data_9FF1
# 
_entry.id   9FF1 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FF1         pdb_00009ff1 10.2210/pdb9ff1/pdb 
WWPDB D_1292138613 ?            ?                   
EMDB  EMD-50348    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-06-04 ? 
2 'EM metadata'     1 0 2025-06-04 ? 
3 'Additional map'  1 0 2025-06-04 1 
4 FSC               1 0 2025-06-04 ? 
5 'Half map'        1 0 2025-06-04 1 
6 'Half map'        1 0 2025-06-04 2 
7 Image             1 0 2025-06-04 ? 
8 Mask              1 0 2025-06-04 1 
9 'Primary map'     1 0 2025-06-04 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 FSC               repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 'Half map'        repository 'Initial release' ? ? 
7 7 Image             repository 'Initial release' ? ? 
8 8 Mask              repository 'Initial release' ? ? 
9 9 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FF1 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric desensitised state' 
_pdbx_database_related.db_id          EMD-50348 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              radu@mrc-lmb.cam.ac.uk 
_pdbx_contact_author.name_first         'A. Radu' 
_pdbx_contact_author.name_last          Aricescu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3783-1388 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Mihaylov, D.B.'  1 0000-0002-8375-3360 
'Malinauskas, T.' 2 0000-0002-4847-5529 
'Aricescu, A.R.'  3 0000-0003-3783-1388 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric desensitised state' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Mihaylov, D.B.'  1 0000-0002-8375-3360 
primary 'Malinauskas, T.' 2 0000-0002-4847-5529 
primary 'Aricescu, A.R.'  3 0000-0003-3783-1388 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Gamma-aminobutyric acid receptor subunit beta-3' 45643.246 5 ? ? ? ? 
2 branched    man 
;alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
;
910.823   5 ? ? ? ? 
3 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   5 ? ? ? ? 
4 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   5 ? ? ? ? 
5 non-polymer syn HISTAMINE 111.145   4 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'GABA(A) receptor subunit beta-3' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MDEKTTGWRGGHVVEGLAGELEQLRARLEHHPQGQREPDYDIPTTENLYFQGTGQSVNDPGNMSFVKETVDKLLKGYDIR
LRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV
HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQF
SIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINT
HLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFSQPARAAAIDRWSRIVFPFTFSLFNLVYWLYYVN
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MDEKTTGWRGGHVVEGLAGELEQLRARLEHHPQGQREPDYDIPTTENLYFQGTGQSVNDPGNMSFVKETVDKLLKGYDIR
LRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV
HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQF
SIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINT
HLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFSQPARAAAIDRWSRIVFPFTFSLFNLVYWLYYVN
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 2-acetamido-2-deoxy-beta-D-glucopyranose NAG 
5 HISTAMINE                                HSM 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   GLU n 
1 4   LYS n 
1 5   THR n 
1 6   THR n 
1 7   GLY n 
1 8   TRP n 
1 9   ARG n 
1 10  GLY n 
1 11  GLY n 
1 12  HIS n 
1 13  VAL n 
1 14  VAL n 
1 15  GLU n 
1 16  GLY n 
1 17  LEU n 
1 18  ALA n 
1 19  GLY n 
1 20  GLU n 
1 21  LEU n 
1 22  GLU n 
1 23  GLN n 
1 24  LEU n 
1 25  ARG n 
1 26  ALA n 
1 27  ARG n 
1 28  LEU n 
1 29  GLU n 
1 30  HIS n 
1 31  HIS n 
1 32  PRO n 
1 33  GLN n 
1 34  GLY n 
1 35  GLN n 
1 36  ARG n 
1 37  GLU n 
1 38  PRO n 
1 39  ASP n 
1 40  TYR n 
1 41  ASP n 
1 42  ILE n 
1 43  PRO n 
1 44  THR n 
1 45  THR n 
1 46  GLU n 
1 47  ASN n 
1 48  LEU n 
1 49  TYR n 
1 50  PHE n 
1 51  GLN n 
1 52  GLY n 
1 53  THR n 
1 54  GLY n 
1 55  GLN n 
1 56  SER n 
1 57  VAL n 
1 58  ASN n 
1 59  ASP n 
1 60  PRO n 
1 61  GLY n 
1 62  ASN n 
1 63  MET n 
1 64  SER n 
1 65  PHE n 
1 66  VAL n 
1 67  LYS n 
1 68  GLU n 
1 69  THR n 
1 70  VAL n 
1 71  ASP n 
1 72  LYS n 
1 73  LEU n 
1 74  LEU n 
1 75  LYS n 
1 76  GLY n 
1 77  TYR n 
1 78  ASP n 
1 79  ILE n 
1 80  ARG n 
1 81  LEU n 
1 82  ARG n 
1 83  PRO n 
1 84  ASP n 
1 85  PHE n 
1 86  GLY n 
1 87  GLY n 
1 88  PRO n 
1 89  PRO n 
1 90  VAL n 
1 91  CYS n 
1 92  VAL n 
1 93  GLY n 
1 94  MET n 
1 95  ASN n 
1 96  ILE n 
1 97  ASP n 
1 98  ILE n 
1 99  ALA n 
1 100 SER n 
1 101 ILE n 
1 102 ASP n 
1 103 MET n 
1 104 VAL n 
1 105 SER n 
1 106 GLU n 
1 107 VAL n 
1 108 ASN n 
1 109 MET n 
1 110 ASP n 
1 111 TYR n 
1 112 THR n 
1 113 LEU n 
1 114 THR n 
1 115 MET n 
1 116 TYR n 
1 117 PHE n 
1 118 GLN n 
1 119 GLN n 
1 120 TYR n 
1 121 TRP n 
1 122 ARG n 
1 123 ASP n 
1 124 LYS n 
1 125 ARG n 
1 126 LEU n 
1 127 ALA n 
1 128 TYR n 
1 129 SER n 
1 130 GLY n 
1 131 ILE n 
1 132 PRO n 
1 133 LEU n 
1 134 ASN n 
1 135 LEU n 
1 136 THR n 
1 137 LEU n 
1 138 ASP n 
1 139 ASN n 
1 140 ARG n 
1 141 VAL n 
1 142 ALA n 
1 143 ASP n 
1 144 GLN n 
1 145 LEU n 
1 146 TRP n 
1 147 VAL n 
1 148 PRO n 
1 149 ASP n 
1 150 THR n 
1 151 TYR n 
1 152 PHE n 
1 153 LEU n 
1 154 ASN n 
1 155 ASP n 
1 156 LYS n 
1 157 LYS n 
1 158 SER n 
1 159 PHE n 
1 160 VAL n 
1 161 HIS n 
1 162 GLY n 
1 163 VAL n 
1 164 THR n 
1 165 VAL n 
1 166 LYS n 
1 167 ASN n 
1 168 ARG n 
1 169 MET n 
1 170 ILE n 
1 171 ARG n 
1 172 LEU n 
1 173 HIS n 
1 174 PRO n 
1 175 ASP n 
1 176 GLY n 
1 177 THR n 
1 178 VAL n 
1 179 LEU n 
1 180 TYR n 
1 181 GLY n 
1 182 LEU n 
1 183 ARG n 
1 184 ILE n 
1 185 THR n 
1 186 THR n 
1 187 THR n 
1 188 ALA n 
1 189 ALA n 
1 190 CYS n 
1 191 MET n 
1 192 MET n 
1 193 ASP n 
1 194 LEU n 
1 195 ARG n 
1 196 ARG n 
1 197 TYR n 
1 198 PRO n 
1 199 LEU n 
1 200 ASP n 
1 201 GLU n 
1 202 GLN n 
1 203 ASN n 
1 204 CYS n 
1 205 THR n 
1 206 LEU n 
1 207 GLU n 
1 208 ILE n 
1 209 GLU n 
1 210 SER n 
1 211 TYR n 
1 212 GLY n 
1 213 TYR n 
1 214 THR n 
1 215 THR n 
1 216 ASP n 
1 217 ASP n 
1 218 ILE n 
1 219 GLU n 
1 220 PHE n 
1 221 TYR n 
1 222 TRP n 
1 223 ARG n 
1 224 GLY n 
1 225 GLY n 
1 226 ASP n 
1 227 LYS n 
1 228 ALA n 
1 229 VAL n 
1 230 THR n 
1 231 GLY n 
1 232 VAL n 
1 233 GLU n 
1 234 ARG n 
1 235 ILE n 
1 236 GLU n 
1 237 LEU n 
1 238 PRO n 
1 239 GLN n 
1 240 PHE n 
1 241 SER n 
1 242 ILE n 
1 243 VAL n 
1 244 GLU n 
1 245 HIS n 
1 246 ARG n 
1 247 LEU n 
1 248 VAL n 
1 249 SER n 
1 250 ARG n 
1 251 ASN n 
1 252 VAL n 
1 253 VAL n 
1 254 PHE n 
1 255 ALA n 
1 256 THR n 
1 257 GLY n 
1 258 ALA n 
1 259 TYR n 
1 260 PRO n 
1 261 ARG n 
1 262 LEU n 
1 263 SER n 
1 264 LEU n 
1 265 SER n 
1 266 PHE n 
1 267 ARG n 
1 268 LEU n 
1 269 LYS n 
1 270 ARG n 
1 271 ASN n 
1 272 ILE n 
1 273 GLY n 
1 274 TYR n 
1 275 PHE n 
1 276 ILE n 
1 277 LEU n 
1 278 GLN n 
1 279 THR n 
1 280 TYR n 
1 281 MET n 
1 282 PRO n 
1 283 SER n 
1 284 ILE n 
1 285 LEU n 
1 286 ILE n 
1 287 THR n 
1 288 ILE n 
1 289 LEU n 
1 290 SER n 
1 291 TRP n 
1 292 VAL n 
1 293 SER n 
1 294 PHE n 
1 295 TRP n 
1 296 ILE n 
1 297 ASN n 
1 298 TYR n 
1 299 ASP n 
1 300 ALA n 
1 301 SER n 
1 302 ALA n 
1 303 ALA n 
1 304 ARG n 
1 305 VAL n 
1 306 ALA n 
1 307 LEU n 
1 308 GLY n 
1 309 ILE n 
1 310 THR n 
1 311 THR n 
1 312 VAL n 
1 313 LEU n 
1 314 THR n 
1 315 MET n 
1 316 THR n 
1 317 THR n 
1 318 ILE n 
1 319 ASN n 
1 320 THR n 
1 321 HIS n 
1 322 LEU n 
1 323 ARG n 
1 324 GLU n 
1 325 THR n 
1 326 LEU n 
1 327 PRO n 
1 328 LYS n 
1 329 ILE n 
1 330 PRO n 
1 331 TYR n 
1 332 VAL n 
1 333 LYS n 
1 334 ALA n 
1 335 ILE n 
1 336 ASP n 
1 337 MET n 
1 338 TYR n 
1 339 LEU n 
1 340 MET n 
1 341 GLY n 
1 342 CYS n 
1 343 PHE n 
1 344 VAL n 
1 345 PHE n 
1 346 VAL n 
1 347 PHE n 
1 348 LEU n 
1 349 ALA n 
1 350 LEU n 
1 351 LEU n 
1 352 GLU n 
1 353 TYR n 
1 354 ALA n 
1 355 PHE n 
1 356 VAL n 
1 357 ASN n 
1 358 TYR n 
1 359 ILE n 
1 360 PHE n 
1 361 PHE n 
1 362 SER n 
1 363 GLN n 
1 364 PRO n 
1 365 ALA n 
1 366 ARG n 
1 367 ALA n 
1 368 ALA n 
1 369 ALA n 
1 370 ILE n 
1 371 ASP n 
1 372 ARG n 
1 373 TRP n 
1 374 SER n 
1 375 ARG n 
1 376 ILE n 
1 377 VAL n 
1 378 PHE n 
1 379 PRO n 
1 380 PHE n 
1 381 THR n 
1 382 PHE n 
1 383 SER n 
1 384 LEU n 
1 385 PHE n 
1 386 ASN n 
1 387 LEU n 
1 388 VAL n 
1 389 TYR n 
1 390 TRP n 
1 391 LEU n 
1 392 TYR n 
1 393 TYR n 
1 394 VAL n 
1 395 ASN n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   361 human ? GABRB3 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? 
? ? ? ? ? 'EXPI 293F' ? ? ? ? ? plasmid ? ? ? pHLsec ? ? 
1 2 sample 'Biological sequence' 362 395 human ? GABRB3 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? 
? ? ? ? ? 'EXPI 293F' ? ? ? ? ? plasmid ? ? ? pHLsec ? ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
2 oligosaccharide 
3 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 'DManpa1-3[DManpa1-6]DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-'                                                      
'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/3,5,4/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3/a4-b1_b4-c1_c3-d1_c6-e1' WURCS PDB2Glycan 
1.1.0 
3 2 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{}}}}}' LINUCS PDB-CARE   
?     
4 3 DGlcpNAcb1-4DGlcpNAcb1-                                                                                     
'Glycam Condensed Sequence' GMML       1.0   
5 3 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1'                                                       WURCS PDB2Glycan 
1.1.0 
6 3 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}}'                                                          LINUCS PDB-CARE   
?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 2 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
3 2 4 MAN C1 O1 3 BMA O3 HO3 sing ? 
4 2 5 MAN C1 O1 3 BMA O6 HO6 sing ? 
5 3 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
HSM non-polymer                   . HISTAMINE                                ? 'C5 H9 N3'       111.145 
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose                    'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6' 
180.156 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                         
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose              
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                       
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -53 ?   ?   ?   A . n 
A 1 2   ASP 2   -52 ?   ?   ?   A . n 
A 1 3   GLU 3   -51 ?   ?   ?   A . n 
A 1 4   LYS 4   -50 ?   ?   ?   A . n 
A 1 5   THR 5   -49 ?   ?   ?   A . n 
A 1 6   THR 6   -48 ?   ?   ?   A . n 
A 1 7   GLY 7   -47 ?   ?   ?   A . n 
A 1 8   TRP 8   -46 ?   ?   ?   A . n 
A 1 9   ARG 9   -45 ?   ?   ?   A . n 
A 1 10  GLY 10  -44 ?   ?   ?   A . n 
A 1 11  GLY 11  -43 ?   ?   ?   A . n 
A 1 12  HIS 12  -42 ?   ?   ?   A . n 
A 1 13  VAL 13  -41 ?   ?   ?   A . n 
A 1 14  VAL 14  -40 ?   ?   ?   A . n 
A 1 15  GLU 15  -39 ?   ?   ?   A . n 
A 1 16  GLY 16  -38 ?   ?   ?   A . n 
A 1 17  LEU 17  -37 ?   ?   ?   A . n 
A 1 18  ALA 18  -36 ?   ?   ?   A . n 
A 1 19  GLY 19  -35 ?   ?   ?   A . n 
A 1 20  GLU 20  -34 ?   ?   ?   A . n 
A 1 21  LEU 21  -33 ?   ?   ?   A . n 
A 1 22  GLU 22  -32 ?   ?   ?   A . n 
A 1 23  GLN 23  -31 ?   ?   ?   A . n 
A 1 24  LEU 24  -30 ?   ?   ?   A . n 
A 1 25  ARG 25  -29 ?   ?   ?   A . n 
A 1 26  ALA 26  -28 ?   ?   ?   A . n 
A 1 27  ARG 27  -27 ?   ?   ?   A . n 
A 1 28  LEU 28  -26 ?   ?   ?   A . n 
A 1 29  GLU 29  -25 ?   ?   ?   A . n 
A 1 30  HIS 30  -24 ?   ?   ?   A . n 
A 1 31  HIS 31  -23 ?   ?   ?   A . n 
A 1 32  PRO 32  -22 ?   ?   ?   A . n 
A 1 33  GLN 33  -21 ?   ?   ?   A . n 
A 1 34  GLY 34  -20 ?   ?   ?   A . n 
A 1 35  GLN 35  -19 ?   ?   ?   A . n 
A 1 36  ARG 36  -18 ?   ?   ?   A . n 
A 1 37  GLU 37  -17 ?   ?   ?   A . n 
A 1 38  PRO 38  -16 ?   ?   ?   A . n 
A 1 39  ASP 39  -15 ?   ?   ?   A . n 
A 1 40  TYR 40  -14 ?   ?   ?   A . n 
A 1 41  ASP 41  -13 ?   ?   ?   A . n 
A 1 42  ILE 42  -12 ?   ?   ?   A . n 
A 1 43  PRO 43  -11 ?   ?   ?   A . n 
A 1 44  THR 44  -10 ?   ?   ?   A . n 
A 1 45  THR 45  -9  ?   ?   ?   A . n 
A 1 46  GLU 46  -8  ?   ?   ?   A . n 
A 1 47  ASN 47  -7  ?   ?   ?   A . n 
A 1 48  LEU 48  -6  ?   ?   ?   A . n 
A 1 49  TYR 49  -5  ?   ?   ?   A . n 
A 1 50  PHE 50  -4  ?   ?   ?   A . n 
A 1 51  GLN 51  -3  ?   ?   ?   A . n 
A 1 52  GLY 52  -2  ?   ?   ?   A . n 
A 1 53  THR 53  -1  ?   ?   ?   A . n 
A 1 54  GLY 54  0   ?   ?   ?   A . n 
A 1 55  GLN 55  1   ?   ?   ?   A . n 
A 1 56  SER 56  2   ?   ?   ?   A . n 
A 1 57  VAL 57  3   ?   ?   ?   A . n 
A 1 58  ASN 58  4   4   ASN ASN A . n 
A 1 59  ASP 59  5   5   ASP ASP A . n 
A 1 60  PRO 60  6   6   PRO PRO A . n 
A 1 61  GLY 61  7   7   GLY GLY A . n 
A 1 62  ASN 62  8   8   ASN ASN A . n 
A 1 63  MET 63  9   9   MET MET A . n 
A 1 64  SER 64  10  10  SER SER A . n 
A 1 65  PHE 65  11  11  PHE PHE A . n 
A 1 66  VAL 66  12  12  VAL VAL A . n 
A 1 67  LYS 67  13  13  LYS LYS A . n 
A 1 68  GLU 68  14  14  GLU GLU A . n 
A 1 69  THR 69  15  15  THR THR A . n 
A 1 70  VAL 70  16  16  VAL VAL A . n 
A 1 71  ASP 71  17  17  ASP ASP A . n 
A 1 72  LYS 72  18  18  LYS LYS A . n 
A 1 73  LEU 73  19  19  LEU LEU A . n 
A 1 74  LEU 74  20  20  LEU LEU A . n 
A 1 75  LYS 75  21  21  LYS LYS A . n 
A 1 76  GLY 76  22  22  GLY GLY A . n 
A 1 77  TYR 77  23  23  TYR TYR A . n 
A 1 78  ASP 78  24  24  ASP ASP A . n 
A 1 79  ILE 79  25  25  ILE ILE A . n 
A 1 80  ARG 80  26  26  ARG ARG A . n 
A 1 81  LEU 81  27  27  LEU LEU A . n 
A 1 82  ARG 82  28  28  ARG ARG A . n 
A 1 83  PRO 83  29  29  PRO PRO A . n 
A 1 84  ASP 84  30  30  ASP ASP A . n 
A 1 85  PHE 85  31  31  PHE PHE A . n 
A 1 86  GLY 86  32  32  GLY GLY A . n 
A 1 87  GLY 87  33  33  GLY GLY A . n 
A 1 88  PRO 88  34  34  PRO PRO A . n 
A 1 89  PRO 89  35  35  PRO PRO A . n 
A 1 90  VAL 90  36  36  VAL VAL A . n 
A 1 91  CYS 91  37  37  CYS CYS A . n 
A 1 92  VAL 92  38  38  VAL VAL A . n 
A 1 93  GLY 93  39  39  GLY GLY A . n 
A 1 94  MET 94  40  40  MET MET A . n 
A 1 95  ASN 95  41  41  ASN ASN A . n 
A 1 96  ILE 96  42  42  ILE ILE A . n 
A 1 97  ASP 97  43  43  ASP ASP A . n 
A 1 98  ILE 98  44  44  ILE ILE A . n 
A 1 99  ALA 99  45  45  ALA ALA A . n 
A 1 100 SER 100 46  46  SER SER A . n 
A 1 101 ILE 101 47  47  ILE ILE A . n 
A 1 102 ASP 102 48  48  ASP ASP A . n 
A 1 103 MET 103 49  49  MET MET A . n 
A 1 104 VAL 104 50  50  VAL VAL A . n 
A 1 105 SER 105 51  51  SER SER A . n 
A 1 106 GLU 106 52  52  GLU GLU A . n 
A 1 107 VAL 107 53  53  VAL VAL A . n 
A 1 108 ASN 108 54  54  ASN ASN A . n 
A 1 109 MET 109 55  55  MET MET A . n 
A 1 110 ASP 110 56  56  ASP ASP A . n 
A 1 111 TYR 111 57  57  TYR TYR A . n 
A 1 112 THR 112 58  58  THR THR A . n 
A 1 113 LEU 113 59  59  LEU LEU A . n 
A 1 114 THR 114 60  60  THR THR A . n 
A 1 115 MET 115 61  61  MET MET A . n 
A 1 116 TYR 116 62  62  TYR TYR A . n 
A 1 117 PHE 117 63  63  PHE PHE A . n 
A 1 118 GLN 118 64  64  GLN GLN A . n 
A 1 119 GLN 119 65  65  GLN GLN A . n 
A 1 120 TYR 120 66  66  TYR TYR A . n 
A 1 121 TRP 121 67  67  TRP TRP A . n 
A 1 122 ARG 122 68  68  ARG ARG A . n 
A 1 123 ASP 123 69  69  ASP ASP A . n 
A 1 124 LYS 124 70  70  LYS LYS A . n 
A 1 125 ARG 125 71  71  ARG ARG A . n 
A 1 126 LEU 126 72  72  LEU LEU A . n 
A 1 127 ALA 127 73  73  ALA ALA A . n 
A 1 128 TYR 128 74  74  TYR TYR A . n 
A 1 129 SER 129 75  75  SER SER A . n 
A 1 130 GLY 130 76  76  GLY GLY A . n 
A 1 131 ILE 131 77  77  ILE ILE A . n 
A 1 132 PRO 132 78  78  PRO PRO A . n 
A 1 133 LEU 133 79  79  LEU LEU A . n 
A 1 134 ASN 134 80  80  ASN ASN A . n 
A 1 135 LEU 135 81  81  LEU LEU A . n 
A 1 136 THR 136 82  82  THR THR A . n 
A 1 137 LEU 137 83  83  LEU LEU A . n 
A 1 138 ASP 138 84  84  ASP ASP A . n 
A 1 139 ASN 139 85  85  ASN ASN A . n 
A 1 140 ARG 140 86  86  ARG ARG A . n 
A 1 141 VAL 141 87  87  VAL VAL A . n 
A 1 142 ALA 142 88  88  ALA ALA A . n 
A 1 143 ASP 143 89  89  ASP ASP A . n 
A 1 144 GLN 144 90  90  GLN GLN A . n 
A 1 145 LEU 145 91  91  LEU LEU A . n 
A 1 146 TRP 146 92  92  TRP TRP A . n 
A 1 147 VAL 147 93  93  VAL VAL A . n 
A 1 148 PRO 148 94  94  PRO PRO A . n 
A 1 149 ASP 149 95  95  ASP ASP A . n 
A 1 150 THR 150 96  96  THR THR A . n 
A 1 151 TYR 151 97  97  TYR TYR A . n 
A 1 152 PHE 152 98  98  PHE PHE A . n 
A 1 153 LEU 153 99  99  LEU LEU A . n 
A 1 154 ASN 154 100 100 ASN ASN A . n 
A 1 155 ASP 155 101 101 ASP ASP A . n 
A 1 156 LYS 156 102 102 LYS LYS A . n 
A 1 157 LYS 157 103 103 LYS LYS A . n 
A 1 158 SER 158 104 104 SER SER A . n 
A 1 159 PHE 159 105 105 PHE PHE A . n 
A 1 160 VAL 160 106 106 VAL VAL A . n 
A 1 161 HIS 161 107 107 HIS HIS A . n 
A 1 162 GLY 162 108 108 GLY GLY A . n 
A 1 163 VAL 163 109 109 VAL VAL A . n 
A 1 164 THR 164 110 110 THR THR A . n 
A 1 165 VAL 165 111 111 VAL VAL A . n 
A 1 166 LYS 166 112 112 LYS LYS A . n 
A 1 167 ASN 167 113 113 ASN ASN A . n 
A 1 168 ARG 168 114 114 ARG ARG A . n 
A 1 169 MET 169 115 115 MET MET A . n 
A 1 170 ILE 170 116 116 ILE ILE A . n 
A 1 171 ARG 171 117 117 ARG ARG A . n 
A 1 172 LEU 172 118 118 LEU LEU A . n 
A 1 173 HIS 173 119 119 HIS HIS A . n 
A 1 174 PRO 174 120 120 PRO PRO A . n 
A 1 175 ASP 175 121 121 ASP ASP A . n 
A 1 176 GLY 176 122 122 GLY GLY A . n 
A 1 177 THR 177 123 123 THR THR A . n 
A 1 178 VAL 178 124 124 VAL VAL A . n 
A 1 179 LEU 179 125 125 LEU LEU A . n 
A 1 180 TYR 180 126 126 TYR TYR A . n 
A 1 181 GLY 181 127 127 GLY GLY A . n 
A 1 182 LEU 182 128 128 LEU LEU A . n 
A 1 183 ARG 183 129 129 ARG ARG A . n 
A 1 184 ILE 184 130 130 ILE ILE A . n 
A 1 185 THR 185 131 131 THR THR A . n 
A 1 186 THR 186 132 132 THR THR A . n 
A 1 187 THR 187 133 133 THR THR A . n 
A 1 188 ALA 188 134 134 ALA ALA A . n 
A 1 189 ALA 189 135 135 ALA ALA A . n 
A 1 190 CYS 190 136 136 CYS CYS A . n 
A 1 191 MET 191 137 137 MET MET A . n 
A 1 192 MET 192 138 138 MET MET A . n 
A 1 193 ASP 193 139 139 ASP ASP A . n 
A 1 194 LEU 194 140 140 LEU LEU A . n 
A 1 195 ARG 195 141 141 ARG ARG A . n 
A 1 196 ARG 196 142 142 ARG ARG A . n 
A 1 197 TYR 197 143 143 TYR TYR A . n 
A 1 198 PRO 198 144 144 PRO PRO A . n 
A 1 199 LEU 199 145 145 LEU LEU A . n 
A 1 200 ASP 200 146 146 ASP ASP A . n 
A 1 201 GLU 201 147 147 GLU GLU A . n 
A 1 202 GLN 202 148 148 GLN GLN A . n 
A 1 203 ASN 203 149 149 ASN ASN A . n 
A 1 204 CYS 204 150 150 CYS CYS A . n 
A 1 205 THR 205 151 151 THR THR A . n 
A 1 206 LEU 206 152 152 LEU LEU A . n 
A 1 207 GLU 207 153 153 GLU GLU A . n 
A 1 208 ILE 208 154 154 ILE ILE A . n 
A 1 209 GLU 209 155 155 GLU GLU A . n 
A 1 210 SER 210 156 156 SER SER A . n 
A 1 211 TYR 211 157 157 TYR TYR A . n 
A 1 212 GLY 212 158 158 GLY GLY A . n 
A 1 213 TYR 213 159 159 TYR TYR A . n 
A 1 214 THR 214 160 160 THR THR A . n 
A 1 215 THR 215 161 161 THR THR A . n 
A 1 216 ASP 216 162 162 ASP ASP A . n 
A 1 217 ASP 217 163 163 ASP ASP A . n 
A 1 218 ILE 218 164 164 ILE ILE A . n 
A 1 219 GLU 219 165 165 GLU GLU A . n 
A 1 220 PHE 220 166 166 PHE PHE A . n 
A 1 221 TYR 221 167 167 TYR TYR A . n 
A 1 222 TRP 222 168 168 TRP TRP A . n 
A 1 223 ARG 223 169 169 ARG ARG A . n 
A 1 224 GLY 224 170 170 GLY GLY A . n 
A 1 225 GLY 225 171 171 GLY GLY A . n 
A 1 226 ASP 226 172 172 ASP ASP A . n 
A 1 227 LYS 227 173 173 LYS LYS A . n 
A 1 228 ALA 228 174 174 ALA ALA A . n 
A 1 229 VAL 229 175 175 VAL VAL A . n 
A 1 230 THR 230 176 176 THR THR A . n 
A 1 231 GLY 231 177 177 GLY GLY A . n 
A 1 232 VAL 232 178 178 VAL VAL A . n 
A 1 233 GLU 233 179 179 GLU GLU A . n 
A 1 234 ARG 234 180 180 ARG ARG A . n 
A 1 235 ILE 235 181 181 ILE ILE A . n 
A 1 236 GLU 236 182 182 GLU GLU A . n 
A 1 237 LEU 237 183 183 LEU LEU A . n 
A 1 238 PRO 238 184 184 PRO PRO A . n 
A 1 239 GLN 239 185 185 GLN GLN A . n 
A 1 240 PHE 240 186 186 PHE PHE A . n 
A 1 241 SER 241 187 187 SER SER A . n 
A 1 242 ILE 242 188 188 ILE ILE A . n 
A 1 243 VAL 243 189 189 VAL VAL A . n 
A 1 244 GLU 244 190 190 GLU GLU A . n 
A 1 245 HIS 245 191 191 HIS HIS A . n 
A 1 246 ARG 246 192 192 ARG ARG A . n 
A 1 247 LEU 247 193 193 LEU LEU A . n 
A 1 248 VAL 248 194 194 VAL VAL A . n 
A 1 249 SER 249 195 195 SER SER A . n 
A 1 250 ARG 250 196 196 ARG ARG A . n 
A 1 251 ASN 251 197 197 ASN ASN A . n 
A 1 252 VAL 252 198 198 VAL VAL A . n 
A 1 253 VAL 253 199 199 VAL VAL A . n 
A 1 254 PHE 254 200 200 PHE PHE A . n 
A 1 255 ALA 255 201 201 ALA ALA A . n 
A 1 256 THR 256 202 202 THR THR A . n 
A 1 257 GLY 257 203 203 GLY GLY A . n 
A 1 258 ALA 258 204 204 ALA ALA A . n 
A 1 259 TYR 259 205 205 TYR TYR A . n 
A 1 260 PRO 260 206 206 PRO PRO A . n 
A 1 261 ARG 261 207 207 ARG ARG A . n 
A 1 262 LEU 262 208 208 LEU LEU A . n 
A 1 263 SER 263 209 209 SER SER A . n 
A 1 264 LEU 264 210 210 LEU LEU A . n 
A 1 265 SER 265 211 211 SER SER A . n 
A 1 266 PHE 266 212 212 PHE PHE A . n 
A 1 267 ARG 267 213 213 ARG ARG A . n 
A 1 268 LEU 268 214 214 LEU LEU A . n 
A 1 269 LYS 269 215 215 LYS LYS A . n 
A 1 270 ARG 270 216 216 ARG ARG A . n 
A 1 271 ASN 271 217 217 ASN ASN A . n 
A 1 272 ILE 272 218 218 ILE ILE A . n 
A 1 273 GLY 273 219 219 GLY GLY A . n 
A 1 274 TYR 274 220 220 TYR TYR A . n 
A 1 275 PHE 275 221 221 PHE PHE A . n 
A 1 276 ILE 276 222 222 ILE ILE A . n 
A 1 277 LEU 277 223 223 LEU LEU A . n 
A 1 278 GLN 278 224 224 GLN GLN A . n 
A 1 279 THR 279 225 225 THR THR A . n 
A 1 280 TYR 280 226 226 TYR TYR A . n 
A 1 281 MET 281 227 227 MET MET A . n 
A 1 282 PRO 282 228 228 PRO PRO A . n 
A 1 283 SER 283 229 229 SER SER A . n 
A 1 284 ILE 284 230 230 ILE ILE A . n 
A 1 285 LEU 285 231 231 LEU LEU A . n 
A 1 286 ILE 286 232 232 ILE ILE A . n 
A 1 287 THR 287 233 233 THR THR A . n 
A 1 288 ILE 288 234 234 ILE ILE A . n 
A 1 289 LEU 289 235 235 LEU LEU A . n 
A 1 290 SER 290 236 236 SER SER A . n 
A 1 291 TRP 291 237 237 TRP TRP A . n 
A 1 292 VAL 292 238 238 VAL VAL A . n 
A 1 293 SER 293 239 239 SER SER A . n 
A 1 294 PHE 294 240 240 PHE PHE A . n 
A 1 295 TRP 295 241 241 TRP TRP A . n 
A 1 296 ILE 296 242 242 ILE ILE A . n 
A 1 297 ASN 297 243 243 ASN ASN A . n 
A 1 298 TYR 298 244 244 TYR TYR A . n 
A 1 299 ASP 299 245 245 ASP ASP A . n 
A 1 300 ALA 300 246 246 ALA ALA A . n 
A 1 301 SER 301 247 247 SER SER A . n 
A 1 302 ALA 302 248 248 ALA ALA A . n 
A 1 303 ALA 303 249 249 ALA ALA A . n 
A 1 304 ARG 304 250 250 ARG ARG A . n 
A 1 305 VAL 305 251 251 VAL VAL A . n 
A 1 306 ALA 306 252 252 ALA ALA A . n 
A 1 307 LEU 307 253 253 LEU LEU A . n 
A 1 308 GLY 308 254 254 GLY GLY A . n 
A 1 309 ILE 309 255 255 ILE ILE A . n 
A 1 310 THR 310 256 256 THR THR A . n 
A 1 311 THR 311 257 257 THR THR A . n 
A 1 312 VAL 312 258 258 VAL VAL A . n 
A 1 313 LEU 313 259 259 LEU LEU A . n 
A 1 314 THR 314 260 260 THR THR A . n 
A 1 315 MET 315 261 261 MET MET A . n 
A 1 316 THR 316 262 262 THR THR A . n 
A 1 317 THR 317 263 263 THR THR A . n 
A 1 318 ILE 318 264 264 ILE ILE A . n 
A 1 319 ASN 319 265 265 ASN ASN A . n 
A 1 320 THR 320 266 266 THR THR A . n 
A 1 321 HIS 321 267 267 HIS HIS A . n 
A 1 322 LEU 322 268 268 LEU LEU A . n 
A 1 323 ARG 323 269 269 ARG ARG A . n 
A 1 324 GLU 324 270 270 GLU GLU A . n 
A 1 325 THR 325 271 271 THR THR A . n 
A 1 326 LEU 326 272 272 LEU LEU A . n 
A 1 327 PRO 327 273 273 PRO PRO A . n 
A 1 328 LYS 328 274 274 LYS LYS A . n 
A 1 329 ILE 329 275 275 ILE ILE A . n 
A 1 330 PRO 330 276 276 PRO PRO A . n 
A 1 331 TYR 331 277 277 TYR TYR A . n 
A 1 332 VAL 332 278 278 VAL VAL A . n 
A 1 333 LYS 333 279 279 LYS LYS A . n 
A 1 334 ALA 334 280 280 ALA ALA A . n 
A 1 335 ILE 335 281 281 ILE ILE A . n 
A 1 336 ASP 336 282 282 ASP ASP A . n 
A 1 337 MET 337 283 283 MET MET A . n 
A 1 338 TYR 338 284 284 TYR TYR A . n 
A 1 339 LEU 339 285 285 LEU LEU A . n 
A 1 340 MET 340 286 286 MET MET A . n 
A 1 341 GLY 341 287 287 GLY GLY A . n 
A 1 342 CYS 342 288 288 CYS CYS A . n 
A 1 343 PHE 343 289 289 PHE PHE A . n 
A 1 344 VAL 344 290 290 VAL VAL A . n 
A 1 345 PHE 345 291 291 PHE PHE A . n 
A 1 346 VAL 346 292 292 VAL VAL A . n 
A 1 347 PHE 347 293 293 PHE PHE A . n 
A 1 348 LEU 348 294 294 LEU LEU A . n 
A 1 349 ALA 349 295 295 ALA ALA A . n 
A 1 350 LEU 350 296 296 LEU LEU A . n 
A 1 351 LEU 351 297 297 LEU LEU A . n 
A 1 352 GLU 352 298 298 GLU GLU A . n 
A 1 353 TYR 353 299 299 TYR TYR A . n 
A 1 354 ALA 354 300 300 ALA ALA A . n 
A 1 355 PHE 355 301 301 PHE PHE A . n 
A 1 356 VAL 356 302 302 VAL VAL A . n 
A 1 357 ASN 357 303 303 ASN ASN A . n 
A 1 358 TYR 358 304 304 TYR TYR A . n 
A 1 359 ILE 359 305 305 ILE ILE A . n 
A 1 360 PHE 360 306 306 PHE PHE A . n 
A 1 361 PHE 361 307 307 PHE PHE A . n 
A 1 362 SER 362 308 308 SER SER A . n 
A 1 363 GLN 363 309 309 GLN GLN A . n 
A 1 364 PRO 364 310 310 PRO PRO A . n 
A 1 365 ALA 365 311 311 ALA ALA A . n 
A 1 366 ARG 366 312 312 ARG ARG A . n 
A 1 367 ALA 367 313 313 ALA ALA A . n 
A 1 368 ALA 368 314 314 ALA ALA A . n 
A 1 369 ALA 369 422 422 ALA ALA A . n 
A 1 370 ILE 370 423 423 ILE ILE A . n 
A 1 371 ASP 371 424 424 ASP ASP A . n 
A 1 372 ARG 372 425 425 ARG ARG A . n 
A 1 373 TRP 373 426 426 TRP TRP A . n 
A 1 374 SER 374 427 427 SER SER A . n 
A 1 375 ARG 375 428 428 ARG ARG A . n 
A 1 376 ILE 376 429 429 ILE ILE A . n 
A 1 377 VAL 377 430 430 VAL VAL A . n 
A 1 378 PHE 378 431 431 PHE PHE A . n 
A 1 379 PRO 379 432 432 PRO PRO A . n 
A 1 380 PHE 380 433 433 PHE PHE A . n 
A 1 381 THR 381 434 434 THR THR A . n 
A 1 382 PHE 382 435 435 PHE PHE A . n 
A 1 383 SER 383 436 436 SER SER A . n 
A 1 384 LEU 384 437 437 LEU LEU A . n 
A 1 385 PHE 385 438 438 PHE PHE A . n 
A 1 386 ASN 386 439 439 ASN ASN A . n 
A 1 387 LEU 387 440 440 LEU LEU A . n 
A 1 388 VAL 388 441 441 VAL VAL A . n 
A 1 389 TYR 389 442 442 TYR TYR A . n 
A 1 390 TRP 390 443 443 TRP TRP A . n 
A 1 391 LEU 391 444 444 LEU LEU A . n 
A 1 392 TYR 392 445 445 TYR TYR A . n 
A 1 393 TYR 393 446 446 TYR TYR A . n 
A 1 394 VAL 394 447 447 VAL VAL A . n 
A 1 395 ASN 395 448 ?   ?   ?   A . n 
B 1 1   MET 1   -53 ?   ?   ?   B . n 
B 1 2   ASP 2   -52 ?   ?   ?   B . n 
B 1 3   GLU 3   -51 ?   ?   ?   B . n 
B 1 4   LYS 4   -50 ?   ?   ?   B . n 
B 1 5   THR 5   -49 ?   ?   ?   B . n 
B 1 6   THR 6   -48 ?   ?   ?   B . n 
B 1 7   GLY 7   -47 ?   ?   ?   B . n 
B 1 8   TRP 8   -46 ?   ?   ?   B . n 
B 1 9   ARG 9   -45 ?   ?   ?   B . n 
B 1 10  GLY 10  -44 ?   ?   ?   B . n 
B 1 11  GLY 11  -43 ?   ?   ?   B . n 
B 1 12  HIS 12  -42 ?   ?   ?   B . n 
B 1 13  VAL 13  -41 ?   ?   ?   B . n 
B 1 14  VAL 14  -40 ?   ?   ?   B . n 
B 1 15  GLU 15  -39 ?   ?   ?   B . n 
B 1 16  GLY 16  -38 ?   ?   ?   B . n 
B 1 17  LEU 17  -37 ?   ?   ?   B . n 
B 1 18  ALA 18  -36 ?   ?   ?   B . n 
B 1 19  GLY 19  -35 ?   ?   ?   B . n 
B 1 20  GLU 20  -34 ?   ?   ?   B . n 
B 1 21  LEU 21  -33 ?   ?   ?   B . n 
B 1 22  GLU 22  -32 ?   ?   ?   B . n 
B 1 23  GLN 23  -31 ?   ?   ?   B . n 
B 1 24  LEU 24  -30 ?   ?   ?   B . n 
B 1 25  ARG 25  -29 ?   ?   ?   B . n 
B 1 26  ALA 26  -28 ?   ?   ?   B . n 
B 1 27  ARG 27  -27 ?   ?   ?   B . n 
B 1 28  LEU 28  -26 ?   ?   ?   B . n 
B 1 29  GLU 29  -25 ?   ?   ?   B . n 
B 1 30  HIS 30  -24 ?   ?   ?   B . n 
B 1 31  HIS 31  -23 ?   ?   ?   B . n 
B 1 32  PRO 32  -22 ?   ?   ?   B . n 
B 1 33  GLN 33  -21 ?   ?   ?   B . n 
B 1 34  GLY 34  -20 ?   ?   ?   B . n 
B 1 35  GLN 35  -19 ?   ?   ?   B . n 
B 1 36  ARG 36  -18 ?   ?   ?   B . n 
B 1 37  GLU 37  -17 ?   ?   ?   B . n 
B 1 38  PRO 38  -16 ?   ?   ?   B . n 
B 1 39  ASP 39  -15 ?   ?   ?   B . n 
B 1 40  TYR 40  -14 ?   ?   ?   B . n 
B 1 41  ASP 41  -13 ?   ?   ?   B . n 
B 1 42  ILE 42  -12 ?   ?   ?   B . n 
B 1 43  PRO 43  -11 ?   ?   ?   B . n 
B 1 44  THR 44  -10 ?   ?   ?   B . n 
B 1 45  THR 45  -9  ?   ?   ?   B . n 
B 1 46  GLU 46  -8  ?   ?   ?   B . n 
B 1 47  ASN 47  -7  ?   ?   ?   B . n 
B 1 48  LEU 48  -6  ?   ?   ?   B . n 
B 1 49  TYR 49  -5  ?   ?   ?   B . n 
B 1 50  PHE 50  -4  ?   ?   ?   B . n 
B 1 51  GLN 51  -3  ?   ?   ?   B . n 
B 1 52  GLY 52  -2  ?   ?   ?   B . n 
B 1 53  THR 53  -1  ?   ?   ?   B . n 
B 1 54  GLY 54  0   ?   ?   ?   B . n 
B 1 55  GLN 55  1   ?   ?   ?   B . n 
B 1 56  SER 56  2   ?   ?   ?   B . n 
B 1 57  VAL 57  3   ?   ?   ?   B . n 
B 1 58  ASN 58  4   4   ASN ASN B . n 
B 1 59  ASP 59  5   5   ASP ASP B . n 
B 1 60  PRO 60  6   6   PRO PRO B . n 
B 1 61  GLY 61  7   7   GLY GLY B . n 
B 1 62  ASN 62  8   8   ASN ASN B . n 
B 1 63  MET 63  9   9   MET MET B . n 
B 1 64  SER 64  10  10  SER SER B . n 
B 1 65  PHE 65  11  11  PHE PHE B . n 
B 1 66  VAL 66  12  12  VAL VAL B . n 
B 1 67  LYS 67  13  13  LYS LYS B . n 
B 1 68  GLU 68  14  14  GLU GLU B . n 
B 1 69  THR 69  15  15  THR THR B . n 
B 1 70  VAL 70  16  16  VAL VAL B . n 
B 1 71  ASP 71  17  17  ASP ASP B . n 
B 1 72  LYS 72  18  18  LYS LYS B . n 
B 1 73  LEU 73  19  19  LEU LEU B . n 
B 1 74  LEU 74  20  20  LEU LEU B . n 
B 1 75  LYS 75  21  21  LYS LYS B . n 
B 1 76  GLY 76  22  22  GLY GLY B . n 
B 1 77  TYR 77  23  23  TYR TYR B . n 
B 1 78  ASP 78  24  24  ASP ASP B . n 
B 1 79  ILE 79  25  25  ILE ILE B . n 
B 1 80  ARG 80  26  26  ARG ARG B . n 
B 1 81  LEU 81  27  27  LEU LEU B . n 
B 1 82  ARG 82  28  28  ARG ARG B . n 
B 1 83  PRO 83  29  29  PRO PRO B . n 
B 1 84  ASP 84  30  30  ASP ASP B . n 
B 1 85  PHE 85  31  31  PHE PHE B . n 
B 1 86  GLY 86  32  32  GLY GLY B . n 
B 1 87  GLY 87  33  33  GLY GLY B . n 
B 1 88  PRO 88  34  34  PRO PRO B . n 
B 1 89  PRO 89  35  35  PRO PRO B . n 
B 1 90  VAL 90  36  36  VAL VAL B . n 
B 1 91  CYS 91  37  37  CYS CYS B . n 
B 1 92  VAL 92  38  38  VAL VAL B . n 
B 1 93  GLY 93  39  39  GLY GLY B . n 
B 1 94  MET 94  40  40  MET MET B . n 
B 1 95  ASN 95  41  41  ASN ASN B . n 
B 1 96  ILE 96  42  42  ILE ILE B . n 
B 1 97  ASP 97  43  43  ASP ASP B . n 
B 1 98  ILE 98  44  44  ILE ILE B . n 
B 1 99  ALA 99  45  45  ALA ALA B . n 
B 1 100 SER 100 46  46  SER SER B . n 
B 1 101 ILE 101 47  47  ILE ILE B . n 
B 1 102 ASP 102 48  48  ASP ASP B . n 
B 1 103 MET 103 49  49  MET MET B . n 
B 1 104 VAL 104 50  50  VAL VAL B . n 
B 1 105 SER 105 51  51  SER SER B . n 
B 1 106 GLU 106 52  52  GLU GLU B . n 
B 1 107 VAL 107 53  53  VAL VAL B . n 
B 1 108 ASN 108 54  54  ASN ASN B . n 
B 1 109 MET 109 55  55  MET MET B . n 
B 1 110 ASP 110 56  56  ASP ASP B . n 
B 1 111 TYR 111 57  57  TYR TYR B . n 
B 1 112 THR 112 58  58  THR THR B . n 
B 1 113 LEU 113 59  59  LEU LEU B . n 
B 1 114 THR 114 60  60  THR THR B . n 
B 1 115 MET 115 61  61  MET MET B . n 
B 1 116 TYR 116 62  62  TYR TYR B . n 
B 1 117 PHE 117 63  63  PHE PHE B . n 
B 1 118 GLN 118 64  64  GLN GLN B . n 
B 1 119 GLN 119 65  65  GLN GLN B . n 
B 1 120 TYR 120 66  66  TYR TYR B . n 
B 1 121 TRP 121 67  67  TRP TRP B . n 
B 1 122 ARG 122 68  68  ARG ARG B . n 
B 1 123 ASP 123 69  69  ASP ASP B . n 
B 1 124 LYS 124 70  70  LYS LYS B . n 
B 1 125 ARG 125 71  71  ARG ARG B . n 
B 1 126 LEU 126 72  72  LEU LEU B . n 
B 1 127 ALA 127 73  73  ALA ALA B . n 
B 1 128 TYR 128 74  74  TYR TYR B . n 
B 1 129 SER 129 75  75  SER SER B . n 
B 1 130 GLY 130 76  76  GLY GLY B . n 
B 1 131 ILE 131 77  77  ILE ILE B . n 
B 1 132 PRO 132 78  78  PRO PRO B . n 
B 1 133 LEU 133 79  79  LEU LEU B . n 
B 1 134 ASN 134 80  80  ASN ASN B . n 
B 1 135 LEU 135 81  81  LEU LEU B . n 
B 1 136 THR 136 82  82  THR THR B . n 
B 1 137 LEU 137 83  83  LEU LEU B . n 
B 1 138 ASP 138 84  84  ASP ASP B . n 
B 1 139 ASN 139 85  85  ASN ASN B . n 
B 1 140 ARG 140 86  86  ARG ARG B . n 
B 1 141 VAL 141 87  87  VAL VAL B . n 
B 1 142 ALA 142 88  88  ALA ALA B . n 
B 1 143 ASP 143 89  89  ASP ASP B . n 
B 1 144 GLN 144 90  90  GLN GLN B . n 
B 1 145 LEU 145 91  91  LEU LEU B . n 
B 1 146 TRP 146 92  92  TRP TRP B . n 
B 1 147 VAL 147 93  93  VAL VAL B . n 
B 1 148 PRO 148 94  94  PRO PRO B . n 
B 1 149 ASP 149 95  95  ASP ASP B . n 
B 1 150 THR 150 96  96  THR THR B . n 
B 1 151 TYR 151 97  97  TYR TYR B . n 
B 1 152 PHE 152 98  98  PHE PHE B . n 
B 1 153 LEU 153 99  99  LEU LEU B . n 
B 1 154 ASN 154 100 100 ASN ASN B . n 
B 1 155 ASP 155 101 101 ASP ASP B . n 
B 1 156 LYS 156 102 102 LYS LYS B . n 
B 1 157 LYS 157 103 103 LYS LYS B . n 
B 1 158 SER 158 104 104 SER SER B . n 
B 1 159 PHE 159 105 105 PHE PHE B . n 
B 1 160 VAL 160 106 106 VAL VAL B . n 
B 1 161 HIS 161 107 107 HIS HIS B . n 
B 1 162 GLY 162 108 108 GLY GLY B . n 
B 1 163 VAL 163 109 109 VAL VAL B . n 
B 1 164 THR 164 110 110 THR THR B . n 
B 1 165 VAL 165 111 111 VAL VAL B . n 
B 1 166 LYS 166 112 112 LYS LYS B . n 
B 1 167 ASN 167 113 113 ASN ASN B . n 
B 1 168 ARG 168 114 114 ARG ARG B . n 
B 1 169 MET 169 115 115 MET MET B . n 
B 1 170 ILE 170 116 116 ILE ILE B . n 
B 1 171 ARG 171 117 117 ARG ARG B . n 
B 1 172 LEU 172 118 118 LEU LEU B . n 
B 1 173 HIS 173 119 119 HIS HIS B . n 
B 1 174 PRO 174 120 120 PRO PRO B . n 
B 1 175 ASP 175 121 121 ASP ASP B . n 
B 1 176 GLY 176 122 122 GLY GLY B . n 
B 1 177 THR 177 123 123 THR THR B . n 
B 1 178 VAL 178 124 124 VAL VAL B . n 
B 1 179 LEU 179 125 125 LEU LEU B . n 
B 1 180 TYR 180 126 126 TYR TYR B . n 
B 1 181 GLY 181 127 127 GLY GLY B . n 
B 1 182 LEU 182 128 128 LEU LEU B . n 
B 1 183 ARG 183 129 129 ARG ARG B . n 
B 1 184 ILE 184 130 130 ILE ILE B . n 
B 1 185 THR 185 131 131 THR THR B . n 
B 1 186 THR 186 132 132 THR THR B . n 
B 1 187 THR 187 133 133 THR THR B . n 
B 1 188 ALA 188 134 134 ALA ALA B . n 
B 1 189 ALA 189 135 135 ALA ALA B . n 
B 1 190 CYS 190 136 136 CYS CYS B . n 
B 1 191 MET 191 137 137 MET MET B . n 
B 1 192 MET 192 138 138 MET MET B . n 
B 1 193 ASP 193 139 139 ASP ASP B . n 
B 1 194 LEU 194 140 140 LEU LEU B . n 
B 1 195 ARG 195 141 141 ARG ARG B . n 
B 1 196 ARG 196 142 142 ARG ARG B . n 
B 1 197 TYR 197 143 143 TYR TYR B . n 
B 1 198 PRO 198 144 144 PRO PRO B . n 
B 1 199 LEU 199 145 145 LEU LEU B . n 
B 1 200 ASP 200 146 146 ASP ASP B . n 
B 1 201 GLU 201 147 147 GLU GLU B . n 
B 1 202 GLN 202 148 148 GLN GLN B . n 
B 1 203 ASN 203 149 149 ASN ASN B . n 
B 1 204 CYS 204 150 150 CYS CYS B . n 
B 1 205 THR 205 151 151 THR THR B . n 
B 1 206 LEU 206 152 152 LEU LEU B . n 
B 1 207 GLU 207 153 153 GLU GLU B . n 
B 1 208 ILE 208 154 154 ILE ILE B . n 
B 1 209 GLU 209 155 155 GLU GLU B . n 
B 1 210 SER 210 156 156 SER SER B . n 
B 1 211 TYR 211 157 157 TYR TYR B . n 
B 1 212 GLY 212 158 158 GLY GLY B . n 
B 1 213 TYR 213 159 159 TYR TYR B . n 
B 1 214 THR 214 160 160 THR THR B . n 
B 1 215 THR 215 161 161 THR THR B . n 
B 1 216 ASP 216 162 162 ASP ASP B . n 
B 1 217 ASP 217 163 163 ASP ASP B . n 
B 1 218 ILE 218 164 164 ILE ILE B . n 
B 1 219 GLU 219 165 165 GLU GLU B . n 
B 1 220 PHE 220 166 166 PHE PHE B . n 
B 1 221 TYR 221 167 167 TYR TYR B . n 
B 1 222 TRP 222 168 168 TRP TRP B . n 
B 1 223 ARG 223 169 169 ARG ARG B . n 
B 1 224 GLY 224 170 170 GLY GLY B . n 
B 1 225 GLY 225 171 171 GLY GLY B . n 
B 1 226 ASP 226 172 172 ASP ASP B . n 
B 1 227 LYS 227 173 173 LYS LYS B . n 
B 1 228 ALA 228 174 174 ALA ALA B . n 
B 1 229 VAL 229 175 175 VAL VAL B . n 
B 1 230 THR 230 176 176 THR THR B . n 
B 1 231 GLY 231 177 177 GLY GLY B . n 
B 1 232 VAL 232 178 178 VAL VAL B . n 
B 1 233 GLU 233 179 179 GLU GLU B . n 
B 1 234 ARG 234 180 180 ARG ARG B . n 
B 1 235 ILE 235 181 181 ILE ILE B . n 
B 1 236 GLU 236 182 182 GLU GLU B . n 
B 1 237 LEU 237 183 183 LEU LEU B . n 
B 1 238 PRO 238 184 184 PRO PRO B . n 
B 1 239 GLN 239 185 185 GLN GLN B . n 
B 1 240 PHE 240 186 186 PHE PHE B . n 
B 1 241 SER 241 187 187 SER SER B . n 
B 1 242 ILE 242 188 188 ILE ILE B . n 
B 1 243 VAL 243 189 189 VAL VAL B . n 
B 1 244 GLU 244 190 190 GLU GLU B . n 
B 1 245 HIS 245 191 191 HIS HIS B . n 
B 1 246 ARG 246 192 192 ARG ARG B . n 
B 1 247 LEU 247 193 193 LEU LEU B . n 
B 1 248 VAL 248 194 194 VAL VAL B . n 
B 1 249 SER 249 195 195 SER SER B . n 
B 1 250 ARG 250 196 196 ARG ARG B . n 
B 1 251 ASN 251 197 197 ASN ASN B . n 
B 1 252 VAL 252 198 198 VAL VAL B . n 
B 1 253 VAL 253 199 199 VAL VAL B . n 
B 1 254 PHE 254 200 200 PHE PHE B . n 
B 1 255 ALA 255 201 201 ALA ALA B . n 
B 1 256 THR 256 202 202 THR THR B . n 
B 1 257 GLY 257 203 203 GLY GLY B . n 
B 1 258 ALA 258 204 204 ALA ALA B . n 
B 1 259 TYR 259 205 205 TYR TYR B . n 
B 1 260 PRO 260 206 206 PRO PRO B . n 
B 1 261 ARG 261 207 207 ARG ARG B . n 
B 1 262 LEU 262 208 208 LEU LEU B . n 
B 1 263 SER 263 209 209 SER SER B . n 
B 1 264 LEU 264 210 210 LEU LEU B . n 
B 1 265 SER 265 211 211 SER SER B . n 
B 1 266 PHE 266 212 212 PHE PHE B . n 
B 1 267 ARG 267 213 213 ARG ARG B . n 
B 1 268 LEU 268 214 214 LEU LEU B . n 
B 1 269 LYS 269 215 215 LYS LYS B . n 
B 1 270 ARG 270 216 216 ARG ARG B . n 
B 1 271 ASN 271 217 217 ASN ASN B . n 
B 1 272 ILE 272 218 218 ILE ILE B . n 
B 1 273 GLY 273 219 219 GLY GLY B . n 
B 1 274 TYR 274 220 220 TYR TYR B . n 
B 1 275 PHE 275 221 221 PHE PHE B . n 
B 1 276 ILE 276 222 222 ILE ILE B . n 
B 1 277 LEU 277 223 223 LEU LEU B . n 
B 1 278 GLN 278 224 224 GLN GLN B . n 
B 1 279 THR 279 225 225 THR THR B . n 
B 1 280 TYR 280 226 226 TYR TYR B . n 
B 1 281 MET 281 227 227 MET MET B . n 
B 1 282 PRO 282 228 228 PRO PRO B . n 
B 1 283 SER 283 229 229 SER SER B . n 
B 1 284 ILE 284 230 230 ILE ILE B . n 
B 1 285 LEU 285 231 231 LEU LEU B . n 
B 1 286 ILE 286 232 232 ILE ILE B . n 
B 1 287 THR 287 233 233 THR THR B . n 
B 1 288 ILE 288 234 234 ILE ILE B . n 
B 1 289 LEU 289 235 235 LEU LEU B . n 
B 1 290 SER 290 236 236 SER SER B . n 
B 1 291 TRP 291 237 237 TRP TRP B . n 
B 1 292 VAL 292 238 238 VAL VAL B . n 
B 1 293 SER 293 239 239 SER SER B . n 
B 1 294 PHE 294 240 240 PHE PHE B . n 
B 1 295 TRP 295 241 241 TRP TRP B . n 
B 1 296 ILE 296 242 242 ILE ILE B . n 
B 1 297 ASN 297 243 243 ASN ASN B . n 
B 1 298 TYR 298 244 244 TYR TYR B . n 
B 1 299 ASP 299 245 245 ASP ASP B . n 
B 1 300 ALA 300 246 246 ALA ALA B . n 
B 1 301 SER 301 247 247 SER SER B . n 
B 1 302 ALA 302 248 248 ALA ALA B . n 
B 1 303 ALA 303 249 249 ALA ALA B . n 
B 1 304 ARG 304 250 250 ARG ARG B . n 
B 1 305 VAL 305 251 251 VAL VAL B . n 
B 1 306 ALA 306 252 252 ALA ALA B . n 
B 1 307 LEU 307 253 253 LEU LEU B . n 
B 1 308 GLY 308 254 254 GLY GLY B . n 
B 1 309 ILE 309 255 255 ILE ILE B . n 
B 1 310 THR 310 256 256 THR THR B . n 
B 1 311 THR 311 257 257 THR THR B . n 
B 1 312 VAL 312 258 258 VAL VAL B . n 
B 1 313 LEU 313 259 259 LEU LEU B . n 
B 1 314 THR 314 260 260 THR THR B . n 
B 1 315 MET 315 261 261 MET MET B . n 
B 1 316 THR 316 262 262 THR THR B . n 
B 1 317 THR 317 263 263 THR THR B . n 
B 1 318 ILE 318 264 264 ILE ILE B . n 
B 1 319 ASN 319 265 265 ASN ASN B . n 
B 1 320 THR 320 266 266 THR THR B . n 
B 1 321 HIS 321 267 267 HIS HIS B . n 
B 1 322 LEU 322 268 268 LEU LEU B . n 
B 1 323 ARG 323 269 269 ARG ARG B . n 
B 1 324 GLU 324 270 270 GLU GLU B . n 
B 1 325 THR 325 271 271 THR THR B . n 
B 1 326 LEU 326 272 272 LEU LEU B . n 
B 1 327 PRO 327 273 273 PRO PRO B . n 
B 1 328 LYS 328 274 274 LYS LYS B . n 
B 1 329 ILE 329 275 275 ILE ILE B . n 
B 1 330 PRO 330 276 276 PRO PRO B . n 
B 1 331 TYR 331 277 277 TYR TYR B . n 
B 1 332 VAL 332 278 278 VAL VAL B . n 
B 1 333 LYS 333 279 279 LYS LYS B . n 
B 1 334 ALA 334 280 280 ALA ALA B . n 
B 1 335 ILE 335 281 281 ILE ILE B . n 
B 1 336 ASP 336 282 282 ASP ASP B . n 
B 1 337 MET 337 283 283 MET MET B . n 
B 1 338 TYR 338 284 284 TYR TYR B . n 
B 1 339 LEU 339 285 285 LEU LEU B . n 
B 1 340 MET 340 286 286 MET MET B . n 
B 1 341 GLY 341 287 287 GLY GLY B . n 
B 1 342 CYS 342 288 288 CYS CYS B . n 
B 1 343 PHE 343 289 289 PHE PHE B . n 
B 1 344 VAL 344 290 290 VAL VAL B . n 
B 1 345 PHE 345 291 291 PHE PHE B . n 
B 1 346 VAL 346 292 292 VAL VAL B . n 
B 1 347 PHE 347 293 293 PHE PHE B . n 
B 1 348 LEU 348 294 294 LEU LEU B . n 
B 1 349 ALA 349 295 295 ALA ALA B . n 
B 1 350 LEU 350 296 296 LEU LEU B . n 
B 1 351 LEU 351 297 297 LEU LEU B . n 
B 1 352 GLU 352 298 298 GLU GLU B . n 
B 1 353 TYR 353 299 299 TYR TYR B . n 
B 1 354 ALA 354 300 300 ALA ALA B . n 
B 1 355 PHE 355 301 301 PHE PHE B . n 
B 1 356 VAL 356 302 302 VAL VAL B . n 
B 1 357 ASN 357 303 303 ASN ASN B . n 
B 1 358 TYR 358 304 304 TYR TYR B . n 
B 1 359 ILE 359 305 305 ILE ILE B . n 
B 1 360 PHE 360 306 306 PHE PHE B . n 
B 1 361 PHE 361 307 307 PHE PHE B . n 
B 1 362 SER 362 308 308 SER SER B . n 
B 1 363 GLN 363 309 309 GLN GLN B . n 
B 1 364 PRO 364 310 310 PRO PRO B . n 
B 1 365 ALA 365 311 311 ALA ALA B . n 
B 1 366 ARG 366 312 312 ARG ARG B . n 
B 1 367 ALA 367 313 313 ALA ALA B . n 
B 1 368 ALA 368 314 314 ALA ALA B . n 
B 1 369 ALA 369 422 422 ALA ALA B . n 
B 1 370 ILE 370 423 423 ILE ILE B . n 
B 1 371 ASP 371 424 424 ASP ASP B . n 
B 1 372 ARG 372 425 425 ARG ARG B . n 
B 1 373 TRP 373 426 426 TRP TRP B . n 
B 1 374 SER 374 427 427 SER SER B . n 
B 1 375 ARG 375 428 428 ARG ARG B . n 
B 1 376 ILE 376 429 429 ILE ILE B . n 
B 1 377 VAL 377 430 430 VAL VAL B . n 
B 1 378 PHE 378 431 431 PHE PHE B . n 
B 1 379 PRO 379 432 432 PRO PRO B . n 
B 1 380 PHE 380 433 433 PHE PHE B . n 
B 1 381 THR 381 434 434 THR THR B . n 
B 1 382 PHE 382 435 435 PHE PHE B . n 
B 1 383 SER 383 436 436 SER SER B . n 
B 1 384 LEU 384 437 437 LEU LEU B . n 
B 1 385 PHE 385 438 438 PHE PHE B . n 
B 1 386 ASN 386 439 439 ASN ASN B . n 
B 1 387 LEU 387 440 440 LEU LEU B . n 
B 1 388 VAL 388 441 441 VAL VAL B . n 
B 1 389 TYR 389 442 442 TYR TYR B . n 
B 1 390 TRP 390 443 443 TRP TRP B . n 
B 1 391 LEU 391 444 444 LEU LEU B . n 
B 1 392 TYR 392 445 445 TYR TYR B . n 
B 1 393 TYR 393 446 446 TYR TYR B . n 
B 1 394 VAL 394 447 447 VAL VAL B . n 
B 1 395 ASN 395 448 ?   ?   ?   B . n 
C 1 1   MET 1   -53 ?   ?   ?   C . n 
C 1 2   ASP 2   -52 ?   ?   ?   C . n 
C 1 3   GLU 3   -51 ?   ?   ?   C . n 
C 1 4   LYS 4   -50 ?   ?   ?   C . n 
C 1 5   THR 5   -49 ?   ?   ?   C . n 
C 1 6   THR 6   -48 ?   ?   ?   C . n 
C 1 7   GLY 7   -47 ?   ?   ?   C . n 
C 1 8   TRP 8   -46 ?   ?   ?   C . n 
C 1 9   ARG 9   -45 ?   ?   ?   C . n 
C 1 10  GLY 10  -44 ?   ?   ?   C . n 
C 1 11  GLY 11  -43 ?   ?   ?   C . n 
C 1 12  HIS 12  -42 ?   ?   ?   C . n 
C 1 13  VAL 13  -41 ?   ?   ?   C . n 
C 1 14  VAL 14  -40 ?   ?   ?   C . n 
C 1 15  GLU 15  -39 ?   ?   ?   C . n 
C 1 16  GLY 16  -38 ?   ?   ?   C . n 
C 1 17  LEU 17  -37 ?   ?   ?   C . n 
C 1 18  ALA 18  -36 ?   ?   ?   C . n 
C 1 19  GLY 19  -35 ?   ?   ?   C . n 
C 1 20  GLU 20  -34 ?   ?   ?   C . n 
C 1 21  LEU 21  -33 ?   ?   ?   C . n 
C 1 22  GLU 22  -32 ?   ?   ?   C . n 
C 1 23  GLN 23  -31 ?   ?   ?   C . n 
C 1 24  LEU 24  -30 ?   ?   ?   C . n 
C 1 25  ARG 25  -29 ?   ?   ?   C . n 
C 1 26  ALA 26  -28 ?   ?   ?   C . n 
C 1 27  ARG 27  -27 ?   ?   ?   C . n 
C 1 28  LEU 28  -26 ?   ?   ?   C . n 
C 1 29  GLU 29  -25 ?   ?   ?   C . n 
C 1 30  HIS 30  -24 ?   ?   ?   C . n 
C 1 31  HIS 31  -23 ?   ?   ?   C . n 
C 1 32  PRO 32  -22 ?   ?   ?   C . n 
C 1 33  GLN 33  -21 ?   ?   ?   C . n 
C 1 34  GLY 34  -20 ?   ?   ?   C . n 
C 1 35  GLN 35  -19 ?   ?   ?   C . n 
C 1 36  ARG 36  -18 ?   ?   ?   C . n 
C 1 37  GLU 37  -17 ?   ?   ?   C . n 
C 1 38  PRO 38  -16 ?   ?   ?   C . n 
C 1 39  ASP 39  -15 ?   ?   ?   C . n 
C 1 40  TYR 40  -14 ?   ?   ?   C . n 
C 1 41  ASP 41  -13 ?   ?   ?   C . n 
C 1 42  ILE 42  -12 ?   ?   ?   C . n 
C 1 43  PRO 43  -11 ?   ?   ?   C . n 
C 1 44  THR 44  -10 ?   ?   ?   C . n 
C 1 45  THR 45  -9  ?   ?   ?   C . n 
C 1 46  GLU 46  -8  ?   ?   ?   C . n 
C 1 47  ASN 47  -7  ?   ?   ?   C . n 
C 1 48  LEU 48  -6  ?   ?   ?   C . n 
C 1 49  TYR 49  -5  ?   ?   ?   C . n 
C 1 50  PHE 50  -4  ?   ?   ?   C . n 
C 1 51  GLN 51  -3  ?   ?   ?   C . n 
C 1 52  GLY 52  -2  ?   ?   ?   C . n 
C 1 53  THR 53  -1  ?   ?   ?   C . n 
C 1 54  GLY 54  0   ?   ?   ?   C . n 
C 1 55  GLN 55  1   ?   ?   ?   C . n 
C 1 56  SER 56  2   ?   ?   ?   C . n 
C 1 57  VAL 57  3   ?   ?   ?   C . n 
C 1 58  ASN 58  4   4   ASN ASN C . n 
C 1 59  ASP 59  5   5   ASP ASP C . n 
C 1 60  PRO 60  6   6   PRO PRO C . n 
C 1 61  GLY 61  7   7   GLY GLY C . n 
C 1 62  ASN 62  8   8   ASN ASN C . n 
C 1 63  MET 63  9   9   MET MET C . n 
C 1 64  SER 64  10  10  SER SER C . n 
C 1 65  PHE 65  11  11  PHE PHE C . n 
C 1 66  VAL 66  12  12  VAL VAL C . n 
C 1 67  LYS 67  13  13  LYS LYS C . n 
C 1 68  GLU 68  14  14  GLU GLU C . n 
C 1 69  THR 69  15  15  THR THR C . n 
C 1 70  VAL 70  16  16  VAL VAL C . n 
C 1 71  ASP 71  17  17  ASP ASP C . n 
C 1 72  LYS 72  18  18  LYS LYS C . n 
C 1 73  LEU 73  19  19  LEU LEU C . n 
C 1 74  LEU 74  20  20  LEU LEU C . n 
C 1 75  LYS 75  21  21  LYS LYS C . n 
C 1 76  GLY 76  22  22  GLY GLY C . n 
C 1 77  TYR 77  23  23  TYR TYR C . n 
C 1 78  ASP 78  24  24  ASP ASP C . n 
C 1 79  ILE 79  25  25  ILE ILE C . n 
C 1 80  ARG 80  26  26  ARG ARG C . n 
C 1 81  LEU 81  27  27  LEU LEU C . n 
C 1 82  ARG 82  28  28  ARG ARG C . n 
C 1 83  PRO 83  29  29  PRO PRO C . n 
C 1 84  ASP 84  30  30  ASP ASP C . n 
C 1 85  PHE 85  31  31  PHE PHE C . n 
C 1 86  GLY 86  32  32  GLY GLY C . n 
C 1 87  GLY 87  33  33  GLY GLY C . n 
C 1 88  PRO 88  34  34  PRO PRO C . n 
C 1 89  PRO 89  35  35  PRO PRO C . n 
C 1 90  VAL 90  36  36  VAL VAL C . n 
C 1 91  CYS 91  37  37  CYS CYS C . n 
C 1 92  VAL 92  38  38  VAL VAL C . n 
C 1 93  GLY 93  39  39  GLY GLY C . n 
C 1 94  MET 94  40  40  MET MET C . n 
C 1 95  ASN 95  41  41  ASN ASN C . n 
C 1 96  ILE 96  42  42  ILE ILE C . n 
C 1 97  ASP 97  43  43  ASP ASP C . n 
C 1 98  ILE 98  44  44  ILE ILE C . n 
C 1 99  ALA 99  45  45  ALA ALA C . n 
C 1 100 SER 100 46  46  SER SER C . n 
C 1 101 ILE 101 47  47  ILE ILE C . n 
C 1 102 ASP 102 48  48  ASP ASP C . n 
C 1 103 MET 103 49  49  MET MET C . n 
C 1 104 VAL 104 50  50  VAL VAL C . n 
C 1 105 SER 105 51  51  SER SER C . n 
C 1 106 GLU 106 52  52  GLU GLU C . n 
C 1 107 VAL 107 53  53  VAL VAL C . n 
C 1 108 ASN 108 54  54  ASN ASN C . n 
C 1 109 MET 109 55  55  MET MET C . n 
C 1 110 ASP 110 56  56  ASP ASP C . n 
C 1 111 TYR 111 57  57  TYR TYR C . n 
C 1 112 THR 112 58  58  THR THR C . n 
C 1 113 LEU 113 59  59  LEU LEU C . n 
C 1 114 THR 114 60  60  THR THR C . n 
C 1 115 MET 115 61  61  MET MET C . n 
C 1 116 TYR 116 62  62  TYR TYR C . n 
C 1 117 PHE 117 63  63  PHE PHE C . n 
C 1 118 GLN 118 64  64  GLN GLN C . n 
C 1 119 GLN 119 65  65  GLN GLN C . n 
C 1 120 TYR 120 66  66  TYR TYR C . n 
C 1 121 TRP 121 67  67  TRP TRP C . n 
C 1 122 ARG 122 68  68  ARG ARG C . n 
C 1 123 ASP 123 69  69  ASP ASP C . n 
C 1 124 LYS 124 70  70  LYS LYS C . n 
C 1 125 ARG 125 71  71  ARG ARG C . n 
C 1 126 LEU 126 72  72  LEU LEU C . n 
C 1 127 ALA 127 73  73  ALA ALA C . n 
C 1 128 TYR 128 74  74  TYR TYR C . n 
C 1 129 SER 129 75  75  SER SER C . n 
C 1 130 GLY 130 76  76  GLY GLY C . n 
C 1 131 ILE 131 77  77  ILE ILE C . n 
C 1 132 PRO 132 78  78  PRO PRO C . n 
C 1 133 LEU 133 79  79  LEU LEU C . n 
C 1 134 ASN 134 80  80  ASN ASN C . n 
C 1 135 LEU 135 81  81  LEU LEU C . n 
C 1 136 THR 136 82  82  THR THR C . n 
C 1 137 LEU 137 83  83  LEU LEU C . n 
C 1 138 ASP 138 84  84  ASP ASP C . n 
C 1 139 ASN 139 85  85  ASN ASN C . n 
C 1 140 ARG 140 86  86  ARG ARG C . n 
C 1 141 VAL 141 87  87  VAL VAL C . n 
C 1 142 ALA 142 88  88  ALA ALA C . n 
C 1 143 ASP 143 89  89  ASP ASP C . n 
C 1 144 GLN 144 90  90  GLN GLN C . n 
C 1 145 LEU 145 91  91  LEU LEU C . n 
C 1 146 TRP 146 92  92  TRP TRP C . n 
C 1 147 VAL 147 93  93  VAL VAL C . n 
C 1 148 PRO 148 94  94  PRO PRO C . n 
C 1 149 ASP 149 95  95  ASP ASP C . n 
C 1 150 THR 150 96  96  THR THR C . n 
C 1 151 TYR 151 97  97  TYR TYR C . n 
C 1 152 PHE 152 98  98  PHE PHE C . n 
C 1 153 LEU 153 99  99  LEU LEU C . n 
C 1 154 ASN 154 100 100 ASN ASN C . n 
C 1 155 ASP 155 101 101 ASP ASP C . n 
C 1 156 LYS 156 102 102 LYS LYS C . n 
C 1 157 LYS 157 103 103 LYS LYS C . n 
C 1 158 SER 158 104 104 SER SER C . n 
C 1 159 PHE 159 105 105 PHE PHE C . n 
C 1 160 VAL 160 106 106 VAL VAL C . n 
C 1 161 HIS 161 107 107 HIS HIS C . n 
C 1 162 GLY 162 108 108 GLY GLY C . n 
C 1 163 VAL 163 109 109 VAL VAL C . n 
C 1 164 THR 164 110 110 THR THR C . n 
C 1 165 VAL 165 111 111 VAL VAL C . n 
C 1 166 LYS 166 112 112 LYS LYS C . n 
C 1 167 ASN 167 113 113 ASN ASN C . n 
C 1 168 ARG 168 114 114 ARG ARG C . n 
C 1 169 MET 169 115 115 MET MET C . n 
C 1 170 ILE 170 116 116 ILE ILE C . n 
C 1 171 ARG 171 117 117 ARG ARG C . n 
C 1 172 LEU 172 118 118 LEU LEU C . n 
C 1 173 HIS 173 119 119 HIS HIS C . n 
C 1 174 PRO 174 120 120 PRO PRO C . n 
C 1 175 ASP 175 121 121 ASP ASP C . n 
C 1 176 GLY 176 122 122 GLY GLY C . n 
C 1 177 THR 177 123 123 THR THR C . n 
C 1 178 VAL 178 124 124 VAL VAL C . n 
C 1 179 LEU 179 125 125 LEU LEU C . n 
C 1 180 TYR 180 126 126 TYR TYR C . n 
C 1 181 GLY 181 127 127 GLY GLY C . n 
C 1 182 LEU 182 128 128 LEU LEU C . n 
C 1 183 ARG 183 129 129 ARG ARG C . n 
C 1 184 ILE 184 130 130 ILE ILE C . n 
C 1 185 THR 185 131 131 THR THR C . n 
C 1 186 THR 186 132 132 THR THR C . n 
C 1 187 THR 187 133 133 THR THR C . n 
C 1 188 ALA 188 134 134 ALA ALA C . n 
C 1 189 ALA 189 135 135 ALA ALA C . n 
C 1 190 CYS 190 136 136 CYS CYS C . n 
C 1 191 MET 191 137 137 MET MET C . n 
C 1 192 MET 192 138 138 MET MET C . n 
C 1 193 ASP 193 139 139 ASP ASP C . n 
C 1 194 LEU 194 140 140 LEU LEU C . n 
C 1 195 ARG 195 141 141 ARG ARG C . n 
C 1 196 ARG 196 142 142 ARG ARG C . n 
C 1 197 TYR 197 143 143 TYR TYR C . n 
C 1 198 PRO 198 144 144 PRO PRO C . n 
C 1 199 LEU 199 145 145 LEU LEU C . n 
C 1 200 ASP 200 146 146 ASP ASP C . n 
C 1 201 GLU 201 147 147 GLU GLU C . n 
C 1 202 GLN 202 148 148 GLN GLN C . n 
C 1 203 ASN 203 149 149 ASN ASN C . n 
C 1 204 CYS 204 150 150 CYS CYS C . n 
C 1 205 THR 205 151 151 THR THR C . n 
C 1 206 LEU 206 152 152 LEU LEU C . n 
C 1 207 GLU 207 153 153 GLU GLU C . n 
C 1 208 ILE 208 154 154 ILE ILE C . n 
C 1 209 GLU 209 155 155 GLU GLU C . n 
C 1 210 SER 210 156 156 SER SER C . n 
C 1 211 TYR 211 157 157 TYR TYR C . n 
C 1 212 GLY 212 158 158 GLY GLY C . n 
C 1 213 TYR 213 159 159 TYR TYR C . n 
C 1 214 THR 214 160 160 THR THR C . n 
C 1 215 THR 215 161 161 THR THR C . n 
C 1 216 ASP 216 162 162 ASP ASP C . n 
C 1 217 ASP 217 163 163 ASP ASP C . n 
C 1 218 ILE 218 164 164 ILE ILE C . n 
C 1 219 GLU 219 165 165 GLU GLU C . n 
C 1 220 PHE 220 166 166 PHE PHE C . n 
C 1 221 TYR 221 167 167 TYR TYR C . n 
C 1 222 TRP 222 168 168 TRP TRP C . n 
C 1 223 ARG 223 169 169 ARG ARG C . n 
C 1 224 GLY 224 170 170 GLY GLY C . n 
C 1 225 GLY 225 171 171 GLY GLY C . n 
C 1 226 ASP 226 172 172 ASP ASP C . n 
C 1 227 LYS 227 173 173 LYS LYS C . n 
C 1 228 ALA 228 174 174 ALA ALA C . n 
C 1 229 VAL 229 175 175 VAL VAL C . n 
C 1 230 THR 230 176 176 THR THR C . n 
C 1 231 GLY 231 177 177 GLY GLY C . n 
C 1 232 VAL 232 178 178 VAL VAL C . n 
C 1 233 GLU 233 179 179 GLU GLU C . n 
C 1 234 ARG 234 180 180 ARG ARG C . n 
C 1 235 ILE 235 181 181 ILE ILE C . n 
C 1 236 GLU 236 182 182 GLU GLU C . n 
C 1 237 LEU 237 183 183 LEU LEU C . n 
C 1 238 PRO 238 184 184 PRO PRO C . n 
C 1 239 GLN 239 185 185 GLN GLN C . n 
C 1 240 PHE 240 186 186 PHE PHE C . n 
C 1 241 SER 241 187 187 SER SER C . n 
C 1 242 ILE 242 188 188 ILE ILE C . n 
C 1 243 VAL 243 189 189 VAL VAL C . n 
C 1 244 GLU 244 190 190 GLU GLU C . n 
C 1 245 HIS 245 191 191 HIS HIS C . n 
C 1 246 ARG 246 192 192 ARG ARG C . n 
C 1 247 LEU 247 193 193 LEU LEU C . n 
C 1 248 VAL 248 194 194 VAL VAL C . n 
C 1 249 SER 249 195 195 SER SER C . n 
C 1 250 ARG 250 196 196 ARG ARG C . n 
C 1 251 ASN 251 197 197 ASN ASN C . n 
C 1 252 VAL 252 198 198 VAL VAL C . n 
C 1 253 VAL 253 199 199 VAL VAL C . n 
C 1 254 PHE 254 200 200 PHE PHE C . n 
C 1 255 ALA 255 201 201 ALA ALA C . n 
C 1 256 THR 256 202 202 THR THR C . n 
C 1 257 GLY 257 203 203 GLY GLY C . n 
C 1 258 ALA 258 204 204 ALA ALA C . n 
C 1 259 TYR 259 205 205 TYR TYR C . n 
C 1 260 PRO 260 206 206 PRO PRO C . n 
C 1 261 ARG 261 207 207 ARG ARG C . n 
C 1 262 LEU 262 208 208 LEU LEU C . n 
C 1 263 SER 263 209 209 SER SER C . n 
C 1 264 LEU 264 210 210 LEU LEU C . n 
C 1 265 SER 265 211 211 SER SER C . n 
C 1 266 PHE 266 212 212 PHE PHE C . n 
C 1 267 ARG 267 213 213 ARG ARG C . n 
C 1 268 LEU 268 214 214 LEU LEU C . n 
C 1 269 LYS 269 215 215 LYS LYS C . n 
C 1 270 ARG 270 216 216 ARG ARG C . n 
C 1 271 ASN 271 217 217 ASN ASN C . n 
C 1 272 ILE 272 218 218 ILE ILE C . n 
C 1 273 GLY 273 219 219 GLY GLY C . n 
C 1 274 TYR 274 220 220 TYR TYR C . n 
C 1 275 PHE 275 221 221 PHE PHE C . n 
C 1 276 ILE 276 222 222 ILE ILE C . n 
C 1 277 LEU 277 223 223 LEU LEU C . n 
C 1 278 GLN 278 224 224 GLN GLN C . n 
C 1 279 THR 279 225 225 THR THR C . n 
C 1 280 TYR 280 226 226 TYR TYR C . n 
C 1 281 MET 281 227 227 MET MET C . n 
C 1 282 PRO 282 228 228 PRO PRO C . n 
C 1 283 SER 283 229 229 SER SER C . n 
C 1 284 ILE 284 230 230 ILE ILE C . n 
C 1 285 LEU 285 231 231 LEU LEU C . n 
C 1 286 ILE 286 232 232 ILE ILE C . n 
C 1 287 THR 287 233 233 THR THR C . n 
C 1 288 ILE 288 234 234 ILE ILE C . n 
C 1 289 LEU 289 235 235 LEU LEU C . n 
C 1 290 SER 290 236 236 SER SER C . n 
C 1 291 TRP 291 237 237 TRP TRP C . n 
C 1 292 VAL 292 238 238 VAL VAL C . n 
C 1 293 SER 293 239 239 SER SER C . n 
C 1 294 PHE 294 240 240 PHE PHE C . n 
C 1 295 TRP 295 241 241 TRP TRP C . n 
C 1 296 ILE 296 242 242 ILE ILE C . n 
C 1 297 ASN 297 243 243 ASN ASN C . n 
C 1 298 TYR 298 244 244 TYR TYR C . n 
C 1 299 ASP 299 245 245 ASP ASP C . n 
C 1 300 ALA 300 246 246 ALA ALA C . n 
C 1 301 SER 301 247 247 SER SER C . n 
C 1 302 ALA 302 248 248 ALA ALA C . n 
C 1 303 ALA 303 249 249 ALA ALA C . n 
C 1 304 ARG 304 250 250 ARG ARG C . n 
C 1 305 VAL 305 251 251 VAL VAL C . n 
C 1 306 ALA 306 252 252 ALA ALA C . n 
C 1 307 LEU 307 253 253 LEU LEU C . n 
C 1 308 GLY 308 254 254 GLY GLY C . n 
C 1 309 ILE 309 255 255 ILE ILE C . n 
C 1 310 THR 310 256 256 THR THR C . n 
C 1 311 THR 311 257 257 THR THR C . n 
C 1 312 VAL 312 258 258 VAL VAL C . n 
C 1 313 LEU 313 259 259 LEU LEU C . n 
C 1 314 THR 314 260 260 THR THR C . n 
C 1 315 MET 315 261 261 MET MET C . n 
C 1 316 THR 316 262 262 THR THR C . n 
C 1 317 THR 317 263 263 THR THR C . n 
C 1 318 ILE 318 264 264 ILE ILE C . n 
C 1 319 ASN 319 265 265 ASN ASN C . n 
C 1 320 THR 320 266 266 THR THR C . n 
C 1 321 HIS 321 267 267 HIS HIS C . n 
C 1 322 LEU 322 268 268 LEU LEU C . n 
C 1 323 ARG 323 269 269 ARG ARG C . n 
C 1 324 GLU 324 270 270 GLU GLU C . n 
C 1 325 THR 325 271 271 THR THR C . n 
C 1 326 LEU 326 272 272 LEU LEU C . n 
C 1 327 PRO 327 273 273 PRO PRO C . n 
C 1 328 LYS 328 274 274 LYS LYS C . n 
C 1 329 ILE 329 275 275 ILE ILE C . n 
C 1 330 PRO 330 276 276 PRO PRO C . n 
C 1 331 TYR 331 277 277 TYR TYR C . n 
C 1 332 VAL 332 278 278 VAL VAL C . n 
C 1 333 LYS 333 279 279 LYS LYS C . n 
C 1 334 ALA 334 280 280 ALA ALA C . n 
C 1 335 ILE 335 281 281 ILE ILE C . n 
C 1 336 ASP 336 282 282 ASP ASP C . n 
C 1 337 MET 337 283 283 MET MET C . n 
C 1 338 TYR 338 284 284 TYR TYR C . n 
C 1 339 LEU 339 285 285 LEU LEU C . n 
C 1 340 MET 340 286 286 MET MET C . n 
C 1 341 GLY 341 287 287 GLY GLY C . n 
C 1 342 CYS 342 288 288 CYS CYS C . n 
C 1 343 PHE 343 289 289 PHE PHE C . n 
C 1 344 VAL 344 290 290 VAL VAL C . n 
C 1 345 PHE 345 291 291 PHE PHE C . n 
C 1 346 VAL 346 292 292 VAL VAL C . n 
C 1 347 PHE 347 293 293 PHE PHE C . n 
C 1 348 LEU 348 294 294 LEU LEU C . n 
C 1 349 ALA 349 295 295 ALA ALA C . n 
C 1 350 LEU 350 296 296 LEU LEU C . n 
C 1 351 LEU 351 297 297 LEU LEU C . n 
C 1 352 GLU 352 298 298 GLU GLU C . n 
C 1 353 TYR 353 299 299 TYR TYR C . n 
C 1 354 ALA 354 300 300 ALA ALA C . n 
C 1 355 PHE 355 301 301 PHE PHE C . n 
C 1 356 VAL 356 302 302 VAL VAL C . n 
C 1 357 ASN 357 303 303 ASN ASN C . n 
C 1 358 TYR 358 304 304 TYR TYR C . n 
C 1 359 ILE 359 305 305 ILE ILE C . n 
C 1 360 PHE 360 306 306 PHE PHE C . n 
C 1 361 PHE 361 307 307 PHE PHE C . n 
C 1 362 SER 362 308 308 SER SER C . n 
C 1 363 GLN 363 309 309 GLN GLN C . n 
C 1 364 PRO 364 310 310 PRO PRO C . n 
C 1 365 ALA 365 311 311 ALA ALA C . n 
C 1 366 ARG 366 312 312 ARG ARG C . n 
C 1 367 ALA 367 313 313 ALA ALA C . n 
C 1 368 ALA 368 314 314 ALA ALA C . n 
C 1 369 ALA 369 422 422 ALA ALA C . n 
C 1 370 ILE 370 423 423 ILE ILE C . n 
C 1 371 ASP 371 424 424 ASP ASP C . n 
C 1 372 ARG 372 425 425 ARG ARG C . n 
C 1 373 TRP 373 426 426 TRP TRP C . n 
C 1 374 SER 374 427 427 SER SER C . n 
C 1 375 ARG 375 428 428 ARG ARG C . n 
C 1 376 ILE 376 429 429 ILE ILE C . n 
C 1 377 VAL 377 430 430 VAL VAL C . n 
C 1 378 PHE 378 431 431 PHE PHE C . n 
C 1 379 PRO 379 432 432 PRO PRO C . n 
C 1 380 PHE 380 433 433 PHE PHE C . n 
C 1 381 THR 381 434 434 THR THR C . n 
C 1 382 PHE 382 435 435 PHE PHE C . n 
C 1 383 SER 383 436 436 SER SER C . n 
C 1 384 LEU 384 437 437 LEU LEU C . n 
C 1 385 PHE 385 438 438 PHE PHE C . n 
C 1 386 ASN 386 439 439 ASN ASN C . n 
C 1 387 LEU 387 440 440 LEU LEU C . n 
C 1 388 VAL 388 441 441 VAL VAL C . n 
C 1 389 TYR 389 442 442 TYR TYR C . n 
C 1 390 TRP 390 443 443 TRP TRP C . n 
C 1 391 LEU 391 444 444 LEU LEU C . n 
C 1 392 TYR 392 445 445 TYR TYR C . n 
C 1 393 TYR 393 446 446 TYR TYR C . n 
C 1 394 VAL 394 447 447 VAL VAL C . n 
C 1 395 ASN 395 448 ?   ?   ?   C . n 
D 1 1   MET 1   -53 ?   ?   ?   D . n 
D 1 2   ASP 2   -52 ?   ?   ?   D . n 
D 1 3   GLU 3   -51 ?   ?   ?   D . n 
D 1 4   LYS 4   -50 ?   ?   ?   D . n 
D 1 5   THR 5   -49 ?   ?   ?   D . n 
D 1 6   THR 6   -48 ?   ?   ?   D . n 
D 1 7   GLY 7   -47 ?   ?   ?   D . n 
D 1 8   TRP 8   -46 ?   ?   ?   D . n 
D 1 9   ARG 9   -45 ?   ?   ?   D . n 
D 1 10  GLY 10  -44 ?   ?   ?   D . n 
D 1 11  GLY 11  -43 ?   ?   ?   D . n 
D 1 12  HIS 12  -42 ?   ?   ?   D . n 
D 1 13  VAL 13  -41 ?   ?   ?   D . n 
D 1 14  VAL 14  -40 ?   ?   ?   D . n 
D 1 15  GLU 15  -39 ?   ?   ?   D . n 
D 1 16  GLY 16  -38 ?   ?   ?   D . n 
D 1 17  LEU 17  -37 ?   ?   ?   D . n 
D 1 18  ALA 18  -36 ?   ?   ?   D . n 
D 1 19  GLY 19  -35 ?   ?   ?   D . n 
D 1 20  GLU 20  -34 ?   ?   ?   D . n 
D 1 21  LEU 21  -33 ?   ?   ?   D . n 
D 1 22  GLU 22  -32 ?   ?   ?   D . n 
D 1 23  GLN 23  -31 ?   ?   ?   D . n 
D 1 24  LEU 24  -30 ?   ?   ?   D . n 
D 1 25  ARG 25  -29 ?   ?   ?   D . n 
D 1 26  ALA 26  -28 ?   ?   ?   D . n 
D 1 27  ARG 27  -27 ?   ?   ?   D . n 
D 1 28  LEU 28  -26 ?   ?   ?   D . n 
D 1 29  GLU 29  -25 ?   ?   ?   D . n 
D 1 30  HIS 30  -24 ?   ?   ?   D . n 
D 1 31  HIS 31  -23 ?   ?   ?   D . n 
D 1 32  PRO 32  -22 ?   ?   ?   D . n 
D 1 33  GLN 33  -21 ?   ?   ?   D . n 
D 1 34  GLY 34  -20 ?   ?   ?   D . n 
D 1 35  GLN 35  -19 ?   ?   ?   D . n 
D 1 36  ARG 36  -18 ?   ?   ?   D . n 
D 1 37  GLU 37  -17 ?   ?   ?   D . n 
D 1 38  PRO 38  -16 ?   ?   ?   D . n 
D 1 39  ASP 39  -15 ?   ?   ?   D . n 
D 1 40  TYR 40  -14 ?   ?   ?   D . n 
D 1 41  ASP 41  -13 ?   ?   ?   D . n 
D 1 42  ILE 42  -12 ?   ?   ?   D . n 
D 1 43  PRO 43  -11 ?   ?   ?   D . n 
D 1 44  THR 44  -10 ?   ?   ?   D . n 
D 1 45  THR 45  -9  ?   ?   ?   D . n 
D 1 46  GLU 46  -8  ?   ?   ?   D . n 
D 1 47  ASN 47  -7  ?   ?   ?   D . n 
D 1 48  LEU 48  -6  ?   ?   ?   D . n 
D 1 49  TYR 49  -5  ?   ?   ?   D . n 
D 1 50  PHE 50  -4  ?   ?   ?   D . n 
D 1 51  GLN 51  -3  ?   ?   ?   D . n 
D 1 52  GLY 52  -2  ?   ?   ?   D . n 
D 1 53  THR 53  -1  ?   ?   ?   D . n 
D 1 54  GLY 54  0   ?   ?   ?   D . n 
D 1 55  GLN 55  1   ?   ?   ?   D . n 
D 1 56  SER 56  2   ?   ?   ?   D . n 
D 1 57  VAL 57  3   ?   ?   ?   D . n 
D 1 58  ASN 58  4   4   ASN ASN D . n 
D 1 59  ASP 59  5   5   ASP ASP D . n 
D 1 60  PRO 60  6   6   PRO PRO D . n 
D 1 61  GLY 61  7   7   GLY GLY D . n 
D 1 62  ASN 62  8   8   ASN ASN D . n 
D 1 63  MET 63  9   9   MET MET D . n 
D 1 64  SER 64  10  10  SER SER D . n 
D 1 65  PHE 65  11  11  PHE PHE D . n 
D 1 66  VAL 66  12  12  VAL VAL D . n 
D 1 67  LYS 67  13  13  LYS LYS D . n 
D 1 68  GLU 68  14  14  GLU GLU D . n 
D 1 69  THR 69  15  15  THR THR D . n 
D 1 70  VAL 70  16  16  VAL VAL D . n 
D 1 71  ASP 71  17  17  ASP ASP D . n 
D 1 72  LYS 72  18  18  LYS LYS D . n 
D 1 73  LEU 73  19  19  LEU LEU D . n 
D 1 74  LEU 74  20  20  LEU LEU D . n 
D 1 75  LYS 75  21  21  LYS LYS D . n 
D 1 76  GLY 76  22  22  GLY GLY D . n 
D 1 77  TYR 77  23  23  TYR TYR D . n 
D 1 78  ASP 78  24  24  ASP ASP D . n 
D 1 79  ILE 79  25  25  ILE ILE D . n 
D 1 80  ARG 80  26  26  ARG ARG D . n 
D 1 81  LEU 81  27  27  LEU LEU D . n 
D 1 82  ARG 82  28  28  ARG ARG D . n 
D 1 83  PRO 83  29  29  PRO PRO D . n 
D 1 84  ASP 84  30  30  ASP ASP D . n 
D 1 85  PHE 85  31  31  PHE PHE D . n 
D 1 86  GLY 86  32  32  GLY GLY D . n 
D 1 87  GLY 87  33  33  GLY GLY D . n 
D 1 88  PRO 88  34  34  PRO PRO D . n 
D 1 89  PRO 89  35  35  PRO PRO D . n 
D 1 90  VAL 90  36  36  VAL VAL D . n 
D 1 91  CYS 91  37  37  CYS CYS D . n 
D 1 92  VAL 92  38  38  VAL VAL D . n 
D 1 93  GLY 93  39  39  GLY GLY D . n 
D 1 94  MET 94  40  40  MET MET D . n 
D 1 95  ASN 95  41  41  ASN ASN D . n 
D 1 96  ILE 96  42  42  ILE ILE D . n 
D 1 97  ASP 97  43  43  ASP ASP D . n 
D 1 98  ILE 98  44  44  ILE ILE D . n 
D 1 99  ALA 99  45  45  ALA ALA D . n 
D 1 100 SER 100 46  46  SER SER D . n 
D 1 101 ILE 101 47  47  ILE ILE D . n 
D 1 102 ASP 102 48  48  ASP ASP D . n 
D 1 103 MET 103 49  49  MET MET D . n 
D 1 104 VAL 104 50  50  VAL VAL D . n 
D 1 105 SER 105 51  51  SER SER D . n 
D 1 106 GLU 106 52  52  GLU GLU D . n 
D 1 107 VAL 107 53  53  VAL VAL D . n 
D 1 108 ASN 108 54  54  ASN ASN D . n 
D 1 109 MET 109 55  55  MET MET D . n 
D 1 110 ASP 110 56  56  ASP ASP D . n 
D 1 111 TYR 111 57  57  TYR TYR D . n 
D 1 112 THR 112 58  58  THR THR D . n 
D 1 113 LEU 113 59  59  LEU LEU D . n 
D 1 114 THR 114 60  60  THR THR D . n 
D 1 115 MET 115 61  61  MET MET D . n 
D 1 116 TYR 116 62  62  TYR TYR D . n 
D 1 117 PHE 117 63  63  PHE PHE D . n 
D 1 118 GLN 118 64  64  GLN GLN D . n 
D 1 119 GLN 119 65  65  GLN GLN D . n 
D 1 120 TYR 120 66  66  TYR TYR D . n 
D 1 121 TRP 121 67  67  TRP TRP D . n 
D 1 122 ARG 122 68  68  ARG ARG D . n 
D 1 123 ASP 123 69  69  ASP ASP D . n 
D 1 124 LYS 124 70  70  LYS LYS D . n 
D 1 125 ARG 125 71  71  ARG ARG D . n 
D 1 126 LEU 126 72  72  LEU LEU D . n 
D 1 127 ALA 127 73  73  ALA ALA D . n 
D 1 128 TYR 128 74  74  TYR TYR D . n 
D 1 129 SER 129 75  75  SER SER D . n 
D 1 130 GLY 130 76  76  GLY GLY D . n 
D 1 131 ILE 131 77  77  ILE ILE D . n 
D 1 132 PRO 132 78  78  PRO PRO D . n 
D 1 133 LEU 133 79  79  LEU LEU D . n 
D 1 134 ASN 134 80  80  ASN ASN D . n 
D 1 135 LEU 135 81  81  LEU LEU D . n 
D 1 136 THR 136 82  82  THR THR D . n 
D 1 137 LEU 137 83  83  LEU LEU D . n 
D 1 138 ASP 138 84  84  ASP ASP D . n 
D 1 139 ASN 139 85  85  ASN ASN D . n 
D 1 140 ARG 140 86  86  ARG ARG D . n 
D 1 141 VAL 141 87  87  VAL VAL D . n 
D 1 142 ALA 142 88  88  ALA ALA D . n 
D 1 143 ASP 143 89  89  ASP ASP D . n 
D 1 144 GLN 144 90  90  GLN GLN D . n 
D 1 145 LEU 145 91  91  LEU LEU D . n 
D 1 146 TRP 146 92  92  TRP TRP D . n 
D 1 147 VAL 147 93  93  VAL VAL D . n 
D 1 148 PRO 148 94  94  PRO PRO D . n 
D 1 149 ASP 149 95  95  ASP ASP D . n 
D 1 150 THR 150 96  96  THR THR D . n 
D 1 151 TYR 151 97  97  TYR TYR D . n 
D 1 152 PHE 152 98  98  PHE PHE D . n 
D 1 153 LEU 153 99  99  LEU LEU D . n 
D 1 154 ASN 154 100 100 ASN ASN D . n 
D 1 155 ASP 155 101 101 ASP ASP D . n 
D 1 156 LYS 156 102 102 LYS LYS D . n 
D 1 157 LYS 157 103 103 LYS LYS D . n 
D 1 158 SER 158 104 104 SER SER D . n 
D 1 159 PHE 159 105 105 PHE PHE D . n 
D 1 160 VAL 160 106 106 VAL VAL D . n 
D 1 161 HIS 161 107 107 HIS HIS D . n 
D 1 162 GLY 162 108 108 GLY GLY D . n 
D 1 163 VAL 163 109 109 VAL VAL D . n 
D 1 164 THR 164 110 110 THR THR D . n 
D 1 165 VAL 165 111 111 VAL VAL D . n 
D 1 166 LYS 166 112 112 LYS LYS D . n 
D 1 167 ASN 167 113 113 ASN ASN D . n 
D 1 168 ARG 168 114 114 ARG ARG D . n 
D 1 169 MET 169 115 115 MET MET D . n 
D 1 170 ILE 170 116 116 ILE ILE D . n 
D 1 171 ARG 171 117 117 ARG ARG D . n 
D 1 172 LEU 172 118 118 LEU LEU D . n 
D 1 173 HIS 173 119 119 HIS HIS D . n 
D 1 174 PRO 174 120 120 PRO PRO D . n 
D 1 175 ASP 175 121 121 ASP ASP D . n 
D 1 176 GLY 176 122 122 GLY GLY D . n 
D 1 177 THR 177 123 123 THR THR D . n 
D 1 178 VAL 178 124 124 VAL VAL D . n 
D 1 179 LEU 179 125 125 LEU LEU D . n 
D 1 180 TYR 180 126 126 TYR TYR D . n 
D 1 181 GLY 181 127 127 GLY GLY D . n 
D 1 182 LEU 182 128 128 LEU LEU D . n 
D 1 183 ARG 183 129 129 ARG ARG D . n 
D 1 184 ILE 184 130 130 ILE ILE D . n 
D 1 185 THR 185 131 131 THR THR D . n 
D 1 186 THR 186 132 132 THR THR D . n 
D 1 187 THR 187 133 133 THR THR D . n 
D 1 188 ALA 188 134 134 ALA ALA D . n 
D 1 189 ALA 189 135 135 ALA ALA D . n 
D 1 190 CYS 190 136 136 CYS CYS D . n 
D 1 191 MET 191 137 137 MET MET D . n 
D 1 192 MET 192 138 138 MET MET D . n 
D 1 193 ASP 193 139 139 ASP ASP D . n 
D 1 194 LEU 194 140 140 LEU LEU D . n 
D 1 195 ARG 195 141 141 ARG ARG D . n 
D 1 196 ARG 196 142 142 ARG ARG D . n 
D 1 197 TYR 197 143 143 TYR TYR D . n 
D 1 198 PRO 198 144 144 PRO PRO D . n 
D 1 199 LEU 199 145 145 LEU LEU D . n 
D 1 200 ASP 200 146 146 ASP ASP D . n 
D 1 201 GLU 201 147 147 GLU GLU D . n 
D 1 202 GLN 202 148 148 GLN GLN D . n 
D 1 203 ASN 203 149 149 ASN ASN D . n 
D 1 204 CYS 204 150 150 CYS CYS D . n 
D 1 205 THR 205 151 151 THR THR D . n 
D 1 206 LEU 206 152 152 LEU LEU D . n 
D 1 207 GLU 207 153 153 GLU GLU D . n 
D 1 208 ILE 208 154 154 ILE ILE D . n 
D 1 209 GLU 209 155 155 GLU GLU D . n 
D 1 210 SER 210 156 156 SER SER D . n 
D 1 211 TYR 211 157 157 TYR TYR D . n 
D 1 212 GLY 212 158 158 GLY GLY D . n 
D 1 213 TYR 213 159 159 TYR TYR D . n 
D 1 214 THR 214 160 160 THR THR D . n 
D 1 215 THR 215 161 161 THR THR D . n 
D 1 216 ASP 216 162 162 ASP ASP D . n 
D 1 217 ASP 217 163 163 ASP ASP D . n 
D 1 218 ILE 218 164 164 ILE ILE D . n 
D 1 219 GLU 219 165 165 GLU GLU D . n 
D 1 220 PHE 220 166 166 PHE PHE D . n 
D 1 221 TYR 221 167 167 TYR TYR D . n 
D 1 222 TRP 222 168 168 TRP TRP D . n 
D 1 223 ARG 223 169 169 ARG ARG D . n 
D 1 224 GLY 224 170 170 GLY GLY D . n 
D 1 225 GLY 225 171 171 GLY GLY D . n 
D 1 226 ASP 226 172 172 ASP ASP D . n 
D 1 227 LYS 227 173 173 LYS LYS D . n 
D 1 228 ALA 228 174 174 ALA ALA D . n 
D 1 229 VAL 229 175 175 VAL VAL D . n 
D 1 230 THR 230 176 176 THR THR D . n 
D 1 231 GLY 231 177 177 GLY GLY D . n 
D 1 232 VAL 232 178 178 VAL VAL D . n 
D 1 233 GLU 233 179 179 GLU GLU D . n 
D 1 234 ARG 234 180 180 ARG ARG D . n 
D 1 235 ILE 235 181 181 ILE ILE D . n 
D 1 236 GLU 236 182 182 GLU GLU D . n 
D 1 237 LEU 237 183 183 LEU LEU D . n 
D 1 238 PRO 238 184 184 PRO PRO D . n 
D 1 239 GLN 239 185 185 GLN GLN D . n 
D 1 240 PHE 240 186 186 PHE PHE D . n 
D 1 241 SER 241 187 187 SER SER D . n 
D 1 242 ILE 242 188 188 ILE ILE D . n 
D 1 243 VAL 243 189 189 VAL VAL D . n 
D 1 244 GLU 244 190 190 GLU GLU D . n 
D 1 245 HIS 245 191 191 HIS HIS D . n 
D 1 246 ARG 246 192 192 ARG ARG D . n 
D 1 247 LEU 247 193 193 LEU LEU D . n 
D 1 248 VAL 248 194 194 VAL VAL D . n 
D 1 249 SER 249 195 195 SER SER D . n 
D 1 250 ARG 250 196 196 ARG ARG D . n 
D 1 251 ASN 251 197 197 ASN ASN D . n 
D 1 252 VAL 252 198 198 VAL VAL D . n 
D 1 253 VAL 253 199 199 VAL VAL D . n 
D 1 254 PHE 254 200 200 PHE PHE D . n 
D 1 255 ALA 255 201 201 ALA ALA D . n 
D 1 256 THR 256 202 202 THR THR D . n 
D 1 257 GLY 257 203 203 GLY GLY D . n 
D 1 258 ALA 258 204 204 ALA ALA D . n 
D 1 259 TYR 259 205 205 TYR TYR D . n 
D 1 260 PRO 260 206 206 PRO PRO D . n 
D 1 261 ARG 261 207 207 ARG ARG D . n 
D 1 262 LEU 262 208 208 LEU LEU D . n 
D 1 263 SER 263 209 209 SER SER D . n 
D 1 264 LEU 264 210 210 LEU LEU D . n 
D 1 265 SER 265 211 211 SER SER D . n 
D 1 266 PHE 266 212 212 PHE PHE D . n 
D 1 267 ARG 267 213 213 ARG ARG D . n 
D 1 268 LEU 268 214 214 LEU LEU D . n 
D 1 269 LYS 269 215 215 LYS LYS D . n 
D 1 270 ARG 270 216 216 ARG ARG D . n 
D 1 271 ASN 271 217 217 ASN ASN D . n 
D 1 272 ILE 272 218 218 ILE ILE D . n 
D 1 273 GLY 273 219 219 GLY GLY D . n 
D 1 274 TYR 274 220 220 TYR TYR D . n 
D 1 275 PHE 275 221 221 PHE PHE D . n 
D 1 276 ILE 276 222 222 ILE ILE D . n 
D 1 277 LEU 277 223 223 LEU LEU D . n 
D 1 278 GLN 278 224 224 GLN GLN D . n 
D 1 279 THR 279 225 225 THR THR D . n 
D 1 280 TYR 280 226 226 TYR TYR D . n 
D 1 281 MET 281 227 227 MET MET D . n 
D 1 282 PRO 282 228 228 PRO PRO D . n 
D 1 283 SER 283 229 229 SER SER D . n 
D 1 284 ILE 284 230 230 ILE ILE D . n 
D 1 285 LEU 285 231 231 LEU LEU D . n 
D 1 286 ILE 286 232 232 ILE ILE D . n 
D 1 287 THR 287 233 233 THR THR D . n 
D 1 288 ILE 288 234 234 ILE ILE D . n 
D 1 289 LEU 289 235 235 LEU LEU D . n 
D 1 290 SER 290 236 236 SER SER D . n 
D 1 291 TRP 291 237 237 TRP TRP D . n 
D 1 292 VAL 292 238 238 VAL VAL D . n 
D 1 293 SER 293 239 239 SER SER D . n 
D 1 294 PHE 294 240 240 PHE PHE D . n 
D 1 295 TRP 295 241 241 TRP TRP D . n 
D 1 296 ILE 296 242 242 ILE ILE D . n 
D 1 297 ASN 297 243 243 ASN ASN D . n 
D 1 298 TYR 298 244 244 TYR TYR D . n 
D 1 299 ASP 299 245 245 ASP ASP D . n 
D 1 300 ALA 300 246 246 ALA ALA D . n 
D 1 301 SER 301 247 247 SER SER D . n 
D 1 302 ALA 302 248 248 ALA ALA D . n 
D 1 303 ALA 303 249 249 ALA ALA D . n 
D 1 304 ARG 304 250 250 ARG ARG D . n 
D 1 305 VAL 305 251 251 VAL VAL D . n 
D 1 306 ALA 306 252 252 ALA ALA D . n 
D 1 307 LEU 307 253 253 LEU LEU D . n 
D 1 308 GLY 308 254 254 GLY GLY D . n 
D 1 309 ILE 309 255 255 ILE ILE D . n 
D 1 310 THR 310 256 256 THR THR D . n 
D 1 311 THR 311 257 257 THR THR D . n 
D 1 312 VAL 312 258 258 VAL VAL D . n 
D 1 313 LEU 313 259 259 LEU LEU D . n 
D 1 314 THR 314 260 260 THR THR D . n 
D 1 315 MET 315 261 261 MET MET D . n 
D 1 316 THR 316 262 262 THR THR D . n 
D 1 317 THR 317 263 263 THR THR D . n 
D 1 318 ILE 318 264 264 ILE ILE D . n 
D 1 319 ASN 319 265 265 ASN ASN D . n 
D 1 320 THR 320 266 266 THR THR D . n 
D 1 321 HIS 321 267 267 HIS HIS D . n 
D 1 322 LEU 322 268 268 LEU LEU D . n 
D 1 323 ARG 323 269 269 ARG ARG D . n 
D 1 324 GLU 324 270 270 GLU GLU D . n 
D 1 325 THR 325 271 271 THR THR D . n 
D 1 326 LEU 326 272 272 LEU LEU D . n 
D 1 327 PRO 327 273 273 PRO PRO D . n 
D 1 328 LYS 328 274 274 LYS LYS D . n 
D 1 329 ILE 329 275 275 ILE ILE D . n 
D 1 330 PRO 330 276 276 PRO PRO D . n 
D 1 331 TYR 331 277 277 TYR TYR D . n 
D 1 332 VAL 332 278 278 VAL VAL D . n 
D 1 333 LYS 333 279 279 LYS LYS D . n 
D 1 334 ALA 334 280 280 ALA ALA D . n 
D 1 335 ILE 335 281 281 ILE ILE D . n 
D 1 336 ASP 336 282 282 ASP ASP D . n 
D 1 337 MET 337 283 283 MET MET D . n 
D 1 338 TYR 338 284 284 TYR TYR D . n 
D 1 339 LEU 339 285 285 LEU LEU D . n 
D 1 340 MET 340 286 286 MET MET D . n 
D 1 341 GLY 341 287 287 GLY GLY D . n 
D 1 342 CYS 342 288 288 CYS CYS D . n 
D 1 343 PHE 343 289 289 PHE PHE D . n 
D 1 344 VAL 344 290 290 VAL VAL D . n 
D 1 345 PHE 345 291 291 PHE PHE D . n 
D 1 346 VAL 346 292 292 VAL VAL D . n 
D 1 347 PHE 347 293 293 PHE PHE D . n 
D 1 348 LEU 348 294 294 LEU LEU D . n 
D 1 349 ALA 349 295 295 ALA ALA D . n 
D 1 350 LEU 350 296 296 LEU LEU D . n 
D 1 351 LEU 351 297 297 LEU LEU D . n 
D 1 352 GLU 352 298 298 GLU GLU D . n 
D 1 353 TYR 353 299 299 TYR TYR D . n 
D 1 354 ALA 354 300 300 ALA ALA D . n 
D 1 355 PHE 355 301 301 PHE PHE D . n 
D 1 356 VAL 356 302 302 VAL VAL D . n 
D 1 357 ASN 357 303 303 ASN ASN D . n 
D 1 358 TYR 358 304 304 TYR TYR D . n 
D 1 359 ILE 359 305 305 ILE ILE D . n 
D 1 360 PHE 360 306 306 PHE PHE D . n 
D 1 361 PHE 361 307 307 PHE PHE D . n 
D 1 362 SER 362 308 308 SER SER D . n 
D 1 363 GLN 363 309 309 GLN GLN D . n 
D 1 364 PRO 364 310 310 PRO PRO D . n 
D 1 365 ALA 365 311 311 ALA ALA D . n 
D 1 366 ARG 366 312 312 ARG ARG D . n 
D 1 367 ALA 367 313 313 ALA ALA D . n 
D 1 368 ALA 368 314 314 ALA ALA D . n 
D 1 369 ALA 369 422 422 ALA ALA D . n 
D 1 370 ILE 370 423 423 ILE ILE D . n 
D 1 371 ASP 371 424 424 ASP ASP D . n 
D 1 372 ARG 372 425 425 ARG ARG D . n 
D 1 373 TRP 373 426 426 TRP TRP D . n 
D 1 374 SER 374 427 427 SER SER D . n 
D 1 375 ARG 375 428 428 ARG ARG D . n 
D 1 376 ILE 376 429 429 ILE ILE D . n 
D 1 377 VAL 377 430 430 VAL VAL D . n 
D 1 378 PHE 378 431 431 PHE PHE D . n 
D 1 379 PRO 379 432 432 PRO PRO D . n 
D 1 380 PHE 380 433 433 PHE PHE D . n 
D 1 381 THR 381 434 434 THR THR D . n 
D 1 382 PHE 382 435 435 PHE PHE D . n 
D 1 383 SER 383 436 436 SER SER D . n 
D 1 384 LEU 384 437 437 LEU LEU D . n 
D 1 385 PHE 385 438 438 PHE PHE D . n 
D 1 386 ASN 386 439 439 ASN ASN D . n 
D 1 387 LEU 387 440 440 LEU LEU D . n 
D 1 388 VAL 388 441 441 VAL VAL D . n 
D 1 389 TYR 389 442 442 TYR TYR D . n 
D 1 390 TRP 390 443 443 TRP TRP D . n 
D 1 391 LEU 391 444 444 LEU LEU D . n 
D 1 392 TYR 392 445 445 TYR TYR D . n 
D 1 393 TYR 393 446 446 TYR TYR D . n 
D 1 394 VAL 394 447 447 VAL VAL D . n 
D 1 395 ASN 395 448 ?   ?   ?   D . n 
E 1 1   MET 1   -53 ?   ?   ?   E . n 
E 1 2   ASP 2   -52 ?   ?   ?   E . n 
E 1 3   GLU 3   -51 ?   ?   ?   E . n 
E 1 4   LYS 4   -50 ?   ?   ?   E . n 
E 1 5   THR 5   -49 ?   ?   ?   E . n 
E 1 6   THR 6   -48 ?   ?   ?   E . n 
E 1 7   GLY 7   -47 ?   ?   ?   E . n 
E 1 8   TRP 8   -46 ?   ?   ?   E . n 
E 1 9   ARG 9   -45 ?   ?   ?   E . n 
E 1 10  GLY 10  -44 ?   ?   ?   E . n 
E 1 11  GLY 11  -43 ?   ?   ?   E . n 
E 1 12  HIS 12  -42 ?   ?   ?   E . n 
E 1 13  VAL 13  -41 ?   ?   ?   E . n 
E 1 14  VAL 14  -40 ?   ?   ?   E . n 
E 1 15  GLU 15  -39 ?   ?   ?   E . n 
E 1 16  GLY 16  -38 ?   ?   ?   E . n 
E 1 17  LEU 17  -37 ?   ?   ?   E . n 
E 1 18  ALA 18  -36 ?   ?   ?   E . n 
E 1 19  GLY 19  -35 ?   ?   ?   E . n 
E 1 20  GLU 20  -34 ?   ?   ?   E . n 
E 1 21  LEU 21  -33 ?   ?   ?   E . n 
E 1 22  GLU 22  -32 ?   ?   ?   E . n 
E 1 23  GLN 23  -31 ?   ?   ?   E . n 
E 1 24  LEU 24  -30 ?   ?   ?   E . n 
E 1 25  ARG 25  -29 ?   ?   ?   E . n 
E 1 26  ALA 26  -28 ?   ?   ?   E . n 
E 1 27  ARG 27  -27 ?   ?   ?   E . n 
E 1 28  LEU 28  -26 ?   ?   ?   E . n 
E 1 29  GLU 29  -25 ?   ?   ?   E . n 
E 1 30  HIS 30  -24 ?   ?   ?   E . n 
E 1 31  HIS 31  -23 ?   ?   ?   E . n 
E 1 32  PRO 32  -22 ?   ?   ?   E . n 
E 1 33  GLN 33  -21 ?   ?   ?   E . n 
E 1 34  GLY 34  -20 ?   ?   ?   E . n 
E 1 35  GLN 35  -19 ?   ?   ?   E . n 
E 1 36  ARG 36  -18 ?   ?   ?   E . n 
E 1 37  GLU 37  -17 ?   ?   ?   E . n 
E 1 38  PRO 38  -16 ?   ?   ?   E . n 
E 1 39  ASP 39  -15 ?   ?   ?   E . n 
E 1 40  TYR 40  -14 ?   ?   ?   E . n 
E 1 41  ASP 41  -13 ?   ?   ?   E . n 
E 1 42  ILE 42  -12 ?   ?   ?   E . n 
E 1 43  PRO 43  -11 ?   ?   ?   E . n 
E 1 44  THR 44  -10 ?   ?   ?   E . n 
E 1 45  THR 45  -9  ?   ?   ?   E . n 
E 1 46  GLU 46  -8  ?   ?   ?   E . n 
E 1 47  ASN 47  -7  ?   ?   ?   E . n 
E 1 48  LEU 48  -6  ?   ?   ?   E . n 
E 1 49  TYR 49  -5  ?   ?   ?   E . n 
E 1 50  PHE 50  -4  ?   ?   ?   E . n 
E 1 51  GLN 51  -3  ?   ?   ?   E . n 
E 1 52  GLY 52  -2  ?   ?   ?   E . n 
E 1 53  THR 53  -1  ?   ?   ?   E . n 
E 1 54  GLY 54  0   ?   ?   ?   E . n 
E 1 55  GLN 55  1   ?   ?   ?   E . n 
E 1 56  SER 56  2   ?   ?   ?   E . n 
E 1 57  VAL 57  3   ?   ?   ?   E . n 
E 1 58  ASN 58  4   4   ASN ASN E . n 
E 1 59  ASP 59  5   5   ASP ASP E . n 
E 1 60  PRO 60  6   6   PRO PRO E . n 
E 1 61  GLY 61  7   7   GLY GLY E . n 
E 1 62  ASN 62  8   8   ASN ASN E . n 
E 1 63  MET 63  9   9   MET MET E . n 
E 1 64  SER 64  10  10  SER SER E . n 
E 1 65  PHE 65  11  11  PHE PHE E . n 
E 1 66  VAL 66  12  12  VAL VAL E . n 
E 1 67  LYS 67  13  13  LYS LYS E . n 
E 1 68  GLU 68  14  14  GLU GLU E . n 
E 1 69  THR 69  15  15  THR THR E . n 
E 1 70  VAL 70  16  16  VAL VAL E . n 
E 1 71  ASP 71  17  17  ASP ASP E . n 
E 1 72  LYS 72  18  18  LYS LYS E . n 
E 1 73  LEU 73  19  19  LEU LEU E . n 
E 1 74  LEU 74  20  20  LEU LEU E . n 
E 1 75  LYS 75  21  21  LYS LYS E . n 
E 1 76  GLY 76  22  22  GLY GLY E . n 
E 1 77  TYR 77  23  23  TYR TYR E . n 
E 1 78  ASP 78  24  24  ASP ASP E . n 
E 1 79  ILE 79  25  25  ILE ILE E . n 
E 1 80  ARG 80  26  26  ARG ARG E . n 
E 1 81  LEU 81  27  27  LEU LEU E . n 
E 1 82  ARG 82  28  28  ARG ARG E . n 
E 1 83  PRO 83  29  29  PRO PRO E . n 
E 1 84  ASP 84  30  30  ASP ASP E . n 
E 1 85  PHE 85  31  31  PHE PHE E . n 
E 1 86  GLY 86  32  32  GLY GLY E . n 
E 1 87  GLY 87  33  33  GLY GLY E . n 
E 1 88  PRO 88  34  34  PRO PRO E . n 
E 1 89  PRO 89  35  35  PRO PRO E . n 
E 1 90  VAL 90  36  36  VAL VAL E . n 
E 1 91  CYS 91  37  37  CYS CYS E . n 
E 1 92  VAL 92  38  38  VAL VAL E . n 
E 1 93  GLY 93  39  39  GLY GLY E . n 
E 1 94  MET 94  40  40  MET MET E . n 
E 1 95  ASN 95  41  41  ASN ASN E . n 
E 1 96  ILE 96  42  42  ILE ILE E . n 
E 1 97  ASP 97  43  43  ASP ASP E . n 
E 1 98  ILE 98  44  44  ILE ILE E . n 
E 1 99  ALA 99  45  45  ALA ALA E . n 
E 1 100 SER 100 46  46  SER SER E . n 
E 1 101 ILE 101 47  47  ILE ILE E . n 
E 1 102 ASP 102 48  48  ASP ASP E . n 
E 1 103 MET 103 49  49  MET MET E . n 
E 1 104 VAL 104 50  50  VAL VAL E . n 
E 1 105 SER 105 51  51  SER SER E . n 
E 1 106 GLU 106 52  52  GLU GLU E . n 
E 1 107 VAL 107 53  53  VAL VAL E . n 
E 1 108 ASN 108 54  54  ASN ASN E . n 
E 1 109 MET 109 55  55  MET MET E . n 
E 1 110 ASP 110 56  56  ASP ASP E . n 
E 1 111 TYR 111 57  57  TYR TYR E . n 
E 1 112 THR 112 58  58  THR THR E . n 
E 1 113 LEU 113 59  59  LEU LEU E . n 
E 1 114 THR 114 60  60  THR THR E . n 
E 1 115 MET 115 61  61  MET MET E . n 
E 1 116 TYR 116 62  62  TYR TYR E . n 
E 1 117 PHE 117 63  63  PHE PHE E . n 
E 1 118 GLN 118 64  64  GLN GLN E . n 
E 1 119 GLN 119 65  65  GLN GLN E . n 
E 1 120 TYR 120 66  66  TYR TYR E . n 
E 1 121 TRP 121 67  67  TRP TRP E . n 
E 1 122 ARG 122 68  68  ARG ARG E . n 
E 1 123 ASP 123 69  69  ASP ASP E . n 
E 1 124 LYS 124 70  70  LYS LYS E . n 
E 1 125 ARG 125 71  71  ARG ARG E . n 
E 1 126 LEU 126 72  72  LEU LEU E . n 
E 1 127 ALA 127 73  73  ALA ALA E . n 
E 1 128 TYR 128 74  74  TYR TYR E . n 
E 1 129 SER 129 75  75  SER SER E . n 
E 1 130 GLY 130 76  76  GLY GLY E . n 
E 1 131 ILE 131 77  77  ILE ILE E . n 
E 1 132 PRO 132 78  78  PRO PRO E . n 
E 1 133 LEU 133 79  79  LEU LEU E . n 
E 1 134 ASN 134 80  80  ASN ASN E . n 
E 1 135 LEU 135 81  81  LEU LEU E . n 
E 1 136 THR 136 82  82  THR THR E . n 
E 1 137 LEU 137 83  83  LEU LEU E . n 
E 1 138 ASP 138 84  84  ASP ASP E . n 
E 1 139 ASN 139 85  85  ASN ASN E . n 
E 1 140 ARG 140 86  86  ARG ARG E . n 
E 1 141 VAL 141 87  87  VAL VAL E . n 
E 1 142 ALA 142 88  88  ALA ALA E . n 
E 1 143 ASP 143 89  89  ASP ASP E . n 
E 1 144 GLN 144 90  90  GLN GLN E . n 
E 1 145 LEU 145 91  91  LEU LEU E . n 
E 1 146 TRP 146 92  92  TRP TRP E . n 
E 1 147 VAL 147 93  93  VAL VAL E . n 
E 1 148 PRO 148 94  94  PRO PRO E . n 
E 1 149 ASP 149 95  95  ASP ASP E . n 
E 1 150 THR 150 96  96  THR THR E . n 
E 1 151 TYR 151 97  97  TYR TYR E . n 
E 1 152 PHE 152 98  98  PHE PHE E . n 
E 1 153 LEU 153 99  99  LEU LEU E . n 
E 1 154 ASN 154 100 100 ASN ASN E . n 
E 1 155 ASP 155 101 101 ASP ASP E . n 
E 1 156 LYS 156 102 102 LYS LYS E . n 
E 1 157 LYS 157 103 103 LYS LYS E . n 
E 1 158 SER 158 104 104 SER SER E . n 
E 1 159 PHE 159 105 105 PHE PHE E . n 
E 1 160 VAL 160 106 106 VAL VAL E . n 
E 1 161 HIS 161 107 107 HIS HIS E . n 
E 1 162 GLY 162 108 108 GLY GLY E . n 
E 1 163 VAL 163 109 109 VAL VAL E . n 
E 1 164 THR 164 110 110 THR THR E . n 
E 1 165 VAL 165 111 111 VAL VAL E . n 
E 1 166 LYS 166 112 112 LYS LYS E . n 
E 1 167 ASN 167 113 113 ASN ASN E . n 
E 1 168 ARG 168 114 114 ARG ARG E . n 
E 1 169 MET 169 115 115 MET MET E . n 
E 1 170 ILE 170 116 116 ILE ILE E . n 
E 1 171 ARG 171 117 117 ARG ARG E . n 
E 1 172 LEU 172 118 118 LEU LEU E . n 
E 1 173 HIS 173 119 119 HIS HIS E . n 
E 1 174 PRO 174 120 120 PRO PRO E . n 
E 1 175 ASP 175 121 121 ASP ASP E . n 
E 1 176 GLY 176 122 122 GLY GLY E . n 
E 1 177 THR 177 123 123 THR THR E . n 
E 1 178 VAL 178 124 124 VAL VAL E . n 
E 1 179 LEU 179 125 125 LEU LEU E . n 
E 1 180 TYR 180 126 126 TYR TYR E . n 
E 1 181 GLY 181 127 127 GLY GLY E . n 
E 1 182 LEU 182 128 128 LEU LEU E . n 
E 1 183 ARG 183 129 129 ARG ARG E . n 
E 1 184 ILE 184 130 130 ILE ILE E . n 
E 1 185 THR 185 131 131 THR THR E . n 
E 1 186 THR 186 132 132 THR THR E . n 
E 1 187 THR 187 133 133 THR THR E . n 
E 1 188 ALA 188 134 134 ALA ALA E . n 
E 1 189 ALA 189 135 135 ALA ALA E . n 
E 1 190 CYS 190 136 136 CYS CYS E . n 
E 1 191 MET 191 137 137 MET MET E . n 
E 1 192 MET 192 138 138 MET MET E . n 
E 1 193 ASP 193 139 139 ASP ASP E . n 
E 1 194 LEU 194 140 140 LEU LEU E . n 
E 1 195 ARG 195 141 141 ARG ARG E . n 
E 1 196 ARG 196 142 142 ARG ARG E . n 
E 1 197 TYR 197 143 143 TYR TYR E . n 
E 1 198 PRO 198 144 144 PRO PRO E . n 
E 1 199 LEU 199 145 145 LEU LEU E . n 
E 1 200 ASP 200 146 146 ASP ASP E . n 
E 1 201 GLU 201 147 147 GLU GLU E . n 
E 1 202 GLN 202 148 148 GLN GLN E . n 
E 1 203 ASN 203 149 149 ASN ASN E . n 
E 1 204 CYS 204 150 150 CYS CYS E . n 
E 1 205 THR 205 151 151 THR THR E . n 
E 1 206 LEU 206 152 152 LEU LEU E . n 
E 1 207 GLU 207 153 153 GLU GLU E . n 
E 1 208 ILE 208 154 154 ILE ILE E . n 
E 1 209 GLU 209 155 155 GLU GLU E . n 
E 1 210 SER 210 156 156 SER SER E . n 
E 1 211 TYR 211 157 157 TYR TYR E . n 
E 1 212 GLY 212 158 158 GLY GLY E . n 
E 1 213 TYR 213 159 159 TYR TYR E . n 
E 1 214 THR 214 160 160 THR THR E . n 
E 1 215 THR 215 161 161 THR THR E . n 
E 1 216 ASP 216 162 162 ASP ASP E . n 
E 1 217 ASP 217 163 163 ASP ASP E . n 
E 1 218 ILE 218 164 164 ILE ILE E . n 
E 1 219 GLU 219 165 165 GLU GLU E . n 
E 1 220 PHE 220 166 166 PHE PHE E . n 
E 1 221 TYR 221 167 167 TYR TYR E . n 
E 1 222 TRP 222 168 168 TRP TRP E . n 
E 1 223 ARG 223 169 169 ARG ARG E . n 
E 1 224 GLY 224 170 170 GLY GLY E . n 
E 1 225 GLY 225 171 171 GLY GLY E . n 
E 1 226 ASP 226 172 172 ASP ASP E . n 
E 1 227 LYS 227 173 173 LYS LYS E . n 
E 1 228 ALA 228 174 174 ALA ALA E . n 
E 1 229 VAL 229 175 175 VAL VAL E . n 
E 1 230 THR 230 176 176 THR THR E . n 
E 1 231 GLY 231 177 177 GLY GLY E . n 
E 1 232 VAL 232 178 178 VAL VAL E . n 
E 1 233 GLU 233 179 179 GLU GLU E . n 
E 1 234 ARG 234 180 180 ARG ARG E . n 
E 1 235 ILE 235 181 181 ILE ILE E . n 
E 1 236 GLU 236 182 182 GLU GLU E . n 
E 1 237 LEU 237 183 183 LEU LEU E . n 
E 1 238 PRO 238 184 184 PRO PRO E . n 
E 1 239 GLN 239 185 185 GLN GLN E . n 
E 1 240 PHE 240 186 186 PHE PHE E . n 
E 1 241 SER 241 187 187 SER SER E . n 
E 1 242 ILE 242 188 188 ILE ILE E . n 
E 1 243 VAL 243 189 189 VAL VAL E . n 
E 1 244 GLU 244 190 190 GLU GLU E . n 
E 1 245 HIS 245 191 191 HIS HIS E . n 
E 1 246 ARG 246 192 192 ARG ARG E . n 
E 1 247 LEU 247 193 193 LEU LEU E . n 
E 1 248 VAL 248 194 194 VAL VAL E . n 
E 1 249 SER 249 195 195 SER SER E . n 
E 1 250 ARG 250 196 196 ARG ARG E . n 
E 1 251 ASN 251 197 197 ASN ASN E . n 
E 1 252 VAL 252 198 198 VAL VAL E . n 
E 1 253 VAL 253 199 199 VAL VAL E . n 
E 1 254 PHE 254 200 200 PHE PHE E . n 
E 1 255 ALA 255 201 201 ALA ALA E . n 
E 1 256 THR 256 202 202 THR THR E . n 
E 1 257 GLY 257 203 203 GLY GLY E . n 
E 1 258 ALA 258 204 204 ALA ALA E . n 
E 1 259 TYR 259 205 205 TYR TYR E . n 
E 1 260 PRO 260 206 206 PRO PRO E . n 
E 1 261 ARG 261 207 207 ARG ARG E . n 
E 1 262 LEU 262 208 208 LEU LEU E . n 
E 1 263 SER 263 209 209 SER SER E . n 
E 1 264 LEU 264 210 210 LEU LEU E . n 
E 1 265 SER 265 211 211 SER SER E . n 
E 1 266 PHE 266 212 212 PHE PHE E . n 
E 1 267 ARG 267 213 213 ARG ARG E . n 
E 1 268 LEU 268 214 214 LEU LEU E . n 
E 1 269 LYS 269 215 215 LYS LYS E . n 
E 1 270 ARG 270 216 216 ARG ARG E . n 
E 1 271 ASN 271 217 217 ASN ASN E . n 
E 1 272 ILE 272 218 218 ILE ILE E . n 
E 1 273 GLY 273 219 219 GLY GLY E . n 
E 1 274 TYR 274 220 220 TYR TYR E . n 
E 1 275 PHE 275 221 221 PHE PHE E . n 
E 1 276 ILE 276 222 222 ILE ILE E . n 
E 1 277 LEU 277 223 223 LEU LEU E . n 
E 1 278 GLN 278 224 224 GLN GLN E . n 
E 1 279 THR 279 225 225 THR THR E . n 
E 1 280 TYR 280 226 226 TYR TYR E . n 
E 1 281 MET 281 227 227 MET MET E . n 
E 1 282 PRO 282 228 228 PRO PRO E . n 
E 1 283 SER 283 229 229 SER SER E . n 
E 1 284 ILE 284 230 230 ILE ILE E . n 
E 1 285 LEU 285 231 231 LEU LEU E . n 
E 1 286 ILE 286 232 232 ILE ILE E . n 
E 1 287 THR 287 233 233 THR THR E . n 
E 1 288 ILE 288 234 234 ILE ILE E . n 
E 1 289 LEU 289 235 235 LEU LEU E . n 
E 1 290 SER 290 236 236 SER SER E . n 
E 1 291 TRP 291 237 237 TRP TRP E . n 
E 1 292 VAL 292 238 238 VAL VAL E . n 
E 1 293 SER 293 239 239 SER SER E . n 
E 1 294 PHE 294 240 240 PHE PHE E . n 
E 1 295 TRP 295 241 241 TRP TRP E . n 
E 1 296 ILE 296 242 242 ILE ILE E . n 
E 1 297 ASN 297 243 243 ASN ASN E . n 
E 1 298 TYR 298 244 244 TYR TYR E . n 
E 1 299 ASP 299 245 245 ASP ASP E . n 
E 1 300 ALA 300 246 246 ALA ALA E . n 
E 1 301 SER 301 247 247 SER SER E . n 
E 1 302 ALA 302 248 248 ALA ALA E . n 
E 1 303 ALA 303 249 249 ALA ALA E . n 
E 1 304 ARG 304 250 250 ARG ARG E . n 
E 1 305 VAL 305 251 251 VAL VAL E . n 
E 1 306 ALA 306 252 252 ALA ALA E . n 
E 1 307 LEU 307 253 253 LEU LEU E . n 
E 1 308 GLY 308 254 254 GLY GLY E . n 
E 1 309 ILE 309 255 255 ILE ILE E . n 
E 1 310 THR 310 256 256 THR THR E . n 
E 1 311 THR 311 257 257 THR THR E . n 
E 1 312 VAL 312 258 258 VAL VAL E . n 
E 1 313 LEU 313 259 259 LEU LEU E . n 
E 1 314 THR 314 260 260 THR THR E . n 
E 1 315 MET 315 261 261 MET MET E . n 
E 1 316 THR 316 262 262 THR THR E . n 
E 1 317 THR 317 263 263 THR THR E . n 
E 1 318 ILE 318 264 264 ILE ILE E . n 
E 1 319 ASN 319 265 265 ASN ASN E . n 
E 1 320 THR 320 266 266 THR THR E . n 
E 1 321 HIS 321 267 267 HIS HIS E . n 
E 1 322 LEU 322 268 268 LEU LEU E . n 
E 1 323 ARG 323 269 269 ARG ARG E . n 
E 1 324 GLU 324 270 270 GLU GLU E . n 
E 1 325 THR 325 271 271 THR THR E . n 
E 1 326 LEU 326 272 272 LEU LEU E . n 
E 1 327 PRO 327 273 273 PRO PRO E . n 
E 1 328 LYS 328 274 274 LYS LYS E . n 
E 1 329 ILE 329 275 275 ILE ILE E . n 
E 1 330 PRO 330 276 276 PRO PRO E . n 
E 1 331 TYR 331 277 277 TYR TYR E . n 
E 1 332 VAL 332 278 278 VAL VAL E . n 
E 1 333 LYS 333 279 279 LYS LYS E . n 
E 1 334 ALA 334 280 280 ALA ALA E . n 
E 1 335 ILE 335 281 281 ILE ILE E . n 
E 1 336 ASP 336 282 282 ASP ASP E . n 
E 1 337 MET 337 283 283 MET MET E . n 
E 1 338 TYR 338 284 284 TYR TYR E . n 
E 1 339 LEU 339 285 285 LEU LEU E . n 
E 1 340 MET 340 286 286 MET MET E . n 
E 1 341 GLY 341 287 287 GLY GLY E . n 
E 1 342 CYS 342 288 288 CYS CYS E . n 
E 1 343 PHE 343 289 289 PHE PHE E . n 
E 1 344 VAL 344 290 290 VAL VAL E . n 
E 1 345 PHE 345 291 291 PHE PHE E . n 
E 1 346 VAL 346 292 292 VAL VAL E . n 
E 1 347 PHE 347 293 293 PHE PHE E . n 
E 1 348 LEU 348 294 294 LEU LEU E . n 
E 1 349 ALA 349 295 295 ALA ALA E . n 
E 1 350 LEU 350 296 296 LEU LEU E . n 
E 1 351 LEU 351 297 297 LEU LEU E . n 
E 1 352 GLU 352 298 298 GLU GLU E . n 
E 1 353 TYR 353 299 299 TYR TYR E . n 
E 1 354 ALA 354 300 300 ALA ALA E . n 
E 1 355 PHE 355 301 301 PHE PHE E . n 
E 1 356 VAL 356 302 302 VAL VAL E . n 
E 1 357 ASN 357 303 303 ASN ASN E . n 
E 1 358 TYR 358 304 304 TYR TYR E . n 
E 1 359 ILE 359 305 305 ILE ILE E . n 
E 1 360 PHE 360 306 306 PHE PHE E . n 
E 1 361 PHE 361 307 307 PHE PHE E . n 
E 1 362 SER 362 308 308 SER SER E . n 
E 1 363 GLN 363 309 309 GLN GLN E . n 
E 1 364 PRO 364 310 310 PRO PRO E . n 
E 1 365 ALA 365 311 311 ALA ALA E . n 
E 1 366 ARG 366 312 312 ARG ARG E . n 
E 1 367 ALA 367 313 313 ALA ALA E . n 
E 1 368 ALA 368 314 314 ALA ALA E . n 
E 1 369 ALA 369 422 422 ALA ALA E . n 
E 1 370 ILE 370 423 423 ILE ILE E . n 
E 1 371 ASP 371 424 424 ASP ASP E . n 
E 1 372 ARG 372 425 425 ARG ARG E . n 
E 1 373 TRP 373 426 426 TRP TRP E . n 
E 1 374 SER 374 427 427 SER SER E . n 
E 1 375 ARG 375 428 428 ARG ARG E . n 
E 1 376 ILE 376 429 429 ILE ILE E . n 
E 1 377 VAL 377 430 430 VAL VAL E . n 
E 1 378 PHE 378 431 431 PHE PHE E . n 
E 1 379 PRO 379 432 432 PRO PRO E . n 
E 1 380 PHE 380 433 433 PHE PHE E . n 
E 1 381 THR 381 434 434 THR THR E . n 
E 1 382 PHE 382 435 435 PHE PHE E . n 
E 1 383 SER 383 436 436 SER SER E . n 
E 1 384 LEU 384 437 437 LEU LEU E . n 
E 1 385 PHE 385 438 438 PHE PHE E . n 
E 1 386 ASN 386 439 439 ASN ASN E . n 
E 1 387 LEU 387 440 440 LEU LEU E . n 
E 1 388 VAL 388 441 441 VAL VAL E . n 
E 1 389 TYR 389 442 442 TYR TYR E . n 
E 1 390 TRP 390 443 443 TRP TRP E . n 
E 1 391 LEU 391 444 444 LEU LEU E . n 
E 1 392 TYR 392 445 445 TYR TYR E . n 
E 1 393 TYR 393 446 446 TYR TYR E . n 
E 1 394 VAL 394 447 447 VAL VAL E . n 
E 1 395 ASN 395 448 ?   ?   ?   E . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
F 2 NAG 1 a NAG 1 a NAG 1 n 
F 2 NAG 2 a NAG 2 a NAG 2 n 
F 2 BMA 3 a BMA 3 a BMA 3 n 
F 2 MAN 4 a MAN 4 a MAN 4 n 
F 2 MAN 5 a MAN 5 a MAN 5 n 
G 3 NAG 1 F NAG 1 a NAG 6 n 
G 3 NAG 2 F NAG 2 a NAG 7 n 
H 2 NAG 1 b NAG 1 b NAG 1 n 
H 2 NAG 2 b NAG 2 b NAG 2 n 
H 2 BMA 3 b BMA 3 b BMA 3 n 
H 2 MAN 4 b MAN 4 b MAN 4 n 
H 2 MAN 5 b MAN 5 b MAN 5 n 
I 3 NAG 1 G NAG 1 b NAG 6 n 
I 3 NAG 2 G NAG 2 b NAG 7 n 
J 2 NAG 1 c NAG 1 c NAG 1 n 
J 2 NAG 2 c NAG 2 c NAG 2 n 
J 2 BMA 3 c BMA 3 c BMA 3 n 
J 2 MAN 4 c MAN 4 c MAN 4 n 
J 2 MAN 5 c MAN 5 c MAN 5 n 
K 3 NAG 1 H NAG 1 c NAG 6 n 
K 3 NAG 2 H NAG 2 c NAG 7 n 
L 2 NAG 1 d NAG 1 d NAG 1 n 
L 2 NAG 2 d NAG 2 d NAG 2 n 
L 2 BMA 3 d BMA 3 d BMA 3 n 
L 2 MAN 4 d MAN 4 d MAN 4 n 
L 2 MAN 5 d MAN 5 d MAN 5 n 
M 3 NAG 1 I NAG 1 d NAG 6 n 
M 3 NAG 2 I NAG 2 d NAG 7 n 
N 2 NAG 1 e NAG 1 e NAG 1 n 
N 2 NAG 2 e NAG 2 e NAG 2 n 
N 2 BMA 3 e BMA 3 e BMA 3 n 
N 2 MAN 4 e MAN 4 e MAN 4 n 
N 2 MAN 5 e MAN 5 e MAN 5 n 
O 3 NAG 1 J NAG 1 e NAG 6 n 
O 3 NAG 2 J NAG 2 e NAG 7 n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        HSM 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   HSM 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
P 4 NAG 1 501 8 NAG NAG A . 
Q 5 HSM 1 502 1 HSM HSM A . 
R 5 HSM 1 503 4 HSM HSM A . 
S 5 HSM 1 501 2 HSM HSM B . 
T 4 NAG 1 502 8 NAG NAG B . 
U 4 NAG 1 501 8 NAG NAG C . 
V 5 HSM 1 501 3 HSM HSM D . 
W 4 NAG 1 502 8 NAG NAG D . 
X 4 NAG 1 501 8 NAG NAG E . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FF1 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FF1 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FF1 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9FF1 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 14774 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.453 ? 20120 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 9.779 ? 5483  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.040 ? 2367  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003 ? 2482  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9FF1 
_struct.title                        
'Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric desensitised state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FF1 
_struct_keywords.text            'GABA, neurotransmission, gating cycle, time-resolved cryo-EM, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 2 ? 
G N N 3 ? 
H N N 2 ? 
I N N 3 ? 
J N N 2 ? 
K N N 3 ? 
L N N 2 ? 
M N N 3 ? 
N N N 2 ? 
O N N 3 ? 
P N N 4 ? 
Q N N 5 ? 
R N N 5 ? 
S N N 5 ? 
T N N 4 ? 
U N N 4 ? 
V N N 5 ? 
W N N 4 ? 
X N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GBRB3_HUMAN P28472 ? 1 
;QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLN
LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYT
TDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF
WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF
;
26  
2 UNP GBRB3_HUMAN P28472 ? 1 AIDRWSRIVFPFTFSLFNLVYWLYYVN 447 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1  1 9FF1 A 55  ? 361 ? P28472 26  ? 332 ? 1   307 
2  2 9FF1 A 369 ? 395 ? P28472 447 ? 473 ? 422 448 
3  1 9FF1 B 55  ? 361 ? P28472 26  ? 332 ? 1   307 
4  2 9FF1 B 369 ? 395 ? P28472 447 ? 473 ? 422 448 
5  1 9FF1 C 55  ? 361 ? P28472 26  ? 332 ? 1   307 
6  2 9FF1 C 369 ? 395 ? P28472 447 ? 473 ? 422 448 
7  1 9FF1 D 55  ? 361 ? P28472 26  ? 332 ? 1   307 
8  2 9FF1 D 369 ? 395 ? P28472 447 ? 473 ? 422 448 
9  1 9FF1 E 55  ? 361 ? P28472 26  ? 332 ? 1   307 
10 2 9FF1 E 369 ? 395 ? P28472 447 ? 473 ? 422 448 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9FF1 MET A 1   ? UNP P28472 ? ? 'initiating methionine' -53 1   
1 9FF1 ASP A 2   ? UNP P28472 ? ? 'expression tag'        -52 2   
1 9FF1 GLU A 3   ? UNP P28472 ? ? 'expression tag'        -51 3   
1 9FF1 LYS A 4   ? UNP P28472 ? ? 'expression tag'        -50 4   
1 9FF1 THR A 5   ? UNP P28472 ? ? 'expression tag'        -49 5   
1 9FF1 THR A 6   ? UNP P28472 ? ? 'expression tag'        -48 6   
1 9FF1 GLY A 7   ? UNP P28472 ? ? 'expression tag'        -47 7   
1 9FF1 TRP A 8   ? UNP P28472 ? ? 'expression tag'        -46 8   
1 9FF1 ARG A 9   ? UNP P28472 ? ? 'expression tag'        -45 9   
1 9FF1 GLY A 10  ? UNP P28472 ? ? 'expression tag'        -44 10  
1 9FF1 GLY A 11  ? UNP P28472 ? ? 'expression tag'        -43 11  
1 9FF1 HIS A 12  ? UNP P28472 ? ? 'expression tag'        -42 12  
1 9FF1 VAL A 13  ? UNP P28472 ? ? 'expression tag'        -41 13  
1 9FF1 VAL A 14  ? UNP P28472 ? ? 'expression tag'        -40 14  
1 9FF1 GLU A 15  ? UNP P28472 ? ? 'expression tag'        -39 15  
1 9FF1 GLY A 16  ? UNP P28472 ? ? 'expression tag'        -38 16  
1 9FF1 LEU A 17  ? UNP P28472 ? ? 'expression tag'        -37 17  
1 9FF1 ALA A 18  ? UNP P28472 ? ? 'expression tag'        -36 18  
1 9FF1 GLY A 19  ? UNP P28472 ? ? 'expression tag'        -35 19  
1 9FF1 GLU A 20  ? UNP P28472 ? ? 'expression tag'        -34 20  
1 9FF1 LEU A 21  ? UNP P28472 ? ? 'expression tag'        -33 21  
1 9FF1 GLU A 22  ? UNP P28472 ? ? 'expression tag'        -32 22  
1 9FF1 GLN A 23  ? UNP P28472 ? ? 'expression tag'        -31 23  
1 9FF1 LEU A 24  ? UNP P28472 ? ? 'expression tag'        -30 24  
1 9FF1 ARG A 25  ? UNP P28472 ? ? 'expression tag'        -29 25  
1 9FF1 ALA A 26  ? UNP P28472 ? ? 'expression tag'        -28 26  
1 9FF1 ARG A 27  ? UNP P28472 ? ? 'expression tag'        -27 27  
1 9FF1 LEU A 28  ? UNP P28472 ? ? 'expression tag'        -26 28  
1 9FF1 GLU A 29  ? UNP P28472 ? ? 'expression tag'        -25 29  
1 9FF1 HIS A 30  ? UNP P28472 ? ? 'expression tag'        -24 30  
1 9FF1 HIS A 31  ? UNP P28472 ? ? 'expression tag'        -23 31  
1 9FF1 PRO A 32  ? UNP P28472 ? ? 'expression tag'        -22 32  
1 9FF1 GLN A 33  ? UNP P28472 ? ? 'expression tag'        -21 33  
1 9FF1 GLY A 34  ? UNP P28472 ? ? 'expression tag'        -20 34  
1 9FF1 GLN A 35  ? UNP P28472 ? ? 'expression tag'        -19 35  
1 9FF1 ARG A 36  ? UNP P28472 ? ? 'expression tag'        -18 36  
1 9FF1 GLU A 37  ? UNP P28472 ? ? 'expression tag'        -17 37  
1 9FF1 PRO A 38  ? UNP P28472 ? ? 'expression tag'        -16 38  
1 9FF1 ASP A 39  ? UNP P28472 ? ? 'expression tag'        -15 39  
1 9FF1 TYR A 40  ? UNP P28472 ? ? 'expression tag'        -14 40  
1 9FF1 ASP A 41  ? UNP P28472 ? ? 'expression tag'        -13 41  
1 9FF1 ILE A 42  ? UNP P28472 ? ? 'expression tag'        -12 42  
1 9FF1 PRO A 43  ? UNP P28472 ? ? 'expression tag'        -11 43  
1 9FF1 THR A 44  ? UNP P28472 ? ? 'expression tag'        -10 44  
1 9FF1 THR A 45  ? UNP P28472 ? ? 'expression tag'        -9  45  
1 9FF1 GLU A 46  ? UNP P28472 ? ? 'expression tag'        -8  46  
1 9FF1 ASN A 47  ? UNP P28472 ? ? 'expression tag'        -7  47  
1 9FF1 LEU A 48  ? UNP P28472 ? ? 'expression tag'        -6  48  
1 9FF1 TYR A 49  ? UNP P28472 ? ? 'expression tag'        -5  49  
1 9FF1 PHE A 50  ? UNP P28472 ? ? 'expression tag'        -4  50  
1 9FF1 GLN A 51  ? UNP P28472 ? ? 'expression tag'        -3  51  
1 9FF1 GLY A 52  ? UNP P28472 ? ? 'expression tag'        -2  52  
1 9FF1 THR A 53  ? UNP P28472 ? ? 'expression tag'        -1  53  
1 9FF1 GLY A 54  ? UNP P28472 ? ? 'expression tag'        0   54  
1 9FF1 SER A 362 ? UNP P28472 ? ? linker                  308 55  
1 9FF1 GLN A 363 ? UNP P28472 ? ? linker                  309 56  
1 9FF1 PRO A 364 ? UNP P28472 ? ? linker                  310 57  
1 9FF1 ALA A 365 ? UNP P28472 ? ? linker                  311 58  
1 9FF1 ARG A 366 ? UNP P28472 ? ? linker                  312 59  
1 9FF1 ALA A 367 ? UNP P28472 ? ? linker                  313 60  
1 9FF1 ALA A 368 ? UNP P28472 ? ? linker                  314 61  
3 9FF1 MET B 1   ? UNP P28472 ? ? 'initiating methionine' -53 62  
3 9FF1 ASP B 2   ? UNP P28472 ? ? 'expression tag'        -52 63  
3 9FF1 GLU B 3   ? UNP P28472 ? ? 'expression tag'        -51 64  
3 9FF1 LYS B 4   ? UNP P28472 ? ? 'expression tag'        -50 65  
3 9FF1 THR B 5   ? UNP P28472 ? ? 'expression tag'        -49 66  
3 9FF1 THR B 6   ? UNP P28472 ? ? 'expression tag'        -48 67  
3 9FF1 GLY B 7   ? UNP P28472 ? ? 'expression tag'        -47 68  
3 9FF1 TRP B 8   ? UNP P28472 ? ? 'expression tag'        -46 69  
3 9FF1 ARG B 9   ? UNP P28472 ? ? 'expression tag'        -45 70  
3 9FF1 GLY B 10  ? UNP P28472 ? ? 'expression tag'        -44 71  
3 9FF1 GLY B 11  ? UNP P28472 ? ? 'expression tag'        -43 72  
3 9FF1 HIS B 12  ? UNP P28472 ? ? 'expression tag'        -42 73  
3 9FF1 VAL B 13  ? UNP P28472 ? ? 'expression tag'        -41 74  
3 9FF1 VAL B 14  ? UNP P28472 ? ? 'expression tag'        -40 75  
3 9FF1 GLU B 15  ? UNP P28472 ? ? 'expression tag'        -39 76  
3 9FF1 GLY B 16  ? UNP P28472 ? ? 'expression tag'        -38 77  
3 9FF1 LEU B 17  ? UNP P28472 ? ? 'expression tag'        -37 78  
3 9FF1 ALA B 18  ? UNP P28472 ? ? 'expression tag'        -36 79  
3 9FF1 GLY B 19  ? UNP P28472 ? ? 'expression tag'        -35 80  
3 9FF1 GLU B 20  ? UNP P28472 ? ? 'expression tag'        -34 81  
3 9FF1 LEU B 21  ? UNP P28472 ? ? 'expression tag'        -33 82  
3 9FF1 GLU B 22  ? UNP P28472 ? ? 'expression tag'        -32 83  
3 9FF1 GLN B 23  ? UNP P28472 ? ? 'expression tag'        -31 84  
3 9FF1 LEU B 24  ? UNP P28472 ? ? 'expression tag'        -30 85  
3 9FF1 ARG B 25  ? UNP P28472 ? ? 'expression tag'        -29 86  
3 9FF1 ALA B 26  ? UNP P28472 ? ? 'expression tag'        -28 87  
3 9FF1 ARG B 27  ? UNP P28472 ? ? 'expression tag'        -27 88  
3 9FF1 LEU B 28  ? UNP P28472 ? ? 'expression tag'        -26 89  
3 9FF1 GLU B 29  ? UNP P28472 ? ? 'expression tag'        -25 90  
3 9FF1 HIS B 30  ? UNP P28472 ? ? 'expression tag'        -24 91  
3 9FF1 HIS B 31  ? UNP P28472 ? ? 'expression tag'        -23 92  
3 9FF1 PRO B 32  ? UNP P28472 ? ? 'expression tag'        -22 93  
3 9FF1 GLN B 33  ? UNP P28472 ? ? 'expression tag'        -21 94  
3 9FF1 GLY B 34  ? UNP P28472 ? ? 'expression tag'        -20 95  
3 9FF1 GLN B 35  ? UNP P28472 ? ? 'expression tag'        -19 96  
3 9FF1 ARG B 36  ? UNP P28472 ? ? 'expression tag'        -18 97  
3 9FF1 GLU B 37  ? UNP P28472 ? ? 'expression tag'        -17 98  
3 9FF1 PRO B 38  ? UNP P28472 ? ? 'expression tag'        -16 99  
3 9FF1 ASP B 39  ? UNP P28472 ? ? 'expression tag'        -15 100 
3 9FF1 TYR B 40  ? UNP P28472 ? ? 'expression tag'        -14 101 
3 9FF1 ASP B 41  ? UNP P28472 ? ? 'expression tag'        -13 102 
3 9FF1 ILE B 42  ? UNP P28472 ? ? 'expression tag'        -12 103 
3 9FF1 PRO B 43  ? UNP P28472 ? ? 'expression tag'        -11 104 
3 9FF1 THR B 44  ? UNP P28472 ? ? 'expression tag'        -10 105 
3 9FF1 THR B 45  ? UNP P28472 ? ? 'expression tag'        -9  106 
3 9FF1 GLU B 46  ? UNP P28472 ? ? 'expression tag'        -8  107 
3 9FF1 ASN B 47  ? UNP P28472 ? ? 'expression tag'        -7  108 
3 9FF1 LEU B 48  ? UNP P28472 ? ? 'expression tag'        -6  109 
3 9FF1 TYR B 49  ? UNP P28472 ? ? 'expression tag'        -5  110 
3 9FF1 PHE B 50  ? UNP P28472 ? ? 'expression tag'        -4  111 
3 9FF1 GLN B 51  ? UNP P28472 ? ? 'expression tag'        -3  112 
3 9FF1 GLY B 52  ? UNP P28472 ? ? 'expression tag'        -2  113 
3 9FF1 THR B 53  ? UNP P28472 ? ? 'expression tag'        -1  114 
3 9FF1 GLY B 54  ? UNP P28472 ? ? 'expression tag'        0   115 
3 9FF1 SER B 362 ? UNP P28472 ? ? linker                  308 116 
3 9FF1 GLN B 363 ? UNP P28472 ? ? linker                  309 117 
3 9FF1 PRO B 364 ? UNP P28472 ? ? linker                  310 118 
3 9FF1 ALA B 365 ? UNP P28472 ? ? linker                  311 119 
3 9FF1 ARG B 366 ? UNP P28472 ? ? linker                  312 120 
3 9FF1 ALA B 367 ? UNP P28472 ? ? linker                  313 121 
3 9FF1 ALA B 368 ? UNP P28472 ? ? linker                  314 122 
5 9FF1 MET C 1   ? UNP P28472 ? ? 'initiating methionine' -53 123 
5 9FF1 ASP C 2   ? UNP P28472 ? ? 'expression tag'        -52 124 
5 9FF1 GLU C 3   ? UNP P28472 ? ? 'expression tag'        -51 125 
5 9FF1 LYS C 4   ? UNP P28472 ? ? 'expression tag'        -50 126 
5 9FF1 THR C 5   ? UNP P28472 ? ? 'expression tag'        -49 127 
5 9FF1 THR C 6   ? UNP P28472 ? ? 'expression tag'        -48 128 
5 9FF1 GLY C 7   ? UNP P28472 ? ? 'expression tag'        -47 129 
5 9FF1 TRP C 8   ? UNP P28472 ? ? 'expression tag'        -46 130 
5 9FF1 ARG C 9   ? UNP P28472 ? ? 'expression tag'        -45 131 
5 9FF1 GLY C 10  ? UNP P28472 ? ? 'expression tag'        -44 132 
5 9FF1 GLY C 11  ? UNP P28472 ? ? 'expression tag'        -43 133 
5 9FF1 HIS C 12  ? UNP P28472 ? ? 'expression tag'        -42 134 
5 9FF1 VAL C 13  ? UNP P28472 ? ? 'expression tag'        -41 135 
5 9FF1 VAL C 14  ? UNP P28472 ? ? 'expression tag'        -40 136 
5 9FF1 GLU C 15  ? UNP P28472 ? ? 'expression tag'        -39 137 
5 9FF1 GLY C 16  ? UNP P28472 ? ? 'expression tag'        -38 138 
5 9FF1 LEU C 17  ? UNP P28472 ? ? 'expression tag'        -37 139 
5 9FF1 ALA C 18  ? UNP P28472 ? ? 'expression tag'        -36 140 
5 9FF1 GLY C 19  ? UNP P28472 ? ? 'expression tag'        -35 141 
5 9FF1 GLU C 20  ? UNP P28472 ? ? 'expression tag'        -34 142 
5 9FF1 LEU C 21  ? UNP P28472 ? ? 'expression tag'        -33 143 
5 9FF1 GLU C 22  ? UNP P28472 ? ? 'expression tag'        -32 144 
5 9FF1 GLN C 23  ? UNP P28472 ? ? 'expression tag'        -31 145 
5 9FF1 LEU C 24  ? UNP P28472 ? ? 'expression tag'        -30 146 
5 9FF1 ARG C 25  ? UNP P28472 ? ? 'expression tag'        -29 147 
5 9FF1 ALA C 26  ? UNP P28472 ? ? 'expression tag'        -28 148 
5 9FF1 ARG C 27  ? UNP P28472 ? ? 'expression tag'        -27 149 
5 9FF1 LEU C 28  ? UNP P28472 ? ? 'expression tag'        -26 150 
5 9FF1 GLU C 29  ? UNP P28472 ? ? 'expression tag'        -25 151 
5 9FF1 HIS C 30  ? UNP P28472 ? ? 'expression tag'        -24 152 
5 9FF1 HIS C 31  ? UNP P28472 ? ? 'expression tag'        -23 153 
5 9FF1 PRO C 32  ? UNP P28472 ? ? 'expression tag'        -22 154 
5 9FF1 GLN C 33  ? UNP P28472 ? ? 'expression tag'        -21 155 
5 9FF1 GLY C 34  ? UNP P28472 ? ? 'expression tag'        -20 156 
5 9FF1 GLN C 35  ? UNP P28472 ? ? 'expression tag'        -19 157 
5 9FF1 ARG C 36  ? UNP P28472 ? ? 'expression tag'        -18 158 
5 9FF1 GLU C 37  ? UNP P28472 ? ? 'expression tag'        -17 159 
5 9FF1 PRO C 38  ? UNP P28472 ? ? 'expression tag'        -16 160 
5 9FF1 ASP C 39  ? UNP P28472 ? ? 'expression tag'        -15 161 
5 9FF1 TYR C 40  ? UNP P28472 ? ? 'expression tag'        -14 162 
5 9FF1 ASP C 41  ? UNP P28472 ? ? 'expression tag'        -13 163 
5 9FF1 ILE C 42  ? UNP P28472 ? ? 'expression tag'        -12 164 
5 9FF1 PRO C 43  ? UNP P28472 ? ? 'expression tag'        -11 165 
5 9FF1 THR C 44  ? UNP P28472 ? ? 'expression tag'        -10 166 
5 9FF1 THR C 45  ? UNP P28472 ? ? 'expression tag'        -9  167 
5 9FF1 GLU C 46  ? UNP P28472 ? ? 'expression tag'        -8  168 
5 9FF1 ASN C 47  ? UNP P28472 ? ? 'expression tag'        -7  169 
5 9FF1 LEU C 48  ? UNP P28472 ? ? 'expression tag'        -6  170 
5 9FF1 TYR C 49  ? UNP P28472 ? ? 'expression tag'        -5  171 
5 9FF1 PHE C 50  ? UNP P28472 ? ? 'expression tag'        -4  172 
5 9FF1 GLN C 51  ? UNP P28472 ? ? 'expression tag'        -3  173 
5 9FF1 GLY C 52  ? UNP P28472 ? ? 'expression tag'        -2  174 
5 9FF1 THR C 53  ? UNP P28472 ? ? 'expression tag'        -1  175 
5 9FF1 GLY C 54  ? UNP P28472 ? ? 'expression tag'        0   176 
5 9FF1 SER C 362 ? UNP P28472 ? ? linker                  308 177 
5 9FF1 GLN C 363 ? UNP P28472 ? ? linker                  309 178 
5 9FF1 PRO C 364 ? UNP P28472 ? ? linker                  310 179 
5 9FF1 ALA C 365 ? UNP P28472 ? ? linker                  311 180 
5 9FF1 ARG C 366 ? UNP P28472 ? ? linker                  312 181 
5 9FF1 ALA C 367 ? UNP P28472 ? ? linker                  313 182 
5 9FF1 ALA C 368 ? UNP P28472 ? ? linker                  314 183 
7 9FF1 MET D 1   ? UNP P28472 ? ? 'initiating methionine' -53 184 
7 9FF1 ASP D 2   ? UNP P28472 ? ? 'expression tag'        -52 185 
7 9FF1 GLU D 3   ? UNP P28472 ? ? 'expression tag'        -51 186 
7 9FF1 LYS D 4   ? UNP P28472 ? ? 'expression tag'        -50 187 
7 9FF1 THR D 5   ? UNP P28472 ? ? 'expression tag'        -49 188 
7 9FF1 THR D 6   ? UNP P28472 ? ? 'expression tag'        -48 189 
7 9FF1 GLY D 7   ? UNP P28472 ? ? 'expression tag'        -47 190 
7 9FF1 TRP D 8   ? UNP P28472 ? ? 'expression tag'        -46 191 
7 9FF1 ARG D 9   ? UNP P28472 ? ? 'expression tag'        -45 192 
7 9FF1 GLY D 10  ? UNP P28472 ? ? 'expression tag'        -44 193 
7 9FF1 GLY D 11  ? UNP P28472 ? ? 'expression tag'        -43 194 
7 9FF1 HIS D 12  ? UNP P28472 ? ? 'expression tag'        -42 195 
7 9FF1 VAL D 13  ? UNP P28472 ? ? 'expression tag'        -41 196 
7 9FF1 VAL D 14  ? UNP P28472 ? ? 'expression tag'        -40 197 
7 9FF1 GLU D 15  ? UNP P28472 ? ? 'expression tag'        -39 198 
7 9FF1 GLY D 16  ? UNP P28472 ? ? 'expression tag'        -38 199 
7 9FF1 LEU D 17  ? UNP P28472 ? ? 'expression tag'        -37 200 
7 9FF1 ALA D 18  ? UNP P28472 ? ? 'expression tag'        -36 201 
7 9FF1 GLY D 19  ? UNP P28472 ? ? 'expression tag'        -35 202 
7 9FF1 GLU D 20  ? UNP P28472 ? ? 'expression tag'        -34 203 
7 9FF1 LEU D 21  ? UNP P28472 ? ? 'expression tag'        -33 204 
7 9FF1 GLU D 22  ? UNP P28472 ? ? 'expression tag'        -32 205 
7 9FF1 GLN D 23  ? UNP P28472 ? ? 'expression tag'        -31 206 
7 9FF1 LEU D 24  ? UNP P28472 ? ? 'expression tag'        -30 207 
7 9FF1 ARG D 25  ? UNP P28472 ? ? 'expression tag'        -29 208 
7 9FF1 ALA D 26  ? UNP P28472 ? ? 'expression tag'        -28 209 
7 9FF1 ARG D 27  ? UNP P28472 ? ? 'expression tag'        -27 210 
7 9FF1 LEU D 28  ? UNP P28472 ? ? 'expression tag'        -26 211 
7 9FF1 GLU D 29  ? UNP P28472 ? ? 'expression tag'        -25 212 
7 9FF1 HIS D 30  ? UNP P28472 ? ? 'expression tag'        -24 213 
7 9FF1 HIS D 31  ? UNP P28472 ? ? 'expression tag'        -23 214 
7 9FF1 PRO D 32  ? UNP P28472 ? ? 'expression tag'        -22 215 
7 9FF1 GLN D 33  ? UNP P28472 ? ? 'expression tag'        -21 216 
7 9FF1 GLY D 34  ? UNP P28472 ? ? 'expression tag'        -20 217 
7 9FF1 GLN D 35  ? UNP P28472 ? ? 'expression tag'        -19 218 
7 9FF1 ARG D 36  ? UNP P28472 ? ? 'expression tag'        -18 219 
7 9FF1 GLU D 37  ? UNP P28472 ? ? 'expression tag'        -17 220 
7 9FF1 PRO D 38  ? UNP P28472 ? ? 'expression tag'        -16 221 
7 9FF1 ASP D 39  ? UNP P28472 ? ? 'expression tag'        -15 222 
7 9FF1 TYR D 40  ? UNP P28472 ? ? 'expression tag'        -14 223 
7 9FF1 ASP D 41  ? UNP P28472 ? ? 'expression tag'        -13 224 
7 9FF1 ILE D 42  ? UNP P28472 ? ? 'expression tag'        -12 225 
7 9FF1 PRO D 43  ? UNP P28472 ? ? 'expression tag'        -11 226 
7 9FF1 THR D 44  ? UNP P28472 ? ? 'expression tag'        -10 227 
7 9FF1 THR D 45  ? UNP P28472 ? ? 'expression tag'        -9  228 
7 9FF1 GLU D 46  ? UNP P28472 ? ? 'expression tag'        -8  229 
7 9FF1 ASN D 47  ? UNP P28472 ? ? 'expression tag'        -7  230 
7 9FF1 LEU D 48  ? UNP P28472 ? ? 'expression tag'        -6  231 
7 9FF1 TYR D 49  ? UNP P28472 ? ? 'expression tag'        -5  232 
7 9FF1 PHE D 50  ? UNP P28472 ? ? 'expression tag'        -4  233 
7 9FF1 GLN D 51  ? UNP P28472 ? ? 'expression tag'        -3  234 
7 9FF1 GLY D 52  ? UNP P28472 ? ? 'expression tag'        -2  235 
7 9FF1 THR D 53  ? UNP P28472 ? ? 'expression tag'        -1  236 
7 9FF1 GLY D 54  ? UNP P28472 ? ? 'expression tag'        0   237 
7 9FF1 SER D 362 ? UNP P28472 ? ? linker                  308 238 
7 9FF1 GLN D 363 ? UNP P28472 ? ? linker                  309 239 
7 9FF1 PRO D 364 ? UNP P28472 ? ? linker                  310 240 
7 9FF1 ALA D 365 ? UNP P28472 ? ? linker                  311 241 
7 9FF1 ARG D 366 ? UNP P28472 ? ? linker                  312 242 
7 9FF1 ALA D 367 ? UNP P28472 ? ? linker                  313 243 
7 9FF1 ALA D 368 ? UNP P28472 ? ? linker                  314 244 
9 9FF1 MET E 1   ? UNP P28472 ? ? 'initiating methionine' -53 245 
9 9FF1 ASP E 2   ? UNP P28472 ? ? 'expression tag'        -52 246 
9 9FF1 GLU E 3   ? UNP P28472 ? ? 'expression tag'        -51 247 
9 9FF1 LYS E 4   ? UNP P28472 ? ? 'expression tag'        -50 248 
9 9FF1 THR E 5   ? UNP P28472 ? ? 'expression tag'        -49 249 
9 9FF1 THR E 6   ? UNP P28472 ? ? 'expression tag'        -48 250 
9 9FF1 GLY E 7   ? UNP P28472 ? ? 'expression tag'        -47 251 
9 9FF1 TRP E 8   ? UNP P28472 ? ? 'expression tag'        -46 252 
9 9FF1 ARG E 9   ? UNP P28472 ? ? 'expression tag'        -45 253 
9 9FF1 GLY E 10  ? UNP P28472 ? ? 'expression tag'        -44 254 
9 9FF1 GLY E 11  ? UNP P28472 ? ? 'expression tag'        -43 255 
9 9FF1 HIS E 12  ? UNP P28472 ? ? 'expression tag'        -42 256 
9 9FF1 VAL E 13  ? UNP P28472 ? ? 'expression tag'        -41 257 
9 9FF1 VAL E 14  ? UNP P28472 ? ? 'expression tag'        -40 258 
9 9FF1 GLU E 15  ? UNP P28472 ? ? 'expression tag'        -39 259 
9 9FF1 GLY E 16  ? UNP P28472 ? ? 'expression tag'        -38 260 
9 9FF1 LEU E 17  ? UNP P28472 ? ? 'expression tag'        -37 261 
9 9FF1 ALA E 18  ? UNP P28472 ? ? 'expression tag'        -36 262 
9 9FF1 GLY E 19  ? UNP P28472 ? ? 'expression tag'        -35 263 
9 9FF1 GLU E 20  ? UNP P28472 ? ? 'expression tag'        -34 264 
9 9FF1 LEU E 21  ? UNP P28472 ? ? 'expression tag'        -33 265 
9 9FF1 GLU E 22  ? UNP P28472 ? ? 'expression tag'        -32 266 
9 9FF1 GLN E 23  ? UNP P28472 ? ? 'expression tag'        -31 267 
9 9FF1 LEU E 24  ? UNP P28472 ? ? 'expression tag'        -30 268 
9 9FF1 ARG E 25  ? UNP P28472 ? ? 'expression tag'        -29 269 
9 9FF1 ALA E 26  ? UNP P28472 ? ? 'expression tag'        -28 270 
9 9FF1 ARG E 27  ? UNP P28472 ? ? 'expression tag'        -27 271 
9 9FF1 LEU E 28  ? UNP P28472 ? ? 'expression tag'        -26 272 
9 9FF1 GLU E 29  ? UNP P28472 ? ? 'expression tag'        -25 273 
9 9FF1 HIS E 30  ? UNP P28472 ? ? 'expression tag'        -24 274 
9 9FF1 HIS E 31  ? UNP P28472 ? ? 'expression tag'        -23 275 
9 9FF1 PRO E 32  ? UNP P28472 ? ? 'expression tag'        -22 276 
9 9FF1 GLN E 33  ? UNP P28472 ? ? 'expression tag'        -21 277 
9 9FF1 GLY E 34  ? UNP P28472 ? ? 'expression tag'        -20 278 
9 9FF1 GLN E 35  ? UNP P28472 ? ? 'expression tag'        -19 279 
9 9FF1 ARG E 36  ? UNP P28472 ? ? 'expression tag'        -18 280 
9 9FF1 GLU E 37  ? UNP P28472 ? ? 'expression tag'        -17 281 
9 9FF1 PRO E 38  ? UNP P28472 ? ? 'expression tag'        -16 282 
9 9FF1 ASP E 39  ? UNP P28472 ? ? 'expression tag'        -15 283 
9 9FF1 TYR E 40  ? UNP P28472 ? ? 'expression tag'        -14 284 
9 9FF1 ASP E 41  ? UNP P28472 ? ? 'expression tag'        -13 285 
9 9FF1 ILE E 42  ? UNP P28472 ? ? 'expression tag'        -12 286 
9 9FF1 PRO E 43  ? UNP P28472 ? ? 'expression tag'        -11 287 
9 9FF1 THR E 44  ? UNP P28472 ? ? 'expression tag'        -10 288 
9 9FF1 THR E 45  ? UNP P28472 ? ? 'expression tag'        -9  289 
9 9FF1 GLU E 46  ? UNP P28472 ? ? 'expression tag'        -8  290 
9 9FF1 ASN E 47  ? UNP P28472 ? ? 'expression tag'        -7  291 
9 9FF1 LEU E 48  ? UNP P28472 ? ? 'expression tag'        -6  292 
9 9FF1 TYR E 49  ? UNP P28472 ? ? 'expression tag'        -5  293 
9 9FF1 PHE E 50  ? UNP P28472 ? ? 'expression tag'        -4  294 
9 9FF1 GLN E 51  ? UNP P28472 ? ? 'expression tag'        -3  295 
9 9FF1 GLY E 52  ? UNP P28472 ? ? 'expression tag'        -2  296 
9 9FF1 THR E 53  ? UNP P28472 ? ? 'expression tag'        -1  297 
9 9FF1 GLY E 54  ? UNP P28472 ? ? 'expression tag'        0   298 
9 9FF1 SER E 362 ? UNP P28472 ? ? linker                  308 299 
9 9FF1 GLN E 363 ? UNP P28472 ? ? linker                  309 300 
9 9FF1 PRO E 364 ? UNP P28472 ? ? linker                  310 301 
9 9FF1 ALA E 365 ? UNP P28472 ? ? linker                  311 302 
9 9FF1 ARG E 366 ? UNP P28472 ? ? linker                  312 303 
9 9FF1 ALA E 367 ? UNP P28472 ? ? linker                  313 304 
9 9FF1 ALA E 368 ? UNP P28472 ? ? linker                  314 305 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN A 62  ? LYS A 75  ? ASN A 8   LYS A 21  1 ? 14 
HELX_P HELX_P2  AA2 LYS A 124 ? ALA A 127 ? LYS A 70  ALA A 73  5 ? 4  
HELX_P HELX_P3  AA3 ASP A 138 ? LEU A 145 ? ASP A 84  LEU A 91  5 ? 8  
HELX_P HELX_P4  AA4 GLY A 224 ? LYS A 227 ? GLY A 170 LYS A 173 5 ? 4  
HELX_P HELX_P5  AA5 GLY A 231 ? ILE A 235 ? GLY A 177 ILE A 181 5 ? 5  
HELX_P HELX_P6  AA6 ILE A 272 ? THR A 279 ? ILE A 218 THR A 225 1 ? 8  
HELX_P HELX_P7  AA7 THR A 279 ? SER A 293 ? THR A 225 SER A 239 1 ? 15 
HELX_P HELX_P8  AA8 PHE A 294 ? ILE A 296 ? PHE A 240 ILE A 242 5 ? 3  
HELX_P HELX_P9  AA9 ALA A 300 ? ILE A 318 ? ALA A 246 ILE A 264 1 ? 19 
HELX_P HELX_P10 AB1 ASN A 319 ? ARG A 323 ? ASN A 265 ARG A 269 5 ? 5  
HELX_P HELX_P11 AB2 LYS A 333 ? ILE A 359 ? LYS A 279 ILE A 305 1 ? 27 
HELX_P HELX_P12 AB3 GLN A 363 ? VAL A 394 ? GLN A 309 VAL A 447 1 ? 32 
HELX_P HELX_P13 AB4 ASN B 62  ? LEU B 74  ? ASN B 8   LEU B 20  1 ? 13 
HELX_P HELX_P14 AB5 LYS B 124 ? ALA B 127 ? LYS B 70  ALA B 73  5 ? 4  
HELX_P HELX_P15 AB6 ASP B 138 ? LEU B 145 ? ASP B 84  LEU B 91  5 ? 8  
HELX_P HELX_P16 AB7 ASP B 193 ? TYR B 197 ? ASP B 139 TYR B 143 5 ? 5  
HELX_P HELX_P17 AB8 GLY B 224 ? LYS B 227 ? GLY B 170 LYS B 173 5 ? 4  
HELX_P HELX_P18 AB9 ILE B 272 ? THR B 279 ? ILE B 218 THR B 225 1 ? 8  
HELX_P HELX_P19 AC1 THR B 279 ? VAL B 292 ? THR B 225 VAL B 238 1 ? 14 
HELX_P HELX_P20 AC2 SER B 293 ? TRP B 295 ? SER B 239 TRP B 241 5 ? 3  
HELX_P HELX_P21 AC3 ALA B 300 ? THR B 325 ? ALA B 246 THR B 271 1 ? 26 
HELX_P HELX_P22 AC4 LYS B 333 ? GLN B 363 ? LYS B 279 GLN B 309 1 ? 31 
HELX_P HELX_P23 AC5 GLN B 363 ? VAL B 394 ? GLN B 309 VAL B 447 1 ? 32 
HELX_P HELX_P24 AC6 ASN C 62  ? LYS C 75  ? ASN C 8   LYS C 21  1 ? 14 
HELX_P HELX_P25 AC7 LYS C 124 ? ALA C 127 ? LYS C 70  ALA C 73  5 ? 4  
HELX_P HELX_P26 AC8 ASP C 138 ? LEU C 145 ? ASP C 84  LEU C 91  5 ? 8  
HELX_P HELX_P27 AC9 GLY C 231 ? ILE C 235 ? GLY C 177 ILE C 181 5 ? 5  
HELX_P HELX_P28 AD1 ILE C 272 ? THR C 279 ? ILE C 218 THR C 225 1 ? 8  
HELX_P HELX_P29 AD2 THR C 279 ? VAL C 292 ? THR C 225 VAL C 238 1 ? 14 
HELX_P HELX_P30 AD3 SER C 293 ? ILE C 296 ? SER C 239 ILE C 242 5 ? 4  
HELX_P HELX_P31 AD4 ALA C 300 ? LEU C 322 ? ALA C 246 LEU C 268 1 ? 23 
HELX_P HELX_P32 AD5 ARG C 323 ? THR C 325 ? ARG C 269 THR C 271 5 ? 3  
HELX_P HELX_P33 AD6 LYS C 333 ? PHE C 361 ? LYS C 279 PHE C 307 1 ? 29 
HELX_P HELX_P34 AD7 GLN C 363 ? TYR C 393 ? GLN C 309 TYR C 446 1 ? 31 
HELX_P HELX_P35 AD8 ASN D 62  ? LEU D 74  ? ASN D 8   LEU D 20  1 ? 13 
HELX_P HELX_P36 AD9 LYS D 124 ? ALA D 127 ? LYS D 70  ALA D 73  5 ? 4  
HELX_P HELX_P37 AE1 ASP D 138 ? LEU D 145 ? ASP D 84  LEU D 91  5 ? 8  
HELX_P HELX_P38 AE2 ASP D 193 ? TYR D 197 ? ASP D 139 TYR D 143 5 ? 5  
HELX_P HELX_P39 AE3 GLY D 224 ? LYS D 227 ? GLY D 170 LYS D 173 5 ? 4  
HELX_P HELX_P40 AE4 ILE D 272 ? THR D 279 ? ILE D 218 THR D 225 1 ? 8  
HELX_P HELX_P41 AE5 THR D 279 ? ILE D 296 ? THR D 225 ILE D 242 1 ? 18 
HELX_P HELX_P42 AE6 ALA D 300 ? THR D 317 ? ALA D 246 THR D 263 1 ? 18 
HELX_P HELX_P43 AE7 ASN D 319 ? THR D 325 ? ASN D 265 THR D 271 1 ? 7  
HELX_P HELX_P44 AE8 LYS D 333 ? ILE D 359 ? LYS D 279 ILE D 305 1 ? 27 
HELX_P HELX_P45 AE9 GLN D 363 ? TYR D 393 ? GLN D 309 TYR D 446 1 ? 31 
HELX_P HELX_P46 AF1 ASN E 62  ? LYS E 75  ? ASN E 8   LYS E 21  1 ? 14 
HELX_P HELX_P47 AF2 LYS E 124 ? ALA E 127 ? LYS E 70  ALA E 73  5 ? 4  
HELX_P HELX_P48 AF3 ASP E 138 ? GLN E 144 ? ASP E 84  GLN E 90  5 ? 7  
HELX_P HELX_P49 AF4 GLY E 224 ? LYS E 227 ? GLY E 170 LYS E 173 5 ? 4  
HELX_P HELX_P50 AF5 GLY E 231 ? ILE E 235 ? GLY E 177 ILE E 181 5 ? 5  
HELX_P HELX_P51 AF6 ILE E 272 ? TYR E 280 ? ILE E 218 TYR E 226 1 ? 9  
HELX_P HELX_P52 AF7 TYR E 280 ? SER E 293 ? TYR E 226 SER E 239 1 ? 14 
HELX_P HELX_P53 AF8 ALA E 300 ? GLU E 324 ? ALA E 246 GLU E 270 1 ? 25 
HELX_P HELX_P54 AF9 LYS E 333 ? ILE E 359 ? LYS E 279 ILE E 305 1 ? 27 
HELX_P HELX_P55 AG1 GLN E 363 ? TYR E 393 ? GLN E 309 TYR E 446 1 ? 31 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 190 SG  ? ? ? 1_555 A CYS 204 SG ? ? A CYS 136 A CYS 150 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf2  disulf ?    ? B CYS 190 SG  ? ? ? 1_555 B CYS 204 SG ? ? B CYS 136 B CYS 150 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf3  disulf ?    ? C CYS 190 SG  ? ? ? 1_555 C CYS 204 SG ? ? C CYS 136 C CYS 150 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf4  disulf ?    ? D CYS 190 SG  ? ? ? 1_555 D CYS 204 SG ? ? D CYS 136 D CYS 150 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf5  disulf ?    ? E CYS 190 SG  ? ? ? 1_555 E CYS 204 SG ? ? E CYS 136 E CYS 150 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
covale1  covale one  ? A ASN 62  ND2 ? ? ? 1_555 P NAG .   C1 ? ? A ASN 8   A NAG 501 1_555 ? ? ? ? ? ? ? 1.436 ? N-Glycosylation 
covale2  covale one  ? A ASN 134 ND2 ? ? ? 1_555 G NAG .   C1 ? ? A ASN 80  F NAG 1   1_555 ? ? ? ? ? ? ? 1.437 ? N-Glycosylation 
covale3  covale one  ? A ASN 203 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 149 a NAG 1   1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale4  covale one  ? B ASN 62  ND2 ? ? ? 1_555 T NAG .   C1 ? ? B ASN 8   B NAG 502 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale5  covale one  ? B ASN 134 ND2 ? ? ? 1_555 I NAG .   C1 ? ? B ASN 80  G NAG 1   1_555 ? ? ? ? ? ? ? 1.438 ? N-Glycosylation 
covale6  covale one  ? B ASN 203 ND2 ? ? ? 1_555 H NAG .   C1 ? ? B ASN 149 b NAG 1   1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale7  covale one  ? C ASN 62  ND2 ? ? ? 1_555 U NAG .   C1 ? ? C ASN 8   C NAG 501 1_555 ? ? ? ? ? ? ? 1.436 ? N-Glycosylation 
covale8  covale one  ? C ASN 134 ND2 ? ? ? 1_555 K NAG .   C1 ? ? C ASN 80  H NAG 1   1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale9  covale one  ? C ASN 203 ND2 ? ? ? 1_555 J NAG .   C1 ? ? C ASN 149 c NAG 1   1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale10 covale one  ? D ASN 62  ND2 ? ? ? 1_555 W NAG .   C1 ? ? D ASN 8   D NAG 502 1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale11 covale one  ? D ASN 134 ND2 ? ? ? 1_555 M NAG .   C1 ? ? D ASN 80  I NAG 1   1_555 ? ? ? ? ? ? ? 1.436 ? N-Glycosylation 
covale12 covale one  ? D ASN 203 ND2 ? ? ? 1_555 L NAG .   C1 ? ? D ASN 149 d NAG 1   1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale13 covale one  ? E ASN 62  ND2 ? ? ? 1_555 X NAG .   C1 ? ? E ASN 8   E NAG 501 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale14 covale one  ? E ASN 134 ND2 ? ? ? 1_555 O NAG .   C1 ? ? E ASN 80  J NAG 1   1_555 ? ? ? ? ? ? ? 1.437 ? N-Glycosylation 
covale15 covale one  ? E ASN 203 ND2 ? ? ? 1_555 N NAG .   C1 ? ? E ASN 149 e NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale16 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? a NAG 1   a NAG 2   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale17 covale both ? F NAG .   O4  ? ? ? 1_555 F BMA .   C1 ? ? a NAG 2   a BMA 3   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale18 covale both ? F BMA .   O3  ? ? ? 1_555 F MAN .   C1 ? ? a BMA 3   a MAN 4   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale19 covale both ? F BMA .   O6  ? ? ? 1_555 F MAN .   C1 ? ? a BMA 3   a MAN 5   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale20 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale21 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? b NAG 1   b NAG 2   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale22 covale both ? H NAG .   O4  ? ? ? 1_555 H BMA .   C1 ? ? b NAG 2   b BMA 3   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale23 covale both ? H BMA .   O3  ? ? ? 1_555 H MAN .   C1 ? ? b BMA 3   b MAN 4   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale24 covale both ? H BMA .   O6  ? ? ? 1_555 H MAN .   C1 ? ? b BMA 3   b MAN 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale25 covale both ? I NAG .   O4  ? ? ? 1_555 I NAG .   C1 ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
covale26 covale both ? J NAG .   O4  ? ? ? 1_555 J NAG .   C1 ? ? c NAG 1   c NAG 2   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale27 covale both ? J NAG .   O4  ? ? ? 1_555 J BMA .   C1 ? ? c NAG 2   c BMA 3   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
covale28 covale both ? J BMA .   O3  ? ? ? 1_555 J MAN .   C1 ? ? c BMA 3   c MAN 4   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
covale29 covale both ? J BMA .   O6  ? ? ? 1_555 J MAN .   C1 ? ? c BMA 3   c MAN 5   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale30 covale both ? K NAG .   O4  ? ? ? 1_555 K NAG .   C1 ? ? H NAG 1   H NAG 2   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale31 covale both ? L NAG .   O4  ? ? ? 1_555 L NAG .   C1 ? ? d NAG 1   d NAG 2   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
covale32 covale both ? L NAG .   O4  ? ? ? 1_555 L BMA .   C1 ? ? d NAG 2   d BMA 3   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale33 covale both ? L BMA .   O3  ? ? ? 1_555 L MAN .   C1 ? ? d BMA 3   d MAN 4   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale34 covale both ? L BMA .   O6  ? ? ? 1_555 L MAN .   C1 ? ? d BMA 3   d MAN 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale35 covale both ? M NAG .   O4  ? ? ? 1_555 M NAG .   C1 ? ? I NAG 1   I NAG 2   1_555 ? ? ? ? ? ? ? 1.447 ? ?               
covale36 covale both ? N NAG .   O4  ? ? ? 1_555 N NAG .   C1 ? ? e NAG 1   e NAG 2   1_555 ? ? ? ? ? ? ? 1.437 ? ?               
covale37 covale both ? N NAG .   O4  ? ? ? 1_555 N BMA .   C1 ? ? e NAG 2   e BMA 3   1_555 ? ? ? ? ? ? ? 1.449 ? ?               
covale38 covale both ? N BMA .   O3  ? ? ? 1_555 N MAN .   C1 ? ? e BMA 3   e MAN 4   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale39 covale both ? N BMA .   O6  ? ? ? 1_555 N MAN .   C1 ? ? e BMA 3   e MAN 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale40 covale both ? O NAG .   O4  ? ? ? 1_555 O NAG .   C1 ? ? J NAG 1   J NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG F .   ? ASN A 203 ? NAG a 1   ? 1_555 ASN A 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG G .   ? ASN A 134 ? NAG F 1   ? 1_555 ASN A 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG H .   ? ASN B 203 ? NAG b 1   ? 1_555 ASN B 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG I .   ? ASN B 134 ? NAG G 1   ? 1_555 ASN B 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG J .   ? ASN C 203 ? NAG c 1   ? 1_555 ASN C 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG K .   ? ASN C 134 ? NAG H 1   ? 1_555 ASN C 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG L .   ? ASN D 203 ? NAG d 1   ? 1_555 ASN D 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG M .   ? ASN D 134 ? NAG I 1   ? 1_555 ASN D 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  NAG N .   ? ASN E 203 ? NAG e 1   ? 1_555 ASN E 149 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
10 NAG O .   ? ASN E 134 ? NAG J 1   ? 1_555 ASN E 80  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
11 NAG P .   ? ASN A 62  ? NAG A 501 ? 1_555 ASN A 8   ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
12 NAG T .   ? ASN B 62  ? NAG B 502 ? 1_555 ASN B 8   ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
13 NAG U .   ? ASN C 62  ? NAG C 501 ? 1_555 ASN C 8   ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
14 NAG W .   ? ASN D 62  ? NAG D 502 ? 1_555 ASN D 8   ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
15 NAG X .   ? ASN E 62  ? NAG E 501 ? 1_555 ASN E 8   ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
16 CYS A 190 ? CYS A 204 ? CYS A 136 ? 1_555 CYS A 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
17 CYS B 190 ? CYS B 204 ? CYS B 136 ? 1_555 CYS B 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
18 CYS C 190 ? CYS C 204 ? CYS C 136 ? 1_555 CYS C 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
19 CYS D 190 ? CYS D 204 ? CYS D 136 ? 1_555 CYS D 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
20 CYS E 190 ? CYS E 204 ? CYS E 136 ? 1_555 CYS E 150 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1  VAL 163 A . ? VAL 109 A THR 164 A ? THR 110 A 1 1.95  
2  TYR 197 A . ? TYR 143 A PRO 198 A ? PRO 144 A 1 1.83  
3  VAL 163 B . ? VAL 109 B THR 164 B ? THR 110 B 1 1.60  
4  TYR 197 B . ? TYR 143 B PRO 198 B ? PRO 144 B 1 0.61  
5  VAL 163 C . ? VAL 109 C THR 164 C ? THR 110 C 1 0.00  
6  TYR 197 C . ? TYR 143 C PRO 198 C ? PRO 144 C 1 3.40  
7  VAL 163 D . ? VAL 109 D THR 164 D ? THR 110 D 1 1.90  
8  TYR 197 D . ? TYR 143 D PRO 198 D ? PRO 144 D 1 -0.80 
9  VAL 163 E . ? VAL 109 E THR 164 E ? THR 110 E 1 -0.21 
10 TYR 197 E . ? TYR 143 E PRO 198 E ? PRO 144 E 1 0.77  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 4 ? 
AA3 ? 9 ? 
AA4 ? 4 ? 
AA5 ? 8 ? 
AA6 ? 4 ? 
AA7 ? 8 ? 
AA8 ? 4 ? 
AA9 ? 8 ? 
