATOM   6325  C  CA  . ARG C 2 168 ? 129.967 144.137 94.515  1.00 32.02  ? 114 ARG B CA  1 
ATOM   6326  C  C   . ARG C 2 168 ? 129.537 145.267 93.595  1.00 35.68  ? 114 ARG B C   1 
ATOM   6327  O  O   . ARG C 2 168 ? 128.375 145.332 93.195  1.00 41.42  ? 114 ARG B O   1 
ATOM   6328  C  CB  . ARG C 2 168 ? 130.354 142.888 93.721  1.00 34.09  ? 114 ARG B CB  1 
ATOM   6329  C  CG  . ARG C 2 168 ? 131.683 142.938 93.032  1.00 38.39  ? 114 ARG B CG  1 
ATOM   6330  C  CD  . ARG C 2 168 ? 132.157 141.535 92.712  1.00 44.75  ? 114 ARG B CD  1 
ATOM   6331  N  NE  . ARG C 2 168 ? 131.199 140.797 91.900  1.00 50.01  ? 114 ARG B NE  1 
ATOM   6332  C  CZ  . ARG C 2 168 ? 131.386 139.558 91.469  1.00 50.69  ? 114 ARG B CZ  1 
ATOM   6333  N  NH1 . ARG C 2 168 ? 132.488 138.888 91.755  1.00 51.63  ? 114 ARG B NH1 1 
ATOM   6334  N  NH2 . ARG C 2 168 ? 130.445 138.976 90.734  1.00 46.85  ? 114 ARG B NH2 1 
ATOM   6335  N  N   . MET C 2 169 ? 130.461 146.168 93.279  1.00 34.19  ? 115 MET B N   1 
ATOM   6336  C  CA  . MET C 2 169 ? 130.135 147.320 92.448  1.00 33.11  ? 115 MET B CA  1 
ATOM   6337  C  C   . MET C 2 169 ? 131.228 147.551 91.419  1.00 37.08  ? 115 MET B C   1 
ATOM   6338  O  O   . MET C 2 169 ? 132.411 147.555 91.768  1.00 39.42  ? 115 MET B O   1 
ATOM   6339  C  CB  . MET C 2 169 ? 129.957 148.583 93.293  1.00 31.72  ? 115 MET B CB  1 
ATOM   6340  C  CG  . MET C 2 169 ? 129.697 149.827 92.470  1.00 42.49  ? 115 MET B CG  1 
ATOM   6341  S  SD  . MET C 2 169 ? 130.673 151.250 92.985  1.00 54.54  ? 115 MET B SD  1 
ATOM   6342  C  CE  . MET C 2 169 ? 130.129 151.434 94.675  1.00 45.06  ? 115 MET B CE  1 
ATOM   6343  N  N   . ILE C 2 170 ? 130.824 147.764 90.167  1.00 37.41  ? 116 ILE B N   1 
ATOM   6344  C  CA  . ILE C 2 170 ? 131.725 148.114 89.075  1.00 37.15  ? 116 ILE B CA  1 
ATOM   6345  C  C   . ILE C 2 170 ? 131.226 149.393 88.417  1.00 42.03  ? 116 ILE B C   1 
ATOM   6346  O  O   . ILE C 2 170 ? 130.080 149.452 87.947  1.00 44.70  ? 116 ILE B O   1 
ATOM   6347  C  CB  . ILE C 2 170 ? 131.840 146.991 88.037  1.00 39.19  ? 116 ILE B CB  1 
ATOM   6348  C  CG1 . ILE C 2 170 ? 132.768 145.902 88.553  1.00 40.84  ? 116 ILE B CG1 1 
ATOM   6349  C  CG2 . ILE C 2 170 ? 132.381 147.530 86.729  1.00 40.81  ? 116 ILE B CG2 1 
ATOM   6350  C  CD1 . ILE C 2 170 ? 134.211 146.314 88.571  1.00 38.02  ? 116 ILE B CD1 1 
ATOM   6351  N  N   . ARG C 2 171 ? 132.088 150.406 88.369  1.00 40.16  ? 117 ARG B N   1 
ATOM   6352  C  CA  . ARG C 2 171 ? 131.782 151.660 87.696  1.00 39.17  ? 117 ARG B CA  1 
ATOM   6353  C  C   . ARG C 2 171 ? 132.918 152.010 86.748  1.00 41.03  ? 117 ARG B C   1 
ATOM   6354  O  O   . ARG C 2 171 ? 134.082 152.043 87.155  1.00 46.13  ? 117 ARG B O   1 
ATOM   6355  C  CB  . ARG C 2 171 ? 131.561 152.782 88.711  1.00 40.36  ? 117 ARG B CB  1 
ATOM   6356  C  CG  . ARG C 2 171 ? 130.997 154.057 88.127  1.00 44.16  ? 117 ARG B CG  1 
ATOM   6357  C  CD  . ARG C 2 171 ? 130.569 155.013 89.222  1.00 45.24  ? 117 ARG B CD  1 
ATOM   6358  N  NE  . ARG C 2 171 ? 129.577 154.408 90.100  1.00 49.09  ? 117 ARG B NE  1 
ATOM   6359  C  CZ  . ARG C 2 171 ? 129.091 154.981 91.192  1.00 50.02  ? 117 ARG B CZ  1 
ATOM   6360  N  NH1 . ARG C 2 171 ? 129.480 156.186 91.570  1.00 49.55  ? 117 ARG B NH1 1 
ATOM   6361  N  NH2 . ARG C 2 171 ? 128.198 154.325 91.924  1.00 47.64  ? 117 ARG B NH2 1 
ATOM   6362  N  N   . LEU C 2 172 ? 132.581 152.267 85.487  1.00 40.74  ? 118 LEU B N   1 
ATOM   6363  C  CA  . LEU C 2 172 ? 133.535 152.652 84.461  1.00 40.32  ? 118 LEU B CA  1 
ATOM   6364  C  C   . LEU C 2 172 ? 133.398 154.135 84.154  1.00 45.67  ? 118 LEU B C   1 
ATOM   6365  O  O   . LEU C 2 172 ? 132.326 154.723 84.314  1.00 48.54  ? 118 LEU B O   1 
ATOM   6366  C  CB  . LEU C 2 172 ? 133.323 151.857 83.172  1.00 41.99  ? 118 LEU B CB  1 
ATOM   6367  C  CG  . LEU C 2 172 ? 133.174 150.343 83.266  1.00 44.29  ? 118 LEU B CG  1 
ATOM   6368  C  CD1 . LEU C 2 172 ? 132.997 149.753 81.882  1.00 43.80  ? 118 LEU B CD1 1 
ATOM   6369  C  CD2 . LEU C 2 172 ? 134.369 149.739 83.961  1.00 43.91  ? 118 LEU B CD2 1 
ATOM   6370  N  N   . HIS C 2 173 ? 134.491 154.728 83.695  1.00 47.89  ? 119 HIS B N   1 
ATOM   6371  C  CA  . HIS C 2 173 ? 134.555 156.126 83.313  1.00 45.97  ? 119 HIS B CA  1 
ATOM   6372  C  C   . HIS C 2 173 ? 135.151 156.229 81.918  1.00 50.69  ? 119 HIS B C   1 
ATOM   6373  O  O   . HIS C 2 173 ? 135.903 155.344 81.503  1.00 54.08  ? 119 HIS B O   1 
ATOM   6374  C  CB  . HIS C 2 173 ? 135.403 156.927 84.311  1.00 44.71  ? 119 HIS B CB  1 
ATOM   6375  C  CG  . HIS C 2 173 ? 135.013 156.720 85.742  1.00 47.08  ? 119 HIS B CG  1 
ATOM   6376  N  ND1 . HIS C 2 173 ? 135.271 155.552 86.424  1.00 44.83  ? 119 HIS B ND1 1 
ATOM   6377  C  CD2 . HIS C 2 173 ? 134.385 157.534 86.621  1.00 50.41  ? 119 HIS B CD2 1 
ATOM   6378  C  CE1 . HIS C 2 173 ? 134.825 155.656 87.661  1.00 41.37  ? 119 HIS B CE1 1 
ATOM   6379  N  NE2 . HIS C 2 173 ? 134.280 156.849 87.806  1.00 47.87  ? 119 HIS B NE2 1 
ATOM   6380  N  N   . PRO C 2 174 ? 134.825 157.286 81.168  1.00 54.32  ? 120 PRO B N   1 
ATOM   6381  C  CA  . PRO C 2 174 ? 135.263 157.349 79.761  1.00 54.89  ? 120 PRO B CA  1 
ATOM   6382  C  C   . PRO C 2 174 ? 136.764 157.259 79.588  1.00 58.11  ? 120 PRO B C   1 
ATOM   6383  O  O   . PRO C 2 174 ? 137.236 156.741 78.570  1.00 57.19  ? 120 PRO B O   1 
ATOM   6384  C  CB  . PRO C 2 174 ? 134.727 158.706 79.293  1.00 51.97  ? 120 PRO B CB  1 
ATOM   6385  C  CG  . PRO C 2 174 ? 133.581 158.974 80.177  1.00 53.52  ? 120 PRO B CG  1 
ATOM   6386  C  CD  . PRO C 2 174 ? 133.958 158.422 81.515  1.00 53.47  ? 120 PRO B CD  1 
ATOM   6387  N  N   . ASP C 2 175 ? 137.528 157.730 80.569  1.00 61.57  ? 121 ASP B N   1 
ATOM   6388  C  CA  . ASP C 2 175 ? 138.980 157.666 80.529  1.00 58.85  ? 121 ASP B CA  1 
ATOM   6389  C  C   . ASP C 2 175 ? 139.502 156.240 80.597  1.00 59.00  ? 121 ASP B C   1 
ATOM   6390  O  O   . ASP C 2 175 ? 140.694 156.021 80.366  1.00 63.97  ? 121 ASP B O   1 
ATOM   6391  C  CB  . ASP C 2 175 ? 139.546 158.488 81.687  1.00 57.73  ? 121 ASP B CB  1 
ATOM   6392  C  CG  . ASP C 2 175 ? 141.003 158.835 81.503  1.00 71.46  ? 121 ASP B CG  1 
ATOM   6393  O  OD1 . ASP C 2 175 ? 141.534 158.630 80.394  1.00 75.96  ? 121 ASP B OD1 1 
ATOM   6394  O  OD2 . ASP C 2 175 ? 141.620 159.320 82.473  1.00 71.85  ? 121 ASP B OD2 1 
ATOM   6395  N  N   . GLY C 2 176 ? 138.648 155.273 80.908  1.00 54.90  ? 122 GLY B N   1 
ATOM   6396  C  CA  . GLY C 2 176 ? 139.081 153.916 81.147  1.00 50.57  ? 122 GLY B CA  1 
ATOM   6397  C  C   . GLY C 2 176 ? 139.327 153.581 82.597  1.00 49.36  ? 122 GLY B C   1 
ATOM   6398  O  O   . GLY C 2 176 ? 139.941 152.549 82.880  1.00 49.91  ? 122 GLY B O   1 
ATOM   6399  N  N   . THR C 2 177 ? 138.878 154.421 83.520  1.00 46.77  ? 123 THR B N   1 
ATOM   6400  C  CA  . THR C 2 177 ? 139.112 154.218 84.941  1.00 44.04  ? 123 THR B CA  1 
ATOM   6401  C  C   . THR C 2 177 ? 138.036 153.319 85.530  1.00 41.17  ? 123 THR B C   1 
ATOM   6402  O  O   . THR C 2 177 ? 136.848 153.516 85.273  1.00 49.14  ? 123 THR B O   1 
ATOM   6403  C  CB  . THR C 2 177 ? 139.129 155.556 85.670  1.00 46.21  ? 123 THR B CB  1 
ATOM   6404  O  OG1 . THR C 2 177 ? 140.163 156.384 85.128  1.00 51.69  ? 123 THR B OG1 1 
ATOM   6405  C  CG2 . THR C 2 177 ? 139.388 155.340 87.129  1.00 39.94  ? 123 THR B CG2 1 
ATOM   6406  N  N   . VAL C 2 178 ? 138.457 152.348 86.333  1.00 35.81  ? 124 VAL B N   1 
ATOM   6407  C  CA  . VAL C 2 178 ? 137.569 151.374 86.947  1.00 35.20  ? 124 VAL B CA  1 
ATOM   6408  C  C   . VAL C 2 178 ? 137.544 151.604 88.449  1.00 36.73  ? 124 VAL B C   1 
ATOM   6409  O  O   . VAL C 2 178 ? 138.599 151.717 89.092  1.00 40.38  ? 124 VAL B O   1 
ATOM   6410  C  CB  . VAL C 2 178 ? 138.002 149.936 86.625  1.00 33.99  ? 124 VAL B CB  1 
ATOM   6411  C  CG1 . VAL C 2 178 ? 136.963 148.954 87.113  1.00 33.05  ? 124 VAL B CG1 1 
ATOM   6412  C  CG2 . VAL C 2 178 ? 138.232 149.781 85.136  1.00 36.41  ? 124 VAL B CG2 1 
ATOM   6413  N  N   . LEU C 2 179 ? 136.334 151.686 88.997  1.00 35.80  ? 125 LEU B N   1 
ATOM   6414  C  CA  . LEU C 2 179 ? 136.086 151.687 90.430  1.00 31.15  ? 125 LEU B CA  1 
ATOM   6415  C  C   . LEU C 2 179 ? 135.406 150.380 90.803  1.00 32.72  ? 125 LEU B C   1 
ATOM   6416  O  O   . LEU C 2 179 ? 134.366 150.032 90.232  1.00 37.73  ? 125 LEU B O   1 
ATOM   6417  C  CB  . LEU C 2 179 ? 135.210 152.871 90.834  1.00 33.34  ? 125 LEU B CB  1 
ATOM   6418  C  CG  . LEU C 2 179 ? 134.463 152.742 92.159  1.00 33.95  ? 125 LEU B CG  1 
ATOM   6419  C  CD1 . LEU C 2 179 ? 135.421 152.587 93.315  1.00 33.81  ? 125 LEU B CD1 1 
ATOM   6420  C  CD2 . LEU C 2 179 ? 133.571 153.934 92.377  1.00 35.35  ? 125 LEU B CD2 1 
ATOM   6421  N  N   . TYR C 2 180 ? 135.993 149.669 91.763  1.00 29.90  ? 126 TYR B N   1 
ATOM   6422  C  CA  . TYR C 2 180 ? 135.559 148.334 92.151  1.00 29.14  ? 126 TYR B CA  1 
ATOM   6423  C  C   . TYR C 2 180 ? 135.370 148.312 93.658  1.00 30.06  ? 126 TYR B C   1 
ATOM   6424  O  O   . TYR C 2 180 ? 136.330 148.513 94.401  1.00 33.57  ? 126 TYR B O   1 
ATOM   6425  C  CB  . TYR C 2 180 ? 136.599 147.306 91.706  1.00 28.15  ? 126 TYR B CB  1 
ATOM   6426  C  CG  . TYR C 2 180 ? 136.354 145.870 92.095  1.00 29.56  ? 126 TYR B CG  1 
ATOM   6427  C  CD1 . TYR C 2 180 ? 135.189 145.218 91.739  1.00 30.81  ? 126 TYR B CD1 1 
ATOM   6428  C  CD2 . TYR C 2 180 ? 137.317 145.154 92.781  1.00 28.19  ? 126 TYR B CD2 1 
ATOM   6429  C  CE1 . TYR C 2 180 ? 134.984 143.906 92.076  1.00 31.67  ? 126 TYR B CE1 1 
ATOM   6430  C  CE2 . TYR C 2 180 ? 137.120 143.849 93.117  1.00 30.41  ? 126 TYR B CE2 1 
ATOM   6431  C  CZ  . TYR C 2 180 ? 135.952 143.228 92.769  1.00 31.81  ? 126 TYR B CZ  1 
ATOM   6432  O  OH  . TYR C 2 180 ? 135.756 141.914 93.109  1.00 34.92  ? 126 TYR B OH  1 
ATOM   6433  N  N   . GLY C 2 181 ? 134.152 148.070 94.108  1.00 27.30  ? 127 GLY B N   1 
ATOM   6434  C  CA  . GLY C 2 181 ? 133.823 148.150 95.526  1.00 26.25  ? 127 GLY B CA  1 
ATOM   6435  C  C   . GLY C 2 181 ? 133.261 146.852 96.067  1.00 27.27  ? 127 GLY B C   1 
ATOM   6436  O  O   . GLY C 2 181 ? 132.443 146.209 95.414  1.00 34.08  ? 127 GLY B O   1 
ATOM   6437  N  N   . LEU C 2 182 ? 133.684 146.491 97.281  1.00 23.90  ? 128 LEU B N   1 
ATOM   6438  C  CA  . LEU C 2 182 ? 133.247 145.269 97.944  1.00 23.05  ? 128 LEU B CA  1 
ATOM   6439  C  C   . LEU C 2 182 ? 132.833 145.566 99.378  1.00 22.86  ? 128 LEU B C   1 
ATOM   6440  O  O   . LEU C 2 182 ? 133.385 146.455 100.018 1.00 25.06  ? 128 LEU B O   1 
ATOM   6441  C  CB  . LEU C 2 182 ? 134.356 144.222 97.960  1.00 22.79  ? 128 LEU B CB  1 
ATOM   6442  C  CG  . LEU C 2 182 ? 134.938 143.764 96.631  1.00 23.81  ? 128 LEU B CG  1 
ATOM   6443  C  CD1 . LEU C 2 182 ? 136.217 143.017 96.871  1.00 22.68  ? 128 LEU B CD1 1 
ATOM   6444  C  CD2 . LEU C 2 182 ? 133.949 142.880 95.926  1.00 27.98  ? 128 LEU B CD2 1 
ATOM   6445  N  N   . ARG C 2 183 ? 131.871 144.807 99.893  1.00 21.80  ? 129 ARG B N   1 
ATOM   6446  C  CA  . ARG C 2 183 ? 131.495 144.874 101.303 1.00 22.98  ? 129 ARG B CA  1 
ATOM   6447  C  C   . ARG C 2 183 ? 131.961 143.591 101.974 1.00 23.41  ? 129 ARG B C   1 
ATOM   6448  O  O   . ARG C 2 183 ? 131.451 142.510 101.674 1.00 27.34  ? 129 ARG B O   1 
ATOM   6449  C  CB  . ARG C 2 183 ? 129.994 145.071 101.482 1.00 22.33  ? 129 ARG B CB  1 
ATOM   6450  C  CG  . ARG C 2 183 ? 129.582 145.109 102.936 1.00 23.14  ? 129 ARG B CG  1 
ATOM   6451  C  CD  . ARG C 2 183 ? 128.314 145.895 103.148 1.00 26.61  ? 129 ARG B CD  1 
ATOM   6452  N  NE  . ARG C 2 183 ? 127.138 145.040 103.118 1.00 31.17  ? 129 ARG B NE  1 
ATOM   6453  C  CZ  . ARG C 2 183 ? 126.467 144.654 104.192 1.00 28.91  ? 129 ARG B CZ  1 
ATOM   6454  N  NH1 . ARG C 2 183 ? 126.797 145.071 105.400 1.00 27.14  ? 129 ARG B NH1 1 
ATOM   6455  N  NH2 . ARG C 2 183 ? 125.434 143.831 104.048 1.00 26.29  ? 129 ARG B NH2 1 
ATOM   6456  N  N   . ILE C 2 184 ? 132.913 143.717 102.898 1.00 22.82  ? 130 ILE B N   1 
ATOM   6457  C  CA  . ILE C 2 184 ? 133.693 142.592 103.397 1.00 22.96  ? 130 ILE B CA  1 
ATOM   6458  C  C   . ILE C 2 184 ? 133.650 142.568 104.915 1.00 26.08  ? 130 ILE B C   1 
ATOM   6459  O  O   . ILE C 2 184 ? 133.801 143.607 105.563 1.00 32.50  ? 130 ILE B O   1 
ATOM   6460  C  CB  . ILE C 2 184 ? 135.154 142.675 102.911 1.00 23.24  ? 130 ILE B CB  1 
ATOM   6461  C  CG1 . ILE C 2 184 ? 135.214 142.591 101.393 1.00 24.99  ? 130 ILE B CG1 1 
ATOM   6462  C  CG2 . ILE C 2 184 ? 136.008 141.599 103.549 1.00 23.70  ? 130 ILE B CG2 1 
ATOM   6463  C  CD1 . ILE C 2 184 ? 136.537 143.004 100.832 1.00 25.74  ? 130 ILE B CD1 1 
ATOM   6464  N  N   . THR C 2 185 ? 133.446 141.382 105.480 1.00 26.00  ? 131 THR B N   1 
ATOM   6465  C  CA  . THR C 2 185 ? 133.637 141.130 106.901 1.00 26.39  ? 131 THR B CA  1 
ATOM   6466  C  C   . THR C 2 185 ? 134.837 140.211 107.078 1.00 28.11  ? 131 THR B C   1 
ATOM   6467  O  O   . THR C 2 185 ? 134.885 139.131 106.486 1.00 30.22  ? 131 THR B O   1 
ATOM   6468  C  CB  . THR C 2 185 ? 132.399 140.492 107.528 1.00 26.57  ? 131 THR B CB  1 
ATOM   6469  O  OG1 . THR C 2 185 ? 131.308 141.415 107.484 1.00 34.02  ? 131 THR B OG1 1 
ATOM   6470  C  CG2 . THR C 2 185 ? 132.668 140.112 108.966 1.00 25.58  ? 131 THR B CG2 1 
ATOM   6471  N  N   . THR C 2 186 ? 135.801 140.639 107.885 1.00 28.87  ? 132 THR B N   1 
ATOM   6472  C  CA  . THR C 2 186 ? 137.037 139.899 108.078 1.00 30.71  ? 132 THR B CA  1 
ATOM   6473  C  C   . THR C 2 186 ? 137.349 139.771 109.561 1.00 32.77  ? 132 THR B C   1 
ATOM   6474  O  O   . THR C 2 186 ? 137.225 140.733 110.318 1.00 33.62  ? 132 THR B O   1 
ATOM   6475  C  CB  . THR C 2 186 ? 138.209 140.574 107.342 1.00 31.99  ? 132 THR B CB  1 
ATOM   6476  O  OG1 . THR C 2 186 ? 139.434 139.920 107.678 1.00 35.32  ? 132 THR B OG1 1 
ATOM   6477  C  CG2 . THR C 2 186 ? 138.309 142.031 107.709 1.00 30.82  ? 132 THR B CG2 1 
ATOM   6478  N  N   . THR C 2 187 ? 137.745 138.576 109.973 1.00 31.96  ? 133 THR B N   1 
ATOM   6479  C  CA  . THR C 2 187 ? 138.217 138.328 111.331 1.00 31.37  ? 133 THR B CA  1 
ATOM   6480  C  C   . THR C 2 187 ? 139.738 138.367 111.287 1.00 31.21  ? 133 THR B C   1 
ATOM   6481  O  O   . THR C 2 187 ? 140.383 137.395 110.899 1.00 34.85  ? 133 THR B O   1 
ATOM   6482  C  CB  . THR C 2 187 ? 137.698 136.996 111.855 1.00 32.75  ? 133 THR B CB  1 
ATOM   6483  O  OG1 . THR C 2 187 ? 136.271 137.035 111.924 1.00 39.21  ? 133 THR B OG1 1 
ATOM   6484  C  CG2 . THR C 2 187 ? 138.240 136.723 113.230 1.00 30.58  ? 133 THR B CG2 1 
ATOM   6485  N  N   . ALA C 2 188 ? 140.309 139.498 111.671 1.00 31.20  ? 134 ALA B N   1 
ATOM   6486  C  CA  . ALA C 2 188 ? 141.736 139.737 111.543 1.00 30.09  ? 134 ALA B CA  1 
ATOM   6487  C  C   . ALA C 2 188 ? 142.443 139.482 112.865 1.00 34.87  ? 134 ALA B C   1 
ATOM   6488  O  O   . ALA C 2 188 ? 141.955 139.871 113.928 1.00 38.75  ? 134 ALA B O   1 
ATOM   6489  C  CB  . ALA C 2 188 ? 142.001 141.165 111.071 1.00 30.12  ? 134 ALA B CB  1 
ATOM   6490  N  N   . ALA C 2 189 ? 143.598 138.828 112.787 1.00 35.15  ? 135 ALA B N   1 
ATOM   6491  C  CA  . ALA C 2 189 ? 144.365 138.473 113.970 1.00 35.57  ? 135 ALA B CA  1 
ATOM   6492  C  C   . ALA C 2 189 ? 145.071 139.693 114.541 1.00 40.51  ? 135 ALA B C   1 
ATOM   6493  O  O   . ALA C 2 189 ? 145.738 140.434 113.817 1.00 42.09  ? 135 ALA B O   1 
ATOM   6494  C  CB  . ALA C 2 189 ? 145.386 137.391 113.633 1.00 31.15  ? 135 ALA B CB  1 
ATOM   6495  N  N   . CYS C 2 190 ? 144.925 139.891 115.845 1.00 44.32  ? 136 CYS B N   1 
ATOM   6496  C  CA  . CYS C 2 190 ? 145.560 140.997 116.553 1.00 44.36  ? 136 CYS B CA  1 
ATOM   6497  C  C   . CYS C 2 190 ? 146.190 140.396 117.802 1.00 49.72  ? 136 CYS B C   1 
ATOM   6498  O  O   . CYS C 2 190 ? 145.491 140.120 118.777 1.00 58.10  ? 136 CYS B O   1 
ATOM   6499  C  CB  . CYS C 2 190 ? 144.553 142.087 116.898 1.00 46.70  ? 136 CYS B CB  1 
ATOM   6500  S  SG  . CYS C 2 190 ? 145.210 143.483 117.826 1.00 65.46  ? 136 CYS B SG  1 
ATOM   6501  N  N   . MET C 2 191 ? 147.498 140.171 117.764 1.00 49.97  ? 137 MET B N   1 
ATOM   6502  C  CA  . MET C 2 191 ? 148.176 139.613 118.923 1.00 53.75  ? 137 MET B CA  1 
ATOM   6503  C  C   . MET C 2 191 ? 148.283 140.671 120.009 1.00 54.03  ? 137 MET B C   1 
ATOM   6504  O  O   . MET C 2 191 ? 148.871 141.735 119.800 1.00 57.75  ? 137 MET B O   1 
ATOM   6505  C  CB  . MET C 2 191 ? 149.558 139.098 118.536 1.00 57.57  ? 137 MET B CB  1 
ATOM   6506  C  CG  . MET C 2 191 ? 150.044 137.968 119.411 1.00 63.16  ? 137 MET B CG  1 
ATOM   6507  S  SD  . MET C 2 191 ? 148.904 136.577 119.399 1.00 80.84  ? 137 MET B SD  1 
ATOM   6508  C  CE  . MET C 2 191 ? 149.660 135.524 120.624 1.00 70.93  ? 137 MET B CE  1 
ATOM   6509  N  N   . MET C 2 192 ? 147.713 140.379 121.170 1.00 49.43  ? 138 MET B N   1 
ATOM   6510  C  CA  . MET C 2 192 ? 147.559 141.352 122.238 1.00 50.76  ? 138 MET B CA  1 
ATOM   6511  C  C   . MET C 2 192 ? 148.522 141.051 123.374 1.00 53.28  ? 138 MET B C   1 
ATOM   6512  O  O   . MET C 2 192 ? 148.800 139.888 123.674 1.00 54.46  ? 138 MET B O   1 
ATOM   6513  C  CB  . MET C 2 192 ? 146.129 141.352 122.770 1.00 48.91  ? 138 MET B CB  1 
ATOM   6514  C  CG  . MET C 2 192 ? 145.084 141.388 121.697 1.00 52.60  ? 138 MET B CG  1 
ATOM   6515  S  SD  . MET C 2 192 ? 143.430 141.561 122.361 1.00 69.93  ? 138 MET B SD  1 
ATOM   6516  C  CE  . MET C 2 192 ? 142.505 141.548 120.836 1.00 52.85  ? 138 MET B CE  1 
ATOM   6517  N  N   . ASP C 2 193 ? 149.018 142.106 124.007 1.00 52.78  ? 139 ASP B N   1 
ATOM   6518  C  CA  . ASP C 2 193 ? 149.885 141.990 125.174 1.00 54.79  ? 139 ASP B CA  1 
ATOM   6519  C  C   . ASP C 2 193 ? 149.053 142.359 126.394 1.00 52.79  ? 139 ASP B C   1 
ATOM   6520  O  O   . ASP C 2 193 ? 148.792 143.537 126.646 1.00 54.22  ? 139 ASP B O   1 
ATOM   6521  C  CB  . ASP C 2 193 ? 151.107 142.888 125.034 1.00 59.89  ? 139 ASP B CB  1 
ATOM   6522  C  CG  . ASP C 2 193 ? 152.149 142.613 126.088 1.00 64.78  ? 139 ASP B CG  1 
ATOM   6523  O  OD1 . ASP C 2 193 ? 152.045 141.574 126.766 1.00 66.03  ? 139 ASP B OD1 1 
ATOM   6524  O  OD2 . ASP C 2 193 ? 153.072 143.437 126.242 1.00 67.00  ? 139 ASP B OD2 1 
ATOM   6525  N  N   . LEU C 2 194 ? 148.632 141.350 127.154 1.00 48.56  ? 140 LEU B N   1 
ATOM   6526  C  CA  . LEU C 2 194 ? 147.783 141.556 128.318 1.00 47.63  ? 140 LEU B CA  1 
ATOM   6527  C  C   . LEU C 2 194 ? 148.558 141.481 129.623 1.00 52.80  ? 140 LEU B C   1 
ATOM   6528  O  O   . LEU C 2 194 ? 147.995 141.110 130.655 1.00 54.28  ? 140 LEU B O   1 
ATOM   6529  C  CB  . LEU C 2 194 ? 146.634 140.553 128.327 1.00 46.07  ? 140 LEU B CB  1 
ATOM   6530  C  CG  . LEU C 2 194 ? 145.540 140.835 127.303 1.00 48.56  ? 140 LEU B CG  1 
ATOM   6531  C  CD1 . LEU C 2 194 ? 145.701 139.932 126.113 1.00 54.35  ? 140 LEU B CD1 1 
ATOM   6532  C  CD2 . LEU C 2 194 ? 144.180 140.668 127.920 1.00 50.98  ? 140 LEU B CD2 1 
ATOM   6533  N  N   . ARG C 2 195 ? 149.838 141.844 129.603 1.00 52.96  ? 141 ARG B N   1 
ATOM   6534  C  CA  . ARG C 2 195 ? 150.631 141.861 130.821 1.00 49.59  ? 141 ARG B CA  1 
ATOM   6535  C  C   . ARG C 2 195 ? 150.274 143.018 131.740 1.00 52.38  ? 141 ARG B C   1 
ATOM   6536  O  O   . ARG C 2 195 ? 150.766 143.057 132.869 1.00 60.89  ? 141 ARG B O   1 
ATOM   6537  C  CB  . ARG C 2 195 ? 152.117 141.909 130.475 1.00 48.80  ? 141 ARG B CB  1 
ATOM   6538  C  CG  . ARG C 2 195 ? 152.685 140.568 130.069 1.00 54.28  ? 141 ARG B CG  1 
ATOM   6539  C  CD  . ARG C 2 195 ? 154.019 140.702 129.356 1.00 59.72  ? 141 ARG B CD  1 
ATOM   6540  N  NE  . ARG C 2 195 ? 154.603 139.396 129.072 1.00 72.69  ? 141 ARG B NE  1 
ATOM   6541  C  CZ  . ARG C 2 195 ? 154.390 138.696 127.966 1.00 74.49  ? 141 ARG B CZ  1 
ATOM   6542  N  NH1 . ARG C 2 195 ? 153.626 139.158 126.990 1.00 69.86  ? 141 ARG B NH1 1 
ATOM   6543  N  NH2 . ARG C 2 195 ? 154.960 137.502 127.833 1.00 71.42  ? 141 ARG B NH2 1 
ATOM   6544  N  N   . ARG C 2 196 ? 149.446 143.960 131.287 1.00 52.18  ? 142 ARG B N   1 
ATOM   6545  C  CA  . ARG C 2 196 ? 148.982 145.071 132.108 1.00 51.38  ? 142 ARG B CA  1 
ATOM   6546  C  C   . ARG C 2 196 ? 147.474 145.041 132.309 1.00 50.97  ? 142 ARG B C   1 
ATOM   6547  O  O   . ARG C 2 196 ? 146.880 146.059 132.669 1.00 52.86  ? 142 ARG B O   1 
ATOM   6548  C  CB  . ARG C 2 196 ? 149.395 146.403 131.487 1.00 53.39  ? 142 ARG B CB  1 
ATOM   6549  C  CG  . ARG C 2 196 ? 150.876 146.653 131.468 1.00 55.59  ? 142 ARG B CG  1 
ATOM   6550  C  CD  . ARG C 2 196 ? 151.186 147.879 130.644 1.00 60.16  ? 142 ARG B CD  1 
ATOM   6551  N  NE  . ARG C 2 196 ? 152.517 148.401 130.918 1.00 70.02  ? 142 ARG B NE  1 
ATOM   6552  C  CZ  . ARG C 2 196 ? 152.758 149.460 131.676 1.00 73.50  ? 142 ARG B CZ  1 
ATOM   6553  N  NH1 . ARG C 2 196 ? 151.778 150.136 132.248 1.00 71.63  ? 142 ARG B NH1 1 
ATOM   6554  N  NH2 . ARG C 2 196 ? 154.015 149.849 131.864 1.00 73.67  ? 142 ARG B NH2 1 
ATOM   6555  N  N   . TYR C 2 197 ? 146.846 143.901 132.065 1.00 47.10  ? 143 TYR B N   1 
ATOM   6556  C  CA  . TYR C 2 197 ? 145.404 143.795 132.202 1.00 50.14  ? 143 TYR B CA  1 
ATOM   6557  C  C   . TYR C 2 197 ? 145.002 144.042 133.654 1.00 53.78  ? 143 TYR B C   1 
ATOM   6558  O  O   . TYR C 2 197 ? 145.687 143.582 134.572 1.00 59.41  ? 143 TYR B O   1 
ATOM   6559  C  CB  . TYR C 2 197 ? 144.955 142.408 131.743 1.00 51.08  ? 143 TYR B CB  1 
ATOM   6560  C  CG  . TYR C 2 197 ? 143.470 142.151 131.766 1.00 51.49  ? 143 TYR B CG  1 
ATOM   6561  C  CD1 . TYR C 2 197 ? 142.685 142.421 130.662 1.00 52.76  ? 143 TYR B CD1 1 
ATOM   6562  C  CD2 . TYR C 2 197 ? 142.861 141.604 132.881 1.00 50.96  ? 143 TYR B CD2 1 
ATOM   6563  C  CE1 . TYR C 2 197 ? 141.331 142.171 130.674 1.00 55.19  ? 143 TYR B CE1 1 
ATOM   6564  C  CE2 . TYR C 2 197 ? 141.511 141.354 132.903 1.00 56.84  ? 143 TYR B CE2 1 
ATOM   6565  C  CZ  . TYR C 2 197 ? 140.750 141.638 131.796 1.00 58.80  ? 143 TYR B CZ  1 
ATOM   6566  O  OH  . TYR C 2 197 ? 139.399 141.389 131.812 1.00 65.44  ? 143 TYR B OH  1 
ATOM   6567  N  N   . PRO C 2 198 ? 143.896 144.750 133.905 1.00 53.95  ? 144 PRO B N   1 
ATOM   6568  C  CA  . PRO C 2 198 ? 142.922 145.300 132.961 1.00 51.98  ? 144 PRO B CA  1 
ATOM   6569  C  C   . PRO C 2 198 ? 143.137 146.763 132.604 1.00 52.88  ? 144 PRO B C   1 
ATOM   6570  O  O   . PRO C 2 198 ? 142.168 147.483 132.412 1.00 56.10  ? 144 PRO B O   1 
ATOM   6571  C  CB  . PRO C 2 198 ? 141.608 145.110 133.717 1.00 55.24  ? 144 PRO B CB  1 
ATOM   6572  C  CG  . PRO C 2 198 ? 141.993 145.386 135.138 1.00 56.59  ? 144 PRO B CG  1 
ATOM   6573  C  CD  . PRO C 2 198 ? 143.424 144.903 135.290 1.00 57.48  ? 144 PRO B CD  1 
ATOM   6574  N  N   . LEU C 2 199 ? 144.373 147.244 132.513 1.00 51.80  ? 145 LEU B N   1 
ATOM   6575  C  CA  . LEU C 2 199 ? 144.665 148.610 132.096 1.00 50.60  ? 145 LEU B CA  1 
ATOM   6576  C  C   . LEU C 2 199 ? 145.607 148.618 130.899 1.00 52.83  ? 145 LEU B C   1 
ATOM   6577  O  O   . LEU C 2 199 ? 146.503 149.456 130.793 1.00 54.13  ? 145 LEU B O   1 
ATOM   6578  C  CB  . LEU C 2 199 ? 145.259 149.420 133.244 1.00 52.24  ? 145 LEU B CB  1 
ATOM   6579  C  CG  . LEU C 2 199 ? 144.339 149.951 134.347 1.00 54.49  ? 145 LEU B CG  1 
ATOM   6580  C  CD1 . LEU C 2 199 ? 143.842 148.842 135.252 1.00 55.20  ? 145 LEU B CD1 1 
ATOM   6581  C  CD2 . LEU C 2 199 ? 145.070 151.002 135.155 1.00 58.52  ? 145 LEU B CD2 1 
ATOM   6582  N  N   . ASP C 2 200 ? 145.407 147.679 129.983 1.00 54.15  ? 146 ASP B N   1 
ATOM   6583  C  CA  . ASP C 2 200 ? 146.293 147.485 128.849 1.00 48.61  ? 146 ASP B CA  1 
ATOM   6584  C  C   . ASP C 2 200 ? 145.866 148.347 127.666 1.00 51.93  ? 146 ASP B C   1 
ATOM   6585  O  O   . ASP C 2 200 ? 144.724 148.798 127.572 1.00 56.56  ? 146 ASP B O   1 
ATOM   6586  C  CB  . ASP C 2 200 ? 146.311 146.015 128.444 1.00 47.73  ? 146 ASP B CB  1 
ATOM   6587  C  CG  . ASP C 2 200 ? 144.921 145.463 128.200 1.00 50.52  ? 146 ASP B CG  1 
ATOM   6588  O  OD1 . ASP C 2 200 ? 143.998 145.816 128.954 1.00 49.75  ? 146 ASP B OD1 1 
ATOM   6589  O  OD2 . ASP C 2 200 ? 144.745 144.681 127.248 1.00 54.21  ? 146 ASP B OD2 1 
ATOM   6590  N  N   . GLU C 2 201 ? 146.812 148.570 126.757 1.00 52.90  ? 147 GLU B N   1 
ATOM   6591  C  CA  . GLU C 2 201 ? 146.595 149.341 125.541 1.00 48.92  ? 147 GLU B CA  1 
ATOM   6592  C  C   . GLU C 2 201 ? 147.021 148.495 124.352 1.00 49.40  ? 147 GLU B C   1 
ATOM   6593  O  O   . GLU C 2 201 ? 148.118 147.929 124.355 1.00 52.64  ? 147 GLU B O   1 
ATOM   6594  C  CB  . GLU C 2 201 ? 147.387 150.648 125.580 1.00 49.31  ? 147 GLU B CB  1 
ATOM   6595  C  CG  . GLU C 2 201 ? 147.089 151.598 124.447 1.00 56.08  ? 147 GLU B CG  1 
ATOM   6596  C  CD  . GLU C 2 201 ? 147.962 152.834 124.487 1.00 68.96  ? 147 GLU B CD  1 
ATOM   6597  O  OE1 . GLU C 2 201 ? 149.085 152.752 125.030 1.00 69.68  ? 147 GLU B OE1 1 
ATOM   6598  O  OE2 . GLU C 2 201 ? 147.527 153.890 123.982 1.00 73.62  ? 147 GLU B OE2 1 
ATOM   6599  N  N   . GLN C 2 202 ? 146.167 148.412 123.338 1.00 46.28  ? 148 GLN B N   1 
ATOM   6600  C  CA  . GLN C 2 202 ? 146.381 147.501 122.225 1.00 42.65  ? 148 GLN B CA  1 
ATOM   6601  C  C   . GLN C 2 202 ? 146.569 148.263 120.922 1.00 42.99  ? 148 GLN B C   1 
ATOM   6602  O  O   . GLN C 2 202 ? 146.249 149.445 120.817 1.00 46.43  ? 148 GLN B O   1 
ATOM   6603  C  CB  . GLN C 2 202 ? 145.218 146.518 122.081 1.00 41.69  ? 148 GLN B CB  1 
ATOM   6604  C  CG  . GLN C 2 202 ? 144.850 145.814 123.364 1.00 41.59  ? 148 GLN B CG  1 
ATOM   6605  C  CD  . GLN C 2 202 ? 146.005 145.063 123.977 1.00 44.27  ? 148 GLN B CD  1 
ATOM   6606  O  OE1 . GLN C 2 202 ? 146.946 144.677 123.292 1.00 50.10  ? 148 GLN B OE1 1 
ATOM   6607  N  NE2 . GLN C 2 202 ? 145.940 144.848 125.281 1.00 47.71  ? 148 GLN B NE2 1 
ATOM   6608  N  N   . ASN C 2 203 ? 147.099 147.560 119.924 1.00 39.32  ? 149 ASN B N   1 
ATOM   6609  C  CA  . ASN C 2 203 ? 147.327 148.121 118.592 1.00 36.95  ? 149 ASN B CA  1 
ATOM   6610  C  C   . ASN C 2 203 ? 146.959 147.033 117.592 1.00 42.24  ? 149 ASN B C   1 
ATOM   6611  O  O   . ASN C 2 203 ? 147.708 146.071 117.411 1.00 51.76  ? 149 ASN B O   1 
ATOM   6612  C  CB  . ASN C 2 203 ? 148.771 148.585 118.431 1.00 37.46  ? 149 ASN B CB  1 
ATOM   6613  C  CG  . ASN C 2 203 ? 149.102 149.022 117.017 1.00 43.22  ? 149 ASN B CG  1 
ATOM   6614  O  OD1 . ASN C 2 203 ? 148.240 149.090 116.153 1.00 43.42  ? 149 ASN B OD1 1 
ATOM   6615  N  ND2 . ASN C 2 203 ? 150.371 149.332 116.784 1.00 50.10  ? 149 ASN B ND2 1 
ATOM   6616  N  N   . CYS C 2 204 ? 145.810 147.188 116.942 1.00 37.86  ? 150 CYS B N   1 
ATOM   6617  C  CA  . CYS C 2 204 ? 145.299 146.187 116.016 1.00 37.13  ? 150 CYS B CA  1 
ATOM   6618  C  C   . CYS C 2 204 ? 145.386 146.705 114.589 1.00 37.96  ? 150 CYS B C   1 
ATOM   6619  O  O   . CYS C 2 204 ? 144.965 147.828 114.307 1.00 42.79  ? 150 CYS B O   1 
ATOM   6620  C  CB  . CYS C 2 204 ? 143.861 145.803 116.359 1.00 40.07  ? 150 CYS B CB  1 
ATOM   6621  S  SG  . CYS C 2 204 ? 143.694 144.843 117.886 1.00 71.91  ? 150 CYS B SG  1 
ATOM   6622  N  N   . THR C 2 205 ? 145.929 145.887 113.693 1.00 38.52  ? 151 THR B N   1 
ATOM   6623  C  CA  . THR C 2 205 ? 146.231 146.312 112.336 1.00 36.20  ? 151 THR B CA  1 
ATOM   6624  C  C   . THR C 2 205 ? 145.486 145.469 111.312 1.00 35.32  ? 151 THR B C   1 
ATOM   6625  O  O   . THR C 2 205 ? 145.073 144.339 111.577 1.00 37.37  ? 151 THR B O   1 
ATOM   6626  C  CB  . THR C 2 205 ? 147.730 146.226 112.038 1.00 36.10  ? 151 THR B CB  1 
ATOM   6627  O  OG1 . THR C 2 205 ? 148.142 144.855 112.063 1.00 38.74  ? 151 THR B OG1 1 
ATOM   6628  C  CG2 . THR C 2 205 ? 148.529 147.001 113.060 1.00 39.62  ? 151 THR B CG2 1 
ATOM   6629  N  N   . LEU C 2 206 ? 145.316 146.056 110.131 1.00 34.70  ? 152 LEU B N   1 
ATOM   6630  C  CA  . LEU C 2 206 ? 144.921 145.350 108.925 1.00 33.94  ? 152 LEU B CA  1 
ATOM   6631  C  C   . LEU C 2 206 ? 145.983 145.608 107.872 1.00 35.24  ? 152 LEU B C   1 
ATOM   6632  O  O   . LEU C 2 206 ? 146.303 146.766 107.581 1.00 37.60  ? 152 LEU B O   1 
ATOM   6633  C  CB  . LEU C 2 206 ? 143.555 145.814 108.423 1.00 31.31  ? 152 LEU B CB  1 
ATOM   6634  C  CG  . LEU C 2 206 ? 142.969 145.017 107.261 1.00 30.42  ? 152 LEU B CG  1 
ATOM   6635  C  CD1 . LEU C 2 206 ? 142.545 143.643 107.734 1.00 31.11  ? 152 LEU B CD1 1 
ATOM   6636  C  CD2 . LEU C 2 206 ? 141.814 145.755 106.629 1.00 28.11  ? 152 LEU B CD2 1 
ATOM   6637  N  N   . GLU C 2 207 ? 146.533 144.537 107.311 1.00 32.39  ? 153 GLU B N   1 
ATOM   6638  C  CA  . GLU C 2 207 ? 147.581 144.618 106.305 1.00 32.19  ? 153 GLU B CA  1 
ATOM   6639  C  C   . GLU C 2 207 ? 147.009 144.240 104.949 1.00 33.87  ? 153 GLU B C   1 
ATOM   6640  O  O   . GLU C 2 207 ? 146.401 143.178 104.803 1.00 37.78  ? 153 GLU B O   1 
ATOM   6641  C  CB  . GLU C 2 207 ? 148.747 143.697 106.656 1.00 32.64  ? 153 GLU B CB  1 
ATOM   6642  C  CG  . GLU C 2 207 ? 149.236 143.821 108.086 1.00 38.59  ? 153 GLU B CG  1 
ATOM   6643  C  CD  . GLU C 2 207 ? 150.100 145.042 108.320 1.00 47.88  ? 153 GLU B CD  1 
ATOM   6644  O  OE1 . GLU C 2 207 ? 150.521 145.680 107.338 1.00 48.64  ? 153 GLU B OE1 1 
ATOM   6645  O  OE2 . GLU C 2 207 ? 150.367 145.366 109.492 1.00 49.89  ? 153 GLU B OE2 1 
ATOM   6646  N  N   . ILE C 2 208 ? 147.218 145.102 103.962 1.00 31.62  ? 154 ILE B N   1 
ATOM   6647  C  CA  . ILE C 2 208 ? 146.662 144.967 102.625 1.00 29.86  ? 154 ILE B CA  1 
ATOM   6648  C  C   . ILE C 2 208 ? 147.828 144.815 101.664 1.00 32.31  ? 154 ILE B C   1 
ATOM   6649  O  O   . ILE C 2 208 ? 148.731 145.656 101.651 1.00 38.03  ? 154 ILE B O   1 
ATOM   6650  C  CB  . ILE C 2 208 ? 145.807 146.193 102.264 1.00 29.52  ? 154 ILE B CB  1 
ATOM   6651  C  CG1 . ILE C 2 208 ? 144.705 146.386 103.298 1.00 28.08  ? 154 ILE B CG1 1 
ATOM   6652  C  CG2 . ILE C 2 208 ? 145.228 146.068 100.884 1.00 30.93  ? 154 ILE B CG2 1 
ATOM   6653  C  CD1 . ILE C 2 208 ? 143.968 147.679 103.153 1.00 32.00  ? 154 ILE B CD1 1 
ATOM   6654  N  N   . GLU C 2 209 ? 147.825 143.748 100.871 1.00 29.20  ? 155 GLU B N   1 
ATOM   6655  C  CA  . GLU C 2 209 ? 149.001 143.470 100.066 1.00 31.25  ? 155 GLU B CA  1 
ATOM   6656  C  C   . GLU C 2 209 ? 148.618 142.806 98.753  1.00 34.03  ? 155 GLU B C   1 
ATOM   6657  O  O   . GLU C 2 209 ? 147.599 142.123 98.655  1.00 36.64  ? 155 GLU B O   1 
ATOM   6658  C  CB  . GLU C 2 209 ? 149.988 142.586 100.831 1.00 33.14  ? 155 GLU B CB  1 
ATOM   6659  C  CG  . GLU C 2 209 ? 151.344 142.470 100.176 1.00 37.09  ? 155 GLU B CG  1 
ATOM   6660  C  CD  . GLU C 2 209 ? 152.321 141.660 100.984 1.00 45.46  ? 155 GLU B CD  1 
ATOM   6661  O  OE1 . GLU C 2 209 ? 152.015 141.349 102.152 1.00 48.74  ? 155 GLU B OE1 1 
ATOM   6662  O  OE2 . GLU C 2 209 ? 153.399 141.334 100.452 1.00 48.07  ? 155 GLU B OE2 1 
ATOM   6663  N  N   . SER C 2 210 ? 149.451 143.026 97.743  1.00 34.12  ? 156 SER B N   1 
ATOM   6664  C  CA  . SER C 2 210 ? 149.349 142.302 96.489  1.00 34.61  ? 156 SER B CA  1 
ATOM   6665  C  C   . SER C 2 210 ? 149.991 140.932 96.632  1.00 36.80  ? 156 SER B C   1 
ATOM   6666  O  O   . SER C 2 210 ? 151.050 140.795 97.243  1.00 42.03  ? 156 SER B O   1 
ATOM   6667  C  CB  . SER C 2 210 ? 150.033 143.090 95.377  1.00 36.89  ? 156 SER B CB  1 
ATOM   6668  O  OG  . SER C 2 210 ? 149.974 142.405 94.147  1.00 38.83  ? 156 SER B OG  1 
ATOM   6669  N  N   . TYR C 2 211 ? 149.351 139.909 96.067  1.00 34.16  ? 157 TYR B N   1 
ATOM   6670  C  CA  . TYR C 2 211 ? 149.861 138.549 96.204  1.00 34.66  ? 157 TYR B CA  1 
ATOM   6671  C  C   . TYR C 2 211 ? 150.771 138.146 95.049  1.00 36.54  ? 157 TYR B C   1 
ATOM   6672  O  O   . TYR C 2 211 ? 151.903 137.713 95.275  1.00 39.22  ? 157 TYR B O   1 
ATOM   6673  C  CB  . TYR C 2 211 ? 148.721 137.531 96.342  1.00 29.95  ? 157 TYR B CB  1 
ATOM   6674  C  CG  . TYR C 2 211 ? 149.256 136.198 96.789  1.00 33.12  ? 157 TYR B CG  1 
ATOM   6675  C  CD1 . TYR C 2 211 ? 149.390 135.902 98.133  1.00 31.67  ? 157 TYR B CD1 1 
ATOM   6676  C  CD2 . TYR C 2 211 ? 149.689 135.259 95.869  1.00 37.05  ? 157 TYR B CD2 1 
ATOM   6677  C  CE1 . TYR C 2 211 ? 149.913 134.708 98.546  1.00 31.19  ? 157 TYR B CE1 1 
ATOM   6678  C  CE2 . TYR C 2 211 ? 150.207 134.060 96.276  1.00 36.62  ? 157 TYR B CE2 1 
ATOM   6679  C  CZ  . TYR C 2 211 ? 150.318 133.793 97.611  1.00 35.76  ? 157 TYR B CZ  1 
ATOM   6680  O  OH  . TYR C 2 211 ? 150.841 132.595 98.007  1.00 44.86  ? 157 TYR B OH  1 
ATOM   6681  N  N   . GLY C 2 212 ? 150.295 138.252 93.816  1.00 36.53  ? 158 GLY B N   1 
ATOM   6682  C  CA  . GLY C 2 212 ? 151.067 137.735 92.707  1.00 36.90  ? 158 GLY B CA  1 
ATOM   6683  C  C   . GLY C 2 212 ? 151.885 138.747 91.935  1.00 40.19  ? 158 GLY B C   1 
ATOM   6684  O  O   . GLY C 2 212 ? 152.727 138.363 91.122  1.00 45.95  ? 158 GLY B O   1 
ATOM   6685  N  N   . TYR C 2 213 ? 151.665 140.033 92.176  1.00 37.38  ? 159 TYR B N   1 
ATOM   6686  C  CA  . TYR C 2 213 ? 152.305 141.093 91.410  1.00 38.70  ? 159 TYR B CA  1 
ATOM   6687  C  C   . TYR C 2 213 ? 153.290 141.842 92.290  1.00 40.77  ? 159 TYR B C   1 
ATOM   6688  O  O   . TYR C 2 213 ? 152.928 142.307 93.373  1.00 43.03  ? 159 TYR B O   1 
ATOM   6689  C  CB  . TYR C 2 213 ? 151.265 142.062 90.847  1.00 40.52  ? 159 TYR B CB  1 
ATOM   6690  C  CG  . TYR C 2 213 ? 150.308 141.441 89.861  1.00 40.34  ? 159 TYR B CG  1 
ATOM   6691  C  CD1 . TYR C 2 213 ? 150.728 141.087 88.592  1.00 41.89  ? 159 TYR B CD1 1 
ATOM   6692  C  CD2 . TYR C 2 213 ? 148.983 141.225 90.193  1.00 38.44  ? 159 TYR B CD2 1 
ATOM   6693  C  CE1 . TYR C 2 213 ? 149.865 140.523 87.687  1.00 39.93  ? 159 TYR B CE1 1 
ATOM   6694  C  CE2 . TYR C 2 213 ? 148.111 140.661 89.290  1.00 38.02  ? 159 TYR B CE2 1 
ATOM   6695  C  CZ  . TYR C 2 213 ? 148.560 140.314 88.038  1.00 38.37  ? 159 TYR B CZ  1 
ATOM   6696  O  OH  . TYR C 2 213 ? 147.696 139.756 87.131  1.00 42.72  ? 159 TYR B OH  1 
ATOM   6697  N  N   . THR C 2 214 ? 154.528 141.963 91.822  1.00 41.56  ? 160 THR B N   1 
ATOM   6698  C  CA  . THR C 2 214 ? 155.542 142.689 92.565  1.00 39.73  ? 160 THR B CA  1 
ATOM   6699  C  C   . THR C 2 214 ? 155.420 144.183 92.289  1.00 41.67  ? 160 THR B C   1 
ATOM   6700  O  O   . THR C 2 214 ? 154.528 144.640 91.573  1.00 44.04  ? 160 THR B O   1 
ATOM   6701  C  CB  . THR C 2 214 ? 156.936 142.186 92.209  1.00 40.87  ? 160 THR B CB  1 
ATOM   6702  O  OG1 . THR C 2 214 ? 157.190 142.420 90.821  1.00 45.27  ? 160 THR B OG1 1 
ATOM   6703  C  CG2 . THR C 2 214 ? 157.053 140.707 92.492  1.00 39.51  ? 160 THR B CG2 1 
ATOM   6704  N  N   . THR C 2 215 ? 156.335 144.962 92.862  1.00 40.98  ? 161 THR B N   1 
ATOM   6705  C  CA  . THR C 2 215 ? 156.332 146.399 92.634  1.00 41.30  ? 161 THR B CA  1 
ATOM   6706  C  C   . THR C 2 215 ? 156.748 146.779 91.220  1.00 45.39  ? 161 THR B C   1 
ATOM   6707  O  O   . THR C 2 215 ? 156.607 147.947 90.847  1.00 48.32  ? 161 THR B O   1 
ATOM   6708  C  CB  . THR C 2 215 ? 157.237 147.093 93.647  1.00 41.08  ? 161 THR B CB  1 
ATOM   6709  O  OG1 . THR C 2 215 ? 158.428 146.323 93.826  1.00 45.50  ? 161 THR B OG1 1 
ATOM   6710  C  CG2 . THR C 2 215 ? 156.524 147.225 94.968  1.00 38.08  ? 161 THR B CG2 1 
ATOM   6711  N  N   . ASP C 2 216 ? 157.265 145.839 90.433  1.00 46.83  ? 162 ASP B N   1 
ATOM   6712  C  CA  . ASP C 2 216 ? 157.469 146.072 89.010  1.00 50.23  ? 162 ASP B CA  1 
ATOM   6713  C  C   . ASP C 2 216 ? 156.182 145.954 88.208  1.00 50.05  ? 162 ASP B C   1 
ATOM   6714  O  O   . ASP C 2 216 ? 156.174 146.311 87.027  1.00 53.14  ? 162 ASP B O   1 
ATOM   6715  C  CB  . ASP C 2 216 ? 158.497 145.087 88.456  1.00 54.79  ? 162 ASP B CB  1 
ATOM   6716  C  CG  . ASP C 2 216 ? 159.770 145.070 89.262  1.00 62.99  ? 162 ASP B CG  1 
ATOM   6717  O  OD1 . ASP C 2 216 ? 159.909 145.922 90.161  1.00 62.64  ? 162 ASP B OD1 1 
ATOM   6718  O  OD2 . ASP C 2 216 ? 160.631 144.204 89.005  1.00 66.30  ? 162 ASP B OD2 1 
ATOM   6719  N  N   . ASP C 2 217 ? 155.111 145.454 88.815  1.00 46.66  ? 163 ASP B N   1 
ATOM   6720  C  CA  . ASP C 2 217 ? 153.831 145.270 88.150  1.00 47.16  ? 163 ASP B CA  1 
ATOM   6721  C  C   . ASP C 2 217 ? 152.701 146.092 88.746  1.00 45.79  ? 163 ASP B C   1 
ATOM   6722  O  O   . ASP C 2 217 ? 151.825 146.528 88.004  1.00 49.26  ? 163 ASP B O   1 
ATOM   6723  C  CB  . ASP C 2 217 ? 153.416 143.793 88.188  1.00 45.64  ? 163 ASP B CB  1 
ATOM   6724  C  CG  . ASP C 2 217 ? 154.406 142.889 87.498  1.00 53.14  ? 163 ASP B CG  1 
ATOM   6725  O  OD1 . ASP C 2 217 ? 154.992 143.309 86.483  1.00 62.24  ? 163 ASP B OD1 1 
ATOM   6726  O  OD2 . ASP C 2 217 ? 154.595 141.750 87.969  1.00 51.72  ? 163 ASP B OD2 1 
ATOM   6727  N  N   . ILE C 2 218 ? 152.688 146.311 90.057  1.00 43.27  ? 164 ILE B N   1 
ATOM   6728  C  CA  . ILE C 2 218 ? 151.568 146.963 90.717  1.00 41.24  ? 164 ILE B CA  1 
ATOM   6729  C  C   . ILE C 2 218 ? 152.103 147.939 91.754  1.00 43.30  ? 164 ILE B C   1 
ATOM   6730  O  O   . ILE C 2 218 ? 153.190 147.755 92.306  1.00 47.83  ? 164 ILE B O   1 
ATOM   6731  C  CB  . ILE C 2 218 ? 150.619 145.922 91.355  1.00 36.49  ? 164 ILE B CB  1 
ATOM   6732  C  CG1 . ILE C 2 218 ? 149.232 146.506 91.581  1.00 36.42  ? 164 ILE B CG1 1 
ATOM   6733  C  CG2 . ILE C 2 218 ? 151.183 145.399 92.651  1.00 36.61  ? 164 ILE B CG2 1 
ATOM   6734  C  CD1 . ILE C 2 218 ? 148.177 145.464 91.752  1.00 37.32  ? 164 ILE B CD1 1 
ATOM   6735  N  N   . GLU C 2 219 ? 151.337 148.997 92.001  1.00 43.13  ? 165 GLU B N   1 
ATOM   6736  C  CA  . GLU C 2 219 ? 151.640 149.966 93.043  1.00 42.83  ? 165 GLU B CA  1 
ATOM   6737  C  C   . GLU C 2 219 ? 150.382 150.226 93.852  1.00 41.54  ? 165 GLU B C   1 
ATOM   6738  O  O   . GLU C 2 219 ? 149.277 150.221 93.309  1.00 44.16  ? 165 GLU B O   1 
ATOM   6739  C  CB  . GLU C 2 219 ? 152.164 151.282 92.466  1.00 46.09  ? 165 GLU B CB  1 
ATOM   6740  C  CG  . GLU C 2 219 ? 153.491 151.163 91.753  1.00 57.08  ? 165 GLU B CG  1 
ATOM   6741  C  CD  . GLU C 2 219 ? 154.050 152.509 91.338  1.00 71.10  ? 165 GLU B CD  1 
ATOM   6742  O  OE1 . GLU C 2 219 ? 153.503 153.540 91.778  1.00 72.35  ? 165 GLU B OE1 1 
ATOM   6743  O  OE2 . GLU C 2 219 ? 155.038 152.538 90.573  1.00 77.03  ? 165 GLU B OE2 1 
ATOM   6744  N  N   . PHE C 2 220 ? 150.555 150.450 95.148  1.00 36.17  ? 166 PHE B N   1 
ATOM   6745  C  CA  . PHE C 2 220 ? 149.458 150.736 96.057  1.00 34.24  ? 166 PHE B CA  1 
ATOM   6746  C  C   . PHE C 2 220 ? 149.649 152.114 96.666  1.00 37.02  ? 166 PHE B C   1 
ATOM   6747  O  O   . PHE C 2 220 ? 150.779 152.538 96.915  1.00 39.80  ? 166 PHE B O   1 
ATOM   6748  C  CB  . PHE C 2 220 ? 149.374 149.704 97.175  1.00 33.96  ? 166 PHE B CB  1 
ATOM   6749  C  CG  . PHE C 2 220 ? 148.744 148.416 96.768  1.00 35.90  ? 166 PHE B CG  1 
ATOM   6750  C  CD1 . PHE C 2 220 ? 148.223 148.247 95.505  1.00 38.28  ? 166 PHE B CD1 1 
ATOM   6751  C  CD2 . PHE C 2 220 ? 148.655 147.374 97.663  1.00 36.17  ? 166 PHE B CD2 1 
ATOM   6752  C  CE1 . PHE C 2 220 ? 147.635 147.060 95.139  1.00 36.83  ? 166 PHE B CE1 1 
ATOM   6753  C  CE2 . PHE C 2 220 ? 148.066 146.191 97.303  1.00 38.44  ? 166 PHE B CE2 1 
ATOM   6754  C  CZ  . PHE C 2 220 ? 147.556 146.033 96.040  1.00 37.16  ? 166 PHE B CZ  1 
ATOM   6755  N  N   . TYR C 2 221 ? 148.544 152.814 96.896  1.00 36.05  ? 167 TYR B N   1 
ATOM   6756  C  CA  . TYR C 2 221 ? 148.593 154.074 97.618  1.00 34.63  ? 167 TYR B CA  1 
ATOM   6757  C  C   . TYR C 2 221 ? 147.230 154.330 98.236  1.00 35.74  ? 167 TYR B C   1 
ATOM   6758  O  O   . TYR C 2 221 ? 146.222 153.766 97.809  1.00 37.25  ? 167 TYR B O   1 
ATOM   6759  C  CB  . TYR C 2 221 ? 149.015 155.233 96.710  1.00 30.88  ? 167 TYR B CB  1 
ATOM   6760  C  CG  . TYR C 2 221 ? 148.030 155.578 95.624  1.00 30.08  ? 167 TYR B CG  1 
ATOM   6761  C  CD1 . TYR C 2 221 ? 147.951 154.823 94.469  1.00 33.69  ? 167 TYR B CD1 1 
ATOM   6762  C  CD2 . TYR C 2 221 ? 147.197 156.672 95.745  1.00 31.50  ? 167 TYR B CD2 1 
ATOM   6763  C  CE1 . TYR C 2 221 ? 147.059 155.139 93.477  1.00 39.56  ? 167 TYR B CE1 1 
ATOM   6764  C  CE2 . TYR C 2 221 ? 146.302 156.996 94.759  1.00 35.59  ? 167 TYR B CE2 1 
ATOM   6765  C  CZ  . TYR C 2 221 ? 146.238 156.228 93.627  1.00 40.16  ? 167 TYR B CZ  1 
ATOM   6766  O  OH  . TYR C 2 221 ? 145.341 156.545 92.640  1.00 40.15  ? 167 TYR B OH  1 
ATOM   6767  N  N   . TRP C 2 222 ? 147.218 155.177 99.259  1.00 36.04  ? 168 TRP B N   1 
ATOM   6768  C  CA  . TRP C 2 222 ? 145.987 155.592 99.915  1.00 33.77  ? 168 TRP B CA  1 
ATOM   6769  C  C   . TRP C 2 222 ? 145.408 156.777 99.161  1.00 37.94  ? 168 TRP B C   1 
ATOM   6770  O  O   . TRP C 2 222 ? 146.035 157.838 99.096  1.00 43.28  ? 168 TRP B O   1 
ATOM   6771  C  CB  . TRP C 2 222 ? 146.237 155.980 101.370 1.00 34.45  ? 168 TRP B CB  1 
ATOM   6772  C  CG  . TRP C 2 222 ? 146.513 154.849 102.284 1.00 33.06  ? 168 TRP B CG  1 
ATOM   6773  C  CD1 . TRP C 2 222 ? 147.683 154.580 102.911 1.00 32.92  ? 168 TRP B CD1 1 
ATOM   6774  C  CD2 . TRP C 2 222 ? 145.595 153.837 102.698 1.00 33.79  ? 168 TRP B CD2 1 
ATOM   6775  N  NE1 . TRP C 2 222 ? 147.560 153.460 103.684 1.00 33.85  ? 168 TRP B NE1 1 
ATOM   6776  C  CE2 . TRP C 2 222 ? 146.283 152.985 103.571 1.00 32.31  ? 168 TRP B CE2 1 
ATOM   6777  C  CE3 . TRP C 2 222 ? 144.257 153.568 102.411 1.00 32.06  ? 168 TRP B CE3 1 
ATOM   6778  C  CZ2 . TRP C 2 222 ? 145.684 151.884 104.158 1.00 29.16  ? 168 TRP B CZ2 1 
ATOM   6779  C  CZ3 . TRP C 2 222 ? 143.667 152.476 102.992 1.00 30.54  ? 168 TRP B CZ3 1 
ATOM   6780  C  CH2 . TRP C 2 222 ? 144.378 151.646 103.857 1.00 28.97  ? 168 TRP B CH2 1 
ATOM   6781  N  N   . ARG C 2 223 ? 144.216 156.605 98.604  1.00 34.73  ? 169 ARG B N   1 
ATOM   6782  C  CA  . ARG C 2 223 ? 143.609 157.671 97.822  1.00 36.69  ? 169 ARG B CA  1 
ATOM   6783  C  C   . ARG C 2 223 ? 143.111 158.778 98.738  1.00 43.55  ? 169 ARG B C   1 
ATOM   6784  O  O   . ARG C 2 223 ? 142.309 158.537 99.644  1.00 41.23  ? 169 ARG B O   1 
ATOM   6785  C  CB  . ARG C 2 223 ? 142.463 157.127 96.981  1.00 34.13  ? 169 ARG B CB  1 
ATOM   6786  C  CG  . ARG C 2 223 ? 142.535 157.541 95.535  1.00 36.74  ? 169 ARG B CG  1 
ATOM   6787  C  CD  . ARG C 2 223 ? 141.475 156.854 94.713  1.00 42.61  ? 169 ARG B CD  1 
ATOM   6788  N  NE  . ARG C 2 223 ? 140.174 157.489 94.852  1.00 44.71  ? 169 ARG B NE  1 
ATOM   6789  C  CZ  . ARG C 2 223 ? 139.676 158.361 93.988  1.00 47.25  ? 169 ARG B CZ  1 
ATOM   6790  N  NH1 . ARG C 2 223 ? 140.343 158.715 92.903  1.00 43.96  ? 169 ARG B NH1 1 
ATOM   6791  N  NH2 . ARG C 2 223 ? 138.479 158.889 94.216  1.00 48.49  ? 169 ARG B NH2 1 
ATOM   6792  N  N   . GLY C 2 224 ? 143.578 159.995 98.495  1.00 44.97  ? 170 GLY B N   1 
ATOM   6793  C  CA  . GLY C 2 224 ? 143.251 161.107 99.353  1.00 44.36  ? 170 GLY B CA  1 
ATOM   6794  C  C   . GLY C 2 224 ? 144.140 161.256 100.563 1.00 47.69  ? 170 GLY B C   1 
ATOM   6795  O  O   . GLY C 2 224 ? 143.934 162.185 101.349 1.00 54.43  ? 170 GLY B O   1 
ATOM   6796  N  N   . GLY C 2 225 ? 145.115 160.373 100.745 1.00 42.86  ? 171 GLY B N   1 
ATOM   6797  C  CA  . GLY C 2 225 ? 146.049 160.504 101.843 1.00 44.43  ? 171 GLY B CA  1 
ATOM   6798  C  C   . GLY C 2 225 ? 145.480 160.088 103.180 1.00 48.35  ? 171 GLY B C   1 
ATOM   6799  O  O   . GLY C 2 225 ? 145.071 158.939 103.354 1.00 49.71  ? 171 GLY B O   1 
ATOM   6800  N  N   . ASP C 2 226 ? 145.461 161.013 104.141 1.00 51.70  ? 172 ASP B N   1 
ATOM   6801  C  CA  . ASP C 2 226 ? 144.930 160.697 105.460 1.00 53.81  ? 172 ASP B CA  1 
ATOM   6802  C  C   . ASP C 2 226 ? 143.417 160.573 105.456 1.00 52.31  ? 172 ASP B C   1 
ATOM   6803  O  O   . ASP C 2 226 ? 142.851 160.007 106.395 1.00 52.49  ? 172 ASP B O   1 
ATOM   6804  C  CB  . ASP C 2 226 ? 145.358 161.757 106.470 1.00 59.92  ? 172 ASP B CB  1 
ATOM   6805  C  CG  . ASP C 2 226 ? 146.862 161.843 106.614 1.00 73.41  ? 172 ASP B CG  1 
ATOM   6806  O  OD1 . ASP C 2 226 ? 147.534 160.800 106.481 1.00 73.22  ? 172 ASP B OD1 1 
ATOM   6807  O  OD2 . ASP C 2 226 ? 147.375 162.956 106.853 1.00 78.55  ? 172 ASP B OD2 1 
ATOM   6808  N  N   . LYS C 2 227 ? 142.754 161.077 104.424 1.00 49.92  ? 173 LYS B N   1 
ATOM   6809  C  CA  . LYS C 2 227 ? 141.311 160.978 104.304 1.00 50.42  ? 173 LYS B CA  1 
ATOM   6810  C  C   . LYS C 2 227 ? 140.874 159.731 103.555 1.00 48.73  ? 173 LYS B C   1 
ATOM   6811  O  O   . LYS C 2 227 ? 139.811 159.742 102.929 1.00 50.57  ? 173 LYS B O   1 
ATOM   6812  C  CB  . LYS C 2 227 ? 140.758 162.215 103.598 1.00 55.49  ? 173 LYS B CB  1 
ATOM   6813  C  CG  . LYS C 2 227 ? 141.353 163.525 104.065 1.00 57.43  ? 173 LYS B CG  1 
ATOM   6814  C  CD  . LYS C 2 227 ? 140.940 164.658 103.144 1.00 67.27  ? 173 LYS B CD  1 
ATOM   6815  C  CE  . LYS C 2 227 ? 141.720 165.931 103.429 1.00 76.92  ? 173 LYS B CE  1 
ATOM   6816  N  NZ  . LYS C 2 227 ? 141.345 167.024 102.491 1.00 84.22  ? 173 LYS B NZ  1 
ATOM   6817  N  N   . ALA C 2 228 ? 141.673 158.666 103.590 1.00 44.30  ? 174 ALA B N   1 
ATOM   6818  C  CA  . ALA C 2 228 ? 141.358 157.483 102.802 1.00 39.59  ? 174 ALA B CA  1 
ATOM   6819  C  C   . ALA C 2 228 ? 140.476 156.516 103.573 1.00 39.04  ? 174 ALA B C   1 
ATOM   6820  O  O   . ALA C 2 228 ? 139.862 155.624 102.981 1.00 41.21  ? 174 ALA B O   1 
ATOM   6821  C  CB  . ALA C 2 228 ? 142.644 156.793 102.361 1.00 38.35  ? 174 ALA B CB  1 
ATOM   6822  N  N   . VAL C 2 229 ? 140.410 156.664 104.891 1.00 38.85  ? 175 VAL B N   1 
ATOM   6823  C  CA  . VAL C 2 229 ? 139.650 155.772 105.754 1.00 35.43  ? 175 VAL B CA  1 
ATOM   6824  C  C   . VAL C 2 229 ? 138.637 156.599 106.529 1.00 37.10  ? 175 VAL B C   1 
ATOM   6825  O  O   . VAL C 2 229 ? 139.004 157.558 107.216 1.00 41.43  ? 175 VAL B O   1 
ATOM   6826  C  CB  . VAL C 2 229 ? 140.571 154.991 106.703 1.00 30.54  ? 175 VAL B CB  1 
ATOM   6827  C  CG1 . VAL C 2 229 ? 139.765 154.307 107.770 1.00 30.41  ? 175 VAL B CG1 1 
ATOM   6828  C  CG2 . VAL C 2 229 ? 141.367 153.978 105.924 1.00 27.90  ? 175 VAL B CG2 1 
ATOM   6829  N  N   . THR C 2 230 ? 137.364 156.232 106.416 1.00 34.31  ? 176 THR B N   1 
ATOM   6830  C  CA  . THR C 2 230 ? 136.291 156.954 107.076 1.00 37.15  ? 176 THR B CA  1 
ATOM   6831  C  C   . THR C 2 230 ? 135.457 155.986 107.897 1.00 37.66  ? 176 THR B C   1 
ATOM   6832  O  O   . THR C 2 230 ? 135.516 154.770 107.715 1.00 37.62  ? 176 THR B O   1 
ATOM   6833  C  CB  . THR C 2 230 ? 135.395 157.693 106.076 1.00 40.59  ? 176 THR B CB  1 
ATOM   6834  O  OG1 . THR C 2 230 ? 134.827 156.757 105.156 1.00 45.29  ? 176 THR B OG1 1 
ATOM   6835  C  CG2 . THR C 2 230 ? 136.193 158.723 105.305 1.00 37.34  ? 176 THR B CG2 1 
ATOM   6836  N  N   . GLY C 2 231 ? 134.683 156.540 108.818 1.00 38.47  ? 177 GLY B N   1 
ATOM   6837  C  CA  . GLY C 2 231 ? 133.817 155.741 109.650 1.00 37.61  ? 177 GLY B CA  1 
ATOM   6838  C  C   . GLY C 2 231 ? 134.409 155.288 110.960 1.00 40.53  ? 177 GLY B C   1 
ATOM   6839  O  O   . GLY C 2 231 ? 133.844 154.392 111.593 1.00 44.00  ? 177 GLY B O   1 
ATOM   6840  N  N   . VAL C 2 232 ? 135.527 155.870 111.391 1.00 42.32  ? 178 VAL B N   1 
ATOM   6841  C  CA  . VAL C 2 232 ? 136.095 155.501 112.682 1.00 42.52  ? 178 VAL B CA  1 
ATOM   6842  C  C   . VAL C 2 232 ? 135.168 155.914 113.816 1.00 44.83  ? 178 VAL B C   1 
ATOM   6843  O  O   . VAL C 2 232 ? 135.152 155.280 114.876 1.00 46.54  ? 178 VAL B O   1 
ATOM   6844  C  CB  . VAL C 2 232 ? 137.497 156.109 112.839 1.00 42.35  ? 178 VAL B CB  1 
ATOM   6845  C  CG1 . VAL C 2 232 ? 138.208 155.494 114.025 1.00 39.13  ? 178 VAL B CG1 1 
ATOM   6846  C  CG2 . VAL C 2 232 ? 138.296 155.889 111.578 1.00 41.55  ? 178 VAL B CG2 1 
ATOM   6847  N  N   . GLU C 2 233 ? 134.380 156.971 113.620 1.00 43.38  ? 179 GLU B N   1 
ATOM   6848  C  CA  . GLU C 2 233 ? 133.393 157.357 114.617 1.00 41.65  ? 179 GLU B CA  1 
ATOM   6849  C  C   . GLU C 2 233 ? 132.282 156.325 114.769 1.00 44.42  ? 179 GLU B C   1 
ATOM   6850  O  O   . GLU C 2 233 ? 131.589 156.333 115.789 1.00 50.77  ? 179 GLU B O   1 
ATOM   6851  C  CB  . GLU C 2 233 ? 132.788 158.713 114.261 1.00 41.38  ? 179 GLU B CB  1 
ATOM   6852  C  CG  . GLU C 2 233 ? 131.984 158.716 112.982 1.00 48.33  ? 179 GLU B CG  1 
ATOM   6853  C  CD  . GLU C 2 233 ? 132.844 158.795 111.739 1.00 54.59  ? 179 GLU B CD  1 
ATOM   6854  O  OE1 . GLU C 2 233 ? 134.075 158.955 111.874 1.00 55.05  ? 179 GLU B OE1 1 
ATOM   6855  O  OE2 . GLU C 2 233 ? 132.287 158.703 110.625 1.00 54.47  ? 179 GLU B OE2 1 
ATOM   6856  N  N   . ARG C 2 234 ? 132.088 155.445 113.785 1.00 42.91  ? 180 ARG B N   1 
ATOM   6857  C  CA  . ARG C 2 234 ? 131.051 154.427 113.883 1.00 43.39  ? 180 ARG B CA  1 
ATOM   6858  C  C   . ARG C 2 234 ? 131.439 153.274 114.794 1.00 45.36  ? 180 ARG B C   1 
ATOM   6859  O  O   . ARG C 2 234 ? 130.563 152.511 115.210 1.00 52.30  ? 180 ARG B O   1 
ATOM   6860  C  CB  . ARG C 2 234 ? 130.709 153.868 112.502 1.00 39.30  ? 180 ARG B CB  1 
ATOM   6861  C  CG  . ARG C 2 234 ? 130.193 154.886 111.512 1.00 38.65  ? 180 ARG B CG  1 
ATOM   6862  C  CD  . ARG C 2 234 ? 129.596 154.192 110.306 1.00 38.60  ? 180 ARG B CD  1 
ATOM   6863  N  NE  . ARG C 2 234 ? 129.371 155.114 109.202 1.00 45.43  ? 180 ARG B NE  1 
ATOM   6864  C  CZ  . ARG C 2 234 ? 130.134 155.189 108.122 1.00 46.48  ? 180 ARG B CZ  1 
ATOM   6865  N  NH1 . ARG C 2 234 ? 131.168 154.385 107.949 1.00 41.62  ? 180 ARG B NH1 1 
ATOM   6866  N  NH2 . ARG C 2 234 ? 129.852 156.092 107.190 1.00 48.35  ? 180 ARG B NH2 1 
ATOM   6867  N  N   . ILE C 2 235 ? 132.723 153.122 115.106 1.00 43.59  ? 181 ILE B N   1 
ATOM   6868  C  CA  . ILE C 2 235 ? 133.175 152.004 115.922 1.00 43.69  ? 181 ILE B CA  1 
ATOM   6869  C  C   . ILE C 2 235 ? 132.754 152.244 117.364 1.00 49.44  ? 181 ILE B C   1 
ATOM   6870  O  O   . ILE C 2 235 ? 133.141 153.242 117.980 1.00 52.25  ? 181 ILE B O   1 
ATOM   6871  C  CB  . ILE C 2 235 ? 134.692 151.826 115.808 1.00 38.44  ? 181 ILE B CB  1 
ATOM   6872  C  CG1 . ILE C 2 235 ? 135.077 151.485 114.371 1.00 39.38  ? 181 ILE B CG1 1 
ATOM   6873  C  CG2 . ILE C 2 235 ? 135.162 150.750 116.750 1.00 39.56  ? 181 ILE B CG2 1 
ATOM   6874  C  CD1 . ILE C 2 235 ? 136.542 151.638 114.081 1.00 38.22  ? 181 ILE B CD1 1 
ATOM   6875  N  N   . GLU C 2 236 ? 131.958 151.326 117.910 1.00 50.10  ? 182 GLU B N   1 
ATOM   6876  C  CA  . GLU C 2 236 ? 131.429 151.442 119.268 1.00 48.88  ? 182 GLU B CA  1 
ATOM   6877  C  C   . GLU C 2 236 ? 131.699 150.140 120.010 1.00 47.84  ? 182 GLU B C   1 
ATOM   6878  O  O   . GLU C 2 236 ? 130.868 149.231 120.018 1.00 53.28  ? 182 GLU B O   1 
ATOM   6879  C  CB  . GLU C 2 236 ? 129.949 151.779 119.248 1.00 53.22  ? 182 GLU B CB  1 
ATOM   6880  C  CG  . GLU C 2 236 ? 129.654 153.194 118.803 1.00 60.57  ? 182 GLU B CG  1 
ATOM   6881  C  CD  . GLU C 2 236 ? 128.196 153.564 118.954 1.00 79.78  ? 182 GLU B CD  1 
ATOM   6882  O  OE1 . GLU C 2 236 ? 127.504 152.936 119.781 1.00 86.41  ? 182 GLU B OE1 1 
ATOM   6883  O  OE2 . GLU C 2 236 ? 127.740 154.482 118.242 1.00 85.85  ? 182 GLU B OE2 1 
ATOM   6884  N  N   . LEU C 2 237 ? 132.844 150.057 120.624 1.00 45.96  ? 183 LEU B N   1 
ATOM   6885  C  CA  . LEU C 2 237 ? 133.195 148.901 121.434 1.00 46.60  ? 183 LEU B CA  1 
ATOM   6886  C  C   . LEU C 2 237 ? 132.745 149.123 122.868 1.00 49.58  ? 183 LEU B C   1 
ATOM   6887  O  O   . LEU C 2 237 ? 133.012 150.188 123.434 1.00 51.88  ? 183 LEU B O   1 
ATOM   6888  C  CB  . LEU C 2 237 ? 134.691 148.650 121.396 1.00 46.13  ? 183 LEU B CB  1 
ATOM   6889  C  CG  . LEU C 2 237 ? 135.218 148.192 120.044 1.00 39.79  ? 183 LEU B CG  1 
ATOM   6890  C  CD1 . LEU C 2 237 ? 136.717 148.081 120.068 1.00 36.73  ? 183 LEU B CD1 1 
ATOM   6891  C  CD2 . LEU C 2 237 ? 134.597 146.869 119.693 1.00 41.10  ? 183 LEU B CD2 1 
ATOM   6892  N  N   . PRO C 2 238 ? 132.041 148.167 123.474 1.00 51.48  ? 184 PRO B N   1 
ATOM   6893  C  CA  . PRO C 2 238 ? 131.645 148.339 124.878 1.00 51.02  ? 184 PRO B CA  1 
ATOM   6894  C  C   . PRO C 2 238 ? 132.821 148.472 125.825 1.00 51.92  ? 184 PRO B C   1 
ATOM   6895  O  O   . PRO C 2 238 ? 132.728 149.211 126.811 1.00 53.55  ? 184 PRO B O   1 
ATOM   6896  C  CB  . PRO C 2 238 ? 130.836 147.068 125.162 1.00 48.50  ? 184 PRO B CB  1 
ATOM   6897  C  CG  . PRO C 2 238 ? 131.380 146.066 124.206 1.00 47.17  ? 184 PRO B CG  1 
ATOM   6898  C  CD  . PRO C 2 238 ? 131.674 146.840 122.958 1.00 52.32  ? 184 PRO B CD  1 
ATOM   6899  N  N   . GLN C 2 239 ? 133.935 147.797 125.545 1.00 49.99  ? 185 GLN B N   1 
ATOM   6900  C  CA  . GLN C 2 239 ? 135.025 147.675 126.499 1.00 48.49  ? 185 GLN B CA  1 
ATOM   6901  C  C   . GLN C 2 239 ? 136.254 148.501 126.151 1.00 50.79  ? 185 GLN B C   1 
ATOM   6902  O  O   . GLN C 2 239 ? 137.072 148.757 127.036 1.00 52.53  ? 185 GLN B O   1 
ATOM   6903  C  CB  . GLN C 2 239 ? 135.432 146.202 126.632 1.00 47.55  ? 185 GLN B CB  1 
ATOM   6904  C  CG  . GLN C 2 239 ? 136.123 145.856 127.928 1.00 55.14  ? 185 GLN B CG  1 
ATOM   6905  C  CD  . GLN C 2 239 ? 135.886 144.421 128.347 1.00 70.15  ? 185 GLN B CD  1 
ATOM   6906  O  OE1 . GLN C 2 239 ? 136.397 143.966 129.370 1.00 73.19  ? 185 GLN B OE1 1 
ATOM   6907  N  NE2 . GLN C 2 239 ? 135.101 143.700 127.560 1.00 73.66  ? 185 GLN B NE2 1 
ATOM   6908  N  N   . PHE C 2 240 ? 136.404 148.922 124.904 1.00 50.79  ? 186 PHE B N   1 
ATOM   6909  C  CA  . PHE C 2 240 ? 137.552 149.691 124.450 1.00 44.97  ? 186 PHE B CA  1 
ATOM   6910  C  C   . PHE C 2 240 ? 137.095 151.068 123.992 1.00 45.69  ? 186 PHE B C   1 
ATOM   6911  O  O   . PHE C 2 240 ? 135.906 151.374 123.968 1.00 52.26  ? 186 PHE B O   1 
ATOM   6912  C  CB  . PHE C 2 240 ? 138.278 148.972 123.314 1.00 40.33  ? 186 PHE B CB  1 
ATOM   6913  C  CG  . PHE C 2 240 ? 139.043 147.763 123.746 1.00 43.10  ? 186 PHE B CG  1 
ATOM   6914  C  CD1 . PHE C 2 240 ? 138.449 146.522 123.764 1.00 42.71  ? 186 PHE B CD1 1 
ATOM   6915  C  CD2 . PHE C 2 240 ? 140.368 147.867 124.112 1.00 43.72  ? 186 PHE B CD2 1 
ATOM   6916  C  CE1 . PHE C 2 240 ? 139.158 145.415 124.146 1.00 44.08  ? 186 PHE B CE1 1 
ATOM   6917  C  CE2 . PHE C 2 240 ? 141.078 146.765 124.499 1.00 42.19  ? 186 PHE B CE2 1 
ATOM   6918  C  CZ  . PHE C 2 240 ? 140.474 145.537 124.516 1.00 44.05  ? 186 PHE B CZ  1 
ATOM   6919  N  N   . SER C 2 241 ? 138.061 151.901 123.624 1.00 44.80  ? 187 SER B N   1 
ATOM   6920  C  CA  . SER C 2 241 ? 137.767 153.195 123.022 1.00 47.29  ? 187 SER B CA  1 
ATOM   6921  C  C   . SER C 2 241 ? 138.896 153.542 122.068 1.00 46.04  ? 187 SER B C   1 
ATOM   6922  O  O   . SER C 2 241 ? 140.054 153.613 122.486 1.00 45.27  ? 187 SER B O   1 
ATOM   6923  C  CB  . SER C 2 241 ? 137.611 154.280 124.082 1.00 48.68  ? 187 SER B CB  1 
ATOM   6924  O  OG  . SER C 2 241 ? 138.873 154.742 124.521 1.00 50.48  ? 187 SER B OG  1 
ATOM   6925  N  N   . ILE C 2 242 ? 138.559 153.759 120.798 1.00 43.59  ? 188 ILE B N   1 
ATOM   6926  C  CA  . ILE C 2 242 ? 139.571 154.058 119.794 1.00 41.41  ? 188 ILE B CA  1 
ATOM   6927  C  C   . ILE C 2 242 ? 140.245 155.376 120.136 1.00 44.55  ? 188 ILE B C   1 
ATOM   6928  O  O   . ILE C 2 242 ? 139.584 156.410 120.282 1.00 49.14  ? 188 ILE B O   1 
ATOM   6929  C  CB  . ILE C 2 242 ? 138.951 154.106 118.398 1.00 40.53  ? 188 ILE B CB  1 
ATOM   6930  C  CG1 . ILE C 2 242 ? 138.384 152.744 118.013 1.00 41.64  ? 188 ILE B CG1 1 
ATOM   6931  C  CG2 . ILE C 2 242 ? 139.986 154.555 117.386 1.00 40.13  ? 188 ILE B CG2 1 
ATOM   6932  C  CD1 . ILE C 2 242 ? 139.384 151.836 117.374 1.00 42.01  ? 188 ILE B CD1 1 
ATOM   6933  N  N   . VAL C 2 243 ? 141.566 155.350 120.252 1.00 43.47  ? 189 VAL B N   1 
ATOM   6934  C  CA  . VAL C 2 243 ? 142.324 156.561 120.531 1.00 42.66  ? 189 VAL B CA  1 
ATOM   6935  C  C   . VAL C 2 243 ? 142.802 157.220 119.248 1.00 49.55  ? 189 VAL B C   1 
ATOM   6936  O  O   . VAL C 2 243 ? 142.694 158.437 119.089 1.00 56.77  ? 189 VAL B O   1 
ATOM   6937  C  CB  . VAL C 2 243 ? 143.503 156.233 121.462 1.00 43.60  ? 189 VAL B CB  1 
ATOM   6938  C  CG1 . VAL C 2 243 ? 144.393 157.446 121.626 1.00 44.41  ? 189 VAL B CG1 1 
ATOM   6939  C  CG2 . VAL C 2 243 ? 142.997 155.766 122.802 1.00 46.37  ? 189 VAL B CG2 1 
ATOM   6940  N  N   . GLU C 2 244 ? 143.324 156.428 118.318 1.00 50.00  ? 190 GLU B N   1 
ATOM   6941  C  CA  . GLU C 2 244 ? 143.949 156.959 117.119 1.00 46.95  ? 190 GLU B CA  1 
ATOM   6942  C  C   . GLU C 2 244 ? 143.919 155.880 116.051 1.00 46.53  ? 190 GLU B C   1 
ATOM   6943  O  O   . GLU C 2 244 ? 143.833 154.691 116.356 1.00 49.80  ? 190 GLU B O   1 
ATOM   6944  C  CB  . GLU C 2 244 ? 145.385 157.399 117.413 1.00 49.42  ? 190 GLU B CB  1 
ATOM   6945  C  CG  . GLU C 2 244 ? 146.072 158.157 116.310 1.00 57.92  ? 190 GLU B CG  1 
ATOM   6946  C  CD  . GLU C 2 244 ? 147.553 158.298 116.567 1.00 68.48  ? 190 GLU B CD  1 
ATOM   6947  O  OE1 . GLU C 2 244 ? 148.073 157.564 117.431 1.00 67.94  ? 190 GLU B OE1 1 
ATOM   6948  O  OE2 . GLU C 2 244 ? 148.198 159.141 115.909 1.00 73.30  ? 190 GLU B OE2 1 
ATOM   6949  N  N   . HIS C 2 245 ? 143.981 156.307 114.795 1.00 43.38  ? 191 HIS B N   1 
ATOM   6950  C  CA  . HIS C 2 245 ? 144.187 155.399 113.679 1.00 41.74  ? 191 HIS B CA  1 
ATOM   6951  C  C   . HIS C 2 245 ? 145.267 155.972 112.775 1.00 42.12  ? 191 HIS B C   1 
ATOM   6952  O  O   . HIS C 2 245 ? 145.460 157.186 112.710 1.00 44.29  ? 191 HIS B O   1 
ATOM   6953  C  CB  . HIS C 2 245 ? 142.893 155.143 112.893 1.00 37.87  ? 191 HIS B CB  1 
ATOM   6954  C  CG  . HIS C 2 245 ? 142.552 156.214 111.907 1.00 44.31  ? 191 HIS B CG  1 
ATOM   6955  N  ND1 . HIS C 2 245 ? 141.841 157.343 112.249 1.00 47.64  ? 191 HIS B ND1 1 
ATOM   6956  C  CD2 . HIS C 2 245 ? 142.792 156.310 110.579 1.00 43.49  ? 191 HIS B CD2 1 
ATOM   6957  C  CE1 . HIS C 2 245 ? 141.674 158.097 111.179 1.00 45.86  ? 191 HIS B CE1 1 
ATOM   6958  N  NE2 . HIS C 2 245 ? 142.245 157.494 110.153 1.00 44.20  ? 191 HIS B NE2 1 
ATOM   6959  N  N   . ARG C 2 246 ? 145.984 155.083 112.092 1.00 40.71  ? 192 ARG B N   1 
ATOM   6960  C  CA  . ARG C 2 246 ? 147.163 155.470 111.333 1.00 38.71  ? 192 ARG B CA  1 
ATOM   6961  C  C   . ARG C 2 246 ? 147.236 154.697 110.026 1.00 38.46  ? 192 ARG B C   1 
ATOM   6962  O  O   . ARG C 2 246 ? 146.896 153.512 109.977 1.00 39.25  ? 192 ARG B O   1 
ATOM   6963  C  CB  . ARG C 2 246 ? 148.430 155.233 112.155 1.00 42.99  ? 192 ARG B CB  1 
ATOM   6964  C  CG  . ARG C 2 246 ? 149.640 156.008 111.687 1.00 46.45  ? 192 ARG B CG  1 
ATOM   6965  C  CD  . ARG C 2 246 ? 150.752 155.904 112.705 1.00 51.82  ? 192 ARG B CD  1 
ATOM   6966  N  NE  . ARG C 2 246 ? 150.309 156.331 114.025 1.00 55.07  ? 192 ARG B NE  1 
ATOM   6967  C  CZ  . ARG C 2 246 ? 151.045 156.255 115.125 1.00 56.97  ? 192 ARG B CZ  1 
ATOM   6968  N  NH1 . ARG C 2 246 ? 152.270 155.764 115.103 1.00 58.51  ? 192 ARG B NH1 1 
ATOM   6969  N  NH2 . ARG C 2 246 ? 150.537 156.684 116.275 1.00 54.57  ? 192 ARG B NH2 1 
ATOM   6970  N  N   . LEU C 2 247 ? 147.698 155.374 108.974 1.00 40.00  ? 193 LEU B N   1 
ATOM   6971  C  CA  . LEU C 2 247 ? 147.839 154.805 107.640 1.00 35.95  ? 193 LEU B CA  1 
ATOM   6972  C  C   . LEU C 2 247 ? 149.310 154.748 107.256 1.00 35.69  ? 193 LEU B C   1 
ATOM   6973  O  O   . LEU C 2 247 ? 150.029 155.741 107.398 1.00 39.25  ? 193 LEU B O   1 
ATOM   6974  C  CB  . LEU C 2 247 ? 147.074 155.631 106.608 1.00 34.00  ? 193 LEU B CB  1 
ATOM   6975  C  CG  . LEU C 2 247 ? 145.583 155.864 106.821 1.00 35.33  ? 193 LEU B CG  1 
ATOM   6976  C  CD1 . LEU C 2 247 ? 145.006 156.565 105.624 1.00 33.97  ? 193 LEU B CD1 1 
ATOM   6977  C  CD2 . LEU C 2 247 ? 144.887 154.556 107.049 1.00 33.51  ? 193 LEU B CD2 1 
ATOM   6978  N  N   . VAL C 2 248 ? 149.755 153.591 106.766 1.00 36.02  ? 194 VAL B N   1 
ATOM   6979  C  CA  . VAL C 2 248 ? 151.153 153.356 106.424 1.00 36.20  ? 194 VAL B CA  1 
ATOM   6980  C  C   . VAL C 2 248 ? 151.232 152.758 105.027 1.00 38.20  ? 194 VAL B C   1 
ATOM   6981  O  O   . VAL C 2 248 ? 150.388 151.942 104.644 1.00 38.70  ? 194 VAL B O   1 
ATOM   6982  C  CB  . VAL C 2 248 ? 151.840 152.419 107.438 1.00 36.95  ? 194 VAL B CB  1 
ATOM   6983  C  CG1 . VAL C 2 248 ? 153.337 152.418 107.227 1.00 41.35  ? 194 VAL B CG1 1 
ATOM   6984  C  CG2 . VAL C 2 248 ? 151.501 152.812 108.856 1.00 40.94  ? 194 VAL B CG2 1 
ATOM   6985  N  N   . SER C 2 249 ? 152.249 153.162 104.271 1.00 37.97  ? 195 SER B N   1 
ATOM   6986  C  CA  . SER C 2 249 ? 152.539 152.624 102.948 1.00 37.21  ? 195 SER B CA  1 
ATOM   6987  C  C   . SER C 2 249 ? 153.998 152.197 102.913 1.00 42.76  ? 195 SER B C   1 
ATOM   6988  O  O   . SER C 2 249 ? 154.873 152.970 103.310 1.00 51.67  ? 195 SER B O   1 
ATOM   6989  C  CB  . SER C 2 249 ? 152.255 153.672 101.869 1.00 34.24  ? 195 SER B CB  1 
ATOM   6990  O  OG  . SER C 2 249 ? 152.513 153.168 100.577 1.00 38.02  ? 195 SER B OG  1 
ATOM   6991  N  N   . ARG C 2 250 ? 154.271 150.981 102.443 1.00 41.04  ? 196 ARG B N   1 
ATOM   6992  C  CA  . ARG C 2 250 ? 155.638 150.471 102.467 1.00 42.31  ? 196 ARG B CA  1 
ATOM   6993  C  C   . ARG C 2 250 ? 155.784 149.332 101.463 1.00 43.54  ? 196 ARG B C   1 
ATOM   6994  O  O   . ARG C 2 250 ? 154.851 148.996 100.730 1.00 46.93  ? 196 ARG B O   1 
ATOM   6995  C  CB  . ARG C 2 250 ? 156.021 150.026 103.879 1.00 44.52  ? 196 ARG B CB  1 
ATOM   6996  C  CG  . ARG C 2 250 ? 154.983 149.147 104.534 1.00 40.95  ? 196 ARG B CG  1 
ATOM   6997  C  CD  . ARG C 2 250 ? 155.281 148.935 105.997 1.00 47.31  ? 196 ARG B CD  1 
ATOM   6998  N  NE  . ARG C 2 250 ? 156.434 148.068 106.193 1.00 55.68  ? 196 ARG B NE  1 
ATOM   6999  C  CZ  . ARG C 2 250 ? 156.355 146.780 106.491 1.00 55.30  ? 196 ARG B CZ  1 
ATOM   7000  N  NH1 . ARG C 2 250 ? 155.191 146.178 106.650 1.00 50.53  ? 196 ARG B NH1 1 
ATOM   7001  N  NH2 . ARG C 2 250 ? 157.474 146.079 106.633 1.00 55.28  ? 196 ARG B NH2 1 
ATOM   7002  N  N   . ASN C 2 251 ? 156.981 148.749 101.428 1.00 41.99  ? 197 ASN B N   1 
ATOM   7003  C  CA  . ASN C 2 251 ? 157.304 147.602 100.592 1.00 38.64  ? 197 ASN B CA  1 
ATOM   7004  C  C   . ASN C 2 251 ? 157.776 146.458 101.473 1.00 42.42  ? 197 ASN B C   1 
ATOM   7005  O  O   . ASN C 2 251 ? 158.552 146.667 102.408 1.00 50.81  ? 197 ASN B O   1 
ATOM   7006  C  CB  . ASN C 2 251 ? 158.400 147.928 99.572  1.00 36.58  ? 197 ASN B CB  1 
ATOM   7007  C  CG  . ASN C 2 251 ? 157.903 148.770 98.422  1.00 44.30  ? 197 ASN B CG  1 
ATOM   7008  O  OD1 . ASN C 2 251 ? 156.716 148.798 98.125  1.00 47.25  ? 197 ASN B OD1 1 
ATOM   7009  N  ND2 . ASN C 2 251 ? 158.819 149.449 97.754  1.00 47.06  ? 197 ASN B ND2 1 
ATOM   7010  N  N   . VAL C 2 252 ? 157.324 145.248 101.164 1.00 40.40  ? 198 VAL B N   1 
ATOM   7011  C  CA  . VAL C 2 252 ? 157.682 144.055 101.919 1.00 39.24  ? 198 VAL B CA  1 
ATOM   7012  C  C   . VAL C 2 252 ? 158.375 143.087 100.976 1.00 40.34  ? 198 VAL B C   1 
ATOM   7013  O  O   . VAL C 2 252 ? 157.854 142.789 99.899  1.00 42.75  ? 198 VAL B O   1 
ATOM   7014  C  CB  . VAL C 2 252 ? 156.450 143.401 102.564 1.00 40.30  ? 198 VAL B CB  1 
ATOM   7015  C  CG1 . VAL C 2 252 ? 156.858 142.166 103.323 1.00 40.98  ? 198 VAL B CG1 1 
ATOM   7016  C  CG2 . VAL C 2 252 ? 155.771 144.378 103.490 1.00 40.61  ? 198 VAL B CG2 1 
ATOM   7017  N  N   . VAL C 2 253 ? 159.538 142.591 101.379 1.00 41.21  ? 199 VAL B N   1 
ATOM   7018  C  CA  . VAL C 2 253 ? 160.347 141.721 100.536 1.00 40.63  ? 199 VAL B CA  1 
ATOM   7019  C  C   . VAL C 2 253 ? 160.213 140.288 101.023 1.00 41.45  ? 199 VAL B C   1 
ATOM   7020  O  O   . VAL C 2 253 ? 160.455 139.999 102.200 1.00 43.44  ? 199 VAL B O   1 
ATOM   7021  C  CB  . VAL C 2 253 ? 161.820 142.158 100.534 1.00 38.69  ? 199 VAL B CB  1 
ATOM   7022  C  CG1 . VAL C 2 253 ? 162.602 141.352 99.522  1.00 34.48  ? 199 VAL B CG1 1 
ATOM   7023  C  CG2 . VAL C 2 253 ? 161.928 143.632 100.234 1.00 40.52  ? 199 VAL B CG2 1 
ATOM   7024  N  N   . PHE C 2 254 ? 159.827 139.396 100.124 1.00 39.21  ? 200 PHE B N   1 
ATOM   7025  C  CA  . PHE C 2 254 ? 159.840 137.961 100.341 1.00 40.61  ? 200 PHE B CA  1 
ATOM   7026  C  C   . PHE C 2 254 ? 160.812 137.322 99.355  1.00 45.56  ? 200 PHE B C   1 
ATOM   7027  O  O   . PHE C 2 254 ? 161.373 137.987 98.482  1.00 48.58  ? 200 PHE B O   1 
ATOM   7028  C  CB  . PHE C 2 254 ? 158.443 137.361 100.176 1.00 39.73  ? 200 PHE B CB  1 
ATOM   7029  C  CG  . PHE C 2 254 ? 157.432 137.896 101.140 1.00 40.37  ? 200 PHE B CG  1 
ATOM   7030  C  CD1 . PHE C 2 254 ? 157.536 137.632 102.487 1.00 38.50  ? 200 PHE B CD1 1 
ATOM   7031  C  CD2 . PHE C 2 254 ? 156.365 138.647 100.696 1.00 40.08  ? 200 PHE B CD2 1 
ATOM   7032  C  CE1 . PHE C 2 254 ? 156.604 138.115 103.368 1.00 38.34  ? 200 PHE B CE1 1 
ATOM   7033  C  CE2 . PHE C 2 254 ? 155.435 139.127 101.576 1.00 41.75  ? 200 PHE B CE2 1 
ATOM   7034  C  CZ  . PHE C 2 254 ? 155.554 138.864 102.913 1.00 41.95  ? 200 PHE B CZ  1 
ATOM   7035  N  N   . ALA C 2 255 ? 160.971 136.003 99.476  1.00 45.75  ? 201 ALA B N   1 
ATOM   7036  C  CA  . ALA C 2 255 ? 161.913 135.283 98.629  1.00 44.71  ? 201 ALA B CA  1 
ATOM   7037  C  C   . ALA C 2 255 ? 161.573 135.400 97.153  1.00 45.13  ? 201 ALA B C   1 
ATOM   7038  O  O   . ALA C 2 255 ? 162.440 135.151 96.310  1.00 48.80  ? 201 ALA B O   1 
ATOM   7039  C  CB  . ALA C 2 255 ? 161.966 133.809 99.028  1.00 39.95  ? 201 ALA B CB  1 
ATOM   7040  N  N   . THR C 2 256 ? 160.339 135.767 96.819  1.00 43.54  ? 202 THR B N   1 
ATOM   7041  C  CA  . THR C 2 256 ? 159.919 135.907 95.435  1.00 42.08  ? 202 THR B CA  1 
ATOM   7042  C  C   . THR C 2 256 ? 159.908 137.350 94.940  1.00 42.83  ? 202 THR B C   1 
ATOM   7043  O  O   . THR C 2 256 ? 159.563 137.582 93.779  1.00 43.47  ? 202 THR B O   1 
ATOM   7044  C  CB  . THR C 2 256 ? 158.534 135.283 95.240  1.00 39.48  ? 202 THR B CB  1 
ATOM   7045  O  OG1 . THR C 2 256 ? 157.594 135.903 96.122  1.00 41.38  ? 202 THR B OG1 1 
ATOM   7046  C  CG2 . THR C 2 256 ? 158.582 133.798 95.527  1.00 36.63  ? 202 THR B CG2 1 
ATOM   7047  N  N   . GLY C 2 257 ? 160.276 138.319 95.769  1.00 41.62  ? 203 GLY B N   1 
ATOM   7048  C  CA  . GLY C 2 257 ? 160.379 139.686 95.308  1.00 40.35  ? 203 GLY B CA  1 
ATOM   7049  C  C   . GLY C 2 257 ? 159.775 140.653 96.299  1.00 40.54  ? 203 GLY B C   1 
ATOM   7050  O  O   . GLY C 2 257 ? 159.442 140.298 97.424  1.00 43.08  ? 203 GLY B O   1 
ATOM   7051  N  N   . ALA C 2 258 ? 159.624 141.900 95.866  1.00 37.97  ? 204 ALA B N   1 
ATOM   7052  C  CA  . ALA C 2 258 ? 159.135 142.978 96.716  1.00 37.32  ? 204 ALA B CA  1 
ATOM   7053  C  C   . ALA C 2 258 ? 157.711 143.342 96.324  1.00 38.34  ? 204 ALA B C   1 
ATOM   7054  O  O   . ALA C 2 258 ? 157.418 143.526 95.142  1.00 43.70  ? 204 ALA B O   1 
ATOM   7055  C  CB  . ALA C 2 258 ? 160.038 144.206 96.609  1.00 36.43  ? 204 ALA B CB  1 
ATOM   7056  N  N   . TYR C 2 259 ? 156.839 143.465 97.316  1.00 36.24  ? 205 TYR B N   1 
ATOM   7057  C  CA  . TYR C 2 259 ? 155.429 143.699 97.085  1.00 36.81  ? 205 TYR B CA  1 
ATOM   7058  C  C   . TYR C 2 259 ? 154.967 144.948 97.821  1.00 39.88  ? 205 TYR B C   1 
ATOM   7059  O  O   . TYR C 2 259 ? 155.461 145.253 98.910  1.00 43.43  ? 205 TYR B O   1 
ATOM   7060  C  CB  . TYR C 2 259 ? 154.593 142.500 97.548  1.00 36.58  ? 205 TYR B CB  1 
ATOM   7061  C  CG  . TYR C 2 259 ? 155.023 141.189 96.941  1.00 39.37  ? 205 TYR B CG  1 
ATOM   7062  C  CD1 . TYR C 2 259 ? 154.492 140.748 95.744  1.00 37.73  ? 205 TYR B CD1 1 
ATOM   7063  C  CD2 . TYR C 2 259 ? 155.967 140.394 97.564  1.00 38.28  ? 205 TYR B CD2 1 
ATOM   7064  C  CE1 . TYR C 2 259 ? 154.888 139.558 95.190  1.00 36.96  ? 205 TYR B CE1 1 
ATOM   7065  C  CE2 . TYR C 2 259 ? 156.365 139.205 97.016  1.00 39.17  ? 205 TYR B CE2 1 
ATOM   7066  C  CZ  . TYR C 2 259 ? 155.825 138.792 95.830  1.00 38.40  ? 205 TYR B CZ  1 
ATOM   7067  O  OH  . TYR C 2 259 ? 156.227 137.599 95.289  1.00 42.25  ? 205 TYR B OH  1 
ATOM   7068  N  N   . PRO C 2 260 ? 154.026 145.690 97.248  1.00 40.33  ? 206 PRO B N   1 
ATOM   7069  C  CA  . PRO C 2 260 ? 153.469 146.849 97.946  1.00 37.09  ? 206 PRO B CA  1 
ATOM   7070  C  C   . PRO C 2 260 ? 152.652 146.417 99.149  1.00 37.26  ? 206 PRO B C   1 
ATOM   7071  O  O   . PRO C 2 260 ? 152.115 145.311 99.205  1.00 40.70  ? 206 PRO B O   1 
ATOM   7072  C  CB  . PRO C 2 260 ? 152.585 147.504 96.884  1.00 37.25  ? 206 PRO B CB  1 
ATOM   7073  C  CG  . PRO C 2 260 ? 152.216 146.388 95.983  1.00 35.71  ? 206 PRO B CG  1 
ATOM   7074  C  CD  . PRO C 2 260 ? 153.412 145.502 95.925  1.00 38.36  ? 206 PRO B CD  1 
ATOM   7075  N  N   . ARG C 2 261 ? 152.554 147.316 100.123 1.00 34.39  ? 207 ARG B N   1 
ATOM   7076  C  CA  . ARG C 2 261 ? 151.830 147.011 101.345 1.00 32.98  ? 207 ARG B CA  1 
ATOM   7077  C  C   . ARG C 2 261 ? 151.217 148.287 101.895 1.00 35.48  ? 207 ARG B C   1 
ATOM   7078  O  O   . ARG C 2 261 ? 151.914 149.289 102.068 1.00 39.04  ? 207 ARG B O   1 
ATOM   7079  C  CB  . ARG C 2 261 ? 152.761 146.374 102.377 1.00 33.49  ? 207 ARG B CB  1 
ATOM   7080  C  CG  . ARG C 2 261 ? 152.222 146.369 103.786 1.00 36.83  ? 207 ARG B CG  1 
ATOM   7081  C  CD  . ARG C 2 261 ? 151.271 145.222 103.999 1.00 37.12  ? 207 ARG B CD  1 
ATOM   7082  N  NE  . ARG C 2 261 ? 151.966 143.949 103.891 1.00 41.56  ? 207 ARG B NE  1 
ATOM   7083  C  CZ  . ARG C 2 261 ? 152.554 143.334 104.904 1.00 40.47  ? 207 ARG B CZ  1 
ATOM   7084  N  NH1 . ARG C 2 261 ? 152.523 143.833 106.124 1.00 39.86  ? 207 ARG B NH1 1 
ATOM   7085  N  NH2 . ARG C 2 261 ? 153.195 142.192 104.685 1.00 38.72  ? 207 ARG B NH2 1 
ATOM   7086  N  N   . LEU C 2 262 ? 149.915 148.249 102.144 1.00 32.17  ? 208 LEU B N   1 
ATOM   7087  C  CA  . LEU C 2 262 ? 149.220 149.277 102.898 1.00 29.79  ? 208 LEU B CA  1 
ATOM   7088  C  C   . LEU C 2 262 ? 148.877 148.716 104.268 1.00 32.30  ? 208 LEU B C   1 
ATOM   7089  O  O   . LEU C 2 262 ? 148.724 147.507 104.435 1.00 36.57  ? 208 LEU B O   1 
ATOM   7090  C  CB  . LEU C 2 262 ? 147.948 149.734 102.184 1.00 31.52  ? 208 LEU B CB  1 
ATOM   7091  C  CG  . LEU C 2 262 ? 148.094 150.274 100.764 1.00 34.25  ? 208 LEU B CG  1 
ATOM   7092  C  CD1 . LEU C 2 262 ? 146.797 150.871 100.307 1.00 33.85  ? 208 LEU B CD1 1 
ATOM   7093  C  CD2 . LEU C 2 262 ? 149.190 151.302 100.692 1.00 32.72  ? 208 LEU B CD2 1 
ATOM   7094  N  N   . SER C 2 263 ? 148.792 149.589 105.261 1.00 32.49  ? 209 SER B N   1 
ATOM   7095  C  CA  . SER C 2 263 ? 148.558 149.137 106.625 1.00 32.71  ? 209 SER B CA  1 
ATOM   7096  C  C   . SER C 2 263 ? 147.693 150.149 107.351 1.00 34.16  ? 209 SER B C   1 
ATOM   7097  O  O   . SER C 2 263 ? 148.047 151.328 107.427 1.00 35.49  ? 209 SER B O   1 
ATOM   7098  C  CB  . SER C 2 263 ? 149.880 148.925 107.362 1.00 37.41  ? 209 SER B CB  1 
ATOM   7099  O  OG  . SER C 2 263 ? 149.653 148.503 108.690 1.00 49.51  ? 209 SER B OG  1 
ATOM   7100  N  N   . LEU C 2 264 ? 146.567 149.691 107.880 1.00 33.64  ? 210 LEU B N   1 
ATOM   7101  C  CA  . LEU C 2 264 ? 145.652 150.526 108.648 1.00 33.80  ? 210 LEU B CA  1 
ATOM   7102  C  C   . LEU C 2 264 ? 145.642 150.032 110.085 1.00 35.52  ? 210 LEU B C   1 
ATOM   7103  O  O   . LEU C 2 264 ? 145.214 148.908 110.350 1.00 43.33  ? 210 LEU B O   1 
ATOM   7104  C  CB  . LEU C 2 264 ? 144.247 150.483 108.054 1.00 33.23  ? 210 LEU B CB  1 
ATOM   7105  C  CG  . LEU C 2 264 ? 143.091 150.856 108.977 1.00 33.27  ? 210 LEU B CG  1 
ATOM   7106  C  CD1 . LEU C 2 264 ? 143.097 152.328 109.291 1.00 34.52  ? 210 LEU B CD1 1 
ATOM   7107  C  CD2 . LEU C 2 264 ? 141.780 150.445 108.349 1.00 30.25  ? 210 LEU B CD2 1 
ATOM   7108  N  N   . SER C 2 265 ? 146.110 150.862 111.009 1.00 34.50  ? 211 SER B N   1 
ATOM   7109  C  CA  . SER C 2 265 ? 146.240 150.448 112.396 1.00 34.93  ? 211 SER B CA  1 
ATOM   7110  C  C   . SER C 2 265 ? 145.367 151.308 113.296 1.00 36.81  ? 211 SER B C   1 
ATOM   7111  O  O   . SER C 2 265 ? 145.123 152.481 113.012 1.00 41.97  ? 211 SER B O   1 
ATOM   7112  C  CB  . SER C 2 265 ? 147.690 150.519 112.852 1.00 39.07  ? 211 SER B CB  1 
ATOM   7113  O  OG  . SER C 2 265 ? 148.252 151.779 112.554 1.00 46.23  ? 211 SER B OG  1 
ATOM   7114  N  N   . PHE C 2 266 ? 144.894 150.703 114.382 1.00 37.41  ? 212 PHE B N   1 
ATOM   7115  C  CA  . PHE C 2 266 ? 144.091 151.367 115.397 1.00 37.30  ? 212 PHE B CA  1 
ATOM   7116  C  C   . PHE C 2 266 ? 144.746 151.171 116.752 1.00 41.50  ? 212 PHE B C   1 
ATOM   7117  O  O   . PHE C 2 266 ? 145.208 150.071 117.068 1.00 45.21  ? 212 PHE B O   1 
ATOM   7118  C  CB  . PHE C 2 266 ? 142.667 150.809 115.462 1.00 36.10  ? 212 PHE B CB  1 
ATOM   7119  C  CG  . PHE C 2 266 ? 141.921 150.876 114.170 1.00 38.86  ? 212 PHE B CG  1 
ATOM   7120  C  CD1 . PHE C 2 266 ? 141.235 152.015 113.813 1.00 41.79  ? 212 PHE B CD1 1 
ATOM   7121  C  CD2 . PHE C 2 266 ? 141.885 149.788 113.323 1.00 39.27  ? 212 PHE B CD2 1 
ATOM   7122  C  CE1 . PHE C 2 266 ? 140.539 152.074 112.627 1.00 41.83  ? 212 PHE B CE1 1 
ATOM   7123  C  CE2 . PHE C 2 266 ? 141.196 149.844 112.136 1.00 39.15  ? 212 PHE B CE2 1 
ATOM   7124  C  CZ  . PHE C 2 266 ? 140.520 150.988 111.789 1.00 41.95  ? 212 PHE B CZ  1 
ATOM   7125  N  N   . ARG C 2 267 ? 144.768 152.228 117.557 1.00 40.79  ? 213 ARG B N   1 
ATOM   7126  C  CA  . ARG C 2 267 ? 145.227 152.149 118.936 1.00 42.04  ? 213 ARG B CA  1 
ATOM   7127  C  C   . ARG C 2 267 ? 144.021 152.155 119.865 1.00 41.93  ? 213 ARG B C   1 
ATOM   7128  O  O   . ARG C 2 267 ? 143.183 153.055 119.793 1.00 46.46  ? 213 ARG B O   1 
ATOM   7129  C  CB  . ARG C 2 267 ? 146.171 153.304 119.271 1.00 48.40  ? 213 ARG B CB  1 
ATOM   7130  C  CG  . ARG C 2 267 ? 146.775 153.210 120.655 1.00 52.11  ? 213 ARG B CG  1 
ATOM   7131  C  CD  . ARG C 2 267 ? 148.184 153.769 120.708 1.00 57.77  ? 213 ARG B CD  1 
ATOM   7132  N  NE  . ARG C 2 267 ? 148.211 155.172 121.103 1.00 63.35  ? 213 ARG B NE  1 
ATOM   7133  C  CZ  . ARG C 2 267 ? 148.503 156.178 120.291 1.00 68.02  ? 213 ARG B CZ  1 
ATOM   7134  N  NH1 . ARG C 2 267 ? 148.814 155.975 119.022 1.00 67.51  ? 213 ARG B NH1 1 
ATOM   7135  N  NH2 . ARG C 2 267 ? 148.485 157.420 120.764 1.00 67.69  ? 213 ARG B NH2 1 
ATOM   7136  N  N   . LEU C 2 268 ? 143.938 151.150 120.730 1.00 40.88  ? 214 LEU B N   1 
ATOM   7137  C  CA  . LEU C 2 268 ? 142.788 150.911 121.587 1.00 40.01  ? 214 LEU B CA  1 
ATOM   7138  C  C   . LEU C 2 268 ? 143.175 151.054 123.050 1.00 46.79  ? 214 LEU B C   1 
ATOM   7139  O  O   . LEU C 2 268 ? 144.220 150.556 123.473 1.00 52.04  ? 214 LEU B O   1 
ATOM   7140  C  CB  . LEU C 2 268 ? 142.223 149.515 121.357 1.00 38.08  ? 214 LEU B CB  1 
ATOM   7141  C  CG  . LEU C 2 268 ? 141.426 149.282 120.083 1.00 40.02  ? 214 LEU B CG  1 
ATOM   7142  C  CD1 . LEU C 2 268 ? 141.310 147.808 119.813 1.00 38.39  ? 214 LEU B CD1 1 
ATOM   7143  C  CD2 . LEU C 2 268 ? 140.064 149.886 120.246 1.00 43.79  ? 214 LEU B CD2 1 
ATOM   7144  N  N   . LYS C 2 269 ? 142.321 151.715 123.821 1.00 48.85  ? 215 LYS B N   1 
ATOM   7145  C  CA  . LYS C 2 269 ? 142.500 151.873 125.257 1.00 49.63  ? 215 LYS B CA  1 
ATOM   7146  C  C   . LYS C 2 269 ? 141.344 151.189 125.969 1.00 49.56  ? 215 LYS B C   1 
ATOM   7147  O  O   . LYS C 2 269 ? 140.186 151.378 125.591 1.00 52.20  ? 215 LYS B O   1 
ATOM   7148  C  CB  . LYS C 2 269 ? 142.562 153.352 125.640 1.00 47.34  ? 215 LYS B CB  1 
ATOM   7149  C  CG  . LYS C 2 269 ? 142.855 153.608 127.101 1.00 50.05  ? 215 LYS B CG  1 
ATOM   7150  C  CD  . LYS C 2 269 ? 144.232 153.103 127.465 1.00 57.45  ? 215 LYS B CD  1 
ATOM   7151  C  CE  . LYS C 2 269 ? 144.552 153.330 128.934 1.00 62.18  ? 215 LYS B CE  1 
ATOM   7152  N  NZ  . LYS C 2 269 ? 143.739 152.468 129.834 1.00 56.91  ? 215 LYS B NZ  1 
ATOM   7153  N  N   . ARG C 2 270 ? 141.654 150.386 126.983 1.00 48.66  ? 216 ARG B N   1 
ATOM   7154  C  CA  . ARG C 2 270 ? 140.613 149.706 127.739 1.00 48.07  ? 216 ARG B CA  1 
ATOM   7155  C  C   . ARG C 2 270 ? 139.950 150.667 128.717 1.00 54.10  ? 216 ARG B C   1 
ATOM   7156  O  O   . ARG C 2 270 ? 140.613 151.495 129.342 1.00 56.16  ? 216 ARG B O   1 
ATOM   7157  C  CB  . ARG C 2 270 ? 141.183 148.506 128.492 1.00 45.52  ? 216 ARG B CB  1 
ATOM   7158  C  CG  . ARG C 2 270 ? 140.111 147.538 128.952 1.00 45.95  ? 216 ARG B CG  1 
ATOM   7159  C  CD  . ARG C 2 270 ? 140.690 146.319 129.631 1.00 49.06  ? 216 ARG B CD  1 
ATOM   7160  N  NE  . ARG C 2 270 ? 141.543 145.534 128.750 1.00 47.50  ? 216 ARG B NE  1 
ATOM   7161  C  CZ  . ARG C 2 270 ? 141.129 144.502 128.029 1.00 45.35  ? 216 ARG B CZ  1 
ATOM   7162  N  NH1 . ARG C 2 270 ? 139.868 144.109 128.045 1.00 43.78  ? 216 ARG B NH1 1 
ATOM   7163  N  NH2 . ARG C 2 270 ? 142.004 143.846 127.275 1.00 45.34  ? 216 ARG B NH2 1 
ATOM   7164  N  N   . ASN C 2 271 ? 138.630 150.551 128.843 1.00 55.77  ? 217 ASN B N   1 
ATOM   7165  C  CA  . ASN C 2 271 ? 137.850 151.428 129.704 1.00 55.01  ? 217 ASN B CA  1 
ATOM   7166  C  C   . ASN C 2 271 ? 137.864 150.915 131.136 1.00 60.57  ? 217 ASN B C   1 
ATOM   7167  O  O   . ASN C 2 271 ? 137.625 149.730 131.381 1.00 60.59  ? 217 ASN B O   1 
ATOM   7168  C  CB  . ASN C 2 271 ? 136.412 151.537 129.202 1.00 58.20  ? 217 ASN B CB  1 
ATOM   7169  C  CG  . ASN C 2 271 ? 136.298 152.362 127.941 1.00 60.94  ? 217 ASN B CG  1 
ATOM   7170  O  OD1 . ASN C 2 271 ? 137.049 153.314 127.737 1.00 59.71  ? 217 ASN B OD1 1 
ATOM   7171  N  ND2 . ASN C 2 271 ? 135.348 152.006 127.089 1.00 56.61  ? 217 ASN B ND2 1 
ATOM   7172  N  N   . ILE C 2 272 ? 138.124 151.817 132.078 1.00 67.58  ? 218 ILE B N   1 
ATOM   7173  C  CA  . ILE C 2 272 ? 138.226 151.487 133.495 1.00 69.90  ? 218 ILE B CA  1 
ATOM   7174  C  C   . ILE C 2 272 ? 136.938 151.909 134.186 1.00 71.52  ? 218 ILE B C   1 
ATOM   7175  O  O   . ILE C 2 272 ? 136.450 153.027 133.980 1.00 75.83  ? 218 ILE B O   1 
ATOM   7176  C  CB  . ILE C 2 272 ? 139.447 152.168 134.138 1.00 65.97  ? 218 ILE B CB  1 
ATOM   7177  C  CG1 . ILE C 2 272 ? 140.684 151.278 134.021 1.00 62.42  ? 218 ILE B CG1 1 
ATOM   7178  C  CG2 . ILE C 2 272 ? 139.181 152.508 135.590 1.00 66.12  ? 218 ILE B CG2 1 
ATOM   7179  C  CD1 . ILE C 2 272 ? 141.301 151.268 132.653 1.00 62.27  ? 218 ILE B CD1 1 
ATOM   7180  N  N   . GLY C 2 273 ? 136.383 151.016 134.999 1.00 68.20  ? 219 GLY B N   1 
ATOM   7181  C  CA  . GLY C 2 273 ? 135.180 151.321 135.742 1.00 71.30  ? 219 GLY B CA  1 
ATOM   7182  C  C   . GLY C 2 273 ? 135.152 150.671 137.109 1.00 77.49  ? 219 GLY B C   1 
ATOM   7183  O  O   . GLY C 2 273 ? 136.139 150.063 137.540 1.00 80.84  ? 219 GLY B O   1 
ATOM   7184  N  N   . TYR C 2 274 ? 134.016 150.787 137.800 1.00 74.80  ? 220 TYR B N   1 
ATOM   7185  C  CA  . TYR C 2 274 ? 133.899 150.178 139.118 1.00 76.35  ? 220 TYR B CA  1 
ATOM   7186  C  C   . TYR C 2 274 ? 134.082 148.673 139.050 1.00 78.86  ? 220 TYR B C   1 
ATOM   7187  O  O   . TYR C 2 274 ? 134.544 148.060 140.017 1.00 85.63  ? 220 TYR B O   1 
ATOM   7188  C  CB  . TYR C 2 274 ? 132.544 150.512 139.744 1.00 83.74  ? 220 TYR B CB  1 
ATOM   7189  C  CG  . TYR C 2 274 ? 132.298 149.786 141.049 1.00 92.27  ? 220 TYR B CG  1 
ATOM   7190  C  CD1 . TYR C 2 274 ? 132.886 150.223 142.225 1.00 92.73  ? 220 TYR B CD1 1 
ATOM   7191  C  CD2 . TYR C 2 274 ? 131.494 148.657 141.101 1.00 92.69  ? 220 TYR B CD2 1 
ATOM   7192  C  CE1 . TYR C 2 274 ? 132.679 149.561 143.416 1.00 94.24  ? 220 TYR B CE1 1 
ATOM   7193  C  CE2 . TYR C 2 274 ? 131.284 147.988 142.287 1.00 93.22  ? 220 TYR B CE2 1 
ATOM   7194  C  CZ  . TYR C 2 274 ? 131.878 148.447 143.441 1.00 97.51  ? 220 TYR B CZ  1 
ATOM   7195  O  OH  . TYR C 2 274 ? 131.670 147.789 144.630 1.00 107.02 ? 220 TYR B OH  1 
ATOM   7196  N  N   . PHE C 2 275 ? 133.738 148.061 137.923 1.00 76.19  ? 221 PHE B N   1 
ATOM   7197  C  CA  . PHE C 2 275 ? 133.877 146.619 137.804 1.00 78.52  ? 221 PHE B CA  1 
ATOM   7198  C  C   . PHE C 2 275 ? 135.329 146.202 137.632 1.00 74.94  ? 221 PHE B C   1 
ATOM   7199  O  O   . PHE C 2 275 ? 135.705 145.101 138.045 1.00 72.84  ? 221 PHE B O   1 
ATOM   7200  C  CB  . PHE C 2 275 ? 133.009 146.126 136.656 1.00 79.12  ? 221 PHE B CB  1 
ATOM   7201  C  CG  . PHE C 2 275 ? 131.573 146.504 136.810 1.00 83.72  ? 221 PHE B CG  1 
ATOM   7202  C  CD1 . PHE C 2 275 ? 130.739 145.773 137.631 1.00 86.50  ? 221 PHE B CD1 1 
ATOM   7203  C  CD2 . PHE C 2 275 ? 131.065 147.612 136.165 1.00 84.44  ? 221 PHE B CD2 1 
ATOM   7204  C  CE1 . PHE C 2 275 ? 129.423 146.127 137.785 1.00 90.18  ? 221 PHE B CE1 1 
ATOM   7205  C  CE2 . PHE C 2 275 ? 129.749 147.969 136.317 1.00 85.15  ? 221 PHE B CE2 1 
ATOM   7206  C  CZ  . PHE C 2 275 ? 128.926 147.226 137.127 1.00 90.77  ? 221 PHE B CZ  1 
ATOM   7207  N  N   . ILE C 2 276 ? 136.150 147.053 137.022 1.00 75.17  ? 222 ILE B N   1 
ATOM   7208  C  CA  . ILE C 2 276 ? 137.590 146.835 137.059 1.00 73.42  ? 222 ILE B CA  1 
ATOM   7209  C  C   . ILE C 2 276 ? 138.116 147.069 138.468 1.00 71.01  ? 222 ILE B C   1 
ATOM   7210  O  O   . ILE C 2 276 ? 139.014 146.362 138.938 1.00 71.93  ? 222 ILE B O   1 
ATOM   7211  C  CB  . ILE C 2 276 ? 138.296 147.734 136.025 1.00 74.80  ? 222 ILE B CB  1 
ATOM   7212  C  CG1 . ILE C 2 276 ? 138.140 147.166 134.609 1.00 70.35  ? 222 ILE B CG1 1 
ATOM   7213  C  CG2 . ILE C 2 276 ? 139.764 147.910 136.375 1.00 72.23  ? 222 ILE B CG2 1 
ATOM   7214  C  CD1 . ILE C 2 276 ? 136.848 147.549 133.914 1.00 67.95  ? 222 ILE B CD1 1 
ATOM   7215  N  N   . LEU C 2 277 ? 137.554 148.055 139.168 1.00 72.82  ? 223 LEU B N   1 
ATOM   7216  C  CA  . LEU C 2 277 ? 137.998 148.342 140.528 1.00 77.19  ? 223 LEU B CA  1 
ATOM   7217  C  C   . LEU C 2 277 ? 137.702 147.195 141.486 1.00 76.06  ? 223 LEU B C   1 
ATOM   7218  O  O   . LEU C 2 277 ? 138.473 146.961 142.421 1.00 77.72  ? 223 LEU B O   1 
ATOM   7219  C  CB  . LEU C 2 277 ? 137.342 149.626 141.040 1.00 82.03  ? 223 LEU B CB  1 
ATOM   7220  C  CG  . LEU C 2 277 ? 137.622 149.986 142.502 1.00 82.66  ? 223 LEU B CG  1 
ATOM   7221  C  CD1 . LEU C 2 277 ? 139.091 150.325 142.699 1.00 82.91  ? 223 LEU B CD1 1 
ATOM   7222  C  CD2 . LEU C 2 277 ? 136.738 151.126 142.973 1.00 78.38  ? 223 LEU B CD2 1 
ATOM   7223  N  N   . GLN C 2 278 ? 136.613 146.464 141.274 1.00 72.17  ? 224 GLN B N   1 
ATOM   7224  C  CA  . GLN C 2 278 ? 136.176 145.468 142.244 1.00 69.87  ? 224 GLN B CA  1 
ATOM   7225  C  C   . GLN C 2 278 ? 136.969 144.169 142.176 1.00 70.55  ? 224 GLN B C   1 
ATOM   7226  O  O   . GLN C 2 278 ? 136.521 143.162 142.734 1.00 71.96  ? 224 GLN B O   1 
ATOM   7227  C  CB  . GLN C 2 278 ? 134.686 145.174 142.071 1.00 75.47  ? 224 GLN B CB  1 
ATOM   7228  C  CG  . GLN C 2 278 ? 134.337 144.318 140.872 1.00 77.06  ? 224 GLN B CG  1 
ATOM   7229  C  CD  . GLN C 2 278 ? 132.907 143.831 140.923 1.00 82.47  ? 224 GLN B CD  1 
ATOM   7230  O  OE1 . GLN C 2 278 ? 132.229 143.983 141.936 1.00 87.64  ? 224 GLN B OE1 1 
ATOM   7231  N  NE2 . GLN C 2 278 ? 132.437 143.247 139.829 1.00 79.24  ? 224 GLN B NE2 1 
ATOM   7232  N  N   . THR C 2 279 ? 138.126 144.153 141.517 1.00 71.35  ? 225 THR B N   1 
ATOM   7233  C  CA  . THR C 2 279 ? 138.981 142.975 141.527 1.00 67.90  ? 225 THR B CA  1 
ATOM   7234  C  C   . THR C 2 279 ? 140.111 143.067 142.542 1.00 66.49  ? 225 THR B C   1 
ATOM   7235  O  O   . THR C 2 279 ? 140.626 142.029 142.966 1.00 64.73  ? 225 THR B O   1 
ATOM   7236  C  CB  . THR C 2 279 ? 139.576 142.735 140.138 1.00 67.25  ? 225 THR B CB  1 
ATOM   7237  O  OG1 . THR C 2 279 ? 138.655 143.189 139.142 1.00 71.24  ? 225 THR B OG1 1 
ATOM   7238  C  CG2 . THR C 2 279 ? 139.815 141.265 139.928 1.00 66.23  ? 225 THR B CG2 1 
ATOM   7239  N  N   . TYR C 2 280 ? 140.496 144.277 142.946 1.00 64.90  ? 226 TYR B N   1 
ATOM   7240  C  CA  . TYR C 2 280 ? 141.529 144.480 143.952 1.00 67.19  ? 226 TYR B CA  1 
ATOM   7241  C  C   . TYR C 2 280 ? 140.970 144.713 145.348 1.00 70.00  ? 226 TYR B C   1 
ATOM   7242  O  O   . TYR C 2 280 ? 141.673 144.459 146.340 1.00 72.14  ? 226 TYR B O   1 
ATOM   7243  C  CB  . TYR C 2 280 ? 142.400 145.682 143.573 1.00 65.67  ? 226 TYR B CB  1 
ATOM   7244  C  CG  . TYR C 2 280 ? 143.113 145.564 142.246 1.00 67.84  ? 226 TYR B CG  1 
ATOM   7245  C  CD1 . TYR C 2 280 ? 142.504 145.959 141.066 1.00 67.33  ? 226 TYR B CD1 1 
ATOM   7246  C  CD2 . TYR C 2 280 ? 144.409 145.084 142.180 1.00 69.69  ? 226 TYR B CD2 1 
ATOM   7247  C  CE1 . TYR C 2 280 ? 143.163 145.863 139.860 1.00 67.84  ? 226 TYR B CE1 1 
ATOM   7248  C  CE2 . TYR C 2 280 ? 145.074 144.985 140.983 1.00 67.71  ? 226 TYR B CE2 1 
ATOM   7249  C  CZ  . TYR C 2 280 ? 144.450 145.374 139.827 1.00 69.85  ? 226 TYR B CZ  1 
ATOM   7250  O  OH  . TYR C 2 280 ? 145.121 145.269 138.633 1.00 69.82  ? 226 TYR B OH  1 
ATOM   7251  N  N   . MET C 2 281 ? 139.736 145.203 145.440 1.00 67.09  ? 227 MET B N   1 
ATOM   7252  C  CA  . MET C 2 281 ? 139.180 145.596 146.731 1.00 67.29  ? 227 MET B CA  1 
ATOM   7253  C  C   . MET C 2 281 ? 139.084 144.440 147.717 1.00 65.42  ? 227 MET B C   1 
ATOM   7254  O  O   . MET C 2 281 ? 139.438 144.638 148.893 1.00 65.67  ? 227 MET B O   1 
ATOM   7255  C  CB  . MET C 2 281 ? 137.823 146.275 146.518 1.00 65.52  ? 227 MET B CB  1 
ATOM   7256  C  CG  . MET C 2 281 ? 137.530 147.374 147.522 1.00 71.12  ? 227 MET B CG  1 
ATOM   7257  S  SD  . MET C 2 281 ? 138.810 148.643 147.531 1.00 94.90  ? 227 MET B SD  1 
ATOM   7258  C  CE  . MET C 2 281 ? 138.177 149.758 148.778 1.00 92.55  ? 227 MET B CE  1 
ATOM   7259  N  N   . PRO C 2 282 ? 138.600 143.246 147.346 1.00 60.49  ? 228 PRO B N   1 
ATOM   7260  C  CA  . PRO C 2 282 ? 138.587 142.149 148.329 1.00 59.88  ? 228 PRO B CA  1 
ATOM   7261  C  C   . PRO C 2 282 ? 139.958 141.822 148.893 1.00 57.97  ? 228 PRO B C   1 
ATOM   7262  O  O   . PRO C 2 282 ? 140.091 141.606 150.105 1.00 58.31  ? 228 PRO B O   1 
ATOM   7263  C  CB  . PRO C 2 282 ? 138.013 140.974 147.529 1.00 52.95  ? 228 PRO B CB  1 
ATOM   7264  C  CG  . PRO C 2 282 ? 137.209 141.597 146.477 1.00 54.95  ? 228 PRO B CG  1 
ATOM   7265  C  CD  . PRO C 2 282 ? 137.904 142.865 146.106 1.00 56.87  ? 228 PRO B CD  1 
ATOM   7266  N  N   . SER C 2 283 ? 140.987 141.797 148.047 1.00 57.36  ? 229 SER B N   1 
ATOM   7267  C  CA  . SER C 2 283 ? 142.329 141.497 148.527 1.00 55.37  ? 229 SER B CA  1 
ATOM   7268  C  C   . SER C 2 283 ? 142.826 142.573 149.480 1.00 58.18  ? 229 SER B C   1 
ATOM   7269  O  O   . SER C 2 283 ? 143.424 142.262 150.519 1.00 61.75  ? 229 SER B O   1 
ATOM   7270  C  CB  . SER C 2 283 ? 143.282 141.346 147.347 1.00 59.61  ? 229 SER B CB  1 
ATOM   7271  O  OG  . SER C 2 283 ? 142.878 140.280 146.508 1.00 60.70  ? 229 SER B OG  1 
ATOM   7272  N  N   . ILE C 2 284 ? 142.587 143.843 149.151 1.00 57.90  ? 230 ILE B N   1 
ATOM   7273  C  CA  . ILE C 2 284 ? 143.016 144.914 150.046 1.00 59.84  ? 230 ILE B CA  1 
ATOM   7274  C  C   . ILE C 2 284 ? 142.306 144.805 151.391 1.00 60.98  ? 230 ILE B C   1 
ATOM   7275  O  O   . ILE C 2 284 ? 142.923 144.962 152.457 1.00 60.19  ? 230 ILE B O   1 
ATOM   7276  C  CB  . ILE C 2 284 ? 142.783 146.282 149.385 1.00 61.69  ? 230 ILE B CB  1 
ATOM   7277  C  CG1 . ILE C 2 284 ? 143.647 146.398 148.131 1.00 65.36  ? 230 ILE B CG1 1 
ATOM   7278  C  CG2 . ILE C 2 284 ? 143.097 147.401 150.352 1.00 63.85  ? 230 ILE B CG2 1 
ATOM   7279  C  CD1 . ILE C 2 284 ? 143.570 147.733 147.459 1.00 67.39  ? 230 ILE B CD1 1 
ATOM   7280  N  N   . LEU C 2 285 ? 141.002 144.521 151.366 1.00 60.12  ? 231 LEU B N   1 
ATOM   7281  C  CA  . LEU C 2 285 ? 140.245 144.428 152.609 1.00 56.46  ? 231 LEU B CA  1 
ATOM   7282  C  C   . LEU C 2 285 ? 140.727 143.267 153.469 1.00 57.88  ? 231 LEU B C   1 
ATOM   7283  O  O   . LEU C 2 285 ? 140.846 143.401 154.693 1.00 60.09  ? 231 LEU B O   1 
ATOM   7284  C  CB  . LEU C 2 285 ? 138.757 144.298 152.302 1.00 55.79  ? 231 LEU B CB  1 
ATOM   7285  C  CG  . LEU C 2 285 ? 138.160 145.527 151.620 1.00 57.49  ? 231 LEU B CG  1 
ATOM   7286  C  CD1 . LEU C 2 285 ? 136.704 145.307 151.294 1.00 59.88  ? 231 LEU B CD1 1 
ATOM   7287  C  CD2 . LEU C 2 285 ? 138.332 146.753 152.490 1.00 55.71  ? 231 LEU B CD2 1 
ATOM   7288  N  N   . ILE C 2 286 ? 141.017 142.122 152.850 1.00 56.57  ? 232 ILE B N   1 
ATOM   7289  C  CA  . ILE C 2 286 ? 141.514 140.983 153.615 1.00 55.12  ? 232 ILE B CA  1 
ATOM   7290  C  C   . ILE C 2 286 ? 142.892 141.281 154.189 1.00 56.07  ? 232 ILE B C   1 
ATOM   7291  O  O   . ILE C 2 286 ? 143.215 140.865 155.307 1.00 59.76  ? 232 ILE B O   1 
ATOM   7292  C  CB  . ILE C 2 286 ? 141.524 139.715 152.748 1.00 54.19  ? 232 ILE B CB  1 
ATOM   7293  C  CG1 . ILE C 2 286 ? 140.110 139.371 152.300 1.00 50.20  ? 232 ILE B CG1 1 
ATOM   7294  C  CG2 . ILE C 2 286 ? 142.101 138.553 153.523 1.00 53.49  ? 232 ILE B CG2 1 
ATOM   7295  C  CD1 . ILE C 2 286 ? 139.203 138.976 153.426 1.00 55.34  ? 232 ILE B CD1 1 
ATOM   7296  N  N   . THR C 2 287 ? 143.730 142.002 153.444 1.00 53.50  ? 233 THR B N   1 
ATOM   7297  C  CA  . THR C 2 287 ? 145.037 142.370 153.980 1.00 54.26  ? 233 THR B CA  1 
ATOM   7298  C  C   . THR C 2 287 ? 144.900 143.255 155.214 1.00 59.49  ? 233 THR B C   1 
ATOM   7299  O  O   . THR C 2 287 ? 145.609 143.068 156.212 1.00 62.23  ? 233 THR B O   1 
ATOM   7300  C  CB  . THR C 2 287 ? 145.861 143.069 152.905 1.00 57.13  ? 233 THR B CB  1 
ATOM   7301  O  OG1 . THR C 2 287 ? 145.873 142.265 151.724 1.00 60.10  ? 233 THR B OG1 1 
ATOM   7302  C  CG2 . THR C 2 287 ? 147.279 143.257 153.375 1.00 57.23  ? 233 THR B CG2 1 
ATOM   7303  N  N   . ILE C 2 288 ? 143.980 144.218 155.174 1.00 61.04  ? 234 ILE B N   1 
ATOM   7304  C  CA  . ILE C 2 288 ? 143.790 145.078 156.338 1.00 61.03  ? 234 ILE B CA  1 
ATOM   7305  C  C   . ILE C 2 288 ? 143.232 144.280 157.516 1.00 58.67  ? 234 ILE B C   1 
ATOM   7306  O  O   . ILE C 2 288 ? 143.639 144.476 158.673 1.00 60.39  ? 234 ILE B O   1 
ATOM   7307  C  CB  . ILE C 2 288 ? 142.900 146.272 155.964 1.00 62.84  ? 234 ILE B CB  1 
ATOM   7308  C  CG1 . ILE C 2 288 ? 143.611 147.119 154.906 1.00 58.77  ? 234 ILE B CG1 1 
ATOM   7309  C  CG2 . ILE C 2 288 ? 142.580 147.101 157.189 1.00 64.89  ? 234 ILE B CG2 1 
ATOM   7310  C  CD1 . ILE C 2 288 ? 142.784 148.244 154.353 1.00 59.50  ? 234 ILE B CD1 1 
ATOM   7311  N  N   . LEU C 2 289 ? 142.307 143.357 157.244 1.00 58.64  ? 235 LEU B N   1 
ATOM   7312  C  CA  . LEU C 2 289 ? 141.835 142.459 158.292 1.00 59.39  ? 235 LEU B CA  1 
ATOM   7313  C  C   . LEU C 2 289 ? 142.989 141.687 158.918 1.00 63.40  ? 235 LEU B C   1 
ATOM   7314  O  O   . LEU C 2 289 ? 143.034 141.502 160.138 1.00 65.43  ? 235 LEU B O   1 
ATOM   7315  C  CB  . LEU C 2 289 ? 140.802 141.487 157.730 1.00 58.60  ? 235 LEU B CB  1 
ATOM   7316  C  CG  . LEU C 2 289 ? 139.339 141.911 157.737 1.00 57.90  ? 235 LEU B CG  1 
ATOM   7317  C  CD1 . LEU C 2 289 ? 138.500 140.824 157.104 1.00 58.13  ? 235 LEU B CD1 1 
ATOM   7318  C  CD2 . LEU C 2 289 ? 138.879 142.183 159.151 1.00 61.63  ? 235 LEU B CD2 1 
ATOM   7319  N  N   . SER C 2 290 ? 143.928 141.222 158.095 1.00 63.74  ? 236 SER B N   1 
ATOM   7320  C  CA  . SER C 2 290 ? 145.086 140.517 158.629 1.00 62.68  ? 236 SER B CA  1 
ATOM   7321  C  C   . SER C 2 290 ? 145.918 141.431 159.517 1.00 65.84  ? 236 SER B C   1 
ATOM   7322  O  O   . SER C 2 290 ? 146.464 140.990 160.534 1.00 69.27  ? 236 SER B O   1 
ATOM   7323  C  CB  . SER C 2 290 ? 145.936 139.958 157.491 1.00 60.61  ? 236 SER B CB  1 
ATOM   7324  O  OG  . SER C 2 290 ? 146.498 141.002 156.723 1.00 63.69  ? 236 SER B OG  1 
ATOM   7325  N  N   . TRP C 2 291 ? 146.041 142.705 159.139 1.00 67.83  ? 237 TRP B N   1 
ATOM   7326  C  CA  . TRP C 2 291 ? 146.749 143.651 160.002 1.00 67.86  ? 237 TRP B CA  1 
ATOM   7327  C  C   . TRP C 2 291 ? 146.087 143.749 161.367 1.00 70.17  ? 237 TRP B C   1 
ATOM   7328  O  O   . TRP C 2 291 ? 146.772 143.834 162.391 1.00 72.28  ? 237 TRP B O   1 
ATOM   7329  C  CB  . TRP C 2 291 ? 146.786 145.042 159.387 1.00 64.64  ? 237 TRP B CB  1 
ATOM   7330  C  CG  . TRP C 2 291 ? 147.494 145.166 158.120 1.00 63.37  ? 237 TRP B CG  1 
ATOM   7331  C  CD1 . TRP C 2 291 ? 148.389 144.300 157.582 1.00 64.65  ? 237 TRP B CD1 1 
ATOM   7332  C  CD2 . TRP C 2 291 ? 147.363 146.242 157.200 1.00 65.46  ? 237 TRP B CD2 1 
ATOM   7333  N  NE1 . TRP C 2 291 ? 148.830 144.775 156.373 1.00 68.54  ? 237 TRP B NE1 1 
ATOM   7334  C  CE2 . TRP C 2 291 ? 148.210 145.968 156.117 1.00 68.02  ? 237 TRP B CE2 1 
ATOM   7335  C  CE3 . TRP C 2 291 ? 146.603 147.414 157.185 1.00 66.86  ? 237 TRP B CE3 1 
ATOM   7336  C  CZ2 . TRP C 2 291 ? 148.321 146.821 155.034 1.00 68.76  ? 237 TRP B CZ2 1 
ATOM   7337  C  CZ3 . TRP C 2 291 ? 146.717 148.260 156.111 1.00 69.51  ? 237 TRP B CZ3 1 
ATOM   7338  C  CH2 . TRP C 2 291 ? 147.570 147.962 155.048 1.00 71.54  ? 237 TRP B CH2 1 
ATOM   7339  N  N   . VAL C 2 292 ? 144.751 143.764 161.390 1.00 68.91  ? 238 VAL B N   1 
ATOM   7340  C  CA  . VAL C 2 292 ? 144.008 144.029 162.626 1.00 68.82  ? 238 VAL B CA  1 
ATOM   7341  C  C   . VAL C 2 292 ? 144.480 143.160 163.788 1.00 71.20  ? 238 VAL B C   1 
ATOM   7342  O  O   . VAL C 2 292 ? 144.441 143.589 164.948 1.00 72.06  ? 238 VAL B O   1 
ATOM   7343  C  CB  . VAL C 2 292 ? 142.494 143.859 162.373 1.00 67.91  ? 238 VAL B CB  1 
ATOM   7344  C  CG1 . VAL C 2 292 ? 141.726 143.805 163.676 1.00 65.08  ? 238 VAL B CG1 1 
ATOM   7345  C  CG2 . VAL C 2 292 ? 141.975 145.001 161.519 1.00 68.06  ? 238 VAL B CG2 1 
ATOM   7346  N  N   . SER C 2 293 ? 144.976 141.953 163.503 1.00 73.82  ? 239 SER B N   1 
ATOM   7347  C  CA  . SER C 2 293 ? 145.367 141.026 164.563 1.00 75.47  ? 239 SER B CA  1 
ATOM   7348  C  C   . SER C 2 293 ? 146.457 141.578 165.470 1.00 79.41  ? 239 SER B C   1 
ATOM   7349  O  O   . SER C 2 293 ? 146.598 141.104 166.601 1.00 86.29  ? 239 SER B O   1 
ATOM   7350  C  CB  . SER C 2 293 ? 145.851 139.706 163.965 1.00 76.43  ? 239 SER B CB  1 
ATOM   7351  O  OG  . SER C 2 293 ? 144.825 139.069 163.232 1.00 83.42  ? 239 SER B OG  1 
ATOM   7352  N  N   . PHE C 2 294 ? 147.234 142.558 165.007 1.00 79.56  ? 240 PHE B N   1 
ATOM   7353  C  CA  . PHE C 2 294 ? 148.362 143.045 165.793 1.00 79.39  ? 240 PHE B CA  1 
ATOM   7354  C  C   . PHE C 2 294 ? 147.928 143.794 167.044 1.00 83.76  ? 240 PHE B C   1 
ATOM   7355  O  O   . PHE C 2 294 ? 148.752 144.009 167.937 1.00 84.75  ? 240 PHE B O   1 
ATOM   7356  C  CB  . PHE C 2 294 ? 149.243 143.955 164.940 1.00 77.00  ? 240 PHE B CB  1 
ATOM   7357  C  CG  . PHE C 2 294 ? 149.738 143.313 163.680 1.00 77.09  ? 240 PHE B CG  1 
ATOM   7358  C  CD1 . PHE C 2 294 ? 150.080 141.978 163.656 1.00 77.58  ? 240 PHE B CD1 1 
ATOM   7359  C  CD2 . PHE C 2 294 ? 149.856 144.047 162.517 1.00 75.70  ? 240 PHE B CD2 1 
ATOM   7360  C  CE1 . PHE C 2 294 ? 150.533 141.388 162.498 1.00 74.46  ? 240 PHE B CE1 1 
ATOM   7361  C  CE2 . PHE C 2 294 ? 150.305 143.460 161.358 1.00 72.59  ? 240 PHE B CE2 1 
ATOM   7362  C  CZ  . PHE C 2 294 ? 150.647 142.130 161.350 1.00 71.15  ? 240 PHE B CZ  1 
ATOM   7363  N  N   . TRP C 2 295 ? 146.661 144.188 167.133 1.00 85.16  ? 241 TRP B N   1 
ATOM   7364  C  CA  . TRP C 2 295 ? 146.165 145.009 168.226 1.00 85.01  ? 241 TRP B CA  1 
ATOM   7365  C  C   . TRP C 2 295 ? 145.465 144.195 169.304 1.00 87.97  ? 241 TRP B C   1 
ATOM   7366  O  O   . TRP C 2 295 ? 144.839 144.776 170.194 1.00 92.21  ? 241 TRP B O   1 
ATOM   7367  C  CB  . TRP C 2 295 ? 145.221 146.078 167.679 1.00 81.76  ? 241 TRP B CB  1 
ATOM   7368  C  CG  . TRP C 2 295 ? 145.851 146.912 166.618 1.00 84.85  ? 241 TRP B CG  1 
ATOM   7369  C  CD1 . TRP C 2 295 ? 145.961 146.609 165.293 1.00 85.15  ? 241 TRP B CD1 1 
ATOM   7370  C  CD2 . TRP C 2 295 ? 146.470 148.187 166.789 1.00 86.59  ? 241 TRP B CD2 1 
ATOM   7371  N  NE1 . TRP C 2 295 ? 146.610 147.618 164.628 1.00 83.03  ? 241 TRP B NE1 1 
ATOM   7372  C  CE2 . TRP C 2 295 ? 146.934 148.600 165.526 1.00 87.57  ? 241 TRP B CE2 1 
ATOM   7373  C  CE3 . TRP C 2 295 ? 146.677 149.022 167.888 1.00 85.62  ? 241 TRP B CE3 1 
ATOM   7374  C  CZ2 . TRP C 2 295 ? 147.588 149.809 165.332 1.00 87.05  ? 241 TRP B CZ2 1 
ATOM   7375  C  CZ3 . TRP C 2 295 ? 147.328 150.221 167.694 1.00 87.65  ? 241 TRP B CZ3 1 
ATOM   7376  C  CH2 . TRP C 2 295 ? 147.776 150.605 166.427 1.00 90.14  ? 241 TRP B CH2 1 
ATOM   7377  N  N   . ILE C 2 296 ? 145.560 142.872 169.250 1.00 86.92  ? 242 ILE B N   1 
ATOM   7378  C  CA  . ILE C 2 296 ? 144.902 141.990 170.205 1.00 91.01  ? 242 ILE B CA  1 
ATOM   7379  C  C   . ILE C 2 296 ? 145.943 141.468 171.183 1.00 95.68  ? 242 ILE B C   1 
ATOM   7380  O  O   . ILE C 2 296 ? 147.026 141.034 170.774 1.00 95.10  ? 242 ILE B O   1 
ATOM   7381  C  CB  . ILE C 2 296 ? 144.189 140.831 169.490 1.00 89.05  ? 242 ILE B CB  1 
ATOM   7382  C  CG1 . ILE C 2 296 ? 143.143 141.368 168.516 1.00 82.00  ? 242 ILE B CG1 1 
ATOM   7383  C  CG2 . ILE C 2 296 ? 143.541 139.902 170.499 1.00 94.48  ? 242 ILE B CG2 1 
ATOM   7384  C  CD1 . ILE C 2 296 ? 142.479 140.296 167.692 1.00 81.31  ? 242 ILE B CD1 1 
ATOM   7385  N  N   . ASN C 2 297 ? 145.619 141.514 172.473 1.00 100.32 ? 243 ASN B N   1 
ATOM   7386  C  CA  . ASN C 2 297 ? 146.531 141.014 173.491 1.00 105.83 ? 243 ASN B CA  1 
ATOM   7387  C  C   . ASN C 2 297 ? 146.726 139.509 173.346 1.00 109.07 ? 243 ASN B C   1 
ATOM   7388  O  O   . ASN C 2 297 ? 145.846 138.786 172.874 1.00 107.98 ? 243 ASN B O   1 
ATOM   7389  C  CB  . ASN C 2 297 ? 146.005 141.343 174.886 1.00 106.24 ? 243 ASN B CB  1 
ATOM   7390  C  CG  . ASN C 2 297 ? 146.148 142.811 175.231 1.00 110.18 ? 243 ASN B CG  1 
ATOM   7391  O  OD1 . ASN C 2 297 ? 147.135 143.223 175.838 1.00 112.60 ? 243 ASN B OD1 1 
ATOM   7392  N  ND2 . ASN C 2 297 ? 145.160 143.611 174.845 1.00 105.68 ? 243 ASN B ND2 1 
ATOM   7393  N  N   . TYR C 2 298 ? 147.906 139.041 173.758 1.00 112.21 ? 244 TYR B N   1 
ATOM   7394  C  CA  . TYR C 2 298 ? 148.246 137.633 173.587 1.00 113.61 ? 244 TYR B CA  1 
ATOM   7395  C  C   . TYR C 2 298 ? 147.328 136.725 174.391 1.00 114.87 ? 244 TYR B C   1 
ATOM   7396  O  O   . TYR C 2 298 ? 147.124 135.564 174.017 1.00 114.08 ? 244 TYR B O   1 
ATOM   7397  C  CB  . TYR C 2 298 ? 149.702 137.398 173.984 1.00 111.97 ? 244 TYR B CB  1 
ATOM   7398  C  CG  . TYR C 2 298 ? 150.129 135.952 173.925 1.00 113.04 ? 244 TYR B CG  1 
ATOM   7399  C  CD1 . TYR C 2 298 ? 150.640 135.409 172.756 1.00 111.50 ? 244 TYR B CD1 1 
ATOM   7400  C  CD2 . TYR C 2 298 ? 150.030 135.132 175.039 1.00 110.96 ? 244 TYR B CD2 1 
ATOM   7401  C  CE1 . TYR C 2 298 ? 151.034 134.088 172.700 1.00 112.11 ? 244 TYR B CE1 1 
ATOM   7402  C  CE2 . TYR C 2 298 ? 150.417 133.815 174.990 1.00 112.80 ? 244 TYR B CE2 1 
ATOM   7403  C  CZ  . TYR C 2 298 ? 150.922 133.297 173.822 1.00 113.94 ? 244 TYR B CZ  1 
ATOM   7404  O  OH  . TYR C 2 298 ? 151.313 131.979 173.777 1.00 111.75 ? 244 TYR B OH  1 
ATOM   7405  N  N   . ASP C 2 299 ? 146.773 137.224 175.496 1.00 114.15 ? 245 ASP B N   1 
ATOM   7406  C  CA  . ASP C 2 299 ? 145.876 136.404 176.300 1.00 114.81 ? 245 ASP B CA  1 
ATOM   7407  C  C   . ASP C 2 299 ? 144.662 135.971 175.490 1.00 116.22 ? 245 ASP B C   1 
ATOM   7408  O  O   . ASP C 2 299 ? 144.182 134.841 175.632 1.00 116.80 ? 245 ASP B O   1 
ATOM   7409  C  CB  . ASP C 2 299 ? 145.447 137.173 177.548 1.00 115.58 ? 245 ASP B CB  1 
ATOM   7410  C  CG  . ASP C 2 299 ? 144.768 136.290 178.571 1.00 119.36 ? 245 ASP B CG  1 
ATOM   7411  O  OD1 . ASP C 2 299 ? 144.868 135.052 178.449 1.00 119.20 ? 245 ASP B OD1 1 
ATOM   7412  O  OD2 . ASP C 2 299 ? 144.131 136.834 179.498 1.00 119.91 ? 245 ASP B OD2 1 
ATOM   7413  N  N   . ALA C 2 300 ? 144.158 136.852 174.629 1.00 115.18 ? 246 ALA B N   1 
ATOM   7414  C  CA  . ALA C 2 300 ? 143.054 136.517 173.734 1.00 109.84 ? 246 ALA B CA  1 
ATOM   7415  C  C   . ALA C 2 300 ? 143.610 136.076 172.382 1.00 107.11 ? 246 ALA B C   1 
ATOM   7416  O  O   . ALA C 2 300 ? 143.446 136.733 171.356 1.00 106.38 ? 246 ALA B O   1 
ATOM   7417  C  CB  . ALA C 2 300 ? 142.108 137.705 173.594 1.00 106.00 ? 246 ALA B CB  1 
ATOM   7418  N  N   . SER C 2 301 ? 144.289 134.928 172.402 1.00 107.80 ? 247 SER B N   1 
ATOM   7419  C  CA  . SER C 2 301 ? 144.860 134.380 171.179 1.00 106.28 ? 247 SER B CA  1 
ATOM   7420  C  C   . SER C 2 301 ? 143.814 133.720 170.294 1.00 102.73 ? 247 SER B C   1 
ATOM   7421  O  O   . SER C 2 301 ? 144.085 133.478 169.111 1.00 98.50  ? 247 SER B O   1 
ATOM   7422  C  CB  . SER C 2 301 ? 145.958 133.370 171.512 1.00 105.00 ? 247 SER B CB  1 
ATOM   7423  O  OG  . SER C 2 301 ? 145.418 132.225 172.144 1.00 106.42 ? 247 SER B OG  1 
ATOM   7424  N  N   . ALA C 2 302 ? 142.633 133.422 170.840 1.00 101.27 ? 248 ALA B N   1 
ATOM   7425  C  CA  . ALA C 2 302 ? 141.573 132.839 170.028 1.00 98.90  ? 248 ALA B CA  1 
ATOM   7426  C  C   . ALA C 2 302 ? 141.169 133.779 168.902 1.00 96.57  ? 248 ALA B C   1 
ATOM   7427  O  O   . ALA C 2 302 ? 141.006 133.352 167.752 1.00 93.70  ? 248 ALA B O   1 
ATOM   7428  C  CB  . ALA C 2 302 ? 140.367 132.502 170.904 1.00 97.34  ? 248 ALA B CB  1 
ATOM   7429  N  N   . ALA C 2 303 ? 141.019 135.068 169.208 1.00 93.49  ? 249 ALA B N   1 
ATOM   7430  C  CA  . ALA C 2 303 ? 140.680 136.031 168.169 1.00 88.56  ? 249 ALA B CA  1 
ATOM   7431  C  C   . ALA C 2 303 ? 141.782 136.118 167.125 1.00 89.90  ? 249 ALA B C   1 
ATOM   7432  O  O   . ALA C 2 303 ? 141.504 136.202 165.923 1.00 88.46  ? 249 ALA B O   1 
ATOM   7433  C  CB  . ALA C 2 303 ? 140.411 137.402 168.785 1.00 82.20  ? 249 ALA B CB  1 
ATOM   7434  N  N   . ARG C 2 304 ? 143.040 136.090 167.562 1.00 89.53  ? 250 ARG B N   1 
ATOM   7435  C  CA  . ARG C 2 304 ? 144.147 136.205 166.621 1.00 89.00  ? 250 ARG B CA  1 
ATOM   7436  C  C   . ARG C 2 304 ? 144.179 135.022 165.662 1.00 86.86  ? 250 ARG B C   1 
ATOM   7437  O  O   . ARG C 2 304 ? 144.331 135.196 164.446 1.00 85.80  ? 250 ARG B O   1 
ATOM   7438  C  CB  . ARG C 2 304 ? 145.465 136.325 167.382 1.00 88.23  ? 250 ARG B CB  1 
ATOM   7439  C  CG  . ARG C 2 304 ? 145.451 137.400 168.449 1.00 92.49  ? 250 ARG B CG  1 
ATOM   7440  C  CD  . ARG C 2 304 ? 146.853 137.738 168.913 1.00 96.57  ? 250 ARG B CD  1 
ATOM   7441  N  NE  . ARG C 2 304 ? 147.659 138.305 167.840 1.00 96.04  ? 250 ARG B NE  1 
ATOM   7442  C  CZ  . ARG C 2 304 ? 148.866 138.825 168.007 1.00 95.52  ? 250 ARG B CZ  1 
ATOM   7443  N  NH1 . ARG C 2 304 ? 149.438 138.875 169.198 1.00 92.44  ? 250 ARG B NH1 1 
ATOM   7444  N  NH2 . ARG C 2 304 ? 149.517 139.304 166.951 1.00 90.21  ? 250 ARG B NH2 1 
ATOM   7445  N  N   . VAL C 2 305 ? 144.020 133.805 166.187 1.00 85.39  ? 251 VAL B N   1 
ATOM   7446  C  CA  . VAL C 2 305 ? 144.062 132.637 165.314 1.00 82.53  ? 251 VAL B CA  1 
ATOM   7447  C  C   . VAL C 2 305 ? 142.839 132.597 164.406 1.00 79.38  ? 251 VAL B C   1 
ATOM   7448  O  O   . VAL C 2 305 ? 142.933 132.194 163.239 1.00 77.42  ? 251 VAL B O   1 
ATOM   7449  C  CB  . VAL C 2 305 ? 144.217 131.343 166.133 1.00 86.23  ? 251 VAL B CB  1 
ATOM   7450  C  CG1 . VAL C 2 305 ? 145.534 131.360 166.889 1.00 88.39  ? 251 VAL B CG1 1 
ATOM   7451  C  CG2 . VAL C 2 305 ? 143.053 131.150 167.081 1.00 86.14  ? 251 VAL B CG2 1 
ATOM   7452  N  N   . ALA C 2 306 ? 141.675 133.013 164.916 1.00 78.71  ? 252 ALA B N   1 
ATOM   7453  C  CA  . ALA C 2 306 ? 140.487 133.064 164.072 1.00 76.32  ? 252 ALA B CA  1 
ATOM   7454  C  C   . ALA C 2 306 ? 140.683 134.032 162.915 1.00 74.77  ? 252 ALA B C   1 
ATOM   7455  O  O   . ALA C 2 306 ? 140.332 133.723 161.769 1.00 74.36  ? 252 ALA B O   1 
ATOM   7456  C  CB  . ALA C 2 306 ? 139.269 133.459 164.902 1.00 73.86  ? 252 ALA B CB  1 
ATOM   7457  N  N   . LEU C 2 307 ? 141.258 135.203 163.192 1.00 72.33  ? 253 LEU B N   1 
ATOM   7458  C  CA  . LEU C 2 307 ? 141.543 136.151 162.124 1.00 67.68  ? 253 LEU B CA  1 
ATOM   7459  C  C   . LEU C 2 307 ? 142.526 135.568 161.121 1.00 68.80  ? 253 LEU B C   1 
ATOM   7460  O  O   . LEU C 2 307 ? 142.338 135.706 159.906 1.00 68.52  ? 253 LEU B O   1 
ATOM   7461  C  CB  . LEU C 2 307 ? 142.085 137.452 162.708 1.00 68.60  ? 253 LEU B CB  1 
ATOM   7462  C  CG  . LEU C 2 307 ? 141.040 138.385 163.310 1.00 70.98  ? 253 LEU B CG  1 
ATOM   7463  C  CD1 . LEU C 2 307 ? 141.704 139.507 164.071 1.00 71.53  ? 253 LEU B CD1 1 
ATOM   7464  C  CD2 . LEU C 2 307 ? 140.153 138.941 162.215 1.00 69.11  ? 253 LEU B CD2 1 
ATOM   7465  N  N   . GLY C 2 308 ? 143.575 134.905 161.607 1.00 67.72  ? 254 GLY B N   1 
ATOM   7466  C  CA  . GLY C 2 308 ? 144.553 134.338 160.693 1.00 64.87  ? 254 GLY B CA  1 
ATOM   7467  C  C   . GLY C 2 308 ? 143.944 133.320 159.748 1.00 64.61  ? 254 GLY B C   1 
ATOM   7468  O  O   . GLY C 2 308 ? 144.139 133.387 158.528 1.00 63.81  ? 254 GLY B O   1 
ATOM   7469  N  N   . ILE C 2 309 ? 143.173 132.378 160.294 1.00 63.87  ? 255 ILE B N   1 
ATOM   7470  C  CA  . ILE C 2 309 ? 142.598 131.335 159.451 1.00 61.10  ? 255 ILE B CA  1 
ATOM   7471  C  C   . ILE C 2 309 ? 141.570 131.923 158.492 1.00 59.58  ? 255 ILE B C   1 
ATOM   7472  O  O   . ILE C 2 309 ? 141.534 131.562 157.307 1.00 61.12  ? 255 ILE B O   1 
ATOM   7473  C  CB  . ILE C 2 309 ? 142.007 130.198 160.305 1.00 61.40  ? 255 ILE B CB  1 
ATOM   7474  C  CG1 . ILE C 2 309 ? 141.363 129.142 159.410 1.00 57.66  ? 255 ILE B CG1 1 
ATOM   7475  C  CG2 . ILE C 2 309 ? 140.989 130.713 161.290 1.00 61.00  ? 255 ILE B CG2 1 
ATOM   7476  C  CD1 . ILE C 2 309 ? 140.971 127.901 160.148 1.00 57.62  ? 255 ILE B CD1 1 
ATOM   7477  N  N   . THR C 2 310 ? 140.731 132.847 158.972 1.00 58.81  ? 256 THR B N   1 
ATOM   7478  C  CA  . THR C 2 310 ? 139.742 133.461 158.095 1.00 58.12  ? 256 THR B CA  1 
ATOM   7479  C  C   . THR C 2 310 ? 140.415 134.168 156.929 1.00 59.55  ? 256 THR B C   1 
ATOM   7480  O  O   . THR C 2 310 ? 140.024 133.986 155.770 1.00 59.44  ? 256 THR B O   1 
ATOM   7481  C  CB  . THR C 2 310 ? 138.873 134.442 158.880 1.00 60.64  ? 256 THR B CB  1 
ATOM   7482  O  OG1 . THR C 2 310 ? 138.132 133.737 159.879 1.00 67.18  ? 256 THR B OG1 1 
ATOM   7483  C  CG2 . THR C 2 310 ? 137.912 135.157 157.954 1.00 57.03  ? 256 THR B CG2 1 
ATOM   7484  N  N   . THR C 2 311 ? 141.448 134.967 157.212 1.00 60.13  ? 257 THR B N   1 
ATOM   7485  C  CA  . THR C 2 311 ? 142.104 135.710 156.145 1.00 55.68  ? 257 THR B CA  1 
ATOM   7486  C  C   . THR C 2 311 ? 142.774 134.779 155.147 1.00 57.03  ? 257 THR B C   1 
ATOM   7487  O  O   . THR C 2 311 ? 142.657 134.982 153.936 1.00 58.76  ? 257 THR B O   1 
ATOM   7488  C  CB  . THR C 2 311 ? 143.123 136.690 156.717 1.00 56.81  ? 257 THR B CB  1 
ATOM   7489  O  OG1 . THR C 2 311 ? 144.022 135.994 157.584 1.00 61.32  ? 257 THR B OG1 1 
ATOM   7490  C  CG2 . THR C 2 311 ? 142.427 137.786 157.485 1.00 56.77  ? 257 THR B CG2 1 
ATOM   7491  N  N   . VAL C 2 312 ? 143.480 133.753 155.627 1.00 55.00  ? 258 VAL B N   1 
ATOM   7492  C  CA  . VAL C 2 312 ? 144.199 132.880 154.702 1.00 53.04  ? 258 VAL B CA  1 
ATOM   7493  C  C   . VAL C 2 312 ? 143.226 132.123 153.805 1.00 52.11  ? 258 VAL B C   1 
ATOM   7494  O  O   . VAL C 2 312 ? 143.410 132.053 152.582 1.00 51.98  ? 258 VAL B O   1 
ATOM   7495  C  CB  . VAL C 2 312 ? 145.123 131.919 155.466 1.00 51.91  ? 258 VAL B CB  1 
ATOM   7496  C  CG1 . VAL C 2 312 ? 145.656 130.860 154.531 1.00 49.32  ? 258 VAL B CG1 1 
ATOM   7497  C  CG2 . VAL C 2 312 ? 146.268 132.683 156.080 1.00 52.94  ? 258 VAL B CG2 1 
ATOM   7498  N  N   . LEU C 2 313 ? 142.174 131.547 154.394 1.00 52.86  ? 259 LEU B N   1 
ATOM   7499  C  CA  . LEU C 2 313 ? 141.205 130.820 153.583 1.00 52.44  ? 259 LEU B CA  1 
ATOM   7500  C  C   . LEU C 2 313 ? 140.505 131.743 152.593 1.00 52.27  ? 259 LEU B C   1 
ATOM   7501  O  O   . LEU C 2 313 ? 140.335 131.390 151.418 1.00 54.15  ? 259 LEU B O   1 
ATOM   7502  C  CB  . LEU C 2 313 ? 140.183 130.124 154.477 1.00 54.69  ? 259 LEU B CB  1 
ATOM   7503  C  CG  . LEU C 2 313 ? 140.688 128.953 155.310 1.00 50.18  ? 259 LEU B CG  1 
ATOM   7504  C  CD1 . LEU C 2 313 ? 139.520 128.285 155.995 1.00 53.46  ? 259 LEU B CD1 1 
ATOM   7505  C  CD2 . LEU C 2 313 ? 141.432 127.976 154.439 1.00 46.29  ? 259 LEU B CD2 1 
ATOM   7506  N  N   . THR C 2 314 ? 140.101 132.934 153.042 1.00 50.33  ? 260 THR B N   1 
ATOM   7507  C  CA  . THR C 2 314 ? 139.410 133.848 152.145 1.00 49.83  ? 260 THR B CA  1 
ATOM   7508  C  C   . THR C 2 314 ? 140.317 134.278 151.004 1.00 52.93  ? 260 THR B C   1 
ATOM   7509  O  O   . THR C 2 314 ? 139.880 134.349 149.852 1.00 55.51  ? 260 THR B O   1 
ATOM   7510  C  CB  . THR C 2 314 ? 138.901 135.062 152.917 1.00 51.51  ? 260 THR B CB  1 
ATOM   7511  O  OG1 . THR C 2 314 ? 138.377 134.635 154.178 1.00 56.09  ? 260 THR B OG1 1 
ATOM   7512  C  CG2 . THR C 2 314 ? 137.798 135.746 152.146 1.00 49.82  ? 260 THR B CG2 1 
ATOM   7513  N  N   . MET C 2 315 ? 141.588 134.553 151.300 1.00 52.53  ? 261 MET B N   1 
ATOM   7514  C  CA  . MET C 2 315 ? 142.518 134.981 150.262 1.00 50.50  ? 261 MET B CA  1 
ATOM   7515  C  C   . MET C 2 315 ? 142.748 133.882 149.235 1.00 51.38  ? 261 MET B C   1 
ATOM   7516  O  O   . MET C 2 315 ? 142.732 134.144 148.027 1.00 52.79  ? 261 MET B O   1 
ATOM   7517  C  CB  . MET C 2 315 ? 143.837 135.410 150.897 1.00 47.83  ? 261 MET B CB  1 
ATOM   7518  C  CG  . MET C 2 315 ? 144.830 135.988 149.923 1.00 52.53  ? 261 MET B CG  1 
ATOM   7519  S  SD  . MET C 2 315 ? 144.244 137.506 149.163 1.00 74.18  ? 261 MET B SD  1 
ATOM   7520  C  CE  . MET C 2 315 ? 144.369 138.636 150.537 1.00 54.16  ? 261 MET B CE  1 
ATOM   7521  N  N   . THR C 2 316 ? 142.965 132.645 149.688 1.00 51.12  ? 262 THR B N   1 
ATOM   7522  C  CA  . THR C 2 316 ? 143.175 131.560 148.734 1.00 47.24  ? 262 THR B CA  1 
ATOM   7523  C  C   . THR C 2 316 ? 141.942 131.344 147.871 1.00 47.70  ? 262 THR B C   1 
ATOM   7524  O  O   . THR C 2 316 ? 142.055 131.121 146.659 1.00 50.08  ? 262 THR B O   1 
ATOM   7525  C  CB  . THR C 2 316 ? 143.548 130.268 149.454 1.00 49.02  ? 262 THR B CB  1 
ATOM   7526  O  OG1 . THR C 2 316 ? 142.639 130.045 150.536 1.00 62.12  ? 262 THR B OG1 1 
ATOM   7527  C  CG2 . THR C 2 316 ? 144.942 130.354 149.992 1.00 46.41  ? 262 THR B CG2 1 
ATOM   7528  N  N   . THR C 2 317 ? 140.752 131.400 148.477 1.00 49.40  ? 263 THR B N   1 
ATOM   7529  C  CA  . THR C 2 317 ? 139.530 131.212 147.704 1.00 50.53  ? 263 THR B CA  1 
ATOM   7530  C  C   . THR C 2 317 ? 139.341 132.330 146.689 1.00 51.82  ? 263 THR B C   1 
ATOM   7531  O  O   . THR C 2 317 ? 138.931 132.081 145.552 1.00 55.51  ? 263 THR B O   1 
ATOM   7532  C  CB  . THR C 2 317 ? 138.329 131.119 148.639 1.00 50.75  ? 263 THR B CB  1 
ATOM   7533  O  OG1 . THR C 2 317 ? 138.592 130.136 149.645 1.00 54.95  ? 263 THR B OG1 1 
ATOM   7534  C  CG2 . THR C 2 317 ? 137.101 130.702 147.873 1.00 49.79  ? 263 THR B CG2 1 
ATOM   7535  N  N   . ILE C 2 318 ? 139.651 133.568 147.078 1.00 50.90  ? 264 ILE B N   1 
ATOM   7536  C  CA  . ILE C 2 318 ? 139.558 134.690 146.150 1.00 48.76  ? 264 ILE B CA  1 
ATOM   7537  C  C   . ILE C 2 318 ? 140.512 134.497 144.981 1.00 51.36  ? 264 ILE B C   1 
ATOM   7538  O  O   . ILE C 2 318 ? 140.150 134.729 143.823 1.00 55.12  ? 264 ILE B O   1 
ATOM   7539  C  CB  . ILE C 2 318 ? 139.832 136.014 146.886 1.00 49.51  ? 264 ILE B CB  1 
ATOM   7540  C  CG1 . ILE C 2 318 ? 138.655 136.375 147.790 1.00 49.05  ? 264 ILE B CG1 1 
ATOM   7541  C  CG2 . ILE C 2 318 ? 140.108 137.126 145.899 1.00 51.61  ? 264 ILE B CG2 1 
ATOM   7542  C  CD1 . ILE C 2 318 ? 138.902 137.584 148.652 1.00 49.85  ? 264 ILE B CD1 1 
ATOM   7543  N  N   . ASN C 2 319 ? 141.747 134.078 145.263 1.00 50.46  ? 265 ASN B N   1 
ATOM   7544  C  CA  . ASN C 2 319 ? 142.723 133.899 144.192 1.00 48.50  ? 265 ASN B CA  1 
ATOM   7545  C  C   . ASN C 2 319 ? 142.305 132.792 143.233 1.00 52.66  ? 265 ASN B C   1 
ATOM   7546  O  O   . ASN C 2 319 ? 142.409 132.951 142.010 1.00 56.70  ? 265 ASN B O   1 
ATOM   7547  C  CB  . ASN C 2 319 ? 144.100 133.608 144.780 1.00 45.79  ? 265 ASN B CB  1 
ATOM   7548  C  CG  . ASN C 2 319 ? 144.665 134.782 145.541 1.00 52.14  ? 265 ASN B CG  1 
ATOM   7549  O  OD1 . ASN C 2 319 ? 143.940 135.699 145.920 1.00 54.00  ? 265 ASN B OD1 1 
ATOM   7550  N  ND2 . ASN C 2 319 ? 145.968 134.762 145.772 1.00 54.77  ? 265 ASN B ND2 1 
ATOM   7551  N  N   . THR C 2 320 ? 141.824 131.664 143.760 1.00 51.46  ? 266 THR B N   1 
ATOM   7552  C  CA  . THR C 2 320 ? 141.393 130.585 142.874 1.00 51.74  ? 266 THR B CA  1 
ATOM   7553  C  C   . THR C 2 320 ? 140.167 130.991 142.065 1.00 55.88  ? 266 THR B C   1 
ATOM   7554  O  O   . THR C 2 320 ? 140.062 130.661 140.876 1.00 61.05  ? 266 THR B O   1 
ATOM   7555  C  CB  . THR C 2 320 ? 141.119 129.310 143.667 1.00 53.12  ? 266 THR B CB  1 
ATOM   7556  O  OG1 . THR C 2 320 ? 140.051 129.531 144.592 1.00 59.90  ? 266 THR B OG1 1 
ATOM   7557  C  CG2 . THR C 2 320 ? 142.359 128.886 144.416 1.00 49.82  ? 266 THR B CG2 1 
ATOM   7558  N  N   . HIS C 2 321 ? 139.235 131.720 142.680 1.00 53.50  ? 267 HIS B N   1 
ATOM   7559  C  CA  . HIS C 2 321 ? 138.067 132.178 141.940 1.00 57.05  ? 267 HIS B CA  1 
ATOM   7560  C  C   . HIS C 2 321 ? 138.457 133.143 140.830 1.00 60.52  ? 267 HIS B C   1 
ATOM   7561  O  O   . HIS C 2 321 ? 137.942 133.050 139.712 1.00 64.32  ? 267 HIS B O   1 
ATOM   7562  C  CB  . HIS C 2 321 ? 137.067 132.830 142.887 1.00 60.11  ? 267 HIS B CB  1 
ATOM   7563  C  CG  . HIS C 2 321 ? 135.911 133.471 142.188 1.00 72.02  ? 267 HIS B CG  1 
ATOM   7564  N  ND1 . HIS C 2 321 ? 135.813 134.833 142.009 1.00 71.79  ? 267 HIS B ND1 1 
ATOM   7565  C  CD2 . HIS C 2 321 ? 134.808 132.936 141.616 1.00 77.13  ? 267 HIS B CD2 1 
ATOM   7566  C  CE1 . HIS C 2 321 ? 134.695 135.111 141.363 1.00 75.21  ? 267 HIS B CE1 1 
ATOM   7567  N  NE2 . HIS C 2 321 ? 134.067 133.976 141.113 1.00 81.39  ? 267 HIS B NE2 1 
ATOM   7568  N  N   . LEU C 2 322 ? 139.365 134.078 141.116 1.00 59.51  ? 268 LEU B N   1 
ATOM   7569  C  CA  . LEU C 2 322 ? 139.789 135.013 140.081 1.00 58.11  ? 268 LEU B CA  1 
ATOM   7570  C  C   . LEU C 2 322 ? 140.541 134.306 138.968 1.00 59.68  ? 268 LEU B C   1 
ATOM   7571  O  O   . LEU C 2 322 ? 140.423 134.693 137.803 1.00 62.51  ? 268 LEU B O   1 
ATOM   7572  C  CB  . LEU C 2 322 ? 140.647 136.122 140.679 1.00 56.66  ? 268 LEU B CB  1 
ATOM   7573  C  CG  . LEU C 2 322 ? 139.852 137.174 141.441 1.00 56.39  ? 268 LEU B CG  1 
ATOM   7574  C  CD1 . LEU C 2 322 ? 140.751 138.318 141.846 1.00 57.35  ? 268 LEU B CD1 1 
ATOM   7575  C  CD2 . LEU C 2 322 ? 138.702 137.666 140.590 1.00 58.73  ? 268 LEU B CD2 1 
ATOM   7576  N  N   . ARG C 2 323 ? 141.317 133.275 139.300 1.00 60.58  ? 269 ARG B N   1 
ATOM   7577  C  CA  . ARG C 2 323 ? 141.904 132.449 138.254 1.00 59.77  ? 269 ARG B CA  1 
ATOM   7578  C  C   . ARG C 2 323 ? 140.820 131.815 137.396 1.00 60.51  ? 269 ARG B C   1 
ATOM   7579  O  O   . ARG C 2 323 ? 140.965 131.710 136.174 1.00 61.04  ? 269 ARG B O   1 
ATOM   7580  C  CB  . ARG C 2 323 ? 142.794 131.370 138.865 1.00 55.39  ? 269 ARG B CB  1 
ATOM   7581  C  CG  . ARG C 2 323 ? 143.294 130.354 137.855 1.00 54.01  ? 269 ARG B CG  1 
ATOM   7582  C  CD  . ARG C 2 323 ? 144.254 129.372 138.485 1.00 55.63  ? 269 ARG B CD  1 
ATOM   7583  N  NE  . ARG C 2 323 ? 144.850 128.489 137.492 1.00 60.50  ? 269 ARG B NE  1 
ATOM   7584  C  CZ  . ARG C 2 323 ? 145.842 127.646 137.740 1.00 61.83  ? 269 ARG B CZ  1 
ATOM   7585  N  NH1 . ARG C 2 323 ? 146.374 127.541 138.944 1.00 65.67  ? 269 ARG B NH1 1 
ATOM   7586  N  NH2 . ARG C 2 323 ? 146.313 126.891 136.753 1.00 57.76  ? 269 ARG B NH2 1 
ATOM   7587  N  N   . GLU C 2 324 ? 139.727 131.383 138.023 1.00 62.87  ? 270 GLU B N   1 
ATOM   7588  C  CA  . GLU C 2 324 ? 138.661 130.733 137.268 1.00 64.89  ? 270 GLU B CA  1 
ATOM   7589  C  C   . GLU C 2 324 ? 137.927 131.717 136.363 1.00 67.89  ? 270 GLU B C   1 
ATOM   7590  O  O   . GLU C 2 324 ? 137.534 131.362 135.247 1.00 73.44  ? 270 GLU B O   1 
ATOM   7591  C  CB  . GLU C 2 324 ? 137.683 130.056 138.224 1.00 67.79  ? 270 GLU B CB  1 
ATOM   7592  C  CG  . GLU C 2 324 ? 136.914 128.907 137.606 1.00 74.57  ? 270 GLU B CG  1 
ATOM   7593  C  CD  . GLU C 2 324 ? 137.816 127.760 137.203 1.00 82.51  ? 270 GLU B CD  1 
ATOM   7594  O  OE1 . GLU C 2 324 ? 138.888 127.601 137.820 1.00 80.50  ? 270 GLU B OE1 1 
ATOM   7595  O  OE2 . GLU C 2 324 ? 137.458 127.020 136.265 1.00 88.28  ? 270 GLU B OE2 1 
ATOM   7596  N  N   . THR C 2 325 ? 137.730 132.953 136.819 1.00 67.62  ? 271 THR B N   1 
ATOM   7597  C  CA  . THR C 2 325 ? 136.877 133.890 136.095 1.00 68.12  ? 271 THR B CA  1 
ATOM   7598  C  C   . THR C 2 325 ? 137.631 134.778 135.115 1.00 67.47  ? 271 THR B C   1 
ATOM   7599  O  O   . THR C 2 325 ? 137.067 135.153 134.084 1.00 69.25  ? 271 THR B O   1 
ATOM   7600  C  CB  . THR C 2 325 ? 136.106 134.774 137.075 1.00 71.10  ? 271 THR B CB  1 
ATOM   7601  O  OG1 . THR C 2 325 ? 137.025 135.531 137.870 1.00 71.96  ? 271 THR B OG1 1 
ATOM   7602  C  CG2 . THR C 2 325 ? 135.233 133.920 137.978 1.00 67.84  ? 271 THR B CG2 1 
ATOM   7603  N  N   . LEU C 2 326 ? 138.882 135.124 135.399 1.00 69.35  ? 272 LEU B N   1 
ATOM   7604  C  CA  . LEU C 2 326 ? 139.647 135.948 134.479 1.00 69.79  ? 272 LEU B CA  1 
ATOM   7605  C  C   . LEU C 2 326 ? 139.881 135.195 133.169 1.00 73.79  ? 272 LEU B C   1 
ATOM   7606  O  O   . LEU C 2 326 ? 139.889 133.962 133.150 1.00 74.74  ? 272 LEU B O   1 
ATOM   7607  C  CB  . LEU C 2 326 ? 140.983 136.340 135.104 1.00 69.27  ? 272 LEU B CB  1 
ATOM   7608  C  CG  . LEU C 2 326 ? 141.137 137.803 135.519 1.00 68.25  ? 272 LEU B CG  1 
ATOM   7609  C  CD1 . LEU C 2 326 ? 139.972 138.253 136.374 1.00 64.15  ? 272 LEU B CD1 1 
ATOM   7610  C  CD2 . LEU C 2 326 ? 142.440 138.003 136.260 1.00 65.39  ? 272 LEU B CD2 1 
ATOM   7611  N  N   . PRO C 2 327 ? 140.048 135.911 132.056 1.00 77.92  ? 273 PRO B N   1 
ATOM   7612  C  CA  . PRO C 2 327 ? 140.245 135.233 130.770 1.00 76.03  ? 273 PRO B CA  1 
ATOM   7613  C  C   . PRO C 2 327 ? 141.474 134.337 130.800 1.00 77.02  ? 273 PRO B C   1 
ATOM   7614  O  O   . PRO C 2 327 ? 142.513 134.693 131.357 1.00 76.23  ? 273 PRO B O   1 
ATOM   7615  C  CB  . PRO C 2 327 ? 140.410 136.392 129.782 1.00 73.02  ? 273 PRO B CB  1 
ATOM   7616  C  CG  . PRO C 2 327 ? 140.833 137.549 130.619 1.00 68.46  ? 273 PRO B CG  1 
ATOM   7617  C  CD  . PRO C 2 327 ? 140.109 137.374 131.913 1.00 72.25  ? 273 PRO B CD  1 
ATOM   7618  N  N   . LYS C 2 328 ? 141.348 133.162 130.186 1.00 73.53  ? 274 LYS B N   1 
ATOM   7619  C  CA  . LYS C 2 328 ? 142.363 132.117 130.299 1.00 73.79  ? 274 LYS B CA  1 
ATOM   7620  C  C   . LYS C 2 328 ? 143.557 132.482 129.424 1.00 73.44  ? 274 LYS B C   1 
ATOM   7621  O  O   . LYS C 2 328 ? 143.644 132.141 128.243 1.00 76.12  ? 274 LYS B O   1 
ATOM   7622  C  CB  . LYS C 2 328 ? 141.776 130.763 129.933 1.00 76.11  ? 274 LYS B CB  1 
ATOM   7623  C  CG  . LYS C 2 328 ? 140.738 130.282 130.923 1.00 80.51  ? 274 LYS B CG  1 
ATOM   7624  C  CD  . LYS C 2 328 ? 140.316 128.850 130.656 1.00 91.43  ? 274 LYS B CD  1 
ATOM   7625  C  CE  . LYS C 2 328 ? 139.271 128.397 131.664 1.00 94.29  ? 274 LYS B CE  1 
ATOM   7626  N  NZ  . LYS C 2 328 ? 138.859 126.987 131.436 1.00 99.52  ? 274 LYS B NZ  1 
ATOM   7627  N  N   . ILE C 2 329 ? 144.495 133.194 130.031 1.00 69.19  ? 275 ILE B N   1 
ATOM   7628  C  CA  . ILE C 2 329 ? 145.732 133.617 129.386 1.00 67.88  ? 275 ILE B CA  1 
ATOM   7629  C  C   . ILE C 2 329 ? 146.894 133.042 130.187 1.00 66.71  ? 275 ILE B C   1 
ATOM   7630  O  O   . ILE C 2 329 ? 147.232 133.580 131.249 1.00 69.06  ? 275 ILE B O   1 
ATOM   7631  C  CB  . ILE C 2 329 ? 145.825 135.146 129.294 1.00 69.78  ? 275 ILE B CB  1 
ATOM   7632  C  CG1 . ILE C 2 329 ? 144.657 135.685 128.475 1.00 70.20  ? 275 ILE B CG1 1 
ATOM   7633  C  CG2 . ILE C 2 329 ? 147.138 135.554 128.672 1.00 66.41  ? 275 ILE B CG2 1 
ATOM   7634  C  CD1 . ILE C 2 329 ? 144.742 137.148 128.202 1.00 65.20  ? 275 ILE B CD1 1 
ATOM   7635  N  N   . PRO C 2 330 ? 147.528 131.974 129.730 1.00 61.23  ? 276 PRO B N   1 
ATOM   7636  C  CA  . PRO C 2 330 ? 148.524 131.275 130.559 1.00 57.91  ? 276 PRO B CA  1 
ATOM   7637  C  C   . PRO C 2 330 ? 149.906 131.922 130.551 1.00 58.17  ? 276 PRO B C   1 
ATOM   7638  O  O   . PRO C 2 330 ? 150.911 131.331 130.149 1.00 60.02  ? 276 PRO B O   1 
ATOM   7639  C  CB  . PRO C 2 330 ? 148.527 129.876 129.944 1.00 56.03  ? 276 PRO B CB  1 
ATOM   7640  C  CG  . PRO C 2 330 ? 148.231 130.118 128.514 1.00 62.59  ? 276 PRO B CG  1 
ATOM   7641  C  CD  . PRO C 2 330 ? 147.278 131.274 128.461 1.00 64.17  ? 276 PRO B CD  1 
ATOM   7642  N  N   . TYR C 2 331 ? 149.974 133.164 131.017 1.00 56.96  ? 277 TYR B N   1 
ATOM   7643  C  CA  . TYR C 2 331 ? 151.254 133.754 131.382 1.00 56.29  ? 277 TYR B CA  1 
ATOM   7644  C  C   . TYR C 2 331 ? 151.006 134.819 132.435 1.00 53.44  ? 277 TYR B C   1 
ATOM   7645  O  O   . TYR C 2 331 ? 149.865 135.192 132.708 1.00 56.69  ? 277 TYR B O   1 
ATOM   7646  C  CB  . TYR C 2 331 ? 152.016 134.319 130.175 1.00 57.73  ? 277 TYR B CB  1 
ATOM   7647  C  CG  . TYR C 2 331 ? 151.294 135.331 129.314 1.00 60.20  ? 277 TYR B CG  1 
ATOM   7648  C  CD1 . TYR C 2 331 ? 151.103 136.635 129.745 1.00 60.40  ? 277 TYR B CD1 1 
ATOM   7649  C  CD2 . TYR C 2 331 ? 150.860 134.996 128.044 1.00 61.94  ? 277 TYR B CD2 1 
ATOM   7650  C  CE1 . TYR C 2 331 ? 150.466 137.560 128.949 1.00 58.67  ? 277 TYR B CE1 1 
ATOM   7651  C  CE2 . TYR C 2 331 ? 150.225 135.914 127.245 1.00 65.40  ? 277 TYR B CE2 1 
ATOM   7652  C  CZ  . TYR C 2 331 ? 150.031 137.193 127.702 1.00 62.14  ? 277 TYR B CZ  1 
ATOM   7653  O  OH  . TYR C 2 331 ? 149.400 138.105 126.901 1.00 61.33  ? 277 TYR B OH  1 
ATOM   7654  N  N   . VAL C 2 332 ? 152.096 135.281 133.043 1.00 47.55  ? 278 VAL B N   1 
ATOM   7655  C  CA  . VAL C 2 332 ? 151.997 136.163 134.196 1.00 47.26  ? 278 VAL B CA  1 
ATOM   7656  C  C   . VAL C 2 332 ? 151.558 137.550 133.751 1.00 50.04  ? 278 VAL B C   1 
ATOM   7657  O  O   . VAL C 2 332 ? 152.139 138.140 132.833 1.00 52.95  ? 278 VAL B O   1 
ATOM   7658  C  CB  . VAL C 2 332 ? 153.336 136.219 134.941 1.00 46.82  ? 278 VAL B CB  1 
ATOM   7659  C  CG1 . VAL C 2 332 ? 153.202 137.029 136.210 1.00 48.20  ? 278 VAL B CG1 1 
ATOM   7660  C  CG2 . VAL C 2 332 ? 153.811 134.827 135.251 1.00 48.15  ? 278 VAL B CG2 1 
ATOM   7661  N  N   . LYS C 2 333 ? 150.535 138.077 134.410 1.00 51.10  ? 279 LYS B N   1 
ATOM   7662  C  CA  . LYS C 2 333 ? 150.027 139.420 134.208 1.00 49.58  ? 279 LYS B CA  1 
ATOM   7663  C  C   . LYS C 2 333 ? 150.340 140.259 135.444 1.00 55.64  ? 279 LYS B C   1 
ATOM   7664  O  O   . LYS C 2 333 ? 151.027 139.811 136.366 1.00 61.39  ? 279 LYS B O   1 
ATOM   7665  C  CB  . LYS C 2 333 ? 148.531 139.370 133.910 1.00 49.65  ? 279 LYS B CB  1 
ATOM   7666  C  CG  . LYS C 2 333 ? 148.182 138.570 132.674 1.00 53.25  ? 279 LYS B CG  1 
ATOM   7667  C  CD  . LYS C 2 333 ? 146.684 138.505 132.458 1.00 54.78  ? 279 LYS B CD  1 
ATOM   7668  C  CE  . LYS C 2 333 ? 146.001 137.663 133.514 1.00 56.40  ? 279 LYS B CE  1 
ATOM   7669  N  NZ  . LYS C 2 333 ? 146.428 136.241 133.455 1.00 55.03  ? 279 LYS B NZ  1 
ATOM   7670  N  N   . ALA C 2 334 ? 149.849 141.497 135.458 1.00 54.49  ? 280 ALA B N   1 
ATOM   7671  C  CA  . ALA C 2 334 ? 150.086 142.361 136.610 1.00 57.26  ? 280 ALA B CA  1 
ATOM   7672  C  C   . ALA C 2 334 ? 149.223 141.955 137.798 1.00 56.59  ? 280 ALA B C   1 
ATOM   7673  O  O   . ALA C 2 334 ? 149.696 141.922 138.943 1.00 56.79  ? 280 ALA B O   1 
ATOM   7674  C  CB  . ALA C 2 334 ? 149.821 143.814 136.233 1.00 57.35  ? 280 ALA B CB  1 
ATOM   7675  N  N   . ILE C 2 335 ? 147.953 141.645 137.543 1.00 56.32  ? 281 ILE B N   1 
ATOM   7676  C  CA  . ILE C 2 335 ? 147.032 141.353 138.630 1.00 56.09  ? 281 ILE B CA  1 
ATOM   7677  C  C   . ILE C 2 335 ? 147.401 140.048 139.322 1.00 58.05  ? 281 ILE B C   1 
ATOM   7678  O  O   . ILE C 2 335 ? 147.171 139.892 140.527 1.00 62.83  ? 281 ILE B O   1 
ATOM   7679  C  CB  . ILE C 2 335 ? 145.589 141.350 138.103 1.00 52.65  ? 281 ILE B CB  1 
ATOM   7680  C  CG1 . ILE C 2 335 ? 144.605 141.213 139.259 1.00 57.09  ? 281 ILE B CG1 1 
ATOM   7681  C  CG2 . ILE C 2 335 ? 145.393 140.255 137.076 1.00 50.28  ? 281 ILE B CG2 1 
ATOM   7682  C  CD1 . ILE C 2 335 ? 143.183 141.370 138.845 1.00 59.67  ? 281 ILE B CD1 1 
ATOM   7683  N  N   . ASP C 2 336 ? 147.988 139.099 138.592 1.00 55.67  ? 282 ASP B N   1 
ATOM   7684  C  CA  . ASP C 2 336 ? 148.461 137.874 139.225 1.00 54.93  ? 282 ASP B CA  1 
ATOM   7685  C  C   . ASP C 2 336 ? 149.527 138.174 140.265 1.00 53.97  ? 282 ASP B C   1 
ATOM   7686  O  O   . ASP C 2 336 ? 149.495 137.632 141.377 1.00 56.14  ? 282 ASP B O   1 
ATOM   7687  C  CB  . ASP C 2 336 ? 149.000 136.917 138.169 1.00 57.06  ? 282 ASP B CB  1 
ATOM   7688  C  CG  . ASP C 2 336 ? 147.938 136.478 137.195 1.00 67.71  ? 282 ASP B CG  1 
ATOM   7689  O  OD1 . ASP C 2 336 ? 146.772 136.345 137.617 1.00 77.72  ? 282 ASP B OD1 1 
ATOM   7690  O  OD2 . ASP C 2 336 ? 148.263 136.275 136.009 1.00 63.50  ? 282 ASP B OD2 1 
ATOM   7691  N  N   . MET C 2 337 ? 150.468 139.055 139.932 1.00 54.95  ? 283 MET B N   1 
ATOM   7692  C  CA  . MET C 2 337 ? 151.489 139.433 140.895 1.00 54.08  ? 283 MET B CA  1 
ATOM   7693  C  C   . MET C 2 337 ? 150.909 140.240 142.049 1.00 51.77  ? 283 MET B C   1 
ATOM   7694  O  O   . MET C 2 337 ? 151.373 140.104 143.183 1.00 54.08  ? 283 MET B O   1 
ATOM   7695  C  CB  . MET C 2 337 ? 152.606 140.201 140.197 1.00 58.29  ? 283 MET B CB  1 
ATOM   7696  C  CG  . MET C 2 337 ? 153.390 139.349 139.222 1.00 63.09  ? 283 MET B CG  1 
ATOM   7697  S  SD  . MET C 2 337 ? 155.052 139.967 138.917 1.00 104.07 ? 283 MET B SD  1 
ATOM   7698  C  CE  . MET C 2 337 ? 154.702 141.583 138.235 1.00 90.19  ? 283 MET B CE  1 
ATOM   7699  N  N   . TYR C 2 338 ? 149.895 141.070 141.798 1.00 50.51  ? 284 TYR B N   1 
ATOM   7700  C  CA  . TYR C 2 338 ? 149.264 141.784 142.906 1.00 50.20  ? 284 TYR B CA  1 
ATOM   7701  C  C   . TYR C 2 338 ? 148.616 140.814 143.889 1.00 52.38  ? 284 TYR B C   1 
ATOM   7702  O  O   . TYR C 2 338 ? 148.778 140.942 145.111 1.00 57.02  ? 284 TYR B O   1 
ATOM   7703  C  CB  . TYR C 2 338 ? 148.231 142.775 142.383 1.00 54.69  ? 284 TYR B CB  1 
ATOM   7704  C  CG  . TYR C 2 338 ? 147.747 143.749 143.432 1.00 58.95  ? 284 TYR B CG  1 
ATOM   7705  C  CD1 . TYR C 2 338 ? 148.454 144.908 143.705 1.00 63.37  ? 284 TYR B CD1 1 
ATOM   7706  C  CD2 . TYR C 2 338 ? 146.588 143.509 144.148 1.00 57.62  ? 284 TYR B CD2 1 
ATOM   7707  C  CE1 . TYR C 2 338 ? 148.022 145.797 144.656 1.00 62.43  ? 284 TYR B CE1 1 
ATOM   7708  C  CE2 . TYR C 2 338 ? 146.149 144.395 145.103 1.00 59.60  ? 284 TYR B CE2 1 
ATOM   7709  C  CZ  . TYR C 2 338 ? 146.871 145.536 145.352 1.00 62.46  ? 284 TYR B CZ  1 
ATOM   7710  O  OH  . TYR C 2 338 ? 146.442 146.427 146.304 1.00 71.39  ? 284 TYR B OH  1 
ATOM   7711  N  N   . LEU C 2 339 ? 147.872 139.835 143.371 1.00 50.20  ? 285 LEU B N   1 
ATOM   7712  C  CA  . LEU C 2 339 ? 147.235 138.853 144.242 1.00 48.18  ? 285 LEU B CA  1 
ATOM   7713  C  C   . LEU C 2 339 ? 148.272 138.026 144.986 1.00 50.14  ? 285 LEU B C   1 
ATOM   7714  O  O   . LEU C 2 339 ? 148.088 137.692 146.164 1.00 56.14  ? 285 LEU B O   1 
ATOM   7715  C  CB  . LEU C 2 339 ? 146.313 137.949 143.432 1.00 48.35  ? 285 LEU B CB  1 
ATOM   7716  C  CG  . LEU C 2 339 ? 145.187 138.646 142.672 1.00 50.64  ? 285 LEU B CG  1 
ATOM   7717  C  CD1 . LEU C 2 339 ? 144.297 137.628 142.005 1.00 49.28  ? 285 LEU B CD1 1 
ATOM   7718  C  CD2 . LEU C 2 339 ? 144.392 139.546 143.594 1.00 52.24  ? 285 LEU B CD2 1 
ATOM   7719  N  N   . MET C 2 340 ? 149.368 137.680 144.313 1.00 48.97  ? 286 MET B N   1 
ATOM   7720  C  CA  . MET C 2 340 ? 150.435 136.947 144.980 1.00 49.35  ? 286 MET B CA  1 
ATOM   7721  C  C   . MET C 2 340 ? 151.049 137.771 146.104 1.00 51.52  ? 286 MET B C   1 
ATOM   7722  O  O   . MET C 2 340 ? 151.364 137.237 147.173 1.00 55.15  ? 286 MET B O   1 
ATOM   7723  C  CB  . MET C 2 340 ? 151.496 136.538 143.964 1.00 49.80  ? 286 MET B CB  1 
ATOM   7724  C  CG  . MET C 2 340 ? 152.364 135.406 144.434 1.00 52.33  ? 286 MET B CG  1 
ATOM   7725  S  SD  . MET C 2 340 ? 151.355 134.064 145.066 1.00 71.59  ? 286 MET B SD  1 
ATOM   7726  C  CE  . MET C 2 340 ? 152.625 132.881 145.469 1.00 74.93  ? 286 MET B CE  1 
ATOM   7727  N  N   . GLY C 2 341 ? 151.224 139.074 145.885 1.00 47.71  ? 287 GLY B N   1 
ATOM   7728  C  CA  . GLY C 2 341 ? 151.737 139.930 146.943 1.00 48.73  ? 287 GLY B CA  1 
ATOM   7729  C  C   . GLY C 2 341 ? 150.807 140.004 148.138 1.00 50.07  ? 287 GLY B C   1 
ATOM   7730  O  O   . GLY C 2 341 ? 151.252 139.962 149.288 1.00 51.24  ? 287 GLY B O   1 
ATOM   7731  N  N   . CYS C 2 342 ? 149.502 140.108 147.885 1.00 50.21  ? 288 CYS B N   1 
ATOM   7732  C  CA  . CYS C 2 342 ? 148.549 140.116 148.993 1.00 50.16  ? 288 CYS B CA  1 
ATOM   7733  C  C   . CYS C 2 342 ? 148.604 138.809 149.779 1.00 51.59  ? 288 CYS B C   1 
ATOM   7734  O  O   . CYS C 2 342 ? 148.563 138.811 151.021 1.00 56.12  ? 288 CYS B O   1 
ATOM   7735  C  CB  . CYS C 2 342 ? 147.139 140.369 148.467 1.00 49.59  ? 288 CYS B CB  1 
ATOM   7736  S  SG  . CYS C 2 342 ? 146.916 141.963 147.656 1.00 53.18  ? 288 CYS B SG  1 
ATOM   7737  N  N   . PHE C 2 343 ? 148.692 137.682 149.070 1.00 51.11  ? 289 PHE B N   1 
ATOM   7738  C  CA  . PHE C 2 343 ? 148.794 136.390 149.740 1.00 49.71  ? 289 PHE B CA  1 
ATOM   7739  C  C   . PHE C 2 343 ? 150.059 136.307 150.582 1.00 49.46  ? 289 PHE B C   1 
ATOM   7740  O  O   . PHE C 2 343 ? 150.034 135.808 151.714 1.00 52.26  ? 289 PHE B O   1 
ATOM   7741  C  CB  . PHE C 2 343 ? 148.764 135.272 148.702 1.00 47.62  ? 289 PHE B CB  1 
ATOM   7742  C  CG  . PHE C 2 343 ? 148.856 133.898 149.283 1.00 52.23  ? 289 PHE B CG  1 
ATOM   7743  C  CD1 . PHE C 2 343 ? 147.747 133.291 149.832 1.00 52.48  ? 289 PHE B CD1 1 
ATOM   7744  C  CD2 . PHE C 2 343 ? 150.046 133.202 149.264 1.00 53.66  ? 289 PHE B CD2 1 
ATOM   7745  C  CE1 . PHE C 2 343 ? 147.830 132.030 150.359 1.00 48.40  ? 289 PHE B CE1 1 
ATOM   7746  C  CE2 . PHE C 2 343 ? 150.127 131.935 149.793 1.00 51.46  ? 289 PHE B CE2 1 
ATOM   7747  C  CZ  . PHE C 2 343 ? 149.018 131.350 150.338 1.00 46.00  ? 289 PHE B CZ  1 
ATOM   7748  N  N   . VAL C 2 344 ? 151.175 136.799 150.044 1.00 48.62  ? 290 VAL B N   1 
ATOM   7749  C  CA  . VAL C 2 344 ? 152.421 136.826 150.802 1.00 47.63  ? 290 VAL B CA  1 
ATOM   7750  C  C   . VAL C 2 344 ? 152.257 137.656 152.064 1.00 50.81  ? 290 VAL B C   1 
ATOM   7751  O  O   . VAL C 2 344 ? 152.776 137.303 153.127 1.00 55.39  ? 290 VAL B O   1 
ATOM   7752  C  CB  . VAL C 2 344 ? 153.568 137.359 149.926 1.00 45.09  ? 290 VAL B CB  1 
ATOM   7753  C  CG1 . VAL C 2 344 ? 154.792 137.625 150.767 1.00 44.20  ? 290 VAL B CG1 1 
ATOM   7754  C  CG2 . VAL C 2 344 ? 153.892 136.370 148.837 1.00 46.17  ? 290 VAL B CG2 1 
ATOM   7755  N  N   . PHE C 2 345 ? 151.539 138.774 151.969 1.00 50.74  ? 291 PHE B N   1 
ATOM   7756  C  CA  . PHE C 2 345 ? 151.381 139.631 153.140 1.00 51.00  ? 291 PHE B CA  1 
ATOM   7757  C  C   . PHE C 2 345 ? 150.566 138.953 154.235 1.00 51.41  ? 291 PHE B C   1 
ATOM   7758  O  O   . PHE C 2 345 ? 150.934 139.019 155.416 1.00 56.36  ? 291 PHE B O   1 
ATOM   7759  C  CB  . PHE C 2 345 ? 150.758 140.964 152.738 1.00 51.42  ? 291 PHE B CB  1 
ATOM   7760  C  CG  . PHE C 2 345 ? 151.768 142.037 152.479 1.00 54.50  ? 291 PHE B CG  1 
ATOM   7761  C  CD1 . PHE C 2 345 ? 152.232 142.827 153.510 1.00 60.69  ? 291 PHE B CD1 1 
ATOM   7762  C  CD2 . PHE C 2 345 ? 152.270 142.243 151.211 1.00 57.33  ? 291 PHE B CD2 1 
ATOM   7763  C  CE1 . PHE C 2 345 ? 153.166 143.809 153.278 1.00 65.47  ? 291 PHE B CE1 1 
ATOM   7764  C  CE2 . PHE C 2 345 ? 153.204 143.222 150.976 1.00 62.47  ? 291 PHE B CE2 1 
ATOM   7765  C  CZ  . PHE C 2 345 ? 153.653 144.006 152.011 1.00 65.39  ? 291 PHE B CZ  1 
ATOM   7766  N  N   . VAL C 2 346 ? 149.460 138.298 153.879 1.00 48.33  ? 292 VAL B N   1 
ATOM   7767  C  CA  . VAL C 2 346 ? 148.685 137.630 154.927 1.00 51.38  ? 292 VAL B CA  1 
ATOM   7768  C  C   . VAL C 2 346 ? 149.474 136.458 155.516 1.00 55.47  ? 292 VAL B C   1 
ATOM   7769  O  O   . VAL C 2 346 ? 149.427 136.202 156.730 1.00 60.42  ? 292 VAL B O   1 
ATOM   7770  C  CB  . VAL C 2 346 ? 147.295 137.204 154.413 1.00 46.84  ? 292 VAL B CB  1 
ATOM   7771  C  CG1 . VAL C 2 346 ? 146.608 138.367 153.742 1.00 51.22  ? 292 VAL B CG1 1 
ATOM   7772  C  CG2 . VAL C 2 346 ? 147.375 136.029 153.474 1.00 49.31  ? 292 VAL B CG2 1 
ATOM   7773  N  N   . PHE C 2 347 ? 150.238 135.752 154.680 1.00 53.33  ? 293 PHE B N   1 
ATOM   7774  C  CA  . PHE C 2 347 ? 151.082 134.672 155.179 1.00 51.67  ? 293 PHE B CA  1 
ATOM   7775  C  C   . PHE C 2 347 ? 152.129 135.199 156.155 1.00 56.80  ? 293 PHE B C   1 
ATOM   7776  O  O   . PHE C 2 347 ? 152.376 134.591 157.203 1.00 60.10  ? 293 PHE B O   1 
ATOM   7777  C  CB  . PHE C 2 347 ? 151.725 133.955 153.991 1.00 53.74  ? 293 PHE B CB  1 
ATOM   7778  C  CG  . PHE C 2 347 ? 152.893 133.089 154.347 1.00 62.31  ? 293 PHE B CG  1 
ATOM   7779  C  CD1 . PHE C 2 347 ? 152.701 131.807 154.822 1.00 63.43  ? 293 PHE B CD1 1 
ATOM   7780  C  CD2 . PHE C 2 347 ? 154.188 133.541 154.165 1.00 62.06  ? 293 PHE B CD2 1 
ATOM   7781  C  CE1 . PHE C 2 347 ? 153.774 131.005 155.134 1.00 65.85  ? 293 PHE B CE1 1 
ATOM   7782  C  CE2 . PHE C 2 347 ? 155.261 132.743 154.476 1.00 62.22  ? 293 PHE B CE2 1 
ATOM   7783  C  CZ  . PHE C 2 347 ? 155.055 131.474 154.963 1.00 66.99  ? 293 PHE B CZ  1 
ATOM   7784  N  N   . LEU C 2 348 ? 152.739 136.342 155.836 1.00 57.06  ? 294 LEU B N   1 
ATOM   7785  C  CA  . LEU C 2 348 ? 153.720 136.944 156.732 1.00 55.77  ? 294 LEU B CA  1 
ATOM   7786  C  C   . LEU C 2 348 ? 153.082 137.385 158.041 1.00 61.65  ? 294 LEU B C   1 
ATOM   7787  O  O   . LEU C 2 348 ? 153.708 137.289 159.099 1.00 66.67  ? 294 LEU B O   1 
ATOM   7788  C  CB  . LEU C 2 348 ? 154.401 138.128 156.053 1.00 53.37  ? 294 LEU B CB  1 
ATOM   7789  C  CG  . LEU C 2 348 ? 155.459 137.802 155.006 1.00 56.26  ? 294 LEU B CG  1 
ATOM   7790  C  CD1 . LEU C 2 348 ? 155.990 139.078 154.389 1.00 57.18  ? 294 LEU B CD1 1 
ATOM   7791  C  CD2 . LEU C 2 348 ? 156.584 137.004 155.631 1.00 54.94  ? 294 LEU B CD2 1 
ATOM   7792  N  N   . ALA C 2 349 ? 151.850 137.891 157.991 1.00 63.39  ? 295 ALA B N   1 
ATOM   7793  C  CA  . ALA C 2 349 ? 151.170 138.276 159.226 1.00 62.20  ? 295 ALA B CA  1 
ATOM   7794  C  C   . ALA C 2 349 ? 150.959 137.070 160.134 1.00 64.51  ? 295 ALA B C   1 
ATOM   7795  O  O   . ALA C 2 349 ? 151.223 137.125 161.345 1.00 66.52  ? 295 ALA B O   1 
ATOM   7796  C  CB  . ALA C 2 349 ? 149.836 138.943 158.904 1.00 57.95  ? 295 ALA B CB  1 
ATOM   7797  N  N   . LEU C 2 350 ? 150.492 135.960 159.559 1.00 62.89  ? 296 LEU B N   1 
ATOM   7798  C  CA  . LEU C 2 350 ? 150.315 134.751 160.358 1.00 62.36  ? 296 LEU B CA  1 
ATOM   7799  C  C   . LEU C 2 350 ? 151.647 134.262 160.921 1.00 63.92  ? 296 LEU B C   1 
ATOM   7800  O  O   . LEU C 2 350 ? 151.724 133.831 162.080 1.00 69.10  ? 296 LEU B O   1 
ATOM   7801  C  CB  . LEU C 2 350 ? 149.651 133.664 159.520 1.00 59.26  ? 296 LEU B CB  1 
ATOM   7802  C  CG  . LEU C 2 350 ? 149.160 132.431 160.273 1.00 59.12  ? 296 LEU B CG  1 
ATOM   7803  C  CD1 . LEU C 2 350 ? 148.102 132.818 161.277 1.00 63.32  ? 296 LEU B CD1 1 
ATOM   7804  C  CD2 . LEU C 2 350 ? 148.616 131.404 159.307 1.00 60.27  ? 296 LEU B CD2 1 
ATOM   7805  N  N   . LEU C 2 351 ? 152.708 134.326 160.114 1.00 61.46  ? 297 LEU B N   1 
ATOM   7806  C  CA  . LEU C 2 351 ? 154.027 133.912 160.584 1.00 62.10  ? 297 LEU B CA  1 
ATOM   7807  C  C   . LEU C 2 351 ? 154.506 134.787 161.737 1.00 69.17  ? 297 LEU B C   1 
ATOM   7808  O  O   . LEU C 2 351 ? 155.126 134.293 162.689 1.00 72.69  ? 297 LEU B O   1 
ATOM   7809  C  CB  . LEU C 2 351 ? 155.021 133.955 159.429 1.00 60.10  ? 297 LEU B CB  1 
ATOM   7810  C  CG  . LEU C 2 351 ? 156.440 133.479 159.716 1.00 65.10  ? 297 LEU B CG  1 
ATOM   7811  C  CD1 . LEU C 2 351 ? 156.461 131.975 159.863 1.00 68.59  ? 297 LEU B CD1 1 
ATOM   7812  C  CD2 . LEU C 2 351 ? 157.378 133.922 158.615 1.00 67.17  ? 297 LEU B CD2 1 
ATOM   7813  N  N   . GLU C 2 352 ? 154.243 136.093 161.659 1.00 71.36  ? 298 GLU B N   1 
ATOM   7814  C  CA  . GLU C 2 352 ? 154.601 136.994 162.749 1.00 73.46  ? 298 GLU B CA  1 
ATOM   7815  C  C   . GLU C 2 352 ? 153.863 136.627 164.025 1.00 75.90  ? 298 GLU B C   1 
ATOM   7816  O  O   . GLU C 2 352 ? 154.445 136.638 165.118 1.00 78.17  ? 298 GLU B O   1 
ATOM   7817  C  CB  . GLU C 2 352 ? 154.303 138.440 162.352 1.00 74.37  ? 298 GLU B CB  1 
ATOM   7818  C  CG  . GLU C 2 352 ? 154.419 139.451 163.485 1.00 77.39  ? 298 GLU B CG  1 
ATOM   7819  C  CD  . GLU C 2 352 ? 153.097 139.697 164.185 1.00 82.08  ? 298 GLU B CD  1 
ATOM   7820  O  OE1 . GLU C 2 352 ? 152.106 139.028 163.834 1.00 82.44  ? 298 GLU B OE1 1 
ATOM   7821  O  OE2 . GLU C 2 352 ? 153.048 140.558 165.086 1.00 84.51  ? 298 GLU B OE2 1 
ATOM   7822  N  N   . TYR C 2 353 ? 152.573 136.305 163.909 1.00 75.92  ? 299 TYR B N   1 
ATOM   7823  C  CA  . TYR C 2 353 ? 151.847 135.857 165.092 1.00 78.75  ? 299 TYR B CA  1 
ATOM   7824  C  C   . TYR C 2 353 ? 152.476 134.602 165.679 1.00 79.59  ? 299 TYR B C   1 
ATOM   7825  O  O   . TYR C 2 353 ? 152.591 134.471 166.903 1.00 82.21  ? 299 TYR B O   1 
ATOM   7826  C  CB  . TYR C 2 353 ? 150.380 135.587 164.772 1.00 80.82  ? 299 TYR B CB  1 
ATOM   7827  C  CG  . TYR C 2 353 ? 149.713 134.798 165.873 1.00 86.54  ? 299 TYR B CG  1 
ATOM   7828  C  CD1 . TYR C 2 353 ? 149.287 135.424 167.034 1.00 91.24  ? 299 TYR B CD1 1 
ATOM   7829  C  CD2 . TYR C 2 353 ? 149.533 133.426 165.766 1.00 83.75  ? 299 TYR B CD2 1 
ATOM   7830  C  CE1 . TYR C 2 353 ? 148.691 134.711 168.049 1.00 93.60  ? 299 TYR B CE1 1 
ATOM   7831  C  CE2 . TYR C 2 353 ? 148.939 132.706 166.778 1.00 89.35  ? 299 TYR B CE2 1 
ATOM   7832  C  CZ  . TYR C 2 353 ? 148.520 133.354 167.917 1.00 94.01  ? 299 TYR B CZ  1 
ATOM   7833  O  OH  . TYR C 2 353 ? 147.925 132.641 168.928 1.00 97.40  ? 299 TYR B OH  1 
ATOM   7834  N  N   . ALA C 2 354 ? 152.862 133.654 164.823 1.00 78.47  ? 300 ALA B N   1 
ATOM   7835  C  CA  . ALA C 2 354 ? 153.466 132.422 165.321 1.00 74.25  ? 300 ALA B CA  1 
ATOM   7836  C  C   . ALA C 2 354 ? 154.772 132.703 166.051 1.00 80.00  ? 300 ALA B C   1 
ATOM   7837  O  O   . ALA C 2 354 ? 155.043 132.118 167.106 1.00 85.79  ? 300 ALA B O   1 
ATOM   7838  C  CB  . ALA C 2 354 ? 153.697 131.444 164.172 1.00 71.64  ? 300 ALA B CB  1 
ATOM   7839  N  N   . PHE C 2 355 ? 155.594 133.599 165.506 1.00 81.84  ? 301 PHE B N   1 
ATOM   7840  C  CA  . PHE C 2 355 ? 156.848 133.945 166.170 1.00 84.56  ? 301 PHE B CA  1 
ATOM   7841  C  C   . PHE C 2 355 ? 156.598 134.601 167.522 1.00 87.33  ? 301 PHE B C   1 
ATOM   7842  O  O   . PHE C 2 355 ? 157.283 134.295 168.509 1.00 89.17  ? 301 PHE B O   1 
ATOM   7843  C  CB  . PHE C 2 355 ? 157.679 134.863 165.281 1.00 84.76  ? 301 PHE B CB  1 
ATOM   7844  C  CG  . PHE C 2 355 ? 158.985 135.270 165.890 1.00 92.82  ? 301 PHE B CG  1 
ATOM   7845  C  CD1 . PHE C 2 355 ? 159.985 134.337 166.099 1.00 96.76  ? 301 PHE B CD1 1 
ATOM   7846  C  CD2 . PHE C 2 355 ? 159.222 136.586 166.240 1.00 91.66  ? 301 PHE B CD2 1 
ATOM   7847  C  CE1 . PHE C 2 355 ? 161.191 134.706 166.655 1.00 96.75  ? 301 PHE B CE1 1 
ATOM   7848  C  CE2 . PHE C 2 355 ? 160.427 136.963 166.794 1.00 92.56  ? 301 PHE B CE2 1 
ATOM   7849  C  CZ  . PHE C 2 355 ? 161.413 136.022 167.003 1.00 96.00  ? 301 PHE B CZ  1 
ATOM   7850  N  N   . VAL C 2 356 ? 155.620 135.507 167.589 1.00 87.48  ? 302 VAL B N   1 
ATOM   7851  C  CA  . VAL C 2 356 ? 155.295 136.143 168.864 1.00 87.57  ? 302 VAL B CA  1 
ATOM   7852  C  C   . VAL C 2 356 ? 154.833 135.103 169.873 1.00 89.09  ? 302 VAL B C   1 
ATOM   7853  O  O   . VAL C 2 356 ? 155.248 135.117 171.037 1.00 93.50  ? 302 VAL B O   1 
ATOM   7854  C  CB  . VAL C 2 356 ? 154.240 137.244 168.662 1.00 85.86  ? 302 VAL B CB  1 
ATOM   7855  C  CG1 . VAL C 2 356 ? 153.633 137.637 169.990 1.00 87.29  ? 302 VAL B CG1 1 
ATOM   7856  C  CG2 . VAL C 2 356 ? 154.868 138.448 168.002 1.00 88.67  ? 302 VAL B CG2 1 
ATOM   7857  N  N   . ASN C 2 357 ? 153.974 134.180 169.441 1.00 90.11  ? 303 ASN B N   1 
ATOM   7858  C  CA  . ASN C 2 357 ? 153.514 133.117 170.326 1.00 92.68  ? 303 ASN B CA  1 
ATOM   7859  C  C   . ASN C 2 357 ? 154.676 132.257 170.798 1.00 93.06  ? 303 ASN B C   1 
ATOM   7860  O  O   . ASN C 2 357 ? 154.662 131.737 171.919 1.00 96.43  ? 303 ASN B O   1 
ATOM   7861  C  CB  . ASN C 2 357 ? 152.471 132.264 169.607 1.00 92.07  ? 303 ASN B CB  1 
ATOM   7862  C  CG  . ASN C 2 357 ? 151.967 131.119 170.453 1.00 96.56  ? 303 ASN B CG  1 
ATOM   7863  O  OD1 . ASN C 2 357 ? 152.629 130.092 170.589 1.00 89.93  ? 303 ASN B OD1 1 
ATOM   7864  N  ND2 . ASN C 2 357 ? 150.779 131.283 171.018 1.00 103.53 ? 303 ASN B ND2 1 
ATOM   7865  N  N   . TYR C 2 358 ? 155.686 132.084 169.948 1.00 91.53  ? 304 TYR B N   1 
ATOM   7866  C  CA  . TYR C 2 358 ? 156.836 131.270 170.321 1.00 92.09  ? 304 TYR B CA  1 
ATOM   7867  C  C   . TYR C 2 358 ? 157.699 131.959 171.370 1.00 93.01  ? 304 TYR B C   1 
ATOM   7868  O  O   . TYR C 2 358 ? 158.137 131.320 172.332 1.00 93.67  ? 304 TYR B O   1 
ATOM   7869  C  CB  . TYR C 2 358 ? 157.661 130.942 169.081 1.00 93.09  ? 304 TYR B CB  1 
ATOM   7870  C  CG  . TYR C 2 358 ? 159.027 130.375 169.373 1.00 95.91  ? 304 TYR B CG  1 
ATOM   7871  C  CD1 . TYR C 2 358 ? 159.173 129.111 169.921 1.00 93.63  ? 304 TYR B CD1 1 
ATOM   7872  C  CD2 . TYR C 2 358 ? 160.172 131.096 169.077 1.00 96.08  ? 304 TYR B CD2 1 
ATOM   7873  C  CE1 . TYR C 2 358 ? 160.420 128.588 170.180 1.00 95.39  ? 304 TYR B CE1 1 
ATOM   7874  C  CE2 . TYR C 2 358 ? 161.422 130.582 169.330 1.00 97.53  ? 304 TYR B CE2 1 
ATOM   7875  C  CZ  . TYR C 2 358 ? 161.543 129.327 169.881 1.00 99.15  ? 304 TYR B CZ  1 
ATOM   7876  O  OH  . TYR C 2 358 ? 162.793 128.813 170.134 1.00 98.81  ? 304 TYR B OH  1 
ATOM   7877  N  N   . ILE C 2 359 ? 157.957 133.255 171.208 1.00 94.74  ? 305 ILE B N   1 
ATOM   7878  C  CA  . ILE C 2 359 ? 158.894 133.930 172.103 1.00 97.60  ? 305 ILE B CA  1 
ATOM   7879  C  C   . ILE C 2 359 ? 158.174 134.532 173.301 1.00 101.95 ? 305 ILE B C   1 
ATOM   7880  O  O   . ILE C 2 359 ? 158.791 135.227 174.115 1.00 105.99 ? 305 ILE B O   1 
ATOM   7881  C  CB  . ILE C 2 359 ? 159.685 135.025 171.369 1.00 97.48  ? 305 ILE B CB  1 
ATOM   7882  C  CG1 . ILE C 2 359 ? 158.745 136.155 170.954 1.00 99.12  ? 305 ILE B CG1 1 
ATOM   7883  C  CG2 . ILE C 2 359 ? 160.408 134.454 170.169 1.00 95.80  ? 305 ILE B CG2 1 
ATOM   7884  C  CD1 . ILE C 2 359 ? 159.423 137.249 170.189 1.00 100.70 ? 305 ILE B CD1 1 
ATOM   7885  N  N   . PHE C 2 360 ? 156.870 134.278 173.423 1.00 102.12 ? 306 PHE B N   1 
ATOM   7886  C  CA  . PHE C 2 360 ? 156.092 134.960 174.453 1.00 105.48 ? 306 PHE B CA  1 
ATOM   7887  C  C   . PHE C 2 360 ? 156.556 134.587 175.856 1.00 110.77 ? 306 PHE B C   1 
ATOM   7888  O  O   . PHE C 2 360 ? 156.673 135.457 176.726 1.00 110.15 ? 306 PHE B O   1 
ATOM   7889  C  CB  . PHE C 2 360 ? 154.607 134.652 174.296 1.00 105.35 ? 306 PHE B CB  1 
ATOM   7890  C  CG  . PHE C 2 360 ? 153.759 135.252 175.372 1.00 107.83 ? 306 PHE B CG  1 
ATOM   7891  C  CD1 . PHE C 2 360 ? 153.365 136.573 175.298 1.00 108.39 ? 306 PHE B CD1 1 
ATOM   7892  C  CD2 . PHE C 2 360 ? 153.370 134.502 176.467 1.00 109.74 ? 306 PHE B CD2 1 
ATOM   7893  C  CE1 . PHE C 2 360 ? 152.591 137.134 176.289 1.00 108.78 ? 306 PHE B CE1 1 
ATOM   7894  C  CE2 . PHE C 2 360 ? 152.595 135.058 177.461 1.00 111.49 ? 306 PHE B CE2 1 
ATOM   7895  C  CZ  . PHE C 2 360 ? 152.207 136.377 177.373 1.00 110.95 ? 306 PHE B CZ  1 
ATOM   7896  N  N   . PHE C 2 361 ? 156.814 133.302 176.098 1.00 110.46 ? 307 PHE B N   1 
ATOM   7897  C  CA  . PHE C 2 361 ? 157.144 132.845 177.442 1.00 111.57 ? 307 PHE B CA  1 
ATOM   7898  C  C   . PHE C 2 361 ? 158.555 133.218 177.874 1.00 111.07 ? 307 PHE B C   1 
ATOM   7899  O  O   . PHE C 2 361 ? 158.890 133.034 179.049 1.00 109.56 ? 307 PHE B O   1 
ATOM   7900  C  CB  . PHE C 2 361 ? 156.952 131.333 177.537 1.00 111.47 ? 307 PHE B CB  1 
ATOM   7901  C  CG  . PHE C 2 361 ? 155.519 130.900 177.417 1.00 117.10 ? 307 PHE B CG  1 
ATOM   7902  C  CD1 . PHE C 2 361 ? 154.713 130.815 178.540 1.00 117.44 ? 307 PHE B CD1 1 
ATOM   7903  C  CD2 . PHE C 2 361 ? 154.975 130.587 176.180 1.00 118.04 ? 307 PHE B CD2 1 
ATOM   7904  C  CE1 . PHE C 2 361 ? 153.393 130.421 178.434 1.00 120.12 ? 307 PHE B CE1 1 
ATOM   7905  C  CE2 . PHE C 2 361 ? 153.654 130.193 176.069 1.00 117.31 ? 307 PHE B CE2 1 
ATOM   7906  C  CZ  . PHE C 2 361 ? 152.861 130.112 177.196 1.00 118.97 ? 307 PHE B CZ  1 
ATOM   7907  N  N   . SER C 2 362 ? 159.383 133.734 176.972 1.00 112.91 ? 308 SER B N   1 
ATOM   7908  C  CA  . SER C 2 362 ? 160.756 134.101 177.293 1.00 110.32 ? 308 SER B CA  1 
ATOM   7909  C  C   . SER C 2 362 ? 160.996 135.601 177.309 1.00 109.66 ? 308 SER B C   1 
ATOM   7910  O  O   . SER C 2 362 ? 161.720 136.093 178.176 1.00 107.23 ? 308 SER B O   1 
ATOM   7911  C  CB  . SER C 2 362 ? 161.721 133.451 176.297 1.00 111.92 ? 308 SER B CB  1 
ATOM   7912  O  OG  . SER C 2 362 ? 161.430 133.850 174.969 1.00 112.44 ? 308 SER B OG  1 
ATOM   7913  N  N   . GLN C 2 363 ? 160.420 136.343 176.367 1.00 112.81 ? 309 GLN B N   1 
ATOM   7914  C  CA  . GLN C 2 363 ? 160.593 137.792 176.277 1.00 114.57 ? 309 GLN B CA  1 
ATOM   7915  C  C   . GLN C 2 363 ? 159.235 138.455 176.076 1.00 115.00 ? 309 GLN B C   1 
ATOM   7916  O  O   . GLN C 2 363 ? 158.929 138.949 174.984 1.00 115.90 ? 309 GLN B O   1 
ATOM   7917  C  CB  . GLN C 2 363 ? 161.549 138.154 175.140 1.00 113.37 ? 309 GLN B CB  1 
ATOM   7918  C  CG  . GLN C 2 363 ? 162.928 137.530 175.241 1.00 114.41 ? 309 GLN B CG  1 
ATOM   7919  C  CD  . GLN C 2 363 ? 163.879 138.355 176.082 1.00 119.61 ? 309 GLN B CD  1 
ATOM   7920  O  OE1 . GLN C 2 363 ? 163.506 139.397 176.617 1.00 121.30 ? 309 GLN B OE1 1 
ATOM   7921  N  NE2 . GLN C 2 363 ? 165.119 137.893 176.198 1.00 120.92 ? 309 GLN B NE2 1 
ATOM   7922  N  N   . PRO C 2 364 ? 158.387 138.475 177.110 1.00 114.83 ? 310 PRO B N   1 
ATOM   7923  C  CA  . PRO C 2 364 ? 157.082 139.143 176.957 1.00 113.71 ? 310 PRO B CA  1 
ATOM   7924  C  C   . PRO C 2 364 ? 157.192 140.608 176.570 1.00 113.24 ? 310 PRO B C   1 
ATOM   7925  O  O   . PRO C 2 364 ? 156.402 141.091 175.746 1.00 109.13 ? 310 PRO B O   1 
ATOM   7926  C  CB  . PRO C 2 364 ? 156.440 138.966 178.339 1.00 110.82 ? 310 PRO B CB  1 
ATOM   7927  C  CG  . PRO C 2 364 ? 157.099 137.762 178.905 1.00 107.93 ? 310 PRO B CG  1 
ATOM   7928  C  CD  . PRO C 2 364 ? 158.515 137.820 178.422 1.00 111.28 ? 310 PRO B CD  1 
ATOM   7929  N  N   . ALA C 2 365 ? 158.160 141.332 177.136 1.00 112.38 ? 311 ALA B N   1 
ATOM   7930  C  CA  . ALA C 2 365 ? 158.343 142.730 176.762 1.00 108.98 ? 311 ALA B CA  1 
ATOM   7931  C  C   . ALA C 2 365 ? 158.763 142.856 175.305 1.00 106.65 ? 311 ALA B C   1 
ATOM   7932  O  O   . ALA C 2 365 ? 158.244 143.706 174.571 1.00 104.83 ? 311 ALA B O   1 
ATOM   7933  C  CB  . ALA C 2 365 ? 159.373 143.389 177.677 1.00 104.10 ? 311 ALA B CB  1 
ATOM   7934  N  N   . ARG C 2 366 ? 159.695 142.011 174.863 1.00 105.61 ? 312 ARG B N   1 
ATOM   7935  C  CA  . ARG C 2 366 ? 160.093 142.031 173.462 1.00 106.59 ? 312 ARG B CA  1 
ATOM   7936  C  C   . ARG C 2 366 ? 158.956 141.584 172.555 1.00 106.07 ? 312 ARG B C   1 
ATOM   7937  O  O   . ARG C 2 366 ? 158.841 142.076 171.433 1.00 106.17 ? 312 ARG B O   1 
ATOM   7938  C  CB  . ARG C 2 366 ? 161.326 141.156 173.246 1.00 109.77 ? 312 ARG B CB  1 
ATOM   7939  C  CG  . ARG C 2 366 ? 161.907 141.233 171.843 1.00 110.40 ? 312 ARG B CG  1 
ATOM   7940  C  CD  . ARG C 2 366 ? 163.153 140.373 171.712 1.00 112.12 ? 312 ARG B CD  1 
ATOM   7941  N  NE  . ARG C 2 366 ? 163.670 140.370 170.349 1.00 115.07 ? 312 ARG B NE  1 
ATOM   7942  C  CZ  . ARG C 2 366 ? 164.713 139.660 169.943 1.00 119.14 ? 312 ARG B CZ  1 
ATOM   7943  N  NH1 . ARG C 2 366 ? 165.384 138.881 170.775 1.00 116.61 ? 312 ARG B NH1 1 
ATOM   7944  N  NH2 . ARG C 2 366 ? 165.090 139.731 168.670 1.00 119.28 ? 312 ARG B NH2 1 
ATOM   7945  N  N   . ALA C 2 367 ? 158.104 140.668 173.019 1.00 106.45 ? 313 ALA B N   1 
ATOM   7946  C  CA  . ALA C 2 367 ? 156.942 140.283 172.224 1.00 102.20 ? 313 ALA B CA  1 
ATOM   7947  C  C   . ALA C 2 367 ? 155.982 141.453 172.046 1.00 100.98 ? 313 ALA B C   1 
ATOM   7948  O  O   . ALA C 2 367 ? 155.471 141.689 170.941 1.00 100.92 ? 313 ALA B O   1 
ATOM   7949  C  CB  . ALA C 2 367 ? 156.230 139.100 172.876 1.00 100.63 ? 313 ALA B CB  1 
ATOM   7950  N  N   . ALA C 2 368 ? 155.720 142.197 173.122 1.00 100.51 ? 314 ALA B N   1 
ATOM   7951  C  CA  . ALA C 2 368 ? 154.853 143.364 173.007 1.00 99.96  ? 314 ALA B CA  1 
ATOM   7952  C  C   . ALA C 2 368 ? 155.472 144.416 172.096 1.00 100.12 ? 314 ALA B C   1 
ATOM   7953  O  O   . ALA C 2 368 ? 154.773 145.045 171.292 1.00 98.56  ? 314 ALA B O   1 
ATOM   7954  C  CB  . ALA C 2 368 ? 154.567 143.946 174.389 1.00 101.95 ? 314 ALA B CB  1 
ATOM   7955  N  N   . ALA C 2 369 ? 156.787 144.615 172.206 1.00 99.53  ? 422 ALA B N   1 
ATOM   7956  C  CA  . ALA C 2 369 ? 157.471 145.546 171.316 1.00 98.16  ? 422 ALA B CA  1 
ATOM   7957  C  C   . ALA C 2 369 ? 157.374 145.094 169.865 1.00 97.13  ? 422 ALA B C   1 
ATOM   7958  O  O   . ALA C 2 369 ? 157.215 145.919 168.960 1.00 98.65  ? 422 ALA B O   1 
ATOM   7959  C  CB  . ALA C 2 369 ? 158.933 145.691 171.734 1.00 95.98  ? 422 ALA B CB  1 
ATOM   7960  N  N   . ILE C 2 370 ? 157.475 143.788 169.625 1.00 95.77  ? 423 ILE B N   1 
ATOM   7961  C  CA  . ILE C 2 370 ? 157.381 143.264 168.268 1.00 94.01  ? 423 ILE B CA  1 
ATOM   7962  C  C   . ILE C 2 370 ? 155.993 143.504 167.695 1.00 90.99  ? 423 ILE B C   1 
ATOM   7963  O  O   . ILE C 2 370 ? 155.850 143.927 166.542 1.00 91.37  ? 423 ILE B O   1 
ATOM   7964  C  CB  . ILE C 2 370 ? 157.763 141.775 168.252 1.00 93.41  ? 423 ILE B CB  1 
ATOM   7965  C  CG1 . ILE C 2 370 ? 159.283 141.633 168.308 1.00 95.47  ? 423 ILE B CG1 1 
ATOM   7966  C  CG2 . ILE C 2 370 ? 157.199 141.087 167.028 1.00 87.95  ? 423 ILE B CG2 1 
ATOM   7967  C  CD1 . ILE C 2 370 ? 159.771 140.215 168.227 1.00 97.75  ? 423 ILE B CD1 1 
ATOM   7968  N  N   . ASP C 2 371 ? 154.950 143.256 168.488 1.00 91.00  ? 424 ASP B N   1 
ATOM   7969  C  CA  . ASP C 2 371 ? 153.597 143.553 168.024 1.00 91.91  ? 424 ASP B CA  1 
ATOM   7970  C  C   . ASP C 2 371 ? 153.433 145.039 167.725 1.00 91.41  ? 424 ASP B C   1 
ATOM   7971  O  O   . ASP C 2 371 ? 152.883 145.421 166.682 1.00 89.51  ? 424 ASP B O   1 
ATOM   7972  C  CB  . ASP C 2 371 ? 152.569 143.104 169.058 1.00 93.90  ? 424 ASP B CB  1 
ATOM   7973  C  CG  . ASP C 2 371 ? 152.196 141.647 168.914 1.00 95.75  ? 424 ASP B CG  1 
ATOM   7974  O  OD1 . ASP C 2 371 ? 153.035 140.785 169.241 1.00 97.15  ? 424 ASP B OD1 1 
ATOM   7975  O  OD2 . ASP C 2 371 ? 151.062 141.362 168.478 1.00 94.24  ? 424 ASP B OD2 1 
ATOM   7976  N  N   . ARG C 2 372 ? 153.913 145.894 168.630 1.00 92.40  ? 425 ARG B N   1 
ATOM   7977  C  CA  . ARG C 2 372 ? 153.733 147.331 168.458 1.00 93.33  ? 425 ARG B CA  1 
ATOM   7978  C  C   . ARG C 2 372 ? 154.471 147.837 167.226 1.00 92.10  ? 425 ARG B C   1 
ATOM   7979  O  O   . ARG C 2 372 ? 153.980 148.726 166.521 1.00 89.84  ? 425 ARG B O   1 
ATOM   7980  C  CB  . ARG C 2 372 ? 154.200 148.072 169.709 1.00 97.43  ? 425 ARG B CB  1 
ATOM   7981  C  CG  . ARG C 2 372 ? 153.735 149.518 169.775 1.00 102.54 ? 425 ARG B CG  1 
ATOM   7982  C  CD  . ARG C 2 372 ? 154.062 150.165 171.111 1.00 105.42 ? 425 ARG B CD  1 
ATOM   7983  N  NE  . ARG C 2 372 ? 153.753 149.290 172.234 1.00 112.01 ? 425 ARG B NE  1 
ATOM   7984  C  CZ  . ARG C 2 372 ? 154.664 148.686 172.986 1.00 111.88 ? 425 ARG B CZ  1 
ATOM   7985  N  NH1 . ARG C 2 372 ? 155.959 148.863 172.779 1.00 107.00 ? 425 ARG B NH1 1 
ATOM   7986  N  NH2 . ARG C 2 372 ? 154.265 147.883 173.968 1.00 109.20 ? 425 ARG B NH2 1 
ATOM   7987  N  N   . TRP C 2 373 ? 155.659 147.299 166.959 1.00 91.57  ? 426 TRP B N   1 
ATOM   7988  C  CA  . TRP C 2 373 ? 156.390 147.700 165.763 1.00 90.47  ? 426 TRP B CA  1 
ATOM   7989  C  C   . TRP C 2 373 ? 155.732 147.158 164.502 1.00 89.16  ? 426 TRP B C   1 
ATOM   7990  O  O   . TRP C 2 373 ? 155.723 147.834 163.468 1.00 88.18  ? 426 TRP B O   1 
ATOM   7991  C  CB  . TRP C 2 373 ? 157.845 147.252 165.860 1.00 90.67  ? 426 TRP B CB  1 
ATOM   7992  C  CG  . TRP C 2 373 ? 158.705 148.229 166.595 1.00 98.08  ? 426 TRP B CG  1 
ATOM   7993  C  CD1 . TRP C 2 373 ? 158.700 148.478 167.936 1.00 101.24 ? 426 TRP B CD1 1 
ATOM   7994  C  CD2 . TRP C 2 373 ? 159.697 149.093 166.031 1.00 103.12 ? 426 TRP B CD2 1 
ATOM   7995  N  NE1 . TRP C 2 373 ? 159.626 149.443 168.242 1.00 104.31 ? 426 TRP B NE1 1 
ATOM   7996  C  CE2 . TRP C 2 373 ? 160.253 149.837 167.089 1.00 104.60 ? 426 TRP B CE2 1 
ATOM   7997  C  CE3 . TRP C 2 373 ? 160.169 149.311 164.734 1.00 103.03 ? 426 TRP B CE3 1 
ATOM   7998  C  CZ2 . TRP C 2 373 ? 161.257 150.781 166.891 1.00 104.41 ? 426 TRP B CZ2 1 
ATOM   7999  C  CZ3 . TRP C 2 373 ? 161.165 150.248 164.539 1.00 105.19 ? 426 TRP B CZ3 1 
ATOM   8000  C  CH2 . TRP C 2 373 ? 161.699 150.972 165.612 1.00 105.24 ? 426 TRP B CH2 1 
ATOM   8001  N  N   . SER C 2 374 ? 155.172 145.946 164.564 1.00 87.90  ? 427 SER B N   1 
ATOM   8002  C  CA  . SER C 2 374 ? 154.458 145.410 163.409 1.00 80.54  ? 427 SER B CA  1 
ATOM   8003  C  C   . SER C 2 374 ? 153.260 146.276 163.057 1.00 79.04  ? 427 SER B C   1 
ATOM   8004  O  O   . SER C 2 374 ? 152.955 146.469 161.872 1.00 77.39  ? 427 SER B O   1 
ATOM   8005  C  CB  . SER C 2 374 ? 154.014 143.976 163.675 1.00 76.78  ? 427 SER B CB  1 
ATOM   8006  O  OG  . SER C 2 374 ? 155.119 143.098 163.659 1.00 81.13  ? 427 SER B OG  1 
ATOM   8007  N  N   . ARG C 2 375 ? 152.596 146.835 164.075 1.00 81.31  ? 428 ARG B N   1 
ATOM   8008  C  CA  . ARG C 2 375 ? 151.413 147.660 163.839 1.00 80.64  ? 428 ARG B CA  1 
ATOM   8009  C  C   . ARG C 2 375 ? 151.693 148.791 162.864 1.00 77.99  ? 428 ARG B C   1 
ATOM   8010  O  O   . ARG C 2 375 ? 150.787 149.235 162.152 1.00 78.19  ? 428 ARG B O   1 
ATOM   8011  C  CB  . ARG C 2 375 ? 150.902 148.249 165.153 1.00 82.39  ? 428 ARG B CB  1 
ATOM   8012  C  CG  . ARG C 2 375 ? 150.478 147.231 166.185 1.00 85.41  ? 428 ARG B CG  1 
ATOM   8013  C  CD  . ARG C 2 375 ? 150.057 147.916 167.464 1.00 87.11  ? 428 ARG B CD  1 
ATOM   8014  N  NE  . ARG C 2 375 ? 149.959 146.993 168.585 1.00 88.43  ? 428 ARG B NE  1 
ATOM   8015  C  CZ  . ARG C 2 375 ? 149.526 147.335 169.790 1.00 91.24  ? 428 ARG B CZ  1 
ATOM   8016  N  NH1 . ARG C 2 375 ? 149.132 148.570 170.056 1.00 90.45  ? 428 ARG B NH1 1 
ATOM   8017  N  NH2 . ARG C 2 375 ? 149.483 146.417 170.750 1.00 94.20  ? 428 ARG B NH2 1 
ATOM   8018  N  N   . ILE C 2 376 ? 152.928 149.279 162.826 1.00 79.27  ? 429 ILE B N   1 
ATOM   8019  C  CA  . ILE C 2 376 ? 153.325 150.323 161.895 1.00 80.05  ? 429 ILE B CA  1 
ATOM   8020  C  C   . ILE C 2 376 ? 154.006 149.747 160.662 1.00 78.89  ? 429 ILE B C   1 
ATOM   8021  O  O   . ILE C 2 376 ? 153.756 150.200 159.546 1.00 80.18  ? 429 ILE B O   1 
ATOM   8022  C  CB  . ILE C 2 376 ? 154.233 151.349 162.606 1.00 80.89  ? 429 ILE B CB  1 
ATOM   8023  C  CG1 . ILE C 2 376 ? 153.448 152.083 163.692 1.00 84.01  ? 429 ILE B CG1 1 
ATOM   8024  C  CG2 . ILE C 2 376 ? 154.820 152.336 161.609 1.00 78.71  ? 429 ILE B CG2 1 
ATOM   8025  C  CD1 . ILE C 2 376 ? 154.308 152.940 164.594 1.00 88.24  ? 429 ILE B CD1 1 
ATOM   8026  N  N   . VAL C 2 377 ? 154.855 148.733 160.845 1.00 77.59  ? 430 VAL B N   1 
ATOM   8027  C  CA  . VAL C 2 377 ? 155.651 148.218 159.734 1.00 75.28  ? 430 VAL B CA  1 
ATOM   8028  C  C   . VAL C 2 377 ? 154.759 147.625 158.653 1.00 74.47  ? 430 VAL B C   1 
ATOM   8029  O  O   . VAL C 2 377 ? 154.968 147.873 157.459 1.00 73.95  ? 430 VAL B O   1 
ATOM   8030  C  CB  . VAL C 2 377 ? 156.679 147.192 160.240 1.00 72.89  ? 430 VAL B CB  1 
ATOM   8031  C  CG1 . VAL C 2 377 ? 157.305 146.454 159.076 1.00 69.61  ? 430 VAL B CG1 1 
ATOM   8032  C  CG2 . VAL C 2 377 ? 157.746 147.884 161.056 1.00 72.63  ? 430 VAL B CG2 1 
ATOM   8033  N  N   . PHE C 2 378 ? 153.755 146.836 159.040 1.00 71.94  ? 431 PHE B N   1 
ATOM   8034  C  CA  . PHE C 2 378 ? 152.941 146.164 158.029 1.00 66.73  ? 431 PHE B CA  1 
ATOM   8035  C  C   . PHE C 2 378 ? 152.209 147.137 157.112 1.00 70.21  ? 431 PHE B C   1 
ATOM   8036  O  O   . PHE C 2 378 ? 152.336 147.000 155.882 1.00 72.52  ? 431 PHE B O   1 
ATOM   8037  C  CB  . PHE C 2 378 ? 151.982 145.181 158.706 1.00 66.73  ? 431 PHE B CB  1 
ATOM   8038  C  CG  . PHE C 2 378 ? 152.517 143.785 158.800 1.00 71.17  ? 431 PHE B CG  1 
ATOM   8039  C  CD1 . PHE C 2 378 ? 153.514 143.470 159.701 1.00 72.67  ? 431 PHE B CD1 1 
ATOM   8040  C  CD2 . PHE C 2 378 ? 152.021 142.785 157.989 1.00 68.61  ? 431 PHE B CD2 1 
ATOM   8041  C  CE1 . PHE C 2 378 ? 154.004 142.188 159.787 1.00 69.59  ? 431 PHE B CE1 1 
ATOM   8042  C  CE2 . PHE C 2 378 ? 152.510 141.501 158.074 1.00 66.14  ? 431 PHE B CE2 1 
ATOM   8043  C  CZ  . PHE C 2 378 ? 153.500 141.204 158.972 1.00 64.31  ? 431 PHE B CZ  1 
ATOM   8044  N  N   . PRO C 2 379 ? 151.455 148.126 157.607 1.00 71.45  ? 432 PRO B N   1 
ATOM   8045  C  CA  . PRO C 2 379 ? 150.861 149.101 156.680 1.00 70.64  ? 432 PRO B CA  1 
ATOM   8046  C  C   . PRO C 2 379 ? 151.888 149.889 155.890 1.00 72.40  ? 432 PRO B C   1 
ATOM   8047  O  O   . PRO C 2 379 ? 151.635 150.217 154.726 1.00 73.74  ? 432 PRO B O   1 
ATOM   8048  C  CB  . PRO C 2 379 ? 150.040 150.006 157.606 1.00 67.86  ? 432 PRO B CB  1 
ATOM   8049  C  CG  . PRO C 2 379 ? 149.743 149.157 158.780 1.00 68.26  ? 432 PRO B CG  1 
ATOM   8050  C  CD  . PRO C 2 379 ? 150.989 148.359 158.984 1.00 71.82  ? 432 PRO B CD  1 
ATOM   8051  N  N   . PHE C 2 380 ? 153.047 150.190 156.474 1.00 71.23  ? 433 PHE B N   1 
ATOM   8052  C  CA  . PHE C 2 380 ? 154.073 150.928 155.744 1.00 72.91  ? 433 PHE B CA  1 
ATOM   8053  C  C   . PHE C 2 380 ? 154.612 150.117 154.570 1.00 74.43  ? 433 PHE B C   1 
ATOM   8054  O  O   . PHE C 2 380 ? 154.718 150.626 153.447 1.00 74.16  ? 433 PHE B O   1 
ATOM   8055  C  CB  . PHE C 2 380 ? 155.202 151.321 156.694 1.00 77.00  ? 433 PHE B CB  1 
ATOM   8056  C  CG  . PHE C 2 380 ? 156.351 152.004 156.020 1.00 81.16  ? 433 PHE B CG  1 
ATOM   8057  C  CD1 . PHE C 2 380 ? 156.244 153.316 155.604 1.00 79.66  ? 433 PHE B CD1 1 
ATOM   8058  C  CD2 . PHE C 2 380 ? 157.543 151.335 155.809 1.00 81.37  ? 433 PHE B CD2 1 
ATOM   8059  C  CE1 . PHE C 2 380 ? 157.301 153.947 154.985 1.00 79.41  ? 433 PHE B CE1 1 
ATOM   8060  C  CE2 . PHE C 2 380 ? 158.603 151.962 155.190 1.00 82.08  ? 433 PHE B CE2 1 
ATOM   8061  C  CZ  . PHE C 2 380 ? 158.482 153.269 154.780 1.00 80.38  ? 433 PHE B CZ  1 
ATOM   8062  N  N   . THR C 2 381 ? 154.950 148.847 154.803 1.00 73.23  ? 434 THR B N   1 
ATOM   8063  C  CA  . THR C 2 381 ? 155.454 148.021 153.711 1.00 71.06  ? 434 THR B CA  1 
ATOM   8064  C  C   . THR C 2 381 ? 154.375 147.733 152.677 1.00 69.93  ? 434 THR B C   1 
ATOM   8065  O  O   . THR C 2 381 ? 154.680 147.630 151.486 1.00 73.54  ? 434 THR B O   1 
ATOM   8066  C  CB  . THR C 2 381 ? 156.033 146.710 154.240 1.00 71.44  ? 434 THR B CB  1 
ATOM   8067  O  OG1 . THR C 2 381 ? 155.040 146.021 155.006 1.00 76.25  ? 434 THR B OG1 1 
ATOM   8068  C  CG2 . THR C 2 381 ? 157.249 146.979 155.105 1.00 71.47  ? 434 THR B CG2 1 
ATOM   8069  N  N   . PHE C 2 382 ? 153.119 147.591 153.100 1.00 67.81  ? 435 PHE B N   1 
ATOM   8070  C  CA  . PHE C 2 382 ? 152.054 147.392 152.124 1.00 64.92  ? 435 PHE B CA  1 
ATOM   8071  C  C   . PHE C 2 382 ? 151.842 148.634 151.271 1.00 65.99  ? 435 PHE B C   1 
ATOM   8072  O  O   . PHE C 2 382 ? 151.608 148.532 150.061 1.00 67.63  ? 435 PHE B O   1 
ATOM   8073  C  CB  . PHE C 2 382 ? 150.763 147.004 152.827 1.00 63.98  ? 435 PHE B CB  1 
ATOM   8074  C  CG  . PHE C 2 382 ? 149.655 146.629 151.894 1.00 63.89  ? 435 PHE B CG  1 
ATOM   8075  C  CD1 . PHE C 2 382 ? 149.675 145.419 151.231 1.00 64.59  ? 435 PHE B CD1 1 
ATOM   8076  C  CD2 . PHE C 2 382 ? 148.585 147.476 151.692 1.00 62.56  ? 435 PHE B CD2 1 
ATOM   8077  C  CE1 . PHE C 2 382 ? 148.659 145.068 150.378 1.00 65.95  ? 435 PHE B CE1 1 
ATOM   8078  C  CE2 . PHE C 2 382 ? 147.562 147.124 150.844 1.00 62.89  ? 435 PHE B CE2 1 
ATOM   8079  C  CZ  . PHE C 2 382 ? 147.600 145.920 150.186 1.00 64.69  ? 435 PHE B CZ  1 
ATOM   8080  N  N   . SER C 2 383 ? 151.911 149.817 151.880 1.00 67.19  ? 436 SER B N   1 
ATOM   8081  C  CA  . SER C 2 383 ? 151.824 151.043 151.100 1.00 67.12  ? 436 SER B CA  1 
ATOM   8082  C  C   . SER C 2 383 ? 152.992 151.148 150.134 1.00 68.30  ? 436 SER B C   1 
ATOM   8083  O  O   . SER C 2 383 ? 152.828 151.598 148.997 1.00 69.15  ? 436 SER B O   1 
ATOM   8084  C  CB  . SER C 2 383 ? 151.777 152.254 152.026 1.00 70.49  ? 436 SER B CB  1 
ATOM   8085  O  OG  . SER C 2 383 ? 150.679 152.169 152.914 1.00 71.80  ? 436 SER B OG  1 
ATOM   8086  N  N   . LEU C 2 384 ? 154.180 150.729 150.569 1.00 69.98  ? 437 LEU B N   1 
ATOM   8087  C  CA  . LEU C 2 384 ? 155.336 150.741 149.680 1.00 72.02  ? 437 LEU B CA  1 
ATOM   8088  C  C   . LEU C 2 384 ? 155.137 149.800 148.499 1.00 68.17  ? 437 LEU B C   1 
ATOM   8089  O  O   . LEU C 2 384 ? 155.444 150.151 147.354 1.00 67.88  ? 437 LEU B O   1 
ATOM   8090  C  CB  . LEU C 2 384 ? 156.591 150.363 150.460 1.00 74.27  ? 437 LEU B CB  1 
ATOM   8091  C  CG  . LEU C 2 384 ? 157.850 151.105 150.035 1.00 76.67  ? 437 LEU B CG  1 
ATOM   8092  C  CD1 . LEU C 2 384 ? 157.578 152.598 150.044 1.00 73.58  ? 437 LEU B CD1 1 
ATOM   8093  C  CD2 . LEU C 2 384 ? 158.996 150.761 150.960 1.00 73.74  ? 437 LEU B CD2 1 
ATOM   8094  N  N   . PHE C 2 385 ? 154.631 148.596 148.763 1.00 67.60  ? 438 PHE B N   1 
ATOM   8095  C  CA  . PHE C 2 385 ? 154.376 147.636 147.694 1.00 65.84  ? 438 PHE B CA  1 
ATOM   8096  C  C   . PHE C 2 385 ? 153.349 148.173 146.707 1.00 66.33  ? 438 PHE B C   1 
ATOM   8097  O  O   . PHE C 2 385 ? 153.534 148.073 145.488 1.00 66.54  ? 438 PHE B O   1 
ATOM   8098  C  CB  . PHE C 2 385 ? 153.916 146.310 148.301 1.00 63.01  ? 438 PHE B CB  1 
ATOM   8099  C  CG  . PHE C 2 385 ? 153.249 145.387 147.327 1.00 66.75  ? 438 PHE B CG  1 
ATOM   8100  C  CD1 . PHE C 2 385 ? 153.995 144.622 146.454 1.00 64.60  ? 438 PHE B CD1 1 
ATOM   8101  C  CD2 . PHE C 2 385 ? 151.873 145.265 147.303 1.00 66.27  ? 438 PHE B CD2 1 
ATOM   8102  C  CE1 . PHE C 2 385 ? 153.377 143.770 145.569 1.00 61.26  ? 438 PHE B CE1 1 
ATOM   8103  C  CE2 . PHE C 2 385 ? 151.256 144.415 146.416 1.00 60.46  ? 438 PHE B CE2 1 
ATOM   8104  C  CZ  . PHE C 2 385 ? 152.007 143.669 145.552 1.00 58.57  ? 438 PHE B CZ  1 
ATOM   8105  N  N   . ASN C 2 386 ? 152.266 148.761 147.216 1.00 65.38  ? 439 ASN B N   1 
ATOM   8106  C  CA  . ASN C 2 386 ? 151.259 149.336 146.333 1.00 64.73  ? 439 ASN B CA  1 
ATOM   8107  C  C   . ASN C 2 386 ? 151.832 150.482 145.514 1.00 67.43  ? 439 ASN B C   1 
ATOM   8108  O  O   . ASN C 2 386 ? 151.521 150.617 144.327 1.00 71.22  ? 439 ASN B O   1 
ATOM   8109  C  CB  . ASN C 2 386 ? 150.054 149.806 147.142 1.00 67.63  ? 439 ASN B CB  1 
ATOM   8110  C  CG  . ASN C 2 386 ? 149.110 148.680 147.476 1.00 70.18  ? 439 ASN B CG  1 
ATOM   8111  O  OD1 . ASN C 2 386 ? 148.026 148.574 146.907 1.00 69.73  ? 439 ASN B OD1 1 
ATOM   8112  N  ND2 . ASN C 2 386 ? 149.522 147.818 148.391 1.00 70.87  ? 439 ASN B ND2 1 
ATOM   8113  N  N   . LEU C 2 387 ? 152.657 151.328 146.131 1.00 69.07  ? 440 LEU B N   1 
ATOM   8114  C  CA  . LEU C 2 387 ? 153.252 152.444 145.404 1.00 69.28  ? 440 LEU B CA  1 
ATOM   8115  C  C   . LEU C 2 387 ? 154.148 151.948 144.278 1.00 68.42  ? 440 LEU B C   1 
ATOM   8116  O  O   . LEU C 2 387 ? 154.073 152.439 143.147 1.00 71.14  ? 440 LEU B O   1 
ATOM   8117  C  CB  . LEU C 2 387 ? 154.042 153.329 146.365 1.00 71.89  ? 440 LEU B CB  1 
ATOM   8118  C  CG  . LEU C 2 387 ? 154.695 154.571 145.766 1.00 74.22  ? 440 LEU B CG  1 
ATOM   8119  C  CD1 . LEU C 2 387 ? 153.757 155.761 145.869 1.00 76.96  ? 440 LEU B CD1 1 
ATOM   8120  C  CD2 . LEU C 2 387 ? 156.025 154.861 146.437 1.00 72.42  ? 440 LEU B CD2 1 
ATOM   8121  N  N   . VAL C 2 388 ? 154.994 150.958 144.570 1.00 65.55  ? 441 VAL B N   1 
ATOM   8122  C  CA  . VAL C 2 388 ? 155.867 150.400 143.541 1.00 63.96  ? 441 VAL B CA  1 
ATOM   8123  C  C   . VAL C 2 388 ? 155.040 149.802 142.413 1.00 67.63  ? 441 VAL B C   1 
ATOM   8124  O  O   . VAL C 2 388 ? 155.337 150.003 141.229 1.00 69.33  ? 441 VAL B O   1 
ATOM   8125  C  CB  . VAL C 2 388 ? 156.819 149.357 144.154 1.00 59.57  ? 441 VAL B CB  1 
ATOM   8126  C  CG1 . VAL C 2 388 ? 157.577 148.632 143.068 1.00 57.18  ? 441 VAL B CG1 1 
ATOM   8127  C  CG2 . VAL C 2 388 ? 157.783 150.020 145.111 1.00 60.53  ? 441 VAL B CG2 1 
ATOM   8128  N  N   . TYR C 2 389 ? 153.980 149.071 142.762 1.00 67.62  ? 442 TYR B N   1 
ATOM   8129  C  CA  . TYR C 2 389 ? 153.127 148.454 141.753 1.00 63.95  ? 442 TYR B CA  1 
ATOM   8130  C  C   . TYR C 2 389 ? 152.472 149.503 140.861 1.00 68.14  ? 442 TYR B C   1 
ATOM   8131  O  O   . TYR C 2 389 ? 152.545 149.421 139.630 1.00 72.52  ? 442 TYR B O   1 
ATOM   8132  C  CB  . TYR C 2 389 ? 152.073 147.592 142.447 1.00 63.90  ? 442 TYR B CB  1 
ATOM   8133  C  CG  . TYR C 2 389 ? 151.081 146.924 141.531 1.00 61.48  ? 442 TYR B CG  1 
ATOM   8134  C  CD1 . TYR C 2 389 ? 151.339 145.677 140.990 1.00 60.47  ? 442 TYR B CD1 1 
ATOM   8135  C  CD2 . TYR C 2 389 ? 149.873 147.529 141.232 1.00 64.08  ? 442 TYR B CD2 1 
ATOM   8136  C  CE1 . TYR C 2 389 ? 150.432 145.062 140.161 1.00 59.74  ? 442 TYR B CE1 1 
ATOM   8137  C  CE2 . TYR C 2 389 ? 148.959 146.919 140.405 1.00 65.28  ? 442 TYR B CE2 1 
ATOM   8138  C  CZ  . TYR C 2 389 ? 149.243 145.686 139.875 1.00 62.04  ? 442 TYR B CZ  1 
ATOM   8139  O  OH  . TYR C 2 389 ? 148.330 145.078 139.049 1.00 62.03  ? 442 TYR B OH  1 
ATOM   8140  N  N   . TRP C 2 390 ? 151.831 150.503 141.464 1.00 68.56  ? 443 TRP B N   1 
ATOM   8141  C  CA  . TRP C 2 390 ? 151.103 151.504 140.696 1.00 68.64  ? 443 TRP B CA  1 
ATOM   8142  C  C   . TRP C 2 390 ? 152.015 152.505 140.008 1.00 71.57  ? 443 TRP B C   1 
ATOM   8143  O  O   . TRP C 2 390 ? 151.528 153.297 139.197 1.00 76.34  ? 443 TRP B O   1 
ATOM   8144  C  CB  . TRP C 2 390 ? 150.106 152.249 141.588 1.00 69.84  ? 443 TRP B CB  1 
ATOM   8145  C  CG  . TRP C 2 390 ? 148.991 151.379 142.105 1.00 76.26  ? 443 TRP B CG  1 
ATOM   8146  C  CD1 . TRP C 2 390 ? 148.771 151.013 143.399 1.00 74.93  ? 443 TRP B CD1 1 
ATOM   8147  C  CD2 . TRP C 2 390 ? 147.952 150.762 141.334 1.00 78.72  ? 443 TRP B CD2 1 
ATOM   8148  N  NE1 . TRP C 2 390 ? 147.662 150.210 143.484 1.00 73.35  ? 443 TRP B NE1 1 
ATOM   8149  C  CE2 . TRP C 2 390 ? 147.141 150.041 142.230 1.00 76.67  ? 443 TRP B CE2 1 
ATOM   8150  C  CE3 . TRP C 2 390 ? 147.630 150.749 139.974 1.00 79.98  ? 443 TRP B CE3 1 
ATOM   8151  C  CZ2 . TRP C 2 390 ? 146.030 149.318 141.812 1.00 76.21  ? 443 TRP B CZ2 1 
ATOM   8152  C  CZ3 . TRP C 2 390 ? 146.526 150.030 139.562 1.00 79.14  ? 443 TRP B CZ3 1 
ATOM   8153  C  CH2 . TRP C 2 390 ? 145.740 149.325 140.477 1.00 75.81  ? 443 TRP B CH2 1 
ATOM   8154  N  N   . LEU C 2 391 ? 153.308 152.510 140.316 1.00 73.86  ? 444 LEU B N   1 
ATOM   8155  C  CA  . LEU C 2 391 ? 154.243 153.272 139.500 1.00 76.04  ? 444 LEU B CA  1 
ATOM   8156  C  C   . LEU C 2 391 ? 154.832 152.450 138.364 1.00 75.26  ? 444 LEU B C   1 
ATOM   8157  O  O   . LEU C 2 391 ? 155.123 153.004 137.299 1.00 78.76  ? 444 LEU B O   1 
ATOM   8158  C  CB  . LEU C 2 391 ? 155.376 153.835 140.361 1.00 75.18  ? 444 LEU B CB  1 
ATOM   8159  C  CG  . LEU C 2 391 ? 154.984 154.957 141.324 1.00 77.34  ? 444 LEU B CG  1 
ATOM   8160  C  CD1 . LEU C 2 391 ? 156.219 155.557 141.964 1.00 76.40  ? 444 LEU B CD1 1 
ATOM   8161  C  CD2 . LEU C 2 391 ? 154.163 156.026 140.616 1.00 70.45  ? 444 LEU B CD2 1 
ATOM   8162  N  N   . TYR C 2 392 ? 155.026 151.146 138.560 1.00 74.98  ? 445 TYR B N   1 
ATOM   8163  C  CA  . TYR C 2 392 ? 155.586 150.329 137.490 1.00 77.26  ? 445 TYR B CA  1 
ATOM   8164  C  C   . TYR C 2 392 ? 154.550 149.994 136.423 1.00 75.15  ? 445 TYR B C   1 
ATOM   8165  O  O   . TYR C 2 392 ? 154.871 149.977 135.231 1.00 74.51  ? 445 TYR B O   1 
ATOM   8166  C  CB  . TYR C 2 392 ? 156.186 149.048 138.062 1.00 76.81  ? 445 TYR B CB  1 
ATOM   8167  C  CG  . TYR C 2 392 ? 156.611 148.050 137.013 1.00 81.61  ? 445 TYR B CG  1 
ATOM   8168  C  CD1 . TYR C 2 392 ? 157.802 148.205 136.323 1.00 86.14  ? 445 TYR B CD1 1 
ATOM   8169  C  CD2 . TYR C 2 392 ? 155.824 146.947 136.718 1.00 81.69  ? 445 TYR B CD2 1 
ATOM   8170  C  CE1 . TYR C 2 392 ? 158.197 147.291 135.364 1.00 92.69  ? 445 TYR B CE1 1 
ATOM   8171  C  CE2 . TYR C 2 392 ? 156.209 146.029 135.765 1.00 84.91  ? 445 TYR B CE2 1 
ATOM   8172  C  CZ  . TYR C 2 392 ? 157.396 146.204 135.089 1.00 92.03  ? 445 TYR B CZ  1 
ATOM   8173  O  OH  . TYR C 2 392 ? 157.780 145.288 134.136 1.00 90.64  ? 445 TYR B OH  1 
ATOM   8174  N  N   . TYR C 2 393 ? 153.311 149.725 136.822 1.00 74.60  ? 446 TYR B N   1 
ATOM   8175  C  CA  . TYR C 2 393 ? 152.280 149.312 135.883 1.00 74.85  ? 446 TYR B CA  1 
ATOM   8176  C  C   . TYR C 2 393 ? 151.359 150.450 135.468 1.00 75.51  ? 446 TYR B C   1 
ATOM   8177  O  O   . TYR C 2 393 ? 150.297 150.192 134.894 1.00 71.65  ? 446 TYR B O   1 
ATOM   8178  C  CB  . TYR C 2 393 ? 151.462 148.159 136.464 1.00 68.40  ? 446 TYR B CB  1 
ATOM   8179  C  CG  . TYR C 2 393 ? 152.101 146.809 136.243 1.00 72.67  ? 446 TYR B CG  1 
ATOM   8180  C  CD1 . TYR C 2 393 ? 152.280 146.312 134.964 1.00 72.81  ? 446 TYR B CD1 1 
ATOM   8181  C  CD2 . TYR C 2 393 ? 152.519 146.030 137.311 1.00 76.06  ? 446 TYR B CD2 1 
ATOM   8182  C  CE1 . TYR C 2 393 ? 152.860 145.085 134.753 1.00 73.80  ? 446 TYR B CE1 1 
ATOM   8183  C  CE2 . TYR C 2 393 ? 153.101 144.796 137.108 1.00 74.17  ? 446 TYR B CE2 1 
ATOM   8184  C  CZ  . TYR C 2 393 ? 153.268 144.330 135.826 1.00 78.65  ? 446 TYR B CZ  1 
ATOM   8185  O  OH  . TYR C 2 393 ? 153.844 143.102 135.607 1.00 79.67  ? 446 TYR B OH  1 
ATOM   8186  N  N   . VAL C 2 394 ? 151.726 151.693 135.755 1.00 76.93  ? 447 VAL B N   1 
ATOM   8187  C  CA  . VAL C 2 394 ? 150.988 152.846 135.251 1.00 79.19  ? 447 VAL B CA  1 
ATOM   8188  C  C   . VAL C 2 394 ? 151.965 153.924 134.796 1.00 79.64  ? 447 VAL B C   1 
ATOM   8189  O  O   . VAL C 2 394 ? 152.686 153.750 133.815 1.00 80.14  ? 447 VAL B O   1 
ATOM   8190  C  CB  . VAL C 2 394 ? 150.020 153.412 136.299 1.00 77.68  ? 447 VAL B CB  1 
ATOM   8191  C  CG1 . VAL C 2 394 ? 149.501 154.768 135.847 1.00 73.51  ? 447 VAL B CG1 1 
ATOM   8192  C  CG2 . VAL C 2 394 ? 148.865 152.459 136.535 1.00 67.69  ? 447 VAL B CG2 1 
ATOM   8193  N  N   . THR D 1 65  ? 150.512 143.992 73.612  1.00 85.42  ? 12  THR A N   1 
ATOM   8194  C  CA  . THR D 1 65  ? 149.777 143.103 74.501  1.00 91.34  ? 12  THR A CA  1 
ATOM   8195  C  C   . THR D 1 65  ? 149.270 141.879 73.741  1.00 90.72  ? 12  THR A C   1 
ATOM   8196  O  O   . THR D 1 65  ? 149.224 140.777 74.282  1.00 88.47  ? 12  THR A O   1 
ATOM   8197  C  CB  . THR D 1 65  ? 148.592 143.831 75.165  1.00 93.19  ? 12  THR A CB  1 
ATOM   8198  O  OG1 . THR D 1 65  ? 149.071 144.997 75.845  1.00 99.65  ? 12  THR A OG1 1 
ATOM   8199  C  CG2 . THR D 1 65  ? 147.893 142.934 76.169  1.00 87.54  ? 12  THR A CG2 1 
ATOM   8200  N  N   . THR D 1 66  ? 148.901 142.080 72.475  1.00 89.28  ? 13  THR A N   1 
ATOM   8201  C  CA  . THR D 1 66  ? 148.401 140.981 71.658  1.00 84.89  ? 13  THR A CA  1 
ATOM   8202  C  C   . THR D 1 66  ? 149.455 139.905 71.431  1.00 83.01  ? 13  THR A C   1 
ATOM   8203  O  O   . THR D 1 66  ? 149.103 138.750 71.163  1.00 84.14  ? 13  THR A O   1 
ATOM   8204  C  CB  . THR D 1 66  ? 147.899 141.517 70.318  1.00 86.78  ? 13  THR A CB  1 
ATOM   8205  O  OG1 . THR D 1 66  ? 147.169 142.730 70.538  1.00 93.22  ? 13  THR A OG1 1 
ATOM   8206  C  CG2 . THR D 1 66  ? 146.987 140.509 69.646  1.00 83.57  ? 13  THR A CG2 1 
ATOM   8207  N  N   . VAL D 1 67  ? 150.738 140.255 71.532  1.00 82.54  ? 14  VAL A N   1 
ATOM   8208  C  CA  . VAL D 1 67  ? 151.789 139.249 71.422  1.00 82.63  ? 14  VAL A CA  1 
ATOM   8209  C  C   . VAL D 1 67  ? 151.662 138.231 72.543  1.00 79.60  ? 14  VAL A C   1 
ATOM   8210  O  O   . VAL D 1 67  ? 151.769 137.018 72.323  1.00 78.78  ? 14  VAL A O   1 
ATOM   8211  C  CB  . VAL D 1 67  ? 153.174 139.921 71.428  1.00 80.54  ? 14  VAL A CB  1 
ATOM   8212  C  CG1 . VAL D 1 67  ? 154.259 138.896 71.148  1.00 77.74  ? 14  VAL A CG1 1 
ATOM   8213  C  CG2 . VAL D 1 67  ? 153.218 141.048 70.417  1.00 76.88  ? 14  VAL A CG2 1 
ATOM   8214  N  N   . PHE D 1 68  ? 151.431 138.707 73.763  1.00 77.93  ? 15  PHE A N   1 
ATOM   8215  C  CA  . PHE D 1 68  ? 151.301 137.798 74.892  1.00 74.55  ? 15  PHE A CA  1 
ATOM   8216  C  C   . PHE D 1 68  ? 150.016 136.987 74.814  1.00 69.60  ? 15  PHE A C   1 
ATOM   8217  O  O   . PHE D 1 68  ? 149.995 135.823 75.228  1.00 69.04  ? 15  PHE A O   1 
ATOM   8218  C  CB  . PHE D 1 68  ? 151.387 138.589 76.190  1.00 79.07  ? 15  PHE A CB  1 
ATOM   8219  C  CG  . PHE D 1 68  ? 152.645 139.396 76.311  1.00 81.06  ? 15  PHE A CG  1 
ATOM   8220  C  CD1 . PHE D 1 68  ? 153.824 138.805 76.719  1.00 80.06  ? 15  PHE A CD1 1 
ATOM   8221  C  CD2 . PHE D 1 68  ? 152.652 140.740 76.000  1.00 83.52  ? 15  PHE A CD2 1 
ATOM   8222  C  CE1 . PHE D 1 68  ? 154.982 139.545 76.827  1.00 83.40  ? 15  PHE A CE1 1 
ATOM   8223  C  CE2 . PHE D 1 68  ? 153.808 141.481 76.106  1.00 87.63  ? 15  PHE A CE2 1 
ATOM   8224  C  CZ  . PHE D 1 68  ? 154.972 140.883 76.521  1.00 85.99  ? 15  PHE A CZ  1 
ATOM   8225  N  N   . THR D 1 69  ? 148.945 137.570 74.277  1.00 67.37  ? 16  THR A N   1 
ATOM   8226  C  CA  . THR D 1 69  ? 147.737 136.791 74.034  1.00 66.43  ? 16  THR A CA  1 
ATOM   8227  C  C   . THR D 1 69  ? 148.000 135.669 73.038  1.00 69.24  ? 16  THR A C   1 
ATOM   8228  O  O   . THR D 1 69  ? 147.539 134.539 73.232  1.00 71.16  ? 16  THR A O   1 
ATOM   8229  C  CB  . THR D 1 69  ? 146.616 137.696 73.532  1.00 70.78  ? 16  THR A CB  1 
ATOM   8230  O  OG1 . THR D 1 69  ? 146.305 138.666 74.535  1.00 72.63  ? 16  THR A OG1 1 
ATOM   8231  C  CG2 . THR D 1 69  ? 145.374 136.888 73.218  1.00 67.67  ? 16  THR A CG2 1 
ATOM   8232  N  N   . ARG D 1 70  ? 148.743 135.957 71.967  1.00 69.97  ? 17  ARG A N   1 
ATOM   8233  C  CA  . ARG D 1 70  ? 149.076 134.909 71.007  1.00 70.53  ? 17  ARG A CA  1 
ATOM   8234  C  C   . ARG D 1 70  ? 149.942 133.828 71.644  1.00 68.84  ? 17  ARG A C   1 
ATOM   8235  O  O   . ARG D 1 70  ? 149.745 132.634 71.388  1.00 69.20  ? 17  ARG A O   1 
ATOM   8236  C  CB  . ARG D 1 70  ? 149.769 135.510 69.787  1.00 74.38  ? 17  ARG A CB  1 
ATOM   8237  C  CG  . ARG D 1 70  ? 148.829 136.254 68.848  1.00 80.41  ? 17  ARG A CG  1 
ATOM   8238  C  CD  . ARG D 1 70  ? 149.536 136.675 67.569  1.00 89.39  ? 17  ARG A CD  1 
ATOM   8239  N  NE  . ARG D 1 70  ? 150.503 137.742 67.798  1.00 97.98  ? 17  ARG A NE  1 
ATOM   8240  C  CZ  . ARG D 1 70  ? 150.302 139.016 67.485  1.00 100.87 ? 17  ARG A CZ  1 
ATOM   8241  N  NH1 . ARG D 1 70  ? 149.183 139.417 66.904  1.00 99.34  ? 17  ARG A NH1 1 
ATOM   8242  N  NH2 . ARG D 1 70  ? 151.248 139.909 67.761  1.00 98.24  ? 17  ARG A NH2 1 
ATOM   8243  N  N   . ILE D 1 71  ? 150.897 134.225 72.486  1.00 67.25  ? 18  ILE A N   1 
ATOM   8244  C  CA  . ILE D 1 71  ? 151.743 133.247 73.169  1.00 61.75  ? 18  ILE A CA  1 
ATOM   8245  C  C   . ILE D 1 71  ? 150.901 132.336 74.051  1.00 60.36  ? 18  ILE A C   1 
ATOM   8246  O  O   . ILE D 1 71  ? 151.049 131.107 74.031  1.00 65.21  ? 18  ILE A O   1 
ATOM   8247  C  CB  . ILE D 1 71  ? 152.835 133.957 73.988  1.00 64.18  ? 18  ILE A CB  1 
ATOM   8248  C  CG1 . ILE D 1 71  ? 153.824 134.668 73.069  1.00 64.22  ? 18  ILE A CG1 1 
ATOM   8249  C  CG2 . ILE D 1 71  ? 153.561 132.966 74.874  1.00 64.26  ? 18  ILE A CG2 1 
ATOM   8250  C  CD1 . ILE D 1 71  ? 154.983 135.287 73.804  1.00 65.89  ? 18  ILE A CD1 1 
ATOM   8251  N  N   . LEU D 1 72  ? 150.003 132.924 74.842  1.00 58.42  ? 19  LEU A N   1 
ATOM   8252  C  CA  . LEU D 1 72  ? 149.185 132.120 75.743  1.00 58.08  ? 19  LEU A CA  1 
ATOM   8253  C  C   . LEU D 1 72  ? 148.233 131.217 74.973  1.00 60.99  ? 19  LEU A C   1 
ATOM   8254  O  O   . LEU D 1 72  ? 148.004 130.070 75.370  1.00 62.69  ? 19  LEU A O   1 
ATOM   8255  C  CB  . LEU D 1 72  ? 148.419 133.021 76.705  1.00 56.92  ? 19  LEU A CB  1 
ATOM   8256  C  CG  . LEU D 1 72  ? 149.281 133.721 77.751  1.00 53.25  ? 19  LEU A CG  1 
ATOM   8257  C  CD1 . LEU D 1 72  ? 148.424 134.539 78.682  1.00 45.42  ? 19  LEU A CD1 1 
ATOM   8258  C  CD2 . LEU D 1 72  ? 150.084 132.701 78.524  1.00 53.07  ? 19  LEU A CD2 1 
ATOM   8259  N  N   . ASP D 1 73  ? 147.666 131.711 73.872  1.00 62.82  ? 20  ASP A N   1 
ATOM   8260  C  CA  . ASP D 1 73  ? 146.799 130.873 73.052  1.00 63.93  ? 20  ASP A CA  1 
ATOM   8261  C  C   . ASP D 1 73  ? 147.567 129.703 72.454  1.00 65.18  ? 20  ASP A C   1 
ATOM   8262  O  O   . ASP D 1 73  ? 147.028 128.599 72.328  1.00 68.72  ? 20  ASP A O   1 
ATOM   8263  C  CB  . ASP D 1 73  ? 146.149 131.706 71.952  1.00 71.54  ? 20  ASP A CB  1 
ATOM   8264  C  CG  . ASP D 1 73  ? 145.051 132.608 72.476  1.00 79.70  ? 20  ASP A CG  1 
ATOM   8265  O  OD1 . ASP D 1 73  ? 144.816 132.611 73.700  1.00 76.44  ? 20  ASP A OD1 1 
ATOM   8266  O  OD2 . ASP D 1 73  ? 144.419 133.312 71.662  1.00 86.32  ? 20  ASP A OD2 1 
ATOM   8267  N  N   . ARG D 1 74  ? 148.822 129.926 72.062  1.00 65.33  ? 21  ARG A N   1 
ATOM   8268  C  CA  . ARG D 1 74  ? 149.619 128.831 71.522  1.00 65.03  ? 21  ARG A CA  1 
ATOM   8269  C  C   . ARG D 1 74  ? 149.981 127.815 72.598  1.00 64.82  ? 21  ARG A C   1 
ATOM   8270  O  O   . ARG D 1 74  ? 150.031 126.611 72.327  1.00 62.93  ? 21  ARG A O   1 
ATOM   8271  C  CB  . ARG D 1 74  ? 150.881 129.371 70.857  1.00 68.37  ? 21  ARG A CB  1 
ATOM   8272  C  CG  . ARG D 1 74  ? 151.640 128.332 70.055  1.00 73.64  ? 21  ARG A CG  1 
ATOM   8273  C  CD  . ARG D 1 74  ? 153.017 128.835 69.677  1.00 80.26  ? 21  ARG A CD  1 
ATOM   8274  N  NE  . ARG D 1 74  ? 153.749 129.296 70.850  1.00 88.38  ? 21  ARG A NE  1 
ATOM   8275  C  CZ  . ARG D 1 74  ? 154.493 128.518 71.623  1.00 86.20  ? 21  ARG A CZ  1 
ATOM   8276  N  NH1 . ARG D 1 74  ? 154.648 127.231 71.363  1.00 88.05  ? 21  ARG A NH1 1 
ATOM   8277  N  NH2 . ARG D 1 74  ? 155.096 129.045 72.685  1.00 80.51  ? 21  ARG A NH2 1 
ATOM   8278  N  N   . LEU D 1 75  ? 150.251 128.276 73.822  1.00 63.55  ? 22  LEU A N   1 
ATOM   8279  C  CA  . LEU D 1 75  ? 150.668 127.353 74.877  1.00 56.36  ? 22  LEU A CA  1 
ATOM   8280  C  C   . LEU D 1 75  ? 149.561 126.369 75.236  1.00 61.01  ? 22  LEU A C   1 
ATOM   8281  O  O   . LEU D 1 75  ? 149.832 125.192 75.494  1.00 68.27  ? 22  LEU A O   1 
ATOM   8282  C  CB  . LEU D 1 75  ? 151.114 128.124 76.115  1.00 56.84  ? 22  LEU A CB  1 
ATOM   8283  C  CG  . LEU D 1 75  ? 152.476 128.804 76.010  1.00 61.07  ? 22  LEU A CG  1 
ATOM   8284  C  CD1 . LEU D 1 75  ? 152.876 129.381 77.345  1.00 55.49  ? 22  LEU A CD1 1 
ATOM   8285  C  CD2 . LEU D 1 75  ? 153.509 127.819 75.520  1.00 58.82  ? 22  LEU A CD2 1 
ATOM   8286  N  N   . LEU D 1 76  ? 148.315 126.829 75.271  1.00 59.82  ? 23  LEU A N   1 
ATOM   8287  C  CA  . LEU D 1 76  ? 147.192 125.979 75.641  1.00 58.66  ? 23  LEU A CA  1 
ATOM   8288  C  C   . LEU D 1 76  ? 146.584 125.235 74.461  1.00 61.30  ? 23  LEU A C   1 
ATOM   8289  O  O   . LEU D 1 76  ? 145.648 124.455 74.657  1.00 65.39  ? 23  LEU A O   1 
ATOM   8290  C  CB  . LEU D 1 76  ? 146.110 126.811 76.328  1.00 55.31  ? 23  LEU A CB  1 
ATOM   8291  C  CG  . LEU D 1 76  ? 146.513 127.458 77.647  1.00 53.26  ? 23  LEU A CG  1 
ATOM   8292  C  CD1 . LEU D 1 76  ? 145.419 128.376 78.139  1.00 54.97  ? 23  LEU A CD1 1 
ATOM   8293  C  CD2 . LEU D 1 76  ? 146.820 126.396 78.672  1.00 48.87  ? 23  LEU A CD2 1 
ATOM   8294  N  N   . ASP D 1 77  ? 147.086 125.450 73.252  1.00 66.50  ? 24  ASP A N   1 
ATOM   8295  C  CA  . ASP D 1 77  ? 146.560 124.783 72.067  1.00 70.06  ? 24  ASP A CA  1 
ATOM   8296  C  C   . ASP D 1 77  ? 147.024 123.332 72.062  1.00 71.65  ? 24  ASP A C   1 
ATOM   8297  O  O   . ASP D 1 77  ? 148.215 123.054 71.900  1.00 70.32  ? 24  ASP A O   1 
ATOM   8298  C  CB  . ASP D 1 77  ? 147.032 125.515 70.815  1.00 75.27  ? 24  ASP A CB  1 
ATOM   8299  C  CG  . ASP D 1 77  ? 146.391 124.990 69.549  1.00 86.86  ? 24  ASP A CG  1 
ATOM   8300  O  OD1 . ASP D 1 77  ? 145.318 124.360 69.631  1.00 88.90  ? 24  ASP A OD1 1 
ATOM   8301  O  OD2 . ASP D 1 77  ? 146.971 125.207 68.466  1.00 94.75  ? 24  ASP A OD2 1 
ATOM   8302  N  N   . GLY D 1 78  ? 146.088 122.403 72.229  1.00 73.58  ? 25  GLY A N   1 
ATOM   8303  C  CA  . GLY D 1 78  ? 146.443 121.000 72.295  1.00 72.15  ? 25  GLY A CA  1 
ATOM   8304  C  C   . GLY D 1 78  ? 147.078 120.563 73.593  1.00 70.37  ? 25  GLY A C   1 
ATOM   8305  O  O   . GLY D 1 78  ? 147.805 119.566 73.609  1.00 67.40  ? 25  GLY A O   1 
ATOM   8306  N  N   . TYR D 1 79  ? 146.835 121.284 74.682  1.00 67.43  ? 26  TYR A N   1 
ATOM   8307  C  CA  . TYR D 1 79  ? 147.387 120.955 75.987  1.00 60.49  ? 26  TYR A CA  1 
ATOM   8308  C  C   . TYR D 1 79  ? 146.359 120.164 76.781  1.00 63.80  ? 26  TYR A C   1 
ATOM   8309  O  O   . TYR D 1 79  ? 145.196 120.566 76.874  1.00 66.38  ? 26  TYR A O   1 
ATOM   8310  C  CB  . TYR D 1 79  ? 147.783 122.225 76.742  1.00 57.66  ? 26  TYR A CB  1 
ATOM   8311  C  CG  . TYR D 1 79  ? 148.421 121.984 78.089  1.00 54.10  ? 26  TYR A CG  1 
ATOM   8312  C  CD1 . TYR D 1 79  ? 147.646 121.846 79.229  1.00 53.22  ? 26  TYR A CD1 1 
ATOM   8313  C  CD2 . TYR D 1 79  ? 149.794 121.905 78.222  1.00 50.04  ? 26  TYR A CD2 1 
ATOM   8314  C  CE1 . TYR D 1 79  ? 148.218 121.627 80.453  1.00 51.74  ? 26  TYR A CE1 1 
ATOM   8315  C  CE2 . TYR D 1 79  ? 150.375 121.689 79.445  1.00 52.30  ? 26  TYR A CE2 1 
ATOM   8316  C  CZ  . TYR D 1 79  ? 149.584 121.552 80.558  1.00 52.97  ? 26  TYR A CZ  1 
ATOM   8317  O  OH  . TYR D 1 79  ? 150.158 121.339 81.788  1.00 49.91  ? 26  TYR A OH  1 
ATOM   8318  N  N   . ASP D 1 80  ? 146.790 119.046 77.347  1.00 60.64  ? 27  ASP A N   1 
ATOM   8319  C  CA  . ASP D 1 80  ? 145.936 118.181 78.151  1.00 56.95  ? 27  ASP A CA  1 
ATOM   8320  C  C   . ASP D 1 80  ? 146.391 118.279 79.599  1.00 52.68  ? 27  ASP A C   1 
ATOM   8321  O  O   . ASP D 1 80  ? 147.472 117.796 79.946  1.00 56.95  ? 27  ASP A O   1 
ATOM   8322  C  CB  . ASP D 1 80  ? 146.006 116.743 77.649  1.00 58.41  ? 27  ASP A CB  1 
ATOM   8323  C  CG  . ASP D 1 80  ? 144.850 115.908 78.128  1.00 62.75  ? 27  ASP A CG  1 
ATOM   8324  O  OD1 . ASP D 1 80  ? 143.923 116.477 78.733  1.00 63.56  ? 27  ASP A OD1 1 
ATOM   8325  O  OD2 . ASP D 1 80  ? 144.866 114.684 77.901  1.00 66.11  ? 27  ASP A OD2 1 
ATOM   8326  N  N   . ASN D 1 81  ? 145.571 118.896 80.445  1.00 50.01  ? 28  ASN A N   1 
ATOM   8327  C  CA  . ASN D 1 81  ? 145.942 119.073 81.841  1.00 50.08  ? 28  ASN A CA  1 
ATOM   8328  C  C   . ASN D 1 81  ? 145.655 117.850 82.697  1.00 53.45  ? 28  ASN A C   1 
ATOM   8329  O  O   . ASN D 1 81  ? 145.957 117.871 83.892  1.00 53.65  ? 28  ASN A O   1 
ATOM   8330  C  CB  . ASN D 1 81  ? 145.233 120.289 82.433  1.00 47.43  ? 28  ASN A CB  1 
ATOM   8331  C  CG  . ASN D 1 81  ? 143.757 120.289 82.168  1.00 50.26  ? 28  ASN A CG  1 
ATOM   8332  O  OD1 . ASN D 1 81  ? 143.194 119.293 81.727  1.00 59.48  ? 28  ASN A OD1 1 
ATOM   8333  N  ND2 . ASN D 1 81  ? 143.114 121.412 82.435  1.00 47.74  ? 28  ASN A ND2 1 
ATOM   8334  N  N   . ARG D 1 82  ? 145.071 116.795 82.130  1.00 54.93  ? 29  ARG A N   1 
ATOM   8335  C  CA  . ARG D 1 82  ? 144.908 115.559 82.880  1.00 51.31  ? 29  ARG A CA  1 
ATOM   8336  C  C   . ARG D 1 82  ? 146.218 114.813 83.051  1.00 49.51  ? 29  ARG A C   1 
ATOM   8337  O  O   . ARG D 1 82  ? 146.338 114.007 83.975  1.00 54.81  ? 29  ARG A O   1 
ATOM   8338  C  CB  . ARG D 1 82  ? 143.908 114.640 82.186  1.00 52.39  ? 29  ARG A CB  1 
ATOM   8339  C  CG  . ARG D 1 82  ? 142.672 115.324 81.679  1.00 49.61  ? 29  ARG A CG  1 
ATOM   8340  C  CD  . ARG D 1 82  ? 141.682 114.307 81.177  1.00 53.80  ? 29  ARG A CD  1 
ATOM   8341  N  NE  . ARG D 1 82  ? 140.639 114.932 80.378  1.00 64.46  ? 29  ARG A NE  1 
ATOM   8342  C  CZ  . ARG D 1 82  ? 140.542 114.824 79.061  1.00 64.80  ? 29  ARG A CZ  1 
ATOM   8343  N  NH1 . ARG D 1 82  ? 141.391 114.090 78.363  1.00 51.50  ? 29  ARG A NH1 1 
ATOM   8344  N  NH2 . ARG D 1 82  ? 139.566 115.468 78.430  1.00 78.75  ? 29  ARG A NH2 1 
ATOM   8345  N  N   . LEU D 1 83  ? 147.196 115.061 82.189  1.00 47.34  ? 30  LEU A N   1 
ATOM   8346  C  CA  . LEU D 1 83  ? 148.411 114.264 82.127  1.00 47.52  ? 30  LEU A CA  1 
ATOM   8347  C  C   . LEU D 1 83  ? 149.566 115.020 82.766  1.00 45.94  ? 30  LEU A C   1 
ATOM   8348  O  O   . LEU D 1 83  ? 149.849 116.161 82.391  1.00 46.67  ? 30  LEU A O   1 
ATOM   8349  C  CB  . LEU D 1 83  ? 148.744 113.916 80.678  1.00 47.48  ? 30  LEU A CB  1 
ATOM   8350  C  CG  . LEU D 1 83  ? 147.591 113.295 79.894  1.00 45.92  ? 30  LEU A CG  1 
ATOM   8351  C  CD1 . LEU D 1 83  ? 148.023 112.963 78.487  1.00 45.35  ? 30  LEU A CD1 1 
ATOM   8352  C  CD2 . LEU D 1 83  ? 147.093 112.058 80.596  1.00 44.30  ? 30  LEU A CD2 1 
ATOM   8353  N  N   . ARG D 1 84  ? 150.238 114.374 83.714  1.00 45.43  ? 31  ARG A N   1 
ATOM   8354  C  CA  . ARG D 1 84  ? 151.382 114.987 84.360  1.00 44.88  ? 31  ARG A CA  1 
ATOM   8355  C  C   . ARG D 1 84  ? 152.520 115.146 83.355  1.00 49.20  ? 31  ARG A C   1 
ATOM   8356  O  O   . ARG D 1 84  ? 152.630 114.370 82.404  1.00 52.31  ? 31  ARG A O   1 
ATOM   8357  C  CB  . ARG D 1 84  ? 151.847 114.143 85.541  1.00 41.36  ? 31  ARG A CB  1 
ATOM   8358  C  CG  . ARG D 1 84  ? 152.413 112.803 85.138  1.00 44.57  ? 31  ARG A CG  1 
ATOM   8359  C  CD  . ARG D 1 84  ? 152.927 112.023 86.317  1.00 44.66  ? 31  ARG A CD  1 
ATOM   8360  N  NE  . ARG D 1 84  ? 153.415 110.715 85.907  1.00 50.90  ? 31  ARG A NE  1 
ATOM   8361  C  CZ  . ARG D 1 84  ? 154.666 110.460 85.555  1.00 54.08  ? 31  ARG A CZ  1 
ATOM   8362  N  NH1 . ARG D 1 84  ? 155.589 111.405 85.554  1.00 50.28  ? 31  ARG A NH1 1 
ATOM   8363  N  NH2 . ARG D 1 84  ? 154.999 109.225 85.196  1.00 55.77  ? 31  ARG A NH2 1 
ATOM   8364  N  N   . PRO D 1 85  ? 153.369 116.155 83.532  1.00 46.79  ? 32  PRO A N   1 
ATOM   8365  C  CA  . PRO D 1 85  ? 154.491 116.338 82.607  1.00 49.87  ? 32  PRO A CA  1 
ATOM   8366  C  C   . PRO D 1 85  ? 155.481 115.193 82.684  1.00 59.02  ? 32  PRO A C   1 
ATOM   8367  O  O   . PRO D 1 85  ? 156.151 115.009 83.703  1.00 63.86  ? 32  PRO A O   1 
ATOM   8368  C  CB  . PRO D 1 85  ? 155.120 117.653 83.079  1.00 49.52  ? 32  PRO A CB  1 
ATOM   8369  C  CG  . PRO D 1 85  ? 154.077 118.308 83.895  1.00 49.15  ? 32  PRO A CG  1 
ATOM   8370  C  CD  . PRO D 1 85  ? 153.323 117.217 84.542  1.00 43.61  ? 32  PRO A CD  1 
ATOM   8371  N  N   . GLY D 1 86  ? 155.590 114.425 81.609  1.00 56.44  ? 33  GLY A N   1 
ATOM   8372  C  CA  . GLY D 1 86  ? 156.469 113.282 81.579  1.00 59.41  ? 33  GLY A CA  1 
ATOM   8373  C  C   . GLY D 1 86  ? 155.806 111.941 81.776  1.00 59.83  ? 33  GLY A C   1 
ATOM   8374  O  O   . GLY D 1 86  ? 156.511 110.962 82.033  1.00 64.14  ? 33  GLY A O   1 
ATOM   8375  N  N   . LEU D 1 87  ? 154.483 111.863 81.659  1.00 57.47  ? 34  LEU A N   1 
ATOM   8376  C  CA  . LEU D 1 87  ? 153.776 110.600 81.829  1.00 56.05  ? 34  LEU A CA  1 
ATOM   8377  C  C   . LEU D 1 87  ? 154.276 109.579 80.820  1.00 64.19  ? 34  LEU A C   1 
ATOM   8378  O  O   . LEU D 1 87  ? 154.198 109.800 79.609  1.00 67.32  ? 34  LEU A O   1 
ATOM   8379  C  CB  . LEU D 1 87  ? 152.274 110.823 81.672  1.00 48.95  ? 34  LEU A CB  1 
ATOM   8380  C  CG  . LEU D 1 87  ? 151.292 109.725 82.082  1.00 48.76  ? 34  LEU A CG  1 
ATOM   8381  C  CD1 . LEU D 1 87  ? 149.945 110.338 82.389  1.00 45.35  ? 34  LEU A CD1 1 
ATOM   8382  C  CD2 . LEU D 1 87  ? 151.134 108.678 81.003  1.00 52.01  ? 34  LEU A CD2 1 
ATOM   8383  N  N   . GLY D 1 88  ? 154.794 108.463 81.322  1.00 67.02  ? 35  GLY A N   1 
ATOM   8384  C  CA  . GLY D 1 88  ? 155.345 107.427 80.480  1.00 67.58  ? 35  GLY A CA  1 
ATOM   8385  C  C   . GLY D 1 88  ? 156.772 107.653 80.040  1.00 71.81  ? 35  GLY A C   1 
ATOM   8386  O  O   . GLY D 1 88  ? 157.343 106.777 79.380  1.00 74.32  ? 35  GLY A O   1 
ATOM   8387  N  N   . GLU D 1 89  ? 157.371 108.792 80.384  1.00 70.22  ? 36  GLU A N   1 
ATOM   8388  C  CA  . GLU D 1 89  ? 158.744 109.092 79.999  1.00 71.49  ? 36  GLU A CA  1 
ATOM   8389  C  C   . GLU D 1 89  ? 159.670 109.201 81.202  1.00 73.86  ? 36  GLU A C   1 
ATOM   8390  O  O   . GLU D 1 89  ? 160.660 108.468 81.274  1.00 75.70  ? 36  GLU A O   1 
ATOM   8391  C  CB  . GLU D 1 89  ? 158.781 110.382 79.175  1.00 75.47  ? 36  GLU A CB  1 
ATOM   8392  C  CG  . GLU D 1 89  ? 160.180 110.883 78.888  1.00 84.40  ? 36  GLU A CG  1 
ATOM   8393  C  CD  . GLU D 1 89  ? 160.177 112.191 78.128  1.00 100.56 ? 36  GLU A CD  1 
ATOM   8394  O  OE1 . GLU D 1 89  ? 159.102 112.579 77.622  1.00 103.82 ? 36  GLU A OE1 1 
ATOM   8395  O  OE2 . GLU D 1 89  ? 161.245 112.833 78.040  1.00 103.73 ? 36  GLU A OE2 1 
ATOM   8396  N  N   . ARG D 1 90  ? 159.384 110.089 82.152  1.00 72.81  ? 37  ARG A N   1 
ATOM   8397  C  CA  . ARG D 1 90  ? 160.272 110.272 83.291  1.00 69.93  ? 37  ARG A CA  1 
ATOM   8398  C  C   . ARG D 1 90  ? 159.486 110.832 84.465  1.00 65.32  ? 37  ARG A C   1 
ATOM   8399  O  O   . ARG D 1 90  ? 158.371 111.335 84.311  1.00 67.66  ? 37  ARG A O   1 
ATOM   8400  C  CB  . ARG D 1 90  ? 161.460 111.179 82.943  1.00 71.42  ? 37  ARG A CB  1 
ATOM   8401  C  CG  . ARG D 1 90  ? 161.129 112.396 82.093  1.00 72.67  ? 37  ARG A CG  1 
ATOM   8402  C  CD  . ARG D 1 90  ? 161.048 113.658 82.929  1.00 73.75  ? 37  ARG A CD  1 
ATOM   8403  N  NE  . ARG D 1 90  ? 160.684 114.822 82.130  1.00 82.57  ? 37  ARG A NE  1 
ATOM   8404  C  CZ  . ARG D 1 90  ? 160.276 115.979 82.634  1.00 84.47  ? 37  ARG A CZ  1 
ATOM   8405  N  NH1 . ARG D 1 90  ? 160.166 116.164 83.939  1.00 76.93  ? 37  ARG A NH1 1 
ATOM   8406  N  NH2 . ARG D 1 90  ? 159.960 116.972 81.808  1.00 84.47  ? 37  ARG A NH2 1 
ATOM   8407  N  N   . VAL D 1 91  ? 160.093 110.739 85.641  1.00 57.88  ? 38  VAL A N   1 
ATOM   8408  C  CA  . VAL D 1 91  ? 159.439 111.086 86.896  1.00 50.38  ? 38  VAL A CA  1 
ATOM   8409  C  C   . VAL D 1 91  ? 159.389 112.599 87.048  1.00 55.29  ? 38  VAL A C   1 
ATOM   8410  O  O   . VAL D 1 91  ? 160.378 113.294 86.793  1.00 64.63  ? 38  VAL A O   1 
ATOM   8411  C  CB  . VAL D 1 91  ? 160.173 110.429 88.074  1.00 49.31  ? 38  VAL A CB  1 
ATOM   8412  C  CG1 . VAL D 1 91  ? 159.718 111.002 89.390  1.00 45.50  ? 38  VAL A CG1 1 
ATOM   8413  C  CG2 . VAL D 1 91  ? 159.959 108.937 88.046  1.00 54.76  ? 38  VAL A CG2 1 
ATOM   8414  N  N   . THR D 1 92  ? 158.233 113.114 87.457  1.00 49.93  ? 39  THR A N   1 
ATOM   8415  C  CA  . THR D 1 92  ? 158.091 114.540 87.723  1.00 47.87  ? 39  THR A CA  1 
ATOM   8416  C  C   . THR D 1 92  ? 158.748 114.896 89.049  1.00 49.58  ? 39  THR A C   1 
ATOM   8417  O  O   . THR D 1 92  ? 158.514 114.237 90.064  1.00 48.93  ? 39  THR A O   1 
ATOM   8418  C  CB  . THR D 1 92  ? 156.614 114.922 87.745  1.00 44.54  ? 39  THR A CB  1 
ATOM   8419  O  OG1 . THR D 1 92  ? 156.032 114.619 86.475  1.00 51.33  ? 39  THR A OG1 1 
ATOM   8420  C  CG2 . THR D 1 92  ? 156.438 116.395 88.032  1.00 41.33  ? 39  THR A CG2 1 
ATOM   8421  N  N   . GLU D 1 93  ? 159.579 115.935 89.039  1.00 49.51  ? 40  GLU A N   1 
ATOM   8422  C  CA  . GLU D 1 93  ? 160.281 116.401 90.227  1.00 47.08  ? 40  GLU A CA  1 
ATOM   8423  C  C   . GLU D 1 93  ? 159.715 117.751 90.631  1.00 43.19  ? 40  GLU A C   1 
ATOM   8424  O  O   . GLU D 1 93  ? 159.732 118.696 89.838  1.00 46.54  ? 40  GLU A O   1 
ATOM   8425  C  CB  . GLU D 1 93  ? 161.784 116.507 89.977  1.00 51.73  ? 40  GLU A CB  1 
ATOM   8426  C  CG  . GLU D 1 93  ? 162.434 115.202 89.563  1.00 65.55  ? 40  GLU A CG  1 
ATOM   8427  C  CD  . GLU D 1 93  ? 163.921 115.342 89.292  1.00 89.83  ? 40  GLU A CD  1 
ATOM   8428  O  OE1 . GLU D 1 93  ? 164.531 116.314 89.784  1.00 95.19  ? 40  GLU A OE1 1 
ATOM   8429  O  OE2 . GLU D 1 93  ? 164.480 114.480 88.582  1.00 94.54  ? 40  GLU A OE2 1 
ATOM   8430  N  N   . VAL D 1 94  ? 159.228 117.839 91.863  1.00 39.24  ? 41  VAL A N   1 
ATOM   8431  C  CA  . VAL D 1 94  ? 158.658 119.061 92.414  1.00 38.82  ? 41  VAL A CA  1 
ATOM   8432  C  C   . VAL D 1 94  ? 159.551 119.520 93.554  1.00 41.86  ? 41  VAL A C   1 
ATOM   8433  O  O   . VAL D 1 94  ? 159.890 118.729 94.438  1.00 49.24  ? 41  VAL A O   1 
ATOM   8434  C  CB  . VAL D 1 94  ? 157.213 118.845 92.897  1.00 36.54  ? 41  VAL A CB  1 
ATOM   8435  C  CG1 . VAL D 1 94  ? 156.642 120.127 93.456  1.00 35.26  ? 41  VAL A CG1 1 
ATOM   8436  C  CG2 . VAL D 1 94  ? 156.351 118.339 91.766  1.00 35.85  ? 41  VAL A CG2 1 
ATOM   8437  N  N   . LYS D 1 95  ? 159.950 120.784 93.523  1.00 35.52  ? 42  LYS A N   1 
ATOM   8438  C  CA  . LYS D 1 95  ? 160.758 121.373 94.579  1.00 37.83  ? 42  LYS A CA  1 
ATOM   8439  C  C   . LYS D 1 95  ? 159.874 122.272 95.425  1.00 40.51  ? 42  LYS A C   1 
ATOM   8440  O  O   . LYS D 1 95  ? 159.124 123.089 94.886  1.00 42.12  ? 42  LYS A O   1 
ATOM   8441  C  CB  . LYS D 1 95  ? 161.934 122.151 93.996  1.00 42.94  ? 42  LYS A CB  1 
ATOM   8442  C  CG  . LYS D 1 95  ? 162.829 121.295 93.135  1.00 47.84  ? 42  LYS A CG  1 
ATOM   8443  C  CD  . LYS D 1 95  ? 164.037 122.048 92.641  1.00 62.37  ? 42  LYS A CD  1 
ATOM   8444  C  CE  . LYS D 1 95  ? 164.878 121.159 91.747  1.00 71.28  ? 42  LYS A CE  1 
ATOM   8445  N  NZ  . LYS D 1 95  ? 165.934 121.919 91.030  1.00 78.90  ? 42  LYS A NZ  1 
ATOM   8446  N  N   . THR D 1 96  ? 159.952 122.112 96.739  1.00 39.21  ? 43  THR A N   1 
ATOM   8447  C  CA  . THR D 1 96  ? 159.025 122.753 97.653  1.00 34.98  ? 43  THR A CA  1 
ATOM   8448  C  C   . THR D 1 96  ? 159.773 123.578 98.687  1.00 37.68  ? 43  THR A C   1 
ATOM   8449  O  O   . THR D 1 96  ? 160.880 123.234 99.100  1.00 41.56  ? 43  THR A O   1 
ATOM   8450  C  CB  . THR D 1 96  ? 158.161 121.720 98.374  1.00 36.63  ? 43  THR A CB  1 
ATOM   8451  O  OG1 . THR D 1 96  ? 157.760 120.703 97.452  1.00 41.33  ? 43  THR A OG1 1 
ATOM   8452  C  CG2 . THR D 1 96  ? 156.927 122.374 98.955  1.00 36.40  ? 43  THR A CG2 1 
ATOM   8453  N  N   . ASP D 1 97  ? 159.150 124.677 99.100  1.00 40.56  ? 44  ASP A N   1 
ATOM   8454  C  CA  . ASP D 1 97  ? 159.589 125.381 100.296 1.00 38.23  ? 44  ASP A CA  1 
ATOM   8455  C  C   . ASP D 1 97  ? 158.392 126.027 100.975 1.00 37.68  ? 44  ASP A C   1 
ATOM   8456  O  O   . ASP D 1 97  ? 157.313 126.168 100.392 1.00 37.97  ? 44  ASP A O   1 
ATOM   8457  C  CB  . ASP D 1 97  ? 160.676 126.419 99.999  1.00 42.65  ? 44  ASP A CB  1 
ATOM   8458  C  CG  . ASP D 1 97  ? 160.398 127.220 98.761  1.00 53.39  ? 44  ASP A CG  1 
ATOM   8459  O  OD1 . ASP D 1 97  ? 159.955 126.627 97.758  1.00 55.58  ? 44  ASP A OD1 1 
ATOM   8460  O  OD2 . ASP D 1 97  ? 160.636 128.445 98.786  1.00 58.16  ? 44  ASP A OD2 1 
ATOM   8461  N  N   . ILE D 1 98  ? 158.589 126.386 102.237 1.00 38.55  ? 45  ILE A N   1 
ATOM   8462  C  CA  . ILE D 1 98  ? 157.527 126.912 103.082 1.00 33.79  ? 45  ILE A CA  1 
ATOM   8463  C  C   . ILE D 1 98  ? 158.029 128.167 103.774 1.00 34.44  ? 45  ILE A C   1 
ATOM   8464  O  O   . ILE D 1 98  ? 159.145 128.186 104.306 1.00 38.95  ? 45  ILE A O   1 
ATOM   8465  C  CB  . ILE D 1 98  ? 157.063 125.877 104.122 1.00 33.28  ? 45  ILE A CB  1 
ATOM   8466  C  CG1 . ILE D 1 98  ? 156.498 124.639 103.435 1.00 30.54  ? 45  ILE A CG1 1 
ATOM   8467  C  CG2 . ILE D 1 98  ? 156.025 126.470 105.030 1.00 32.77  ? 45  ILE A CG2 1 
ATOM   8468  C  CD1 . ILE D 1 98  ? 156.040 123.586 104.398 1.00 30.29  ? 45  ILE A CD1 1 
ATOM   8469  N  N   . PHE D 1 99  ? 157.209 129.212 103.760 1.00 32.07  ? 46  PHE A N   1 
ATOM   8470  C  CA  . PHE D 1 99  ? 157.446 130.415 104.551 1.00 29.32  ? 46  PHE A CA  1 
ATOM   8471  C  C   . PHE D 1 99  ? 156.322 130.518 105.574 1.00 31.24  ? 46  PHE A C   1 
ATOM   8472  O  O   . PHE D 1 99  ? 155.211 130.927 105.240 1.00 32.72  ? 46  PHE A O   1 
ATOM   8473  C  CB  . PHE D 1 99  ? 157.503 131.655 103.672 1.00 28.80  ? 46  PHE A CB  1 
ATOM   8474  C  CG  . PHE D 1 99  ? 157.925 132.889 104.405 1.00 33.57  ? 46  PHE A CG  1 
ATOM   8475  C  CD1 . PHE D 1 99  ? 159.238 133.063 104.782 1.00 36.42  ? 46  PHE A CD1 1 
ATOM   8476  C  CD2 . PHE D 1 99  ? 157.013 133.875 104.719 1.00 35.75  ? 46  PHE A CD2 1 
ATOM   8477  C  CE1 . PHE D 1 99  ? 159.629 134.189 105.454 1.00 36.19  ? 46  PHE A CE1 1 
ATOM   8478  C  CE2 . PHE D 1 99  ? 157.405 135.004 105.394 1.00 33.17  ? 46  PHE A CE2 1 