AB1 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 1 7 ? parallel      
AA1 1 8 ? parallel      
AA1 2 6 ? anti-parallel 
AA1 3 5 ? anti-parallel 
AA1 4 6 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 3 ? anti-parallel 
AA3 1 8 ? parallel      
AA3 1 9 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 7 ? anti-parallel 
AA3 4 6 ? anti-parallel 
AA3 5 7 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 1 7 ? parallel      
AA5 1 8 ? parallel      
AA5 2 6 ? anti-parallel 
AA5 3 5 ? anti-parallel 
AA5 4 6 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 1 7 ? parallel      
AA7 1 8 ? parallel      
AA7 2 6 ? anti-parallel 
AA7 3 5 ? anti-parallel 
AA7 4 6 ? anti-parallel 
AA7 5 6 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 1 7 ? parallel      
AA9 1 8 ? parallel      
AA9 2 6 ? anti-parallel 
AA9 3 5 ? anti-parallel 
AA9 4 6 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 90  ? SER A 105 ? VAL A 36  SER A 51  
AA1 2 ASP A 110 ? ARG A 122 ? ASP A 56  ARG A 68  
AA1 3 LEU A 135 ? LEU A 137 ? LEU A 81  LEU A 83  
AA1 4 PHE A 159 ? VAL A 160 ? PHE A 105 VAL A 106 
AA1 5 ARG A 168 ? LEU A 172 ? ARG A 114 LEU A 118 
AA1 6 THR A 177 ? ALA A 189 ? THR A 123 ALA A 135 
AA1 7 ILE A 218 ? TRP A 222 ? ILE A 164 TRP A 168 
AA1 8 VAL A 229 ? THR A 230 ? VAL A 175 THR A 176 
AA2 1 THR A 150 ? PHE A 152 ? THR A 96  PHE A 98  
AA2 2 GLU A 201 ? SER A 210 ? GLU A 147 SER A 156 
AA2 3 GLY A 257 ? ARG A 270 ? GLY A 203 ARG A 216 
AA2 4 PHE A 240 ? PHE A 254 ? PHE A 186 PHE A 200 
AA3 1 VAL B 90  ? SER B 100 ? VAL B 36  SER B 46  
AA3 2 VAL B 104 ? SER B 105 ? VAL B 50  SER B 51  
AA3 3 ASP B 110 ? ARG B 122 ? ASP B 56  ARG B 68  
AA3 4 LEU B 135 ? LEU B 137 ? LEU B 81  LEU B 83  
AA3 5 ASP B 155 ? VAL B 160 ? ASP B 101 VAL B 106 
AA3 6 ARG B 168 ? LEU B 172 ? ARG B 114 LEU B 118 
AA3 7 THR B 177 ? ALA B 189 ? THR B 123 ALA B 135 
AA3 8 ILE B 218 ? TRP B 222 ? ILE B 164 TRP B 168 
AA3 9 VAL B 229 ? THR B 230 ? VAL B 175 THR B 176 
AA4 1 THR B 150 ? PHE B 152 ? THR B 96  PHE B 98  
AA4 2 GLU B 201 ? SER B 210 ? GLU B 147 SER B 156 
AA4 3 GLY B 257 ? ARG B 270 ? GLY B 203 ARG B 216 
AA4 4 PHE B 240 ? PHE B 254 ? PHE B 186 PHE B 200 
AA5 1 VAL C 90  ? SER C 105 ? VAL C 36  SER C 51  
AA5 2 ASP C 110 ? ARG C 122 ? ASP C 56  ARG C 68  
AA5 3 LEU C 135 ? LEU C 137 ? LEU C 81  LEU C 83  
AA5 4 ASP C 155 ? VAL C 160 ? ASP C 101 VAL C 106 
AA5 5 ARG C 168 ? LEU C 172 ? ARG C 114 LEU C 118 
AA5 6 THR C 177 ? ALA C 189 ? THR C 123 ALA C 135 
AA5 7 ILE C 218 ? TRP C 222 ? ILE C 164 TRP C 168 
AA5 8 VAL C 229 ? THR C 230 ? VAL C 175 THR C 176 
AA6 1 THR C 150 ? PHE C 152 ? THR C 96  PHE C 98  
AA6 2 GLU C 201 ? SER C 210 ? GLU C 147 SER C 156 
AA6 3 GLY C 257 ? ARG C 270 ? GLY C 203 ARG C 216 
AA6 4 PHE C 240 ? PHE C 254 ? PHE C 186 PHE C 200 
AA7 1 VAL D 90  ? SER D 105 ? VAL D 36  SER D 51  
AA7 2 ASP D 110 ? ARG D 122 ? ASP D 56  ARG D 68  
AA7 3 LEU D 135 ? LEU D 137 ? LEU D 81  LEU D 83  
AA7 4 ASP D 155 ? VAL D 160 ? ASP D 101 VAL D 106 
AA7 5 ARG D 168 ? LEU D 172 ? ARG D 114 LEU D 118 
AA7 6 THR D 177 ? ALA D 189 ? THR D 123 ALA D 135 
AA7 7 ILE D 218 ? TRP D 222 ? ILE D 164 TRP D 168 
AA7 8 VAL D 229 ? THR D 230 ? VAL D 175 THR D 176 
AA8 1 THR D 150 ? PHE D 152 ? THR D 96  PHE D 98  
AA8 2 GLU D 201 ? SER D 210 ? GLU D 147 SER D 156 
AA8 3 GLY D 257 ? ARG D 270 ? GLY D 203 ARG D 216 
AA8 4 PHE D 240 ? PHE D 254 ? PHE D 186 PHE D 200 
AA9 1 VAL E 90  ? SER E 105 ? VAL E 36  SER E 51  
AA9 2 ASP E 110 ? ARG E 122 ? ASP E 56  ARG E 68  
AA9 3 LEU E 135 ? LEU E 137 ? LEU E 81  LEU E 83  
AA9 4 ASP E 155 ? VAL E 160 ? ASP E 101 VAL E 106 
AA9 5 ARG E 168 ? LEU E 172 ? ARG E 114 LEU E 118 
AA9 6 THR E 177 ? ALA E 189 ? THR E 123 ALA E 135 
AA9 7 ILE E 218 ? TRP E 222 ? ILE E 164 TRP E 168 
AA9 8 VAL E 229 ? THR E 230 ? VAL E 175 THR E 176 
AB1 1 THR E 150 ? PHE E 152 ? THR E 96  PHE E 98  
AB1 2 GLU E 201 ? SER E 210 ? GLU E 147 SER E 156 
AB1 3 GLY E 257 ? ARG E 270 ? GLY E 203 ARG E 216 
AB1 4 PHE E 240 ? PHE E 254 ? PHE E 186 PHE E 200 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ASN A 95  ? N ASN A 41  O GLN A 118 ? O GLN A 64  
AA1 1 7 N VAL A 92  ? N VAL A 38  O GLU A 219 ? O GLU A 165 
AA1 1 8 N ILE A 96  ? N ILE A 42  O THR A 230 ? O THR A 176 
AA1 2 6 N TRP A 121 ? N TRP A 67  O VAL A 178 ? O VAL A 124 
AA1 3 5 N LEU A 135 ? N LEU A 81  O LEU A 172 ? O LEU A 118 
AA1 4 6 N PHE A 159 ? N PHE A 105 O THR A 185 ? O THR A 131 
AA1 5 6 N ARG A 171 ? N ARG A 117 O LEU A 179 ? O LEU A 125 
AA2 1 2 N TYR A 151 ? N TYR A 97  O GLU A 209 ? O GLU A 155 
AA2 2 3 N CYS A 204 ? N CYS A 150 O PHE A 266 ? O PHE A 212 
AA2 3 4 O LYS A 269 ? O LYS A 215 N SER A 241 ? N SER A 187 
AA3 1 3 N ASN B 95  ? N ASN B 41  O GLN B 118 ? O GLN B 64  
AA3 1 8 N VAL B 92  ? N VAL B 38  O GLU B 219 ? O GLU B 165 
AA3 1 9 N ILE B 98  ? N ILE B 44  O THR B 230 ? O THR B 176 
AA3 2 3 N SER B 105 ? N SER B 51  O ASP B 110 ? O ASP B 56  
AA3 3 7 N LEU B 113 ? N LEU B 59  O THR B 186 ? O THR B 132 
AA3 4 6 N LEU B 135 ? N LEU B 81  O LEU B 172 ? O LEU B 118 
AA3 5 7 N LYS B 156 ? N LYS B 102 O THR B 187 ? O THR B 133 
AA3 6 7 N ARG B 171 ? N ARG B 117 O LEU B 179 ? O LEU B 125 
AA4 1 2 N TYR B 151 ? N TYR B 97  O GLU B 209 ? O GLU B 155 
AA4 2 3 N ILE B 208 ? N ILE B 154 O LEU B 262 ? O LEU B 208 
AA4 3 4 O TYR B 259 ? O TYR B 205 N VAL B 252 ? N VAL B 198 
AA5 1 2 N GLY C 93  ? N GLY C 39  O TYR C 120 ? O TYR C 66  
AA5 1 7 N VAL C 92  ? N VAL C 38  O GLU C 219 ? O GLU C 165 
AA5 1 8 N ILE C 98  ? N ILE C 44  O THR C 230 ? O THR C 176 
AA5 2 6 N GLN C 119 ? N GLN C 65  O TYR C 180 ? O TYR C 126 
AA5 3 5 N LEU C 135 ? N LEU C 81  O LEU C 172 ? O LEU C 118 
AA5 4 6 N LYS C 156 ? N LYS C 102 O THR C 187 ? O THR C 133 
AA5 5 6 N ARG C 171 ? N ARG C 117 O LEU C 179 ? O LEU C 125 
AA6 1 2 N TYR C 151 ? N TYR C 97  O GLU C 209 ? O GLU C 155 
AA6 2 3 N ILE C 208 ? N ILE C 154 O LEU C 262 ? O LEU C 208 
AA6 3 4 O GLY C 257 ? O GLY C 203 N PHE C 254 ? N PHE C 200 
AA7 1 2 N GLY D 93  ? N GLY D 39  O TYR D 120 ? O TYR D 66  
AA7 1 7 N VAL D 92  ? N VAL D 38  O GLU D 219 ? O GLU D 165 
AA7 1 8 N ILE D 98  ? N ILE D 44  O THR D 230 ? O THR D 176 
AA7 2 6 N TRP D 121 ? N TRP D 67  O VAL D 178 ? O VAL D 124 
AA7 3 5 N LEU D 135 ? N LEU D 81  O LEU D 172 ? O LEU D 118 
AA7 4 6 N PHE D 159 ? N PHE D 105 O THR D 185 ? O THR D 131 
AA7 5 6 N ARG D 171 ? N ARG D 117 O LEU D 179 ? O LEU D 125 
AA8 1 2 N TYR D 151 ? N TYR D 97  O GLU D 209 ? O GLU D 155 
AA8 2 3 N CYS D 204 ? N CYS D 150 O PHE D 266 ? O PHE D 212 
AA8 3 4 O TYR D 259 ? O TYR D 205 N VAL D 252 ? N VAL D 198 
AA9 1 2 N SER E 105 ? N SER E 51  O ASP E 110 ? O ASP E 56  
AA9 1 7 N VAL E 92  ? N VAL E 38  O GLU E 219 ? O GLU E 165 
AA9 1 8 N ILE E 96  ? N ILE E 42  O THR E 230 ? O THR E 176 
AA9 2 6 N GLN E 119 ? N GLN E 65  O TYR E 180 ? O TYR E 126 
AA9 3 5 N LEU E 135 ? N LEU E 81  O LEU E 172 ? O LEU E 118 
AA9 4 6 N PHE E 159 ? N PHE E 105 O THR E 185 ? O THR E 131 
AA9 5 6 N ARG E 171 ? N ARG E 117 O LEU E 179 ? O LEU E 125 
AB1 1 2 N TYR E 151 ? N TYR E 97  O GLU E 209 ? O GLU E 155 
AB1 2 3 N CYS E 204 ? N CYS E 150 O PHE E 266 ? O PHE E 212 
AB1 3 4 O GLY E 257 ? O GLY E 203 N PHE E 254 ? N PHE E 200 
# 
_pdbx_entry_details.entry_id                   9FF1 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 78  ? ? -85.26  49.10 
2  1 PRO A 276 ? ? -88.96  49.74 
3  1 PRO B 78  ? ? -82.50  49.48 
4  1 PRO C 78  ? ? -78.81  46.48 
5  1 LYS C 274 ? ? -90.18  58.79 
6  1 PRO D 78  ? ? -81.45  47.65 
7  1 ASN D 113 ? ? -69.96  86.51 
8  1 PRO D 144 ? ? -96.59  44.58 
9  1 THR D 202 ? ? -92.83  51.65 
10 1 THR D 263 ? ? -101.78 42.76 
11 1 ASN D 265 ? ? -99.21  31.22 
12 1 THR D 271 ? ? -95.26  31.43 
13 1 LYS D 274 ? ? -101.30 41.51 
14 1 PRO D 276 ? ? -80.04  47.66 
15 1 PRO E 78  ? ? -77.48  46.82 
16 1 LEU E 145 ? ? -96.31  34.72 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9FF1 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   'FSC at 0.5' 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   30 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      OTHER 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  7A5V 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                7A5V 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    9FF1 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.2 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               20000 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '137 mM NaCl, 2.7 mM KCl, 4.3 mM Na2HPO' 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric desensitised state' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_image_scans.entry_id                9FF1 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        4096 
_em_image_scans.dimension_width         4096 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9FF1 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1400 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           96000 
_em_imaging.calibrated_magnification        96000 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          'current: 30mA' 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9FF1 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   281 
_em_vitrification.instrument            'HOMEMADE PLUNGER' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9FF1 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9FF1 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -53 ? A MET 1   
2   1 Y 1 A ASP -52 ? A ASP 2   
3   1 Y 1 A GLU -51 ? A GLU 3   
4   1 Y 1 A LYS -50 ? A LYS 4   
5   1 Y 1 A THR -49 ? A THR 5   
6   1 Y 1 A THR -48 ? A THR 6   
7   1 Y 1 A GLY -47 ? A GLY 7   
8   1 Y 1 A TRP -46 ? A TRP 8   
9   1 Y 1 A ARG -45 ? A ARG 9   
10  1 Y 1 A GLY -44 ? A GLY 10  
11  1 Y 1 A GLY -43 ? A GLY 11  
12  1 Y 1 A HIS -42 ? A HIS 12  
13  1 Y 1 A VAL -41 ? A VAL 13  
14  1 Y 1 A VAL -40 ? A VAL 14  
15  1 Y 1 A GLU -39 ? A GLU 15  
16  1 Y 1 A GLY -38 ? A GLY 16  
17  1 Y 1 A LEU -37 ? A LEU 17  
18  1 Y 1 A ALA -36 ? A ALA 18  
19  1 Y 1 A GLY -35 ? A GLY 19  
20  1 Y 1 A GLU -34 ? A GLU 20  
21  1 Y 1 A LEU -33 ? A LEU 21  
22  1 Y 1 A GLU -32 ? A GLU 22  
23  1 Y 1 A GLN -31 ? A GLN 23  
24  1 Y 1 A LEU -30 ? A LEU 24  
25  1 Y 1 A ARG -29 ? A ARG 25  
26  1 Y 1 A ALA -28 ? A ALA 26  
27  1 Y 1 A ARG -27 ? A ARG 27  
28  1 Y 1 A LEU -26 ? A LEU 28  
29  1 Y 1 A GLU -25 ? A GLU 29  
30  1 Y 1 A HIS -24 ? A HIS 30  
31  1 Y 1 A HIS -23 ? A HIS 31  
32  1 Y 1 A PRO -22 ? A PRO 32  
33  1 Y 1 A GLN -21 ? A GLN 33  
34  1 Y 1 A GLY -20 ? A GLY 34  
35  1 Y 1 A GLN -19 ? A GLN 35  
36  1 Y 1 A ARG -18 ? A ARG 36  
37  1 Y 1 A GLU -17 ? A GLU 37  
38  1 Y 1 A PRO -16 ? A PRO 38  
39  1 Y 1 A ASP -15 ? A ASP 39  
40  1 Y 1 A TYR -14 ? A TYR 40  
41  1 Y 1 A ASP -13 ? A ASP 41  
42  1 Y 1 A ILE -12 ? A ILE 42  
43  1 Y 1 A PRO -11 ? A PRO 43  
44  1 Y 1 A THR -10 ? A THR 44  
45  1 Y 1 A THR -9  ? A THR 45  
46  1 Y 1 A GLU -8  ? A GLU 46  
47  1 Y 1 A ASN -7  ? A ASN 47  
48  1 Y 1 A LEU -6  ? A LEU 48  
49  1 Y 1 A TYR -5  ? A TYR 49  
50  1 Y 1 A PHE -4  ? A PHE 50  
51  1 Y 1 A GLN -3  ? A GLN 51  
52  1 Y 1 A GLY -2  ? A GLY 52  
53  1 Y 1 A THR -1  ? A THR 53  
54  1 Y 1 A GLY 0   ? A GLY 54  
55  1 Y 1 A GLN 1   ? A GLN 55  
56  1 Y 1 A SER 2   ? A SER 56  
57  1 Y 1 A VAL 3   ? A VAL 57  
58  1 Y 1 A ASN 448 ? A ASN 395 
59  1 Y 1 B MET -53 ? B MET 1   
60  1 Y 1 B ASP -52 ? B ASP 2   
61  1 Y 1 B GLU -51 ? B GLU 3   
62  1 Y 1 B LYS -50 ? B LYS 4   
63  1 Y 1 B THR -49 ? B THR 5   
64  1 Y 1 B THR -48 ? B THR 6   
65  1 Y 1 B GLY -47 ? B GLY 7   
66  1 Y 1 B TRP -46 ? B TRP 8   
67  1 Y 1 B ARG -45 ? B ARG 9   
68  1 Y 1 B GLY -44 ? B GLY 10  
69  1 Y 1 B GLY -43 ? B GLY 11  
70  1 Y 1 B HIS -42 ? B HIS 12  
71  1 Y 1 B VAL -41 ? B VAL 13  
72  1 Y 1 B VAL -40 ? B VAL 14  
73  1 Y 1 B GLU -39 ? B GLU 15  
74  1 Y 1 B GLY -38 ? B GLY 16  
75  1 Y 1 B LEU -37 ? B LEU 17  
76  1 Y 1 B ALA -36 ? B ALA 18  
77  1 Y 1 B GLY -35 ? B GLY 19  
78  1 Y 1 B GLU -34 ? B GLU 20  
79  1 Y 1 B LEU -33 ? B LEU 21  
80  1 Y 1 B GLU -32 ? B GLU 22  
81  1 Y 1 B GLN -31 ? B GLN 23  
82  1 Y 1 B LEU -30 ? B LEU 24  
83  1 Y 1 B ARG -29 ? B ARG 25  
84  1 Y 1 B ALA -28 ? B ALA 26  
85  1 Y 1 B ARG -27 ? B ARG 27  
86  1 Y 1 B LEU -26 ? B LEU 28  
87  1 Y 1 B GLU -25 ? B GLU 29  
88  1 Y 1 B HIS -24 ? B HIS 30  
89  1 Y 1 B HIS -23 ? B HIS 31  
90  1 Y 1 B PRO -22 ? B PRO 32  
91  1 Y 1 B GLN -21 ? B GLN 33  
92  1 Y 1 B GLY -20 ? B GLY 34  
93  1 Y 1 B GLN -19 ? B GLN 35  
94  1 Y 1 B ARG -18 ? B ARG 36  
95  1 Y 1 B GLU -17 ? B GLU 37  
96  1 Y 1 B PRO -16 ? B PRO 38  
97  1 Y 1 B ASP -15 ? B ASP 39  
98  1 Y 1 B TYR -14 ? B TYR 40  
99  1 Y 1 B ASP -13 ? B ASP 41  
100 1 Y 1 B ILE -12 ? B ILE 42  
101 1 Y 1 B PRO -11 ? B PRO 43  
102 1 Y 1 B THR -10 ? B THR 44  
103 1 Y 1 B THR -9  ? B THR 45  
104 1 Y 1 B GLU -8  ? B GLU 46  
105 1 Y 1 B ASN -7  ? B ASN 47  
106 1 Y 1 B LEU -6  ? B LEU 48  
107 1 Y 1 B TYR -5  ? B TYR 49  
108 1 Y 1 B PHE -4  ? B PHE 50  
109 1 Y 1 B GLN -3  ? B GLN 51  
110 1 Y 1 B GLY -2  ? B GLY 52  
111 1 Y 1 B THR -1  ? B THR 53  
112 1 Y 1 B GLY 0   ? B GLY 54  
113 1 Y 1 B GLN 1   ? B GLN 55  
114 1 Y 1 B SER 2   ? B SER 56  
115 1 Y 1 B VAL 3   ? B VAL 57  
116 1 Y 1 B ASN 448 ? B ASN 395 
117 1 Y 1 C MET -53 ? C MET 1   
118 1 Y 1 C ASP -52 ? C ASP 2   
119 1 Y 1 C GLU -51 ? C GLU 3   
120 1 Y 1 C LYS -50 ? C LYS 4   
121 1 Y 1 C THR -49 ? C THR 5   
122 1 Y 1 C THR -48 ? C THR 6   
123 1 Y 1 C GLY -47 ? C GLY 7   
124 1 Y 1 C TRP -46 ? C TRP 8   
125 1 Y 1 C ARG -45 ? C ARG 9   
126 1 Y 1 C GLY -44 ? C GLY 10  
127 1 Y 1 C GLY -43 ? C GLY 11  
128 1 Y 1 C HIS -42 ? C HIS 12  
129 1 Y 1 C VAL -41 ? C VAL 13  
130 1 Y 1 C VAL -40 ? C VAL 14  
131 1 Y 1 C GLU -39 ? C GLU 15  
132 1 Y 1 C GLY -38 ? C GLY 16  
133 1 Y 1 C LEU -37 ? C LEU 17  
134 1 Y 1 C ALA -36 ? C ALA 18  
135 1 Y 1 C GLY -35 ? C GLY 19  
136 1 Y 1 C GLU -34 ? C GLU 20  
137 1 Y 1 C LEU -33 ? C LEU 21  
138 1 Y 1 C GLU -32 ? C GLU 22  
139 1 Y 1 C GLN -31 ? C GLN 23  
140 1 Y 1 C LEU -30 ? C LEU 24  
141 1 Y 1 C ARG -29 ? C ARG 25  
142 1 Y 1 C ALA -28 ? C ALA 26  
143 1 Y 1 C ARG -27 ? C ARG 27  
144 1 Y 1 C LEU -26 ? C LEU 28  
145 1 Y 1 C GLU -25 ? C GLU 29  
146 1 Y 1 C HIS -24 ? C HIS 30  
147 1 Y 1 C HIS -23 ? C HIS 31  
148 1 Y 1 C PRO -22 ? C PRO 32  
149 1 Y 1 C GLN -21 ? C GLN 33  
150 1 Y 1 C GLY -20 ? C GLY 34  
151 1 Y 1 C GLN -19 ? C GLN 35  
152 1 Y 1 C ARG -18 ? C ARG 36  
153 1 Y 1 C GLU -17 ? C GLU 37  
154 1 Y 1 C PRO -16 ? C PRO 38  
155 1 Y 1 C ASP -15 ? C ASP 39  
156 1 Y 1 C TYR -14 ? C TYR 40  
157 1 Y 1 C ASP -13 ? C ASP 41  
158 1 Y 1 C ILE -12 ? C ILE 42  
159 1 Y 1 C PRO -11 ? C PRO 43  
160 1 Y 1 C THR -10 ? C THR 44  
161 1 Y 1 C THR -9  ? C THR 45  
162 1 Y 1 C GLU -8  ? C GLU 46  
163 1 Y 1 C ASN -7  ? C ASN 47  
164 1 Y 1 C LEU -6  ? C LEU 48  
165 1 Y 1 C TYR -5  ? C TYR 49  
166 1 Y 1 C PHE -4  ? C PHE 50  
167 1 Y 1 C GLN -3  ? C GLN 51  
168 1 Y 1 C GLY -2  ? C GLY 52  
169 1 Y 1 C THR -1  ? C THR 53  
170 1 Y 1 C GLY 0   ? C GLY 54  
171 1 Y 1 C GLN 1   ? C GLN 55  
172 1 Y 1 C SER 2   ? C SER 56  
173 1 Y 1 C VAL 3   ? C VAL 57  
174 1 Y 1 C ASN 448 ? C ASN 395 
175 1 Y 1 D MET -53 ? D MET 1   
176 1 Y 1 D ASP -52 ? D ASP 2   
177 1 Y 1 D GLU -51 ? D GLU 3   
178 1 Y 1 D LYS -50 ? D LYS 4   
179 1 Y 1 D THR -49 ? D THR 5   
180 1 Y 1 D THR -48 ? D THR 6   
181 1 Y 1 D GLY -47 ? D GLY 7   
182 1 Y 1 D TRP -46 ? D TRP 8   
183 1 Y 1 D ARG -45 ? D ARG 9   
184 1 Y 1 D GLY -44 ? D GLY 10  
185 1 Y 1 D GLY -43 ? D GLY 11  
186 1 Y 1 D HIS -42 ? D HIS 12  
187 1 Y 1 D VAL -41 ? D VAL 13  
188 1 Y 1 D VAL -40 ? D VAL 14  
189 1 Y 1 D GLU -39 ? D GLU 15  
190 1 Y 1 D GLY -38 ? D GLY 16  
191 1 Y 1 D LEU -37 ? D LEU 17  
192 1 Y 1 D ALA -36 ? D ALA 18  
193 1 Y 1 D GLY -35 ? D GLY 19  
194 1 Y 1 D GLU -34 ? D GLU 20  
195 1 Y 1 D LEU -33 ? D LEU 21  
196 1 Y 1 D GLU -32 ? D GLU 22  
197 1 Y 1 D GLN -31 ? D GLN 23  
198 1 Y 1 D LEU -30 ? D LEU 24  
199 1 Y 1 D ARG -29 ? D ARG 25  
200 1 Y 1 D ALA -28 ? D ALA 26  
201 1 Y 1 D ARG -27 ? D ARG 27  
202 1 Y 1 D LEU -26 ? D LEU 28  
203 1 Y 1 D GLU -25 ? D GLU 29  
204 1 Y 1 D HIS -24 ? D HIS 30  
205 1 Y 1 D HIS -23 ? D HIS 31  
206 1 Y 1 D PRO -22 ? D PRO 32  
207 1 Y 1 D GLN -21 ? D GLN 33  
208 1 Y 1 D GLY -20 ? D GLY 34  
209 1 Y 1 D GLN -19 ? D GLN 35  
210 1 Y 1 D ARG -18 ? D ARG 36  
211 1 Y 1 D GLU -17 ? D GLU 37  
212 1 Y 1 D PRO -16 ? D PRO 38  
213 1 Y 1 D ASP -15 ? D ASP 39  
214 1 Y 1 D TYR -14 ? D TYR 40  
215 1 Y 1 D ASP -13 ? D ASP 41  
216 1 Y 1 D ILE -12 ? D ILE 42  
217 1 Y 1 D PRO -11 ? D PRO 43  
218 1 Y 1 D THR -10 ? D THR 44  
219 1 Y 1 D THR -9  ? D THR 45  
220 1 Y 1 D GLU -8  ? D GLU 46  
221 1 Y 1 D ASN -7  ? D ASN 47  
222 1 Y 1 D LEU -6  ? D LEU 48  
223 1 Y 1 D TYR -5  ? D TYR 49  
224 1 Y 1 D PHE -4  ? D PHE 50  
225 1 Y 1 D GLN -3  ? D GLN 51  
226 1 Y 1 D GLY -2  ? D GLY 52  
227 1 Y 1 D THR -1  ? D THR 53  
228 1 Y 1 D GLY 0   ? D GLY 54  
229 1 Y 1 D GLN 1   ? D GLN 55  
230 1 Y 1 D SER 2   ? D SER 56  
231 1 Y 1 D VAL 3   ? D VAL 57  
232 1 Y 1 D ASN 448 ? D ASN 395 
233 1 Y 1 E MET -53 ? E MET 1   
234 1 Y 1 E ASP -52 ? E ASP 2   
235 1 Y 1 E GLU -51 ? E GLU 3   
236 1 Y 1 E LYS -50 ? E LYS 4   
237 1 Y 1 E THR -49 ? E THR 5   
238 1 Y 1 E THR -48 ? E THR 6   
239 1 Y 1 E GLY -47 ? E GLY 7   
240 1 Y 1 E TRP -46 ? E TRP 8   
241 1 Y 1 E ARG -45 ? E ARG 9   
242 1 Y 1 E GLY -44 ? E GLY 10  
243 1 Y 1 E GLY -43 ? E GLY 11  
244 1 Y 1 E HIS -42 ? E HIS 12  
245 1 Y 1 E VAL -41 ? E VAL 13  
246 1 Y 1 E VAL -40 ? E VAL 14  
247 1 Y 1 E GLU -39 ? E GLU 15  
248 1 Y 1 E GLY -38 ? E GLY 16  
249 1 Y 1 E LEU -37 ? E LEU 17  
250 1 Y 1 E ALA -36 ? E ALA 18  
251 1 Y 1 E GLY -35 ? E GLY 19  
252 1 Y 1 E GLU -34 ? E GLU 20  
253 1 Y 1 E LEU -33 ? E LEU 21  
254 1 Y 1 E GLU -32 ? E GLU 22  
255 1 Y 1 E GLN -31 ? E GLN 23  
256 1 Y 1 E LEU -30 ? E LEU 24  
257 1 Y 1 E ARG -29 ? E ARG 25  
258 1 Y 1 E ALA -28 ? E ALA 26  
259 1 Y 1 E ARG -27 ? E ARG 27  
260 1 Y 1 E LEU -26 ? E LEU 28  
261 1 Y 1 E GLU -25 ? E GLU 29  
262 1 Y 1 E HIS -24 ? E HIS 30  
263 1 Y 1 E HIS -23 ? E HIS 31  
264 1 Y 1 E PRO -22 ? E PRO 32  
265 1 Y 1 E GLN -21 ? E GLN 33  
266 1 Y 1 E GLY -20 ? E GLY 34  
267 1 Y 1 E GLN -19 ? E GLN 35  
268 1 Y 1 E ARG -18 ? E ARG 36  
269 1 Y 1 E GLU -17 ? E GLU 37  
270 1 Y 1 E PRO -16 ? E PRO 38  
271 1 Y 1 E ASP -15 ? E ASP 39  
272 1 Y 1 E TYR -14 ? E TYR 40  
273 1 Y 1 E ASP -13 ? E ASP 41  
274 1 Y 1 E ILE -12 ? E ILE 42  
275 1 Y 1 E PRO -11 ? E PRO 43  
276 1 Y 1 E THR -10 ? E THR 44  
277 1 Y 1 E THR -9  ? E THR 45  
278 1 Y 1 E GLU -8  ? E GLU 46  
279 1 Y 1 E ASN -7  ? E ASN 47  
280 1 Y 1 E LEU -6  ? E LEU 48  
281 1 Y 1 E TYR -5  ? E TYR 49  
282 1 Y 1 E PHE -4  ? E PHE 50  
283 1 Y 1 E GLN -3  ? E GLN 51  
284 1 Y 1 E GLY -2  ? E GLY 52  
285 1 Y 1 E THR -1  ? E THR 53  
286 1 Y 1 E GLY 0   ? E GLY 54  
287 1 Y 1 E GLN 1   ? E GLN 55  
288 1 Y 1 E SER 2   ? E SER 56  
289 1 Y 1 E VAL 3   ? E VAL 57  
290 1 Y 1 E ASN 448 ? E ASN 395 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GLN N    N N N 112 
GLN CA   C N S 113 
GLN C    C N N 114 
GLN O    O N N 115 
GLN CB   C N N 116 
GLN CG   C N N 117 
GLN CD   C N N 118 
GLN OE1  O N N 119 
GLN NE2  N N N 120 
GLN OXT  O N N 121 
GLN H    H N N 122 
GLN H2   H N N 123 
GLN HA   H N N 124 
GLN HB2  H N N 125 
GLN HB3  H N N 126 
GLN HG2  H N N 127 
GLN HG3  H N N 128 
GLN HE21 H N N 129 
GLN HE22 H N N 130 
GLN HXT  H N N 131 
GLU N    N N N 132 
GLU CA   C N S 133 
GLU C    C N N 134 
GLU O    O N N 135 
GLU CB   C N N 136 
GLU CG   C N N 137 
GLU CD   C N N 138 
GLU OE1  O N N 139 
GLU OE2  O N N 140 
GLU OXT  O N N 141 
GLU H    H N N 142 
GLU H2   H N N 143 
GLU HA   H N N 144 
GLU HB2  H N N 145 
GLU HB3  H N N 146 
GLU HG2  H N N 147 
GLU HG3  H N N 148 
GLU HE2  H N N 149 
GLU HXT  H N N 150 
GLY N    N N N 151 
GLY CA   C N N 152 
GLY C    C N N 153 
GLY O    O N N 154 
GLY OXT  O N N 155 
GLY H    H N N 156 
GLY H2   H N N 157 
GLY HA2  H N N 158 
GLY HA3  H N N 159 
GLY HXT  H N N 160 
HIS N    N N N 161 
HIS CA   C N S 162 
HIS C    C N N 163 
HIS O    O N N 164 
HIS CB   C N N 165 
HIS CG   C Y N 166 
HIS ND1  N Y N 167 
HIS CD2  C Y N 168 
HIS CE1  C Y N 169 
HIS NE2  N Y N 170 
HIS OXT  O N N 171 
HIS H    H N N 172 
HIS H2   H N N 173 
HIS HA   H N N 174 
HIS HB2  H N N 175 
HIS HB3  H N N 176 
HIS HD1  H N N 177 
HIS HD2  H N N 178 
HIS HE1  H N N 179 
HIS HE2  H N N 180 
HIS HXT  H N N 181 
HSM N    N N N 182 
HSM CA   C N N 183 
HSM CB   C N N 184 
HSM CG   C Y N 185 
HSM ND1  N Y N 186 
HSM CD2  C Y N 187 
HSM CE1  C Y N 188 
HSM NE2  N Y N 189 
HSM H1   H N N 190 
HSM H2   H N N 191 
HSM HA1  H N N 192 
HSM HA2  H N N 193 
HSM HB1  H N N 194 
HSM HB2  H N N 195 
HSM HD2  H N N 196 
HSM HE1  H N N 197 
HSM HE2  H N N 198 
ILE N    N N N 199 
ILE CA   C N S 200 
ILE C    C N N 201 
ILE O    O N N 202 
ILE CB   C N S 203 
ILE CG1  C N N 204 
ILE CG2  C N N 205 
ILE CD1  C N N 206 
ILE OXT  O N N 207 
ILE H    H N N 208 
ILE H2   H N N 209 
ILE HA   H N N 210 
ILE HB   H N N 211 
ILE HG12 H N N 212 
ILE HG13 H N N 213 
ILE HG21 H N N 214 
ILE HG22 H N N 215 
ILE HG23 H N N 216 
ILE HD11 H N N 217 
ILE HD12 H N N 218 
ILE HD13 H N N 219 
ILE HXT  H N N 220 
LEU N    N N N 221 
LEU CA   C N S 222 
LEU C    C N N 223 
LEU O    O N N 224 
LEU CB   C N N 225 
LEU CG   C N N 226 
LEU CD1  C N N 227 
LEU CD2  C N N 228 
LEU OXT  O N N 229 
LEU H    H N N 230 
LEU H2   H N N 231 
LEU HA   H N N 232 
LEU HB2  H N N 233 
LEU HB3  H N N 234 
LEU HG   H N N 235 
LEU HD11 H N N 236 
LEU HD12 H N N 237 
LEU HD13 H N N 238 
LEU HD21 H N N 239 
LEU HD22 H N N 240 
LEU HD23 H N N 241 
LEU HXT  H N N 242 
LYS N    N N N 243 
LYS CA   C N S 244 
LYS C    C N N 245 
LYS O    O N N 246 
LYS CB   C N N 247 
LYS CG   C N N 248 
LYS CD   C N N 249 
LYS CE   C N N 250 
LYS NZ   N N N 251 
LYS OXT  O N N 252 
LYS H    H N N 253 
LYS H2   H N N 254 
LYS HA   H N N 255 
LYS HB2  H N N 256 
LYS HB3  H N N 257 
LYS HG2  H N N 258 
LYS HG3  H N N 259 
LYS HD2  H N N 260 
LYS HD3  H N N 261 
LYS HE2  H N N 262 
LYS HE3  H N N 263 
LYS HZ1  H N N 264 
LYS HZ2  H N N 265 
LYS HZ3  H N N 266 
LYS HXT  H N N 267 
MAN C1   C N S 268 
MAN C2   C N S 269 
MAN C3   C N S 270 
MAN C4   C N S 271 
MAN C5   C N R 272 
MAN C6   C N N 273 
MAN O1   O N N 274 
MAN O2   O N N 275 
MAN O3   O N N 276 
MAN O4   O N N 277 
MAN O5   O N N 278 
MAN O6   O N N 279 
MAN H1   H N N 280 
MAN H2   H N N 281 
MAN H3   H N N 282 
MAN H4   H N N 283 
MAN H5   H N N 284 
MAN H61  H N N 285 
MAN H62  H N N 286 
MAN HO1  H N N 287 
MAN HO2  H N N 288 
MAN HO3  H N N 289 
MAN HO4  H N N 290 
MAN HO6  H N N 291 
MET N    N N N 292 
MET CA   C N S 293 
MET C    C N N 294 
MET O    O N N 295 
MET CB   C N N 296 
MET CG   C N N 297 
MET SD   S N N 298 
MET CE   C N N 299 
MET OXT  O N N 300 
MET H    H N N 301 
MET H2   H N N 302 
MET HA   H N N 303 
MET HB2  H N N 304 
MET HB3  H N N 305 
MET HG2  H N N 306 
MET HG3  H N N 307 
MET HE1  H N N 308 
MET HE2  H N N 309 
MET HE3  H N N 310 
MET HXT  H N N 311 
NAG C1   C N R 312 
NAG C2   C N R 313 
NAG C3   C N R 314 
NAG C4   C N S 315 
NAG C5   C N R 316 
NAG C6   C N N 317 
NAG C7   C N N 318 
NAG C8   C N N 319 
NAG N2   N N N 320 
NAG O1   O N N 321 
NAG O3   O N N 322 
NAG O4   O N N 323 
NAG O5   O N N 324 
NAG O6   O N N 325 
NAG O7   O N N 326 
NAG H1   H N N 327 
NAG H2   H N N 328 
NAG H3   H N N 329 
NAG H4   H N N 330 
NAG H5   H N N 331 
NAG H61  H N N 332 
NAG H62  H N N 333 
NAG H81  H N N 334 
NAG H82  H N N 335 
NAG H83  H N N 336 
NAG HN2  H N N 337 
NAG HO1  H N N 338 
NAG HO3  H N N 339 
NAG HO4  H N N 340 
NAG HO6  H N N 341 
PHE N    N N N 342 
PHE CA   C N S 343 
PHE C    C N N 344 
PHE O    O N N 345 
PHE CB   C N N 346 
PHE CG   C Y N 347 
PHE CD1  C Y N 348 
PHE CD2  C Y N 349 
PHE CE1  C Y N 350 
PHE CE2  C Y N 351 
PHE CZ   C Y N 352 
PHE OXT  O N N 353 
PHE H    H N N 354 
PHE H2   H N N 355 
PHE HA   H N N 356 
PHE HB2  H N N 357 
PHE HB3  H N N 358 
PHE HD1  H N N 359 
PHE HD2  H N N 360 
PHE HE1  H N N 361 
PHE HE2  H N N 362 
PHE HZ   H N N 363 
PHE HXT  H N N 364 
PRO N    N N N 365 
PRO CA   C N S 366 
PRO C    C N N 367 
PRO O    O N N 368 
PRO CB   C N N 369 
PRO CG   C N N 370 
PRO CD   C N N 371 
PRO OXT  O N N 372 
PRO H    H N N 373 
PRO HA   H N N 374 
PRO HB2  H N N 375 
PRO HB3  H N N 376 
PRO HG2  H N N 377 
PRO HG3  H N N 378 
PRO HD2  H N N 379 
PRO HD3  H N N 380 
PRO HXT  H N N 381 
SER N    N N N 382 
SER CA   C N S 383 
SER C    C N N 384 
SER O    O N N 385 
SER CB   C N N 386 
SER OG   O N N 387 
SER OXT  O N N 388 
SER H    H N N 389 
SER H2   H N N 390 
SER HA   H N N 391 
SER HB2  H N N 392 
SER HB3  H N N 393 
SER HG   H N N 394 
SER HXT  H N N 395 
THR N    N N N 396 
THR CA   C N S 397 
THR C    C N N 398 
THR O    O N N 399 
THR CB   C N R 400 
THR OG1  O N N 401 
THR CG2  C N N 402 
THR OXT  O N N 403 
THR H    H N N 404 
THR H2   H N N 405 
THR HA   H N N 406 
THR HB   H N N 407 
THR HG1  H N N 408 
THR HG21 H N N 409 
THR HG22 H N N 410 
THR HG23 H N N 411 
THR HXT  H N N 412 
TRP N    N N N 413 
TRP CA   C N S 414 
TRP C    C N N 415 
TRP O    O N N 416 
TRP CB   C N N 417 
TRP CG   C Y N 418 
TRP CD1  C Y N 419 
TRP CD2  C Y N 420 
TRP NE1  N Y N 421 
TRP CE2  C Y N 422 
TRP CE3  C Y N 423 
TRP CZ2  C Y N 424 
TRP CZ3  C Y N 425 
TRP CH2  C Y N 426 
TRP OXT  O N N 427 
TRP H    H N N 428 
TRP H2   H N N 429 
TRP HA   H N N 430 
TRP HB2  H N N 431 
TRP HB3  H N N 432 
TRP HD1  H N N 433 
TRP HE1  H N N 434 
TRP HE3  H N N 435 
TRP HZ2  H N N 436 
TRP HZ3  H N N 437 
TRP HH2  H N N 438 
TRP HXT  H N N 439 
TYR N    N N N 440 
TYR CA   C N S 441 
TYR C    C N N 442 
TYR O    O N N 443 
TYR CB   C N N 444 
TYR CG   C Y N 445 
TYR CD1  C Y N 446 
TYR CD2  C Y N 447 
TYR CE1  C Y N 448 
TYR CE2  C Y N 449 
TYR CZ   C Y N 450 
TYR OH   O N N 451 
TYR OXT  O N N 452 
TYR H    H N N 453 
TYR H2   H N N 454 
TYR HA   H N N 455 
TYR HB2  H N N 456 
TYR HB3  H N N 457 
TYR HD1  H N N 458 
TYR HD2  H N N 459 
TYR HE1  H N N 460 
TYR HE2  H N N 461 
TYR HH   H N N 462 
TYR HXT  H N N 463 
VAL N    N N N 464 
VAL CA   C N S 465 
VAL C    C N N 466 
VAL O    O N N 467 
VAL CB   C N N 468 
VAL CG1  C N N 469 
VAL CG2  C N N 470 
VAL OXT  O N N 471 
VAL H    H N N 472 
VAL H2   H N N 473 
VAL HA   H N N 474 
VAL HB   H N N 475 
VAL HG11 H N N 476 
VAL HG12 H N N 477 
VAL HG13 H N N 478 
VAL HG21 H N N 479 
VAL HG22 H N N 480 
VAL HG23 H N N 481 
VAL HXT  H N N 482 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GLN N   CA   sing N N 107 
GLN N   H    sing N N 108 
GLN N   H2   sing N N 109 
GLN CA  C    sing N N 110 
GLN CA  CB   sing N N 111 
GLN CA  HA   sing N N 112 
GLN C   O    doub N N 113 
GLN C   OXT  sing N N 114 
GLN CB  CG   sing N N 115 
GLN CB  HB2  sing N N 116 
GLN CB  HB3  sing N N 117 
GLN CG  CD   sing N N 118 
GLN CG  HG2  sing N N 119 
GLN CG  HG3  sing N N 120 
GLN CD  OE1  doub N N 121 
GLN CD  NE2  sing N N 122 
GLN NE2 HE21 sing N N 123 
GLN NE2 HE22 sing N N 124 
GLN OXT HXT  sing N N 125 
GLU N   CA   sing N N 126 
GLU N   H    sing N N 127 
GLU N   H2   sing N N 128 
GLU CA  C    sing N N 129 
GLU CA  CB   sing N N 130 
GLU CA  HA   sing N N 131 
GLU C   O    doub N N 132 
GLU C   OXT  sing N N 133 
GLU CB  CG   sing N N 134 
GLU CB  HB2  sing N N 135 
GLU CB  HB3  sing N N 136 
GLU CG  CD   sing N N 137 
GLU CG  HG2  sing N N 138 
GLU CG  HG3  sing N N 139 
GLU CD  OE1  doub N N 140 
GLU CD  OE2  sing N N 141 
GLU OE2 HE2  sing N N 142 
GLU OXT HXT  sing N N 143 
GLY N   CA   sing N N 144 
GLY N   H    sing N N 145 
GLY N   H2   sing N N 146 
GLY CA  C    sing N N 147 
GLY CA  HA2  sing N N 148 
GLY CA  HA3  sing N N 149 
GLY C   O    doub N N 150 
GLY C   OXT  sing N N 151 
GLY OXT HXT  sing N N 152 
HIS N   CA   sing N N 153 
HIS N   H    sing N N 154 
HIS N   H2   sing N N 155 
HIS CA  C    sing N N 156 
HIS CA  CB   sing N N 157 
HIS CA  HA   sing N N 158 
HIS C   O    doub N N 159 
HIS C   OXT  sing N N 160 
HIS CB  CG   sing N N 161 
HIS CB  HB2  sing N N 162 
HIS CB  HB3  sing N N 163 
HIS CG  ND1  sing Y N 164 
HIS CG  CD2  doub Y N 165 
HIS ND1 CE1  doub Y N 166 
HIS ND1 HD1  sing N N 167 
HIS CD2 NE2  sing Y N 168 
HIS CD2 HD2  sing N N 169 
HIS CE1 NE2  sing Y N 170 
HIS CE1 HE1  sing N N 171 
HIS NE2 HE2  sing N N 172 
HIS OXT HXT  sing N N 173 
HSM N   CA   sing N N 174 
HSM N   H1   sing N N 175 
HSM N   H2   sing N N 176 
HSM CA  CB   sing N N 177 
HSM CA  HA1  sing N N 178 
HSM CA  HA2  sing N N 179 
HSM CB  CG   sing N N 180 
HSM CB  HB1  sing N N 181 
HSM CB  HB2  sing N N 182 
HSM CG  ND1  sing Y N 183 
HSM CG  CD2  doub Y N 184 
HSM ND1 CE1  doub Y N 185 
HSM CD2 NE2  sing Y N 186 
HSM CD2 HD2  sing N N 187 
HSM CE1 NE2  sing Y N 188 
HSM CE1 HE1  sing N N 189 
HSM NE2 HE2  sing N N 190 
ILE N   CA   sing N N 191 
ILE N   H    sing N N 192 
ILE N   H2   sing N N 193 
ILE CA  C    sing N N 194 
ILE CA  CB   sing N N 195 
ILE CA  HA   sing N N 196 
ILE C   O    doub N N 197 
ILE C   OXT  sing N N 198 
ILE CB  CG1  sing N N 199 
ILE CB  CG2  sing N N 200 
ILE CB  HB   sing N N 201 
ILE CG1 CD1  sing N N 202 
ILE CG1 HG12 sing N N 203 
ILE CG1 HG13 sing N N 204 
ILE CG2 HG21 sing N N 205 
ILE CG2 HG22 sing N N 206 
ILE CG2 HG23 sing N N 207 
ILE CD1 HD11 sing N N 208 
ILE CD1 HD12 sing N N 209 
ILE CD1 HD13 sing N N 210 
ILE OXT HXT  sing N N 211 
LEU N   CA   sing N N 212 
LEU N   H    sing N N 213 
LEU N   H2   sing N N 214 
LEU CA  C    sing N N 215 
LEU CA  CB   sing N N 216 
LEU CA  HA   sing N N 217 
LEU C   O    doub N N 218 
LEU C   OXT  sing N N 219 
LEU CB  CG   sing N N 220 
LEU CB  HB2  sing N N 221 
LEU CB  HB3  sing N N 222 
LEU CG  CD1  sing N N 223 
LEU CG  CD2  sing N N 224 
LEU CG  HG   sing N N 225 
LEU CD1 HD11 sing N N 226 
LEU CD1 HD12 sing N N 227 
LEU CD1 HD13 sing N N 228 
LEU CD2 HD21 sing N N 229 
LEU CD2 HD22 sing N N 230 
LEU CD2 HD23 sing N N 231 
LEU OXT HXT  sing N N 232 
LYS N   CA   sing N N 233 
LYS N   H    sing N N 234 
LYS N   H2   sing N N 235 
LYS CA  C    sing N N 236 
LYS CA  CB   sing N N 237 
LYS CA  HA   sing N N 238 
LYS C   O    doub N N 239 
LYS C   OXT  sing N N 240 
LYS CB  CG   sing N N 241 
LYS CB  HB2  sing N N 242 
LYS CB  HB3  sing N N 243 
LYS CG  CD   sing N N 244 
LYS CG  HG2  sing N N 245 
LYS CG  HG3  sing N N 246 
LYS CD  CE   sing N N 247 
LYS CD  HD2  sing N N 248 
LYS CD  HD3  sing N N 249 
LYS CE  NZ   sing N N 250 
LYS CE  HE2  sing N N 251 
LYS CE  HE3  sing N N 252 
LYS NZ  HZ1  sing N N 253 
LYS NZ  HZ2  sing N N 254 
LYS NZ  HZ3  sing N N 255 
LYS OXT HXT  sing N N 256 
MAN C1  C2   sing N N 257 
MAN C1  O1   sing N N 258 
MAN C1  O5   sing N N 259 
MAN C1  H1   sing N N 260 
MAN C2  C3   sing N N 261 
MAN C2  O2   sing N N 262 
MAN C2  H2   sing N N 263 
MAN C3  C4   sing N N 264 
MAN C3  O3   sing N N 265 
MAN C3  H3   sing N N 266 
MAN C4  C5   sing N N 267 
MAN C4  O4   sing N N 268 
MAN C4  H4   sing N N 269 
MAN C5  C6   sing N N 270 
MAN C5  O5   sing N N 271 
MAN C5  H5   sing N N 272 
MAN C6  O6   sing N N 273 
MAN C6  H61  sing N N 274 
MAN C6  H62  sing N N 275 
MAN O1  HO1  sing N N 276 
MAN O2  HO2  sing N N 277 
MAN O3  HO3  sing N N 278 
MAN O4  HO4  sing N N 279 
MAN O6  HO6  sing N N 280 
MET N   CA   sing N N 281 
MET N   H    sing N N 282 
MET N   H2   sing N N 283 
MET CA  C    sing N N 284 
MET CA  CB   sing N N 285 
MET CA  HA   sing N N 286 
MET C   O    doub N N 287 
MET C   OXT  sing N N 288 
MET CB  CG   sing N N 289 
MET CB  HB2  sing N N 290 
MET CB  HB3  sing N N 291 
MET CG  SD   sing N N 292 
MET CG  HG2  sing N N 293 
MET CG  HG3  sing N N 294 
MET SD  CE   sing N N 295 
MET CE  HE1  sing N N 296 
MET CE  HE2  sing N N 297 
MET CE  HE3  sing N N 298 
MET OXT HXT  sing N N 299 
NAG C1  C2   sing N N 300 
NAG C1  O1   sing N N 301 
NAG C1  O5   sing N N 302 
NAG C1  H1   sing N N 303 
NAG C2  C3   sing N N 304 
NAG C2  N2   sing N N 305 
NAG C2  H2   sing N N 306 
NAG C3  C4   sing N N 307 
NAG C3  O3   sing N N 308 
NAG C3  H3   sing N N 309 
NAG C4  C5   sing N N 310 
NAG C4  O4   sing N N 311 
NAG C4  H4   sing N N 312 
NAG C5  C6   sing N N 313 
NAG C5  O5   sing N N 314 
NAG C5  H5   sing N N 315 
NAG C6  O6   sing N N 316 
NAG C6  H61  sing N N 317 
NAG C6  H62  sing N N 318 
NAG C7  C8   sing N N 319 
NAG C7  N2   sing N N 320 
NAG C7  O7   doub N N 321 
NAG C8  H81  sing N N 322 
NAG C8  H82  sing N N 323 
NAG C8  H83  sing N N 324 
NAG N2  HN2  sing N N 325 
NAG O1  HO1  sing N N 326 
NAG O3  HO3  sing N N 327 
NAG O4  HO4  sing N N 328 
NAG O6  HO6  sing N N 329 
PHE N   CA   sing N N 330 
PHE N   H    sing N N 331 
PHE N   H2   sing N N 332 
PHE CA  C    sing N N 333 
PHE CA  CB   sing N N 334 
PHE CA  HA   sing N N 335 
PHE C   O    doub N N 336 
PHE C   OXT  sing N N 337 
PHE CB  CG   sing N N 338 
PHE CB  HB2  sing N N 339 
PHE CB  HB3  sing N N 340 
PHE CG  CD1  doub Y N 341 
PHE CG  CD2  sing Y N 342 
PHE CD1 CE1  sing Y N 343 
PHE CD1 HD1  sing N N 344 
PHE CD2 CE2  doub Y N 345 
PHE CD2 HD2  sing N N 346 
PHE CE1 CZ   doub Y N 347 
PHE CE1 HE1  sing N N 348 
PHE CE2 CZ   sing Y N 349 
PHE CE2 HE2  sing N N 350 
PHE CZ  HZ   sing N N 351 
PHE OXT HXT  sing N N 352 
PRO N   CA   sing N N 353 
PRO N   CD   sing N N 354 
PRO N   H    sing N N 355 
PRO CA  C    sing N N 356 
PRO CA  CB   sing N N 357 
PRO CA  HA   sing N N 358 
PRO C   O    doub N N 359 
PRO C   OXT  sing N N 360 
PRO CB  CG   sing N N 361 
PRO CB  HB2  sing N N 362 
PRO CB  HB3  sing N N 363 
PRO CG  CD   sing N N 364 
PRO CG  HG2  sing N N 365 
PRO CG  HG3  sing N N 366 
PRO CD  HD2  sing N N 367 
PRO CD  HD3  sing N N 368 
PRO OXT HXT  sing N N 369 
SER N   CA   sing N N 370 
SER N   H    sing N N 371 
SER N   H2   sing N N 372 
SER CA  C    sing N N 373 
SER CA  CB   sing N N 374 
SER CA  HA   sing N N 375 
SER C   O    doub N N 376 
SER C   OXT  sing N N 377 
SER CB  OG   sing N N 378 
SER CB  HB2  sing N N 379 
SER CB  HB3  sing N N 380 
SER OG  HG   sing N N 381 
SER OXT HXT  sing N N 382 
THR N   CA   sing N N 383 
THR N   H    sing N N 384 
THR N   H2   sing N N 385 
THR CA  C    sing N N 386 
THR CA  CB   sing N N 387 
THR CA  HA   sing N N 388 
THR C   O    doub N N 389 
THR C   OXT  sing N N 390 
THR CB  OG1  sing N N 391 
THR CB  CG2  sing N N 392 
THR CB  HB   sing N N 393 
THR OG1 HG1  sing N N 394 
THR CG2 HG21 sing N N 395 
THR CG2 HG22 sing N N 396 
THR CG2 HG23 sing N N 397 
THR OXT HXT  sing N N 398 
TRP N   CA   sing N N 399 
TRP N   H    sing N N 400 
TRP N   H2   sing N N 401 
TRP CA  C    sing N N 402 
TRP CA  CB   sing N N 403 
TRP CA  HA   sing N N 404 
TRP C   O    doub N N 405 
TRP C   OXT  sing N N 406 
TRP CB  CG   sing N N 407 
TRP CB  HB2  sing N N 408 
TRP CB  HB3  sing N N 409 
TRP CG  CD1  doub Y N 410 
TRP CG  CD2  sing Y N 411 
TRP CD1 NE1  sing Y N 412 
TRP CD1 HD1  sing N N 413 
TRP CD2 CE2  doub Y N 414 
TRP CD2 CE3  sing Y N 415 
TRP NE1 CE2  sing Y N 416 
TRP NE1 HE1  sing N N 417 
TRP CE2 CZ2  sing Y N 418 
TRP CE3 CZ3  doub Y N 419 
TRP CE3 HE3  sing N N 420 
TRP CZ2 CH2  doub Y N 421 
TRP CZ2 HZ2  sing N N 422 
TRP CZ3 CH2  sing Y N 423 
TRP CZ3 HZ3  sing N N 424 
TRP CH2 HH2  sing N N 425 
TRP OXT HXT  sing N N 426 
TYR N   CA   sing N N 427 
TYR N   H    sing N N 428 
TYR N   H2   sing N N 429 
TYR CA  C    sing N N 430 
TYR CA  CB   sing N N 431 
TYR CA  HA   sing N N 432 
TYR C   O    doub N N 433 
TYR C   OXT  sing N N 434 
TYR CB  CG   sing N N 435 
TYR CB  HB2  sing N N 436 
TYR CB  HB3  sing N N 437 
TYR CG  CD1  doub Y N 438 
TYR CG  CD2  sing Y N 439 
TYR CD1 CE1  sing Y N 440 
TYR CD1 HD1  sing N N 441 
TYR CD2 CE2  doub Y N 442 
TYR CD2 HD2  sing N N 443 
TYR CE1 CZ   doub Y N 444 
TYR CE1 HE1  sing N N 445 
TYR CE2 CZ   sing Y N 446 
TYR CE2 HE2  sing N N 447 
TYR CZ  OH   sing N N 448 
TYR OH  HH   sing N N 449 
TYR OXT HXT  sing N N 450 
VAL N   CA   sing N N 451 
VAL N   H    sing N N 452 
VAL N   H2   sing N N 453 
VAL CA  C    sing N N 454 
VAL CA  CB   sing N N 455 
VAL CA  HA   sing N N 456 
VAL C   O    doub N N 457 
VAL C   OXT  sing N N 458 
VAL CB  CG1  sing N N 459 
VAL CB  CG2  sing N N 460 
VAL CB  HB   sing N N 461 
VAL CG1 HG11 sing N N 462 
VAL CG1 HG12 sing N N 463 
VAL CG1 HG13 sing N N 464 
VAL CG2 HG21 sing N N 465 
VAL CG2 HG22 sing N N 466 
VAL CG2 HG23 sing N N 467 
VAL OXT HXT  sing N N 468 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-21 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9FF1 
_em_admin.last_update        2025-06-04 
_em_admin.map_release_date   2025-06-04 
_em_admin.title              
'Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric desensitised state' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 137 mM NaCl   1 'sodium chloride'    
1 2.7 mM KCl    2 'potassium chloride' 
1 4.3 mM Na2HPO 3 'Disodium phosphate' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.25 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 'EXPI 293F' 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              pHLsec 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               6.43 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     20757 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   8401972 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? RELION    ?         
'IMAGE ACQUISITION'        ? 2  ? ? 1 EPU       ?         
MASKING                    ? 3  ? ? ? ?         ?         
'CTF CORRECTION'           ? 4  1 ? ? CTFFIND   4.1       
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?         
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?         
'MODEL FITTING'            ? 7  ? 1 ? PHENIX    ?         
OTHER                      ? 8  ? ? ? ?         ?         
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX    1.21_5207 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? cryoSPARC ?         
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? cryoSPARC ?         
CLASSIFICATION             ? 12 1 ? ? cryoSPARC ?         
RECONSTRUCTION             ? 13 1 ? ? cryoSPARC ?         
# 
_em_specimen.concentration           1 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)'                                           'United Kingdom' MC_UP_1201/15       1 
'Cancer Research UK'                                                                       'United Kingdom' DRCRPG-May23/100002 2 
'Medical Research Council (MRC, United Kingdom)'                                           'United Kingdom' MR/L009609/1        3 
'Medical Research Council (MRC, United Kingdom)'                                           'United Kingdom' MC_EX_MR/T046279/1  4 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States'  1R01-GM135550       5 
'National Science Foundation (NSF, United States)'                                         'United States'  'NeuroNex 2014862'  6 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 NAG 1 n 
2 NAG 2 n 
2 BMA 3 n 
2 MAN 4 n 
2 MAN 5 n 
3 NAG 1 n 
3 NAG 2 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7A5V 
# 
_atom_sites.entry_id                    9FF1 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ASN A 1 58  ? 116.305 157.109 69.027  1.00 136.94 ? 4   ASN A N   1 
ATOM   2     C CA  . ASN A 1 58  ? 116.427 158.556 68.895  1.00 147.89 ? 4   ASN A CA  1 
ATOM   3     C C   . ASN A 1 58  ? 116.071 159.264 70.201  1.00 154.95 ? 4   ASN A C   1 
ATOM   4     O O   . ASN A 1 58  ? 116.831 160.101 70.688  1.00 151.50 ? 4   ASN A O   1 
ATOM   5     C CB  . ASN A 1 58  ? 115.538 159.065 67.758  1.00 153.58 ? 4   ASN A CB  1 
ATOM   6     C CG  . ASN A 1 58  ? 115.557 160.576 67.633  1.00 158.55 ? 4   ASN A CG  1 
ATOM   7     O OD1 . ASN A 1 58  ? 116.464 161.151 67.030  1.00 157.94 ? 4   ASN A OD1 1 
ATOM   8     N ND2 . ASN A 1 58  ? 114.547 161.228 68.198  1.00 159.32 ? 4   ASN A ND2 1 
ATOM   9     N N   . ASP A 1 59  ? 114.911 158.925 70.765  1.00 160.16 ? 5   ASP A N   1 
ATOM   10    C CA  . ASP A 1 59  ? 114.476 159.544 72.006  1.00 158.28 ? 5   ASP A CA  1 
ATOM   11    C C   . ASP A 1 59  ? 115.105 158.847 73.212  1.00 154.78 ? 5   ASP A C   1 
ATOM   12    O O   . ASP A 1 59  ? 115.421 157.656 73.156  1.00 149.09 ? 5   ASP A O   1 
ATOM   13    C CB  . ASP A 1 59  ? 112.956 159.493 72.123  1.00 156.15 ? 5   ASP A CB  1 
ATOM   14    C CG  . ASP A 1 59  ? 112.259 160.314 71.055  1.00 158.92 ? 5   ASP A CG  1 
ATOM   15    O OD1 . ASP A 1 59  ? 112.841 161.323 70.604  1.00 157.94 ? 5   ASP A OD1 1 
ATOM   16    O OD2 . ASP A 1 59  ? 111.128 159.951 70.669  1.00 160.57 ? 5   ASP A OD2 1 
ATOM   17    N N   . PRO A 1 60  ? 115.308 159.576 74.312  1.00 156.44 ? 6   PRO A N   1 
ATOM   18    C CA  . PRO A 1 60  ? 115.788 158.926 75.543  1.00 155.86 ? 6   PRO A CA  1 
ATOM   19    C C   . PRO A 1 60  ? 114.827 157.887 76.094  1.00 152.83 ? 6   PRO A C   1 
ATOM   20    O O   . PRO A 1 60  ? 115.264 156.987 76.822  1.00 150.17 ? 6   PRO A O   1 
ATOM   21    C CB  . PRO A 1 60  ? 115.965 160.100 76.514  1.00 150.10 ? 6   PRO A CB  1 
ATOM   22    C CG  . PRO A 1 60  ? 116.145 161.294 75.633  1.00 150.28 ? 6   PRO A CG  1 
ATOM   23    C CD  . PRO A 1 60  ? 115.272 161.042 74.440  1.00 156.06 ? 6   PRO A CD  1 
ATOM   24    N N   . GLY A 1 61  ? 113.538 157.980 75.776  1.00 151.03 ? 7   GLY A N   1 
ATOM   25    C CA  . GLY A 1 61  ? 112.571 156.985 76.190  1.00 145.04 ? 7   GLY A CA  1 
ATOM   26    C C   . GLY A 1 61  ? 112.551 155.731 75.351  1.00 141.21 ? 7   GLY A C   1 
ATOM   27    O O   . GLY A 1 61  ? 111.781 154.810 75.635  1.00 136.34 ? 7   GLY A O   1 
ATOM   28    N N   . ASN A 1 62  ? 113.381 155.677 74.314  1.00 140.39 ? 8   ASN A N   1 
ATOM   29    C CA  . ASN A 1 62  ? 113.517 154.486 73.486  1.00 133.85 ? 8   ASN A CA  1 
ATOM   30    C C   . ASN A 1 62  ? 114.446 153.505 74.191  1.00 131.39 ? 8   ASN A C   1 
ATOM   31    O O   . ASN A 1 62  ? 115.629 153.797 74.393  1.00 130.61 ? 8   ASN A O   1 
ATOM   32    C CB  . ASN A 1 62  ? 114.056 154.873 72.111  1.00 133.76 ? 8   ASN A CB  1 
ATOM   33    C CG  . ASN A 1 62  ? 114.030 153.728 71.113  1.00 132.89 ? 8   ASN A CG  1 
ATOM   34    O OD1 . ASN A 1 62  ? 114.029 152.553 71.481  1.00 130.52 ? 8   ASN A OD1 1 
ATOM   35    N ND2 . ASN A 1 62  ? 114.012 154.077 69.833  1.00 139.12 ? 8   ASN A ND2 1 
ATOM   36    N N   . MET A 1 63  ? 113.911 152.341 74.566  1.00 128.78 ? 9   MET A N   1 
ATOM   37    C CA  . MET A 1 63  ? 114.706 151.379 75.321  1.00 124.91 ? 9   MET A CA  1 
ATOM   38    C C   . MET A 1 63  ? 115.717 150.668 74.430  1.00 120.40 ? 9   MET A C   1 
ATOM   39    O O   . MET A 1 63  ? 116.833 150.366 74.869  1.00 116.94 ? 9   MET A O   1 
ATOM   40    C CB  . MET A 1 63  ? 113.793 150.368 76.013  1.00 125.21 ? 9   MET A CB  1 
ATOM   41    C CG  . MET A 1 63  ? 112.853 150.983 77.036  1.00 126.13 ? 9   MET A CG  1 
ATOM   42    S SD  . MET A 1 63  ? 112.094 149.746 78.106  1.00 141.67 ? 9   MET A SD  1 
ATOM   43    C CE  . MET A 1 63  ? 113.542 149.071 78.916  1.00 120.39 ? 9   MET A CE  1 
ATOM   44    N N   . SER A 1 64  ? 115.345 150.385 73.180  1.00 122.66 ? 10  SER A N   1 
ATOM   45    C CA  . SER A 1 64  ? 116.272 149.717 72.272  1.00 121.71 ? 10  SER A CA  1 
ATOM   46    C C   . SER A 1 64  ? 117.477 150.597 71.966  1.00 121.12 ? 10  SER A C   1 
ATOM   47    O O   . SER A 1 64  ? 118.599 150.096 71.827  1.00 119.19 ? 10  SER A O   1 
ATOM   48    C CB  . SER A 1 64  ? 115.554 149.322 70.983  1.00 124.55 ? 10  SER A CB  1 
ATOM   49    O OG  . SER A 1 64  ? 115.077 150.465 70.299  1.00 130.33 ? 10  SER A OG  1 
ATOM   50    N N   . PHE A 1 65  ? 117.266 151.910 71.852  1.00 123.23 ? 11  PHE A N   1 
ATOM   51    C CA  . PHE A 1 65  ? 118.383 152.822 71.620  1.00 116.69 ? 11  PHE A CA  1 
ATOM   52    C C   . PHE A 1 65  ? 119.360 152.808 72.790  1.00 110.33 ? 11  PHE A C   1 
ATOM   53    O O   . PHE A 1 65  ? 120.581 152.778 72.592  1.00 106.90 ? 11  PHE A O   1 
ATOM   54    C CB  . PHE A 1 65  ? 117.854 154.234 71.369  1.00 118.41 ? 11  PHE A CB  1 
ATOM   55    C CG  . PHE A 1 65  ? 118.917 155.292 71.379  1.00 116.29 ? 11  PHE A CG  1 
ATOM   56    C CD1 . PHE A 1 65  ? 119.825 155.393 70.339  1.00 116.56 ? 11  PHE A CD1 1 
ATOM   57    C CD2 . PHE A 1 65  ? 119.000 156.195 72.424  1.00 114.41 ? 11  PHE A CD2 1 
ATOM   58    C CE1 . PHE A 1 65  ? 120.800 156.369 70.347  1.00 113.60 ? 11  PHE A CE1 1 
ATOM   59    C CE2 . PHE A 1 65  ? 119.972 157.173 72.438  1.00 111.23 ? 11  PHE A CE2 1 
ATOM   60    C CZ  . PHE A 1 65  ? 120.873 157.261 71.398  1.00 111.88 ? 11  PHE A CZ  1 
ATOM   61    N N   . VAL A 1 66  ? 118.841 152.816 74.019  1.00 110.13 ? 12  VAL A N   1 
ATOM   62    C CA  . VAL A 1 66  ? 119.708 152.765 75.192  1.00 107.09 ? 12  VAL A CA  1 
ATOM   63    C C   . VAL A 1 66  ? 120.424 151.422 75.268  1.00 107.54 ? 12  VAL A C   1 
ATOM   64    O O   . VAL A 1 66  ? 121.600 151.349 75.650  1.00 108.42 ? 12  VAL A O   1 
ATOM   65    C CB  . VAL A 1 66  ? 118.894 153.052 76.465  1.00 102.02 ? 12  VAL A CB  1 
ATOM   66    C CG1 . VAL A 1 66  ? 119.775 152.948 77.698  1.00 99.24  ? 12  VAL A CG1 1 
ATOM   67    C CG2 . VAL A 1 66  ? 118.256 154.429 76.379  1.00 104.64 ? 12  VAL A CG2 1 
ATOM   68    N N   . LYS A 1 67  ? 119.732 150.339 74.908  1.00 107.30 ? 13  LYS A N   1 
ATOM   69    C CA  . LYS A 1 67  ? 120.376 149.030 74.882  1.00 105.19 ? 13  LYS A CA  1 
ATOM   70    C C   . LYS A 1 67  ? 121.519 149.001 73.879  1.00 104.06 ? 13  LYS A C   1 
ATOM   71    O O   . LYS A 1 67  ? 122.594 148.461 74.165  1.00 101.39 ? 13  LYS A O   1 
ATOM   72    C CB  . LYS A 1 67  ? 119.356 147.943 74.553  1.00 105.88 ? 13  LYS A CB  1 
ATOM   73    C CG  . LYS A 1 67  ? 119.973 146.564 74.417  1.00 103.99 ? 13  LYS A CG  1 
ATOM   74    C CD  . LYS A 1 67  ? 118.956 145.534 73.970  1.00 108.42 ? 13  LYS A CD  1 
ATOM   75    C CE  . LYS A 1 67  ? 119.609 144.176 73.783  1.00 109.78 ? 13  LYS A CE  1 
ATOM   76    N NZ  . LYS A 1 67  ? 118.643 143.163 73.282  1.00 110.46 ? 13  LYS A NZ  1 
ATOM   77    N N   . GLU A 1 68  ? 121.304 149.576 72.693  1.00 106.69 ? 14  GLU A N   1 
ATOM   78    C CA  . GLU A 1 68  ? 122.368 149.639 71.697  1.00 106.99 ? 14  GLU A CA  1 
ATOM   79    C C   . GLU A 1 68  ? 123.527 150.494 72.187  1.00 104.23 ? 14  GLU A C   1 
ATOM   80    O O   . GLU A 1 68  ? 124.694 150.169 71.941  1.00 102.99 ? 14  GLU A O   1 
ATOM   81    C CB  . GLU A 1 68  ? 121.826 150.178 70.374  1.00 113.24 ? 14  GLU A CB  1 
ATOM   82    C CG  . GLU A 1 68  ? 120.996 149.179 69.589  1.00 118.11 ? 14  GLU A CG  1 
ATOM   83    C CD  . GLU A 1 68  ? 120.803 149.598 68.145  1.00 121.31 ? 14  GLU A CD  1 
ATOM   84    O OE1 . GLU A 1 68  ? 121.231 150.716 67.788  1.00 121.04 ? 14  GLU A OE1 1 
ATOM   85    O OE2 . GLU A 1 68  ? 120.228 148.809 67.366  1.00 118.33 ? 14  GLU A OE2 1 
ATOM   86    N N   . THR A 1 69  ? 123.226 151.595 72.878  1.00 103.07 ? 15  THR A N   1 
ATOM   87    C CA  . THR A 1 69  ? 124.284 152.432 73.437  1.00 100.40 ? 15  THR A CA  1 
ATOM   88    C C   . THR A 1 69  ? 125.128 151.650 74.437  1.00 98.51  ? 15  THR A C   1 
ATOM   89    O O   . THR A 1 69  ? 126.363 151.691 74.394  1.00 100.12 ? 15  THR A O   1 
ATOM   90    C CB  . THR A 1 69  ? 123.677 153.668 74.099  1.00 96.31  ? 15  THR A CB  1 
ATOM   91    O OG1 . THR A 1 69  ? 122.874 154.376 73.147  1.00 104.58 ? 15  THR A OG1 1 
ATOM   92    C CG2 . THR A 1 69  ? 124.772 154.586 74.613  1.00 88.77  ? 15  THR A CG2 1 
ATOM   93    N N   . VAL A 1 70  ? 124.473 150.914 75.337  1.00 95.11  ? 16  VAL A N   1 
ATOM   94    C CA  . VAL A 1 70  ? 125.203 150.136 76.335  1.00 90.87  ? 16  VAL A CA  1 
ATOM   95    C C   . VAL A 1 70  ? 126.025 149.040 75.666  1.00 91.80  ? 16  VAL A C   1 
ATOM   96    O O   . VAL A 1 70  ? 127.184 148.799 76.032  1.00 91.50  ? 16  VAL A O   1 
ATOM   97    C CB  . VAL A 1 70  ? 124.231 149.561 77.381  1.00 90.94  ? 16  VAL A CB  1 
ATOM   98    C CG1 . VAL A 1 70  ? 124.970 148.656 78.352  1.00 90.30  ? 16  VAL A CG1 1 
ATOM   99    C CG2 . VAL A 1 70  ? 123.538 150.687 78.128  1.00 87.30  ? 16  VAL A CG2 1 
ATOM   100   N N   . ASP A 1 71  ? 125.441 148.356 74.679  1.00 94.55  ? 17  ASP A N   1 
ATOM   101   C CA  . ASP A 1 71  ? 126.161 147.289 73.990  1.00 95.72  ? 17  ASP A CA  1 
ATOM   102   C C   . ASP A 1 71  ? 127.373 147.829 73.243  1.00 93.62  ? 17  ASP A C   1 
ATOM   103   O O   . ASP A 1 71  ? 128.429 147.187 73.212  1.00 94.20  ? 17  ASP A O   1 
ATOM   104   C CB  . ASP A 1 71  ? 125.220 146.555 73.035  1.00 101.75 ? 17  ASP A CB  1 
ATOM   105   C CG  . ASP A 1 71  ? 124.114 145.815 73.761  1.00 105.37 ? 17  ASP A CG  1 
ATOM   106   O OD1 . ASP A 1 71  ? 124.152 145.761 75.008  1.00 106.37 ? 17  ASP A OD1 1 
ATOM   107   O OD2 . ASP A 1 71  ? 123.205 145.289 73.086  1.00 107.09 ? 17  ASP A OD2 1 
ATOM   108   N N   . LYS A 1 72  ? 127.241 149.007 72.629  1.00 94.98  ? 18  LYS A N   1 
ATOM   109   C CA  . LYS A 1 72  ? 128.385 149.629 71.975  1.00 91.50  ? 18  LYS A CA  1 
ATOM   110   C C   . LYS A 1 72  ? 129.433 150.066 72.989  1.00 90.09  ? 18  LYS A C   1 
ATOM   111   O O   . LYS A 1 72  ? 130.632 150.033 72.693  1.00 91.09  ? 18  LYS A O   1 
ATOM   112   C CB  . LYS A 1 72  ? 127.921 150.817 71.132  1.00 89.76  ? 18  LYS A CB  1 
ATOM   113   C CG  . LYS A 1 72  ? 128.953 151.319 70.140  1.00 92.74  ? 18  LYS A CG  1 
ATOM   114   C CD  . LYS A 1 72  ? 128.356 152.365 69.214  1.00 98.86  ? 18  LYS A CD  1 
ATOM   115   C CE  . LYS A 1 72  ? 129.345 152.782 68.140  1.00 96.27  ? 18  LYS A CE  1 
ATOM   116   N NZ  . LYS A 1 72  ? 128.739 153.742 67.178  1.00 95.70  ? 18  LYS A NZ  1 
ATOM   117   N N   . LEU A 1 73  ? 129.000 150.485 74.181  1.00 90.01  ? 19  LEU A N   1 
ATOM   118   C CA  . LEU A 1 73  ? 129.949 150.799 75.244  1.00 87.88  ? 19  LEU A CA  1 
ATOM   119   C C   . LEU A 1 73  ? 130.747 149.568 75.653  1.00 87.74  ? 19  LEU A C   1 
ATOM   120   O O   . LEU A 1 73  ? 131.966 149.644 75.844  1.00 83.19  ? 19  LEU A O   1 
ATOM   121   C CB  . LEU A 1 73  ? 129.214 151.372 76.456  1.00 81.94  ? 19  LEU A CB  1 
ATOM   122   C CG  . LEU A 1 73  ? 128.702 152.807 76.372  1.00 80.32  ? 19  LEU A CG  1 
ATOM   123   C CD1 . LEU A 1 73  ? 127.989 153.188 77.658  1.00 77.60  ? 19  LEU A CD1 1 
ATOM   124   C CD2 . LEU A 1 73  ? 129.852 153.755 76.095  1.00 76.77  ? 19  LEU A CD2 1 
ATOM   125   N N   . LEU A 1 74  ? 130.076 148.428 75.793  1.00 86.92  ? 20  LEU A N   1 
ATOM   126   C CA  . LEU A 1 74  ? 130.704 147.209 76.283  1.00 79.64  ? 20  LEU A CA  1 
ATOM   127   C C   . LEU A 1 74  ? 131.306 146.350 75.179  1.00 85.08  ? 20  LEU A C   1 
ATOM   128   O O   . LEU A 1 74  ? 131.901 145.312 75.482  1.00 86.72  ? 20  LEU A O   1 
ATOM   129   C CB  . LEU A 1 74  ? 129.690 146.384 77.079  1.00 78.78  ? 20  LEU A CB  1 
ATOM   130   C CG  . LEU A 1 74  ? 129.391 146.932 78.472  1.00 83.15  ? 20  LEU A CG  1 
ATOM   131   C CD1 . LEU A 1 74  ? 128.160 146.269 79.052  1.00 82.83  ? 20  LEU A CD1 1 
ATOM   132   C CD2 . LEU A 1 74  ? 130.590 146.714 79.373  1.00 78.17  ? 20  LEU A CD2 1 
ATOM   133   N N   . LYS A 1 75  ? 131.165 146.745 73.917  1.00 88.78  ? 21  LYS A N   1 
ATOM   134   C CA  . LYS A 1 75  ? 131.768 145.984 72.832  1.00 85.63  ? 21  LYS A CA  1 
ATOM   135   C C   . LYS A 1 75  ? 133.268 146.238 72.789  1.00 85.44  ? 21  LYS A C   1 
ATOM   136   O O   . LYS A 1 75  ? 133.713 147.389 72.757  1.00 84.51  ? 21  LYS A O   1 
ATOM   137   C CB  . LYS A 1 75  ? 131.127 146.358 71.499  1.00 85.03  ? 21  LYS A CB  1 
ATOM   138   C CG  . LYS A 1 75  ? 131.670 145.579 70.316  1.00 86.71  ? 21  LYS A CG  1 
ATOM   139   C CD  . LYS A 1 75  ? 131.008 146.011 69.020  1.00 90.88  ? 21  LYS A CD  1 
ATOM   140   C CE  . LYS A 1 75  ? 131.563 145.239 67.834  1.00 92.01  ? 21  LYS A CE  1 
ATOM   141   N NZ  . LYS A 1 75  ? 130.947 145.673 66.550  1.00 92.58  ? 21  LYS A NZ  1 
ATOM   142   N N   . GLY A 1 76  ? 134.048 145.160 72.788  1.00 83.66  ? 22  GLY A N   1 
ATOM   143   C CA  . GLY A 1 76  ? 135.491 145.291 72.802  1.00 80.98  ? 22  GLY A CA  1 
ATOM   144   C C   . GLY A 1 76  ? 136.059 145.839 74.089  1.00 82.55  ? 22  GLY A C   1 
ATOM   145   O O   . GLY A 1 76  ? 137.173 146.369 74.089  1.00 82.48  ? 22  GLY A O   1 
ATOM   146   N N   . TYR A 1 77  ? 135.325 145.722 75.192  1.00 81.79  ? 23  TYR A N   1 
ATOM   147   C CA  . TYR A 1 77  ? 135.771 146.260 76.468  1.00 76.77  ? 23  TYR A CA  1 
ATOM   148   C C   . TYR A 1 77  ? 136.668 145.251 77.173  1.00 74.23  ? 23  TYR A C   1 
ATOM   149   O O   . TYR A 1 77  ? 136.276 144.098 77.382  1.00 73.20  ? 23  TYR A O   1 
ATOM   150   C CB  . TYR A 1 77  ? 134.564 146.605 77.339  1.00 77.33  ? 23  TYR A CB  1 
ATOM   151   C CG  . TYR A 1 77  ? 134.893 147.397 78.581  1.00 74.49  ? 23  TYR A CG  1 
ATOM   152   C CD1 . TYR A 1 77  ? 134.992 148.779 78.539  1.00 71.16  ? 23  TYR A CD1 1 
ATOM   153   C CD2 . TYR A 1 77  ? 135.089 146.764 79.799  1.00 69.47  ? 23  TYR A CD2 1 
ATOM   154   C CE1 . TYR A 1 77  ? 135.287 149.506 79.671  1.00 65.97  ? 23  TYR A CE1 1 
ATOM   155   C CE2 . TYR A 1 77  ? 135.383 147.483 80.935  1.00 65.65  ? 23  TYR A CE2 1 
ATOM   156   C CZ  . TYR A 1 77  ? 135.480 148.852 80.866  1.00 65.41  ? 23  TYR A CZ  1 
ATOM   157   O OH  . TYR A 1 77  ? 135.774 149.570 82.000  1.00 69.72  ? 23  TYR A OH  1 
ATOM   158   N N   . ASP A 1 78  ? 137.869 145.686 77.543  1.00 69.31  ? 24  ASP A N   1 
ATOM   159   C CA  . ASP A 1 78  ? 138.851 144.829 78.205  1.00 70.90  ? 24  ASP A CA  1 
ATOM   160   C C   . ASP A 1 78  ? 138.796 145.118 79.701  1.00 72.91  ? 24  ASP A C   1 
ATOM   161   O O   . ASP A 1 78  ? 139.217 146.185 80.155  1.00 72.05  ? 24  ASP A O   1 
ATOM   162   C CB  . ASP A 1 78  ? 140.247 145.065 77.639  1.00 69.83  ? 24  ASP A CB  1 
ATOM   163   C CG  . ASP A 1 78  ? 141.194 143.915 77.924  1.00 73.76  ? 24  ASP A CG  1 
ATOM   164   O OD1 . ASP A 1 78  ? 140.713 142.825 78.299  1.00 74.33  ? 24  ASP A OD1 1 
ATOM   165   O OD2 . ASP A 1 78  ? 142.419 144.100 77.774  1.00 74.73  ? 24  ASP A OD2 1 
ATOM   166   N N   . ILE A 1 79  ? 138.271 144.165 80.469  1.00 70.22  ? 25  ILE A N   1 
ATOM   167   C CA  . ILE A 1 79  ? 138.149 144.322 81.914  1.00 65.81  ? 25  ILE A CA  1 
ATOM   168   C C   . ILE A 1 79  ? 139.499 144.069 82.569  1.00 66.50  ? 25  ILE A C   1 
ATOM   169   O O   . ILE A 1 79  ? 139.655 144.244 83.782  1.00 72.03  ? 25  ILE A O   1 
ATOM   170   C CB  . ILE A 1 79  ? 137.077 143.382 82.493  1.00 66.00  ? 25  ILE A CB  1 
ATOM   171   C CG1 . ILE A 1 79  ? 137.570 141.934 82.470  1.00 62.49  ? 25  ILE A CG1 1 
ATOM   172   C CG2 . ILE A 1 79  ? 135.782 143.514 81.714  1.00 66.97  ? 25  ILE A CG2 1 
ATOM   173   C CD1 . ILE A 1 79  ? 136.591 140.945 83.065  1.00 66.12  ? 25  ILE A CD1 1 
ATOM   174   N N   . ARG A 1 80  ? 140.481 143.654 81.773  1.00 66.51  ? 26  ARG A N   1 
ATOM   175   C CA  . ARG A 1 80  ? 141.814 143.365 82.280  1.00 67.47  ? 26  ARG A CA  1 
ATOM   176   C C   . ARG A 1 80  ? 142.703 144.598 82.359  1.00 68.58  ? 26  ARG A C   1 
ATOM   177   O O   . ARG A 1 80  ? 143.805 144.511 82.910  1.00 70.14  ? 26  ARG A O   1 
ATOM   178   C CB  . ARG A 1 80  ? 142.489 142.305 81.404  1.00 65.96  ? 26  ARG A CB  1 
ATOM   179   C CG  . ARG A 1 80  ? 141.713 141.003 81.310  1.00 67.52  ? 26  ARG A CG  1 
ATOM   180   C CD  . ARG A 1 80  ? 142.245 140.118 80.199  1.00 70.16  ? 26  ARG A CD  1 
ATOM   181   N NE  . ARG A 1 80  ? 142.260 140.815 78.919  1.00 73.19  ? 26  ARG A NE  1 
ATOM   182   C CZ  . ARG A 1 80  ? 142.466 140.231 77.747  1.00 74.58  ? 26  ARG A CZ  1 
ATOM   183   N NH1 . ARG A 1 80  ? 142.657 138.925 77.650  1.00 77.90  ? 26  ARG A NH1 1 
ATOM   184   N NH2 . ARG A 1 80  ? 142.478 140.974 76.644  1.00 74.88  ? 26  ARG A NH2 1 
ATOM   185   N N   . LEU A 1 81  ? 142.256 145.734 81.831  1.00 66.98  ? 27  LEU A N   1 
ATOM   186   C CA  . LEU A 1 81  ? 143.050 146.952 81.801  1.00 65.61  ? 27  LEU A CA  1 
ATOM   187   C C   . LEU A 1 81  ? 142.342 148.061 82.564  1.00 67.81  ? 27  LEU A C   1 
ATOM   188   O O   . LEU A 1 81  ? 141.130 148.247 82.427  1.00 70.13  ? 27  LEU A O   1 
ATOM   189   C CB  . LEU A 1 81  ? 143.309 147.413 80.365  1.00 64.77  ? 27  LEU A CB  1 
ATOM   190   C CG  . LEU A 1 81  ? 144.057 146.448 79.450  1.00 66.46  ? 27  LEU A CG  1 
ATOM   191   C CD1 . LEU A 1 81  ? 144.264 147.082 78.087  1.00 71.19  ? 27  LEU A CD1 1 
ATOM   192   C CD2 . LEU A 1 81  ? 145.385 146.057 80.070  1.00 70.95  ? 27  LEU A CD2 1 
ATOM   193   N N   . ARG A 1 82  ? 143.110 148.791 83.364  1.00 66.98  ? 28  ARG A N   1 
ATOM   194   C CA  . ARG A 1 82  ? 142.598 149.974 84.025  1.00 61.86  ? 28  ARG A CA  1 
ATOM   195   C C   . ARG A 1 82  ? 142.374 151.086 83.005  1.00 63.94  ? 28  ARG A C   1 
ATOM   196   O O   . ARG A 1 82  ? 142.985 151.092 81.934  1.00 66.38  ? 28  ARG A O   1 
ATOM   197   C CB  . ARG A 1 82  ? 143.575 150.442 85.097  1.00 57.57  ? 28  ARG A CB  1 
ATOM   198   C CG  . ARG A 1 82  ? 144.903 150.907 84.538  1.00 58.40  ? 28  ARG A CG  1 
ATOM   199   C CD  . ARG A 1 82  ? 145.730 151.599 85.595  1.00 58.46  ? 28  ARG A CD  1 
ATOM   200   N NE  . ARG A 1 82  ? 146.977 152.124 85.053  1.00 60.54  ? 28  ARG A NE  1 
ATOM   201   C CZ  . ARG A 1 82  ? 147.104 153.317 84.491  1.00 63.74  ? 28  ARG A CZ  1 
ATOM   202   N NH1 . ARG A 1 82  ? 146.072 154.134 84.363  1.00 62.32  ? 28  ARG A NH1 1 
ATOM   203   N NH2 . ARG A 1 82  ? 148.298 153.701 84.048  1.00 66.02  ? 28  ARG A NH2 1 
ATOM   204   N N   . PRO A 1 83  ? 141.488 152.034 83.309  1.00 62.50  ? 29  PRO A N   1 
ATOM   205   C CA  . PRO A 1 83  ? 141.321 153.189 82.421  1.00 66.18  ? 29  PRO A CA  1 
ATOM   206   C C   . PRO A 1 83  ? 142.621 153.968 82.292  1.00 69.72  ? 29  PRO A C   1 
ATOM   207   O O   . PRO A 1 83  ? 143.377 154.115 83.255  1.00 65.89  ? 29  PRO A O   1 
ATOM   208   C CB  . PRO A 1 83  ? 140.232 154.014 83.114  1.00 65.91  ? 29  PRO A CB  1 
ATOM   209   C CG  . PRO A 1 83  ? 139.495 153.031 83.957  1.00 59.01  ? 29  PRO A CG  1 
ATOM   210   C CD  . PRO A 1 83  ? 140.522 152.047 84.418  1.00 59.37  ? 29  PRO A CD  1 
ATOM   211   N N   . ASP A 1 84  ? 142.871 154.472 81.084  1.00 71.96  ? 30  ASP A N   1 
ATOM   212   C CA  . ASP A 1 84  ? 144.117 155.160 80.750  1.00 74.08  ? 30  ASP A CA  1 
ATOM   213   C C   . ASP A 1 84  ? 145.326 154.282 81.065  1.00 69.97  ? 30  ASP A C   1 
ATOM   214   O O   . ASP A 1 84  ? 146.271 154.694 81.740  1.00 70.35  ? 30  ASP A O   1 
ATOM   215   C CB  . ASP A 1 84  ? 144.212 156.507 81.467  1.00 74.86  ? 30  ASP A CB  1 
ATOM   216   C CG  . ASP A 1 84  ? 143.043 157.414 81.155  1.00 84.60  ? 30  ASP A CG  1 
ATOM   217   O OD1 . ASP A 1 84  ? 142.065 156.932 80.545  1.00 85.75  ? 30  ASP A OD1 1 
ATOM   218   O OD2 . ASP A 1 84  ? 143.101 158.608 81.515  1.00 86.73  ? 30  ASP A OD2 1 
ATOM   219   N N   . PHE A 1 85  ? 145.282 153.047 80.570  1.00 66.87  ? 31  PHE A N   1 
ATOM   220   C CA  . PHE A 1 85  ? 146.384 152.120 80.778  1.00 68.04  ? 31  PHE A CA  1 
ATOM   221   C C   . PHE A 1 85  ? 147.637 152.616 80.067  1.00 69.90  ? 31  PHE A C   1 
ATOM   222   O O   . PHE A 1 85  ? 147.584 153.069 78.921  1.00 72.78  ? 31  PHE A O   1 
ATOM   223   C CB  . PHE A 1 85  ? 146.004 150.727 80.274  1.00 68.03  ? 31  PHE A CB  1 
ATOM   224   C CG  . PHE A 1 85  ? 146.968 149.650 80.678  1.00 69.89  ? 31  PHE A CG  1 
ATOM   225   C CD1 . PHE A 1 85  ? 148.073 149.359 79.894  1.00 72.29  ? 31  PHE A CD1 1 
ATOM   226   C CD2 . PHE A 1 85  ? 146.767 148.922 81.839  1.00 69.19  ? 31  PHE A CD2 1 
ATOM   227   C CE1 . PHE A 1 85  ? 148.959 148.368 80.264  1.00 74.33  ? 31  PHE A CE1 1 
ATOM   228   C CE2 . PHE A 1 85  ? 147.650 147.930 82.213  1.00 71.07  ? 31  PHE A CE2 1 
ATOM   229   C CZ  . PHE A 1 85  ? 148.747 147.653 81.425  1.00 74.38  ? 31  PHE A CZ  1 
ATOM   230   N N   . GLY A 1 86  ? 148.771 152.528 80.758  1.00 68.22  ? 32  GLY A N   1 
ATOM   231   C CA  . GLY A 1 86  ? 150.026 152.991 80.203  1.00 67.79  ? 32  GLY A CA  1 
ATOM   232   C C   . GLY A 1 86  ? 150.202 154.491 80.175  1.00 71.15  ? 32  GLY A C   1 
ATOM   233   O O   . GLY A 1 86  ? 151.174 154.974 79.587  1.00 74.80  ? 32  GLY A O   1 
ATOM   234   N N   . GLY A 1 87  ? 149.296 155.245 80.791  1.00 69.73  ? 33  GLY A N   1 
ATOM   235   C CA  . GLY A 1 87  ? 149.393 156.683 80.827  1.00 68.59  ? 33  GLY A CA  1 
ATOM   236   C C   . GLY A 1 87  ? 149.324 157.224 82.240  1.00 70.41  ? 33  GLY A C   1 
ATOM   237   O O   . GLY A 1 87  ? 149.822 156.610 83.189  1.00 70.90  ? 33  GLY A O   1 
ATOM   238   N N   . PRO A 1 88  ? 148.714 158.396 82.403  1.00 70.02  ? 34  PRO A N   1 
ATOM   239   C CA  . PRO A 1 88  ? 148.555 158.950 83.742  1.00 67.90  ? 34  PRO A CA  1 
ATOM   240   C C   . PRO A 1 88  ? 147.674 158.054 84.588  1.00 68.74  ? 34  PRO A C   1 
ATOM   241   O O   . PRO A 1 88  ? 146.760 157.383 84.072  1.00 72.55  ? 34  PRO A O   1 
ATOM   242   C CB  . PRO A 1 88  ? 147.893 160.311 83.485  1.00 63.10  ? 34  PRO A CB  1 
ATOM   243   C CG  . PRO A 1 88  ? 148.220 160.636 82.069  1.00 65.11  ? 34  PRO A CG  1 
ATOM   244   C CD  . PRO A 1 88  ? 148.247 159.321 81.359  1.00 64.79  ? 34  PRO A CD  1 
ATOM   245   N N   . PRO A 1 89  ? 147.916 158.004 85.898  1.00 62.25  ? 35  PRO A N   1 
ATOM   246   C CA  . PRO A 1 89  ? 147.109 157.138 86.762  1.00 56.42  ? 35  PRO A CA  1 
ATOM   247   C C   . PRO A 1 89  ? 145.664 157.606 86.841  1.00 57.18  ? 35  PRO A C   1 
ATOM   248   O O   . PRO A 1 89  ? 145.365 158.798 86.753  1.00 58.89  ? 35  PRO A O   1 
ATOM   249   C CB  . PRO A 1 89  ? 147.805 157.252 88.122  1.00 54.31  ? 35  PRO A CB  1 
ATOM   250   C CG  . PRO A 1 89  ? 148.469 158.582 88.081  1.00 55.22  ? 35  PRO A CG  1 
ATOM   251   C CD  . PRO A 1 89  ? 148.918 158.765 86.661  1.00 59.72  ? 35  PRO A CD  1 
ATOM   252   N N   . VAL A 1 90  ? 144.764 156.644 87.015  1.00 54.47  ? 36  VAL A N   1 
ATOM   253   C CA  . VAL A 1 90  ? 143.345 156.941 87.179  1.00 52.18  ? 36  VAL A CA  1 
ATOM   254   C C   . VAL A 1 90  ? 143.093 157.311 88.635  1.00 56.74  ? 36  VAL A C   1 
ATOM   255   O O   . VAL A 1 90  ? 143.427 156.549 89.548  1.00 62.04  ? 36  VAL A O   1 
ATOM   256   C CB  . VAL A 1 90  ? 142.476 155.753 86.742  1.00 48.87  ? 36  VAL A CB  1 
ATOM   257   C CG1 . VAL A 1 90  ? 143.060 154.445 87.251  1.00 51.41  ? 36  VAL A CG1 1 
ATOM   258   C CG2 . VAL A 1 90  ? 141.050 155.929 87.231  1.00 49.03  ? 36  VAL A CG2 1 
ATOM   259   N N   . CYS A 1 91  ? 142.509 158.485 88.856  1.00 58.18  ? 37  CYS A N   1 
ATOM   260   C CA  . CYS A 1 91  ? 142.273 158.991 90.201  1.00 55.57  ? 37  CYS A CA  1 
ATOM   261   C C   . CYS A 1 91  ? 140.911 158.527 90.696  1.00 53.14  ? 37  CYS A C   1 
ATOM   262   O O   . CYS A 1 91  ? 139.898 158.711 90.014  1.00 54.04  ? 37  CYS A O   1 
ATOM   263   C CB  . CYS A 1 91  ? 142.354 160.517 90.226  1.00 58.53  ? 37  CYS A CB  1 
ATOM   264   S SG  . CYS A 1 91  ? 143.934 161.192 89.662  1.00 83.38  ? 37  CYS A SG  1 
ATOM   265   N N   . VAL A 1 92  ? 140.891 157.927 91.883  1.00 51.39  ? 38  VAL A N   1 
ATOM   266   C CA  . VAL A 1 92  ? 139.676 157.397 92.489  1.00 47.91  ? 38  VAL A CA  1 
ATOM   267   C C   . VAL A 1 92  ? 139.346 158.227 93.720  1.00 48.89  ? 38  VAL A C   1 
ATOM   268   O O   . VAL A 1 92  ? 140.203 158.425 94.588  1.00 50.36  ? 38  VAL A O   1 
ATOM   269   C CB  . VAL A 1 92  ? 139.833 155.911 92.855  1.00 45.12  ? 38  VAL A CB  1 
ATOM   270   C CG1 . VAL A 1 92  ? 138.531 155.364 93.406  1.00 46.38  ? 38  VAL A CG1 1 
ATOM   271   C CG2 . VAL A 1 92  ? 140.278 155.113 91.647  1.00 45.17  ? 38  VAL A CG2 1 
ATOM   272   N N   . GLY A 1 93  ? 138.112 158.707 93.795  1.00 47.37  ? 39  GLY A N   1 
ATOM   273   C CA  . GLY A 1 93  ? 137.617 159.427 94.960  1.00 45.88  ? 39  GLY A CA  1 
ATOM   274   C C   . GLY A 1 93  ? 136.694 158.525 95.759  1.00 47.88  ? 39  GLY A C   1 
ATOM   275   O O   . GLY A 1 93  ? 135.884 157.795 95.188  1.00 51.81  ? 39  GLY A O   1 
ATOM   276   N N   . MET A 1 94  ? 136.823 158.572 97.079  1.00 45.56  ? 40  MET A N   1 
ATOM   277   C CA  . MET A 1 94  ? 136.121 157.641 97.949  1.00 46.33  ? 40  MET A CA  1 
ATOM   278   C C   . MET A 1 94  ? 135.300 158.378 98.993  1.00 47.22  ? 40  MET A C   1 
ATOM   279   O O   . MET A 1 94  ? 135.746 159.380 99.558  1.00 49.84  ? 40  MET A O   1 
ATOM   280   C CB  . MET A 1 94  ? 137.100 156.699 98.646  1.00 44.96  ? 40  MET A CB  1 
ATOM   281   C CG  . MET A 1 94  ? 137.839 155.789 97.699  1.00 48.11  ? 40  MET A CG  1 
ATOM   282   S SD  . MET A 1 94  ? 138.873 154.603 98.563  1.00 65.59  ? 40  MET A SD  1 
ATOM   283   C CE  . MET A 1 94  ? 139.454 153.628 97.185  1.00 51.86  ? 40  MET A CE  1 
ATOM   284   N N   A ASN A 1 95  ? 134.093 157.871 99.230  0.50 46.33  ? 41  ASN A N   1 
ATOM   285   N N   B ASN A 1 95  ? 134.096 157.876 99.256  0.50 46.00  ? 41  ASN A N   1 
ATOM   286   C CA  A ASN A 1 95  ? 133.212 158.353 100.281 0.50 47.05  ? 41  ASN A CA  1 
ATOM   287   C CA  B ASN A 1 95  ? 133.284 158.411 100.339 0.50 47.00  ? 41  ASN A CA  1 
ATOM   288   C C   A ASN A 1 95  ? 132.726 157.167 101.097 0.50 46.31  ? 41  ASN A C   1 
ATOM   289   C C   B ASN A 1 95  ? 132.570 157.278 101.062 0.50 45.99  ? 41  ASN A C   1 
ATOM   290   O O   A ASN A 1 95  ? 132.568 156.060 100.575 0.50 46.06  ? 41  ASN A O   1 
ATOM   291   O O   B ASN A 1 95  ? 132.095 156.325 100.439 0.50 46.02  ? 41  ASN A O   1 
ATOM   292   C CB  A ASN A 1 95  ? 132.007 159.106 99.716  0.50 45.50  ? 41  ASN A CB  1 
ATOM   293   C CB  B ASN A 1 95  ? 132.276 159.455 99.832  0.50 45.50  ? 41  ASN A CB  1 
ATOM   294   C CG  A ASN A 1 95  ? 132.405 160.176 98.736  0.50 47.38  ? 41  ASN A CG  1 
ATOM   295   C CG  B ASN A 1 95  ? 131.356 158.913 98.763  0.50 47.03  ? 41  ASN A CG  1 
ATOM   296   O OD1 A ASN A 1 95  ? 131.965 160.175 97.587  0.50 51.13  ? 41  ASN A OD1 1 
ATOM   297   O OD1 B ASN A 1 95  ? 131.668 158.968 97.574  0.50 50.29  ? 41  ASN A OD1 1 
ATOM   298   N ND2 A ASN A 1 95  ? 133.247 161.098 99.179  0.50 47.39  ? 41  ASN A ND2 1 
ATOM   299   N ND2 B ASN A 1 95  ? 130.206 158.400 99.180  0.50 47.04  ? 41  ASN A ND2 1 
ATOM   300   N N   . ILE A 1 96  ? 132.489 157.400 102.384 1.00 45.22  ? 42  ILE A N   1 
ATOM   301   C CA  . ILE A 1 96  ? 131.941 156.372 103.258 1.00 41.52  ? 42  ILE A CA  1 
ATOM   302   C C   . ILE A 1 96  ? 130.755 156.957 104.008 1.00 48.42  ? 42  ILE A C   1 
ATOM   303   O O   . ILE A 1 96  ? 130.862 158.033 104.606 1.00 54.99  ? 42  ILE A O   1 
ATOM   304   C CB  . ILE A 1 96  ? 133.000 155.836 104.238 1.00 42.89  ? 42  ILE A CB  1 
ATOM   305   C CG1 . ILE A 1 96  ? 134.132 155.150 103.473 1.00 42.31  ? 42  ILE A CG1 1 
ATOM   306   C CG2 . ILE A 1 96  ? 132.370 154.882 105.233 1.00 45.23  ? 42  ILE A CG2 1 
ATOM   307   C CD1 . ILE A 1 96  ? 135.220 154.597 104.358 1.00 45.79  ? 42  ILE A CD1 1 
ATOM   308   N N   . ASP A 1 97  ? 129.631 156.253 103.974 1.00 45.39  ? 43  ASP A N   1 
ATOM   309   C CA  . ASP A 1 97  ? 128.443 156.614 104.741 1.00 47.35  ? 43  ASP A CA  1 
ATOM   310   C C   . ASP A 1 97  ? 128.237 155.509 105.771 1.00 50.68  ? 43  ASP A C   1 
ATOM   311   O O   . ASP A 1 97  ? 127.728 154.436 105.445 1.00 53.32  ? 43  ASP A O   1 
ATOM   312   C CB  . ASP A 1 97  ? 127.232 156.777 103.830 1.00 51.96  ? 43  ASP A CB  1 
ATOM   313   C CG  . ASP A 1 97  ? 126.012 157.300 104.563 1.00 67.30  ? 43  ASP A CG  1 
ATOM   314   O OD1 . ASP A 1 97  ? 126.106 157.568 105.778 1.00 68.47  ? 43  ASP A OD1 1 
ATOM   315   O OD2 . ASP A 1 97  ? 124.952 157.446 103.918 1.00 72.03  ? 43  ASP A OD2 1 
ATOM   316   N N   . ILE A 1 98  ? 128.646 155.768 107.008 1.00 50.82  ? 44  ILE A N   1 
ATOM   317   C CA  . ILE A 1 98  ? 128.652 154.737 108.040 1.00 47.77  ? 44  ILE A CA  1 
ATOM   318   C C   . ILE A 1 98  ? 127.232 154.522 108.546 1.00 50.25  ? 44  ILE A C   1 
ATOM   319   O O   . ILE A 1 98  ? 126.620 155.432 109.114 1.00 60.03  ? 44  ILE A O   1 
ATOM   320   C CB  . ILE A 1 98  ? 129.593 155.115 109.189 1.00 47.99  ? 44  ILE A CB  1 
ATOM   321   C CG1 . ILE A 1 98  ? 131.048 155.025 108.734 1.00 46.49  ? 44  ILE A CG1 1 
ATOM   322   C CG2 . ILE A 1 98  ? 129.343 154.220 110.386 1.00 50.12  ? 44  ILE A CG2 1 
ATOM   323   C CD1 . ILE A 1 98  ? 132.038 155.386 109.809 1.00 53.63  ? 44  ILE A CD1 1 
ATOM   324   N N   . ALA A 1 99  ? 126.705 153.314 108.342 1.00 45.47  ? 45  ALA A N   1 
ATOM   325   C CA  . ALA A 1 99  ? 125.377 152.997 108.851 1.00 47.45  ? 45  ALA A CA  1 
ATOM   326   C C   . ALA A 1 99  ? 125.396 152.803 110.362 1.00 54.66  ? 45  ALA A C   1 
ATOM   327   O O   . ALA A 1 99  ? 124.524 153.321 111.068 1.00 68.54  ? 45  ALA A O   1 
ATOM   328   C CB  . ALA A 1 99  ? 124.830 151.752 108.154 1.00 43.05  ? 45  ALA A CB  1 
ATOM   329   N N   . SER A 1 100 ? 126.388 152.076 110.875 1.00 46.54  ? 46  SER A N   1 
ATOM   330   C CA  . SER A 1 100 ? 126.479 151.785 112.301 1.00 52.46  ? 46  SER A CA  1 
ATOM   331   C C   . SER A 1 100 ? 127.801 151.092 112.591 1.00 51.35  ? 46  SER A C   1 
ATOM   332   O O   . SER A 1 100 ? 128.410 150.482 111.708 1.00 53.26  ? 46  SER A O   1 
ATOM   333   C CB  . SER A 1 100 ? 125.316 150.907 112.774 1.00 56.29  ? 46  SER A CB  1 
ATOM   334   O OG  . SER A 1 100 ? 125.323 149.654 112.112 1.00 53.33  ? 46  SER A OG  1 
ATOM   335   N N   . ILE A 1 101 ? 128.233 151.194 113.845 1.00 49.27  ? 47  ILE A N   1 
ATOM   336   C CA  . ILE A 1 101 ? 129.329 150.399 114.386 1.00 47.63  ? 47  ILE A CA  1 
ATOM   337   C C   . ILE A 1 101 ? 128.690 149.393 115.335 1.00 51.22  ? 47  ILE A C   1 
ATOM   338   O O   . ILE A 1 101 ? 128.289 149.740 116.450 1.00 56.42  ? 47  ILE A O   1 
ATOM   339   C CB  . ILE A 1 101 ? 130.380 151.261 115.094 1.00 45.82  ? 47  ILE A CB  1 
ATOM   340   C CG1 . ILE A 1 101 ? 131.035 152.222 114.103 1.00 49.44  ? 47  ILE A CG1 1 
ATOM   341   C CG2 . ILE A 1 101 ? 131.430 150.384 115.751 1.00 46.19  ? 47  ILE A CG2 1 
ATOM   342   C CD1 . ILE A 1 101 ? 132.161 153.036 114.695 1.00 50.35  ? 47  ILE A CD1 1 
ATOM   343   N N   . ASP A 1 102 ? 128.592 148.138 114.889 1.00 53.07  ? 48  ASP A N   1 
ATOM   344   C CA  . ASP A 1 102 ? 127.759 147.160 115.583 1.00 57.65  ? 48  ASP A CA  1 
ATOM   345   C C   . ASP A 1 102 ? 128.327 146.801 116.951 1.00 63.55  ? 48  ASP A C   1 
ATOM   346   O O   . ASP A 1 102 ? 127.600 146.795 117.951 1.00 70.45  ? 48  ASP A O   1 
ATOM   347   C CB  . ASP A 1 102 ? 127.602 145.910 114.719 1.00 60.00  ? 48  ASP A CB  1 
ATOM   348   C CG  . ASP A 1 102 ? 127.027 146.219 113.353 1.00 63.98  ? 48  ASP A CG  1 
ATOM   349   O OD1 . ASP A 1 102 ? 126.219 147.165 113.249 1.00 61.33  ? 48  ASP A OD1 1 
ATOM   350   O OD2 . ASP A 1 102 ? 127.385 145.520 112.382 1.00 62.91  ? 48  ASP A OD2 1 
ATOM   351   N N   . MET A 1 103 ? 129.620 146.495 117.020 1.00 63.88  ? 49  MET A N   1 
ATOM   352   C CA  . MET A 1 103 ? 130.216 146.072 118.278 1.00 63.38  ? 49  MET A CA  1 
ATOM   353   C C   . MET A 1 103 ? 131.683 146.469 118.309 1.00 65.99  ? 49  MET A C   1 
ATOM   354   O O   . MET A 1 103 ? 132.320 146.657 117.271 1.00 68.65  ? 49  MET A O   1 
ATOM   355   C CB  . MET A 1 103 ? 130.075 144.561 118.488 1.00 63.71  ? 49  MET A CB  1 
ATOM   356   C CG  . MET A 1 103 ? 130.813 143.723 117.459 1.00 67.38  ? 49  MET A CG  1 
ATOM   357   S SD  . MET A 1 103 ? 130.759 141.959 117.823 1.00 107.36 ? 49  MET A SD  1 
ATOM   358   C CE  . MET A 1 103 ? 128.994 141.662 117.798 1.00 97.15  ? 49  MET A CE  1 
ATOM   359   N N   . VAL A 1 104 ? 132.210 146.594 119.524 1.00 61.85  ? 50  VAL A N   1 
ATOM   360   C CA  . VAL A 1 104 ? 133.621 146.880 119.764 1.00 58.49  ? 50  VAL A CA  1 
ATOM   361   C C   . VAL A 1 104 ? 134.083 145.854 120.790 1.00 61.86  ? 50  VAL A C   1 
ATOM   362   O O   . VAL A 1 104 ? 133.922 146.060 121.998 1.00 70.55  ? 50  VAL A O   1 
ATOM   363   C CB  . VAL A 1 104 ? 133.857 148.310 120.263 1.00 56.62  ? 50  VAL A CB  1 
ATOM   364   C CG1 . VAL A 1 104 ? 135.345 148.601 120.363 1.00 59.18  ? 50  VAL A CG1 1 
ATOM   365   C CG2 . VAL A 1 104 ? 133.175 149.317 119.351 1.00 56.04  ? 50  VAL A CG2 1 
ATOM   366   N N   . SER A 1 105 ? 134.649 144.745 120.320 1.00 59.41  ? 51  SER A N   1 
ATOM   367   C CA  . SER A 1 105 ? 135.029 143.640 121.187 1.00 64.06  ? 51  SER A CA  1 
ATOM   368   C C   . SER A 1 105 ? 136.485 143.794 121.605 1.00 64.84  ? 51  SER A C   1 
ATOM   369   O O   . SER A 1 105 ? 137.387 143.792 120.757 1.00 62.48  ? 51  SER A O   1 
ATOM   370   C CB  . SER A 1 105 ? 134.813 142.304 120.478 1.00 68.77  ? 51  SER A CB  1 
ATOM   371   O OG  . SER A 1 105 ? 135.192 141.218 121.304 1.00 71.81  ? 51  SER A OG  1 
ATOM   372   N N   . GLU A 1 106 ? 136.708 143.942 122.914 1.00 68.17  ? 52  GLU A N   1 
ATOM   373   C CA  . GLU A 1 106 ? 138.060 143.919 123.456 1.00 66.86  ? 52  GLU A CA  1 
ATOM   374   C C   . GLU A 1 106 ? 138.621 142.506 123.513 1.00 67.47  ? 52  GLU A C   1 
ATOM   375   O O   . GLU A 1 106 ? 139.844 142.329 123.497 1.00 67.09  ? 52  GLU A O   1 
ATOM   376   C CB  . GLU A 1 106 ? 138.087 144.541 124.855 1.00 64.60  ? 52  GLU A CB  1 
ATOM   377   C CG  . GLU A 1 106 ? 137.694 146.009 124.910 1.00 63.03  ? 52  GLU A CG  1 
ATOM   378   C CD  . GLU A 1 106 ? 136.196 146.210 124.995 1.00 67.26  ? 52  GLU A CD  1 
ATOM   379   O OE1 . GLU A 1 106 ? 135.480 145.228 125.280 1.00 69.98  ? 52  GLU A OE1 1 
ATOM   380   O OE2 . GLU A 1 106 ? 135.732 147.350 124.778 1.00 63.66  ? 52  GLU A OE2 1 
ATOM   381   N N   . VAL A 1 107 ? 137.750 141.497 123.594 1.00 69.81  ? 53  VAL A N   1 
ATOM   382   C CA  . VAL A 1 107 ? 138.213 140.112 123.636 1.00 71.42  ? 53  VAL A CA  1 
ATOM   383   C C   . VAL A 1 107 ? 138.961 139.766 122.356 1.00 72.90  ? 53  VAL A C   1 
ATOM   384   O O   . VAL A 1 107 ? 140.078 139.236 122.390 1.00 77.49  ? 53  VAL A O   1 
ATOM   385   C CB  . VAL A 1 107 ? 137.030 139.157 123.873 1.00 71.27  ? 53  VAL A CB  1 
ATOM   386   C CG1 . VAL A 1 107 ? 137.521 137.724 123.991 1.00 72.08  ? 53  VAL A CG1 1 
ATOM   387   C CG2 . VAL A 1 107 ? 136.258 139.567 125.114 1.00 73.44  ? 53  VAL A CG2 1 
ATOM   388   N N   . ASN A 1 108 ? 138.356 140.064 121.207 1.00 70.06  ? 54  ASN A N   1 
ATOM   389   C CA  . ASN A 1 108 ? 139.004 139.871 119.918 1.00 66.50  ? 54  ASN A CA  1 
ATOM   390   C C   . ASN A 1 108 ? 139.804 141.086 119.473 1.00 70.09  ? 54  ASN A C   1 
ATOM   391   O O   . ASN A 1 108 ? 140.510 141.003 118.461 1.00 69.66  ? 54  ASN A O   1 
ATOM   392   C CB  . ASN A 1 108 ? 137.963 139.536 118.843 1.00 65.37  ? 54  ASN A CB  1 
ATOM   393   C CG  . ASN A 1 108 ? 137.079 138.366 119.226 1.00 70.62  ? 54  ASN A CG  1 
ATOM   394   O OD1 . ASN A 1 108 ? 137.336 137.227 118.841 1.00 79.34  ? 54  ASN A OD1 1 
ATOM   395   N ND2 . ASN A 1 108 ? 136.024 138.646 119.982 1.00 70.02  ? 54  ASN A ND2 1 
ATOM   396   N N   . MET A 1 109 ? 139.715 142.197 120.202 1.00 72.37  ? 55  MET A N   1 
ATOM   397   C CA  . MET A 1 109 ? 140.376 143.452 119.848 1.00 70.94  ? 55  MET A CA  1 
ATOM   398   C C   . MET A 1 109 ? 140.039 143.865 118.415 1.00 65.68  ? 55  MET A C   1 
ATOM   399   O O   . MET A 1 109 ? 140.914 144.058 117.570 1.00 60.82  ? 55  MET A O   1 
ATOM   400   C CB  . MET A 1 109 ? 141.890 143.353 120.048 1.00 70.28  ? 55  MET A CB  1 
ATOM   401   C CG  . MET A 1 109 ? 142.333 143.437 121.496 1.00 80.66  ? 55  MET A CG  1 
ATOM   402   S SD  . MET A 1 109 ? 144.124 143.535 121.655 1.00 111.72 ? 55  MET A SD  1 
ATOM   403   C CE  . MET A 1 109 ? 144.293 143.798 123.418 1.00 80.82  ? 55  MET A CE  1 
ATOM   404   N N   . ASP A 1 110 ? 138.741 144.003 118.154 1.00 67.43  ? 56  ASP A N   1 
ATOM   405   C CA  . ASP A 1 110 ? 138.294 144.388 116.823 1.00 60.88  ? 56  ASP A CA  1 
ATOM   406   C C   . ASP A 1 110 ? 136.921 145.035 116.918 1.00 60.24  ? 56  ASP A C   1 
ATOM   407   O O   . ASP A 1 110 ? 136.174 144.814 117.873 1.00 65.74  ? 56  ASP A O   1 
ATOM   408   C CB  . ASP A 1 110 ? 138.264 143.185 115.871 1.00 61.57  ? 56  ASP A CB  1 
ATOM   409   C CG  . ASP A 1 110 ? 137.415 142.041 116.394 1.00 69.42  ? 56  ASP A CG  1 
ATOM   410   O OD1 . ASP A 1 110 ? 136.852 142.159 117.502 1.00 71.47  ? 56  ASP A OD1 1 
ATOM   411   O OD2 . ASP A 1 110 ? 137.311 141.014 115.692 1.00 70.61  ? 56  ASP A OD2 1 
ATOM   412   N N   . TYR A 1 111 ? 136.589 145.822 115.902 1.00 56.78  ? 57  TYR A N   1 
ATOM   413   C CA  . TYR A 1 111 ? 135.308 146.509 115.843 1.00 58.03  ? 57  TYR A CA  1 
ATOM   414   C C   . TYR A 1 111 ? 134.593 146.162 114.546 1.00 57.60  ? 57  TYR A C   1 
ATOM   415   O O   . TYR A 1 111 ? 135.215 146.085 113.482 1.00 58.45  ? 57  TYR A O   1 
ATOM   416   C CB  . TYR A 1 111 ? 135.482 148.028 115.971 1.00 55.39  ? 57  TYR A CB  1 
ATOM   417   C CG  . TYR A 1 111 ? 136.197 148.689 114.815 1.00 56.51  ? 57  TYR A CG  1 
ATOM   418   C CD1 . TYR A 1 111 ? 137.581 148.711 114.747 1.00 58.28  ? 57  TYR A CD1 1 
ATOM   419   C CD2 . TYR A 1 111 ? 135.484 149.310 113.800 1.00 61.15  ? 57  TYR A CD2 1 
ATOM   420   C CE1 . TYR A 1 111 ? 138.234 149.320 113.696 1.00 62.08  ? 57  TYR A CE1 1 
ATOM   421   C CE2 . TYR A 1 111 ? 136.128 149.920 112.746 1.00 62.36  ? 57  TYR A CE2 1 
ATOM   422   C CZ  . TYR A 1 111 ? 137.503 149.922 112.699 1.00 62.28  ? 57  TYR A CZ  1 
ATOM   423   O OH  . TYR A 1 111 ? 138.148 150.530 111.648 1.00 63.62  ? 57  TYR A OH  1 
ATOM   424   N N   . THR A 1 112 ? 133.283 145.956 114.643 1.00 54.45  ? 58  THR A N   1 
ATOM   425   C CA  . THR A 1 112 ? 132.448 145.609 113.502 1.00 51.38  ? 58  THR A CA  1 
ATOM   426   C C   . THR A 1 112 ? 131.755 146.861 112.985 1.00 51.45  ? 58  THR A C   1 
ATOM   427   O O   . THR A 1 112 ? 131.123 147.591 113.755 1.00 56.68  ? 58  THR A O   1 
ATOM   428   C CB  . THR A 1 112 ? 131.414 144.549 113.878 1.00 54.95  ? 58  THR A CB  1 
ATOM   429   O OG1 . THR A 1 112 ? 132.083 143.338 114.249 1.00 60.32  ? 58  THR A OG1 1 
ATOM   430   C CG2 . THR A 1 112 ? 130.492 144.268 112.707 1.00 52.50  ? 58  THR A CG2 1 
ATOM   431   N N   . LEU A 1 113 ? 131.873 147.097 111.684 1.00 47.67  ? 59  LEU A N   1 
ATOM   432   C CA  . LEU A 1 113 ? 131.417 148.322 111.053 1.00 43.16  ? 59  LEU A CA  1 
ATOM   433   C C   . LEU A 1 113 ? 130.568 147.984 109.838 1.00 44.75  ? 59  LEU A C   1 
ATOM   434   O O   . LEU A 1 113 ? 130.818 146.997 109.146 1.00 50.86  ? 59  LEU A O   1 
ATOM   435   C CB  . LEU A 1 113 ? 132.614 149.188 110.639 1.00 41.30  ? 59  LEU A CB  1 
ATOM   436   C CG  . LEU A 1 113 ? 132.358 150.424 109.783 1.00 46.05  ? 59  LEU A CG  1 
ATOM   437   C CD1 . LEU A 1 113 ? 131.585 151.446 110.581 1.00 50.90  ? 59  LEU A CD1 1 
ATOM   438   C CD2 . LEU A 1 113 ? 133.667 151.007 109.281 1.00 51.25  ? 59  LEU A CD2 1 
ATOM   439   N N   . THR A 1 114 ? 129.552 148.806 109.588 1.00 41.48  ? 60  THR A N   1 
ATOM   440   C CA  . THR A 1 114 ? 128.730 148.692 108.392 1.00 39.58  ? 60  THR A CA  1 
ATOM   441   C C   . THR A 1 114 ? 128.727 150.031 107.676 1.00 43.06  ? 60  THR A C   1 
ATOM   442   O O   . THR A 1 114 ? 128.531 151.074 108.303 1.00 54.41  ? 60  THR A O   1 
ATOM   443   C CB  . THR A 1 114 ? 127.298 148.274 108.729 1.00 42.39  ? 60  THR A CB  1 
ATOM   444   O OG1 . THR A 1 114 ? 127.315 147.030 109.436 1.00 46.91  ? 60  THR A OG1 1 
ATOM   445   C CG2 . THR A 1 114 ? 126.476 148.115 107.461 1.00 38.01  ? 60  THR A CG2 1 
ATOM   446   N N   . MET A 1 115 ? 128.925 150.009 106.360 1.00 35.03  ? 61  MET A N   1 
ATOM   447   C CA  . MET A 1 115 ? 129.085 151.265 105.646 1.00 35.34  ? 61  MET A CA  1 
ATOM   448   C C   . MET A 1 115 ? 128.617 151.137 104.207 1.00 35.77  ? 61  MET A C   1 
ATOM   449   O O   . MET A 1 115 ? 128.554 150.043 103.640 1.00 39.60  ? 61  MET A O   1 
ATOM   450   C CB  . MET A 1 115 ? 130.543 151.730 105.678 1.00 40.42  ? 61  MET A CB  1 
ATOM   451   C CG  . MET A 1 115 ? 131.522 150.645 105.289 1.00 38.36  ? 61  MET A CG  1 
ATOM   452   S SD  . MET A 1 115 ? 133.240 151.158 105.402 1.00 48.77  ? 61  MET A SD  1 
ATOM   453   C CE  . MET A 1 115 ? 134.045 149.566 105.315 1.00 43.71  ? 61  MET A CE  1 
ATOM   454   N N   . TYR A 1 116 ? 128.275 152.288 103.629 1.00 36.16  ? 62  TYR A N   1 
ATOM   455   C CA  . TYR A 1 116 ? 128.097 152.452 102.194 1.00 36.20  ? 62  TYR A CA  1 
ATOM   456   C C   . TYR A 1 116 ? 129.386 153.059 101.660 1.00 40.03  ? 62  TYR A C   1 
ATOM   457   O O   . TYR A 1 116 ? 129.650 154.247 101.865 1.00 49.83  ? 62  TYR A O   1 
ATOM   458   C CB  . TYR A 1 116 ? 126.906 153.352 101.876 1.00 44.57  ? 62  TYR A CB  1 
ATOM   459   C CG  . TYR A 1 116 ? 125.590 152.895 102.457 1.00 45.49  ? 62  TYR A CG  1 
ATOM   460   C CD1 . TYR A 1 116 ? 125.231 153.222 103.755 1.00 49.23  ? 62  TYR A CD1 1 
ATOM   461   C CD2 . TYR A 1 116 ? 124.697 152.155 101.698 1.00 45.77  ? 62  TYR A CD2 1 
ATOM   462   C CE1 . TYR A 1 116 ? 124.028 152.814 104.286 1.00 51.55  ? 62  TYR A CE1 1 
ATOM   463   C CE2 . TYR A 1 116 ? 123.491 151.743 102.221 1.00 49.91  ? 62  TYR A CE2 1 
ATOM   464   C CZ  . TYR A 1 116 ? 123.162 152.075 103.516 1.00 53.61  ? 62  TYR A CZ  1 
ATOM   465   O OH  . TYR A 1 116 ? 121.959 151.666 104.044 1.00 57.91  ? 62  TYR A OH  1 
ATOM   466   N N   . PHE A 1 117 ? 130.188 152.241 100.994 1.00 34.44  ? 63  PHE A N   1 
ATOM   467   C CA  . PHE A 1 117 ? 131.491 152.634 100.484 1.00 37.60  ? 63  PHE A CA  1 
ATOM   468   C C   . PHE A 1 117 ? 131.346 152.918 98.996  1.00 40.07  ? 63  PHE A C   1 
ATOM   469   O O   . PHE A 1 117 ? 130.946 152.032 98.232  1.00 47.44  ? 63  PHE A O   1 
ATOM   470   C CB  . PHE A 1 117 ? 132.502 151.519 100.750 1.00 37.04  ? 63  PHE A CB  1 
ATOM   471   C CG  . PHE A 1 117 ? 133.868 151.782 100.205 1.00 36.00  ? 63  PHE A CG  1 
ATOM   472   C CD1 . PHE A 1 117 ? 134.739 152.633 100.858 1.00 42.00  ? 63  PHE A CD1 1 
ATOM   473   C CD2 . PHE A 1 117 ? 134.295 151.147 99.055  1.00 33.80  ? 63  PHE A CD2 1 
ATOM   474   C CE1 . PHE A 1 117 ? 136.002 152.862 100.361 1.00 41.10  ? 63  PHE A CE1 1 
ATOM   475   C CE2 . PHE A 1 117 ? 135.554 151.371 98.555  1.00 39.98  ? 63  PHE A CE2 1 
ATOM   476   C CZ  . PHE A 1 117 ? 136.409 152.230 99.207  1.00 44.13  ? 63  PHE A CZ  1 
ATOM   477   N N   . GLN A 1 118 ? 131.646 154.148 98.583  1.00 41.04  ? 64  GLN A N   1 
ATOM   478   C CA  . GLN A 1 118 ? 131.426 154.580 97.212  1.00 42.06  ? 64  GLN A CA  1 
ATOM   479   C C   . GLN A 1 118 ? 132.733 155.065 96.609  1.00 42.44  ? 64  GLN A C   1 
ATOM   480   O O   . GLN A 1 118 ? 133.460 155.849 97.231  1.00 45.28  ? 64  GLN A O   1 
ATOM   481   C CB  . GLN A 1 118 ? 130.368 155.682 97.145  1.00 41.91  ? 64  GLN A CB  1 
ATOM   482   C CG  . GLN A 1 118 ? 129.075 155.322 97.847  1.00 45.98  ? 64  GLN A CG  1 
ATOM   483   C CD  . GLN A 1 118 ? 127.936 156.245 97.479  1.00 61.16  ? 64  GLN A CD  1 
ATOM   484   O OE1 . GLN A 1 118 ? 128.125 157.228 96.764  1.00 65.17  ? 64  GLN A OE1 1 
ATOM   485   N NE2 . GLN A 1 118 ? 126.740 155.929 97.961  1.00 65.64  ? 64  GLN A NE2 1 
ATOM   486   N N   . GLN A 1 119 ? 133.014 154.599 95.395  1.00 40.27  ? 65  GLN A N   1 
ATOM   487   C CA  . GLN A 1 119 ? 134.193 154.960 94.630  1.00 41.06  ? 65  GLN A CA  1 
ATOM   488   C C   . GLN A 1 119 ? 133.765 155.658 93.349  1.00 44.05  ? 65  GLN A C   1 
ATOM   489   O O   . GLN A 1 119 ? 132.719 155.354 92.769  1.00 50.11  ? 65  GLN A O   1 
ATOM   490   C CB  . GLN A 1 119 ? 135.041 153.729 94.303  1.00 41.34  ? 65  GLN A CB  1 
ATOM   491   C CG  . GLN A 1 119 ? 135.676 153.096 95.523  1.00 42.72  ? 65  GLN A CG  1 
ATOM   492   C CD  . GLN A 1 119 ? 136.298 151.750 95.229  1.00 47.00  ? 65  GLN A CD  1 
ATOM   493   O OE1 . GLN A 1 119 ? 137.495 151.651 94.964  1.00 49.33  ? 65  GLN A OE1 1 
ATOM   494   N NE2 . GLN A 1 119 ? 135.487 150.701 95.280  1.00 44.90  ? 65  GLN A NE2 1 
ATOM   495   N N   . TYR A 1 120 ? 134.587 156.608 92.920  1.00 43.25  ? 66  TYR A N   1 
ATOM   496   C CA  . TYR A 1 120 ? 134.229 157.535 91.857  1.00 45.56  ? 66  TYR A CA  1 
ATOM   497   C C   . TYR A 1 120 ? 135.445 157.699 90.964  1.00 48.72  ? 66  TYR A C   1 
ATOM   498   O O   . TYR A 1 120 ? 136.491 158.159 91.433  1.00 53.65  ? 66  TYR A O   1 
ATOM   499   C CB  . TYR A 1 120 ? 133.805 158.874 92.467  1.00 54.60  ? 66  TYR A CB  1 
ATOM   500   C CG  . TYR A 1 120 ? 132.963 159.771 91.599  1.00 62.24  ? 66  TYR A CG  1 
ATOM   501   C CD1 . TYR A 1 120 ? 131.638 159.464 91.329  1.00 62.83  ? 66  TYR A CD1 1 
ATOM   502   C CD2 . TYR A 1 120 ? 133.480 160.952 91.090  1.00 62.33  ? 66  TYR A CD2 1 
ATOM   503   C CE1 . TYR A 1 120 ? 130.860 160.295 90.549  1.00 70.77  ? 66  TYR A CE1 1 
ATOM   504   C CE2 . TYR A 1 120 ? 132.711 161.790 90.312  1.00 62.64  ? 66  TYR A CE2 1 
ATOM   505   C CZ  . TYR A 1 120 ? 131.401 161.458 90.046  1.00 72.99  ? 66  TYR A CZ  1 
ATOM   506   O OH  . TYR A 1 120 ? 130.630 162.289 89.267  1.00 76.92  ? 66  TYR A OH  1 
ATOM   507   N N   . TRP A 1 121 ? 135.328 157.313 89.695  1.00 49.58  ? 67  TRP A N   1 
ATOM   508   C CA  . TRP A 1 121 ? 136.466 157.446 88.790  1.00 48.17  ? 67  TRP A CA  1 
ATOM   509   C C   . TRP A 1 121 ? 135.948 157.736 87.390  1.00 49.94  ? 67  TRP A C   1 
ATOM   510   O O   . TRP A 1 121 ? 134.748 157.893 87.178  1.00 58.61  ? 67  TRP A O   1 
ATOM   511   C CB  . TRP A 1 121 ? 137.366 156.203 88.830  1.00 48.31  ? 67  TRP A CB  1 
ATOM   512   C CG  . TRP A 1 121 ? 136.798 154.980 88.183  1.00 48.04  ? 67  TRP A CG  1 
ATOM   513   C CD1 . TRP A 1 121 ? 136.958 154.592 86.886  1.00 48.89  ? 67  TRP A CD1 1 
ATOM   514   C CD2 . TRP A 1 121 ? 136.004 153.968 88.809  1.00 47.43  ? 67  TRP A CD2 1 
ATOM   515   N NE1 . TRP A 1 121 ? 136.302 153.408 86.662  1.00 48.48  ? 67  TRP A NE1 1 
ATOM   516   C CE2 . TRP A 1 121 ? 135.707 153.004 87.828  1.00 45.94  ? 67  TRP A CE2 1 
ATOM   517   C CE3 . TRP A 1 121 ? 135.508 153.787 90.103  1.00 47.57  ? 67  TRP A CE3 1 
ATOM   518   C CZ2 . TRP A 1 121 ? 134.938 151.877 88.099  1.00 46.06  ? 67  TRP A CZ2 1 
ATOM   519   C CZ3 . TRP A 1 121 ? 134.744 152.669 90.370  1.00 47.19  ? 67  TRP A CZ3 1 
ATOM   520   C CH2 . TRP A 1 121 ? 134.467 151.727 89.373  1.00 46.23  ? 67  TRP A CH2 1 
ATOM   521   N N   . ARG A 1 122 ? 136.864 157.837 86.429  1.00 48.65  ? 68  ARG A N   1 
ATOM   522   C CA  . ARG A 1 122 ? 136.502 158.166 85.053  1.00 57.30  ? 68  ARG A CA  1 
ATOM   523   C C   . ARG A 1 122 ? 137.112 157.135 84.115  1.00 61.23  ? 68  ARG A C   1 
ATOM   524   O O   . ARG A 1 122 ? 138.338 157.028 84.016  1.00 64.35  ? 68  ARG A O   1 
ATOM   525   C CB  . ARG A 1 122 ? 136.958 159.576 84.677  1.00 58.36  ? 68  ARG A CB  1 
ATOM   526   C CG  . ARG A 1 122 ? 136.555 159.989 83.268  1.00 62.30  ? 68  ARG A CG  1 
ATOM   527   C CD  . ARG A 1 122 ? 136.909 161.438 82.977  1.00 70.33  ? 68  ARG A CD  1 
ATOM   528   N NE  . ARG A 1 122 ? 136.521 161.831 81.627  1.00 84.46  ? 68  ARG A NE  1 
ATOM   529   C CZ  . ARG A 1 122 ? 136.683 163.047 81.123  1.00 94.53  ? 68  ARG A CZ  1 
ATOM   530   N NH1 . ARG A 1 122 ? 137.219 164.025 81.835  1.00 99.55  ? 68  ARG A NH1 1 
ATOM   531   N NH2 . ARG A 1 122 ? 136.298 163.288 79.873  1.00 94.87  ? 68  ARG A NH2 1 
ATOM   532   N N   . ASP A 1 123 ? 136.257 156.383 83.430  1.00 58.66  ? 69  ASP A N   1 
ATOM   533   C CA  . ASP A 1 123 ? 136.669 155.440 82.396  1.00 60.26  ? 69  ASP A CA  1 
ATOM   534   C C   . ASP A 1 123 ? 136.144 155.980 81.071  1.00 67.23  ? 69  ASP A C   1 
ATOM   535   O O   . ASP A 1 123 ? 134.947 155.891 80.785  1.00 72.35  ? 69  ASP A O   1 
ATOM   536   C CB  . ASP A 1 123 ? 136.142 154.038 82.686  1.00 63.43  ? 69  ASP A CB  1 
ATOM   537   C CG  . ASP A 1 123 ? 136.755 152.983 81.784  1.00 67.90  ? 69  ASP A CG  1 
ATOM   538   O OD1 . ASP A 1 123 ? 137.617 153.333 80.951  1.00 72.04  ? 69  ASP A OD1 1 
ATOM   539   O OD2 . ASP A 1 123 ? 136.379 151.800 81.911  1.00 68.97  ? 69  ASP A OD2 1 
ATOM   540   N N   . LYS A 1 124 ? 137.046 156.543 80.264  1.00 68.37  ? 70  LYS A N   1 
ATOM   541   C CA  . LYS A 1 124 ? 136.645 157.163 79.006  1.00 67.39  ? 70  LYS A CA  1 
ATOM   542   C C   . LYS A 1 124 ? 136.010 156.170 78.043  1.00 68.16  ? 70  LYS A C   1 
ATOM   543   O O   . LYS A 1 124 ? 135.264 156.583 77.149  1.00 72.74  ? 70  LYS A O   1 
ATOM   544   C CB  . LYS A 1 124 ? 137.849 157.833 78.347  1.00 72.01  ? 70  LYS A CB  1 
ATOM   545   C CG  . LYS A 1 124 ? 138.481 158.922 79.192  1.00 78.57  ? 70  LYS A CG  1 
ATOM   546   C CD  . LYS A 1 124 ? 139.682 159.527 78.493  1.00 81.12  ? 70  LYS A CD  1 
ATOM   547   C CE  . LYS A 1 124 ? 140.332 160.598 79.350  1.00 83.76  ? 70  LYS A CE  1 
ATOM   548   N NZ  . LYS A 1 124 ? 141.524 161.187 78.683  1.00 83.18  ? 70  LYS A NZ  1 
ATOM   549   N N   . ARG A 1 125 ? 136.290 154.875 78.200  1.00 67.04  ? 71  ARG A N   1 
ATOM   550   C CA  . ARG A 1 125 ? 135.672 153.868 77.347  1.00 67.33  ? 71  ARG A CA  1 
ATOM   551   C C   . ARG A 1 125 ? 134.169 153.765 77.568  1.00 70.04  ? 71  ARG A C   1 
ATOM   552   O O   . ARG A 1 125 ? 133.462 153.237 76.703  1.00 74.66  ? 71  ARG A O   1 
ATOM   553   C CB  . ARG A 1 125 ? 136.325 152.508 77.589  1.00 65.25  ? 71  ARG A CB  1 
ATOM   554   C CG  . ARG A 1 125 ? 137.816 152.482 77.313  1.00 67.02  ? 71  ARG A CG  1 
ATOM   555   C CD  . ARG A 1 125 ? 138.442 151.190 77.800  1.00 68.71  ? 71  ARG A CD  1 
ATOM   556   N NE  . ARG A 1 125 ? 138.361 151.060 79.250  1.00 70.76  ? 71  ARG A NE  1 
ATOM   557   C CZ  . ARG A 1 125 ? 138.863 150.047 79.941  1.00 69.27  ? 71  ARG A CZ  1 
ATOM   558   N NH1 . ARG A 1 125 ? 139.494 149.049 79.345  1.00 71.61  ? 71  ARG A NH1 1 
ATOM   559   N NH2 . ARG A 1 125 ? 138.730 150.036 81.264  1.00 65.20  ? 71  ARG A NH2 1 
ATOM   560   N N   . LEU A 1 126 ? 133.669 154.250 78.702  1.00 72.19  ? 72  LEU A N   1 
ATOM   561   C CA  . LEU A 1 126 ? 132.254 154.173 79.036  1.00 75.32  ? 72  LEU A CA  1 
ATOM   562   C C   . LEU A 1 126 ? 131.511 155.472 78.757  1.00 76.15  ? 72  LEU A C   1 
ATOM   563   O O   . LEU A 1 126 ? 130.343 155.599 79.137  1.00 77.46  ? 72  LEU A O   1 
ATOM   564   C CB  . LEU A 1 126 ? 132.086 153.779 80.504  1.00 70.16  ? 72  LEU A CB  1 
ATOM   565   C CG  . LEU A 1 126 ? 132.749 152.454 80.878  1.00 67.72  ? 72  LEU A CG  1 
ATOM   566   C CD1 . LEU A 1 126 ? 132.590 152.163 82.359  1.00 61.94  ? 72  LEU A CD1 1 
ATOM   567   C CD2 . LEU A 1 126 ? 132.170 151.327 80.042  1.00 70.77  ? 72  LEU A CD2 1 
ATOM   568   N N   . ALA A 1 127 ? 132.159 156.438 78.113  1.00 74.65  ? 73  ALA A N   1 
ATOM   569   C CA  . ALA A 1 127 ? 131.501 157.696 77.790  1.00 73.36  ? 73  ALA A CA  1 
ATOM   570   C C   . ALA A 1 127 ? 130.528 157.502 76.636  1.00 76.98  ? 73  ALA A C   1 
ATOM   571   O O   . ALA A 1 127 ? 130.864 156.880 75.624  1.00 76.69  ? 73  ALA A O   1 
ATOM   572   C CB  . ALA A 1 127 ? 132.537 158.761 77.439  1.00 70.55  ? 73  ALA A CB  1 
ATOM   573   N N   . TYR A 1 128 ? 129.321 158.040 76.787  1.00 77.82  ? 74  TYR A N   1 
ATOM   574   C CA  . TYR A 1 128 ? 128.284 157.925 75.774  1.00 81.45  ? 74  TYR A CA  1 
ATOM   575   C C   . TYR A 1 128 ? 127.751 159.307 75.427  1.00 87.72  ? 74  TYR A C   1 
ATOM   576   O O   . TYR A 1 128 ? 127.751 160.219 76.258  1.00 85.28  ? 74  TYR A O   1 
ATOM   577   C CB  . TYR A 1 128 ? 127.135 157.020 76.243  1.00 78.46  ? 74  TYR A CB  1 
ATOM   578   C CG  . TYR A 1 128 ? 126.476 157.470 77.527  1.00 74.45  ? 74  TYR A CG  1 
ATOM   579   C CD1 . TYR A 1 128 ? 126.963 157.063 78.760  1.00 73.06  ? 74  TYR A CD1 1 
ATOM   580   C CD2 . TYR A 1 128 ? 125.362 158.297 77.505  1.00 79.93  ? 74  TYR A CD2 1 
ATOM   581   C CE1 . TYR A 1 128 ? 126.363 157.470 79.935  1.00 73.34  ? 74  TYR A CE1 1 
ATOM   582   C CE2 . TYR A 1 128 ? 124.757 158.710 78.674  1.00 81.50  ? 74  TYR A CE2 1 
ATOM   583   C CZ  . TYR A 1 128 ? 125.261 158.293 79.886  1.00 78.19  ? 74  TYR A CZ  1 
ATOM   584   O OH  . TYR A 1 128 ? 124.658 158.702 81.052  1.00 78.23  ? 74  TYR A OH  1 
ATOM   585   N N   . SER A 1 129 ? 127.297 159.451 74.184  1.00 95.05  ? 75  SER A N   1 
ATOM   586   C CA  . SER A 1 129 ? 126.762 160.707 73.682  1.00 99.69  ? 75  SER A CA  1 
ATOM   587   C C   . SER A 1 129 ? 125.381 160.473 73.089  1.00 99.29  ? 75  SER A C   1 
ATOM   588   O O   . SER A 1 129 ? 125.158 159.485 72.383  1.00 98.11  ? 75  SER A O   1 
ATOM   589   C CB  . SER A 1 129 ? 127.688 161.323 72.626  1.00 103.92 ? 75  SER A CB  1 
ATOM   590   O OG  . SER A 1 129 ? 127.907 160.423 71.552  1.00 111.67 ? 75  SER A OG  1 
ATOM   591   N N   . GLY A 1 130 ? 124.458 161.386 73.378  1.00 98.12  ? 76  GLY A N   1 
ATOM   592   C CA  . GLY A 1 130 ? 123.101 161.313 72.876  1.00 101.96 ? 76  GLY A CA  1 
ATOM   593   C C   . GLY A 1 130 ? 122.049 161.044 73.928  1.00 103.85 ? 76  GLY A C   1 
ATOM   594   O O   . GLY A 1 130 ? 120.857 161.210 73.640  1.00 107.74 ? 76  GLY A O   1 
ATOM   595   N N   . ILE A 1 131 ? 122.440 160.637 75.129  1.00 99.97  ? 77  ILE A N   1 
ATOM   596   C CA  . ILE A 1 131 ? 121.512 160.362 76.219  1.00 100.81 ? 77  ILE A CA  1 
ATOM   597   C C   . ILE A 1 131 ? 121.737 161.416 77.301  1.00 104.91 ? 77  ILE A C   1 
ATOM   598   O O   . ILE A 1 131 ? 122.801 161.431 77.936  1.00 104.84 ? 77  ILE A O   1 
ATOM   599   C CB  . ILE A 1 131 ? 121.695 158.945 76.775  1.00 96.33  ? 77  ILE A CB  1 
ATOM   600   C CG1 . ILE A 1 131 ? 121.509 157.913 75.663  1.00 96.57  ? 77  ILE A CG1 1 
ATOM   601   C CG2 . ILE A 1 131 ? 120.723 158.693 77.916  1.00 93.43  ? 77  ILE A CG2 1 
ATOM   602   C CD1 . ILE A 1 131 ? 121.704 156.486 76.117  1.00 93.91  ? 77  ILE A CD1 1 
ATOM   603   N N   . PRO A 1 132 ? 120.777 162.314 77.547  1.00 104.85 ? 78  PRO A N   1 
ATOM   604   C CA  . PRO A 1 132 ? 120.909 163.327 78.601  1.00 101.09 ? 78  PRO A CA  1 
ATOM   605   C C   . PRO A 1 132 ? 120.482 162.825 79.980  1.00 97.76  ? 78  PRO A C   1 
ATOM   606   O O   . PRO A 1 132 ? 119.711 163.475 80.687  1.00 100.47 ? 78  PRO A O   1 
ATOM   607   C CB  . PRO A 1 132 ? 119.994 164.448 78.102  1.00 100.72 ? 78  PRO A CB  1 
ATOM   608   C CG  . PRO A 1 132 ? 118.908 163.718 77.385  1.00 104.99 ? 78  PRO A CG  1 
ATOM   609   C CD  . PRO A 1 132 ? 119.552 162.506 76.751  1.00 104.81 ? 78  PRO A CD  1 
ATOM   610   N N   . LEU A 1 133 ? 120.990 161.657 80.365  1.00 92.98  ? 79  LEU A N   1 
ATOM   611   C CA  . LEU A 1 133 ? 120.612 161.032 81.622  1.00 91.43  ? 79  LEU A CA  1 
ATOM   612   C C   . LEU A 1 133 ? 121.813 160.314 82.218  1.00 84.43  ? 79  LEU A C   1 
ATOM   613   O O   . LEU A 1 133 ? 122.762 159.955 81.517  1.00 84.02  ? 79  LEU A O   1 
ATOM   614   C CB  . LEU A 1 133 ? 119.454 160.038 81.440  1.00 96.80  ? 79  LEU A CB  1 
ATOM   615   C CG  . LEU A 1 133 ? 118.078 160.582 81.048  1.00 101.06 ? 79  LEU A CG  1 
ATOM   616   C CD1 . LEU A 1 133 ? 117.113 159.440 80.766  1.00 100.18 ? 79  LEU A CD1 1 
ATOM   617   C CD2 . LEU A 1 133 ? 117.530 161.489 82.136  1.00 98.61  ? 79  LEU A CD2 1 
ATOM   618   N N   . ASN A 1 134 ? 121.756 160.112 83.531  1.00 82.93  ? 80  ASN A N   1 
ATOM   619   C CA  . ASN A 1 134 ? 122.735 159.296 84.240  1.00 77.47  ? 80  ASN A CA  1 
ATOM   620   C C   . ASN A 1 134 ? 122.219 157.864 84.258  1.00 75.34  ? 80  ASN A C   1 
ATOM   621   O O   . ASN A 1 134 ? 121.192 157.574 84.879  1.00 79.84  ? 80  ASN A O   1 
ATOM   622   C CB  . ASN A 1 134 ? 122.957 159.825 85.653  1.00 76.18  ? 80  ASN A CB  1 
ATOM   623   C CG  . ASN A 1 134 ? 123.692 161.146 85.670  1.00 78.35  ? 80  ASN A CG  1 
ATOM   624   O OD1 . ASN A 1 134 ? 124.735 161.298 85.035  1.00 77.24  ? 80  ASN A OD1 1 
ATOM   625   N ND2 . ASN A 1 134 ? 123.150 162.112 86.397  1.00 88.27  ? 80  ASN A ND2 1 
ATOM   626   N N   . LEU A 1 135 ? 122.928 156.968 83.579  1.00 67.90  ? 81  LEU A N   1 
ATOM   627   C CA  . LEU A 1 135 ? 122.446 155.603 83.385  1.00 64.69  ? 81  LEU A CA  1 
ATOM   628   C C   . LEU A 1 135 ? 122.780 154.782 84.622  1.00 61.06  ? 81  LEU A C   1 
ATOM   629   O O   . LEU A 1 135 ? 123.923 154.374 84.821  1.00 63.72  ? 81  LEU A O   1 
ATOM   630   C CB  . LEU A 1 135 ? 123.061 154.991 82.132  1.00 66.38  ? 81  LEU A CB  1 
ATOM   631   C CG  . LEU A 1 135 ? 122.843 155.761 80.828  1.00 71.35  ? 81  LEU A CG  1 
ATOM   632   C CD1 . LEU A 1 135 ? 123.391 154.982 79.644  1.00 69.89  ? 81  LEU A CD1 1 
ATOM   633   C CD2 . LEU A 1 135 ? 121.371 156.075 80.629  1.00 77.65  ? 81  LEU A CD2 1 
ATOM   634   N N   . THR A 1 136 ? 121.783 154.551 85.470  1.00 59.65  ? 82  THR A N   1 
ATOM   635   C CA  . THR A 1 136 ? 121.945 153.647 86.601  1.00 57.57  ? 82  THR A CA  1 
ATOM   636   C C   . THR A 1 136 ? 121.666 152.233 86.114  1.00 57.30  ? 82  THR A C   1 
ATOM   637   O O   . THR A 1 136 ? 120.537 151.917 85.726  1.00 64.72  ? 82  THR A O   1 
ATOM   638   C CB  . THR A 1 136 ? 121.007 154.031 87.741  1.00 63.70  ? 82  THR A CB  1 
ATOM   639   O OG1 . THR A 1 136 ? 121.273 155.378 88.148  1.00 69.32  ? 82  THR A OG1 1 
ATOM   640   C CG2 . THR A 1 136 ? 121.209 153.099 88.921  1.00 62.72  ? 82  THR A CG2 1 
ATOM   641   N N   . LEU A 1 137 ? 122.683 151.382 86.127  1.00 57.60  ? 83  LEU A N   1 
ATOM   642   C CA  . LEU A 1 137 ? 122.557 150.056 85.544  1.00 58.79  ? 83  LEU A CA  1 
ATOM   643   C C   . LEU A 1 137 ? 122.377 149.000 86.625  1.00 64.05  ? 83  LEU A C   1 
ATOM   644   O O   . LEU A 1 137 ? 122.726 149.201 87.791  1.00 64.70  ? 83  LEU A O   1 
ATOM   645   C CB  . LEU A 1 137 ? 123.779 149.722 84.685  1.00 58.38  ? 83  LEU A CB  1 
ATOM   646   C CG  . LEU A 1 137 ? 123.995 150.572 83.434  1.00 56.55  ? 83  LEU A CG  1 
ATOM   647   C CD1 . LEU A 1 137 ? 125.178 150.050 82.638  1.00 57.04  ? 83  LEU A CD1 1 
ATOM   648   C CD2 . LEU A 1 137 ? 122.743 150.592 82.578  1.00 55.76  ? 83  LEU A CD2 1 
ATOM   649   N N   . ASP A 1 138 ? 121.811 147.866 86.217  1.00 62.99  ? 84  ASP A N   1 
ATOM   650   C CA  . ASP A 1 138 ? 121.649 146.738 87.122  1.00 64.93  ? 84  ASP A CA  1 
ATOM   651   C C   . ASP A 1 138 ? 123.005 146.311 87.667  1.00 67.06  ? 84  ASP A C   1 
ATOM   652   O O   . ASP A 1 138 ? 124.010 146.326 86.953  1.00 71.25  ? 84  ASP A O   1 
ATOM   653   C CB  . ASP A 1 138 ? 120.975 145.575 86.396  1.00 62.02  ? 84  ASP A CB  1 
ATOM   654   C CG  . ASP A 1 138 ? 120.506 144.492 87.340  1.00 71.09  ? 84  ASP A CG  1 
ATOM   655   O OD1 . ASP A 1 138 ? 120.432 144.753 88.558  1.00 75.29  ? 84  ASP A OD1 1 
ATOM   656   O OD2 . ASP A 1 138 ? 120.214 143.375 86.865  1.00 75.99  ? 84  ASP A OD2 1 
ATOM   657   N N   . ASN A 1 139 ? 123.029 145.930 88.947  1.00 63.65  ? 85  ASN A N   1 
ATOM   658   C CA  . ASN A 1 139 ? 124.296 145.673 89.627  1.00 63.57  ? 85  ASN A CA  1 
ATOM   659   C C   . ASN A 1 139 ? 125.107 144.578 88.945  1.00 67.70  ? 85  ASN A C   1 
ATOM   660   O O   . ASN A 1 139 ? 126.340 144.571 89.040  1.00 69.30  ? 85  ASN A O   1 
ATOM   661   C CB  . ASN A 1 139 ? 124.040 145.305 91.089  1.00 58.78  ? 85  ASN A CB  1 
ATOM   662   C CG  . ASN A 1 139 ? 123.316 143.984 91.241  1.00 63.04  ? 85  ASN A CG  1 
ATOM   663   O OD1 . ASN A 1 139 ? 123.940 142.927 91.325  1.00 66.25  ? 85  ASN A OD1 1 
ATOM   664   N ND2 . ASN A 1 139 ? 121.990 144.037 91.284  1.00 66.76  ? 85  ASN A ND2 1 
ATOM   665   N N   . ARG A 1 140 ? 124.442 143.654 88.246  1.00 68.83  ? 86  ARG A N   1 
ATOM   666   C CA  . ARG A 1 140 ? 125.158 142.562 87.595  1.00 68.21  ? 86  ARG A CA  1 
ATOM   667   C C   . ARG A 1 140 ? 126.127 143.072 86.537  1.00 69.30  ? 86  ARG A C   1 
ATOM   668   O O   . ARG A 1 140 ? 127.161 142.439 86.287  1.00 72.64  ? 86  ARG A O   1 
ATOM   669   C CB  . ARG A 1 140 ? 124.159 141.577 86.989  1.00 68.79  ? 86  ARG A CB  1 
ATOM   670   C CG  . ARG A 1 140 ? 123.434 140.748 88.034  1.00 74.00  ? 86  ARG A CG  1 
ATOM   671   C CD  . ARG A 1 140 ? 122.296 139.943 87.440  1.00 76.81  ? 86  ARG A CD  1 
ATOM   672   N NE  . ARG A 1 140 ? 121.101 140.753 87.242  1.00 78.53  ? 86  ARG A NE  1 
ATOM   673   C CZ  . ARG A 1 140 ? 119.908 140.261 86.940  1.00 80.37  ? 86  ARG A CZ  1 
ATOM   674   N NH1 . ARG A 1 140 ? 119.714 138.961 86.789  1.00 82.24  ? 86  ARG A NH1 1 
ATOM   675   N NH2 . ARG A 1 140 ? 118.882 141.095 86.790  1.00 83.48  ? 86  ARG A NH2 1 
ATOM   676   N N   . VAL A 1 141 ? 125.829 144.222 85.926  1.00 66.94  ? 87  VAL A N   1 
ATOM   677   C CA  . VAL A 1 141 ? 126.728 144.806 84.939  1.00 67.04  ? 87  VAL A CA  1 
ATOM   678   C C   . VAL A 1 141 ? 128.086 145.131 85.542  1.00 69.34  ? 87  VAL A C   1 
ATOM   679   O O   . VAL A 1 141 ? 129.062 145.309 84.806  1.00 67.85  ? 87  VAL A O   1 
ATOM   680   C CB  . VAL A 1 141 ? 126.100 146.066 84.307  1.00 60.28  ? 87  VAL A CB  1 
ATOM   681   C CG1 . VAL A 1 141 ? 126.390 147.291 85.156  1.00 60.03  ? 87  VAL A CG1 1 
ATOM   682   C CG2 . VAL A 1 141 ? 126.618 146.265 82.894  1.00 62.35  ? 87  VAL A CG2 1 
ATOM   683   N N   . ALA A 1 142 ? 128.176 145.215 86.873  1.00 68.88  ? 88  ALA A N   1 
ATOM   684   C CA  . ALA A 1 142 ? 129.463 145.447 87.514  1.00 66.99  ? 88  ALA A CA  1 
ATOM   685   C C   . ALA A 1 142 ? 130.446 144.319 87.244  1.00 70.20  ? 88  ALA A C   1 
ATOM   686   O O   . ALA A 1 142 ? 131.658 144.521 87.381  1.00 70.75  ? 88  ALA A O   1 
ATOM   687   C CB  . ALA A 1 142 ? 129.277 145.631 89.020  1.00 60.30  ? 88  ALA A CB  1 
ATOM   688   N N   . ASP A 1 143 ? 129.957 143.137 86.866  1.00 72.33  ? 89  ASP A N   1 
ATOM   689   C CA  . ASP A 1 143 ? 130.841 142.042 86.497  1.00 74.08  ? 89  ASP A CA  1 
ATOM   690   C C   . ASP A 1 143 ? 131.475 142.232 85.126  1.00 75.91  ? 89  ASP A C   1 
ATOM   691   O O   . ASP A 1 143 ? 132.386 141.475 84.773  1.00 77.22  ? 89  ASP A O   1 
ATOM   692   C CB  . ASP A 1 143 ? 130.077 140.717 86.527  1.00 77.33  ? 89  ASP A CB  1 
ATOM   693   C CG  . ASP A 1 143 ? 129.546 140.382 87.904  1.00 85.33  ? 89  ASP A CG  1 
ATOM   694   O OD1 . ASP A 1 143 ? 130.207 140.744 88.900  1.00 82.46  ? 89  ASP A OD1 1 
ATOM   695   O OD2 . ASP A 1 143 ? 128.468 139.757 87.993  1.00 91.62  ? 89  ASP A OD2 1 
ATOM   696   N N   . GLN A 1 144 ? 131.023 143.218 84.354  1.00 73.17  ? 90  GLN A N   1 
ATOM   697   C CA  . GLN A 1 144 ? 131.506 143.443 83.001  1.00 68.17  ? 90  GLN A CA  1 
ATOM   698   C C   . GLN A 1 144 ? 132.372 144.688 82.874  1.00 67.79  ? 90  GLN A C   1 
ATOM   699   O O   . GLN A 1 144 ? 132.813 145.007 81.766  1.00 67.91  ? 90  GLN A O   1 
ATOM   700   C CB  . GLN A 1 144 ? 130.320 143.540 82.036  1.00 66.31  ? 90  GLN A CB  1 
ATOM   701   C CG  . GLN A 1 144 ? 129.275 142.458 82.246  1.00 67.22  ? 90  GLN A CG  1 
ATOM   702   C CD  . GLN A 1 144 ? 128.018 142.700 81.439  1.00 75.79  ? 90  GLN A CD  1 
ATOM   703   O OE1 . GLN A 1 144 ? 128.050 143.370 80.408  1.00 81.21  ? 90  GLN A OE1 1 
ATOM   704   N NE2 . GLN A 1 144 ? 126.900 142.159 81.907  1.00 72.42  ? 90  GLN A NE2 1 
ATOM   705   N N   . LEU A 1 145 ? 132.626 145.397 83.969  1.00 66.52  ? 91  LEU A N   1 
ATOM   706   C CA  . LEU A 1 145 ? 133.399 146.627 83.952  1.00 63.00  ? 91  LEU A CA  1 
ATOM   707   C C   . LEU A 1 145 ? 134.666 146.461 84.779  1.00 63.52  ? 91  LEU A C   1 
ATOM   708   O O   . LEU A 1 145 ? 134.800 145.525 85.570  1.00 65.73  ? 91  LEU A O   1 
ATOM   709   C CB  . LEU A 1 145 ? 132.586 147.806 84.500  1.00 58.13  ? 91  LEU A CB  1 
ATOM   710   C CG  . LEU A 1 145 ? 131.248 148.113 83.831  1.00 57.23  ? 91  LEU A CG  1 
ATOM   711   C CD1 . LEU A 1 145 ? 130.513 149.191 84.603  1.00 54.23  ? 91  LEU A CD1 1 
ATOM   712   C CD2 . LEU A 1 145 ? 131.465 148.543 82.396  1.00 59.94  ? 91  LEU A CD2 1 
ATOM   713   N N   . TRP A 1 146 ? 135.600 147.386 84.583  1.00 60.19  ? 92  TRP A N   1 
ATOM   714   C CA  . TRP A 1 146 ? 136.782 147.454 85.428  1.00 54.34  ? 92  TRP A CA  1 
ATOM   715   C C   . TRP A 1 146 ? 136.437 148.179 86.720  1.00 56.15  ? 92  TRP A C   1 
ATOM   716   O O   . TRP A 1 146 ? 135.844 149.261 86.694  1.00 59.41  ? 92  TRP A O   1 
ATOM   717   C CB  . TRP A 1 146 ? 137.921 148.174 84.711  1.00 51.76  ? 92  TRP A CB  1 
ATOM   718   C CG  . TRP A 1 146 ? 139.165 148.306 85.542  1.00 51.74  ? 92  TRP A CG  1 
ATOM   719   C CD1 . TRP A 1 146 ? 140.240 147.469 85.539  1.00 55.46  ? 92  TRP A CD1 1 
ATOM   720   C CD2 . TRP A 1 146 ? 139.462 149.335 86.496  1.00 52.60  ? 92  TRP A CD2 1 
ATOM   721   N NE1 . TRP A 1 146 ? 141.188 147.911 86.430  1.00 55.96  ? 92  TRP A NE1 1 
ATOM   722   C CE2 . TRP A 1 146 ? 140.733 149.055 87.030  1.00 55.81  ? 92  TRP A CE2 1 
ATOM   723   C CE3 . TRP A 1 146 ? 138.774 150.464 86.950  1.00 52.09  ? 92  TRP A CE3 1 
ATOM   724   C CZ2 . TRP A 1 146 ? 141.332 149.862 87.994  1.00 54.85  ? 92  TRP A CZ2 1 
ATOM   725   C CZ3 . TRP A 1 146 ? 139.370 151.263 87.906  1.00 51.98  ? 92  TRP A CZ3 1 
ATOM   726   C CH2 . TRP A 1 146 ? 140.636 150.959 88.417  1.00 51.69  ? 92  TRP A CH2 1 
ATOM   727   N N   . VAL A 1 147 ? 136.809 147.586 87.847  1.00 55.34  ? 93  VAL A N   1 
ATOM   728   C CA  . VAL A 1 147 ? 136.601 148.219 89.145  1.00 52.54  ? 93  VAL A CA  1 
ATOM   729   C C   . VAL A 1 147 ? 137.925 148.194 89.899  1.00 55.01  ? 93  VAL A C   1 
ATOM   730   O O   . VAL A 1 147 ? 138.735 147.280 89.690  1.00 57.36  ? 93  VAL A O   1 
ATOM   731   C CB  . VAL A 1 147 ? 135.484 147.522 89.937  1.00 52.18  ? 93  VAL A CB  1 
ATOM   732   C CG1 . VAL A 1 147 ? 134.143 147.743 89.263  1.00 50.34  ? 93  VAL A CG1 1 
ATOM   733   C CG2 . VAL A 1 147 ? 135.775 146.039 90.059  1.00 59.74  ? 93  VAL A CG2 1 
ATOM   734   N N   . PRO A 1 148 ? 138.198 149.170 90.761  1.00 51.61  ? 94  PRO A N   1 
ATOM   735   C CA  . PRO A 1 148 ? 139.466 149.167 91.493  1.00 50.78  ? 94  PRO A CA  1 
ATOM   736   C C   . PRO A 1 148 ? 139.565 147.975 92.430  1.00 54.20  ? 94  PRO A C   1 
ATOM   737   O O   . PRO A 1 148 ? 138.568 147.493 92.973  1.00 57.71  ? 94  PRO A O   1 
ATOM   738   C CB  . PRO A 1 148 ? 139.430 150.484 92.276  1.00 48.31  ? 94  PRO A CB  1 
ATOM   739   C CG  . PRO A 1 148 ? 138.443 151.333 91.555  1.00 50.24  ? 94  PRO A CG  1 
ATOM   740   C CD  . PRO A 1 148 ? 137.415 150.387 91.023  1.00 50.54  ? 94  PRO A CD  1 
ATOM   741   N N   . ASP A 1 149 ? 140.793 147.500 92.614  1.00 51.52  ? 95  ASP A N   1 
ATOM   742   C CA  . ASP A 1 149 ? 141.067 146.405 93.542  1.00 49.11  ? 95  ASP A CA  1 
ATOM   743   C C   . ASP A 1 149 ? 141.258 146.930 94.960  1.00 49.89  ? 95  ASP A C   1 
ATOM   744   O O   . ASP A 1 149 ? 142.245 146.651 95.637  1.00 53.09  ? 95  ASP A O   1 
ATOM   745   C CB  . ASP A 1 149 ? 142.284 145.618 93.074  1.00 57.69  ? 95  ASP A CB  1 
ATOM   746   C CG  . ASP A 1 149 ? 143.525 146.475 92.969  1.00 60.69  ? 95  ASP A CG  1 
ATOM   747   O OD1 . ASP A 1 149 ? 143.386 147.711 92.853  1.00 60.34  ? 95  ASP A OD1 1 
ATOM   748   O OD2 . ASP A 1 149 ? 144.639 145.913 92.999  1.00 58.47  ? 95  ASP A OD2 1 
ATOM   749   N N   . THR A 1 150 ? 140.280 147.706 95.413  1.00 46.10  ? 96  THR A N   1 
ATOM   750   C CA  . THR A 1 150 ? 140.353 148.357 96.711  1.00 41.66  ? 96  THR A CA  1 
ATOM   751   C C   . THR A 1 150 ? 140.009 147.369 97.815  1.00 44.01  ? 96  THR A C   1 
ATOM   752   O O   . THR A 1 150 ? 138.975 146.698 97.761  1.00 52.63  ? 96  THR A O   1 
ATOM   753   C CB  . THR A 1 150 ? 139.402 149.551 96.746  1.00 41.83  ? 96  THR A CB  1 
ATOM   754   O OG1 . THR A 1 150 ? 139.976 150.640 96.014  1.00 48.00  ? 96  THR A OG1 1 
ATOM   755   C CG2 . THR A 1 150 ? 139.134 149.982 98.170  1.00 41.51  ? 96  THR A CG2 1 
ATOM   756   N N   . TYR A 1 151 ? 140.881 147.279 98.816  1.00 37.95  ? 97  TYR A N   1 
ATOM   757   C CA  . TYR A 1 151 ? 140.678 146.394 99.949  1.00 38.31  ? 97  TYR A CA  1 
ATOM   758   C C   . TYR A 1 151 ? 140.958 147.153 101.238 1.00 40.39  ? 97  TYR A C   1 
ATOM   759   O O   . TYR A 1 151 ? 141.511 148.258 101.235 1.00 44.65  ? 97  TYR A O   1 
ATOM   760   C CB  . TYR A 1 151 ? 141.562 145.142 99.855  1.00 39.07  ? 97  TYR A CB  1 
ATOM   761   C CG  . TYR A 1 151 ? 143.018 145.375 100.180 1.00 40.23  ? 97  TYR A CG  1 
ATOM   762   C CD1 . TYR A 1 151 ? 143.834 146.091 99.319  1.00 41.35  ? 97  TYR A CD1 1 
ATOM   763   C CD2 . TYR A 1 151 ? 143.582 144.864 101.339 1.00 41.93  ? 97  TYR A CD2 1 
ATOM   764   C CE1 . TYR A 1 151 ? 145.163 146.305 99.612  1.00 42.72  ? 97  TYR A CE1 1 
ATOM   765   C CE2 . TYR A 1 151 ? 144.912 145.070 101.636 1.00 43.71  ? 97  TYR A CE2 1 
ATOM   766   C CZ  . TYR A 1 151 ? 145.697 145.790 100.767 1.00 45.24  ? 97  TYR A CZ  1 
ATOM   767   O OH  . TYR A 1 151 ? 147.025 146.001 101.052 1.00 51.27  ? 97  TYR A OH  1 
ATOM   768   N N   . PHE A 1 152 ? 140.548 146.551 102.349 1.00 36.86  ? 98  PHE A N   1 
ATOM   769   C CA  . PHE A 1 152 ? 140.744 147.126 103.671 1.00 32.99  ? 98  PHE A CA  1 
ATOM   770   C C   . PHE A 1 152 ? 141.908 146.413 104.341 1.00 39.04  ? 98  PHE A C   1 
ATOM   771   O O   . PHE A 1 152 ? 141.880 145.190 104.508 1.00 47.91  ? 98  PHE A O   1 
ATOM   772   C CB  . PHE A 1 152 ? 139.471 147.023 104.506 1.00 36.93  ? 98  PHE A CB  1 
ATOM   773   C CG  . PHE A 1 152 ? 138.275 147.634 103.843 1.00 37.60  ? 98  PHE A CG  1 
ATOM   774   C CD1 . PHE A 1 152 ? 138.258 148.982 103.533 1.00 36.28  ? 98  PHE A CD1 1 
ATOM   775   C CD2 . PHE A 1 152 ? 137.177 146.864 103.519 1.00 40.59  ? 98  PHE A CD2 1 
ATOM   776   C CE1 . PHE A 1 152 ? 137.167 149.550 102.916 1.00 34.95  ? 98  PHE A CE1 1 
ATOM   777   C CE2 . PHE A 1 152 ? 136.081 147.428 102.903 1.00 39.05  ? 98  PHE A CE2 1 
ATOM   778   C CZ  . PHE A 1 152 ? 136.078 148.772 102.600 1.00 37.59  ? 98  PHE A CZ  1 
ATOM   779   N N   . LEU A 1 153 ? 142.928 147.184 104.717 1.00 38.95  ? 99  LEU A N   1 
ATOM   780   C CA  . LEU A 1 153 ? 144.197 146.601 105.134 1.00 40.60  ? 99  LEU A CA  1 
ATOM   781   C C   . LEU A 1 153 ? 144.061 145.797 106.421 1.00 41.53  ? 99  LEU A C   1 
ATOM   782   O O   . LEU A 1 153 ? 144.638 144.712 106.547 1.00 48.02  ? 99  LEU A O   1 
ATOM   783   C CB  . LEU A 1 153 ? 145.233 147.708 105.304 1.00 43.48  ? 99  LEU A CB  1 
ATOM   784   C CG  . LEU A 1 153 ? 146.696 147.299 105.431 1.00 51.47  ? 99  LEU A CG  1 
ATOM   785   C CD1 . LEU A 1 153 ? 147.307 147.138 104.057 1.00 54.18  ? 99  LEU A CD1 1 
ATOM   786   C CD2 . LEU A 1 153 ? 147.456 148.327 106.243 1.00 58.91  ? 99  LEU A CD2 1 
ATOM   787   N N   . ASN A 1 154 ? 143.305 146.309 107.389 1.00 39.52  ? 100 ASN A N   1 
ATOM   788   C CA  . ASN A 1 154 ? 143.269 145.750 108.736 1.00 42.06  ? 100 ASN A CA  1 
ATOM   789   C C   . ASN A 1 154 ? 141.932 145.089 109.057 1.00 46.96  ? 100 ASN A C   1 
ATOM   790   O O   . ASN A 1 154 ? 141.435 145.181 110.180 1.00 53.62  ? 100 ASN A O   1 
ATOM   791   C CB  . ASN A 1 154 ? 143.585 146.828 109.769 1.00 44.69  ? 100 ASN A CB  1 
ATOM   792   C CG  . ASN A 1 154 ? 142.591 147.970 109.740 1.00 48.73  ? 100 ASN A CG  1 
ATOM   793   O OD1 . ASN A 1 154 ? 142.017 148.282 108.697 1.00 48.87  ? 100 ASN A OD1 1 
ATOM   794   N ND2 . ASN A 1 154 ? 142.382 148.601 110.887 1.00 51.03  ? 100 ASN A ND2 1 
ATOM   795   N N   . ASP A 1 155 ? 141.335 144.411 108.084 1.00 45.67  ? 101 ASP A N   1 
ATOM   796   C CA  . ASP A 1 155 ? 140.095 143.685 108.310 1.00 46.54  ? 101 ASP A CA  1 
ATOM   797   C C   . ASP A 1 155 ? 140.382 142.209 108.557 1.00 48.66  ? 101 ASP A C   1 
ATOM   798   O O   . ASP A 1 155 ? 141.454 141.694 108.232 1.00 54.13  ? 101 ASP A O   1 
ATOM   799   C CB  . ASP A 1 155 ? 139.139 143.842 107.125 1.00 48.29  ? 101 ASP A CB  1 
ATOM   800   C CG  . ASP A 1 155 ? 139.584 143.060 105.908 1.00 55.30  ? 101 ASP A CG  1 
ATOM   801   O OD1 . ASP A 1 155 ? 140.806 142.933 105.694 1.00 59.00  ? 101 ASP A OD1 1 
ATOM   802   O OD2 . ASP A 1 155 ? 138.710 142.568 105.164 1.00 58.61  ? 101 ASP A OD2 1 
ATOM   803   N N   . LYS A 1 156 ? 139.398 141.530 109.134 1.00 48.11  ? 102 LYS A N   1 
ATOM   804   C CA  . LYS A 1 156 ? 139.487 140.113 109.448 1.00 49.08  ? 102 LYS A CA  1 
ATOM   805   C C   . LYS A 1 156 ? 138.382 139.299 108.804 1.00 50.62  ? 102 LYS A C   1 
ATOM   806   O O   . LYS A 1 156 ? 138.610 138.151 108.416 1.00 61.28  ? 102 LYS A O   1 
ATOM   807   C CB  . LYS A 1 156 ? 139.450 139.919 110.970 1.00 47.15  ? 102 LYS A CB  1 
ATOM   808   C CG  . LYS A 1 156 ? 140.423 140.817 111.712 1.00 48.42  ? 102 LYS A CG  1 
ATOM   809   C CD  . LYS A 1 156 ? 140.139 140.854 113.201 1.00 50.07  ? 102 LYS A CD  1 
ATOM   810   C CE  . LYS A 1 156 ? 140.351 139.498 113.843 1.00 48.64  ? 102 LYS A CE  1 
ATOM   811   N NZ  . LYS A 1 156 ? 140.110 139.553 115.309 1.00 50.19  ? 102 LYS A NZ  1 
ATOM   812   N N   . LYS A 1 157 ? 137.185 139.868 108.682 1.00 46.04  ? 103 LYS A N   1 
ATOM   813   C CA  . LYS A 1 157 ? 136.079 139.195 108.012 1.00 47.80  ? 103 LYS A CA  1 
ATOM   814   C C   . LYS A 1 157 ? 135.125 140.271 107.516 1.00 51.74  ? 103 LYS A C   1 
ATOM   815   O O   . LYS A 1 157 ? 134.460 140.924 108.325 1.00 56.97  ? 103 LYS A O   1 
ATOM   816   C CB  . LYS A 1 157 ? 135.378 138.224 108.951 1.00 48.80  ? 103 LYS A CB  1 
ATOM   817   C CG  . LYS A 1 157 ? 135.467 136.777 108.510 1.00 55.98  ? 103 LYS A CG  1 
ATOM   818   C CD  . LYS A 1 157 ? 135.013 136.620 107.070 1.00 52.71  ? 103 LYS A CD  1 
ATOM   819   C CE  . LYS A 1 157 ? 135.184 135.190 106.591 1.00 50.20  ? 103 LYS A CE  1 
ATOM   820   N NZ  . LYS A 1 157 ? 134.839 135.039 105.151 1.00 52.03  ? 103 LYS A NZ  1 
ATOM   821   N N   . SER A 1 158 ? 135.064 140.454 106.201 1.00 45.84  ? 104 SER A N   1 
ATOM   822   C CA  . SER A 1 158 ? 134.200 141.450 105.589 1.00 40.75  ? 104 SER A CA  1 
ATOM   823   C C   . SER A 1 158 ? 133.452 140.822 104.424 1.00 41.32  ? 104 SER A C   1 
ATOM   824   O O   . SER A 1 158 ? 133.925 139.865 103.807 1.00 48.84  ? 104 SER A O   1 
ATOM   825   C CB  . SER A 1 158 ? 135.000 142.666 105.108 1.00 41.16  ? 104 SER A CB  1 
ATOM   826   O OG  . SER A 1 158 ? 136.075 142.268 104.278 1.00 51.91  ? 104 SER A OG  1 
ATOM   827   N N   . PHE A 1 159 ? 132.277 141.371 104.127 1.00 37.44  ? 105 PHE A N   1 
ATOM   828   C CA  . PHE A 1 159 ? 131.445 140.834 103.062 1.00 38.93  ? 105 PHE A CA  1 
ATOM   829   C C   . PHE A 1 159 ? 130.520 141.923 102.543 1.00 39.20  ? 105 PHE A C   1 
ATOM   830   O O   . PHE A 1 159 ? 130.294 142.942 103.199 1.00 42.99  ? 105 PHE A O   1 
ATOM   831   C CB  . PHE A 1 159 ? 130.631 139.627 103.539 1.00 39.09  ? 105 PHE A CB  1 
ATOM   832   C CG  . PHE A 1 159 ? 129.609 139.961 104.586 1.00 38.89  ? 105 PHE A CG  1 
ATOM   833   C CD1 . PHE A 1 159 ? 129.967 140.049 105.920 1.00 39.87  ? 105 PHE A CD1 1 
ATOM   834   C CD2 . PHE A 1 159 ? 128.289 140.178 104.236 1.00 39.54  ? 105 PHE A CD2 1 
ATOM   835   C CE1 . PHE A 1 159 ? 129.028 140.353 106.883 1.00 40.14  ? 105 PHE A CE1 1 
ATOM   836   C CE2 . PHE A 1 159 ? 127.346 140.483 105.195 1.00 40.99  ? 105 PHE A CE2 1 
ATOM   837   C CZ  . PHE A 1 159 ? 127.716 140.571 106.521 1.00 40.32  ? 105 PHE A CZ  1 
ATOM   838   N N   . VAL A 1 160 ? 129.985 141.688 101.350 1.00 36.13  ? 106 VAL A N   1 
ATOM   839   C CA  . VAL A 1 160 ? 128.998 142.565 100.734 1.00 33.52  ? 106 VAL A CA  1 
ATOM   840   C C   . VAL A 1 160 ? 127.636 141.899 100.848 1.00 39.65  ? 106 VAL A C   1 
ATOM   841   O O   . VAL A 1 160 ? 127.467 140.742 100.442 1.00 46.27  ? 106 VAL A O   1 
ATOM   842   C CB  . VAL A 1 160 ? 129.350 142.859 99.267  1.00 34.54  ? 106 VAL A CB  1 
ATOM   843   C CG1 . VAL A 1 160 ? 128.302 143.762 98.641  1.00 35.78  ? 106 VAL A CG1 1 
ATOM   844   C CG2 . VAL A 1 160 ? 130.724 143.495 99.176  1.00 33.83  ? 106 VAL A CG2 1 
ATOM   845   N N   . HIS A 1 161 ? 126.668 142.623 101.403 1.00 34.31  ? 107 HIS A N   1 
ATOM   846   C CA  . HIS A 1 161 ? 125.344 142.062 101.628 1.00 39.39  ? 107 HIS A CA  1 
ATOM   847   C C   . HIS A 1 161 ? 124.685 141.693 100.303 1.00 41.10  ? 107 HIS A C   1 
ATOM   848   O O   . HIS A 1 161 ? 124.926 142.320 99.269  1.00 44.00  ? 107 HIS A O   1 
ATOM   849   C CB  . HIS A 1 161 ? 124.472 143.055 102.394 1.00 38.03  ? 107 HIS A CB  1 
ATOM   850   C CG  . HIS A 1 161 ? 125.040 143.472 103.715 1.00 38.71  ? 107 HIS A CG  1 
ATOM   851   N ND1 . HIS A 1 161 ? 124.367 143.289 104.903 1.00 41.19  ? 107 HIS A ND1 1 
ATOM   852   C CD2 . HIS A 1 161 ? 126.213 144.066 104.036 1.00 39.35  ? 107 HIS A CD2 1 
ATOM   853   C CE1 . HIS A 1 161 ? 125.101 143.750 105.899 1.00 38.41  ? 107 HIS A CE1 1 
ATOM   854   N NE2 . HIS A 1 161 ? 126.227 144.226 105.400 1.00 38.71  ? 107 HIS A NE2 1 
ATOM   855   N N   . GLY A 1 162 ? 123.844 140.661 100.341 1.00 37.17  ? 108 GLY A N   1 
ATOM   856   C CA  . GLY A 1 162 ? 123.257 140.137 99.124  1.00 39.50  ? 108 GLY A CA  1 
ATOM   857   C C   . GLY A 1 162 ? 121.776 139.826 99.192  1.00 42.54  ? 108 GLY A C   1 
ATOM   858   O O   . GLY A 1 162 ? 121.306 138.902 98.522  1.00 46.72  ? 108 GLY A O   1 
ATOM   859   N N   . VAL A 1 163 ? 121.028 140.580 99.993  1.00 40.84  ? 109 VAL A N   1 
ATOM   860   C CA  . VAL A 1 163 ? 119.581 140.431 100.101 1.00 36.07  ? 109 VAL A CA  1 
ATOM   861   C C   . VAL A 1 163 ? 118.938 141.782 99.821  1.00 40.80  ? 109 VAL A C   1 
ATOM   862   O O   . VAL A 1 163 ? 119.294 142.782 100.453 1.00 45.81  ? 109 VAL A O   1 
ATOM   863   C CB  . VAL A 1 163 ? 119.166 139.904 101.488 1.00 34.01  ? 109 VAL A CB  1 
ATOM   864   C CG1 . VAL A 1 163 ? 117.665 140.004 101.676 1.00 36.58  ? 109 VAL A CG1 1 
ATOM   865   C CG2 . VAL A 1 163 ? 119.622 138.471 101.657 1.00 37.06  ? 109 VAL A CG2 1 
ATOM   866   N N   . THR A 1 164 ? 117.991 141.814 98.885  1.00 39.25  ? 110 THR A N   1 
ATOM   867   C CA  . THR A 1 164 ? 117.528 140.630 98.166  1.00 39.89  ? 110 THR A CA  1 
ATOM   868   C C   . THR A 1 164 ? 118.394 140.362 96.944  1.00 44.12  ? 110 THR A C   1 
ATOM   869   O O   . THR A 1 164 ? 118.283 139.320 96.301  1.00 49.99  ? 110 THR A O   1 
ATOM   870   C CB  . THR A 1 164 ? 116.068 140.783 97.719  1.00 40.48  ? 110 THR A CB  1 
ATOM   871   O OG1 . THR A 1 164 ? 115.988 141.772 96.687  1.00 40.72  ? 110 THR A OG1 1 
ATOM   872   C CG2 . THR A 1 164 ? 115.204 141.217 98.888  1.00 38.78  ? 110 THR A CG2 1 
ATOM   873   N N   . VAL A 1 165 ? 119.254 141.326 96.630  1.00 40.41  ? 111 VAL A N   1 
ATOM   874   C CA  . VAL A 1 165 ? 120.283 141.189 95.613  1.00 42.40  ? 111 VAL A CA  1 
ATOM   875   C C   . VAL A 1 165 ? 121.580 141.704 96.217  1.00 45.54  ? 111 VAL A C   1 
ATOM   876   O O   . VAL A 1 165 ? 121.594 142.282 97.303  1.00 48.75  ? 111 VAL A O   1 
ATOM   877   C CB  . VAL A 1 165 ? 119.946 141.952 94.316  1.00 41.45  ? 111 VAL A CB  1 
ATOM   878   C CG1 . VAL A 1 165 ? 118.609 141.495 93.760  1.00 41.52  ? 111 VAL A CG1 1 
ATOM   879   C CG2 . VAL A 1 165 ? 119.942 143.444 94.574  1.00 41.27  ? 111 VAL A CG2 1 
ATOM   880   N N   . LYS A 1 166 ? 122.682 141.471 95.510  1.00 42.79  ? 112 LYS A N   1 
ATOM   881   C CA  . LYS A 1 166 ? 123.965 141.987 95.965  1.00 43.91  ? 112 LYS A CA  1 
ATOM   882   C C   . LYS A 1 166 ? 123.877 143.497 96.136  1.00 50.92  ? 112 LYS A C   1 
ATOM   883   O O   . LYS A 1 166 ? 123.560 144.220 95.187  1.00 55.87  ? 112 LYS A O   1 
ATOM   884   C CB  . LYS A 1 166 ? 125.070 141.620 94.980  1.00 45.22  ? 112 LYS A CB  1 
ATOM   885   C CG  . LYS A 1 166 ? 125.402 140.140 94.950  1.00 53.71  ? 112 LYS A CG  1 
ATOM   886   C CD  . LYS A 1 166 ? 126.706 139.885 94.221  1.00 60.45  ? 112 LYS A CD  1 
ATOM   887   C CE  . LYS A 1 166 ? 127.862 140.593 94.909  1.00 63.48  ? 112 LYS A CE  1 
ATOM   888   N NZ  . LYS A 1 166 ? 128.011 140.149 96.321  1.00 56.62  ? 112 LYS A NZ  1 
ATOM   889   N N   . ASN A 1 167 ? 124.151 143.971 97.350  1.00 47.61  ? 113 ASN A N   1 
ATOM   890   C CA  . ASN A 1 167 ? 123.998 145.388 97.643  1.00 41.76  ? 113 ASN A CA  1 
ATOM   891   C C   . ASN A 1 167 ? 125.119 146.163 96.970  1.00 47.08  ? 113 ASN A C   1 
ATOM   892   O O   . ASN A 1 167 ? 126.180 146.389 97.558  1.00 47.61  ? 113 ASN A O   1 
ATOM   893   C CB  . ASN A 1 167 ? 123.980 145.637 99.149  1.00 37.93  ? 113 ASN A CB  1 
ATOM   894   C CG  . ASN A 1 167 ? 122.710 145.135 99.802  1.00 43.35  ? 113 ASN A CG  1 
ATOM   895   O OD1 . ASN A 1 167 ? 122.600 145.098 101.026 1.00 45.26  ? 113 ASN A OD1 1 
ATOM   896   N ND2 . ASN A 1 167 ? 121.741 144.742 98.985  1.00 43.33  ? 113 ASN A ND2 1 
ATOM   897   N N   . ARG A 1 168 ? 124.873 146.571 95.730  1.00 47.43  ? 114 ARG A N   1 
ATOM   898   C CA  . ARG A 1 168 ? 125.901 147.121 94.866  1.00 44.89  ? 114 ARG A CA  1 
ATOM   899   C C   . ARG A 1 168 ? 125.221 147.986 93.818  1.00 49.01  ? 114 ARG A C   1 
ATOM   900   O O   . ARG A 1 168 ? 124.151 147.636 93.318  1.00 53.45  ? 114 ARG A O   1 
ATOM   901   C CB  . ARG A 1 168 ? 126.711 145.996 94.216  1.00 46.75  ? 114 ARG A CB  1 
ATOM   902   C CG  . ARG A 1 168 ? 127.664 146.426 93.130  1.00 51.61  ? 114 ARG A CG  1 
ATOM   903   C CD  . ARG A 1 168 ? 128.403 145.219 92.586  1.00 58.77  ? 114 ARG A CD  1 
ATOM   904   N NE  . ARG A 1 168 ? 127.484 144.208 92.079  1.00 65.37  ? 114 ARG A NE  1 
ATOM   905   C CZ  . ARG A 1 168 ? 127.850 143.003 91.666  1.00 69.50  ? 114 ARG A CZ  1 
ATOM   906   N NH1 . ARG A 1 168 ? 129.115 142.616 91.699  1.00 70.04  ? 114 ARG A NH1 1 
ATOM   907   N NH2 . ARG A 1 168 ? 126.924 142.164 91.211  1.00 67.67  ? 114 ARG A NH2 1 
ATOM   908   N N   . MET A 1 169 ? 125.841 149.118 93.503  1.00 48.17  ? 115 MET A N   1 
ATOM   909   C CA  . MET A 1 169 ? 125.246 150.110 92.622  1.00 46.13  ? 115 MET A CA  1 
ATOM   910   C C   . MET A 1 169 ? 126.272 150.580 91.606  1.00 48.28  ? 115 MET A C   1 
ATOM   911   O O   . MET A 1 169 ? 127.381 150.974 91.979  1.00 48.69  ? 115 MET A O   1 
ATOM   912   C CB  . MET A 1 169 ? 124.716 151.302 93.421  1.00 46.70  ? 115 MET A CB  1 
ATOM   913   C CG  . MET A 1 169 ? 124.417 152.523 92.580  1.00 51.83  ? 115 MET A CG  1 
ATOM   914   S SD  . MET A 1 169 ? 123.896 153.919 93.589  1.00 87.24  ? 115 MET A SD  1 
ATOM   915   C CE  . MET A 1 169 ? 125.234 153.989 94.775  1.00 62.43  ? 115 MET A CE  1 
ATOM   916   N N   . ILE A 1 170 ? 125.894 150.544 90.331  1.00 50.13  ? 116 ILE A N   1 
ATOM   917   C CA  . ILE A 1 170 ? 126.709 151.056 89.237  1.00 51.59  ? 116 ILE A CA  1 
ATOM   918   C C   . ILE A 1 170 ? 125.929 152.169 88.554  1.00 56.31  ? 116 ILE A C   1 
ATOM   919   O O   . ILE A 1 170 ? 124.789 151.960 88.114  1.00 65.09  ? 116 ILE A O   1 
ATOM   920   C CB  . ILE A 1 170 ? 127.086 149.952 88.237  1.00 50.84  ? 116 ILE A CB  1 
ATOM   921   C CG1 . ILE A 1 170 ? 128.363 149.244 88.684  1.00 54.55  ? 116 ILE A CG1 1 
ATOM   922   C CG2 . ILE A 1 170 ? 127.279 150.531 86.844  1.00 50.85  ? 116 ILE A CG2 1 
ATOM   923   C CD1 . ILE A 1 170 ? 129.621 150.032 88.391  1.00 49.89  ? 116 ILE A CD1 1 
ATOM   924   N N   . ARG A 1 171 ? 126.537 153.350 88.470  1.00 52.29  ? 117 ARG A N   1 
ATOM   925   C CA  . ARG A 1 171 ? 125.934 154.481 87.783  1.00 54.38  ? 117 ARG A CA  1 
ATOM   926   C C   . ARG A 1 171 ? 126.954 155.079 86.828  1.00 54.84  ? 117 ARG A C   1 
ATOM   927   O O   . ARG A 1 171 ? 128.091 155.357 87.222  1.00 57.55  ? 117 ARG A O   1 
ATOM   928   C CB  . ARG A 1 171 ? 125.441 155.534 88.777  1.00 54.97  ? 117 ARG A CB  1 
ATOM   929   C CG  . ARG A 1 171 ? 124.611 156.633 88.148  1.00 60.15  ? 117 ARG A CG  1 
ATOM   930   C CD  . ARG A 1 171 ? 124.048 157.561 89.205  1.00 63.80  ? 117 ARG A CD  1 
ATOM   931   N NE  . ARG A 1 171 ? 123.063 156.895 90.047  1.00 71.33  ? 117 ARG A NE  1 
ATOM   932   C CZ  . ARG A 1 171 ? 122.449 157.467 91.074  1.00 74.43  ? 117 ARG A CZ  1 
ATOM   933   N NH1 . ARG A 1 171 ? 122.713 158.714 91.429  1.00 69.18  ? 117 ARG A NH1 1 
ATOM   934   N NH2 . ARG A 1 171 ? 121.547 156.771 91.760  1.00 72.57  ? 117 ARG A NH2 1 
ATOM   935   N N   . LEU A 1 172 ? 126.545 155.276 85.579  1.00 52.66  ? 118 LEU A N   1 
ATOM   936   C CA  . LEU A 1 172 ? 127.396 155.832 84.542  1.00 53.52  ? 118 LEU A CA  1 
ATOM   937   C C   . LEU A 1 172 ? 126.924 157.233 84.181  1.00 60.79  ? 118 LEU A C   1 
ATOM   938   O O   . LEU A 1 172 ? 125.726 157.532 84.211  1.00 66.73  ? 118 LEU A O   1 
ATOM   939   C CB  . LEU A 1 172 ? 127.395 154.949 83.292  1.00 55.10  ? 118 LEU A CB  1 
ATOM   940   C CG  . LEU A 1 172 ? 127.692 153.463 83.493  1.00 53.46  ? 118 LEU A CG  1 
ATOM   941   C CD1 . LEU A 1 172 ? 127.714 152.742 82.157  1.00 44.45  ? 118 LEU A CD1 1 
ATOM   942   C CD2 . LEU A 1 172 ? 129.005 153.274 84.227  1.00 57.93  ? 118 LEU A CD2 1 
ATOM   943   N N   . HIS A 1 173 ? 127.881 158.080 83.827  1.00 60.63  ? 119 HIS A N   1 
ATOM   944   C CA  . HIS A 1 173 ? 127.660 159.479 83.511  1.00 63.20  ? 119 HIS A CA  1 
ATOM   945   C C   . HIS A 1 173 ? 128.069 159.754 82.069  1.00 68.17  ? 119 HIS A C   1 
ATOM   946   O O   . HIS A 1 173 ? 128.905 159.037 81.505  1.00 71.75  ? 119 HIS A O   1 
ATOM   947   C CB  . HIS A 1 173 ? 128.457 160.381 84.464  1.00 61.77  ? 119 HIS A CB  1 
ATOM   948   C CG  . HIS A 1 173 ? 128.072 160.232 85.904  1.00 63.91  ? 119 HIS A CG  1 
ATOM   949   N ND1 . HIS A 1 173 ? 128.109 159.023 86.565  1.00 61.69  ? 119 HIS A ND1 1 
ATOM   950   C CD2 . HIS A 1 173 ? 127.647 161.142 86.812  1.00 70.94  ? 119 HIS A CD2 1 
ATOM   951   C CE1 . HIS A 1 173 ? 127.720 159.195 87.816  1.00 62.67  ? 119 HIS A CE1 1 
ATOM   952   N NE2 . HIS A 1 173 ? 127.435 160.472 87.992  1.00 71.70  ? 119 HIS A NE2 1 
ATOM   953   N N   . PRO A 1 174 ? 127.493 160.781 81.436  1.00 68.37  ? 120 PRO A N   1 
ATOM   954   C CA  . PRO A 1 174 ? 127.798 161.031 80.017  1.00 70.08  ? 120 PRO A CA  1 
ATOM   955   C C   . PRO A 1 174 ? 129.271 161.265 79.731  1.00 67.56  ? 120 PRO A C   1 
ATOM   956   O O   . PRO A 1 174 ? 129.751 160.874 78.660  1.00 68.74  ? 120 PRO A O   1 
ATOM   957   C CB  . PRO A 1 174 ? 126.959 162.277 79.698  1.00 70.49  ? 120 PRO A CB  1 
ATOM   958   C CG  . PRO A 1 174 ? 125.847 162.242 80.684  1.00 68.45  ? 120 PRO A CG  1 
ATOM   959   C CD  . PRO A 1 174 ? 126.436 161.675 81.939  1.00 68.19  ? 120 PRO A CD  1 
ATOM   960   N N   . ASP A 1 175 ? 130.004 161.889 80.650  1.00 66.68  ? 121 ASP A N   1 
ATOM   961   C CA  . ASP A 1 175 ? 131.421 162.160 80.443  1.00 65.66  ? 121 ASP A CA  1 
ATOM   962   C C   . ASP A 1 175 ? 132.304 160.943 80.683  1.00 67.40  ? 121 ASP A C   1 
ATOM   963   O O   . ASP A 1 175 ? 133.532 161.069 80.615  1.00 68.71  ? 121 ASP A O   1 
ATOM   964   C CB  . ASP A 1 175 ? 131.874 163.312 81.344  1.00 70.24  ? 121 ASP A CB  1 
ATOM   965   C CG  . ASP A 1 175 ? 131.282 163.232 82.737  1.00 77.28  ? 121 ASP A CG  1 
ATOM   966   O OD1 . ASP A 1 175 ? 130.389 162.389 82.955  1.00 76.85  ? 121 ASP A OD1 1 
ATOM   967   O OD2 . ASP A 1 175 ? 131.706 164.014 83.613  1.00 83.00  ? 121 ASP A OD2 1 
ATOM   968   N N   . GLY A 1 176 ? 131.722 159.779 80.962  1.00 69.10  ? 122 GLY A N   1 
ATOM   969   C CA  . GLY A 1 176 ? 132.482 158.578 81.230  1.00 67.91  ? 122 GLY A CA  1 
ATOM   970   C C   . GLY A 1 176 ? 132.666 158.265 82.698  1.00 64.01  ? 122 GLY A C   1 
ATOM   971   O O   . GLY A 1 176 ? 133.169 157.185 83.026  1.00 63.55  ? 122 GLY A O   1 
ATOM   972   N N   . THR A 1 177 ? 132.277 159.178 83.581  1.00 62.66  ? 123 THR A N   1 
ATOM   973   C CA  . THR A 1 177 ? 132.466 158.981 85.010  1.00 57.71  ? 123 THR A CA  1 
ATOM   974   C C   . THR A 1 177 ? 131.601 157.836 85.522  1.00 57.11  ? 123 THR A C   1 
ATOM   975   O O   . THR A 1 177 ? 130.439 157.688 85.134  1.00 62.45  ? 123 THR A O   1 
ATOM   976   C CB  . THR A 1 177 ? 132.137 160.270 85.758  1.00 59.89  ? 123 THR A CB  1 
ATOM   977   O OG1 . THR A 1 177 ? 132.836 161.362 85.152  1.00 66.82  ? 123 THR A OG1 1 
ATOM   978   C CG2 . THR A 1 177 ? 132.558 160.163 87.203  1.00 56.02  ? 123 THR A CG2 1 
ATOM   979   N N   . VAL A 1 178 ? 132.179 157.023 86.402  1.00 54.32  ? 124 VAL A N   1 