ATOM   8479  C  CZ  . PHE D 1 99  ? 158.710 135.160 105.760 1.00 36.07  ? 46  PHE A CZ  1 
ATOM   8480  N  N   . VAL D 1 100 ? 156.606 130.144 106.817 1.00 31.02  ? 47  VAL A N   1 
ATOM   8481  C  CA  . VAL D 1 100 ? 155.622 130.227 107.890 1.00 29.57  ? 47  VAL A CA  1 
ATOM   8482  C  C   . VAL D 1 100 ? 155.473 131.692 108.280 1.00 33.69  ? 47  VAL A C   1 
ATOM   8483  O  O   . VAL D 1 100 ? 156.366 132.268 108.904 1.00 41.17  ? 47  VAL A O   1 
ATOM   8484  C  CB  . VAL D 1 100 ? 156.031 129.372 109.090 1.00 28.67  ? 47  VAL A CB  1 
ATOM   8485  C  CG1 . VAL D 1 100 ? 154.991 129.465 110.184 1.00 28.36  ? 47  VAL A CG1 1 
ATOM   8486  C  CG2 . VAL D 1 100 ? 156.232 127.939 108.663 1.00 29.25  ? 47  VAL A CG2 1 
ATOM   8487  N  N   . THR D 1 101 ? 154.349 132.305 107.910 1.00 33.81  ? 48  THR A N   1 
ATOM   8488  C  CA  . THR D 1 101 ? 154.131 133.699 108.267 1.00 33.97  ? 48  THR A CA  1 
ATOM   8489  C  C   . THR D 1 101 ? 153.649 133.869 109.701 1.00 40.92  ? 48  THR A C   1 
ATOM   8490  O  O   . THR D 1 101 ? 153.844 134.942 110.279 1.00 46.87  ? 48  THR A O   1 
ATOM   8491  C  CB  . THR D 1 101 ? 153.137 134.349 107.306 1.00 32.28  ? 48  THR A CB  1 
ATOM   8492  O  OG1 . THR D 1 101 ? 151.817 133.875 107.579 1.00 37.72  ? 48  THR A OG1 1 
ATOM   8493  C  CG2 . THR D 1 101 ? 153.499 134.012 105.883 1.00 30.55  ? 48  THR A CG2 1 
ATOM   8494  N  N   . SER D 1 102 ? 153.028 132.847 110.284 1.00 35.58  ? 49  SER A N   1 
ATOM   8495  C  CA  . SER D 1 102 ? 152.601 132.912 111.679 1.00 37.11  ? 49  SER A CA  1 
ATOM   8496  C  C   . SER D 1 102 ? 152.354 131.501 112.174 1.00 36.72  ? 49  SER A C   1 
ATOM   8497  O  O   . SER D 1 102 ? 151.540 130.784 111.594 1.00 41.22  ? 49  SER A O   1 
ATOM   8498  C  CB  . SER D 1 102 ? 151.343 133.747 111.827 1.00 41.82  ? 49  SER A CB  1 
ATOM   8499  O  OG  . SER D 1 102 ? 150.199 132.956 111.584 1.00 45.36  ? 49  SER A OG  1 
ATOM   8500  N  N   . PHE D 1 103 ? 153.035 131.109 113.245 1.00 38.18  ? 50  PHE A N   1 
ATOM   8501  C  CA  . PHE D 1 103 ? 152.827 129.799 113.854 1.00 34.10  ? 50  PHE A CA  1 
ATOM   8502  C  C   . PHE D 1 103 ? 151.735 129.944 114.902 1.00 33.97  ? 50  PHE A C   1 
ATOM   8503  O  O   . PHE D 1 103 ? 151.973 130.449 115.998 1.00 36.28  ? 50  PHE A O   1 
ATOM   8504  C  CB  . PHE D 1 103 ? 154.122 129.266 114.452 1.00 33.02  ? 50  PHE A CB  1 
ATOM   8505  C  CG  . PHE D 1 103 ? 154.044 127.832 114.867 1.00 32.90  ? 50  PHE A CG  1 
ATOM   8506  C  CD1 . PHE D 1 103 ? 154.248 126.824 113.953 1.00 34.87  ? 50  PHE A CD1 1 
ATOM   8507  C  CD2 . PHE D 1 103 ? 153.763 127.491 116.171 1.00 33.91  ? 50  PHE A CD2 1 
ATOM   8508  C  CE1 . PHE D 1 103 ? 154.171 125.510 114.332 1.00 32.08  ? 50  PHE A CE1 1 
ATOM   8509  C  CE2 . PHE D 1 103 ? 153.691 126.178 116.549 1.00 34.33  ? 50  PHE A CE2 1 
ATOM   8510  C  CZ  . PHE D 1 103 ? 153.892 125.189 115.629 1.00 34.98  ? 50  PHE A CZ  1 
ATOM   8511  N  N   . GLY D 1 104 ? 150.540 129.470 114.570 1.00 37.60  ? 51  GLY A N   1 
ATOM   8512  C  CA  . GLY D 1 104 ? 149.344 129.786 115.311 1.00 37.98  ? 51  GLY A CA  1 
ATOM   8513  C  C   . GLY D 1 104 ? 149.230 129.059 116.628 1.00 35.06  ? 51  GLY A C   1 
ATOM   8514  O  O   . GLY D 1 104 ? 150.170 128.410 117.088 1.00 37.45  ? 51  GLY A O   1 
ATOM   8515  N  N   . PRO D 1 105 ? 148.066 129.166 117.265 1.00 35.93  ? 52  PRO A N   1 
ATOM   8516  C  CA  . PRO D 1 105 ? 147.902 128.611 118.610 1.00 36.85  ? 52  PRO A CA  1 
ATOM   8517  C  C   . PRO D 1 105 ? 148.036 127.099 118.625 1.00 38.46  ? 52  PRO A C   1 
ATOM   8518  O  O   . PRO D 1 105 ? 147.646 126.409 117.684 1.00 40.43  ? 52  PRO A O   1 
ATOM   8519  C  CB  . PRO D 1 105 ? 146.484 129.038 118.999 1.00 33.70  ? 52  PRO A CB  1 
ATOM   8520  C  CG  . PRO D 1 105 ? 146.161 130.159 118.093 1.00 38.92  ? 52  PRO A CG  1 
ATOM   8521  C  CD  . PRO D 1 105 ? 146.863 129.875 116.815 1.00 35.46  ? 52  PRO A CD  1 
ATOM   8522  N  N   . VAL D 1 106 ? 148.575 126.590 119.726 1.00 35.77  ? 53  VAL A N   1 
ATOM   8523  C  CA  . VAL D 1 106 ? 148.713 125.161 119.962 1.00 31.81  ? 53  VAL A CA  1 
ATOM   8524  C  C   . VAL D 1 106 ? 147.733 124.767 121.054 1.00 34.32  ? 53  VAL A C   1 
ATOM   8525  O  O   . VAL D 1 106 ? 147.701 125.389 122.120 1.00 46.53  ? 53  VAL A O   1 
ATOM   8526  C  CB  . VAL D 1 106 ? 150.152 124.790 120.348 1.00 33.11  ? 53  VAL A CB  1 
ATOM   8527  C  CG1 . VAL D 1 106 ? 150.227 123.340 120.706 1.00 36.47  ? 53  VAL A CG1 1 
ATOM   8528  C  CG2 . VAL D 1 106 ? 151.095 125.092 119.210 1.00 34.70  ? 53  VAL A CG2 1 
ATOM   8529  N  N   . SER D 1 107 ? 146.931 123.743 120.789 1.00 35.05  ? 54  SER A N   1 
ATOM   8530  C  CA  . SER D 1 107 ? 145.873 123.319 121.696 1.00 42.68  ? 54  SER A CA  1 
ATOM   8531  C  C   . SER D 1 107 ? 146.223 121.966 122.300 1.00 46.61  ? 54  SER A C   1 
ATOM   8532  O  O   . SER D 1 107 ? 146.398 120.988 121.571 1.00 47.29  ? 54  SER A O   1 
ATOM   8533  C  CB  . SER D 1 107 ? 144.538 123.247 120.961 1.00 42.66  ? 54  SER A CB  1 
ATOM   8534  O  OG  . SER D 1 107 ? 143.521 122.756 121.808 1.00 54.20  ? 54  SER A OG  1 
ATOM   8535  N  N   . ASP D 1 108 ? 146.311 121.913 123.631 1.00 46.27  ? 55  ASP A N   1 
ATOM   8536  C  CA  . ASP D 1 108 ? 146.508 120.635 124.310 1.00 46.93  ? 55  ASP A CA  1 
ATOM   8537  C  C   . ASP D 1 108 ? 145.229 119.815 124.321 1.00 52.26  ? 55  ASP A C   1 
ATOM   8538  O  O   . ASP D 1 108 ? 145.271 118.586 124.214 1.00 55.20  ? 55  ASP A O   1 
ATOM   8539  C  CB  . ASP D 1 108 ? 146.980 120.858 125.745 1.00 51.37  ? 55  ASP A CB  1 
ATOM   8540  C  CG  . ASP D 1 108 ? 148.336 121.501 125.822 1.00 58.98  ? 55  ASP A CG  1 
ATOM   8541  O  OD1 . ASP D 1 108 ? 148.946 121.729 124.759 1.00 61.74  ? 55  ASP A OD1 1 
ATOM   8542  O  OD2 . ASP D 1 108 ? 148.795 121.779 126.948 1.00 59.53  ? 55  ASP A OD2 1 
ATOM   8543  N  N   . HIS D 1 109 ? 144.084 120.479 124.470 1.00 51.31  ? 56  HIS A N   1 
ATOM   8544  C  CA  . HIS D 1 109 ? 142.819 119.763 124.570 1.00 51.96  ? 56  HIS A CA  1 
ATOM   8545  C  C   . HIS D 1 109 ? 142.516 118.993 123.295 1.00 55.24  ? 56  HIS A C   1 
ATOM   8546  O  O   . HIS D 1 109 ? 142.059 117.847 123.348 1.00 63.03  ? 56  HIS A O   1 
ATOM   8547  C  CB  . HIS D 1 109 ? 141.695 120.742 124.892 1.00 58.47  ? 56  HIS A CB  1 
ATOM   8548  C  CG  . HIS D 1 109 ? 140.354 120.095 125.033 1.00 77.59  ? 56  HIS A CG  1 
ATOM   8549  N  ND1 . HIS D 1 109 ? 140.143 118.985 125.822 1.00 87.56  ? 56  HIS A ND1 1 
ATOM   8550  C  CD2 . HIS D 1 109 ? 139.154 120.404 124.490 1.00 79.61  ? 56  HIS A CD2 1 
ATOM   8551  C  CE1 . HIS D 1 109 ? 138.871 118.635 125.755 1.00 87.46  ? 56  HIS A CE1 1 
ATOM   8552  N  NE2 . HIS D 1 109 ? 138.249 119.481 124.953 1.00 90.79  ? 56  HIS A NE2 1 
ATOM   8553  N  N   . ASP D 1 110 ? 142.757 119.603 122.140 1.00 52.51  ? 57  ASP A N   1 
ATOM   8554  C  CA  . ASP D 1 110 ? 142.506 118.952 120.862 1.00 52.22  ? 57  ASP A CA  1 
ATOM   8555  C  C   . ASP D 1 110 ? 143.735 118.274 120.277 1.00 48.89  ? 57  ASP A C   1 
ATOM   8556  O  O   . ASP D 1 110 ? 143.608 117.570 119.272 1.00 52.61  ? 57  ASP A O   1 
ATOM   8557  C  CB  . ASP D 1 110 ? 141.960 119.968 119.862 1.00 53.83  ? 57  ASP A CB  1 
ATOM   8558  C  CG  . ASP D 1 110 ? 140.618 120.520 120.273 1.00 61.44  ? 57  ASP A CG  1 
ATOM   8559  O  OD1 . ASP D 1 110 ? 139.807 119.754 120.826 1.00 68.42  ? 57  ASP A OD1 1 
ATOM   8560  O  OD2 . ASP D 1 110 ? 140.369 121.720 120.046 1.00 59.13  ? 57  ASP A OD2 1 
ATOM   8561  N  N   . MET D 1 111 ? 144.904 118.456 120.886 1.00 48.96  ? 58  MET A N   1 
ATOM   8562  C  CA  . MET D 1 111 ? 146.163 117.896 120.395 1.00 48.27  ? 58  MET A CA  1 
ATOM   8563  C  C   . MET D 1 111 ? 146.396 118.271 118.936 1.00 47.68  ? 58  MET A C   1 
ATOM   8564  O  O   . MET D 1 111 ? 146.689 117.430 118.087 1.00 49.88  ? 58  MET A O   1 
ATOM   8565  C  CB  . MET D 1 111 ? 146.208 116.384 120.594 1.00 48.12  ? 58  MET A CB  1 
ATOM   8566  C  CG  . MET D 1 111 ? 146.315 115.973 122.045 1.00 55.19  ? 58  MET A CG  1 
ATOM   8567  S  SD  . MET D 1 111 ? 146.539 114.205 122.271 1.00 88.28  ? 58  MET A SD  1 
ATOM   8568  C  CE  . MET D 1 111 ? 146.576 114.117 124.055 1.00 66.67  ? 58  MET A CE  1 
ATOM   8569  N  N   . GLU D 1 112 ? 146.265 119.562 118.651 1.00 45.59  ? 59  GLU A N   1 
ATOM   8570  C  CA  . GLU D 1 112 ? 146.436 120.088 117.310 1.00 37.92  ? 59  GLU A CA  1 
ATOM   8571  C  C   . GLU D 1 112 ? 147.147 121.429 117.389 1.00 38.03  ? 59  GLU A C   1 
ATOM   8572  O  O   . GLU D 1 112 ? 147.333 121.998 118.464 1.00 45.27  ? 59  GLU A O   1 
ATOM   8573  C  CB  . GLU D 1 112 ? 145.097 120.244 116.591 1.00 37.04  ? 59  GLU A CB  1 
ATOM   8574  C  CG  . GLU D 1 112 ? 144.229 121.328 117.169 1.00 46.72  ? 59  GLU A CG  1 
ATOM   8575  C  CD  . GLU D 1 112 ? 142.855 121.345 116.553 1.00 61.12  ? 59  GLU A CD  1 
ATOM   8576  O  OE1 . GLU D 1 112 ? 142.412 120.282 116.075 1.00 67.60  ? 59  GLU A OE1 1 
ATOM   8577  O  OE2 . GLU D 1 112 ? 142.220 122.419 116.541 1.00 62.54  ? 59  GLU A OE2 1 
ATOM   8578  N  N   . TYR D 1 113 ? 147.563 121.919 116.229 1.00 33.92  ? 60  TYR A N   1 
ATOM   8579  C  CA  . TYR D 1 113 ? 148.152 123.243 116.133 1.00 28.95  ? 60  TYR A CA  1 
ATOM   8580  C  C   . TYR D 1 113 ? 147.784 123.839 114.787 1.00 33.06  ? 60  TYR A C   1 
ATOM   8581  O  O   . TYR D 1 113 ? 147.551 123.116 113.819 1.00 36.43  ? 60  TYR A O   1 
ATOM   8582  C  CB  . TYR D 1 113 ? 149.674 123.207 116.307 1.00 28.54  ? 60  TYR A CB  1 
ATOM   8583  C  CG  . TYR D 1 113 ? 150.419 122.556 115.165 1.00 33.19  ? 60  TYR A CG  1 
ATOM   8584  C  CD1 . TYR D 1 113 ? 150.595 121.184 115.120 1.00 37.91  ? 60  TYR A CD1 1 
ATOM   8585  C  CD2 . TYR D 1 113 ? 150.957 123.314 114.141 1.00 31.63  ? 60  TYR A CD2 1 
ATOM   8586  C  CE1 . TYR D 1 113 ? 151.271 120.592 114.084 1.00 36.60  ? 60  TYR A CE1 1 
ATOM   8587  C  CE2 . TYR D 1 113 ? 151.630 122.731 113.104 1.00 32.97  ? 60  TYR A CE2 1 
ATOM   8588  C  CZ  . TYR D 1 113 ? 151.788 121.372 113.081 1.00 35.61  ? 60  TYR A CZ  1 
ATOM   8589  O  OH  . TYR D 1 113 ? 152.468 120.787 112.045 1.00 33.09  ? 60  TYR A OH  1 
ATOM   8590  N  N   . THR D 1 114 ? 147.739 125.161 114.729 1.00 29.89  ? 61  THR A N   1 
ATOM   8591  C  CA  . THR D 1 114 ? 147.441 125.883 113.504 1.00 29.05  ? 61  THR A CA  1 
ATOM   8592  C  C   . THR D 1 114 ? 148.714 126.525 112.971 1.00 34.34  ? 61  THR A C   1 
ATOM   8593  O  O   . THR D 1 114 ? 149.621 126.859 113.734 1.00 39.65  ? 61  THR A O   1 
ATOM   8594  C  CB  . THR D 1 114 ? 146.371 126.947 113.746 1.00 30.93  ? 61  THR A CB  1 
ATOM   8595  O  OG1 . THR D 1 114 ? 145.263 126.358 114.430 1.00 38.66  ? 61  THR A OG1 1 
ATOM   8596  C  CG2 . THR D 1 114 ? 145.875 127.517 112.443 1.00 32.37  ? 61  THR A CG2 1 
ATOM   8597  N  N   . ILE D 1 115 ? 148.791 126.674 111.652 1.00 31.99  ? 62  ILE A N   1 
ATOM   8598  C  CA  . ILE D 1 115 ? 149.947 127.304 111.025 1.00 28.34  ? 62  ILE A CA  1 
ATOM   8599  C  C   . ILE D 1 115 ? 149.483 128.025 109.768 1.00 32.29  ? 62  ILE A C   1 
ATOM   8600  O  O   . ILE D 1 115 ? 148.575 127.566 109.076 1.00 36.86  ? 62  ILE A O   1 
ATOM   8601  C  CB  . ILE D 1 115 ? 151.050 126.263 110.733 1.00 27.86  ? 62  ILE A CB  1 
ATOM   8602  C  CG1 . ILE D 1 115 ? 152.357 126.938 110.353 1.00 28.23  ? 62  ILE A CG1 1 
ATOM   8603  C  CG2 . ILE D 1 115 ? 150.630 125.302 109.649 1.00 28.00  ? 62  ILE A CG2 1 
ATOM   8604  C  CD1 . ILE D 1 115 ? 153.509 126.002 110.345 1.00 26.63  ? 62  ILE A CD1 1 
ATOM   8605  N  N   . ASP D 1 116 ? 150.085 129.178 109.490 1.00 31.72  ? 63  ASP A N   1 
ATOM   8606  C  CA  . ASP D 1 116 ? 149.795 129.962 108.294 1.00 29.58  ? 63  ASP A CA  1 
ATOM   8607  C  C   . ASP D 1 116 ? 151.055 130.030 107.448 1.00 30.92  ? 63  ASP A C   1 
ATOM   8608  O  O   . ASP D 1 116 ? 152.100 130.473 107.929 1.00 35.46  ? 63  ASP A O   1 
ATOM   8609  C  CB  . ASP D 1 116 ? 149.317 131.366 108.654 1.00 33.12  ? 63  ASP A CB  1 
ATOM   8610  C  CG  . ASP D 1 116 ? 147.970 131.366 109.328 1.00 46.25  ? 63  ASP A CG  1 
ATOM   8611  O  OD1 . ASP D 1 116 ? 147.856 130.811 110.440 1.00 48.64  ? 63  ASP A OD1 1 
ATOM   8612  O  OD2 . ASP D 1 116 ? 147.020 131.926 108.747 1.00 51.48  ? 63  ASP A OD2 1 
ATOM   8613  N  N   . VAL D 1 117 ? 150.960 129.600 106.196 1.00 28.99  ? 64  VAL A N   1 
ATOM   8614  C  CA  . VAL D 1 117 ? 152.146 129.399 105.378 1.00 25.89  ? 64  VAL A CA  1 
ATOM   8615  C  C   . VAL D 1 117 ? 151.959 129.984 103.988 1.00 27.23  ? 64  VAL A C   1 
ATOM   8616  O  O   . VAL D 1 117 ? 150.843 130.081 103.470 1.00 31.91  ? 64  VAL A O   1 
ATOM   8617  C  CB  . VAL D 1 117 ? 152.516 127.902 105.269 1.00 27.67  ? 64  VAL A CB  1 
ATOM   8618  C  CG1 . VAL D 1 117 ? 152.870 127.335 106.623 1.00 28.90  ? 64  VAL A CG1 1 
ATOM   8619  C  CG2 . VAL D 1 117 ? 151.380 127.116 104.658 1.00 28.23  ? 64  VAL A CG2 1 
ATOM   8620  N  N   . PHE D 1 118 ? 153.076 130.395 103.399 1.00 29.29  ? 65  PHE A N   1 
ATOM   8621  C  CA  . PHE D 1 118 ? 153.227 130.496 101.954 1.00 25.68  ? 65  PHE A CA  1 
ATOM   8622  C  C   . PHE D 1 118 ? 153.856 129.193 101.488 1.00 30.17  ? 65  PHE A C   1 
ATOM   8623  O  O   . PHE D 1 118 ? 155.007 128.899 101.825 1.00 36.89  ? 65  PHE A O   1 
ATOM   8624  C  CB  . PHE D 1 118 ? 154.104 131.679 101.561 1.00 27.77  ? 65  PHE A CB  1 
ATOM   8625  C  CG  . PHE D 1 118 ? 153.436 133.003 101.689 1.00 31.67  ? 65  PHE A CG  1 
ATOM   8626  C  CD1 . PHE D 1 118 ? 152.064 133.107 101.676 1.00 31.09  ? 65  PHE A CD1 1 
ATOM   8627  C  CD2 . PHE D 1 118 ? 154.182 134.151 101.820 1.00 30.53  ? 65  PHE A CD2 1 
ATOM   8628  C  CE1 . PHE D 1 118 ? 151.454 134.329 101.792 1.00 26.73  ? 65  PHE A CE1 1 
ATOM   8629  C  CE2 . PHE D 1 118 ? 153.572 135.368 101.940 1.00 25.44  ? 65  PHE A CE2 1 
ATOM   8630  C  CZ  . PHE D 1 118 ? 152.208 135.455 101.928 1.00 24.90  ? 65  PHE A CZ  1 
ATOM   8631  N  N   . PHE D 1 119 ? 153.103 128.416 100.724 1.00 31.06  ? 66  PHE A N   1 
ATOM   8632  C  CA  . PHE D 1 119 ? 153.516 127.105 100.252 1.00 28.82  ? 66  PHE A CA  1 
ATOM   8633  C  C   . PHE D 1 119 ? 153.925 127.234 98.790  1.00 31.53  ? 66  PHE A C   1 
ATOM   8634  O  O   . PHE D 1 119 ? 153.105 127.626 97.953  1.00 34.04  ? 66  PHE A O   1 
ATOM   8635  C  CB  . PHE D 1 119 ? 152.361 126.121 100.433 1.00 26.03  ? 66  PHE A CB  1 
ATOM   8636  C  CG  . PHE D 1 119 ? 152.724 124.698 100.194 1.00 28.93  ? 66  PHE A CG  1 
ATOM   8637  C  CD1 . PHE D 1 119 ? 153.522 124.018 101.083 1.00 31.56  ? 66  PHE A CD1 1 
ATOM   8638  C  CD2 . PHE D 1 119 ? 152.243 124.027 99.094  1.00 28.21  ? 66  PHE A CD2 1 
ATOM   8639  C  CE1 . PHE D 1 119 ? 153.849 122.709 100.864 1.00 30.08  ? 66  PHE A CE1 1 
ATOM   8640  C  CE2 . PHE D 1 119 ? 152.570 122.717 98.878  1.00 29.30  ? 66  PHE A CE2 1 
ATOM   8641  C  CZ  . PHE D 1 119 ? 153.375 122.059 99.763  1.00 31.83  ? 66  PHE A CZ  1 
ATOM   8642  N  N   . ARG D 1 120 ? 155.189 126.934 98.486  1.00 31.50  ? 67  ARG A N   1 
ATOM   8643  C  CA  . ARG D 1 120 ? 155.753 127.176 97.165  1.00 30.61  ? 67  ARG A CA  1 
ATOM   8644  C  C   . ARG D 1 120 ? 156.218 125.870 96.546  1.00 29.63  ? 67  ARG A C   1 
ATOM   8645  O  O   . ARG D 1 120 ? 156.950 125.107 97.181  1.00 38.87  ? 67  ARG A O   1 
ATOM   8646  C  CB  . ARG D 1 120 ? 156.931 128.147 97.232  1.00 32.45  ? 67  ARG A CB  1 
ATOM   8647  C  CG  . ARG D 1 120 ? 156.698 129.368 98.077  1.00 35.01  ? 67  ARG A CG  1 
ATOM   8648  C  CD  . ARG D 1 120 ? 157.793 130.373 97.842  1.00 40.77  ? 67  ARG A CD  1 
ATOM   8649  N  NE  . ARG D 1 120 ? 157.671 131.544 98.697  1.00 46.14  ? 67  ARG A NE  1 
ATOM   8650  C  CZ  . ARG D 1 120 ? 158.467 131.805 99.722  1.00 47.54  ? 67  ARG A CZ  1 
ATOM   8651  N  NH1 . ARG D 1 120 ? 159.450 130.988 100.057 1.00 43.59  ? 67  ARG A NH1 1 
ATOM   8652  N  NH2 . ARG D 1 120 ? 158.275 132.915 100.425 1.00 49.50  ? 67  ARG A NH2 1 
ATOM   8653  N  N   . GLN D 1 121 ? 155.814 125.636 95.300  1.00 26.21  ? 68  GLN A N   1 
ATOM   8654  C  CA  . GLN D 1 121 ? 156.207 124.468 94.534  1.00 28.55  ? 68  GLN A CA  1 
ATOM   8655  C  C   . GLN D 1 121 ? 156.734 124.922 93.183  1.00 32.21  ? 68  GLN A C   1 
ATOM   8656  O  O   . GLN D 1 121 ? 156.330 125.959 92.661  1.00 35.24  ? 68  GLN A O   1 
ATOM   8657  C  CB  . GLN D 1 121 ? 155.033 123.507 94.346  1.00 29.47  ? 68  GLN A CB  1 
ATOM   8658  C  CG  . GLN D 1 121 ? 154.464 122.999 95.649  1.00 31.88  ? 68  GLN A CG  1 
ATOM   8659  C  CD  . GLN D 1 121 ? 153.205 122.192 95.476  1.00 33.33  ? 68  GLN A CD  1 
ATOM   8660  O  OE1 . GLN D 1 121 ? 153.240 120.969 95.473  1.00 40.88  ? 68  GLN A OE1 1 
ATOM   8661  N  NE2 . GLN D 1 121 ? 152.081 122.871 95.358  1.00 32.12  ? 68  GLN A NE2 1 
ATOM   8662  N  N   . SER D 1 122 ? 157.660 124.150 92.633  1.00 33.16  ? 69  SER A N   1 
ATOM   8663  C  CA  . SER D 1 122 ? 158.280 124.493 91.362  1.00 31.25  ? 69  SER A CA  1 
ATOM   8664  C  C   . SER D 1 122 ? 158.566 123.217 90.593  1.00 34.39  ? 69  SER A C   1 
ATOM   8665  O  O   . SER D 1 122 ? 159.100 122.262 91.160  1.00 40.88  ? 69  SER A O   1 
ATOM   8666  C  CB  . SER D 1 122 ? 159.571 125.283 91.579  1.00 36.84  ? 69  SER A CB  1 
ATOM   8667  O  OG  . SER D 1 122 ? 160.233 125.522 90.354  1.00 40.40  ? 69  SER A OG  1 
ATOM   8668  N  N   . TRP D 1 123 ? 158.213 123.198 89.313  1.00 35.76  ? 70  TRP A N   1 
ATOM   8669  C  CA  . TRP D 1 123 ? 158.444 122.001 88.511  1.00 38.04  ? 70  TRP A CA  1 
ATOM   8670  C  C   . TRP D 1 123 ? 158.712 122.401 87.069  1.00 39.70  ? 70  TRP A C   1 
ATOM   8671  O  O   . TRP D 1 123 ? 158.704 123.579 86.718  1.00 43.21  ? 70  TRP A O   1 
ATOM   8672  C  CB  . TRP D 1 123 ? 157.278 121.008 88.627  1.00 35.49  ? 70  TRP A CB  1 
ATOM   8673  C  CG  . TRP D 1 123 ? 155.985 121.454 88.034  1.00 35.01  ? 70  TRP A CG  1 
ATOM   8674  C  CD1 . TRP D 1 123 ? 155.508 121.160 86.795  1.00 35.46  ? 70  TRP A CD1 1 
ATOM   8675  C  CD2 . TRP D 1 123 ? 154.988 122.255 88.666  1.00 35.59  ? 70  TRP A CD2 1 
ATOM   8676  N  NE1 . TRP D 1 123 ? 154.282 121.738 86.609  1.00 39.94  ? 70  TRP A NE1 1 
ATOM   8677  C  CE2 . TRP D 1 123 ? 153.941 122.420 87.746  1.00 38.22  ? 70  TRP A CE2 1 
ATOM   8678  C  CE3 . TRP D 1 123 ? 154.883 122.857 89.918  1.00 35.00  ? 70  TRP A CE3 1 
ATOM   8679  C  CZ2 . TRP D 1 123 ? 152.807 123.161 88.038  1.00 36.71  ? 70  TRP A CZ2 1 
ATOM   8680  C  CZ3 . TRP D 1 123 ? 153.758 123.590 90.204  1.00 36.28  ? 70  TRP A CZ3 1 
ATOM   8681  C  CH2 . TRP D 1 123 ? 152.736 123.739 89.271  1.00 34.34  ? 70  TRP A CH2 1 
ATOM   8682  N  N   . LYS D 1 124 ? 158.993 121.404 86.239  1.00 42.88  ? 71  LYS A N   1 
ATOM   8683  C  CA  . LYS D 1 124 ? 159.397 121.609 84.856  1.00 45.84  ? 71  LYS A CA  1 
ATOM   8684  C  C   . LYS D 1 124 ? 158.387 120.946 83.938  1.00 47.94  ? 71  LYS A C   1 
ATOM   8685  O  O   . LYS D 1 124 ? 158.050 119.774 84.123  1.00 53.92  ? 71  LYS A O   1 
ATOM   8686  C  CB  . LYS D 1 124 ? 160.795 121.044 84.604  1.00 50.21  ? 71  LYS A CB  1 
ATOM   8687  C  CG  . LYS D 1 124 ? 161.158 120.865 83.139  1.00 56.43  ? 71  LYS A CG  1 
ATOM   8688  C  CD  . LYS D 1 124 ? 161.449 122.186 82.463  1.00 56.60  ? 71  LYS A CD  1 
ATOM   8689  C  CE  . LYS D 1 124 ? 162.676 122.844 83.055  1.00 61.66  ? 71  LYS A CE  1 
ATOM   8690  N  NZ  . LYS D 1 124 ? 163.877 121.972 82.959  1.00 71.54  ? 71  LYS A NZ  1 
ATOM   8691  N  N   . ASP D 1 125 ? 157.911 121.696 82.952  1.00 50.13  ? 72  ASP A N   1 
ATOM   8692  C  CA  . ASP D 1 125 ? 156.938 121.213 81.985  1.00 51.60  ? 72  ASP A CA  1 
ATOM   8693  C  C   . ASP D 1 125 ? 157.387 121.666 80.606  1.00 57.46  ? 72  ASP A C   1 
ATOM   8694  O  O   . ASP D 1 125 ? 157.444 122.869 80.338  1.00 61.21  ? 72  ASP A O   1 
ATOM   8695  C  CB  . ASP D 1 125 ? 155.544 121.745 82.315  1.00 48.78  ? 72  ASP A CB  1 
ATOM   8696  C  CG  . ASP D 1 125 ? 154.457 121.054 81.543  1.00 53.38  ? 72  ASP A CG  1 
ATOM   8697  O  OD1 . ASP D 1 125 ? 154.774 120.299 80.606  1.00 56.76  ? 72  ASP A OD1 1 
ATOM   8698  O  OD2 . ASP D 1 125 ? 153.277 121.264 81.879  1.00 53.93  ? 72  ASP A OD2 1 
ATOM   8699  N  N   . GLU D 1 126 ? 157.710 120.710 79.737  1.00 59.15  ? 73  GLU A N   1 
ATOM   8700  C  CA  . GLU D 1 126 ? 158.265 121.037 78.431  1.00 62.55  ? 73  GLU A CA  1 
ATOM   8701  C  C   . GLU D 1 126 ? 157.206 121.429 77.412  1.00 63.32  ? 73  GLU A C   1 
ATOM   8702  O  O   . GLU D 1 126 ? 157.559 121.808 76.292  1.00 67.43  ? 73  GLU A O   1 
ATOM   8703  C  CB  . GLU D 1 126 ? 159.080 119.861 77.893  1.00 66.33  ? 73  GLU A CB  1 
ATOM   8704  C  CG  . GLU D 1 126 ? 160.195 119.383 78.811  1.00 73.43  ? 73  GLU A CG  1 
ATOM   8705  C  CD  . GLU D 1 126 ? 161.399 120.311 78.833  1.00 87.85  ? 73  GLU A CD  1 
ATOM   8706  O  OE1 . GLU D 1 126 ? 161.246 121.489 79.217  1.00 80.71  ? 73  GLU A OE1 1 
ATOM   8707  O  OE2 . GLU D 1 126 ? 162.505 119.857 78.470  1.00 100.35 ? 73  GLU A OE2 1 
ATOM   8708  N  N   . ARG D 1 127 ? 155.928 121.333 77.759  1.00 56.56  ? 74  ARG A N   1 
ATOM   8709  C  CA  . ARG D 1 127 ? 154.862 121.782 76.878  1.00 56.07  ? 74  ARG A CA  1 
ATOM   8710  C  C   . ARG D 1 127 ? 154.621 123.279 76.966  1.00 56.97  ? 74  ARG A C   1 
ATOM   8711  O  O   . ARG D 1 127 ? 153.801 123.803 76.206  1.00 54.91  ? 74  ARG A O   1 
ATOM   8712  C  CB  . ARG D 1 127 ? 153.565 121.041 77.202  1.00 52.32  ? 74  ARG A CB  1 
ATOM   8713  C  CG  . ARG D 1 127 ? 153.611 119.551 76.951  1.00 50.97  ? 74  ARG A CG  1 
ATOM   8714  C  CD  . ARG D 1 127 ? 152.346 118.887 77.445  1.00 53.62  ? 74  ARG A CD  1 
ATOM   8715  N  NE  . ARG D 1 127 ? 152.272 118.865 78.901  1.00 53.68  ? 74  ARG A NE  1 
ATOM   8716  C  CZ  . ARG D 1 127 ? 151.272 118.336 79.591  1.00 50.47  ? 74  ARG A CZ  1 
ATOM   8717  N  NH1 . ARG D 1 127 ? 150.236 117.781 78.989  1.00 51.09  ? 74  ARG A NH1 1 
ATOM   8718  N  NH2 . ARG D 1 127 ? 151.309 118.372 80.918  1.00 45.89  ? 74  ARG A NH2 1 
ATOM   8719  N  N   . LEU D 1 128 ? 155.305 123.975 77.874  1.00 57.86  ? 75  LEU A N   1 
ATOM   8720  C  CA  . LEU D 1 128 ? 155.072 125.394 78.115  1.00 58.85  ? 75  LEU A CA  1 
ATOM   8721  C  C   . LEU D 1 128 ? 156.281 126.252 77.758  1.00 60.92  ? 75  LEU A C   1 
ATOM   8722  O  O   . LEU D 1 128 ? 156.422 127.359 78.281  1.00 64.76  ? 75  LEU A O   1 
ATOM   8723  C  CB  . LEU D 1 128 ? 154.670 125.622 79.572  1.00 49.42  ? 75  LEU A CB  1 
ATOM   8724  C  CG  . LEU D 1 128 ? 153.380 124.924 80.001  1.00 45.76  ? 75  LEU A CG  1 
ATOM   8725  C  CD1 . LEU D 1 128 ? 153.051 125.232 81.433  1.00 41.78  ? 75  LEU A CD1 1 
ATOM   8726  C  CD2 . LEU D 1 128 ? 152.241 125.335 79.110  1.00 51.99  ? 75  LEU A CD2 1 
ATOM   8727  N  N   . LYS D 1 129 ? 157.159 125.765 76.887  1.00 60.96  ? 76  LYS A N   1 
ATOM   8728  C  CA  . LYS D 1 129 ? 158.261 126.583 76.406  1.00 60.72  ? 76  LYS A CA  1 
ATOM   8729  C  C   . LYS D 1 129 ? 157.739 127.688 75.499  1.00 65.99  ? 76  LYS A C   1 
ATOM   8730  O  O   . LYS D 1 129 ? 156.825 127.476 74.700  1.00 72.06  ? 76  LYS A O   1 
ATOM   8731  C  CB  . LYS D 1 129 ? 159.270 125.730 75.643  1.00 61.35  ? 76  LYS A CB  1 
ATOM   8732  C  CG  . LYS D 1 129 ? 159.950 124.666 76.467  1.00 65.37  ? 76  LYS A CG  1 
ATOM   8733  C  CD  . LYS D 1 129 ? 160.865 123.835 75.592  1.00 74.13  ? 76  LYS A CD  1 
ATOM   8734  C  CE  . LYS D 1 129 ? 161.606 122.786 76.397  1.00 78.97  ? 76  LYS A CE  1 
ATOM   8735  N  NZ  . LYS D 1 129 ? 162.406 123.389 77.500  1.00 80.12  ? 76  LYS A NZ  1 
ATOM   8736  N  N   . PHE D 1 130 ? 158.335 128.871 75.611  1.00 63.78  ? 77  PHE A N   1 
ATOM   8737  C  CA  . PHE D 1 130 ? 157.943 129.979 74.755  1.00 65.38  ? 77  PHE A CA  1 
ATOM   8738  C  C   . PHE D 1 130 ? 159.144 130.879 74.516  1.00 67.48  ? 77  PHE A C   1 
ATOM   8739  O  O   . PHE D 1 130 ? 160.128 130.846 75.256  1.00 68.62  ? 77  PHE A O   1 
ATOM   8740  C  CB  . PHE D 1 130 ? 156.784 130.780 75.361  1.00 60.08  ? 77  PHE A CB  1 
ATOM   8741  C  CG  . PHE D 1 130 ? 157.143 131.514 76.615  1.00 62.35  ? 77  PHE A CG  1 
ATOM   8742  C  CD1 . PHE D 1 130 ? 157.030 130.901 77.844  1.00 60.65  ? 77  PHE A CD1 1 
ATOM   8743  C  CD2 . PHE D 1 130 ? 157.581 132.820 76.567  1.00 64.43  ? 77  PHE A CD2 1 
ATOM   8744  C  CE1 . PHE D 1 130 ? 157.356 131.573 78.996  1.00 56.84  ? 77  PHE A CE1 1 
ATOM   8745  C  CE2 . PHE D 1 130 ? 157.910 133.492 77.715  1.00 61.77  ? 77  PHE A CE2 1 
ATOM   8746  C  CZ  . PHE D 1 130 ? 157.795 132.868 78.932  1.00 57.25  ? 77  PHE A CZ  1 
ATOM   8747  N  N   . LYS D 1 131 ? 159.052 131.682 73.461  1.00 68.25  ? 78  LYS A N   1 
ATOM   8748  C  CA  . LYS D 1 131 ? 160.060 132.686 73.151  1.00 72.25  ? 78  LYS A CA  1 
ATOM   8749  C  C   . LYS D 1 131 ? 159.348 133.991 72.841  1.00 72.73  ? 78  LYS A C   1 
ATOM   8750  O  O   . LYS D 1 131 ? 158.526 134.045 71.922  1.00 70.65  ? 78  LYS A O   1 
ATOM   8751  C  CB  . LYS D 1 131 ? 160.934 132.254 71.972  1.00 77.13  ? 78  LYS A CB  1 
ATOM   8752  C  CG  . LYS D 1 131 ? 162.124 133.160 71.726  1.00 82.82  ? 78  LYS A CG  1 
ATOM   8753  C  CD  . LYS D 1 131 ? 162.945 132.680 70.543  1.00 93.96  ? 78  LYS A CD  1 
ATOM   8754  C  CE  . LYS D 1 131 ? 164.112 133.611 70.266  1.00 100.06 ? 78  LYS A CE  1 
ATOM   8755  N  NZ  . LYS D 1 131 ? 164.906 133.169 69.088  1.00 100.03 ? 78  LYS A NZ  1 
ATOM   8756  N  N   . GLY D 1 132 ? 159.660 135.034 73.603  1.00 73.94  ? 79  GLY A N   1 
ATOM   8757  C  CA  . GLY D 1 132 ? 158.991 136.302 73.451  1.00 73.03  ? 79  GLY A CA  1 
ATOM   8758  C  C   . GLY D 1 132 ? 159.762 137.452 74.062  1.00 76.08  ? 79  GLY A C   1 
ATOM   8759  O  O   . GLY D 1 132 ? 160.914 137.310 74.480  1.00 78.15  ? 79  GLY A O   1 
ATOM   8760  N  N   . PRO D 1 133 ? 159.137 138.630 74.100  1.00 78.73  ? 80  PRO A N   1 
ATOM   8761  C  CA  . PRO D 1 133 ? 159.816 139.801 74.676  1.00 83.07  ? 80  PRO A CA  1 
ATOM   8762  C  C   . PRO D 1 133 ? 160.189 139.645 76.140  1.00 79.78  ? 80  PRO A C   1 
ATOM   8763  O  O   . PRO D 1 133 ? 161.225 140.176 76.559  1.00 76.16  ? 80  PRO A O   1 
ATOM   8764  C  CB  . PRO D 1 133 ? 158.797 140.932 74.468  1.00 81.77  ? 80  PRO A CB  1 
ATOM   8765  C  CG  . PRO D 1 133 ? 157.500 140.255 74.201  1.00 75.82  ? 80  PRO A CG  1 
ATOM   8766  C  CD  . PRO D 1 133 ? 157.829 138.975 73.523  1.00 75.50  ? 80  PRO A CD  1 
ATOM   8767  N  N   . MET D 1 134 ? 159.391 138.938 76.933  1.00 81.15  ? 81  MET A N   1 
ATOM   8768  C  CA  . MET D 1 134 ? 159.653 138.778 78.356  1.00 77.00  ? 81  MET A CA  1 
ATOM   8769  C  C   . MET D 1 134 ? 160.189 137.384 78.644  1.00 74.45  ? 81  MET A C   1 
ATOM   8770  O  O   . MET D 1 134 ? 159.719 136.396 78.076  1.00 74.83  ? 81  MET A O   1 
ATOM   8771  C  CB  . MET D 1 134 ? 158.391 139.022 79.183  1.00 78.51  ? 81  MET A CB  1 
ATOM   8772  C  CG  . MET D 1 134 ? 157.803 140.409 79.034  1.00 87.29  ? 81  MET A CG  1 
ATOM   8773  S  SD  . MET D 1 134 ? 156.486 140.723 80.221  1.00 103.61 ? 81  MET A SD  1 
ATOM   8774  C  CE  . MET D 1 134 ? 157.438 140.886 81.724  1.00 84.84  ? 81  MET A CE  1 
ATOM   8775  N  N   . THR D 1 135 ? 161.184 137.314 79.527  1.00 74.41  ? 82  THR A N   1 
ATOM   8776  C  CA  . THR D 1 135 ? 161.739 136.028 79.926  1.00 72.33  ? 82  THR A CA  1 
ATOM   8777  C  C   . THR D 1 135 ? 160.807 135.267 80.857  1.00 69.65  ? 82  THR A C   1 
ATOM   8778  O  O   . THR D 1 135 ? 160.741 134.037 80.789  1.00 68.99  ? 82  THR A O   1 
ATOM   8779  C  CB  . THR D 1 135 ? 163.092 136.226 80.603  1.00 70.73  ? 82  THR A CB  1 
ATOM   8780  O  OG1 . THR D 1 135 ? 163.885 137.130 79.826  1.00 78.35  ? 82  THR A OG1 1 
ATOM   8781  C  CG2 . THR D 1 135 ? 163.820 134.905 80.711  1.00 70.29  ? 82  THR A CG2 1 
ATOM   8782  N  N   . VAL D 1 136 ? 160.091 135.969 81.730  1.00 67.28  ? 83  VAL A N   1 
ATOM   8783  C  CA  . VAL D 1 136 ? 159.179 135.354 82.683  1.00 58.80  ? 83  VAL A CA  1 
ATOM   8784  C  C   . VAL D 1 136 ? 157.803 135.968 82.492  1.00 62.14  ? 83  VAL A C   1 
ATOM   8785  O  O   . VAL D 1 136 ? 157.671 137.193 82.426  1.00 69.17  ? 83  VAL A O   1 
ATOM   8786  C  CB  . VAL D 1 136 ? 159.652 135.546 84.136  1.00 52.99  ? 83  VAL A CB  1 
ATOM   8787  C  CG1 . VAL D 1 136 ? 158.710 134.853 85.096  1.00 49.36  ? 83  VAL A CG1 1 
ATOM   8788  C  CG2 . VAL D 1 136 ? 161.054 135.016 84.306  1.00 59.23  ? 83  VAL A CG2 1 
ATOM   8789  N  N   . LEU D 1 137 ? 156.784 135.121 82.398  1.00 58.31  ? 84  LEU A N   1 
ATOM   8790  C  CA  . LEU D 1 137 ? 155.398 135.562 82.418  1.00 51.25  ? 84  LEU A CA  1 
ATOM   8791  C  C   . LEU D 1 137 ? 154.864 135.373 83.829  1.00 51.33  ? 84  LEU A C   1 
ATOM   8792  O  O   . LEU D 1 137 ? 154.813 134.245 84.329  1.00 53.85  ? 84  LEU A O   1 
ATOM   8793  C  CB  . LEU D 1 137 ? 154.548 134.786 81.414  1.00 46.76  ? 84  LEU A CB  1 
ATOM   8794  C  CG  . LEU D 1 137 ? 154.926 134.837 79.935  1.00 50.49  ? 84  LEU A CG  1 
ATOM   8795  C  CD1 . LEU D 1 137 ? 153.914 134.066 79.123  1.00 47.31  ? 84  LEU A CD1 1 
ATOM   8796  C  CD2 . LEU D 1 137 ? 155.014 136.259 79.439  1.00 60.65  ? 84  LEU A CD2 1 
ATOM   8797  N  N   . ARG D 1 138 ? 154.489 136.475 84.471  1.00 52.30  ? 85  ARG A N   1 
ATOM   8798  C  CA  . ARG D 1 138 ? 153.884 136.461 85.802  1.00 51.53  ? 85  ARG A CA  1 
ATOM   8799  C  C   . ARG D 1 138 ? 152.374 136.515 85.613  1.00 51.43  ? 85  ARG A C   1 
ATOM   8800  O  O   . ARG D 1 138 ? 151.783 137.590 85.534  1.00 53.74  ? 85  ARG A O   1 
ATOM   8801  C  CB  . ARG D 1 138 ? 154.383 137.632 86.638  1.00 50.59  ? 85  ARG A CB  1 
ATOM   8802  C  CG  . ARG D 1 138 ? 155.885 137.693 86.791  1.00 55.05  ? 85  ARG A CG  1 
ATOM   8803  C  CD  . ARG D 1 138 ? 156.311 138.885 87.630  1.00 57.18  ? 85  ARG A CD  1 
ATOM   8804  N  NE  . ARG D 1 138 ? 156.355 140.118 86.855  1.00 66.44  ? 85  ARG A NE  1 
ATOM   8805  C  CZ  . ARG D 1 138 ? 157.432 140.568 86.228  1.00 72.18  ? 85  ARG A CZ  1 
ATOM   8806  N  NH1 . ARG D 1 138 ? 158.577 139.907 86.261  1.00 69.15  ? 85  ARG A NH1 1 
ATOM   8807  N  NH2 . ARG D 1 138 ? 157.360 141.709 85.551  1.00 72.97  ? 85  ARG A NH2 1 
ATOM   8808  N  N   . LEU D 1 139 ? 151.740 135.349 85.555  1.00 48.37  ? 86  LEU A N   1 
ATOM   8809  C  CA  . LEU D 1 139 ? 150.356 135.298 85.118  1.00 46.63  ? 86  LEU A CA  1 
ATOM   8810  C  C   . LEU D 1 139 ? 149.389 135.353 86.292  1.00 54.73  ? 86  LEU A C   1 
ATOM   8811  O  O   . LEU D 1 139 ? 149.754 135.148 87.451  1.00 57.79  ? 86  LEU A O   1 
ATOM   8812  C  CB  . LEU D 1 139 ? 150.100 134.036 84.301  1.00 46.23  ? 86  LEU A CB  1 
ATOM   8813  C  CG  . LEU D 1 139 ? 150.733 134.046 82.917  1.00 48.52  ? 86  LEU A CG  1 
ATOM   8814  C  CD1 . LEU D 1 139 ? 150.544 132.711 82.255  1.00 50.75  ? 86  LEU A CD1 1 
ATOM   8815  C  CD2 . LEU D 1 139 ? 150.116 135.141 82.080  1.00 48.43  ? 86  LEU A CD2 1 
ATOM   8816  N  N   . ASN D 1 140 ? 148.137 135.650 85.965  1.00 59.69  ? 87  ASN A N   1 
ATOM   8817  C  CA  . ASN D 1 140 ? 147.050 135.562 86.925  1.00 61.98  ? 87  ASN A CA  1 
ATOM   8818  C  C   . ASN D 1 140 ? 146.844 134.109 87.337  1.00 56.82  ? 87  ASN A C   1 
ATOM   8819  O  O   . ASN D 1 140 ? 147.093 133.183 86.563  1.00 60.38  ? 87  ASN A O   1 
ATOM   8820  C  CB  . ASN D 1 140 ? 145.773 136.134 86.310  1.00 57.18  ? 87  ASN A CB  1 
ATOM   8821  C  CG  . ASN D 1 140 ? 144.742 136.503 87.343  1.00 61.43  ? 87  ASN A CG  1 
ATOM   8822  O  OD1 . ASN D 1 140 ? 143.647 135.949 87.366  1.00 62.44  ? 87  ASN A OD1 1 
ATOM   8823  N  ND2 . ASN D 1 140 ? 145.085 137.448 88.209  1.00 64.91  ? 87  ASN A ND2 1 
ATOM   8824  N  N   . ASN D 1 141 ? 146.390 133.910 88.576  1.00 50.04  ? 88  ASN A N   1 
ATOM   8825  C  CA  . ASN D 1 141 ? 146.210 132.550 89.074  1.00 54.31  ? 88  ASN A CA  1 
ATOM   8826  C  C   . ASN D 1 141 ? 145.147 131.784 88.298  1.00 56.13  ? 88  ASN A C   1 
ATOM   8827  O  O   . ASN D 1 141 ? 145.086 130.556 88.402  1.00 56.53  ? 88  ASN A O   1 
ATOM   8828  C  CB  . ASN D 1 141 ? 145.857 132.568 90.557  1.00 50.76  ? 88  ASN A CB  1 
ATOM   8829  C  CG  . ASN D 1 141 ? 144.670 133.445 90.860  1.00 54.90  ? 88  ASN A CG  1 
ATOM   8830  O  OD1 . ASN D 1 141 ? 143.537 133.111 90.521  1.00 58.50  ? 88  ASN A OD1 1 
ATOM   8831  N  ND2 . ASN D 1 141 ? 144.920 134.571 91.515  1.00 49.81  ? 88  ASN A ND2 1 
ATOM   8832  N  N   . LEU D 1 142 ? 144.313 132.482 87.528  1.00 53.31  ? 89  LEU A N   1 
ATOM   8833  C  CA  . LEU D 1 142 ? 143.356 131.810 86.657  1.00 51.42  ? 89  LEU A CA  1 
ATOM   8834  C  C   . LEU D 1 142 ? 144.047 130.799 85.754  1.00 52.59  ? 89  LEU A C   1 
ATOM   8835  O  O   . LEU D 1 142 ? 143.574 129.669 85.595  1.00 57.54  ? 89  LEU A O   1 
ATOM   8836  C  CB  . LEU D 1 142 ? 142.614 132.851 85.824  1.00 50.63  ? 89  LEU A CB  1 
ATOM   8837  C  CG  . LEU D 1 142 ? 141.589 132.364 84.814  1.00 57.86  ? 89  LEU A CG  1 
ATOM   8838  C  CD1 . LEU D 1 142 ? 140.437 131.699 85.540  1.00 67.78  ? 89  LEU A CD1 1 
ATOM   8839  C  CD2 . LEU D 1 142 ? 141.106 133.530 83.981  1.00 54.80  ? 89  LEU A CD2 1 
ATOM   8840  N  N   . MET D 1 143 ? 145.187 131.182 85.177  1.00 51.28  ? 90  MET A N   1 
ATOM   8841  C  CA  . MET D 1 143 ? 145.933 130.273 84.315  1.00 49.37  ? 90  MET A CA  1 
ATOM   8842  C  C   . MET D 1 143 ? 146.276 128.972 85.029  1.00 50.54  ? 90  MET A C   1 
ATOM   8843  O  O   . MET D 1 143 ? 146.311 127.910 84.399  1.00 50.49  ? 90  MET A O   1 
ATOM   8844  C  CB  . MET D 1 143 ? 147.200 130.966 83.816  1.00 49.13  ? 90  MET A CB  1 
ATOM   8845  C  CG  . MET D 1 143 ? 148.135 130.087 83.007  1.00 57.81  ? 90  MET A CG  1 
ATOM   8846  S  SD  . MET D 1 143 ? 147.532 129.683 81.361  1.00 77.79  ? 90  MET A SD  1 
ATOM   8847  C  CE  . MET D 1 143 ? 147.345 131.318 80.674  1.00 56.53  ? 90  MET A CE  1 
ATOM   8848  N  N   . ALA D 1 144 ? 146.497 129.024 86.344  1.00 52.43  ? 91  ALA A N   1 
ATOM   8849  C  CA  . ALA D 1 144 ? 146.877 127.822 87.074  1.00 51.63  ? 91  ALA A CA  1 
ATOM   8850  C  C   . ALA D 1 144 ? 145.777 126.771 87.075  1.00 50.32  ? 91  ALA A C   1 
ATOM   8851  O  O   . ALA D 1 144 ? 146.061 125.597 87.327  1.00 50.09  ? 91  ALA A O   1 
ATOM   8852  C  CB  . ALA D 1 144 ? 147.266 128.174 88.508  1.00 50.17  ? 91  ALA A CB  1 
ATOM   8853  N  N   . SER D 1 145 ? 144.537 127.153 86.795  1.00 52.01  ? 92  SER A N   1 
ATOM   8854  C  CA  . SER D 1 145 ? 143.451 126.187 86.727  1.00 52.04  ? 92  SER A CA  1 
ATOM   8855  C  C   . SER D 1 145 ? 143.284 125.592 85.339  1.00 51.81  ? 92  SER A C   1 
ATOM   8856  O  O   . SER D 1 145 ? 142.333 124.841 85.114  1.00 53.30  ? 92  SER A O   1 
ATOM   8857  C  CB  . SER D 1 145 ? 142.137 126.826 87.179  1.00 53.38  ? 92  SER A CB  1 
ATOM   8858  O  OG  . SER D 1 145 ? 141.791 127.926 86.360  1.00 57.33  ? 92  SER A OG  1 
ATOM   8859  N  N   . LYS D 1 146 ? 144.170 125.920 84.402  1.00 48.89  ? 93  LYS A N   1 
ATOM   8860  C  CA  . LYS D 1 146 ? 144.097 125.390 83.051  1.00 47.30  ? 93  LYS A CA  1 
ATOM   8861  C  C   . LYS D 1 146 ? 145.301 124.543 82.672  1.00 51.51  ? 93  LYS A C   1 
ATOM   8862  O  O   . LYS D 1 146 ? 145.372 124.073 81.532  1.00 58.19  ? 93  LYS A O   1 
ATOM   8863  C  CB  . LYS D 1 146 ? 143.940 126.534 82.045  1.00 49.24  ? 93  LYS A CB  1 
ATOM   8864  C  CG  . LYS D 1 146 ? 142.777 127.443 82.355  1.00 55.11  ? 93  LYS A CG  1 
ATOM   8865  C  CD  . LYS D 1 146 ? 142.755 128.649 81.449  1.00 61.71  ? 93  LYS A CD  1 
ATOM   8866  C  CE  . LYS D 1 146 ? 141.601 129.564 81.807  1.00 67.34  ? 93  LYS A CE  1 
ATOM   8867  N  NZ  . LYS D 1 146 ? 141.565 130.776 80.943  1.00 78.42  ? 93  LYS A NZ  1 
ATOM   8868  N  N   . ILE D 1 147 ? 146.241 124.332 83.589  1.00 47.86  ? 94  ILE A N   1 
ATOM   8869  C  CA  . ILE D 1 147 ? 147.412 123.500 83.345  1.00 44.76  ? 94  ILE A CA  1 
ATOM   8870  C  C   . ILE D 1 147 ? 147.416 122.382 84.375  1.00 44.93  ? 94  ILE A C   1 
ATOM   8871  O  O   . ILE D 1 147 ? 146.500 122.282 85.196  1.00 51.10  ? 94  ILE A O   1 
ATOM   8872  C  CB  . ILE D 1 147 ? 148.713 124.318 83.421  1.00 47.31  ? 94  ILE A CB  1 
ATOM   8873  C  CG1 . ILE D 1 147 ? 148.791 125.046 84.761  1.00 49.46  ? 94  ILE A CG1 1 
ATOM   8874  C  CG2 . ILE D 1 147 ? 148.791 125.305 82.284  1.00 46.82  ? 94  ILE A CG2 1 
ATOM   8875  C  CD1 . ILE D 1 147 ? 150.105 125.700 85.022  1.00 42.14  ? 94  ILE A CD1 1 
ATOM   8876  N  N   . TRP D 1 148 ? 148.433 121.532 84.339  1.00 43.35  ? 95  TRP A N   1 
ATOM   8877  C  CA  . TRP D 1 148 ? 148.595 120.488 85.340  1.00 40.34  ? 95  TRP A CA  1 
ATOM   8878  C  C   . TRP D 1 148 ? 149.350 121.045 86.538  1.00 41.36  ? 95  TRP A C   1 
ATOM   8879  O  O   . TRP D 1 148 ? 150.376 121.708 86.377  1.00 47.23  ? 95  TRP A O   1 
ATOM   8880  C  CB  . TRP D 1 148 ? 149.338 119.289 84.753  1.00 38.73  ? 95  TRP A CB  1 
ATOM   8881  C  CG  . TRP D 1 148 ? 149.527 118.166 85.721  1.00 39.81  ? 95  TRP A CG  1 
ATOM   8882  C  CD1 . TRP D 1 148 ? 148.739 117.068 85.859  1.00 38.93  ? 95  TRP A CD1 1 
ATOM   8883  C  CD2 . TRP D 1 148 ? 150.578 118.030 86.687  1.00 40.87  ? 95  TRP A CD2 1 
ATOM   8884  N  NE1 . TRP D 1 148 ? 149.228 116.258 86.849  1.00 37.70  ? 95  TRP A NE1 1 
ATOM   8885  C  CE2 . TRP D 1 148 ? 150.358 116.826 87.372  1.00 39.95  ? 95  TRP A CE2 1 
ATOM   8886  C  CE3 . TRP D 1 148 ? 151.681 118.811 87.039  1.00 39.43  ? 95  TRP A CE3 1 
ATOM   8887  C  CZ2 . TRP D 1 148 ? 151.198 116.385 88.386  1.00 38.51  ? 95  TRP A CZ2 1 
ATOM   8888  C  CZ3 . TRP D 1 148 ? 152.511 118.370 88.043  1.00 33.58  ? 95  TRP A CZ3 1 
ATOM   8889  C  CH2 . TRP D 1 148 ? 152.268 117.171 88.705  1.00 34.03  ? 95  TRP A CH2 1 
ATOM   8890  N  N   . THR D 1 149 ? 148.839 120.777 87.734  1.00 41.82  ? 96  THR A N   1 
ATOM   8891  C  CA  . THR D 1 149 ? 149.483 121.155 88.980  1.00 39.19  ? 96  THR A CA  1 
ATOM   8892  C  C   . THR D 1 149 ? 149.524 119.952 89.910  1.00 38.53  ? 96  THR A C   1 
ATOM   8893  O  O   . THR D 1 149 ? 148.693 119.049 89.791  1.00 39.73  ? 96  THR A O   1 
ATOM   8894  C  CB  . THR D 1 149 ? 148.743 122.314 89.664  1.00 43.38  ? 96  THR A CB  1 
ATOM   8895  O  OG1 . THR D 1 149 ? 147.379 121.947 89.898  1.00 53.76  ? 96  THR A OG1 1 
ATOM   8896  C  CG2 . THR D 1 149 ? 148.785 123.555 88.798  1.00 39.02  ? 96  THR A CG2 1 
ATOM   8897  N  N   . PRO D 1 150 ? 150.491 119.898 90.824  1.00 39.33  ? 97  PRO A N   1 
ATOM   8898  C  CA  . PRO D 1 150 ? 150.560 118.765 91.752  1.00 39.38  ? 97  PRO A CA  1 
ATOM   8899  C  C   . PRO D 1 150 ? 149.361 118.713 92.681  1.00 41.57  ? 97  PRO A C   1 
ATOM   8900  O  O   . PRO D 1 150 ? 148.780 119.737 93.045  1.00 46.38  ? 97  PRO A O   1 
ATOM   8901  C  CB  . PRO D 1 150 ? 151.848 119.028 92.538  1.00 33.17  ? 97  PRO A CB  1 
ATOM   8902  C  CG  . PRO D 1 150 ? 152.604 119.994 91.743  1.00 36.35  ? 97  PRO A CG  1 
ATOM   8903  C  CD  . PRO D 1 150 ? 151.612 120.826 91.020  1.00 38.25  ? 97  PRO A CD  1 
ATOM   8904  N  N   . ASP D 1 151 ? 148.992 117.494 93.064  1.00 38.46  ? 98  ASP A N   1 
ATOM   8905  C  CA  . ASP D 1 151 ? 147.930 117.277 94.044  1.00 31.62  ? 98  ASP A CA  1 
ATOM   8906  C  C   . ASP D 1 151 ? 148.545 117.004 95.414  1.00 28.79  ? 98  ASP A C   1 
ATOM   8907  O  O   . ASP D 1 151 ? 148.489 115.906 95.958  1.00 32.56  ? 98  ASP A O   1 
ATOM   8908  C  CB  . ASP D 1 151 ? 147.021 116.142 93.596  1.00 37.70  ? 98  ASP A CB  1 
ATOM   8909  C  CG  . ASP D 1 151 ? 147.787 114.902 93.223  1.00 43.11  ? 98  ASP A CG  1 
ATOM   8910  O  OD1 . ASP D 1 151 ? 149.030 114.967 93.173  1.00 41.20  ? 98  ASP A OD1 1 
ATOM   8911  O  OD2 . ASP D 1 151 ? 147.148 113.861 92.988  1.00 48.00  ? 98  ASP A OD2 1 
ATOM   8912  N  N   . THR D 1 152 ? 149.144 118.049 95.967  1.00 27.72  ? 99  THR A N   1 
ATOM   8913  C  CA  . THR D 1 152 ? 149.794 117.962 97.263  1.00 27.52  ? 99  THR A CA  1 
ATOM   8914  C  C   . THR D 1 152 ? 148.778 118.131 98.381  1.00 29.77  ? 99  THR A C   1 
ATOM   8915  O  O   . THR D 1 152 ? 147.900 118.992 98.316  1.00 40.44  ? 99  THR A O   1 
ATOM   8916  C  CB  . THR D 1 152 ? 150.879 119.033 97.370  1.00 33.12  ? 99  THR A CB  1 
ATOM   8917  O  OG1 . THR D 1 152 ? 151.814 118.862 96.304  1.00 36.17  ? 99  THR A OG1 1 
ATOM   8918  C  CG2 . THR D 1 152 ? 151.613 118.939 98.683  1.00 31.28  ? 99  THR A CG2 1 
ATOM   8919  N  N   . PHE D 1 153 ? 148.894 117.295 99.407  1.00 27.98  ? 100 PHE A N   1 
ATOM   8920  C  CA  . PHE D 1 153 ? 148.021 117.364 100.566 1.00 25.61  ? 100 PHE A CA  1 
ATOM   8921  C  C   . PHE D 1 153 ? 148.833 117.064 101.815 1.00 27.75  ? 100 PHE A C   1 
ATOM   8922  O  O   . PHE D 1 153 ? 149.933 116.516 101.746 1.00 31.57  ? 100 PHE A O   1 
ATOM   8923  C  CB  . PHE D 1 153 ? 146.837 116.402 100.435 1.00 25.11  ? 100 PHE A CB  1 
ATOM   8924  C  CG  . PHE D 1 153 ? 147.138 114.993 100.847 1.00 26.58  ? 100 PHE A CG  1 
ATOM   8925  C  CD1 . PHE D 1 153 ? 148.051 114.227 100.159 1.00 27.36  ? 100 PHE A CD1 1 
ATOM   8926  C  CD2 . PHE D 1 153 ? 146.472 114.424 101.906 1.00 27.44  ? 100 PHE A CD2 1 
ATOM   8927  C  CE1 . PHE D 1 153 ? 148.307 112.932 100.543 1.00 26.16  ? 100 PHE A CE1 1 
ATOM   8928  C  CE2 . PHE D 1 153 ? 146.726 113.134 102.287 1.00 26.76  ? 100 PHE A CE2 1 
ATOM   8929  C  CZ  . PHE D 1 153 ? 147.639 112.389 101.609 1.00 26.51  ? 100 PHE A CZ  1 
ATOM   8930  N  N   . PHE D 1 154 ? 148.287 117.452 102.961 1.00 27.27  ? 101 PHE A N   1 
ATOM   8931  C  CA  . PHE D 1 154 ? 148.959 117.305 104.245 1.00 28.00  ? 101 PHE A CA  1 
ATOM   8932  C  C   . PHE D 1 154 ? 148.410 116.083 104.969 1.00 27.60  ? 101 PHE A C   1 
ATOM   8933  O  O   . PHE D 1 154 ? 147.211 116.012 105.251 1.00 28.98  ? 101 PHE A O   1 
ATOM   8934  C  CB  . PHE D 1 154 ? 148.792 118.573 105.079 1.00 27.30  ? 101 PHE A CB  1 
ATOM   8935  C  CG  . PHE D 1 154 ? 149.404 119.784 104.444 1.00 29.97  ? 101 PHE A CG  1 
ATOM   8936  C  CD1 . PHE D 1 154 ? 148.698 120.527 103.527 1.00 30.45  ? 101 PHE A CD1 1 
ATOM   8937  C  CD2 . PHE D 1 154 ? 150.696 120.163 104.743 1.00 31.30  ? 101 PHE A CD2 1 
ATOM   8938  C  CE1 . PHE D 1 154 ? 149.263 121.624 102.928 1.00 28.36  ? 101 PHE A CE1 1 
ATOM   8939  C  CE2 . PHE D 1 154 ? 151.259 121.267 104.148 1.00 28.75  ? 101 PHE A CE2 1 
ATOM   8940  C  CZ  . PHE D 1 154 ? 150.542 121.994 103.240 1.00 27.03  ? 101 PHE A CZ  1 
ATOM   8941  N  N   . HIS D 1 155 ? 149.294 115.133 105.283 1.00 28.75  ? 102 HIS A N   1 
ATOM   8942  C  CA  . HIS D 1 155 ? 148.850 113.821 105.741 1.00 28.47  ? 102 HIS A CA  1 
ATOM   8943  C  C   . HIS D 1 155 ? 148.175 113.896 107.100 1.00 32.00  ? 102 HIS A C   1 
ATOM   8944  O  O   . HIS D 1 155 ? 147.245 113.133 107.375 1.00 38.41  ? 102 HIS A O   1 
ATOM   8945  C  CB  . HIS D 1 155 ? 150.024 112.848 105.796 1.00 29.03  ? 102 HIS A CB  1 
ATOM   8946  C  CG  . HIS D 1 155 ? 150.600 112.518 104.459 1.00 32.44  ? 102 HIS A CG  1 
ATOM   8947  N  ND1 . HIS D 1 155 ? 151.346 111.384 104.234 1.00 39.17  ? 102 HIS A ND1 1 
ATOM   8948  C  CD2 . HIS D 1 155 ? 150.546 113.172 103.278 1.00 32.69  ? 102 HIS A CD2 1 
ATOM   8949  C  CE1 . HIS D 1 155 ? 151.725 111.351 102.971 1.00 42.03  ? 102 HIS A CE1 1 
ATOM   8950  N  NE2 . HIS D 1 155 ? 151.256 112.427 102.369 1.00 39.60  ? 102 HIS A NE2 1 
ATOM   8951  N  N   . ASN D 1 156 ? 148.644 114.778 107.976 1.00 28.78  ? 103 ASN A N   1 
ATOM   8952  C  CA  . ASN D 1 156 ? 148.039 114.937 109.288 1.00 27.89  ? 103 ASN A CA  1 
ATOM   8953  C  C   . ASN D 1 156 ? 147.180 116.187 109.384 1.00 32.90  ? 103 ASN A C   1 
ATOM   8954  O  O   . ASN D 1 156 ? 146.830 116.603 110.490 1.00 41.56  ? 103 ASN A O   1 
ATOM   8955  C  CB  . ASN D 1 156 ? 149.113 114.943 110.373 1.00 31.57  ? 103 ASN A CB  1 
ATOM   8956  C  CG  . ASN D 1 156 ? 150.063 116.095 110.245 1.00 32.45  ? 103 ASN A CG  1 
ATOM   8957  O  OD1 . ASN D 1 156 ? 150.350 116.555 109.147 1.00 32.93  ? 103 ASN A OD1 1 
ATOM   8958  N  ND2 . ASN D 1 156 ? 150.568 116.566 111.368 1.00 34.18  ? 103 ASN A ND2 1 
ATOM   8959  N  N   . GLY D 1 157 ? 146.831 116.792 108.254 1.00 29.69  ? 104 GLY A N   1 
ATOM   8960  C  CA  . GLY D 1 157 ? 145.980 117.967 108.288 1.00 30.19  ? 104 GLY A CA  1 
ATOM   8961  C  C   . GLY D 1 157 ? 144.567 117.612 108.713 1.00 31.55  ? 104 GLY A C   1 
ATOM   8962  O  O   . GLY D 1 157 ? 144.038 116.557 108.366 1.00 34.33  ? 104 GLY A O   1 
ATOM   8963  N  N   . LYS D 1 158 ? 143.950 118.511 109.476 1.00 36.59  ? 105 LYS A N   1 
ATOM   8964  C  CA  . LYS D 1 158 ? 142.600 118.293 109.984 1.00 38.35  ? 105 LYS A CA  1 
ATOM   8965  C  C   . LYS D 1 158 ? 141.553 119.043 109.168 1.00 40.39  ? 105 LYS A C   1 
ATOM   8966  O  O   . LYS D 1 158 ? 140.652 118.423 108.602 1.00 53.05  ? 105 LYS A O   1 
ATOM   8967  C  CB  . LYS D 1 158 ? 142.519 118.684 111.464 1.00 39.77  ? 105 LYS A CB  1 
ATOM   8968  C  CG  . LYS D 1 158 ? 143.191 117.685 112.381 1.00 41.90  ? 105 LYS A CG  1 
ATOM   8969  C  CD  . LYS D 1 158 ? 142.885 117.942 113.837 1.00 46.44  ? 105 LYS A CD  1 
ATOM   8970  C  CE  . LYS D 1 158 ? 141.478 117.517 114.186 1.00 63.60  ? 105 LYS A CE  1 
ATOM   8971  N  NZ  . LYS D 1 158 ? 141.148 117.791 115.610 1.00 65.76  ? 105 LYS A NZ  1 
ATOM   8972  N  N   . LYS D 1 159 ? 141.646 120.367 109.100 1.00 35.53  ? 106 LYS A N   1 
ATOM   8973  C  CA  . LYS D 1 159 ? 140.768 121.125 108.211 1.00 38.77  ? 106 LYS A CA  1 
ATOM   8974  C  C   . LYS D 1 159 ? 141.494 122.406 107.817 1.00 44.86  ? 106 LYS A C   1 
ATOM   8975  O  O   . LYS D 1 159 ? 141.467 123.390 108.559 1.00 48.95  ? 106 LYS A O   1 
ATOM   8976  C  CB  . LYS D 1 159 ? 139.428 121.427 108.860 1.00 42.94  ? 106 LYS A CB  1 
ATOM   8977  C  CG  . LYS D 1 159 ? 138.451 122.072 107.899 1.00 50.60  ? 106 LYS A CG  1 
ATOM   8978  C  CD  . LYS D 1 159 ? 137.042 122.067 108.447 1.00 63.95  ? 106 LYS A CD  1 
ATOM   8979  C  CE  . LYS D 1 159 ? 136.059 122.602 107.423 1.00 69.69  ? 106 LYS A CE  1 
ATOM   8980  N  NZ  . LYS D 1 159 ? 136.139 121.847 106.146 1.00 70.54  ? 106 LYS A NZ  1 
ATOM   8981  N  N   . SER D 1 160 ? 142.105 122.390 106.643 1.00 43.29  ? 107 SER A N   1 
ATOM   8982  C  CA  . SER D 1 160 ? 142.873 123.513 106.147 1.00 33.51  ? 107 SER A CA  1 
ATOM   8983  C  C   . SER D 1 160 ? 141.975 124.481 105.390 1.00 32.87  ? 107 SER A C   1 
ATOM   8984  O  O   . SER D 1 160 ? 140.826 124.180 105.068 1.00 40.01  ? 107 SER A O   1 
ATOM   8985  C  CB  . SER D 1 160 ? 144.001 123.018 105.248 1.00 36.35  ? 107 SER A CB  1 
ATOM   8986  O  OG  . SER D 1 160 ? 144.667 121.917 105.832 1.00 44.08  ? 107 SER A OG  1 
ATOM   8987  N  N   . VAL D 1 161 ? 142.512 125.664 105.109 1.00 34.12  ? 108 VAL A N   1 
ATOM   8988  C  CA  . VAL D 1 161 ? 141.802 126.703 104.375 1.00 32.34  ? 108 VAL A CA  1 
ATOM   8989  C  C   . VAL D 1 161 ? 142.715 127.246 103.289 1.00 32.54  ? 108 VAL A C   1 
ATOM   8990  O  O   . VAL D 1 161 ? 143.862 127.607 103.563 1.00 36.01  ? 108 VAL A O   1 
ATOM   8991  C  CB  . VAL D 1 161 ? 141.345 127.847 105.298 1.00 32.07  ? 108 VAL A CB  1 
ATOM   8992  C  CG1 . VAL D 1 161 ? 140.693 128.941 104.490 1.00 29.57  ? 108 VAL A CG1 1 
ATOM   8993  C  CG2 . VAL D 1 161 ? 140.394 127.332 106.352 1.00 36.72  ? 108 VAL A CG2 1 
ATOM   8994  N  N   . ALA D 1 162 ? 142.207 127.312 102.065 1.00 32.03  ? 109 ALA A N   1 
ATOM   8995  C  CA  . ALA D 1 162 ? 142.882 127.986 100.964 1.00 27.91  ? 109 ALA A CA  1 
ATOM   8996  C  C   . ALA D 1 162 ? 142.203 129.334 100.768 1.00 31.77  ? 109 ALA A C   1 
ATOM   8997  O  O   . ALA D 1 162 ? 141.057 129.396 100.320 1.00 43.34  ? 109 ALA A O   1 
ATOM   8998  C  CB  . ALA D 1 162 ? 142.829 127.144 99.694  1.00 30.19  ? 109 ALA A CB  1 
ATOM   8999  N  N   . HIS D 1 163 ? 142.907 130.407 101.110 1.00 27.16  ? 110 HIS A N   1 
ATOM   9000  C  CA  . HIS D 1 163 ? 142.275 131.710 101.254 1.00 30.35  ? 110 HIS A CA  1 
ATOM   9001  C  C   . HIS D 1 163 ? 141.831 132.277 99.911  1.00 35.62  ? 110 HIS A C   1 
ATOM   9002  O  O   . HIS D 1 163 ? 142.542 132.182 98.911  1.00 37.98  ? 110 HIS A O   1 
ATOM   9003  C  CB  . HIS D 1 163 ? 143.229 132.665 101.958 1.00 30.02  ? 110 HIS A CB  1 
ATOM   9004  C  CG  . HIS D 1 163 ? 143.494 132.289 103.380 1.00 30.69  ? 110 HIS A CG  1 
ATOM   9005  N  ND1 . HIS D 1 163 ? 142.726 132.752 104.423 1.00 34.17  ? 110 HIS A ND1 1 
ATOM   9006  C  CD2 . HIS D 1 163 ? 144.417 131.467 103.929 1.00 29.44  ? 110 HIS A CD2 1 
ATOM   9007  C  CE1 . HIS D 1 163 ? 143.176 132.247 105.556 1.00 31.12  ? 110 HIS A CE1 1 
ATOM   9008  N  NE2 . HIS D 1 163 ? 144.202 131.464 105.284 1.00 30.27  ? 110 HIS A NE2 1 
ATOM   9009  N  N   . ASN D 1 164 ? 140.640 132.885 99.904  1.00 37.06  ? 111 ASN A N   1 
ATOM   9010  C  CA  . ASN D 1 164 ? 139.968 133.296 98.677  1.00 39.29  ? 111 ASN A CA  1 
ATOM   9011  C  C   . ASN D 1 164 ? 139.558 134.764 98.694  1.00 42.59  ? 111 ASN A C   1 
ATOM   9012  O  O   . ASN D 1 164 ? 138.676 135.156 97.931  1.00 50.61  ? 111 ASN A O   1 
ATOM   9013  C  CB  . ASN D 1 164 ? 138.731 132.427 98.433  1.00 49.09  ? 111 ASN A CB  1 
ATOM   9014  C  CG  . ASN D 1 164 ? 138.701 131.846 97.048  1.00 58.36  ? 111 ASN A CG  1 
ATOM   9015  O  OD1 . ASN D 1 164 ? 139.716 131.840 96.359  1.00 59.73  ? 111 ASN A OD1 1 
ATOM   9016  N  ND2 . ASN D 1 164 ? 137.545 131.349 96.617  1.00 69.61  ? 111 ASN A ND2 1 
ATOM   9017  N  N   . MET D 1 165 ? 140.163 135.582 99.545  1.00 39.73  ? 112 MET A N   1 
ATOM   9018  C  CA  . MET D 1 165 ? 139.824 136.993 99.664  1.00 38.95  ? 112 MET A CA  1 
ATOM   9019  C  C   . MET D 1 165 ? 141.054 137.831 99.354  1.00 39.63  ? 112 MET A C   1 
ATOM   9020  O  O   . MET D 1 165 ? 142.120 137.596 99.928  1.00 41.14  ? 112 MET A O   1 
ATOM   9021  C  CB  . MET D 1 165 ? 139.305 137.303 101.070 1.00 37.62  ? 112 MET A CB  1 
ATOM   9022  C  CG  . MET D 1 165 ? 139.107 138.776 101.370 1.00 42.27  ? 112 MET A CG  1 
ATOM   9023  S  SD  . MET D 1 165 ? 137.612 139.456 100.649 1.00 54.56  ? 112 MET A SD  1 
ATOM   9024  C  CE  . MET D 1 165 ? 136.388 138.518 101.533 1.00 39.41  ? 112 MET A CE  1 
ATOM   9025  N  N   . THR D 1 166 ? 140.914 138.810 98.462  1.00 35.57  ? 113 THR A N   1 
ATOM   9026  C  CA  . THR D 1 166 ? 139.668 139.097 97.763  1.00 33.57  ? 113 THR A CA  1 
ATOM   9027  C  C   . THR D 1 166 ? 139.582 138.318 96.462  1.00 39.26  ? 113 THR A C   1 
ATOM   9028  O  O   . THR D 1 166 ? 138.545 138.278 95.812  1.00 44.75  ? 113 THR A O   1 
ATOM   9029  C  CB  . THR D 1 166 ? 139.532 140.589 97.461  1.00 33.92  ? 113 THR A CB  1 
ATOM   9030  O  OG1 . THR D 1 166 ? 140.384 140.931 96.367  1.00 39.72  ? 113 THR A OG1 1 
ATOM   9031  C  CG2 . THR D 1 166 ? 139.943 141.400 98.659  1.00 34.19  ? 113 THR A CG2 1 
ATOM   9032  N  N   . MET D 1 167 ? 140.692 137.702 96.097  1.00 38.90  ? 114 MET A N   1 
ATOM   9033  C  CA  . MET D 1 167 ? 140.827 136.797 94.969  1.00 38.35  ? 114 MET A CA  1 
ATOM   9034  C  C   . MET D 1 167 ? 141.570 135.573 95.472  1.00 42.58  ? 114 MET A C   1 
ATOM   9035  O  O   . MET D 1 167 ? 142.163 135.610 96.554  1.00 45.83  ? 114 MET A O   1 
ATOM   9036  C  CB  . MET D 1 167 ? 141.599 137.443 93.809  1.00 38.10  ? 114 MET A CB  1 
ATOM   9037  C  CG  . MET D 1 167 ? 141.022 138.744 93.297  1.00 50.74  ? 114 MET A CG  1 
ATOM   9038  S  SD  . MET D 1 167 ? 139.315 138.618 92.741  1.00 76.94  ? 114 MET A SD  1 
ATOM   9039  C  CE  . MET D 1 167 ? 139.508 137.583 91.301  1.00 51.67  ? 114 MET A CE  1 
ATOM   9040  N  N   . PRO D 1 168 ? 141.536 134.461 94.732  1.00 42.79  ? 115 PRO A N   1 
ATOM   9041  C  CA  . PRO D 1 168 ? 142.343 133.302 95.134  1.00 42.11  ? 115 PRO A CA  1 
ATOM   9042  C  C   . PRO D 1 168 ? 143.794 133.664 95.395  1.00 42.06  ? 115 PRO A C   1 
ATOM   9043  O  O   . PRO D 1 168 ? 144.493 134.134 94.496  1.00 43.93  ? 115 PRO A O   1 
ATOM   9044  C  CB  . PRO D 1 168 ? 142.210 132.359 93.937  1.00 37.15  ? 115 PRO A CB  1 
ATOM   9045  C  CG  . PRO D 1 168 ? 140.902 132.679 93.375  1.00 39.81  ? 115 PRO A CG  1 
ATOM   9046  C  CD  . PRO D 1 168 ? 140.700 134.154 93.562  1.00 42.88  ? 115 PRO A CD  1 
ATOM   9047  N  N   . ASN D 1 169 ? 144.257 133.452 96.623  1.00 35.76  ? 116 ASN A N   1 
ATOM   9048  C  CA  . ASN D 1 169 ? 145.622 133.812 96.973  1.00 30.91  ? 116 ASN A CA  1 
ATOM   9049  C  C   . ASN D 1 169 ? 146.597 132.812 96.371  1.00 34.91  ? 116 ASN A C   1 
ATOM   9050  O  O   . ASN D 1 169 ? 147.150 131.971 97.082  1.00 38.02  ? 116 ASN A O   1 
ATOM   9051  C  CB  . ASN D 1 169 ? 145.795 133.883 98.489  1.00 29.43  ? 116 ASN A CB  1 
ATOM   9052  C  CG  . ASN D 1 169 ? 144.963 134.971 99.123  1.00 32.56  ? 116 ASN A CG  1 
ATOM   9053  O  OD1 . ASN D 1 169 ? 144.894 135.079 100.340 1.00 32.52  ? 116 ASN A OD1 1 
ATOM   9054  N  ND2 . ASN D 1 169 ? 144.318 135.777 98.301  1.00 33.39  ? 116 ASN A ND2 1 
ATOM   9055  N  N   . LYS D 1 170 ? 146.800 132.889 95.060  1.00 34.60  ? 117 LYS A N   1 
ATOM   9056  C  CA  . LYS D 1 170 ? 147.724 132.019 94.352  1.00 32.18  ? 117 LYS A CA  1 
ATOM   9057  C  C   . LYS D 1 170 ? 148.492 132.837 93.329  1.00 34.08  ? 117 LYS A C   1 
ATOM   9058  O  O   . LYS D 1 170 ? 148.002 133.852 92.833  1.00 37.62  ? 117 LYS A O   1 
ATOM   9059  C  CB  . LYS D 1 170 ? 146.993 130.870 93.656  1.00 32.40  ? 117 LYS A CB  1 
ATOM   9060  C  CG  . LYS D 1 170 ? 146.295 129.933 94.602  1.00 35.71  ? 117 LYS A CG  1 
ATOM   9061  C  CD  . LYS D 1 170 ? 145.411 128.954 93.873  1.00 34.16  ? 117 LYS A CD  1 
ATOM   9062  C  CE  . LYS D 1 170 ? 144.740 128.011 94.849  1.00 41.08  ? 117 LYS A CE  1 
ATOM   9063  N  NZ  . LYS D 1 170 ? 143.688 127.197 94.194  1.00 49.23  ? 117 LYS A NZ  1 
ATOM   9064  N  N   . LEU D 1 171 ? 149.706 132.395 93.026  1.00 30.43  ? 118 LEU A N   1 
ATOM   9065  C  CA  . LEU D 1 171 ? 150.504 133.025 91.989  1.00 32.10  ? 118 LEU A CA  1 
ATOM   9066  C  C   . LEU D 1 171 ? 151.145 131.952 91.127  1.00 35.08  ? 118 LEU A C   1 
ATOM   9067  O  O   . LEU D 1 171 ? 151.563 130.907 91.630  1.00 39.25  ? 118 LEU A O   1 
ATOM   9068  C  CB  . LEU D 1 171 ? 151.574 133.965 92.574  1.00 35.03  ? 118 LEU A CB  1 
ATOM   9069  C  CG  . LEU D 1 171 ? 152.909 133.499 93.157  1.00 32.63  ? 118 LEU A CG  1 
ATOM   9070  C  CD1 . LEU D 1 171 ? 153.955 133.288 92.090  1.00 30.89  ? 118 LEU A CD1 1 
ATOM   9071  C  CD2 . LEU D 1 171 ? 153.407 134.508 94.165  1.00 32.11  ? 118 LEU A CD2 1 
ATOM   9072  N  N   . LEU D 1 172 ? 151.212 132.227 89.826  1.00 36.39  ? 119 LEU A N   1 
ATOM   9073  C  CA  . LEU D 1 172 ? 151.810 131.335 88.846  1.00 37.85  ? 119 LEU A CA  1 
ATOM   9074  C  C   . LEU D 1 172 ? 152.776 132.125 87.979  1.00 42.85  ? 119 LEU A C   1 
ATOM   9075  O  O   . LEU D 1 172 ? 152.435 133.207 87.488  1.00 48.96  ? 119 LEU A O   1 
ATOM   9076  C  CB  . LEU D 1 172 ? 150.745 130.672 87.977  1.00 36.85  ? 119 LEU A CB  1 
ATOM   9077  C  CG  . LEU D 1 172 ? 151.271 129.654 86.968  1.00 40.68  ? 119 LEU A CG  1 
ATOM   9078  C  CD1 . LEU D 1 172 ? 151.635 128.359 87.658  1.00 42.92  ? 119 LEU A CD1 1 
ATOM   9079  C  CD2 . LEU D 1 172 ? 150.254 129.412 85.883  1.00 45.63  ? 119 LEU A CD2 1 
ATOM   9080  N  N   . ARG D 1 173 ? 153.979 131.590 87.801  1.00 39.76  ? 120 ARG A N   1 
ATOM   9081  C  CA  . ARG D 1 173 ? 154.986 132.233 86.970  1.00 37.47  ? 120 ARG A CA  1 
ATOM   9082  C  C   . ARG D 1 173 ? 155.638 131.194 86.076  1.00 45.03  ? 120 ARG A C   1 
ATOM   9083  O  O   . ARG D 1 173 ? 156.077 130.146 86.557  1.00 48.92  ? 120 ARG A O   1 
ATOM   9084  C  CB  . ARG D 1 173 ? 156.035 132.940 87.832  1.00 37.39  ? 120 ARG A CB  1 
ATOM   9085  C  CG  . ARG D 1 173 ? 155.494 134.179 88.503  1.00 43.64  ? 120 ARG A CG  1 
ATOM   9086  C  CD  . ARG D 1 173 ? 156.415 134.716 89.564  1.00 41.28  ? 120 ARG A CD  1 
ATOM   9087  N  NE  . ARG D 1 173 ? 155.792 135.822 90.278  1.00 41.32  ? 120 ARG A NE  1 
ATOM   9088  C  CZ  . ARG D 1 173 ? 156.340 136.458 91.301  1.00 39.76  ? 120 ARG A CZ  1 
ATOM   9089  N  NH1 . ARG D 1 173 ? 157.534 136.128 91.758  1.00 44.50  ? 120 ARG A NH1 1 
ATOM   9090  N  NH2 . ARG D 1 173 ? 155.675 137.453 91.877  1.00 35.79  ? 120 ARG A NH2 1 
ATOM   9091  N  N   . ILE D 1 174 ? 155.710 131.493 84.782  1.00 46.36  ? 121 ILE A N   1 
ATOM   9092  C  CA  . ILE D 1 174 ? 156.250 130.581 83.780  1.00 45.26  ? 121 ILE A CA  1 
ATOM   9093  C  C   . ILE D 1 174 ? 157.518 131.189 83.200  1.00 49.23  ? 121 ILE A C   1 
ATOM   9094  O  O   . ILE D 1 174 ? 157.512 132.340 82.752  1.00 52.80  ? 121 ILE A O   1 
ATOM   9095  C  CB  . ILE D 1 174 ? 155.231 130.298 82.664  1.00 43.91  ? 121 ILE A CB  1 
ATOM   9096  C  CG1 . ILE D 1 174 ? 153.845 130.041 83.248  1.00 40.73  ? 121 ILE A CG1 1 
ATOM   9097  C  CG2 . ILE D 1 174 ? 155.676 129.118 81.829  1.00 45.26  ? 121 ILE A CG2 1 
ATOM   9098  C  CD1 . ILE D 1 174 ? 152.784 129.814 82.198  1.00 38.73  ? 121 ILE A CD1 1 
ATOM   9099  N  N   . THR D 1 175 ? 158.598 130.419 83.208  1.00 49.46  ? 122 THR A N   1 
ATOM   9100  C  CA  . THR D 1 175 ? 159.859 130.809 82.601  1.00 50.27  ? 122 THR A CA  1 
ATOM   9101  C  C   . THR D 1 175 ? 159.938 130.249 81.186  1.00 55.83  ? 122 THR A C   1 
ATOM   9102  O  O   . THR D 1 175 ? 159.298 129.250 80.856  1.00 58.09  ? 122 THR A O   1 
ATOM   9103  C  CB  . THR D 1 175 ? 161.036 130.310 83.439  1.00 52.64  ? 122 THR A CB  1 
ATOM   9104  O  OG1 . THR D 1 175 ? 160.765 130.554 84.822  1.00 55.42  ? 122 THR A OG1 1 
ATOM   9105  C  CG2 . THR D 1 175 ? 162.306 131.040 83.067  1.00 59.44  ? 122 THR A CG2 1 
ATOM   9106  N  N   . GLU D 1 176 ? 160.733 130.913 80.346  1.00 59.93  ? 123 GLU A N   1 
ATOM   9107  C  CA  . GLU D 1 176 ? 160.800 130.542 78.938  1.00 60.86  ? 123 GLU A CA  1 
ATOM   9108  C  C   . GLU D 1 176 ? 161.277 129.113 78.729  1.00 62.86  ? 123 GLU A C   1 
ATOM   9109  O  O   . GLU D 1 176 ? 160.984 128.524 77.686  1.00 62.69  ? 123 GLU A O   1 
ATOM   9110  C  CB  . GLU D 1 176 ? 161.715 131.501 78.184  1.00 66.25  ? 123 GLU A CB  1 
ATOM   9111  C  CG  . GLU D 1 176 ? 163.166 131.432 78.614  1.00 71.53  ? 123 GLU A CG  1 
ATOM   9112  C  CD  . GLU D 1 176 ? 164.059 132.307 77.766  1.00 80.86  ? 123 GLU A CD  1 
ATOM   9113  O  OE1 . GLU D 1 176 ? 163.528 133.030 76.898  1.00 84.57  ? 123 GLU A OE1 1 
ATOM   9114  O  OE2 . GLU D 1 176 ? 165.291 132.269 77.964  1.00 84.90  ? 123 GLU A OE2 1 
ATOM   9115  N  N   . ASP D 1 177 ? 162.002 128.540 79.686  1.00 64.55  ? 124 ASP A N   1 
ATOM   9116  C  CA  . ASP D 1 177 ? 162.468 127.168 79.555  1.00 62.18  ? 124 ASP A CA  1 
ATOM   9117  C  C   . ASP D 1 177 ? 161.414 126.146 79.947  1.00 60.91  ? 124 ASP A C   1 
ATOM   9118  O  O   . ASP D 1 177 ? 161.654 124.946 79.790  1.00 65.35  ? 124 ASP A O   1 
ATOM   9119  C  CB  . ASP D 1 177 ? 163.724 126.949 80.401  1.00 63.65  ? 124 ASP A CB  1 
ATOM   9120  C  CG  . ASP D 1 177 ? 163.453 127.052 81.887  1.00 64.57  ? 124 ASP A CG  1 
ATOM   9121  O  OD1 . ASP D 1 177 ? 162.471 127.715 82.272  1.00 58.42  ? 124 ASP A OD1 1 
ATOM   9122  O  OD2 . ASP D 1 177 ? 164.226 126.472 82.675  1.00 69.06  ? 124 ASP A OD2 1 
ATOM   9123  N  N   . GLY D 1 178 ? 160.264 126.585 80.444  1.00 57.74  ? 125 GLY A N   1 
ATOM   9124  C  CA  . GLY D 1 178 ? 159.217 125.684 80.865  1.00 52.67  ? 125 GLY A CA  1 
ATOM   9125  C  C   . GLY D 1 178 ? 159.120 125.452 82.353  1.00 49.21  ? 125 GLY A C   1 
ATOM   9126  O  O   . GLY D 1 178 ? 158.351 124.585 82.772  1.00 53.08  ? 125 GLY A O   1 
ATOM   9127  N  N   . THR D 1 179 ? 159.877 126.186 83.161  1.00 48.44  ? 126 THR A N   1 
ATOM   9128  C  CA  . THR D 1 179 ? 159.812 126.034 84.607  1.00 45.21  ? 126 THR A CA  1 
ATOM   9129  C  C   . THR D 1 179 ? 158.653 126.847 85.168  1.00 43.83  ? 126 THR A C   1 
ATOM   9130  O  O   . THR D 1 179 ? 158.491 128.024 84.839  1.00 48.62  ? 126 THR A O   1 
ATOM   9131  C  CB  . THR D 1 179 ? 161.125 126.472 85.247  1.00 48.83  ? 126 THR A CB  1 
ATOM   9132  O  OG1 . THR D 1 179 ? 162.200 125.701 84.703  1.00 55.99  ? 126 THR A OG1 1 
ATOM   9133  C  CG2 . THR D 1 179 ? 161.080 126.266 86.743  1.00 41.68  ? 126 THR A CG2 1 
ATOM   9134  N  N   . LEU D 1 180 ? 157.850 126.217 86.016  1.00 40.37  ? 127 LEU A N   1 
ATOM   9135  C  CA  . LEU D 1 180 ? 156.696 126.846 86.636  1.00 39.45  ? 127 LEU A CA  1 
ATOM   9136  C  C   . LEU D 1 180 ? 156.926 126.985 88.130  1.00 37.96  ? 127 LEU A C   1 
ATOM   9137  O  O   . LEU D 1 180 ? 157.365 126.032 88.787  1.00 40.68  ? 127 LEU A O   1 
ATOM   9138  C  CB  . LEU D 1 180 ? 155.427 126.036 86.386  1.00 35.07  ? 127 LEU A CB  1 
ATOM   9139  C  CG  . LEU D 1 180 ? 154.976 125.965 84.938  1.00 41.06  ? 127 LEU A CG  1 
ATOM   9140  C  CD1 . LEU D 1 180 ? 155.018 124.544 84.455  1.00 42.56  ? 127 LEU A CD1 1 
ATOM   9141  C  CD2 . LEU D 1 180 ? 153.588 126.520 84.826  1.00 42.89  ? 127 LEU A CD2 1 
ATOM   9142  N  N   . LEU D 1 181 ? 156.636 128.175 88.650  1.00 34.35  ? 128 LEU A N   1 
ATOM   9143  C  CA  . LEU D 1 181 ? 156.586 128.438 90.082  1.00 33.30  ? 128 LEU A CA  1 
ATOM   9144  C  C   . LEU D 1 181 ? 155.136 128.695 90.462  1.00 35.17  ? 128 LEU A C   1 
ATOM   9145  O  O   . LEU D 1 181 ? 154.489 129.576 89.888  1.00 38.99  ? 128 LEU A O   1 
ATOM   9146  C  CB  . LEU D 1 181 ? 157.465 129.626 90.462  1.00 34.49  ? 128 LEU A CB  1 
ATOM   9147  C  CG  . LEU D 1 181 ? 157.404 130.061 91.927  1.00 33.66  ? 128 LEU A CG  1 
ATOM   9148  C  CD1 . LEU D 1 181 ? 158.003 129.010 92.834  1.00 31.58  ? 128 LEU A CD1 1 
ATOM   9149  C  CD2 . LEU D 1 181 ? 158.093 131.388 92.122  1.00 34.28  ? 128 LEU A CD2 1 
ATOM   9150  N  N   . TYR D 1 182 ? 154.634 127.921 91.421  1.00 29.91  ? 129 TYR A N   1 
ATOM   9151  C  CA  . TYR D 1 182 ? 153.242 127.951 91.842  1.00 27.23  ? 129 TYR A CA  1 
ATOM   9152  C  C   . TYR D 1 182 ? 153.225 128.130 93.349  1.00 29.50  ? 129 TYR A C   1 
ATOM   9153  O  O   . TYR D 1 182 ? 153.752 127.288 94.081  1.00 36.68  ? 129 TYR A O   1 
ATOM   9154  C  CB  . TYR D 1 182 ? 152.535 126.660 91.424  1.00 32.90  ? 129 TYR A CB  1 
ATOM   9155  C  CG  . TYR D 1 182 ? 151.067 126.560 91.749  1.00 38.43  ? 129 TYR A CG  1 
ATOM   9156  C  CD1 . TYR D 1 182 ? 150.199 127.600 91.473  1.00 37.96  ? 129 TYR A CD1 1 
ATOM   9157  C  CD2 . TYR D 1 182 ? 150.545 125.401 92.291  1.00 39.98  ? 129 TYR A CD2 1 
ATOM   9158  C  CE1 . TYR D 1 182 ? 148.861 127.496 91.755  1.00 40.30  ? 129 TYR A CE1 1 
ATOM   9159  C  CE2 . TYR D 1 182 ? 149.214 125.290 92.576  1.00 41.75  ? 129 TYR A CE2 1 
ATOM   9160  C  CZ  . TYR D 1 182 ? 148.374 126.338 92.307  1.00 45.25  ? 129 TYR A CZ  1 
ATOM   9161  O  OH  . TYR D 1 182 ? 147.040 126.219 92.593  1.00 45.93  ? 129 TYR A OH  1 
ATOM   9162  N  N   . THR D 1 183 ? 152.634 129.220 93.813  1.00 29.90  ? 130 THR A N   1 
ATOM   9163  C  CA  . THR D 1 183 ? 152.653 129.560 95.228  1.00 29.93  ? 130 THR A CA  1 
ATOM   9164  C  C   . THR D 1 183 ? 151.232 129.802 95.700  1.00 31.91  ? 130 THR A C   1 
ATOM   9165  O  O   . THR D 1 183 ? 150.422 130.365 94.964  1.00 38.26  ? 130 THR A O   1 
ATOM   9166  C  CB  . THR D 1 183 ? 153.515 130.802 95.484  1.00 36.02  ? 130 THR A CB  1 
ATOM   9167  O  OG1 . THR D 1 183 ? 154.865 130.544 95.083  1.00 35.20  ? 130 THR A OG1 1 
ATOM   9168  C  CG2 . THR D 1 183 ? 153.503 131.180 96.947  1.00 32.59  ? 130 THR A CG2 1 
ATOM   9169  N  N   . MET D 1 184 ? 150.921 129.358 96.915  1.00 29.90  ? 131 MET A N   1 
ATOM   9170  C  CA  . MET D 1 184 ? 149.613 129.628 97.496  1.00 26.73  ? 131 MET A CA  1 
ATOM   9171  C  C   . MET D 1 184 ? 149.766 129.962 98.972  1.00 27.66  ? 131 MET A C   1 
ATOM   9172  O  O   . MET D 1 184 ? 150.805 129.713 99.578  1.00 33.84  ? 131 MET A O   1 
ATOM   9173  C  CB  . MET D 1 184 ? 148.651 128.452 97.305  1.00 27.94  ? 131 MET A CB  1 
ATOM   9174  C  CG  . MET D 1 184 ? 149.111 127.144 97.899  1.00 37.04  ? 131 MET A CG  1 
ATOM   9175  S  SD  . MET D 1 184 ? 147.922 125.836 97.604  1.00 47.78  ? 131 MET A SD  1 
ATOM   9176  C  CE  . MET D 1 184 ? 147.802 125.910 95.828  1.00 32.67  ? 131 MET A CE  1 
ATOM   9177  N  N   . ARG D 1 185 ? 148.726 130.557 99.541  1.00 26.87  ? 132 ARG A N   1 
ATOM   9178  C  CA  . ARG D 1 185 ? 148.710 130.936 100.948 1.00 26.29  ? 132 ARG A CA  1 
ATOM   9179  C  C   . ARG D 1 185 ? 147.666 130.101 101.670 1.00 25.77  ? 132 ARG A C   1 
ATOM   9180  O  O   . ARG D 1 185 ? 146.485 130.140 101.316 1.00 28.09  ? 132 ARG A O   1 
ATOM   9181  C  CB  . ARG D 1 185 ? 148.417 132.424 101.117 1.00 25.25  ? 132 ARG A CB  1 
ATOM   9182  C  CG  . ARG D 1 185 ? 148.140 132.830 102.544 1.00 23.86  ? 132 ARG A CG  1 
ATOM   9183  C  CD  . ARG D 1 185 ? 147.986 134.328 102.685 1.00 28.04  ? 132 ARG A CD  1 
ATOM   9184  N  NE  . ARG D 1 185 ? 147.409 134.677 103.974 1.00 36.18  ? 132 ARG A NE  1 
ATOM   9185  C  CZ  . ARG D 1 185 ? 146.145 135.026 104.157 1.00 40.57  ? 132 ARG A CZ  1 
ATOM   9186  N  NH1 . ARG D 1 185 ? 145.309 135.151 103.141 1.00 31.85  ? 132 ARG A NH1 1 
ATOM   9187  N  NH2 . ARG D 1 185 ? 145.705 135.239 105.391 1.00 45.33  ? 132 ARG A NH2 1 
ATOM   9188  N  N   . LEU D 1 186 ? 148.098 129.363 102.688 1.00 27.68  ? 133 LEU A N   1 
ATOM   9189  C  CA  . LEU D 1 186 ? 147.251 128.386 103.348 1.00 23.08  ? 133 LEU A CA  1 
ATOM   9190  C  C   . LEU D 1 186 ? 147.246 128.602 104.849 1.00 24.89  ? 133 LEU A C   1 
ATOM   9191  O  O   . LEU D 1 186 ? 148.190 129.150 105.419 1.00 32.98  ? 133 LEU A O   1 
ATOM   9192  C  CB  . LEU D 1 186 ? 147.708 126.956 103.074 1.00 25.35  ? 133 LEU A CB  1 
ATOM   9193  C  CG  . LEU D 1 186 ? 147.898 126.491 101.639 1.00 26.20  ? 133 LEU A CG  1 
ATOM   9194  C  CD1 . LEU D 1 186 ? 148.561 125.145 101.643 1.00 28.19  ? 133 LEU A CD1 1 
ATOM   9195  C  CD2 . LEU D 1 186 ? 146.574 126.430 100.928 1.00 26.99  ? 133 LEU A CD2 1 
ATOM   9196  N  N   . THR D 1 187 ? 146.158 128.169 105.476 1.00 25.19  ? 134 THR A N   1 
ATOM   9197  C  CA  . THR D 1 187 ? 146.075 127.982 106.917 1.00 29.52  ? 134 THR A CA  1 
ATOM   9198  C  C   . THR D 1 187 ? 145.743 126.521 107.165 1.00 30.41  ? 134 THR A C   1 
ATOM   9199  O  O   . THR D 1 187 ? 144.752 126.016 106.635 1.00 36.32  ? 134 THR A O   1 
ATOM   9200  C  CB  . THR D 1 187 ? 145.012 128.881 107.543 1.00 32.50  ? 134 THR A CB  1 
ATOM   9201  O  OG1 . THR D 1 187 ? 145.349 130.253 107.319 1.00 42.09  ? 134 THR A OG1 1 
ATOM   9202  C  CG2 . THR D 1 187 ? 144.932 128.631 109.026 1.00 29.20  ? 134 THR A CG2 1 
ATOM   9203  N  N   . VAL D 1 188 ? 146.567 125.848 107.958 1.00 29.52  ? 135 VAL A N   1 
ATOM   9204  C  CA  . VAL D 1 188 ? 146.492 124.404 108.137 1.00 30.81  ? 135 VAL A CA  1 
ATOM   9205  C  C   . VAL D 1 188 ? 146.373 124.090 109.620 1.00 33.19  ? 135 VAL A C   1 
ATOM   9206  O  O   . VAL D 1 188 ? 147.172 124.580 110.424 1.00 35.46  ? 135 VAL A O   1 
ATOM   9207  C  CB  . VAL D 1 188 ? 147.725 123.704 107.542 1.00 30.27  ? 135 VAL A CB  1 
ATOM   9208  C  CG1 . VAL D 1 188 ? 147.658 122.221 107.787 1.00 32.05  ? 135 VAL A CG1 1 
ATOM   9209  C  CG2 . VAL D 1 188 ? 147.833 123.993 106.067 1.00 29.21  ? 135 VAL A CG2 1 
ATOM   9210  N  N   . ARG D 1 189 ? 145.387 123.273 109.978 1.00 33.38  ? 136 ARG A N   1 
ATOM   9211  C  CA  . ARG D 1 189 ? 145.275 122.706 111.316 1.00 33.88  ? 136 ARG A CA  1 
ATOM   9212  C  C   . ARG D 1 189 ? 145.767 121.268 111.268 1.00 35.65  ? 136 ARG A C   1 
ATOM   9213  O  O   . ARG D 1 189 ? 145.226 120.453 110.518 1.00 42.83  ? 136 ARG A O   1 
ATOM   9214  C  CB  . ARG D 1 189 ? 143.837 122.753 111.814 1.00 37.47  ? 136 ARG A CB  1 
ATOM   9215  C  CG  . ARG D 1 189 ? 143.222 124.123 111.818 1.00 44.38  ? 136 ARG A CG  1 
ATOM   9216  C  CD  . ARG D 1 189 ? 141.762 124.021 112.173 1.00 51.98  ? 136 ARG A CD  1 
ATOM   9217  N  NE  . ARG D 1 189 ? 141.495 122.825 112.960 1.00 60.09  ? 136 ARG A NE  1 
ATOM   9218  C  CZ  . ARG D 1 189 ? 140.282 122.384 113.261 1.00 67.77  ? 136 ARG A CZ  1 
ATOM   9219  N  NH1 . ARG D 1 189 ? 139.196 123.027 112.865 1.00 70.06  ? 136 ARG A NH1 1 
ATOM   9220  N  NH2 . ARG D 1 189 ? 140.154 121.269 113.974 1.00 65.03  ? 136 ARG A NH2 1 
ATOM   9221  N  N   . ALA D 1 190 ? 146.773 120.952 112.074 1.00 33.40  ? 137 ALA A N   1 
ATOM   9222  C  CA  . ALA D 1 190 ? 147.463 119.677 111.979 1.00 33.92  ? 137 ALA A CA  1 
ATOM   9223  C  C   . ALA D 1 190 ? 147.506 118.992 113.335 1.00 39.33  ? 137 ALA A C   1 
ATOM   9224  O  O   . ALA D 1 190 ? 147.524 119.645 114.380 1.00 42.71  ? 137 ALA A O   1 
ATOM   9225  C  CB  . ALA D 1 190 ? 148.878 119.858 111.444 1.00 32.86  ? 137 ALA A CB  1 
ATOM   9226  N  N   . GLU D 1 191 ? 147.528 117.663 113.302 1.00 39.10  ? 138 GLU A N   1 
ATOM   9227  C  CA  . GLU D 1 191 ? 147.518 116.858 114.515 1.00 42.69  ? 138 GLU A CA  1 
ATOM   9228  C  C   . GLU D 1 191 ? 148.906 116.797 115.130 1.00 48.69  ? 138 GLU A C   1 
ATOM   9229  O  O   . GLU D 1 191 ? 149.890 116.551 114.431 1.00 55.89  ? 138 GLU A O   1 
ATOM   9230  C  CB  . GLU D 1 191 ? 147.031 115.447 114.207 1.00 44.49  ? 138 GLU A CB  1 
ATOM   9231  C  CG  . GLU D 1 191 ? 145.608 115.386 113.731 1.00 55.56  ? 138 GLU A CG  1 
ATOM   9232  C  CD  . GLU D 1 191 ? 145.225 114.011 113.242 1.00 76.03  ? 138 GLU A CD  1 
ATOM   9233  O  OE1 . GLU D 1 191 ? 145.966 113.050 113.538 1.00 86.31  ? 138 GLU A OE1 1 
ATOM   9234  O  OE2 . GLU D 1 191 ? 144.189 113.892 112.556 1.00 79.92  ? 138 GLU A OE2 1 
ATOM   9235  N  N   . CYS D 1 192 ? 148.982 117.015 116.440 1.00 45.02  ? 139 CYS A N   1 
ATOM   9236  C  CA  . CYS D 1 192 ? 150.237 116.944 117.185 1.00 49.51  ? 139 CYS A CA  1 
ATOM   9237  C  C   . CYS D 1 192 ? 150.004 116.075 118.411 1.00 58.28  ? 139 CYS A C   1 
ATOM   9238  O  O   . CYS D 1 192 ? 149.657 116.582 119.483 1.00 68.04  ? 139 CYS A O   1 
ATOM   9239  C  CB  . CYS D 1 192 ? 150.732 118.339 117.569 1.00 46.80  ? 139 CYS A CB  1 
ATOM   9240  S  SG  . CYS D 1 192 ? 152.357 118.383 118.359 1.00 77.96  ? 139 CYS A SG  1 
ATOM   9241  N  N   . PRO D 1 193 ? 150.158 114.758 118.288 1.00 56.49  ? 140 PRO A N   1 
ATOM   9242  C  CA  . PRO D 1 193 ? 149.942 113.878 119.448 1.00 56.16  ? 140 PRO A CA  1 
ATOM   9243  C  C   . PRO D 1 193 ? 150.955 114.170 120.542 1.00 63.30  ? 140 PRO A C   1 
ATOM   9244  O  O   . PRO D 1 193 ? 152.164 114.053 120.341 1.00 68.80  ? 140 PRO A O   1 
ATOM   9245  C  CB  . PRO D 1 193 ? 150.127 112.472 118.867 1.00 55.63  ? 140 PRO A CB  1 
ATOM   9246  C  CG  . PRO D 1 193 ? 150.083 112.641 117.386 1.00 62.14  ? 140 PRO A CG  1 
ATOM   9247  C  CD  . PRO D 1 193 ? 150.596 114.007 117.105 1.00 56.93  ? 140 PRO A CD  1 
ATOM   9248  N  N   . MET D 1 194 ? 150.450 114.539 121.713 1.00 61.40  ? 141 MET A N   1 
ATOM   9249  C  CA  . MET D 1 194 ? 151.275 115.043 122.799 1.00 59.15  ? 141 MET A CA  1 
ATOM   9250  C  C   . MET D 1 194 ? 151.292 114.066 123.961 1.00 62.67  ? 141 MET A C   1 
ATOM   9251  O  O   . MET D 1 194 ? 150.256 113.509 124.332 1.00 67.56  ? 141 MET A O   1 
ATOM   9252  C  CB  . MET D 1 194 ? 150.765 116.394 123.286 1.00 57.44  ? 141 MET A CB  1 
ATOM   9253  C  CG  . MET D 1 194 ? 150.794 117.463 122.233 1.00 60.66  ? 141 MET A CG  1 
ATOM   9254  S  SD  . MET D 1 194 ? 150.031 118.999 122.755 1.00 68.40  ? 141 MET A SD  1 
ATOM   9255  C  CE  . MET D 1 194 ? 150.060 119.875 121.205 1.00 51.30  ? 141 MET A CE  1 
ATOM   9256  N  N   . HIS D 1 195 ? 152.475 113.861 124.528 1.00 61.85  ? 142 HIS A N   1 
ATOM   9257  C  CA  . HIS D 1 195 ? 152.639 113.108 125.763 1.00 60.61  ? 142 HIS A CA  1 
ATOM   9258  C  C   . HIS D 1 195 ? 152.859 114.101 126.895 1.00 59.77  ? 142 HIS A C   1 
ATOM   9259  O  O   . HIS D 1 195 ? 153.837 114.855 126.881 1.00 63.56  ? 142 HIS A O   1 
ATOM   9260  C  CB  . HIS D 1 195 ? 153.812 112.136 125.665 1.00 65.97  ? 142 HIS A CB  1 
ATOM   9261  C  CG  . HIS D 1 195 ? 153.723 111.197 124.506 1.00 79.58  ? 142 HIS A CG  1 
ATOM   9262  N  ND1 . HIS D 1 195 ? 152.987 110.034 124.545 1.00 83.44  ? 142 HIS A ND1 1 
ATOM   9263  C  CD2 . HIS D 1 195 ? 154.275 111.251 123.272 1.00 85.36  ? 142 HIS A CD2 1 
ATOM   9264  C  CE1 . HIS D 1 195 ? 153.089 109.412 123.385 1.00 87.13  ? 142 HIS A CE1 1 
ATOM   9265  N  NE2 . HIS D 1 195 ? 153.866 110.130 122.595 1.00 85.54  ? 142 HIS A NE2 1 
ATOM   9266  N  N   . LEU D 1 196 ? 151.960 114.098 127.869 1.00 53.16  ? 143 LEU A N   1 
ATOM   9267  C  CA  . LEU D 1 196 ? 151.945 115.102 128.925 1.00 48.32  ? 143 LEU A CA  1 
ATOM   9268  C  C   . LEU D 1 196 ? 152.329 114.511 130.278 1.00 53.03  ? 143 LEU A C   1 
ATOM   9269  O  O   . LEU D 1 196 ? 151.758 114.866 131.307 1.00 54.35  ? 143 LEU A O   1 
ATOM   9270  C  CB  . LEU D 1 196 ? 150.576 115.770 129.003 1.00 47.64  ? 143 LEU A CB  1 
ATOM   9271  C  CG  . LEU D 1 196 ? 150.057 116.405 127.712 1.00 43.01  ? 143 LEU A CG  1 
ATOM   9272  C  CD1 . LEU D 1 196 ? 148.613 116.793 127.857 1.00 44.68  ? 143 LEU A CD1 1 
ATOM   9273  C  CD2 . LEU D 1 196 ? 150.877 117.614 127.337 1.00 44.09  ? 143 LEU A CD2 1 
ATOM   9274  N  N   . GLU D 1 197 ? 153.299 113.597 130.297 1.00 57.30  ? 144 GLU A N   1 
ATOM   9275  C  CA  . GLU D 1 197 ? 153.776 113.066 131.567 1.00 56.06  ? 144 GLU A CA  1 
ATOM   9276  C  C   . GLU D 1 197 ? 154.616 114.076 132.336 1.00 57.28  ? 144 GLU A C   1 
ATOM   9277  O  O   . GLU D 1 197 ? 154.710 113.976 133.561 1.00 59.41  ? 144 GLU A O   1 
ATOM   9278  C  CB  . GLU D 1 197 ? 154.591 111.789 131.350 1.00 53.36  ? 144 GLU A CB  1 
ATOM   9279  C  CG  . GLU D 1 197 ? 153.771 110.589 130.915 1.00 60.80  ? 144 GLU A CG  1 
ATOM   9280  C  CD  . GLU D 1 197 ? 153.510 110.574 129.426 1.00 72.96  ? 144 GLU A CD  1 
ATOM   9281  O  OE1 . GLU D 1 197 ? 154.306 111.184 128.685 1.00 75.09  ? 144 GLU A OE1 1 
ATOM   9282  O  OE2 . GLU D 1 197 ? 152.513 109.957 128.995 1.00 72.76  ? 144 GLU A OE2 1 
ATOM   9283  N  N   . ASP D 1 198 ? 155.217 115.046 131.650 1.00 56.56  ? 145 ASP A N   1 
ATOM   9284  C  CA  . ASP D 1 198 ? 156.099 116.021 132.272 1.00 51.87  ? 145 ASP A CA  1 
ATOM   9285  C  C   . ASP D 1 198 ? 155.428 117.369 132.478 1.00 52.42  ? 145 ASP A C   1 
ATOM   9286  O  O   . ASP D 1 198 ? 156.120 118.365 132.696 1.00 57.23  ? 145 ASP A O   1 
ATOM   9287  C  CB  . ASP D 1 198 ? 157.365 116.201 131.436 1.00 52.35  ? 145 ASP A CB  1 
ATOM   9288  C  CG  . ASP D 1 198 ? 158.173 114.936 131.323 1.00 63.80  ? 145 ASP A CG  1 
ATOM   9289  O  OD1 . ASP D 1 198 ? 157.730 113.900 131.851 1.00 69.07  ? 145 ASP A OD1 1 
ATOM   9290  O  OD2 . ASP D 1 198 ? 159.254 114.974 130.703 1.00 68.56  ? 145 ASP A OD2 1 
ATOM   9291  N  N   . PHE D 1 199 ? 154.109 117.424 132.402 1.00 46.12  ? 146 PHE A N   1 
ATOM   9292  C  CA  . PHE D 1 199 ? 153.413 118.692 132.531 1.00 43.20  ? 146 PHE A CA  1 
ATOM   9293  C  C   . PHE D 1 199 ? 153.704 119.313 133.895 1.00 48.87  ? 146 PHE A C   1 
ATOM   9294  O  O   . PHE D 1 199 ? 153.684 118.613 134.911 1.00 53.73  ? 146 PHE A O   1 
ATOM   9295  C  CB  . PHE D 1 199 ? 151.913 118.478 132.355 1.00 41.79  ? 146 PHE A CB  1 
ATOM   9296  C  CG  . PHE D 1 199 ? 151.113 119.739 132.366 1.00 43.01  ? 146 PHE A CG  1 
ATOM   9297  C  CD1 . PHE D 1 199 ? 150.675 120.288 133.551 1.00 46.71  ? 146 PHE A CD1 1 
ATOM   9298  C  CD2 . PHE D 1 199 ? 150.779 120.365 131.190 1.00 43.30  ? 146 PHE A CD2 1 
ATOM   9299  C  CE1 . PHE D 1 199 ? 149.941 121.443 133.559 1.00 49.38  ? 146 PHE A CE1 1 
ATOM   9300  C  CE2 . PHE D 1 199 ? 150.035 121.518 131.198 1.00 44.85  ? 146 PHE A CE2 1 
ATOM   9301  C  CZ  . PHE D 1 199 ? 149.620 122.057 132.382 1.00 47.95  ? 146 PHE A CZ  1 
ATOM   9302  N  N   . PRO D 1 200 ? 153.970 120.618 133.963 1.00 47.33  ? 147 PRO A N   1 
ATOM   9303  C  CA  . PRO D 1 200 ? 154.056 121.592 132.877 1.00 46.06  ? 147 PRO A CA  1 
ATOM   9304  C  C   . PRO D 1 200 ? 155.471 121.849 132.394 1.00 46.04  ? 147 PRO A C   1 
ATOM   9305  O  O   . PRO D 1 200 ? 155.761 122.933 131.913 1.00 47.55  ? 147 PRO A O   1 
ATOM   9306  C  CB  . PRO D 1 200 ? 153.472 122.843 133.522 1.00 42.80  ? 147 PRO A CB  1 
ATOM   9307  C  CG  . PRO D 1 200 ? 153.962 122.755 134.926 1.00 43.27  ? 147 PRO A CG  1 
ATOM   9308  C  CD  . PRO D 1 200 ? 153.963 121.288 135.272 1.00 44.57  ? 147 PRO A CD  1 
ATOM   9309  N  N   . MET D 1 201 ? 156.376 120.886 132.499 1.00 45.37  ? 148 MET A N   1 
ATOM   9310  C  CA  . MET D 1 201 ? 157.761 121.048 132.075 1.00 45.21  ? 148 MET A CA  1 
ATOM   9311  C  C   . MET D 1 201 ? 158.081 120.147 130.889 1.00 46.68  ? 148 MET A C   1 
ATOM   9312  O  O   . MET D 1 201 ? 159.114 119.481 130.856 1.00 51.69  ? 148 MET A O   1 
ATOM   9313  C  CB  . MET D 1 201 ? 158.710 120.767 133.233 1.00 47.91  ? 148 MET A CB  1 
ATOM   9314  C  CG  . MET D 1 201 ? 158.727 121.860 134.276 1.00 56.15  ? 148 MET A CG  1 
ATOM   9315  S  SD  . MET D 1 201 ? 159.360 121.343 135.874 1.00 69.76  ? 148 MET A SD  1 
ATOM   9316  C  CE  . MET D 1 201 ? 158.041 120.260 136.392 1.00 58.71  ? 148 MET A CE  1 
ATOM   9317  N  N   . ASP D 1 202 ? 157.192 120.116 129.906 1.00 46.81  ? 149 ASP A N   1 
ATOM   9318  C  CA  . ASP D 1 202 ? 157.262 119.166 128.809 1.00 48.48  ? 149 ASP A CA  1 
ATOM   9319  C  C   . ASP D 1 202 ? 157.633 119.859 127.504 1.00 51.66  ? 149 ASP A C   1 
ATOM   9320  O  O   . ASP D 1 202 ? 157.470 121.069 127.344 1.00 53.34  ? 149 ASP A O   1 
ATOM   9321  C  CB  . ASP D 1 202 ? 155.928 118.440 128.652 1.00 47.96  ? 149 ASP A CB  1 
ATOM   9322  C  CG  . ASP D 1 202 ? 154.768 119.390 128.585 1.00 46.82  ? 149 ASP A CG  1 
ATOM   9323  O  OD1 . ASP D 1 202 ? 154.953 120.559 128.958 1.00 45.19  ? 149 ASP A OD1 1 
ATOM   9324  O  OD2 . ASP D 1 202 ? 153.676 118.982 128.158 1.00 49.01  ? 149 ASP A OD2 1 
ATOM   9325  N  N   . ALA D 1 203 ? 158.142 119.063 126.567 1.00 54.72  ? 150 ALA A N   1 
ATOM   9326  C  CA  . ALA D 1 203 ? 158.521 119.534 125.246 1.00 48.52  ? 150 ALA A CA  1 
ATOM   9327  C  C   . ALA D 1 203 ? 157.888 118.636 124.195 1.00 50.81  ? 150 ALA A C   1 
ATOM   9328  O  O   . ALA D 1 203 ? 157.711 117.436 124.410 1.00 56.25  ? 150 ALA A O   1 
ATOM   9329  C  CB  . ALA D 1 203 ? 160.039 119.557 125.072 1.00 43.21  ? 150 ALA A CB  1 
ATOM   9330  N  N   . HIS D 1 204 ? 157.544 119.227 123.058 1.00 47.90  ? 151 HIS A N   1 
ATOM   9331  C  CA  . HIS D 1 204 ? 156.831 118.517 122.009 1.00 45.15  ? 151 HIS A CA  1 
ATOM   9332  C  C   . HIS D 1 204 ? 157.471 118.776 120.658 1.00 49.04  ? 151 HIS A C   1 
ATOM   9333  O  O   . HIS D 1 204 ? 158.064 119.827 120.425 1.00 53.52  ? 151 HIS A O   1 
ATOM   9334  C  CB  . HIS D 1 204 ? 155.365 118.931 121.959 1.00 46.21  ? 151 HIS A CB  1 
ATOM   9335  C  CG  . HIS D 1 204 ? 154.674 118.841 123.278 1.00 52.24  ? 151 HIS A CG  1 
ATOM   9336  N  ND1 . HIS D 1 204 ? 154.337 119.953 124.017 1.00 54.48  ? 151 HIS A ND1 1 
ATOM   9337  C  CD2 . HIS D 1 204 ? 154.270 117.772 124.001 1.00 53.56  ? 151 HIS A CD2 1 
ATOM   9338  C  CE1 . HIS D 1 204 ? 153.748 119.573 125.135 1.00 55.08  ? 151 HIS A CE1 1 
ATOM   9339  N  NE2 . HIS D 1 204 ? 153.696 118.254 125.150 1.00 57.94  ? 151 HIS A NE2 1 
ATOM   9340  N  N   . ALA D 1 205 ? 157.337 117.803 119.766 1.00 48.92  ? 152 ALA A N   1 
ATOM   9341  C  CA  . ALA D 1 205 ? 157.742 117.942 118.371 1.00 43.02  ? 152 ALA A CA  1 
ATOM   9342  C  C   . ALA D 1 205 ? 156.483 117.798 117.528 1.00 46.07  ? 152 ALA A C   1 
ATOM   9343  O  O   . ALA D 1 205 ? 156.027 116.682 117.271 1.00 53.86  ? 152 ALA A O   1 
ATOM   9344  C  CB  . ALA D 1 205 ? 158.793 116.910 117.987 1.00 40.51  ? 152 ALA A CB  1 
ATOM   9345  N  N   . CYS D 1 206 ? 155.912 118.922 117.119 1.00 43.53  ? 153 CYS A N   1 
ATOM   9346  C  CA  . CYS D 1 206 ? 154.707 118.896 116.306 1.00 43.38  ? 153 CYS A CA  1 
ATOM   9347  C  C   . CYS D 1 206 ? 155.070 118.678 114.844 1.00 42.03  ? 153 CYS A C   1 
ATOM   9348  O  O   . CYS D 1 206 ? 155.832 119.471 114.281 1.00 43.44  ? 153 CYS A O   1 
ATOM   9349  C  CB  . CYS D 1 206 ? 153.919 120.183 116.479 1.00 40.18  ? 153 CYS A CB  1 
ATOM   9350  S  SG  . CYS D 1 206 ? 153.065 120.270 118.062 1.00 80.00  ? 153 CYS A SG  1 
ATOM   9351  N  N   . PRO D 1 207 ? 154.579 117.621 114.208 1.00 38.68  ? 154 PRO A N   1 
ATOM   9352  C  CA  . PRO D 1 207 ? 154.971 117.321 112.834 1.00 37.96  ? 154 PRO A CA  1 
ATOM   9353  C  C   . PRO D 1 207 ? 153.990 117.857 111.806 1.00 37.95  ? 154 PRO A C   1 
ATOM   9354  O  O   . PRO D 1 207 ? 152.796 118.021 112.057 1.00 40.68  ? 154 PRO A O   1 
ATOM   9355  C  CB  . PRO D 1 207 ? 154.974 115.790 112.826 1.00 38.45  ? 154 PRO A CB  1 
ATOM   9356  C  CG  . PRO D 1 207 ? 153.855 115.448 113.741 1.00 41.06  ? 154 PRO A CG  1 
ATOM   9357  C  CD  . PRO D 1 207 ? 153.775 116.535 114.787 1.00 40.55  ? 154 PRO A CD  1 
ATOM   9358  N  N   . LEU D 1 208 ? 154.529 118.131 110.625 1.00 34.65  ? 155 LEU A N   1 
ATOM   9359  C  CA  . LEU D 1 208 ? 153.752 118.544 109.464 1.00 35.08  ? 155 LEU A CA  1 
ATOM   9360  C  C   . LEU D 1 208 ? 154.252 117.720 108.289 1.00 37.93  ? 155 LEU A C   1 
ATOM   9361  O  O   . LEU D 1 208 ? 155.405 117.864 107.875 1.00 39.27  ? 155 LEU A O   1 
ATOM   9362  C  CB  . LEU D 1 208 ? 153.905 120.039 109.197 1.00 33.85  ? 155 LEU A CB  1 
ATOM   9363  C  CG  . LEU D 1 208 ? 153.164 120.636 108.005 1.00 33.56  ? 155 LEU A CG  1 
ATOM   9364  C  CD1 . LEU D 1 208 ? 151.677 120.591 108.233 1.00 32.24  ? 155 LEU A CD1 1 
ATOM   9365  C  CD2 . LEU D 1 208 ? 153.619 122.051 107.773 1.00 31.59  ? 155 LEU A CD2 1 
ATOM   9366  N  N   . LYS D 1 209 ? 153.401 116.841 107.777 1.00 34.50  ? 156 LYS A N   1 
ATOM   9367  C  CA  . LYS D 1 209 ? 153.748 115.932 106.697 1.00 34.86  ? 156 LYS A CA  1 
ATOM   9368  C  C   . LYS D 1 209 ? 152.929 116.275 105.466 1.00 35.65  ? 156 LYS A C   1 
ATOM   9369  O  O   . LYS D 1 209 ? 151.734 116.551 105.569 1.00 41.09  ? 156 LYS A O   1 
ATOM   9370  C  CB  . LYS D 1 209 ? 153.482 114.482 107.094 1.00 34.32  ? 156 LYS A CB  1 
ATOM   9371  C  CG  . LYS D 1 209 ? 154.093 114.073 108.407 1.00 40.23  ? 156 LYS A CG  1 
ATOM   9372  C  CD  . LYS D 1 209 ? 153.562 112.733 108.854 1.00 43.78  ? 156 LYS A CD  1 
ATOM   9373  C  CE  . LYS D 1 209 ? 154.485 112.092 109.868 1.00 52.47  ? 156 LYS A CE  1 
ATOM   9374  N  NZ  . LYS D 1 209 ? 155.828 111.822 109.283 1.00 54.46  ? 156 LYS A NZ  1 
ATOM   9375  N  N   . PHE D 1 210 ? 153.567 116.263 104.301 1.00 32.23  ? 157 PHE A N   1 
ATOM   9376  C  CA  . PHE D 1 210 ? 152.810 116.505 103.083 1.00 30.96  ? 157 PHE A CA  1 
ATOM   9377  C  C   . PHE D 1 210 ? 153.376 115.672 101.944 1.00 35.83  ? 157 PHE A C   1 
ATOM   9378  O  O   . PHE D 1 210 ? 154.518 115.213 101.986 1.00 40.25  ? 157 PHE A O   1 
ATOM   9379  C  CB  . PHE D 1 210 ? 152.780 117.994 102.716 1.00 30.70  ? 157 PHE A CB  1 
ATOM   9380  C  CG  . PHE D 1 210 ? 154.121 118.577 102.374 1.00 34.81  ? 157 PHE A CG  1 
ATOM   9381  C  CD1 . PHE D 1 210 ? 154.910 119.143 103.349 1.00 33.54  ? 157 PHE A CD1 1 
ATOM   9382  C  CD2 . PHE D 1 210 ? 154.571 118.591 101.070 1.00 33.75  ? 157 PHE A CD2 1 
ATOM   9383  C  CE1 . PHE D 1 210 ? 156.124 119.689 103.034 1.00 31.81  ? 157 PHE A CE1 1 
ATOM   9384  C  CE2 . PHE D 1 210 ? 155.785 119.130 100.754 1.00 32.24  ? 157 PHE A CE2 1 
ATOM   9385  C  CZ  . PHE D 1 210 ? 156.560 119.684 101.735 1.00 34.38  ? 157 PHE A CZ  1 
ATOM   9386  N  N   . GLY D 1 211 ? 152.548 115.472 100.929 1.00 33.60  ? 158 GLY A N   1 
ATOM   9387  C  CA  . GLY D 1 211 ? 152.972 114.716 99.767  1.00 30.23  ? 158 GLY A CA  1 
ATOM   9388  C  C   . GLY D 1 211 ? 151.848 114.602 98.767  1.00 31.60  ? 158 GLY A C   1 
ATOM   9389  O  O   . GLY D 1 211 ? 150.761 115.150 98.951  1.00 33.08  ? 158 GLY A O   1 
ATOM   9390  N  N   . SER D 1 212 ? 152.133 113.881 97.690  1.00 33.92  ? 159 SER A N   1 
ATOM   9391  C  CA  . SER D 1 212 ? 151.147 113.667 96.641  1.00 31.66  ? 159 SER A CA  1 
ATOM   9392  C  C   . SER D 1 212 ? 150.028 112.761 97.131  1.00 33.97  ? 159 SER A C   1 
ATOM   9393  O  O   . SER D 1 212 ? 150.256 111.838 97.915  1.00 40.04  ? 159 SER A O   1 
ATOM   9394  C  CB  . SER D 1 212 ? 151.811 113.049 95.417  1.00 30.79  ? 159 SER A CB  1 
ATOM   9395  O  OG  . SER D 1 212 ? 150.874 112.839 94.382  1.00 32.69  ? 159 SER A OG  1 
ATOM   9396  N  N   . TYR D 1 213 ? 148.812 113.022 96.665  1.00 29.91  ? 160 TYR A N   1 
ATOM   9397  C  CA  . TYR D 1 213 ? 147.698 112.161 97.035  1.00 30.27  ? 160 TYR A CA  1 
ATOM   9398  C  C   . TYR D 1 213 ? 147.541 110.984 96.088  1.00 35.00  ? 160 TYR A C   1 
ATOM   9399  O  O   . TYR D 1 213 ? 147.319 109.859 96.539  1.00 39.56  ? 160 TYR A O   1 
ATOM   9400  C  CB  . TYR D 1 213 ? 146.388 112.951 97.090  1.00 27.73  ? 160 TYR A CB  1 
ATOM   9401  C  CG  . TYR D 1 213 ? 145.252 112.133 97.656  1.00 30.00  ? 160 TYR A CG  1 
ATOM   9402  C  CD1 . TYR D 1 213 ? 145.033 112.069 99.020  1.00 26.98  ? 160 TYR A CD1 1 
ATOM   9403  C  CD2 . TYR D 1 213 ? 144.419 111.402 96.828  1.00 31.94  ? 160 TYR A CD2 1 
ATOM   9404  C  CE1 . TYR D 1 213 ? 144.013 111.312 99.539  1.00 24.21  ? 160 TYR A CE1 1 
ATOM   9405  C  CE2 . TYR D 1 213 ? 143.402 110.639 97.340  1.00 31.80  ? 160 TYR A CE2 1 
ATOM   9406  C  CZ  . TYR D 1 213 ? 143.205 110.599 98.694  1.00 31.62  ? 160 TYR A CZ  1 
ATOM   9407  O  OH  . TYR D 1 213 ? 142.187 109.841 99.206  1.00 43.48  ? 160 TYR A OH  1 
ATOM   9408  N  N   . ALA D 1 214 ? 147.657 111.213 94.784  1.00 35.12  ? 161 ALA A N   1 
ATOM   9409  C  CA  . ALA D 1 214 ? 147.373 110.184 93.798  1.00 35.01  ? 161 ALA A CA  1 
ATOM   9410  C  C   . ALA D 1 214 ? 148.605 109.572 93.155  1.00 37.22  ? 161 ALA A C   1 
ATOM   9411  O  O   . ALA D 1 214 ? 148.574 108.393 92.811  1.00 40.97  ? 161 ALA A O   1 
ATOM   9412  C  CB  . ALA D 1 214 ? 146.472 110.743 92.693  1.00 37.55  ? 161 ALA A CB  1 
ATOM   9413  N  N   . TYR D 1 215 ? 149.687 110.323 92.993  1.00 38.47  ? 162 TYR A N   1 
ATOM   9414  C  CA  . TYR D 1 215 ? 150.839 109.847 92.242  1.00 40.20  ? 162 TYR A CA  1 
ATOM   9415  C  C   . TYR D 1 215 ? 151.872 109.239 93.178  1.00 42.43  ? 162 TYR A C   1 
ATOM   9416  O  O   . TYR D 1 215 ? 152.283 109.871 94.154  1.00 43.33  ? 162 TYR A O   1 
ATOM   9417  C  CB  . TYR D 1 215 ? 151.462 110.984 91.439  1.00 37.17  ? 162 TYR A CB  1 
ATOM   9418  C  CG  . TYR D 1 215 ? 150.541 111.603 90.416  1.00 37.83  ? 162 TYR A CG  1 
ATOM   9419  C  CD1 . TYR D 1 215 ? 150.374 111.031 89.170  1.00 36.62  ? 162 TYR A CD1 1 
ATOM   9420  C  CD2 . TYR D 1 215 ? 149.855 112.770 90.693  1.00 34.25  ? 162 TYR A CD2 1 
ATOM   9421  C  CE1 . TYR D 1 215 ? 149.546 111.594 88.238  1.00 39.93  ? 162 TYR A CE1 1 
ATOM   9422  C  CE2 . TYR D 1 215 ? 149.022 113.338 89.769  1.00 32.56  ? 162 TYR A CE2 1 
ATOM   9423  C  CZ  . TYR D 1 215 ? 148.871 112.748 88.542  1.00 38.86  ? 162 TYR A CZ  1 
ATOM   9424  O  OH  . TYR D 1 215 ? 148.041 113.319 87.614  1.00 49.24  ? 162 TYR A OH  1 
ATOM   9425  N  N   . THR D 1 216 ? 152.303 108.021 92.866  1.00 46.21  ? 163 THR A N   1 
ATOM   9426  C  CA  . THR D 1 216 ? 153.224 107.290 93.719  1.00 48.19  ? 163 THR A CA  1 
ATOM   9427  C  C   . THR D 1 216 ? 154.664 107.722 93.456  1.00 46.38  ? 163 THR A C   1 
ATOM   9428  O  O   . THR D 1 216 ? 154.943 108.591 92.629  1.00 47.65  ? 163 THR A O   1 
ATOM   9429  C  CB  . THR D 1 216 ? 153.051 105.788 93.514  1.00 48.59  ? 163 THR A CB  1 
ATOM   9430  O  OG1 . THR D 1 216 ? 153.301 105.456 92.145  1.00 55.68  ? 163 THR A OG1 1 
ATOM   9431  C  CG2 . THR D 1 216 ? 151.644 105.378 93.868  1.00 45.48  ? 163 THR A CG2 1 
ATOM   9432  N  N   . ARG D 1 217 ? 155.598 107.091 94.170  1.00 45.04  ? 164 ARG A N   1 
ATOM   9433  C  CA  . ARG D 1 217 ? 157.000 107.483 94.089  1.00 47.63  ? 164 ARG A CA  1 
ATOM   9434  C  C   . ARG D 1 217 ? 157.592 107.248 92.710  1.00 48.71  ? 164 ARG A C   1 
ATOM   9435  O  O   . ARG D 1 217 ? 158.600 107.873 92.366  1.00 45.83  ? 164 ARG A O   1 
ATOM   9436  C  CB  . ARG D 1 217 ? 157.816 106.719 95.124  1.00 47.98  ? 164 ARG A CB  1 
ATOM   9437  C  CG  . ARG D 1 217 ? 157.851 105.228 94.875  1.00 56.92  ? 164 ARG A CG  1 
ATOM   9438  C  CD  . ARG D 1 217 ? 158.853 104.544 95.776  1.00 60.96  ? 164 ARG A CD  1 
ATOM   9439  N  NE  . ARG D 1 217 ? 160.171 105.153 95.666  1.00 67.40  ? 164 ARG A NE  1 
ATOM   9440  C  CZ  . ARG D 1 217 ? 161.194 104.863 96.456  1.00 75.00  ? 164 ARG A CZ  1 
ATOM   9441  N  NH1 . ARG D 1 217 ? 161.086 103.967 97.422  1.00 73.92  ? 164 ARG A NH1 1 
ATOM   9442  N  NH2 . ARG D 1 217 ? 162.352 105.489 96.274  1.00 73.08  ? 164 ARG A NH2 1 
ATOM   9443  N  N   . ALA D 1 218 ? 156.998 106.365 91.916  1.00 48.82  ? 165 ALA A N   1 
ATOM   9444  C  CA  . ALA D 1 218 ? 157.471 106.110 90.564  1.00 50.18  ? 165 ALA A CA  1 
ATOM   9445  C  C   . ALA D 1 218 ? 156.945 107.118 89.558  1.00 48.53  ? 165 ALA A C   1 
ATOM   9446  O  O   . ALA D 1 218 ? 157.284 107.024 88.377  1.00 50.93  ? 165 ALA A O   1 
ATOM   9447  C  CB  . ALA D 1 218 ? 157.084 104.697 90.130  1.00 54.32  ? 165 ALA A CB  1 
ATOM   9448  N  N   . GLU D 1 219 ? 156.117 108.061 89.992  1.00 47.96  ? 166 GLU A N   1 
ATOM   9449  C  CA  . GLU D 1 219 ? 155.568 109.091 89.123  1.00 45.66  ? 166 GLU A CA  1 
ATOM   9450  C  C   . GLU D 1 219 ? 155.934 110.495 89.571  1.00 44.93  ? 166 GLU A C   1 
ATOM   9451  O  O   . GLU D 1 219 ? 156.381 111.302 88.753  1.00 46.36  ? 166 GLU A O   1 
ATOM   9452  C  CB  . GLU D 1 219 ? 154.047 108.948 89.047  1.00 48.62  ? 166 GLU A CB  1 
ATOM   9453  C  CG  . GLU D 1 219 ? 153.600 107.702 88.321  1.00 56.29  ? 166 GLU A CG  1 
ATOM   9454  C  CD  . GLU D 1 219 ? 152.100 107.608 88.212  1.00 69.83  ? 166 GLU A CD  1 
ATOM   9455  O  OE1 . GLU D 1 219 ? 151.418 107.841 89.230  1.00 70.81  ? 166 GLU A OE1 1 
ATOM   9456  O  OE2 . GLU D 1 219 ? 151.600 107.312 87.108  1.00 75.88  ? 166 GLU A OE2 1 
ATOM   9457  N  N   . VAL D 1 220 ? 155.753 110.813 90.848  1.00 43.28  ? 167 VAL A N   1 
ATOM   9458  C  CA  . VAL D 1 220 ? 156.021 112.143 91.378  1.00 39.45  ? 167 VAL A CA  1 
ATOM   9459  C  C   . VAL D 1 220 ? 156.888 112.002 92.618  1.00 42.64  ? 167 VAL A C   1 
ATOM   9460  O  O   . VAL D 1 220 ? 156.566 111.220 93.517  1.00 46.06  ? 167 VAL A O   1 
ATOM   9461  C  CB  . VAL D 1 220 ? 154.717 112.893 91.709  1.00 34.06  ? 167 VAL A CB  1 
ATOM   9462  C  CG1 . VAL D 1 220 ? 155.003 114.140 92.507  1.00 28.04  ? 167 VAL A CG1 1 
ATOM   9463  C  CG2 . VAL D 1 220 ? 153.979 113.251 90.440  1.00 36.55  ? 167 VAL A CG2 1 
ATOM   9464  N  N   . VAL D 1 221 ? 157.983 112.755 92.664  1.00 43.72  ? 168 VAL A N   1 
ATOM   9465  C  CA  . VAL D 1 221 ? 158.836 112.828 93.840  1.00 43.23  ? 168 VAL A CA  1 
ATOM   9466  C  C   . VAL D 1 221 ? 158.929 114.286 94.259  1.00 41.11  ? 168 VAL A C   1 
ATOM   9467  O  O   . VAL D 1 221 ? 158.710 115.200 93.464  1.00 43.53  ? 168 VAL A O   1 
ATOM   9468  C  CB  . VAL D 1 221 ? 160.241 112.242 93.597  1.00 41.91  ? 168 VAL A CB  1 
ATOM   9469  C  CG1 . VAL D 1 221 ? 160.142 110.806 93.132  1.00 42.85  ? 168 VAL A CG1 1 
ATOM   9470  C  CG2 . VAL D 1 221 ? 160.998 113.075 92.593  1.00 44.63  ? 168 VAL A CG2 1 
ATOM   9471  N  N   . TYR D 1 222 ? 159.254 114.496 95.528  1.00 37.27  ? 169 TYR A N   1 
ATOM   9472  C  CA  . TYR D 1 222 ? 159.354 115.831 96.096  1.00 36.46  ? 169 TYR A CA  1 
ATOM   9473  C  C   . TYR D 1 222 ? 160.752 116.065 96.643  1.00 41.87  ? 169 TYR A C   1 
ATOM   9474  O  O   . TYR D 1 222 ? 161.372 115.158 97.203  1.00 49.39  ? 169 TYR A O   1 
ATOM   9475  C  CB  . TYR D 1 222 ? 158.331 116.040 97.205  1.00 35.12  ? 169 TYR A CB  1 
ATOM   9476  C  CG  . TYR D 1 222 ? 156.919 116.248 96.729  1.00 39.44  ? 169 TYR A CG  1 
ATOM   9477  C  CD1 . TYR D 1 222 ? 156.140 115.179 96.327  1.00 36.36  ? 169 TYR A CD1 1 
ATOM   9478  C  CD2 . TYR D 1 222 ? 156.353 117.509 96.714  1.00 41.18  ? 169 TYR A CD2 1 
ATOM   9479  C  CE1 . TYR D 1 222 ? 154.849 115.365 95.902  1.00 33.48  ? 169 TYR A CE1 1 
ATOM   9480  C  CE2 . TYR D 1 222 ? 155.059 117.703 96.293  1.00 34.90  ? 169 TYR A CE2 1 
ATOM   9481  C  CZ  . TYR D 1 222 ? 154.314 116.628 95.888  1.00 33.44  ? 169 TYR A CZ  1 
ATOM   9482  O  OH  . TYR D 1 222 ? 153.024 116.822 95.469  1.00 34.55  ? 169 TYR A OH  1 
ATOM   9483  N  N   . GLU D 1 223 ? 161.247 117.283 96.465  1.00 43.52  ? 170 GLU A N   1 
ATOM   9484  C  CA  . GLU D 1 223 ? 162.539 117.704 96.977  1.00 45.47  ? 170 GLU A CA  1 
ATOM   9485  C  C   . GLU D 1 223 ? 162.373 119.049 97.661  1.00 44.87  ? 170 GLU A C   1 
ATOM   9486  O  O   . GLU D 1 223 ? 161.312 119.669 97.598  1.00 49.11  ? 170 GLU A O   1 
ATOM   9487  C  CB  . GLU D 1 223 ? 163.580 117.793 95.858  1.00 46.87  ? 170 GLU A CB  1 
ATOM   9488  C  CG  . GLU D 1 223 ? 163.785 116.488 95.126  1.00 61.56  ? 170 GLU A CG  1 
ATOM   9489  C  CD  . GLU D 1 223 ? 164.737 116.618 93.958  1.00 86.97  ? 170 GLU A CD  1 
ATOM   9490  O  OE1 . GLU D 1 223 ? 165.117 117.759 93.626  1.00 89.14  ? 170 GLU A OE1 1 
ATOM   9491  O  OE2 . GLU D 1 223 ? 165.104 115.578 93.372  1.00 91.45  ? 170 GLU A OE2 1 
ATOM   9492  N  N   . TRP D 1 224 ? 163.424 119.503 98.328  1.00 41.68  ? 171 TRP A N   1 
ATOM   9493  C  CA  . TRP D 1 224 ? 163.434 120.835 98.910  1.00 43.38  ? 171 TRP A CA  1 
ATOM   9494  C  C   . TRP D 1 224 ? 164.155 121.789 97.967  1.00 50.69  ? 171 TRP A C   1 
ATOM   9495  O  O   . TRP D 1 224 ? 165.135 121.414 97.321  1.00 58.63  ? 171 TRP A O   1 
ATOM   9496  C  CB  . TRP D 1 224 ? 164.097 120.839 100.287 1.00 42.49  ? 171 TRP A CB  1 
ATOM   9497  C  CG  . TRP D 1 224 ? 163.387 120.016 101.328 1.00 41.68  ? 171 TRP A CG  1 
ATOM   9498  C  CD1 . TRP D 1 224 ? 163.781 118.811 101.818 1.00 44.93  ? 171 TRP A CD1 1 
ATOM   9499  C  CD2 . TRP D 1 224 ? 162.167 120.342 102.007 1.00 39.51  ? 171 TRP A CD2 1 
ATOM   9500  N  NE1 . TRP D 1 224 ? 162.890 118.365 102.758 1.00 43.41  ? 171 TRP A NE1 1 
ATOM   9501  C  CE2 . TRP D 1 224 ? 161.888 119.286 102.891 1.00 37.99  ? 171 TRP A CE2 1 
ATOM   9502  C  CE3 . TRP D 1 224 ? 161.284 121.421 101.952 1.00 39.32  ? 171 TRP A CE3 1 
ATOM   9503  C  CZ2 . TRP D 1 224 ? 160.768 119.278 103.710 1.00 32.10  ? 171 TRP A CZ2 1 
ATOM   9504  C  CZ3 . TRP D 1 224 ? 160.172 121.410 102.770 1.00 35.92  ? 171 TRP A CZ3 1 
ATOM   9505  C  CH2 . TRP D 1 224 ? 159.928 120.348 103.637 1.00 30.81  ? 171 TRP A CH2 1 
ATOM   9506  N  N   . THR D 1 225 ? 163.661 123.027 97.893  1.00 48.04  ? 172 THR A N   1 
ATOM   9507  C  CA  . THR D 1 225 ? 164.188 123.987 96.930  1.00 50.92  ? 172 THR A CA  1 
ATOM   9508  C  C   . THR D 1 225 ? 165.671 124.247 97.145  1.00 60.60  ? 172 THR A C   1 
ATOM   9509  O  O   . THR D 1 225 ? 166.400 124.529 96.189  1.00 62.93  ? 172 THR A O   1 
ATOM   9510  C  CB  . THR D 1 225 ? 163.418 125.300 97.029  1.00 51.75  ? 172 THR A CB  1 
ATOM   9511  O  OG1 . THR D 1 225 ? 162.018 125.026 97.119  1.00 55.57  ? 172 THR A OG1 1 
ATOM   9512  C  CG2 . THR D 1 225 ? 163.670 126.158 95.810  1.00 54.12  ? 172 THR A CG2 1 
ATOM   9513  N  N   . ARG D 1 226 ? 166.129 124.160 98.386  1.00 63.43  ? 173 ARG A N   1 
ATOM   9514  C  CA  . ARG D 1 226 ? 167.506 124.465 98.746  1.00 67.35  ? 173 ARG A CA  1 
ATOM   9515  C  C   . ARG D 1 226 ? 167.921 123.437 99.789  1.00 69.02  ? 173 ARG A C   1 
ATOM   9516  O  O   . ARG D 1 226 ? 167.357 122.340 99.860  1.00 67.73  ? 173 ARG A O   1 
ATOM   9517  C  CB  . ARG D 1 226 ? 167.633 125.924 99.210  1.00 65.38  ? 173 ARG A CB  1 
ATOM   9518  C  CG  . ARG D 1 226 ? 166.725 126.300 100.357 1.00 61.99  ? 173 ARG A CG  1 
ATOM   9519  C  CD  . ARG D 1 226 ? 166.679 127.802 100.543 1.00 66.13  ? 173 ARG A CD  1 
ATOM   9520  N  NE  . ARG D 1 226 ? 165.872 128.464 99.527  1.00 69.06  ? 173 ARG A NE  1 
ATOM   9521  C  CZ  . ARG D 1 226 ? 164.661 128.962 99.737  1.00 68.51  ? 173 ARG A CZ  1 
ATOM   9522  N  NH1 . ARG D 1 226 ? 164.084 128.903 100.925 1.00 62.31  ? 173 ARG A NH1 1 
ATOM   9523  N  NH2 . ARG D 1 226 ? 164.015 129.542 98.731  1.00 69.26  ? 173 ARG A NH2 1 
ATOM   9524  N  N   . GLU D 1 227 ? 168.947 123.751 100.568 1.00 72.21  ? 174 GLU A N   1 
ATOM   9525  C  CA  . GLU D 1 227 ? 169.309 122.877 101.672 1.00 70.19  ? 174 GLU A CA  1 
ATOM   9526  C  C   . GLU D 1 227 ? 168.104 122.695 102.590 1.00 68.20  ? 174 GLU A C   1 
ATOM   9527  O  O   . GLU D 1 227 ? 167.387 123.663 102.868 1.00 67.88  ? 174 GLU A O   1 
ATOM   9528  C  CB  . GLU D 1 227 ? 170.488 123.449 102.459 1.00 74.32  ? 174 GLU A CB  1 
ATOM   9529  C  CG  . GLU D 1 227 ? 171.775 123.562 101.663 1.00 86.33  ? 174 GLU A CG  1 
ATOM   9530  C  CD  . GLU D 1 227 ? 171.782 124.748 100.719 1.00 94.89  ? 174 GLU A CD  1 
ATOM   9531  O  OE1 . GLU D 1 227 ? 171.121 125.760 101.031 1.00 91.80  ? 174 GLU A OE1 1 
ATOM   9532  O  OE2 . GLU D 1 227 ? 172.441 124.665 99.661  1.00 99.50  ? 174 GLU A OE2 1 
ATOM   9533  N  N   . PRO D 1 228 ? 167.842 121.474 103.061 1.00 65.91  ? 175 PRO A N   1 
ATOM   9534  C  CA  . PRO D 1 228 ? 166.600 121.223 103.808 1.00 60.11  ? 175 PRO A CA  1 
ATOM   9535  C  C   . PRO D 1 228 ? 166.431 122.097 105.034 1.00 60.44  ? 175 PRO A C   1 
ATOM   9536  O  O   . PRO D 1 228 ? 165.301 122.483 105.354 1.00 58.79  ? 175 PRO A O   1 
ATOM   9537  C  CB  . PRO D 1 228 ? 166.725 119.743 104.187 1.00 57.07  ? 175 PRO A CB  1 
ATOM   9538  C  CG  . PRO D 1 228 ? 167.638 119.173 103.174 1.00 58.99  ? 175 PRO A CG  1 
ATOM   9539  C  CD  . PRO D 1 228 ? 168.630 120.247 102.880 1.00 64.79  ? 175 PRO A CD  1 
ATOM   9540  N  N   . ALA D 1 229 ? 167.518 122.425 105.732 1.00 61.61  ? 176 ALA A N   1 
ATOM   9541  C  CA  . ALA D 1 229 ? 167.412 123.244 106.932 1.00 58.51  ? 176 ALA A CA  1 
ATOM   9542  C  C   . ALA D 1 229 ? 166.962 124.662 106.628 1.00 59.53  ? 176 ALA A C   1 
ATOM   9543  O  O   . ALA D 1 229 ? 166.454 125.340 107.525 1.00 62.42  ? 176 ALA A O   1 
ATOM   9544  C  CB  . ALA D 1 229 ? 168.749 123.279 107.668 1.00 61.36  ? 176 ALA A CB  1 
ATOM   9545  N  N   . ARG D 1 230 ? 167.139 125.125 105.394 1.00 60.75  ? 177 ARG A N   1 
ATOM   9546  C  CA  . ARG D 1 230 ? 166.755 126.473 105.005 1.00 60.15  ? 177 ARG A CA  1 
ATOM   9547  C  C   . ARG D 1 230 ? 165.574 126.497 104.048 1.00 58.69  ? 177 ARG A C   1 
ATOM   9548  O  O   . ARG D 1 230 ? 165.282 127.546 103.469 1.00 60.09  ? 177 ARG A O   1 
ATOM   9549  C  CB  . ARG D 1 230 ? 167.946 127.201 104.383 1.00 67.04  ? 177 ARG A CB  1 
ATOM   9550  C  CG  . ARG D 1 230 ? 169.180 127.220 105.262 1.00 72.70  ? 177 ARG A CG  1 
ATOM   9551  C  CD  . ARG D 1 230 ? 170.235 128.179 104.738 1.00 81.95  ? 177 ARG A CD  1 
ATOM   9552  N  NE  . ARG D 1 230 ? 170.516 127.983 103.321 1.00 89.15  ? 177 ARG A NE  1 
ATOM   9553  C  CZ  . ARG D 1 230 ? 170.088 128.782 102.354 1.00 89.44  ? 177 ARG A CZ  1 
ATOM   9554  N  NH1 . ARG D 1 230 ? 169.356 129.853 102.615 1.00 85.14  ? 177 ARG A NH1 1 
ATOM   9555  N  NH2 . ARG D 1 230 ? 170.402 128.501 101.093 1.00 87.46  ? 177 ARG A NH2 1 
ATOM   9556  N  N   . SER D 1 231 ? 164.897 125.368 103.852 1.00 57.00  ? 178 SER A N   1 
ATOM   9557  C  CA  . SER D 1 231 ? 163.723 125.327 102.995 1.00 48.09  ? 178 SER A CA  1 
ATOM   9558  C  C   . SER D 1 231 ? 162.424 125.531 103.752 1.00 42.18  ? 178 SER A C   1 
ATOM   9559  O  O   . SER D 1 231 ? 161.373 125.644 103.117 1.00 48.39  ? 178 SER A O   1 
ATOM   9560  C  CB  . SER D 1 231 ? 163.670 124.005 102.237 1.00 49.23  ? 178 SER A CB  1 
ATOM   9561  O  OG  . SER D 1 231 ? 164.746 123.923 101.327 1.00 57.00  ? 178 SER A OG  1 
ATOM   9562  N  N   . VAL D 1 232 ? 162.461 125.582 105.078 1.00 39.94  ? 179 VAL A N   1 
ATOM   9563  C  CA  . VAL D 1 232 ? 161.314 125.952 105.896 1.00 41.14  ? 179 VAL A CA  1 
ATOM   9564  C  C   . VAL D 1 232 ? 161.747 127.141 106.736 1.00 44.19  ? 179 VAL A C   1 
ATOM   9565  O  O   . VAL D 1 232 ? 162.528 126.986 107.681 1.00 47.38  ? 179 VAL A O   1 
ATOM   9566  C  CB  . VAL D 1 232 ? 160.834 124.795 106.780 1.00 40.08  ? 179 VAL A CB  1 
ATOM   9567  C  CG1 . VAL D 1 232 ? 159.747 125.261 107.718 1.00 36.33  ? 179 VAL A CG1 1 
ATOM   9568  C  CG2 . VAL D 1 232 ? 160.326 123.662 105.927 1.00 42.75  ? 179 VAL A CG2 1 
ATOM   9569  N  N   . VAL D 1 233 ? 161.246 128.328 106.404 1.00 40.59  ? 180 VAL A N   1 
ATOM   9570  C  CA  . VAL D 1 233 ? 161.695 129.570 107.023 1.00 35.30  ? 180 VAL A CA  1 
ATOM   9571  C  C   . VAL D 1 233 ? 160.537 130.174 107.798 1.00 36.88  ? 180 VAL A C   1 
ATOM   9572  O  O   . VAL D 1 233 ? 159.430 130.290 107.269 1.00 40.29  ? 180 VAL A O   1 
ATOM   9573  C  CB  . VAL D 1 233 ? 162.230 130.564 105.980 1.00 33.94  ? 180 VAL A CB  1 
ATOM   9574  C  CG1 . VAL D 1 233 ? 162.529 131.888 106.630 1.00 37.35  ? 180 VAL A CG1 1 
ATOM   9575  C  CG2 . VAL D 1 233 ? 163.471 130.013 105.322 1.00 39.18  ? 180 VAL A CG2 1 
ATOM   9576  N  N   . VAL D 1 234 ? 160.794 130.559 109.043 1.00 38.26  ? 181 VAL A N   1 
ATOM   9577  C  CA  . VAL D 1 234 ? 159.779 131.108 109.933 1.00 37.89  ? 181 VAL A CA  1 
ATOM   9578  C  C   . VAL D 1 234 ? 159.952 132.618 110.018 1.00 43.90  ? 181 VAL A C   1 
ATOM   9579  O  O   . VAL D 1 234 ? 161.070 133.112 110.195 1.00 50.25  ? 181 VAL A O   1 
ATOM   9580  C  CB  . VAL D 1 234 ? 159.865 130.469 111.327 1.00 38.84  ? 181 VAL A CB  1 
ATOM   9581  C  CG1 . VAL D 1 234 ? 158.676 130.876 112.168 1.00 33.75  ? 181 VAL A CG1 1 
ATOM   9582  C  CG2 . VAL D 1 234 ? 159.950 128.964 111.207 1.00 39.07  ? 181 VAL A CG2 1 
ATOM   9583  N  N   . ALA D 1 235 ? 158.846 133.349 109.904 1.00 47.92  ? 182 ALA A N   1 
ATOM   9584  C  CA  . ALA D 1 235 ? 158.885 134.804 109.944 1.00 51.63  ? 182 ALA A CA  1 
ATOM   9585  C  C   . ALA D 1 235 ? 159.323 135.307 111.315 1.00 65.73  ? 182 ALA A C   1 
ATOM   9586  O  O   . ALA D 1 235 ? 159.104 134.659 112.340 1.00 70.35  ? 182 ALA A O   1 
ATOM   9587  C  CB  . ALA D 1 235 ? 157.517 135.381 109.594 1.00 46.28  ? 182 ALA A CB  1 
ATOM   9588  N  N   . GLU D 1 236 ? 159.939 136.492 111.322 1.00 72.53  ? 183 GLU A N   1 
ATOM   9589  C  CA  . GLU D 1 236 ? 160.546 137.020 112.542 1.00 81.89  ? 183 GLU A CA  1 
ATOM   9590  C  C   . GLU D 1 236 ? 159.504 137.298 113.618 1.00 83.66  ? 183 GLU A C   1 
ATOM   9591  O  O   . GLU D 1 236 ? 159.688 136.928 114.782 1.00 86.42  ? 183 GLU A O   1 
ATOM   9592  C  CB  . GLU D 1 236 ? 161.338 138.285 112.221 1.00 87.60  ? 183 GLU A CB  1 
ATOM   9593  C  CG  . GLU D 1 236 ? 162.477 138.068 111.245 1.00 97.26  ? 183 GLU A CG  1 
ATOM   9594  C  CD  . GLU D 1 236 ? 163.109 139.369 110.786 1.00 112.66 ? 183 GLU A CD  1 
ATOM   9595  O  OE1 . GLU D 1 236 ? 162.591 140.445 111.151 1.00 110.77 ? 183 GLU A OE1 1 
ATOM   9596  O  OE2 . GLU D 1 236 ? 164.123 139.315 110.058 1.00 119.36 ? 183 GLU A OE2 1 
ATOM   9597  N  N   . ASP D 1 237 ? 158.403 137.950 113.254 1.00 81.05  ? 184 ASP A N   1 
ATOM   9598  C  CA  . ASP D 1 237 ? 157.331 138.250 114.201 1.00 85.17  ? 184 ASP A CA  1 
ATOM   9599  C  C   . ASP D 1 237 ? 156.132 137.338 114.002 1.00 85.29  ? 184 ASP A C   1 
ATOM   9600  O  O   . ASP D 1 237 ? 154.985 137.755 114.171 1.00 85.46  ? 184 ASP A O   1 
ATOM   9601  C  CB  . ASP D 1 237 ? 156.912 139.710 114.085 1.00 93.84  ? 184 ASP A CB  1 
ATOM   9602  C  CG  . ASP D 1 237 ? 157.891 140.650 114.751 1.00 102.93 ? 184 ASP A CG  1 
ATOM   9603  O  OD1 . ASP D 1 237 ? 159.020 140.214 115.056 1.00 105.84 ? 184 ASP A OD1 1 
ATOM   9604  O  OD2 . ASP D 1 237 ? 157.528 141.824 114.978 1.00 104.13 ? 184 ASP A OD2 1 
ATOM   9605  N  N   . GLY D 1 238 ? 156.371 136.086 113.639 1.00 80.99  ? 185 GLY A N   1 
ATOM   9606  C  CA  . GLY D 1 238 ? 155.288 135.189 113.306 1.00 66.94  ? 185 GLY A CA  1 
ATOM   9607  C  C   . GLY D 1 238 ? 154.974 134.199 114.401 1.00 62.07  ? 185 GLY A C   1 
ATOM   9608  O  O   . GLY D 1 238 ? 154.742 133.020 114.128 1.00 65.94  ? 185 GLY A O   1 
ATOM   9609  N  N   . SER D 1 239 ? 154.972 134.655 115.645 1.00 62.29  ? 186 SER A N   1 
ATOM   9610  C  CA  . SER D 1 239 ? 154.669 133.803 116.783 1.00 58.43  ? 186 SER A CA  1 
ATOM   9611  C  C   . SER D 1 239 ? 153.314 134.204 117.345 1.00 53.71  ? 186 SER A C   1 
ATOM   9612  O  O   . SER D 1 239 ? 153.136 135.337 117.800 1.00 58.63  ? 186 SER A O   1 
ATOM   9613  C  CB  . SER D 1 239 ? 155.750 133.912 117.854 1.00 62.82  ? 186 SER A CB  1 
ATOM   9614  O  OG  . SER D 1 239 ? 155.590 132.911 118.842 1.00 59.86  ? 186 SER A OG  1 
ATOM   9615  N  N   . ARG D 1 240 ? 152.361 133.280 117.294 1.00 45.80  ? 187 ARG A N   1 
ATOM   9616  C  CA  . ARG D 1 240 ? 151.070 133.444 117.941 1.00 43.70  ? 187 ARG A CA  1 
ATOM   9617  C  C   . ARG D 1 240 ? 150.930 132.493 119.122 1.00 42.67  ? 187 ARG A C   1 
ATOM   9618  O  O   . ARG D 1 240 ? 149.834 132.021 119.424 1.00 39.81  ? 187 ARG A O   1 
ATOM   9619  C  CB  . ARG D 1 240 ? 149.935 133.229 116.945 1.00 43.43  ? 187 ARG A CB  1 
ATOM   9620  C  CG  . ARG D 1 240 ? 149.965 134.160 115.759 1.00 43.80  ? 187 ARG A CG  1 
ATOM   9621  C  CD  . ARG D 1 240 ? 148.775 133.912 114.859 1.00 45.66  ? 187 ARG A CD  1 
ATOM   9622  N  NE  . ARG D 1 240 ? 148.729 134.842 113.737 1.00 53.55  ? 187 ARG A NE  1 
ATOM   9623  C  CZ  . ARG D 1 240 ? 147.814 134.810 112.779 1.00 49.48  ? 187 ARG A CZ  1 
ATOM   9624  N  NH1 . ARG D 1 240 ? 146.856 133.900 112.770 1.00 50.95  ? 187 ARG A NH1 1 
ATOM   9625  N  NH2 . ARG D 1 240 ? 147.863 135.711 111.804 1.00 43.94  ? 187 ARG A NH2 1 
ATOM   9626  N  N   . LEU D 1 241 ? 152.041 132.205 119.792 1.00 46.31  ? 188 LEU A N   1 
ATOM   9627  C  CA  . LEU D 1 241 ? 152.085 131.256 120.894 1.00 46.13  ? 188 LEU A CA  1 
ATOM   9628  C  C   . LEU D 1 241 ? 151.991 131.994 122.220 1.00 49.19  ? 188 LEU A C   1 
ATOM   9629  O  O   . LEU D 1 241 ? 152.706 132.975 122.442 1.00 51.03  ? 188 LEU A O   1 
ATOM   9630  C  CB  . LEU D 1 241 ? 153.372 130.435 120.842 1.00 41.84  ? 188 LEU A CB  1 
ATOM   9631  C  CG  . LEU D 1 241 ? 153.473 129.437 119.699 1.00 35.57  ? 188 LEU A CG  1 
ATOM   9632  C  CD1 . LEU D 1 241 ? 154.894 128.960 119.532 1.00 36.55  ? 188 LEU A CD1 1 
ATOM   9633  C  CD2 . LEU D 1 241 ? 152.557 128.277 119.978 1.00 33.74  ? 188 LEU A CD2 1 
ATOM   9634  N  N   . ASN D 1 242 ? 151.116 131.517 123.099 1.00 46.47  ? 189 ASN A N   1 
ATOM   9635  C  CA  . ASN D 1 242 ? 150.953 132.112 124.417 1.00 46.76  ? 189 ASN A CA  1 
ATOM   9636  C  C   . ASN D 1 242 ? 151.631 131.320 125.518 1.00 54.40  ? 189 ASN A C   1 
ATOM   9637  O  O   . ASN D 1 242 ? 152.127 131.918 126.475 1.00 59.69  ? 189 ASN A O   1 
ATOM   9638  C  CB  . ASN D 1 242 ? 149.470 132.250 124.767 1.00 44.81  ? 189 ASN A CB  1 
ATOM   9639  C  CG  . ASN D 1 242 ? 148.778 133.306 123.954 1.00 52.38  ? 189 ASN A CG  1 
ATOM   9640  O  OD1 . ASN D 1 242 ? 149.256 134.432 123.840 1.00 59.94  ? 189 ASN A OD1 1 
ATOM   9641  N  ND2 . ASN D 1 242 ? 147.641 132.950 123.378 1.00 53.80  ? 189 ASN A ND2 1 
ATOM   9642  N  N   . GLN D 1 243 ? 151.668 129.995 125.414 1.00 49.90  ? 190 GLN A N   1 
ATOM   9643  C  CA  . GLN D 1 243 ? 152.235 129.167 126.468 1.00 45.54  ? 190 GLN A CA  1 
ATOM   9644  C  C   . GLN D 1 243 ? 153.365 128.279 125.970 1.00 46.43  ? 190 GLN A C   1 
ATOM   9645  O  O   . GLN D 1 243 ? 153.741 127.331 126.658 1.00 53.92  ? 190 GLN A O   1 
ATOM   9646  C  CB  . GLN D 1 243 ? 151.143 128.322 127.120 1.00 46.94  ? 190 GLN A CB  1 
ATOM   9647  C  CG  . GLN D 1 243 ? 150.085 127.830 126.161 1.00 52.08  ? 190 GLN A CG  1 
ATOM   9648  C  CD  . GLN D 1 243 ? 149.032 126.986 126.848 1.00 70.42  ? 190 GLN A CD  1 
ATOM   9649  O  OE1 . GLN D 1 243 ? 149.224 126.531 127.974 1.00 76.96  ? 190 GLN A OE1 1 
ATOM   9650  N  NE2 . GLN D 1 243 ? 147.912 126.773 126.174 1.00 72.17  ? 190 GLN A NE2 1 
ATOM   9651  N  N   . TYR D 1 244 ? 153.931 128.575 124.803 1.00 44.74  ? 191 TYR A N   1 
ATOM   9652  C  CA  . TYR D 1 244 ? 155.019 127.780 124.257 1.00 39.59  ? 191 TYR A CA  1 
ATOM   9653  C  C   . TYR D 1 244 ? 156.082 128.697 123.674 1.00 44.14  ? 191 TYR A C   1 
ATOM   9654  O  O   . TYR D 1 244 ? 155.833 129.869 123.388 1.00 49.98  ? 191 TYR A O   1 
ATOM   9655  C  CB  . TYR D 1 244 ? 154.538 126.816 123.174 1.00 40.05  ? 191 TYR A CB  1 
ATOM   9656  C  CG  . TYR D 1 244 ? 153.559 125.772 123.632 1.00 42.46  ? 191 TYR A CG  1 
ATOM   9657  C  CD1 . TYR D 1 244 ? 152.198 126.015 123.596 1.00 44.79  ? 191 TYR A CD1 1 
ATOM   9658  C  CD2 . TYR D 1 244 ? 153.992 124.534 124.069 1.00 39.23  ? 191 TYR A CD2 1 
ATOM   9659  C  CE1 . TYR D 1 244 ? 151.301 125.065 123.996 1.00 43.50  ? 191 TYR A CE1 1 
ATOM   9660  C  CE2 . TYR D 1 244 ? 153.103 123.581 124.473 1.00 38.75  ? 191 TYR A CE2 1 
ATOM   9661  C  CZ  . TYR D 1 244 ? 151.758 123.853 124.434 1.00 43.56  ? 191 TYR A CZ  1 
ATOM   9662  O  OH  . TYR D 1 244 ? 150.860 122.904 124.838 1.00 50.50  ? 191 TYR A OH  1 
ATOM   9663  N  N   . ASP D 1 245 ? 157.279 128.143 123.505 1.00 44.91  ? 192 ASP A N   1 
ATOM   9664  C  CA  . ASP D 1 245 ? 158.360 128.775 122.761 1.00 48.43  ? 192 ASP A CA  1 
ATOM   9665  C  C   . ASP D 1 245 ? 158.687 127.899 121.565 1.00 48.34  ? 192 ASP A C   1 
ATOM   9666  O  O   . ASP D 1 245 ? 158.785 126.678 121.701 1.00 51.02  ? 192 ASP A O   1 
ATOM   9667  C  CB  . ASP D 1 245 ? 159.616 128.949 123.617 1.00 54.00  ? 192 ASP A CB  1 
ATOM   9668  C  CG  . ASP D 1 245 ? 159.349 129.676 124.907 1.00 64.22  ? 192 ASP A CG  1 
ATOM   9669  O  OD1 . ASP D 1 245 ? 158.543 130.626 124.899 1.00 65.09  ? 192 ASP A OD1 1 
ATOM   9670  O  OD2 . ASP D 1 245 ? 159.951 129.298 125.933 1.00 69.91  ? 192 ASP A OD2 1 
ATOM   9671  N  N   . LEU D 1 246 ? 158.849 128.513 120.398 1.00 48.88  ? 193 LEU A N   1 
ATOM   9672  C  CA  . LEU D 1 246 ? 159.244 127.786 119.194 1.00 44.60  ? 193 LEU A CA  1 
ATOM   9673  C  C   . LEU D 1 246 ? 160.763 127.720 119.170 1.00 43.91  ? 193 LEU A C   1 
ATOM   9674  O  O   . LEU D 1 246 ? 161.431 128.678 118.782 1.00 46.46  ? 193 LEU A O   1 
ATOM   9675  C  CB  . LEU D 1 246 ? 158.692 128.463 117.946 1.00 43.99  ? 193 LEU A CB  1 
ATOM   9676  C  CG  . LEU D 1 246 ? 158.990 127.789 116.609 1.00 42.71  ? 193 LEU A CG  1 
ATOM   9677  C  CD1 . LEU D 1 246 ? 158.391 126.409 116.561 1.00 38.41  ? 193 LEU A CD1 1 
ATOM   9678  C  CD2 . LEU D 1 246 ? 158.468 128.629 115.472 1.00 45.08  ? 193 LEU A CD2 1 
ATOM   9679  N  N   . LEU D 1 247 ? 161.316 126.592 119.614 1.00 43.59  ? 194 LEU A N   1 
ATOM   9680  C  CA  . LEU D 1 247 ? 162.766 126.456 119.669 1.00 41.86  ? 194 LEU A CA  1 
ATOM   9681  C  C   . LEU D 1 247 ? 163.376 126.399 118.275 1.00 45.99  ? 194 LEU A C   1 
ATOM   9682  O  O   . LEU D 1 247 ? 164.455 126.953 118.040 1.00 50.74  ? 194 LEU A O   1 
ATOM   9683  C  CB  . LEU D 1 247 ? 163.144 125.211 120.464 1.00 41.80  ? 194 LEU A CB  1 
ATOM   9684  C  CG  . LEU D 1 247 ? 162.656 125.150 121.908 1.00 46.94  ? 194 LEU A CG  1 
ATOM   9685  C  CD1 . LEU D 1 247 ? 163.104 123.852 122.544 1.00 49.37  ? 194 LEU A CD1 1 
ATOM   9686  C  CD2 . LEU D 1 247 ? 163.168 126.335 122.698 1.00 49.56  ? 194 LEU A CD2 1 
ATOM   9687  N  N   . GLY D 1 248 ? 162.712 125.723 117.346 1.00 49.13  ? 195 GLY A N   1 
ATOM   9688  C  CA  . GLY D 1 248 ? 163.251 125.566 116.010 1.00 44.80  ? 195 GLY A CA  1 
ATOM   9689  C  C   . GLY D 1 248 ? 162.506 124.476 115.270 1.00 45.44  ? 195 GLY A C   1 
ATOM   9690  O  O   . GLY D 1 248 ? 161.426 124.058 115.683 1.00 45.81  ? 195 GLY A O   1 
ATOM   9691  N  N   . GLN D 1 249 ? 163.101 124.023 114.172 1.00 45.28  ? 196 GLN A N   1 
ATOM   9692  C  CA  . GLN D 1 249 ? 162.488 122.978 113.371 1.00 43.21  ? 196 GLN A CA  1 
ATOM   9693  C  C   . GLN D 1 249 ? 163.568 122.090 112.778 1.00 44.53  ? 196 GLN A C   1 
ATOM   9694  O  O   . GLN D 1 249 ? 164.703 122.520 112.567 1.00 50.79  ? 196 GLN A O   1 
ATOM   9695  C  CB  . GLN D 1 249 ? 161.619 123.557 112.253 1.00 39.50  ? 196 GLN A CB  1 
ATOM   9696  C  CG  . GLN D 1 249 ? 162.381 124.396 111.259 1.00 45.11  ? 196 GLN A CG  1 
ATOM   9697  C  CD  . GLN D 1 249 ? 162.309 125.868 111.572 1.00 52.58  ? 196 GLN A CD  1 
ATOM   9698  O  OE1 . GLN D 1 249 ? 161.506 126.299 112.394 1.00 53.40  ? 196 GLN A OE1 1 
ATOM   9699  N  NE2 . GLN D 1 249 ? 163.142 126.652 110.910 1.00 52.34  ? 196 GLN A NE2 1 
ATOM   9700  N  N   . THR D 1 250 ? 163.197 120.843 112.522 1.00 42.14  ? 197 THR A N   1 
ATOM   9701  C  CA  . THR D 1 250 ? 164.000 119.921 111.737 1.00 44.53  ? 197 THR A CA  1 
ATOM   9702  C  C   . THR D 1 250 ? 163.209 119.494 110.512 1.00 44.59  ? 197 THR A C   1 
ATOM   9703  O  O   . THR D 1 250 ? 161.977 119.476 110.525 1.00 45.31  ? 197 THR A O   1 
ATOM   9704  C  CB  . THR D 1 250 ? 164.423 118.685 112.539 1.00 47.51  ? 197 THR A CB  1 
ATOM   9705  O  OG1 . THR D 1 250 ? 163.272 117.917 112.896 1.00 50.13  ? 197 THR A OG1 1 
ATOM   9706  C  CG2 . THR D 1 250 ? 165.155 119.095 113.790 1.00 50.58  ? 197 THR A CG2 1 
ATOM   9707  N  N   . VAL D 1 251 ? 163.932 119.159 109.451 1.00 45.75  ? 198 VAL A N   1 
ATOM   9708  C  CA  . VAL D 1 251 ? 163.354 118.916 108.138 1.00 42.64  ? 198 VAL A CA  1 
ATOM   9709  C  C   . VAL D 1 251 ? 163.861 117.575 107.630 1.00 46.74  ? 198 VAL A C   1 
ATOM   9710  O  O   . VAL D 1 251 ? 165.057 117.284 107.727 1.00 51.13  ? 198 VAL A O   1 
ATOM   9711  C  CB  . VAL D 1 251 ? 163.710 120.049 107.159 1.00 43.05  ? 198 VAL A CB  1 
ATOM   9712  C  CG1 . VAL D 1 251 ? 163.585 119.581 105.754 1.00 46.09  ? 198 VAL A CG1 1 
ATOM   9713  C  CG2 . VAL D 1 251 ? 162.812 121.240 107.387 1.00 38.08  ? 198 VAL A CG2 1 
ATOM   9714  N  N   . ASP D 1 252 ? 162.956 116.758 107.094 1.00 48.22  ? 199 ASP A N   1 
ATOM   9715  C  CA  . ASP D 1 252 ? 163.317 115.423 106.650 1.00 49.62  ? 199 ASP A CA  1 
ATOM   9716  C  C   . ASP D 1 252 ? 162.422 115.020 105.488 1.00 50.84  ? 199 ASP A C   1 
ATOM   9717  O  O   . ASP D 1 252 ? 161.361 115.602 105.266 1.00 54.04  ? 199 ASP A O   1 
ATOM   9718  C  CB  . ASP D 1 252 ? 163.200 114.421 107.802 1.00 55.05  ? 199 ASP A CB  1 
ATOM   9719  C  CG  . ASP D 1 252 ? 163.819 113.085 107.478 1.00 70.99  ? 199 ASP A CG  1 
ATOM   9720  O  OD1 . ASP D 1 252 ? 164.451 112.963 106.409 1.00 69.83  ? 199 ASP A OD1 1 
ATOM   9721  O  OD2 . ASP D 1 252 ? 163.670 112.154 108.294 1.00 81.54  ? 199 ASP A OD2 1 
ATOM   9722  N  N   . SER D 1 253 ? 162.868 114.020 104.737 1.00 51.75  ? 200 SER A N   1 
ATOM   9723  C  CA  . SER D 1 253 ? 162.068 113.437 103.673 1.00 47.64  ? 200 SER A CA  1 
ATOM   9724  C  C   . SER D 1 253 ? 162.172 111.924 103.755 1.00 50.47  ? 200 SER A C   1 
ATOM   9725  O  O   . SER D 1 253 ? 163.203 111.381 104.153 1.00 56.94  ? 200 SER A O   1 
ATOM   9726  C  CB  . SER D 1 253 ? 162.511 113.928 102.293 1.00 43.73  ? 200 SER A CB  1 
ATOM   9727  O  OG  . SER D 1 253 ? 163.879 113.647 102.068 1.00 52.51  ? 200 SER A OG  1 
ATOM   9728  N  N   . GLY D 1 254 ? 161.096 111.246 103.378 1.00 45.51  ? 201 GLY A N   1 
ATOM   9729  C  CA  . GLY D 1 254 ? 161.074 109.807 103.473 1.00 44.15  ? 201 GLY A CA  1 
ATOM   9730  C  C   . GLY D 1 254 ? 160.009 109.207 102.587 1.00 43.18  ? 201 GLY A C   1 
ATOM   9731  O  O   . GLY D 1 254 ? 159.412 109.885 101.751 1.00 46.00  ? 201 GLY A O   1 
ATOM   9732  N  N   . ILE D 1 255 ? 159.774 107.915 102.786 1.00 43.09  ? 202 ILE A N   1 
ATOM   9733  C  CA  . ILE D 1 255 ? 158.829 107.145 101.989 1.00 43.61  ? 202 ILE A CA  1 
ATOM   9734  C  C   . ILE D 1 255 ? 157.768 106.573 102.914 1.00 46.08  ? 202 ILE A C   1 
ATOM   9735  O  O   . ILE D 1 255 ? 158.095 105.951 103.929 1.00 54.80  ? 202 ILE A O   1 
ATOM   9736  C  CB  . ILE D 1 255 ? 159.534 106.020 101.213 1.00 45.88  ? 202 ILE A CB  1 
ATOM   9737  C  CG1 . ILE D 1 255 ? 160.494 106.605 100.183 1.00 46.47  ? 202 ILE A CG1 1 
ATOM   9738  C  CG2 . ILE D 1 255 ? 158.526 105.114 100.539 1.00 46.38  ? 202 ILE A CG2 1 
ATOM   9739  C  CD1 . ILE D 1 255 ? 159.810 107.195 98.986  1.00 48.90  ? 202 ILE A CD1 1 
ATOM   9740  N  N   . VAL D 1 256 ? 156.506 106.783 102.567 1.00 43.42  ? 203 VAL A N   1 
ATOM   9741  C  CA  . VAL D 1 256 ? 155.396 106.145 103.251 1.00 47.81  ? 203 VAL A CA  1 
ATOM   9742  C  C   . VAL D 1 256 ? 154.806 105.109 102.308 1.00 52.29  ? 203 VAL A C   1 
ATOM   9743  O  O   . VAL D 1 256 ? 155.021 105.140 101.095 1.00 56.44  ? 203 VAL A O   1 
ATOM   9744  C  CB  . VAL D 1 256 ? 154.324 107.157 103.705 1.00 47.75  ? 203 VAL A CB  1 
ATOM   9745  C  CG1 . VAL D 1 256 ? 153.355 107.453 102.581 1.00 44.72  ? 203 VAL A CG1 1 
ATOM   9746  C  CG2 . VAL D 1 256 ? 153.587 106.639 104.914 1.00 49.25  ? 203 VAL A CG2 1 
ATOM   9747  N  N   . GLN D 1 257 ? 154.068 104.165 102.877 1.00 53.45  ? 204 GLN A N   1 
ATOM   9748  C  CA  . GLN D 1 257 ? 153.459 103.109 102.086 1.00 54.70  ? 204 GLN A CA  1 
ATOM   9749  C  C   . GLN D 1 257 ? 152.020 102.913 102.527 1.00 58.56  ? 204 GLN A C   1 
ATOM   9750  O  O   . GLN D 1 257 ? 151.743 102.831 103.726 1.00 66.70  ? 204 GLN A O   1 
ATOM   9751  C  CB  . GLN D 1 257 ? 154.243 101.803 102.225 1.00 56.30  ? 204 GLN A CB  1 
ATOM   9752  C  CG  . GLN D 1 257 ? 153.569 100.613 101.595 1.00 61.45  ? 204 GLN A CG  1 
ATOM   9753  C  CD  . GLN D 1 257 ? 154.441 99.389  101.622 1.00 83.14  ? 204 GLN A CD  1 
ATOM   9754  O  OE1 . GLN D 1 257 ? 155.667 99.490  101.650 1.00 87.51  ? 204 GLN A OE1 1 
ATOM   9755  N  NE2 . GLN D 1 257 ? 153.819 98.217  101.619 1.00 92.23  ? 204 GLN A NE2 1 
ATOM   9756  N  N   . SER D 1 258 ? 151.111 102.839 101.561 1.00 53.43  ? 205 SER A N   1 
ATOM   9757  C  CA  . SER D 1 258 ? 149.708 102.569 101.814 1.00 52.87  ? 205 SER A CA  1 
ATOM   9758  C  C   . SER D 1 258 ? 149.225 101.529 100.813 1.00 55.93  ? 205 SER A C   1 
ATOM   9759  O  O   . SER D 1 258 ? 149.980 101.065 99.954  1.00 59.62  ? 205 SER A O   1 
ATOM   9760  C  CB  . SER D 1 258 ? 148.868 103.847 101.732 1.00 55.39  ? 205 SER A CB  1 
ATOM   9761  O  OG  . SER D 1 258 ? 148.907 104.401 100.432 1.00 59.13  ? 205 SER A OG  1 
ATOM   9762  N  N   . SER D 1 259 ? 147.945 101.170 100.924 1.00 55.55  ? 206 SER A N   1 
ATOM   9763  C  CA  . SER D 1 259 ? 147.389 100.128 100.070 1.00 58.29  ? 206 SER A CA  1 
ATOM   9764  C  C   . SER D 1 259 ? 147.474 100.483 98.595  1.00 56.86  ? 206 SER A C   1 
ATOM   9765  O  O   . SER D 1 259 ? 147.486 99.583  97.750  1.00 58.45  ? 206 SER A O   1 
ATOM   9766  C  CB  . SER D 1 259 ? 145.936 99.859  100.454 1.00 59.25  ? 206 SER A CB  1 
ATOM   9767  O  OG  . SER D 1 259 ? 145.179 101.054 100.429 1.00 63.96  ? 206 SER A OG  1 
ATOM   9768  N  N   . THR D 1 260 ? 147.551 101.765 98.268  1.00 54.23  ? 207 THR A N   1 
ATOM   9769  C  CA  . THR D 1 260 ? 147.620 102.201 96.884  1.00 54.22  ? 207 THR A CA  1 
ATOM   9770  C  C   . THR D 1 260 ? 149.047 102.382 96.381  1.00 57.24  ? 207 THR A C   1 
ATOM   9771  O  O   . THR D 1 260 ? 149.228 102.765 95.223  1.00 63.59  ? 207 THR A O   1 
ATOM   9772  C  CB  . THR D 1 260 ? 146.830 103.500 96.708  1.00 51.53  ? 207 THR A CB  1 
ATOM   9773  O  OG1 . THR D 1 260 ? 147.246 104.454 97.690  1.00 55.62  ? 207 THR A OG1 1 
ATOM   9774  C  CG2 . THR D 1 260 ? 145.354 103.237 96.875  1.00 47.78  ? 207 THR A CG2 1 
ATOM   9775  N  N   . GLY D 1 261 ? 150.063 102.119 97.205  1.00 52.32  ? 208 GLY A N   1 
ATOM   9776  C  CA  . GLY D 1 261 ? 151.429 102.136 96.729  1.00 48.81  ? 208 GLY A CA  1 
ATOM   9777  C  C   . GLY D 1 261 ? 152.353 102.871 97.671  1.00 52.99  ? 208 GLY A C   1 
ATOM   9778  O  O   . GLY D 1 261 ? 152.014 103.157 98.823  1.00 58.02  ? 208 GLY A O   1 
ATOM   9779  N  N   . GLU D 1 262 ? 153.549 103.181 97.174  1.00 52.51  ? 209 GLU A N   1 
ATOM   9780  C  CA  . GLU D 1 262 ? 154.583 103.866 97.939  1.00 49.31  ? 209 GLU A CA  1 
ATOM   9781  C  C   . GLU D 1 262 ? 154.679 105.313 97.485  1.00 47.03  ? 209 GLU A C   1 
ATOM   9782  O  O   . GLU D 1 262 ? 154.788 105.583 96.287  1.00 49.12  ? 209 GLU A O   1 
ATOM   9783  C  CB  . GLU D 1 262 ? 155.939 103.182 97.770  1.00 53.93  ? 209 GLU A CB  1 
ATOM   9784  C  CG  . GLU D 1 262 ? 155.982 101.748 98.241  1.00 69.14  ? 209 GLU A CG  1 
ATOM   9785  C  CD  . GLU D 1 262 ? 157.393 101.196 98.284  1.00 89.18  ? 209 GLU A CD  1 
ATOM   9786  O  OE1 . GLU D 1 262 ? 158.314 101.883 97.794  1.00 88.46  ? 209 GLU A OE1 1 
ATOM   9787  O  OE2 . GLU D 1 262 ? 157.581 100.078 98.811  1.00 92.02  ? 209 GLU A OE2 1 
ATOM   9788  N  N   . TYR D 1 263 ? 154.669 106.233 98.442  1.00 45.29  ? 210 TYR A N   1 
ATOM   9789  C  CA  . TYR D 1 263 ? 154.642 107.659 98.166  1.00 42.78  ? 210 TYR A CA  1 
ATOM   9790  C  C   . TYR D 1 263 ? 155.794 108.340 98.884  1.00 42.47  ? 210 TYR A C   1 
ATOM   9791  O  O   . TYR D 1 263 ? 156.300 107.848 99.892  1.00 48.04  ? 210 TYR A O   1 
ATOM   9792  C  CB  . TYR D 1 263 ? 153.316 108.287 98.612  1.00 44.89  ? 210 TYR A CB  1 
ATOM   9793  C  CG  . TYR D 1 263 ? 152.096 107.707 97.945  1.00 44.51  ? 210 TYR A CG  1 
ATOM   9794  C  CD1 . TYR D 1 263 ? 151.487 106.568 98.437  1.00 43.52  ? 210 TYR A CD1 1 
ATOM   9795  C  CD2 . TYR D 1 263 ? 151.549 108.304 96.825  1.00 41.63  ? 210 TYR A CD2 1 
ATOM   9796  C  CE1 . TYR D 1 263 ? 150.379 106.041 97.830  1.00 44.35  ? 210 TYR A CE1 1 
ATOM   9797  C  CE2 . TYR D 1 263 ? 150.443 107.786 96.217  1.00 40.28  ? 210 TYR A CE2 1 
ATOM   9798  C  CZ  . TYR D 1 263 ? 149.862 106.654 96.718  1.00 45.87  ? 210 TYR A CZ  1 
ATOM   9799  O  OH  . TYR D 1 263 ? 148.752 106.138 96.101  1.00 50.47  ? 210 TYR A OH  1 
ATOM   9800  N  N   . VAL D 1 264 ? 156.207 109.476 98.353  1.00 40.49  ? 211 VAL A N   1 
ATOM   9801  C  CA  . VAL D 1 264 ? 157.195 110.331 98.998  1.00 38.59  ? 211 VAL A CA  1 
ATOM   9802  C  C   . VAL D 1 264 ? 156.467 111.246 99.967  1.00 40.53  ? 211 VAL A C   1 
ATOM   9803  O  O   . VAL D 1 264 ? 155.357 111.706 99.683  1.00 45.48  ? 211 VAL A O   1 
ATOM   9804  C  CB  . VAL D 1 264 ? 157.990 111.136 97.955  1.00 39.28  ? 211 VAL A CB  1 
ATOM   9805  C  CG1 . VAL D 1 264 ? 159.000 112.028 98.635  1.00 37.56  ? 211 VAL A CG1 1 
ATOM   9806  C  CG2 . VAL D 1 264 ? 158.682 110.207 96.985  1.00 40.03  ? 211 VAL A CG2 1 
ATOM   9807  N  N   . VAL D 1 265 ? 157.068 111.487 101.129 1.00 38.75  ? 212 VAL A N   1 
ATOM   9808  C  CA  . VAL D 1 265 ? 156.491 112.354 102.147 1.00 38.62  ? 212 VAL A CA  1 
ATOM   9809  C  C   . VAL D 1 265 ? 157.577 113.282 102.673 1.00 42.59  ? 212 VAL A C   1 
ATOM   9810  O  O   . VAL D 1 265 ? 158.712 112.857 102.914 1.00 47.44  ? 212 VAL A O   1 
ATOM   9811  C  CB  . VAL D 1 265 ? 155.849 111.536 103.288 1.00 37.04  ? 212 VAL A CB  1 
ATOM   9812  C  CG1 . VAL D 1 265 ? 156.860 110.620 103.932 1.00 40.97  ? 212 VAL A CG1 1 
ATOM   9813  C  CG2 . VAL D 1 265 ? 155.224 112.449 104.318 1.00 39.24  ? 212 VAL A CG2 1 
ATOM   9814  N  N   . MET D 1 266 ? 157.240 114.558 102.817 1.00 39.15  ? 213 MET A N   1 
ATOM   9815  C  CA  . MET D 1 266 ? 158.152 115.560 103.344 1.00 33.44  ? 213 MET A CA  1 
ATOM   9816  C  C   . MET D 1 266 ? 157.649 115.998 104.709 1.00 36.11  ? 213 MET A C   1 
ATOM   9817  O  O   . MET D 1 266 ? 156.467 116.324 104.859 1.00 41.77  ? 213 MET A O   1 
ATOM   9818  C  CB  . MET D 1 266 ? 158.256 116.757 102.400 1.00 33.45  ? 213 MET A CB  1 
ATOM   9819  C  CG  . MET D 1 266 ? 158.307 116.397 100.932 1.00 35.25  ? 213 MET A CG  1 
ATOM   9820  S  SD  . MET D 1 266 ? 159.811 115.547 100.448 1.00 56.23  ? 213 MET A SD  1 
ATOM   9821  C  CE  . MET D 1 266 ? 160.951 116.915 100.441 1.00 40.90  ? 213 MET A CE  1 
ATOM   9822  N  N   . THR D 1 267 ? 158.541 116.005 105.697 1.00 38.03  ? 214 THR A N   1 
ATOM   9823  C  CA  . THR D 1 267 ? 158.169 116.178 107.090 1.00 40.31  ? 214 THR A CA  1 
ATOM   9824  C  C   . THR D 1 267 ? 158.948 117.326 107.711 1.00 42.26  ? 214 THR A C   1 
ATOM   9825  O  O   . THR D 1 267 ? 160.150 117.475 107.477 1.00 46.43  ? 214 THR A O   1 
ATOM   9826  C  CB  . THR D 1 267 ? 158.433 114.903 107.887 1.00 44.53  ? 214 THR A CB  1 
ATOM   9827  O  OG1 . THR D 1 267 ? 158.043 113.766 107.111 1.00 48.41  ? 214 THR A OG1 1 
ATOM   9828  C  CG2 . THR D 1 267 ? 157.632 114.912 109.170 1.00 46.85  ? 214 THR A CG2 1 
ATOM   9829  N  N   . THR D 1 268 ? 158.253 118.132 108.506 1.00 42.51  ? 215 THR A N   1 
ATOM   9830  C  CA  . THR D 1 268 ? 158.876 119.180 109.300 1.00 41.97  ? 215 THR A CA  1 
ATOM   9831  C  C   . THR D 1 268 ? 158.415 119.045 110.740 1.00 44.36  ? 215 THR A C   1 
ATOM   9832  O  O   . THR D 1 268 ? 157.214 119.034 111.004 1.00 49.27  ? 215 THR A O   1 
ATOM   9833  C  CB  . THR D 1 268 ? 158.518 120.570 108.782 1.00 39.96  ? 215 THR A CB  1 
ATOM   9834  O  OG1 . THR D 1 268 ? 158.512 120.561 107.352 1.00 48.22  ? 215 THR A OG1 1 
ATOM   9835  C  CG2 . THR D 1 268 ? 159.531 121.578 109.263 1.00 41.45  ? 215 THR A CG2 1 
ATOM   9836  N  N   . HIS D 1 269 ? 159.358 118.953 111.667 1.00 42.74  ? 216 HIS A N   1 
ATOM   9837  C  CA  . HIS D 1 269 ? 159.047 118.916 113.089 1.00 40.30  ? 216 HIS A CA  1 
ATOM   9838  C  C   . HIS D 1 269 ? 159.372 120.269 113.693 1.00 39.32  ? 216 HIS A C   1 
ATOM   9839  O  O   . HIS D 1 269 ? 160.526 120.700 113.658 1.00 46.68  ? 216 HIS A O   1 
ATOM   9840  C  CB  . HIS D 1 269 ? 159.832 117.820 113.804 1.00 43.07  ? 216 HIS A CB  1 
ATOM   9841  C  CG  . HIS D 1 269 ? 159.397 116.437 113.449 1.00 47.75  ? 216 HIS A CG  1 
ATOM   9842  N  ND1 . HIS D 1 269 ? 159.831 115.790 112.315 1.00 50.39  ? 216 HIS A ND1 1 
ATOM   9843  C  CD2 . HIS D 1 269 ? 158.560 115.579 114.075 1.00 51.28  ? 216 HIS A CD2 1 
ATOM   9844  C  CE1 . HIS D 1 269 ? 159.282 114.591 112.259 1.00 57.64  ? 216 HIS A CE1 1 
ATOM   9845  N  NE2 . HIS D 1 269 ? 158.505 114.439 113.314 1.00 58.70  ? 216 HIS A NE2 1 
ATOM   9846  N  N   . PHE D 1 270 ? 158.364 120.933 114.242 1.00 34.79  ? 217 PHE A N   1 
ATOM   9847  C  CA  . PHE D 1 270 ? 158.575 122.151 115.011 1.00 36.11  ? 217 PHE A CA  1 
ATOM   9848  C  C   . PHE D 1 270 ? 158.683 121.770 116.478 1.00 41.47  ? 217 PHE A C   1 
ATOM   9849  O  O   . PHE D 1 270 ? 157.780 121.130 117.020 1.00 45.51  ? 217 PHE A O   1 
ATOM   9850  C  CB  . PHE D 1 270 ? 157.431 123.140 114.809 1.00 37.67  ? 217 PHE A CB  1 
ATOM   9851  C  CG  . PHE D 1 270 ? 157.123 123.438 113.375 1.00 36.13  ? 217 PHE A CG  1 
ATOM   9852  C  CD1 . PHE D 1 270 ? 157.758 124.465 112.714 1.00 37.51  ? 217 PHE A CD1 1 
ATOM   9853  C  CD2 . PHE D 1 270 ? 156.182 122.702 112.694 1.00 35.31  ? 217 PHE A CD2 1 
ATOM   9854  C  CE1 . PHE D 1 270 ? 157.471 124.738 111.402 1.00 38.34  ? 217 PHE A CE1 1 
ATOM   9855  C  CE2 . PHE D 1 270 ? 155.893 122.973 111.383 1.00 33.58  ? 217 PHE A CE2 1 
ATOM   9856  C  CZ  . PHE D 1 270 ? 156.536 123.991 110.737 1.00 32.70  ? 217 PHE A CZ  1 
ATOM   9857  N  N   . HIS D 1 271 ? 159.771 122.171 117.123 1.00 44.02  ? 218 HIS A N   1 
ATOM   9858  C  CA  . HIS D 1 271 ? 160.022 121.819 118.512 1.00 43.17  ? 218 HIS A CA  1 
ATOM   9859  C  C   . HIS D 1 271 ? 159.558 122.950 119.416 1.00 42.17  ? 218 HIS A C   1 
ATOM   9860  O  O   . HIS D 1 271 ? 159.954 124.102 119.229 1.00 44.89  ? 218 HIS A O   1 
ATOM   9861  C  CB  . HIS D 1 271 ? 161.502 121.519 118.731 1.00 41.72  ? 218 HIS A CB  1 
ATOM   9862  C  CG  . HIS D 1 271 ? 162.025 120.436 117.844 1.00 45.62  ? 218 HIS A CG  1 
ATOM   9863  N  ND1 . HIS D 1 271 ? 161.893 119.100 118.148 1.00 49.45  ? 218 HIS A ND1 1 
ATOM   9864  C  CD2 . HIS D 1 271 ? 162.656 120.489 116.649 1.00 46.81  ? 218 HIS A CD2 1 
ATOM   9865  C  CE1 . HIS D 1 271 ? 162.430 118.377 117.183 1.00 54.44  ? 218 HIS A CE1 1 
ATOM   9866  N  NE2 . HIS D 1 271 ? 162.901 119.196 116.262 1.00 51.18  ? 218 HIS A NE2 1 
ATOM   9867  N  N   . LEU D 1 272 ? 158.712 122.616 120.384 1.00 42.84  ? 219 LEU A N   1 
ATOM   9868  C  CA  . LEU D 1 272 ? 158.122 123.574 121.303 1.00 42.84  ? 219 LEU A CA  1 
ATOM   9869  C  C   . LEU D 1 272 ? 158.444 123.176 122.731 1.00 47.66  ? 219 LEU A C   1 
ATOM   9870  O  O   . LEU D 1 272 ? 158.510 121.987 123.052 1.00 55.19  ? 219 LEU A O   1 
ATOM   9871  C  CB  . LEU D 1 272 ? 156.609 123.644 121.142 1.00 38.10  ? 219 LEU A CB  1 
ATOM   9872  C  CG  . LEU D 1 272 ? 156.023 123.827 119.753 1.00 38.00  ? 219 LEU A CG  1 
ATOM   9873  C  CD1 . LEU D 1 272 ? 154.558 123.513 119.819 1.00 41.14  ? 219 LEU A CD1 1 
ATOM   9874  C  CD2 . LEU D 1 272 ? 156.232 125.234 119.279 1.00 37.47  ? 219 LEU A CD2 1 
ATOM   9875  N  N   . LYS D 1 273 ? 158.644 124.175 123.582 1.00 44.94  ? 220 LYS A N   1 
ATOM   9876  C  CA  . LYS D 1 273 ? 158.806 123.981 125.013 1.00 43.66  ? 220 LYS A CA  1 
ATOM   9877  C  C   . LYS D 1 273 ? 157.823 124.882 125.740 1.00 45.41  ? 220 LYS A C   1 
ATOM   9878  O  O   . LYS D 1 273 ? 157.644 126.041 125.364 1.00 50.02  ? 220 LYS A O   1 
ATOM   9879  C  CB  . LYS D 1 273 ? 160.234 124.282 125.453 1.00 46.38  ? 220 LYS A CB  1 
ATOM   9880  C  CG  . LYS D 1 273 ? 160.510 123.980 126.909 1.00 52.99  ? 220 LYS A CG  1 
ATOM   9881  C  CD  . LYS D 1 273 ? 161.967 124.218 127.236 1.00 67.51  ? 220 LYS A CD  1 
ATOM   9882  C  CE  . LYS D 1 273 ? 162.254 123.992 128.709 1.00 79.95  ? 220 LYS A CE  1 
ATOM   9883  N  NZ  . LYS D 1 273 ? 163.670 124.304 129.033 1.00 83.83  ? 220 LYS A NZ  1 
ATOM   9884  N  N   . ARG D 1 274 ? 157.184 124.349 126.773 1.00 40.44  ? 221 ARG A N   1 
ATOM   9885  C  CA  . ARG D 1 274 ? 156.132 125.080 127.462 1.00 39.91  ? 221 ARG A CA  1 
ATOM   9886  C  C   . ARG D 1 274 ? 156.706 126.077 128.456 1.00 48.55  ? 221 ARG A C   1 
ATOM   9887  O  O   . ARG D 1 274 ? 157.664 125.782 129.172 1.00 50.96  ? 221 ARG A O   1 
ATOM   9888  C  CB  . ARG D 1 274 ? 155.197 124.116 128.186 1.00 35.98  ? 221 ARG A CB  1 
ATOM   9889  C  CG  . ARG D 1 274 ? 154.026 124.801 128.852 1.00 39.86  ? 221 ARG A CG  1 
ATOM   9890  C  CD  . ARG D 1 274 ? 153.251 123.847 129.713 1.00 43.77  ? 221 ARG A CD  1 
ATOM   9891  N  NE  . ARG D 1 274 ? 152.776 122.697 128.958 1.00 45.18  ? 221 ARG A NE  1 
ATOM   9892  C  CZ  . ARG D 1 274 ? 151.595 122.631 128.365 1.00 47.34  ? 221 ARG A CZ  1 
ATOM   9893  N  NH1 . ARG D 1 274 ? 150.746 123.643 128.406 1.00 44.85  ? 221 ARG A NH1 1 
ATOM   9894  N  NH2 . ARG D 1 274 ? 151.259 121.524 127.712 1.00 49.92  ? 221 ARG A NH2 1 
ATOM   9895  N  N   . LYS D 1 275 ? 156.112 127.266 128.493 1.00 48.65  ? 222 LYS A N   1 
ATOM   9896  C  CA  . LYS D 1 275 ? 156.468 128.259 129.493 1.00 42.09  ? 222 LYS A CA  1 
ATOM   9897  C  C   . LYS D 1 275 ? 155.977 127.822 130.865 1.00 45.02  ? 222 LYS A C   1 
ATOM   9898  O  O   . LYS D 1 275 ? 154.905 127.229 130.998 1.00 49.06  ? 222 LYS A O   1 
ATOM   9899  C  CB  . LYS D 1 275 ? 155.861 129.611 129.138 1.00 42.78  ? 222 LYS A CB  1 
ATOM   9900  C  CG  . LYS D 1 275 ? 156.280 130.176 127.801 1.00 45.39  ? 222 LYS A CG  1 
ATOM   9901  C  CD  . LYS D 1 275 ? 155.517 131.457 127.528 1.00 50.09  ? 222 LYS A CD  1 
ATOM   9902  C  CE  . LYS D 1 275 ? 156.051 132.173 126.314 1.00 51.85  ? 222 LYS A CE  1 
ATOM   9903  N  NZ  . LYS D 1 275 ? 157.499 132.453 126.470 1.00 55.04  ? 222 LYS A NZ  1 
ATOM   9904  N  N   . ILE D 1 276 ? 156.751 128.144 131.898 1.00 40.54  ? 223 ILE A N   1 
ATOM   9905  C  CA  . ILE D 1 276 ? 156.481 127.647 133.241 1.00 40.05  ? 223 ILE A CA  1 
ATOM   9906  C  C   . ILE D 1 276 ? 156.166 128.746 134.246 1.00 42.64  ? 223 ILE A C   1 
ATOM   9907  O  O   . ILE D 1 276 ? 155.700 128.430 135.348 1.00 47.20  ? 223 ILE A O   1 
ATOM   9908  C  CB  . ILE D 1 276 ? 157.650 126.782 133.758 1.00 38.04  ? 223 ILE A CB  1 
ATOM   9909  C  CG1 . ILE D 1 276 ? 157.160 125.776 134.796 1.00 44.89  ? 223 ILE A CG1 1 
ATOM   9910  C  CG2 . ILE D 1 276 ? 158.738 127.656 134.339 1.00 37.50  ? 223 ILE A CG2 1 
ATOM   9911  C  CD1 . ILE D 1 276 ? 158.267 125.139 135.577 1.00 49.94  ? 223 ILE A CD1 1 
ATOM   9912  N  N   . GLY D 1 277 ? 156.374 130.020 133.912 1.00 38.73  ? 224 GLY A N   1 
ATOM   9913  C  CA  . GLY D 1 277 ? 156.221 131.072 134.909 1.00 35.24  ? 224 GLY A CA  1 
ATOM   9914  C  C   . GLY D 1 277 ? 154.817 131.169 135.477 1.00 35.27  ? 224 GLY A C   1 
ATOM   9915  O  O   . GLY D 1 277 ? 154.635 131.432 136.669 1.00 38.77  ? 224 GLY A O   1 
ATOM   9916  N  N   . TYR D 1 278 ? 153.807 130.955 134.635 1.00 32.41  ? 225 TYR A N   1 
ATOM   9917  C  CA  . TYR D 1 278 ? 152.426 131.016 135.099 1.00 34.08  ? 225 TYR A CA  1 
ATOM   9918  C  C   . TYR D 1 278 ? 152.160 129.967 136.169 1.00 40.11  ? 225 TYR A C   1 
ATOM   9919  O  O   . TYR D 1 278 ? 151.517 130.250 137.186 1.00 45.91  ? 225 TYR A O   1 
ATOM   9920  C  CB  . TYR D 1 278 ? 151.482 130.831 133.913 1.00 35.51  ? 225 TYR A CB  1 
ATOM   9921  C  CG  . TYR D 1 278 ? 150.017 130.992 134.230 1.00 39.39  ? 225 TYR A CG  1 
ATOM   9922  C  CD1 . TYR D 1 278 ? 149.538 132.153 134.810 1.00 42.24  ? 225 TYR A CD1 1 
ATOM   9923  C  CD2 . TYR D 1 278 ? 149.108 129.993 133.920 1.00 38.44  ? 225 TYR A CD2 1 
ATOM   9924  C  CE1 . TYR D 1 278 ? 148.203 132.309 135.091 1.00 45.20  ? 225 TYR A CE1 1 
ATOM   9925  C  CE2 . TYR D 1 278 ? 147.770 130.141 134.195 1.00 42.50  ? 225 TYR A CE2 1 
ATOM   9926  C  CZ  . TYR D 1 278 ? 147.324 131.301 134.781 1.00 49.54  ? 225 TYR A CZ  1 
ATOM   9927  O  OH  . TYR D 1 278 ? 145.990 131.456 135.061 1.00 59.20  ? 225 TYR A OH  1 
ATOM   9928  N  N   . PHE D 1 279 ? 152.658 128.749 135.963 1.00 40.56  ? 226 PHE A N   1 
ATOM   9929  C  CA  . PHE D 1 279 ? 152.444 127.694 136.943 1.00 36.35  ? 226 PHE A CA  1 
ATOM   9930  C  C   . PHE D 1 279 ? 153.291 127.902 138.187 1.00 37.82  ? 226 PHE A C   1 
ATOM   9931  O  O   . PHE D 1 279 ? 152.899 127.477 139.276 1.00 39.82  ? 226 PHE A O   1 
ATOM   9932  C  CB  . PHE D 1 279 ? 152.734 126.341 136.311 1.00 37.26  ? 226 PHE A CB  1 
ATOM   9933  C  CG  . PHE D 1 279 ? 151.972 126.099 135.046 1.00 41.86  ? 226 PHE A CG  1 
ATOM   9934  C  CD1 . PHE D 1 279 ? 150.712 125.541 135.080 1.00 39.15  ? 226 PHE A CD1 1 
ATOM   9935  C  CD2 . PHE D 1 279 ? 152.512 126.438 133.824 1.00 42.22  ? 226 PHE A CD2 1 
ATOM   9936  C  CE1 . PHE D 1 279 ? 150.012 125.319 133.920 1.00 39.31  ? 226 PHE A CE1 1 
ATOM   9937  C  CE2 . PHE D 1 279 ? 151.815 126.219 132.664 1.00 42.15  ? 226 PHE A CE2 1 
ATOM   9938  C  CZ  . PHE D 1 279 ? 150.563 125.659 132.712 1.00 43.74  ? 226 PHE A CZ  1 
ATOM   9939  N  N   . VAL D 1 280 ? 154.449 128.547 138.051 1.00 38.73  ? 227 VAL A N   1 
ATOM   9940  C  CA  . VAL D 1 280 ? 155.242 128.889 139.224 1.00 37.55  ? 227 VAL A CA  1 
ATOM   9941  C  C   . VAL D 1 280 ? 154.497 129.889 140.092 1.00 38.68  ? 227 VAL A C   1 
ATOM   9942  O  O   . VAL D 1 280 ? 154.488 129.778 141.322 1.00 41.75  ? 227 VAL A O   1 
ATOM   9943  C  CB  . VAL D 1 280 ? 156.625 129.421 138.808 1.00 37.79  ? 227 VAL A CB  1 
ATOM   9944  C  CG1 . VAL D 1 280 ? 157.364 129.969 140.010 1.00 40.35  ? 227 VAL A CG1 1 
ATOM   9945  C  CG2 . VAL D 1 280 ? 157.432 128.328 138.159 1.00 39.96  ? 227 VAL A CG2 1 
ATOM   9946  N  N   . ILE D 1 281 ? 153.855 130.880 139.473 1.00 39.23  ? 228 ILE A N   1 
ATOM   9947  C  CA  . ILE D 1 281 ? 153.173 131.889 140.275 1.00 38.52  ? 228 ILE A CA  1 
ATOM   9948  C  C   . ILE D 1 281 ? 151.799 131.437 140.749 1.00 40.72  ? 228 ILE A C   1 
ATOM   9949  O  O   . ILE D 1 281 ? 151.291 131.979 141.735 1.00 45.33  ? 228 ILE A O   1 
ATOM   9950  C  CB  . ILE D 1 281 ? 153.040 133.223 139.524 1.00 34.53  ? 228 ILE A CB  1 
ATOM   9951  C  CG1 . ILE D 1 281 ? 152.940 134.371 140.521 1.00 37.15  ? 228 ILE A CG1 1 
ATOM   9952  C  CG2 . ILE D 1 281 ? 151.816 133.229 138.641 1.00 37.36  ? 228 ILE A CG2 1 
ATOM   9953  C  CD1 . ILE D 1 281 ? 152.595 135.689 139.903 1.00 47.72  ? 228 ILE A CD1 1 
ATOM   9954  N  N   . GLN D 1 282 ? 151.176 130.461 140.095 1.00 40.97  ? 229 GLN A N   1 
ATOM   9955  C  CA  . GLN D 1 282 ? 149.826 130.071 140.481 1.00 41.62  ? 229 GLN A CA  1 
ATOM   9956  C  C   . GLN D 1 282 ? 149.771 128.834 141.364 1.00 42.45  ? 229 GLN A C   1 
ATOM   9957  O  O   . GLN D 1 282 ? 148.870 128.733 142.199 1.00 46.16  ? 229 GLN A O   1 
ATOM   9958  C  CB  . GLN D 1 282 ? 148.962 129.837 139.239 1.00 41.60  ? 229 GLN A CB  1 
ATOM   9959  C  CG  . GLN D 1 282 ? 148.709 131.083 138.413 1.00 44.30  ? 229 GLN A CG  1 
ATOM   9960  C  CD  . GLN D 1 282 ? 147.719 132.029 139.055 1.00 49.48  ? 229 GLN A CD  1 
ATOM   9961  O  OE1 . GLN D 1 282 ? 146.512 131.907 138.860 1.00 56.36  ? 229 GLN A OE1 1 
ATOM   9962  N  NE2 . GLN D 1 282 ? 148.224 132.980 139.824 1.00 50.54  ? 229 GLN A NE2 1 
ATOM   9963  N  N   . THR D 1 283 ? 150.687 127.884 141.202 1.00 43.64  ? 230 THR A N   1 
ATOM   9964  C  CA  . THR D 1 283 ? 150.631 126.646 141.968 1.00 41.48  ? 230 THR A CA  1 
ATOM   9965  C  C   . THR D 1 283 ? 151.853 126.412 142.840 1.00 44.23  ? 230 THR A C   1 
ATOM   9966  O  O   . THR D 1 283 ? 151.706 126.148 144.036 1.00 48.74  ? 230 THR A O   1 
ATOM   9967  C  CB  . THR D 1 283 ? 150.445 125.453 141.026 1.00 43.26  ? 230 THR A CB  1 
ATOM   9968  O  OG1 . THR D 1 283 ? 149.174 125.551 140.376 1.00 46.57  ? 230 THR A OG1 1 
ATOM   9969  C  CG2 . THR D 1 283 ? 150.504 124.161 141.803 1.00 45.04  ? 230 THR A CG2 1 
ATOM   9970  N  N   . TYR D 1 284 ? 153.058 126.493 142.278 1.00 41.40  ? 231 TYR A N   1 
ATOM   9971  C  CA  . TYR D 1 284 ? 154.241 126.000 142.977 1.00 40.43  ? 231 TYR A CA  1 
ATOM   9972  C  C   . TYR D 1 284 ? 154.585 126.855 144.190 1.00 42.58  ? 231 TYR A C   1 
ATOM   9973  O  O   . TYR D 1 284 ? 154.855 126.327 145.274 1.00 47.32  ? 231 TYR A O   1 
ATOM   9974  C  CB  . TYR D 1 284 ? 155.416 125.926 142.011 1.00 43.89  ? 231 TYR A CB  1 
ATOM   9975  C  CG  . TYR D 1 284 ? 155.345 124.740 141.087 1.00 49.23  ? 231 TYR A CG  1 
ATOM   9976  C  CD1 . TYR D 1 284 ? 155.567 123.461 141.563 1.00 50.36  ? 231 TYR A CD1 1 
ATOM   9977  C  CD2 . TYR D 1 284 ? 155.060 124.896 139.741 1.00 50.90  ? 231 TYR A CD2 1 
ATOM   9978  C  CE1 . TYR D 1 284 ? 155.504 122.374 140.732 1.00 51.17  ? 231 TYR A CE1 1 
ATOM   9979  C  CE2 . TYR D 1 284 ? 154.997 123.810 138.899 1.00 51.58  ? 231 TYR A CE2 1 
ATOM   9980  C  CZ  . TYR D 1 284 ? 155.220 122.552 139.403 1.00 50.99  ? 231 TYR A CZ  1 
ATOM   9981  O  OH  . TYR D 1 284 ? 155.162 121.460 138.580 1.00 53.24  ? 231 TYR A OH  1 
ATOM   9982  N  N   . LEU D 1 285 ? 154.605 128.172 144.029 1.00 41.44  ? 232 LEU A N   1 
ATOM   9983  C  CA  . LEU D 1 285 ? 154.867 129.037 145.178 1.00 42.25  ? 232 LEU A CA  1 
ATOM   9984  C  C   . LEU D 1 285 ? 153.787 128.952 146.250 1.00 44.98  ? 232 LEU A C   1 
ATOM   9985  O  O   . LEU D 1 285 ? 154.143 128.870 147.438 1.00 47.95  ? 232 LEU A O   1 
ATOM   9986  C  CB  . LEU D 1 285 ? 155.085 130.477 144.710 1.00 40.18  ? 232 LEU A CB  1 
ATOM   9987  C  CG  . LEU D 1 285 ? 156.466 130.745 144.123 1.00 49.91  ? 232 LEU A CG  1 
ATOM   9988  C  CD1 . LEU D 1 285 ? 156.657 132.214 143.861 1.00 51.32  ? 232 LEU A CD1 1 
ATOM   9989  C  CD2 . LEU D 1 285 ? 157.543 130.230 145.053 1.00 51.04  ? 232 LEU A CD2 1 
ATOM   9990  N  N   . PRO D 1 286 ? 152.485 129.005 145.937 1.00 43.56  ? 233 PRO A N   1 
ATOM   9991  C  CA  . PRO D 1 286 ? 151.494 128.831 147.009 1.00 41.19  ? 233 PRO A CA  1 
ATOM   9992  C  C   . PRO D 1 286 ? 151.618 127.507 147.740 1.00 43.56  ? 233 PRO A C   1 
ATOM   9993  O  O   . PRO D 1 286 ? 151.464 127.468 148.965 1.00 47.93  ? 233 PRO A O   1 
ATOM   9994  C  CB  . PRO D 1 286 ? 150.161 128.952 146.263 1.00 38.00  ? 233 PRO A CB  1 
ATOM   9995  C  CG  . PRO D 1 286 ? 150.468 129.793 145.109 1.00 39.54  ? 233 PRO A CG  1 
ATOM   9996  C  CD  . PRO D 1 286 ? 151.835 129.392 144.674 1.00 40.47  ? 233 PRO A CD  1 
ATOM   9997  N  N   . CYS D 1 287 ? 151.916 126.419 147.026 1.00 39.01  ? 234 CYS A N   1 
ATOM   9998  C  CA  . CYS D 1 287 ? 152.069 125.125 147.682 1.00 40.40  ? 234 CYS A CA  1 
ATOM   9999  C  C   . CYS D 1 287 ? 153.302 125.092 148.573 1.00 45.23  ? 234 CYS A C   1 
ATOM   10000 O  O   . CYS D 1 287 ? 153.257 124.548 149.684 1.00 52.92  ? 234 CYS A O   1 
ATOM   10001 C  CB  . CYS D 1 287 ? 152.133 124.013 146.640 1.00 43.32  ? 234 CYS A CB  1 
ATOM   10002 S  SG  . CYS D 1 287 ? 150.549 123.602 145.898 1.00 64.95  ? 234 CYS A SG  1 
ATOM   10003 N  N   . ILE D 1 288 ? 154.416 125.653 148.104 1.00 41.50  ? 235 ILE A N   1 
ATOM   10004 C  CA  . ILE D 1 288 ? 155.618 125.684 148.931 1.00 43.80  ? 235 ILE A CA  1 
ATOM   10005 C  C   . ILE D 1 288 ? 155.377 126.513 150.182 1.00 48.91  ? 235 ILE A C   1 
ATOM   10006 O  O   . ILE D 1 288 ? 155.770 126.125 151.291 1.00 54.01  ? 235 ILE A O   1 
ATOM   10007 C  CB  . ILE D 1 288 ? 156.815 126.205 148.119 1.00 43.03  ? 235 ILE A CB  1 
ATOM   10008 C  CG1 . ILE D 1 288 ? 157.241 125.159 147.090 1.00 44.98  ? 235 ILE A CG1 1 
ATOM   10009 C  CG2 . ILE D 1 288 ? 157.965 126.532 149.031 1.00 36.51  ? 235 ILE A CG2 1 
ATOM   10010 C  CD1 . ILE D 1 288 ? 158.393 125.584 146.224 1.00 42.74  ? 235 ILE A CD1 1 
ATOM   10011 N  N   . MET D 1 289 ? 154.711 127.659 150.029 1.00 48.74  ? 236 MET A N   1 
ATOM   10012 C  CA  . MET D 1 289 ? 154.394 128.490 151.185 1.00 46.27  ? 236 MET A CA  1 
ATOM   10013 C  C   . MET D 1 289 ? 153.483 127.759 152.157 1.00 46.13  ? 236 MET A C   1 
ATOM   10014 O  O   . MET D 1 289 ? 153.662 127.857 153.373 1.00 55.56  ? 236 MET A O   1 
ATOM   10015 C  CB  . MET D 1 289 ? 153.746 129.795 150.733 1.00 44.97  ? 236 MET A CB  1 
ATOM   10016 C  CG  . MET D 1 289 ? 154.660 130.707 149.951 1.00 48.08  ? 236 MET A CG  1 
ATOM   10017 S  SD  . MET D 1 289 ? 153.762 132.090 149.236 1.00 73.80  ? 236 MET A SD  1 
ATOM   10018 C  CE  . MET D 1 289 ? 153.322 132.985 150.715 1.00 68.90  ? 236 MET A CE  1 
ATOM   10019 N  N   . THR D 1 290 ? 152.492 127.030 151.644 1.00 42.85  ? 237 THR A N   1 
ATOM   10020 C  CA  . THR D 1 290 ? 151.593 126.285 152.518 1.00 44.86  ? 237 THR A CA  1 
ATOM   10021 C  C   . THR D 1 290 ? 152.342 125.216 153.301 1.00 45.91  ? 237 THR A C   1 
ATOM   10022 O  O   . THR D 1 290 ? 152.122 125.049 154.507 1.00 51.05  ? 237 THR A O   1 
ATOM   10023 C  CB  . THR D 1 290 ? 150.470 125.658 151.699 1.00 44.83  ? 237 THR A CB  1 
ATOM   10024 O  OG1 . THR D 1 290 ? 149.681 126.692 151.107 1.00 46.84  ? 237 THR A OG1 1 
ATOM   10025 C  CG2 . THR D 1 290 ? 149.587 124.807 152.575 1.00 44.80  ? 237 THR A CG2 1 
ATOM   10026 N  N   . VAL D 1 291 ? 153.237 124.484 152.638 1.00 45.22  ? 238 VAL A N   1 
ATOM   10027 C  CA  . VAL D 1 291 ? 153.991 123.450 153.340 1.00 45.30  ? 238 VAL A CA  1 
ATOM   10028 C  C   . VAL D 1 291 ? 154.879 124.071 154.411 1.00 48.81  ? 238 VAL A C   1 
ATOM   10029 O  O   . VAL D 1 291 ? 154.981 123.552 155.530 1.00 56.73  ? 238 VAL A O   1 
ATOM   10030 C  CB  . VAL D 1 291 ? 154.799 122.602 152.343 1.00 47.94  ? 238 VAL A CB  1 
ATOM   10031 C  CG1 . VAL D 1 291 ? 155.681 121.630 153.081 1.00 50.53  ? 238 VAL A CG1 1 
ATOM   10032 C  CG2 . VAL D 1 291 ? 153.862 121.849 151.428 1.00 49.22  ? 238 VAL A CG2 1 
ATOM   10033 N  N   . ILE D 1 292 ? 155.521 125.198 154.098 1.00 47.09  ? 239 ILE A N   1 
ATOM   10034 C  CA  . ILE D 1 292 ? 156.359 125.869 155.091 1.00 50.90  ? 239 ILE A CA  1 
ATOM   10035 C  C   . ILE D 1 292 ? 155.521 126.347 156.272 1.00 55.21  ? 239 ILE A C   1 
ATOM   10036 O  O   . ILE D 1 292 ? 155.936 126.243 157.434 1.00 60.38  ? 239 ILE A O   1 
ATOM   10037 C  CB  . ILE D 1 292 ? 157.129 127.027 154.436 1.00 49.15  ? 239 ILE A CB  1 
ATOM   10038 C  CG1 . ILE D 1 292 ? 158.159 126.479 153.453 1.00 47.98  ? 239 ILE A CG1 1 
ATOM   10039 C  CG2 . ILE D 1 292 ? 157.807 127.882 155.488 1.00 49.41  ? 239 ILE A CG2 1 
ATOM   10040 C  CD1 . ILE D 1 292 ? 158.801 127.538 152.603 1.00 44.37  ? 239 ILE A CD1 1 
ATOM   10041 N  N   . LEU D 1 293 ? 154.336 126.886 155.993 1.00 55.34  ? 240 LEU A N   1 
ATOM   10042 C  CA  . LEU D 1 293 ? 153.459 127.359 157.057 1.00 53.60  ? 240 LEU A CA  1 
ATOM   10043 C  C   . LEU D 1 293 ? 153.016 126.213 157.953 1.00 57.59  ? 240 LEU A C   1 
ATOM   10044 O  O   . LEU D 1 293 ? 152.866 126.386 159.166 1.00 64.41  ? 240 LEU A O   1 
ATOM   10045 C  CB  . LEU D 1 293 ? 152.249 128.060 156.449 1.00 50.43  ? 240 LEU A CB  1 
ATOM   10046 C  CG  . LEU D 1 293 ? 151.259 128.727 157.395 1.00 55.28  ? 240 LEU A CG  1 
ATOM   10047 C  CD1 . LEU D 1 293 ? 151.895 129.929 158.065 1.00 58.91  ? 240 LEU A CD1 1 
ATOM   10048 C  CD2 . LEU D 1 293 ? 150.021 129.127 156.624 1.00 56.01  ? 240 LEU A CD2 1 
ATOM   10049 N  N   . SER D 1 294 ? 152.772 125.040 157.369 1.00 54.96  ? 241 SER A N   1 
ATOM   10050 C  CA  . SER D 1 294 ? 152.450 123.878 158.189 1.00 53.06  ? 241 SER A CA  1 
ATOM   10051 C  C   . SER D 1 294 ? 153.638 123.457 159.038 1.00 59.40  ? 241 SER A C   1 
ATOM   10052 O  O   . SER D 1 294 ? 153.479 123.111 160.213 1.00 64.17  ? 241 SER A O   1 
ATOM   10053 C  CB  . SER D 1 294 ? 151.998 122.719 157.310 1.00 49.21  ? 241 SER A CB  1 
ATOM   10054 O  OG  . SER D 1 294 ? 153.069 122.237 156.525 1.00 54.95  ? 241 SER A OG  1 
ATOM   10055 N  N   . GLN D 1 295 ? 154.837 123.483 158.465 1.00 61.92  ? 242 GLN A N   1 
ATOM   10056 C  CA  . GLN D 1 295 ? 155.998 122.983 159.184 1.00 63.32  ? 242 GLN A CA  1 
ATOM   10057 C  C   . GLN D 1 295 ? 156.512 123.954 160.236 1.00 68.87  ? 242 GLN A C   1 
ATOM   10058 O  O   . GLN D 1 295 ? 157.307 123.548 161.089 1.00 74.94  ? 242 GLN A O   1 
ATOM   10059 C  CB  . GLN D 1 295 ? 157.115 122.637 158.204 1.00 63.61  ? 242 GLN A CB  1 
ATOM   10060 C  CG  . GLN D 1 295 ? 156.807 121.415 157.368 1.00 66.39  ? 242 GLN A CG  1 
ATOM   10061 C  CD  . GLN D 1 295 ? 157.928 121.056 156.429 1.00 71.36  ? 242 GLN A CD  1 
ATOM   10062 O  OE1 . GLN D 1 295 ? 157.863 120.053 155.723 1.00 71.61  ? 242 GLN A OE1 1 
ATOM   10063 N  NE2 . GLN D 1 295 ? 158.968 121.877 156.412 1.00 72.66  ? 242 GLN A NE2 1 
ATOM   10064 N  N   . VAL D 1 296 ? 156.094 125.217 160.201 1.00 70.68  ? 243 VAL A N   1 
ATOM   10065 C  CA  . VAL D 1 296 ? 156.508 126.144 161.251 1.00 74.82  ? 243 VAL A CA  1 
ATOM   10066 C  C   . VAL D 1 296 ? 155.572 126.047 162.449 1.00 72.86  ? 243 VAL A C   1 
ATOM   10067 O  O   . VAL D 1 296 ? 155.667 126.846 163.384 1.00 79.36  ? 243 VAL A O   1 
ATOM   10068 C  CB  . VAL D 1 296 ? 156.588 127.597 160.749 1.00 71.69  ? 243 VAL A CB  1 
ATOM   10069 C  CG1 . VAL D 1 296 ? 157.650 127.729 159.666 1.00 72.54  ? 243 VAL A CG1 1 
ATOM   10070 C  CG2 . VAL D 1 296 ? 155.242 128.073 160.264 1.00 63.46  ? 243 VAL A CG2 1 
ATOM   10071 N  N   . SER D 1 297 ? 154.658 125.077 162.431 1.00 68.36  ? 244 SER A N   1 
ATOM   10072 C  CA  . SER D 1 297 ? 153.820 124.826 163.596 1.00 70.43  ? 244 SER A CA  1 
ATOM   10073 C  C   . SER D 1 297 ? 154.551 124.072 164.695 1.00 76.49  ? 244 SER A C   1 
ATOM   10074 O  O   . SER D 1 297 ? 154.118 124.117 165.849 1.00 83.69  ? 244 SER A O   1 
ATOM   10075 C  CB  . SER D 1 297 ? 152.574 124.035 163.202 1.00 72.13  ? 244 SER A CB  1 
ATOM   10076 O  OG  . SER D 1 297 ? 151.803 124.738 162.249 1.00 80.01  ? 244 SER A OG  1 
ATOM   10077 N  N   . PHE D 1 298 ? 155.639 123.375 164.367 1.00 78.87  ? 245 PHE A N   1 
ATOM   10078 C  CA  . PHE D 1 298 ? 156.366 122.616 165.376 1.00 82.68  ? 245 PHE A CA  1 
ATOM   10079 C  C   . PHE D 1 298 ? 157.043 123.517 166.395 1.00 86.25  ? 245 PHE A C   1 
ATOM   10080 O  O   . PHE D 1 298 ? 157.471 123.032 167.446 1.00 88.42  ? 245 PHE A O   1 
ATOM   10081 C  CB  . PHE D 1 298 ? 157.409 121.718 164.713 1.00 83.77  ? 245 PHE A CB  1 
ATOM   10082 C  CG  . PHE D 1 298 ? 156.840 120.772 163.701 1.00 84.19  ? 245 PHE A CG  1 
ATOM   10083 C  CD1 . PHE D 1 298 ? 155.597 120.205 163.885 1.00 86.02  ? 245 PHE A CD1 1 
ATOM   10084 C  CD2 . PHE D 1 298 ? 157.549 120.456 162.560 1.00 82.34  ? 245 PHE A CD2 1 
ATOM   10085 C  CE1 . PHE D 1 298 ? 155.076 119.337 162.952 1.00 87.25  ? 245 PHE A CE1 1 
ATOM   10086 C  CE2 . PHE D 1 298 ? 157.031 119.590 161.627 1.00 84.13  ? 245 PHE A CE2 1 
ATOM   10087 C  CZ  . PHE D 1 298 ? 155.793 119.031 161.823 1.00 84.66  ? 245 PHE A CZ  1 
ATOM   10088 N  N   . TRP D 1 299 ? 157.169 124.807 166.099 1.00 86.25  ? 246 TRP A N   1 
ATOM   10089 C  CA  . TRP D 1 299 ? 157.755 125.760 167.026 1.00 89.58  ? 246 TRP A CA  1 
ATOM   10090 C  C   . TRP D 1 299 ? 156.730 126.415 167.938 1.00 93.07  ? 246 TRP A C   1 
ATOM   10091 O  O   . TRP D 1 299 ? 157.120 127.117 168.875 1.00 98.29  ? 246 TRP A O   1 
ATOM   10092 C  CB  . TRP D 1 299 ? 158.526 126.835 166.255 1.00 88.05  ? 246 TRP A CB  1 
ATOM   10093 C  CG  . TRP D 1 299 ? 159.867 126.367 165.809 1.00 90.67  ? 246 TRP A CG  1 
ATOM   10094 C  CD1 . TRP D 1 299 ? 161.068 126.664 166.379 1.00 93.20  ? 246 TRP A CD1 1 
ATOM   10095 C  CD2 . TRP D 1 299 ? 160.149 125.496 164.710 1.00 95.33  ? 246 TRP A CD2 1 
ATOM   10096 N  NE1 . TRP D 1 299 ? 162.083 126.038 165.699 1.00 93.52  ? 246 TRP A NE1 1 
ATOM   10097 C  CE2 . TRP D 1 299 ? 161.544 125.315 164.669 1.00 98.35  ? 246 TRP A CE2 1 
ATOM   10098 C  CE3 . TRP D 1 299 ? 159.357 124.855 163.754 1.00 92.14  ? 246 TRP A CE3 1 
ATOM   10099 C  CZ2 . TRP D 1 299 ? 162.164 124.522 163.709 1.00 99.25  ? 246 TRP A CZ2 1 
ATOM   10100 C  CZ3 . TRP D 1 299 ? 159.974 124.068 162.803 1.00 93.02  ? 246 TRP A CZ3 1 
ATOM   10101 C  CH2 . TRP D 1 299 ? 161.363 123.907 162.787 1.00 96.33  ? 246 TRP A CH2 1 
ATOM   10102 N  N   . LEU D 1 300 ? 155.440 126.207 167.696 1.00 90.68  ? 247 LEU A N   1 
ATOM   10103 C  CA  . LEU D 1 300 ? 154.431 126.681 168.630 1.00 94.16  ? 247 LEU A CA  1 
ATOM   10104 C  C   . LEU D 1 300 ? 154.530 125.901 169.933 1.00 102.92 ? 247 LEU A C   1 
ATOM   10105 O  O   . LEU D 1 300 ? 154.833 124.705 169.935 1.00 102.90 ? 247 LEU A O   1 
ATOM   10106 C  CB  . LEU D 1 300 ? 153.035 126.537 168.029 1.00 88.59  ? 247 LEU A CB  1 
ATOM   10107 C  CG  . LEU D 1 300 ? 152.772 127.339 166.755 1.00 86.34  ? 247 LEU A CG  1 
ATOM   10108 C  CD1 . LEU D 1 300 ? 151.329 127.201 166.323 1.00 82.40  ? 247 LEU A CD1 1 
ATOM   10109 C  CD2 . LEU D 1 300 ? 153.132 128.796 166.958 1.00 83.91  ? 247 LEU A CD2 1 
ATOM   10110 N  N   . ASN D 1 301 ? 154.293 126.588 171.047 1.00 107.11 ? 248 ASN A N   1 
ATOM   10111 C  CA  . ASN D 1 301 ? 154.373 125.934 172.345 1.00 109.53 ? 248 ASN A CA  1 
ATOM   10112 C  C   . ASN D 1 301 ? 153.317 124.842 172.453 1.00 110.88 ? 248 ASN A C   1 
ATOM   10113 O  O   . ASN D 1 301 ? 152.165 125.024 172.050 1.00 106.76 ? 248 ASN A O   1 
ATOM   10114 C  CB  . ASN D 1 301 ? 154.199 126.948 173.474 1.00 109.79 ? 248 ASN A CB  1 
ATOM   10115 C  CG  . ASN D 1 301 ? 154.315 126.311 174.845 1.00 118.28 ? 248 ASN A CG  1 
ATOM   10116 O  OD1 . ASN D 1 301 ? 155.018 125.316 175.021 1.00 119.31 ? 248 ASN A OD1 1 
ATOM   10117 N  ND2 . ASN D 1 301 ? 153.614 126.874 175.822 1.00 118.99 ? 248 ASN A ND2 1 
ATOM   10118 N  N   . ARG D 1 302 ? 153.720 123.698 173.007 1.00 113.69 ? 249 ARG A N   1 
ATOM   10119 C  CA  . ARG D 1 302 ? 152.835 122.542 173.072 1.00 113.93 ? 249 ARG A CA  1 
ATOM   10120 C  C   . ARG D 1 302 ? 151.605 122.793 173.931 1.00 112.44 ? 249 ARG A C   1 
ATOM   10121 O  O   . ARG D 1 302 ? 150.594 122.105 173.755 1.00 109.00 ? 249 ARG A O   1 
ATOM   10122 C  CB  . ARG D 1 302 ? 153.603 121.333 173.602 1.00 117.15 ? 249 ARG A CB  1 
ATOM   10123 C  CG  . ARG D 1 302 ? 154.703 120.853 172.675 1.00 115.79 ? 249 ARG A CG  1 
ATOM   10124 C  CD  . ARG D 1 302 ? 155.685 119.943 173.389 1.00 117.68 ? 249 ARG A CD  1 
ATOM   10125 N  NE  . ARG D 1 302 ? 155.021 118.895 174.154 1.00 125.04 ? 249 ARG A NE  1 
ATOM   10126 C  CZ  . ARG D 1 302 ? 154.948 118.865 175.477 1.00 129.83 ? 249 ARG A CZ  1 
ATOM   10127 N  NH1 . ARG D 1 302 ? 155.499 119.809 176.222 1.00 129.23 ? 249 ARG A NH1 1 
ATOM   10128 N  NH2 . ARG D 1 302 ? 154.308 117.860 176.069 1.00 124.50 ? 249 ARG A NH2 1 
ATOM   10129 N  N   . GLU D 1 303 ? 151.671 123.748 174.862 1.00 114.28 ? 250 GLU A N   1 
ATOM   10130 C  CA  . GLU D 1 303 ? 150.502 124.069 175.673 1.00 113.38 ? 250 GLU A CA  1 
ATOM   10131 C  C   . GLU D 1 303 ? 149.390 124.677 174.828 1.00 110.42 ? 250 GLU A C   1 
ATOM   10132 O  O   . GLU D 1 303 ? 148.213 124.348 175.014 1.00 103.08 ? 250 GLU A O   1 
ATOM   10133 C  CB  . GLU D 1 303 ? 150.892 125.020 176.802 1.00 115.86 ? 250 GLU A CB  1 
ATOM   10134 C  CG  . GLU D 1 303 ? 151.967 124.481 177.723 1.00 121.62 ? 250 GLU A CG  1 
ATOM   10135 C  CD  . GLU D 1 303 ? 152.104 125.299 178.990 1.00 130.88 ? 250 GLU A CD  1 
ATOM   10136 O  OE1 . GLU D 1 303 ? 151.275 126.207 179.203 1.00 134.76 ? 250 GLU A OE1 1 
ATOM   10137 O  OE2 . GLU D 1 303 ? 153.040 125.036 179.773 1.00 135.20 ? 250 GLU A OE2 1 
ATOM   10138 N  N   . SER D 1 304 ? 149.742 125.555 173.890 1.00 111.01 ? 251 SER A N   1 
ATOM   10139 C  CA  . SER D 1 304 ? 148.741 126.219 173.063 1.00 104.61 ? 251 SER A CA  1 
ATOM   10140 C  C   . SER D 1 304 ? 148.164 125.248 172.043 1.00 101.81 ? 251 SER A C   1 
ATOM   10141 O  O   . SER D 1 304 ? 148.419 125.373 170.842 1.00 102.32 ? 251 SER A O   1 
ATOM   10142 C  CB  . SER D 1 304 ? 149.342 127.435 172.360 1.00 100.15 ? 251 SER A CB  1 
ATOM   10143 O  OG  . SER D 1 304 ? 150.337 127.045 171.434 1.00 98.02  ? 251 SER A OG  1 
ATOM   10144 N  N   . VAL D 1 305 ? 147.393 124.270 172.523 1.00 100.79 ? 252 VAL A N   1 
ATOM   10145 C  CA  . VAL D 1 305 ? 146.775 123.297 171.621 1.00 99.06  ? 252 VAL A CA  1 
ATOM   10146 C  C   . VAL D 1 305 ? 145.824 123.950 170.623 1.00 93.90  ? 252 VAL A C   1 
ATOM   10147 O  O   . VAL D 1 305 ? 145.862 123.578 169.437 1.00 91.93  ? 252 VAL A O   1 
ATOM   10148 C  CB  . VAL D 1 305 ? 146.104 122.178 172.438 1.00 98.10  ? 252 VAL A CB  1 
ATOM   10149 C  CG1 . VAL D 1 305 ? 145.352 121.223 171.529 1.00 89.81  ? 252 VAL A CG1 1 
ATOM   10150 C  CG2 . VAL D 1 305 ? 147.149 121.431 173.253 1.00 99.80  ? 252 VAL A CG2 1 
ATOM   10151 N  N   . PRO D 1 306 ? 144.942 124.882 171.013 1.00 92.23  ? 253 PRO A N   1 
ATOM   10152 C  CA  . PRO D 1 306 ? 144.063 125.495 170.003 1.00 90.35  ? 253 PRO A CA  1 
ATOM   10153 C  C   . PRO D 1 306 ? 144.812 126.160 168.861 1.00 87.74  ? 253 PRO A C   1 
ATOM   10154 O  O   . PRO D 1 306 ? 144.389 126.045 167.704 1.00 84.76  ? 253 PRO A O   1 
ATOM   10155 C  CB  . PRO D 1 306 ? 143.257 126.513 170.820 1.00 87.72  ? 253 PRO A CB  1 
ATOM   10156 C  CG  . PRO D 1 306 ? 143.248 125.961 172.188 1.00 90.14  ? 253 PRO A CG  1 
ATOM   10157 C  CD  . PRO D 1 306 ? 144.594 125.340 172.371 1.00 92.20  ? 253 PRO A CD  1 
ATOM   10158 N  N   . ALA D 1 307 ? 145.923 126.839 169.149 1.00 88.61  ? 254 ALA A N   1 
ATOM   10159 C  CA  . ALA D 1 307 ? 146.673 127.498 168.087 1.00 86.72  ? 254 ALA A CA  1 
ATOM   10160 C  C   . ALA D 1 307 ? 147.212 126.489 167.083 1.00 83.58  ? 254 ALA A C   1 
ATOM   10161 O  O   . ALA D 1 307 ? 147.149 126.714 165.870 1.00 81.95  ? 254 ALA A O   1 
ATOM   10162 C  CB  . ALA D 1 307 ? 147.812 128.325 168.680 1.00 86.49  ? 254 ALA A CB  1 
ATOM   10163 N  N   . ARG D 1 308 ? 147.737 125.364 167.567 1.00 84.83  ? 255 ARG A N   1 
ATOM   10164 C  CA  . ARG D 1 308 ? 148.284 124.365 166.656 1.00 81.97  ? 255 ARG A CA  1 
ATOM   10165 C  C   . ARG D 1 308 ? 147.183 123.660 165.871 1.00 79.71  ? 255 ARG A C   1 
ATOM   10166 O  O   . ARG D 1 308 ? 147.373 123.329 164.696 1.00 78.75  ? 255 ARG A O   1 
ATOM   10167 C  CB  . ARG D 1 308 ? 149.138 123.367 167.428 1.00 80.75  ? 255 ARG A CB  1 
ATOM   10168 C  CG  . ARG D 1 308 ? 150.329 124.007 168.104 1.00 84.02  ? 255 ARG A CG  1 
ATOM   10169 C  CD  . ARG D 1 308 ? 151.266 122.979 168.710 1.00 90.73  ? 255 ARG A CD  1 
ATOM   10170 N  NE  . ARG D 1 308 ? 151.759 122.026 167.724 1.00 90.43  ? 255 ARG A NE  1 
ATOM   10171 C  CZ  . ARG D 1 308 ? 152.795 121.223 167.916 1.00 91.58  ? 255 ARG A CZ  1 
ATOM   10172 N  NH1 . ARG D 1 308 ? 153.504 121.265 169.031 1.00 95.36  ? 255 ARG A NH1 1 
ATOM   10173 N  NH2 . ARG D 1 308 ? 153.130 120.356 166.966 1.00 91.24  ? 255 ARG A NH2 1 
ATOM   10174 N  N   . THR D 1 309 ? 146.026 123.421 166.495 1.00 78.55  ? 256 THR A N   1 
ATOM   10175 C  CA  . THR D 1 309 ? 144.905 122.867 165.739 1.00 78.72  ? 256 THR A CA  1 
ATOM   10176 C  C   . THR D 1 309 ? 144.481 123.814 164.625 1.00 77.08  ? 256 THR A C   1 
ATOM   10177 O  O   . THR D 1 309 ? 144.229 123.383 163.492 1.00 75.64  ? 256 THR A O   1 
ATOM   10178 C  CB  . THR D 1 309 ? 143.718 122.574 166.655 1.00 79.09  ? 256 THR A CB  1 
ATOM   10179 O  OG1 . THR D 1 309 ? 143.329 123.772 167.334 1.00 86.31  ? 256 THR A OG1 1 
ATOM   10180 C  CG2 . THR D 1 309 ? 144.069 121.512 167.670 1.00 80.55  ? 256 THR A CG2 1 
ATOM   10181 N  N   . VAL D 1 310 ? 144.404 125.112 164.926 1.00 77.16  ? 257 VAL A N   1 
ATOM   10182 C  CA  . VAL D 1 310 ? 144.032 126.089 163.909 1.00 72.44  ? 257 VAL A CA  1 
ATOM   10183 C  C   . VAL D 1 310 ? 145.068 126.123 162.793 1.00 70.43  ? 257 VAL A C   1 
ATOM   10184 O  O   . VAL D 1 310 ? 144.719 126.177 161.611 1.00 69.79  ? 257 VAL A O   1 
ATOM   10185 C  CB  . VAL D 1 310 ? 143.830 127.478 164.541 1.00 71.59  ? 257 VAL A CB  1 
ATOM   10186 C  CG1 . VAL D 1 310 ? 143.619 128.520 163.466 1.00 70.78  ? 257 VAL A CG1 1 
ATOM   10187 C  CG2 . VAL D 1 310 ? 142.638 127.464 165.480 1.00 71.95  ? 257 VAL A CG2 1 
ATOM   10188 N  N   . PHE D 1 311 ? 146.354 126.085 163.143 1.00 70.29  ? 258 PHE A N   1 
ATOM   10189 C  CA  . PHE D 1 311 ? 147.401 126.091 162.123 1.00 68.07  ? 258 PHE A CA  1 
ATOM   10190 C  C   . PHE D 1 311 ? 147.301 124.873 161.212 1.00 68.20  ? 258 PHE A C   1 
ATOM   10191 O  O   . PHE D 1 311 ? 147.375 124.992 159.981 1.00 69.66  ? 258 PHE A O   1 
ATOM   10192 C  CB  . PHE D 1 311 ? 148.774 126.136 162.786 1.00 68.91  ? 258 PHE A CB  1 
ATOM   10193 C  CG  . PHE D 1 311 ? 149.425 127.477 162.741 1.00 72.96  ? 258 PHE A CG  1 
ATOM   10194 C  CD1 . PHE D 1 311 ? 149.050 128.473 163.620 1.00 79.00  ? 258 PHE A CD1 1 
ATOM   10195 C  CD2 . PHE D 1 311 ? 150.426 127.736 161.831 1.00 72.98  ? 258 PHE A CD2 1 
ATOM   10196 C  CE1 . PHE D 1 311 ? 149.656 129.706 163.584 1.00 80.01  ? 258 PHE A CE1 1 
ATOM   10197 C  CE2 . PHE D 1 311 ? 151.036 128.967 161.791 1.00 78.36  ? 258 PHE A CE2 1 
ATOM   10198 C  CZ  . PHE D 1 311 ? 150.648 129.955 162.668 1.00 81.28  ? 258 PHE A CZ  1 
ATOM   10199 N  N   . GLY D 1 312 ? 147.144 123.689 161.802 1.00 67.16  ? 259 GLY A N   1 
ATOM   10200 C  CA  . GLY D 1 312 ? 147.071 122.482 160.997 1.00 61.52  ? 259 GLY A CA  1 
ATOM   10201 C  C   . GLY D 1 312 ? 145.861 122.470 160.086 1.00 62.73  ? 259 GLY A C   1 
ATOM   10202 O  O   . GLY D 1 312 ? 145.960 122.138 158.900 1.00 63.63  ? 259 GLY A O   1 
ATOM   10203 N  N   . VAL D 1 313 ? 144.700 122.843 160.626 1.00 65.69  ? 260 VAL A N   1 
ATOM   10204 C  CA  . VAL D 1 313 ? 143.489 122.882 159.815 1.00 63.26  ? 260 VAL A CA  1 
ATOM   10205 C  C   . VAL D 1 313 ? 143.617 123.923 158.711 1.00 62.60  ? 260 VAL A C   1 
ATOM   10206 O  O   . VAL D 1 313 ? 143.200 123.691 157.570 1.00 65.46  ? 260 VAL A O   1 
ATOM   10207 C  CB  . VAL D 1 313 ? 142.266 123.136 160.712 1.00 60.24  ? 260 VAL A CB  1 
ATOM   10208 C  CG1 . VAL D 1 313 ? 141.046 123.435 159.876 1.00 59.83  ? 260 VAL A CG1 1 
ATOM   10209 C  CG2 . VAL D 1 313 ? 142.020 121.934 161.593 1.00 58.44  ? 260 VAL A CG2 1 
ATOM   10210 N  N   . THR D 1 314 ? 144.204 125.080 159.024 1.00 61.93  ? 261 THR A N   1 
ATOM   10211 C  CA  . THR D 1 314 ? 144.390 126.121 158.020 1.00 60.50  ? 261 THR A CA  1 
ATOM   10212 C  C   . THR D 1 314 ? 145.236 125.616 156.864 1.00 57.64  ? 261 THR A C   1 
ATOM   10213 O  O   . THR D 1 314 ? 144.874 125.786 155.694 1.00 55.57  ? 261 THR A O   1 
ATOM   10214 C  CB  . THR D 1 314 ? 145.046 127.348 158.653 1.00 61.53  ? 261 THR A CB  1 
ATOM   10215 O  OG1 . THR D 1 314 ? 144.272 127.787 159.775 1.00 68.33  ? 261 THR A OG1 1 
ATOM   10216 C  CG2 . THR D 1 314 ? 145.143 128.474 157.647 1.00 53.72  ? 261 THR A CG2 1 
ATOM   10217 N  N   . THR D 1 315 ? 146.372 124.989 157.172 1.00 57.64  ? 262 THR A N   1 
ATOM   10218 C  CA  . THR D 1 315 ? 147.250 124.525 156.103 1.00 55.38  ? 262 THR A CA  1 
ATOM   10219 C  C   . THR D 1 315 ? 146.604 123.405 155.296 1.00 53.36  ? 262 THR A C   1 
ATOM   10220 O  O   . THR D 1 315 ? 146.726 123.375 154.065 1.00 56.22  ? 262 THR A O   1 
ATOM   10221 C  CB  . THR D 1 315 ? 148.590 124.082 156.673 1.00 51.34  ? 262 THR A CB  1 
ATOM   10222 O  OG1 . THR D 1 315 ? 148.386 122.997 157.580 1.00 59.07  ? 262 THR A OG1 1 
ATOM   10223 C  CG2 . THR D 1 315 ? 149.233 125.233 157.409 1.00 51.60  ? 262 THR A CG2 1 
ATOM   10224 N  N   . VAL D 1 316 ? 145.903 122.483 155.961 1.00 52.37  ? 263 VAL A N   1 
ATOM   10225 C  CA  . VAL D 1 316 ? 145.247 121.397 155.234 1.00 53.15  ? 263 VAL A CA  1 
ATOM   10226 C  C   . VAL D 1 316 ? 144.202 121.954 154.277 1.00 52.51  ? 263 VAL A C   1 
ATOM   10227 O  O   . VAL D 1 316 ? 144.125 121.552 153.111 1.00 54.96  ? 263 VAL A O   1 
ATOM   10228 C  CB  . VAL D 1 316 ? 144.628 120.383 156.212 1.00 54.05  ? 263 VAL A CB  1 
ATOM   10229 C  CG1 . VAL D 1 316 ? 143.695 119.461 155.474 1.00 54.31  ? 263 VAL A CG1 1 
ATOM   10230 C  CG2 . VAL D 1 316 ? 145.705 119.576 156.893 1.00 58.32  ? 263 VAL A CG2 1 
ATOM   10231 N  N   . LEU D 1 317 ? 143.384 122.893 154.752 1.00 51.84  ? 264 LEU A N   1 
ATOM   10232 C  CA  . LEU D 1 317 ? 142.329 123.440 153.907 1.00 52.45  ? 264 LEU A CA  1 
ATOM   10233 C  C   . LEU D 1 317 ? 142.899 124.261 152.757 1.00 54.26  ? 264 LEU A C   1 
ATOM   10234 O  O   . LEU D 1 317 ? 142.389 124.202 151.631 1.00 56.51  ? 264 LEU A O   1 
ATOM   10235 C  CB  . LEU D 1 317 ? 141.372 124.274 154.751 1.00 52.23  ? 264 LEU A CB  1 
ATOM   10236 C  CG  . LEU D 1 317 ? 140.588 123.467 155.782 1.00 48.79  ? 264 LEU A CG  1 
ATOM   10237 C  CD1 . LEU D 1 317 ? 139.713 124.381 156.594 1.00 53.64  ? 264 LEU A CD1 1 
ATOM   10238 C  CD2 . LEU D 1 317 ? 139.765 122.399 155.098 1.00 44.24  ? 264 LEU A CD2 1 
ATOM   10239 N  N   . THR D 1 318 ? 143.955 125.035 153.020 1.00 50.90  ? 265 THR A N   1 
ATOM   10240 C  CA  . THR D 1 318 ? 144.593 125.805 151.960 1.00 48.06  ? 265 THR A CA  1 
ATOM   10241 C  C   . THR D 1 318 ? 145.146 124.888 150.881 1.00 46.98  ? 265 THR A C   1 
ATOM   10242 O  O   . THR D 1 318 ? 144.963 125.132 149.682 1.00 44.70  ? 265 THR A O   1 
ATOM   10243 C  CB  . THR D 1 318 ? 145.700 126.672 152.548 1.00 45.25  ? 265 THR A CB  1 
ATOM   10244 O  OG1 . THR D 1 318 ? 145.134 127.614 153.464 1.00 48.87  ? 265 THR A OG1 1 
ATOM   10245 C  CG2 . THR D 1 318 ? 146.436 127.412 151.457 1.00 44.69  ? 265 THR A CG2 1 
ATOM   10246 N  N   . MET D 1 319 ? 145.827 123.818 151.292 1.00 50.39  ? 266 MET A N   1 
ATOM   10247 C  CA  . MET D 1 319 ? 146.363 122.872 150.325 1.00 49.44  ? 266 MET A CA  1 
ATOM   10248 C  C   . MET D 1 319 ? 145.245 122.194 149.549 1.00 50.24  ? 266 MET A C   1 
ATOM   10249 O  O   . MET D 1 319 ? 145.380 121.937 148.349 1.00 51.83  ? 266 MET A O   1 
ATOM   10250 C  CB  . MET D 1 319 ? 147.235 121.843 151.040 1.00 54.45  ? 266 MET A CB  1 
ATOM   10251 C  CG  . MET D 1 319 ? 147.935 120.883 150.116 1.00 59.63  ? 266 MET A CG  1 
ATOM   10252 S  SD  . MET D 1 319 ? 149.229 121.665 149.153 1.00 65.59  ? 266 MET A SD  1 
ATOM   10253 C  CE  . MET D 1 319 ? 149.168 120.641 147.692 1.00 59.63  ? 266 MET A CE  1 
ATOM   10254 N  N   . THR D 1 320 ? 144.128 121.903 150.214 1.00 54.04  ? 267 THR A N   1 
ATOM   10255 C  CA  . THR D 1 320 ? 142.994 121.300 149.523 1.00 52.00  ? 267 THR A CA  1 
ATOM   10256 C  C   . THR D 1 320 ? 142.467 122.214 148.426 1.00 49.40  ? 267 THR A C   1 
ATOM   10257 O  O   . THR D 1 320 ? 142.256 121.779 147.287 1.00 48.98  ? 267 THR A O   1 
ATOM   10258 C  CB  . THR D 1 320 ? 141.889 120.972 150.525 1.00 50.25  ? 267 THR A CB  1 
ATOM   10259 O  OG1 . THR D 1 320 ? 142.355 119.966 151.430 1.00 62.14  ? 267 THR A OG1 1 
ATOM   10260 C  CG2 . THR D 1 320 ? 140.655 120.465 149.812 1.00 46.65  ? 267 THR A CG2 1 
ATOM   10261 N  N   . THR D 1 321 ? 142.251 123.490 148.750 1.00 50.00  ? 268 THR A N   1 
ATOM   10262 C  CA  . THR D 1 321 ? 141.713 124.416 147.754 1.00 49.42  ? 268 THR A CA  1 
ATOM   10263 C  C   . THR D 1 321 ? 142.693 124.628 146.607 1.00 48.96  ? 268 THR A C   1 
ATOM   10264 O  O   . THR D 1 321 ? 142.293 124.675 145.439 1.00 49.77  ? 268 THR A O   1 
ATOM   10265 C  CB  . THR D 1 321 ? 141.347 125.750 148.399 1.00 52.28  ? 268 THR A CB  1 
ATOM   10266 O  OG1 . THR D 1 321 ? 142.496 126.296 149.052 1.00 59.37  ? 268 THR A OG1 1 
ATOM   10267 C  CG2 . THR D 1 321 ? 140.237 125.561 149.406 1.00 49.56  ? 268 THR A CG2 1 
ATOM   10268 N  N   . LEU D 1 322 ? 143.986 124.760 146.919 1.00 47.60  ? 269 LEU A N   1 
ATOM   10269 C  CA  . LEU D 1 322 ? 144.977 124.920 145.859 1.00 42.70  ? 269 LEU A CA  1 
ATOM   10270 C  C   . LEU D 1 322 ? 145.022 123.698 144.953 1.00 46.68  ? 269 LEU A C   1 
ATOM   10271 O  O   . LEU D 1 322 ? 145.106 123.830 143.729 1.00 52.05  ? 269 LEU A O   1 
ATOM   10272 C  CB  . LEU D 1 322 ? 146.356 125.188 146.453 1.00 44.70  ? 269 LEU A CB  1 
ATOM   10273 C  CG  . LEU D 1 322 ? 146.542 126.513 147.179 1.00 42.92  ? 269 LEU A CG  1 
ATOM   10274 C  CD1 . LEU D 1 322 ? 147.924 126.585 147.765 1.00 39.71  ? 269 LEU A CD1 1 
ATOM   10275 C  CD2 . LEU D 1 322 ? 146.312 127.664 146.239 1.00 43.39  ? 269 LEU A CD2 1 
ATOM   10276 N  N   . SER D 1 323 ? 144.973 122.497 145.533 1.00 49.19  ? 270 SER A N   1 
ATOM   10277 C  CA  . SER D 1 323 ? 144.993 121.286 144.723 1.00 49.71  ? 270 SER A CA  1 
ATOM   10278 C  C   . SER D 1 323 ? 143.766 121.196 143.828 1.00 55.37  ? 270 SER A C   1 
ATOM   10279 O  O   . SER D 1 323 ? 143.873 120.838 142.647 1.00 61.99  ? 270 SER A O   1 
ATOM   10280 C  CB  . SER D 1 323 ? 145.080 120.061 145.625 1.00 51.28  ? 270 SER A CB  1 
ATOM   10281 O  OG  . SER D 1 323 ? 145.036 118.873 144.860 1.00 61.86  ? 270 SER A OG  1 
ATOM   10282 N  N   . ILE D 1 324 ? 142.589 121.514 144.369 1.00 54.43  ? 271 ILE A N   1 
ATOM   10283 C  CA  . ILE D 1 324 ? 141.371 121.462 143.566 1.00 52.55  ? 271 ILE A CA  1 
ATOM   10284 C  C   . ILE D 1 324 ? 141.437 122.477 142.434 1.00 57.46  ? 271 ILE A C   1 
ATOM   10285 O  O   . ILE D 1 324 ? 141.016 122.197 141.306 1.00 63.80  ? 271 ILE A O   1 
ATOM   10286 C  CB  . ILE D 1 324 ? 140.130 121.675 144.453 1.00 49.50  ? 271 ILE A CB  1 
ATOM   10287 C  CG1 . ILE D 1 324 ? 140.000 120.535 145.457 1.00 50.64  ? 271 ILE A CG1 1 
ATOM   10288 C  CG2 . ILE D 1 324 ? 138.876 121.754 143.612 1.00 43.97  ? 271 ILE A CG2 1 
ATOM   10289 C  CD1 . ILE D 1 324 ? 139.829 119.188 144.817 1.00 54.26  ? 271 ILE A CD1 1 
ATOM   10290 N  N   . SER D 1 325 ? 141.964 123.671 142.711 1.00 53.38  ? 272 SER A N   1 
ATOM   10291 C  CA  . SER D 1 325 ? 142.114 124.669 141.656 1.00 52.92  ? 272 SER A CA  1 
ATOM   10292 C  C   . SER D 1 325 ? 143.081 124.201 140.579 1.00 58.13  ? 272 SER A C   1 
ATOM   10293 O  O   . SER D 1 325 ? 142.817 124.368 139.384 1.00 64.92  ? 272 SER A O   1 
ATOM   10294 C  CB  . SER D 1 325 ? 142.590 125.992 142.248 1.00 53.70  ? 272 SER A CB  1 
ATOM   10295 O  OG  . SER D 1 325 ? 142.869 126.926 141.226 1.00 54.64  ? 272 SER A OG  1 
ATOM   10296 N  N   . ALA D 1 326 ? 144.210 123.617 140.982 1.00 58.54  ? 273 ALA A N   1 
ATOM   10297 C  CA  . ALA D 1 326 ? 145.212 123.191 140.012 1.00 58.54  ? 273 ALA A CA  1 
ATOM   10298 C  C   . ALA D 1 326 ? 144.694 122.057 139.142 1.00 66.11  ? 273 ALA A C   1 
ATOM   10299 O  O   . ALA D 1 326 ? 145.043 121.962 137.962 1.00 71.21  ? 273 ALA A O   1 
ATOM   10300 C  CB  . ALA D 1 326 ? 146.490 122.768 140.728 1.00 47.51  ? 273 ALA A CB  1 
ATOM   10301 N  N   . ARG D 1 327 ? 143.871 121.178 139.713 1.00 67.30  ? 274 ARG A N   1 
ATOM   10302 C  CA  . ARG D 1 327 ? 143.323 120.073 138.935 1.00 68.45  ? 274 ARG A CA  1 
ATOM   10303 C  C   . ARG D 1 327 ? 142.365 120.569 137.860 1.00 71.76  ? 274 ARG A C   1 
ATOM   10304 O  O   . ARG D 1 327 ? 142.177 119.907 136.834 1.00 75.48  ? 274 ARG A O   1 
ATOM   10305 C  CB  . ARG D 1 327 ? 142.622 119.088 139.865 1.00 69.12  ? 274 ARG A CB  1 
ATOM   10306 C  CG  . ARG D 1 327 ? 143.316 117.753 139.970 1.00 73.86  ? 274 ARG A CG  1 
ATOM   10307 C  CD  . ARG D 1 327 ? 143.195 117.004 138.664 1.00 80.41  ? 274 ARG A CD  1 
ATOM   10308 N  NE  . ARG D 1 327 ? 144.061 115.835 138.623 1.00 84.86  ? 274 ARG A NE  1 
ATOM   10309 C  CZ  . ARG D 1 327 ? 144.182 115.036 137.574 1.00 85.90  ? 274 ARG A CZ  1 
ATOM   10310 N  NH1 . ARG D 1 327 ? 143.491 115.243 136.466 1.00 83.17  ? 274 ARG A NH1 1 
ATOM   10311 N  NH2 . ARG D 1 327 ? 145.020 114.007 137.637 1.00 86.53  ? 274 ARG A NH2 1 
ATOM   10312 N  N   . ASN D 1 328 ? 141.750 121.732 138.076 1.00 72.53  ? 275 ASN A N   1 
ATOM   10313 C  CA  . ASN D 1 328 ? 140.744 122.232 137.146 1.00 73.62  ? 275 ASN A CA  1 
ATOM   10314 C  C   . ASN D 1 328 ? 141.355 122.601 135.800 1.00 74.61  ? 275 ASN A C   1 
ATOM   10315 O  O   . ASN D 1 328 ? 140.744 122.371 134.751 1.00 76.87  ? 275 ASN A O   1 
ATOM   10316 C  CB  . ASN D 1 328 ? 140.024 123.433 137.756 1.00 74.96  ? 275 ASN A CB  1 
ATOM   10317 C  CG  . ASN D 1 328 ? 139.067 124.098 136.787 1.00 88.10  ? 275 ASN A CG  1 
ATOM   10318 O  OD1 . ASN D 1 328 ? 137.887 123.761 136.734 1.00 95.05  ? 275 ASN A OD1 1 
ATOM   10319 N  ND2 . ASN D 1 328 ? 139.572 125.056 136.019 1.00 87.62  ? 275 ASN A ND2 1 
ATOM   10320 N  N   . SER D 1 329 ? 142.545 123.196 135.806 1.00 74.04  ? 276 SER A N   1 
ATOM   10321 C  CA  . SER D 1 329 ? 143.182 123.632 134.572 1.00 80.43  ? 276 SER A CA  1 
ATOM   10322 C  C   . SER D 1 329 ? 144.140 122.600 133.993 1.00 84.48  ? 276 SER A C   1 
ATOM   10323 O  O   . SER D 1 329 ? 144.788 122.879 132.979 1.00 88.10  ? 276 SER A O   1 
ATOM   10324 C  CB  . SER D 1 329 ? 143.924 124.952 134.798 1.00 84.19  ? 276 SER A CB  1 
ATOM   10325 O  OG  . SER D 1 329 ? 144.881 124.827 135.833 1.00 86.39  ? 276 SER A OG  1 
ATOM   10326 N  N   . LEU D 1 330 ? 144.255 121.433 134.613 1.00 78.52  ? 277 LEU A N   1 
ATOM   10327 C  CA  . LEU D 1 330 ? 145.089 120.375 134.077 1.00 71.80  ? 277 LEU A CA  1 
ATOM   10328 C  C   . LEU D 1 330 ? 144.447 119.780 132.825 1.00 75.89  ? 277 LEU A C   1 
ATOM   10329 O  O   . LEU D 1 330 ? 143.221 119.698 132.729 1.00 74.18  ? 277 LEU A O   1 
ATOM   10330 C  CB  . LEU D 1 330 ? 145.287 119.288 135.128 1.00 73.82  ? 277 LEU A CB  1 
ATOM   10331 C  CG  . LEU D 1 330 ? 146.475 118.343 135.002 1.00 75.33  ? 277 LEU A CG  1 
ATOM   10332 C  CD1 . LEU D 1 330 ? 147.755 119.111 135.196 1.00 70.67  ? 277 LEU A CD1 1 
ATOM   10333 C  CD2 . LEU D 1 330 ? 146.367 117.235 136.017 1.00 73.29  ? 277 LEU A CD2 1 
ATOM   10334 N  N   . PRO D 1 331 ? 145.251 119.379 131.842 1.00 77.94  ? 278 PRO A N   1 
ATOM   10335 C  CA  . PRO D 1 331 ? 144.699 118.667 130.685 1.00 73.20  ? 278 PRO A CA  1 
ATOM   10336 C  C   . PRO D 1 331 ? 144.119 117.317 131.082 1.00 70.98  ? 278 PRO A C   1 
ATOM   10337 O  O   . PRO D 1 331 ? 144.600 116.652 132.001 1.00 68.99  ? 278 PRO A O   1 
ATOM   10338 C  CB  . PRO D 1 331 ? 145.910 118.506 129.758 1.00 71.29  ? 278 PRO A CB  1 
ATOM   10339 C  CG  . PRO D 1 331 ? 146.842 119.584 130.170 1.00 67.98  ? 278 PRO A CG  1 
ATOM   10340 C  CD  . PRO D 1 331 ? 146.668 119.723 131.648 1.00 71.65  ? 278 PRO A CD  1 
ATOM   10341 N  N   . LYS D 1 332 ? 143.078 116.907 130.360 1.00 66.62  ? 279 LYS A N   1 
ATOM   10342 C  CA  . LYS D 1 332 ? 142.299 115.721 130.716 1.00 62.53  ? 279 LYS A CA  1 
ATOM   10343 C  C   . LYS D 1 332 ? 142.945 114.466 130.132 1.00 61.55  ? 279 LYS A C   1 
ATOM   10344 O  O   . LYS D 1 332 ? 142.477 113.871 129.161 1.00 58.71  ? 279 LYS A O   1 
ATOM   10345 C  CB  . LYS D 1 332 ? 140.861 115.879 130.245 1.00 60.65  ? 279 LYS A CB  1 
ATOM   10346 C  CG  . LYS D 1 332 ? 140.159 117.095 130.827 1.00 68.70  ? 279 LYS A CG  1 
ATOM   10347 C  CD  . LYS D 1 332 ? 138.792 117.297 130.198 1.00 80.99  ? 279 LYS A CD  1 
ATOM   10348 C  CE  . LYS D 1 332 ? 138.225 118.662 130.538 1.00 79.20  ? 279 LYS A CE  1 
ATOM   10349 N  NZ  . LYS D 1 332 ? 137.021 118.972 129.722 1.00 74.17  ? 279 LYS A NZ  1 
ATOM   10350 N  N   . VAL D 1 333 ? 144.037 114.055 130.763 1.00 62.30  ? 280 VAL A N   1 
ATOM   10351 C  CA  . VAL D 1 333 ? 144.731 112.843 130.389 1.00 58.35  ? 280 VAL A CA  1 
ATOM   10352 C  C   . VAL D 1 333 ? 144.448 111.771 131.433 1.00 58.32  ? 280 VAL A C   1 
ATOM   10353 O  O   . VAL D 1 333 ? 143.954 112.047 132.522 1.00 60.49  ? 280 VAL A O   1 
ATOM   10354 C  CB  . VAL D 1 333 ? 146.247 113.075 130.216 1.00 54.87  ? 280 VAL A CB  1 
ATOM   10355 C  CG1 . VAL D 1 333 ? 146.486 114.222 129.269 1.00 55.94  ? 280 VAL A CG1 1 
ATOM   10356 C  CG2 . VAL D 1 333 ? 146.905 113.336 131.550 1.00 49.21  ? 280 VAL A CG2 1 
ATOM   10357 N  N   . ALA D 1 334 ? 144.764 110.522 131.095 1.00 57.83  ? 281 ALA A N   1 
ATOM   10358 C  CA  . ALA D 1 334 ? 144.443 109.372 131.929 1.00 53.79  ? 281 ALA A CA  1 
ATOM   10359 C  C   . ALA D 1 334 ? 145.656 108.837 132.676 1.00 51.87  ? 281 ALA A C   1 
ATOM   10360 O  O   . ALA D 1 334 ? 145.775 107.626 132.877 1.00 57.05  ? 281 ALA A O   1 
ATOM   10361 C  CB  . ALA D 1 334 ? 143.815 108.268 131.084 1.00 51.12  ? 281 ALA A CB  1 
ATOM   10362 N  N   . TYR D 1 335 ? 146.565 109.714 133.081 1.00 50.09  ? 282 TYR A N   1 
ATOM   10363 C  CA  . TYR D 1 335 ? 147.720 109.317 133.867 1.00 50.73  ? 282 TYR A CA  1 
ATOM   10364 C  C   . TYR D 1 335 ? 148.123 110.492 134.746 1.00 53.00  ? 282 TYR A C   1 
ATOM   10365 O  O   . TYR D 1 335 ? 147.442 111.518 134.796 1.00 58.78  ? 282 TYR A O   1 
ATOM   10366 C  CB  . TYR D 1 335 ? 148.868 108.842 132.968 1.00 54.39  ? 282 TYR A CB  1 
ATOM   10367 C  CG  . TYR D 1 335 ? 149.117 109.709 131.759 1.00 58.31  ? 282 TYR A CG  1 
ATOM   10368 C  CD1 . TYR D 1 335 ? 149.970 110.799 131.825 1.00 57.62  ? 282 TYR A CD1 1 
ATOM   10369 C  CD2 . TYR D 1 335 ? 148.504 109.433 130.550 1.00 58.72  ? 282 TYR A CD2 1 
ATOM   10370 C  CE1 . TYR D 1 335 ? 150.195 111.591 130.726 1.00 57.76  ? 282 TYR A CE1 1 
ATOM   10371 C  CE2 . TYR D 1 335 ? 148.724 110.220 129.446 1.00 57.51  ? 282 TYR A CE2 1 
ATOM   10372 C  CZ  . TYR D 1 335 ? 149.570 111.296 129.538 1.00 60.13  ? 282 TYR A CZ  1 
ATOM   10373 O  OH  . TYR D 1 335 ? 149.790 112.078 128.433 1.00 62.79  ? 282 TYR A OH  1 
ATOM   10374 N  N   . ALA D 1 336 ? 149.236 110.336 135.447 1.00 50.26  ? 283 ALA A N   1 
ATOM   10375 C  CA  . ALA D 1 336 ? 149.708 111.337 136.390 1.00 53.27  ? 283 ALA A CA  1 
ATOM   10376 C  C   . ALA D 1 336 ? 150.790 112.189 135.742 1.00 57.37  ? 283 ALA A C   1 
ATOM   10377 O  O   . ALA D 1 336 ? 151.734 111.656 135.153 1.00 59.38  ? 283 ALA A O   1 
ATOM   10378 C  CB  . ALA D 1 336 ? 150.243 110.672 137.657 1.00 51.13  ? 283 ALA A CB  1 
ATOM   10379 N  N   . THR D 1 337 ? 150.648 113.505 135.853 1.00 57.54  ? 284 THR A N   1 
ATOM   10380 C  CA  . THR D 1 337 ? 151.642 114.441 135.363 1.00 50.87  ? 284 THR A CA  1 
ATOM   10381 C  C   . THR D 1 337 ? 152.607 114.796 136.490 1.00 53.82  ? 284 THR A C   1 
ATOM   10382 O  O   . THR D 1 337 ? 152.461 114.344 137.625 1.00 60.39  ? 284 THR A O   1 
ATOM   10383 C  CB  . THR D 1 337 ? 150.971 115.691 134.804 1.00 49.93  ? 284 THR A CB  1 
ATOM   10384 O  OG1 . THR D 1 337 ? 150.411 116.452 135.877 1.00 54.40  ? 284 THR A OG1 1 
ATOM   10385 C  CG2 . THR D 1 337 ? 149.861 115.308 133.859 1.00 49.05  ? 284 THR A CG2 1 
ATOM   10386 N  N   . ALA D 1 338 ? 153.612 115.612 136.177 1.00 48.37  ? 285 ALA A N   1 
ATOM   10387 C  CA  . ALA D 1 338 ? 154.562 116.036 137.199 1.00 46.69  ? 285 ALA A CA  1 
ATOM   10388 C  C   . ALA D 1 338 ? 153.889 116.889 138.268 1.00 50.35  ? 285 ALA A C   1 
ATOM   10389 O  O   . ALA D 1 338 ? 154.195 116.757 139.461 1.00 56.23  ? 285 ALA A O   1 
ATOM   10390 C  CB  . ALA D 1 338 ? 155.717 116.793 136.552 1.00 44.06  ? 285 ALA A CB  1 
ATOM   10391 N  N   . MET D 1 339 ? 152.978 117.775 137.865 1.00 46.77  ? 286 MET A N   1 
ATOM   10392 C  CA  . MET D 1 339 ? 152.301 118.619 138.841 1.00 46.30  ? 286 MET A CA  1 
ATOM   10393 C  C   . MET D 1 339 ? 151.441 117.796 139.782 1.00 53.20  ? 286 MET A C   1 
ATOM   10394 O  O   . MET D 1 339 ? 151.315 118.137 140.962 1.00 60.09  ? 286 MET A O   1 
ATOM   10395 C  CB  . MET D 1 339 ? 151.453 119.676 138.137 1.00 45.84  ? 286 MET A CB  1 
ATOM   10396 C  CG  . MET D 1 339 ? 151.271 120.946 138.951 1.00 48.73  ? 286 MET A CG  1 
ATOM   10397 S  SD  . MET D 1 339 ? 150.544 122.291 138.010 1.00 64.15  ? 286 MET A SD  1 
ATOM   10398 C  CE  . MET D 1 339 ? 148.963 121.573 137.597 1.00 63.97  ? 286 MET A CE  1 
ATOM   10399 N  N   . ASP D 1 340 ? 150.847 116.712 139.288 1.00 50.08  ? 287 ASP A N   1 
ATOM   10400 C  CA  . ASP D 1 340 ? 150.089 115.829 140.165 1.00 50.54  ? 287 ASP A CA  1 
ATOM   10401 C  C   . ASP D 1 340 ? 150.983 115.238 141.246 1.00 48.71  ? 287 ASP A C   1 
ATOM   10402 O  O   . ASP D 1 340 ? 150.603 115.185 142.419 1.00 51.04  ? 287 ASP A O   1 
ATOM   10403 C  CB  . ASP D 1 340 ? 149.428 114.726 139.349 1.00 53.96  ? 287 ASP A CB  1 
ATOM   10404 C  CG  . ASP D 1 340 ? 148.319 115.245 138.475 1.00 69.60  ? 287 ASP A CG  1 
ATOM   10405 O  OD1 . ASP D 1 340 ? 147.667 116.230 138.875 1.00 74.75  ? 287 ASP A OD1 1 
ATOM   10406 O  OD2 . ASP D 1 340 ? 148.095 114.673 137.389 1.00 72.47  ? 287 ASP A OD2 1 
ATOM   10407 N  N   . TRP D 1 341 ? 152.180 114.794 140.867 1.00 46.89  ? 288 TRP A N   1 
ATOM   10408 C  CA  . TRP D 1 341 ? 153.102 114.238 141.847 1.00 48.29  ? 288 TRP A CA  1 
ATOM   10409 C  C   . TRP D 1 341 ? 153.529 115.284 142.868 1.00 49.23  ? 288 TRP A C   1 
ATOM   10410 O  O   . TRP D 1 341 ? 153.573 115.004 144.072 1.00 56.01  ? 288 TRP A O   1 
ATOM   10411 C  CB  . TRP D 1 341 ? 154.318 113.648 141.140 1.00 51.92  ? 288 TRP A CB  1 
ATOM   10412 C  CG  . TRP D 1 341 ? 154.025 112.346 140.484 1.00 55.77  ? 288 TRP A CG  1 
ATOM   10413 C  CD1 . TRP D 1 341 ? 153.838 112.120 139.156 1.00 56.76  ? 288 TRP A CD1 1 
ATOM   10414 C  CD2 . TRP D 1 341 ? 153.871 111.083 141.131 1.00 60.29  ? 288 TRP A CD2 1 
ATOM   10415 N  NE1 . TRP D 1 341 ? 153.584 110.793 138.933 1.00 60.18  ? 288 TRP A NE1 1 
ATOM   10416 C  CE2 . TRP D 1 341 ? 153.599 110.133 140.132 1.00 62.98  ? 288 TRP A CE2 1 
ATOM   10417 C  CE3 . TRP D 1 341 ? 153.943 110.661 142.460 1.00 59.21  ? 288 TRP A CE3 1 
ATOM   10418 C  CZ2 . TRP D 1 341 ? 153.396 108.789 140.419 1.00 64.81  ? 288 TRP A CZ2 1 
ATOM   10419 C  CZ3 . TRP D 1 341 ? 153.744 109.328 142.742 1.00 64.98  ? 288 TRP A CZ3 1 
ATOM   10420 C  CH2 . TRP D 1 341 ? 153.473 108.406 141.727 1.00 69.94  ? 288 TRP A CH2 1 
ATOM   10421 N  N   . PHE D 1 342 ? 153.842 116.496 142.412 1.00 48.00  ? 289 PHE A N   1 
ATOM   10422 C  CA  . PHE D 1 342 ? 154.240 117.539 143.351 1.00 48.52  ? 289 PHE A CA  1 
ATOM   10423 C  C   . PHE D 1 342 ? 153.112 117.868 144.321 1.00 51.10  ? 289 PHE A C   1 
ATOM   10424 O  O   . PHE D 1 342 ? 153.340 118.007 145.530 1.00 55.78  ? 289 PHE A O   1 
ATOM   10425 C  CB  . PHE D 1 342 ? 154.677 118.789 142.591 1.00 45.11  ? 289 PHE A CB  1 
ATOM   10426 C  CG  . PHE D 1 342 ? 155.214 119.877 143.468 1.00 49.39  ? 289 PHE A CG  1 
ATOM   10427 C  CD1 . PHE D 1 342 ? 156.545 119.894 143.831 1.00 50.42  ? 289 PHE A CD1 1 
ATOM   10428 C  CD2 . PHE D 1 342 ? 154.396 120.894 143.912 1.00 50.90  ? 289 PHE A CD2 1 
ATOM   10429 C  CE1 . PHE D 1 342 ? 157.044 120.892 144.632 1.00 51.94  ? 289 PHE A CE1 1 
ATOM   10430 C  CE2 . PHE D 1 342 ? 154.893 121.895 144.711 1.00 50.51  ? 289 PHE A CE2 1 
ATOM   10431 C  CZ  . PHE D 1 342 ? 156.220 121.892 145.071 1.00 54.89  ? 289 PHE A CZ  1 
ATOM   10432 N  N   . ILE D 1 343 ? 151.885 117.987 143.813 1.00 46.98  ? 290 ILE A N   1 
ATOM   10433 C  CA  . ILE D 1 343 ? 150.751 118.311 144.672 1.00 47.86  ? 290 ILE A CA  1 
ATOM   10434 C  C   . ILE D 1 343 ? 150.495 117.189 145.665 1.00 51.28  ? 290 ILE A C   1 
ATOM   10435 O  O   . ILE D 1 343 ? 150.208 117.435 146.841 1.00 56.76  ? 290 ILE A O   1 
ATOM   10436 C  CB  . ILE D 1 343 ? 149.509 118.610 143.817 1.00 44.76  ? 290 ILE A CB  1 
ATOM   10437 C  CG1 . ILE D 1 343 ? 149.593 120.019 143.244 1.00 45.13  ? 290 ILE A CG1 1 
ATOM   10438 C  CG2 . ILE D 1 343 ? 148.251 118.452 144.626 1.00 49.09  ? 290 ILE A CG2 1 
ATOM   10439 C  CD1 . ILE D 1 343 ? 148.584 120.280 142.186 1.00 50.62  ? 290 ILE A CD1 1 
ATOM   10440 N  N   . ALA D 1 344 ? 150.596 115.939 145.212 1.00 51.08  ? 291 ALA A N   1 
ATOM   10441 C  CA  . ALA D 1 344 ? 150.396 114.813 146.114 1.00 49.47  ? 291 ALA A CA  1 
ATOM   10442 C  C   . ALA D 1 344 ? 151.437 114.805 147.223 1.00 52.36  ? 291 ALA A C   1 
ATOM   10443 O  O   . ALA D 1 344 ? 151.109 114.543 148.383 1.00 60.83  ? 291 ALA A O   1 
ATOM   10444 C  CB  . ALA D 1 344 ? 150.433 113.503 145.331 1.00 46.49  ? 291 ALA A CB  1 
ATOM   10445 N  N   . VAL D 1 345 ? 152.696 115.096 146.891 1.00 48.49  ? 292 VAL A N   1 
ATOM   10446 C  CA  . VAL D 1 345 ? 153.736 115.106 147.915 1.00 49.58  ? 292 VAL A CA  1 
ATOM   10447 C  C   . VAL D 1 345 ? 153.514 116.244 148.905 1.00 55.08  ? 292 VAL A C   1 
ATOM   10448 O  O   . VAL D 1 345 ? 153.718 116.081 150.114 1.00 59.71  ? 292 VAL A O   1 
ATOM   10449 C  CB  . VAL D 1 345 ? 155.128 115.180 147.272 1.00 51.80  ? 292 VAL A CB  1 
ATOM   10450 C  CG1 . VAL D 1 345 ? 156.185 115.396 148.333 1.00 57.75  ? 292 VAL A CG1 1 
ATOM   10451 C  CG2 . VAL D 1 345 ? 155.410 113.910 146.506 1.00 49.50  ? 292 VAL A CG2 1 
ATOM   10452 N  N   . CYS D 1 346 ? 153.104 117.415 148.417 1.00 52.06  ? 293 CYS A N   1 
ATOM   10453 C  CA  . CYS D 1 346 ? 152.815 118.513 149.332 1.00 52.23  ? 293 CYS A CA  1 
ATOM   10454 C  C   . CYS D 1 346 ? 151.661 118.165 150.263 1.00 55.89  ? 293 CYS A C   1 
ATOM   10455 O  O   . CYS D 1 346 ? 151.700 118.471 151.462 1.00 63.78  ? 293 CYS A O   1 
ATOM   10456 C  CB  . CYS D 1 346 ? 152.508 119.785 148.549 1.00 53.12  ? 293 CYS A CB  1 
ATOM   10457 S  SG  . CYS D 1 346 ? 153.910 120.458 147.655 1.00 59.12  ? 293 CYS A SG  1 
ATOM   10458 N  N   . TYR D 1 347 ? 150.622 117.524 149.728 1.00 54.45  ? 294 TYR A N   1 
ATOM   10459 C  CA  . TYR D 1 347 ? 149.502 117.104 150.561 1.00 52.49  ? 294 TYR A CA  1 
ATOM   10460 C  C   . TYR D 1 347 ? 149.947 116.086 151.599 1.00 55.58  ? 294 TYR A C   1 
ATOM   10461 O  O   . TYR D 1 347 ? 149.507 116.130 152.754 1.00 63.04  ? 294 TYR A O   1 
ATOM   10462 C  CB  . TYR D 1 347 ? 148.393 116.525 149.689 1.00 56.09  ? 294 TYR A CB  1 
ATOM   10463 C  CG  . TYR D 1 347 ? 147.010 116.831 150.189 1.00 62.02  ? 294 TYR A CG  1 
ATOM   10464 C  CD1 . TYR D 1 347 ? 146.481 116.155 151.274 1.00 68.08  ? 294 TYR A CD1 1 
ATOM   10465 C  CD2 . TYR D 1 347 ? 146.231 117.794 149.576 1.00 64.52  ? 294 TYR A CD2 1 
ATOM   10466 C  CE1 . TYR D 1 347 ? 145.217 116.433 151.737 1.00 76.67  ? 294 TYR A CE1 1 
ATOM   10467 C  CE2 . TYR D 1 347 ? 144.965 118.079 150.029 1.00 68.73  ? 294 TYR A CE2 1 
ATOM   10468 C  CZ  . TYR D 1 347 ? 144.462 117.397 151.111 1.00 77.50  ? 294 TYR A CZ  1 
ATOM   10469 O  OH  . TYR D 1 347 ? 143.197 117.677 151.570 1.00 76.78  ? 294 TYR A OH  1 
ATOM   10470 N  N   . ALA D 1 348 ? 150.813 115.155 151.202 1.00 55.36  ? 295 ALA A N   1 
ATOM   10471 C  CA  . ALA D 1 348 ? 151.341 114.186 152.152 1.00 53.43  ? 295 ALA A CA  1 
ATOM   10472 C  C   . ALA D 1 348 ? 152.106 114.877 153.270 1.00 59.84  ? 295 ALA A C   1 
ATOM   10473 O  O   . ALA D 1 348 ? 151.943 114.533 154.442 1.00 67.22  ? 295 ALA A O   1 
ATOM   10474 C  CB  . ALA D 1 348 ? 152.234 113.178 151.433 1.00 46.14  ? 295 ALA A CB  1 
ATOM   10475 N  N   . PHE D 1 349 ? 152.933 115.868 152.931 1.00 56.13  ? 296 PHE A N   1 
ATOM   10476 C  CA  . PHE D 1 349 ? 153.684 116.583 153.961 1.00 55.42  ? 296 PHE A CA  1 
ATOM   10477 C  C   . PHE D 1 349 ? 152.760 117.327 154.917 1.00 62.17  ? 296 PHE A C   1 
ATOM   10478 O  O   . PHE D 1 349 ? 152.975 117.317 156.135 1.00 68.26  ? 296 PHE A O   1 
ATOM   10479 C  CB  . PHE D 1 349 ? 154.668 117.556 153.319 1.00 56.03  ? 296 PHE A CB  1 
ATOM   10480 C  CG  . PHE D 1 349 ? 156.020 116.971 153.074 1.00 60.92  ? 296 PHE A CG  1 
ATOM   10481 C  CD1 . PHE D 1 349 ? 156.237 116.126 152.007 1.00 64.35  ? 296 PHE A CD1 1 
ATOM   10482 C  CD2 . PHE D 1 349 ? 157.077 117.270 153.907 1.00 63.87  ? 296 PHE A CD2 1 
ATOM   10483 C  CE1 . PHE D 1 349 ? 157.482 115.587 151.781 1.00 67.46  ? 296 PHE A CE1 1 
ATOM   10484 C  CE2 . PHE D 1 349 ? 158.325 116.732 153.683 1.00 67.75  ? 296 PHE A CE2 1 
ATOM   10485 C  CZ  . PHE D 1 349 ? 158.528 115.893 152.619 1.00 68.99  ? 296 PHE A CZ  1 
ATOM   10486 N  N   . VAL D 1 350 ? 151.730 117.984 154.389 1.00 59.92  ? 297 VAL A N   1 
ATOM   10487 C  CA  . VAL D 1 350 ? 150.832 118.755 155.246 1.00 57.55  ? 297 VAL A CA  1 
ATOM   10488 C  C   . VAL D 1 350 ? 150.050 117.833 156.179 1.00 64.85  ? 297 VAL A C   1 
ATOM   10489 O  O   . VAL D 1 350 ? 149.952 118.077 157.393 1.00 67.67  ? 297 VAL A O   1 
ATOM   10490 C  CB  . VAL D 1 350 ? 149.902 119.627 154.390 1.00 51.05  ? 297 VAL A CB  1 
ATOM   10491 C  CG1 . VAL D 1 350 ? 148.861 120.279 155.249 1.00 57.39  ? 297 VAL A CG1 1 
ATOM   10492 C  CG2 . VAL D 1 350 ? 150.707 120.678 153.679 1.00 53.46  ? 297 VAL A CG2 1 
ATOM   10493 N  N   . PHE D 1 351 ? 149.492 116.752 155.634 1.00 60.60  ? 298 PHE A N   1 
ATOM   10494 C  CA  . PHE D 1 351 ? 148.765 115.818 156.481 1.00 64.89  ? 298 PHE A CA  1 
ATOM   10495 C  C   . PHE D 1 351 ? 149.693 115.126 157.470 1.00 73.19  ? 298 PHE A C   1 
ATOM   10496 O  O   . PHE D 1 351 ? 149.272 114.795 158.584 1.00 79.73  ? 298 PHE A O   1 
ATOM   10497 C  CB  . PHE D 1 351 ? 148.028 114.792 155.630 1.00 66.55  ? 298 PHE A CB  1 
ATOM   10498 C  CG  . PHE D 1 351 ? 146.557 114.745 155.892 1.00 75.62  ? 298 PHE A CG  1 
ATOM   10499 C  CD1 . PHE D 1 351 ? 146.061 114.095 157.010 1.00 80.75  ? 298 PHE A CD1 1 
ATOM   10500 C  CD2 . PHE D 1 351 ? 145.667 115.351 155.027 1.00 75.34  ? 298 PHE A CD2 1 
ATOM   10501 C  CE1 . PHE D 1 351 ? 144.704 114.053 157.262 1.00 82.91  ? 298 PHE A CE1 1 
ATOM   10502 C  CE2 . PHE D 1 351 ? 144.308 115.312 155.271 1.00 81.96  ? 298 PHE A CE2 1 
ATOM   10503 C  CZ  . PHE D 1 351 ? 143.826 114.661 156.392 1.00 83.03  ? 298 PHE A CZ  1 
ATOM   10504 N  N   . SER D 1 352 ? 150.951 114.902 157.092 1.00 68.38  ? 299 SER A N   1 
ATOM   10505 C  CA  . SER D 1 352 ? 151.915 114.343 158.028 1.00 68.55  ? 299 SER A CA  1 
ATOM   10506 C  C   . SER D 1 352 ? 152.177 115.302 159.178 1.00 73.55  ? 299 SER A C   1 
ATOM   10507 O  O   . SER D 1 352 ? 152.325 114.873 160.325 1.00 76.22  ? 299 SER A O   1 
ATOM   10508 C  CB  . SER D 1 352 ? 153.213 114.007 157.300 1.00 67.00  ? 299 SER A CB  1 
ATOM   10509 O  OG  . SER D 1 352 ? 154.200 113.551 158.203 1.00 74.71  ? 299 SER A OG  1 
ATOM   10510 N  N   . ALA D 1 353 ? 152.245 116.603 158.892 1.00 75.27  ? 300 ALA A N   1 
ATOM   10511 C  CA  . ALA D 1 353 ? 152.381 117.578 159.969 1.00 73.33  ? 300 ALA A CA  1 
ATOM   10512 C  C   . ALA D 1 353 ? 151.190 117.514 160.918 1.00 77.65  ? 300 ALA A C   1 
ATOM   10513 O  O   . ALA D 1 353 ? 151.358 117.516 162.146 1.00 80.62  ? 300 ALA A O   1 
ATOM   10514 C  CB  . ALA D 1 353 ? 152.531 118.983 159.393 1.00 68.11  ? 300 ALA A CB  1 
ATOM   10515 N  N   . LEU D 1 354 ? 149.978 117.440 160.365 1.00 77.70  ? 301 LEU A N   1 
ATOM   10516 C  CA  . LEU D 1 354 ? 148.791 117.363 161.219 1.00 77.36  ? 301 LEU A CA  1 
ATOM   10517 C  C   . LEU D 1 354 ? 148.792 116.095 162.072 1.00 76.91  ? 301 LEU A C   1 
ATOM   10518 O  O   . LEU D 1 354 ? 148.486 116.138 163.273 1.00 78.85  ? 301 LEU A O   1 
ATOM   10519 C  CB  . LEU D 1 354 ? 147.527 117.432 160.367 1.00 76.38  ? 301 LEU A CB  1 
ATOM   10520 C  CG  . LEU D 1 354 ? 146.223 117.675 161.123 1.00 75.65  ? 301 LEU A CG  1 
ATOM   10521 C  CD1 . LEU D 1 354 ? 146.311 118.952 161.933 1.00 74.24  ? 301 LEU A CD1 1 
ATOM   10522 C  CD2 . LEU D 1 354 ? 145.056 117.729 160.157 1.00 71.64  ? 301 LEU A CD2 1 
ATOM   10523 N  N   . ILE D 1 355 ? 149.142 114.956 161.473 1.00 76.79  ? 302 ILE A N   1 
ATOM   10524 C  CA  . ILE D 1 355 ? 149.151 113.696 162.210 1.00 78.88  ? 302 ILE A CA  1 
ATOM   10525 C  C   . ILE D 1 355 ? 150.242 113.698 163.275 1.00 81.68  ? 302 ILE A C   1 
ATOM   10526 O  O   . ILE D 1 355 ? 150.053 113.166 164.377 1.00 82.72  ? 302 ILE A O   1 
ATOM   10527 C  CB  . ILE D 1 355 ? 149.299 112.517 161.232 1.00 80.33  ? 302 ILE A CB  1 
ATOM   10528 C  CG1 . ILE D 1 355 ? 147.965 112.250 160.538 1.00 83.88  ? 302 ILE A CG1 1 
ATOM   10529 C  CG2 . ILE D 1 355 ? 149.790 111.272 161.947 1.00 77.56  ? 302 ILE A CG2 1 
ATOM   10530 C  CD1 . ILE D 1 355 ? 148.035 111.194 159.461 1.00 79.40  ? 302 ILE A CD1 1 
ATOM   10531 N  N   . GLU D 1 356 ? 151.396 114.295 162.973 1.00 83.19  ? 303 GLU A N   1 
ATOM   10532 C  CA  . GLU D 1 356 ? 152.444 114.420 163.978 1.00 80.96  ? 303 GLU A CA  1 
ATOM   10533 C  C   . GLU D 1 356 ? 151.966 115.252 165.153 1.00 86.10  ? 303 GLU A C   1 
ATOM   10534 O  O   . GLU D 1 356 ? 152.253 114.925 166.310 1.00 89.19  ? 303 GLU A O   1 
ATOM   10535 C  CB  . GLU D 1 356 ? 153.698 115.040 163.365 1.00 83.20  ? 303 GLU A CB  1 
ATOM   10536 C  CG  . GLU D 1 356 ? 154.885 115.137 164.313 1.00 87.58  ? 303 GLU A CG  1 
ATOM   10537 C  CD  . GLU D 1 356 ? 154.922 116.433 165.109 1.00 91.99  ? 303 GLU A CD  1 
ATOM   10538 O  OE1 . GLU D 1 356 ? 154.001 117.259 164.969 1.00 89.72  ? 303 GLU A OE1 1 
ATOM   10539 O  OE2 . GLU D 1 356 ? 155.882 116.625 165.880 1.00 96.44  ? 303 GLU A OE2 1 
ATOM   10540 N  N   . PHE D 1 357 ? 151.252 116.344 164.876 1.00 89.28  ? 304 PHE A N   1 
ATOM   10541 C  CA  . PHE D 1 357 ? 150.710 117.140 165.971 1.00 88.12  ? 304 PHE A CA  1 
ATOM   10542 C  C   . PHE D 1 357 ? 149.749 116.325 166.819 1.00 88.42  ? 304 PHE A C   1 
ATOM   10543 O  O   . PHE D 1 357 ? 149.761 116.424 168.050 1.00 90.60  ? 304 PHE A O   1 
ATOM   10544 C  CB  . PHE D 1 357 ? 149.995 118.377 165.449 1.00 85.37  ? 304 PHE A CB  1 
ATOM   10545 C  CG  . PHE D 1 357 ? 149.019 118.945 166.431 1.00 89.60  ? 304 PHE A CG  1 
ATOM   10546 C  CD1 . PHE D 1 357 ? 149.466 119.578 167.579 1.00 89.90  ? 304 PHE A CD1 1 
ATOM   10547 C  CD2 . PHE D 1 357 ? 147.658 118.826 166.225 1.00 90.13  ? 304 PHE A CD2 1 
ATOM   10548 C  CE1 . PHE D 1 357 ? 148.575 120.092 168.494 1.00 88.85  ? 304 PHE A CE1 1 
ATOM   10549 C  CE2 . PHE D 1 357 ? 146.765 119.339 167.137 1.00 91.20  ? 304 PHE A CE2 1 
ATOM   10550 C  CZ  . PHE D 1 357 ? 147.225 119.975 168.273 1.00 92.02  ? 304 PHE A CZ  1 
ATOM   10551 N  N   . ALA D 1 358 ? 148.886 115.538 166.175 1.00 90.50  ? 305 ALA A N   1 
ATOM   10552 C  CA  . ALA D 1 358 ? 147.948 114.716 166.933 1.00 90.91  ? 305 ALA A CA  1 
ATOM   10553 C  C   . ALA D 1 358 ? 148.683 113.725 167.827 1.00 93.38  ? 305 ALA A C   1 
ATOM   10554 O  O   . ALA D 1 358 ? 148.334 113.555 169.003 1.00 96.82  ? 305 ALA A O   1 
ATOM   10555 C  CB  . ALA D 1 358 ? 147.002 113.983 165.984 1.00 83.62  ? 305 ALA A CB  1 
ATOM   10556 N  N   . THR D 1 359 ? 149.713 113.072 167.288 1.00 94.15  ? 306 THR A N   1 
ATOM   10557 C  CA  . THR D 1 359 ? 150.480 112.118 168.082 1.00 96.27  ? 306 THR A CA  1 
ATOM   10558 C  C   . THR D 1 359 ? 151.177 112.805 169.250 1.00 99.27  ? 306 THR A C   1 
ATOM   10559 O  O   . THR D 1 359 ? 151.201 112.275 170.366 1.00 104.63 ? 306 THR A O   1 
ATOM   10560 C  CB  . THR D 1 359 ? 151.499 111.398 167.202 1.00 95.23  ? 306 THR A CB  1 
ATOM   10561 O  OG1 . THR D 1 359 ? 150.816 110.686 166.164 1.00 99.15  ? 306 THR A OG1 1 
ATOM   10562 C  CG2 . THR D 1 359 ? 152.314 110.415 168.026 1.00 90.27  ? 306 THR A CG2 1 
ATOM   10563 N  N   . VAL D 1 360 ? 151.749 113.987 169.014 1.00 96.62  ? 307 VAL A N   1 
ATOM   10564 C  CA  . VAL D 1 360 ? 152.408 114.720 170.092 1.00 95.83  ? 307 VAL A CA  1 
ATOM   10565 C  C   . VAL D 1 360 ? 151.406 115.093 171.172 1.00 100.68 ? 307 VAL A C   1 
ATOM   10566 O  O   . VAL D 1 360 ? 151.682 114.958 172.370 1.00 106.20 ? 307 VAL A O   1 
ATOM   10567 C  CB  . VAL D 1 360 ? 153.126 115.961 169.533 1.00 95.80  ? 307 VAL A CB  1 
ATOM   10568 C  CG1 . VAL D 1 360 ? 153.494 116.913 170.653 1.00 96.12  ? 307 VAL A CG1 1 
ATOM   10569 C  CG2 . VAL D 1 360 ? 154.359 115.542 168.772 1.00 96.65  ? 307 VAL A CG2 1 
ATOM   10570 N  N   . ASN D 1 361 ? 150.225 115.563 170.769 1.00 102.10 ? 308 ASN A N   1 
ATOM   10571 C  CA  . ASN D 1 361 ? 149.189 115.896 171.739 1.00 103.65 ? 308 ASN A CA  1 
ATOM   10572 C  C   . ASN D 1 361 ? 148.733 114.669 172.514 1.00 106.00 ? 308 ASN A C   1 
ATOM   10573 O  O   . ASN D 1 361 ? 148.289 114.791 173.660 1.00 105.13 ? 308 ASN A O   1 
ATOM   10574 C  CB  . ASN D 1 361 ? 148.005 116.553 171.031 1.00 100.90 ? 308 ASN A CB  1 
ATOM   10575 C  CG  . ASN D 1 361 ? 146.820 116.754 171.946 1.00 104.54 ? 308 ASN A CG  1 
ATOM   10576 O  OD1 . ASN D 1 361 ? 145.934 115.907 172.025 1.00 109.10 ? 308 ASN A OD1 1 
ATOM   10577 N  ND2 . ASN D 1 361 ? 146.796 117.879 172.646 1.00 104.67 ? 308 ASN A ND2 1 
ATOM   10578 N  N   . TYR D 1 362 ? 148.838 113.482 171.912 1.00 105.76 ? 309 TYR A N   1 
ATOM   10579 C  CA  . TYR D 1 362 ? 148.430 112.262 172.606 1.00 107.90 ? 309 TYR A CA  1 
ATOM   10580 C  C   . TYR D 1 362 ? 149.289 111.998 173.839 1.00 111.56 ? 309 TYR A C   1 
ATOM   10581 O  O   . TYR D 1 362 ? 148.776 111.569 174.878 1.00 114.82 ? 309 TYR A O   1 
ATOM   10582 C  CB  . TYR D 1 362 ? 148.487 111.073 171.650 1.00 106.64 ? 309 TYR A CB  1 
ATOM   10583 C  CG  . TYR D 1 362 ? 148.203 109.743 172.308 1.00 114.47 ? 309 TYR A CG  1 
ATOM   10584 C  CD1 . TYR D 1 362 ? 146.901 109.330 172.545 1.00 115.43 ? 309 TYR A CD1 1 
ATOM   10585 C  CD2 . TYR D 1 362 ? 149.238 108.895 172.680 1.00 112.71 ? 309 TYR A CD2 1 
ATOM   10586 C  CE1 . TYR D 1 362 ? 146.637 108.114 173.144 1.00 117.26 ? 309 TYR A CE1 1 
ATOM   10587 C  CE2 . TYR D 1 362 ? 148.985 107.678 173.277 1.00 115.15 ? 309 TYR A CE2 1 
ATOM   10588 C  CZ  . TYR D 1 362 ? 147.683 107.292 173.507 1.00 120.02 ? 309 TYR A CZ  1 
ATOM   10589 O  OH  . TYR D 1 362 ? 147.425 106.080 174.100 1.00 120.56 ? 309 TYR A OH  1 
ATOM   10590 N  N   . PHE D 1 363 ? 150.598 112.238 173.745 1.00 111.05 ? 310 PHE A N   1 
ATOM   10591 C  CA  . PHE D 1 363 ? 151.525 111.957 174.833 1.00 112.44 ? 310 PHE A CA  1 
ATOM   10592 C  C   . PHE D 1 363 ? 151.810 113.177 175.704 1.00 115.48 ? 310 PHE A C   1 
ATOM   10593 O  O   . PHE D 1 363 ? 152.801 113.184 176.440 1.00 118.64 ? 310 PHE A O   1 
ATOM   10594 C  CB  . PHE D 1 363 ? 152.841 111.404 174.283 1.00 111.94 ? 310 PHE A CB  1 
ATOM   10595 C  CG  . PHE D 1 363 ? 152.728 110.024 173.709 1.00 113.37 ? 310 PHE A CG  1 
ATOM   10596 C  CD1 . PHE D 1 363 ? 152.613 108.923 174.538 1.00 115.77 ? 310 PHE A CD1 1 
ATOM   10597 C  CD2 . PHE D 1 363 ? 152.747 109.825 172.342 1.00 113.40 ? 310 PHE A CD2 1 
ATOM   10598 C  CE1 . PHE D 1 363 ? 152.509 107.651 174.013 1.00 115.27 ? 310 PHE A CE1 1 
ATOM   10599 C  CE2 . PHE D 1 363 ? 152.646 108.555 171.811 1.00 113.59 ? 310 PHE A CE2 1 
ATOM   10600 C  CZ  . PHE D 1 363 ? 152.525 107.467 172.648 1.00 111.42 ? 310 PHE A CZ  1 
ATOM   10601 N  N   . THR D 1 364 ? 150.969 114.210 175.635 1.00 114.38 ? 311 THR A N   1 
ATOM   10602 C  CA  . THR D 1 364 ? 151.249 115.433 176.381 1.00 115.22 ? 311 THR A CA  1 
ATOM   10603 C  C   . THR D 1 364 ? 151.209 115.193 177.885 1.00 120.86 ? 311 THR A C   1 
ATOM   10604 O  O   . THR D 1 364 ? 152.080 115.672 178.620 1.00 120.20 ? 311 THR A O   1 
ATOM   10605 C  CB  . THR D 1 364 ? 150.257 116.525 175.986 1.00 109.21 ? 311 THR A CB  1 
ATOM   10606 O  OG1 . THR D 1 364 ? 150.396 116.806 174.589 1.00 111.43 ? 311 THR A OG1 1 
ATOM   10607 C  CG2 . THR D 1 364 ? 150.518 117.793 176.775 1.00 105.39 ? 311 THR A CG2 1 
ATOM   10608 N  N   . LYS D 1 365 ? 150.209 114.455 178.363 1.00 121.11 ? 312 LYS A N   1 
ATOM   10609 C  CA  . LYS D 1 365 ? 150.095 114.166 179.787 1.00 119.40 ? 312 LYS A CA  1 
ATOM   10610 C  C   . LYS D 1 365 ? 150.728 112.841 180.176 1.00 119.92 ? 312 LYS A C   1 
ATOM   10611 O  O   . LYS D 1 365 ? 151.284 112.728 181.274 1.00 120.36 ? 312 LYS A O   1 
ATOM   10612 C  CB  . LYS D 1 365 ? 148.626 114.160 180.214 1.00 116.17 ? 312 LYS A CB  1 
ATOM   10613 C  CG  . LYS D 1 365 ? 148.051 115.532 180.497 1.00 114.12 ? 312 LYS A CG  1 
ATOM   10614 C  CD  . LYS D 1 365 ? 146.692 115.413 181.163 1.00 114.19 ? 312 LYS A CD  1 
ATOM   10615 C  CE  . LYS D 1 365 ? 146.230 116.741 181.732 1.00 110.76 ? 312 LYS A CE  1 
ATOM   10616 N  NZ  . LYS D 1 365 ? 144.944 116.601 182.465 1.00 101.33 ? 312 LYS A NZ  1 
ATOM   10617 N  N   . SER D 1 366 ? 150.656 111.836 179.303 1.00 119.20 ? 313 SER A N   1 
ATOM   10618 C  CA  . SER D 1 366 ? 151.167 110.515 179.650 1.00 120.61 ? 313 SER A CA  1 
ATOM   10619 C  C   . SER D 1 366 ? 152.686 110.524 179.761 1.00 121.81 ? 313 SER A C   1 
ATOM   10620 O  O   . SER D 1 366 ? 153.245 110.241 180.826 1.00 120.30 ? 313 SER A O   1 
ATOM   10621 C  CB  . SER D 1 366 ? 150.705 109.491 178.612 1.00 118.06 ? 313 SER A CB  1 
ATOM   10622 O  OG  . SER D 1 366 ? 151.090 108.180 178.983 1.00 119.18 ? 313 SER A OG  1 
ATOM   10623 N  N   . GLN D 1 367 ? 153.372 110.846 178.667 1.00 120.92 ? 385 GLN A N   1 
ATOM   10624 C  CA  . GLN D 1 367 ? 154.832 110.831 178.611 1.00 118.94 ? 385 GLN A CA  1 
ATOM   10625 C  C   . GLN D 1 367 ? 155.312 112.136 177.991 1.00 120.36 ? 385 GLN A C   1 
ATOM   10626 O  O   . GLN D 1 367 ? 155.534 112.212 176.775 1.00 121.74 ? 385 GLN A O   1 
ATOM   10627 C  CB  . GLN D 1 367 ? 155.335 109.625 177.823 1.00 118.76 ? 385 GLN A CB  1 
ATOM   10628 C  CG  . GLN D 1 367 ? 154.737 108.310 178.287 1.00 117.28 ? 385 GLN A CG  1 
ATOM   10629 C  CD  . GLN D 1 367 ? 154.892 107.205 177.268 1.00 121.25 ? 385 GLN A CD  1 
ATOM   10630 O  OE1 . GLN D 1 367 ? 155.820 107.213 176.459 1.00 124.43 ? 385 GLN A OE1 1 
ATOM   10631 N  NE2 . GLN D 1 367 ? 153.975 106.247 177.297 1.00 118.33 ? 385 GLN A NE2 1 
ATOM   10632 N  N   . PRO D 1 368 ? 155.475 113.188 178.795 1.00 121.23 ? 386 PRO A N   1 
ATOM   10633 C  CA  . PRO D 1 368 ? 155.959 114.463 178.241 1.00 122.28 ? 386 PRO A CA  1 