ATOM   980   C CA  . VAL A 1 178 ? 131.522 155.865 86.990  1.00 50.52  ? 124 VAL A CA  1 
ATOM   981   C C   . VAL A 1 178 ? 131.483 156.043 88.500  1.00 52.16  ? 124 VAL A C   1 
ATOM   982   O O   . VAL A 1 178 ? 132.506 156.365 89.124  1.00 58.95  ? 124 VAL A O   1 
ATOM   983   C CB  . VAL A 1 178 ? 132.239 154.554 86.622  1.00 46.51  ? 124 VAL A CB  1 
ATOM   984   C CG1 . VAL A 1 178 ? 131.428 153.359 87.091  1.00 45.29  ? 124 VAL A CG1 1 
ATOM   985   C CG2 . VAL A 1 178 ? 132.485 154.487 85.132  1.00 53.57  ? 124 VAL A CG2 1 
ATOM   986   N N   . LEU A 1 179 ? 130.299 155.835 89.076  1.00 47.87  ? 125 LEU A N   1 
ATOM   987   C CA  . LEU A 1 179 ? 130.090 155.765 90.515  1.00 48.13  ? 125 LEU A CA  1 
ATOM   988   C C   . LEU A 1 179 ? 129.735 154.331 90.884  1.00 48.96  ? 125 LEU A C   1 
ATOM   989   O O   . LEU A 1 179 ? 128.815 153.744 90.299  1.00 55.67  ? 125 LEU A O   1 
ATOM   990   C CB  . LEU A 1 179 ? 128.977 156.716 90.956  1.00 53.24  ? 125 LEU A CB  1 
ATOM   991   C CG  . LEU A 1 179 ? 128.504 156.601 92.407  1.00 52.74  ? 125 LEU A CG  1 
ATOM   992   C CD1 . LEU A 1 179 ? 129.380 157.426 93.335  1.00 51.67  ? 125 LEU A CD1 1 
ATOM   993   C CD2 . LEU A 1 179 ? 127.046 157.013 92.527  1.00 58.18  ? 125 LEU A CD2 1 
ATOM   994   N N   . TYR A 1 180 ? 130.460 153.774 91.851  1.00 43.83  ? 126 TYR A N   1 
ATOM   995   C CA  . TYR A 1 180 ? 130.343 152.370 92.225  1.00 41.53  ? 126 TYR A CA  1 
ATOM   996   C C   . TYR A 1 180 ? 130.216 152.275 93.736  1.00 40.65  ? 126 TYR A C   1 
ATOM   997   O O   . TYR A 1 180 ? 131.147 152.636 94.460  1.00 42.01  ? 126 TYR A O   1 
ATOM   998   C CB  . TYR A 1 180 ? 131.561 151.585 91.729  1.00 40.44  ? 126 TYR A CB  1 
ATOM   999   C CG  . TYR A 1 180 ? 131.560 150.119 92.081  1.00 39.44  ? 126 TYR A CG  1 
ATOM   1000  C CD1 . TYR A 1 180 ? 130.556 149.281 91.630  1.00 42.71  ? 126 TYR A CD1 1 
ATOM   1001  C CD2 . TYR A 1 180 ? 132.580 149.568 92.843  1.00 40.70  ? 126 TYR A CD2 1 
ATOM   1002  C CE1 . TYR A 1 180 ? 130.556 147.942 91.937  1.00 44.96  ? 126 TYR A CE1 1 
ATOM   1003  C CE2 . TYR A 1 180 ? 132.587 148.226 93.156  1.00 43.87  ? 126 TYR A CE2 1 
ATOM   1004  C CZ  . TYR A 1 180 ? 131.571 147.418 92.700  1.00 44.60  ? 126 TYR A CZ  1 
ATOM   1005  O OH  . TYR A 1 180 ? 131.567 146.078 93.004  1.00 44.80  ? 126 TYR A OH  1 
ATOM   1006  N N   . GLY A 1 181 ? 129.078 151.781 94.212  1.00 38.97  ? 127 GLY A N   1 
ATOM   1007  C CA  . GLY A 1 181 ? 128.794 151.739 95.634  1.00 39.92  ? 127 GLY A CA  1 
ATOM   1008  C C   . GLY A 1 181 ? 128.549 150.327 96.126  1.00 40.10  ? 127 GLY A C   1 
ATOM   1009  O O   . GLY A 1 181 ? 127.973 149.500 95.421  1.00 48.36  ? 127 GLY A O   1 
ATOM   1010  N N   . LEU A 1 182 ? 128.983 150.063 97.358  1.00 35.30  ? 128 LEU A N   1 
ATOM   1011  C CA  . LEU A 1 182 ? 128.828 148.758 97.985  1.00 36.08  ? 128 LEU A CA  1 
ATOM   1012  C C   . LEU A 1 182 ? 128.435 148.927 99.443  1.00 39.28  ? 128 LEU A C   1 
ATOM   1013  O O   . LEU A 1 182 ? 128.980 149.784 100.141 1.00 41.28  ? 128 LEU A O   1 
ATOM   1014  C CB  . LEU A 1 182 ? 130.121 147.941 97.912  1.00 31.32  ? 128 LEU A CB  1 
ATOM   1015  C CG  . LEU A 1 182 ? 130.656 147.537 96.544  1.00 34.11  ? 128 LEU A CG  1 
ATOM   1016  C CD1 . LEU A 1 182 ? 132.133 147.236 96.656  1.00 32.57  ? 128 LEU A CD1 1 
ATOM   1017  C CD2 . LEU A 1 182 ? 129.909 146.324 96.032  1.00 40.76  ? 128 LEU A CD2 1 
ATOM   1018  N N   . ARG A 1 183 ? 127.501 148.103 99.909  1.00 33.80  ? 129 ARG A N   1 
ATOM   1019  C CA  . ARG A 1 183 ? 127.164 148.041 101.326 1.00 32.58  ? 129 ARG A CA  1 
ATOM   1020  C C   . ARG A 1 183 ? 127.991 146.923 101.945 1.00 34.05  ? 129 ARG A C   1 
ATOM   1021  O O   . ARG A 1 183 ? 127.748 145.742 101.680 1.00 42.90  ? 129 ARG A O   1 
ATOM   1022  C CB  . ARG A 1 183 ? 125.671 147.813 101.540 1.00 37.03  ? 129 ARG A CB  1 
ATOM   1023  C CG  . ARG A 1 183 ? 125.245 147.990 102.984 1.00 36.93  ? 129 ARG A CG  1 
ATOM   1024  C CD  . ARG A 1 183 ? 123.776 148.338 103.091 1.00 36.51  ? 129 ARG A CD  1 
ATOM   1025  N NE  . ARG A 1 183 ? 122.922 147.161 103.008 1.00 40.84  ? 129 ARG A NE  1 
ATOM   1026  C CZ  . ARG A 1 183 ? 122.456 146.504 104.060 1.00 42.36  ? 129 ARG A CZ  1 
ATOM   1027  N NH1 . ARG A 1 183 ? 122.753 146.878 105.294 1.00 43.09  ? 129 ARG A NH1 1 
ATOM   1028  N NH2 . ARG A 1 183 ? 121.670 145.449 103.870 1.00 41.69  ? 129 ARG A NH2 1 
ATOM   1029  N N   . ILE A 1 184 ? 128.962 147.298 102.772 1.00 32.53  ? 130 ILE A N   1 
ATOM   1030  C CA  . ILE A 1 184 ? 129.987 146.385 103.263 1.00 33.61  ? 130 ILE A CA  1 
ATOM   1031  C C   . ILE A 1 184 ? 129.946 146.366 104.783 1.00 35.13  ? 130 ILE A C   1 
ATOM   1032  O O   . ILE A 1 184 ? 129.929 147.426 105.421 1.00 44.37  ? 130 ILE A O   1 
ATOM   1033  C CB  . ILE A 1 184 ? 131.386 146.794 102.767 1.00 32.38  ? 130 ILE A CB  1 
ATOM   1034  C CG1 . ILE A 1 184 ? 131.443 146.772 101.241 1.00 30.83  ? 130 ILE A CG1 1 
ATOM   1035  C CG2 . ILE A 1 184 ? 132.451 145.892 103.363 1.00 37.24  ? 130 ILE A CG2 1 
ATOM   1036  C CD1 . ILE A 1 184 ? 132.771 147.223 100.684 1.00 32.55  ? 130 ILE A CD1 1 
ATOM   1037  N N   . THR A 1 185 ? 129.933 145.166 105.356 1.00 33.18  ? 131 THR A N   1 
ATOM   1038  C CA  . THR A 1 185 ? 130.086 144.966 106.792 1.00 38.23  ? 131 THR A CA  1 
ATOM   1039  C C   . THR A 1 185 ? 131.443 144.318 107.028 1.00 40.91  ? 131 THR A C   1 
ATOM   1040  O O   . THR A 1 185 ? 131.667 143.171 106.629 1.00 46.90  ? 131 THR A O   1 
ATOM   1041  C CB  . THR A 1 185 ? 128.959 144.105 107.360 1.00 43.13  ? 131 THR A CB  1 
ATOM   1042  O OG1 . THR A 1 185 ? 127.711 144.788 107.203 1.00 46.91  ? 131 THR A OG1 1 
ATOM   1043  C CG2 . THR A 1 185 ? 129.195 143.831 108.836 1.00 40.76  ? 131 THR A CG2 1 
ATOM   1044  N N   . THR A 1 186 ? 132.339 145.051 107.676 1.00 40.95  ? 132 THR A N   1 
ATOM   1045  C CA  . THR A 1 186 ? 133.688 144.594 107.958 1.00 48.89  ? 132 THR A CA  1 
ATOM   1046  C C   . THR A 1 186 ? 133.880 144.408 109.457 1.00 52.28  ? 132 THR A C   1 
ATOM   1047  O O   . THR A 1 186 ? 133.098 144.900 110.273 1.00 55.31  ? 132 THR A O   1 
ATOM   1048  C CB  . THR A 1 186 ? 134.730 145.582 107.420 1.00 48.64  ? 132 THR A CB  1 
ATOM   1049  O OG1 . THR A 1 186 ? 136.040 145.166 107.821 1.00 53.21  ? 132 THR A OG1 1 
ATOM   1050  C CG2 . THR A 1 186 ? 134.465 146.977 107.955 1.00 45.65  ? 132 THR A CG2 1 
ATOM   1051  N N   . THR A 1 187 ? 134.935 143.675 109.809 1.00 49.86  ? 133 THR A N   1 
ATOM   1052  C CA  . THR A 1 187 ? 135.355 143.479 111.196 1.00 47.85  ? 133 THR A CA  1 
ATOM   1053  C C   . THR A 1 187 ? 136.838 143.829 111.227 1.00 51.66  ? 133 THR A C   1 
ATOM   1054  O O   . THR A 1 187 ? 137.688 142.984 110.942 1.00 56.71  ? 133 THR A O   1 
ATOM   1055  C CB  . THR A 1 187 ? 135.092 142.052 111.668 1.00 49.28  ? 133 THR A CB  1 
ATOM   1056  O OG1 . THR A 1 187 ? 133.704 141.741 111.503 1.00 50.68  ? 133 THR A OG1 1 
ATOM   1057  C CG2 . THR A 1 187 ? 135.463 141.897 113.132 1.00 51.90  ? 133 THR A CG2 1 
ATOM   1058  N N   . ALA A 1 188 ? 137.149 145.074 111.563 1.00 54.40  ? 134 ALA A N   1 
ATOM   1059  C CA  . ALA A 1 188 ? 138.512 145.574 111.467 1.00 56.68  ? 134 ALA A CA  1 
ATOM   1060  C C   . ALA A 1 188 ? 139.227 145.426 112.800 1.00 53.97  ? 134 ALA A C   1 
ATOM   1061  O O   . ALA A 1 188 ? 138.654 145.695 113.859 1.00 60.85  ? 134 ALA A O   1 
ATOM   1062  C CB  . ALA A 1 188 ? 138.526 147.038 111.024 1.00 57.98  ? 134 ALA A CB  1 
ATOM   1063  N N   . ALA A 1 189 ? 140.490 145.014 112.738 1.00 46.80  ? 135 ALA A N   1 
ATOM   1064  C CA  . ALA A 1 189 ? 141.270 144.795 113.947 1.00 48.62  ? 135 ALA A CA  1 
ATOM   1065  C C   . ALA A 1 189 ? 141.710 146.125 114.542 1.00 58.20  ? 135 ALA A C   1 
ATOM   1066  O O   . ALA A 1 189 ? 142.311 146.957 113.857 1.00 60.62  ? 135 ALA A O   1 
ATOM   1067  C CB  . ALA A 1 189 ? 142.487 143.923 113.644 1.00 39.32  ? 135 ALA A CB  1 
ATOM   1068  N N   . CYS A 1 190 ? 141.409 146.322 115.823 1.00 62.90  ? 136 CYS A N   1 
ATOM   1069  C CA  . CYS A 1 190 ? 141.766 147.541 116.546 1.00 64.84  ? 136 CYS A CA  1 
ATOM   1070  C C   . CYS A 1 190 ? 142.539 147.132 117.794 1.00 71.48  ? 136 CYS A C   1 
ATOM   1071  O O   . CYS A 1 190 ? 141.946 146.667 118.771 1.00 73.56  ? 136 CYS A O   1 
ATOM   1072  C CB  . CYS A 1 190 ? 140.525 148.355 116.897 1.00 66.41  ? 136 CYS A CB  1 
ATOM   1073  S SG  . CYS A 1 190 ? 140.859 149.885 117.799 1.00 92.35  ? 136 CYS A SG  1 
ATOM   1074  N N   . MET A 1 191 ? 143.859 147.299 117.761 1.00 71.72  ? 137 MET A N   1 
ATOM   1075  C CA  . MET A 1 191 ? 144.688 146.977 118.916 1.00 74.17  ? 137 MET A CA  1 
ATOM   1076  C C   . MET A 1 191 ? 144.479 148.026 120.000 1.00 77.52  ? 137 MET A C   1 
ATOM   1077  O O   . MET A 1 191 ? 144.683 149.222 119.765 1.00 81.90  ? 137 MET A O   1 
ATOM   1078  C CB  . MET A 1 191 ? 146.156 146.900 118.512 1.00 73.71  ? 137 MET A CB  1 
ATOM   1079  C CG  . MET A 1 191 ? 146.528 145.617 117.795 1.00 83.29  ? 137 MET A CG  1 
ATOM   1080  S SD  . MET A 1 191 ? 146.346 144.175 118.862 1.00 107.12 ? 137 MET A SD  1 
ATOM   1081  C CE  . MET A 1 191 ? 146.805 142.858 117.742 1.00 105.67 ? 137 MET A CE  1 
ATOM   1082  N N   . MET A 1 192 ? 144.073 147.581 121.184 1.00 71.60  ? 138 MET A N   1 
ATOM   1083  C CA  . MET A 1 192 ? 143.662 148.470 122.260 1.00 67.40  ? 138 MET A CA  1 
ATOM   1084  C C   . MET A 1 192 ? 144.655 148.403 123.410 1.00 68.46  ? 138 MET A C   1 
ATOM   1085  O O   . MET A 1 192 ? 145.085 147.314 123.804 1.00 73.26  ? 138 MET A O   1 
ATOM   1086  C CB  . MET A 1 192 ? 142.264 148.106 122.759 1.00 69.86  ? 138 MET A CB  1 
ATOM   1087  C CG  . MET A 1 192 ? 141.224 148.031 121.664 1.00 74.12  ? 138 MET A CG  1 
ATOM   1088  S SD  . MET A 1 192 ? 139.608 147.549 122.287 1.00 84.95  ? 138 MET A SD  1 
ATOM   1089  C CE  . MET A 1 192 ? 138.738 147.276 120.748 1.00 69.68  ? 138 MET A CE  1 
ATOM   1090  N N   . ASP A 1 193 ? 145.011 149.568 123.942 1.00 68.58  ? 139 ASP A N   1 
ATOM   1091  C CA  . ASP A 1 193 ? 145.798 149.666 125.165 1.00 70.30  ? 139 ASP A CA  1 
ATOM   1092  C C   . ASP A 1 193 ? 144.829 149.755 126.337 1.00 67.40  ? 139 ASP A C   1 
ATOM   1093  O O   . ASP A 1 193 ? 144.143 150.768 126.508 1.00 69.13  ? 139 ASP A O   1 
ATOM   1094  C CB  . ASP A 1 193 ? 146.722 150.879 125.117 1.00 73.47  ? 139 ASP A CB  1 
ATOM   1095  C CG  . ASP A 1 193 ? 147.552 151.027 126.373 1.00 72.25  ? 139 ASP A CG  1 
ATOM   1096  O OD1 . ASP A 1 193 ? 147.739 150.020 127.086 1.00 73.43  ? 139 ASP A OD1 1 
ATOM   1097  O OD2 . ASP A 1 193 ? 148.013 152.154 126.654 1.00 70.45  ? 139 ASP A OD2 1 
ATOM   1098  N N   . LEU A 1 194 ? 144.769 148.697 127.144 1.00 59.85  ? 140 LEU A N   1 
ATOM   1099  C CA  . LEU A 1 194 ? 143.814 148.607 128.239 1.00 58.78  ? 140 LEU A CA  1 
ATOM   1100  C C   . LEU A 1 194 ? 144.430 148.955 129.588 1.00 58.64  ? 140 LEU A C   1 
ATOM   1101  O O   . LEU A 1 194 ? 143.874 148.586 130.627 1.00 58.33  ? 140 LEU A O   1 
ATOM   1102  C CB  . LEU A 1 194 ? 143.200 147.207 128.288 1.00 53.31  ? 140 LEU A CB  1 
ATOM   1103  C CG  . LEU A 1 194 ? 142.479 146.729 127.029 1.00 51.87  ? 140 LEU A CG  1 
ATOM   1104  C CD1 . LEU A 1 194 ? 141.876 145.354 127.255 1.00 48.09  ? 140 LEU A CD1 1 
ATOM   1105  C CD2 . LEU A 1 194 ? 141.409 147.722 126.616 1.00 52.84  ? 140 LEU A CD2 1 
ATOM   1106  N N   . ARG A 1 195 ? 145.561 149.662 129.596 1.00 59.26  ? 141 ARG A N   1 
ATOM   1107  C CA  . ARG A 1 195 ? 146.205 150.010 130.857 1.00 58.51  ? 141 ARG A CA  1 
ATOM   1108  C C   . ARG A 1 195 ? 145.365 150.960 131.700 1.00 55.99  ? 141 ARG A C   1 
ATOM   1109  O O   . ARG A 1 195 ? 145.598 151.068 132.908 1.00 60.91  ? 141 ARG A O   1 
ATOM   1110  C CB  . ARG A 1 195 ? 147.581 150.618 130.593 1.00 61.93  ? 141 ARG A CB  1 
ATOM   1111  C CG  . ARG A 1 195 ? 148.629 149.597 130.192 1.00 65.22  ? 141 ARG A CG  1 
ATOM   1112  C CD  . ARG A 1 195 ? 149.922 150.260 129.767 1.00 67.26  ? 141 ARG A CD  1 
ATOM   1113  N NE  . ARG A 1 195 ? 150.965 149.279 129.495 1.00 80.32  ? 141 ARG A NE  1 
ATOM   1114  C CZ  . ARG A 1 195 ? 151.095 148.619 128.352 1.00 85.05  ? 141 ARG A CZ  1 
ATOM   1115  N NH1 . ARG A 1 195 ? 150.257 148.809 127.345 1.00 83.80  ? 141 ARG A NH1 1 
ATOM   1116  N NH2 . ARG A 1 195 ? 152.089 147.747 128.215 1.00 82.95  ? 141 ARG A NH2 1 
ATOM   1117  N N   . ARG A 1 196 ? 144.399 151.653 131.097 1.00 55.86  ? 142 ARG A N   1 
ATOM   1118  C CA  . ARG A 1 196 ? 143.521 152.561 131.822 1.00 54.07  ? 142 ARG A CA  1 
ATOM   1119  C C   . ARG A 1 196 ? 142.072 152.090 131.804 1.00 52.79  ? 142 ARG A C   1 
ATOM   1120  O O   . ARG A 1 196 ? 141.166 152.871 132.106 1.00 52.51  ? 142 ARG A O   1 
ATOM   1121  C CB  . ARG A 1 196 ? 143.634 153.972 131.248 1.00 53.87  ? 142 ARG A CB  1 
ATOM   1122  C CG  . ARG A 1 196 ? 145.065 154.423 131.023 1.00 55.66  ? 142 ARG A CG  1 
ATOM   1123  C CD  . ARG A 1 196 ? 145.122 155.813 130.418 1.00 63.08  ? 142 ARG A CD  1 
ATOM   1124  N NE  . ARG A 1 196 ? 144.949 156.856 131.421 1.00 67.55  ? 142 ARG A NE  1 
ATOM   1125  C CZ  . ARG A 1 196 ? 145.946 157.425 132.085 1.00 70.07  ? 142 ARG A CZ  1 
ATOM   1126  N NH1 . ARG A 1 196 ? 147.204 157.072 131.878 1.00 69.64  ? 142 ARG A NH1 1 
ATOM   1127  N NH2 . ARG A 1 196 ? 145.674 158.372 132.979 1.00 66.38  ? 142 ARG A NH2 1 
ATOM   1128  N N   . TYR A 1 197 ? 141.842 150.830 131.454 1.00 50.46  ? 143 TYR A N   1 
ATOM   1129  C CA  . TYR A 1 197 ? 140.495 150.283 131.430 1.00 47.58  ? 143 TYR A CA  1 
ATOM   1130  C C   . TYR A 1 197 ? 139.886 150.342 132.829 1.00 53.63  ? 143 TYR A C   1 
ATOM   1131  O O   . TYR A 1 197 ? 140.562 150.022 133.812 1.00 61.77  ? 143 TYR A O   1 
ATOM   1132  C CB  . TYR A 1 197 ? 140.537 148.841 130.924 1.00 45.62  ? 143 TYR A CB  1 
ATOM   1133  C CG  . TYR A 1 197 ? 139.196 148.171 130.743 1.00 46.36  ? 143 TYR A CG  1 
ATOM   1134  C CD1 . TYR A 1 197 ? 138.601 147.472 131.783 1.00 46.96  ? 143 TYR A CD1 1 
ATOM   1135  C CD2 . TYR A 1 197 ? 138.539 148.212 129.524 1.00 53.24  ? 143 TYR A CD2 1 
ATOM   1136  C CE1 . TYR A 1 197 ? 137.383 146.849 131.617 1.00 49.07  ? 143 TYR A CE1 1 
ATOM   1137  C CE2 . TYR A 1 197 ? 137.320 147.591 129.350 1.00 54.83  ? 143 TYR A CE2 1 
ATOM   1138  C CZ  . TYR A 1 197 ? 136.747 146.912 130.399 1.00 50.57  ? 143 TYR A CZ  1 
ATOM   1139  O OH  . TYR A 1 197 ? 135.531 146.292 130.229 1.00 53.81  ? 143 TYR A OH  1 
ATOM   1140  N N   . PRO A 1 198 ? 138.611 150.737 132.961 1.00 51.09  ? 144 PRO A N   1 
ATOM   1141  C CA  . PRO A 1 198 ? 137.655 151.106 131.911 1.00 52.51  ? 144 PRO A CA  1 
ATOM   1142  C C   . PRO A 1 198 ? 137.688 152.583 131.528 1.00 59.20  ? 144 PRO A C   1 
ATOM   1143  O O   . PRO A 1 198 ? 136.871 153.027 130.730 1.00 61.37  ? 144 PRO A O   1 
ATOM   1144  C CB  . PRO A 1 198 ? 136.317 150.730 132.548 1.00 49.30  ? 144 PRO A CB  1 
ATOM   1145  C CG  . PRO A 1 198 ? 136.523 151.070 133.993 1.00 49.02  ? 144 PRO A CG  1 
ATOM   1146  C CD  . PRO A 1 198 ? 137.963 150.708 134.285 1.00 52.04  ? 144 PRO A CD  1 
ATOM   1147  N N   . LEU A 1 199 ? 138.609 153.377 132.075 1.00 56.04  ? 145 LEU A N   1 
ATOM   1148  C CA  . LEU A 1 199 ? 138.689 154.800 131.769 1.00 53.21  ? 145 LEU A CA  1 
ATOM   1149  C C   . LEU A 1 199 ? 139.586 155.089 130.571 1.00 57.82  ? 145 LEU A C   1 
ATOM   1150  O O   . LEU A 1 199 ? 140.126 156.197 130.457 1.00 62.50  ? 145 LEU A O   1 
ATOM   1151  C CB  . LEU A 1 199 ? 139.173 155.577 132.994 1.00 49.76  ? 145 LEU A CB  1 
ATOM   1152  C CG  . LEU A 1 199 ? 138.506 155.261 134.334 1.00 48.38  ? 145 LEU A CG  1 
ATOM   1153  C CD1 . LEU A 1 199 ? 139.331 154.262 135.129 1.00 51.14  ? 145 LEU A CD1 1 
ATOM   1154  C CD2 . LEU A 1 199 ? 138.287 156.529 135.136 1.00 50.44  ? 145 LEU A CD2 1 
ATOM   1155  N N   . ASP A 1 200 ? 139.757 154.123 129.677 1.00 56.63  ? 146 ASP A N   1 
ATOM   1156  C CA  . ASP A 1 200 ? 140.679 154.245 128.560 1.00 55.82  ? 146 ASP A CA  1 
ATOM   1157  C C   . ASP A 1 200 ? 140.031 154.982 127.392 1.00 60.57  ? 146 ASP A C   1 
ATOM   1158  O O   . ASP A 1 200 ? 138.814 155.163 127.327 1.00 63.88  ? 146 ASP A O   1 
ATOM   1159  C CB  . ASP A 1 200 ? 141.153 152.866 128.110 1.00 56.97  ? 146 ASP A CB  1 
ATOM   1160  C CG  . ASP A 1 200 ? 140.008 151.967 127.694 1.00 58.45  ? 146 ASP A CG  1 
ATOM   1161  O OD1 . ASP A 1 200 ? 138.871 152.196 128.158 1.00 58.74  ? 146 ASP A OD1 1 
ATOM   1162  O OD2 . ASP A 1 200 ? 140.243 151.031 126.904 1.00 59.22  ? 146 ASP A OD2 1 
ATOM   1163  N N   . GLU A 1 201 ? 140.875 155.409 126.456 1.00 67.36  ? 147 GLU A N   1 
ATOM   1164  C CA  . GLU A 1 201 ? 140.438 156.081 125.239 1.00 67.67  ? 147 GLU A CA  1 
ATOM   1165  C C   . GLU A 1 201 ? 141.142 155.426 124.063 1.00 68.60  ? 147 GLU A C   1 
ATOM   1166  O O   . GLU A 1 201 ? 142.371 155.496 123.955 1.00 71.12  ? 147 GLU A O   1 
ATOM   1167  C CB  . GLU A 1 201 ? 140.747 157.578 125.298 1.00 68.75  ? 147 GLU A CB  1 
ATOM   1168  C CG  . GLU A 1 201 ? 140.135 158.387 124.176 1.00 73.28  ? 147 GLU A CG  1 
ATOM   1169  C CD  . GLU A 1 201 ? 140.392 159.870 124.334 1.00 83.72  ? 147 GLU A CD  1 
ATOM   1170  O OE1 . GLU A 1 201 ? 141.190 160.243 125.219 1.00 78.20  ? 147 GLU A OE1 1 
ATOM   1171  O OE2 . GLU A 1 201 ? 139.792 160.663 123.578 1.00 90.06  ? 147 GLU A OE2 1 
ATOM   1172  N N   . GLN A 1 202 ? 140.370 154.796 123.187 1.00 66.77  ? 148 GLN A N   1 
ATOM   1173  C CA  . GLN A 1 202 ? 140.917 154.000 122.100 1.00 66.91  ? 148 GLN A CA  1 
ATOM   1174  C C   . GLN A 1 202 ? 140.883 154.772 120.787 1.00 69.61  ? 148 GLN A C   1 
ATOM   1175  O O   . GLN A 1 202 ? 140.158 155.754 120.633 1.00 70.90  ? 148 GLN A O   1 
ATOM   1176  C CB  . GLN A 1 202 ? 140.147 152.685 121.958 1.00 64.42  ? 148 GLN A CB  1 
ATOM   1177  C CG  . GLN A 1 202 ? 140.118 151.852 123.228 1.00 65.95  ? 148 GLN A CG  1 
ATOM   1178  C CD  . GLN A 1 202 ? 141.504 151.469 123.710 1.00 72.67  ? 148 GLN A CD  1 
ATOM   1179  O OE1 . GLN A 1 202 ? 142.448 151.384 122.924 1.00 77.04  ? 148 GLN A OE1 1 
ATOM   1180  N NE2 . GLN A 1 202 ? 141.635 151.240 125.011 1.00 69.78  ? 148 GLN A NE2 1 
ATOM   1181  N N   . ASN A 1 203 ? 141.683 154.302 119.832 1.00 69.48  ? 149 ASN A N   1 
ATOM   1182  C CA  . ASN A 1 203 ? 141.800 154.926 118.514 1.00 66.78  ? 149 ASN A CA  1 
ATOM   1183  C C   . ASN A 1 203 ? 141.754 153.804 117.481 1.00 69.22  ? 149 ASN A C   1 
ATOM   1184  O O   . ASN A 1 203 ? 142.765 153.138 117.237 1.00 77.82  ? 149 ASN A O   1 
ATOM   1185  C CB  . ASN A 1 203 ? 143.083 155.746 118.412 1.00 68.15  ? 149 ASN A CB  1 
ATOM   1186  C CG  . ASN A 1 203 ? 143.346 156.272 117.011 1.00 72.03  ? 149 ASN A CG  1 
ATOM   1187  O OD1 . ASN A 1 203 ? 142.465 156.276 116.152 1.00 71.18  ? 149 ASN A OD1 1 
ATOM   1188  N ND2 . ASN A 1 203 ? 144.572 156.731 116.781 1.00 77.00  ? 149 ASN A ND2 1 
ATOM   1189  N N   . CYS A 1 204 ? 140.586 153.598 116.878 1.00 63.91  ? 150 CYS A N   1 
ATOM   1190  C CA  . CYS A 1 204 ? 140.377 152.511 115.931 1.00 63.86  ? 150 CYS A CA  1 
ATOM   1191  C C   . CYS A 1 204 ? 140.359 153.056 114.510 1.00 64.55  ? 150 CYS A C   1 
ATOM   1192  O O   . CYS A 1 204 ? 139.647 154.022 114.219 1.00 68.80  ? 150 CYS A O   1 
ATOM   1193  C CB  . CYS A 1 204 ? 139.075 151.766 116.231 1.00 67.94  ? 150 CYS A CB  1 
ATOM   1194  S SG  . CYS A 1 204 ? 139.084 150.875 117.804 1.00 100.34 ? 150 CYS A SG  1 
ATOM   1195  N N   . THR A 1 205 ? 141.132 152.431 113.627 1.00 65.49  ? 151 THR A N   1 
ATOM   1196  C CA  . THR A 1 205 ? 141.322 152.927 112.273 1.00 59.82  ? 151 THR A CA  1 
ATOM   1197  C C   . THR A 1 205 ? 140.872 151.900 111.245 1.00 55.08  ? 151 THR A C   1 
ATOM   1198  O O   . THR A 1 205 ? 140.922 150.690 111.481 1.00 60.15  ? 151 THR A O   1 
ATOM   1199  C CB  . THR A 1 205 ? 142.790 153.277 112.009 1.00 63.26  ? 151 THR A CB  1 
ATOM   1200  O OG1 . THR A 1 205 ? 143.576 152.080 112.032 1.00 65.66  ? 151 THR A OG1 1 
ATOM   1201  C CG2 . THR A 1 205 ? 143.309 154.235 113.065 1.00 65.97  ? 151 THR A CG2 1 
ATOM   1202  N N   . LEU A 1 206 ? 140.438 152.405 110.095 1.00 50.32  ? 152 LEU A N   1 
ATOM   1203  C CA  . LEU A 1 206 ? 140.172 151.606 108.910 1.00 50.04  ? 152 LEU A CA  1 
ATOM   1204  C C   . LEU A 1 206 ? 141.111 152.074 107.809 1.00 46.52  ? 152 LEU A C   1 
ATOM   1205  O O   . LEU A 1 206 ? 141.152 153.269 107.492 1.00 52.29  ? 152 LEU A O   1 
ATOM   1206  C CB  . LEU A 1 206 ? 138.713 151.737 108.466 1.00 45.21  ? 152 LEU A CB  1 
ATOM   1207  C CG  . LEU A 1 206 ? 138.284 150.911 107.254 1.00 39.00  ? 152 LEU A CG  1 
ATOM   1208  C CD1 . LEU A 1 206 ? 138.277 149.430 107.590 1.00 41.58  ? 152 LEU A CD1 1 
ATOM   1209  C CD2 . LEU A 1 206 ? 136.920 151.356 106.761 1.00 39.98  ? 152 LEU A CD2 1 
ATOM   1210  N N   . GLU A 1 207 ? 141.862 151.139 107.236 1.00 39.31  ? 153 GLU A N   1 
ATOM   1211  C CA  . GLU A 1 207 ? 142.882 151.439 106.242 1.00 40.31  ? 153 GLU A CA  1 
ATOM   1212  C C   . GLU A 1 207 ? 142.438 150.896 104.892 1.00 44.32  ? 153 GLU A C   1 
ATOM   1213  O O   . GLU A 1 207 ? 142.087 149.719 104.779 1.00 45.59  ? 153 GLU A O   1 
ATOM   1214  C CB  . GLU A 1 207 ? 144.227 150.829 106.637 1.00 45.12  ? 153 GLU A CB  1 
ATOM   1215  C CG  . GLU A 1 207 ? 144.649 151.112 108.065 1.00 51.76  ? 153 GLU A CG  1 
ATOM   1216  C CD  . GLU A 1 207 ? 145.095 152.543 108.268 1.00 63.50  ? 153 GLU A CD  1 
ATOM   1217  O OE1 . GLU A 1 207 ? 145.482 153.190 107.273 1.00 63.64  ? 153 GLU A OE1 1 
ATOM   1218  O OE2 . GLU A 1 207 ? 145.059 153.021 109.421 1.00 66.82  ? 153 GLU A OE2 1 
ATOM   1219  N N   . ILE A 1 208 ? 142.466 151.750 103.874 1.00 43.02  ? 154 ILE A N   1 
ATOM   1220  C CA  . ILE A 1 208 ? 141.948 151.445 102.549 1.00 39.27  ? 154 ILE A CA  1 
ATOM   1221  C C   . ILE A 1 208 ? 143.095 151.572 101.562 1.00 40.21  ? 154 ILE A C   1 
ATOM   1222  O O   . ILE A 1 208 ? 143.782 152.600 101.537 1.00 47.58  ? 154 ILE A O   1 
ATOM   1223  C CB  . ILE A 1 208 ? 140.793 152.390 102.176 1.00 40.07  ? 154 ILE A CB  1 
ATOM   1224  C CG1 . ILE A 1 208 ? 139.784 152.457 103.322 1.00 39.47  ? 154 ILE A CG1 1 
ATOM   1225  C CG2 . ILE A 1 208 ? 140.125 151.935 100.906 1.00 41.00  ? 154 ILE A CG2 1 
ATOM   1226  C CD1 . ILE A 1 208 ? 138.710 153.496 103.133 1.00 41.85  ? 154 ILE A CD1 1 
ATOM   1227  N N   . GLU A 1 209 ? 143.298 150.539 100.748 1.00 41.44  ? 155 GLU A N   1 
ATOM   1228  C CA  . GLU A 1 209 ? 144.474 150.497 99.896  1.00 44.27  ? 155 GLU A CA  1 
ATOM   1229  C C   . GLU A 1 209 ? 144.144 149.776 98.598  1.00 48.44  ? 155 GLU A C   1 
ATOM   1230  O O   . GLU A 1 209 ? 143.181 149.012 98.513  1.00 53.12  ? 155 GLU A O   1 
ATOM   1231  C CB  . GLU A 1 209 ? 145.640 149.816 100.621 1.00 48.71  ? 155 GLU A CB  1 
ATOM   1232  C CG  . GLU A 1 209 ? 146.984 149.948 99.937  1.00 54.35  ? 155 GLU A CG  1 
ATOM   1233  C CD  . GLU A 1 209 ? 148.136 149.744 100.890 1.00 66.61  ? 155 GLU A CD  1 
ATOM   1234  O OE1 . GLU A 1 209 ? 147.898 149.748 102.116 1.00 70.46  ? 155 GLU A OE1 1 
ATOM   1235  O OE2 . GLU A 1 209 ? 149.278 149.583 100.416 1.00 70.64  ? 155 GLU A OE2 1 
ATOM   1236  N N   . SER A 1 210 ? 144.948 150.046 97.574  1.00 45.80  ? 156 SER A N   1 
ATOM   1237  C CA  . SER A 1 210 ? 144.867 149.320 96.316  1.00 46.20  ? 156 SER A CA  1 
ATOM   1238  C C   . SER A 1 210 ? 145.815 148.132 96.373  1.00 51.57  ? 156 SER A C   1 
ATOM   1239  O O   . SER A 1 210 ? 146.998 148.290 96.688  1.00 58.37  ? 156 SER A O   1 
ATOM   1240  C CB  . SER A 1 210 ? 145.215 150.225 95.137  1.00 48.91  ? 156 SER A CB  1 
ATOM   1241  O OG  . SER A 1 210 ? 145.146 149.506 93.919  1.00 51.30  ? 156 SER A OG  1 
ATOM   1242  N N   . TYR A 1 211 ? 145.293 146.945 96.067  1.00 49.00  ? 157 TYR A N   1 
ATOM   1243  C CA  . TYR A 1 211 ? 146.064 145.731 96.306  1.00 48.49  ? 157 TYR A CA  1 
ATOM   1244  C C   . TYR A 1 211 ? 147.180 145.540 95.286  1.00 49.96  ? 157 TYR A C   1 
ATOM   1245  O O   . TYR A 1 211 ? 148.292 145.146 95.652  1.00 53.51  ? 157 TYR A O   1 
ATOM   1246  C CB  . TYR A 1 211 ? 145.145 144.512 96.313  1.00 44.73  ? 157 TYR A CB  1 
ATOM   1247  C CG  . TYR A 1 211 ? 145.837 143.283 96.838  1.00 47.74  ? 157 TYR A CG  1 
ATOM   1248  C CD1 . TYR A 1 211 ? 145.864 143.009 98.195  1.00 48.42  ? 157 TYR A CD1 1 
ATOM   1249  C CD2 . TYR A 1 211 ? 146.487 142.411 95.982  1.00 46.75  ? 157 TYR A CD2 1 
ATOM   1250  C CE1 . TYR A 1 211 ? 146.505 141.897 98.681  1.00 45.50  ? 157 TYR A CE1 1 
ATOM   1251  C CE2 . TYR A 1 211 ? 147.131 141.297 96.461  1.00 46.85  ? 157 TYR A CE2 1 
ATOM   1252  C CZ  . TYR A 1 211 ? 147.137 141.046 97.810  1.00 47.21  ? 157 TYR A CZ  1 
ATOM   1253  O OH  . TYR A 1 211 ? 147.781 139.935 98.287  1.00 64.86  ? 157 TYR A OH  1 
ATOM   1254  N N   . GLY A 1 212 ? 146.912 145.807 94.011  1.00 49.48  ? 158 GLY A N   1 
ATOM   1255  C CA  . GLY A 1 212 ? 147.883 145.488 92.984  1.00 49.17  ? 158 GLY A CA  1 
ATOM   1256  C C   . GLY A 1 212 ? 148.445 146.677 92.234  1.00 52.30  ? 158 GLY A C   1 
ATOM   1257  O O   . GLY A 1 212 ? 149.561 146.612 91.714  1.00 55.99  ? 158 GLY A O   1 
ATOM   1258  N N   . TYR A 1 213 ? 147.690 147.768 92.172  1.00 52.50  ? 159 TYR A N   1 
ATOM   1259  C CA  . TYR A 1 213 ? 148.097 148.939 91.411  1.00 50.65  ? 159 TYR A CA  1 
ATOM   1260  C C   . TYR A 1 213 ? 148.936 149.867 92.277  1.00 52.74  ? 159 TYR A C   1 
ATOM   1261  O O   . TYR A 1 213 ? 148.574 150.157 93.421  1.00 57.66  ? 159 TYR A O   1 
ATOM   1262  C CB  . TYR A 1 213 ? 146.877 149.681 90.869  1.00 50.77  ? 159 TYR A CB  1 
ATOM   1263  C CG  . TYR A 1 213 ? 146.109 148.904 89.831  1.00 52.50  ? 159 TYR A CG  1 
ATOM   1264  C CD1 . TYR A 1 213 ? 146.587 148.784 88.536  1.00 55.06  ? 159 TYR A CD1 1 
ATOM   1265  C CD2 . TYR A 1 213 ? 144.904 148.293 90.143  1.00 50.42  ? 159 TYR A CD2 1 
ATOM   1266  C CE1 . TYR A 1 213 ? 145.890 148.076 87.582  1.00 54.91  ? 159 TYR A CE1 1 
ATOM   1267  C CE2 . TYR A 1 213 ? 144.199 147.583 89.194  1.00 52.38  ? 159 TYR A CE2 1 
ATOM   1268  C CZ  . TYR A 1 213 ? 144.698 147.479 87.915  1.00 54.38  ? 159 TYR A CZ  1 
ATOM   1269  O OH  . TYR A 1 213 ? 144.001 146.773 86.962  1.00 57.57  ? 159 TYR A OH  1 
ATOM   1270  N N   . THR A 1 214 ? 150.056 150.329 91.728  1.00 55.22  ? 160 THR A N   1 
ATOM   1271  C CA  . THR A 1 214 ? 150.929 151.259 92.420  1.00 58.11  ? 160 THR A CA  1 
ATOM   1272  C C   . THR A 1 214 ? 150.435 152.689 92.215  1.00 59.07  ? 160 THR A C   1 
ATOM   1273  O O   . THR A 1 214 ? 149.391 152.933 91.607  1.00 61.16  ? 160 THR A O   1 
ATOM   1274  C CB  . THR A 1 214 ? 152.370 151.104 91.936  1.00 57.00  ? 160 THR A CB  1 
ATOM   1275  O OG1 . THR A 1 214 ? 152.447 151.443 90.546  1.00 62.20  ? 160 THR A OG1 1 
ATOM   1276  C CG2 . THR A 1 214 ? 152.845 149.675 92.127  1.00 59.26  ? 160 THR A CG2 1 
ATOM   1277  N N   . THR A 1 215 ? 151.197 153.655 92.734  1.00 59.37  ? 161 THR A N   1 
ATOM   1278  C CA  . THR A 1 215 ? 150.853 155.055 92.523  1.00 60.30  ? 161 THR A CA  1 
ATOM   1279  C C   . THR A 1 215 ? 150.997 155.469 91.066  1.00 64.09  ? 161 THR A C   1 
ATOM   1280  O O   . THR A 1 215 ? 150.388 156.463 90.655  1.00 68.35  ? 161 THR A O   1 
ATOM   1281  C CB  . THR A 1 215 ? 151.719 155.958 93.400  1.00 63.51  ? 161 THR A CB  1 
ATOM   1282  O OG1 . THR A 1 215 ? 153.103 155.706 93.128  1.00 67.88  ? 161 THR A OG1 1 
ATOM   1283  C CG2 . THR A 1 215 ? 151.437 155.697 94.868  1.00 61.91  ? 161 THR A CG2 1 
ATOM   1284  N N   . ASP A 1 216 ? 151.791 154.740 90.281  1.00 65.63  ? 162 ASP A N   1 
ATOM   1285  C CA  . ASP A 1 216 ? 151.885 155.024 88.856  1.00 64.89  ? 162 ASP A CA  1 
ATOM   1286  C C   . ASP A 1 216 ? 150.618 154.631 88.111  1.00 62.20  ? 162 ASP A C   1 
ATOM   1287  O O   . ASP A 1 216 ? 150.386 155.128 87.004  1.00 67.27  ? 162 ASP A O   1 
ATOM   1288  C CB  . ASP A 1 216 ? 153.086 154.300 88.246  1.00 67.72  ? 162 ASP A CB  1 
ATOM   1289  C CG  . ASP A 1 216 ? 154.383 154.606 88.969  1.00 80.34  ? 162 ASP A CG  1 
ATOM   1290  O OD1 . ASP A 1 216 ? 154.485 155.685 89.589  1.00 82.03  ? 162 ASP A OD1 1 
ATOM   1291  O OD2 . ASP A 1 216 ? 155.306 153.765 88.913  1.00 82.30  ? 162 ASP A OD2 1 
ATOM   1292  N N   . ASP A 1 217 ? 149.799 153.754 88.688  1.00 59.49  ? 163 ASP A N   1 
ATOM   1293  C CA  . ASP A 1 217 ? 148.604 153.254 88.025  1.00 61.04  ? 163 ASP A CA  1 
ATOM   1294  C C   . ASP A 1 217 ? 147.305 153.755 88.631  1.00 58.92  ? 163 ASP A C   1 
ATOM   1295  O O   . ASP A 1 217 ? 146.303 153.834 87.920  1.00 63.53  ? 163 ASP A O   1 
ATOM   1296  C CB  . ASP A 1 217 ? 148.590 151.719 88.041  1.00 63.51  ? 163 ASP A CB  1 
ATOM   1297  C CG  . ASP A 1 217 ? 149.797 151.117 87.351  1.00 71.29  ? 163 ASP A CG  1 
ATOM   1298  O OD1 . ASP A 1 217 ? 150.598 151.882 86.777  1.00 75.80  ? 163 ASP A OD1 1 
ATOM   1299  O OD2 . ASP A 1 217 ? 149.945 149.878 87.384  1.00 70.03  ? 163 ASP A OD2 1 
ATOM   1300  N N   . ILE A 1 218 ? 147.291 154.100 89.918  1.00 56.27  ? 164 ILE A N   1 
ATOM   1301  C CA  . ILE A 1 218 ? 146.064 154.518 90.582  1.00 53.08  ? 164 ILE A CA  1 
ATOM   1302  C C   . ILE A 1 218 ? 146.417 155.501 91.688  1.00 54.60  ? 164 ILE A C   1 
ATOM   1303  O O   . ILE A 1 218 ? 147.514 155.463 92.251  1.00 58.70  ? 164 ILE A O   1 
ATOM   1304  C CB  . ILE A 1 218 ? 145.279 153.303 91.133  1.00 49.48  ? 164 ILE A CB  1 
ATOM   1305  C CG1 . ILE A 1 218 ? 143.811 153.663 91.350  1.00 47.00  ? 164 ILE A CG1 1 
ATOM   1306  C CG2 . ILE A 1 218 ? 145.897 152.803 92.429  1.00 53.13  ? 164 ILE A CG2 1 
ATOM   1307  C CD1 . ILE A 1 218 ? 142.955 152.487 91.754  1.00 51.94  ? 164 ILE A CD1 1 
ATOM   1308  N N   . GLU A 1 219 ? 145.484 156.405 91.977  1.00 52.22  ? 165 GLU A N   1 
ATOM   1309  C CA  . GLU A 1 219 ? 145.638 157.375 93.051  1.00 52.16  ? 165 GLU A CA  1 
ATOM   1310  C C   . GLU A 1 219 ? 144.319 157.504 93.795  1.00 50.99  ? 165 GLU A C   1 
ATOM   1311  O O   . GLU A 1 219 ? 143.248 157.457 93.184  1.00 49.15  ? 165 GLU A O   1 
ATOM   1312  C CB  . GLU A 1 219 ? 146.080 158.742 92.516  1.00 55.83  ? 165 GLU A CB  1 
ATOM   1313  C CG  . GLU A 1 219 ? 147.485 158.758 91.943  1.00 58.07  ? 165 GLU A CG  1 
ATOM   1314  C CD  . GLU A 1 219 ? 147.823 160.066 91.257  1.00 68.78  ? 165 GLU A CD  1 
ATOM   1315  O OE1 . GLU A 1 219 ? 146.900 160.877 91.032  1.00 72.96  ? 165 GLU A OE1 1 
ATOM   1316  O OE2 . GLU A 1 219 ? 149.011 160.284 90.942  1.00 69.72  ? 165 GLU A OE2 1 
ATOM   1317  N N   . PHE A 1 220 ? 144.402 157.672 95.110  1.00 47.99  ? 166 PHE A N   1 
ATOM   1318  C CA  . PHE A 1 220 ? 143.230 157.775 95.964  1.00 45.02  ? 166 PHE A CA  1 
ATOM   1319  C C   . PHE A 1 220 ? 143.107 159.178 96.539  1.00 45.03  ? 166 PHE A C   1 
ATOM   1320  O O   . PHE A 1 220 ? 144.106 159.857 96.791  1.00 51.70  ? 166 PHE A O   1 
ATOM   1321  C CB  . PHE A 1 220 ? 143.289 156.766 97.115  1.00 46.09  ? 166 PHE A CB  1 
ATOM   1322  C CG  . PHE A 1 220 ? 143.066 155.344 96.693  1.00 43.80  ? 166 PHE A CG  1 
ATOM   1323  C CD1 . PHE A 1 220 ? 142.584 155.047 95.433  1.00 47.41  ? 166 PHE A CD1 1 
ATOM   1324  C CD2 . PHE A 1 220 ? 143.331 154.304 97.567  1.00 42.31  ? 166 PHE A CD2 1 
ATOM   1325  C CE1 . PHE A 1 220 ? 142.379 153.740 95.049  1.00 47.01  ? 166 PHE A CE1 1 
ATOM   1326  C CE2 . PHE A 1 220 ? 143.126 152.996 97.188  1.00 42.97  ? 166 PHE A CE2 1 
ATOM   1327  C CZ  . PHE A 1 220 ? 142.650 152.713 95.927  1.00 43.96  ? 166 PHE A CZ  1 
ATOM   1328  N N   . TYR A 1 221 ? 141.864 159.607 96.743  1.00 42.23  ? 167 TYR A N   1 
ATOM   1329  C CA  . TYR A 1 221 ? 141.589 160.828 97.484  1.00 43.45  ? 167 TYR A CA  1 
ATOM   1330  C C   . TYR A 1 221 ? 140.205 160.720 98.104  1.00 44.85  ? 167 TYR A C   1 
ATOM   1331  O O   . TYR A 1 221 ? 139.362 159.938 97.659  1.00 48.20  ? 167 TYR A O   1 
ATOM   1332  C CB  . TYR A 1 221 ? 141.698 162.078 96.599  1.00 44.55  ? 167 TYR A CB  1 
ATOM   1333  C CG  . TYR A 1 221 ? 140.653 162.186 95.511  1.00 44.71  ? 167 TYR A CG  1 
ATOM   1334  C CD1 . TYR A 1 221 ? 139.454 162.847 95.737  1.00 46.17  ? 167 TYR A CD1 1 
ATOM   1335  C CD2 . TYR A 1 221 ? 140.874 161.648 94.253  1.00 46.40  ? 167 TYR A CD2 1 
ATOM   1336  C CE1 . TYR A 1 221 ? 138.501 162.955 94.747  1.00 45.86  ? 167 TYR A CE1 1 
ATOM   1337  C CE2 . TYR A 1 221 ? 139.927 161.752 93.257  1.00 50.32  ? 167 TYR A CE2 1 
ATOM   1338  C CZ  . TYR A 1 221 ? 138.742 162.407 93.510  1.00 51.55  ? 167 TYR A CZ  1 
ATOM   1339  O OH  . TYR A 1 221 ? 137.793 162.514 92.520  1.00 62.18  ? 167 TYR A OH  1 
ATOM   1340  N N   . TRP A 1 222 ? 139.982 161.512 99.149  1.00 42.11  ? 168 TRP A N   1 
ATOM   1341  C CA  . TRP A 1 222 ? 138.687 161.567 99.821  1.00 40.62  ? 168 TRP A CA  1 
ATOM   1342  C C   . TRP A 1 222 ? 137.812 162.559 99.069  1.00 46.37  ? 168 TRP A C   1 
ATOM   1343  O O   . TRP A 1 222 ? 137.998 163.773 99.173  1.00 50.96  ? 168 TRP A O   1 
ATOM   1344  C CB  . TRP A 1 222 ? 138.845 161.964 101.283 1.00 40.09  ? 168 TRP A CB  1 
ATOM   1345  C CG  . TRP A 1 222 ? 139.447 160.904 102.147 1.00 41.03  ? 168 TRP A CG  1 
ATOM   1346  C CD1 . TRP A 1 222 ? 140.720 160.867 102.629 1.00 41.44  ? 168 TRP A CD1 1 
ATOM   1347  C CD2 . TRP A 1 222 ? 138.796 159.728 102.641 1.00 41.56  ? 168 TRP A CD2 1 
ATOM   1348  N NE1 . TRP A 1 222 ? 140.905 159.741 103.391 1.00 39.99  ? 168 TRP A NE1 1 
ATOM   1349  C CE2 . TRP A 1 222 ? 139.739 159.024 103.414 1.00 40.99  ? 168 TRP A CE2 1 
ATOM   1350  C CE3 . TRP A 1 222 ? 137.509 159.201 102.503 1.00 42.03  ? 168 TRP A CE3 1 
ATOM   1351  C CZ2 . TRP A 1 222 ? 139.435 157.823 104.047 1.00 41.94  ? 168 TRP A CZ2 1 
ATOM   1352  C CZ3 . TRP A 1 222 ? 137.211 158.009 103.131 1.00 40.43  ? 168 TRP A CZ3 1 
ATOM   1353  C CH2 . TRP A 1 222 ? 138.169 157.333 103.894 1.00 39.23  ? 168 TRP A CH2 1 
ATOM   1354  N N   . ARG A 1 223 ? 136.853 162.041 98.309  1.00 47.09  ? 169 ARG A N   1 
ATOM   1355  C CA  . ARG A 1 223 ? 135.971 162.888 97.519  1.00 47.23  ? 169 ARG A CA  1 
ATOM   1356  C C   . ARG A 1 223 ? 135.058 163.683 98.442  1.00 50.91  ? 169 ARG A C   1 
ATOM   1357  O O   . ARG A 1 223 ? 134.273 163.106 99.199  1.00 50.49  ? 169 ARG A O   1 
ATOM   1358  C CB  . ARG A 1 223 ? 135.158 162.036 96.552  1.00 49.21  ? 169 ARG A CB  1 
ATOM   1359  C CG  . ARG A 1 223 ? 134.130 162.799 95.750  1.00 50.79  ? 169 ARG A CG  1 
ATOM   1360  C CD  . ARG A 1 223 ? 133.621 161.950 94.605  1.00 57.43  ? 169 ARG A CD  1 
ATOM   1361  N NE  . ARG A 1 223 ? 132.452 162.537 93.964  1.00 66.69  ? 169 ARG A NE  1 
ATOM   1362  C CZ  . ARG A 1 223 ? 131.202 162.191 94.233  1.00 67.47  ? 169 ARG A CZ  1 
ATOM   1363  N NH1 . ARG A 1 223 ? 130.922 161.253 95.122  1.00 60.72  ? 169 ARG A NH1 1 
ATOM   1364  N NH2 . ARG A 1 223 ? 130.208 162.796 93.590  1.00 67.51  ? 169 ARG A NH2 1 
ATOM   1365  N N   . GLY A 1 224 ? 135.160 165.005 98.378  1.00 53.30  ? 170 GLY A N   1 
ATOM   1366  C CA  . GLY A 1 224 ? 134.453 165.872 99.292  1.00 54.56  ? 170 GLY A CA  1 
ATOM   1367  C C   . GLY A 1 224 ? 135.285 166.416 100.431 1.00 57.10  ? 170 GLY A C   1 
ATOM   1368  O O   . GLY A 1 224 ? 134.732 167.083 101.313 1.00 62.61  ? 170 GLY A O   1 
ATOM   1369  N N   . GLY A 1 225 ? 136.591 166.160 100.439 1.00 53.88  ? 171 GLY A N   1 
ATOM   1370  C CA  . GLY A 1 225 ? 137.438 166.686 101.497 1.00 59.65  ? 171 GLY A CA  1 
ATOM   1371  C C   . GLY A 1 225 ? 137.145 166.027 102.830 1.00 60.32  ? 171 GLY A C   1 
ATOM   1372  O O   . GLY A 1 225 ? 136.909 164.818 102.920 1.00 57.87  ? 171 GLY A O   1 
ATOM   1373  N N   . ASP A 1 226 ? 137.163 166.838 103.889 1.00 65.57  ? 172 ASP A N   1 
ATOM   1374  C CA  . ASP A 1 226 ? 136.897 166.341 105.234 1.00 68.07  ? 172 ASP A CA  1 
ATOM   1375  C C   . ASP A 1 226 ? 135.455 165.893 105.424 1.00 62.82  ? 172 ASP A C   1 
ATOM   1376  O O   . ASP A 1 226 ? 135.152 165.257 106.439 1.00 63.57  ? 172 ASP A O   1 
ATOM   1377  C CB  . ASP A 1 226 ? 137.246 167.414 106.266 1.00 75.26  ? 172 ASP A CB  1 
ATOM   1378  C CG  . ASP A 1 226 ? 138.716 167.784 106.247 1.00 85.51  ? 172 ASP A CG  1 
ATOM   1379  O OD1 . ASP A 1 226 ? 139.496 167.094 105.558 1.00 87.27  ? 172 ASP A OD1 1 
ATOM   1380  O OD2 . ASP A 1 226 ? 139.092 168.768 106.917 1.00 90.44  ? 172 ASP A OD2 1 
ATOM   1381  N N   . LYS A 1 227 ? 134.567 166.203 104.484 1.00 57.22  ? 173 LYS A N   1 
ATOM   1382  C CA  . LYS A 1 227 ? 133.173 165.795 104.556 1.00 59.09  ? 173 LYS A CA  1 
ATOM   1383  C C   . LYS A 1 227 ? 132.908 164.492 103.815 1.00 59.45  ? 173 LYS A C   1 
ATOM   1384  O O   . LYS A 1 227 ? 131.743 164.150 103.584 1.00 59.82  ? 173 LYS A O   1 
ATOM   1385  C CB  . LYS A 1 227 ? 132.275 166.901 103.999 1.00 63.90  ? 173 LYS A CB  1 
ATOM   1386  C CG  . LYS A 1 227 ? 132.549 168.270 104.591 1.00 67.77  ? 173 LYS A CG  1 
ATOM   1387  C CD  . LYS A 1 227 ? 131.612 169.313 104.015 1.00 74.37  ? 173 LYS A CD  1 
ATOM   1388  C CE  . LYS A 1 227 ? 131.924 170.696 104.560 1.00 78.12  ? 173 LYS A CE  1 
ATOM   1389  N NZ  . LYS A 1 227 ? 130.949 171.710 104.076 1.00 83.73  ? 173 LYS A NZ  1 
ATOM   1390  N N   . ALA A 1 228 ? 133.960 163.765 103.432 1.00 55.82  ? 174 ALA A N   1 
ATOM   1391  C CA  . ALA A 1 228 ? 133.779 162.531 102.674 1.00 48.73  ? 174 ALA A CA  1 
ATOM   1392  C C   . ALA A 1 228 ? 133.042 161.476 103.490 1.00 49.29  ? 174 ALA A C   1 
ATOM   1393  O O   . ALA A 1 228 ? 132.173 160.771 102.964 1.00 50.50  ? 174 ALA A O   1 
ATOM   1394  C CB  . ALA A 1 228 ? 135.132 162.001 102.207 1.00 46.25  ? 174 ALA A CB  1 
ATOM   1395  N N   . VAL A 1 229 ? 133.371 161.350 104.772 1.00 51.35  ? 175 VAL A N   1 
ATOM   1396  C CA  . VAL A 1 229 ? 132.761 160.354 105.645 1.00 48.95  ? 175 VAL A CA  1 
ATOM   1397  C C   . VAL A 1 229 ? 131.628 161.016 106.415 1.00 53.14  ? 175 VAL A C   1 
ATOM   1398  O O   . VAL A 1 229 ? 131.848 161.988 107.146 1.00 58.00  ? 175 VAL A O   1 
ATOM   1399  C CB  . VAL A 1 229 ? 133.792 159.737 106.602 1.00 44.93  ? 175 VAL A CB  1 
ATOM   1400  C CG1 . VAL A 1 229 ? 133.102 158.813 107.588 1.00 46.84  ? 175 VAL A CG1 1 
ATOM   1401  C CG2 . VAL A 1 229 ? 134.849 158.984 105.819 1.00 42.71  ? 175 VAL A CG2 1 
ATOM   1402  N N   . THR A 1 230 ? 130.417 160.490 106.255 1.00 51.22  ? 176 THR A N   1 
ATOM   1403  C CA  . THR A 1 230 ? 129.230 161.010 106.915 1.00 57.32  ? 176 THR A CA  1 
ATOM   1404  C C   . THR A 1 230 ? 128.646 159.948 107.837 1.00 57.97  ? 176 THR A C   1 
ATOM   1405  O O   . THR A 1 230 ? 129.041 158.780 107.810 1.00 58.65  ? 176 THR A O   1 
ATOM   1406  C CB  . THR A 1 230 ? 128.174 161.458 105.896 1.00 60.43  ? 176 THR A CB  1 
ATOM   1407  O OG1 . THR A 1 230 ? 127.503 160.310 105.364 1.00 62.33  ? 176 THR A OG1 1 
ATOM   1408  C CG2 . THR A 1 230 ? 128.824 162.228 104.757 1.00 60.38  ? 176 THR A CG2 1 
ATOM   1409  N N   . GLY A 1 231 ? 127.690 160.370 108.661 1.00 61.94  ? 177 GLY A N   1 
ATOM   1410  C CA  . GLY A 1 231 ? 127.019 159.458 109.562 1.00 65.76  ? 177 GLY A CA  1 
ATOM   1411  C C   . GLY A 1 231 ? 127.740 159.182 110.859 1.00 67.92  ? 177 GLY A C   1 
ATOM   1412  O O   . GLY A 1 231 ? 127.292 158.321 111.623 1.00 68.65  ? 177 GLY A O   1 
ATOM   1413  N N   . VAL A 1 232 ? 128.843 159.878 111.133 1.00 68.03  ? 178 VAL A N   1 
ATOM   1414  C CA  . VAL A 1 232 ? 129.578 159.643 112.371 1.00 65.30  ? 178 VAL A CA  1 
ATOM   1415  C C   . VAL A 1 232 ? 128.769 160.112 113.573 1.00 68.42  ? 178 VAL A C   1 
ATOM   1416  O O   . VAL A 1 232 ? 128.777 159.472 114.631 1.00 68.37  ? 178 VAL A O   1 
ATOM   1417  C CB  . VAL A 1 232 ? 130.956 160.325 112.313 1.00 63.38  ? 178 VAL A CB  1 
ATOM   1418  C CG1 . VAL A 1 232 ? 131.758 159.997 113.558 1.00 60.88  ? 178 VAL A CG1 1 
ATOM   1419  C CG2 . VAL A 1 232 ? 131.705 159.898 111.065 1.00 63.32  ? 178 VAL A CG2 1 
ATOM   1420  N N   . GLU A 1 233 ? 128.058 161.233 113.435 1.00 73.36  ? 179 GLU A N   1 
ATOM   1421  C CA  . GLU A 1 233 ? 127.281 161.770 114.546 1.00 76.19  ? 179 GLU A CA  1 
ATOM   1422  C C   . GLU A 1 233 ? 126.028 160.957 114.841 1.00 75.89  ? 179 GLU A C   1 
ATOM   1423  O O   . GLU A 1 233 ? 125.396 161.184 115.878 1.00 77.82  ? 179 GLU A O   1 
ATOM   1424  C CB  . GLU A 1 233 ? 126.892 163.224 114.271 1.00 78.37  ? 179 GLU A CB  1 
ATOM   1425  C CG  . GLU A 1 233 ? 125.914 163.412 113.119 1.00 83.09  ? 179 GLU A CG  1 
ATOM   1426  C CD  . GLU A 1 233 ? 126.594 163.408 111.766 1.00 83.16  ? 179 GLU A CD  1 
ATOM   1427  O OE1 . GLU A 1 233 ? 127.842 163.391 111.729 1.00 83.53  ? 179 GLU A OE1 1 
ATOM   1428  O OE2 . GLU A 1 233 ? 125.883 163.423 110.739 1.00 81.96  ? 179 GLU A OE2 1 
ATOM   1429  N N   . ARG A 1 234 ? 125.654 160.029 113.966 1.00 73.04  ? 180 ARG A N   1 
ATOM   1430  C CA  . ARG A 1 234 ? 124.468 159.198 114.140 1.00 74.07  ? 180 ARG A CA  1 
ATOM   1431  C C   . ARG A 1 234 ? 124.842 157.761 114.492 1.00 78.64  ? 180 ARG A C   1 
ATOM   1432  O O   . ARG A 1 234 ? 124.181 156.810 114.072 1.00 83.50  ? 180 ARG A O   1 
ATOM   1433  C CB  . ARG A 1 234 ? 123.600 159.233 112.887 1.00 75.39  ? 180 ARG A CB  1 
ATOM   1434  C CG  . ARG A 1 234 ? 123.192 160.632 112.456 1.00 78.39  ? 180 ARG A CG  1 
ATOM   1435  C CD  . ARG A 1 234 ? 122.399 160.614 111.158 1.00 83.46  ? 180 ARG A CD  1 
ATOM   1436  N NE  . ARG A 1 234 ? 123.186 160.120 110.033 1.00 88.81  ? 180 ARG A NE  1 
ATOM   1437  C CZ  . ARG A 1 234 ? 123.099 158.893 109.536 1.00 90.63  ? 180 ARG A CZ  1 
ATOM   1438  N NH1 . ARG A 1 234 ? 122.261 158.001 110.039 1.00 91.48  ? 180 ARG A NH1 1 
ATOM   1439  N NH2 . ARG A 1 234 ? 123.871 158.554 108.508 1.00 85.13  ? 180 ARG A NH2 1 
ATOM   1440  N N   . ILE A 1 235 ? 125.908 157.589 115.269 1.00 78.39  ? 181 ILE A N   1 
ATOM   1441  C CA  . ILE A 1 235 ? 126.402 156.277 115.669 1.00 76.88  ? 181 ILE A CA  1 
ATOM   1442  C C   . ILE A 1 235 ? 126.127 156.101 117.154 1.00 76.05  ? 181 ILE A C   1 
ATOM   1443  O O   . ILE A 1 235 ? 126.556 156.923 117.973 1.00 78.75  ? 181 ILE A O   1 
ATOM   1444  C CB  . ILE A 1 235 ? 127.899 156.117 115.369 1.00 72.12  ? 181 ILE A CB  1 
ATOM   1445  C CG1 . ILE A 1 235 ? 128.142 156.101 113.862 1.00 68.33  ? 181 ILE A CG1 1 
ATOM   1446  C CG2 . ILE A 1 235 ? 128.440 154.851 116.015 1.00 65.34  ? 181 ILE A CG2 1 
ATOM   1447  C CD1 . ILE A 1 235 ? 129.597 155.997 113.490 1.00 64.07  ? 181 ILE A CD1 1 
ATOM   1448  N N   . GLU A 1 236 ? 125.414 155.035 117.501 1.00 75.64  ? 182 GLU A N   1 
ATOM   1449  C CA  . GLU A 1 236 ? 125.071 154.733 118.888 1.00 78.69  ? 182 GLU A CA  1 
ATOM   1450  C C   . GLU A 1 236 ? 125.878 153.525 119.350 1.00 76.16  ? 182 GLU A C   1 
ATOM   1451  O O   . GLU A 1 236 ? 125.502 152.379 119.093 1.00 77.15  ? 182 GLU A O   1 
ATOM   1452  C CB  . GLU A 1 236 ? 123.574 154.488 119.041 1.00 85.57  ? 182 GLU A CB  1 
ATOM   1453  C CG  . GLU A 1 236 ? 122.741 155.753 119.030 1.00 92.82  ? 182 GLU A CG  1 
ATOM   1454  C CD  . GLU A 1 236 ? 121.526 155.647 119.927 1.00 102.73 ? 182 GLU A CD  1 
ATOM   1455  O OE1 . GLU A 1 236 ? 121.257 154.537 120.431 1.00 104.05 ? 182 GLU A OE1 1 
ATOM   1456  O OE2 . GLU A 1 236 ? 120.846 156.674 120.135 1.00 104.64 ? 182 GLU A OE2 1 
ATOM   1457  N N   . LEU A 1 237 ? 126.991 153.790 120.032 1.00 74.97  ? 183 LEU A N   1 
ATOM   1458  C CA  . LEU A 1 237 ? 127.733 152.752 120.728 1.00 75.30  ? 183 LEU A CA  1 
ATOM   1459  C C   . LEU A 1 237 ? 127.328 152.764 122.190 1.00 73.95  ? 183 LEU A C   1 
ATOM   1460  O O   . LEU A 1 237 ? 127.547 153.778 122.870 1.00 71.74  ? 183 LEU A O   1 
ATOM   1461  C CB  . LEU A 1 237 ? 129.234 152.974 120.591 1.00 71.86  ? 183 LEU A CB  1 
ATOM   1462  C CG  . LEU A 1 237 ? 129.865 152.521 119.274 1.00 62.63  ? 183 LEU A CG  1 
ATOM   1463  C CD1 . LEU A 1 237 ? 131.324 152.930 119.207 1.00 59.37  ? 183 LEU A CD1 1 
ATOM   1464  C CD2 . LEU A 1 237 ? 129.727 151.019 119.122 1.00 59.75  ? 183 LEU A CD2 1 
ATOM   1465  N N   . PRO A 1 238 ? 126.723 151.693 122.710 1.00 71.87  ? 184 PRO A N   1 
ATOM   1466  C CA  . PRO A 1 238 ? 126.229 151.739 124.097 1.00 68.53  ? 184 PRO A CA  1 
ATOM   1467  C C   . PRO A 1 238 ? 127.306 152.040 125.124 1.00 67.90  ? 184 PRO A C   1 
ATOM   1468  O O   . PRO A 1 238 ? 127.051 152.787 126.076 1.00 73.52  ? 184 PRO A O   1 
ATOM   1469  C CB  . PRO A 1 238 ? 125.630 150.338 124.296 1.00 72.46  ? 184 PRO A CB  1 
ATOM   1470  C CG  . PRO A 1 238 ? 125.316 149.860 122.914 1.00 76.65  ? 184 PRO A CG  1 
ATOM   1471  C CD  . PRO A 1 238 ? 126.399 150.420 122.046 1.00 74.63  ? 184 PRO A CD  1 
ATOM   1472  N N   . GLN A 1 239 ? 128.505 151.491 124.958 1.00 67.75  ? 185 GLN A N   1 
ATOM   1473  C CA  . GLN A 1 239 ? 129.570 151.652 125.937 1.00 66.34  ? 185 GLN A CA  1 
ATOM   1474  C C   . GLN A 1 239 ? 130.625 152.668 125.515 1.00 67.50  ? 185 GLN A C   1 
ATOM   1475  O O   . GLN A 1 239 ? 131.575 152.901 126.268 1.00 69.01  ? 185 GLN A O   1 
ATOM   1476  C CB  . GLN A 1 239 ? 130.234 150.298 126.210 1.00 65.68  ? 185 GLN A CB  1 
ATOM   1477  C CG  . GLN A 1 239 ? 130.942 150.200 127.552 1.00 72.24  ? 185 GLN A CG  1 
ATOM   1478  C CD  . GLN A 1 239 ? 131.802 148.959 127.665 1.00 74.63  ? 185 GLN A CD  1 
ATOM   1479  O OE1 . GLN A 1 239 ? 132.649 148.856 128.551 1.00 68.03  ? 185 GLN A OE1 1 
ATOM   1480  N NE2 . GLN A 1 239 ? 131.591 148.009 126.762 1.00 76.56  ? 185 GLN A NE2 1 
ATOM   1481  N N   . PHE A 1 240 ? 130.480 153.288 124.348 1.00 69.57  ? 186 PHE A N   1 
ATOM   1482  C CA  . PHE A 1 240 ? 131.496 154.189 123.826 1.00 66.75  ? 186 PHE A CA  1 
ATOM   1483  C C   . PHE A 1 240 ? 130.862 155.477 123.324 1.00 68.24  ? 186 PHE A C   1 
ATOM   1484  O O   . PHE A 1 240 ? 129.658 155.550 123.068 1.00 69.62  ? 186 PHE A O   1 
ATOM   1485  C CB  . PHE A 1 240 ? 132.295 153.542 122.688 1.00 64.97  ? 186 PHE A CB  1 
ATOM   1486  C CG  . PHE A 1 240 ? 133.294 152.526 123.148 1.00 64.69  ? 186 PHE A CG  1 
ATOM   1487  C CD1 . PHE A 1 240 ? 134.552 152.919 123.572 1.00 61.16  ? 186 PHE A CD1 1 
ATOM   1488  C CD2 . PHE A 1 240 ? 132.983 151.179 123.147 1.00 63.94  ? 186 PHE A CD2 1 
ATOM   1489  C CE1 . PHE A 1 240 ? 135.476 151.990 123.992 1.00 60.58  ? 186 PHE A CE1 1 
ATOM   1490  C CE2 . PHE A 1 240 ? 133.904 150.244 123.567 1.00 63.53  ? 186 PHE A CE2 1 
ATOM   1491  C CZ  . PHE A 1 240 ? 135.153 150.651 123.990 1.00 62.80  ? 186 PHE A CZ  1 
ATOM   1492  N N   . SER A 1 241 ? 131.701 156.501 123.191 1.00 68.82  ? 187 SER A N   1 
ATOM   1493  C CA  . SER A 1 241 ? 131.325 157.760 122.569 1.00 69.04  ? 187 SER A CA  1 
ATOM   1494  C C   . SER A 1 241 ? 132.413 158.159 121.584 1.00 66.75  ? 187 SER A C   1 
ATOM   1495  O O   . SER A 1 241 ? 133.603 157.972 121.854 1.00 68.88  ? 187 SER A O   1 
ATOM   1496  C CB  . SER A 1 241 ? 131.121 158.866 123.610 1.00 69.86  ? 187 SER A CB  1 
ATOM   1497  O OG  . SER A 1 241 ? 132.320 159.131 124.315 1.00 73.63  ? 187 SER A OG  1 
ATOM   1498  N N   . ILE A 1 242 ? 132.004 158.709 120.444 1.00 60.04  ? 188 ILE A N   1 
ATOM   1499  C CA  . ILE A 1 242 ? 132.932 159.076 119.381 1.00 61.13  ? 188 ILE A CA  1 
ATOM   1500  C C   . ILE A 1 242 ? 133.401 160.501 119.655 1.00 61.84  ? 188 ILE A C   1 
ATOM   1501  O O   . ILE A 1 242 ? 132.678 161.467 119.408 1.00 63.60  ? 188 ILE A O   1 
ATOM   1502  C CB  . ILE A 1 242 ? 132.294 158.941 117.999 1.00 64.77  ? 188 ILE A CB  1 
ATOM   1503  C CG1 . ILE A 1 242 ? 131.813 157.507 117.782 1.00 63.47  ? 188 ILE A CG1 1 
ATOM   1504  C CG2 . ILE A 1 242 ? 133.281 159.346 116.915 1.00 67.01  ? 188 ILE A CG2 1 
ATOM   1505  C CD1 . ILE A 1 242 ? 131.357 157.225 116.377 1.00 67.48  ? 188 ILE A CD1 1 
ATOM   1506  N N   . VAL A 1 243 ? 134.622 160.628 120.176 1.00 63.52  ? 189 VAL A N   1 
ATOM   1507  C CA  . VAL A 1 243 ? 135.181 161.946 120.459 1.00 64.63  ? 189 VAL A CA  1 
ATOM   1508  C C   . VAL A 1 243 ? 135.480 162.692 119.164 1.00 69.67  ? 189 VAL A C   1 
ATOM   1509  O O   . VAL A 1 243 ? 135.126 163.865 119.009 1.00 76.39  ? 189 VAL A O   1 
ATOM   1510  C CB  . VAL A 1 243 ? 136.437 161.815 121.338 1.00 66.87  ? 189 VAL A CB  1 
ATOM   1511  C CG1 . VAL A 1 243 ? 137.095 163.171 121.535 1.00 67.64  ? 189 VAL A CG1 1 
ATOM   1512  C CG2 . VAL A 1 243 ? 136.083 161.189 122.676 1.00 70.48  ? 189 VAL A CG2 1 
ATOM   1513  N N   . GLU A 1 244 ? 136.132 162.024 118.215 1.00 67.50  ? 190 GLU A N   1 
ATOM   1514  C CA  . GLU A 1 244 ? 136.541 162.673 116.978 1.00 67.47  ? 190 GLU A CA  1 
ATOM   1515  C C   . GLU A 1 244 ? 136.776 161.609 115.916 1.00 68.94  ? 190 GLU A C   1 
ATOM   1516  O O   . GLU A 1 244 ? 136.955 160.429 116.223 1.00 70.70  ? 190 GLU A O   1 
ATOM   1517  C CB  . GLU A 1 244 ? 137.806 163.516 117.186 1.00 71.56  ? 190 GLU A CB  1 
ATOM   1518  C CG  . GLU A 1 244 ? 138.125 164.480 116.055 1.00 79.19  ? 190 GLU A CG  1 
ATOM   1519  C CD  . GLU A 1 244 ? 139.588 164.874 116.020 1.00 88.05  ? 190 GLU A CD  1 
ATOM   1520  O OE1 . GLU A 1 244 ? 140.353 164.407 116.890 1.00 88.56  ? 190 GLU A OE1 1 
ATOM   1521  O OE2 . GLU A 1 244 ? 139.975 165.646 115.117 1.00 86.57  ? 190 GLU A OE2 1 
ATOM   1522  N N   . HIS A 1 245 ? 136.770 162.046 114.657 1.00 68.06  ? 191 HIS A N   1 
ATOM   1523  C CA  . HIS A 1 245 ? 137.161 161.202 113.538 1.00 63.41  ? 191 HIS A CA  1 
ATOM   1524  C C   . HIS A 1 245 ? 138.003 162.022 112.570 1.00 63.33  ? 191 HIS A C   1 
ATOM   1525  O O   . HIS A 1 245 ? 137.779 163.221 112.388 1.00 69.26  ? 191 HIS A O   1 
ATOM   1526  C CB  . HIS A 1 245 ? 135.945 160.600 112.819 1.00 55.35  ? 191 HIS A CB  1 
ATOM   1527  C CG  . HIS A 1 245 ? 135.206 161.574 111.957 1.00 58.81  ? 191 HIS A CG  1 
ATOM   1528  N ND1 . HIS A 1 245 ? 134.222 162.405 112.446 1.00 63.81  ? 191 HIS A ND1 1 
ATOM   1529  C CD2 . HIS A 1 245 ? 135.299 161.840 110.632 1.00 60.41  ? 191 HIS A CD2 1 
ATOM   1530  C CE1 . HIS A 1 245 ? 133.744 163.145 111.462 1.00 64.44  ? 191 HIS A CE1 1 
ATOM   1531  N NE2 . HIS A 1 245 ? 134.380 162.822 110.350 1.00 62.97  ? 191 HIS A NE2 1 
ATOM   1532  N N   . ARG A 1 246 ? 138.978 161.359 111.954 1.00 59.32  ? 192 ARG A N   1 
ATOM   1533  C CA  . ARG A 1 246 ? 139.935 162.006 111.069 1.00 53.84  ? 192 ARG A CA  1 
ATOM   1534  C C   . ARG A 1 246 ? 140.116 161.202 109.791 1.00 56.12  ? 192 ARG A C   1 
ATOM   1535  O O   . ARG A 1 246 ? 139.978 159.975 109.780 1.00 58.29  ? 192 ARG A O   1 
ATOM   1536  C CB  . ARG A 1 246 ? 141.297 162.185 111.745 1.00 54.22  ? 192 ARG A CB  1 
ATOM   1537  C CG  . ARG A 1 246 ? 141.328 163.268 112.798 1.00 70.54  ? 192 ARG A CG  1 
ATOM   1538  C CD  . ARG A 1 246 ? 142.705 163.373 113.419 1.00 78.41  ? 192 ARG A CD  1 
ATOM   1539  N NE  . ARG A 1 246 ? 142.802 164.498 114.339 1.00 83.49  ? 192 ARG A NE  1 
ATOM   1540  C CZ  . ARG A 1 246 ? 143.898 164.819 115.012 1.00 85.99  ? 192 ARG A CZ  1 
ATOM   1541  N NH1 . ARG A 1 246 ? 145.011 164.114 114.897 1.00 89.34  ? 192 ARG A NH1 1 
ATOM   1542  N NH2 . ARG A 1 246 ? 143.876 165.875 115.821 1.00 87.77  ? 192 ARG A NH2 1 
ATOM   1543  N N   . LEU A 1 247 ? 140.448 161.918 108.717 1.00 55.30  ? 193 LEU A N   1 
ATOM   1544  C CA  . LEU A 1 247 ? 140.726 161.337 107.410 1.00 48.61  ? 193 LEU A CA  1 
ATOM   1545  C C   . LEU A 1 247 ? 142.168 161.638 107.034 1.00 50.23  ? 193 LEU A C   1 
ATOM   1546  O O   . LEU A 1 247 ? 142.617 162.783 107.151 1.00 57.40  ? 193 LEU A O   1 
ATOM   1547  C CB  . LEU A 1 247 ? 139.787 161.897 106.340 1.00 43.52  ? 193 LEU A CB  1 
ATOM   1548  C CG  . LEU A 1 247 ? 138.306 162.058 106.681 1.00 42.00  ? 193 LEU A CG  1 
ATOM   1549  C CD1 . LEU A 1 247 ? 137.546 162.559 105.469 1.00 45.81  ? 193 LEU A CD1 1 
ATOM   1550  C CD2 . LEU A 1 247 ? 137.726 160.750 107.168 1.00 41.36  ? 193 LEU A CD2 1 
ATOM   1551  N N   . VAL A 1 248 ? 142.886 160.617 106.578 1.00 49.09  ? 194 VAL A N   1 
ATOM   1552  C CA  . VAL A 1 248 ? 144.290 160.734 106.204 1.00 47.99  ? 194 VAL A CA  1 
ATOM   1553  C C   . VAL A 1 248 ? 144.464 160.167 104.803 1.00 52.15  ? 194 VAL A C   1 
ATOM   1554  O O   . VAL A 1 248 ? 143.825 159.174 104.447 1.00 54.69  ? 194 VAL A O   1 
ATOM   1555  C CB  . VAL A 1 248 ? 145.205 160.002 107.209 1.00 51.58  ? 194 VAL A CB  1 
ATOM   1556  C CG1 . VAL A 1 248 ? 146.666 160.162 106.827 1.00 62.85  ? 194 VAL A CG1 1 
ATOM   1557  C CG2 . VAL A 1 248 ? 144.966 160.513 108.621 1.00 56.51  ? 194 VAL A CG2 1 
ATOM   1558  N N   . SER A 1 249 ? 145.318 160.802 104.003 1.00 53.82  ? 195 SER A N   1 
ATOM   1559  C CA  . SER A 1 249 ? 145.667 160.308 102.677 1.00 54.82  ? 195 SER A CA  1 
ATOM   1560  C C   . SER A 1 249 ? 147.179 160.330 102.532 1.00 60.44  ? 195 SER A C   1 
ATOM   1561  O O   . SER A 1 249 ? 147.815 161.340 102.848 1.00 75.44  ? 195 SER A O   1 
ATOM   1562  C CB  . SER A 1 249 ? 145.019 161.157 101.580 1.00 56.84  ? 195 SER A CB  1 
ATOM   1563  O OG  . SER A 1 249 ? 145.353 160.667 100.294 1.00 60.29  ? 195 SER A OG  1 
ATOM   1564  N N   . ARG A 1 250 ? 147.757 159.231 102.052 1.00 54.31  ? 196 ARG A N   1 
ATOM   1565  C CA  . ARG A 1 250 ? 149.209 159.161 101.937 1.00 63.74  ? 196 ARG A CA  1 
ATOM   1566  C C   . ARG A 1 250 ? 149.597 158.053 100.965 1.00 67.05  ? 196 ARG A C   1 
ATOM   1567  O O   . ARG A 1 250 ? 148.744 157.374 100.388 1.00 69.25  ? 196 ARG A O   1 
ATOM   1568  C CB  . ARG A 1 250 ? 149.857 158.948 103.308 1.00 70.73  ? 196 ARG A CB  1 
ATOM   1569  C CG  . ARG A 1 250 ? 149.495 157.637 103.977 1.00 64.41  ? 196 ARG A CG  1 
ATOM   1570  C CD  . ARG A 1 250 ? 149.816 157.684 105.459 1.00 69.35  ? 196 ARG A CD  1 
ATOM   1571  N NE  . ARG A 1 250 ? 149.906 156.353 106.046 1.00 69.25  ? 196 ARG A NE  1 
ATOM   1572  C CZ  . ARG A 1 250 ? 151.042 155.692 106.221 1.00 73.45  ? 196 ARG A CZ  1 
ATOM   1573  N NH1 . ARG A 1 250 ? 152.205 156.213 105.867 1.00 77.08  ? 196 ARG A NH1 1 
ATOM   1574  N NH2 . ARG A 1 250 ? 151.010 154.480 106.766 1.00 72.37  ? 196 ARG A NH2 1 
ATOM   1575  N N   . ASN A 1 251 ? 150.906 157.904 100.766 1.00 66.31  ? 197 ASN A N   1 
ATOM   1576  C CA  . ASN A 1 251 ? 151.491 156.842 99.959  1.00 64.09  ? 197 ASN A CA  1 
ATOM   1577  C C   . ASN A 1 251 ? 152.450 156.039 100.825 1.00 68.64  ? 197 ASN A C   1 
ATOM   1578  O O   . ASN A 1 251 ? 153.146 156.599 101.677 1.00 75.83  ? 197 ASN A O   1 
ATOM   1579  C CB  . ASN A 1 251 ? 152.244 157.403 98.746  1.00 66.08  ? 197 ASN A CB  1 
ATOM   1580  C CG  . ASN A 1 251 ? 151.356 158.216 97.823  1.00 70.31  ? 197 ASN A CG  1 
ATOM   1581  O OD1 . ASN A 1 251 ? 150.249 158.607 98.185  1.00 72.46  ? 197 ASN A OD1 1 
ATOM   1582  N ND2 . ASN A 1 251 ? 151.847 158.482 96.619  1.00 70.25  ? 197 ASN A ND2 1 
ATOM   1583  N N   . VAL A 1 252 ? 152.493 154.728 100.603 1.00 68.87  ? 198 VAL A N   1 
ATOM   1584  C CA  . VAL A 1 252 ? 153.321 153.826 101.395 1.00 70.95  ? 198 VAL A CA  1 
ATOM   1585  C C   . VAL A 1 252 ? 154.192 153.003 100.457 1.00 74.10  ? 198 VAL A C   1 
ATOM   1586  O O   . VAL A 1 252 ? 153.717 152.504 99.433  1.00 72.76  ? 198 VAL A O   1 
ATOM   1587  C CB  . VAL A 1 252 ? 152.465 152.914 102.296 1.00 67.44  ? 198 VAL A CB  1 
ATOM   1588  C CG1 . VAL A 1 252 ? 151.934 153.700 103.477 1.00 60.44  ? 198 VAL A CG1 1 
ATOM   1589  C CG2 . VAL A 1 252 ? 151.314 152.323 101.505 1.00 69.80  ? 198 VAL A CG2 1 
ATOM   1590  N N   . VAL A 1 253 ? 155.466 152.861 100.806 1.00 75.81  ? 199 VAL A N   1 
ATOM   1591  C CA  . VAL A 1 253 ? 156.454 152.231 99.938  1.00 79.90  ? 199 VAL A CA  1 
ATOM   1592  C C   . VAL A 1 253 ? 156.725 150.822 100.449 1.00 82.60  ? 199 VAL A C   1 
ATOM   1593  O O   . VAL A 1 253 ? 157.412 150.639 101.459 1.00 82.09  ? 199 VAL A O   1 
ATOM   1594  C CB  . VAL A 1 253 ? 157.749 153.050 99.872  1.00 78.09  ? 199 VAL A CB  1 
ATOM   1595  C CG1 . VAL A 1 253 ? 158.692 152.467 98.831  1.00 73.02  ? 199 VAL A CG1 1 
ATOM   1596  C CG2 . VAL A 1 253 ? 157.440 154.506 99.570  1.00 74.53  ? 199 VAL A CG2 1 
ATOM   1597  N N   . PHE A 1 254 ? 156.192 149.822 99.751  1.00 83.38  ? 200 PHE A N   1 
ATOM   1598  C CA  . PHE A 1 254 ? 156.552 148.434 99.970  1.00 85.66  ? 200 PHE A CA  1 
ATOM   1599  C C   . PHE A 1 254 ? 157.631 148.030 98.970  1.00 88.84  ? 200 PHE A C   1 
ATOM   1600  O O   . PHE A 1 254 ? 157.993 148.784 98.062  1.00 88.09  ? 200 PHE A O   1 
ATOM   1601  C CB  . PHE A 1 254 ? 155.328 147.525 99.839  1.00 81.48  ? 200 PHE A CB  1 
ATOM   1602  C CG  . PHE A 1 254 ? 154.247 147.818 100.830 1.00 82.10  ? 200 PHE A CG  1 
ATOM   1603  C CD1 . PHE A 1 254 ? 154.307 147.300 102.111 1.00 85.90  ? 200 PHE A CD1 1 
ATOM   1604  C CD2 . PHE A 1 254 ? 153.165 148.605 100.479 1.00 77.75  ? 200 PHE A CD2 1 
ATOM   1605  C CE1 . PHE A 1 254 ? 153.311 147.566 103.026 1.00 88.26  ? 200 PHE A CE1 1 
ATOM   1606  C CE2 . PHE A 1 254 ? 152.166 148.874 101.389 1.00 77.39  ? 200 PHE A CE2 1 
ATOM   1607  C CZ  . PHE A 1 254 ? 152.238 148.354 102.665 1.00 82.46  ? 200 PHE A CZ  1 
ATOM   1608  N N   . ALA A 1 255 ? 158.134 146.803 99.128  1.00 91.14  ? 201 ALA A N   1 
ATOM   1609  C CA  . ALA A 1 255 ? 159.145 146.287 98.215  1.00 94.01  ? 201 ALA A CA  1 
ATOM   1610  C C   . ALA A 1 255 ? 158.652 146.239 96.775  1.00 92.54  ? 201 ALA A C   1 
ATOM   1611  O O   . ALA A 1 255 ? 159.472 146.251 95.850  1.00 92.21  ? 201 ALA A O   1 
ATOM   1612  C CB  . ALA A 1 255 ? 159.593 144.895 98.660  1.00 92.01  ? 201 ALA A CB  1 
ATOM   1613  N N   . THR A 1 256 ? 157.340 146.185 96.563  1.00 90.95  ? 202 THR A N   1 
ATOM   1614  C CA  . THR A 1 256 ? 156.771 146.157 95.223  1.00 87.53  ? 202 THR A CA  1 
ATOM   1615  C C   . THR A 1 256 ? 156.436 147.542 94.681  1.00 81.18  ? 202 THR A C   1 
ATOM   1616  O O   . THR A 1 256 ? 155.896 147.640 93.576  1.00 81.79  ? 202 THR A O   1 
ATOM   1617  C CB  . THR A 1 256 ? 155.513 145.282 95.197  1.00 85.92  ? 202 THR A CB  1 
ATOM   1618  O OG1 . THR A 1 256 ? 154.582 145.747 96.180  1.00 89.62  ? 202 THR A OG1 1 
ATOM   1619  C CG2 . THR A 1 256 ? 155.865 143.831 95.484  1.00 81.14  ? 202 THR A CG2 1 
ATOM   1620  N N   . GLY A 1 257 ? 156.736 148.612 95.421  1.00 78.21  ? 203 GLY A N   1 
ATOM   1621  C CA  . GLY A 1 257 ? 156.525 149.957 94.934  1.00 75.94  ? 203 GLY A CA  1 
ATOM   1622  C C   . GLY A 1 257 ? 155.687 150.769 95.893  1.00 74.78  ? 203 GLY A C   1 
ATOM   1623  O O   . GLY A 1 257 ? 155.442 150.376 97.036  1.00 77.41  ? 203 GLY A O   1 
ATOM   1624  N N   . ALA A 1 258 ? 155.234 151.928 95.424  1.00 70.01  ? 204 ALA A N   1 
ATOM   1625  C CA  . ALA A 1 258 ? 154.448 152.848 96.234  1.00 65.44  ? 204 ALA A CA  1 
ATOM   1626  C C   . ALA A 1 258 ? 152.965 152.646 95.954  1.00 65.87  ? 204 ALA A C   1 
ATOM   1627  O O   . ALA A 1 258 ? 152.549 152.596 94.793  1.00 70.13  ? 204 ALA A O   1 
ATOM   1628  C CB  . ALA A 1 258 ? 154.848 154.297 95.957  1.00 61.96  ? 204 ALA A CB  1 
ATOM   1629  N N   . TYR A 1 259 ? 152.174 152.541 97.019  1.00 62.13  ? 205 TYR A N   1 
ATOM   1630  C CA  . TYR A 1 259 ? 150.745 152.295 96.955  1.00 58.22  ? 205 TYR A CA  1 
ATOM   1631  C C   . TYR A 1 259 ? 149.981 153.404 97.669  1.00 59.72  ? 205 TYR A C   1 
ATOM   1632  O O   . TYR A 1 259 ? 150.449 153.934 98.682  1.00 65.23  ? 205 TYR A O   1 
ATOM   1633  C CB  . TYR A 1 259 ? 150.385 150.948 97.596  1.00 57.82  ? 205 TYR A CB  1 
ATOM   1634  C CG  . TYR A 1 259 ? 150.882 149.733 96.846  1.00 61.61  ? 205 TYR A CG  1 
ATOM   1635  C CD1 . TYR A 1 259 ? 152.213 149.348 96.908  1.00 68.60  ? 205 TYR A CD1 1 
ATOM   1636  C CD2 . TYR A 1 259 ? 150.013 148.958 96.091  1.00 58.77  ? 205 TYR A CD2 1 
ATOM   1637  C CE1 . TYR A 1 259 ? 152.666 148.235 96.228  1.00 69.09  ? 205 TYR A CE1 1 
ATOM   1638  C CE2 . TYR A 1 259 ? 150.458 147.844 95.410  1.00 60.08  ? 205 TYR A CE2 1 
ATOM   1639  C CZ  . TYR A 1 259 ? 151.785 147.487 95.481  1.00 65.71  ? 205 TYR A CZ  1 
ATOM   1640  O OH  . TYR A 1 259 ? 152.233 146.377 94.804  1.00 71.55  ? 205 TYR A OH  1 
ATOM   1641  N N   . PRO A 1 260 ? 148.802 153.771 97.171  1.00 55.41  ? 206 PRO A N   1 
ATOM   1642  C CA  . PRO A 1 260 ? 147.988 154.778 97.858  1.00 52.68  ? 206 PRO A CA  1 
ATOM   1643  C C   . PRO A 1 260 ? 147.393 154.225 99.143  1.00 51.83  ? 206 PRO A C   1 
ATOM   1644  O O   . PRO A 1 260 ? 147.319 153.014 99.357  1.00 58.57  ? 206 PRO A O   1 
ATOM   1645  C CB  . PRO A 1 260 ? 146.894 155.103 96.837  1.00 48.08  ? 206 PRO A CB  1 
ATOM   1646  C CG  . PRO A 1 260 ? 146.774 153.858 96.028  1.00 47.82  ? 206 PRO A CG  1 
ATOM   1647  C CD  . PRO A 1 260 ? 148.168 153.305 95.926  1.00 51.66  ? 206 PRO A CD  1 
ATOM   1648  N N   . ARG A 1 261 ? 146.958 155.138 100.009 1.00 48.86  ? 207 ARG A N   1 
ATOM   1649  C CA  . ARG A 1 261 ? 146.398 154.744 101.294 1.00 50.09  ? 207 ARG A CA  1 
ATOM   1650  C C   . ARG A 1 261 ? 145.455 155.827 101.791 1.00 50.58  ? 207 ARG A C   1 
ATOM   1651  O O   . ARG A 1 261 ? 145.831 157.004 101.838 1.00 56.89  ? 207 ARG A O   1 
ATOM   1652  C CB  . ARG A 1 261 ? 147.508 154.505 102.321 1.00 52.75  ? 207 ARG A CB  1 
ATOM   1653  C CG  . ARG A 1 261 ? 147.004 154.343 103.741 1.00 53.87  ? 207 ARG A CG  1 
ATOM   1654  C CD  . ARG A 1 261 ? 146.500 152.939 103.988 1.00 54.54  ? 207 ARG A CD  1 
ATOM   1655  N NE  . ARG A 1 261 ? 147.596 151.979 103.997 1.00 57.80  ? 207 ARG A NE  1 
ATOM   1656  C CZ  . ARG A 1 261 ? 148.354 151.725 105.054 1.00 62.29  ? 207 ARG A CZ  1 
ATOM   1657  N NH1 . ARG A 1 261 ? 148.161 152.343 106.207 1.00 60.77  ? 207 ARG A NH1 1 
ATOM   1658  N NH2 . ARG A 1 261 ? 149.331 150.828 104.951 1.00 64.22  ? 207 ARG A NH2 1 
ATOM   1659  N N   . LEU A 1 262 ? 144.241 155.424 102.163 1.00 43.32  ? 208 LEU A N   1 
ATOM   1660  C CA  . LEU A 1 262 ? 143.276 156.300 102.815 1.00 43.99  ? 208 LEU A CA  1 
ATOM   1661  C C   . LEU A 1 262 ? 142.927 155.724 104.178 1.00 46.79  ? 208 LEU A C   1 
ATOM   1662  O O   . LEU A 1 262 ? 142.527 154.563 104.280 1.00 49.89  ? 208 LEU A O   1 
ATOM   1663  C CB  . LEU A 1 262 ? 142.008 156.461 101.975 1.00 41.15  ? 208 LEU A CB  1 
ATOM   1664  C CG  . LEU A 1 262 ? 142.156 157.045 100.572 1.00 40.98  ? 208 LEU A CG  1 
ATOM   1665  C CD1 . LEU A 1 262 ? 140.790 157.322 99.972  1.00 42.66  ? 208 LEU A CD1 1 
ATOM   1666  C CD2 . LEU A 1 262 ? 142.994 158.309 100.596 1.00 44.57  ? 208 LEU A CD2 1 
ATOM   1667  N N   . SER A 1 263 ? 143.057 156.533 105.218 1.00 45.26  ? 209 SER A N   1 
ATOM   1668  C CA  . SER A 1 263 ? 142.822 156.087 106.581 1.00 44.83  ? 209 SER A CA  1 
ATOM   1669  C C   . SER A 1 263 ? 141.661 156.861 107.183 1.00 45.52  ? 209 SER A C   1 
ATOM   1670  O O   . SER A 1 263 ? 141.554 158.077 107.004 1.00 53.36  ? 209 SER A O   1 
ATOM   1671  C CB  . SER A 1 263 ? 144.074 156.265 107.438 1.00 49.70  ? 209 SER A CB  1 
ATOM   1672  O OG  . SER A 1 263 ? 145.188 155.634 106.834 1.00 52.48  ? 209 SER A OG  1 
ATOM   1673  N N   . LEU A 1 264 ? 140.800 156.147 107.901 1.00 44.44  ? 210 LEU A N   1 
ATOM   1674  C CA  . LEU A 1 264 ? 139.651 156.734 108.582 1.00 47.74  ? 210 LEU A CA  1 
ATOM   1675  C C   . LEU A 1 264 ? 139.724 156.312 110.042 1.00 58.24  ? 210 LEU A C   1 
ATOM   1676  O O   . LEU A 1 264 ? 139.575 155.128 110.353 1.00 62.25  ? 210 LEU A O   1 
ATOM   1677  C CB  . LEU A 1 264 ? 138.343 156.280 107.934 1.00 44.94  ? 210 LEU A CB  1 
ATOM   1678  C CG  . LEU A 1 264 ? 137.050 156.421 108.732 1.00 49.41  ? 210 LEU A CG  1 
ATOM   1679  C CD1 . LEU A 1 264 ? 136.792 157.867 109.107 1.00 53.45  ? 210 LEU A CD1 1 
ATOM   1680  C CD2 . LEU A 1 264 ? 135.883 155.856 107.940 1.00 49.14  ? 210 LEU A CD2 1 
ATOM   1681  N N   . SER A 1 265 ? 139.952 157.270 110.935 1.00 55.18  ? 211 SER A N   1 
ATOM   1682  C CA  . SER A 1 265 ? 140.269 156.975 112.327 1.00 54.73  ? 211 SER A CA  1 
ATOM   1683  C C   . SER A 1 265 ? 139.206 157.562 113.240 1.00 57.88  ? 211 SER A C   1 
ATOM   1684  O O   . SER A 1 265 ? 138.815 158.719 113.071 1.00 67.30  ? 211 SER A O   1 
ATOM   1685  C CB  . SER A 1 265 ? 141.642 157.535 112.697 1.00 60.14  ? 211 SER A CB  1 
ATOM   1686  O OG  . SER A 1 265 ? 142.590 157.271 111.679 1.00 65.43  ? 211 SER A OG  1 
ATOM   1687  N N   . PHE A 1 266 ? 138.742 156.768 114.204 1.00 59.56  ? 212 PHE A N   1 
ATOM   1688  C CA  . PHE A 1 266 ? 137.809 157.226 115.224 1.00 58.94  ? 212 PHE A CA  1 
ATOM   1689  C C   . PHE A 1 266 ? 138.471 157.116 116.585 1.00 63.08  ? 212 PHE A C   1 
ATOM   1690  O O   . PHE A 1 266 ? 139.029 156.066 116.924 1.00 70.60  ? 212 PHE A O   1 
ATOM   1691  C CB  . PHE A 1 266 ? 136.519 156.404 115.231 1.00 62.73  ? 212 PHE A CB  1 
ATOM   1692  C CG  . PHE A 1 266 ? 136.053 155.987 113.875 1.00 65.13  ? 212 PHE A CG  1 
ATOM   1693  C CD1 . PHE A 1 266 ? 135.286 156.837 113.102 1.00 64.92  ? 212 PHE A CD1 1 
ATOM   1694  C CD2 . PHE A 1 266 ? 136.368 154.734 113.381 1.00 65.11  ? 212 PHE A CD2 1 
ATOM   1695  C CE1 . PHE A 1 266 ? 134.853 156.449 111.856 1.00 70.71  ? 212 PHE A CE1 1 
ATOM   1696  C CE2 . PHE A 1 266 ? 135.937 154.342 112.137 1.00 67.62  ? 212 PHE A CE2 1 
ATOM   1697  C CZ  . PHE A 1 266 ? 135.177 155.199 111.374 1.00 70.57  ? 212 PHE A CZ  1 
ATOM   1698  N N   . ARG A 1 267 ? 138.393 158.185 117.369 1.00 62.12  ? 213 ARG A N   1 
ATOM   1699  C CA  . ARG A 1 267 ? 138.861 158.175 118.749 1.00 67.00  ? 213 ARG A CA  1 
ATOM   1700  C C   . ARG A 1 267 ? 137.652 157.985 119.657 1.00 64.91  ? 213 ARG A C   1 
ATOM   1701  O O   . ARG A 1 267 ? 136.861 158.912 119.854 1.00 66.13  ? 213 ARG A O   1 
ATOM   1702  C CB  . ARG A 1 267 ? 139.616 159.457 119.085 1.00 67.99  ? 213 ARG A CB  1 
ATOM   1703  C CG  . ARG A 1 267 ? 140.114 159.498 120.514 1.00 69.70  ? 213 ARG A CG  1 
ATOM   1704  C CD  . ARG A 1 267 ? 141.315 160.413 120.671 1.00 74.31  ? 213 ARG A CD  1 
ATOM   1705  N NE  . ARG A 1 267 ? 141.008 161.800 120.342 1.00 80.44  ? 213 ARG A NE  1 
ATOM   1706  C CZ  . ARG A 1 267 ? 141.355 162.395 119.210 1.00 86.64  ? 213 ARG A CZ  1 
ATOM   1707  N NH1 . ARG A 1 267 ? 142.021 161.750 118.266 1.00 84.92  ? 213 ARG A NH1 1 
ATOM   1708  N NH2 . ARG A 1 267 ? 141.031 163.671 119.022 1.00 89.52  ? 213 ARG A NH2 1 
ATOM   1709  N N   . LEU A 1 268 ? 137.513 156.783 120.202 1.00 65.02  ? 214 LEU A N   1 
ATOM   1710  C CA  . LEU A 1 268 ? 136.389 156.415 121.048 1.00 64.57  ? 214 LEU A CA  1 
ATOM   1711  C C   . LEU A 1 268 ? 136.767 156.568 122.514 1.00 70.28  ? 214 LEU A C   1 
ATOM   1712  O O   . LEU A 1 268 ? 137.895 156.261 122.909 1.00 74.71  ? 214 LEU A O   1 
ATOM   1713  C CB  . LEU A 1 268 ? 135.957 154.972 120.782 1.00 64.98  ? 214 LEU A CB  1 
ATOM   1714  C CG  . LEU A 1 268 ? 135.661 154.552 119.344 1.00 63.19  ? 214 LEU A CG  1 
ATOM   1715  C CD1 . LEU A 1 268 ? 135.498 153.045 119.267 1.00 57.68  ? 214 LEU A CD1 1 
ATOM   1716  C CD2 . LEU A 1 268 ? 134.414 155.244 118.838 1.00 62.84  ? 214 LEU A CD2 1 
ATOM   1717  N N   . LYS A 1 269 ? 135.823 157.045 123.318 1.00 69.67  ? 215 LYS A N   1 
ATOM   1718  C CA  . LYS A 1 269 ? 135.989 157.114 124.763 1.00 68.33  ? 215 LYS A CA  1 
ATOM   1719  C C   . LYS A 1 269 ? 134.975 156.192 125.419 1.00 68.21  ? 215 LYS A C   1 
ATOM   1720  O O   . LYS A 1 269 ? 133.793 156.204 125.060 1.00 70.29  ? 215 LYS A O   1 
ATOM   1721  C CB  . LYS A 1 269 ? 135.822 158.540 125.287 1.00 65.55  ? 215 LYS A CB  1 
ATOM   1722  C CG  . LYS A 1 269 ? 136.140 158.672 126.767 1.00 72.42  ? 215 LYS A CG  1 
ATOM   1723  C CD  . LYS A 1 269 ? 135.836 160.061 127.294 1.00 80.65  ? 215 LYS A CD  1 
ATOM   1724  C CE  . LYS A 1 269 ? 136.124 160.148 128.784 1.00 86.13  ? 215 LYS A CE  1 
ATOM   1725  N NZ  . LYS A 1 269 ? 135.744 161.470 129.351 1.00 92.36  ? 215 LYS A NZ  1 
ATOM   1726  N N   . ARG A 1 270 ? 135.437 155.401 126.382 1.00 65.38  ? 216 ARG A N   1 
ATOM   1727  C CA  . ARG A 1 270 ? 134.575 154.443 127.056 1.00 64.11  ? 216 ARG A CA  1 
ATOM   1728  C C   . ARG A 1 270 ? 133.788 155.120 128.169 1.00 66.59  ? 216 ARG A C   1 
ATOM   1729  O O   . ARG A 1 270 ? 134.320 155.953 128.908 1.00 67.43  ? 216 ARG A O   1 
ATOM   1730  C CB  . ARG A 1 270 ? 135.405 153.296 127.627 1.00 57.21  ? 216 ARG A CB  1 
ATOM   1731  C CG  . ARG A 1 270 ? 134.593 152.086 128.029 1.00 56.74  ? 216 ARG A CG  1 
ATOM   1732  C CD  . ARG A 1 270 ? 135.490 151.031 128.632 1.00 52.88  ? 216 ARG A CD  1 
ATOM   1733  N NE  . ARG A 1 270 ? 136.618 150.728 127.762 1.00 46.48  ? 216 ARG A NE  1 
ATOM   1734  C CZ  . ARG A 1 270 ? 136.631 149.744 126.875 1.00 49.47  ? 216 ARG A CZ  1 
ATOM   1735  N NH1 . ARG A 1 270 ? 135.590 148.944 126.715 1.00 52.14  ? 216 ARG A NH1 1 
ATOM   1736  N NH2 . ARG A 1 270 ? 137.719 149.554 126.134 1.00 57.25  ? 216 ARG A NH2 1 
ATOM   1737  N N   . ASN A 1 271 ? 132.513 154.759 128.282 1.00 64.94  ? 217 ASN A N   1 
ATOM   1738  C CA  . ASN A 1 271 ? 131.685 155.294 129.348 1.00 61.26  ? 217 ASN A CA  1 
ATOM   1739  C C   . ASN A 1 271 ? 132.114 154.714 130.694 1.00 65.08  ? 217 ASN A C   1 
ATOM   1740  O O   . ASN A 1 271 ? 132.973 153.833 130.783 1.00 67.78  ? 217 ASN A O   1 
ATOM   1741  C CB  . ASN A 1 271 ? 130.210 154.998 129.082 1.00 61.06  ? 217 ASN A CB  1 
ATOM   1742  C CG  . ASN A 1 271 ? 129.701 155.669 127.825 1.00 64.79  ? 217 ASN A CG  1 
ATOM   1743  O OD1 . ASN A 1 271 ? 130.268 156.658 127.362 1.00 68.53  ? 217 ASN A OD1 1 
ATOM   1744  N ND2 . ASN A 1 271 ? 128.623 155.135 127.266 1.00 66.02  ? 217 ASN A ND2 1 
ATOM   1745  N N   . ILE A 1 272 ? 131.496 155.222 131.756 1.00 63.15  ? 218 ILE A N   1 
ATOM   1746  C CA  . ILE A 1 272 ? 131.855 154.837 133.115 1.00 59.57  ? 218 ILE A CA  1 
ATOM   1747  C C   . ILE A 1 272 ? 130.652 154.427 133.950 1.00 61.38  ? 218 ILE A C   1 
ATOM   1748  O O   . ILE A 1 272 ? 130.838 153.836 135.025 1.00 63.92  ? 218 ILE A O   1 
ATOM   1749  C CB  . ILE A 1 272 ? 132.632 155.967 133.826 1.00 58.12  ? 218 ILE A CB  1 
ATOM   1750  C CG1 . ILE A 1 272 ? 133.475 155.414 134.975 1.00 60.14  ? 218 ILE A CG1 1 
ATOM   1751  C CG2 . ILE A 1 272 ? 131.676 157.036 134.324 1.00 65.16  ? 218 ILE A CG2 1 
ATOM   1752  C CD1 . ILE A 1 272 ? 134.435 154.329 134.555 1.00 61.31  ? 218 ILE A CD1 1 
ATOM   1753  N N   . GLY A 1 273 ? 129.428 154.700 133.494 1.00 59.11  ? 219 GLY A N   1 
ATOM   1754  C CA  . GLY A 1 273 ? 128.262 154.418 134.314 1.00 56.94  ? 219 GLY A CA  1 
ATOM   1755  C C   . GLY A 1 273 ? 128.096 152.944 134.631 1.00 58.20  ? 219 GLY A C   1 
ATOM   1756  O O   . GLY A 1 273 ? 127.767 152.576 135.762 1.00 63.28  ? 219 GLY A O   1 
ATOM   1757  N N   . TYR A 1 274 ? 128.317 152.080 133.639 1.00 56.17  ? 220 TYR A N   1 
ATOM   1758  C CA  . TYR A 1 274 ? 128.147 150.648 133.857 1.00 58.99  ? 220 TYR A CA  1 
ATOM   1759  C C   . TYR A 1 274 ? 129.126 150.130 134.902 1.00 60.86  ? 220 TYR A C   1 
ATOM   1760  O O   . TYR A 1 274 ? 128.758 149.342 135.779 1.00 62.73  ? 220 TYR A O   1 
ATOM   1761  C CB  . TYR A 1 274 ? 128.316 149.891 132.541 1.00 60.41  ? 220 TYR A CB  1 
ATOM   1762  C CG  . TYR A 1 274 ? 128.336 148.390 132.709 1.00 65.25  ? 220 TYR A CG  1 
ATOM   1763  C CD1 . TYR A 1 274 ? 127.161 147.679 132.909 1.00 68.55  ? 220 TYR A CD1 1 
ATOM   1764  C CD2 . TYR A 1 274 ? 129.529 147.685 132.669 1.00 61.60  ? 220 TYR A CD2 1 
ATOM   1765  C CE1 . TYR A 1 274 ? 127.175 146.310 133.063 1.00 68.43  ? 220 TYR A CE1 1 
ATOM   1766  C CE2 . TYR A 1 274 ? 129.552 146.315 132.820 1.00 65.05  ? 220 TYR A CE2 1 
ATOM   1767  C CZ  . TYR A 1 274 ? 128.372 145.633 133.018 1.00 69.19  ? 220 TYR A CZ  1 
ATOM   1768  O OH  . TYR A 1 274 ? 128.391 144.268 133.170 1.00 74.61  ? 220 TYR A OH  1 
ATOM   1769  N N   . PHE A 1 275 ? 130.386 150.559 134.819 1.00 59.22  ? 221 PHE A N   1 
ATOM   1770  C CA  . PHE A 1 275 ? 131.385 150.087 135.770 1.00 54.61  ? 221 PHE A CA  1 
ATOM   1771  C C   . PHE A 1 275 ? 131.155 150.668 137.157 1.00 55.83  ? 221 PHE A C   1 
ATOM   1772  O O   . PHE A 1 275 ? 131.480 150.020 138.159 1.00 60.11  ? 221 PHE A O   1 
ATOM   1773  C CB  . PHE A 1 275 ? 132.782 150.423 135.263 1.00 51.06  ? 221 PHE A CB  1 
ATOM   1774  C CG  . PHE A 1 275 ? 133.101 149.794 133.942 1.00 53.50  ? 221 PHE A CG  1 
ATOM   1775  C CD1 . PHE A 1 275 ? 132.793 150.442 132.758 1.00 55.78  ? 221 PHE A CD1 1 
ATOM   1776  C CD2 . PHE A 1 275 ? 133.692 148.545 133.883 1.00 54.17  ? 221 PHE A CD2 1 
ATOM   1777  C CE1 . PHE A 1 275 ? 133.078 149.860 131.542 1.00 56.12  ? 221 PHE A CE1 1 
ATOM   1778  C CE2 . PHE A 1 275 ? 133.980 147.959 132.670 1.00 54.93  ? 221 PHE A CE2 1 
ATOM   1779  C CZ  . PHE A 1 275 ? 133.673 148.617 131.498 1.00 56.31  ? 221 PHE A CZ  1 
ATOM   1780  N N   . ILE A 1 276 ? 130.608 151.881 137.239 1.00 55.05  ? 222 ILE A N   1 
ATOM   1781  C CA  . ILE A 1 276 ? 130.214 152.429 138.533 1.00 53.78  ? 222 ILE A CA  1 
ATOM   1782  C C   . ILE A 1 276 ? 129.106 151.581 139.145 1.00 54.61  ? 222 ILE A C   1 
ATOM   1783  O O   . ILE A 1 276 ? 129.152 151.224 140.327 1.00 55.56  ? 222 ILE A O   1 
ATOM   1784  C CB  . ILE A 1 276 ? 129.787 153.900 138.385 1.00 50.32  ? 222 ILE A CB  1 
ATOM   1785  C CG1 . ILE A 1 276 ? 130.997 154.776 138.060 1.00 51.49  ? 222 ILE A CG1 1 
ATOM   1786  C CG2 . ILE A 1 276 ? 129.098 154.386 139.645 1.00 50.26  ? 222 ILE A CG2 1 
ATOM   1787  C CD1 . ILE A 1 276 ? 132.059 154.763 139.129 1.00 50.56  ? 222 ILE A CD1 1 
ATOM   1788  N N   . LEU A 1 277 ? 128.102 151.229 138.341 1.00 56.79  ? 223 LEU A N   1 
ATOM   1789  C CA  . LEU A 1 277 ? 126.994 150.422 138.840 1.00 54.19  ? 223 LEU A CA  1 
ATOM   1790  C C   . LEU A 1 277 ? 127.390 148.976 139.108 1.00 57.64  ? 223 LEU A C   1 
ATOM   1791  O O   . LEU A 1 277 ? 126.685 148.283 139.848 1.00 64.35  ? 223 LEU A O   1 
ATOM   1792  C CB  . LEU A 1 277 ? 125.835 150.446 137.845 1.00 57.43  ? 223 LEU A CB  1 
ATOM   1793  C CG  . LEU A 1 277 ? 125.046 151.745 137.713 1.00 58.73  ? 223 LEU A CG  1 
ATOM   1794  C CD1 . LEU A 1 277 ? 124.121 151.669 136.513 1.00 63.61  ? 223 LEU A CD1 1 
ATOM   1795  C CD2 . LEU A 1 277 ? 124.256 152.003 138.980 1.00 53.45  ? 223 LEU A CD2 1 
ATOM   1796  N N   . GLN A 1 278 ? 128.485 148.507 138.525 1.00 57.48  ? 224 GLN A N   1 
ATOM   1797  C CA  . GLN A 1 278 ? 128.828 147.091 138.547 1.00 59.19  ? 224 GLN A CA  1 
ATOM   1798  C C   . GLN A 1 278 ? 130.023 146.757 139.423 1.00 59.99  ? 224 GLN A C   1 
ATOM   1799  O O   . GLN A 1 278 ? 130.000 145.738 140.118 1.00 63.21  ? 224 GLN A O   1 
ATOM   1800  C CB  . GLN A 1 278 ? 129.095 146.605 137.116 1.00 60.52  ? 224 GLN A CB  1 
ATOM   1801  C CG  . GLN A 1 278 ? 129.640 145.191 137.014 1.00 72.02  ? 224 GLN A CG  1 
ATOM   1802  C CD  . GLN A 1 278 ? 128.573 144.131 137.203 1.00 84.99  ? 224 GLN A CD  1 
ATOM   1803  O OE1 . GLN A 1 278 ? 127.906 144.077 138.236 1.00 88.25  ? 224 GLN A OE1 1 
ATOM   1804  N NE2 . GLN A 1 278 ? 128.406 143.279 136.197 1.00 86.00  ? 224 GLN A NE2 1 
ATOM   1805  N N   . THR A 1 279 ? 131.072 147.575 139.411 1.00 59.04  ? 225 THR A N   1 
ATOM   1806  C CA  . THR A 1 279 ? 132.315 147.223 140.088 1.00 56.20  ? 225 THR A CA  1 
ATOM   1807  C C   . THR A 1 279 ? 132.669 148.163 141.228 1.00 56.83  ? 225 THR A C   1 
ATOM   1808  O O   . THR A 1 279 ? 132.932 147.700 142.344 1.00 62.33  ? 225 THR A O   1 
ATOM   1809  C CB  . THR A 1 279 ? 133.470 147.182 139.076 1.00 54.65  ? 225 THR A CB  1 
ATOM   1810  O OG1 . THR A 1 279 ? 133.797 148.515 138.670 1.00 57.30  ? 225 THR A OG1 1 
ATOM   1811  C CG2 . THR A 1 279 ? 133.078 146.374 137.852 1.00 59.49  ? 225 THR A CG2 1 
ATOM   1812  N N   . TYR A 1 280 ? 132.687 149.475 140.986 1.00 54.06  ? 226 TYR A N   1 
ATOM   1813  C CA  . TYR A 1 280 ? 133.210 150.401 141.988 1.00 53.15  ? 226 TYR A CA  1 
ATOM   1814  C C   . TYR A 1 280 ? 132.290 150.498 143.199 1.00 55.55  ? 226 TYR A C   1 
ATOM   1815  O O   . TYR A 1 280 ? 132.752 150.438 144.346 1.00 56.68  ? 226 TYR A O   1 
ATOM   1816  C CB  . TYR A 1 280 ? 133.430 151.776 141.364 1.00 52.50  ? 226 TYR A CB  1 
ATOM   1817  C CG  . TYR A 1 280 ? 134.556 151.801 140.364 1.00 55.44  ? 226 TYR A CG  1 
ATOM   1818  C CD1 . TYR A 1 280 ? 135.867 151.982 140.774 1.00 54.33  ? 226 TYR A CD1 1 
ATOM   1819  C CD2 . TYR A 1 280 ? 134.311 151.634 139.011 1.00 57.12  ? 226 TYR A CD2 1 
ATOM   1820  C CE1 . TYR A 1 280 ? 136.900 152.001 139.866 1.00 54.76  ? 226 TYR A CE1 1 
ATOM   1821  C CE2 . TYR A 1 280 ? 135.338 151.652 138.095 1.00 56.61  ? 226 TYR A CE2 1 
ATOM   1822  C CZ  . TYR A 1 280 ? 136.630 151.836 138.528 1.00 57.55  ? 226 TYR A CZ  1 
ATOM   1823  O OH  . TYR A 1 280 ? 137.661 151.856 137.621 1.00 61.08  ? 226 TYR A OH  1 
ATOM   1824  N N   . MET A 1 281 ? 130.989 150.667 142.967 1.00 52.90  ? 227 MET A N   1 
ATOM   1825  C CA  . MET A 1 281 ? 130.057 150.756 144.089 1.00 54.02  ? 227 MET A CA  1 
ATOM   1826  C C   . MET A 1 281 ? 130.046 149.494 144.940 1.00 59.76  ? 227 MET A C   1 
ATOM   1827  O O   . MET A 1 281 ? 130.068 149.615 146.178 1.00 66.01  ? 227 MET A O   1 
ATOM   1828  C CB  . MET A 1 281 ? 128.653 151.105 143.585 1.00 51.97  ? 227 MET A CB  1 
ATOM   1829  C CG  . MET A 1 281 ? 128.502 152.535 143.097 1.00 67.08  ? 227 MET A CG  1 
ATOM   1830  S SD  . MET A 1 281 ? 128.939 153.764 144.340 1.00 96.69  ? 227 MET A SD  1 
ATOM   1831  C CE  . MET A 1 281 ? 127.770 153.365 145.637 1.00 76.47  ? 227 MET A CE  1 
ATOM   1832  N N   . PRO A 1 282 ? 129.986 148.278 144.380 1.00 55.48  ? 228 PRO A N   1 
ATOM   1833  C CA  . PRO A 1 282 ? 130.083 147.095 145.248 1.00 53.42  ? 228 PRO A CA  1 
ATOM   1834  C C   . PRO A 1 282 ? 131.358 147.054 146.069 1.00 53.38  ? 228 PRO A C   1 
ATOM   1835  O O   . PRO A 1 282 ? 131.311 146.681 147.244 1.00 56.30  ? 228 PRO A O   1 
ATOM   1836  C CB  . PRO A 1 282 ? 130.003 145.930 144.254 1.00 54.59  ? 228 PRO A CB  1 
ATOM   1837  C CG  . PRO A 1 282 ? 129.233 146.472 143.122 1.00 54.46  ? 228 PRO A CG  1 
ATOM   1838  C CD  . PRO A 1 282 ? 129.677 147.895 142.990 1.00 55.09  ? 228 PRO A CD  1 
ATOM   1839  N N   . SER A 1 283 ? 132.495 147.451 145.496 1.00 52.07  ? 229 SER A N   1 
ATOM   1840  C CA  . SER A 1 283 ? 133.743 147.427 146.252 1.00 53.39  ? 229 SER A CA  1 
ATOM   1841  C C   . SER A 1 283 ? 133.718 148.433 147.396 1.00 57.11  ? 229 SER A C   1 
ATOM   1842  O O   . SER A 1 283 ? 134.132 148.117 148.520 1.00 64.26  ? 229 SER A O   1 
ATOM   1843  C CB  . SER A 1 283 ? 134.923 147.693 145.322 1.00 55.55  ? 229 SER A CB  1 
ATOM   1844  O OG  . SER A 1 283 ? 134.994 146.711 144.306 1.00 61.01  ? 229 SER A OG  1 
ATOM   1845  N N   . ILE A 1 284 ? 133.225 149.645 147.134 1.00 55.86  ? 230 ILE A N   1 
ATOM   1846  C CA  . ILE A 1 284 ? 133.139 150.649 148.189 1.00 57.32  ? 230 ILE A CA  1 
ATOM   1847  C C   . ILE A 1 284 ? 132.206 150.179 149.298 1.00 60.02  ? 230 ILE A C   1 
ATOM   1848  O O   . ILE A 1 284 ? 132.509 150.323 150.490 1.00 63.76  ? 230 ILE A O   1 
ATOM   1849  C CB  . ILE A 1 284 ? 132.689 152.001 147.607 1.00 56.50  ? 230 ILE A CB  1 
ATOM   1850  C CG1 . ILE A 1 284 ? 133.703 152.501 146.581 1.00 55.88  ? 230 ILE A CG1 1 
ATOM   1851  C CG2 . ILE A 1 284 ? 132.511 153.022 148.715 1.00 57.23  ? 230 ILE A CG2 1 
ATOM   1852  C CD1 . ILE A 1 284 ? 133.283 153.768 145.870 1.00 54.08  ? 230 ILE A CD1 1 
ATOM   1853  N N   . LEU A 1 285 ? 131.060 149.606 148.926 1.00 55.74  ? 231 LEU A N   1 
ATOM   1854  C CA  . LEU A 1 285 ? 130.100 149.159 149.929 1.00 57.11  ? 231 LEU A CA  1 
ATOM   1855  C C   . LEU A 1 285 ? 130.644 147.991 150.741 1.00 59.05  ? 231 LEU A C   1 
ATOM   1856  O O   . LEU A 1 285 ? 130.411 147.913 151.951 1.00 60.90  ? 231 LEU A O   1 
ATOM   1857  C CB  . LEU A 1 285 ? 128.780 148.794 149.257 1.00 52.49  ? 231 LEU A CB  1 
ATOM   1858  C CG  . LEU A 1 285 ? 128.137 149.991 148.554 1.00 60.87  ? 231 LEU A CG  1 
ATOM   1859  C CD1 . LEU A 1 285 ? 127.042 149.553 147.592 1.00 67.51  ? 231 LEU A CD1 1 
ATOM   1860  C CD2 . LEU A 1 285 ? 127.610 150.996 149.567 1.00 62.90  ? 231 LEU A CD2 1 
ATOM   1861  N N   . ILE A 1 286 ? 131.380 147.077 150.104 1.00 56.68  ? 232 ILE A N   1 
ATOM   1862  C CA  . ILE A 1 286 ? 131.977 145.976 150.852 1.00 53.32  ? 232 ILE A CA  1 
ATOM   1863  C C   . ILE A 1 286 ? 133.033 146.499 151.817 1.00 57.69  ? 232 ILE A C   1 
ATOM   1864  O O   . ILE A 1 286 ? 133.129 146.035 152.959 1.00 65.68  ? 232 ILE A O   1 
ATOM   1865  C CB  . ILE A 1 286 ? 132.554 144.915 149.897 1.00 52.40  ? 232 ILE A CB  1 
ATOM   1866  C CG1 . ILE A 1 286 ? 131.436 144.273 149.078 1.00 55.22  ? 232 ILE A CG1 1 
ATOM   1867  C CG2 . ILE A 1 286 ? 133.285 143.842 150.676 1.00 54.44  ? 232 ILE A CG2 1 
ATOM   1868  C CD1 . ILE A 1 286 ? 130.261 143.827 149.902 1.00 58.69  ? 232 ILE A CD1 1 
ATOM   1869  N N   . THR A 1 287 ? 133.839 147.472 151.385 1.00 56.03  ? 233 THR A N   1 
ATOM   1870  C CA  . THR A 1 287 ? 134.839 148.037 152.289 1.00 60.15  ? 233 THR A CA  1 
ATOM   1871  C C   . THR A 1 287 ? 134.182 148.730 153.481 1.00 64.99  ? 233 THR A C   1 
ATOM   1872  O O   . THR A 1 287 ? 134.641 148.593 154.622 1.00 65.44  ? 233 THR A O   1 
ATOM   1873  C CB  . THR A 1 287 ? 135.747 149.005 151.533 1.00 61.21  ? 233 THR A CB  1 
ATOM   1874  O OG1 . THR A 1 287 ? 136.326 148.336 150.408 1.00 60.20  ? 233 THR A OG1 1 
ATOM   1875  C CG2 . THR A 1 287 ? 136.862 149.497 152.435 1.00 62.86  ? 233 THR A CG2 1 
ATOM   1876  N N   . ILE A 1 288 ? 133.098 149.470 153.240 1.00 62.82  ? 234 ILE A N   1 
ATOM   1877  C CA  . ILE A 1 288 ? 132.395 150.124 154.343 1.00 62.32  ? 234 ILE A CA  1 
ATOM   1878  C C   . ILE A 1 288 ? 131.774 149.088 155.276 1.00 66.49  ? 234 ILE A C   1 
ATOM   1879  O O   . ILE A 1 288 ? 131.802 149.239 156.505 1.00 71.25  ? 234 ILE A O   1 
ATOM   1880  C CB  . ILE A 1 288 ? 131.346 151.110 153.800 1.00 65.13  ? 234 ILE A CB  1 
ATOM   1881  C CG1 . ILE A 1 288 ? 132.033 152.233 153.023 1.00 68.57  ? 234 ILE A CG1 1 
ATOM   1882  C CG2 . ILE A 1 288 ? 130.514 151.684 154.933 1.00 70.04  ? 234 ILE A CG2 1 
ATOM   1883  C CD1 . ILE A 1 288 ? 131.086 153.288 152.500 1.00 68.86  ? 234 ILE A CD1 1 
ATOM   1884  N N   . LEU A 1 289 ? 131.200 148.024 154.711 1.00 64.55  ? 235 LEU A N   1 
ATOM   1885  C CA  . LEU A 1 289 ? 130.663 146.941 155.527 1.00 65.41  ? 235 LEU A CA  1 
ATOM   1886  C C   . LEU A 1 289 ? 131.750 146.311 156.389 1.00 66.60  ? 235 LEU A C   1 
ATOM   1887  O O   . LEU A 1 289 ? 131.504 145.940 157.542 1.00 68.70  ? 235 LEU A O   1 
ATOM   1888  C CB  . LEU A 1 289 ? 130.010 145.895 154.625 1.00 61.96  ? 235 LEU A CB  1 
ATOM   1889  C CG  . LEU A 1 289 ? 129.552 144.579 155.249 1.00 62.82  ? 235 LEU A CG  1 
ATOM   1890  C CD1 . LEU A 1 289 ? 128.542 144.838 156.346 1.00 69.61  ? 235 LEU A CD1 1 
ATOM   1891  C CD2 . LEU A 1 289 ? 128.964 143.670 154.183 1.00 61.12  ? 235 LEU A CD2 1 
ATOM   1892  N N   . SER A 1 290 ? 132.958 146.174 155.841 1.00 61.38  ? 236 SER A N   1 
ATOM   1893  C CA  . SER A 1 290 ? 134.077 145.683 156.636 1.00 59.11  ? 236 SER A CA  1 
ATOM   1894  C C   . SER A 1 290 ? 134.415 146.654 157.758 1.00 64.29  ? 236 SER A C   1 
ATOM   1895  O O   . SER A 1 290 ? 134.736 146.233 158.876 1.00 69.33  ? 236 SER A O   1 
ATOM   1896  C CB  . SER A 1 290 ? 135.295 145.448 155.747 1.00 61.88  ? 236 SER A CB  1 
ATOM   1897  O OG  . SER A 1 290 ? 135.815 146.676 155.270 1.00 67.90  ? 236 SER A OG  1 
ATOM   1898  N N   . TRP A 1 291 ? 134.360 147.958 157.473 1.00 66.89  ? 237 TRP A N   1 
ATOM   1899  C CA  . TRP A 1 291 ? 134.578 148.955 158.520 1.00 67.88  ? 237 TRP A CA  1 
ATOM   1900  C C   . TRP A 1 291 ? 133.566 148.804 159.645 1.00 71.14  ? 237 TRP A C   1 
ATOM   1901  O O   . TRP A 1 291 ? 133.893 149.018 160.818 1.00 73.94  ? 237 TRP A O   1 
ATOM   1902  C CB  . TRP A 1 291 ? 134.484 150.367 157.949 1.00 66.60  ? 237 TRP A CB  1 
ATOM   1903  C CG  . TRP A 1 291 ? 135.470 150.686 156.896 1.00 69.21  ? 237 TRP A CG  1 
ATOM   1904  C CD1 . TRP A 1 291 ? 136.592 149.985 156.576 1.00 67.92  ? 237 TRP A CD1 1 
ATOM   1905  C CD2 . TRP A 1 291 ? 135.423 151.803 156.007 1.00 71.47  ? 237 TRP A CD2 1 
ATOM   1906  N NE1 . TRP A 1 291 ? 137.250 150.599 155.539 1.00 67.62  ? 237 TRP A NE1 1 
ATOM   1907  C CE2 . TRP A 1 291 ? 136.549 151.718 155.172 1.00 70.19  ? 237 TRP A CE2 1 
ATOM   1908  C CE3 . TRP A 1 291 ? 134.534 152.868 155.837 1.00 72.54  ? 237 TRP A CE3 1 
ATOM   1909  C CZ2 . TRP A 1 291 ? 136.811 152.655 154.183 1.00 71.10  ? 237 TRP A CZ2 1 
ATOM   1910  C CZ3 . TRP A 1 291 ? 134.796 153.798 154.854 1.00 73.15  ? 237 TRP A CZ3 1 
ATOM   1911  C CH2 . TRP A 1 291 ? 135.925 153.687 154.040 1.00 72.02  ? 237 TRP A CH2 1 
ATOM   1912  N N   . VAL A 1 292 ? 132.323 148.458 159.297 1.00 71.74  ? 238 VAL A N   1 
ATOM   1913  C CA  . VAL A 1 292 ? 131.242 148.361 160.282 1.00 72.20  ? 238 VAL A CA  1 
ATOM   1914  C C   . VAL A 1 292 ? 131.638 147.490 161.469 1.00 74.05  ? 238 VAL A C   1 
ATOM   1915  O O   . VAL A 1 292 ? 131.162 147.700 162.591 1.00 78.50  ? 238 VAL A O   1 
ATOM   1916  C CB  . VAL A 1 292 ? 129.955 147.845 159.600 1.00 70.60  ? 238 VAL A CB  1 
ATOM   1917  C CG1 . VAL A 1 292 ? 128.852 147.606 160.615 1.00 71.14  ? 238 VAL A CG1 1 
ATOM   1918  C CG2 . VAL A 1 292 ? 129.484 148.832 158.548 1.00 75.14  ? 238 VAL A CG2 1 
ATOM   1919  N N   . SER A 1 293 ? 132.532 146.522 161.254 1.00 72.23  ? 239 SER A N   1 
ATOM   1920  C CA  . SER A 1 293 ? 132.970 145.644 162.335 1.00 73.52  ? 239 SER A CA  1 
ATOM   1921  C C   . SER A 1 293 ? 133.698 146.392 163.445 1.00 83.05  ? 239 SER A C   1 
ATOM   1922  O O   . SER A 1 293 ? 133.773 145.885 164.569 1.00 91.42  ? 239 SER A O   1 
ATOM   1923  C CB  . SER A 1 293 ? 133.886 144.550 161.788 1.00 72.60  ? 239 SER A CB  1 
ATOM   1924  O OG  . SER A 1 293 ? 135.172 145.064 161.489 1.00 73.89  ? 239 SER A OG  1 
ATOM   1925  N N   . PHE A 1 294 ? 134.242 147.577 163.158 1.00 80.59  ? 240 PHE A N   1 
ATOM   1926  C CA  . PHE A 1 294 ? 135.043 148.281 164.153 1.00 83.79  ? 240 PHE A CA  1 
ATOM   1927  C C   . PHE A 1 294 ? 134.196 148.798 165.309 1.00 88.94  ? 240 PHE A C   1 
ATOM   1928  O O   . PHE A 1 294 ? 134.669 148.834 166.451 1.00 89.31  ? 240 PHE A O   1 
ATOM   1929  C CB  . PHE A 1 294 ? 135.805 149.426 163.492 1.00 81.19  ? 240 PHE A CB  1 
ATOM   1930  C CG  . PHE A 1 294 ? 136.872 148.969 162.543 1.00 77.79  ? 240 PHE A CG  1 
ATOM   1931  C CD1 . PHE A 1 294 ? 137.608 147.829 162.811 1.00 75.88  ? 240 PHE A CD1 1 
ATOM   1932  C CD2 . PHE A 1 294 ? 137.134 149.672 161.381 1.00 79.69  ? 240 PHE A CD2 1 
ATOM   1933  C CE1 . PHE A 1 294 ? 138.588 147.403 161.941 1.00 74.97  ? 240 PHE A CE1 1 
ATOM   1934  C CE2 . PHE A 1 294 ? 138.113 149.249 160.508 1.00 77.26  ? 240 PHE A CE2 1 
ATOM   1935  C CZ  . PHE A 1 294 ? 138.842 148.113 160.789 1.00 74.00  ? 240 PHE A CZ  1 
ATOM   1936  N N   . TRP A 1 295 ? 132.956 149.204 165.043 1.00 89.09  ? 241 TRP A N   1 
ATOM   1937  C CA  . TRP A 1 295 ? 132.064 149.634 166.111 1.00 91.75  ? 241 TRP A CA  1 
ATOM   1938  C C   . TRP A 1 295 ? 131.437 148.465 166.859 1.00 96.47  ? 241 TRP A C   1 
ATOM   1939  O O   . TRP A 1 295 ? 130.751 148.688 167.862 1.00 101.54 ? 241 TRP A O   1 
ATOM   1940  C CB  . TRP A 1 295 ? 130.966 150.541 165.552 1.00 91.53  ? 241 TRP A CB  1 
ATOM   1941  C CG  . TRP A 1 295 ? 131.461 151.900 165.156 1.00 90.86  ? 241 TRP A CG  1 
ATOM   1942  C CD1 . TRP A 1 295 ? 131.653 152.972 165.976 1.00 88.95  ? 241 TRP A CD1 1 
ATOM   1943  C CD2 . TRP A 1 295 ? 131.828 152.331 163.840 1.00 90.24  ? 241 TRP A CD2 1 
ATOM   1944  N NE1 . TRP A 1 295 ? 132.117 154.044 165.254 1.00 85.06  ? 241 TRP A NE1 1 
ATOM   1945  C CE2 . TRP A 1 295 ? 132.233 153.677 163.940 1.00 91.47  ? 241 TRP A CE2 1 
ATOM   1946  C CE3 . TRP A 1 295 ? 131.854 151.710 162.588 1.00 89.56  ? 241 TRP A CE3 1 
ATOM   1947  C CZ2 . TRP A 1 295 ? 132.659 154.412 162.837 1.00 93.75  ? 241 TRP A CZ2 1 
ATOM   1948  C CZ3 . TRP A 1 295 ? 132.276 152.442 161.493 1.00 91.25  ? 241 TRP A CZ3 1 
ATOM   1949  C CH2 . TRP A 1 295 ? 132.672 153.778 161.625 1.00 91.96  ? 241 TRP A CH2 1 
ATOM   1950  N N   . ILE A 1 296 ? 131.650 147.233 166.396 1.00 97.30  ? 242 ILE A N   1 
ATOM   1951  C CA  . ILE A 1 296 ? 131.158 146.065 167.112 1.00 102.19 ? 242 ILE A CA  1 
ATOM   1952  C C   . ILE A 1 296 ? 132.035 145.809 168.333 1.00 105.77 ? 242 ILE A C   1 
ATOM   1953  O O   . ILE A 1 296 ? 133.250 146.052 168.319 1.00 103.39 ? 242 ILE A O   1 
ATOM   1954  C CB  . ILE A 1 296 ? 131.117 144.845 166.172 1.00 101.27 ? 242 ILE A CB  1 
ATOM   1955  C CG1 . ILE A 1 296 ? 130.209 145.133 164.976 1.00 93.14  ? 242 ILE A CG1 1 
ATOM   1956  C CG2 . ILE A 1 296 ? 130.631 143.602 166.901 1.00 103.53 ? 242 ILE A CG2 1 
ATOM   1957  C CD1 . ILE A 1 296 ? 128.773 145.417 165.359 1.00 92.80  ? 242 ILE A CD1 1 
ATOM   1958  N N   . ASN A 1 297 ? 131.411 145.329 169.408 1.00 107.81 ? 243 ASN A N   1 
ATOM   1959  C CA  . ASN A 1 297 ? 132.134 145.065 170.644 1.00 115.82 ? 243 ASN A CA  1 
ATOM   1960  C C   . ASN A 1 297 ? 133.218 144.015 170.421 1.00 120.64 ? 243 ASN A C   1 
ATOM   1961  O O   . ASN A 1 297 ? 133.057 143.075 169.640 1.00 120.44 ? 243 ASN A O   1 
ATOM   1962  C CB  . ASN A 1 297 ? 131.169 144.604 171.736 1.00 120.00 ? 243 ASN A CB  1 
ATOM   1963  C CG  . ASN A 1 297 ? 131.836 144.481 173.091 1.00 129.62 ? 243 ASN A CG  1 
ATOM   1964  O OD1 . ASN A 1 297 ? 132.926 145.009 173.310 1.00 131.00 ? 243 ASN A OD1 1 
ATOM   1965  N ND2 . ASN A 1 297 ? 131.181 143.784 174.012 1.00 132.51 ? 243 ASN A ND2 1 
ATOM   1966  N N   . TYR A 1 298 ? 134.340 144.192 171.124 1.00 124.29 ? 244 TYR A N   1 
ATOM   1967  C CA  . TYR A 1 298 ? 135.501 143.334 170.911 1.00 125.10 ? 244 TYR A CA  1 
ATOM   1968  C C   . TYR A 1 298 ? 135.238 141.892 171.326 1.00 125.49 ? 244 TYR A C   1 
ATOM   1969  O O   . TYR A 1 298 ? 135.872 140.973 170.794 1.00 122.02 ? 244 TYR A O   1 
ATOM   1970  C CB  . TYR A 1 298 ? 136.707 143.891 171.668 1.00 126.65 ? 244 TYR A CB  1 
ATOM   1971  C CG  . TYR A 1 298 ? 136.378 144.402 173.052 1.00 130.38 ? 244 TYR A CG  1 
ATOM   1972  C CD1 . TYR A 1 298 ? 136.164 143.524 174.106 1.00 131.61 ? 244 TYR A CD1 1 
ATOM   1973  C CD2 . TYR A 1 298 ? 136.285 145.764 173.306 1.00 126.83 ? 244 TYR A CD2 1 
ATOM   1974  C CE1 . TYR A 1 298 ? 135.864 143.987 175.374 1.00 134.14 ? 244 TYR A CE1 1 
ATOM   1975  C CE2 . TYR A 1 298 ? 135.986 146.237 174.570 1.00 130.63 ? 244 TYR A CE2 1 
ATOM   1976  C CZ  . TYR A 1 298 ? 135.777 145.344 175.600 1.00 135.65 ? 244 TYR A CZ  1 
ATOM   1977  O OH  . TYR A 1 298 ? 135.479 145.808 176.860 1.00 138.70 ? 244 TYR A OH  1 
ATOM   1978  N N   . ASP A 1 299 ? 134.320 141.669 172.270 1.00 128.03 ? 245 ASP A N   1 
ATOM   1979  C CA  . ASP A 1 299 ? 134.070 140.316 172.756 1.00 131.97 ? 245 ASP A CA  1 
ATOM   1980  C C   . ASP A 1 299 ? 133.446 139.419 171.695 1.00 128.37 ? 245 ASP A C   1 
ATOM   1981  O O   . ASP A 1 299 ? 133.583 138.194 171.779 1.00 124.80 ? 245 ASP A O   1 
ATOM   1982  C CB  . ASP A 1 299 ? 133.173 140.354 173.995 1.00 130.59 ? 245 ASP A CB  1 
ATOM   1983  C CG  . ASP A 1 299 ? 131.730 140.674 173.662 1.00 130.21 ? 245 ASP A CG  1 
ATOM   1984  O OD1 . ASP A 1 299 ? 131.492 141.471 172.730 1.00 128.75 ? 245 ASP A OD1 1 
ATOM   1985  O OD2 . ASP A 1 299 ? 130.831 140.124 174.333 1.00 130.36 ? 245 ASP A OD2 1 
ATOM   1986  N N   . ALA A 1 300 ? 132.763 139.995 170.705 1.00 124.66 ? 246 ALA A N   1 
ATOM   1987  C CA  . ALA A 1 300 ? 132.099 139.218 169.659 1.00 115.66 ? 246 ALA A CA  1 
ATOM   1988  C C   . ALA A 1 300 ? 133.148 138.728 168.666 1.00 109.18 ? 246 ALA A C   1 
ATOM   1989  O O   . ALA A 1 300 ? 133.349 139.290 167.587 1.00 110.68 ? 246 ALA A O   1 
ATOM   1990  C CB  . ALA A 1 300 ? 131.025 140.051 168.971 1.00 109.81 ? 246 ALA A CB  1 
ATOM   1991  N N   . SER A 1 301 ? 133.840 137.654 169.050 1.00 104.51 ? 247 SER A N   1 
ATOM   1992  C CA  . SER A 1 301 ? 134.872 137.091 168.185 1.00 104.29 ? 247 SER A CA  1 
ATOM   1993  C C   . SER A 1 301 ? 134.270 136.510 166.911 1.00 100.54 ? 247 SER A C   1 
ATOM   1994  O O   . SER A 1 301 ? 134.727 136.811 165.799 1.00 97.58  ? 247 SER A O   1 
ATOM   1995  C CB  . SER A 1 301 ? 135.662 136.023 168.942 1.00 105.73 ? 247 SER A CB  1 
ATOM   1996  O OG  . SER A 1 301 ? 134.829 134.943 169.321 1.00 108.54 ? 247 SER A OG  1 
ATOM   1997  N N   . ALA A 1 302 ? 133.234 135.681 167.057 1.00 99.60  ? 248 ALA A N   1 
ATOM   1998  C CA  . ALA A 1 302 ? 132.636 135.026 165.900 1.00 96.79  ? 248 ALA A CA  1 
ATOM   1999  C C   . ALA A 1 302 ? 132.059 136.043 164.926 1.00 92.64  ? 248 ALA A C   1 
ATOM   2000  O O   . ALA A 1 302 ? 132.223 135.907 163.709 1.00 88.53  ? 248 ALA A O   1 
ATOM   2001  C CB  . ALA A 1 302 ? 131.557 134.043 166.352 1.00 93.88  ? 248 ALA A CB  1 
ATOM   2002  N N   . ALA A 1 303 ? 131.382 137.070 165.443 1.00 90.49  ? 249 ALA A N   1 
ATOM   2003  C CA  . ALA A 1 303 ? 130.769 138.068 164.573 1.00 88.50  ? 249 ALA A CA  1 
ATOM   2004  C C   . ALA A 1 303 ? 131.819 138.802 163.748 1.00 83.44  ? 249 ALA A C   1 
ATOM   2005  O O   . ALA A 1 303 ? 131.662 138.974 162.534 1.00 85.30  ? 249 ALA A O   1 
ATOM   2006  C CB  . ALA A 1 303 ? 129.950 139.055 165.404 1.00 91.70  ? 249 ALA A CB  1 
ATOM   2007  N N   . ARG A 1 304 ? 132.909 139.228 164.388 1.00 79.83  ? 250 ARG A N   1 
ATOM   2008  C CA  . ARG A 1 304 ? 133.922 139.994 163.670 1.00 80.35  ? 250 ARG A CA  1 
ATOM   2009  C C   . ARG A 1 304 ? 134.682 139.121 162.679 1.00 83.62  ? 250 ARG A C   1 
ATOM   2010  O O   . ARG A 1 304 ? 135.008 139.569 161.571 1.00 83.26  ? 250 ARG A O   1 
ATOM   2011  C CB  . ARG A 1 304 ? 134.880 140.655 164.658 1.00 81.25  ? 250 ARG A CB  1 
ATOM   2012  C CG  . ARG A 1 304 ? 134.207 141.681 165.554 1.00 90.62  ? 250 ARG A CG  1 
ATOM   2013  C CD  . ARG A 1 304 ? 135.214 142.413 166.419 1.00 96.02  ? 250 ARG A CD  1 
ATOM   2014  N NE  . ARG A 1 304 ? 136.060 143.305 165.637 1.00 92.94  ? 250 ARG A NE  1 
ATOM   2015  C CZ  . ARG A 1 304 ? 137.024 144.058 166.148 1.00 95.62  ? 250 ARG A CZ  1 
ATOM   2016  N NH1 . ARG A 1 304 ? 137.302 144.040 167.441 1.00 103.35 ? 250 ARG A NH1 1 
ATOM   2017  N NH2 . ARG A 1 304 ? 137.729 144.846 165.341 1.00 93.05  ? 250 ARG A NH2 1 
ATOM   2018  N N   . VAL A 1 305 ? 134.959 137.867 163.043 1.00 83.74  ? 251 VAL A N   1 
ATOM   2019  C CA  . VAL A 1 305 ? 135.637 136.985 162.099 1.00 79.47  ? 251 VAL A CA  1 
ATOM   2020  C C   . VAL A 1 305 ? 134.735 136.680 160.910 1.00 75.03  ? 251 VAL A C   1 
ATOM   2021  O O   . VAL A 1 305 ? 135.198 136.621 159.764 1.00 72.79  ? 251 VAL A O   1 
ATOM   2022  C CB  . VAL A 1 305 ? 136.110 135.698 162.794 1.00 80.71  ? 251 VAL A CB  1 
ATOM   2023  C CG1 . VAL A 1 305 ? 136.720 134.757 161.774 1.00 82.57  ? 251 VAL A CG1 1 
ATOM   2024  C CG2 . VAL A 1 305 ? 137.122 136.027 163.861 1.00 82.49  ? 251 VAL A CG2 1 
ATOM   2025  N N   . ALA A 1 306 ? 133.439 136.476 161.158 1.00 72.37  ? 252 ALA A N   1 
ATOM   2026  C CA  . ALA A 1 306 ? 132.506 136.265 160.058 1.00 73.20  ? 252 ALA A CA  1 
ATOM   2027  C C   . ALA A 1 306 ? 132.442 137.489 159.156 1.00 71.46  ? 252 ALA A C   1 
ATOM   2028  O O   . ALA A 1 306 ? 132.423 137.361 157.928 1.00 72.26  ? 252 ALA A O   1 
ATOM   2029  C CB  . ALA A 1 306 ? 131.120 135.923 160.602 1.00 75.75  ? 252 ALA A CB  1 
ATOM   2030  N N   . LEU A 1 307 ? 132.416 138.684 159.751 1.00 69.45  ? 253 LEU A N   1 
ATOM   2031  C CA  . LEU A 1 307 ? 132.462 139.911 158.965 1.00 68.17  ? 253 LEU A CA  1 
ATOM   2032  C C   . LEU A 1 307 ? 133.687 139.933 158.063 1.00 68.74  ? 253 LEU A C   1 
ATOM   2033  O O   . LEU A 1 307 ? 133.578 140.158 156.852 1.00 72.97  ? 253 LEU A O   1 
ATOM   2034  C CB  . LEU A 1 307 ? 132.460 141.126 159.894 1.00 67.79  ? 253 LEU A CB  1 
ATOM   2035  C CG  . LEU A 1 307 ? 131.111 141.622 160.410 1.00 68.71  ? 253 LEU A CG  1 
ATOM   2036  C CD1 . LEU A 1 307 ? 131.224 142.176 161.820 1.00 76.21  ? 253 LEU A CD1 1 
ATOM   2037  C CD2 . LEU A 1 307 ? 130.557 142.675 159.467 1.00 64.93  ? 253 LEU A CD2 1 
ATOM   2038  N N   . GLY A 1 308 ? 134.864 139.679 158.638 1.00 63.98  ? 254 GLY A N   1 
ATOM   2039  C CA  . GLY A 1 308 ? 136.086 139.728 157.848 1.00 64.03  ? 254 GLY A CA  1 
ATOM   2040  C C   . GLY A 1 308 ? 136.103 138.705 156.727 1.00 68.53  ? 254 GLY A C   1 
ATOM   2041  O O   . GLY A 1 308 ? 136.420 139.028 155.577 1.00 70.76  ? 254 GLY A O   1 
ATOM   2042  N N   . ILE A 1 309 ? 135.741 137.460 157.043 1.00 66.74  ? 255 ILE A N   1 
ATOM   2043  C CA  . ILE A 1 309 ? 135.788 136.391 156.049 1.00 59.88  ? 255 ILE A CA  1 
ATOM   2044  C C   . ILE A 1 309 ? 134.790 136.658 154.929 1.00 60.63  ? 255 ILE A C   1 
ATOM   2045  O O   . ILE A 1 309 ? 135.112 136.518 153.742 1.00 63.46  ? 255 ILE A O   1 
ATOM   2046  C CB  . ILE A 1 309 ? 135.531 135.027 156.714 1.00 59.94  ? 255 ILE A CB  1 
ATOM   2047  C CG1 . ILE A 1 309 ? 136.650 134.682 157.694 1.00 61.88  ? 255 ILE A CG1 1 
ATOM   2048  C CG2 . ILE A 1 309 ? 135.399 133.938 155.665 1.00 59.01  ? 255 ILE A CG2 1 
ATOM   2049  C CD1 . ILE A 1 309 ? 136.435 133.364 158.404 1.00 67.58  ? 255 ILE A CD1 1 
ATOM   2050  N N   . THR A 1 310 ? 133.559 137.036 155.289 1.00 59.04  ? 256 THR A N   1 
ATOM   2051  C CA  . THR A 1 310 ? 132.544 137.310 154.281 1.00 59.39  ? 256 THR A CA  1 
ATOM   2052  C C   . THR A 1 310 ? 132.946 138.481 153.398 1.00 62.24  ? 256 THR A C   1 
ATOM   2053  O O   . THR A 1 310 ? 132.778 138.427 152.173 1.00 61.98  ? 256 THR A O   1 
ATOM   2054  C CB  . THR A 1 310 ? 131.197 137.583 154.949 1.00 59.35  ? 256 THR A CB  1 
ATOM   2055  O OG1 . THR A 1 310 ? 131.374 138.525 156.013 1.00 70.20  ? 256 THR A OG1 1 
ATOM   2056  C CG2 . THR A 1 310 ? 130.603 136.298 155.501 1.00 56.55  ? 256 THR A CG2 1 
ATOM   2057  N N   . THR A 1 311 ? 133.481 139.551 153.996 1.00 61.89  ? 257 THR A N   1 
ATOM   2058  C CA  . THR A 1 311 ? 133.910 140.691 153.195 1.00 62.94  ? 257 THR A CA  1 
ATOM   2059  C C   . THR A 1 311 ? 135.019 140.298 152.232 1.00 64.15  ? 257 THR A C   1 
ATOM   2060  O O   . THR A 1 311 ? 134.984 140.671 151.054 1.00 66.41  ? 257 THR A O   1 
ATOM   2061  C CB  . THR A 1 311 ? 134.372 141.837 154.095 1.00 62.76  ? 257 THR A CB  1 
ATOM   2062  O OG1 . THR A 1 311 ? 135.250 141.332 155.107 1.00 67.22  ? 257 THR A OG1 1 
ATOM   2063  C CG2 . THR A 1 311 ? 133.181 142.523 154.745 1.00 66.33  ? 257 THR A CG2 1 
ATOM   2064  N N   . VAL A 1 312 ? 136.003 139.529 152.705 1.00 61.18  ? 258 VAL A N   1 
ATOM   2065  C CA  . VAL A 1 312 ? 137.107 139.131 151.835 1.00 61.19  ? 258 VAL A CA  1 
ATOM   2066  C C   . VAL A 1 312 ? 136.604 138.270 150.682 1.00 64.60  ? 258 VAL A C   1 
ATOM   2067  O O   . VAL A 1 312 ? 136.965 138.490 149.517 1.00 63.92  ? 258 VAL A O   1 
ATOM   2068  C CB  . VAL A 1 312 ? 138.194 138.408 152.651 1.00 57.70  ? 258 VAL A CB  1 
ATOM   2069  C CG1 . VAL A 1 312 ? 139.162 137.696 151.729 1.00 59.10  ? 258 VAL A CG1 1 
ATOM   2070  C CG2 . VAL A 1 312 ? 138.935 139.398 153.528 1.00 57.56  ? 258 VAL A CG2 1 
ATOM   2071  N N   . LEU A 1 313 ? 135.755 137.284 150.982 1.00 60.57  ? 259 LEU A N   1 
ATOM   2072  C CA  . LEU A 1 313 ? 135.284 136.385 149.933 1.00 58.71  ? 259 LEU A CA  1 
ATOM   2073  C C   . LEU A 1 313 ? 134.404 137.113 148.924 1.00 63.95  ? 259 LEU A C   1 
ATOM   2074  O O   . LEU A 1 313 ? 134.511 136.878 147.713 1.00 68.80  ? 259 LEU A O   1 
ATOM   2075  C CB  . LEU A 1 313 ? 134.544 135.199 150.547 1.00 54.34  ? 259 LEU A CB  1 
ATOM   2076  C CG  . LEU A 1 313 ? 135.442 134.233 151.320 1.00 50.81  ? 259 LEU A CG  1 
ATOM   2077  C CD1 . LEU A 1 313 ? 134.673 132.994 151.745 1.00 54.70  ? 259 LEU A CD1 1 
ATOM   2078  C CD2 . LEU A 1 313 ? 136.656 133.854 150.488 1.00 47.51  ? 259 LEU A CD2 1 
ATOM   2079  N N   . THR A 1 314 ? 133.533 138.009 149.392 1.00 58.68  ? 260 THR A N   1 
ATOM   2080  C CA  . THR A 1 314 ? 132.701 138.761 148.461 1.00 61.36  ? 260 THR A CA  1 
ATOM   2081  C C   . THR A 1 314 ? 133.541 139.725 147.631 1.00 64.90  ? 260 THR A C   1 
ATOM   2082  O O   . THR A 1 314 ? 133.254 139.950 146.450 1.00 70.30  ? 260 THR A O   1 
ATOM   2083  C CB  . THR A 1 314 ? 131.605 139.504 149.220 1.00 62.94  ? 260 THR A CB  1 
ATOM   2084  O OG1 . THR A 1 314 ? 130.936 138.589 150.094 1.00 62.92  ? 260 THR A OG1 1 
ATOM   2085  C CG2 . THR A 1 314 ? 130.593 140.089 148.251 1.00 65.88  ? 260 THR A CG2 1 
ATOM   2086  N N   . MET A 1 315 ? 134.596 140.289 148.223 1.00 61.24  ? 261 MET A N   1 
ATOM   2087  C CA  . MET A 1 315 ? 135.512 141.125 147.457 1.00 60.31  ? 261 MET A CA  1 
ATOM   2088  C C   . MET A 1 315 ? 136.184 140.318 146.355 1.00 65.06  ? 261 MET A C   1 
ATOM   2089  O O   . MET A 1 315 ? 136.380 140.810 145.237 1.00 69.23  ? 261 MET A O   1 
ATOM   2090  C CB  . MET A 1 315 ? 136.556 141.742 148.386 1.00 58.70  ? 261 MET A CB  1 
ATOM   2091  C CG  . MET A 1 315 ? 137.492 142.716 147.699 1.00 57.42  ? 261 MET A CG  1 
ATOM   2092  S SD  . MET A 1 315 ? 136.654 144.243 147.245 1.00 67.19  ? 261 MET A SD  1 
ATOM   2093  C CE  . MET A 1 315 ? 136.251 144.886 148.865 1.00 51.36  ? 261 MET A CE  1 
ATOM   2094  N N   . THR A 1 316 ? 136.558 139.074 146.659 1.00 65.97  ? 262 THR A N   1 
ATOM   2095  C CA  . THR A 1 316 ? 137.130 138.209 145.630 1.00 69.03  ? 262 THR A CA  1 
ATOM   2096  C C   . THR A 1 316 ? 136.116 137.907 144.533 1.00 66.74  ? 262 THR A C   1 
ATOM   2097  O O   . THR A 1 316 ? 136.463 137.887 143.346 1.00 65.53  ? 262 THR A O   1 
ATOM   2098  C CB  . THR A 1 316 ? 137.643 136.907 146.246 1.00 63.40  ? 262 THR A CB  1 
ATOM   2099  O OG1 . THR A 1 316 ? 136.574 136.247 146.933 1.00 65.59  ? 262 THR A OG1 1 
ATOM   2100  C CG2 . THR A 1 316 ? 138.775 137.180 147.217 1.00 59.32  ? 262 THR A CG2 1 
ATOM   2101  N N   . THR A 1 317 ? 134.860 137.671 144.907 1.00 65.45  ? 263 THR A N   1 
ATOM   2102  C CA  . THR A 1 317 ? 133.840 137.283 143.936 1.00 67.19  ? 263 THR A CA  1 
ATOM   2103  C C   . THR A 1 317 ? 133.182 138.467 143.234 1.00 69.00  ? 263 THR A C   1 
ATOM   2104  O O   . THR A 1 317 ? 132.307 138.246 142.390 1.00 71.25  ? 263 THR A O   1 
ATOM   2105  C CB  . THR A 1 317 ? 132.753 136.440 144.608 1.00 69.97  ? 263 THR A CB  1 
ATOM   2106  O OG1 . THR A 1 317 ? 132.110 137.212 145.628 1.00 72.03  ? 263 THR A OG1 1 
ATOM   2107  C CG2 . THR A 1 317 ? 133.351 135.186 145.224 1.00 72.30  ? 263 THR A CG2 1 
ATOM   2108  N N   . ILE A 1 318 ? 133.562 139.701 143.568 1.00 70.64  ? 264 ILE A N   1 
ATOM   2109  C CA  . ILE A 1 318 ? 132.913 140.874 142.981 1.00 76.71  ? 264 ILE A CA  1 
ATOM   2110  C C   . ILE A 1 318 ? 133.020 140.860 141.458 1.00 80.56  ? 264 ILE A C   1 
ATOM   2111  O O   . ILE A 1 318 ? 132.033 141.092 140.751 1.00 82.02  ? 264 ILE A O   1 
ATOM   2112  C CB  . ILE A 1 318 ? 133.502 142.168 143.573 1.00 69.42  ? 264 ILE A CB  1 
ATOM   2113  C CG1 . ILE A 1 318 ? 132.729 142.583 144.826 1.00 68.16  ? 264 ILE A CG1 1 
ATOM   2114  C CG2 . ILE A 1 318 ? 133.483 143.296 142.553 1.00 66.54  ? 264 ILE A CG2 1 
ATOM   2115  C CD1 . ILE A 1 318 ? 133.172 143.906 145.405 1.00 67.39  ? 264 ILE A CD1 1 
ATOM   2116  N N   . ASN A 1 319 ? 134.206 140.578 140.927 1.00 77.48  ? 265 ASN A N   1 
ATOM   2117  C CA  . ASN A 1 319 ? 134.470 140.748 139.502 1.00 79.33  ? 265 ASN A CA  1 
ATOM   2118  C C   . ASN A 1 319 ? 134.998 139.479 138.839 1.00 82.55  ? 265 ASN A C   1 
ATOM   2119  O O   . ASN A 1 319 ? 135.990 139.507 138.107 1.00 81.80  ? 265 ASN A O   1 
ATOM   2120  C CB  . ASN A 1 319 ? 135.433 141.905 139.268 1.00 72.70  ? 265 ASN A CB  1 
ATOM   2121  C CG  . ASN A 1 319 ? 134.720 143.231 139.128 1.00 78.03  ? 265 ASN A CG  1 
ATOM   2122  O OD1 . ASN A 1 319 ? 133.503 143.313 139.293 1.00 80.82  ? 265 ASN A OD1 1 
ATOM   2123  N ND2 . ASN A 1 319 ? 135.473 144.280 138.824 1.00 83.65  ? 265 ASN A ND2 1 
ATOM   2124  N N   . THR A 1 320 ? 134.335 138.349 139.084 1.00 79.45  ? 266 THR A N   1 
ATOM   2125  C CA  . THR A 1 320 ? 134.619 137.155 138.298 1.00 78.81  ? 266 THR A CA  1 
ATOM   2126  C C   . THR A 1 320 ? 134.123 137.306 136.865 1.00 82.36  ? 266 THR A C   1 
ATOM   2127  O O   . THR A 1 320 ? 134.540 136.551 135.980 1.00 86.17  ? 266 THR A O   1 
ATOM   2128  C CB  . THR A 1 320 ? 133.992 135.927 138.956 1.00 79.29  ? 266 THR A CB  1 
ATOM   2129  O OG1 . THR A 1 320 ? 132.596 136.159 139.174 1.00 80.56  ? 266 THR A OG1 1 
ATOM   2130  C CG2 . THR A 1 320 ? 134.668 135.637 140.287 1.00 77.89  ? 266 THR A CG2 1 
ATOM   2131  N N   . HIS A 1 321 ? 133.240 138.277 136.618 1.00 84.08  ? 267 HIS A N   1 
ATOM   2132  C CA  . HIS A 1 321 ? 132.679 138.529 135.297 1.00 86.92  ? 267 HIS A CA  1 
ATOM   2133  C C   . HIS A 1 321 ? 133.625 139.295 134.376 1.00 87.55  ? 267 HIS A C   1 
ATOM   2134  O O   . HIS A 1 321 ? 133.191 139.756 133.315 1.00 87.34  ? 267 HIS A O   1 
ATOM   2135  C CB  . HIS A 1 321 ? 131.354 139.287 135.426 1.00 88.33  ? 267 HIS A CB  1 
ATOM   2136  C CG  . HIS A 1 321 ? 131.470 140.589 136.157 1.00 88.12  ? 267 HIS A CG  1 
ATOM   2137  N ND1 . HIS A 1 321 ? 132.039 141.712 135.596 1.00 87.54  ? 267 HIS A ND1 1 
ATOM   2138  C CD2 . HIS A 1 321 ? 131.089 140.946 137.407 1.00 86.97  ? 267 HIS A CD2 1 
ATOM   2139  C CE1 . HIS A 1 321 ? 132.003 142.703 136.468 1.00 86.39  ? 267 HIS A CE1 1 
ATOM   2140  N NE2 . HIS A 1 321 ? 131.432 142.265 137.574 1.00 83.84  ? 267 HIS A NE2 1 
ATOM   2141  N N   . LEU A 1 322 ? 134.897 139.447 134.749 1.00 88.36  ? 268 LEU A N   1 
ATOM   2142  C CA  . LEU A 1 322 ? 135.872 140.116 133.902 1.00 89.21  ? 268 LEU A CA  1 
ATOM   2143  C C   . LEU A 1 322 ? 136.851 139.167 133.228 1.00 88.68  ? 268 LEU A C   1 
ATOM   2144  O O   . LEU A 1 322 ? 137.583 139.600 132.331 1.00 89.12  ? 268 LEU A O   1 
ATOM   2145  C CB  . LEU A 1 322 ? 136.670 141.154 134.708 1.00 84.67  ? 268 LEU A CB  1 
ATOM   2146  C CG  . LEU A 1 322 ? 135.887 142.309 135.333 1.00 86.27  ? 268 LEU A CG  1 
ATOM   2147  C CD1 . LEU A 1 322 ? 136.841 143.333 135.928 1.00 78.60  ? 268 LEU A CD1 1 
ATOM   2148  C CD2 . LEU A 1 322 ? 134.962 142.957 134.313 1.00 84.54  ? 268 LEU A CD2 1 
ATOM   2149  N N   . ARG A 1 323 ? 136.890 137.895 133.628 1.00 90.48  ? 269 ARG A N   1 
ATOM   2150  C CA  . ARG A 1 323 ? 137.787 136.945 132.984 1.00 93.32  ? 269 ARG A CA  1 
ATOM   2151  C C   . ARG A 1 323 ? 137.262 136.497 131.628 1.00 94.40  ? 269 ARG A C   1 
ATOM   2152  O O   . ARG A 1 323 ? 138.013 135.914 130.838 1.00 97.11  ? 269 ARG A O   1 
ATOM   2153  C CB  . ARG A 1 323 ? 138.006 135.732 133.889 1.00 96.73  ? 269 ARG A CB  1 
ATOM   2154  C CG  . ARG A 1 323 ? 136.747 134.923 134.151 1.00 96.60  ? 269 ARG A CG  1 
ATOM   2155  C CD  . ARG A 1 323 ? 137.019 133.725 135.049 1.00 96.28  ? 269 ARG A CD  1 
ATOM   2156  N NE  . ARG A 1 323 ? 137.434 134.121 136.389 1.00 103.63 ? 269 ARG A NE  1 
ATOM   2157  C CZ  . ARG A 1 323 ? 138.686 134.096 136.826 1.00 107.60 ? 269 ARG A CZ  1 
ATOM   2158  N NH1 . ARG A 1 323 ? 139.679 133.688 136.053 1.00 107.16 ? 269 ARG A NH1 1 
ATOM   2159  N NH2 . ARG A 1 323 ? 138.947 134.488 138.069 1.00 104.87 ? 269 ARG A NH2 1 
ATOM   2160  N N   . GLU A 1 324 ? 135.986 136.753 131.342 1.00 92.56  ? 270 GLU A N   1 
ATOM   2161  C CA  . GLU A 1 324 ? 135.398 136.380 130.064 1.00 97.27  ? 270 GLU A CA  1 
ATOM   2162  C C   . GLU A 1 324 ? 135.241 137.560 129.115 1.00 93.03  ? 270 GLU A C   1 
ATOM   2163  O O   . GLU A 1 324 ? 135.222 137.360 127.895 1.00 92.92  ? 270 GLU A O   1 
ATOM   2164  C CB  . GLU A 1 324 ? 134.035 135.718 130.292 1.00 101.84 ? 270 GLU A CB  1 
ATOM   2165  C CG  . GLU A 1 324 ? 133.419 135.094 129.051 1.00 110.91 ? 270 GLU A CG  1 
ATOM   2166  C CD  . GLU A 1 324 ? 132.165 134.302 129.362 1.00 117.59 ? 270 GLU A CD  1 
ATOM   2167  O OE1 . GLU A 1 324 ? 131.920 134.020 130.553 1.00 119.14 ? 270 GLU A OE1 1 
ATOM   2168  O OE2 . GLU A 1 324 ? 131.425 133.963 128.415 1.00 118.81 ? 270 GLU A OE2 1 
ATOM   2169  N N   . THR A 1 325 ? 135.146 138.780 129.641 1.00 87.96  ? 271 THR A N   1 
ATOM   2170  C CA  . THR A 1 325 ? 134.922 139.971 128.835 1.00 84.11  ? 271 THR A CA  1 
ATOM   2171  C C   . THR A 1 325 ? 136.214 140.653 128.406 1.00 83.59  ? 271 THR A C   1 
ATOM   2172  O O   . THR A 1 325 ? 136.159 141.697 127.749 1.00 83.52  ? 271 THR A O   1 
ATOM   2173  C CB  . THR A 1 325 ? 134.049 140.965 129.602 1.00 90.83  ? 271 THR A CB  1 
ATOM   2174  O OG1 . THR A 1 325 ? 134.746 141.403 130.775 1.00 88.83  ? 271 THR A OG1 1 
ATOM   2175  C CG2 . THR A 1 325 ? 132.739 140.315 130.013 1.00 94.01  ? 271 THR A CG2 1 
ATOM   2176  N N   . LEU A 1 326 ? 137.365 140.102 128.760 1.00 82.75  ? 272 LEU A N   1 
ATOM   2177  C CA  . LEU A 1 326 ? 138.653 140.702 128.457 1.00 77.34  ? 272 LEU A CA  1 
ATOM   2178  C C   . LEU A 1 326 ? 139.609 139.655 127.911 1.00 76.62  ? 272 LEU A C   1 
ATOM   2179  O O   . LEU A 1 326 ? 139.467 138.461 128.197 1.00 77.24  ? 272 LEU A O   1 
ATOM   2180  C CB  . LEU A 1 326 ? 139.260 141.359 129.706 1.00 72.83  ? 272 LEU A CB  1 
ATOM   2181  C CG  . LEU A 1 326 ? 138.607 142.672 130.134 1.00 69.39  ? 272 LEU A CG  1 
ATOM   2182  C CD1 . LEU A 1 326 ? 139.220 143.181 131.425 1.00 73.21  ? 272 LEU A CD1 1 
ATOM   2183  C CD2 . LEU A 1 326 ? 138.742 143.706 129.030 1.00 63.73  ? 272 LEU A CD2 1 
ATOM   2184  N N   . PRO A 1 327 ? 140.590 140.069 127.116 1.00 77.60  ? 273 PRO A N   1 
ATOM   2185  C CA  . PRO A 1 327 ? 141.606 139.132 126.634 1.00 79.47  ? 273 PRO A CA  1 
ATOM   2186  C C   . PRO A 1 327 ? 142.665 138.869 127.697 1.00 75.51  ? 273 PRO A C   1 
ATOM   2187  O O   . PRO A 1 327 ? 142.587 139.340 128.832 1.00 74.04  ? 273 PRO A O   1 
ATOM   2188  C CB  . PRO A 1 327 ? 142.204 139.858 125.427 1.00 77.68  ? 273 PRO A CB  1 
ATOM   2189  C CG  . PRO A 1 327 ? 142.053 141.298 125.769 1.00 76.00  ? 273 PRO A CG  1 
ATOM   2190  C CD  . PRO A 1 327 ? 140.750 141.407 126.519 1.00 79.00  ? 273 PRO A CD  1 
ATOM   2191  N N   . LYS A 1 328 ? 143.671 138.095 127.302 1.00 74.31  ? 274 LYS A N   1 
ATOM   2192  C CA  . LYS A 1 328 ? 144.785 137.782 128.186 1.00 72.26  ? 274 LYS A CA  1 
ATOM   2193  C C   . LYS A 1 328 ? 145.895 138.805 127.981 1.00 74.43  ? 274 LYS A C   1 
ATOM   2194  O O   . LYS A 1 328 ? 146.622 138.751 126.983 1.00 81.92  ? 274 LYS A O   1 
ATOM   2195  C CB  . LYS A 1 328 ? 145.288 136.365 127.921 1.00 73.65  ? 274 LYS A CB  1 
ATOM   2196  C CG  . LYS A 1 328 ? 144.216 135.300 128.087 1.00 74.71  ? 274 LYS A CG  1 
ATOM   2197  C CD  . LYS A 1 328 ? 144.803 133.900 128.033 1.00 78.36  ? 274 LYS A CD  1 
ATOM   2198  C CE  . LYS A 1 328 ? 143.724 132.850 128.238 1.00 76.99  ? 274 LYS A CE  1 
ATOM   2199  N NZ  . LYS A 1 328 ? 144.282 131.473 128.302 1.00 83.92  ? 274 LYS A NZ  1 
ATOM   2200  N N   . ILE A 1 329 ? 146.031 139.732 128.927 1.00 65.99  ? 275 ILE A N   1 
ATOM   2201  C CA  . ILE A 1 329 ? 147.003 140.819 128.802 1.00 65.85  ? 275 ILE A CA  1 
ATOM   2202  C C   . ILE A 1 329 ? 147.975 140.762 129.963 1.00 70.80  ? 275 ILE A C   1 
ATOM   2203  O O   . ILE A 1 329 ? 147.597 140.526 131.118 1.00 70.80  ? 275 ILE A O   1 
ATOM   2204  C CB  . ILE A 1 329 ? 146.318 142.199 128.766 1.00 65.91  ? 275 ILE A CB  1 
ATOM   2205  C CG1 . ILE A 1 329 ? 145.130 142.227 129.729 1.00 69.03  ? 275 ILE A CG1 1 
ATOM   2206  C CG2 . ILE A 1 329 ? 145.883 142.542 127.352 1.00 63.92  ? 275 ILE A CG2 1 
ATOM   2207  C CD1 . ILE A 1 329 ? 144.330 143.505 129.673 1.00 66.85  ? 275 ILE A CD1 1 
ATOM   2208  N N   . PRO A 1 330 ? 149.261 140.974 129.674 1.00 69.57  ? 276 PRO A N   1 
ATOM   2209  C CA  . PRO A 1 330 ? 150.285 140.863 130.717 1.00 69.85  ? 276 PRO A CA  1 
ATOM   2210  C C   . PRO A 1 330 ? 150.537 142.163 131.465 1.00 73.13  ? 276 PRO A C   1 
ATOM   2211  O O   . PRO A 1 330 ? 151.692 142.575 131.611 1.00 74.62  ? 276 PRO A O   1 
ATOM   2212  C CB  . PRO A 1 330 ? 151.521 140.437 129.925 1.00 67.86  ? 276 PRO A CB  1 
ATOM   2213  C CG  . PRO A 1 330 ? 151.351 141.156 128.623 1.00 67.25  ? 276 PRO A CG  1 
ATOM   2214  C CD  . PRO A 1 330 ? 149.858 141.238 128.355 1.00 64.97  ? 276 PRO A CD  1 
ATOM   2215  N N   . TYR A 1 331 ? 149.481 142.818 131.940 1.00 70.88  ? 277 TYR A N   1 
ATOM   2216  C CA  . TYR A 1 331 ? 149.650 144.031 132.729 1.00 67.30  ? 277 TYR A CA  1 
ATOM   2217  C C   . TYR A 1 331 ? 148.382 144.286 133.527 1.00 66.11  ? 277 TYR A C   1 
ATOM   2218  O O   . TYR A 1 331 ? 147.331 143.692 133.269 1.00 67.14  ? 277 TYR A O   1 
ATOM   2219  C CB  . TYR A 1 331 ? 149.993 145.243 131.856 1.00 70.68  ? 277 TYR A CB  1 
ATOM   2220  C CG  . TYR A 1 331 ? 149.187 145.364 130.584 1.00 68.73  ? 277 TYR A CG  1 
ATOM   2221  C CD1 . TYR A 1 331 ? 147.870 145.799 130.609 1.00 65.53  ? 277 TYR A CD1 1 
ATOM   2222  C CD2 . TYR A 1 331 ? 149.755 145.068 129.354 1.00 67.59  ? 277 TYR A CD2 1 
ATOM   2223  C CE1 . TYR A 1 331 ? 147.137 145.919 129.447 1.00 67.68  ? 277 TYR A CE1 1 
ATOM   2224  C CE2 . TYR A 1 331 ? 149.031 145.186 128.188 1.00 68.37  ? 277 TYR A CE2 1 
ATOM   2225  C CZ  . TYR A 1 331 ? 147.723 145.611 128.239 1.00 71.28  ? 277 TYR A CZ  1 
ATOM   2226  O OH  . TYR A 1 331 ? 146.999 145.730 127.076 1.00 72.75  ? 277 TYR A OH  1 
ATOM   2227  N N   . VAL A 1 332 ? 148.500 145.179 134.503 1.00 64.12  ? 278 VAL A N   1 
ATOM   2228  C CA  . VAL A 1 332 ? 147.406 145.505 135.408 1.00 62.19  ? 278 VAL A CA  1 
ATOM   2229  C C   . VAL A 1 332 ? 146.586 146.640 134.812 1.00 64.56  ? 278 VAL A C   1 
ATOM   2230  O O   . VAL A 1 332 ? 147.133 147.673 134.410 1.00 67.71  ? 278 VAL A O   1 
ATOM   2231  C CB  . VAL A 1 332 ? 147.940 145.889 136.797 1.00 56.99  ? 278 VAL A CB  1 
ATOM   2232  C CG1 . VAL A 1 332 ? 146.797 146.018 137.783 1.00 58.23  ? 278 VAL A CG1 1 
ATOM   2233  C CG2 . VAL A 1 332 ? 148.951 144.870 137.278 1.00 59.73  ? 278 VAL A CG2 1 
ATOM   2234  N N   . LYS A 1 333 ? 145.272 146.446 134.751 0.50 58.34  ? 279 LYS A N   1 
ATOM   2235  C CA  . LYS A 1 333 ? 144.354 147.506 134.373 0.50 54.22  ? 279 LYS A CA  1 
ATOM   2236  C C   . LYS A 1 333 ? 144.064 148.394 135.581 0.50 55.75  ? 279 LYS A C   1 
ATOM   2237  O O   . LYS A 1 333 ? 144.556 148.165 136.688 0.50 58.90  ? 279 LYS A O   1 
ATOM   2238  C CB  . LYS A 1 333 ? 143.071 146.910 133.802 1.00 51.60  ? 279 LYS A CB  1 
ATOM   2239  C CG  . LYS A 1 333 ? 143.278 146.134 132.517 1.00 55.72  ? 279 LYS A CG  1 
ATOM   2240  C CD  . LYS A 1 333 ? 142.345 144.941 132.433 1.00 56.63  ? 279 LYS A CD  1 
ATOM   2241  C CE  . LYS A 1 333 ? 142.728 143.882 133.452 1.00 62.79  ? 279 LYS A CE  1 
ATOM   2242  N NZ  . LYS A 1 333 ? 141.865 142.674 133.365 1.00 72.67  ? 279 LYS A NZ  1 
ATOM   2243  N N   . ALA A 1 334 ? 143.246 149.427 135.371 1.00 53.70  ? 280 ALA A N   1 
ATOM   2244  C CA  . ALA A 1 334 ? 142.866 150.291 136.484 1.00 53.91  ? 280 ALA A CA  1 
ATOM   2245  C C   . ALA A 1 334 ? 141.849 149.606 137.387 1.00 54.95  ? 280 ALA A C   1 
ATOM   2246  O O   . ALA A 1 334 ? 141.877 149.779 138.613 1.00 61.46  ? 280 ALA A O   1 
ATOM   2247  C CB  . ALA A 1 334 ? 142.313 151.614 135.960 1.00 56.12  ? 280 ALA A CB  1 
ATOM   2248  N N   . ILE A 1 335 ? 140.945 148.822 136.799 1.00 50.69  ? 281 ILE A N   1 
ATOM   2249  C CA  . ILE A 1 335 ? 139.960 148.105 137.598 1.00 53.60  ? 281 ILE A CA  1 
ATOM   2250  C C   . ILE A 1 335 ? 140.639 147.064 138.480 1.00 59.46  ? 281 ILE A C   1 
ATOM   2251  O O   . ILE A 1 335 ? 140.250 146.871 139.639 1.00 63.06  ? 281 ILE A O   1 
ATOM   2252  C CB  . ILE A 1 335 ? 138.889 147.484 136.680 1.00 49.75  ? 281 ILE A CB  1 
ATOM   2253  C CG1 . ILE A 1 335 ? 137.825 146.764 137.505 1.00 58.11  ? 281 ILE A CG1 1 
ATOM   2254  C CG2 . ILE A 1 335 ? 139.518 146.551 135.658 1.00 55.79  ? 281 ILE A CG2 1 
ATOM   2255  C CD1 . ILE A 1 335 ? 137.028 147.685 138.391 1.00 57.05  ? 281 ILE A CD1 1 
ATOM   2256  N N   . ASP A 1 336 ? 141.672 146.394 137.963 1.00 58.71  ? 282 ASP A N   1 
ATOM   2257  C CA  . ASP A 1 336 ? 142.428 145.454 138.783 1.00 55.50  ? 282 ASP A CA  1 
ATOM   2258  C C   . ASP A 1 336 ? 143.128 146.172 139.928 1.00 56.40  ? 282 ASP A C   1 
ATOM   2259  O O   . ASP A 1 336 ? 143.182 145.660 141.050 1.00 62.60  ? 282 ASP A O   1 
ATOM   2260  C CB  . ASP A 1 336 ? 143.438 144.691 137.926 1.00 63.27  ? 282 ASP A CB  1 
ATOM   2261  C CG  . ASP A 1 336 ? 142.777 143.711 136.978 1.00 74.90  ? 282 ASP A CG  1 
ATOM   2262  O OD1 . ASP A 1 336 ? 141.543 143.787 136.805 1.00 77.80  ? 282 ASP A OD1 1 
ATOM   2263  O OD2 . ASP A 1 336 ? 143.493 142.859 136.411 1.00 80.15  ? 282 ASP A OD2 1 
ATOM   2264  N N   . MET A 1 337 ? 143.676 147.361 139.663 1.00 53.63  ? 283 MET A N   1 
ATOM   2265  C CA  . MET A 1 337 ? 144.304 148.140 140.727 1.00 55.79  ? 283 MET A CA  1 
ATOM   2266  C C   . MET A 1 337 ? 143.305 148.496 141.821 1.00 51.97  ? 283 MET A C   1 
ATOM   2267  O O   . MET A 1 337 ? 143.601 148.362 143.015 1.00 56.54  ? 283 MET A O   1 
ATOM   2268  C CB  . MET A 1 337 ? 144.928 149.412 140.153 1.00 58.18  ? 283 MET A CB  1 
ATOM   2269  C CG  . MET A 1 337 ? 146.235 149.194 139.423 1.00 68.14  ? 283 MET A CG  1 
ATOM   2270  S SD  . MET A 1 337 ? 147.530 148.578 140.512 1.00 104.57 ? 283 MET A SD  1 
ATOM   2271  C CE  . MET A 1 337 ? 147.524 149.836 141.786 1.00 81.78  ? 283 MET A CE  1 
ATOM   2272  N N   . TYR A 1 338 ? 142.114 148.951 141.433 1.00 49.98  ? 284 TYR A N   1 
ATOM   2273  C CA  . TYR A 1 338 ? 141.114 149.323 142.429 1.00 49.70  ? 284 TYR A CA  1 
ATOM   2274  C C   . TYR A 1 338 ? 140.667 148.109 143.235 1.00 53.24  ? 284 TYR A C   1 
ATOM   2275  O O   . TYR A 1 338 ? 140.520 148.183 144.464 1.00 63.13  ? 284 TYR A O   1 
ATOM   2276  C CB  . TYR A 1 338 ? 139.922 149.996 141.749 1.00 51.93  ? 284 TYR A CB  1 
ATOM   2277  C CG  . TYR A 1 338 ? 139.022 150.745 142.701 1.00 58.19  ? 284 TYR A CG  1 
ATOM   2278  C CD1 . TYR A 1 338 ? 139.400 151.977 143.216 1.00 59.79  ? 284 TYR A CD1 1 
ATOM   2279  C CD2 . TYR A 1 338 ? 137.792 150.227 143.079 1.00 55.40  ? 284 TYR A CD2 1 
ATOM   2280  C CE1 . TYR A 1 338 ? 138.583 152.669 144.082 1.00 55.33  ? 284 TYR A CE1 1 
ATOM   2281  C CE2 . TYR A 1 338 ? 136.968 150.915 143.946 1.00 52.56  ? 284 TYR A CE2 1 
ATOM   2282  C CZ  . TYR A 1 338 ? 137.370 152.136 144.443 1.00 53.89  ? 284 TYR A CZ  1 
ATOM   2283  O OH  . TYR A 1 338 ? 136.561 152.832 145.307 1.00 61.62  ? 284 TYR A OH  1 
ATOM   2284  N N   . LEU A 1 339 ? 140.447 146.977 142.560 1.00 50.81  ? 285 LEU A N   1 
ATOM   2285  C CA  . LEU A 1 339 ? 140.048 145.763 143.264 1.00 53.17  ? 285 LEU A CA  1 
ATOM   2286  C C   . LEU A 1 339 ? 141.135 145.295 144.222 1.00 53.00  ? 285 LEU A C   1 
ATOM   2287  O O   . LEU A 1 339 ? 140.841 144.870 145.344 1.00 56.17  ? 285 LEU A O   1 
ATOM   2288  C CB  . LEU A 1 339 ? 139.713 144.658 142.266 1.00 59.05  ? 285 LEU A CB  1 
ATOM   2289  C CG  . LEU A 1 339 ? 138.416 144.810 141.477 1.00 66.09  ? 285 LEU A CG  1 
ATOM   2290  C CD1 . LEU A 1 339 ? 138.246 143.627 140.546 1.00 65.51  ? 285 LEU A CD1 1 
ATOM   2291  C CD2 . LEU A 1 339 ? 137.232 144.930 142.419 1.00 63.69  ? 285 LEU A CD2 1 
ATOM   2292  N N   . MET A 1 340 ? 142.397 145.359 143.794 1.00 53.02  ? 286 MET A N   1 
ATOM   2293  C CA  . MET A 1 340 ? 143.499 144.966 144.663 1.00 54.11  ? 286 MET A CA  1 
ATOM   2294  C C   . MET A 1 340 ? 143.579 145.872 145.884 1.00 55.83  ? 286 MET A C   1 
ATOM   2295  O O   . MET A 1 340 ? 143.809 145.403 147.002 1.00 59.49  ? 286 MET A O   1 
ATOM   2296  C CB  . MET A 1 340 ? 144.813 144.985 143.882 1.00 54.64  ? 286 MET A CB  1 
ATOM   2297  C CG  . MET A 1 340 ? 144.974 143.818 142.920 1.00 62.14  ? 286 MET A CG  1 
ATOM   2298  S SD  . MET A 1 340 ? 146.202 144.118 141.634 1.00 84.05  ? 286 MET A SD  1 
ATOM   2299  C CE  . MET A 1 340 ? 147.638 144.543 142.618 1.00 76.45  ? 286 MET A CE  1 
ATOM   2300  N N   . GLY A 1 341 ? 143.380 147.176 145.690 1.00 53.08  ? 287 GLY A N   1 
ATOM   2301  C CA  . GLY A 1 341 ? 143.385 148.086 146.825 1.00 49.54  ? 287 GLY A CA  1 
ATOM   2302  C C   . GLY A 1 341 ? 142.277 147.785 147.817 1.00 51.49  ? 287 GLY A C   1 
ATOM   2303  O O   . GLY A 1 341 ? 142.501 147.745 149.031 1.00 60.04  ? 287 GLY A O   1 
ATOM   2304  N N   . CYS A 1 342 ? 141.062 147.563 147.312 1.00 47.48  ? 288 CYS A N   1 
ATOM   2305  C CA  . CYS A 1 342 ? 139.943 147.265 148.204 1.00 50.05  ? 288 CYS A CA  1 
ATOM   2306  C C   . CYS A 1 342 ? 140.156 145.944 148.938 1.00 58.19  ? 288 CYS A C   1 
ATOM   2307  O O   . CYS A 1 342 ? 139.842 145.825 150.133 1.00 62.57  ? 288 CYS A O   1 
ATOM   2308  C CB  . CYS A 1 342 ? 138.636 147.240 147.417 1.00 49.49  ? 288 CYS A CB  1 
ATOM   2309  S SG  . CYS A 1 342 ? 138.206 148.815 146.648 1.00 70.01  ? 288 CYS A SG  1 
ATOM   2310  N N   . PHE A 1 343 ? 140.684 144.937 148.238 1.00 58.87  ? 289 PHE A N   1 
ATOM   2311  C CA  . PHE A 1 343 ? 140.977 143.659 148.875 1.00 55.60  ? 289 PHE A CA  1 
ATOM   2312  C C   . PHE A 1 343 ? 142.034 143.825 149.959 1.00 55.88  ? 289 PHE A C   1 
ATOM   2313  O O   . PHE A 1 343 ? 141.938 143.229 151.037 1.00 58.58  ? 289 PHE A O   1 
ATOM   2314  C CB  . PHE A 1 343 ? 141.428 142.641 147.828 1.00 51.76  ? 289 PHE A CB  1 
ATOM   2315  C CG  . PHE A 1 343 ? 141.736 141.290 148.397 1.00 56.91  ? 289 PHE A CG  1 
ATOM   2316  C CD1 . PHE A 1 343 ? 140.737 140.346 148.550 1.00 63.47  ? 289 PHE A CD1 1 
ATOM   2317  C CD2 . PHE A 1 343 ? 143.024 140.963 148.782 1.00 60.51  ? 289 PHE A CD2 1 
ATOM   2318  C CE1 . PHE A 1 343 ? 141.018 139.104 149.074 1.00 63.64  ? 289 PHE A CE1 1 
ATOM   2319  C CE2 . PHE A 1 343 ? 143.309 139.724 149.308 1.00 62.56  ? 289 PHE A CE2 1 
ATOM   2320  C CZ  . PHE A 1 343 ? 142.305 138.792 149.453 1.00 63.81  ? 289 PHE A CZ  1 
ATOM   2321  N N   . VAL A 1 344 ? 143.064 144.627 149.681 1.00 53.66  ? 290 VAL A N   1 
ATOM   2322  C CA  . VAL A 1 344 ? 144.085 144.895 150.687 1.00 53.13  ? 290 VAL A CA  1 
ATOM   2323  C C   . VAL A 1 344 ? 143.469 145.553 151.908 1.00 52.26  ? 290 VAL A C   1 
ATOM   2324  O O   . VAL A 1 344 ? 143.799 145.201 153.044 1.00 55.35  ? 290 VAL A O   1 
ATOM   2325  C CB  . VAL A 1 344 ? 145.217 145.754 150.087 1.00 51.82  ? 290 VAL A CB  1 
ATOM   2326  C CG1 . VAL A 1 344 ? 146.079 146.344 151.187 1.00 50.51  ? 290 VAL A CG1 1 
ATOM   2327  C CG2 . VAL A 1 344 ? 146.069 144.916 149.152 1.00 53.11  ? 290 VAL A CG2 1 
ATOM   2328  N N   . PHE A 1 345 ? 142.550 146.497 151.702 1.00 50.53  ? 291 PHE A N   1 
ATOM   2329  C CA  . PHE A 1 345 ? 141.939 147.173 152.843 1.00 52.65  ? 291 PHE A CA  1 
ATOM   2330  C C   . PHE A 1 345 ? 141.084 146.228 153.685 1.00 56.22  ? 291 PHE A C   1 
ATOM   2331  O O   . PHE A 1 345 ? 141.162 146.256 154.920 1.00 61.93  ? 291 PHE A O   1 
ATOM   2332  C CB  . PHE A 1 345 ? 141.112 148.367 152.372 1.00 50.85  ? 291 PHE A CB  1 
ATOM   2333  C CG  . PHE A 1 345 ? 141.872 149.660 152.374 1.00 54.09  ? 291 PHE A CG  1 
ATOM   2334  C CD1 . PHE A 1 345 ? 142.614 150.044 151.272 1.00 54.72  ? 291 PHE A CD1 1 
ATOM   2335  C CD2 . PHE A 1 345 ? 141.853 150.486 153.484 1.00 57.71  ? 291 PHE A CD2 1 
ATOM   2336  C CE1 . PHE A 1 345 ? 143.318 151.231 151.274 1.00 55.69  ? 291 PHE A CE1 1 
ATOM   2337  C CE2 . PHE A 1 345 ? 142.554 151.674 153.492 1.00 62.98  ? 291 PHE A CE2 1 
ATOM   2338  C CZ  . PHE A 1 345 ? 143.288 152.046 152.385 1.00 61.24  ? 291 PHE A CZ  1 
ATOM   2339  N N   . VAL A 1 346 ? 140.271 145.380 153.051 1.00 52.62  ? 292 VAL A N   1 
ATOM   2340  C CA  . VAL A 1 346 ? 139.440 144.471 153.841 1.00 54.60  ? 292 VAL A CA  1 
ATOM   2341  C C   . VAL A 1 346 ? 140.303 143.418 154.539 1.00 59.32  ? 292 VAL A C   1 
ATOM   2342  O O   . VAL A 1 346 ? 140.043 143.041 155.693 1.00 59.79  ? 292 VAL A O   1 
ATOM   2343  C CB  . VAL A 1 346 ? 138.338 143.834 152.975 1.00 53.68  ? 292 VAL A CB  1 
ATOM   2344  C CG1 . VAL A 1 346 ? 137.360 144.898 152.510 1.00 58.53  ? 292 VAL A CG1 1 
ATOM   2345  C CG2 . VAL A 1 346 ? 138.925 143.104 151.791 1.00 60.10  ? 292 VAL A CG2 1 
ATOM   2346  N N   . PHE A 1 347 ? 141.355 142.944 153.866 1.00 58.33  ? 293 PHE A N   1 
ATOM   2347  C CA  . PHE A 1 347 ? 142.268 141.996 154.493 1.00 55.06  ? 293 PHE A CA  1 
ATOM   2348  C C   . PHE A 1 347 ? 142.984 142.631 155.677 1.00 58.86  ? 293 PHE A C   1 
ATOM   2349  O O   . PHE A 1 347 ? 143.222 141.972 156.696 1.00 66.93  ? 293 PHE A O   1 
ATOM   2350  C CB  . PHE A 1 347 ? 143.272 141.488 153.461 1.00 57.95  ? 293 PHE A CB  1 
ATOM   2351  C CG  . PHE A 1 347 ? 144.068 140.306 153.921 1.00 62.88  ? 293 PHE A CG  1 
ATOM   2352  C CD1 . PHE A 1 347 ? 143.573 139.023 153.770 1.00 66.34  ? 293 PHE A CD1 1 
ATOM   2353  C CD2 . PHE A 1 347 ? 145.316 140.474 154.496 1.00 65.37  ? 293 PHE A CD2 1 
ATOM   2354  C CE1 . PHE A 1 347 ? 144.302 137.930 154.189 1.00 71.10  ? 293 PHE A CE1 1 
ATOM   2355  C CE2 . PHE A 1 347 ? 146.051 139.384 154.917 1.00 68.07  ? 293 PHE A CE2 1 
ATOM   2356  C CZ  . PHE A 1 347 ? 145.543 138.111 154.763 1.00 70.46  ? 293 PHE A CZ  1 
ATOM   2357  N N   . LEU A 1 348 ? 143.332 143.914 155.565 1.00 56.86  ? 294 LEU A N   1 
ATOM   2358  C CA  . LEU A 1 348 ? 143.964 144.606 156.680 1.00 57.72  ? 294 LEU A CA  1 
ATOM   2359  C C   . LEU A 1 348 ? 142.990 144.830 157.826 1.00 60.13  ? 294 LEU A C   1 
ATOM   2360  O O   . LEU A 1 348 ? 143.401 144.823 158.986 1.00 66.39  ? 294 LEU A O   1 
ATOM   2361  C CB  . LEU A 1 348 ? 144.555 145.935 156.215 1.00 57.82  ? 294 LEU A CB  1 
ATOM   2362  C CG  . LEU A 1 348 ? 145.854 145.834 155.417 1.00 55.87  ? 294 LEU A CG  1 
ATOM   2363  C CD1 . LEU A 1 348 ? 146.359 147.215 155.042 1.00 59.60  ? 294 LEU A CD1 1 
ATOM   2364  C CD2 . LEU A 1 348 ? 146.896 145.079 156.219 1.00 52.04  ? 294 LEU A CD2 1 
ATOM   2365  N N   . ALA A 1 349 ? 141.705 145.029 157.531 1.00 57.16  ? 295 ALA A N   1 
ATOM   2366  C CA  . ALA A 1 349 ? 140.715 145.071 158.605 1.00 62.67  ? 295 ALA A CA  1 
ATOM   2367  C C   . ALA A 1 349 ? 140.653 143.739 159.346 1.00 66.48  ? 295 ALA A C   1 
ATOM   2368  O O   . ALA A 1 349 ? 140.611 143.699 160.587 1.00 73.02  ? 295 ALA A O   1 
ATOM   2369  C CB  . ALA A 1 349 ? 139.342 145.435 158.041 1.00 59.28  ? 295 ALA A CB  1 
ATOM   2370  N N   . LEU A 1 350 ? 140.651 142.633 158.596 1.00 62.12  ? 296 LEU A N   1 
ATOM   2371  C CA  . LEU A 1 350 ? 140.652 141.318 159.232 1.00 62.46  ? 296 LEU A CA  1 
ATOM   2372  C C   . LEU A 1 350 ? 141.904 141.116 160.080 1.00 65.28  ? 296 LEU A C   1 
ATOM   2373  O O   . LEU A 1 350 ? 141.825 140.617 161.209 1.00 71.26  ? 296 LEU A O   1 
ATOM   2374  C CB  . LEU A 1 350 ? 140.537 140.220 158.175 1.00 62.54  ? 296 LEU A CB  1 
ATOM   2375  C CG  . LEU A 1 350 ? 140.533 138.783 158.699 1.00 54.42  ? 296 LEU A CG  1 
ATOM   2376  C CD1 . LEU A 1 350 ? 139.386 138.573 159.673 1.00 57.14  ? 296 LEU A CD1 1 
ATOM   2377  C CD2 . LEU A 1 350 ? 140.448 137.796 157.548 1.00 54.66  ? 296 LEU A CD2 1 
ATOM   2378  N N   . LEU A 1 351 ? 143.069 141.503 159.556 1.00 65.06  ? 297 LEU A N   1 
ATOM   2379  C CA  . LEU A 1 351 ? 144.303 141.403 160.330 1.00 66.70  ? 297 LEU A CA  1 
ATOM   2380  C C   . LEU A 1 351 ? 144.280 142.309 161.553 1.00 73.63  ? 297 LEU A C   1 
ATOM   2381  O O   . LEU A 1 351 ? 144.867 141.972 162.586 1.00 81.97  ? 297 LEU A O   1 
ATOM   2382  C CB  . LEU A 1 351 ? 145.509 141.743 159.457 1.00 62.71  ? 297 LEU A CB  1 
ATOM   2383  C CG  . LEU A 1 351 ? 145.933 140.688 158.441 1.00 65.24  ? 297 LEU A CG  1 
ATOM   2384  C CD1 . LEU A 1 351 ? 147.227 141.109 157.773 1.00 67.77  ? 297 LEU A CD1 1 
ATOM   2385  C CD2 . LEU A 1 351 ? 146.092 139.344 159.123 1.00 71.36  ? 297 LEU A CD2 1 
ATOM   2386  N N   . GLU A 1 352 ? 143.633 143.471 161.450 1.00 71.71  ? 298 GLU A N   1 
ATOM   2387  C CA  . GLU A 1 352 ? 143.490 144.341 162.608 1.00 75.95  ? 298 GLU A CA  1 
ATOM   2388  C C   . GLU A 1 352 ? 142.706 143.646 163.706 1.00 80.79  ? 298 GLU A C   1 
ATOM   2389  O O   . GLU A 1 352 ? 143.102 143.678 164.879 1.00 87.73  ? 298 GLU A O   1 
ATOM   2390  C CB  . GLU A 1 352 ? 142.804 145.647 162.203 1.00 75.72  ? 298 GLU A CB  1 
ATOM   2391  C CG  . GLU A 1 352 ? 142.544 146.612 163.352 1.00 76.75  ? 298 GLU A CG  1 
ATOM   2392  C CD  . GLU A 1 352 ? 141.195 146.399 164.014 1.00 83.09  ? 298 GLU A CD  1 
ATOM   2393  O OE1 . GLU A 1 352 ? 140.423 145.537 163.544 1.00 79.52  ? 298 GLU A OE1 1 
ATOM   2394  O OE2 . GLU A 1 352 ? 140.905 147.096 165.008 1.00 90.01  ? 298 GLU A OE2 1 
ATOM   2395  N N   . TYR A 1 353 ? 141.594 143.002 163.348 1.00 77.53  ? 299 TYR A N   1 
ATOM   2396  C CA  . TYR A 1 353 ? 140.872 142.251 164.369 1.00 84.74  ? 299 TYR A CA  1 
ATOM   2397  C C   . TYR A 1 353 ? 141.718 141.103 164.906 1.00 86.18  ? 299 TYR A C   1 
ATOM   2398  O O   . TYR A 1 353 ? 141.645 140.771 166.096 1.00 88.54  ? 299 TYR A O   1 
ATOM   2399  C CB  . TYR A 1 353 ? 139.544 141.700 163.858 1.00 86.96  ? 299 TYR A CB  1 
ATOM   2400  C CG  . TYR A 1 353 ? 139.030 140.708 164.867 1.00 92.02  ? 299 TYR A CG  1 
ATOM   2401  C CD1 . TYR A 1 353 ? 138.524 141.139 166.083 1.00 94.01  ? 299 TYR A CD1 1 
ATOM   2402  C CD2 . TYR A 1 353 ? 139.137 139.342 164.650 1.00 93.54  ? 299 TYR A CD2 1 
ATOM   2403  C CE1 . TYR A 1 353 ? 138.093 140.244 167.031 1.00 99.15  ? 299 TYR A CE1 1 
ATOM   2404  C CE2 . TYR A 1 353 ? 138.716 138.442 165.595 1.00 96.34  ? 299 TYR A CE2 1 
ATOM   2405  C CZ  . TYR A 1 353 ? 138.191 138.897 166.780 1.00 101.03 ? 299 TYR A CZ  1 
ATOM   2406  O OH  . TYR A 1 353 ? 137.767 137.996 167.721 1.00 101.41 ? 299 TYR A OH  1 
ATOM   2407  N N   . ALA A 1 354 ? 142.494 140.455 164.036 1.00 81.29  ? 300 ALA A N   1 
ATOM   2408  C CA  . ALA A 1 354 ? 143.352 139.366 164.492 1.00 77.35  ? 300 ALA A CA  1 
ATOM   2409  C C   . ALA A 1 354 ? 144.340 139.856 165.542 1.00 86.02  ? 300 ALA A C   1 
ATOM   2410  O O   . ALA A 1 354 ? 144.545 139.200 166.569 1.00 95.39  ? 300 ALA A O   1 
ATOM   2411  C CB  . ALA A 1 354 ? 144.088 138.743 163.308 1.00 73.47  ? 300 ALA A CB  1 
ATOM   2412  N N   . PHE A 1 355 ? 144.948 141.019 165.307 1.00 85.80  ? 301 PHE A N   1 
ATOM   2413  C CA  . PHE A 1 355 ? 145.868 141.593 166.284 1.00 90.54  ? 301 PHE A CA  1 
ATOM   2414  C C   . PHE A 1 355 ? 145.142 141.980 167.568 1.00 92.38  ? 301 PHE A C   1 
ATOM   2415  O O   . PHE A 1 355 ? 145.681 141.808 168.670 1.00 97.52  ? 301 PHE A O   1 
ATOM   2416  C CB  . PHE A 1 355 ? 146.579 142.803 165.681 1.00 93.24  ? 301 PHE A CB  1 
ATOM   2417  C CG  . PHE A 1 355 ? 147.867 143.154 166.366 1.00 100.14 ? 301 PHE A CG  1 
ATOM   2418  C CD1 . PHE A 1 355 ? 149.034 142.471 166.063 1.00 102.68 ? 301 PHE A CD1 1 
ATOM   2419  C CD2 . PHE A 1 355 ? 147.914 144.166 167.308 1.00 97.70  ? 301 PHE A CD2 1 
ATOM   2420  C CE1 . PHE A 1 355 ? 150.222 142.790 166.688 1.00 103.45 ? 301 PHE A CE1 1 
ATOM   2421  C CE2 . PHE A 1 355 ? 149.101 144.491 167.936 1.00 100.52 ? 301 PHE A CE2 1 
ATOM   2422  C CZ  . PHE A 1 355 ? 150.256 143.802 167.626 1.00 104.68 ? 301 PHE A CZ  1 
ATOM   2423  N N   . VAL A 1 356 ? 143.924 142.516 167.444 1.00 89.07  ? 302 VAL A N   1 
ATOM   2424  C CA  . VAL A 1 356 ? 143.139 142.869 168.626 1.00 93.01  ? 302 VAL A CA  1 
ATOM   2425  C C   . VAL A 1 356 ? 142.889 141.635 169.484 1.00 99.98  ? 302 VAL A C   1 
ATOM   2426  O O   . VAL A 1 356 ? 143.059 141.660 170.708 1.00 105.34 ? 302 VAL A O   1 
ATOM   2427  C CB  . VAL A 1 356 ? 141.819 143.544 168.211 1.00 91.43  ? 302 VAL A CB  1 
ATOM   2428  C CG1 . VAL A 1 356 ? 140.795 143.450 169.331 1.00 91.94  ? 302 VAL A CG1 1 
ATOM   2429  C CG2 . VAL A 1 356 ? 142.064 144.995 167.840 1.00 93.12  ? 302 VAL A CG2 1 
ATOM   2430  N N   . ASN A 1 357 ? 142.489 140.533 168.848 1.00 97.50  ? 303 ASN A N   1 
ATOM   2431  C CA  . ASN A 1 357 ? 142.284 139.284 169.576 1.00 96.70  ? 303 ASN A CA  1 
ATOM   2432  C C   . ASN A 1 357 ? 143.588 138.775 170.176 1.00 96.73  ? 303 ASN A C   1 
ATOM   2433  O O   . ASN A 1 357 ? 143.604 138.256 171.299 1.00 98.25  ? 303 ASN A O   1 
ATOM   2434  C CB  . ASN A 1 357 ? 141.673 138.233 168.650 1.00 96.89  ? 303 ASN A CB  1 
ATOM   2435  C CG  . ASN A 1 357 ? 141.953 136.817 169.110 1.00 97.75  ? 303 ASN A CG  1 
ATOM   2436  O OD1 . ASN A 1 357 ? 142.904 136.182 168.655 1.00 98.54  ? 303 ASN A OD1 1 
ATOM   2437  N ND2 . ASN A 1 357 ? 141.127 136.315 170.019 1.00 102.07 ? 303 ASN A ND2 1 
ATOM   2438  N N   . TYR A 1 358 ? 144.691 138.910 169.437 1.00 96.48  ? 304 TYR A N   1 
ATOM   2439  C CA  . TYR A 1 358 ? 145.977 138.409 169.909 1.00 97.66  ? 304 TYR A CA  1 
ATOM   2440  C C   . TYR A 1 358 ? 146.435 139.131 171.170 1.00 106.40 ? 304 TYR A C   1 
ATOM   2441  O O   . TYR A 1 358 ? 146.950 138.500 172.101 1.00 109.15 ? 304 TYR A O   1 
ATOM   2442  C CB  . TYR A 1 358 ? 147.017 138.545 168.797 1.00 97.47  ? 304 TYR A CB  1 
ATOM   2443  C CG  . TYR A 1 358 ? 148.415 138.124 169.185 1.00 101.85 ? 304 TYR A CG  1 
ATOM   2444  C CD1 . TYR A 1 358 ? 148.781 136.786 169.196 1.00 102.96 ? 304 TYR A CD1 1 
ATOM   2445  C CD2 . TYR A 1 358 ? 149.375 139.068 169.521 1.00 104.12 ? 304 TYR A CD2 1 
ATOM   2446  C CE1 . TYR A 1 358 ? 150.062 136.400 169.543 1.00 105.31 ? 304 TYR A CE1 1 
ATOM   2447  C CE2 . TYR A 1 358 ? 150.656 138.692 169.869 1.00 104.07 ? 304 TYR A CE2 1 
ATOM   2448  C CZ  . TYR A 1 358 ? 150.995 137.358 169.878 1.00 104.78 ? 304 TYR A CZ  1 
ATOM   2449  O OH  . TYR A 1 358 ? 152.273 136.982 170.225 1.00 103.16 ? 304 TYR A OH  1 
ATOM   2450  N N   . ILE A 1 359 ? 146.261 140.453 171.224 1.00 108.28 ? 305 ILE A N   1 
ATOM   2451  C CA  . ILE A 1 359 ? 146.728 141.235 172.368 1.00 106.10 ? 305 ILE A CA  1 
ATOM   2452  C C   . ILE A 1 359 ? 145.591 141.617 173.311 1.00 108.67 ? 305 ILE A C   1 
ATOM   2453  O O   . ILE A 1 359 ? 145.773 142.483 174.171 1.00 113.58 ? 305 ILE A O   1 
ATOM   2454  C CB  . ILE A 1 359 ? 147.493 142.490 171.919 1.00 105.59 ? 305 ILE A CB  1 
ATOM   2455  C CG1 . ILE A 1 359 ? 146.553 143.467 171.215 1.00 109.07 ? 305 ILE A CG1 1 
ATOM   2456  C CG2 . ILE A 1 359 ? 148.659 142.114 171.024 1.00 103.27 ? 305 ILE A CG2 1 
ATOM   2457  C CD1 . ILE A 1 359 ? 147.187 144.801 170.913 1.00 109.40 ? 305 ILE A CD1 1 
ATOM   2458  N N   . PHE A 1 360 ? 144.419 140.996 173.168 1.00 107.77 ? 306 PHE A N   1 
ATOM   2459  C CA  . PHE A 1 360 ? 143.293 141.349 174.027 1.00 113.74 ? 306 PHE A CA  1 
ATOM   2460  C C   . PHE A 1 360 ? 143.554 140.981 175.483 1.00 123.23 ? 306 PHE A C   1 
ATOM   2461  O O   . PHE A 1 360 ? 143.218 141.750 176.391 1.00 121.28 ? 306 PHE A O   1 
ATOM   2462  C CB  . PHE A 1 360 ? 142.020 140.671 173.529 1.00 109.27 ? 306 PHE A CB  1 
ATOM   2463  C CG  . PHE A 1 360 ? 140.833 140.895 174.417 1.00 113.44 ? 306 PHE A CG  1 
ATOM   2464  C CD1 . PHE A 1 360 ? 140.196 142.123 174.443 1.00 114.64 ? 306 PHE A CD1 1 
ATOM   2465  C CD2 . PHE A 1 360 ? 140.355 139.879 175.226 1.00 113.01 ? 306 PHE A CD2 1 
ATOM   2466  C CE1 . PHE A 1 360 ? 139.107 142.334 175.261 1.00 114.52 ? 306 PHE A CE1 1 
ATOM   2467  C CE2 . PHE A 1 360 ? 139.263 140.085 176.046 1.00 112.88 ? 306 PHE A CE2 1 
ATOM   2468  C CZ  . PHE A 1 360 ? 138.639 141.315 176.062 1.00 114.13 ? 306 PHE A CZ  1 
ATOM   2469  N N   . PHE A 1 361 ? 144.144 139.809 175.728 1.00 125.96 ? 307 PHE A N   1 
ATOM   2470  C CA  . PHE A 1 361 ? 144.274 139.326 177.099 1.00 126.26 ? 307 PHE A CA  1 
ATOM   2471  C C   . PHE A 1 361 ? 145.289 140.143 177.890 1.00 125.67 ? 307 PHE A C   1 
ATOM   2472  O O   . PHE A 1 361 ? 145.068 140.439 179.070 1.00 122.88 ? 307 PHE A O   1 
ATOM   2473  C CB  . PHE A 1 361 ? 144.654 137.846 177.102 1.00 128.73 ? 307 PHE A CB  1 
ATOM   2474  C CG  . PHE A 1 361 ? 144.363 137.151 178.401 1.00 133.90 ? 307 PHE A CG  1 
ATOM   2475  C CD1 . PHE A 1 361 ? 143.100 136.644 178.662 1.00 135.26 ? 307 PHE A CD1 1 
ATOM   2476  C CD2 . PHE A 1 361 ? 145.348 137.006 179.364 1.00 132.72 ? 307 PHE A CD2 1 
ATOM   2477  C CE1 . PHE A 1 361 ? 142.825 136.005 179.856 1.00 133.59 ? 307 PHE A CE1 1 
ATOM   2478  C CE2 . PHE A 1 361 ? 145.080 136.367 180.561 1.00 131.28 ? 307 PHE A CE2 1 
ATOM   2479  C CZ  . PHE A 1 361 ? 143.816 135.866 180.807 1.00 130.90 ? 307 PHE A CZ  1 
ATOM   2480  N N   . SER A 1 362 ? 146.411 140.508 177.264 1.00 126.48 ? 308 SER A N   1 
ATOM   2481  C CA  . SER A 1 362 ? 147.435 141.267 177.976 1.00 126.42 ? 308 SER A CA  1 
ATOM   2482  C C   . SER A 1 362 ? 146.926 142.645 178.380 1.00 126.81 ? 308 SER A C   1 
ATOM   2483  O O   . SER A 1 362 ? 147.148 143.090 179.512 1.00 127.13 ? 308 SER A O   1 
ATOM   2484  C CB  . SER A 1 362 ? 148.691 141.395 177.115 1.00 116.33 ? 308 SER A CB  1 
ATOM   2485  O OG  . SER A 1 362 ? 148.479 142.297 176.042 1.00 110.90 ? 308 SER A OG  1 
ATOM   2486  N N   . GLN A 1 363 ? 146.242 143.335 177.471 1.00 121.18 ? 309 GLN A N   1 
ATOM   2487  C CA  . GLN A 1 363 ? 145.739 144.671 177.759 1.00 117.80 ? 309 GLN A CA  1 
ATOM   2488  C C   . GLN A 1 363 ? 144.300 144.810 177.281 1.00 117.31 ? 309 GLN A C   1 
ATOM   2489  O O   . GLN A 1 363 ? 144.061 145.002 176.082 1.00 117.02 ? 309 GLN A O   1 
ATOM   2490  C CB  . GLN A 1 363 ? 146.614 145.737 177.097 1.00 119.73 ? 309 GLN A CB  1 
ATOM   2491  C CG  . GLN A 1 363 ? 148.095 145.645 177.423 1.00 121.38 ? 309 GLN A CG  1 
ATOM   2492  C CD  . GLN A 1 363 ? 148.920 146.643 176.635 1.00 121.45 ? 309 GLN A CD  1 
ATOM   2493  O OE1 . GLN A 1 363 ? 148.550 147.810 176.508 1.00 123.34 ? 309 GLN A OE1 1 
ATOM   2494  N NE2 . GLN A 1 363 ? 150.041 146.184 176.090 1.00 114.77 ? 309 GLN A NE2 1 
ATOM   2495  N N   . PRO A 1 364 ? 143.315 144.717 178.180 1.00 120.20 ? 310 PRO A N   1 
ATOM   2496  C CA  . PRO A 1 364 ? 141.919 144.928 177.767 1.00 120.56 ? 310 PRO A CA  1 
ATOM   2497  C C   . PRO A 1 364 ? 141.630 146.339 177.282 1.00 118.10 ? 310 PRO A C   1 
ATOM   2498  O O   . PRO A 1 364 ? 140.628 146.538 176.583 1.00 113.89 ? 310 PRO A O   1 
ATOM   2499  C CB  . PRO A 1 364 ? 141.123 144.604 179.038 1.00 121.55 ? 310 PRO A CB  1 
ATOM   2500  C CG  . PRO A 1 364 ? 142.093 144.810 180.154 1.00 121.55 ? 310 PRO A CG  1 
ATOM   2501  C CD  . PRO A 1 364 ? 143.431 144.404 179.613 1.00 121.69 ? 310 PRO A CD  1 
ATOM   2502  N N   . ALA A 1 365 ? 142.465 147.319 177.627 1.00 116.71 ? 311 ALA A N   1 
ATOM   2503  C CA  . ALA A 1 365 ? 142.286 148.687 177.160 1.00 112.02 ? 311 ALA A CA  1 
ATOM   2504  C C   . ALA A 1 365 ? 142.959 148.958 175.825 1.00 110.61 ? 311 ALA A C   1 
ATOM   2505  O O   . ALA A 1 365 ? 142.462 149.780 175.048 1.00 108.49 ? 311 ALA A O   1 
ATOM   2506  C CB  . ALA A 1 365 ? 142.819 149.678 178.200 1.00 107.57 ? 311 ALA A CB  1 
ATOM   2507  N N   . ARG A 1 366 ? 144.078 148.289 175.537 1.00 111.76 ? 312 ARG A N   1 
ATOM   2508  C CA  . ARG A 1 366 ? 144.760 148.512 174.268 1.00 108.77 ? 312 ARG A CA  1 
ATOM   2509  C C   . ARG A 1 366 ? 143.933 148.015 173.089 1.00 105.98 ? 312 ARG A C   1 
ATOM   2510  O O   . ARG A 1 366 ? 143.992 148.604 172.006 1.00 104.45 ? 312 ARG A O   1 
ATOM   2511  C CB  . ARG A 1 366 ? 146.131 147.840 174.280 1.00 108.09 ? 312 ARG A CB  1 
ATOM   2512  C CG  . ARG A 1 366 ? 146.928 148.033 173.005 1.00 105.71 ? 312 ARG A CG  1 
ATOM   2513  C CD  . ARG A 1 366 ? 148.363 147.584 173.184 1.00 106.08 ? 312 ARG A CD  1 
ATOM   2514  N NE  . ARG A 1 366 ? 149.102 147.615 171.928 1.00 107.56 ? 312 ARG A NE  1 
ATOM   2515  C CZ  . ARG A 1 366 ? 150.403 147.390 171.820 1.00 108.31 ? 312 ARG A CZ  1 
ATOM   2516  N NH1 . ARG A 1 366 ? 151.150 147.132 172.882 1.00 109.89 ? 312 ARG A NH1 1 
ATOM   2517  N NH2 . ARG A 1 366 ? 150.971 147.426 170.618 1.00 107.84 ? 312 ARG A NH2 1 
ATOM   2518  N N   . ALA A 1 367 ? 143.158 146.944 173.276 1.00 107.13 ? 313 ALA A N   1 
ATOM   2519  C CA  . ALA A 1 367 ? 142.273 146.480 172.210 1.00 104.18 ? 313 ALA A CA  1 
ATOM   2520  C C   . ALA A 1 367 ? 141.216 147.528 171.884 1.00 106.21 ? 313 ALA A C   1 
ATOM   2521  O O   . ALA A 1 367 ? 140.942 147.811 170.710 1.00 108.32 ? 313 ALA A O   1 
ATOM   2522  C CB  . ALA A 1 367 ? 141.619 145.159 172.609 1.00 100.13 ? 313 ALA A CB  1 
ATOM   2523  N N   . ALA A 1 368 ? 140.615 148.122 172.917 1.00 105.00 ? 314 ALA A N   1 
ATOM   2524  C CA  . ALA A 1 368 ? 139.641 149.184 172.694 1.00 106.04 ? 314 ALA A CA  1 
ATOM   2525  C C   . ALA A 1 368 ? 140.296 150.398 172.049 1.00 103.82 ? 314 ALA A C   1 
ATOM   2526  O O   . ALA A 1 368 ? 139.701 151.047 171.181 1.00 101.92 ? 314 ALA A O   1 
ATOM   2527  C CB  . ALA A 1 368 ? 138.970 149.569 174.012 1.00 106.84 ? 314 ALA A CB  1 
ATOM   2528  N N   . ALA A 1 369 ? 141.526 150.719 172.461 1.00 104.00 ? 422 ALA A N   1 
ATOM   2529  C CA  . ALA A 1 369 ? 142.242 151.836 171.853 1.00 102.56 ? 422 ALA A CA  1 
ATOM   2530  C C   . ALA A 1 369 ? 142.504 151.586 170.373 1.00 99.52  ? 422 ALA A C   1 
ATOM   2531  O O   . ALA A 1 369 ? 142.349 152.490 169.544 1.00 98.53  ? 422 ALA A O   1 
ATOM   2532  C CB  . ALA A 1 369 ? 143.554 152.085 172.595 1.00 100.77 ? 422 ALA A CB  1 
ATOM   2533  N N   . ILE A 1 370 ? 142.901 150.361 170.024 1.00 97.03  ? 423 ILE A N   1 
ATOM   2534  C CA  . ILE A 1 370 ? 143.158 150.030 168.627 1.00 91.96  ? 423 ILE A CA  1 
ATOM   2535  C C   . ILE A 1 370 ? 141.869 150.086 167.817 1.00 91.60  ? 423 ILE A C   1 
ATOM   2536  O O   . ILE A 1 370 ? 141.858 150.579 166.684 1.00 94.41  ? 423 ILE A O   1 
ATOM   2537  C CB  . ILE A 1 370 ? 143.845 148.657 168.518 1.00 91.72  ? 423 ILE A CB  1 
ATOM   2538  C CG1 . ILE A 1 370 ? 145.291 148.753 169.007 1.00 98.12  ? 423 ILE A CG1 1 
ATOM   2539  C CG2 . ILE A 1 370 ? 143.806 148.147 167.088 1.00 90.67  ? 423 ILE A CG2 1 
ATOM   2540  C CD1 . ILE A 1 370 ? 146.111 147.513 168.737 1.00 100.98 ? 423 ILE A CD1 1 
ATOM   2541  N N   . ASP A 1 371 ? 140.763 149.590 168.379 1.00 90.88  ? 424 ASP A N   1 
ATOM   2542  C CA  . ASP A 1 371 ? 139.486 149.689 167.676 1.00 89.76  ? 424 ASP A CA  1 
ATOM   2543  C C   . ASP A 1 371 ? 139.090 151.144 167.449 1.00 91.64  ? 424 ASP A C   1 
ATOM   2544  O O   . ASP A 1 371 ? 138.667 151.517 166.345 1.00 93.79  ? 424 ASP A O   1 
ATOM   2545  C CB  . ASP A 1 371 ? 138.393 148.957 168.454 1.00 96.58  ? 424 ASP A CB  1 
ATOM   2546  C CG  . ASP A 1 371 ? 138.348 147.476 168.144 1.00 100.56 ? 424 ASP A CG  1 
ATOM   2547  O OD1 . ASP A 1 371 ? 139.163 147.015 167.317 1.00 96.36  ? 424 ASP A OD1 1 
ATOM   2548  O OD2 . ASP A 1 371 ? 137.493 146.772 168.722 1.00 108.01 ? 424 ASP A OD2 1 
ATOM   2549  N N   . ARG A 1 372 ? 139.227 151.982 168.481 1.00 93.18  ? 425 ARG A N   1 
ATOM   2550  C CA  . ARG A 1 372 ? 138.878 153.391 168.341 1.00 93.16  ? 425 ARG A CA  1 
ATOM   2551  C C   . ARG A 1 372 ? 139.744 154.071 167.291 1.00 89.72  ? 425 ARG A C   1 
ATOM   2552  O O   . ARG A 1 372 ? 139.242 154.854 166.477 1.00 89.86  ? 425 ARG A O   1 
ATOM   2553  C CB  . ARG A 1 372 ? 139.009 154.109 169.684 1.00 99.46  ? 425 ARG A CB  1 
ATOM   2554  C CG  . ARG A 1 372 ? 138.006 153.664 170.731 1.00 103.91 ? 425 ARG A CG  1 
ATOM   2555  C CD  . ARG A 1 372 ? 138.014 154.599 171.928 1.00 109.75 ? 425 ARG A CD  1 
ATOM   2556  N NE  . ARG A 1 372 ? 139.368 154.906 172.374 1.00 110.81 ? 425 ARG A NE  1 
ATOM   2557  C CZ  . ARG A 1 372 ? 140.051 154.185 173.252 1.00 114.46 ? 425 ARG A CZ  1 
ATOM   2558  N NH1 . ARG A 1 372 ? 139.539 153.095 173.799 1.00 116.04 ? 425 ARG A NH1 1 
ATOM   2559  N NH2 . ARG A 1 372 ? 141.279 154.567 173.589 1.00 115.10 ? 425 ARG A NH2 1 
ATOM   2560  N N   . TRP A 1 373 ? 141.050 153.788 167.293 1.00 87.39  ? 426 TRP A N   1 
ATOM   2561  C CA  . TRP A 1 373 ? 141.918 154.372 166.277 1.00 85.08  ? 426 TRP A CA  1 
ATOM   2562  C C   . TRP A 1 373 ? 141.527 153.904 164.884 1.00 83.41  ? 426 TRP A C   1 
ATOM   2563  O O   . TRP A 1 373 ? 141.448 154.713 163.955 1.00 84.57  ? 426 TRP A O   1 
ATOM   2564  C CB  . TRP A 1 373 ? 143.384 154.038 166.555 1.00 86.07  ? 426 TRP A CB  1 
ATOM   2565  C CG  . TRP A 1 373 ? 144.092 154.999 167.475 1.00 95.92  ? 426 TRP A CG  1 
ATOM   2566  C CD1 . TRP A 1 373 ? 145.043 154.684 168.401 1.00 101.07 ? 426 TRP A CD1 1 
ATOM   2567  C CD2 . TRP A 1 373 ? 143.914 156.425 167.557 1.00 102.89 ? 426 TRP A CD2 1 
ATOM   2568  N NE1 . TRP A 1 373 ? 145.468 155.815 169.052 1.00 102.14 ? 426 TRP A NE1 1 
ATOM   2569  C CE2 . TRP A 1 373 ? 144.790 156.897 168.554 1.00 104.40 ? 426 TRP A CE2 1 
ATOM   2570  C CE3 . TRP A 1 373 ? 143.102 157.347 166.885 1.00 102.74 ? 426 TRP A CE3 1 
ATOM   2571  C CZ2 . TRP A 1 373 ? 144.875 158.244 168.897 1.00 103.21 ? 426 TRP A CZ2 1 
ATOM   2572  C CZ3 . TRP A 1 373 ? 143.185 158.681 167.229 1.00 103.66 ? 426 TRP A CZ3 1 
ATOM   2573  C CH2 . TRP A 1 373 ? 144.066 159.118 168.224 1.00 104.70 ? 426 TRP A CH2 1 
ATOM   2574  N N   . SER A 1 374 ? 141.252 152.606 164.727 1.00 79.40  ? 427 SER A N   1 
ATOM   2575  C CA  . SER A 1 374 ? 140.925 152.067 163.413 1.00 73.86  ? 427 SER A CA  1 
ATOM   2576  C C   . SER A 1 374 ? 139.658 152.698 162.859 1.00 76.67  ? 427 SER A C   1 
ATOM   2577  O O   . SER A 1 374 ? 139.597 153.024 161.664 1.00 75.93  ? 427 SER A O   1 
ATOM   2578  C CB  . SER A 1 374 ? 140.777 150.550 163.492 1.00 70.60  ? 427 SER A CB  1 
ATOM   2579  O OG  . SER A 1 374 ? 142.007 149.941 163.838 1.00 73.76  ? 427 SER A OG  1 
ATOM   2580  N N   . ARG A 1 375 ? 138.652 152.902 163.722 1.00 77.44  ? 428 ARG A N   1 
ATOM   2581  C CA  . ARG A 1 375 ? 137.378 153.486 163.300 1.00 78.63  ? 428 ARG A CA  1 
ATOM   2582  C C   . ARG A 1 375 ? 137.560 154.746 162.463 1.00 80.61  ? 428 ARG A C   1 
ATOM   2583  O O   . ARG A 1 375 ? 136.706 155.066 161.630 1.00 83.99  ? 428 ARG A O   1 
ATOM   2584  C CB  . ARG A 1 375 ? 136.516 153.822 164.519 1.00 82.27  ? 428 ARG A CB  1 
ATOM   2585  C CG  . ARG A 1 375 ? 135.963 152.638 165.291 1.00 89.19  ? 428 ARG A CG  1 
ATOM   2586  C CD  . ARG A 1 375 ? 135.186 153.130 166.503 1.00 87.32  ? 428 ARG A CD  1 
ATOM   2587  N NE  . ARG A 1 375 ? 134.798 152.055 167.408 1.00 93.88  ? 428 ARG A NE  1 
ATOM   2588  C CZ  . ARG A 1 375 ? 134.197 152.244 168.575 1.00 98.90  ? 428 ARG A CZ  1 
ATOM   2589  N NH1 . ARG A 1 375 ? 133.901 153.458 169.010 1.00 103.03 ? 428 ARG A NH1 1 
ATOM   2590  N NH2 . ARG A 1 375 ? 133.887 151.190 169.324 1.00 99.87  ? 428 ARG A NH2 1 
ATOM   2591  N N   . ILE A 1 376 ? 138.654 155.473 162.671 1.00 75.60  ? 429 ILE A N   1 
ATOM   2592  C CA  . ILE A 1 376 ? 138.928 156.703 161.946 1.00 70.54  ? 429 ILE A CA  1 
ATOM   2593  C C   . ILE A 1 376 ? 140.064 156.527 160.946 1.00 67.87  ? 429 ILE A C   1 
ATOM   2594  O O   . ILE A 1 376 ? 140.024 157.096 159.853 1.00 70.94  ? 429 ILE A O   1 
ATOM   2595  C CB  . ILE A 1 376 ? 139.227 157.856 162.930 1.00 69.85  ? 429 ILE A CB  1 
ATOM   2596  C CG1 . ILE A 1 376 ? 137.982 158.186 163.756 1.00 73.41  ? 429 ILE A CG1 1 
ATOM   2597  C CG2 . ILE A 1 376 ? 139.718 159.089 162.193 1.00 76.01  ? 429 ILE A CG2 1 
ATOM   2598  C CD1 . ILE A 1 376 ? 138.166 159.351 164.708 1.00 78.87  ? 429 ILE A CD1 1 
ATOM   2599  N N   . VAL A 1 377 ? 141.076 155.730 161.292 1.00 66.16  ? 430 VAL A N   1 
ATOM   2600  C CA  . VAL A 1 377 ? 142.231 155.571 160.416 1.00 66.34  ? 430 VAL A CA  1 
ATOM   2601  C C   . VAL A 1 377 ? 141.835 154.888 159.114 1.00 68.13  ? 430 VAL A C   1 
ATOM   2602  O O   . VAL A 1 377 ? 142.262 155.304 158.030 1.00 66.88  ? 430 VAL A O   1 
ATOM   2603  C CB  . VAL A 1 377 ? 143.352 154.805 161.141 1.00 65.33  ? 430 VAL A CB  1 
ATOM   2604  C CG1 . VAL A 1 377 ? 144.439 154.404 160.160 1.00 59.58  ? 430 VAL A CG1 1 
ATOM   2605  C CG2 . VAL A 1 377 ? 143.937 155.659 162.247 1.00 75.99  ? 430 VAL A CG2 1 
ATOM   2606  N N   . PHE A 1 378 ? 141.018 153.830 159.189 1.00 68.02  ? 431 PHE A N   1 
ATOM   2607  C CA  . PHE A 1 378 ? 140.669 153.115 157.961 1.00 67.46  ? 431 PHE A CA  1 
ATOM   2608  C C   . PHE A 1 378 ? 139.869 153.974 156.989 1.00 68.75  ? 431 PHE A C   1 
ATOM   2609  O O   . PHE A 1 378 ? 140.234 154.021 155.800 1.00 68.80  ? 431 PHE A O   1 
ATOM   2610  C CB  . PHE A 1 378 ? 139.948 151.808 158.302 1.00 66.62  ? 431 PHE A CB  1 
ATOM   2611  C CG  . PHE A 1 378 ? 140.870 150.635 158.463 1.00 63.33  ? 431 PHE A CG  1 
ATOM   2612  C CD1 . PHE A 1 378 ? 141.273 149.899 157.362 1.00 59.76  ? 431 PHE A CD1 1 
ATOM   2613  C CD2 . PHE A 1 378 ? 141.337 150.271 159.713 1.00 65.01  ? 431 PHE A CD2 1 
ATOM   2614  C CE1 . PHE A 1 378 ? 142.121 148.822 157.505 1.00 60.24  ? 431 PHE A CE1 1 
ATOM   2615  C CE2 . PHE A 1 378 ? 142.186 149.194 159.863 1.00 62.78  ? 431 PHE A CE2 1 
ATOM   2616  C CZ  . PHE A 1 378 ? 142.579 148.468 158.757 1.00 58.70  ? 431 PHE A CZ  1 
ATOM   2617  N N   . PRO A 1 379 ? 138.787 154.658 157.392 1.00 67.91  ? 432 PRO A N   1 
ATOM   2618  C CA  . PRO A 1 379 ? 138.065 155.489 156.412 1.00 67.05  ? 432 PRO A CA  1 
ATOM   2619  C C   . PRO A 1 379 ? 138.915 156.588 155.799 1.00 66.30  ? 432 PRO A C   1 
ATOM   2620  O O   . PRO A 1 379 ? 138.813 156.841 154.593 1.00 73.07  ? 432 PRO A O   1 
ATOM   2621  C CB  . PRO A 1 379 ? 136.900 156.061 157.232 1.00 65.25  ? 432 PRO A CB  1 
ATOM   2622  C CG  . PRO A 1 379 ? 136.720 155.103 158.349 1.00 66.86  ? 432 PRO A CG  1 
ATOM   2623  C CD  . PRO A 1 379 ? 138.100 154.649 158.695 1.00 67.03  ? 432 PRO A CD  1 
ATOM   2624  N N   . PHE A 1 380 ? 139.768 157.238 156.593 1.00 62.21  ? 433 PHE A N   1 
ATOM   2625  C CA  . PHE A 1 380 ? 140.605 158.309 156.062 1.00 64.24  ? 433 PHE A CA  1 
ATOM   2626  C C   . PHE A 1 380 ? 141.619 157.774 155.058 1.00 66.55  ? 433 PHE A C   1 
ATOM   2627  O O   . PHE A 1 380 ? 141.836 158.378 154.000 1.00 69.97  ? 433 PHE A O   1 
ATOM   2628  C CB  . PHE A 1 380 ? 141.308 159.035 157.209 1.00 67.95  ? 433 PHE A CB  1 
ATOM   2629  C CG  . PHE A 1 380 ? 142.211 160.147 156.762 1.00 71.32  ? 433 PHE A CG  1 
ATOM   2630  C CD1 . PHE A 1 380 ? 141.687 161.368 156.374 1.00 79.64  ? 433 PHE A CD1 1 
ATOM   2631  C CD2 . PHE A 1 380 ? 143.584 159.975 156.740 1.00 68.15  ? 433 PHE A CD2 1 
ATOM   2632  C CE1 . PHE A 1 380 ? 142.515 162.395 155.965 1.00 81.20  ? 433 PHE A CE1 1 
ATOM   2633  C CE2 . PHE A 1 380 ? 144.417 160.997 156.333 1.00 76.22  ? 433 PHE A CE2 1 
ATOM   2634  C CZ  . PHE A 1 380 ? 143.882 162.209 155.945 1.00 80.86  ? 433 PHE A CZ  1 
ATOM   2635  N N   . THR A 1 381 ? 142.250 156.641 155.372 1.00 64.60  ? 434 THR A N   1 
ATOM   2636  C CA  . THR A 1 381 ? 143.212 156.046 154.451 1.00 63.74  ? 434 THR A CA  1 
ATOM   2637  C C   . THR A 1 381 ? 142.537 155.596 153.162 1.00 63.11  ? 434 THR A C   1 
ATOM   2638  O O   . THR A 1 381 ? 143.091 155.770 152.070 1.00 61.35  ? 434 THR A O   1 
ATOM   2639  C CB  . THR A 1 381 ? 143.921 154.871 155.121 1.00 61.76  ? 434 THR A CB  1 
ATOM   2640  O OG1 . THR A 1 381 ? 144.374 155.266 156.421 1.00 66.79  ? 434 THR A OG1 1 
ATOM   2641  C CG2 . THR A 1 381 ? 145.115 154.430 154.293 1.00 58.65  ? 434 THR A CG2 1 
ATOM   2642  N N   . PHE A 1 382 ? 141.341 155.014 153.265 1.00 62.71  ? 435 PHE A N   1 
ATOM   2643  C CA  . PHE A 1 382 ? 140.616 154.609 152.065 1.00 62.80  ? 435 PHE A CA  1 
ATOM   2644  C C   . PHE A 1 382 ? 140.216 155.817 151.228 1.00 65.18  ? 435 PHE A C   1 
ATOM   2645  O O   . PHE A 1 382 ? 140.256 155.767 149.993 1.00 68.79  ? 435 PHE A O   1 
ATOM   2646  C CB  . PHE A 1 382 ? 139.391 153.787 152.450 1.00 62.58  ? 435 PHE A CB  1 
ATOM   2647  C CG  . PHE A 1 382 ? 138.670 153.181 151.282 1.00 65.32  ? 435 PHE A CG  1 
ATOM   2648  C CD1 . PHE A 1 382 ? 139.269 152.197 150.516 1.00 62.95  ? 435 PHE A CD1 1 
ATOM   2649  C CD2 . PHE A 1 382 ? 137.383 153.578 150.964 1.00 65.75  ? 435 PHE A CD2 1 
ATOM   2650  C CE1 . PHE A 1 382 ? 138.605 151.632 149.449 1.00 63.71  ? 435 PHE A CE1 1 
ATOM   2651  C CE2 . PHE A 1 382 ? 136.712 153.013 149.900 1.00 61.23  ? 435 PHE A CE2 1 
ATOM   2652  C CZ  . PHE A 1 382 ? 137.325 152.041 149.141 1.00 59.63  ? 435 PHE A CZ  1 
ATOM   2653  N N   . SER A 1 383 ? 139.816 156.909 151.883 1.00 61.73  ? 436 SER A N   1 
ATOM   2654  C CA  . SER A 1 383 ? 139.497 158.134 151.157 1.00 58.73  ? 436 SER A CA  1 
ATOM   2655  C C   . SER A 1 383 ? 140.722 158.680 150.436 1.00 60.80  ? 436 SER A C   1 
ATOM   2656  O O   . SER A 1 383 ? 140.625 159.137 149.294 1.00 67.54  ? 436 SER A O   1 
ATOM   2657  C CB  . SER A 1 383 ? 138.929 159.179 152.115 1.00 64.40  ? 436 SER A CB  1 
ATOM   2658  O OG  . SER A 1 383 ? 137.696 158.749 152.661 1.00 73.64  ? 436 SER A OG  1 
ATOM   2659  N N   . LEU A 1 384 ? 141.884 158.643 151.091 1.00 59.69  ? 437 LEU A N   1 
ATOM   2660  C CA  . LEU A 1 384 ? 143.116 159.079 150.438 1.00 61.56  ? 437 LEU A CA  1 
ATOM   2661  C C   . LEU A 1 384 ? 143.455 158.192 149.245 1.00 61.24  ? 437 LEU A C   1 
ATOM   2662  O O   . LEU A 1 384 ? 143.896 158.683 148.196 1.00 60.48  ? 437 LEU A O   1 
ATOM   2663  C CB  . LEU A 1 384 ? 144.264 159.085 151.448 1.00 62.42  ? 437 LEU A CB  1 
ATOM   2664  C CG  . LEU A 1 384 ? 145.671 159.336 150.907 1.00 62.96  ? 437 LEU A CG  1 
ATOM   2665  C CD1 . LEU A 1 384 ? 145.769 160.721 150.292 1.00 68.08  ? 437 LEU A CD1 1 
ATOM   2666  C CD2 . LEU A 1 384 ? 146.706 159.157 152.006 1.00 58.38  ? 437 LEU A CD2 1 
ATOM   2667  N N   . PHE A 1 385 ? 143.266 156.879 149.394 1.00 59.72  ? 438 PHE A N   1 
ATOM   2668  C CA  . PHE A 1 385 ? 143.516 155.959 148.290 1.00 57.54  ? 438 PHE A CA  1 
ATOM   2669  C C   . PHE A 1 385 ? 142.591 156.244 147.114 1.00 56.90  ? 438 PHE A C   1 
ATOM   2670  O O   . PHE A 1 385 ? 143.030 156.260 145.959 1.00 61.80  ? 438 PHE A O   1 
ATOM   2671  C CB  . PHE A 1 385 ? 143.352 154.516 148.769 1.00 59.52  ? 438 PHE A CB  1 
ATOM   2672  C CG  . PHE A 1 385 ? 143.096 153.535 147.663 1.00 57.75  ? 438 PHE A CG  1 
ATOM   2673  C CD1 . PHE A 1 385 ? 144.130 153.099 146.853 1.00 52.75  ? 438 PHE A CD1 1 
ATOM   2674  C CD2 . PHE A 1 385 ? 141.822 153.042 147.439 1.00 57.85  ? 438 PHE A CD2 1 
ATOM   2675  C CE1 . PHE A 1 385 ? 143.896 152.197 145.837 1.00 49.69  ? 438 PHE A CE1 1 
ATOM   2676  C CE2 . PHE A 1 385 ? 141.583 152.140 146.426 1.00 56.30  ? 438 PHE A CE2 1 
ATOM   2677  C CZ  . PHE A 1 385 ? 142.621 151.716 145.623 1.00 52.27  ? 438 PHE A CZ  1 
ATOM   2678  N N   . ASN A 1 386 ? 141.305 156.473 147.387 1.00 55.82  ? 439 ASN A N   1 
ATOM   2679  C CA  . ASN A 1 386 ? 140.378 156.820 146.315 1.00 57.22  ? 439 ASN A CA  1 
ATOM   2680  C C   . ASN A 1 386 ? 140.753 158.145 145.670 1.00 60.03  ? 439 ASN A C   1 
ATOM   2681  O O   . ASN A 1 386 ? 140.650 158.300 144.449 1.00 59.15  ? 439 ASN A O   1 
ATOM   2682  C CB  . ASN A 1 386 ? 138.947 156.872 146.846 1.00 56.48  ? 439 ASN A CB  1 
ATOM   2683  C CG  . ASN A 1 386 ? 138.334 155.500 146.989 1.00 63.17  ? 439 ASN A CG  1 
ATOM   2684  O OD1 . ASN A 1 386 ? 137.728 154.978 146.054 1.00 61.83  ? 439 ASN A OD1 1 
ATOM   2685  N ND2 . ASN A 1 386 ? 138.488 154.905 148.163 1.00 63.08  ? 439 ASN A ND2 1 
ATOM   2686  N N   . LEU A 1 387 ? 141.195 159.113 146.475 1.00 61.53  ? 440 LEU A N   1 
ATOM   2687  C CA  . LEU A 1 387 ? 141.607 160.402 145.933 1.00 60.69  ? 440 LEU A CA  1 
ATOM   2688  C C   . LEU A 1 387 ? 142.761 160.238 144.954 1.00 62.23  ? 440 LEU A C   1 
ATOM   2689  O O   . LEU A 1 387 ? 142.697 160.718 143.817 1.00 67.67  ? 440 LEU A O   1 
ATOM   2690  C CB  . LEU A 1 387 ? 141.997 161.345 147.071 1.00 60.26  ? 440 LEU A CB  1 
ATOM   2691  C CG  . LEU A 1 387 ? 142.626 162.679 146.670 1.00 67.15  ? 440 LEU A CG  1 
ATOM   2692  C CD1 . LEU A 1 387 ? 141.612 163.555 145.957 1.00 67.66  ? 440 LEU A CD1 1 
ATOM   2693  C CD2 . LEU A 1 387 ? 143.196 163.390 147.887 1.00 69.50  ? 440 LEU A CD2 1 
ATOM   2694  N N   . VAL A 1 388 ? 143.822 159.547 145.373 1.00 57.58  ? 441 VAL A N   1 
ATOM   2695  C CA  . VAL A 1 388 ? 144.976 159.396 144.492 1.00 60.25  ? 441 VAL A CA  1 
ATOM   2696  C C   . VAL A 1 388 ? 144.614 158.557 143.268 1.00 61.47  ? 441 VAL A C   1 
ATOM   2697  O O   . VAL A 1 388 ? 145.037 158.863 142.146 1.00 62.74  ? 441 VAL A O   1 
ATOM   2698  C CB  . VAL A 1 388 ? 146.185 158.823 145.258 1.00 59.10  ? 441 VAL A CB  1 
ATOM   2699  C CG1 . VAL A 1 388 ? 145.866 157.478 145.877 1.00 59.36  ? 441 VAL A CG1 1 
ATOM   2700  C CG2 . VAL A 1 388 ? 147.392 158.715 144.341 1.00 55.96  ? 441 VAL A CG2 1 
ATOM   2701  N N   . TYR A 1 389 ? 143.800 157.512 143.450 1.00 58.75  ? 442 TYR A N   1 
ATOM   2702  C CA  . TYR A 1 389 ? 143.417 156.665 142.325 1.00 55.57  ? 442 TYR A CA  1 
ATOM   2703  C C   . TYR A 1 389 ? 142.627 157.450 141.286 1.00 58.65  ? 442 TYR A C   1 
ATOM   2704  O O   . TYR A 1 389 ? 142.926 157.389 140.088 1.00 63.46  ? 442 TYR A O   1 
ATOM   2705  C CB  . TYR A 1 389 ? 142.612 155.466 142.829 1.00 52.64  ? 442 TYR A CB  1 
ATOM   2706  C CG  . TYR A 1 389 ? 141.950 154.647 141.743 1.00 53.48  ? 442 TYR A CG  1 
ATOM   2707  C CD1 . TYR A 1 389 ? 142.634 153.628 141.098 1.00 56.70  ? 442 TYR A CD1 1 
ATOM   2708  C CD2 . TYR A 1 389 ? 140.632 154.883 141.377 1.00 54.37  ? 442 TYR A CD2 1 
ATOM   2709  C CE1 . TYR A 1 389 ? 142.027 152.874 140.111 1.00 57.07  ? 442 TYR A CE1 1 
ATOM   2710  C CE2 . TYR A 1 389 ? 140.021 154.137 140.394 1.00 57.95  ? 442 TYR A CE2 1 
ATOM   2711  C CZ  . TYR A 1 389 ? 140.720 153.134 139.765 1.00 56.38  ? 442 TYR A CZ  1 
ATOM   2712  O OH  . TYR A 1 389 ? 140.106 152.391 138.784 1.00 53.09  ? 442 TYR A OH  1 
ATOM   2713  N N   . TRP A 1 390 ? 141.617 158.202 141.724 1.00 57.99  ? 443 TRP A N   1 
ATOM   2714  C CA  . TRP A 1 390 ? 140.760 158.899 140.774 1.00 61.51  ? 443 TRP A CA  1 
ATOM   2715  C C   . TRP A 1 390 ? 141.423 160.139 140.193 1.00 61.99  ? 443 TRP A C   1 
ATOM   2716  O O   . TRP A 1 390 ? 141.082 160.544 139.078 1.00 65.64  ? 443 TRP A O   1 
ATOM   2717  C CB  . TRP A 1 390 ? 139.429 159.260 141.431 1.00 63.23  ? 443 TRP A CB  1 
ATOM   2718  C CG  . TRP A 1 390 ? 138.545 158.071 141.623 1.00 65.59  ? 443 TRP A CG  1 
ATOM   2719  C CD1 . TRP A 1 390 ? 138.257 157.445 142.798 1.00 64.91  ? 443 TRP A CD1 1 
ATOM   2720  C CD2 . TRP A 1 390 ? 137.849 157.349 140.602 1.00 59.99  ? 443 TRP A CD2 1 
ATOM   2721  N NE1 . TRP A 1 390 ? 137.416 156.383 142.575 1.00 65.50  ? 443 TRP A NE1 1 
ATOM   2722  C CE2 . TRP A 1 390 ? 137.151 156.302 141.234 1.00 59.60  ? 443 TRP A CE2 1 
ATOM   2723  C CE3 . TRP A 1 390 ? 137.744 157.488 139.216 1.00 52.99  ? 443 TRP A CE3 1 
ATOM   2724  C CZ2 . TRP A 1 390 ? 136.359 155.401 140.528 1.00 53.37  ? 443 TRP A CZ2 1 
ATOM   2725  C CZ3 . TRP A 1 390 ? 136.960 156.594 138.518 1.00 54.47  ? 443 TRP A CZ3 1 
ATOM   2726  C CH2 . TRP A 1 390 ? 136.277 155.564 139.174 1.00 54.73  ? 443 TRP A CH2 1 
ATOM   2727  N N   . LEU A 1 391 ? 142.357 160.762 140.916 1.00 60.65  ? 444 LEU A N   1 
ATOM   2728  C CA  . LEU A 1 391 ? 143.113 161.851 140.310 1.00 63.02  ? 444 LEU A CA  1 
ATOM   2729  C C   . LEU A 1 391 ? 144.123 161.327 139.299 1.00 64.72  ? 444 LEU A C   1 
ATOM   2730  O O   . LEU A 1 391 ? 144.409 162.004 138.305 1.00 66.46  ? 444 LEU A O   1 
ATOM   2731  C CB  . LEU A 1 391 ? 143.815 162.682 141.384 1.00 65.71  ? 444 LEU A CB  1 
ATOM   2732  C CG  . LEU A 1 391 ? 142.930 163.516 142.312 1.00 66.98  ? 444 LEU A CG  1 
ATOM   2733  C CD1 . LEU A 1 391 ? 143.776 164.487 143.122 1.00 62.81  ? 444 LEU A CD1 1 
ATOM   2734  C CD2 . LEU A 1 391 ? 141.857 164.257 141.530 1.00 64.16  ? 444 LEU A CD2 1 
ATOM   2735  N N   . TYR A 1 392 ? 144.673 160.133 139.533 1.00 61.92  ? 445 TYR A N   1 
ATOM   2736  C CA  . TYR A 1 392 ? 145.654 159.577 138.608 1.00 62.52  ? 445 TYR A CA  1 
ATOM   2737  C C   . TYR A 1 392 ? 145.013 159.184 137.281 1.00 68.57  ? 445 TYR A C   1 
ATOM   2738  O O   . TYR A 1 392 ? 145.536 159.509 136.209 1.00 71.05  ? 445 TYR A O   1 
ATOM   2739  C CB  . TYR A 1 392 ? 146.348 158.376 139.249 1.00 63.94  ? 445 TYR A CB  1 
ATOM   2740  C CG  . TYR A 1 392 ? 147.289 157.637 138.325 1.00 68.57  ? 445 TYR A CG  1 
ATOM   2741  C CD1 . TYR A 1 392 ? 148.593 158.072 138.137 1.00 74.92  ? 445 TYR A CD1 1 
ATOM   2742  C CD2 . TYR A 1 392 ? 146.875 156.498 137.648 1.00 68.78  ? 445 TYR A CD2 1 
ATOM   2743  C CE1 . TYR A 1 392 ? 149.456 157.398 137.296 1.00 79.86  ? 445 TYR A CE1 1 
ATOM   2744  C CE2 . TYR A 1 392 ? 147.731 155.818 136.806 1.00 73.90  ? 445 TYR A CE2 1 
ATOM   2745  C CZ  . TYR A 1 392 ? 149.019 156.272 136.633 1.00 80.10  ? 445 TYR A CZ  1 
ATOM   2746  O OH  . TYR A 1 392 ? 149.874 155.595 135.795 1.00 86.41  ? 445 TYR A OH  1 
ATOM   2747  N N   . TYR A 1 393 ? 143.876 158.493 137.330 1.00 66.66  ? 446 TYR A N   1 
ATOM   2748  C CA  . TYR A 1 393 ? 143.284 157.898 136.138 1.00 61.53  ? 446 TYR A CA  1 
ATOM   2749  C C   . TYR A 1 393 ? 142.275 158.797 135.435 1.00 61.60  ? 446 TYR A C   1 
ATOM   2750  O O   . TYR A 1 393 ? 141.733 158.396 134.401 1.00 64.89  ? 446 TYR A O   1 
ATOM   2751  C CB  . TYR A 1 393 ? 142.617 156.565 136.486 1.00 56.33  ? 446 TYR A CB  1 
ATOM   2752  C CG  . TYR A 1 393 ? 143.576 155.399 136.511 1.00 57.05  ? 446 TYR A CG  1 
ATOM   2753  C CD1 . TYR A 1 393 ? 144.186 154.957 135.348 1.00 59.03  ? 446 TYR A CD1 1 
ATOM   2754  C CD2 . TYR A 1 393 ? 143.864 154.738 137.694 1.00 57.86  ? 446 TYR A CD2 1 
ATOM   2755  C CE1 . TYR A 1 393 ? 145.062 153.893 135.362 1.00 59.74  ? 446 TYR A CE1 1 
ATOM   2756  C CE2 . TYR A 1 393 ? 144.739 153.671 137.716 1.00 60.51  ? 446 TYR A CE2 1 
ATOM   2757  C CZ  . TYR A 1 393 ? 145.335 153.253 136.548 1.00 60.97  ? 446 TYR A CZ  1 
ATOM   2758  O OH  . TYR A 1 393 ? 146.207 152.190 136.563 1.00 56.98  ? 446 TYR A OH  1 
ATOM   2759  N N   . VAL A 1 394 ? 141.999 159.986 135.960 1.00 63.90  ? 447 VAL A N   1 
ATOM   2760  C CA  . VAL A 1 394 ? 141.089 160.902 135.283 1.00 65.19  ? 447 VAL A CA  1 
ATOM   2761  C C   . VAL A 1 394 ? 141.806 162.207 134.961 1.00 67.20  ? 447 VAL A C   1 
ATOM   2762  O O   . VAL A 1 394 ? 142.944 162.201 134.491 1.00 67.00  ? 447 VAL A O   1 
ATOM   2763  C CB  . VAL A 1 394 ? 139.827 161.168 136.119 1.00 62.41  ? 447 VAL A CB  1 
ATOM   2764  C CG1 . VAL A 1 394 ? 138.876 162.081 135.363 1.00 65.07  ? 447 VAL A CG1 1 
ATOM   2765  C CG2 . VAL A 1 394 ? 139.141 159.862 136.470 1.00 57.99  ? 447 VAL A CG2 1 
ATOM   2766  N N   . ASN B 1 58  ? 151.803 151.538 68.736  1.00 129.04 ? 4   ASN B N   1 
ATOM   2767  C CA  . ASN B 1 58  ? 153.025 150.912 69.226  1.00 133.37 ? 4   ASN B CA  1 
ATOM   2768  C C   . ASN B 1 58  ? 153.371 151.413 70.624  1.00 141.10 ? 4   ASN B C   1 
ATOM   2769  O O   . ASN B 1 58  ? 153.941 150.680 71.433  1.00 137.43 ? 4   ASN B O   1 
ATOM   2770  C CB  . ASN B 1 58  ? 154.186 151.180 68.266  1.00 135.36 ? 4   ASN B CB  1 
ATOM   2771  C CG  . ASN B 1 58  ? 155.477 150.521 68.713  1.00 138.85 ? 4   ASN B CG  1 
ATOM   2772  O OD1 . ASN B 1 58  ? 155.729 149.354 68.411  1.00 140.61 ? 4   ASN B OD1 1 
ATOM   2773  N ND2 . ASN B 1 58  ? 156.304 151.268 69.435  1.00 137.25 ? 4   ASN B ND2 1 
ATOM   2774  N N   . ASP B 1 59  ? 153.024 152.667 70.900  1.00 147.28 ? 5   ASP B N   1 
ATOM   2775  C CA  . ASP B 1 59  ? 153.302 153.246 72.202  1.00 147.41 ? 5   ASP B CA  1 
ATOM   2776  C C   . ASP B 1 59  ? 152.409 152.613 73.269  1.00 144.40 ? 5   ASP B C   1 
ATOM   2777  O O   . ASP B 1 59  ? 151.280 152.205 72.983  1.00 140.82 ? 5   ASP B O   1 
ATOM   2778  C CB  . ASP B 1 59  ? 153.083 154.756 72.175  1.00 145.81 ? 5   ASP B CB  1 
ATOM   2779  C CG  . ASP B 1 59  ? 153.924 155.449 71.122  1.00 146.85 ? 5   ASP B CG  1 
ATOM   2780  O OD1 . ASP B 1 59  ? 155.052 154.985 70.856  1.00 141.66 ? 5   ASP B OD1 1 
ATOM   2781  O OD2 . ASP B 1 59  ? 153.454 156.459 70.559  1.00 151.66 ? 5   ASP B OD2 1 
ATOM   2782  N N   . PRO B 1 60  ? 152.896 152.517 74.509  1.00 146.34 ? 6   PRO B N   1 
ATOM   2783  C CA  . PRO B 1 60  ? 152.053 151.978 75.589  1.00 144.06 ? 6   PRO B CA  1 
ATOM   2784  C C   . PRO B 1 60  ? 150.790 152.783 75.835  1.00 142.44 ? 6   PRO B C   1 
ATOM   2785  O O   . PRO B 1 60  ? 149.816 152.229 76.360  1.00 141.88 ? 6   PRO B O   1 
ATOM   2786  C CB  . PRO B 1 60  ? 152.983 152.010 76.810  1.00 136.84 ? 6   PRO B CB  1 
ATOM   2787  C CG  . PRO B 1 60  ? 154.360 151.999 76.238  1.00 132.50 ? 6   PRO B CG  1 
ATOM   2788  C CD  . PRO B 1 60  ? 154.273 152.778 74.960  1.00 142.97 ? 6   PRO B CD  1 
ATOM   2789  N N   . GLY B 1 61  ? 150.776 154.072 75.487  1.00 140.01 ? 7   GLY B N   1 
ATOM   2790  C CA  . GLY B 1 61  ? 149.563 154.856 75.636  1.00 138.31 ? 7   GLY B CA  1 
ATOM   2791  C C   . GLY B 1 61  ? 148.416 154.337 74.792  1.00 136.37 ? 7   GLY B C   1 
ATOM   2792  O O   . GLY B 1 61  ? 147.250 154.465 75.175  1.00 132.82 ? 7   GLY B O   1 
ATOM   2793  N N   . ASN B 1 62  ? 148.726 153.755 73.636  1.00 136.26 ? 8   ASN B N   1 
ATOM   2794  C CA  . ASN B 1 62  ? 147.713 153.146 72.781  1.00 131.55 ? 8   ASN B CA  1 
ATOM   2795  C C   . ASN B 1 62  ? 147.145 151.917 73.480  1.00 126.63 ? 8   ASN B C   1 
ATOM   2796  O O   . ASN B 1 62  ? 147.809 150.880 73.566  1.00 124.74 ? 8   ASN B O   1 
ATOM   2797  C CB  . ASN B 1 62  ? 148.326 152.786 71.430  1.00 131.41 ? 8   ASN B CB  1 
ATOM   2798  C CG  . ASN B 1 62  ? 147.302 152.278 70.432  1.00 131.56 ? 8   ASN B CG  1 
ATOM   2799  O OD1 . ASN B 1 62  ? 146.099 152.291 70.692  1.00 131.03 ? 8   ASN B OD1 1 
ATOM   2800  N ND2 . ASN B 1 62  ? 147.781 151.832 69.275  1.00 131.86 ? 8   ASN B ND2 1 
ATOM   2801  N N   . MET B 1 63  ? 145.914 152.032 73.985  1.00 125.12 ? 9   MET B N   1 
ATOM   2802  C CA  . MET B 1 63  ? 145.318 150.932 74.736  1.00 118.67 ? 9   MET B CA  1 
ATOM   2803  C C   . MET B 1 63  ? 144.936 149.769 73.831  1.00 115.07 ? 9   MET B C   1 
ATOM   2804  O O   . MET B 1 63  ? 144.971 148.613 74.266  1.00 112.81 ? 9   MET B O   1 
ATOM   2805  C CB  . MET B 1 63  ? 144.095 151.423 75.509  1.00 112.51 ? 9   MET B CB  1 
ATOM   2806  C CG  . MET B 1 63  ? 144.413 152.442 76.591  1.00 113.67 ? 9   MET B CG  1 
ATOM   2807  S SD  . MET B 1 63  ? 142.968 152.877 77.575  1.00 120.80 ? 9   MET B SD  1 
ATOM   2808  C CE  . MET B 1 63  ? 142.515 151.277 78.237  1.00 95.61  ? 9   MET B CE  1 
ATOM   2809  N N   . SER B 1 64  ? 144.565 150.050 72.581  1.00 116.78 ? 10  SER B N   1 
ATOM   2810  C CA  . SER B 1 64  ? 144.205 148.975 71.662  1.00 112.89 ? 10  SER B CA  1 
ATOM   2811  C C   . SER B 1 64  ? 145.411 148.105 71.328  1.00 113.28 ? 10  SER B C   1 
ATOM   2812  O O   . SER B 1 64  ? 145.281 146.884 71.191  1.00 109.82 ? 10  SER B O   1 
ATOM   2813  C CB  . SER B 1 64  ? 143.585 149.557 70.393  1.00 118.46 ? 10  SER B CB  1 
ATOM   2814  O OG  . SER B 1 64  ? 144.321 150.677 69.939  1.00 127.01 ? 10  SER B OG  1 
ATOM   2815  N N   . PHE B 1 65  ? 146.592 148.713 71.196  1.00 116.46 ? 11  PHE B N   1 
ATOM   2816  C CA  . PHE B 1 65  ? 147.803 147.931 70.962  1.00 111.30 ? 11  PHE B CA  1 
ATOM   2817  C C   . PHE B 1 65  ? 148.112 147.020 72.146  1.00 102.74 ? 11  PHE B C   1 
ATOM   2818  O O   . PHE B 1 65  ? 148.498 145.858 71.966  1.00 97.20  ? 11  PHE B O   1 
ATOM   2819  C CB  . PHE B 1 65  ? 148.976 148.865 70.674  1.00 113.90 ? 11  PHE B CB  1 
ATOM   2820  C CG  . PHE B 1 65  ? 150.309 148.180 70.675  1.00 113.05 ? 11  PHE B CG  1 
ATOM   2821  C CD1 . PHE B 1 65  ? 150.643 147.282 69.676  1.00 115.25 ? 11  PHE B CD1 1 
ATOM   2822  C CD2 . PHE B 1 65  ? 151.233 148.442 71.671  1.00 111.90 ? 11  PHE B CD2 1 
ATOM   2823  C CE1 . PHE B 1 65  ? 151.871 146.653 69.676  1.00 114.49 ? 11  PHE B CE1 1 
ATOM   2824  C CE2 . PHE B 1 65  ? 152.463 147.817 71.675  1.00 111.90 ? 11  PHE B CE2 1 
ATOM   2825  C CZ  . PHE B 1 65  ? 152.782 146.921 70.676  1.00 111.42 ? 11  PHE B CZ  1 
ATOM   2826  N N   . VAL B 1 66  ? 147.937 147.528 73.368  1.00 105.34 ? 12  VAL B N   1 
ATOM   2827  C CA  . VAL B 1 66  ? 148.176 146.709 74.551  1.00 96.83  ? 12  VAL B CA  1 
ATOM   2828  C C   . VAL B 1 66  ? 147.152 145.584 74.637  1.00 93.82  ? 12  VAL B C   1 
ATOM   2829  O O   . VAL B 1 66  ? 147.483 144.454 75.017  1.00 96.63  ? 12  VAL B O   1 
ATOM   2830  C CB  . VAL B 1 66  ? 148.169 147.584 75.816  1.00 96.92  ? 12  VAL B CB  1 
ATOM   2831  C CG1 . VAL B 1 66  ? 148.464 146.742 77.047  1.00 95.45  ? 12  VAL B CG1 1 
ATOM   2832  C CG2 . VAL B 1 66  ? 149.181 148.712 75.684  1.00 102.30 ? 12  VAL B CG2 1 
ATOM   2833  N N   . LYS B 1 67  ? 145.895 145.870 74.293  1.00 94.23  ? 13  LYS B N   1 
ATOM   2834  C CA  . LYS B 1 67  ? 144.879 144.822 74.283  1.00 93.98  ? 13  LYS B CA  1 
ATOM   2835  C C   . LYS B 1 67  ? 145.199 143.755 73.244  1.00 94.07  ? 13  LYS B C   1 
ATOM   2836  O O   . LYS B 1 67  ? 145.004 142.559 73.491  1.00 90.95  ? 13  LYS B O   1 
ATOM   2837  C CB  . LYS B 1 67  ? 143.498 145.418 74.022  1.00 92.75  ? 13  LYS B CB  1 
ATOM   2838  C CG  . LYS B 1 67  ? 142.393 144.377 74.017  1.00 87.72  ? 13  LYS B CG  1 
ATOM   2839  C CD  . LYS B 1 67  ? 141.132 144.895 73.358  1.00 89.99  ? 13  LYS B CD  1 
ATOM   2840  C CE  . LYS B 1 67  ? 140.089 143.797 73.247  1.00 90.22  ? 13  LYS B CE  1 
ATOM   2841  N NZ  . LYS B 1 67  ? 138.874 144.257 72.524  1.00 95.95  ? 13  LYS B NZ  1 
ATOM   2842  N N   . GLU B 1 68  ? 145.680 144.169 72.070  1.00 98.62  ? 14  GLU B N   1 
ATOM   2843  C CA  . GLU B 1 68  ? 146.102 143.203 71.062  1.00 95.84  ? 14  GLU B CA  1 
ATOM   2844  C C   . GLU B 1 68  ? 147.243 142.340 71.579  1.00 93.14  ? 14  GLU B C   1 
ATOM   2845  O O   . GLU B 1 68  ? 147.257 141.122 71.365  1.00 97.29  ? 14  GLU B O   1 
ATOM   2846  C CB  . GLU B 1 68  ? 146.524 143.922 69.780  1.00 101.77 ? 14  GLU B CB  1 
ATOM   2847  C CG  . GLU B 1 68  ? 145.472 143.932 68.687  1.00 108.02 ? 14  GLU B CG  1 
ATOM   2848  C CD  . GLU B 1 68  ? 146.042 144.350 67.346  1.00 117.49 ? 14  GLU B CD  1 
ATOM   2849  O OE1 . GLU B 1 68  ? 147.274 144.543 67.258  1.00 120.23 ? 14  GLU B OE1 1 
ATOM   2850  O OE2 . GLU B 1 68  ? 145.262 144.484 66.379  1.00 117.13 ? 14  GLU B OE2 1 
ATOM   2851  N N   . THR B 1 69  ? 148.210 142.955 72.261  1.00 87.86  ? 15  THR B N   1 
ATOM   2852  C CA  . THR B 1 69  ? 149.321 142.188 72.814  1.00 85.73  ? 15  THR B CA  1 
ATOM   2853  C C   . THR B 1 69  ? 148.838 141.181 73.853  1.00 84.86  ? 15  THR B C   1 
ATOM   2854  O O   . THR B 1 69  ? 149.284 140.028 73.866  1.00 88.74  ? 15  THR B O   1 
ATOM   2855  C CB  . THR B 1 69  ? 150.355 143.135 73.422  1.00 88.09  ? 15  THR B CB  1 
ATOM   2856  O OG1 . THR B 1 69  ? 150.784 144.072 72.429  1.00 96.42  ? 15  THR B OG1 1 
ATOM   2857  C CG2 . THR B 1 69  ? 151.556 142.356 73.922  1.00 79.71  ? 15  THR B CG2 1 
ATOM   2858  N N   . VAL B 1 70  ? 147.914 141.594 74.722  1.00 83.44  ? 16  VAL B N   1 
ATOM   2859  C CA  . VAL B 1 70  ? 147.403 140.687 75.748  1.00 82.07  ? 16  VAL B CA  1 
ATOM   2860  C C   . VAL B 1 70  ? 146.617 139.542 75.116  1.00 81.03  ? 16  VAL B C   1 
ATOM   2861  O O   . VAL B 1 70  ? 146.741 138.382 75.531  1.00 78.82  ? 16  VAL B O   1 
ATOM   2862  C CB  . VAL B 1 70  ? 146.558 141.459 76.777  1.00 79.14  ? 16  VAL B CB  1 
ATOM   2863  C CG1 . VAL B 1 70  ? 145.931 140.499 77.770  1.00 73.89  ? 16  VAL B CG1 1 
ATOM   2864  C CG2 . VAL B 1 70  ? 147.419 142.476 77.506  1.00 71.17  ? 16  VAL B CG2 1 
ATOM   2865  N N   . ASP B 1 71  ? 145.789 139.845 74.112  1.00 82.03  ? 17  ASP B N   1 
ATOM   2866  C CA  . ASP B 1 71  ? 145.038 138.795 73.431  1.00 83.28  ? 17  ASP B CA  1 
ATOM   2867  C C   . ASP B 1 71  ? 145.970 137.824 72.718  1.00 86.10  ? 17  ASP B C   1 
ATOM   2868  O O   . ASP B 1 71  ? 145.715 136.614 72.689  1.00 88.72  ? 17  ASP B O   1 
ATOM   2869  C CB  . ASP B 1 71  ? 144.044 139.410 72.446  1.00 88.39  ? 17  ASP B CB  1 
ATOM   2870  C CG  . ASP B 1 71  ? 142.665 139.592 73.049  1.00 97.30  ? 17  ASP B CG  1 
ATOM   2871  O OD1 . ASP B 1 71  ? 142.176 138.651 73.709  1.00 98.90  ? 17  ASP B OD1 1 
ATOM   2872  O OD2 . ASP B 1 71  ? 142.071 140.674 72.866  1.00 102.63 ? 17  ASP B OD2 1 
ATOM   2873  N N   . LYS B 1 72  ? 147.053 138.336 72.129  1.00 83.42  ? 18  LYS B N   1 
ATOM   2874  C CA  . LYS B 1 72  ? 148.055 137.459 71.534  1.00 77.46  ? 18  LYS B CA  1 
ATOM   2875  C C   . LYS B 1 72  ? 148.704 136.573 72.590  1.00 82.36  ? 18  LYS B C   1 
ATOM   2876  O O   . LYS B 1 72  ? 148.955 135.387 72.348  1.00 81.41  ? 18  LYS B O   1 
ATOM   2877  C CB  . LYS B 1 72  ? 149.110 138.293 70.808  1.00 77.24  ? 18  LYS B CB  1 
ATOM   2878  C CG  . LYS B 1 72  ? 150.256 137.486 70.227  1.00 88.83  ? 18  LYS B CG  1 
ATOM   2879  C CD  . LYS B 1 72  ? 151.266 138.390 69.542  1.00 91.26  ? 18  LYS B CD  1 
ATOM   2880  C CE  . LYS B 1 72  ? 152.437 137.594 68.992  1.00 87.74  ? 18  LYS B CE  1 
ATOM   2881  N NZ  . LYS B 1 72  ? 153.419 138.468 68.292  1.00 89.07  ? 18  LYS B NZ  1 
ATOM   2882  N N   . LEU B 1 73  ? 148.985 137.137 73.768  1.00 86.30  ? 19  LEU B N   1 
ATOM   2883  C CA  . LEU B 1 73  ? 149.565 136.347 74.850  1.00 76.74  ? 19  LEU B CA  1 
ATOM   2884  C C   . LEU B 1 73  ? 148.624 135.233 75.290  1.00 78.36  ? 19  LEU B C   1 
ATOM   2885  O O   . LEU B 1 73  ? 149.061 134.103 75.537  1.00 80.03  ? 19  LEU B O   1 
ATOM   2886  C CB  . LEU B 1 73  ? 149.911 137.247 76.035  1.00 71.24  ? 19  LEU B CB  1 
ATOM   2887  C CG  . LEU B 1 73  ? 151.107 138.181 75.865  1.00 73.57  ? 19  LEU B CG  1 
ATOM   2888  C CD1 . LEU B 1 73  ? 151.329 138.997 77.127  1.00 67.63  ? 19  LEU B CD1 1 
ATOM   2889  C CD2 . LEU B 1 73  ? 152.347 137.381 75.519  1.00 66.92  ? 19  LEU B CD2 1 
ATOM   2890  N N   . LEU B 1 74  ? 147.328 135.532 75.396  1.00 78.97  ? 20  LEU B N   1 
ATOM   2891  C CA  . LEU B 1 74  ? 146.333 134.543 75.792  1.00 75.11  ? 20  LEU B CA  1 
ATOM   2892  C C   . LEU B 1 74  ? 145.663 133.872 74.600  1.00 78.86  ? 20  LEU B C   1 
ATOM   2893  O O   . LEU B 1 74  ? 144.528 133.393 74.721  1.00 76.40  ? 20  LEU B O   1 
ATOM   2894  C CB  . LEU B 1 74  ? 145.282 135.185 76.699  1.00 72.57  ? 20  LEU B CB  1 
ATOM   2895  C CG  . LEU B 1 74  ? 145.777 135.681 78.058  1.00 74.73  ? 20  LEU B CG  1 
ATOM   2896  C CD1 . LEU B 1 74  ? 144.606 136.094 78.933  1.00 74.37  ? 20  LEU B CD1 1 
ATOM   2897  C CD2 . LEU B 1 74  ? 146.609 134.612 78.742  1.00 69.88  ? 20  LEU B CD2 1 
ATOM   2898  N N   . LYS B 1 75  ? 146.335 133.821 73.453  1.00 88.51  ? 21  LYS B N   1 
ATOM   2899  C CA  . LYS B 1 75  ? 145.794 133.181 72.259  1.00 87.97  ? 21  LYS B CA  1 
ATOM   2900  C C   . LYS B 1 75  ? 146.273 131.735 72.229  1.00 86.47  ? 21  LYS B C   1 
ATOM   2901  O O   . LYS B 1 75  ? 147.464 131.472 72.035  1.00 87.81  ? 21  LYS B O   1 
ATOM   2902  C CB  . LYS B 1 75  ? 146.222 133.933 71.002  1.00 90.43  ? 21  LYS B CB  1 
ATOM   2903  C CG  . LYS B 1 75  ? 145.502 133.498 69.740  1.00 86.89  ? 21  LYS B CG  1 
ATOM   2904  C CD  . LYS B 1 75  ? 145.788 134.455 68.596  1.00 94.10  ? 21  LYS B CD  1 
ATOM   2905  C CE  . LYS B 1 75  ? 144.948 134.125 67.374  1.00 103.16 ? 21  LYS B CE  1 
ATOM   2906  N NZ  . LYS B 1 75  ? 145.117 135.135 66.292  1.00 97.97  ? 21  LYS B NZ  1 
ATOM   2907  N N   . GLY B 1 76  ? 145.347 130.800 72.422  1.00 87.31  ? 22  GLY B N   1 
ATOM   2908  C CA  . GLY B 1 76  ? 145.707 129.400 72.494  1.00 85.07  ? 22  GLY B CA  1 
ATOM   2909  C C   . GLY B 1 76  ? 146.345 128.973 73.794  1.00 85.51  ? 22  GLY B C   1 
ATOM   2910  O O   . GLY B 1 76  ? 146.872 127.860 73.873  1.00 83.70  ? 22  GLY B O   1 
ATOM   2911  N N   . TYR B 1 77  ? 146.313 129.823 74.818  1.00 83.86  ? 23  TYR B N   1 
ATOM   2912  C CA  . TYR B 1 77  ? 146.926 129.490 76.096  1.00 73.85  ? 23  TYR B CA  1 
ATOM   2913  C C   . TYR B 1 77  ? 146.138 128.383 76.784  1.00 73.05  ? 23  TYR B C   1 
ATOM   2914  O O   . TYR B 1 77  ? 144.912 128.463 76.907  1.00 72.67  ? 23  TYR B O   1 
ATOM   2915  C CB  . TYR B 1 77  ? 146.986 130.732 76.983  1.00 69.14  ? 23  TYR B CB  1 
ATOM   2916  C CG  . TYR B 1 77  ? 147.797 130.565 78.247  1.00 61.67  ? 23  TYR B CG  1 
ATOM   2917  C CD1 . TYR B 1 77  ? 149.154 130.849 78.266  1.00 60.26  ? 23  TYR B CD1 1 
ATOM   2918  C CD2 . TYR B 1 77  ? 147.202 130.138 79.426  1.00 58.72  ? 23  TYR B CD2 1 
ATOM   2919  C CE1 . TYR B 1 77  ? 149.897 130.703 79.418  1.00 58.73  ? 23  TYR B CE1 1 
ATOM   2920  C CE2 . TYR B 1 77  ? 147.938 129.989 80.583  1.00 57.47  ? 23  TYR B CE2 1 
ATOM   2921  C CZ  . TYR B 1 77  ? 149.284 130.273 80.573  1.00 56.89  ? 23  TYR B CZ  1 
ATOM   2922  O OH  . TYR B 1 77  ? 150.024 130.128 81.724  1.00 56.94  ? 23  TYR B OH  1 
ATOM   2923  N N   . ASP B 1 78  ? 146.842 127.350 77.236  1.00 67.62  ? 24  ASP B N   1 
ATOM   2924  C CA  . ASP B 1 78  ? 146.225 126.216 77.911  1.00 64.33  ? 24  ASP B CA  1 
ATOM   2925  C C   . ASP B 1 78  ? 146.501 126.319 79.406  1.00 59.77  ? 24  ASP B C   1 
ATOM   2926  O O   . ASP B 1 78  ? 147.661 126.298 79.830  1.00 56.11  ? 24  ASP B O   1 
ATOM   2927  C CB  . ASP B 1 78  ? 146.752 124.896 77.351  1.00 64.98  ? 24  ASP B CB  1 
ATOM   2928  C CG  . ASP B 1 78  ? 145.781 123.749 77.549  1.00 69.90  ? 24  ASP B CG  1 
ATOM   2929  O OD1 . ASP B 1 78  ? 144.671 123.991 78.068  1.00 67.73  ? 24  ASP B OD1 1 
ATOM   2930  O OD2 . ASP B 1 78  ? 146.123 122.606 77.181  1.00 76.12  ? 24  ASP B OD2 1 
ATOM   2931  N N   . ILE B 1 79  ? 145.434 126.431 80.200  1.00 59.93  ? 25  ILE B N   1 
ATOM   2932  C CA  . ILE B 1 79  ? 145.575 126.555 81.645  1.00 55.10  ? 25  ILE B CA  1 
ATOM   2933  C C   . ILE B 1 79  ? 145.912 125.239 82.325  1.00 63.84  ? 25  ILE B C   1 
ATOM   2934  O O   . ILE B 1 79  ? 146.305 125.241 83.496  1.00 66.74  ? 25  ILE B O   1 
ATOM   2935  C CB  . ILE B 1 79  ? 144.289 127.139 82.263  1.00 50.52  ? 25  ILE B CB  1 
ATOM   2936  C CG1 . ILE B 1 79  ? 143.072 126.313 81.845  1.00 50.27  ? 25  ILE B CG1 1 
ATOM   2937  C CG2 . ILE B 1 79  ? 144.113 128.589 81.853  1.00 58.38  ? 25  ILE B CG2 1 
ATOM   2938  C CD1 . ILE B 1 79  ? 141.755 126.871 82.340  1.00 55.72  ? 25  ILE B CD1 1 
ATOM   2939  N N   . ARG B 1 80  ? 145.774 124.118 81.623  1.00 61.52  ? 26  ARG B N   1 
ATOM   2940  C CA  . ARG B 1 80  ? 145.982 122.804 82.213  1.00 57.23  ? 26  ARG B CA  1 
ATOM   2941  C C   . ARG B 1 80  ? 147.424 122.326 82.130  1.00 54.58  ? 26  ARG B C   1 
ATOM   2942  O O   . ARG B 1 80  ? 147.753 121.302 82.736  1.00 64.67  ? 26  ARG B O   1 
ATOM   2943  C CB  . ARG B 1 80  ? 145.067 121.783 81.539  1.00 55.78  ? 26  ARG B CB  1 
ATOM   2944  C CG  . ARG B 1 80  ? 143.604 122.164 81.595  1.00 56.58  ? 26  ARG B CG  1 
ATOM   2945  C CD  . ARG B 1 80  ? 142.813 121.453 80.520  1.00 65.52  ? 26  ARG B CD  1 
ATOM   2946  N NE  . ARG B 1 80  ? 143.366 121.700 79.193  1.00 68.78  ? 26  ARG B NE  1 
ATOM   2947  C CZ  . ARG B 1 80  ? 142.774 121.348 78.061  1.00 67.90  ? 26  ARG B CZ  1 
ATOM   2948  N NH1 . ARG B 1 80  ? 141.597 120.744 78.056  1.00 65.06  ? 26  ARG B NH1 1 
ATOM   2949  N NH2 . ARG B 1 80  ? 143.377 121.610 76.905  1.00 69.57  ? 26  ARG B NH2 1 
ATOM   2950  N N   . LEU B 1 81  ? 148.285 123.032 81.407  1.00 51.07  ? 27  LEU B N   1 
ATOM   2951  C CA  . LEU B 1 81  ? 149.669 122.624 81.216  1.00 52.78  ? 27  LEU B CA  1 
ATOM   2952  C C   . LEU B 1 81  ? 150.594 123.592 81.936  1.00 52.37  ? 27  LEU B C   1 
ATOM   2953  O O   . LEU B 1 81  ? 150.489 124.809 81.756  1.00 51.24  ? 27  LEU B O   1 
ATOM   2954  C CB  . LEU B 1 81  ? 150.023 122.566 79.730  1.00 59.93  ? 27  LEU B CB  1 
ATOM   2955  C CG  . LEU B 1 81  ? 149.121 121.711 78.841  1.00 55.06  ? 27  LEU B CG  1 
ATOM   2956  C CD1 . LEU B 1 81  ? 149.710 121.604 77.445  1.00 47.93  ? 27  LEU B CD1 1 
ATOM   2957  C CD2 . LEU B 1 81  ? 148.907 120.333 79.447  1.00 51.77  ? 27  LEU B CD2 1 
ATOM   2958  N N   . ARG B 1 82  ? 151.496 123.048 82.746  1.00 49.74  ? 28  ARG B N   1 
ATOM   2959  C CA  . ARG B 1 82  ? 152.460 123.868 83.451  1.00 50.21  ? 28  ARG B CA  1 
ATOM   2960  C C   . ARG B 1 82  ? 153.483 124.441 82.474  1.00 51.87  ? 28  ARG B C   1 
ATOM   2961  O O   . ARG B 1 82  ? 153.669 123.914 81.375  1.00 56.99  ? 28  ARG B O   1 
ATOM   2962  C CB  . ARG B 1 82  ? 153.168 123.047 84.525  1.00 50.46  ? 28  ARG B CB  1 
ATOM   2963  C CG  . ARG B 1 82  ? 154.170 122.056 83.972  1.00 51.84  ? 28  ARG B CG  1 
ATOM   2964  C CD  . ARG B 1 82  ? 155.039 121.487 85.071  1.00 54.08  ? 28  ARG B CD  1 
ATOM   2965  N NE  . ARG B 1 82  ? 156.107 120.649 84.539  1.00 56.86  ? 28  ARG B NE  1 
ATOM   2966  C CZ  . ARG B 1 82  ? 157.308 121.095 84.200  1.00 58.07  ? 28  ARG B CZ  1 
ATOM   2967  N NH1 . ARG B 1 82  ? 157.628 122.373 84.315  1.00 55.85  ? 28  ARG B NH1 1 
ATOM   2968  N NH2 . ARG B 1 82  ? 158.211 120.236 83.735  1.00 59.19  ? 28  ARG B NH2 1 
ATOM   2969  N N   . PRO B 1 83  ? 154.147 125.534 82.847  1.00 51.10  ? 29  PRO B N   1 
ATOM   2970  C CA  . PRO B 1 83  ? 155.241 126.043 82.015  1.00 56.52  ? 29  PRO B CA  1 
ATOM   2971  C C   . PRO B 1 83  ? 156.332 124.996 81.854  1.00 63.30  ? 29  PRO B C   1 
ATOM   2972  O O   . PRO B 1 83  ? 156.670 124.277 82.797  1.00 64.05  ? 29  PRO B O   1 
ATOM   2973  C CB  . PRO B 1 83  ? 155.741 127.264 82.794  1.00 53.00  ? 29  PRO B CB  1 
ATOM   2974  C CG  . PRO B 1 83  ? 154.584 127.678 83.629  1.00 51.43  ? 29  PRO B CG  1 
ATOM   2975  C CD  . PRO B 1 83  ? 153.869 126.415 83.993  1.00 51.55  ? 29  PRO B CD  1 
ATOM   2976  N N   . ASP B 1 84  ? 156.887 124.923 80.643  1.00 62.95  ? 30  ASP B N   1 
ATOM   2977  C CA  . ASP B 1 84  ? 157.892 123.919 80.293  1.00 60.55  ? 30  ASP B CA  1 
ATOM   2978  C C   . ASP B 1 84  ? 157.371 122.506 80.539  1.00 62.72  ? 30  ASP B C   1 
ATOM   2979  O O   . ASP B 1 84  ? 158.068 121.657 81.099  1.00 68.42  ? 30  ASP B O   1 
ATOM   2980  C CB  . ASP B 1 84  ? 159.202 124.156 81.045  1.00 61.35  ? 30  ASP B CB  1 
ATOM   2981  C CG  . ASP B 1 84  ? 159.843 125.478 80.691  1.00 73.38  ? 30  ASP B CG  1 
ATOM   2982  O OD1 . ASP B 1 84  ? 159.347 126.146 79.759  1.00 80.82  ? 30  ASP B OD1 1 
ATOM   2983  O OD2 . ASP B 1 84  ? 160.838 125.853 81.344  1.00 73.87  ? 30  ASP B OD2 1 
ATOM   2984  N N   . PHE B 1 85  ? 156.128 122.257 80.130  1.00 59.62  ? 31  PHE B N   1 
ATOM   2985  C CA  . PHE B 1 85  ? 155.556 120.923 80.242  1.00 57.46  ? 31  PHE B CA  1 
ATOM   2986  C C   . PHE B 1 85  ? 156.398 119.931 79.454  1.00 60.82  ? 31  PHE B C   1 
ATOM   2987  O O   . PHE B 1 85  ? 156.752 120.178 78.298  1.00 67.36  ? 31  PHE B O   1 
ATOM   2988  C CB  . PHE B 1 85  ? 154.115 120.923 79.736  1.00 53.24  ? 31  PHE B CB  1 
ATOM   2989  C CG  . PHE B 1 85  ? 153.366 119.657 80.032  1.00 55.26  ? 31  PHE B CG  1 
ATOM   2990  C CD1 . PHE B 1 85  ? 153.431 118.578 79.168  1.00 58.62  ? 31  PHE B CD1 1 
ATOM   2991  C CD2 . PHE B 1 85  ? 152.592 119.548 81.174  1.00 60.61  ? 31  PHE B CD2 1 
ATOM   2992  C CE1 . PHE B 1 85  ? 152.743 117.414 79.440  1.00 59.24  ? 31  PHE B CE1 1 
ATOM   2993  C CE2 . PHE B 1 85  ? 151.901 118.387 81.450  1.00 60.47  ? 31  PHE B CE2 1 
ATOM   2994  C CZ  . PHE B 1 85  ? 151.977 117.320 80.582  1.00 59.22  ? 31  PHE B CZ  1 
ATOM   2995  N N   . GLY B 1 86  ? 156.718 118.803 80.083  1.00 60.20  ? 32  GLY B N   1 
ATOM   2996  C CA  . GLY B 1 86  ? 157.638 117.862 79.481  1.00 62.80  ? 32  GLY B CA  1 
ATOM   2997  C C   . GLY B 1 86  ? 159.087 118.282 79.527  1.00 65.21  ? 32  GLY B C   1 
ATOM   2998  O O   . GLY B 1 86  ? 159.915 117.676 78.842  1.00 72.45  ? 32  GLY B O   1 
ATOM   2999  N N   . GLY B 1 87  ? 159.420 119.303 80.313  1.00 63.61  ? 33  GLY B N   1 
ATOM   3000  C CA  . GLY B 1 87  ? 160.773 119.794 80.397  1.00 62.86  ? 33  GLY B CA  1 
ATOM   3001  C C   . GLY B 1 87  ? 161.246 119.950 81.827  1.00 67.77  ? 33  GLY B C   1 
ATOM   3002  O O   . GLY B 1 87  ? 160.778 119.264 82.742  1.00 72.93  ? 33  GLY B O   1 
ATOM   3003  N N   . PRO B 1 88  ? 162.197 120.857 82.043  1.00 65.17  ? 34  PRO B N   1 
ATOM   3004  C CA  . PRO B 1 88  ? 162.736 121.042 83.386  1.00 63.03  ? 34  PRO B CA  1 
ATOM   3005  C C   . PRO B 1 88  ? 161.674 121.582 84.320  1.00 63.85  ? 34  PRO B C   1 
ATOM   3006  O O   . PRO B 1 88  ? 160.735 122.278 83.888  1.00 66.77  ? 34  PRO B O   1 
ATOM   3007  C CB  . PRO B 1 88  ? 163.870 122.056 83.175  1.00 61.54  ? 34  PRO B CB  1 
ATOM   3008  C CG  . PRO B 1 88  ? 164.174 122.006 81.713  1.00 64.54  ? 34  PRO B CG  1 
ATOM   3009  C CD  . PRO B 1 88  ? 162.872 121.708 81.051  1.00 64.65  ? 34  PRO B CD  1 
ATOM   3010  N N   . PRO B 1 89  ? 161.773 121.278 85.614  1.00 61.78  ? 35  PRO B N   1 
ATOM   3011  C CA  . PRO B 1 89  ? 160.800 121.813 86.572  1.00 58.82  ? 35  PRO B CA  1 
ATOM   3012  C C   . PRO B 1 89  ? 160.858 123.332 86.634  1.00 57.56  ? 35  PRO B C   1 
ATOM   3013  O O   . PRO B 1 89  ? 161.929 123.937 86.564  1.00 58.55  ? 35  PRO B O   1 
ATOM   3014  C CB  . PRO B 1 89  ? 161.225 121.178 87.899  1.00 54.56  ? 35  PRO B CB  1 
ATOM   3015  C CG  . PRO B 1 89  ? 162.669 120.858 87.714  1.00 58.43  ? 35  PRO B CG  1 
ATOM   3016  C CD  . PRO B 1 89  ? 162.809 120.468 86.274  1.00 62.73  ? 35  PRO B CD  1 
ATOM   3017  N N   . VAL B 1 90  ? 159.687 123.945 86.771  1.00 53.01  ? 36  VAL B N   1 
ATOM   3018  C CA  . VAL B 1 90  ? 159.585 125.398 86.841  1.00 49.84  ? 36  VAL B CA  1 
ATOM   3019  C C   . VAL B 1 90  ? 159.870 125.844 88.270  1.00 53.37  ? 36  VAL B C   1 
ATOM   3020  O O   . VAL B 1 90  ? 159.188 125.427 89.211  1.00 56.19  ? 36  VAL B O   1 
ATOM   3021  C CB  . VAL B 1 90  ? 158.204 125.878 86.370  1.00 50.50  ? 36  VAL B CB  1 
ATOM   3022  C CG1 . VAL B 1 90  ? 157.109 124.974 86.912  1.00 47.82  ? 36  VAL B CG1 1 
ATOM   3023  C CG2 . VAL B 1 90  ? 157.970 127.316 86.794  1.00 51.61  ? 36  VAL B CG2 1 
ATOM   3024  N N   . CYS B 1 91  ? 160.886 126.686 88.436  1.00 52.96  ? 37  CYS B N   1 
ATOM   3025  C CA  . CYS B 1 91  ? 161.214 127.206 89.756  1.00 47.29  ? 37  CYS B CA  1 
ATOM   3026  C C   . CYS B 1 91  ? 160.207 128.275 90.156  1.00 43.54  ? 37  CYS B C   1 
ATOM   3027  O O   . CYS B 1 91  ? 159.936 129.205 89.392  1.00 52.48  ? 37  CYS B O   1 
ATOM   3028  C CB  . CYS B 1 91  ? 162.629 127.778 89.766  1.00 49.05  ? 37  CYS B CB  1 
ATOM   3029  S SG  . CYS B 1 91  ? 163.920 126.591 89.334  1.00 75.87  ? 37  CYS B SG  1 
ATOM   3030  N N   . VAL B 1 92  ? 159.653 128.143 91.357  1.00 40.29  ? 38  VAL B N   1 
ATOM   3031  C CA  . VAL B 1 92  ? 158.627 129.049 91.860  1.00 38.21  ? 38  VAL B CA  1 
ATOM   3032  C C   . VAL B 1 92  ? 159.124 129.602 93.188  1.00 36.74  ? 38  VAL B C   1 
ATOM   3033  O O   . VAL B 1 92  ? 158.997 128.949 94.229  1.00 41.63  ? 38  VAL B O   1 
ATOM   3034  C CB  . VAL B 1 92  ? 157.269 128.356 92.022  1.00 34.21  ? 38  VAL B CB  1 
ATOM   3035  C CG1 . VAL B 1 92  ? 156.227 129.348 92.508  1.00 30.02  ? 38  VAL B CG1 1 
ATOM   3036  C CG2 . VAL B 1 92  ? 156.834 127.716 90.715  1.00 33.63  ? 38  VAL B CG2 1 
ATOM   3037  N N   . GLY B 1 93  ? 159.691 130.808 93.162  1.00 34.08  ? 39  GLY B N   1 
ATOM   3038  C CA  . GLY B 1 93  ? 160.088 131.451 94.394  1.00 40.54  ? 39  GLY B CA  1 
ATOM   3039  C C   . GLY B 1 93  ? 158.898 132.005 95.149  1.00 40.22  ? 39  GLY B C   1 
ATOM   3040  O O   . GLY B 1 93  ? 157.849 132.289 94.580  1.00 45.36  ? 39  GLY B O   1 
ATOM   3041  N N   . MET B 1 94  ? 159.056 132.156 96.460  1.00 37.15  ? 40  MET B N   1 
ATOM   3042  C CA  . MET B 1 94  ? 157.943 132.582 97.290  1.00 37.93  ? 40  MET B CA  1 
ATOM   3043  C C   . MET B 1 94  ? 158.392 133.619 98.303  1.00 41.98  ? 40  MET B C   1 
ATOM   3044  O O   . MET B 1 94  ? 159.550 133.641 98.726  1.00 47.08  ? 40  MET B O   1 
ATOM   3045  C CB  . MET B 1 94  ? 157.308 131.402 98.031  1.00 34.73  ? 40  MET B CB  1 
ATOM   3046  C CG  . MET B 1 94  ? 156.676 130.375 97.127  1.00 35.54  ? 40  MET B CG  1 
ATOM   3047  S SD  . MET B 1 94  ? 155.887 129.058 98.055  1.00 53.30  ? 40  MET B SD  1 
ATOM   3048  C CE  . MET B 1 94  ? 155.255 128.066 96.714  1.00 46.71  ? 40  MET B CE  1 
ATOM   3049  N N   A ASN B 1 95  ? 157.460 134.480 98.693  0.50 42.17  ? 41  ASN B N   1 
ATOM   3050  N N   B ASN B 1 95  ? 157.450 134.484 98.680  0.50 42.14  ? 41  ASN B N   1 
ATOM   3051  C CA  A ASN B 1 95  ? 157.706 135.374 99.810  0.50 42.43  ? 41  ASN B CA  1 
ATOM   3052  C CA  B ASN B 1 95  ? 157.640 135.470 99.734  0.50 42.43  ? 41  ASN B CA  1 
ATOM   3053  C C   A ASN B 1 95  ? 156.406 135.575 100.572 0.50 43.13  ? 41  ASN B C   1 
ATOM   3054  C C   B ASN B 1 95  ? 156.377 135.551 100.578 0.50 43.11  ? 41  ASN B C   1 
ATOM   3055  O O   A ASN B 1 95  ? 155.309 135.406 100.033 0.50 42.90  ? 41  ASN B O   1 
ATOM   3056  O O   B ASN B 1 95  ? 155.270 135.303 100.090 0.50 42.89  ? 41  ASN B O   1 
ATOM   3057  C CB  A ASN B 1 95  ? 158.307 136.711 99.354  0.50 42.78  ? 41  ASN B CB  1 
ATOM   3058  C CB  B ASN B 1 95  ? 157.966 136.858 99.173  0.50 43.19  ? 41  ASN B CB  1 
ATOM   3059  C CG  A ASN B 1 95  ? 157.413 137.460 98.395  0.50 44.99  ? 41  ASN B CG  1 
ATOM   3060  C CG  B ASN B 1 95  ? 159.278 136.892 98.428  0.50 45.82  ? 41  ASN B CG  1 
ATOM   3061  O OD1 A ASN B 1 95  ? 157.529 137.319 97.178  0.50 46.67  ? 41  ASN B OD1 1 
ATOM   3062  O OD1 B ASN B 1 95  ? 159.360 137.405 97.313  0.50 48.40  ? 41  ASN B OD1 1 
ATOM   3063  N ND2 A ASN B 1 95  ? 156.521 138.275 98.939  0.50 46.52  ? 41  ASN B ND2 1 
ATOM   3064  N ND2 B ASN B 1 95  ? 160.319 136.342 99.041  0.50 47.79  ? 41  ASN B ND2 1 
ATOM   3065  N N   . ILE B 1 96  ? 156.548 135.914 101.849 1.00 44.74  ? 42  ILE B N   1 
ATOM   3066  C CA  . ILE B 1 96  ? 155.428 136.068 102.767 1.00 41.78  ? 42  ILE B CA  1 
ATOM   3067  C C   . ILE B 1 96  ? 155.618 137.360 103.545 1.00 50.64  ? 42  ILE B C   1 
ATOM   3068  O O   . ILE B 1 96  ? 156.708 137.627 104.059 1.00 59.70  ? 42  ILE B O   1 
ATOM   3069  C CB  . ILE B 1 96  ? 155.308 134.872 103.733 1.00 40.31  ? 42  ILE B CB  1 
ATOM   3070  C CG1 . ILE B 1 96  ? 154.943 133.598 102.970 1.00 42.97  ? 42  ILE B CG1 1 
ATOM   3071  C CG2 . ILE B 1 96  ? 154.287 135.157 104.818 1.00 43.36  ? 42  ILE B CG2 1 
ATOM   3072  C CD1 . ILE B 1 96  ? 154.804 132.380 103.851 1.00 46.60  ? 42  ILE B CD1 1 
ATOM   3073  N N   . ASP B 1 97  ? 154.561 138.161 103.631 1.00 50.40  ? 43  ASP B N   1 
ATOM   3074  C CA  . ASP B 1 97  ? 154.541 139.361 104.460 1.00 53.17  ? 43  ASP B CA  1 
ATOM   3075  C C   . ASP B 1 97  ? 153.436 139.181 105.490 1.00 53.20  ? 43  ASP B C   1 
ATOM   3076  O O   . ASP B 1 97  ? 152.252 139.223 105.145 1.00 56.25  ? 43  ASP B O   1 
ATOM   3077  C CB  . ASP B 1 97  ? 154.317 140.613 103.616 1.00 52.98  ? 43  ASP B CB  1 
ATOM   3078  C CG  . ASP B 1 97  ? 154.569 141.889 104.392 1.00 68.48  ? 43  ASP B CG  1 
ATOM   3079  O OD1 . ASP B 1 97  ? 155.204 141.818 105.464 1.00 73.16  ? 43  ASP B OD1 1 
ATOM   3080  O OD2 . ASP B 1 97  ? 154.129 142.963 103.931 1.00 67.95  ? 43  ASP B OD2 1 
ATOM   3081  N N   . ILE B 1 98  ? 153.817 138.983 106.747 1.00 49.38  ? 44  ILE B N   1 
ATOM   3082  C CA  . ILE B 1 98  ? 152.864 138.622 107.792 1.00 48.38  ? 44  ILE B CA  1 
ATOM   3083  C C   . ILE B 1 98  ? 152.219 139.895 108.329 1.00 52.73  ? 44  ILE B C   1 
ATOM   3084  O O   . ILE B 1 98  ? 152.874 140.701 108.991 1.00 60.59  ? 44  ILE B O   1 
ATOM   3085  C CB  . ILE B 1 98  ? 153.544 137.833 108.913 1.00 50.45  ? 44  ILE B CB  1 
ATOM   3086  C CG1 . ILE B 1 98  ? 154.094 136.517 108.368 1.00 49.14  ? 44  ILE B CG1 1 
ATOM   3087  C CG2 . ILE B 1 98  ? 152.571 137.591 110.050 1.00 52.08  ? 44  ILE B CG2 1 
ATOM   3088  C CD1 . ILE B 1 98  ? 155.002 135.804 109.324 1.00 57.76  ? 44  ILE B CD1 1 
ATOM   3089  N N   . ALA B 1 99  ? 150.927 140.077 108.045 1.00 46.82  ? 45  ALA B N   1 
ATOM   3090  C CA  . ALA B 1 99  ? 150.218 141.238 108.566 1.00 48.12  ? 45  ALA B CA  1 
ATOM   3091  C C   . ALA B 1 99  ? 150.047 141.142 110.077 1.00 54.73  ? 45  ALA B C   1 
ATOM   3092  O O   . ALA B 1 99  ? 150.310 142.107 110.804 1.00 62.33  ? 45  ALA B O   1 
ATOM   3093  C CB  . ALA B 1 99  ? 148.862 141.378 107.876 1.00 44.11  ? 45  ALA B CB  1 
ATOM   3094  N N   . SER B 1 100 ? 149.614 139.984 110.569 1.00 50.88  ? 46  SER B N   1 
ATOM   3095  C CA  . SER B 1 100 ? 149.378 139.794 111.994 1.00 52.15  ? 46  SER B CA  1 
ATOM   3096  C C   . SER B 1 100 ? 149.235 138.306 112.281 1.00 49.77  ? 46  SER B C   1 
ATOM   3097  O O   . SER B 1 100 ? 149.034 137.494 111.375 1.00 52.36  ? 46  SER B O   1 
ATOM   3098  C CB  . SER B 1 100 ? 148.130 140.548 112.460 1.00 60.52  ? 46  SER B CB  1 
ATOM   3099  O OG  . SER B 1 100 ? 146.966 140.039 111.831 1.00 57.36  ? 46  SER B OG  1 
ATOM   3100  N N   . ILE B 1 101 ? 149.340 137.964 113.561 1.00 52.98  ? 47  ILE B N   1 
ATOM   3101  C CA  . ILE B 1 101 ? 148.986 136.646 114.076 1.00 51.83  ? 47  ILE B CA  1 
ATOM   3102  C C   . ILE B 1 101 ? 147.801 136.877 115.004 1.00 56.59  ? 47  ILE B C   1 
ATOM   3103  O O   . ILE B 1 101 ? 147.972 137.323 116.144 1.00 62.55  ? 47  ILE B O   1 
ATOM   3104  C CB  . ILE B 1 101 ? 150.149 135.965 114.803 1.00 49.88  ? 47  ILE B CB  1 
ATOM   3105  C CG1 . ILE B 1 101 ? 151.317 135.741 113.841 1.00 49.39  ? 47  ILE B CG1 1 
ATOM   3106  C CG2 . ILE B 1 101 ? 149.698 134.647 115.408 1.00 54.52  ? 47  ILE B CG2 1 
ATOM   3107  C CD1 . ILE B 1 101 ? 152.476 134.991 114.451 1.00 52.31  ? 47  ILE B CD1 1 
ATOM   3108  N N   . ASP B 1 102 ? 146.594 136.585 114.513 1.00 58.85  ? 48  ASP B N   1 
ATOM   3109  C CA  . ASP B 1 102 ? 145.383 137.044 115.187 1.00 64.86  ? 48  ASP B CA  1 
ATOM   3110  C C   . ASP B 1 102 ? 145.230 136.417 116.567 1.00 62.05  ? 48  ASP B C   1 
ATOM   3111  O O   . ASP B 1 102 ? 145.014 137.125 117.557 1.00 74.08  ? 48  ASP B O   1 
ATOM   3112  C CB  . ASP B 1 102 ? 144.160 136.750 114.319 1.00 70.42  ? 48  ASP B CB  1 
ATOM   3113  C CG  . ASP B 1 102 ? 144.144 137.569 113.044 1.00 79.54  ? 48  ASP B CG  1 
ATOM   3114  O OD1 . ASP B 1 102 ? 145.110 138.326 112.813 1.00 70.61  ? 48  ASP B OD1 1 
ATOM   3115  O OD2 . ASP B 1 102 ? 143.167 137.460 112.274 1.00 85.22  ? 48  ASP B OD2 1 
ATOM   3116  N N   . MET B 1 103 ? 145.345 135.095 116.659 1.00 53.44  ? 49  MET B N   1 
ATOM   3117  C CA  . MET B 1 103 ? 145.149 134.430 117.937 1.00 55.31  ? 49  MET B CA  1 
ATOM   3118  C C   . MET B 1 103 ? 145.981 133.160 117.986 1.00 54.19  ? 49  MET B C   1 
ATOM   3119  O O   . MET B 1 103 ? 146.322 132.580 116.953 1.00 60.77  ? 49  MET B O   1 
ATOM   3120  C CB  . MET B 1 103 ? 143.673 134.096 118.179 1.00 58.03  ? 49  MET B CB  1 
ATOM   3121  C CG  . MET B 1 103 ? 143.187 132.856 117.451 1.00 65.01  ? 49  MET B CG  1 
ATOM   3122  S SD  . MET B 1 103 ? 141.430 132.546 117.706 1.00 97.18  ? 49  MET B SD  1 
ATOM   3123  C CE  . MET B 1 103 ? 140.714 133.929 116.824 1.00 75.91  ? 49  MET B CE  1 
ATOM   3124  N N   . VAL B 1 104 ? 146.313 132.745 119.205 1.00 52.83  ? 50  VAL B N   1 
ATOM   3125  C CA  . VAL B 1 104 ? 146.988 131.481 119.474 1.00 53.12  ? 50  VAL B CA  1 
ATOM   3126  C C   . VAL B 1 104 ? 146.211 130.788 120.581 1.00 59.31  ? 50  VAL B C   1 
ATOM   3127  O O   . VAL B 1 104 ? 146.105 131.321 121.692 1.00 69.72  ? 50  VAL B O   1 
ATOM   3128  C CB  . VAL B 1 104 ? 148.456 131.685 119.884 1.00 50.97  ? 50  VAL B CB  1 
ATOM   3129  C CG1 . VAL B 1 104 ? 149.082 130.364 120.272 1.00 53.98  ? 50  VAL B CG1 1 
ATOM   3130  C CG2 . VAL B 1 104 ? 149.242 132.344 118.760 1.00 43.50  ? 50  VAL B CG2 1 
ATOM   3131  N N   . SER B 1 105 ? 145.670 129.606 120.291 1.00 55.46  ? 51  SER B N   1 
ATOM   3132  C CA  . SER B 1 105 ? 144.767 128.917 121.201 1.00 62.77  ? 51  SER B CA  1 
ATOM   3133  C C   . SER B 1 105 ? 145.308 127.534 121.527 1.00 64.58  ? 51  SER B C   1 
ATOM   3134  O O   . SER B 1 105 ? 145.677 126.775 120.623 1.00 62.67  ? 51  SER B O   1 
ATOM   3135  C CB  . SER B 1 105 ? 143.364 128.805 120.599 1.00 63.22  ? 51  SER B CB  1 
ATOM   3136  O OG  . SER B 1 105 ? 142.460 128.217 121.517 1.00 69.65  ? 51  SER B OG  1 
ATOM   3137  N N   . GLU B 1 106 ? 145.344 127.213 122.823 1.00 67.69  ? 52  GLU B N   1 
ATOM   3138  C CA  . GLU B 1 106 ? 145.739 125.895 123.299 1.00 61.99  ? 52  GLU B CA  1 
ATOM   3139  C C   . GLU B 1 106 ? 144.560 124.947 123.449 1.00 61.48  ? 52  GLU B C   1 
ATOM   3140  O O   . GLU B 1 106 ? 144.758 123.727 123.448 1.00 64.95  ? 52  GLU B O   1 
ATOM   3141  C CB  . GLU B 1 106 ? 146.464 126.005 124.646 1.00 61.10  ? 52  GLU B CB  1 
ATOM   3142  C CG  . GLU B 1 106 ? 147.710 126.878 124.633 1.00 62.56  ? 52  GLU B CG  1 
ATOM   3143  C CD  . GLU B 1 106 ? 147.396 128.357 124.752 1.00 75.81  ? 52  GLU B CD  1 
ATOM   3144  O OE1 . GLU B 1 106 ? 146.289 128.694 125.220 1.00 71.39  ? 52  GLU B OE1 1 
ATOM   3145  O OE2 . GLU B 1 106 ? 148.254 129.181 124.373 1.00 79.75  ? 52  GLU B OE2 1 
ATOM   3146  N N   . VAL B 1 107 ? 143.344 125.478 123.593 1.00 60.02  ? 53  VAL B N   1 
ATOM   3147  C CA  . VAL B 1 107 ? 142.159 124.626 123.617 1.00 61.80  ? 53  VAL B CA  1 
ATOM   3148  C C   . VAL B 1 107 ? 141.985 123.931 122.275 1.00 68.08  ? 53  VAL B C   1 
ATOM   3149  O O   . VAL B 1 107 ? 141.610 122.754 122.209 1.00 74.71  ? 53  VAL B O   1 
ATOM   3150  C CB  . VAL B 1 107 ? 140.917 125.452 123.997 1.00 66.19  ? 53  VAL B CB  1 
ATOM   3151  C CG1 . VAL B 1 107 ? 139.673 124.581 123.995 1.00 65.90  ? 53  VAL B CG1 1 
ATOM   3152  C CG2 . VAL B 1 107 ? 141.116 126.101 125.357 1.00 69.62  ? 53  VAL B CG2 1 
ATOM   3153  N N   . ASN B 1 108 ? 142.261 124.646 121.184 1.00 67.46  ? 54  ASN B N   1 
ATOM   3154  C CA  . ASN B 1 108 ? 142.220 124.074 119.846 1.00 64.70  ? 54  ASN B CA  1 
ATOM   3155  C C   . ASN B 1 108 ? 143.600 123.764 119.284 1.00 62.32  ? 54  ASN B C   1 
ATOM   3156  O O   . ASN B 1 108 ? 143.690 123.087 118.254 1.00 61.73  ? 54  ASN B O   1 
ATOM   3157  C CB  . ASN B 1 108 ? 141.491 125.021 118.885 1.00 64.50  ? 54  ASN B CB  1 
ATOM   3158  C CG  . ASN B 1 108 ? 140.007 125.112 119.170 1.00 68.77  ? 54  ASN B CG  1 
ATOM   3159  O OD1 . ASN B 1 108 ? 139.352 124.107 119.442 1.00 67.29  ? 54  ASN B OD1 1 
ATOM   3160  N ND2 . ASN B 1 108 ? 139.468 126.324 119.110 1.00 74.15  ? 54  ASN B ND2 1 
ATOM   3161  N N   . MET B 1 109 ? 144.663 124.251 119.927 1.00 62.69  ? 55  MET B N   1 
ATOM   3162  C CA  . MET B 1 109 ? 146.041 123.985 119.516 1.00 62.37  ? 55  MET B CA  1 
ATOM   3163  C C   . MET B 1 109 ? 146.302 124.493 118.096 1.00 59.80  ? 55  MET B C   1 
ATOM   3164  O O   . MET B 1 109 ? 146.761 123.759 117.219 1.00 56.51  ? 55  MET B O   1 
ATOM   3165  C CB  . MET B 1 109 ? 146.367 122.490 119.630 1.00 64.50  ? 55  MET B CB  1 
ATOM   3166  C CG  . MET B 1 109 ? 146.336 121.935 121.043 1.00 65.73  ? 55  MET B CG  1 
ATOM   3167  S SD  . MET B 1 109 ? 147.837 122.308 121.964 1.00 79.65  ? 55  MET B SD  1 
ATOM   3168  C CE  . MET B 1 109 ? 147.535 121.406 123.479 1.00 70.91  ? 55  MET B CE  1 
ATOM   3169  N N   . ASP B 1 110 ? 146.001 125.772 117.879 1.00 60.89  ? 56  ASP B N   1 
ATOM   3170  C CA  . ASP B 1 110 ? 146.175 126.340 116.548 1.00 55.09  ? 56  ASP B CA  1 
ATOM   3171  C C   . ASP B 1 110 ? 146.339 127.849 116.646 1.00 56.36  ? 56  ASP B C   1 
ATOM   3172  O O   . ASP B 1 110 ? 145.971 128.472 117.644 1.00 69.38  ? 56  ASP B O   1 
ATOM   3173  C CB  . ASP B 1 110 ? 145.001 125.985 115.627 1.00 54.79  ? 56  ASP B CB  1 
ATOM   3174  C CG  . ASP B 1 110 ? 143.656 126.380 116.208 1.00 63.80  ? 56  ASP B CG  1 
ATOM   3175  O OD1 . ASP B 1 110 ? 143.618 126.937 117.324 1.00 69.56  ? 56  ASP B OD1 1 
ATOM   3176  O OD2 . ASP B 1 110 ? 142.629 126.127 115.546 1.00 66.64  ? 56  ASP B OD2 1 
ATOM   3177  N N   . TYR B 1 111 ? 146.880 128.431 115.579 1.00 48.76  ? 57  TYR B N   1 
ATOM   3178  C CA  . TYR B 1 111 ? 147.114 129.864 115.515 1.00 46.55  ? 57  TYR B CA  1 
ATOM   3179  C C   . TYR B 1 111 ? 146.592 130.412 114.196 1.00 48.06  ? 57  TYR B C   1 
ATOM   3180  O O   . TYR B 1 111 ? 146.722 129.770 113.152 1.00 55.68  ? 57  TYR B O   1 
ATOM   3181  C CB  . TYR B 1 111 ? 148.606 130.192 115.672 1.00 46.19  ? 57  TYR B CB  1 
ATOM   3182  C CG  . TYR B 1 111 ? 149.474 129.713 114.530 1.00 52.71  ? 57  TYR B CG  1 
ATOM   3183  C CD1 . TYR B 1 111 ? 149.952 128.412 114.493 1.00 57.87  ? 57  TYR B CD1 1 
ATOM   3184  C CD2 . TYR B 1 111 ? 149.822 130.566 113.494 1.00 54.29  ? 57  TYR B CD2 1 
ATOM   3185  C CE1 . TYR B 1 111 ? 150.745 127.973 113.452 1.00 60.72  ? 57  TYR B CE1 1 
ATOM   3186  C CE2 . TYR B 1 111 ? 150.613 130.136 112.450 1.00 58.00  ? 57  TYR B CE2 1 
ATOM   3187  C CZ  . TYR B 1 111 ? 151.073 128.839 112.435 1.00 61.52  ? 57  TYR B CZ  1 
ATOM   3188  O OH  . TYR B 1 111 ? 151.863 128.405 111.397 1.00 63.93  ? 57  TYR B OH  1 
ATOM   3189  N N   . THR B 1 112 ? 146.010 131.603 114.250 1.00 49.12  ? 58  THR B N   1 
ATOM   3190  C CA  . THR B 1 112 ? 145.503 132.282 113.066 1.00 48.86  ? 58  THR B CA  1 
ATOM   3191  C C   . THR B 1 112 ? 146.548 133.265 112.558 1.00 52.79  ? 58  THR B C   1 
ATOM   3192  O O   . THR B 1 112 ? 147.211 133.943 113.346 1.00 58.65  ? 58  THR B O   1 
ATOM   3193  C CB  . THR B 1 112 ? 144.196 133.015 113.365 1.00 50.23  ? 58  THR B CB  1 
ATOM   3194  O OG1 . THR B 1 112 ? 143.330 132.159 114.117 1.00 48.75  ? 58  THR B OG1 1 
ATOM   3195  C CG2 . THR B 1 112 ? 143.502 133.402 112.072 1.00 53.23  ? 58  THR B CG2 1 
ATOM   3196  N N   . LEU B 1 113 ? 146.688 133.342 111.238 1.00 48.94  ? 59  LEU B N   1 
ATOM   3197  C CA  . LEU B 1 113 ? 147.762 134.107 110.624 1.00 48.20  ? 59  LEU B CA  1 
ATOM   3198  C C   . LEU B 1 113 ? 147.270 134.726 109.327 1.00 46.08  ? 59  LEU B C   1 
ATOM   3199  O O   . LEU B 1 113 ? 146.792 134.013 108.443 1.00 51.17  ? 59  LEU B O   1 
ATOM   3200  C CB  . LEU B 1 113 ? 148.970 133.207 110.355 1.00 45.74  ? 59  LEU B CB  1 
ATOM   3201  C CG  . LEU B 1 113 ? 150.126 133.778 109.542 1.00 45.12  ? 59  LEU B CG  1 
ATOM   3202  C CD1 . LEU B 1 113 ? 151.210 134.291 110.465 1.00 48.64  ? 59  LEU B CD1 1 
ATOM   3203  C CD2 . LEU B 1 113 ? 150.671 132.716 108.611 1.00 47.18  ? 59  LEU B CD2 1 
ATOM   3204  N N   . THR B 1 114 ? 147.395 136.044 109.214 1.00 43.72  ? 60  THR B N   1 
ATOM   3205  C CA  . THR B 1 114 ? 147.030 136.775 108.009 1.00 42.04  ? 60  THR B CA  1 
ATOM   3206  C C   . THR B 1 114 ? 148.303 137.215 107.303 1.00 44.80  ? 60  THR B C   1 
ATOM   3207  O O   . THR B 1 114 ? 149.221 137.738 107.942 1.00 51.60  ? 60  THR B O   1 
ATOM   3208  C CB  . THR B 1 114 ? 146.160 137.987 108.341 1.00 45.88  ? 60  THR B CB  1 
ATOM   3209  O OG1 . THR B 1 114 ? 145.032 137.569 109.118 1.00 56.87  ? 60  THR B OG1 1 
ATOM   3210  C CG2 . THR B 1 114 ? 145.667 138.654 107.069 1.00 39.76  ? 60  THR B CG2 1 
ATOM   3211  N N   . MET B 1 115 ? 148.364 137.004 105.991 1.00 40.59  ? 61  MET B N   1 
ATOM   3212  C CA  . MET B 1 115 ? 149.614 137.271 105.298 1.00 38.63  ? 61  MET B CA  1 
ATOM   3213  C C   . MET B 1 115 ? 149.368 137.571 103.829 1.00 39.69  ? 61  MET B C   1 
ATOM   3214  O O   . MET B 1 115 ? 148.376 137.129 103.241 1.00 43.54  ? 61  MET B O   1 
ATOM   3215  C CB  . MET B 1 115 ? 150.577 136.089 105.428 1.00 44.64  ? 61  MET B CB  1 
ATOM   3216  C CG  . MET B 1 115 ? 150.004 134.790 104.901 1.00 42.18  ? 61  MET B CG  1 
ATOM   3217  S SD  . MET B 1 115 ? 151.128 133.398 105.070 1.00 56.89  ? 61  MET B SD  1 
ATOM   3218  C CE  . MET B 1 115 ? 150.030 132.055 104.646 1.00 45.27  ? 61  MET B CE  1 
ATOM   3219  N N   . TYR B 1 116 ? 150.295 138.329 103.251 1.00 38.52  ? 62  TYR B N   1 
ATOM   3220  C CA  . TYR B 1 116 ? 150.406 138.494 101.807 1.00 40.21  ? 62  TYR B CA  1 
ATOM   3221  C C   . TYR B 1 116 ? 151.387 137.445 101.301 1.00 43.83  ? 62  TYR B C   1 
ATOM   3222  O O   . TYR B 1 116 ? 152.577 137.489 101.626 1.00 54.33  ? 62  TYR B O   1 
ATOM   3223  C CB  . TYR B 1 116 ? 150.879 139.901 101.451 1.00 40.84  ? 62  TYR B CB  1 
ATOM   3224  C CG  . TYR B 1 116 ? 150.126 141.005 102.154 1.00 43.68  ? 62  TYR B CG  1 
ATOM   3225  C CD1 . TYR B 1 116 ? 150.553 141.486 103.383 1.00 48.10  ? 62  TYR B CD1 1 
ATOM   3226  C CD2 . TYR B 1 116 ? 148.993 141.569 101.588 1.00 38.80  ? 62  TYR B CD2 1 
ATOM   3227  C CE1 . TYR B 1 116 ? 149.871 142.493 104.030 1.00 46.51  ? 62  TYR B CE1 1 
ATOM   3228  C CE2 . TYR B 1 116 ? 148.306 142.579 102.228 1.00 37.37  ? 62  TYR B CE2 1 
ATOM   3229  C CZ  . TYR B 1 116 ? 148.749 143.036 103.448 1.00 46.55  ? 62  TYR B CZ  1 
ATOM   3230  O OH  . TYR B 1 116 ? 148.066 144.040 104.091 1.00 58.17  ? 62  TYR B OH  1 
ATOM   3231  N N   . PHE B 1 117 ? 150.886 136.506 100.511 1.00 33.09  ? 63  PHE B N   1 
ATOM   3232  C CA  . PHE B 1 117 ? 151.651 135.375 100.009 1.00 35.60  ? 63  PHE B CA  1 
ATOM   3233  C C   . PHE B 1 117 ? 151.881 135.589 98.520  1.00 37.77  ? 63  PHE B C   1 
ATOM   3234  O O   . PHE B 1 117 ? 150.917 135.675 97.752  1.00 40.91  ? 63  PHE B O   1 
ATOM   3235  C CB  . PHE B 1 117 ? 150.891 134.075 100.275 1.00 36.29  ? 63  PHE B CB  1 
ATOM   3236  C CG  . PHE B 1 117 ? 151.605 132.842 99.822  1.00 36.67  ? 63  PHE B CG  1 
ATOM   3237  C CD1 . PHE B 1 117 ? 152.587 132.270 100.607 1.00 40.55  ? 63  PHE B CD1 1 
ATOM   3238  C CD2 . PHE B 1 117 ? 151.275 132.238 98.623  1.00 33.38  ? 63  PHE B CD2 1 
ATOM   3239  C CE1 . PHE B 1 117 ? 153.240 131.131 100.197 1.00 40.09  ? 63  PHE B CE1 1 
ATOM   3240  C CE2 . PHE B 1 117 ? 151.924 131.098 98.209  1.00 36.10  ? 63  PHE B CE2 1 
ATOM   3241  C CZ  . PHE B 1 117 ? 152.908 130.544 98.997  1.00 35.78  ? 63  PHE B CZ  1 
ATOM   3242  N N   . GLN B 1 118 ? 153.145 135.692 98.113  1.00 38.32  ? 64  GLN B N   1 
ATOM   3243  C CA  . GLN B 1 118 ? 153.490 136.040 96.742  1.00 39.16  ? 64  GLN B CA  1 
ATOM   3244  C C   . GLN B 1 118 ? 154.329 134.934 96.124  1.00 41.82  ? 64  GLN B C   1 
ATOM   3245  O O   . GLN B 1 118 ? 155.285 134.454 96.743  1.00 47.69  ? 64  GLN B O   1 
ATOM   3246  C CB  . GLN B 1 118 ? 154.248 137.365 96.687  1.00 40.71  ? 64  GLN B CB  1 
ATOM   3247  C CG  . GLN B 1 118 ? 153.542 138.513 97.373  1.00 45.71  ? 64  GLN B CG  1 
ATOM   3248  C CD  . GLN B 1 118 ? 154.375 139.774 97.378  1.00 56.39  ? 64  GLN B CD  1 
ATOM   3249  O OE1 . GLN B 1 118 ? 155.294 139.925 96.575  1.00 61.02  ? 64  GLN B OE1 1 
ATOM   3250  N NE2 . GLN B 1 118 ? 154.070 140.682 98.296  1.00 59.82  ? 64  GLN B NE2 1 
ATOM   3251  N N   . GLN B 1 119 ? 153.972 134.545 94.903  1.00 38.31  ? 65  GLN B N   1 
ATOM   3252  C CA  . GLN B 1 119 ? 154.680 133.532 94.135  1.00 33.42  ? 65  GLN B CA  1 
ATOM   3253  C C   . GLN B 1 119 ? 155.262 134.175 92.885  1.00 35.80  ? 65  GLN B C   1 
ATOM   3254  O O   . GLN B 1 119 ? 154.583 134.948 92.203  1.00 42.02  ? 65  GLN B O   1 
ATOM   3255  C CB  . GLN B 1 119 ? 153.752 132.377 93.759  1.00 33.33  ? 65  GLN B CB  1 
ATOM   3256  C CG  . GLN B 1 119 ? 153.073 131.727 94.946  1.00 38.04  ? 65  GLN B CG  1 
ATOM   3257  C CD  . GLN B 1 119 ? 152.118 130.627 94.542  1.00 36.54  ? 65  GLN B CD  1 
ATOM   3258  O OE1 . GLN B 1 119 ? 152.536 129.518 94.216  1.00 41.82  ? 65  GLN B OE1 1 
ATOM   3259  N NE2 . GLN B 1 119 ? 150.826 130.929 94.559  1.00 28.75  ? 65  GLN B NE2 1 
ATOM   3260  N N   . TYR B 1 120 ? 156.514 133.847 92.591  1.00 37.39  ? 66  TYR B N   1 
ATOM   3261  C CA  A TYR B 1 120 ? 157.262 134.423 91.483  0.50 40.66  ? 66  TYR B CA  1 
ATOM   3262  C CA  B TYR B 1 120 ? 157.257 134.422 91.477  0.50 40.69  ? 66  TYR B CA  1 
ATOM   3263  C C   . TYR B 1 120 ? 157.762 133.288 90.601  1.00 39.34  ? 66  TYR B C   1 
ATOM   3264  O O   . TYR B 1 120 ? 158.530 132.439 91.062  1.00 45.10  ? 66  TYR B O   1 
ATOM   3265  C CB  A TYR B 1 120 ? 158.424 135.259 92.025  0.50 46.56  ? 66  TYR B CB  1 
ATOM   3266  C CB  B TYR B 1 120 ? 158.435 135.266 91.970  0.50 46.62  ? 66  TYR B CB  1 
ATOM   3267  C CG  A TYR B 1 120 ? 159.269 135.974 90.999  0.50 49.11  ? 66  TYR B CG  1 
ATOM   3268  C CG  B TYR B 1 120 ? 158.065 136.484 92.788  0.50 48.64  ? 66  TYR B CG  1 
ATOM   3269  C CD1 A TYR B 1 120 ? 158.966 137.269 90.606  0.50 48.62  ? 66  TYR B CD1 1 
ATOM   3270  C CD1 B TYR B 1 120 ? 157.661 136.364 94.111  0.50 47.43  ? 66  TYR B CD1 1 
ATOM   3271  C CD2 A TYR B 1 120 ? 160.392 135.368 90.451  0.50 49.11  ? 66  TYR B CD2 1 
ATOM   3272  C CD2 B TYR B 1 120 ? 158.151 137.758 92.245  0.50 48.42  ? 66  TYR B CD2 1 
ATOM   3273  C CE1 A TYR B 1 120 ? 159.745 137.934 89.681  0.50 50.56  ? 66  TYR B CE1 1 
ATOM   3274  C CE1 B TYR B 1 120 ? 157.334 137.477 94.861  0.50 46.70  ? 66  TYR B CE1 1 
ATOM   3275  C CE2 A TYR B 1 120 ? 161.176 136.025 89.524  0.50 47.67  ? 66  TYR B CE2 1 
ATOM   3276  C CE2 B TYR B 1 120 ? 157.828 138.875 92.988  0.50 49.74  ? 66  TYR B CE2 1 
ATOM   3277  C CZ  A TYR B 1 120 ? 160.850 137.308 89.146  0.50 50.49  ? 66  TYR B CZ  1 
ATOM   3278  C CZ  B TYR B 1 120 ? 157.422 138.729 94.296  0.50 50.09  ? 66  TYR B CZ  1 
ATOM   3279  O OH  A TYR B 1 120 ? 161.626 137.966 88.221  0.50 53.15  ? 66  TYR B OH  1 
ATOM   3280  O OH  B TYR B 1 120 ? 157.097 139.841 95.038  0.50 55.61  ? 66  TYR B OH  1 
ATOM   3281  N N   . TRP B 1 121 ? 157.335 133.270 89.340  1.00 36.57  ? 67  TRP B N   1 
ATOM   3282  C CA  . TRP B 1 121 ? 157.804 132.222 88.439  1.00 38.13  ? 67  TRP B CA  1 
ATOM   3283  C C   . TRP B 1 121 ? 157.862 132.776 87.023  1.00 44.97  ? 67  TRP B C   1 
ATOM   3284  O O   . TRP B 1 121 ? 157.603 133.956 86.791  1.00 51.99  ? 67  TRP B O   1 
ATOM   3285  C CB  . TRP B 1 121 ? 156.927 130.968 88.535  1.00 34.81  ? 67  TRP B CB  1 
ATOM   3286  C CG  . TRP B 1 121 ? 155.570 131.097 87.933  1.00 32.58  ? 67  TRP B CG  1 
ATOM   3287  C CD1 . TRP B 1 121 ? 155.216 130.804 86.652  1.00 33.16  ? 67  TRP B CD1 1 
ATOM   3288  C CD2 . TRP B 1 121 ? 154.374 131.524 88.592  1.00 33.80  ? 67  TRP B CD2 1 
ATOM   3289  N NE1 . TRP B 1 121 ? 153.876 131.033 86.466  1.00 35.29  ? 67  TRP B NE1 1 
ATOM   3290  C CE2 . TRP B 1 121 ? 153.336 131.476 87.644  1.00 31.46  ? 67  TRP B CE2 1 
ATOM   3291  C CE3 . TRP B 1 121 ? 154.082 131.950 89.890  1.00 35.70  ? 67  TRP B CE3 1 
ATOM   3292  C CZ2 . TRP B 1 121 ? 152.028 131.837 87.951  1.00 30.08  ? 67  TRP B CZ2 1 
ATOM   3293  C CZ3 . TRP B 1 121 ? 152.784 132.307 90.194  1.00 34.51  ? 67  TRP B CZ3 1 
ATOM   3294  C CH2 . TRP B 1 121 ? 151.773 132.249 89.228  1.00 30.07  ? 67  TRP B CH2 1 
ATOM   3295  N N   . ARG B 1 122 ? 158.229 131.920 86.073  1.00 46.26  ? 68  ARG B N   1 
ATOM   3296  C CA  . ARG B 1 122 ? 158.346 132.324 84.678  1.00 52.00  ? 68  ARG B CA  1 
ATOM   3297  C C   . ARG B 1 122 ? 157.495 131.415 83.807  1.00 56.95  ? 68  ARG B C   1 
ATOM   3298  O O   . ARG B 1 122 ? 157.540 130.190 83.951  1.00 60.52  ? 68  ARG B O   1 
ATOM   3299  C CB  . ARG B 1 122 ? 159.803 132.296 84.200  1.00 54.82  ? 68  ARG B CB  1 
ATOM   3300  C CG  . ARG B 1 122 ? 159.973 132.756 82.758  1.00 59.97  ? 68  ARG B CG  1 
ATOM   3301  C CD  . ARG B 1 122 ? 161.435 132.877 82.352  1.00 72.56  ? 68  ARG B CD  1 
ATOM   3302  N NE  . ARG B 1 122 ? 161.574 133.437 81.012  1.00 91.93  ? 68  ARG B NE  1 
ATOM   3303  C CZ  . ARG B 1 122 ? 162.732 133.682 80.414  1.00 100.17 ? 68  ARG B CZ  1 
ATOM   3304  N NH1 . ARG B 1 122 ? 163.886 133.426 81.009  1.00 105.09 ? 68  ARG B NH1 1 
ATOM   3305  N NH2 . ARG B 1 122 ? 162.732 134.199 79.188  1.00 93.59  ? 68  ARG B NH2 1 
ATOM   3306  N N   . ASP B 1 123 ? 156.723 132.022 82.909  1.00 57.06  ? 69  ASP B N   1 
ATOM   3307  C CA  . ASP B 1 123 ? 155.922 131.303 81.920  1.00 54.65  ? 69  ASP B CA  1 
ATOM   3308  C C   . ASP B 1 123 ? 156.193 131.973 80.577  1.00 62.33  ? 69  ASP B C   1 
ATOM   3309  O O   . ASP B 1 123 ? 155.652 133.045 80.294  1.00 68.00  ? 69  ASP B O   1 
ATOM   3310  C CB  . ASP B 1 123 ? 154.439 131.334 82.279  1.00 54.83  ? 69  ASP B CB  1 
ATOM   3311  C CG  . ASP B 1 123 ? 153.623 130.324 81.492  1.00 59.85  ? 69  ASP B CG  1 
ATOM   3312  O OD1 . ASP B 1 123 ? 154.191 129.650 80.608  1.00 61.55  ? 69  ASP B OD1 1 
ATOM   3313  O OD2 . ASP B 1 123 ? 152.411 130.199 81.765  1.00 59.87  ? 69  ASP B OD2 1 
ATOM   3314  N N   . LYS B 1 124 ? 157.033 131.340 79.754  1.00 62.12  ? 70  LYS B N   1 
ATOM   3315  C CA  . LYS B 1 124 ? 157.454 131.958 78.501  1.00 60.82  ? 70  LYS B CA  1 
ATOM   3316  C C   . LYS B 1 124 ? 156.300 132.148 77.526  1.00 63.68  ? 70  LYS B C   1 
ATOM   3317  O O   . LYS B 1 124 ? 156.431 132.926 76.576  1.00 64.69  ? 70  LYS B O   1 
ATOM   3318  C CB  . LYS B 1 124 ? 158.561 131.129 77.853  1.00 60.45  ? 70  LYS B CB  1 
ATOM   3319  C CG  . LYS B 1 124 ? 159.891 131.217 78.580  1.00 71.73  ? 70  LYS B CG  1 
ATOM   3320  C CD  . LYS B 1 124 ? 160.971 130.435 77.857  1.00 79.65  ? 70  LYS B CD  1 
ATOM   3321  C CE  . LYS B 1 124 ? 162.318 130.595 78.541  1.00 86.64  ? 70  LYS B CE  1 
ATOM   3322  N NZ  . LYS B 1 124 ? 163.383 129.808 77.862  1.00 85.88  ? 70  LYS B NZ  1 
ATOM   3323  N N   . ARG B 1 125 ? 155.178 131.458 77.736  1.00 66.66  ? 71  ARG B N   1 
ATOM   3324  C CA  . ARG B 1 125 ? 153.992 131.711 76.928  1.00 62.06  ? 71  ARG B CA  1 
ATOM   3325  C C   . ARG B 1 125 ? 153.406 133.091 77.188  1.00 61.02  ? 71  ARG B C   1 
ATOM   3326  O O   . ARG B 1 125 ? 152.635 133.589 76.363  1.00 67.38  ? 71  ARG B O   1 
ATOM   3327  C CB  . ARG B 1 125 ? 152.933 130.645 77.198  1.00 58.23  ? 71  ARG B CB  1 
ATOM   3328  C CG  . ARG B 1 125 ? 153.385 129.231 76.902  1.00 62.59  ? 71  ARG B CG  1 
ATOM   3329  C CD  . ARG B 1 125 ? 152.369 128.230 77.409  1.00 63.97  ? 71  ARG B CD  1 
ATOM   3330  N NE  . ARG B 1 125 ? 152.201 128.325 78.854  1.00 61.42  ? 71  ARG B NE  1 
ATOM   3331  C CZ  . ARG B 1 125 ? 151.339 127.604 79.557  1.00 59.33  ? 71  ARG B CZ  1 
ATOM   3332  N NH1 . ARG B 1 125 ? 150.536 126.728 78.976  1.00 61.41  ? 71  ARG B NH1 1 
ATOM   3333  N NH2 . ARG B 1 125 ? 151.281 127.768 80.875  1.00 54.63  ? 71  ARG B NH2 1 
ATOM   3334  N N   . LEU B 1 126 ? 153.750 133.712 78.315  1.00 61.95  ? 72  LEU B N   1 
ATOM   3335  C CA  . LEU B 1 126 ? 153.270 135.043 78.677  1.00 66.19  ? 72  LEU B CA  1 
ATOM   3336  C C   . LEU B 1 126 ? 154.345 136.101 78.479  1.00 68.61  ? 72  LEU B C   1 
ATOM   3337  O O   . LEU B 1 126 ? 154.433 137.062 79.248  1.00 67.75  ? 72  LEU B O   1 
ATOM   3338  C CB  . LEU B 1 126 ? 152.772 135.047 80.119  1.00 61.42  ? 72  LEU B CB  1 
ATOM   3339  C CG  . LEU B 1 126 ? 151.663 134.048 80.447  1.00 54.63  ? 72  LEU B CG  1 
ATOM   3340  C CD1 . LEU B 1 126 ? 151.309 134.109 81.921  1.00 51.30  ? 72  LEU B CD1 1 
ATOM   3341  C CD2 . LEU B 1 126 ? 150.439 134.318 79.592  1.00 56.83  ? 72  LEU B CD2 1 
ATOM   3342  N N   . ALA B 1 127 ? 155.178 135.946 77.455  1.00 65.84  ? 73  ALA B N   1 
ATOM   3343  C CA  . ALA B 1 127 ? 156.255 136.883 77.170  1.00 66.44  ? 73  ALA B CA  1 
ATOM   3344  C C   . ALA B 1 127 ? 155.843 137.798 76.026  1.00 70.31  ? 73  ALA B C   1 
ATOM   3345  O O   . ALA B 1 127 ? 155.505 137.326 74.936  1.00 69.56  ? 73  ALA B O   1 
ATOM   3346  C CB  . ALA B 1 127 ? 157.544 136.141 76.818  1.00 58.76  ? 73  ALA B CB  1 
ATOM   3347  N N   . TYR B 1 128 ? 155.884 139.104 76.275  1.00 70.63  ? 74  TYR B N   1 
ATOM   3348  C CA  . TYR B 1 128 ? 155.470 140.104 75.306  1.00 70.09  ? 74  TYR B CA  1 
ATOM   3349  C C   . TYR B 1 128 ? 156.638 141.024 74.982  1.00 76.47  ? 74  TYR B C   1 
ATOM   3350  O O   . TYR B 1 128 ? 157.488 141.299 75.834  1.00 75.39  ? 74  TYR B O   1 
ATOM   3351  C CB  . TYR B 1 128 ? 154.279 140.924 75.823  1.00 68.57  ? 74  TYR B CB  1 
ATOM   3352  C CG  . TYR B 1 128 ? 154.526 141.624 77.141  1.00 63.67  ? 74  TYR B CG  1 
ATOM   3353  C CD1 . TYR B 1 128 ? 154.316 140.971 78.347  1.00 61.96  ? 74  TYR B CD1 1 
ATOM   3354  C CD2 . TYR B 1 128 ? 154.957 142.943 77.179  1.00 66.69  ? 74  TYR B CD2 1 
ATOM   3355  C CE1 . TYR B 1 128 ? 154.538 141.607 79.551  1.00 62.57  ? 74  TYR B CE1 1 
ATOM   3356  C CE2 . TYR B 1 128 ? 155.179 143.587 78.378  1.00 67.70  ? 74  TYR B CE2 1 
ATOM   3357  C CZ  . TYR B 1 128 ? 154.968 142.915 79.560  1.00 66.94  ? 74  TYR B CZ  1 
ATOM   3358  O OH  . TYR B 1 128 ? 155.189 143.555 80.756  1.00 70.49  ? 74  TYR B OH  1 
ATOM   3359  N N   . SER B 1 129 ? 156.672 141.495 73.738  1.00 78.13  ? 75  SER B N   1 
ATOM   3360  C CA  . SER B 1 129 ? 157.754 142.330 73.243  1.00 82.25  ? 75  SER B CA  1 
ATOM   3361  C C   . SER B 1 129 ? 157.200 143.640 72.699  1.00 88.68  ? 75  SER B C   1 
ATOM   3362  O O   . SER B 1 129 ? 156.096 143.688 72.150  1.00 87.86  ? 75  SER B O   1 
ATOM   3363  C CB  . SER B 1 129 ? 158.553 141.609 72.150  1.00 84.21  ? 75  SER B CB  1 
ATOM   3364  O OG  . SER B 1 129 ? 157.710 141.198 71.088  1.00 89.16  ? 75  SER B OG  1 
ATOM   3365  N N   . GLY B 1 130 ? 157.983 144.706 72.859  1.00 90.29  ? 76  GLY B N   1 
ATOM   3366  C CA  . GLY B 1 130 ? 157.635 146.018 72.372  1.00 95.96  ? 76  GLY B CA  1 
ATOM   3367  C C   . GLY B 1 130 ? 157.113 146.971 73.428  1.00 98.83  ? 76  GLY B C   1 
ATOM   3368  O O   . GLY B 1 130 ? 157.091 148.184 73.188  1.00 106.41 ? 76  GLY B O   1 
ATOM   3369  N N   . ILE B 1 131 ? 156.697 146.461 74.581  1.00 90.80  ? 77  ILE B N   1 
ATOM   3370  C CA  . ILE B 1 131 ? 156.170 147.277 75.668  1.00 86.63  ? 77  ILE B CA  1 
ATOM   3371  C C   . ILE B 1 131 ? 157.209 147.294 76.787  1.00 87.97  ? 77  ILE B C   1 
ATOM   3372  O O   . ILE B 1 131 ? 157.443 146.260 77.430  1.00 88.45  ? 77  ILE B O   1 
ATOM   3373  C CB  . ILE B 1 131 ? 154.821 146.749 76.171  1.00 81.95  ? 77  ILE B CB  1 
ATOM   3374  C CG1 . ILE B 1 131 ? 153.782 146.791 75.050  1.00 79.68  ? 77  ILE B CG1 1 
ATOM   3375  C CG2 . ILE B 1 131 ? 154.351 147.555 77.371  1.00 87.14  ? 77  ILE B CG2 1 
ATOM   3376  C CD1 . ILE B 1 131 ? 152.414 146.311 75.471  1.00 76.00  ? 77  ILE B CD1 1 
ATOM   3377  N N   . PRO B 1 132 ? 157.858 148.430 77.056  1.00 90.88  ? 78  PRO B N   1 
ATOM   3378  C CA  . PRO B 1 132 ? 158.819 148.538 78.160  1.00 93.06  ? 78  PRO B CA  1 
ATOM   3379  C C   . PRO B 1 132 ? 158.157 148.791 79.514  1.00 97.26  ? 78  PRO B C   1 
ATOM   3380  O O   . PRO B 1 132 ? 158.546 149.693 80.258  1.00 99.51  ? 78  PRO B O   1 
ATOM   3381  C CB  . PRO B 1 132 ? 159.694 149.718 77.729  1.00 92.32  ? 78  PRO B CB  1 
ATOM   3382  C CG  . PRO B 1 132 ? 158.763 150.587 76.958  1.00 90.61  ? 78  PRO B CG  1 
ATOM   3383  C CD  . PRO B 1 132 ? 157.802 149.663 76.251  1.00 93.41  ? 78  PRO B CD  1 
ATOM   3384  N N   . LEU B 1 133 ? 157.146 147.986 79.834  1.00 97.18  ? 79  LEU B N   1 
ATOM   3385  C CA  . LEU B 1 133 ? 156.384 148.147 81.063  1.00 93.57  ? 79  LEU B CA  1 
ATOM   3386  C C   . LEU B 1 133 ? 156.106 146.786 81.679  1.00 90.77  ? 79  LEU B C   1 
ATOM   3387  O O   . LEU B 1 133 ? 156.245 145.744 81.033  1.00 88.96  ? 79  LEU B O   1 
ATOM   3388  C CB  . LEU B 1 133 ? 155.055 148.875 80.818  1.00 86.78  ? 79  LEU B CB  1 
ATOM   3389  C CG  . LEU B 1 133 ? 155.098 150.353 80.439  1.00 92.56  ? 79  LEU B CG  1 
ATOM   3390  C CD1 . LEU B 1 133 ? 153.689 150.874 80.209  1.00 90.80  ? 79  LEU B CD1 1 
ATOM   3391  C CD2 . LEU B 1 133 ? 155.795 151.157 81.521  1.00 96.25  ? 79  LEU B CD2 1 
ATOM   3392  N N   . ASN B 1 134 ? 155.709 146.811 82.947  1.00 87.79  ? 80  ASN B N   1 
ATOM   3393  C CA  . ASN B 1 134 ? 155.199 145.638 83.642  1.00 75.65  ? 80  ASN B CA  1 
ATOM   3394  C C   . ASN B 1 134 ? 153.681 145.733 83.672  1.00 72.16  ? 80  ASN B C   1 
ATOM   3395  O O   . ASN B 1 134 ? 153.129 146.725 84.159  1.00 80.75  ? 80  ASN B O   1 
ATOM   3396  C CB  . ASN B 1 134 ? 155.769 145.549 85.056  1.00 74.28  ? 80  ASN B CB  1 
ATOM   3397  C CG  . ASN B 1 134 ? 157.267 145.356 85.066  1.00 81.85  ? 80  ASN B CG  1 
ATOM   3398  O OD1 . ASN B 1 134 ? 157.800 144.530 84.327  1.00 77.00  ? 80  ASN B OD1 1 
ATOM   3399  N ND2 . ASN B 1 134 ? 157.959 146.122 85.899  1.00 96.87  ? 80  ASN B ND2 1 
ATOM   3400  N N   . LEU B 1 135 ? 153.010 144.710 83.153  1.00 59.85  ? 81  LEU B N   1 
ATOM   3401  C CA  . LEU B 1 135 ? 151.562 144.744 82.985  1.00 57.35  ? 81  LEU B CA  1 
ATOM   3402  C C   . LEU B 1 135 ? 150.900 144.272 84.273  1.00 54.37  ? 81  LEU B C   1 
ATOM   3403  O O   . LEU B 1 135 ? 150.937 143.083 84.596  1.00 59.52  ? 81  LEU B O   1 
ATOM   3404  C CB  . LEU B 1 135 ? 151.135 143.879 81.802  1.00 53.12  ? 81  LEU B CB  1 
ATOM   3405  C CG  . LEU B 1 135 ? 151.721 144.249 80.439  1.00 58.33  ? 81  LEU B CG  1 
ATOM   3406  C CD1 . LEU B 1 135 ? 151.081 143.419 79.339  1.00 57.59  ? 81  LEU B CD1 1 
ATOM   3407  C CD2 . LEU B 1 135 ? 151.545 145.731 80.164  1.00 64.60  ? 81  LEU B CD2 1 
ATOM   3408  N N   . THR B 1 136 ? 150.296 145.201 85.010  1.00 50.67  ? 82  THR B N   1 
ATOM   3409  C CA  . THR B 1 136 ? 149.533 144.859 86.207  1.00 53.04  ? 82  THR B CA  1 
ATOM   3410  C C   . THR B 1 136 ? 148.108 144.564 85.763  1.00 51.27  ? 82  THR B C   1 
ATOM   3411  O O   . THR B 1 136 ? 147.304 145.477 85.568  1.00 58.45  ? 82  THR B O   1 
ATOM   3412  C CB  . THR B 1 136 ? 149.578 145.988 87.230  1.00 59.04  ? 82  THR B CB  1 
ATOM   3413  O OG1 . THR B 1 136 ? 150.938 146.255 87.590  1.00 62.92  ? 82  THR B OG1 1 
ATOM   3414  C CG2 . THR B 1 136 ? 148.798 145.601 88.477  1.00 59.24  ? 82  THR B CG2 1 
ATOM   3415  N N   . LEU B 1 137 ? 147.793 143.285 85.593  1.00 44.38  ? 83  LEU B N   1 
ATOM   3416  C CA  . LEU B 1 137 ? 146.504 142.931 85.028  1.00 47.54  ? 83  LEU B CA  1 
ATOM   3417  C C   . LEU B 1 137 ? 145.443 142.843 86.118  1.00 48.54  ? 83  LEU B C   1 
ATOM   3418  O O   . LEU B 1 137 ? 145.732 142.895 87.315  1.00 48.79  ? 83  LEU B O   1 
ATOM   3419  C CB  . LEU B 1 137 ? 146.597 141.614 84.260  1.00 48.69  ? 83  LEU B CB  1 
ATOM   3420  C CG  . LEU B 1 137 ? 147.545 141.598 83.062  1.00 46.90  ? 83  LEU B CG  1 
ATOM   3421  C CD1 . LEU B 1 137 ? 147.311 140.353 82.228  1.00 50.69  ? 83  LEU B CD1 1 
ATOM   3422  C CD2 . LEU B 1 137 ? 147.378 142.852 82.218  1.00 44.04  ? 83  LEU B CD2 1 
ATOM   3423  N N   . ASP B 1 138 ? 144.195 142.712 85.683  1.00 44.36  ? 84  ASP B N   1 
ATOM   3424  C CA  . ASP B 1 138 ? 143.087 142.593 86.614  1.00 48.68  ? 84  ASP B CA  1 
ATOM   3425  C C   . ASP B 1 138 ? 143.183 141.283 87.384  1.00 56.19  ? 84  ASP B C   1 
ATOM   3426  O O   . ASP B 1 138 ? 143.717 140.286 86.894  1.00 58.82  ? 84  ASP B O   1 
ATOM   3427  C CB  . ASP B 1 138 ? 141.757 142.667 85.868  1.00 49.48  ? 84  ASP B CB  1 
ATOM   3428  C CG  . ASP B 1 138 ? 140.616 143.109 86.756  1.00 60.32  ? 84  ASP B CG  1 
ATOM   3429  O OD1 . ASP B 1 138 ? 140.883 143.756 87.790  1.00 61.23  ? 84  ASP B OD1 1 
ATOM   3430  O OD2 . ASP B 1 138 ? 139.451 142.807 86.423  1.00 65.63  ? 84  ASP B OD2 1 
ATOM   3431  N N   . ASN B 1 139 ? 142.658 141.295 88.611  1.00 58.95  ? 85  ASN B N   1 
ATOM   3432  C CA  . ASN B 1 139 ? 142.714 140.104 89.451  1.00 53.52  ? 85  ASN B CA  1 
ATOM   3433  C C   . ASN B 1 139 ? 141.882 138.958 88.891  1.00 54.60  ? 85  ASN B C   1 
ATOM   3434  O O   . ASN B 1 139 ? 142.087 137.808 89.294  1.00 60.22  ? 85  ASN B O   1 
ATOM   3435  C CB  . ASN B 1 139 ? 142.253 140.439 90.870  1.00 51.97  ? 85  ASN B CB  1 
ATOM   3436  C CG  . ASN B 1 139 ? 140.820 140.927 90.917  1.00 59.09  ? 85  ASN B CG  1 
ATOM   3437  O OD1 . ASN B 1 139 ? 139.891 140.140 91.091  1.00 58.23  ? 85  ASN B OD1 1 
ATOM   3438  N ND2 . ASN B 1 139 ? 140.634 142.233 90.767  1.00 63.40  ? 85  ASN B ND2 1 
ATOM   3439  N N   . ARG B 1 140 ? 140.958 139.238 87.976  1.00 53.19  ? 86  ARG B N   1 
ATOM   3440  C CA  . ARG B 1 140 ? 140.143 138.194 87.371  1.00 58.45  ? 86  ARG B CA  1 
ATOM   3441  C C   . ARG B 1 140 ? 140.833 137.498 86.207  1.00 62.76  ? 86  ARG B C   1 
ATOM   3442  O O   . ARG B 1 140 ? 140.273 136.541 85.662  1.00 69.51  ? 86  ARG B O   1 
ATOM   3443  C CB  . ARG B 1 140 ? 138.806 138.775 86.910  1.00 58.92  ? 86  ARG B CB  1 
ATOM   3444  C CG  . ARG B 1 140 ? 137.836 139.042 88.046  1.00 63.69  ? 86  ARG B CG  1 
ATOM   3445  C CD  . ARG B 1 140 ? 136.652 139.866 87.583  1.00 60.23  ? 86  ARG B CD  1 
ATOM   3446  N NE  . ARG B 1 140 ? 137.044 141.229 87.248  1.00 63.61  ? 86  ARG B NE  1 
ATOM   3447  C CZ  . ARG B 1 140 ? 136.200 142.179 86.874  1.00 68.42  ? 86  ARG B CZ  1 
ATOM   3448  N NH1 . ARG B 1 140 ? 134.902 141.945 86.763  1.00 73.37  ? 86  ARG B NH1 1 
ATOM   3449  N NH2 . ARG B 1 140 ? 136.668 143.395 86.607  1.00 64.02  ? 86  ARG B NH2 1 
ATOM   3450  N N   . VAL B 1 141 ? 142.027 137.948 85.810  1.00 61.01  ? 87  VAL B N   1 
ATOM   3451  C CA  . VAL B 1 141 ? 142.770 137.253 84.761  1.00 58.61  ? 87  VAL B CA  1 
ATOM   3452  C C   . VAL B 1 141 ? 143.470 136.010 85.282  1.00 61.00  ? 87  VAL B C   1 
ATOM   3453  O O   . VAL B 1 141 ? 143.935 135.190 84.481  1.00 65.71  ? 87  VAL B O   1 
ATOM   3454  C CB  . VAL B 1 141 ? 143.798 138.189 84.096  1.00 47.51  ? 87  VAL B CB  1 
ATOM   3455  C CG1 . VAL B 1 141 ? 145.094 138.215 84.890  1.00 42.08  ? 87  VAL B CG1 1 
ATOM   3456  C CG2 . VAL B 1 141 ? 144.052 137.768 82.657  1.00 51.54  ? 87  VAL B CG2 1 
ATOM   3457  N N   . ALA B 1 142 ? 143.550 135.841 86.605  1.00 60.54  ? 88  ALA B N   1 
ATOM   3458  C CA  . ALA B 1 142 ? 144.160 134.645 87.171  1.00 54.96  ? 88  ALA B CA  1 
ATOM   3459  C C   . ALA B 1 142 ? 143.401 133.380 86.797  1.00 61.54  ? 88  ALA B C   1 
ATOM   3460  O O   . ALA B 1 142 ? 143.986 132.292 86.811  1.00 70.22  ? 88  ALA B O   1 
ATOM   3461  C CB  . ALA B 1 142 ? 144.252 134.769 88.691  1.00 48.31  ? 88  ALA B CB  1 
ATOM   3462  N N   . ASP B 1 143 ? 142.113 133.495 86.471  1.00 66.06  ? 89  ASP B N   1 
ATOM   3463  C CA  . ASP B 1 143 ? 141.349 132.347 86.001  1.00 70.27  ? 89  ASP B CA  1 
ATOM   3464  C C   . ASP B 1 143 ? 141.762 131.900 84.606  1.00 65.22  ? 89  ASP B C   1 
ATOM   3465  O O   . ASP B 1 143 ? 141.349 130.819 84.173  1.00 65.95  ? 89  ASP B O   1 
ATOM   3466  C CB  . ASP B 1 143 ? 139.855 132.672 86.016  1.00 74.55  ? 89  ASP B CB  1 
ATOM   3467  C CG  . ASP B 1 143 ? 139.349 133.023 87.401  1.00 85.47  ? 89  ASP B CG  1 
ATOM   3468  O OD1 . ASP B 1 143 ? 140.108 132.845 88.376  1.00 87.49  ? 89  ASP B OD1 1 
ATOM   3469  O OD2 . ASP B 1 143 ? 138.193 133.482 87.513  1.00 93.50  ? 89  ASP B OD2 1 
ATOM   3470  N N   . GLN B 1 144 ? 142.563 132.697 83.898  1.00 62.08  ? 90  GLN B N   1 
ATOM   3471  C CA  . GLN B 1 144 ? 142.974 132.392 82.534  1.00 61.62  ? 90  GLN B CA  1 
ATOM   3472  C C   . GLN B 1 144 ? 144.475 132.145 82.431  1.00 61.36  ? 90  GLN B C   1 
ATOM   3473  O O   . GLN B 1 144 ? 145.043 132.239 81.339  1.00 64.38  ? 90  GLN B O   1 
ATOM   3474  C CB  . GLN B 1 144 ? 142.553 133.521 81.595  1.00 65.11  ? 90  GLN B CB  1 
ATOM   3475  C CG  . GLN B 1 144 ? 141.072 133.848 81.668  1.00 74.31  ? 90  GLN B CG  1 
ATOM   3476  C CD  . GLN B 1 144 ? 140.739 135.196 81.067  1.00 83.49  ? 90  GLN B CD  1 
ATOM   3477  O OE1 . GLN B 1 144 ? 141.612 135.892 80.550  1.00 78.35  ? 90  GLN B OE1 1 
ATOM   3478  N NE2 . GLN B 1 144 ? 139.468 135.576 81.137  1.00 93.44  ? 90  GLN B NE2 1 
ATOM   3479  N N   . LEU B 1 145 ? 145.128 131.830 83.545  1.00 58.86  ? 91  LEU B N   1 
ATOM   3480  C CA  . LEU B 1 145 ? 146.552 131.543 83.573  1.00 56.01  ? 91  LEU B CA  1 
ATOM   3481  C C   . LEU B 1 145 ? 146.786 130.237 84.315  1.00 62.72  ? 91  LEU B C   1 
ATOM   3482  O O   . LEU B 1 145 ? 145.863 129.637 84.872  1.00 66.67  ? 91  LEU B O   1 
ATOM   3483  C CB  . LEU B 1 145 ? 147.345 132.672 84.246  1.00 53.04  ? 91  LEU B CB  1 
ATOM   3484  C CG  . LEU B 1 145 ? 147.196 134.086 83.688  1.00 54.97  ? 91  LEU B CG  1 
ATOM   3485  C CD1 . LEU B 1 145 ? 148.007 135.068 84.515  1.00 51.69  ? 91  LEU B CD1 1 
ATOM   3486  C CD2 . LEU B 1 145 ? 147.620 134.135 82.233  1.00 53.93  ? 91  LEU B CD2 1 
ATOM   3487  N N   . TRP B 1 146 ? 148.039 129.798 84.319  1.00 58.91  ? 92  TRP B N   1 
ATOM   3488  C CA  . TRP B 1 146 ? 148.455 128.675 85.145  1.00 49.63  ? 92  TRP B CA  1 
ATOM   3489  C C   . TRP B 1 146 ? 148.996 129.208 86.462  1.00 48.04  ? 92  TRP B C   1 
ATOM   3490  O O   . TRP B 1 146 ? 149.871 130.078 86.474  1.00 52.16  ? 92  TRP B O   1 
ATOM   3491  C CB  . TRP B 1 146 ? 149.518 127.833 84.439  1.00 45.68  ? 92  TRP B CB  1 
ATOM   3492  C CG  . TRP B 1 146 ? 150.034 126.700 85.279  1.00 46.26  ? 92  TRP B CG  1 
ATOM   3493  C CD1 . TRP B 1 146 ? 149.557 125.423 85.315  1.00 48.86  ? 92  TRP B CD1 1 
ATOM   3494  C CD2 . TRP B 1 146 ? 151.127 126.745 86.205  1.00 45.97  ? 92  TRP B CD2 1 
ATOM   3495  N NE1 . TRP B 1 146 ? 150.284 124.670 86.204  1.00 49.30  ? 92  TRP B NE1 1 
ATOM   3496  C CE2 . TRP B 1 146 ? 151.253 125.459 86.765  1.00 46.82  ? 92  TRP B CE2 1 
ATOM   3497  C CE3 . TRP B 1 146 ? 152.008 127.748 86.617  1.00 41.49  ? 92  TRP B CE3 1 
ATOM   3498  C CZ2 . TRP B 1 146 ? 152.226 125.150 87.710  1.00 41.00  ? 92  TRP B CZ2 1 
ATOM   3499  C CZ3 . TRP B 1 146 ? 152.971 127.440 87.554  1.00 40.65  ? 92  TRP B CZ3 1 
ATOM   3500  C CH2 . TRP B 1 146 ? 153.073 126.152 88.091  1.00 39.41  ? 92  TRP B CH2 1 
ATOM   3501  N N   . VAL B 1 147 ? 148.473 128.687 87.565  1.00 46.13  ? 93  VAL B N   1 
ATOM   3502  C CA  . VAL B 1 147 ? 148.931 129.086 88.891  1.00 38.43  ? 93  VAL B CA  1 
ATOM   3503  C C   . VAL B 1 147 ? 149.360 127.830 89.638  1.00 43.85  ? 93  VAL B C   1 
ATOM   3504  O O   . VAL B 1 147 ? 148.710 126.782 89.507  1.00 49.89  ? 93  VAL B O   1 
ATOM   3505  C CB  . VAL B 1 147 ? 147.842 129.860 89.651  1.00 38.50  ? 93  VAL B CB  1 
ATOM   3506  C CG1 . VAL B 1 147 ? 147.653 131.234 89.039  1.00 36.83  ? 93  VAL B CG1 1 
ATOM   3507  C CG2 . VAL B 1 147 ? 146.532 129.092 89.626  1.00 42.60  ? 93  VAL B CG2 1 
ATOM   3508  N N   . PRO B 1 148 ? 150.449 127.875 90.402  1.00 38.64  ? 94  PRO B N   1 
ATOM   3509  C CA  . PRO B 1 148 ? 150.896 126.676 91.116  1.00 40.27  ? 94  PRO B CA  1 
ATOM   3510  C C   . PRO B 1 148 ? 149.851 126.210 92.117  1.00 44.31  ? 94  PRO B C   1 
ATOM   3511  O O   . PRO B 1 148 ? 149.148 127.011 92.735  1.00 45.91  ? 94  PRO B O   1 
ATOM   3512  C CB  . PRO B 1 148 ? 152.177 127.137 91.820  1.00 33.42  ? 94  PRO B CB  1 
ATOM   3513  C CG  . PRO B 1 148 ? 152.620 128.342 91.062  1.00 31.83  ? 94  PRO B CG  1 
ATOM   3514  C CD  . PRO B 1 148 ? 151.366 129.008 90.598  1.00 34.38  ? 94  PRO B CD  1 
ATOM   3515  N N   . ASP B 1 149 ? 149.756 124.891 92.274  1.00 44.22  ? 95  ASP B N   1 
ATOM   3516  C CA  . ASP B 1 149 ? 148.830 124.319 93.241  1.00 45.78  ? 95  ASP B CA  1 
ATOM   3517  C C   . ASP B 1 149 ? 149.447 124.343 94.633  1.00 44.45  ? 95  ASP B C   1 
ATOM   3518  O O   . ASP B 1 149 ? 149.516 123.314 95.311  1.00 46.07  ? 95  ASP B O   1 
ATOM   3519  C CB  . ASP B 1 149 ? 148.444 122.894 92.844  1.00 51.43  ? 95  ASP B CB  1 
ATOM   3520  C CG  . ASP B 1 149 ? 149.649 122.026 92.545  1.00 54.42  ? 95  ASP B CG  1 
ATOM   3521  O OD1 . ASP B 1 149 ? 150.782 122.551 92.544  1.00 50.70  ? 95  ASP B OD1 1 
ATOM   3522  O OD2 . ASP B 1 149 ? 149.462 120.814 92.311  1.00 56.69  ? 95  ASP B OD2 1 
ATOM   3523  N N   . THR B 1 150 ? 149.898 125.518 95.057  1.00 39.62  ? 96  THR B N   1 
ATOM   3524  C CA  . THR B 1 150 ? 150.490 125.673 96.376  1.00 37.22  ? 96  THR B CA  1 
ATOM   3525  C C   . THR B 1 150 ? 149.419 125.566 97.451  1.00 36.75  ? 96  THR B C   1 
ATOM   3526  O O   . THR B 1 150 ? 148.368 126.205 97.360  1.00 43.53  ? 96  THR B O   1 
ATOM   3527  C CB  . THR B 1 150 ? 151.203 127.020 96.466  1.00 34.70  ? 96  THR B CB  1 
ATOM   3528  O OG1 . THR B 1 150 ? 152.444 126.953 95.755  1.00 37.51  ? 96  THR B OG1 1 
ATOM   3529  C CG2 . THR B 1 150 ? 151.461 127.399 97.909  1.00 32.79  ? 96  THR B CG2 1 
ATOM   3530  N N   . TYR B 1 151 ? 149.690 124.767 98.481  1.00 31.10  ? 97  TYR B N   1 
ATOM   3531  C CA  . TYR B 1 151 ? 148.768 124.622 99.593  1.00 33.51  ? 97  TYR B CA  1 
ATOM   3532  C C   . TYR B 1 151 ? 149.563 124.565 100.887 1.00 33.40  ? 97  TYR B C   1 
ATOM   3533  O O   . TYR B 1 151 ? 150.782 124.368 100.890 1.00 35.51  ? 97  TYR B O   1 
ATOM   3534  C CB  . TYR B 1 151 ? 147.878 123.383 99.434  1.00 35.53  ? 97  TYR B CB  1 
ATOM   3535  C CG  . TYR B 1 151 ? 148.529 122.084 99.842  1.00 33.14  ? 97  TYR B CG  1 
ATOM   3536  C CD1 . TYR B 1 151 ? 149.443 121.454 99.016  1.00 32.98  ? 97  TYR B CD1 1 
ATOM   3537  C CD2 . TYR B 1 151 ? 148.215 121.478 101.048 1.00 35.36  ? 97  TYR B CD2 1 
ATOM   3538  C CE1 . TYR B 1 151 ? 150.035 120.267 99.384  1.00 32.91  ? 97  TYR B CE1 1 
ATOM   3539  C CE2 . TYR B 1 151 ? 148.799 120.289 101.422 1.00 36.12  ? 97  TYR B CE2 1 
ATOM   3540  C CZ  . TYR B 1 151 ? 149.709 119.688 100.587 1.00 33.80  ? 97  TYR B CZ  1 
ATOM   3541  O OH  . TYR B 1 151 ? 150.297 118.503 100.955 1.00 41.78  ? 97  TYR B OH  1 
ATOM   3542  N N   . PHE B 1 152 ? 148.860 124.765 101.996 1.00 30.76  ? 98  PHE B N   1 
ATOM   3543  C CA  . PHE B 1 152 ? 149.464 124.765 103.321 1.00 28.90  ? 98  PHE B CA  1 
ATOM   3544  C C   . PHE B 1 152 ? 149.182 123.425 103.983 1.00 35.35  ? 98  PHE B C   1 
ATOM   3545  O O   . PHE B 1 152 ? 148.022 123.071 104.216 1.00 41.21  ? 98  PHE B O   1 
ATOM   3546  C CB  . PHE B 1 152 ? 148.934 125.927 104.154 1.00 32.19  ? 98  PHE B CB  1 
ATOM   3547  C CG  . PHE B 1 152 ? 149.048 127.248 103.460 1.00 38.24  ? 98  PHE B CG  1 
ATOM   3548  C CD1 . PHE B 1 152 ? 150.266 127.897 103.379 1.00 34.11  ? 98  PHE B CD1 1 
ATOM   3549  C CD2 . PHE B 1 152 ? 147.946 127.826 102.860 1.00 44.76  ? 98  PHE B CD2 1 
ATOM   3550  C CE1 . PHE B 1 152 ? 150.379 129.104 102.728 1.00 31.58  ? 98  PHE B CE1 1 
ATOM   3551  C CE2 . PHE B 1 152 ? 148.053 129.033 102.209 1.00 41.10  ? 98  PHE B CE2 1 
ATOM   3552  C CZ  . PHE B 1 152 ? 149.270 129.673 102.142 1.00 38.87  ? 98  PHE B CZ  1 
ATOM   3553  N N   . LEU B 1 153 ? 150.249 122.686 104.281 1.00 37.60  ? 99  LEU B N   1 
ATOM   3554  C CA  . LEU B 1 153 ? 150.106 121.285 104.653 1.00 34.86  ? 99  LEU B CA  1 
ATOM   3555  C C   . LEU B 1 153 ? 149.476 121.112 106.028 1.00 39.38  ? 99  LEU B C   1 
ATOM   3556  O O   . LEU B 1 153 ? 148.780 120.117 106.264 1.00 52.10  ? 99  LEU B O   1 
ATOM   3557  C CB  . LEU B 1 153 ? 151.473 120.604 104.592 1.00 39.23  ? 99  LEU B CB  1 
ATOM   3558  C CG  . LEU B 1 153 ? 151.559 119.122 104.942 1.00 48.63  ? 99  LEU B CG  1 
ATOM   3559  C CD1 . LEU B 1 153 ? 152.410 118.395 103.920 1.00 51.15  ? 99  LEU B CD1 1 
ATOM   3560  C CD2 . LEU B 1 153 ? 152.137 118.949 106.335 1.00 50.34  ? 99  LEU B CD2 1 
ATOM   3561  N N   . ASN B 1 154 ? 149.691 122.057 106.940 1.00 38.32  ? 100 ASN B N   1 
ATOM   3562  C CA  . ASN B 1 154 ? 149.232 121.915 108.314 1.00 37.91  ? 100 ASN B CA  1 
ATOM   3563  C C   . ASN B 1 154 ? 148.032 122.790 108.651 1.00 39.55  ? 100 ASN B C   1 
ATOM   3564  O O   . ASN B 1 154 ? 147.599 122.795 109.806 1.00 43.18  ? 100 ASN B O   1 
ATOM   3565  C CB  . ASN B 1 154 ? 150.376 122.224 109.284 1.00 39.51  ? 100 ASN B CB  1 
ATOM   3566  C CG  . ASN B 1 154 ? 150.910 123.631 109.125 1.00 43.64  ? 100 ASN B CG  1 
ATOM   3567  O OD1 . ASN B 1 154 ? 150.942 124.174 108.022 1.00 44.85  ? 100 ASN B OD1 1 
ATOM   3568  N ND2 . ASN B 1 154 ? 151.335 124.230 110.231 1.00 49.39  ? 100 ASN B ND2 1 
ATOM   3569  N N   . ASP B 1 155 ? 147.481 123.521 107.686 1.00 43.76  ? 101 ASP B N   1 
ATOM   3570  C CA  . ASP B 1 155 ? 146.351 124.389 107.978 1.00 40.02  ? 101 ASP B CA  1 
ATOM   3571  C C   . ASP B 1 155 ? 145.077 123.570 108.170 1.00 45.05  ? 101 ASP B C   1 
ATOM   3572  O O   . ASP B 1 155 ? 144.987 122.405 107.775 1.00 51.58  ? 101 ASP B O   1 
ATOM   3573  C CB  . ASP B 1 155 ? 146.149 125.415 106.863 1.00 40.21  ? 101 ASP B CB  1 
ATOM   3574  C CG  . ASP B 1 155 ? 145.299 124.884 105.727 1.00 52.71  ? 101 ASP B CG  1 
ATOM   3575  O OD1 . ASP B 1 155 ? 145.552 123.754 105.262 1.00 60.35  ? 101 ASP B OD1 1 
ATOM   3576  O OD2 . ASP B 1 155 ? 144.368 125.597 105.300 1.00 55.56  ? 101 ASP B OD2 1 
ATOM   3577  N N   . LYS B 1 156 ? 144.081 124.202 108.778 1.00 44.51  ? 102 LYS B N   1 
ATOM   3578  C CA  . LYS B 1 156 ? 142.798 123.578 109.067 1.00 43.46  ? 102 LYS B CA  1 
ATOM   3579  C C   . LYS B 1 156 ? 141.639 124.253 108.359 1.00 48.37  ? 102 LYS B C   1 
ATOM   3580  O O   . LYS B 1 156 ? 140.715 123.571 107.911 1.00 58.67  ? 102 LYS B O   1 
ATOM   3581  C CB  . LYS B 1 156 ? 142.553 123.586 110.581 1.00 41.96  ? 102 LYS B CB  1 
ATOM   3582  C CG  . LYS B 1 156 ? 143.689 122.968 111.376 1.00 45.55  ? 102 LYS B CG  1 
ATOM   3583  C CD  . LYS B 1 156 ? 143.660 123.396 112.829 1.00 38.85  ? 102 LYS B CD  1 
ATOM   3584  C CE  . LYS B 1 156 ? 142.407 122.907 113.527 1.00 41.13  ? 102 LYS B CE  1 
ATOM   3585  N NZ  . LYS B 1 156 ? 142.411 123.295 114.962 1.00 44.65  ? 102 LYS B NZ  1 
ATOM   3586  N N   . LYS B 1 157 ? 141.666 125.579 108.244 1.00 45.83  ? 103 LYS B N   1 
ATOM   3587  C CA  . LYS B 1 157 ? 140.640 126.309 107.506 1.00 47.08  ? 103 LYS B CA  1 
ATOM   3588  C C   . LYS B 1 157 ? 141.208 127.667 107.132 1.00 46.66  ? 103 LYS B C   1 
ATOM   3589  O O   . LYS B 1 157 ? 141.527 128.467 108.017 1.00 50.60  ? 103 LYS B O   1 
ATOM   3590  C CB  . LYS B 1 157 ? 139.367 126.458 108.338 1.00 50.49  ? 103 LYS B CB  1 
ATOM   3591  C CG  . LYS B 1 157 ? 138.115 126.644 107.506 1.00 52.69  ? 103 LYS B CG  1 
ATOM   3592  C CD  . LYS B 1 157 ? 136.877 126.199 108.260 1.00 63.90  ? 103 LYS B CD  1 
ATOM   3593  C CE  . LYS B 1 157 ? 135.678 126.121 107.331 1.00 83.21  ? 103 LYS B CE  1 
ATOM   3594  N NZ  . LYS B 1 157 ? 134.476 125.563 108.006 1.00 93.96  ? 103 LYS B NZ  1 
ATOM   3595  N N   . SER B 1 158 ? 141.340 127.923 105.834 1.00 41.56  ? 104 SER B N   1 
ATOM   3596  C CA  . SER B 1 158 ? 141.907 129.165 105.334 1.00 44.15  ? 104 SER B CA  1 
ATOM   3597  C C   . SER B 1 158 ? 141.048 129.698 104.197 1.00 39.79  ? 104 SER B C   1 
ATOM   3598  O O   . SER B 1 158 ? 140.280 128.962 103.574 1.00 44.55  ? 104 SER B O   1 
ATOM   3599  C CB  . SER B 1 158 ? 143.351 128.970 104.856 1.00 48.29  ? 104 SER B CB  1 
ATOM   3600  O OG  . SER B 1 158 ? 143.424 127.976 103.852 1.00 59.45  ? 104 SER B OG  1 
ATOM   3601  N N   . PHE B 1 159 ? 141.186 130.994 103.934 1.00 38.71  ? 105 PHE B N   1 
ATOM   3602  C CA  . PHE B 1 159 ? 140.421 131.631 102.873 1.00 38.50  ? 105 PHE B CA  1 
ATOM   3603  C C   . PHE B 1 159 ? 141.170 132.860 102.385 1.00 34.54  ? 105 PHE B C   1 
ATOM   3604  O O   . PHE B 1 159 ? 142.089 133.355 103.041 1.00 39.77  ? 105 PHE B O   1 
ATOM   3605  C CB  . PHE B 1 159 ? 139.012 132.012 103.342 1.00 35.80  ? 105 PHE B CB  1 
ATOM   3606  C CG  . PHE B 1 159 ? 138.993 133.011 104.463 1.00 36.88  ? 105 PHE B CG  1 
ATOM   3607  C CD1 . PHE B 1 159 ? 139.070 132.595 105.780 1.00 40.82  ? 105 PHE B CD1 1 
ATOM   3608  C CD2 . PHE B 1 159 ? 138.888 134.366 104.201 1.00 35.55  ? 105 PHE B CD2 1 
ATOM   3609  C CE1 . PHE B 1 159 ? 139.050 133.509 106.811 1.00 38.31  ? 105 PHE B CE1 1 
ATOM   3610  C CE2 . PHE B 1 159 ? 138.871 135.285 105.228 1.00 36.40  ? 105 PHE B CE2 1 
ATOM   3611  C CZ  . PHE B 1 159 ? 138.950 134.856 106.535 1.00 35.94  ? 105 PHE B CZ  1 
ATOM   3612  N N   . VAL B 1 160 ? 140.758 133.344 101.217 1.00 29.67  ? 106 VAL B N   1 
ATOM   3613  C CA  . VAL B 1 160 ? 141.304 134.552 100.611 1.00 33.63  ? 106 VAL B CA  1 
ATOM   3614  C C   . VAL B 1 160 ? 140.270 135.659 100.754 1.00 38.01  ? 106 VAL B C   1 
ATOM   3615  O O   . VAL B 1 160 ? 139.098 135.469 100.409 1.00 43.77  ? 106 VAL B O   1 
ATOM   3616  C CB  . VAL B 1 160 ? 141.670 134.325 99.134  1.00 31.44  ? 106 VAL B CB  1 
ATOM   3617  C CG1 . VAL B 1 160 ? 142.252 135.588 98.533  1.00 33.02  ? 106 VAL B CG1 1 
ATOM   3618  C CG2 . VAL B 1 160 ? 142.647 133.173 99.008  1.00 30.01  ? 106 VAL B CG2 1 
ATOM   3619  N N   . HIS B 1 161 ? 140.702 136.807 101.268 1.00 31.51  ? 107 HIS B N   1 
ATOM   3620  C CA  . HIS B 1 161 ? 139.791 137.920 101.493 1.00 37.07  ? 107 HIS B CA  1 
ATOM   3621  C C   . HIS B 1 161 ? 139.248 138.444 100.169 1.00 43.85  ? 107 HIS B C   1 
ATOM   3622  O O   . HIS B 1 161 ? 139.973 138.538 99.176  1.00 43.10  ? 107 HIS B O   1 
ATOM   3623  C CB  . HIS B 1 161 ? 140.501 139.034 102.254 1.00 33.23  ? 107 HIS B CB  1 
ATOM   3624  C CG  . HIS B 1 161 ? 141.039 138.611 103.585 1.00 31.70  ? 107 HIS B CG  1 
ATOM   3625  N ND1 . HIS B 1 161 ? 140.440 138.961 104.775 1.00 36.38  ? 107 HIS B ND1 1 
ATOM   3626  C CD2 . HIS B 1 161 ? 142.120 137.865 103.914 1.00 35.34  ? 107 HIS B CD2 1 
ATOM   3627  C CE1 . HIS B 1 161 ? 141.128 138.452 105.780 1.00 34.40  ? 107 HIS B CE1 1 
ATOM   3628  N NE2 . HIS B 1 161 ? 142.152 137.781 105.285 1.00 37.28  ? 107 HIS B NE2 1 
ATOM   3629  N N   . GLY B 1 162 ? 137.961 138.790 100.159 1.00 43.54  ? 108 GLY B N   1 
ATOM   3630  C CA  . GLY B 1 162 ? 137.298 139.170 98.928  1.00 44.30  ? 108 GLY B CA  1 
ATOM   3631  C C   . GLY B 1 162 ? 136.497 140.456 98.978  1.00 48.12  ? 108 GLY B C   1 
ATOM   3632  O O   . GLY B 1 162 ? 135.430 140.545 98.365  1.00 55.06  ? 108 GLY B O   1 
ATOM   3633  N N   . VAL B 1 163 ? 136.991 141.459 99.699  1.00 43.76  ? 109 VAL B N   1 
ATOM   3634  C CA  . VAL B 1 163 ? 136.342 142.763 99.791  1.00 41.02  ? 109 VAL B CA  1 
ATOM   3635  C C   . VAL B 1 163 ? 137.395 143.835 99.550  1.00 40.31  ? 109 VAL B C   1 
ATOM   3636  O O   . VAL B 1 163 ? 138.445 143.830 100.201 1.00 40.45  ? 109 VAL B O   1 
ATOM   3637  C CB  . VAL B 1 163 ? 135.657 142.964 101.157 1.00 45.73  ? 109 VAL B CB  1 
ATOM   3638  C CG1 . VAL B 1 163 ? 135.239 144.410 101.343 1.00 45.27  ? 109 VAL B CG1 1 
ATOM   3639  C CG2 . VAL B 1 163 ? 134.453 142.049 101.280 1.00 46.63  ? 109 VAL B CG2 1 
ATOM   3640  N N   . THR B 1 164 ? 137.120 144.757 98.626  1.00 38.06  ? 110 THR B N   1 
ATOM   3641  C CA  . THR B 1 164 ? 135.870 144.816 97.867  1.00 38.43  ? 110 THR B CA  1 
ATOM   3642  C C   . THR B 1 164 ? 135.809 143.770 96.759  1.00 48.82  ? 110 THR B C   1 
ATOM   3643  O O   . THR B 1 164 ? 134.748 143.221 96.465  1.00 54.50  ? 110 THR B O   1 
ATOM   3644  C CB  . THR B 1 164 ? 135.673 146.205 97.243  1.00 34.95  ? 110 THR B CB  1 
ATOM   3645  O OG1 . THR B 1 164 ? 136.731 146.462 96.314  1.00 37.33  ? 110 THR B OG1 1 
ATOM   3646  C CG2 . THR B 1 164 ? 135.690 147.273 98.320  1.00 37.20  ? 110 THR B CG2 1 
ATOM   3647  N N   . VAL B 1 165 ? 136.959 143.504 96.147  1.00 46.32  ? 111 VAL B N   1 
ATOM   3648  C CA  . VAL B 1 165 ? 137.099 142.415 95.189  1.00 44.60  ? 111 VAL B CA  1 
ATOM   3649  C C   . VAL B 1 165 ? 138.045 141.394 95.799  1.00 43.88  ? 111 VAL B C   1 
ATOM   3650  O O   . VAL B 1 165 ? 138.567 141.604 96.899  1.00 47.19  ? 111 VAL B O   1 
ATOM   3651  C CB  . VAL B 1 165 ? 137.617 142.915 93.830  1.00 42.45  ? 111 VAL B CB  1 
ATOM   3652  C CG1 . VAL B 1 165 ? 136.730 144.030 93.307  1.00 39.21  ? 111 VAL B CG1 1 
ATOM   3653  C CG2 . VAL B 1 165 ? 139.054 143.382 93.953  1.00 40.56  ? 111 VAL B CG2 1 
ATOM   3654  N N   . LYS B 1 166 ? 138.262 140.279 95.105  1.00 44.91  ? 112 LYS B N   1 
ATOM   3655  C CA  . LYS B 1 166 ? 139.211 139.286 95.589  1.00 43.36  ? 112 LYS B CA  1 
ATOM   3656  C C   . LYS B 1 166 ? 140.590 139.911 95.738  1.00 48.13  ? 112 LYS B C   1 
ATOM   3657  O O   . LYS B 1 166 ? 141.104 140.541 94.810  1.00 51.95  ? 112 LYS B O   1 
ATOM   3658  C CB  . LYS B 1 166 ? 139.275 138.094 94.636  1.00 48.76  ? 112 LYS B CB  1 
ATOM   3659  C CG  . LYS B 1 166 ? 138.206 137.049 94.871  1.00 55.97  ? 112 LYS B CG  1 
ATOM   3660  C CD  . LYS B 1 166 ? 138.483 135.803 94.052  1.00 63.66  ? 112 LYS B CD  1 
ATOM   3661  C CE  . LYS B 1 166 ? 139.834 135.206 94.406  1.00 60.27  ? 112 LYS B CE  1 
ATOM   3662  N NZ  . LYS B 1 166 ? 139.909 134.842 95.846  1.00 56.88  ? 112 LYS B NZ  1 
ATOM   3663  N N   . ASN B 1 167 ? 141.188 139.734 96.913  1.00 41.96  ? 113 ASN B N   1 
ATOM   3664  C CA  . ASN B 1 167 ? 142.510 140.285 97.194  1.00 34.39  ? 113 ASN B CA  1 
ATOM   3665  C C   . ASN B 1 167 ? 143.525 139.436 96.447  1.00 37.63  ? 113 ASN B C   1 
ATOM   3666  O O   . ASN B 1 167 ? 144.034 138.436 96.954  1.00 39.26  ? 113 ASN B O   1 
ATOM   3667  C CB  . ASN B 1 167 ? 142.783 140.315 98.691  1.00 31.81  ? 113 ASN B CB  1 
ATOM   3668  C CG  . ASN B 1 167 ? 141.891 141.293 99.423  1.00 36.75  ? 113 ASN B CG  1 
ATOM   3669  O OD1 . ASN B 1 167 ? 141.895 141.353 100.651 1.00 42.96  ? 113 ASN B OD1 1 
ATOM   3670  N ND2 . ASN B 1 167 ? 141.116 142.065 98.671  1.00 37.41  ? 113 ASN B ND2 1 
ATOM   3671  N N   . ARG B 1 168 ? 143.819 139.848 95.219  1.00 40.06  ? 114 ARG B N   1 
ATOM   3672  C CA  . ARG B 1 168 ? 144.640 139.057 94.320  1.00 37.12  ? 114 ARG B CA  1 
ATOM   3673  C C   . ARG B 1 168 ? 145.327 139.994 93.342  1.00 42.29  ? 114 ARG B C   1 
ATOM   3674  O O   . ARG B 1 168 ? 144.725 140.961 92.871  1.00 53.24  ? 114 ARG B O   1 
ATOM   3675  C CB  . ARG B 1 168 ? 143.790 138.023 93.579  1.00 37.38  ? 114 ARG B CB  1 
ATOM   3676  C CG  . ARG B 1 168 ? 144.572 137.076 92.706  1.00 41.70  ? 114 ARG B CG  1 
ATOM   3677  C CD  . ARG B 1 168 ? 143.710 135.894 92.326  1.00 46.51  ? 114 ARG B CD  1 
ATOM   3678  N NE  . ARG B 1 168 ? 142.498 136.308 91.632  1.00 55.23  ? 114 ARG B NE  1 
ATOM   3679  C CZ  . ARG B 1 168 ? 141.516 135.486 91.290  1.00 60.63  ? 114 ARG B CZ  1 
ATOM   3680  N NH1 . ARG B 1 168 ? 141.563 134.196 91.581  1.00 62.37  ? 114 ARG B NH1 1 
ATOM   3681  N NH2 . ARG B 1 168 ? 140.462 135.969 90.639  1.00 63.39  ? 114 ARG B NH2 1 
ATOM   3682  N N   . MET B 1 169 ? 146.591 139.708 93.055  1.00 34.50  ? 115 MET B N   1 
ATOM   3683  C CA  . MET B 1 169 ? 147.407 140.553 92.197  1.00 34.60  ? 115 MET B CA  1 
ATOM   3684  C C   . MET B 1 169 ? 148.116 139.693 91.166  1.00 40.45  ? 115 MET B C   1 
ATOM   3685  O O   . MET B 1 169 ? 148.760 138.703 91.522  1.00 48.04  ? 115 MET B O   1 
ATOM   3686  C CB  . MET B 1 169 ? 148.430 141.342 93.016  1.00 35.76  ? 115 MET B CB  1 
ATOM   3687  C CG  . MET B 1 169 ? 149.618 141.829 92.213  1.00 39.27  ? 115 MET B CG  1 
ATOM   3688  S SD  . MET B 1 169 ? 150.840 142.676 93.228  1.00 71.69  ? 115 MET B SD  1 
ATOM   3689  C CE  . MET B 1 169 ? 151.233 141.397 94.416  1.00 54.59  ? 115 MET B CE  1 
ATOM   3690  N N   . ILE B 1 170 ? 148.005 140.080 89.898  1.00 39.19  ? 116 ILE B N   1 
ATOM   3691  C CA  . ILE B 1 170 ? 148.715 139.435 88.801  1.00 34.63  ? 116 ILE B CA  1 
ATOM   3692  C C   . ILE B 1 170 ? 149.536 140.498 88.089  1.00 41.00  ? 116 ILE B C   1 
ATOM   3693  O O   . ILE B 1 170 ? 148.989 141.507 87.622  1.00 51.17  ? 116 ILE B O   1 
ATOM   3694  C CB  . ILE B 1 170 ? 147.757 138.735 87.826  1.00 34.30  ? 116 ILE B CB  1 
ATOM   3695  C CG1 . ILE B 1 170 ? 147.393 137.344 88.340  1.00 36.35  ? 116 ILE B CG1 1 
ATOM   3696  C CG2 . ILE B 1 170 ? 148.386 138.626 86.446  1.00 39.34  ? 116 ILE B CG2 1 
ATOM   3697  C CD1 . ILE B 1 170 ? 148.519 136.344 88.207  1.00 36.07  ? 116 ILE B CD1 1 
ATOM   3698  N N   . ARG B 1 171 ? 150.846 140.280 88.015  1.00 35.91  ? 117 ARG B N   1 
ATOM   3699  C CA  . ARG B 1 171 ? 151.743 141.193 87.324  1.00 38.13  ? 117 ARG B CA  1 
ATOM   3700  C C   . ARG B 1 171 ? 152.616 140.405 86.363  1.00 41.83  ? 117 ARG B C   1 
ATOM   3701  O O   . ARG B 1 171 ? 153.237 139.413 86.754  1.00 49.87  ? 117 ARG B O   1 
ATOM   3702  C CB  . ARG B 1 171 ? 152.607 141.974 88.312  1.00 40.52  ? 117 ARG B CB  1 
ATOM   3703  C CG  . ARG B 1 171 ? 153.447 143.060 87.671  1.00 49.31  ? 117 ARG B CG  1 
ATOM   3704  C CD  . ARG B 1 171 ? 154.217 143.831 88.722  1.00 47.43  ? 117 ARG B CD  1 
ATOM   3705  N NE  . ARG B 1 171 ? 153.325 144.485 89.670  1.00 48.50  ? 117 ARG B NE  1 
ATOM   3706  C CZ  . ARG B 1 171 ? 153.727 145.105 90.770  1.00 50.05  ? 117 ARG B CZ  1 
ATOM   3707  N NH1 . ARG B 1 171 ? 155.006 145.160 91.103  1.00 55.44  ? 117 ARG B NH1 1 
ATOM   3708  N NH2 . ARG B 1 171 ? 152.823 145.682 91.557  1.00 45.55  ? 117 ARG B NH2 1 
ATOM   3709  N N   . LEU B 1 172 ? 152.665 140.851 85.114  1.00 44.51  ? 118 LEU B N   1 
ATOM   3710  C CA  . LEU B 1 172 ? 153.487 140.241 84.083  1.00 44.68  ? 118 LEU B CA  1 
ATOM   3711  C C   . LEU B 1 172 ? 154.666 141.148 83.758  1.00 53.59  ? 118 LEU B C   1 
ATOM   3712  O O   . LEU B 1 172 ? 154.597 142.370 83.923  1.00 65.75  ? 118 LEU B O   1 
ATOM   3713  C CB  . LEU B 1 172 ? 152.675 139.973 82.815  1.00 43.83  ? 118 LEU B CB  1 
ATOM   3714  C CG  . LEU B 1 172 ? 151.336 139.260 82.998  1.00 37.17  ? 118 LEU B CG  1 
ATOM   3715  C CD1 . LEU B 1 172 ? 150.693 138.989 81.651  1.00 38.75  ? 118 LEU B CD1 1 
ATOM   3716  C CD2 . LEU B 1 172 ? 151.520 137.970 83.773  1.00 43.12  ? 118 LEU B CD2 1 
ATOM   3717  N N   . HIS B 1 173 ? 155.737 140.536 83.276  1.00 48.97  ? 119 HIS B N   1 
ATOM   3718  C CA  . HIS B 1 173 ? 156.987 141.205 82.962  1.00 57.92  ? 119 HIS B CA  1 
ATOM   3719  C C   . HIS B 1 173 ? 157.365 140.906 81.520  1.00 65.29  ? 119 HIS B C   1 
ATOM   3720  O O   . HIS B 1 173 ? 156.900 139.918 80.942  1.00 67.67  ? 119 HIS B O   1 
ATOM   3721  C CB  . HIS B 1 173 ? 158.107 140.750 83.911  1.00 58.79  ? 119 HIS B CB  1 
ATOM   3722  C CG  . HIS B 1 173 ? 157.870 141.120 85.342  1.00 61.02  ? 119 HIS B CG  1 
ATOM   3723  N ND1 . HIS B 1 173 ? 156.872 140.551 86.102  1.00 54.57  ? 119 HIS B ND1 1 
ATOM   3724  C CD2 . HIS B 1 173 ? 158.500 142.005 86.150  1.00 64.51  ? 119 HIS B CD2 1 
ATOM   3725  C CE1 . HIS B 1 173 ? 156.898 141.066 87.318  1.00 49.48  ? 119 HIS B CE1 1 
ATOM   3726  N NE2 . HIS B 1 173 ? 157.876 141.951 87.374  1.00 58.35  ? 119 HIS B NE2 1 
ATOM   3727  N N   . PRO B 1 174 ? 158.196 141.753 80.905  1.00 67.68  ? 120 PRO B N   1 
ATOM   3728  C CA  . PRO B 1 174 ? 158.528 141.552 79.483  1.00 66.81  ? 120 PRO B CA  1 
ATOM   3729  C C   . PRO B 1 174 ? 159.142 140.197 79.172  1.00 67.42  ? 120 PRO B C   1 
ATOM   3730  O O   . PRO B 1 174 ? 158.926 139.672 78.073  1.00 65.98  ? 120 PRO B O   1 
ATOM   3731  C CB  . PRO B 1 174 ? 159.511 142.694 79.195  1.00 63.53  ? 120 PRO B CB  1 
ATOM   3732  C CG  . PRO B 1 174 ? 159.143 143.751 80.172  1.00 63.35  ? 120 PRO B CG  1 
ATOM   3733  C CD  . PRO B 1 174 ? 158.724 143.030 81.418  1.00 65.92  ? 120 PRO B CD  1 
ATOM   3734  N N   . ASP B 1 175 ? 159.899 139.613 80.100  1.00 69.02  ? 121 ASP B N   1 
ATOM   3735  C CA  . ASP B 1 175 ? 160.536 138.321 79.886  1.00 72.33  ? 121 ASP B CA  1 
ATOM   3736  C C   . ASP B 1 175 ? 159.630 137.149 80.250  1.00 75.99  ? 121 ASP B C   1 
ATOM   3737  O O   . ASP B 1 175 ? 160.131 136.057 80.541  1.00 78.73  ? 121 ASP B O   1 
ATOM   3738  C CB  . ASP B 1 175 ? 161.845 138.241 80.675  1.00 74.39  ? 121 ASP B CB  1 
ATOM   3739  C CG  . ASP B 1 175 ? 161.653 138.505 82.154  1.00 80.23  ? 121 ASP B CG  1 
ATOM   3740  O OD1 . ASP B 1 175 ? 160.538 138.903 82.550  1.00 75.65  ? 121 ASP B OD1 1 
ATOM   3741  O OD2 . ASP B 1 175 ? 162.618 138.312 82.922  1.00 91.03  ? 121 ASP B OD2 1 
ATOM   3742  N N   . GLY B 1 176 ? 158.317 137.350 80.241  1.00 70.56  ? 122 GLY B N   1 
ATOM   3743  C CA  . GLY B 1 176 ? 157.386 136.282 80.560  1.00 64.08  ? 122 GLY B CA  1 
ATOM   3744  C C   . GLY B 1 176 ? 157.454 135.807 81.995  1.00 61.46  ? 122 GLY B C   1 
ATOM   3745  O O   . GLY B 1 176 ? 157.399 134.598 82.248  1.00 62.78  ? 122 GLY B O   1 
ATOM   3746  N N   . THR B 1 177 ? 157.563 136.731 82.942  1.00 58.27  ? 123 THR B N   1 
ATOM   3747  C CA  . THR B 1 177 ? 157.685 136.411 84.355  1.00 53.10  ? 123 THR B CA  1 
ATOM   3748  C C   . THR B 1 177 ? 156.444 136.895 85.090  1.00 46.26  ? 123 THR B C   1 
ATOM   3749  O O   . THR B 1 177 ? 156.032 138.047 84.929  1.00 55.30  ? 123 THR B O   1 
ATOM   3750  C CB  . THR B 1 177 ? 158.941 137.046 84.949  1.00 55.94  ? 123 THR B CB  1 
ATOM   3751  O OG1 . THR B 1 177 ? 160.098 136.518 84.291  1.00 65.09  ? 123 THR B OG1 1 
ATOM   3752  C CG2 . THR B 1 177 ? 159.031 136.748 86.424  1.00 48.34  ? 123 THR B CG2 1 
ATOM   3753  N N   . VAL B 1 178 ? 155.855 136.015 85.893  1.00 39.47  ? 124 VAL B N   1 
ATOM   3754  C CA  . VAL B 1 178 ? 154.583 136.263 86.556  1.00 36.83  ? 124 VAL B CA  1 
ATOM   3755  C C   . VAL B 1 178 ? 154.817 136.389 88.054  1.00 39.15  ? 124 VAL B C   1 
ATOM   3756  O O   . VAL B 1 178 ? 155.501 135.552 88.664  1.00 49.40  ? 124 VAL B O   1 
ATOM   3757  C CB  . VAL B 1 178 ? 153.569 135.149 86.251  1.00 35.15  ? 124 VAL B CB  1 
ATOM   3758  C CG1 . VAL B 1 178 ? 152.200 135.512 86.798  1.00 35.12  ? 124 VAL B CG1 1 
ATOM   3759  C CG2 . VAL B 1 178 ? 153.503 134.893 84.760  1.00 40.23  ? 124 VAL B CG2 1 
ATOM   3760  N N   . LEU B 1 179 ? 154.256 137.446 88.636  1.00 34.69  ? 125 LEU B N   1 
ATOM   3761  C CA  . LEU B 1 179 ? 154.141 137.621 90.075  1.00 35.67  ? 125 LEU B CA  1 
ATOM   3762  C C   . LEU B 1 179 ? 152.669 137.520 90.447  1.00 36.46  ? 125 LEU B C   1 
ATOM   3763  O O   . LEU B 1 179 ? 151.828 138.220 89.870  1.00 45.23  ? 125 LEU B O   1 
ATOM   3764  C CB  . LEU B 1 179 ? 154.723 138.966 90.514  1.00 43.50  ? 125 LEU B CB  1 
ATOM   3765  C CG  . LEU B 1 179 ? 154.145 139.678 91.741  1.00 46.58  ? 125 LEU B CG  1 
ATOM   3766  C CD1 . LEU B 1 179 ? 154.303 138.858 93.012  1.00 40.90  ? 125 LEU B CD1 1 
ATOM   3767  C CD2 . LEU B 1 179 ? 154.799 141.040 91.905  1.00 48.66  ? 125 LEU B CD2 1 
ATOM   3768  N N   . TYR B 1 180 ? 152.364 136.647 91.404  1.00 31.32  ? 126 TYR B N   1 
ATOM   3769  C CA  . TYR B 1 180 ? 150.994 136.301 91.765  1.00 29.81  ? 126 TYR B CA  1 
ATOM   3770  C C   . TYR B 1 180 ? 150.861 136.408 93.276  1.00 38.51  ? 126 TYR B C   1 
ATOM   3771  O O   . TYR B 1 180 ? 151.461 135.619 94.010  1.00 51.65  ? 126 TYR B O   1 
ATOM   3772  C CB  . TYR B 1 180 ? 150.656 134.895 91.272  1.00 29.01  ? 126 TYR B CB  1 
ATOM   3773  C CG  . TYR B 1 180 ? 149.308 134.368 91.687  1.00 25.63  ? 126 TYR B CG  1 
ATOM   3774  C CD1 . TYR B 1 180 ? 148.151 135.075 91.414  1.00 26.89  ? 126 TYR B CD1 1 
ATOM   3775  C CD2 . TYR B 1 180 ? 149.191 133.141 92.321  1.00 29.76  ? 126 TYR B CD2 1 
ATOM   3776  C CE1 . TYR B 1 180 ? 146.918 134.587 91.778  1.00 28.69  ? 126 TYR B CE1 1 
ATOM   3777  C CE2 . TYR B 1 180 ? 147.961 132.645 92.689  1.00 33.12  ? 126 TYR B CE2 1 
ATOM   3778  C CZ  . TYR B 1 180 ? 146.828 133.372 92.416  1.00 31.61  ? 126 TYR B CZ  1 
ATOM   3779  O OH  . TYR B 1 180 ? 145.598 132.882 92.782  1.00 34.15  ? 126 TYR B OH  1 
ATOM   3780  N N   . GLY B 1 181 ? 150.088 137.376 93.740  1.00 36.74  ? 127 GLY B N   1 
ATOM   3781  C CA  . GLY B 1 181 ? 149.969 137.658 95.163  1.00 32.49  ? 127 GLY B CA  1 
ATOM   3782  C C   . GLY B 1 181 ? 148.554 137.452 95.663  1.00 30.71  ? 127 GLY B C   1 
ATOM   3783  O O   . GLY B 1 181 ? 147.591 137.761 94.961  1.00 39.90  ? 127 GLY B O   1 
ATOM   3784  N N   . LEU B 1 182 ? 148.440 136.934 96.885  1.00 28.21  ? 128 LEU B N   1 
ATOM   3785  C CA  . LEU B 1 182 ? 147.158 136.700 97.533  1.00 28.67  ? 128 LEU B CA  1 
ATOM   3786  C C   . LEU B 1 182 ? 147.222 137.180 98.974  1.00 34.23  ? 128 LEU B C   1 
ATOM   3787  O O   . LEU B 1 182 ? 148.299 137.269 99.563  1.00 44.27  ? 128 LEU B O   1 
ATOM   3788  C CB  . LEU B 1 182 ? 146.778 135.217 97.510  1.00 24.22  ? 128 LEU B CB  1 
ATOM   3789  C CG  . LEU B 1 182 ? 146.529 134.569 96.152  1.00 23.03  ? 128 LEU B CG  1 
ATOM   3790  C CD1 . LEU B 1 182 ? 146.608 133.064 96.282  1.00 20.81  ? 128 LEU B CD1 1 
ATOM   3791  C CD2 . LEU B 1 182 ? 145.172 134.980 95.623  1.00 32.95  ? 128 LEU B CD2 1 
ATOM   3792  N N   . ARG B 1 183 ? 146.064 137.510 99.536  1.00 27.93  ? 129 ARG B N   1 
ATOM   3793  C CA  . ARG B 1 183 ? 145.949 137.812 100.956 1.00 32.36  ? 129 ARG B CA  1 
ATOM   3794  C C   . ARG B 1 183 ? 145.155 136.693 101.612 1.00 37.66  ? 129 ARG B C   1 
ATOM   3795  O O   . ARG B 1 183 ? 143.972 136.509 101.310 1.00 43.12  ? 129 ARG B O   1 
ATOM   3796  C CB  . ARG B 1 183 ? 145.282 139.165 101.193 1.00 33.63  ? 129 ARG B CB  1 
ATOM   3797  C CG  . ARG B 1 183 ? 145.389 139.637 102.632 1.00 30.78  ? 129 ARG B CG  1 
ATOM   3798  C CD  . ARG B 1 183 ? 145.193 141.134 102.744 1.00 30.98  ? 129 ARG B CD  1 
ATOM   3799  N NE  . ARG B 1 183 ? 143.786 141.509 102.776 1.00 30.58  ? 129 ARG B NE  1 
ATOM   3800  C CZ  . ARG B 1 183 ? 143.099 141.724 103.888 1.00 32.83  ? 129 ARG B CZ  1 
ATOM   3801  N NH1 . ARG B 1 183 ? 143.661 141.605 105.080 1.00 32.41  ? 129 ARG B NH1 1 
ATOM   3802  N NH2 . ARG B 1 183 ? 141.819 142.072 103.803 1.00 29.23  ? 129 ARG B NH2 1 
ATOM   3803  N N   . ILE B 1 184 ? 145.804 135.954 102.508 1.00 35.85  ? 130 ILE B N   1 
ATOM   3804  C CA  . ILE B 1 184 ? 145.264 134.706 103.034 1.00 32.51  ? 130 ILE B CA  1 
ATOM   3805  C C   . ILE B 1 184 ? 145.261 134.765 104.553 1.00 36.91  ? 130 ILE B C   1 