ATOM   10634 C  C   . PRO D 1 368 ? 157.321 114.361 177.579 1.00 122.82 ? 386 PRO A C   1 
ATOM   10635 O  O   . PRO D 1 368 ? 157.594 115.099 176.621 1.00 121.93 ? 386 PRO A O   1 
ATOM   10636 C  CB  . PRO D 1 368 ? 155.993 115.387 179.467 1.00 116.48 ? 386 PRO A CB  1 
ATOM   10637 C  CG  . PRO D 1 368 ? 156.029 114.465 180.643 1.00 119.35 ? 386 PRO A CG  1 
ATOM   10638 C  CD  . PRO D 1 368 ? 155.220 113.273 180.240 1.00 119.32 ? 386 PRO A CD  1 
ATOM   10639 N  N   . ALA D 1 369 ? 158.189 113.471 178.062 1.00 122.27 ? 387 ALA A N   1 
ATOM   10640 C  CA  . ALA D 1 369 ? 159.489 113.291 177.425 1.00 120.49 ? 387 ALA A CA  1 
ATOM   10641 C  C   . ALA D 1 369 ? 159.336 112.809 175.989 1.00 120.72 ? 387 ALA A C   1 
ATOM   10642 O  O   . ALA D 1 369 ? 160.044 113.275 175.089 1.00 117.57 ? 387 ALA A O   1 
ATOM   10643 C  CB  . ALA D 1 369 ? 160.338 112.309 178.230 1.00 115.52 ? 387 ALA A CB  1 
ATOM   10644 N  N   . ARG D 1 370 ? 158.414 111.872 175.757 1.00 121.37 ? 388 ARG A N   1 
ATOM   10645 C  CA  . ARG D 1 370 ? 158.211 111.351 174.410 1.00 117.98 ? 388 ARG A CA  1 
ATOM   10646 C  C   . ARG D 1 370 ? 157.709 112.435 173.466 1.00 114.06 ? 388 ARG A C   1 
ATOM   10647 O  O   . ARG D 1 370 ? 158.187 112.549 172.331 1.00 114.87 ? 388 ARG A O   1 
ATOM   10648 C  CB  . ARG D 1 370 ? 157.236 110.177 174.449 1.00 115.00 ? 388 ARG A CB  1 
ATOM   10649 C  CG  . ARG D 1 370 ? 157.119 109.422 173.142 1.00 114.64 ? 388 ARG A CG  1 
ATOM   10650 C  CD  . ARG D 1 370 ? 156.471 108.068 173.359 1.00 116.41 ? 388 ARG A CD  1 
ATOM   10651 N  NE  . ARG D 1 370 ? 156.503 107.246 172.156 1.00 118.75 ? 388 ARG A NE  1 
ATOM   10652 C  CZ  . ARG D 1 370 ? 156.196 105.957 172.121 1.00 117.70 ? 388 ARG A CZ  1 
ATOM   10653 N  NH1 . ARG D 1 370 ? 155.839 105.302 173.213 1.00 115.12 ? 388 ARG A NH1 1 
ATOM   10654 N  NH2 . ARG D 1 370 ? 156.250 105.309 170.961 1.00 112.56 ? 388 ARG A NH2 1 
ATOM   10655 N  N   . ALA D 1 371 ? 156.749 113.244 173.917 1.00 111.36 ? 389 ALA A N   1 
ATOM   10656 C  CA  . ALA D 1 371 ? 156.243 114.321 173.075 1.00 110.99 ? 389 ALA A CA  1 
ATOM   10657 C  C   . ALA D 1 371 ? 157.329 115.347 172.780 1.00 114.35 ? 389 ALA A C   1 
ATOM   10658 O  O   . ALA D 1 371 ? 157.449 115.829 171.645 1.00 115.34 ? 389 ALA A O   1 
ATOM   10659 C  CB  . ALA D 1 371 ? 155.039 114.986 173.738 1.00 109.34 ? 389 ALA A CB  1 
ATOM   10660 N  N   . ALA D 1 372 ? 158.135 115.690 173.787 1.00 114.71 ? 390 ALA A N   1 
ATOM   10661 C  CA  . ALA D 1 372 ? 159.227 116.631 173.559 1.00 116.08 ? 390 ALA A CA  1 
ATOM   10662 C  C   . ALA D 1 372 ? 160.222 116.083 172.545 1.00 114.59 ? 390 ALA A C   1 
ATOM   10663 O  O   . ALA D 1 372 ? 160.681 116.810 171.653 1.00 114.38 ? 390 ALA A O   1 
ATOM   10664 C  CB  . ALA D 1 372 ? 159.926 116.950 174.880 1.00 116.80 ? 390 ALA A CB  1 
ATOM   10665 N  N   . LYS D 1 373 ? 160.565 114.800 172.665 1.00 114.85 ? 391 LYS A N   1 
ATOM   10666 C  CA  . LYS D 1 373 ? 161.497 114.193 171.724 1.00 115.02 ? 391 LYS A CA  1 
ATOM   10667 C  C   . LYS D 1 373 ? 160.932 114.195 170.310 1.00 114.16 ? 391 LYS A C   1 
ATOM   10668 O  O   . LYS D 1 373 ? 161.650 114.496 169.348 1.00 112.91 ? 391 LYS A O   1 
ATOM   10669 C  CB  . LYS D 1 373 ? 161.833 112.770 172.166 1.00 112.20 ? 391 LYS A CB  1 
ATOM   10670 C  CG  . LYS D 1 373 ? 162.723 112.013 171.198 1.00 113.23 ? 391 LYS A CG  1 
ATOM   10671 C  CD  . LYS D 1 373 ? 162.971 110.590 171.674 1.00 115.33 ? 391 LYS A CD  1 
ATOM   10672 C  CE  . LYS D 1 373 ? 163.745 109.793 170.639 1.00 108.38 ? 391 LYS A CE  1 
ATOM   10673 N  NZ  . LYS D 1 373 ? 164.025 108.408 171.097 1.00 95.18  ? 391 LYS A NZ  1 
ATOM   10674 N  N   . ILE D 1 374 ? 159.648 113.858 170.163 1.00 111.16 ? 392 ILE A N   1 
ATOM   10675 C  CA  . ILE D 1 374 ? 159.044 113.832 168.835 1.00 102.73 ? 392 ILE A CA  1 
ATOM   10676 C  C   . ILE D 1 374 ? 159.052 115.223 168.220 1.00 101.70 ? 392 ILE A C   1 
ATOM   10677 O  O   . ILE D 1 374 ? 159.371 115.392 167.037 1.00 103.56 ? 392 ILE A O   1 
ATOM   10678 C  CB  . ILE D 1 374 ? 157.622 113.249 168.897 1.00 97.09  ? 392 ILE A CB  1 
ATOM   10679 C  CG1 . ILE D 1 374 ? 157.665 111.792 169.351 1.00 101.76 ? 392 ILE A CG1 1 
ATOM   10680 C  CG2 . ILE D 1 374 ? 156.962 113.338 167.542 1.00 90.62  ? 392 ILE A CG2 1 
ATOM   10681 C  CD1 . ILE D 1 374 ? 156.302 111.186 169.574 1.00 105.90 ? 392 ILE A CD1 1 
ATOM   10682 N  N   . ASP D 1 375 ? 158.708 116.243 169.009 1.00 99.79  ? 393 ASP A N   1 
ATOM   10683 C  CA  . ASP D 1 375 ? 158.727 117.606 168.490 1.00 99.00  ? 393 ASP A CA  1 
ATOM   10684 C  C   . ASP D 1 375 ? 160.127 118.008 168.047 1.00 101.90 ? 393 ASP A C   1 
ATOM   10685 O  O   . ASP D 1 375 ? 160.312 118.564 166.956 1.00 103.67 ? 393 ASP A O   1 
ATOM   10686 C  CB  . ASP D 1 375 ? 158.200 118.579 169.541 1.00 102.56 ? 393 ASP A CB  1 
ATOM   10687 C  CG  . ASP D 1 375 ? 156.726 118.861 169.382 1.00 106.15 ? 393 ASP A CG  1 
ATOM   10688 O  OD1 . ASP D 1 375 ? 156.090 118.217 168.524 1.00 106.91 ? 393 ASP A OD1 1 
ATOM   10689 O  OD2 . ASP D 1 375 ? 156.205 119.731 170.106 1.00 107.86 ? 393 ASP A OD2 1 
ATOM   10690 N  N   . ARG D 1 376 ? 161.131 117.729 168.882 1.00 105.59 ? 394 ARG A N   1 
ATOM   10691 C  CA  . ARG D 1 376 ? 162.494 118.132 168.547 1.00 105.86 ? 394 ARG A CA  1 
ATOM   10692 C  C   . ARG D 1 376 ? 162.996 117.414 167.301 1.00 103.18 ? 394 ARG A C   1 
ATOM   10693 O  O   . ARG D 1 376 ? 163.670 118.018 166.460 1.00 98.83  ? 394 ARG A O   1 
ATOM   10694 C  CB  . ARG D 1 376 ? 163.423 117.873 169.731 1.00 111.58 ? 394 ARG A CB  1 
ATOM   10695 C  CG  . ARG D 1 376 ? 163.184 118.806 170.900 1.00 117.91 ? 394 ARG A CG  1 
ATOM   10696 C  CD  . ARG D 1 376 ? 163.983 118.394 172.121 1.00 122.96 ? 394 ARG A CD  1 
ATOM   10697 N  NE  . ARG D 1 376 ? 163.680 119.246 173.264 1.00 129.28 ? 394 ARG A NE  1 
ATOM   10698 C  CZ  . ARG D 1 376 ? 164.167 119.067 174.484 1.00 133.82 ? 394 ARG A CZ  1 
ATOM   10699 N  NH1 . ARG D 1 376 ? 164.987 118.066 174.762 1.00 136.93 ? 394 ARG A NH1 1 
ATOM   10700 N  NH2 . ARG D 1 376 ? 163.824 119.915 175.450 1.00 132.50 ? 394 ARG A NH2 1 
ATOM   10701 N  N   . LEU D 1 377 ? 162.685 116.123 167.167 1.00 102.86 ? 395 LEU A N   1 
ATOM   10702 C  CA  . LEU D 1 377 ? 163.090 115.394 165.970 1.00 98.87  ? 395 LEU A CA  1 
ATOM   10703 C  C   . LEU D 1 377 ? 162.388 115.930 164.729 1.00 97.86  ? 395 LEU A C   1 
ATOM   10704 O  O   . LEU D 1 377 ? 163.029 116.146 163.693 1.00 97.14  ? 395 LEU A O   1 
ATOM   10705 C  CB  . LEU D 1 377 ? 162.811 113.902 166.141 1.00 99.77  ? 395 LEU A CB  1 
ATOM   10706 C  CG  . LEU D 1 377 ? 163.684 113.145 167.141 1.00 100.38 ? 395 LEU A CG  1 
ATOM   10707 C  CD1 . LEU D 1 377 ? 163.220 111.705 167.276 1.00 96.96  ? 395 LEU A CD1 1 
ATOM   10708 C  CD2 . LEU D 1 377 ? 165.141 113.196 166.719 1.00 96.62  ? 395 LEU A CD2 1 
ATOM   10709 N  N   . SER D 1 378 ? 161.076 116.172 164.820 1.00 97.11  ? 396 SER A N   1 
ATOM   10710 C  CA  . SER D 1 378 ? 160.320 116.620 163.655 1.00 89.18  ? 396 SER A CA  1 
ATOM   10711 C  C   . SER D 1 378 ? 160.772 117.995 163.189 1.00 86.41  ? 396 SER A C   1 
ATOM   10712 O  O   . SER D 1 378 ? 160.808 118.258 161.979 1.00 89.72  ? 396 SER A O   1 
ATOM   10713 C  CB  . SER D 1 378 ? 158.825 116.627 163.967 1.00 86.78  ? 396 SER A CB  1 
ATOM   10714 O  OG  . SER D 1 378 ? 158.362 115.320 164.250 1.00 90.08  ? 396 SER A OG  1 
ATOM   10715 N  N   . ARG D 1 379 ? 161.150 118.870 164.128 1.00 86.95  ? 397 ARG A N   1 
ATOM   10716 C  CA  . ARG D 1 379 ? 161.550 120.227 163.765 1.00 92.73  ? 397 ARG A CA  1 
ATOM   10717 C  C   . ARG D 1 379 ? 162.670 120.243 162.735 1.00 95.53  ? 397 ARG A C   1 
ATOM   10718 O  O   . ARG D 1 379 ? 162.770 121.185 161.943 1.00 94.61  ? 397 ARG A O   1 
ATOM   10719 C  CB  . ARG D 1 379 ? 161.993 121.004 165.008 1.00 97.39  ? 397 ARG A CB  1 
ATOM   10720 C  CG  . ARG D 1 379 ? 160.860 121.515 165.876 1.00 96.67  ? 397 ARG A CG  1 
ATOM   10721 C  CD  . ARG D 1 379 ? 161.380 122.225 167.114 1.00 95.94  ? 397 ARG A CD  1 
ATOM   10722 N  NE  . ARG D 1 379 ? 160.295 122.710 167.958 1.00 100.10 ? 397 ARG A NE  1 
ATOM   10723 C  CZ  . ARG D 1 379 ? 160.465 123.326 169.119 1.00 100.81 ? 397 ARG A CZ  1 
ATOM   10724 N  NH1 . ARG D 1 379 ? 161.671 123.547 169.614 1.00 101.97 ? 397 ARG A NH1 1 
ATOM   10725 N  NH2 . ARG D 1 379 ? 159.397 123.733 169.799 1.00 97.42  ? 397 ARG A NH2 1 
ATOM   10726 N  N   . ILE D 1 380 ? 163.524 119.223 162.733 1.00 95.75  ? 398 ILE A N   1 
ATOM   10727 C  CA  . ILE D 1 380 ? 164.644 119.174 161.803 1.00 94.86  ? 398 ILE A CA  1 
ATOM   10728 C  C   . ILE D 1 380 ? 164.344 118.165 160.704 1.00 89.90  ? 398 ILE A C   1 
ATOM   10729 O  O   . ILE D 1 380 ? 164.838 118.296 159.579 1.00 89.78  ? 398 ILE A O   1 
ATOM   10730 C  CB  . ILE D 1 380 ? 165.955 118.838 162.536 1.00 97.64  ? 398 ILE A CB  1 
ATOM   10731 C  CG1 . ILE D 1 380 ? 166.155 119.796 163.709 1.00 98.72  ? 398 ILE A CG1 1 
ATOM   10732 C  CG2 . ILE D 1 380 ? 167.144 118.927 161.592 1.00 96.56  ? 398 ILE A CG2 1 
ATOM   10733 C  CD1 . ILE D 1 380 ? 167.444 119.574 164.465 1.00 100.87 ? 398 ILE A CD1 1 
ATOM   10734 N  N   . ALA D 1 381 ? 163.519 117.162 161.010 1.00 89.21  ? 399 ALA A N   1 
ATOM   10735 C  CA  . ALA D 1 381 ? 163.221 116.134 160.019 1.00 85.52  ? 399 ALA A CA  1 
ATOM   10736 C  C   . ALA D 1 381 ? 162.398 116.692 158.866 1.00 84.88  ? 399 ALA A C   1 
ATOM   10737 O  O   . ALA D 1 381 ? 162.726 116.467 157.696 1.00 83.85  ? 399 ALA A O   1 
ATOM   10738 C  CB  . ALA D 1 381 ? 162.491 114.964 160.676 1.00 82.39  ? 399 ALA A CB  1 
ATOM   10739 N  N   . PHE D 1 382 ? 161.319 117.413 159.170 1.00 84.29  ? 400 PHE A N   1 
ATOM   10740 C  CA  . PHE D 1 382 ? 160.407 117.827 158.104 1.00 75.57  ? 400 PHE A CA  1 
ATOM   10741 C  C   . PHE D 1 382 ? 161.043 118.792 157.108 1.00 78.32  ? 400 PHE A C   1 
ATOM   10742 O  O   . PHE D 1 382 ? 160.938 118.542 155.893 1.00 80.05  ? 400 PHE A O   1 
ATOM   10743 C  CB  . PHE D 1 382 ? 159.125 118.400 158.711 1.00 73.30  ? 400 PHE A CB  1 
ATOM   10744 C  CG  . PHE D 1 382 ? 158.112 117.358 159.072 1.00 78.62  ? 400 PHE A CG  1 
ATOM   10745 C  CD1 . PHE D 1 382 ? 158.340 116.487 160.118 1.00 81.68  ? 400 PHE A CD1 1 
ATOM   10746 C  CD2 . PHE D 1 382 ? 156.928 117.252 158.368 1.00 77.69  ? 400 PHE A CD2 1 
ATOM   10747 C  CE1 . PHE D 1 382 ? 157.409 115.528 160.453 1.00 79.60  ? 400 PHE A CE1 1 
ATOM   10748 C  CE2 . PHE D 1 382 ? 155.994 116.295 158.701 1.00 77.44  ? 400 PHE A CE2 1 
ATOM   10749 C  CZ  . PHE D 1 382 ? 156.235 115.432 159.746 1.00 78.08  ? 400 PHE A CZ  1 
ATOM   10750 N  N   . PRO D 1 383 ? 161.688 119.890 157.519 1.00 78.47  ? 401 PRO A N   1 
ATOM   10751 C  CA  . PRO D 1 383 ? 162.332 120.753 156.513 1.00 78.99  ? 401 PRO A CA  1 
ATOM   10752 C  C   . PRO D 1 383 ? 163.394 120.035 155.703 1.00 79.15  ? 401 PRO A C   1 
ATOM   10753 O  O   . PRO D 1 383 ? 163.517 120.272 154.496 1.00 77.46  ? 401 PRO A O   1 
ATOM   10754 C  CB  . PRO D 1 383 ? 162.928 121.887 157.357 1.00 74.61  ? 401 PRO A CB  1 
ATOM   10755 C  CG  . PRO D 1 383 ? 162.127 121.894 158.599 1.00 78.99  ? 401 PRO A CG  1 
ATOM   10756 C  CD  . PRO D 1 383 ? 161.803 120.463 158.870 1.00 78.32  ? 401 PRO A CD  1 
ATOM   10757 N  N   . LEU D 1 384 ? 164.155 119.143 156.337 1.00 79.32  ? 402 LEU A N   1 
ATOM   10758 C  CA  . LEU D 1 384 ? 165.192 118.406 155.624 1.00 77.86  ? 402 LEU A CA  1 
ATOM   10759 C  C   . LEU D 1 384 ? 164.589 117.520 154.541 1.00 79.23  ? 402 LEU A C   1 
ATOM   10760 O  O   . LEU D 1 384 ? 165.054 117.516 153.395 1.00 80.08  ? 402 LEU A O   1 
ATOM   10761 C  CB  . LEU D 1 384 ? 166.003 117.576 156.617 1.00 79.85  ? 402 LEU A CB  1 
ATOM   10762 C  CG  . LEU D 1 384 ? 167.157 116.726 156.093 1.00 84.70  ? 402 LEU A CG  1 
ATOM   10763 C  CD1 . LEU D 1 384 ? 168.280 117.605 155.564 1.00 80.23  ? 402 LEU A CD1 1 
ATOM   10764 C  CD2 . LEU D 1 384 ? 167.654 115.804 157.191 1.00 84.24  ? 402 LEU A CD2 1 
ATOM   10765 N  N   . LEU D 1 385 ? 163.545 116.764 154.885 1.00 77.53  ? 403 LEU A N   1 
ATOM   10766 C  CA  . LEU D 1 385 ? 162.914 115.893 153.900 1.00 76.90  ? 403 LEU A CA  1 
ATOM   10767 C  C   . LEU D 1 385 ? 162.278 116.694 152.774 1.00 76.48  ? 403 LEU A C   1 
ATOM   10768 O  O   . LEU D 1 385 ? 162.382 116.316 151.602 1.00 77.32  ? 403 LEU A O   1 
ATOM   10769 C  CB  . LEU D 1 385 ? 161.871 115.002 154.568 1.00 78.38  ? 403 LEU A CB  1 
ATOM   10770 C  CG  . LEU D 1 385 ? 162.358 113.639 155.052 1.00 82.07  ? 403 LEU A CG  1 
ATOM   10771 C  CD1 . LEU D 1 385 ? 161.181 112.786 155.479 1.00 79.12  ? 403 LEU A CD1 1 
ATOM   10772 C  CD2 . LEU D 1 385 ? 163.168 112.940 153.971 1.00 80.88  ? 403 LEU A CD2 1 
ATOM   10773 N  N   . PHE D 1 386 ? 161.608 117.800 153.105 1.00 73.60  ? 404 PHE A N   1 
ATOM   10774 C  CA  . PHE D 1 386 ? 160.993 118.608 152.058 1.00 67.44  ? 404 PHE A CA  1 
ATOM   10775 C  C   . PHE D 1 386 ? 162.047 119.192 151.127 1.00 71.84  ? 404 PHE A C   1 
ATOM   10776 O  O   . PHE D 1 386 ? 161.854 119.228 149.907 1.00 72.39  ? 404 PHE A O   1 
ATOM   10777 C  CB  . PHE D 1 386 ? 160.140 119.713 152.671 1.00 65.83  ? 404 PHE A CB  1 
ATOM   10778 C  CG  . PHE D 1 386 ? 159.281 120.436 151.677 1.00 63.43  ? 404 PHE A CG  1 
ATOM   10779 C  CD1 . PHE D 1 386 ? 158.362 119.750 150.909 1.00 64.59  ? 404 PHE A CD1 1 
ATOM   10780 C  CD2 . PHE D 1 386 ? 159.380 121.805 151.526 1.00 58.94  ? 404 PHE A CD2 1 
ATOM   10781 C  CE1 . PHE D 1 386 ? 157.567 120.413 149.999 1.00 61.84  ? 404 PHE A CE1 1 
ATOM   10782 C  CE2 . PHE D 1 386 ? 158.588 122.470 150.619 1.00 58.77  ? 404 PHE A CE2 1 
ATOM   10783 C  CZ  . PHE D 1 386 ? 157.680 121.773 149.855 1.00 56.90  ? 404 PHE A CZ  1 
ATOM   10784 N  N   . GLY D 1 387 ? 163.173 119.648 151.679 1.00 71.68  ? 405 GLY A N   1 
ATOM   10785 C  CA  . GLY D 1 387 ? 164.239 120.162 150.837 1.00 69.52  ? 405 GLY A CA  1 
ATOM   10786 C  C   . GLY D 1 387 ? 164.845 119.097 149.945 1.00 71.95  ? 405 GLY A C   1 
ATOM   10787 O  O   . GLY D 1 387 ? 165.134 119.347 148.772 1.00 74.26  ? 405 GLY A O   1 
ATOM   10788 N  N   . ILE D 1 388 ? 165.043 117.895 150.485 1.00 71.78  ? 406 ILE A N   1 
ATOM   10789 C  CA  . ILE D 1 388 ? 165.576 116.801 149.676 1.00 70.02  ? 406 ILE A CA  1 
ATOM   10790 C  C   . ILE D 1 388 ? 164.620 116.476 148.537 1.00 72.33  ? 406 ILE A C   1 
ATOM   10791 O  O   . ILE D 1 388 ? 165.031 116.315 147.380 1.00 75.44  ? 406 ILE A O   1 
ATOM   10792 C  CB  . ILE D 1 388 ? 165.848 115.567 150.552 1.00 72.11  ? 406 ILE A CB  1 
ATOM   10793 C  CG1 . ILE D 1 388 ? 167.002 115.839 151.514 1.00 76.70  ? 406 ILE A CG1 1 
ATOM   10794 C  CG2 . ILE D 1 388 ? 166.148 114.356 149.691 1.00 69.47  ? 406 ILE A CG2 1 
ATOM   10795 C  CD1 . ILE D 1 388 ? 167.314 114.675 152.426 1.00 82.65  ? 406 ILE A CD1 1 
ATOM   10796 N  N   . PHE D 1 389 ? 163.324 116.382 148.847 1.00 70.19  ? 407 PHE A N   1 
ATOM   10797 C  CA  . PHE D 1 389 ? 162.348 116.096 147.804 1.00 66.59  ? 407 PHE A CA  1 
ATOM   10798 C  C   . PHE D 1 389 ? 162.336 117.186 146.749 1.00 65.53  ? 407 PHE A C   1 
ATOM   10799 O  O   . PHE D 1 389 ? 162.250 116.892 145.555 1.00 67.17  ? 407 PHE A O   1 
ATOM   10800 C  CB  . PHE D 1 389 ? 160.948 115.942 148.388 1.00 67.52  ? 407 PHE A CB  1 
ATOM   10801 C  CG  . PHE D 1 389 ? 159.859 116.244 147.399 1.00 67.43  ? 407 PHE A CG  1 
ATOM   10802 C  CD1 . PHE D 1 389 ? 159.492 115.310 146.451 1.00 61.38  ? 407 PHE A CD1 1 
ATOM   10803 C  CD2 . PHE D 1 389 ? 159.213 117.470 147.407 1.00 65.86  ? 407 PHE A CD2 1 
ATOM   10804 C  CE1 . PHE D 1 389 ? 158.501 115.585 145.539 1.00 59.62  ? 407 PHE A CE1 1 
ATOM   10805 C  CE2 . PHE D 1 389 ? 158.224 117.750 146.495 1.00 61.12  ? 407 PHE A CE2 1 
ATOM   10806 C  CZ  . PHE D 1 389 ? 157.867 116.807 145.561 1.00 60.63  ? 407 PHE A CZ  1 
ATOM   10807 N  N   . ASN D 1 390 ? 162.382 118.450 147.166 1.00 63.86  ? 408 ASN A N   1 
ATOM   10808 C  CA  . ASN D 1 390 ? 162.349 119.533 146.193 1.00 63.64  ? 408 ASN A CA  1 
ATOM   10809 C  C   . ASN D 1 390 ? 163.573 119.495 145.295 1.00 64.43  ? 408 ASN A C   1 
ATOM   10810 O  O   . ASN D 1 390 ? 163.468 119.685 144.077 1.00 66.10  ? 408 ASN A O   1 
ATOM   10811 C  CB  . ASN D 1 390 ? 162.237 120.878 146.901 1.00 64.78  ? 408 ASN A CB  1 
ATOM   10812 C  CG  . ASN D 1 390 ? 160.879 121.512 146.714 1.00 66.02  ? 408 ASN A CG  1 
ATOM   10813 O  OD1 . ASN D 1 390 ? 160.686 122.337 145.827 1.00 66.02  ? 408 ASN A OD1 1 
ATOM   10814 N  ND2 . ASN D 1 390 ? 159.925 121.121 147.544 1.00 67.69  ? 408 ASN A ND2 1 
ATOM   10815 N  N   . LEU D 1 391 ? 164.743 119.235 145.875 1.00 65.40  ? 409 LEU A N   1 
ATOM   10816 C  CA  . LEU D 1 391 ? 165.953 119.147 145.071 1.00 67.83  ? 409 LEU A CA  1 
ATOM   10817 C  C   . LEU D 1 391 ? 165.845 118.022 144.052 1.00 67.49  ? 409 LEU A C   1 
ATOM   10818 O  O   . LEU D 1 391 ? 166.147 118.212 142.869 1.00 69.68  ? 409 LEU A O   1 
ATOM   10819 C  CB  . LEU D 1 391 ? 167.166 118.947 145.974 1.00 70.79  ? 409 LEU A CB  1 
ATOM   10820 C  CG  . LEU D 1 391 ? 168.504 119.378 145.382 1.00 74.12  ? 409 LEU A CG  1 
ATOM   10821 C  CD1 . LEU D 1 391 ? 168.458 120.852 145.029 1.00 67.78  ? 409 LEU A CD1 1 
ATOM   10822 C  CD2 . LEU D 1 391 ? 169.630 119.092 146.356 1.00 72.35  ? 409 LEU A CD2 1 
ATOM   10823 N  N   . VAL D 1 392 ? 165.380 116.848 144.486 1.00 64.20  ? 410 VAL A N   1 
ATOM   10824 C  CA  . VAL D 1 392 ? 165.265 115.716 143.569 1.00 63.26  ? 410 VAL A CA  1 
ATOM   10825 C  C   . VAL D 1 392 ? 164.236 116.000 142.480 1.00 66.59  ? 410 VAL A C   1 
ATOM   10826 O  O   . VAL D 1 392 ? 164.473 115.724 141.299 1.00 68.60  ? 410 VAL A O   1 
ATOM   10827 C  CB  . VAL D 1 392 ? 164.933 114.429 144.341 1.00 63.21  ? 410 VAL A CB  1 
ATOM   10828 C  CG1 . VAL D 1 392 ? 164.666 113.298 143.374 1.00 62.68  ? 410 VAL A CG1 1 
ATOM   10829 C  CG2 . VAL D 1 392 ? 166.077 114.071 145.255 1.00 69.16  ? 410 VAL A CG2 1 
ATOM   10830 N  N   . TYR D 1 393 ? 163.085 116.563 142.853 1.00 64.86  ? 411 TYR A N   1 
ATOM   10831 C  CA  . TYR D 1 393 ? 162.025 116.837 141.887 1.00 58.06  ? 411 TYR A CA  1 
ATOM   10832 C  C   . TYR D 1 393 ? 162.484 117.827 140.826 1.00 59.60  ? 411 TYR A C   1 
ATOM   10833 O  O   . TYR D 1 393 ? 162.329 117.583 139.622 1.00 61.88  ? 411 TYR A O   1 
ATOM   10834 C  CB  . TYR D 1 393 ? 160.792 117.368 142.619 1.00 54.30  ? 411 TYR A CB  1 
ATOM   10835 C  CG  . TYR D 1 393 ? 159.630 117.768 141.739 1.00 53.11  ? 411 TYR A CG  1 
ATOM   10836 C  CD1 . TYR D 1 393 ? 158.654 116.853 141.394 1.00 52.84  ? 411 TYR A CD1 1 
ATOM   10837 C  CD2 . TYR D 1 393 ? 159.497 119.068 141.280 1.00 54.40  ? 411 TYR A CD2 1 
ATOM   10838 C  CE1 . TYR D 1 393 ? 157.586 117.214 140.606 1.00 52.18  ? 411 TYR A CE1 1 
ATOM   10839 C  CE2 . TYR D 1 393 ? 158.435 119.437 140.487 1.00 51.87  ? 411 TYR A CE2 1 
ATOM   10840 C  CZ  . TYR D 1 393 ? 157.483 118.506 140.154 1.00 51.99  ? 411 TYR A CZ  1 
ATOM   10841 O  OH  . TYR D 1 393 ? 156.418 118.866 139.369 1.00 56.50  ? 411 TYR A OH  1 
ATOM   10842 N  N   . TRP D 1 394 ? 163.055 118.954 141.250 1.00 56.80  ? 412 TRP A N   1 
ATOM   10843 C  CA  . TRP D 1 394 ? 163.458 119.956 140.273 1.00 58.56  ? 412 TRP A CA  1 
ATOM   10844 C  C   . TRP D 1 394 ? 164.670 119.508 139.471 1.00 64.72  ? 412 TRP A C   1 
ATOM   10845 O  O   . TRP D 1 394 ? 164.780 119.850 138.291 1.00 66.95  ? 412 TRP A O   1 
ATOM   10846 C  CB  . TRP D 1 394 ? 163.719 121.291 140.961 1.00 59.08  ? 412 TRP A CB  1 
ATOM   10847 C  CG  . TRP D 1 394 ? 162.469 121.907 141.508 1.00 59.15  ? 412 TRP A CG  1 
ATOM   10848 C  CD1 . TRP D 1 394 ? 162.132 122.049 142.816 1.00 59.90  ? 412 TRP A CD1 1 
ATOM   10849 C  CD2 . TRP D 1 394 ? 161.382 122.449 140.754 1.00 58.45  ? 412 TRP A CD2 1 
ATOM   10850 N  NE1 . TRP D 1 394 ? 160.906 122.652 142.928 1.00 59.00  ? 412 TRP A NE1 1 
ATOM   10851 C  CE2 . TRP D 1 394 ? 160.424 122.905 141.673 1.00 56.31  ? 412 TRP A CE2 1 
ATOM   10852 C  CE3 . TRP D 1 394 ? 161.126 122.591 139.390 1.00 57.84  ? 412 TRP A CE3 1 
ATOM   10853 C  CZ2 . TRP D 1 394 ? 159.236 123.497 141.274 1.00 53.56  ? 412 TRP A CZ2 1 
ATOM   10854 C  CZ3 . TRP D 1 394 ? 159.949 123.175 138.998 1.00 56.01  ? 412 TRP A CZ3 1 
ATOM   10855 C  CH2 . TRP D 1 394 ? 159.017 123.622 139.934 1.00 53.86  ? 412 TRP A CH2 1 
ATOM   10856 N  N   . ALA D 1 395 ? 165.577 118.732 140.067 1.00 64.61  ? 413 ALA A N   1 
ATOM   10857 C  CA  . ALA D 1 395 ? 166.700 118.216 139.298 1.00 63.53  ? 413 ALA A CA  1 
ATOM   10858 C  C   . ALA D 1 395 ? 166.255 117.170 138.288 1.00 66.25  ? 413 ALA A C   1 
ATOM   10859 O  O   . ALA D 1 395 ? 166.880 117.027 137.234 1.00 75.87  ? 413 ALA A O   1 
ATOM   10860 C  CB  . ALA D 1 395 ? 167.754 117.634 140.236 1.00 63.15  ? 413 ALA A CB  1 
ATOM   10861 N  N   . THR D 1 396 ? 165.195 116.423 138.594 1.00 63.24  ? 414 THR A N   1 
ATOM   10862 C  CA  . THR D 1 396 ? 164.690 115.439 137.645 1.00 65.37  ? 414 THR A CA  1 
ATOM   10863 C  C   . THR D 1 396 ? 163.932 116.100 136.501 1.00 70.24  ? 414 THR A C   1 
ATOM   10864 O  O   . THR D 1 396 ? 164.085 115.705 135.340 1.00 73.42  ? 414 THR A O   1 
ATOM   10865 C  CB  . THR D 1 396 ? 163.802 114.430 138.371 1.00 63.08  ? 414 THR A CB  1 
ATOM   10866 O  OG1 . THR D 1 396 ? 164.620 113.404 138.944 1.00 73.59  ? 414 THR A OG1 1 
ATOM   10867 C  CG2 . THR D 1 396 ? 162.791 113.806 137.424 1.00 58.90  ? 414 THR A CG2 1 
ATOM   10868 N  N   . TYR D 1 397 ? 163.118 117.114 136.798 1.00 70.96  ? 415 TYR A N   1 
ATOM   10869 C  CA  . TYR D 1 397 ? 162.218 117.641 135.781 1.00 65.71  ? 415 TYR A CA  1 
ATOM   10870 C  C   . TYR D 1 397 ? 162.729 118.879 135.058 1.00 70.50  ? 415 TYR A C   1 
ATOM   10871 O  O   . TYR D 1 397 ? 162.255 119.156 133.954 1.00 76.06  ? 415 TYR A O   1 
ATOM   10872 C  CB  . TYR D 1 397 ? 160.848 117.943 136.391 1.00 57.77  ? 415 TYR A CB  1 
ATOM   10873 C  CG  . TYR D 1 397 ? 159.951 116.736 136.423 1.00 59.71  ? 415 TYR A CG  1 
ATOM   10874 C  CD1 . TYR D 1 397 ? 159.556 116.123 135.249 1.00 64.53  ? 415 TYR A CD1 1 
ATOM   10875 C  CD2 . TYR D 1 397 ? 159.506 116.204 137.621 1.00 59.19  ? 415 TYR A CD2 1 
ATOM   10876 C  CE1 . TYR D 1 397 ? 158.740 115.019 135.263 1.00 65.16  ? 415 TYR A CE1 1 
ATOM   10877 C  CE2 . TYR D 1 397 ? 158.691 115.095 137.645 1.00 60.50  ? 415 TYR A CE2 1 
ATOM   10878 C  CZ  . TYR D 1 397 ? 158.309 114.507 136.462 1.00 63.46  ? 415 TYR A CZ  1 
ATOM   10879 O  OH  . TYR D 1 397 ? 157.490 113.402 136.470 1.00 60.53  ? 415 TYR A OH  1 
ATOM   10880 N  N   . LEU D 1 398 ? 163.670 119.630 135.625 1.00 71.36  ? 416 LEU A N   1 
ATOM   10881 C  CA  . LEU D 1 398 ? 164.225 120.787 134.938 1.00 73.81  ? 416 LEU A CA  1 
ATOM   10882 C  C   . LEU D 1 398 ? 165.514 120.475 134.194 1.00 82.23  ? 416 LEU A C   1 
ATOM   10883 O  O   . LEU D 1 398 ? 166.076 121.367 133.553 1.00 81.62  ? 416 LEU A O   1 
ATOM   10884 C  CB  . LEU D 1 398 ? 164.471 121.930 135.926 1.00 65.87  ? 416 LEU A CB  1 
ATOM   10885 C  CG  . LEU D 1 398 ? 163.257 122.758 136.341 1.00 59.52  ? 416 LEU A CG  1 
ATOM   10886 C  CD1 . LEU D 1 398 ? 163.680 123.970 137.135 1.00 54.75  ? 416 LEU A CD1 1 
ATOM   10887 C  CD2 . LEU D 1 398 ? 162.469 123.185 135.125 1.00 61.91  ? 416 LEU A CD2 1 
ATOM   10888 N  N   . ASN D 1 399 ? 166.000 119.235 134.267 1.00 88.59  ? 417 ASN A N   1 
ATOM   10889 C  CA  . ASN D 1 399 ? 167.237 118.848 133.608 1.00 97.28  ? 417 ASN A CA  1 
ATOM   10890 C  C   . ASN D 1 399 ? 167.026 117.925 132.421 1.00 104.69 ? 417 ASN A C   1 
ATOM   10891 O  O   . ASN D 1 399 ? 167.900 117.852 131.553 1.00 108.57 ? 417 ASN A O   1 
ATOM   10892 C  CB  . ASN D 1 399 ? 168.182 118.167 134.608 1.00 92.72  ? 417 ASN A CB  1 
ATOM   10893 C  CG  . ASN D 1 399 ? 169.578 117.979 134.058 1.00 99.27  ? 417 ASN A CG  1 
ATOM   10894 O  OD1 . ASN D 1 399 ? 170.395 118.897 134.087 1.00 105.13 ? 417 ASN A OD1 1 
ATOM   10895 N  ND2 . ASN D 1 399 ? 169.859 116.784 133.554 1.00 98.44  ? 417 ASN A ND2 1 
ATOM   10896 N  N   . ARG D 1 400 ? 165.896 117.232 132.359 1.00 101.84 ? 418 ARG A N   1 
ATOM   10897 C  CA  . ARG D 1 400 ? 165.559 116.400 131.214 1.00 103.26 ? 418 ARG A CA  1 
ATOM   10898 C  C   . ARG D 1 400 ? 164.986 117.248 130.088 1.00 99.95  ? 418 ARG A C   1 
ATOM   10899 O  O   . ARG D 1 400 ? 165.159 118.466 130.068 1.00 98.35  ? 418 ARG A O   1 
ATOM   10900 C  CB  . ARG D 1 400 ? 164.565 115.313 131.619 1.00 97.49  ? 418 ARG A CB  1 
ATOM   10901 C  CG  . ARG D 1 400 ? 163.662 114.850 130.497 1.00 93.91  ? 418 ARG A CG  1 
ATOM   10902 C  CD  . ARG D 1 400 ? 162.870 113.622 130.904 1.00 93.82  ? 418 ARG A CD  1 
ATOM   10903 N  NE  . ARG D 1 400 ? 162.277 113.754 132.228 1.00 92.89  ? 418 ARG A NE  1 
ATOM   10904 C  CZ  . ARG D 1 400 ? 161.560 112.810 132.823 1.00 92.16  ? 418 ARG A CZ  1 
ATOM   10905 N  NH1 . ARG D 1 400 ? 161.309 111.655 132.229 1.00 94.94  ? 418 ARG A NH1 1 
ATOM   10906 N  NH2 . ARG D 1 400 ? 161.086 113.028 134.044 1.00 84.36  ? 418 ARG A NH2 1 
ATOM   10907 N  N   . ASN E 2 62  ? 99.613  125.377 74.827  1.00 99.12  ? 8   ASN C N   1 
ATOM   10908 C  CA  . ASN E 2 62  ? 100.665 124.838 73.974  1.00 103.91 ? 8   ASN C CA  1 
ATOM   10909 C  C   . ASN E 2 62  ? 102.033 125.321 74.438  1.00 101.57 ? 8   ASN C C   1 
ATOM   10910 O  O   . ASN E 2 62  ? 102.354 126.500 74.319  1.00 96.95  ? 8   ASN C O   1 
ATOM   10911 C  CB  . ASN E 2 62  ? 100.434 125.236 72.516  1.00 101.64 ? 8   ASN C CB  1 
ATOM   10912 C  CG  . ASN E 2 62  ? 101.439 124.607 71.576  1.00 103.43 ? 8   ASN C CG  1 
ATOM   10913 O  OD1 . ASN E 2 62  ? 101.997 123.550 71.864  1.00 102.41 ? 8   ASN C OD1 1 
ATOM   10914 N  ND2 . ASN E 2 62  ? 101.675 125.255 70.442  1.00 98.40  ? 8   ASN C ND2 1 
ATOM   10915 N  N   . MET E 2 63  ? 102.841 124.397 74.964  1.00 96.43  ? 9   MET C N   1 
ATOM   10916 C  CA  . MET E 2 63  ? 104.144 124.770 75.496  1.00 89.91  ? 9   MET C CA  1 
ATOM   10917 C  C   . MET E 2 63  ? 105.133 125.170 74.410  1.00 93.28  ? 9   MET C C   1 
ATOM   10918 O  O   . MET E 2 63  ? 106.121 125.843 74.714  1.00 89.36  ? 9   MET C O   1 
ATOM   10919 C  CB  . MET E 2 63  ? 104.725 123.626 76.328  1.00 86.90  ? 9   MET C CB  1 
ATOM   10920 C  CG  . MET E 2 63  ? 104.446 123.745 77.816  1.00 86.36  ? 9   MET C CG  1 
ATOM   10921 S  SD  . MET E 2 63  ? 105.401 122.581 78.803  1.00 97.16  ? 9   MET C SD  1 
ATOM   10922 C  CE  . MET E 2 63  ? 104.842 121.031 78.115  1.00 81.55  ? 9   MET C CE  1 
ATOM   10923 N  N   . SER E 2 64  ? 104.906 124.765 73.160  1.00 96.26  ? 10  SER C N   1 
ATOM   10924 C  CA  . SER E 2 64  ? 105.816 125.170 72.095  1.00 94.33  ? 10  SER C CA  1 
ATOM   10925 C  C   . SER E 2 64  ? 105.767 126.676 71.872  1.00 93.11  ? 10  SER C C   1 
ATOM   10926 O  O   . SER E 2 64  ? 106.809 127.321 71.710  1.00 88.69  ? 10  SER C O   1 
ATOM   10927 C  CB  . SER E 2 64  ? 105.483 124.422 70.806  1.00 94.19  ? 10  SER C CB  1 
ATOM   10928 O  OG  . SER E 2 64  ? 106.478 124.642 69.824  1.00 92.90  ? 10  SER C OG  1 
ATOM   10929 N  N   . PHE E 2 65  ? 104.564 127.252 71.870  1.00 92.66  ? 11  PHE C N   1 
ATOM   10930 C  CA  . PHE E 2 65  ? 104.432 128.694 71.699  1.00 86.48  ? 11  PHE C CA  1 
ATOM   10931 C  C   . PHE E 2 65  ? 105.051 129.448 72.868  1.00 81.57  ? 11  PHE C C   1 
ATOM   10932 O  O   . PHE E 2 65  ? 105.705 130.480 72.675  1.00 79.04  ? 11  PHE C O   1 
ATOM   10933 C  CB  . PHE E 2 65  ? 102.958 129.061 71.537  1.00 83.16  ? 11  PHE C CB  1 
ATOM   10934 C  CG  . PHE E 2 65  ? 102.724 130.506 71.233  1.00 81.68  ? 11  PHE C CG  1 
ATOM   10935 C  CD1 . PHE E 2 65  ? 103.128 131.045 70.029  1.00 79.08  ? 11  PHE C CD1 1 
ATOM   10936 C  CD2 . PHE E 2 65  ? 102.086 131.322 72.144  1.00 85.39  ? 11  PHE C CD2 1 
ATOM   10937 C  CE1 . PHE E 2 65  ? 102.912 132.374 69.745  1.00 77.87  ? 11  PHE C CE1 1 
ATOM   10938 C  CE2 . PHE E 2 65  ? 101.866 132.651 71.865  1.00 87.15  ? 11  PHE C CE2 1 
ATOM   10939 C  CZ  . PHE E 2 65  ? 102.281 133.179 70.663  1.00 83.68  ? 11  PHE C CZ  1 
ATOM   10940 N  N   . VAL E 2 66  ? 104.851 128.952 74.089  1.00 80.07  ? 12  VAL C N   1 
ATOM   10941 C  CA  . VAL E 2 66  ? 105.443 129.590 75.259  1.00 73.97  ? 12  VAL C CA  1 
ATOM   10942 C  C   . VAL E 2 66  ? 106.961 129.515 75.194  1.00 75.30  ? 12  VAL C C   1 
ATOM   10943 O  O   . VAL E 2 66  ? 107.661 130.468 75.553  1.00 76.16  ? 12  VAL C O   1 
ATOM   10944 C  CB  . VAL E 2 66  ? 104.902 128.952 76.550  1.00 71.36  ? 12  VAL C CB  1 
ATOM   10945 C  CG1 . VAL E 2 66  ? 105.428 129.691 77.763  1.00 68.68  ? 12  VAL C CG1 1 
ATOM   10946 C  CG2 . VAL E 2 66  ? 103.393 128.954 76.540  1.00 78.49  ? 12  VAL C CG2 1 
ATOM   10947 N  N   . LYS E 2 67  ? 107.495 128.379 74.746  1.00 74.93  ? 13  LYS C N   1 
ATOM   10948 C  CA  . LYS E 2 67  ? 108.940 128.254 74.608  1.00 75.91  ? 13  LYS C CA  1 
ATOM   10949 C  C   . LYS E 2 67  ? 109.475 129.224 73.564  1.00 77.36  ? 13  LYS C C   1 
ATOM   10950 O  O   . LYS E 2 67  ? 110.518 129.855 73.772  1.00 77.70  ? 13  LYS C O   1 
ATOM   10951 C  CB  . LYS E 2 67  ? 109.312 126.816 74.256  1.00 76.11  ? 13  LYS C CB  1 
ATOM   10952 C  CG  . LYS E 2 67  ? 110.796 126.598 74.053  1.00 74.42  ? 13  LYS C CG  1 
ATOM   10953 C  CD  . LYS E 2 67  ? 111.090 125.172 73.641  1.00 73.10  ? 13  LYS C CD  1 
ATOM   10954 C  CE  . LYS E 2 67  ? 112.521 125.022 73.156  1.00 76.15  ? 13  LYS C CE  1 
ATOM   10955 N  NZ  . LYS E 2 67  ? 113.503 125.426 74.192  1.00 74.52  ? 13  LYS C NZ  1 
ATOM   10956 N  N   . GLU E 2 68  ? 108.769 129.364 72.440  1.00 79.47  ? 14  GLU C N   1 
ATOM   10957 C  CA  . GLU E 2 68  ? 109.184 130.331 71.428  1.00 77.86  ? 14  GLU C CA  1 
ATOM   10958 C  C   . GLU E 2 68  ? 109.183 131.744 71.990  1.00 72.19  ? 14  GLU C C   1 
ATOM   10959 O  O   . GLU E 2 68  ? 110.129 132.508 71.773  1.00 76.49  ? 14  GLU C O   1 
ATOM   10960 C  CB  . GLU E 2 68  ? 108.267 130.252 70.209  1.00 85.43  ? 14  GLU C CB  1 
ATOM   10961 C  CG  . GLU E 2 68  ? 108.342 128.955 69.438  1.00 93.85  ? 14  GLU C CG  1 
ATOM   10962 C  CD  . GLU E 2 68  ? 107.295 128.881 68.348  1.00 102.92 ? 14  GLU C CD  1 
ATOM   10963 O  OE1 . GLU E 2 68  ? 106.870 129.951 67.866  1.00 103.44 ? 14  GLU C OE1 1 
ATOM   10964 O  OE2 . GLU E 2 68  ? 106.886 127.757 67.983  1.00 101.63 ? 14  GLU C OE2 1 
ATOM   10965 N  N   . THR E 2 69  ? 108.135 132.100 72.733  1.00 70.57  ? 15  THR C N   1 
ATOM   10966 C  CA  . THR E 2 69  ? 108.050 133.434 73.314  1.00 66.71  ? 15  THR C CA  1 
ATOM   10967 C  C   . THR E 2 69  ? 109.193 133.688 74.289  1.00 67.92  ? 15  THR C C   1 
ATOM   10968 O  O   . THR E 2 69  ? 109.856 134.731 74.233  1.00 72.42  ? 15  THR C O   1 
ATOM   10969 C  CB  . THR E 2 69  ? 106.706 133.602 74.017  1.00 68.53  ? 15  THR C CB  1 
ATOM   10970 O  OG1 . THR E 2 69  ? 105.649 133.278 73.109  1.00 75.76  ? 15  THR C OG1 1 
ATOM   10971 C  CG2 . THR E 2 69  ? 106.535 135.022 74.494  1.00 63.65  ? 15  THR C CG2 1 
ATOM   10972 N  N   . VAL E 2 70  ? 109.450 132.733 75.183  1.00 65.74  ? 16  VAL C N   1 
ATOM   10973 C  CA  . VAL E 2 70  ? 110.485 132.926 76.193  1.00 67.00  ? 16  VAL C CA  1 
ATOM   10974 C  C   . VAL E 2 70  ? 111.863 132.998 75.548  1.00 70.61  ? 16  VAL C C   1 
ATOM   10975 O  O   . VAL E 2 70  ? 112.700 133.819 75.939  1.00 68.73  ? 16  VAL C O   1 
ATOM   10976 C  CB  . VAL E 2 70  ? 110.406 131.820 77.259  1.00 62.47  ? 16  VAL C CB  1 
ATOM   10977 C  CG1 . VAL E 2 70  ? 111.567 131.937 78.222  1.00 59.96  ? 16  VAL C CG1 1 
ATOM   10978 C  CG2 . VAL E 2 70  ? 109.094 131.917 78.009  1.00 55.90  ? 16  VAL C CG2 1 
ATOM   10979 N  N   . ASP E 2 71  ? 112.125 132.154 74.549  1.00 71.76  ? 17  ASP C N   1 
ATOM   10980 C  CA  . ASP E 2 71  ? 113.407 132.221 73.857  1.00 71.75  ? 17  ASP C CA  1 
ATOM   10981 C  C   . ASP E 2 71  ? 113.570 133.546 73.131  1.00 73.85  ? 17  ASP C C   1 
ATOM   10982 O  O   . ASP E 2 71  ? 114.671 134.105 73.086  1.00 75.26  ? 17  ASP C O   1 
ATOM   10983 C  CB  . ASP E 2 71  ? 113.543 131.055 72.882  1.00 75.87  ? 17  ASP C CB  1 
ATOM   10984 C  CG  . ASP E 2 71  ? 113.786 129.739 73.584  1.00 83.77  ? 17  ASP C CG  1 
ATOM   10985 O  OD1 . ASP E 2 71  ? 114.216 129.766 74.754  1.00 86.51  ? 17  ASP C OD1 1 
ATOM   10986 O  OD2 . ASP E 2 71  ? 113.555 128.678 72.968  1.00 85.30  ? 17  ASP C OD2 1 
ATOM   10987 N  N   . LYS E 2 72  ? 112.484 134.065 72.554  1.00 73.61  ? 18  LYS C N   1 
ATOM   10988 C  CA  . LYS E 2 72  ? 112.546 135.367 71.902  1.00 69.90  ? 18  LYS C CA  1 
ATOM   10989 C  C   . LYS E 2 72  ? 112.853 136.475 72.901  1.00 74.48  ? 18  LYS C C   1 
ATOM   10990 O  O   . LYS E 2 72  ? 113.614 137.399 72.596  1.00 77.05  ? 18  LYS C O   1 
ATOM   10991 C  CB  . LYS E 2 72  ? 111.233 135.645 71.177  1.00 71.98  ? 18  LYS C CB  1 
ATOM   10992 C  CG  . LYS E 2 72  ? 111.154 137.006 70.517  1.00 78.99  ? 18  LYS C CG  1 
ATOM   10993 C  CD  . LYS E 2 72  ? 109.761 137.251 69.954  1.00 87.04  ? 18  LYS C CD  1 
ATOM   10994 C  CE  . LYS E 2 72  ? 109.608 138.673 69.434  1.00 89.01  ? 18  LYS C CE  1 
ATOM   10995 N  NZ  . LYS E 2 72  ? 108.226 138.934 68.954  1.00 86.88  ? 18  LYS C NZ  1 
ATOM   10996 N  N   . LEU E 2 73  ? 112.268 136.406 74.099  1.00 71.83  ? 19  LEU C N   1 
ATOM   10997 C  CA  . LEU E 2 73  ? 112.506 137.456 75.087  1.00 70.20  ? 19  LEU C CA  1 
ATOM   10998 C  C   . LEU E 2 73  ? 113.972 137.522 75.491  1.00 71.67  ? 19  LEU C C   1 
ATOM   10999 O  O   . LEU E 2 73  ? 114.534 138.612 75.638  1.00 74.36  ? 19  LEU C O   1 
ATOM   11000 C  CB  . LEU E 2 73  ? 111.630 137.241 76.317  1.00 63.89  ? 19  LEU C CB  1 
ATOM   11001 C  CG  . LEU E 2 73  ? 110.156 137.583 76.157  1.00 65.14  ? 19  LEU C CG  1 
ATOM   11002 C  CD1 . LEU E 2 73  ? 109.450 137.411 77.479  1.00 58.37  ? 19  LEU C CD1 1 
ATOM   11003 C  CD2 . LEU E 2 73  ? 109.998 138.994 75.635  1.00 63.73  ? 19  LEU C CD2 1 
ATOM   11004 N  N   . LEU E 2 74  ? 114.609 136.371 75.670  1.00 69.19  ? 20  LEU C N   1 
ATOM   11005 C  CA  . LEU E 2 74  ? 116.001 136.315 76.089  1.00 65.42  ? 20  LEU C CA  1 
ATOM   11006 C  C   . LEU E 2 74  ? 116.978 136.402 74.927  1.00 72.08  ? 20  LEU C C   1 
ATOM   11007 O  O   . LEU E 2 74  ? 118.190 136.376 75.155  1.00 72.47  ? 20  LEU C O   1 
ATOM   11008 C  CB  . LEU E 2 74  ? 116.259 135.032 76.877  1.00 67.50  ? 20  LEU C CB  1 
ATOM   11009 C  CG  . LEU E 2 74  ? 115.311 134.750 78.040  1.00 73.19  ? 20  LEU C CG  1 
ATOM   11010 C  CD1 . LEU E 2 74  ? 115.697 133.451 78.702  1.00 71.51  ? 20  LEU C CD1 1 
ATOM   11011 C  CD2 . LEU E 2 74  ? 115.325 135.881 79.044  1.00 64.78  ? 20  LEU C CD2 1 
ATOM   11012 N  N   . LYS E 2 75  ? 116.489 136.501 73.696  1.00 77.06  ? 21  LYS C N   1 
ATOM   11013 C  CA  . LYS E 2 75  ? 117.367 136.652 72.543  1.00 75.29  ? 21  LYS C CA  1 
ATOM   11014 C  C   . LYS E 2 75  ? 117.963 138.053 72.530  1.00 76.83  ? 21  LYS C C   1 
ATOM   11015 O  O   . LYS E 2 75  ? 117.240 139.042 72.374  1.00 72.85  ? 21  LYS C O   1 
ATOM   11016 C  CB  . LYS E 2 75  ? 116.595 136.392 71.255  1.00 72.81  ? 21  LYS C CB  1 
ATOM   11017 C  CG  . LYS E 2 75  ? 117.407 136.628 69.999  1.00 80.69  ? 21  LYS C CG  1 
ATOM   11018 C  CD  . LYS E 2 75  ? 116.550 136.480 68.757  1.00 88.20  ? 21  LYS C CD  1 
ATOM   11019 C  CE  . LYS E 2 75  ? 117.359 136.714 67.497  1.00 86.18  ? 21  LYS C CE  1 
ATOM   11020 N  NZ  . LYS E 2 75  ? 116.551 136.467 66.273  1.00 85.73  ? 21  LYS C NZ  1 
ATOM   11021 N  N   . GLY E 2 76  ? 119.280 138.139 72.695  1.00 74.56  ? 22  GLY C N   1 
ATOM   11022 C  CA  . GLY E 2 76  ? 119.950 139.420 72.717  1.00 71.31  ? 22  GLY C CA  1 
ATOM   11023 C  C   . GLY E 2 76  ? 119.796 140.195 74.002  1.00 72.14  ? 22  GLY C C   1 
ATOM   11024 O  O   . GLY E 2 76  ? 120.232 141.349 74.067  1.00 74.13  ? 22  GLY C O   1 
ATOM   11025 N  N   . TYR E 2 77  ? 119.189 139.602 75.024  1.00 67.45  ? 23  TYR C N   1 
ATOM   11026 C  CA  . TYR E 2 77  ? 119.028 140.277 76.301  1.00 57.98  ? 23  TYR C CA  1 
ATOM   11027 C  C   . TYR E 2 77  ? 120.389 140.496 76.945  1.00 59.89  ? 23  TYR C C   1 
ATOM   11028 O  O   . TYR E 2 77  ? 121.215 139.581 76.999  1.00 68.15  ? 23  TYR C O   1 
ATOM   11029 C  CB  . TYR E 2 77  ? 118.131 139.445 77.210  1.00 59.97  ? 23  TYR C CB  1 
ATOM   11030 C  CG  . TYR E 2 77  ? 117.714 140.125 78.484  1.00 56.03  ? 23  TYR C CG  1 
ATOM   11031 C  CD1 . TYR E 2 77  ? 116.573 140.905 78.532  1.00 52.32  ? 23  TYR C CD1 1 
ATOM   11032 C  CD2 . TYR E 2 77  ? 118.448 139.971 79.645  1.00 49.61  ? 23  TYR C CD2 1 
ATOM   11033 C  CE1 . TYR E 2 77  ? 116.184 141.516 79.694  1.00 49.23  ? 23  TYR C CE1 1 
ATOM   11034 C  CE2 . TYR E 2 77  ? 118.067 140.581 80.811  1.00 43.93  ? 23  TYR C CE2 1 
ATOM   11035 C  CZ  . TYR E 2 77  ? 116.935 141.351 80.831  1.00 46.21  ? 23  TYR C CZ  1 
ATOM   11036 O  OH  . TYR E 2 77  ? 116.553 141.961 81.998  1.00 50.08  ? 23  TYR C OH  1 
ATOM   11037 N  N   . ASP E 2 78  ? 120.626 141.709 77.429  1.00 55.84  ? 24  ASP C N   1 
ATOM   11038 C  CA  . ASP E 2 78  ? 121.888 142.074 78.064  1.00 57.66  ? 24  ASP C CA  1 
ATOM   11039 C  C   . ASP E 2 78  ? 121.627 142.319 79.544  1.00 52.45  ? 24  ASP C C   1 
ATOM   11040 O  O   . ASP E 2 78  ? 120.947 143.282 79.907  1.00 52.13  ? 24  ASP C O   1 
ATOM   11041 C  CB  . ASP E 2 78  ? 122.492 143.307 77.400  1.00 61.06  ? 24  ASP C CB  1 
ATOM   11042 C  CG  . ASP E 2 78  ? 123.984 143.407 77.615  1.00 63.24  ? 24  ASP C CG  1 
ATOM   11043 O  OD1 . ASP E 2 78  ? 124.579 142.428 78.102  1.00 63.72  ? 24  ASP C OD1 1 
ATOM   11044 O  OD2 . ASP E 2 78  ? 124.564 144.463 77.297  1.00 62.09  ? 24  ASP C OD2 1 
ATOM   11045 N  N   . ILE E 2 79  ? 122.179 141.454 80.398  1.00 48.13  ? 25  ILE C N   1 
ATOM   11046 C  CA  . ILE E 2 79  ? 121.927 141.555 81.833  1.00 48.83  ? 25  ILE C CA  1 
ATOM   11047 C  C   . ILE E 2 79  ? 122.794 142.592 82.520  1.00 51.03  ? 25  ILE C C   1 
ATOM   11048 O  O   . ILE E 2 79  ? 122.595 142.857 83.710  1.00 56.94  ? 25  ILE C O   1 
ATOM   11049 C  CB  . ILE E 2 79  ? 122.147 140.207 82.540  1.00 47.80  ? 25  ILE C CB  1 
ATOM   11050 C  CG1 . ILE E 2 79  ? 123.635 139.881 82.601  1.00 46.14  ? 25  ILE C CG1 1 
ATOM   11051 C  CG2 . ILE E 2 79  ? 121.421 139.114 81.816  1.00 51.82  ? 25  ILE C CG2 1 
ATOM   11052 C  CD1 . ILE E 2 79  ? 123.925 138.510 83.140  1.00 46.71  ? 25  ILE C CD1 1 
ATOM   11053 N  N   . ARG E 2 80  ? 123.760 143.178 81.817  1.00 47.44  ? 26  ARG C N   1 
ATOM   11054 C  CA  . ARG E 2 80  ? 124.618 144.185 82.421  1.00 44.63  ? 26  ARG C CA  1 
ATOM   11055 C  C   . ARG E 2 80  ? 123.994 145.569 82.432  1.00 45.13  ? 26  ARG C C   1 
ATOM   11056 O  O   . ARG E 2 80  ? 124.532 146.462 83.089  1.00 52.78  ? 26  ARG C O   1 
ATOM   11057 C  CB  . ARG E 2 80  ? 125.958 144.238 81.690  1.00 43.77  ? 26  ARG C CB  1 
ATOM   11058 C  CG  . ARG E 2 80  ? 126.718 142.935 81.721  1.00 45.41  ? 26  ARG C CG  1 
ATOM   11059 C  CD  . ARG E 2 80  ? 127.815 142.910 80.682  1.00 52.87  ? 26  ARG C CD  1 
ATOM   11060 N  NE  . ARG E 2 80  ? 127.316 143.247 79.356  1.00 56.64  ? 26  ARG C NE  1 
ATOM   11061 C  CZ  . ARG E 2 80  ? 128.003 143.089 78.233  1.00 56.98  ? 26  ARG C CZ  1 
ATOM   11062 N  NH1 . ARG E 2 80  ? 129.220 142.575 78.235  1.00 50.45  ? 26  ARG C NH1 1 
ATOM   11063 N  NH2 . ARG E 2 80  ? 127.452 143.452 77.079  1.00 55.30  ? 26  ARG C NH2 1 
ATOM   11064 N  N   . LEU E 2 81  ? 122.878 145.769 81.739  1.00 44.64  ? 27  LEU C N   1 
ATOM   11065 C  CA  . LEU E 2 81  ? 122.244 147.073 81.623  1.00 44.25  ? 27  LEU C CA  1 
ATOM   11066 C  C   . LEU E 2 81  ? 120.880 147.038 82.291  1.00 45.06  ? 27  LEU C C   1 
ATOM   11067 O  O   . LEU E 2 81  ? 120.079 146.139 82.026  1.00 47.16  ? 27  LEU C O   1 
ATOM   11068 C  CB  . LEU E 2 81  ? 122.102 147.479 80.157  1.00 42.54  ? 27  LEU C CB  1 
ATOM   11069 C  CG  . LEU E 2 81  ? 123.392 147.512 79.347  1.00 41.48  ? 27  LEU C CG  1 
ATOM   11070 C  CD1 . LEU E 2 81  ? 123.090 147.805 77.897  1.00 38.50  ? 27  LEU C CD1 1 
ATOM   11071 C  CD2 . LEU E 2 81  ? 124.342 148.540 79.914  1.00 39.83  ? 27  LEU C CD2 1 
ATOM   11072 N  N   . ARG E 2 82  ? 120.618 148.023 83.143  1.00 43.22  ? 28  ARG C N   1 
ATOM   11073 C  CA  . ARG E 2 82  ? 119.342 148.124 83.825  1.00 44.02  ? 28  ARG C CA  1 
ATOM   11074 C  C   . ARG E 2 82  ? 118.243 148.517 82.843  1.00 52.57  ? 28  ARG C C   1 
ATOM   11075 O  O   . ARG E 2 82  ? 118.523 149.028 81.758  1.00 53.58  ? 28  ARG C O   1 
ATOM   11076 C  CB  . ARG E 2 82  ? 119.424 149.154 84.946  1.00 44.34  ? 28  ARG C CB  1 
ATOM   11077 C  CG  . ARG E 2 82  ? 119.603 150.569 84.456  1.00 51.09  ? 28  ARG C CG  1 
ATOM   11078 C  CD  . ARG E 2 82  ? 119.250 151.566 85.529  1.00 49.27  ? 28  ARG C CD  1 
ATOM   11079 N  NE  . ARG E 2 82  ? 119.497 152.934 85.093  1.00 55.36  ? 28  ARG C NE  1 
ATOM   11080 C  CZ  . ARG E 2 82  ? 118.589 153.719 84.535  1.00 51.36  ? 28  ARG C CZ  1 
ATOM   11081 N  NH1 . ARG E 2 82  ? 117.357 153.301 84.315  1.00 48.30  ? 28  ARG C NH1 1 
ATOM   11082 N  NH2 . ARG E 2 82  ? 118.923 154.960 84.202  1.00 51.60  ? 28  ARG C NH2 1 
ATOM   11083 N  N   . PRO E 2 83  ? 116.982 148.266 83.190  1.00 50.31  ? 29  PRO C N   1 
ATOM   11084 C  CA  . PRO E 2 83  ? 115.883 148.729 82.338  1.00 50.82  ? 29  PRO C CA  1 
ATOM   11085 C  C   . PRO E 2 83  ? 115.914 150.239 82.180  1.00 56.29  ? 29  PRO C C   1 
ATOM   11086 O  O   . PRO E 2 83  ? 116.186 150.974 83.130  1.00 58.85  ? 29  PRO C O   1 
ATOM   11087 C  CB  . PRO E 2 83  ? 114.634 148.270 83.094  1.00 45.25  ? 29  PRO C CB  1 
ATOM   11088 C  CG  . PRO E 2 83  ? 115.098 147.167 83.953  1.00 44.49  ? 29  PRO C CG  1 
ATOM   11089 C  CD  . PRO E 2 83  ? 116.491 147.491 84.339  1.00 43.03  ? 29  PRO C CD  1 
ATOM   11090 N  N   . ASP E 2 84  ? 115.616 150.697 80.965  1.00 56.11  ? 30  ASP C N   1 
ATOM   11091 C  CA  . ASP E 2 84  ? 115.702 152.111 80.611  1.00 59.22  ? 30  ASP C CA  1 
ATOM   11092 C  C   . ASP E 2 84  ? 117.073 152.680 80.970  1.00 58.54  ? 30  ASP C C   1 
ATOM   11093 O  O   . ASP E 2 84  ? 117.195 153.739 81.587  1.00 60.74  ? 30  ASP C O   1 
ATOM   11094 C  CB  . ASP E 2 84  ? 114.585 152.916 81.274  1.00 63.27  ? 30  ASP C CB  1 
ATOM   11095 C  CG  . ASP E 2 84  ? 113.281 152.839 80.510  1.00 82.72  ? 30  ASP C CG  1 
ATOM   11096 O  OD1 . ASP E 2 84  ? 113.322 152.673 79.273  1.00 89.58  ? 30  ASP C OD1 1 
ATOM   11097 O  OD2 . ASP E 2 84  ? 112.209 152.951 81.144  1.00 88.66  ? 30  ASP C OD2 1 
ATOM   11098 N  N   . PHE E 2 85  ? 118.115 151.946 80.595  1.00 54.20  ? 31  PHE C N   1 
ATOM   11099 C  CA  . PHE E 2 85  ? 119.475 152.418 80.812  1.00 51.31  ? 31  PHE C CA  1 
ATOM   11100 C  C   . PHE E 2 85  ? 119.704 153.722 80.062  1.00 54.69  ? 31  PHE C C   1 
ATOM   11101 O  O   . PHE E 2 85  ? 119.360 153.845 78.884  1.00 60.30  ? 31  PHE C O   1 
ATOM   11102 C  CB  . PHE E 2 85  ? 120.473 151.357 80.359  1.00 46.21  ? 31  PHE C CB  1 
ATOM   11103 C  CG  . PHE E 2 85  ? 121.902 151.689 80.669  1.00 51.52  ? 31  PHE C CG  1 
ATOM   11104 C  CD1 . PHE E 2 85  ? 122.667 152.430 79.787  1.00 52.83  ? 31  PHE C CD1 1 
ATOM   11105 C  CD2 . PHE E 2 85  ? 122.488 151.244 81.835  1.00 51.55  ? 31  PHE C CD2 1 
ATOM   11106 C  CE1 . PHE E 2 85  ? 123.983 152.726 80.074  1.00 50.98  ? 31  PHE C CE1 1 
ATOM   11107 C  CE2 . PHE E 2 85  ? 123.801 151.535 82.122  1.00 46.62  ? 31  PHE C CE2 1 
ATOM   11108 C  CZ  . PHE E 2 85  ? 124.547 152.278 81.242  1.00 47.24  ? 31  PHE C CZ  1 
ATOM   11109 N  N   . GLY E 2 86  ? 120.290 154.696 80.750  1.00 49.76  ? 32  GLY C N   1 
ATOM   11110 C  CA  . GLY E 2 86  ? 120.499 156.012 80.193  1.00 49.37  ? 32  GLY C CA  1 
ATOM   11111 C  C   . GLY E 2 86  ? 119.301 156.931 80.248  1.00 56.07  ? 32  GLY C C   1 
ATOM   11112 O  O   . GLY E 2 86  ? 119.393 158.066 79.771  1.00 59.89  ? 32  GLY C O   1 
ATOM   11113 N  N   . GLY E 2 87  ? 118.183 156.486 80.810  1.00 54.34  ? 33  GLY C N   1 
ATOM   11114 C  CA  . GLY E 2 87  ? 117.001 157.307 80.901  1.00 50.30  ? 33  GLY C CA  1 
ATOM   11115 C  C   . GLY E 2 87  ? 116.524 157.469 82.329  1.00 62.47  ? 33  GLY C C   1 
ATOM   11116 O  O   . GLY E 2 87  ? 117.316 157.473 83.276  1.00 65.32  ? 33  GLY C O   1 
ATOM   11117 N  N   . PRO E 2 88  ? 115.209 157.597 82.511  1.00 64.77  ? 34  PRO C N   1 
ATOM   11118 C  CA  . PRO E 2 88  ? 114.682 157.848 83.849  1.00 58.07  ? 34  PRO C CA  1 
ATOM   11119 C  C   . PRO E 2 88  ? 114.918 156.658 84.762  1.00 57.85  ? 34  PRO C C   1 
ATOM   11120 O  O   . PRO E 2 88  ? 115.037 155.513 84.295  1.00 65.05  ? 34  PRO C O   1 
ATOM   11121 C  CB  . PRO E 2 88  ? 113.181 158.079 83.600  1.00 53.99  ? 34  PRO C CB  1 
ATOM   11122 C  CG  . PRO E 2 88  ? 112.905 157.419 82.309  1.00 59.04  ? 34  PRO C CG  1 
ATOM   11123 C  CD  . PRO E 2 88  ? 114.148 157.559 81.493  1.00 58.60  ? 34  PRO C CD  1 
ATOM   11124 N  N   . PRO E 2 89  ? 115.007 156.883 86.072  1.00 53.34  ? 35  PRO C N   1 
ATOM   11125 C  CA  . PRO E 2 89  ? 115.306 155.783 86.997  1.00 52.16  ? 35  PRO C CA  1 
ATOM   11126 C  C   . PRO E 2 89  ? 114.240 154.702 86.969  1.00 54.31  ? 35  PRO C C   1 
ATOM   11127 O  O   . PRO E 2 89  ? 113.055 154.971 86.775  1.00 58.52  ? 35  PRO C O   1 
ATOM   11128 C  CB  . PRO E 2 89  ? 115.344 156.472 88.364  1.00 46.37  ? 35  PRO C CB  1 
ATOM   11129 C  CG  . PRO E 2 89  ? 115.541 157.902 88.074  1.00 53.26  ? 35  PRO C CG  1 
ATOM   11130 C  CD  . PRO E 2 89  ? 114.883 158.169 86.771  1.00 54.54  ? 35  PRO C CD  1 
ATOM   11131 N  N   . VAL E 2 90  ? 114.677 153.466 87.183  1.00 49.25  ? 36  VAL C N   1 
ATOM   11132 C  CA  . VAL E 2 90  ? 113.755 152.351 87.359  1.00 46.97  ? 36  VAL C CA  1 
ATOM   11133 C  C   . VAL E 2 90  ? 113.288 152.336 88.808  1.00 47.45  ? 36  VAL C C   1 
ATOM   11134 O  O   . VAL E 2 90  ? 114.086 152.512 89.733  1.00 45.17  ? 36  VAL C O   1 
ATOM   11135 C  CB  . VAL E 2 90  ? 114.419 151.022 86.957  1.00 44.90  ? 36  VAL C CB  1 
ATOM   11136 C  CG1 . VAL E 2 90  ? 115.584 150.689 87.861  1.00 40.29  ? 36  VAL C CG1 1 
ATOM   11137 C  CG2 . VAL E 2 90  ? 113.413 149.901 86.969  1.00 42.60  ? 36  VAL C CG2 1 
ATOM   11138 N  N   . CYS E 2 91  ? 111.987 152.165 89.009  1.00 48.49  ? 37  CYS C N   1 
ATOM   11139 C  CA  . CYS E 2 91  ? 111.391 152.210 90.337  1.00 43.90  ? 37  CYS C CA  1 
ATOM   11140 C  C   . CYS E 2 91  ? 111.088 150.794 90.801  1.00 36.83  ? 37  CYS C C   1 
ATOM   11141 O  O   . CYS E 2 91  ? 110.384 150.050 90.115  1.00 42.29  ? 37  CYS C O   1 
ATOM   11142 C  CB  . CYS E 2 91  ? 110.123 153.059 90.334  1.00 46.35  ? 37  CYS C CB  1 
ATOM   11143 S  SG  . CYS E 2 91  ? 110.346 154.708 89.648  1.00 71.45  ? 37  CYS C SG  1 
ATOM   11144 N  N   . VAL E 2 92  ? 111.594 150.441 91.975  1.00 33.34  ? 38  VAL C N   1 
ATOM   11145 C  CA  . VAL E 2 92  ? 111.461 149.105 92.538  1.00 32.40  ? 38  VAL C CA  1 
ATOM   11146 C  C   . VAL E 2 92  ? 110.578 149.208 93.772  1.00 35.10  ? 38  VAL C C   1 
ATOM   11147 O  O   . VAL E 2 92  ? 110.879 149.976 94.691  1.00 41.25  ? 38  VAL C O   1 
ATOM   11148 C  CB  . VAL E 2 92  ? 112.833 148.513 92.887  1.00 31.89  ? 38  VAL C CB  1 
ATOM   11149 C  CG1 . VAL E 2 92  ? 112.724 147.047 93.189  1.00 31.66  ? 38  VAL C CG1 1 
ATOM   11150 C  CG2 . VAL E 2 92  ? 113.801 148.744 91.754  1.00 31.11  ? 38  VAL C CG2 1 
ATOM   11151 N  N   . GLY E 2 93  ? 109.484 148.456 93.790  1.00 30.68  ? 39  GLY C N   1 
ATOM   11152 C  CA  . GLY E 2 93  ? 108.614 148.383 94.951  1.00 31.70  ? 39  GLY C CA  1 
ATOM   11153 C  C   . GLY E 2 93  ? 108.928 147.136 95.758  1.00 35.66  ? 39  GLY C C   1 
ATOM   11154 O  O   . GLY E 2 93  ? 109.287 146.105 95.201  1.00 37.93  ? 39  GLY C O   1 
ATOM   11155 N  N   . MET E 2 94  ? 108.783 147.233 97.074  1.00 35.85  ? 40  MET C N   1 
ATOM   11156 C  CA  . MET E 2 94  ? 109.192 146.147 97.950  1.00 34.37  ? 40  MET C CA  1 
ATOM   11157 C  C   . MET E 2 94  ? 108.089 145.768 98.922  1.00 33.71  ? 40  MET C C   1 
ATOM   11158 O  O   . MET E 2 94  ? 107.366 146.628 99.428  1.00 37.87  ? 40  MET C O   1 
ATOM   11159 C  CB  . MET E 2 94  ? 110.458 146.517 98.712  1.00 31.92  ? 40  MET C CB  1 
ATOM   11160 C  CG  . MET E 2 94  ? 111.620 146.778 97.785  1.00 35.99  ? 40  MET C CG  1 
ATOM   11161 S  SD  . MET E 2 94  ? 113.141 147.280 98.577  1.00 64.98  ? 40  MET C SD  1 
ATOM   11162 C  CE  . MET E 2 94  ? 114.149 147.521 97.129  1.00 35.77  ? 40  MET C CE  1 
ATOM   11163 N  N   . ASN E 2 95  ? 107.968 144.466 99.164  1.00 33.12  ? 41  ASN C N   1 
ATOM   11164 C  CA  . ASN E 2 95  ? 107.101 143.904 100.188 1.00 30.56  ? 41  ASN C CA  1 
ATOM   11165 C  C   . ASN E 2 95  ? 107.916 142.965 101.053 1.00 32.26  ? 41  ASN C C   1 
ATOM   11166 O  O   . ASN E 2 95  ? 108.831 142.299 100.565 1.00 33.89  ? 41  ASN C O   1 
ATOM   11167 C  CB  . ASN E 2 95  ? 105.935 143.125 99.595  1.00 30.74  ? 41  ASN C CB  1 
ATOM   11168 C  CG  . ASN E 2 95  ? 105.028 143.978 98.783  1.00 39.42  ? 41  ASN C CG  1 
ATOM   11169 O  OD1 . ASN E 2 95  ? 104.679 143.632 97.661  1.00 51.79  ? 41  ASN C OD1 1 
ATOM   11170 N  ND2 . ASN E 2 95  ? 104.632 145.112 99.335  1.00 43.88  ? 41  ASN C ND2 1 
ATOM   11171 N  N   . ILE E 2 96  ? 107.586 142.914 102.335 1.00 28.55  ? 42  ILE C N   1 
ATOM   11172 C  CA  . ILE E 2 96  ? 108.213 141.991 103.268 1.00 27.43  ? 42  ILE C CA  1 
ATOM   11173 C  C   . ILE E 2 96  ? 107.114 141.295 104.050 1.00 29.72  ? 42  ILE C C   1 
ATOM   11174 O  O   . ILE E 2 96  ? 106.197 141.950 104.549 1.00 37.32  ? 42  ILE C O   1 
ATOM   11175 C  CB  . ILE E 2 96  ? 109.184 142.708 104.220 1.00 26.61  ? 42  ILE C CB  1 
ATOM   11176 C  CG1 . ILE E 2 96  ? 110.263 143.441 103.435 1.00 22.39  ? 42  ILE C CG1 1 
ATOM   11177 C  CG2 . ILE E 2 96  ? 109.827 141.721 105.155 1.00 26.25  ? 42  ILE C CG2 1 
ATOM   11178 C  CD1 . ILE E 2 96  ? 111.171 144.248 104.298 1.00 23.51  ? 42  ILE C CD1 1 
ATOM   11179 N  N   . ASP E 2 97  ? 107.187 139.973 104.129 1.00 29.57  ? 43  ASP C N   1 
ATOM   11180 C  CA  . ASP E 2 97  ? 106.306 139.181 104.981 1.00 28.56  ? 43  ASP C CA  1 
ATOM   11181 C  C   . ASP E 2 97  ? 107.168 138.549 106.058 1.00 28.51  ? 43  ASP C C   1 
ATOM   11182 O  O   . ASP E 2 97  ? 107.978 137.668 105.761 1.00 33.68  ? 43  ASP C O   1 
ATOM   11183 C  CB  . ASP E 2 97  ? 105.569 138.110 104.186 1.00 33.78  ? 43  ASP C CB  1 
ATOM   11184 C  CG  . ASP E 2 97  ? 104.792 138.674 103.030 1.00 52.31  ? 43  ASP C CG  1 
ATOM   11185 O  OD1 . ASP E 2 97  ? 104.791 139.909 102.857 1.00 53.68  ? 43  ASP C OD1 1 
ATOM   11186 O  OD2 . ASP E 2 97  ? 104.181 137.878 102.288 1.00 54.78  ? 43  ASP C OD2 1 
ATOM   11187 N  N   . ILE E 2 98  ? 107.007 138.993 107.296 1.00 26.16  ? 44  ILE C N   1 
ATOM   11188 C  CA  . ILE E 2 98  ? 107.825 138.481 108.386 1.00 26.54  ? 44  ILE C CA  1 
ATOM   11189 C  C   . ILE E 2 98  ? 107.282 137.129 108.816 1.00 31.59  ? 44  ILE C C   1 
ATOM   11190 O  O   . ILE E 2 98  ? 106.092 136.992 109.116 1.00 36.43  ? 44  ILE C O   1 
ATOM   11191 C  CB  . ILE E 2 98  ? 107.843 139.455 109.569 1.00 32.38  ? 44  ILE C CB  1 
ATOM   11192 C  CG1 . ILE E 2 98  ? 108.105 140.884 109.101 1.00 32.81  ? 44  ILE C CG1 1 
ATOM   11193 C  CG2 . ILE E 2 98  ? 108.890 139.022 110.563 1.00 31.31  ? 44  ILE C CG2 1 
ATOM   11194 C  CD1 . ILE E 2 98  ? 109.522 141.144 108.721 1.00 30.91  ? 44  ILE C CD1 1 
ATOM   11195 N  N   . ALA E 2 99  ? 108.147 136.123 108.846 1.00 30.22  ? 45  ALA C N   1 
ATOM   11196 C  CA  . ALA E 2 99  ? 107.757 134.813 109.327 1.00 35.28  ? 45  ALA C CA  1 
ATOM   11197 C  C   . ALA E 2 99  ? 108.136 134.584 110.778 1.00 41.21  ? 45  ALA C C   1 
ATOM   11198 O  O   . ALA E 2 99  ? 107.396 133.911 111.498 1.00 55.50  ? 45  ALA C O   1 
ATOM   11199 C  CB  . ALA E 2 99  ? 108.385 133.723 108.456 1.00 28.99  ? 45  ALA C CB  1 
ATOM   11200 N  N   . SER E 2 100 ? 109.263 135.128 111.227 1.00 32.28  ? 46  SER C N   1 
ATOM   11201 C  CA  . SER E 2 100 ? 109.668 134.985 112.615 1.00 34.34  ? 46  SER C CA  1 
ATOM   11202 C  C   . SER E 2 100 ? 110.733 136.018 112.932 1.00 38.98  ? 46  SER C C   1 
ATOM   11203 O  O   . SER E 2 100 ? 111.402 136.540 112.039 1.00 41.76  ? 46  SER C O   1 
ATOM   11204 C  CB  . SER E 2 100 ? 110.195 133.580 112.900 1.00 38.57  ? 46  SER C CB  1 
ATOM   11205 O  OG  . SER E 2 100 ? 111.462 133.396 112.309 1.00 39.01  ? 46  SER C OG  1 
ATOM   11206 N  N   . ILE E 2 101 ? 110.874 136.312 114.221 1.00 39.86  ? 47  ILE C N   1 
ATOM   11207 C  CA  . ILE E 2 101 ? 112.000 137.070 114.759 1.00 35.03  ? 47  ILE C CA  1 
ATOM   11208 C  C   . ILE E 2 101 ? 112.573 136.205 115.871 1.00 41.87  ? 47  ILE C C   1 
ATOM   11209 O  O   . ILE E 2 101 ? 111.990 136.111 116.954 1.00 48.95  ? 47  ILE C O   1 
ATOM   11210 C  CB  . ILE E 2 101 ? 111.593 138.449 115.277 1.00 30.59  ? 47  ILE C CB  1 
ATOM   11211 C  CG1 . ILE E 2 101 ? 110.984 139.272 114.145 1.00 31.38  ? 47  ILE C CG1 1 
ATOM   11212 C  CG2 . ILE E 2 101 ? 112.787 139.169 115.842 1.00 34.41  ? 47  ILE C CG2 1 
ATOM   11213 C  CD1 . ILE E 2 101 ? 110.603 140.663 114.549 1.00 32.29  ? 47  ILE C CD1 1 
ATOM   11214 N  N   . ASP E 2 102 ? 113.713 135.570 115.612 1.00 42.05  ? 48  ASP C N   1 
ATOM   11215 C  CA  . ASP E 2 102 ? 114.111 134.415 116.409 1.00 44.43  ? 48  ASP C CA  1 
ATOM   11216 C  C   . ASP E 2 102 ? 114.669 134.809 117.769 1.00 47.97  ? 48  ASP C C   1 
ATOM   11217 O  O   . ASP E 2 102 ? 114.066 134.514 118.805 1.00 60.27  ? 48  ASP C O   1 
ATOM   11218 C  CB  . ASP E 2 102 ? 115.136 133.580 115.641 1.00 50.32  ? 48  ASP C CB  1 
ATOM   11219 C  CG  . ASP E 2 102 ? 114.529 132.861 114.456 1.00 67.29  ? 48  ASP C CG  1 
ATOM   11220 O  OD1 . ASP E 2 102 ? 113.404 132.334 114.593 1.00 69.07  ? 48  ASP C OD1 1 
ATOM   11221 O  OD2 . ASP E 2 102 ? 115.173 132.823 113.386 1.00 69.27  ? 48  ASP C OD2 1 
ATOM   11222 N  N   . MET E 2 103 ? 115.819 135.478 117.793 1.00 39.31  ? 49  MET C N   1 
ATOM   11223 C  CA  . MET E 2 103 ? 116.581 135.602 119.034 1.00 42.71  ? 49  MET C CA  1 
ATOM   11224 C  C   . MET E 2 103 ? 117.164 137.003 119.156 1.00 41.75  ? 49  MET C C   1 
ATOM   11225 O  O   . MET E 2 103 ? 118.204 137.304 118.568 1.00 46.18  ? 49  MET C O   1 
ATOM   11226 C  CB  . MET E 2 103 ? 117.675 134.546 119.098 1.00 41.31  ? 49  MET C CB  1 
ATOM   11227 C  CG  . MET E 2 103 ? 118.258 134.190 117.754 1.00 49.39  ? 49  MET C CG  1 
ATOM   11228 S  SD  . MET E 2 103 ? 119.260 132.696 117.789 1.00 86.83  ? 49  MET C SD  1 
ATOM   11229 C  CE  . MET E 2 103 ? 119.799 132.633 116.084 1.00 59.82  ? 49  MET C CE  1 
ATOM   11230 N  N   . VAL E 2 104 ? 116.506 137.840 119.946 1.00 40.41  ? 50  VAL C N   1 
ATOM   11231 C  CA  . VAL E 2 104 ? 117.050 139.138 120.309 1.00 36.24  ? 50  VAL C CA  1 
ATOM   11232 C  C   . VAL E 2 104 ? 118.099 138.930 121.389 1.00 43.01  ? 50  VAL C C   1 
ATOM   11233 O  O   . VAL E 2 104 ? 117.823 138.316 122.425 1.00 54.64  ? 50  VAL C O   1 
ATOM   11234 C  CB  . VAL E 2 104 ? 115.938 140.076 120.796 1.00 34.51  ? 50  VAL C CB  1 
ATOM   11235 C  CG1 . VAL E 2 104 ? 116.526 141.385 121.250 1.00 34.44  ? 50  VAL C CG1 1 
ATOM   11236 C  CG2 . VAL E 2 104 ? 114.919 140.293 119.707 1.00 30.83  ? 50  VAL C CG2 1 
ATOM   11237 N  N   . SER E 2 105 ? 119.305 139.433 121.149 1.00 39.48  ? 51  SER C N   1 
ATOM   11238 C  CA  . SER E 2 105 ? 120.439 139.213 122.037 1.00 39.12  ? 51  SER C CA  1 
ATOM   11239 C  C   . SER E 2 105 ? 121.013 140.548 122.478 1.00 42.24  ? 51  SER C C   1 
ATOM   11240 O  O   . SER E 2 105 ? 121.384 141.374 121.639 1.00 43.98  ? 51  SER C O   1 
ATOM   11241 C  CB  . SER E 2 105 ? 121.513 138.381 121.346 1.00 37.62  ? 51  SER C CB  1 
ATOM   11242 O  OG  . SER E 2 105 ? 122.669 138.301 122.148 1.00 45.35  ? 51  SER C OG  1 
ATOM   11243 N  N   . GLU E 2 106 ? 121.094 140.754 123.792 1.00 43.39  ? 52  GLU C N   1 
ATOM   11244 C  CA  . GLU E 2 106 ? 121.776 141.929 124.320 1.00 42.92  ? 52  GLU C CA  1 
ATOM   11245 C  C   . GLU E 2 106 ? 123.286 141.772 124.251 1.00 41.96  ? 52  GLU C C   1 
ATOM   11246 O  O   . GLU E 2 106 ? 124.001 142.745 123.995 1.00 44.85  ? 52  GLU C O   1 
ATOM   11247 C  CB  . GLU E 2 106 ? 121.353 142.189 125.764 1.00 48.19  ? 52  GLU C CB  1 
ATOM   11248 C  CG  . GLU E 2 106 ? 119.932 142.667 125.940 1.00 51.85  ? 52  GLU C CG  1 
ATOM   11249 C  CD  . GLU E 2 106 ? 118.922 141.546 125.879 1.00 63.47  ? 52  GLU C CD  1 
ATOM   11250 O  OE1 . GLU E 2 106 ? 119.331 140.378 125.724 1.00 57.67  ? 52  GLU C OE1 1 
ATOM   11251 O  OE2 . GLU E 2 106 ? 117.714 141.836 125.990 1.00 65.71  ? 52  GLU C OE2 1 
ATOM   11252 N  N   . VAL E 2 107 ? 123.782 140.558 124.486 1.00 42.33  ? 53  VAL C N   1 
ATOM   11253 C  CA  . VAL E 2 107 ? 125.222 140.325 124.506 1.00 44.62  ? 53  VAL C CA  1 
ATOM   11254 C  C   . VAL E 2 107 ? 125.825 140.554 123.128 1.00 47.60  ? 53  VAL C C   1 
ATOM   11255 O  O   . VAL E 2 107 ? 126.883 141.177 122.995 1.00 50.42  ? 53  VAL C O   1 
ATOM   11256 C  CB  . VAL E 2 107 ? 125.515 138.910 125.031 1.00 39.50  ? 53  VAL C CB  1 
ATOM   11257 C  CG1 . VAL E 2 107 ? 126.993 138.721 125.233 1.00 37.09  ? 53  VAL C CG1 1 
ATOM   11258 C  CG2 . VAL E 2 107 ? 124.780 138.678 126.322 1.00 45.46  ? 53  VAL C CG2 1 
ATOM   11259 N  N   . ASN E 2 108 ? 125.170 140.056 122.085 1.00 43.16  ? 54  ASN C N   1 
ATOM   11260 C  CA  . ASN E 2 108 ? 125.651 140.222 120.723 1.00 40.62  ? 54  ASN C CA  1 
ATOM   11261 C  C   . ASN E 2 108 ? 125.143 141.487 120.054 1.00 40.28  ? 54  ASN C C   1 
ATOM   11262 O  O   . ASN E 2 108 ? 125.660 141.850 118.994 1.00 42.69  ? 54  ASN C O   1 
ATOM   11263 C  CB  . ASN E 2 108 ? 125.252 139.019 119.874 1.00 41.16  ? 54  ASN C CB  1 
ATOM   11264 C  CG  . ASN E 2 108 ? 125.963 137.762 120.290 1.00 47.58  ? 54  ASN C CG  1 
ATOM   11265 O  OD1 . ASN E 2 108 ? 125.335 136.764 120.627 1.00 59.83  ? 54  ASN C OD1 1 
ATOM   11266 N  ND2 . ASN E 2 108 ? 127.284 137.802 120.276 1.00 44.93  ? 54  ASN C ND2 1 
ATOM   11267 N  N   . MET E 2 109 ? 124.153 142.159 120.638 1.00 38.83  ? 55  MET C N   1 
ATOM   11268 C  CA  . MET E 2 109 ? 123.603 143.397 120.091 1.00 38.65  ? 55  MET C CA  1 
ATOM   11269 C  C   . MET E 2 109 ? 123.057 143.191 118.680 1.00 40.64  ? 55  MET C C   1 
ATOM   11270 O  O   . MET E 2 109 ? 123.354 143.953 117.761 1.00 43.44  ? 55  MET C O   1 
ATOM   11271 C  CB  . MET E 2 109 ? 124.647 144.516 120.108 1.00 38.72  ? 55  MET C CB  1 
ATOM   11272 C  CG  . MET E 2 109 ? 124.951 145.083 121.474 1.00 43.41  ? 55  MET C CG  1 
ATOM   11273 S  SD  . MET E 2 109 ? 123.611 146.111 122.078 1.00 66.42  ? 55  MET C SD  1 
ATOM   11274 C  CE  . MET E 2 109 ? 124.356 146.817 123.538 1.00 50.51  ? 55  MET C CE  1 
ATOM   11275 N  N   . ASP E 2 110 ? 122.244 142.154 118.512 1.00 38.02  ? 56  ASP C N   1 
ATOM   11276 C  CA  . ASP E 2 110 ? 121.672 141.853 117.206 1.00 34.77  ? 56  ASP C CA  1 
ATOM   11277 C  C   . ASP E 2 110 ? 120.409 141.025 117.393 1.00 32.95  ? 56  ASP C C   1 
ATOM   11278 O  O   . ASP E 2 110 ? 120.063 140.621 118.504 1.00 38.67  ? 56  ASP C O   1 
ATOM   11279 C  CB  . ASP E 2 110 ? 122.688 141.144 116.304 1.00 35.76  ? 56  ASP C CB  1 
ATOM   11280 C  CG  . ASP E 2 110 ? 123.175 139.825 116.871 1.00 43.59  ? 56  ASP C CG  1 
ATOM   11281 O  OD1 . ASP E 2 110 ? 122.543 139.272 117.792 1.00 47.65  ? 56  ASP C OD1 1 
ATOM   11282 O  OD2 . ASP E 2 110 ? 124.216 139.336 116.392 1.00 44.13  ? 56  ASP C OD2 1 
ATOM   11283 N  N   . TYR E 2 111 ? 119.725 140.771 116.283 1.00 28.67  ? 57  TYR C N   1 
ATOM   11284 C  CA  . TYR E 2 111 ? 118.526 139.947 116.284 1.00 29.30  ? 57  TYR C CA  1 
ATOM   11285 C  C   . TYR E 2 111 ? 118.435 139.219 114.953 1.00 31.83  ? 57  TYR C C   1 
ATOM   11286 O  O   . TYR E 2 111 ? 119.023 139.637 113.958 1.00 34.00  ? 57  TYR C O   1 
ATOM   11287 C  CB  . TYR E 2 111 ? 117.272 140.787 116.527 1.00 27.67  ? 57  TYR C CB  1 
ATOM   11288 C  CG  . TYR E 2 111 ? 116.982 141.752 115.412 1.00 29.97  ? 57  TYR C CG  1 
ATOM   11289 C  CD1 . TYR E 2 111 ? 117.670 142.946 115.313 1.00 32.49  ? 57  TYR C CD1 1 
ATOM   11290 C  CD2 . TYR E 2 111 ? 116.028 141.466 114.455 1.00 30.35  ? 57  TYR C CD2 1 
ATOM   11291 C  CE1 . TYR E 2 111 ? 117.418 143.823 114.296 1.00 38.15  ? 57  TYR C CE1 1 
ATOM   11292 C  CE2 . TYR E 2 111 ? 115.769 142.336 113.439 1.00 33.34  ? 57  TYR C CE2 1 
ATOM   11293 C  CZ  . TYR E 2 111 ? 116.466 143.513 113.363 1.00 41.53  ? 57  TYR C CZ  1 
ATOM   11294 O  OH  . TYR E 2 111 ? 116.205 144.388 112.341 1.00 46.10  ? 57  TYR C OH  1 
ATOM   11295 N  N   . THR E 2 112 ? 117.687 138.122 114.937 1.00 31.53  ? 58  THR C N   1 
ATOM   11296 C  CA  . THR E 2 112 ? 117.520 137.302 113.744 1.00 27.45  ? 58  THR C CA  1 
ATOM   11297 C  C   . THR E 2 112 ? 116.111 137.470 113.192 1.00 30.26  ? 58  THR C C   1 
ATOM   11298 O  O   . THR E 2 112 ? 115.156 137.630 113.952 1.00 41.87  ? 58  THR C O   1 
ATOM   11299 C  CB  . THR E 2 112 ? 117.795 135.832 114.049 1.00 32.40  ? 58  THR C CB  1 
ATOM   11300 O  OG1 . THR E 2 112 ? 119.097 135.707 114.627 1.00 38.44  ? 58  THR C OG1 1 
ATOM   11301 C  CG2 . THR E 2 112 ? 117.765 135.013 112.787 1.00 29.33  ? 58  THR C CG2 1 
ATOM   11302 N  N   . LEU E 2 113 ? 115.986 137.432 111.869 1.00 26.60  ? 59  LEU C N   1 
ATOM   11303 C  CA  . LEU E 2 113 ? 114.734 137.746 111.198 1.00 26.72  ? 59  LEU C CA  1 
ATOM   11304 C  C   . LEU E 2 113 ? 114.596 136.887 109.952 1.00 30.18  ? 59  LEU C C   1 
ATOM   11305 O  O   . LEU E 2 113 ? 115.509 136.849 109.127 1.00 35.39  ? 59  LEU C O   1 
ATOM   11306 C  CB  . LEU E 2 113 ? 114.705 139.231 110.831 1.00 28.51  ? 59  LEU C CB  1 
ATOM   11307 C  CG  . LEU E 2 113 ? 113.606 139.809 109.953 1.00 32.85  ? 59  LEU C CG  1 
ATOM   11308 C  CD1 . LEU E 2 113 ? 112.362 140.056 110.754 1.00 35.53  ? 59  LEU C CD1 1 
ATOM   11309 C  CD2 . LEU E 2 113 ? 114.088 141.095 109.343 1.00 35.87  ? 59  LEU C CD2 1 
ATOM   11310 N  N   . THR E 2 114 ? 113.462 136.213 109.805 1.00 26.83  ? 60  THR C N   1 
ATOM   11311 C  CA  . THR E 2 114 ? 113.164 135.427 108.613 1.00 23.83  ? 60  THR C CA  1 
ATOM   11312 C  C   . THR E 2 114 ? 112.004 136.075 107.871 1.00 27.57  ? 60  THR C C   1 
ATOM   11313 O  O   . THR E 2 114 ? 111.000 136.436 108.487 1.00 33.45  ? 60  THR C O   1 
ATOM   11314 C  CB  . THR E 2 114 ? 112.833 133.982 108.978 1.00 27.31  ? 60  THR C CB  1 
ATOM   11315 O  OG1 . THR E 2 114 ? 113.911 133.428 109.733 1.00 36.80  ? 60  THR C OG1 1 
ATOM   11316 C  CG2 . THR E 2 114 ? 112.653 133.148 107.735 1.00 23.06  ? 60  THR C CG2 1 
ATOM   11317 N  N   . MET E 2 115 ? 112.137 136.224 106.556 1.00 27.12  ? 61  MET C N   1 
ATOM   11318 C  CA  . MET E 2 115 ? 111.143 136.972 105.804 1.00 24.88  ? 61  MET C CA  1 
ATOM   11319 C  C   . MET E 2 115 ? 111.040 136.469 104.374 1.00 26.13  ? 61  MET C C   1 
ATOM   11320 O  O   . MET E 2 115 ? 111.937 135.810 103.848 1.00 28.99  ? 61  MET C O   1 
ATOM   11321 C  CB  . MET E 2 115 ? 111.467 138.462 105.797 1.00 27.67  ? 61  MET C CB  1 
ATOM   11322 C  CG  . MET E 2 115 ? 112.866 138.757 105.353 1.00 29.32  ? 61  MET C CG  1 
ATOM   11323 S  SD  . MET E 2 115 ? 113.245 140.503 105.394 1.00 53.98  ? 61  MET C SD  1 
ATOM   11324 C  CE  . MET E 2 115 ? 114.973 140.440 104.970 1.00 32.78  ? 61  MET C CE  1 
ATOM   11325 N  N   . TYR E 2 116 ? 109.904 136.793 103.763 1.00 28.05  ? 62  TYR C N   1 
ATOM   11326 C  CA  . TYR E 2 116 ? 109.688 136.710 102.323 1.00 25.77  ? 62  TYR C CA  1 
ATOM   11327 C  C   . TYR E 2 116 ? 109.864 138.120 101.778 1.00 28.29  ? 62  TYR C C   1 
ATOM   11328 O  O   . TYR E 2 116 ? 109.108 139.024 102.142 1.00 35.24  ? 62  TYR C O   1 
ATOM   11329 C  CB  . TYR E 2 116 ? 108.299 136.173 101.995 1.00 22.54  ? 62  TYR C CB  1 
ATOM   11330 C  CG  . TYR E 2 116 ? 108.003 134.802 102.543 1.00 22.89  ? 62  TYR C CG  1 
ATOM   11331 C  CD1 . TYR E 2 116 ? 107.805 134.605 103.896 1.00 23.48  ? 62  TYR C CD1 1 
ATOM   11332 C  CD2 . TYR E 2 116 ? 107.906 133.709 101.705 1.00 26.79  ? 62  TYR C CD2 1 
ATOM   11333 C  CE1 . TYR E 2 116 ? 107.536 133.365 104.398 1.00 25.97  ? 62  TYR C CE1 1 
ATOM   11334 C  CE2 . TYR E 2 116 ? 107.637 132.463 102.201 1.00 24.37  ? 62  TYR C CE2 1 
ATOM   11335 C  CZ  . TYR E 2 116 ? 107.451 132.297 103.549 1.00 25.87  ? 62  TYR C CZ  1 
ATOM   11336 O  OH  . TYR E 2 116 ? 107.175 131.054 104.056 1.00 30.28  ? 62  TYR C OH  1 
ATOM   11337 N  N   . PHE E 2 117 ? 110.860 138.306 100.925 1.00 23.45  ? 63  PHE C N   1 
ATOM   11338 C  CA  . PHE E 2 117 ? 111.238 139.613 100.411 1.00 24.52  ? 63  PHE C CA  1 
ATOM   11339 C  C   . PHE E 2 117 ? 110.908 139.669 98.926  1.00 28.45  ? 63  PHE C C   1 
ATOM   11340 O  O   . PHE E 2 117 ? 111.529 138.962 98.125  1.00 32.55  ? 63  PHE C O   1 
ATOM   11341 C  CB  . PHE E 2 117 ? 112.728 139.839 100.661 1.00 27.64  ? 63  PHE C CB  1 
ATOM   11342 C  CG  . PHE E 2 117 ? 113.201 141.221 100.357 1.00 31.54  ? 63  PHE C CG  1 
ATOM   11343 C  CD1 . PHE E 2 117 ? 112.821 142.282 101.144 1.00 33.69  ? 63  PHE C CD1 1 
ATOM   11344 C  CD2 . PHE E 2 117 ? 114.059 141.455 99.302  1.00 27.86  ? 63  PHE C CD2 1 
ATOM   11345 C  CE1 . PHE E 2 117 ? 113.262 143.549 100.867 1.00 31.72  ? 63  PHE C CE1 1 
ATOM   11346 C  CE2 . PHE E 2 117 ? 114.500 142.716 99.030  1.00 26.28  ? 63  PHE C CE2 1 
ATOM   11347 C  CZ  . PHE E 2 117 ? 114.103 143.763 99.810  1.00 29.25  ? 63  PHE C CZ  1 
ATOM   11348 N  N   . GLN E 2 118 ? 109.924 140.487 98.559  1.00 28.35  ? 64  GLN C N   1 
ATOM   11349 C  CA  . GLN E 2 118 ? 109.425 140.556 97.190  1.00 29.38  ? 64  GLN C CA  1 
ATOM   11350 C  C   . GLN E 2 118 ? 109.774 141.907 96.588  1.00 33.35  ? 64  GLN C C   1 
ATOM   11351 O  O   . GLN E 2 118 ? 109.542 142.945 97.213  1.00 38.19  ? 64  GLN C O   1 
ATOM   11352 C  CB  . GLN E 2 118 ? 107.914 140.333 97.139  1.00 26.71  ? 64  GLN C CB  1 
ATOM   11353 C  CG  . GLN E 2 118 ? 107.493 138.886 97.213  1.00 32.33  ? 64  GLN C CG  1 
ATOM   11354 C  CD  . GLN E 2 118 ? 107.316 138.405 98.629  1.00 39.11  ? 64  GLN C CD  1 
ATOM   11355 O  OE1 . GLN E 2 118 ? 106.808 139.127 99.482  1.00 37.14  ? 64  GLN C OE1 1 
ATOM   11356 N  NE2 . GLN E 2 118 ? 107.732 137.173 98.889  1.00 40.06  ? 64  GLN C NE2 1 
ATOM   11357 N  N   . GLN E 2 119 ? 110.320 141.890 95.376  1.00 33.96  ? 65  GLN C N   1 
ATOM   11358 C  CA  . GLN E 2 119 ? 110.643 143.094 94.629  1.00 30.23  ? 65  GLN C CA  1 
ATOM   11359 C  C   . GLN E 2 119 ? 109.850 143.124 93.333  1.00 34.04  ? 65  GLN C C   1 
ATOM   11360 O  O   . GLN E 2 119 ? 109.636 142.090 92.697  1.00 38.15  ? 65  GLN C O   1 
ATOM   11361 C  CB  . GLN E 2 119 ? 112.137 143.175 94.342  1.00 26.94  ? 65  GLN C CB  1 
ATOM   11362 C  CG  . GLN E 2 119 ? 112.960 143.215 95.602  1.00 29.65  ? 65  GLN C CG  1 
ATOM   11363 C  CD  . GLN E 2 119 ? 114.416 143.441 95.342  1.00 32.34  ? 65  GLN C CD  1 
ATOM   11364 O  OE1 . GLN E 2 119 ? 114.834 144.551 95.038  1.00 36.94  ? 65  GLN C OE1 1 
ATOM   11365 N  NE2 . GLN E 2 119 ? 115.207 142.387 95.459  1.00 32.73  ? 65  GLN C NE2 1 
ATOM   11366 N  N   . TYR E 2 120 ? 109.414 144.320 92.960  1.00 32.84  ? 66  TYR C N   1 
ATOM   11367 C  CA  A TYR E 2 120 ? 108.501 144.531 91.847  0.50 33.93  ? 66  TYR C CA  1 
ATOM   11368 C  CA  B TYR E 2 120 ? 108.509 144.527 91.835  0.50 34.02  ? 66  TYR C CA  1 
ATOM   11369 C  C   . TYR E 2 120 ? 109.060 145.638 90.969  1.00 35.43  ? 66  TYR C C   1 
ATOM   11370 O  O   . TYR E 2 120 ? 109.196 146.775 91.428  1.00 42.47  ? 66  TYR C O   1 
ATOM   11371 C  CB  A TYR E 2 120 ? 107.129 144.905 92.402  0.50 36.85  ? 66  TYR C CB  1 
ATOM   11372 C  CB  B TYR E 2 120 ? 107.105 144.917 92.291  0.50 36.72  ? 66  TYR C CB  1 
ATOM   11373 C  CG  A TYR E 2 120 ? 105.968 144.934 91.448  0.50 40.89  ? 66  TYR C CG  1 
ATOM   11374 C  CG  B TYR E 2 120 ? 106.261 143.837 92.910  0.50 38.47  ? 66  TYR C CG  1 
ATOM   11375 C  CD1 A TYR E 2 120 ? 105.621 146.102 90.779  0.50 43.89  ? 66  TYR C CD1 1 
ATOM   11376 C  CD1 B TYR E 2 120 ? 106.347 143.556 94.262  0.50 36.52  ? 66  TYR C CD1 1 
ATOM   11377 C  CD2 A TYR E 2 120 ? 105.168 143.817 91.272  0.50 41.36  ? 66  TYR C CD2 1 
ATOM   11378 C  CD2 B TYR E 2 120 ? 105.335 143.138 92.153  0.50 39.61  ? 66  TYR C CD2 1 
ATOM   11379 C  CE1 A TYR E 2 120 ? 104.535 146.144 89.928  0.50 44.13  ? 66  TYR C CE1 1 
ATOM   11380 C  CE1 B TYR E 2 120 ? 105.557 142.596 94.839  0.50 35.66  ? 66  TYR C CE1 1 
ATOM   11381 C  CE2 A TYR E 2 120 ? 104.077 143.849 90.425  0.50 45.25  ? 66  TYR C CE2 1 
ATOM   11382 C  CE2 B TYR E 2 120 ? 104.540 142.169 92.723  0.50 38.51  ? 66  TYR C CE2 1 
ATOM   11383 C  CZ  A TYR E 2 120 ? 103.761 145.018 89.759  0.50 46.77  ? 66  TYR C CZ  1 
ATOM   11384 C  CZ  B TYR E 2 120 ? 104.655 141.906 94.068  0.50 38.17  ? 66  TYR C CZ  1 
ATOM   11385 O  OH  A TYR E 2 120 ? 102.682 145.057 88.907  0.50 46.50  ? 66  TYR C OH  1 
ATOM   11386 O  OH  B TYR E 2 120 ? 103.872 140.941 94.650  0.50 41.07  ? 66  TYR C OH  1 
ATOM   11387 N  N   . TRP E 2 121 ? 109.365 145.324 89.717  1.00 35.49  ? 67  TRP C N   1 
ATOM   11388 C  CA  . TRP E 2 121 ? 109.808 146.378 88.815  1.00 33.66  ? 67  TRP C CA  1 
ATOM   11389 C  C   . TRP E 2 121 ? 109.271 146.082 87.429  1.00 40.11  ? 67  TRP C C   1 
ATOM   11390 O  O   . TRP E 2 121 ? 108.539 145.118 87.222  1.00 42.71  ? 67  TRP C O   1 
ATOM   11391 C  CB  . TRP E 2 121 ? 111.332 146.551 88.823  1.00 30.21  ? 67  TRP C CB  1 
ATOM   11392 C  CG  . TRP E 2 121 ? 112.112 145.446 88.204  1.00 32.97  ? 67  TRP C CG  1 
ATOM   11393 C  CD1 . TRP E 2 121 ? 112.524 145.359 86.912  1.00 34.02  ? 67  TRP C CD1 1 
ATOM   11394 C  CD2 . TRP E 2 121 ? 112.602 144.278 88.861  1.00 32.25  ? 67  TRP C CD2 1 
ATOM   11395 N  NE1 . TRP E 2 121 ? 113.223 144.203 86.719  1.00 34.25  ? 67  TRP C NE1 1 
ATOM   11396 C  CE2 . TRP E 2 121 ? 113.286 143.520 87.903  1.00 31.71  ? 67  TRP C CE2 1 
ATOM   11397 C  CE3 . TRP E 2 121 ? 112.517 143.796 90.166  1.00 31.59  ? 67  TRP C CE3 1 
ATOM   11398 C  CZ2 . TRP E 2 121 ? 113.884 142.309 88.206  1.00 32.34  ? 67  TRP C CZ2 1 
ATOM   11399 C  CZ3 . TRP E 2 121 ? 113.104 142.596 90.464  1.00 31.69  ? 67  TRP C CZ3 1 
ATOM   11400 C  CH2 . TRP E 2 121 ? 113.783 141.865 89.492  1.00 32.53  ? 67  TRP C CH2 1 
ATOM   11401 N  N   . ARG E 2 122 ? 109.605 146.937 86.475  1.00 42.98  ? 68  ARG C N   1 
ATOM   11402 C  CA  . ARG E 2 122 ? 109.125 146.780 85.114  1.00 42.53  ? 68  ARG C CA  1 
ATOM   11403 C  C   . ARG E 2 122 ? 110.303 146.846 84.165  1.00 45.10  ? 68  ARG C C   1 
ATOM   11404 O  O   . ARG E 2 122 ? 111.146 147.738 84.280  1.00 53.03  ? 68  ARG C O   1 
ATOM   11405 C  CB  . ARG E 2 122 ? 108.097 147.851 84.763  1.00 42.46  ? 68  ARG C CB  1 
ATOM   11406 C  CG  . ARG E 2 122 ? 107.604 147.771 83.343  1.00 47.86  ? 68  ARG C CG  1 
ATOM   11407 C  CD  . ARG E 2 122 ? 106.394 148.646 83.142  1.00 54.84  ? 68  ARG C CD  1 
ATOM   11408 N  NE  . ARG E 2 122 ? 106.032 148.736 81.735  1.00 72.71  ? 68  ARG C NE  1 
ATOM   11409 C  CZ  . ARG E 2 122 ? 104.963 149.370 81.280  1.00 80.82  ? 68  ARG C CZ  1 
ATOM   11410 N  NH1 . ARG E 2 122 ? 104.115 149.969 82.099  1.00 80.18  ? 68  ARG C NH1 1 
ATOM   11411 N  NH2 . ARG E 2 122 ? 104.737 149.400 79.971  1.00 81.01  ? 68  ARG C NH2 1 
ATOM   11412 N  N   . ASP E 2 123 ? 110.358 145.903 83.232  1.00 44.39  ? 69  ASP C N   1 
ATOM   11413 C  CA  . ASP E 2 123 ? 111.406 145.845 82.221  1.00 43.29  ? 69  ASP C CA  1 
ATOM   11414 C  C   . ASP E 2 123 ? 110.736 145.601 80.879  1.00 50.07  ? 69  ASP C C   1 
ATOM   11415 O  O   . ASP E 2 123 ? 110.307 144.480 80.595  1.00 57.26  ? 69  ASP C O   1 
ATOM   11416 C  CB  . ASP E 2 123 ? 112.414 144.747 82.544  1.00 38.61  ? 69  ASP C CB  1 
ATOM   11417 C  CG  . ASP E 2 123 ? 113.597 144.745 81.607  1.00 47.86  ? 69  ASP C CG  1 
ATOM   11418 O  OD1 . ASP E 2 123 ? 113.688 145.641 80.750  1.00 52.09  ? 69  ASP C OD1 1 
ATOM   11419 O  OD2 . ASP E 2 123 ? 114.443 143.838 81.724  1.00 52.77  ? 69  ASP C OD2 1 
ATOM   11420 N  N   . LYS E 2 124 ? 110.659 146.643 80.051  1.00 53.18  ? 70  LYS C N   1 
ATOM   11421 C  CA  . LYS E 2 124 ? 109.950 146.537 78.783  1.00 54.98  ? 70  LYS C CA  1 
ATOM   11422 C  C   . LYS E 2 124 ? 110.591 145.534 77.835  1.00 51.81  ? 70  LYS C C   1 
ATOM   11423 O  O   . LYS E 2 124 ? 109.945 145.116 76.870  1.00 54.97  ? 70  LYS C O   1 
ATOM   11424 C  CB  . LYS E 2 124 ? 109.871 147.902 78.112  1.00 60.49  ? 70  LYS C CB  1 
ATOM   11425 C  CG  . LYS E 2 124 ? 109.082 148.928 78.894  1.00 71.33  ? 70  LYS C CG  1 
ATOM   11426 C  CD  . LYS E 2 124 ? 109.009 150.250 78.147  1.00 79.06  ? 70  LYS C CD  1 
ATOM   11427 C  CE  . LYS E 2 124 ? 110.395 150.824 77.917  1.00 82.37  ? 70  LYS C CE  1 
ATOM   11428 N  NZ  . LYS E 2 124 ? 110.349 152.137 77.221  1.00 84.20  ? 70  LYS C NZ  1 
ATOM   11429 N  N   . ARG E 2 125 ? 111.840 145.136 78.080  1.00 48.83  ? 71  ARG C N   1 
ATOM   11430 C  CA  . ARG E 2 125 ? 112.449 144.102 77.257  1.00 47.12  ? 71  ARG C CA  1 
ATOM   11431 C  C   . ARG E 2 125 ? 111.775 142.750 77.443  1.00 53.15  ? 71  ARG C C   1 
ATOM   11432 O  O   . ARG E 2 125 ? 111.981 141.852 76.623  1.00 57.38  ? 71  ARG C O   1 
ATOM   11433 C  CB  . ARG E 2 125 ? 113.939 143.986 77.572  1.00 44.87  ? 71  ARG C CB  1 
ATOM   11434 C  CG  . ARG E 2 125 ? 114.756 145.180 77.126  1.00 49.58  ? 71  ARG C CG  1 
ATOM   11435 C  CD  . ARG E 2 125 ? 116.209 145.067 77.545  1.00 51.86  ? 71  ARG C CD  1 
ATOM   11436 N  NE  . ARG E 2 125 ? 116.368 145.071 78.993  1.00 50.45  ? 71  ARG C NE  1 
ATOM   11437 C  CZ  . ARG E 2 125 ? 117.536 145.070 79.618  1.00 48.89  ? 71  ARG C CZ  1 
ATOM   11438 N  NH1 . ARG E 2 125 ? 118.675 145.071 78.951  1.00 55.19  ? 71  ARG C NH1 1 
ATOM   11439 N  NH2 . ARG E 2 125 ? 117.561 145.070 80.945  1.00 45.29  ? 71  ARG C NH2 1 
ATOM   11440 N  N   . LEU E 2 126 ? 110.977 142.585 78.496  1.00 51.27  ? 72  LEU C N   1 
ATOM   11441 C  CA  . LEU E 2 126 ? 110.327 141.318 78.793  1.00 47.94  ? 72  LEU C CA  1 
ATOM   11442 C  C   . LEU E 2 126 ? 108.826 141.346 78.545  1.00 53.94  ? 72  LEU C C   1 
ATOM   11443 O  O   . LEU E 2 126 ? 108.120 140.439 78.991  1.00 57.42  ? 72  LEU C O   1 
ATOM   11444 C  CB  . LEU E 2 126 ? 110.610 140.910 80.237  1.00 41.53  ? 72  LEU C CB  1 
ATOM   11445 C  CG  . LEU E 2 126 ? 112.084 140.759 80.592  1.00 43.14  ? 72  LEU C CG  1 
ATOM   11446 C  CD1 . LEU E 2 126 ? 112.235 140.377 82.042  1.00 41.03  ? 72  LEU C CD1 1 
ATOM   11447 C  CD2 . LEU E 2 126 ? 112.736 139.730 79.696  1.00 49.89  ? 72  LEU C CD2 1 
ATOM   11448 N  N   . ALA E 2 127 ? 108.319 142.368 77.865  1.00 51.66  ? 73  ALA C N   1 
ATOM   11449 C  CA  . ALA E 2 127 ? 106.909 142.397 77.509  1.00 51.32  ? 73  ALA C CA  1 
ATOM   11450 C  C   . ALA E 2 127 ? 106.623 141.352 76.441  1.00 56.07  ? 73  ALA C C   1 
ATOM   11451 O  O   . ALA E 2 127 ? 107.355 141.244 75.455  1.00 60.59  ? 73  ALA C O   1 
ATOM   11452 C  CB  . ALA E 2 127 ? 106.521 143.785 77.010  1.00 50.17  ? 73  ALA C CB  1 
ATOM   11453 N  N   . TYR E 2 128 ? 105.560 140.577 76.635  1.00 56.06  ? 74  TYR C N   1 
ATOM   11454 C  CA  . TYR E 2 128 ? 105.174 139.549 75.682  1.00 57.66  ? 74  TYR C CA  1 
ATOM   11455 C  C   . TYR E 2 128 ? 103.679 139.631 75.420  1.00 64.40  ? 74  TYR C C   1 
ATOM   11456 O  O   . TYR E 2 128 ? 102.908 140.117 76.248  1.00 63.09  ? 74  TYR C O   1 
ATOM   11457 C  CB  . TYR E 2 128 ? 105.555 138.143 76.171  1.00 55.91  ? 74  TYR C CB  1 
ATOM   11458 C  CG  . TYR E 2 128 ? 104.861 137.698 77.434  1.00 58.43  ? 74  TYR C CG  1 
ATOM   11459 C  CD1 . TYR E 2 128 ? 105.418 137.943 78.676  1.00 56.37  ? 74  TYR C CD1 1 
ATOM   11460 C  CD2 . TYR E 2 128 ? 103.655 137.018 77.381  1.00 62.68  ? 74  TYR C CD2 1 
ATOM   11461 C  CE1 . TYR E 2 128 ? 104.793 137.537 79.828  1.00 55.71  ? 74  TYR C CE1 1 
ATOM   11462 C  CE2 . TYR E 2 128 ? 103.021 136.606 78.528  1.00 61.53  ? 74  TYR C CE2 1 
ATOM   11463 C  CZ  . TYR E 2 128 ? 103.594 136.868 79.748  1.00 58.41  ? 74  TYR C CZ  1 
ATOM   11464 O  OH  . TYR E 2 128 ? 102.960 136.455 80.893  1.00 58.53  ? 74  TYR C OH  1 
ATOM   11465 N  N   . SER E 2 129 ? 103.275 139.149 74.249  1.00 70.49  ? 75  SER C N   1 
ATOM   11466 C  CA  . SER E 2 129 ? 101.888 139.216 73.818  1.00 73.69  ? 75  SER C CA  1 
ATOM   11467 C  C   . SER E 2 129 ? 101.460 137.874 73.247  1.00 76.24  ? 75  SER C C   1 
ATOM   11468 O  O   . SER E 2 129 ? 102.283 137.066 72.812  1.00 74.97  ? 75  SER C O   1 
ATOM   11469 C  CB  . SER E 2 129 ? 101.674 140.322 72.781  1.00 75.19  ? 75  SER C CB  1 
ATOM   11470 O  OG  . SER E 2 129 ? 102.538 140.154 71.675  1.00 77.97  ? 75  SER C OG  1 
ATOM   11471 N  N   . GLY E 2 130 ? 100.148 137.646 73.256  1.00 77.31  ? 76  GLY C N   1 
ATOM   11472 C  CA  . GLY E 2 130 ? 99.581  136.398 72.803  1.00 81.73  ? 76  GLY C CA  1 
ATOM   11473 C  C   . GLY E 2 130 ? 99.395  135.351 73.877  1.00 84.33  ? 76  GLY C C   1 
ATOM   11474 O  O   . GLY E 2 130 ? 98.803  134.302 73.598  1.00 84.36  ? 76  GLY C O   1 
ATOM   11475 N  N   . ILE E 2 131 ? 99.889  135.590 75.086  1.00 81.08  ? 77  ILE C N   1 
ATOM   11476 C  CA  . ILE E 2 131 ? 99.706  134.655 76.192  1.00 76.93  ? 77  ILE C CA  1 
ATOM   11477 C  C   . ILE E 2 131 ? 99.023  135.386 77.341  1.00 76.29  ? 77  ILE C C   1 
ATOM   11478 O  O   . ILE E 2 131 ? 99.656  136.209 78.016  1.00 76.82  ? 77  ILE C O   1 
ATOM   11479 C  CB  . ILE E 2 131 ? 101.041 134.040 76.636  1.00 74.21  ? 77  ILE C CB  1 
ATOM   11480 C  CG1 . ILE E 2 131 ? 101.753 133.409 75.441  1.00 71.72  ? 77  ILE C CG1 1 
ATOM   11481 C  CG2 . ILE E 2 131 ? 100.807 132.998 77.707  1.00 69.71  ? 77  ILE C CG2 1 
ATOM   11482 C  CD1 . ILE E 2 131 ? 103.011 132.676 75.802  1.00 67.92  ? 77  ILE C CD1 1 
ATOM   11483 N  N   . PRO E 2 132 ? 97.746  135.136 77.590  1.00 76.96  ? 78  PRO C N   1 
ATOM   11484 C  CA  . PRO E 2 132 ? 97.039  135.824 78.683  1.00 75.67  ? 78  PRO C CA  1 
ATOM   11485 C  C   . PRO E 2 132 ? 97.250  135.143 80.032  1.00 75.86  ? 78  PRO C C   1 
ATOM   11486 O  O   . PRO E 2 132 ? 96.305  134.713 80.697  1.00 81.44  ? 78  PRO C O   1 
ATOM   11487 C  CB  . PRO E 2 132 ? 95.582  135.760 78.211  1.00 74.58  ? 78  PRO C CB  1 
ATOM   11488 C  CG  . PRO E 2 132 ? 95.508  134.472 77.472  1.00 75.71  ? 78  PRO C CG  1 
ATOM   11489 C  CD  . PRO E 2 132 ? 96.843  134.281 76.802  1.00 73.57  ? 78  PRO C CD  1 
ATOM   11490 N  N   . LEU E 2 133 ? 98.511  135.043 80.448  1.00 71.57  ? 79  LEU C N   1 
ATOM   11491 C  CA  . LEU E 2 133 ? 98.860  134.380 81.694  1.00 69.03  ? 79  LEU C CA  1 
ATOM   11492 C  C   . LEU E 2 133 ? 100.057 135.071 82.325  1.00 69.72  ? 79  LEU C C   1 
ATOM   11493 O  O   . LEU E 2 133 ? 100.881 135.668 81.631  1.00 68.08  ? 79  LEU C O   1 
ATOM   11494 C  CB  . LEU E 2 133 ? 99.194  132.903 81.467  1.00 67.05  ? 79  LEU C CB  1 
ATOM   11495 C  CG  . LEU E 2 133 ? 98.111  131.958 80.954  1.00 73.17  ? 79  LEU C CG  1 
ATOM   11496 C  CD1 . LEU E 2 133 ? 98.718  130.609 80.615  1.00 66.63  ? 79  LEU C CD1 1 
ATOM   11497 C  CD2 . LEU E 2 133 ? 97.011  131.805 81.984  1.00 80.13  ? 79  LEU C CD2 1 
ATOM   11498 N  N   . ASN E 2 134 ? 100.146 134.984 83.651  1.00 68.55  ? 80  ASN C N   1 
ATOM   11499 C  CA  . ASN E 2 134 ? 101.407 135.265 84.321  1.00 60.72  ? 80  ASN C CA  1 
ATOM   11500 C  C   . ASN E 2 134 ? 102.337 134.081 84.099  1.00 62.59  ? 80  ASN C C   1 
ATOM   11501 O  O   . ASN E 2 134 ? 101.946 132.932 84.314  1.00 68.12  ? 80  ASN C O   1 
ATOM   11502 C  CB  . ASN E 2 134 ? 101.224 135.472 85.826  1.00 64.09  ? 80  ASN C CB  1 
ATOM   11503 C  CG  . ASN E 2 134 ? 100.144 136.487 86.197  1.00 69.10  ? 80  ASN C CG  1 
ATOM   11504 O  OD1 . ASN E 2 134 ? 99.750  136.546 87.361  1.00 75.39  ? 80  ASN C OD1 1 
ATOM   11505 N  ND2 . ASN E 2 134 ? 99.666  137.273 85.244  1.00 66.10  ? 80  ASN C ND2 1 
ATOM   11506 N  N   . LEU E 2 135 ? 103.562 134.347 83.672  1.00 53.49  ? 81  LEU C N   1 
ATOM   11507 C  CA  . LEU E 2 135 ? 104.533 133.288 83.414  1.00 47.70  ? 81  LEU C CA  1 
ATOM   11508 C  C   . LEU E 2 135 ? 105.393 133.109 84.656  1.00 45.28  ? 81  LEU C C   1 
ATOM   11509 O  O   . LEU E 2 135 ? 106.309 133.892 84.903  1.00 51.35  ? 81  LEU C O   1 
ATOM   11510 C  CB  . LEU E 2 135 ? 105.392 133.612 82.198  1.00 46.27  ? 81  LEU C CB  1 
ATOM   11511 C  CG  . LEU E 2 135 ? 104.732 133.626 80.825  1.00 53.21  ? 81  LEU C CG  1 
ATOM   11512 C  CD1 . LEU E 2 135 ? 105.788 133.835 79.762  1.00 55.63  ? 81  LEU C CD1 1 
ATOM   11513 C  CD2 . LEU E 2 135 ? 103.975 132.338 80.584  1.00 50.54  ? 81  LEU C CD2 1 
ATOM   11514 N  N   . THR E 2 136 ? 105.098 132.085 85.446  1.00 39.61  ? 82  THR C N   1 
ATOM   11515 C  CA  . THR E 2 136 ? 105.962 131.701 86.555  1.00 40.44  ? 82  THR C CA  1 
ATOM   11516 C  C   . THR E 2 136 ? 107.052 130.807 85.987  1.00 41.45  ? 82  THR C C   1 
ATOM   11517 O  O   . THR E 2 136 ? 106.776 129.684 85.559  1.00 46.94  ? 82  THR C O   1 
ATOM   11518 C  CB  . THR E 2 136 ? 105.184 130.974 87.644  1.00 40.14  ? 82  THR C CB  1 
ATOM   11519 O  OG1 . THR E 2 136 ? 104.046 131.751 88.030  1.00 50.38  ? 82  THR C OG1 1 
ATOM   11520 C  CG2 . THR E 2 136 ? 106.064 130.748 88.851  1.00 32.86  ? 82  THR C CG2 1 
ATOM   11521 N  N   . LEU E 2 137 ? 108.284 131.299 85.963  1.00 41.79  ? 83  LEU C N   1 
ATOM   11522 C  CA  . LEU E 2 137 ? 109.363 130.523 85.376  1.00 42.53  ? 83  LEU C CA  1 
ATOM   11523 C  C   . LEU E 2 137 ? 110.184 129.840 86.461  1.00 48.31  ? 83  LEU C C   1 
ATOM   11524 O  O   . LEU E 2 137 ? 110.116 130.192 87.640  1.00 53.05  ? 83  LEU C O   1 
ATOM   11525 C  CB  . LEU E 2 137 ? 110.259 131.410 84.509  1.00 39.66  ? 83  LEU C CB  1 
ATOM   11526 C  CG  . LEU E 2 137 ? 109.543 132.143 83.374  1.00 41.08  ? 83  LEU C CG  1 
ATOM   11527 C  CD1 . LEU E 2 137 ? 110.468 133.142 82.733  1.00 44.84  ? 83  LEU C CD1 1 
ATOM   11528 C  CD2 . LEU E 2 137 ? 109.025 131.174 82.339  1.00 37.74  ? 83  LEU C CD2 1 
ATOM   11529 N  N   . ASP E 2 138 ? 110.951 128.838 86.046  1.00 43.34  ? 84  ASP C N   1 
ATOM   11530 C  CA  . ASP E 2 138 ? 111.893 128.199 86.951  1.00 44.07  ? 84  ASP C CA  1 
ATOM   11531 C  C   . ASP E 2 138 ? 112.858 129.245 87.492  1.00 52.74  ? 84  ASP C C   1 
ATOM   11532 O  O   . ASP E 2 138 ? 113.255 130.166 86.779  1.00 55.93  ? 84  ASP C O   1 
ATOM   11533 C  CB  . ASP E 2 138 ? 112.650 127.094 86.220  1.00 43.36  ? 84  ASP C CB  1 
ATOM   11534 C  CG  . ASP E 2 138 ? 113.534 126.284 87.139  1.00 57.95  ? 84  ASP C CG  1 
ATOM   11535 O  OD1 . ASP E 2 138 ? 113.458 126.480 88.368  1.00 63.11  ? 84  ASP C OD1 1 
ATOM   11536 O  OD2 . ASP E 2 138 ? 114.308 125.447 86.634  1.00 61.21  ? 84  ASP C OD2 1 
ATOM   11537 N  N   . ASN E 2 139 ? 113.216 129.123 88.773  1.00 51.44  ? 85  ASN C N   1 
ATOM   11538 C  CA  . ASN E 2 139 ? 113.947 130.210 89.418  1.00 48.09  ? 85  ASN C CA  1 
ATOM   11539 C  C   . ASN E 2 139 ? 115.332 130.423 88.825  1.00 53.84  ? 85  ASN C C   1 
ATOM   11540 O  O   . ASN E 2 139 ? 115.876 131.524 88.950  1.00 57.76  ? 85  ASN C O   1 
ATOM   11541 C  CB  . ASN E 2 139 ? 114.041 129.989 90.930  1.00 44.57  ? 85  ASN C CB  1 
ATOM   11542 C  CG  . ASN E 2 139 ? 114.754 128.716 91.299  1.00 50.75  ? 85  ASN C CG  1 
ATOM   11543 O  OD1 . ASN E 2 139 ? 115.950 128.723 91.574  1.00 52.72  ? 85  ASN C OD1 1 
ATOM   11544 N  ND2 . ASN E 2 139 ? 114.021 127.615 91.332  1.00 55.76  ? 85  ASN C ND2 1 
ATOM   11545 N  N   . ARG E 2 140 ? 115.903 129.419 88.156  1.00 52.79  ? 86  ARG C N   1 
ATOM   11546 C  CA  . ARG E 2 140 ? 117.209 129.603 87.533  1.00 54.34  ? 86  ARG C CA  1 
ATOM   11547 C  C   . ARG E 2 140 ? 117.183 130.667 86.444  1.00 56.18  ? 86  ARG C C   1 
ATOM   11548 O  O   . ARG E 2 140 ? 118.236 131.221 86.110  1.00 58.69  ? 86  ARG C O   1 
ATOM   11549 C  CB  . ARG E 2 140 ? 117.715 128.280 86.965  1.00 58.07  ? 86  ARG C CB  1 
ATOM   11550 C  CG  . ARG E 2 140 ? 118.138 127.288 88.035  1.00 63.35  ? 86  ARG C CG  1 
ATOM   11551 C  CD  . ARG E 2 140 ? 118.671 125.997 87.443  1.00 66.53  ? 86  ARG C CD  1 
ATOM   11552 N  NE  . ARG E 2 140 ? 117.624 125.217 86.798  1.00 68.12  ? 86  ARG C NE  1 
ATOM   11553 C  CZ  . ARG E 2 140 ? 117.791 123.995 86.313  1.00 69.52  ? 86  ARG C CZ  1 
ATOM   11554 N  NH1 . ARG E 2 140 ? 118.956 123.376 86.391  1.00 72.63  ? 86  ARG C NH1 1 
ATOM   11555 N  NH2 . ARG E 2 140 ? 116.765 123.382 85.734  1.00 67.30  ? 86  ARG C NH2 1 
ATOM   11556 N  N   . VAL E 2 141 ? 116.005 130.978 85.899  1.00 53.43  ? 87  VAL C N   1 
ATOM   11557 C  CA  . VAL E 2 141 ? 115.878 132.061 84.934  1.00 48.24  ? 87  VAL C CA  1 
ATOM   11558 C  C   . VAL E 2 141 ? 116.331 133.384 85.524  1.00 48.17  ? 87  VAL C C   1 
ATOM   11559 O  O   . VAL E 2 141 ? 116.733 134.284 84.783  1.00 49.00  ? 87  VAL C O   1 
ATOM   11560 C  CB  . VAL E 2 141 ? 114.425 132.142 84.422  1.00 44.96  ? 87  VAL C CB  1 
ATOM   11561 C  CG1 . VAL E 2 141 ? 114.255 133.259 83.419  1.00 40.35  ? 87  VAL C CG1 1 
ATOM   11562 C  CG2 . VAL E 2 141 ? 114.042 130.839 83.786  1.00 51.89  ? 87  VAL C CG2 1 
ATOM   11563 N  N   . ALA E 2 142 ? 116.303 133.522 86.851  1.00 49.11  ? 88  ALA C N   1 
ATOM   11564 C  CA  . ALA E 2 142 ? 116.788 134.750 87.464  1.00 45.52  ? 88  ALA C CA  1 
ATOM   11565 C  C   . ALA E 2 142 ? 118.251 135.007 87.143  1.00 47.83  ? 88  ALA C C   1 
ATOM   11566 O  O   . ALA E 2 142 ? 118.695 136.156 87.208  1.00 47.11  ? 88  ALA C O   1 
ATOM   11567 C  CB  . ALA E 2 142 ? 116.589 134.701 88.977  1.00 43.47  ? 88  ALA C CB  1 
ATOM   11568 N  N   . ASP E 2 143 ? 119.008 133.969 86.794  1.00 53.55  ? 89  ASP C N   1 
ATOM   11569 C  CA  . ASP E 2 143 ? 120.402 134.149 86.421  1.00 51.26  ? 89  ASP C CA  1 
ATOM   11570 C  C   . ASP E 2 143 ? 120.579 134.742 85.032  1.00 47.16  ? 89  ASP C C   1 
ATOM   11571 O  O   . ASP E 2 143 ? 121.690 135.155 84.693  1.00 48.76  ? 89  ASP C O   1 
ATOM   11572 C  CB  . ASP E 2 143 ? 121.144 132.816 86.502  1.00 54.56  ? 89  ASP C CB  1 
ATOM   11573 C  CG  . ASP E 2 143 ? 121.407 132.389 87.924  1.00 68.65  ? 89  ASP C CG  1 
ATOM   11574 O  OD1 . ASP E 2 143 ? 121.517 133.277 88.793  1.00 70.81  ? 89  ASP C OD1 1 
ATOM   11575 O  OD2 . ASP E 2 143 ? 121.506 131.172 88.176  1.00 76.07  ? 89  ASP C OD2 1 
ATOM   11576 N  N   . GLN E 2 144 ? 119.528 134.783 84.220  1.00 45.58  ? 90  GLN C N   1 
ATOM   11577 C  CA  . GLN E 2 144 ? 119.615 135.328 82.877  1.00 42.94  ? 90  GLN C CA  1 
ATOM   11578 C  C   . GLN E 2 144 ? 118.952 136.687 82.743  1.00 46.22  ? 90  GLN C C   1 
ATOM   11579 O  O   . GLN E 2 144 ? 118.907 137.227 81.636  1.00 50.17  ? 90  GLN C O   1 
ATOM   11580 C  CB  . GLN E 2 144 ? 118.991 134.361 81.872  1.00 45.84  ? 90  GLN C CB  1 
ATOM   11581 C  CG  . GLN E 2 144 ? 119.449 132.933 82.016  1.00 51.56  ? 90  GLN C CG  1 
ATOM   11582 C  CD  . GLN E 2 144 ? 118.571 131.981 81.242  1.00 63.52  ? 90  GLN C CD  1 
ATOM   11583 O  OE1 . GLN E 2 144 ? 117.833 131.190 81.823  1.00 63.75  ? 90  GLN C OE1 1 
ATOM   11584 N  NE2 . GLN E 2 144 ? 118.638 132.060 79.922  1.00 70.35  ? 90  GLN C NE2 1 
ATOM   11585 N  N   . LEU E 2 145 ? 118.440 137.251 83.831  1.00 46.45  ? 91  LEU C N   1 
ATOM   11586 C  CA  . LEU E 2 145 ? 117.759 138.534 83.820  1.00 41.54  ? 91  LEU C CA  1 
ATOM   11587 C  C   . LEU E 2 145 ? 118.507 139.524 84.696  1.00 43.44  ? 91  LEU C C   1 
ATOM   11588 O  O   . LEU E 2 145 ? 119.358 139.159 85.508  1.00 49.14  ? 91  LEU C O   1 
ATOM   11589 C  CB  . LEU E 2 145 ? 116.315 138.408 84.317  1.00 36.08  ? 91  LEU C CB  1 
ATOM   11590 C  CG  . LEU E 2 145 ? 115.401 137.362 83.699  1.00 36.78  ? 91  LEU C CG  1 
ATOM   11591 C  CD1 . LEU E 2 145 ? 114.073 137.383 84.403  1.00 35.27  ? 91  LEU C CD1 1 
ATOM   11592 C  CD2 . LEU E 2 145 ? 115.224 137.630 82.231  1.00 35.73  ? 91  LEU C CD2 1 
ATOM   11593 N  N   . TRP E 2 146 ? 118.174 140.796 84.523  1.00 41.44  ? 92  TRP C N   1 
ATOM   11594 C  CA  . TRP E 2 146 ? 118.666 141.831 85.414  1.00 39.00  ? 92  TRP C CA  1 
ATOM   11595 C  C   . TRP E 2 146 ? 117.818 141.857 86.677  1.00 40.24  ? 92  TRP C C   1 
ATOM   11596 O  O   . TRP E 2 146 ? 116.593 141.742 86.617  1.00 41.03  ? 92  TRP C O   1 
ATOM   11597 C  CB  . TRP E 2 146 ? 118.631 143.191 84.716  1.00 39.95  ? 92  TRP C CB  1 
ATOM   11598 C  CG  . TRP E 2 146 ? 119.106 144.328 85.555  1.00 40.68  ? 92  TRP C CG  1 
ATOM   11599 C  CD1 . TRP E 2 146 ? 120.369 144.824 85.617  1.00 40.82  ? 92  TRP C CD1 1 
ATOM   11600 C  CD2 . TRP E 2 146 ? 118.322 145.117 86.456  1.00 41.73  ? 92  TRP C CD2 1 
ATOM   11601 N  NE1 . TRP E 2 146 ? 120.425 145.869 86.501  1.00 40.56  ? 92  TRP C NE1 1 
ATOM   11602 C  CE2 . TRP E 2 146 ? 119.179 146.071 87.028  1.00 42.36  ? 92  TRP C CE2 1 
ATOM   11603 C  CE3 . TRP E 2 146 ? 116.979 145.110 86.833  1.00 36.59  ? 92  TRP C CE3 1 
ATOM   11604 C  CZ2 . TRP E 2 146 ? 118.739 147.005 87.957  1.00 40.91  ? 92  TRP C CZ2 1 
ATOM   11605 C  CZ3 . TRP E 2 146 ? 116.548 146.039 87.755  1.00 35.56  ? 92  TRP C CZ3 1 
ATOM   11606 C  CH2 . TRP E 2 146 ? 117.421 146.973 88.302  1.00 39.49  ? 92  TRP C CH2 1 
ATOM   11607 N  N   . VAL E 2 147 ? 118.477 141.974 87.824  1.00 36.00  ? 93  VAL C N   1 
ATOM   11608 C  CA  . VAL E 2 147 ? 117.782 142.122 89.100  1.00 33.53  ? 93  VAL C CA  1 
ATOM   11609 C  C   . VAL E 2 147 ? 118.432 143.265 89.869  1.00 34.13  ? 93  VAL C C   1 
ATOM   11610 O  O   . VAL E 2 147 ? 119.601 143.584 89.620  1.00 34.89  ? 93  VAL C O   1 
ATOM   11611 C  CB  . VAL E 2 147 ? 117.793 140.816 89.913  1.00 32.83  ? 93  VAL C CB  1 
ATOM   11612 C  CG1 . VAL E 2 147 ? 117.075 139.709 89.169  1.00 27.91  ? 93  VAL C CG1 1 
ATOM   11613 C  CG2 . VAL E 2 147 ? 119.205 140.405 90.256  1.00 34.31  ? 93  VAL C CG2 1 
ATOM   11614 N  N   . PRO E 2 148 ? 117.718 143.923 90.779  1.00 35.35  ? 94  PRO C N   1 
ATOM   11615 C  CA  . PRO E 2 148 ? 118.336 144.991 91.568  1.00 33.54  ? 94  PRO C CA  1 
ATOM   11616 C  C   . PRO E 2 148 ? 119.378 144.450 92.530  1.00 35.46  ? 94  PRO C C   1 
ATOM   11617 O  O   . PRO E 2 148 ? 119.300 143.313 92.995  1.00 40.88  ? 94  PRO C O   1 
ATOM   11618 C  CB  . PRO E 2 148 ? 117.154 145.603 92.327  1.00 32.61  ? 94  PRO C CB  1 
ATOM   11619 C  CG  . PRO E 2 148 ? 115.944 145.115 91.639  1.00 30.99  ? 94  PRO C CG  1 
ATOM   11620 C  CD  . PRO E 2 148 ? 116.289 143.785 91.085  1.00 34.07  ? 94  PRO C CD  1 
ATOM   11621 N  N   . ASP E 2 149 ? 120.356 145.293 92.835  1.00 32.57  ? 95  ASP C N   1 
ATOM   11622 C  CA  . ASP E 2 149 ? 121.421 144.946 93.774  1.00 29.46  ? 95  ASP C CA  1 
ATOM   11623 C  C   . ASP E 2 149 ? 121.092 145.464 95.173  1.00 29.74  ? 95  ASP C C   1 
ATOM   11624 O  O   . ASP E 2 149 ? 121.775 146.310 95.736  1.00 32.87  ? 95  ASP C O   1 
ATOM   11625 C  CB  . ASP E 2 149 ? 122.752 145.489 93.277  1.00 35.69  ? 95  ASP C CB  1 
ATOM   11626 C  CG  . ASP E 2 149 ? 122.700 146.961 93.000  1.00 43.54  ? 95  ASP C CG  1 
ATOM   11627 O  OD1 . ASP E 2 149 ? 121.582 147.486 92.839  1.00 42.79  ? 95  ASP C OD1 1 
ATOM   11628 O  OD2 . ASP E 2 149 ? 123.769 147.594 92.956  1.00 49.57  ? 95  ASP C OD2 1 
ATOM   11629 N  N   . THR E 2 150 ? 120.012 144.930 95.725  1.00 28.34  ? 96  THR C N   1 
ATOM   11630 C  CA  . THR E 2 150 ? 119.520 145.344 97.028  1.00 26.78  ? 96  THR C CA  1 
ATOM   11631 C  C   . THR E 2 150 ? 120.275 144.629 98.139  1.00 28.53  ? 96  THR C C   1 
ATOM   11632 O  O   . THR E 2 150 ? 120.609 143.451 98.016  1.00 35.82  ? 96  THR C O   1 
ATOM   11633 C  CB  . THR E 2 150 ? 118.024 145.054 97.123  1.00 26.87  ? 96  THR C CB  1 
ATOM   11634 O  OG1 . THR E 2 150 ? 117.339 145.764 96.089  1.00 26.24  ? 96  THR C OG1 1 
ATOM   11635 C  CG2 . THR E 2 150 ? 117.477 145.480 98.449  1.00 25.77  ? 96  THR C CG2 1 
ATOM   11636 N  N   . TYR E 2 151 ? 120.558 145.348 99.225  1.00 23.33  ? 97  TYR C N   1 
ATOM   11637 C  CA  . TYR E 2 151 ? 121.316 144.781 100.329 1.00 20.66  ? 97  TYR C CA  1 
ATOM   11638 C  C   . TYR E 2 151 ? 120.901 145.450 101.629 1.00 24.94  ? 97  TYR C C   1 
ATOM   11639 O  O   . TYR E 2 151 ? 120.273 146.510 101.634 1.00 28.92  ? 97  TYR C O   1 
ATOM   11640 C  CB  . TYR E 2 151 ? 122.826 144.912 100.095 1.00 26.35  ? 97  TYR C CB  1 
ATOM   11641 C  CG  . TYR E 2 151 ? 123.448 146.229 100.494 1.00 24.98  ? 97  TYR C CG  1 
ATOM   11642 C  CD1 . TYR E 2 151 ? 123.336 147.347 99.692  1.00 25.56  ? 97  TYR C CD1 1 
ATOM   11643 C  CD2 . TYR E 2 151 ? 124.180 146.338 101.660 1.00 26.90  ? 97  TYR C CD2 1 
ATOM   11644 C  CE1 . TYR E 2 151 ? 123.917 148.536 100.053 1.00 27.59  ? 97  TYR C CE1 1 
ATOM   11645 C  CE2 . TYR E 2 151 ? 124.761 147.520 102.024 1.00 28.39  ? 97  TYR C CE2 1 
ATOM   11646 C  CZ  . TYR E 2 151 ? 124.625 148.615 101.219 1.00 30.12  ? 97  TYR C CZ  1 
ATOM   11647 O  OH  . TYR E 2 151 ? 125.209 149.800 101.584 1.00 34.97  ? 97  TYR C OH  1 
ATOM   11648 N  N   . PHE E 2 152 ? 121.255 144.814 102.741 1.00 27.00  ? 98  PHE C N   1 
ATOM   11649 C  CA  . PHE E 2 152 ? 120.895 145.289 104.072 1.00 25.79  ? 98  PHE C CA  1 
ATOM   11650 C  C   . PHE E 2 152 ? 122.140 145.823 104.763 1.00 27.01  ? 98  PHE C C   1 
ATOM   11651 O  O   . PHE E 2 152 ? 123.054 145.056 105.070 1.00 33.25  ? 98  PHE C O   1 
ATOM   11652 C  CB  . PHE E 2 152 ? 120.259 144.167 104.891 1.00 25.41  ? 98  PHE C CB  1 
ATOM   11653 C  CG  . PHE E 2 152 ? 119.196 143.416 104.154 1.00 28.72  ? 98  PHE C CG  1 
ATOM   11654 C  CD1 . PHE E 2 152 ? 118.048 144.054 103.736 1.00 27.53  ? 98  PHE C CD1 1 
ATOM   11655 C  CD2 . PHE E 2 152 ? 119.344 142.079 103.866 1.00 30.86  ? 98  PHE C CD2 1 
ATOM   11656 C  CE1 . PHE E 2 152 ? 117.073 143.375 103.045 1.00 23.54  ? 98  PHE C CE1 1 
ATOM   11657 C  CE2 . PHE E 2 152 ? 118.369 141.399 103.175 1.00 26.61  ? 98  PHE C CE2 1 
ATOM   11658 C  CZ  . PHE E 2 152 ? 117.234 142.049 102.768 1.00 23.95  ? 98  PHE C CZ  1 
ATOM   11659 N  N   . LEU E 2 153 ? 122.166 147.132 105.027 1.00 26.85  ? 99  LEU C N   1 
ATOM   11660 C  CA  . LEU E 2 153 ? 123.378 147.753 105.555 1.00 26.95  ? 99  LEU C CA  1 
ATOM   11661 C  C   . LEU E 2 153 ? 123.741 147.208 106.922 1.00 32.51  ? 99  LEU C C   1 
ATOM   11662 O  O   . LEU E 2 153 ? 124.914 146.943 107.199 1.00 40.68  ? 99  LEU C O   1 
ATOM   11663 C  CB  . LEU E 2 153 ? 123.220 149.264 105.655 1.00 26.50  ? 99  LEU C CB  1 
ATOM   11664 C  CG  . LEU E 2 153 ? 123.093 150.072 104.381 1.00 33.32  ? 99  LEU C CG  1 
ATOM   11665 C  CD1 . LEU E 2 153 ? 121.649 150.377 104.169 1.00 36.76  ? 99  LEU C CD1 1 
ATOM   11666 C  CD2 . LEU E 2 153 ? 123.898 151.340 104.507 1.00 35.81  ? 99  LEU C CD2 1 
ATOM   11667 N  N   . ASN E 2 154 ? 122.756 147.057 107.804 1.00 28.92  ? 100 ASN C N   1 
ATOM   11668 C  CA  . ASN E 2 154 ? 123.032 146.698 109.186 1.00 27.42  ? 100 ASN C CA  1 
ATOM   11669 C  C   . ASN E 2 154 ? 122.985 145.200 109.431 1.00 27.59  ? 100 ASN C C   1 
ATOM   11670 O  O   . ASN E 2 154 ? 122.752 144.776 110.566 1.00 31.13  ? 100 ASN C O   1 
ATOM   11671 C  CB  . ASN E 2 154 ? 122.068 147.426 110.123 1.00 29.38  ? 100 ASN C CB  1 
ATOM   11672 C  CG  . ASN E 2 154 ? 120.650 146.972 109.962 1.00 32.19  ? 100 ASN C CG  1 
ATOM   11673 O  OD1 . ASN E 2 154 ? 120.199 146.700 108.857 1.00 33.59  ? 100 ASN C OD1 1 
ATOM   11674 N  ND2 . ASN E 2 154 ? 119.933 146.879 111.068 1.00 30.44  ? 100 ASN C ND2 1 
ATOM   11675 N  N   . ASP E 2 155 ? 123.213 144.382 108.414 1.00 27.62  ? 101 ASP C N   1 
ATOM   11676 C  CA  . ASP E 2 155 ? 123.238 142.946 108.630 1.00 29.28  ? 101 ASP C CA  1 
ATOM   11677 C  C   . ASP E 2 155 ? 124.658 142.476 108.911 1.00 31.22  ? 101 ASP C C   1 
ATOM   11678 O  O   . ASP E 2 155 ? 125.636 143.177 108.655 1.00 40.35  ? 101 ASP C O   1 
ATOM   11679 C  CB  . ASP E 2 155 ? 122.653 142.197 107.432 1.00 30.68  ? 101 ASP C CB  1 
ATOM   11680 C  CG  . ASP E 2 155 ? 123.632 142.043 106.292 1.00 41.83  ? 101 ASP C CG  1 
ATOM   11681 O  OD1 . ASP E 2 155 ? 124.516 142.904 106.122 1.00 51.00  ? 101 ASP C OD1 1 
ATOM   11682 O  OD2 . ASP E 2 155 ? 123.506 141.054 105.543 1.00 41.74  ? 101 ASP C OD2 1 
ATOM   11683 N  N   . LYS E 2 156 ? 124.755 141.278 109.463 1.00 28.00  ? 102 LYS C N   1 
ATOM   11684 C  CA  . LYS E 2 156 ? 126.021 140.657 109.809 1.00 29.72  ? 102 LYS C CA  1 
ATOM   11685 C  C   . LYS E 2 156 ? 126.220 139.310 109.146 1.00 34.68  ? 102 LYS C C   1 
ATOM   11686 O  O   . LYS E 2 156 ? 127.357 138.941 108.856 1.00 41.05  ? 102 LYS C O   1 
ATOM   11687 C  CB  . LYS E 2 156 ? 126.119 140.485 111.330 1.00 27.21  ? 102 LYS C CB  1 
ATOM   11688 C  CG  . LYS E 2 156 ? 125.519 141.644 112.088 1.00 29.23  ? 102 LYS C CG  1 
ATOM   11689 C  CD  . LYS E 2 156 ? 125.341 141.350 113.555 1.00 30.86  ? 102 LYS C CD  1 
ATOM   11690 C  CE  . LYS E 2 156 ? 126.654 141.379 114.286 1.00 28.79  ? 102 LYS C CE  1 
ATOM   11691 N  NZ  . LYS E 2 156 ? 126.464 141.368 115.754 1.00 31.73  ? 102 LYS C NZ  1 
ATOM   11692 N  N   . LYS E 2 157 ? 125.144 138.569 108.907 1.00 32.37  ? 103 LYS C N   1 
ATOM   11693 C  CA  . LYS E 2 157 ? 125.207 137.278 108.234 1.00 31.02  ? 103 LYS C CA  1 
ATOM   11694 C  C   . LYS E 2 157 ? 123.812 136.967 107.727 1.00 32.00  ? 103 LYS C C   1 
ATOM   11695 O  O   . LYS E 2 157 ? 122.890 136.815 108.531 1.00 36.70  ? 103 LYS C O   1 
ATOM   11696 C  CB  . LYS E 2 157 ? 125.690 136.189 109.187 1.00 33.57  ? 103 LYS C CB  1 
ATOM   11697 C  CG  . LYS E 2 157 ? 126.936 135.463 108.730 1.00 43.93  ? 103 LYS C CG  1 
ATOM   11698 C  CD  . LYS E 2 157 ? 126.764 134.894 107.337 1.00 49.51  ? 103 LYS C CD  1 
ATOM   11699 C  CE  . LYS E 2 157 ? 127.972 134.079 106.927 1.00 57.77  ? 103 LYS C CE  1 
ATOM   11700 N  NZ  . LYS E 2 157 ? 127.958 133.796 105.470 1.00 52.46  ? 103 LYS C NZ  1 
ATOM   11701 N  N   . SER E 2 158 ? 123.649 136.876 106.413 1.00 27.85  ? 104 SER C N   1 
ATOM   11702 C  CA  . SER E 2 158 ? 122.365 136.550 105.816 1.00 25.83  ? 104 SER C CA  1 
ATOM   11703 C  C   . SER E 2 158 ? 122.538 135.438 104.796 1.00 28.05  ? 104 SER C C   1 
ATOM   11704 O  O   . SER E 2 158 ? 123.585 135.315 104.161 1.00 38.77  ? 104 SER C O   1 
ATOM   11705 C  CB  . SER E 2 158 ? 121.724 137.762 105.135 1.00 27.86  ? 104 SER C CB  1 
ATOM   11706 O  OG  . SER E 2 158 ? 121.717 138.894 105.980 1.00 37.85  ? 104 SER C OG  1 
ATOM   11707 N  N   . PHE E 2 159 ? 121.497 134.630 104.638 1.00 26.55  ? 105 PHE C N   1 
ATOM   11708 C  CA  . PHE E 2 159 ? 121.511 133.605 103.611 1.00 25.32  ? 105 PHE C CA  1 
ATOM   11709 C  C   . PHE E 2 159 ? 120.123 133.476 103.011 1.00 23.28  ? 105 PHE C C   1 
ATOM   11710 O  O   . PHE E 2 159 ? 119.124 133.883 103.604 1.00 25.29  ? 105 PHE C O   1 