ATOM   3806  O O   . ILE B 1 184 ? 146.260 135.156 105.167 1.00 44.36  ? 130 ILE B O   1 
ATOM   3807  C CB  . ILE B 1 184 ? 146.075 133.490 102.546 1.00 29.44  ? 130 ILE B CB  1 
ATOM   3808  C CG1 . ILE B 1 184 ? 146.153 133.479 101.021 1.00 26.21  ? 130 ILE B CG1 1 
ATOM   3809  C CG2 . ILE B 1 184 ? 145.458 132.201 103.056 1.00 41.72  ? 130 ILE B CG2 1 
ATOM   3810  C CD1 . ILE B 1 184 ? 147.078 132.426 100.470 1.00 27.16  ? 130 ILE B CD1 1 
ATOM   3811  N N   . THR B 1 185 ? 144.138 134.375 105.154 1.00 35.13  ? 131 THR B N   1 
ATOM   3812  C CA  . THR B 1 185 ? 144.018 134.194 106.596 1.00 43.73  ? 131 THR B CA  1 
ATOM   3813  C C   . THR B 1 185 ? 143.870 132.700 106.859 1.00 49.92  ? 131 THR B C   1 
ATOM   3814  O O   . THR B 1 185 ? 142.821 132.115 106.571 1.00 51.06  ? 131 THR B O   1 
ATOM   3815  C CB  . THR B 1 185 ? 142.831 134.976 107.157 1.00 42.76  ? 131 THR B CB  1 
ATOM   3816  O OG1 . THR B 1 185 ? 143.069 136.380 107.007 1.00 45.90  ? 131 THR B OG1 1 
ATOM   3817  C CG2 . THR B 1 185 ? 142.631 134.661 108.629 1.00 43.35  ? 131 THR B CG2 1 
ATOM   3818  N N   . THR B 1 186 ? 144.919 132.090 107.400 1.00 53.77  ? 132 THR B N   1 
ATOM   3819  C CA  . THR B 1 186 ? 144.987 130.651 107.608 1.00 53.05  ? 132 THR B CA  1 
ATOM   3820  C C   . THR B 1 186 ? 145.046 130.338 109.096 1.00 49.99  ? 132 THR B C   1 
ATOM   3821  O O   . THR B 1 186 ? 145.805 130.968 109.839 1.00 47.62  ? 132 THR B O   1 
ATOM   3822  C CB  . THR B 1 186 ? 146.204 130.052 106.896 1.00 53.18  ? 132 THR B CB  1 
ATOM   3823  O OG1 . THR B 1 186 ? 146.437 128.722 107.373 1.00 60.66  ? 132 THR B OG1 1 
ATOM   3824  C CG2 . THR B 1 186 ? 147.444 130.900 107.139 1.00 49.11  ? 132 THR B CG2 1 
ATOM   3825  N N   . THR B 1 187 ? 144.235 129.378 109.527 1.00 48.60  ? 133 THR B N   1 
ATOM   3826  C CA  . THR B 1 187 ? 144.291 128.846 110.885 1.00 43.75  ? 133 THR B CA  1 
ATOM   3827  C C   . THR B 1 187 ? 145.106 127.560 110.824 1.00 44.47  ? 133 THR B C   1 
ATOM   3828  O O   . THR B 1 187 ? 144.607 126.517 110.402 1.00 48.75  ? 133 THR B O   1 
ATOM   3829  C CB  . THR B 1 187 ? 142.891 128.603 111.438 1.00 42.68  ? 133 THR B CB  1 
ATOM   3830  O OG1 . THR B 1 187 ? 142.176 129.842 111.493 1.00 52.50  ? 133 THR B OG1 1 
ATOM   3831  C CG2 . THR B 1 187 ? 142.963 128.008 112.832 1.00 47.42  ? 133 THR B CG2 1 
ATOM   3832  N N   . ALA B 1 188 ? 146.360 127.632 111.252 1.00 45.48  ? 134 ALA B N   1 
ATOM   3833  C CA  . ALA B 1 188 ? 147.281 126.512 111.147 1.00 48.23  ? 134 ALA B CA  1 
ATOM   3834  C C   . ALA B 1 188 ? 147.422 125.818 112.493 1.00 46.32  ? 134 ALA B C   1 
ATOM   3835  O O   . ALA B 1 188 ? 147.549 126.472 113.532 1.00 56.04  ? 134 ALA B O   1 
ATOM   3836  C CB  . ALA B 1 188 ? 148.652 126.977 110.654 1.00 49.47  ? 134 ALA B CB  1 
ATOM   3837  N N   . ALA B 1 189 ? 147.401 124.489 112.465 1.00 39.52  ? 135 ALA B N   1 
ATOM   3838  C CA  . ALA B 1 189 ? 147.523 123.707 113.684 1.00 42.89  ? 135 ALA B CA  1 
ATOM   3839  C C   . ALA B 1 189 ? 148.934 123.804 114.250 1.00 54.25  ? 135 ALA B C   1 
ATOM   3840  O O   . ALA B 1 189 ? 149.915 123.957 113.519 1.00 54.42  ? 135 ALA B O   1 
ATOM   3841  C CB  . ALA B 1 189 ? 147.169 122.244 113.420 1.00 39.29  ? 135 ALA B CB  1 
ATOM   3842  N N   . CYS B 1 190 ? 149.026 123.717 115.577 1.00 58.89  ? 136 CYS B N   1 
ATOM   3843  C CA  . CYS B 1 190 ? 150.317 123.787 116.259 1.00 61.99  ? 136 CYS B CA  1 
ATOM   3844  C C   . CYS B 1 190 ? 150.194 122.992 117.555 1.00 64.94  ? 136 CYS B C   1 
ATOM   3845  O O   . CYS B 1 190 ? 149.667 123.503 118.547 1.00 66.45  ? 136 CYS B O   1 
ATOM   3846  C CB  . CYS B 1 190 ? 150.719 125.233 116.521 1.00 65.22  ? 136 CYS B CB  1 
ATOM   3847  S SG  . CYS B 1 190 ? 152.309 125.436 117.353 1.00 87.30  ? 136 CYS B SG  1 
ATOM   3848  N N   . MET B 1 191 ? 150.674 121.751 117.536 1.00 65.37  ? 137 MET B N   1 
ATOM   3849  C CA  . MET B 1 191 ? 150.700 120.946 118.748 1.00 65.65  ? 137 MET B CA  1 
ATOM   3850  C C   . MET B 1 191 ? 151.653 121.563 119.762 1.00 67.55  ? 137 MET B C   1 
ATOM   3851  O O   . MET B 1 191 ? 152.763 121.980 119.422 1.00 72.39  ? 137 MET B O   1 
ATOM   3852  C CB  . MET B 1 191 ? 151.125 119.513 118.431 1.00 67.90  ? 137 MET B CB  1 
ATOM   3853  C CG  . MET B 1 191 ? 150.072 118.681 117.712 1.00 81.18  ? 137 MET B CG  1 
ATOM   3854  S SD  . MET B 1 191 ? 148.995 117.750 118.826 1.00 123.13 ? 137 MET B SD  1 
ATOM   3855  C CE  . MET B 1 191 ? 147.762 118.976 119.259 1.00 82.37  ? 137 MET B CE  1 
ATOM   3856  N N   . MET B 1 192 ? 151.214 121.622 121.015 1.00 62.40  ? 138 MET B N   1 
ATOM   3857  C CA  . MET B 1 192 ? 151.942 122.326 122.058 1.00 59.16  ? 138 MET B CA  1 
ATOM   3858  C C   . MET B 1 192 ? 152.246 121.400 123.225 1.00 65.55  ? 138 MET B C   1 
ATOM   3859  O O   . MET B 1 192 ? 151.393 120.615 123.649 1.00 68.81  ? 138 MET B O   1 
ATOM   3860  C CB  . MET B 1 192 ? 151.154 123.539 122.545 1.00 58.04  ? 138 MET B CB  1 
ATOM   3861  C CG  . MET B 1 192 ? 150.888 124.547 121.451 1.00 68.66  ? 138 MET B CG  1 
ATOM   3862  S SD  . MET B 1 192 ? 150.025 126.018 122.015 1.00 81.57  ? 138 MET B SD  1 
ATOM   3863  C CE  . MET B 1 192 ? 149.856 126.890 120.465 1.00 66.74  ? 138 MET B CE  1 
ATOM   3864  N N   . ASP B 1 193 ? 153.468 121.506 123.738 1.00 67.20  ? 139 ASP B N   1 
ATOM   3865  C CA  . ASP B 1 193 ? 153.896 120.759 124.918 1.00 69.22  ? 139 ASP B CA  1 
ATOM   3866  C C   . ASP B 1 193 ? 153.616 121.624 126.140 1.00 66.07  ? 139 ASP B C   1 
ATOM   3867  O O   . ASP B 1 193 ? 154.394 122.520 126.474 1.00 64.30  ? 139 ASP B O   1 
ATOM   3868  C CB  . ASP B 1 193 ? 155.371 120.393 124.814 1.00 72.34  ? 139 ASP B CB  1 
ATOM   3869  C CG  . ASP B 1 193 ? 155.849 119.559 125.983 1.00 75.05  ? 139 ASP B CG  1 
ATOM   3870  O OD1 . ASP B 1 193 ? 154.997 118.997 126.704 1.00 76.02  ? 139 ASP B OD1 1 
ATOM   3871  O OD2 . ASP B 1 193 ? 157.077 119.471 126.186 1.00 76.46  ? 139 ASP B OD2 1 
ATOM   3872  N N   . LEU B 1 194 ? 152.495 121.356 126.811 1.00 63.06  ? 140 LEU B N   1 
ATOM   3873  C CA  . LEU B 1 194 ? 152.063 122.144 127.959 1.00 60.29  ? 140 LEU B CA  1 
ATOM   3874  C C   . LEU B 1 194 ? 152.634 121.634 129.276 1.00 64.15  ? 140 LEU B C   1 
ATOM   3875  O O   . LEU B 1 194 ? 152.083 121.938 130.341 1.00 64.22  ? 140 LEU B O   1 
ATOM   3876  C CB  . LEU B 1 194 ? 150.536 122.179 128.025 1.00 60.86  ? 140 LEU B CB  1 
ATOM   3877  C CG  . LEU B 1 194 ? 149.812 122.733 126.798 1.00 57.22  ? 140 LEU B CG  1 
ATOM   3878  C CD1 . LEU B 1 194 ? 148.312 122.741 127.031 1.00 55.01  ? 140 LEU B CD1 1 
ATOM   3879  C CD2 . LEU B 1 194 ? 150.311 124.127 126.467 1.00 56.34  ? 140 LEU B CD2 1 
ATOM   3880  N N   . ARG B 1 195 ? 153.728 120.869 129.236 1.00 65.55  ? 141 ARG B N   1 
ATOM   3881  C CA  . ARG B 1 195 ? 154.322 120.377 130.475 1.00 64.46  ? 141 ARG B CA  1 
ATOM   3882  C C   . ARG B 1 195 ? 154.864 121.513 131.330 1.00 62.66  ? 141 ARG B C   1 
ATOM   3883  O O   . ARG B 1 195 ? 154.980 121.370 132.551 1.00 65.29  ? 141 ARG B O   1 
ATOM   3884  C CB  . ARG B 1 195 ? 155.433 119.376 130.166 1.00 65.61  ? 141 ARG B CB  1 
ATOM   3885  C CG  . ARG B 1 195 ? 154.937 117.993 129.803 1.00 68.06  ? 141 ARG B CG  1 
ATOM   3886  C CD  . ARG B 1 195 ? 156.088 117.077 129.442 1.00 68.62  ? 141 ARG B CD  1 
ATOM   3887  N NE  . ARG B 1 195 ? 155.656 115.693 129.292 1.00 82.86  ? 141 ARG B NE  1 
ATOM   3888  C CZ  . ARG B 1 195 ? 155.120 115.189 128.189 1.00 88.68  ? 141 ARG B CZ  1 
ATOM   3889  N NH1 . ARG B 1 195 ? 154.914 115.936 127.117 1.00 83.79  ? 141 ARG B NH1 1 
ATOM   3890  N NH2 . ARG B 1 195 ? 154.780 113.904 128.162 1.00 87.61  ? 141 ARG B NH2 1 
ATOM   3891  N N   . ARG B 1 196 ? 155.201 122.644 130.712 1.00 61.02  ? 142 ARG B N   1 
ATOM   3892  C CA  . ARG B 1 196 ? 155.734 123.798 131.421 1.00 58.33  ? 142 ARG B CA  1 
ATOM   3893  C C   . ARG B 1 196 ? 154.788 124.991 131.368 1.00 60.96  ? 142 ARG B C   1 
ATOM   3894  O O   . ARG B 1 196 ? 155.203 126.123 131.631 1.00 61.89  ? 142 ARG B O   1 
ATOM   3895  C CB  . ARG B 1 196 ? 157.104 124.167 130.857 1.00 58.96  ? 142 ARG B CB  1 
ATOM   3896  C CG  . ARG B 1 196 ? 158.128 123.058 131.012 1.00 63.39  ? 142 ARG B CG  1 
ATOM   3897  C CD  . ARG B 1 196 ? 159.352 123.307 130.158 1.00 68.78  ? 142 ARG B CD  1 
ATOM   3898  N NE  . ARG B 1 196 ? 159.985 124.581 130.472 1.00 69.48  ? 142 ARG B NE  1 
ATOM   3899  C CZ  . ARG B 1 196 ? 160.868 124.755 131.444 1.00 74.20  ? 142 ARG B CZ  1 
ATOM   3900  N NH1 . ARG B 1 196 ? 161.234 123.757 132.232 1.00 72.60  ? 142 ARG B NH1 1 
ATOM   3901  N NH2 . ARG B 1 196 ? 161.399 125.960 131.630 1.00 75.06  ? 142 ARG B NH2 1 
ATOM   3902  N N   . TYR B 1 197 ? 153.528 124.754 131.030 1.00 59.54  ? 143 TYR B N   1 
ATOM   3903  C CA  . TYR B 1 197 ? 152.532 125.812 131.018 1.00 56.37  ? 143 TYR B CA  1 
ATOM   3904  C C   . TYR B 1 197 ? 152.354 126.365 132.431 1.00 64.05  ? 143 TYR B C   1 
ATOM   3905  O O   . TYR B 1 197 ? 152.338 125.596 133.399 1.00 71.20  ? 143 TYR B O   1 
ATOM   3906  C CB  . TYR B 1 197 ? 151.212 125.257 130.484 1.00 58.77  ? 143 TYR B CB  1 
ATOM   3907  C CG  . TYR B 1 197 ? 150.067 126.237 130.383 1.00 58.08  ? 143 TYR B CG  1 
ATOM   3908  C CD1 . TYR B 1 197 ? 149.229 126.469 131.463 1.00 59.74  ? 143 TYR B CD1 1 
ATOM   3909  C CD2 . TYR B 1 197 ? 149.801 126.900 129.194 1.00 58.70  ? 143 TYR B CD2 1 
ATOM   3910  C CE1 . TYR B 1 197 ? 148.176 127.350 131.371 1.00 60.99  ? 143 TYR B CE1 1 
ATOM   3911  C CE2 . TYR B 1 197 ? 148.747 127.782 129.093 1.00 60.27  ? 143 TYR B CE2 1 
ATOM   3912  C CZ  . TYR B 1 197 ? 147.938 128.002 130.185 1.00 59.75  ? 143 TYR B CZ  1 
ATOM   3913  O OH  . TYR B 1 197 ? 146.884 128.880 130.092 1.00 65.03  ? 143 TYR B OH  1 
ATOM   3914  N N   . PRO B 1 198 ? 152.212 127.688 132.593 1.00 63.00  ? 144 PRO B N   1 
ATOM   3915  C CA  . PRO B 1 198 ? 152.189 128.736 131.566 1.00 58.85  ? 144 PRO B CA  1 
ATOM   3916  C C   . PRO B 1 198 ? 153.558 129.341 131.269 1.00 61.04  ? 144 PRO B C   1 
ATOM   3917  O O   . PRO B 1 198 ? 153.644 130.351 130.582 1.00 59.59  ? 144 PRO B O   1 
ATOM   3918  C CB  . PRO B 1 198 ? 151.243 129.768 132.180 1.00 58.12  ? 144 PRO B CB  1 
ATOM   3919  C CG  . PRO B 1 198 ? 151.567 129.696 133.645 1.00 53.08  ? 144 PRO B CG  1 
ATOM   3920  C CD  . PRO B 1 198 ? 151.879 128.237 133.920 1.00 56.38  ? 144 PRO B CD  1 
ATOM   3921  N N   . LEU B 1 199 ? 154.649 128.767 131.775 1.00 58.28  ? 145 LEU B N   1 
ATOM   3922  C CA  . LEU B 1 199 ? 155.990 129.219 131.431 1.00 55.02  ? 145 LEU B CA  1 
ATOM   3923  C C   . LEU B 1 199 ? 156.552 128.484 130.223 1.00 60.45  ? 145 LEU B C   1 
ATOM   3924  O O   . LEU B 1 199 ? 157.775 128.364 130.091 1.00 59.97  ? 145 LEU B O   1 
ATOM   3925  C CB  . LEU B 1 199 ? 156.933 129.056 132.625 1.00 52.79  ? 145 LEU B CB  1 
ATOM   3926  C CG  . LEU B 1 199 ? 156.589 129.815 133.907 1.00 51.74  ? 145 LEU B CG  1 
ATOM   3927  C CD1 . LEU B 1 199 ? 155.755 128.952 134.838 1.00 55.27  ? 145 LEU B CD1 1 
ATOM   3928  C CD2 . LEU B 1 199 ? 157.853 130.294 134.600 1.00 51.08  ? 145 LEU B CD2 1 
ATOM   3929  N N   . ASP B 1 200 ? 155.685 127.990 129.345 1.00 67.68  ? 146 ASP B N   1 
ATOM   3930  C CA  . ASP B 1 200 ? 156.093 127.146 128.236 1.00 62.73  ? 146 ASP B CA  1 
ATOM   3931  C C   . ASP B 1 200 ? 156.577 127.983 127.059 1.00 58.54  ? 146 ASP B C   1 
ATOM   3932  O O   . ASP B 1 200 ? 156.258 129.167 126.923 1.00 61.83  ? 146 ASP B O   1 
ATOM   3933  C CB  . ASP B 1 200 ? 154.934 126.256 127.792 1.00 67.05  ? 146 ASP B CB  1 
ATOM   3934  C CG  . ASP B 1 200 ? 153.710 127.056 127.397 1.00 70.47  ? 146 ASP B CG  1 
ATOM   3935  O OD1 . ASP B 1 200 ? 153.565 128.197 127.880 1.00 72.07  ? 146 ASP B OD1 1 
ATOM   3936  O OD2 . ASP B 1 200 ? 152.892 126.545 126.604 1.00 71.76  ? 146 ASP B OD2 1 
ATOM   3937  N N   . GLU B 1 201 ? 157.357 127.340 126.196 1.00 64.58  ? 147 GLU B N   1 
ATOM   3938  C CA  . GLU B 1 201 ? 157.832 127.942 124.958 1.00 66.12  ? 147 GLU B CA  1 
ATOM   3939  C C   . GLU B 1 201 ? 157.415 127.033 123.814 1.00 62.23  ? 147 GLU B C   1 
ATOM   3940  O O   . GLU B 1 201 ? 157.754 125.845 123.811 1.00 65.60  ? 147 GLU B O   1 
ATOM   3941  C CB  . GLU B 1 201 ? 159.350 128.127 124.979 1.00 66.80  ? 147 GLU B CB  1 
ATOM   3942  C CG  . GLU B 1 201 ? 159.883 128.985 123.852 1.00 68.05  ? 147 GLU B CG  1 
ATOM   3943  C CD  . GLU B 1 201 ? 161.390 129.085 123.874 1.00 81.82  ? 147 GLU B CD  1 
ATOM   3944  O OE1 . GLU B 1 201 ? 162.053 128.028 123.928 1.00 80.88  ? 147 GLU B OE1 1 
ATOM   3945  O OE2 . GLU B 1 201 ? 161.912 130.219 123.852 1.00 86.45  ? 147 GLU B OE2 1 
ATOM   3946  N N   . GLN B 1 202 ? 156.685 127.584 122.854 1.00 59.58  ? 148 GLN B N   1 
ATOM   3947  C CA  . GLN B 1 202 ? 156.108 126.794 121.779 1.00 62.71  ? 148 GLN B CA  1 
ATOM   3948  C C   . GLN B 1 202 ? 156.831 127.066 120.467 1.00 61.22  ? 148 GLN B C   1 
ATOM   3949  O O   . GLN B 1 202 ? 157.568 128.040 120.321 1.00 60.33  ? 148 GLN B O   1 
ATOM   3950  C CB  . GLN B 1 202 ? 154.610 127.083 121.637 1.00 61.07  ? 148 GLN B CB  1 
ATOM   3951  C CG  . GLN B 1 202 ? 153.809 126.829 122.904 1.00 63.49  ? 148 GLN B CG  1 
ATOM   3952  C CD  . GLN B 1 202 ? 153.944 125.405 123.410 1.00 68.18  ? 148 GLN B CD  1 
ATOM   3953  O OE1 . GLN B 1 202 ? 154.223 124.483 122.644 1.00 68.92  ? 148 GLN B OE1 1 
ATOM   3954  N NE2 . GLN B 1 202 ? 153.748 125.220 124.709 1.00 65.63  ? 148 GLN B NE2 1 
ATOM   3955  N N   . ASN B 1 203 ? 156.601 126.179 119.505 1.00 64.02  ? 149 ASN B N   1 
ATOM   3956  C CA  . ASN B 1 203 ? 157.217 126.270 118.185 1.00 62.50  ? 149 ASN B CA  1 
ATOM   3957  C C   . ASN B 1 203 ? 156.144 125.939 117.159 1.00 66.32  ? 149 ASN B C   1 
ATOM   3958  O O   . ASN B 1 203 ? 155.735 124.781 117.040 1.00 67.02  ? 149 ASN B O   1 
ATOM   3959  C CB  . ASN B 1 203 ? 158.413 125.323 118.075 1.00 63.50  ? 149 ASN B CB  1 
ATOM   3960  C CG  . ASN B 1 203 ? 158.968 125.233 116.667 1.00 64.69  ? 149 ASN B CG  1 
ATOM   3961  O OD1 . ASN B 1 203 ? 158.717 126.093 115.824 1.00 63.47  ? 149 ASN B OD1 1 
ATOM   3962  N ND2 . ASN B 1 203 ? 159.740 124.185 116.410 1.00 70.55  ? 149 ASN B ND2 1 
ATOM   3963  N N   . CYS B 1 204 ? 155.691 126.949 116.421 1.00 64.97  ? 150 CYS B N   1 
ATOM   3964  C CA  . CYS B 1 204 ? 154.594 126.793 115.473 1.00 60.35  ? 150 CYS B CA  1 
ATOM   3965  C C   . CYS B 1 204 ? 155.099 127.000 114.054 1.00 61.57  ? 150 CYS B C   1 
ATOM   3966  O O   . CYS B 1 204 ? 155.845 127.948 113.785 1.00 64.99  ? 150 CYS B O   1 
ATOM   3967  C CB  . CYS B 1 204 ? 153.456 127.767 115.783 1.00 63.40  ? 150 CYS B CB  1 
ATOM   3968  S SG  . CYS B 1 204 ? 152.633 127.443 117.361 1.00 109.80 ? 150 CYS B SG  1 
ATOM   3969  N N   . THR B 1 205 ? 154.685 126.120 113.149 1.00 60.60  ? 151 THR B N   1 
ATOM   3970  C CA  . THR B 1 205 ? 155.212 126.089 111.796 1.00 48.28  ? 151 THR B CA  1 
ATOM   3971  C C   . THR B 1 205 ? 154.116 126.336 110.768 1.00 41.82  ? 151 THR B C   1 
ATOM   3972  O O   . THR B 1 205 ? 152.921 126.359 111.072 1.00 47.21  ? 151 THR B O   1 
ATOM   3973  C CB  . THR B 1 205 ? 155.900 124.749 111.505 1.00 48.59  ? 151 THR B CB  1 
ATOM   3974  O OG1 . THR B 1 205 ? 155.083 123.677 111.990 1.00 54.66  ? 151 THR B OG1 1 
ATOM   3975  C CG2 . THR B 1 205 ? 157.259 124.691 112.175 1.00 53.54  ? 151 THR B CG2 1 
ATOM   3976  N N   . LEU B 1 206 ? 154.568 126.518 109.532 1.00 38.96  ? 152 LEU B N   1 
ATOM   3977  C CA  . LEU B 1 206 ? 153.714 126.716 108.367 1.00 37.37  ? 152 LEU B CA  1 
ATOM   3978  C C   . LEU B 1 206 ? 154.385 125.981 107.218 1.00 39.06  ? 152 LEU B C   1 
ATOM   3979  O O   . LEU B 1 206 ? 155.498 126.342 106.816 1.00 45.89  ? 152 LEU B O   1 
ATOM   3980  C CB  . LEU B 1 206 ? 153.535 128.200 108.048 1.00 33.21  ? 152 LEU B CB  1 
ATOM   3981  C CG  . LEU B 1 206 ? 152.509 128.568 106.978 1.00 32.78  ? 152 LEU B CG  1 
ATOM   3982  C CD1 . LEU B 1 206 ? 151.103 128.261 107.461 1.00 33.74  ? 152 LEU B CD1 1 
ATOM   3983  C CD2 . LEU B 1 206 ? 152.638 130.033 106.598 1.00 33.26  ? 152 LEU B CD2 1 
ATOM   3984  N N   . GLU B 1 207 ? 153.726 124.939 106.717 1.00 33.55  ? 153 GLU B N   1 
ATOM   3985  C CA  . GLU B 1 207 ? 154.295 124.027 105.732 1.00 37.40  ? 153 GLU B CA  1 
ATOM   3986  C C   . GLU B 1 207 ? 153.641 124.286 104.382 1.00 37.14  ? 153 GLU B C   1 
ATOM   3987  O O   . GLU B 1 207 ? 152.454 124.004 104.195 1.00 48.51  ? 153 GLU B O   1 
ATOM   3988  C CB  . GLU B 1 207 ? 154.100 122.577 106.167 1.00 44.38  ? 153 GLU B CB  1 
ATOM   3989  C CG  . GLU B 1 207 ? 154.544 122.297 107.593 1.00 47.98  ? 153 GLU B CG  1 
ATOM   3990  C CD  . GLU B 1 207 ? 156.037 122.460 107.786 1.00 54.78  ? 153 GLU B CD  1 
ATOM   3991  O OE1 . GLU B 1 207 ? 156.788 122.313 106.800 1.00 54.89  ? 153 GLU B OE1 1 
ATOM   3992  O OE2 . GLU B 1 207 ? 156.461 122.737 108.927 1.00 63.48  ? 153 GLU B OE2 1 
ATOM   3993  N N   . ILE B 1 208 ? 154.420 124.812 103.445 1.00 30.25  ? 154 ILE B N   1 
ATOM   3994  C CA  . ILE B 1 208 ? 153.958 125.138 102.104 1.00 31.97  ? 154 ILE B CA  1 
ATOM   3995  C C   . ILE B 1 208 ? 154.443 124.050 101.160 1.00 39.90  ? 154 ILE B C   1 
ATOM   3996  O O   . ILE B 1 208 ? 155.640 123.736 101.127 1.00 48.71  ? 154 ILE B O   1 
ATOM   3997  C CB  . ILE B 1 208 ? 154.478 126.518 101.671 1.00 31.17  ? 154 ILE B CB  1 
ATOM   3998  C CG1 . ILE B 1 208 ? 154.048 127.583 102.680 1.00 31.39  ? 154 ILE B CG1 1 
ATOM   3999  C CG2 . ILE B 1 208 ? 153.991 126.855 100.285 1.00 32.22  ? 154 ILE B CG2 1 
ATOM   4000  C CD1 . ILE B 1 208 ? 154.845 128.858 102.592 1.00 28.29  ? 154 ILE B CD1 1 
ATOM   4001  N N   . GLU B 1 209 ? 153.521 123.471 100.393 1.00 39.62  ? 155 GLU B N   1 
ATOM   4002  C CA  . GLU B 1 209 ? 153.868 122.346 99.540  1.00 37.27  ? 155 GLU B CA  1 
ATOM   4003  C C   . GLU B 1 209 ? 153.059 122.401 98.253  1.00 38.17  ? 155 GLU B C   1 
ATOM   4004  O O   . GLU B 1 209 ? 151.949 122.938 98.219  1.00 41.66  ? 155 GLU B O   1 
ATOM   4005  C CB  . GLU B 1 209 ? 153.634 121.018 100.271 1.00 41.14  ? 155 GLU B CB  1 
ATOM   4006  C CG  . GLU B 1 209 ? 154.037 119.778 99.495  1.00 48.61  ? 155 GLU B CG  1 
ATOM   4007  C CD  . GLU B 1 209 ? 154.095 118.540 100.363 1.00 59.22  ? 155 GLU B CD  1 
ATOM   4008  O OE1 . GLU B 1 209 ? 154.646 118.623 101.481 1.00 65.11  ? 155 GLU B OE1 1 
ATOM   4009  O OE2 . GLU B 1 209 ? 153.586 117.486 99.930  1.00 64.64  ? 155 GLU B OE2 1 
ATOM   4010  N N   . SER B 1 210 ? 153.634 121.845 97.189  1.00 37.94  ? 156 SER B N   1 
ATOM   4011  C CA  . SER B 1 210 ? 152.898 121.620 95.955  1.00 36.35  ? 156 SER B CA  1 
ATOM   4012  C C   . SER B 1 210 ? 152.014 120.392 96.114  1.00 44.05  ? 156 SER B C   1 
ATOM   4013  O O   . SER B 1 210 ? 152.468 119.350 96.594  1.00 52.33  ? 156 SER B O   1 
ATOM   4014  C CB  . SER B 1 210 ? 153.856 121.435 94.781  1.00 39.36  ? 156 SER B CB  1 
ATOM   4015  O OG  . SER B 1 210 ? 153.155 121.037 93.616  1.00 47.13  ? 156 SER B OG  1 
ATOM   4016  N N   . TYR B 1 211 ? 150.750 120.514 95.711  1.00 42.16  ? 157 TYR B N   1 
ATOM   4017  C CA  . TYR B 1 211 ? 149.795 119.442 95.963  1.00 39.00  ? 157 TYR B CA  1 
ATOM   4018  C C   . TYR B 1 211 ? 149.936 118.313 94.948  1.00 45.99  ? 157 TYR B C   1 
ATOM   4019  O O   . TYR B 1 211 ? 150.155 117.155 95.317  1.00 50.75  ? 157 TYR B O   1 
ATOM   4020  C CB  . TYR B 1 211 ? 148.369 119.993 95.959  1.00 33.09  ? 157 TYR B CB  1 
ATOM   4021  C CG  . TYR B 1 211 ? 147.353 118.976 96.406  1.00 39.78  ? 157 TYR B CG  1 
ATOM   4022  C CD1 . TYR B 1 211 ? 147.181 118.688 97.752  1.00 43.19  ? 157 TYR B CD1 1 
ATOM   4023  C CD2 . TYR B 1 211 ? 146.578 118.289 95.485  1.00 40.49  ? 157 TYR B CD2 1 
ATOM   4024  C CE1 . TYR B 1 211 ? 146.261 117.753 98.167  1.00 37.90  ? 157 TYR B CE1 1 
ATOM   4025  C CE2 . TYR B 1 211 ? 145.655 117.352 95.892  1.00 38.64  ? 157 TYR B CE2 1 
ATOM   4026  C CZ  . TYR B 1 211 ? 145.502 117.088 97.232  1.00 36.94  ? 157 TYR B CZ  1 
ATOM   4027  O OH  . TYR B 1 211 ? 144.583 116.154 97.641  1.00 43.30  ? 157 TYR B OH  1 
ATOM   4028  N N   . GLY B 1 212 ? 149.812 118.633 93.664  1.00 44.17  ? 158 GLY B N   1 
ATOM   4029  C CA  . GLY B 1 212 ? 149.837 117.611 92.638  1.00 43.02  ? 158 GLY B CA  1 
ATOM   4030  C C   . GLY B 1 212 ? 151.199 117.388 92.016  1.00 46.09  ? 158 GLY B C   1 
ATOM   4031  O O   . GLY B 1 212 ? 151.637 116.245 91.860  1.00 48.38  ? 158 GLY B O   1 
ATOM   4032  N N   . TYR B 1 213 ? 151.876 118.472 91.652  1.00 45.47  ? 159 TYR B N   1 
ATOM   4033  C CA  . TYR B 1 213 ? 153.153 118.361 90.965  1.00 48.26  ? 159 TYR B CA  1 
ATOM   4034  C C   . TYR B 1 213 ? 154.250 117.905 91.919  1.00 49.04  ? 159 TYR B C   1 
ATOM   4035  O O   . TYR B 1 213 ? 154.207 118.160 93.124  1.00 52.34  ? 159 TYR B O   1 
ATOM   4036  C CB  . TYR B 1 213 ? 153.532 119.697 90.331  1.00 45.55  ? 159 TYR B CB  1 
ATOM   4037  C CG  . TYR B 1 213 ? 152.496 120.218 89.367  1.00 49.02  ? 159 TYR B CG  1 
ATOM   4038  C CD1 . TYR B 1 213 ? 152.493 119.818 88.040  1.00 52.36  ? 159 TYR B CD1 1 
ATOM   4039  C CD2 . TYR B 1 213 ? 151.515 121.105 89.785  1.00 47.94  ? 159 TYR B CD2 1 
ATOM   4040  C CE1 . TYR B 1 213 ? 151.546 120.289 87.156  1.00 56.84  ? 159 TYR B CE1 1 
ATOM   4041  C CE2 . TYR B 1 213 ? 150.564 121.581 88.909  1.00 46.98  ? 159 TYR B CE2 1 
ATOM   4042  C CZ  . TYR B 1 213 ? 150.584 121.171 87.595  1.00 55.42  ? 159 TYR B CZ  1 
ATOM   4043  O OH  . TYR B 1 213 ? 149.638 121.642 86.716  1.00 62.90  ? 159 TYR B OH  1 
ATOM   4044  N N   . THR B 1 214 ? 155.245 117.224 91.359  1.00 51.54  ? 160 THR B N   1 
ATOM   4045  C CA  . THR B 1 214 ? 156.367 116.697 92.114  1.00 50.88  ? 160 THR B CA  1 
ATOM   4046  C C   . THR B 1 214 ? 157.607 117.551 91.867  1.00 55.87  ? 160 THR B C   1 
ATOM   4047  O O   . THR B 1 214 ? 157.570 118.558 91.156  1.00 62.03  ? 160 THR B O   1 
ATOM   4048  C CB  . THR B 1 214 ? 156.625 115.239 91.738  1.00 57.81  ? 160 THR B CB  1 
ATOM   4049  O OG1 . THR B 1 214 ? 157.120 115.172 90.395  1.00 62.25  ? 160 THR B OG1 1 
ATOM   4050  C CG2 . THR B 1 214 ? 155.342 114.433 91.834  1.00 62.48  ? 160 THR B CG2 1 
ATOM   4051  N N   . THR B 1 215 ? 158.726 117.139 92.465  1.00 55.23  ? 161 THR B N   1 
ATOM   4052  C CA  . THR B 1 215 ? 159.982 117.852 92.268  1.00 56.28  ? 161 THR B CA  1 
ATOM   4053  C C   . THR B 1 215 ? 160.503 117.745 90.844  1.00 57.72  ? 161 THR B C   1 
ATOM   4054  O O   . THR B 1 215 ? 161.392 118.517 90.469  1.00 61.74  ? 161 THR B O   1 
ATOM   4055  C CB  . THR B 1 215 ? 161.048 117.337 93.235  1.00 64.85  ? 161 THR B CB  1 
ATOM   4056  O OG1 . THR B 1 215 ? 161.189 115.920 93.082  1.00 76.10  ? 161 THR B OG1 1 
ATOM   4057  C CG2 . THR B 1 215 ? 160.663 117.656 94.669  1.00 62.52  ? 161 THR B CG2 1 
ATOM   4058  N N   . ASP B 1 216 ? 159.984 116.812 90.048  1.00 60.79  ? 162 ASP B N   1 
ATOM   4059  C CA  . ASP B 1 216 ? 160.351 116.737 88.642  1.00 68.88  ? 162 ASP B CA  1 
ATOM   4060  C C   . ASP B 1 216 ? 159.596 117.745 87.789  1.00 67.14  ? 162 ASP B C   1 
ATOM   4061  O O   . ASP B 1 216 ? 159.963 117.947 86.628  1.00 69.01  ? 162 ASP B O   1 
ATOM   4062  C CB  . ASP B 1 216 ? 160.107 115.324 88.110  1.00 71.23  ? 162 ASP B CB  1 
ATOM   4063  C CG  . ASP B 1 216 ? 160.896 114.274 88.867  1.00 80.81  ? 162 ASP B CG  1 
ATOM   4064  O OD1 . ASP B 1 216 ? 162.015 114.585 89.325  1.00 75.99  ? 162 ASP B OD1 1 
ATOM   4065  O OD2 . ASP B 1 216 ? 160.395 113.138 89.007  1.00 88.67  ? 162 ASP B OD2 1 
ATOM   4066  N N   . ASP B 1 217 ? 158.559 118.379 88.337  1.00 62.59  ? 163 ASP B N   1 
ATOM   4067  C CA  . ASP B 1 217 ? 157.778 119.367 87.613  1.00 57.51  ? 163 ASP B CA  1 
ATOM   4068  C C   . ASP B 1 217 ? 157.778 120.745 88.252  1.00 58.62  ? 163 ASP B C   1 
ATOM   4069  O O   . ASP B 1 217 ? 157.444 121.718 87.569  1.00 65.90  ? 163 ASP B O   1 
ATOM   4070  C CB  . ASP B 1 217 ? 156.321 118.899 87.467  1.00 59.62  ? 163 ASP B CB  1 
ATOM   4071  C CG  . ASP B 1 217 ? 156.211 117.549 86.793  1.00 68.43  ? 163 ASP B CG  1 
ATOM   4072  O OD1 . ASP B 1 217 ? 157.117 117.203 86.007  1.00 74.16  ? 163 ASP B OD1 1 
ATOM   4073  O OD2 . ASP B 1 217 ? 155.220 116.833 87.047  1.00 68.72  ? 163 ASP B OD2 1 
ATOM   4074  N N   . ILE B 1 218 ? 158.146 120.864 89.525  1.00 56.93  ? 164 ILE B N   1 
ATOM   4075  C CA  . ILE B 1 218 ? 158.079 122.143 90.220  1.00 51.22  ? 164 ILE B CA  1 
ATOM   4076  C C   . ILE B 1 218 ? 159.100 122.130 91.348  1.00 47.97  ? 164 ILE B C   1 
ATOM   4077  O O   . ILE B 1 218 ? 159.372 121.087 91.947  1.00 54.84  ? 164 ILE B O   1 
ATOM   4078  C CB  . ILE B 1 218 ? 156.645 122.420 90.734  1.00 44.34  ? 164 ILE B CB  1 
ATOM   4079  C CG1 . ILE B 1 218 ? 156.482 123.888 91.125  1.00 43.32  ? 164 ILE B CG1 1 
ATOM   4080  C CG2 . ILE B 1 218 ? 156.303 121.512 91.905  1.00 49.48  ? 164 ILE B CG2 1 
ATOM   4081  C CD1 . ILE B 1 218 ? 155.053 124.271 91.430  1.00 45.09  ? 164 ILE B CD1 1 
ATOM   4082  N N   . GLU B 1 219 ? 159.686 123.294 91.612  1.00 40.10  ? 165 GLU B N   1 
ATOM   4083  C CA  . GLU B 1 219 ? 160.617 123.470 92.715  1.00 44.04  ? 165 GLU B CA  1 
ATOM   4084  C C   . GLU B 1 219 ? 160.256 124.732 93.482  1.00 46.77  ? 165 GLU B C   1 
ATOM   4085  O O   . GLU B 1 219 ? 159.792 125.717 92.904  1.00 54.15  ? 165 GLU B O   1 
ATOM   4086  C CB  . GLU B 1 219 ? 162.067 123.554 92.226  1.00 46.24  ? 165 GLU B CB  1 
ATOM   4087  C CG  . GLU B 1 219 ? 162.570 122.290 91.555  1.00 57.88  ? 165 GLU B CG  1 
ATOM   4088  C CD  . GLU B 1 219 ? 164.039 122.372 91.189  1.00 73.63  ? 165 GLU B CD  1 
ATOM   4089  O OE1 . GLU B 1 219 ? 164.705 123.338 91.618  1.00 80.59  ? 165 GLU B OE1 1 
ATOM   4090  O OE2 . GLU B 1 219 ? 164.529 121.474 90.473  1.00 71.93  ? 165 GLU B OE2 1 
ATOM   4091  N N   . PHE B 1 220 ? 160.479 124.695 94.792  1.00 37.70  ? 166 PHE B N   1 
ATOM   4092  C CA  . PHE B 1 220 ? 160.165 125.807 95.675  1.00 31.75  ? 166 PHE B CA  1 
ATOM   4093  C C   . PHE B 1 220 ? 161.440 126.349 96.300  1.00 38.67  ? 166 PHE B C   1 
ATOM   4094  O O   . PHE B 1 220 ? 162.324 125.584 96.695  1.00 50.46  ? 166 PHE B O   1 
ATOM   4095  C CB  . PHE B 1 220 ? 159.200 125.389 96.787  1.00 34.91  ? 166 PHE B CB  1 
ATOM   4096  C CG  . PHE B 1 220 ? 157.791 125.172 96.325  1.00 35.52  ? 166 PHE B CG  1 
ATOM   4097  C CD1 . PHE B 1 220 ? 157.404 125.510 95.044  1.00 35.13  ? 166 PHE B CD1 1 
ATOM   4098  C CD2 . PHE B 1 220 ? 156.850 124.636 97.184  1.00 37.47  ? 166 PHE B CD2 1 
ATOM   4099  C CE1 . PHE B 1 220 ? 156.109 125.310 94.626  1.00 36.57  ? 166 PHE B CE1 1 
ATOM   4100  C CE2 . PHE B 1 220 ? 155.554 124.435 96.773  1.00 35.50  ? 166 PHE B CE2 1 
ATOM   4101  C CZ  . PHE B 1 220 ? 155.182 124.771 95.492  1.00 35.08  ? 166 PHE B CZ  1 
ATOM   4102  N N   . TYR B 1 221 ? 161.525 127.673 96.396  1.00 36.19  ? 167 TYR B N   1 
ATOM   4103  C CA  . TYR B 1 221 ? 162.622 128.315 97.101  1.00 39.28  ? 167 TYR B CA  1 
ATOM   4104  C C   . TYR B 1 221 ? 162.129 129.638 97.665  1.00 43.62  ? 167 TYR B C   1 
ATOM   4105  O O   . TYR B 1 221 ? 161.131 130.199 97.206  1.00 48.07  ? 167 TYR B O   1 
ATOM   4106  C CB  . TYR B 1 221 ? 163.838 128.529 96.190  1.00 38.72  ? 167 TYR B CB  1 
ATOM   4107  C CG  . TYR B 1 221 ? 163.624 129.535 95.081  1.00 39.69  ? 167 TYR B CG  1 
ATOM   4108  C CD1 . TYR B 1 221 ? 163.133 129.142 93.845  1.00 39.44  ? 167 TYR B CD1 1 
ATOM   4109  C CD2 . TYR B 1 221 ? 163.925 130.876 95.267  1.00 37.37  ? 167 TYR B CD2 1 
ATOM   4110  C CE1 . TYR B 1 221 ? 162.941 130.059 92.830  1.00 37.58  ? 167 TYR B CE1 1 
ATOM   4111  C CE2 . TYR B 1 221 ? 163.734 131.797 94.261  1.00 33.57  ? 167 TYR B CE2 1 
ATOM   4112  C CZ  . TYR B 1 221 ? 163.244 131.385 93.045  1.00 36.05  ? 167 TYR B CZ  1 
ATOM   4113  O OH  . TYR B 1 221 ? 163.056 132.306 92.043  1.00 49.40  ? 167 TYR B OH  1 
ATOM   4114  N N   . TRP B 1 222 ? 162.837 130.128 98.678  1.00 43.01  ? 168 TRP B N   1 
ATOM   4115  C CA  . TRP B 1 222 ? 162.532 131.428 99.261  1.00 42.13  ? 168 TRP B CA  1 
ATOM   4116  C C   . TRP B 1 222 ? 163.204 132.517 98.435  1.00 44.85  ? 168 TRP B C   1 
ATOM   4117  O O   . TRP B 1 222 ? 164.428 132.513 98.271  1.00 49.08  ? 168 TRP B O   1 
ATOM   4118  C CB  . TRP B 1 222 ? 162.999 131.489 100.712 1.00 40.98  ? 168 TRP B CB  1 
ATOM   4119  C CG  . TRP B 1 222 ? 162.242 130.594 101.633 1.00 35.75  ? 168 TRP B CG  1 
ATOM   4120  C CD1 . TRP B 1 222 ? 162.707 129.471 102.248 1.00 38.61  ? 168 TRP B CD1 1 
ATOM   4121  C CD2 . TRP B 1 222 ? 160.880 130.744 102.048 1.00 36.80  ? 168 TRP B CD2 1 
ATOM   4122  N NE1 . TRP B 1 222 ? 161.721 128.912 103.022 1.00 41.37  ? 168 TRP B NE1 1 
ATOM   4123  C CE2 . TRP B 1 222 ? 160.588 129.674 102.915 1.00 39.97  ? 168 TRP B CE2 1 
ATOM   4124  C CE3 . TRP B 1 222 ? 159.879 131.678 101.769 1.00 40.10  ? 168 TRP B CE3 1 
ATOM   4125  C CZ2 . TRP B 1 222 ? 159.339 129.514 103.507 1.00 37.59  ? 168 TRP B CZ2 1 
ATOM   4126  C CZ3 . TRP B 1 222 ? 158.641 131.517 102.357 1.00 36.51  ? 168 TRP B CZ3 1 
ATOM   4127  C CH2 . TRP B 1 222 ? 158.381 130.443 103.216 1.00 30.13  ? 168 TRP B CH2 1 
ATOM   4128  N N   . ARG B 1 223 ? 162.411 133.455 97.928  1.00 41.68  ? 169 ARG B N   1 
ATOM   4129  C CA  . ARG B 1 223 ? 162.935 134.520 97.081  1.00 47.97  ? 169 ARG B CA  1 
ATOM   4130  C C   . ARG B 1 223 ? 163.540 135.596 97.970  1.00 55.47  ? 169 ARG B C   1 
ATOM   4131  O O   . ARG B 1 223 ? 162.826 136.268 98.720  1.00 57.07  ? 169 ARG B O   1 
ATOM   4132  C CB  . ARG B 1 223 ? 161.832 135.088 96.195  1.00 47.83  ? 169 ARG B CB  1 
ATOM   4133  C CG  . ARG B 1 223 ? 162.327 136.045 95.135  1.00 51.56  ? 169 ARG B CG  1 
ATOM   4134  C CD  . ARG B 1 223 ? 161.191 136.473 94.233  1.00 54.33  ? 169 ARG B CD  1 
ATOM   4135  N NE  . ARG B 1 223 ? 161.646 137.327 93.144  1.00 64.20  ? 169 ARG B NE  1 
ATOM   4136  C CZ  . ARG B 1 223 ? 161.636 138.652 93.178  1.00 69.56  ? 169 ARG B CZ  1 
ATOM   4137  N NH1 . ARG B 1 223 ? 161.198 139.313 94.237  1.00 70.93  ? 169 ARG B NH1 1 
ATOM   4138  N NH2 . ARG B 1 223 ? 162.075 139.331 92.123  1.00 69.97  ? 169 ARG B NH2 1 
ATOM   4139  N N   . GLY B 1 224 ? 164.854 135.764 97.884  1.00 55.94  ? 170 GLY B N   1 
ATOM   4140  C CA  . GLY B 1 224 ? 165.572 136.679 98.744  1.00 52.90  ? 170 GLY B CA  1 
ATOM   4141  C C   . GLY B 1 224 ? 166.185 136.059 99.979  1.00 58.22  ? 170 GLY B C   1 
ATOM   4142  O O   . GLY B 1 224 ? 166.622 136.800 100.866 1.00 65.70  ? 170 GLY B O   1 
ATOM   4143  N N   . GLY B 1 225 ? 166.238 134.731 100.063 1.00 57.00  ? 171 GLY B N   1 
ATOM   4144  C CA  . GLY B 1 225 ? 166.865 134.090 101.207 1.00 60.75  ? 171 GLY B CA  1 
ATOM   4145  C C   . GLY B 1 225 ? 166.065 134.291 102.479 1.00 66.28  ? 171 GLY B C   1 
ATOM   4146  O O   . GLY B 1 225 ? 164.828 134.296 102.475 1.00 69.59  ? 171 GLY B O   1 
ATOM   4147  N N   . ASP B 1 226 ? 166.784 134.460 103.592 1.00 66.65  ? 172 ASP B N   1 
ATOM   4148  C CA  . ASP B 1 226 ? 166.137 134.634 104.887 1.00 67.30  ? 172 ASP B CA  1 
ATOM   4149  C C   . ASP B 1 226 ? 165.290 135.897 104.948 1.00 69.76  ? 172 ASP B C   1 
ATOM   4150  O O   . ASP B 1 226 ? 164.418 136.004 105.816 1.00 69.80  ? 172 ASP B O   1 
ATOM   4151  C CB  . ASP B 1 226 ? 167.187 134.653 106.000 1.00 69.46  ? 172 ASP B CB  1 
ATOM   4152  C CG  . ASP B 1 226 ? 167.793 133.286 106.253 1.00 80.91  ? 172 ASP B CG  1 
ATOM   4153  O OD1 . ASP B 1 226 ? 167.328 132.305 105.636 1.00 76.64  ? 172 ASP B OD1 1 
ATOM   4154  O OD2 . ASP B 1 226 ? 168.734 133.192 107.068 1.00 89.63  ? 172 ASP B OD2 1 
ATOM   4155  N N   . LYS B 1 227 ? 165.520 136.850 104.049 1.00 64.90  ? 173 LYS B N   1 
ATOM   4156  C CA  . LYS B 1 227 ? 164.699 138.049 103.966 1.00 62.11  ? 173 LYS B CA  1 
ATOM   4157  C C   . LYS B 1 227 ? 163.396 137.818 103.214 1.00 60.30  ? 173 LYS B C   1 
ATOM   4158  O O   . LYS B 1 227 ? 162.695 138.786 102.905 1.00 63.44  ? 173 LYS B O   1 
ATOM   4159  C CB  . LYS B 1 227 ? 165.487 139.179 103.301 1.00 70.73  ? 173 LYS B CB  1 
ATOM   4160  C CG  . LYS B 1 227 ? 166.753 139.568 104.041 1.00 74.53  ? 173 LYS B CG  1 
ATOM   4161  C CD  . LYS B 1 227 ? 167.471 140.702 103.331 1.00 82.90  ? 173 LYS B CD  1 
ATOM   4162  C CE  . LYS B 1 227 ? 168.743 141.094 104.059 1.00 89.03  ? 173 LYS B CE  1 
ATOM   4163  N NZ  . LYS B 1 227 ? 169.450 142.204 103.366 1.00 95.32  ? 173 LYS B NZ  1 
ATOM   4164  N N   . ALA B 1 228 ? 163.057 136.563 102.915 1.00 59.98  ? 174 ALA B N   1 
ATOM   4165  C CA  . ALA B 1 228 ? 161.855 136.266 102.150 1.00 56.48  ? 174 ALA B CA  1 
ATOM   4166  C C   . ALA B 1 228 ? 160.580 136.403 102.970 1.00 54.53  ? 174 ALA B C   1 
ATOM   4167  O O   . ALA B 1 228 ? 159.494 136.482 102.388 1.00 55.08  ? 174 ALA B O   1 
ATOM   4168  C CB  . ALA B 1 228 ? 161.939 134.856 101.569 1.00 54.05  ? 174 ALA B CB  1 
ATOM   4169  N N   . VAL B 1 229 ? 160.682 136.434 104.295 1.00 53.45  ? 175 VAL B N   1 
ATOM   4170  C CA  . VAL B 1 229 ? 159.531 136.610 105.172 1.00 53.78  ? 175 VAL B CA  1 
ATOM   4171  C C   . VAL B 1 229 ? 159.721 137.910 105.938 1.00 59.60  ? 175 VAL B C   1 
ATOM   4172  O O   . VAL B 1 229 ? 160.739 138.093 106.616 1.00 59.40  ? 175 VAL B O   1 
ATOM   4173  C CB  . VAL B 1 229 ? 159.350 135.421 106.127 1.00 53.72  ? 175 VAL B CB  1 
ATOM   4174  C CG1 . VAL B 1 229 ? 158.269 135.722 107.146 1.00 57.57  ? 175 VAL B CG1 1 
ATOM   4175  C CG2 . VAL B 1 229 ? 158.996 134.173 105.340 1.00 44.37  ? 175 VAL B CG2 1 
ATOM   4176  N N   . THR B 1 230 ? 158.746 138.809 105.828 1.00 59.44  ? 176 THR B N   1 
ATOM   4177  C CA  . THR B 1 230 ? 158.826 140.142 106.401 1.00 62.31  ? 176 THR B CA  1 
ATOM   4178  C C   . THR B 1 230 ? 157.671 140.377 107.365 1.00 63.21  ? 176 THR B C   1 
ATOM   4179  O O   . THR B 1 230 ? 156.663 139.666 107.349 1.00 61.11  ? 176 THR B O   1 
ATOM   4180  C CB  . THR B 1 230 ? 158.807 141.220 105.308 1.00 63.76  ? 176 THR B CB  1 
ATOM   4181  O OG1 . THR B 1 230 ? 157.585 141.128 104.566 1.00 61.09  ? 176 THR B OG1 1 
ATOM   4182  C CG2 . THR B 1 230 ? 159.982 141.044 104.361 1.00 62.66  ? 176 THR B CG2 1 
ATOM   4183  N N   . GLY B 1 231 ? 157.831 141.395 108.208 1.00 68.16  ? 177 GLY B N   1 
ATOM   4184  C CA  . GLY B 1 231 ? 156.801 141.759 109.157 1.00 67.90  ? 177 GLY B CA  1 
ATOM   4185  C C   . GLY B 1 231 ? 156.777 140.944 110.427 1.00 73.67  ? 177 GLY B C   1 
ATOM   4186  O O   . GLY B 1 231 ? 155.841 141.093 111.220 1.00 78.24  ? 177 GLY B O   1 
ATOM   4187  N N   . VAL B 1 232 ? 157.772 140.084 110.648 1.00 72.85  ? 178 VAL B N   1 
ATOM   4188  C CA  . VAL B 1 232 ? 157.766 139.229 111.831 1.00 72.28  ? 178 VAL B CA  1 
ATOM   4189  C C   . VAL B 1 232 ? 157.962 140.054 113.097 1.00 76.50  ? 178 VAL B C   1 
ATOM   4190  O O   . VAL B 1 232 ? 157.300 139.820 114.114 1.00 70.40  ? 178 VAL B O   1 
ATOM   4191  C CB  . VAL B 1 232 ? 158.838 138.133 111.703 1.00 69.45  ? 178 VAL B CB  1 
ATOM   4192  C CG1 . VAL B 1 232 ? 158.735 137.158 112.862 1.00 68.70  ? 178 VAL B CG1 1 
ATOM   4193  C CG2 . VAL B 1 232 ? 158.701 137.411 110.377 1.00 64.73  ? 178 VAL B CG2 1 
ATOM   4194  N N   . GLU B 1 233 ? 158.873 141.030 113.060 1.00 85.09  ? 179 GLU B N   1 
ATOM   4195  C CA  . GLU B 1 233 ? 159.192 141.794 114.260 1.00 85.25  ? 179 GLU B CA  1 
ATOM   4196  C C   . GLU B 1 233 ? 158.088 142.768 114.650 1.00 82.46  ? 179 GLU B C   1 
ATOM   4197  O O   . GLU B 1 233 ? 158.105 143.280 115.773 1.00 83.86  ? 179 GLU B O   1 
ATOM   4198  C CB  . GLU B 1 233 ? 160.502 142.562 114.073 1.00 82.74  ? 179 GLU B CB  1 
ATOM   4199  C CG  . GLU B 1 233 ? 160.405 143.746 113.124 1.00 86.36  ? 179 GLU B CG  1 
ATOM   4200  C CD  . GLU B 1 233 ? 160.361 143.327 111.670 1.00 95.07  ? 179 GLU B CD  1 
ATOM   4201  O OE1 . GLU B 1 233 ? 160.858 142.225 111.356 1.00 92.82  ? 179 GLU B OE1 1 
ATOM   4202  O OE2 . GLU B 1 233 ? 159.827 144.095 110.843 1.00 98.63  ? 179 GLU B OE2 1 
ATOM   4203  N N   . ARG B 1 234 ? 157.138 143.037 113.759 1.00 81.94  ? 180 ARG B N   1 
ATOM   4204  C CA  . ARG B 1 234 ? 156.078 144.010 114.000 1.00 84.50  ? 180 ARG B CA  1 
ATOM   4205  C C   . ARG B 1 234 ? 154.743 143.331 114.284 1.00 83.78  ? 180 ARG B C   1 
ATOM   4206  O O   . ARG B 1 234 ? 153.683 143.828 113.901 1.00 86.97  ? 180 ARG B O   1 
ATOM   4207  C CB  . ARG B 1 234 ? 155.940 144.960 112.815 1.00 88.44  ? 180 ARG B CB  1 
ATOM   4208  C CG  . ARG B 1 234 ? 157.241 145.599 112.367 1.00 93.85  ? 180 ARG B CG  1 
ATOM   4209  C CD  . ARG B 1 234 ? 157.052 146.398 111.085 1.00 103.11 ? 180 ARG B CD  1 
ATOM   4210  N NE  . ARG B 1 234 ? 156.585 145.571 109.978 1.00 109.02 ? 180 ARG B NE  1 
ATOM   4211  C CZ  . ARG B 1 234 ? 155.324 145.501 109.573 1.00 107.04 ? 180 ARG B CZ  1 
ATOM   4212  N NH1 . ARG B 1 234 ? 154.368 146.199 110.163 1.00 105.64 ? 180 ARG B NH1 1 
ATOM   4213  N NH2 . ARG B 1 234 ? 155.015 144.710 108.549 1.00 96.07  ? 180 ARG B NH2 1 
ATOM   4214  N N   . ILE B 1 235 ? 154.777 142.189 114.962 1.00 82.88  ? 181 ILE B N   1 
ATOM   4215  C CA  . ILE B 1 235 ? 153.575 141.432 115.287 1.00 80.89  ? 181 ILE B CA  1 
ATOM   4216  C C   . ILE B 1 235 ? 153.176 141.744 116.721 1.00 81.50  ? 181 ILE B C   1 
ATOM   4217  O O   . ILE B 1 235 ? 153.987 141.611 117.646 1.00 79.05  ? 181 ILE B O   1 
ATOM   4218  C CB  . ILE B 1 235 ? 153.793 139.924 115.085 1.00 75.23  ? 181 ILE B CB  1 
ATOM   4219  C CG1 . ILE B 1 235 ? 153.971 139.620 113.597 1.00 67.66  ? 181 ILE B CG1 1 
ATOM   4220  C CG2 . ILE B 1 235 ? 152.633 139.135 115.663 1.00 69.93  ? 181 ILE B CG2 1 
ATOM   4221  C CD1 . ILE B 1 235 ? 154.136 138.156 113.284 1.00 62.45  ? 181 ILE B CD1 1 
ATOM   4222  N N   . GLU B 1 236 ? 151.926 142.165 116.904 1.00 82.02  ? 182 GLU B N   1 
ATOM   4223  C CA  . GLU B 1 236 ? 151.409 142.560 118.212 1.00 81.76  ? 182 GLU B CA  1 
ATOM   4224  C C   . GLU B 1 236 ? 150.701 141.364 118.832 1.00 79.91  ? 182 GLU B C   1 
ATOM   4225  O O   . GLU B 1 236 ? 149.516 141.124 118.599 1.00 82.01  ? 182 GLU B O   1 
ATOM   4226  C CB  . GLU B 1 236 ? 150.480 143.759 118.076 1.00 88.97  ? 182 GLU B CB  1 
ATOM   4227  C CG  . GLU B 1 236 ? 151.156 145.000 117.520 1.00 94.84  ? 182 GLU B CG  1 
ATOM   4228  C CD  . GLU B 1 236 ? 150.223 145.840 116.669 1.00 100.32 ? 182 GLU B CD  1 
ATOM   4229  O OE1 . GLU B 1 236 ? 149.267 145.273 116.101 1.00 99.44  ? 182 GLU B OE1 1 
ATOM   4230  O OE2 . GLU B 1 236 ? 150.446 147.064 116.569 1.00 107.24 ? 182 GLU B OE2 1 
ATOM   4231  N N   . LEU B 1 237 ? 151.438 140.602 119.634 1.00 73.15  ? 183 LEU B N   1 
ATOM   4232  C CA  . LEU B 1 237 ? 150.870 139.479 120.369 1.00 68.64  ? 183 LEU B CA  1 
ATOM   4233  C C   . LEU B 1 237 ? 150.772 139.844 121.841 1.00 75.76  ? 183 LEU B C   1 
ATOM   4234  O O   . LEU B 1 237 ? 151.807 139.936 122.519 1.00 78.58  ? 183 LEU B O   1 
ATOM   4235  C CB  . LEU B 1 237 ? 151.722 138.223 120.187 1.00 64.36  ? 183 LEU B CB  1 
ATOM   4236  C CG  . LEU B 1 237 ? 151.415 137.366 118.961 1.00 63.70  ? 183 LEU B CG  1 
ATOM   4237  C CD1 . LEU B 1 237 ? 152.390 136.207 118.868 1.00 60.87  ? 183 LEU B CD1 1 
ATOM   4238  C CD2 . LEU B 1 237 ? 149.985 136.860 119.025 1.00 60.66  ? 183 LEU B CD2 1 
ATOM   4239  N N   . PRO B 1 238 ? 149.570 140.078 122.373 1.00 77.45  ? 184 PRO B N   1 
ATOM   4240  C CA  . PRO B 1 238 ? 149.465 140.440 123.796 1.00 75.94  ? 184 PRO B CA  1 
ATOM   4241  C C   . PRO B 1 238 ? 150.030 139.389 124.734 1.00 74.71  ? 184 PRO B C   1 
ATOM   4242  O O   . PRO B 1 238 ? 150.671 139.737 125.732 1.00 77.10  ? 184 PRO B O   1 
ATOM   4243  C CB  . PRO B 1 238 ? 147.954 140.628 123.994 1.00 76.77  ? 184 PRO B CB  1 
ATOM   4244  C CG  . PRO B 1 238 ? 147.421 140.911 122.626 1.00 70.63  ? 184 PRO B CG  1 
ATOM   4245  C CD  . PRO B 1 238 ? 148.262 140.092 121.698 1.00 77.52  ? 184 PRO B CD  1 
ATOM   4246  N N   . GLN B 1 239 ? 149.833 138.108 124.430 1.00 72.44  ? 185 GLN B N   1 
ATOM   4247  C CA  . GLN B 1 239 ? 150.213 137.039 125.343 1.00 69.92  ? 185 GLN B CA  1 
ATOM   4248  C C   . GLN B 1 239 ? 151.587 136.451 125.056 1.00 65.65  ? 185 GLN B C   1 
ATOM   4249  O O   . GLN B 1 239 ? 152.276 136.036 125.993 1.00 61.95  ? 185 GLN B O   1 
ATOM   4250  C CB  . GLN B 1 239 ? 149.170 135.917 125.302 1.00 64.63  ? 185 GLN B CB  1 
ATOM   4251  C CG  . GLN B 1 239 ? 149.325 134.889 126.407 1.00 70.52  ? 185 GLN B CG  1 
ATOM   4252  C CD  . GLN B 1 239 ? 148.270 133.805 126.344 1.00 78.28  ? 185 GLN B CD  1 
ATOM   4253  O OE1 . GLN B 1 239 ? 148.117 133.018 127.279 1.00 72.05  ? 185 GLN B OE1 1 
ATOM   4254  N NE2 . GLN B 1 239 ? 147.537 133.755 125.239 1.00 82.56  ? 185 GLN B NE2 1 
ATOM   4255  N N   . PHE B 1 240 ? 152.003 136.407 123.796 1.00 66.36  ? 186 PHE B N   1 
ATOM   4256  C CA  . PHE B 1 240 ? 153.256 135.782 123.403 1.00 60.88  ? 186 PHE B CA  1 
ATOM   4257  C C   . PHE B 1 240 ? 154.253 136.824 122.914 1.00 59.40  ? 186 PHE B C   1 
ATOM   4258  O O   . PHE B 1 240 ? 153.933 138.002 122.740 1.00 66.71  ? 186 PHE B O   1 
ATOM   4259  C CB  . PHE B 1 240 ? 153.022 134.735 122.309 1.00 57.90  ? 186 PHE B CB  1 
ATOM   4260  C CG  . PHE B 1 240 ? 152.180 133.579 122.746 1.00 58.83  ? 186 PHE B CG  1 
ATOM   4261  C CD1 . PHE B 1 240 ? 150.801 133.637 122.656 1.00 60.89  ? 186 PHE B CD1 1 
ATOM   4262  C CD2 . PHE B 1 240 ? 152.767 132.429 123.244 1.00 57.90  ? 186 PHE B CD2 1 
ATOM   4263  C CE1 . PHE B 1 240 ? 150.024 132.574 123.056 1.00 63.89  ? 186 PHE B CE1 1 
ATOM   4264  C CE2 . PHE B 1 240 ? 151.995 131.362 123.646 1.00 59.81  ? 186 PHE B CE2 1 
ATOM   4265  C CZ  . PHE B 1 240 ? 150.621 131.434 123.551 1.00 62.29  ? 186 PHE B CZ  1 
ATOM   4266  N N   . SER B 1 241 ? 155.483 136.362 122.706 1.00 56.02  ? 187 SER B N   1 
ATOM   4267  C CA  . SER B 1 241 ? 156.531 137.150 122.079 1.00 58.84  ? 187 SER B CA  1 
ATOM   4268  C C   . SER B 1 241 ? 157.287 136.255 121.110 1.00 63.53  ? 187 SER B C   1 
ATOM   4269  O O   . SER B 1 241 ? 157.522 135.079 121.400 1.00 68.58  ? 187 SER B O   1 
ATOM   4270  C CB  . SER B 1 241 ? 157.492 137.740 123.115 1.00 59.32  ? 187 SER B CB  1 
ATOM   4271  O OG  . SER B 1 241 ? 158.227 136.718 123.766 1.00 67.45  ? 187 SER B OG  1 
ATOM   4272  N N   . ILE B 1 242 ? 157.666 136.809 119.963 1.00 59.33  ? 188 ILE B N   1 
ATOM   4273  C CA  . ILE B 1 242 ? 158.353 136.049 118.926 1.00 56.88  ? 188 ILE B CA  1 
ATOM   4274  C C   . ILE B 1 242 ? 159.852 136.159 119.173 1.00 57.84  ? 188 ILE B C   1 
ATOM   4275  O O   . ILE B 1 242 ? 160.436 137.237 119.046 1.00 63.59  ? 188 ILE B O   1 
ATOM   4276  C CB  . ILE B 1 242 ? 157.982 136.541 117.523 1.00 59.15  ? 188 ILE B CB  1 
ATOM   4277  C CG1 . ILE B 1 242 ? 156.499 136.288 117.251 1.00 63.09  ? 188 ILE B CG1 1 
ATOM   4278  C CG2 . ILE B 1 242 ? 158.843 135.856 116.476 1.00 61.31  ? 188 ILE B CG2 1 
ATOM   4279  C CD1 . ILE B 1 242 ? 156.091 136.544 115.825 1.00 79.12  ? 188 ILE B CD1 1 
ATOM   4280  N N   . VAL B 1 243 ? 160.475 135.036 119.525 1.00 56.26  ? 189 VAL B N   1 
ATOM   4281  C CA  . VAL B 1 243 ? 161.906 135.031 119.805 1.00 56.79  ? 189 VAL B CA  1 
ATOM   4282  C C   . VAL B 1 243 ? 162.707 134.890 118.518 1.00 61.45  ? 189 VAL B C   1 
ATOM   4283  O O   . VAL B 1 243 ? 163.632 135.666 118.256 1.00 62.63  ? 189 VAL B O   1 
ATOM   4284  C CB  . VAL B 1 243 ? 162.248 133.914 120.806 1.00 59.66  ? 189 VAL B CB  1 
ATOM   4285  C CG1 . VAL B 1 243 ? 163.722 133.958 121.167 1.00 63.86  ? 189 VAL B CG1 1 
ATOM   4286  C CG2 . VAL B 1 243 ? 161.384 134.040 122.047 1.00 63.67  ? 189 VAL B CG2 1 
ATOM   4287  N N   . GLU B 1 244 ? 162.368 133.900 117.697 1.00 65.00  ? 190 GLU B N   1 
ATOM   4288  C CA  . GLU B 1 244 ? 163.123 133.636 116.483 1.00 67.07  ? 190 GLU B CA  1 
ATOM   4289  C C   . GLU B 1 244 ? 162.197 133.054 115.426 1.00 59.70  ? 190 GLU B C   1 
ATOM   4290  O O   . GLU B 1 244 ? 161.183 132.425 115.742 1.00 63.41  ? 190 GLU B O   1 
ATOM   4291  C CB  . GLU B 1 244 ? 164.291 132.682 116.759 1.00 74.97  ? 190 GLU B CB  1 
ATOM   4292  C CG  . GLU B 1 244 ? 165.353 132.652 115.675 1.00 86.38  ? 190 GLU B CG  1 
ATOM   4293  C CD  . GLU B 1 244 ? 166.547 131.802 116.059 1.00 100.83 ? 190 GLU B CD  1 
ATOM   4294  O OE1 . GLU B 1 244 ? 166.508 131.172 117.136 1.00 102.49 ? 190 GLU B OE1 1 
ATOM   4295  O OE2 . GLU B 1 244 ? 167.527 131.766 115.285 1.00 107.50 ? 190 GLU B OE2 1 
ATOM   4296  N N   . HIS B 1 245 ? 162.551 133.283 114.163 1.00 55.78  ? 191 HIS B N   1 
ATOM   4297  C CA  . HIS B 1 245 ? 161.839 132.693 113.042 1.00 58.62  ? 191 HIS B CA  1 
ATOM   4298  C C   . HIS B 1 245 ? 162.853 132.141 112.053 1.00 57.74  ? 191 HIS B C   1 
ATOM   4299  O O   . HIS B 1 245 ? 163.905 132.744 111.824 1.00 62.50  ? 191 HIS B O   1 
ATOM   4300  C CB  . HIS B 1 245 ? 160.907 133.707 112.359 1.00 56.30  ? 191 HIS B CB  1 
ATOM   4301  C CG  . HIS B 1 245 ? 161.596 134.614 111.388 1.00 60.81  ? 191 HIS B CG  1 
ATOM   4302  N ND1 . HIS B 1 245 ? 162.175 135.806 111.764 1.00 67.47  ? 191 HIS B ND1 1 
ATOM   4303  C CD2 . HIS B 1 245 ? 161.785 134.509 110.051 1.00 60.73  ? 191 HIS B CD2 1 
ATOM   4304  C CE1 . HIS B 1 245 ? 162.698 136.393 110.702 1.00 68.15  ? 191 HIS B CE1 1 
ATOM   4305  N NE2 . HIS B 1 245 ? 162.475 135.626 109.650 1.00 68.11  ? 191 HIS B NE2 1 
ATOM   4306  N N   . ARG B 1 246 ? 162.532 130.986 111.481 1.00 50.89  ? 192 ARG B N   1 
ATOM   4307  C CA  . ARG B 1 246 ? 163.441 130.266 110.601 1.00 43.61  ? 192 ARG B CA  1 
ATOM   4308  C C   . ARG B 1 246 ? 162.725 129.844 109.328 1.00 47.55  ? 192 ARG B C   1 
ATOM   4309  O O   . ARG B 1 246 ? 161.507 129.640 109.315 1.00 52.58  ? 192 ARG B O   1 
ATOM   4310  C CB  . ARG B 1 246 ? 164.026 129.027 111.286 1.00 47.23  ? 192 ARG B CB  1 
ATOM   4311  C CG  . ARG B 1 246 ? 164.858 129.325 112.517 1.00 64.75  ? 192 ARG B CG  1 
ATOM   4312  C CD  . ARG B 1 246 ? 165.376 128.043 113.136 1.00 68.18  ? 192 ARG B CD  1 
ATOM   4313  N NE  . ARG B 1 246 ? 166.073 128.280 114.394 1.00 75.96  ? 192 ARG B NE  1 
ATOM   4314  C CZ  . ARG B 1 246 ? 166.535 127.320 115.182 1.00 81.62  ? 192 ARG B CZ  1 
ATOM   4315  N NH1 . ARG B 1 246 ? 166.392 126.042 114.871 1.00 84.43  ? 192 ARG B NH1 1 
ATOM   4316  N NH2 . ARG B 1 246 ? 167.152 127.649 116.313 1.00 80.36  ? 192 ARG B NH2 1 
ATOM   4317  N N   . LEU B 1 247 ? 163.506 129.703 108.257 1.00 46.26  ? 193 LEU B N   1 
ATOM   4318  C CA  . LEU B 1 247 ? 163.013 129.277 106.955 1.00 41.16  ? 193 LEU B CA  1 
ATOM   4319  C C   . LEU B 1 247 ? 163.809 128.065 106.495 1.00 43.01  ? 193 LEU B C   1 
ATOM   4320  O O   . LEU B 1 247 ? 165.042 128.085 106.522 1.00 51.16  ? 193 LEU B O   1 
ATOM   4321  C CB  . LEU B 1 247 ? 163.131 130.403 105.925 1.00 43.03  ? 193 LEU B CB  1 
ATOM   4322  C CG  . LEU B 1 247 ? 162.465 131.723 106.305 1.00 43.96  ? 193 LEU B CG  1 
ATOM   4323  C CD1 . LEU B 1 247 ? 162.621 132.739 105.188 1.00 44.59  ? 193 LEU B CD1 1 
ATOM   4324  C CD2 . LEU B 1 247 ? 161.005 131.485 106.615 1.00 46.07  ? 193 LEU B CD2 1 
ATOM   4325  N N   . VAL B 1 248 ? 163.105 127.021 106.067 1.00 41.58  ? 194 VAL B N   1 
ATOM   4326  C CA  . VAL B 1 248 ? 163.720 125.773 105.632 1.00 40.46  ? 194 VAL B CA  1 
ATOM   4327  C C   . VAL B 1 248 ? 163.166 125.410 104.263 1.00 46.62  ? 194 VAL B C   1 
ATOM   4328  O O   . VAL B 1 248 ? 161.979 125.612 103.994 1.00 52.54  ? 194 VAL B O   1 
ATOM   4329  C CB  . VAL B 1 248 ? 163.466 124.630 106.640 1.00 43.13  ? 194 VAL B CB  1 
ATOM   4330  C CG1 . VAL B 1 248 ? 164.342 123.431 106.321 1.00 59.77  ? 194 VAL B CG1 1 
ATOM   4331  C CG2 . VAL B 1 248 ? 163.702 125.105 108.066 1.00 54.38  ? 194 VAL B CG2 1 
ATOM   4332  N N   . SER B 1 249 ? 164.023 124.872 103.397 1.00 49.24  ? 195 SER B N   1 
ATOM   4333  C CA  . SER B 1 249 ? 163.625 124.430 102.065 1.00 47.91  ? 195 SER B CA  1 
ATOM   4334  C C   . SER B 1 249 ? 164.147 123.019 101.846 1.00 53.91  ? 195 SER B C   1 
ATOM   4335  O O   . SER B 1 249 ? 165.362 122.800 101.862 1.00 69.85  ? 195 SER B O   1 
ATOM   4336  C CB  . SER B 1 249 ? 164.164 125.373 100.985 1.00 51.51  ? 195 SER B CB  1 
ATOM   4337  O OG  . SER B 1 249 ? 163.769 124.944 99.695  1.00 58.05  ? 195 SER B OG  1 
ATOM   4338  N N   . ARG B 1 250 ? 163.239 122.065 101.642 1.00 50.12  ? 196 ARG B N   1 
ATOM   4339  C CA  . ARG B 1 250 ? 163.638 120.670 101.505 1.00 60.07  ? 196 ARG B CA  1 
ATOM   4340  C C   . ARG B 1 250 ? 162.667 119.946 100.579 1.00 62.73  ? 196 ARG B C   1 
ATOM   4341  O O   . ARG B 1 250 ? 161.766 120.549 99.992  1.00 70.24  ? 196 ARG B O   1 
ATOM   4342  C CB  . ARG B 1 250 ? 163.718 119.990 102.874 1.00 69.86  ? 196 ARG B CB  1 
ATOM   4343  C CG  . ARG B 1 250 ? 162.404 119.949 103.631 1.00 60.69  ? 196 ARG B CG  1 
ATOM   4344  C CD  . ARG B 1 250 ? 162.630 119.550 105.079 1.00 69.26  ? 196 ARG B CD  1 
ATOM   4345  N NE  . ARG B 1 250 ? 161.388 119.219 105.766 1.00 65.06  ? 196 ARG B NE  1 
ATOM   4346  C CZ  . ARG B 1 250 ? 160.949 117.983 105.957 1.00 73.48  ? 196 ARG B CZ  1 
ATOM   4347  N NH1 . ARG B 1 250 ? 161.627 116.934 105.521 1.00 82.45  ? 196 ARG B NH1 1 
ATOM   4348  N NH2 . ARG B 1 250 ? 159.803 117.794 106.605 1.00 69.96  ? 196 ARG B NH2 1 
ATOM   4349  N N   . ASN B 1 251 ? 162.879 118.638 100.436 1.00 61.91  ? 197 ASN B N   1 
ATOM   4350  C CA  . ASN B 1 251 ? 162.019 117.769 99.644  1.00 59.07  ? 197 ASN B CA  1 
ATOM   4351  C C   . ASN B 1 251 ? 161.581 116.586 100.495 1.00 67.77  ? 197 ASN B C   1 
ATOM   4352  O O   . ASN B 1 251 ? 162.382 116.019 101.243 1.00 72.81  ? 197 ASN B O   1 
ATOM   4353  C CB  . ASN B 1 251 ? 162.733 117.267 98.384  1.00 53.68  ? 197 ASN B CB  1 
ATOM   4354  C CG  . ASN B 1 251 ? 163.217 118.397 97.498  1.00 61.51  ? 197 ASN B CG  1 
ATOM   4355  O OD1 . ASN B 1 251 ? 162.658 119.492 97.505  1.00 61.17  ? 197 ASN B OD1 1 
ATOM   4356  N ND2 . ASN B 1 251 ? 164.263 118.133 96.724  1.00 74.02  ? 197 ASN B ND2 1 
ATOM   4357  N N   . VAL B 1 252 ? 160.309 116.213 100.376 1.00 66.58  ? 198 VAL B N   1 
ATOM   4358  C CA  . VAL B 1 252 ? 159.724 115.136 101.166 1.00 68.32  ? 198 VAL B CA  1 
ATOM   4359  C C   . VAL B 1 252 ? 159.216 114.052 100.227 1.00 75.33  ? 198 VAL B C   1 
ATOM   4360  O O   . VAL B 1 252 ? 158.581 114.345 99.210  1.00 76.36  ? 198 VAL B O   1 
ATOM   4361  C CB  . VAL B 1 252 ? 158.589 115.650 102.073 1.00 64.17  ? 198 VAL B CB  1 
ATOM   4362  C CG1 . VAL B 1 252 ? 159.168 116.375 103.271 1.00 67.49  ? 198 VAL B CG1 1 
ATOM   4363  C CG2 . VAL B 1 252 ? 157.673 116.575 101.295 1.00 62.06  ? 198 VAL B CG2 1 
ATOM   4364  N N   . VAL B 1 253 ? 159.492 112.798 100.571 1.00 78.74  ? 199 VAL B N   1 
ATOM   4365  C CA  . VAL B 1 253 ? 159.154 111.658 99.727  1.00 83.37  ? 199 VAL B CA  1 
ATOM   4366  C C   . VAL B 1 253 ? 157.877 111.013 100.245 1.00 89.84  ? 199 VAL B C   1 
ATOM   4367  O O   . VAL B 1 253 ? 157.754 110.731 101.444 1.00 91.32  ? 199 VAL B O   1 
ATOM   4368  C CB  . VAL B 1 253 ? 160.307 110.640 99.682  1.00 81.34  ? 199 VAL B CB  1 
ATOM   4369  C CG1 . VAL B 1 253 ? 159.944 109.464 98.790  1.00 77.78  ? 199 VAL B CG1 1 
ATOM   4370  C CG2 . VAL B 1 253 ? 161.580 111.309 99.195  1.00 70.47  ? 199 VAL B CG2 1 
ATOM   4371  N N   . PHE B 1 254 ? 156.925 110.783 99.343  1.00 91.67  ? 200 PHE B N   1 
ATOM   4372  C CA  . PHE B 1 254 ? 155.702 110.048 99.616  1.00 95.83  ? 200 PHE B CA  1 
ATOM   4373  C C   . PHE B 1 254 ? 155.557 108.949 98.571  1.00 101.37 ? 200 PHE B C   1 
ATOM   4374  O O   . PHE B 1 254 ? 156.362 108.835 97.640  1.00 98.90  ? 200 PHE B O   1 
ATOM   4375  C CB  . PHE B 1 254 ? 154.474 110.968 99.602  1.00 90.12  ? 200 PHE B CB  1 
ATOM   4376  C CG  . PHE B 1 254 ? 154.472 111.997 100.691 1.00 93.11  ? 200 PHE B CG  1 
ATOM   4377  C CD1 . PHE B 1 254 ? 153.945 111.703 101.938 1.00 98.12  ? 200 PHE B CD1 1 
ATOM   4378  C CD2 . PHE B 1 254 ? 154.986 113.262 100.468 1.00 87.05  ? 200 PHE B CD2 1 
ATOM   4379  C CE1 . PHE B 1 254 ? 153.937 112.650 102.942 1.00 98.26  ? 200 PHE B CE1 1 
ATOM   4380  C CE2 . PHE B 1 254 ? 154.981 114.213 101.468 1.00 85.75  ? 200 PHE B CE2 1 
ATOM   4381  C CZ  . PHE B 1 254 ? 154.456 113.906 102.707 1.00 91.49  ? 200 PHE B CZ  1 
ATOM   4382  N N   . ALA B 1 255 ? 154.495 108.152 98.713  1.00 104.38 ? 201 ALA B N   1 
ATOM   4383  C CA  . ALA B 1 255 ? 154.272 107.028 97.812  1.00 104.36 ? 201 ALA B CA  1 
ATOM   4384  C C   . ALA B 1 255 ? 154.136 107.460 96.358  1.00 103.52 ? 201 ALA B C   1 
ATOM   4385  O O   . ALA B 1 255 ? 154.333 106.636 95.458  1.00 101.80 ? 201 ALA B O   1 
ATOM   4386  C CB  . ALA B 1 255 ? 153.027 106.251 98.241  1.00 100.46 ? 201 ALA B CB  1 
ATOM   4387  N N   . THR B 1 256 ? 153.802 108.724 96.106  1.00 105.06 ? 202 THR B N   1 
ATOM   4388  C CA  . THR B 1 256 ? 153.639 109.227 94.750  1.00 105.36 ? 202 THR B CA  1 
ATOM   4389  C C   . THR B 1 256 ? 154.861 109.975 94.233  1.00 97.46  ? 202 THR B C   1 
ATOM   4390  O O   . THR B 1 256 ? 154.838 110.449 93.094  1.00 95.67  ? 202 THR B O   1 
ATOM   4391  C CB  . THR B 1 256 ? 152.410 110.140 94.669  1.00 105.45 ? 202 THR B CB  1 
ATOM   4392  O OG1 . THR B 1 256 ? 152.633 111.315 95.457  1.00 106.06 ? 202 THR B OG1 1 
ATOM   4393  C CG2 . THR B 1 256 ? 151.176 109.417 95.190  1.00 95.36  ? 202 THR B CG2 1 
ATOM   4394  N N   . GLY B 1 257 ? 155.927 110.096 95.031  1.00 92.54  ? 203 GLY B N   1 
ATOM   4395  C CA  . GLY B 1 257 ? 157.135 110.731 94.555  1.00 85.32  ? 203 GLY B CA  1 
ATOM   4396  C C   . GLY B 1 257 ? 157.624 111.782 95.527  1.00 85.48  ? 203 GLY B C   1 
ATOM   4397  O O   . GLY B 1 257 ? 157.199 111.835 96.685  1.00 93.66  ? 203 GLY B O   1 
ATOM   4398  N N   . ALA B 1 258 ? 158.532 112.629 95.051  1.00 76.09  ? 204 ALA B N   1 
ATOM   4399  C CA  . ALA B 1 258 ? 159.148 113.665 95.871  1.00 70.39  ? 204 ALA B CA  1 
ATOM   4400  C C   . ALA B 1 258 ? 158.449 114.997 95.636  1.00 65.26  ? 204 ALA B C   1 
ATOM   4401  O O   . ALA B 1 258 ? 158.220 115.389 94.488  1.00 67.06  ? 204 ALA B O   1 
ATOM   4402  C CB  . ALA B 1 258 ? 160.641 113.788 95.562  1.00 63.65  ? 204 ALA B CB  1 
ATOM   4403  N N   . TYR B 1 259 ? 158.118 115.690 96.726  1.00 62.64  ? 205 TYR B N   1 
ATOM   4404  C CA  . TYR B 1 259 ? 157.432 116.967 96.702  1.00 61.73  ? 205 TYR B CA  1 
ATOM   4405  C C   . TYR B 1 259 ? 158.295 118.051 97.334  1.00 60.12  ? 205 TYR B C   1 
ATOM   4406  O O   . TYR B 1 259 ? 158.965 117.799 98.341  1.00 62.81  ? 205 TYR B O   1 
ATOM   4407  C CB  . TYR B 1 259 ? 156.096 116.893 97.457  1.00 62.22  ? 205 TYR B CB  1 
ATOM   4408  C CG  . TYR B 1 259 ? 155.055 116.006 96.815  1.00 64.39  ? 205 TYR B CG  1 
ATOM   4409  C CD1 . TYR B 1 259 ? 154.215 116.494 95.827  1.00 63.13  ? 205 TYR B CD1 1 
ATOM   4410  C CD2 . TYR B 1 259 ? 154.904 114.684 97.210  1.00 68.75  ? 205 TYR B CD2 1 
ATOM   4411  C CE1 . TYR B 1 259 ? 153.260 115.690 95.241  1.00 64.96  ? 205 TYR B CE1 1 
ATOM   4412  C CE2 . TYR B 1 259 ? 153.950 113.873 96.630  1.00 71.73  ? 205 TYR B CE2 1 
ATOM   4413  C CZ  . TYR B 1 259 ? 153.131 114.381 95.646  1.00 73.29  ? 205 TYR B CZ  1 
ATOM   4414  O OH  . TYR B 1 259 ? 152.178 113.577 95.064  1.00 79.75  ? 205 TYR B OH  1 
ATOM   4415  N N   . PRO B 1 260 ? 158.301 119.257 96.774  1.00 53.04  ? 206 PRO B N   1 
ATOM   4416  C CA  . PRO B 1 260 ? 158.996 120.370 97.426  1.00 51.74  ? 206 PRO B CA  1 
ATOM   4417  C C   . PRO B 1 260 ? 158.287 120.778 98.708  1.00 46.01  ? 206 PRO B C   1 
ATOM   4418  O O   . PRO B 1 260 ? 157.094 120.536 98.895  1.00 50.82  ? 206 PRO B O   1 
ATOM   4419  C CB  . PRO B 1 260 ? 158.943 121.485 96.378  1.00 50.00  ? 206 PRO B CB  1 
ATOM   4420  C CG  . PRO B 1 260 ? 157.741 121.164 95.561  1.00 50.01  ? 206 PRO B CG  1 
ATOM   4421  C CD  . PRO B 1 260 ? 157.650 119.667 95.519  1.00 49.57  ? 206 PRO B CD  1 
ATOM   4422  N N   . ARG B 1 261 ? 159.043 121.411 99.603  1.00 42.18  ? 207 ARG B N   1 
ATOM   4423  C CA  . ARG B 1 261 ? 158.512 121.773 100.909 1.00 43.66  ? 207 ARG B CA  1 
ATOM   4424  C C   . ARG B 1 261 ? 159.235 123.004 101.427 1.00 44.16  ? 207 ARG B C   1 
ATOM   4425  O O   . ARG B 1 261 ? 160.470 123.040 101.449 1.00 54.64  ? 207 ARG B O   1 
ATOM   4426  C CB  . ARG B 1 261 ? 158.668 120.617 101.902 1.00 48.06  ? 207 ARG B CB  1 
ATOM   4427  C CG  . ARG B 1 261 ? 158.223 120.947 103.315 1.00 49.76  ? 207 ARG B CG  1 
ATOM   4428  C CD  . ARG B 1 261 ? 156.716 120.879 103.443 1.00 53.84  ? 207 ARG B CD  1 
ATOM   4429  N NE  . ARG B 1 261 ? 156.229 119.512 103.312 1.00 57.53  ? 207 ARG B NE  1 
ATOM   4430  C CZ  . ARG B 1 261 ? 156.106 118.665 104.325 1.00 57.86  ? 207 ARG B CZ  1 
ATOM   4431  N NH1 . ARG B 1 261 ? 156.418 119.017 105.561 1.00 54.27  ? 207 ARG B NH1 1 
ATOM   4432  N NH2 . ARG B 1 261 ? 155.657 117.435 104.091 1.00 60.33  ? 207 ARG B NH2 1 
ATOM   4433  N N   . LEU B 1 262 ? 158.462 124.003 101.844 1.00 35.44  ? 208 LEU B N   1 
ATOM   4434  C CA  . LEU B 1 262 ? 158.987 125.192 102.499 1.00 38.53  ? 208 LEU B CA  1 
ATOM   4435  C C   . LEU B 1 262 ? 158.397 125.278 103.896 1.00 41.31  ? 208 LEU B C   1 
ATOM   4436  O O   . LEU B 1 262 ? 157.177 125.227 104.062 1.00 43.93  ? 208 LEU B O   1 
ATOM   4437  C CB  . LEU B 1 262 ? 158.657 126.456 101.708 1.00 30.95  ? 208 LEU B CB  1 
ATOM   4438  C CG  . LEU B 1 262 ? 159.270 126.560 100.314 1.00 32.12  ? 208 LEU B CG  1 
ATOM   4439  C CD1 . LEU B 1 262 ? 158.858 127.861 99.659  1.00 35.52  ? 208 LEU B CD1 1 
ATOM   4440  C CD2 . LEU B 1 262 ? 160.776 126.467 100.401 1.00 37.42  ? 208 LEU B CD2 1 
ATOM   4441  N N   . SER B 1 263 ? 159.254 125.405 104.897 1.00 40.47  ? 209 SER B N   1 
ATOM   4442  C CA  . SER B 1 263 ? 158.818 125.473 106.282 1.00 36.59  ? 209 SER B CA  1 
ATOM   4443  C C   . SER B 1 263 ? 159.153 126.840 106.855 1.00 38.00  ? 209 SER B C   1 
ATOM   4444  O O   . SER B 1 263 ? 160.302 127.288 106.774 1.00 44.88  ? 209 SER B O   1 
ATOM   4445  C CB  . SER B 1 263 ? 159.470 124.369 107.115 1.00 45.42  ? 209 SER B CB  1 
ATOM   4446  O OG  . SER B 1 263 ? 159.050 123.091 106.672 1.00 53.00  ? 209 SER B OG  1 
ATOM   4447  N N   . LEU B 1 264 ? 158.149 127.497 107.424 1.00 36.47  ? 210 LEU B N   1 
ATOM   4448  C CA  . LEU B 1 264 ? 158.335 128.718 108.194 1.00 38.45  ? 210 LEU B CA  1 
ATOM   4449  C C   . LEU B 1 264 ? 158.084 128.389 109.657 1.00 46.13  ? 210 LEU B C   1 
ATOM   4450  O O   . LEU B 1 264 ? 157.089 127.741 109.981 1.00 52.33  ? 210 LEU B O   1 
ATOM   4451  C CB  . LEU B 1 264 ? 157.386 129.816 107.711 1.00 38.05  ? 210 LEU B CB  1 
ATOM   4452  C CG  . LEU B 1 264 ? 157.077 130.988 108.642 1.00 43.88  ? 210 LEU B CG  1 
ATOM   4453  C CD1 . LEU B 1 264 ? 158.340 131.740 109.016 1.00 48.45  ? 210 LEU B CD1 1 
ATOM   4454  C CD2 . LEU B 1 264 ? 156.078 131.917 107.976 1.00 33.81  ? 210 LEU B CD2 1 
ATOM   4455  N N   . SER B 1 265 ? 158.984 128.812 110.538 1.00 45.02  ? 211 SER B N   1 
ATOM   4456  C CA  . SER B 1 265 ? 158.908 128.412 111.937 1.00 45.10  ? 211 SER B CA  1 
ATOM   4457  C C   . SER B 1 265 ? 159.031 129.627 112.839 1.00 50.73  ? 211 SER B C   1 
ATOM   4458  O O   . SER B 1 265 ? 159.946 130.436 112.665 1.00 60.51  ? 211 SER B O   1 
ATOM   4459  C CB  . SER B 1 265 ? 160.007 127.403 112.277 1.00 52.70  ? 211 SER B CB  1 
ATOM   4460  O OG  . SER B 1 265 ? 159.994 126.310 111.378 1.00 59.86  ? 211 SER B OG  1 
ATOM   4461  N N   . PHE B 1 266 ? 158.124 129.741 113.807 1.00 52.98  ? 212 PHE B N   1 
ATOM   4462  C CA  . PHE B 1 266 ? 158.210 130.734 114.867 1.00 51.63  ? 212 PHE B CA  1 
ATOM   4463  C C   . PHE B 1 266 ? 158.421 130.034 116.199 1.00 60.24  ? 212 PHE B C   1 
ATOM   4464  O O   . PHE B 1 266 ? 157.786 129.010 116.479 1.00 69.27  ? 212 PHE B O   1 
ATOM   4465  C CB  . PHE B 1 266 ? 156.939 131.580 114.964 1.00 53.10  ? 212 PHE B CB  1 
ATOM   4466  C CG  . PHE B 1 266 ? 156.416 132.055 113.649 1.00 63.06  ? 212 PHE B CG  1 
ATOM   4467  C CD1 . PHE B 1 266 ? 156.957 133.170 113.036 1.00 63.70  ? 212 PHE B CD1 1 
ATOM   4468  C CD2 . PHE B 1 266 ? 155.362 131.402 113.037 1.00 61.99  ? 212 PHE B CD2 1 
ATOM   4469  C CE1 . PHE B 1 266 ? 156.468 133.613 111.829 1.00 64.63  ? 212 PHE B CE1 1 
ATOM   4470  C CE2 . PHE B 1 266 ? 154.868 131.840 111.831 1.00 66.46  ? 212 PHE B CE2 1 
ATOM   4471  C CZ  . PHE B 1 266 ? 155.420 132.947 111.228 1.00 69.38  ? 212 PHE B CZ  1 
ATOM   4472  N N   . ARG B 1 267 ? 159.305 130.590 117.021 1.00 58.49  ? 213 ARG B N   1 
ATOM   4473  C CA  . ARG B 1 267 ? 159.424 130.187 118.415 1.00 59.48  ? 213 ARG B CA  1 
ATOM   4474  C C   . ARG B 1 267 ? 158.776 131.260 119.280 1.00 56.04  ? 213 ARG B C   1 
ATOM   4475  O O   . ARG B 1 267 ? 159.247 132.401 119.318 1.00 61.56  ? 213 ARG B O   1 
ATOM   4476  C CB  . ARG B 1 267 ? 160.883 129.973 118.813 1.00 64.71  ? 213 ARG B CB  1 
ATOM   4477  C CG  . ARG B 1 267 ? 161.054 129.583 120.271 1.00 70.88  ? 213 ARG B CG  1 
ATOM   4478  C CD  . ARG B 1 267 ? 162.307 128.756 120.504 1.00 73.37  ? 213 ARG B CD  1 
ATOM   4479  N NE  . ARG B 1 267 ? 163.531 129.499 120.231 1.00 77.47  ? 213 ARG B NE  1 
ATOM   4480  C CZ  . ARG B 1 267 ? 164.277 129.337 119.147 1.00 82.24  ? 213 ARG B CZ  1 
ATOM   4481  N NH1 . ARG B 1 267 ? 163.954 128.460 118.211 1.00 80.73  ? 213 ARG B NH1 1 
ATOM   4482  N NH2 . ARG B 1 267 ? 165.377 130.070 119.002 1.00 86.06  ? 213 ARG B NH2 1 
ATOM   4483  N N   . LEU B 1 268 ? 157.705 130.890 119.973 1.00 53.43  ? 214 LEU B N   1 
ATOM   4484  C CA  . LEU B 1 268 ? 156.913 131.812 120.774 1.00 57.73  ? 214 LEU B CA  1 
ATOM   4485  C C   . LEU B 1 268 ? 157.205 131.588 122.250 1.00 65.13  ? 214 LEU B C   1 
ATOM   4486  O O   . LEU B 1 268 ? 157.131 130.455 122.737 1.00 72.08  ? 214 LEU B O   1 
ATOM   4487  C CB  . LEU B 1 268 ? 155.418 131.621 120.509 1.00 61.43  ? 214 LEU B CB  1 
ATOM   4488  C CG  . LEU B 1 268 ? 154.909 131.768 119.077 1.00 61.64  ? 214 LEU B CG  1 
ATOM   4489  C CD1 . LEU B 1 268 ? 153.428 131.439 119.018 1.00 56.03  ? 214 LEU B CD1 1 
ATOM   4490  C CD2 . LEU B 1 268 ? 155.164 133.171 118.565 1.00 56.99  ? 214 LEU B CD2 1 
ATOM   4491  N N   . LYS B 1 269 ? 157.525 132.667 122.957 1.00 60.70  ? 215 LYS B N   1 
ATOM   4492  C CA  . LYS B 1 269 ? 157.746 132.631 124.396 1.00 59.78  ? 215 LYS B CA  1 
ATOM   4493  C C   . LYS B 1 269 ? 156.557 133.292 125.080 1.00 60.18  ? 215 LYS B C   1 
ATOM   4494  O O   . LYS B 1 269 ? 156.267 134.466 124.827 1.00 69.15  ? 215 LYS B O   1 
ATOM   4495  C CB  . LYS B 1 269 ? 159.050 133.333 124.771 1.00 64.08  ? 215 LYS B CB  1 
ATOM   4496  C CG  . LYS B 1 269 ? 159.433 133.188 126.231 1.00 67.78  ? 215 LYS B CG  1 
ATOM   4497  C CD  . LYS B 1 269 ? 160.819 133.747 126.496 1.00 81.87  ? 215 LYS B CD  1 
ATOM   4498  C CE  . LYS B 1 269 ? 161.221 133.549 127.948 1.00 96.67  ? 215 LYS B CE  1 
ATOM   4499  N NZ  . LYS B 1 269 ? 162.603 134.030 128.216 1.00 96.00  ? 215 LYS B NZ  1 
ATOM   4500  N N   . ARG B 1 270 ? 155.877 132.541 125.939 1.00 57.41  ? 216 ARG B N   1 
ATOM   4501  C CA  . ARG B 1 270 ? 154.668 133.044 126.575 1.00 59.37  ? 216 ARG B CA  1 
ATOM   4502  C C   . ARG B 1 270 ? 155.011 134.025 127.689 1.00 61.64  ? 216 ARG B C   1 
ATOM   4503  O O   . ARG B 1 270 ? 155.996 133.852 128.411 1.00 60.95  ? 216 ARG B O   1 
ATOM   4504  C CB  . ARG B 1 270 ? 153.842 131.887 127.132 1.00 59.14  ? 216 ARG B CB  1 
ATOM   4505  C CG  . ARG B 1 270 ? 152.452 132.283 127.597 1.00 60.40  ? 216 ARG B CG  1 
ATOM   4506  C CD  . ARG B 1 270 ? 151.723 131.101 128.203 1.00 60.69  ? 216 ARG B CD  1 
ATOM   4507  N NE  . ARG B 1 270 ? 151.650 129.975 127.281 1.00 59.75  ? 216 ARG B NE  1 
ATOM   4508  C CZ  . ARG B 1 270 ? 150.623 129.735 126.479 1.00 62.62  ? 216 ARG B CZ  1 
ATOM   4509  N NH1 . ARG B 1 270 ? 149.557 130.518 126.470 1.00 63.29  ? 216 ARG B NH1 1 
ATOM   4510  N NH2 . ARG B 1 270 ? 150.665 128.681 125.669 1.00 64.45  ? 216 ARG B NH2 1 
ATOM   4511  N N   . ASN B 1 271 ? 154.190 135.063 127.822 1.00 62.13  ? 217 ASN B N   1 
ATOM   4512  C CA  . ASN B 1 271 ? 154.354 136.016 128.904 1.00 62.63  ? 217 ASN B CA  1 
ATOM   4513  C C   . ASN B 1 271 ? 153.640 135.521 130.158 1.00 62.98  ? 217 ASN B C   1 
ATOM   4514  O O   . ASN B 1 271 ? 152.674 134.756 130.097 1.00 66.39  ? 217 ASN B O   1 
ATOM   4515  C CB  . ASN B 1 271 ? 153.831 137.392 128.496 1.00 62.29  ? 217 ASN B CB  1 
ATOM   4516  C CG  . ASN B 1 271 ? 154.565 137.959 127.299 1.00 71.58  ? 217 ASN B CG  1 
ATOM   4517  O OD1 . ASN B 1 271 ? 155.732 137.645 127.066 1.00 68.67  ? 217 ASN B OD1 1 
ATOM   4518  N ND2 . ASN B 1 271 ? 153.883 138.800 126.530 1.00 76.76  ? 217 ASN B ND2 1 
ATOM   4519  N N   . ILE B 1 272 ? 154.131 135.973 131.309 1.00 55.73  ? 218 ILE B N   1 
ATOM   4520  C CA  . ILE B 1 272 ? 153.733 135.414 132.597 1.00 54.65  ? 218 ILE B CA  1 
ATOM   4521  C C   . ILE B 1 272 ? 152.811 136.332 133.388 1.00 59.27  ? 218 ILE B C   1 
ATOM   4522  O O   . ILE B 1 272 ? 152.186 135.868 134.356 1.00 59.32  ? 218 ILE B O   1 
ATOM   4523  C CB  . ILE B 1 272 ? 154.971 135.043 133.443 1.00 56.48  ? 218 ILE B CB  1 
ATOM   4524  C CG1 . ILE B 1 272 ? 154.604 134.078 134.572 1.00 46.79  ? 218 ILE B CG1 1 
ATOM   4525  C CG2 . ILE B 1 272 ? 155.644 136.295 133.978 1.00 64.79  ? 218 ILE B CG2 1 
ATOM   4526  C CD1 . ILE B 1 272 ? 153.891 132.839 134.098 1.00 53.27  ? 218 ILE B CD1 1 
ATOM   4527  N N   . GLY B 1 273 ? 152.681 137.602 133.000 1.00 52.77  ? 219 GLY B N   1 
ATOM   4528  C CA  . GLY B 1 273 ? 151.943 138.549 133.824 1.00 48.62  ? 219 GLY B CA  1 
ATOM   4529  C C   . GLY B 1 273 ? 150.488 138.170 134.026 1.00 54.11  ? 219 GLY B C   1 
ATOM   4530  O O   . GLY B 1 273 ? 149.951 138.303 135.129 1.00 59.23  ? 219 GLY B O   1 
ATOM   4531  N N   . TYR B 1 274 ? 149.829 137.698 132.966 1.00 54.66  ? 220 TYR B N   1 
ATOM   4532  C CA  . TYR B 1 274 ? 148.409 137.371 133.060 1.00 52.02  ? 220 TYR B CA  1 
ATOM   4533  C C   . TYR B 1 274 ? 148.165 136.258 134.072 1.00 54.90  ? 220 TYR B C   1 
ATOM   4534  O O   . TYR B 1 274 ? 147.251 136.343 134.900 1.00 60.83  ? 220 TYR B O   1 
ATOM   4535  C CB  . TYR B 1 274 ? 147.872 136.981 131.683 1.00 52.20  ? 220 TYR B CB  1 
ATOM   4536  C CG  . TYR B 1 274 ? 146.463 136.439 131.700 1.00 57.75  ? 220 TYR B CG  1 
ATOM   4537  C CD1 . TYR B 1 274 ? 145.376 137.277 131.900 1.00 59.74  ? 220 TYR B CD1 1 
ATOM   4538  C CD2 . TYR B 1 274 ? 146.220 135.088 131.503 1.00 63.07  ? 220 TYR B CD2 1 
ATOM   4539  C CE1 . TYR B 1 274 ? 144.088 136.782 131.912 1.00 61.31  ? 220 TYR B CE1 1 
ATOM   4540  C CE2 . TYR B 1 274 ? 144.936 134.586 131.514 1.00 63.51  ? 220 TYR B CE2 1 
ATOM   4541  C CZ  . TYR B 1 274 ? 143.875 135.436 131.717 1.00 64.81  ? 220 TYR B CZ  1 
ATOM   4542  O OH  . TYR B 1 274 ? 142.595 134.936 131.727 1.00 74.00  ? 220 TYR B OH  1 
ATOM   4543  N N   . PHE B 1 275 ? 148.986 135.210 134.031 1.00 53.53  ? 221 PHE B N   1 
ATOM   4544  C CA  . PHE B 1 275 ? 148.838 134.111 134.976 1.00 50.91  ? 221 PHE B CA  1 
ATOM   4545  C C   . PHE B 1 275 ? 149.319 134.492 136.368 1.00 49.39  ? 221 PHE B C   1 
ATOM   4546  O O   . PHE B 1 275 ? 148.781 133.994 137.363 1.00 51.20  ? 221 PHE B O   1 
ATOM   4547  C CB  . PHE B 1 275 ? 149.591 132.885 134.467 1.00 48.57  ? 221 PHE B CB  1 
ATOM   4548  C CG  . PHE B 1 275 ? 149.283 132.547 133.041 1.00 49.14  ? 221 PHE B CG  1 
ATOM   4549  C CD1 . PHE B 1 275 ? 148.203 131.744 132.726 1.00 53.84  ? 221 PHE B CD1 1 
ATOM   4550  C CD2 . PHE B 1 275 ? 150.064 133.045 132.012 1.00 51.98  ? 221 PHE B CD2 1 
ATOM   4551  C CE1 . PHE B 1 275 ? 147.913 131.438 131.415 1.00 62.00  ? 221 PHE B CE1 1 
ATOM   4552  C CE2 . PHE B 1 275 ? 149.779 132.741 130.700 1.00 60.06  ? 221 PHE B CE2 1 
ATOM   4553  C CZ  . PHE B 1 275 ? 148.702 131.936 130.400 1.00 61.96  ? 221 PHE B CZ  1 
ATOM   4554  N N   . ILE B 1 276 ? 150.329 135.360 136.456 1.00 49.00  ? 222 ILE B N   1 
ATOM   4555  C CA  . ILE B 1 276 ? 150.774 135.857 137.754 1.00 47.65  ? 222 ILE B CA  1 
ATOM   4556  C C   . ILE B 1 276 ? 149.640 136.588 138.458 1.00 47.41  ? 222 ILE B C   1 
ATOM   4557  O O   . ILE B 1 276 ? 149.394 136.383 139.653 1.00 51.02  ? 222 ILE B O   1 
ATOM   4558  C CB  . ILE B 1 276 ? 152.011 136.758 137.584 1.00 42.86  ? 222 ILE B CB  1 
ATOM   4559  C CG1 . ILE B 1 276 ? 153.268 135.910 137.397 1.00 45.07  ? 222 ILE B CG1 1 
ATOM   4560  C CG2 . ILE B 1 276 ? 152.171 137.683 138.776 1.00 44.24  ? 222 ILE B CG2 1 
ATOM   4561  C CD1 . ILE B 1 276 ? 153.643 135.106 138.615 1.00 51.50  ? 222 ILE B CD1 1 
ATOM   4562  N N   . LEU B 1 277 ? 148.924 137.440 137.730 1.00 52.33  ? 223 LEU B N   1 
ATOM   4563  C CA  . LEU B 1 277 ? 147.858 138.240 138.315 1.00 55.29  ? 223 LEU B CA  1 
ATOM   4564  C C   . LEU B 1 277 ? 146.504 137.545 138.304 1.00 57.72  ? 223 LEU B C   1 
ATOM   4565  O O   . LEU B 1 277 ? 145.548 138.086 138.871 1.00 66.26  ? 223 LEU B O   1 
ATOM   4566  C CB  . LEU B 1 277 ? 147.745 139.576 137.576 1.00 56.41  ? 223 LEU B CB  1 
ATOM   4567  C CG  . LEU B 1 277 ? 149.018 140.421 137.557 1.00 52.75  ? 223 LEU B CG  1 
ATOM   4568  C CD1 . LEU B 1 277 ? 148.983 141.402 136.402 1.00 50.72  ? 223 LEU B CD1 1 
ATOM   4569  C CD2 . LEU B 1 277 ? 149.191 141.149 138.880 1.00 52.22  ? 223 LEU B CD2 1 
ATOM   4570  N N   . GLN B 1 278 ? 146.389 136.377 137.675 1.00 51.30  ? 224 GLN B N   1 
ATOM   4571  C CA  . GLN B 1 278 ? 145.104 135.697 137.565 1.00 54.41  ? 224 GLN B CA  1 
ATOM   4572  C C   . GLN B 1 278 ? 145.026 134.405 138.367 1.00 57.66  ? 224 GLN B C   1 
ATOM   4573  O O   . GLN B 1 278 ? 143.958 134.077 138.891 1.00 64.88  ? 224 GLN B O   1 
ATOM   4574  C CB  . GLN B 1 278 ? 144.797 135.396 136.095 1.00 60.73  ? 224 GLN B CB  1 
ATOM   4575  C CG  . GLN B 1 278 ? 143.327 135.158 135.807 1.00 64.71  ? 224 GLN B CG  1 
ATOM   4576  C CD  . GLN B 1 278 ? 142.501 136.424 135.926 1.00 75.19  ? 224 GLN B CD  1 
ATOM   4577  O OE1 . GLN B 1 278 ? 142.999 137.528 135.703 1.00 76.54  ? 224 GLN B OE1 1 
ATOM   4578  N NE2 . GLN B 1 278 ? 141.232 136.271 136.284 1.00 73.39  ? 224 GLN B NE2 1 
ATOM   4579  N N   . THR B 1 279 ? 146.120 133.655 138.468 1.00 59.28  ? 225 THR B N   1 
ATOM   4580  C CA  . THR B 1 279 ? 146.109 132.361 139.144 1.00 54.81  ? 225 THR B CA  1 
ATOM   4581  C C   . THR B 1 279 ? 147.047 132.280 140.337 1.00 51.77  ? 225 THR B C   1 
ATOM   4582  O O   . THR B 1 279 ? 146.637 131.813 141.401 1.00 52.33  ? 225 THR B O   1 
ATOM   4583  C CB  . THR B 1 279 ? 146.468 131.247 138.153 1.00 52.45  ? 225 THR B CB  1 
ATOM   4584  O OG1 . THR B 1 279 ? 147.784 131.476 137.636 1.00 60.13  ? 225 THR B OG1 1 
ATOM   4585  C CG2 . THR B 1 279 ? 145.476 131.218 137.001 1.00 51.99  ? 225 THR B CG2 1 
ATOM   4586  N N   . TYR B 1 280 ? 148.300 132.717 140.191 1.00 50.67  ? 226 TYR B N   1 
ATOM   4587  C CA  . TYR B 1 280 ? 149.264 132.579 141.279 1.00 46.49  ? 226 TYR B CA  1 
ATOM   4588  C C   . TYR B 1 280 ? 148.917 133.490 142.452 1.00 53.45  ? 226 TYR B C   1 
ATOM   4589  O O   . TYR B 1 280 ? 148.910 133.055 143.611 1.00 61.09  ? 226 TYR B O   1 
ATOM   4590  C CB  . TYR B 1 280 ? 150.675 132.872 140.768 1.00 39.16  ? 226 TYR B CB  1 
ATOM   4591  C CG  . TYR B 1 280 ? 151.234 131.802 139.858 1.00 44.40  ? 226 TYR B CG  1 
ATOM   4592  C CD1 . TYR B 1 280 ? 151.071 131.875 138.482 1.00 50.14  ? 226 TYR B CD1 1 
ATOM   4593  C CD2 . TYR B 1 280 ? 151.925 130.718 140.376 1.00 46.50  ? 226 TYR B CD2 1 
ATOM   4594  C CE1 . TYR B 1 280 ? 151.582 130.897 137.650 1.00 49.95  ? 226 TYR B CE1 1 
ATOM   4595  C CE2 . TYR B 1 280 ? 152.438 129.737 139.552 1.00 51.03  ? 226 TYR B CE2 1 
ATOM   4596  C CZ  . TYR B 1 280 ? 152.265 129.832 138.191 1.00 51.86  ? 226 TYR B CZ  1 
ATOM   4597  O OH  . TYR B 1 280 ? 152.775 128.855 137.370 1.00 59.75  ? 226 TYR B OH  1 
ATOM   4598  N N   . MET B 1 281 ? 148.636 134.765 142.169 1.00 55.01  ? 227 MET B N   1 
ATOM   4599  C CA  . MET B 1 281 ? 148.331 135.716 143.237 1.00 50.38  ? 227 MET B CA  1 
ATOM   4600  C C   . MET B 1 281 ? 147.111 135.311 144.055 1.00 51.79  ? 227 MET B C   1 
ATOM   4601  O O   . MET B 1 281 ? 147.173 135.381 145.295 1.00 55.14  ? 227 MET B O   1 
ATOM   4602  C CB  . MET B 1 281 ? 148.179 137.119 142.643 1.00 52.72  ? 227 MET B CB  1 
ATOM   4603  C CG  . MET B 1 281 ? 147.937 138.203 143.679 1.00 59.84  ? 227 MET B CG  1 
ATOM   4604  S SD  . MET B 1 281 ? 149.428 138.644 144.591 1.00 95.01  ? 227 MET B SD  1 
ATOM   4605  C CE  . MET B 1 281 ? 150.391 139.430 143.304 1.00 64.34  ? 227 MET B CE  1 
ATOM   4606  N N   . PRO B 1 282 ? 145.978 134.913 143.455 1.00 55.45  ? 228 PRO B N   1 
ATOM   4607  C CA  . PRO B 1 282 ? 144.863 134.431 144.286 1.00 58.69  ? 228 PRO B CA  1 
ATOM   4608  C C   . PRO B 1 282 ? 145.229 133.242 145.155 1.00 57.78  ? 228 PRO B C   1 
ATOM   4609  O O   . PRO B 1 282 ? 144.789 133.167 146.307 1.00 63.10  ? 228 PRO B O   1 
ATOM   4610  C CB  . PRO B 1 282 ? 143.790 134.069 143.251 1.00 54.30  ? 228 PRO B CB  1 
ATOM   4611  C CG  . PRO B 1 282 ? 144.096 134.915 142.088 1.00 53.71  ? 228 PRO B CG  1 
ATOM   4612  C CD  . PRO B 1 282 ? 145.589 134.989 142.035 1.00 55.93  ? 228 PRO B CD  1 
ATOM   4613  N N   . SER B 1 283 ? 146.035 132.313 144.639 1.00 51.28  ? 229 SER B N   1 
ATOM   4614  C CA  . SER B 1 283 ? 146.433 131.160 145.438 1.00 52.76  ? 229 SER B CA  1 
ATOM   4615  C C   . SER B 1 283 ? 147.274 131.586 146.634 1.00 54.56  ? 229 SER B C   1 
ATOM   4616  O O   . SER B 1 283 ? 147.076 131.091 147.751 1.00 59.93  ? 229 SER B O   1 
ATOM   4617  C CB  . SER B 1 283 ? 147.195 130.160 144.571 1.00 50.67  ? 229 SER B CB  1 
ATOM   4618  O OG  . SER B 1 283 ? 146.398 129.729 143.485 1.00 53.43  ? 229 SER B OG  1 
ATOM   4619  N N   . ILE B 1 284 ? 148.208 132.515 146.425 1.00 50.27  ? 230 ILE B N   1 
ATOM   4620  C CA  . ILE B 1 284 ? 149.029 132.997 147.533 1.00 55.67  ? 230 ILE B CA  1 
ATOM   4621  C C   . ILE B 1 284 ? 148.167 133.721 148.562 1.00 60.86  ? 230 ILE B C   1 
ATOM   4622  O O   . ILE B 1 284 ? 148.351 133.561 149.778 1.00 62.65  ? 230 ILE B O   1 
ATOM   4623  C CB  . ILE B 1 284 ? 150.163 133.895 147.007 1.00 48.19  ? 230 ILE B CB  1 
ATOM   4624  C CG1 . ILE B 1 284 ? 151.068 133.101 146.065 1.00 49.28  ? 230 ILE B CG1 1 
ATOM   4625  C CG2 . ILE B 1 284 ? 150.966 134.466 148.160 1.00 49.54  ? 230 ILE B CG2 1 
ATOM   4626  C CD1 . ILE B 1 284 ? 152.202 133.911 145.481 1.00 59.35  ? 230 ILE B CD1 1 
ATOM   4627  N N   . LEU B 1 285 ? 147.215 134.532 148.094 1.00 58.83  ? 231 LEU B N   1 
ATOM   4628  C CA  . LEU B 1 285 ? 146.340 135.250 149.016 1.00 53.25  ? 231 LEU B CA  1 
ATOM   4629  C C   . LEU B 1 285 ? 145.492 134.288 149.837 1.00 56.29  ? 231 LEU B C   1 
ATOM   4630  O O   . LEU B 1 285 ? 145.316 134.483 151.045 1.00 64.69  ? 231 LEU B O   1 
ATOM   4631  C CB  . LEU B 1 285 ? 145.454 136.228 148.247 1.00 54.51  ? 231 LEU B CB  1 
ATOM   4632  C CG  . LEU B 1 285 ? 146.189 137.381 147.564 1.00 66.45  ? 231 LEU B CG  1 
ATOM   4633  C CD1 . LEU B 1 285 ? 145.227 138.229 146.750 1.00 67.51  ? 231 LEU B CD1 1 
ATOM   4634  C CD2 . LEU B 1 285 ? 146.922 138.228 148.591 1.00 69.78  ? 231 LEU B CD2 1 
ATOM   4635  N N   . ILE B 1 286 ? 144.960 133.243 149.202 1.00 51.67  ? 232 ILE B N   1 
ATOM   4636  C CA  . ILE B 1 286 ? 144.155 132.272 149.936 1.00 50.05  ? 232 ILE B CA  1 
ATOM   4637  C C   . ILE B 1 286 ? 145.019 131.502 150.926 1.00 52.75  ? 232 ILE B C   1 
ATOM   4638  O O   . ILE B 1 286 ? 144.576 131.172 152.032 1.00 52.68  ? 232 ILE B O   1 
ATOM   4639  C CB  . ILE B 1 286 ? 143.422 131.333 148.962 1.00 54.08  ? 232 ILE B CB  1 
ATOM   4640  C CG1 . ILE B 1 286 ? 142.472 132.130 148.069 1.00 51.89  ? 232 ILE B CG1 1 
ATOM   4641  C CG2 . ILE B 1 286 ? 142.648 130.272 149.720 1.00 59.02  ? 232 ILE B CG2 1 
ATOM   4642  C CD1 . ILE B 1 286 ? 141.535 133.035 148.829 1.00 49.68  ? 232 ILE B CD1 1 
ATOM   4643  N N   . THR B 1 287 ? 146.269 131.213 150.556 1.00 51.62  ? 233 THR B N   1 
ATOM   4644  C CA  . THR B 1 287 ? 147.169 130.541 151.489 1.00 52.70  ? 233 THR B CA  1 
ATOM   4645  C C   . THR B 1 287 ? 147.433 131.404 152.719 1.00 57.69  ? 233 THR B C   1 
ATOM   4646  O O   . THR B 1 287 ? 147.421 130.907 153.853 1.00 63.13  ? 233 THR B O   1 
ATOM   4647  C CB  . THR B 1 287 ? 148.479 130.184 150.789 1.00 50.64  ? 233 THR B CB  1 
ATOM   4648  O OG1 . THR B 1 287 ? 148.191 129.471 149.582 1.00 50.30  ? 233 THR B OG1 1 
ATOM   4649  C CG2 . THR B 1 287 ? 149.333 129.309 151.683 1.00 59.61  ? 233 THR B CG2 1 
ATOM   4650  N N   . ILE B 1 288 ? 147.663 132.703 152.519 1.00 52.29  ? 234 ILE B N   1 
ATOM   4651  C CA  . ILE B 1 288 ? 147.873 133.596 153.657 1.00 52.26  ? 234 ILE B CA  1 
ATOM   4652  C C   . ILE B 1 288 ? 146.604 133.704 154.499 1.00 55.32  ? 234 ILE B C   1 
ATOM   4653  O O   . ILE B 1 288 ? 146.660 133.734 155.737 1.00 61.74  ? 234 ILE B O   1 
ATOM   4654  C CB  . ILE B 1 288 ? 148.363 134.972 153.174 1.00 51.22  ? 234 ILE B CB  1 
ATOM   4655  C CG1 . ILE B 1 288 ? 149.712 134.830 152.469 1.00 53.13  ? 234 ILE B CG1 1 
ATOM   4656  C CG2 . ILE B 1 288 ? 148.474 135.939 154.338 1.00 56.42  ? 234 ILE B CG2 1 
ATOM   4657  C CD1 . ILE B 1 288 ? 150.290 136.136 151.978 1.00 58.89  ? 234 ILE B CD1 1 
ATOM   4658  N N   . LEU B 1 289 ? 145.443 133.770 153.844 1.00 51.56  ? 235 LEU B N   1 
ATOM   4659  C CA  . LEU B 1 289 ? 144.176 133.795 154.568 1.00 49.69  ? 235 LEU B CA  1 
ATOM   4660  C C   . LEU B 1 289 ? 144.012 132.550 155.432 1.00 55.38  ? 235 LEU B C   1 
ATOM   4661  O O   . LEU B 1 289 ? 143.514 132.628 156.560 1.00 60.62  ? 235 LEU B O   1 
ATOM   4662  C CB  . LEU B 1 289 ? 143.018 133.922 153.579 1.00 47.79  ? 235 LEU B CB  1 
ATOM   4663  C CG  . LEU B 1 289 ? 141.602 134.056 154.138 1.00 48.23  ? 235 LEU B CG  1 
ATOM   4664  C CD1 . LEU B 1 289 ? 141.454 135.363 154.892 1.00 55.10  ? 235 LEU B CD1 1 
ATOM   4665  C CD2 . LEU B 1 289 ? 140.578 133.962 153.019 1.00 42.78  ? 235 LEU B CD2 1 
ATOM   4666  N N   . SER B 1 290 ? 144.413 131.389 154.910 1.00 56.40  ? 236 SER B N   1 
ATOM   4667  C CA  . SER B 1 290 ? 144.394 130.169 155.711 1.00 58.22  ? 236 SER B CA  1 
ATOM   4668  C C   . SER B 1 290 ? 145.364 130.266 156.881 1.00 58.38  ? 236 SER B C   1 
ATOM   4669  O O   . SER B 1 290 ? 145.054 129.822 157.992 1.00 61.66  ? 236 SER B O   1 
ATOM   4670  C CB  . SER B 1 290 ? 144.727 128.960 154.839 1.00 59.10  ? 236 SER B CB  1 
ATOM   4671  O OG  . SER B 1 290 ? 146.051 129.039 154.345 1.00 61.55  ? 236 SER B OG  1 
ATOM   4672  N N   . TRP B 1 291 ? 146.549 130.835 156.645 1.00 57.92  ? 237 TRP B N   1 
ATOM   4673  C CA  . TRP B 1 291 ? 147.516 131.013 157.726 1.00 60.56  ? 237 TRP B CA  1 
ATOM   4674  C C   . TRP B 1 291 ? 146.957 131.875 158.846 1.00 63.98  ? 237 TRP B C   1 
ATOM   4675  O O   . TRP B 1 291 ? 147.320 131.685 160.013 1.00 66.10  ? 237 TRP B O   1 
ATOM   4676  C CB  . TRP B 1 291 ? 148.797 131.655 157.205 1.00 57.44  ? 237 TRP B CB  1 
ATOM   4677  C CG  . TRP B 1 291 ? 149.536 130.846 156.217 1.00 60.66  ? 237 TRP B CG  1 
ATOM   4678  C CD1 . TRP B 1 291 ? 149.275 129.563 155.843 1.00 54.91  ? 237 TRP B CD1 1 
ATOM   4679  C CD2 . TRP B 1 291 ? 150.673 131.265 155.463 1.00 65.18  ? 237 TRP B CD2 1 
ATOM   4680  N NE1 . TRP B 1 291 ? 150.183 129.156 154.899 1.00 54.90  ? 237 TRP B NE1 1 
ATOM   4681  C CE2 . TRP B 1 291 ? 151.052 130.185 154.649 1.00 63.91  ? 237 TRP B CE2 1 
ATOM   4682  C CE3 . TRP B 1 291 ? 151.408 132.452 155.398 1.00 62.76  ? 237 TRP B CE3 1 
ATOM   4683  C CZ2 . TRP B 1 291 ? 152.130 130.255 153.781 1.00 66.61  ? 237 TRP B CZ2 1 
ATOM   4684  C CZ3 . TRP B 1 291 ? 152.480 132.518 154.535 1.00 63.91  ? 237 TRP B CZ3 1 
ATOM   4685  C CH2 . TRP B 1 291 ? 152.832 131.427 153.738 1.00 66.44  ? 237 TRP B CH2 1 
ATOM   4686  N N   . VAL B 1 292 ? 146.103 132.843 158.502 1.00 64.09  ? 238 VAL B N   1 
ATOM   4687  C CA  . VAL B 1 292 ? 145.572 133.795 159.481 1.00 64.15  ? 238 VAL B CA  1 
ATOM   4688  C C   . VAL B 1 292 ? 145.055 133.100 160.736 1.00 67.21  ? 238 VAL B C   1 
ATOM   4689  O O   . VAL B 1 292 ? 145.175 133.634 161.845 1.00 69.24  ? 238 VAL B O   1 
ATOM   4690  C CB  . VAL B 1 292 ? 144.477 134.664 158.826 1.00 59.04  ? 238 VAL B CB  1 
ATOM   4691  C CG1 . VAL B 1 292 ? 143.750 135.497 159.864 1.00 49.91  ? 238 VAL B CG1 1 
ATOM   4692  C CG2 . VAL B 1 292 ? 145.084 135.566 157.770 1.00 62.45  ? 238 VAL B CG2 1 
ATOM   4693  N N   . SER B 1 293 ? 144.508 131.890 160.595 1.00 69.00  ? 239 SER B N   1 
ATOM   4694  C CA  . SER B 1 293 ? 143.879 131.205 161.720 1.00 70.11  ? 239 SER B CA  1 
ATOM   4695  C C   . SER B 1 293 ? 144.857 130.829 162.825 1.00 71.48  ? 239 SER B C   1 
ATOM   4696  O O   . SER B 1 293 ? 144.411 130.486 163.924 1.00 79.45  ? 239 SER B O   1 
ATOM   4697  C CB  . SER B 1 293 ? 143.161 129.944 161.233 1.00 74.86  ? 239 SER B CB  1 
ATOM   4698  O OG  . SER B 1 293 ? 144.080 128.988 160.736 1.00 79.13  ? 239 SER B OG  1 
ATOM   4699  N N   . PHE B 1 294 ? 146.167 130.887 162.572 1.00 73.43  ? 240 PHE B N   1 
ATOM   4700  C CA  . PHE B 1 294 ? 147.130 130.487 163.593 1.00 75.51  ? 240 PHE B CA  1 
ATOM   4701  C C   . PHE B 1 294 ? 147.239 131.518 164.708 1.00 77.50  ? 240 PHE B C   1 
ATOM   4702  O O   . PHE B 1 294 ? 147.538 131.159 165.852 1.00 75.94  ? 240 PHE B O   1 
ATOM   4703  C CB  . PHE B 1 294 ? 148.498 130.245 162.960 1.00 70.73  ? 240 PHE B CB  1 
ATOM   4704  C CG  . PHE B 1 294 ? 148.517 129.107 161.986 1.00 71.40  ? 240 PHE B CG  1 
ATOM   4705  C CD1 . PHE B 1 294 ? 147.667 128.026 162.150 1.00 73.80  ? 240 PHE B CD1 1 
ATOM   4706  C CD2 . PHE B 1 294 ? 149.377 129.119 160.904 1.00 67.91  ? 240 PHE B CD2 1 
ATOM   4707  C CE1 . PHE B 1 294 ? 147.679 126.978 161.256 1.00 73.03  ? 240 PHE B CE1 1 
ATOM   4708  C CE2 . PHE B 1 294 ? 149.393 128.074 160.006 1.00 67.89  ? 240 PHE B CE2 1 
ATOM   4709  C CZ  . PHE B 1 294 ? 148.543 127.002 160.182 1.00 67.84  ? 240 PHE B CZ  1 
ATOM   4710  N N   . TRP B 1 295 ? 147.011 132.794 164.401 1.00 78.77  ? 241 TRP B N   1 
ATOM   4711  C CA  . TRP B 1 295 ? 147.020 133.824 165.430 1.00 76.53  ? 241 TRP B CA  1 
ATOM   4712  C C   . TRP B 1 295 ? 145.693 133.934 166.165 1.00 75.05  ? 241 TRP B C   1 
ATOM   4713  O O   . TRP B 1 295 ? 145.631 134.607 167.199 1.00 84.36  ? 241 TRP B O   1 
ATOM   4714  C CB  . TRP B 1 295 ? 147.390 135.179 164.821 1.00 76.32  ? 241 TRP B CB  1 
ATOM   4715  C CG  . TRP B 1 295 ? 148.859 135.336 164.571 1.00 75.72  ? 241 TRP B CG  1 
ATOM   4716  C CD1 . TRP B 1 295 ? 149.816 135.648 165.490 1.00 76.12  ? 241 TRP B CD1 1 
ATOM   4717  C CD2 . TRP B 1 295 ? 149.540 135.190 163.319 1.00 73.36  ? 241 TRP B CD2 1 
ATOM   4718  N NE1 . TRP B 1 295 ? 151.050 135.704 164.892 1.00 71.61  ? 241 TRP B NE1 1 
ATOM   4719  C CE2 . TRP B 1 295 ? 150.907 135.427 163.558 1.00 72.36  ? 241 TRP B CE2 1 
ATOM   4720  C CE3 . TRP B 1 295 ? 149.125 134.882 162.021 1.00 76.96  ? 241 TRP B CE3 1 
ATOM   4721  C CZ2 . TRP B 1 295 ? 151.863 135.365 162.547 1.00 77.69  ? 241 TRP B CZ2 1 
ATOM   4722  C CZ3 . TRP B 1 295 ? 150.075 134.821 161.019 1.00 79.51  ? 241 TRP B CZ3 1 
ATOM   4723  C CH2 . TRP B 1 295 ? 151.428 135.062 161.287 1.00 78.90  ? 241 TRP B CH2 1 
ATOM   4724  N N   . ILE B 1 296 ? 144.636 133.299 165.661 1.00 69.42  ? 242 ILE B N   1 
ATOM   4725  C CA  . ILE B 1 296 ? 143.378 133.241 166.392 1.00 67.90  ? 242 ILE B CA  1 
ATOM   4726  C C   . ILE B 1 296 ? 143.513 132.246 167.535 1.00 84.93  ? 242 ILE B C   1 
ATOM   4727  O O   . ILE B 1 296 ? 144.020 131.132 167.351 1.00 91.22  ? 242 ILE B O   1 
ATOM   4728  C CB  . ILE B 1 296 ? 142.225 132.860 165.454 1.00 62.64  ? 242 ILE B CB  1 
ATOM   4729  C CG1 . ILE B 1 296 ? 142.025 133.938 164.390 1.00 61.22  ? 242 ILE B CG1 1 
ATOM   4730  C CG2 . ILE B 1 296 ? 140.944 132.660 166.241 1.00 74.55  ? 242 ILE B CG2 1 
ATOM   4731  C CD1 . ILE B 1 296 ? 141.545 135.254 164.949 1.00 73.23  ? 242 ILE B CD1 1 
ATOM   4732  N N   . ASN B 1 297 ? 143.071 132.646 168.725 1.00 92.65  ? 243 ASN B N   1 
ATOM   4733  C CA  . ASN B 1 297 ? 143.102 131.742 169.866 1.00 104.00 ? 243 ASN B CA  1 
ATOM   4734  C C   . ASN B 1 297 ? 142.225 130.528 169.592 1.00 105.66 ? 243 ASN B C   1 
ATOM   4735  O O   . ASN B 1 297 ? 141.113 130.649 169.071 1.00 105.17 ? 243 ASN B O   1 
ATOM   4736  C CB  . ASN B 1 297 ? 142.633 132.462 171.128 1.00 109.62 ? 243 ASN B CB  1 
ATOM   4737  C CG  . ASN B 1 297 ? 142.861 131.643 172.380 1.00 114.24 ? 243 ASN B CG  1 
ATOM   4738  O OD1 . ASN B 1 297 ? 143.736 130.779 172.418 1.00 109.74 ? 243 ASN B OD1 1 
ATOM   4739  N ND2 . ASN B 1 297 ? 142.072 131.908 173.414 1.00 121.06 ? 243 ASN B ND2 1 
ATOM   4740  N N   . TYR B 1 298 ? 142.733 129.346 169.950 1.00 106.89 ? 244 TYR B N   1 
ATOM   4741  C CA  . TYR B 1 298 ? 142.072 128.103 169.568 1.00 109.00 ? 244 TYR B CA  1 
ATOM   4742  C C   . TYR B 1 298 ? 140.728 127.899 170.252 1.00 112.80 ? 244 TYR B C   1 
ATOM   4743  O O   . TYR B 1 298 ? 139.985 126.998 169.849 1.00 112.61 ? 244 TYR B O   1 
ATOM   4744  C CB  . TYR B 1 298 ? 142.983 126.903 169.845 1.00 110.36 ? 244 TYR B CB  1 
ATOM   4745  C CG  . TYR B 1 298 ? 143.641 126.894 171.206 1.00 114.17 ? 244 TYR B CG  1 
ATOM   4746  C CD1 . TYR B 1 298 ? 142.992 126.360 172.310 1.00 116.76 ? 244 TYR B CD1 1 
ATOM   4747  C CD2 . TYR B 1 298 ? 144.921 127.401 171.381 1.00 112.86 ? 244 TYR B CD2 1 
ATOM   4748  C CE1 . TYR B 1 298 ? 143.595 126.343 173.554 1.00 120.86 ? 244 TYR B CE1 1 
ATOM   4749  C CE2 . TYR B 1 298 ? 145.532 127.389 172.620 1.00 118.71 ? 244 TYR B CE2 1 
ATOM   4750  C CZ  . TYR B 1 298 ? 144.864 126.858 173.702 1.00 125.56 ? 244 TYR B CZ  1 
ATOM   4751  O OH  . TYR B 1 298 ? 145.468 126.844 174.939 1.00 130.36 ? 244 TYR B OH  1 
ATOM   4752  N N   . ASP B 1 299 ? 140.394 128.696 171.269 1.00 113.45 ? 245 ASP B N   1 
ATOM   4753  C CA  . ASP B 1 299 ? 139.067 128.591 171.861 1.00 116.99 ? 245 ASP B CA  1 
ATOM   4754  C C   . ASP B 1 299 ? 137.995 129.211 170.975 1.00 119.12 ? 245 ASP B C   1 
ATOM   4755  O O   . ASP B 1 299 ? 136.811 128.899 171.145 1.00 117.73 ? 245 ASP B O   1 
ATOM   4756  C CB  . ASP B 1 299 ? 139.046 129.238 173.247 1.00 118.80 ? 245 ASP B CB  1 
ATOM   4757  C CG  . ASP B 1 299 ? 139.088 130.750 173.188 1.00 120.18 ? 245 ASP B CG  1 
ATOM   4758  O OD1 . ASP B 1 299 ? 139.779 131.298 172.304 1.00 119.14 ? 245 ASP B OD1 1 
ATOM   4759  O OD2 . ASP B 1 299 ? 138.425 131.393 174.030 1.00 123.31 ? 245 ASP B OD2 1 
ATOM   4760  N N   . ALA B 1 300 ? 138.380 130.076 170.035 1.00 116.28 ? 246 ALA B N   1 
ATOM   4761  C CA  . ALA B 1 300 ? 137.447 130.644 169.061 1.00 104.66 ? 246 ALA B CA  1 
ATOM   4762  C C   . ALA B 1 300 ? 137.238 129.617 167.952 1.00 99.56  ? 246 ALA B C   1 
ATOM   4763  O O   . ALA B 1 300 ? 137.790 129.710 166.852 1.00 93.92  ? 246 ALA B O   1 
ATOM   4764  C CB  . ALA B 1 300 ? 137.968 131.967 168.518 1.00 94.13  ? 246 ALA B CB  1 
ATOM   4765  N N   . SER B 1 301 ? 136.420 128.609 168.262 1.00 97.91  ? 247 SER B N   1 
ATOM   4766  C CA  . SER B 1 301 ? 136.246 127.479 167.355 1.00 87.69  ? 247 SER B CA  1 
ATOM   4767  C C   . SER B 1 301 ? 135.594 127.899 166.043 1.00 82.02  ? 247 SER B C   1 
ATOM   4768  O O   . SER B 1 301 ? 136.041 127.490 164.964 1.00 83.34  ? 247 SER B O   1 
ATOM   4769  C CB  . SER B 1 301 ? 135.421 126.391 168.038 1.00 89.12  ? 247 SER B CB  1 
ATOM   4770  O OG  . SER B 1 301 ? 134.200 126.916 168.530 1.00 91.71  ? 247 SER B OG  1 
ATOM   4771  N N   . ALA B 1 302 ? 134.540 128.716 166.113 1.00 78.09  ? 248 ALA B N   1 
ATOM   4772  C CA  . ALA B 1 302 ? 133.801 129.081 164.908 1.00 81.32  ? 248 ALA B CA  1 
ATOM   4773  C C   . ALA B 1 302 ? 134.686 129.828 163.921 1.00 79.43  ? 248 ALA B C   1 
ATOM   4774  O O   . ALA B 1 302 ? 134.609 129.600 162.708 1.00 75.62  ? 248 ALA B O   1 
ATOM   4775  C CB  . ALA B 1 302 ? 132.578 129.919 165.275 1.00 77.55  ? 248 ALA B CB  1 
ATOM   4776  N N   . ALA B 1 303 ? 135.542 130.718 164.428 1.00 77.71  ? 249 ALA B N   1 
ATOM   4777  C CA  . ALA B 1 303 ? 136.428 131.487 163.562 1.00 76.78  ? 249 ALA B CA  1 
ATOM   4778  C C   . ALA B 1 303 ? 137.349 130.573 162.763 1.00 77.78  ? 249 ALA B C   1 
ATOM   4779  O O   . ALA B 1 303 ? 137.445 130.684 161.534 1.00 76.74  ? 249 ALA B O   1 
ATOM   4780  C CB  . ALA B 1 303 ? 137.243 132.466 164.404 1.00 75.23  ? 249 ALA B CB  1 
ATOM   4781  N N   . ARG B 1 304 ? 138.031 129.657 163.451 1.00 69.03  ? 250 ARG B N   1 
ATOM   4782  C CA  . ARG B 1 304 ? 138.982 128.782 162.775 1.00 68.63  ? 250 ARG B CA  1 
ATOM   4783  C C   . ARG B 1 304 ? 138.274 127.816 161.835 1.00 71.76  ? 250 ARG B C   1 
ATOM   4784  O O   . ARG B 1 304 ? 138.774 127.529 160.739 1.00 73.42  ? 250 ARG B O   1 
ATOM   4785  C CB  . ARG B 1 304 ? 139.815 128.030 163.809 1.00 70.73  ? 250 ARG B CB  1 
ATOM   4786  C CG  . ARG B 1 304 ? 140.432 128.944 164.851 1.00 73.56  ? 250 ARG B CG  1 
ATOM   4787  C CD  . ARG B 1 304 ? 141.477 128.228 165.679 1.00 80.84  ? 250 ARG B CD  1 
ATOM   4788  N NE  . ARG B 1 304 ? 142.597 127.775 164.864 1.00 79.58  ? 250 ARG B NE  1 
ATOM   4789  C CZ  . ARG B 1 304 ? 143.725 127.282 165.353 1.00 77.35  ? 250 ARG B CZ  1 
ATOM   4790  N NH1 . ARG B 1 304 ? 143.923 127.171 166.656 1.00 79.37  ? 250 ARG B NH1 1 
ATOM   4791  N NH2 . ARG B 1 304 ? 144.681 126.893 164.514 1.00 76.22  ? 250 ARG B NH2 1 
ATOM   4792  N N   . VAL B 1 305 ? 137.107 127.310 162.241 1.00 70.37  ? 251 VAL B N   1 
ATOM   4793  C CA  . VAL B 1 305 ? 136.349 126.410 161.375 1.00 67.01  ? 251 VAL B CA  1 
ATOM   4794  C C   . VAL B 1 305 ? 135.962 127.120 160.084 1.00 68.73  ? 251 VAL B C   1 
ATOM   4795  O O   . VAL B 1 305 ? 136.145 126.588 158.979 1.00 67.12  ? 251 VAL B O   1 
ATOM   4796  C CB  . VAL B 1 305 ? 135.113 125.870 162.116 1.00 62.97  ? 251 VAL B CB  1 
ATOM   4797  C CG1 . VAL B 1 305 ? 134.144 125.232 161.138 1.00 61.18  ? 251 VAL B CG1 1 
ATOM   4798  C CG2 . VAL B 1 305 ? 135.531 124.870 163.179 1.00 65.54  ? 251 VAL B CG2 1 
ATOM   4799  N N   . ALA B 1 306 ? 135.430 128.340 160.204 1.00 70.71  ? 252 ALA B N   1 
ATOM   4800  C CA  . ALA B 1 306 ? 135.036 129.096 159.021 1.00 65.21  ? 252 ALA B CA  1 
ATOM   4801  C C   . ALA B 1 306 ? 136.237 129.384 158.132 1.00 60.71  ? 252 ALA B C   1 
ATOM   4802  O O   . ALA B 1 306 ? 136.168 129.223 156.908 1.00 61.65  ? 252 ALA B O   1 
ATOM   4803  C CB  . ALA B 1 306 ? 134.345 130.395 159.433 1.00 68.78  ? 252 ALA B CB  1 
ATOM   4804  N N   . LEU B 1 307 ? 137.355 129.803 158.733 1.00 61.64  ? 253 LEU B N   1 
ATOM   4805  C CA  . LEU B 1 307 ? 138.548 130.091 157.943 1.00 66.52  ? 253 LEU B CA  1 
ATOM   4806  C C   . LEU B 1 307 ? 138.996 128.865 157.158 1.00 64.19  ? 253 LEU B C   1 
ATOM   4807  O O   . LEU B 1 307 ? 139.223 128.940 155.944 1.00 66.98  ? 253 LEU B O   1 
ATOM   4808  C CB  . LEU B 1 307 ? 139.675 130.592 158.849 1.00 59.96  ? 253 LEU B CB  1 
ATOM   4809  C CG  . LEU B 1 307 ? 139.801 132.109 158.987 1.00 62.86  ? 253 LEU B CG  1 
ATOM   4810  C CD1 . LEU B 1 307 ? 140.878 132.479 159.989 1.00 62.02  ? 253 LEU B CD1 1 
ATOM   4811  C CD2 . LEU B 1 307 ? 140.095 132.732 157.636 1.00 62.96  ? 253 LEU B CD2 1 
ATOM   4812  N N   . GLY B 1 308 ? 139.113 127.720 157.834 1.00 57.25  ? 254 GLY B N   1 
ATOM   4813  C CA  . GLY B 1 308 ? 139.575 126.521 157.155 1.00 50.38  ? 254 GLY B CA  1 
ATOM   4814  C C   . GLY B 1 308 ? 138.648 126.092 156.034 1.00 53.12  ? 254 GLY B C   1 
ATOM   4815  O O   . GLY B 1 308 ? 139.092 125.813 154.914 1.00 53.84  ? 254 GLY B O   1 
ATOM   4816  N N   . ILE B 1 309 ? 137.342 126.049 156.316 1.00 55.47  ? 255 ILE B N   1 
ATOM   4817  C CA  . ILE B 1 309 ? 136.386 125.585 155.313 1.00 55.87  ? 255 ILE B CA  1 
ATOM   4818  C C   . ILE B 1 309 ? 136.388 126.516 154.106 1.00 60.18  ? 255 ILE B C   1 
ATOM   4819  O O   . ILE B 1 309 ? 136.439 126.069 152.951 1.00 59.45  ? 255 ILE B O   1 
ATOM   4820  C CB  . ILE B 1 309 ? 134.981 125.458 155.929 1.00 44.85  ? 255 ILE B CB  1 
ATOM   4821  C CG1 . ILE B 1 309 ? 134.971 124.377 157.011 1.00 44.59  ? 255 ILE B CG1 1 
ATOM   4822  C CG2 . ILE B 1 309 ? 133.955 125.147 154.856 1.00 44.77  ? 255 ILE B CG2 1 
ATOM   4823  C CD1 . ILE B 1 309 ? 133.609 124.128 157.615 1.00 51.62  ? 255 ILE B CD1 1 
ATOM   4824  N N   . THR B 1 310 ? 136.346 127.829 154.356 1.00 55.26  ? 256 THR B N   1 
ATOM   4825  C CA  . THR B 1 310 ? 136.310 128.788 153.259 1.00 49.07  ? 256 THR B CA  1 
ATOM   4826  C C   . THR B 1 310 ? 137.579 128.727 152.425 1.00 52.58  ? 256 THR B C   1 
ATOM   4827  O O   . THR B 1 310 ? 137.518 128.783 151.192 1.00 56.07  ? 256 THR B O   1 
ATOM   4828  C CB  . THR B 1 310 ? 136.096 130.199 153.803 1.00 50.43  ? 256 THR B CB  1 
ATOM   4829  O OG1 . THR B 1 310 ? 137.033 130.450 154.858 1.00 57.73  ? 256 THR B OG1 1 
ATOM   4830  C CG2 . THR B 1 310 ? 134.680 130.354 154.334 1.00 51.09  ? 256 THR B CG2 1 
ATOM   4831  N N   . THR B 1 311 ? 138.743 128.610 153.072 1.00 51.61  ? 257 THR B N   1 
ATOM   4832  C CA  . THR B 1 311 ? 139.989 128.550 152.316 1.00 55.79  ? 257 THR B CA  1 
ATOM   4833  C C   . THR B 1 311 ? 140.059 127.293 151.457 1.00 62.36  ? 257 THR B C   1 
ATOM   4834  O O   . THR B 1 311 ? 140.462 127.354 150.287 1.00 60.05  ? 257 THR B O   1 
ATOM   4835  C CB  . THR B 1 311 ? 141.186 128.622 153.262 1.00 51.49  ? 257 THR B CB  1 
ATOM   4836  O OG1 . THR B 1 311 ? 140.991 127.715 154.354 1.00 56.74  ? 257 THR B OG1 1 
ATOM   4837  C CG2 . THR B 1 311 ? 141.346 130.033 153.794 1.00 53.25  ? 257 THR B CG2 1 
ATOM   4838  N N   . VAL B 1 312 ? 139.658 126.145 152.012 1.00 60.77  ? 258 VAL B N   1 
ATOM   4839  C CA  . VAL B 1 312 ? 139.690 124.909 151.234 1.00 52.22  ? 258 VAL B CA  1 
ATOM   4840  C C   . VAL B 1 312 ? 138.758 125.014 150.032 1.00 56.20  ? 258 VAL B C   1 
ATOM   4841  O O   . VAL B 1 312 ? 139.127 124.662 148.903 1.00 62.46  ? 258 VAL B O   1 
ATOM   4842  C CB  . VAL B 1 312 ? 139.337 123.703 152.121 1.00 48.33  ? 258 VAL B CB  1 
ATOM   4843  C CG1 . VAL B 1 312 ? 139.168 122.458 151.272 1.00 56.01  ? 258 VAL B CG1 1 
ATOM   4844  C CG2 . VAL B 1 312 ? 140.418 123.484 153.163 1.00 52.08  ? 258 VAL B CG2 1 
ATOM   4845  N N   . LEU B 1 313 ? 137.539 125.514 150.253 1.00 52.56  ? 259 LEU B N   1 
ATOM   4846  C CA  . LEU B 1 313 ? 136.586 125.613 149.152 1.00 58.51  ? 259 LEU B CA  1 
ATOM   4847  C C   . LEU B 1 313 ? 137.055 126.601 148.089 1.00 62.06  ? 259 LEU B C   1 
ATOM   4848  O O   . LEU B 1 313 ? 136.885 126.356 146.889 1.00 64.71  ? 259 LEU B O   1 
ATOM   4849  C CB  . LEU B 1 313 ? 135.206 125.998 149.681 1.00 60.28  ? 259 LEU B CB  1 
ATOM   4850  C CG  . LEU B 1 313 ? 134.564 124.949 150.588 1.00 53.45  ? 259 LEU B CG  1 
ATOM   4851  C CD1 . LEU B 1 313 ? 133.099 125.263 150.830 1.00 56.03  ? 259 LEU B CD1 1 
ATOM   4852  C CD2 . LEU B 1 313 ? 134.729 123.558 149.999 1.00 54.39  ? 259 LEU B CD2 1 
ATOM   4853  N N   . THR B 1 314 ? 137.646 127.724 148.505 1.00 53.73  ? 260 THR B N   1 
ATOM   4854  C CA  . THR B 1 314 ? 138.146 128.693 147.535 1.00 54.21  ? 260 THR B CA  1 
ATOM   4855  C C   . THR B 1 314 ? 139.284 128.109 146.707 1.00 61.82  ? 260 THR B C   1 
ATOM   4856  O O   . THR B 1 314 ? 139.360 128.337 145.492 1.00 65.62  ? 260 THR B O   1 
ATOM   4857  C CB  . THR B 1 314 ? 138.601 129.962 148.250 1.00 51.03  ? 260 THR B CB  1 
ATOM   4858  O OG1 . THR B 1 314 ? 137.546 130.433 149.096 1.00 55.04  ? 260 THR B OG1 1 
ATOM   4859  C CG2 . THR B 1 314 ? 138.943 131.039 147.239 1.00 60.03  ? 260 THR B CG2 1 
ATOM   4860  N N   . MET B 1 315 ? 140.184 127.358 147.348 1.00 59.84  ? 261 MET B N   1 
ATOM   4861  C CA  . MET B 1 315 ? 141.253 126.710 146.596 1.00 58.09  ? 261 MET B CA  1 
ATOM   4862  C C   . MET B 1 315 ? 140.686 125.706 145.598 1.00 60.11  ? 261 MET B C   1 
ATOM   4863  O O   . MET B 1 315 ? 141.164 125.608 144.459 1.00 63.26  ? 261 MET B O   1 
ATOM   4864  C CB  . MET B 1 315 ? 142.231 126.033 147.554 1.00 57.81  ? 261 MET B CB  1 
ATOM   4865  C CG  . MET B 1 315 ? 143.531 125.601 146.903 1.00 59.44  ? 261 MET B CG  1 
ATOM   4866  S SD  . MET B 1 315 ? 144.456 126.994 146.230 1.00 66.60  ? 261 MET B SD  1 
ATOM   4867  C CE  . MET B 1 315 ? 144.751 127.943 147.717 1.00 53.19  ? 261 MET B CE  1 
ATOM   4868  N N   . THR B 1 316 ? 139.651 124.962 146.003 1.00 59.16  ? 262 THR B N   1 
ATOM   4869  C CA  . THR B 1 316 ? 139.002 124.051 145.065 1.00 61.27  ? 262 THR B CA  1 
ATOM   4870  C C   . THR B 1 316 ? 138.405 124.807 143.885 1.00 69.21  ? 262 THR B C   1 
ATOM   4871  O O   . THR B 1 316 ? 138.501 124.354 142.740 1.00 73.25  ? 262 THR B O   1 
ATOM   4872  C CB  . THR B 1 316 ? 137.916 123.233 145.762 1.00 59.79  ? 262 THR B CB  1 
ATOM   4873  O OG1 . THR B 1 316 ? 136.947 124.114 146.339 1.00 66.14  ? 262 THR B OG1 1 
ATOM   4874  C CG2 . THR B 1 316 ? 138.514 122.356 146.841 1.00 59.71  ? 262 THR B CG2 1 
ATOM   4875  N N   . THR B 1 317 ? 137.771 125.954 144.146 1.00 66.27  ? 263 THR B N   1 
ATOM   4876  C CA  . THR B 1 317 ? 137.184 126.735 143.056 1.00 66.63  ? 263 THR B CA  1 
ATOM   4877  C C   . THR B 1 317 ? 138.253 127.226 142.088 1.00 67.30  ? 263 THR B C   1 
ATOM   4878  O O   . THR B 1 317 ? 138.061 127.188 140.865 1.00 76.14  ? 263 THR B O   1 
ATOM   4879  C CB  . THR B 1 317 ? 136.394 127.922 143.605 1.00 63.93  ? 263 THR B CB  1 
ATOM   4880  O OG1 . THR B 1 317 ? 137.245 128.723 144.434 1.00 63.97  ? 263 THR B OG1 1 
ATOM   4881  C CG2 . THR B 1 317 ? 135.192 127.448 144.406 1.00 65.01  ? 263 THR B CG2 1 
ATOM   4882  N N   . ILE B 1 318 ? 139.383 127.699 142.619 1.00 62.21  ? 264 ILE B N   1 
ATOM   4883  C CA  . ILE B 1 318 ? 140.477 128.145 141.759 1.00 62.33  ? 264 ILE B CA  1 
ATOM   4884  C C   . ILE B 1 318 ? 140.967 126.996 140.889 1.00 71.10  ? 264 ILE B C   1 
ATOM   4885  O O   . ILE B 1 318 ? 141.169 127.152 139.674 1.00 77.03  ? 264 ILE B O   1 
ATOM   4886  C CB  . ILE B 1 318 ? 141.621 128.735 142.605 1.00 52.71  ? 264 ILE B CB  1 
ATOM   4887  C CG1 . ILE B 1 318 ? 141.180 130.029 143.288 1.00 54.24  ? 264 ILE B CG1 1 
ATOM   4888  C CG2 . ILE B 1 318 ? 142.850 128.974 141.746 1.00 49.40  ? 264 ILE B CG2 1 
ATOM   4889  C CD1 . ILE B 1 318 ? 142.268 130.670 144.119 1.00 49.83  ? 264 ILE B CD1 1 
ATOM   4890  N N   . ASN B 1 319 ? 141.160 125.820 141.495 1.00 69.97  ? 265 ASN B N   1 
ATOM   4891  C CA  . ASN B 1 319 ? 141.621 124.666 140.729 1.00 72.40  ? 265 ASN B CA  1 
ATOM   4892  C C   . ASN B 1 319 ? 140.619 124.280 139.649 1.00 77.08  ? 265 ASN B C   1 
ATOM   4893  O O   . ASN B 1 319 ? 141.008 123.952 138.521 1.00 78.78  ? 265 ASN B O   1 
ATOM   4894  C CB  . ASN B 1 319 ? 141.881 123.484 141.662 1.00 77.04  ? 265 ASN B CB  1 
ATOM   4895  C CG  . ASN B 1 319 ? 141.948 122.165 140.918 1.00 88.57  ? 265 ASN B CG  1 
ATOM   4896  O OD1 . ASN B 1 319 ? 142.939 121.861 140.255 1.00 93.59  ? 265 ASN B OD1 1 
ATOM   4897  N ND2 . ASN B 1 319 ? 140.890 121.371 141.028 1.00 89.11  ? 265 ASN B ND2 1 
ATOM   4898  N N   . THR B 1 320 ? 139.325 124.305 139.978 1.00 78.02  ? 266 THR B N   1 
ATOM   4899  C CA  . THR B 1 320 ? 138.306 123.941 138.998 1.00 81.16  ? 266 THR B CA  1 
ATOM   4900  C C   . THR B 1 320 ? 138.295 124.911 137.827 1.00 81.91  ? 266 THR B C   1 
ATOM   4901  O O   . THR B 1 320 ? 138.205 124.489 136.669 1.00 87.48  ? 266 THR B O   1 
ATOM   4902  C CB  . THR B 1 320 ? 136.925 123.888 139.653 1.00 80.55  ? 266 THR B CB  1 
ATOM   4903  O OG1 . THR B 1 320 ? 136.683 125.109 140.360 1.00 83.91  ? 266 THR B OG1 1 
ATOM   4904  C CG2 . THR B 1 320 ? 136.829 122.716 140.612 1.00 78.18  ? 266 THR B CG2 1 
ATOM   4905  N N   . HIS B 1 321 ? 138.390 126.213 138.104 1.00 78.05  ? 267 HIS B N   1 
ATOM   4906  C CA  . HIS B 1 321 ? 138.449 127.187 137.019 1.00 79.47  ? 267 HIS B CA  1 
ATOM   4907  C C   . HIS B 1 321 ? 139.660 126.935 136.129 1.00 81.20  ? 267 HIS B C   1 
ATOM   4908  O O   . HIS B 1 321 ? 139.549 126.900 134.894 1.00 86.55  ? 267 HIS B O   1 
ATOM   4909  C CB  . HIS B 1 321 ? 138.480 128.608 137.586 1.00 83.00  ? 267 HIS B CB  1 
ATOM   4910  C CG  . HIS B 1 321 ? 137.161 129.076 138.117 1.00 97.37  ? 267 HIS B CG  1 
ATOM   4911  N ND1 . HIS B 1 321 ? 136.785 130.402 138.107 1.00 100.39 ? 267 HIS B ND1 1 
ATOM   4912  C CD2 . HIS B 1 321 ? 136.131 128.396 138.674 1.00 98.36  ? 267 HIS B CD2 1 
ATOM   4913  C CE1 . HIS B 1 321 ? 135.580 130.519 138.635 1.00 104.61 ? 267 HIS B CE1 1 
ATOM   4914  N NE2 . HIS B 1 321 ? 135.160 129.317 138.987 1.00 101.76 ? 267 HIS B NE2 1 
ATOM   4915  N N   . LEU B 1 322 ? 140.827 126.724 136.746 1.00 80.73  ? 268 LEU B N   1 
ATOM   4916  C CA  . LEU B 1 322 ? 142.037 126.509 135.960 1.00 84.83  ? 268 LEU B CA  1 
ATOM   4917  C C   . LEU B 1 322 ? 141.915 125.275 135.076 1.00 84.47  ? 268 LEU B C   1 
ATOM   4918  O O   . LEU B 1 322 ? 142.262 125.317 133.890 1.00 80.35  ? 268 LEU B O   1 
ATOM   4919  C CB  . LEU B 1 322 ? 143.252 126.382 136.875 1.00 83.42  ? 268 LEU B CB  1 
ATOM   4920  C CG  . LEU B 1 322 ? 144.511 125.934 136.129 1.00 79.15  ? 268 LEU B CG  1 
ATOM   4921  C CD1 . LEU B 1 322 ? 145.039 127.048 135.238 1.00 73.81  ? 268 LEU B CD1 1 
ATOM   4922  C CD2 . LEU B 1 322 ? 145.574 125.458 137.092 1.00 69.56  ? 268 LEU B CD2 1 
ATOM   4923  N N   . ARG B 1 323 ? 141.417 124.167 135.628 1.00 83.70  ? 269 ARG B N   1 
ATOM   4924  C CA  . ARG B 1 323 ? 141.339 122.946 134.836 1.00 85.46  ? 269 ARG B CA  1 
ATOM   4925  C C   . ARG B 1 323 ? 140.177 122.970 133.853 1.00 82.60  ? 269 ARG B C   1 
ATOM   4926  O O   . ARG B 1 323 ? 140.135 122.146 132.934 1.00 81.55  ? 269 ARG B O   1 
ATOM   4927  C CB  . ARG B 1 323 ? 141.239 121.720 135.746 1.00 88.01  ? 269 ARG B CB  1 
ATOM   4928  C CG  . ARG B 1 323 ? 139.993 121.657 136.607 1.00 89.81  ? 269 ARG B CG  1 
ATOM   4929  C CD  . ARG B 1 323 ? 140.049 120.439 137.511 1.00 87.43  ? 269 ARG B CD  1 
ATOM   4930  N NE  . ARG B 1 323 ? 138.982 120.419 138.503 1.00 90.68  ? 269 ARG B NE  1 
ATOM   4931  C CZ  . ARG B 1 323 ? 138.877 119.511 139.463 1.00 94.45  ? 269 ARG B CZ  1 
ATOM   4932  N NH1 . ARG B 1 323 ? 139.756 118.530 139.585 1.00 100.02 ? 269 ARG B NH1 1 
ATOM   4933  N NH2 . ARG B 1 323 ? 137.869 119.593 140.327 1.00 92.99  ? 269 ARG B NH2 1 
ATOM   4934  N N   . GLU B 1 324 ? 139.230 123.897 134.021 1.00 87.01  ? 270 GLU B N   1 
ATOM   4935  C CA  . GLU B 1 324 ? 138.180 124.044 133.020 1.00 91.59  ? 270 GLU B CA  1 
ATOM   4936  C C   . GLU B 1 324 ? 138.553 125.076 131.966 1.00 85.13  ? 270 GLU B C   1 
ATOM   4937  O O   . GLU B 1 324 ? 137.808 125.270 130.998 1.00 81.54  ? 270 GLU B O   1 
ATOM   4938  C CB  . GLU B 1 324 ? 136.859 124.419 133.691 1.00 95.41  ? 270 GLU B CB  1 
ATOM   4939  C CG  . GLU B 1 324 ? 136.204 123.270 134.437 1.00 99.79  ? 270 GLU B CG  1 
ATOM   4940  C CD  . GLU B 1 324 ? 134.899 123.670 135.092 1.00 115.29 ? 270 GLU B CD  1 
ATOM   4941  O OE1 . GLU B 1 324 ? 134.666 124.885 135.263 1.00 115.32 ? 270 GLU B OE1 1 
ATOM   4942  O OE2 . GLU B 1 324 ? 134.104 122.769 135.432 1.00 124.21 ? 270 GLU B OE2 1 
ATOM   4943  N N   . THR B 1 325 ? 139.693 125.748 132.131 1.00 85.61  ? 271 THR B N   1 
ATOM   4944  C CA  . THR B 1 325 ? 140.194 126.658 131.109 1.00 87.91  ? 271 THR B CA  1 
ATOM   4945  C C   . THR B 1 325 ? 141.192 126.002 130.150 1.00 89.67  ? 271 THR B C   1 
ATOM   4946  O O   . THR B 1 325 ? 141.749 126.693 129.290 1.00 85.14  ? 271 THR B O   1 
ATOM   4947  C CB  . THR B 1 325 ? 140.837 127.884 131.759 1.00 86.64  ? 271 THR B CB  1 
ATOM   4948  O OG1 . THR B 1 325 ? 141.735 127.463 132.794 1.00 82.05  ? 271 THR B OG1 1 
ATOM   4949  C CG2 . THR B 1 325 ? 139.774 128.799 132.346 1.00 86.44  ? 271 THR B CG2 1 
ATOM   4950  N N   . LEU B 1 326 ? 141.428 124.698 130.268 1.00 91.40  ? 272 LEU B N   1 
ATOM   4951  C CA  . LEU B 1 326 ? 142.470 124.038 129.493 1.00 84.82  ? 272 LEU B CA  1 
ATOM   4952  C C   . LEU B 1 326 ? 141.946 122.706 128.978 1.00 81.98  ? 272 LEU B C   1 
ATOM   4953  O O   . LEU B 1 326 ? 140.977 122.163 129.522 1.00 87.88  ? 272 LEU B O   1 
ATOM   4954  C CB  . LEU B 1 326 ? 143.736 123.826 130.334 1.00 82.25  ? 272 LEU B CB  1 
ATOM   4955  C CG  . LEU B 1 326 ? 144.654 125.040 130.454 1.00 79.89  ? 272 LEU B CG  1 
ATOM   4956  C CD1 . LEU B 1 326 ? 145.751 124.778 131.465 1.00 75.55  ? 272 LEU B CD1 1 
ATOM   4957  C CD2 . LEU B 1 326 ? 145.247 125.381 129.098 1.00 70.97  ? 272 LEU B CD2 1 
ATOM   4958  N N   . PRO B 1 327 ? 142.561 122.156 127.931 1.00 78.84  ? 273 PRO B N   1 
ATOM   4959  C CA  . PRO B 1 327 ? 142.164 120.827 127.449 1.00 79.68  ? 273 PRO B CA  1 
ATOM   4960  C C   . PRO B 1 327 ? 142.673 119.722 128.364 1.00 80.36  ? 273 PRO B C   1 
ATOM   4961  O O   . PRO B 1 327 ? 143.316 119.958 129.388 1.00 86.78  ? 273 PRO B O   1 
ATOM   4962  C CB  . PRO B 1 327 ? 142.811 120.746 126.063 1.00 79.09  ? 273 PRO B CB  1 
ATOM   4963  C CG  . PRO B 1 327 ? 143.980 121.660 126.151 1.00 78.59  ? 273 PRO B CG  1 
ATOM   4964  C CD  . PRO B 1 327 ? 143.541 122.793 127.034 1.00 80.83  ? 273 PRO B CD  1 
ATOM   4965  N N   . LYS B 1 328 ? 142.372 118.486 127.968 1.00 77.19  ? 274 LYS B N   1 
ATOM   4966  C CA  . LYS B 1 328 ? 142.681 117.308 128.781 1.00 73.79  ? 274 LYS B CA  1 
ATOM   4967  C C   . LYS B 1 328 ? 143.969 116.630 128.307 1.00 75.65  ? 274 LYS B C   1 
ATOM   4968  O O   . LYS B 1 328 ? 143.959 115.599 127.635 1.00 83.33  ? 274 LYS B O   1 
ATOM   4969  C CB  . LYS B 1 328 ? 141.508 116.335 128.758 1.00 69.98  ? 274 LYS B CB  1 
ATOM   4970  C CG  . LYS B 1 328 ? 140.196 116.933 129.230 1.00 71.31  ? 274 LYS B CG  1 
ATOM   4971  C CD  . LYS B 1 328 ? 139.066 115.924 129.140 1.00 71.07  ? 274 LYS B CD  1 
ATOM   4972  C CE  . LYS B 1 328 ? 137.743 116.543 129.551 1.00 73.69  ? 274 LYS B CE  1 
ATOM   4973  N NZ  . LYS B 1 328 ? 136.624 115.565 129.461 1.00 80.56  ? 274 LYS B NZ  1 
ATOM   4974  N N   . ILE B 1 329 ? 145.096 117.232 128.672 1.00 72.20  ? 275 ILE B N   1 
ATOM   4975  C CA  . ILE B 1 329 ? 146.404 116.626 128.430 1.00 73.62  ? 275 ILE B CA  1 
ATOM   4976  C C   . ILE B 1 329 ? 146.654 115.576 129.508 1.00 79.48  ? 275 ILE B C   1 
ATOM   4977  O O   . ILE B 1 329 ? 146.207 115.748 130.651 1.00 86.56  ? 275 ILE B O   1 
ATOM   4978  C CB  . ILE B 1 329 ? 147.523 117.681 128.402 1.00 75.49  ? 275 ILE B CB  1 
ATOM   4979  C CG1 . ILE B 1 329 ? 147.501 118.542 129.671 1.00 76.94  ? 275 ILE B CG1 1 
ATOM   4980  C CG2 . ILE B 1 329 ? 147.416 118.539 127.147 1.00 74.37  ? 275 ILE B CG2 1 
ATOM   4981  C CD1 . ILE B 1 329 ? 146.686 119.818 129.551 1.00 76.23  ? 275 ILE B CD1 1 
ATOM   4982  N N   . PRO B 1 330 ? 147.352 114.484 129.202 1.00 79.86  ? 276 PRO B N   1 
ATOM   4983  C CA  . PRO B 1 330 ? 147.561 113.416 130.191 1.00 80.48  ? 276 PRO B CA  1 
ATOM   4984  C C   . PRO B 1 330 ? 148.693 113.654 131.182 1.00 84.88  ? 276 PRO B C   1 
ATOM   4985  O O   . PRO B 1 330 ? 148.816 112.879 132.134 1.00 87.23  ? 276 PRO B O   1 
ATOM   4986  C CB  . PRO B 1 330 ? 147.885 112.211 129.299 1.00 84.76  ? 276 PRO B CB  1 
ATOM   4987  C CG  . PRO B 1 330 ? 148.584 112.807 128.137 1.00 85.68  ? 276 PRO B CG  1 
ATOM   4988  C CD  . PRO B 1 330 ? 147.905 114.128 127.883 1.00 82.28  ? 276 PRO B CD  1 
ATOM   4989  N N   . TYR B 1 331 ? 149.514 114.679 130.994 1.00 85.85  ? 277 TYR B N   1 
ATOM   4990  C CA  . TYR B 1 331 ? 150.655 114.942 131.859 1.00 84.54  ? 277 TYR B CA  1 
ATOM   4991  C C   . TYR B 1 331 ? 150.318 116.049 132.853 1.00 82.55  ? 277 TYR B C   1 
ATOM   4992  O O   . TYR B 1 331 ? 149.188 116.540 132.922 1.00 86.23  ? 277 TYR B O   1 
ATOM   4993  C CB  . TYR B 1 331 ? 151.887 115.300 131.027 1.00 82.68  ? 277 TYR B CB  1 
ATOM   4994  C CG  . TYR B 1 331 ? 151.591 116.189 129.844 1.00 78.05  ? 277 TYR B CG  1 
ATOM   4995  C CD1 . TYR B 1 331 ? 151.402 117.553 130.005 1.00 72.27  ? 277 TYR B CD1 1 
ATOM   4996  C CD2 . TYR B 1 331 ? 151.508 115.663 128.564 1.00 79.18  ? 277 TYR B CD2 1 
ATOM   4997  C CE1 . TYR B 1 331 ? 151.136 118.366 128.924 1.00 75.91  ? 277 TYR B CE1 1 
ATOM   4998  C CE2 . TYR B 1 331 ? 151.243 116.468 127.478 1.00 79.27  ? 277 TYR B CE2 1 
ATOM   4999  C CZ  . TYR B 1 331 ? 151.057 117.818 127.663 1.00 79.47  ? 277 TYR B CZ  1 
ATOM   5000  O OH  . TYR B 1 331 ? 150.792 118.625 126.582 1.00 77.92  ? 277 TYR B OH  1 
ATOM   5001  N N   . VAL B 1 332 ? 151.324 116.442 133.631 1.00 76.45  ? 278 VAL B N   1 
ATOM   5002  C CA  . VAL B 1 332 ? 151.164 117.422 134.698 1.00 71.17  ? 278 VAL B CA  1 
ATOM   5003  C C   . VAL B 1 332 ? 151.715 118.758 134.226 1.00 73.99  ? 278 VAL B C   1 
ATOM   5004  O O   . VAL B 1 332 ? 152.861 118.840 133.767 1.00 78.52  ? 278 VAL B O   1 
ATOM   5005  C CB  . VAL B 1 332 ? 151.873 116.968 135.984 1.00 67.90  ? 278 VAL B CB  1 
ATOM   5006  C CG1 . VAL B 1 332 ? 151.270 117.665 137.191 1.00 69.55  ? 278 VAL B CG1 1 
ATOM   5007  C CG2 . VAL B 1 332 ? 151.802 115.460 136.130 1.00 71.79  ? 278 VAL B CG2 1 
ATOM   5008  N N   . LYS B 1 333 ? 150.905 119.803 134.338 0.50 66.49  ? 279 LYS B N   1 
ATOM   5009  C CA  . LYS B 1 333 ? 151.339 121.154 134.026 0.50 62.46  ? 279 LYS B CA  1 
ATOM   5010  C C   . LYS B 1 333 ? 151.930 121.818 135.266 0.50 63.33  ? 279 LYS B C   1 
ATOM   5011  O O   . LYS B 1 333 ? 151.658 121.425 136.401 0.50 66.40  ? 279 LYS B O   1 
ATOM   5012  C CB  . LYS B 1 333 ? 150.172 121.977 133.486 1.00 63.65  ? 279 LYS B CB  1 
ATOM   5013  C CG  . LYS B 1 333 ? 149.584 121.424 132.204 1.00 65.61  ? 279 LYS B CG  1 
ATOM   5014  C CD  . LYS B 1 333 ? 148.278 122.104 131.861 1.00 64.36  ? 279 LYS B CD  1 
ATOM   5015  C CE  . LYS B 1 333 ? 147.200 121.729 132.857 1.00 67.41  ? 279 LYS B CE  1 
ATOM   5016  N NZ  . LYS B 1 333 ? 147.004 120.255 132.923 1.00 70.69  ? 279 LYS B NZ  1 
ATOM   5017  N N   . ALA B 1 334 ? 152.762 122.835 135.029 1.00 58.87  ? 280 ALA B N   1 
ATOM   5018  C CA  . ALA B 1 334 ? 153.408 123.534 136.136 1.00 60.09  ? 280 ALA B CA  1 
ATOM   5019  C C   . ALA B 1 334 ? 152.389 124.251 137.013 1.00 62.88  ? 280 ALA B C   1 
ATOM   5020  O O   . ALA B 1 334 ? 152.496 124.235 138.246 1.00 64.93  ? 280 ALA B O   1 
ATOM   5021  C CB  . ALA B 1 334 ? 154.442 124.521 135.602 1.00 59.76  ? 280 ALA B CB  1 
ATOM   5022  N N   . ILE B 1 335 ? 151.396 124.892 136.395 1.00 60.07  ? 281 ILE B N   1 
ATOM   5023  C CA  . ILE B 1 335 ? 150.390 125.605 137.171 1.00 58.62  ? 281 ILE B CA  1 
ATOM   5024  C C   . ILE B 1 335 ? 149.555 124.624 137.986 1.00 63.48  ? 281 ILE B C   1 
ATOM   5025  O O   . ILE B 1 335 ? 149.147 124.924 139.115 1.00 70.18  ? 281 ILE B O   1 
ATOM   5026  C CB  . ILE B 1 335 ? 149.527 126.486 136.247 1.00 58.48  ? 281 ILE B CB  1 
ATOM   5027  C CG1 . ILE B 1 335 ? 148.545 127.328 137.063 1.00 64.06  ? 281 ILE B CG1 1 
ATOM   5028  C CG2 . ILE B 1 335 ? 148.803 125.644 135.210 1.00 60.63  ? 281 ILE B CG2 1 
ATOM   5029  C CD1 . ILE B 1 335 ? 149.203 128.202 138.102 1.00 62.01  ? 281 ILE B CD1 1 
ATOM   5030  N N   . ASP B 1 336 ? 149.300 123.432 137.439 1.00 62.44  ? 282 ASP B N   1 
ATOM   5031  C CA  . ASP B 1 336 ? 148.620 122.397 138.211 1.00 65.84  ? 282 ASP B CA  1 
ATOM   5032  C C   . ASP B 1 336 ? 149.450 121.975 139.415 1.00 67.00  ? 282 ASP B C   1 
ATOM   5033  O O   . ASP B 1 336 ? 148.909 121.754 140.503 1.00 66.28  ? 282 ASP B O   1 
ATOM   5034  C CB  . ASP B 1 336 ? 148.315 121.190 137.326 1.00 75.71  ? 282 ASP B CB  1 
ATOM   5035  C CG  . ASP B 1 336 ? 147.143 121.429 136.401 1.00 87.50  ? 282 ASP B CG  1 
ATOM   5036  O OD1 . ASP B 1 336 ? 146.671 122.581 136.326 1.00 86.28  ? 282 ASP B OD1 1 
ATOM   5037  O OD2 . ASP B 1 336 ? 146.688 120.462 135.756 1.00 97.92  ? 282 ASP B OD2 1 
ATOM   5038  N N   . MET B 1 337 ? 150.768 121.856 139.238 1.00 65.06  ? 283 MET B N   1 
ATOM   5039  C CA  . MET B 1 337 ? 151.642 121.532 140.361 1.00 64.54  ? 283 MET B CA  1 
ATOM   5040  C C   . MET B 1 337 ? 151.573 122.608 141.437 1.00 64.67  ? 283 MET B C   1 
ATOM   5041  O O   . MET B 1 337 ? 151.481 122.304 142.633 1.00 68.61  ? 283 MET B O   1 
ATOM   5042  C CB  . MET B 1 337 ? 153.079 121.360 139.872 1.00 61.73  ? 283 MET B CB  1 
ATOM   5043  C CG  . MET B 1 337 ? 153.328 120.074 139.111 1.00 71.32  ? 283 MET B CG  1 
ATOM   5044  S SD  . MET B 1 337 ? 153.171 118.635 140.179 1.00 114.54 ? 283 MET B SD  1 
ATOM   5045  C CE  . MET B 1 337 ? 154.344 119.056 141.463 1.00 89.07  ? 283 MET B CE  1 
ATOM   5046  N N   . TYR B 1 338 ? 151.622 123.877 141.030 1.00 58.82  ? 284 TYR B N   1 
ATOM   5047  C CA  . TYR B 1 338 ? 151.570 124.959 142.008 1.00 53.73  ? 284 TYR B CA  1 
ATOM   5048  C C   . TYR B 1 338 ? 150.235 124.975 142.742 1.00 57.50  ? 284 TYR B C   1 
ATOM   5049  O O   . TYR B 1 338 ? 150.188 125.188 143.960 1.00 66.99  ? 284 TYR B O   1 
ATOM   5050  C CB  . TYR B 1 338 ? 151.825 126.302 141.326 1.00 51.63  ? 284 TYR B CB  1 
ATOM   5051  C CG  . TYR B 1 338 ? 152.079 127.437 142.291 1.00 51.36  ? 284 TYR B CG  1 
ATOM   5052  C CD1 . TYR B 1 338 ? 153.348 127.670 142.797 1.00 50.24  ? 284 TYR B CD1 1 
ATOM   5053  C CD2 . TYR B 1 338 ? 151.051 128.277 142.693 1.00 47.28  ? 284 TYR B CD2 1 
ATOM   5054  C CE1 . TYR B 1 338 ? 153.587 128.704 143.675 1.00 47.27  ? 284 TYR B CE1 1 
ATOM   5055  C CE2 . TYR B 1 338 ? 151.282 129.315 143.571 1.00 42.16  ? 284 TYR B CE2 1 
ATOM   5056  C CZ  . TYR B 1 338 ? 152.552 129.523 144.058 1.00 47.17  ? 284 TYR B CZ  1 
ATOM   5057  O OH  . TYR B 1 338 ? 152.790 130.555 144.934 1.00 58.43  ? 284 TYR B OH  1 
ATOM   5058  N N   . LEU B 1 339 ? 149.135 124.755 142.017 1.00 54.40  ? 285 LEU B N   1 
ATOM   5059  C CA  . LEU B 1 339 ? 147.827 124.725 142.664 1.00 56.38  ? 285 LEU B CA  1 
ATOM   5060  C C   . LEU B 1 339 ? 147.707 123.542 143.614 1.00 59.36  ? 285 LEU B C   1 
ATOM   5061  O O   . LEU B 1 339 ? 147.104 123.662 144.684 1.00 63.01  ? 285 LEU B O   1 
ATOM   5062  C CB  . LEU B 1 339 ? 146.712 124.691 141.622 1.00 55.93  ? 285 LEU B CB  1 
ATOM   5063  C CG  . LEU B 1 339 ? 146.464 125.963 140.808 1.00 55.27  ? 285 LEU B CG  1 
ATOM   5064  C CD1 . LEU B 1 339 ? 144.983 126.109 140.516 1.00 59.79  ? 285 LEU B CD1 1 
ATOM   5065  C CD2 . LEU B 1 339 ? 146.991 127.198 141.518 1.00 52.17  ? 285 LEU B CD2 1 
ATOM   5066  N N   . MET B 1 340 ? 148.269 122.389 143.242 1.00 61.23  ? 286 MET B N   1 
ATOM   5067  C CA  . MET B 1 340 ? 148.259 121.243 144.145 1.00 63.78  ? 286 MET B CA  1 
ATOM   5068  C C   . MET B 1 340 ? 149.070 121.526 145.401 1.00 61.60  ? 286 MET B C   1 
ATOM   5069  O O   . MET B 1 340 ? 148.670 121.138 146.503 1.00 61.60  ? 286 MET B O   1 
ATOM   5070  C CB  . MET B 1 340 ? 148.787 119.999 143.431 1.00 66.65  ? 286 MET B CB  1 
ATOM   5071  C CG  . MET B 1 340 ? 147.803 119.388 142.446 1.00 77.31  ? 286 MET B CG  1 
ATOM   5072  S SD  . MET B 1 340 ? 148.406 117.866 141.690 1.00 88.71  ? 286 MET B SD  1 
ATOM   5073  C CE  . MET B 1 340 ? 146.961 117.364 140.761 1.00 76.06  ? 286 MET B CE  1 
ATOM   5074  N N   . GLY B 1 341 ? 150.211 122.201 145.257 1.00 59.36  ? 287 GLY B N   1 
ATOM   5075  C CA  . GLY B 1 341 ? 150.985 122.577 146.431 1.00 57.72  ? 287 GLY B CA  1 
ATOM   5076  C C   . GLY B 1 341 ? 150.233 123.530 147.342 1.00 59.29  ? 287 GLY B C   1 
ATOM   5077  O O   . GLY B 1 341 ? 150.228 123.367 148.568 1.00 61.43  ? 287 GLY B O   1 
ATOM   5078  N N   . CYS B 1 342 ? 149.583 124.537 146.756 1.00 55.42  ? 288 CYS B N   1 
ATOM   5079  C CA  . CYS B 1 342 ? 148.788 125.464 147.556 1.00 53.62  ? 288 CYS B CA  1 
ATOM   5080  C C   . CYS B 1 342 ? 147.636 124.747 148.248 1.00 59.72  ? 288 CYS B C   1 
ATOM   5081  O O   . CYS B 1 342 ? 147.314 125.044 149.405 1.00 67.54  ? 288 CYS B O   1 
ATOM   5082  C CB  . CYS B 1 342 ? 148.268 126.605 146.684 1.00 53.13  ? 288 CYS B CB  1 
ATOM   5083  S SG  . CYS B 1 342 ? 149.532 127.794 146.199 1.00 63.93  ? 288 CYS B SG  1 
ATOM   5084  N N   . PHE B 1 343 ? 146.994 123.807 147.552 1.00 58.33  ? 289 PHE B N   1 
ATOM   5085  C CA  . PHE B 1 343 ? 145.931 123.022 148.167 1.00 54.04  ? 289 PHE B CA  1 
ATOM   5086  C C   . PHE B 1 343 ? 146.457 122.173 149.315 1.00 57.13  ? 289 PHE B C   1 
ATOM   5087  O O   . PHE B 1 343 ? 145.790 122.045 150.349 1.00 63.52  ? 289 PHE B O   1 
ATOM   5088  C CB  . PHE B 1 343 ? 145.258 122.142 147.117 1.00 58.11  ? 289 PHE B CB  1 
ATOM   5089  C CG  . PHE B 1 343 ? 144.017 121.461 147.605 1.00 62.85  ? 289 PHE B CG  1 
ATOM   5090  C CD1 . PHE B 1 343 ? 142.802 122.121 147.591 1.00 61.13  ? 289 PHE B CD1 1 
ATOM   5091  C CD2 . PHE B 1 343 ? 144.063 120.161 148.075 1.00 70.05  ? 289 PHE B CD2 1 
ATOM   5092  C CE1 . PHE B 1 343 ? 141.658 121.499 148.038 1.00 66.17  ? 289 PHE B CE1 1 
ATOM   5093  C CE2 . PHE B 1 343 ? 142.921 119.532 148.522 1.00 70.06  ? 289 PHE B CE2 1 
ATOM   5094  C CZ  . PHE B 1 343 ? 141.716 120.202 148.504 1.00 71.36  ? 289 PHE B CZ  1 
ATOM   5095  N N   . VAL B 1 344 ? 147.648 121.596 149.155 1.00 56.45  ? 290 VAL B N   1 
ATOM   5096  C CA  . VAL B 1 344 ? 148.256 120.827 150.236 1.00 57.49  ? 290 VAL B CA  1 
ATOM   5097  C C   . VAL B 1 344 ? 148.486 121.717 151.450 1.00 60.47  ? 290 VAL B C   1 
ATOM   5098  O O   . VAL B 1 344 ? 148.215 121.323 152.588 1.00 62.02  ? 290 VAL B O   1 
ATOM   5099  C CB  . VAL B 1 344 ? 149.562 120.167 149.759 1.00 55.30  ? 290 VAL B CB  1 
ATOM   5100  C CG1 . VAL B 1 344 ? 150.371 119.676 150.945 1.00 51.59  ? 290 VAL B CG1 1 
ATOM   5101  C CG2 . VAL B 1 344 ? 149.252 119.013 148.821 1.00 59.97  ? 290 VAL B CG2 1 
ATOM   5102  N N   . PHE B 1 345 ? 148.986 122.934 151.227 1.00 59.38  ? 291 PHE B N   1 
ATOM   5103  C CA  . PHE B 1 345 ? 149.214 123.842 152.352 1.00 55.10  ? 291 PHE B CA  1 
ATOM   5104  C C   . PHE B 1 345 ? 147.906 124.241 153.034 1.00 53.99  ? 291 PHE B C   1 
ATOM   5105  O O   . PHE B 1 345 ? 147.814 124.237 154.271 1.00 56.32  ? 291 PHE B O   1 
ATOM   5106  C CB  . PHE B 1 345 ? 149.978 125.080 151.888 1.00 50.65  ? 291 PHE B CB  1 
ATOM   5107  C CG  . PHE B 1 345 ? 151.467 124.894 151.855 1.00 52.79  ? 291 PHE B CG  1 
ATOM   5108  C CD1 . PHE B 1 345 ? 152.060 124.115 150.879 1.00 58.29  ? 291 PHE B CD1 1 
ATOM   5109  C CD2 . PHE B 1 345 ? 152.274 125.504 152.797 1.00 53.85  ? 291 PHE B CD2 1 
ATOM   5110  C CE1 . PHE B 1 345 ? 153.427 123.944 150.844 1.00 54.97  ? 291 PHE B CE1 1 
ATOM   5111  C CE2 . PHE B 1 345 ? 153.643 125.337 152.768 1.00 57.40  ? 291 PHE B CE2 1 
ATOM   5112  C CZ  . PHE B 1 345 ? 154.220 124.556 151.789 1.00 56.00  ? 291 PHE B CZ  1 
ATOM   5113  N N   . VAL B 1 346 ? 146.880 124.589 152.251 1.00 50.87  ? 292 VAL B N   1 
ATOM   5114  C CA  . VAL B 1 346 ? 145.627 125.035 152.850 1.00 48.69  ? 292 VAL B CA  1 
ATOM   5115  C C   . VAL B 1 346 ? 144.840 123.896 153.474 1.00 55.33  ? 292 VAL B C   1 
ATOM   5116  O O   . VAL B 1 346 ? 143.933 124.151 154.273 1.00 61.64  ? 292 VAL B O   1 
ATOM   5117  C CB  . VAL B 1 346 ? 144.729 125.770 151.835 1.00 49.35  ? 292 VAL B CB  1 
ATOM   5118  C CG1 . VAL B 1 346 ? 145.461 126.959 151.241 1.00 57.72  ? 292 VAL B CG1 1 
ATOM   5119  C CG2 . VAL B 1 346 ? 144.253 124.823 150.756 1.00 56.81  ? 292 VAL B CG2 1 
ATOM   5120  N N   . PHE B 1 347 ? 145.155 122.647 153.134 1.00 57.35  ? 293 PHE B N   1 
ATOM   5121  C CA  . PHE B 1 347 ? 144.613 121.516 153.873 1.00 56.72  ? 293 PHE B CA  1 
ATOM   5122  C C   . PHE B 1 347 ? 145.437 121.169 155.102 1.00 57.18  ? 293 PHE B C   1 
ATOM   5123  O O   . PHE B 1 347 ? 144.878 120.712 156.106 1.00 57.31  ? 293 PHE B O   1 
ATOM   5124  C CB  . PHE B 1 347 ? 144.513 120.282 152.971 1.00 60.04  ? 293 PHE B CB  1 
ATOM   5125  C CG  . PHE B 1 347 ? 143.176 119.610 153.024 1.00 65.75  ? 293 PHE B CG  1 
ATOM   5126  C CD1 . PHE B 1 347 ? 142.772 118.930 154.160 1.00 63.92  ? 293 PHE B CD1 1 
ATOM   5127  C CD2 . PHE B 1 347 ? 142.319 119.660 151.939 1.00 68.47  ? 293 PHE B CD2 1 
ATOM   5128  C CE1 . PHE B 1 347 ? 141.539 118.313 154.212 1.00 66.80  ? 293 PHE B CE1 1 
ATOM   5129  C CE2 . PHE B 1 347 ? 141.087 119.043 151.984 1.00 67.99  ? 293 PHE B CE2 1 
ATOM   5130  C CZ  . PHE B 1 347 ? 140.696 118.367 153.122 1.00 69.85  ? 293 PHE B CZ  1 
ATOM   5131  N N   . LEU B 1 348 ? 146.753 121.385 155.045 1.00 55.67  ? 294 LEU B N   1 
ATOM   5132  C CA  . LEU B 1 348 ? 147.588 121.197 156.223 1.00 57.43  ? 294 LEU B CA  1 
ATOM   5133  C C   . LEU B 1 348 ? 147.252 122.207 157.307 1.00 61.69  ? 294 LEU B C   1 
ATOM   5134  O O   . LEU B 1 348 ? 147.427 121.915 158.489 1.00 63.23  ? 294 LEU B O   1 
ATOM   5135  C CB  . LEU B 1 348 ? 149.067 121.296 155.852 1.00 57.78  ? 294 LEU B CB  1 
ATOM   5136  C CG  . LEU B 1 348 ? 149.700 120.070 155.197 1.00 59.17  ? 294 LEU B CG  1 
ATOM   5137  C CD1 . LEU B 1 348 ? 151.196 120.273 155.022 1.00 61.73  ? 294 LEU B CD1 1 
ATOM   5138  C CD2 . LEU B 1 348 ? 149.422 118.830 156.025 1.00 55.41  ? 294 LEU B CD2 1 
ATOM   5139  N N   . ALA B 1 349 ? 146.768 123.391 156.931 1.00 59.37  ? 295 ALA B N   1 
ATOM   5140  C CA  . ALA B 1 349 ? 146.308 124.335 157.950 1.00 54.77  ? 295 ALA B CA  1 
ATOM   5141  C C   . ALA B 1 349 ? 145.132 123.768 158.745 1.00 61.00  ? 295 ALA B C   1 
ATOM   5142  O O   . ALA B 1 349 ? 145.129 123.804 159.986 1.00 68.93  ? 295 ALA B O   1 
ATOM   5143  C CB  . ALA B 1 349 ? 145.925 125.663 157.300 1.00 56.56  ? 295 ALA B CB  1 
ATOM   5144  N N   . LEU B 1 350 ? 144.129 123.229 158.048 1.00 53.83  ? 296 LEU B N   1 
ATOM   5145  C CA  . LEU B 1 350 ? 142.987 122.627 158.728 1.00 51.36  ? 296 LEU B CA  1 
ATOM   5146  C C   . LEU B 1 350 ? 143.394 121.392 159.522 1.00 61.99  ? 296 LEU B C   1 
ATOM   5147  O O   . LEU B 1 350 ? 142.897 121.177 160.636 1.00 64.22  ? 296 LEU B O   1 
ATOM   5148  C CB  . LEU B 1 350 ? 141.901 122.276 157.712 1.00 48.42  ? 296 LEU B CB  1 
ATOM   5149  C CG  . LEU B 1 350 ? 140.637 121.612 158.258 1.00 47.53  ? 296 LEU B CG  1 
ATOM   5150  C CD1 . LEU B 1 350 ? 139.965 122.508 159.283 1.00 47.91  ? 296 LEU B CD1 1 
ATOM   5151  C CD2 . LEU B 1 350 ? 139.681 121.276 157.126 1.00 52.08  ? 296 LEU B CD2 1 
ATOM   5152  N N   . LEU B 1 351 ? 144.287 120.568 158.971 1.00 65.78  ? 297 LEU B N   1 
ATOM   5153  C CA  . LEU B 1 351 ? 144.783 119.426 159.727 1.00 63.24  ? 297 LEU B CA  1 
ATOM   5154  C C   . LEU B 1 351 ? 145.617 119.849 160.928 1.00 65.24  ? 297 LEU B C   1 
ATOM   5155  O O   . LEU B 1 351 ? 145.661 119.119 161.916 1.00 72.61  ? 297 LEU B O   1 
ATOM   5156  C CB  . LEU B 1 351 ? 145.593 118.497 158.826 1.00 59.45  ? 297 LEU B CB  1 
ATOM   5157  C CG  . LEU B 1 351 ? 144.763 117.673 157.843 1.00 59.60  ? 297 LEU B CG  1 
ATOM   5158  C CD1 . LEU B 1 351 ? 145.628 116.629 157.160 1.00 67.28  ? 297 LEU B CD1 1 
ATOM   5159  C CD2 . LEU B 1 351 ? 143.589 117.020 158.556 1.00 56.32  ? 297 LEU B CD2 1 
ATOM   5160  N N   . GLU B 1 352 ? 146.256 121.019 160.881 1.00 62.60  ? 298 GLU B N   1 
ATOM   5161  C CA  . GLU B 1 352 ? 146.949 121.528 162.058 1.00 65.69  ? 298 GLU B CA  1 
ATOM   5162  C C   . GLU B 1 352 ? 145.957 121.975 163.121 1.00 64.62  ? 298 GLU B C   1 
ATOM   5163  O O   . GLU B 1 352 ? 146.193 121.782 164.318 1.00 69.00  ? 298 GLU B O   1 
ATOM   5164  C CB  . GLU B 1 352 ? 147.878 122.677 161.666 1.00 68.10  ? 298 GLU B CB  1 
ATOM   5165  C CG  . GLU B 1 352 ? 148.853 123.099 162.756 1.00 65.93  ? 298 GLU B CG  1 
ATOM   5166  C CD  . GLU B 1 352 ? 148.367 124.287 163.565 1.00 73.64  ? 298 GLU B CD  1 
ATOM   5167  O OE1 . GLU B 1 352 ? 147.167 124.623 163.486 1.00 68.40  ? 298 GLU B OE1 1 
ATOM   5168  O OE2 . GLU B 1 352 ? 149.193 124.895 164.277 1.00 84.55  ? 298 GLU B OE2 1 
ATOM   5169  N N   . TYR B 1 353 ? 144.846 122.583 162.704 1.00 64.72  ? 299 TYR B N   1 
ATOM   5170  C CA  . TYR B 1 353 ? 143.793 122.892 163.670 1.00 68.12  ? 299 TYR B CA  1 
ATOM   5171  C C   . TYR B 1 353 ? 143.248 121.618 164.308 1.00 71.48  ? 299 TYR B C   1 
ATOM   5172  O O   . TYR B 1 353 ? 143.022 121.566 165.526 1.00 80.34  ? 299 TYR B O   1 
ATOM   5173  C CB  . TYR B 1 353 ? 142.668 123.684 163.005 1.00 68.99  ? 299 TYR B CB  1 
ATOM   5174  C CG  . TYR B 1 353 ? 141.502 123.970 163.928 1.00 76.64  ? 299 TYR B CG  1 
ATOM   5175  C CD1 . TYR B 1 353 ? 141.702 124.557 165.170 1.00 78.50  ? 299 TYR B CD1 1 
ATOM   5176  C CD2 . TYR B 1 353 ? 140.201 123.661 163.553 1.00 73.42  ? 299 TYR B CD2 1 
ATOM   5177  C CE1 . TYR B 1 353 ? 140.641 124.821 166.015 1.00 75.42  ? 299 TYR B CE1 1 
ATOM   5178  C CE2 . TYR B 1 353 ? 139.134 123.925 164.391 1.00 73.61  ? 299 TYR B CE2 1 
ATOM   5179  C CZ  . TYR B 1 353 ? 139.361 124.504 165.621 1.00 74.69  ? 299 TYR B CZ  1 
ATOM   5180  O OH  . TYR B 1 353 ? 138.304 124.768 166.460 1.00 74.37  ? 299 TYR B OH  1 
ATOM   5181  N N   . ALA B 1 354 ? 143.038 120.577 163.501 1.00 66.46  ? 300 ALA B N   1 
ATOM   5182  C CA  . ALA B 1 354 ? 142.602 119.293 164.044 1.00 65.18  ? 300 ALA B CA  1 
ATOM   5183  C C   . ALA B 1 354 ? 143.652 118.702 164.979 1.00 70.96  ? 300 ALA B C   1 
ATOM   5184  O O   . ALA B 1 354 ? 143.317 118.106 166.007 1.00 76.04  ? 300 ALA B O   1 
ATOM   5185  C CB  . ALA B 1 354 ? 142.284 118.322 162.909 1.00 68.66  ? 300 ALA B CB  1 
ATOM   5186  N N   . PHE B 1 355 ? 144.930 118.852 164.631 1.00 71.52  ? 301 PHE B N   1 
ATOM   5187  C CA  . PHE B 1 355 ? 146.013 118.364 165.477 1.00 76.14  ? 301 PHE B CA  1 
ATOM   5188  C C   . PHE B 1 355 ? 146.021 119.076 166.823 1.00 83.50  ? 301 PHE B C   1 
ATOM   5189  O O   . PHE B 1 355 ? 146.264 118.456 167.866 1.00 88.77  ? 301 PHE B O   1 
ATOM   5190  C CB  . PHE B 1 355 ? 147.344 118.559 164.750 1.00 73.45  ? 301 PHE B CB  1 
ATOM   5191  C CG  . PHE B 1 355 ? 148.489 117.801 165.349 1.00 82.92  ? 301 PHE B CG  1 
ATOM   5192  C CD1 . PHE B 1 355 ? 148.758 116.504 164.949 1.00 88.38  ? 301 PHE B CD1 1 
ATOM   5193  C CD2 . PHE B 1 355 ? 149.312 118.391 166.292 1.00 87.96  ? 301 PHE B CD2 1 
ATOM   5194  C CE1 . PHE B 1 355 ? 149.817 115.804 165.490 1.00 95.79  ? 301 PHE B CE1 1 
ATOM   5195  C CE2 . PHE B 1 355 ? 150.372 117.697 166.837 1.00 93.21  ? 301 PHE B CE2 1 
ATOM   5196  C CZ  . PHE B 1 355 ? 150.625 116.401 166.435 1.00 94.90  ? 301 PHE B CZ  1 
ATOM   5197  N N   . VAL B 1 356 ? 145.778 120.387 166.812 1.00 82.46  ? 302 VAL B N   1 
ATOM   5198  C CA  . VAL B 1 356 ? 145.687 121.147 168.055 1.00 80.13  ? 302 VAL B CA  1 
ATOM   5199  C C   . VAL B 1 356 ? 144.505 120.663 168.883 1.00 82.62  ? 302 VAL B C   1 
ATOM   5200  O O   . VAL B 1 356 ? 144.619 120.455 170.095 1.00 87.03  ? 302 VAL B O   1 
ATOM   5201  C CB  . VAL B 1 356 ? 145.593 122.654 167.756 1.00 79.95  ? 302 VAL B CB  1 
ATOM   5202  C CG1 . VAL B 1 356 ? 144.903 123.384 168.894 1.00 82.65  ? 302 VAL B CG1 1 
ATOM   5203  C CG2 . VAL B 1 356 ? 146.977 123.226 167.527 1.00 84.01  ? 302 VAL B CG2 1 
ATOM   5204  N N   . ASN B 1 357 ? 143.352 120.470 168.239 1.00 86.94  ? 303 ASN B N   1 
ATOM   5205  C CA  . ASN B 1 357 ? 142.183 119.973 168.960 1.00 89.53  ? 303 ASN B CA  1 
ATOM   5206  C C   . ASN B 1 357 ? 142.375 118.549 169.468 1.00 91.64  ? 303 ASN B C   1 
ATOM   5207  O O   . ASN B 1 357 ? 141.690 118.141 170.413 1.00 91.54  ? 303 ASN B O   1 
ATOM   5208  C CB  . ASN B 1 357 ? 140.943 120.049 168.070 1.00 85.49  ? 303 ASN B CB  1 
ATOM   5209  C CG  . ASN B 1 357 ? 140.114 121.288 168.334 1.00 83.15  ? 303 ASN B CG  1 
ATOM   5210  O OD1 . ASN B 1 357 ? 138.928 121.200 168.649 1.00 88.46  ? 303 ASN B OD1 1 
ATOM   5211  N ND2 . ASN B 1 357 ? 140.739 122.453 168.221 1.00 77.72  ? 303 ASN B ND2 1 
ATOM   5212  N N   . TYR B 1 358 ? 143.284 117.785 168.862 1.00 93.26  ? 304 TYR B N   1 
ATOM   5213  C CA  . TYR B 1 358 ? 143.537 116.421 169.313 1.00 94.08  ? 304 TYR B CA  1 
ATOM   5214  C C   . TYR B 1 358 ? 144.503 116.391 170.490 1.00 97.75  ? 304 TYR B C   1 
ATOM   5215  O O   . TYR B 1 358 ? 144.198 115.809 171.537 1.00 101.13 ? 304 TYR B O   1 
ATOM   5216  C CB  . TYR B 1 358 ? 144.076 115.577 168.157 1.00 97.54  ? 304 TYR B CB  1 
ATOM   5217  C CG  . TYR B 1 358 ? 144.722 114.283 168.593 1.00 100.45 ? 304 TYR B CG  1 
ATOM   5218  C CD1 . TYR B 1 358 ? 143.963 113.249 169.123 1.00 101.01 ? 304 TYR B CD1 1 
ATOM   5219  C CD2 . TYR B 1 358 ? 146.091 114.091 168.467 1.00 104.34 ? 304 TYR B CD2 1 
ATOM   5220  C CE1 . TYR B 1 358 ? 144.551 112.063 169.520 1.00 107.31 ? 304 TYR B CE1 1 
ATOM   5221  C CE2 . TYR B 1 358 ? 146.686 112.910 168.861 1.00 108.24 ? 304 TYR B CE2 1 
ATOM   5222  C CZ  . TYR B 1 358 ? 145.912 111.899 169.386 1.00 110.67 ? 304 TYR B CZ  1 
ATOM   5223  O OH  . TYR B 1 358 ? 146.503 110.721 169.779 1.00 106.48 ? 304 TYR B OH  1 
ATOM   5224  N N   . ILE B 1 359 ? 145.676 117.013 170.340 1.00 99.97  ? 305 ILE B N   1 
ATOM   5225  C CA  . ILE B 1 359 ? 146.645 117.023 171.430 1.00 104.36 ? 305 ILE B CA  1 
ATOM   5226  C C   . ILE B 1 359 ? 146.253 118.009 172.521 1.00 109.49 ? 305 ILE B C   1 
ATOM   5227  O O   . ILE B 1 359 ? 146.950 118.117 173.535 1.00 110.81 ? 305 ILE B O   1 
ATOM   5228  C CB  . ILE B 1 359 ? 148.060 117.339 170.914 1.00 98.30  ? 305 ILE B CB  1 
ATOM   5229  C CG1 . ILE B 1 359 ? 148.136 118.782 170.420 1.00 100.85 ? 305 ILE B CG1 1 
ATOM   5230  C CG2 . ILE B 1 359 ? 148.455 116.368 169.815 1.00 95.07  ? 305 ILE B CG2 1 
ATOM   5231  C CD1 . ILE B 1 359 ? 149.510 119.188 169.963 1.00 101.83 ? 305 ILE B CD1 1 
ATOM   5232  N N   . PHE B 1 360 ? 145.152 118.737 172.334 1.00 109.00 ? 306 PHE B N   1 
ATOM   5233  C CA  . PHE B 1 360 ? 144.654 119.622 173.380 1.00 113.06 ? 306 PHE B CA  1 
ATOM   5234  C C   . PHE B 1 360 ? 144.029 118.828 174.516 1.00 119.16 ? 306 PHE B C   1 
ATOM   5235  O O   . PHE B 1 360 ? 143.981 119.304 175.657 1.00 121.12 ? 306 PHE B O   1 
ATOM   5236  C CB  . PHE B 1 360 ? 143.649 120.604 172.777 1.00 107.10 ? 306 PHE B CB  1 
ATOM   5237  C CG  . PHE B 1 360 ? 143.044 121.549 173.770 1.00 114.96 ? 306 PHE B CG  1 
ATOM   5238  C CD1 . PHE B 1 360 ? 143.837 122.447 174.466 1.00 120.18 ? 306 PHE B CD1 1 
ATOM   5239  C CD2 . PHE B 1 360 ? 141.678 121.557 173.991 1.00 116.60 ? 306 PHE B CD2 1 
ATOM   5240  C CE1 . PHE B 1 360 ? 143.279 123.323 175.375 1.00 122.96 ? 306 PHE B CE1 1 
ATOM   5241  C CE2 . PHE B 1 360 ? 141.114 122.432 174.898 1.00 120.48 ? 306 PHE B CE2 1 
ATOM   5242  C CZ  . PHE B 1 360 ? 141.915 123.316 175.591 1.00 125.04 ? 306 PHE B CZ  1 
ATOM   5243  N N   . PHE B 1 361 ? 143.540 117.622 174.221 1.00 121.29 ? 307 PHE B N   1 
ATOM   5244  C CA  . PHE B 1 361 ? 143.018 116.747 175.264 1.00 130.36 ? 307 PHE B CA  1 
ATOM   5245  C C   . PHE B 1 361 ? 144.108 116.350 176.253 1.00 133.13 ? 307 PHE B C   1 
ATOM   5246  O O   . PHE B 1 361 ? 143.881 116.342 177.468 1.00 134.32 ? 307 PHE B O   1 
ATOM   5247  C CB  . PHE B 1 361 ? 142.382 115.511 174.624 1.00 130.88 ? 307 PHE B CB  1 
ATOM   5248  C CG  . PHE B 1 361 ? 142.453 114.275 175.475 1.00 138.26 ? 307 PHE B CG  1 
ATOM   5249  C CD1 . PHE B 1 361 ? 141.558 114.078 176.512 1.00 137.92 ? 307 PHE B CD1 1 
ATOM   5250  C CD2 . PHE B 1 361 ? 143.406 113.299 175.225 1.00 138.07 ? 307 PHE B CD2 1 
ATOM   5251  C CE1 . PHE B 1 361 ? 141.619 112.938 177.292 1.00 137.30 ? 307 PHE B CE1 1 
ATOM   5252  C CE2 . PHE B 1 361 ? 143.473 112.159 176.001 1.00 135.58 ? 307 PHE B CE2 1 
ATOM   5253  C CZ  . PHE B 1 361 ? 142.578 111.977 177.035 1.00 135.47 ? 307 PHE B CZ  1 
ATOM   5254  N N   . SER B 1 362 ? 145.298 116.017 175.751 1.00 129.71 ? 308 SER B N   1 
ATOM   5255  C CA  . SER B 1 362 ? 146.375 115.565 176.626 1.00 126.97 ? 308 SER B CA  1 
ATOM   5256  C C   . SER B 1 362 ? 146.988 116.726 177.404 1.00 129.95 ? 308 SER B C   1 
ATOM   5257  O O   . SER B 1 362 ? 146.954 116.747 178.639 1.00 134.17 ? 308 SER B O   1 
ATOM   5258  C CB  . SER B 1 362 ? 147.449 114.843 175.809 1.00 121.83 ? 308 SER B CB  1 
ATOM   5259  O OG  . SER B 1 362 ? 148.180 115.758 175.013 1.00 125.56 ? 308 SER B OG  1 
ATOM   5260  N N   . GLN B 1 363 ? 147.555 117.701 176.694 1.00 128.26 ? 309 GLN B N   1 
ATOM   5261  C CA  . GLN B 1 363 ? 148.226 118.828 177.324 1.00 127.45 ? 309 GLN B CA  1 
ATOM   5262  C C   . GLN B 1 363 ? 147.792 120.124 176.649 1.00 129.13 ? 309 GLN B C   1 
ATOM   5263  O O   . GLN B 1 363 ? 147.743 120.191 175.409 1.00 127.59 ? 309 GLN B O   1 
ATOM   5264  C CB  . GLN B 1 363 ? 149.750 118.674 177.246 1.00 123.90 ? 309 GLN B CB  1 
ATOM   5265  C CG  . GLN B 1 363 ? 150.289 117.456 177.974 1.00 134.74 ? 309 GLN B CG  1 
ATOM   5266  C CD  . GLN B 1 363 ? 151.787 117.300 177.814 1.00 140.17 ? 309 GLN B CD  1 
ATOM   5267  O OE1 . GLN B 1 363 ? 152.418 118.021 177.039 1.00 136.34 ? 309 GLN B OE1 1 
ATOM   5268  N NE2 . GLN B 1 363 ? 152.366 116.357 178.548 1.00 138.92 ? 309 GLN B NE2 1 
ATOM   5269  N N   . PRO B 1 364 ? 147.474 121.170 177.418 1.00 127.44 ? 310 PRO B N   1 
ATOM   5270  C CA  . PRO B 1 364 ? 147.119 122.457 176.806 1.00 124.46 ? 310 PRO B CA  1 
ATOM   5271  C C   . PRO B 1 364 ? 148.313 123.306 176.406 1.00 121.55 ? 310 PRO B C   1 
ATOM   5272  O O   . PRO B 1 364 ? 148.177 124.139 175.500 1.00 118.90 ? 310 PRO B O   1 
ATOM   5273  C CB  . PRO B 1 364 ? 146.307 123.145 177.908 1.00 123.32 ? 310 PRO B CB  1 
ATOM   5274  C CG  . PRO B 1 364 ? 146.890 122.605 179.170 1.00 123.65 ? 310 PRO B CG  1 
ATOM   5275  C CD  . PRO B 1 364 ? 147.279 121.177 178.878 1.00 124.50 ? 310 PRO B CD  1 
ATOM   5276  N N   . ALA B 1 365 ? 149.469 123.136 177.050 1.00 118.26 ? 311 ALA B N   1 
ATOM   5277  C CA  . ALA B 1 365 ? 150.661 123.891 176.682 1.00 114.75 ? 311 ALA B CA  1 
ATOM   5278  C C   . ALA B 1 365 ? 151.148 123.550 175.280 1.00 111.51 ? 311 ALA B C   1 
ATOM   5279  O O   . ALA B 1 365 ? 151.524 124.449 174.517 1.00 109.61 ? 311 ALA B O   1 
ATOM   5280  C CB  . ALA B 1 365 ? 151.779 123.641 177.698 1.00 112.59 ? 311 ALA B CB  1 
ATOM   5281  N N   . ARG B 1 366 ? 151.144 122.264 174.925 1.00 112.17 ? 312 ARG B N   1 
ATOM   5282  C CA  . ARG B 1 366 ? 151.558 121.875 173.583 1.00 108.94 ? 312 ARG B CA  1 
ATOM   5283  C C   . ARG B 1 366 ? 150.588 122.392 172.530 1.00 108.63 ? 312 ARG B C   1 
ATOM   5284  O O   . ARG B 1 366 ? 150.992 122.636 171.388 1.00 113.23 ? 312 ARG B O   1 
ATOM   5285  C CB  . ARG B 1 366 ? 151.693 120.355 173.491 1.00 116.74 ? 312 ARG B CB  1 
ATOM   5286  C CG  . ARG B 1 366 ? 152.380 119.876 172.223 1.00 110.57 ? 312 ARG B CG  1 
ATOM   5287  C CD  . ARG B 1 366 ? 152.823 118.429 172.339 1.00 112.95 ? 312 ARG B CD  1 
ATOM   5288  N NE  . ARG B 1 366 ? 153.583 118.002 171.171 1.00 111.50 ? 312 ARG B NE  1 
ATOM   5289  C CZ  . ARG B 1 366 ? 154.208 116.837 171.069 1.00 114.80 ? 312 ARG B CZ  1 
ATOM   5290  N NH1 . ARG B 1 366 ? 154.190 115.954 172.054 1.00 111.73 ? 312 ARG B NH1 1 
ATOM   5291  N NH2 . ARG B 1 366 ? 154.871 116.552 169.951 1.00 117.21 ? 312 ARG B NH2 1 
ATOM   5292  N N   . ALA B 1 367 ? 149.318 122.589 172.895 1.00 108.26 ? 313 ALA B N   1 
ATOM   5293  C CA  . ALA B 1 367 ? 148.357 123.146 171.949 1.00 110.22 ? 313 ALA B CA  1 
ATOM   5294  C C   . ALA B 1 367 ? 148.756 124.546 171.501 1.00 107.89 ? 313 ALA B C   1 
ATOM   5295  O O   . ALA B 1 367 ? 148.667 124.864 170.310 1.00 102.53 ? 313 ALA B O   1 
ATOM   5296  C CB  . ALA B 1 367 ? 146.960 123.165 172.568 1.00 110.19 ? 313 ALA B CB  1 
ATOM   5297  N N   . ALA B 1 368 ? 149.195 125.392 172.432 1.00 109.34 ? 314 ALA B N   1 
ATOM   5298  C CA  . ALA B 1 368 ? 149.693 126.716 172.085 1.00 104.30 ? 314 ALA B CA  1 
ATOM   5299  C C   . ALA B 1 368 ? 151.091 126.682 171.487 1.00 103.18 ? 314 ALA B C   1 
ATOM   5300  O O   . ALA B 1 368 ? 151.407 127.517 170.628 1.00 102.03 ? 314 ALA B O   1 
ATOM   5301  C CB  . ALA B 1 368 ? 149.687 127.625 173.317 1.00 104.97 ? 314 ALA B CB  1 
ATOM   5302  N N   . ALA B 1 369 ? 151.932 125.739 171.919 1.00 101.99 ? 422 ALA B N   1 
ATOM   5303  C CA  . ALA B 1 369 ? 153.263 125.613 171.333 1.00 99.35  ? 422 ALA B CA  1 
ATOM   5304  C C   . ALA B 1 369 ? 153.184 125.250 169.856 1.00 95.93  ? 422 ALA B C   1 
ATOM   5305  O O   . ALA B 1 369 ? 153.995 125.722 169.052 1.00 90.57  ? 422 ALA B O   1 
ATOM   5306  C CB  . ALA B 1 369 ? 154.080 124.574 172.101 1.00 99.52  ? 422 ALA B CB  1 
ATOM   5307  N N   . ILE B 1 370 ? 152.218 124.409 169.481 1.00 100.47 ? 423 ILE B N   1 
ATOM   5308  C CA  . ILE B 1 370 ? 152.059 124.029 168.080 1.00 97.84  ? 423 ILE B CA  1 
ATOM   5309  C C   . ILE B 1 370 ? 151.709 125.246 167.234 1.00 92.72  ? 423 ILE B C   1 
ATOM   5310  O O   . ILE B 1 370 ? 152.247 125.431 166.139 1.00 92.88  ? 423 ILE B O   1 
ATOM   5311  C CB  . ILE B 1 370 ? 151.007 122.915 167.938 1.00 92.39  ? 423 ILE B CB  1 
ATOM   5312  C CG1 . ILE B 1 370 ? 151.610 121.570 168.337 1.00 93.58  ? 423 ILE B CG1 1 
ATOM   5313  C CG2 . ILE B 1 370 ? 150.487 122.846 166.515 1.00 87.87  ? 423 ILE B CG2 1 
ATOM   5314  C CD1 . ILE B 1 370 ? 152.733 121.119 167.431 1.00 95.86  ? 423 ILE B CD1 1 
ATOM   5315  N N   . ASP B 1 371 ? 150.801 126.092 167.725 1.00 90.62  ? 424 ASP B N   1 
ATOM   5316  C CA  . ASP B 1 371 ? 150.458 127.308 166.991 1.00 87.68  ? 424 ASP B CA  1 
ATOM   5317  C C   . ASP B 1 371 ? 151.653 128.250 166.897 1.00 87.24  ? 424 ASP B C   1 
ATOM   5318  O O   . ASP B 1 371 ? 151.923 128.832 165.836 1.00 87.16  ? 424 ASP B O   1 
ATOM   5319  C CB  . ASP B 1 371 ? 149.273 128.008 167.656 1.00 91.18  ? 424 ASP B CB  1 
ATOM   5320  C CG  . ASP B 1 371 ? 147.979 127.246 167.481 1.00 92.96  ? 424 ASP B CG  1 
ATOM   5321  O OD1 . ASP B 1 371 ? 148.006 126.178 166.837 1.00 94.01  ? 424 ASP B OD1 1 
ATOM   5322  O OD2 . ASP B 1 371 ? 146.936 127.715 167.984 1.00 96.94  ? 424 ASP B OD2 1 
ATOM   5323  N N   . ARG B 1 372 ? 152.382 128.413 168.004 1.00 87.27  ? 425 ARG B N   1 
ATOM   5324  C CA  . ARG B 1 372 ? 153.548 129.291 167.994 1.00 85.88  ? 425 ARG B CA  1 
ATOM   5325  C C   . ARG B 1 372 ? 154.583 128.810 166.986 1.00 89.08  ? 425 ARG B C   1 
ATOM   5326  O O   . ARG B 1 372 ? 155.193 129.613 166.271 1.00 89.70  ? 425 ARG B O   1 
ATOM   5327  C CB  . ARG B 1 372 ? 154.156 129.379 169.394 1.00 91.80  ? 425 ARG B CB  1 
ATOM   5328  C CG  . ARG B 1 372 ? 153.308 130.147 170.390 1.00 96.70  ? 425 ARG B CG  1 
ATOM   5329  C CD  . ARG B 1 372 ? 154.081 130.426 171.667 1.00 105.29 ? 425 ARG B CD  1 
ATOM   5330  N NE  . ARG B 1 372 ? 154.452 129.202 172.366 1.00 112.19 ? 425 ARG B NE  1 
ATOM   5331  C CZ  . ARG B 1 372 ? 153.750 128.665 173.354 1.00 115.93 ? 425 ARG B CZ  1 
ATOM   5332  N NH1 . ARG B 1 372 ? 152.630 129.220 173.788 1.00 115.99 ? 425 ARG B NH1 1 
ATOM   5333  N NH2 . ARG B 1 372 ? 154.183 127.543 173.923 1.00 113.29 ? 425 ARG B NH2 1 
ATOM   5334  N N   . TRP B 1 373 ? 154.793 127.495 166.915 1.00 90.89  ? 426 TRP B N   1 
ATOM   5335  C CA  . TRP B 1 373 ? 155.741 126.953 165.948 1.00 89.93  ? 426 TRP B CA  1 
ATOM   5336  C C   . TRP B 1 373 ? 155.207 127.054 164.524 1.00 87.61  ? 426 TRP B C   1 
ATOM   5337  O O   . TRP B 1 373 ? 155.974 127.305 163.590 1.00 86.53  ? 426 TRP B O   1 
ATOM   5338  C CB  . TRP B 1 373 ? 156.078 125.505 166.298 1.00 88.44  ? 426 TRP B CB  1 
ATOM   5339  C CG  . TRP B 1 373 ? 157.286 125.374 167.167 1.00 94.96  ? 426 TRP B CG  1 
ATOM   5340  C CD1 . TRP B 1 373 ? 157.318 125.338 168.530 1.00 98.17  ? 426 TRP B CD1 1 
ATOM   5341  C CD2 . TRP B 1 373 ? 158.646 125.267 166.731 1.00 97.88  ? 426 TRP B CD2 1 
ATOM   5342  N NE1 . TRP B 1 373 ? 158.614 125.212 168.970 1.00 96.35  ? 426 TRP B NE1 1 
ATOM   5343  C CE2 . TRP B 1 373 ? 159.448 125.166 167.884 1.00 97.05  ? 426 TRP B CE2 1 
ATOM   5344  C CE3 . TRP B 1 373 ? 159.262 125.244 165.476 1.00 97.10  ? 426 TRP B CE3 1 
ATOM   5345  C CZ2 . TRP B 1 373 ? 160.834 125.045 167.820 1.00 95.11  ? 426 TRP B CZ2 1 
ATOM   5346  C CZ3 . TRP B 1 373 ? 160.637 125.124 165.415 1.00 95.41  ? 426 TRP B CZ3 1 
ATOM   5347  C CH2 . TRP B 1 373 ? 161.408 125.026 166.579 1.00 92.57  ? 426 TRP B CH2 1 
ATOM   5348  N N   . SER B 1 374 ? 153.899 126.861 164.337 1.00 85.42  ? 427 SER B N   1 
ATOM   5349  C CA  . SER B 1 374 ? 153.314 126.899 163.000 1.00 76.40  ? 427 SER B CA  1 
ATOM   5350  C C   . SER B 1 374 ? 153.422 128.289 162.394 1.00 73.11  ? 427 SER B C   1 
ATOM   5351  O O   . SER B 1 374 ? 153.661 128.436 161.189 1.00 72.60  ? 427 SER B O   1 
ATOM   5352  C CB  . SER B 1 374 ? 151.853 126.450 163.052 1.00 73.75  ? 427 SER B CB  1 
ATOM   5353  O OG  . SER B 1 374 ? 151.740 125.131 163.555 1.00 77.51  ? 427 SER B OG  1 
ATOM   5354  N N   . ARG B 1 375 ? 153.273 129.323 163.231 1.00 71.78  ? 428 ARG B N   1 
ATOM   5355  C CA  . ARG B 1 375 ? 153.371 130.697 162.745 1.00 72.75  ? 428 ARG B CA  1 
ATOM   5356  C C   . ARG B 1 375 ? 154.695 130.952 162.040 1.00 76.06  ? 428 ARG B C   1 
ATOM   5357  O O   . ARG B 1 375 ? 154.784 131.839 161.184 1.00 78.60  ? 428 ARG B O   1 
ATOM   5358  C CB  . ARG B 1 375 ? 153.215 131.685 163.901 1.00 79.42  ? 428 ARG B CB  1 
ATOM   5359  C CG  . ARG B 1 375 ? 151.857 131.685 164.572 1.00 80.53  ? 428 ARG B CG  1 
ATOM   5360  C CD  . ARG B 1 375 ? 151.926 132.431 165.894 1.00 78.00  ? 428 ARG B CD  1 
ATOM   5361  N NE  . ARG B 1 375 ? 150.692 132.323 166.661 1.00 80.37  ? 428 ARG B NE  1 
ATOM   5362  C CZ  . ARG B 1 375 ? 150.574 132.671 167.935 1.00 82.69  ? 428 ARG B CZ  1 
ATOM   5363  N NH1 . ARG B 1 375 ? 151.604 133.139 168.621 1.00 83.15  ? 428 ARG B NH1 1 
ATOM   5364  N NH2 . ARG B 1 375 ? 149.395 132.542 168.537 1.00 82.41  ? 428 ARG B NH2 1 
ATOM   5365  N N   . ILE B 1 376 ? 155.732 130.199 162.392 1.00 72.40  ? 429 ILE B N   1 
ATOM   5366  C CA  . ILE B 1 376 ? 157.028 130.299 161.738 1.00 69.76  ? 429 ILE B CA  1 
ATOM   5367  C C   . ILE B 1 376 ? 157.199 129.232 160.662 1.00 73.53  ? 429 ILE B C   1 
ATOM   5368  O O   . ILE B 1 376 ? 157.781 129.498 159.610 1.00 79.62  ? 429 ILE B O   1 
ATOM   5369  C CB  . ILE B 1 376 ? 158.155 130.215 162.790 1.00 72.61  ? 429 ILE B CB  1 
ATOM   5370  C CG1 . ILE B 1 376 ? 157.935 131.256 163.889 1.00 80.66  ? 429 ILE B CG1 1 
ATOM   5371  C CG2 . ILE B 1 376 ? 159.512 130.409 162.139 1.00 76.54  ? 429 ILE B CG2 1 
ATOM   5372  C CD1 . ILE B 1 376 ? 158.925 131.158 165.032 1.00 78.90  ? 429 ILE B CD1 1 
ATOM   5373  N N   . VAL B 1 377 ? 156.690 128.023 160.909 1.00 74.52  ? 430 VAL B N   1 
ATOM   5374  C CA  . VAL B 1 377 ? 156.934 126.905 160.002 1.00 71.14  ? 430 VAL B CA  1 
ATOM   5375  C C   . VAL B 1 377 ? 156.214 127.113 158.675 1.00 69.21  ? 430 VAL B C   1 
ATOM   5376  O O   . VAL B 1 377 ? 156.807 126.956 157.602 1.00 67.52  ? 430 VAL B O   1 
ATOM   5377  C CB  . VAL B 1 377 ? 156.520 125.577 160.661 1.00 65.96  ? 430 VAL B CB  1 
ATOM   5378  C CG1 . VAL B 1 377 ? 156.419 124.478 159.619 1.00 58.20  ? 430 VAL B CG1 1 
ATOM   5379  C CG2 . VAL B 1 377 ? 157.518 125.193 161.734 1.00 70.27  ? 430 VAL B CG2 1 
ATOM   5380  N N   . PHE B 1 378 ? 154.927 127.459 158.723 1.00 66.21  ? 431 PHE B N   1 
ATOM   5381  C CA  . PHE B 1 378 ? 154.158 127.552 157.483 1.00 60.26  ? 431 PHE B CA  1 
ATOM   5382  C C   . PHE B 1 378 ? 154.688 128.623 156.538 1.00 60.07  ? 431 PHE B C   1 
ATOM   5383  O O   . PHE B 1 378 ? 154.882 128.318 155.348 1.00 64.02  ? 431 PHE B O   1 
ATOM   5384  C CB  . PHE B 1 378 ? 152.674 127.752 157.803 1.00 56.94  ? 431 PHE B CB  1 
ATOM   5385  C CG  . PHE B 1 378 ? 151.943 126.474 158.089 1.00 56.09  ? 431 PHE B CG  1 
ATOM   5386  C CD1 . PHE B 1 378 ? 151.975 125.910 159.351 1.00 61.24  ? 431 PHE B CD1 1 
ATOM   5387  C CD2 . PHE B 1 378 ? 151.229 125.834 157.092 1.00 55.93  ? 431 PHE B CD2 1 
ATOM   5388  C CE1 . PHE B 1 378 ? 151.305 124.734 159.615 1.00 64.70  ? 431 PHE B CE1 1 
ATOM   5389  C CE2 . PHE B 1 378 ? 150.557 124.658 157.349 1.00 57.13  ? 431 PHE B CE2 1 
ATOM   5390  C CZ  . PHE B 1 378 ? 150.595 124.107 158.612 1.00 58.86  ? 431 PHE B CZ  1 
ATOM   5391  N N   . PRO B 1 379 ? 154.940 129.867 156.968 1.00 58.06  ? 432 PRO B N   1 
ATOM   5392  C CA  . PRO B 1 379 ? 155.546 130.828 156.032 1.00 60.13  ? 432 PRO B CA  1 
ATOM   5393  C C   . PRO B 1 379 ? 156.890 130.377 155.491 1.00 65.73  ? 432 PRO B C   1 
ATOM   5394  O O   . PRO B 1 379 ? 157.156 130.549 154.297 1.00 71.07  ? 432 PRO B O   1 
ATOM   5395  C CB  . PRO B 1 379 ? 155.669 132.104 156.876 1.00 65.09  ? 432 PRO B CB  1 
ATOM   5396  C CG  . PRO B 1 379 ? 154.623 131.968 157.911 1.00 65.41  ? 432 PRO B CG  1 
ATOM   5397  C CD  . PRO B 1 379 ? 154.597 130.511 158.249 1.00 64.28  ? 432 PRO B CD  1 
ATOM   5398  N N   . PHE B 1 380 ? 157.735 129.771 156.328 1.00 65.98  ? 433 PHE B N   1 
ATOM   5399  C CA  . PHE B 1 380 ? 159.054 129.348 155.866 1.00 70.19  ? 433 PHE B CA  1 
ATOM   5400  C C   . PHE B 1 380 ? 158.951 128.205 154.865 1.00 71.27  ? 433 PHE B C   1 
ATOM   5401  O O   . PHE B 1 380 ? 159.643 128.203 153.838 1.00 74.11  ? 433 PHE B O   1 
ATOM   5402  C CB  . PHE B 1 380 ? 159.920 128.943 157.058 1.00 75.76  ? 433 PHE B CB  1 
ATOM   5403  C CG  . PHE B 1 380 ? 161.293 128.471 156.678 1.00 79.81  ? 433 PHE B CG  1 
ATOM   5404  C CD1 . PHE B 1 380 ? 162.310 129.379 156.441 1.00 83.33  ? 433 PHE B CD1 1 
ATOM   5405  C CD2 . PHE B 1 380 ? 161.570 127.118 156.567 1.00 80.86  ? 433 PHE B CD2 1 
ATOM   5406  C CE1 . PHE B 1 380 ? 163.575 128.948 156.095 1.00 90.83  ? 433 PHE B CE1 1 
ATOM   5407  C CE2 . PHE B 1 380 ? 162.832 126.681 156.221 1.00 88.89  ? 433 PHE B CE2 1 
ATOM   5408  C CZ  . PHE B 1 380 ? 163.836 127.597 155.985 1.00 95.22  ? 433 PHE B CZ  1 
ATOM   5409  N N   . THR B 1 381 ? 158.094 127.222 155.148 1.00 66.29  ? 434 THR B N   1 
ATOM   5410  C CA  . THR B 1 381 ? 157.914 126.106 154.226 1.00 62.89  ? 434 THR B CA  1 
ATOM   5411  C C   . THR B 1 381 ? 157.329 126.578 152.902 1.00 61.00  ? 434 THR B C   1 
ATOM   5412  O O   . THR B 1 381 ? 157.758 126.133 151.830 1.00 61.97  ? 434 THR B O   1 
ATOM   5413  C CB  . THR B 1 381 ? 157.017 125.043 154.859 1.00 59.37  ? 434 THR B CB  1 
ATOM   5414  O OG1 . THR B 1 381 ? 157.538 124.682 156.143 1.00 64.99  ? 434 THR B OG1 1 
ATOM   5415  C CG2 . THR B 1 381 ? 156.959 123.808 153.980 1.00 55.93  ? 434 THR B CG2 1 
ATOM   5416  N N   . PHE B 1 382 ? 156.351 127.483 152.954 1.00 58.67  ? 435 PHE B N   1 
ATOM   5417  C CA  . PHE B 1 382 ? 155.771 128.010 151.724 1.00 54.60  ? 435 PHE B CA  1 
ATOM   5418  C C   . PHE B 1 382 ? 156.793 128.814 150.935 1.00 55.14  ? 435 PHE B C   1 
ATOM   5419  O O   . PHE B 1 382 ? 156.823 128.754 149.700 1.00 59.12  ? 435 PHE B O   1 
ATOM   5420  C CB  . PHE B 1 382 ? 154.554 128.865 152.053 1.00 58.14  ? 435 PHE B CB  1 
ATOM   5421  C CG  . PHE B 1 382 ? 153.717 129.213 150.863 1.00 59.94  ? 435 PHE B CG  1 
ATOM   5422  C CD1 . PHE B 1 382 ? 153.070 128.225 150.145 1.00 64.14  ? 435 PHE B CD1 1 
ATOM   5423  C CD2 . PHE B 1 382 ? 153.560 130.532 150.471 1.00 61.09  ? 435 PHE B CD2 1 
ATOM   5424  C CE1 . PHE B 1 382 ? 152.293 128.541 149.053 1.00 63.00  ? 435 PHE B CE1 1 
ATOM   5425  C CE2 . PHE B 1 382 ? 152.781 130.854 149.379 1.00 61.23  ? 435 PHE B CE2 1 
ATOM   5426  C CZ  . PHE B 1 382 ? 152.147 129.856 148.669 1.00 57.96  ? 435 PHE B CZ  1 
ATOM   5427  N N   . SER B 1 383 ? 157.636 129.581 151.631 1.00 53.35  ? 436 SER B N   1 
ATOM   5428  C CA  . SER B 1 383 ? 158.682 130.336 150.956 1.00 57.56  ? 436 SER B CA  1 
ATOM   5429  C C   . SER B 1 383 ? 159.674 129.409 150.271 1.00 63.36  ? 436 SER B C   1 
ATOM   5430  O O   . SER B 1 383 ? 160.086 129.663 149.136 1.00 74.02  ? 436 SER B O   1 
ATOM   5431  C CB  . SER B 1 383 ? 159.397 131.244 151.955 1.00 73.43  ? 436 SER B CB  1 
ATOM   5432  O OG  . SER B 1 383 ? 158.499 132.183 152.517 1.00 94.58  ? 436 SER B OG  1 
ATOM   5433  N N   . LEU B 1 384 ? 160.069 128.326 150.945 1.00 59.69  ? 437 LEU B N   1 
ATOM   5434  C CA  . LEU B 1 384 ? 160.976 127.363 150.326 1.00 57.44  ? 437 LEU B CA  1 
ATOM   5435  C C   . LEU B 1 384 ? 160.330 126.693 149.118 1.00 59.44  ? 437 LEU B C   1 
ATOM   5436  O O   . LEU B 1 384 ? 160.985 126.481 148.088 1.00 59.45  ? 437 LEU B O   1 
ATOM   5437  C CB  . LEU B 1 384 ? 161.406 126.318 151.353 1.00 54.74  ? 437 LEU B CB  1 
ATOM   5438  C CG  . LEU B 1 384 ? 162.466 125.311 150.908 1.00 58.37  ? 437 LEU B CG  1 
ATOM   5439  C CD1 . LEU B 1 384 ? 163.774 126.019 150.602 1.00 62.59  ? 437 LEU B CD1 1 
ATOM   5440  C CD2 . LEU B 1 384 ? 162.668 124.241 151.968 1.00 58.67  ? 437 LEU B CD2 1 
ATOM   5441  N N   . PHE B 1 385 ? 159.046 126.344 149.232 1.00 59.39  ? 438 PHE B N   1 
ATOM   5442  C CA  . PHE B 1 385 ? 158.336 125.723 148.119 1.00 57.17  ? 438 PHE B CA  1 
ATOM   5443  C C   . PHE B 1 385 ? 158.282 126.656 146.915 1.00 54.14  ? 438 PHE B C   1 
ATOM   5444  O O   . PHE B 1 385 ? 158.564 126.246 145.783 1.00 58.13  ? 438 PHE B O   1 
ATOM   5445  C CB  . PHE B 1 385 ? 156.928 125.324 148.565 1.00 56.84  ? 438 PHE B CB  1 
ATOM   5446  C CG  . PHE B 1 385 ? 156.029 124.899 147.442 1.00 57.61  ? 438 PHE B CG  1 
ATOM   5447  C CD1 . PHE B 1 385 ? 156.278 123.733 146.740 1.00 58.75  ? 438 PHE B CD1 1 
ATOM   5448  C CD2 . PHE B 1 385 ? 154.923 125.657 147.101 1.00 50.19  ? 438 PHE B CD2 1 
ATOM   5449  C CE1 . PHE B 1 385 ? 155.447 123.340 145.712 1.00 55.37  ? 438 PHE B CE1 1 
ATOM   5450  C CE2 . PHE B 1 385 ? 154.089 125.268 146.076 1.00 44.62  ? 438 PHE B CE2 1 
ATOM   5451  C CZ  . PHE B 1 385 ? 154.352 124.108 145.380 1.00 49.35  ? 438 PHE B CZ  1 
ATOM   5452  N N   . ASN B 1 386 ? 157.937 127.925 147.144 1.00 51.31  ? 439 ASN B N   1 
ATOM   5453  C CA  . ASN B 1 386 ? 157.921 128.893 146.053 1.00 50.03  ? 439 ASN B CA  1 
ATOM   5454  C C   . ASN B 1 386 ? 159.313 129.091 145.472 1.00 54.91  ? 439 ASN B C   1 
ATOM   5455  O O   . ASN B 1 386 ? 159.472 129.212 144.252 1.00 61.71  ? 439 ASN B O   1 
ATOM   5456  C CB  . ASN B 1 386 ? 157.352 130.224 146.536 1.00 51.66  ? 439 ASN B CB  1 
ATOM   5457  C CG  . ASN B 1 386 ? 155.854 130.309 146.365 1.00 56.25  ? 439 ASN B CG  1 
ATOM   5458  O OD1 . ASN B 1 386 ? 155.362 130.703 145.309 1.00 53.27  ? 439 ASN B OD1 1 
ATOM   5459  N ND2 . ASN B 1 386 ? 155.119 129.943 147.404 1.00 58.17  ? 439 ASN B ND2 1 
ATOM   5460  N N   . LEU B 1 387 ? 160.332 129.131 146.330 1.00 54.97  ? 440 LEU B N   1 
ATOM   5461  C CA  . LEU B 1 387 ? 161.701 129.311 145.863 1.00 57.59  ? 440 LEU B CA  1 
ATOM   5462  C C   . LEU B 1 387 ? 162.105 128.195 144.913 1.00 60.76  ? 440 LEU B C   1 
ATOM   5463  O O   . LEU B 1 387 ? 162.567 128.453 143.797 1.00 63.52  ? 440 LEU B O   1 
ATOM   5464  C CB  . LEU B 1 387 ? 162.650 129.368 147.060 1.00 60.41  ? 440 LEU B CB  1 
ATOM   5465  C CG  . LEU B 1 387 ? 164.151 129.335 146.771 1.00 62.07  ? 440 LEU B CG  1 
ATOM   5466  C CD1 . LEU B 1 387 ? 164.626 130.679 146.254 1.00 64.32  ? 440 LEU B CD1 1 
ATOM   5467  C CD2 . LEU B 1 387 ? 164.921 128.929 148.016 1.00 61.75  ? 440 LEU B CD2 1 
ATOM   5468  N N   . VAL B 1 388 ? 161.917 126.942 145.330 1.00 57.34  ? 441 VAL B N   1 
ATOM   5469  C CA  . VAL B 1 388 ? 162.331 125.827 144.484 1.00 57.36  ? 441 VAL B CA  1 
ATOM   5470  C C   . VAL B 1 388 ? 161.467 125.757 143.226 1.00 61.97  ? 441 VAL B C   1 
ATOM   5471  O O   . VAL B 1 388 ? 161.970 125.473 142.129 1.00 63.93  ? 441 VAL B O   1 
ATOM   5472  C CB  . VAL B 1 388 ? 162.318 124.507 145.278 1.00 49.16  ? 441 VAL B CB  1 
ATOM   5473  C CG1 . VAL B 1 388 ? 160.927 124.178 145.788 1.00 53.13  ? 441 VAL B CG1 1 
ATOM   5474  C CG2 . VAL B 1 388 ? 162.863 123.371 144.430 1.00 54.52  ? 441 VAL B CG2 1 
ATOM   5475  N N   . TYR B 1 389 ? 160.168 126.049 143.351 1.00 58.93  ? 442 TYR B N   1 
ATOM   5476  C CA  . TYR B 1 389 ? 159.283 126.012 142.191 1.00 52.34  ? 442 TYR B CA  1 
ATOM   5477  C C   . TYR B 1 389 ? 159.722 127.017 141.135 1.00 53.07  ? 442 TYR B C   1 
ATOM   5478  O O   . TYR B 1 389 ? 159.872 126.672 139.957 1.00 59.08  ? 442 TYR B O   1 
ATOM   5479  C CB  . TYR B 1 389 ? 157.843 126.281 142.632 1.00 51.60  ? 442 TYR B CB  1 
ATOM   5480  C CG  . TYR B 1 389 ? 156.832 126.329 141.507 1.00 50.75  ? 442 TYR B CG  1 
ATOM   5481  C CD1 . TYR B 1 389 ? 156.532 127.522 140.866 1.00 52.90  ? 442 TYR B CD1 1 
ATOM   5482  C CD2 . TYR B 1 389 ? 156.162 125.185 141.102 1.00 50.85  ? 442 TYR B CD2 1 
ATOM   5483  C CE1 . TYR B 1 389 ? 155.607 127.572 139.846 1.00 52.74  ? 442 TYR B CE1 1 
ATOM   5484  C CE2 . TYR B 1 389 ? 155.233 125.226 140.083 1.00 54.39  ? 442 TYR B CE2 1 
ATOM   5485  C CZ  . TYR B 1 389 ? 154.961 126.423 139.459 1.00 52.54  ? 442 TYR B CZ  1 
ATOM   5486  O OH  . TYR B 1 389 ? 154.036 126.472 138.443 1.00 52.39  ? 442 TYR B OH  1 
ATOM   5487  N N   . TRP B 1 390 ? 159.934 128.270 141.538 1.00 53.73  ? 443 TRP B N   1 
ATOM   5488  C CA  . TRP B 1 390 ? 160.308 129.292 140.569 1.00 56.32  ? 443 TRP B CA  1 
ATOM   5489  C C   . TRP B 1 390 ? 161.739 129.115 140.078 1.00 62.64  ? 443 TRP B C   1 
ATOM   5490  O O   . TRP B 1 390 ? 162.046 129.486 138.941 1.00 71.38  ? 443 TRP B O   1 
ATOM   5491  C CB  . TRP B 1 390 ? 160.105 130.685 141.165 1.00 58.03  ? 443 TRP B CB  1 
ATOM   5492  C CG  . TRP B 1 390 ? 158.659 131.024 141.371 1.00 61.07  ? 443 TRP B CG  1 
ATOM   5493  C CD1 . TRP B 1 390 ? 158.017 131.191 142.561 1.00 64.01  ? 443 TRP B CD1 1 
ATOM   5494  C CD2 . TRP B 1 390 ? 157.671 131.220 140.353 1.00 56.51  ? 443 TRP B CD2 1 
ATOM   5495  N NE1 . TRP B 1 390 ? 156.693 131.485 142.349 1.00 60.87  ? 443 TRP B NE1 1 
ATOM   5496  C CE2 . TRP B 1 390 ? 156.455 131.509 141.001 1.00 55.40  ? 443 TRP B CE2 1 
ATOM   5497  C CE3 . TRP B 1 390 ? 157.698 131.183 138.956 1.00 55.20  ? 443 TRP B CE3 1 
ATOM   5498  C CZ2 . TRP B 1 390 ? 155.278 131.760 140.302 1.00 49.43  ? 443 TRP B CZ2 1 
ATOM   5499  C CZ3 . TRP B 1 390 ? 156.529 131.432 138.264 1.00 55.16  ? 443 TRP B CZ3 1 
ATOM   5500  C CH2 . TRP B 1 390 ? 155.336 131.716 138.937 1.00 50.46  ? 443 TRP B CH2 1 
ATOM   5501  N N   . LEU B 1 391 ? 162.629 128.557 140.904 1.00 59.50  ? 444 LEU B N   1 
ATOM   5502  C CA  . LEU B 1 391 ? 163.983 128.288 140.440 1.00 66.11  ? 444 LEU B CA  1 
ATOM   5503  C C   . LEU B 1 391 ? 164.041 127.125 139.462 1.00 71.54  ? 444 LEU B C   1 
ATOM   5504  O O   . LEU B 1 391 ? 164.992 127.040 138.679 1.00 75.38  ? 444 LEU B O   1 
ATOM   5505  C CB  . LEU B 1 391 ? 164.910 128.011 141.624 1.00 73.70  ? 444 LEU B CB  1 
ATOM   5506  C CG  . LEU B 1 391 ? 165.376 129.217 142.440 1.00 82.07  ? 444 LEU B CG  1 
ATOM   5507  C CD1 . LEU B 1 391 ? 166.327 128.775 143.540 1.00 79.76  ? 444 LEU B CD1 1 
ATOM   5508  C CD2 . LEU B 1 391 ? 166.033 130.253 141.543 1.00 79.47  ? 444 LEU B CD2 1 
ATOM   5509  N N   . TYR B 1 392 ? 163.055 126.225 139.487 1.00 69.99  ? 445 TYR B N   1 
ATOM   5510  C CA  . TYR B 1 392 ? 163.080 125.113 138.544 1.00 66.61  ? 445 TYR B CA  1 
ATOM   5511  C C   . TYR B 1 392 ? 162.471 125.498 137.198 1.00 68.30  ? 445 TYR B C   1 
ATOM   5512  O O   . TYR B 1 392 ? 163.041 125.196 136.144 1.00 67.63  ? 445 TYR B O   1 
ATOM   5513  C CB  . TYR B 1 392 ? 162.352 123.903 139.130 1.00 60.22  ? 445 TYR B CB  1 
ATOM   5514  C CG  . TYR B 1 392 ? 162.312 122.722 138.189 1.00 67.42  ? 445 TYR B CG  1 
ATOM   5515  C CD1 . TYR B 1 392 ? 163.414 121.892 138.039 1.00 76.86  ? 445 TYR B CD1 1 
ATOM   5516  C CD2 . TYR B 1 392 ? 161.174 122.440 137.446 1.00 67.49  ? 445 TYR B CD2 1 
ATOM   5517  C CE1 . TYR B 1 392 ? 163.383 120.813 137.176 1.00 79.19  ? 445 TYR B CE1 1 
ATOM   5518  C CE2 . TYR B 1 392 ? 161.135 121.364 136.582 1.00 72.55  ? 445 TYR B CE2 1 
ATOM   5519  C CZ  . TYR B 1 392 ? 162.240 120.554 136.451 1.00 78.29  ? 445 TYR B CZ  1 
ATOM   5520  O OH  . TYR B 1 392 ? 162.202 119.480 135.591 1.00 83.15  ? 445 TYR B OH  1 
ATOM   5521  N N   . TYR B 1 393 ? 161.324 126.172 137.211 1.00 66.65  ? 446 TYR B N   1 
ATOM   5522  C CA  . TYR B 1 393 ? 160.567 126.434 135.993 1.00 59.85  ? 446 TYR B CA  1 
ATOM   5523  C C   . TYR B 1 393 ? 160.956 127.732 135.298 1.00 62.26  ? 446 TYR B C   1 
ATOM   5524  O O   . TYR B 1 393 ? 160.313 128.099 134.309 1.00 65.04  ? 446 TYR B O   1 
ATOM   5525  C CB  . TYR B 1 393 ? 159.067 126.450 136.297 1.00 52.45  ? 446 TYR B CB  1 
ATOM   5526  C CG  . TYR B 1 393 ? 158.503 125.087 136.612 1.00 54.00  ? 446 TYR B CG  1 
ATOM   5527  C CD1 . TYR B 1 393 ? 158.122 124.223 135.599 1.00 55.46  ? 446 TYR B CD1 1 
ATOM   5528  C CD2 . TYR B 1 393 ? 158.357 124.662 137.923 1.00 60.26  ? 446 TYR B CD2 1 
ATOM   5529  C CE1 . TYR B 1 393 ? 157.610 122.973 135.882 1.00 60.70  ? 446 TYR B CE1 1 
ATOM   5530  C CE2 . TYR B 1 393 ? 157.844 123.415 138.216 1.00 58.39  ? 446 TYR B CE2 1 
ATOM   5531  C CZ  . TYR B 1 393 ? 157.471 122.576 137.192 1.00 58.69  ? 446 TYR B CZ  1 
ATOM   5532  O OH  . TYR B 1 393 ? 156.962 121.332 137.479 1.00 60.15  ? 446 TYR B OH  1 
ATOM   5533  N N   . VAL B 1 394 ? 161.974 128.435 135.779 1.00 65.63  ? 447 VAL B N   1 
ATOM   5534  C CA  . VAL B 1 394 ? 162.442 129.635 135.096 1.00 71.69  ? 447 VAL B CA  1 
ATOM   5535  C C   . VAL B 1 394 ? 163.840 129.404 134.539 1.00 79.82  ? 447 VAL B C   1 
ATOM   5536  O O   . VAL B 1 394 ? 164.103 128.383 133.902 1.00 76.49  ? 447 VAL B O   1 
ATOM   5537  C CB  . VAL B 1 394 ? 162.419 130.859 136.024 1.00 65.33  ? 447 VAL B CB  1 
ATOM   5538  C CG1 . VAL B 1 394 ? 163.093 132.044 135.352 1.00 71.00  ? 447 VAL B CG1 1 
ATOM   5539  C CG2 . VAL B 1 394 ? 160.992 131.207 136.401 1.00 58.60  ? 447 VAL B CG2 1 
ATOM   5540  N N   . ASN C 1 58  ? 154.991 116.707 68.482  1.00 135.64 ? 4   ASN C N   1 
ATOM   5541  C CA  . ASN C 1 58  ? 154.948 115.298 68.856  1.00 136.32 ? 4   ASN C CA  1 
ATOM   5542  C C   . ASN C 1 58  ? 155.754 115.036 70.124  1.00 143.20 ? 4   ASN C C   1 
ATOM   5543  O O   . ASN C 1 58  ? 155.417 114.153 70.914  1.00 141.36 ? 4   ASN C O   1 
ATOM   5544  C CB  . ASN C 1 58  ? 155.469 114.426 67.712  1.00 133.69 ? 4   ASN C CB  1 
ATOM   5545  C CG  . ASN C 1 58  ? 155.515 112.954 68.074  1.00 139.98 ? 4   ASN C CG  1 
ATOM   5546  O OD1 . ASN C 1 58  ? 154.519 112.242 67.950  1.00 138.92 ? 4   ASN C OD1 1 
ATOM   5547  N ND2 . ASN C 1 58  ? 156.675 112.491 68.525  1.00 143.25 ? 4   ASN C ND2 1 
ATOM   5548  N N   . ASP C 1 59  ? 156.820 115.811 70.314  1.00 147.10 ? 5   ASP C N   1 
ATOM   5549  C CA  . ASP C 1 59  ? 157.708 115.610 71.444  1.00 146.06 ? 5   ASP C CA  1 
ATOM   5550  C C   . ASP C 1 59  ? 157.016 115.986 72.752  1.00 143.91 ? 5   ASP C C   1 
ATOM   5551  O O   . ASP C 1 59  ? 156.087 116.797 72.766  1.00 139.99 ? 5   ASP C O   1 
ATOM   5552  C CB  . ASP C 1 59  ? 158.980 116.436 71.271  1.00 145.56 ? 5   ASP C CB  1 
ATOM   5553  C CG  . ASP C 1 59  ? 159.698 116.135 69.970  1.00 150.38 ? 5   ASP C CG  1 
ATOM   5554  O OD1 . ASP C 1 59  ? 159.122 115.421 69.123  1.00 149.90 ? 5   ASP C OD1 1 
ATOM   5555  O OD2 . ASP C 1 59  ? 160.841 116.609 69.797  1.00 153.81 ? 5   ASP C OD2 1 
ATOM   5556  N N   . PRO C 1 60  ? 157.446 115.389 73.869  1.00 145.66 ? 6   PRO C N   1 
ATOM   5557  C CA  . PRO C 1 60  ? 156.885 115.795 75.170  1.00 143.74 ? 6   PRO C CA  1 
ATOM   5558  C C   . PRO C 1 60  ? 157.078 117.270 75.471  1.00 140.47 ? 6   PRO C C   1 
ATOM   5559  O O   . PRO C 1 60  ? 156.211 117.890 76.099  1.00 135.36 ? 6   PRO C O   1 
ATOM   5560  C CB  . PRO C 1 60  ? 157.641 114.902 76.165  1.00 138.44 ? 6   PRO C CB  1 
ATOM   5561  C CG  . PRO C 1 60  ? 158.053 113.712 75.363  1.00 134.27 ? 6   PRO C CG  1 
ATOM   5562  C CD  . PRO C 1 60  ? 158.360 114.241 73.993  1.00 139.80 ? 6   PRO C CD  1 
ATOM   5563  N N   . GLY C 1 61  ? 158.196 117.854 75.038  1.00 141.55 ? 7   GLY C N   1 
ATOM   5564  C CA  . GLY C 1 61  ? 158.407 119.280 75.210  1.00 138.51 ? 7   GLY C CA  1 
ATOM   5565  C C   . GLY C 1 61  ? 157.566 120.149 74.299  1.00 139.21 ? 7   GLY C C   1 
ATOM   5566  O O   . GLY C 1 61  ? 157.494 121.363 74.522  1.00 137.84 ? 7   GLY C O   1 
ATOM   5567  N N   . ASN C 1 62  ? 156.936 119.561 73.285  1.00 139.32 ? 8   ASN C N   1 
ATOM   5568  C CA  . ASN C 1 62  ? 156.021 120.279 72.402  1.00 133.93 ? 8   ASN C CA  1 
ATOM   5569  C C   . ASN C 1 62  ? 154.675 120.369 73.109  1.00 129.18 ? 8   ASN C C   1 
ATOM   5570  O O   . ASN C 1 62  ? 153.889 119.420 73.102  1.00 128.42 ? 8   ASN C O   1 
ATOM   5571  C CB  . ASN C 1 62  ? 155.908 119.565 71.060  1.00 131.82 ? 8   ASN C CB  1 
ATOM   5572  C CG  . ASN C 1 62  ? 155.104 120.347 70.038  1.00 132.38 ? 8   ASN C CG  1 
ATOM   5573  O OD1 . ASN C 1 62  ? 154.448 121.337 70.363  1.00 131.81 ? 8   ASN C OD1 1 
ATOM   5574  N ND2 . ASN C 1 62  ? 155.149 119.898 68.790  1.00 139.84 ? 8   ASN C ND2 1 
ATOM   5575  N N   . MET C 1 63  ? 154.407 121.521 73.727  1.00 122.75 ? 9   MET C N   1 
ATOM   5576  C CA  . MET C 1 63  ? 153.185 121.670 74.510  1.00 114.58 ? 9   MET C CA  1 
ATOM   5577  C C   . MET C 1 63  ? 151.949 121.750 73.626  1.00 113.58 ? 9   MET C C   1 
ATOM   5578  O O   . MET C 1 63  ? 150.851 121.398 74.069  1.00 112.12 ? 9   MET C O   1 
ATOM   5579  C CB  . MET C 1 63  ? 153.283 122.906 75.403  1.00 108.46 ? 9   MET C CB  1 
ATOM   5580  C CG  . MET C 1 63  ? 154.370 122.813 76.460  1.00 111.69 ? 9   MET C CG  1 
ATOM   5581  S SD  . MET C 1 63  ? 154.494 124.297 77.473  1.00 113.75 ? 9   MET C SD  1 
ATOM   5582  C CE  . MET C 1 63  ? 152.827 124.407 78.112  1.00 103.61 ? 9   MET C CE  1 
ATOM   5583  N N   . SER C 1 64  ? 152.101 122.213 72.383  1.00 118.19 ? 10  SER C N   1 
ATOM   5584  C CA  . SER C 1 64  ? 150.961 122.276 71.474  1.00 116.33 ? 10  SER C CA  1 
ATOM   5585  C C   . SER C 1 64  ? 150.418 120.885 71.171  1.00 114.60 ? 10  SER C C   1 
ATOM   5586  O O   . SER C 1 64  ? 149.200 120.689 71.096  1.00 112.58 ? 10  SER C O   1 
ATOM   5587  C CB  . SER C 1 64  ? 151.358 122.990 70.184  1.00 119.63 ? 10  SER C CB  1 
ATOM   5588  O OG  . SER C 1 64  ? 152.485 122.371 69.593  1.00 128.89 ? 10  SER C OG  1 
ATOM   5589  N N   . PHE C 1 65  ? 151.307 119.907 70.983  1.00 117.16 ? 11  PHE C N   1 
ATOM   5590  C CA  . PHE C 1 65  ? 150.866 118.537 70.743  1.00 116.55 ? 11  PHE C CA  1 
ATOM   5591  C C   . PHE C 1 65  ? 150.111 117.979 71.946  1.00 110.83 ? 11  PHE C C   1 
ATOM   5592  O O   . PHE C 1 65  ? 149.085 117.305 71.790  1.00 108.65 ? 11  PHE C O   1 
ATOM   5593  C CB  . PHE C 1 65  ? 152.070 117.660 70.398  1.00 119.85 ? 11  PHE C CB  1 
ATOM   5594  C CG  . PHE C 1 65  ? 151.755 116.197 70.318  1.00 121.18 ? 11  PHE C CG  1 
ATOM   5595  C CD1 . PHE C 1 65  ? 150.947 115.701 69.309  1.00 121.58 ? 11  PHE C CD1 1 
ATOM   5596  C CD2 . PHE C 1 65  ? 152.280 115.313 71.243  1.00 120.13 ? 11  PHE C CD2 1 
ATOM   5597  C CE1 . PHE C 1 65  ? 150.660 114.353 69.231  1.00 119.29 ? 11  PHE C CE1 1 
ATOM   5598  C CE2 . PHE C 1 65  ? 151.999 113.965 71.169  1.00 117.38 ? 11  PHE C CE2 1 
ATOM   5599  C CZ  . PHE C 1 65  ? 151.188 113.484 70.163  1.00 116.88 ? 11  PHE C CZ  1 
ATOM   5600  N N   . VAL C 1 66  ? 150.605 118.253 73.155  1.00 108.24 ? 12  VAL C N   1 
ATOM   5601  C CA  . VAL C 1 66  ? 149.921 117.803 74.363  1.00 102.44 ? 12  VAL C CA  1 
ATOM   5602  C C   . VAL C 1 66  ? 148.552 118.461 74.478  1.00 98.58  ? 12  VAL C C   1 
ATOM   5603  O O   . VAL C 1 66  ? 147.563 117.814 74.847  1.00 98.15  ? 12  VAL C O   1 
ATOM   5604  C CB  . VAL C 1 66  ? 150.790 118.082 75.603  1.00 99.25  ? 12  VAL C CB  1 
ATOM   5605  C CG1 . VAL C 1 66  ? 150.097 117.588 76.861  1.00 94.70  ? 12  VAL C CG1 1 
ATOM   5606  C CG2 . VAL C 1 66  ? 152.153 117.430 75.448  1.00 103.23 ? 12  VAL C CG2 1 
ATOM   5607  N N   . LYS C 1 67  ? 148.475 119.760 74.180  1.00 98.29  ? 13  LYS C N   1 
ATOM   5608  C CA  . LYS C 1 67  ? 147.192 120.452 74.223  1.00 95.78  ? 13  LYS C CA  1 
ATOM   5609  C C   . LYS C 1 67  ? 146.220 119.873 73.206  1.00 96.11  ? 13  LYS C C   1 
ATOM   5610  O O   . LYS C 1 67  ? 145.030 119.710 73.496  1.00 94.03  ? 13  LYS C O   1 
ATOM   5611  C CB  . LYS C 1 67  ? 147.386 121.948 73.978  1.00 99.76  ? 13  LYS C CB  1 
ATOM   5612  C CG  . LYS C 1 67  ? 146.077 122.704 73.859  1.00 97.30  ? 13  LYS C CG  1 
ATOM   5613  C CD  . LYS C 1 67  ? 146.280 124.137 73.421  1.00 99.69  ? 13  LYS C CD  1 
ATOM   5614  C CE  . LYS C 1 67  ? 144.941 124.812 73.181  1.00 102.96 ? 13  LYS C CE  1 
ATOM   5615  N NZ  . LYS C 1 67  ? 145.099 126.201 72.683  1.00 107.77 ? 13  LYS C NZ  1 
ATOM   5616  N N   . GLU C 1 68  ? 146.710 119.564 72.003  1.00 100.18 ? 14  GLU C N   1 
ATOM   5617  C CA  . GLU C 1 68  ? 145.860 118.937 70.998  1.00 99.76  ? 14  GLU C CA  1 
ATOM   5618  C C   . GLU C 1 68  ? 145.352 117.587 71.478  1.00 96.85  ? 14  GLU C C   1 
ATOM   5619  O O   . GLU C 1 68  ? 144.173 117.262 71.304  1.00 98.94  ? 14  GLU C O   1 
ATOM   5620  C CB  . GLU C 1 68  ? 146.622 118.776 69.684  1.00 106.57 ? 14  GLU C CB  1 
ATOM   5621  C CG  . GLU C 1 68  ? 146.845 120.065 68.921  1.00 122.26 ? 14  GLU C CG  1 
ATOM   5622  C CD  . GLU C 1 68  ? 147.496 119.829 67.573  1.00 134.00 ? 14  GLU C CD  1 
ATOM   5623  O OE1 . GLU C 1 68  ? 147.936 118.688 67.317  1.00 132.63 ? 14  GLU C OE1 1 
ATOM   5624  O OE2 . GLU C 1 68  ? 147.566 120.782 66.769  1.00 136.04 ? 14  GLU C OE2 1 
ATOM   5625  N N   . THR C 1 69  ? 146.229 116.788 72.087  1.00 96.32  ? 15  THR C N   1 
ATOM   5626  C CA  . THR C 1 69  ? 145.816 115.480 72.584  1.00 93.32  ? 15  THR C CA  1 
ATOM   5627  C C   . THR C 1 69  ? 144.750 115.616 73.666  1.00 88.62  ? 15  THR C C   1 
ATOM   5628  O O   . THR C 1 69  ? 143.745 114.897 73.659  1.00 87.81  ? 15  THR C O   1 
ATOM   5629  C CB  . THR C 1 69  ? 147.026 114.714 73.115  1.00 93.96  ? 15  THR C CB  1 
ATOM   5630  O OG1 . THR C 1 69  ? 148.066 114.721 72.130  1.00 100.38 ? 15  THR C OG1 1 
ATOM   5631  C CG2 . THR C 1 69  ? 146.646 113.278 73.424  1.00 88.04  ? 15  THR C CG2 1 
ATOM   5632  N N   . VAL C 1 70  ? 144.947 116.551 74.598  1.00 87.26  ? 16  VAL C N   1 
ATOM   5633  C CA  . VAL C 1 70  ? 143.984 116.724 75.682  1.00 81.35  ? 16  VAL C CA  1 
ATOM   5634  C C   . VAL C 1 70  ? 142.647 117.222 75.145  1.00 82.30  ? 16  VAL C C   1 
ATOM   5635  O O   . VAL C 1 70  ? 141.582 116.744 75.554  1.00 80.05  ? 16  VAL C O   1 
ATOM   5636  C CB  . VAL C 1 70  ? 144.552 117.664 76.760  1.00 77.75  ? 16  VAL C CB  1 
ATOM   5637  C CG1 . VAL C 1 70  ? 143.508 117.933 77.826  1.00 71.64  ? 16  VAL C CG1 1 
ATOM   5638  C CG2 . VAL C 1 70  ? 145.792 117.054 77.386  1.00 74.63  ? 16  VAL C CG2 1 
ATOM   5639  N N   . ASP C 1 71  ? 142.676 118.190 74.224  1.00 86.65  ? 17  ASP C N   1 
ATOM   5640  C CA  . ASP C 1 71  ? 141.434 118.700 73.652  1.00 89.26  ? 17  ASP C CA  1 
ATOM   5641  C C   . ASP C 1 71  ? 140.706 117.620 72.862  1.00 88.61  ? 17  ASP C C   1 
ATOM   5642  O O   . ASP C 1 71  ? 139.472 117.541 72.895  1.00 90.01  ? 17  ASP C O   1 
ATOM   5643  C CB  . ASP C 1 71  ? 141.720 119.917 72.773  1.00 93.96  ? 17  ASP C CB  1 
ATOM   5644  C CG  . ASP C 1 71  ? 142.251 121.096 73.566  1.00 100.40 ? 17  ASP C CG  1 
ATOM   5645  O OD1 . ASP C 1 71  ? 142.431 120.956 74.794  1.00 99.40  ? 17  ASP C OD1 1 
ATOM   5646  O OD2 . ASP C 1 71  ? 142.488 122.164 72.963  1.00 105.20 ? 17  ASP C OD2 1 
ATOM   5647  N N   . LYS C 1 72  ? 141.452 116.781 72.141  1.00 86.89  ? 18  LYS C N   1 
ATOM   5648  C CA  . LYS C 1 72  ? 140.841 115.656 71.442  1.00 85.50  ? 18  LYS C CA  1 
ATOM   5649  C C   . LYS C 1 72  ? 140.216 114.677 72.426  1.00 85.59  ? 18  LYS C C   1 
ATOM   5650  O O   . LYS C 1 72  ? 139.148 114.113 72.159  1.00 87.30  ? 18  LYS C O   1 
ATOM   5651  C CB  . LYS C 1 72  ? 141.886 114.958 70.572  1.00 89.62  ? 18  LYS C CB  1 
ATOM   5652  C CG  . LYS C 1 72  ? 141.346 113.820 69.729  1.00 90.48  ? 18  LYS C CG  1 
ATOM   5653  C CD  . LYS C 1 72  ? 142.457 113.195 68.904  1.00 88.71  ? 18  LYS C CD  1 
ATOM   5654  C CE  . LYS C 1 72  ? 141.935 112.078 68.020  1.00 91.31  ? 18  LYS C CE  1 
ATOM   5655  N NZ  . LYS C 1 72  ? 143.025 111.488 67.193  1.00 92.84  ? 18  LYS C NZ  1 
ATOM   5656  N N   . LEU C 1 73  ? 140.874 114.454 73.566  1.00 84.97  ? 19  LEU C N   1 
ATOM   5657  C CA  . LEU C 1 73  ? 140.297 113.600 74.600  1.00 79.42  ? 19  LEU C CA  1 
ATOM   5658  C C   . LEU C 1 73  ? 138.995 114.182 75.131  1.00 80.40  ? 19  LEU C C   1 
ATOM   5659  O O   . LEU C 1 73  ? 138.026 113.450 75.362  1.00 83.95  ? 19  LEU C O   1 
ATOM   5660  C CB  . LEU C 1 73  ? 141.292 113.406 75.743  1.00 73.95  ? 19  LEU C CB  1 
ATOM   5661  C CG  . LEU C 1 73  ? 142.504 112.517 75.479  1.00 76.29  ? 19  LEU C CG  1 
ATOM   5662  C CD1 . LEU C 1 73  ? 143.356 112.403 76.733  1.00 72.75  ? 19  LEU C CD1 1 
ATOM   5663  C CD2 . LEU C 1 73  ? 142.055 111.148 75.005  1.00 73.34  ? 19  LEU C CD2 1 
ATOM   5664  N N   . LEU C 1 74  ? 138.954 115.496 75.336  1.00 81.36  ? 20  LEU C N   1 
ATOM   5665  C CA  . LEU C 1 74  ? 137.761 116.144 75.864  1.00 79.10  ? 20  LEU C CA  1 
ATOM   5666  C C   . LEU C 1 74  ? 136.737 116.489 74.790  1.00 79.53  ? 20  LEU C C   1 
ATOM   5667  O O   . LEU C 1 74  ? 135.667 117.005 75.127  1.00 78.65  ? 20  LEU C O   1 
ATOM   5668  C CB  . LEU C 1 74  ? 138.146 117.407 76.636  1.00 76.03  ? 20  LEU C CB  1 
ATOM   5669  C CG  . LEU C 1 74  ? 138.944 117.153 77.914  1.00 74.33  ? 20  LEU C CG  1 
ATOM   5670  C CD1 . LEU C 1 74  ? 139.125 118.437 78.702  1.00 75.64  ? 20  LEU C CD1 1 
ATOM   5671  C CD2 . LEU C 1 74  ? 138.253 116.100 78.756  1.00 67.73  ? 20  LEU C CD2 1 
ATOM   5672  N N   . LYS C 1 75  ? 137.029 116.226 73.519  1.00 82.59  ? 21  LYS C N   1 
ATOM   5673  C CA  . LYS C 1 75  ? 136.060 116.462 72.456  1.00 85.83  ? 21  LYS C CA  1 
ATOM   5674  C C   . LYS C 1 75  ? 135.035 115.336 72.450  1.00 82.69  ? 21  LYS C C   1 
ATOM   5675  O O   . LYS C 1 75  ? 135.397 114.160 72.336  1.00 79.88  ? 21  LYS C O   1 
ATOM   5676  C CB  . LYS C 1 75  ? 136.755 116.559 71.101  1.00 90.08  ? 21  LYS C CB  1 
ATOM   5677  C CG  . LYS C 1 75  ? 135.793 116.763 69.942  1.00 93.63  ? 21  LYS C CG  1 
ATOM   5678  C CD  . LYS C 1 75  ? 136.503 116.676 68.604  1.00 105.97 ? 21  LYS C CD  1 
ATOM   5679  C CE  . LYS C 1 75  ? 135.524 116.834 67.452  1.00 116.16 ? 21  LYS C CE  1 
ATOM   5680  N NZ  . LYS C 1 75  ? 136.198 116.702 66.131  1.00 123.28 ? 21  LYS C NZ  1 
ATOM   5681  N N   . GLY C 1 76  ? 133.759 115.693 72.575  1.00 82.46  ? 22  GLY C N   1 
ATOM   5682  C CA  . GLY C 1 76  ? 132.699 114.711 72.618  1.00 81.88  ? 22  GLY C CA  1 
ATOM   5683  C C   . GLY C 1 76  ? 132.560 113.984 73.935  1.00 79.66  ? 22  GLY C C   1 
ATOM   5684  O O   . GLY C 1 76  ? 131.696 113.104 74.049  1.00 76.71  ? 22  GLY C O   1 
ATOM   5685  N N   . TYR C 1 77  ? 133.378 114.318 74.928  1.00 79.04  ? 23  TYR C N   1 
ATOM   5686  C CA  . TYR C 1 77  ? 133.285 113.678 76.231  1.00 73.56  ? 23  TYR C CA  1 
ATOM   5687  C C   . TYR C 1 77  ? 131.980 114.066 76.912  1.00 73.02  ? 23  TYR C C   1 
ATOM   5688  O O   . TYR C 1 77  ? 131.572 115.230 76.893  1.00 69.85  ? 23  TYR C O   1 
ATOM   5689  C CB  . TYR C 1 77  ? 134.479 114.078 77.097  1.00 72.90  ? 23  TYR C CB  1 
ATOM   5690  C CG  . TYR C 1 77  ? 134.653 113.241 78.340  1.00 69.05  ? 23  TYR C CG  1 
ATOM   5691  C CD1 . TYR C 1 77  ? 135.351 112.044 78.299  1.00 67.69  ? 23  TYR C CD1 1 
ATOM   5692  C CD2 . TYR C 1 77  ? 134.128 113.651 79.556  1.00 66.58  ? 23  TYR C CD2 1 
ATOM   5693  C CE1 . TYR C 1 77  ? 135.517 111.276 79.431  1.00 65.77  ? 23  TYR C CE1 1 
ATOM   5694  C CE2 . TYR C 1 77  ? 134.290 112.889 80.694  1.00 65.53  ? 23  TYR C CE2 1 
ATOM   5695  C CZ  . TYR C 1 77  ? 134.985 111.703 80.626  1.00 65.30  ? 23  TYR C CZ  1 
ATOM   5696  O OH  . TYR C 1 77  ? 135.149 110.939 81.758  1.00 66.67  ? 23  TYR C OH  1 
ATOM   5697  N N   . ASP C 1 78  ? 131.322 113.081 77.515  1.00 73.80  ? 24  ASP C N   1 
ATOM   5698  C CA  . ASP C 1 78  ? 130.019 113.269 78.147  1.00 72.67  ? 24  ASP C CA  1 
ATOM   5699  C C   . ASP C 1 78  ? 130.181 113.049 79.648  1.00 69.42  ? 24  ASP C C   1 
ATOM   5700  O O   . ASP C 1 78  ? 130.309 111.910 80.106  1.00 70.82  ? 24  ASP C O   1 
ATOM   5701  C CB  . ASP C 1 78  ? 128.985 112.318 77.550  1.00 70.62  ? 24  ASP C CB  1 
ATOM   5702  C CG  . ASP C 1 78  ? 127.568 112.839 77.681  1.00 74.50  ? 24  ASP C CG  1 
ATOM   5703  O OD1 . ASP C 1 78  ? 127.391 113.983 78.148  1.00 76.70  ? 24  ASP C OD1 1 
ATOM   5704  O OD2 . ASP C 1 78  ? 126.629 112.103 77.310  1.00 75.96  ? 24  ASP C OD2 1 
ATOM   5705  N N   . ILE C 1 79  ? 130.176 114.143 80.414  1.00 64.39  ? 25  ILE C N   1 
ATOM   5706  C CA  . ILE C 1 79  ? 130.292 114.045 81.864  1.00 62.66  ? 25  ILE C CA  1 
ATOM   5707  C C   . ILE C 1 79  ? 129.056 113.444 82.510  1.00 67.69  ? 25  ILE C C   1 
ATOM   5708  O O   . ILE C 1 79  ? 129.096 113.090 83.693  1.00 73.42  ? 25  ILE C O   1 
ATOM   5709  C CB  . ILE C 1 79  ? 130.573 115.426 82.487  1.00 60.51  ? 25  ILE C CB  1 
ATOM   5710  C CG1 . ILE C 1 79  ? 129.359 116.344 82.326  1.00 61.84  ? 25  ILE C CG1 1 
ATOM   5711  C CG2 . ILE C 1 79  ? 131.802 116.053 81.853  1.00 60.41  ? 25  ILE C CG2 1 
ATOM   5712  C CD1 . ILE C 1 79  ? 129.523 117.695 82.989  1.00 60.60  ? 25  ILE C CD1 1 
ATOM   5713  N N   . ARG C 1 80  ? 127.959 113.318 81.766  1.00 66.75  ? 26  ARG C N   1 
ATOM   5714  C CA  . ARG C 1 80  ? 126.725 112.766 82.305  1.00 67.40  ? 26  ARG C CA  1 
ATOM   5715  C C   . ARG C 1 80  ? 126.725 111.245 82.359  1.00 66.21  ? 26  ARG C C   1 
ATOM   5716  O O   . ARG C 1 80  ? 125.855 110.668 83.019  1.00 67.70  ? 26  ARG C O   1 
ATOM   5717  C CB  . ARG C 1 80  ? 125.536 113.255 81.477  1.00 63.47  ? 26  ARG C CB  1 
ATOM   5718  C CG  . ARG C 1 80  ? 125.383 114.766 81.468  1.00 69.19  ? 26  ARG C CG  1 
ATOM   5719  C CD  . ARG C 1 80  ? 124.277 115.219 80.533  1.00 73.26  ? 26  ARG C CD  1 
ATOM   5720  N NE  . ARG C 1 80  ? 124.560 114.874 79.146  1.00 75.16  ? 26  ARG C NE  1 
ATOM   5721  C CZ  . ARG C 1 80  ? 123.847 115.294 78.110  1.00 79.68  ? 26  ARG C CZ  1 
ATOM   5722  N NH1 . ARG C 1 80  ? 122.804 116.091 78.268  1.00 77.70  ? 26  ARG C NH1 1 
ATOM   5723  N NH2 . ARG C 1 80  ? 124.192 114.907 76.886  1.00 85.13  ? 26  ARG C NH2 1 
ATOM   5724  N N   . LEU C 1 81  ? 127.669 110.585 81.693  1.00 65.25  ? 27  LEU C N   1 
ATOM   5725  C CA  . LEU C 1 81  ? 127.700 109.132 81.598  1.00 64.70  ? 27  LEU C CA  1 
ATOM   5726  C C   . LEU C 1 81  ? 128.952 108.592 82.272  1.00 66.54  ? 27  LEU C C   1 
ATOM   5727  O O   . LEU C 1 81  ? 130.050 109.115 82.062  1.00 65.07  ? 27  LEU C O   1 
ATOM   5728  C CB  . LEU C 1 81  ? 127.653 108.673 80.140  1.00 60.91  ? 27  LEU C CB  1 
ATOM   5729  C CG  . LEU C 1 81  ? 126.431 109.109 79.335  1.00 61.23  ? 27  LEU C CG  1 
ATOM   5730  C CD1 . LEU C 1 81  ? 126.452 108.469 77.961  1.00 65.64  ? 27  LEU C CD1 1 
ATOM   5731  C CD2 . LEU C 1 81  ? 125.152 108.755 80.073  1.00 67.29  ? 27  LEU C CD2 1 
ATOM   5732  N N   . ARG C 1 82  ? 128.779 107.546 83.075  1.00 65.47  ? 28  ARG C N   1 
ATOM   5733  C CA  . ARG C 1 82  ? 129.902 106.882 83.705  1.00 58.25  ? 28  ARG C CA  1 
ATOM   5734  C C   . ARG C 1 82  ? 130.701 106.098 82.665  1.00 63.16  ? 28  ARG C C   1 
ATOM   5735  O O   . ARG C 1 82  ? 130.182 105.758 81.599  1.00 69.41  ? 28  ARG C O   1 
ATOM   5736  C CB  . ARG C 1 82  ? 129.413 105.947 84.806  1.00 55.29  ? 28  ARG C CB  1 
ATOM   5737  C CG  . ARG C 1 82  ? 128.697 104.719 84.287  1.00 58.33  ? 28  ARG C CG  1 
ATOM   5738  C CD  . ARG C 1 82  ? 128.538 103.682 85.376  1.00 60.06  ? 28  ARG C CD  1 
ATOM   5739  N NE  . ARG C 1 82  ? 128.030 102.422 84.851  1.00 60.73  ? 28  ARG C NE  1 
ATOM   5740  C CZ  . ARG C 1 82  ? 128.790 101.476 84.316  1.00 62.74  ? 28  ARG C CZ  1 
ATOM   5741  N NH1 . ARG C 1 82  ? 130.099 101.624 84.203  1.00 66.32  ? 28  ARG C NH1 1 
ATOM   5742  N NH2 . ARG C 1 82  ? 128.222 100.353 83.886  1.00 63.01  ? 28  ARG C NH2 1 
ATOM   5743  N N   . PRO C 1 83  ? 131.972 105.812 82.947  1.00 60.15  ? 29  PRO C N   1 
ATOM   5744  C CA  . PRO C 1 83  ? 132.774 105.028 82.002  1.00 63.36  ? 29  PRO C CA  1 
ATOM   5745  C C   . PRO C 1 83  ? 132.162 103.657 81.760  1.00 69.96  ? 29  PRO C C   1 
ATOM   5746  O O   . PRO C 1 83  ? 131.665 103.008 82.683  1.00 74.76  ? 29  PRO C O   1 
ATOM   5747  C CB  . PRO C 1 83  ? 134.135 104.919 82.697  1.00 63.00  ? 29  PRO C CB  1 
ATOM   5748  C CG  . PRO C 1 83  ? 134.167 106.051 83.656  1.00 56.49  ? 29  PRO C CG  1 
ATOM   5749  C CD  . PRO C 1 83  ? 132.760 106.235 84.115  1.00 56.86  ? 29  PRO C CD  1 
ATOM   5750  N N   . ASP C 1 84  ? 132.220 103.216 80.503  1.00 69.00  ? 30  ASP C N   1 
ATOM   5751  C CA  . ASP C 1 84  ? 131.630 101.948 80.075  1.00 74.61  ? 30  ASP C CA  1 
ATOM   5752  C C   . ASP C 1 84  ? 130.171 101.850 80.511  1.00 71.57  ? 30  ASP C C   1 
ATOM   5753  O O   . ASP C 1 84  ? 129.751 100.893 81.165  1.00 71.28  ? 30  ASP C O   1 
ATOM   5754  C CB  . ASP C 1 84  ? 132.444 100.763 80.595  1.00 78.20  ? 30  ASP C CB  1 
ATOM   5755  C CG  . ASP C 1 84  ? 133.785 100.633 79.902  1.00 94.13  ? 30  ASP C CG  1 
ATOM   5756  O OD1 . ASP C 1 84  ? 133.845 100.863 78.676  1.00 99.57  ? 30  ASP C OD1 1 
ATOM   5757  O OD2 . ASP C 1 84  ? 134.780 100.308 80.583  1.00 97.67  ? 30  ASP C OD2 1 
ATOM   5758  N N   . PHE C 1 85  ? 129.397 102.870 80.145  1.00 67.16  ? 31  PHE C N   1 
ATOM   5759  C CA  . PHE C 1 85  ? 127.993 102.928 80.527  1.00 65.67  ? 31  PHE C CA  1 
ATOM   5760  C C   . PHE C 1 85  ? 127.235 101.732 79.963  1.00 71.98  ? 31  PHE C C   1 
ATOM   5761  O O   . PHE C 1 85  ? 127.359 101.402 78.781  1.00 78.52  ? 31  PHE C O   1 
ATOM   5762  C CB  . PHE C 1 85  ? 127.372 104.232 80.030  1.00 65.24  ? 31  PHE C CB  1 
ATOM   5763  C CG  . PHE C 1 85  ? 126.030 104.533 80.630  1.00 69.15  ? 31  PHE C CG  1 
ATOM   5764  C CD1 . PHE C 1 85  ? 124.877 103.989 80.093  1.00 72.91  ? 31  PHE C CD1 1 
ATOM   5765  C CD2 . PHE C 1 85  ? 125.922 105.370 81.727  1.00 68.74  ? 31  PHE C CD2 1 
ATOM   5766  C CE1 . PHE C 1 85  ? 123.643 104.266 80.643  1.00 73.41  ? 31  PHE C CE1 1 
ATOM   5767  C CE2 . PHE C 1 85  ? 124.691 105.652 82.281  1.00 67.27  ? 31  PHE C CE2 1 
ATOM   5768  C CZ  . PHE C 1 85  ? 123.550 105.100 81.738  1.00 72.71  ? 31  PHE C CZ  1 
ATOM   5769  N N   . GLY C 1 86  ? 126.447 101.085 80.819  1.00 72.23  ? 32  GLY C N   1 
ATOM   5770  C CA  . GLY C 1 86  ? 125.660 99.938  80.429  1.00 70.20  ? 32  GLY C CA  1 
ATOM   5771  C C   . GLY C 1 86  ? 126.388 98.613  80.464  1.00 68.37  ? 32  GLY C C   1 
ATOM   5772  O O   . GLY C 1 86  ? 125.734 97.565  80.375  1.00 74.67  ? 32  GLY C O   1 
ATOM   5773  N N   . GLY C 1 87  ? 127.712 98.617  80.588  1.00 63.56  ? 33  GLY C N   1 
ATOM   5774  C CA  . GLY C 1 87  ? 128.477 97.396  80.637  1.00 64.90  ? 33  GLY C CA  1 
ATOM   5775  C C   . GLY C 1 87  ? 128.795 96.975  82.056  1.00 71.02  ? 33  GLY C C   1 
ATOM   5776  O O   . GLY C 1 87  ? 128.005 97.178  82.983  1.00 76.11  ? 33  GLY C O   1 
ATOM   5777  N N   . PRO C 1 88  ? 129.963 96.366  82.248  1.00 68.47  ? 34  PRO C N   1 
ATOM   5778  C CA  . PRO C 1 88  ? 130.374 95.992  83.596  1.00 65.94  ? 34  PRO C CA  1 
ATOM   5779  C C   . PRO C 1 88  ? 130.578 97.226  84.451  1.00 68.74  ? 34  PRO C C   1 
ATOM   5780  O O   . PRO C 1 88  ? 130.901 98.313  83.937  1.00 73.22  ? 34  PRO C O   1 
ATOM   5781  C CB  . PRO C 1 88  ? 131.692 95.240  83.368  1.00 59.21  ? 34  PRO C CB  1 
ATOM   5782  C CG  . PRO C 1 88  ? 131.648 94.810  81.939  1.00 62.50  ? 34  PRO C CG  1 
ATOM   5783  C CD  . PRO C 1 88  ? 130.911 95.896  81.227  1.00 65.11  ? 34  PRO C CD  1 
ATOM   5784  N N   . PRO C 1 89  ? 130.387 97.110  85.765  1.00 63.28  ? 35  PRO C N   1 
ATOM   5785  C CA  . PRO C 1 89  ? 130.580 98.272  86.639  1.00 58.33  ? 35  PRO C CA  1 
ATOM   5786  C C   . PRO C 1 89  ? 132.022 98.754  86.621  1.00 61.44  ? 35  PRO C C   1 
ATOM   5787  O O   . PRO C 1 89  ? 132.963 97.970  86.490  1.00 66.79  ? 35  PRO C O   1 
ATOM   5788  C CB  . PRO C 1 89  ? 130.184 97.744  88.023  1.00 58.60  ? 35  PRO C CB  1 
ATOM   5789  C CG  . PRO C 1 89  ? 130.366 96.272  87.931  1.00 61.80  ? 35  PRO C CG  1 
ATOM   5790  C CD  . PRO C 1 89  ? 130.014 95.904  86.523  1.00 64.77  ? 35  PRO C CD  1 
ATOM   5791  N N   . VAL C 1 90  ? 132.185 100.065 86.757  1.00 58.29  ? 36  VAL C N   1 
ATOM   5792  C CA  . VAL C 1 90  ? 133.513 100.666 86.806  1.00 56.18  ? 36  VAL C CA  1 
ATOM   5793  C C   . VAL C 1 90  ? 134.099 100.446 88.194  1.00 59.54  ? 36  VAL C C   1 
ATOM   5794  O O   . VAL C 1 90  ? 133.452 100.730 89.209  1.00 62.56  ? 36  VAL C O   1 
ATOM   5795  C CB  . VAL C 1 90  ? 133.450 102.160 86.447  1.00 50.27  ? 36  VAL C CB  1 
ATOM   5796  C CG1 . VAL C 1 90  ? 132.297 102.838 87.163  1.00 53.55  ? 36  VAL C CG1 1 
ATOM   5797  C CG2 . VAL C 1 90  ? 134.763 102.844 86.783  1.00 49.32  ? 36  VAL C CG2 1 
ATOM   5798  N N   . CYS C 1 91  ? 135.323 99.931  88.242  1.00 59.84  ? 37  CYS C N   1 
ATOM   5799  C CA  . CYS C 1 91  ? 135.971 99.587  89.500  1.00 57.19  ? 37  CYS C CA  1 
ATOM   5800  C C   . CYS C 1 91  ? 136.771 100.783 90.000  1.00 53.58  ? 37  CYS C C   1 
ATOM   5801  O O   . CYS C 1 91  ? 137.677 101.263 89.310  1.00 54.45  ? 37  CYS C O   1 
ATOM   5802  C CB  . CYS C 1 91  ? 136.876 98.369  89.325  1.00 60.60  ? 37  CYS C CB  1 
ATOM   5803  S SG  . CYS C 1 91  ? 136.033 96.894  88.707  1.00 91.55  ? 37  CYS C SG  1 
ATOM   5804  N N   . VAL C 1 92  ? 136.437 101.262 91.194  1.00 50.46  ? 38  VAL C N   1 
ATOM   5805  C CA  . VAL C 1 92  ? 137.095 102.412 91.802  1.00 47.75  ? 38  VAL C CA  1 
ATOM   5806  C C   . VAL C 1 92  ? 137.833 101.935 93.045  1.00 48.60  ? 38  VAL C C   1 
ATOM   5807  O O   . VAL C 1 92  ? 137.222 101.366 93.957  1.00 50.27  ? 38  VAL C O   1 
ATOM   5808  C CB  . VAL C 1 92  ? 136.091 103.520 92.148  1.00 43.80  ? 38  VAL C CB  1 
ATOM   5809  C CG1 . VAL C 1 92  ? 136.814 104.727 92.717  1.00 43.96  ? 38  VAL C CG1 1 
ATOM   5810  C CG2 . VAL C 1 92  ? 135.282 103.905 90.922  1.00 45.46  ? 38  VAL C CG2 1 
ATOM   5811  N N   . GLY C 1 93  ? 139.139 102.171 93.085  1.00 44.81  ? 39  GLY C N   1 
ATOM   5812  C CA  . GLY C 1 93  ? 139.958 101.835 94.239  1.00 44.05  ? 39  GLY C CA  1 
ATOM   5813  C C   . GLY C 1 93  ? 140.291 103.088 95.029  1.00 44.00  ? 39  GLY C C   1 
ATOM   5814  O O   . GLY C 1 93  ? 140.519 104.150 94.457  1.00 47.43  ? 39  GLY C O   1 
ATOM   5815  N N   . MET C 1 94  ? 140.304 102.958 96.352  1.00 42.15  ? 40  MET C N   1 
ATOM   5816  C CA  . MET C 1 94  ? 140.449 104.103 97.239  1.00 39.90  ? 40  MET C CA  1 
ATOM   5817  C C   . MET C 1 94  ? 141.647 103.951 98.161  1.00 38.67  ? 40  MET C C   1 
ATOM   5818  O O   . MET C 1 94  ? 141.914 102.862 98.676  1.00 44.77  ? 40  MET C O   1 
ATOM   5819  C CB  . MET C 1 94  ? 139.197 104.308 98.091  1.00 40.18  ? 40  MET C CB  1 
ATOM   5820  C CG  . MET C 1 94  ? 138.117 105.132 97.432  1.00 39.74  ? 40  MET C CG  1 
ATOM   5821  S SD  . MET C 1 94  ? 136.831 104.123 96.689  1.00 49.34  ? 40  MET C SD  1 
ATOM   5822  C CE  . MET C 1 94  ? 135.686 105.392 96.172  1.00 42.68  ? 40  MET C CE  1 
ATOM   5823  N N   A ASN C 1 95  ? 142.363 105.061 98.359  0.50 38.60  ? 41  ASN C N   1 
ATOM   5824  N N   B ASN C 1 95  ? 142.368 105.045 98.371  0.50 39.32  ? 41  ASN C N   1 
ATOM   5825  C CA  A ASN C 1 95  ? 143.432 105.182 99.339  0.50 40.08  ? 41  ASN C CA  1 
ATOM   5826  C CA  B ASN C 1 95  ? 143.370 105.082 99.422  0.50 40.11  ? 41  ASN C CA  1 
ATOM   5827  C C   A ASN C 1 95  ? 143.167 106.397 100.214 0.50 41.05  ? 41  ASN C C   1 
ATOM   5828  C C   B ASN C 1 95  ? 143.218 106.379 100.201 0.50 40.85  ? 41  ASN C C   1 
ATOM   5829  O O   A ASN C 1 95  ? 142.594 107.392 99.759  0.50 40.88  ? 41  ASN C O   1 
ATOM   5830  O O   B ASN C 1 95  ? 142.734 107.388 99.682  0.50 40.93  ? 41  ASN C O   1 
ATOM   5831  C CB  A ASN C 1 95  ? 144.807 105.340 98.679  0.50 41.10  ? 41  ASN C CB  1 
ATOM   5832  C CB  B ASN C 1 95  ? 144.800 104.922 98.875  0.50 41.93  ? 41  ASN C CB  1 
ATOM   5833  C CG  A ASN C 1 95  ? 144.989 104.436 97.487  0.50 44.39  ? 41  ASN C CG  1 
ATOM   5834  C CG  B ASN C 1 95  ? 145.117 105.893 97.763  0.50 43.68  ? 41  ASN C CG  1 
ATOM   5835  O OD1 A ASN C 1 95  ? 145.018 104.895 96.345  0.50 46.84  ? 41  ASN C OD1 1 
ATOM   5836  O OD1 B ASN C 1 95  ? 144.873 105.614 96.590  0.50 46.95  ? 41  ASN C OD1 1 
ATOM   5837  N ND2 A ASN C 1 95  ? 145.122 103.143 97.742  0.50 45.37  ? 41  ASN C ND2 1 
ATOM   5838  N ND2 B ASN C 1 95  ? 145.687 107.036 98.125  0.50 43.18  ? 41  ASN C ND2 1 
ATOM   5839  N N   . ILE C 1 96  ? 143.601 106.324 101.470 1.00 40.63  ? 42  ILE C N   1 
ATOM   5840  C CA  . ILE C 1 96  ? 143.457 107.433 102.401 1.00 35.20  ? 42  ILE C CA  1 
ATOM   5841  C C   . ILE C 1 96  ? 144.790 107.647 103.098 1.00 40.46  ? 42  ILE C C   1 
ATOM   5842  O O   . ILE C 1 96  ? 145.409 106.689 103.570 1.00 48.71  ? 42  ILE C O   1 
ATOM   5843  C CB  . ILE C 1 96  ? 142.339 107.179 103.431 1.00 36.40  ? 42  ILE C CB  1 
ATOM   5844  C CG1 . ILE C 1 96  ? 141.001 106.949 102.726 1.00 34.66  ? 42  ILE C CG1 1 
ATOM   5845  C CG2 . ILE C 1 96  ? 142.232 108.343 104.396 1.00 39.00  ? 42  ILE C CG2 1 
ATOM   5846  C CD1 . ILE C 1 96  ? 139.852 106.668 103.664 1.00 39.22  ? 42  ILE C CD1 1 
ATOM   5847  N N   . ASP C 1 97  ? 145.231 108.897 103.158 1.00 38.03  ? 43  ASP C N   1 
ATOM   5848  C CA  . ASP C 1 97  ? 146.434 109.282 103.888 1.00 45.40  ? 43  ASP C CA  1 
ATOM   5849  C C   . ASP C 1 97  ? 145.992 110.279 104.951 1.00 46.42  ? 43  ASP C C   1 
ATOM   5850  O O   . ASP C 1 97  ? 145.733 111.445 104.648 1.00 49.86  ? 43  ASP C O   1 
ATOM   5851  C CB  . ASP C 1 97  ? 147.483 109.872 102.952 1.00 51.55  ? 43  ASP C CB  1 
ATOM   5852  C CG  . ASP C 1 97  ? 148.820 110.084 103.630 1.00 62.35  ? 43  ASP C CG  1 
ATOM   5853  O OD1 . ASP C 1 97  ? 148.922 109.835 104.850 1.00 64.91  ? 43  ASP C OD1 1 
ATOM   5854  O OD2 . ASP C 1 97  ? 149.774 110.497 102.940 1.00 68.97  ? 43  ASP C OD2 1 
ATOM   5855  N N   . ILE C 1 98  ? 145.900 109.820 106.194 1.00 45.27  ? 44  ILE C N   1 
ATOM   5856  C CA  . ILE C 1 98  ? 145.318 110.617 107.269 1.00 44.23  ? 44  ILE C CA  1 
ATOM   5857  C C   . ILE C 1 98  ? 146.372 111.598 107.769 1.00 48.91  ? 44  ILE C C   1 
ATOM   5858  O O   . ILE C 1 98  ? 147.385 111.195 108.344 1.00 52.10  ? 44  ILE C O   1 
ATOM   5859  C CB  . ILE C 1 98  ? 144.806 109.725 108.402 1.00 40.07  ? 44  ILE C CB  1 
ATOM   5860  C CG1 . ILE C 1 98  ? 143.598 108.921 107.924 1.00 42.42  ? 44  ILE C CG1 1 
ATOM   5861  C CG2 . ILE C 1 98  ? 144.472 110.556 109.620 1.00 43.40  ? 44  ILE C CG2 1 
ATOM   5862  C CD1 . ILE C 1 98  ? 143.200 107.817 108.858 1.00 47.06  ? 44  ILE C CD1 1 
ATOM   5863  N N   . ALA C 1 99  ? 146.140 112.894 107.542 1.00 49.46  ? 45  ALA C N   1 
ATOM   5864  C CA  . ALA C 1 99  ? 147.097 113.894 107.999 1.00 51.51  ? 45  ALA C CA  1 
ATOM   5865  C C   . ALA C 1 99  ? 147.037 114.063 109.511 1.00 56.15  ? 45  ALA C C   1 
ATOM   5866  O O   . ALA C 1 99  ? 148.079 114.146 110.172 1.00 63.58  ? 45  ALA C O   1 
ATOM   5867  C CB  . ALA C 1 99  ? 146.840 115.227 107.299 1.00 45.83  ? 45  ALA C CB  1 
ATOM   5868  N N   . SER C 1 100 ? 145.833 114.104 110.075 1.00 54.04  ? 46  SER C N   1 
ATOM   5869  C CA  . SER C 1 100 ? 145.660 114.309 111.507 1.00 53.12  ? 46  SER C CA  1 
ATOM   5870  C C   . SER C 1 100 ? 144.204 114.076 111.873 1.00 50.53  ? 46  SER C C   1 
ATOM   5871  O O   . SER C 1 100 ? 143.318 114.084 111.014 1.00 49.71  ? 46  SER C O   1 
ATOM   5872  C CB  . SER C 1 100 ? 146.086 115.719 111.929 1.00 62.85  ? 46  SER C CB  1 
ATOM   5873  O OG  . SER C 1 100 ? 145.250 116.697 111.335 1.00 58.89  ? 46  SER C OG  1 
ATOM   5874  N N   . ILE C 1 101 ? 143.974 113.870 113.165 1.00 57.41  ? 47  ILE C N   1 
ATOM   5875  C CA  . ILE C 1 101 ? 142.642 113.879 113.755 1.00 63.80  ? 47  ILE C CA  1 
ATOM   5876  C C   . ILE C 1 101 ? 142.597 115.072 114.697 1.00 70.62  ? 47  ILE C C   1 
ATOM   5877  O O   . ILE C 1 101 ? 143.263 115.078 115.739 1.00 72.37  ? 47  ILE C O   1 
ATOM   5878  C CB  . ILE C 1 101 ? 142.325 112.566 114.484 1.00 53.83  ? 47  ILE C CB  1 
ATOM   5879  C CG1 . ILE C 1 101 ? 142.213 111.420 113.477 1.00 49.56  ? 47  ILE C CG1 1 
ATOM   5880  C CG2 . ILE C 1 101 ? 141.048 112.701 115.295 1.00 56.63  ? 47  ILE C CG2 1 
ATOM   5881  C CD1 . ILE C 1 101 ? 141.764 110.111 114.080 1.00 45.99  ? 47  ILE C CD1 1 
ATOM   5882  N N   . ASP C 1 102 ? 141.822 116.091 114.323 1.00 68.28  ? 48  ASP C N   1 
ATOM   5883  C CA  . ASP C 1 102 ? 141.883 117.369 115.025 1.00 68.92  ? 48  ASP C CA  1 
ATOM   5884  C C   . ASP C 1 102 ? 141.330 117.256 116.440 1.00 70.00  ? 48  ASP C C   1 
ATOM   5885  O O   . ASP C 1 102 ? 141.948 117.736 117.397 1.00 80.54  ? 48  ASP C O   1 
ATOM   5886  C CB  . ASP C 1 102 ? 141.127 118.434 114.231 1.00 71.69  ? 48  ASP C CB  1 
ATOM   5887  C CG  . ASP C 1 102 ? 141.543 118.477 112.775 1.00 74.96  ? 48  ASP C CG  1 
ATOM   5888  O OD1 . ASP C 1 102 ? 142.291 117.574 112.345 1.00 64.62  ? 48  ASP C OD1 1 
ATOM   5889  O OD2 . ASP C 1 102 ? 141.128 119.413 112.060 1.00 79.46  ? 48  ASP C OD2 1 
ATOM   5890  N N   . MET C 1 103 ? 140.173 116.621 116.595 1.00 67.28  ? 49  MET C N   1 
ATOM   5891  C CA  . MET C 1 103 ? 139.549 116.528 117.906 1.00 71.88  ? 49  MET C CA  1 
ATOM   5892  C C   . MET C 1 103 ? 138.615 115.330 117.939 1.00 69.64  ? 49  MET C C   1 
ATOM   5893  O O   . MET C 1 103 ? 138.122 114.878 116.902 1.00 70.08  ? 49  MET C O   1 
ATOM   5894  C CB  . MET C 1 103 ? 138.777 117.806 118.251 1.00 76.59  ? 49  MET C CB  1 
ATOM   5895  C CG  . MET C 1 103 ? 137.632 118.111 117.301 1.00 78.65  ? 49  MET C CG  1 
ATOM   5896  S SD  . MET C 1 103 ? 136.672 119.551 117.804 1.00 113.72 ? 49  MET C SD  1 
ATOM   5897  C CE  . MET C 1 103 ? 137.931 120.825 117.777 1.00 101.94 ? 49  MET C CE  1 
ATOM   5898  N N   . VAL C 1 104 ? 138.385 114.821 119.146 1.00 68.47  ? 50  VAL C N   1 
ATOM   5899  C CA  . VAL C 1 104 ? 137.419 113.759 119.402 1.00 64.29  ? 50  VAL C CA  1 
ATOM   5900  C C   . VAL C 1 104 ? 136.549 114.256 120.550 1.00 69.93  ? 50  VAL C C   1 
ATOM   5901  O O   . VAL C 1 104 ? 136.982 114.265 121.707 1.00 77.67  ? 50  VAL C O   1 
ATOM   5902  C CB  . VAL C 1 104 ? 138.088 112.424 119.747 1.00 58.75  ? 50  VAL C CB  1 
ATOM   5903  C CG1 . VAL C 1 104 ? 137.042 111.375 120.062 1.00 60.37  ? 50  VAL C CG1 1 
ATOM   5904  C CG2 . VAL C 1 104 ? 138.973 111.963 118.601 1.00 54.09  ? 50  VAL C CG2 1 
ATOM   5905  N N   . SER C 1 105 ? 135.324 114.665 120.238 1.00 67.67  ? 51  SER C N   1 
ATOM   5906  C CA  . SER C 1 105 ? 134.445 115.310 121.203 1.00 70.44  ? 51  SER C CA  1 
ATOM   5907  C C   . SER C 1 105 ? 133.366 114.347 121.676 1.00 71.35  ? 51  SER C C   1 
ATOM   5908  O O   . SER C 1 105 ? 132.642 113.761 120.867 1.00 69.88  ? 51  SER C O   1 
ATOM   5909  C CB  . SER C 1 105 ? 133.797 116.556 120.595 1.00 69.86  ? 51  SER C CB  1 
ATOM   5910  O OG  . SER C 1 105 ? 132.943 117.195 121.526 1.00 70.15  ? 51  SER C OG  1 
ATOM   5911  N N   . GLU C 1 106 ? 133.265 114.188 122.995 1.00 73.25  ? 52  GLU C N   1 
ATOM   5912  C CA  . GLU C 1 106 ? 132.212 113.383 123.601 1.00 71.86  ? 52  GLU C CA  1 
ATOM   5913  C C   . GLU C 1 106 ? 130.858 114.075 123.606 1.00 72.69  ? 52  GLU C C   1 
ATOM   5914  O O   . GLU C 1 106 ? 129.832 113.400 123.475 1.00 73.29  ? 52  GLU C O   1 
ATOM   5915  C CB  . GLU C 1 106 ? 132.577 113.010 125.043 1.00 73.85  ? 52  GLU C CB  1 
ATOM   5916  C CG  . GLU C 1 106 ? 133.762 112.069 125.182 1.00 74.33  ? 52  GLU C CG  1 
ATOM   5917  C CD  . GLU C 1 106 ? 135.092 112.790 125.125 1.00 81.31  ? 52  GLU C CD  1 
ATOM   5918  O OE1 . GLU C 1 106 ? 135.093 114.037 125.045 1.00 80.76  ? 52  GLU C OE1 1 
ATOM   5919  O OE2 . GLU C 1 106 ? 136.139 112.110 125.164 1.00 81.08  ? 52  GLU C OE2 1 
ATOM   5920  N N   . VAL C 1 107 ? 130.832 115.398 123.767 1.00 73.75  ? 53  VAL C N   1 
ATOM   5921  C CA  . VAL C 1 107 ? 129.565 116.125 123.793 1.00 73.10  ? 53  VAL C CA  1 
ATOM   5922  C C   . VAL C 1 107 ? 128.870 116.033 122.440 1.00 76.29  ? 53  VAL C C   1 
ATOM   5923  O O   . VAL C 1 107 ? 127.681 115.709 122.351 1.00 78.37  ? 53  VAL C O   1 
ATOM   5924  C CB  . VAL C 1 107 ? 129.790 117.589 124.209 1.00 68.21  ? 53  VAL C CB  1 
ATOM   5925  C CG1 . VAL C 1 107 ? 128.482 118.357 124.170 1.00 67.30  ? 53  VAL C CG1 1 
ATOM   5926  C CG2 . VAL C 1 107 ? 130.408 117.654 125.594 1.00 76.50  ? 53  VAL C CG2 1 
ATOM   5927  N N   . ASN C 1 108 ? 129.606 116.313 121.366 1.00 72.84  ? 54  ASN C N   1 
ATOM   5928  C CA  . ASN C 1 108 ? 129.039 116.298 120.025 1.00 68.44  ? 54  ASN C CA  1 
ATOM   5929  C C   . ASN C 1 108 ? 128.965 114.902 119.421 1.00 70.66  ? 54  ASN C C   1 
ATOM   5930  O O   . ASN C 1 108 ? 128.332 114.739 118.372 1.00 72.16  ? 54  ASN C O   1 
ATOM   5931  C CB  . ASN C 1 108 ? 129.847 117.214 119.102 1.00 67.76  ? 54  ASN C CB  1 
ATOM   5932  C CG  . ASN C 1 108 ? 129.853 118.655 119.568 1.00 70.29  ? 54  ASN C CG  1 
ATOM   5933  O OD1 . ASN C 1 108 ? 128.947 119.425 119.250 1.00 76.39  ? 54  ASN C OD1 1 
ATOM   5934  N ND2 . ASN C 1 108 ? 130.882 119.031 120.316 1.00 69.00  ? 54  ASN C ND2 1 
ATOM   5935  N N   . MET C 1 109 ? 129.585 113.902 120.053 1.00 70.29  ? 55  MET C N   1 
ATOM   5936  C CA  . MET C 1 109 ? 129.618 112.537 119.536 1.00 69.67  ? 55  MET C CA  1 
ATOM   5937  C C   . MET C 1 109 ? 130.168 112.490 118.116 1.00 67.07  ? 55  MET C C   1 
ATOM   5938  O O   . MET C 1 109 ? 129.598 111.820 117.249 1.00 64.99  ? 55  MET C O   1 
ATOM   5939  C CB  . MET C 1 109 ? 128.224 111.906 119.575 1.00 66.39  ? 55  MET C CB  1 
ATOM   5940  C CG  . MET C 1 109 ? 127.699 111.616 120.968 1.00 71.87  ? 55  MET C CG  1 
ATOM   5941  S SD  . MET C 1 109 ? 128.649 110.343 121.816 1.00 82.74  ? 55  MET C SD  1 
ATOM   5942  C CE  . MET C 1 109 ? 127.617 110.057 123.248 1.00 72.43  ? 55  MET C CE  1 
ATOM   5943  N N   . ASP C 1 110 ? 131.270 113.191 117.866 1.00 63.61  ? 56  ASP C N   1 
ATOM   5944  C CA  . ASP C 1 110 ? 131.852 113.219 116.532 1.00 58.38  ? 56  ASP C CA  1 
ATOM   5945  C C   . ASP C 1 110 ? 133.342 113.504 116.646 1.00 61.99  ? 56  ASP C C   1 
ATOM   5946  O O   . ASP C 1 110 ? 133.827 113.960 117.685 1.00 67.14  ? 56  ASP C O   1 
ATOM   5947  C CB  . ASP C 1 110 ? 131.161 114.256 115.635 1.00 59.96  ? 56  ASP C CB  1 
ATOM   5948  C CG  . ASP C 1 110 ? 131.119 115.645 116.253 1.00 69.58  ? 56  ASP C CG  1 
ATOM   5949  O OD1 . ASP C 1 110 ? 131.936 115.941 117.150 1.00 72.12  ? 56  ASP C OD1 1 
ATOM   5950  O OD2 . ASP C 1 110 ? 130.256 116.448 115.839 1.00 75.04  ? 56  ASP C OD2 1 
ATOM   5951  N N   . TYR C 1 111 ? 134.059 113.217 115.565 1.00 57.92  ? 57  TYR C N   1 
ATOM   5952  C CA  . TYR C 1 111 ? 135.494 113.442 115.486 1.00 53.40  ? 57  TYR C CA  1 
ATOM   5953  C C   . TYR C 1 111 ? 135.830 114.127 114.170 1.00 54.54  ? 57  TYR C C   1 
ATOM   5954  O O   . TYR C 1 111 ? 135.226 113.833 113.136 1.00 59.63  ? 57  TYR C O   1 
ATOM   5955  C CB  . TYR C 1 111 ? 136.272 112.127 115.609 1.00 52.08  ? 57  TYR C CB  1 
ATOM   5956  C CG  . TYR C 1 111 ? 135.982 111.129 114.511 1.00 53.64  ? 57  TYR C CG  1 
ATOM   5957  C CD1 . TYR C 1 111 ? 134.857 110.319 114.562 1.00 55.08  ? 57  TYR C CD1 1 
ATOM   5958  C CD2 . TYR C 1 111 ? 136.838 110.990 113.429 1.00 56.21  ? 57  TYR C CD2 1 
ATOM   5959  C CE1 . TYR C 1 111 ? 134.588 109.407 113.562 1.00 59.39  ? 57  TYR C CE1 1 
ATOM   5960  C CE2 . TYR C 1 111 ? 136.578 110.081 112.426 1.00 56.86  ? 57  TYR C CE2 1 
ATOM   5961  C CZ  . TYR C 1 111 ? 135.452 109.291 112.498 1.00 59.42  ? 57  TYR C CZ  1 
ATOM   5962  O OH  . TYR C 1 111 ? 135.188 108.381 111.501 1.00 60.14  ? 57  TYR C OH  1 
ATOM   5963  N N   . THR C 1 112 ? 136.798 115.036 114.214 1.00 53.19  ? 58  THR C N   1 
ATOM   5964  C CA  . THR C 1 112 ? 137.250 115.757 113.034 1.00 54.52  ? 58  THR C CA  1 
ATOM   5965  C C   . THR C 1 112 ? 138.469 115.059 112.450 1.00 57.47  ? 58  THR C C   1 
ATOM   5966  O O   . THR C 1 112 ? 139.361 114.628 113.185 1.00 59.61  ? 58  THR C O   1 
ATOM   5967  C CB  . THR C 1 112 ? 137.584 117.209 113.373 1.00 57.30  ? 58  THR C CB  1 
ATOM   5968  O OG1 . THR C 1 112 ? 136.479 117.804 114.063 1.00 56.13  ? 58  THR C OG1 1 
ATOM   5969  C CG2 . THR C 1 112 ? 137.860 118.001 112.109 1.00 58.36  ? 58  THR C CG2 1 
ATOM   5970  N N   . LEU C 1 113 ? 138.506 114.956 111.124 1.00 56.11  ? 59  LEU C N   1 
ATOM   5971  C CA  . LEU C 1 113 ? 139.502 114.144 110.437 1.00 49.68  ? 59  LEU C CA  1 
ATOM   5972  C C   . LEU C 1 113 ? 139.906 114.837 109.145 1.00 50.80  ? 59  LEU C C   1 
ATOM   5973  O O   . LEU C 1 113 ? 139.049 115.142 108.313 1.00 52.38  ? 59  LEU C O   1 
ATOM   5974  C CB  . LEU C 1 113 ? 138.943 112.750 110.148 1.00 41.20  ? 59  LEU C CB  1 
ATOM   5975  C CG  . LEU C 1 113 ? 139.797 111.818 109.296 1.00 46.91  ? 59  LEU C CG  1 
ATOM   5976  C CD1 . LEU C 1 113 ? 141.081 111.510 110.023 1.00 51.75  ? 59  LEU C CD1 1 
ATOM   5977  C CD2 . LEU C 1 113 ? 139.036 110.543 108.985 1.00 53.96  ? 59  LEU C CD2 1 
ATOM   5978  N N   . THR C 1 114 ? 141.203 115.078 108.978 1.00 49.56  ? 60  THR C N   1 
ATOM   5979  C CA  . THR C 1 114 ? 141.754 115.648 107.755 1.00 45.23  ? 60  THR C CA  1 
ATOM   5980  C C   . THR C 1 114 ? 142.556 114.578 107.029 1.00 46.36  ? 60  THR C C   1 
ATOM   5981  O O   . THR C 1 114 ? 143.413 113.921 107.630 1.00 50.20  ? 60  THR C O   1 
ATOM   5982  C CB  . THR C 1 114 ? 142.635 116.862 108.055 1.00 50.35  ? 60  THR C CB  1 
ATOM   5983  O OG1 . THR C 1 114 ? 141.826 117.925 108.569 1.00 61.69  ? 60  THR C OG1 1 
ATOM   5984  C CG2 . THR C 1 114 ? 143.341 117.337 106.795 1.00 45.32  ? 60  THR C CG2 1 
ATOM   5985  N N   . MET C 1 115 ? 142.284 114.406 105.739 1.00 43.17  ? 61  MET C N   1 
ATOM   5986  C CA  . MET C 1 115 ? 142.870 113.290 105.015 1.00 39.02  ? 61  MET C CA  1 
ATOM   5987  C C   . MET C 1 115 ? 143.077 113.652 103.554 1.00 36.38  ? 61  MET C C   1 
ATOM   5988  O O   . MET C 1 115 ? 142.433 114.552 103.011 1.00 37.70  ? 61  MET C O   1 
ATOM   5989  C CB  . MET C 1 115 ? 141.990 112.043 105.122 1.00 42.56  ? 61  MET C CB  1 
ATOM   5990  C CG  . MET C 1 115 ? 140.567 112.270 104.653 1.00 40.60  ? 61  MET C CG  1 
ATOM   5991  S SD  . MET C 1 115 ? 139.520 110.827 104.870 1.00 54.97  ? 61  MET C SD  1 
ATOM   5992  C CE  . MET C 1 115 ? 137.919 111.540 104.524 1.00 47.84  ? 61  MET C CE  1 
ATOM   5993  N N   . TYR C 1 116 ? 144.003 112.932 102.928 1.00 36.26  ? 62  TYR C N   1 
ATOM   5994  C CA  . TYR C 1 116 ? 144.172 112.919 101.483 1.00 35.88  ? 62  TYR C CA  1 
ATOM   5995  C C   . TYR C 1 116 ? 143.451 111.682 100.967 1.00 40.95  ? 62  TYR C C   1 
ATOM   5996  O O   . TYR C 1 116 ? 143.890 110.555 101.210 1.00 49.39  ? 62  TYR C O   1 
ATOM   5997  C CB  . TYR C 1 116 ? 145.649 112.892 101.096 1.00 35.70  ? 62  TYR C CB  1 
ATOM   5998  C CG  . TYR C 1 116 ? 146.483 113.994 101.710 1.00 39.65  ? 62  TYR C CG  1 
ATOM   5999  C CD1 . TYR C 1 116 ? 146.985 113.876 102.997 1.00 41.41  ? 62  TYR C CD1 1 
ATOM   6000  C CD2 . TYR C 1 116 ? 146.785 115.142 100.994 1.00 41.84  ? 62  TYR C CD2 1 
ATOM   6001  C CE1 . TYR C 1 116 ? 147.752 114.876 103.558 1.00 42.04  ? 62  TYR C CE1 1 
ATOM   6002  C CE2 . TYR C 1 116 ? 147.553 116.145 101.547 1.00 45.38  ? 62  TYR C CE2 1 
ATOM   6003  C CZ  . TYR C 1 116 ? 148.033 116.007 102.829 1.00 50.68  ? 62  TYR C CZ  1 
ATOM   6004  O OH  . TYR C 1 116 ? 148.798 117.006 103.386 1.00 61.68  ? 62  TYR C OH  1 
ATOM   6005  N N   . PHE C 1 117 ? 142.347 111.894 100.268 1.00 32.36  ? 63  PHE C N   1 
ATOM   6006  C CA  . PHE C 1 117 ? 141.470 110.830 99.797  1.00 30.52  ? 63  PHE C CA  1 
ATOM   6007  C C   . PHE C 1 117 ? 141.669 110.699 98.294  1.00 29.66  ? 63  PHE C C   1 
ATOM   6008  O O   . PHE C 1 117 ? 141.326 111.614 97.540  1.00 35.51  ? 63  PHE C O   1 
ATOM   6009  C CB  . PHE C 1 117 ? 140.021 111.157 100.151 1.00 30.46  ? 63  PHE C CB  1 
ATOM   6010  C CG  . PHE C 1 117 ? 139.034 110.111 99.737  1.00 31.44  ? 63  PHE C CG  1 
ATOM   6011  C CD1 . PHE C 1 117 ? 138.882 108.955 100.477 1.00 37.17  ? 63  PHE C CD1 1 
ATOM   6012  C CD2 . PHE C 1 117 ? 138.237 110.298 98.622  1.00 30.92  ? 63  PHE C CD2 1 
ATOM   6013  C CE1 . PHE C 1 117 ? 137.969 107.995 100.103 1.00 37.81  ? 63  PHE C CE1 1 
ATOM   6014  C CE2 . PHE C 1 117 ? 137.321 109.343 98.245  1.00 32.96  ? 63  PHE C CE2 1 
ATOM   6015  C CZ  . PHE C 1 117 ? 137.187 108.190 98.987  1.00 37.38  ? 63  PHE C CZ  1 
ATOM   6016  N N   . GLN C 1 118 ? 142.245 109.582 97.855  1.00 30.25  ? 64  GLN C N   1 
ATOM   6017  C CA  . GLN C 1 118 ? 142.558 109.379 96.448  1.00 36.22  ? 64  GLN C CA  1 
ATOM   6018  C C   . GLN C 1 118 ? 141.724 108.235 95.895  1.00 37.82  ? 64  GLN C C   1 
ATOM   6019  O O   . GLN C 1 118 ? 141.624 107.172 96.517  1.00 40.64  ? 64  GLN C O   1 
ATOM   6020  C CB  . GLN C 1 118 ? 144.045 109.089 96.244  1.00 37.27  ? 64  GLN C CB  1 
ATOM   6021  C CG  . GLN C 1 118 ? 144.962 110.215 96.667  1.00 45.55  ? 64  GLN C CG  1 
ATOM   6022  C CD  . GLN C 1 118 ? 146.378 110.012 96.177  1.00 54.54  ? 64  GLN C CD  1 
ATOM   6023  O OE1 . GLN C 1 118 ? 146.652 109.091 95.409  1.00 52.07  ? 64  GLN C OE1 1 
ATOM   6024  N NE2 . GLN C 1 118 ? 147.289 110.871 96.618  1.00 65.36  ? 64  GLN C NE2 1 
ATOM   6025  N N   . GLN C 1 119 ? 141.129 108.463 94.730  1.00 34.60  ? 65  GLN C N   1 
ATOM   6026  C CA  . GLN C 1 119 ? 140.371 107.463 94.002  1.00 34.16  ? 65  GLN C CA  1 
ATOM   6027  C C   . GLN C 1 119 ? 141.092 107.149 92.700  1.00 38.93  ? 65  GLN C C   1 
ATOM   6028  O O   . GLN C 1 119 ? 141.798 107.992 92.141  1.00 44.18  ? 65  GLN C O   1 
ATOM   6029  C CB  . GLN C 1 119 ? 138.945 107.944 93.724  1.00 32.86  ? 65  GLN C CB  1 
ATOM   6030  C CG  . GLN C 1 119 ? 138.159 108.259 94.983  1.00 37.82  ? 65  GLN C CG  1 
ATOM   6031  C CD  . GLN C 1 119 ? 136.880 109.017 94.705  1.00 42.40  ? 65  GLN C CD  1 
ATOM   6032  O OE1 . GLN C 1 119 ? 135.915 108.461 94.182  1.00 48.27  ? 65  GLN C OE1 1 
ATOM   6033  N NE2 . GLN C 1 119 ? 136.864 110.296 95.057  1.00 41.82  ? 65  GLN C NE2 1 
ATOM   6034  N N   . TYR C 1 120 ? 140.913 105.922 92.228  1.00 39.22  ? 66  TYR C N   1 
ATOM   6035  C CA  . TYR C 1 120 ? 141.689 105.389 91.116  1.00 41.45  ? 66  TYR C CA  1 
ATOM   6036  C C   . TYR C 1 120 ? 140.759 104.536 90.275  1.00 43.29  ? 66  TYR C C   1 
ATOM   6037  O O   . TYR C 1 120 ? 140.237 103.531 90.766  1.00 50.82  ? 66  TYR C O   1 
ATOM   6038  C CB  . TYR C 1 120 ? 142.868 104.566 91.650  1.00 50.26  ? 66  TYR C CB  1 
ATOM   6039  C CG  . TYR C 1 120 ? 143.842 104.038 90.623  1.00 54.73  ? 66  TYR C CG  1 
ATOM   6040  C CD1 . TYR C 1 120 ? 143.543 102.916 89.863  1.00 56.69  ? 66  TYR C CD1 1 
ATOM   6041  C CD2 . TYR C 1 120 ? 145.082 104.635 90.449  1.00 57.62  ? 66  TYR C CD2 1 
ATOM   6042  C CE1 . TYR C 1 120 ? 144.438 102.423 88.937  1.00 62.90  ? 66  TYR C CE1 1 
ATOM   6043  C CE2 . TYR C 1 120 ? 145.984 104.147 89.527  1.00 64.79  ? 66  TYR C CE2 1 
ATOM   6044  C CZ  . TYR C 1 120 ? 145.658 103.039 88.777  1.00 68.54  ? 66  TYR C CZ  1 
ATOM   6045  O OH  . TYR C 1 120 ? 146.554 102.551 87.854  1.00 73.22  ? 66  TYR C OH  1 
ATOM   6046  N N   . TRP C 1 121 ? 140.527 104.936 89.026  1.00 42.15  ? 67  TRP C N   1 
ATOM   6047  C CA  . TRP C 1 121 ? 139.643 104.164 88.162  1.00 43.32  ? 67  TRP C CA  1 
ATOM   6048  C C   . TRP C 1 121 ? 140.172 104.209 86.738  1.00 44.51  ? 67  TRP C C   1 
ATOM   6049  O O   . TRP C 1 121 ? 141.212 104.807 86.463  1.00 52.14  ? 67  TRP C O   1 
ATOM   6050  C CB  . TRP C 1 121 ? 138.193 104.662 88.254  1.00 44.20  ? 67  TRP C CB  1 
ATOM   6051  C CG  . TRP C 1 121 ? 137.935 106.003 87.641  1.00 42.75  ? 67  TRP C CG  1 
ATOM   6052  C CD1 . TRP C 1 121 ? 137.539 106.253 86.362  1.00 46.80  ? 67  TRP C CD1 1 
ATOM   6053  C CD2 . TRP C 1 121 ? 138.022 107.277 88.289  1.00 40.18  ? 67  TRP C CD2 1 
ATOM   6054  N NE1 . TRP C 1 121 ? 137.387 107.603 86.167  1.00 45.69  ? 67  TRP C NE1 1 
ATOM   6055  C CE2 . TRP C 1 121 ? 137.678 108.254 87.336  1.00 36.87  ? 67  TRP C CE2 1 
ATOM   6056  C CE3 . TRP C 1 121 ? 138.366 107.686 89.580  1.00 40.88  ? 67  TRP C CE3 1 
ATOM   6057  C CZ2 . TRP C 1 121 ? 137.665 109.613 87.633  1.00 36.91  ? 67  TRP C CZ2 1 
ATOM   6058  C CZ3 . TRP C 1 121 ? 138.355 109.033 89.871  1.00 38.49  ? 67  TRP C CZ3 1 
ATOM   6059  C CH2 . TRP C 1 121 ? 138.007 109.982 88.903  1.00 36.67  ? 67  TRP C CH2 1 
ATOM   6060  N N   . ARG C 1 122 ? 139.462 103.552 85.826  1.00 47.68  ? 68  ARG C N   1 
ATOM   6061  C CA  . ARG C 1 122 ? 139.850 103.508 84.423  1.00 55.02  ? 68  ARG C CA  1 
ATOM   6062  C C   . ARG C 1 122 ? 138.715 104.046 83.567  1.00 60.86  ? 68  ARG C C   1 
ATOM   6063  O O   . ARG C 1 122 ? 137.554 103.673 83.762  1.00 67.37  ? 68  ARG C O   1 
ATOM   6064  C CB  . ARG C 1 122 ? 140.210 102.087 83.982  1.00 54.64  ? 68  ARG C CB  1 
ATOM   6065  C CG  . ARG C 1 122 ? 140.788 102.024 82.577  1.00 59.48  ? 68  ARG C CG  1 
ATOM   6066  C CD  . ARG C 1 122 ? 141.041 100.596 82.125  1.00 73.85  ? 68  ARG C CD  1 
ATOM   6067  N NE  . ARG C 1 122 ? 141.669 100.555 80.809  1.00 85.15  ? 68  ARG C NE  1 
ATOM   6068  C CZ  . ARG C 1 122 ? 141.915 99.445  80.127  1.00 89.00  ? 68  ARG C CZ  1 
ATOM   6069  N NH1 . ARG C 1 122 ? 141.585 98.255  80.601  1.00 92.92  ? 68  ARG C NH1 1 
ATOM   6070  N NH2 . ARG C 1 122 ? 142.505 99.532  78.939  1.00 84.86  ? 68  ARG C NH2 1 
ATOM   6071  N N   . ASP C 1 123 ? 139.054 104.922 82.625  1.00 60.97  ? 69  ASP C N   1 
ATOM   6072  C CA  . ASP C 1 123 ? 138.087 105.472 81.680  1.00 59.44  ? 69  ASP C CA  1 
ATOM   6073  C C   . ASP C 1 123 ? 138.724 105.426 80.299  1.00 65.32  ? 69  ASP C C   1 
ATOM   6074  O O   . ASP C 1 123 ? 139.649 106.192 80.017  1.00 71.46  ? 69  ASP C O   1 
ATOM   6075  C CB  . ASP C 1 123 ? 137.687 106.898 82.060  1.00 58.12  ? 69  ASP C CB  1 
ATOM   6076  C CG  . ASP C 1 123 ? 136.418 107.354 81.369  1.00 67.17  ? 69  ASP C CG  1 
ATOM   6077  O OD1 . ASP C 1 123 ? 135.918 106.621 80.490  1.00 74.09  ? 69  ASP C OD1 1 
ATOM   6078  O OD2 . ASP C 1 123 ? 135.913 108.443 81.712  1.00 69.48  ? 69  ASP C OD2 1 
ATOM   6079  N N   . LYS C 1 124 ? 138.232 104.527 79.444  1.00 65.32  ? 70  LYS C N   1 
ATOM   6080  C CA  . LYS C 1 124 ? 138.839 104.343 78.129  1.00 69.40  ? 70  LYS C CA  1 
ATOM   6081  C C   . LYS C 1 124 ? 138.699 105.585 77.259  1.00 69.48  ? 70  LYS C C   1 
ATOM   6082  O O   . LYS C 1 124 ? 139.502 105.788 76.341  1.00 72.39  ? 70  LYS C O   1 
ATOM   6083  C CB  . LYS C 1 124 ? 138.224 103.131 77.432  1.00 73.61  ? 70  LYS C CB  1 
ATOM   6084  C CG  . LYS C 1 124 ? 138.476 101.819 78.155  1.00 83.56  ? 70  LYS C CG  1 
ATOM   6085  C CD  . LYS C 1 124 ? 137.883 100.645 77.399  1.00 95.12  ? 70  LYS C CD  1 
ATOM   6086  C CE  . LYS C 1 124 ? 138.128 99.338  78.133  1.00 93.18  ? 70  LYS C CE  1 
ATOM   6087  N NZ  . LYS C 1 124 ? 137.520 98.184  77.416  1.00 92.28  ? 70  LYS C NZ  1 
ATOM   6088  N N   . ARG C 1 125 ? 137.694 106.420 77.524  1.00 68.65  ? 71  ARG C N   1 
ATOM   6089  C CA  . ARG C 1 125 ? 137.525 107.649 76.758  1.00 68.64  ? 71  ARG C CA  1 
ATOM   6090  C C   . ARG C 1 125 ? 138.685 108.614 76.952  1.00 68.31  ? 71  ARG C C   1 
ATOM   6091  O O   . ARG C 1 125 ? 138.903 109.482 76.100  1.00 71.13  ? 71  ARG C O   1 
ATOM   6092  C CB  . ARG C 1 125 ? 136.216 108.331 77.144  1.00 63.18  ? 71  ARG C CB  1 
ATOM   6093  C CG  . ARG C 1 125 ? 134.985 107.482 76.911  1.00 62.04  ? 71  ARG C CG  1 
ATOM   6094  C CD  . ARG C 1 125 ? 133.757 108.153 77.490  1.00 66.56  ? 71  ARG C CD  1 
ATOM   6095  N NE  . ARG C 1 125 ? 133.888 108.365 78.926  1.00 65.34  ? 71  ARG C NE  1 
ATOM   6096  C CZ  . ARG C 1 125 ? 132.966 108.940 79.685  1.00 65.30  ? 71  ARG C CZ  1 
ATOM   6097  N NH1 . ARG C 1 125 ? 131.830 109.385 79.174  1.00 66.69  ? 71  ARG C NH1 1 
ATOM   6098  N NH2 . ARG C 1 125 ? 133.189 109.071 80.990  1.00 60.08  ? 71  ARG C NH2 1 
ATOM   6099  N N   . LEU C 1 126 ? 139.430 108.486 78.048  1.00 67.57  ? 72  LEU C N   1 
ATOM   6100  C CA  . LEU C 1 126 ? 140.552 109.363 78.344  1.00 70.25  ? 72  LEU C CA  1 
ATOM   6101  C C   . LEU C 1 126 ? 141.895 108.729 78.016  1.00 73.31  ? 72  LEU C C   1 
ATOM   6102  O O   . LEU C 1 126 ? 142.932 109.243 78.446  1.00 75.40  ? 72  LEU C O   1 
ATOM   6103  C CB  . LEU C 1 126 ? 140.515 109.782 79.814  1.00 61.56  ? 72  LEU C CB  1 
ATOM   6104  C CG  . LEU C 1 126 ? 139.256 110.537 80.236  1.00 60.65  ? 72  LEU C CG  1 
ATOM   6105  C CD1 . LEU C 1 126 ? 139.312 110.894 81.708  1.00 57.50  ? 72  LEU C CD1 1 
ATOM   6106  C CD2 . LEU C 1 126 ? 139.086 111.782 79.387  1.00 64.20  ? 72  LEU C CD2 1 
ATOM   6107  N N   . ALA C 1 127 ? 141.902 107.624 77.276  1.00 72.05  ? 73  ALA C N   1 
ATOM   6108  C CA  . ALA C 1 127 ? 143.146 106.978 76.888  1.00 74.21  ? 73  ALA C CA  1 
ATOM   6109  C C   . ALA C 1 127 ? 143.791 107.735 75.736  1.00 75.23  ? 73  ALA C C   1 
ATOM   6110  O O   . ALA C 1 127 ? 143.127 108.067 74.749  1.00 76.06  ? 73  ALA C O   1 
ATOM   6111  C CB  . ALA C 1 127 ? 142.891 105.524 76.494  1.00 72.76  ? 73  ALA C CB  1 
ATOM   6112  N N   . TYR C 1 128 ? 145.088 108.004 75.860  1.00 72.96  ? 74  TYR C N   1 
ATOM   6113  C CA  . TYR C 1 128 ? 145.831 108.730 74.843  1.00 76.87  ? 74  TYR C CA  1 
ATOM   6114  C C   . TYR C 1 128 ? 147.094 107.960 74.487  1.00 82.30  ? 74  TYR C C   1 
ATOM   6115  O O   . TYR C 1 128 ? 147.596 107.149 75.269  1.00 82.23  ? 74  TYR C O   1 
ATOM   6116  C CB  . TYR C 1 128 ? 146.187 110.150 75.306  1.00 75.70  ? 74  TYR C CB  1 
ATOM   6117  C CG  . TYR C 1 128 ? 147.090 110.199 76.516  1.00 73.81  ? 74  TYR C CG  1 
ATOM   6118  C CD1 . TYR C 1 128 ? 146.565 110.145 77.798  1.00 73.56  ? 74  TYR C CD1 1 
ATOM   6119  C CD2 . TYR C 1 128 ? 148.465 110.306 76.376  1.00 77.26  ? 74  TYR C CD2 1 
ATOM   6120  C CE1 . TYR C 1 128 ? 147.386 110.191 78.906  1.00 74.13  ? 74  TYR C CE1 1 
ATOM   6121  C CE2 . TYR C 1 128 ? 149.293 110.351 77.477  1.00 78.44  ? 74  TYR C CE2 1 
ATOM   6122  C CZ  . TYR C 1 128 ? 148.748 110.294 78.739  1.00 76.38  ? 74  TYR C CZ  1 
ATOM   6123  O OH  . TYR C 1 128 ? 149.568 110.340 79.839  1.00 80.51  ? 74  TYR C OH  1 
ATOM   6124  N N   . SER C 1 129 ? 147.602 108.226 73.286  1.00 88.15  ? 75  SER C N   1 
ATOM   6125  C CA  . SER C 1 129 ? 148.786 107.561 72.768  1.00 88.59  ? 75  SER C CA  1 
ATOM   6126  C C   . SER C 1 129 ? 149.739 108.596 72.188  1.00 93.84  ? 75  SER C C   1 
ATOM   6127  O O   . SER C 1 129 ? 149.335 109.693 71.796  1.00 94.59  ? 75  SER C O   1 
ATOM   6128  C CB  . SER C 1 129 ? 148.424 106.523 71.699  1.00 88.26  ? 75  SER C CB  1 
ATOM   6129  O OG  . SER C 1 129 ? 147.754 107.132 70.608  1.00 95.00  ? 75  SER C OG  1 
ATOM   6130  N N   . GLY C 1 130 ? 151.018 108.229 72.139  1.00 94.92  ? 76  GLY C N   1 
ATOM   6131  C CA  . GLY C 1 130 ? 152.062 109.092 71.641  1.00 99.95  ? 76  GLY C CA  1 
ATOM   6132  C C   . GLY C 1 130 ? 152.832 109.834 72.713  1.00 102.30 ? 76  GLY C C   1 
ATOM   6133  O O   . GLY C 1 130 ? 153.939 110.312 72.443  1.00 106.11 ? 76  GLY C O   1 
ATOM   6134  N N   . ILE C 1 131 ? 152.281 109.939 73.915  1.00 99.36  ? 77  ILE C N   1 
ATOM   6135  C CA  . ILE C 1 131 ? 152.932 110.605 75.033  1.00 99.00  ? 77  ILE C CA  1 
ATOM   6136  C C   . ILE C 1 131 ? 153.162 109.575 76.131  1.00 103.27 ? 77  ILE C C   1 
ATOM   6137  O O   . ILE C 1 131 ? 152.252 109.249 76.893  1.00 104.59 ? 77  ILE C O   1 
ATOM   6138  C CB  . ILE C 1 131 ? 152.095 111.788 75.551  1.00 93.62  ? 77  ILE C CB  1 
ATOM   6139  C CG1 . ILE C 1 131 ? 151.763 112.742 74.405  1.00 97.12  ? 77  ILE C CG1 1 
ATOM   6140  C CG2 . ILE C 1 131 ? 152.841 112.520 76.655  1.00 93.76  ? 77  ILE C CG2 1 
ATOM   6141  C CD1 . ILE C 1 131 ? 150.893 113.907 74.811  1.00 98.22  ? 77  ILE C CD1 1 
ATOM   6142  N N   . PRO C 1 132 ? 154.377 109.034 76.242  1.00 102.84 ? 78  PRO C N   1 
ATOM   6143  C CA  . PRO C 1 132 ? 154.694 108.045 77.280  1.00 102.06 ? 78  PRO C CA  1 
ATOM   6144  C C   . PRO C 1 132 ? 154.943 108.667 78.653  1.00 101.30 ? 78  PRO C C   1 
ATOM   6145  O O   . PRO C 1 132 ? 155.907 108.332 79.343  1.00 101.01 ? 78  PRO C O   1 
ATOM   6146  C CB  . PRO C 1 132 ? 155.951 107.369 76.726  1.00 100.82 ? 78  PRO C CB  1 
ATOM   6147  C CG  . PRO C 1 132 ? 156.619 108.444 75.941  1.00 100.66 ? 78  PRO C CG  1 
ATOM   6148  C CD  . PRO C 1 132 ? 155.516 109.274 75.338  1.00 99.38  ? 78  PRO C CD  1 
ATOM   6149  N N   . LEU C 1 133 ? 154.061 109.580 79.054  1.00 98.46  ? 79  LEU C N   1 
ATOM   6150  C CA  . LEU C 1 133 ? 154.174 110.268 80.330  1.00 94.24  ? 79  LEU C CA  1 
ATOM   6151  C C   . LEU C 1 133 ? 152.809 110.323 80.996  1.00 88.94  ? 79  LEU C C   1 
ATOM   6152  O O   . LEU C 1 133 ? 151.775 110.361 80.325  1.00 90.94  ? 79  LEU C O   1 
ATOM   6153  C CB  . LEU C 1 133 ? 154.722 111.692 80.164  1.00 96.23  ? 79  LEU C CB  1 
ATOM   6154  C CG  . LEU C 1 133 ? 156.093 111.861 79.510  1.00 103.06 ? 79  LEU C CG  1 
ATOM   6155  C CD1 . LEU C 1 133 ? 156.410 113.335 79.324  1.00 105.49 ? 79  LEU C CD1 1 
ATOM   6156  C CD2 . LEU C 1 133 ? 157.170 111.180 80.339  1.00 99.41  ? 79  LEU C CD2 1 
ATOM   6157  N N   . ASN C 1 134 ? 152.817 110.330 82.325  1.00 85.92  ? 80  ASN C N   1 
ATOM   6158  C CA  . ASN C 1 134 ? 151.596 110.533 83.092  1.00 81.21  ? 80  ASN C CA  1 
ATOM   6159  C C   . ASN C 1 134 ? 151.296 112.025 83.153  1.00 79.50  ? 80  ASN C C   1 
ATOM   6160  O O   . ASN C 1 134 ? 152.121 112.809 83.633  1.00 79.77  ? 80  ASN C O   1 
ATOM   6161  C CB  . ASN C 1 134 ? 151.743 109.947 84.493  1.00 82.02  ? 80  ASN C CB  1 
ATOM   6162  C CG  . ASN C 1 134 ? 151.866 108.437 84.482  1.00 85.13  ? 80  ASN C CG  1 
ATOM   6163  O OD1 . ASN C 1 134 ? 151.266 107.762 83.648  1.00 84.19  ? 80  ASN C OD1 1 
ATOM   6164  N ND2 . ASN C 1 134 ? 152.648 107.897 85.410  1.00 93.04  ? 80  ASN C ND2 1 
ATOM   6165  N N   . LEU C 1 135 ? 150.122 112.419 82.669  1.00 74.98  ? 81  LEU C N   1 
ATOM   6166  C CA  . LEU C 1 135 ? 149.766 113.829 82.555  1.00 66.93  ? 81  LEU C CA  1 
ATOM   6167  C C   . LEU C 1 135 ? 149.162 114.298 83.872  1.00 63.75  ? 81  LEU C C   1 
ATOM   6168  O O   . LEU C 1 135 ? 148.026 113.945 84.202  1.00 67.84  ? 81  LEU C O   1 
ATOM   6169  C CB  . LEU C 1 135 ? 148.790 114.052 81.402  1.00 64.78  ? 81  LEU C CB  1 
ATOM   6170  C CG  . LEU C 1 135 ? 149.229 113.586 80.014  1.00 68.44  ? 81  LEU C CG  1 
ATOM   6171  C CD1 . LEU C 1 135 ? 148.218 114.019 78.965  1.00 63.28  ? 81  LEU C CD1 1 
ATOM   6172  C CD2 . LEU C 1 135 ? 150.614 114.110 79.677  1.00 76.21  ? 81  LEU C CD2 1 
ATOM   6173  N N   . THR C 1 136 ? 149.919 115.087 84.628  1.00 60.65  ? 82  THR C N   1 
ATOM   6174  C CA  . THR C 1 136 ? 149.403 115.714 85.841  1.00 61.63  ? 82  THR C CA  1 
ATOM   6175  C C   . THR C 1 136 ? 148.748 117.026 85.435  1.00 59.26  ? 82  THR C C   1 
ATOM   6176  O O   . THR C 1 136 ? 149.429 118.029 85.210  1.00 63.22  ? 82  THR C O   1 
ATOM   6177  C CB  . THR C 1 136 ? 150.521 115.938 86.852  1.00 67.40  ? 82  THR C CB  1 
ATOM   6178  O OG1 . THR C 1 136 ? 151.154 114.689 87.152  1.00 66.96  ? 82  THR C OG1 1 
ATOM   6179  C CG2 . THR C 1 136 ? 149.967 116.539 88.133  1.00 65.50  ? 82  THR C CG2 1 
ATOM   6180  N N   . LEU C 1 137 ? 147.423 117.029 85.335  1.00 56.15  ? 83  LEU C N   1 
ATOM   6181  C CA  . LEU C 1 137 ? 146.733 118.192 84.802  1.00 57.37  ? 83  LEU C CA  1 
ATOM   6182  C C   . LEU C 1 137 ? 146.352 119.158 85.918  1.00 63.61  ? 83  LEU C C   1 
ATOM   6183  O O   . LEU C 1 137 ? 146.360 118.817 87.102  1.00 64.23  ? 83  LEU C O   1 
ATOM   6184  C CB  . LEU C 1 137 ? 145.486 117.771 84.026  1.00 52.04  ? 83  LEU C CB  1 
ATOM   6185  C CG  . LEU C 1 137 ? 145.713 116.887 82.800  1.00 49.67  ? 83  LEU C CG  1 
ATOM   6186  C CD1 . LEU C 1 137 ? 144.394 116.574 82.117  1.00 45.44  ? 83  LEU C CD1 1 
ATOM   6187  C CD2 . LEU C 1 137 ? 146.673 117.554 81.832  1.00 53.06  ? 83  LEU C CD2 1 
ATOM   6188  N N   . ASP C 1 138 ? 146.023 120.383 85.516  1.00 61.45  ? 84  ASP C N   1 
ATOM   6189  C CA  . ASP C 1 138 ? 145.552 121.381 86.463  1.00 60.72  ? 84  ASP C CA  1 
ATOM   6190  C C   . ASP C 1 138 ? 144.249 120.918 87.105  1.00 65.21  ? 84  ASP C C   1 
ATOM   6191  O O   . ASP C 1 138 ? 143.440 120.222 86.487  1.00 68.83  ? 84  ASP C O   1 
ATOM   6192  C CB  . ASP C 1 138 ? 145.352 122.724 85.761  1.00 62.29  ? 84  ASP C CB  1 
ATOM   6193  C CG  . ASP C 1 138 ? 145.009 123.841 86.722  1.00 66.46  ? 84  ASP C CG  1 
ATOM   6194  O OD1 . ASP C 1 138 ? 145.927 124.340 87.406  1.00 70.65  ? 84  ASP C OD1 1 
ATOM   6195  O OD2 . ASP C 1 138 ? 143.823 124.222 86.793  1.00 63.27  ? 84  ASP C OD2 1 
ATOM   6196  N N   . ASN C 1 139 ? 144.057 121.307 88.368  1.00 62.08  ? 85  ASN C N   1 
ATOM   6197  C CA  . ASN C 1 139 ? 142.914 120.824 89.137  1.00 59.94  ? 85  ASN C CA  1 
ATOM   6198  C C   . ASN C 1 139 ? 141.585 121.170 88.476  1.00 63.09  ? 85  ASN C C   1 
ATOM   6199  O O   . ASN C 1 139 ? 140.626 120.395 88.571  1.00 64.85  ? 85  ASN C O   1 
ATOM   6200  C CB  . ASN C 1 139 ? 142.962 121.397 90.553  1.00 55.41  ? 85  ASN C CB  1 
ATOM   6201  C CG  . ASN C 1 139 ? 142.982 122.910 90.566  1.00 60.47  ? 85  ASN C CG  1 
ATOM   6202  O OD1 . ASN C 1 139 ? 141.936 123.556 90.615  1.00 65.17  ? 85  ASN C OD1 1 
ATOM   6203  N ND2 . ASN C 1 139 ? 144.177 123.486 90.522  1.00 57.59  ? 85  ASN C ND2 1 
ATOM   6204  N N   . ARG C 1 140 ? 141.510 122.319 87.799  1.00 62.39  ? 86  ARG C N   1 
ATOM   6205  C CA  . ARG C 1 140 ? 140.245 122.762 87.222  1.00 61.67  ? 86  ARG C CA  1 
ATOM   6206  C C   . ARG C 1 140 ? 139.712 121.782 86.184  1.00 65.18  ? 86  ARG C C   1 
ATOM   6207  O O   . ARG C 1 140 ? 138.495 121.699 85.981  1.00 67.51  ? 86  ARG C O   1 
ATOM   6208  C CB  . ARG C 1 140 ? 140.411 124.154 86.613  1.00 61.92  ? 86  ARG C CB  1 
ATOM   6209  C CG  . ARG C 1 140 ? 140.342 125.277 87.635  1.00 65.69  ? 86  ARG C CG  1 
ATOM   6210  C CD  . ARG C 1 140 ? 140.861 126.587 87.070  1.00 59.92  ? 86  ARG C CD  1 
ATOM   6211  N NE  . ARG C 1 140 ? 142.318 126.631 87.053  1.00 58.13  ? 86  ARG C NE  1 
ATOM   6212  C CZ  . ARG C 1 140 ? 143.033 127.708 86.755  1.00 60.90  ? 86  ARG C CZ  1 
ATOM   6213  N NH1 . ARG C 1 140 ? 142.454 128.851 86.427  1.00 66.44  ? 86  ARG C NH1 1 
ATOM   6214  N NH2 . ARG C 1 140 ? 144.360 127.636 86.791  1.00 58.80  ? 86  ARG C NH2 1 
ATOM   6215  N N   . VAL C 1 141 ? 140.595 121.020 85.532  1.00 64.34  ? 87  VAL C N   1 
ATOM   6216  C CA  . VAL C 1 141 ? 140.142 120.054 84.538  1.00 62.62  ? 87  VAL C CA  1 
ATOM   6217  C C   . VAL C 1 141 ? 139.251 118.993 85.163  1.00 63.34  ? 87  VAL C C   1 
ATOM   6218  O O   . VAL C 1 141 ? 138.487 118.330 84.453  1.00 64.39  ? 87  VAL C O   1 
ATOM   6219  C CB  . VAL C 1 141 ? 141.339 119.403 83.813  1.00 54.76  ? 87  VAL C CB  1 
ATOM   6220  C CG1 . VAL C 1 141 ? 141.881 118.233 84.614  1.00 53.29  ? 87  VAL C CG1 1 
ATOM   6221  C CG2 . VAL C 1 141 ? 140.928 118.950 82.424  1.00 58.10  ? 87  VAL C CG2 1 
ATOM   6222  N N   . ALA C 1 142 ? 139.315 118.824 86.487  1.00 64.34  ? 88  ALA C N   1 
ATOM   6223  C CA  . ALA C 1 142 ? 138.432 117.878 87.158  1.00 63.23  ? 88  ALA C CA  1 
ATOM   6224  C C   . ALA C 1 142 ? 136.966 118.245 86.988  1.00 66.99  ? 88  ALA C C   1 
ATOM   6225  O O   . ALA C 1 142 ? 136.097 117.389 87.185  1.00 69.25  ? 88  ALA C O   1 
ATOM   6226  C CB  . ALA C 1 142 ? 138.779 117.793 88.643  1.00 58.33  ? 88  ALA C CB  1 
ATOM   6227  N N   . ASP C 1 143 ? 136.671 119.498 86.632  1.00 68.55  ? 89  ASP C N   1 
ATOM   6228  C CA  . ASP C 1 143 ? 135.294 119.902 86.387  1.00 67.65  ? 89  ASP C CA  1 
ATOM   6229  C C   . ASP C 1 143 ? 134.783 119.455 85.025  1.00 61.25  ? 89  ASP C C   1 
ATOM   6230  O O   . ASP C 1 143 ? 133.592 119.629 84.745  1.00 63.69  ? 89  ASP C O   1 
ATOM   6231  C CB  . ASP C 1 143 ? 135.163 121.420 86.508  1.00 71.93  ? 89  ASP C CB  1 
ATOM   6232  C CG  . ASP C 1 143 ? 135.668 121.942 87.835  1.00 77.25  ? 89  ASP C CG  1 
ATOM   6233  O OD1 . ASP C 1 143 ? 136.099 121.123 88.672  1.00 77.16  ? 89  ASP C OD1 1 
ATOM   6234  O OD2 . ASP C 1 143 ? 135.636 123.173 88.041  1.00 81.18  ? 89  ASP C OD2 1 
ATOM   6235  N N   . GLN C 1 144 ? 135.641 118.889 84.178  1.00 59.90  ? 90  GLN C N   1 
ATOM   6236  C CA  . GLN C 1 144 ? 135.258 118.484 82.833  1.00 60.37  ? 90  GLN C CA  1 
ATOM   6237  C C   . GLN C 1 144 ? 135.294 116.973 82.641  1.00 65.45  ? 90  GLN C C   1 
ATOM   6238  O O   . GLN C 1 144 ? 135.119 116.497 81.515  1.00 64.58  ? 90  GLN C O   1 
ATOM   6239  C CB  . GLN C 1 144 ? 136.161 119.166 81.804  1.00 62.64  ? 90  GLN C CB  1 
ATOM   6240  C CG  . GLN C 1 144 ? 136.263 120.669 81.986  1.00 68.50  ? 90  GLN C CG  1 
ATOM   6241  C CD  . GLN C 1 144 ? 137.083 121.335 80.903  1.00 75.63  ? 90  GLN C CD  1 
ATOM   6242  O OE1 . GLN C 1 144 ? 137.194 120.823 79.790  1.00 70.88  ? 90  GLN C OE1 1 
ATOM   6243  N NE2 . GLN C 1 144 ? 137.668 122.482 81.225  1.00 78.87  ? 90  GLN C NE2 1 
ATOM   6244  N N   . LEU C 1 145 ? 135.517 116.211 83.708  1.00 64.14  ? 91  LEU C N   1 
ATOM   6245  C CA  . LEU C 1 145 ? 135.573 114.761 83.648  1.00 57.30  ? 91  LEU C CA  1 
ATOM   6246  C C   . LEU C 1 145 ? 134.483 114.164 84.526  1.00 56.34  ? 91  LEU C C   1 
ATOM   6247  O O   . LEU C 1 145 ? 133.972 114.810 85.443  1.00 58.16  ? 91  LEU C O   1 
ATOM   6248  C CB  . LEU C 1 145 ? 136.937 114.232 84.108  1.00 52.11  ? 91  LEU C CB  1 
ATOM   6249  C CG  . LEU C 1 145 ? 138.186 114.757 83.404  1.00 53.51  ? 91  LEU C CG  1 
ATOM   6250  C CD1 . LEU C 1 145 ? 139.434 114.202 84.068  1.00 53.08  ? 91  LEU C CD1 1 
ATOM   6251  C CD2 . LEU C 1 145 ? 138.156 114.391 81.937  1.00 62.85  ? 91  LEU C CD2 1 
ATOM   6252  N N   . TRP C 1 146 ? 134.130 112.916 84.232  1.00 53.81  ? 92  TRP C N   1 
ATOM   6253  C CA  . TRP C 1 146 ? 133.283 112.157 85.140  1.00 49.90  ? 92  TRP C CA  1 
ATOM   6254  C C   . TRP C 1 146 ? 134.102 111.727 86.348  1.00 50.18  ? 92  TRP C C   1 
ATOM   6255  O O   . TRP C 1 146 ? 135.217 111.219 86.206  1.00 50.70  ? 92  TRP C O   1 
ATOM   6256  C CB  . TRP C 1 146 ? 132.695 110.934 84.441  1.00 50.10  ? 92  TRP C CB  1 
ATOM   6257  C CG  . TRP C 1 146 ? 131.863 110.062 85.347  1.00 51.69  ? 92  TRP C CG  1 
ATOM   6258  C CD1 . TRP C 1 146 ? 130.509 110.101 85.502  1.00 52.67  ? 92  TRP C CD1 1 
ATOM   6259  C CD2 . TRP C 1 146 ? 132.335 109.026 86.219  1.00 49.35  ? 92  TRP C CD2 1 
ATOM   6260  N NE1 . TRP C 1 146 ? 130.108 109.155 86.414  1.00 51.44  ? 92  TRP C NE1 1 
ATOM   6261  C CE2 . TRP C 1 146 ? 131.211 108.482 86.869  1.00 48.55  ? 92  TRP C CE2 1 
ATOM   6262  C CE3 . TRP C 1 146 ? 133.600 108.507 86.515  1.00 47.50  ? 92  TRP C CE3 1 
ATOM   6263  C CZ2 . TRP C 1 146 ? 131.311 107.447 87.794  1.00 47.03  ? 92  TRP C CZ2 1 
ATOM   6264  C CZ3 . TRP C 1 146 ? 133.697 107.480 87.430  1.00 46.38  ? 92  TRP C CZ3 1 
ATOM   6265  C CH2 . TRP C 1 146 ? 132.560 106.960 88.059  1.00 47.75  ? 92  TRP C CH2 1 
ATOM   6266  N N   . VAL C 1 147 ? 133.549 111.934 87.536  1.00 48.61  ? 93  VAL C N   1 
ATOM   6267  C CA  . VAL C 1 147 ? 134.195 111.492 88.767  1.00 47.49  ? 93  VAL C CA  1 
ATOM   6268  C C   . VAL C 1 147 ? 133.158 110.737 89.588  1.00 52.48  ? 93  VAL C C   1 
ATOM   6269  O O   . VAL C 1 147 ? 131.960 111.043 89.496  1.00 53.16  ? 93  VAL C O   1 
ATOM   6270  C CB  . VAL C 1 147 ? 134.788 112.674 89.548  1.00 46.23  ? 93  VAL C CB  1 
ATOM   6271  C CG1 . VAL C 1 147 ? 135.976 113.254 88.804  1.00 43.98  ? 93  VAL C CG1 1 
ATOM   6272  C CG2 . VAL C 1 147 ? 133.733 113.739 89.771  1.00 47.91  ? 93  VAL C CG2 1 
ATOM   6273  N N   . PRO C 1 148 ? 133.557 109.743 90.378  1.00 48.35  ? 94  PRO C N   1 
ATOM   6274  C CA  . PRO C 1 148 ? 132.573 109.007 91.175  1.00 44.19  ? 94  PRO C CA  1 
ATOM   6275  C C   . PRO C 1 148 ? 131.899 109.917 92.188  1.00 48.17  ? 94  PRO C C   1 
ATOM   6276  O O   . PRO C 1 148 ? 132.506 110.845 92.725  1.00 50.97  ? 94  PRO C O   1 
ATOM   6277  C CB  . PRO C 1 148 ? 133.410 107.923 91.863  1.00 44.73  ? 94  PRO C CB  1 
ATOM   6278  C CG  . PRO C 1 148 ? 134.641 107.803 91.031  1.00 46.31  ? 94  PRO C CG  1 
ATOM   6279  C CD  . PRO C 1 148 ? 134.908 109.180 90.515  1.00 44.70  ? 94  PRO C CD  1 
ATOM   6280  N N   . ASP C 1 149 ? 130.623 109.639 92.444  1.00 47.09  ? 95  ASP C N   1 
ATOM   6281  C CA  . ASP C 1 149 ? 129.868 110.398 93.430  1.00 44.73  ? 95  ASP C CA  1 
ATOM   6282  C C   . ASP C 1 149 ? 130.126 109.841 94.822  1.00 44.18  ? 95  ASP C C   1 
ATOM   6283  O O   . ASP C 1 149 ? 129.189 109.534 95.565  1.00 40.95  ? 95  ASP C O   1 
ATOM   6284  C CB  . ASP C 1 149 ? 128.378 110.366 93.101  1.00 52.31  ? 95  ASP C CB  1 
ATOM   6285  C CG  . ASP C 1 149 ? 127.866 108.962 92.874  1.00 53.56  ? 95  ASP C CG  1 
ATOM   6286  O OD1 . ASP C 1 149 ? 128.686 108.078 92.549  1.00 49.59  ? 95  ASP C OD1 1 
ATOM   6287  O OD2 . ASP C 1 149 ? 126.648 108.743 93.020  1.00 53.08  ? 95  ASP C OD2 1 
ATOM   6288  N N   . THR C 1 150 ? 131.399 109.711 95.178  1.00 45.00  ? 96  THR C N   1 
ATOM   6289  C CA  . THR C 1 150 ? 131.768 109.168 96.474  1.00 39.28  ? 96  THR C CA  1 
ATOM   6290  C C   . THR C 1 150 ? 131.428 110.160 97.576  1.00 41.58  ? 96  THR C C   1 
ATOM   6291  O O   . THR C 1 150 ? 131.808 111.333 97.511  1.00 44.77  ? 96  THR C O   1 
ATOM   6292  C CB  . THR C 1 150 ? 133.259 108.844 96.496  1.00 38.34  ? 96  THR C CB  1 
ATOM   6293  O OG1 . THR C 1 150 ? 133.540 107.821 95.535  1.00 36.16  ? 96  THR C OG1 1 
ATOM   6294  C CG2 . THR C 1 150 ? 133.682 108.377 97.871  1.00 39.52  ? 96  THR C CG2 1 
ATOM   6295  N N   . TYR C 1 151 ? 130.716 109.687 98.593  1.00 37.34  ? 97  TYR C N   1 
ATOM   6296  C CA  . TYR C 1 151 ? 130.357 110.516 99.731  1.00 37.14  ? 97  TYR C CA  1 
ATOM   6297  C C   . TYR C 1 151 ? 130.527 109.700 101.001 1.00 37.77  ? 97  TYR C C   1 
ATOM   6298  O O   . TYR C 1 151 ? 130.505 108.468 100.980 1.00 42.03  ? 97  TYR C O   1 
ATOM   6299  C CB  . TYR C 1 151 ? 128.924 111.047 99.618  1.00 37.96  ? 97  TYR C CB  1 
ATOM   6300  C CG  . TYR C 1 151 ? 127.868 110.074 100.079 1.00 38.71  ? 97  TYR C CG  1 
ATOM   6301  C CD1 . TYR C 1 151 ? 127.533 108.969 99.315  1.00 40.50  ? 97  TYR C CD1 1 
ATOM   6302  C CD2 . TYR C 1 151 ? 127.199 110.266 101.276 1.00 38.82  ? 97  TYR C CD2 1 
ATOM   6303  C CE1 . TYR C 1 151 ? 126.567 108.080 99.734  1.00 36.45  ? 97  TYR C CE1 1 
ATOM   6304  C CE2 . TYR C 1 151 ? 126.233 109.383 101.701 1.00 40.94  ? 97  TYR C CE2 1 
ATOM   6305  C CZ  . TYR C 1 151 ? 125.921 108.293 100.926 1.00 37.50  ? 97  TYR C CZ  1 
ATOM   6306  O OH  . TYR C 1 151 ? 124.957 107.409 101.345 1.00 48.45  ? 97  TYR C OH  1 
ATOM   6307  N N   . PHE C 1 152 ? 130.705 110.404 102.113 1.00 36.33  ? 98  PHE C N   1 
ATOM   6308  C CA  . PHE C 1 152 ? 130.920 109.778 103.409 1.00 35.09  ? 98  PHE C CA  1 
ATOM   6309  C C   . PHE C 1 152 ? 129.588 109.692 104.139 1.00 38.54  ? 98  PHE C C   1 
ATOM   6310  O O   . PHE C 1 152 ? 128.918 110.709 104.341 1.00 41.68  ? 98  PHE C O   1 
ATOM   6311  C CB  . PHE C 1 152 ? 131.954 110.558 104.216 1.00 38.74  ? 98  PHE C CB  1 
ATOM   6312  C CG  . PHE C 1 152 ? 133.207 110.847 103.449 1.00 40.24  ? 98  PHE C CG  1 
ATOM   6313  C CD1 . PHE C 1 152 ? 134.141 109.851 103.225 1.00 35.77  ? 98  PHE C CD1 1 
ATOM   6314  C CD2 . PHE C 1 152 ? 133.443 112.106 102.932 1.00 41.86  ? 98  PHE C CD2 1 
ATOM   6315  C CE1 . PHE C 1 152 ? 135.289 110.110 102.511 1.00 32.78  ? 98  PHE C CE1 1 
ATOM   6316  C CE2 . PHE C 1 152 ? 134.589 112.370 102.217 1.00 41.96  ? 98  PHE C CE2 1 
ATOM   6317  C CZ  . PHE C 1 152 ? 135.512 111.371 102.005 1.00 37.07  ? 98  PHE C CZ  1 
ATOM   6318  N N   . LEU C 1 153 ? 129.210 108.476 104.533 1.00 41.68  ? 99  LEU C N   1 
ATOM   6319  C CA  . LEU C 1 153 ? 127.842 108.228 104.969 1.00 40.09  ? 99  LEU C CA  1 
ATOM   6320  C C   . LEU C 1 153 ? 127.554 108.819 106.345 1.00 45.72  ? 99  LEU C C   1 
ATOM   6321  O O   . LEU C 1 153 ? 126.410 109.193 106.625 1.00 51.54  ? 99  LEU C O   1 
ATOM   6322  C CB  . LEU C 1 153 ? 127.570 106.725 104.964 1.00 41.00  ? 99  LEU C CB  1 
ATOM   6323  C CG  . LEU C 1 153 ? 126.165 106.267 105.346 1.00 47.59  ? 99  LEU C CG  1 
ATOM   6324  C CD1 . LEU C 1 153 ? 125.542 105.473 104.215 1.00 50.45  ? 99  LEU C CD1 1 
ATOM   6325  C CD2 . LEU C 1 153 ? 126.209 105.443 106.618 1.00 52.74  ? 99  LEU C CD2 1 
ATOM   6326  N N   . ASN C 1 154 ? 128.564 108.923 107.209 1.00 46.25  ? 100 ASN C N   1 
ATOM   6327  C CA  . ASN C 1 154 ? 128.358 109.347 108.588 1.00 44.36  ? 100 ASN C CA  1 
ATOM   6328  C C   . ASN C 1 154 ? 128.950 110.722 108.881 1.00 49.84  ? 100 ASN C C   1 
ATOM   6329  O O   . ASN C 1 154 ? 129.243 111.029 110.040 1.00 53.68  ? 100 ASN C O   1 
ATOM   6330  C CB  . ASN C 1 154 ? 128.934 108.311 109.553 1.00 44.05  ? 100 ASN C CB  1 
ATOM   6331  C CG  . ASN C 1 154 ? 130.404 108.040 109.308 1.00 47.09  ? 100 ASN C CG  1 
ATOM   6332  O OD1 . ASN C 1 154 ? 130.854 107.982 108.164 1.00 48.22  ? 100 ASN C OD1 1 
ATOM   6333  N ND2 . ASN C 1 154 ? 131.163 107.874 110.384 1.00 47.50  ? 100 ASN C ND2 1 
ATOM   6334  N N   . ASP C 1 155 ? 129.126 111.557 107.863 1.00 49.33  ? 101 ASP C N   1 
ATOM   6335  C CA  . ASP C 1 155 ? 129.683 112.884 108.068 1.00 48.48  ? 101 ASP C CA  1 
ATOM   6336  C C   . ASP C 1 155 ? 128.579 113.894 108.363 1.00 49.20  ? 101 ASP C C   1 
ATOM   6337  O O   . ASP C 1 155 ? 127.405 113.684 108.048 1.00 48.76  ? 101 ASP C O   1 
ATOM   6338  C CB  . ASP C 1 155 ? 130.490 113.332 106.849 1.00 51.17  ? 101 ASP C CB  1 
ATOM   6339  C CG  . ASP C 1 155 ? 129.614 113.703 105.670 1.00 58.95  ? 101 ASP C CG  1 
ATOM   6340  O OD1 . ASP C 1 155 ? 128.516 113.126 105.534 1.00 61.51  ? 101 ASP C OD1 1 
ATOM   6341  O OD2 . ASP C 1 155 ? 130.022 114.575 104.874 1.00 61.22  ? 101 ASP C OD2 1 
ATOM   6342  N N   . LYS C 1 156 ? 128.974 115.002 108.982 1.00 49.67  ? 102 LYS C N   1 
ATOM   6343  C CA  . LYS C 1 156 ? 128.073 116.100 109.295 1.00 47.91  ? 102 LYS C CA  1 
ATOM   6344  C C   . LYS C 1 156 ? 128.450 117.373 108.559 1.00 55.25  ? 102 LYS C C   1 
ATOM   6345  O O   . LYS C 1 156 ? 127.598 117.981 107.901 1.00 60.97  ? 102 LYS C O   1 
ATOM   6346  C CB  . LYS C 1 156 ? 128.064 116.338 110.812 1.00 43.10  ? 102 LYS C CB  1 
ATOM   6347  C CG  . LYS C 1 156 ? 127.715 115.093 111.604 1.00 47.47  ? 102 LYS C CG  1 
ATOM   6348  C CD  . LYS C 1 156 ? 128.184 115.187 113.042 1.00 49.53  ? 102 LYS C CD  1 
ATOM   6349  C CE  . LYS C 1 156 ? 127.451 116.277 113.795 1.00 55.75  ? 102 LYS C CE  1 
ATOM   6350  N NZ  . LYS C 1 156 ? 127.896 116.337 115.212 1.00 63.52  ? 102 LYS C NZ  1 
ATOM   6351  N N   . LYS C 1 157 ? 129.709 117.793 108.652 1.00 54.80  ? 103 LYS C N   1 
ATOM   6352  C CA  . LYS C 1 157 ? 130.217 118.932 107.894 1.00 54.10  ? 103 LYS C CA  1 
ATOM   6353  C C   . LYS C 1 157 ? 131.564 118.539 107.307 1.00 55.94  ? 103 LYS C C   1 
ATOM   6354  O O   . LYS C 1 157 ? 132.520 118.296 108.050 1.00 59.24  ? 103 LYS C O   1 
ATOM   6355  C CB  . LYS C 1 157 ? 130.344 120.175 108.773 1.00 52.42  ? 103 LYS C CB  1 
ATOM   6356  C CG  . LYS C 1 157 ? 129.284 121.224 108.502 1.00 65.71  ? 103 LYS C CG  1 
ATOM   6357  C CD  . LYS C 1 157 ? 129.336 121.688 107.057 1.00 70.03  ? 103 LYS C CD  1 
ATOM   6358  C CE  . LYS C 1 157 ? 128.271 122.732 106.773 1.00 78.98  ? 103 LYS C CE  1 
ATOM   6359  N NZ  . LYS C 1 157 ? 128.309 123.196 105.360 1.00 78.42  ? 103 LYS C NZ  1 
ATOM   6360  N N   . SER C 1 158 ? 131.640 118.476 105.981 1.00 52.89  ? 104 SER C N   1 
ATOM   6361  C CA  . SER C 1 158 ? 132.868 118.130 105.285 1.00 51.62  ? 104 SER C CA  1 
ATOM   6362  C C   . SER C 1 158 ? 133.101 119.118 104.153 1.00 49.85  ? 104 SER C C   1 
ATOM   6363  O O   . SER C 1 158 ? 132.155 119.639 103.558 1.00 50.64  ? 104 SER C O   1 
ATOM   6364  C CB  . SER C 1 158 ? 132.819 116.700 104.736 1.00 53.10  ? 104 SER C CB  1 
ATOM   6365  O OG  . SER C 1 158 ? 131.674 116.505 103.927 1.00 60.57  ? 104 SER C OG  1 
ATOM   6366  N N   . PHE C 1 159 ? 134.374 119.372 103.860 1.00 44.70  ? 105 PHE C N   1 
ATOM   6367  C CA  . PHE C 1 159 ? 134.729 120.341 102.837 1.00 41.89  ? 105 PHE C CA  1 
ATOM   6368  C C   . PHE C 1 159 ? 136.102 120.008 102.274 1.00 40.71  ? 105 PHE C C   1 
ATOM   6369  O O   . PHE C 1 159 ? 136.921 119.351 102.921 1.00 45.81  ? 105 PHE C O   1 
ATOM   6370  C CB  . PHE C 1 159 ? 134.713 121.771 103.390 1.00 43.41  ? 105 PHE C CB  1 
ATOM   6371  C CG  . PHE C 1 159 ? 135.735 122.018 104.462 1.00 42.11  ? 105 PHE C CG  1 
ATOM   6372  C CD1 . PHE C 1 159 ? 135.475 121.681 105.778 1.00 40.66  ? 105 PHE C CD1 1 
ATOM   6373  C CD2 . PHE C 1 159 ? 136.954 122.595 104.153 1.00 40.79  ? 105 PHE C CD2 1 
ATOM   6374  C CE1 . PHE C 1 159 ? 136.413 121.910 106.764 1.00 40.25  ? 105 PHE C CE1 1 
ATOM   6375  C CE2 . PHE C 1 159 ? 137.895 122.825 105.133 1.00 39.24  ? 105 PHE C CE2 1 
ATOM   6376  C CZ  . PHE C 1 159 ? 137.625 122.484 106.440 1.00 39.03  ? 105 PHE C CZ  1 
ATOM   6377  N N   . VAL C 1 160 ? 136.338 120.470 101.050 1.00 35.85  ? 106 VAL C N   1 
ATOM   6378  C CA  . VAL C 1 160 ? 137.630 120.353 100.387 1.00 40.24  ? 106 VAL C CA  1 
ATOM   6379  C C   . VAL C 1 160 ? 138.323 121.704 100.462 1.00 45.70  ? 106 VAL C C   1 
ATOM   6380  O O   . VAL C 1 160 ? 137.730 122.732 100.114 1.00 51.23  ? 106 VAL C O   1 
ATOM   6381  C CB  . VAL C 1 160 ? 137.470 119.897 98.927  1.00 37.48  ? 106 VAL C CB  1 
ATOM   6382  C CG1 . VAL C 1 160 ? 138.830 119.688 98.282  1.00 37.93  ? 106 VAL C CG1 1 
ATOM   6383  C CG2 . VAL C 1 160 ? 136.638 118.630 98.860  1.00 34.47  ? 106 VAL C CG2 1 
ATOM   6384  N N   . HIS C 1 161 ? 139.570 121.708 100.922 1.00 38.74  ? 107 HIS C N   1 
ATOM   6385  C CA  . HIS C 1 161 ? 140.299 122.956 101.086 1.00 38.81  ? 107 HIS C CA  1 
ATOM   6386  C C   . HIS C 1 161 ? 140.536 123.625 99.736  1.00 41.67  ? 107 HIS C C   1 
ATOM   6387  O O   . HIS C 1 161 ? 140.751 122.963 98.718  1.00 45.89  ? 107 HIS C O   1 
ATOM   6388  C CB  . HIS C 1 161 ? 141.627 122.705 101.792 1.00 36.27  ? 107 HIS C CB  1 
ATOM   6389  C CG  . HIS C 1 161 ? 141.486 122.016 103.112 1.00 37.14  ? 107 HIS C CG  1 
ATOM   6390  N ND1 . HIS C 1 161 ? 141.481 122.697 104.310 1.00 41.85  ? 107 HIS C ND1 1 
ATOM   6391  C CD2 . HIS C 1 161 ? 141.342 120.707 103.424 1.00 38.29  ? 107 HIS C CD2 1 
ATOM   6392  C CE1 . HIS C 1 161 ? 141.343 121.837 105.303 1.00 40.30  ? 107 HIS C CE1 1 
ATOM   6393  N NE2 . HIS C 1 161 ? 141.255 120.623 104.792 1.00 38.65  ? 107 HIS C NE2 1 
ATOM   6394  N N   . GLY C 1 162 ? 140.495 124.956 99.737  1.00 39.56  ? 108 GLY C N   1 
ATOM   6395  C CA  . GLY C 1 162 ? 140.588 125.706 98.501  1.00 40.00  ? 108 GLY C CA  1 
ATOM   6396  C C   . GLY C 1 162 ? 141.576 126.854 98.511  1.00 41.37  ? 108 GLY C C   1 
ATOM   6397  O O   . GLY C 1 162 ? 141.324 127.892 97.895  1.00 47.60  ? 108 GLY C O   1 
ATOM   6398  N N   . VAL C 1 163 ? 142.700 126.688 99.203  1.00 39.86  ? 109 VAL C N   1 
ATOM   6399  C CA  . VAL C 1 163 ? 143.742 127.709 99.274  1.00 39.71  ? 109 VAL C CA  1 
ATOM   6400  C C   . VAL C 1 163 ? 145.090 127.031 99.071  1.00 40.03  ? 109 VAL C C   1 
ATOM   6401  O O   . VAL C 1 163 ? 145.386 126.031 99.733  1.00 42.95  ? 109 VAL C O   1 
ATOM   6402  C CB  . VAL C 1 163 ? 143.705 128.466 100.617 1.00 36.67  ? 109 VAL C CB  1 
ATOM   6403  C CG1 . VAL C 1 163 ? 144.905 129.379 100.757 1.00 35.51  ? 109 VAL C CG1 1 
ATOM   6404  C CG2 . VAL C 1 163 ? 142.421 129.265 100.739 1.00 38.97  ? 109 VAL C CG2 1 
ATOM   6405  N N   . THR C 1 164 ? 145.910 127.565 98.163  1.00 36.13  ? 110 THR C N   1 
ATOM   6406  C CA  . THR C 1 164 ? 145.588 128.748 97.365  1.00 37.23  ? 110 THR C CA  1 
ATOM   6407  C C   . THR C 1 164 ? 144.697 128.401 96.183  1.00 40.28  ? 110 THR C C   1 
ATOM   6408  O O   . THR C 1 164 ? 144.098 129.274 95.559  1.00 45.81  ? 110 THR C O   1 
ATOM   6409  C CB  . THR C 1 164 ? 146.860 129.430 96.840  1.00 37.57  ? 110 THR C CB  1 
ATOM   6410  O OG1 . THR C 1 164 ? 147.547 128.542 95.951  1.00 35.34  ? 110 THR C OG1 1 
ATOM   6411  C CG2 . THR C 1 164 ? 147.779 129.789 97.990  1.00 38.46  ? 110 THR C CG2 1 
ATOM   6412  N N   . VAL C 1 165 ? 144.629 127.108 95.879  1.00 40.45  ? 111 VAL C N   1 
ATOM   6413  C CA  . VAL C 1 165 ? 143.686 126.561 94.918  1.00 41.86  ? 111 VAL C CA  1 
ATOM   6414  C C   . VAL C 1 165 ? 142.935 125.437 95.613  1.00 43.84  ? 111 VAL C C   1 
ATOM   6415  O O   . VAL C 1 165 ? 143.289 125.015 96.713  1.00 46.45  ? 111 VAL C O   1 
ATOM   6416  C CB  . VAL C 1 165 ? 144.373 126.046 93.637  1.00 42.09  ? 111 VAL C CB  1 
ATOM   6417  C CG1 . VAL C 1 165 ? 145.248 127.128 93.031  1.00 44.31  ? 111 VAL C CG1 1 
ATOM   6418  C CG2 . VAL C 1 165 ? 145.185 124.800 93.941  1.00 39.66  ? 111 VAL C CG2 1 
ATOM   6419  N N   . LYS C 1 166 ? 141.880 124.957 94.962  1.00 43.14  ? 112 LYS C N   1 
ATOM   6420  C CA  . LYS C 1 166 ? 141.180 123.796 95.488  1.00 41.68  ? 112 LYS C CA  1 
ATOM   6421  C C   . LYS C 1 166 ? 142.134 122.614 95.551  1.00 44.34  ? 112 LYS C C   1 
ATOM   6422  O O   . LYS C 1 166 ? 142.739 122.236 94.544  1.00 49.41  ? 112 LYS C O   1 
ATOM   6423  C CB  . LYS C 1 166 ? 139.966 123.464 94.623  1.00 44.11  ? 112 LYS C CB  1 
ATOM   6424  C CG  . LYS C 1 166 ? 138.658 124.003 95.172  1.00 45.49  ? 112 LYS C CG  1 
ATOM   6425  C CD  . LYS C 1 166 ? 137.483 123.528 94.342  1.00 56.83  ? 112 LYS C CD  1 
ATOM   6426  C CE  . LYS C 1 166 ? 137.479 122.016 94.229  1.00 59.89  ? 112 LYS C CE  1 
ATOM   6427  N NZ  . LYS C 1 166 ? 137.478 121.369 95.567  1.00 54.08  ? 112 LYS C NZ  1 
ATOM   6428  N N   . ASN C 1 167 ? 142.269 122.032 96.742  1.00 41.11  ? 113 ASN C N   1 
ATOM   6429  C CA  . ASN C 1 167 ? 143.240 120.964 96.978  1.00 35.60  ? 113 ASN C CA  1 
ATOM   6430  C C   . ASN C 1 167 ? 142.757 119.720 96.244  1.00 38.65  ? 113 ASN C C   1 
ATOM   6431  O O   . ASN C 1 167 ? 142.207 118.781 96.821  1.00 42.56  ? 113 ASN C O   1 
ATOM   6432  C CB  . ASN C 1 167 ? 143.417 120.706 98.467  1.00 34.74  ? 113 ASN C CB  1 
ATOM   6433  C CG  . ASN C 1 167 ? 144.114 121.846 99.177  1.00 34.59  ? 113 ASN C CG  1 
ATOM   6434  O OD1 . ASN C 1 167 ? 144.309 121.806 100.390 1.00 34.44  ? 113 ASN C OD1 1 
ATOM   6435  N ND2 . ASN C 1 167 ? 144.493 122.872 98.425  1.00 35.51  ? 113 ASN C ND2 1 
ATOM   6436  N N   . ARG C 1 168 ? 142.977 119.725 94.933  1.00 40.77  ? 114 ARG C N   1 
ATOM   6437  C CA  . ARG C 1 168 ? 142.466 118.701 94.041  1.00 37.63  ? 114 ARG C CA  1 
ATOM   6438  C C   . ARG C 1 168 ? 143.540 118.363 93.022  1.00 39.64  ? 114 ARG C C   1 
ATOM   6439  O O   . ARG C 1 168 ? 144.245 119.249 92.537  1.00 49.63  ? 114 ARG C O   1 
ATOM   6440  C CB  . ARG C 1 168 ? 141.189 119.183 93.347  1.00 42.88  ? 114 ARG C CB  1 
ATOM   6441  C CG  . ARG C 1 168 ? 140.501 118.153 92.490  1.00 48.31  ? 114 ARG C CG  1 
ATOM   6442  C CD  . ARG C 1 168 ? 139.093 118.608 92.165  1.00 53.35  ? 114 ARG C CD  1 
ATOM   6443  N NE  . ARG C 1 168 ? 139.081 119.885 91.462  1.00 60.42  ? 114 ARG C NE  1 
ATOM   6444  C CZ  . ARG C 1 168 ? 137.981 120.546 91.133  1.00 66.86  ? 114 ARG C CZ  1 
ATOM   6445  N NH1 . ARG C 1 168 ? 136.780 120.087 91.443  1.00 68.60  ? 114 ARG C NH1 1 
ATOM   6446  N NH2 . ARG C 1 168 ? 138.088 121.699 90.478  1.00 64.34  ? 114 ARG C NH2 1 
ATOM   6447  N N   . MET C 1 169 ? 143.672 117.078 92.716  1.00 39.88  ? 115 MET C N   1 
ATOM   6448  C CA  . MET C 1 169 ? 144.697 116.595 91.803  1.00 41.42  ? 115 MET C CA  1 
ATOM   6449  C C   . MET C 1 169 ? 144.078 115.624 90.814  1.00 41.56  ? 115 MET C C   1 
ATOM   6450  O O   . MET C 1 169 ? 143.377 114.691 91.217  1.00 48.04  ? 115 MET C O   1 
ATOM   6451  C CB  . MET C 1 169 ? 145.834 115.912 92.562  1.00 46.83  ? 115 MET C CB  1 
ATOM   6452  C CG  . MET C 1 169 ? 146.840 115.217 91.668  1.00 51.86  ? 115 MET C CG  1 
ATOM   6453  S SD  . MET C 1 169 ? 147.755 113.939 92.544  1.00 85.13  ? 115 MET C SD  1 
ATOM   6454  C CE  . MET C 1 169 ? 146.423 112.833 92.996  1.00 53.65  ? 115 MET C CE  1 
ATOM   6455  N N   . ILE C 1 170 ? 144.342 115.842 89.529  1.00 41.95  ? 116 ILE C N   1 
ATOM   6456  C CA  . ILE C 1 170 ? 143.927 114.939 88.463  1.00 46.54  ? 116 ILE C CA  1 
ATOM   6457  C C   . ILE C 1 170 ? 145.168 114.488 87.709  1.00 47.98  ? 116 ILE C C   1 
ATOM   6458  O O   . ILE C 1 170 ? 145.963 115.318 87.248  1.00 55.88  ? 116 ILE C O   1 
ATOM   6459  C CB  . ILE C 1 170 ? 142.912 115.601 87.513  1.00 48.63  ? 116 ILE C CB  1 
ATOM   6460  C CG1 . ILE C 1 170 ? 141.494 115.429 88.053  1.00 51.65  ? 116 ILE C CG1 1 
ATOM   6461  C CG2 . ILE C 1 170 ? 143.003 114.997 86.124  1.00 46.76  ? 116 ILE C CG2 1 
ATOM   6462  C CD1 . ILE C 1 170 ? 141.015 113.994 88.033  1.00 48.03  ? 116 ILE C CD1 1 
ATOM   6463  N N   . ARG C 1 171 ? 145.343 113.174 87.600  1.00 44.31  ? 117 ARG C N   1 
ATOM   6464  C CA  . ARG C 1 171 ? 146.454 112.596 86.859  1.00 48.35  ? 117 ARG C CA  1 
ATOM   6465  C C   . ARG C 1 171 ? 145.917 111.555 85.891  1.00 52.84  ? 117 ARG C C   1 
ATOM   6466  O O   . ARG C 1 171 ? 145.205 110.632 86.299  1.00 59.18  ? 117 ARG C O   1 
ATOM   6467  C CB  . ARG C 1 171 ? 147.482 111.973 87.802  1.00 52.96  ? 117 ARG C CB  1 
ATOM   6468  C CG  . ARG C 1 171 ? 148.777 111.572 87.124  1.00 58.40  ? 117 ARG C CG  1 
ATOM   6469  C CD  . ARG C 1 171 ? 149.755 111.012 88.135  1.00 57.04  ? 117 ARG C CD  1 
ATOM   6470  N NE  . ARG C 1 171 ? 150.148 112.015 89.117  1.00 61.87  ? 117 ARG C NE  1 
ATOM   6471  C CZ  . ARG C 1 171 ? 150.712 111.738 90.284  1.00 66.31  ? 117 ARG C CZ  1 
ATOM   6472  N NH1 . ARG C 1 171 ? 150.939 110.492 90.664  1.00 64.77  ? 117 ARG C NH1 1 
ATOM   6473  N NH2 . ARG C 1 171 ? 151.054 112.737 91.092  1.00 60.92  ? 117 ARG C NH2 1 
ATOM   6474  N N   . LEU C 1 172 ? 146.260 111.709 84.618  1.00 53.44  ? 118 LEU C N   1 
ATOM   6475  C CA  . LEU C 1 172 ? 145.861 110.785 83.569  1.00 55.07  ? 118 LEU C CA  1 
ATOM   6476  C C   . LEU C 1 172 ? 147.036 109.901 83.175  1.00 64.57  ? 118 LEU C C   1 
ATOM   6477  O O   . LEU C 1 172 ? 148.199 110.305 83.255  1.00 69.43  ? 118 LEU C O   1 
ATOM   6478  C CB  . LEU C 1 172 ? 145.349 111.534 82.339  1.00 53.05  ? 118 LEU C CB  1 
ATOM   6479  C CG  . LEU C 1 172 ? 144.166 112.478 82.539  1.00 55.20  ? 118 LEU C CG  1 
ATOM   6480  C CD1 . LEU C 1 172 ? 143.711 113.035 81.202  1.00 56.09  ? 118 LEU C CD1 1 
ATOM   6481  C CD2 . LEU C 1 172 ? 143.029 111.760 83.239  1.00 56.80  ? 118 LEU C CD2 1 
ATOM   6482  N N   . HIS C 1 173 ? 146.715 108.696 82.730  1.00 64.66  ? 119 HIS C N   1 
ATOM   6483  C CA  . HIS C 1 173 ? 147.684 107.684 82.349  1.00 66.44  ? 119 HIS C CA  1 
ATOM   6484  C C   . HIS C 1 173 ? 147.406 107.247 80.920  1.00 70.35  ? 119 HIS C C   1 
ATOM   6485  O O   . HIS C 1 173 ? 146.279 107.381 80.432  1.00 73.14  ? 119 HIS C O   1 
ATOM   6486  C CB  . HIS C 1 173 ? 147.622 106.483 83.304  1.00 65.74  ? 119 HIS C CB  1 
ATOM   6487  C CG  . HIS C 1 173 ? 147.918 106.833 84.730  1.00 69.14  ? 119 HIS C CG  1 
ATOM   6488  N ND1 . HIS C 1 173 ? 147.083 107.624 85.490  1.00 63.55  ? 119 HIS C ND1 1 
ATOM   6489  C CD2 . HIS C 1 173 ? 148.960 106.510 85.530  1.00 73.74  ? 119 HIS C CD2 1 
ATOM   6490  C CE1 . HIS C 1 173 ? 147.596 107.768 86.699  1.00 61.66  ? 119 HIS C CE1 1 
ATOM   6491  N NE2 . HIS C 1 173 ? 148.735 107.102 86.750  1.00 71.38  ? 119 HIS C NE2 1 
ATOM   6492  N N   . PRO C 1 174 ? 148.420 106.734 80.215  1.00 71.33  ? 120 PRO C N   1 
ATOM   6493  C CA  . PRO C 1 174 ? 148.237 106.427 78.785  1.00 71.92  ? 120 PRO C CA  1 
ATOM   6494  C C   . PRO C 1 174 ? 147.115 105.445 78.494  1.00 69.79  ? 120 PRO C C   1 
ATOM   6495  O O   . PRO C 1 174 ? 146.489 105.538 77.431  1.00 72.48  ? 120 PRO C O   1 
ATOM   6496  C CB  . PRO C 1 174 ? 149.602 105.856 78.378  1.00 71.46  ? 120 PRO C CB  1 
ATOM   6497  C CG  . PRO C 1 174 ? 150.557 106.461 79.339  1.00 71.16  ? 120 PRO C CG  1 
ATOM   6498  C CD  . PRO C 1 174 ? 149.820 106.559 80.639  1.00 71.72  ? 120 PRO C CD  1 
ATOM   6499  N N   . ASP C 1 175 ? 146.836 104.510 79.399  1.00 68.79  ? 121 ASP C N   1 
ATOM   6500  C CA  . ASP C 1 175 ? 145.783 103.528 79.177  1.00 70.92  ? 121 ASP C CA  1 
ATOM   6501  C C   . ASP C 1 175 ? 144.395 104.052 79.520  1.00 70.99  ? 121 ASP C C   1 
ATOM   6502  O O   . ASP C 1 175 ? 143.416 103.316 79.354  1.00 69.52  ? 121 ASP C O   1 
ATOM   6503  C CB  . ASP C 1 175 ? 146.065 102.260 79.986  1.00 71.01  ? 121 ASP C CB  1 
ATOM   6504  C CG  . ASP C 1 175 ? 146.300 102.547 81.453  1.00 78.73  ? 121 ASP C CG  1 
ATOM   6505  O OD1 . ASP C 1 175 ? 147.075 103.476 81.760  1.00 82.80  ? 121 ASP C OD1 1 
ATOM   6506  O OD2 . ASP C 1 175 ? 145.707 101.847 82.300  1.00 79.14  ? 121 ASP C OD2 1 
ATOM   6507  N N   . GLY C 1 176 ? 144.284 105.293 79.987  1.00 70.47  ? 122 GLY C N   1 
ATOM   6508  C CA  . GLY C 1 176 ? 143.014 105.855 80.392  1.00 66.90  ? 122 GLY C CA  1 
ATOM   6509  C C   . GLY C 1 176 ? 142.773 105.862 81.884  1.00 61.66  ? 122 GLY C C   1 
ATOM   6510  O O   . GLY C 1 176 ? 141.696 106.287 82.317  1.00 59.77  ? 122 GLY C O   1 
ATOM   6511  N N   . THR C 1 177 ? 143.737 105.407 82.677  1.00 59.33  ? 123 THR C N   1 
ATOM   6512  C CA  . THR C 1 177 ? 143.592 105.404 84.125  1.00 54.04  ? 123 THR C CA  1 
ATOM   6513  C C   . THR C 1 177 ? 143.569 106.829 84.663  1.00 54.64  ? 123 THR C C   1 
ATOM   6514  O O   . THR C 1 177 ? 144.405 107.658 84.292  1.00 61.87  ? 123 THR C O   1 
ATOM   6515  C CB  . THR C 1 177 ? 144.734 104.612 84.758  1.00 56.76  ? 123 THR C CB  1 
ATOM   6516  O OG1 . THR C 1 177 ? 144.445 103.211 84.686  1.00 64.77  ? 123 THR C OG1 1 
ATOM   6517  C CG2 . THR C 1 177 ? 144.937 105.017 86.203  1.00 55.70  ? 123 THR C CG2 1 
ATOM   6518  N N   . VAL C 1 178 ? 142.609 107.112 85.539  1.00 48.93  ? 124 VAL C N   1 
ATOM   6519  C CA  . VAL C 1 178 ? 142.474 108.407 86.191  1.00 42.74  ? 124 VAL C CA  1 
ATOM   6520  C C   . VAL C 1 178 ? 142.749 108.233 87.676  1.00 44.31  ? 124 VAL C C   1 
ATOM   6521  O O   . VAL C 1 178 ? 142.168 107.350 88.327  1.00 55.87  ? 124 VAL C O   1 
ATOM   6522  C CB  . VAL C 1 178 ? 141.079 109.013 85.966  1.00 40.29  ? 124 VAL C CB  1 
ATOM   6523  C CG1 . VAL C 1 178 ? 140.993 110.386 86.610  1.00 44.93  ? 124 VAL C CG1 1 
ATOM   6524  C CG2 . VAL C 1 178 ? 140.770 109.095 84.488  1.00 43.62  ? 124 VAL C CG2 1 
ATOM   6525  N N   . LEU C 1 179 ? 143.637 109.073 88.205  1.00 42.43  ? 125 LEU C N   1 
ATOM   6526  C CA  . LEU C 1 179 ? 143.884 109.193 89.635  1.00 44.35  ? 125 LEU C CA  1 
ATOM   6527  C C   . LEU C 1 179 ? 143.394 110.565 90.076  1.00 45.15  ? 125 LEU C C   1 
ATOM   6528  O O   . LEU C 1 179 ? 143.829 111.587 89.533  1.00 52.49  ? 125 LEU C O   1 
ATOM   6529  C CB  . LEU C 1 179 ? 145.366 109.016 89.958  1.00 48.11  ? 125 LEU C CB  1 
ATOM   6530  C CG  . LEU C 1 179 ? 145.761 109.098 91.433  1.00 47.94  ? 125 LEU C CG  1 
ATOM   6531  C CD1 . LEU C 1 179 ? 145.141 107.957 92.221  1.00 47.59  ? 125 LEU C CD1 1 
ATOM   6532  C CD2 . LEU C 1 179 ? 147.272 109.094 91.582  1.00 51.90  ? 125 LEU C CD2 1 
ATOM   6533  N N   . TYR C 1 180 ? 142.495 110.585 91.056  1.00 38.39  ? 126 TYR C N   1 
ATOM   6534  C CA  . TYR C 1 180 ? 141.767 111.787 91.450  1.00 36.24  ? 126 TYR C CA  1 
ATOM   6535  C C   . TYR C 1 180 ? 141.873 111.934 92.960  1.00 36.00  ? 126 TYR C C   1 
ATOM   6536  O O   . TYR C 1 180 ? 141.302 111.134 93.703  1.00 42.30  ? 126 TYR C O   1 
ATOM   6537  C CB  . TYR C 1 180 ? 140.311 111.693 90.994  1.00 38.55  ? 126 TYR C CB  1 
ATOM   6538  C CG  . TYR C 1 180 ? 139.405 112.799 91.471  1.00 38.04  ? 126 TYR C CG  1 
ATOM   6539  C CD1 . TYR C 1 180 ? 139.753 114.128 91.310  1.00 36.20  ? 126 TYR C CD1 1 
ATOM   6540  C CD2 . TYR C 1 180 ? 138.178 112.510 92.051  1.00 41.92  ? 126 TYR C CD2 1 
ATOM   6541  C CE1 . TYR C 1 180 ? 138.920 115.136 91.732  1.00 40.60  ? 126 TYR C CE1 1 
ATOM   6542  C CE2 . TYR C 1 180 ? 137.337 113.514 92.475  1.00 46.88  ? 126 TYR C CE2 1 
ATOM   6543  C CZ  . TYR C 1 180 ? 137.713 114.825 92.313  1.00 47.05  ? 126 TYR C CZ  1 
ATOM   6544  O OH  . TYR C 1 180 ? 136.880 115.833 92.734  1.00 47.84  ? 126 TYR C OH  1 
ATOM   6545  N N   . GLY C 1 181 ? 142.595 112.946 93.412  1.00 32.41  ? 127 GLY C N   1 
ATOM   6546  C CA  . GLY C 1 181 ? 142.902 113.108 94.826  1.00 32.99  ? 127 GLY C CA  1 
ATOM   6547  C C   . GLY C 1 181 ? 142.343 114.400 95.386  1.00 33.69  ? 127 GLY C C   1 
ATOM   6548  O O   . GLY C 1 181 ? 142.411 115.445 94.739  1.00 45.47  ? 127 GLY C O   1 
ATOM   6549  N N   . LEU C 1 182 ? 141.787 114.318 96.593  1.00 27.28  ? 128 LEU C N   1 
ATOM   6550  C CA  . LEU C 1 182 ? 141.257 115.472 97.301  1.00 27.11  ? 128 LEU C CA  1 
ATOM   6551  C C   . LEU C 1 182 ? 141.881 115.545 98.685  1.00 33.78  ? 128 LEU C C   1 
ATOM   6552  O O   . LEU C 1 182 ? 142.400 114.557 99.204  1.00 42.70  ? 128 LEU C O   1 
ATOM   6553  C CB  . LEU C 1 182 ? 139.732 115.403 97.435  1.00 28.73  ? 128 LEU C CB  1 
ATOM   6554  C CG  . LEU C 1 182 ? 138.895 115.337 96.162  1.00 28.01  ? 128 LEU C CG  1 
ATOM   6555  C CD1 . LEU C 1 182 ? 137.480 114.941 96.511  1.00 22.42  ? 128 LEU C CD1 1 
ATOM   6556  C CD2 . LEU C 1 182 ? 138.908 116.676 95.458  1.00 32.91  ? 128 LEU C CD2 1 
ATOM   6557  N N   . ARG C 1 183 ? 141.831 116.732 99.282  1.00 29.56  ? 129 ARG C N   1 
ATOM   6558  C CA  . ARG C 1 183 ? 142.200 116.919 100.681 1.00 30.62  ? 129 ARG C CA  1 
ATOM   6559  C C   . ARG C 1 183 ? 140.945 117.349 101.425 1.00 34.32  ? 129 ARG C C   1 
ATOM   6560  O O   . ARG C 1 183 ? 140.505 118.496 101.302 1.00 39.69  ? 129 ARG C O   1 
ATOM   6561  C CB  . ARG C 1 183 ? 143.320 117.941 100.841 1.00 30.56  ? 129 ARG C CB  1 
ATOM   6562  C CG  . ARG C 1 183 ? 143.875 117.995 102.250 1.00 30.31  ? 129 ARG C CG  1 
ATOM   6563  C CD  . ARG C 1 183 ? 145.227 118.672 102.286 1.00 32.29  ? 129 ARG C CD  1 
ATOM   6564  N NE  . ARG C 1 183 ? 145.127 120.123 102.204 1.00 37.00  ? 129 ARG C NE  1 
ATOM   6565  C CZ  . ARG C 1 183 ? 145.135 120.929 103.256 1.00 39.90  ? 129 ARG C CZ  1 
ATOM   6566  N NH1 . ARG C 1 183 ? 145.217 120.456 104.488 1.00 37.85  ? 129 ARG C NH1 1 
ATOM   6567  N NH2 . ARG C 1 183 ? 145.064 122.243 103.066 1.00 42.15  ? 129 ARG C NH2 1 
ATOM   6568  N N   . ILE C 1 184 ? 140.375 116.428 102.194 1.00 35.31  ? 130 ILE C N   1 
ATOM   6569  C CA  . ILE C 1 184 ? 139.052 116.593 102.782 1.00 36.93  ? 130 ILE C CA  1 
ATOM   6570  C C   . ILE C 1 184 ? 139.188 116.659 104.295 1.00 38.23  ? 130 ILE C C   1 
ATOM   6571  O O   . ILE C 1 184 ? 139.877 115.830 104.901 1.00 45.23  ? 130 ILE C O   1 
ATOM   6572  C CB  . ILE C 1 184 ? 138.113 115.448 102.365 1.00 34.54  ? 130 ILE C CB  1 
ATOM   6573  C CG1 . ILE C 1 184 ? 138.072 115.326 100.843 1.00 27.45  ? 130 ILE C CG1 1 
ATOM   6574  C CG2 . ILE C 1 184 ? 136.718 115.670 102.922 1.00 38.69  ? 130 ILE C CG2 1 
ATOM   6575  C CD1 . ILE C 1 184 ? 137.243 114.170 100.351 1.00 31.29  ? 130 ILE C CD1 1 
ATOM   6576  N N   . THR C 1 185 ? 138.538 117.649 104.897 1.00 36.13  ? 131 THR C N   1 
ATOM   6577  C CA  . THR C 1 185 ? 138.370 117.731 106.341 1.00 42.58  ? 131 THR C CA  1 
ATOM   6578  C C   . THR C 1 185 ? 136.900 117.491 106.651 1.00 48.35  ? 131 THR C C   1 
ATOM   6579  O O   . THR C 1 185 ? 136.034 118.234 106.177 1.00 50.53  ? 131 THR C O   1 
ATOM   6580  C CB  . THR C 1 185 ? 138.827 119.086 106.878 1.00 45.01  ? 131 THR C CB  1 
ATOM   6581  O OG1 . THR C 1 185 ? 140.224 119.258 106.613 1.00 47.32  ? 131 THR C OG1 1 
ATOM   6582  C CG2 . THR C 1 185 ? 138.586 119.174 108.374 1.00 43.05  ? 131 THR C CG2 1 
ATOM   6583  N N   . THR C 1 186 ? 136.622 116.457 107.439 1.00 49.62  ? 132 THR C N   1 
ATOM   6584  C CA  . THR C 1 186 ? 135.259 116.017 107.693 1.00 52.20  ? 132 THR C CA  1 
ATOM   6585  C C   . THR C 1 186 ? 135.061 115.762 109.178 1.00 53.38  ? 132 THR C C   1 
ATOM   6586  O O   . THR C 1 186 ? 135.931 115.195 109.843 1.00 53.79  ? 132 THR C O   1 
ATOM   6587  C CB  . THR C 1 186 ? 134.929 114.744 106.895 1.00 54.01  ? 132 THR C CB  1 
ATOM   6588  O OG1 . THR C 1 186 ? 133.738 114.140 107.413 1.00 58.17  ? 132 THR C OG1 1 
ATOM   6589  C CG2 . THR C 1 186 ? 136.076 113.750 106.969 1.00 50.74  ? 132 THR C CG2 1 
ATOM   6590  N N   . THR C 1 187 ? 133.917 116.195 109.694 1.00 52.34  ? 133 THR C N   1 
ATOM   6591  C CA  . THR C 1 187 ? 133.507 115.896 111.059 1.00 52.41  ? 133 THR C CA  1 
ATOM   6592  C C   . THR C 1 187 ? 132.505 114.751 110.994 1.00 57.61  ? 133 THR C C   1 
ATOM   6593  O O   . THR C 1 187 ? 131.350 114.950 110.610 1.00 58.66  ? 133 THR C O   1 
ATOM   6594  C CB  . THR C 1 187 ? 132.906 117.127 111.733 1.00 52.85  ? 133 THR C CB  1 
ATOM   6595  O OG1 . THR C 1 187 ? 133.837 118.213 111.656 1.00 58.53  ? 133 THR C OG1 1 
ATOM   6596  C CG2 . THR C 1 187 ? 132.599 116.840 113.191 1.00 50.40  ? 133 THR C CG2 1 
ATOM   6597  N N   . ALA C 1 188 ? 132.942 113.557 111.377 1.00 56.91  ? 134 ALA C N   1 
ATOM   6598  C CA  . ALA C 1 188 ? 132.126 112.360 111.263 1.00 53.56  ? 134 ALA C CA  1 
ATOM   6599  C C   . ALA C 1 188 ? 131.599 111.959 112.631 1.00 52.72  ? 134 ALA C C   1 
ATOM   6600  O O   . ALA C 1 188 ? 132.342 111.954 113.616 1.00 56.91  ? 134 ALA C O   1 
ATOM   6601  C CB  . ALA C 1 188 ? 132.926 111.209 110.653 1.00 55.70  ? 134 ALA C CB  1 
ATOM   6602  N N   . ALA C 1 189 ? 130.313 111.625 112.686 1.00 50.19  ? 135 ALA C N   1 
ATOM   6603  C CA  . ALA C 1 189 ? 129.686 111.269 113.950 1.00 53.18  ? 135 ALA C CA  1 
ATOM   6604  C C   . ALA C 1 189 ? 130.158 109.897 114.410 1.00 56.99  ? 135 ALA C C   1 
ATOM   6605  O O   . ALA C 1 189 ? 130.190 108.943 113.628 1.00 57.69  ? 135 ALA C O   1 
ATOM   6606  C CB  . ALA C 1 189 ? 128.166 111.287 113.813 1.00 46.74  ? 135 ALA C CB  1 
ATOM   6607  N N   . CYS C 1 190 ? 130.526 109.800 115.688 1.00 61.27  ? 136 CYS C N   1 
ATOM   6608  C CA  . CYS C 1 190 ? 130.953 108.544 116.307 1.00 66.72  ? 136 CYS C CA  1 
ATOM   6609  C C   . CYS C 1 190 ? 130.182 108.389 117.615 1.00 72.34  ? 136 CYS C C   1 
ATOM   6610  O O   . CYS C 1 190 ? 130.633 108.841 118.670 1.00 72.82  ? 136 CYS C O   1 
ATOM   6611  C CB  . CYS C 1 190 ? 132.464 108.520 116.528 1.00 68.45  ? 136 CYS C CB  1 
ATOM   6612  S SG  . CYS C 1 190 ? 133.055 107.039 117.378 1.00 92.70  ? 136 CYS C SG  1 
ATOM   6613  N N   . MET C 1 191 ? 129.012 107.758 117.539 1.00 71.07  ? 137 MET C N   1 
ATOM   6614  C CA  . MET C 1 191 ? 128.222 107.501 118.734 1.00 71.42  ? 137 MET C CA  1 
ATOM   6615  C C   . MET C 1 191 ? 128.986 106.593 119.685 1.00 70.70  ? 137 MET C C   1 
ATOM   6616  O O   . MET C 1 191 ? 129.361 105.473 119.329 1.00 75.02  ? 137 MET C O   1 
ATOM   6617  C CB  . MET C 1 191 ? 126.882 106.871 118.355 1.00 76.50  ? 137 MET C CB  1 
ATOM   6618  C CG  . MET C 1 191 ? 125.898 107.845 117.731 1.00 85.05  ? 137 MET C CG  1 
ATOM   6619  S SD  . MET C 1 191 ? 125.428 109.168 118.862 1.00 108.83 ? 137 MET C SD  1 
ATOM   6620  C CE  . MET C 1 191 ? 124.787 108.224 120.242 1.00 88.33  ? 137 MET C CE  1 
ATOM   6621  N N   . MET C 1 192 ? 129.213 107.082 120.898 1.00 67.74  ? 138 MET C N   1 
ATOM   6622  C CA  . MET C 1 192 ? 130.069 106.414 121.864 1.00 67.85  ? 138 MET C CA  1 
ATOM   6623  C C   . MET C 1 192 ? 129.243 105.705 122.927 1.00 65.50  ? 138 MET C C   1 
ATOM   6624  O O   . MET C 1 192 ? 128.077 106.034 123.161 1.00 68.55  ? 138 MET C O   1 
ATOM   6625  C CB  . MET C 1 192 ? 131.016 107.409 122.539 1.00 66.17  ? 138 MET C CB  1 
ATOM   6626  C CG  . MET C 1 192 ? 131.929 108.143 121.580 1.00 72.32  ? 138 MET C CG  1 
ATOM   6627  S SD  . MET C 1 192 ? 133.101 109.200 122.442 1.00 93.38  ? 138 MET C SD  1 
ATOM   6628  C CE  . MET C 1 192 ? 133.855 110.049 121.062 1.00 70.09  ? 138 MET C CE  1 
ATOM   6629  N N   . ASP C 1 193 ? 129.870 104.724 123.569 1.00 65.08  ? 139 ASP C N   1 
ATOM   6630  C CA  . ASP C 1 193 ? 129.307 104.026 124.718 1.00 64.20  ? 139 ASP C CA  1 
ATOM   6631  C C   . ASP C 1 193 ? 130.183 104.365 125.917 1.00 63.23  ? 139 ASP C C   1 