ATOM   11711 C  CB  . PHE E 2 159 ? 122.001 132.256 104.154 1.00 26.25  ? 105 PHE C CB  1 
ATOM   11712 C  CG  . PHE E 2 159 ? 121.066 131.604 105.130 1.00 25.02  ? 105 PHE C CG  1 
ATOM   11713 C  CD1 . PHE E 2 159 ? 121.123 131.906 106.474 1.00 26.51  ? 105 PHE C CD1 1 
ATOM   11714 C  CD2 . PHE E 2 159 ? 120.150 130.665 104.706 1.00 25.83  ? 105 PHE C CD2 1 
ATOM   11715 C  CE1 . PHE E 2 159 ? 120.273 131.301 107.366 1.00 25.37  ? 105 PHE C CE1 1 
ATOM   11716 C  CE2 . PHE E 2 159 ? 119.294 130.060 105.596 1.00 26.09  ? 105 PHE C CE2 1 
ATOM   11717 C  CZ  . PHE E 2 159 ? 119.358 130.375 106.926 1.00 25.63  ? 105 PHE C CZ  1 
ATOM   11718 N  N   . VAL E 2 160 ? 120.081 132.913 101.810 1.00 23.76  ? 106 VAL C N   1 
ATOM   11719 C  CA  . VAL E 2 160 ? 118.844 132.576 101.121 1.00 25.28  ? 106 VAL C CA  1 
ATOM   11720 C  C   . VAL E 2 160 ? 118.668 131.069 101.213 1.00 29.86  ? 106 VAL C C   1 
ATOM   11721 O  O   . VAL E 2 160 ? 119.586 130.311 100.880 1.00 37.65  ? 106 VAL C O   1 
ATOM   11722 C  CB  . VAL E 2 160 ? 118.872 133.046 99.656  1.00 26.24  ? 106 VAL C CB  1 
ATOM   11723 C  CG1 . VAL E 2 160 ? 117.618 132.625 98.935  1.00 23.01  ? 106 VAL C CG1 1 
ATOM   11724 C  CG2 . VAL E 2 160 ? 119.032 134.543 99.587  1.00 23.99  ? 106 VAL C CG2 1 
ATOM   11725 N  N   . HIS E 2 161 ? 117.499 130.636 101.674 1.00 22.41  ? 107 HIS C N   1 
ATOM   11726 C  CA  . HIS E 2 161 ? 117.259 129.216 101.892 1.00 24.49  ? 107 HIS C CA  1 
ATOM   11727 C  C   . HIS E 2 161 ? 117.352 128.450 100.580 1.00 31.43  ? 107 HIS C C   1 
ATOM   11728 O  O   . HIS E 2 161 ? 116.970 128.953 99.522  1.00 34.97  ? 107 HIS C O   1 
ATOM   11729 C  CB  . HIS E 2 161 ? 115.889 129.009 102.530 1.00 23.76  ? 107 HIS C CB  1 
ATOM   11730 C  CG  . HIS E 2 161 ? 115.742 129.662 103.869 1.00 27.62  ? 107 HIS C CG  1 
ATOM   11731 N  ND1 . HIS E 2 161 ? 115.348 128.972 104.993 1.00 31.41  ? 107 HIS C ND1 1 
ATOM   11732 C  CD2 . HIS E 2 161 ? 115.942 130.938 104.264 1.00 25.58  ? 107 HIS C CD2 1 
ATOM   11733 C  CE1 . HIS E 2 161 ? 115.312 129.796 106.023 1.00 23.70  ? 107 HIS C CE1 1 
ATOM   11734 N  NE2 . HIS E 2 161 ? 115.664 130.997 105.606 1.00 21.65  ? 107 HIS C NE2 1 
ATOM   11735 N  N   . GLY E 2 162 ? 117.866 127.226 100.650 1.00 25.91  ? 108 GLY C N   1 
ATOM   11736 C  CA  . GLY E 2 162 ? 118.126 126.461 99.448  1.00 25.20  ? 108 GLY C CA  1 
ATOM   11737 C  C   . GLY E 2 162 ? 117.721 125.003 99.486  1.00 27.94  ? 108 GLY C C   1 
ATOM   11738 O  O   . GLY E 2 162 ? 118.317 124.176 98.795  1.00 30.44  ? 108 GLY C O   1 
ATOM   11739 N  N   . VAL E 2 163 ? 116.708 124.669 100.279 1.00 26.32  ? 109 VAL C N   1 
ATOM   11740 C  CA  . VAL E 2 163 ? 116.126 123.332 100.307 1.00 24.23  ? 109 VAL C CA  1 
ATOM   11741 C  C   . VAL E 2 163 ? 114.629 123.476 100.080 1.00 26.68  ? 109 VAL C C   1 
ATOM   11742 O  O   . VAL E 2 163 ? 113.976 124.264 100.768 1.00 29.56  ? 109 VAL C O   1 
ATOM   11743 C  CB  . VAL E 2 163 ? 116.417 122.613 101.639 1.00 22.15  ? 109 VAL C CB  1 
ATOM   11744 C  CG1 . VAL E 2 163 ? 115.466 121.467 101.843 1.00 20.77  ? 109 VAL C CG1 1 
ATOM   11745 C  CG2 . VAL E 2 163 ? 117.842 122.110 101.667 1.00 27.49  ? 109 VAL C CG2 1 
ATOM   11746 N  N   . THR E 2 164 ? 114.081 122.722 99.125  1.00 28.22  ? 110 THR C N   1 
ATOM   11747 C  CA  . THR E 2 164 ? 114.802 121.721 98.348  1.00 25.91  ? 110 THR C CA  1 
ATOM   11748 C  C   . THR E 2 164 ? 115.499 122.303 97.123  1.00 29.19  ? 110 THR C C   1 
ATOM   11749 O  O   . THR E 2 164 ? 116.338 121.649 96.514  1.00 36.17  ? 110 THR C O   1 
ATOM   11750 C  CB  . THR E 2 164 ? 113.859 120.599 97.895  1.00 27.23  ? 110 THR C CB  1 
ATOM   11751 O  OG1 . THR E 2 164 ? 112.986 121.087 96.872  1.00 30.14  ? 110 THR C OG1 1 
ATOM   11752 C  CG2 . THR E 2 164 ? 113.020 120.116 99.057  1.00 25.08  ? 110 THR C CG2 1 
ATOM   11753 N  N   . VAL E 2 165 ? 115.142 123.533 96.762  1.00 27.56  ? 111 VAL C N   1 
ATOM   11754 C  CA  . VAL E 2 165 ? 115.855 124.314 95.762  1.00 29.60  ? 111 VAL C CA  1 
ATOM   11755 C  C   . VAL E 2 165 ? 116.069 125.706 96.335  1.00 31.03  ? 111 VAL C C   1 
ATOM   11756 O  O   . VAL E 2 165 ? 115.590 126.031 97.419  1.00 34.44  ? 111 VAL C O   1 
ATOM   11757 C  CB  . VAL E 2 165 ? 115.108 124.396 94.416  1.00 28.13  ? 111 VAL C CB  1 
ATOM   11758 C  CG1 . VAL E 2 165 ? 114.955 123.029 93.801  1.00 27.00  ? 111 VAL C CG1 1 
ATOM   11759 C  CG2 . VAL E 2 165 ? 113.766 125.044 94.606  1.00 26.43  ? 111 VAL C CG2 1 
ATOM   11760 N  N   . LYS E 2 166 ? 116.796 126.533 95.596  1.00 30.08  ? 112 LYS C N   1 
ATOM   11761 C  CA  . LYS E 2 166 ? 117.001 127.904 96.039  1.00 31.82  ? 112 LYS C CA  1 
ATOM   11762 C  C   . LYS E 2 166 ? 115.659 128.612 96.130  1.00 36.71  ? 112 LYS C C   1 
ATOM   11763 O  O   . LYS E 2 166 ? 114.932 128.713 95.140  1.00 39.09  ? 112 LYS C O   1 
ATOM   11764 C  CB  . LYS E 2 166 ? 117.935 128.639 95.084  1.00 34.57  ? 112 LYS C CB  1 
ATOM   11765 C  CG  . LYS E 2 166 ? 118.450 129.955 95.619  1.00 40.05  ? 112 LYS C CG  1 
ATOM   11766 C  CD  . LYS E 2 166 ? 119.626 130.442 94.803  1.00 57.71  ? 112 LYS C CD  1 
ATOM   11767 C  CE  . LYS E 2 166 ? 120.345 131.593 95.483  1.00 58.81  ? 112 LYS C CE  1 
ATOM   11768 N  NZ  . LYS E 2 166 ? 119.544 132.842 95.475  1.00 51.99  ? 112 LYS C NZ  1 
ATOM   11769 N  N   . ASN E 2 167 ? 115.331 129.105 97.321  1.00 33.66  ? 113 ASN C N   1 
ATOM   11770 C  CA  . ASN E 2 167 ? 114.005 129.655 97.593  1.00 26.07  ? 113 ASN C CA  1 
ATOM   11771 C  C   . ASN E 2 167 ? 113.879 130.992 96.873  1.00 30.26  ? 113 ASN C C   1 
ATOM   11772 O  O   . ASN E 2 167 ? 114.074 132.068 97.438  1.00 34.03  ? 113 ASN C O   1 
ATOM   11773 C  CB  . ASN E 2 167 ? 113.782 129.794 99.091  1.00 23.66  ? 113 ASN C CB  1 
ATOM   11774 C  CG  . ASN E 2 167 ? 113.523 128.464 99.766  1.00 25.56  ? 113 ASN C CG  1 
ATOM   11775 O  OD1 . ASN E 2 167 ? 112.822 128.394 100.762 1.00 30.42  ? 113 ASN C OD1 1 
ATOM   11776 N  ND2 . ASN E 2 167 ? 114.075 127.403 99.217  1.00 23.29  ? 113 ASN C ND2 1 
ATOM   11777 N  N   . ARG E 2 168 ? 113.539 130.911 95.591  1.00 31.25  ? 114 ARG C N   1 
ATOM   11778 C  CA  . ARG E 2 168 ? 113.501 132.061 94.707  1.00 30.15  ? 114 ARG C CA  1 
ATOM   11779 C  C   . ARG E 2 168 ? 112.311 131.929 93.771  1.00 37.90  ? 114 ARG C C   1 
ATOM   11780 O  O   . ARG E 2 168 ? 111.906 130.823 93.413  1.00 45.11  ? 114 ARG C O   1 
ATOM   11781 C  CB  . ARG E 2 168 ? 114.807 132.171 93.918  1.00 32.59  ? 114 ARG C CB  1 
ATOM   11782 C  CG  . ARG E 2 168 ? 114.985 133.441 93.132  1.00 37.09  ? 114 ARG C CG  1 
ATOM   11783 C  CD  . ARG E 2 168 ? 116.426 133.586 92.709  1.00 45.56  ? 114 ARG C CD  1 
ATOM   11784 N  NE  . ARG E 2 168 ? 116.894 132.398 92.011  1.00 55.66  ? 114 ARG C NE  1 
ATOM   11785 C  CZ  . ARG E 2 168 ? 118.146 132.200 91.630  1.00 55.95  ? 114 ARG C CZ  1 
ATOM   11786 N  NH1 . ARG E 2 168 ? 119.088 133.093 91.867  1.00 54.48  ? 114 ARG C NH1 1 
ATOM   11787 N  NH2 . ARG E 2 168 ? 118.460 131.077 90.993  1.00 56.44  ? 114 ARG C NH2 1 
ATOM   11788 N  N   . MET E 2 169 ? 111.747 133.068 93.383  1.00 36.58  ? 115 MET C N   1 
ATOM   11789 C  CA  . MET E 2 169 ? 110.579 133.091 92.513  1.00 31.07  ? 115 MET C CA  1 
ATOM   11790 C  C   . MET E 2 169 ? 110.741 134.173 91.461  1.00 34.99  ? 115 MET C C   1 
ATOM   11791 O  O   . MET E 2 169 ? 111.063 135.314 91.798  1.00 37.06  ? 115 MET C O   1 
ATOM   11792 C  CB  . MET E 2 169 ? 109.302 133.342 93.314  1.00 30.55  ? 115 MET C CB  1 
ATOM   11793 C  CG  . MET E 2 169 ? 108.118 133.730 92.456  1.00 36.44  ? 115 MET C CG  1 
ATOM   11794 S  SD  . MET E 2 169 ? 106.629 134.026 93.408  1.00 61.63  ? 115 MET C SD  1 
ATOM   11795 C  CE  . MET E 2 169 ? 107.086 135.517 94.272  1.00 40.69  ? 115 MET C CE  1 
ATOM   11796 N  N   . ILE E 2 170 ? 110.505 133.820 90.199  1.00 37.62  ? 116 ILE C N   1 
ATOM   11797 C  CA  . ILE E 2 170 ? 110.477 134.764 89.086  1.00 35.26  ? 116 ILE C CA  1 
ATOM   11798 C  C   . ILE E 2 170 ? 109.131 134.631 88.394  1.00 36.71  ? 116 ILE C C   1 
ATOM   11799 O  O   . ILE E 2 170 ? 108.798 133.557 87.872  1.00 45.13  ? 116 ILE C O   1 
ATOM   11800 C  CB  . ILE E 2 170 ? 111.620 134.517 88.092  1.00 35.05  ? 116 ILE C CB  1 
ATOM   11801 C  CG1 . ILE E 2 170 ? 112.926 135.083 88.630  1.00 39.99  ? 116 ILE C CG1 1 
ATOM   11802 C  CG2 . ILE E 2 170 ? 111.313 135.153 86.756  1.00 35.80  ? 116 ILE C CG2 1 
ATOM   11803 C  CD1 . ILE E 2 170 ? 113.045 136.576 88.470  1.00 35.85  ? 116 ILE C CD1 1 
ATOM   11804 N  N   . ARG E 2 171 ? 108.360 135.715 88.388  1.00 32.62  ? 117 ARG C N   1 
ATOM   11805 C  CA  . ARG E 2 171 ? 107.064 135.740 87.726  1.00 34.45  ? 117 ARG C CA  1 
ATOM   11806 C  C   . ARG E 2 171 ? 107.029 136.926 86.779  1.00 37.94  ? 117 ARG C C   1 
ATOM   11807 O  O   . ARG E 2 171 ? 107.292 138.061 87.190  1.00 44.09  ? 117 ARG C O   1 
ATOM   11808 C  CB  . ARG E 2 171 ? 105.924 135.821 88.742  1.00 37.12  ? 117 ARG C CB  1 
ATOM   11809 C  CG  . ARG E 2 171 ? 104.545 135.630 88.142  1.00 44.66  ? 117 ARG C CG  1 
ATOM   11810 C  CD  . ARG E 2 171 ? 103.470 135.648 89.211  1.00 46.05  ? 117 ARG C CD  1 
ATOM   11811 N  NE  . ARG E 2 171 ? 103.615 134.541 90.146  1.00 45.61  ? 117 ARG C NE  1 
ATOM   11812 C  CZ  . ARG E 2 171 ? 102.997 134.464 91.314  1.00 41.80  ? 117 ARG C CZ  1 
ATOM   11813 N  NH1 . ARG E 2 171 ? 102.197 135.428 91.735  1.00 43.14  ? 117 ARG C NH1 1 
ATOM   11814 N  NH2 . ARG E 2 171 ? 103.193 133.399 92.082  1.00 35.79  ? 117 ARG C NH2 1 
ATOM   11815 N  N   . LEU E 2 172 ? 106.724 136.663 85.516  1.00 38.61  ? 118 LEU C N   1 
ATOM   11816 C  CA  . LEU E 2 172 ? 106.610 137.693 84.499  1.00 41.66  ? 118 LEU C CA  1 
ATOM   11817 C  C   . LEU E 2 172 ? 105.144 137.962 84.208  1.00 47.35  ? 118 LEU C C   1 
ATOM   11818 O  O   . LEU E 2 172 ? 104.301 137.073 84.315  1.00 54.35  ? 118 LEU C O   1 
ATOM   11819 C  CB  . LEU E 2 172 ? 107.319 137.281 83.209  1.00 43.51  ? 118 LEU C CB  1 
ATOM   11820 C  CG  . LEU E 2 172 ? 108.784 136.872 83.301  1.00 45.44  ? 118 LEU C CG  1 
ATOM   11821 C  CD1 . LEU E 2 172 ? 109.327 136.589 81.922  1.00 41.91  ? 118 LEU C CD1 1 
ATOM   11822 C  CD2 . LEU E 2 172 ? 109.592 137.952 83.980  1.00 46.05  ? 118 LEU C CD2 1 
ATOM   11823 N  N   . HIS E 2 173 ? 104.850 139.194 83.833  1.00 46.93  ? 119 HIS C N   1 
ATOM   11824 C  CA  . HIS E 2 173 ? 103.514 139.621 83.465  1.00 47.09  ? 119 HIS C CA  1 
ATOM   11825 C  C   . HIS E 2 173 ? 103.552 140.178 82.051  1.00 52.62  ? 119 HIS C C   1 
ATOM   11826 O  O   . HIS E 2 173 ? 104.610 140.603 81.575  1.00 56.17  ? 119 HIS C O   1 
ATOM   11827 C  CB  . HIS E 2 173 ? 102.986 140.676 84.444  1.00 46.34  ? 119 HIS C CB  1 
ATOM   11828 C  CG  . HIS E 2 173 ? 103.063 140.260 85.879  1.00 50.30  ? 119 HIS C CG  1 
ATOM   11829 N  ND1 . HIS E 2 173 ? 104.258 140.094 86.543  1.00 45.23  ? 119 HIS C ND1 1 
ATOM   11830 C  CD2 . HIS E 2 173 ? 102.093 139.987 86.781  1.00 52.57  ? 119 HIS C CD2 1 
ATOM   11831 C  CE1 . HIS E 2 173 ? 104.022 139.730 87.790  1.00 42.85  ? 119 HIS C CE1 1 
ATOM   11832 N  NE2 . HIS E 2 173 ? 102.716 139.658 87.960  1.00 48.51  ? 119 HIS C NE2 1 
ATOM   11833 N  N   . PRO E 2 174 ? 102.421 140.179 81.340  1.00 56.26  ? 120 PRO C N   1 
ATOM   11834 C  CA  . PRO E 2 174 ? 102.454 140.532 79.912  1.00 53.86  ? 120 PRO C CA  1 
ATOM   11835 C  C   . PRO E 2 174 ? 102.946 141.936 79.616  1.00 56.26  ? 120 PRO C C   1 
ATOM   11836 O  O   . PRO E 2 174 ? 103.374 142.191 78.487  1.00 60.55  ? 120 PRO C O   1 
ATOM   11837 C  CB  . PRO E 2 174 ? 100.995 140.352 79.477  1.00 54.05  ? 120 PRO C CB  1 
ATOM   11838 C  CG  . PRO E 2 174 ? 100.436 139.387 80.445  1.00 57.21  ? 120 PRO C CG  1 
ATOM   11839 C  CD  . PRO E 2 174 ? 101.093 139.695 81.747  1.00 60.96  ? 120 PRO C CD  1 
ATOM   11840 N  N   . ASP E 2 175 ? 102.911 142.854 80.575  1.00 57.65  ? 121 ASP C N   1 
ATOM   11841 C  CA  . ASP E 2 175 ? 103.344 144.221 80.325  1.00 57.96  ? 121 ASP C CA  1 
ATOM   11842 C  C   . ASP E 2 175 ? 104.824 144.441 80.595  1.00 61.34  ? 121 ASP C C   1 
ATOM   11843 O  O   . ASP E 2 175 ? 105.294 145.577 80.495  1.00 65.03  ? 121 ASP C O   1 
ATOM   11844 C  CB  . ASP E 2 175 ? 102.532 145.196 81.172  1.00 60.51  ? 121 ASP C CB  1 
ATOM   11845 C  CG  . ASP E 2 175 ? 102.838 145.073 82.645  1.00 64.77  ? 121 ASP C CG  1 
ATOM   11846 O  OD1 . ASP E 2 175 ? 102.946 143.935 83.140  1.00 65.53  ? 121 ASP C OD1 1 
ATOM   11847 O  OD2 . ASP E 2 175 ? 102.973 146.119 83.310  1.00 67.78  ? 121 ASP C OD2 1 
ATOM   11848 N  N   . GLY E 2 176 ? 105.567 143.394 80.930  1.00 59.96  ? 122 GLY C N   1 
ATOM   11849 C  CA  . GLY E 2 176 ? 106.968 143.523 81.254  1.00 52.95  ? 122 GLY C CA  1 
ATOM   11850 C  C   . GLY E 2 176 ? 107.284 143.647 82.724  1.00 49.22  ? 122 GLY C C   1 
ATOM   11851 O  O   . GLY E 2 176 ? 108.453 143.825 83.073  1.00 55.21  ? 122 GLY C O   1 
ATOM   11852 N  N   . THR E 2 177 ? 106.289 143.545 83.594  1.00 45.40  ? 123 THR C N   1 
ATOM   11853 C  CA  . THR E 2 177 ? 106.517 143.626 85.027  1.00 45.81  ? 123 THR C CA  1 
ATOM   11854 C  C   . THR E 2 177 ? 107.116 142.330 85.554  1.00 43.39  ? 123 THR C C   1 
ATOM   11855 O  O   . THR E 2 177 ? 106.634 141.241 85.239  1.00 46.90  ? 123 THR C O   1 
ATOM   11856 C  CB  . THR E 2 177 ? 105.210 143.914 85.749  1.00 47.01  ? 123 THR C CB  1 
ATOM   11857 O  OG1 . THR E 2 177 ? 104.703 145.185 85.335  1.00 57.37  ? 123 THR C OG1 1 
ATOM   11858 C  CG2 . THR E 2 177 ? 105.448 143.935 87.223  1.00 40.32  ? 123 THR C CG2 1 
ATOM   11859 N  N   . VAL E 2 178 ? 108.155 142.453 86.372  1.00 41.49  ? 124 VAL C N   1 
ATOM   11860 C  CA  . VAL E 2 178 ? 108.831 141.321 86.988  1.00 38.51  ? 124 VAL C CA  1 
ATOM   11861 C  C   . VAL E 2 178 ? 108.574 141.351 88.486  1.00 38.48  ? 124 VAL C C   1 
ATOM   11862 O  O   . VAL E 2 178 ? 108.783 142.385 89.142  1.00 43.54  ? 124 VAL C O   1 
ATOM   11863 C  CB  . VAL E 2 178 ? 110.339 141.341 86.696  1.00 35.24  ? 124 VAL C CB  1 
ATOM   11864 C  CG1 . VAL E 2 178 ? 111.001 140.117 87.287  1.00 33.56  ? 124 VAL C CG1 1 
ATOM   11865 C  CG2 . VAL E 2 178 ? 110.580 141.405 85.212  1.00 35.42  ? 124 VAL C CG2 1 
ATOM   11866 N  N   . LEU E 2 179 ? 108.115 140.218 89.017  1.00 33.84  ? 125 LEU C N   1 
ATOM   11867 C  CA  . LEU E 2 179 ? 108.029 139.971 90.450  1.00 31.36  ? 125 LEU C CA  1 
ATOM   11868 C  C   . LEU E 2 179 ? 109.107 138.964 90.826  1.00 31.53  ? 125 LEU C C   1 
ATOM   11869 O  O   . LEU E 2 179 ? 109.132 137.847 90.295  1.00 39.50  ? 125 LEU C O   1 
ATOM   11870 C  CB  . LEU E 2 179 ? 106.647 139.452 90.837  1.00 34.70  ? 125 LEU C CB  1 
ATOM   11871 C  CG  . LEU E 2 179 ? 106.578 138.699 92.166  1.00 37.46  ? 125 LEU C CG  1 
ATOM   11872 C  CD1 . LEU E 2 179 ? 106.915 139.593 93.335  1.00 37.43  ? 125 LEU C CD1 1 
ATOM   11873 C  CD2 . LEU E 2 179 ? 105.215 138.076 92.359  1.00 35.54  ? 125 LEU C CD2 1 
ATOM   11874 N  N   . TYR E 2 180 ? 109.975 139.356 91.754  1.00 27.91  ? 126 TYR C N   1 
ATOM   11875 C  CA  . TYR E 2 180 ? 111.168 138.601 92.120  1.00 29.24  ? 126 TYR C CA  1 
ATOM   11876 C  C   . TYR E 2 180 ? 111.148 138.397 93.627  1.00 32.41  ? 126 TYR C C   1 
ATOM   11877 O  O   . TYR E 2 180 ? 111.298 139.355 94.386  1.00 37.27  ? 126 TYR C O   1 
ATOM   11878 C  CB  . TYR E 2 180 ? 112.421 139.353 91.673  1.00 29.40  ? 126 TYR C CB  1 
ATOM   11879 C  CG  . TYR E 2 180 ? 113.746 138.738 92.048  1.00 29.74  ? 126 TYR C CG  1 
ATOM   11880 C  CD1 . TYR E 2 180 ? 114.074 137.453 91.662  1.00 30.01  ? 126 TYR C CD1 1 
ATOM   11881 C  CD2 . TYR E 2 180 ? 114.685 139.463 92.756  1.00 29.59  ? 126 TYR C CD2 1 
ATOM   11882 C  CE1 . TYR E 2 180 ? 115.288 136.904 91.988  1.00 32.63  ? 126 TYR C CE1 1 
ATOM   11883 C  CE2 . TYR E 2 180 ? 115.897 138.922 93.082  1.00 30.13  ? 126 TYR C CE2 1 
ATOM   11884 C  CZ  . TYR E 2 180 ? 116.193 137.642 92.702  1.00 30.96  ? 126 TYR C CZ  1 
ATOM   11885 O  OH  . TYR E 2 180 ? 117.409 137.099 93.028  1.00 36.29  ? 126 TYR C OH  1 
ATOM   11886 N  N   . GLY E 2 181 ? 110.958 137.165 94.061  1.00 29.23  ? 127 GLY C N   1 
ATOM   11887 C  CA  . GLY E 2 181 ? 110.786 136.859 95.474  1.00 24.71  ? 127 GLY C CA  1 
ATOM   11888 C  C   . GLY E 2 181 ? 111.913 136.005 96.018  1.00 27.16  ? 127 GLY C C   1 
ATOM   11889 O  O   . GLY E 2 181 ? 112.415 135.123 95.326  1.00 35.20  ? 127 GLY C O   1 
ATOM   11890 N  N   . LEU E 2 182 ? 112.291 136.265 97.267  1.00 24.80  ? 128 LEU C N   1 
ATOM   11891 C  CA  . LEU E 2 182 ? 113.311 135.488 97.957  1.00 21.66  ? 128 LEU C CA  1 
ATOM   11892 C  C   . LEU E 2 182 ? 112.838 135.186 99.371  1.00 24.21  ? 128 LEU C C   1 
ATOM   11893 O  O   . LEU E 2 182 ? 112.016 135.905 99.930  1.00 33.26  ? 128 LEU C O   1 
ATOM   11894 C  CB  . LEU E 2 182 ? 114.646 136.240 98.004  1.00 22.20  ? 128 LEU C CB  1 
ATOM   11895 C  CG  . LEU E 2 182 ? 115.358 136.524 96.685  1.00 22.49  ? 128 LEU C CG  1 
ATOM   11896 C  CD1 . LEU E 2 182 ? 116.308 137.680 96.829  1.00 18.01  ? 128 LEU C CD1 1 
ATOM   11897 C  CD2 . LEU E 2 182 ? 116.115 135.307 96.226  1.00 30.98  ? 128 LEU C CD2 1 
ATOM   11898 N  N   . ARG E 2 183 ? 113.360 134.115 99.956  1.00 21.63  ? 129 ARG C N   1 
ATOM   11899 C  CA  . ARG E 2 183 ? 113.142 133.821 101.368 1.00 22.90  ? 129 ARG C CA  1 
ATOM   11900 C  C   . ARG E 2 183 ? 114.478 133.918 102.080 1.00 22.74  ? 129 ARG C C   1 
ATOM   11901 O  O   . ARG E 2 183 ? 115.390 133.142 101.791 1.00 28.70  ? 129 ARG C O   1 
ATOM   11902 C  CB  . ARG E 2 183 ? 112.522 132.441 101.575 1.00 21.51  ? 129 ARG C CB  1 
ATOM   11903 C  CG  . ARG E 2 183 ? 112.167 132.151 103.025 1.00 19.91  ? 129 ARG C CG  1 
ATOM   11904 C  CD  . ARG E 2 183 ? 111.095 131.098 103.158 1.00 20.19  ? 129 ARG C CD  1 
ATOM   11905 N  NE  . ARG E 2 183 ? 111.629 129.743 103.142 1.00 25.42  ? 129 ARG C NE  1 
ATOM   11906 C  CZ  . ARG E 2 183 ? 111.859 129.015 104.225 1.00 22.21  ? 129 ARG C CZ  1 
ATOM   11907 N  NH1 . ARG E 2 183 ? 111.593 129.474 105.434 1.00 21.85  ? 129 ARG C NH1 1 
ATOM   11908 N  NH2 . ARG E 2 183 ? 112.376 127.799 104.092 1.00 19.42  ? 129 ARG C NH2 1 
ATOM   11909 N  N   . ILE E 2 184 ? 114.590 134.864 103.008 1.00 21.23  ? 130 ILE C N   1 
ATOM   11910 C  CA  . ILE E 2 184 ? 115.872 135.261 103.577 1.00 21.35  ? 130 ILE C CA  1 
ATOM   11911 C  C   . ILE E 2 184 ? 115.815 135.151 105.090 1.00 23.58  ? 130 ILE C C   1 
ATOM   11912 O  O   . ILE E 2 184 ? 114.840 135.582 105.710 1.00 29.81  ? 130 ILE C O   1 
ATOM   11913 C  CB  . ILE E 2 184 ? 116.252 136.696 103.169 1.00 19.13  ? 130 ILE C CB  1 
ATOM   11914 C  CG1 . ILE E 2 184 ? 116.316 136.821 101.653 1.00 19.16  ? 130 ILE C CG1 1 
ATOM   11915 C  CG2 . ILE E 2 184 ? 117.571 137.094 103.779 1.00 22.35  ? 130 ILE C CG2 1 
ATOM   11916 C  CD1 . ILE E 2 184 ? 116.406 138.227 101.174 1.00 19.43  ? 130 ILE C CD1 1 
ATOM   11917 N  N   . THR E 2 185 ? 116.852 134.571 105.681 1.00 21.37  ? 131 THR C N   1 
ATOM   11918 C  CA  . THR E 2 185 ? 117.116 134.683 107.109 1.00 24.47  ? 131 THR C CA  1 
ATOM   11919 C  C   . THR E 2 185 ? 118.331 135.575 107.288 1.00 26.29  ? 131 THR C C   1 
ATOM   11920 O  O   . THR E 2 185 ? 119.390 135.302 106.720 1.00 29.51  ? 131 THR C O   1 
ATOM   11921 C  CB  . THR E 2 185 ? 117.365 133.324 107.754 1.00 28.39  ? 131 THR C CB  1 
ATOM   11922 O  OG1 . THR E 2 185 ? 116.164 132.552 107.728 1.00 36.75  ? 131 THR C OG1 1 
ATOM   11923 C  CG2 . THR E 2 185 ? 117.799 133.508 109.185 1.00 24.40  ? 131 THR C CG2 1 
ATOM   11924 N  N   . THR E 2 186 ? 118.176 136.637 108.064 1.00 29.13  ? 132 THR C N   1 
ATOM   11925 C  CA  . THR E 2 186 ? 119.226 137.623 108.253 1.00 29.91  ? 132 THR C CA  1 
ATOM   11926 C  C   . THR E 2 186 ? 119.395 137.924 109.731 1.00 27.86  ? 132 THR C C   1 
ATOM   11927 O  O   . THR E 2 186 ? 118.416 138.060 110.461 1.00 32.40  ? 132 THR C O   1 
ATOM   11928 C  CB  . THR E 2 186 ? 118.912 138.918 107.479 1.00 37.92  ? 132 THR C CB  1 
ATOM   11929 O  OG1 . THR E 2 186 ? 119.803 139.963 107.882 1.00 37.18  ? 132 THR C OG1 1 
ATOM   11930 C  CG2 . THR E 2 186 ? 117.489 139.354 107.717 1.00 34.94  ? 132 THR C CG2 1 
ATOM   11931 N  N   . THR E 2 187 ? 120.643 138.010 110.169 1.00 27.32  ? 133 THR C N   1 
ATOM   11932 C  CA  . THR E 2 187 ? 120.983 138.534 111.483 1.00 26.86  ? 133 THR C CA  1 
ATOM   11933 C  C   . THR E 2 187 ? 121.386 139.987 111.303 1.00 29.90  ? 133 THR C C   1 
ATOM   11934 O  O   . THR E 2 187 ? 122.290 140.284 110.522 1.00 38.39  ? 133 THR C O   1 
ATOM   11935 C  CB  . THR E 2 187 ? 122.115 137.740 112.125 1.00 26.79  ? 133 THR C CB  1 
ATOM   11936 O  OG1 . THR E 2 187 ? 121.640 136.444 112.495 1.00 32.52  ? 133 THR C OG1 1 
ATOM   11937 C  CG2 . THR E 2 187 ? 122.623 138.450 113.350 1.00 28.39  ? 133 THR C CG2 1 
ATOM   11938 N  N   . ALA E 2 188 ? 120.700 140.885 111.993 1.00 28.38  ? 134 ALA C N   1 
ATOM   11939 C  CA  . ALA E 2 188 ? 120.886 142.314 111.823 1.00 27.84  ? 134 ALA C CA  1 
ATOM   11940 C  C   . ALA E 2 188 ? 121.289 142.940 113.146 1.00 31.09  ? 134 ALA C C   1 
ATOM   11941 O  O   . ALA E 2 188 ? 120.802 142.539 114.205 1.00 35.72  ? 134 ALA C O   1 
ATOM   11942 C  CB  . ALA E 2 188 ? 119.616 142.971 111.303 1.00 29.10  ? 134 ALA C CB  1 
ATOM   11943 N  N   . ALA E 2 189 ? 122.172 143.929 113.076 1.00 27.93  ? 135 ALA C N   1 
ATOM   11944 C  CA  . ALA E 2 189 ? 122.649 144.591 114.279 1.00 29.44  ? 135 ALA C CA  1 
ATOM   11945 C  C   . ALA E 2 189 ? 121.578 145.499 114.867 1.00 36.46  ? 135 ALA C C   1 
ATOM   11946 O  O   . ALA E 2 189 ? 120.833 146.161 114.143 1.00 39.93  ? 135 ALA C O   1 
ATOM   11947 C  CB  . ALA E 2 189 ? 123.903 145.400 113.975 1.00 26.36  ? 135 ALA C CB  1 
ATOM   11948 N  N   . CYS E 2 190 ? 121.516 145.535 116.196 1.00 36.93  ? 136 CYS C N   1 
ATOM   11949 C  CA  . CYS E 2 190 ? 120.609 146.436 116.904 1.00 41.02  ? 136 CYS C CA  1 
ATOM   11950 C  C   . CYS E 2 190 ? 121.304 146.861 118.194 1.00 45.17  ? 136 CYS C C   1 
ATOM   11951 O  O   . CYS E 2 190 ? 121.242 146.141 119.192 1.00 51.22  ? 136 CYS C O   1 
ATOM   11952 C  CB  . CYS E 2 190 ? 119.269 145.770 117.190 1.00 40.29  ? 136 CYS C CB  1 
ATOM   11953 S  SG  . CYS E 2 190 ? 118.082 146.860 118.011 1.00 64.72  ? 136 CYS C SG  1 
ATOM   11954 N  N   . MET E 2 191 ? 121.961 148.018 118.168 1.00 41.22  ? 137 MET C N   1 
ATOM   11955 C  CA  . MET E 2 191 ? 122.562 148.552 119.381 1.00 44.63  ? 137 MET C CA  1 
ATOM   11956 C  C   . MET E 2 191 ? 121.473 148.925 120.377 1.00 47.15  ? 137 MET C C   1 
ATOM   11957 O  O   . MET E 2 191 ? 120.456 149.517 120.013 1.00 55.23  ? 137 MET C O   1 
ATOM   11958 C  CB  . MET E 2 191 ? 123.424 149.769 119.061 1.00 48.31  ? 137 MET C CB  1 
ATOM   11959 C  CG  . MET E 2 191 ? 124.356 149.571 117.883 1.00 63.40  ? 137 MET C CG  1 
ATOM   11960 S  SD  . MET E 2 191 ? 125.512 148.208 118.094 1.00 91.37  ? 137 MET C SD  1 
ATOM   11961 C  CE  . MET E 2 191 ? 126.463 148.790 119.494 1.00 59.68  ? 137 MET C CE  1 
ATOM   11962 N  N   . MET E 2 192 ? 121.690 148.586 121.642 1.00 45.47  ? 138 MET C N   1 
ATOM   11963 C  CA  . MET E 2 192 ? 120.656 148.695 122.658 1.00 46.82  ? 138 MET C CA  1 
ATOM   11964 C  C   . MET E 2 192 ? 121.093 149.609 123.793 1.00 50.50  ? 138 MET C C   1 
ATOM   11965 O  O   . MET E 2 192 ? 122.279 149.721 124.107 1.00 54.94  ? 138 MET C O   1 
ATOM   11966 C  CB  . MET E 2 192 ? 120.294 147.320 123.210 1.00 43.64  ? 138 MET C CB  1 
ATOM   11967 C  CG  . MET E 2 192 ? 119.872 146.350 122.142 1.00 49.23  ? 138 MET C CG  1 
ATOM   11968 S  SD  . MET E 2 192 ? 119.089 144.865 122.770 1.00 59.03  ? 138 MET C SD  1 
ATOM   11969 C  CE  . MET E 2 192 ? 119.045 143.889 121.276 1.00 45.47  ? 138 MET C CE  1 
ATOM   11970 N  N   . ASP E 2 193 ? 120.112 150.273 124.395 1.00 47.16  ? 139 ASP C N   1 
ATOM   11971 C  CA  . ASP E 2 193 ? 120.316 151.167 125.527 1.00 48.42  ? 139 ASP C CA  1 
ATOM   11972 C  C   . ASP E 2 193 ? 119.785 150.466 126.769 1.00 50.99  ? 139 ASP C C   1 
ATOM   11973 O  O   . ASP E 2 193 ? 118.569 150.332 126.940 1.00 53.04  ? 139 ASP C O   1 
ATOM   11974 C  CB  . ASP E 2 193 ? 119.606 152.498 125.298 1.00 60.55  ? 139 ASP C CB  1 
ATOM   11975 C  CG  . ASP E 2 193 ? 119.958 153.536 126.339 1.00 66.88  ? 139 ASP C CG  1 
ATOM   11976 O  OD1 . ASP E 2 193 ? 121.045 153.435 126.937 1.00 68.28  ? 139 ASP C OD1 1 
ATOM   11977 O  OD2 . ASP E 2 193 ? 119.143 154.455 126.556 1.00 67.66  ? 139 ASP C OD2 1 
ATOM   11978 N  N   . LEU E 2 194 ? 120.690 150.030 127.638 1.00 45.27  ? 140 LEU C N   1 
ATOM   11979 C  CA  . LEU E 2 194 ? 120.329 149.213 128.785 1.00 42.15  ? 140 LEU C CA  1 
ATOM   11980 C  C   . LEU E 2 194 ? 120.320 149.986 130.093 1.00 47.22  ? 140 LEU C C   1 
ATOM   11981 O  O   . LEU E 2 194 ? 120.289 149.369 131.159 1.00 52.77  ? 140 LEU C O   1 
ATOM   11982 C  CB  . LEU E 2 194 ? 121.279 148.026 128.898 1.00 36.74  ? 140 LEU C CB  1 
ATOM   11983 C  CG  . LEU E 2 194 ? 121.294 147.074 127.709 1.00 34.23  ? 140 LEU C CG  1 
ATOM   11984 C  CD1 . LEU E 2 194 ? 122.390 146.066 127.882 1.00 37.67  ? 140 LEU C CD1 1 
ATOM   11985 C  CD2 . LEU E 2 194 ? 119.964 146.382 127.574 1.00 38.70  ? 140 LEU C CD2 1 
ATOM   11986 N  N   . ARG E 2 195 ? 120.348 151.317 130.043 1.00 48.46  ? 141 ARG C N   1 
ATOM   11987 C  CA  . ARG E 2 195 ? 120.370 152.099 131.271 1.00 47.36  ? 141 ARG C CA  1 
ATOM   11988 C  C   . ARG E 2 195 ? 119.105 151.925 132.092 1.00 48.11  ? 141 ARG C C   1 
ATOM   11989 O  O   . ARG E 2 195 ? 119.127 152.175 133.299 1.00 54.69  ? 141 ARG C O   1 
ATOM   11990 C  CB  . ARG E 2 195 ? 120.571 153.575 130.949 1.00 49.38  ? 141 ARG C CB  1 
ATOM   11991 C  CG  . ARG E 2 195 ? 121.926 153.894 130.382 1.00 58.11  ? 141 ARG C CG  1 
ATOM   11992 C  CD  . ARG E 2 195 ? 122.015 155.343 129.964 1.00 67.04  ? 141 ARG C CD  1 
ATOM   11993 N  NE  . ARG E 2 195 ? 123.375 155.692 129.578 1.00 88.95  ? 141 ARG C NE  1 
ATOM   11994 C  CZ  . ARG E 2 195 ? 123.888 155.482 128.374 1.00 94.33  ? 141 ARG C CZ  1 
ATOM   11995 N  NH1 . ARG E 2 195 ? 123.166 154.956 127.399 1.00 88.49  ? 141 ARG C NH1 1 
ATOM   11996 N  NH2 . ARG E 2 195 ? 125.157 155.806 128.145 1.00 93.65  ? 141 ARG C NH2 1 
ATOM   11997 N  N   . ARG E 2 196 ? 118.008 151.504 131.474 1.00 40.83  ? 142 ARG C N   1 
ATOM   11998 C  CA  . ARG E 2 196 ? 116.739 151.356 132.168 1.00 40.33  ? 142 ARG C CA  1 
ATOM   11999 C  C   . ARG E 2 196 ? 116.339 149.895 132.322 1.00 46.46  ? 142 ARG C C   1 
ATOM   12000 O  O   . ARG E 2 196 ? 115.154 149.582 132.432 1.00 52.34  ? 142 ARG C O   1 
ATOM   12001 C  CB  . ARG E 2 196 ? 115.646 152.139 131.450 1.00 41.45  ? 142 ARG C CB  1 
ATOM   12002 C  CG  . ARG E 2 196 ? 115.406 153.503 132.044 1.00 41.23  ? 142 ARG C CG  1 
ATOM   12003 C  CD  . ARG E 2 196 ? 114.378 154.275 131.258 1.00 45.30  ? 142 ARG C CD  1 
ATOM   12004 N  NE  . ARG E 2 196 ? 113.765 155.313 132.072 1.00 58.81  ? 142 ARG C NE  1 
ATOM   12005 C  CZ  . ARG E 2 196 ? 112.622 155.167 132.726 1.00 66.25  ? 142 ARG C CZ  1 
ATOM   12006 N  NH1 . ARG E 2 196 ? 111.924 154.046 132.657 1.00 60.29  ? 142 ARG C NH1 1 
ATOM   12007 N  NH2 . ARG E 2 196 ? 112.169 156.172 133.468 1.00 72.60  ? 142 ARG C NH2 1 
ATOM   12008 N  N   . TYR E 2 197 ? 117.313 148.999 132.340 1.00 46.03  ? 143 TYR C N   1 
ATOM   12009 C  CA  . TYR E 2 197 ? 117.013 147.598 132.566 1.00 43.99  ? 143 TYR C CA  1 
ATOM   12010 C  C   . TYR E 2 197 ? 116.393 147.428 133.950 1.00 52.17  ? 143 TYR C C   1 
ATOM   12011 O  O   . TYR E 2 197 ? 116.859 148.041 134.916 1.00 55.95  ? 143 TYR C O   1 
ATOM   12012 C  CB  . TYR E 2 197 ? 118.287 146.764 132.447 1.00 41.22  ? 143 TYR C CB  1 
ATOM   12013 C  CG  . TYR E 2 197 ? 118.074 145.276 132.497 1.00 42.96  ? 143 TYR C CG  1 
ATOM   12014 C  CD1 . TYR E 2 197 ? 117.993 144.606 133.706 1.00 45.40  ? 143 TYR C CD1 1 
ATOM   12015 C  CD2 . TYR E 2 197 ? 117.973 144.537 131.337 1.00 45.29  ? 143 TYR C CD2 1 
ATOM   12016 C  CE1 . TYR E 2 197 ? 117.804 143.250 133.755 1.00 47.61  ? 143 TYR C CE1 1 
ATOM   12017 C  CE2 . TYR E 2 197 ? 117.790 143.178 131.377 1.00 49.93  ? 143 TYR C CE2 1 
ATOM   12018 C  CZ  . TYR E 2 197 ? 117.704 142.539 132.589 1.00 52.12  ? 143 TYR C CZ  1 
ATOM   12019 O  OH  . TYR E 2 197 ? 117.515 141.181 132.634 1.00 54.76  ? 143 TYR C OH  1 
ATOM   12020 N  N   . PRO E 2 198 ? 115.343 146.612 134.089 1.00 48.53  ? 144 PRO C N   1 
ATOM   12021 C  CA  . PRO E 2 198 ? 114.667 145.804 133.073 1.00 41.66  ? 144 PRO C CA  1 
ATOM   12022 C  C   . PRO E 2 198 ? 113.518 146.511 132.385 1.00 44.06  ? 144 PRO C C   1 
ATOM   12023 O  O   . PRO E 2 198 ? 112.825 145.908 131.583 1.00 49.39  ? 144 PRO C O   1 
ATOM   12024 C  CB  . PRO E 2 198 ? 114.154 144.627 133.891 1.00 45.10  ? 144 PRO C CB  1 
ATOM   12025 C  CG  . PRO E 2 198 ? 113.757 145.271 135.177 1.00 49.27  ? 144 PRO C CG  1 
ATOM   12026 C  CD  . PRO E 2 198 ? 114.782 146.351 135.423 1.00 46.14  ? 144 PRO C CD  1 
ATOM   12027 N  N   . LEU E 2 199 ? 113.275 147.787 132.676 1.00 46.38  ? 145 LEU C N   1 
ATOM   12028 C  CA  . LEU E 2 199 ? 112.175 148.523 132.069 1.00 45.93  ? 145 LEU C CA  1 
ATOM   12029 C  C   . LEU E 2 199 ? 112.591 149.243 130.797 1.00 45.63  ? 145 LEU C C   1 
ATOM   12030 O  O   . LEU E 2 199 ? 111.999 150.269 130.445 1.00 48.02  ? 145 LEU C O   1 
ATOM   12031 C  CB  . LEU E 2 199 ? 111.590 149.504 133.081 1.00 47.47  ? 145 LEU C CB  1 
ATOM   12032 C  CG  . LEU E 2 199 ? 111.093 148.856 134.373 1.00 50.19  ? 145 LEU C CG  1 
ATOM   12033 C  CD1 . LEU E 2 199 ? 110.523 149.899 135.300 1.00 57.39  ? 145 LEU C CD1 1 
ATOM   12034 C  CD2 . LEU E 2 199 ? 110.057 147.796 134.075 1.00 52.75  ? 145 LEU C CD2 1 
ATOM   12035 N  N   . ASP E 2 200 ? 113.595 148.729 130.098 1.00 45.43  ? 146 ASP C N   1 
ATOM   12036 C  CA  . ASP E 2 200 ? 114.129 149.373 128.914 1.00 42.45  ? 146 ASP C CA  1 
ATOM   12037 C  C   . ASP E 2 200 ? 113.221 149.149 127.712 1.00 45.69  ? 146 ASP C C   1 
ATOM   12038 O  O   . ASP E 2 200 ? 112.406 148.227 127.677 1.00 52.14  ? 146 ASP C O   1 
ATOM   12039 C  CB  . ASP E 2 200 ? 115.530 148.851 128.613 1.00 43.20  ? 146 ASP C CB  1 
ATOM   12040 C  CG  . ASP E 2 200 ? 115.557 147.359 128.410 1.00 45.49  ? 146 ASP C CG  1 
ATOM   12041 O  OD1 . ASP E 2 200 ? 114.671 146.678 128.952 1.00 47.37  ? 146 ASP C OD1 1 
ATOM   12042 O  OD2 . ASP E 2 200 ? 116.462 146.862 127.710 1.00 49.17  ? 146 ASP C OD2 1 
ATOM   12043 N  N   . GLU E 2 201 ? 113.373 150.018 126.717 1.00 48.40  ? 147 GLU C N   1 
ATOM   12044 C  CA  . GLU E 2 201 ? 112.647 149.927 125.460 1.00 42.18  ? 147 GLU C CA  1 
ATOM   12045 C  C   . GLU E 2 201 ? 113.632 150.121 124.320 1.00 43.80  ? 147 GLU C C   1 
ATOM   12046 O  O   . GLU E 2 201 ? 114.402 151.085 124.325 1.00 47.42  ? 147 GLU C O   1 
ATOM   12047 C  CB  . GLU E 2 201 ? 111.535 150.972 125.401 1.00 40.93  ? 147 GLU C CB  1 
ATOM   12048 C  CG  . GLU E 2 201 ? 110.606 150.828 124.229 1.00 47.92  ? 147 GLU C CG  1 
ATOM   12049 C  CD  . GLU E 2 201 ? 109.205 151.270 124.563 1.00 64.05  ? 147 GLU C CD  1 
ATOM   12050 O  OE1 . GLU E 2 201 ? 108.927 151.485 125.760 1.00 67.46  ? 147 GLU C OE1 1 
ATOM   12051 O  OE2 . GLU E 2 201 ? 108.381 151.404 123.636 1.00 68.81  ? 147 GLU C OE2 1 
ATOM   12052 N  N   . GLN E 2 202 ? 113.611 149.216 123.349 1.00 42.85  ? 148 GLN C N   1 
ATOM   12053 C  CA  . GLN E 2 202 ? 114.585 149.227 122.269 1.00 38.94  ? 148 GLN C CA  1 
ATOM   12054 C  C   . GLN E 2 202 ? 113.919 149.556 120.942 1.00 37.62  ? 148 GLN C C   1 
ATOM   12055 O  O   . GLN E 2 202 ? 112.703 149.454 120.789 1.00 42.65  ? 148 GLN C O   1 
ATOM   12056 C  CB  . GLN E 2 202 ? 115.308 147.884 122.165 1.00 36.43  ? 148 GLN C CB  1 
ATOM   12057 C  CG  . GLN E 2 202 ? 115.775 147.333 123.492 1.00 40.17  ? 148 GLN C CG  1 
ATOM   12058 C  CD  . GLN E 2 202 ? 116.732 148.257 124.204 1.00 45.24  ? 148 GLN C CD  1 
ATOM   12059 O  OE1 . GLN E 2 202 ? 117.546 148.925 123.582 1.00 47.40  ? 148 GLN C OE1 1 
ATOM   12060 N  NE2 . GLN E 2 202 ? 116.639 148.296 125.521 1.00 44.84  ? 148 GLN C NE2 1 
ATOM   12061 N  N   . ASN E 2 203 ? 114.744 149.946 119.976 1.00 34.88  ? 149 ASN C N   1 
ATOM   12062 C  CA  . ASN E 2 203 ? 114.299 150.286 118.629 1.00 34.77  ? 149 ASN C CA  1 
ATOM   12063 C  C   . ASN E 2 203 ? 115.256 149.616 117.654 1.00 40.33  ? 149 ASN C C   1 
ATOM   12064 O  O   . ASN E 2 203 ? 116.410 150.032 117.533 1.00 43.81  ? 149 ASN C O   1 
ATOM   12065 C  CB  . ASN E 2 203 ? 114.263 151.803 118.445 1.00 35.22  ? 149 ASN C CB  1 
ATOM   12066 C  CG  . ASN E 2 203 ? 113.989 152.231 117.019 1.00 42.91  ? 149 ASN C CG  1 
ATOM   12067 O  OD1 . ASN E 2 203 ? 113.709 151.419 116.148 1.00 45.53  ? 149 ASN C OD1 1 
ATOM   12068 N  ND2 . ASN E 2 203 ? 114.061 153.531 116.784 1.00 48.80  ? 149 ASN C ND2 1 
ATOM   12069 N  N   . CYS E 2 204 ? 114.779 148.587 116.962 1.00 40.79  ? 150 CYS C N   1 
ATOM   12070 C  CA  . CYS E 2 204 ? 115.604 147.776 116.074 1.00 40.27  ? 150 CYS C CA  1 
ATOM   12071 C  C   . CYS E 2 204 ? 115.157 147.967 114.632 1.00 42.83  ? 150 CYS C C   1 
ATOM   12072 O  O   . CYS E 2 204 ? 113.965 147.875 114.336 1.00 46.05  ? 150 CYS C O   1 
ATOM   12073 C  CB  . CYS E 2 204 ? 115.529 146.297 116.452 1.00 39.66  ? 150 CYS C CB  1 
ATOM   12074 S  SG  . CYS E 2 204 ? 116.310 145.863 118.023 1.00 65.14  ? 150 CYS C SG  1 
ATOM   12075 N  N   . THR E 2 205 ? 116.107 148.210 113.737 1.00 42.60  ? 151 THR C N   1 
ATOM   12076 C  CA  . THR E 2 205 ? 115.794 148.554 112.359 1.00 41.78  ? 151 THR C CA  1 
ATOM   12077 C  C   . THR E 2 205 ? 116.395 147.549 111.389 1.00 40.52  ? 151 THR C C   1 
ATOM   12078 O  O   . THR E 2 205 ? 117.365 146.854 111.700 1.00 45.28  ? 151 THR C O   1 
ATOM   12079 C  CB  . THR E 2 205 ? 116.302 149.956 111.993 1.00 41.60  ? 151 THR C CB  1 
ATOM   12080 O  OG1 . THR E 2 205 ? 117.731 149.986 112.056 1.00 43.71  ? 151 THR C OG1 1 
ATOM   12081 C  CG2 . THR E 2 205 ? 115.745 150.994 112.940 1.00 45.63  ? 151 THR C CG2 1 
ATOM   12082 N  N   . LEU E 2 206 ? 115.777 147.464 110.216 1.00 35.26  ? 152 LEU C N   1 
ATOM   12083 C  CA  . LEU E 2 206 ? 116.355 146.835 109.037 1.00 32.78  ? 152 LEU C CA  1 
ATOM   12084 C  C   . LEU E 2 206 ? 116.461 147.906 107.964 1.00 35.34  ? 152 LEU C C   1 
ATOM   12085 O  O   . LEU E 2 206 ? 115.458 148.542 107.618 1.00 38.32  ? 152 LEU C O   1 
ATOM   12086 C  CB  . LEU E 2 206 ? 115.501 145.665 108.553 1.00 29.59  ? 152 LEU C CB  1 
ATOM   12087 C  CG  . LEU E 2 206 ? 116.081 144.842 107.403 1.00 29.42  ? 152 LEU C CG  1 
ATOM   12088 C  CD1 . LEU E 2 206 ? 117.243 143.991 107.873 1.00 33.88  ? 152 LEU C CD1 1 
ATOM   12089 C  CD2 . LEU E 2 206 ? 115.021 143.980 106.765 1.00 24.36  ? 152 LEU C CD2 1 
ATOM   12090 N  N   . GLU E 2 207 ? 117.672 148.114 107.458 1.00 29.97  ? 153 GLU C N   1 
ATOM   12091 C  CA  . GLU E 2 207 ? 117.961 149.141 106.469 1.00 30.32  ? 153 GLU C CA  1 
ATOM   12092 C  C   . GLU E 2 207 ? 118.198 148.483 105.121 1.00 32.11  ? 153 GLU C C   1 
ATOM   12093 O  O   . GLU E 2 207 ? 118.998 147.552 105.018 1.00 33.74  ? 153 GLU C O   1 
ATOM   12094 C  CB  . GLU E 2 207 ? 119.189 149.954 106.874 1.00 29.42  ? 153 GLU C CB  1 
ATOM   12095 C  CG  . GLU E 2 207 ? 119.182 150.416 108.311 1.00 33.97  ? 153 GLU C CG  1 
ATOM   12096 C  CD  . GLU E 2 207 ? 118.270 151.596 108.541 1.00 46.43  ? 153 GLU C CD  1 
ATOM   12097 O  OE1 . GLU E 2 207 ? 118.027 152.362 107.589 1.00 42.91  ? 153 GLU C OE1 1 
ATOM   12098 O  OE2 . GLU E 2 207 ? 117.793 151.763 109.679 1.00 54.81  ? 153 GLU C OE2 1 
ATOM   12099 N  N   . ILE E 2 208 ? 117.520 148.979 104.093 1.00 32.38  ? 154 ILE C N   1 
ATOM   12100 C  CA  . ILE E 2 208 ? 117.519 148.385 102.764 1.00 30.48  ? 154 ILE C CA  1 
ATOM   12101 C  C   . ILE E 2 208 ? 118.022 149.431 101.784 1.00 32.77  ? 154 ILE C C   1 
ATOM   12102 O  O   . ILE E 2 208 ? 117.490 150.544 101.740 1.00 38.15  ? 154 ILE C O   1 
ATOM   12103 C  CB  . ILE E 2 208 ? 116.109 147.907 102.380 1.00 24.93  ? 154 ILE C CB  1 
ATOM   12104 C  CG1 . ILE E 2 208 ? 115.644 146.807 103.327 1.00 22.58  ? 154 ILE C CG1 1 
ATOM   12105 C  CG2 . ILE E 2 208 ? 116.072 147.457 100.955 1.00 25.22  ? 154 ILE C CG2 1 
ATOM   12106 C  CD1 . ILE E 2 208 ? 114.178 146.516 103.244 1.00 22.20  ? 154 ILE C CD1 1 
ATOM   12107 N  N   . GLU E 2 209 ? 119.033 149.079 100.996 1.00 29.49  ? 155 GLU C N   1 
ATOM   12108 C  CA  . GLU E 2 209 ? 119.657 150.066 100.130 1.00 30.09  ? 155 GLU C CA  1 
ATOM   12109 C  C   . GLU E 2 209 ? 120.121 149.404 98.844  1.00 33.25  ? 155 GLU C C   1 
ATOM   12110 O  O   . GLU E 2 209 ? 120.285 148.188 98.771  1.00 37.27  ? 155 GLU C O   1 
ATOM   12111 C  CB  . GLU E 2 209 ? 120.827 150.756 100.837 1.00 33.55  ? 155 GLU C CB  1 
ATOM   12112 C  CG  . GLU E 2 209 ? 121.410 151.940 100.098 1.00 41.33  ? 155 GLU C CG  1 
ATOM   12113 C  CD  . GLU E 2 209 ? 122.271 152.817 100.973 1.00 51.10  ? 155 GLU C CD  1 
ATOM   12114 O  OE1 . GLU E 2 209 ? 121.995 152.902 102.184 1.00 53.57  ? 155 GLU C OE1 1 
ATOM   12115 O  OE2 . GLU E 2 209 ? 123.223 153.427 100.450 1.00 53.31  ? 155 GLU C OE2 1 
ATOM   12116 N  N   . SER E 2 210 ? 120.296 150.223 97.814  1.00 34.40  ? 156 SER C N   1 
ATOM   12117 C  CA  . SER E 2 210 ? 120.885 149.783 96.559  1.00 33.64  ? 156 SER C CA  1 
ATOM   12118 C  C   . SER E 2 210 ? 122.396 149.942 96.649  1.00 35.89  ? 156 SER C C   1 
ATOM   12119 O  O   . SER E 2 210 ? 122.889 151.034 96.940  1.00 43.33  ? 156 SER C O   1 
ATOM   12120 C  CB  . SER E 2 210 ? 120.324 150.592 95.395  1.00 33.69  ? 156 SER C CB  1 
ATOM   12121 O  OG  . SER E 2 210 ? 120.719 150.031 94.162  1.00 41.81  ? 156 SER C OG  1 
ATOM   12122 N  N   . TYR E 2 211 ? 123.131 148.858 96.402  1.00 30.87  ? 157 TYR C N   1 
ATOM   12123 C  CA  . TYR E 2 211 ? 124.572 148.907 96.623  1.00 31.38  ? 157 TYR C CA  1 
ATOM   12124 C  C   . TYR E 2 211 ? 125.289 149.722 95.553  1.00 35.19  ? 157 TYR C C   1 
ATOM   12125 O  O   . TYR E 2 211 ? 126.169 150.526 95.871  1.00 37.47  ? 157 TYR C O   1 
ATOM   12126 C  CB  . TYR E 2 211 ? 125.158 147.500 96.690  1.00 27.85  ? 157 TYR C CB  1 
ATOM   12127 C  CG  . TYR E 2 211 ? 126.590 147.505 97.150  1.00 29.33  ? 157 TYR C CG  1 
ATOM   12128 C  CD1 . TYR E 2 211 ? 126.900 147.510 98.496  1.00 33.68  ? 157 TYR C CD1 1 
ATOM   12129 C  CD2 . TYR E 2 211 ? 127.630 147.530 96.243  1.00 31.92  ? 157 TYR C CD2 1 
ATOM   12130 C  CE1 . TYR E 2 211 ? 128.201 147.531 98.923  1.00 34.20  ? 157 TYR C CE1 1 
ATOM   12131 C  CE2 . TYR E 2 211 ? 128.932 147.550 96.662  1.00 35.77  ? 157 TYR C CE2 1 
ATOM   12132 C  CZ  . TYR E 2 211 ? 129.211 147.550 98.002  1.00 37.70  ? 157 TYR C CZ  1 
ATOM   12133 O  OH  . TYR E 2 211 ? 130.513 147.568 98.425  1.00 52.26  ? 157 TYR C OH  1 
ATOM   12134 N  N   . GLY E 2 212 ? 124.943 149.526 94.287  1.00 34.91  ? 158 GLY C N   1 
ATOM   12135 C  CA  . GLY E 2 212 ? 125.752 150.084 93.223  1.00 31.25  ? 158 GLY C CA  1 
ATOM   12136 C  C   . GLY E 2 212 ? 125.139 151.230 92.452  1.00 36.26  ? 158 GLY C C   1 
ATOM   12137 O  O   . GLY E 2 212 ? 125.863 152.019 91.842  1.00 44.21  ? 158 GLY C O   1 
ATOM   12138 N  N   . TYR E 2 213 ? 123.816 151.333 92.460  1.00 34.46  ? 159 TYR C N   1 
ATOM   12139 C  CA  . TYR E 2 213 ? 123.102 152.338 91.686  1.00 34.91  ? 159 TYR C CA  1 
ATOM   12140 C  C   . TYR E 2 213 ? 122.669 153.490 92.577  1.00 37.33  ? 159 TYR C C   1 
ATOM   12141 O  O   . TYR E 2 213 ? 122.175 153.277 93.684  1.00 40.75  ? 159 TYR C O   1 
ATOM   12142 C  CB  . TYR E 2 213 ? 121.878 151.731 91.006  1.00 37.48  ? 159 TYR C CB  1 
ATOM   12143 C  CG  . TYR E 2 213 ? 122.193 150.678 89.974  1.00 41.69  ? 159 TYR C CG  1 
ATOM   12144 C  CD1 . TYR E 2 213 ? 122.473 151.028 88.666  1.00 44.34  ? 159 TYR C CD1 1 
ATOM   12145 C  CD2 . TYR E 2 213 ? 122.193 149.334 90.305  1.00 38.12  ? 159 TYR C CD2 1 
ATOM   12146 C  CE1 . TYR E 2 213 ? 122.752 150.074 87.721  1.00 44.43  ? 159 TYR C CE1 1 
ATOM   12147 C  CE2 . TYR E 2 213 ? 122.472 148.375 89.367  1.00 36.92  ? 159 TYR C CE2 1 
ATOM   12148 C  CZ  . TYR E 2 213 ? 122.752 148.750 88.077  1.00 45.01  ? 159 TYR C CZ  1 
ATOM   12149 O  OH  . TYR E 2 213 ? 123.025 147.793 87.135  1.00 54.22  ? 159 TYR C OH  1 
ATOM   12150 N  N   . THR E 2 214 ? 122.852 154.710 92.086  1.00 37.82  ? 160 THR C N   1 
ATOM   12151 C  CA  . THR E 2 214 ? 122.456 155.901 92.816  1.00 35.96  ? 160 THR C CA  1 
ATOM   12152 C  C   . THR E 2 214 ? 121.013 156.272 92.481  1.00 39.18  ? 160 THR C C   1 
ATOM   12153 O  O   . THR E 2 214 ? 120.316 155.564 91.754  1.00 43.76  ? 160 THR C O   1 
ATOM   12154 C  CB  . THR E 2 214 ? 123.403 157.056 92.503  1.00 41.23  ? 160 THR C CB  1 
ATOM   12155 O  OG1 . THR E 2 214 ? 123.431 157.282 91.092  1.00 47.03  ? 160 THR C OG1 1 
ATOM   12156 C  CG2 . THR E 2 214 ? 124.798 156.732 92.978  1.00 41.08  ? 160 THR C CG2 1 
ATOM   12157 N  N   . THR E 2 215 ? 120.560 157.409 93.010  1.00 40.14  ? 161 THR C N   1 
ATOM   12158 C  CA  . THR E 2 215 ? 119.196 157.865 92.771  1.00 41.53  ? 161 THR C CA  1 
ATOM   12159 C  C   . THR E 2 215 ? 118.976 158.356 91.348  1.00 48.28  ? 161 THR C C   1 
ATOM   12160 O  O   . THR E 2 215 ? 117.833 158.642 90.982  1.00 50.08  ? 161 THR C O   1 
ATOM   12161 C  CB  . THR E 2 215 ? 118.823 158.972 93.753  1.00 44.00  ? 161 THR C CB  1 
ATOM   12162 O  OG1 . THR E 2 215 ? 119.703 160.086 93.581  1.00 54.53  ? 161 THR C OG1 1 
ATOM   12163 C  CG2 . THR E 2 215 ? 118.929 158.466 95.169  1.00 39.31  ? 161 THR C CG2 1 
ATOM   12164 N  N   . ASP E 2 216 ? 120.033 158.489 90.551  1.00 47.76  ? 162 ASP C N   1 
ATOM   12165 C  CA  . ASP E 2 216 ? 119.857 158.779 89.137  1.00 52.09  ? 162 ASP C CA  1 
ATOM   12166 C  C   . ASP E 2 216 ? 119.489 157.545 88.329  1.00 52.61  ? 162 ASP C C   1 
ATOM   12167 O  O   . ASP E 2 216 ? 119.034 157.683 87.190  1.00 59.31  ? 162 ASP C O   1 
ATOM   12168 C  CB  . ASP E 2 216 ? 121.130 159.395 88.562  1.00 62.78  ? 162 ASP C CB  1 
ATOM   12169 C  CG  . ASP E 2 216 ? 121.402 160.777 89.107  1.00 76.50  ? 162 ASP C CG  1 
ATOM   12170 O  OD1 . ASP E 2 216 ? 120.429 161.515 89.369  1.00 72.70  ? 162 ASP C OD1 1 
ATOM   12171 O  OD2 . ASP E 2 216 ? 122.589 161.129 89.270  1.00 86.43  ? 162 ASP C OD2 1 
ATOM   12172 N  N   . ASP E 2 217 ? 119.663 156.354 88.888  1.00 46.93  ? 163 ASP C N   1 
ATOM   12173 C  CA  . ASP E 2 217 ? 119.419 155.117 88.164  1.00 44.98  ? 163 ASP C CA  1 
ATOM   12174 C  C   . ASP E 2 217 ? 118.326 154.250 88.764  1.00 45.50  ? 163 ASP C C   1 
ATOM   12175 O  O   . ASP E 2 217 ? 117.625 153.575 88.014  1.00 52.17  ? 163 ASP C O   1 
ATOM   12176 C  CB  . ASP E 2 217 ? 120.708 154.288 88.074  1.00 46.57  ? 163 ASP C CB  1 
ATOM   12177 C  CG  . ASP E 2 217 ? 121.802 154.993 87.298  1.00 63.93  ? 163 ASP C CG  1 
ATOM   12178 O  OD1 . ASP E 2 217 ? 121.476 155.762 86.372  1.00 70.88  ? 163 ASP C OD1 1 
ATOM   12179 O  OD2 . ASP E 2 217 ? 122.991 154.781 87.609  1.00 64.77  ? 163 ASP C OD2 1 
ATOM   12180 N  N   . ILE E 2 218 ? 118.152 154.249 90.084  1.00 43.88  ? 164 ILE C N   1 
ATOM   12181 C  CA  . ILE E 2 218 ? 117.170 153.394 90.732  1.00 39.80  ? 164 ILE C CA  1 
ATOM   12182 C  C   . ILE E 2 218 ? 116.394 154.212 91.754  1.00 41.09  ? 164 ILE C C   1 
ATOM   12183 O  O   . ILE E 2 218 ? 116.851 155.251 92.230  1.00 42.02  ? 164 ILE C O   1 
ATOM   12184 C  CB  . ILE E 2 218 ? 117.830 152.173 91.398  1.00 33.28  ? 164 ILE C CB  1 
ATOM   12185 C  CG1 . ILE E 2 218 ? 116.871 150.993 91.455  1.00 36.79  ? 164 ILE C CG1 1 
ATOM   12186 C  CG2 . ILE E 2 218 ? 118.282 152.512 92.784  1.00 34.99  ? 164 ILE C CG2 1 
ATOM   12187 C  CD1 . ILE E 2 218 ? 117.549 149.702 91.800  1.00 39.68  ? 164 ILE C CD1 1 
ATOM   12188 N  N   . GLU E 2 219 ? 115.192 153.739 92.071  1.00 44.01  ? 165 GLU C N   1 
ATOM   12189 C  CA  . GLU E 2 219 ? 114.345 154.359 93.079  1.00 41.90  ? 165 GLU C CA  1 
ATOM   12190 C  C   . GLU E 2 219 ? 113.601 153.277 93.841  1.00 37.47  ? 165 GLU C C   1 
ATOM   12191 O  O   . GLU E 2 219 ? 113.192 152.274 93.258  1.00 40.12  ? 165 GLU C O   1 
ATOM   12192 C  CB  . GLU E 2 219 ? 113.342 155.333 92.457  1.00 42.60  ? 165 GLU C CB  1 
ATOM   12193 C  CG  . GLU E 2 219 ? 113.967 156.614 91.960  1.00 52.51  ? 165 GLU C CG  1 
ATOM   12194 C  CD  . GLU E 2 219 ? 112.943 157.675 91.657  1.00 71.50  ? 165 GLU C CD  1 
ATOM   12195 O  OE1 . GLU E 2 219 ? 111.797 157.315 91.321  1.00 75.61  ? 165 GLU C OE1 1 
ATOM   12196 O  OE2 . GLU E 2 219 ? 113.284 158.871 91.759  1.00 80.68  ? 165 GLU C OE2 1 
ATOM   12197 N  N   . PHE E 2 220 ? 113.417 153.492 95.138  1.00 31.12  ? 166 PHE C N   1 
ATOM   12198 C  CA  . PHE E 2 220 ? 112.725 152.551 96.006  1.00 30.12  ? 166 PHE C CA  1 
ATOM   12199 C  C   . PHE E 2 220 ? 111.430 153.163 96.516  1.00 33.16  ? 166 PHE C C   1 
ATOM   12200 O  O   . PHE E 2 220 ? 111.338 154.374 96.717  1.00 41.82  ? 166 PHE C O   1 
ATOM   12201 C  CB  . PHE E 2 220 ? 113.578 152.162 97.211  1.00 29.98  ? 166 PHE C CB  1 
ATOM   12202 C  CG  . PHE E 2 220 ? 114.733 151.271 96.891  1.00 27.73  ? 166 PHE C CG  1 
ATOM   12203 C  CD1 . PHE E 2 220 ? 114.954 150.824 95.609  1.00 29.41  ? 166 PHE C CD1 1 
ATOM   12204 C  CD2 . PHE E 2 220 ? 115.592 150.869 97.890  1.00 26.63  ? 166 PHE C CD2 1 
ATOM   12205 C  CE1 . PHE E 2 220 ? 116.016 150.009 95.329  1.00 29.22  ? 166 PHE C CE1 1 
ATOM   12206 C  CE2 . PHE E 2 220 ? 116.650 150.053 97.614  1.00 26.54  ? 166 PHE C CE2 1 
ATOM   12207 C  CZ  . PHE E 2 220 ? 116.863 149.622 96.332  1.00 29.66  ? 166 PHE C CZ  1 
ATOM   12208 N  N   . TYR E 2 221 ? 110.429 152.315 96.726  1.00 30.17  ? 167 TYR C N   1 
ATOM   12209 C  CA  . TYR E 2 221 ? 109.223 152.727 97.426  1.00 31.91  ? 167 TYR C CA  1 
ATOM   12210 C  C   . TYR E 2 221 ? 108.608 151.512 98.098  1.00 34.27  ? 167 TYR C C   1 
ATOM   12211 O  O   . TYR E 2 221 ? 108.769 150.383 97.634  1.00 36.56  ? 167 TYR C O   1 
ATOM   12212 C  CB  . TYR E 2 221 ? 108.210 153.403 96.492  1.00 31.12  ? 167 TYR C CB  1 
ATOM   12213 C  CG  . TYR E 2 221 ? 107.665 152.521 95.399  1.00 31.94  ? 167 TYR C CG  1 
ATOM   12214 C  CD1 . TYR E 2 221 ? 108.361 152.342 94.221  1.00 34.18  ? 167 TYR C CD1 1 
ATOM   12215 C  CD2 . TYR E 2 221 ? 106.441 151.890 95.536  1.00 31.66  ? 167 TYR C CD2 1 
ATOM   12216 C  CE1 . TYR E 2 221 ? 107.868 151.541 93.220  1.00 37.53  ? 167 TYR C CE1 1 
ATOM   12217 C  CE2 . TYR E 2 221 ? 105.941 151.089 94.543  1.00 34.28  ? 167 TYR C CE2 1 
ATOM   12218 C  CZ  . TYR E 2 221 ? 106.658 150.918 93.386  1.00 38.18  ? 167 TYR C CZ  1 
ATOM   12219 O  OH  . TYR E 2 221 ? 106.166 150.118 92.387  1.00 44.07  ? 167 TYR C OH  1 
ATOM   12220 N  N   . TRP E 2 222 ? 107.922 151.753 99.211  1.00 33.82  ? 168 TRP C N   1 
ATOM   12221 C  CA  . TRP E 2 222 ? 107.205 150.698 99.916  1.00 28.22  ? 168 TRP C CA  1 
ATOM   12222 C  C   . TRP E 2 222 ? 105.930 150.403 99.146  1.00 33.34  ? 168 TRP C C   1 
ATOM   12223 O  O   . TRP E 2 222 ? 104.998 151.210 99.145  1.00 40.89  ? 168 TRP C O   1 
ATOM   12224 C  CB  . TRP E 2 222 ? 106.893 151.116 101.348 1.00 27.85  ? 168 TRP C CB  1 
ATOM   12225 C  CG  . TRP E 2 222 ? 108.045 151.017 102.284 1.00 24.69  ? 168 TRP C CG  1 
ATOM   12226 C  CD1 . TRP E 2 222 ? 108.681 152.041 102.907 1.00 23.30  ? 168 TRP C CD1 1 
ATOM   12227 C  CD2 . TRP E 2 222 ? 108.698 149.821 102.713 1.00 24.73  ? 168 TRP C CD2 1 
ATOM   12228 N  NE1 . TRP E 2 222 ? 109.690 151.561 103.695 1.00 23.24  ? 168 TRP C NE1 1 
ATOM   12229 C  CE2 . TRP E 2 222 ? 109.720 150.198 103.593 1.00 22.50  ? 168 TRP C CE2 1 
ATOM   12230 C  CE3 . TRP E 2 222 ? 108.517 148.467 102.435 1.00 24.76  ? 168 TRP C CE3 1 
ATOM   12231 C  CZ2 . TRP E 2 222 ? 110.557 149.275 104.197 1.00 21.19  ? 168 TRP C CZ2 1 
ATOM   12232 C  CZ3 . TRP E 2 222 ? 109.345 147.556 103.033 1.00 24.37  ? 168 TRP C CZ3 1 
ATOM   12233 C  CH2 . TRP E 2 222 ? 110.353 147.961 103.908 1.00 21.31  ? 168 TRP C CH2 1 
ATOM   12234 N  N   . ARG E 2 223 ? 105.891 149.257 98.479  1.00 34.45  ? 169 ARG C N   1 
ATOM   12235 C  CA  . ARG E 2 223 ? 104.765 148.920 97.620  1.00 35.08  ? 169 ARG C CA  1 
ATOM   12236 C  C   . ARG E 2 223 ? 103.555 148.583 98.476  1.00 39.71  ? 169 ARG C C   1 
ATOM   12237 O  O   . ARG E 2 223 ? 103.533 147.555 99.158  1.00 40.33  ? 169 ARG C O   1 
ATOM   12238 C  CB  . ARG E 2 223 ? 105.131 147.756 96.711  1.00 32.77  ? 169 ARG C CB  1 
ATOM   12239 C  CG  . ARG E 2 223 ? 104.000 147.313 95.825  1.00 34.59  ? 169 ARG C CG  1 
ATOM   12240 C  CD  . ARG E 2 223 ? 104.439 146.184 94.943  1.00 41.03  ? 169 ARG C CD  1 
ATOM   12241 N  NE  . ARG E 2 223 ? 103.343 145.293 94.592  1.00 46.23  ? 169 ARG C NE  1 
ATOM   12242 C  CZ  . ARG E 2 223 ? 102.640 145.385 93.473  1.00 49.70  ? 169 ARG C CZ  1 
ATOM   12243 N  NH1 . ARG E 2 223 ? 102.887 146.328 92.581  1.00 45.71  ? 169 ARG C NH1 1 
ATOM   12244 N  NH2 . ARG E 2 223 ? 101.671 144.505 93.243  1.00 50.03  ? 169 ARG C NH2 1 
ATOM   12245 N  N   . GLY E 2 224 ? 102.540 149.437 98.431  1.00 41.62  ? 170 GLY C N   1 
ATOM   12246 C  CA  . GLY E 2 224 ? 101.358 149.262 99.240  1.00 40.97  ? 170 GLY C CA  1 
ATOM   12247 C  C   . GLY E 2 224 ? 101.241 150.177 100.436 1.00 42.60  ? 170 GLY C C   1 
ATOM   12248 O  O   . GLY E 2 224 ? 100.323 149.992 101.239 1.00 48.63  ? 170 GLY C O   1 
ATOM   12249 N  N   . GLY E 2 225 ? 102.126 151.158 100.579 1.00 41.96  ? 171 GLY C N   1 
ATOM   12250 C  CA  . GLY E 2 225 ? 102.025 152.068 101.707 1.00 43.69  ? 171 GLY C CA  1 
ATOM   12251 C  C   . GLY E 2 225 ? 102.430 151.397 103.004 1.00 45.06  ? 171 GLY C C   1 
ATOM   12252 O  O   . GLY E 2 225 ? 103.402 150.638 103.063 1.00 47.49  ? 171 GLY C O   1 
ATOM   12253 N  N   . ASP E 2 226 ? 101.684 151.690 104.069 1.00 49.10  ? 172 ASP C N   1 
ATOM   12254 C  CA  . ASP E 2 226 ? 101.954 151.065 105.356 1.00 52.93  ? 172 ASP C CA  1 
ATOM   12255 C  C   . ASP E 2 226 ? 101.551 149.602 105.391 1.00 54.18  ? 172 ASP C C   1 
ATOM   12256 O  O   . ASP E 2 226 ? 101.933 148.894 106.326 1.00 55.73  ? 172 ASP C O   1 
ATOM   12257 C  CB  . ASP E 2 226 ? 101.237 151.815 106.474 1.00 57.56  ? 172 ASP C CB  1 
ATOM   12258 C  CG  . ASP E 2 226 ? 101.720 153.236 106.620 1.00 68.77  ? 172 ASP C CG  1 
ATOM   12259 O  OD1 . ASP E 2 226 ? 102.914 153.489 106.358 1.00 66.26  ? 172 ASP C OD1 1 
ATOM   12260 O  OD2 . ASP E 2 226 ? 100.905 154.104 106.995 1.00 79.71  ? 172 ASP C OD2 1 
ATOM   12261 N  N   . LYS E 2 227 ? 100.787 149.136 104.408 1.00 48.16  ? 173 LYS C N   1 
ATOM   12262 C  CA  . LYS E 2 227 ? 100.408 147.738 104.317 1.00 49.90  ? 173 LYS C CA  1 
ATOM   12263 C  C   . LYS E 2 227 ? 101.443 146.911 103.576 1.00 49.73  ? 173 LYS C C   1 
ATOM   12264 O  O   . LYS E 2 227 ? 101.122 145.824 103.089 1.00 55.95  ? 173 LYS C O   1 
ATOM   12265 C  CB  . LYS E 2 227 ? 99.044  147.610 103.641 1.00 56.16  ? 173 LYS C CB  1 
ATOM   12266 C  CG  . LYS E 2 227 ? 97.960  148.447 104.290 1.00 62.27  ? 173 LYS C CG  1 
ATOM   12267 C  CD  . LYS E 2 227 ? 97.868  148.154 105.775 1.00 69.52  ? 173 LYS C CD  1 
ATOM   12268 C  CE  . LYS E 2 227 ? 96.812  149.009 106.450 1.00 71.99  ? 173 LYS C CE  1 
ATOM   12269 N  NZ  . LYS E 2 227 ? 95.460  148.790 105.869 1.00 78.68  ? 173 LYS C NZ  1 
ATOM   12270 N  N   . ALA E 2 228 ? 102.670 147.415 103.463 1.00 44.64  ? 174 ALA C N   1 
ATOM   12271 C  CA  . ALA E 2 228 ? 103.711 146.700 102.740 1.00 36.38  ? 174 ALA C CA  1 
ATOM   12272 C  C   . ALA E 2 228 ? 104.271 145.544 103.551 1.00 38.88  ? 174 ALA C C   1 
ATOM   12273 O  O   . ALA E 2 228 ? 104.589 144.492 102.990 1.00 43.70  ? 174 ALA C O   1 
ATOM   12274 C  CB  . ALA E 2 228 ? 104.828 147.661 102.349 1.00 33.27  ? 174 ALA C CB  1 
ATOM   12275 N  N   . VAL E 2 229 ? 104.400 145.713 104.862 1.00 36.69  ? 175 VAL C N   1 
ATOM   12276 C  CA  . VAL E 2 229 ? 105.007 144.715 105.732 1.00 34.46  ? 175 VAL C CA  1 
ATOM   12277 C  C   . VAL E 2 229 ? 103.913 144.064 106.560 1.00 39.65  ? 175 VAL C C   1 
ATOM   12278 O  O   . VAL E 2 229 ? 103.158 144.752 107.256 1.00 46.96  ? 175 VAL C O   1 
ATOM   12279 C  CB  . VAL E 2 229 ? 106.085 145.337 106.633 1.00 33.48  ? 175 VAL C CB  1 
ATOM   12280 C  CG1 . VAL E 2 229 ? 106.633 144.305 107.585 1.00 34.55  ? 175 VAL C CG1 1 
ATOM   12281 C  CG2 . VAL E 2 229 ? 107.189 145.899 105.784 1.00 26.60  ? 175 VAL C CG2 1 
ATOM   12282 N  N   . THR E 2 230 ? 103.828 142.740 106.486 1.00 37.05  ? 176 THR C N   1 
ATOM   12283 C  CA  . THR E 2 230 ? 102.777 141.981 107.142 1.00 40.93  ? 176 THR C CA  1 
ATOM   12284 C  C   . THR E 2 230 ? 103.389 140.877 107.989 1.00 39.84  ? 176 THR C C   1 
ATOM   12285 O  O   . THR E 2 230 ? 104.563 140.531 107.851 1.00 36.92  ? 176 THR C O   1 
ATOM   12286 C  CB  . THR E 2 230 ? 101.801 141.381 106.126 1.00 40.29  ? 176 THR C CB  1 
ATOM   12287 O  OG1 . THR E 2 230 ? 102.523 140.586 105.182 1.00 40.86  ? 176 THR C OG1 1 
ATOM   12288 C  CG2 . THR E 2 230 ? 101.068 142.478 105.389 1.00 40.64  ? 176 THR C CG2 1 
ATOM   12289 N  N   . GLY E 2 231 ? 102.572 140.324 108.879 1.00 41.79  ? 177 GLY C N   1 
ATOM   12290 C  CA  . GLY E 2 231 ? 103.007 139.276 109.769 1.00 43.61  ? 177 GLY C CA  1 
ATOM   12291 C  C   . GLY E 2 231 ? 103.692 139.744 111.030 1.00 46.88  ? 177 GLY C C   1 
ATOM   12292 O  O   . GLY E 2 231 ? 104.154 138.903 111.808 1.00 50.02  ? 177 GLY C O   1 
ATOM   12293 N  N   . VAL E 2 232 ? 103.789 141.056 111.252 1.00 48.11  ? 178 VAL C N   1 
ATOM   12294 C  CA  . VAL E 2 232 ? 104.431 141.569 112.457 1.00 52.30  ? 178 VAL C CA  1 
ATOM   12295 C  C   . VAL E 2 232 ? 103.552 141.352 113.679 1.00 54.31  ? 178 VAL C C   1 
ATOM   12296 O  O   . VAL E 2 232 ? 104.058 141.142 114.786 1.00 52.43  ? 178 VAL C O   1 
ATOM   12297 C  CB  . VAL E 2 232 ? 104.781 143.055 112.270 1.00 52.68  ? 178 VAL C CB  1 
ATOM   12298 C  CG1 . VAL E 2 232 ? 105.461 143.608 113.507 1.00 44.83  ? 178 VAL C CG1 1 
ATOM   12299 C  CG2 . VAL E 2 232 ? 105.667 143.235 111.061 1.00 47.83  ? 178 VAL C CG2 1 
ATOM   12300 N  N   . GLU E 2 233 ? 102.233 141.398 113.506 1.00 59.36  ? 179 GLU C N   1 
ATOM   12301 C  CA  . GLU E 2 233 ? 101.304 141.366 114.628 1.00 60.06  ? 179 GLU C CA  1 
ATOM   12302 C  C   . GLU E 2 233 ? 101.167 139.989 115.263 1.00 60.11  ? 179 GLU C C   1 
ATOM   12303 O  O   . GLU E 2 233 ? 100.524 139.879 116.311 1.00 64.67  ? 179 GLU C O   1 
ATOM   12304 C  CB  . GLU E 2 233 ? 99.932  141.867 114.178 1.00 55.50  ? 179 GLU C CB  1 
ATOM   12305 C  CG  . GLU E 2 233 ? 99.829  143.383 114.042 1.00 66.40  ? 179 GLU C CG  1 
ATOM   12306 C  CD  . GLU E 2 233 ? 100.755 143.954 112.978 1.00 77.44  ? 179 GLU C CD  1 
ATOM   12307 O  OE1 . GLU E 2 233 ? 101.068 143.236 112.006 1.00 72.24  ? 179 GLU C OE1 1 
ATOM   12308 O  OE2 . GLU E 2 233 ? 101.174 145.122 113.119 1.00 78.78  ? 179 GLU C OE2 1 
ATOM   12309 N  N   . ARG E 2 234 ? 101.731 138.946 114.667 1.00 54.67  ? 180 ARG C N   1 
ATOM   12310 C  CA  . ARG E 2 234 ? 101.672 137.600 115.221 1.00 56.28  ? 180 ARG C CA  1 
ATOM   12311 C  C   . ARG E 2 234 ? 103.065 137.073 115.542 1.00 58.71  ? 180 ARG C C   1 
ATOM   12312 O  O   . ARG E 2 234 ? 103.375 135.905 115.313 1.00 62.47  ? 180 ARG C O   1 
ATOM   12313 C  CB  . ARG E 2 234 ? 100.948 136.649 114.274 1.00 57.11  ? 180 ARG C CB  1 
ATOM   12314 C  CG  . ARG E 2 234 ? 101.513 136.618 112.874 1.00 61.01  ? 180 ARG C CG  1 
ATOM   12315 C  CD  . ARG E 2 234 ? 101.235 135.285 112.203 1.00 62.28  ? 180 ARG C CD  1 
ATOM   12316 N  NE  . ARG E 2 234 ? 101.672 135.276 110.813 1.00 71.53  ? 180 ARG C NE  1 
ATOM   12317 C  CZ  . ARG E 2 234 ? 102.933 135.152 110.424 1.00 72.48  ? 180 ARG C CZ  1 
ATOM   12318 N  NH1 . ARG E 2 234 ? 103.918 135.031 111.300 1.00 66.50  ? 180 ARG C NH1 1 
ATOM   12319 N  NH2 . ARG E 2 234 ? 103.215 135.155 109.125 1.00 66.79  ? 180 ARG C NH2 1 
ATOM   12320 N  N   . ILE E 2 235 ? 103.918 137.929 116.092 1.00 56.90  ? 181 ILE C N   1 
ATOM   12321 C  CA  . ILE E 2 235 ? 105.275 137.558 116.471 1.00 54.71  ? 181 ILE C CA  1 
ATOM   12322 C  C   . ILE E 2 235 ? 105.343 137.524 117.988 1.00 61.39  ? 181 ILE C C   1 
ATOM   12323 O  O   . ILE E 2 235 ? 105.009 138.511 118.653 1.00 65.04  ? 181 ILE C O   1 
ATOM   12324 C  CB  . ILE E 2 235 ? 106.312 138.533 115.899 1.00 50.32  ? 181 ILE C CB  1 
ATOM   12325 C  CG1 . ILE E 2 235 ? 106.428 138.358 114.391 1.00 49.46  ? 181 ILE C CG1 1 
ATOM   12326 C  CG2 . ILE E 2 235 ? 107.656 138.314 116.555 1.00 45.21  ? 181 ILE C CG2 1 
ATOM   12327 C  CD1 . ILE E 2 235 ? 107.299 139.387 113.754 1.00 45.10  ? 181 ILE C CD1 1 
ATOM   12328 N  N   . GLU E 2 236 ? 105.769 136.392 118.535 1.00 60.82  ? 182 GLU C N   1 
ATOM   12329 C  CA  . GLU E 2 236 ? 105.919 136.222 119.971 1.00 57.04  ? 182 GLU C CA  1 
ATOM   12330 C  C   . GLU E 2 236 ? 107.388 136.032 120.312 1.00 48.75  ? 182 GLU C C   1 
ATOM   12331 O  O   . GLU E 2 236 ? 108.055 135.162 119.745 1.00 53.52  ? 182 GLU C O   1 
ATOM   12332 C  CB  . GLU E 2 236 ? 105.107 135.029 120.470 1.00 62.79  ? 182 GLU C CB  1 
ATOM   12333 C  CG  . GLU E 2 236 ? 103.616 135.179 120.284 1.00 74.08  ? 182 GLU C CG  1 
ATOM   12334 C  CD  . GLU E 2 236 ? 102.876 133.905 120.600 1.00 97.52  ? 182 GLU C CD  1 
ATOM   12335 O  OE1 . GLU E 2 236 ? 103.489 133.003 121.207 1.00 99.66  ? 182 GLU C OE1 1 
ATOM   12336 O  OE2 . GLU E 2 236 ? 101.687 133.799 120.238 1.00 105.54 ? 182 GLU C OE2 1 
ATOM   12337 N  N   . LEU E 2 237 ? 107.878 136.837 121.235 1.00 41.67  ? 183 LEU C N   1 
ATOM   12338 C  CA  . LEU E 2 237 ? 109.233 136.772 121.735 1.00 43.62  ? 183 LEU C CA  1 
ATOM   12339 C  C   . LEU E 2 237 ? 109.231 136.367 123.204 1.00 49.35  ? 183 LEU C C   1 
ATOM   12340 O  O   . LEU E 2 237 ? 108.287 136.678 123.935 1.00 53.32  ? 183 LEU C O   1 
ATOM   12341 C  CB  . LEU E 2 237 ? 109.939 138.123 121.576 1.00 45.30  ? 183 LEU C CB  1 
ATOM   12342 C  CG  . LEU E 2 237 ? 110.319 138.541 120.157 1.00 43.32  ? 183 LEU C CG  1 
ATOM   12343 C  CD1 . LEU E 2 237 ? 110.358 140.043 120.017 1.00 43.22  ? 183 LEU C CD1 1 
ATOM   12344 C  CD2 . LEU E 2 237 ? 111.659 137.952 119.802 1.00 35.95  ? 183 LEU C CD2 1 
ATOM   12345 N  N   . PRO E 2 238 ? 110.248 135.634 123.660 1.00 48.32  ? 184 PRO C N   1 
ATOM   12346 C  CA  . PRO E 2 238 ? 110.273 135.238 125.077 1.00 47.37  ? 184 PRO C CA  1 
ATOM   12347 C  C   . PRO E 2 238 ? 110.330 136.407 126.046 1.00 47.63  ? 184 PRO C C   1 
ATOM   12348 O  O   . PRO E 2 238 ? 109.705 136.344 127.109 1.00 48.78  ? 184 PRO C O   1 
ATOM   12349 C  CB  . PRO E 2 238 ? 111.528 134.365 125.165 1.00 44.52  ? 184 PRO C CB  1 
ATOM   12350 C  CG  . PRO E 2 238 ? 111.734 133.872 123.793 1.00 49.40  ? 184 PRO C CG  1 
ATOM   12351 C  CD  . PRO E 2 238 ? 111.326 134.994 122.897 1.00 46.84  ? 184 PRO C CD  1 
ATOM   12352 N  N   . GLN E 2 239 ? 111.047 137.482 125.711 1.00 45.33  ? 185 GLN C N   1 
ATOM   12353 C  CA  . GLN E 2 239 ? 111.250 138.581 126.644 1.00 37.51  ? 185 GLN C CA  1 
ATOM   12354 C  C   . GLN E 2 239 ? 110.581 139.880 126.245 1.00 40.35  ? 185 GLN C C   1 
ATOM   12355 O  O   . GLN E 2 239 ? 110.312 140.702 127.122 1.00 44.68  ? 185 GLN C O   1 
ATOM   12356 C  CB  . GLN E 2 239 ? 112.743 138.871 126.825 1.00 35.99  ? 185 GLN C CB  1 
ATOM   12357 C  CG  . GLN E 2 239 ? 113.473 137.913 127.715 1.00 43.10  ? 185 GLN C CG  1 
ATOM   12358 C  CD  . GLN E 2 239 ? 114.915 138.307 127.912 1.00 54.00  ? 185 GLN C CD  1 
ATOM   12359 O  OE1 . GLN E 2 239 ? 115.227 139.185 128.714 1.00 50.66  ? 185 GLN C OE1 1 
ATOM   12360 N  NE2 . GLN E 2 239 ? 115.809 137.656 127.181 1.00 59.87  ? 185 GLN C NE2 1 
ATOM   12361 N  N   . PHE E 2 240 ? 110.334 140.102 124.964 1.00 39.49  ? 186 PHE C N   1 
ATOM   12362 C  CA  . PHE E 2 240 ? 109.876 141.392 124.483 1.00 35.10  ? 186 PHE C CA  1 
ATOM   12363 C  C   . PHE E 2 240 ? 108.488 141.274 123.878 1.00 39.42  ? 186 PHE C C   1 
ATOM   12364 O  O   . PHE E 2 240 ? 107.958 140.183 123.672 1.00 44.43  ? 186 PHE C O   1 
ATOM   12365 C  CB  . PHE E 2 240 ? 110.843 141.966 123.445 1.00 34.86  ? 186 PHE C CB  1 
ATOM   12366 C  CG  . PHE E 2 240 ? 112.205 142.251 123.981 1.00 38.31  ? 186 PHE C CG  1 
ATOM   12367 C  CD1 . PHE E 2 240 ? 113.173 141.273 123.991 1.00 36.19  ? 186 PHE C CD1 1 
ATOM   12368 C  CD2 . PHE E 2 240 ? 112.524 143.503 124.463 1.00 37.15  ? 186 PHE C CD2 1 
ATOM   12369 C  CE1 . PHE E 2 240 ? 114.421 141.533 124.474 1.00 38.28  ? 186 PHE C CE1 1 
ATOM   12370 C  CE2 . PHE E 2 240 ? 113.775 143.765 124.953 1.00 37.50  ? 186 PHE C CE2 1 
ATOM   12371 C  CZ  . PHE E 2 240 ? 114.723 142.779 124.959 1.00 38.61  ? 186 PHE C CZ  1 
ATOM   12372 N  N   . SER E 2 241 ? 107.897 142.430 123.607 1.00 40.14  ? 187 SER C N   1 
ATOM   12373 C  CA  . SER E 2 241 ? 106.688 142.529 122.809 1.00 42.32  ? 187 SER C CA  1 
ATOM   12374 C  C   . SER E 2 241 ? 106.878 143.669 121.826 1.00 42.47  ? 187 SER C C   1 
ATOM   12375 O  O   . SER E 2 241 ? 107.517 144.671 122.150 1.00 42.27  ? 187 SER C O   1 
ATOM   12376 C  CB  . SER E 2 241 ? 105.448 142.758 123.675 1.00 42.96  ? 187 SER C CB  1 
ATOM   12377 O  OG  . SER E 2 241 ? 105.566 143.947 124.428 1.00 47.33  ? 187 SER C OG  1 
ATOM   12378 N  N   . ILE E 2 242 ? 106.348 143.501 120.619 1.00 41.59  ? 188 ILE C N   1 
ATOM   12379 C  CA  . ILE E 2 242 ? 106.513 144.485 119.556 1.00 39.32  ? 188 ILE C CA  1 
ATOM   12380 C  C   . ILE E 2 242 ? 105.391 145.505 119.710 1.00 40.91  ? 188 ILE C C   1 
ATOM   12381 O  O   . ILE E 2 242 ? 104.249 145.255 119.334 1.00 45.08  ? 188 ILE C O   1 
ATOM   12382 C  CB  . ILE E 2 242 ? 106.513 143.831 118.176 1.00 39.04  ? 188 ILE C CB  1 
ATOM   12383 C  CG1 . ILE E 2 242 ? 107.664 142.833 118.077 1.00 41.14  ? 188 ILE C CG1 1 
ATOM   12384 C  CG2 . ILE E 2 242 ? 106.637 144.884 117.098 1.00 40.48  ? 188 ILE C CG2 1 
ATOM   12385 C  CD1 . ILE E 2 242 ? 107.666 142.025 116.821 1.00 48.84  ? 188 ILE C CD1 1 
ATOM   12386 N  N   . VAL E 2 243 ? 105.727 146.662 120.279 1.00 42.52  ? 189 VAL C N   1 
ATOM   12387 C  CA  . VAL E 2 243 ? 104.739 147.707 120.516 1.00 40.43  ? 189 VAL C CA  1 
ATOM   12388 C  C   . VAL E 2 243 ? 104.300 148.347 119.207 1.00 45.83  ? 189 VAL C C   1 
ATOM   12389 O  O   . VAL E 2 243 ? 103.119 148.654 119.015 1.00 49.93  ? 189 VAL C O   1 
ATOM   12390 C  CB  . VAL E 2 243 ? 105.304 148.754 121.489 1.00 43.58  ? 189 VAL C CB  1 
ATOM   12391 C  CG1 . VAL E 2 243 ? 104.324 149.886 121.662 1.00 48.77  ? 189 VAL C CG1 1 
ATOM   12392 C  CG2 . VAL E 2 243 ? 105.601 148.116 122.815 1.00 45.58  ? 189 VAL C CG2 1 
ATOM   12393 N  N   . GLU E 2 244 ? 105.241 148.570 118.295 1.00 43.06  ? 190 GLU C N   1 
ATOM   12394 C  CA  . GLU E 2 244 ? 104.957 149.313 117.080 1.00 41.07  ? 190 GLU C CA  1 
ATOM   12395 C  C   . GLU E 2 244 ? 105.990 148.950 116.025 1.00 41.11  ? 190 GLU C C   1 
ATOM   12396 O  O   . GLU E 2 244 ? 107.095 148.520 116.351 1.00 44.68  ? 190 GLU C O   1 
ATOM   12397 C  CB  . GLU E 2 244 ? 104.977 150.818 117.356 1.00 41.57  ? 190 GLU C CB  1 
ATOM   12398 C  CG  . GLU E 2 244 ? 104.353 151.670 116.282 1.00 50.96  ? 190 GLU C CG  1 
ATOM   12399 C  CD  . GLU E 2 244 ? 104.516 153.145 116.561 1.00 68.09  ? 190 GLU C CD  1 
ATOM   12400 O  OE1 . GLU E 2 244 ? 105.020 153.490 117.647 1.00 72.64  ? 190 GLU C OE1 1 
ATOM   12401 O  OE2 . GLU E 2 244 ? 104.146 153.963 115.695 1.00 77.68  ? 190 GLU C OE2 1 
ATOM   12402 N  N   . HIS E 2 245 ? 105.615 149.120 114.762 1.00 38.78  ? 191 HIS C N   1 
ATOM   12403 C  CA  . HIS E 2 245 ? 106.558 149.077 113.656 1.00 36.40  ? 191 HIS C CA  1 
ATOM   12404 C  C   . HIS E 2 245 ? 106.278 150.260 112.741 1.00 38.43  ? 191 HIS C C   1 
ATOM   12405 O  O   . HIS E 2 245 ? 105.207 150.868 112.785 1.00 43.74  ? 191 HIS C O   1 
ATOM   12406 C  CB  . HIS E 2 245 ? 106.495 147.749 112.883 1.00 39.03  ? 191 HIS C CB  1 
ATOM   12407 C  CG  . HIS E 2 245 ? 105.395 147.678 111.873 1.00 43.14  ? 191 HIS C CG  1 
ATOM   12408 N  ND1 . HIS E 2 245 ? 104.071 147.541 112.222 1.00 46.09  ? 191 HIS C ND1 1 
ATOM   12409 C  CD2 . HIS E 2 245 ? 105.425 147.713 110.521 1.00 42.09  ? 191 HIS C CD2 1 
ATOM   12410 C  CE1 . HIS E 2 245 ? 103.332 147.504 111.129 1.00 47.30  ? 191 HIS C CE1 1 
ATOM   12411 N  NE2 . HIS E 2 245 ? 104.130 147.607 110.083 1.00 43.35  ? 191 HIS C NE2 1 
ATOM   12412 N  N   . ARG E 2 246 ? 107.269 150.597 111.924 1.00 37.64  ? 192 ARG C N   1 
ATOM   12413 C  CA  . ARG E 2 246 ? 107.245 151.833 111.162 1.00 36.90  ? 192 ARG C CA  1 
ATOM   12414 C  C   . ARG E 2 246 ? 108.016 151.647 109.863 1.00 39.82  ? 192 ARG C C   1 
ATOM   12415 O  O   . ARG E 2 246 ? 109.018 150.928 109.818 1.00 42.86  ? 192 ARG C O   1 
ATOM   12416 C  CB  . ARG E 2 246 ? 107.840 152.974 111.989 1.00 40.34  ? 192 ARG C CB  1 
ATOM   12417 C  CG  . ARG E 2 246 ? 107.508 154.356 111.504 1.00 47.81  ? 192 ARG C CG  1 
ATOM   12418 C  CD  . ARG E 2 246 ? 107.849 155.382 112.564 1.00 52.20  ? 192 ARG C CD  1 
ATOM   12419 N  NE  . ARG E 2 246 ? 107.056 155.205 113.774 1.00 52.88  ? 192 ARG C NE  1 
ATOM   12420 C  CZ  . ARG E 2 246 ? 107.192 155.941 114.868 1.00 56.77  ? 192 ARG C CZ  1 
ATOM   12421 N  NH1 . ARG E 2 246 ? 108.091 156.907 114.943 1.00 53.73  ? 192 ARG C NH1 1 
ATOM   12422 N  NH2 . ARG E 2 246 ? 106.411 155.699 115.914 1.00 55.58  ? 192 ARG C NH2 1 
ATOM   12423 N  N   . LEU E 2 247 ? 107.546 152.319 108.811 1.00 37.33  ? 193 LEU C N   1 
ATOM   12424 C  CA  . LEU E 2 247 ? 108.138 152.259 107.481 1.00 33.43  ? 193 LEU C CA  1 
ATOM   12425 C  C   . LEU E 2 247 ? 108.590 153.650 107.064 1.00 34.14  ? 193 LEU C C   1 
ATOM   12426 O  O   . LEU E 2 247 ? 107.808 154.601 107.130 1.00 42.93  ? 193 LEU C O   1 
ATOM   12427 C  CB  . LEU E 2 247 ? 107.137 151.713 106.464 1.00 31.79  ? 193 LEU C CB  1 
ATOM   12428 C  CG  . LEU E 2 247 ? 106.578 150.315 106.702 1.00 28.52  ? 193 LEU C CG  1 
ATOM   12429 C  CD1 . LEU E 2 247 ? 105.555 149.981 105.652 1.00 27.57  ? 193 LEU C CD1 1 
ATOM   12430 C  CD2 . LEU E 2 247 ? 107.688 149.302 106.689 1.00 28.56  ? 193 LEU C CD2 1 
ATOM   12431 N  N   . VAL E 2 248 ? 109.840 153.767 106.621 1.00 30.40  ? 194 VAL C N   1 
ATOM   12432 C  CA  . VAL E 2 248 ? 110.436 155.057 106.285 1.00 33.30  ? 194 VAL C CA  1 
ATOM   12433 C  C   . VAL E 2 248 ? 111.160 154.949 104.949 1.00 34.34  ? 194 VAL C C   1 
ATOM   12434 O  O   . VAL E 2 248 ? 111.728 153.902 104.626 1.00 35.65  ? 194 VAL C O   1 
ATOM   12435 C  CB  . VAL E 2 248 ? 111.398 155.533 107.397 1.00 34.53  ? 194 VAL C CB  1 
ATOM   12436 C  CG1 . VAL E 2 248 ? 112.203 156.723 106.951 1.00 39.25  ? 194 VAL C CG1 1 
ATOM   12437 C  CG2 . VAL E 2 248 ? 110.623 155.884 108.639 1.00 37.19  ? 194 VAL C CG2 1 
ATOM   12438 N  N   . SER E 2 249 ? 111.127 156.024 104.166 1.00 33.25  ? 195 SER C N   1 
ATOM   12439 C  CA  . SER E 2 249 ? 111.834 156.101 102.896 1.00 35.37  ? 195 SER C CA  1 
ATOM   12440 C  C   . SER E 2 249 ? 112.648 157.384 102.837 1.00 43.56  ? 195 SER C C   1 
ATOM   12441 O  O   . SER E 2 249 ? 112.160 158.445 103.231 1.00 57.50  ? 195 SER C O   1 
ATOM   12442 C  CB  . SER E 2 249 ? 110.853 156.052 101.732 1.00 38.61  ? 195 SER C CB  1 
ATOM   12443 O  OG  . SER E 2 249 ? 111.524 156.222 100.500 1.00 48.13  ? 195 SER C OG  1 
ATOM   12444 N  N   . ARG E 2 250 ? 113.876 157.300 102.329 1.00 41.98  ? 196 ARG C N   1 
ATOM   12445 C  CA  . ARG E 2 250 ? 114.727 158.484 102.267 1.00 41.37  ? 196 ARG C CA  1 
ATOM   12446 C  C   . ARG E 2 250 ? 115.865 158.262 101.278 1.00 41.36  ? 196 ARG C C   1 
ATOM   12447 O  O   . ARG E 2 250 ? 115.931 157.245 100.585 1.00 44.66  ? 196 ARG C O   1 
ATOM   12448 C  CB  . ARG E 2 250 ? 115.264 158.843 103.652 1.00 45.99  ? 196 ARG C CB  1 
ATOM   12449 C  CG  . ARG E 2 250 ? 116.076 157.755 104.318 1.00 44.42  ? 196 ARG C CG  1 
ATOM   12450 C  CD  . ARG E 2 250 ? 116.489 158.189 105.706 1.00 51.64  ? 196 ARG C CD  1 
ATOM   12451 N  NE  . ARG E 2 250 ? 117.231 159.442 105.675 1.00 61.47  ? 196 ARG C NE  1 
ATOM   12452 C  CZ  . ARG E 2 250 ? 117.360 160.259 106.710 1.00 59.29  ? 196 ARG C CZ  1 
ATOM   12453 N  NH1 . ARG E 2 250 ? 116.803 159.988 107.875 1.00 59.47  ? 196 ARG C NH1 1 
ATOM   12454 N  NH2 . ARG E 2 250 ? 118.052 161.382 106.567 1.00 59.13  ? 196 ARG C NH2 1 
ATOM   12455 N  N   . ASN E 2 251 ? 116.756 159.249 101.208 1.00 41.78  ? 197 ASN C N   1 
ATOM   12456 C  CA  . ASN E 2 251 ? 117.962 159.210 100.393 1.00 41.43  ? 197 ASN C CA  1 
ATOM   12457 C  C   . ASN E 2 251 ? 119.168 159.441 101.289 1.00 43.40  ? 197 ASN C C   1 
ATOM   12458 O  O   . ASN E 2 251 ? 119.146 160.320 102.154 1.00 50.09  ? 197 ASN C O   1 
ATOM   12459 C  CB  . ASN E 2 251 ? 117.942 160.276 99.293  1.00 37.73  ? 197 ASN C CB  1 
ATOM   12460 C  CG  . ASN E 2 251 ? 116.950 159.973 98.194  1.00 45.56  ? 197 ASN C CG  1 
ATOM   12461 O  OD1 . ASN E 2 251 ? 116.553 158.829 97.994  1.00 50.92  ? 197 ASN C OD1 1 
ATOM   12462 N  ND2 . ASN E 2 251 ? 116.553 161.003 97.463  1.00 46.61  ? 197 ASN C ND2 1 
ATOM   12463 N  N   . VAL E 2 252 ? 120.224 158.663 101.075 1.00 35.14  ? 198 VAL C N   1 
ATOM   12464 C  CA  . VAL E 2 252 ? 121.418 158.704 101.909 1.00 32.83  ? 198 VAL C CA  1 
ATOM   12465 C  C   . VAL E 2 252 ? 122.614 158.999 101.020 1.00 37.59  ? 198 VAL C C   1 
ATOM   12466 O  O   . VAL E 2 252 ? 122.803 158.339 99.997  1.00 43.31  ? 198 VAL C O   1 
ATOM   12467 C  CB  . VAL E 2 252 ? 121.609 157.382 102.670 1.00 34.71  ? 198 VAL C CB  1 
ATOM   12468 C  CG1 . VAL E 2 252 ? 122.922 157.378 103.382 1.00 38.42  ? 198 VAL C CG1 1 
ATOM   12469 C  CG2 . VAL E 2 252 ? 120.486 157.180 103.655 1.00 34.85  ? 198 VAL C CG2 1 
ATOM   12470 N  N   . VAL E 2 253 ? 123.427 159.976 101.407 1.00 35.21  ? 199 VAL C N   1 
ATOM   12471 C  CA  . VAL E 2 253 ? 124.496 160.484 100.555 1.00 33.17  ? 199 VAL C CA  1 
ATOM   12472 C  C   . VAL E 2 253 ? 125.827 159.954 101.068 1.00 39.38  ? 199 VAL C C   1 
ATOM   12473 O  O   . VAL E 2 253 ? 126.174 160.156 102.236 1.00 44.84  ? 199 VAL C O   1 
ATOM   12474 C  CB  . VAL E 2 253 ? 124.499 162.017 100.507 1.00 28.59  ? 199 VAL C CB  1 
ATOM   12475 C  CG1 . VAL E 2 253 ? 125.302 162.503 99.330  1.00 28.59  ? 199 VAL C CG1 1 
ATOM   12476 C  CG2 . VAL E 2 253 ? 123.090 162.540 100.431 1.00 29.97  ? 199 VAL C CG2 1 
ATOM   12477 N  N   . PHE E 2 254 ? 126.567 159.274 100.198 1.00 41.48  ? 200 PHE C N   1 
ATOM   12478 C  CA  . PHE E 2 254 ? 127.940 158.859 100.431 1.00 38.55  ? 200 PHE C CA  1 
ATOM   12479 C  C   . PHE E 2 254 ? 128.859 159.603 99.471  1.00 46.77  ? 200 PHE C C   1 
ATOM   12480 O  O   . PHE E 2 254 ? 128.414 160.357 98.600  1.00 48.28  ? 200 PHE C O   1 
ATOM   12481 C  CB  . PHE E 2 254 ? 128.105 157.354 100.237 1.00 38.10  ? 200 PHE C CB  1 
ATOM   12482 C  CG  . PHE E 2 254 ? 127.312 156.520 101.184 1.00 44.94  ? 200 PHE C CG  1 
ATOM   12483 C  CD1 . PHE E 2 254 ? 126.017 156.161 100.886 1.00 46.11  ? 200 PHE C CD1 1 
ATOM   12484 C  CD2 . PHE E 2 254 ? 127.872 156.067 102.356 1.00 44.45  ? 200 PHE C CD2 1 
ATOM   12485 C  CE1 . PHE E 2 254 ? 125.292 155.378 101.748 1.00 46.54  ? 200 PHE C CE1 1 
ATOM   12486 C  CE2 . PHE E 2 254 ? 127.150 155.283 103.219 1.00 48.61  ? 200 PHE C CE2 1 
ATOM   12487 C  CZ  . PHE E 2 254 ? 125.858 154.940 102.914 1.00 48.74  ? 200 PHE C CZ  1 
ATOM   12488 N  N   . ALA E 2 255 ? 130.160 159.342 99.607  1.00 48.07  ? 201 ALA C N   1 
ATOM   12489 C  CA  . ALA E 2 255 ? 131.147 159.991 98.753  1.00 46.90  ? 201 ALA C CA  1 
ATOM   12490 C  C   . ALA E 2 255 ? 130.951 159.657 97.281  1.00 51.25  ? 201 ALA C C   1 
ATOM   12491 O  O   . ALA E 2 255 ? 131.432 160.402 96.422  1.00 55.63  ? 201 ALA C O   1 
ATOM   12492 C  CB  . ALA E 2 255 ? 132.559 159.603 99.188  1.00 46.38  ? 201 ALA C CB  1 
ATOM   12493 N  N   . THR E 2 256 ? 130.261 158.564 96.970  1.00 47.89  ? 202 THR C N   1 
ATOM   12494 C  CA  . THR E 2 256 ? 129.994 158.173 95.595  1.00 42.99  ? 202 THR C CA  1 
ATOM   12495 C  C   . THR E 2 256 ? 128.637 158.640 95.083  1.00 48.22  ? 202 THR C C   1 
ATOM   12496 O  O   . THR E 2 256 ? 128.323 158.398 93.916  1.00 57.34  ? 202 THR C O   1 
ATOM   12497 C  CB  . THR E 2 256 ? 130.101 156.655 95.451  1.00 43.01  ? 202 THR C CB  1 
ATOM   12498 O  OG1 . THR E 2 256 ? 129.264 156.021 96.423  1.00 49.14  ? 202 THR C OG1 1 
ATOM   12499 C  CG2 . THR E 2 256 ? 131.525 156.209 95.662  1.00 41.44  ? 202 THR C CG2 1 
ATOM   12500 N  N   . GLY E 2 257 ? 127.830 159.304 95.906  1.00 43.89  ? 203 GLY C N   1 
ATOM   12501 C  CA  . GLY E 2 257 ? 126.562 159.826 95.445  1.00 41.03  ? 203 GLY C CA  1 
ATOM   12502 C  C   . GLY E 2 257 ? 125.440 159.479 96.393  1.00 42.67  ? 203 GLY C C   1 
ATOM   12503 O  O   . GLY E 2 257 ? 125.653 158.954 97.488  1.00 47.63  ? 203 GLY C O   1 
ATOM   12504 N  N   . ALA E 2 258 ? 124.216 159.773 95.971  1.00 38.05  ? 204 ALA C N   1 
ATOM   12505 C  CA  . ALA E 2 258 ? 123.034 159.569 96.797  1.00 36.37  ? 204 ALA C CA  1 
ATOM   12506 C  C   . ALA E 2 258 ? 122.346 158.268 96.412  1.00 38.73  ? 204 ALA C C   1 
ATOM   12507 O  O   . ALA E 2 258 ? 122.125 158.005 95.229  1.00 44.38  ? 204 ALA C O   1 
ATOM   12508 C  CB  . ALA E 2 258 ? 122.066 160.742 96.655  1.00 37.05  ? 204 ALA C CB  1 
ATOM   12509 N  N   . TYR E 2 259 ? 121.991 157.469 97.413  1.00 34.00  ? 205 TYR C N   1 
ATOM   12510 C  CA  . TYR E 2 259 ? 121.405 156.161 97.227  1.00 36.14  ? 205 TYR C CA  1 
ATOM   12511 C  C   . TYR E 2 259 ? 120.041 156.086 97.899  1.00 39.22  ? 205 TYR C C   1 
ATOM   12512 O  O   . TYR E 2 259 ? 119.853 156.649 98.982  1.00 39.52  ? 205 TYR C O   1 
ATOM   12513 C  CB  . TYR E 2 259 ? 122.325 155.072 97.802  1.00 37.95  ? 205 TYR C CB  1 
ATOM   12514 C  CG  . TYR E 2 259 ? 123.667 155.001 97.118  1.00 37.18  ? 205 TYR C CG  1 
ATOM   12515 C  CD1 . TYR E 2 259 ? 124.694 155.852 97.481  1.00 39.19  ? 205 TYR C CD1 1 
ATOM   12516 C  CD2 . TYR E 2 259 ? 123.903 154.093 96.103  1.00 36.05  ? 205 TYR C CD2 1 
ATOM   12517 C  CE1 . TYR E 2 259 ? 125.908 155.802 96.855  1.00 41.70  ? 205 TYR C CE1 1 
ATOM   12518 C  CE2 . TYR E 2 259 ? 125.118 154.035 95.474  1.00 36.60  ? 205 TYR C CE2 1 
ATOM   12519 C  CZ  . TYR E 2 259 ? 126.115 154.893 95.852  1.00 42.69  ? 205 TYR C CZ  1 
ATOM   12520 O  OH  . TYR E 2 259 ? 127.335 154.839 95.230  1.00 48.77  ? 205 TYR C OH  1 
ATOM   12521 N  N   . PRO E 2 260 ? 119.072 155.413 97.282  1.00 37.99  ? 206 PRO C N   1 
ATOM   12522 C  CA  . PRO E 2 260 ? 117.762 155.265 97.917  1.00 33.75  ? 206 PRO C CA  1 
ATOM   12523 C  C   . PRO E 2 260 ? 117.837 154.346 99.120  1.00 33.34  ? 206 PRO C C   1 
ATOM   12524 O  O   . PRO E 2 260 ? 118.683 153.454 99.194  1.00 37.63  ? 206 PRO C O   1 
ATOM   12525 C  CB  . PRO E 2 260 ? 116.904 154.660 96.807  1.00 31.18  ? 206 PRO C CB  1 
ATOM   12526 C  CG  . PRO E 2 260 ? 117.868 153.921 95.979  1.00 29.79  ? 206 PRO C CG  1 
ATOM   12527 C  CD  . PRO E 2 260 ? 119.120 154.737 95.978  1.00 34.43  ? 206 PRO C CD  1 
ATOM   12528 N  N   . ARG E 2 261 ? 116.934 154.566 100.068 1.00 31.33  ? 207 ARG C N   1 
ATOM   12529 C  CA  . ARG E 2 261 ? 116.970 153.815 101.311 1.00 30.65  ? 207 ARG C CA  1 
ATOM   12530 C  C   . ARG E 2 261 ? 115.554 153.598 101.807 1.00 34.96  ? 207 ARG C C   1 
ATOM   12531 O  O   . ARG E 2 261 ? 114.744 154.528 101.810 1.00 43.13  ? 207 ARG C O   1 
ATOM   12532 C  CB  . ARG E 2 261 ? 117.793 154.556 102.367 1.00 32.79  ? 207 ARG C CB  1 
ATOM   12533 C  CG  . ARG E 2 261 ? 117.623 154.031 103.770 1.00 34.37  ? 207 ARG C CG  1 
ATOM   12534 C  CD  . ARG E 2 261 ? 118.507 152.841 104.021 1.00 35.73  ? 207 ARG C CD  1 
ATOM   12535 N  NE  . ARG E 2 261 ? 119.910 153.223 104.045 1.00 39.50  ? 207 ARG C NE  1 
ATOM   12536 C  CZ  . ARG E 2 261 ? 120.547 153.648 105.125 1.00 35.42  ? 207 ARG C CZ  1 
ATOM   12537 N  NH1 . ARG E 2 261 ? 119.936 153.750 106.290 1.00 36.44  ? 207 ARG C NH1 1 
ATOM   12538 N  NH2 . ARG E 2 261 ? 121.831 153.971 105.034 1.00 33.14  ? 207 ARG C NH2 1 
ATOM   12539 N  N   . LEU E 2 262 ? 115.270 152.371 102.224 1.00 29.56  ? 208 LEU C N   1 
ATOM   12540 C  CA  . LEU E 2 262 ? 114.055 152.037 102.942 1.00 26.12  ? 208 LEU C CA  1 
ATOM   12541 C  C   . LEU E 2 262 ? 114.427 151.547 104.334 1.00 27.25  ? 208 LEU C C   1 
ATOM   12542 O  O   . LEU E 2 262 ? 115.506 150.994 104.543 1.00 29.99  ? 208 LEU C O   1 
ATOM   12543 C  CB  . LEU E 2 262 ? 113.244 150.972 102.208 1.00 26.43  ? 208 LEU C CB  1 
ATOM   12544 C  CG  . LEU E 2 262 ? 112.785 151.221 100.772 1.00 26.27  ? 208 LEU C CG  1 
ATOM   12545 C  CD1 . LEU E 2 262 ? 111.874 150.102 100.355 1.00 24.67  ? 208 LEU C CD1 1 
ATOM   12546 C  CD2 . LEU E 2 262 ? 112.074 152.541 100.624 1.00 23.57  ? 208 LEU C CD2 1 
ATOM   12547 N  N   . SER E 2 263 ? 113.545 151.784 105.295 1.00 27.43  ? 209 SER C N   1 
ATOM   12548 C  CA  . SER E 2 263 ? 113.794 151.394 106.675 1.00 27.89  ? 209 SER C CA  1 
ATOM   12549 C  C   . SER E 2 263 ? 112.540 150.779 107.260 1.00 32.29  ? 209 SER C C   1 
ATOM   12550 O  O   . SER E 2 263 ? 111.452 151.347 107.134 1.00 33.45  ? 209 SER C O   1 
ATOM   12551 C  CB  . SER E 2 263 ? 114.217 152.587 107.534 1.00 32.02  ? 209 SER C CB  1 
ATOM   12552 O  OG  . SER E 2 263 ? 115.500 153.055 107.179 1.00 43.33  ? 209 SER C OG  1 
ATOM   12553 N  N   . LEU E 2 264 ? 112.702 149.627 107.904 1.00 30.41  ? 210 LEU C N   1 
ATOM   12554 C  CA  . LEU E 2 264 ? 111.635 148.982 108.661 1.00 30.89  ? 210 LEU C CA  1 
ATOM   12555 C  C   . LEU E 2 264 ? 112.078 148.916 110.114 1.00 36.16  ? 210 LEU C C   1 
ATOM   12556 O  O   . LEU E 2 264 ? 113.055 148.238 110.430 1.00 43.28  ? 210 LEU C O   1 
ATOM   12557 C  CB  . LEU E 2 264 ? 111.347 147.589 108.112 1.00 29.47  ? 210 LEU C CB  1 
ATOM   12558 C  CG  . LEU E 2 264 ? 110.606 146.643 109.052 1.00 32.30  ? 210 LEU C CG  1 
ATOM   12559 C  CD1 . LEU E 2 264 ? 109.176 147.083 109.229 1.00 31.65  ? 210 LEU C CD1 1 
ATOM   12560 C  CD2 . LEU E 2 264 ? 110.671 145.236 108.517 1.00 31.62  ? 210 LEU C CD2 1 
ATOM   12561 N  N   . SER E 2 265 ? 111.379 149.613 111.002 1.00 32.63  ? 211 SER C N   1 
ATOM   12562 C  CA  . SER E 2 265 ? 111.782 149.669 112.400 1.00 32.89  ? 211 SER C CA  1 
ATOM   12563 C  C   . SER E 2 265 ? 110.711 149.069 113.296 1.00 35.40  ? 211 SER C C   1 
ATOM   12564 O  O   . SER E 2 265 ? 109.520 149.202 113.022 1.00 41.22  ? 211 SER C O   1 
ATOM   12565 C  CB  . SER E 2 265 ? 112.074 151.100 112.833 1.00 37.49  ? 211 SER C CB  1 
ATOM   12566 O  OG  . SER E 2 265 ? 110.972 151.943 112.578 1.00 48.87  ? 211 SER C OG  1 
ATOM   12567 N  N   . PHE E 2 266 ? 111.146 148.401 114.359 1.00 35.26  ? 212 PHE C N   1 
ATOM   12568 C  CA  . PHE E 2 266 ? 110.274 147.897 115.407 1.00 35.86  ? 212 PHE C CA  1 
ATOM   12569 C  C   . PHE E 2 266 ? 110.671 148.523 116.733 1.00 35.96  ? 212 PHE C C   1 
ATOM   12570 O  O   . PHE E 2 266 ? 111.849 148.792 116.978 1.00 41.90  ? 212 PHE C O   1 
ATOM   12571 C  CB  . PHE E 2 266 ? 110.351 146.374 115.570 1.00 35.97  ? 212 PHE C CB  1 
ATOM   12572 C  CG  . PHE E 2 266 ? 110.481 145.616 114.289 1.00 39.96  ? 212 PHE C CG  1 
ATOM   12573 C  CD1 . PHE E 2 266 ? 109.367 145.158 113.621 1.00 40.30  ? 212 PHE C CD1 1 
ATOM   12574 C  CD2 . PHE E 2 266 ? 111.727 145.327 113.775 1.00 42.38  ? 212 PHE C CD2 1 
ATOM   12575 C  CE1 . PHE E 2 266 ? 109.494 144.451 112.449 1.00 45.41  ? 212 PHE C CE1 1 
ATOM   12576 C  CE2 . PHE E 2 266 ? 111.859 144.625 112.607 1.00 45.06  ? 212 PHE C CE2 1 
ATOM   12577 C  CZ  . PHE E 2 266 ? 110.742 144.182 111.943 1.00 46.24  ? 212 PHE C CZ  1 
ATOM   12578 N  N   . ARG E 2 267 ? 109.688 148.732 117.598 1.00 35.00  ? 213 ARG C N   1 
ATOM   12579 C  CA  . ARG E 2 267 ? 109.931 149.148 118.972 1.00 36.28  ? 213 ARG C CA  1 
ATOM   12580 C  C   . ARG E 2 267 ? 109.589 147.994 119.901 1.00 36.42  ? 213 ARG C C   1 
ATOM   12581 O  O   . ARG E 2 267 ? 108.436 147.560 119.957 1.00 40.46  ? 213 ARG C O   1 
ATOM   12582 C  CB  . ARG E 2 267 ? 109.117 150.389 119.329 1.00 43.09  ? 213 ARG C CB  1 
ATOM   12583 C  CG  . ARG E 2 267 ? 109.694 151.148 120.502 1.00 47.55  ? 213 ARG C CG  1 
ATOM   12584 C  CD  . ARG E 2 267 ? 109.129 152.546 120.623 1.00 49.79  ? 213 ARG C CD  1 
ATOM   12585 N  NE  . ARG E 2 267 ? 107.729 152.544 121.026 1.00 61.49  ? 213 ARG C NE  1 
ATOM   12586 C  CZ  . ARG E 2 267 ? 106.732 152.985 120.274 1.00 67.89  ? 213 ARG C CZ  1 
ATOM   12587 N  NH1 . ARG E 2 267 ? 106.946 153.489 119.071 1.00 67.50  ? 213 ARG C NH1 1 
ATOM   12588 N  NH2 . ARG E 2 267 ? 105.490 152.925 120.743 1.00 64.71  ? 213 ARG C NH2 1 
ATOM   12589 N  N   . LEU E 2 268 ? 110.587 147.505 120.626 1.00 36.09  ? 214 LEU C N   1 
ATOM   12590 C  CA  . LEU E 2 268 ? 110.432 146.376 121.531 1.00 36.04  ? 214 LEU C CA  1 
ATOM   12591 C  C   . LEU E 2 268 ? 110.353 146.858 122.970 1.00 40.34  ? 214 LEU C C   1 
ATOM   12592 O  O   . LEU E 2 268 ? 111.102 147.747 123.379 1.00 44.59  ? 214 LEU C O   1 
ATOM   12593 C  CB  . LEU E 2 268 ? 111.597 145.401 121.399 1.00 33.93  ? 214 LEU C CB  1 
ATOM   12594 C  CG  . LEU E 2 268 ? 111.919 144.817 120.034 1.00 36.38  ? 214 LEU C CG  1 
ATOM   12595 C  CD1 . LEU E 2 268 ? 113.040 143.826 120.186 1.00 33.71  ? 214 LEU C CD1 1 
ATOM   12596 C  CD2 . LEU E 2 268 ? 110.708 144.151 119.451 1.00 40.02  ? 214 LEU C CD2 1 
ATOM   12597 N  N   . LYS E 2 269 ? 109.456 146.251 123.737 1.00 41.89  ? 215 LYS C N   1 
ATOM   12598 C  CA  . LYS E 2 269 ? 109.274 146.556 125.147 1.00 42.31  ? 215 LYS C CA  1 
ATOM   12599 C  C   . LYS E 2 269 ? 109.495 145.290 125.957 1.00 44.02  ? 215 LYS C C   1 
ATOM   12600 O  O   . LYS E 2 269 ? 108.873 144.262 125.682 1.00 47.90  ? 215 LYS C O   1 
ATOM   12601 C  CB  . LYS E 2 269 ? 107.877 147.113 125.395 1.00 45.80  ? 215 LYS C CB  1 
ATOM   12602 C  CG  . LYS E 2 269 ? 107.661 147.687 126.765 1.00 47.94  ? 215 LYS C CG  1 
ATOM   12603 C  CD  . LYS E 2 269 ? 106.293 148.325 126.832 1.00 60.89  ? 215 LYS C CD  1 
ATOM   12604 C  CE  . LYS E 2 269 ? 106.167 149.277 128.002 1.00 75.86  ? 215 LYS C CE  1 
ATOM   12605 N  NZ  . LYS E 2 269 ? 104.865 150.005 127.955 1.00 80.25  ? 215 LYS C NZ  1 
ATOM   12606 N  N   . ARG E 2 270 ? 110.374 145.365 126.951 1.00 38.69  ? 216 ARG C N   1 
ATOM   12607 C  CA  . ARG E 2 270 ? 110.738 144.179 127.712 1.00 35.65  ? 216 ARG C CA  1 
ATOM   12608 C  C   . ARG E 2 270 ? 109.620 143.780 128.666 1.00 40.72  ? 216 ARG C C   1 
ATOM   12609 O  O   . ARG E 2 270 ? 108.961 144.631 129.265 1.00 50.41  ? 216 ARG C O   1 
ATOM   12610 C  CB  . ARG E 2 270 ? 112.025 144.425 128.489 1.00 31.93  ? 216 ARG C CB  1 
ATOM   12611 C  CG  . ARG E 2 270 ? 112.703 143.158 128.952 1.00 37.10  ? 216 ARG C CG  1 
ATOM   12612 C  CD  . ARG E 2 270 ? 113.964 143.452 129.727 1.00 41.74  ? 216 ARG C CD  1 
ATOM   12613 N  NE  . ARG E 2 270 ? 114.917 144.231 128.952 1.00 42.13  ? 216 ARG C NE  1 
ATOM   12614 C  CZ  . ARG E 2 270 ? 115.882 143.711 128.209 1.00 40.86  ? 216 ARG C CZ  1 
ATOM   12615 N  NH1 . ARG E 2 270 ? 116.047 142.404 128.108 1.00 36.04  ? 216 ARG C NH1 1 
ATOM   12616 N  NH2 . ARG E 2 270 ? 116.700 144.523 127.550 1.00 43.69  ? 216 ARG C NH2 1 
ATOM   12617 N  N   . ASN E 2 271 ? 109.412 142.473 128.802 1.00 39.69  ? 217 ASN C N   1 
ATOM   12618 C  CA  . ASN E 2 271 ? 108.465 141.923 129.762 1.00 35.14  ? 217 ASN C CA  1 
ATOM   12619 C  C   . ASN E 2 271 ? 109.176 141.725 131.091 1.00 39.63  ? 217 ASN C C   1 
ATOM   12620 O  O   . ASN E 2 271 ? 110.125 140.941 131.180 1.00 41.22  ? 217 ASN C O   1 
ATOM   12621 C  CB  . ASN E 2 271 ? 107.894 140.598 129.265 1.00 32.94  ? 217 ASN C CB  1 
ATOM   12622 C  CG  . ASN E 2 271 ? 107.155 140.743 127.963 1.00 44.17  ? 217 ASN C CG  1 
ATOM   12623 O  OD1 . ASN E 2 271 ? 107.045 141.840 127.426 1.00 48.59  ? 217 ASN C OD1 1 
ATOM   12624 N  ND2 . ASN E 2 271 ? 106.645 139.638 127.442 1.00 40.30  ? 217 ASN C ND2 1 
ATOM   12625 N  N   . ILE E 2 272 ? 108.719 142.434 132.125 1.00 38.79  ? 218 ILE C N   1 
ATOM   12626 C  CA  . ILE E 2 272 ? 109.371 142.352 133.424 1.00 38.25  ? 218 ILE C CA  1 
ATOM   12627 C  C   . ILE E 2 272 ? 109.208 140.993 134.078 1.00 37.68  ? 218 ILE C C   1 
ATOM   12628 O  O   . ILE E 2 272 ? 109.888 140.709 135.067 1.00 39.60  ? 218 ILE C O   1 
ATOM   12629 C  CB  . ILE E 2 272 ? 108.844 143.447 134.370 1.00 35.91  ? 218 ILE C CB  1 
ATOM   12630 C  CG1 . ILE E 2 272 ? 109.922 143.831 135.378 1.00 35.56  ? 218 ILE C CG1 1 
ATOM   12631 C  CG2 . ILE E 2 272 ? 107.603 142.973 135.090 1.00 30.02  ? 218 ILE C CG2 1 
ATOM   12632 C  CD1 . ILE E 2 272 ? 109.443 144.769 136.443 1.00 43.55  ? 218 ILE C CD1 1 
ATOM   12633 N  N   . GLY E 2 273 ? 108.337 140.137 133.547 1.00 33.04  ? 219 GLY C N   1 
ATOM   12634 C  CA  . GLY E 2 273 ? 108.150 138.827 134.141 1.00 27.37  ? 219 GLY C CA  1 
ATOM   12635 C  C   . GLY E 2 273 ? 109.369 137.938 134.019 1.00 29.43  ? 219 GLY C C   1 
ATOM   12636 O  O   . GLY E 2 273 ? 109.476 136.929 134.716 1.00 34.42  ? 219 GLY C O   1 
ATOM   12637 N  N   . TYR E 2 274 ? 110.304 138.298 133.142 1.00 33.04  ? 220 TYR C N   1 
ATOM   12638 C  CA  . TYR E 2 274 ? 111.520 137.510 132.987 1.00 31.41  ? 220 TYR C CA  1 
ATOM   12639 C  C   . TYR E 2 274 ? 112.596 137.953 133.970 1.00 35.43  ? 220 TYR C C   1 
ATOM   12640 O  O   . TYR E 2 274 ? 113.314 137.116 134.519 1.00 40.25  ? 220 TYR C O   1 
ATOM   12641 C  CB  . TYR E 2 274 ? 112.021 137.613 131.549 1.00 38.45  ? 220 TYR C CB  1 
ATOM   12642 C  CG  . TYR E 2 274 ? 113.202 136.732 131.203 1.00 42.39  ? 220 TYR C CG  1 
ATOM   12643 C  CD1 . TYR E 2 274 ? 114.489 137.090 131.567 1.00 47.06  ? 220 TYR C CD1 1 
ATOM   12644 C  CD2 . TYR E 2 274 ? 113.034 135.569 130.473 1.00 46.78  ? 220 TYR C CD2 1 
ATOM   12645 C  CE1 . TYR E 2 274 ? 115.568 136.306 131.244 1.00 48.76  ? 220 TYR C CE1 1 
ATOM   12646 C  CE2 . TYR E 2 274 ? 114.114 134.776 130.142 1.00 55.80  ? 220 TYR C CE2 1 
ATOM   12647 C  CZ  . TYR E 2 274 ? 115.379 135.152 130.531 1.00 54.94  ? 220 TYR C CZ  1 
ATOM   12648 O  OH  . TYR E 2 274 ? 116.463 134.375 130.209 1.00 58.17  ? 220 TYR C OH  1 
ATOM   12649 N  N   . PHE E 2 275 ? 112.745 139.263 134.186 1.00 35.89  ? 221 PHE C N   1 
ATOM   12650 C  CA  . PHE E 2 275 ? 113.685 139.741 135.197 1.00 31.79  ? 221 PHE C CA  1 
ATOM   12651 C  C   . PHE E 2 275 ? 113.265 139.283 136.583 1.00 34.47  ? 221 PHE C C   1 
ATOM   12652 O  O   . PHE E 2 275 ? 114.061 138.704 137.328 1.00 39.00  ? 221 PHE C O   1 
ATOM   12653 C  CB  . PHE E 2 275 ? 113.787 141.261 135.149 1.00 33.84  ? 221 PHE C CB  1 
ATOM   12654 C  CG  . PHE E 2 275 ? 114.360 141.867 136.393 1.00 37.33  ? 221 PHE C CG  1 
ATOM   12655 C  CD1 . PHE E 2 275 ? 115.721 141.865 136.615 1.00 37.66  ? 221 PHE C CD1 1 
ATOM   12656 C  CD2 . PHE E 2 275 ? 113.540 142.450 137.337 1.00 37.68  ? 221 PHE C CD2 1 
ATOM   12657 C  CE1 . PHE E 2 275 ? 116.247 142.423 137.755 1.00 37.57  ? 221 PHE C CE1 1 
ATOM   12658 C  CE2 . PHE E 2 275 ? 114.064 143.004 138.476 1.00 37.01  ? 221 PHE C CE2 1 
ATOM   12659 C  CZ  . PHE E 2 275 ? 115.417 142.992 138.685 1.00 38.06  ? 221 PHE C CZ  1 
ATOM   12660 N  N   . ILE E 2 276 ? 112.016 139.552 136.955 1.00 35.16  ? 222 ILE C N   1 
ATOM   12661 C  CA  . ILE E 2 276 ? 111.427 138.849 138.076 1.00 30.07  ? 222 ILE C CA  1 
ATOM   12662 C  C   . ILE E 2 276 ? 111.511 137.357 137.802 1.00 35.68  ? 222 ILE C C   1 
ATOM   12663 O  O   . ILE E 2 276 ? 111.591 136.919 136.651 1.00 45.69  ? 222 ILE C O   1 
ATOM   12664 C  CB  . ILE E 2 276 ? 109.972 139.299 138.286 1.00 24.93  ? 222 ILE C CB  1 
ATOM   12665 C  CG1 . ILE E 2 276 ? 109.909 140.804 138.499 1.00 30.17  ? 222 ILE C CG1 1 
ATOM   12666 C  CG2 . ILE E 2 276 ? 109.332 138.588 139.454 1.00 25.44  ? 222 ILE C CG2 1 
ATOM   12667 C  CD1 . ILE E 2 276 ? 108.529 141.297 138.788 1.00 34.04  ? 222 ILE C CD1 1 
ATOM   12668 N  N   . LEU E 2 277 ? 111.547 136.567 138.871 1.00 32.60  ? 223 LEU C N   1 
ATOM   12669 C  CA  . LEU E 2 277 ? 111.535 135.111 138.751 1.00 39.33  ? 223 LEU C CA  1 
ATOM   12670 C  C   . LEU E 2 277 ? 112.872 134.580 138.251 1.00 36.57  ? 223 LEU C C   1 
ATOM   12671 O  O   . LEU E 2 277 ? 113.057 133.374 138.116 1.00 47.57  ? 223 LEU C O   1 
ATOM   12672 C  CB  . LEU E 2 277 ? 110.396 134.642 137.837 1.00 36.36  ? 223 LEU C CB  1 
ATOM   12673 C  CG  . LEU E 2 277 ? 109.871 133.218 137.827 1.00 39.18  ? 223 LEU C CG  1 
ATOM   12674 C  CD1 . LEU E 2 277 ? 109.081 132.959 139.087 1.00 49.54  ? 223 LEU C CD1 1 
ATOM   12675 C  CD2 . LEU E 2 277 ? 109.007 133.037 136.611 1.00 35.16  ? 223 LEU C CD2 1 
ATOM   12676 N  N   . GLN E 2 278 ? 113.815 135.474 137.975 1.00 33.44  ? 224 GLN C N   1 
ATOM   12677 C  CA  . GLN E 2 278 ? 115.141 135.072 137.528 1.00 35.59  ? 224 GLN C CA  1 
ATOM   12678 C  C   . GLN E 2 278 ? 116.226 135.759 138.347 1.00 40.87  ? 224 GLN C C   1 
ATOM   12679 O  O   . GLN E 2 278 ? 117.268 135.162 138.629 1.00 45.66  ? 224 GLN C O   1 
ATOM   12680 C  CB  . GLN E 2 278 ? 115.313 135.393 136.047 1.00 40.76  ? 224 GLN C CB  1 
ATOM   12681 C  CG  . GLN E 2 278 ? 116.534 134.783 135.408 1.00 49.86  ? 224 GLN C CG  1 
ATOM   12682 C  CD  . GLN E 2 278 ? 116.283 133.381 134.904 1.00 57.71  ? 224 GLN C CD  1 
ATOM   12683 O  OE1 . GLN E 2 278 ? 117.142 132.508 135.015 1.00 67.79  ? 224 GLN C OE1 1 
ATOM   12684 N  NE2 . GLN E 2 278 ? 115.103 133.157 134.338 1.00 47.05  ? 224 GLN C NE2 1 
ATOM   12685 N  N   . THR E 2 279 ? 115.993 137.013 138.726 1.00 42.35  ? 225 THR C N   1 
ATOM   12686 C  CA  . THR E 2 279 ? 116.978 137.786 139.472 1.00 34.22  ? 225 THR C CA  1 
ATOM   12687 C  C   . THR E 2 279 ? 116.374 138.438 140.710 1.00 36.32  ? 225 THR C C   1 
ATOM   12688 O  O   . THR E 2 279 ? 117.040 138.555 141.740 1.00 46.79  ? 225 THR C O   1 
ATOM   12689 C  CB  . THR E 2 279 ? 117.596 138.852 138.571 1.00 35.46  ? 225 THR C CB  1 
ATOM   12690 O  OG1 . THR E 2 279 ? 117.980 138.258 137.328 1.00 42.07  ? 225 THR C OG1 1 
ATOM   12691 C  CG2 . THR E 2 279 ? 118.816 139.452 139.217 1.00 42.83  ? 225 THR C CG2 1 
ATOM   12692 N  N   . TYR E 2 280 ? 115.118 138.871 140.624 1.00 32.28  ? 226 TYR C N   1 
ATOM   12693 C  CA  . TYR E 2 280 ? 114.515 139.611 141.729 1.00 34.74  ? 226 TYR C CA  1 
ATOM   12694 C  C   . TYR E 2 280 ? 114.066 138.673 142.842 1.00 43.00  ? 226 TYR C C   1 
ATOM   12695 O  O   . TYR E 2 280 ? 114.413 138.868 144.017 1.00 51.02  ? 226 TYR C O   1 
ATOM   12696 C  CB  . TYR E 2 280 ? 113.343 140.438 141.208 1.00 33.79  ? 226 TYR C CB  1 
ATOM   12697 C  CG  . TYR E 2 280 ? 112.876 141.532 142.133 1.00 40.15  ? 226 TYR C CG  1 
ATOM   12698 C  CD1 . TYR E 2 280 ? 113.717 142.571 142.484 1.00 46.44  ? 226 TYR C CD1 1 
ATOM   12699 C  CD2 . TYR E 2 280 ? 111.585 141.542 142.629 1.00 40.23  ? 226 TYR C CD2 1 
ATOM   12700 C  CE1 . TYR E 2 280 ? 113.292 143.581 143.318 1.00 51.90  ? 226 TYR C CE1 1 
ATOM   12701 C  CE2 . TYR E 2 280 ? 111.151 142.548 143.466 1.00 43.46  ? 226 TYR C CE2 1 
ATOM   12702 C  CZ  . TYR E 2 280 ? 112.009 143.563 143.807 1.00 52.56  ? 226 TYR C CZ  1 
ATOM   12703 O  OH  . TYR E 2 280 ? 111.589 144.571 144.637 1.00 59.60  ? 226 TYR C OH  1 
ATOM   12704 N  N   . MET E 2 281 ? 113.280 137.653 142.492 1.00 41.26  ? 227 MET C N   1 
ATOM   12705 C  CA  . MET E 2 281 ? 112.794 136.718 143.505 1.00 40.88  ? 227 MET C CA  1 
ATOM   12706 C  C   . MET E 2 281 ? 113.927 135.987 144.215 1.00 41.50  ? 227 MET C C   1 
ATOM   12707 O  O   . MET E 2 281 ? 113.860 135.847 145.450 1.00 48.54  ? 227 MET C O   1 
ATOM   12708 C  CB  . MET E 2 281 ? 111.790 135.750 142.873 1.00 44.24  ? 227 MET C CB  1 
ATOM   12709 C  CG  . MET E 2 281 ? 110.928 135.022 143.876 1.00 52.88  ? 227 MET C CG  1 
ATOM   12710 S  SD  . MET E 2 281 ? 110.062 136.147 144.991 1.00 100.57 ? 227 MET C SD  1 
ATOM   12711 C  CE  . MET E 2 281 ? 108.987 137.004 143.848 1.00 65.15  ? 227 MET C CE  1 
ATOM   12712 N  N   . PRO E 2 282 ? 114.956 135.471 143.533 1.00 38.15  ? 228 PRO C N   1 
ATOM   12713 C  CA  . PRO E 2 282 ? 116.079 134.884 144.278 1.00 35.11  ? 228 PRO C CA  1 
ATOM   12714 C  C   . PRO E 2 282 ? 116.767 135.850 145.229 1.00 35.96  ? 228 PRO C C   1 
ATOM   12715 O  O   . PRO E 2 282 ? 117.158 135.447 146.332 1.00 41.22  ? 228 PRO C O   1 
ATOM   12716 C  CB  . PRO E 2 282 ? 117.014 134.420 143.158 1.00 33.85  ? 228 PRO C CB  1 
ATOM   12717 C  CG  . PRO E 2 282 ? 116.125 134.130 142.039 1.00 33.66  ? 228 PRO C CG  1 
ATOM   12718 C  CD  . PRO E 2 282 ? 115.070 135.180 142.094 1.00 37.46  ? 228 PRO C CD  1 
ATOM   12719 N  N   . SER E 2 283 ? 116.921 137.116 144.843 1.00 33.17  ? 229 SER C N   1 
ATOM   12720 C  CA  . SER E 2 283 ? 117.555 138.081 145.734 1.00 36.80  ? 229 SER C CA  1 
ATOM   12721 C  C   . SER E 2 283 ? 116.719 138.304 146.984 1.00 38.29  ? 229 SER C C   1 
ATOM   12722 O  O   . SER E 2 283 ? 117.253 138.359 148.101 1.00 43.98  ? 229 SER C O   1 
ATOM   12723 C  CB  . SER E 2 283 ? 117.776 139.398 145.002 1.00 37.43  ? 229 SER C CB  1 
ATOM   12724 O  OG  . SER E 2 283 ? 118.310 139.167 143.717 1.00 44.63  ? 229 SER C OG  1 
ATOM   12725 N  N   . ILE E 2 284 ? 115.403 138.427 146.817 1.00 34.46  ? 230 ILE C N   1 
ATOM   12726 C  CA  . ILE E 2 284 ? 114.537 138.601 147.978 1.00 36.76  ? 230 ILE C CA  1 
ATOM   12727 C  C   . ILE E 2 284 ? 114.604 137.377 148.884 1.00 38.05  ? 230 ILE C C   1 
ATOM   12728 O  O   . ILE E 2 284 ? 114.680 137.501 150.115 1.00 42.93  ? 230 ILE C O   1 
ATOM   12729 C  CB  . ILE E 2 284 ? 113.100 138.909 147.528 1.00 41.31  ? 230 ILE C CB  1 
ATOM   12730 C  CG1 . ILE E 2 284 ? 113.050 140.279 146.858 1.00 38.29  ? 230 ILE C CG1 1 
ATOM   12731 C  CG2 . ILE E 2 284 ? 112.152 138.872 148.704 1.00 49.61  ? 230 ILE C CG2 1 
ATOM   12732 C  CD1 . ILE E 2 284 ? 111.657 140.789 146.621 1.00 43.74  ? 230 ILE C CD1 1 
ATOM   12733 N  N   . LEU E 2 285 ? 114.592 136.178 148.296 1.00 33.97  ? 231 LEU C N   1 
ATOM   12734 C  CA  . LEU E 2 285 ? 114.645 134.963 149.105 1.00 36.05  ? 231 LEU C CA  1 
ATOM   12735 C  C   . LEU E 2 285 ? 115.947 134.866 149.891 1.00 38.90  ? 231 LEU C C   1 
ATOM   12736 O  O   . LEU E 2 285 ? 115.946 134.482 151.068 1.00 42.78  ? 231 LEU C O   1 
ATOM   12737 C  CB  . LEU E 2 285 ? 114.471 133.734 148.218 1.00 33.24  ? 231 LEU C CB  1 
ATOM   12738 C  CG  . LEU E 2 285 ? 113.085 133.541 147.615 1.00 40.45  ? 231 LEU C CG  1 
ATOM   12739 C  CD1 . LEU E 2 285 ? 113.032 132.246 146.850 1.00 38.18  ? 231 LEU C CD1 1 
ATOM   12740 C  CD2 . LEU E 2 285 ? 112.038 133.569 148.703 1.00 38.42  ? 231 LEU C CD2 1 
ATOM   12741 N  N   . ILE E 2 286 ? 117.069 135.202 149.254 1.00 35.65  ? 232 ILE C N   1 
ATOM   12742 C  CA  . ILE E 2 286 ? 118.358 135.157 149.937 1.00 33.88  ? 232 ILE C CA  1 
ATOM   12743 C  C   . ILE E 2 286 ? 118.402 136.160 151.079 1.00 38.31  ? 232 ILE C C   1 
ATOM   12744 O  O   . ILE E 2 286 ? 118.922 135.864 152.160 1.00 42.80  ? 232 ILE C O   1 
ATOM   12745 C  CB  . ILE E 2 286 ? 119.496 135.398 148.935 1.00 34.22  ? 232 ILE C CB  1 
ATOM   12746 C  CG1 . ILE E 2 286 ? 119.962 134.083 148.347 1.00 37.63  ? 232 ILE C CG1 1 
ATOM   12747 C  CG2 . ILE E 2 286 ? 120.660 136.084 149.596 1.00 41.78  ? 232 ILE C CG2 1 
ATOM   12748 C  CD1 . ILE E 2 286 ? 120.776 134.286 147.133 1.00 49.89  ? 232 ILE C CD1 1 
ATOM   12749 N  N   . THR E 2 287 ? 117.879 137.367 150.858 1.00 37.40  ? 233 THR C N   1 
ATOM   12750 C  CA  . THR E 2 287 ? 117.889 138.353 151.932 1.00 37.47  ? 233 THR C CA  1 
ATOM   12751 C  C   . THR E 2 287 ? 117.032 137.895 153.105 1.00 41.12  ? 233 THR C C   1 
ATOM   12752 O  O   . THR E 2 287 ? 117.402 138.090 154.270 1.00 47.91  ? 233 THR C O   1 
ATOM   12753 C  CB  . THR E 2 287 ? 117.423 139.705 151.412 1.00 41.75  ? 233 THR C CB  1 
ATOM   12754 O  OG1 . THR E 2 287 ? 118.082 139.983 150.173 1.00 46.39  ? 233 THR C OG1 1 
ATOM   12755 C  CG2 . THR E 2 287 ? 117.782 140.785 152.399 1.00 44.29  ? 233 THR C CG2 1 
ATOM   12756 N  N   . ILE E 2 288 ? 115.891 137.266 152.822 1.00 39.22  ? 234 ILE C N   1 
ATOM   12757 C  CA  . ILE E 2 288 ? 115.053 136.747 153.901 1.00 39.11  ? 234 ILE C CA  1 
ATOM   12758 C  C   . ILE E 2 288 ? 115.792 135.667 154.684 1.00 38.93  ? 234 ILE C C   1 
ATOM   12759 O  O   . ILE E 2 288 ? 115.775 135.647 155.926 1.00 41.67  ? 234 ILE C O   1 
ATOM   12760 C  CB  . ILE E 2 288 ? 113.720 136.232 153.330 1.00 38.68  ? 234 ILE C CB  1 
ATOM   12761 C  CG1 . ILE E 2 288 ? 112.909 137.395 152.759 1.00 35.74  ? 234 ILE C CG1 1 
ATOM   12762 C  CG2 . ILE E 2 288 ? 112.930 135.501 154.390 1.00 39.97  ? 234 ILE C CG2 1 
ATOM   12763 C  CD1 . ILE E 2 288 ? 111.624 136.975 152.117 1.00 34.29  ? 234 ILE C CD1 1 
ATOM   12764 N  N   . LEU E 2 289 ? 116.463 134.757 153.977 1.00 36.47  ? 235 LEU C N   1 
ATOM   12765 C  CA  . LEU E 2 289 ? 117.217 133.717 154.669 1.00 36.08  ? 235 LEU C CA  1 
ATOM   12766 C  C   . LEU E 2 289 ? 118.332 134.316 155.514 1.00 40.30  ? 235 LEU C C   1 
ATOM   12767 O  O   . LEU E 2 289 ? 118.626 133.818 156.605 1.00 46.43  ? 235 LEU C O   1 
ATOM   12768 C  CB  . LEU E 2 289 ? 117.784 132.717 153.669 1.00 34.59  ? 235 LEU C CB  1 
ATOM   12769 C  CG  . LEU E 2 289 ? 118.636 131.595 154.254 1.00 28.23  ? 235 LEU C CG  1 
ATOM   12770 C  CD1 . LEU E 2 289 ? 117.793 130.664 155.093 1.00 32.55  ? 235 LEU C CD1 1 
ATOM   12771 C  CD2 . LEU E 2 289 ? 119.337 130.844 153.156 1.00 21.32  ? 235 LEU C CD2 1 
ATOM   12772 N  N   . SER E 2 290 ? 118.965 135.383 155.029 1.00 37.92  ? 236 SER C N   1 
ATOM   12773 C  CA  . SER E 2 290 ? 119.989 136.046 155.827 1.00 40.67  ? 236 SER C CA  1 
ATOM   12774 C  C   . SER E 2 290 ? 119.394 136.626 157.100 1.00 45.79  ? 236 SER C C   1 
ATOM   12775 O  O   . SER E 2 290 ? 119.998 136.535 158.174 1.00 45.67  ? 236 SER C O   1 
ATOM   12776 C  CB  . SER E 2 290 ? 120.673 137.137 155.011 1.00 38.72  ? 236 SER C CB  1 
ATOM   12777 O  OG  . SER E 2 290 ? 119.922 138.333 155.038 1.00 42.39  ? 236 SER C OG  1 
ATOM   12778 N  N   . TRP E 2 291 ? 118.208 137.230 156.999 1.00 47.75  ? 237 TRP C N   1 
ATOM   12779 C  CA  . TRP E 2 291 ? 117.550 137.760 158.191 1.00 43.90  ? 237 TRP C CA  1 
ATOM   12780 C  C   . TRP E 2 291 ? 117.243 136.672 159.202 1.00 45.59  ? 237 TRP C C   1 
ATOM   12781 O  O   . TRP E 2 291 ? 117.238 136.936 160.408 1.00 48.33  ? 237 TRP C O   1 
ATOM   12782 C  CB  . TRP E 2 291 ? 116.250 138.459 157.831 1.00 38.65  ? 237 TRP C CB  1 
ATOM   12783 C  CG  . TRP E 2 291 ? 116.400 139.580 156.918 1.00 43.21  ? 237 TRP C CG  1 
ATOM   12784 C  CD1 . TRP E 2 291 ? 117.531 140.283 156.653 1.00 42.55  ? 237 TRP C CD1 1 
ATOM   12785 C  CD2 . TRP E 2 291 ? 115.374 140.143 156.113 1.00 47.72  ? 237 TRP C CD2 1 
ATOM   12786 N  NE1 . TRP E 2 291 ? 117.269 141.263 155.733 1.00 45.44  ? 237 TRP C NE1 1 
ATOM   12787 C  CE2 . TRP E 2 291 ? 115.947 141.194 155.384 1.00 49.98  ? 237 TRP C CE2 1 
ATOM   12788 C  CE3 . TRP E 2 291 ? 114.020 139.860 155.937 1.00 44.79  ? 237 TRP C CE3 1 
ATOM   12789 C  CZ2 . TRP E 2 291 ? 115.215 141.962 154.497 1.00 50.40  ? 237 TRP C CZ2 1 
ATOM   12790 C  CZ3 . TRP E 2 291 ? 113.298 140.621 155.056 1.00 46.90  ? 237 TRP C CZ3 1 
ATOM   12791 C  CH2 . TRP E 2 291 ? 113.895 141.660 154.346 1.00 49.78  ? 237 TRP C CH2 1 
ATOM   12792 N  N   . VAL E 2 292 ? 116.948 135.458 158.730 1.00 45.07  ? 238 VAL C N   1 
ATOM   12793 C  CA  . VAL E 2 292 ? 116.562 134.376 159.640 1.00 47.82  ? 238 VAL C CA  1 
ATOM   12794 C  C   . VAL E 2 292 ? 117.554 134.219 160.791 1.00 50.40  ? 238 VAL C C   1 
ATOM   12795 O  O   . VAL E 2 292 ? 117.165 133.865 161.910 1.00 49.18  ? 238 VAL C O   1 
ATOM   12796 C  CB  . VAL E 2 292 ? 116.406 133.056 158.857 1.00 43.45  ? 238 VAL C CB  1 
ATOM   12797 C  CG1 . VAL E 2 292 ? 116.437 131.857 159.788 1.00 37.29  ? 238 VAL C CG1 1 
ATOM   12798 C  CG2 . VAL E 2 292 ? 115.120 133.064 158.075 1.00 48.82  ? 238 VAL C CG2 1 
ATOM   12799 N  N   . SER E 2 293 ? 118.835 134.512 160.555 1.00 51.22  ? 239 SER C N   1 
ATOM   12800 C  CA  . SER E 2 293 ? 119.861 134.200 161.546 1.00 51.62  ? 239 SER C CA  1 
ATOM   12801 C  C   . SER E 2 293 ? 119.731 135.058 162.798 1.00 52.86  ? 239 SER C C   1 
ATOM   12802 O  O   . SER E 2 293 ? 120.265 134.703 163.853 1.00 58.16  ? 239 SER C O   1 
ATOM   12803 C  CB  . SER E 2 293 ? 121.250 134.370 160.938 1.00 48.41  ? 239 SER C CB  1 
ATOM   12804 O  OG  . SER E 2 293 ? 121.622 135.732 160.922 1.00 46.10  ? 239 SER C OG  1 
ATOM   12805 N  N   . PHE E 2 294 ? 119.035 136.191 162.710 1.00 52.72  ? 240 PHE C N   1 
ATOM   12806 C  CA  . PHE E 2 294 ? 118.888 137.048 163.880 1.00 51.96  ? 240 PHE C CA  1 
ATOM   12807 C  C   . PHE E 2 294 ? 118.052 136.408 164.976 1.00 55.80  ? 240 PHE C C   1 
ATOM   12808 O  O   . PHE E 2 294 ? 118.089 136.880 166.115 1.00 61.50  ? 240 PHE C O   1 
ATOM   12809 C  CB  . PHE E 2 294 ? 118.254 138.380 163.493 1.00 52.37  ? 240 PHE C CB  1 
ATOM   12810 C  CG  . PHE E 2 294 ? 119.036 139.148 162.480 1.00 55.23  ? 240 PHE C CG  1 
ATOM   12811 C  CD1 . PHE E 2 294 ? 120.391 139.339 162.631 1.00 56.51  ? 240 PHE C CD1 1 
ATOM   12812 C  CD2 . PHE E 2 294 ? 118.414 139.674 161.369 1.00 53.71  ? 240 PHE C CD2 1 
ATOM   12813 C  CE1 . PHE E 2 294 ? 121.107 140.044 161.694 1.00 54.12  ? 240 PHE C CE1 1 
ATOM   12814 C  CE2 . PHE E 2 294 ? 119.127 140.375 160.433 1.00 53.22  ? 240 PHE C CE2 1 
ATOM   12815 C  CZ  . PHE E 2 294 ? 120.474 140.558 160.595 1.00 53.68  ? 240 PHE C CZ  1 
ATOM   12816 N  N   . TRP E 2 295 ? 117.303 135.358 164.666 1.00 53.25  ? 241 TRP C N   1 
ATOM   12817 C  CA  . TRP E 2 295 ? 116.408 134.721 165.617 1.00 54.88  ? 241 TRP C CA  1 
ATOM   12818 C  C   . TRP E 2 295 ? 117.057 133.554 166.346 1.00 56.94  ? 241 TRP C C   1 
ATOM   12819 O  O   . TRP E 2 295 ? 116.375 132.853 167.098 1.00 60.95  ? 241 TRP C O   1 
ATOM   12820 C  CB  . TRP E 2 295 ? 115.142 134.256 164.902 1.00 51.78  ? 241 TRP C CB  1 
ATOM   12821 C  CG  . TRP E 2 295 ? 114.401 135.373 164.250 1.00 53.57  ? 241 TRP C CG  1 
ATOM   12822 C  CD1 . TRP E 2 295 ? 114.778 136.074 163.144 1.00 54.21  ? 241 TRP C CD1 1 
ATOM   12823 C  CD2 . TRP E 2 295 ? 113.148 135.920 164.662 1.00 53.59  ? 241 TRP C CD2 1 
ATOM   12824 N  NE1 . TRP E 2 295 ? 113.840 137.025 162.843 1.00 54.50  ? 241 TRP C NE1 1 
ATOM   12825 C  CE2 . TRP E 2 295 ? 112.827 136.950 163.760 1.00 53.64  ? 241 TRP C CE2 1 
ATOM   12826 C  CE3 . TRP E 2 295 ? 112.265 135.637 165.705 1.00 50.45  ? 241 TRP C CE3 1 
ATOM   12827 C  CZ2 . TRP E 2 295 ? 111.666 137.696 163.870 1.00 49.91  ? 241 TRP C CZ2 1 
ATOM   12828 C  CZ3 . TRP E 2 295 ? 111.114 136.380 165.811 1.00 51.60  ? 241 TRP C CZ3 1 
ATOM   12829 C  CH2 . TRP E 2 295 ? 110.824 137.398 164.901 1.00 51.38  ? 241 TRP C CH2 1 
ATOM   12830 N  N   . ILE E 2 296 ? 118.348 133.329 166.139 1.00 56.29  ? 242 ILE C N   1 
ATOM   12831 C  CA  . ILE E 2 296 ? 119.079 132.257 166.796 1.00 58.30  ? 242 ILE C CA  1 
ATOM   12832 C  C   . ILE E 2 296 ? 119.992 132.864 167.851 1.00 62.48  ? 242 ILE C C   1 
ATOM   12833 O  O   . ILE E 2 296 ? 120.511 133.972 167.686 1.00 63.19  ? 242 ILE C O   1 
ATOM   12834 C  CB  . ILE E 2 296 ? 119.886 131.427 165.779 1.00 50.75  ? 242 ILE C CB  1 
ATOM   12835 C  CG1 . ILE E 2 296 ? 119.037 131.135 164.546 1.00 44.83  ? 242 ILE C CG1 1 
ATOM   12836 C  CG2 . ILE E 2 296 ? 120.333 130.132 166.396 1.00 51.03  ? 242 ILE C CG2 1 
ATOM   12837 C  CD1 . ILE E 2 296 ? 119.693 130.200 163.569 1.00 43.66  ? 242 ILE C CD1 1 
ATOM   12838 N  N   . ASN E 2 297 ? 120.178 132.135 168.948 1.00 65.43  ? 243 ASN C N   1 
ATOM   12839 C  CA  . ASN E 2 297 ? 121.041 132.609 170.019 1.00 68.60  ? 243 ASN C CA  1 
ATOM   12840 C  C   . ASN E 2 297 ? 122.475 132.745 169.531 1.00 72.09  ? 243 ASN C C   1 
ATOM   12841 O  O   . ASN E 2 297 ? 122.953 131.959 168.711 1.00 72.65  ? 243 ASN C O   1 
ATOM   12842 C  CB  . ASN E 2 297 ? 120.987 131.658 171.211 1.00 73.79  ? 243 ASN C CB  1 
ATOM   12843 C  CG  . ASN E 2 297 ? 119.635 131.648 171.880 1.00 89.60  ? 243 ASN C CG  1 
ATOM   12844 O  OD1 . ASN E 2 297 ? 119.342 132.497 172.722 1.00 88.64  ? 243 ASN C OD1 1 
ATOM   12845 N  ND2 . ASN E 2 297 ? 118.797 130.689 171.507 1.00 92.30  ? 243 ASN C ND2 1 
ATOM   12846 N  N   . TYR E 2 298 ? 123.168 133.759 170.049 1.00 74.03  ? 244 TYR C N   1 
ATOM   12847 C  CA  . TYR E 2 298 ? 124.539 134.008 169.631 1.00 75.44  ? 244 TYR C CA  1 
ATOM   12848 C  C   . TYR E 2 298 ? 125.511 132.952 170.133 1.00 76.61  ? 244 TYR C C   1 
ATOM   12849 O  O   . TYR E 2 298 ? 126.678 132.969 169.729 1.00 75.57  ? 244 TYR C O   1 
ATOM   12850 C  CB  . TYR E 2 298 ? 124.990 135.394 170.082 1.00 77.69  ? 244 TYR C CB  1 
ATOM   12851 C  CG  . TYR E 2 298 ? 124.395 135.856 171.388 1.00 83.42  ? 244 TYR C CG  1 
ATOM   12852 C  CD1 . TYR E 2 298 ? 125.008 135.563 172.596 1.00 88.82  ? 244 TYR C CD1 1 
ATOM   12853 C  CD2 . TYR E 2 298 ? 123.229 136.603 171.412 1.00 85.97  ? 244 TYR C CD2 1 
ATOM   12854 C  CE1 . TYR E 2 298 ? 124.468 135.989 173.788 1.00 93.59  ? 244 TYR C CE1 1 
ATOM   12855 C  CE2 . TYR E 2 298 ? 122.683 137.035 172.601 1.00 95.49  ? 244 TYR C CE2 1 
ATOM   12856 C  CZ  . TYR E 2 298 ? 123.308 136.727 173.787 1.00 97.79  ? 244 TYR C CZ  1 
ATOM   12857 O  OH  . TYR E 2 298 ? 122.766 137.158 174.976 1.00 94.31  ? 244 TYR C OH  1 
ATOM   12858 N  N   . ASP E 2 299 ? 125.070 132.052 171.011 1.00 76.66  ? 245 ASP C N   1 
ATOM   12859 C  CA  . ASP E 2 299 ? 125.896 130.906 171.367 1.00 74.13  ? 245 ASP C CA  1 
ATOM   12860 C  C   . ASP E 2 299 ? 126.138 130.012 170.160 1.00 72.95  ? 245 ASP C C   1 
ATOM   12861 O  O   . ASP E 2 299 ? 127.238 129.478 169.983 1.00 77.11  ? 245 ASP C O   1 
ATOM   12862 C  CB  . ASP E 2 299 ? 125.232 130.116 172.490 1.00 77.61  ? 245 ASP C CB  1 
ATOM   12863 C  CG  . ASP E 2 299 ? 124.850 130.988 173.658 1.00 88.12  ? 245 ASP C CG  1 
ATOM   12864 O  OD1 . ASP E 2 299 ? 125.073 132.214 173.578 1.00 87.55  ? 245 ASP C OD1 1 
ATOM   12865 O  OD2 . ASP E 2 299 ? 124.327 130.451 174.656 1.00 94.91  ? 245 ASP C OD2 1 
ATOM   12866 N  N   . ALA E 2 300 ? 125.119 129.834 169.320 1.00 67.08  ? 246 ALA C N   1 
ATOM   12867 C  CA  . ALA E 2 300 ? 125.227 128.993 168.130 1.00 61.77  ? 246 ALA C CA  1 
ATOM   12868 C  C   . ALA E 2 300 ? 126.060 129.736 167.092 1.00 63.29  ? 246 ALA C C   1 
ATOM   12869 O  O   . ALA E 2 300 ? 125.552 130.329 166.140 1.00 62.68  ? 246 ALA C O   1 
ATOM   12870 C  CB  . ALA E 2 300 ? 123.847 128.643 167.592 1.00 54.64  ? 246 ALA C CB  1 
ATOM   12871 N  N   . SER E 2 301 ? 127.377 129.704 167.292 1.00 62.92  ? 247 SER C N   1 
ATOM   12872 C  CA  . SER E 2 301 ? 128.279 130.415 166.394 1.00 53.69  ? 247 SER C CA  1 
ATOM   12873 C  C   . SER E 2 301 ? 128.380 129.727 165.039 1.00 52.77  ? 247 SER C C   1 
ATOM   12874 O  O   . SER E 2 301 ? 128.362 130.391 163.998 1.00 53.04  ? 247 SER C O   1 
ATOM   12875 C  CB  . SER E 2 301 ? 129.657 130.538 167.036 1.00 56.23  ? 247 SER C CB  1 
ATOM   12876 O  OG  . SER E 2 301 ? 130.555 131.215 166.178 1.00 65.36  ? 247 SER C OG  1 
ATOM   12877 N  N   . ALA E 2 302 ? 128.501 128.399 165.032 1.00 54.26  ? 248 ALA C N   1 
ATOM   12878 C  CA  . ALA E 2 302 ? 128.681 127.681 163.776 1.00 52.04  ? 248 ALA C CA  1 
ATOM   12879 C  C   . ALA E 2 302 ? 127.475 127.847 162.863 1.00 50.71  ? 248 ALA C C   1 
ATOM   12880 O  O   . ALA E 2 302 ? 127.626 128.090 161.660 1.00 51.15  ? 248 ALA C O   1 
ATOM   12881 C  CB  . ALA E 2 302 ? 128.946 126.205 164.054 1.00 47.51  ? 248 ALA C CB  1 
ATOM   12882 N  N   . ALA E 2 303 ? 126.269 127.743 163.423 1.00 49.61  ? 249 ALA C N   1 
ATOM   12883 C  CA  . ALA E 2 303 ? 125.060 127.885 162.622 1.00 49.87  ? 249 ALA C CA  1 
ATOM   12884 C  C   . ALA E 2 303 ? 124.977 129.265 161.981 1.00 50.75  ? 249 ALA C C   1 
ATOM   12885 O  O   . ALA E 2 303 ? 124.730 129.389 160.775 1.00 50.91  ? 249 ALA C O   1 
ATOM   12886 C  CB  . ALA E 2 303 ? 123.833 127.624 163.492 1.00 41.31  ? 249 ALA C CB  1 
ATOM   12887 N  N   . ARG E 2 304 ? 125.194 130.318 162.773 1.00 48.93  ? 250 ARG C N   1 
ATOM   12888 C  CA  . ARG E 2 304 ? 125.047 131.675 162.260 1.00 46.59  ? 250 ARG C CA  1 
ATOM   12889 C  C   . ARG E 2 304 ? 126.139 132.014 161.258 1.00 47.05  ? 250 ARG C C   1 
ATOM   12890 O  O   . ARG E 2 304 ? 125.876 132.672 160.244 1.00 49.79  ? 250 ARG C O   1 
ATOM   12891 C  CB  . ARG E 2 304 ? 125.041 132.672 163.413 1.00 47.93  ? 250 ARG C CB  1 
ATOM   12892 C  CG  . ARG E 2 304 ? 123.910 132.442 164.385 1.00 52.04  ? 250 ARG C CG  1 
ATOM   12893 C  CD  . ARG E 2 304 ? 123.814 133.537 165.418 1.00 55.43  ? 250 ARG C CD  1 
ATOM   12894 N  NE  . ARG E 2 304 ? 123.536 134.832 164.816 1.00 56.96  ? 250 ARG C NE  1 
ATOM   12895 C  CZ  . ARG E 2 304 ? 123.060 135.876 165.477 1.00 59.50  ? 250 ARG C CZ  1 
ATOM   12896 N  NH1 . ARG E 2 304 ? 122.777 135.806 166.766 1.00 63.51  ? 250 ARG C NH1 1 
ATOM   12897 N  NH2 . ARG E 2 304 ? 122.858 137.017 164.829 1.00 58.50  ? 250 ARG C NH2 1 
ATOM   12898 N  N   . VAL E 2 305 ? 127.369 131.573 161.520 1.00 44.88  ? 251 VAL C N   1 
ATOM   12899 C  CA  . VAL E 2 305 ? 128.453 131.816 160.576 1.00 43.11  ? 251 VAL C CA  1 
ATOM   12900 C  C   . VAL E 2 305 ? 128.175 131.113 159.256 1.00 44.86  ? 251 VAL C C   1 
ATOM   12901 O  O   . VAL E 2 305 ? 128.361 131.690 158.176 1.00 48.93  ? 251 VAL C O   1 
ATOM   12902 C  CB  . VAL E 2 305 ? 129.797 131.384 161.185 1.00 41.51  ? 251 VAL C CB  1 
ATOM   12903 C  CG1 . VAL E 2 305 ? 130.865 131.325 160.120 1.00 45.44  ? 251 VAL C CG1 1 
ATOM   12904 C  CG2 . VAL E 2 305 ? 130.202 132.347 162.279 1.00 41.67  ? 251 VAL C CG2 1 
ATOM   12905 N  N   . ALA E 2 306 ? 127.712 129.862 159.316 1.00 43.91  ? 252 ALA C N   1 
ATOM   12906 C  CA  . ALA E 2 306 ? 127.383 129.142 158.094 1.00 41.71  ? 252 ALA C CA  1 
ATOM   12907 C  C   . ALA E 2 306 ? 126.269 129.837 157.324 1.00 45.33  ? 252 ALA C C   1 
ATOM   12908 O  O   . ALA E 2 306 ? 126.344 129.966 156.097 1.00 46.83  ? 252 ALA C O   1 
ATOM   12909 C  CB  . ALA E 2 306 ? 126.990 127.706 158.428 1.00 39.06  ? 252 ALA C CB  1 
ATOM   12910 N  N   . LEU E 2 307 ? 125.225 130.290 158.024 1.00 44.74  ? 253 LEU C N   1 
ATOM   12911 C  CA  . LEU E 2 307 ? 124.124 130.976 157.353 1.00 43.86  ? 253 LEU C CA  1 
ATOM   12912 C  C   . LEU E 2 307 ? 124.605 132.242 156.660 1.00 43.66  ? 253 LEU C C   1 
ATOM   12913 O  O   . LEU E 2 307 ? 124.274 132.493 155.493 1.00 48.60  ? 253 LEU C O   1 
ATOM   12914 C  CB  . LEU E 2 307 ? 123.021 131.308 158.354 1.00 41.55  ? 253 LEU C CB  1 
ATOM   12915 C  CG  . LEU E 2 307 ? 122.021 130.201 158.667 1.00 41.25  ? 253 LEU C CG  1 
ATOM   12916 C  CD1 . LEU E 2 307 ? 121.125 130.622 159.799 1.00 42.46  ? 253 LEU C CD1 1 
ATOM   12917 C  CD2 . LEU E 2 307 ? 121.198 129.892 157.444 1.00 34.83  ? 253 LEU C CD2 1 
ATOM   12918 N  N   . GLY E 2 308 ? 125.391 133.053 157.367 1.00 37.08  ? 254 GLY C N   1 
ATOM   12919 C  CA  . GLY E 2 308 ? 125.883 134.283 156.771 1.00 39.91  ? 254 GLY C CA  1 
ATOM   12920 C  C   . GLY E 2 308 ? 126.748 134.032 155.554 1.00 44.46  ? 254 GLY C C   1 
ATOM   12921 O  O   . GLY E 2 308 ? 126.599 134.693 154.520 1.00 48.90  ? 254 GLY C O   1 
ATOM   12922 N  N   . ILE E 2 309 ? 127.659 133.064 155.655 1.00 42.37  ? 255 ILE C N   1 
ATOM   12923 C  CA  . ILE E 2 309 ? 128.563 132.778 154.547 1.00 42.04  ? 255 ILE C CA  1 
ATOM   12924 C  C   . ILE E 2 309 ? 127.790 132.253 153.345 1.00 44.62  ? 255 ILE C C   1 
ATOM   12925 O  O   . ILE E 2 309 ? 128.050 132.646 152.201 1.00 48.71  ? 255 ILE C O   1 
ATOM   12926 C  CB  . ILE E 2 309 ? 129.659 131.799 154.993 1.00 43.72  ? 255 ILE C CB  1 
ATOM   12927 C  CG1 . ILE E 2 309 ? 130.603 132.499 155.968 1.00 45.11  ? 255 ILE C CG1 1 
ATOM   12928 C  CG2 . ILE E 2 309 ? 130.415 131.262 153.799 1.00 43.42  ? 255 ILE C CG2 1 
ATOM   12929 C  CD1 . ILE E 2 309 ? 131.840 131.722 156.273 1.00 46.46  ? 255 ILE C CD1 1 
ATOM   12930 N  N   . THR E 2 310 ? 126.834 131.354 153.584 1.00 43.30  ? 256 THR C N   1 
ATOM   12931 C  CA  . THR E 2 310 ? 126.038 130.815 152.489 1.00 43.25  ? 256 THR C CA  1 
ATOM   12932 C  C   . THR E 2 310 ? 125.264 131.914 151.778 1.00 45.27  ? 256 THR C C   1 
ATOM   12933 O  O   . THR E 2 310 ? 125.235 131.962 150.541 1.00 49.42  ? 256 THR C O   1 
ATOM   12934 C  CB  . THR E 2 310 ? 125.082 129.752 153.018 1.00 46.21  ? 256 THR C CB  1 
ATOM   12935 O  OG1 . THR E 2 310 ? 125.832 128.698 153.632 1.00 56.97  ? 256 THR C OG1 1 
ATOM   12936 C  CG2 . THR E 2 310 ? 124.242 129.183 151.897 1.00 44.70  ? 256 THR C CG2 1 
ATOM   12937 N  N   . THR E 2 311 ? 124.632 132.811 152.539 1.00 40.46  ? 257 THR C N   1 
ATOM   12938 C  CA  . THR E 2 311 ? 123.879 133.888 151.908 1.00 37.74  ? 257 THR C CA  1 
ATOM   12939 C  C   . THR E 2 311 ? 124.787 134.799 151.096 1.00 43.95  ? 257 THR C C   1 
ATOM   12940 O  O   . THR E 2 311 ? 124.436 135.190 149.975 1.00 51.70  ? 257 THR C O   1 
ATOM   12941 C  CB  . THR E 2 311 ? 123.116 134.686 152.957 1.00 39.45  ? 257 THR C CB  1 
ATOM   12942 O  OG1 . THR E 2 311 ? 124.006 135.064 154.012 1.00 47.88  ? 257 THR C OG1 1 
ATOM   12943 C  CG2 . THR E 2 311 ? 121.987 133.859 153.526 1.00 38.52  ? 257 THR C CG2 1 
ATOM   12944 N  N   . VAL E 2 312 ? 125.963 135.138 151.632 1.00 44.56  ? 258 VAL C N   1 
ATOM   12945 C  CA  . VAL E 2 312 ? 126.883 136.005 150.900 1.00 42.08  ? 258 VAL C CA  1 
ATOM   12946 C  C   . VAL E 2 312 ? 127.304 135.354 149.588 1.00 42.80  ? 258 VAL C C   1 
ATOM   12947 O  O   . VAL E 2 312 ? 127.273 135.983 148.523 1.00 48.70  ? 258 VAL C O   1 
ATOM   12948 C  CB  . VAL E 2 312 ? 128.103 136.353 151.770 1.00 37.66  ? 258 VAL C CB  1 
ATOM   12949 C  CG1 . VAL E 2 312 ? 129.159 137.025 150.939 1.00 40.08  ? 258 VAL C CG1 1 
ATOM   12950 C  CG2 . VAL E 2 312 ? 127.704 137.255 152.907 1.00 40.38  ? 258 VAL C CG2 1 
ATOM   12951 N  N   . LEU E 2 313 ? 127.691 134.080 149.641 1.00 42.62  ? 259 LEU C N   1 
ATOM   12952 C  CA  . LEU E 2 313 ? 128.170 133.415 148.434 1.00 46.72  ? 259 LEU C CA  1 
ATOM   12953 C  C   . LEU E 2 313 ? 127.067 133.285 147.390 1.00 48.02  ? 259 LEU C C   1 
ATOM   12954 O  O   . LEU E 2 313 ? 127.305 133.495 146.193 1.00 52.94  ? 259 LEU C O   1 
ATOM   12955 C  CB  . LEU E 2 313 ? 128.754 132.052 148.790 1.00 49.44  ? 259 LEU C CB  1 
ATOM   12956 C  CG  . LEU E 2 313 ? 130.008 132.132 149.658 1.00 45.40  ? 259 LEU C CG  1 
ATOM   12957 C  CD1 . LEU E 2 313 ? 130.496 130.750 150.017 1.00 44.18  ? 259 LEU C CD1 1 
ATOM   12958 C  CD2 . LEU E 2 313 ? 131.092 132.911 148.946 1.00 41.54  ? 259 LEU C CD2 1 
ATOM   12959 N  N   . THR E 2 314 ? 125.848 132.954 147.818 1.00 41.61  ? 260 THR C N   1 
ATOM   12960 C  CA  . THR E 2 314 ? 124.766 132.816 146.852 1.00 40.75  ? 260 THR C CA  1 
ATOM   12961 C  C   . THR E 2 314 ? 124.384 134.158 146.231 1.00 45.27  ? 260 THR C C   1 
ATOM   12962 O  O   . THR E 2 314 ? 124.077 134.224 145.032 1.00 49.08  ? 260 THR C O   1 
ATOM   12963 C  CB  . THR E 2 314 ? 123.564 132.156 147.516 1.00 41.31  ? 260 THR C CB  1 
ATOM   12964 O  OG1 . THR E 2 314 ? 124.023 131.201 148.476 1.00 43.25  ? 260 THR C OG1 1 
ATOM   12965 C  CG2 . THR E 2 314 ? 122.735 131.426 146.487 1.00 47.35  ? 260 THR C CG2 1 
ATOM   12966 N  N   . MET E 2 315 ? 124.410 135.239 147.014 1.00 44.74  ? 261 MET C N   1 
ATOM   12967 C  CA  . MET E 2 315 ? 124.156 136.556 146.439 1.00 45.50  ? 261 MET C CA  1 
ATOM   12968 C  C   . MET E 2 315 ? 125.237 136.938 145.432 1.00 49.53  ? 261 MET C C   1 
ATOM   12969 O  O   . MET E 2 315 ? 124.943 137.549 144.395 1.00 52.07  ? 261 MET C O   1 
ATOM   12970 C  CB  . MET E 2 315 ? 124.049 137.596 147.551 1.00 42.17  ? 261 MET C CB  1 
ATOM   12971 C  CG  . MET E 2 315 ? 123.842 139.007 147.065 1.00 51.64  ? 261 MET C CG  1 
ATOM   12972 S  SD  . MET E 2 315 ? 122.408 139.183 145.996 1.00 59.57  ? 261 MET C SD  1 
ATOM   12973 C  CE  . MET E 2 315 ? 121.106 138.822 147.151 1.00 48.94  ? 261 MET C CE  1 
ATOM   12974 N  N   . THR E 2 316 ? 126.493 136.589 145.718 1.00 48.52  ? 262 THR C N   1 
ATOM   12975 C  CA  . THR E 2 316 ? 127.558 136.822 144.746 1.00 47.08  ? 262 THR C CA  1 
ATOM   12976 C  C   . THR E 2 316 ? 127.301 136.056 143.454 1.00 49.83  ? 262 THR C C   1 
ATOM   12977 O  O   . THR E 2 316 ? 127.524 136.577 142.352 1.00 52.24  ? 262 THR C O   1 
ATOM   12978 C  CB  . THR E 2 316 ? 128.906 136.432 145.344 1.00 46.89  ? 262 THR C CB  1 
ATOM   12979 O  OG1 . THR E 2 316 ? 129.289 137.403 146.322 1.00 49.71  ? 262 THR C OG1 1 
ATOM   12980 C  CG2 . THR E 2 316 ? 129.965 136.375 144.275 1.00 56.02  ? 262 THR C CG2 1 
ATOM   12981 N  N   . THR E 2 317 ? 126.828 134.814 143.572 1.00 50.47  ? 263 THR C N   1 
ATOM   12982 C  CA  . THR E 2 317 ? 126.478 134.040 142.384 1.00 49.41  ? 263 THR C CA  1 
ATOM   12983 C  C   . THR E 2 317 ? 125.402 134.740 141.565 1.00 50.19  ? 263 THR C C   1 
ATOM   12984 O  O   . THR E 2 317 ? 125.496 134.813 140.334 1.00 57.78  ? 263 THR C O   1 
ATOM   12985 C  CB  . THR E 2 317 ? 126.005 132.645 142.783 1.00 48.22  ? 263 THR C CB  1 
ATOM   12986 O  OG1 . THR E 2 317 ? 127.125 131.853 143.191 1.00 60.36  ? 263 THR C OG1 1 
ATOM   12987 C  CG2 . THR E 2 317 ? 125.316 131.967 141.625 1.00 41.44  ? 263 THR C CG2 1 
ATOM   12988 N  N   . ILE E 2 318 ? 124.373 135.263 142.231 1.00 46.47  ? 264 ILE C N   1 
ATOM   12989 C  CA  . ILE E 2 318 ? 123.310 135.956 141.504 1.00 48.13  ? 264 ILE C CA  1 
ATOM   12990 C  C   . ILE E 2 318 ? 123.857 137.180 140.778 1.00 49.90  ? 264 ILE C C   1 
ATOM   12991 O  O   . ILE E 2 318 ? 123.518 137.432 139.611 1.00 55.53  ? 264 ILE C O   1 
ATOM   12992 C  CB  . ILE E 2 318 ? 122.166 136.334 142.457 1.00 52.61  ? 264 ILE C CB  1 
ATOM   12993 C  CG1 . ILE E 2 318 ? 121.512 135.074 143.010 1.00 48.68  ? 264 ILE C CG1 1 
ATOM   12994 C  CG2 . ILE E 2 318 ? 121.143 137.191 141.741 1.00 45.45  ? 264 ILE C CG2 1 
ATOM   12995 C  CD1 . ILE E 2 318 ? 120.304 135.346 143.832 1.00 37.11  ? 264 ILE C CD1 1 
ATOM   12996 N  N   . ASN E 2 319 ? 124.703 137.963 141.454 1.00 50.56  ? 265 ASN C N   1 
ATOM   12997 C  CA  . ASN E 2 319 ? 125.280 139.145 140.816 1.00 49.04  ? 265 ASN C CA  1 
ATOM   12998 C  C   . ASN E 2 319 ? 126.066 138.766 139.568 1.00 55.43  ? 265 ASN C C   1 
ATOM   12999 O  O   . ASN E 2 319 ? 125.904 139.382 138.507 1.00 58.99  ? 265 ASN C O   1 
ATOM   13000 C  CB  . ASN E 2 319 ? 126.184 139.895 141.793 1.00 47.20  ? 265 ASN C CB  1 
ATOM   13001 C  CG  . ASN E 2 319 ? 125.434 140.437 142.987 1.00 60.57  ? 265 ASN C CG  1 
ATOM   13002 O  OD1 . ASN E 2 319 ? 124.304 140.037 143.255 1.00 65.96  ? 265 ASN C OD1 1 
ATOM   13003 N  ND2 . ASN E 2 319 ? 126.064 141.349 143.719 1.00 53.88  ? 265 ASN C ND2 1 
ATOM   13004 N  N   . THR E 2 320 ? 126.925 137.748 139.674 1.00 56.54  ? 266 THR C N   1 
ATOM   13005 C  CA  . THR E 2 320 ? 127.742 137.373 138.523 1.00 54.24  ? 266 THR C CA  1 
ATOM   13006 C  C   . THR E 2 320 ? 126.884 136.849 137.382 1.00 56.79  ? 266 THR C C   1 
ATOM   13007 O  O   . THR E 2 320 ? 127.150 137.146 136.212 1.00 63.72  ? 266 THR C O   1 
ATOM   13008 C  CB  . THR E 2 320 ? 128.788 136.335 138.909 1.00 53.82  ? 266 THR C CB  1 
ATOM   13009 O  OG1 . THR E 2 320 ? 128.138 135.122 139.296 1.00 58.21  ? 266 THR C OG1 1 
ATOM   13010 C  CG2 . THR E 2 320 ? 129.646 136.848 140.047 1.00 53.65  ? 266 THR C CG2 1 
ATOM   13011 N  N   . HIS E 2 321 ? 125.858 136.059 137.696 1.00 55.56  ? 267 HIS C N   1 
ATOM   13012 C  CA  . HIS E 2 321 ? 124.996 135.531 136.645 1.00 58.03  ? 267 HIS C CA  1 
ATOM   13013 C  C   . HIS E 2 321 ? 124.306 136.656 135.885 1.00 59.94  ? 267 HIS C C   1 
ATOM   13014 O  O   . HIS E 2 321 ? 124.305 136.679 134.644 1.00 64.01  ? 267 HIS C O   1 
ATOM   13015 C  CB  . HIS E 2 321 ? 123.973 134.575 137.249 1.00 57.60  ? 267 HIS C CB  1 
ATOM   13016 C  CG  . HIS E 2 321 ? 122.810 134.296 136.354 1.00 74.79  ? 267 HIS C CG  1 
ATOM   13017 N  ND1 . HIS E 2 321 ? 121.642 135.026 136.403 1.00 81.28  ? 267 HIS C ND1 1 
ATOM   13018 C  CD2 . HIS E 2 321 ? 122.633 133.371 135.383 1.00 81.23  ? 267 HIS C CD2 1 
ATOM   13019 C  CE1 . HIS E 2 321 ? 120.795 134.560 135.504 1.00 81.26  ? 267 HIS C CE1 1 
ATOM   13020 N  NE2 . HIS E 2 321 ? 121.372 133.556 134.870 1.00 89.27  ? 267 HIS C NE2 1 
ATOM   13021 N  N   . LEU E 2 322 ? 123.731 137.618 136.610 1.00 59.07  ? 268 LEU C N   1 
ATOM   13022 C  CA  . LEU E 2 322 ? 123.078 138.720 135.912 1.00 57.31  ? 268 LEU C CA  1 
ATOM   13023 C  C   . LEU E 2 322 ? 124.077 139.512 135.085 1.00 57.51  ? 268 LEU C C   1 
ATOM   13024 O  O   . LEU E 2 322 ? 123.798 139.860 133.933 1.00 58.27  ? 268 LEU C O   1 
ATOM   13025 C  CB  . LEU E 2 322 ? 122.359 139.647 136.884 1.00 58.76  ? 268 LEU C CB  1 
ATOM   13026 C  CG  . LEU E 2 322 ? 121.660 140.757 136.099 1.00 56.07  ? 268 LEU C CG  1 
ATOM   13027 C  CD1 . LEU E 2 322 ? 120.698 140.149 135.100 1.00 56.74  ? 268 LEU C CD1 1 
ATOM   13028 C  CD2 . LEU E 2 322 ? 120.934 141.724 136.993 1.00 56.56  ? 268 LEU C CD2 1 
ATOM   13029 N  N   . ARG E 2 323 ? 125.256 139.795 135.642 1.00 58.35  ? 269 ARG C N   1 
ATOM   13030 C  CA  . ARG E 2 323 ? 126.237 140.556 134.879 1.00 57.83  ? 269 ARG C CA  1 
ATOM   13031 C  C   . ARG E 2 323 ? 126.662 139.810 133.622 1.00 60.88  ? 269 ARG C C   1 
ATOM   13032 O  O   . ARG E 2 323 ? 126.973 140.438 132.605 1.00 62.58  ? 269 ARG C O   1 
ATOM   13033 C  CB  . ARG E 2 323 ? 127.451 140.881 135.746 1.00 61.86  ? 269 ARG C CB  1 
ATOM   13034 C  CG  . ARG E 2 323 ? 128.485 141.733 135.038 1.00 73.14  ? 269 ARG C CG  1 
ATOM   13035 C  CD  . ARG E 2 323 ? 129.623 142.135 135.952 1.00 79.00  ? 269 ARG C CD  1 
ATOM   13036 N  NE  . ARG E 2 323 ? 130.508 143.100 135.311 1.00 88.29  ? 269 ARG C NE  1 
ATOM   13037 C  CZ  . ARG E 2 323 ? 131.583 142.779 134.605 1.00 89.53  ? 269 ARG C CZ  1 
ATOM   13038 N  NH1 . ARG E 2 323 ? 131.943 141.519 134.429 1.00 91.27  ? 269 ARG C NH1 1 
ATOM   13039 N  NH2 . ARG E 2 323 ? 132.315 143.747 134.060 1.00 82.39  ? 269 ARG C NH2 1 
ATOM   13040 N  N   . GLU E 2 324 ? 126.673 138.477 133.663 1.00 63.07  ? 270 GLU C N   1 
ATOM   13041 C  CA  . GLU E 2 324 ? 127.038 137.721 132.470 1.00 61.12  ? 270 GLU C CA  1 
ATOM   13042 C  C   . GLU E 2 324 ? 125.928 137.725 131.429 1.00 57.89  ? 270 GLU C C   1 
ATOM   13043 O  O   . GLU E 2 324 ? 126.214 137.632 130.231 1.00 57.35  ? 270 GLU C O   1 
ATOM   13044 C  CB  . GLU E 2 324 ? 127.408 136.287 132.837 1.00 59.00  ? 270 GLU C CB  1 
ATOM   13045 C  CG  . GLU E 2 324 ? 128.731 136.173 133.563 1.00 70.43  ? 270 GLU C CG  1 
ATOM   13046 C  CD  . GLU E 2 324 ? 129.297 134.772 133.525 1.00 90.12  ? 270 GLU C CD  1 
ATOM   13047 O  OE1 . GLU E 2 324 ? 128.610 133.868 133.009 1.00 95.21  ? 270 GLU C OE1 1 
ATOM   13048 O  OE2 . GLU E 2 324 ? 130.433 134.576 134.007 1.00 98.26  ? 270 GLU C OE2 1 
ATOM   13049 N  N   . THR E 2 325 ? 124.665 137.825 131.850 1.00 61.53  ? 271 THR C N   1 
ATOM   13050 C  CA  . THR E 2 325 ? 123.592 137.875 130.858 1.00 58.36  ? 271 THR C CA  1 
ATOM   13051 C  C   . THR E 2 325 ? 123.533 139.191 130.086 1.00 56.48  ? 271 THR C C   1 
ATOM   13052 O  O   . THR E 2 325 ? 122.772 139.282 129.118 1.00 53.27  ? 271 THR C O   1 
ATOM   13053 C  CB  . THR E 2 325 ? 122.237 137.627 131.514 1.00 58.11  ? 271 THR C CB  1 
ATOM   13054 O  OG1 . THR E 2 325 ? 122.038 138.571 132.570 1.00 64.49  ? 271 THR C OG1 1 
ATOM   13055 C  CG2 . THR E 2 325 ? 122.171 136.219 132.071 1.00 58.12  ? 271 THR C CG2 1 
ATOM   13056 N  N   . LEU E 2 326 ? 124.300 140.201 130.477 1.00 57.56  ? 272 LEU C N   1 
ATOM   13057 C  CA  . LEU E 2 326 ? 124.319 141.503 129.832 1.00 53.24  ? 272 LEU C CA  1 
ATOM   13058 C  C   . LEU E 2 326 ? 125.732 141.843 129.373 1.00 56.45  ? 272 LEU C C   1 
ATOM   13059 O  O   . LEU E 2 326 ? 126.712 141.318 129.913 1.00 59.73  ? 272 LEU C O   1 
ATOM   13060 C  CB  . LEU E 2 326 ? 123.815 142.595 130.787 1.00 51.37  ? 272 LEU C CB  1 
ATOM   13061 C  CG  . LEU E 2 326 ? 122.382 142.536 131.313 1.00 52.98  ? 272 LEU C CG  1 
ATOM   13062 C  CD1 . LEU E 2 326 ? 122.058 143.805 132.064 1.00 51.51  ? 272 LEU C CD1 1 
ATOM   13063 C  CD2 . LEU E 2 326 ? 121.395 142.328 130.189 1.00 51.73  ? 272 LEU C CD2 1 
ATOM   13064 N  N   . PRO E 2 327 ? 125.877 142.708 128.371 1.00 57.05  ? 273 PRO C N   1 
ATOM   13065 C  CA  . PRO E 2 327 ? 127.218 143.077 127.907 1.00 56.63  ? 273 PRO C CA  1 
ATOM   13066 C  C   . PRO E 2 327 ? 127.983 143.871 128.953 1.00 63.00  ? 273 PRO C C   1 
ATOM   13067 O  O   . PRO E 2 327 ? 127.403 144.569 129.786 1.00 61.78  ? 273 PRO C O   1 
ATOM   13068 C  CB  . PRO E 2 327 ? 126.938 143.925 126.665 1.00 52.44  ? 273 PRO C CB  1 
ATOM   13069 C  CG  . PRO E 2 327 ? 125.588 144.479 126.898 1.00 49.80  ? 273 PRO C CG  1 
ATOM   13070 C  CD  . PRO E 2 327 ? 124.830 143.400 127.605 1.00 54.45  ? 273 PRO C CD  1 
ATOM   13071 N  N   . LYS E 2 328 ? 129.308 143.763 128.893 1.00 63.37  ? 274 LYS C N   1 
ATOM   13072 C  CA  . LYS E 2 328 ? 130.176 144.424 129.859 1.00 63.59  ? 274 LYS C CA  1 
ATOM   13073 C  C   . LYS E 2 328 ? 130.431 145.859 129.424 1.00 61.56  ? 274 LYS C C   1 
ATOM   13074 O  O   . LYS E 2 328 ? 131.002 146.096 128.357 1.00 65.64  ? 274 LYS C O   1 
ATOM   13075 C  CB  . LYS E 2 328 ? 131.496 143.671 130.004 1.00 66.28  ? 274 LYS C CB  1 
ATOM   13076 C  CG  . LYS E 2 328 ? 131.432 142.454 130.908 1.00 71.62  ? 274 LYS C CG  1 
ATOM   13077 C  CD  . LYS E 2 328 ? 130.851 141.254 130.188 1.00 74.41  ? 274 LYS C CD  1 
ATOM   13078 C  CE  . LYS E 2 328 ? 130.700 140.074 131.123 1.00 72.31  ? 274 LYS C CE  1 
ATOM   13079 N  NZ  . LYS E 2 328 ? 130.250 138.868 130.384 1.00 71.50  ? 274 LYS C NZ  1 
ATOM   13080 N  N   . ILE E 2 329 ? 130.029 146.811 130.259 1.00 63.87  ? 275 ILE C N   1 
ATOM   13081 C  CA  . ILE E 2 329 ? 130.230 148.230 129.979 1.00 68.16  ? 275 ILE C CA  1 
ATOM   13082 C  C   . ILE E 2 329 ? 130.898 148.863 131.192 1.00 75.80  ? 275 ILE C C   1 
ATOM   13083 O  O   . ILE E 2 329 ? 130.768 148.364 132.321 1.00 74.80  ? 275 ILE C O   1 
ATOM   13084 C  CB  . ILE E 2 329 ? 128.901 148.937 129.625 1.00 67.96  ? 275 ILE C CB  1 
ATOM   13085 C  CG1 . ILE E 2 329 ? 127.790 148.533 130.589 1.00 71.32  ? 275 ILE C CG1 1 
ATOM   13086 C  CG2 . ILE E 2 329 ? 128.496 148.620 128.201 1.00 65.33  ? 275 ILE C CG2 1 
ATOM   13087 C  CD1 . ILE E 2 329 ? 127.626 149.461 131.750 1.00 72.71  ? 275 ILE C CD1 1 
ATOM   13088 N  N   . PRO E 2 330 ? 131.640 149.958 130.991 1.00 80.64  ? 276 PRO C N   1 
ATOM   13089 C  CA  . PRO E 2 330 ? 132.411 150.516 132.115 1.00 80.59  ? 276 PRO C CA  1 
ATOM   13090 C  C   . PRO E 2 330 ? 131.561 151.128 133.215 1.00 84.02  ? 276 PRO C C   1 
ATOM   13091 O  O   . PRO E 2 330 ? 131.909 150.998 134.394 1.00 84.31  ? 276 PRO C O   1 
ATOM   13092 C  CB  . PRO E 2 330 ? 133.297 151.566 131.433 1.00 77.48  ? 276 PRO C CB  1 
ATOM   13093 C  CG  . PRO E 2 330 ? 132.540 151.959 130.224 1.00 75.53  ? 276 PRO C CG  1 
ATOM   13094 C  CD  . PRO E 2 330 ? 131.882 150.701 129.743 1.00 77.34  ? 276 PRO C CD  1 
ATOM   13095 N  N   . TYR E 2 331 ? 130.459 151.791 132.877 1.00 81.37  ? 277 TYR C N   1 
ATOM   13096 C  CA  . TYR E 2 331 ? 129.707 152.531 133.879 1.00 78.82  ? 277 TYR C CA  1 
ATOM   13097 C  C   . TYR E 2 331 ? 128.820 151.595 134.699 1.00 78.61  ? 277 TYR C C   1 
ATOM   13098 O  O   . TYR E 2 331 ? 128.812 150.376 134.515 1.00 80.00  ? 277 TYR C O   1 
ATOM   13099 C  CB  . TYR E 2 331 ? 128.890 153.639 133.217 1.00 81.71  ? 277 TYR C CB  1 
ATOM   13100 C  CG  . TYR E 2 331 ? 127.844 153.153 132.243 1.00 90.11  ? 277 TYR C CG  1 
ATOM   13101 C  CD1 . TYR E 2 331 ? 128.155 152.946 130.906 1.00 93.28  ? 277 TYR C CD1 1 
ATOM   13102 C  CD2 . TYR E 2 331 ? 126.539 152.920 132.656 1.00 86.16  ? 277 TYR C CD2 1 
ATOM   13103 C  CE1 . TYR E 2 331 ? 127.197 152.508 130.012 1.00 94.60  ? 277 TYR C CE1 1 
ATOM   13104 C  CE2 . TYR E 2 331 ? 125.577 152.483 131.771 1.00 87.29  ? 277 TYR C CE2 1 
ATOM   13105 C  CZ  . TYR E 2 331 ? 125.910 152.277 130.451 1.00 93.34  ? 277 TYR C CZ  1 
ATOM   13106 O  OH  . TYR E 2 331 ? 124.954 151.839 129.567 1.00 86.76  ? 277 TYR C OH  1 
ATOM   13107 N  N   . VAL E 2 332 ? 128.067 152.177 135.629 1.00 76.13  ? 278 VAL C N   1 
ATOM   13108 C  CA  . VAL E 2 332 ? 127.221 151.438 136.558 1.00 69.01  ? 278 VAL C CA  1 
ATOM   13109 C  C   . VAL E 2 332 ? 125.774 151.838 136.315 1.00 69.91  ? 278 VAL C C   1 
ATOM   13110 O  O   . VAL E 2 332 ? 125.451 153.030 136.292 1.00 71.64  ? 278 VAL C O   1 
ATOM   13111 C  CB  . VAL E 2 332 ? 127.624 151.702 138.021 1.00 60.70  ? 278 VAL C CB  1 
ATOM   13112 C  CG1 . VAL E 2 332 ? 126.523 151.275 138.961 1.00 60.17  ? 278 VAL C CG1 1 
ATOM   13113 C  CG2 . VAL E 2 332 ? 128.905 150.969 138.358 1.00 64.24  ? 278 VAL C CG2 1 
ATOM   13114 N  N   . LYS E 2 333 ? 124.907 150.843 136.139 1.00 63.52  ? 279 LYS C N   1 
ATOM   13115 C  CA  . LYS E 2 333 ? 123.496 151.065 135.878 1.00 54.34  ? 279 LYS C CA  1 
ATOM   13116 C  C   . LYS E 2 333 ? 122.701 151.014 137.182 1.00 52.31  ? 279 LYS C C   1 
ATOM   13117 O  O   . LYS E 2 333 ? 123.243 150.772 138.260 1.00 57.92  ? 279 LYS C O   1 
ATOM   13118 C  CB  . LYS E 2 333 ? 122.985 150.034 134.873 1.00 53.41  ? 279 LYS C CB  1 
ATOM   13119 C  CG  . LYS E 2 333 ? 123.940 149.792 133.716 1.00 58.81  ? 279 LYS C CG  1 
ATOM   13120 C  CD  . LYS E 2 333 ? 123.260 149.087 132.553 1.00 55.32  ? 279 LYS C CD  1 
ATOM   13121 C  CE  . LYS E 2 333 ? 123.082 147.606 132.803 1.00 53.37  ? 279 LYS C CE  1 
ATOM   13122 N  NZ  . LYS E 2 333 ? 124.366 146.875 132.669 1.00 56.89  ? 279 LYS C NZ  1 
ATOM   13123 N  N   . ALA E 2 334 ? 121.393 151.248 137.087 1.00 51.28  ? 280 ALA C N   1 
ATOM   13124 C  CA  . ALA E 2 334 ? 120.541 151.168 138.269 1.00 50.68  ? 280 ALA C CA  1 
ATOM   13125 C  C   . ALA E 2 334 ? 120.462 149.745 138.809 1.00 53.63  ? 280 ALA C C   1 
ATOM   13126 O  O   . ALA E 2 334 ? 120.460 149.535 140.029 1.00 57.73  ? 280 ALA C O   1 
ATOM   13127 C  CB  . ALA E 2 334 ? 119.144 151.690 137.942 1.00 53.70  ? 280 ALA C CB  1 
ATOM   13128 N  N   . ILE E 2 335 ? 120.384 148.756 137.918 1.00 50.29  ? 281 ILE C N   1 
ATOM   13129 C  CA  . ILE E 2 335 ? 120.256 147.370 138.355 1.00 47.18  ? 281 ILE C CA  1 
ATOM   13130 C  C   . ILE E 2 335 ? 121.522 146.912 139.071 1.00 53.32  ? 281 ILE C C   1 
ATOM   13131 O  O   . ILE E 2 335 ? 121.464 146.136 140.035 1.00 55.39  ? 281 ILE C O   1 
ATOM   13132 C  CB  . ILE E 2 335 ? 119.904 146.472 137.157 1.00 44.50  ? 281 ILE C CB  1 
ATOM   13133 C  CG1 . ILE E 2 335 ? 119.638 145.048 137.625 1.00 45.85  ? 281 ILE C CG1 1 
ATOM   13134 C  CG2 . ILE E 2 335 ? 120.987 146.520 136.097 1.00 44.74  ? 281 ILE C CG2 1 
ATOM   13135 C  CD1 . ILE E 2 335 ? 118.530 144.959 138.619 1.00 40.93  ? 281 ILE C CD1 1 
ATOM   13136 N  N   . ASP E 2 336 ? 122.683 147.389 138.625 1.00 52.01  ? 282 ASP C N   1 
ATOM   13137 C  CA  . ASP E 2 336 ? 123.917 147.098 139.343 1.00 48.64  ? 282 ASP C CA  1 
ATOM   13138 C  C   . ASP E 2 336 ? 123.873 147.677 140.746 1.00 52.99  ? 282 ASP C C   1 
ATOM   13139 O  O   . ASP E 2 336 ? 124.339 147.049 141.700 1.00 59.80  ? 282 ASP C O   1 
ATOM   13140 C  CB  . ASP E 2 336 ? 125.114 147.647 138.575 1.00 49.66  ? 282 ASP C CB  1 
ATOM   13141 C  CG  . ASP E 2 336 ? 125.365 146.909 137.287 1.00 61.70  ? 282 ASP C CG  1 
ATOM   13142 O  OD1 . ASP E 2 336 ? 125.133 145.684 137.246 1.00 67.12  ? 282 ASP C OD1 1 
ATOM   13143 O  OD2 . ASP E 2 336 ? 125.802 147.551 136.313 1.00 68.46  ? 282 ASP C OD2 1 
ATOM   13144 N  N   . MET E 2 337 ? 123.309 148.877 140.890 1.00 51.30  ? 283 MET C N   1 
ATOM   13145 C  CA  . MET E 2 337 ? 123.154 149.471 142.211 1.00 49.91  ? 283 MET C CA  1 
ATOM   13146 C  C   . MET E 2 337 ? 122.240 148.632 143.092 1.00 49.83  ? 283 MET C C   1 
ATOM   13147 O  O   . MET E 2 337 ? 122.512 148.455 144.282 1.00 54.44  ? 283 MET C O   1 
ATOM   13148 C  CB  . MET E 2 337 ? 122.619 150.893 142.088 1.00 53.38  ? 283 MET C CB  1 
ATOM   13149 C  CG  . MET E 2 337 ? 123.624 151.893 141.568 1.00 64.96  ? 283 MET C CG  1 
ATOM   13150 S  SD  . MET E 2 337 ? 125.058 152.021 142.643 1.00 93.46  ? 283 MET C SD  1 
ATOM   13151 C  CE  . MET E 2 337 ? 125.755 153.568 142.078 1.00 83.10  ? 283 MET C CE  1 
ATOM   13152 N  N   . TYR E 2 338 ? 121.150 148.105 142.530 1.00 46.90  ? 284 TYR C N   1 
ATOM   13153 C  CA  . TYR E 2 338 ? 120.258 147.260 143.321 1.00 44.16  ? 284 TYR C CA  1 
ATOM   13154 C  C   . TYR E 2 338 ? 120.952 145.984 143.783 1.00 45.60  ? 284 TYR C C   1 
ATOM   13155 O  O   . TYR E 2 338 ? 120.815 145.574 144.943 1.00 54.35  ? 284 TYR C O   1 
ATOM   13156 C  CB  . TYR E 2 338 ? 119.008 146.912 142.522 1.00 43.35  ? 284 TYR C CB  1 
ATOM   13157 C  CG  . TYR E 2 338 ? 118.164 145.844 143.166 1.00 46.41  ? 284 TYR C CG  1 
ATOM   13158 C  CD1 . TYR E 2 338 ? 117.319 146.145 144.220 1.00 48.28  ? 284 TYR C CD1 1 
ATOM   13159 C  CD2 . TYR E 2 338 ? 118.209 144.534 142.720 1.00 47.64  ? 284 TYR C CD2 1 
ATOM   13160 C  CE1 . TYR E 2 338 ? 116.550 145.177 144.812 1.00 46.36  ? 284 TYR C CE1 1 
ATOM   13161 C  CE2 . TYR E 2 338 ? 117.445 143.560 143.309 1.00 45.79  ? 284 TYR C CE2 1 
ATOM   13162 C  CZ  . TYR E 2 338 ? 116.616 143.889 144.352 1.00 48.55  ? 284 TYR C CZ  1 
ATOM   13163 O  OH  . TYR E 2 338 ? 115.849 142.918 144.944 1.00 56.84  ? 284 TYR C OH  1 
ATOM   13164 N  N   . LEU E 2 339 ? 121.680 145.324 142.886 1.00 43.61  ? 285 LEU C N   1 
ATOM   13165 C  CA  . LEU E 2 339 ? 122.367 144.100 143.289 1.00 44.14  ? 285 LEU C CA  1 
ATOM   13166 C  C   . LEU E 2 339 ? 123.456 144.386 144.316 1.00 44.71  ? 285 LEU C C   1 
ATOM   13167 O  O   . LEU E 2 339 ? 123.650 143.607 145.257 1.00 47.91  ? 285 LEU C O   1 
ATOM   13168 C  CB  . LEU E 2 339 ? 122.937 143.390 142.069 1.00 49.28  ? 285 LEU C CB  1 
ATOM   13169 C  CG  . LEU E 2 339 ? 121.888 142.666 141.231 1.00 47.57  ? 285 LEU C CG  1 
ATOM   13170 C  CD1 . LEU E 2 339 ? 122.562 141.929 140.108 1.00 52.35  ? 285 LEU C CD1 1 
ATOM   13171 C  CD2 . LEU E 2 339 ? 121.095 141.711 142.090 1.00 48.49  ? 285 LEU C CD2 1 
ATOM   13172 N  N   . MET E 2 340 ? 124.169 145.502 144.161 1.00 44.24  ? 286 MET C N   1 
ATOM   13173 C  CA  . MET E 2 340 ? 125.146 145.891 145.170 1.00 43.83  ? 286 MET C CA  1 
ATOM   13174 C  C   . MET E 2 340 ? 124.471 146.168 146.505 1.00 45.48  ? 286 MET C C   1 
ATOM   13175 O  O   . MET E 2 340 ? 125.025 145.857 147.562 1.00 49.55  ? 286 MET C O   1 
ATOM   13176 C  CB  . MET E 2 340 ? 125.935 147.112 144.702 1.00 50.63  ? 286 MET C CB  1 
ATOM   13177 C  CG  . MET E 2 340 ? 126.958 147.600 145.711 1.00 70.78  ? 286 MET C CG  1 
ATOM   13178 S  SD  . MET E 2 340 ? 127.866 149.069 145.191 1.00 121.48 ? 286 MET C SD  1 
ATOM   13179 C  CE  . MET E 2 340 ? 128.909 149.347 146.624 1.00 86.26  ? 286 MET C CE  1 
ATOM   13180 N  N   . GLY E 2 341 ? 123.275 146.753 146.479 1.00 44.26  ? 287 GLY C N   1 
ATOM   13181 C  CA  . GLY E 2 341 ? 122.544 146.970 147.716 1.00 42.88  ? 287 GLY C CA  1 
ATOM   13182 C  C   . GLY E 2 341 ? 122.163 145.676 148.409 1.00 45.88  ? 287 GLY C C   1 
ATOM   13183 O  O   . GLY E 2 341 ? 122.284 145.555 149.629 1.00 49.16  ? 287 GLY C O   1 
ATOM   13184 N  N   . CYS E 2 342 ? 121.697 144.691 147.642 1.00 42.05  ? 288 CYS C N   1 
ATOM   13185 C  CA  . CYS E 2 342 ? 121.381 143.395 148.236 1.00 39.58  ? 288 CYS C CA  1 
ATOM   13186 C  C   . CYS E 2 342 ? 122.624 142.742 148.835 1.00 45.43  ? 288 CYS C C   1 
ATOM   13187 O  O   . CYS E 2 342 ? 122.572 142.163 149.933 1.00 52.80  ? 288 CYS C O   1 
ATOM   13188 C  CB  . CYS E 2 342 ? 120.741 142.481 147.194 1.00 43.15  ? 288 CYS C CB  1 
ATOM   13189 S  SG  . CYS E 2 342 ? 119.074 142.938 146.696 1.00 54.07  ? 288 CYS C SG  1 
ATOM   13190 N  N   . PHE E 2 343 ? 123.755 142.828 148.130 1.00 42.73  ? 289 PHE C N   1 
ATOM   13191 C  CA  . PHE E 2 343 ? 124.999 142.302 148.681 1.00 39.98  ? 289 PHE C CA  1 
ATOM   13192 C  C   . PHE E 2 343 ? 125.380 143.022 149.967 1.00 46.11  ? 289 PHE C C   1 
ATOM   13193 O  O   . PHE E 2 343 ? 125.836 142.393 150.930 1.00 52.72  ? 289 PHE C O   1 
ATOM   13194 C  CB  . PHE E 2 343 ? 126.126 142.417 147.658 1.00 40.31  ? 289 PHE C CB  1 
ATOM   13195 C  CG  . PHE E 2 343 ? 127.419 141.823 148.125 1.00 46.91  ? 289 PHE C CG  1 
ATOM   13196 C  CD1 . PHE E 2 343 ? 127.698 140.490 147.910 1.00 49.65  ? 289 PHE C CD1 1 
ATOM   13197 C  CD2 . PHE E 2 343 ? 128.352 142.594 148.791 1.00 46.36  ? 289 PHE C CD2 1 
ATOM   13198 C  CE1 . PHE E 2 343 ? 128.882 139.940 148.345 1.00 48.04  ? 289 PHE C CE1 1 
ATOM   13199 C  CE2 . PHE E 2 343 ? 129.534 142.047 149.229 1.00 49.14  ? 289 PHE C CE2 1 
ATOM   13200 C  CZ  . PHE E 2 343 ? 129.799 140.718 149.004 1.00 49.81  ? 289 PHE C CZ  1 
ATOM   13201 N  N   . VAL E 2 344 ? 125.218 144.345 149.993 1.00 42.94  ? 290 VAL C N   1 
ATOM   13202 C  CA  . VAL E 2 344 ? 125.518 145.113 151.195 1.00 40.38  ? 290 VAL C CA  1 
ATOM   13203 C  C   . VAL E 2 344 ? 124.644 144.655 152.347 1.00 44.43  ? 290 VAL C C   1 
ATOM   13204 O  O   . VAL E 2 344 ? 125.106 144.544 153.484 1.00 51.02  ? 290 VAL C O   1 
ATOM   13205 C  CB  . VAL E 2 344 ? 125.354 146.619 150.922 1.00 37.73  ? 290 VAL C CB  1 
ATOM   13206 C  CG1 . VAL E 2 344 ? 125.236 147.389 152.220 1.00 34.49  ? 290 VAL C CG1 1 
ATOM   13207 C  CG2 . VAL E 2 344 ? 126.526 147.125 150.122 1.00 43.24  ? 290 VAL C CG2 1 
ATOM   13208 N  N   . PHE E 2 345 ? 123.374 144.367 152.074 1.00 41.96  ? 291 PHE C N   1 
ATOM   13209 C  CA  . PHE E 2 345 ? 122.479 143.938 153.145 1.00 41.87  ? 291 PHE C CA  1 
ATOM   13210 C  C   . PHE E 2 345 ? 122.891 142.589 153.727 1.00 42.95  ? 291 PHE C C   1 
ATOM   13211 O  O   . PHE E 2 345 ? 122.935 142.424 154.953 1.00 50.04  ? 291 PHE C O   1 
ATOM   13212 C  CB  . PHE E 2 345 ? 121.040 143.899 152.644 1.00 41.28  ? 291 PHE C CB  1 
ATOM   13213 C  CG  . PHE E 2 345 ? 120.313 145.192 152.828 1.00 43.43  ? 291 PHE C CG  1 
ATOM   13214 C  CD1 . PHE E 2 345 ? 119.688 145.479 154.021 1.00 45.28  ? 291 PHE C CD1 1 
ATOM   13215 C  CD2 . PHE E 2 345 ? 120.272 146.129 151.819 1.00 45.22  ? 291 PHE C CD2 1 
ATOM   13216 C  CE1 . PHE E 2 345 ? 119.031 146.669 154.197 1.00 49.93  ? 291 PHE C CE1 1 
ATOM   13217 C  CE2 . PHE E 2 345 ? 119.611 147.320 151.991 1.00 46.89  ? 291 PHE C CE2 1 
ATOM   13218 C  CZ  . PHE E 2 345 ? 118.992 147.590 153.181 1.00 50.89  ? 291 PHE C CZ  1 
ATOM   13219 N  N   . VAL E 2 346 ? 123.214 141.613 152.873 1.00 40.00  ? 292 VAL C N   1 
ATOM   13220 C  CA  . VAL E 2 346 ? 123.607 140.319 153.440 1.00 44.11  ? 292 VAL C CA  1 
ATOM   13221 C  C   . VAL E 2 346 ? 124.945 140.427 154.176 1.00 47.73  ? 292 VAL C C   1 
ATOM   13222 O  O   . VAL E 2 346 ? 125.120 139.850 155.268 1.00 50.28  ? 292 VAL C O   1 
ATOM   13223 C  CB  . VAL E 2 346 ? 123.631 139.208 152.371 1.00 41.79  ? 292 VAL C CB  1 
ATOM   13224 C  CG1 . VAL E 2 346 ? 122.242 138.965 151.830 1.00 42.14  ? 292 VAL C CG1 1 
ATOM   13225 C  CG2 . VAL E 2 346 ? 124.574 139.541 151.247 1.00 45.34  ? 292 VAL C CG2 1 
ATOM   13226 N  N   . PHE E 2 347 ? 125.900 141.177 153.621 1.00 47.18  ? 293 PHE C N   1 
ATOM   13227 C  CA  . PHE E 2 347 ? 127.172 141.328 154.309 1.00 47.57  ? 293 PHE C CA  1 
ATOM   13228 C  C   . PHE E 2 347 ? 127.011 142.080 155.620 1.00 49.70  ? 293 PHE C C   1 
ATOM   13229 O  O   . PHE E 2 347 ? 127.709 141.778 156.591 1.00 55.27  ? 293 PHE C O   1 
ATOM   13230 C  CB  . PHE E 2 347 ? 128.184 142.029 153.412 1.00 45.58  ? 293 PHE C CB  1 
ATOM   13231 C  CG  . PHE E 2 347 ? 129.584 141.919 153.909 1.00 54.32  ? 293 PHE C CG  1 
ATOM   13232 C  CD1 . PHE E 2 347 ? 130.275 140.730 153.794 1.00 52.38  ? 293 PHE C CD1 1 
ATOM   13233 C  CD2 . PHE E 2 347 ? 130.202 142.991 154.518 1.00 54.10  ? 293 PHE C CD2 1 
ATOM   13234 C  CE1 . PHE E 2 347 ? 131.561 140.617 154.267 1.00 51.43  ? 293 PHE C CE1 1 
ATOM   13235 C  CE2 . PHE E 2 347 ? 131.486 142.884 154.990 1.00 54.23  ? 293 PHE C CE2 1 
ATOM   13236 C  CZ  . PHE E 2 347 ? 132.167 141.697 154.865 1.00 55.44  ? 293 PHE C CZ  1 
ATOM   13237 N  N   . LEU E 2 348 ? 126.095 143.047 155.675 1.00 46.65  ? 294 LEU C N   1 
ATOM   13238 C  CA  . LEU E 2 348 ? 125.845 143.767 156.913 1.00 45.91  ? 294 LEU C CA  1 
ATOM   13239 C  C   . LEU E 2 348 ? 125.205 142.876 157.959 1.00 51.36  ? 294 LEU C C   1 
ATOM   13240 O  O   . LEU E 2 348 ? 125.469 143.047 159.149 1.00 54.57  ? 294 LEU C O   1 
ATOM   13241 C  CB  . LEU E 2 348 ? 124.958 144.979 156.653 1.00 43.93  ? 294 LEU C CB  1 
ATOM   13242 C  CG  . LEU E 2 348 ? 125.672 146.266 156.265 1.00 43.16  ? 294 LEU C CG  1 
ATOM   13243 C  CD1 . LEU E 2 348 ? 124.675 147.394 156.171 1.00 44.58  ? 294 LEU C CD1 1 
ATOM   13244 C  CD2 . LEU E 2 348 ? 126.736 146.576 157.286 1.00 42.58  ? 294 LEU C CD2 1 
ATOM   13245 N  N   . ALA E 2 349 ? 124.350 141.939 157.550 1.00 51.12  ? 295 ALA C N   1 
ATOM   13246 C  CA  . ALA E 2 349 ? 123.822 140.986 158.522 1.00 49.36  ? 295 ALA C CA  1 
ATOM   13247 C  C   . ALA E 2 349 ? 124.938 140.139 159.127 1.00 52.10  ? 295 ALA C C   1 
ATOM   13248 O  O   . ALA E 2 349 ? 125.014 139.972 160.357 1.00 58.04  ? 295 ALA C O   1 
ATOM   13249 C  CB  . ALA E 2 349 ? 122.766 140.101 157.867 1.00 42.53  ? 295 ALA C CB  1 
ATOM   13250 N  N   . LEU E 2 350 ? 125.835 139.624 158.283 1.00 46.76  ? 296 LEU C N   1 
ATOM   13251 C  CA  . LEU E 2 350 ? 126.953 138.842 158.811 1.00 45.01  ? 296 LEU C CA  1 
ATOM   13252 C  C   . LEU E 2 350 ? 127.843 139.688 159.723 1.00 52.45  ? 296 LEU C C   1 
ATOM   13253 O  O   . LEU E 2 350 ? 128.268 139.237 160.799 1.00 55.48  ? 296 LEU C O   1 
ATOM   13254 C  CB  . LEU E 2 350 ? 127.758 138.247 157.656 1.00 47.52  ? 296 LEU C CB  1 
ATOM   13255 C  CG  . LEU E 2 350 ? 128.947 137.341 157.967 1.00 44.94  ? 296 LEU C CG  1 
ATOM   13256 C  CD1 . LEU E 2 350 ? 128.505 136.119 158.732 1.00 40.66  ? 296 LEU C CD1 1 
ATOM   13257 C  CD2 . LEU E 2 350 ? 129.648 136.939 156.690 1.00 43.09  ? 296 LEU C CD2 1 
ATOM   13258 N  N   . LEU E 2 351 ? 128.119 140.928 159.320 1.00 54.52  ? 297 LEU C N   1 
ATOM   13259 C  CA  . LEU E 2 351 ? 128.953 141.812 160.125 1.00 50.17  ? 297 LEU C CA  1 
ATOM   13260 C  C   . LEU E 2 351 ? 128.285 142.178 161.442 1.00 52.92  ? 297 LEU C C   1 
ATOM   13261 O  O   . LEU E 2 351 ? 128.969 142.348 162.454 1.00 59.51  ? 297 LEU C O   1 
ATOM   13262 C  CB  . LEU E 2 351 ? 129.280 143.074 159.335 1.00 51.04  ? 297 LEU C CB  1 
ATOM   13263 C  CG  . LEU E 2 351 ? 130.739 143.511 159.354 1.00 54.42  ? 297 LEU C CG  1 
ATOM   13264 C  CD1 . LEU E 2 351 ? 131.599 142.469 158.682 1.00 55.84  ? 297 LEU C CD1 1 
ATOM   13265 C  CD2 . LEU E 2 351 ? 130.885 144.844 158.665 1.00 54.49  ? 297 LEU C CD2 1 
ATOM   13266 N  N   . GLU E 2 352 ? 126.961 142.329 161.447 1.00 54.94  ? 298 GLU C N   1 
ATOM   13267 C  CA  . GLU E 2 352 ? 126.256 142.585 162.694 1.00 58.18  ? 298 GLU C CA  1 
ATOM   13268 C  C   . GLU E 2 352 ? 126.390 141.405 163.635 1.00 62.34  ? 298 GLU C C   1 
ATOM   13269 O  O   . GLU E 2 352 ? 126.517 141.582 164.852 1.00 71.84  ? 298 GLU C O   1 
ATOM   13270 C  CB  . GLU E 2 352 ? 124.784 142.892 162.422 1.00 59.46  ? 298 GLU C CB  1 
ATOM   13271 C  CG  . GLU E 2 352 ? 123.939 143.086 163.676 1.00 65.21  ? 298 GLU C CG  1 
ATOM   13272 C  CD  . GLU E 2 352 ? 123.313 141.794 164.172 1.00 69.14  ? 298 GLU C CD  1 
ATOM   13273 O  OE1 . GLU E 2 352 ? 123.548 140.742 163.547 1.00 67.17  ? 298 GLU C OE1 1 
ATOM   13274 O  OE2 . GLU E 2 352 ? 122.583 141.827 165.181 1.00 72.69  ? 298 GLU C OE2 1 
ATOM   13275 N  N   . TYR E 2 353 ? 126.343 140.185 163.098 1.00 59.96  ? 299 TYR C N   1 
ATOM   13276 C  CA  . TYR E 2 353 ? 126.609 139.047 163.972 1.00 60.24  ? 299 TYR C CA  1 
ATOM   13277 C  C   . TYR E 2 353 ? 128.014 139.120 164.553 1.00 60.90  ? 299 TYR C C   1 
ATOM   13278 O  O   . TYR E 2 353 ? 128.217 138.841 165.739 1.00 67.12  ? 299 TYR C O   1 
ATOM   13279 C  CB  . TYR E 2 353 ? 126.426 137.720 163.250 1.00 58.16  ? 299 TYR C CB  1 
ATOM   13280 C  CG  . TYR E 2 353 ? 126.874 136.592 164.137 1.00 57.52  ? 299 TYR C CG  1 
ATOM   13281 C  CD1 . TYR E 2 353 ? 126.338 136.443 165.406 1.00 61.31  ? 299 TYR C CD1 1 
ATOM   13282 C  CD2 . TYR E 2 353 ? 127.851 135.704 163.735 1.00 57.22  ? 299 TYR C CD2 1 
ATOM   13283 C  CE1 . TYR E 2 353 ? 126.745 135.436 166.239 1.00 59.66  ? 299 TYR C CE1 1 
ATOM   13284 C  CE2 . TYR E 2 353 ? 128.265 134.688 164.566 1.00 58.51  ? 299 TYR C CE2 1 
ATOM   13285 C  CZ  . TYR E 2 353 ? 127.707 134.563 165.817 1.00 60.82  ? 299 TYR C CZ  1 
ATOM   13286 O  OH  . TYR E 2 353 ? 128.102 133.561 166.666 1.00 62.55  ? 299 TYR C OH  1 
ATOM   13287 N  N   . ALA E 2 354 ? 129.000 139.487 163.732 1.00 60.89  ? 300 ALA C N   1 
ATOM   13288 C  CA  . ALA E 2 354 ? 130.364 139.605 164.250 1.00 60.68  ? 300 ALA C CA  1 
ATOM   13289 C  C   . ALA E 2 354 ? 130.447 140.646 165.362 1.00 66.76  ? 300 ALA C C   1 
ATOM   13290 O  O   . ALA E 2 354 ? 131.124 140.437 166.376 1.00 72.12  ? 300 ALA C O   1 
ATOM   13291 C  CB  . ALA E 2 354 ? 131.333 139.954 163.123 1.00 54.89  ? 300 ALA C CB  1 
ATOM   13292 N  N   . PHE E 2 355 ? 129.768 141.777 165.182 1.00 70.40  ? 301 PHE C N   1 
ATOM   13293 C  CA  . PHE E 2 355 ? 129.776 142.833 166.191 1.00 72.77  ? 301 PHE C CA  1 
ATOM   13294 C  C   . PHE E 2 355 ? 129.105 142.380 167.484 1.00 78.85  ? 301 PHE C C   1 
ATOM   13295 O  O   . PHE E 2 355 ? 129.602 142.661 168.583 1.00 85.60  ? 301 PHE C O   1 
ATOM   13296 C  CB  . PHE E 2 355 ? 129.093 144.076 165.623 1.00 72.12  ? 301 PHE C CB  1 
ATOM   13297 C  CG  . PHE E 2 355 ? 128.831 145.143 166.635 1.00 80.12  ? 301 PHE C CG  1 
ATOM   13298 C  CD1 . PHE E 2 355 ? 129.874 145.781 167.275 1.00 82.05  ? 301 PHE C CD1 1 
ATOM   13299 C  CD2 . PHE E 2 355 ? 127.537 145.527 166.930 1.00 79.93  ? 301 PHE C CD2 1 
ATOM   13300 C  CE1 . PHE E 2 355 ? 129.629 146.770 168.204 1.00 87.37  ? 301 PHE C CE1 1 
ATOM   13301 C  CE2 . PHE E 2 355 ? 127.288 146.515 167.857 1.00 80.06  ? 301 PHE C CE2 1 
ATOM   13302 C  CZ  . PHE E 2 355 ? 128.334 147.137 168.494 1.00 84.71  ? 301 PHE C CZ  1 
ATOM   13303 N  N   . VAL E 2 356 ? 127.978 141.673 167.375 1.00 77.68  ? 302 VAL C N   1 
ATOM   13304 C  CA  . VAL E 2 356 ? 127.312 141.134 168.559 1.00 77.01  ? 302 VAL C CA  1 
ATOM   13305 C  C   . VAL E 2 356 ? 128.228 140.164 169.287 1.00 79.58  ? 302 VAL C C   1 
ATOM   13306 O  O   . VAL E 2 356 ? 128.341 140.193 170.516 1.00 86.56  ? 302 VAL C O   1 
ATOM   13307 C  CB  . VAL E 2 356 ? 125.984 140.462 168.168 1.00 76.92  ? 302 VAL C CB  1 
ATOM   13308 C  CG1 . VAL E 2 356 ? 125.469 139.597 169.298 1.00 79.41  ? 302 VAL C CG1 1 
ATOM   13309 C  CG2 . VAL E 2 356 ? 124.959 141.506 167.798 1.00 78.56  ? 302 VAL C CG2 1 
ATOM   13310 N  N   . ASN E 2 357 ? 128.902 139.295 168.537 1.00 81.59  ? 303 ASN C N   1 
ATOM   13311 C  CA  . ASN E 2 357 ? 129.809 138.333 169.149 1.00 84.29  ? 303 ASN C CA  1 
ATOM   13312 C  C   . ASN E 2 357 ? 130.963 139.031 169.857 1.00 90.32  ? 303 ASN C C   1 
ATOM   13313 O  O   . ASN E 2 357 ? 131.397 138.595 170.928 1.00 96.42  ? 303 ASN C O   1 
ATOM   13314 C  CB  . ASN E 2 357 ? 130.326 137.370 168.088 1.00 76.36  ? 303 ASN C CB  1 
ATOM   13315 C  CG  . ASN E 2 357 ? 131.333 136.403 168.630 1.00 82.97  ? 303 ASN C CG  1 
ATOM   13316 O  OD1 . ASN E 2 357 ? 131.195 135.908 169.744 1.00 91.66  ? 303 ASN C OD1 1 
ATOM   13317 N  ND2 . ASN E 2 357 ? 132.368 136.130 167.847 1.00 86.84  ? 303 ASN C ND2 1 
ATOM   13318 N  N   . TYR E 2 358 ? 131.486 140.108 169.267 1.00 91.82  ? 304 TYR C N   1 
ATOM   13319 C  CA  . TYR E 2 358 ? 132.553 140.855 169.928 1.00 97.26  ? 304 TYR C CA  1 
ATOM   13320 C  C   . TYR E 2 358 ? 132.065 141.498 171.220 1.00 98.77  ? 304 TYR C C   1 
ATOM   13321 O  O   . TYR E 2 358 ? 132.751 141.440 172.247 1.00 103.87 ? 304 TYR C O   1 
ATOM   13322 C  CB  . TYR E 2 358 ? 133.118 141.923 168.993 1.00 100.06 ? 304 TYR C CB  1 
ATOM   13323 C  CG  . TYR E 2 358 ? 134.378 141.519 168.259 1.00 112.11 ? 304 TYR C CG  1 
ATOM   13324 C  CD1 . TYR E 2 358 ? 135.168 140.473 168.713 1.00 110.99 ? 304 TYR C CD1 1 
ATOM   13325 C  CD2 . TYR E 2 358 ? 134.778 142.193 167.112 1.00 116.68 ? 304 TYR C CD2 1 
ATOM   13326 C  CE1 . TYR E 2 358 ? 136.322 140.109 168.042 1.00 116.20 ? 304 TYR C CE1 1 
ATOM   13327 C  CE2 . TYR E 2 358 ? 135.926 141.837 166.436 1.00 120.57 ? 304 TYR C CE2 1 
ATOM   13328 C  CZ  . TYR E 2 358 ? 136.696 140.796 166.903 1.00 121.22 ? 304 TYR C CZ  1 
ATOM   13329 O  OH  . TYR E 2 358 ? 137.840 140.444 166.225 1.00 118.60 ? 304 TYR C OH  1 
ATOM   13330 N  N   . ILE E 2 359 ? 130.876 142.110 171.195 1.00 98.99  ? 305 ILE C N   1 
ATOM   13331 C  CA  . ILE E 2 359 ? 130.381 142.830 172.369 1.00 99.02  ? 305 ILE C CA  1 
ATOM   13332 C  C   . ILE E 2 359 ? 129.710 141.921 173.385 1.00 100.15 ? 305 ILE C C   1 
ATOM   13333 O  O   . ILE E 2 359 ? 129.336 142.388 174.467 1.00 102.60 ? 305 ILE C O   1 
ATOM   13334 C  CB  . ILE E 2 359 ? 129.398 143.940 171.943 1.00 98.61  ? 305 ILE C CB  1 
ATOM   13335 C  CG1 . ILE E 2 359 ? 129.359 145.055 172.987 1.00 101.32 ? 305 ILE C CG1 1 
ATOM   13336 C  CG2 . ILE E 2 359 ? 128.008 143.370 171.723 1.00 93.74  ? 305 ILE C CG2 1 
ATOM   13337 C  CD1 . ILE E 2 359 ? 128.312 146.103 172.720 1.00 102.17 ? 305 ILE C CD1 1 
ATOM   13338 N  N   . PHE E 2 360 ? 129.553 140.633 173.077 1.00 100.97 ? 306 PHE C N   1 
ATOM   13339 C  CA  . PHE E 2 360 ? 128.837 139.735 173.978 1.00 103.92 ? 306 PHE C CA  1 
ATOM   13340 C  C   . PHE E 2 360 ? 129.581 139.528 175.289 1.00 108.72 ? 306 PHE C C   1 
ATOM   13341 O  O   . PHE E 2 360 ? 128.947 139.389 176.340 1.00 111.01 ? 306 PHE C O   1 
ATOM   13342 C  CB  . PHE E 2 360 ? 128.588 138.394 173.287 1.00 106.09 ? 306 PHE C CB  1 
ATOM   13343 C  CG  . PHE E 2 360 ? 128.352 137.253 174.235 1.00 115.25 ? 306 PHE C CG  1 
ATOM   13344 C  CD1 . PHE E 2 360 ? 127.251 137.244 175.077 1.00 114.28 ? 306 PHE C CD1 1 
ATOM   13345 C  CD2 . PHE E 2 360 ? 129.227 136.178 174.274 1.00 114.80 ? 306 PHE C CD2 1 
ATOM   13346 C  CE1 . PHE E 2 360 ? 127.036 136.194 175.950 1.00 112.46 ? 306 PHE C CE1 1 
ATOM   13347 C  CE2 . PHE E 2 360 ? 129.015 135.124 175.141 1.00 113.27 ? 306 PHE C CE2 1 
ATOM   13348 C  CZ  . PHE E 2 360 ? 127.917 135.132 175.979 1.00 113.96 ? 306 PHE C CZ  1 
ATOM   13349 N  N   . PHE E 2 361 ? 130.914 139.508 175.251 1.00 111.58 ? 307 PHE C N   1 
ATOM   13350 C  CA  . PHE E 2 361 ? 131.683 139.220 176.458 1.00 117.72 ? 307 PHE C CA  1 
ATOM   13351 C  C   . PHE E 2 361 ? 131.427 140.243 177.556 1.00 116.39 ? 307 PHE C C   1 
ATOM   13352 O  O   . PHE E 2 361 ? 131.523 139.914 178.744 1.00 111.95 ? 307 PHE C O   1 
ATOM   13353 C  CB  . PHE E 2 361 ? 133.173 139.162 176.127 1.00 116.99 ? 307 PHE C CB  1 
ATOM   13354 C  CG  . PHE E 2 361 ? 133.551 138.009 175.245 1.00 124.15 ? 307 PHE C CG  1 
ATOM   13355 C  CD1 . PHE E 2 361 ? 133.531 138.136 173.868 1.00 119.99 ? 307 PHE C CD1 1 
ATOM   13356 C  CD2 . PHE E 2 361 ? 133.926 136.794 175.795 1.00 128.45 ? 307 PHE C CD2 1 
ATOM   13357 C  CE1 . PHE E 2 361 ? 133.878 137.078 173.057 1.00 121.84 ? 307 PHE C CE1 1 
ATOM   13358 C  CE2 . PHE E 2 361 ? 134.274 135.731 174.988 1.00 130.05 ? 307 PHE C CE2 1 
ATOM   13359 C  CZ  . PHE E 2 361 ? 134.249 135.875 173.615 1.00 126.55 ? 307 PHE C CZ  1 
ATOM   13360 N  N   . SER E 2 362 ? 131.092 141.477 177.187 1.00 116.52 ? 308 SER C N   1 
ATOM   13361 C  CA  . SER E 2 362 ? 130.921 142.543 178.168 1.00 114.25 ? 308 SER C CA  1 
ATOM   13362 C  C   . SER E 2 362 ? 129.471 142.671 178.627 1.00 113.97 ? 308 SER C C   1 
ATOM   13363 O  O   . SER E 2 362 ? 129.177 142.541 179.819 1.00 111.47 ? 308 SER C O   1 
ATOM   13364 C  CB  . SER E 2 362 ? 131.419 143.870 177.585 1.00 109.76 ? 308 SER C CB  1 
ATOM   13365 O  OG  . SER E 2 362 ? 130.700 144.212 176.413 1.00 110.51 ? 308 SER C OG  1 
ATOM   13366 N  N   . GLN E 2 363 ? 128.558 142.924 177.694 1.00 112.18 ? 309 GLN C N   1 
ATOM   13367 C  CA  . GLN E 2 363 ? 127.163 143.230 178.011 1.00 109.57 ? 309 GLN C CA  1 
ATOM   13368 C  C   . GLN E 2 363 ? 126.261 142.286 177.228 1.00 110.89 ? 309 GLN C C   1 
ATOM   13369 O  O   . GLN E 2 363 ? 125.746 142.644 176.161 1.00 112.29 ? 309 GLN C O   1 
ATOM   13370 C  CB  . GLN E 2 363 ? 126.842 144.690 177.694 1.00 111.56 ? 309 GLN C CB  1 
ATOM   13371 C  CG  . GLN E 2 363 ? 127.885 145.678 178.199 1.00 120.88 ? 309 GLN C CG  1 
ATOM   13372 C  CD  . GLN E 2 363 ? 127.555 147.117 177.843 1.00 132.22 ? 309 GLN C CD  1 
ATOM   13373 O  OE1 . GLN E 2 363 ? 126.475 147.411 177.332 1.00 135.18 ? 309 GLN C OE1 1 
ATOM   13374 N  NE2 . GLN E 2 363 ? 128.489 148.023 178.113 1.00 132.51 ? 309 GLN C NE2 1 
ATOM   13375 N  N   . PRO E 2 364 ? 126.049 141.067 177.731 1.00 109.84 ? 310 PRO C N   1 
ATOM   13376 C  CA  . PRO E 2 364 ? 125.178 140.120 177.014 1.00 106.63 ? 310 PRO C CA  1 
ATOM   13377 C  C   . PRO E 2 364 ? 123.762 140.628 176.813 1.00 104.63 ? 310 PRO C C   1 
ATOM   13378 O  O   . PRO E 2 364 ? 123.130 140.295 175.801 1.00 103.04 ? 310 PRO C O   1 
ATOM   13379 C  CB  . PRO E 2 364 ? 125.209 138.873 177.909 1.00 106.04 ? 310 PRO C CB  1 
ATOM   13380 C  CG  . PRO E 2 364 ? 126.473 138.998 178.685 1.00 106.58 ? 310 PRO C CG  1 
ATOM   13381 C  CD  . PRO E 2 364 ? 126.650 140.464 178.930 1.00 107.10 ? 310 PRO C CD  1 
ATOM   13382 N  N   . ALA E 2 365 ? 123.238 141.419 177.751 1.00 104.58 ? 311 ALA C N   1 
ATOM   13383 C  CA  . ALA E 2 365 ? 121.914 142.001 177.564 1.00 97.52  ? 311 ALA C CA  1 
ATOM   13384 C  C   . ALA E 2 365 ? 121.882 142.906 176.341 1.00 98.57  ? 311 ALA C C   1 
ATOM   13385 O  O   . ALA E 2 365 ? 120.943 142.851 175.539 1.00 97.93  ? 311 ALA C O   1 
ATOM   13386 C  CB  . ALA E 2 365 ? 121.499 142.774 178.814 1.00 90.91  ? 311 ALA C CB  1 
ATOM   13387 N  N   . ARG E 2 366 ? 122.910 143.738 176.170 1.00 99.44  ? 312 ARG C N   1 
ATOM   13388 C  CA  . ARG E 2 366 ? 122.983 144.557 174.967 1.00 99.84  ? 312 ARG C CA  1 
ATOM   13389 C  C   . ARG E 2 366 ? 123.204 143.707 173.725 1.00 94.75  ? 312 ARG C C   1 
ATOM   13390 O  O   . ARG E 2 366 ? 122.707 144.052 172.648 1.00 92.97  ? 312 ARG C O   1 
ATOM   13391 C  CB  . ARG E 2 366 ? 124.081 145.608 175.108 1.00 104.29 ? 312 ARG C CB  1 
ATOM   13392 C  CG  . ARG E 2 366 ? 123.641 146.822 175.899 1.00 108.48 ? 312 ARG C CG  1 
ATOM   13393 C  CD  . ARG E 2 366 ? 122.338 147.368 175.336 1.00 109.59 ? 312 ARG C CD  1 
ATOM   13394 N  NE  . ARG E 2 366 ? 121.830 148.511 176.084 1.00 114.62 ? 312 ARG C NE  1 
ATOM   13395 C  CZ  . ARG E 2 366 ? 120.787 149.239 175.711 1.00 116.33 ? 312 ARG C CZ  1 
ATOM   13396 N  NH1 . ARG E 2 366 ? 120.117 148.969 174.603 1.00 108.81 ? 312 ARG C NH1 1 
ATOM   13397 N  NH2 . ARG E 2 366 ? 120.410 150.268 176.464 1.00 121.01 ? 312 ARG C NH2 1 
ATOM   13398 N  N   . ALA E 2 367 ? 123.924 142.592 173.852 1.00 95.33  ? 313 ALA C N   1 
ATOM   13399 C  CA  . ALA E 2 367 ? 124.091 141.700 172.712 1.00 90.94  ? 313 ALA C CA  1 
ATOM   13400 C  C   . ALA E 2 367 ? 122.751 141.144 172.253 1.00 88.77  ? 313 ALA C C   1 
ATOM   13401 O  O   . ALA E 2 367 ? 122.507 141.011 171.050 1.00 86.18  ? 313 ALA C O   1 
ATOM   13402 C  CB  . ALA E 2 367 ? 125.053 140.566 173.062 1.00 92.60  ? 313 ALA C CB  1 
ATOM   13403 N  N   . ALA E 2 368 ? 121.872 140.805 173.197 1.00 88.22  ? 314 ALA C N   1 
ATOM   13404 C  CA  . ALA E 2 368 ? 120.541 140.335 172.823 1.00 84.52  ? 314 ALA C CA  1 
ATOM   13405 C  C   . ALA E 2 368 ? 119.679 141.472 172.285 1.00 83.58  ? 314 ALA C C   1 
ATOM   13406 O  O   . ALA E 2 368 ? 118.870 141.271 171.368 1.00 81.20  ? 314 ALA C O   1 
ATOM   13407 C  CB  . ALA E 2 368 ? 119.864 139.667 174.016 1.00 84.24  ? 314 ALA C CB  1 
ATOM   13408 N  N   . ALA E 2 369 ? 119.832 142.673 172.847 1.00 81.85  ? 422 ALA C N   1 
ATOM   13409 C  CA  . ALA E 2 369 ? 119.048 143.805 172.371 1.00 79.07  ? 422 ALA C CA  1 
ATOM   13410 C  C   . ALA E 2 369 ? 119.406 144.171 170.939 1.00 75.40  ? 422 ALA C C   1 
ATOM   13411 O  O   . ALA E 2 369 ? 118.539 144.614 170.178 1.00 75.85  ? 422 ALA C O   1 
ATOM   13412 C  CB  . ALA E 2 369 ? 119.238 145.007 173.295 1.00 80.09  ? 422 ALA C CB  1 
ATOM   13413 N  N   . ILE E 2 370 ? 120.672 144.004 170.553 1.00 74.75  ? 423 ILE C N   1 
ATOM   13414 C  CA  . ILE E 2 370 ? 121.053 144.283 169.170 1.00 71.93  ? 423 ILE C CA  1 
ATOM   13415 C  C   . ILE E 2 370 ? 120.322 143.347 168.218 1.00 71.05  ? 423 ILE C C   1 
ATOM   13416 O  O   . ILE E 2 370 ? 119.813 143.776 167.177 1.00 75.08  ? 423 ILE C O   1 
ATOM   13417 C  CB  . ILE E 2 370 ? 122.577 144.187 168.985 1.00 71.81  ? 423 ILE C CB  1 
ATOM   13418 C  CG1 . ILE E 2 370 ? 123.296 145.195 169.875 1.00 72.85  ? 423 ILE C CG1 1 
ATOM   13419 C  CG2 . ILE E 2 370 ? 122.940 144.465 167.547 1.00 69.54  ? 423 ILE C CG2 1 
ATOM   13420 C  CD1 . ILE E 2 370 ? 122.900 146.621 169.620 1.00 70.39  ? 423 ILE C CD1 1 
ATOM   13421 N  N   . ASP E 2 371 ? 120.255 142.058 168.554 1.00 68.62  ? 424 ASP C N   1 
ATOM   13422 C  CA  . ASP E 2 371 ? 119.511 141.123 167.715 1.00 68.63  ? 424 ASP C CA  1 
ATOM   13423 C  C   . ASP E 2 371 ? 118.034 141.485 167.664 1.00 69.17  ? 424 ASP C C   1 
ATOM   13424 O  O   . ASP E 2 371 ? 117.412 141.449 166.592 1.00 74.78  ? 424 ASP C O   1 
ATOM   13425 C  CB  . ASP E 2 371 ? 119.690 139.697 168.227 1.00 75.31  ? 424 ASP C CB  1 
ATOM   13426 C  CG  . ASP E 2 371 ? 120.984 139.066 167.760 1.00 80.69  ? 424 ASP C CG  1 
ATOM   13427 O  OD1 . ASP E 2 371 ? 121.729 139.726 167.010 1.00 84.67  ? 424 ASP C OD1 1 
ATOM   13428 O  OD2 . ASP E 2 371 ? 121.254 137.908 168.139 1.00 75.85  ? 424 ASP C OD2 1 
ATOM   13429 N  N   . ARG E 2 372 ? 117.452 141.837 168.813 1.00 67.82  ? 425 ARG C N   1 
ATOM   13430 C  CA  . ARG E 2 372 ? 116.040 142.203 168.834 1.00 68.52  ? 425 ARG C CA  1 
ATOM   13431 C  C   . ARG E 2 372 ? 115.766 143.406 167.944 1.00 69.79  ? 425 ARG C C   1 
ATOM   13432 O  O   . ARG E 2 372 ? 114.768 143.435 167.217 1.00 64.66  ? 425 ARG C O   1 
ATOM   13433 C  CB  . ARG E 2 372 ? 115.580 142.489 170.260 1.00 72.89  ? 425 ARG C CB  1 
ATOM   13434 C  CG  . ARG E 2 372 ? 115.249 141.255 171.066 1.00 77.98  ? 425 ARG C CG  1 
ATOM   13435 C  CD  . ARG E 2 372 ? 114.242 141.572 172.157 1.00 83.35  ? 425 ARG C CD  1 
ATOM   13436 N  NE  . ARG E 2 372 ? 114.749 142.565 173.094 1.00 95.33  ? 425 ARG C NE  1 
ATOM   13437 C  CZ  . ARG E 2 372 ? 115.468 142.277 174.169 1.00 97.70  ? 425 ARG C CZ  1 
ATOM   13438 N  NH1 . ARG E 2 372 ? 115.784 141.029 174.473 1.00 90.54  ? 425 ARG C NH1 1 
ATOM   13439 N  NH2 . ARG E 2 372 ? 115.882 143.264 174.957 1.00 97.48  ? 425 ARG C NH2 1 
ATOM   13440 N  N   . TRP E 2 373 ? 116.637 144.414 167.991 1.00 71.84  ? 426 TRP C N   1 
ATOM   13441 C  CA  . TRP E 2 373 ? 116.445 145.579 167.137 1.00 69.89  ? 426 TRP C CA  1 
ATOM   13442 C  C   . TRP E 2 373 ? 116.661 145.237 165.670 1.00 64.53  ? 426 TRP C C   1 
ATOM   13443 O  O   . TRP E 2 373 ? 115.946 145.747 164.802 1.00 67.28  ? 426 TRP C O   1 
ATOM   13444 C  CB  . TRP E 2 373 ? 117.372 146.713 167.565 1.00 74.81  ? 426 TRP C CB  1 
ATOM   13445 C  CG  . TRP E 2 373 ? 116.805 147.547 168.667 1.00 85.50  ? 426 TRP C CG  1 
ATOM   13446 C  CD1 . TRP E 2 373 ? 117.313 147.702 169.920 1.00 83.25  ? 426 TRP C CD1 1 
ATOM   13447 C  CD2 . TRP E 2 373 ? 115.608 148.331 168.618 1.00 91.36  ? 426 TRP C CD2 1 
ATOM   13448 N  NE1 . TRP E 2 373 ? 116.513 148.541 170.655 1.00 87.43  ? 426 TRP C NE1 1 
ATOM   13449 C  CE2 . TRP E 2 373 ? 115.458 148.940 169.878 1.00 92.28  ? 426 TRP C CE2 1 
ATOM   13450 C  CE3 . TRP E 2 373 ? 114.651 148.582 167.631 1.00 88.01  ? 426 TRP C CE3 1 
ATOM   13451 C  CZ2 . TRP E 2 373 ? 114.391 149.783 170.177 1.00 91.77  ? 426 TRP C CZ2 1 
ATOM   13452 C  CZ3 . TRP E 2 373 ? 113.592 149.416 167.929 1.00 89.21  ? 426 TRP C CZ3 1 
ATOM   13453 C  CH2 . TRP E 2 373 ? 113.470 150.007 169.192 1.00 90.33  ? 426 TRP C CH2 1 
ATOM   13454 N  N   . SER E 2 374 ? 117.645 144.384 165.372 1.00 60.19  ? 427 SER C N   1 
ATOM   13455 C  CA  . SER E 2 374 ? 117.921 144.030 163.984 1.00 54.60  ? 427 SER C CA  1 
ATOM   13456 C  C   . SER E 2 374 ? 116.737 143.319 163.355 1.00 57.28  ? 427 SER C C   1 
ATOM   13457 O  O   . SER E 2 374 ? 116.431 143.541 162.176 1.00 59.48  ? 427 SER C O   1 
ATOM   13458 C  CB  . SER E 2 374 ? 119.170 143.160 163.902 1.00 57.17  ? 427 SER C CB  1 
ATOM   13459 O  OG  . SER E 2 374 ? 120.267 143.809 164.511 1.00 67.50  ? 427 SER C OG  1 
ATOM   13460 N  N   . ARG E 2 375 ? 116.039 142.490 164.141 1.00 58.08  ? 428 ARG C N   1 
ATOM   13461 C  CA  . ARG E 2 375 ? 114.887 141.756 163.622 1.00 53.58  ? 428 ARG C CA  1 
ATOM   13462 C  C   . ARG E 2 375 ? 113.860 142.682 162.990 1.00 56.80  ? 428 ARG C C   1 
ATOM   13463 O  O   . ARG E 2 375 ? 113.125 142.270 162.088 1.00 59.66  ? 428 ARG C O   1 
ATOM   13464 C  CB  . ARG E 2 375 ? 114.216 140.948 164.732 1.00 50.98  ? 428 ARG C CB  1 
ATOM   13465 C  CG  . ARG E 2 375 ? 115.034 139.805 165.279 1.00 56.36  ? 428 ARG C CG  1 
ATOM   13466 C  CD  . ARG E 2 375 ? 114.206 138.982 166.248 1.00 57.77  ? 428 ARG C CD  1 
ATOM   13467 N  NE  . ARG E 2 375 ? 114.984 137.928 166.884 1.00 59.87  ? 428 ARG C NE  1 
ATOM   13468 C  CZ  . ARG E 2 375 ? 115.252 137.875 168.180 1.00 61.48  ? 428 ARG C CZ  1 
ATOM   13469 N  NH1 . ARG E 2 375 ? 114.813 138.801 169.012 1.00 69.20  ? 428 ARG C NH1 1 
ATOM   13470 N  NH2 . ARG E 2 375 ? 115.969 136.862 168.653 1.00 61.15  ? 428 ARG C NH2 1 
ATOM   13471 N  N   . ILE E 2 376 ? 113.780 143.923 163.456 1.00 56.97  ? 429 ILE C N   1 
ATOM   13472 C  CA  . ILE E 2 376 ? 112.850 144.901 162.912 1.00 51.49  ? 429 ILE C CA  1 
ATOM   13473 C  C   . ILE E 2 376 ? 113.529 145.831 161.917 1.00 53.62  ? 429 ILE C C   1 
ATOM   13474 O  O   . ILE E 2 376 ? 112.931 146.207 160.909 1.00 58.10  ? 429 ILE C O   1 
ATOM   13475 C  CB  . ILE E 2 376 ? 112.199 145.698 164.061 1.00 50.69  ? 429 ILE C CB  1 
ATOM   13476 C  CG1 . ILE E 2 376 ? 111.568 144.744 165.069 1.00 54.67  ? 429 ILE C CG1 1 
ATOM   13477 C  CG2 . ILE E 2 376 ? 111.165 146.664 163.527 1.00 51.41  ? 429 ILE C CG2 1 
ATOM   13478 C  CD1 . ILE E 2 376 ? 110.972 145.439 166.267 1.00 58.11  ? 429 ILE C CD1 1 
ATOM   13479 N  N   . VAL E 2 377 ? 114.778 146.207 162.184 1.00 54.34  ? 430 VAL C N   1 
ATOM   13480 C  CA  . VAL E 2 377 ? 115.455 147.199 161.356 1.00 52.19  ? 430 VAL C CA  1 
ATOM   13481 C  C   . VAL E 2 377 ? 115.738 146.647 159.964 1.00 55.35  ? 430 VAL C C   1 
ATOM   13482 O  O   . VAL E 2 377 ? 115.507 147.326 158.959 1.00 57.41  ? 430 VAL C O   1 
ATOM   13483 C  CB  . VAL E 2 377 ? 116.742 147.682 162.046 1.00 48.61  ? 430 VAL C CB  1 
ATOM   13484 C  CG1 . VAL E 2 377 ? 117.597 148.468 161.081 1.00 44.34  ? 430 VAL C CG1 1 
ATOM   13485 C  CG2 . VAL E 2 377 ? 116.398 148.534 163.246 1.00 49.10  ? 430 VAL C CG2 1 
ATOM   13486 N  N   . PHE E 2 378 ? 116.255 145.419 159.876 1.00 55.82  ? 431 PHE C N   1 
ATOM   13487 C  CA  . PHE E 2 378 ? 116.663 144.905 158.568 1.00 52.52  ? 431 PHE C CA  1 
ATOM   13488 C  C   . PHE E 2 378 ? 115.504 144.752 157.590 1.00 51.69  ? 431 PHE C C   1 
ATOM   13489 O  O   . PHE E 2 378 ? 115.610 145.271 156.464 1.00 54.10  ? 431 PHE C O   1 
ATOM   13490 C  CB  . PHE E 2 378 ? 117.427 143.589 158.736 1.00 50.90  ? 431 PHE C CB  1 
ATOM   13491 C  CG  . PHE E 2 378 ? 118.893 143.765 158.962 1.00 51.21  ? 431 PHE C CG  1 
ATOM   13492 C  CD1 . PHE E 2 378 ? 119.395 143.918 160.237 1.00 54.96  ? 431 PHE C CD1 1 
ATOM   13493 C  CD2 . PHE E 2 378 ? 119.772 143.765 157.899 1.00 49.95  ? 431 PHE C CD2 1 
ATOM   13494 C  CE1 . PHE E 2 378 ? 120.747 144.078 160.448 1.00 59.70  ? 431 PHE C CE1 1 
ATOM   13495 C  CE2 . PHE E 2 378 ? 121.124 143.921 158.104 1.00 52.26  ? 431 PHE C CE2 1 
ATOM   13496 C  CZ  . PHE E 2 378 ? 121.612 144.078 159.380 1.00 58.18  ? 431 PHE C CZ  1 
ATOM   13497 N  N   . PRO E 2 379 ? 114.397 144.070 157.920 1.00 48.26  ? 432 PRO C N   1 
ATOM   13498 C  CA  . PRO E 2 379 ? 113.293 143.997 156.950 1.00 50.44  ? 432 PRO C CA  1 
ATOM   13499 C  C   . PRO E 2 379 ? 112.745 145.353 156.551 1.00 52.60  ? 432 PRO C C   1 
ATOM   13500 O  O   . PRO E 2 379 ? 112.437 145.575 155.374 1.00 52.82  ? 432 PRO C O   1 
ATOM   13501 C  CB  . PRO E 2 379 ? 112.243 143.159 157.687 1.00 50.07  ? 432 PRO C CB  1 
ATOM   13502 C  CG  . PRO E 2 379 ? 113.011 142.365 158.658 1.00 47.33  ? 432 PRO C CG  1 
ATOM   13503 C  CD  . PRO E 2 379 ? 114.112 143.255 159.113 1.00 45.86  ? 432 PRO C CD  1 
ATOM   13504 N  N   . PHE E 2 380 ? 112.630 146.278 157.503 1.00 49.07  ? 433 PHE C N   1 
ATOM   13505 C  CA  . PHE E 2 380 ? 112.067 147.588 157.201 1.00 50.97  ? 433 PHE C CA  1 
ATOM   13506 C  C   . PHE E 2 380 ? 112.971 148.374 156.261 1.00 53.15  ? 433 PHE C C   1 
ATOM   13507 O  O   . PHE E 2 380 ? 112.504 148.962 155.277 1.00 58.17  ? 433 PHE C O   1 
ATOM   13508 C  CB  . PHE E 2 380 ? 111.832 148.361 158.497 1.00 54.10  ? 433 PHE C CB  1 
ATOM   13509 C  CG  . PHE E 2 380 ? 111.279 149.739 158.289 1.00 62.30  ? 433 PHE C CG  1 
ATOM   13510 C  CD1 . PHE E 2 380 ? 109.933 149.925 158.039 1.00 62.65  ? 433 PHE C CD1 1 
ATOM   13511 C  CD2 . PHE E 2 380 ? 112.101 150.848 158.351 1.00 63.14  ? 433 PHE C CD2 1 
ATOM   13512 C  CE1 . PHE E 2 380 ? 109.418 151.189 157.849 1.00 64.70  ? 433 PHE C CE1 1 
ATOM   13513 C  CE2 . PHE E 2 380 ? 111.593 152.111 158.161 1.00 67.41  ? 433 PHE C CE2 1 
ATOM   13514 C  CZ  . PHE E 2 380 ? 110.248 152.282 157.911 1.00 68.14  ? 433 PHE C CZ  1 
ATOM   13515 N  N   . THR E 2 381 ? 114.271 148.397 156.548 1.00 52.24  ? 434 THR C N   1 
ATOM   13516 C  CA  . THR E 2 381 ? 115.195 149.127 155.691 1.00 54.07  ? 434 THR C CA  1 
ATOM   13517 C  C   . THR E 2 381 ? 115.284 148.492 154.310 1.00 54.22  ? 434 THR C C   1 
ATOM   13518 O  O   . THR E 2 381 ? 115.383 149.201 153.306 1.00 55.38  ? 434 THR C O   1 
ATOM   13519 C  CB  . THR E 2 381 ? 116.572 149.208 156.345 1.00 53.56  ? 434 THR C CB  1 
ATOM   13520 O  OG1 . THR E 2 381 ? 116.461 149.881 157.603 1.00 56.32  ? 434 THR C OG1 1 
ATOM   13521 C  CG2 . THR E 2 381 ? 117.529 149.984 155.469 1.00 54.32  ? 434 THR C CG2 1 
ATOM   13522 N  N   . PHE E 2 382 ? 115.236 147.162 154.230 1.00 49.79  ? 435 PHE C N   1 
ATOM   13523 C  CA  . PHE E 2 382 ? 115.249 146.520 152.919 1.00 46.73  ? 435 PHE C CA  1 
ATOM   13524 C  C   . PHE E 2 382 ? 113.992 146.846 152.121 1.00 50.47  ? 435 PHE C C   1 
ATOM   13525 O  O   . PHE E 2 382 ? 114.065 147.077 150.908 1.00 50.90  ? 435 PHE C O   1 
ATOM   13526 C  CB  . PHE E 2 382 ? 115.407 145.014 153.076 1.00 48.21  ? 435 PHE C CB  1 
ATOM   13527 C  CG  . PHE E 2 382 ? 115.673 144.298 151.790 1.00 51.43  ? 435 PHE C CG  1 
ATOM   13528 C  CD1 . PHE E 2 382 ? 116.859 144.489 151.113 1.00 48.72  ? 435 PHE C CD1 1 
ATOM   13529 C  CD2 . PHE E 2 382 ? 114.748 143.419 151.268 1.00 48.40  ? 435 PHE C CD2 1 
ATOM   13530 C  CE1 . PHE E 2 382 ? 117.112 143.830 149.938 1.00 45.11  ? 435 PHE C CE1 1 
ATOM   13531 C  CE2 . PHE E 2 382 ? 115.000 142.754 150.090 1.00 44.38  ? 435 PHE C CE2 1 
ATOM   13532 C  CZ  . PHE E 2 382 ? 116.182 142.961 149.424 1.00 41.26  ? 435 PHE C CZ  1 
ATOM   13533 N  N   . SER E 2 383 ? 112.828 146.865 152.774 1.00 54.35  ? 436 SER C N   1 
ATOM   13534 C  CA  . SER E 2 383 ? 111.608 147.257 152.074 1.00 52.57  ? 436 SER C CA  1 
ATOM   13535 C  C   . SER E 2 383 ? 111.695 148.695 151.581 1.00 51.80  ? 436 SER C C   1 
ATOM   13536 O  O   . SER E 2 383 ? 111.307 148.996 150.446 1.00 57.91  ? 436 SER C O   1 
ATOM   13537 C  CB  . SER E 2 383 ? 110.398 147.078 152.986 1.00 53.72  ? 436 SER C CB  1 
ATOM   13538 O  OG  . SER E 2 383 ? 110.313 145.747 153.460 1.00 61.74  ? 436 SER C OG  1 
ATOM   13539 N  N   . LEU E 2 384 ? 112.214 149.595 152.416 1.00 53.76  ? 437 LEU C N   1 
ATOM   13540 C  CA  . LEU E 2 384 ? 112.369 150.984 151.995 1.00 55.26  ? 437 LEU C CA  1 
ATOM   13541 C  C   . LEU E 2 384 ? 113.345 151.102 150.832 1.00 53.04  ? 437 LEU C C   1 
ATOM   13542 O  O   . LEU E 2 384 ? 113.144 151.912 149.921 1.00 56.80  ? 437 LEU C O   1 
ATOM   13543 C  CB  . LEU E 2 384 ? 112.831 151.836 153.174 1.00 53.34  ? 437 LEU C CB  1 
ATOM   13544 C  CG  . LEU E 2 384 ? 112.402 153.297 153.143 1.00 57.52  ? 437 LEU C CG  1 
ATOM   13545 C  CD1 . LEU E 2 384 ? 110.896 153.406 153.003 1.00 52.45  ? 437 LEU C CD1 1 
ATOM   13546 C  CD2 . LEU E 2 384 ? 112.863 153.992 154.399 1.00 58.17  ? 437 LEU C CD2 1 
ATOM   13547 N  N   . PHE E 2 385 ? 114.413 150.305 150.850 1.00 48.68  ? 438 PHE C N   1 
ATOM   13548 C  CA  . PHE E 2 385 ? 115.383 150.316 149.762 1.00 49.10  ? 438 PHE C CA  1 
ATOM   13549 C  C   . PHE E 2 385 ? 114.766 149.831 148.458 1.00 51.62  ? 438 PHE C C   1 
ATOM   13550 O  O   . PHE E 2 385 ? 115.011 150.410 147.396 1.00 51.68  ? 438 PHE C O   1 
ATOM   13551 C  CB  . PHE E 2 385 ? 116.584 149.458 150.148 1.00 52.98  ? 438 PHE C CB  1 
ATOM   13552 C  CG  . PHE E 2 385 ? 117.532 149.192 149.025 1.00 54.03  ? 438 PHE C CG  1 
ATOM   13553 C  CD1 . PHE E 2 385 ? 118.288 150.211 148.485 1.00 55.44  ? 438 PHE C CD1 1 
ATOM   13554 C  CD2 . PHE E 2 385 ? 117.694 147.913 148.531 1.00 50.72  ? 438 PHE C CD2 1 
ATOM   13555 C  CE1 . PHE E 2 385 ? 119.168 149.962 147.461 1.00 53.78  ? 438 PHE C CE1 1 
ATOM   13556 C  CE2 . PHE E 2 385 ? 118.574 147.664 147.509 1.00 50.84  ? 438 PHE C CE2 1 
ATOM   13557 C  CZ  . PHE E 2 385 ? 119.310 148.690 146.973 1.00 47.79  ? 438 PHE C CZ  1 
ATOM   13558 N  N   . ASN E 2 386 ? 113.968 148.762 148.516 1.00 52.91  ? 439 ASN C N   1 
ATOM   13559 C  CA  . ASN E 2 386 ? 113.277 148.300 147.316 1.00 48.57  ? 439 ASN C CA  1 
ATOM   13560 C  C   . ASN E 2 386 ? 112.311 149.357 146.801 1.00 52.70  ? 439 ASN C C   1 
ATOM   13561 O  O   . ASN E 2 386 ? 112.201 149.572 145.589 1.00 60.30  ? 439 ASN C O   1 
ATOM   13562 C  CB  . ASN E 2 386 ? 112.540 146.993 147.592 1.00 40.15  ? 439 ASN C CB  1 
ATOM   13563 C  CG  . ASN E 2 386 ? 113.438 145.782 147.480 1.00 49.00  ? 439 ASN C CG  1 
ATOM   13564 O  OD1 . ASN E 2 386 ? 113.585 145.203 146.408 1.00 48.32  ? 439 ASN C OD1 1 
ATOM   13565 N  ND2 . ASN E 2 386 ? 114.044 145.391 148.588 1.00 56.76  ? 439 ASN C ND2 1 
ATOM   13566 N  N   . LEU E 2 387 ? 111.599 150.027 147.708 1.00 53.39  ? 440 LEU C N   1 
ATOM   13567 C  CA  . LEU E 2 387 ? 110.685 151.085 147.291 1.00 51.55  ? 440 LEU C CA  1 
ATOM   13568 C  C   . LEU E 2 387 ? 111.431 152.224 146.604 1.00 55.85  ? 440 LEU C C   1 
ATOM   13569 O  O   . LEU E 2 387 ? 110.994 152.722 145.561 1.00 59.16  ? 440 LEU C O   1 
ATOM   13570 C  CB  . LEU E 2 387 ? 109.909 151.602 148.498 1.00 54.87  ? 440 LEU C CB  1 
ATOM   13571 C  CG  . LEU E 2 387 ? 108.838 152.648 148.214 1.00 64.12  ? 440 LEU C CG  1 
ATOM   13572 C  CD1 . LEU E 2 387 ? 107.690 152.025 147.444 1.00 67.09  ? 440 LEU C CD1 1 
ATOM   13573 C  CD2 . LEU E 2 387 ? 108.346 153.275 149.506 1.00 62.23  ? 440 LEU C CD2 1 
ATOM   13574 N  N   . VAL E 2 388 ? 112.563 152.643 147.171 1.00 57.16  ? 441 VAL C N   1 
ATOM   13575 C  CA  . VAL E 2 388 ? 113.357 153.709 146.565 1.00 60.18  ? 441 VAL C CA  1 
ATOM   13576 C  C   . VAL E 2 388 ? 113.856 153.287 145.191 1.00 60.60  ? 441 VAL C C   1 
ATOM   13577 O  O   . VAL E 2 388 ? 113.807 154.064 144.228 1.00 62.79  ? 441 VAL C O   1 
ATOM   13578 C  CB  . VAL E 2 388 ? 114.522 154.096 147.492 1.00 56.96  ? 441 VAL C CB  1 
ATOM   13579 C  CG1 . VAL E 2 388 ? 115.633 154.766 146.702 1.00 51.30  ? 441 VAL C CG1 1 
ATOM   13580 C  CG2 . VAL E 2 388 ? 114.035 155.008 148.595 1.00 51.57  ? 441 VAL C CG2 1 
ATOM   13581 N  N   . TYR E 2 389 ? 114.337 152.048 145.076 1.00 56.88  ? 442 TYR C N   1 
ATOM   13582 C  CA  . TYR E 2 389 ? 114.840 151.574 143.793 1.00 53.31  ? 442 TYR C CA  1 
ATOM   13583 C  C   . TYR E 2 389 ? 113.744 151.554 142.740 1.00 57.35  ? 442 TYR C C   1 
ATOM   13584 O  O   . TYR E 2 389 ? 113.976 151.933 141.588 1.00 65.78  ? 442 TYR C O   1 
ATOM   13585 C  CB  . TYR E 2 389 ? 115.452 150.188 143.943 1.00 52.63  ? 442 TYR C CB  1 
ATOM   13586 C  CG  . TYR E 2 389 ? 115.748 149.534 142.621 1.00 51.94  ? 442 TYR C CG  1 
ATOM   13587 C  CD1 . TYR E 2 389 ? 116.797 149.969 141.835 1.00 51.03  ? 442 TYR C CD1 1 
ATOM   13588 C  CD2 . TYR E 2 389 ? 114.974 148.485 142.157 1.00 53.56  ? 442 TYR C CD2 1 
ATOM   13589 C  CE1 . TYR E 2 389 ? 117.069 149.378 140.628 1.00 53.05  ? 442 TYR C CE1 1 
ATOM   13590 C  CE2 . TYR E 2 389 ? 115.240 147.885 140.949 1.00 52.69  ? 442 TYR C CE2 1 
ATOM   13591 C  CZ  . TYR E 2 389 ? 116.287 148.336 140.189 1.00 54.55  ? 442 TYR C CZ  1 
ATOM   13592 O  OH  . TYR E 2 389 ? 116.553 147.738 138.982 1.00 58.72  ? 442 TYR C OH  1 
ATOM   13593 N  N   . TRP E 2 390 ? 112.542 151.111 143.108 1.00 57.79  ? 443 TRP C N   1 
ATOM   13594 C  CA  . TRP E 2 390 ? 111.475 151.052 142.119 1.00 58.86  ? 443 TRP C CA  1 
ATOM   13595 C  C   . TRP E 2 390 ? 110.909 152.423 141.794 1.00 62.43  ? 443 TRP C C   1 
ATOM   13596 O  O   . TRP E 2 390 ? 110.360 152.606 140.705 1.00 67.31  ? 443 TRP C O   1 
ATOM   13597 C  CB  . TRP E 2 390 ? 110.361 150.116 142.582 1.00 56.40  ? 443 TRP C CB  1 
ATOM   13598 C  CG  . TRP E 2 390 ? 110.715 148.687 142.399 1.00 54.92  ? 443 TRP C CG  1 
ATOM   13599 C  CD1 . TRP E 2 390 ? 110.858 147.751 143.370 1.00 53.62  ? 443 TRP C CD1 1 
ATOM   13600 C  CD2 . TRP E 2 390 ? 111.007 148.031 141.161 1.00 63.51  ? 443 TRP C CD2 1 
ATOM   13601 N  NE1 . TRP E 2 390 ? 111.208 146.545 142.818 1.00 57.34  ? 443 TRP C NE1 1 
ATOM   13602 C  CE2 . TRP E 2 390 ? 111.307 146.692 141.461 1.00 63.20  ? 443 TRP C CE2 1 
ATOM   13603 C  CE3 . TRP E 2 390 ? 111.036 148.445 139.827 1.00 65.89  ? 443 TRP C CE3 1 
ATOM   13604 C  CZ2 . TRP E 2 390 ? 111.629 145.762 140.477 1.00 59.19  ? 443 TRP C CZ2 1 
ATOM   13605 C  CZ3 . TRP E 2 390 ? 111.359 147.523 138.855 1.00 66.12  ? 443 TRP C CZ3 1 
ATOM   13606 C  CH2 . TRP E 2 390 ? 111.650 146.197 139.183 1.00 65.36  ? 443 TRP C CH2 1 
ATOM   13607 N  N   . LEU E 2 391 ? 111.020 153.386 142.705 1.00 63.96  ? 444 LEU C N   1 
ATOM   13608 C  CA  . LEU E 2 391 ? 110.610 154.744 142.379 1.00 65.35  ? 444 LEU C CA  1 
ATOM   13609 C  C   . LEU E 2 391 ? 111.702 155.530 141.672 1.00 68.79  ? 444 LEU C C   1 
ATOM   13610 O  O   . LEU E 2 391 ? 111.441 156.648 141.217 1.00 73.45  ? 444 LEU C O   1 
ATOM   13611 C  CB  . LEU E 2 391 ? 110.169 155.488 143.638 1.00 66.64  ? 444 LEU C CB  1 
ATOM   13612 C  CG  . LEU E 2 391 ? 108.913 154.915 144.295 1.00 66.66  ? 444 LEU C CG  1 
ATOM   13613 C  CD1 . LEU E 2 391 ? 108.348 155.889 145.313 1.00 69.43  ? 444 LEU C CD1 1 
ATOM   13614 C  CD2 . LEU E 2 391 ? 107.869 154.550 143.254 1.00 55.29  ? 444 LEU C CD2 1 
ATOM   13615 N  N   . TYR E 2 392 ? 112.916 154.986 141.580 1.00 71.22  ? 445 TYR C N   1 
ATOM   13616 C  CA  . TYR E 2 392 ? 113.925 155.604 140.728 1.00 71.01  ? 445 TYR C CA  1 
ATOM   13617 C  C   . TYR E 2 392 ? 113.491 155.593 139.270 1.00 71.94  ? 445 TYR C C   1 
ATOM   13618 O  O   . TYR E 2 392 ? 113.745 156.551 138.531 1.00 74.45  ? 445 TYR C O   1 
ATOM   13619 C  CB  . TYR E 2 392 ? 115.265 154.891 140.878 1.00 69.25  ? 445 TYR C CB  1 
ATOM   13620 C  CG  . TYR E 2 392 ? 116.238 155.263 139.791 1.00 77.70  ? 445 TYR C CG  1 
ATOM   13621 C  CD1 . TYR E 2 392 ? 116.928 156.463 139.839 1.00 81.16  ? 445 TYR C CD1 1 
ATOM   13622 C  CD2 . TYR E 2 392 ? 116.453 154.426 138.704 1.00 78.41  ? 445 TYR C CD2 1 
ATOM   13623 C  CE1 . TYR E 2 392 ? 117.811 156.817 138.846 1.00 83.91  ? 445 TYR C CE1 1 
ATOM   13624 C  CE2 . TYR E 2 392 ? 117.336 154.774 137.702 1.00 81.13  ? 445 TYR C CE2 1 
ATOM   13625 C  CZ  . TYR E 2 392 ? 118.012 155.971 137.780 1.00 88.96  ? 445 TYR C CZ  1 
ATOM   13626 O  OH  . TYR E 2 392 ? 118.895 156.324 136.789 1.00 91.21  ? 445 TYR C OH  1 
ATOM   13627 N  N   . TYR E 2 393 ? 112.849 154.510 138.832 1.00 69.92  ? 446 TYR C N   1 
ATOM   13628 C  CA  . TYR E 2 393 ? 112.420 154.393 137.445 1.00 71.36  ? 446 TYR C CA  1 
ATOM   13629 C  C   . TYR E 2 393 ? 111.264 155.317 137.097 1.00 74.01  ? 446 TYR C C   1 
ATOM   13630 O  O   . TYR E 2 393 ? 110.911 155.416 135.919 1.00 71.32  ? 446 TYR C O   1 
ATOM   13631 C  CB  . TYR E 2 393 ? 112.033 152.949 137.136 1.00 69.69  ? 446 TYR C CB  1 
ATOM   13632 C  CG  . TYR E 2 393 ? 113.215 152.016 137.073 1.00 70.08  ? 446 TYR C CG  1 
ATOM   13633 C  CD1 . TYR E 2 393 ? 114.374 152.378 136.409 1.00 66.85  ? 446 TYR C CD1 1 
ATOM   13634 C  CD2 . TYR E 2 393 ? 113.177 150.781 137.691 1.00 66.45  ? 446 TYR C CD2 1 
ATOM   13635 C  CE1 . TYR E 2 393 ? 115.455 151.531 136.355 1.00 63.99  ? 446 TYR C CE1 1 
ATOM   13636 C  CE2 . TYR E 2 393 ? 114.252 149.932 137.642 1.00 65.04  ? 446 TYR C CE2 1 
ATOM   13637 C  CZ  . TYR E 2 393 ? 115.387 150.308 136.976 1.00 65.04  ? 446 TYR C CZ  1 
ATOM   13638 O  OH  . TYR E 2 393 ? 116.460 149.452 136.931 1.00 65.82  ? 446 TYR C OH  1 
ATOM   13639 N  N   . VAL E 2 394 ? 110.660 155.976 138.078 1.00 79.66  ? 447 VAL C N   1 
ATOM   13640 C  CA  . VAL E 2 394 ? 109.563 156.896 137.815 1.00 78.81  ? 447 VAL C CA  1 
ATOM   13641 C  C   . VAL E 2 394 ? 110.007 158.330 138.070 1.00 72.55  ? 447 VAL C C   1 
ATOM   13642 O  O   . VAL E 2 394 ? 110.353 159.055 137.140 1.00 71.28  ? 447 VAL C O   1 
ATOM   13643 C  CB  . VAL E 2 394 ? 108.332 156.552 138.662 1.00 74.94  ? 447 VAL C CB  1 
ATOM   13644 C  CG1 . VAL E 2 394 ? 107.186 157.470 138.308 1.00 72.37  ? 447 VAL C CG1 1 
ATOM   13645 C  CG2 . VAL E 2 394 ? 107.940 155.101 138.456 1.00 71.86  ? 447 VAL C CG2 1 
ATOM   13646 N  N   . GLN F 3 1   ? 112.305 161.852 118.927 1.00 79.23  ? 2   GLN F N   1 
ATOM   13647 C  CA  . GLN F 3 1   ? 112.494 163.223 118.476 1.00 81.36  ? 2   GLN F CA  1 
ATOM   13648 C  C   . GLN F 3 1   ? 113.466 163.959 119.395 1.00 88.06  ? 2   GLN F C   1 
ATOM   13649 O  O   . GLN F 3 1   ? 113.410 163.811 120.614 1.00 90.76  ? 2   GLN F O   1 
ATOM   13650 C  CB  . GLN F 3 1   ? 111.149 163.947 118.410 1.00 84.49  ? 2   GLN F CB  1 
ATOM   13651 C  CG  . GLN F 3 1   ? 111.227 165.379 117.908 1.00 88.94  ? 2   GLN F CG  1 
ATOM   13652 C  CD  . GLN F 3 1   ? 111.254 166.397 119.033 1.00 94.81  ? 2   GLN F CD  1 
ATOM   13653 O  OE1 . GLN F 3 1   ? 110.972 166.074 120.187 1.00 94.75  ? 2   GLN F OE1 1 
ATOM   13654 N  NE2 . GLN F 3 1   ? 111.593 167.636 118.700 1.00 93.61  ? 2   GLN F NE2 1 
ATOM   13655 N  N   . VAL F 3 2   ? 114.355 164.751 118.801 1.00 84.78  ? 3   VAL F N   1 
ATOM   13656 C  CA  . VAL F 3 2   ? 115.443 165.412 119.514 1.00 82.75  ? 3   VAL F CA  1 
ATOM   13657 C  C   . VAL F 3 2   ? 115.292 166.918 119.350 1.00 84.18  ? 3   VAL F C   1 
ATOM   13658 O  O   . VAL F 3 2   ? 115.164 167.416 118.226 1.00 83.80  ? 3   VAL F O   1 
ATOM   13659 C  CB  . VAL F 3 2   ? 116.815 164.938 119.001 1.00 75.61  ? 3   VAL F CB  1 
ATOM   13660 C  CG1 . VAL F 3 2   ? 117.928 165.757 119.607 1.00 76.60  ? 3   VAL F CG1 1 
ATOM   13661 C  CG2 . VAL F 3 2   ? 117.011 163.476 119.314 1.00 73.20  ? 3   VAL F CG2 1 
ATOM   13662 N  N   . GLN F 3 3   ? 115.310 167.637 120.467 1.00 87.24  ? 4   GLN F N   1 
ATOM   13663 C  CA  . GLN F 3 3   ? 115.210 169.089 120.468 1.00 89.40  ? 4   GLN F CA  1 
ATOM   13664 C  C   . GLN F 3 3   ? 116.582 169.696 120.723 1.00 88.61  ? 4   GLN F C   1 
ATOM   13665 O  O   . GLN F 3 3   ? 117.319 169.240 121.601 1.00 86.95  ? 4   GLN F O   1 
ATOM   13666 C  CB  . GLN F 3 3   ? 114.222 169.579 121.530 1.00 93.12  ? 4   GLN F CB  1 
ATOM   13667 C  CG  . GLN F 3 3   ? 112.881 168.862 121.528 1.00 96.22  ? 4   GLN F CG  1 
ATOM   13668 C  CD  . GLN F 3 3   ? 112.867 167.643 122.432 1.00 98.62  ? 4   GLN F CD  1 
ATOM   13669 O  OE1 . GLN F 3 3   ? 113.750 167.467 123.270 1.00 100.17 ? 4   GLN F OE1 1 
ATOM   13670 N  NE2 . GLN F 3 3   ? 111.860 166.794 122.265 1.00 96.26  ? 4   GLN F NE2 1 
ATOM   13671 N  N   . LEU F 3 4   ? 116.916 170.733 119.960 1.00 88.94  ? 5   LEU F N   1 
ATOM   13672 C  CA  . LEU F 3 4   ? 118.226 171.364 120.021 1.00 89.96  ? 5   LEU F CA  1 
ATOM   13673 C  C   . LEU F 3 4   ? 118.096 172.838 120.383 1.00 95.46  ? 5   LEU F C   1 
ATOM   13674 O  O   . LEU F 3 4   ? 117.209 173.538 119.882 1.00 98.24  ? 5   LEU F O   1 
ATOM   13675 C  CB  . LEU F 3 4   ? 118.971 171.222 118.692 1.00 87.04  ? 5   LEU F CB  1 
ATOM   13676 C  CG  . LEU F 3 4   ? 119.542 169.847 118.338 1.00 83.91  ? 5   LEU F CG  1 
ATOM   13677 C  CD1 . LEU F 3 4   ? 118.467 168.912 117.820 1.00 77.55  ? 5   LEU F CD1 1 
ATOM   13678 C  CD2 . LEU F 3 4   ? 120.640 169.996 117.319 1.00 71.81  ? 5   LEU F CD2 1 
ATOM   13679 N  N   . VAL F 3 5   ? 118.992 173.298 121.253 1.00 95.90  ? 6   VAL F N   1 
ATOM   13680 C  CA  . VAL F 3 5   ? 119.006 174.667 121.755 1.00 96.29  ? 6   VAL F CA  1 
ATOM   13681 C  C   . VAL F 3 5   ? 120.381 175.259 121.487 1.00 95.89  ? 6   VAL F C   1 
ATOM   13682 O  O   . VAL F 3 5   ? 121.399 174.606 121.736 1.00 93.06  ? 6   VAL F O   1 
ATOM   13683 C  CB  . VAL F 3 5   ? 118.679 174.724 123.259 1.00 97.14  ? 6   VAL F CB  1 
ATOM   13684 C  CG1 . VAL F 3 5   ? 118.844 176.141 123.791 1.00 97.19  ? 6   VAL F CG1 1 
ATOM   13685 C  CG2 . VAL F 3 5   ? 117.272 174.212 123.512 1.00 94.44  ? 6   VAL F CG2 1 
ATOM   13686 N  N   . GLU F 3 6   ? 120.409 176.493 120.992 1.00 98.76  ? 7   GLU F N   1 
ATOM   13687 C  CA  . GLU F 3 6   ? 121.638 177.159 120.582 1.00 96.25  ? 7   GLU F CA  1 
ATOM   13688 C  C   . GLU F 3 6   ? 121.965 178.303 121.531 1.00 96.31  ? 7   GLU F C   1 
ATOM   13689 O  O   . GLU F 3 6   ? 121.096 179.122 121.848 1.00 96.78  ? 7   GLU F O   1 
ATOM   13690 C  CB  . GLU F 3 6   ? 121.507 177.694 119.157 1.00 96.15  ? 7   GLU F CB  1 
ATOM   13691 C  CG  . GLU F 3 6   ? 121.097 176.649 118.152 1.00 97.28  ? 7   GLU F CG  1 
ATOM   13692 C  CD  . GLU F 3 6   ? 122.275 175.905 117.583 1.00 92.37  ? 7   GLU F CD  1 
ATOM   13693 O  OE1 . GLU F 3 6   ? 123.392 176.073 118.110 1.00 90.00  ? 7   GLU F OE1 1 
ATOM   13694 O  OE2 . GLU F 3 6   ? 122.084 175.156 116.605 1.00 87.11  ? 7   GLU F OE2 1 
ATOM   13695 N  N   . SER F 3 7   ? 123.223 178.370 121.960 1.00 94.92  ? 8   SER F N   1 
ATOM   13696 C  CA  . SER F 3 7   ? 123.689 179.430 122.839 1.00 96.17  ? 8   SER F CA  1 
ATOM   13697 C  C   . SER F 3 7   ? 125.021 179.953 122.325 1.00 94.27  ? 8   SER F C   1 
ATOM   13698 O  O   . SER F 3 7   ? 125.865 179.176 121.872 1.00 92.25  ? 8   SER F O   1 
ATOM   13699 C  CB  . SER F 3 7   ? 123.843 178.931 124.281 1.00 92.79  ? 8   SER F CB  1 
ATOM   13700 O  OG  . SER F 3 7   ? 122.694 178.217 124.699 1.00 90.57  ? 8   SER F OG  1 
ATOM   13701 N  N   . GLY F 3 8   ? 125.208 181.265 122.403 1.00 92.20  ? 9   GLY F N   1 
ATOM   13702 C  CA  . GLY F 3 8   ? 126.449 181.881 121.973 1.00 87.79  ? 9   GLY F CA  1 
ATOM   13703 C  C   . GLY F 3 8   ? 126.265 183.261 121.376 1.00 86.97  ? 9   GLY F C   1 
ATOM   13704 O  O   . GLY F 3 8   ? 126.959 183.638 120.432 1.00 88.65  ? 9   GLY F O   1 
ATOM   13705 N  N   . LEU F 3 405 ? 135.112 183.016 121.711 1.00 95.56  ? 406 LEU F N   1 
ATOM   13706 C  CA  . LEU F 3 405 ? 133.759 182.725 121.253 1.00 101.08 ? 406 LEU F CA  1 
ATOM   13707 C  C   . LEU F 3 405 ? 133.477 181.231 121.340 1.00 97.16  ? 406 LEU F C   1 
ATOM   13708 O  O   . LEU F 3 405 ? 134.133 180.432 120.679 1.00 97.12  ? 406 LEU F O   1 
ATOM   13709 C  CB  . LEU F 3 405 ? 133.562 183.221 119.821 1.00 102.10 ? 406 LEU F CB  1 
ATOM   13710 C  CG  . LEU F 3 405 ? 134.065 184.642 119.552 1.00 110.50 ? 406 LEU F CG  1 
ATOM   13711 C  CD1 . LEU F 3 405 ? 133.917 185.006 118.090 1.00 109.90 ? 406 LEU F CD1 1 
ATOM   13712 C  CD2 . LEU F 3 405 ? 133.344 185.652 120.429 1.00 111.33 ? 406 LEU F CD2 1 
ATOM   13713 N  N   . ARG F 3 406 ? 132.501 180.857 122.162 1.00 94.54  ? 407 ARG F N   1 
ATOM   13714 C  CA  . ARG F 3 406 ? 132.143 179.461 122.374 1.00 91.91  ? 407 ARG F CA  1 
ATOM   13715 C  C   . ARG F 3 406 ? 130.657 179.268 122.112 1.00 92.52  ? 407 ARG F C   1 
ATOM   13716 O  O   . ARG F 3 406 ? 129.827 179.996 122.662 1.00 92.13  ? 407 ARG F O   1 
ATOM   13717 C  CB  . ARG F 3 406 ? 132.490 179.014 123.795 1.00 88.03  ? 407 ARG F CB  1 
ATOM   13718 C  CG  . ARG F 3 406 ? 132.155 177.565 124.083 1.00 88.70  ? 407 ARG F CG  1 
ATOM   13719 C  CD  . ARG F 3 406 ? 132.723 177.118 125.415 1.00 89.62  ? 407 ARG F CD  1 
ATOM   13720 N  NE  . ARG F 3 406 ? 132.688 175.668 125.555 1.00 94.50  ? 407 ARG F NE  1 
ATOM   13721 C  CZ  . ARG F 3 406 ? 133.276 174.992 126.532 1.00 94.62  ? 407 ARG F CZ  1 
ATOM   13722 N  NH1 . ARG F 3 406 ? 133.951 175.606 127.488 1.00 91.55  ? 407 ARG F NH1 1 
ATOM   13723 N  NH2 . ARG F 3 406 ? 133.187 173.665 126.547 1.00 96.24  ? 407 ARG F NH2 1 
ATOM   13724 N  N   . LEU F 3 407 ? 130.329 178.282 121.283 1.00 90.89  ? 408 LEU F N   1 
ATOM   13725 C  CA  . LEU F 3 407 ? 128.950 177.954 120.954 1.00 88.07  ? 408 LEU F CA  1 
ATOM   13726 C  C   . LEU F 3 407 ? 128.525 176.685 121.677 1.00 87.71  ? 408 LEU F C   1 
ATOM   13727 O  O   . LEU F 3 407 ? 129.293 175.724 121.768 1.00 84.52  ? 408 LEU F O   1 
ATOM   13728 C  CB  . LEU F 3 407 ? 128.775 177.765 119.450 1.00 85.49  ? 408 LEU F CB  1 
ATOM   13729 C  CG  . LEU F 3 407 ? 128.729 179.018 118.589 1.00 87.19  ? 408 LEU F CG  1 
ATOM   13730 C  CD1 . LEU F 3 407 ? 128.484 178.629 117.150 1.00 86.99  ? 408 LEU F CD1 1 
ATOM   13731 C  CD2 . LEU F 3 407 ? 127.642 179.941 119.086 1.00 91.97  ? 408 LEU F CD2 1 
ATOM   13732 N  N   . SER F 3 408 ? 127.293 176.686 122.177 1.00 89.43  ? 409 SER F N   1 
ATOM   13733 C  CA  . SER F 3 408 ? 126.721 175.554 122.887 1.00 89.27  ? 409 SER F CA  1 
ATOM   13734 C  C   . SER F 3 408 ? 125.483 175.061 122.155 1.00 89.36  ? 409 SER F C   1 
ATOM   13735 O  O   . SER F 3 408 ? 124.650 175.860 121.717 1.00 89.20  ? 409 SER F O   1 
ATOM   13736 C  CB  . SER F 3 408 ? 126.351 175.926 124.324 1.00 92.97  ? 409 SER F CB  1 
ATOM   13737 O  OG  . SER F 3 408 ? 127.493 176.306 125.065 1.00 98.93  ? 409 SER F OG  1 
ATOM   13738 N  N   . CYS F 3 409 ? 125.372 173.743 122.026 1.00 85.17  ? 410 CYS F N   1 
ATOM   13739 C  CA  . CYS F 3 409 ? 124.218 173.097 121.415 1.00 83.79  ? 410 CYS F CA  1 
ATOM   13740 C  C   . CYS F 3 409 ? 123.730 172.032 122.382 1.00 88.17  ? 410 CYS F C   1 
ATOM   13741 O  O   . CYS F 3 409 ? 124.406 171.021 122.588 1.00 89.85  ? 410 CYS F O   1 
ATOM   13742 C  CB  . CYS F 3 409 ? 124.582 172.491 120.061 1.00 89.10  ? 410 CYS F CB  1 
ATOM   13743 S  SG  . CYS F 3 409 ? 123.274 171.559 119.249 1.00 104.62 ? 410 CYS F SG  1 
ATOM   13744 N  N   . ALA F 3 410 ? 122.573 172.267 122.988 1.00 91.44  ? 411 ALA F N   1 
ATOM   13745 C  CA  . ALA F 3 410 ? 122.001 171.353 123.969 1.00 88.70  ? 411 ALA F CA  1 
ATOM   13746 C  C   . ALA F 3 410 ? 120.937 170.506 123.289 1.00 88.10  ? 411 ALA F C   1 
ATOM   13747 O  O   . ALA F 3 410 ? 119.954 171.042 122.770 1.00 88.21  ? 411 ALA F O   1 
ATOM   13748 C  CB  . ALA F 3 410 ? 121.411 172.119 125.151 1.00 87.63  ? 411 ALA F CB  1 
ATOM   13749 N  N   . ALA F 3 411 ? 121.139 169.194 123.286 1.00 86.54  ? 412 ALA F N   1 
ATOM   13750 C  CA  . ALA F 3 411 ? 120.244 168.260 122.620 1.00 84.92  ? 412 ALA F CA  1 
ATOM   13751 C  C   . ALA F 3 411 ? 119.559 167.390 123.661 1.00 88.26  ? 412 ALA F C   1 
ATOM   13752 O  O   . ALA F 3 411 ? 120.226 166.766 124.490 1.00 90.37  ? 412 ALA F O   1 
ATOM   13753 C  CB  . ALA F 3 411 ? 121.005 167.390 121.621 1.00 77.59  ? 412 ALA F CB  1 
ATOM   13754 N  N   . SER F 3 412 ? 118.233 167.346 123.611 1.00 88.60  ? 413 SER F N   1 
ATOM   13755 C  CA  . SER F 3 412 ? 117.450 166.566 124.553 1.00 88.86  ? 413 SER F CA  1 
ATOM   13756 C  C   . SER F 3 412 ? 116.504 165.649 123.794 1.00 89.56  ? 413 SER F C   1 
ATOM   13757 O  O   . SER F 3 412 ? 116.092 165.949 122.673 1.00 89.64  ? 413 SER F O   1 
ATOM   13758 C  CB  . SER F 3 412 ? 116.656 167.470 125.503 1.00 87.50  ? 413 SER F CB  1 
ATOM   13759 O  OG  . SER F 3 412 ? 115.718 168.260 124.794 1.00 92.35  ? 413 SER F OG  1 
ATOM   13760 N  N   . GLY F 3 413 ? 116.174 164.513 124.413 1.00 87.95  ? 414 GLY F N   1 
ATOM   13761 C  CA  . GLY F 3 413 ? 115.242 163.558 123.844 1.00 85.95  ? 414 GLY F CA  1 
ATOM   13762 C  C   . GLY F 3 413 ? 115.924 162.232 123.536 1.00 81.38  ? 414 GLY F C   1 
ATOM   13763 O  O   . GLY F 3 413 ? 116.743 161.741 124.320 1.00 82.90  ? 414 GLY F O   1 
ATOM   13764 N  N   . HIS F 3 414 ? 115.573 161.657 122.385 1.00 81.98  ? 415 HIS F N   1 
ATOM   13765 C  CA  . HIS F 3 414 ? 116.103 160.360 121.961 1.00 78.25  ? 415 HIS F CA  1 
ATOM   13766 C  C   . HIS F 3 414 ? 117.492 160.542 121.349 1.00 66.96  ? 415 HIS F C   1 
ATOM   13767 O  O   . HIS F 3 414 ? 117.723 160.319 120.160 1.00 63.50  ? 415 HIS F O   1 
ATOM   13768 C  CB  . HIS F 3 414 ? 115.160 159.697 120.967 1.00 78.97  ? 415 HIS F CB  1 
ATOM   13769 C  CG  . HIS F 3 414 ? 113.788 159.432 121.505 1.00 91.05  ? 415 HIS F CG  1 
ATOM   13770 N  ND1 . HIS F 3 414 ? 113.391 158.190 121.949 1.00 95.72  ? 415 HIS F ND1 1 
ATOM   13771 C  CD2 . HIS F 3 414 ? 112.716 160.245 121.654 1.00 92.66  ? 415 HIS F CD2 1 
ATOM   13772 C  CE1 . HIS F 3 414 ? 112.136 158.251 122.357 1.00 92.86  ? 415 HIS F CE1 1 
ATOM   13773 N  NE2 . HIS F 3 414 ? 111.703 159.487 122.189 1.00 92.18  ? 415 HIS F NE2 1 
ATOM   13774 N  N   . THR F 3 415 ? 118.440 160.944 122.193 1.00 64.39  ? 416 THR F N   1 
ATOM   13775 C  CA  . THR F 3 415 ? 119.795 161.166 121.709 1.00 61.57  ? 416 THR F CA  1 
ATOM   13776 C  C   . THR F 3 415 ? 120.584 159.876 121.546 1.00 55.60  ? 416 THR F C   1 
ATOM   13777 O  O   . THR F 3 415 ? 121.722 159.924 121.069 1.00 54.18  ? 416 THR F O   1 
ATOM   13778 C  CB  . THR F 3 415 ? 120.559 162.111 122.639 1.00 65.49  ? 416 THR F CB  1 
ATOM   13779 O  OG1 . THR F 3 415 ? 120.608 161.556 123.957 1.00 71.69  ? 416 THR F OG1 1 
ATOM   13780 C  CG2 . THR F 3 415 ? 119.885 163.466 122.688 1.00 73.47  ? 416 THR F CG2 1 
ATOM   13781 N  N   . PHE F 3 416 ? 120.031 158.736 121.955 1.00 54.53  ? 417 PHE F N   1 
ATOM   13782 C  CA  . PHE F 3 416 ? 120.707 157.469 121.710 1.00 49.96  ? 417 PHE F CA  1 
ATOM   13783 C  C   . PHE F 3 416 ? 120.545 157.013 120.269 1.00 50.28  ? 417 PHE F C   1 
ATOM   13784 O  O   . PHE F 3 416 ? 121.439 156.353 119.728 1.00 50.48  ? 417 PHE F O   1 
ATOM   13785 C  CB  . PHE F 3 416 ? 120.192 156.391 122.664 1.00 47.18  ? 417 PHE F CB  1 
ATOM   13786 C  CG  . PHE F 3 416 ? 120.902 155.077 122.525 1.00 46.77  ? 417 PHE F CG  1 
ATOM   13787 C  CD1 . PHE F 3 416 ? 122.108 154.861 123.156 1.00 45.90  ? 417 PHE F CD1 1 
ATOM   13788 C  CD2 . PHE F 3 416 ? 120.371 154.064 121.752 1.00 45.45  ? 417 PHE F CD2 1 
ATOM   13789 C  CE1 . PHE F 3 416 ? 122.767 153.657 123.025 1.00 47.88  ? 417 PHE F CE1 1 
ATOM   13790 C  CE2 . PHE F 3 416 ? 121.030 152.860 121.618 1.00 44.23  ? 417 PHE F CE2 1 
ATOM   13791 C  CZ  . PHE F 3 416 ? 122.226 152.657 122.256 1.00 46.61  ? 417 PHE F CZ  1 
ATOM   13792 N  N   . ASN F 3 417 ? 119.420 157.337 119.636 1.00 51.83  ? 418 ASN F N   1 
ATOM   13793 C  CA  . ASN F 3 417 ? 119.229 156.970 118.241 1.00 49.46  ? 418 ASN F CA  1 
ATOM   13794 C  C   . ASN F 3 417 ? 120.064 157.825 117.304 1.00 44.20  ? 418 ASN F C   1 
ATOM   13795 O  O   . ASN F 3 417 ? 120.266 157.441 116.149 1.00 43.60  ? 418 ASN F O   1 
ATOM   13796 C  CB  . ASN F 3 417 ? 117.755 157.088 117.865 1.00 53.29  ? 418 ASN F CB  1 
ATOM   13797 C  CG  . ASN F 3 417 ? 116.861 156.290 118.778 1.00 57.52  ? 418 ASN F CG  1 
ATOM   13798 O  OD1 . ASN F 3 417 ? 117.329 155.663 119.724 1.00 61.36  ? 418 ASN F OD1 1 
ATOM   13799 N  ND2 . ASN F 3 417 ? 115.564 156.320 118.510 1.00 59.65  ? 418 ASN F ND2 1 
ATOM   13800 N  N   . TYR F 3 418 ? 120.561 158.962 117.774 1.00 41.85  ? 419 TYR F N   1 
ATOM   13801 C  CA  . TYR F 3 418 ? 121.266 159.929 116.940 1.00 39.98  ? 419 TYR F CA  1 
ATOM   13802 C  C   . TYR F 3 418 ? 122.616 160.183 117.589 1.00 41.60  ? 419 TYR F C   1 
ATOM   13803 O  O   . TYR F 3 418 ? 122.845 161.240 118.189 1.00 43.64  ? 419 TYR F O   1 
ATOM   13804 C  CB  . TYR F 3 418 ? 120.441 161.205 116.777 1.00 40.45  ? 419 TYR F CB  1 
ATOM   13805 C  CG  . TYR F 3 418 ? 119.150 160.965 116.032 1.00 46.23  ? 419 TYR F CG  1 
ATOM   13806 C  CD1 . TYR F 3 418 ? 118.054 160.401 116.664 1.00 49.01  ? 419 TYR F CD1 1 
ATOM   13807 C  CD2 . TYR F 3 418 ? 119.037 161.276 114.690 1.00 47.29  ? 419 TYR F CD2 1 
ATOM   13808 C  CE1 . TYR F 3 418 ? 116.884 160.164 115.983 1.00 52.20  ? 419 TYR F CE1 1 
ATOM   13809 C  CE2 . TYR F 3 418 ? 117.873 161.047 114.004 1.00 48.95  ? 419 TYR F CE2 1 
ATOM   13810 C  CZ  . TYR F 3 418 ? 116.801 160.490 114.653 1.00 55.15  ? 419 TYR F CZ  1 
ATOM   13811 O  OH  . TYR F 3 418 ? 115.637 160.263 113.966 1.00 64.65  ? 419 TYR F OH  1 
ATOM   13812 N  N   . PRO F 3 419 ? 123.550 159.242 117.453 1.00 39.07  ? 420 PRO F N   1 
ATOM   13813 C  CA  . PRO F 3 419 ? 124.775 159.264 118.253 1.00 37.98  ? 420 PRO F CA  1 
ATOM   13814 C  C   . PRO F 3 419 ? 125.822 160.269 117.805 1.00 42.12  ? 420 PRO F C   1 
ATOM   13815 O  O   . PRO F 3 419 ? 126.923 160.261 118.360 1.00 46.40  ? 420 PRO F O   1 
ATOM   13816 C  CB  . PRO F 3 419 ? 125.299 157.834 118.073 1.00 32.68  ? 420 PRO F CB  1 
ATOM   13817 C  CG  . PRO F 3 419 ? 124.859 157.470 116.721 1.00 33.90  ? 420 PRO F CG  1 
ATOM   13818 C  CD  . PRO F 3 419 ? 123.508 158.079 116.553 1.00 36.34  ? 420 PRO F CD  1 
ATOM   13819 N  N   . ILE F 3 420 ? 125.541 161.120 116.826 1.00 43.09  ? 421 ILE F N   1 
ATOM   13820 C  CA  . ILE F 3 420 ? 126.529 162.055 116.308 1.00 41.74  ? 421 ILE F CA  1 
ATOM   13821 C  C   . ILE F 3 420 ? 125.902 163.433 116.183 1.00 41.98  ? 421 ILE F C   1 
ATOM   13822 O  O   . ILE F 3 420 ? 124.805 163.577 115.632 1.00 42.55  ? 421 ILE F O   1 
ATOM   13823 C  CB  . ILE F 3 420 ? 127.093 161.590 114.955 1.00 38.98  ? 421 ILE F CB  1 
ATOM   13824 C  CG1 . ILE F 3 420 ? 127.988 160.372 115.155 1.00 37.33  ? 421 ILE F CG1 1 
ATOM   13825 C  CG2 . ILE F 3 420 ? 127.855 162.709 114.283 1.00 39.28  ? 421 ILE F CG2 1 
ATOM   13826 C  CD1 . ILE F 3 420 ? 128.652 159.911 113.907 1.00 35.60  ? 421 ILE F CD1 1 
ATOM   13827 N  N   . MET F 3 421 ? 126.598 164.441 116.694 1.00 44.25  ? 422 MET F N   1 
ATOM   13828 C  CA  . MET F 3 421 ? 126.240 165.836 116.505 1.00 46.16  ? 422 MET F CA  1 
ATOM   13829 C  C   . MET F 3 421 ? 127.273 166.495 115.606 1.00 46.77  ? 422 MET F C   1 
ATOM   13830 O  O   . MET F 3 421 ? 128.476 166.288 115.775 1.00 51.06  ? 422 MET F O   1 
ATOM   13831 C  CB  . MET F 3 421 ? 126.166 166.582 117.837 1.00 51.35  ? 422 MET F CB  1 
ATOM   13832 C  CG  . MET F 3 421 ? 125.231 165.970 118.854 1.00 59.06  ? 422 MET F CG  1 
ATOM   13833 S  SD  . MET F 3 421 ? 123.523 165.953 118.309 1.00 67.74  ? 422 MET F SD  1 
ATOM   13834 C  CE  . MET F 3 421 ? 123.258 167.698 118.065 1.00 56.03  ? 422 MET F CE  1 
ATOM   13835 N  N   . GLY F 3 422 ? 126.799 167.279 114.643 1.00 43.60  ? 423 GLY F N   1 
ATOM   13836 C  CA  . GLY F 3 422 ? 127.677 167.969 113.732 1.00 44.72  ? 423 GLY F CA  1 
ATOM   13837 C  C   . GLY F 3 422 ? 127.360 169.450 113.700 1.00 49.06  ? 423 GLY F C   1 
ATOM   13838 O  O   . GLY F 3 422 ? 126.271 169.888 114.070 1.00 56.05  ? 423 GLY F O   1 
ATOM   13839 N  N   . TRP F 3 423 ? 128.343 170.216 113.246 1.00 47.58  ? 424 TRP F N   1 
ATOM   13840 C  CA  . TRP F 3 423 ? 128.242 171.661 113.143 1.00 51.03  ? 424 TRP F CA  1 
ATOM   13841 C  C   . TRP F 3 423 ? 128.356 172.077 111.687 1.00 52.94  ? 424 TRP F C   1 
ATOM   13842 O  O   . TRP F 3 423 ? 129.164 171.529 110.936 1.00 56.18  ? 424 TRP F O   1 
ATOM   13843 C  CB  . TRP F 3 423 ? 129.326 172.346 113.973 1.00 54.49  ? 424 TRP F CB  1 
ATOM   13844 C  CG  . TRP F 3 423 ? 129.069 172.277 115.439 1.00 58.72  ? 424 TRP F CG  1 
ATOM   13845 C  CD1 . TRP F 3 423 ? 129.508 171.323 116.306 1.00 59.52  ? 424 TRP F CD1 1 
ATOM   13846 C  CD2 . TRP F 3 423 ? 128.302 173.199 116.212 1.00 62.80  ? 424 TRP F CD2 1 
ATOM   13847 N  NE1 . TRP F 3 423 ? 129.062 171.596 117.573 1.00 61.37  ? 424 TRP F NE1 1 
ATOM   13848 C  CE2 . TRP F 3 423 ? 128.319 172.744 117.541 1.00 62.99  ? 424 TRP F CE2 1 
ATOM   13849 C  CE3 . TRP F 3 423 ? 127.601 174.367 115.908 1.00 68.07  ? 424 TRP F CE3 1 
ATOM   13850 C  CZ2 . TRP F 3 423 ? 127.667 173.416 118.562 1.00 72.96  ? 424 TRP F CZ2 1 
ATOM   13851 C  CZ3 . TRP F 3 423 ? 126.952 175.032 116.924 1.00 72.11  ? 424 TRP F CZ3 1 
ATOM   13852 C  CH2 . TRP F 3 423 ? 126.989 174.556 118.235 1.00 75.83  ? 424 TRP F CH2 1 
ATOM   13853 N  N   . PHE F 3 424 ? 127.533 173.036 111.288 1.00 56.08  ? 425 PHE F N   1 
ATOM   13854 C  CA  . PHE F 3 424 ? 127.535 173.539 109.927 1.00 57.40  ? 425 PHE F CA  1 
ATOM   13855 C  C   . PHE F 3 424 ? 127.488 175.056 109.968 1.00 67.82  ? 425 PHE F C   1 
ATOM   13856 O  O   . PHE F 3 424 ? 127.028 175.653 110.939 1.00 77.46  ? 425 PHE F O   1 
ATOM   13857 C  CB  . PHE F 3 424 ? 126.348 172.993 109.126 1.00 56.72  ? 425 PHE F CB  1 
ATOM   13858 C  CG  . PHE F 3 424 ? 126.407 171.512 108.891 1.00 50.67  ? 425 PHE F CG  1 
ATOM   13859 C  CD1 . PHE F 3 424 ? 126.059 170.621 109.886 1.00 48.58  ? 425 PHE F CD1 1 
ATOM   13860 C  CD2 . PHE F 3 424 ? 126.799 171.011 107.671 1.00 48.47  ? 425 PHE F CD2 1 
ATOM   13861 C  CE1 . PHE F 3 424 ? 126.118 169.269 109.670 1.00 44.89  ? 425 PHE F CE1 1 
ATOM   13862 C  CE2 . PHE F 3 424 ? 126.857 169.657 107.457 1.00 45.64  ? 425 PHE F CE2 1 
ATOM   13863 C  CZ  . PHE F 3 424 ? 126.513 168.788 108.458 1.00 42.49  ? 425 PHE F CZ  1 
ATOM   13864 N  N   . ARG F 3 425 ? 127.982 175.682 108.909 1.00 71.66  ? 426 ARG F N   1 