ATOM   6632  O O   . ASP C 1 193 ? 131.341 103.940 125.984 1.00 66.28  ? 139 ASP C O   1 
ATOM   6633  C CB  . ASP C 1 193 ? 129.249 102.521 124.469 1.00 66.42  ? 139 ASP C CB  1 
ATOM   6634  C CG  . ASP C 1 193 ? 128.347 101.803 125.448 1.00 71.00  ? 139 ASP C CG  1 
ATOM   6635  O OD1 . ASP C 1 193 ? 127.762 102.474 126.323 1.00 70.59  ? 139 ASP C OD1 1 
ATOM   6636  O OD2 . ASP C 1 193 ? 128.219 100.566 125.340 1.00 73.82  ? 139 ASP C OD2 1 
ATOM   6637  N N   . LEU C 1 194 ? 129.633 105.131 126.857 1.00 58.78  ? 140 LEU C N   1 
ATOM   6638  C CA  . LEU C 1 194 ? 130.400 105.706 127.954 1.00 57.63  ? 140 LEU C CA  1 
ATOM   6639  C C   . LEU C 1 194 ? 130.114 105.023 129.286 1.00 54.70  ? 140 LEU C C   1 
ATOM   6640  O O   . LEU C 1 194 ? 130.344 105.605 130.348 1.00 54.72  ? 140 LEU C O   1 
ATOM   6641  C CB  . LEU C 1 194 ? 130.128 107.205 128.059 1.00 53.65  ? 140 LEU C CB  1 
ATOM   6642  C CG  . LEU C 1 194 ? 130.321 108.010 126.775 1.00 51.53  ? 140 LEU C CG  1 
ATOM   6643  C CD1 . LEU C 1 194 ? 129.963 109.466 127.002 1.00 50.00  ? 140 LEU C CD1 1 
ATOM   6644  C CD2 . LEU C 1 194 ? 131.749 107.878 126.282 1.00 52.39  ? 140 LEU C CD2 1 
ATOM   6645  N N   . ARG C 1 195 ? 129.606 103.791 129.250 1.00 53.41  ? 141 ARG C N   1 
ATOM   6646  C CA  . ARG C 1 195 ? 129.327 103.074 130.488 1.00 53.22  ? 141 ARG C CA  1 
ATOM   6647  C C   . ARG C 1 195 ? 130.588 102.710 131.258 1.00 53.90  ? 141 ARG C C   1 
ATOM   6648  O O   . ARG C 1 195 ? 130.487 102.328 132.428 1.00 60.60  ? 141 ARG C O   1 
ATOM   6649  C CB  . ARG C 1 195 ? 128.512 101.817 130.192 1.00 56.00  ? 141 ARG C CB  1 
ATOM   6650  C CG  . ARG C 1 195 ? 127.079 102.110 129.795 1.00 54.18  ? 141 ARG C CG  1 
ATOM   6651  C CD  . ARG C 1 195 ? 126.344 100.853 129.383 1.00 57.81  ? 141 ARG C CD  1 
ATOM   6652  N NE  . ARG C 1 195 ? 124.949 101.130 129.066 1.00 66.86  ? 141 ARG C NE  1 
ATOM   6653  C CZ  . ARG C 1 195 ? 124.525 101.594 127.899 1.00 74.99  ? 141 ARG C CZ  1 
ATOM   6654  N NH1 . ARG C 1 195 ? 125.366 101.852 126.911 1.00 79.08  ? 141 ARG C NH1 1 
ATOM   6655  N NH2 . ARG C 1 195 ? 123.224 101.804 127.718 1.00 73.93  ? 141 ARG C NH2 1 
ATOM   6656  N N   . ARG C 1 196 ? 131.764 102.817 130.639 1.00 50.27  ? 142 ARG C N   1 
ATOM   6657  C CA  . ARG C 1 196 ? 133.031 102.558 131.311 1.00 50.98  ? 142 ARG C CA  1 
ATOM   6658  C C   . ARG C 1 196 ? 133.957 103.768 131.260 1.00 53.66  ? 142 ARG C C   1 
ATOM   6659  O O   . ARG C 1 196 ? 135.170 103.625 131.432 1.00 58.44  ? 142 ARG C O   1 
ATOM   6660  C CB  . ARG C 1 196 ? 133.717 101.336 130.700 1.00 49.93  ? 142 ARG C CB  1 
ATOM   6661  C CG  . ARG C 1 196 ? 132.934 100.048 130.856 1.00 52.65  ? 142 ARG C CG  1 
ATOM   6662  C CD  . ARG C 1 196 ? 133.536 98.938  130.016 1.00 58.88  ? 142 ARG C CD  1 
ATOM   6663  N NE  . ARG C 1 196 ? 134.931 98.689  130.358 1.00 63.29  ? 142 ARG C NE  1 
ATOM   6664  C CZ  . ARG C 1 196 ? 135.339 97.753  131.203 1.00 68.96  ? 142 ARG C CZ  1 
ATOM   6665  N NH1 . ARG C 1 196 ? 134.481 96.957  131.820 1.00 69.79  ? 142 ARG C NH1 1 
ATOM   6666  N NH2 . ARG C 1 196 ? 136.641 97.609  131.433 1.00 70.58  ? 142 ARG C NH2 1 
ATOM   6667  N N   . TYR C 1 197 ? 133.406 104.952 131.021 1.00 52.83  ? 143 TYR C N   1 
ATOM   6668  C CA  . TYR C 1 197 ? 134.209 106.162 130.968 1.00 52.41  ? 143 TYR C CA  1 
ATOM   6669  C C   . TYR C 1 197 ? 134.822 106.443 132.338 1.00 55.86  ? 143 TYR C C   1 
ATOM   6670  O O   . TYR C 1 197 ? 134.143 106.306 133.359 1.00 60.31  ? 143 TYR C O   1 
ATOM   6671  C CB  . TYR C 1 197 ? 133.339 107.336 130.518 1.00 51.22  ? 143 TYR C CB  1 
ATOM   6672  C CG  . TYR C 1 197 ? 134.022 108.683 130.476 1.00 50.79  ? 143 TYR C CG  1 
ATOM   6673  C CD1 . TYR C 1 197 ? 134.039 109.509 131.589 1.00 50.29  ? 143 TYR C CD1 1 
ATOM   6674  C CD2 . TYR C 1 197 ? 134.623 109.142 129.316 1.00 56.51  ? 143 TYR C CD2 1 
ATOM   6675  C CE1 . TYR C 1 197 ? 134.652 110.743 131.553 1.00 55.01  ? 143 TYR C CE1 1 
ATOM   6676  C CE2 . TYR C 1 197 ? 135.236 110.377 129.271 1.00 59.77  ? 143 TYR C CE2 1 
ATOM   6677  C CZ  . TYR C 1 197 ? 135.246 111.172 130.392 1.00 57.60  ? 143 TYR C CZ  1 
ATOM   6678  O OH  . TYR C 1 197 ? 135.854 112.404 130.355 1.00 65.75  ? 143 TYR C OH  1 
ATOM   6679  N N   . PRO C 1 198 ? 136.096 106.856 132.398 1.00 52.68  ? 144 PRO C N   1 
ATOM   6680  C CA  . PRO C 1 198 ? 137.015 107.155 131.300 1.00 49.44  ? 144 PRO C CA  1 
ATOM   6681  C C   . PRO C 1 198 ? 137.865 105.961 130.892 1.00 50.07  ? 144 PRO C C   1 
ATOM   6682  O O   . PRO C 1 198 ? 138.775 106.098 130.082 1.00 58.78  ? 144 PRO C O   1 
ATOM   6683  C CB  . PRO C 1 198 ? 137.870 108.272 131.894 1.00 50.28  ? 144 PRO C CB  1 
ATOM   6684  C CG  . PRO C 1 198 ? 138.028 107.839 133.328 1.00 49.81  ? 144 PRO C CG  1 
ATOM   6685  C CD  . PRO C 1 198 ? 136.730 107.137 133.698 1.00 54.84  ? 144 PRO C CD  1 
ATOM   6686  N N   . LEU C 1 199 ? 137.603 104.776 131.436 1.00 47.35  ? 145 LEU C N   1 
ATOM   6687  C CA  . LEU C 1 199 ? 138.314 103.569 131.037 1.00 46.30  ? 145 LEU C CA  1 
ATOM   6688  C C   . LEU C 1 199 ? 137.728 102.941 129.785 1.00 51.12  ? 145 LEU C C   1 
ATOM   6689  O O   . LEU C 1 199 ? 137.941 101.749 129.536 1.00 48.28  ? 145 LEU C O   1 
ATOM   6690  C CB  . LEU C 1 199 ? 138.306 102.553 132.181 1.00 46.32  ? 145 LEU C CB  1 
ATOM   6691  C CG  . LEU C 1 199 ? 138.973 102.982 133.486 1.00 53.35  ? 145 LEU C CG  1 
ATOM   6692  C CD1 . LEU C 1 199 ? 138.529 102.083 134.625 1.00 58.31  ? 145 LEU C CD1 1 
ATOM   6693  C CD2 . LEU C 1 199 ? 140.482 102.943 133.340 1.00 55.21  ? 145 LEU C CD2 1 
ATOM   6694  N N   . ASP C 1 200 ? 136.991 103.721 129.002 1.00 56.40  ? 146 ASP C N   1 
ATOM   6695  C CA  . ASP C 1 200 ? 136.271 103.220 127.846 1.00 56.43  ? 146 ASP C CA  1 
ATOM   6696  C C   . ASP C 1 200 ? 137.219 102.994 126.672 1.00 55.77  ? 146 ASP C C   1 
ATOM   6697  O O   . ASP C 1 200 ? 138.377 103.417 126.673 1.00 55.86  ? 146 ASP C O   1 
ATOM   6698  C CB  . ASP C 1 200 ? 135.164 104.195 127.452 1.00 54.20  ? 146 ASP C CB  1 
ATOM   6699  C CG  . ASP C 1 200 ? 135.687 105.596 127.206 1.00 57.72  ? 146 ASP C CG  1 
ATOM   6700  O OD1 . ASP C 1 200 ? 136.782 105.919 127.711 1.00 59.28  ? 146 ASP C OD1 1 
ATOM   6701  O OD2 . ASP C 1 200 ? 135.004 106.376 126.512 1.00 60.33  ? 146 ASP C OD2 1 
ATOM   6702  N N   . GLU C 1 201 ? 136.700 102.313 125.653 1.00 57.83  ? 147 GLU C N   1 
ATOM   6703  C CA  . GLU C 1 201 ? 137.443 102.048 124.426 1.00 55.88  ? 147 GLU C CA  1 
ATOM   6704  C C   . GLU C 1 201 ? 136.467 102.189 123.268 1.00 55.58  ? 147 GLU C C   1 
ATOM   6705  O O   . GLU C 1 201 ? 135.626 101.312 123.051 1.00 60.65  ? 147 GLU C O   1 
ATOM   6706  C CB  . GLU C 1 201 ? 138.077 100.660 124.450 1.00 58.87  ? 147 GLU C CB  1 
ATOM   6707  C CG  . GLU C 1 201 ? 139.196 100.476 123.452 1.00 63.52  ? 147 GLU C CG  1 
ATOM   6708  C CD  . GLU C 1 201 ? 139.902 99.150  123.623 1.00 77.35  ? 147 GLU C CD  1 
ATOM   6709  O OE1 . GLU C 1 201 ? 139.341 98.263  124.298 1.00 81.81  ? 147 GLU C OE1 1 
ATOM   6710  O OE2 . GLU C 1 201 ? 141.020 98.997  123.089 1.00 82.75  ? 147 GLU C OE2 1 
ATOM   6711  N N   . GLN C 1 202 ? 136.582 103.285 122.529 1.00 51.41  ? 148 GLN C N   1 
ATOM   6712  C CA  . GLN C 1 202 ? 135.612 103.620 121.500 1.00 53.76  ? 148 GLN C CA  1 
ATOM   6713  C C   . GLN C 1 202 ? 136.016 103.029 120.154 1.00 56.71  ? 148 GLN C C   1 
ATOM   6714  O O   . GLN C 1 202 ? 137.187 102.756 119.893 1.00 59.73  ? 148 GLN C O   1 
ATOM   6715  C CB  . GLN C 1 202 ? 135.458 105.136 121.383 1.00 55.76  ? 148 GLN C CB  1 
ATOM   6716  C CG  . GLN C 1 202 ? 135.164 105.835 122.700 1.00 56.37  ? 148 GLN C CG  1 
ATOM   6717  C CD  . GLN C 1 202 ? 133.881 105.353 123.348 1.00 61.85  ? 148 GLN C CD  1 
ATOM   6718  O OE1 . GLN C 1 202 ? 132.975 104.864 122.674 1.00 67.56  ? 148 GLN C OE1 1 
ATOM   6719  N NE2 . GLN C 1 202 ? 133.800 105.487 124.665 1.00 63.07  ? 148 GLN C NE2 1 
ATOM   6720  N N   . ASN C 1 203 ? 135.018 102.838 119.295 1.00 58.69  ? 149 ASN C N   1 
ATOM   6721  C CA  . ASN C 1 203 ? 135.208 102.300 117.948 1.00 56.05  ? 149 ASN C CA  1 
ATOM   6722  C C   . ASN C 1 203 ? 134.578 103.290 116.972 1.00 58.06  ? 149 ASN C C   1 
ATOM   6723  O O   . ASN C 1 203 ? 133.360 103.285 116.774 1.00 66.58  ? 149 ASN C O   1 
ATOM   6724  C CB  . ASN C 1 203 ? 134.594 100.905 117.830 1.00 62.70  ? 149 ASN C CB  1 
ATOM   6725  C CG  . ASN C 1 203 ? 134.598 100.368 116.406 1.00 67.73  ? 149 ASN C CG  1 
ATOM   6726  O OD1 . ASN C 1 203 ? 135.315 100.861 115.537 1.00 65.39  ? 149 ASN C OD1 1 
ATOM   6727  N ND2 . ASN C 1 203 ? 133.792 99.336  116.170 1.00 73.66  ? 149 ASN C ND2 1 
ATOM   6728  N N   . CYS C 1 204 ? 135.407 104.135 116.365 1.00 56.64  ? 150 CYS C N   1 
ATOM   6729  C CA  . CYS C 1 204 ? 134.933 105.187 115.473 1.00 58.12  ? 150 CYS C CA  1 
ATOM   6730  C C   . CYS C 1 204 ? 135.217 104.809 114.026 1.00 58.57  ? 150 CYS C C   1 
ATOM   6731  O O   . CYS C 1 204 ? 136.352 104.469 113.679 1.00 63.35  ? 150 CYS C O   1 
ATOM   6732  C CB  . CYS C 1 204 ? 135.588 106.527 115.808 1.00 62.98  ? 150 CYS C CB  1 
ATOM   6733  S SG  . CYS C 1 204 ? 135.078 107.224 117.394 1.00 88.98  ? 150 CYS C SG  1 
ATOM   6734  N N   . THR C 1 205 ? 134.193 104.884 113.182 1.00 56.24  ? 151 THR C N   1 
ATOM   6735  C CA  . THR C 1 205 ? 134.292 104.434 111.803 1.00 49.62  ? 151 THR C CA  1 
ATOM   6736  C C   . THR C 1 205 ? 134.025 105.577 110.834 1.00 49.49  ? 151 THR C C   1 
ATOM   6737  O O   . THR C 1 205 ? 133.307 106.531 111.148 1.00 53.93  ? 151 THR C O   1 
ATOM   6738  C CB  . THR C 1 205 ? 133.304 103.300 111.515 1.00 48.50  ? 151 THR C CB  1 
ATOM   6739  O OG1 . THR C 1 205 ? 131.966 103.800 111.610 1.00 53.36  ? 151 THR C OG1 1 
ATOM   6740  C CG2 . THR C 1 205 ? 133.488 102.169 112.509 1.00 54.88  ? 151 THR C CG2 1 
ATOM   6741  N N   . LEU C 1 206 ? 134.613 105.460 109.648 1.00 48.06  ? 152 LEU C N   1 
ATOM   6742  C CA  . LEU C 1 206 ? 134.335 106.334 108.518 1.00 45.42  ? 152 LEU C CA  1 
ATOM   6743  C C   . LEU C 1 206 ? 133.775 105.472 107.397 1.00 44.84  ? 152 LEU C C   1 
ATOM   6744  O O   . LEU C 1 206 ? 134.445 104.542 106.932 1.00 48.08  ? 152 LEU C O   1 
ATOM   6745  C CB  . LEU C 1 206 ? 135.594 107.073 108.060 1.00 45.06  ? 152 LEU C CB  1 
ATOM   6746  C CG  . LEU C 1 206 ? 135.459 107.942 106.809 1.00 47.05  ? 152 LEU C CG  1 
ATOM   6747  C CD1 . LEU C 1 206 ? 134.404 109.019 107.004 1.00 47.12  ? 152 LEU C CD1 1 
ATOM   6748  C CD2 . LEU C 1 206 ? 136.797 108.565 106.451 1.00 45.47  ? 152 LEU C CD2 1 
ATOM   6749  N N   . GLU C 1 207 ? 132.550 105.773 106.981 1.00 39.32  ? 153 GLU C N   1 
ATOM   6750  C CA  . GLU C 1 207 ? 131.832 104.991 105.987 1.00 38.17  ? 153 GLU C CA  1 
ATOM   6751  C C   . GLU C 1 207 ? 131.873 105.713 104.648 1.00 42.40  ? 153 GLU C C   1 
ATOM   6752  O O   . GLU C 1 207 ? 131.605 106.915 104.577 1.00 50.05  ? 153 GLU C O   1 
ATOM   6753  C CB  . GLU C 1 207 ? 130.386 104.764 106.424 1.00 43.56  ? 153 GLU C CB  1 
ATOM   6754  C CG  . GLU C 1 207 ? 130.249 104.048 107.755 1.00 45.57  ? 153 GLU C CG  1 
ATOM   6755  C CD  . GLU C 1 207 ? 130.600 102.579 107.659 1.00 57.61  ? 153 GLU C CD  1 
ATOM   6756  O OE1 . GLU C 1 207 ? 130.266 101.956 106.630 1.00 56.79  ? 153 GLU C OE1 1 
ATOM   6757  O OE2 . GLU C 1 207 ? 131.214 102.047 108.608 1.00 64.63  ? 153 GLU C OE2 1 
ATOM   6758  N N   . ILE C 1 208 ? 132.207 104.977 103.593 1.00 38.77  ? 154 ILE C N   1 
ATOM   6759  C CA  . ILE C 1 208 ? 132.375 105.519 102.252 1.00 41.08  ? 154 ILE C CA  1 
ATOM   6760  C C   . ILE C 1 208 ? 131.441 104.766 101.319 1.00 44.13  ? 154 ILE C C   1 
ATOM   6761  O O   . ILE C 1 208 ? 131.434 103.531 101.307 1.00 51.30  ? 154 ILE C O   1 
ATOM   6762  C CB  . ILE C 1 208 ? 133.834 105.401 101.781 1.00 39.30  ? 154 ILE C CB  1 
ATOM   6763  C CG1 . ILE C 1 208 ? 134.751 106.209 102.699 1.00 41.19  ? 154 ILE C CG1 1 
ATOM   6764  C CG2 . ILE C 1 208 ? 133.966 105.852 100.345 1.00 36.04  ? 154 ILE C CG2 1 
ATOM   6765  C CD1 . ILE C 1 208 ? 136.215 105.964 102.464 1.00 40.28  ? 154 ILE C CD1 1 
ATOM   6766  N N   . GLU C 1 209 ? 130.656 105.505 100.541 1.00 40.18  ? 155 GLU C N   1 
ATOM   6767  C CA  . GLU C 1 209 ? 129.638 104.883 99.710  1.00 40.86  ? 155 GLU C CA  1 
ATOM   6768  C C   . GLU C 1 209 ? 129.401 105.732 98.470  1.00 42.76  ? 155 GLU C C   1 
ATOM   6769  O O   . GLU C 1 209 ? 129.692 106.929 98.447  1.00 47.63  ? 155 GLU C O   1 
ATOM   6770  C CB  . GLU C 1 209 ? 128.339 104.692 100.501 1.00 43.59  ? 155 GLU C CB  1 
ATOM   6771  C CG  . GLU C 1 209 ? 127.267 103.893 99.790  1.00 47.30  ? 155 GLU C CG  1 
ATOM   6772  C CD  . GLU C 1 209 ? 126.120 103.536 100.702 1.00 59.35  ? 155 GLU C CD  1 
ATOM   6773  O OE1 . GLU C 1 209 ? 126.374 103.278 101.897 1.00 65.69  ? 155 GLU C OE1 1 
ATOM   6774  O OE2 . GLU C 1 209 ? 124.967 103.520 100.229 1.00 63.93  ? 155 GLU C OE2 1 
ATOM   6775  N N   . SER C 1 210 ? 128.879 105.087 97.431  1.00 40.31  ? 156 SER C N   1 
ATOM   6776  C CA  . SER C 1 210 ? 128.443 105.771 96.223  1.00 42.02  ? 156 SER C CA  1 
ATOM   6777  C C   . SER C 1 210 ? 126.984 106.176 96.372  1.00 47.67  ? 156 SER C C   1 
ATOM   6778  O O   . SER C 1 210 ? 126.129 105.338 96.675  1.00 52.44  ? 156 SER C O   1 
ATOM   6779  C CB  . SER C 1 210 ? 128.621 104.874 94.999  1.00 44.60  ? 156 SER C CB  1 
ATOM   6780  O OG  . SER C 1 210 ? 127.865 105.359 93.905  1.00 48.65  ? 156 SER C OG  1 
ATOM   6781  N N   . TYR C 1 211 ? 126.704 107.463 96.163  1.00 45.04  ? 157 TYR C N   1 
ATOM   6782  C CA  . TYR C 1 211 ? 125.359 107.969 96.411  1.00 42.95  ? 157 TYR C CA  1 
ATOM   6783  C C   . TYR C 1 211 ? 124.373 107.505 95.345  1.00 46.54  ? 157 TYR C C   1 
ATOM   6784  O O   . TYR C 1 211 ? 123.265 107.064 95.669  1.00 51.88  ? 157 TYR C O   1 
ATOM   6785  C CB  . TYR C 1 211 ? 125.381 109.494 96.490  1.00 40.82  ? 157 TYR C CB  1 
ATOM   6786  C CG  . TYR C 1 211 ? 124.112 110.080 97.056  1.00 42.51  ? 157 TYR C CG  1 
ATOM   6787  C CD1 . TYR C 1 211 ? 123.050 110.413 96.231  1.00 42.35  ? 157 TYR C CD1 1 
ATOM   6788  C CD2 . TYR C 1 211 ? 123.972 110.287 98.419  1.00 46.87  ? 157 TYR C CD2 1 
ATOM   6789  C CE1 . TYR C 1 211 ? 121.888 110.940 96.746  1.00 45.29  ? 157 TYR C CE1 1 
ATOM   6790  C CE2 . TYR C 1 211 ? 122.814 110.813 98.941  1.00 44.82  ? 157 TYR C CE2 1 
ATOM   6791  C CZ  . TYR C 1 211 ? 121.776 111.138 98.101  1.00 48.20  ? 157 TYR C CZ  1 
ATOM   6792  O OH  . TYR C 1 211 ? 120.620 111.662 98.620  1.00 65.24  ? 157 TYR C OH  1 
ATOM   6793  N N   . GLY C 1 212 ? 124.751 107.596 94.073  1.00 44.75  ? 158 GLY C N   1 
ATOM   6794  C CA  . GLY C 1 212 ? 123.813 107.340 92.998  1.00 45.51  ? 158 GLY C CA  1 
ATOM   6795  C C   . GLY C 1 212 ? 123.886 105.970 92.358  1.00 48.51  ? 158 GLY C C   1 
ATOM   6796  O O   . GLY C 1 212 ? 122.854 105.329 92.137  1.00 52.86  ? 158 GLY C O   1 
ATOM   6797  N N   . TYR C 1 213 ? 125.093 105.509 92.046  1.00 45.60  ? 159 TYR C N   1 
ATOM   6798  C CA  . TYR C 1 213 ? 125.257 104.272 91.297  1.00 44.87  ? 159 TYR C CA  1 
ATOM   6799  C C   . TYR C 1 213 ? 125.211 103.064 92.221  1.00 49.01  ? 159 TYR C C   1 
ATOM   6800  O O   . TYR C 1 213 ? 125.835 103.052 93.284  1.00 52.28  ? 159 TYR C O   1 
ATOM   6801  C CB  . TYR C 1 213 ? 126.578 104.280 90.531  1.00 47.80  ? 159 TYR C CB  1 
ATOM   6802  C CG  . TYR C 1 213 ? 126.776 105.488 89.651  1.00 46.91  ? 159 TYR C CG  1 
ATOM   6803  C CD1 . TYR C 1 213 ? 126.246 105.532 88.371  1.00 47.74  ? 159 TYR C CD1 1 
ATOM   6804  C CD2 . TYR C 1 213 ? 127.501 106.581 90.097  1.00 47.86  ? 159 TYR C CD2 1 
ATOM   6805  C CE1 . TYR C 1 213 ? 126.428 106.633 87.563  1.00 48.05  ? 159 TYR C CE1 1 
ATOM   6806  C CE2 . TYR C 1 213 ? 127.689 107.687 89.296  1.00 48.50  ? 159 TYR C CE2 1 
ATOM   6807  C CZ  . TYR C 1 213 ? 127.150 107.708 88.030  1.00 50.63  ? 159 TYR C CZ  1 
ATOM   6808  O OH  . TYR C 1 213 ? 127.334 108.807 87.227  1.00 58.85  ? 159 TYR C OH  1 
ATOM   6809  N N   . THR C 1 214 ? 124.469 102.043 91.802  1.00 51.94  ? 160 THR C N   1 
ATOM   6810  C CA  . THR C 1 214 ? 124.411 100.792 92.538  1.00 56.11  ? 160 THR C CA  1 
ATOM   6811  C C   . THR C 1 214 ? 125.617 99.924  92.184  1.00 56.03  ? 160 THR C C   1 
ATOM   6812  O O   . THR C 1 214 ? 126.494 100.315 91.409  1.00 57.35  ? 160 THR C O   1 
ATOM   6813  C CB  . THR C 1 214 ? 123.104 100.062 92.245  1.00 57.78  ? 160 THR C CB  1 
ATOM   6814  O OG1 . THR C 1 214 ? 123.028 99.752  90.848  1.00 63.16  ? 160 THR C OG1 1 
ATOM   6815  C CG2 . THR C 1 214 ? 121.916 100.925 92.631  1.00 58.66  ? 160 THR C CG2 1 
ATOM   6816  N N   . THR C 1 215 ? 125.664 98.722  92.761  1.00 58.00  ? 161 THR C N   1 
ATOM   6817  C CA  . THR C 1 215 ? 126.742 97.793  92.450  1.00 58.32  ? 161 THR C CA  1 
ATOM   6818  C C   . THR C 1 215 ? 126.702 97.308  91.008  1.00 64.07  ? 161 THR C C   1 
ATOM   6819  O O   . THR C 1 215 ? 127.703 96.765  90.529  1.00 69.93  ? 161 THR C O   1 
ATOM   6820  C CB  . THR C 1 215 ? 126.699 96.592  93.393  1.00 65.08  ? 161 THR C CB  1 
ATOM   6821  O OG1 . THR C 1 215 ? 125.379 96.035  93.403  1.00 72.53  ? 161 THR C OG1 1 
ATOM   6822  C CG2 . THR C 1 215 ? 127.083 97.009  94.802  1.00 60.95  ? 161 THR C CG2 1 
ATOM   6823  N N   . ASP C 1 216 ? 125.579 97.483  90.311  1.00 64.10  ? 162 ASP C N   1 
ATOM   6824  C CA  . ASP C 1 216 ? 125.526 97.168  88.890  1.00 65.14  ? 162 ASP C CA  1 
ATOM   6825  C C   . ASP C 1 216 ? 126.255 98.197  88.039  1.00 66.17  ? 162 ASP C C   1 
ATOM   6826  O O   . ASP C 1 216 ? 126.477 97.947  86.850  1.00 73.11  ? 162 ASP C O   1 
ATOM   6827  C CB  . ASP C 1 216 ? 124.072 97.058  88.429  1.00 69.53  ? 162 ASP C CB  1 
ATOM   6828  C CG  . ASP C 1 216 ? 123.224 96.218  89.364  1.00 77.76  ? 162 ASP C CG  1 
ATOM   6829  O OD1 . ASP C 1 216 ? 123.778 95.316  90.026  1.00 81.94  ? 162 ASP C OD1 1 
ATOM   6830  O OD2 . ASP C 1 216 ? 122.001 96.461  89.437  1.00 78.70  ? 162 ASP C OD2 1 
ATOM   6831  N N   . ASP C 1 217 ? 126.630 99.342  88.612  1.00 64.75  ? 163 ASP C N   1 
ATOM   6832  C CA  . ASP C 1 217 ? 127.312 100.395 87.877  1.00 64.32  ? 163 ASP C CA  1 
ATOM   6833  C C   . ASP C 1 217 ? 128.660 100.791 88.457  1.00 60.79  ? 163 ASP C C   1 
ATOM   6834  O O   . ASP C 1 217 ? 129.448 101.422 87.746  1.00 62.30  ? 163 ASP C O   1 
ATOM   6835  C CB  . ASP C 1 217 ? 126.431 101.652 87.795  1.00 63.62  ? 163 ASP C CB  1 
ATOM   6836  C CG  . ASP C 1 217 ? 125.236 101.467 86.884  1.00 74.64  ? 163 ASP C CG  1 
ATOM   6837  O OD1 . ASP C 1 217 ? 125.390 100.825 85.825  1.00 75.55  ? 163 ASP C OD1 1 
ATOM   6838  O OD2 . ASP C 1 217 ? 124.142 101.961 87.227  1.00 78.99  ? 163 ASP C OD2 1 
ATOM   6839  N N   . ILE C 1 218 ? 128.950 100.448 89.710  1.00 56.54  ? 164 ILE C N   1 
ATOM   6840  C CA  . ILE C 1 218 ? 130.201 100.850 90.339  1.00 50.39  ? 164 ILE C CA  1 
ATOM   6841  C C   . ILE C 1 218 ? 130.546 99.846  91.428  1.00 52.99  ? 164 ILE C C   1 
ATOM   6842  O O   . ILE C 1 218 ? 129.664 99.257  92.058  1.00 57.01  ? 164 ILE C O   1 
ATOM   6843  C CB  . ILE C 1 218 ? 130.110 102.290 90.899  1.00 45.78  ? 164 ILE C CB  1 
ATOM   6844  C CG1 . ILE C 1 218 ? 131.498 102.827 91.249  1.00 49.46  ? 164 ILE C CG1 1 
ATOM   6845  C CG2 . ILE C 1 218 ? 129.193 102.341 92.109  1.00 49.81  ? 164 ILE C CG2 1 
ATOM   6846  C CD1 . ILE C 1 218 ? 131.494 104.275 91.679  1.00 49.14  ? 164 ILE C CD1 1 
ATOM   6847  N N   . GLU C 1 219 ? 131.844 99.632  91.628  1.00 50.34  ? 165 GLU C N   1 
ATOM   6848  C CA  . GLU C 1 219 ? 132.338 98.757  92.679  1.00 51.78  ? 165 GLU C CA  1 
ATOM   6849  C C   . GLU C 1 219 ? 133.488 99.442  93.398  1.00 51.50  ? 165 GLU C C   1 
ATOM   6850  O O   . GLU C 1 219 ? 134.261 100.181 92.783  1.00 53.72  ? 165 GLU C O   1 
ATOM   6851  C CB  . GLU C 1 219 ? 132.802 97.407  92.123  1.00 53.25  ? 165 GLU C CB  1 
ATOM   6852  C CG  . GLU C 1 219 ? 131.697 96.571  91.509  1.00 59.85  ? 165 GLU C CG  1 
ATOM   6853  C CD  . GLU C 1 219 ? 132.157 95.171  91.161  1.00 78.11  ? 165 GLU C CD  1 
ATOM   6854  O OE1 . GLU C 1 219 ? 133.290 94.807  91.540  1.00 85.85  ? 165 GLU C OE1 1 
ATOM   6855  O OE2 . GLU C 1 219 ? 131.388 94.434  90.510  1.00 82.38  ? 165 GLU C OE2 1 
ATOM   6856  N N   . PHE C 1 220 ? 133.597 99.192  94.698  1.00 44.92  ? 166 PHE C N   1 
ATOM   6857  C CA  . PHE C 1 220 ? 134.630 99.791  95.530  1.00 42.07  ? 166 PHE C CA  1 
ATOM   6858  C C   . PHE C 1 220 ? 135.596 98.727  96.025  1.00 44.98  ? 166 PHE C C   1 
ATOM   6859  O O   . PHE C 1 220 ? 135.191 97.607  96.351  1.00 51.66  ? 166 PHE C O   1 
ATOM   6860  C CB  . PHE C 1 220 ? 134.026 100.517 96.735  1.00 40.11  ? 166 PHE C CB  1 
ATOM   6861  C CG  . PHE C 1 220 ? 133.426 101.849 96.409  1.00 37.05  ? 166 PHE C CG  1 
ATOM   6862  C CD1 . PHE C 1 220 ? 133.464 102.350 95.122  1.00 41.98  ? 166 PHE C CD1 1 
ATOM   6863  C CD2 . PHE C 1 220 ? 132.832 102.610 97.401  1.00 39.03  ? 166 PHE C CD2 1 
ATOM   6864  C CE1 . PHE C 1 220 ? 132.913 103.577 94.829  1.00 44.68  ? 166 PHE C CE1 1 
ATOM   6865  C CE2 . PHE C 1 220 ? 132.282 103.837 97.113  1.00 40.74  ? 166 PHE C CE2 1 
ATOM   6866  C CZ  . PHE C 1 220 ? 132.321 104.322 95.825  1.00 41.27  ? 166 PHE C CZ  1 
ATOM   6867  N N   . TYR C 1 221 ? 136.874 99.087  96.084  1.00 42.09  ? 167 TYR C N   1 
ATOM   6868  C CA  . TYR C 1 221 ? 137.877 98.247  96.717  1.00 41.65  ? 167 TYR C CA  1 
ATOM   6869  C C   . TYR C 1 221 ? 138.965 99.148  97.278  1.00 44.99  ? 167 TYR C C   1 
ATOM   6870  O O   . TYR C 1 221 ? 139.123 100.296 96.859  1.00 50.13  ? 167 TYR C O   1 
ATOM   6871  C CB  . TYR C 1 221 ? 138.458 97.216  95.740  1.00 40.92  ? 167 TYR C CB  1 
ATOM   6872  C CG  . TYR C 1 221 ? 139.356 97.790  94.667  1.00 45.75  ? 167 TYR C CG  1 
ATOM   6873  C CD1 . TYR C 1 221 ? 138.831 98.256  93.470  1.00 48.13  ? 167 TYR C CD1 1 
ATOM   6874  C CD2 . TYR C 1 221 ? 140.731 97.847  94.844  1.00 46.86  ? 167 TYR C CD2 1 
ATOM   6875  C CE1 . TYR C 1 221 ? 139.651 98.774  92.487  1.00 52.76  ? 167 TYR C CE1 1 
ATOM   6876  C CE2 . TYR C 1 221 ? 141.555 98.364  93.869  1.00 46.33  ? 167 TYR C CE2 1 
ATOM   6877  C CZ  . TYR C 1 221 ? 141.012 98.825  92.693  1.00 52.73  ? 167 TYR C CZ  1 
ATOM   6878  O OH  . TYR C 1 221 ? 141.835 99.339  91.720  1.00 61.60  ? 167 TYR C OH  1 
ATOM   6879  N N   . TRP C 1 222 ? 139.707 98.622  98.248  1.00 41.33  ? 168 TRP C N   1 
ATOM   6880  C CA  . TRP C 1 222 ? 140.819 99.351  98.847  1.00 42.64  ? 168 TRP C CA  1 
ATOM   6881  C C   . TRP C 1 222 ? 142.068 99.083  98.018  1.00 47.53  ? 168 TRP C C   1 
ATOM   6882  O O   . TRP C 1 222 ? 142.596 97.968  98.019  1.00 49.92  ? 168 TRP C O   1 
ATOM   6883  C CB  . TRP C 1 222 ? 141.027 98.938  100.301 1.00 45.47  ? 168 TRP C CB  1 
ATOM   6884  C CG  . TRP C 1 222 ? 139.941 99.386  101.225 1.00 41.71  ? 168 TRP C CG  1 
ATOM   6885  C CD1 . TRP C 1 222 ? 138.920 98.630  101.714 1.00 45.19  ? 168 TRP C CD1 1 
ATOM   6886  C CD2 . TRP C 1 222 ? 139.771 100.697 101.778 1.00 42.63  ? 168 TRP C CD2 1 
ATOM   6887  N NE1 . TRP C 1 222 ? 138.122 99.386  102.537 1.00 47.06  ? 168 TRP C NE1 1 
ATOM   6888  C CE2 . TRP C 1 222 ? 138.624 100.659 102.592 1.00 44.40  ? 168 TRP C CE2 1 
ATOM   6889  C CE3 . TRP C 1 222 ? 140.477 101.897 101.663 1.00 44.57  ? 168 TRP C CE3 1 
ATOM   6890  C CZ2 . TRP C 1 222 ? 138.166 101.775 103.287 1.00 41.77  ? 168 TRP C CZ2 1 
ATOM   6891  C CZ3 . TRP C 1 222 ? 140.022 103.002 102.353 1.00 42.67  ? 168 TRP C CZ3 1 
ATOM   6892  C CH2 . TRP C 1 222 ? 138.877 102.934 103.154 1.00 39.25  ? 168 TRP C CH2 1 
ATOM   6893  N N   . ARG C 1 223 ? 142.544 100.108 97.316  1.00 47.07  ? 169 ARG C N   1 
ATOM   6894  C CA  . ARG C 1 223 ? 143.709 99.964  96.451  1.00 46.99  ? 169 ARG C CA  1 
ATOM   6895  C C   . ARG C 1 223 ? 144.958 99.824  97.309  1.00 50.56  ? 169 ARG C C   1 
ATOM   6896  O O   . ARG C 1 223 ? 145.425 100.798 97.906  1.00 49.63  ? 169 ARG C O   1 
ATOM   6897  C CB  . ARG C 1 223 ? 143.815 101.161 95.513  1.00 48.43  ? 169 ARG C CB  1 
ATOM   6898  C CG  . ARG C 1 223 ? 145.008 101.121 94.586  1.00 51.11  ? 169 ARG C CG  1 
ATOM   6899  C CD  . ARG C 1 223 ? 145.009 102.331 93.676  1.00 56.20  ? 169 ARG C CD  1 
ATOM   6900  N NE  . ARG C 1 223 ? 146.177 102.362 92.807  1.00 69.77  ? 169 ARG C NE  1 
ATOM   6901  C CZ  . ARG C 1 223 ? 147.304 102.999 93.093  1.00 72.11  ? 169 ARG C CZ  1 
ATOM   6902  N NH1 . ARG C 1 223 ? 147.450 103.671 94.223  1.00 62.05  ? 169 ARG C NH1 1 
ATOM   6903  N NH2 . ARG C 1 223 ? 148.309 102.962 92.222  1.00 77.35  ? 169 ARG C NH2 1 
ATOM   6904  N N   . GLY C 1 224 ? 145.501 98.613  97.369  1.00 55.11  ? 170 GLY C N   1 
ATOM   6905  C CA  . GLY C 1 224 ? 146.640 98.312  98.220  1.00 56.25  ? 170 GLY C CA  1 
ATOM   6906  C C   . GLY C 1 224 ? 146.361 97.292  99.303  1.00 60.24  ? 170 GLY C C   1 
ATOM   6907  O O   . GLY C 1 224 ? 147.253 97.028  100.122 1.00 66.81  ? 170 GLY C O   1 
ATOM   6908  N N   . GLY C 1 225 ? 145.170 96.702  99.352  1.00 57.01  ? 171 GLY C N   1 
ATOM   6909  C CA  . GLY C 1 225 ? 144.852 95.715  100.364 1.00 62.03  ? 171 GLY C CA  1 
ATOM   6910  C C   . GLY C 1 225 ? 144.690 96.316  101.743 1.00 65.06  ? 171 GLY C C   1 
ATOM   6911  O O   . GLY C 1 225 ? 143.751 97.078  101.989 1.00 65.80  ? 171 GLY C O   1 
ATOM   6912  N N   . ASP C 1 226 ? 145.601 95.979  102.653 1.00 66.56  ? 172 ASP C N   1 
ATOM   6913  C CA  . ASP C 1 226 ? 145.592 96.538  103.997 1.00 66.27  ? 172 ASP C CA  1 
ATOM   6914  C C   . ASP C 1 226 ? 146.478 97.767  104.133 1.00 64.70  ? 172 ASP C C   1 
ATOM   6915  O O   . ASP C 1 226 ? 146.501 98.380  105.205 1.00 68.44  ? 172 ASP C O   1 
ATOM   6916  C CB  . ASP C 1 226 ? 146.029 95.479  105.015 1.00 71.92  ? 172 ASP C CB  1 
ATOM   6917  C CG  . ASP C 1 226 ? 145.077 94.301  105.078 1.00 87.84  ? 172 ASP C CG  1 
ATOM   6918  O OD1 . ASP C 1 226 ? 144.132 94.252  104.263 1.00 94.50  ? 172 ASP C OD1 1 
ATOM   6919  O OD2 . ASP C 1 226 ? 145.273 93.423  105.945 1.00 95.78  ? 172 ASP C OD2 1 
ATOM   6920  N N   . LYS C 1 227 ? 147.205 98.140  103.080 1.00 59.58  ? 173 LYS C N   1 
ATOM   6921  C CA  . LYS C 1 227 ? 148.035 99.335  103.081 1.00 60.45  ? 173 LYS C CA  1 
ATOM   6922  C C   . LYS C 1 227 ? 147.335 100.523 102.434 1.00 59.23  ? 173 LYS C C   1 
ATOM   6923  O O   . LYS C 1 227 ? 147.990 101.515 102.096 1.00 61.98  ? 173 LYS C O   1 
ATOM   6924  C CB  . LYS C 1 227 ? 149.363 99.058  102.377 1.00 63.58  ? 173 LYS C CB  1 
ATOM   6925  C CG  . LYS C 1 227 ? 150.180 97.946  103.010 1.00 67.45  ? 173 LYS C CG  1 
ATOM   6926  C CD  . LYS C 1 227 ? 151.545 97.834  102.352 1.00 74.47  ? 173 LYS C CD  1 
ATOM   6927  C CE  . LYS C 1 227 ? 152.374 96.724  102.975 1.00 80.96  ? 173 LYS C CE  1 
ATOM   6928  N NZ  . LYS C 1 227 ? 153.743 96.667  102.393 1.00 90.56  ? 173 LYS C NZ  1 
ATOM   6929  N N   . ALA C 1 228 ? 146.017 100.439 102.250 1.00 54.46  ? 174 ALA C N   1 
ATOM   6930  C CA  . ALA C 1 228 ? 145.285 101.525 101.608 1.00 46.79  ? 174 ALA C CA  1 
ATOM   6931  C C   . ALA C 1 228 ? 145.285 102.783 102.468 1.00 48.40  ? 174 ALA C C   1 
ATOM   6932  O O   . ALA C 1 228 ? 145.403 103.896 101.945 1.00 49.87  ? 174 ALA C O   1 
ATOM   6933  C CB  . ALA C 1 228 ? 143.857 101.082 101.301 1.00 44.72  ? 174 ALA C CB  1 
ATOM   6934  N N   . VAL C 1 229 ? 145.155 102.631 103.782 1.00 48.26  ? 175 VAL C N   1 
ATOM   6935  C CA  . VAL C 1 229 ? 145.132 103.759 104.705 1.00 44.71  ? 175 VAL C CA  1 
ATOM   6936  C C   . VAL C 1 229 ? 146.489 103.866 105.383 1.00 47.77  ? 175 VAL C C   1 
ATOM   6937  O O   . VAL C 1 229 ? 146.959 102.907 106.008 1.00 47.99  ? 175 VAL C O   1 
ATOM   6938  C CB  . VAL C 1 229 ? 144.003 103.614 105.739 1.00 40.70  ? 175 VAL C CB  1 
ATOM   6939  C CG1 . VAL C 1 229 ? 144.155 104.652 106.833 1.00 39.37  ? 175 VAL C CG1 1 
ATOM   6940  C CG2 . VAL C 1 229 ? 142.656 103.760 105.063 1.00 40.11  ? 175 VAL C CG2 1 
ATOM   6941  N N   . THR C 1 230 ? 147.118 105.032 105.261 1.00 49.40  ? 176 THR C N   1 
ATOM   6942  C CA  . THR C 1 230 ? 148.431 105.290 105.829 1.00 48.68  ? 176 THR C CA  1 
ATOM   6943  C C   . THR C 1 230 ? 148.368 106.532 106.707 1.00 53.71  ? 176 THR C C   1 
ATOM   6944  O O   . THR C 1 230 ? 147.426 107.325 106.630 1.00 57.66  ? 176 THR C O   1 
ATOM   6945  C CB  . THR C 1 230 ? 149.493 105.474 104.736 1.00 49.66  ? 176 THR C CB  1 
ATOM   6946  O OG1 . THR C 1 230 ? 149.105 106.545 103.867 1.00 51.29  ? 176 THR C OG1 1 
ATOM   6947  C CG2 . THR C 1 230 ? 149.645 104.203 103.921 1.00 49.24  ? 176 THR C CG2 1 
ATOM   6948  N N   . GLY C 1 231 ? 149.386 106.691 107.550 1.00 55.02  ? 177 GLY C N   1 
ATOM   6949  C CA  . GLY C 1 231 ? 149.460 107.819 108.453 1.00 59.81  ? 177 GLY C CA  1 
ATOM   6950  C C   . GLY C 1 231 ? 148.793 107.619 109.795 1.00 66.20  ? 177 GLY C C   1 
ATOM   6951  O O   . GLY C 1 231 ? 148.802 108.546 110.614 1.00 69.77  ? 177 GLY C O   1 
ATOM   6952  N N   . VAL C 1 232 ? 148.213 106.445 110.048 1.00 65.46  ? 178 VAL C N   1 
ATOM   6953  C CA  . VAL C 1 232 ? 147.575 106.194 111.336 1.00 68.59  ? 178 VAL C CA  1 
ATOM   6954  C C   . VAL C 1 232 ? 148.612 106.162 112.452 1.00 77.85  ? 178 VAL C C   1 
ATOM   6955  O O   . VAL C 1 232 ? 148.354 106.620 113.572 1.00 77.83  ? 178 VAL C O   1 
ATOM   6956  C CB  . VAL C 1 232 ? 146.762 104.889 111.280 1.00 63.18  ? 178 VAL C CB  1 
ATOM   6957  C CG1 . VAL C 1 232 ? 146.042 104.651 112.595 1.00 62.93  ? 178 VAL C CG1 1 
ATOM   6958  C CG2 . VAL C 1 232 ? 145.775 104.936 110.129 1.00 61.15  ? 178 VAL C CG2 1 
ATOM   6959  N N   . GLU C 1 233 ? 149.801 105.632 112.164 1.00 83.98  ? 179 GLU C N   1 
ATOM   6960  C CA  . GLU C 1 233 ? 150.848 105.518 113.172 1.00 82.15  ? 179 GLU C CA  1 
ATOM   6961  C C   . GLU C 1 233 ? 151.394 106.867 113.620 1.00 80.72  ? 179 GLU C C   1 
ATOM   6962  O O   . GLU C 1 233 ? 152.104 106.921 114.630 1.00 79.37  ? 179 GLU C O   1 
ATOM   6963  C CB  . GLU C 1 233 ? 151.995 104.649 112.644 1.00 84.47  ? 179 GLU C CB  1 
ATOM   6964  C CG  . GLU C 1 233 ? 152.808 105.277 111.515 1.00 89.26  ? 179 GLU C CG  1 
ATOM   6965  C CD  . GLU C 1 233 ? 152.100 105.229 110.173 1.00 88.04  ? 179 GLU C CD  1 
ATOM   6966  O OE1 . GLU C 1 233 ? 151.126 104.460 110.039 1.00 85.31  ? 179 GLU C OE1 1 
ATOM   6967  O OE2 . GLU C 1 233 ? 152.517 105.962 109.252 1.00 85.99  ? 179 GLU C OE2 1 
ATOM   6968  N N   . ARG C 1 234 ? 151.087 107.948 112.905 1.00 80.12  ? 180 ARG C N   1 
ATOM   6969  C CA  . ARG C 1 234 ? 151.582 109.276 113.244 1.00 81.28  ? 180 ARG C CA  1 
ATOM   6970  C C   . ARG C 1 234 ? 150.498 110.181 113.813 1.00 80.08  ? 180 ARG C C   1 
ATOM   6971  O O   . ARG C 1 234 ? 150.745 111.375 114.015 1.00 81.40  ? 180 ARG C O   1 
ATOM   6972  C CB  . ARG C 1 234 ? 152.218 109.929 112.015 1.00 81.57  ? 180 ARG C CB  1 
ATOM   6973  C CG  . ARG C 1 234 ? 153.377 109.144 111.425 1.00 86.12  ? 180 ARG C CG  1 
ATOM   6974  C CD  . ARG C 1 234 ? 154.004 109.866 110.238 1.00 89.91  ? 180 ARG C CD  1 
ATOM   6975  N NE  . ARG C 1 234 ? 153.079 110.019 109.120 1.00 90.63  ? 180 ARG C NE  1 
ATOM   6976  C CZ  . ARG C 1 234 ? 152.412 111.131 108.845 1.00 90.16  ? 180 ARG C CZ  1 
ATOM   6977  N NH1 . ARG C 1 234 ? 152.535 112.215 109.595 1.00 83.98  ? 180 ARG C NH1 1 
ATOM   6978  N NH2 . ARG C 1 234 ? 151.602 111.158 107.790 1.00 83.23  ? 180 ARG C NH2 1 
ATOM   6979  N N   . ILE C 1 235 ? 149.306 109.647 114.075 1.00 79.61  ? 181 ILE C N   1 
ATOM   6980  C CA  . ILE C 1 235 ? 148.223 110.455 114.621 1.00 77.53  ? 181 ILE C CA  1 
ATOM   6981  C C   . ILE C 1 235 ? 148.538 110.819 116.065 1.00 78.94  ? 181 ILE C C   1 
ATOM   6982  O O   . ILE C 1 235 ? 148.870 109.952 116.884 1.00 80.43  ? 181 ILE C O   1 
ATOM   6983  C CB  . ILE C 1 235 ? 146.887 109.707 114.508 1.00 73.45  ? 181 ILE C CB  1 
ATOM   6984  C CG1 . ILE C 1 235 ? 146.439 109.651 113.047 1.00 71.83  ? 181 ILE C CG1 1 
ATOM   6985  C CG2 . ILE C 1 235 ? 145.831 110.362 115.380 1.00 68.19  ? 181 ILE C CG2 1 
ATOM   6986  C CD1 . ILE C 1 235 ? 145.081 109.031 112.847 1.00 66.57  ? 181 ILE C CD1 1 
ATOM   6987  N N   . GLU C 1 236 ? 148.434 112.106 116.384 1.00 82.85  ? 182 GLU C N   1 
ATOM   6988  C CA  . GLU C 1 236 ? 148.787 112.632 117.701 1.00 80.47  ? 182 GLU C CA  1 
ATOM   6989  C C   . GLU C 1 236 ? 147.514 113.111 118.395 1.00 74.24  ? 182 GLU C C   1 
ATOM   6990  O O   . GLU C 1 236 ? 147.122 114.273 118.274 1.00 75.70  ? 182 GLU C O   1 
ATOM   6991  C CB  . GLU C 1 236 ? 149.812 113.754 117.574 1.00 89.05  ? 182 GLU C CB  1 
ATOM   6992  C CG  . GLU C 1 236 ? 151.109 113.324 116.911 1.00 99.54  ? 182 GLU C CG  1 
ATOM   6993  C CD  . GLU C 1 236 ? 151.977 114.499 116.509 1.00 110.39 ? 182 GLU C CD  1 
ATOM   6994  O OE1 . GLU C 1 236 ? 151.500 115.650 116.598 1.00 110.14 ? 182 GLU C OE1 1 
ATOM   6995  O OE2 . GLU C 1 236 ? 153.135 114.270 116.102 1.00 116.31 ? 182 GLU C OE2 1 
ATOM   6996  N N   . LEU C 1 237 ? 146.872 112.203 119.128 1.00 71.56  ? 183 LEU C N   1 
ATOM   6997  C CA  . LEU C 1 237 ? 145.728 112.555 119.955 1.00 71.23  ? 183 LEU C CA  1 
ATOM   6998  C C   . LEU C 1 237 ? 146.178 112.671 121.400 1.00 71.79  ? 183 LEU C C   1 
ATOM   6999  O O   . LEU C 1 237 ? 146.645 111.674 121.973 1.00 72.36  ? 183 LEU C O   1 
ATOM   7000  C CB  . LEU C 1 237 ? 144.624 111.513 119.826 1.00 70.67  ? 183 LEU C CB  1 
ATOM   7001  C CG  . LEU C 1 237 ? 143.601 111.731 118.711 1.00 65.69  ? 183 LEU C CG  1 
ATOM   7002  C CD1 . LEU C 1 237 ? 142.655 110.547 118.607 1.00 61.91  ? 183 LEU C CD1 1 
ATOM   7003  C CD2 . LEU C 1 237 ? 142.823 113.011 118.961 1.00 62.55  ? 183 LEU C CD2 1 
ATOM   7004  N N   . PRO C 1 238 ? 146.083 113.851 122.019 1.00 69.97  ? 184 PRO C N   1 
ATOM   7005  C CA  . PRO C 1 238 ? 146.551 113.987 123.407 1.00 70.49  ? 184 PRO C CA  1 
ATOM   7006  C C   . PRO C 1 238 ? 145.818 113.092 124.389 1.00 70.80  ? 184 PRO C C   1 
ATOM   7007  O O   . PRO C 1 238 ? 146.433 112.619 125.353 1.00 69.22  ? 184 PRO C O   1 
ATOM   7008  C CB  . PRO C 1 238 ? 146.311 115.472 123.715 1.00 72.44  ? 184 PRO C CB  1 
ATOM   7009  C CG  . PRO C 1 238 ? 146.224 116.136 122.374 1.00 71.71  ? 184 PRO C CG  1 
ATOM   7010  C CD  . PRO C 1 238 ? 145.597 115.125 121.468 1.00 70.65  ? 184 PRO C CD  1 
ATOM   7011  N N   . GLN C 1 239 ? 144.528 112.844 124.178 1.00 72.33  ? 185 GLN C N   1 
ATOM   7012  C CA  . GLN C 1 239 ? 143.719 112.096 125.131 1.00 69.86  ? 185 GLN C CA  1 
ATOM   7013  C C   . GLN C 1 239 ? 143.507 110.643 124.733 1.00 68.36  ? 185 GLN C C   1 
ATOM   7014  O O   . GLN C 1 239 ? 143.343 109.790 125.611 1.00 68.40  ? 185 GLN C O   1 
ATOM   7015  C CB  . GLN C 1 239 ? 142.357 112.777 125.306 1.00 72.86  ? 185 GLN C CB  1 
ATOM   7016  C CG  . GLN C 1 239 ? 141.540 112.269 126.481 1.00 77.65  ? 185 GLN C CG  1 
ATOM   7017  C CD  . GLN C 1 239 ? 140.254 113.049 126.671 1.00 85.57  ? 185 GLN C CD  1 
ATOM   7018  O OE1 . GLN C 1 239 ? 139.489 112.791 127.601 1.00 84.21  ? 185 GLN C OE1 1 
ATOM   7019  N NE2 . GLN C 1 239 ? 140.009 114.010 125.788 1.00 84.59  ? 185 GLN C NE2 1 
ATOM   7020  N N   . PHE C 1 240 ? 143.513 110.341 123.440 1.00 67.60  ? 186 PHE C N   1 
ATOM   7021  C CA  . PHE C 1 240 ? 143.273 108.999 122.937 1.00 62.59  ? 186 PHE C CA  1 
ATOM   7022  C C   . PHE C 1 240 ? 144.531 108.431 122.295 1.00 67.43  ? 186 PHE C C   1 
ATOM   7023  O O   . PHE C 1 240 ? 145.418 109.163 121.850 1.00 71.12  ? 186 PHE C O   1 
ATOM   7024  C CB  . PHE C 1 240 ? 142.134 108.992 121.914 1.00 64.70  ? 186 PHE C CB  1 
ATOM   7025  C CG  . PHE C 1 240 ? 140.789 109.302 122.494 1.00 66.93  ? 186 PHE C CG  1 
ATOM   7026  C CD1 . PHE C 1 240 ? 140.398 110.612 122.714 1.00 69.72  ? 186 PHE C CD1 1 
ATOM   7027  C CD2 . PHE C 1 240 ? 139.906 108.284 122.803 1.00 62.63  ? 186 PHE C CD2 1 
ATOM   7028  C CE1 . PHE C 1 240 ? 139.157 110.897 123.240 1.00 68.34  ? 186 PHE C CE1 1 
ATOM   7029  C CE2 . PHE C 1 240 ? 138.664 108.563 123.328 1.00 62.82  ? 186 PHE C CE2 1 
ATOM   7030  C CZ  . PHE C 1 240 ? 138.288 109.871 123.546 1.00 66.29  ? 186 PHE C CZ  1 
ATOM   7031  N N   . SER C 1 241 ? 144.593 107.103 122.251 1.00 67.49  ? 187 SER C N   1 
ATOM   7032  C CA  . SER C 1 241 ? 145.632 106.383 121.531 1.00 67.85  ? 187 SER C CA  1 
ATOM   7033  C C   . SER C 1 241 ? 144.974 105.349 120.631 1.00 68.88  ? 187 SER C C   1 
ATOM   7034  O O   . SER C 1 241 ? 144.050 104.648 121.055 1.00 70.64  ? 187 SER C O   1 
ATOM   7035  C CB  . SER C 1 241 ? 146.615 105.707 122.494 1.00 65.75  ? 187 SER C CB  1 
ATOM   7036  O OG  . SER C 1 241 ? 145.934 104.874 123.415 1.00 71.47  ? 187 SER C OG  1 
ATOM   7037  N N   . ILE C 1 242 ? 145.455 105.248 119.396 1.00 63.16  ? 188 ILE C N   1 
ATOM   7038  C CA  . ILE C 1 242 ? 144.840 104.385 118.393 1.00 60.46  ? 188 ILE C CA  1 
ATOM   7039  C C   . ILE C 1 242 ? 145.392 102.976 118.567 1.00 66.45  ? 188 ILE C C   1 
ATOM   7040  O O   . ILE C 1 242 ? 146.543 102.700 118.223 1.00 70.78  ? 188 ILE C O   1 
ATOM   7041  C CB  . ILE C 1 242 ? 145.084 104.907 116.973 1.00 60.38  ? 188 ILE C CB  1 
ATOM   7042  C CG1 . ILE C 1 242 ? 144.475 106.298 116.814 1.00 65.92  ? 188 ILE C CG1 1 
ATOM   7043  C CG2 . ILE C 1 242 ? 144.509 103.941 115.948 1.00 65.34  ? 188 ILE C CG2 1 
ATOM   7044  C CD1 . ILE C 1 242 ? 144.194 106.685 115.386 1.00 70.65  ? 188 ILE C CD1 1 
ATOM   7045  N N   . VAL C 1 243 ? 144.563 102.081 119.108 1.00 67.71  ? 189 VAL C N   1 
ATOM   7046  C CA  . VAL C 1 243 ? 144.980 100.698 119.306 1.00 67.87  ? 189 VAL C CA  1 
ATOM   7047  C C   . VAL C 1 243 ? 145.083 99.967  117.973 1.00 72.54  ? 189 VAL C C   1 
ATOM   7048  O O   . VAL C 1 243 ? 146.050 99.237  117.724 1.00 76.70  ? 189 VAL C O   1 
ATOM   7049  C CB  . VAL C 1 243 ? 144.013 99.985  120.268 1.00 64.14  ? 189 VAL C CB  1 
ATOM   7050  C CG1 . VAL C 1 243 ? 144.326 98.500  120.335 1.00 65.31  ? 189 VAL C CG1 1 
ATOM   7051  C CG2 . VAL C 1 243 ? 144.089 100.609 121.648 1.00 64.97  ? 189 VAL C CG2 1 
ATOM   7052  N N   . GLU C 1 244 ? 144.102 100.153 117.094 1.00 69.98  ? 190 GLU C N   1 
ATOM   7053  C CA  . GLU C 1 244 ? 144.039 99.376  115.865 1.00 67.26  ? 190 GLU C CA  1 
ATOM   7054  C C   . GLU C 1 244 ? 143.184 100.115 114.848 1.00 64.85  ? 190 GLU C C   1 
ATOM   7055  O O   . GLU C 1 244 ? 142.320 100.921 115.204 1.00 68.65  ? 190 GLU C O   1 
ATOM   7056  C CB  . GLU C 1 244 ? 143.471 97.976  116.131 1.00 71.35  ? 190 GLU C CB  1 
ATOM   7057  C CG  . GLU C 1 244 ? 143.596 97.001  114.972 1.00 78.31  ? 190 GLU C CG  1 
ATOM   7058  C CD  . GLU C 1 244 ? 142.677 95.805  115.119 1.00 87.36  ? 190 GLU C CD  1 
ATOM   7059  O OE1 . GLU C 1 244 ? 141.627 95.938  115.782 1.00 86.29  ? 190 GLU C OE1 1 
ATOM   7060  O OE2 . GLU C 1 244 ? 143.004 94.731  114.573 1.00 92.54  ? 190 GLU C OE2 1 
ATOM   7061  N N   . HIS C 1 245 ? 143.440 99.829  113.573 1.00 64.42  ? 191 HIS C N   1 
ATOM   7062  C CA  . HIS C 1 245 ? 142.607 100.304 112.479 1.00 62.04  ? 191 HIS C CA  1 
ATOM   7063  C C   . HIS C 1 245 ? 142.328 99.152  111.524 1.00 64.07  ? 191 HIS C C   1 
ATOM   7064  O O   . HIS C 1 245 ? 143.163 98.264  111.332 1.00 70.84  ? 191 HIS C O   1 
ATOM   7065  C CB  . HIS C 1 245 ? 143.258 101.474 111.726 1.00 54.03  ? 191 HIS C CB  1 
ATOM   7066  C CG  . HIS C 1 245 ? 144.382 101.065 110.827 1.00 58.28  ? 191 HIS C CG  1 
ATOM   7067  N ND1 . HIS C 1 245 ? 145.659 100.831 111.290 1.00 62.13  ? 191 HIS C ND1 1 
ATOM   7068  C CD2 . HIS C 1 245 ? 144.422 100.854 109.491 1.00 58.16  ? 191 HIS C CD2 1 
ATOM   7069  C CE1 . HIS C 1 245 ? 146.436 100.491 110.278 1.00 62.50  ? 191 HIS C CE1 1 
ATOM   7070  N NE2 . HIS C 1 245 ? 145.710 100.497 109.175 1.00 61.26  ? 191 HIS C NE2 1 
ATOM   7071  N N   . ARG C 1 246 ? 141.139 99.181  110.929 1.00 60.11  ? 192 ARG C N   1 
ATOM   7072  C CA  . ARG C 1 246 ? 140.656 98.110  110.069 1.00 55.26  ? 192 ARG C CA  1 
ATOM   7073  C C   . ARG C 1 246 ? 140.051 98.677  108.795 1.00 56.78  ? 192 ARG C C   1 
ATOM   7074  O O   . ARG C 1 246 ? 139.531 99.796  108.777 1.00 61.19  ? 192 ARG C O   1 
ATOM   7075  C CB  . ARG C 1 246 ? 139.598 97.253  110.768 1.00 54.84  ? 192 ARG C CB  1 
ATOM   7076  C CG  . ARG C 1 246 ? 140.131 96.283  111.794 1.00 70.09  ? 192 ARG C CG  1 
ATOM   7077  C CD  . ARG C 1 246 ? 138.982 95.517  112.419 1.00 78.00  ? 192 ARG C CD  1 
ATOM   7078  N NE  . ARG C 1 246 ? 139.427 94.583  113.444 1.00 85.30  ? 192 ARG C NE  1 
ATOM   7079  C CZ  . ARG C 1 246 ? 138.615 93.947  114.276 1.00 87.11  ? 192 ARG C CZ  1 
ATOM   7080  N NH1 . ARG C 1 246 ? 137.305 94.132  114.238 1.00 89.33  ? 192 ARG C NH1 1 
ATOM   7081  N NH2 . ARG C 1 246 ? 139.128 93.108  115.170 1.00 87.42  ? 192 ARG C NH2 1 
ATOM   7082  N N   . LEU C 1 247 ? 140.100 97.872  107.735 1.00 53.72  ? 193 LEU C N   1 
ATOM   7083  C CA  . LEU C 1 247 ? 139.477 98.183  106.456 1.00 47.78  ? 193 LEU C CA  1 
ATOM   7084  C C   . LEU C 1 247 ? 138.439 97.118  106.139 1.00 50.15  ? 193 LEU C C   1 
ATOM   7085  O O   . LEU C 1 247 ? 138.749 95.923  106.158 1.00 52.24  ? 193 LEU C O   1 
ATOM   7086  C CB  . LEU C 1 247 ? 140.515 98.248  105.336 1.00 46.12  ? 193 LEU C CB  1 
ATOM   7087  C CG  . LEU C 1 247 ? 141.708 99.171  105.563 1.00 44.99  ? 193 LEU C CG  1 
ATOM   7088  C CD1 . LEU C 1 247 ? 142.597 99.196  104.336 1.00 49.44  ? 193 LEU C CD1 1 
ATOM   7089  C CD2 . LEU C 1 247 ? 141.226 100.562 105.902 1.00 46.71  ? 193 LEU C CD2 1 
ATOM   7090  N N   . VAL C 1 248 ? 137.216 97.548  105.844 1.00 49.84  ? 194 VAL C N   1 
ATOM   7091  C CA  . VAL C 1 248 ? 136.112 96.646  105.543 1.00 46.29  ? 194 VAL C CA  1 
ATOM   7092  C C   . VAL C 1 248 ? 135.526 97.028  104.192 1.00 51.84  ? 194 VAL C C   1 
ATOM   7093  O O   . VAL C 1 248 ? 135.372 98.214  103.891 1.00 57.83  ? 194 VAL C O   1 
ATOM   7094  C CB  . VAL C 1 248 ? 135.030 96.691  106.642 1.00 51.80  ? 194 VAL C CB  1 
ATOM   7095  C CG1 . VAL C 1 248 ? 133.948 95.661  106.373 1.00 62.98  ? 194 VAL C CG1 1 
ATOM   7096  C CG2 . VAL C 1 248 ? 135.652 96.468  108.013 1.00 63.23  ? 194 VAL C CG2 1 
ATOM   7097  N N   . SER C 1 249 ? 135.210 96.027  103.374 1.00 53.01  ? 195 SER C N   1 
ATOM   7098  C CA  . SER C 1 249 ? 134.579 96.246  102.078 1.00 50.85  ? 195 SER C CA  1 
ATOM   7099  C C   . SER C 1 249 ? 133.394 95.305  101.946 1.00 55.28  ? 195 SER C C   1 
ATOM   7100  O O   . SER C 1 249 ? 133.520 94.109  102.222 1.00 66.86  ? 195 SER C O   1 
ATOM   7101  C CB  . SER C 1 249 ? 135.567 96.017  100.932 1.00 51.59  ? 195 SER C CB  1 
ATOM   7102  O OG  . SER C 1 249 ? 134.945 96.229  99.678  1.00 58.52  ? 195 SER C OG  1 
ATOM   7103  N N   . ARG C 1 250 ? 132.254 95.833  101.517 1.00 52.09  ? 196 ARG C N   1 
ATOM   7104  C CA  . ARG C 1 250 ? 131.033 95.031  101.456 1.00 58.88  ? 196 ARG C CA  1 
ATOM   7105  C C   . ARG C 1 250 ? 130.011 95.757  100.588 1.00 61.69  ? 196 ARG C C   1 
ATOM   7106  O O   . ARG C 1 250 ? 130.318 96.770  99.949  1.00 65.77  ? 196 ARG C O   1 
ATOM   7107  C CB  . ARG C 1 250 ? 130.491 94.757  102.858 1.00 60.92  ? 196 ARG C CB  1 
ATOM   7108  C CG  . ARG C 1 250 ? 130.129 96.011  103.628 1.00 54.28  ? 196 ARG C CG  1 
ATOM   7109  C CD  . ARG C 1 250 ? 129.964 95.718  105.104 1.00 60.39  ? 196 ARG C CD  1 
ATOM   7110  N NE  . ARG C 1 250 ? 129.328 96.824  105.809 1.00 59.43  ? 196 ARG C NE  1 
ATOM   7111  C CZ  . ARG C 1 250 ? 128.028 96.901  106.057 1.00 59.71  ? 196 ARG C CZ  1 
ATOM   7112  N NH1 . ARG C 1 250 ? 127.195 95.948  105.673 1.00 65.00  ? 196 ARG C NH1 1 
ATOM   7113  N NH2 . ARG C 1 250 ? 127.554 97.959  106.708 1.00 57.55  ? 196 ARG C NH2 1 
ATOM   7114  N N   . ASN C 1 251 ? 128.791 95.225  100.560 1.00 60.07  ? 197 ASN C N   1 
ATOM   7115  C CA  . ASN C 1 251 ? 127.664 95.832  99.870  1.00 58.31  ? 197 ASN C CA  1 
ATOM   7116  C C   . ASN C 1 251 ? 126.511 95.985  100.850 1.00 63.98  ? 197 ASN C C   1 
ATOM   7117  O O   . ASN C 1 251 ? 126.309 95.142  101.728 1.00 68.07  ? 197 ASN C O   1 
ATOM   7118  C CB  . ASN C 1 251 ? 127.214 94.992  98.667  1.00 62.21  ? 197 ASN C CB  1 
ATOM   7119  C CG  . ASN C 1 251 ? 128.255 94.935  97.567  1.00 67.49  ? 197 ASN C CG  1 
ATOM   7120  O OD1 . ASN C 1 251 ? 129.348 95.480  97.701  1.00 71.08  ? 197 ASN C OD1 1 
ATOM   7121  N ND2 . ASN C 1 251 ? 127.920 94.264  96.472  1.00 65.36  ? 197 ASN C ND2 1 
ATOM   7122  N N   . VAL C 1 252 ? 125.753 97.067  100.695 1.00 63.10  ? 198 VAL C N   1 
ATOM   7123  C CA  . VAL C 1 252 ? 124.632 97.369  101.578 1.00 66.84  ? 198 VAL C CA  1 
ATOM   7124  C C   . VAL C 1 252 ? 123.385 97.568  100.731 1.00 69.55  ? 198 VAL C C   1 
ATOM   7125  O O   . VAL C 1 252 ? 123.419 98.264  99.712  1.00 71.24  ? 198 VAL C O   1 
ATOM   7126  C CB  . VAL C 1 252 ? 124.912 98.608  102.452 1.00 64.98  ? 198 VAL C CB  1 
ATOM   7127  C CG1 . VAL C 1 252 ? 125.864 98.250  103.577 1.00 60.30  ? 198 VAL C CG1 1 
ATOM   7128  C CG2 . VAL C 1 252 ? 125.495 99.728  101.611 1.00 63.24  ? 198 VAL C CG2 1 
ATOM   7129  N N   . VAL C 1 253 ? 122.284 96.955  101.152 1.00 69.95  ? 199 VAL C N   1 
ATOM   7130  C CA  . VAL C 1 253 ? 121.054 96.922  100.369 1.00 74.98  ? 199 VAL C CA  1 
ATOM   7131  C C   . VAL C 1 253 ? 120.064 97.913  100.963 1.00 80.82  ? 199 VAL C C   1 
ATOM   7132  O O   . VAL C 1 253 ? 119.676 97.792  102.131 1.00 82.17  ? 199 VAL C O   1 
ATOM   7133  C CB  . VAL C 1 253 ? 120.455 95.508  100.329 1.00 72.85  ? 199 VAL C CB  1 
ATOM   7134  C CG1 . VAL C 1 253 ? 119.295 95.451  99.347  1.00 70.83  ? 199 VAL C CG1 1 
ATOM   7135  C CG2 . VAL C 1 253 ? 121.523 94.491  99.966  1.00 72.38  ? 199 VAL C CG2 1 
ATOM   7136  N N   . PHE C 1 254 ? 119.656 98.891  100.162 1.00 80.85  ? 200 PHE C N   1 
ATOM   7137  C CA  . PHE C 1 254 ? 118.572 99.803  100.483 1.00 82.75  ? 200 PHE C CA  1 
ATOM   7138  C C   . PHE C 1 254 ? 117.430 99.579  99.498  1.00 85.25  ? 200 PHE C C   1 
ATOM   7139  O O   . PHE C 1 254 ? 117.535 98.786  98.556  1.00 88.00  ? 200 PHE C O   1 
ATOM   7140  C CB  . PHE C 1 254 ? 119.053 101.255 100.451 1.00 81.60  ? 200 PHE C CB  1 
ATOM   7141  C CG  . PHE C 1 254 ? 120.251 101.513 101.312 1.00 85.95  ? 200 PHE C CG  1 
ATOM   7142  C CD1 . PHE C 1 254 ? 120.121 101.636 102.684 1.00 87.69  ? 200 PHE C CD1 1 
ATOM   7143  C CD2 . PHE C 1 254 ? 121.510 101.633 100.750 1.00 79.18  ? 200 PHE C CD2 1 
ATOM   7144  C CE1 . PHE C 1 254 ? 121.223 101.872 103.479 1.00 83.67  ? 200 PHE C CE1 1 
ATOM   7145  C CE2 . PHE C 1 254 ? 122.615 101.869 101.539 1.00 76.23  ? 200 PHE C CE2 1 
ATOM   7146  C CZ  . PHE C 1 254 ? 122.472 101.989 102.906 1.00 78.49  ? 200 PHE C CZ  1 
ATOM   7147  N N   . ALA C 1 255 ? 116.332 100.307 99.713  1.00 86.11  ? 201 ALA C N   1 
ATOM   7148  C CA  . ALA C 1 255 ? 115.147 100.131 98.884  1.00 90.36  ? 201 ALA C CA  1 
ATOM   7149  C C   . ALA C 1 255 ? 115.411 100.427 97.414  1.00 90.18  ? 201 ALA C C   1 
ATOM   7150  O O   . ALA C 1 255 ? 114.658 99.954  96.555  1.00 89.17  ? 201 ALA C O   1 
ATOM   7151  C CB  . ALA C 1 255 ? 114.012 101.018 99.395  1.00 93.27  ? 201 ALA C CB  1 
ATOM   7152  N N   . THR C 1 256 ? 116.454 101.191 97.101  1.00 88.95  ? 202 THR C N   1 
ATOM   7153  C CA  . THR C 1 256 ? 116.779 101.517 95.720  1.00 85.60  ? 202 THR C CA  1 
ATOM   7154  C C   . THR C 1 256 ? 117.815 100.581 95.106  1.00 82.86  ? 202 THR C C   1 
ATOM   7155  O O   . THR C 1 256 ? 118.155 100.751 93.932  1.00 78.54  ? 202 THR C O   1 
ATOM   7156  C CB  . THR C 1 256 ? 117.271 102.965 95.617  1.00 81.98  ? 202 THR C CB  1 
ATOM   7157  O OG1 . THR C 1 256 ? 118.472 103.121 96.383  1.00 85.09  ? 202 THR C OG1 1 
ATOM   7158  C CG2 . THR C 1 256 ? 116.216 103.924 96.144  1.00 81.18  ? 202 THR C CG2 1 
ATOM   7159  N N   . GLY C 1 257 ? 118.323 99.602  95.858  1.00 81.50  ? 203 GLY C N   1 
ATOM   7160  C CA  . GLY C 1 257 ? 119.258 98.637  95.323  1.00 75.95  ? 203 GLY C CA  1 
ATOM   7161  C C   . GLY C 1 257 ? 120.431 98.430  96.252  1.00 74.92  ? 203 GLY C C   1 
ATOM   7162  O O   . GLY C 1 257 ? 120.438 98.881  97.400  1.00 80.64  ? 203 GLY C O   1 
ATOM   7163  N N   . ALA C 1 258 ? 121.449 97.738  95.750  1.00 70.27  ? 204 ALA C N   1 
ATOM   7164  C CA  . ALA C 1 258 ? 122.646 97.431  96.522  1.00 66.53  ? 204 ALA C CA  1 
ATOM   7165  C C   . ALA C 1 258 ? 123.774 98.372  96.119  1.00 61.24  ? 204 ALA C C   1 
ATOM   7166  O O   . ALA C 1 258 ? 124.048 98.545  94.928  1.00 64.62  ? 204 ALA C O   1 
ATOM   7167  C CB  . ALA C 1 258 ? 123.070 95.976  96.320  1.00 63.65  ? 204 ALA C CB  1 
ATOM   7168  N N   . TYR C 1 259 ? 124.426 98.970  97.115  1.00 58.61  ? 205 TYR C N   1 
ATOM   7169  C CA  . TYR C 1 259 ? 125.474 99.954  96.922  1.00 53.91  ? 205 TYR C CA  1 
ATOM   7170  C C   . TYR C 1 259 ? 126.777 99.483  97.556  1.00 58.40  ? 205 TYR C C   1 
ATOM   7171  O O   . TYR C 1 259 ? 126.757 98.851  98.618  1.00 64.48  ? 205 TYR C O   1 
ATOM   7172  C CB  . TYR C 1 259 ? 125.074 101.305 97.537  1.00 54.68  ? 205 TYR C CB  1 
ATOM   7173  C CG  . TYR C 1 259 ? 123.843 101.930 96.921  1.00 58.53  ? 205 TYR C CG  1 
ATOM   7174  C CD1 . TYR C 1 259 ? 122.571 101.518 97.290  1.00 64.19  ? 205 TYR C CD1 1 
ATOM   7175  C CD2 . TYR C 1 259 ? 123.955 102.942 95.979  1.00 57.06  ? 205 TYR C CD2 1 
ATOM   7176  C CE1 . TYR C 1 259 ? 121.446 102.089 96.730  1.00 65.98  ? 205 TYR C CE1 1 
ATOM   7177  C CE2 . TYR C 1 259 ? 122.835 103.519 95.416  1.00 56.62  ? 205 TYR C CE2 1 
ATOM   7178  C CZ  . TYR C 1 259 ? 121.583 103.089 95.795  1.00 62.24  ? 205 TYR C CZ  1 
ATOM   7179  O OH  . TYR C 1 259 ? 120.465 103.661 95.236  1.00 68.30  ? 205 TYR C OH  1 
ATOM   7180  N N   . PRO C 1 260 ? 127.919 99.777  96.938  1.00 52.64  ? 206 PRO C N   1 
ATOM   7181  C CA  . PRO C 1 260 ? 129.202 99.417  97.549  1.00 53.23  ? 206 PRO C CA  1 
ATOM   7182  C C   . PRO C 1 260 ? 129.450 100.217 98.816  1.00 51.89  ? 206 PRO C C   1 
ATOM   7183  O O   . PRO C 1 260 ? 128.946 101.329 98.983  1.00 58.04  ? 206 PRO C O   1 
ATOM   7184  C CB  . PRO C 1 260 ? 130.223 99.768  96.462  1.00 46.58  ? 206 PRO C CB  1 
ATOM   7185  C CG  . PRO C 1 260 ? 129.554 100.831 95.663  1.00 43.57  ? 206 PRO C CG  1 
ATOM   7186  C CD  . PRO C 1 260 ? 128.096 100.482 95.658  1.00 48.56  ? 206 PRO C CD  1 
ATOM   7187  N N   . ARG C 1 261 ? 130.244 99.640  99.716  1.00 44.71  ? 207 ARG C N   1 
ATOM   7188  C CA  . ARG C 1 261 ? 130.501 100.264 101.006 1.00 43.66  ? 207 ARG C CA  1 
ATOM   7189  C C   . ARG C 1 261 ? 131.915 99.935  101.457 1.00 48.59  ? 207 ARG C C   1 
ATOM   7190  O O   . ARG C 1 261 ? 132.328 98.771  101.419 1.00 57.52  ? 207 ARG C O   1 
ATOM   7191  C CB  . ARG C 1 261 ? 129.494 99.788  102.055 1.00 49.04  ? 207 ARG C CB  1 
ATOM   7192  C CG  . ARG C 1 261 ? 129.722 100.369 103.437 1.00 50.51  ? 207 ARG C CG  1 
ATOM   7193  C CD  . ARG C 1 261 ? 129.174 101.774 103.531 1.00 50.18  ? 207 ARG C CD  1 
ATOM   7194  N NE  . ARG C 1 261 ? 127.717 101.779 103.504 1.00 54.28  ? 207 ARG C NE  1 
ATOM   7195  C CZ  . ARG C 1 261 ? 126.953 101.691 104.582 1.00 55.09  ? 207 ARG C CZ  1 
ATOM   7196  N NH1 . ARG C 1 261 ? 127.477 101.599 105.793 1.00 52.44  ? 207 ARG C NH1 1 
ATOM   7197  N NH2 . ARG C 1 261 ? 125.630 101.696 104.443 1.00 56.45  ? 207 ARG C NH2 1 
ATOM   7198  N N   . LEU C 1 262 ? 132.641 100.962 101.888 1.00 43.98  ? 208 LEU C N   1 
ATOM   7199  C CA  . LEU C 1 262 ? 133.951 100.815 102.499 1.00 40.49  ? 208 LEU C CA  1 
ATOM   7200  C C   . LEU C 1 262 ? 133.907 101.407 103.899 1.00 45.70  ? 208 LEU C C   1 
ATOM   7201  O O   . LEU C 1 262 ? 133.164 102.350 104.165 1.00 54.09  ? 208 LEU C O   1 
ATOM   7202  C CB  . LEU C 1 262 ? 135.040 101.507 101.673 1.00 39.52  ? 208 LEU C CB  1 
ATOM   7203  C CG  . LEU C 1 262 ? 135.190 101.062 100.219 1.00 40.98  ? 208 LEU C CG  1 
ATOM   7204  C CD1 . LEU C 1 262 ? 136.385 101.736 99.570  1.00 43.15  ? 208 LEU C CD1 1 
ATOM   7205  C CD2 . LEU C 1 262 ? 135.321 99.556  100.140 1.00 44.04  ? 208 LEU C CD2 1 
ATOM   7206  N N   . SER C 1 263 ? 134.697 100.837 104.801 1.00 44.13  ? 209 SER C N   1 
ATOM   7207  C CA  . SER C 1 263 ? 134.707 101.290 106.183 1.00 43.66  ? 209 SER C CA  1 
ATOM   7208  C C   . SER C 1 263 ? 136.137 101.339 106.688 1.00 46.81  ? 209 SER C C   1 
ATOM   7209  O O   . SER C 1 263 ? 136.873 100.355 106.575 1.00 53.02  ? 209 SER C O   1 
ATOM   7210  C CB  . SER C 1 263 ? 133.863 100.373 107.073 1.00 48.24  ? 209 SER C CB  1 
ATOM   7211  O OG  . SER C 1 263 ? 132.520 100.321 106.623 1.00 50.62  ? 209 SER C OG  1 
ATOM   7212  N N   . LEU C 1 264 ? 136.517 102.482 107.246 1.00 47.00  ? 210 LEU C N   1 
ATOM   7213  C CA  . LEU C 1 264 ? 137.806 102.661 107.903 1.00 45.77  ? 210 LEU C CA  1 
ATOM   7214  C C   . LEU C 1 264 ? 137.534 102.809 109.393 1.00 47.65  ? 210 LEU C C   1 
ATOM   7215  O O   . LEU C 1 264 ? 136.944 103.804 109.822 1.00 54.91  ? 210 LEU C O   1 
ATOM   7216  C CB  . LEU C 1 264 ? 138.540 103.877 107.342 1.00 45.58  ? 210 LEU C CB  1 
ATOM   7217  C CG  . LEU C 1 264 ? 139.755 104.387 108.116 1.00 49.66  ? 210 LEU C CG  1 
ATOM   7218  C CD1 . LEU C 1 264 ? 140.787 103.290 108.289 1.00 49.72  ? 210 LEU C CD1 1 
ATOM   7219  C CD2 . LEU C 1 264 ? 140.361 105.588 107.408 1.00 48.48  ? 210 LEU C CD2 1 
ATOM   7220  N N   . SER C 1 265 ? 137.950 101.823 110.179 1.00 46.13  ? 211 SER C N   1 
ATOM   7221  C CA  . SER C 1 265 ? 137.618 101.765 111.595 1.00 49.38  ? 211 SER C CA  1 
ATOM   7222  C C   . SER C 1 265 ? 138.854 102.014 112.444 1.00 55.29  ? 211 SER C C   1 
ATOM   7223  O O   . SER C 1 265 ? 139.931 101.495 112.145 1.00 65.92  ? 211 SER C O   1 
ATOM   7224  C CB  . SER C 1 265 ? 137.013 100.407 111.955 1.00 56.00  ? 211 SER C CB  1 
ATOM   7225  O OG  . SER C 1 265 ? 135.983 100.053 111.052 1.00 61.19  ? 211 SER C OG  1 
ATOM   7226  N N   . PHE C 1 266 ? 138.693 102.803 113.505 1.00 53.30  ? 212 PHE C N   1 
ATOM   7227  C CA  . PHE C 1 266 ? 139.722 103.003 114.513 1.00 50.92  ? 212 PHE C CA  1 
ATOM   7228  C C   . PHE C 1 266 ? 139.182 102.578 115.867 1.00 54.84  ? 212 PHE C C   1 
ATOM   7229  O O   . PHE C 1 266 ? 138.006 102.803 116.175 1.00 63.63  ? 212 PHE C O   1 
ATOM   7230  C CB  . PHE C 1 266 ? 140.166 104.465 114.609 1.00 51.00  ? 212 PHE C CB  1 
ATOM   7231  C CG  . PHE C 1 266 ? 140.376 105.128 113.288 1.00 59.12  ? 212 PHE C CG  1 
ATOM   7232  C CD1 . PHE C 1 266 ? 141.553 104.947 112.588 1.00 61.18  ? 212 PHE C CD1 1 
ATOM   7233  C CD2 . PHE C 1 266 ? 139.404 105.956 112.758 1.00 63.66  ? 212 PHE C CD2 1 
ATOM   7234  C CE1 . PHE C 1 266 ? 141.749 105.565 111.376 1.00 63.74  ? 212 PHE C CE1 1 
ATOM   7235  C CE2 . PHE C 1 266 ? 139.594 106.577 111.548 1.00 62.79  ? 212 PHE C CE2 1 
ATOM   7236  C CZ  . PHE C 1 266 ? 140.768 106.382 110.856 1.00 63.29  ? 212 PHE C CZ  1 
ATOM   7237  N N   . ARG C 1 267 ? 140.045 101.976 116.678 1.00 54.17  ? 213 ARG C N   1 
ATOM   7238  C CA  . ARG C 1 267 ? 139.731 101.672 118.068 1.00 57.45  ? 213 ARG C CA  1 
ATOM   7239  C C   . ARG C 1 267 ? 140.583 102.579 118.945 1.00 57.16  ? 213 ARG C C   1 
ATOM   7240  O O   . ARG C 1 267 ? 141.802 102.402 119.035 1.00 58.91  ? 213 ARG C O   1 
ATOM   7241  C CB  . ARG C 1 267 ? 139.970 100.200 118.388 1.00 58.87  ? 213 ARG C CB  1 
ATOM   7242  C CG  . ARG C 1 267 ? 139.580 99.831  119.807 1.00 63.97  ? 213 ARG C CG  1 
ATOM   7243  C CD  . ARG C 1 267 ? 139.253 98.355  119.947 1.00 68.59  ? 213 ARG C CD  1 
ATOM   7244  N NE  . ARG C 1 267 ? 140.399 97.500  119.667 1.00 76.91  ? 213 ARG C NE  1 
ATOM   7245  C CZ  . ARG C 1 267 ? 140.559 96.805  118.549 1.00 82.45  ? 213 ARG C CZ  1 
ATOM   7246  N NH1 . ARG C 1 267 ? 139.661 96.840  117.579 1.00 83.39  ? 213 ARG C NH1 1 
ATOM   7247  N NH2 . ARG C 1 267 ? 141.646 96.052  118.404 1.00 82.26  ? 213 ARG C NH2 1 
ATOM   7248  N N   . LEU C 1 268 ? 139.939 103.548 119.586 1.00 56.33  ? 214 LEU C N   1 
ATOM   7249  C CA  . LEU C 1 268 ? 140.612 104.543 120.407 1.00 57.27  ? 214 LEU C CA  1 
ATOM   7250  C C   . LEU C 1 268 ? 140.513 104.150 121.873 1.00 62.03  ? 214 LEU C C   1 
ATOM   7251  O O   . LEU C 1 268 ? 139.418 103.871 122.372 1.00 67.95  ? 214 LEU C O   1 
ATOM   7252  C CB  . LEU C 1 268 ? 139.997 105.926 120.201 1.00 56.39  ? 214 LEU C CB  1 
ATOM   7253  C CG  . LEU C 1 268 ? 139.823 106.440 118.774 1.00 57.71  ? 214 LEU C CG  1 
ATOM   7254  C CD1 . LEU C 1 268 ? 139.034 107.737 118.781 1.00 60.40  ? 214 LEU C CD1 1 
ATOM   7255  C CD2 . LEU C 1 268 ? 141.171 106.642 118.118 1.00 55.12  ? 214 LEU C CD2 1 
ATOM   7256  N N   . LYS C 1 269 ? 141.649 104.147 122.561 1.00 63.53  ? 215 LYS C N   1 
ATOM   7257  C CA  . LYS C 1 269 ? 141.705 103.851 123.984 1.00 63.14  ? 215 LYS C CA  1 
ATOM   7258  C C   . LYS C 1 269 ? 142.065 105.121 124.738 1.00 64.78  ? 215 LYS C C   1 
ATOM   7259  O O   . LYS C 1 269 ? 143.092 105.746 124.454 1.00 70.79  ? 215 LYS C O   1 
ATOM   7260  C CB  . LYS C 1 269 ? 142.722 102.748 124.278 1.00 62.57  ? 215 LYS C CB  1 
ATOM   7261  C CG  . LYS C 1 269 ? 142.725 102.287 125.721 1.00 65.37  ? 215 LYS C CG  1 
ATOM   7262  C CD  . LYS C 1 269 ? 143.724 101.168 125.931 1.00 76.28  ? 215 LYS C CD  1 
ATOM   7263  C CE  . LYS C 1 269 ? 143.738 100.711 127.378 1.00 86.94  ? 215 LYS C CE  1 
ATOM   7264  N NZ  . LYS C 1 269 ? 144.747 99.640  127.603 1.00 92.26  ? 215 LYS C NZ  1 
ATOM   7265  N N   . ARG C 1 270 ? 141.222 105.497 125.693 1.00 60.23  ? 216 ARG C N   1 
ATOM   7266  C CA  . ARG C 1 270 ? 141.395 106.765 126.386 1.00 59.62  ? 216 ARG C CA  1 
ATOM   7267  C C   . ARG C 1 270 ? 142.542 106.684 127.385 1.00 61.95  ? 216 ARG C C   1 
ATOM   7268  O O   . ARG C 1 270 ? 142.638 105.731 128.163 1.00 61.25  ? 216 ARG C O   1 
ATOM   7269  C CB  . ARG C 1 270 ? 140.102 107.154 127.099 1.00 54.70  ? 216 ARG C CB  1 
ATOM   7270  C CG  . ARG C 1 270 ? 140.137 108.534 127.722 1.00 54.43  ? 216 ARG C CG  1 
ATOM   7271  C CD  . ARG C 1 270 ? 138.828 108.847 128.415 1.00 53.77  ? 216 ARG C CD  1 
ATOM   7272  N NE  . ARG C 1 270 ? 137.684 108.609 127.545 1.00 53.96  ? 216 ARG C NE  1 
ATOM   7273  C CZ  . ARG C 1 270 ? 137.172 109.511 126.719 1.00 61.88  ? 216 ARG C CZ  1 
ATOM   7274  N NH1 . ARG C 1 270 ? 137.685 110.726 126.620 1.00 67.54  ? 216 ARG C NH1 1 
ATOM   7275  N NH2 . ARG C 1 270 ? 136.116 109.186 125.978 1.00 61.50  ? 216 ARG C NH2 1 
ATOM   7276  N N   . ASN C 1 271 ? 143.414 107.689 127.356 1.00 64.25  ? 217 ASN C N   1 
ATOM   7277  C CA  . ASN C 1 271 ? 144.484 107.786 128.339 1.00 63.25  ? 217 ASN C CA  1 
ATOM   7278  C C   . ASN C 1 271 ? 143.910 108.113 129.711 1.00 61.12  ? 217 ASN C C   1 
ATOM   7279  O O   . ASN C 1 271 ? 142.986 108.919 129.840 1.00 61.14  ? 217 ASN C O   1 
ATOM   7280  C CB  . ASN C 1 271 ? 145.496 108.852 127.922 1.00 61.82  ? 217 ASN C CB  1 
ATOM   7281  C CG  . ASN C 1 271 ? 146.104 108.577 126.563 1.00 67.73  ? 217 ASN C CG  1 
ATOM   7282  O OD1 . ASN C 1 271 ? 146.311 107.425 126.182 1.00 66.42  ? 217 ASN C OD1 1 
ATOM   7283  N ND2 . ASN C 1 271 ? 146.393 109.639 125.820 1.00 70.55  ? 217 ASN C ND2 1 
ATOM   7284  N N   . ILE C 1 272 ? 144.471 107.483 130.744 1.00 60.77  ? 218 ILE C N   1 
ATOM   7285  C CA  . ILE C 1 272 ? 143.918 107.581 132.091 1.00 59.87  ? 218 ILE C CA  1 
ATOM   7286  C C   . ILE C 1 272 ? 144.684 108.551 132.983 1.00 57.99  ? 218 ILE C C   1 
ATOM   7287  O O   . ILE C 1 272 ? 144.242 108.813 134.113 1.00 59.01  ? 218 ILE C O   1 
ATOM   7288  C CB  . ILE C 1 272 ? 143.853 106.187 132.754 1.00 56.97  ? 218 ILE C CB  1 
ATOM   7289  C CG1 . ILE C 1 272 ? 142.754 106.145 133.816 1.00 55.95  ? 218 ILE C CG1 1 
ATOM   7290  C CG2 . ILE C 1 272 ? 145.203 105.805 133.342 1.00 52.10  ? 218 ILE C CG2 1 
ATOM   7291  C CD1 . ILE C 1 272 ? 141.387 106.478 133.275 1.00 60.48  ? 218 ILE C CD1 1 
ATOM   7292  N N   . GLY C 1 273 ? 145.802 109.108 132.512 1.00 56.31  ? 219 GLY C N   1 
ATOM   7293  C CA  . GLY C 1 273 ? 146.607 109.965 133.368 1.00 53.24  ? 219 GLY C CA  1 
ATOM   7294  C C   . GLY C 1 273 ? 145.860 111.190 133.862 1.00 54.93  ? 219 GLY C C   1 
ATOM   7295  O O   . GLY C 1 273 ? 145.963 111.560 135.035 1.00 60.34  ? 219 GLY C O   1 
ATOM   7296  N N   . TYR C 1 274 ? 145.096 111.834 132.977 1.00 49.67  ? 220 TYR C N   1 
ATOM   7297  C CA  . TYR C 1 274 ? 144.352 113.026 133.370 1.00 51.48  ? 220 TYR C CA  1 
ATOM   7298  C C   . TYR C 1 274 ? 143.347 112.710 134.470 1.00 54.94  ? 220 TYR C C   1 
ATOM   7299  O O   . TYR C 1 274 ? 143.250 113.433 135.469 1.00 60.31  ? 220 TYR C O   1 
ATOM   7300  C CB  . TYR C 1 274 ? 143.650 113.625 132.151 1.00 51.76  ? 220 TYR C CB  1 
ATOM   7301  C CG  . TYR C 1 274 ? 142.652 114.712 132.478 1.00 56.29  ? 220 TYR C CG  1 
ATOM   7302  C CD1 . TYR C 1 274 ? 143.056 116.029 132.637 1.00 54.95  ? 220 TYR C CD1 1 
ATOM   7303  C CD2 . TYR C 1 274 ? 141.302 114.421 132.614 1.00 60.45  ? 220 TYR C CD2 1 
ATOM   7304  C CE1 . TYR C 1 274 ? 142.146 117.022 132.929 1.00 58.55  ? 220 TYR C CE1 1 
ATOM   7305  C CE2 . TYR C 1 274 ? 140.387 115.407 132.907 1.00 62.72  ? 220 TYR C CE2 1 
ATOM   7306  C CZ  . TYR C 1 274 ? 140.812 116.705 133.063 1.00 62.49  ? 220 TYR C CZ  1 
ATOM   7307  O OH  . TYR C 1 274 ? 139.898 117.689 133.355 1.00 70.47  ? 220 TYR C OH  1 
ATOM   7308  N N   . PHE C 1 275 ? 142.594 111.624 134.308 1.00 54.33  ? 221 PHE C N   1 
ATOM   7309  C CA  . PHE C 1 275 ? 141.580 111.276 135.293 1.00 55.56  ? 221 PHE C CA  1 
ATOM   7310  C C   . PHE C 1 275 ? 142.192 110.698 136.559 1.00 56.05  ? 221 PHE C C   1 
ATOM   7311  O O   . PHE C 1 275 ? 141.599 110.812 137.637 1.00 58.51  ? 221 PHE C O   1 
ATOM   7312  C CB  . PHE C 1 275 ? 140.579 110.302 134.680 1.00 54.67  ? 221 PHE C CB  1 
ATOM   7313  C CG  . PHE C 1 275 ? 139.968 110.801 133.408 1.00 54.83  ? 221 PHE C CG  1 
ATOM   7314  C CD1 . PHE C 1 275 ? 138.824 111.575 133.434 1.00 57.44  ? 221 PHE C CD1 1 
ATOM   7315  C CD2 . PHE C 1 275 ? 140.551 110.515 132.186 1.00 55.77  ? 221 PHE C CD2 1 
ATOM   7316  C CE1 . PHE C 1 275 ? 138.265 112.043 132.267 1.00 61.34  ? 221 PHE C CE1 1 
ATOM   7317  C CE2 . PHE C 1 275 ? 139.996 110.982 131.015 1.00 56.20  ? 221 PHE C CE2 1 
ATOM   7318  C CZ  . PHE C 1 275 ? 138.851 111.746 131.055 1.00 57.09  ? 221 PHE C CZ  1 
ATOM   7319  N N   . ILE C 1 276 ? 143.367 110.077 136.451 1.00 57.47  ? 222 ILE C N   1 
ATOM   7320  C CA  . ILE C 1 276 ? 144.091 109.658 137.646 1.00 52.88  ? 222 ILE C CA  1 
ATOM   7321  C C   . ILE C 1 276 ? 144.525 110.873 138.453 1.00 56.08  ? 222 ILE C C   1 
ATOM   7322  O O   . ILE C 1 276 ? 144.400 110.897 139.683 1.00 57.04  ? 222 ILE C O   1 
ATOM   7323  C CB  . ILE C 1 276 ? 145.287 108.770 137.260 1.00 49.24  ? 222 ILE C CB  1 
ATOM   7324  C CG1 . ILE C 1 276 ? 144.807 107.373 136.868 1.00 49.40  ? 222 ILE C CG1 1 
ATOM   7325  C CG2 . ILE C 1 276 ? 146.286 108.688 138.399 1.00 47.25  ? 222 ILE C CG2 1 
ATOM   7326  C CD1 . ILE C 1 276 ? 144.103 106.638 137.982 1.00 52.91  ? 222 ILE C CD1 1 
ATOM   7327  N N   . LEU C 1 277 ? 145.023 111.905 137.779 1.00 59.10  ? 223 LEU C N   1 
ATOM   7328  C CA  . LEU C 1 277 ? 145.516 113.106 138.440 1.00 59.26  ? 223 LEU C CA  1 
ATOM   7329  C C   . LEU C 1 277 ? 144.425 114.126 138.734 1.00 56.65  ? 223 LEU C C   1 
ATOM   7330  O O   . LEU C 1 277 ? 144.725 115.175 139.312 1.00 59.24  ? 223 LEU C O   1 
ATOM   7331  C CB  . LEU C 1 277 ? 146.600 113.765 137.586 1.00 60.22  ? 223 LEU C CB  1 
ATOM   7332  C CG  . LEU C 1 277 ? 147.841 112.917 137.317 1.00 69.82  ? 223 LEU C CG  1 
ATOM   7333  C CD1 . LEU C 1 277 ? 148.735 113.608 136.308 1.00 71.09  ? 223 LEU C CD1 1 
ATOM   7334  C CD2 . LEU C 1 277 ? 148.589 112.650 138.611 1.00 76.57  ? 223 LEU C CD2 1 
ATOM   7335  N N   . GLN C 1 278 ? 143.179 113.860 138.348 1.00 54.80  ? 224 GLN C N   1 
ATOM   7336  C CA  . GLN C 1 278 ? 142.137 114.860 138.531 1.00 54.05  ? 224 GLN C CA  1 
ATOM   7337  C C   . GLN C 1 278 ? 140.944 114.324 139.313 1.00 57.58  ? 224 GLN C C   1 
ATOM   7338  O O   . GLN C 1 278 ? 140.247 115.092 139.984 1.00 65.26  ? 224 GLN C O   1 
ATOM   7339  C CB  . GLN C 1 278 ? 141.677 115.390 137.173 1.00 56.02  ? 224 GLN C CB  1 
ATOM   7340  C CG  . GLN C 1 278 ? 141.381 116.875 137.165 1.00 64.15  ? 224 GLN C CG  1 
ATOM   7341  C CD  . GLN C 1 278 ? 142.600 117.705 137.508 1.00 67.60  ? 224 GLN C CD  1 
ATOM   7342  O OE1 . GLN C 1 278 ? 142.539 118.604 138.345 1.00 70.13  ? 224 GLN C OE1 1 
ATOM   7343  N NE2 . GLN C 1 278 ? 143.719 117.408 136.858 1.00 68.08  ? 224 GLN C NE2 1 
ATOM   7344  N N   . THR C 1 279 ? 140.691 113.019 139.235 1.00 58.33  ? 225 THR C N   1 
ATOM   7345  C CA  . THR C 1 279 ? 139.531 112.433 139.895 1.00 57.18  ? 225 THR C CA  1 
ATOM   7346  C C   . THR C 1 279 ? 139.892 111.396 140.946 1.00 58.50  ? 225 THR C C   1 
ATOM   7347  O O   . THR C 1 279 ? 139.494 111.537 142.108 1.00 61.50  ? 225 THR C O   1 
ATOM   7348  C CB  . THR C 1 279 ? 138.599 111.802 138.851 1.00 60.51  ? 225 THR C CB  1 
ATOM   7349  O OG1 . THR C 1 279 ? 139.347 110.897 138.031 1.00 63.67  ? 225 THR C OG1 1 
ATOM   7350  C CG2 . THR C 1 279 ? 137.978 112.875 137.977 1.00 64.97  ? 225 THR C CG2 1 
ATOM   7351  N N   . TYR C 1 280 ? 140.640 110.355 140.576 1.00 56.87  ? 226 TYR C N   1 
ATOM   7352  C CA  . TYR C 1 280 ? 140.845 109.230 141.485 1.00 59.76  ? 226 TYR C CA  1 
ATOM   7353  C C   . TYR C 1 280 ? 141.751 109.605 142.652 1.00 61.34  ? 226 TYR C C   1 
ATOM   7354  O O   . TYR C 1 280 ? 141.430 109.325 143.814 1.00 63.28  ? 226 TYR C O   1 
ATOM   7355  C CB  . TYR C 1 280 ? 141.412 108.037 140.718 1.00 58.53  ? 226 TYR C CB  1 
ATOM   7356  C CG  . TYR C 1 280 ? 140.479 107.520 139.649 1.00 56.95  ? 226 TYR C CG  1 
ATOM   7357  C CD1 . TYR C 1 280 ? 139.429 106.674 139.971 1.00 55.58  ? 226 TYR C CD1 1 
ATOM   7358  C CD2 . TYR C 1 280 ? 140.645 107.882 138.321 1.00 56.56  ? 226 TYR C CD2 1 
ATOM   7359  C CE1 . TYR C 1 280 ? 138.573 106.202 139.001 1.00 57.02  ? 226 TYR C CE1 1 
ATOM   7360  C CE2 . TYR C 1 280 ? 139.792 107.413 137.344 1.00 57.21  ? 226 TYR C CE2 1 
ATOM   7361  C CZ  . TYR C 1 280 ? 138.758 106.573 137.690 1.00 57.98  ? 226 TYR C CZ  1 
ATOM   7362  O OH  . TYR C 1 280 ? 137.904 106.102 136.722 1.00 57.94  ? 226 TYR C OH  1 
ATOM   7363  N N   . MET C 1 281 ? 142.892 110.231 142.364 1.00 60.93  ? 227 MET C N   1 
ATOM   7364  C CA  . MET C 1 281 ? 143.811 110.610 143.436 1.00 59.56  ? 227 MET C CA  1 
ATOM   7365  C C   . MET C 1 281 ? 143.198 111.610 144.409 1.00 60.94  ? 227 MET C C   1 
ATOM   7366  O O   . MET C 1 281 ? 143.314 111.397 145.630 1.00 65.09  ? 227 MET C O   1 
ATOM   7367  C CB  . MET C 1 281 ? 145.117 111.146 142.838 1.00 58.56  ? 227 MET C CB  1 
ATOM   7368  C CG  . MET C 1 281 ? 146.163 111.507 143.878 1.00 68.25  ? 227 MET C CG  1 
ATOM   7369  S SD  . MET C 1 281 ? 147.309 112.782 143.323 1.00 95.47  ? 227 MET C SD  1 
ATOM   7370  C CE  . MET C 1 281 ? 146.243 114.218 143.331 1.00 55.82  ? 227 MET C CE  1 
ATOM   7371  N N   . PRO C 1 282 ? 142.572 112.711 143.967 1.00 57.02  ? 228 PRO C N   1 
ATOM   7372  C CA  . PRO C 1 282 ? 141.923 113.596 144.946 1.00 59.90  ? 228 PRO C CA  1 
ATOM   7373  C C   . PRO C 1 282 ? 140.846 112.900 145.754 1.00 62.88  ? 228 PRO C C   1 
ATOM   7374  O O   . PRO C 1 282 ? 140.717 113.165 146.952 1.00 66.49  ? 228 PRO C O   1 
ATOM   7375  C CB  . PRO C 1 282 ? 141.347 114.720 144.073 1.00 57.68  ? 228 PRO C CB  1 
ATOM   7376  C CG  . PRO C 1 282 ? 142.162 114.699 142.843 1.00 56.41  ? 228 PRO C CG  1 
ATOM   7377  C CD  . PRO C 1 282 ? 142.465 113.257 142.603 1.00 57.43  ? 228 PRO C CD  1 
ATOM   7378  N N   . SER C 1 283 ? 140.074 112.004 145.135 1.00 62.59  ? 229 SER C N   1 
ATOM   7379  C CA  . SER C 1 283 ? 139.026 111.304 145.871 1.00 65.47  ? 229 SER C CA  1 
ATOM   7380  C C   . SER C 1 283 ? 139.615 110.405 146.951 1.00 66.01  ? 229 SER C C   1 
ATOM   7381  O O   . SER C 1 283 ? 139.112 110.369 148.082 1.00 66.97  ? 229 SER C O   1 
ATOM   7382  C CB  . SER C 1 283 ? 138.163 110.494 144.907 1.00 61.79  ? 229 SER C CB  1 
ATOM   7383  O OG  . SER C 1 283 ? 137.712 111.303 143.837 1.00 64.42  ? 229 SER C OG  1 
ATOM   7384  N N   . ILE C 1 284 ? 140.687 109.679 146.625 1.00 59.75  ? 230 ILE C N   1 
ATOM   7385  C CA  . ILE C 1 284 ? 141.336 108.830 147.619 1.00 58.24  ? 230 ILE C CA  1 
ATOM   7386  C C   . ILE C 1 284 ? 141.903 109.674 148.753 1.00 64.33  ? 230 ILE C C   1 
ATOM   7387  O O   . ILE C 1 284 ? 141.770 109.326 149.937 1.00 67.33  ? 230 ILE C O   1 
ATOM   7388  C CB  . ILE C 1 284 ? 142.424 107.966 146.957 1.00 56.52  ? 230 ILE C CB  1 
ATOM   7389  C CG1 . ILE C 1 284 ? 141.799 107.012 145.939 1.00 57.99  ? 230 ILE C CG1 1 
ATOM   7390  C CG2 . ILE C 1 284 ? 143.191 107.188 148.007 1.00 57.89  ? 230 ILE C CG2 1 
ATOM   7391  C CD1 . ILE C 1 284 ? 142.811 106.220 145.144 1.00 62.34  ? 230 ILE C CD1 1 
ATOM   7392  N N   . LEU C 1 285 ? 142.545 110.796 148.415 1.00 62.17  ? 231 LEU C N   1 
ATOM   7393  C CA  . LEU C 1 285 ? 143.096 111.662 149.452 1.00 61.36  ? 231 LEU C CA  1 
ATOM   7394  C C   . LEU C 1 285 ? 142.000 112.209 150.356 1.00 64.12  ? 231 LEU C C   1 
ATOM   7395  O O   . LEU C 1 285 ? 142.166 112.265 151.579 1.00 68.88  ? 231 LEU C O   1 
ATOM   7396  C CB  . LEU C 1 285 ? 143.890 112.805 148.824 1.00 58.02  ? 231 LEU C CB  1 
ATOM   7397  C CG  . LEU C 1 285 ? 145.229 112.423 148.196 1.00 60.75  ? 231 LEU C CG  1 
ATOM   7398  C CD1 . LEU C 1 285 ? 146.027 113.669 147.855 1.00 64.25  ? 231 LEU C CD1 1 
ATOM   7399  C CD2 . LEU C 1 285 ? 146.015 111.518 149.128 1.00 58.45  ? 231 LEU C CD2 1 
ATOM   7400  N N   . ILE C 1 286 ? 140.873 112.620 149.773 1.00 59.93  ? 232 ILE C N   1 
ATOM   7401  C CA  . ILE C 1 286 ? 139.775 113.153 150.573 1.00 58.35  ? 232 ILE C CA  1 
ATOM   7402  C C   . ILE C 1 286 ? 139.209 112.074 151.485 1.00 61.63  ? 232 ILE C C   1 
ATOM   7403  O O   . ILE C 1 286 ? 138.880 112.335 152.647 1.00 68.30  ? 232 ILE C O   1 
ATOM   7404  C CB  . ILE C 1 286 ? 138.693 113.762 149.663 1.00 57.36  ? 232 ILE C CB  1 
ATOM   7405  C CG1 . ILE C 1 286 ? 139.243 114.986 148.932 1.00 57.92  ? 232 ILE C CG1 1 
ATOM   7406  C CG2 . ILE C 1 286 ? 137.474 114.157 150.468 1.00 61.51  ? 232 ILE C CG2 1 
ATOM   7407  C CD1 . ILE C 1 286 ? 139.816 116.030 149.852 1.00 67.58  ? 232 ILE C CD1 1 
ATOM   7408  N N   . THR C 1 287 ? 139.096 110.842 150.982 1.00 57.24  ? 233 THR C N   1 
ATOM   7409  C CA  . THR C 1 287 ? 138.605 109.754 151.825 1.00 62.08  ? 233 THR C CA  1 
ATOM   7410  C C   . THR C 1 287 ? 139.545 109.493 153.000 1.00 63.29  ? 233 THR C C   1 
ATOM   7411  O O   . THR C 1 287 ? 139.096 109.289 154.136 1.00 63.12  ? 233 THR C O   1 
ATOM   7412  C CB  . THR C 1 287 ? 138.418 108.487 150.992 1.00 63.09  ? 233 THR C CB  1 
ATOM   7413  O OG1 . THR C 1 287 ? 137.627 108.790 149.838 1.00 63.06  ? 233 THR C OG1 1 
ATOM   7414  C CG2 . THR C 1 287 ? 137.710 107.421 151.805 1.00 59.15  ? 233 THR C CG2 1 
ATOM   7415  N N   . ILE C 1 288 ? 140.856 109.505 152.750 1.00 61.41  ? 234 ILE C N   1 
ATOM   7416  C CA  . ILE C 1 288 ? 141.811 109.287 153.837 1.00 64.73  ? 234 ILE C CA  1 
ATOM   7417  C C   . ILE C 1 288 ? 141.742 110.425 154.854 1.00 67.48  ? 234 ILE C C   1 
ATOM   7418  O O   . ILE C 1 288 ? 141.750 110.197 156.074 1.00 70.14  ? 234 ILE C O   1 
ATOM   7419  C CB  . ILE C 1 288 ? 143.233 109.111 153.272 1.00 62.59  ? 234 ILE C CB  1 
ATOM   7420  C CG1 . ILE C 1 288 ? 143.280 107.913 152.323 1.00 59.89  ? 234 ILE C CG1 1 
ATOM   7421  C CG2 . ILE C 1 288 ? 144.233 108.926 154.400 1.00 64.77  ? 234 ILE C CG2 1 
ATOM   7422  C CD1 . ILE C 1 288 ? 144.602 107.749 151.608 1.00 61.37  ? 234 ILE C CD1 1 
ATOM   7423  N N   . LEU C 1 289 ? 141.676 111.668 154.373 1.00 62.11  ? 235 LEU C N   1 
ATOM   7424  C CA  . LEU C 1 289 ? 141.598 112.800 155.289 1.00 58.63  ? 235 LEU C CA  1 
ATOM   7425  C C   . LEU C 1 289 ? 140.278 112.815 156.051 1.00 63.03  ? 235 LEU C C   1 
ATOM   7426  O O   . LEU C 1 289 ? 140.200 113.392 157.141 1.00 69.15  ? 235 LEU C O   1 
ATOM   7427  C CB  . LEU C 1 289 ? 141.805 114.107 154.525 1.00 56.62  ? 235 LEU C CB  1 
ATOM   7428  C CG  . LEU C 1 289 ? 143.159 114.204 153.813 1.00 59.75  ? 235 LEU C CG  1 
ATOM   7429  C CD1 . LEU C 1 289 ? 143.339 115.541 153.111 1.00 65.94  ? 235 LEU C CD1 1 
ATOM   7430  C CD2 . LEU C 1 289 ? 144.299 113.948 154.786 1.00 60.33  ? 235 LEU C CD2 1 
ATOM   7431  N N   . SER C 1 290 ? 139.234 112.197 155.496 1.00 63.08  ? 236 SER C N   1 
ATOM   7432  C CA  . SER C 1 290 ? 138.003 112.008 156.255 1.00 62.64  ? 236 SER C CA  1 
ATOM   7433  C C   . SER C 1 290 ? 138.181 110.943 157.328 1.00 65.58  ? 236 SER C C   1 
ATOM   7434  O O   . SER C 1 290 ? 137.643 111.070 158.433 1.00 69.57  ? 236 SER C O   1 
ATOM   7435  C CB  . SER C 1 290 ? 136.855 111.637 155.319 1.00 63.61  ? 236 SER C CB  1 
ATOM   7436  O OG  . SER C 1 290 ? 137.034 110.334 154.794 1.00 66.97  ? 236 SER C OG  1 
ATOM   7437  N N   . TRP C 1 291 ? 138.924 109.876 157.014 1.00 71.36  ? 237 TRP C N   1 
ATOM   7438  C CA  . TRP C 1 291 ? 139.261 108.889 158.038 1.00 72.85  ? 237 TRP C CA  1 
ATOM   7439  C C   . TRP C 1 291 ? 140.028 109.522 159.186 1.00 69.04  ? 237 TRP C C   1 
ATOM   7440  O O   . TRP C 1 291 ? 139.915 109.074 160.333 1.00 66.93  ? 237 TRP C O   1 
ATOM   7441  C CB  . TRP C 1 291 ? 140.111 107.762 157.459 1.00 73.67  ? 237 TRP C CB  1 
ATOM   7442  C CG  . TRP C 1 291 ? 139.511 107.021 156.336 1.00 71.04  ? 237 TRP C CG  1 
ATOM   7443  C CD1 . TRP C 1 291 ? 138.195 106.957 155.999 1.00 73.36  ? 237 TRP C CD1 1 
ATOM   7444  C CD2 . TRP C 1 291 ? 140.214 106.227 155.382 1.00 68.75  ? 237 TRP C CD2 1 
ATOM   7445  N NE1 . TRP C 1 291 ? 138.033 106.166 154.888 1.00 74.82  ? 237 TRP C NE1 1 
ATOM   7446  C CE2 . TRP C 1 291 ? 139.261 105.707 154.491 1.00 71.38  ? 237 TRP C CE2 1 
ATOM   7447  C CE3 . TRP C 1 291 ? 141.561 105.906 155.195 1.00 70.08  ? 237 TRP C CE3 1 
ATOM   7448  C CZ2 . TRP C 1 291 ? 139.611 104.885 153.430 1.00 71.06  ? 237 TRP C CZ2 1 
ATOM   7449  C CZ3 . TRP C 1 291 ? 141.905 105.089 154.142 1.00 73.27  ? 237 TRP C CZ3 1 
ATOM   7450  C CH2 . TRP C 1 291 ? 140.935 104.586 153.272 1.00 72.51  ? 237 TRP C CH2 1 
ATOM   7451  N N   . VAL C 1 292 ? 140.834 110.543 158.884 1.00 69.52  ? 238 VAL C N   1 
ATOM   7452  C CA  . VAL C 1 292 ? 141.691 111.175 159.889 1.00 71.28  ? 238 VAL C CA  1 
ATOM   7453  C C   . VAL C 1 292 ? 140.912 111.565 161.140 1.00 69.38  ? 238 VAL C C   1 
ATOM   7454  O O   . VAL C 1 292 ? 141.445 111.508 162.255 1.00 72.75  ? 238 VAL C O   1 
ATOM   7455  C CB  . VAL C 1 292 ? 142.412 112.389 159.264 1.00 67.46  ? 238 VAL C CB  1 
ATOM   7456  C CG1 . VAL C 1 292 ? 143.046 113.261 160.332 1.00 63.36  ? 238 VAL C CG1 1 
ATOM   7457  C CG2 . VAL C 1 292 ? 143.466 111.919 158.277 1.00 67.78  ? 238 VAL C CG2 1 
ATOM   7458  N N   . SER C 1 293 ? 139.637 111.932 160.989 1.00 67.67  ? 239 SER C N   1 
ATOM   7459  C CA  . SER C 1 293 ? 138.855 112.409 162.127 1.00 69.04  ? 239 SER C CA  1 
ATOM   7460  C C   . SER C 1 293 ? 138.626 111.336 163.185 1.00 79.71  ? 239 SER C C   1 
ATOM   7461  O O   . SER C 1 293 ? 138.273 111.673 164.320 1.00 84.45  ? 239 SER C O   1 
ATOM   7462  C CB  . SER C 1 293 ? 137.506 112.948 161.651 1.00 67.55  ? 239 SER C CB  1 
ATOM   7463  O OG  . SER C 1 293 ? 136.651 111.896 161.241 1.00 66.98  ? 239 SER C OG  1 
ATOM   7464  N N   . PHE C 1 294 ? 138.814 110.058 162.846 1.00 82.28  ? 240 PHE C N   1 
ATOM   7465  C CA  . PHE C 1 294 ? 138.535 108.989 163.802 1.00 82.04  ? 240 PHE C CA  1 
ATOM   7466  C C   . PHE C 1 294 ? 139.480 109.026 164.996 1.00 82.80  ? 240 PHE C C   1 
ATOM   7467  O O   . PHE C 1 294 ? 139.108 108.586 166.090 1.00 82.29  ? 240 PHE C O   1 
ATOM   7468  C CB  . PHE C 1 294 ? 138.611 107.633 163.105 1.00 78.03  ? 240 PHE C CB  1 
ATOM   7469  C CG  . PHE C 1 294 ? 137.545 107.428 162.073 1.00 79.12  ? 240 PHE C CG  1 
ATOM   7470  C CD1 . PHE C 1 294 ? 136.265 107.911 162.281 1.00 78.83  ? 240 PHE C CD1 1 
ATOM   7471  C CD2 . PHE C 1 294 ? 137.823 106.765 160.891 1.00 82.07  ? 240 PHE C CD2 1 
ATOM   7472  C CE1 . PHE C 1 294 ? 135.279 107.729 161.334 1.00 80.19  ? 240 PHE C CE1 1 
ATOM   7473  C CE2 . PHE C 1 294 ? 136.842 106.582 159.938 1.00 81.84  ? 240 PHE C CE2 1 
ATOM   7474  C CZ  . PHE C 1 294 ? 135.568 107.065 160.160 1.00 81.38  ? 240 PHE C CZ  1 
ATOM   7475  N N   . TRP C 1 295 ? 140.696 109.536 164.812 1.00 81.51  ? 241 TRP C N   1 
ATOM   7476  C CA  . TRP C 1 295 ? 141.642 109.649 165.914 1.00 84.63  ? 241 TRP C CA  1 
ATOM   7477  C C   . TRP C 1 295 ? 141.388 110.868 166.791 1.00 87.40  ? 241 TRP C C   1 
ATOM   7478  O O   . TRP C 1 295 ? 141.971 110.960 167.877 1.00 86.89  ? 241 TRP C O   1 
ATOM   7479  C CB  . TRP C 1 295 ? 143.073 109.688 165.376 1.00 81.50  ? 241 TRP C CB  1 
ATOM   7480  C CG  . TRP C 1 295 ? 143.600 108.341 164.983 1.00 85.94  ? 241 TRP C CG  1 
ATOM   7481  C CD1 . TRP C 1 295 ? 144.351 107.499 165.751 1.00 92.37  ? 241 TRP C CD1 1 
ATOM   7482  C CD2 . TRP C 1 295 ? 143.413 107.676 163.727 1.00 86.70  ? 241 TRP C CD2 1 
ATOM   7483  N NE1 . TRP C 1 295 ? 144.645 106.355 165.052 1.00 90.13  ? 241 TRP C NE1 1 
ATOM   7484  C CE2 . TRP C 1 295 ? 144.081 106.438 163.807 1.00 88.31  ? 241 TRP C CE2 1 
ATOM   7485  C CE3 . TRP C 1 295 ? 142.747 108.008 162.544 1.00 85.17  ? 241 TRP C CE3 1 
ATOM   7486  C CZ2 . TRP C 1 295 ? 144.102 105.532 162.749 1.00 88.18  ? 241 TRP C CZ2 1 
ATOM   7487  C CZ3 . TRP C 1 295 ? 142.769 107.107 161.495 1.00 86.25  ? 241 TRP C CZ3 1 
ATOM   7488  C CH2 . TRP C 1 295 ? 143.442 105.884 161.605 1.00 87.80  ? 241 TRP C CH2 1 
ATOM   7489  N N   . ILE C 1 296 ? 140.546 111.797 166.355 1.00 84.05  ? 242 ILE C N   1 
ATOM   7490  C CA  . ILE C 1 296 ? 140.216 112.968 167.157 1.00 79.24  ? 242 ILE C CA  1 
ATOM   7491  C C   . ILE C 1 296 ? 139.233 112.564 168.247 1.00 85.47  ? 242 ILE C C   1 
ATOM   7492  O O   . ILE C 1 296 ? 138.400 111.670 168.063 1.00 87.83  ? 242 ILE C O   1 
ATOM   7493  C CB  . ILE C 1 296 ? 139.649 114.092 166.268 1.00 78.90  ? 242 ILE C CB  1 
ATOM   7494  C CG1 . ILE C 1 296 ? 140.517 114.276 165.024 1.00 81.53  ? 242 ILE C CG1 1 
ATOM   7495  C CG2 . ILE C 1 296 ? 139.575 115.400 167.036 1.00 79.97  ? 242 ILE C CG2 1 
ATOM   7496  C CD1 . ILE C 1 296 ? 141.934 114.697 165.328 1.00 82.98  ? 242 ILE C CD1 1 
ATOM   7497  N N   . ASN C 1 297 ? 139.337 113.220 169.401 1.00 89.81  ? 243 ASN C N   1 
ATOM   7498  C CA  . ASN C 1 297 ? 138.446 112.917 170.511 1.00 89.51  ? 243 ASN C CA  1 
ATOM   7499  C C   . ASN C 1 297 ? 137.008 113.277 170.156 1.00 93.48  ? 243 ASN C C   1 
ATOM   7500  O O   . ASN C 1 297 ? 136.745 114.205 169.387 1.00 96.66  ? 243 ASN C O   1 
ATOM   7501  C CB  . ASN C 1 297 ? 138.882 113.668 171.768 1.00 85.97  ? 243 ASN C CB  1 
ATOM   7502  C CG  . ASN C 1 297 ? 138.085 113.264 172.992 1.00 96.27  ? 243 ASN C CG  1 
ATOM   7503  O OD1 . ASN C 1 297 ? 137.450 112.210 173.011 1.00 100.99 ? 243 ASN C OD1 1 
ATOM   7504  N ND2 . ASN C 1 297 ? 138.115 114.101 174.022 1.00 103.39 ? 243 ASN C ND2 1 
ATOM   7505  N N   . TYR C 1 298 ? 136.068 112.521 170.729 1.00 98.14  ? 244 TYR C N   1 
ATOM   7506  C CA  . TYR C 1 298 ? 134.655 112.725 170.436 1.00 99.01  ? 244 TYR C CA  1 
ATOM   7507  C C   . TYR C 1 298 ? 134.148 114.085 170.897 1.00 98.22  ? 244 TYR C C   1 
ATOM   7508  O O   . TYR C 1 298 ? 133.137 114.564 170.373 1.00 95.44  ? 244 TYR C O   1 
ATOM   7509  C CB  . TYR C 1 298 ? 133.826 111.618 171.087 1.00 101.88 ? 244 TYR C CB  1 
ATOM   7510  C CG  . TYR C 1 298 ? 134.342 111.198 172.443 1.00 105.93 ? 244 TYR C CG  1 
ATOM   7511  C CD1 . TYR C 1 298 ? 134.142 111.996 173.562 1.00 109.63 ? 244 TYR C CD1 1 
ATOM   7512  C CD2 . TYR C 1 298 ? 135.033 110.006 172.605 1.00 106.42 ? 244 TYR C CD2 1 
ATOM   7513  C CE1 . TYR C 1 298 ? 134.618 111.618 174.803 1.00 112.67 ? 244 TYR C CE1 1 
ATOM   7514  C CE2 . TYR C 1 298 ? 135.510 109.619 173.842 1.00 117.14 ? 244 TYR C CE2 1 
ATOM   7515  C CZ  . TYR C 1 298 ? 135.299 110.428 174.938 1.00 118.77 ? 244 TYR C CZ  1 
ATOM   7516  O OH  . TYR C 1 298 ? 135.772 110.046 176.172 1.00 119.17 ? 244 TYR C OH  1 
ATOM   7517  N N   . ASP C 1 299 ? 134.816 114.714 171.865 1.00 100.91 ? 245 ASP C N   1 
ATOM   7518  C CA  . ASP C 1 299 ? 134.349 116.004 172.360 1.00 99.37  ? 245 ASP C CA  1 
ATOM   7519  C C   . ASP C 1 299 ? 134.678 117.141 171.401 1.00 93.79  ? 245 ASP C C   1 
ATOM   7520  O O   . ASP C 1 299 ? 133.991 118.167 171.408 1.00 90.26  ? 245 ASP C O   1 
ATOM   7521  C CB  . ASP C 1 299 ? 134.944 116.291 173.740 1.00 98.29  ? 245 ASP C CB  1 
ATOM   7522  C CG  . ASP C 1 299 ? 136.388 116.743 173.672 1.00 102.95 ? 245 ASP C CG  1 
ATOM   7523  O OD1 . ASP C 1 299 ? 137.148 116.204 172.841 1.00 104.51 ? 245 ASP C OD1 1 
ATOM   7524  O OD2 . ASP C 1 299 ? 136.764 117.645 174.451 1.00 103.98 ? 245 ASP C OD2 1 
ATOM   7525  N N   . ALA C 1 300 ? 135.712 116.981 170.577 1.00 90.98  ? 246 ALA C N   1 
ATOM   7526  C CA  . ALA C 1 300 ? 136.140 118.038 169.669 1.00 84.77  ? 246 ALA C CA  1 
ATOM   7527  C C   . ALA C 1 300 ? 135.184 118.155 168.489 1.00 85.75  ? 246 ALA C C   1 
ATOM   7528  O O   . ALA C 1 300 ? 135.540 117.816 167.356 1.00 85.53  ? 246 ALA C O   1 
ATOM   7529  C CB  . ALA C 1 300 ? 137.564 117.781 169.178 1.00 85.59  ? 246 ALA C CB  1 
ATOM   7530  N N   . SER C 1 301 ? 133.965 118.632 168.754 1.00 89.19  ? 247 SER C N   1 
ATOM   7531  C CA  . SER C 1 301 ? 132.939 118.674 167.718 1.00 84.22  ? 247 SER C CA  1 
ATOM   7532  C C   . SER C 1 301 ? 133.330 119.598 166.574 1.00 78.60  ? 247 SER C C   1 
ATOM   7533  O O   . SER C 1 301 ? 133.111 119.270 165.401 1.00 75.26  ? 247 SER C O   1 
ATOM   7534  C CB  . SER C 1 301 ? 131.605 119.104 168.326 1.00 81.78  ? 247 SER C CB  1 
ATOM   7535  O OG  . SER C 1 301 ? 131.739 120.330 169.022 1.00 88.67  ? 247 SER C OG  1 
ATOM   7536  N N   . ALA C 1 302 ? 133.912 120.755 166.892 1.00 79.34  ? 248 ALA C N   1 
ATOM   7537  C CA  . ALA C 1 302 ? 134.247 121.724 165.853 1.00 78.07  ? 248 ALA C CA  1 
ATOM   7538  C C   . ALA C 1 302 ? 135.192 121.121 164.822 1.00 77.60  ? 248 ALA C C   1 
ATOM   7539  O O   . ALA C 1 302 ? 134.914 121.154 163.618 1.00 76.71  ? 248 ALA C O   1 
ATOM   7540  C CB  . ALA C 1 302 ? 134.862 122.974 166.482 1.00 81.39  ? 248 ALA C CB  1 
ATOM   7541  N N   . ALA C 1 303 ? 136.300 120.534 165.280 1.00 77.37  ? 249 ALA C N   1 
ATOM   7542  C CA  . ALA C 1 303 ? 137.309 120.029 164.354 1.00 71.39  ? 249 ALA C CA  1 
ATOM   7543  C C   . ALA C 1 303 ? 136.785 118.859 163.531 1.00 74.70  ? 249 ALA C C   1 
ATOM   7544  O O   . ALA C 1 303 ? 136.977 118.820 162.310 1.00 77.95  ? 249 ALA C O   1 
ATOM   7545  C CB  . ALA C 1 303 ? 138.565 119.623 165.120 1.00 72.04  ? 249 ALA C CB  1 
ATOM   7546  N N   . ARG C 1 304 ? 136.123 117.897 164.176 1.00 74.70  ? 250 ARG C N   1 
ATOM   7547  C CA  . ARG C 1 304 ? 135.644 116.723 163.451 1.00 69.84  ? 250 ARG C CA  1 
ATOM   7548  C C   . ARG C 1 304 ? 134.558 117.092 162.449 1.00 72.78  ? 250 ARG C C   1 
ATOM   7549  O O   . ARG C 1 304 ? 134.564 116.607 161.309 1.00 74.07  ? 250 ARG C O   1 
ATOM   7550  C CB  . ARG C 1 304 ? 135.132 115.671 164.431 1.00 69.14  ? 250 ARG C CB  1 
ATOM   7551  C CG  . ARG C 1 304 ? 136.180 115.187 165.411 1.00 77.47  ? 250 ARG C CG  1 
ATOM   7552  C CD  . ARG C 1 304 ? 135.793 113.845 165.997 1.00 80.52  ? 250 ARG C CD  1 
ATOM   7553  N NE  . ARG C 1 304 ? 135.638 112.833 164.960 1.00 81.79  ? 250 ARG C NE  1 
ATOM   7554  C CZ  . ARG C 1 304 ? 135.305 111.571 165.190 1.00 84.56  ? 250 ARG C CZ  1 
ATOM   7555  N NH1 . ARG C 1 304 ? 135.077 111.130 166.416 1.00 87.51  ? 250 ARG C NH1 1 
ATOM   7556  N NH2 . ARG C 1 304 ? 135.198 110.731 164.165 1.00 80.64  ? 250 ARG C NH2 1 
ATOM   7557  N N   . VAL C 1 305 ? 133.619 117.949 162.851 1.00 70.86  ? 251 VAL C N   1 
ATOM   7558  C CA  . VAL C 1 305 ? 132.556 118.345 161.937 1.00 69.70  ? 251 VAL C CA  1 
ATOM   7559  C C   . VAL C 1 305 ? 133.120 119.180 160.794 1.00 68.14  ? 251 VAL C C   1 
ATOM   7560  O O   . VAL C 1 305 ? 132.672 119.064 159.649 1.00 69.02  ? 251 VAL C O   1 
ATOM   7561  C CB  . VAL C 1 305 ? 131.442 119.080 162.700 1.00 64.88  ? 251 VAL C CB  1 
ATOM   7562  C CG1 . VAL C 1 305 ? 130.438 119.675 161.739 1.00 64.46  ? 251 VAL C CG1 1 
ATOM   7563  C CG2 . VAL C 1 305 ? 130.741 118.120 163.641 1.00 70.40  ? 251 VAL C CG2 1 
ATOM   7564  N N   . ALA C 1 306 ? 134.121 120.019 161.074 1.00 63.58  ? 252 ALA C N   1 
ATOM   7565  C CA  . ALA C 1 306 ? 134.773 120.772 160.010 1.00 61.97  ? 252 ALA C CA  1 
ATOM   7566  C C   . ALA C 1 306 ? 135.454 119.835 159.021 1.00 69.05  ? 252 ALA C C   1 
ATOM   7567  O O   . ALA C 1 306 ? 135.366 120.025 157.802 1.00 74.72  ? 252 ALA C O   1 
ATOM   7568  C CB  . ALA C 1 306 ? 135.779 121.756 160.607 1.00 60.06  ? 252 ALA C CB  1 
ATOM   7569  N N   . LEU C 1 307 ? 136.139 118.810 159.534 1.00 64.57  ? 253 LEU C N   1 
ATOM   7570  C CA  . LEU C 1 307 ? 136.764 117.817 158.666 1.00 62.51  ? 253 LEU C CA  1 
ATOM   7571  C C   . LEU C 1 307 ? 135.730 117.147 157.774 1.00 69.49  ? 253 LEU C C   1 
ATOM   7572  O O   . LEU C 1 307 ? 135.914 117.039 156.554 1.00 76.61  ? 253 LEU C O   1 
ATOM   7573  C CB  . LEU C 1 307 ? 137.495 116.770 159.508 1.00 58.61  ? 253 LEU C CB  1 
ATOM   7574  C CG  . LEU C 1 307 ? 138.927 117.083 159.937 1.00 60.34  ? 253 LEU C CG  1 
ATOM   7575  C CD1 . LEU C 1 307 ? 139.433 116.027 160.906 1.00 62.37  ? 253 LEU C CD1 1 
ATOM   7576  C CD2 . LEU C 1 307 ? 139.824 117.163 158.717 1.00 55.96  ? 253 LEU C CD2 1 
ATOM   7577  N N   . GLY C 1 308 ? 134.628 116.698 158.369 1.00 61.36  ? 254 GLY C N   1 
ATOM   7578  C CA  . GLY C 1 308 ? 133.580 116.048 157.610 1.00 64.71  ? 254 GLY C CA  1 
ATOM   7579  C C   . GLY C 1 308 ? 132.991 116.938 156.535 1.00 70.61  ? 254 GLY C C   1 
ATOM   7580  O O   . GLY C 1 308 ? 132.843 116.521 155.381 1.00 72.77  ? 254 GLY C O   1 
ATOM   7581  N N   . ILE C 1 309 ? 132.666 118.179 156.907 1.00 67.03  ? 255 ILE C N   1 
ATOM   7582  C CA  . ILE C 1 309 ? 132.050 119.108 155.964 1.00 63.83  ? 255 ILE C CA  1 
ATOM   7583  C C   . ILE C 1 309 ? 133.002 119.407 154.815 1.00 66.73  ? 255 ILE C C   1 
ATOM   7584  O O   . ILE C 1 309 ? 132.608 119.401 153.643 1.00 71.39  ? 255 ILE C O   1 
ATOM   7585  C CB  . ILE C 1 309 ? 131.623 120.399 156.682 1.00 59.99  ? 255 ILE C CB  1 
ATOM   7586  C CG1 . ILE C 1 309 ? 130.514 120.118 157.691 1.00 61.91  ? 255 ILE C CG1 1 
ATOM   7587  C CG2 . ILE C 1 309 ? 131.164 121.437 155.677 1.00 63.65  ? 255 ILE C CG2 1 
ATOM   7588  C CD1 . ILE C 1 309 ? 130.214 121.301 158.573 1.00 64.25  ? 255 ILE C CD1 1 
ATOM   7589  N N   . THR C 1 310 ? 134.268 119.687 155.135 1.00 63.88  ? 256 THR C N   1 
ATOM   7590  C CA  . THR C 1 310 ? 135.242 120.000 154.097 1.00 66.36  ? 256 THR C CA  1 
ATOM   7591  C C   . THR C 1 310 ? 135.420 118.825 153.146 1.00 69.39  ? 256 THR C C   1 
ATOM   7592  O O   . THR C 1 310 ? 135.446 118.998 151.923 1.00 69.13  ? 256 THR C O   1 
ATOM   7593  C CB  . THR C 1 310 ? 136.578 120.391 154.730 1.00 64.64  ? 256 THR C CB  1 
ATOM   7594  O OG1 . THR C 1 310 ? 136.723 119.731 155.992 1.00 69.28  ? 256 THR C OG1 1 
ATOM   7595  C CG2 . THR C 1 310 ? 136.649 121.892 154.934 1.00 72.73  ? 256 THR C CG2 1 
ATOM   7596  N N   . THR C 1 311 ? 135.530 117.611 153.692 1.00 68.23  ? 257 THR C N   1 
ATOM   7597  C CA  . THR C 1 311 ? 135.714 116.441 152.839 1.00 69.64  ? 257 THR C CA  1 
ATOM   7598  C C   . THR C 1 311 ? 134.506 116.221 151.935 1.00 73.67  ? 257 THR C C   1 
ATOM   7599  O O   . THR C 1 311 ? 134.654 115.966 150.733 1.00 75.61  ? 257 THR C O   1 
ATOM   7600  C CB  . THR C 1 311 ? 135.987 115.205 153.696 1.00 66.41  ? 257 THR C CB  1 
ATOM   7601  O OG1 . THR C 1 311 ? 135.042 115.145 154.771 1.00 62.89  ? 257 THR C OG1 1 
ATOM   7602  C CG2 . THR C 1 311 ? 137.395 115.256 154.265 1.00 63.88  ? 257 THR C CG2 1 
ATOM   7603  N N   . VAL C 1 312 ? 133.296 116.336 152.491 1.00 70.08  ? 258 VAL C N   1 
ATOM   7604  C CA  . VAL C 1 312 ? 132.094 116.112 151.689 1.00 70.99  ? 258 VAL C CA  1 
ATOM   7605  C C   . VAL C 1 312 ? 131.956 117.166 150.598 1.00 76.09  ? 258 VAL C C   1 
ATOM   7606  O O   . VAL C 1 312 ? 131.653 116.840 149.442 1.00 77.36  ? 258 VAL C O   1 
ATOM   7607  C CB  . VAL C 1 312 ? 130.848 116.069 152.595 1.00 63.10  ? 258 VAL C CB  1 
ATOM   7608  C CG1 . VAL C 1 312 ? 129.584 116.086 151.757 1.00 65.09  ? 258 VAL C CG1 1 
ATOM   7609  C CG2 . VAL C 1 312 ? 130.879 114.828 153.470 1.00 60.01  ? 258 VAL C CG2 1 
ATOM   7610  N N   . LEU C 1 313 ? 132.180 118.439 150.932 1.00 70.44  ? 259 LEU C N   1 
ATOM   7611  C CA  . LEU C 1 313 ? 132.052 119.492 149.930 1.00 68.01  ? 259 LEU C CA  1 
ATOM   7612  C C   . LEU C 1 313 ? 133.132 119.385 148.859 1.00 75.19  ? 259 LEU C C   1 
ATOM   7613  O O   . LEU C 1 313 ? 132.867 119.648 147.680 1.00 84.10  ? 259 LEU C O   1 
ATOM   7614  C CB  . LEU C 1 313 ? 132.084 120.864 150.602 1.00 65.56  ? 259 LEU C CB  1 
ATOM   7615  C CG  . LEU C 1 313 ? 130.937 121.110 151.585 1.00 63.29  ? 259 LEU C CG  1 
ATOM   7616  C CD1 . LEU C 1 313 ? 130.891 122.561 152.029 1.00 65.47  ? 259 LEU C CD1 1 
ATOM   7617  C CD2 . LEU C 1 313 ? 129.607 120.688 150.982 1.00 68.11  ? 259 LEU C CD2 1 
ATOM   7618  N N   . THR C 1 314 ? 134.351 118.995 149.239 1.00 69.17  ? 260 THR C N   1 
ATOM   7619  C CA  . THR C 1 314 ? 135.390 118.775 148.241 1.00 71.61  ? 260 THR C CA  1 
ATOM   7620  C C   . THR C 1 314 ? 135.028 117.616 147.322 1.00 80.41  ? 260 THR C C   1 
ATOM   7621  O O   . THR C 1 314 ? 135.293 117.660 146.115 1.00 85.17  ? 260 THR C O   1 
ATOM   7622  C CB  . THR C 1 314 ? 136.730 118.520 148.926 1.00 67.36  ? 260 THR C CB  1 
ATOM   7623  O OG1 . THR C 1 314 ? 136.946 119.519 149.929 1.00 71.96  ? 260 THR C OG1 1 
ATOM   7624  C CG2 . THR C 1 314 ? 137.859 118.584 147.914 1.00 75.62  ? 260 THR C CG2 1 
ATOM   7625  N N   . MET C 1 315 ? 134.416 116.566 147.877 1.00 78.89  ? 261 MET C N   1 
ATOM   7626  C CA  . MET C 1 315 ? 133.929 115.475 147.040 1.00 78.77  ? 261 MET C CA  1 
ATOM   7627  C C   . MET C 1 315 ? 132.865 115.967 146.066 1.00 79.34  ? 261 MET C C   1 
ATOM   7628  O O   . MET C 1 315 ? 132.841 115.559 144.896 1.00 82.48  ? 261 MET C O   1 
ATOM   7629  C CB  . MET C 1 315 ? 133.381 114.351 147.918 1.00 70.99  ? 261 MET C CB  1 
ATOM   7630  C CG  . MET C 1 315 ? 133.153 113.044 147.183 1.00 75.83  ? 261 MET C CG  1 
ATOM   7631  S SD  . MET C 1 315 ? 134.699 112.247 146.717 1.00 86.70  ? 261 MET C SD  1 
ATOM   7632  C CE  . MET C 1 315 ? 135.422 111.974 148.330 1.00 70.91  ? 261 MET C CE  1 
ATOM   7633  N N   . THR C 1 316 ? 131.974 116.846 146.532 1.00 74.37  ? 262 THR C N   1 
ATOM   7634  C CA  . THR C 1 316 ? 130.977 117.424 145.635 1.00 76.21  ? 262 THR C CA  1 
ATOM   7635  C C   . THR C 1 316 ? 131.640 118.215 144.514 1.00 80.83  ? 262 THR C C   1 
ATOM   7636  O O   . THR C 1 316 ? 131.210 118.145 143.359 1.00 86.73  ? 262 THR C O   1 
ATOM   7637  C CB  . THR C 1 316 ? 130.009 118.325 146.403 1.00 72.46  ? 262 THR C CB  1 
ATOM   7638  O OG1 . THR C 1 316 ? 130.730 119.410 146.997 1.00 76.84  ? 262 THR C OG1 1 
ATOM   7639  C CG2 . THR C 1 316 ? 129.290 117.547 147.482 1.00 76.44  ? 262 THR C CG2 1 
ATOM   7640  N N   . THR C 1 317 ? 132.684 118.982 144.838 1.00 77.91  ? 263 THR C N   1 
ATOM   7641  C CA  . THR C 1 317 ? 133.393 119.734 143.804 1.00 79.70  ? 263 THR C CA  1 
ATOM   7642  C C   . THR C 1 317 ? 134.052 118.802 142.792 1.00 84.59  ? 263 THR C C   1 
ATOM   7643  O O   . THR C 1 317 ? 134.027 119.063 141.580 1.00 91.17  ? 263 THR C O   1 
ATOM   7644  C CB  . THR C 1 317 ? 134.442 120.651 144.433 1.00 74.84  ? 263 THR C CB  1 
ATOM   7645  O OG1 . THR C 1 317 ? 135.381 119.867 145.177 1.00 78.33  ? 263 THR C OG1 1 
ATOM   7646  C CG2 . THR C 1 317 ? 133.784 121.665 145.355 1.00 77.91  ? 263 THR C CG2 1 
ATOM   7647  N N   . ILE C 1 318 ? 134.661 117.717 143.274 1.00 83.92  ? 264 ILE C N   1 
ATOM   7648  C CA  . ILE C 1 318 ? 135.296 116.754 142.376 1.00 86.37  ? 264 ILE C CA  1 
ATOM   7649  C C   . ILE C 1 318 ? 134.261 116.136 141.447 1.00 87.93  ? 264 ILE C C   1 
ATOM   7650  O O   . ILE C 1 318 ? 134.512 115.943 140.251 1.00 88.87  ? 264 ILE C O   1 
ATOM   7651  C CB  . ILE C 1 318 ? 136.047 115.679 143.184 1.00 86.45  ? 264 ILE C CB  1 
ATOM   7652  C CG1 . ILE C 1 318 ? 137.182 116.309 143.993 1.00 86.37  ? 264 ILE C CG1 1 
ATOM   7653  C CG2 . ILE C 1 318 ? 136.598 114.607 142.262 1.00 81.26  ? 264 ILE C CG2 1 
ATOM   7654  C CD1 . ILE C 1 318 ? 137.857 115.345 144.946 1.00 76.90  ? 264 ILE C CD1 1 
ATOM   7655  N N   . ASN C 1 319 ? 133.082 115.812 141.982 1.00 90.01  ? 265 ASN C N   1 
ATOM   7656  C CA  . ASN C 1 319 ? 131.991 115.335 141.136 1.00 94.62  ? 265 ASN C CA  1 
ATOM   7657  C C   . ASN C 1 319 ? 131.578 116.392 140.118 1.00 99.30  ? 265 ASN C C   1 
ATOM   7658  O O   . ASN C 1 319 ? 131.341 116.081 138.945 1.00 96.23  ? 265 ASN C O   1 
ATOM   7659  C CB  . ASN C 1 319 ? 130.796 114.935 142.001 1.00 94.06  ? 265 ASN C CB  1 
ATOM   7660  C CG  . ASN C 1 319 ? 129.529 114.738 141.192 1.00 100.81 ? 265 ASN C CG  1 
ATOM   7661  O OD1 . ASN C 1 319 ? 129.549 114.136 140.118 1.00 102.18 ? 265 ASN C OD1 1 
ATOM   7662  N ND2 . ASN C 1 319 ? 128.417 115.256 141.701 1.00 102.65 ? 265 ASN C ND2 1 
ATOM   7663  N N   . THR C 1 320 ? 131.487 117.649 140.555 1.00 102.28 ? 266 THR C N   1 
ATOM   7664  C CA  . THR C 1 320 ? 131.010 118.725 139.692 1.00 102.52 ? 266 THR C CA  1 
ATOM   7665  C C   . THR C 1 320 ? 131.965 118.983 138.532 1.00 101.53 ? 266 THR C C   1 
ATOM   7666  O O   . THR C 1 320 ? 131.537 119.400 137.449 1.00 104.98 ? 266 THR C O   1 
ATOM   7667  C CB  . THR C 1 320 ? 130.815 119.994 140.527 1.00 97.83  ? 266 THR C CB  1 
ATOM   7668  O OG1 . THR C 1 320 ? 129.839 119.749 141.547 1.00 97.47  ? 266 THR C OG1 1 
ATOM   7669  C CG2 . THR C 1 320 ? 130.358 121.159 139.664 1.00 100.74 ? 266 THR C CG2 1 
ATOM   7670  N N   . HIS C 1 321 ? 133.261 118.739 138.743 1.00 97.85  ? 267 HIS C N   1 
ATOM   7671  C CA  . HIS C 1 321 ? 134.278 119.111 137.758 1.00 103.25 ? 267 HIS C CA  1 
ATOM   7672  C C   . HIS C 1 321 ? 133.948 118.610 136.352 1.00 108.97 ? 267 HIS C C   1 
ATOM   7673  O O   . HIS C 1 321 ? 133.773 119.403 135.421 1.00 109.70 ? 267 HIS C O   1 
ATOM   7674  C CB  . HIS C 1 321 ? 135.644 118.579 138.199 1.00 101.57 ? 267 HIS C CB  1 
ATOM   7675  C CG  . HIS C 1 321 ? 136.624 118.428 137.077 1.00 102.96 ? 267 HIS C CG  1 
ATOM   7676  N ND1 . HIS C 1 321 ? 136.914 119.449 136.197 1.00 103.45 ? 267 HIS C ND1 1 
ATOM   7677  C CD2 . HIS C 1 321 ? 137.377 117.372 136.689 1.00 97.47  ? 267 HIS C CD2 1 
ATOM   7678  C CE1 . HIS C 1 321 ? 137.804 119.028 135.316 1.00 98.79  ? 267 HIS C CE1 1 
ATOM   7679  N NE2 . HIS C 1 321 ? 138.102 117.772 135.593 1.00 95.27  ? 267 HIS C NE2 1 
ATOM   7680  N N   . LEU C 1 322 ? 133.857 117.291 136.179 1.00 106.41 ? 268 LEU C N   1 
ATOM   7681  C CA  . LEU C 1 322 ? 133.826 116.706 134.843 1.00 104.67 ? 268 LEU C CA  1 
ATOM   7682  C C   . LEU C 1 322 ? 132.467 116.789 134.159 1.00 104.56 ? 268 LEU C C   1 
ATOM   7683  O O   . LEU C 1 322 ? 132.368 116.424 132.983 1.00 101.04 ? 268 LEU C O   1 
ATOM   7684  C CB  . LEU C 1 322 ? 134.270 115.242 134.900 1.00 102.15 ? 268 LEU C CB  1 
ATOM   7685  C CG  . LEU C 1 322 ? 135.748 114.974 134.615 1.00 91.99  ? 268 LEU C CG  1 
ATOM   7686  C CD1 . LEU C 1 322 ? 136.075 113.505 134.826 1.00 81.78  ? 268 LEU C CD1 1 
ATOM   7687  C CD2 . LEU C 1 322 ? 136.101 115.403 133.199 1.00 86.99  ? 268 LEU C CD2 1 
ATOM   7688  N N   . ARG C 1 323 ? 131.422 117.250 134.849 1.00 103.78 ? 269 ARG C N   1 
ATOM   7689  C CA  . ARG C 1 323 ? 130.085 117.193 134.269 1.00 106.08 ? 269 ARG C CA  1 
ATOM   7690  C C   . ARG C 1 323 ? 129.897 118.161 133.106 1.00 111.01 ? 269 ARG C C   1 
ATOM   7691  O O   . ARG C 1 323 ? 128.901 118.046 132.383 1.00 111.91 ? 269 ARG C O   1 
ATOM   7692  C CB  . ARG C 1 323 ? 129.030 117.471 135.340 1.00 109.00 ? 269 ARG C CB  1 
ATOM   7693  C CG  . ARG C 1 323 ? 128.841 118.942 135.660 1.00 110.97 ? 269 ARG C CG  1 
ATOM   7694  C CD  . ARG C 1 323 ? 127.487 119.180 136.303 1.00 112.70 ? 269 ARG C CD  1 
ATOM   7695  N NE  . ARG C 1 323 ? 127.439 118.725 137.686 1.00 110.74 ? 269 ARG C NE  1 
ATOM   7696  C CZ  . ARG C 1 323 ? 127.362 119.533 138.734 1.00 109.18 ? 269 ARG C CZ  1 
ATOM   7697  N NH1 . ARG C 1 323 ? 127.288 120.845 138.589 1.00 106.51 ? 269 ARG C NH1 1 
ATOM   7698  N NH2 . ARG C 1 323 ? 127.353 119.011 139.957 1.00 107.83 ? 269 ARG C NH2 1 
ATOM   7699  N N   . GLU C 1 324 ? 130.816 119.105 132.905 1.00 112.22 ? 270 GLU C N   1 
ATOM   7700  C CA  . GLU C 1 324 ? 130.652 120.121 131.871 1.00 114.50 ? 270 GLU C CA  1 
ATOM   7701  C C   . GLU C 1 324 ? 131.254 119.734 130.527 1.00 104.32 ? 270 GLU C C   1 
ATOM   7702  O O   . GLU C 1 324 ? 131.062 120.466 129.550 1.00 94.29  ? 270 GLU C O   1 
ATOM   7703  C CB  . GLU C 1 324 ? 131.267 121.449 132.328 1.00 123.67 ? 270 GLU C CB  1 
ATOM   7704  C CG  . GLU C 1 324 ? 130.465 122.174 133.396 1.00 128.14 ? 270 GLU C CG  1 
ATOM   7705  C CD  . GLU C 1 324 ? 130.988 123.572 133.668 1.00 137.86 ? 270 GLU C CD  1 
ATOM   7706  O OE1 . GLU C 1 324 ? 132.138 123.867 133.279 1.00 139.48 ? 270 GLU C OE1 1 
ATOM   7707  O OE2 . GLU C 1 324 ? 130.246 124.378 134.267 1.00 142.76 ? 270 GLU C OE2 1 
ATOM   7708  N N   . THR C 1 325 ? 131.972 118.615 130.443 1.00 106.30 ? 271 THR C N   1 
ATOM   7709  C CA  . THR C 1 325 ? 132.640 118.217 129.210 1.00 103.02 ? 271 THR C CA  1 
ATOM   7710  C C   . THR C 1 325 ? 132.054 116.950 128.599 1.00 96.44  ? 271 THR C C   1 
ATOM   7711  O O   . THR C 1 325 ? 132.677 116.361 127.710 1.00 92.55  ? 271 THR C O   1 
ATOM   7712  C CB  . THR C 1 325 ? 134.139 118.032 129.458 1.00 105.10 ? 271 THR C CB  1 
ATOM   7713  O OG1 . THR C 1 325 ? 134.337 117.176 130.589 1.00 105.63 ? 271 THR C OG1 1 
ATOM   7714  C CG2 . THR C 1 325 ? 134.805 119.375 129.720 1.00 101.27 ? 271 THR C CG2 1 
ATOM   7715  N N   . LEU C 1 326 ? 130.883 116.520 129.043 1.00 94.19  ? 272 LEU C N   1 
ATOM   7716  C CA  . LEU C 1 326 ? 130.252 115.296 128.580 1.00 86.44  ? 272 LEU C CA  1 
ATOM   7717  C C   . LEU C 1 326 ? 128.786 115.550 128.271 1.00 85.12  ? 272 LEU C C   1 
ATOM   7718  O O   . LEU C 1 326 ? 128.177 116.473 128.823 1.00 90.45  ? 272 LEU C O   1 
ATOM   7719  C CB  . LEU C 1 326 ? 130.377 114.183 129.630 1.00 79.34  ? 272 LEU C CB  1 
ATOM   7720  C CG  . LEU C 1 326 ? 131.796 113.734 129.972 1.00 74.32  ? 272 LEU C CG  1 
ATOM   7721  C CD1 . LEU C 1 326 ? 131.761 112.646 131.023 1.00 72.67  ? 272 LEU C CD1 1 
ATOM   7722  C CD2 . LEU C 1 326 ? 132.517 113.250 128.728 1.00 71.77  ? 272 LEU C CD2 1 
ATOM   7723  N N   . PRO C 1 327 ? 128.190 114.750 127.390 1.00 79.66  ? 273 PRO C N   1 
ATOM   7724  C CA  . PRO C 1 327 ? 126.762 114.908 127.096 1.00 76.66  ? 273 PRO C CA  1 
ATOM   7725  C C   . PRO C 1 327 ? 125.901 114.422 128.252 1.00 75.87  ? 273 PRO C C   1 
ATOM   7726  O O   . PRO C 1 327 ? 126.383 113.899 129.258 1.00 76.03  ? 273 PRO C O   1 
ATOM   7727  C CB  . PRO C 1 327 ? 126.559 114.048 125.847 1.00 76.16  ? 273 PRO C CB  1 
ATOM   7728  C CG  . PRO C 1 327 ? 127.632 113.022 125.932 1.00 77.26  ? 273 PRO C CG  1 
ATOM   7729  C CD  . PRO C 1 327 ? 128.813 113.717 126.546 1.00 78.89  ? 273 PRO C CD  1 
ATOM   7730  N N   . LYS C 1 328 ? 124.591 114.602 128.086 1.00 72.42  ? 274 LYS C N   1 
ATOM   7731  C CA  . LYS C 1 328 ? 123.619 114.241 129.117 1.00 66.49  ? 274 LYS C CA  1 
ATOM   7732  C C   . LYS C 1 328 ? 123.148 112.796 128.932 1.00 66.24  ? 274 LYS C C   1 
ATOM   7733  O O   . LYS C 1 328 ? 121.965 112.505 128.757 1.00 66.34  ? 274 LYS C O   1 
ATOM   7734  C CB  . LYS C 1 328 ? 122.450 115.216 129.094 1.00 66.76  ? 274 LYS C CB  1 
ATOM   7735  C CG  . LYS C 1 328 ? 122.862 116.667 129.258 1.00 67.43  ? 274 LYS C CG  1 
ATOM   7736  C CD  . LYS C 1 328 ? 121.663 117.593 129.184 1.00 71.30  ? 274 LYS C CD  1 
ATOM   7737  C CE  . LYS C 1 328 ? 122.081 119.046 129.319 1.00 74.54  ? 274 LYS C CE  1 
ATOM   7738  N NZ  . LYS C 1 328 ? 120.916 119.962 129.189 1.00 74.46  ? 274 LYS C NZ  1 
ATOM   7739  N N   . ILE C 1 329 ? 124.114 111.883 128.973 1.00 64.49  ? 275 ILE C N   1 
ATOM   7740  C CA  . ILE C 1 329 ? 123.796 110.459 128.826 1.00 63.73  ? 275 ILE C CA  1 
ATOM   7741  C C   . ILE C 1 329 ? 123.019 109.983 130.048 1.00 65.94  ? 275 ILE C C   1 
ATOM   7742  O O   . ILE C 1 329 ? 123.334 110.393 131.182 1.00 68.46  ? 275 ILE C O   1 
ATOM   7743  C CB  . ILE C 1 329 ? 125.080 109.634 128.626 1.00 63.63  ? 275 ILE C CB  1 
ATOM   7744  C CG1 . ILE C 1 329 ? 126.293 110.356 129.217 1.00 62.37  ? 275 ILE C CG1 1 
ATOM   7745  C CG2 . ILE C 1 329 ? 125.297 109.350 127.150 1.00 67.30  ? 275 ILE C CG2 1 
ATOM   7746  C CD1 . ILE C 1 329 ? 126.450 110.188 130.709 1.00 65.05  ? 275 ILE C CD1 1 
ATOM   7747  N N   . PRO C 1 330 ? 122.002 109.132 129.886 1.00 67.78  ? 276 PRO C N   1 
ATOM   7748  C CA  . PRO C 1 330 ? 121.170 108.743 131.032 1.00 67.86  ? 276 PRO C CA  1 
ATOM   7749  C C   . PRO C 1 330 ? 121.795 107.702 131.945 1.00 68.42  ? 276 PRO C C   1 
ATOM   7750  O O   . PRO C 1 330 ? 121.415 107.636 133.121 1.00 71.44  ? 276 PRO C O   1 
ATOM   7751  C CB  . PRO C 1 330 ? 119.908 108.189 130.362 1.00 68.04  ? 276 PRO C CB  1 
ATOM   7752  C CG  . PRO C 1 330 ? 120.406 107.625 129.079 1.00 67.13  ? 276 PRO C CG  1 
ATOM   7753  C CD  . PRO C 1 330 ? 121.532 108.523 128.630 1.00 64.77  ? 276 PRO C CD  1 
ATOM   7754  N N   . TYR C 1 331 ? 122.727 106.891 131.457 1.00 67.87  ? 277 TYR C N   1 
ATOM   7755  C CA  . TYR C 1 331 ? 123.298 105.810 132.241 1.00 64.25  ? 277 TYR C CA  1 
ATOM   7756  C C   . TYR C 1 331 ? 124.381 106.345 133.178 1.00 60.84  ? 277 TYR C C   1 
ATOM   7757  O O   . TYR C 1 331 ? 124.562 107.556 133.333 1.00 61.07  ? 277 TYR C O   1 
ATOM   7758  C CB  . TYR C 1 331 ? 123.829 104.716 131.314 1.00 64.27  ? 277 TYR C CB  1 
ATOM   7759  C CG  . TYR C 1 331 ? 124.694 105.222 130.185 1.00 65.94  ? 277 TYR C CG  1 
ATOM   7760  C CD1 . TYR C 1 331 ? 126.025 105.545 130.396 1.00 65.47  ? 277 TYR C CD1 1 
ATOM   7761  C CD2 . TYR C 1 331 ? 124.182 105.360 128.903 1.00 64.43  ? 277 TYR C CD2 1 
ATOM   7762  C CE1 . TYR C 1 331 ? 126.818 106.001 129.367 1.00 65.12  ? 277 TYR C CE1 1 
ATOM   7763  C CE2 . TYR C 1 331 ? 124.969 105.813 127.866 1.00 67.28  ? 277 TYR C CE2 1 
ATOM   7764  C CZ  . TYR C 1 331 ? 126.287 106.133 128.104 1.00 68.47  ? 277 TYR C CZ  1 
ATOM   7765  O OH  . TYR C 1 331 ? 127.078 106.587 127.076 1.00 72.23  ? 277 TYR C OH  1 
ATOM   7766  N N   . VAL C 1 332 ? 125.115 105.432 133.809 1.00 59.56  ? 278 VAL C N   1 
ATOM   7767  C CA  . VAL C 1 332 ? 126.087 105.764 134.843 1.00 58.08  ? 278 VAL C CA  1 
ATOM   7768  C C   . VAL C 1 332 ? 127.479 105.421 134.335 1.00 57.11  ? 278 VAL C C   1 
ATOM   7769  O O   . VAL C 1 332 ? 127.721 104.295 133.889 1.00 59.72  ? 278 VAL C O   1 
ATOM   7770  C CB  . VAL C 1 332 ? 125.792 105.019 136.157 1.00 57.76  ? 278 VAL C CB  1 
ATOM   7771  C CG1 . VAL C 1 332 ? 126.781 105.429 137.231 1.00 65.36  ? 278 VAL C CG1 1 
ATOM   7772  C CG2 . VAL C 1 332 ? 124.371 105.280 136.608 1.00 57.89  ? 278 VAL C CG2 1 
ATOM   7773  N N   . LYS C 1 333 ? 128.385 106.387 134.408 0.50 55.13  ? 279 LYS C N   1 
ATOM   7774  C CA  . LYS C 1 333 ? 129.773 106.184 134.030 0.50 54.30  ? 279 LYS C CA  1 
ATOM   7775  C C   . LYS C 1 333 ? 130.555 105.564 135.185 0.50 56.03  ? 279 LYS C C   1 
ATOM   7776  O O   . LYS C 1 333 ? 130.070 105.456 136.313 0.50 60.19  ? 279 LYS C O   1 
ATOM   7777  C CB  . LYS C 1 333 ? 130.403 107.508 133.604 1.00 56.04  ? 279 LYS C CB  1 
ATOM   7778  C CG  . LYS C 1 333 ? 129.657 108.210 132.486 1.00 52.34  ? 279 LYS C CG  1 
ATOM   7779  C CD  . LYS C 1 333 ? 130.032 109.677 132.422 1.00 55.54  ? 279 LYS C CD  1 
ATOM   7780  C CE  . LYS C 1 333 ? 129.662 110.385 133.714 1.00 68.43  ? 279 LYS C CE  1 
ATOM   7781  N NZ  . LYS C 1 333 ? 130.006 111.831 133.675 1.00 74.46  ? 279 LYS C NZ  1 
ATOM   7782  N N   . ALA C 1 334 ? 131.786 105.144 134.889 1.00 54.29  ? 280 ALA C N   1 
ATOM   7783  C CA  . ALA C 1 334 ? 132.634 104.565 135.925 1.00 59.04  ? 280 ALA C CA  1 
ATOM   7784  C C   . ALA C 1 334 ? 133.065 105.616 136.941 1.00 63.49  ? 280 ALA C C   1 
ATOM   7785  O O   . ALA C 1 334 ? 133.112 105.339 138.147 1.00 67.19  ? 280 ALA C O   1 
ATOM   7786  C CB  . ALA C 1 334 ? 133.852 103.889 135.299 1.00 55.89  ? 280 ALA C CB  1 
ATOM   7787  N N   . ILE C 1 335 ? 133.392 106.826 136.476 1.00 57.35  ? 281 ILE C N   1 
ATOM   7788  C CA  . ILE C 1 335 ? 133.733 107.899 137.406 1.00 52.75  ? 281 ILE C CA  1 
ATOM   7789  C C   . ILE C 1 335 ? 132.547 108.214 138.301 1.00 60.76  ? 281 ILE C C   1 
ATOM   7790  O O   . ILE C 1 335 ? 132.712 108.525 139.485 1.00 69.88  ? 281 ILE C O   1 
ATOM   7791  C CB  . ILE C 1 335 ? 134.211 109.156 136.658 1.00 50.66  ? 281 ILE C CB  1 
ATOM   7792  C CG1 . ILE C 1 335 ? 133.405 109.369 135.377 1.00 57.97  ? 281 ILE C CG1 1 
ATOM   7793  C CG2 . ILE C 1 335 ? 135.707 109.096 136.402 1.00 52.90  ? 281 ILE C CG2 1 
ATOM   7794  C CD1 . ILE C 1 335 ? 133.499 110.779 134.841 1.00 63.05  ? 281 ILE C CD1 1 
ATOM   7795  N N   . ASP C 1 336 ? 131.333 108.152 137.751 1.00 59.46  ? 282 ASP C N   1 
ATOM   7796  C CA  . ASP C 1 336 ? 130.150 108.373 138.575 1.00 62.63  ? 282 ASP C CA  1 
ATOM   7797  C C   . ASP C 1 336 ? 130.053 107.332 139.680 1.00 63.93  ? 282 ASP C C   1 
ATOM   7798  O O   . ASP C 1 336 ? 129.772 107.671 140.834 1.00 66.52  ? 282 ASP C O   1 
ATOM   7799  C CB  . ASP C 1 336 ? 128.892 108.362 137.708 1.00 68.76  ? 282 ASP C CB  1 
ATOM   7800  C CG  . ASP C 1 336 ? 128.631 109.698 137.044 1.00 81.09  ? 282 ASP C CG  1 
ATOM   7801  O OD1 . ASP C 1 336 ? 129.372 110.663 137.329 1.00 82.34  ? 282 ASP C OD1 1 
ATOM   7802  O OD2 . ASP C 1 336 ? 127.681 109.785 136.238 1.00 89.25  ? 282 ASP C OD2 1 
ATOM   7803  N N   . MET C 1 337 ? 130.313 106.064 139.355 1.00 62.54  ? 283 MET C N   1 
ATOM   7804  C CA  . MET C 1 337 ? 130.280 105.012 140.367 1.00 65.24  ? 283 MET C CA  1 
ATOM   7805  C C   . MET C 1 337 ? 131.344 105.237 141.436 1.00 63.17  ? 283 MET C C   1 
ATOM   7806  O O   . MET C 1 337 ? 131.068 105.130 142.637 1.00 68.37  ? 283 MET C O   1 
ATOM   7807  C CB  . MET C 1 337 ? 130.468 103.645 139.708 1.00 68.21  ? 283 MET C CB  1 
ATOM   7808  C CG  . MET C 1 337 ? 129.288 103.181 138.876 1.00 73.57  ? 283 MET C CG  1 
ATOM   7809  S SD  . MET C 1 337 ? 127.826 102.886 139.885 1.00 104.63 ? 283 MET C SD  1 
ATOM   7810  C CE  . MET C 1 337 ? 128.471 101.694 141.053 1.00 85.94  ? 283 MET C CE  1 
ATOM   7811  N N   . TYR C 1 338 ? 132.572 105.546 141.017 1.00 59.37  ? 284 TYR C N   1 
ATOM   7812  C CA  . TYR C 1 338 ? 133.653 105.711 141.985 1.00 61.20  ? 284 TYR C CA  1 
ATOM   7813  C C   . TYR C 1 338 ? 133.419 106.922 142.881 1.00 66.01  ? 284 TYR C C   1 
ATOM   7814  O O   . TYR C 1 338 ? 133.645 106.856 144.097 1.00 71.24  ? 284 TYR C O   1 
ATOM   7815  C CB  . TYR C 1 338 ? 134.993 105.828 141.262 1.00 59.14  ? 284 TYR C CB  1 
ATOM   7816  C CG  . TYR C 1 338 ? 136.188 105.656 142.168 1.00 57.50  ? 284 TYR C CG  1 
ATOM   7817  C CD1 . TYR C 1 338 ? 136.573 104.397 142.604 1.00 59.99  ? 284 TYR C CD1 1 
ATOM   7818  C CD2 . TYR C 1 338 ? 136.936 106.748 142.581 1.00 53.83  ? 284 TYR C CD2 1 
ATOM   7819  C CE1 . TYR C 1 338 ? 137.664 104.230 143.429 1.00 56.96  ? 284 TYR C CE1 1 
ATOM   7820  C CE2 . TYR C 1 338 ? 138.031 106.590 143.406 1.00 57.08  ? 284 TYR C CE2 1 
ATOM   7821  C CZ  . TYR C 1 338 ? 138.389 105.329 143.827 1.00 58.23  ? 284 TYR C CZ  1 
ATOM   7822  O OH  . TYR C 1 338 ? 139.477 105.159 144.648 1.00 67.93  ? 284 TYR C OH  1 
ATOM   7823  N N   . LEU C 1 339 ? 132.967 108.036 142.302 1.00 64.11  ? 285 LEU C N   1 
ATOM   7824  C CA  . LEU C 1 339 ? 132.694 109.227 143.095 1.00 59.57  ? 285 LEU C CA  1 
ATOM   7825  C C   . LEU C 1 339 ? 131.500 109.016 144.011 1.00 62.35  ? 285 LEU C C   1 
ATOM   7826  O O   . LEU C 1 339 ? 131.486 109.517 145.138 1.00 67.19  ? 285 LEU C O   1 
ATOM   7827  C CB  . LEU C 1 339 ? 132.469 110.426 142.179 1.00 58.77  ? 285 LEU C CB  1 
ATOM   7828  C CG  . LEU C 1 339 ? 133.729 110.918 141.472 1.00 61.60  ? 285 LEU C CG  1 
ATOM   7829  C CD1 . LEU C 1 339 ? 133.394 112.007 140.471 1.00 72.67  ? 285 LEU C CD1 1 
ATOM   7830  C CD2 . LEU C 1 339 ? 134.725 111.417 142.499 1.00 63.63  ? 285 LEU C CD2 1 
ATOM   7831  N N   . MET C 1 340 ? 130.489 108.274 143.552 1.00 61.94  ? 286 MET C N   1 
ATOM   7832  C CA  . MET C 1 340 ? 129.383 107.916 144.430 1.00 62.50  ? 286 MET C CA  1 
ATOM   7833  C C   . MET C 1 340 ? 129.875 107.095 145.611 1.00 65.96  ? 286 MET C C   1 
ATOM   7834  O O   . MET C 1 340 ? 129.468 107.330 146.753 1.00 68.62  ? 286 MET C O   1 
ATOM   7835  C CB  . MET C 1 340 ? 128.323 107.147 143.644 1.00 70.13  ? 286 MET C CB  1 
ATOM   7836  C CG  . MET C 1 340 ? 127.195 106.598 144.493 1.00 81.91  ? 286 MET C CG  1 
ATOM   7837  S SD  . MET C 1 340 ? 126.147 105.437 143.596 1.00 107.40 ? 286 MET C SD  1 
ATOM   7838  C CE  . MET C 1 340 ? 125.592 106.460 142.235 1.00 86.30  ? 286 MET C CE  1 
ATOM   7839  N N   . GLY C 1 341 ? 130.768 106.137 145.358 1.00 63.17  ? 287 GLY C N   1 
ATOM   7840  C CA  . GLY C 1 341 ? 131.308 105.340 146.448 1.00 63.89  ? 287 GLY C CA  1 
ATOM   7841  C C   . GLY C 1 341 ? 132.091 106.172 147.444 1.00 62.68  ? 287 GLY C C   1 
ATOM   7842  O O   . GLY C 1 341 ? 131.914 106.044 148.658 1.00 66.70  ? 287 GLY C O   1 
ATOM   7843  N N   . CYS C 1 342 ? 132.967 107.045 146.943 1.00 54.90  ? 288 CYS C N   1 
ATOM   7844  C CA  . CYS C 1 342 ? 133.765 107.883 147.835 1.00 55.37  ? 288 CYS C CA  1 
ATOM   7845  C C   . CYS C 1 342 ? 132.887 108.853 148.619 1.00 60.09  ? 288 CYS C C   1 
ATOM   7846  O O   . CYS C 1 342 ? 133.130 109.107 149.809 1.00 68.75  ? 288 CYS C O   1 
ATOM   7847  C CB  . CYS C 1 342 ? 134.823 108.638 147.035 1.00 59.33  ? 288 CYS C CB  1 
ATOM   7848  S SG  . CYS C 1 342 ? 136.031 107.574 146.221 1.00 72.85  ? 288 CYS C SG  1 
ATOM   7849  N N   . PHE C 1 343 ? 131.867 109.413 147.968 1.00 56.15  ? 289 PHE C N   1 
ATOM   7850  C CA  . PHE C 1 343 ? 130.934 110.289 148.662 1.00 52.48  ? 289 PHE C CA  1 
ATOM   7851  C C   . PHE C 1 343 ? 130.187 109.533 149.747 1.00 56.51  ? 289 PHE C C   1 
ATOM   7852  O O   . PHE C 1 343 ? 129.971 110.059 150.844 1.00 64.26  ? 289 PHE C O   1 
ATOM   7853  C CB  . PHE C 1 343 ? 129.954 110.907 147.667 1.00 56.62  ? 289 PHE C CB  1 
ATOM   7854  C CG  . PHE C 1 343 ? 129.133 112.018 148.243 1.00 60.18  ? 289 PHE C CG  1 
ATOM   7855  C CD1 . PHE C 1 343 ? 129.581 113.323 148.185 1.00 66.62  ? 289 PHE C CD1 1 
ATOM   7856  C CD2 . PHE C 1 343 ? 127.917 111.758 148.851 1.00 59.94  ? 289 PHE C CD2 1 
ATOM   7857  C CE1 . PHE C 1 343 ? 128.834 114.348 148.718 1.00 69.03  ? 289 PHE C CE1 1 
ATOM   7858  C CE2 . PHE C 1 343 ? 127.166 112.780 149.388 1.00 64.33  ? 289 PHE C CE2 1 
ATOM   7859  C CZ  . PHE C 1 343 ? 127.624 114.078 149.319 1.00 67.63  ? 289 PHE C CZ  1 
ATOM   7860  N N   . VAL C 1 344 ? 129.786 108.293 149.462 1.00 59.42  ? 290 VAL C N   1 
ATOM   7861  C CA  . VAL C 1 344 ? 129.132 107.477 150.478 1.00 64.99  ? 290 VAL C CA  1 
ATOM   7862  C C   . VAL C 1 344 ? 130.077 107.231 151.645 1.00 64.20  ? 290 VAL C C   1 
ATOM   7863  O O   . VAL C 1 344 ? 129.670 107.282 152.808 1.00 67.11  ? 290 VAL C O   1 
ATOM   7864  C CB  . VAL C 1 344 ? 128.624 106.160 149.864 1.00 58.51  ? 290 VAL C CB  1 
ATOM   7865  C CG1 . VAL C 1 344 ? 128.271 105.166 150.954 1.00 51.76  ? 290 VAL C CG1 1 
ATOM   7866  C CG2 . VAL C 1 344 ? 127.414 106.428 148.989 1.00 60.05  ? 290 VAL C CG2 1 
ATOM   7867  N N   . PHE C 1 345 ? 131.355 106.978 151.358 1.00 58.65  ? 291 PHE C N   1 
ATOM   7868  C CA  . PHE C 1 345 ? 132.317 106.731 152.431 1.00 54.48  ? 291 PHE C CA  1 
ATOM   7869  C C   . PHE C 1 345 ? 132.463 107.949 153.338 1.00 60.67  ? 291 PHE C C   1 
ATOM   7870  O O   . PHE C 1 345 ? 132.394 107.834 154.569 1.00 61.15  ? 291 PHE C O   1 
ATOM   7871  C CB  . PHE C 1 345 ? 133.672 106.334 151.847 1.00 53.00  ? 291 PHE C CB  1 
ATOM   7872  C CG  . PHE C 1 345 ? 133.802 104.867 151.567 1.00 58.04  ? 291 PHE C CG  1 
ATOM   7873  C CD1 . PHE C 1 345 ? 133.902 103.959 152.606 1.00 61.62  ? 291 PHE C CD1 1 
ATOM   7874  C CD2 . PHE C 1 345 ? 133.834 104.396 150.268 1.00 60.65  ? 291 PHE C CD2 1 
ATOM   7875  C CE1 . PHE C 1 345 ? 134.022 102.610 152.353 1.00 62.56  ? 291 PHE C CE1 1 
ATOM   7876  C CE2 . PHE C 1 345 ? 133.954 103.048 150.009 1.00 60.15  ? 291 PHE C CE2 1 
ATOM   7877  C CZ  . PHE C 1 345 ? 134.048 102.153 151.053 1.00 60.52  ? 291 PHE C CZ  1 
ATOM   7878  N N   . VAL C 1 346 ? 132.660 109.130 152.749 1.00 60.96  ? 292 VAL C N   1 
ATOM   7879  C CA  . VAL C 1 346 ? 132.864 110.320 153.573 1.00 58.02  ? 292 VAL C CA  1 
ATOM   7880  C C   . VAL C 1 346 ? 131.579 110.695 154.312 1.00 58.18  ? 292 VAL C C   1 
ATOM   7881  O O   . VAL C 1 346 ? 131.614 111.120 155.477 1.00 67.23  ? 292 VAL C O   1 
ATOM   7882  C CB  . VAL C 1 346 ? 133.407 111.484 152.724 1.00 58.81  ? 292 VAL C CB  1 
ATOM   7883  C CG1 . VAL C 1 346 ? 134.791 111.147 152.197 1.00 57.66  ? 292 VAL C CG1 1 
ATOM   7884  C CG2 . VAL C 1 346 ? 132.473 111.806 151.579 1.00 64.03  ? 292 VAL C CG2 1 
ATOM   7885  N N   . PHE C 1 347 ? 130.426 110.531 153.658 1.00 53.06  ? 293 PHE C N   1 
ATOM   7886  C CA  . PHE C 1 347 ? 129.156 110.811 154.315 1.00 57.78  ? 293 PHE C CA  1 
ATOM   7887  C C   . PHE C 1 347 ? 128.921 109.858 155.477 1.00 65.76  ? 293 PHE C C   1 
ATOM   7888  O O   . PHE C 1 347 ? 128.402 110.263 156.523 1.00 72.62  ? 293 PHE C O   1 
ATOM   7889  C CB  . PHE C 1 347 ? 128.018 110.718 153.301 1.00 61.99  ? 293 PHE C CB  1 
ATOM   7890  C CG  . PHE C 1 347 ? 126.750 111.380 153.750 1.00 65.92  ? 293 PHE C CG  1 
ATOM   7891  C CD1 . PHE C 1 347 ? 125.847 110.708 154.556 1.00 63.91  ? 293 PHE C CD1 1 
ATOM   7892  C CD2 . PHE C 1 347 ? 126.455 112.672 153.354 1.00 69.66  ? 293 PHE C CD2 1 
ATOM   7893  C CE1 . PHE C 1 347 ? 124.680 111.317 154.964 1.00 69.80  ? 293 PHE C CE1 1 
ATOM   7894  C CE2 . PHE C 1 347 ? 125.289 113.285 153.758 1.00 73.59  ? 293 PHE C CE2 1 
ATOM   7895  C CZ  . PHE C 1 347 ? 124.401 112.607 154.564 1.00 78.00  ? 293 PHE C CZ  1 
ATOM   7896  N N   . LEU C 1 348 ? 129.288 108.586 155.310 1.00 61.78  ? 294 LEU C N   1 
ATOM   7897  C CA  . LEU C 1 348 ? 129.181 107.631 156.403 1.00 61.26  ? 294 LEU C CA  1 
ATOM   7898  C C   . LEU C 1 348 ? 130.127 107.975 157.539 1.00 65.45  ? 294 LEU C C   1 
ATOM   7899  O O   . LEU C 1 348 ? 129.781 107.774 158.702 1.00 67.13  ? 294 LEU C O   1 
ATOM   7900  C CB  . LEU C 1 348 ? 129.453 106.213 155.902 1.00 58.20  ? 294 LEU C CB  1 
ATOM   7901  C CG  . LEU C 1 348 ? 128.318 105.549 155.125 1.00 62.72  ? 294 LEU C CG  1 
ATOM   7902  C CD1 . LEU C 1 348 ? 128.661 104.104 154.809 1.00 68.07  ? 294 LEU C CD1 1 
ATOM   7903  C CD2 . LEU C 1 348 ? 127.018 105.639 155.905 1.00 60.15  ? 294 LEU C CD2 1 
ATOM   7904  N N   . ALA C 1 349 ? 131.318 108.488 157.230 1.00 65.46  ? 295 ALA C N   1 
ATOM   7905  C CA  . ALA C 1 349 ? 132.210 108.946 158.292 1.00 67.67  ? 295 ALA C CA  1 
ATOM   7906  C C   . ALA C 1 349 ? 131.566 110.070 159.098 1.00 68.73  ? 295 ALA C C   1 
ATOM   7907  O O   . ALA C 1 349 ? 131.564 110.050 160.338 1.00 72.96  ? 295 ALA C O   1 
ATOM   7908  C CB  . ALA C 1 349 ? 133.543 109.400 157.699 1.00 66.33  ? 295 ALA C CB  1 
ATOM   7909  N N   . LEU C 1 350 ? 130.998 111.058 158.402 1.00 66.16  ? 296 LEU C N   1 
ATOM   7910  C CA  . LEU C 1 350 ? 130.355 112.169 159.100 1.00 63.34  ? 296 LEU C CA  1 
ATOM   7911  C C   . LEU C 1 350 ? 129.153 111.698 159.915 1.00 70.77  ? 296 LEU C C   1 
ATOM   7912  O O   . LEU C 1 350 ? 128.960 112.128 161.059 1.00 78.75  ? 296 LEU C O   1 
ATOM   7913  C CB  . LEU C 1 350 ? 129.940 113.250 158.103 1.00 59.21  ? 296 LEU C CB  1 
ATOM   7914  C CG  . LEU C 1 350 ? 129.309 114.498 158.721 1.00 60.94  ? 296 LEU C CG  1 
ATOM   7915  C CD1 . LEU C 1 350 ? 130.214 115.068 159.796 1.00 69.18  ? 296 LEU C CD1 1 
ATOM   7916  C CD2 . LEU C 1 350 ? 129.027 115.541 157.658 1.00 60.49  ? 296 LEU C CD2 1 
ATOM   7917  N N   . LEU C 1 351 ? 128.339 110.806 159.348 1.00 69.54  ? 297 LEU C N   1 
ATOM   7918  C CA  . LEU C 1 351 ? 127.174 110.300 160.068 1.00 68.84  ? 297 LEU C CA  1 
ATOM   7919  C C   . LEU C 1 351 ? 127.585 109.437 161.254 1.00 76.07  ? 297 LEU C C   1 
ATOM   7920  O O   . LEU C 1 351 ? 126.905 109.424 162.287 1.00 83.99  ? 297 LEU C O   1 
ATOM   7921  C CB  . LEU C 1 351 ? 126.270 109.515 159.122 1.00 68.20  ? 297 LEU C CB  1 
ATOM   7922  C CG  . LEU C 1 351 ? 124.916 110.155 158.817 1.00 75.29  ? 297 LEU C CG  1 
ATOM   7923  C CD1 . LEU C 1 351 ? 124.078 109.237 157.945 1.00 83.60  ? 297 LEU C CD1 1 
ATOM   7924  C CD2 . LEU C 1 351 ? 124.188 110.484 160.109 1.00 80.17  ? 297 LEU C CD2 1 
ATOM   7925  N N   . GLU C 1 352 ? 128.688 108.699 161.122 1.00 72.91  ? 298 GLU C N   1 
ATOM   7926  C CA  . GLU C 1 352 ? 129.212 107.940 162.248 1.00 76.76  ? 298 GLU C CA  1 
ATOM   7927  C C   . GLU C 1 352 ? 129.627 108.870 163.373 1.00 77.46  ? 298 GLU C C   1 
ATOM   7928  O O   . GLU C 1 352 ? 129.350 108.597 164.548 1.00 79.80  ? 298 GLU C O   1 
ATOM   7929  C CB  . GLU C 1 352 ? 130.390 107.078 161.793 1.00 79.14  ? 298 GLU C CB  1 
ATOM   7930  C CG  . GLU C 1 352 ? 131.107 106.330 162.908 1.00 82.22  ? 298 GLU C CG  1 
ATOM   7931  C CD  . GLU C 1 352 ? 132.222 107.141 163.540 1.00 88.67  ? 298 GLU C CD  1 
ATOM   7932  O OE1 . GLU C 1 352 ? 132.613 108.173 162.957 1.00 83.97  ? 298 GLU C OE1 1 
ATOM   7933  O OE2 . GLU C 1 352 ? 132.703 106.748 164.623 1.00 98.96  ? 298 GLU C OE2 1 
ATOM   7934  N N   . TYR C 1 353 ? 130.286 109.982 163.038 1.00 77.44  ? 299 TYR C N   1 
ATOM   7935  C CA  . TYR C 1 353 ? 130.609 110.941 164.089 1.00 79.72  ? 299 TYR C CA  1 
ATOM   7936  C C   . TYR C 1 353 ? 129.346 111.521 164.709 1.00 75.71  ? 299 TYR C C   1 
ATOM   7937  O O   . TYR C 1 353 ? 129.299 111.770 165.917 1.00 80.61  ? 299 TYR C O   1 
ATOM   7938  C CB  . TYR C 1 353 ? 131.492 112.077 163.583 1.00 81.19  ? 299 TYR C CB  1 
ATOM   7939  C CG  . TYR C 1 353 ? 131.618 113.112 164.673 1.00 78.32  ? 299 TYR C CG  1 
ATOM   7940  C CD1 . TYR C 1 353 ? 132.301 112.817 165.842 1.00 80.03  ? 299 TYR C CD1 1 
ATOM   7941  C CD2 . TYR C 1 353 ? 130.996 114.347 164.571 1.00 73.91  ? 299 TYR C CD2 1 
ATOM   7942  C CE1 . TYR C 1 353 ? 132.397 113.730 166.859 1.00 80.74  ? 299 TYR C CE1 1 
ATOM   7943  C CE2 . TYR C 1 353 ? 131.089 115.270 165.589 1.00 76.28  ? 299 TYR C CE2 1 
ATOM   7944  C CZ  . TYR C 1 353 ? 131.792 114.954 166.729 1.00 78.36  ? 299 TYR C CZ  1 
ATOM   7945  O OH  . TYR C 1 353 ? 131.894 115.856 167.754 1.00 75.39  ? 299 TYR C OH  1 
ATOM   7946  N N   . ALA C 1 354 ? 128.324 111.777 163.893 1.00 74.28  ? 300 ALA C N   1 
ATOM   7947  C CA  . ALA C 1 354 ? 127.072 112.296 164.436 1.00 73.45  ? 300 ALA C CA  1 
ATOM   7948  C C   . ALA C 1 354 ? 126.451 111.314 165.422 1.00 76.09  ? 300 ALA C C   1 
ATOM   7949  O O   . ALA C 1 354 ? 125.974 111.711 166.492 1.00 83.12  ? 300 ALA C O   1 
ATOM   7950  C CB  . ALA C 1 354 ? 126.096 112.613 163.304 1.00 83.16  ? 300 ALA C CB  1 
ATOM   7951  N N   . PHE C 1 355 ? 126.458 110.025 165.083 1.00 76.52  ? 301 PHE C N   1 
ATOM   7952  C CA  . PHE C 1 355 ? 125.915 109.014 165.987 1.00 79.99  ? 301 PHE C CA  1 
ATOM   7953  C C   . PHE C 1 355 ? 126.740 108.920 167.267 1.00 83.51  ? 301 PHE C C   1 
ATOM   7954  O O   . PHE C 1 355 ? 126.185 108.769 168.366 1.00 88.03  ? 301 PHE C O   1 
ATOM   7955  C CB  . PHE C 1 355 ? 125.857 107.661 165.280 1.00 81.17  ? 301 PHE C CB  1 
ATOM   7956  C CG  . PHE C 1 355 ? 124.929 106.679 165.929 1.00 84.46  ? 301 PHE C CG  1 
ATOM   7957  C CD1 . PHE C 1 355 ? 123.590 106.637 165.577 1.00 84.87  ? 301 PHE C CD1 1 
ATOM   7958  C CD2 . PHE C 1 355 ? 125.394 105.797 166.888 1.00 84.51  ? 301 PHE C CD2 1 
ATOM   7959  C CE1 . PHE C 1 355 ? 122.732 105.733 166.171 1.00 86.14  ? 301 PHE C CE1 1 
ATOM   7960  C CE2 . PHE C 1 355 ? 124.542 104.891 167.485 1.00 89.42  ? 301 PHE C CE2 1 
ATOM   7961  C CZ  . PHE C 1 355 ? 123.209 104.859 167.126 1.00 89.38  ? 301 PHE C CZ  1 
ATOM   7962  N N   . VAL C 1 356 ? 128.066 109.003 167.141 1.00 82.16  ? 302 VAL C N   1 
ATOM   7963  C CA  . VAL C 1 356 ? 128.936 108.972 168.313 1.00 82.32  ? 302 VAL C CA  1 
ATOM   7964  C C   . VAL C 1 356 ? 128.653 110.163 169.219 1.00 86.58  ? 302 VAL C C   1 
ATOM   7965  O O   . VAL C 1 356 ? 128.600 110.030 170.447 1.00 88.24  ? 302 VAL C O   1 
ATOM   7966  C CB  . VAL C 1 356 ? 130.412 108.928 167.876 1.00 82.58  ? 302 VAL C CB  1 
ATOM   7967  C CG1 . VAL C 1 356 ? 131.326 109.171 169.060 1.00 92.86  ? 302 VAL C CG1 1 
ATOM   7968  C CG2 . VAL C 1 356 ? 130.727 107.593 167.233 1.00 84.45  ? 302 VAL C CG2 1 
ATOM   7969  N N   . ASN C 1 357 ? 128.472 111.346 168.629 1.00 87.79  ? 303 ASN C N   1 
ATOM   7970  C CA  . ASN C 1 357 ? 128.132 112.528 169.415 1.00 81.68  ? 303 ASN C CA  1 
ATOM   7971  C C   . ASN C 1 357 ? 126.785 112.358 170.100 1.00 80.03  ? 303 ASN C C   1 
ATOM   7972  O O   . ASN C 1 357 ? 126.613 112.753 171.259 1.00 87.72  ? 303 ASN C O   1 
ATOM   7973  C CB  . ASN C 1 357 ? 128.126 113.766 168.516 1.00 80.08  ? 303 ASN C CB  1 
ATOM   7974  C CG  . ASN C 1 357 ? 128.191 115.065 169.301 1.00 81.00  ? 303 ASN C CG  1 
ATOM   7975  O OD1 . ASN C 1 357 ? 127.614 115.189 170.381 1.00 81.47  ? 303 ASN C OD1 1 
ATOM   7976  N ND2 . ASN C 1 357 ? 128.902 116.045 168.756 1.00 82.90  ? 303 ASN C ND2 1 
ATOM   7977  N N   . TYR C 1 358 ? 125.815 111.774 169.397 1.00 78.62  ? 304 TYR C N   1 
ATOM   7978  C CA  . TYR C 1 358 ? 124.492 111.594 169.980 1.00 81.85  ? 304 TYR C CA  1 
ATOM   7979  C C   . TYR C 1 358 ? 124.526 110.649 171.175 1.00 89.79  ? 304 TYR C C   1 
ATOM   7980  O O   . TYR C 1 358 ? 123.889 110.917 172.200 1.00 94.55  ? 304 TYR C O   1 
ATOM   7981  C CB  . TYR C 1 358 ? 123.516 111.085 168.923 1.00 84.60  ? 304 TYR C CB  1 
ATOM   7982  C CG  . TYR C 1 358 ? 122.136 110.816 169.466 1.00 91.42  ? 304 TYR C CG  1 
ATOM   7983  C CD1 . TYR C 1 358 ? 121.289 111.861 169.804 1.00 95.77  ? 304 TYR C CD1 1 
ATOM   7984  C CD2 . TYR C 1 358 ? 121.680 109.519 169.642 1.00 93.95  ? 304 TYR C CD2 1 
ATOM   7985  C CE1 . TYR C 1 358 ? 120.027 111.621 170.302 1.00 100.23 ? 304 TYR C CE1 1 
ATOM   7986  C CE2 . TYR C 1 358 ? 120.418 109.270 170.138 1.00 99.14  ? 304 TYR C CE2 1 
ATOM   7987  C CZ  . TYR C 1 358 ? 119.596 110.324 170.466 1.00 103.97 ? 304 TYR C CZ  1 
ATOM   7988  O OH  . TYR C 1 358 ? 118.336 110.079 170.962 1.00 110.41 ? 304 TYR C OH  1 
ATOM   7989  N N   . ILE C 1 359 ? 125.263 109.542 171.070 1.00 91.73  ? 305 ILE C N   1 
ATOM   7990  C CA  . ILE C 1 359 ? 125.244 108.520 172.114 1.00 94.42  ? 305 ILE C CA  1 
ATOM   7991  C C   . ILE C 1 359 ? 126.424 108.646 173.075 1.00 98.36  ? 305 ILE C C   1 
ATOM   7992  O O   . ILE C 1 359 ? 126.613 107.778 173.931 1.00 103.17 ? 305 ILE C O   1 
ATOM   7993  C CB  . ILE C 1 359 ? 125.189 107.107 171.514 1.00 93.93  ? 305 ILE C CB  1 
ATOM   7994  C CG1 . ILE C 1 359 ? 126.542 106.725 170.915 1.00 98.54  ? 305 ILE C CG1 1 
ATOM   7995  C CG2 . ILE C 1 359 ? 124.094 107.018 170.465 1.00 92.40  ? 305 ILE C CG2 1 
ATOM   7996  C CD1 . ILE C 1 359 ? 126.653 105.263 170.562 1.00 99.26  ? 305 ILE C CD1 1 
ATOM   7997  N N   . PHE C 1 360 ? 127.225 109.706 172.955 1.00 99.09  ? 306 PHE C N   1 
ATOM   7998  C CA  . PHE C 1 360 ? 128.380 109.859 173.835 1.00 104.47 ? 306 PHE C CA  1 
ATOM   7999  C C   . PHE C 1 360 ? 127.963 110.139 175.274 1.00 110.41 ? 306 PHE C C   1 
ATOM   8000  O O   . PHE C 1 360 ? 128.543 109.578 176.211 1.00 113.16 ? 306 PHE C O   1 
ATOM   8001  C CB  . PHE C 1 360 ? 129.291 110.971 173.317 1.00 106.95 ? 306 PHE C CB  1 
ATOM   8002  C CG  . PHE C 1 360 ? 129.932 111.787 174.405 1.00 115.14 ? 306 PHE C CG  1 
ATOM   8003  C CD1 . PHE C 1 360 ? 130.995 111.282 175.139 1.00 114.10 ? 306 PHE C CD1 1 
ATOM   8004  C CD2 . PHE C 1 360 ? 129.476 113.064 174.688 1.00 116.14 ? 306 PHE C CD2 1 
ATOM   8005  C CE1 . PHE C 1 360 ? 131.580 112.032 176.141 1.00 116.94 ? 306 PHE C CE1 1 
ATOM   8006  C CE2 . PHE C 1 360 ? 130.062 113.819 175.686 1.00 117.27 ? 306 PHE C CE2 1 
ATOM   8007  C CZ  . PHE C 1 360 ? 131.115 113.303 176.412 1.00 117.67 ? 306 PHE C CZ  1 
ATOM   8008  N N   . PHE C 1 361 ? 126.970 111.009 175.471 1.00 109.37 ? 307 PHE C N   1 
ATOM   8009  C CA  . PHE C 1 361 ? 126.632 111.456 176.820 1.00 113.46 ? 307 PHE C CA  1 
ATOM   8010  C C   . PHE C 1 361 ? 126.141 110.303 177.686 1.00 111.90 ? 307 PHE C C   1 
ATOM   8011  O O   . PHE C 1 361 ? 126.478 110.221 178.873 1.00 112.27 ? 307 PHE C O   1 
ATOM   8012  C CB  . PHE C 1 361 ? 125.583 112.566 176.759 1.00 113.78 ? 307 PHE C CB  1 
ATOM   8013  C CG  . PHE C 1 361 ? 125.381 113.284 178.065 1.00 119.20 ? 307 PHE C CG  1 
ATOM   8014  C CD1 . PHE C 1 361 ? 126.179 114.364 178.406 1.00 122.08 ? 307 PHE C CD1 1 
ATOM   8015  C CD2 . PHE C 1 361 ? 124.392 112.884 178.948 1.00 118.20 ? 307 PHE C CD2 1 
ATOM   8016  C CE1 . PHE C 1 361 ? 125.996 115.029 179.605 1.00 121.67 ? 307 PHE C CE1 1 
ATOM   8017  C CE2 . PHE C 1 361 ? 124.205 113.545 180.148 1.00 118.01 ? 307 PHE C CE2 1 
ATOM   8018  C CZ  . PHE C 1 361 ? 125.008 114.618 180.476 1.00 121.19 ? 307 PHE C CZ  1 
ATOM   8019  N N   . SER C 1 362 ? 125.340 109.406 177.115 1.00 110.91 ? 308 SER C N   1 
ATOM   8020  C CA  . SER C 1 362 ? 124.782 108.299 177.881 1.00 108.87 ? 308 SER C CA  1 
ATOM   8021  C C   . SER C 1 362 ? 125.632 107.038 177.817 1.00 107.41 ? 308 SER C C   1 
ATOM   8022  O O   . SER C 1 362 ? 125.628 106.253 178.772 1.00 109.63 ? 308 SER C O   1 
ATOM   8023  C CB  . SER C 1 362 ? 123.365 107.987 177.391 1.00 106.51 ? 308 SER C CB  1 
ATOM   8024  O OG  . SER C 1 362 ? 123.342 107.788 175.989 1.00 109.35 ? 308 SER C OG  1 
ATOM   8025  N N   . GLN C 1 363 ? 126.361 106.821 176.722 1.00 104.81 ? 309 GLN C N   1 
ATOM   8026  C CA  . GLN C 1 363 ? 127.168 105.616 176.526 1.00 106.22 ? 309 GLN C CA  1 
ATOM   8027  C C   . GLN C 1 363 ? 128.547 106.008 176.010 1.00 109.74 ? 309 GLN C C   1 
ATOM   8028  O O   . GLN C 1 363 ? 128.833 105.892 174.811 1.00 112.87 ? 309 GLN C O   1 
ATOM   8029  C CB  . GLN C 1 363 ? 126.471 104.641 175.576 1.00 106.66 ? 309 GLN C CB  1 
ATOM   8030  C CG  . GLN C 1 363 ? 125.176 104.065 176.133 1.00 104.19 ? 309 GLN C CG  1 
ATOM   8031  C CD  . GLN C 1 363 ? 124.452 103.174 175.145 1.00 105.04 ? 309 GLN C CD  1 
ATOM   8032  O OE1 . GLN C 1 363 ? 124.326 103.506 173.967 1.00 108.42 ? 309 GLN C OE1 1 
ATOM   8033  N NE2 . GLN C 1 363 ? 123.971 102.032 175.622 1.00 99.76  ? 309 GLN C NE2 1 
ATOM   8034  N N   . PRO C 1 364 ? 129.431 106.482 176.895 1.00 107.07 ? 310 PRO C N   1 
ATOM   8035  C CA  . PRO C 1 364 ? 130.760 106.914 176.429 1.00 112.00 ? 310 PRO C CA  1 
ATOM   8036  C C   . PRO C 1 364 ? 131.647 105.772 175.962 1.00 112.31 ? 310 PRO C C   1 
ATOM   8037  O O   . PRO C 1 364 ? 132.321 105.899 174.930 1.00 113.58 ? 310 PRO C O   1 
ATOM   8038  C CB  . PRO C 1 364 ? 131.341 107.621 177.660 1.00 110.85 ? 310 PRO C CB  1 
ATOM   8039  C CG  . PRO C 1 364 ? 130.656 106.973 178.815 1.00 106.62 ? 310 PRO C CG  1 
ATOM   8040  C CD  . PRO C 1 364 ? 129.264 106.657 178.347 1.00 101.57 ? 310 PRO C CD  1 
ATOM   8041  N N   . ALA C 1 365 ? 131.678 104.659 176.702 1.00 109.02 ? 311 ALA C N   1 
ATOM   8042  C CA  . ALA C 1 365 ? 132.496 103.522 176.294 1.00 112.75 ? 311 ALA C CA  1 
ATOM   8043  C C   . ALA C 1 365 ? 132.035 102.954 174.960 1.00 113.74 ? 311 ALA C C   1 
ATOM   8044  O O   . ALA C 1 365 ? 132.864 102.545 174.139 1.00 110.25 ? 311 ALA C O   1 