ATOM   13865 C  CA  . ARG F 3 425 ? 127.894 177.129 108.781 1.00 76.48  ? 426 ARG F CA  1 
ATOM   13866 C  C   . ARG F 3 425 ? 127.445 177.481 107.374 1.00 82.75  ? 426 ARG F C   1 
ATOM   13867 O  O   . ARG F 3 425 ? 127.858 176.845 106.405 1.00 85.10  ? 426 ARG F O   1 
ATOM   13868 C  CB  . ARG F 3 425 ? 129.227 177.809 109.112 1.00 74.02  ? 426 ARG F CB  1 
ATOM   13869 C  CG  . ARG F 3 425 ? 130.353 177.547 108.138 1.00 74.93  ? 426 ARG F CG  1 
ATOM   13870 C  CD  . ARG F 3 425 ? 131.634 178.208 108.614 1.00 76.59  ? 426 ARG F CD  1 
ATOM   13871 N  NE  . ARG F 3 425 ? 132.702 178.110 107.628 1.00 75.64  ? 426 ARG F NE  1 
ATOM   13872 C  CZ  . ARG F 3 425 ? 133.974 178.387 107.876 1.00 81.13  ? 426 ARG F CZ  1 
ATOM   13873 N  NH1 . ARG F 3 425 ? 134.377 178.762 109.078 1.00 83.61  ? 426 ARG F NH1 1 
ATOM   13874 N  NH2 . ARG F 3 425 ? 134.865 178.276 106.897 1.00 84.61  ? 426 ARG F NH2 1 
ATOM   13875 N  N   . GLN F 3 426 ? 126.576 178.479 107.263 1.00 88.03  ? 427 GLN F N   1 
ATOM   13876 C  CA  . GLN F 3 426 ? 126.058 178.913 105.973 1.00 92.00  ? 427 GLN F CA  1 
ATOM   13877 C  C   . GLN F 3 426 ? 126.463 180.359 105.742 1.00 99.31  ? 427 GLN F C   1 
ATOM   13878 O  O   . GLN F 3 426 ? 126.189 181.226 106.578 1.00 97.93  ? 427 GLN F O   1 
ATOM   13879 C  CB  . GLN F 3 426 ? 124.540 178.755 105.906 1.00 90.22  ? 427 GLN F CB  1 
ATOM   13880 C  CG  . GLN F 3 426 ? 123.962 179.033 104.533 1.00 95.75  ? 427 GLN F CG  1 
ATOM   13881 C  CD  . GLN F 3 426 ? 122.544 178.529 104.381 1.00 96.15  ? 427 GLN F CD  1 
ATOM   13882 O  OE1 . GLN F 3 426 ? 121.917 178.104 105.350 1.00 94.97  ? 427 GLN F OE1 1 
ATOM   13883 N  NE2 . GLN F 3 426 ? 122.031 178.565 103.159 1.00 95.41  ? 427 GLN F NE2 1 
ATOM   13884 N  N   . ALA F 3 427 ? 127.122 180.611 104.615 1.00 106.93 ? 428 ALA F N   1 
ATOM   13885 C  CA  . ALA F 3 427 ? 127.482 181.964 104.239 1.00 109.32 ? 428 ALA F CA  1 
ATOM   13886 C  C   . ALA F 3 427 ? 126.247 182.714 103.750 1.00 113.63 ? 428 ALA F C   1 
ATOM   13887 O  O   . ALA F 3 427 ? 125.251 182.099 103.361 1.00 111.45 ? 428 ALA F O   1 
ATOM   13888 C  CB  . ALA F 3 427 ? 128.556 181.947 103.155 1.00 108.93 ? 428 ALA F CB  1 
ATOM   13889 N  N   . PRO F 3 428 ? 126.280 184.048 103.771 1.00 117.38 ? 429 PRO F N   1 
ATOM   13890 C  CA  . PRO F 3 428 ? 125.126 184.813 103.272 1.00 118.56 ? 429 PRO F CA  1 
ATOM   13891 C  C   . PRO F 3 428 ? 124.845 184.602 101.795 1.00 118.98 ? 429 PRO F C   1 
ATOM   13892 O  O   . PRO F 3 428 ? 123.725 184.882 101.351 1.00 116.99 ? 429 PRO F O   1 
ATOM   13893 C  CB  . PRO F 3 428 ? 125.513 186.267 103.570 1.00 114.44 ? 429 PRO F CB  1 
ATOM   13894 C  CG  . PRO F 3 428 ? 126.999 186.249 103.680 1.00 112.77 ? 429 PRO F CG  1 
ATOM   13895 C  CD  . PRO F 3 428 ? 127.332 184.933 104.299 1.00 111.22 ? 429 PRO F CD  1 
ATOM   13896 N  N   . GLY F 3 429 ? 125.816 184.124 101.020 1.00 117.67 ? 430 GLY F N   1 
ATOM   13897 C  CA  . GLY F 3 429 ? 125.596 183.877 99.610  1.00 114.84 ? 430 GLY F CA  1 
ATOM   13898 C  C   . GLY F 3 429 ? 126.013 182.494 99.152  1.00 113.79 ? 430 GLY F C   1 
ATOM   13899 O  O   . GLY F 3 429 ? 126.220 182.268 97.956  1.00 112.26 ? 430 GLY F O   1 
ATOM   13900 N  N   . LYS F 3 430 ? 126.141 181.557 100.090 1.00 114.30 ? 431 LYS F N   1 
ATOM   13901 C  CA  . LYS F 3 430 ? 126.570 180.204 99.756  1.00 112.47 ? 431 LYS F CA  1 
ATOM   13902 C  C   . LYS F 3 430 ? 125.668 179.170 100.419 1.00 110.68 ? 431 LYS F C   1 
ATOM   13903 O  O   . LYS F 3 430 ? 124.638 179.522 101.001 1.00 110.92 ? 431 LYS F O   1 
ATOM   13904 C  CB  . LYS F 3 430 ? 128.028 179.993 100.170 1.00 109.81 ? 431 LYS F CB  1 
ATOM   13905 C  CG  . LYS F 3 430 ? 128.998 180.975 99.526  1.00 109.74 ? 431 LYS F CG  1 
ATOM   13906 C  CD  . LYS F 3 430 ? 130.380 180.901 100.145 1.00 106.57 ? 431 LYS F CD  1 
ATOM   13907 C  CE  . LYS F 3 430 ? 131.348 181.823 99.423  1.00 98.91  ? 431 LYS F CE  1 
ATOM   13908 N  NZ  . LYS F 3 430 ? 132.702 181.808 100.044 1.00 92.92  ? 431 LYS F NZ  1 
ATOM   13909 N  N   . GLU F 3 431 ? 126.039 177.898 100.332 1.00 106.93 ? 432 GLU F N   1 
ATOM   13910 C  CA  . GLU F 3 431 ? 125.261 176.818 100.918 1.00 102.91 ? 432 GLU F CA  1 
ATOM   13911 C  C   . GLU F 3 431 ? 125.910 176.332 102.212 1.00 99.25  ? 432 GLU F C   1 
ATOM   13912 O  O   . GLU F 3 431 ? 127.009 176.750 102.581 1.00 98.65  ? 432 GLU F O   1 
ATOM   13913 C  CB  . GLU F 3 431 ? 125.108 175.667 99.921  1.00 106.50 ? 432 GLU F CB  1 
ATOM   13914 C  CG  . GLU F 3 431 ? 123.822 174.875 100.102 1.00 113.22 ? 432 GLU F CG  1 
ATOM   13915 C  CD  . GLU F 3 431 ? 123.668 173.762 99.088  1.00 126.47 ? 432 GLU F CD  1 
ATOM   13916 O  OE1 . GLU F 3 431 ? 124.589 173.568 98.267  1.00 126.11 ? 432 GLU F OE1 1 
ATOM   13917 O  OE2 . GLU F 3 431 ? 122.620 173.084 99.113  1.00 131.59 ? 432 GLU F OE2 1 
ATOM   13918 N  N   . ARG F 3 432 ? 125.203 175.445 102.911 1.00 95.10  ? 433 ARG F N   1 
ATOM   13919 C  CA  . ARG F 3 432 ? 125.687 174.942 104.190 1.00 86.23  ? 433 ARG F CA  1 
ATOM   13920 C  C   . ARG F 3 432 ? 126.981 174.161 104.011 1.00 80.94  ? 433 ARG F C   1 
ATOM   13921 O  O   . ARG F 3 432 ? 127.125 173.364 103.081 1.00 83.09  ? 433 ARG F O   1 
ATOM   13922 C  CB  . ARG F 3 432 ? 124.632 174.061 104.853 1.00 78.18  ? 433 ARG F CB  1 
ATOM   13923 C  CG  . ARG F 3 432 ? 123.474 174.829 105.451 1.00 80.28  ? 433 ARG F CG  1 
ATOM   13924 C  CD  . ARG F 3 432 ? 122.467 173.895 106.091 1.00 73.39  ? 433 ARG F CD  1 
ATOM   13925 N  NE  . ARG F 3 432 ? 121.365 174.626 106.704 1.00 75.97  ? 433 ARG F NE  1 
ATOM   13926 C  CZ  . ARG F 3 432 ? 120.269 174.061 107.188 1.00 74.28  ? 433 ARG F CZ  1 
ATOM   13927 N  NH1 . ARG F 3 432 ? 120.087 172.753 107.137 1.00 71.89  ? 433 ARG F NH1 1 
ATOM   13928 N  NH2 . ARG F 3 432 ? 119.328 174.829 107.730 1.00 75.48  ? 433 ARG F NH2 1 
ATOM   13929 N  N   . GLU F 3 433 ? 127.922 174.388 104.920 1.00 73.08  ? 434 GLU F N   1 
ATOM   13930 C  CA  . GLU F 3 433 ? 129.244 173.794 104.858 1.00 67.17  ? 434 GLU F CA  1 
ATOM   13931 C  C   . GLU F 3 433 ? 129.533 173.102 106.178 1.00 65.68  ? 434 GLU F C   1 
ATOM   13932 O  O   . GLU F 3 433 ? 129.325 173.684 107.246 1.00 68.58  ? 434 GLU F O   1 
ATOM   13933 C  CB  . GLU F 3 433 ? 130.300 174.862 104.568 1.00 69.20  ? 434 GLU F CB  1 
ATOM   13934 C  CG  . GLU F 3 433 ? 131.727 174.432 104.826 1.00 76.08  ? 434 GLU F CG  1 
ATOM   13935 C  CD  . GLU F 3 433 ? 132.713 175.569 104.647 1.00 86.91  ? 434 GLU F CD  1 
ATOM   13936 O  OE1 . GLU F 3 433 ? 132.290 176.664 104.217 1.00 88.51  ? 434 GLU F OE1 1 
ATOM   13937 O  OE2 . GLU F 3 433 ? 133.910 175.367 104.939 1.00 86.18  ? 434 GLU F OE2 1 
ATOM   13938 N  N   . PHE F 3 434 ? 129.997 171.860 106.092 1.00 60.09  ? 435 PHE F N   1 
ATOM   13939 C  CA  . PHE F 3 434 ? 130.358 171.085 107.269 1.00 53.63  ? 435 PHE F CA  1 
ATOM   13940 C  C   . PHE F 3 434 ? 131.566 171.704 107.957 1.00 52.74  ? 435 PHE F C   1 
ATOM   13941 O  O   . PHE F 3 434 ? 132.510 172.147 107.300 1.00 55.16  ? 435 PHE F O   1 
ATOM   13942 C  CB  . PHE F 3 434 ? 130.649 169.647 106.843 1.00 51.03  ? 435 PHE F CB  1 
ATOM   13943 C  CG  . PHE F 3 434 ? 131.142 168.757 107.940 1.00 47.98  ? 435 PHE F CG  1 
ATOM   13944 C  CD1 . PHE F 3 434 ? 130.272 168.245 108.880 1.00 45.45  ? 435 PHE F CD1 1 
ATOM   13945 C  CD2 . PHE F 3 434 ? 132.469 168.387 107.999 1.00 47.83  ? 435 PHE F CD2 1 
ATOM   13946 C  CE1 . PHE F 3 434 ? 130.723 167.408 109.869 1.00 44.35  ? 435 PHE F CE1 1 
ATOM   13947 C  CE2 . PHE F 3 434 ? 132.921 167.550 108.988 1.00 45.06  ? 435 PHE F CE2 1 
ATOM   13948 C  CZ  . PHE F 3 434 ? 132.050 167.064 109.923 1.00 43.65  ? 435 PHE F CZ  1 
ATOM   13949 N  N   . VAL F 3 435 ? 131.537 171.740 109.287 1.00 51.34  ? 436 VAL F N   1 
ATOM   13950 C  CA  . VAL F 3 435 ? 132.609 172.312 110.090 1.00 53.47  ? 436 VAL F CA  1 
ATOM   13951 C  C   . VAL F 3 435 ? 133.290 171.248 110.939 1.00 51.57  ? 436 VAL F C   1 
ATOM   13952 O  O   . VAL F 3 435 ? 134.512 171.110 110.917 1.00 55.66  ? 436 VAL F O   1 
ATOM   13953 C  CB  . VAL F 3 435 ? 132.081 173.464 110.972 1.00 53.37  ? 436 VAL F CB  1 
ATOM   13954 C  CG1 . VAL F 3 435 ? 133.166 173.953 111.893 1.00 58.31  ? 436 VAL F CG1 1 
ATOM   13955 C  CG2 . VAL F 3 435 ? 131.557 174.594 110.116 1.00 56.68  ? 436 VAL F CG2 1 
ATOM   13956 N  N   . GLY F 3 436 ? 132.510 170.488 111.693 1.00 45.90  ? 437 GLY F N   1 
ATOM   13957 C  CA  . GLY F 3 436 ? 133.062 169.440 112.524 1.00 45.65  ? 437 GLY F CA  1 
ATOM   13958 C  C   . GLY F 3 436 ? 131.960 168.578 113.088 1.00 47.57  ? 437 GLY F C   1 
ATOM   13959 O  O   . GLY F 3 436 ? 130.784 168.951 113.072 1.00 50.13  ? 437 GLY F O   1 
ATOM   13960 N  N   . ALA F 3 437 ? 132.360 167.413 113.587 1.00 46.10  ? 438 ALA F N   1 
ATOM   13961 C  CA  . ALA F 3 437 ? 131.401 166.467 114.138 1.00 43.24  ? 438 ALA F CA  1 
ATOM   13962 C  C   . ALA F 3 437 ? 132.053 165.670 115.254 1.00 46.47  ? 438 ALA F C   1 
ATOM   13963 O  O   . ALA F 3 437 ? 133.239 165.344 115.189 1.00 55.21  ? 438 ALA F O   1 
ATOM   13964 C  CB  . ALA F 3 437 ? 130.860 165.523 113.063 1.00 42.20  ? 438 ALA F CB  1 
ATOM   13965 N  N   . ILE F 3 438 ? 131.260 165.346 116.273 1.00 48.19  ? 439 ILE F N   1 
ATOM   13966 C  CA  . ILE F 3 438 ? 131.748 164.646 117.455 1.00 49.96  ? 439 ILE F CA  1 
ATOM   13967 C  C   . ILE F 3 438 ? 130.804 163.503 117.793 1.00 49.86  ? 439 ILE F C   1 
ATOM   13968 O  O   . ILE F 3 438 ? 129.580 163.657 117.749 1.00 50.75  ? 439 ILE F O   1 
ATOM   13969 C  CB  . ILE F 3 438 ? 131.906 165.599 118.658 1.00 52.40  ? 439 ILE F CB  1 
ATOM   13970 C  CG1 . ILE F 3 438 ? 132.405 164.837 119.882 1.00 53.33  ? 439 ILE F CG1 1 
ATOM   13971 C  CG2 . ILE F 3 438 ? 130.604 166.302 118.978 1.00 52.33  ? 439 ILE F CG2 1 
ATOM   13972 C  CD1 . ILE F 3 438 ? 132.667 165.718 121.066 1.00 62.10  ? 439 ILE F CD1 1 
ATOM   13973 N  N   . SER F 3 439 ? 131.378 162.351 118.120 1.00 51.13  ? 440 SER F N   1 
ATOM   13974 C  CA  . SER F 3 439 ? 130.595 161.229 118.611 1.00 50.74  ? 440 SER F CA  1 
ATOM   13975 C  C   . SER F 3 439 ? 130.126 161.493 120.037 1.00 56.96  ? 440 SER F C   1 
ATOM   13976 O  O   . SER F 3 439 ? 130.856 162.059 120.850 1.00 62.33  ? 440 SER F O   1 
ATOM   13977 C  CB  . SER F 3 439 ? 131.431 159.954 118.556 1.00 52.28  ? 440 SER F CB  1 
ATOM   13978 O  OG  . SER F 3 439 ? 130.711 158.851 119.065 1.00 59.66  ? 440 SER F OG  1 
ATOM   13979 N  N   . TRP F 3 440 ? 128.891 161.088 120.339 1.00 59.66  ? 441 TRP F N   1 
ATOM   13980 C  CA  . TRP F 3 440 ? 128.341 161.338 121.670 1.00 60.69  ? 441 TRP F CA  1 
ATOM   13981 C  C   . TRP F 3 440 ? 129.078 160.544 122.740 1.00 61.84  ? 441 TRP F C   1 
ATOM   13982 O  O   . TRP F 3 440 ? 129.301 161.041 123.849 1.00 64.80  ? 441 TRP F O   1 
ATOM   13983 C  CB  . TRP F 3 440 ? 126.853 161.001 121.707 1.00 56.77  ? 441 TRP F CB  1 
ATOM   13984 C  CG  . TRP F 3 440 ? 125.948 162.178 121.553 1.00 56.65  ? 441 TRP F CG  1 
ATOM   13985 C  CD1 . TRP F 3 440 ? 125.015 162.369 120.581 1.00 57.93  ? 441 TRP F CD1 1 
ATOM   13986 C  CD2 . TRP F 3 440 ? 125.881 163.324 122.402 1.00 61.75  ? 441 TRP F CD2 1 
ATOM   13987 N  NE1 . TRP F 3 440 ? 124.370 163.563 120.770 1.00 61.17  ? 441 TRP F NE1 1 
ATOM   13988 C  CE2 . TRP F 3 440 ? 124.886 164.171 121.882 1.00 66.36  ? 441 TRP F CE2 1 
ATOM   13989 C  CE3 . TRP F 3 440 ? 126.565 163.717 123.552 1.00 66.79  ? 441 TRP F CE3 1 
ATOM   13990 C  CZ2 . TRP F 3 440 ? 124.560 165.387 122.471 1.00 70.65  ? 441 TRP F CZ2 1 
ATOM   13991 C  CZ3 . TRP F 3 440 ? 126.242 164.924 124.133 1.00 75.63  ? 441 TRP F CZ3 1 
ATOM   13992 C  CH2 . TRP F 3 440 ? 125.248 165.745 123.593 1.00 73.53  ? 441 TRP F CH2 1 
ATOM   13993 N  N   . SER F 3 441 ? 129.451 159.304 122.433 1.00 59.28  ? 442 SER F N   1 
ATOM   13994 C  CA  . SER F 3 441 ? 129.993 158.386 123.425 1.00 60.53  ? 442 SER F CA  1 
ATOM   13995 C  C   . SER F 3 441 ? 131.513 158.418 123.504 1.00 63.36  ? 442 SER F C   1 
ATOM   13996 O  O   . SER F 3 441 ? 132.071 158.710 124.563 1.00 65.78  ? 442 SER F O   1 
ATOM   13997 C  CB  . SER F 3 441 ? 129.520 156.962 123.118 1.00 60.97  ? 442 SER F CB  1 
ATOM   13998 O  OG  . SER F 3 441 ? 129.913 156.064 124.140 1.00 69.79  ? 442 SER F OG  1 
ATOM   13999 N  N   . GLY F 3 442 ? 132.198 158.122 122.402 1.00 63.17  ? 443 GLY F N   1 
ATOM   14000 C  CA  . GLY F 3 442 ? 133.646 158.018 122.456 1.00 65.91  ? 443 GLY F CA  1 
ATOM   14001 C  C   . GLY F 3 442 ? 134.347 159.361 122.377 1.00 68.71  ? 443 GLY F C   1 
ATOM   14002 O  O   . GLY F 3 442 ? 135.549 159.459 122.638 1.00 72.90  ? 443 GLY F O   1 
ATOM   14003 N  N   . GLY F 3 443 ? 133.620 160.406 122.004 1.00 63.20  ? 444 GLY F N   1 
ATOM   14004 C  CA  . GLY F 3 443 ? 134.220 161.709 121.837 1.00 58.10  ? 444 GLY F CA  1 
ATOM   14005 C  C   . GLY F 3 443 ? 135.096 161.848 120.615 1.00 59.24  ? 444 GLY F C   1 
ATOM   14006 O  O   . GLY F 3 443 ? 135.784 162.866 120.482 1.00 56.28  ? 444 GLY F O   1 
ATOM   14007 N  N   . SER F 3 444 ? 135.098 160.858 119.727 1.00 62.39  ? 445 SER F N   1 
ATOM   14008 C  CA  . SER F 3 444 ? 135.871 160.945 118.497 1.00 60.14  ? 445 SER F CA  1 
ATOM   14009 C  C   . SER F 3 444 ? 135.380 162.112 117.650 1.00 61.42  ? 445 SER F C   1 
ATOM   14010 O  O   . SER F 3 444 ? 134.178 162.362 117.543 1.00 62.51  ? 445 SER F O   1 
ATOM   14011 C  CB  . SER F 3 444 ? 135.761 159.634 117.722 1.00 55.91  ? 445 SER F CB  1 
ATOM   14012 O  OG  . SER F 3 444 ? 136.496 159.686 116.517 1.00 59.42  ? 445 SER F OG  1 
ATOM   14013 N  N   . THR F 3 445 ? 136.319 162.830 117.046 1.00 60.52  ? 446 THR F N   1 
ATOM   14014 C  CA  . THR F 3 445 ? 136.023 164.098 116.401 1.00 59.25  ? 446 THR F CA  1 
ATOM   14015 C  C   . THR F 3 445 ? 136.563 164.114 114.979 1.00 59.96  ? 446 THR F C   1 
ATOM   14016 O  O   . THR F 3 445 ? 137.506 163.399 114.636 1.00 64.28  ? 446 THR F O   1 
ATOM   14017 C  CB  . THR F 3 445 ? 136.616 165.266 117.191 1.00 59.13  ? 446 THR F CB  1 
ATOM   14018 O  OG1 . THR F 3 445 ? 137.981 164.974 117.510 1.00 64.90  ? 446 THR F OG1 1 
ATOM   14019 C  CG2 . THR F 3 445 ? 135.841 165.486 118.472 1.00 57.17  ? 446 THR F CG2 1 
ATOM   14020 N  N   . SER F 3 446 ? 135.935 164.942 114.150 1.00 56.54  ? 447 SER F N   1 
ATOM   14021 C  CA  . SER F 3 446 ? 136.371 165.156 112.779 1.00 54.82  ? 447 SER F CA  1 
ATOM   14022 C  C   . SER F 3 446 ? 136.171 166.620 112.426 1.00 53.54  ? 447 SER F C   1 
ATOM   14023 O  O   . SER F 3 446 ? 135.179 167.227 112.836 1.00 52.94  ? 447 SER F O   1 
ATOM   14024 C  CB  . SER F 3 446 ? 135.600 164.263 111.806 1.00 58.51  ? 447 SER F CB  1 
ATOM   14025 O  OG  . SER F 3 446 ? 136.076 164.429 110.485 1.00 62.76  ? 447 SER F OG  1 
ATOM   14026 N  N   . TYR F 3 447 ? 137.105 167.177 111.658 1.00 53.90  ? 448 TYR F N   1 
ATOM   14027 C  CA  . TYR F 3 447 ? 137.106 168.595 111.329 1.00 54.98  ? 448 TYR F CA  1 
ATOM   14028 C  C   . TYR F 3 447 ? 137.349 168.794 109.842 1.00 57.39  ? 448 TYR F C   1 
ATOM   14029 O  O   . TYR F 3 447 ? 137.927 167.944 109.163 1.00 62.97  ? 448 TYR F O   1 
ATOM   14030 C  CB  . TYR F 3 447 ? 138.179 169.360 112.111 1.00 60.45  ? 448 TYR F CB  1 
ATOM   14031 C  CG  . TYR F 3 447 ? 138.092 169.195 113.604 1.00 61.81  ? 448 TYR F CG  1 
ATOM   14032 C  CD1 . TYR F 3 447 ? 137.268 170.007 114.361 1.00 60.00  ? 448 TYR F CD1 1 
ATOM   14033 C  CD2 . TYR F 3 447 ? 138.841 168.232 114.255 1.00 62.86  ? 448 TYR F CD2 1 
ATOM   14034 C  CE1 . TYR F 3 447 ? 137.186 169.860 115.722 1.00 62.80  ? 448 TYR F CE1 1 
ATOM   14035 C  CE2 . TYR F 3 447 ? 138.764 168.076 115.615 1.00 62.88  ? 448 TYR F CE2 1 
ATOM   14036 C  CZ  . TYR F 3 447 ? 137.935 168.891 116.345 1.00 65.52  ? 448 TYR F CZ  1 
ATOM   14037 O  OH  . TYR F 3 447 ? 137.860 168.737 117.708 1.00 69.93  ? 448 TYR F OH  1 
ATOM   14038 N  N   . ALA F 3 448 ? 136.903 169.942 109.345 1.00 57.82  ? 449 ALA F N   1 
ATOM   14039 C  CA  . ALA F 3 448 ? 137.201 170.348 107.984 1.00 63.60  ? 449 ALA F CA  1 
ATOM   14040 C  C   . ALA F 3 448 ? 138.626 170.881 107.894 1.00 77.98  ? 449 ALA F C   1 
ATOM   14041 O  O   . ALA F 3 448 ? 139.238 171.262 108.894 1.00 85.74  ? 449 ALA F O   1 
ATOM   14042 C  CB  . ALA F 3 448 ? 136.211 171.409 107.512 1.00 60.41  ? 449 ALA F CB  1 
ATOM   14043 N  N   . ASP F 3 449 ? 139.161 170.900 106.672 1.00 79.84  ? 450 ASP F N   1 
ATOM   14044 C  CA  . ASP F 3 449 ? 140.532 171.364 106.485 1.00 82.96  ? 450 ASP F CA  1 
ATOM   14045 C  C   . ASP F 3 449 ? 140.675 172.837 106.843 1.00 86.36  ? 450 ASP F C   1 
ATOM   14046 O  O   . ASP F 3 449 ? 141.672 173.242 107.452 1.00 87.98  ? 450 ASP F O   1 
ATOM   14047 C  CB  . ASP F 3 449 ? 140.982 171.117 105.047 1.00 84.97  ? 450 ASP F CB  1 
ATOM   14048 C  CG  . ASP F 3 449 ? 141.353 169.673 104.792 1.00 89.88  ? 450 ASP F CG  1 
ATOM   14049 O  OD1 . ASP F 3 449 ? 141.173 168.840 105.704 1.00 90.08  ? 450 ASP F OD1 1 
ATOM   14050 O  OD2 . ASP F 3 449 ? 141.836 169.374 103.682 1.00 92.30  ? 450 ASP F OD2 1 
ATOM   14051 N  N   . SER F 3 450 ? 139.690 173.656 106.474 1.00 86.46  ? 451 SER F N   1 
ATOM   14052 C  CA  . SER F 3 450 ? 139.799 175.093 106.688 1.00 89.97  ? 451 SER F CA  1 
ATOM   14053 C  C   . SER F 3 450 ? 139.724 175.479 108.159 1.00 89.49  ? 451 SER F C   1 
ATOM   14054 O  O   . SER F 3 450 ? 140.177 176.568 108.522 1.00 91.64  ? 451 SER F O   1 
ATOM   14055 C  CB  . SER F 3 450 ? 138.707 175.820 105.905 1.00 90.83  ? 451 SER F CB  1 
ATOM   14056 O  OG  . SER F 3 450 ? 137.428 175.311 106.232 1.00 88.31  ? 451 SER F OG  1 
ATOM   14057 N  N   . VAL F 3 451 ? 139.167 174.623 109.012 1.00 85.92  ? 452 VAL F N   1 
ATOM   14058 C  CA  . VAL F 3 451 ? 139.003 174.929 110.427 1.00 82.75  ? 452 VAL F CA  1 
ATOM   14059 C  C   . VAL F 3 451 ? 139.834 174.028 111.316 1.00 84.22  ? 452 VAL F C   1 
ATOM   14060 O  O   . VAL F 3 451 ? 139.801 174.187 112.543 1.00 84.95  ? 452 VAL F O   1 
ATOM   14061 C  CB  . VAL F 3 451 ? 137.523 174.859 110.840 1.00 82.02  ? 452 VAL F CB  1 
ATOM   14062 C  CG1 . VAL F 3 451 ? 136.680 175.713 109.912 1.00 82.79  ? 452 VAL F CG1 1 
ATOM   14063 C  CG2 . VAL F 3 451 ? 137.046 173.425 110.827 1.00 78.27  ? 452 VAL F CG2 1 
ATOM   14064 N  N   . LYS F 3 452 ? 140.579 173.089 110.742 1.00 85.74  ? 453 LYS F N   1 
ATOM   14065 C  CA  . LYS F 3 452 ? 141.359 172.155 111.540 1.00 87.56  ? 453 LYS F CA  1 
ATOM   14066 C  C   . LYS F 3 452 ? 142.435 172.895 112.322 1.00 95.06  ? 453 LYS F C   1 
ATOM   14067 O  O   . LYS F 3 452 ? 143.016 173.871 111.839 1.00 99.58  ? 453 LYS F O   1 
ATOM   14068 C  CB  . LYS F 3 452 ? 141.993 171.103 110.633 1.00 89.23  ? 453 LYS F CB  1 
ATOM   14069 C  CG  . LYS F 3 452 ? 142.551 169.893 111.354 1.00 89.34  ? 453 LYS F CG  1 
ATOM   14070 C  CD  . LYS F 3 452 ? 143.131 168.909 110.354 1.00 95.57  ? 453 LYS F CD  1 
ATOM   14071 C  CE  . LYS F 3 452 ? 143.611 167.640 111.023 1.00 103.70 ? 453 LYS F CE  1 
ATOM   14072 N  NZ  . LYS F 3 452 ? 144.429 166.815 110.092 1.00 111.59 ? 453 LYS F NZ  1 
ATOM   14073 N  N   . ASP F 3 453 ? 142.685 172.434 113.547 1.00 94.41  ? 454 ASP F N   1 
ATOM   14074 C  CA  . ASP F 3 453 ? 143.660 172.986 114.484 1.00 96.87  ? 454 ASP F CA  1 
ATOM   14075 C  C   . ASP F 3 453 ? 143.310 174.394 114.952 1.00 96.58  ? 454 ASP F C   1 
ATOM   14076 O  O   . ASP F 3 453 ? 144.084 174.984 115.709 1.00 97.38  ? 454 ASP F O   1 
ATOM   14077 C  CB  . ASP F 3 453 ? 145.084 172.997 113.911 1.00 100.75 ? 454 ASP F CB  1 
ATOM   14078 C  CG  . ASP F 3 453 ? 145.581 171.610 113.567 1.00 102.27 ? 454 ASP F CG  1 
ATOM   14079 O  OD1 . ASP F 3 453 ? 145.100 170.640 114.185 1.00 102.79 ? 454 ASP F OD1 1 
ATOM   14080 O  OD2 . ASP F 3 453 ? 146.454 171.489 112.681 1.00 102.22 ? 454 ASP F OD2 1 
ATOM   14081 N  N   . ARG F 3 454 ? 142.175 174.953 114.533 1.00 95.91  ? 455 ARG F N   1 
ATOM   14082 C  CA  . ARG F 3 454 ? 141.699 176.232 115.041 1.00 95.48  ? 455 ARG F CA  1 
ATOM   14083 C  C   . ARG F 3 454 ? 140.474 176.057 115.927 1.00 96.23  ? 455 ARG F C   1 
ATOM   14084 O  O   . ARG F 3 454 ? 140.491 176.458 117.093 1.00 99.52  ? 455 ARG F O   1 
ATOM   14085 C  CB  . ARG F 3 454 ? 141.384 177.185 113.881 1.00 95.28  ? 455 ARG F CB  1 
ATOM   14086 C  CG  . ARG F 3 454 ? 142.571 177.493 112.990 1.00 99.24  ? 455 ARG F CG  1 
ATOM   14087 C  CD  . ARG F 3 454 ? 142.329 178.736 112.148 1.00 100.97 ? 455 ARG F CD  1 
ATOM   14088 N  NE  . ARG F 3 454 ? 141.265 178.559 111.166 1.00 100.53 ? 455 ARG F NE  1 
ATOM   14089 C  CZ  . ARG F 3 454 ? 140.023 178.995 111.317 1.00 98.71  ? 455 ARG F CZ  1 
ATOM   14090 N  NH1 . ARG F 3 454 ? 139.640 179.625 112.415 1.00 98.72  ? 455 ARG F NH1 1 
ATOM   14091 N  NH2 . ARG F 3 454 ? 139.142 178.798 110.341 1.00 96.67  ? 455 ARG F NH2 1 
ATOM   14092 N  N   . PHE F 3 455 ? 139.413 175.447 115.409 1.00 93.37  ? 456 PHE F N   1 
ATOM   14093 C  CA  . PHE F 3 455 ? 138.237 175.137 116.205 1.00 87.98  ? 456 PHE F CA  1 
ATOM   14094 C  C   . PHE F 3 455 ? 138.439 173.821 116.947 1.00 85.55  ? 456 PHE F C   1 
ATOM   14095 O  O   . PHE F 3 455 ? 139.275 172.994 116.581 1.00 85.42  ? 456 PHE F O   1 
ATOM   14096 C  CB  . PHE F 3 455 ? 136.984 175.035 115.332 1.00 85.31  ? 456 PHE F CB  1 
ATOM   14097 C  CG  . PHE F 3 455 ? 136.645 176.292 114.581 1.00 86.08  ? 456 PHE F CG  1 
ATOM   14098 C  CD1 . PHE F 3 455 ? 137.228 177.502 114.906 1.00 89.94  ? 456 PHE F CD1 1 
ATOM   14099 C  CD2 . PHE F 3 455 ? 135.726 176.259 113.552 1.00 84.29  ? 456 PHE F CD2 1 
ATOM   14100 C  CE1 . PHE F 3 455 ? 136.906 178.651 114.206 1.00 92.92  ? 456 PHE F CE1 1 
ATOM   14101 C  CE2 . PHE F 3 455 ? 135.400 177.403 112.854 1.00 85.69  ? 456 PHE F CE2 1 
ATOM   14102 C  CZ  . PHE F 3 455 ? 135.991 178.599 113.181 1.00 89.99  ? 456 PHE F CZ  1 
ATOM   14103 N  N   . THR F 3 456 ? 137.657 173.640 118.007 1.00 85.61  ? 457 THR F N   1 
ATOM   14104 C  CA  . THR F 3 456 ? 137.632 172.384 118.744 1.00 83.35  ? 457 THR F CA  1 
ATOM   14105 C  C   . THR F 3 456 ? 136.192 172.063 119.115 1.00 83.29  ? 457 THR F C   1 
ATOM   14106 O  O   . THR F 3 456 ? 135.360 172.960 119.250 1.00 87.39  ? 457 THR F O   1 
ATOM   14107 C  CB  . THR F 3 456 ? 138.502 172.438 120.007 1.00 86.87  ? 457 THR F CB  1 
ATOM   14108 O  OG1 . THR F 3 456 ? 139.741 173.091 119.707 1.00 94.33  ? 457 THR F OG1 1 
ATOM   14109 C  CG2 . THR F 3 456 ? 138.804 171.035 120.510 1.00 80.08  ? 457 THR F CG2 1 
ATOM   14110 N  N   . ILE F 3 457 ? 135.897 170.776 119.264 1.00 79.76  ? 458 ILE F N   1 
ATOM   14111 C  CA  . ILE F 3 457 ? 134.570 170.318 119.653 1.00 77.63  ? 458 ILE F CA  1 
ATOM   14112 C  C   . ILE F 3 457 ? 134.697 169.428 120.878 1.00 78.07  ? 458 ILE F C   1 
ATOM   14113 O  O   . ILE F 3 457 ? 135.580 168.567 120.946 1.00 76.99  ? 458 ILE F O   1 
ATOM   14114 C  CB  . ILE F 3 457 ? 133.853 169.569 118.513 1.00 71.44  ? 458 ILE F CB  1 
ATOM   14115 C  CG1 . ILE F 3 457 ? 134.039 170.304 117.190 1.00 70.73  ? 458 ILE F CG1 1 
ATOM   14116 C  CG2 . ILE F 3 457 ? 132.377 169.451 118.818 1.00 67.04  ? 458 ILE F CG2 1 
ATOM   14117 C  CD1 . ILE F 3 457 ? 133.077 169.869 116.121 1.00 61.87  ? 458 ILE F CD1 1 
ATOM   14118 N  N   . SER F 3 458 ? 133.818 169.650 121.851 1.00 77.31  ? 459 SER F N   1 
ATOM   14119 C  CA  . SER F 3 458 ? 133.755 168.828 123.051 1.00 76.96  ? 459 SER F CA  1 
ATOM   14120 C  C   . SER F 3 458 ? 132.297 168.529 123.361 1.00 78.71  ? 459 SER F C   1 
ATOM   14121 O  O   . SER F 3 458 ? 131.391 169.094 122.753 1.00 78.36  ? 459 SER F O   1 
ATOM   14122 C  CB  . SER F 3 458 ? 134.422 169.520 124.244 1.00 85.00  ? 459 SER F CB  1 
ATOM   14123 O  OG  . SER F 3 458 ? 135.759 169.882 123.945 1.00 86.99  ? 459 SER F OG  1 
ATOM   14124 N  N   . ARG F 3 459 ? 132.069 167.632 124.317 1.00 81.03  ? 460 ARG F N   1 
ATOM   14125 C  CA  . ARG F 3 459 ? 130.706 167.301 124.708 1.00 82.06  ? 460 ARG F CA  1 
ATOM   14126 C  C   . ARG F 3 459 ? 130.668 166.827 126.152 1.00 87.66  ? 460 ARG F C   1 
ATOM   14127 O  O   . ARG F 3 459 ? 131.683 166.390 126.698 1.00 85.73  ? 460 ARG F O   1 
ATOM   14128 C  CB  . ARG F 3 459 ? 130.107 166.230 123.785 1.00 74.71  ? 460 ARG F CB  1 
ATOM   14129 C  CG  . ARG F 3 459 ? 130.180 164.808 124.306 1.00 70.78  ? 460 ARG F CG  1 
ATOM   14130 C  CD  . ARG F 3 459 ? 131.585 164.250 124.268 1.00 72.20  ? 460 ARG F CD  1 
ATOM   14131 N  NE  . ARG F 3 459 ? 131.635 162.915 124.848 1.00 75.39  ? 460 ARG F NE  1 
ATOM   14132 C  CZ  . ARG F 3 459 ? 132.753 162.264 125.134 1.00 76.19  ? 460 ARG F CZ  1 
ATOM   14133 N  NH1 . ARG F 3 459 ? 133.940 162.806 124.924 1.00 79.16  ? 460 ARG F NH1 1 
ATOM   14134 N  NH2 . ARG F 3 459 ? 132.679 161.040 125.646 1.00 72.79  ? 460 ARG F NH2 1 
ATOM   14135 N  N   . ASP F 3 460 ? 129.488 166.921 126.764 1.00 94.16  ? 461 ASP F N   1 
ATOM   14136 C  CA  . ASP F 3 460 ? 129.251 166.398 128.103 1.00 96.07  ? 461 ASP F CA  1 
ATOM   14137 C  C   . ASP F 3 460 ? 127.826 165.873 128.195 1.00 96.02  ? 461 ASP F C   1 
ATOM   14138 O  O   . ASP F 3 460 ? 126.887 166.516 127.713 1.00 97.67  ? 461 ASP F O   1 
ATOM   14139 C  CB  . ASP F 3 460 ? 129.500 167.462 129.178 1.00 97.90  ? 461 ASP F CB  1 
ATOM   14140 C  CG  . ASP F 3 460 ? 128.885 168.799 128.831 1.00 101.81 ? 461 ASP F CG  1 
ATOM   14141 O  OD1 . ASP F 3 460 ? 128.313 168.926 127.729 1.00 101.19 ? 461 ASP F OD1 1 
ATOM   14142 O  OD2 . ASP F 3 460 ? 128.977 169.726 129.662 1.00 104.39 ? 461 ASP F OD2 1 
ATOM   14143 N  N   . ASN F 3 461 ? 127.673 164.705 128.814 1.00 96.25  ? 462 ASN F N   1 
ATOM   14144 C  CA  . ASN F 3 461 ? 126.374 164.064 128.945 1.00 94.48  ? 462 ASN F CA  1 
ATOM   14145 C  C   . ASN F 3 461 ? 125.650 164.443 130.227 1.00 98.53  ? 462 ASN F C   1 
ATOM   14146 O  O   . ASN F 3 461 ? 124.536 163.957 130.458 1.00 97.48  ? 462 ASN F O   1 
ATOM   14147 C  CB  . ASN F 3 461 ? 126.533 162.543 128.889 1.00 90.68  ? 462 ASN F CB  1 
ATOM   14148 C  CG  . ASN F 3 461 ? 127.370 162.092 127.714 1.00 84.91  ? 462 ASN F CG  1 
ATOM   14149 O  OD1 . ASN F 3 461 ? 128.573 162.344 127.665 1.00 82.24  ? 462 ASN F OD1 1 
ATOM   14150 N  ND2 . ASN F 3 461 ? 126.741 161.413 126.765 1.00 80.98  ? 462 ASN F ND2 1 
ATOM   14151 N  N   . ALA F 3 462 ? 126.253 165.286 131.063 1.00 102.88 ? 463 ALA F N   1 
ATOM   14152 C  CA  . ALA F 3 462 ? 125.615 165.727 132.296 1.00 104.74 ? 463 ALA F CA  1 
ATOM   14153 C  C   . ALA F 3 462 ? 124.319 166.456 131.974 1.00 105.94 ? 463 ALA F C   1 
ATOM   14154 O  O   . ALA F 3 462 ? 123.304 166.267 132.653 1.00 108.72 ? 463 ALA F O   1 
ATOM   14155 C  CB  . ALA F 3 462 ? 126.556 166.625 133.101 1.00 102.64 ? 463 ALA F CB  1 
ATOM   14156 N  N   . LYS F 3 463 ? 124.345 167.296 130.938 1.00 101.89 ? 464 LYS F N   1 
ATOM   14157 C  CA  . LYS F 3 463 ? 123.136 167.940 130.443 1.00 103.48 ? 464 LYS F CA  1 
ATOM   14158 C  C   . LYS F 3 463 ? 122.942 167.712 128.948 1.00 101.03 ? 464 LYS F C   1 
ATOM   14159 O  O   . LYS F 3 463 ? 122.174 168.441 128.314 1.00 100.11 ? 464 LYS F O   1 
ATOM   14160 C  CB  . LYS F 3 463 ? 123.149 169.438 130.756 1.00 107.06 ? 464 LYS F CB  1 
ATOM   14161 C  CG  . LYS F 3 463 ? 124.463 170.136 130.464 1.00 106.13 ? 464 LYS F CG  1 
ATOM   14162 C  CD  . LYS F 3 463 ? 124.344 171.629 130.742 1.00 107.85 ? 464 LYS F CD  1 
ATOM   14163 C  CE  . LYS F 3 463 ? 125.659 172.349 130.508 1.00 105.52 ? 464 LYS F CE  1 
ATOM   14164 N  NZ  . LYS F 3 463 ? 126.729 171.883 131.431 1.00 98.47  ? 464 LYS F NZ  1 
ATOM   14165 N  N   . ASN F 3 464 ? 123.627 166.721 128.377 1.00 97.72  ? 465 ASN F N   1 
ATOM   14166 C  CA  . ASN F 3 464 ? 123.494 166.367 126.964 1.00 95.95  ? 465 ASN F CA  1 
ATOM   14167 C  C   . ASN F 3 464 ? 123.755 167.578 126.066 1.00 94.28  ? 465 ASN F C   1 
ATOM   14168 O  O   . ASN F 3 464 ? 122.875 168.054 125.347 1.00 91.62  ? 465 ASN F O   1 
ATOM   14169 C  CB  . ASN F 3 464 ? 122.113 165.765 126.683 1.00 95.33  ? 465 ASN F CB  1 
ATOM   14170 C  CG  . ASN F 3 464 ? 121.877 164.471 127.426 1.00 95.46  ? 465 ASN F CG  1 
ATOM   14171 O  OD1 . ASN F 3 464 ? 120.969 164.372 128.247 1.00 96.34  ? 465 ASN F OD1 1 
ATOM   14172 N  ND2 . ASN F 3 464 ? 122.688 163.466 127.132 1.00 96.77  ? 465 ASN F ND2 1 
ATOM   14173 N  N   . THR F 3 465 ? 124.984 168.084 126.125 1.00 95.10  ? 466 THR F N   1 
ATOM   14174 C  CA  . THR F 3 465 ? 125.339 169.291 125.394 1.00 90.35  ? 466 THR F CA  1 
ATOM   14175 C  C   . THR F 3 465 ? 126.681 169.116 124.697 1.00 88.03  ? 466 THR F C   1 
ATOM   14176 O  O   . THR F 3 465 ? 127.534 168.341 125.138 1.00 87.57  ? 466 THR F O   1 
ATOM   14177 C  CB  . THR F 3 465 ? 125.374 170.503 126.333 1.00 91.46  ? 466 THR F CB  1 
ATOM   14178 O  OG1 . THR F 3 465 ? 124.232 170.460 127.196 1.00 95.80  ? 466 THR F OG1 1 
ATOM   14179 C  CG2 . THR F 3 465 ? 125.324 171.793 125.547 1.00 88.39  ? 466 THR F CG2 1 
ATOM   14180 N  N   . VAL F 3 466 ? 126.851 169.831 123.585 1.00 88.14  ? 467 VAL F N   1 
ATOM   14181 C  CA  . VAL F 3 466 ? 128.096 169.845 122.828 1.00 85.01  ? 467 VAL F CA  1 
ATOM   14182 C  C   . VAL F 3 466 ? 128.544 171.289 122.664 1.00 85.78  ? 467 VAL F C   1 
ATOM   14183 O  O   . VAL F 3 466 ? 127.737 172.222 122.706 1.00 87.77  ? 467 VAL F O   1 
ATOM   14184 C  CB  . VAL F 3 466 ? 127.953 169.157 121.454 1.00 76.53  ? 467 VAL F CB  1 
ATOM   14185 C  CG1 . VAL F 3 466 ? 127.536 167.715 121.627 1.00 72.86  ? 467 VAL F CG1 1 
ATOM   14186 C  CG2 . VAL F 3 466 ? 126.950 169.882 120.601 1.00 74.72  ? 467 VAL F CG2 1 
ATOM   14187 N  N   . TYR F 3 467 ? 129.847 171.470 122.480 1.00 83.78  ? 468 TYR F N   1 
ATOM   14188 C  CA  . TYR F 3 467 ? 130.464 172.785 122.478 1.00 86.58  ? 468 TYR F CA  1 
ATOM   14189 C  C   . TYR F 3 467 ? 131.445 172.909 121.326 1.00 82.13  ? 468 TYR F C   1 
ATOM   14190 O  O   . TYR F 3 467 ? 132.254 172.007 121.085 1.00 78.22  ? 468 TYR F O   1 
ATOM   14191 C  CB  . TYR F 3 467 ? 131.196 173.052 123.792 1.00 88.83  ? 468 TYR F CB  1 
ATOM   14192 C  CG  . TYR F 3 467 ? 130.328 172.906 125.015 1.00 93.43  ? 468 TYR F CG  1 
ATOM   14193 C  CD1 . TYR F 3 467 ? 129.289 173.788 125.257 1.00 91.39  ? 468 TYR F CD1 1 
ATOM   14194 C  CD2 . TYR F 3 467 ? 130.555 171.892 125.932 1.00 93.34  ? 468 TYR F CD2 1 
ATOM   14195 C  CE1 . TYR F 3 467 ? 128.498 173.663 126.370 1.00 93.23  ? 468 TYR F CE1 1 
ATOM   14196 C  CE2 . TYR F 3 467 ? 129.768 171.761 127.051 1.00 94.96  ? 468 TYR F CE2 1 
ATOM   14197 C  CZ  . TYR F 3 467 ? 128.740 172.651 127.262 1.00 97.61  ? 468 TYR F CZ  1 
ATOM   14198 O  OH  . TYR F 3 467 ? 127.947 172.531 128.375 1.00 103.83 ? 468 TYR F OH  1 
ATOM   14199 N  N   . LEU F 3 468 ? 131.377 174.047 120.637 1.00 82.92  ? 469 LEU F N   1 
ATOM   14200 C  CA  . LEU F 3 468 ? 132.320 174.423 119.590 1.00 80.43  ? 469 LEU F CA  1 
ATOM   14201 C  C   . LEU F 3 468 ? 133.110 175.630 120.078 1.00 86.04  ? 469 LEU F C   1 
ATOM   14202 O  O   . LEU F 3 468 ? 132.546 176.716 120.252 1.00 87.31  ? 469 LEU F O   1 
ATOM   14203 C  CB  . LEU F 3 468 ? 131.595 174.743 118.287 1.00 77.41  ? 469 LEU F CB  1 
ATOM   14204 C  CG  . LEU F 3 468 ? 132.474 175.061 117.078 1.00 77.36  ? 469 LEU F CG  1 
ATOM   14205 C  CD1 . LEU F 3 468 ? 133.113 173.797 116.546 1.00 72.83  ? 469 LEU F CD1 1 
ATOM   14206 C  CD2 . LEU F 3 468 ? 131.667 175.759 115.995 1.00 75.92  ? 469 LEU F CD2 1 
ATOM   14207 N  N   . GLU F 3 469 ? 134.406 175.443 120.297 1.00 89.03  ? 470 GLU F N   1 
ATOM   14208 C  CA  . GLU F 3 469 ? 135.302 176.511 120.717 1.00 90.58  ? 470 GLU F CA  1 
ATOM   14209 C  C   . GLU F 3 469 ? 136.037 177.037 119.492 1.00 91.49  ? 470 GLU F C   1 
ATOM   14210 O  O   . GLU F 3 469 ? 136.736 176.276 118.815 1.00 92.57  ? 470 GLU F O   1 
ATOM   14211 C  CB  . GLU F 3 469 ? 136.297 176.004 121.759 1.00 93.87  ? 470 GLU F CB  1 
ATOM   14212 C  CG  . GLU F 3 469 ? 135.679 175.140 122.845 1.00 98.97  ? 470 GLU F CG  1 
ATOM   14213 C  CD  . GLU F 3 469 ? 136.719 174.544 123.775 1.00 106.17 ? 470 GLU F CD  1 
ATOM   14214 O  OE1 . GLU F 3 469 ? 137.916 174.854 123.602 1.00 109.54 ? 470 GLU F OE1 1 
ATOM   14215 O  OE2 . GLU F 3 469 ? 136.344 173.766 124.678 1.00 104.59 ? 470 GLU F OE2 1 
ATOM   14216 N  N   . MET F 3 470 ? 135.884 178.328 119.214 1.00 92.83  ? 471 MET F N   1 
ATOM   14217 C  CA  . MET F 3 470 ? 136.507 178.960 118.059 1.00 96.41  ? 471 MET F CA  1 
ATOM   14218 C  C   . MET F 3 470 ? 137.742 179.735 118.495 1.00 101.14 ? 471 MET F C   1 
ATOM   14219 O  O   . MET F 3 470 ? 137.672 180.561 119.410 1.00 104.16 ? 471 MET F O   1 
ATOM   14220 C  CB  . MET F 3 470 ? 135.533 179.899 117.345 1.00 95.65  ? 471 MET F CB  1 
ATOM   14221 C  CG  . MET F 3 470 ? 134.418 179.196 116.604 1.00 89.82  ? 471 MET F CG  1 
ATOM   14222 S  SD  . MET F 3 470 ? 133.173 178.544 117.719 1.00 99.98  ? 471 MET F SD  1 
ATOM   14223 C  CE  . MET F 3 470 ? 132.222 180.020 118.051 1.00 100.60 ? 471 MET F CE  1 
ATOM   14224 N  N   . ASN F 3 471 ? 138.867 179.466 117.838 1.00 102.95 ? 472 ASN F N   1 
ATOM   14225 C  CA  . ASN F 3 471 ? 140.115 180.164 118.099 1.00 105.96 ? 472 ASN F CA  1 
ATOM   14226 C  C   . ASN F 3 471 ? 140.701 180.657 116.787 1.00 108.09 ? 472 ASN F C   1 
ATOM   14227 O  O   . ASN F 3 471 ? 140.549 180.016 115.743 1.00 110.53 ? 472 ASN F O   1 
ATOM   14228 C  CB  . ASN F 3 471 ? 141.124 179.265 118.817 1.00 104.36 ? 472 ASN F CB  1 
ATOM   14229 C  CG  . ASN F 3 471 ? 140.681 178.900 120.211 1.00 106.65 ? 472 ASN F CG  1 
ATOM   14230 O  OD1 . ASN F 3 471 ? 139.957 179.654 120.858 1.00 106.77 ? 472 ASN F OD1 1 
ATOM   14231 N  ND2 . ASN F 3 471 ? 141.112 177.740 120.686 1.00 108.33 ? 472 ASN F ND2 1 
ATOM   14232 N  N   . ASN F 3 472 ? 141.385 181.801 116.854 1.00 106.66 ? 473 ASN F N   1 
ATOM   14233 C  CA  . ASN F 3 472 ? 141.980 182.443 115.683 1.00 109.71 ? 473 ASN F CA  1 
ATOM   14234 C  C   . ASN F 3 472 ? 140.908 182.775 114.644 1.00 109.69 ? 473 ASN F C   1 
ATOM   14235 O  O   . ASN F 3 472 ? 140.919 182.284 113.514 1.00 110.09 ? 473 ASN F O   1 
ATOM   14236 C  CB  . ASN F 3 472 ? 143.086 181.570 115.079 1.00 108.32 ? 473 ASN F CB  1 
ATOM   14237 C  CG  . ASN F 3 472 ? 144.032 181.019 116.125 1.00 107.96 ? 473 ASN F CG  1 
ATOM   14238 O  OD1 . ASN F 3 472 ? 143.662 180.152 116.915 1.00 106.99 ? 473 ASN F OD1 1 
ATOM   14239 N  ND2 . ASN F 3 472 ? 145.264 181.508 116.126 1.00 105.34 ? 473 ASN F ND2 1 
ATOM   14240 N  N   . LEU F 3 473 ? 139.977 183.632 115.052 1.00 107.93 ? 474 LEU F N   1 
ATOM   14241 C  CA  . LEU F 3 473 ? 138.884 184.041 114.183 1.00 106.94 ? 474 LEU F CA  1 
ATOM   14242 C  C   . LEU F 3 473 ? 139.408 184.828 112.987 1.00 106.76 ? 474 LEU F C   1 
ATOM   14243 O  O   . LEU F 3 473 ? 140.450 185.484 113.051 1.00 108.30 ? 474 LEU F O   1 
ATOM   14244 C  CB  . LEU F 3 473 ? 137.870 184.889 114.954 1.00 106.24 ? 474 LEU F CB  1 
ATOM   14245 C  CG  . LEU F 3 473 ? 136.862 184.211 115.891 1.00 108.49 ? 474 LEU F CG  1 
ATOM   14246 C  CD1 . LEU F 3 473 ? 136.060 183.153 115.152 1.00 103.76 ? 474 LEU F CD1 1 
ATOM   14247 C  CD2 . LEU F 3 473 ? 137.530 183.623 117.131 1.00 107.52 ? 474 LEU F CD2 1 
ATOM   14248 N  N   . LYS F 3 474 ? 138.675 184.748 111.886 1.00 107.86 ? 475 LYS F N   1 
ATOM   14249 C  CA  . LYS F 3 474 ? 139.009 185.434 110.649 1.00 108.66 ? 475 LYS F CA  1 
ATOM   14250 C  C   . LYS F 3 474 ? 137.747 186.062 110.084 1.00 109.13 ? 475 LYS F C   1 
ATOM   14251 O  O   . LYS F 3 474 ? 136.635 185.660 110.441 1.00 111.00 ? 475 LYS F O   1 
ATOM   14252 C  CB  . LYS F 3 474 ? 139.628 184.478 109.620 1.00 108.07 ? 475 LYS F CB  1 
ATOM   14253 C  CG  . LYS F 3 474 ? 141.047 184.056 109.945 1.00 106.25 ? 475 LYS F CG  1 
ATOM   14254 C  CD  . LYS F 3 474 ? 141.742 183.475 108.727 1.00 106.98 ? 475 LYS F CD  1 
ATOM   14255 C  CE  . LYS F 3 474 ? 140.996 182.269 108.187 1.00 112.50 ? 475 LYS F CE  1 
ATOM   14256 N  NZ  . LYS F 3 474 ? 141.021 181.139 109.153 1.00 113.77 ? 475 LYS F NZ  1 
ATOM   14257 N  N   . PRO F 3 475 ? 137.884 187.063 109.213 1.00 109.95 ? 476 PRO F N   1 
ATOM   14258 C  CA  . PRO F 3 475 ? 136.694 187.606 108.541 1.00 109.40 ? 476 PRO F CA  1 
ATOM   14259 C  C   . PRO F 3 475 ? 135.985 186.593 107.663 1.00 108.68 ? 476 PRO F C   1 
ATOM   14260 O  O   . PRO F 3 475 ? 134.817 186.806 107.319 1.00 109.48 ? 476 PRO F O   1 
ATOM   14261 C  CB  . PRO F 3 475 ? 137.255 188.773 107.717 1.00 108.24 ? 476 PRO F CB  1 
ATOM   14262 C  CG  . PRO F 3 475 ? 138.709 188.469 107.565 1.00 109.72 ? 476 PRO F CG  1 
ATOM   14263 C  CD  . PRO F 3 475 ? 139.104 187.799 108.841 1.00 109.88 ? 476 PRO F CD  1 
ATOM   14264 N  N   . GLU F 3 476 ? 136.654 185.502 107.283 1.00 108.32 ? 477 GLU F N   1 
ATOM   14265 C  CA  . GLU F 3 476 ? 136.034 184.464 106.469 1.00 109.17 ? 477 GLU F CA  1 
ATOM   14266 C  C   . GLU F 3 476 ? 135.025 183.621 107.238 1.00 105.84 ? 477 GLU F C   1 
ATOM   14267 O  O   . GLU F 3 476 ? 134.309 182.829 106.616 1.00 102.85 ? 477 GLU F O   1 
ATOM   14268 C  CB  . GLU F 3 476 ? 137.110 183.551 105.881 1.00 112.14 ? 477 GLU F CB  1 
ATOM   14269 C  CG  . GLU F 3 476 ? 138.120 184.266 105.004 1.00 118.08 ? 477 GLU F CG  1 
ATOM   14270 C  CD  . GLU F 3 476 ? 139.325 183.404 104.685 1.00 124.84 ? 477 GLU F CD  1 
ATOM   14271 O  OE1 . GLU F 3 476 ? 139.441 182.306 105.269 1.00 125.24 ? 477 GLU F OE1 1 
ATOM   14272 O  OE2 . GLU F 3 476 ? 140.157 183.822 103.852 1.00 124.21 ? 477 GLU F OE2 1 
ATOM   14273 N  N   . ASP F 3 477 ? 134.947 183.765 108.557 1.00 103.88 ? 478 ASP F N   1 
ATOM   14274 C  CA  . ASP F 3 477 ? 134.078 182.935 109.381 1.00 98.16  ? 478 ASP F CA  1 
ATOM   14275 C  C   . ASP F 3 477 ? 132.696 183.538 109.587 1.00 99.53  ? 478 ASP F C   1 
ATOM   14276 O  O   . ASP F 3 477 ? 131.900 182.983 110.349 1.00 98.35  ? 478 ASP F O   1 
ATOM   14277 C  CB  . ASP F 3 477 ? 134.732 182.679 110.738 1.00 98.11  ? 478 ASP F CB  1 
ATOM   14278 C  CG  . ASP F 3 477 ? 136.136 182.142 110.609 1.00 101.51 ? 478 ASP F CG  1 
ATOM   14279 O  OD1 . ASP F 3 477 ? 136.463 181.586 109.543 1.00 101.12 ? 478 ASP F OD1 1 
ATOM   14280 O  OD2 . ASP F 3 477 ? 136.912 182.269 111.575 1.00 102.87 ? 478 ASP F OD2 1 
ATOM   14281 N  N   . THR F 3 478 ? 132.395 184.659 108.940 1.00 102.62 ? 479 THR F N   1 
ATOM   14282 C  CA  . THR F 3 478 ? 131.100 185.313 109.101 1.00 101.76 ? 479 THR F CA  1 
ATOM   14283 C  C   . THR F 3 478 ? 130.032 184.469 108.421 1.00 100.74 ? 479 THR F C   1 
ATOM   14284 O  O   . THR F 3 478 ? 129.859 184.524 107.202 1.00 102.56 ? 479 THR F O   1 
ATOM   14285 C  CB  . THR F 3 478 ? 131.139 186.721 108.520 1.00 103.84 ? 479 THR F CB  1 
ATOM   14286 O  OG1 . THR F 3 478 ? 131.678 186.673 107.195 1.00 105.17 ? 479 THR F OG1 1 
ATOM   14287 C  CG2 . THR F 3 478 ? 132.009 187.617 109.375 1.00 104.73 ? 479 THR F CG2 1 
ATOM   14288 N  N   . ALA F 3 479 ? 129.307 183.685 109.213 1.00 98.99  ? 480 ALA F N   1 
ATOM   14289 C  CA  . ALA F 3 479 ? 128.281 182.800 108.685 1.00 95.58  ? 480 ALA F CA  1 
ATOM   14290 C  C   . ALA F 3 479 ? 127.297 182.474 109.796 1.00 93.09  ? 480 ALA F C   1 
ATOM   14291 O  O   . ALA F 3 479 ? 127.592 182.651 110.980 1.00 91.40  ? 480 ALA F O   1 
ATOM   14292 C  CB  . ALA F 3 479 ? 128.892 181.519 108.111 1.00 92.27  ? 480 ALA F CB  1 
ATOM   14293 N  N   . VAL F 3 480 ? 126.121 181.998 109.400 1.00 93.84  ? 481 VAL F N   1 
ATOM   14294 C  CA  . VAL F 3 480 ? 125.101 181.577 110.354 1.00 91.87  ? 481 VAL F CA  1 
ATOM   14295 C  C   . VAL F 3 480 ? 125.322 180.103 110.672 1.00 87.98  ? 481 VAL F C   1 
ATOM   14296 O  O   . VAL F 3 480 ? 125.360 179.262 109.769 1.00 87.42  ? 481 VAL F O   1 
ATOM   14297 C  CB  . VAL F 3 480 ? 123.687 181.829 109.808 1.00 89.38  ? 481 VAL F CB  1 
ATOM   14298 C  CG1 . VAL F 3 480 ? 123.611 181.488 108.336 1.00 90.11  ? 481 VAL F CG1 1 
ATOM   14299 C  CG2 . VAL F 3 480 ? 122.669 181.028 110.591 1.00 86.65  ? 481 VAL F CG2 1 
ATOM   14300 N  N   . TYR F 3 481 ? 125.478 179.790 111.954 1.00 84.93  ? 482 TYR F N   1 
ATOM   14301 C  CA  . TYR F 3 481 ? 125.910 178.469 112.388 1.00 80.93  ? 482 TYR F CA  1 
ATOM   14302 C  C   . TYR F 3 481 ? 124.731 177.634 112.865 1.00 80.71  ? 482 TYR F C   1 
ATOM   14303 O  O   . TYR F 3 481 ? 123.859 178.122 113.590 1.00 86.42  ? 482 TYR F O   1 
ATOM   14304 C  CB  . TYR F 3 481 ? 126.952 178.579 113.501 1.00 81.59  ? 482 TYR F CB  1 
ATOM   14305 C  CG  . TYR F 3 481 ? 128.322 178.977 113.007 1.00 84.12  ? 482 TYR F CG  1 
ATOM   14306 C  CD1 . TYR F 3 481 ? 128.584 180.276 112.598 1.00 86.77  ? 482 TYR F CD1 1 
ATOM   14307 C  CD2 . TYR F 3 481 ? 129.354 178.056 112.953 1.00 80.26  ? 482 TYR F CD2 1 
ATOM   14308 C  CE1 . TYR F 3 481 ? 129.833 180.643 112.141 1.00 85.23  ? 482 TYR F CE1 1 
ATOM   14309 C  CE2 . TYR F 3 481 ? 130.606 178.414 112.502 1.00 78.60  ? 482 TYR F CE2 1 
ATOM   14310 C  CZ  . TYR F 3 481 ? 130.840 179.708 112.097 1.00 80.17  ? 482 TYR F CZ  1 
ATOM   14311 O  OH  . TYR F 3 481 ? 132.087 180.061 111.647 1.00 81.31  ? 482 TYR F OH  1 
ATOM   14312 N  N   . TYR F 3 482 ? 124.720 176.369 112.460 1.00 74.07  ? 483 TYR F N   1 
ATOM   14313 C  CA  . TYR F 3 482 ? 123.691 175.415 112.832 1.00 72.27  ? 483 TYR F CA  1 
ATOM   14314 C  C   . TYR F 3 482 ? 124.331 174.196 113.475 1.00 69.66  ? 483 TYR F C   1 
ATOM   14315 O  O   . TYR F 3 482 ? 125.484 173.856 113.199 1.00 67.84  ? 483 TYR F O   1 
ATOM   14316 C  CB  . TYR F 3 482 ? 122.871 174.958 111.629 1.00 69.31  ? 483 TYR F CB  1 
ATOM   14317 C  CG  . TYR F 3 482 ? 122.177 176.058 110.873 1.00 76.96  ? 483 TYR F CG  1 
ATOM   14318 C  CD1 . TYR F 3 482 ? 122.800 176.689 109.812 1.00 79.28  ? 483 TYR F CD1 1 
ATOM   14319 C  CD2 . TYR F 3 482 ? 120.889 176.445 111.201 1.00 83.17  ? 483 TYR F CD2 1 
ATOM   14320 C  CE1 . TYR F 3 482 ? 122.170 177.685 109.109 1.00 83.29  ? 483 TYR F CE1 1 
ATOM   14321 C  CE2 . TYR F 3 482 ? 120.248 177.442 110.501 1.00 85.45  ? 483 TYR F CE2 1 
ATOM   14322 C  CZ  . TYR F 3 482 ? 120.896 178.058 109.455 1.00 86.46  ? 483 TYR F CZ  1 
ATOM   14323 O  OH  . TYR F 3 482 ? 120.268 179.056 108.751 1.00 88.27  ? 483 TYR F OH  1 
ATOM   14324 N  N   . CYS F 3 483 ? 123.562 173.548 114.339 1.00 66.62  ? 484 CYS F N   1 
ATOM   14325 C  CA  . CYS F 3 483 ? 123.934 172.300 114.985 1.00 59.27  ? 484 CYS F CA  1 
ATOM   14326 C  C   . CYS F 3 483 ? 122.897 171.256 114.604 1.00 59.81  ? 484 CYS F C   1 
ATOM   14327 O  O   . CYS F 3 483 ? 121.695 171.531 114.660 1.00 64.85  ? 484 CYS F O   1 
ATOM   14328 C  CB  . CYS F 3 483 ? 123.993 172.487 116.497 1.00 63.91  ? 484 CYS F CB  1 
ATOM   14329 S  SG  . CYS F 3 483 ? 124.106 171.001 117.481 1.00 77.59  ? 484 CYS F SG  1 
ATOM   14330 N  N   . ALA F 3 484 ? 123.350 170.069 114.205 1.00 53.63  ? 485 ALA F N   1 
ATOM   14331 C  CA  . ALA F 3 484 ? 122.435 169.058 113.698 1.00 47.93  ? 485 ALA F CA  1 
ATOM   14332 C  C   . ALA F 3 484 ? 122.811 167.687 114.235 1.00 46.12  ? 485 ALA F C   1 
ATOM   14333 O  O   . ALA F 3 484 ? 123.935 167.456 114.675 1.00 49.28  ? 485 ALA F O   1 
ATOM   14334 C  CB  . ALA F 3 484 ? 122.422 169.033 112.170 1.00 44.82  ? 485 ALA F CB  1 
ATOM   14335 N  N   . ALA F 3 485 ? 121.845 166.777 114.192 1.00 41.65  ? 486 ALA F N   1 
ATOM   14336 C  CA  . ALA F 3 485 ? 122.024 165.415 114.677 1.00 36.18  ? 486 ALA F CA  1 
ATOM   14337 C  C   . ALA F 3 485 ? 121.930 164.430 113.522 1.00 39.42  ? 486 ALA F C   1 
ATOM   14338 O  O   . ALA F 3 485 ? 121.132 164.617 112.601 1.00 44.61  ? 486 ALA F O   1 
ATOM   14339 C  CB  . ALA F 3 485 ? 120.983 165.067 115.739 1.00 40.70  ? 486 ALA F CB  1 
ATOM   14340 N  N   . LYS F 3 486 ? 122.746 163.382 113.570 1.00 38.33  ? 487 LYS F N   1 
ATOM   14341 C  CA  . LYS F 3 486 ? 122.799 162.388 112.509 1.00 35.38  ? 487 LYS F CA  1 
ATOM   14342 C  C   . LYS F 3 486 ? 122.542 161.001 113.077 1.00 35.96  ? 487 LYS F C   1 
ATOM   14343 O  O   . LYS F 3 486 ? 123.094 160.638 114.116 1.00 38.31  ? 487 LYS F O   1 
ATOM   14344 C  CB  . LYS F 3 486 ? 124.154 162.430 111.803 1.00 35.13  ? 487 LYS F CB  1 
ATOM   14345 C  CG  . LYS F 3 486 ? 124.413 161.299 110.834 1.00 37.76  ? 487 LYS F CG  1 
ATOM   14346 C  CD  . LYS F 3 486 ? 125.734 161.510 110.129 1.00 34.53  ? 487 LYS F CD  1 
ATOM   14347 C  CE  . LYS F 3 486 ? 126.186 160.265 109.405 1.00 31.91  ? 487 LYS F CE  1 
ATOM   14348 N  NZ  . LYS F 3 486 ? 126.473 159.153 110.347 1.00 32.22  ? 487 LYS F NZ  1 
ATOM   14349 N  N   . GLY F 3 487 ? 121.718 160.224 112.383 1.00 37.88  ? 488 GLY F N   1 
ATOM   14350 C  CA  . GLY F 3 487 ? 121.369 158.893 112.828 1.00 35.35  ? 488 GLY F CA  1 
ATOM   14351 C  C   . GLY F 3 487 ? 122.530 157.923 112.717 1.00 34.67  ? 488 GLY F C   1 
ATOM   14352 O  O   . GLY F 3 487 ? 123.636 158.255 112.297 1.00 37.07  ? 488 GLY F O   1 
ATOM   14353 N  N   . ARG F 3 488 ? 122.263 156.683 113.121 1.00 33.46  ? 489 ARG F N   1 
ATOM   14354 C  CA  . ARG F 3 488 ? 123.332 155.696 113.194 1.00 32.08  ? 489 ARG F CA  1 
ATOM   14355 C  C   . ARG F 3 488 ? 123.717 155.159 111.820 1.00 32.52  ? 489 ARG F C   1 
ATOM   14356 O  O   . ARG F 3 488 ? 124.897 154.904 111.566 1.00 36.74  ? 489 ARG F O   1 
ATOM   14357 C  CB  . ARG F 3 488 ? 122.926 154.554 114.122 1.00 30.50  ? 489 ARG F CB  1 
ATOM   14358 C  CG  . ARG F 3 488 ? 124.038 153.565 114.369 1.00 29.41  ? 489 ARG F CG  1 
ATOM   14359 C  CD  . ARG F 3 488 ? 123.738 152.638 115.532 1.00 33.82  ? 489 ARG F CD  1 
ATOM   14360 N  NE  . ARG F 3 488 ? 124.161 153.196 116.809 1.00 33.86  ? 489 ARG F NE  1 
ATOM   14361 C  CZ  . ARG F 3 488 ? 123.337 153.692 117.721 1.00 37.61  ? 489 ARG F CZ  1 
ATOM   14362 N  NH1 . ARG F 3 488 ? 122.030 153.706 117.536 1.00 39.52  ? 489 ARG F NH1 1 
ATOM   14363 N  NH2 . ARG F 3 488 ? 123.839 154.179 118.850 1.00 37.55  ? 489 ARG F NH2 1 
ATOM   14364 N  N   . TYR F 3 489 ? 122.752 154.991 110.919 1.00 30.55  ? 490 TYR F N   1 
ATOM   14365 C  CA  . TYR F 3 489 ? 122.999 154.404 109.608 1.00 29.26  ? 490 TYR F CA  1 
ATOM   14366 C  C   . TYR F 3 489 ? 122.665 155.382 108.489 1.00 32.01  ? 490 TYR F C   1 
ATOM   14367 O  O   . TYR F 3 489 ? 122.086 155.007 107.471 1.00 34.98  ? 490 TYR F O   1 
ATOM   14368 C  CB  . TYR F 3 489 ? 122.203 153.114 109.426 1.00 26.02  ? 490 TYR F CB  1 
ATOM   14369 C  CG  . TYR F 3 489 ? 122.533 152.021 110.412 1.00 26.54  ? 490 TYR F CG  1 
ATOM   14370 C  CD1 . TYR F 3 489 ? 123.692 151.277 110.287 1.00 27.22  ? 490 TYR F CD1 1 
ATOM   14371 C  CD2 . TYR F 3 489 ? 121.677 151.723 111.458 1.00 26.94  ? 490 TYR F CD2 1 
ATOM   14372 C  CE1 . TYR F 3 489 ? 123.994 150.278 111.179 1.00 26.58  ? 490 TYR F CE1 1 
ATOM   14373 C  CE2 . TYR F 3 489 ? 121.974 150.727 112.356 1.00 26.94  ? 490 TYR F CE2 1 
ATOM   14374 C  CZ  . TYR F 3 489 ? 123.135 150.009 112.211 1.00 26.74  ? 490 TYR F CZ  1 
ATOM   14375 O  OH  . TYR F 3 489 ? 123.439 149.010 113.104 1.00 27.29  ? 490 TYR F OH  1 
ATOM   14376 N  N   . SER F 3 490 ? 123.039 156.647 108.653 1.00 31.00  ? 491 SER F N   1 
ATOM   14377 C  CA  . SER F 3 490 ? 122.642 157.697 107.726 1.00 28.04  ? 491 SER F CA  1 
ATOM   14378 C  C   . SER F 3 490 ? 123.731 158.076 106.734 1.00 31.29  ? 491 SER F C   1 
ATOM   14379 O  O   . SER F 3 490 ? 123.597 159.089 106.048 1.00 37.94  ? 491 SER F O   1 
ATOM   14380 C  CB  . SER F 3 490 ? 122.196 158.935 108.495 1.00 34.46  ? 491 SER F CB  1 
ATOM   14381 O  OG  . SER F 3 490 ? 120.955 158.709 109.131 1.00 38.50  ? 491 SER F OG  1 
ATOM   14382 N  N   . GLY F 3 491 ? 124.807 157.306 106.648 1.00 30.40  ? 492 GLY F N   1 
ATOM   14383 C  CA  . GLY F 3 491 ? 125.784 157.517 105.600 1.00 30.27  ? 492 GLY F CA  1 
ATOM   14384 C  C   . GLY F 3 491 ? 126.905 158.479 105.926 1.00 30.55  ? 492 GLY F C   1 
ATOM   14385 O  O   . GLY F 3 491 ? 127.426 158.483 107.042 1.00 36.63  ? 492 GLY F O   1 
ATOM   14386 N  N   . GLY F 3 492 ? 127.280 159.303 104.953 1.00 29.24  ? 493 GLY F N   1 
ATOM   14387 C  CA  . GLY F 3 492 ? 128.455 160.132 105.098 1.00 32.19  ? 493 GLY F CA  1 
ATOM   14388 C  C   . GLY F 3 492 ? 128.294 161.204 106.155 1.00 35.86  ? 493 GLY F C   1 
ATOM   14389 O  O   . GLY F 3 492 ? 127.195 161.620 106.510 1.00 40.62  ? 493 GLY F O   1 
ATOM   14390 N  N   . LEU F 3 493 ? 129.434 161.670 106.652 1.00 37.10  ? 494 LEU F N   1 
ATOM   14391 C  CA  . LEU F 3 493 ? 129.462 162.601 107.768 1.00 34.82  ? 494 LEU F CA  1 
ATOM   14392 C  C   . LEU F 3 493 ? 129.540 164.057 107.338 1.00 38.45  ? 494 LEU F C   1 
ATOM   14393 O  O   . LEU F 3 493 ? 129.229 164.940 108.141 1.00 43.85  ? 494 LEU F O   1 
ATOM   14394 C  CB  . LEU F 3 493 ? 130.653 162.279 108.670 1.00 29.12  ? 494 LEU F CB  1 
ATOM   14395 C  CG  . LEU F 3 493 ? 130.635 162.803 110.098 1.00 28.60  ? 494 LEU F CG  1 
ATOM   14396 C  CD1 . LEU F 3 493 ? 129.417 162.293 110.821 1.00 32.48  ? 494 LEU F CD1 1 
ATOM   14397 C  CD2 . LEU F 3 493 ? 131.890 162.379 110.810 1.00 29.14  ? 494 LEU F CD2 1 
ATOM   14398 N  N   . TYR F 3 494 ? 129.925 164.329 106.094 1.00 39.79  ? 495 TYR F N   1 
ATOM   14399 C  CA  . TYR F 3 494 ? 130.199 165.680 105.630 1.00 40.31  ? 495 TYR F CA  1 
ATOM   14400 C  C   . TYR F 3 494 ? 129.054 166.274 104.828 1.00 40.50  ? 495 TYR F C   1 
ATOM   14401 O  O   . TYR F 3 494 ? 129.228 167.327 104.209 1.00 45.14  ? 495 TYR F O   1 
ATOM   14402 C  CB  . TYR F 3 494 ? 131.476 165.696 104.786 1.00 42.02  ? 495 TYR F CB  1 
ATOM   14403 C  CG  . TYR F 3 494 ? 132.622 164.922 105.394 1.00 44.11  ? 495 TYR F CG  1 
ATOM   14404 C  CD1 . TYR F 3 494 ? 132.721 163.549 105.230 1.00 47.62  ? 495 TYR F CD1 1 
ATOM   14405 C  CD2 . TYR F 3 494 ? 133.603 165.565 106.128 1.00 48.98  ? 495 TYR F CD2 1 
ATOM   14406 C  CE1 . TYR F 3 494 ? 133.758 162.839 105.786 1.00 52.17  ? 495 TYR F CE1 1 
ATOM   14407 C  CE2 . TYR F 3 494 ? 134.646 164.864 106.687 1.00 55.39  ? 495 TYR F CE2 1 
ATOM   14408 C  CZ  . TYR F 3 494 ? 134.719 163.500 106.514 1.00 59.16  ? 495 TYR F CZ  1 
ATOM   14409 O  OH  . TYR F 3 494 ? 135.759 162.790 107.066 1.00 60.24  ? 495 TYR F OH  1 
ATOM   14410 N  N   . TYR F 3 495 ? 127.894 165.629 104.817 1.00 39.67  ? 496 TYR F N   1 
ATOM   14411 C  CA  . TYR F 3 495 ? 126.798 166.033 103.948 1.00 40.74  ? 496 TYR F CA  1 
ATOM   14412 C  C   . TYR F 3 495 ? 125.608 166.475 104.785 1.00 42.83  ? 496 TYR F C   1 
ATOM   14413 O  O   . TYR F 3 495 ? 125.116 165.691 105.613 1.00 42.68  ? 496 TYR F O   1 
ATOM   14414 C  CB  . TYR F 3 495 ? 126.418 164.885 103.018 1.00 36.57  ? 496 TYR F CB  1 
ATOM   14415 C  CG  . TYR F 3 495 ? 127.623 164.297 102.330 1.00 40.69  ? 496 TYR F CG  1 
ATOM   14416 C  CD1 . TYR F 3 495 ? 128.174 164.909 101.219 1.00 39.46  ? 496 TYR F CD1 1 
ATOM   14417 C  CD2 . TYR F 3 495 ? 128.229 163.147 102.812 1.00 39.07  ? 496 TYR F CD2 1 
ATOM   14418 C  CE1 . TYR F 3 495 ? 129.279 164.389 100.599 1.00 38.37  ? 496 TYR F CE1 1 
ATOM   14419 C  CE2 . TYR F 3 495 ? 129.334 162.618 102.197 1.00 37.81  ? 496 TYR F CE2 1 
ATOM   14420 C  CZ  . TYR F 3 495 ? 129.857 163.244 101.091 1.00 40.12  ? 496 TYR F CZ  1 
ATOM   14421 O  OH  . TYR F 3 495 ? 130.965 162.724 100.468 1.00 44.65  ? 496 TYR F OH  1 
ATOM   14422 N  N   . PRO F 3 496 ? 125.126 167.707 104.624 1.00 40.35  ? 497 PRO F N   1 
ATOM   14423 C  CA  . PRO F 3 496 ? 124.034 168.188 105.481 1.00 36.29  ? 497 PRO F CA  1 
ATOM   14424 C  C   . PRO F 3 496 ? 122.746 167.419 105.311 1.00 36.76  ? 497 PRO F C   1 
ATOM   14425 O  O   . PRO F 3 496 ? 121.922 167.408 106.232 1.00 42.47  ? 497 PRO F O   1 
ATOM   14426 C  CB  . PRO F 3 496 ? 123.868 169.651 105.048 1.00 42.77  ? 497 PRO F CB  1 
ATOM   14427 C  CG  . PRO F 3 496 ? 125.122 169.988 104.317 1.00 47.72  ? 497 PRO F CG  1 
ATOM   14428 C  CD  . PRO F 3 496 ? 125.559 168.729 103.663 1.00 43.44  ? 497 PRO F CD  1 
ATOM   14429 N  N   . THR F 3 497 ? 122.543 166.780 104.161 1.00 37.54  ? 498 THR F N   1 
ATOM   14430 C  CA  . THR F 3 497 ? 121.294 166.075 103.906 1.00 35.75  ? 498 THR F CA  1 
ATOM   14431 C  C   . THR F 3 497 ? 121.088 164.922 104.880 1.00 34.59  ? 498 THR F C   1 
ATOM   14432 O  O   . THR F 3 497 ? 119.949 164.598 105.225 1.00 35.70  ? 498 THR F O   1 
ATOM   14433 C  CB  . THR F 3 497 ? 121.282 165.579 102.460 1.00 37.91  ? 498 THR F CB  1 
ATOM   14434 O  OG1 . THR F 3 497 ? 121.426 166.696 101.577 1.00 36.50  ? 498 THR F OG1 1 
ATOM   14435 C  CG2 . THR F 3 497 ? 119.994 164.858 102.135 1.00 36.65  ? 498 THR F CG2 1 
ATOM   14436 N  N   . ASN F 3 498 ? 122.171 164.308 105.353 1.00 33.95  ? 499 ASN F N   1 
ATOM   14437 C  CA  . ASN F 3 498 ? 122.059 163.157 106.236 1.00 33.75  ? 499 ASN F CA  1 
ATOM   14438 C  C   . ASN F 3 498 ? 121.603 163.517 107.642 1.00 36.51  ? 499 ASN F C   1 
ATOM   14439 O  O   . ASN F 3 498 ? 121.319 162.610 108.428 1.00 40.98  ? 499 ASN F O   1 
ATOM   14440 C  CB  . ASN F 3 498 ? 123.399 162.431 106.318 1.00 34.87  ? 499 ASN F CB  1 
ATOM   14441 C  CG  . ASN F 3 498 ? 123.898 161.991 104.973 1.00 34.25  ? 499 ASN F CG  1 
ATOM   14442 O  OD1 . ASN F 3 498 ? 123.372 162.394 103.946 1.00 36.28  ? 499 ASN F OD1 1 
ATOM   14443 N  ND2 . ASN F 3 498 ? 124.924 161.162 104.969 1.00 34.50  ? 499 ASN F ND2 1 
ATOM   14444 N  N   . TYR F 3 499 ? 121.537 164.795 107.983 1.00 37.49  ? 500 TYR F N   1 
ATOM   14445 C  CA  . TYR F 3 499 ? 121.254 165.223 109.345 1.00 38.47  ? 500 TYR F CA  1 
ATOM   14446 C  C   . TYR F 3 499 ? 119.769 165.518 109.494 1.00 42.09  ? 500 TYR F C   1 
ATOM   14447 O  O   . TYR F 3 499 ? 119.192 166.251 108.687 1.00 44.66  ? 500 TYR F O   1 
ATOM   14448 C  CB  . TYR F 3 499 ? 122.093 166.447 109.707 1.00 40.27  ? 500 TYR F CB  1 
ATOM   14449 C  CG  . TYR F 3 499 ? 123.556 166.124 109.895 1.00 39.19  ? 500 TYR F CG  1 
ATOM   14450 C  CD1 . TYR F 3 499 ? 124.372 165.872 108.809 1.00 38.10  ? 500 TYR F CD1 1 
ATOM   14451 C  CD2 . TYR F 3 499 ? 124.115 166.059 111.156 1.00 39.64  ? 500 TYR F CD2 1 
ATOM   14452 C  CE1 . TYR F 3 499 ? 125.697 165.563 108.973 1.00 35.95  ? 500 TYR F CE1 1 
ATOM   14453 C  CE2 . TYR F 3 499 ? 125.442 165.755 111.328 1.00 40.09  ? 500 TYR F CE2 1 
ATOM   14454 C  CZ  . TYR F 3 499 ? 126.228 165.508 110.232 1.00 35.88  ? 500 TYR F CZ  1 
ATOM   14455 O  OH  . TYR F 3 499 ? 127.556 165.203 110.387 1.00 35.62  ? 500 TYR F OH  1 
ATOM   14456 N  N   . ASP F 3 500 ? 119.159 164.949 110.532 1.00 43.92  ? 501 ASP F N   1 
ATOM   14457 C  CA  . ASP F 3 500 ? 117.710 164.997 110.694 1.00 49.06  ? 501 ASP F CA  1 
ATOM   14458 C  C   . ASP F 3 500 ? 117.242 166.226 111.469 1.00 52.02  ? 501 ASP F C   1 
ATOM   14459 O  O   . ASP F 3 500 ? 116.426 167.005 110.969 1.00 56.77  ? 501 ASP F O   1 
ATOM   14460 C  CB  . ASP F 3 500 ? 117.222 163.721 111.382 1.00 50.85  ? 501 ASP F CB  1 
ATOM   14461 C  CG  . ASP F 3 500 ? 117.207 162.533 110.452 1.00 61.16  ? 501 ASP F CG  1 
ATOM   14462 O  OD1 . ASP F 3 500 ? 116.870 162.715 109.265 1.00 69.73  ? 501 ASP F OD1 1 
ATOM   14463 O  OD2 . ASP F 3 500 ? 117.535 161.417 110.902 1.00 64.38  ? 501 ASP F OD2 1 
ATOM   14464 N  N   . TYR F 3 501 ? 117.728 166.403 112.690 1.00 50.97  ? 502 TYR F N   1 
ATOM   14465 C  CA  . TYR F 3 501 ? 117.279 167.490 113.550 1.00 53.84  ? 502 TYR F CA  1 
ATOM   14466 C  C   . TYR F 3 501 ? 118.281 168.629 113.494 1.00 56.02  ? 502 TYR F C   1 
ATOM   14467 O  O   . TYR F 3 501 ? 119.486 168.405 113.642 1.00 59.70  ? 502 TYR F O   1 
ATOM   14468 C  CB  . TYR F 3 501 ? 117.098 167.013 114.989 1.00 59.91  ? 502 TYR F CB  1 
ATOM   14469 C  CG  . TYR F 3 501 ? 116.124 165.875 115.112 1.00 64.34  ? 502 TYR F CG  1 
ATOM   14470 C  CD1 . TYR F 3 501 ? 114.758 166.096 115.036 1.00 64.47  ? 502 TYR F CD1 1 
ATOM   14471 C  CD2 . TYR F 3 501 ? 116.569 164.579 115.293 1.00 63.44  ? 502 TYR F CD2 1 
ATOM   14472 C  CE1 . TYR F 3 501 ? 113.868 165.056 115.139 1.00 67.59  ? 502 TYR F CE1 1 
ATOM   14473 C  CE2 . TYR F 3 501 ? 115.687 163.537 115.396 1.00 67.02  ? 502 TYR F CE2 1 
ATOM   14474 C  CZ  . TYR F 3 501 ? 114.339 163.778 115.320 1.00 67.62  ? 502 TYR F CZ  1 
ATOM   14475 O  OH  . TYR F 3 501 ? 113.464 162.726 115.426 1.00 63.10  ? 502 TYR F OH  1 
ATOM   14476 N  N   . TRP F 3 502 ? 117.782 169.842 113.282 1.00 55.78  ? 503 TRP F N   1 
ATOM   14477 C  CA  . TRP F 3 502 ? 118.619 171.019 113.128 1.00 56.67  ? 503 TRP F CA  1 
ATOM   14478 C  C   . TRP F 3 502 ? 118.317 172.029 114.221 1.00 64.19  ? 503 TRP F C   1 
ATOM   14479 O  O   . TRP F 3 502 ? 117.190 172.122 114.712 1.00 72.45  ? 503 TRP F O   1 
ATOM   14480 C  CB  . TRP F 3 502 ? 118.417 171.672 111.762 1.00 55.42  ? 503 TRP F CB  1 
ATOM   14481 C  CG  . TRP F 3 502 ? 119.019 170.892 110.653 1.00 53.69  ? 503 TRP F CG  1 
ATOM   14482 C  CD1 . TRP F 3 502 ? 118.444 169.869 109.969 1.00 51.12  ? 503 TRP F CD1 1 
ATOM   14483 C  CD2 . TRP F 3 502 ? 120.324 171.064 110.097 1.00 54.34  ? 503 TRP F CD2 1 
ATOM   14484 N  NE1 . TRP F 3 502 ? 119.305 169.392 109.019 1.00 50.77  ? 503 TRP F NE1 1 
ATOM   14485 C  CE2 . TRP F 3 502 ? 120.469 170.110 109.077 1.00 53.70  ? 503 TRP F CE2 1 
ATOM   14486 C  CE3 . TRP F 3 502 ? 121.381 171.937 110.360 1.00 55.55  ? 503 TRP F CE3 1 
ATOM   14487 C  CZ2 . TRP F 3 502 ? 121.626 170.002 108.321 1.00 51.51  ? 503 TRP F CZ2 1 
ATOM   14488 C  CZ3 . TRP F 3 502 ? 122.528 171.827 109.611 1.00 54.16  ? 503 TRP F CZ3 1 
ATOM   14489 C  CH2 . TRP F 3 502 ? 122.643 170.868 108.604 1.00 52.48  ? 503 TRP F CH2 1 
ATOM   14490 N  N   . GLY F 3 503 ? 119.338 172.787 114.592 1.00 69.31  ? 504 GLY F N   1 
ATOM   14491 C  CA  . GLY F 3 503 ? 119.219 173.809 115.607 1.00 78.09  ? 504 GLY F CA  1 
ATOM   14492 C  C   . GLY F 3 503 ? 118.705 175.115 115.043 1.00 84.06  ? 504 GLY F C   1 
ATOM   14493 O  O   . GLY F 3 503 ? 118.048 175.162 114.001 1.00 81.90  ? 504 GLY F O   1 
ATOM   14494 N  N   . GLN F 3 504 ? 119.010 176.192 115.754 1.00 93.68  ? 505 GLN F N   1 
ATOM   14495 C  CA  . GLN F 3 504 ? 118.554 177.527 115.402 1.00 97.18  ? 505 GLN F CA  1 
ATOM   14496 C  C   . GLN F 3 504 ? 119.721 178.344 114.872 1.00 94.00  ? 505 GLN F C   1 
ATOM   14497 O  O   . GLN F 3 504 ? 120.824 178.302 115.425 1.00 91.04  ? 505 GLN F O   1 
ATOM   14498 C  CB  . GLN F 3 504 ? 117.933 178.222 116.613 1.00 95.84  ? 505 GLN F CB  1 
ATOM   14499 C  CG  . GLN F 3 504 ? 116.923 177.363 117.350 1.00 96.91  ? 505 GLN F CG  1 
ATOM   14500 C  CD  . GLN F 3 504 ? 116.565 177.927 118.706 1.00 105.64 ? 505 GLN F CD  1 
ATOM   14501 O  OE1 . GLN F 3 504 ? 116.316 177.181 119.652 1.00 109.99 ? 505 GLN F OE1 1 
ATOM   14502 N  NE2 . GLN F 3 504 ? 116.538 179.252 118.812 1.00 103.94 ? 505 GLN F NE2 1 
ATOM   14503 N  N   . GLY F 3 505 ? 119.475 179.080 113.796 1.00 90.91  ? 506 GLY F N   1 
ATOM   14504 C  CA  . GLY F 3 505 ? 120.525 179.862 113.181 1.00 92.28  ? 506 GLY F CA  1 
ATOM   14505 C  C   . GLY F 3 505 ? 121.150 180.867 114.125 1.00 99.56  ? 506 GLY F C   1 
ATOM   14506 O  O   . GLY F 3 505 ? 120.462 181.738 114.664 1.00 103.94 ? 506 GLY F O   1 
ATOM   14507 N  N   . THR F 3 506 ? 122.458 180.754 114.329 1.00 97.56  ? 507 THR F N   1 
ATOM   14508 C  CA  . THR F 3 506 ? 123.206 181.647 115.201 1.00 94.86  ? 507 THR F CA  1 
ATOM   14509 C  C   . THR F 3 506 ? 124.129 182.505 114.352 1.00 95.81  ? 507 THR F C   1 
ATOM   14510 O  O   . THR F 3 506 ? 124.852 181.986 113.496 1.00 95.61  ? 507 THR F O   1 
ATOM   14511 C  CB  . THR F 3 506 ? 124.015 180.861 116.233 1.00 91.32  ? 507 THR F CB  1 
ATOM   14512 O  OG1 . THR F 3 506 ? 123.127 180.117 117.073 1.00 88.87  ? 507 THR F OG1 1 
ATOM   14513 C  CG2 . THR F 3 506 ? 124.836 181.802 117.089 1.00 91.66  ? 507 THR F CG2 1 
ATOM   14514 N  N   . GLN F 3 507 ? 124.096 183.812 114.581 1.00 98.30  ? 508 GLN F N   1 
ATOM   14515 C  CA  . GLN F 3 507 ? 124.901 184.745 113.811 1.00 99.01  ? 508 GLN F CA  1 
ATOM   14516 C  C   . GLN F 3 507 ? 126.265 184.919 114.464 1.00 99.69  ? 508 GLN F C   1 
ATOM   14517 O  O   . GLN F 3 507 ? 126.357 185.178 115.668 1.00 98.27  ? 508 GLN F O   1 
ATOM   14518 C  CB  . GLN F 3 507 ? 124.195 186.094 113.692 1.00 97.76  ? 508 GLN F CB  1 
ATOM   14519 C  CG  . GLN F 3 507 ? 124.943 187.101 112.843 1.00 103.31 ? 508 GLN F CG  1 
ATOM   14520 C  CD  . GLN F 3 507 ? 125.004 186.704 111.385 1.00 104.24 ? 508 GLN F CD  1 
ATOM   14521 O  OE1 . GLN F 3 507 ? 124.173 185.934 110.903 1.00 101.53 ? 508 GLN F OE1 1 
ATOM   14522 N  NE2 . GLN F 3 507 ? 125.991 187.228 110.671 1.00 105.79 ? 508 GLN F NE2 1 
ATOM   14523 N  N   . VAL F 3 508 ? 127.320 184.759 113.670 1.00 99.29  ? 509 VAL F N   1 
ATOM   14524 C  CA  . VAL F 3 508 ? 128.691 184.959 114.120 1.00 98.45  ? 509 VAL F CA  1 
ATOM   14525 C  C   . VAL F 3 508 ? 129.390 185.875 113.127 1.00 100.32 ? 509 VAL F C   1 
ATOM   14526 O  O   . VAL F 3 508 ? 129.347 185.632 111.917 1.00 99.68  ? 509 VAL F O   1 
ATOM   14527 C  CB  . VAL F 3 508 ? 129.449 183.627 114.257 1.00 94.49  ? 509 VAL F CB  1 
ATOM   14528 C  CG1 . VAL F 3 508 ? 130.903 183.881 114.582 1.00 93.17  ? 509 VAL F CG1 1 
ATOM   14529 C  CG2 . VAL F 3 508 ? 128.813 182.777 115.332 1.00 90.74  ? 509 VAL F CG2 1 
ATOM   14530 N  N   . THR F 3 509 ? 130.029 186.923 113.638 1.00 103.97 ? 510 THR F N   1 
ATOM   14531 C  CA  . THR F 3 509 ? 130.745 187.873 112.794 1.00 109.17 ? 510 THR F CA  1 
ATOM   14532 C  C   . THR F 3 509 ? 132.253 187.653 112.876 1.00 109.24 ? 510 THR F C   1 
ATOM   14533 O  O   . THR F 3 509 ? 133.041 188.458 112.377 1.00 106.21 ? 510 THR F O   1 
ATOM   14534 C  CB  . THR F 3 509 ? 130.425 189.327 113.185 1.00 112.61 ? 510 THR F CB  1 
ATOM   14535 O  OG1 . THR F 3 509 ? 130.997 190.220 112.222 1.00 116.15 ? 510 THR F OG1 1 
ATOM   14536 C  CG2 . THR F 3 509 ? 130.993 189.644 114.559 1.00 105.21 ? 510 THR F CG2 1 
HETATM 14537 C  C1  . NAG G 4 .   ? 127.947 118.393 95.344  1.00 53.95  ? 1   NAG a C1  1 
HETATM 14538 C  C2  . NAG G 4 .   ? 128.311 119.819 94.942  1.00 58.00  ? 1   NAG a C2  1 
HETATM 14539 C  C3  . NAG G 4 .   ? 128.266 119.950 93.423  1.00 60.21  ? 1   NAG a C3  1 
HETATM 14540 C  C4  . NAG G 4 .   ? 129.180 118.908 92.792  1.00 63.01  ? 1   NAG a C4  1 
HETATM 14541 C  C5  . NAG G 4 .   ? 128.863 117.507 93.312  1.00 59.97  ? 1   NAG a C5  1 
HETATM 14542 C  C6  . NAG G 4 .   ? 129.886 116.488 92.868  1.00 60.68  ? 1   NAG a C6  1 
HETATM 14543 C  C7  . NAG G 4 .   ? 127.847 121.621 96.536  1.00 61.46  ? 1   NAG a C7  1 
HETATM 14544 C  C8  . NAG G 4 .   ? 126.818 122.568 97.078  1.00 56.38  ? 1   NAG a C8  1 
HETATM 14545 N  N2  . NAG G 4 .   ? 127.433 120.791 95.572  1.00 61.13  ? 1   NAG a N2  1 
HETATM 14546 O  O3  . NAG G 4 .   ? 128.686 121.256 93.044  1.00 63.09  ? 1   NAG a O3  1 
HETATM 14547 O  O4  . NAG G 4 .   ? 129.011 118.913 91.378  1.00 64.23  ? 1   NAG a O4  1 
HETATM 14548 O  O5  . NAG G 4 .   ? 128.871 117.484 94.750  1.00 59.27  ? 1   NAG a O5  1 
HETATM 14549 O  O6  . NAG G 4 .   ? 129.789 115.285 93.614  1.00 55.49  ? 1   NAG a O6  1 
HETATM 14550 O  O7  . NAG G 4 .   ? 129.001 121.606 96.954  1.00 62.41  ? 1   NAG a O7  1 
HETATM 14551 C  C1  . NAG G 4 .   ? 130.202 119.407 90.735  1.00 99.91  ? 2   NAG a C1  1 
HETATM 14552 C  C2  . NAG G 4 .   ? 130.161 118.976 89.271  1.00 100.65 ? 2   NAG a C2  1 
HETATM 14553 C  C3  . NAG G 4 .   ? 131.384 119.512 88.532  1.00 94.33  ? 2   NAG a C3  1 
HETATM 14554 C  C4  . NAG G 4 .   ? 131.463 121.022 88.701  1.00 95.65  ? 2   NAG a C4  1 
HETATM 14555 C  C5  . NAG G 4 .   ? 131.459 121.376 90.185  1.00 98.29  ? 2   NAG a C5  1 
HETATM 14556 C  C6  . NAG G 4 .   ? 131.432 122.866 90.440  1.00 102.17 ? 2   NAG a C6  1 
HETATM 14557 C  C7  . NAG G 4 .   ? 128.951 116.881 88.870  1.00 102.85 ? 2   NAG a C7  1 
HETATM 14558 C  C8  . NAG G 4 .   ? 129.050 115.386 88.789  1.00 93.40  ? 2   NAG a C8  1 
HETATM 14559 N  N2  . NAG G 4 .   ? 130.085 117.529 89.158  1.00 99.53  ? 2   NAG a N2  1 
HETATM 14560 O  O3  . NAG G 4 .   ? 131.304 119.175 87.152  1.00 85.56  ? 2   NAG a O3  1 
HETATM 14561 O  O4  . NAG G 4 .   ? 132.662 121.504 88.104  1.00 90.58  ? 2   NAG a O4  1 
HETATM 14562 O  O5  . NAG G 4 .   ? 130.287 120.830 90.813  1.00 103.41 ? 2   NAG a O5  1 
HETATM 14563 O  O6  . NAG G 4 .   ? 131.454 123.158 91.829  1.00 111.34 ? 2   NAG a O6  1 
HETATM 14564 O  O7  . NAG G 4 .   ? 127.894 117.475 88.681  1.00 108.15 ? 2   NAG a O7  1 
HETATM 14565 C  C1  . BMA G 4 .   ? 132.360 122.482 87.089  1.00 4.75   ? 3   BMA a C1  1 
HETATM 14566 C  C2  . BMA G 4 .   ? 133.524 123.463 87.063  1.00 4.75   ? 3   BMA a C2  1 
HETATM 14567 C  C3  . BMA G 4 .   ? 133.297 124.520 85.992  1.00 4.75   ? 3   BMA a C3  1 
HETATM 14568 C  C4  . BMA G 4 .   ? 133.032 123.862 84.646  1.00 4.75   ? 3   BMA a C4  1 
HETATM 14569 C  C5  . BMA G 4 .   ? 131.891 122.857 84.772  1.00 4.75   ? 3   BMA a C5  1 
HETATM 14570 C  C6  . BMA G 4 .   ? 131.639 122.077 83.500  1.00 4.75   ? 3   BMA a C6  1 
HETATM 14571 O  O2  . BMA G 4 .   ? 134.732 122.755 86.808  1.00 4.75   ? 3   BMA a O2  1 
HETATM 14572 O  O3  . BMA G 4 .   ? 134.433 125.374 85.904  1.00 4.75   ? 3   BMA a O3  1 
HETATM 14573 O  O4  . BMA G 4 .   ? 132.683 124.853 83.685  1.00 4.75   ? 3   BMA a O4  1 
HETATM 14574 O  O5  . BMA G 4 .   ? 132.200 121.896 85.795  1.00 4.75   ? 3   BMA a O5  1 
HETATM 14575 O  O6  . BMA G 4 .   ? 132.803 121.384 83.065  1.00 4.75   ? 3   BMA a O6  1 
HETATM 14576 C  C1  . MAN G 4 .   ? 134.367 126.344 86.966  1.00 120.93 ? 4   MAN a C1  1 
HETATM 14577 C  C2  . MAN G 4 .   ? 134.031 127.702 86.364  1.00 129.18 ? 4   MAN a C2  1 
HETATM 14578 C  C3  . MAN G 4 .   ? 135.146 128.153 85.432  1.00 127.97 ? 4   MAN a C3  1 
HETATM 14579 C  C4  . MAN G 4 .   ? 136.492 128.108 86.141  1.00 127.50 ? 4   MAN a C4  1 
HETATM 14580 C  C5  . MAN G 4 .   ? 136.712 126.740 86.780  1.00 119.38 ? 4   MAN a C5  1 
HETATM 14581 C  C6  . MAN G 4 .   ? 137.959 126.682 87.630  1.00 111.14 ? 4   MAN a C6  1 
HETATM 14582 O  O2  . MAN G 4 .   ? 133.845 128.657 87.404  1.00 129.79 ? 4   MAN a O2  1 
HETATM 14583 O  O3  . MAN G 4 .   ? 134.885 129.477 84.977  1.00 120.17 ? 4   MAN a O3  1 
HETATM 14584 O  O4  . MAN G 4 .   ? 137.536 128.355 85.205  1.00 120.03 ? 4   MAN a O4  1 
HETATM 14585 O  O5  . MAN G 4 .   ? 135.615 126.425 87.650  1.00 123.06 ? 4   MAN a O5  1 
HETATM 14586 O  O6  . MAN G 4 .   ? 138.104 125.406 88.232  1.00 109.22 ? 4   MAN a O6  1 
HETATM 14587 C  C1  . MAN G 4 .   ? 132.672 121.093 81.655  1.00 118.28 ? 5   MAN a C1  1 
HETATM 14588 C  C2  . MAN G 4 .   ? 133.774 120.121 81.240  1.00 124.42 ? 5   MAN a C2  1 
HETATM 14589 C  C3  . MAN G 4 .   ? 135.142 120.781 81.355  1.00 125.09 ? 5   MAN a C3  1 
HETATM 14590 C  C4  . MAN G 4 .   ? 135.169 122.094 80.587  1.00 127.88 ? 5   MAN a C4  1 
HETATM 14591 C  C5  . MAN G 4 .   ? 134.014 122.985 81.036  1.00 125.88 ? 5   MAN a C5  1 
HETATM 14592 C  C6  . MAN G 4 .   ? 133.904 124.262 80.236  1.00 119.10 ? 5   MAN a C6  1 
HETATM 14593 O  O2  . MAN G 4 .   ? 133.551 119.690 79.902  1.00 125.28 ? 5   MAN a O2  1 
HETATM 14594 O  O3  . MAN G 4 .   ? 136.153 119.913 80.855  1.00 111.23 ? 5   MAN a O3  1 
HETATM 14595 O  O4  . MAN G 4 .   ? 136.402 122.765 80.823  1.00 121.72 ? 5   MAN a O4  1 
HETATM 14596 O  O5  . MAN G 4 .   ? 132.769 122.287 80.872  1.00 121.91 ? 5   MAN a O5  1 
HETATM 14597 O  O6  . MAN G 4 .   ? 133.625 123.988 78.871  1.00 119.46 ? 5   MAN a O6  1 
HETATM 14598 C  C1  . NAG H 4 .   ? 126.999 97.220  117.118 1.00 53.31  ? 1   NAG b C1  1 
HETATM 14599 C  C2  . NAG H 4 .   ? 127.768 95.907  116.990 1.00 49.99  ? 1   NAG b C2  1 
HETATM 14600 C  C3  . NAG H 4 .   ? 127.480 95.254  115.640 1.00 53.60  ? 1   NAG b C3  1 
HETATM 14601 C  C4  . NAG H 4 .   ? 125.981 95.124  115.409 1.00 56.10  ? 1   NAG b C4  1 
HETATM 14602 C  C5  . NAG H 4 .   ? 125.305 96.476  115.607 1.00 56.05  ? 1   NAG b C5  1 
HETATM 14603 C  C6  . NAG H 4 .   ? 123.800 96.397  115.517 1.00 56.40  ? 1   NAG b C6  1 
HETATM 14604 C  C7  . NAG H 4 .   ? 130.037 95.203  117.600 1.00 53.97  ? 1   NAG b C7  1 
HETATM 14605 C  C8  . NAG H 4 .   ? 131.475 95.615  117.713 1.00 49.39  ? 1   NAG b C8  1 
HETATM 14606 N  N2  . NAG H 4 .   ? 129.194 96.137  117.152 1.00 49.71  ? 1   NAG b N2  1 
HETATM 14607 O  O3  . NAG H 4 .   ? 128.081 93.966  115.597 1.00 55.13  ? 1   NAG b O3  1 
HETATM 14608 O  O4  . NAG H 4 .   ? 125.736 94.724  114.066 1.00 66.89  ? 1   NAG b O4  1 
HETATM 14609 O  O5  . NAG H 4 .   ? 125.609 96.982  116.913 1.00 62.18  ? 1   NAG b O5  1 
HETATM 14610 O  O6  . NAG H 4 .   ? 123.203 97.662  115.755 1.00 62.10  ? 1   NAG b O6  1 
HETATM 14611 O  O7  . NAG H 4 .   ? 129.659 94.075  117.894 1.00 62.42  ? 1   NAG b O7  1 
HETATM 14612 C  C1  . NAG H 4 .   ? 125.307 93.364  113.957 1.00 65.63  ? 2   NAG b C1  1 
HETATM 14613 C  C2  . NAG H 4 .   ? 124.355 93.270  112.768 1.00 65.51  ? 2   NAG b C2  1 
HETATM 14614 C  C3  . NAG H 4 .   ? 123.945 91.822  112.528 1.00 67.47  ? 2   NAG b C3  1 
HETATM 14615 C  C4  . NAG H 4 .   ? 125.172 90.935  112.391 1.00 68.83  ? 2   NAG b C4  1 
HETATM 14616 C  C5  . NAG H 4 .   ? 126.073 91.119  113.608 1.00 69.23  ? 2   NAG b C5  1 
HETATM 14617 C  C6  . NAG H 4 .   ? 127.373 90.358  113.501 1.00 69.60  ? 2   NAG b C6  1 
HETATM 14618 C  C7  . NAG H 4 .   ? 122.922 95.194  112.251 1.00 62.69  ? 2   NAG b C7  1 
HETATM 14619 C  C8  . NAG H 4 .   ? 121.659 95.927  112.595 1.00 54.25  ? 2   NAG b C8  1 
HETATM 14620 N  N2  . NAG H 4 .   ? 123.182 94.102  112.976 1.00 66.41  ? 2   NAG b N2  1 
HETATM 14621 O  O3  . NAG H 4 .   ? 123.163 91.754  111.341 1.00 71.78  ? 2   NAG b O3  1 
HETATM 14622 O  O4  . NAG H 4 .   ? 124.755 89.576  112.346 1.00 77.50  ? 2   NAG b O4  1 
HETATM 14623 O  O5  . NAG H 4 .   ? 126.421 92.503  113.749 1.00 70.35  ? 2   NAG b O5  1 
HETATM 14624 O  O6  . NAG H 4 .   ? 128.157 90.520  114.672 1.00 70.01  ? 2   NAG b O6  1 
HETATM 14625 O  O7  . NAG H 4 .   ? 123.676 95.579  111.364 1.00 65.58  ? 2   NAG b O7  1 
HETATM 14626 C  C1  . BMA H 4 .   ? 125.215 88.924  111.148 1.00 85.71  ? 3   BMA b C1  1 
HETATM 14627 C  C2  . BMA H 4 .   ? 124.890 87.444  111.297 1.00 91.85  ? 3   BMA b C2  1 
HETATM 14628 C  C3  . BMA H 4 .   ? 125.337 86.683  110.060 1.00 94.45  ? 3   BMA b C3  1 
HETATM 14629 C  C4  . BMA H 4 .   ? 124.737 87.305  108.809 1.00 93.45  ? 3   BMA b C4  1 
HETATM 14630 C  C5  . BMA H 4 .   ? 125.043 88.799  108.766 1.00 91.74  ? 3   BMA b C5  1 
HETATM 14631 C  C6  . BMA H 4 .   ? 124.361 89.503  107.616 1.00 88.67  ? 3   BMA b C6  1 
HETATM 14632 O  O2  . BMA H 4 .   ? 123.489 87.277  111.487 1.00 85.41  ? 3   BMA b O2  1 
HETATM 14633 O  O3  . BMA H 4 .   ? 124.943 85.320  110.161 1.00 90.32  ? 3   BMA b O3  1 
HETATM 14634 O  O4  . BMA H 4 .   ? 125.285 86.682  107.652 1.00 91.57  ? 3   BMA b O4  1 
HETATM 14635 O  O5  . BMA H 4 .   ? 124.582 89.429  109.972 1.00 89.49  ? 3   BMA b O5  1 
HETATM 14636 O  O6  . BMA H 4 .   ? 122.977 89.191  107.564 1.00 93.42  ? 3   BMA b O6  1 
HETATM 14637 C  C1  . MAN H 4 .   ? 126.104 84.537  110.486 1.00 36.64  ? 4   MAN b C1  1 
HETATM 14638 C  C2  . MAN H 4 .   ? 125.865 83.118  109.993 1.00 36.64  ? 4   MAN b C2  1 
HETATM 14639 C  C3  . MAN H 4 .   ? 124.696 82.497  110.744 1.00 36.64  ? 4   MAN b C3  1 
HETATM 14640 C  C4  . MAN H 4 .   ? 124.927 82.583  112.246 1.00 36.64  ? 4   MAN b C4  1 
HETATM 14641 C  C5  . MAN H 4 .   ? 125.216 84.026  112.646 1.00 36.64  ? 4   MAN b C5  1 
HETATM 14642 C  C6  . MAN H 4 .   ? 125.571 84.179  114.107 1.00 36.64  ? 4   MAN b C6  1 
HETATM 14643 O  O2  . MAN H 4 .   ? 127.042 82.342  110.188 1.00 36.64  ? 4   MAN b O2  1 
HETATM 14644 O  O3  . MAN H 4 .   ? 124.524 81.141  110.347 1.00 36.64  ? 4   MAN b O3  1 
HETATM 14645 O  O4  . MAN H 4 .   ? 123.770 82.134  112.943 1.00 36.64  ? 4   MAN b O4  1 
HETATM 14646 O  O5  . MAN H 4 .   ? 126.336 84.520  111.895 1.00 36.64  ? 4   MAN b O5  1 
HETATM 14647 O  O6  . MAN H 4 .   ? 125.764 85.543  114.454 1.00 36.64  ? 4   MAN b O6  1 
HETATM 14648 C  C1  . MAN H 4 .   ? 122.535 89.344  106.200 1.00 95.18  ? 5   MAN b C1  1 
HETATM 14649 C  C2  . MAN H 4 .   ? 121.031 89.607  106.215 1.00 100.72 ? 5   MAN b C2  1 
HETATM 14650 C  C3  . MAN H 4 .   ? 120.281 88.380  106.714 1.00 102.51 ? 5   MAN b C3  1 
HETATM 14651 C  C4  . MAN H 4 .   ? 120.664 87.159  105.892 1.00 107.49 ? 5   MAN b C4  1 
HETATM 14652 C  C5  . MAN H 4 .   ? 122.180 86.982  105.908 1.00 106.37 ? 5   MAN b C5  1 
HETATM 14653 C  C6  . MAN H 4 .   ? 122.648 85.849  105.024 1.00 101.90 ? 5   MAN b C6  1 
HETATM 14654 O  O2  . MAN H 4 .   ? 120.595 89.951  104.904 1.00 96.94  ? 5   MAN b O2  1 
HETATM 14655 O  O3  . MAN H 4 .   ? 118.877 88.598  106.640 1.00 95.68  ? 5   MAN b O3  1 
HETATM 14656 O  O4  . MAN H 4 .   ? 120.050 85.993  106.430 1.00 107.78 ? 5   MAN b O4  1 
HETATM 14657 O  O5  . MAN H 4 .   ? 122.814 88.176  105.420 1.00 99.66  ? 5   MAN b O5  1 
HETATM 14658 O  O6  . MAN H 4 .   ? 124.060 85.705  105.075 1.00 103.69 ? 5   MAN b O6  1 
HETATM 14659 C  C1  . NAG I 5 .   ? 148.631 97.930  87.699  1.00 73.37  ? 1   NAG G C1  1 
HETATM 14660 C  C2  . NAG I 5 .   ? 150.036 97.431  88.031  1.00 76.74  ? 1   NAG G C2  1 
HETATM 14661 C  C3  . NAG I 5 .   ? 150.037 95.911  88.162  1.00 81.76  ? 1   NAG G C3  1 
HETATM 14662 C  C4  . NAG I 5 .   ? 148.983 95.466  89.165  1.00 85.04  ? 1   NAG G C4  1 
HETATM 14663 C  C5  . NAG I 5 .   ? 147.624 96.042  88.782  1.00 83.39  ? 1   NAG G C5  1 
HETATM 14664 C  C6  . NAG I 5 .   ? 146.551 95.744  89.802  1.00 83.03  ? 1   NAG G C6  1 
HETATM 14665 C  C7  . NAG I 5 .   ? 152.076 98.577  87.295  1.00 80.28  ? 1   NAG G C7  1 
HETATM 14666 C  C8  . NAG I 5 .   ? 152.952 98.923  86.128  1.00 76.87  ? 1   NAG G C8  1 
HETATM 14667 N  N2  . NAG I 5 .   ? 150.986 97.856  87.016  1.00 77.24  ? 1   NAG G N2  1 
HETATM 14668 O  O3  . NAG I 5 .   ? 151.324 95.481  88.592  1.00 86.07  ? 1   NAG G O3  1 
HETATM 14669 O  O4  . NAG I 5 .   ? 148.892 94.045  89.175  1.00 79.80  ? 1   NAG G O4  1 
HETATM 14670 O  O5  . NAG I 5 .   ? 147.714 97.472  88.692  1.00 79.47  ? 1   NAG G O5  1 
HETATM 14671 O  O6  . NAG I 5 .   ? 146.895 96.277  91.073  1.00 82.00  ? 1   NAG G O6  1 
HETATM 14672 O  O7  . NAG I 5 .   ? 152.339 98.943  88.437  1.00 79.29  ? 1   NAG G O7  1 
HETATM 14673 C  C1  . NAG I 5 .   ? 149.331 93.537  90.451  1.00 45.12  ? 2   NAG G C1  1 
HETATM 14674 C  C2  . NAG I 5 .   ? 148.782 92.121  90.612  1.00 45.12  ? 2   NAG G C2  1 
HETATM 14675 C  C3  . NAG I 5 .   ? 149.251 91.525  91.935  1.00 45.12  ? 2   NAG G C3  1 
HETATM 14676 C  C4  . NAG I 5 .   ? 150.770 91.582  92.011  1.00 45.12  ? 2   NAG G C4  1 
HETATM 14677 C  C5  . NAG I 5 .   ? 151.246 93.016  91.798  1.00 45.12  ? 2   NAG G C5  1 
HETATM 14678 C  C6  . NAG I 5 .   ? 152.752 93.135  91.754  1.00 45.12  ? 2   NAG G C6  1 
HETATM 14679 C  C7  . NAG I 5 .   ? 146.665 91.792  89.418  1.00 45.12  ? 2   NAG G C7  1 
HETATM 14680 C  C8  . NAG I 5 .   ? 145.168 91.832  89.512  1.00 45.12  ? 2   NAG G C8  1 
HETATM 14681 N  N2  . NAG I 5 .   ? 147.331 92.113  90.532  1.00 45.12  ? 2   NAG G N2  1 
HETATM 14682 O  O3  . NAG I 5 .   ? 148.807 90.176  92.032  1.00 45.12  ? 2   NAG G O3  1 
HETATM 14683 O  O4  . NAG I 5 .   ? 151.216 91.119  93.281  1.00 45.12  ? 2   NAG G O4  1 
HETATM 14684 O  O5  . NAG I 5 .   ? 150.757 93.510  90.540  1.00 45.12  ? 2   NAG G O5  1 
HETATM 14685 O  O6  . NAG I 5 .   ? 153.340 92.709  92.975  1.00 45.12  ? 2   NAG G O6  1 
HETATM 14686 O  O7  . NAG I 5 .   ? 147.244 91.486  88.379  1.00 45.12  ? 2   NAG G O7  1 
HETATM 14687 C  C1  . NAG J 4 .   ? 150.889 149.753 115.505 1.00 49.42  ? 1   NAG c C1  1 
HETATM 14688 C  C2  . NAG J 4 .   ? 150.975 151.268 115.336 1.00 46.89  ? 1   NAG c C2  1 
HETATM 14689 C  C3  . NAG J 4 .   ? 151.616 151.616 113.994 1.00 49.74  ? 1   NAG c C3  1 
HETATM 14690 C  C4  . NAG J 4 .   ? 152.930 150.876 113.788 1.00 52.93  ? 1   NAG c C4  1 
HETATM 14691 C  C5  . NAG J 4 .   ? 152.747 149.386 114.049 1.00 50.82  ? 1   NAG c C5  1 
HETATM 14692 C  C6  . NAG J 4 .   ? 154.052 148.628 114.021 1.00 51.76  ? 1   NAG c C6  1 
HETATM 14693 C  C7  . NAG J 4 .   ? 149.421 153.045 116.020 1.00 51.68  ? 1   NAG c C7  1 
HETATM 14694 C  C8  . NAG J 4 .   ? 147.999 153.520 116.003 1.00 44.70  ? 1   NAG c C8  1 
HETATM 14695 N  N2  . NAG J 4 .   ? 149.653 151.866 115.432 1.00 47.09  ? 1   NAG c N2  1 
HETATM 14696 O  O3  . NAG J 4 .   ? 151.851 153.018 113.936 1.00 48.89  ? 1   NAG c O3  1 
HETATM 14697 O  O4  . NAG J 4 .   ? 153.319 151.000 112.424 1.00 59.73  ? 1   NAG c O4  1 
HETATM 14698 O  O5  . NAG J 4 .   ? 152.185 149.182 115.351 1.00 53.90  ? 1   NAG c O5  1 
HETATM 14699 O  O6  . NAG J 4 .   ? 153.835 147.227 114.073 1.00 60.01  ? 1   NAG c O6  1 
HETATM 14700 O  O7  . NAG J 4 .   ? 150.316 153.694 116.549 1.00 59.87  ? 1   NAG c O7  1 
HETATM 14701 C  C1  . NAG J 4 .   ? 154.474 151.824 112.202 1.00 58.68  ? 2   NAG c C1  1 
HETATM 14702 C  C2  . NAG J 4 .   ? 155.161 151.335 110.930 1.00 56.89  ? 2   NAG c C2  1 
HETATM 14703 C  C3  . NAG J 4 .   ? 156.358 152.221 110.604 1.00 62.64  ? 2   NAG c C3  1 
HETATM 14704 C  C4  . NAG J 4 .   ? 155.924 153.675 110.524 1.00 66.73  ? 2   NAG c C4  1 
HETATM 14705 C  C5  . NAG J 4 .   ? 155.214 154.074 111.813 1.00 64.00  ? 2   NAG c C5  1 
HETATM 14706 C  C6  . NAG J 4 .   ? 154.652 155.476 111.759 1.00 63.82  ? 2   NAG c C6  1 
HETATM 14707 C  C7  . NAG J 4 .   ? 155.060 148.962 110.321 1.00 56.17  ? 2   NAG c C7  1 
HETATM 14708 C  C8  . NAG J 4 .   ? 155.621 147.592 110.565 1.00 51.43  ? 2   NAG c C8  1 
HETATM 14709 N  N2  . NAG J 4 .   ? 155.577 149.948 111.058 1.00 56.19  ? 2   NAG c N2  1 
HETATM 14710 O  O3  . NAG J 4 .   ? 156.929 151.820 109.364 1.00 66.11  ? 2   NAG c O3  1 
HETATM 14711 O  O4  . NAG J 4 .   ? 157.079 154.491 110.375 1.00 78.60  ? 2   NAG c O4  1 
HETATM 14712 O  O5  . NAG J 4 .   ? 154.105 153.193 112.051 1.00 63.20  ? 2   NAG c O5  1 
HETATM 14713 O  O6  . NAG J 4 .   ? 154.185 155.902 113.029 1.00 64.11  ? 2   NAG c O6  1 
HETATM 14714 O  O7  . NAG J 4 .   ? 154.172 149.162 109.499 1.00 61.63  ? 2   NAG c O7  1 
HETATM 14715 C  C1  . BMA J 4 .   ? 157.025 155.208 109.134 1.00 82.99  ? 3   BMA c C1  1 
HETATM 14716 C  C2  . BMA J 4 .   ? 158.039 156.337 109.231 1.00 86.87  ? 3   BMA c C2  1 
HETATM 14717 C  C3  . BMA J 4 .   ? 158.109 157.107 107.921 1.00 90.76  ? 3   BMA c C3  1 
HETATM 14718 C  C4  . BMA J 4 .   ? 158.354 156.159 106.757 1.00 93.46  ? 3   BMA c C4  1 
HETATM 14719 C  C5  . BMA J 4 .   ? 157.314 155.043 106.767 1.00 89.10  ? 3   BMA c C5  1 
HETATM 14720 C  C6  . BMA J 4 .   ? 157.562 153.997 105.707 1.00 89.85  ? 3   BMA c C6  1 
HETATM 14721 O  O2  . BMA J 4 .   ? 159.318 155.800 109.551 1.00 84.48  ? 3   BMA c O2  1 
HETATM 14722 O  O3  . BMA J 4 .   ? 159.156 158.068 107.990 1.00 90.28  ? 3   BMA c O3  1 
HETATM 14723 O  O4  . BMA J 4 .   ? 158.261 156.867 105.526 1.00 93.91  ? 3   BMA c O4  1 
HETATM 14724 O  O5  . BMA J 4 .   ? 157.348 154.364 108.032 1.00 86.86  ? 3   BMA c O5  1 
HETATM 14725 O  O6  . BMA J 4 .   ? 158.814 153.356 105.903 1.00 96.20  ? 3   BMA c O6  1 
HETATM 14726 C  C1  . MAN J 4 .   ? 158.592 159.387 107.884 1.00 23.56  ? 4   MAN c C1  1 
HETATM 14727 C  C2  . MAN J 4 .   ? 159.687 160.339 107.417 1.00 23.56  ? 4   MAN c C2  1 
HETATM 14728 C  C3  . MAN J 4 .   ? 160.780 160.448 108.471 1.00 23.56  ? 4   MAN c C3  1 
HETATM 14729 C  C4  . MAN J 4 .   ? 160.185 160.817 109.822 1.00 23.56  ? 4   MAN c C4  1 
HETATM 14730 C  C5  . MAN J 4 .   ? 159.068 159.842 110.185 1.00 23.56  ? 4   MAN c C5  1 
HETATM 14731 C  C6  . MAN J 4 .   ? 158.346 160.216 111.459 1.00 23.56  ? 4   MAN c C6  1 
HETATM 14732 O  O2  . MAN J 4 .   ? 159.125 161.622 107.160 1.00 23.56  ? 4   MAN c O2  1 
HETATM 14733 O  O3  . MAN J 4 .   ? 161.733 161.430 108.079 1.00 23.56  ? 4   MAN c O3  1 
HETATM 14734 O  O4  . MAN J 4 .   ? 161.190 160.776 110.830 1.00 23.56  ? 4   MAN c O4  1 
HETATM 14735 O  O5  . MAN J 4 .   ? 158.080 159.827 109.142 1.00 23.56  ? 4   MAN c O5  1 
HETATM 14736 O  O6  . MAN J 4 .   ? 157.300 159.297 111.745 1.00 23.56  ? 4   MAN c O6  1 
HETATM 14737 C  C1  . MAN J 4 .   ? 159.007 152.403 104.841 1.00 101.50 ? 5   MAN c C1  1 
HETATM 14738 C  C2  . MAN J 4 .   ? 160.038 151.376 105.303 1.00 104.25 ? 5   MAN c C2  1 
HETATM 14739 C  C3  . MAN J 4 .   ? 161.402 152.032 105.477 1.00 108.10 ? 5   MAN c C3  1 
HETATM 14740 C  C4  . MAN J 4 .   ? 161.805 152.769 104.208 1.00 108.43 ? 5   MAN c C4  1 
HETATM 14741 C  C5  . MAN J 4 .   ? 160.706 153.750 103.812 1.00 107.12 ? 5   MAN c C5  1 
HETATM 14742 C  C6  . MAN J 4 .   ? 160.982 154.450 102.503 1.00 104.31 ? 5   MAN c C6  1 
HETATM 14743 O  O2  . MAN J 4 .   ? 160.112 150.318 104.355 1.00 97.87  ? 5   MAN c O2  1 
HETATM 14744 O  O3  . MAN J 4 .   ? 162.384 151.057 105.811 1.00 108.79 ? 5   MAN c O3  1 
HETATM 14745 O  O4  . MAN J 4 .   ? 163.015 153.486 104.421 1.00 103.55 ? 5   MAN c O4  1 
HETATM 14746 O  O5  . MAN J 4 .   ? 159.466 153.044 103.648 1.00 102.21 ? 5   MAN c O5  1 
HETATM 14747 O  O6  . MAN J 4 .   ? 159.928 155.340 102.167 1.00 101.32 ? 5   MAN c O6  1 
HETATM 14748 C  C1  . NAG K 5 .   ? 132.129 160.907 85.853  1.00 68.74  ? 1   NAG H C1  1 
HETATM 14749 C  C2  . NAG K 5 .   ? 131.423 162.221 86.179  1.00 73.80  ? 1   NAG H C2  1 
HETATM 14750 C  C3  . NAG K 5 .   ? 132.404 163.386 86.079  1.00 76.14  ? 1   NAG H C3  1 
HETATM 14751 C  C4  . NAG K 5 .   ? 133.631 163.117 86.937  1.00 77.44  ? 1   NAG H C4  1 
HETATM 14752 C  C5  . NAG K 5 .   ? 134.241 161.773 86.552  1.00 75.74  ? 1   NAG H C5  1 
HETATM 14753 C  C6  . NAG K 5 .   ? 135.430 161.382 87.402  1.00 71.79  ? 1   NAG H C6  1 
HETATM 14754 C  C7  . NAG K 5 .   ? 129.182 163.075 85.656  1.00 81.58  ? 1   NAG H C7  1 
HETATM 14755 C  C8  . NAG K 5 .   ? 128.117 163.201 84.606  1.00 75.77  ? 1   NAG H C8  1 
HETATM 14756 N  N2  . NAG K 5 .   ? 130.293 162.429 85.288  1.00 76.81  ? 1   NAG H N2  1 
HETATM 14757 O  O3  . NAG K 5 .   ? 131.765 164.583 86.512  1.00 83.22  ? 1   NAG H O3  1 
HETATM 14758 O  O4  . NAG K 5 .   ? 134.590 164.149 86.737  1.00 74.76  ? 1   NAG H O4  1 
HETATM 14759 O  O5  . NAG K 5 .   ? 133.256 160.743 86.714  1.00 71.85  ? 1   NAG H O5  1 
HETATM 14760 O  O6  . NAG K 5 .   ? 135.118 161.410 88.787  1.00 71.08  ? 1   NAG H O6  1 
HETATM 14761 O  O7  . NAG K 5 .   ? 129.040 163.536 86.785  1.00 82.64  ? 1   NAG H O7  1 
HETATM 14762 C  C1  . NAG K 5 .   ? 134.824 164.815 87.992  1.00 33.32  ? 2   NAG H C1  1 
HETATM 14763 C  C2  . NAG K 5 .   ? 135.957 165.821 87.790  1.00 33.32  ? 2   NAG H C2  1 
HETATM 14764 C  C3  . NAG K 5 .   ? 136.205 166.604 89.076  1.00 33.32  ? 2   NAG H C3  1 
HETATM 14765 C  C4  . NAG K 5 .   ? 134.907 167.217 89.583  1.00 33.32  ? 2   NAG H C4  1 
HETATM 14766 C  C5  . NAG K 5 .   ? 133.837 166.138 89.712  1.00 33.32  ? 2   NAG H C5  1 
HETATM 14767 C  C6  . NAG K 5 .   ? 132.490 166.685 90.124  1.00 33.32  ? 2   NAG H C6  1 
HETATM 14768 C  C7  . NAG K 5 .   ? 137.470 164.916 86.083  1.00 33.32  ? 2   NAG H C7  1 
HETATM 14769 C  C8  . NAG K 5 .   ? 138.757 164.188 85.826  1.00 33.32  ? 2   NAG H C8  1 
HETATM 14770 N  N2  . NAG K 5 .   ? 137.169 165.140 87.366  1.00 33.32  ? 2   NAG H N2  1 
HETATM 14771 O  O3  . NAG K 5 .   ? 137.153 167.635 88.815  1.00 33.32  ? 2   NAG H O3  1 
HETATM 14772 O  O4  . NAG K 5 .   ? 135.116 167.821 90.855  1.00 33.32  ? 2   NAG H O4  1 
HETATM 14773 O  O5  . NAG K 5 .   ? 133.654 165.495 88.443  1.00 33.32  ? 2   NAG H O5  1 
HETATM 14774 O  O6  . NAG K 5 .   ? 132.551 167.279 91.412  1.00 33.32  ? 2   NAG H O6  1 
HETATM 14775 O  O7  . NAG K 5 .   ? 136.739 165.288 85.169  1.00 33.32  ? 2   NAG H O7  1 
HETATM 14776 C  C1  . NAG L 4 .   ? 136.282 131.277 97.305  1.00 72.71  ? 1   NAG d C1  1 
HETATM 14777 C  C2  . NAG L 4 .   ? 135.266 132.040 96.452  1.00 79.25  ? 1   NAG d C2  1 
HETATM 14778 C  C3  . NAG L 4 .   ? 133.843 131.748 96.921  1.00 80.70  ? 1   NAG d C3  1 
HETATM 14779 C  C4  . NAG L 4 .   ? 133.610 130.249 96.861  1.00 85.22  ? 1   NAG d C4  1 
HETATM 14780 C  C5  . NAG L 4 .   ? 134.613 129.580 97.793  1.00 84.05  ? 1   NAG d C5  1 
HETATM 14781 C  C6  . NAG L 4 .   ? 134.501 128.074 97.815  1.00 88.15  ? 1   NAG d C6  1 
HETATM 14782 C  C7  . NAG L 4 .   ? 136.078 134.127 95.448  1.00 74.02  ? 1   NAG d C7  1 
HETATM 14783 C  C8  . NAG L 4 .   ? 136.282 135.601 95.643  1.00 64.66  ? 1   NAG d C8  1 
HETATM 14784 N  N2  . NAG L 4 .   ? 135.534 133.469 96.478  1.00 75.05  ? 1   NAG d N2  1 
HETATM 14785 O  O3  . NAG L 4 .   ? 132.902 132.426 96.096  1.00 74.73  ? 1   NAG d O3  1 
HETATM 14786 O  O4  . NAG L 4 .   ? 132.262 129.906 97.177  1.00 85.84  ? 1   NAG d O4  1 
HETATM 14787 O  O5  . NAG L 4 .   ? 135.941 129.885 97.337  1.00 82.47  ? 1   NAG d O5  1 
HETATM 14788 O  O6  . NAG L 4 .   ? 135.546 127.493 98.579  1.00 89.02  ? 1   NAG d O6  1 
HETATM 14789 O  O7  . NAG L 4 .   ? 136.391 133.559 94.404  1.00 71.28  ? 1   NAG d O7  1 
HETATM 14790 C  C1  . NAG L 4 .   ? 131.704 129.264 95.995  1.00 17.86  ? 2   NAG d C1  1 
HETATM 14791 C  C2  . NAG L 4 .   ? 130.286 128.765 96.273  1.00 17.86  ? 2   NAG d C2  1 
HETATM 14792 C  C3  . NAG L 4 .   ? 129.697 128.135 95.014  1.00 17.86  ? 2   NAG d C3  1 
HETATM 14793 C  C4  . NAG L 4 .   ? 129.781 129.104 93.842  1.00 17.86  ? 2   NAG d C4  1 
HETATM 14794 C  C5  . NAG L 4 .   ? 131.222 129.581 93.675  1.00 17.86  ? 2   NAG d C5  1 
HETATM 14795 C  C6  . NAG L 4 .   ? 131.390 130.616 92.586  1.00 17.86  ? 2   NAG d C6  1 
HETATM 14796 C  C7  . NAG L 4 .   ? 130.220 128.157 98.652  1.00 17.86  ? 2   NAG d C7  1 
HETATM 14797 C  C8  . NAG L 4 .   ? 130.206 127.029 99.639  1.00 17.86  ? 2   NAG d C8  1 
HETATM 14798 N  N2  . NAG L 4 .   ? 130.278 127.805 97.365  1.00 17.86  ? 2   NAG d N2  1 
HETATM 14799 O  O3  . NAG L 4 .   ? 128.346 127.758 95.256  1.00 17.86  ? 2   NAG d O3  1 
HETATM 14800 O  O4  . NAG L 4 .   ? 129.388 128.434 92.648  1.00 17.86  ? 2   NAG d O4  1 
HETATM 14801 O  O5  . NAG L 4 .   ? 131.679 130.181 94.897  1.00 17.86  ? 2   NAG d O5  1 
HETATM 14802 O  O6  . NAG L 4 .   ? 130.613 131.775 92.845  1.00 17.86  ? 2   NAG d O6  1 
HETATM 14803 O  O7  . NAG L 4 .   ? 130.191 129.333 99.005  1.00 17.86  ? 2   NAG d O7  1 
HETATM 14804 C  C1  . BMA L 4 .   ? 128.172 128.955 92.073  1.00 111.81 ? 3   BMA d C1  1 
HETATM 14805 C  C2  . BMA L 4 .   ? 127.973 128.213 90.756  1.00 114.13 ? 3   BMA d C2  1 
HETATM 14806 C  C3  . BMA L 4 .   ? 126.679 128.648 90.085  1.00 111.13 ? 3   BMA d C3  1 
HETATM 14807 C  C4  . BMA L 4 .   ? 125.513 128.484 91.045  1.00 113.15 ? 3   BMA d C4  1 
HETATM 14808 C  C5  . BMA L 4 .   ? 125.802 129.235 92.340  1.00 113.07 ? 3   BMA d C5  1 
HETATM 14809 C  C6  . BMA L 4 .   ? 124.728 129.031 93.381  1.00 103.47 ? 3   BMA d C6  1 
HETATM 14810 O  O2  . BMA L 4 .   ? 127.938 126.812 91.003  1.00 114.81 ? 3   BMA d O2  1 
HETATM 14811 O  O3  . BMA L 4 .   ? 126.450 127.851 88.930  1.00 104.24 ? 3   BMA d O3  1 
HETATM 14812 O  O4  . BMA L 4 .   ? 124.317 128.988 90.460  1.00 110.61 ? 3   BMA d O4  1 
HETATM 14813 O  O5  . BMA L 4 .   ? 127.033 128.762 92.913  1.00 116.53 ? 3   BMA d O5  1 
HETATM 14814 O  O6  . BMA L 4 .   ? 125.148 129.529 94.640  1.00 105.58 ? 3   BMA d O6  1 
HETATM 14815 C  C1  . MAN L 4 .   ? 126.794 128.595 87.756  1.00 22.94  ? 4   MAN d C1  1 
HETATM 14816 C  C2  . MAN L 4 .   ? 125.770 128.258 86.685  1.00 22.94  ? 4   MAN d C2  1 
HETATM 14817 C  C3  . MAN L 4 .   ? 125.843 126.775 86.351  1.00 22.94  ? 4   MAN d C3  1 
HETATM 14818 C  C4  . MAN L 4 .   ? 127.267 126.382 85.983  1.00 22.94  ? 4   MAN d C4  1 
HETATM 14819 C  C5  . MAN L 4 .   ? 128.237 126.830 87.072  1.00 22.94  ? 4   MAN d C5  1 
HETATM 14820 C  C6  . MAN L 4 .   ? 129.680 126.591 86.703  1.00 22.94  ? 4   MAN d C6  1 
HETATM 14821 O  O2  . MAN L 4 .   ? 126.020 129.038 85.521  1.00 22.94  ? 4   MAN d O2  1 
HETATM 14822 O  O3  . MAN L 4 .   ? 124.954 126.472 85.282  1.00 22.94  ? 4   MAN d O3  1 
HETATM 14823 O  O4  . MAN L 4 .   ? 127.368 124.969 85.843  1.00 22.94  ? 4   MAN d O4  1 
HETATM 14824 O  O5  . MAN L 4 .   ? 128.095 128.241 87.299  1.00 22.94  ? 4   MAN d O5  1 
HETATM 14825 O  O6  . MAN L 4 .   ? 129.900 125.227 86.376  1.00 22.94  ? 4   MAN d O6  1 
HETATM 14826 C  C1  . MAN L 4 .   ? 124.072 129.418 95.585  1.00 100.29 ? 5   MAN d C1  1 
HETATM 14827 C  C2  . MAN L 4 .   ? 124.489 130.193 96.831  1.00 102.67 ? 5   MAN d C2  1 
HETATM 14828 C  C3  . MAN L 4 .   ? 125.675 129.515 97.500  1.00 104.27 ? 5   MAN d C3  1 
HETATM 14829 C  C4  . MAN L 4 .   ? 125.349 128.056 97.788  1.00 101.88 ? 5   MAN d C4  1 
HETATM 14830 C  C5  . MAN L 4 .   ? 124.922 127.361 96.498  1.00 101.96 ? 5   MAN d C5  1 
HETATM 14831 C  C6  . MAN L 4 .   ? 124.483 125.931 96.713  1.00 101.37 ? 5   MAN d C6  1 
HETATM 14832 O  O2  . MAN L 4 .   ? 123.396 130.269 97.738  1.00 99.16  ? 5   MAN d O2  1 
HETATM 14833 O  O3  . MAN L 4 .   ? 126.017 130.199 98.701  1.00 97.72  ? 5   MAN d O3  1 
HETATM 14834 O  O4  . MAN L 4 .   ? 126.484 127.388 98.328  1.00 99.56  ? 5   MAN d O4  1 
HETATM 14835 O  O5  . MAN L 4 .   ? 123.802 128.055 95.926  1.00 104.42 ? 5   MAN d O5  1 
HETATM 14836 O  O6  . MAN L 4 .   ? 124.195 125.276 95.485  1.00 91.59  ? 5   MAN d O6  1 
HETATM 14837 C  C1  . NAG M 4 .   ? 113.845 154.120 115.490 1.00 45.06  ? 1   NAG e C1  1 
HETATM 14838 C  C2  . NAG M 4 .   ? 112.417 154.615 115.282 1.00 43.44  ? 1   NAG e C2  1 
HETATM 14839 C  C3  . NAG M 4 .   ? 112.280 155.268 113.909 1.00 46.41  ? 1   NAG e C3  1 
HETATM 14840 C  C4  . NAG M 4 .   ? 113.364 156.312 113.674 1.00 42.85  ? 1   NAG e C4  1 
HETATM 14841 C  C5  . NAG M 4 .   ? 114.742 155.748 114.000 1.00 42.29  ? 1   NAG e C5  1 
HETATM 14842 C  C6  . NAG M 4 .   ? 115.826 156.798 113.968 1.00 49.34  ? 1   NAG e C6  1 
HETATM 14843 C  C7  . NAG M 4 .   ? 110.301 153.645 116.046 1.00 49.36  ? 1   NAG e C7  1 
HETATM 14844 C  C8  . NAG M 4 .   ? 109.432 152.423 116.071 1.00 44.46  ? 1   NAG e C8  1 
HETATM 14845 N  N2  . NAG M 4 .   ? 111.471 153.520 115.416 1.00 45.00  ? 1   NAG e N2  1 
HETATM 14846 O  O3  . NAG M 4 .   ? 111.002 155.884 113.815 1.00 46.91  ? 1   NAG e O3  1 
HETATM 14847 O  O4  . NAG M 4 .   ? 113.384 156.640 112.290 1.00 49.09  ? 1   NAG e O4  1 
HETATM 14848 O  O5  . NAG M 4 .   ? 114.751 155.203 115.325 1.00 50.55  ? 1   NAG e O5  1 
HETATM 14849 O  O6  . NAG M 4 .   ? 117.113 156.215 114.085 1.00 59.06  ? 1   NAG e O6  1 
HETATM 14850 O  O7  . NAG M 4 .   ? 109.959 154.697 116.575 1.00 56.90  ? 1   NAG e O7  1 
HETATM 14851 C  C1  . NAG M 4 .   ? 112.836 157.932 111.996 1.00 47.29  ? 2   NAG e C1  1 
HETATM 14852 C  C2  . NAG M 4 .   ? 113.488 158.414 110.703 1.00 46.51  ? 2   NAG e C2  1 
HETATM 14853 C  C3  . NAG M 4 .   ? 112.913 159.764 110.294 1.00 48.73  ? 2   NAG e C3  1 
HETATM 14854 C  C4  . NAG M 4 .   ? 111.398 159.685 110.210 1.00 50.57  ? 2   NAG e C4  1 
HETATM 14855 C  C5  . NAG M 4 .   ? 110.833 159.150 111.522 1.00 50.46  ? 2   NAG e C5  1 
HETATM 14856 C  C6  . NAG M 4 .   ? 109.341 158.930 111.478 1.00 54.53  ? 2   NAG e C6  1 
HETATM 14857 C  C7  . NAG M 4 .   ? 115.774 157.656 110.248 1.00 44.95  ? 2   NAG e C7  1 
HETATM 14858 C  C8  . NAG M 4 .   ? 117.232 157.889 110.507 1.00 37.66  ? 2   NAG e C8  1 
HETATM 14859 N  N2  . NAG M 4 .   ? 114.931 158.498 110.851 1.00 44.48  ? 2   NAG e N2  1 
HETATM 14860 O  O3  . NAG M 4 .   ? 113.446 160.128 109.026 1.00 52.41  ? 2   NAG e O3  1 
HETATM 14861 O  O4  . NAG M 4 .   ? 110.880 160.991 109.985 1.00 61.84  ? 2   NAG e O4  1 
HETATM 14862 O  O5  . NAG M 4 .   ? 111.422 157.877 111.825 1.00 50.81  ? 2   NAG e O5  1 
HETATM 14863 O  O6  . NAG M 4 .   ? 108.848 158.547 112.751 1.00 56.68  ? 2   NAG e O6  1 
HETATM 14864 O  O7  . NAG M 4 .   ? 115.380 156.749 109.524 1.00 50.17  ? 2   NAG e O7  1 
HETATM 14865 C  C1  . BMA M 4 .   ? 110.232 161.102 108.702 1.00 66.65  ? 3   BMA e C1  1 
HETATM 14866 C  C2  . BMA M 4 .   ? 109.458 162.413 108.721 1.00 72.61  ? 3   BMA e C2  1 
HETATM 14867 C  C3  . BMA M 4 .   ? 108.733 162.617 107.400 1.00 75.80  ? 3   BMA e C3  1 
HETATM 14868 C  C4  . BMA M 4 .   ? 109.701 162.498 106.233 1.00 75.90  ? 3   BMA e C4  1 
HETATM 14869 C  C5  . BMA M 4 .   ? 110.512 161.209 106.327 1.00 72.09  ? 3   BMA e C5  1 
HETATM 14870 C  C6  . BMA M 4 .   ? 111.609 161.153 105.291 1.00 70.64  ? 3   BMA e C6  1 
HETATM 14871 O  O2  . BMA M 4 .   ? 110.356 163.491 108.955 1.00 65.51  ? 3   BMA e O2  1 
HETATM 14872 O  O3  . BMA M 4 .   ? 108.131 163.906 107.379 1.00 73.09  ? 3   BMA e O3  1 
HETATM 14873 O  O4  . BMA M 4 .   ? 108.977 162.490 105.008 1.00 76.65  ? 3   BMA e O4  1 
HETATM 14874 O  O5  . BMA M 4 .   ? 111.152 161.120 107.611 1.00 70.89  ? 3   BMA e O5  1 
HETATM 14875 O  O6  . BMA M 4 .   ? 112.391 162.338 105.328 1.00 83.62  ? 3   BMA e O6  1 
HETATM 14876 C  C1  . MAN M 4 .   ? 106.718 163.780 107.613 1.00 34.22  ? 4   MAN e C1  1 
HETATM 14877 C  C2  . MAN M 4 .   ? 106.005 164.918 106.889 1.00 34.22  ? 4   MAN e C2  1 
HETATM 14878 C  C3  . MAN M 4 .   ? 106.391 166.260 107.499 1.00 34.22  ? 4   MAN e C3  1 
HETATM 14879 C  C4  . MAN M 4 .   ? 106.175 166.249 109.005 1.00 34.22  ? 4   MAN e C4  1 
HETATM 14880 C  C5  . MAN M 4 .   ? 106.891 165.054 109.626 1.00 34.22  ? 4   MAN e C5  1 
HETATM 14881 C  C6  . MAN M 4 .   ? 106.632 164.912 111.108 1.00 34.22  ? 4   MAN e C6  1 
HETATM 14882 O  O2  . MAN M 4 .   ? 104.595 164.729 106.956 1.00 34.22  ? 4   MAN e O2  1 
HETATM 14883 O  O3  . MAN M 4 .   ? 105.625 167.303 106.907 1.00 34.22  ? 4   MAN e O3  1 
HETATM 14884 O  O4  . MAN M 4 .   ? 106.688 167.447 109.578 1.00 34.22  ? 4   MAN e O4  1 
HETATM 14885 O  O5  . MAN M 4 .   ? 106.429 163.843 109.009 1.00 34.22  ? 4   MAN e O5  1 
HETATM 14886 O  O6  . MAN M 4 .   ? 107.304 163.780 111.642 1.00 34.22  ? 4   MAN e O6  1 
HETATM 14887 C  C1  . MAN M 4 .   ? 113.333 162.338 104.237 1.00 87.63  ? 5   MAN e C1  1 
HETATM 14888 C  C2  . MAN M 4 .   ? 114.671 162.835 104.778 1.00 90.59  ? 5   MAN e C2  1 
HETATM 14889 C  C3  . MAN M 4 .   ? 114.559 164.291 105.206 1.00 92.39  ? 5   MAN e C3  1 
HETATM 14890 C  C4  . MAN M 4 .   ? 114.032 165.136 104.057 1.00 88.11  ? 5   MAN e C4  1 
HETATM 14891 C  C5  . MAN M 4 .   ? 112.713 164.556 103.558 1.00 91.80  ? 5   MAN e C5  1 
HETATM 14892 C  C6  . MAN M 4 .   ? 112.169 165.281 102.349 1.00 88.81  ? 5   MAN e C6  1 
HETATM 14893 O  O2  . MAN M 4 .   ? 115.673 162.692 103.776 1.00 84.06  ? 5   MAN e O2  1 
HETATM 14894 O  O3  . MAN M 4 .   ? 115.823 164.781 105.638 1.00 86.75  ? 5   MAN e O3  1 
HETATM 14895 O  O4  . MAN M 4 .   ? 113.818 166.475 104.492 1.00 75.77  ? 5   MAN e O4  1 
HETATM 14896 O  O5  . MAN M 4 .   ? 112.903 163.186 103.168 1.00 91.13  ? 5   MAN e O5  1 
HETATM 14897 O  O6  . MAN M 4 .   ? 110.884 164.797 101.991 1.00 80.34  ? 5   MAN e O6  1 
HETATM 14898 C  C1  . NAG N 5 .   ? 98.645  138.253 85.570  1.00 75.59  ? 1   NAG I C1  1 
HETATM 14899 C  C2  . NAG N 5 .   ? 97.296  137.694 86.017  1.00 78.83  ? 1   NAG I C2  1 
HETATM 14900 C  C3  . NAG N 5 .   ? 96.299  138.832 86.210  1.00 76.98  ? 1   NAG I C3  1 
HETATM 14901 C  C4  . NAG N 5 .   ? 96.867  139.889 87.150  1.00 77.45  ? 1   NAG I C4  1 
HETATM 14902 C  C5  . NAG N 5 .   ? 98.263  140.322 86.705  1.00 83.01  ? 1   NAG I C5  1 
HETATM 14903 C  C6  . NAG N 5 .   ? 98.946  141.228 87.705  1.00 79.62  ? 1   NAG I C6  1 
HETATM 14904 C  C7  . NAG N 5 .   ? 96.126  135.615 85.453  1.00 80.71  ? 1   NAG I C7  1 
HETATM 14905 C  C8  . NAG N 5 .   ? 95.668  134.707 84.349  1.00 77.10  ? 1   NAG I C8  1 
HETATM 14906 N  N2  . NAG N 5 .   ? 96.785  136.716 85.071  1.00 81.77  ? 1   NAG I N2  1 
HETATM 14907 O  O3  . NAG N 5 .   ? 95.091  138.310 86.752  1.00 76.63  ? 1   NAG I O3  1 
HETATM 14908 O  O4  . NAG N 5 .   ? 96.012  141.029 87.118  1.00 71.16  ? 1   NAG I O4  1 
HETATM 14909 O  O5  . NAG N 5 .   ? 99.120  139.179 86.544  1.00 80.22  ? 1   NAG I O5  1 
HETATM 14910 O  O6  . NAG N 5 .   ? 98.924  140.663 89.009  1.00 75.04  ? 1   NAG I O6  1 
HETATM 14911 O  O7  . NAG N 5 .   ? 95.904  135.366 86.634  1.00 76.08  ? 1   NAG I O7  1 
HETATM 14912 C  C1  . NAG N 5 .   ? 95.598  141.433 88.443  1.00 18.58  ? 2   NAG I C1  1 
HETATM 14913 C  C2  . NAG N 5 .   ? 94.866  142.770 88.326  1.00 18.58  ? 2   NAG I C2  1 
HETATM 14914 C  C3  . NAG N 5 .   ? 94.383  143.224 89.699  1.00 18.58  ? 2   NAG I C3  1 
HETATM 14915 C  C4  . NAG N 5 .   ? 93.526  142.133 90.325  1.00 18.58  ? 2   NAG I C4  1 
HETATM 14916 C  C5  . NAG N 5 .   ? 94.314  140.827 90.375  1.00 18.58  ? 2   NAG I C5  1 
HETATM 14917 C  C6  . NAG N 5 .   ? 93.503  139.668 90.908  1.00 18.58  ? 2   NAG I C6  1 
HETATM 14918 C  C7  . NAG N 5 .   ? 95.781  143.996 86.405  1.00 18.58  ? 2   NAG I C7  1 
HETATM 14919 C  C8  . NAG N 5 .   ? 96.714  145.082 85.958  1.00 18.58  ? 2   NAG I C8  1 
HETATM 14920 N  N2  . NAG N 5 .   ? 95.720  143.782 87.724  1.00 18.58  ? 2   NAG I N2  1 
HETATM 14921 O  O3  . NAG N 5 .   ? 93.639  144.430 89.573  1.00 18.58  ? 2   NAG I O3  1 
HETATM 14922 O  O4  . NAG N 5 .   ? 93.144  142.503 91.646  1.00 18.58  ? 2   NAG I O4  1 
HETATM 14923 O  O5  . NAG N 5 .   ? 94.736  140.466 89.049  1.00 18.58  ? 2   NAG I O5  1 
HETATM 14924 O  O6  . NAG N 5 .   ? 93.076  139.908 92.241  1.00 18.58  ? 2   NAG I O6  1 
HETATM 14925 O  O7  . NAG N 5 .   ? 95.117  143.340 85.608  1.00 18.58  ? 2   NAG I O7  1 
HETATM 14926 CL CL  . CL  O 6 .   ? 115.313 115.313 122.834 1.00 52.55  ? 501 CL  D CL  1 
HETATM 14927 N  N   . ABU P 7 .   ? 119.096 103.814 100.157 1.00 35.56  ? 501 ABU E N   1 
HETATM 14928 C  CD  . ABU P 7 .   ? 118.439 105.015 99.589  1.00 35.05  ? 501 ABU E CD  1 
HETATM 14929 C  CB  . ABU P 7 .   ? 116.958 104.817 99.451  1.00 34.46  ? 501 ABU E CB  1 
HETATM 14930 C  CG  . ABU P 7 .   ? 116.253 106.129 99.155  1.00 33.53  ? 501 ABU E CG  1 
HETATM 14931 C  C   . ABU P 7 .   ? 114.743 106.017 99.128  1.00 48.11  ? 501 ABU E C   1 
HETATM 14932 O  O   . ABU P 7 .   ? 114.086 107.075 99.222  1.00 51.53  ? 501 ABU E O   1 
HETATM 14933 O  OXT . ABU P 7 .   ? 114.239 104.885 99.014  1.00 53.06  ? 501 ABU E OXT 1 
HETATM 14934 N  N   . ABU Q 7 .   ? 152.826 138.499 98.720  1.00 34.03  ? 501 ABU B N   1 
HETATM 14935 C  CD  . ABU Q 7 .   ? 152.703 137.080 98.308  1.00 35.15  ? 501 ABU B CD  1 
HETATM 14936 C  CB  . ABU Q 7 .   ? 154.038 136.388 98.278  1.00 34.60  ? 501 ABU B CB  1 
HETATM 14937 C  CG  . ABU Q 7 .   ? 153.885 134.911 97.954  1.00 39.80  ? 501 ABU B CG  1 
HETATM 14938 C  C   . ABU Q 7 .   ? 155.178 134.119 97.956  1.00 49.70  ? 501 ABU B C   1 
HETATM 14939 O  O   . ABU Q 7 .   ? 155.794 133.992 99.031  1.00 49.55  ? 501 ABU B O   1 
HETATM 14940 O  OXT . ABU Q 7 .   ? 155.553 133.630 96.868  1.00 54.31  ? 501 ABU B OXT 1 
HETATM 14941 CL CL  . CL  R 6 .   ? 149.824 128.697 122.751 1.00 65.33  ? 501 CL  A CL  1 
# 