ATOM   8045  C CB  . ALA C 1 365 ? 132.470 102.440 177.373 1.00 112.05 ? 311 ALA C CB  1 
ATOM   8046  N N   . ARG C 1 366 ? 130.722 102.924 174.726 1.00 111.87 ? 312 ARG C N   1 
ATOM   8047  C CA  . ARG C 1 366 ? 130.212 102.503 173.428 1.00 109.10 ? 312 ARG C CA  1 
ATOM   8048  C C   . ARG C 1 366 ? 130.697 103.431 172.321 1.00 104.75 ? 312 ARG C C   1 
ATOM   8049  O O   . ARG C 1 366 ? 131.053 102.973 171.230 1.00 104.82 ? 312 ARG C O   1 
ATOM   8050  C CB  . ARG C 1 366 ? 128.686 102.450 173.464 1.00 107.80 ? 312 ARG C CB  1 
ATOM   8051  C CG  . ARG C 1 366 ? 128.037 101.951 172.189 1.00 106.29 ? 312 ARG C CG  1 
ATOM   8052  C CD  . ARG C 1 366 ? 126.547 101.763 172.400 1.00 108.91 ? 312 ARG C CD  1 
ATOM   8053  N NE  . ARG C 1 366 ? 125.834 101.481 171.160 1.00 110.42 ? 312 ARG C NE  1 
ATOM   8054  C CZ  . ARG C 1 366 ? 124.525 101.285 171.084 1.00 109.75 ? 312 ARG C CZ  1 
ATOM   8055  N NH1 . ARG C 1 366 ? 123.757 101.325 172.160 1.00 111.39 ? 312 ARG C NH1 1 
ATOM   8056  N NH2 . ARG C 1 366 ? 123.973 101.043 169.899 1.00 107.90 ? 312 ARG C NH2 1 
ATOM   8057  N N   . ALA C 1 367 ? 130.721 104.740 172.583 1.00 102.48 ? 313 ALA C N   1 
ATOM   8058  C CA  . ALA C 1 367 ? 131.210 105.691 171.589 1.00 99.86  ? 313 ALA C CA  1 
ATOM   8059  C C   . ALA C 1 367 ? 132.686 105.459 171.282 1.00 100.31 ? 313 ALA C C   1 
ATOM   8060  O O   . ALA C 1 367 ? 133.108 105.504 170.119 1.00 100.50 ? 313 ALA C O   1 
ATOM   8061  C CB  . ALA C 1 367 ? 130.978 107.120 172.079 1.00 98.80  ? 313 ALA C CB  1 
ATOM   8062  N N   . ALA C 1 368 ? 133.489 105.217 172.321 1.00 101.85 ? 314 ALA C N   1 
ATOM   8063  C CA  . ALA C 1 368 ? 134.904 104.928 172.103 1.00 102.22 ? 314 ALA C CA  1 
ATOM   8064  C C   . ALA C 1 368 ? 135.082 103.644 171.302 1.00 102.90 ? 314 ALA C C   1 
ATOM   8065  O O   . ALA C 1 368 ? 135.942 103.567 170.414 1.00 100.96 ? 314 ALA C O   1 
ATOM   8066  C CB  . ALA C 1 368 ? 135.636 104.833 173.440 1.00 103.21 ? 314 ALA C CB  1 
ATOM   8067  N N   . ALA C 1 369 ? 134.274 102.625 171.604 1.00 101.54 ? 422 ALA C N   1 
ATOM   8068  C CA  . ALA C 1 369 ? 134.331 101.383 170.843 1.00 99.35  ? 422 ALA C CA  1 
ATOM   8069  C C   . ALA C 1 369 ? 133.967 101.617 169.384 1.00 96.84  ? 422 ALA C C   1 
ATOM   8070  O O   . ALA C 1 369 ? 134.589 101.047 168.482 1.00 94.89  ? 422 ALA C O   1 
ATOM   8071  C CB  . ALA C 1 369 ? 133.405 100.341 171.468 1.00 97.16  ? 422 ALA C CB  1 
ATOM   8072  N N   . ILE C 1 370 ? 132.956 102.450 169.133 1.00 94.59  ? 423 ILE C N   1 
ATOM   8073  C CA  . ILE C 1 370 ? 132.553 102.740 167.761 1.00 87.05  ? 423 ILE C CA  1 
ATOM   8074  C C   . ILE C 1 370 ? 133.677 103.441 167.014 1.00 86.35  ? 423 ILE C C   1 
ATOM   8075  O O   . ILE C 1 370 ? 133.964 103.121 165.855 1.00 91.68  ? 423 ILE C O   1 
ATOM   8076  C CB  . ILE C 1 370 ? 131.256 103.569 167.740 1.00 86.16  ? 423 ILE C CB  1 
ATOM   8077  C CG1 . ILE C 1 370 ? 130.081 102.733 168.243 1.00 89.88  ? 423 ILE C CG1 1 
ATOM   8078  C CG2 . ILE C 1 370 ? 130.972 104.074 166.339 1.00 89.23  ? 423 ILE C CG2 1 
ATOM   8079  C CD1 . ILE C 1 370 ? 128.761 103.463 168.207 1.00 89.95  ? 423 ILE C CD1 1 
ATOM   8080  N N   . ASP C 1 371 ? 134.331 104.408 167.660 1.00 87.42  ? 424 ASP C N   1 
ATOM   8081  C CA  . ASP C 1 371 ? 135.461 105.079 167.021 1.00 88.90  ? 424 ASP C CA  1 
ATOM   8082  C C   . ASP C 1 371 ? 136.574 104.089 166.692 1.00 88.56  ? 424 ASP C C   1 
ATOM   8083  O O   . ASP C 1 371 ? 137.107 104.077 165.572 1.00 91.63  ? 424 ASP C O   1 
ATOM   8084  C CB  . ASP C 1 371 ? 135.989 106.199 167.918 1.00 98.85  ? 424 ASP C CB  1 
ATOM   8085  C CG  . ASP C 1 371 ? 135.052 107.386 167.980 1.00 102.14 ? 424 ASP C CG  1 
ATOM   8086  O OD1 . ASP C 1 371 ? 133.967 107.320 167.365 1.00 99.89  ? 424 ASP C OD1 1 
ATOM   8087  O OD2 . ASP C 1 371 ? 135.400 108.386 168.640 1.00 101.53 ? 424 ASP C OD2 1 
ATOM   8088  N N   . ARG C 1 372 ? 136.929 103.236 167.658 1.00 91.49  ? 425 ARG C N   1 
ATOM   8089  C CA  . ARG C 1 372 ? 138.011 102.280 167.435 1.00 92.02  ? 425 ARG C CA  1 
ATOM   8090  C C   . ARG C 1 372 ? 137.669 101.308 166.313 1.00 86.45  ? 425 ARG C C   1 
ATOM   8091  O O   . ARG C 1 372 ? 138.523 100.987 165.478 1.00 84.08  ? 425 ARG C O   1 
ATOM   8092  C CB  . ARG C 1 372 ? 138.319 101.517 168.723 1.00 102.44 ? 425 ARG C CB  1 
ATOM   8093  C CG  . ARG C 1 372 ? 138.897 102.371 169.835 1.00 104.69 ? 425 ARG C CG  1 
ATOM   8094  C CD  . ARG C 1 372 ? 139.411 101.501 170.970 1.00 110.94 ? 425 ARG C CD  1 
ATOM   8095  N NE  . ARG C 1 372 ? 138.364 100.650 171.522 1.00 109.66 ? 425 ARG C NE  1 
ATOM   8096  C CZ  . ARG C 1 372 ? 137.676 100.926 172.622 1.00 110.97 ? 425 ARG C CZ  1 
ATOM   8097  N NH1 . ARG C 1 372 ? 137.909 102.022 173.326 1.00 110.33 ? 425 ARG C NH1 1 
ATOM   8098  N NH2 . ARG C 1 372 ? 136.732 100.081 173.026 1.00 114.79 ? 425 ARG C NH2 1 
ATOM   8099  N N   . TRP C 1 373 ? 136.426 100.826 166.279 1.00 87.79  ? 426 TRP C N   1 
ATOM   8100  C CA  . TRP C 1 373 ? 136.029 99.892  165.232 1.00 91.46  ? 426 TRP C CA  1 
ATOM   8101  C C   . TRP C 1 373 ? 135.974 100.573 163.872 1.00 87.33  ? 426 TRP C C   1 
ATOM   8102  O O   . TRP C 1 373 ? 136.300 99.954  162.854 1.00 84.52  ? 426 TRP C O   1 
ATOM   8103  C CB  . TRP C 1 373 ? 134.685 99.251  165.576 1.00 92.88  ? 426 TRP C CB  1 
ATOM   8104  C CG  . TRP C 1 373 ? 134.796 98.168  166.606 1.00 100.32 ? 426 TRP C CG  1 
ATOM   8105  C CD1 . TRP C 1 373 ? 134.223 98.149  167.843 1.00 101.43 ? 426 TRP C CD1 1 
ATOM   8106  C CD2 . TRP C 1 373 ? 135.539 96.949  166.490 1.00 104.09 ? 426 TRP C CD2 1 
ATOM   8107  N NE1 . TRP C 1 373 ? 134.557 96.991  168.503 1.00 103.08 ? 426 TRP C NE1 1 
ATOM   8108  C CE2 . TRP C 1 373 ? 135.365 96.237  167.693 1.00 105.77 ? 426 TRP C CE2 1 
ATOM   8109  C CE3 . TRP C 1 373 ? 136.331 96.388  165.483 1.00 98.37  ? 426 TRP C CE3 1 
ATOM   8110  C CZ2 . TRP C 1 373 ? 135.954 94.995  167.917 1.00 104.46 ? 426 TRP C CZ2 1 
ATOM   8111  C CZ3 . TRP C 1 373 ? 136.915 95.156  165.708 1.00 100.75 ? 426 TRP C CZ3 1 
ATOM   8112  C CH2 . TRP C 1 373 ? 136.724 94.473  166.914 1.00 103.03 ? 426 TRP C CH2 1 
ATOM   8113  N N   . SER C 1 374 ? 135.561 101.844 163.831 1.00 86.36  ? 427 SER C N   1 
ATOM   8114  C CA  . SER C 1 374 ? 135.570 102.584 162.575 1.00 80.75  ? 427 SER C CA  1 
ATOM   8115  C C   . SER C 1 374 ? 136.986 102.729 162.041 1.00 77.87  ? 427 SER C C   1 
ATOM   8116  O O   . SER C 1 374 ? 137.213 102.615 160.828 1.00 81.15  ? 427 SER C O   1 
ATOM   8117  C CB  . SER C 1 374 ? 134.929 103.958 162.765 1.00 81.07  ? 427 SER C CB  1 
ATOM   8118  O OG  . SER C 1 374 ? 133.570 103.840 163.142 1.00 84.50  ? 427 SER C OG  1 
ATOM   8119  N N   . ARG C 1 375 ? 137.953 102.944 162.943 1.00 74.40  ? 428 ARG C N   1 
ATOM   8120  C CA  . ARG C 1 375 ? 139.345 103.112 162.530 1.00 73.80  ? 428 ARG C CA  1 
ATOM   8121  C C   . ARG C 1 375 ? 139.836 101.946 161.685 1.00 81.40  ? 428 ARG C C   1 
ATOM   8122  O O   . ARG C 1 375 ? 140.727 102.119 160.846 1.00 84.10  ? 428 ARG C O   1 
ATOM   8123  C CB  . ARG C 1 375 ? 140.253 103.260 163.751 1.00 76.77  ? 428 ARG C CB  1 
ATOM   8124  C CG  . ARG C 1 375 ? 140.060 104.522 164.563 1.00 83.42  ? 428 ARG C CG  1 
ATOM   8125  C CD  . ARG C 1 375 ? 141.217 104.689 165.529 1.00 80.95  ? 428 ARG C CD  1 
ATOM   8126  N NE  . ARG C 1 375 ? 140.910 105.591 166.631 1.00 84.54  ? 428 ARG C NE  1 
ATOM   8127  C CZ  . ARG C 1 375 ? 141.735 105.838 167.639 1.00 92.35  ? 428 ARG C CZ  1 
ATOM   8128  N NH1 . ARG C 1 375 ? 142.928 105.272 167.709 1.00 93.60  ? 428 ARG C NH1 1 
ATOM   8129  N NH2 . ARG C 1 375 ? 141.352 106.671 168.603 1.00 93.36  ? 428 ARG C NH2 1 
ATOM   8130  N N   . ILE C 1 376 ? 139.288 100.755 161.899 1.00 83.81  ? 429 ILE C N   1 
ATOM   8131  C CA  . ILE C 1 376 ? 139.643 99.582  161.115 1.00 77.64  ? 429 ILE C CA  1 
ATOM   8132  C C   . ILE C 1 376 ? 138.671 99.359  159.963 1.00 74.29  ? 429 ILE C C   1 
ATOM   8133  O O   . ILE C 1 376 ? 139.092 99.063  158.845 1.00 73.69  ? 429 ILE C O   1 
ATOM   8134  C CB  . ILE C 1 376 ? 139.724 98.337  162.026 1.00 77.77  ? 429 ILE C CB  1 
ATOM   8135  C CG1 . ILE C 1 376 ? 141.012 98.363  162.852 1.00 78.38  ? 429 ILE C CG1 1 
ATOM   8136  C CG2 . ILE C 1 376 ? 139.631 97.060  161.208 1.00 77.97  ? 429 ILE C CG2 1 
ATOM   8137  C CD1 . ILE C 1 376 ? 141.243 97.108  163.671 1.00 85.42  ? 429 ILE C CD1 1 
ATOM   8138  N N   . VAL C 1 377 ? 137.369 99.510  160.218 1.00 74.77  ? 430 VAL C N   1 
ATOM   8139  C CA  . VAL C 1 377 ? 136.367 99.169  159.212 1.00 76.73  ? 430 VAL C CA  1 
ATOM   8140  C C   . VAL C 1 377 ? 136.492 100.067 157.989 1.00 75.81  ? 430 VAL C C   1 
ATOM   8141  O O   . VAL C 1 377 ? 136.455 99.587  156.849 1.00 74.23  ? 430 VAL C O   1 
ATOM   8142  C CB  . VAL C 1 377 ? 134.954 99.236  159.819 1.00 74.33  ? 430 VAL C CB  1 
ATOM   8143  C CG1 . VAL C 1 377 ? 133.906 99.195  158.720 1.00 72.31  ? 430 VAL C CG1 1 
ATOM   8144  C CG2 . VAL C 1 377 ? 134.744 98.086  160.784 1.00 76.52  ? 430 VAL C CG2 1 
ATOM   8145  N N   . PHE C 1 378 ? 136.638 101.378 158.194 1.00 73.00  ? 431 PHE C N   1 
ATOM   8146  C CA  . PHE C 1 378 ? 136.635 102.283 157.046 1.00 69.32  ? 431 PHE C CA  1 
ATOM   8147  C C   . PHE C 1 378 ? 137.789 102.029 156.084 1.00 70.57  ? 431 PHE C C   1 
ATOM   8148  O O   . PHE C 1 378 ? 137.530 101.891 154.875 1.00 72.53  ? 431 PHE C O   1 
ATOM   8149  C CB  . PHE C 1 378 ? 136.596 103.736 157.532 1.00 72.04  ? 431 PHE C CB  1 
ATOM   8150  C CG  . PHE C 1 378 ? 135.207 104.258 157.744 1.00 72.49  ? 431 PHE C CG  1 
ATOM   8151  C CD1 . PHE C 1 378 ? 134.550 104.050 158.943 1.00 70.90  ? 431 PHE C CD1 1 
ATOM   8152  C CD2 . PHE C 1 378 ? 134.551 104.943 156.736 1.00 69.60  ? 431 PHE C CD2 1 
ATOM   8153  C CE1 . PHE C 1 378 ? 133.269 104.525 159.137 1.00 71.35  ? 431 PHE C CE1 1 
ATOM   8154  C CE2 . PHE C 1 378 ? 133.271 105.420 156.923 1.00 68.71  ? 431 PHE C CE2 1 
ATOM   8155  C CZ  . PHE C 1 378 ? 132.629 105.211 158.125 1.00 69.93  ? 431 PHE C CZ  1 
ATOM   8156  N N   . PRO C 1 379 ? 139.054 101.949 156.518 1.00 70.62  ? 432 PRO C N   1 
ATOM   8157  C CA  . PRO C 1 379 ? 140.112 101.607 155.553 1.00 70.27  ? 432 PRO C CA  1 
ATOM   8158  C C   . PRO C 1 379 ? 139.922 100.244 154.913 1.00 71.63  ? 432 PRO C C   1 
ATOM   8159  O O   . PRO C 1 379 ? 140.174 100.088 153.712 1.00 73.47  ? 432 PRO C O   1 
ATOM   8160  C CB  . PRO C 1 379 ? 141.391 101.668 156.400 1.00 71.57  ? 432 PRO C CB  1 
ATOM   8161  C CG  . PRO C 1 379 ? 141.043 102.534 157.553 1.00 73.93  ? 432 PRO C CG  1 
ATOM   8162  C CD  . PRO C 1 379 ? 139.614 102.227 157.851 1.00 73.05  ? 432 PRO C CD  1 
ATOM   8163  N N   . PHE C 1 380 ? 139.459 99.254  155.679 1.00 71.65  ? 433 PHE C N   1 
ATOM   8164  C CA  . PHE C 1 380 ? 139.246 97.920  155.125 1.00 69.82  ? 433 PHE C CA  1 
ATOM   8165  C C   . PHE C 1 380 ? 138.146 97.936  154.071 1.00 70.44  ? 433 PHE C C   1 
ATOM   8166  O O   . PHE C 1 380 ? 138.291 97.355  152.988 1.00 73.64  ? 433 PHE C O   1 
ATOM   8167  C CB  . PHE C 1 380 ? 138.905 96.942  156.252 1.00 69.57  ? 433 PHE C CB  1 
ATOM   8168  C CG  . PHE C 1 380 ? 138.727 95.523  155.794 1.00 70.28  ? 433 PHE C CG  1 
ATOM   8169  C CD1 . PHE C 1 380 ? 139.809 94.663  155.730 1.00 70.49  ? 433 PHE C CD1 1 
ATOM   8170  C CD2 . PHE C 1 380 ? 137.476 95.045  155.440 1.00 72.06  ? 433 PHE C CD2 1 
ATOM   8171  C CE1 . PHE C 1 380 ? 139.649 93.356  155.314 1.00 73.59  ? 433 PHE C CE1 1 
ATOM   8172  C CE2 . PHE C 1 380 ? 137.310 93.740  155.023 1.00 72.36  ? 433 PHE C CE2 1 
ATOM   8173  C CZ  . PHE C 1 380 ? 138.398 92.894  154.960 1.00 74.86  ? 433 PHE C CZ  1 
ATOM   8174  N N   . THR C 1 381 ? 137.032 98.603  154.376 1.00 67.40  ? 434 THR C N   1 
ATOM   8175  C CA  . THR C 1 381 ? 135.929 98.678  153.426 1.00 68.49  ? 434 THR C CA  1 
ATOM   8176  C C   . THR C 1 381 ? 136.336 99.438  152.171 1.00 68.73  ? 434 THR C C   1 
ATOM   8177  O O   . THR C 1 381 ? 135.955 99.058  151.059 1.00 66.76  ? 434 THR C O   1 
ATOM   8178  C CB  . THR C 1 381 ? 134.717 99.335  154.080 1.00 71.03  ? 434 THR C CB  1 
ATOM   8179  O OG1 . THR C 1 381 ? 134.474 98.728  155.354 1.00 73.74  ? 434 THR C OG1 1 
ATOM   8180  C CG2 . THR C 1 381 ? 133.488 99.163  153.206 1.00 73.80  ? 434 THR C CG2 1 
ATOM   8181  N N   . PHE C 1 382 ? 137.111 100.513 152.326 1.00 69.12  ? 435 PHE C N   1 
ATOM   8182  C CA  . PHE C 1 382 ? 137.567 101.257 151.157 1.00 64.16  ? 435 PHE C CA  1 
ATOM   8183  C C   . PHE C 1 382 ? 138.529 100.430 150.316 1.00 67.61  ? 435 PHE C C   1 
ATOM   8184  O O   . PHE C 1 382 ? 138.503 100.503 149.083 1.00 70.44  ? 435 PHE C O   1 
ATOM   8185  C CB  . PHE C 1 382 ? 138.219 102.563 151.592 1.00 62.72  ? 435 PHE C CB  1 
ATOM   8186  C CG  . PHE C 1 382 ? 138.452 103.531 150.469 1.00 63.79  ? 435 PHE C CG  1 
ATOM   8187  C CD1 . PHE C 1 382 ? 137.385 104.133 149.826 1.00 60.52  ? 435 PHE C CD1 1 
ATOM   8188  C CD2 . PHE C 1 382 ? 139.738 103.856 150.070 1.00 64.24  ? 435 PHE C CD2 1 
ATOM   8189  C CE1 . PHE C 1 382 ? 137.595 105.028 148.797 1.00 57.04  ? 435 PHE C CE1 1 
ATOM   8190  C CE2 . PHE C 1 382 ? 139.952 104.752 149.044 1.00 61.21  ? 435 PHE C CE2 1 
ATOM   8191  C CZ  . PHE C 1 382 ? 138.879 105.338 148.407 1.00 55.33  ? 435 PHE C CZ  1 
ATOM   8192  N N   . SER C 1 383 ? 139.392 99.642  150.964 1.00 66.86  ? 436 SER C N   1 
ATOM   8193  C CA  . SER C 1 383 ? 140.277 98.749  150.224 1.00 64.95  ? 436 SER C CA  1 
ATOM   8194  C C   . SER C 1 383 ? 139.478 97.725  149.433 1.00 66.58  ? 436 SER C C   1 
ATOM   8195  O O   . SER C 1 383 ? 139.781 97.452  148.264 1.00 68.15  ? 436 SER C O   1 
ATOM   8196  C CB  . SER C 1 383 ? 141.235 98.048  151.186 1.00 64.33  ? 436 SER C CB  1 
ATOM   8197  O OG  . SER C 1 383 ? 141.869 98.979  152.044 1.00 71.06  ? 436 SER C OG  1 
ATOM   8198  N N   . LEU C 1 384 ? 138.448 97.148  150.056 1.00 64.46  ? 437 LEU C N   1 
ATOM   8199  C CA  . LEU C 1 384 ? 137.597 96.191  149.357 1.00 67.01  ? 437 LEU C CA  1 
ATOM   8200  C C   . LEU C 1 384 ? 136.882 96.848  148.183 1.00 68.18  ? 437 LEU C C   1 
ATOM   8201  O O   . LEU C 1 384 ? 136.761 96.254  147.102 1.00 70.19  ? 437 LEU C O   1 
ATOM   8202  C CB  . LEU C 1 384 ? 136.588 95.589  150.333 1.00 63.64  ? 437 LEU C CB  1 
ATOM   8203  C CG  . LEU C 1 384 ? 135.850 94.322  149.906 1.00 65.63  ? 437 LEU C CG  1 
ATOM   8204  C CD1 . LEU C 1 384 ? 136.802 93.139  149.887 1.00 61.40  ? 437 LEU C CD1 1 
ATOM   8205  C CD2 . LEU C 1 384 ? 134.673 94.056  150.830 1.00 69.35  ? 437 LEU C CD2 1 
ATOM   8206  N N   . PHE C 1 385 ? 136.392 98.074  148.383 1.00 67.17  ? 438 PHE C N   1 
ATOM   8207  C CA  . PHE C 1 385 ? 135.717 98.796  147.311 1.00 64.18  ? 438 PHE C CA  1 
ATOM   8208  C C   . PHE C 1 385 ? 136.662 99.072  146.152 1.00 64.10  ? 438 PHE C C   1 
ATOM   8209  O O   . PHE C 1 385 ? 136.286 98.917  144.986 1.00 67.10  ? 438 PHE C O   1 
ATOM   8210  C CB  . PHE C 1 385 ? 135.132 100.101 147.849 1.00 64.13  ? 438 PHE C CB  1 
ATOM   8211  C CG  . PHE C 1 385 ? 134.460 100.938 146.804 1.00 57.74  ? 438 PHE C CG  1 
ATOM   8212  C CD1 . PHE C 1 385 ? 133.200 100.606 146.342 1.00 58.28  ? 438 PHE C CD1 1 
ATOM   8213  C CD2 . PHE C 1 385 ? 135.084 102.059 146.288 1.00 60.28  ? 438 PHE C CD2 1 
ATOM   8214  C CE1 . PHE C 1 385 ? 132.576 101.374 145.382 1.00 66.27  ? 438 PHE C CE1 1 
ATOM   8215  C CE2 . PHE C 1 385 ? 134.465 102.831 145.327 1.00 61.87  ? 438 PHE C CE2 1 
ATOM   8216  C CZ  . PHE C 1 385 ? 133.209 102.488 144.874 1.00 62.24  ? 438 PHE C CZ  1 
ATOM   8217  N N   . ASN C 1 386 ? 137.897 99.479  146.452 1.00 63.60  ? 439 ASN C N   1 
ATOM   8218  C CA  . ASN C 1 386 ? 138.881 99.689  145.396 1.00 66.78  ? 439 ASN C CA  1 
ATOM   8219  C C   . ASN C 1 386 ? 139.171 98.394  144.654 1.00 70.07  ? 439 ASN C C   1 
ATOM   8220  O O   . ASN C 1 386 ? 139.253 98.381  143.420 1.00 73.07  ? 439 ASN C O   1 
ATOM   8221  C CB  . ASN C 1 386 ? 140.168 100.265 145.981 1.00 63.56  ? 439 ASN C CB  1 
ATOM   8222  C CG  . ASN C 1 386 ? 140.068 101.748 146.251 1.00 65.51  ? 439 ASN C CG  1 
ATOM   8223  O OD1 . ASN C 1 386 ? 140.597 102.563 145.497 1.00 68.77  ? 439 ASN C OD1 1 
ATOM   8224  N ND2 . ASN C 1 386 ? 139.381 102.107 147.328 1.00 65.53  ? 439 ASN C ND2 1 
ATOM   8225  N N   . LEU C 1 387 ? 139.322 97.291  145.389 1.00 66.62  ? 440 LEU C N   1 
ATOM   8226  C CA  . LEU C 1 387 ? 139.608 96.011  144.752 1.00 66.17  ? 440 LEU C CA  1 
ATOM   8227  C C   . LEU C 1 387 ? 138.493 95.613  143.795 1.00 66.49  ? 440 LEU C C   1 
ATOM   8228  O O   . LEU C 1 387 ? 138.748 95.274  142.634 1.00 70.24  ? 440 LEU C O   1 
ATOM   8229  C CB  . LEU C 1 387 ? 139.817 94.934  145.816 1.00 69.26  ? 440 LEU C CB  1 
ATOM   8230  C CG  . LEU C 1 387 ? 140.047 93.514  145.300 1.00 71.39  ? 440 LEU C CG  1 
ATOM   8231  C CD1 . LEU C 1 387 ? 141.232 93.480  144.352 1.00 72.14  ? 440 LEU C CD1 1 
ATOM   8232  C CD2 . LEU C 1 387 ? 140.262 92.559  146.460 1.00 75.15  ? 440 LEU C CD2 1 
ATOM   8233  N N   . VAL C 1 388 ? 137.242 95.676  144.254 1.00 61.18  ? 441 VAL C N   1 
ATOM   8234  C CA  . VAL C 1 388 ? 136.139 95.259  143.393 1.00 59.70  ? 441 VAL C CA  1 
ATOM   8235  C C   . VAL C 1 388 ? 135.977 96.223  142.220 1.00 66.04  ? 441 VAL C C   1 
ATOM   8236  O O   . VAL C 1 388 ? 135.732 95.798  141.083 1.00 70.64  ? 441 VAL C O   1 
ATOM   8237  C CB  . VAL C 1 388 ? 134.839 95.100  144.205 1.00 58.27  ? 441 VAL C CB  1 
ATOM   8238  C CG1 . VAL C 1 388 ? 134.421 96.407  144.850 1.00 62.65  ? 441 VAL C CG1 1 
ATOM   8239  C CG2 . VAL C 1 388 ? 133.726 94.557  143.323 1.00 61.43  ? 441 VAL C CG2 1 
ATOM   8240  N N   . TYR C 1 389 ? 136.134 97.529  142.463 1.00 64.06  ? 442 TYR C N   1 
ATOM   8241  C CA  . TYR C 1 389 ? 135.962 98.507  141.395 1.00 63.24  ? 442 TYR C CA  1 
ATOM   8242  C C   . TYR C 1 389 ? 137.008 98.328  140.304 1.00 64.57  ? 442 TYR C C   1 
ATOM   8243  O O   . TYR C 1 389 ? 136.682 98.368  139.112 1.00 69.44  ? 442 TYR C O   1 
ATOM   8244  C CB  . TYR C 1 389 ? 136.019 99.922  141.970 1.00 60.20  ? 442 TYR C CB  1 
ATOM   8245  C CG  . TYR C 1 389 ? 135.972 101.017 140.928 1.00 63.09  ? 442 TYR C CG  1 
ATOM   8246  C CD1 . TYR C 1 389 ? 134.768 101.419 140.368 1.00 61.52  ? 442 TYR C CD1 1 
ATOM   8247  C CD2 . TYR C 1 389 ? 137.132 101.656 140.514 1.00 61.66  ? 442 TYR C CD2 1 
ATOM   8248  C CE1 . TYR C 1 389 ? 134.723 102.421 139.420 1.00 58.34  ? 442 TYR C CE1 1 
ATOM   8249  C CE2 . TYR C 1 389 ? 137.095 102.658 139.566 1.00 58.34  ? 442 TYR C CE2 1 
ATOM   8250  C CZ  . TYR C 1 389 ? 135.889 103.036 139.023 1.00 56.24  ? 442 TYR C CZ  1 
ATOM   8251  O OH  . TYR C 1 389 ? 135.850 104.034 138.080 1.00 57.53  ? 442 TYR C OH  1 
ATOM   8252  N N   . TRP C 1 390 ? 138.266 98.121  140.684 1.00 61.48  ? 443 TRP C N   1 
ATOM   8253  C CA  . TRP C 1 390 ? 139.331 97.991  139.702 1.00 65.09  ? 443 TRP C CA  1 
ATOM   8254  C C   . TRP C 1 390 ? 139.493 96.568  139.185 1.00 70.38  ? 443 TRP C C   1 
ATOM   8255  O O   . TRP C 1 390 ? 140.303 96.346  138.280 1.00 73.93  ? 443 TRP C O   1 
ATOM   8256  C CB  . TRP C 1 390 ? 140.650 98.502  140.287 1.00 62.70  ? 443 TRP C CB  1 
ATOM   8257  C CG  . TRP C 1 390 ? 140.617 99.975  140.574 1.00 66.24  ? 443 TRP C CG  1 
ATOM   8258  C CD1 . TRP C 1 390 ? 140.338 100.570 141.768 1.00 65.30  ? 443 TRP C CD1 1 
ATOM   8259  C CD2 . TRP C 1 390 ? 140.851 101.039 139.643 1.00 68.28  ? 443 TRP C CD2 1 
ATOM   8260  N NE1 . TRP C 1 390 ? 140.392 101.936 141.643 1.00 64.76  ? 443 TRP C NE1 1 
ATOM   8261  C CE2 . TRP C 1 390 ? 140.705 102.250 140.347 1.00 63.29  ? 443 TRP C CE2 1 
ATOM   8262  C CE3 . TRP C 1 390 ? 141.175 101.084 138.284 1.00 71.83  ? 443 TRP C CE3 1 
ATOM   8263  C CZ2 . TRP C 1 390 ? 140.872 103.491 139.740 1.00 60.81  ? 443 TRP C CZ2 1 
ATOM   8264  C CZ3 . TRP C 1 390 ? 141.340 102.318 137.682 1.00 65.64  ? 443 TRP C CZ3 1 
ATOM   8265  C CH2 . TRP C 1 390 ? 141.188 103.504 138.410 1.00 61.48  ? 443 TRP C CH2 1 
ATOM   8266  N N   . LEU C 1 391 ? 138.758 95.601  139.736 1.00 68.46  ? 444 LEU C N   1 
ATOM   8267  C CA  . LEU C 1 391 ? 138.629 94.314  139.064 1.00 67.57  ? 444 LEU C CA  1 
ATOM   8268  C C   . LEU C 1 391 ? 137.500 94.318  138.042 1.00 69.61  ? 444 LEU C C   1 
ATOM   8269  O O   . LEU C 1 391 ? 137.621 93.692  136.984 1.00 71.99  ? 444 LEU C O   1 
ATOM   8270  C CB  . LEU C 1 391 ? 138.399 93.194  140.081 1.00 64.84  ? 444 LEU C CB  1 
ATOM   8271  C CG  . LEU C 1 391 ? 139.595 92.736  140.916 1.00 67.94  ? 444 LEU C CG  1 
ATOM   8272  C CD1 . LEU C 1 391 ? 139.273 91.428  141.621 1.00 65.37  ? 444 LEU C CD1 1 
ATOM   8273  C CD2 . LEU C 1 391 ? 140.843 92.599  140.057 1.00 66.90  ? 444 LEU C CD2 1 
ATOM   8274  N N   . TYR C 1 392 ? 136.398 95.010  138.343 1.00 67.65  ? 445 TYR C N   1 
ATOM   8275  C CA  . TYR C 1 392 ? 135.273 95.043  137.413 1.00 68.94  ? 445 TYR C CA  1 
ATOM   8276  C C   . TYR C 1 392 ? 135.611 95.831  136.152 1.00 68.99  ? 445 TYR C C   1 
ATOM   8277  O O   . TYR C 1 392 ? 135.310 95.386  135.038 1.00 63.73  ? 445 TYR C O   1 
ATOM   8278  C CB  . TYR C 1 392 ? 134.045 95.635  138.103 1.00 66.13  ? 445 TYR C CB  1 
ATOM   8279  C CG  . TYR C 1 392 ? 132.809 95.684  137.234 1.00 74.81  ? 445 TYR C CG  1 
ATOM   8280  C CD1 . TYR C 1 392 ? 131.941 94.603  137.168 1.00 79.60  ? 445 TYR C CD1 1 
ATOM   8281  C CD2 . TYR C 1 392 ? 132.505 96.814  136.487 1.00 73.48  ? 445 TYR C CD2 1 
ATOM   8282  C CE1 . TYR C 1 392 ? 130.809 94.644  136.378 1.00 84.12  ? 445 TYR C CE1 1 
ATOM   8283  C CE2 . TYR C 1 392 ? 131.376 96.864  135.694 1.00 76.36  ? 445 TYR C CE2 1 
ATOM   8284  C CZ  . TYR C 1 392 ? 130.532 95.778  135.644 1.00 89.36  ? 445 TYR C CZ  1 
ATOM   8285  O OH  . TYR C 1 392 ? 129.406 95.826  134.855 1.00 102.41 ? 445 TYR C OH  1 
ATOM   8286  N N   . TYR C 1 393 ? 136.240 96.995  136.301 1.00 69.50  ? 446 TYR C N   1 
ATOM   8287  C CA  . TYR C 1 393 ? 136.487 97.893  135.181 1.00 66.70  ? 446 TYR C CA  1 
ATOM   8288  C C   . TYR C 1 393 ? 137.856 97.709  134.543 1.00 70.14  ? 446 TYR C C   1 
ATOM   8289  O O   . TYR C 1 393 ? 138.184 98.440  133.603 1.00 75.69  ? 446 TYR C O   1 
ATOM   8290  C CB  . TYR C 1 393 ? 136.325 99.350  135.625 1.00 58.82  ? 446 TYR C CB  1 
ATOM   8291  C CG  . TYR C 1 393 ? 134.894 99.750  135.887 1.00 61.36  ? 446 TYR C CG  1 
ATOM   8292  C CD1 . TYR C 1 393 ? 134.062 100.142 134.850 1.00 60.13  ? 446 TYR C CD1 1 
ATOM   8293  C CD2 . TYR C 1 393 ? 134.376 99.736  137.172 1.00 67.97  ? 446 TYR C CD2 1 
ATOM   8294  C CE1 . TYR C 1 393 ? 132.754 100.507 135.086 1.00 59.08  ? 446 TYR C CE1 1 
ATOM   8295  C CE2 . TYR C 1 393 ? 133.068 100.101 137.417 1.00 68.16  ? 446 TYR C CE2 1 
ATOM   8296  C CZ  . TYR C 1 393 ? 132.262 100.485 136.371 1.00 62.17  ? 446 TYR C CZ  1 
ATOM   8297  O OH  . TYR C 1 393 ? 130.959 100.850 136.612 1.00 63.71  ? 446 TYR C OH  1 
ATOM   8298  N N   . VAL C 1 394 ? 138.661 96.767  135.021 1.00 70.26  ? 447 VAL C N   1 
ATOM   8299  C CA  . VAL C 1 394 ? 139.945 96.488  134.389 1.00 74.56  ? 447 VAL C CA  1 
ATOM   8300  C C   . VAL C 1 394 ? 140.115 94.988  134.186 1.00 75.42  ? 447 VAL C C   1 
ATOM   8301  O O   . VAL C 1 394 ? 140.112 94.218  135.146 1.00 79.47  ? 447 VAL C O   1 
ATOM   8302  C CB  . VAL C 1 394 ? 141.116 97.061  135.205 1.00 76.50  ? 447 VAL C CB  1 
ATOM   8303  C CG1 . VAL C 1 394 ? 142.439 96.584  134.629 1.00 76.55  ? 447 VAL C CG1 1 
ATOM   8304  C CG2 . VAL C 1 394 ? 141.063 98.580  135.221 1.00 67.20  ? 447 VAL C CG2 1 
ATOM   8305  N N   . ASN D 1 58  ? 123.943 100.313 69.222  1.00 135.96 ? 4   ASN D N   1 
ATOM   8306  C CA  . ASN D 1 58  ? 122.567 100.037 69.616  1.00 138.47 ? 4   ASN D CA  1 
ATOM   8307  C C   . ASN D 1 58  ? 122.536 99.226  70.908  1.00 143.88 ? 4   ASN D C   1 
ATOM   8308  O O   . ASN D 1 58  ? 121.513 99.162  71.591  1.00 141.89 ? 4   ASN D O   1 
ATOM   8309  C CB  . ASN D 1 58  ? 121.827 99.294  68.501  1.00 140.14 ? 4   ASN D CB  1 
ATOM   8310  C CG  . ASN D 1 58  ? 120.338 99.181  68.765  1.00 140.47 ? 4   ASN D CG  1 
ATOM   8311  O OD1 . ASN D 1 58  ? 119.560 100.054 68.380  1.00 138.21 ? 4   ASN D OD1 1 
ATOM   8312  N ND2 . ASN D 1 58  ? 119.934 98.102  69.425  1.00 142.49 ? 4   ASN D ND2 1 
ATOM   8313  N N   . ASP D 1 59  ? 123.668 98.608  71.233  1.00 147.12 ? 5   ASP D N   1 
ATOM   8314  C CA  . ASP D 1 59  ? 123.772 97.839  72.460  1.00 146.60 ? 5   ASP D CA  1 
ATOM   8315  C C   . ASP D 1 59  ? 123.715 98.763  73.675  1.00 144.73 ? 5   ASP D C   1 
ATOM   8316  O O   . ASP D 1 59  ? 124.062 99.944  73.584  1.00 138.80 ? 5   ASP D O   1 
ATOM   8317  C CB  . ASP D 1 59  ? 125.072 97.040  72.483  1.00 143.00 ? 5   ASP D CB  1 
ATOM   8318  C CG  . ASP D 1 59  ? 125.133 95.994  71.390  1.00 142.62 ? 5   ASP D CG  1 
ATOM   8319  O OD1 . ASP D 1 59  ? 124.134 95.839  70.657  1.00 146.11 ? 5   ASP D OD1 1 
ATOM   8320  O OD2 . ASP D 1 59  ? 126.181 95.327  71.265  1.00 138.76 ? 5   ASP D OD2 1 
ATOM   8321  N N   . PRO D 1 60  ? 123.268 98.251  74.824  1.00 145.36 ? 6   PRO D N   1 
ATOM   8322  C CA  . PRO D 1 60  ? 123.323 99.063  76.050  1.00 145.08 ? 6   PRO D CA  1 
ATOM   8323  C C   . PRO D 1 60  ? 124.730 99.501  76.412  1.00 146.64 ? 6   PRO D C   1 
ATOM   8324  O O   . PRO D 1 60  ? 124.899 100.541 77.060  1.00 148.14 ? 6   PRO D O   1 
ATOM   8325  C CB  . PRO D 1 60  ? 122.728 98.128  77.112  1.00 140.09 ? 6   PRO D CB  1 
ATOM   8326  C CG  . PRO D 1 60  ? 121.864 97.187  76.343  1.00 137.64 ? 6   PRO D CG  1 
ATOM   8327  C CD  . PRO D 1 60  ? 122.569 96.972  75.037  1.00 142.20 ? 6   PRO D CD  1 
ATOM   8328  N N   . GLY D 1 61  ? 125.747 98.737  76.014  1.00 145.34 ? 7   GLY D N   1 
ATOM   8329  C CA  . GLY D 1 61  ? 127.129 99.098  76.239  1.00 140.20 ? 7   GLY D CA  1 
ATOM   8330  C C   . GLY D 1 61  ? 127.712 100.087 75.258  1.00 137.84 ? 7   GLY D C   1 
ATOM   8331  O O   . GLY D 1 61  ? 128.865 100.496 75.418  1.00 135.73 ? 7   GLY D O   1 
ATOM   8332  N N   . ASN D 1 62  ? 126.951 100.486 74.241  1.00 136.95 ? 8   ASN D N   1 
ATOM   8333  C CA  . ASN D 1 62  ? 127.408 101.484 73.280  1.00 132.48 ? 8   ASN D CA  1 
ATOM   8334  C C   . ASN D 1 62  ? 127.172 102.867 73.874  1.00 130.48 ? 8   ASN D C   1 
ATOM   8335  O O   . ASN D 1 62  ? 126.027 103.313 73.992  1.00 129.56 ? 8   ASN D O   1 
ATOM   8336  C CB  . ASN D 1 62  ? 126.680 101.317 71.948  1.00 132.97 ? 8   ASN D CB  1 
ATOM   8337  C CG  . ASN D 1 62  ? 127.209 102.247 70.873  1.00 130.64 ? 8   ASN D CG  1 
ATOM   8338  O OD1 . ASN D 1 62  ? 128.252 102.878 71.041  1.00 130.85 ? 8   ASN D OD1 1 
ATOM   8339  N ND2 . ASN D 1 62  ? 126.493 102.334 69.759  1.00 133.55 ? 8   ASN D ND2 1 
ATOM   8340  N N   . MET D 1 63  ? 128.257 103.546 74.251  1.00 128.44 ? 9   MET D N   1 
ATOM   8341  C CA  . MET D 1 63  ? 128.123 104.817 74.955  1.00 122.48 ? 9   MET D CA  1 
ATOM   8342  C C   . MET D 1 63  ? 127.622 105.930 74.044  1.00 118.42 ? 9   MET D C   1 
ATOM   8343  O O   . MET D 1 63  ? 126.873 106.803 74.496  1.00 114.55 ? 9   MET D O   1 
ATOM   8344  C CB  . MET D 1 63  ? 129.456 105.209 75.591  1.00 123.45 ? 9   MET D CB  1 
ATOM   8345  C CG  . MET D 1 63  ? 129.954 104.222 76.633  1.00 125.76 ? 9   MET D CG  1 
ATOM   8346  S SD  . MET D 1 63  ? 131.364 104.852 77.561  1.00 130.47 ? 9   MET D SD  1 
ATOM   8347  C CE  . MET D 1 63  ? 130.643 106.310 78.309  1.00 115.58 ? 9   MET D CE  1 
ATOM   8348  N N   . SER D 1 64  ? 128.022 105.927 72.770  1.00 122.74 ? 10  SER D N   1 
ATOM   8349  C CA  . SER D 1 64  ? 127.600 106.995 71.870  1.00 122.13 ? 10  SER D CA  1 
ATOM   8350  C C   . SER D 1 64  ? 126.111 106.913 71.552  1.00 119.33 ? 10  SER D C   1 
ATOM   8351  O O   . SER D 1 64  ? 125.460 107.949 71.380  1.00 116.84 ? 10  SER D O   1 
ATOM   8352  C CB  . SER D 1 64  ? 128.427 106.961 70.586  1.00 122.39 ? 10  SER D CB  1 
ATOM   8353  O OG  . SER D 1 64  ? 128.385 105.681 69.986  1.00 128.47 ? 10  SER D OG  1 
ATOM   8354  N N   . PHE D 1 65  ? 125.556 105.702 71.475  1.00 118.54 ? 11  PHE D N   1 
ATOM   8355  C CA  . PHE D 1 65  ? 124.112 105.558 71.303  1.00 115.39 ? 11  PHE D CA  1 
ATOM   8356  C C   . PHE D 1 65  ? 123.354 106.135 72.494  1.00 110.36 ? 11  PHE D C   1 
ATOM   8357  O O   . PHE D 1 65  ? 122.350 106.841 72.326  1.00 108.77 ? 11  PHE D O   1 
ATOM   8358  C CB  . PHE D 1 65  ? 123.768 104.083 71.096  1.00 116.38 ? 11  PHE D CB  1 
ATOM   8359  C CG  . PHE D 1 65  ? 122.303 103.777 71.189  1.00 115.17 ? 11  PHE D CG  1 
ATOM   8360  C CD1 . PHE D 1 65  ? 121.457 104.031 70.123  1.00 116.43 ? 11  PHE D CD1 1 
ATOM   8361  C CD2 . PHE D 1 65  ? 121.775 103.214 72.337  1.00 113.44 ? 11  PHE D CD2 1 
ATOM   8362  C CE1 . PHE D 1 65  ? 120.110 103.741 70.208  1.00 113.33 ? 11  PHE D CE1 1 
ATOM   8363  C CE2 . PHE D 1 65  ? 120.430 102.923 72.427  1.00 113.19 ? 11  PHE D CE2 1 
ATOM   8364  C CZ  . PHE D 1 65  ? 119.597 103.186 71.361  1.00 112.12 ? 11  PHE D CZ  1 
ATOM   8365  N N   . VAL D 1 66  ? 123.828 105.854 73.709  1.00 109.37 ? 12  VAL D N   1 
ATOM   8366  C CA  . VAL D 1 66  ? 123.186 106.402 74.899  1.00 101.98 ? 12  VAL D CA  1 
ATOM   8367  C C   . VAL D 1 66  ? 123.342 107.917 74.938  1.00 101.98 ? 12  VAL D C   1 
ATOM   8368  O O   . VAL D 1 66  ? 122.437 108.636 75.376  1.00 102.96 ? 12  VAL D O   1 
ATOM   8369  C CB  . VAL D 1 66  ? 123.755 105.736 76.165  1.00 102.47 ? 12  VAL D CB  1 
ATOM   8370  C CG1 . VAL D 1 66  ? 123.053 106.262 77.405  1.00 102.56 ? 12  VAL D CG1 1 
ATOM   8371  C CG2 . VAL D 1 66  ? 123.614 104.226 76.073  1.00 105.96 ? 12  VAL D CG2 1 
ATOM   8372  N N   . LYS D 1 67  ? 124.490 108.427 74.485  1.00 101.47 ? 13  LYS D N   1 
ATOM   8373  C CA  . LYS D 1 67  ? 124.672 109.873 74.419  1.00 99.22  ? 13  LYS D CA  1 
ATOM   8374  C C   . LYS D 1 67  ? 123.703 110.503 73.429  1.00 99.11  ? 13  LYS D C   1 
ATOM   8375  O O   . LYS D 1 67  ? 123.157 111.581 73.684  1.00 96.55  ? 13  LYS D O   1 
ATOM   8376  C CB  . LYS D 1 67  ? 126.111 110.218 74.043  1.00 97.55  ? 13  LYS D CB  1 
ATOM   8377  C CG  . LYS D 1 67  ? 126.355 111.715 73.952  1.00 97.86  ? 13  LYS D CG  1 
ATOM   8378  C CD  . LYS D 1 67  ? 127.753 112.040 73.468  1.00 101.86 ? 13  LYS D CD  1 
ATOM   8379  C CE  . LYS D 1 67  ? 127.946 113.544 73.355  1.00 103.10 ? 13  LYS D CE  1 
ATOM   8380  N NZ  . LYS D 1 67  ? 129.317 113.896 72.897  1.00 104.52 ? 13  LYS D NZ  1 
ATOM   8381  N N   . GLU D 1 68  ? 123.487 109.847 72.287  1.00 103.73 ? 14  GLU D N   1 
ATOM   8382  C CA  . GLU D 1 68  ? 122.493 110.330 71.335  1.00 102.92 ? 14  GLU D CA  1 
ATOM   8383  C C   . GLU D 1 68  ? 121.108 110.356 71.963  1.00 101.16 ? 14  GLU D C   1 
ATOM   8384  O O   . GLU D 1 68  ? 120.360 111.326 71.799  1.00 103.08 ? 14  GLU D O   1 
ATOM   8385  C CB  . GLU D 1 68  ? 122.487 109.453 70.084  1.00 108.13 ? 14  GLU D CB  1 
ATOM   8386  C CG  . GLU D 1 68  ? 123.690 109.629 69.179  1.00 117.46 ? 14  GLU D CG  1 
ATOM   8387  C CD  . GLU D 1 68  ? 123.577 108.805 67.912  1.00 129.98 ? 14  GLU D CD  1 
ATOM   8388  O OE1 . GLU D 1 68  ? 122.702 107.914 67.860  1.00 129.48 ? 14  GLU D OE1 1 
ATOM   8389  O OE2 . GLU D 1 68  ? 124.356 109.050 66.968  1.00 137.84 ? 14  GLU D OE2 1 
ATOM   8390  N N   . THR D 1 69  ? 120.755 109.297 72.694  1.00 99.96  ? 15  THR D N   1 
ATOM   8391  C CA  . THR D 1 69  ? 119.451 109.257 73.350  1.00 95.13  ? 15  THR D CA  1 
ATOM   8392  C C   . THR D 1 69  ? 119.306 110.386 74.366  1.00 91.81  ? 15  THR D C   1 
ATOM   8393  O O   . THR D 1 69  ? 118.268 111.055 74.421  1.00 91.33  ? 15  THR D O   1 
ATOM   8394  C CB  . THR D 1 69  ? 119.245 107.903 74.027  1.00 96.47  ? 15  THR D CB  1 
ATOM   8395  O OG1 . THR D 1 69  ? 119.638 106.857 73.131  1.00 103.60 ? 15  THR D OG1 1 
ATOM   8396  C CG2 . THR D 1 69  ? 117.786 107.716 74.396  1.00 91.33  ? 15  THR D CG2 1 
ATOM   8397  N N   . VAL D 1 70  ? 120.345 110.624 75.169  1.00 92.42  ? 16  VAL D N   1 
ATOM   8398  C CA  . VAL D 1 70  ? 120.274 111.663 76.193  1.00 91.42  ? 16  VAL D CA  1 
ATOM   8399  C C   . VAL D 1 70  ? 120.196 113.047 75.556  1.00 91.48  ? 16  VAL D C   1 
ATOM   8400  O O   . VAL D 1 70  ? 119.431 113.910 76.007  1.00 90.48  ? 16  VAL D O   1 
ATOM   8401  C CB  . VAL D 1 70  ? 121.467 111.546 77.158  1.00 89.09  ? 16  VAL D CB  1 
ATOM   8402  C CG1 . VAL D 1 70  ? 121.490 112.720 78.122  1.00 83.59  ? 16  VAL D CG1 1 
ATOM   8403  C CG2 . VAL D 1 70  ? 121.392 110.237 77.926  1.00 87.29  ? 16  VAL D CG2 1 
ATOM   8404  N N   . ASP D 1 71  ? 120.988 113.288 74.508  1.00 91.80  ? 17  ASP D N   1 
ATOM   8405  C CA  . ASP D 1 71  ? 120.937 114.579 73.832  1.00 91.95  ? 17  ASP D CA  1 
ATOM   8406  C C   . ASP D 1 71  ? 119.592 114.801 73.156  1.00 90.11  ? 17  ASP D C   1 
ATOM   8407  O O   . ASP D 1 71  ? 119.114 115.939 73.089  1.00 89.26  ? 17  ASP D O   1 
ATOM   8408  C CB  . ASP D 1 71  ? 122.073 114.691 72.816  1.00 99.20  ? 17  ASP D CB  1 
ATOM   8409  C CG  . ASP D 1 71  ? 123.439 114.734 73.472  1.00 103.13 ? 17  ASP D CG  1 
ATOM   8410  O OD1 . ASP D 1 71  ? 123.543 114.346 74.655  1.00 102.72 ? 17  ASP D OD1 1 
ATOM   8411  O OD2 . ASP D 1 71  ? 124.406 115.165 72.811  1.00 105.47 ? 17  ASP D OD2 1 
ATOM   8412  N N   . LYS D 1 72  ? 118.970 113.736 72.648  1.00 90.08  ? 18  LYS D N   1 
ATOM   8413  C CA  . LYS D 1 72  ? 117.602 113.852 72.158  1.00 87.89  ? 18  LYS D CA  1 
ATOM   8414  C C   . LYS D 1 72  ? 116.646 114.198 73.291  1.00 88.33  ? 18  LYS D C   1 
ATOM   8415  O O   . LYS D 1 72  ? 115.726 115.005 73.115  1.00 89.49  ? 18  LYS D O   1 
ATOM   8416  C CB  . LYS D 1 72  ? 117.178 112.551 71.477  1.00 85.55  ? 18  LYS D CB  1 
ATOM   8417  C CG  . LYS D 1 72  ? 115.707 112.494 71.112  1.00 85.61  ? 18  LYS D CG  1 
ATOM   8418  C CD  . LYS D 1 72  ? 115.323 111.116 70.608  1.00 81.62  ? 18  LYS D CD  1 
ATOM   8419  C CE  . LYS D 1 72  ? 113.831 111.021 70.345  1.00 70.70  ? 18  LYS D CE  1 
ATOM   8420  N NZ  . LYS D 1 72  ? 113.444 109.663 69.876  1.00 70.39  ? 18  LYS D NZ  1 
ATOM   8421  N N   . LEU D 1 73  ? 116.851 113.593 74.463  1.00 87.05  ? 19  LEU D N   1 
ATOM   8422  C CA  . LEU D 1 73  ? 115.995 113.878 75.611  1.00 81.59  ? 19  LEU D CA  1 
ATOM   8423  C C   . LEU D 1 73  ? 116.077 115.345 76.011  1.00 83.04  ? 19  LEU D C   1 
ATOM   8424  O O   . LEU D 1 73  ? 115.053 115.989 76.267  1.00 83.78  ? 19  LEU D O   1 
ATOM   8425  C CB  . LEU D 1 73  ? 116.381 112.984 76.790  1.00 78.30  ? 19  LEU D CB  1 
ATOM   8426  C CG  . LEU D 1 73  ? 115.984 111.511 76.727  1.00 76.01  ? 19  LEU D CG  1 
ATOM   8427  C CD1 . LEU D 1 73  ? 116.449 110.781 77.977  1.00 74.12  ? 19  LEU D CD1 1 
ATOM   8428  C CD2 . LEU D 1 73  ? 114.483 111.379 76.556  1.00 76.70  ? 19  LEU D CD2 1 
ATOM   8429  N N   . LEU D 1 74  ? 117.288 115.892 76.070  1.00 83.62  ? 20  LEU D N   1 
ATOM   8430  C CA  . LEU D 1 74  ? 117.495 117.251 76.552  1.00 80.57  ? 20  LEU D CA  1 
ATOM   8431  C C   . LEU D 1 74  ? 117.475 118.294 75.440  1.00 86.54  ? 20  LEU D C   1 
ATOM   8432  O O   . LEU D 1 74  ? 117.768 119.465 75.702  1.00 82.93  ? 20  LEU D O   1 
ATOM   8433  C CB  . LEU D 1 74  ? 118.808 117.343 77.333  1.00 72.87  ? 20  LEU D CB  1 
ATOM   8434  C CG  . LEU D 1 74  ? 118.854 116.539 78.635  1.00 71.62  ? 20  LEU D CG  1 
ATOM   8435  C CD1 . LEU D 1 74  ? 119.954 117.055 79.543  1.00 70.27  ? 20  LEU D CD1 1 
ATOM   8436  C CD2 . LEU D 1 74  ? 117.514 116.577 79.348  1.00 72.83  ? 20  LEU D CD2 1 
ATOM   8437  N N   . LYS D 1 75  ? 117.143 117.900 74.213  1.00 93.11  ? 21  LYS D N   1 
ATOM   8438  C CA  . LYS D 1 75  ? 116.962 118.845 73.120  1.00 92.73  ? 21  LYS D CA  1 
ATOM   8439  C C   . LYS D 1 75  ? 115.513 119.309 73.090  1.00 93.31  ? 21  LYS D C   1 
ATOM   8440  O O   . LYS D 1 75  ? 114.592 118.488 73.128  1.00 96.55  ? 21  LYS D O   1 
ATOM   8441  C CB  . LYS D 1 75  ? 117.342 118.210 71.783  1.00 91.40  ? 21  LYS D CB  1 
ATOM   8442  C CG  . LYS D 1 75  ? 116.943 119.031 70.569  1.00 91.37  ? 21  LYS D CG  1 
ATOM   8443  C CD  . LYS D 1 75  ? 117.282 118.305 69.278  1.00 99.68  ? 21  LYS D CD  1 
ATOM   8444  C CE  . LYS D 1 75  ? 116.745 119.052 68.068  1.00 103.86 ? 21  LYS D CE  1 
ATOM   8445  N NZ  . LYS D 1 75  ? 117.068 118.353 66.795  1.00 109.54 ? 21  LYS D NZ  1 
ATOM   8446  N N   . GLY D 1 76  ? 115.314 120.623 73.021  1.00 92.64  ? 22  GLY D N   1 
ATOM   8447  C CA  . GLY D 1 76  ? 113.971 121.159 73.088  1.00 88.70  ? 22  GLY D CA  1 
ATOM   8448  C C   . GLY D 1 76  ? 113.346 121.073 74.459  1.00 86.44  ? 22  GLY D C   1 
ATOM   8449  O O   . GLY D 1 76  ? 112.119 121.104 74.576  1.00 84.00  ? 22  GLY D O   1 
ATOM   8450  N N   . TYR D 1 77  ? 114.161 120.966 75.503  1.00 84.38  ? 23  TYR D N   1 
ATOM   8451  C CA  . TYR D 1 77  ? 113.689 120.805 76.871  1.00 78.41  ? 23  TYR D CA  1 
ATOM   8452  C C   . TYR D 1 77  ? 113.776 122.151 77.577  1.00 75.20  ? 23  TYR D C   1 
ATOM   8453  O O   . TYR D 1 77  ? 114.856 122.747 77.654  1.00 76.78  ? 23  TYR D O   1 
ATOM   8454  C CB  . TYR D 1 77  ? 114.520 119.750 77.601  1.00 76.84  ? 23  TYR D CB  1 
ATOM   8455  C CG  . TYR D 1 77  ? 114.015 119.392 78.979  1.00 70.26  ? 23  TYR D CG  1 
ATOM   8456  C CD1 . TYR D 1 77  ? 114.458 120.077 80.101  1.00 65.67  ? 23  TYR D CD1 1 
ATOM   8457  C CD2 . TYR D 1 77  ? 113.107 118.359 79.159  1.00 66.93  ? 23  TYR D CD2 1 
ATOM   8458  C CE1 . TYR D 1 77  ? 114.004 119.749 81.360  1.00 65.36  ? 23  TYR D CE1 1 
ATOM   8459  C CE2 . TYR D 1 77  ? 112.648 118.025 80.415  1.00 65.59  ? 23  TYR D CE2 1 
ATOM   8460  C CZ  . TYR D 1 77  ? 113.100 118.724 81.512  1.00 67.86  ? 23  TYR D CZ  1 
ATOM   8461  O OH  . TYR D 1 77  ? 112.646 118.396 82.767  1.00 69.76  ? 23  TYR D OH  1 
ATOM   8462  N N   . ASP D 1 78  ? 112.645 122.626 78.090  1.00 70.24  ? 24  ASP D N   1 
ATOM   8463  C CA  . ASP D 1 78  ? 112.564 123.919 78.762  1.00 70.98  ? 24  ASP D CA  1 
ATOM   8464  C C   . ASP D 1 78  ? 112.468 123.673 80.262  1.00 68.33  ? 24  ASP D C   1 
ATOM   8465  O O   . ASP D 1 78  ? 111.441 123.194 80.754  1.00 66.60  ? 24  ASP D O   1 
ATOM   8466  C CB  . ASP D 1 78  ? 111.369 124.723 78.254  1.00 69.93  ? 24  ASP D CB  1 
ATOM   8467  C CG  . ASP D 1 78  ? 111.583 126.220 78.368  1.00 74.83  ? 24  ASP D CG  1 
ATOM   8468  O OD1 . ASP D 1 78  ? 112.711 126.638 78.701  1.00 72.28  ? 24  ASP D OD1 1 
ATOM   8469  O OD2 . ASP D 1 78  ? 110.624 126.979 78.121  1.00 80.93  ? 24  ASP D OD2 1 
ATOM   8470  N N   . ILE D 1 79  ? 113.541 124.001 80.986  1.00 67.01  ? 25  ILE D N   1 
ATOM   8471  C CA  . ILE D 1 79  ? 113.555 123.837 82.435  1.00 63.48  ? 25  ILE D CA  1 
ATOM   8472  C C   . ILE D 1 79  ? 112.644 124.820 83.147  1.00 66.47  ? 25  ILE D C   1 
ATOM   8473  O O   . ILE D 1 79  ? 112.412 124.674 84.352  1.00 69.16  ? 25  ILE D O   1 
ATOM   8474  C CB  . ILE D 1 79  ? 114.989 123.980 82.983  1.00 62.88  ? 25  ILE D CB  1 
ATOM   8475  C CG1 . ILE D 1 79  ? 115.541 125.372 82.672  1.00 60.89  ? 25  ILE D CG1 1 
ATOM   8476  C CG2 . ILE D 1 79  ? 115.886 122.909 82.397  1.00 63.80  ? 25  ILE D CG2 1 
ATOM   8477  C CD1 . ILE D 1 79  ? 116.969 125.581 83.127  1.00 61.32  ? 25  ILE D CD1 1 
ATOM   8478  N N   . ARG D 1 80  ? 112.123 125.816 82.437  1.00 64.76  ? 26  ARG D N   1 
ATOM   8479  C CA  . ARG D 1 80  ? 111.241 126.814 83.021  1.00 62.89  ? 26  ARG D CA  1 
ATOM   8480  C C   . ARG D 1 80  ? 109.787 126.367 83.077  1.00 61.12  ? 26  ARG D C   1 
ATOM   8481  O O   . ARG D 1 80  ? 108.957 127.086 83.642  1.00 65.40  ? 26  ARG D O   1 
ATOM   8482  C CB  . ARG D 1 80  ? 111.343 128.121 82.230  1.00 64.00  ? 26  ARG D CB  1 
ATOM   8483  C CG  . ARG D 1 80  ? 112.755 128.670 82.141  1.00 66.58  ? 26  ARG D CG  1 
ATOM   8484  C CD  . ARG D 1 80  ? 112.861 129.779 81.110  1.00 71.80  ? 26  ARG D CD  1 
ATOM   8485  N NE  . ARG D 1 80  ? 112.599 129.294 79.761  1.00 73.24  ? 26  ARG D NE  1 
ATOM   8486  C CZ  . ARG D 1 80  ? 112.822 129.995 78.658  1.00 73.25  ? 26  ARG D CZ  1 
ATOM   8487  N NH1 . ARG D 1 80  ? 113.327 131.217 78.706  1.00 73.89  ? 26  ARG D NH1 1 
ATOM   8488  N NH2 . ARG D 1 80  ? 112.532 129.456 77.477  1.00 72.39  ? 26  ARG D NH2 1 
ATOM   8489  N N   . LEU D 1 81  ? 109.460 125.209 82.510  1.00 58.54  ? 27  LEU D N   1 
ATOM   8490  C CA  . LEU D 1 81  ? 108.092 124.715 82.448  1.00 56.02  ? 27  LEU D CA  1 
ATOM   8491  C C   . LEU D 1 81  ? 107.985 123.406 83.211  1.00 59.86  ? 27  LEU D C   1 
ATOM   8492  O O   . LEU D 1 81  ? 108.817 122.511 83.037  1.00 61.36  ? 27  LEU D O   1 
ATOM   8493  C CB  . LEU D 1 81  ? 107.648 124.510 81.000  1.00 59.61  ? 27  LEU D CB  1 
ATOM   8494  C CG  . LEU D 1 81  ? 107.637 125.744 80.102  1.00 61.20  ? 27  LEU D CG  1 
ATOM   8495  C CD1 . LEU D 1 81  ? 107.316 125.347 78.674  1.00 54.93  ? 27  LEU D CD1 1 
ATOM   8496  C CD2 . LEU D 1 81  ? 106.633 126.759 80.616  1.00 61.36  ? 27  LEU D CD2 1 
ATOM   8497  N N   . ARG D 1 82  ? 106.961 123.297 84.052  1.00 60.82  ? 28  ARG D N   1 
ATOM   8498  C CA  . ARG D 1 82  ? 106.691 122.054 84.744  1.00 54.27  ? 28  ARG D CA  1 
ATOM   8499  C C   . ARG D 1 82  ? 106.133 121.021 83.769  1.00 59.43  ? 28  ARG D C   1 
ATOM   8500  O O   . ARG D 1 82  ? 105.603 121.372 82.713  1.00 64.89  ? 28  ARG D O   1 
ATOM   8501  C CB  . ARG D 1 82  ? 105.701 122.284 85.881  1.00 50.34  ? 28  ARG D CB  1 
ATOM   8502  C CG  . ARG D 1 82  ? 104.285 122.553 85.412  1.00 54.15  ? 28  ARG D CG  1 
ATOM   8503  C CD  . ARG D 1 82  ? 103.303 122.432 86.555  1.00 57.82  ? 28  ARG D CD  1 
ATOM   8504  N NE  . ARG D 1 82  ? 101.921 122.548 86.105  1.00 61.58  ? 28  ARG D NE  1 
ATOM   8505  C CZ  . ARG D 1 82  ? 101.194 121.535 85.654  1.00 61.80  ? 28  ARG D CZ  1 
ATOM   8506  N NH1 . ARG D 1 82  ? 101.695 120.315 85.556  1.00 59.72  ? 28  ARG D NH1 1 
ATOM   8507  N NH2 . ARG D 1 82  ? 99.933  121.753 85.293  1.00 61.60  ? 28  ARG D NH2 1 
ATOM   8508  N N   . PRO D 1 83  ? 106.252 119.735 84.096  1.00 56.10  ? 29  PRO D N   1 
ATOM   8509  C CA  . PRO D 1 83  ? 105.614 118.707 83.268  1.00 59.37  ? 29  PRO D CA  1 
ATOM   8510  C C   . PRO D 1 83  ? 104.105 118.892 83.240  1.00 64.85  ? 29  PRO D C   1 
ATOM   8511  O O   . PRO D 1 83  ? 103.496 119.318 84.224  1.00 66.44  ? 29  PRO D O   1 
ATOM   8512  C CB  . PRO D 1 83  ? 106.008 117.398 83.959  1.00 57.44  ? 29  PRO D CB  1 
ATOM   8513  C CG  . PRO D 1 83  ? 107.236 117.730 84.731  1.00 57.56  ? 29  PRO D CG  1 
ATOM   8514  C CD  . PRO D 1 83  ? 107.063 119.147 85.175  1.00 55.09  ? 29  PRO D CD  1 
ATOM   8515  N N   . ASP D 1 84  ? 103.504 118.560 82.096  1.00 62.85  ? 30  ASP D N   1 
ATOM   8516  C CA  . ASP D 1 84  ? 102.070 118.722 81.870  1.00 65.39  ? 30  ASP D CA  1 
ATOM   8517  C C   . ASP D 1 84  ? 101.621 120.163 82.078  1.00 66.91  ? 30  ASP D C   1 
ATOM   8518  O O   . ASP D 1 84  ? 100.547 120.409 82.631  1.00 71.31  ? 30  ASP D O   1 
ATOM   8519  C CB  . ASP D 1 84  ? 101.254 117.783 82.763  1.00 67.81  ? 30  ASP D CB  1 
ATOM   8520  C CG  . ASP D 1 84  ? 101.888 116.419 82.901  1.00 81.18  ? 30  ASP D CG  1 
ATOM   8521  O OD1 . ASP D 1 84  ? 102.949 116.195 82.280  1.00 86.82  ? 30  ASP D OD1 1 
ATOM   8522  O OD2 . ASP D 1 84  ? 101.333 115.573 83.632  1.00 81.54  ? 30  ASP D OD2 1 
ATOM   8523  N N   . PHE D 1 85  ? 102.441 121.121 81.648  1.00 64.99  ? 31  PHE D N   1 
ATOM   8524  C CA  . PHE D 1 85  ? 102.112 122.529 81.820  1.00 63.35  ? 31  PHE D CA  1 
ATOM   8525  C C   . PHE D 1 85  ? 100.793 122.857 81.136  1.00 66.09  ? 31  PHE D C   1 
ATOM   8526  O O   . PHE D 1 85  ? 100.592 122.544 79.960  1.00 70.99  ? 31  PHE D O   1 
ATOM   8527  C CB  . PHE D 1 85  ? 103.235 123.399 81.256  1.00 58.81  ? 31  PHE D CB  1 
ATOM   8528  C CG  . PHE D 1 85  ? 103.127 124.843 81.638  1.00 61.23  ? 31  PHE D CG  1 
ATOM   8529  C CD1 . PHE D 1 85  ? 103.758 125.318 82.775  1.00 64.63  ? 31  PHE D CD1 1 
ATOM   8530  C CD2 . PHE D 1 85  ? 102.395 125.726 80.865  1.00 63.13  ? 31  PHE D CD2 1 
ATOM   8531  C CE1 . PHE D 1 85  ? 103.661 126.646 83.132  1.00 69.37  ? 31  PHE D CE1 1 
ATOM   8532  C CE2 . PHE D 1 85  ? 102.294 127.055 81.217  1.00 65.81  ? 31  PHE D CE2 1 
ATOM   8533  C CZ  . PHE D 1 85  ? 102.927 127.517 82.351  1.00 67.95  ? 31  PHE D CZ  1 
ATOM   8534  N N   . GLY D 1 86  ? 99.894  123.494 81.883  1.00 65.26  ? 32  GLY D N   1 
ATOM   8535  C CA  . GLY D 1 86  ? 98.560  123.778 81.415  1.00 65.34  ? 32  GLY D CA  1 
ATOM   8536  C C   . GLY D 1 86  ? 97.586  122.626 81.548  1.00 67.25  ? 32  GLY D C   1 
ATOM   8537  O O   . GLY D 1 86  ? 96.382  122.825 81.354  1.00 69.23  ? 32  GLY D O   1 
ATOM   8538  N N   . GLY D 1 87  ? 98.072  121.430 81.871  1.00 65.77  ? 33  GLY D N   1 
ATOM   8539  C CA  . GLY D 1 87  ? 97.227  120.272 82.033  1.00 64.90  ? 33  GLY D CA  1 
ATOM   8540  C C   . GLY D 1 87  ? 97.048  119.892 83.488  1.00 67.04  ? 33  GLY D C   1 
ATOM   8541  O O   . GLY D 1 87  ? 97.143  120.730 84.391  1.00 66.11  ? 33  GLY D O   1 
ATOM   8542  N N   . PRO D 1 88  ? 96.777  118.616 83.741  1.00 71.02  ? 34  PRO D N   1 
ATOM   8543  C CA  . PRO D 1 88  ? 96.612  118.142 85.120  1.00 69.42  ? 34  PRO D CA  1 
ATOM   8544  C C   . PRO D 1 88  ? 97.888  118.330 85.918  1.00 69.67  ? 34  PRO D C   1 
ATOM   8545  O O   . PRO D 1 88  ? 98.994  118.284 85.358  1.00 72.49  ? 34  PRO D O   1 
ATOM   8546  C CB  . PRO D 1 88  ? 96.279  116.652 84.945  1.00 67.78  ? 34  PRO D CB  1 
ATOM   8547  C CG  . PRO D 1 88  ? 95.786  116.528 83.540  1.00 72.40  ? 34  PRO D CG  1 
ATOM   8548  C CD  . PRO D 1 88  ? 96.557  117.544 82.757  1.00 71.15  ? 34  PRO D CD  1 
ATOM   8549  N N   . PRO D 1 89  ? 97.778  118.557 87.224  1.00 65.55  ? 35  PRO D N   1 
ATOM   8550  C CA  . PRO D 1 89  ? 98.979  118.719 88.048  1.00 61.63  ? 35  PRO D CA  1 
ATOM   8551  C C   . PRO D 1 89  ? 99.820  117.455 88.076  1.00 59.71  ? 35  PRO D C   1 
ATOM   8552  O O   . PRO D 1 89  ? 99.307  116.334 88.027  1.00 60.91  ? 35  PRO D O   1 
ATOM   8553  C CB  . PRO D 1 89  ? 98.414  119.040 89.437  1.00 58.80  ? 35  PRO D CB  1 
ATOM   8554  C CG  . PRO D 1 89  ? 97.039  118.467 89.422  1.00 59.00  ? 35  PRO D CG  1 
ATOM   8555  C CD  . PRO D 1 89  ? 96.544  118.654 88.021  1.00 63.72  ? 35  PRO D CD  1 
ATOM   8556  N N   . VAL D 1 90  ? 101.131 117.649 88.165  1.00 54.95  ? 36  VAL D N   1 
ATOM   8557  C CA  . VAL D 1 90  ? 102.085 116.547 88.196  1.00 55.95  ? 36  VAL D CA  1 
ATOM   8558  C C   . VAL D 1 90  ? 102.207 116.063 89.637  1.00 59.53  ? 36  VAL D C   1 
ATOM   8559  O O   . VAL D 1 90  ? 102.664 116.799 90.514  1.00 58.19  ? 36  VAL D O   1 
ATOM   8560  C CB  . VAL D 1 90  ? 103.445 116.964 87.624  1.00 55.04  ? 36  VAL D CB  1 
ATOM   8561  C CG1 . VAL D 1 90  ? 103.817 118.363 88.088  1.00 51.36  ? 36  VAL D CG1 1 
ATOM   8562  C CG2 . VAL D 1 90  ? 104.520 115.964 88.021  1.00 53.85  ? 36  VAL D CG2 1 
ATOM   8563  N N   . CYS D 1 91  ? 101.781 114.827 89.886  1.00 62.91  ? 37  CYS D N   1 
ATOM   8564  C CA  . CYS D 1 91  ? 101.929 114.245 91.211  1.00 56.88  ? 37  CYS D CA  1 
ATOM   8565  C C   . CYS D 1 91  ? 103.398 113.974 91.505  1.00 53.61  ? 37  CYS D C   1 
ATOM   8566  O O   . CYS D 1 91  ? 104.135 113.471 90.653  1.00 56.15  ? 37  CYS D O   1 
ATOM   8567  C CB  . CYS D 1 91  ? 101.121 112.953 91.322  1.00 54.15  ? 37  CYS D CB  1 
ATOM   8568  S SG  . CYS D 1 91  ? 99.333  113.172 91.194  1.00 64.97  ? 37  CYS D SG  1 
ATOM   8569  N N   . VAL D 1 92  ? 103.823 114.310 92.721  1.00 47.68  ? 38  VAL D N   1 
ATOM   8570  C CA  . VAL D 1 92  ? 105.216 114.167 93.143  1.00 44.28  ? 38  VAL D CA  1 
ATOM   8571  C C   . VAL D 1 92  ? 105.197 113.416 94.471  1.00 47.34  ? 38  VAL D C   1 
ATOM   8572  O O   . VAL D 1 92  ? 104.981 114.005 95.534  1.00 52.70  ? 38  VAL D O   1 
ATOM   8573  C CB  . VAL D 1 92  ? 105.934 115.513 93.282  1.00 39.59  ? 38  VAL D CB  1 
ATOM   8574  C CG1 . VAL D 1 92  ? 107.386 115.299 93.672  1.00 39.70  ? 38  VAL D CG1 1 
ATOM   8575  C CG2 . VAL D 1 92  ? 105.841 116.309 91.992  1.00 43.54  ? 38  VAL D CG2 1 
ATOM   8576  N N   . GLY D 1 93  ? 105.421 112.105 94.419  1.00 44.61  ? 39  GLY D N   1 
ATOM   8577  C CA  . GLY D 1 93  ? 105.550 111.338 95.639  1.00 44.95  ? 39  GLY D CA  1 
ATOM   8578  C C   . GLY D 1 93  ? 106.884 111.582 96.314  1.00 47.16  ? 39  GLY D C   1 
ATOM   8579  O O   . GLY D 1 93  ? 107.856 112.003 95.694  1.00 48.61  ? 39  GLY D O   1 
ATOM   8580  N N   . MET D 1 94  ? 106.935 111.318 97.615  1.00 47.71  ? 40  MET D N   1 
ATOM   8581  C CA  . MET D 1 94  ? 108.136 111.607 98.383  1.00 45.89  ? 40  MET D CA  1 
ATOM   8582  C C   . MET D 1 94  ? 108.428 110.493 99.373  1.00 43.24  ? 40  MET D C   1 
ATOM   8583  O O   . MET D 1 94  ? 107.523 109.802 99.843  1.00 42.66  ? 40  MET D O   1 
ATOM   8584  C CB  . MET D 1 94  ? 108.014 112.929 99.146  1.00 44.88  ? 40  MET D CB  1 
ATOM   8585  C CG  . MET D 1 94  ? 107.873 114.140 98.258  1.00 45.42  ? 40  MET D CG  1 
ATOM   8586  S SD  . MET D 1 94  ? 107.814 115.670 99.193  1.00 60.59  ? 40  MET D SD  1 
ATOM   8587  C CE  . MET D 1 94  ? 107.757 116.846 97.851  1.00 50.70  ? 40  MET D CE  1 
ATOM   8588  N N   A ASN D 1 95  ? 109.718 110.327 99.675  0.50 47.20  ? 41  ASN D N   1 
ATOM   8589  N N   B ASN D 1 95  ? 109.707 110.328 99.691  0.50 47.32  ? 41  ASN D N   1 
ATOM   8590  C CA  A ASN D 1 95  ? 110.196 109.408 100.699 0.50 48.20  ? 41  ASN D CA  1 
ATOM   8591  C CA  B ASN D 1 95  ? 110.078 109.469 100.802 0.50 48.03  ? 41  ASN D CA  1 
ATOM   8592  C C   A ASN D 1 95  ? 111.320 110.075 101.479 0.50 47.34  ? 41  ASN D C   1 
ATOM   8593  C C   B ASN D 1 95  ? 111.309 110.046 101.479 0.50 47.34  ? 41  ASN D C   1 
ATOM   8594  O O   A ASN D 1 95  ? 112.044 110.921 100.947 0.50 46.39  ? 41  ASN D O   1 
ATOM   8595  O O   B ASN D 1 95  ? 112.069 110.820 100.891 0.50 46.19  ? 41  ASN D O   1 
ATOM   8596  C CB  A ASN D 1 95  ? 110.705 108.091 100.098 0.50 49.28  ? 41  ASN D CB  1 
ATOM   8597  C CB  B ASN D 1 95  ? 110.308 108.016 100.362 0.50 48.53  ? 41  ASN D CB  1 
ATOM   8598  C CG  A ASN D 1 95  ? 109.846 107.599 98.953  0.50 51.41  ? 41  ASN D CG  1 
ATOM   8599  C CG  B ASN D 1 95  ? 111.123 107.907 99.097  0.50 50.41  ? 41  ASN D CG  1 
ATOM   8600  O OD1 A ASN D 1 95  ? 110.080 107.943 97.795  0.50 52.87  ? 41  ASN D OD1 1 
ATOM   8601  O OD1 B ASN D 1 95  ? 110.581 107.932 97.994  0.50 52.64  ? 41  ASN D OD1 1 
ATOM   8602  N ND2 A ASN D 1 95  ? 108.846 106.786 99.271  0.50 49.99  ? 41  ASN D ND2 1 
ATOM   8603  N ND2 B ASN D 1 95  ? 112.433 107.769 99.249  0.50 49.63  ? 41  ASN D ND2 1 
ATOM   8604  N N   . ILE D 1 96  ? 111.473 109.680 102.743 1.00 47.32  ? 42  ILE D N   1 
ATOM   8605  C CA  . ILE D 1 96  ? 112.545 110.180 103.591 1.00 44.69  ? 42  ILE D CA  1 
ATOM   8606  C C   . ILE D 1 96  ? 113.208 108.990 104.265 1.00 51.80  ? 42  ILE D C   1 
ATOM   8607  O O   . ILE D 1 96  ? 112.522 108.108 104.790 1.00 55.71  ? 42  ILE D O   1 
ATOM   8608  C CB  . ILE D 1 96  ? 112.027 111.183 104.641 1.00 42.85  ? 42  ILE D CB  1 
ATOM   8609  C CG1 . ILE D 1 96  ? 111.446 112.422 103.961 1.00 39.97  ? 42  ILE D CG1 1 
ATOM   8610  C CG2 . ILE D 1 96  ? 113.134 111.578 105.602 1.00 42.34  ? 42  ILE D CG2 1 
ATOM   8611  C CD1 . ILE D 1 96  ? 110.952 113.473 104.925 1.00 37.47  ? 42  ILE D CD1 1 
ATOM   8612  N N   . ASP D 1 97  ? 114.535 108.962 104.245 1.00 48.67  ? 43  ASP D N   1 
ATOM   8613  C CA  . ASP D 1 97  ? 115.319 107.966 104.969 1.00 45.92  ? 43  ASP D CA  1 
ATOM   8614  C C   . ASP D 1 97  ? 116.144 108.734 105.994 1.00 48.53  ? 43  ASP D C   1 
ATOM   8615  O O   . ASP D 1 97  ? 117.153 109.351 105.648 1.00 52.46  ? 43  ASP D O   1 
ATOM   8616  C CB  . ASP D 1 97  ? 116.198 107.158 104.021 1.00 45.90  ? 43  ASP D CB  1 
ATOM   8617  C CG  . ASP D 1 97  ? 116.788 105.928 104.678 1.00 59.39  ? 43  ASP D CG  1 
ATOM   8618  O OD1 . ASP D 1 97  ? 116.541 105.716 105.883 1.00 63.43  ? 43  ASP D OD1 1 
ATOM   8619  O OD2 . ASP D 1 97  ? 117.496 105.168 103.986 1.00 64.01  ? 43  ASP D OD2 1 
ATOM   8620  N N   . ILE D 1 98  ? 115.708 108.714 107.249 1.00 47.71  ? 44  ILE D N   1 
ATOM   8621  C CA  . ILE D 1 98  ? 116.322 109.538 108.284 1.00 44.65  ? 44  ILE D CA  1 
ATOM   8622  C C   . ILE D 1 98  ? 117.647 108.902 108.687 1.00 51.04  ? 44  ILE D C   1 
ATOM   8623  O O   . ILE D 1 98  ? 117.674 107.804 109.247 1.00 55.54  ? 44  ILE D O   1 
ATOM   8624  C CB  . ILE D 1 98  ? 115.397 109.699 109.492 1.00 44.26  ? 44  ILE D CB  1 
ATOM   8625  C CG1 . ILE D 1 98  ? 114.124 110.442 109.089 1.00 42.10  ? 44  ILE D CG1 1 
ATOM   8626  C CG2 . ILE D 1 98  ? 116.118 110.429 110.604 1.00 46.31  ? 44  ILE D CG2 1 
ATOM   8627  C CD1 . ILE D 1 98  ? 113.138 110.609 110.214 1.00 49.48  ? 44  ILE D CD1 1 
ATOM   8628  N N   . ALA D 1 99  ? 118.754 109.591 108.398 1.00 47.39  ? 45  ALA D N   1 
ATOM   8629  C CA  . ALA D 1 99  ? 120.059 109.067 108.779 1.00 50.71  ? 45  ALA D CA  1 
ATOM   8630  C C   . ALA D 1 99  ? 120.283 109.190 110.279 1.00 55.88  ? 45  ALA D C   1 
ATOM   8631  O O   . ALA D 1 99  ? 120.760 108.245 110.919 1.00 65.84  ? 45  ALA D O   1 
ATOM   8632  C CB  . ALA D 1 99  ? 121.161 109.790 108.008 1.00 44.59  ? 45  ALA D CB  1 
ATOM   8633  N N   . SER D 1 100 ? 119.936 110.336 110.858 1.00 49.08  ? 46  SER D N   1 
ATOM   8634  C CA  . SER D 1 100 ? 120.152 110.587 112.278 1.00 53.58  ? 46  SER D CA  1 
ATOM   8635  C C   . SER D 1 100 ? 119.465 111.890 112.659 1.00 52.41  ? 46  SER D C   1 
ATOM   8636  O O   . SER D 1 100 ? 119.069 112.682 111.801 1.00 54.62  ? 46  SER D O   1 
ATOM   8637  C CB  . SER D 1 100 ? 121.644 110.652 112.616 1.00 58.54  ? 46  SER D CB  1 
ATOM   8638  O OG  . SER D 1 100 ? 122.283 111.682 111.881 1.00 55.08  ? 46  SER D OG  1 
ATOM   8639  N N   . ILE D 1 101 ? 119.330 112.097 113.965 1.00 53.54  ? 47  ILE D N   1 
ATOM   8640  C CA  . ILE D 1 101 ? 118.913 113.370 114.541 1.00 55.36  ? 47  ILE D CA  1 
ATOM   8641  C C   . ILE D 1 101 ? 120.092 113.851 115.373 1.00 61.06  ? 47  ILE D C   1 
ATOM   8642  O O   . ILE D 1 101 ? 120.367 113.309 116.449 1.00 71.11  ? 47  ILE D O   1 
ATOM   8643  C CB  . ILE D 1 101 ? 117.640 113.247 115.384 1.00 53.34  ? 47  ILE D CB  1 
ATOM   8644  C CG1 . ILE D 1 101 ? 116.457 112.833 114.508 1.00 50.96  ? 47  ILE D CG1 1 
ATOM   8645  C CG2 . ILE D 1 101 ? 117.350 114.555 116.104 1.00 50.12  ? 47  ILE D CG2 1 
ATOM   8646  C CD1 . ILE D 1 101 ? 115.134 112.809 115.238 1.00 52.95  ? 47  ILE D CD1 1 
ATOM   8647  N N   . ASP D 1 102 ? 120.801 114.865 114.874 1.00 59.56  ? 48  ASP D N   1 
ATOM   8648  C CA  . ASP D 1 102 ? 122.093 115.223 115.452 1.00 63.06  ? 48  ASP D CA  1 
ATOM   8649  C C   . ASP D 1 102 ? 121.943 115.806 116.851 1.00 64.79  ? 48  ASP D C   1 
ATOM   8650  O O   . ASP D 1 102 ? 122.636 115.386 117.784 1.00 73.94  ? 48  ASP D O   1 
ATOM   8651  C CB  . ASP D 1 102 ? 122.819 116.202 114.533 1.00 67.56  ? 48  ASP D CB  1 
ATOM   8652  C CG  . ASP D 1 102 ? 122.974 115.667 113.125 1.00 74.91  ? 48  ASP D CG  1 
ATOM   8653  O OD1 . ASP D 1 102 ? 122.430 114.579 112.844 1.00 68.85  ? 48  ASP D OD1 1 
ATOM   8654  O OD2 . ASP D 1 102 ? 123.638 116.330 112.302 1.00 76.83  ? 48  ASP D OD2 1 
ATOM   8655  N N   . MET D 1 103 ? 121.041 116.768 117.023 1.00 59.05  ? 49  MET D N   1 
ATOM   8656  C CA  . MET D 1 103 ? 120.910 117.420 118.318 1.00 61.92  ? 49  MET D CA  1 
ATOM   8657  C C   . MET D 1 103 ? 119.522 118.026 118.447 1.00 59.46  ? 49  MET D C   1 
ATOM   8658  O O   . MET D 1 103 ? 118.852 118.317 117.454 1.00 63.18  ? 49  MET D O   1 
ATOM   8659  C CB  . MET D 1 103 ? 121.979 118.499 118.513 1.00 61.40  ? 49  MET D CB  1 
ATOM   8660  C CG  . MET D 1 103 ? 121.700 119.783 117.752 1.00 68.82  ? 49  MET D CG  1 
ATOM   8661  S SD  . MET D 1 103 ? 123.021 120.997 117.907 1.00 104.24 ? 49  MET D SD  1 
ATOM   8662  C CE  . MET D 1 103 ? 124.346 120.162 117.040 1.00 75.30  ? 49  MET D CE  1 
ATOM   8663  N N   . VAL D 1 104 ? 119.107 118.205 119.697 1.00 56.87  ? 50  VAL D N   1 
ATOM   8664  C CA  . VAL D 1 104 ? 117.865 118.878 120.053 1.00 54.91  ? 50  VAL D CA  1 
ATOM   8665  C C   . VAL D 1 104 ? 118.208 119.953 121.073 1.00 61.86  ? 50  VAL D C   1 
ATOM   8666  O O   . VAL D 1 104 ? 118.834 119.658 122.097 1.00 69.69  ? 50  VAL D O   1 
ATOM   8667  C CB  . VAL D 1 104 ? 116.826 117.891 120.619 1.00 51.34  ? 50  VAL D CB  1 
ATOM   8668  C CG1 . VAL D 1 104 ? 115.607 118.630 121.124 1.00 52.79  ? 50  VAL D CG1 1 
ATOM   8669  C CG2 . VAL D 1 104 ? 116.436 116.869 119.565 1.00 52.08  ? 50  VAL D CG2 1 
ATOM   8670  N N   . SER D 1 105 ? 117.811 121.193 120.799 1.00 62.73  ? 51  SER D N   1 
ATOM   8671  C CA  . SER D 1 105 ? 118.214 122.330 121.614 1.00 66.13  ? 51  SER D CA  1 
ATOM   8672  C C   . SER D 1 105 ? 116.989 123.112 122.057 1.00 68.68  ? 51  SER D C   1 
ATOM   8673  O O   . SER D 1 105 ? 116.127 123.443 121.236 1.00 70.45  ? 51  SER D O   1 
ATOM   8674  C CB  . SER D 1 105 ? 119.172 123.244 120.843 1.00 68.46  ? 51  SER D CB  1 
ATOM   8675  O OG  . SER D 1 105 ? 119.497 124.399 121.596 1.00 76.11  ? 51  SER D OG  1 
ATOM   8676  N N   . GLU D 1 106 ? 116.920 123.405 123.355 1.00 68.12  ? 52  GLU D N   1 
ATOM   8677  C CA  . GLU D 1 106 ? 115.892 124.272 123.914 1.00 67.77  ? 52  GLU D CA  1 
ATOM   8678  C C   . GLU D 1 106 ? 116.323 125.727 123.986 1.00 72.80  ? 52  GLU D C   1 
ATOM   8679  O O   . GLU D 1 106 ? 115.466 126.614 124.049 1.00 76.55  ? 52  GLU D O   1 
ATOM   8680  C CB  . GLU D 1 106 ? 115.495 123.797 125.317 1.00 72.98  ? 52  GLU D CB  1 
ATOM   8681  C CG  . GLU D 1 106 ? 114.815 122.434 125.360 1.00 75.99  ? 52  GLU D CG  1 
ATOM   8682  C CD  . GLU D 1 106 ? 115.791 121.277 125.247 1.00 80.97  ? 52  GLU D CD  1 
ATOM   8683  O OE1 . GLU D 1 106 ? 117.016 121.525 125.237 1.00 81.72  ? 52  GLU D OE1 1 
ATOM   8684  O OE2 . GLU D 1 106 ? 115.332 120.118 125.170 1.00 80.61  ? 52  GLU D OE2 1 
ATOM   8685  N N   . VAL D 1 107 ? 117.633 125.988 123.986 1.00 75.80  ? 53  VAL D N   1 
ATOM   8686  C CA  . VAL D 1 107 ? 118.124 127.363 123.932 1.00 79.61  ? 53  VAL D CA  1 
ATOM   8687  C C   . VAL D 1 107 ? 117.661 128.034 122.646 1.00 80.81  ? 53  VAL D C   1 
ATOM   8688  O O   . VAL D 1 107 ? 117.187 129.176 122.652 1.00 85.38  ? 53  VAL D O   1 
ATOM   8689  C CB  . VAL D 1 107 ? 119.658 127.386 124.059 1.00 80.32  ? 53  VAL D CB  1 
ATOM   8690  C CG1 . VAL D 1 107 ? 120.164 128.814 124.194 1.00 85.31  ? 53  VAL D CG1 1 
ATOM   8691  C CG2 . VAL D 1 107 ? 120.100 126.537 125.237 1.00 85.18  ? 53  VAL D CG2 1 
ATOM   8692  N N   . ASN D 1 108 ? 117.791 127.331 121.523 1.00 74.22  ? 54  ASN D N   1 
ATOM   8693  C CA  . ASN D 1 108 ? 117.279 127.799 120.244 1.00 69.97  ? 54  ASN D CA  1 
ATOM   8694  C C   . ASN D 1 108 ? 115.929 127.192 119.888 1.00 67.68  ? 54  ASN D C   1 
ATOM   8695  O O   . ASN D 1 108 ? 115.269 127.691 118.969 1.00 70.47  ? 54  ASN D O   1 
ATOM   8696  C CB  . ASN D 1 108 ? 118.282 127.492 119.127 1.00 70.99  ? 54  ASN D CB  1 
ATOM   8697  C CG  . ASN D 1 108 ? 119.580 128.258 119.280 1.00 78.01  ? 54  ASN D CG  1 
ATOM   8698  O OD1 . ASN D 1 108 ? 119.580 129.440 119.619 1.00 86.11  ? 54  ASN D OD1 1 
ATOM   8699  N ND2 . ASN D 1 108 ? 120.696 127.586 119.028 1.00 79.40  ? 54  ASN D ND2 1 
ATOM   8700  N N   . MET D 1 109 ? 115.512 126.136 120.588 1.00 67.94  ? 55  MET D N   1 
ATOM   8701  C CA  . MET D 1 109 ? 114.258 125.431 120.318 1.00 70.28  ? 55  MET D CA  1 
ATOM   8702  C C   . MET D 1 109 ? 114.211 124.932 118.874 1.00 69.84  ? 55  MET D C   1 
ATOM   8703  O O   . MET D 1 109 ? 113.341 125.302 118.082 1.00 69.76  ? 55  MET D O   1 
ATOM   8704  C CB  . MET D 1 109 ? 113.046 126.312 120.641 1.00 70.61  ? 55  MET D CB  1 
ATOM   8705  C CG  . MET D 1 109 ? 112.771 126.464 122.124 1.00 77.64  ? 55  MET D CG  1 
ATOM   8706  S SD  . MET D 1 109 ? 111.207 127.291 122.459 1.00 100.40 ? 55  MET D SD  1 
ATOM   8707  C CE  . MET D 1 109 ? 111.153 127.188 124.246 1.00 89.46  ? 55  MET D CE  1 
ATOM   8708  N N   . ASP D 1 110 ? 115.170 124.070 118.544 1.00 69.98  ? 56  ASP D N   1 
ATOM   8709  C CA  . ASP D 1 110 ? 115.257 123.513 117.202 1.00 61.61  ? 56  ASP D CA  1 
ATOM   8710  C C   . ASP D 1 110 ? 116.038 122.209 117.252 1.00 61.44  ? 56  ASP D C   1 
ATOM   8711  O O   . ASP D 1 110 ? 116.788 121.947 118.195 1.00 67.90  ? 56  ASP D O   1 
ATOM   8712  C CB  . ASP D 1 110 ? 115.906 124.502 116.225 1.00 62.48  ? 56  ASP D CB  1 
ATOM   8713  C CG  . ASP D 1 110 ? 117.249 125.014 116.713 1.00 70.41  ? 56  ASP D CG  1 
ATOM   8714  O OD1 . ASP D 1 110 ? 117.685 124.614 117.812 1.00 70.75  ? 56  ASP D OD1 1 
ATOM   8715  O OD2 . ASP D 1 110 ? 117.870 125.824 115.994 1.00 71.05  ? 56  ASP D OD2 1 
ATOM   8716  N N   . TYR D 1 111 ? 115.863 121.397 116.214 1.00 56.90  ? 57  TYR D N   1 
ATOM   8717  C CA  . TYR D 1 111 ? 116.538 120.111 116.128 1.00 51.52  ? 57  TYR D CA  1 
ATOM   8718  C C   . TYR D 1 111 ? 117.214 119.964 114.775 1.00 49.15  ? 57  TYR D C   1 
ATOM   8719  O O   . TYR D 1 111 ? 116.667 120.371 113.747 1.00 52.51  ? 57  TYR D O   1 
ATOM   8720  C CB  . TYR D 1 111 ? 115.564 118.948 116.364 1.00 47.44  ? 57  TYR D CB  1 
ATOM   8721  C CG  . TYR D 1 111 ? 114.476 118.806 115.325 1.00 46.84  ? 57  TYR D CG  1 
ATOM   8722  C CD1 . TYR D 1 111 ? 113.303 119.538 115.416 1.00 49.94  ? 57  TYR D CD1 1 
ATOM   8723  C CD2 . TYR D 1 111 ? 114.614 117.923 114.265 1.00 50.77  ? 57  TYR D CD2 1 
ATOM   8724  C CE1 . TYR D 1 111 ? 112.306 119.405 114.474 1.00 52.92  ? 57  TYR D CE1 1 
ATOM   8725  C CE2 . TYR D 1 111 ? 113.621 117.785 113.318 1.00 53.58  ? 57  TYR D CE2 1 
ATOM   8726  C CZ  . TYR D 1 111 ? 112.469 118.527 113.429 1.00 53.38  ? 57  TYR D CZ  1 
ATOM   8727  O OH  . TYR D 1 111 ? 111.475 118.395 112.490 1.00 59.01  ? 57  TYR D OH  1 
ATOM   8728  N N   . THR D 1 112 ? 118.403 119.370 114.786 1.00 49.85  ? 58  THR D N   1 
ATOM   8729  C CA  . THR D 1 112 ? 119.180 119.138 113.576 1.00 49.17  ? 58  THR D CA  1 
ATOM   8730  C C   . THR D 1 112 ? 118.911 117.723 113.084 1.00 50.38  ? 58  THR D C   1 
ATOM   8731  O O   . THR D 1 112 ? 119.157 116.751 113.805 1.00 59.46  ? 58  THR D O   1 
ATOM   8732  C CB  . THR D 1 112 ? 120.673 119.341 113.831 1.00 53.44  ? 58  THR D CB  1 
ATOM   8733  O OG1 . THR D 1 112 ? 120.911 120.700 114.218 1.00 53.03  ? 58  THR D OG1 1 
ATOM   8734  C CG2 . THR D 1 112 ? 121.466 119.034 112.576 1.00 53.00  ? 58  THR D CG2 1 
ATOM   8735  N N   . LEU D 1 113 ? 118.413 117.613 111.857 1.00 43.16  ? 59  LEU D N   1 
ATOM   8736  C CA  . LEU D 1 113 ? 117.955 116.352 111.296 1.00 41.58  ? 59  LEU D CA  1 
ATOM   8737  C C   . LEU D 1 113 ? 118.637 116.121 109.959 1.00 41.81  ? 59  LEU D C   1 
ATOM   8738  O O   . LEU D 1 113 ? 118.612 116.997 109.090 1.00 48.01  ? 59  LEU D O   1 
ATOM   8739  C CB  . LEU D 1 113 ? 116.434 116.368 111.128 1.00 39.82  ? 59  LEU D CB  1 
ATOM   8740  C CG  . LEU D 1 113 ? 115.796 115.245 110.320 1.00 42.21  ? 59  LEU D CG  1 
ATOM   8741  C CD1 . LEU D 1 113 ? 115.912 113.947 111.078 1.00 50.42  ? 59  LEU D CD1 1 
ATOM   8742  C CD2 . LEU D 1 113 ? 114.345 115.569 110.023 1.00 46.97  ? 59  LEU D CD2 1 
ATOM   8743  N N   . THR D 1 114 ? 119.236 114.947 109.789 1.00 38.83  ? 60  THR D N   1 
ATOM   8744  C CA  . THR D 1 114 ? 119.904 114.573 108.549 1.00 42.47  ? 60  THR D CA  1 
ATOM   8745  C C   . THR D 1 114 ? 119.106 113.473 107.868 1.00 42.30  ? 60  THR D C   1 
ATOM   8746  O O   . THR D 1 114 ? 118.721 112.490 108.510 1.00 48.82  ? 60  THR D O   1 
ATOM   8747  C CB  . THR D 1 114 ? 121.335 114.104 108.810 1.00 47.10  ? 60  THR D CB  1 
ATOM   8748  O OG1 . THR D 1 114 ? 122.028 115.087 109.587 1.00 48.58  ? 60  THR D OG1 1 
ATOM   8749  C CG2 . THR D 1 114 ? 122.071 113.902 107.499 1.00 37.03  ? 60  THR D CG2 1 
ATOM   8750  N N   . MET D 1 115 ? 118.866 113.627 106.569 1.00 35.12  ? 61  MET D N   1 
ATOM   8751  C CA  . MET D 1 115 ? 117.978 112.696 105.891 1.00 34.68  ? 61  MET D CA  1 
ATOM   8752  C C   . MET D 1 115 ? 118.347 112.562 104.423 1.00 38.48  ? 61  MET D C   1 
ATOM   8753  O O   . MET D 1 115 ? 119.002 113.427 103.836 1.00 43.15  ? 61  MET D O   1 
ATOM   8754  C CB  . MET D 1 115 ? 116.517 113.134 106.014 1.00 39.58  ? 61  MET D CB  1 
ATOM   8755  C CG  . MET D 1 115 ? 116.257 114.532 105.494 1.00 38.69  ? 61  MET D CG  1 
ATOM   8756  S SD  . MET D 1 115 ? 114.525 114.999 105.619 1.00 50.54  ? 61  MET D SD  1 
ATOM   8757  C CE  . MET D 1 115 ? 114.663 116.773 105.490 1.00 42.60  ? 61  MET D CE  1 
ATOM   8758  N N   . TYR D 1 116 ? 117.914 111.444 103.844 1.00 38.66  ? 62  TYR D N   1 
ATOM   8759  C CA  . TYR D 1 116 ? 117.893 111.233 102.403 1.00 37.03  ? 62  TYR D CA  1 
ATOM   8760  C C   . TYR D 1 116 ? 116.471 111.514 101.938 1.00 42.65  ? 62  TYR D C   1 
ATOM   8761  O O   . TYR D 1 116 ? 115.568 110.703 102.164 1.00 48.26  ? 62  TYR D O   1 
ATOM   8762  C CB  . TYR D 1 116 ? 118.302 109.808 102.037 1.00 37.54  ? 62  TYR D CB  1 
ATOM   8763  C CG  . TYR D 1 116 ? 119.634 109.351 102.582 1.00 38.54  ? 62  TYR D CG  1 
ATOM   8764  C CD1 . TYR D 1 116 ? 119.762 108.939 103.899 1.00 40.44  ? 62  TYR D CD1 1 
ATOM   8765  C CD2 . TYR D 1 116 ? 120.755 109.300 101.770 1.00 39.55  ? 62  TYR D CD2 1 
ATOM   8766  C CE1 . TYR D 1 116 ? 120.973 108.511 104.397 1.00 39.59  ? 62  TYR D CE1 1 
ATOM   8767  C CE2 . TYR D 1 116 ? 121.970 108.871 102.260 1.00 36.74  ? 62  TYR D CE2 1 
ATOM   8768  C CZ  . TYR D 1 116 ? 122.072 108.478 103.574 1.00 40.09  ? 62  TYR D CZ  1 
ATOM   8769  O OH  . TYR D 1 116 ? 123.281 108.050 104.069 1.00 47.02  ? 62  TYR D OH  1 
ATOM   8770  N N   . PHE D 1 117 ? 116.273 112.663 101.311 1.00 37.06  ? 63  PHE D N   1 
ATOM   8771  C CA  . PHE D 1 117 ? 114.970 113.096 100.833 1.00 38.89  ? 63  PHE D CA  1 
ATOM   8772  C C   . PHE D 1 117 ? 114.879 112.790 99.344  1.00 39.43  ? 63  PHE D C   1 
ATOM   8773  O O   . PHE D 1 117 ? 115.670 113.315 98.554  1.00 42.49  ? 63  PHE D O   1 
ATOM   8774  C CB  . PHE D 1 117 ? 114.790 114.588 101.110 1.00 35.86  ? 63  PHE D CB  1 
ATOM   8775  C CG  . PHE D 1 117 ? 113.517 115.161 100.580 1.00 35.60  ? 63  PHE D CG  1 
ATOM   8776  C CD1 . PHE D 1 117 ? 112.307 114.859 101.174 1.00 39.22  ? 63  PHE D CD1 1 
ATOM   8777  C CD2 . PHE D 1 117 ? 113.534 116.023 99.501  1.00 36.52  ? 63  PHE D CD2 1 
ATOM   8778  C CE1 . PHE D 1 117 ? 111.137 115.393 100.691 1.00 41.14  ? 63  PHE D CE1 1 
ATOM   8779  C CE2 . PHE D 1 117 ? 112.369 116.561 99.016  1.00 39.68  ? 63  PHE D CE2 1 
ATOM   8780  C CZ  . PHE D 1 117 ? 111.168 116.246 99.610  1.00 41.21  ? 63  PHE D CZ  1 
ATOM   8781  N N   . GLN D 1 118 ? 113.932 111.935 98.959  1.00 40.34  ? 64  GLN D N   1 
ATOM   8782  C CA  . GLN D 1 118 ? 113.821 111.468 97.585  1.00 43.67  ? 64  GLN D CA  1 
ATOM   8783  C C   . GLN D 1 118 ? 112.450 111.818 97.031  1.00 45.04  ? 64  GLN D C   1 
ATOM   8784  O O   . GLN D 1 118 ? 111.430 111.593 97.693  1.00 49.88  ? 64  GLN D O   1 
ATOM   8785  C CB  . GLN D 1 118 ? 114.062 109.961 97.497  1.00 44.64  ? 64  GLN D CB  1 
ATOM   8786  C CG  . GLN D 1 118 ? 115.392 109.521 98.075  1.00 47.32  ? 64  GLN D CG  1 
ATOM   8787  C CD  . GLN D 1 118 ? 115.576 108.022 98.034  1.00 60.12  ? 64  GLN D CD  1 
ATOM   8788  O OE1 . GLN D 1 118 ? 114.711 107.292 97.551  1.00 63.55  ? 64  GLN D OE1 1 
ATOM   8789  N NE2 . GLN D 1 118 ? 116.708 107.551 98.542  1.00 63.95  ? 64  GLN D NE2 1 
ATOM   8790  N N   . GLN D 1 119 ? 112.435 112.367 95.819  1.00 39.62  ? 65  GLN D N   1 
ATOM   8791  C CA  . GLN D 1 119 ? 111.223 112.776 95.129  1.00 40.64  ? 65  GLN D CA  1 
ATOM   8792  C C   . GLN D 1 119 ? 111.033 111.922 93.884  1.00 44.23  ? 65  GLN D C   1 
ATOM   8793  O O   . GLN D 1 119 ? 111.994 111.608 93.175  1.00 46.30  ? 65  GLN D O   1 
ATOM   8794  C CB  . GLN D 1 119 ? 111.277 114.255 94.749  1.00 39.30  ? 65  GLN D CB  1 
ATOM   8795  C CG  . GLN D 1 119 ? 111.592 115.160 95.916  1.00 40.38  ? 65  GLN D CG  1 
ATOM   8796  C CD  . GLN D 1 119 ? 111.712 116.609 95.512  1.00 41.88  ? 65  GLN D CD  1 
ATOM   8797  O OE1 . GLN D 1 119 ? 110.791 117.181 94.933  1.00 44.15  ? 65  GLN D OE1 1 
ATOM   8798  N NE2 . GLN D 1 119 ? 112.854 117.213 95.811  1.00 43.55  ? 65  GLN D NE2 1 
ATOM   8799  N N   . TYR D 1 120 ? 109.779 111.570 93.621  1.00 45.23  ? 66  TYR D N   1 
ATOM   8800  C CA  A TYR D 1 120 ? 109.406 110.657 92.550  0.50 47.11  ? 66  TYR D CA  1 
ATOM   8801  C CA  B TYR D 1 120 ? 109.409 110.662 92.542  0.50 47.14  ? 66  TYR D CA  1 
ATOM   8802  C C   . TYR D 1 120 ? 108.331 111.327 91.708  1.00 46.04  ? 66  TYR D C   1 
ATOM   8803  O O   . TYR D 1 120 ? 107.233 111.590 92.207  1.00 53.20  ? 66  TYR D O   1 
ATOM   8804  C CB  A TYR D 1 120 ? 108.896 109.343 93.150  0.50 51.60  ? 66  TYR D CB  1 
ATOM   8805  C CB  B TYR D 1 120 ? 108.892 109.326 93.086  0.50 51.55  ? 66  TYR D CB  1 
ATOM   8806  C CG  A TYR D 1 120 ? 108.957 108.132 92.255  0.50 53.93  ? 66  TYR D CG  1 
ATOM   8807  C CG  B TYR D 1 120 ? 109.958 108.329 93.474  0.50 54.05  ? 66  TYR D CG  1 
ATOM   8808  C CD1 A TYR D 1 120 ? 110.142 107.430 92.085  0.50 54.61  ? 66  TYR D CD1 1 
ATOM   8809  C CD1 B TYR D 1 120 ? 110.395 107.370 92.573  0.50 54.64  ? 66  TYR D CD1 1 
ATOM   8810  C CD2 A TYR D 1 120 ? 107.820 107.665 91.611  0.50 53.91  ? 66  TYR D CD2 1 
ATOM   8811  C CD2 B TYR D 1 120 ? 110.509 108.332 94.748  0.50 52.48  ? 66  TYR D CD2 1 
ATOM   8812  C CE1 A TYR D 1 120 ? 110.199 106.311 91.278  0.50 57.49  ? 66  TYR D CE1 1 
ATOM   8813  C CE1 B TYR D 1 120 ? 111.362 106.449 92.924  0.50 55.72  ? 66  TYR D CE1 1 
ATOM   8814  C CE2 A TYR D 1 120 ? 107.866 106.547 90.805  0.50 54.95  ? 66  TYR D CE2 1 
ATOM   8815  C CE2 B TYR D 1 120 ? 111.475 107.413 95.108  0.50 52.03  ? 66  TYR D CE2 1 
ATOM   8816  C CZ  A TYR D 1 120 ? 109.058 105.873 90.643  0.50 58.20  ? 66  TYR D CZ  1 
ATOM   8817  C CZ  B TYR D 1 120 ? 111.898 106.475 94.193  0.50 55.66  ? 66  TYR D CZ  1 
ATOM   8818  O OH  A TYR D 1 120 ? 109.109 104.760 89.836  0.50 61.70  ? 66  TYR D OH  1 
ATOM   8819  O OH  B TYR D 1 120 ? 112.862 105.560 94.547  0.50 58.58  ? 66  TYR D OH  1 
ATOM   8820  N N   . TRP D 1 121 ? 108.633 111.603 90.440  1.00 44.29  ? 67  TRP D N   1 
ATOM   8821  C CA  . TRP D 1 121 ? 107.619 112.219 89.590  1.00 44.00  ? 67  TRP D CA  1 
ATOM   8822  C C   . TRP D 1 121 ? 107.736 111.668 88.177  1.00 48.92  ? 67  TRP D C   1 
ATOM   8823  O O   . TRP D 1 121 ? 108.581 110.821 87.887  1.00 58.18  ? 67  TRP D O   1 
ATOM   8824  C CB  . TRP D 1 121 ? 107.705 113.752 89.624  1.00 45.41  ? 67  TRP D CB  1 
ATOM   8825  C CG  . TRP D 1 121 ? 108.842 114.365 88.875  1.00 43.19  ? 67  TRP D CG  1 
ATOM   8826  C CD1 . TRP D 1 121 ? 108.852 114.738 87.564  1.00 45.04  ? 67  TRP D CD1 1 
ATOM   8827  C CD2 . TRP D 1 121 ? 110.122 114.720 89.403  1.00 41.90  ? 67  TRP D CD2 1 
ATOM   8828  N NE1 . TRP D 1 121 ? 110.066 115.289 87.238  1.00 46.60  ? 67  TRP D NE1 1 
ATOM   8829  C CE2 . TRP D 1 121 ? 110.865 115.288 88.351  1.00 44.07  ? 67  TRP D CE2 1 
ATOM   8830  C CE3 . TRP D 1 121 ? 110.717 114.603 90.661  1.00 41.42  ? 67  TRP D CE3 1 
ATOM   8831  C CZ2 . TRP D 1 121 ? 112.171 115.735 88.517  1.00 43.31  ? 67  TRP D CZ2 1 
ATOM   8832  C CZ3 . TRP D 1 121 ? 112.010 115.048 90.825  1.00 44.73  ? 67  TRP D CZ3 1 
ATOM   8833  C CH2 . TRP D 1 121 ? 112.725 115.607 89.759  1.00 42.26  ? 67  TRP D CH2 1 
ATOM   8834  N N   . ARG D 1 122 ? 106.853 112.133 87.295  1.00 49.98  ? 68  ARG D N   1 
ATOM   8835  C CA  . ARG D 1 122 ? 106.772 111.629 85.930  1.00 59.50  ? 68  ARG D CA  1 
ATOM   8836  C C   . ARG D 1 122 ? 106.885 112.795 84.962  1.00 62.69  ? 68  ARG D C   1 
ATOM   8837  O O   . ARG D 1 122 ? 106.120 113.760 85.057  1.00 68.60  ? 68  ARG D O   1 
ATOM   8838  C CB  . ARG D 1 122 ? 105.464 110.864 85.704  1.00 61.69  ? 68  ARG D CB  1 
ATOM   8839  C CG  . ARG D 1 122 ? 105.381 110.150 84.367  1.00 62.86  ? 68  ARG D CG  1 
ATOM   8840  C CD  . ARG D 1 122 ? 104.177 109.222 84.320  1.00 74.50  ? 68  ARG D CD  1 
ATOM   8841  N NE  . ARG D 1 122 ? 104.145 108.423 83.101  1.00 94.45  ? 68  ARG D NE  1 
ATOM   8842  C CZ  . ARG D 1 122 ? 103.269 107.458 82.862  1.00 97.41  ? 68  ARG D CZ  1 
ATOM   8843  N NH1 . ARG D 1 122 ? 102.332 107.141 83.741  1.00 98.19  ? 68  ARG D NH1 1 
ATOM   8844  N NH2 . ARG D 1 122 ? 103.335 106.791 81.713  1.00 96.43  ? 68  ARG D NH2 1 
ATOM   8845  N N   . ASP D 1 123 ? 107.838 112.707 84.037  1.00 59.95  ? 69  ASP D N   1 
ATOM   8846  C CA  . ASP D 1 123 ? 108.038 113.716 83.003  1.00 60.10  ? 69  ASP D CA  1 
ATOM   8847  C C   . ASP D 1 123 ? 108.026 113.011 81.654  1.00 68.86  ? 69  ASP D C   1 
ATOM   8848  O O   . ASP D 1 123 ? 108.981 112.306 81.313  1.00 71.68  ? 69  ASP D O   1 
ATOM   8849  C CB  . ASP D 1 123 ? 109.349 114.473 83.216  1.00 60.05  ? 69  ASP D CB  1 
ATOM   8850  C CG  . ASP D 1 123 ? 109.348 115.840 82.563  1.00 65.40  ? 69  ASP D CG  1 
ATOM   8851  O OD1 . ASP D 1 123 ? 108.585 116.042 81.595  1.00 67.64  ? 69  ASP D OD1 1 
ATOM   8852  O OD2 . ASP D 1 123 ? 110.112 116.716 83.020  1.00 64.91  ? 69  ASP D OD2 1 
ATOM   8853  N N   . LYS D 1 124 ? 106.947 113.200 80.889  1.00 71.21  ? 70  LYS D N   1 
ATOM   8854  C CA  . LYS D 1 124 ? 106.832 112.541 79.591  1.00 69.14  ? 70  LYS D CA  1 
ATOM   8855  C C   . LYS D 1 124 ? 107.943 112.966 78.642  1.00 67.06  ? 70  LYS D C   1 
ATOM   8856  O O   . LYS D 1 124 ? 108.290 112.220 77.719  1.00 71.35  ? 70  LYS D O   1 
ATOM   8857  C CB  . LYS D 1 124 ? 105.467 112.836 78.970  1.00 65.08  ? 70  LYS D CB  1 
ATOM   8858  C CG  . LYS D 1 124 ? 104.294 112.308 79.771  1.00 68.28  ? 70  LYS D CG  1 
ATOM   8859  C CD  . LYS D 1 124 ? 102.977 112.702 79.129  1.00 76.12  ? 70  LYS D CD  1 
ATOM   8860  C CE  . LYS D 1 124 ? 101.793 112.207 79.942  1.00 84.23  ? 70  LYS D CE  1 
ATOM   8861  N NZ  . LYS D 1 124 ? 100.501 112.654 79.354  1.00 84.47  ? 70  LYS D NZ  1 
ATOM   8862  N N   . ARG D 1 125 ? 108.512 114.152 78.849  1.00 65.16  ? 71  ARG D N   1 
ATOM   8863  C CA  . ARG D 1 125 ? 109.600 114.629 78.007  1.00 67.47  ? 71  ARG D CA  1 
ATOM   8864  C C   . ARG D 1 125 ? 110.914 113.912 78.279  1.00 70.34  ? 71  ARG D C   1 
ATOM   8865  O O   . ARG D 1 125 ? 111.885 114.143 77.552  1.00 72.10  ? 71  ARG D O   1 
ATOM   8866  C CB  . ARG D 1 125 ? 109.785 116.131 78.201  1.00 63.33  ? 71  ARG D CB  1 
ATOM   8867  C CG  . ARG D 1 125 ? 108.498 116.927 78.114  1.00 61.51  ? 71  ARG D CG  1 
ATOM   8868  C CD  . ARG D 1 125 ? 108.681 118.300 78.720  1.00 55.75  ? 71  ARG D CD  1 
ATOM   8869  N NE  . ARG D 1 125 ? 109.149 118.211 80.098  1.00 59.49  ? 71  ARG D NE  1 
ATOM   8870  C CZ  . ARG D 1 125 ? 109.422 119.256 80.866  1.00 61.85  ? 71  ARG D CZ  1 
ATOM   8871  N NH1 . ARG D 1 125 ? 109.276 120.494 80.424  1.00 61.74  ? 71  ARG D NH1 1 
ATOM   8872  N NH2 . ARG D 1 125 ? 109.853 119.053 82.107  1.00 63.09  ? 71  ARG D NH2 1 
ATOM   8873  N N   . LEU D 1 126 ? 110.972 113.063 79.300  1.00 68.53  ? 72  LEU D N   1 
ATOM   8874  C CA  . LEU D 1 126 ? 112.181 112.338 79.672  1.00 69.84  ? 72  LEU D CA  1 
ATOM   8875  C C   . LEU D 1 126 ? 111.984 110.836 79.518  1.00 76.36  ? 72  LEU D C   1 
ATOM   8876  O O   . LEU D 1 126 ? 112.405 110.045 80.364  1.00 78.89  ? 72  LEU D O   1 
ATOM   8877  C CB  . LEU D 1 126 ? 112.603 112.682 81.097  1.00 68.20  ? 72  LEU D CB  1 
ATOM   8878  C CG  . LEU D 1 126 ? 113.082 114.115 81.320  1.00 66.03  ? 72  LEU D CG  1 
ATOM   8879  C CD1 . LEU D 1 126 ? 113.310 114.379 82.796  1.00 64.71  ? 72  LEU D CD1 1 
ATOM   8880  C CD2 . LEU D 1 126 ? 114.352 114.371 80.529  1.00 66.19  ? 72  LEU D CD2 1 
ATOM   8881  N N   . ALA D 1 127 ? 111.341 110.428 78.429  1.00 76.93  ? 73  ALA D N   1 
ATOM   8882  C CA  . ALA D 1 127 ? 111.095 109.023 78.134  1.00 77.72  ? 73  ALA D CA  1 
ATOM   8883  C C   . ALA D 1 127 ? 111.995 108.585 76.989  1.00 80.91  ? 73  ALA D C   1 
ATOM   8884  O O   . ALA D 1 127 ? 112.010 109.218 75.928  1.00 78.98  ? 73  ALA D O   1 
ATOM   8885  C CB  . ALA D 1 127 ? 109.627 108.788 77.775  1.00 72.99  ? 73  ALA D CB  1 
ATOM   8886  N N   . TYR D 1 128 ? 112.741 107.505 77.206  1.00 79.52  ? 74  TYR D N   1 
ATOM   8887  C CA  . TYR D 1 128 ? 113.665 106.976 76.216  1.00 80.32  ? 74  TYR D CA  1 
ATOM   8888  C C   . TYR D 1 128 ? 113.215 105.590 75.775  1.00 88.23  ? 74  TYR D C   1 
ATOM   8889  O O   . TYR D 1 128 ? 112.641 104.826 76.556  1.00 86.09  ? 74  TYR D O   1 
ATOM   8890  C CB  . TYR D 1 128 ? 115.098 106.915 76.765  1.00 77.91  ? 74  TYR D CB  1 
ATOM   8891  C CG  . TYR D 1 128 ? 115.230 106.210 78.097  1.00 78.98  ? 74  TYR D CG  1 
ATOM   8892  C CD1 . TYR D 1 128 ? 115.421 104.837 78.164  1.00 83.31  ? 74  TYR D CD1 1 
ATOM   8893  C CD2 . TYR D 1 128 ? 115.175 106.920 79.287  1.00 75.84  ? 74  TYR D CD2 1 
ATOM   8894  C CE1 . TYR D 1 128 ? 115.545 104.192 79.377  1.00 78.46  ? 74  TYR D CE1 1 
ATOM   8895  C CE2 . TYR D 1 128 ? 115.298 106.283 80.504  1.00 74.10  ? 74  TYR D CE2 1 
ATOM   8896  C CZ  . TYR D 1 128 ? 115.483 104.919 80.543  1.00 74.25  ? 74  TYR D CZ  1 
ATOM   8897  O OH  . TYR D 1 128 ? 115.607 104.280 81.753  1.00 72.33  ? 74  TYR D OH  1 
ATOM   8898  N N   . SER D 1 129 ? 113.482 105.274 74.510  1.00 92.27  ? 75  SER D N   1 
ATOM   8899  C CA  . SER D 1 129 ? 113.081 104.011 73.913  1.00 94.55  ? 75  SER D CA  1 
ATOM   8900  C C   . SER D 1 129 ? 114.308 103.238 73.449  1.00 96.12  ? 75  SER D C   1 
ATOM   8901  O O   . SER D 1 129 ? 115.344 103.823 73.120  1.00 94.41  ? 75  SER D O   1 
ATOM   8902  C CB  . SER D 1 129 ? 112.132 104.232 72.729  1.00 98.32  ? 75  SER D CB  1 
ATOM   8903  O OG  . SER D 1 129 ? 112.760 104.986 71.707  1.00 100.97 ? 75  SER D OG  1 
ATOM   8904  N N   . GLY D 1 130 ? 114.177 101.912 73.429  1.00 95.98  ? 76  GLY D N   1 
ATOM   8905  C CA  . GLY D 1 130 ? 115.241 101.038 72.989  1.00 98.16  ? 76  GLY D CA  1 
ATOM   8906  C C   . GLY D 1 130 ? 116.269 100.686 74.040  1.00 100.45 ? 76  GLY D C   1 
ATOM   8907  O O   . GLY D 1 130 ? 117.154 99.867  73.764  1.00 105.69 ? 76  GLY D O   1 
ATOM   8908  N N   . ILE D 1 131 ? 116.189 101.267 75.229  1.00 96.76  ? 77  ILE D N   1 
ATOM   8909  C CA  . ILE D 1 131 ? 117.129 101.002 76.308  1.00 95.32  ? 77  ILE D CA  1 
ATOM   8910  C C   . ILE D 1 131 ? 116.352 100.447 77.494  1.00 95.84  ? 77  ILE D C   1 
ATOM   8911  O O   . ILE D 1 131 ? 115.679 101.189 78.211  1.00 95.37  ? 77  ILE D O   1 
ATOM   8912  C CB  . ILE D 1 131 ? 117.910 102.269 76.701  1.00 92.69  ? 77  ILE D CB  1 
ATOM   8913  C CG1 . ILE D 1 131 ? 118.578 102.882 75.470  1.00 90.81  ? 77  ILE D CG1 1 
ATOM   8914  C CG2 . ILE D 1 131 ? 118.948 101.944 77.763  1.00 91.67  ? 77  ILE D CG2 1 
ATOM   8915  C CD1 . ILE D 1 131 ? 119.347 104.148 75.761  1.00 88.89  ? 77  ILE D CD1 1 
ATOM   8916  N N   . PRO D 1 132 ? 116.420 99.133  77.736  1.00 95.25  ? 78  PRO D N   1 
ATOM   8917  C CA  . PRO D 1 132 ? 115.747 98.520  78.889  1.00 94.40  ? 78  PRO D CA  1 
ATOM   8918  C C   . PRO D 1 132 ? 116.537 98.657  80.190  1.00 90.31  ? 78  PRO D C   1 
ATOM   8919  O O   . PRO D 1 132 ? 116.714 97.693  80.936  1.00 89.56  ? 78  PRO D O   1 
ATOM   8920  C CB  . PRO D 1 132 ? 115.613 97.056  78.459  1.00 94.92  ? 78  PRO D CB  1 
ATOM   8921  C CG  . PRO D 1 132 ? 116.809 96.828  77.602  1.00 93.11  ? 78  PRO D CG  1 
ATOM   8922  C CD  . PRO D 1 132 ? 117.065 98.126  76.875  1.00 92.32  ? 78  PRO D CD  1 
ATOM   8923  N N   . LEU D 1 133 ? 117.011 99.870  80.464  1.00 88.29  ? 79  LEU D N   1 
ATOM   8924  C CA  . LEU D 1 133 ? 117.827 100.144 81.636  1.00 84.56  ? 79  LEU D CA  1 
ATOM   8925  C C   . LEU D 1 133 ? 117.353 101.429 82.294  1.00 83.07  ? 79  LEU D C   1 
ATOM   8926  O O   . LEU D 1 133 ? 116.772 102.301 81.644  1.00 83.15  ? 79  LEU D O   1 
ATOM   8927  C CB  . LEU D 1 133 ? 119.314 100.272 81.275  1.00 86.43  ? 79  LEU D CB  1 
ATOM   8928  C CG  . LEU D 1 133 ? 120.010 99.043  80.693  1.00 92.72  ? 79  LEU D CG  1 
ATOM   8929  C CD1 . LEU D 1 133 ? 121.444 99.378  80.316  1.00 99.07  ? 79  LEU D CD1 1 
ATOM   8930  C CD2 . LEU D 1 133 ? 119.968 97.894  81.684  1.00 88.32  ? 79  LEU D CD2 1 
ATOM   8931  N N   . ASN D 1 134 ? 117.605 101.535 83.596  1.00 78.15  ? 80  ASN D N   1 
ATOM   8932  C CA  . ASN D 1 134 ? 117.321 102.750 84.350  1.00 72.38  ? 80  ASN D CA  1 
ATOM   8933  C C   . ASN D 1 134 ? 118.586 103.598 84.381  1.00 72.32  ? 80  ASN D C   1 
ATOM   8934  O O   . ASN D 1 134 ? 119.575 103.228 85.021  1.00 73.86  ? 80  ASN D O   1 
ATOM   8935  C CB  . ASN D 1 134 ? 116.846 102.412 85.759  1.00 73.93  ? 80  ASN D CB  1 
ATOM   8936  C CG  . ASN D 1 134 ? 115.481 101.760 85.770  1.00 80.78  ? 80  ASN D CG  1 
ATOM   8937  O OD1 . ASN D 1 134 ? 114.736 101.832 84.794  1.00 80.11  ? 80  ASN D OD1 1 
ATOM   8938  N ND2 . ASN D 1 134 ? 115.144 101.122 86.881  1.00 87.00  ? 80  ASN D ND2 1 
ATOM   8939  N N   . LEU D 1 135 ? 118.556 104.735 83.692  1.00 67.98  ? 81  LEU D N   1 
ATOM   8940  C CA  . LEU D 1 135 ? 119.754 105.545 83.498  1.00 61.58  ? 81  LEU D CA  1 
ATOM   8941  C C   . LEU D 1 135 ? 120.035 106.346 84.762  1.00 62.14  ? 81  LEU D C   1 
ATOM   8942  O O   . LEU D 1 135 ? 119.305 107.287 85.082  1.00 64.58  ? 81  LEU D O   1 
ATOM   8943  C CB  . LEU D 1 135 ? 119.581 106.468 82.296  1.00 61.58  ? 81  LEU D CB  1 
ATOM   8944  C CG  . LEU D 1 135 ? 119.139 105.808 80.991  1.00 66.16  ? 81  LEU D CG  1 
ATOM   8945  C CD1 . LEU D 1 135 ? 119.034 106.842 79.884  1.00 64.44  ? 81  LEU D CD1 1 
ATOM   8946  C CD2 . LEU D 1 135 ? 120.097 104.699 80.602  1.00 71.27  ? 81  LEU D CD2 1 
ATOM   8947  N N   . THR D 1 136 ? 121.087 105.977 85.484  1.00 62.66  ? 82  THR D N   1 
ATOM   8948  C CA  . THR D 1 136 ? 121.544 106.749 86.634  1.00 61.88  ? 82  THR D CA  1 
ATOM   8949  C C   . THR D 1 136 ? 122.551 107.774 86.131  1.00 60.11  ? 82  THR D C   1 
ATOM   8950  O O   . THR D 1 136 ? 123.691 107.427 85.808  1.00 64.41  ? 82  THR D O   1 
ATOM   8951  C CB  . THR D 1 136 ? 122.158 105.840 87.694  1.00 64.88  ? 82  THR D CB  1 
ATOM   8952  O OG1 . THR D 1 136 ? 121.160 104.938 88.185  1.00 67.38  ? 82  THR D OG1 1 
ATOM   8953  C CG2 . THR D 1 136 ? 122.701 106.663 88.852  1.00 62.85  ? 82  THR D CG2 1 
ATOM   8954  N N   . LEU D 1 137 ? 122.134 109.032 86.058  1.00 57.17  ? 83  LEU D N   1 
ATOM   8955  C CA  . LEU D 1 137 ? 122.959 110.062 85.449  1.00 58.55  ? 83  LEU D CA  1 
ATOM   8956  C C   . LEU D 1 137 ? 123.776 110.797 86.502  1.00 62.21  ? 83  LEU D C   1 
ATOM   8957  O O   . LEU D 1 137 ? 123.485 110.748 87.699  1.00 64.24  ? 83  LEU D O   1 
ATOM   8958  C CB  . LEU D 1 137 ? 122.098 111.058 84.669  1.00 55.32  ? 83  LEU D CB  1 
ATOM   8959  C CG  . LEU D 1 137 ? 121.343 110.508 83.459  1.00 55.56  ? 83  LEU D CG  1 
ATOM   8960  C CD1 . LEU D 1 137 ? 120.658 111.637 82.710  1.00 53.87  ? 83  LEU D CD1 1 
ATOM   8961  C CD2 . LEU D 1 137 ? 122.283 109.747 82.542  1.00 57.66  ? 83  LEU D CD2 1 
ATOM   8962  N N   . ASP D 1 138 ? 124.819 111.477 86.033  1.00 57.67  ? 84  ASP D N   1 
ATOM   8963  C CA  . ASP D 1 138 ? 125.621 112.314 86.910  1.00 58.58  ? 84  ASP D CA  1 
ATOM   8964  C C   . ASP D 1 138 ? 124.758 113.421 87.501  1.00 61.36  ? 84  ASP D C   1 
ATOM   8965  O O   . ASP D 1 138 ? 123.878 113.967 86.832  1.00 67.97  ? 84  ASP D O   1 
ATOM   8966  C CB  . ASP D 1 138 ? 126.796 112.911 86.138  1.00 57.92  ? 84  ASP D CB  1 
ATOM   8967  C CG  . ASP D 1 138 ? 127.769 113.645 87.033  1.00 66.73  ? 84  ASP D CG  1 
ATOM   8968  O OD1 . ASP D 1 138 ? 127.694 113.470 88.267  1.00 68.20  ? 84  ASP D OD1 1 
ATOM   8969  O OD2 . ASP D 1 138 ? 128.610 114.400 86.504  1.00 71.97  ? 84  ASP D OD2 1 
ATOM   8970  N N   . ASN D 1 139 ? 125.016 113.753 88.769  1.00 58.90  ? 85  ASN D N   1 
ATOM   8971  C CA  . ASN D 1 139 ? 124.182 114.722 89.472  1.00 58.27  ? 85  ASN D CA  1 
ATOM   8972  C C   . ASN D 1 139 ? 124.184 116.091 88.806  1.00 60.51  ? 85  ASN D C   1 
ATOM   8973  O O   . ASN D 1 139 ? 123.231 116.857 88.988  1.00 64.95  ? 85  ASN D O   1 
ATOM   8974  C CB  . ASN D 1 139 ? 124.642 114.853 90.924  1.00 55.55  ? 85  ASN D CB  1 
ATOM   8975  C CG  . ASN D 1 139 ? 126.109 115.210 91.041  1.00 59.17  ? 85  ASN D CG  1 
ATOM   8976  O OD1 . ASN D 1 139 ? 126.480 116.383 91.008  1.00 59.95  ? 85  ASN D OD1 1 
ATOM   8977  N ND2 . ASN D 1 139 ? 126.953 114.196 91.184  1.00 61.09  ? 85  ASN D ND2 1 
ATOM   8978  N N   . ARG D 1 140 ? 125.224 116.414 88.035  1.00 59.42  ? 86  ARG D N   1 
ATOM   8979  C CA  . ARG D 1 140 ? 125.280 117.712 87.372  1.00 62.62  ? 86  ARG D CA  1 
ATOM   8980  C C   . ARG D 1 140 ? 124.130 117.895 86.390  1.00 64.00  ? 86  ARG D C   1 
ATOM   8981  O O   . ARG D 1 140 ? 123.687 119.027 86.160  1.00 65.28  ? 86  ARG D O   1 
ATOM   8982  C CB  . ARG D 1 140 ? 126.629 117.876 86.673  1.00 58.83  ? 86  ARG D CB  1 
ATOM   8983  C CG  . ARG D 1 140 ? 127.777 118.093 87.643  1.00 60.77  ? 86  ARG D CG  1 
ATOM   8984  C CD  . ARG D 1 140 ? 129.129 118.030 86.959  1.00 63.62  ? 86  ARG D CD  1 
ATOM   8985  N NE  . ARG D 1 140 ? 129.679 116.680 86.961  1.00 72.72  ? 86  ARG D NE  1 
ATOM   8986  C CZ  . ARG D 1 140 ? 130.954 116.393 86.737  1.00 79.62  ? 86  ARG D CZ  1 
ATOM   8987  N NH1 . ARG D 1 140 ? 131.841 117.342 86.487  1.00 86.07  ? 86  ARG D NH1 1 
ATOM   8988  N NH2 . ARG D 1 140 ? 131.349 115.124 86.771  1.00 81.81  ? 86  ARG D NH2 1 
ATOM   8989  N N   . VAL D 1 141 ? 123.617 116.800 85.822  1.00 62.63  ? 87  VAL D N   1 
ATOM   8990  C CA  . VAL D 1 141 ? 122.483 116.894 84.911  1.00 58.61  ? 87  VAL D CA  1 
ATOM   8991  C C   . VAL D 1 141 ? 121.251 117.442 85.612  1.00 61.58  ? 87  VAL D C   1 
ATOM   8992  O O   . VAL D 1 141 ? 120.312 117.892 84.949  1.00 65.89  ? 87  VAL D O   1 
ATOM   8993  C CB  . VAL D 1 141 ? 122.179 115.523 84.269  1.00 49.63  ? 87  VAL D CB  1 
ATOM   8994  C CG1 . VAL D 1 141 ? 121.302 114.686 85.184  1.00 51.85  ? 87  VAL D CG1 1 
ATOM   8995  C CG2 . VAL D 1 141 ? 121.514 115.710 82.919  1.00 54.27  ? 87  VAL D CG2 1 
ATOM   8996  N N   . ALA D 1 142 ? 121.228 117.418 86.948  1.00 59.30  ? 88  ALA D N   1 
ATOM   8997  C CA  . ALA D 1 142 ? 120.120 118.020 87.677  1.00 57.98  ? 88  ALA D CA  1 
ATOM   8998  C C   . ALA D 1 142 ? 120.013 119.515 87.417  1.00 65.20  ? 88  ALA D C   1 
ATOM   8999  O O   . ALA D 1 142 ? 118.952 120.101 87.657  1.00 67.74  ? 88  ALA D O   1 
ATOM   9000  C CB  . ALA D 1 142 ? 120.268 117.758 89.175  1.00 56.60  ? 88  ALA D CB  1 
ATOM   9001  N N   . ASP D 1 143 ? 121.085 120.144 86.932  1.00 72.04  ? 89  ASP D N   1 
ATOM   9002  C CA  . ASP D 1 143 ? 121.038 121.556 86.579  1.00 73.98  ? 89  ASP D CA  1 
ATOM   9003  C C   . ASP D 1 143 ? 120.374 121.804 85.232  1.00 68.50  ? 89  ASP D C   1 
ATOM   9004  O O   . ASP D 1 143 ? 120.158 122.965 84.870  1.00 69.67  ? 89  ASP D O   1 
ATOM   9005  C CB  . ASP D 1 143 ? 122.452 122.140 86.566  1.00 74.79  ? 89  ASP D CB  1 
ATOM   9006  C CG  . ASP D 1 143 ? 123.225 121.821 87.829  1.00 78.29  ? 89  ASP D CG  1 
ATOM   9007  O OD1 . ASP D 1 143 ? 122.598 121.735 88.906  1.00 75.80  ? 89  ASP D OD1 1 
ATOM   9008  O OD2 . ASP D 1 143 ? 124.460 121.652 87.745  1.00 78.95  ? 89  ASP D OD2 1 
ATOM   9009  N N   . GLN D 1 144 ? 120.048 120.747 84.486  1.00 64.69  ? 90  GLN D N   1 
ATOM   9010  C CA  . GLN D 1 144 ? 119.432 120.865 83.170  1.00 61.17  ? 90  GLN D CA  1 
ATOM   9011  C C   . GLN D 1 144 ? 118.043 120.239 83.137  1.00 63.01  ? 90  GLN D C   1 
ATOM   9012  O O   . GLN D 1 144 ? 117.517 119.963 82.055  1.00 64.84  ? 90  GLN D O   1 
ATOM   9013  C CB  . GLN D 1 144 ? 120.327 120.228 82.108  1.00 60.20  ? 90  GLN D CB  1 
ATOM   9014  C CG  . GLN D 1 144 ? 121.785 120.632 82.215  1.00 64.48  ? 90  GLN D CG  1 
ATOM   9015  C CD  . GLN D 1 144 ? 122.691 119.773 81.359  1.00 74.47  ? 90  GLN D CD  1 
ATOM   9016  O OE1 . GLN D 1 144 ? 122.273 119.240 80.333  1.00 81.54  ? 90  GLN D OE1 1 
ATOM   9017  N NE2 . GLN D 1 144 ? 123.941 119.629 81.784  1.00 69.99  ? 90  GLN D NE2 1 
ATOM   9018  N N   . LEU D 1 145 ? 117.441 120.007 84.300  1.00 62.76  ? 91  LEU D N   1 
ATOM   9019  C CA  . LEU D 1 145 ? 116.133 119.381 84.396  1.00 63.17  ? 91  LEU D CA  1 
ATOM   9020  C C   . LEU D 1 145 ? 115.215 120.235 85.258  1.00 63.44  ? 91  LEU D C   1 
ATOM   9021  O O   . LEU D 1 145 ? 115.665 121.064 86.052  1.00 61.26  ? 91  LEU D O   1 
ATOM   9022  C CB  . LEU D 1 145 ? 116.220 117.969 84.995  1.00 57.71  ? 91  LEU D CB  1 
ATOM   9023  C CG  . LEU D 1 145 ? 116.984 116.889 84.231  1.00 55.26  ? 91  LEU D CG  1 
ATOM   9024  C CD1 . LEU D 1 145 ? 117.064 115.623 85.067  1.00 44.32  ? 91  LEU D CD1 1 
ATOM   9025  C CD2 . LEU D 1 145 ? 116.316 116.605 82.900  1.00 55.43  ? 91  LEU D CD2 1 
ATOM   9026  N N   . TRP D 1 146 ? 113.914 120.024 85.085  1.00 61.77  ? 92  TRP D N   1 
ATOM   9027  C CA  . TRP D 1 146 ? 112.929 120.609 85.981  1.00 52.09  ? 92  TRP D CA  1 
ATOM   9028  C C   . TRP D 1 146 ? 112.822 119.756 87.236  1.00 52.05  ? 92  TRP D C   1 
ATOM   9029  O O   . TRP D 1 146 ? 112.719 118.529 87.155  1.00 55.57  ? 92  TRP D O   1 
ATOM   9030  C CB  . TRP D 1 146 ? 111.568 120.715 85.297  1.00 49.87  ? 92  TRP D CB  1 
ATOM   9031  C CG  . TRP D 1 146 ? 110.497 121.269 86.189  1.00 53.66  ? 92  TRP D CG  1 
ATOM   9032  C CD1 . TRP D 1 146 ? 110.105 122.570 86.286  1.00 55.58  ? 92  TRP D CD1 1 
ATOM   9033  C CD2 . TRP D 1 146 ? 109.683 120.535 87.114  1.00 53.36  ? 92  TRP D CD2 1 
ATOM   9034  N NE1 . TRP D 1 146 ? 109.098 122.694 87.211  1.00 53.87  ? 92  TRP D NE1 1 
ATOM   9035  C CE2 . TRP D 1 146 ? 108.821 121.459 87.734  1.00 51.59  ? 92  TRP D CE2 1 
ATOM   9036  C CE3 . TRP D 1 146 ? 109.602 119.188 87.478  1.00 51.71  ? 92  TRP D CE3 1 
ATOM   9037  C CZ2 . TRP D 1 146 ? 107.889 121.080 88.695  1.00 51.14  ? 92  TRP D CZ2 1 
ATOM   9038  C CZ3 . TRP D 1 146 ? 108.676 118.815 88.430  1.00 46.95  ? 92  TRP D CZ3 1 
ATOM   9039  C CH2 . TRP D 1 146 ? 107.832 119.756 89.029  1.00 47.73  ? 92  TRP D CH2 1 
ATOM   9040  N N   . VAL D 1 147 ? 112.843 120.405 88.394  1.00 52.40  ? 93  VAL D N   1 
ATOM   9041  C CA  . VAL D 1 147 ? 112.703 119.709 89.670  1.00 47.55  ? 93  VAL D CA  1 
ATOM   9042  C C   . VAL D 1 147 ? 111.645 120.434 90.491  1.00 48.16  ? 93  VAL D C   1 
ATOM   9043  O O   . VAL D 1 147 ? 111.480 121.653 90.343  1.00 50.38  ? 93  VAL D O   1 
ATOM   9044  C CB  . VAL D 1 147 ? 114.043 119.633 90.417  1.00 46.26  ? 93  VAL D CB  1 
ATOM   9045  C CG1 . VAL D 1 147 ? 115.012 118.731 89.672  1.00 44.54  ? 93  VAL D CG1 1 
ATOM   9046  C CG2 . VAL D 1 147 ? 114.633 121.021 90.578  1.00 52.34  ? 93  VAL D CG2 1 
ATOM   9047  N N   . PRO D 1 148 ? 110.902 119.739 91.351  1.00 46.26  ? 94  PRO D N   1 
ATOM   9048  C CA  . PRO D 1 148 ? 109.875 120.418 92.145  1.00 47.28  ? 94  PRO D CA  1 
ATOM   9049  C C   . PRO D 1 148 ? 110.487 121.457 93.071  1.00 48.79  ? 94  PRO D C   1 
ATOM   9050  O O   . PRO D 1 148 ? 111.624 121.325 93.528  1.00 52.16  ? 94  PRO D O   1 
ATOM   9051  C CB  . PRO D 1 148 ? 109.223 119.278 92.934  1.00 45.30  ? 94  PRO D CB  1 
ATOM   9052  C CG  . PRO D 1 148 ? 109.512 118.054 92.132  1.00 44.34  ? 94  PRO D CG  1 
ATOM   9053  C CD  . PRO D 1 148 ? 110.872 118.281 91.549  1.00 45.01  ? 94  PRO D CD  1 
ATOM   9054  N N   . ASP D 1 149 ? 109.714 122.507 93.341  1.00 45.25  ? 95  ASP D N   1 
ATOM   9055  C CA  . ASP D 1 149 ? 110.165 123.576 94.222  1.00 42.61  ? 95  ASP D CA  1 
ATOM   9056  C C   . ASP D 1 149 ? 109.875 123.217 95.672  1.00 43.00  ? 95  ASP D C   1 
ATOM   9057  O O   . ASP D 1 149 ? 109.243 123.987 96.401  1.00 44.10  ? 95  ASP D O   1 
ATOM   9058  C CB  . ASP D 1 149 ? 109.489 124.894 93.850  1.00 49.41  ? 95  ASP D CB  1 
ATOM   9059  C CG  . ASP D 1 149 ? 107.980 124.785 93.825  1.00 54.24  ? 95  ASP D CG  1 
ATOM   9060  O OD1 . ASP D 1 149 ? 107.467 123.654 93.686  1.00 53.74  ? 95  ASP D OD1 1 
ATOM   9061  O OD2 . ASP D 1 149 ? 107.305 125.827 93.944  1.00 54.80  ? 95  ASP D OD2 1 
ATOM   9062  N N   . THR D 1 150 ? 110.341 122.048 96.095  1.00 43.83  ? 96  THR D N   1 
ATOM   9063  C CA  . THR D 1 150 ? 110.084 121.576 97.446  1.00 39.35  ? 96  THR D CA  1 
ATOM   9064  C C   . THR D 1 150 ? 110.946 122.333 98.446  1.00 38.54  ? 96  THR D C   1 
ATOM   9065  O O   . THR D 1 150 ? 112.156 122.474 98.254  1.00 49.54  ? 96  THR D O   1 
ATOM   9066  C CB  . THR D 1 150 ? 110.365 120.080 97.533  1.00 42.56  ? 96  THR D CB  1 
ATOM   9067  O OG1 . THR D 1 150 ? 109.376 119.364 96.784  1.00 42.32  ? 96  THR D OG1 1 
ATOM   9068  C CG2 . THR D 1 150 ? 110.346 119.619 98.970  1.00 43.91  ? 96  THR D CG2 1 
ATOM   9069  N N   . TYR D 1 151 ? 110.324 122.815 99.520  1.00 35.67  ? 97  TYR D N   1 
ATOM   9070  C CA  . TYR D 1 151 ? 111.055 123.471 100.590 1.00 37.38  ? 97  TYR D CA  1 
ATOM   9071  C C   . TYR D 1 151 ? 110.442 123.083 101.926 1.00 39.19  ? 97  TYR D C   1 
ATOM   9072  O O   . TYR D 1 151 ? 109.257 122.748 102.015 1.00 42.21  ? 97  TYR D O   1 
ATOM   9073  C CB  . TYR D 1 151 ? 111.065 124.998 100.428 1.00 36.23  ? 97  TYR D CB  1 
ATOM   9074  C CG  . TYR D 1 151 ? 109.786 125.686 100.845 1.00 36.04  ? 97  TYR D CG  1 
ATOM   9075  C CD1 . TYR D 1 151 ? 108.649 125.615 100.058 1.00 38.84  ? 97  TYR D CD1 1 
ATOM   9076  C CD2 . TYR D 1 151 ? 109.724 126.421 102.017 1.00 38.31  ? 97  TYR D CD2 1 
ATOM   9077  C CE1 . TYR D 1 151 ? 107.482 126.243 100.435 1.00 40.05  ? 97  TYR D CE1 1 
ATOM   9078  C CE2 . TYR D 1 151 ? 108.561 127.054 102.401 1.00 41.12  ? 97  TYR D CE2 1 
ATOM   9079  C CZ  . TYR D 1 151 ? 107.443 126.962 101.605 1.00 41.86  ? 97  TYR D CZ  1 
ATOM   9080  O OH  . TYR D 1 151 ? 106.280 127.591 101.979 1.00 44.47  ? 97  TYR D OH  1 
ATOM   9081  N N   . PHE D 1 152 ? 111.267 123.133 102.967 1.00 37.02  ? 98  PHE D N   1 
ATOM   9082  C CA  . PHE D 1 152 ? 110.851 122.763 104.312 1.00 33.20  ? 98  PHE D CA  1 
ATOM   9083  C C   . PHE D 1 152 ? 110.370 124.009 105.041 1.00 38.33  ? 98  PHE D C   1 
ATOM   9084  O O   . PHE D 1 152 ? 111.142 124.949 105.254 1.00 41.30  ? 98  PHE D O   1 
ATOM   9085  C CB  . PHE D 1 152 ? 111.998 122.089 105.056 1.00 36.51  ? 98  PHE D CB  1 
ATOM   9086  C CG  . PHE D 1 152 ? 112.589 120.937 104.307 1.00 40.62  ? 98  PHE D CG  1 
ATOM   9087  C CD1 . PHE D 1 152 ? 111.770 120.016 103.680 1.00 37.96  ? 98  PHE D CD1 1 
ATOM   9088  C CD2 . PHE D 1 152 ? 113.958 120.790 104.201 1.00 44.40  ? 98  PHE D CD2 1 
ATOM   9089  C CE1 . PHE D 1 152 ? 112.304 118.960 102.979 1.00 36.91  ? 98  PHE D CE1 1 
ATOM   9090  C CE2 . PHE D 1 152 ? 114.498 119.736 103.501 1.00 41.82  ? 98  PHE D CE2 1 
ATOM   9091  C CZ  . PHE D 1 152 ? 113.669 118.821 102.887 1.00 40.57  ? 98  PHE D CZ  1 
ATOM   9092  N N   . LEU D 1 153 ? 109.093 124.009 105.421 1.00 41.53  ? 99  LEU D N   1 
ATOM   9093  C CA  . LEU D 1 153 ? 108.442 125.232 105.878 1.00 37.99  ? 99  LEU D CA  1 
ATOM   9094  C C   . LEU D 1 153 ? 109.067 125.770 107.161 1.00 39.15  ? 99  LEU D C   1 
ATOM   9095  O O   . LEU D 1 153 ? 109.285 126.980 107.289 1.00 47.61  ? 99  LEU D O   1 
ATOM   9096  C CB  . LEU D 1 153 ? 106.951 124.970 106.072 1.00 40.78  ? 99  LEU D CB  1 
ATOM   9097  C CG  . LEU D 1 153 ? 106.178 125.895 107.009 1.00 48.59  ? 99  LEU D CG  1 
ATOM   9098  C CD1 . LEU D 1 153 ? 106.094 127.293 106.435 1.00 53.13  ? 99  LEU D CD1 1 
ATOM   9099  C CD2 . LEU D 1 153 ? 104.793 125.335 107.262 1.00 57.70  ? 99  LEU D CD2 1 
ATOM   9100  N N   . ASN D 1 154 ? 109.371 124.896 108.115 1.00 38.48  ? 100 ASN D N   1 
ATOM   9101  C CA  . ASN D 1 154 ? 109.775 125.309 109.455 1.00 39.41  ? 100 ASN D CA  1 
ATOM   9102  C C   . ASN D 1 154 ? 111.258 125.067 109.718 1.00 43.33  ? 100 ASN D C   1 
ATOM   9103  O O   . ASN D 1 154 ? 111.653 124.704 110.827 1.00 49.06  ? 100 ASN D O   1 
ATOM   9104  C CB  . ASN D 1 154 ? 108.936 124.599 110.512 1.00 46.55  ? 100 ASN D CB  1 
ATOM   9105  C CG  . ASN D 1 154 ? 109.071 123.094 110.446 1.00 46.41  ? 100 ASN D CG  1 
ATOM   9106  O OD1 . ASN D 1 154 ? 109.137 122.513 109.363 1.00 43.26  ? 100 ASN D OD1 1 
ATOM   9107  N ND2 . ASN D 1 154 ? 109.116 122.453 111.606 1.00 48.16  ? 100 ASN D ND2 1 
ATOM   9108  N N   . ASP D 1 155 ? 112.097 125.262 108.709 1.00 44.76  ? 101 ASP D N   1 
ATOM   9109  C CA  . ASP D 1 155 ? 113.537 125.145 108.881 1.00 41.93  ? 101 ASP D CA  1 
ATOM   9110  C C   . ASP D 1 155 ? 114.153 126.520 109.114 1.00 41.19  ? 101 ASP D C   1 
ATOM   9111  O O   . ASP D 1 155 ? 113.528 127.558 108.886 1.00 45.69  ? 101 ASP D O   1 
ATOM   9112  C CB  . ASP D 1 155 ? 114.177 124.464 107.668 1.00 47.36  ? 101 ASP D CB  1 
ATOM   9113  C CG  . ASP D 1 155 ? 114.248 125.370 106.457 1.00 53.40  ? 101 ASP D CG  1 
ATOM   9114  O OD1 . ASP D 1 155 ? 113.354 126.226 106.293 1.00 58.12  ? 101 ASP D OD1 1 
ATOM   9115  O OD2 . ASP D 1 155 ? 115.202 125.229 105.664 1.00 55.05  ? 101 ASP D OD2 1 
ATOM   9116  N N   . LYS D 1 156 ? 115.398 126.515 109.572 1.00 40.27  ? 102 LYS D N   1 
ATOM   9117  C CA  . LYS D 1 156 ? 116.130 127.742 109.850 1.00 43.05  ? 102 LYS D CA  1 
ATOM   9118  C C   . LYS D 1 156 ? 117.450 127.824 109.108 1.00 47.79  ? 102 LYS D C   1 
ATOM   9119  O O   . LYS D 1 156 ? 117.828 128.904 108.648 1.00 57.42  ? 102 LYS D O   1 
ATOM   9120  C CB  . LYS D 1 156 ? 116.377 127.867 111.358 1.00 46.45  ? 102 LYS D CB  1 
ATOM   9121  C CG  . LYS D 1 156 ? 115.118 127.711 112.188 1.00 47.06  ? 102 LYS D CG  1 
ATOM   9122  C CD  . LYS D 1 156 ? 115.421 127.623 113.669 1.00 45.31  ? 102 LYS D CD  1 
ATOM   9123  C CE  . LYS D 1 156 ? 116.001 128.921 114.195 1.00 51.81  ? 102 LYS D CE  1 
ATOM   9124  N NZ  . LYS D 1 156 ? 116.229 128.854 115.663 1.00 57.51  ? 102 LYS D NZ  1 
ATOM   9125  N N   . LYS D 1 157 ? 118.163 126.707 108.978 1.00 45.74  ? 103 LYS D N   1 
ATOM   9126  C CA  . LYS D 1 157 ? 119.389 126.662 108.186 1.00 53.63  ? 103 LYS D CA  1 
ATOM   9127  C C   . LYS D 1 157 ? 119.559 125.225 107.704 1.00 56.14  ? 103 LYS D C   1 
ATOM   9128  O O   . LYS D 1 157 ? 119.983 124.357 108.472 1.00 61.57  ? 103 LYS D O   1 
ATOM   9129  C CB  . LYS D 1 157 ? 120.593 127.128 108.993 1.00 54.56  ? 103 LYS D CB  1 
ATOM   9130  C CG  . LYS D 1 157 ? 121.200 128.425 108.499 1.00 55.60  ? 103 LYS D CG  1 
ATOM   9131  C CD  . LYS D 1 157 ? 121.661 128.308 107.057 1.00 56.88  ? 103 LYS D CD  1 
ATOM   9132  C CE  . LYS D 1 157 ? 122.263 129.614 106.571 1.00 58.23  ? 103 LYS D CE  1 
ATOM   9133  N NZ  . LYS D 1 157 ? 122.740 129.527 105.164 1.00 55.33  ? 103 LYS D NZ  1 
ATOM   9134  N N   . SER D 1 158 ? 119.222 124.985 106.442 1.00 50.58  ? 104 SER D N   1 
ATOM   9135  C CA  . SER D 1 158 ? 119.343 123.672 105.827 1.00 48.35  ? 104 SER D CA  1 
ATOM   9136  C C   . SER D 1 158 ? 120.291 123.753 104.641 1.00 44.66  ? 104 SER D C   1 
ATOM   9137  O O   . SER D 1 158 ? 120.291 124.740 103.901 1.00 52.77  ? 104 SER D O   1 
ATOM   9138  C CB  . SER D 1 158 ? 117.977 123.146 105.382 1.00 48.81  ? 104 SER D CB  1 
ATOM   9139  O OG  . SER D 1 158 ? 117.253 124.143 104.684 1.00 62.92  ? 104 SER D OG  1 
ATOM   9140  N N   . PHE D 1 159 ? 121.105 122.714 104.467 1.00 39.92  ? 105 PHE D N   1 
ATOM   9141  C CA  . PHE D 1 159 ? 122.060 122.661 103.372 1.00 40.43  ? 105 PHE D CA  1 
ATOM   9142  C C   . PHE D 1 159 ? 122.093 121.253 102.798 1.00 41.96  ? 105 PHE D C   1 
ATOM   9143  O O   . PHE D 1 159 ? 121.523 120.313 103.358 1.00 46.17  ? 105 PHE D O   1 
ATOM   9144  C CB  . PHE D 1 159 ? 123.462 123.097 103.822 1.00 39.97  ? 105 PHE D CB  1 
ATOM   9145  C CG  . PHE D 1 159 ? 124.091 122.181 104.832 1.00 41.05  ? 105 PHE D CG  1 
ATOM   9146  C CD1 . PHE D 1 159 ? 123.867 122.360 106.185 1.00 45.50  ? 105 PHE D CD1 1 
ATOM   9147  C CD2 . PHE D 1 159 ? 124.920 121.148 104.428 1.00 40.54  ? 105 PHE D CD2 1 
ATOM   9148  C CE1 . PHE D 1 159 ? 124.448 121.522 107.114 1.00 45.22  ? 105 PHE D CE1 1 
ATOM   9149  C CE2 . PHE D 1 159 ? 125.503 120.305 105.353 1.00 39.23  ? 105 PHE D CE2 1 
ATOM   9150  C CZ  . PHE D 1 159 ? 125.268 120.494 106.697 1.00 38.50  ? 105 PHE D CZ  1 
ATOM   9151  N N   . VAL D 1 160 ? 122.768 121.119 101.661 1.00 39.11  ? 106 VAL D N   1 
ATOM   9152  C CA  . VAL D 1 160 ? 122.983 119.838 101.001 1.00 39.09  ? 106 VAL D CA  1 
ATOM   9153  C C   . VAL D 1 160 ? 124.475 119.544 101.022 1.00 44.37  ? 106 VAL D C   1 
ATOM   9154  O O   . VAL D 1 160 ? 125.283 120.381 100.603 1.00 51.13  ? 106 VAL D O   1 
ATOM   9155  C CB  . VAL D 1 160 ? 122.445 119.846 99.560  1.00 35.10  ? 106 VAL D CB  1 
ATOM   9156  C CG1 . VAL D 1 160 ? 122.693 118.504 98.898  1.00 36.69  ? 106 VAL D CG1 1 
ATOM   9157  C CG2 . VAL D 1 160 ? 120.967 120.184 99.549  1.00 35.72  ? 106 VAL D CG2 1 
ATOM   9158  N N   . HIS D 1 161 ? 124.838 118.361 101.513 1.00 36.38  ? 107 HIS D N   1 
ATOM   9159  C CA  . HIS D 1 161 ? 126.244 117.998 101.619 1.00 40.85  ? 107 HIS D CA  1 
ATOM   9160  C C   . HIS D 1 161 ? 126.891 117.961 100.240 1.00 45.69  ? 107 HIS D C   1 
ATOM   9161  O O   . HIS D 1 161 ? 126.271 117.554 99.256  1.00 48.13  ? 107 HIS D O   1 
ATOM   9162  C CB  . HIS D 1 161 ? 126.386 116.648 102.316 1.00 38.46  ? 107 HIS D CB  1 
ATOM   9163  C CG  . HIS D 1 161 ? 125.767 116.604 103.679 1.00 37.73  ? 107 HIS D CG  1 
ATOM   9164  N ND1 . HIS D 1 161 ? 126.516 116.587 104.835 1.00 40.24  ? 107 HIS D ND1 1 
ATOM   9165  C CD2 . HIS D 1 161 ? 124.472 116.585 104.070 1.00 39.85  ? 107 HIS D CD2 1 
ATOM   9166  C CE1 . HIS D 1 161 ? 125.708 116.552 105.880 1.00 39.24  ? 107 HIS D CE1 1 
ATOM   9167  N NE2 . HIS D 1 161 ? 124.462 116.552 105.443 1.00 39.44  ? 107 HIS D NE2 1 
ATOM   9168  N N   . GLY D 1 162 ? 128.147 118.399 100.172 1.00 41.97  ? 108 GLY D N   1 
ATOM   9169  C CA  . GLY D 1 162 ? 128.815 118.545 98.896  1.00 45.95  ? 108 GLY D CA  1 
ATOM   9170  C C   . GLY D 1 162 ? 130.206 117.951 98.821  1.00 49.13  ? 108 GLY D C   1 
ATOM   9171  O O   . GLY D 1 162 ? 131.086 118.512 98.163  1.00 54.65  ? 108 GLY D O   1 
ATOM   9172  N N   . VAL D 1 163 ? 130.425 116.823 99.492  1.00 43.42  ? 109 VAL D N   1 
ATOM   9173  C CA  . VAL D 1 163 ? 131.701 116.117 99.465  1.00 40.10  ? 109 VAL D CA  1 
ATOM   9174  C C   . VAL D 1 163 ? 131.420 114.638 99.239  1.00 42.56  ? 109 VAL D C   1 
ATOM   9175  O O   . VAL D 1 163 ? 130.608 114.046 99.957  1.00 46.94  ? 109 VAL D O   1 
ATOM   9176  C CB  . VAL D 1 163 ? 132.498 116.334 100.766 1.00 38.12  ? 109 VAL D CB  1 
ATOM   9177  C CG1 . VAL D 1 163 ? 133.730 115.453 100.796 1.00 40.03  ? 109 VAL D CG1 1 
ATOM   9178  C CG2 . VAL D 1 163 ? 132.892 117.790 100.903 1.00 41.92  ? 109 VAL D CG2 1 
ATOM   9179  N N   . THR D 1 164 ? 132.085 114.040 98.250  1.00 39.72  ? 110 THR D N   1 
ATOM   9180  C CA  . THR D 1 164 ? 133.081 114.712 97.415  1.00 44.48  ? 110 THR D CA  1 
ATOM   9181  C C   . THR D 1 164 ? 132.436 115.473 96.268  1.00 48.92  ? 110 THR D C   1 
ATOM   9182  O O   . THR D 1 164 ? 133.083 116.263 95.583  1.00 53.74  ? 110 THR D O   1 
ATOM   9183  C CB  . THR D 1 164 ? 134.083 113.706 96.832  1.00 43.37  ? 110 THR D CB  1 
ATOM   9184  O OG1 . THR D 1 164 ? 133.404 112.822 95.934  1.00 45.16  ? 110 THR D OG1 1 
ATOM   9185  C CG2 . THR D 1 164 ? 134.722 112.891 97.942  1.00 41.43  ? 110 THR D CG2 1 
ATOM   9186  N N   . VAL D 1 165 ? 131.150 115.216 96.062  1.00 43.78  ? 111 VAL D N   1 
ATOM   9187  C CA  . VAL D 1 165 ? 130.321 115.943 95.121  1.00 45.16  ? 111 VAL D CA  1 
ATOM   9188  C C   . VAL D 1 165 ? 129.035 116.324 95.843  1.00 47.12  ? 111 VAL D C   1 
ATOM   9189  O O   . VAL D 1 165 ? 128.814 115.939 96.989  1.00 50.31  ? 111 VAL D O   1 
ATOM   9190  C CB  . VAL D 1 165 ? 130.020 115.125 93.849  1.00 45.29  ? 111 VAL D CB  1 
ATOM   9191  C CG1 . VAL D 1 165 ? 131.309 114.675 93.180  1.00 43.78  ? 111 VAL D CG1 1 
ATOM   9192  C CG2 . VAL D 1 165 ? 129.143 113.934 94.191  1.00 41.19  ? 111 VAL D CG2 1 
ATOM   9193  N N   . LYS D 1 166 ? 128.188 117.091 95.166  1.00 49.13  ? 112 LYS D N   1 
ATOM   9194  C CA  . LYS D 1 166 ? 126.875 117.376 95.723  1.00 49.34  ? 112 LYS D CA  1 
ATOM   9195  C C   . LYS D 1 166 ? 126.124 116.068 95.918  1.00 50.78  ? 112 LYS D C   1 
ATOM   9196  O O   . LYS D 1 166 ? 125.933 115.309 94.965  1.00 53.87  ? 112 LYS D O   1 
ATOM   9197  C CB  . LYS D 1 166 ? 126.093 118.315 94.806  1.00 53.96  ? 112 LYS D CB  1 
ATOM   9198  C CG  . LYS D 1 166 ? 126.808 119.614 94.485  1.00 61.29  ? 112 LYS D CG  1 
ATOM   9199  C CD  . LYS D 1 166 ? 125.834 120.776 94.444  1.00 66.88  ? 112 LYS D CD  1 
ATOM   9200  C CE  . LYS D 1 166 ? 125.315 121.097 95.836  1.00 70.30  ? 112 LYS D CE  1 
ATOM   9201  N NZ  . LYS D 1 166 ? 126.425 121.481 96.750  1.00 68.68  ? 112 LYS D NZ  1 
ATOM   9202  N N   . ASN D 1 167 ? 125.706 115.799 97.153  1.00 47.82  ? 113 ASN D N   1 
ATOM   9203  C CA  . ASN D 1 167 ? 125.049 114.533 97.437  1.00 45.50  ? 113 ASN D CA  1 
ATOM   9204  C C   . ASN D 1 167 ? 123.682 114.537 96.775  1.00 46.12  ? 113 ASN D C   1 
ATOM   9205  O O   . ASN D 1 167 ? 122.675 114.894 97.393  1.00 45.76  ? 113 ASN D O   1 
ATOM   9206  C CB  . ASN D 1 167 ? 124.939 114.292 98.942  1.00 38.36  ? 113 ASN D CB  1 
ATOM   9207  C CG  . ASN D 1 167 ? 126.286 114.043 99.591  1.00 38.37  ? 113 ASN D CG  1 
ATOM   9208  O OD1 . ASN D 1 167 ? 126.387 113.927 100.809 1.00 42.24  ? 113 ASN D OD1 1 
ATOM   9209  N ND2 . ASN D 1 167 ? 127.330 113.962 98.775  1.00 39.96  ? 113 ASN D ND2 1 
ATOM   9210  N N   . ARG D 1 168 ? 123.652 114.136 95.509  1.00 45.30  ? 114 ARG D N   1 
ATOM   9211  C CA  . ARG D 1 168 ? 122.493 114.331 94.658  1.00 44.09  ? 114 ARG D CA  1 
ATOM   9212  C C   . ARG D 1 168 ? 122.440 113.199 93.646  1.00 48.94  ? 114 ARG D C   1 
ATOM   9213  O O   . ARG D 1 168 ? 123.466 112.820 93.076  1.00 55.88  ? 114 ARG D O   1 
ATOM   9214  C CB  . ARG D 1 168 ? 122.566 115.692 93.960  1.00 44.37  ? 114 ARG D CB  1 
ATOM   9215  C CG  . ARG D 1 168 ? 121.376 116.032 93.096  1.00 48.06  ? 114 ARG D CG  1 
ATOM   9216  C CD  . ARG D 1 168 ? 121.422 117.494 92.700  1.00 51.44  ? 114 ARG D CD  1 
ATOM   9217  N NE  . ARG D 1 168 ? 122.683 117.838 92.055  1.00 64.06  ? 114 ARG D NE  1 
ATOM   9218  C CZ  . ARG D 1 168 ? 123.026 119.064 91.686  1.00 65.87  ? 114 ARG D CZ  1 
ATOM   9219  N NH1 . ARG D 1 168 ? 122.224 120.097 91.891  1.00 60.99  ? 114 ARG D NH1 1 
ATOM   9220  N NH2 . ARG D 1 168 ? 124.203 119.260 91.099  1.00 65.82  ? 114 ARG D NH2 1 
ATOM   9221  N N   . MET D 1 169 ? 121.246 112.657 93.439  1.00 41.60  ? 115 MET D N   1 
ATOM   9222  C CA  . MET D 1 169 ? 121.057 111.499 92.578  1.00 41.15  ? 115 MET D CA  1 
ATOM   9223  C C   . MET D 1 169 ? 119.921 111.761 91.606  1.00 47.96  ? 115 MET D C   1 
ATOM   9224  O O   . MET D 1 169 ? 118.820 112.131 92.023  1.00 49.21  ? 115 MET D O   1 
ATOM   9225  C CB  . MET D 1 169 ? 120.758 110.245 93.399  1.00 39.67  ? 115 MET D CB  1 
ATOM   9226  C CG  . MET D 1 169 ? 120.310 109.062 92.564  1.00 45.81  ? 115 MET D CG  1 
ATOM   9227  S SD  . MET D 1 169 ? 119.811 107.659 93.573  1.00 71.67  ? 115 MET D SD  1 
ATOM   9228  C CE  . MET D 1 169 ? 118.468 108.385 94.503  1.00 55.55  ? 115 MET D CE  1 
ATOM   9229  N N   . ILE D 1 170 ? 120.189 111.556 90.319  1.00 50.26  ? 116 ILE D N   1 
ATOM   9230  C CA  . ILE D 1 170 ? 119.181 111.637 89.270  1.00 47.66  ? 116 ILE D CA  1 
ATOM   9231  C C   . ILE D 1 170 ? 119.107 110.278 88.592  1.00 51.60  ? 116 ILE D C   1 
ATOM   9232  O O   . ILE D 1 170 ? 120.116 109.776 88.076  1.00 59.75  ? 116 ILE D O   1 
ATOM   9233  C CB  . ILE D 1 170 ? 119.498 112.745 88.253  1.00 46.88  ? 116 ILE D CB  1 
ATOM   9234  C CG1 . ILE D 1 170 ? 119.046 114.103 88.788  1.00 46.85  ? 116 ILE D CG1 1 
ATOM   9235  C CG2 . ILE D 1 170 ? 118.822 112.460 86.923  1.00 49.97  ? 116 ILE D CG2 1 
ATOM   9236  C CD1 . ILE D 1 170 ? 117.547 114.291 88.758  1.00 44.27  ? 116 ILE D CD1 1 
ATOM   9237  N N   . ARG D 1 171 ? 117.919 109.678 88.601  1.00 46.66  ? 117 ARG D N   1 
ATOM   9238  C CA  . ARG D 1 171 ? 117.698 108.392 87.957  1.00 49.44  ? 117 ARG D CA  1 
ATOM   9239  C C   . ARG D 1 171 ? 116.481 108.498 87.054  1.00 50.85  ? 117 ARG D C   1 
ATOM   9240  O O   . ARG D 1 171 ? 115.417 108.947 87.491  1.00 55.75  ? 117 ARG D O   1 
ATOM   9241  C CB  . ARG D 1 171 ? 117.511 107.281 88.991  1.00 52.04  ? 117 ARG D CB  1 
ATOM   9242  C CG  . ARG D 1 171 ? 117.640 105.881 88.422  1.00 59.80  ? 117 ARG D CG  1 
ATOM   9243  C CD  . ARG D 1 171 ? 117.635 104.839 89.524  1.00 59.37  ? 117 ARG D CD  1 
ATOM   9244  N NE  . ARG D 1 171 ? 118.787 104.977 90.408  1.00 64.38  ? 117 ARG D NE  1 
ATOM   9245  C CZ  . ARG D 1 171 ? 119.017 104.207 91.463  1.00 67.60  ? 117 ARG D CZ  1 
ATOM   9246  N NH1 . ARG D 1 171 ? 118.184 103.238 91.805  1.00 72.81  ? 117 ARG D NH1 1 
ATOM   9247  N NH2 . ARG D 1 171 ? 120.110 104.414 92.191  1.00 63.73  ? 117 ARG D NH2 1 
ATOM   9248  N N   . LEU D 1 172 ? 116.641 108.088 85.800  1.00 52.29  ? 118 LEU D N   1 
ATOM   9249  C CA  . LEU D 1 172 ? 115.595 108.167 84.794  1.00 55.85  ? 118 LEU D CA  1 
ATOM   9250  C C   . LEU D 1 172 ? 115.112 106.770 84.438  1.00 62.76  ? 118 LEU D C   1 
ATOM   9251  O O   . LEU D 1 172 ? 115.911 105.836 84.310  1.00 68.64  ? 118 LEU D O   1 
ATOM   9252  C CB  . LEU D 1 172 ? 116.091 108.874 83.531  1.00 55.22  ? 118 LEU D CB  1 
ATOM   9253  C CG  . LEU D 1 172 ? 116.668 110.280 83.683  1.00 49.31  ? 118 LEU D CG  1 
ATOM   9254  C CD1 . LEU D 1 172 ? 117.041 110.843 82.324  1.00 49.79  ? 118 LEU D CD1 1 
ATOM   9255  C CD2 . LEU D 1 172 ? 115.678 111.189 84.382  1.00 49.66  ? 118 LEU D CD2 1 
ATOM   9256  N N   . HIS D 1 173 ? 113.805 106.643 84.268  1.00 65.19  ? 119 HIS D N   1 
ATOM   9257  C CA  . HIS D 1 173 ? 113.134 105.397 83.949  1.00 68.37  ? 119 HIS D CA  1 
ATOM   9258  C C   . HIS D 1 173 ? 112.549 105.458 82.543  1.00 71.94  ? 119 HIS D C   1 
ATOM   9259  O O   . HIS D 1 173 ? 112.304 106.545 82.010  1.00 75.35  ? 119 HIS D O   1 
ATOM   9260  C CB  . HIS D 1 173 ? 112.024 105.115 84.971  1.00 68.29  ? 119 HIS D CB  1 
ATOM   9261  C CG  . HIS D 1 173 ? 112.531 104.864 86.357  1.00 70.27  ? 119 HIS D CG  1 
ATOM   9262  N ND1 . HIS D 1 173 ? 113.468 105.671 86.966  1.00 64.45  ? 119 HIS D ND1 1 
ATOM   9263  C CD2 . HIS D 1 173 ? 112.232 103.895 87.253  1.00 72.17  ? 119 HIS D CD2 1 
ATOM   9264  C CE1 . HIS D 1 173 ? 113.725 105.210 88.176  1.00 67.65  ? 119 HIS D CE1 1 
ATOM   9265  N NE2 . HIS D 1 173 ? 112.987 104.133 88.376  1.00 72.28  ? 119 HIS D NE2 1 
ATOM   9266  N N   . PRO D 1 174 ? 112.330 104.305 81.903  1.00 71.44  ? 120 PRO D N   1 
ATOM   9267  C CA  . PRO D 1 174 ? 111.879 104.326 80.499  1.00 73.25  ? 120 PRO D CA  1 
ATOM   9268  C C   . PRO D 1 174 ? 110.582 105.083 80.269  1.00 74.77  ? 120 PRO D C   1 
ATOM   9269  O O   . PRO D 1 174 ? 110.425 105.720 79.220  1.00 74.13  ? 120 PRO D O   1 
ATOM   9270  C CB  . PRO D 1 174 ? 111.731 102.836 80.164  1.00 73.87  ? 120 PRO D CB  1 
ATOM   9271  C CG  . PRO D 1 174 ? 112.675 102.153 81.088  1.00 71.55  ? 120 PRO D CG  1 
ATOM   9272  C CD  . PRO D 1 174 ? 112.634 102.939 82.363  1.00 72.20  ? 120 PRO D CD  1 
ATOM   9273  N N   . ASP D 1 175 ? 109.644 105.038 81.215  1.00 72.86  ? 121 ASP D N   1 
ATOM   9274  C CA  . ASP D 1 175 ? 108.352 105.690 81.042  1.00 72.93  ? 121 ASP D CA  1 
ATOM   9275  C C   . ASP D 1 175 ? 108.370 107.164 81.430  1.00 75.70  ? 121 ASP D C   1 
ATOM   9276  O O   . ASP D 1 175 ? 107.305 107.735 81.695  1.00 77.55  ? 121 ASP D O   1 
ATOM   9277  C CB  . ASP D 1 175 ? 107.276 104.954 81.845  1.00 74.40  ? 121 ASP D CB  1 
ATOM   9278  C CG  . ASP D 1 175 ? 107.471 105.085 83.341  1.00 80.28  ? 121 ASP D CG  1 
ATOM   9279  O OD1 . ASP D 1 175 ? 108.635 105.106 83.792  1.00 76.55  ? 121 ASP D OD1 1 
ATOM   9280  O OD2 . ASP D 1 175 ? 106.459 105.171 84.068  1.00 86.33  ? 121 ASP D OD2 1 
ATOM   9281  N N   . GLY D 1 176 ? 109.542 107.793 81.469  1.00 75.42  ? 122 GLY D N   1 
ATOM   9282  C CA  . GLY D 1 176 ? 109.647 109.192 81.816  1.00 70.78  ? 122 GLY D CA  1 
ATOM   9283  C C   . GLY D 1 176 ? 109.766 109.479 83.295  1.00 63.84  ? 122 GLY D C   1 
ATOM   9284  O O   . GLY D 1 176 ? 109.906 110.650 83.672  1.00 63.69  ? 122 GLY D O   1 
ATOM   9285  N N   . THR D 1 177 ? 109.711 108.457 84.141  1.00 61.32  ? 123 THR D N   1 
ATOM   9286  C CA  . THR D 1 177 ? 109.763 108.665 85.580  1.00 58.16  ? 123 THR D CA  1 
ATOM   9287  C C   . THR D 1 177 ? 111.144 109.144 86.011  1.00 57.28  ? 123 THR D C   1 
ATOM   9288  O O   . THR D 1 177 ? 112.168 108.685 85.499  1.00 64.17  ? 123 THR D O   1 
ATOM   9289  C CB  . THR D 1 177 ? 109.402 107.374 86.308  1.00 61.08  ? 123 THR D CB  1 
ATOM   9290  O OG1 . THR D 1 177 ? 108.153 106.881 85.811  1.00 69.60  ? 123 THR D OG1 1 
ATOM   9291  C CG2 . THR D 1 177 ? 109.277 107.623 87.792  1.00 55.82  ? 123 THR D CG2 1 
ATOM   9292  N N   . VAL D 1 178 ? 111.165 110.077 86.957  1.00 50.04  ? 124 VAL D N   1 
ATOM   9293  C CA  . VAL D 1 178 ? 112.391 110.639 87.504  1.00 42.63  ? 124 VAL D CA  1 
ATOM   9294  C C   . VAL D 1 178 ? 112.402 110.408 89.007  1.00 46.52  ? 124 VAL D C   1 
ATOM   9295  O O   . VAL D 1 178 ? 111.408 110.688 89.695  1.00 57.36  ? 124 VAL D O   1 
ATOM   9296  C CB  . VAL D 1 178 ? 112.521 112.139 87.186  1.00 37.66  ? 124 VAL D CB  1 
ATOM   9297  C CG1 . VAL D 1 178 ? 113.831 112.683 87.732  1.00 37.47  ? 124 VAL D CG1 1 
ATOM   9298  C CG2 . VAL D 1 178 ? 112.423 112.373 85.694  1.00 44.82  ? 124 VAL D CG2 1 
ATOM   9299  N N   . LEU D 1 179 ? 113.521 109.887 89.504  1.00 43.32  ? 125 LEU D N   1 
ATOM   9300  C CA  . LEU D 1 179 ? 113.825 109.834 90.925  1.00 41.90  ? 125 LEU D CA  1 
ATOM   9301  C C   . LEU D 1 179 ? 114.956 110.811 91.205  1.00 42.44  ? 125 LEU D C   1 
ATOM   9302  O O   . LEU D 1 179 ? 116.012 110.748 90.565  1.00 47.00  ? 125 LEU D O   1 
ATOM   9303  C CB  . LEU D 1 179 ? 114.217 108.419 91.358  1.00 46.67  ? 125 LEU D CB  1 
ATOM   9304  C CG  . LEU D 1 179 ? 115.067 108.266 92.624  1.00 42.70  ? 125 LEU D CG  1 
ATOM   9305  C CD1 . LEU D 1 179 ? 114.368 108.835 93.846  1.00 42.66  ? 125 LEU D CD1 1 
ATOM   9306  C CD2 . LEU D 1 179 ? 115.417 106.805 92.847  1.00 47.52  ? 125 LEU D CD2 1 
ATOM   9307  N N   . TYR D 1 180 ? 114.728 111.712 92.158  1.00 37.43  ? 126 TYR D N   1 
ATOM   9308  C CA  . TYR D 1 180 ? 115.654 112.795 92.468  1.00 36.71  ? 126 TYR D CA  1 
ATOM   9309  C C   . TYR D 1 180 ? 115.907 112.781 93.967  1.00 40.74  ? 126 TYR D C   1 
ATOM   9310  O O   . TYR D 1 180 ? 115.003 113.073 94.754  1.00 45.61  ? 126 TYR D O   1 
ATOM   9311  C CB  . TYR D 1 180 ? 115.081 114.135 92.009  1.00 37.31  ? 126 TYR D CB  1 
ATOM   9312  C CG  . TYR D 1 180 ? 115.901 115.344 92.371  1.00 38.37  ? 126 TYR D CG  1 
ATOM   9313  C CD1 . TYR D 1 180 ? 117.247 115.413 92.061  1.00 39.50  ? 126 TYR D CD1 1 
ATOM   9314  C CD2 . TYR D 1 180 ? 115.317 116.436 92.994  1.00 41.75  ? 126 TYR D CD2 1 
ATOM   9315  C CE1 . TYR D 1 180 ? 117.993 116.523 92.380  1.00 41.34  ? 126 TYR D CE1 1 
ATOM   9316  C CE2 . TYR D 1 180 ? 116.055 117.549 93.316  1.00 41.06  ? 126 TYR D CE2 1 
ATOM   9317  C CZ  . TYR D 1 180 ? 117.392 117.588 93.006  1.00 42.18  ? 126 TYR D CZ  1 
ATOM   9318  O OH  . TYR D 1 180 ? 118.135 118.698 93.326  1.00 46.62  ? 126 TYR D OH  1 
ATOM   9319  N N   . GLY D 1 181 ? 117.122 112.440 94.361  1.00 40.46  ? 127 GLY D N   1 
ATOM   9320  C CA  . GLY D 1 181 ? 117.457 112.250 95.764  1.00 39.02  ? 127 GLY D CA  1 
ATOM   9321  C C   . GLY D 1 181 ? 118.496 113.249 96.229  1.00 39.34  ? 127 GLY D C   1 
ATOM   9322  O O   . GLY D 1 181 ? 119.434 113.563 95.498  1.00 45.41  ? 127 GLY D O   1 
ATOM   9323  N N   . LEU D 1 182 ? 118.322 113.739 97.454  1.00 35.83  ? 128 LEU D N   1 
ATOM   9324  C CA  . LEU D 1 182 ? 119.251 114.677 98.062  1.00 32.69  ? 128 LEU D CA  1 
ATOM   9325  C C   . LEU D 1 182 ? 119.532 114.243 99.490  1.00 37.12  ? 128 LEU D C   1 
ATOM   9326  O O   . LEU D 1 182 ? 118.710 113.581 100.123 1.00 41.85  ? 128 LEU D O   1 
ATOM   9327  C CB  . LEU D 1 182 ? 118.697 116.104 98.060  1.00 31.66  ? 128 LEU D CB  1 
ATOM   9328  C CG  . LEU D 1 182 ? 118.373 116.736 96.711  1.00 34.70  ? 128 LEU D CG  1 
ATOM   9329  C CD1 . LEU D 1 182 ? 117.316 117.801 96.886  1.00 40.45  ? 128 LEU D CD1 1 
ATOM   9330  C CD2 . LEU D 1 182 ? 119.625 117.332 96.105  1.00 41.81  ? 128 LEU D CD2 1 
ATOM   9331  N N   . ARG D 1 183 ? 120.706 114.606 99.990  1.00 33.13  ? 129 ARG D N   1 
ATOM   9332  C CA  . ARG D 1 183 ? 121.050 114.403 101.391 1.00 34.04  ? 129 ARG D CA  1 
ATOM   9333  C C   . ARG D 1 183 ? 121.081 115.768 102.061 1.00 35.65  ? 129 ARG D C   1 
ATOM   9334  O O   . ARG D 1 183 ? 121.888 116.626 101.690 1.00 40.36  ? 129 ARG D O   1 
ATOM   9335  C CB  . ARG D 1 183 ? 122.388 113.683 101.537 1.00 35.85  ? 129 ARG D CB  1 
ATOM   9336  C CG  . ARG D 1 183 ? 122.547 112.975 102.868 1.00 33.62  ? 129 ARG D CG  1 
ATOM   9337  C CD  . ARG D 1 183 ? 123.637 111.928 102.802 1.00 36.13  ? 129 ARG D CD  1 
ATOM   9338  N NE  . ARG D 1 183 ? 124.970 112.512 102.848 1.00 36.89  ? 129 ARG D NE  1 
ATOM   9339  C CZ  . ARG D 1 183 ? 125.700 112.611 103.949 1.00 35.24  ? 129 ARG D CZ  1 
ATOM   9340  N NH1 . ARG D 1 183 ? 125.247 112.187 105.117 1.00 36.38  ? 129 ARG D NH1 1 
ATOM   9341  N NH2 . ARG D 1 183 ? 126.917 113.141 103.875 1.00 32.10  ? 129 ARG D NH2 1 
ATOM   9342  N N   . ILE D 1 184 ? 120.204 115.964 103.042 1.00 33.34  ? 130 ILE D N   1 
ATOM   9343  C CA  . ILE D 1 184 ? 119.925 117.284 103.593 1.00 32.98  ? 130 ILE D CA  1 
ATOM   9344  C C   . ILE D 1 184 ? 120.100 117.247 105.104 1.00 35.33  ? 130 ILE D C   1 
ATOM   9345  O O   . ILE D 1 184 ? 119.588 116.341 105.769 1.00 39.41  ? 130 ILE D O   1 
ATOM   9346  C CB  . ILE D 1 184 ? 118.503 117.756 103.232 1.00 33.83  ? 130 ILE D CB  1 
ATOM   9347  C CG1 . ILE D 1 184 ? 118.294 117.725 101.717 1.00 33.22  ? 130 ILE D CG1 1 
ATOM   9348  C CG2 . ILE D 1 184 ? 118.248 119.148 103.778 1.00 39.81  ? 130 ILE D CG2 1 
ATOM   9349  C CD1 . ILE D 1 184 ? 116.883 118.045 101.292 1.00 32.58  ? 130 ILE D CD1 1 
ATOM   9350  N N   . THR D 1 185 ? 120.816 118.235 105.638 1.00 35.68  ? 131 THR D N   1 
ATOM   9351  C CA  . THR D 1 185 ? 120.913 118.476 107.074 1.00 40.81  ? 131 THR D CA  1 
ATOM   9352  C C   . THR D 1 185 ? 120.164 119.768 107.374 1.00 43.42  ? 131 THR D C   1 
ATOM   9353  O O   . THR D 1 185 ? 120.649 120.859 107.061 1.00 48.56  ? 131 THR D O   1 
ATOM   9354  C CB  . THR D 1 185 ? 122.368 118.569 107.526 1.00 42.40  ? 131 THR D CB  1 
ATOM   9355  O OG1 . THR D 1 185 ? 123.028 117.322 107.284 1.00 48.48  ? 131 THR D OG1 1 
ATOM   9356  C CG2 . THR D 1 185 ? 122.446 118.898 109.007 1.00 39.57  ? 131 THR D CG2 1 
ATOM   9357  N N   . THR D 1 186 ? 118.988 119.644 107.981 1.00 45.27  ? 132 THR D N   1 
ATOM   9358  C CA  . THR D 1 186 ? 118.099 120.769 108.224 1.00 48.45  ? 132 THR D CA  1 
ATOM   9359  C C   . THR D 1 186 ? 117.965 121.027 109.718 1.00 48.35  ? 132 THR D C   1 
ATOM   9360  O O   . THR D 1 186 ? 117.801 120.094 110.508 1.00 50.18  ? 132 THR D O   1 
ATOM   9361  C CB  . THR D 1 186 ? 116.716 120.516 107.613 1.00 51.25  ? 132 THR D CB  1 
ATOM   9362  O OG1 . THR D 1 186 ? 115.772 121.454 108.142 1.00 54.50  ? 132 THR D OG1 1 
ATOM   9363  C CG2 . THR D 1 186 ? 116.243 119.100 107.910 1.00 42.44  ? 132 THR D CG2 1 
ATOM   9364  N N   . THR D 1 187 ? 118.040 122.300 110.102 1.00 49.08  ? 133 THR D N   1 
ATOM   9365  C CA  . THR D 1 187 ? 117.825 122.722 111.485 1.00 49.90  ? 133 THR D CA  1 
ATOM   9366  C C   . THR D 1 187 ? 116.379 123.192 111.582 1.00 47.99  ? 133 THR D C   1 
ATOM   9367  O O   . THR D 1 187 ? 116.071 124.363 111.374 1.00 55.58  ? 133 THR D O   1 
ATOM   9368  C CB  . THR D 1 187 ? 118.804 123.820 111.885 1.00 51.63  ? 133 THR D CB  1 
ATOM   9369  O OG1 . THR D 1 187 ? 120.139 123.411 111.570 1.00 56.62  ? 133 THR D OG1 1 
ATOM   9370  C CG2 . THR D 1 187 ? 118.710 124.095 113.375 1.00 53.59  ? 133 THR D CG2 1 
ATOM   9371  N N   . ALA D 1 188 ? 115.482 122.265 111.894 1.00 44.98  ? 134 ALA D N   1 
ATOM   9372  C CA  . ALA D 1 188 ? 114.058 122.563 111.901 1.00 47.58  ? 134 ALA D CA  1 
ATOM   9373  C C   . ALA D 1 188 ? 113.637 123.132 113.247 1.00 51.43  ? 134 ALA D C   1 
ATOM   9374  O O   . ALA D 1 188 ? 114.066 122.654 114.300 1.00 60.52  ? 134 ALA D O   1 
ATOM   9375  C CB  . ALA D 1 188 ? 113.244 121.310 111.582 1.00 48.42  ? 134 ALA D CB  1 
ATOM   9376  N N   . ALA D 1 189 ? 112.782 124.150 113.203 1.00 48.35  ? 135 ALA D N   1 
ATOM   9377  C CA  . ALA D 1 189 ? 112.308 124.806 114.413 1.00 49.72  ? 135 ALA D CA  1 
ATOM   9378  C C   . ALA D 1 189 ? 111.240 123.968 115.101 1.00 60.39  ? 135 ALA D C   1 
ATOM   9379  O O   . ALA D 1 189 ? 110.373 123.381 114.448 1.00 60.42  ? 135 ALA D O   1 
ATOM   9380  C CB  . ALA D 1 189 ? 111.752 126.191 114.086 1.00 41.19  ? 135 ALA D CB  1 
ATOM   9381  N N   . CYS D 1 190 ? 111.304 123.917 116.432 1.00 65.71  ? 136 CYS D N   1 
ATOM   9382  C CA  . CYS D 1 190 ? 110.354 123.143 117.232 1.00 67.74  ? 136 CYS D CA  1 
ATOM   9383  C C   . CYS D 1 190 ? 110.096 123.895 118.534 1.00 76.60  ? 136 CYS D C   1 
ATOM   9384  O O   . CYS D 1 190 ? 110.933 123.880 119.440 1.00 79.61  ? 136 CYS D O   1 
ATOM   9385  C CB  . CYS D 1 190 ? 110.879 121.737 117.499 1.00 67.30  ? 136 CYS D CB  1 
ATOM   9386  S SG  . CYS D 1 190 ? 109.790 120.710 118.514 1.00 85.92  ? 136 CYS D SG  1 
ATOM   9387  N N   . MET D 1 191 ? 108.938 124.545 118.625 1.00 76.35  ? 137 MET D N   1 
ATOM   9388  C CA  . MET D 1 191 ? 108.538 125.185 119.871 1.00 77.17  ? 137 MET D CA  1 
ATOM   9389  C C   . MET D 1 191 ? 108.189 124.122 120.904 1.00 77.69  ? 137 MET D C   1 
ATOM   9390  O O   . MET D 1 191 ? 107.458 123.172 120.609 1.00 81.44  ? 137 MET D O   1 
ATOM   9391  C CB  . MET D 1 191 ? 107.347 126.112 119.634 1.00 76.19  ? 137 MET D CB  1 
ATOM   9392  C CG  . MET D 1 191 ? 107.641 127.302 118.729 1.00 84.62  ? 137 MET D CG  1 
ATOM   9393  S SD  . MET D 1 191 ? 108.780 128.498 119.457 1.00 116.79 ? 137 MET D SD  1 
ATOM   9394  C CE  . MET D 1 191 ? 110.318 128.064 118.647 1.00 91.71  ? 137 MET D CE  1 
ATOM   9395  N N   . MET D 1 192 ? 108.711 124.280 122.116 1.00 73.83  ? 138 MET D N   1 
ATOM   9396  C CA  . MET D 1 192 ? 108.608 123.260 123.149 1.00 73.88  ? 138 MET D CA  1 
ATOM   9397  C C   . MET D 1 192 ? 107.934 123.818 124.394 1.00 77.93  ? 138 MET D C   1 
ATOM   9398  O O   . MET D 1 192 ? 108.200 124.952 124.804 1.00 77.73  ? 138 MET D O   1 
ATOM   9399  C CB  . MET D 1 192 ? 109.988 122.711 123.508 1.00 74.34  ? 138 MET D CB  1 
ATOM   9400  C CG  . MET D 1 192 ? 110.720 122.117 122.327 1.00 76.96  ? 138 MET D CG  1 
ATOM   9401  S SD  . MET D 1 192 ? 112.362 121.512 122.735 1.00 79.52  ? 138 MET D SD  1 
ATOM   9402  C CE  . MET D 1 192 ? 112.925 121.026 121.109 1.00 76.68  ? 138 MET D CE  1 
ATOM   9403  N N   . ASP D 1 193 ? 107.063 123.007 124.992 1.00 78.43  ? 139 ASP D N   1 
ATOM   9404  C CA  . ASP D 1 193 ? 106.400 123.348 126.249 1.00 78.11  ? 139 ASP D CA  1 
ATOM   9405  C C   . ASP D 1 193 ? 107.248 122.791 127.385 1.00 76.03  ? 139 ASP D C   1 
ATOM   9406  O O   . ASP D 1 193 ? 107.095 121.641 127.800 1.00 75.42  ? 139 ASP D O   1 
ATOM   9407  C CB  . ASP D 1 193 ? 104.981 122.796 126.278 1.00 79.20  ? 139 ASP D CB  1 
ATOM   9408  C CG  . ASP D 1 193 ? 104.197 123.269 127.483 1.00 85.28  ? 139 ASP D CG  1 
ATOM   9409  O OD1 . ASP D 1 193 ? 104.688 124.168 128.197 1.00 87.14  ? 139 ASP D OD1 1 
ATOM   9410  O OD2 . ASP D 1 193 ? 103.090 122.743 127.718 1.00 87.50  ? 139 ASP D OD2 1 
ATOM   9411  N N   . LEU D 1 194 ? 108.155 123.620 127.897 1.00 70.69  ? 140 LEU D N   1 
ATOM   9412  C CA  . LEU D 1 194 ? 109.099 123.215 128.928 1.00 69.86  ? 140 LEU D CA  1 
ATOM   9413  C C   . LEU D 1 194 ? 108.559 123.409 130.339 1.00 75.17  ? 140 LEU D C   1 
ATOM   9414  O O   . LEU D 1 194 ? 109.349 123.539 131.281 1.00 76.17  ? 140 LEU D O   1 
ATOM   9415  C CB  . LEU D 1 194 ? 110.413 123.981 128.767 1.00 67.82  ? 140 LEU D CB  1 
ATOM   9416  C CG  . LEU D 1 194 ? 111.199 123.721 127.485 1.00 66.72  ? 140 LEU D CG  1 
ATOM   9417  C CD1 . LEU D 1 194 ? 112.451 124.578 127.456 1.00 72.72  ? 140 LEU D CD1 1 
ATOM   9418  C CD2 . LEU D 1 194 ? 111.555 122.250 127.373 1.00 64.92  ? 140 LEU D CD2 1 
ATOM   9419  N N   . ARG D 1 195 ? 107.236 123.447 130.508 1.00 74.25  ? 141 ARG D N   1 
ATOM   9420  C CA  . ARG D 1 195 ? 106.672 123.588 131.846 1.00 75.13  ? 141 ARG D CA  1 
ATOM   9421  C C   . ARG D 1 195 ? 107.030 122.397 132.725 1.00 73.89  ? 141 ARG D C   1 
ATOM   9422  O O   . ARG D 1 195 ? 107.371 122.564 133.901 1.00 76.76  ? 141 ARG D O   1 
ATOM   9423  C CB  . ARG D 1 195 ? 105.157 123.756 131.767 1.00 78.32  ? 141 ARG D CB  1 
ATOM   9424  C CG  . ARG D 1 195 ? 104.708 125.125 131.300 1.00 82.70  ? 141 ARG D CG  1 
ATOM   9425  C CD  . ARG D 1 195 ? 103.195 125.203 131.249 1.00 88.41  ? 141 ARG D CD  1 
ATOM   9426  N NE  . ARG D 1 195 ? 102.727 126.525 130.852 1.00 96.51  ? 141 ARG D NE  1 
ATOM   9427  C CZ  . ARG D 1 195 ? 102.556 126.913 129.596 1.00 96.83  ? 141 ARG D CZ  1 
ATOM   9428  N NH1 . ARG D 1 195 ? 102.821 126.106 128.581 1.00 96.72  ? 141 ARG D NH1 1 
ATOM   9429  N NH2 . ARG D 1 195 ? 102.109 128.141 129.352 1.00 96.33  ? 141 ARG D NH2 1 
ATOM   9430  N N   . ARG D 1 196 ? 106.964 121.187 132.172 1.00 66.11  ? 142 ARG D N   1 
ATOM   9431  C CA  . ARG D 1 196 ? 107.240 119.969 132.918 1.00 58.57  ? 142 ARG D CA  1 
ATOM   9432  C C   . ARG D 1 196 ? 108.681 119.499 132.764 1.00 59.95  ? 142 ARG D C   1 
ATOM   9433  O O   . ARG D 1 196 ? 108.969 118.322 133.002 1.00 60.37  ? 142 ARG D O   1 
ATOM   9434  C CB  . ARG D 1 196 ? 106.271 118.867 132.488 1.00 56.54  ? 142 ARG D CB  1 
ATOM   9435  C CG  . ARG D 1 196 ? 104.813 119.225 132.715 1.00 61.14  ? 142 ARG D CG  1 
ATOM   9436  C CD  . ARG D 1 196 ? 103.887 118.390 131.852 1.00 70.30  ? 142 ARG D CD  1 
ATOM   9437  N NE  . ARG D 1 196 ? 103.880 116.983 132.234 1.00 73.29  ? 142 ARG D NE  1 
ATOM   9438  C CZ  . ARG D 1 196 ? 102.966 116.426 133.016 1.00 77.00  ? 142 ARG D CZ  1 
ATOM   9439  N NH1 . ARG D 1 196 ? 101.979 117.136 133.540 1.00 74.43  ? 142 ARG D NH1 1 
ATOM   9440  N NH2 . ARG D 1 196 ? 103.039 115.124 133.274 1.00 78.86  ? 142 ARG D NH2 1 
ATOM   9441  N N   . TYR D 1 197 ? 109.586 120.392 132.376 1.00 61.06  ? 143 TYR D N   1 
ATOM   9442  C CA  . TYR D 1 197 ? 110.991 120.043 132.259 1.00 58.46  ? 143 TYR D CA  1 
ATOM   9443  C C   . TYR D 1 197 ? 111.570 119.732 133.640 1.00 63.55  ? 143 TYR D C   1 
ATOM   9444  O O   . TYR D 1 197 ? 111.238 120.398 134.624 1.00 73.25  ? 143 TYR D O   1 
ATOM   9445  C CB  . TYR D 1 197 ? 111.756 121.192 131.606 1.00 60.03  ? 143 TYR D CB  1 
ATOM   9446  C CG  . TYR D 1 197 ? 113.240 120.965 131.436 1.00 62.25  ? 143 TYR D CG  1 
ATOM   9447  C CD1 . TYR D 1 197 ? 113.740 120.339 130.303 1.00 69.17  ? 143 TYR D CD1 1 
ATOM   9448  C CD2 . TYR D 1 197 ? 114.142 121.394 132.398 1.00 61.86  ? 143 TYR D CD2 1 
ATOM   9449  C CE1 . TYR D 1 197 ? 115.096 120.137 130.140 1.00 68.54  ? 143 TYR D CE1 1 
ATOM   9450  C CE2 . TYR D 1 197 ? 115.497 121.196 132.243 1.00 67.04  ? 143 TYR D CE2 1 
ATOM   9451  C CZ  . TYR D 1 197 ? 115.969 120.568 131.113 1.00 66.25  ? 143 TYR D CZ  1 
ATOM   9452  O OH  . TYR D 1 197 ? 117.320 120.370 130.957 1.00 70.35  ? 143 TYR D OH  1 
ATOM   9453  N N   . PRO D 1 198 ? 112.448 118.725 133.744 1.00 61.16  ? 144 PRO D N   1 
ATOM   9454  C CA  . PRO D 1 198 ? 112.936 117.839 132.683 1.00 60.01  ? 144 PRO D CA  1 
ATOM   9455  C C   . PRO D 1 198 ? 112.186 116.517 132.612 1.00 61.82  ? 144 PRO D C   1 
ATOM   9456  O O   . PRO D 1 198 ? 112.804 115.467 132.481 1.00 66.87  ? 144 PRO D O   1 
ATOM   9457  C CB  . PRO D 1 198 ? 114.396 117.631 133.085 1.00 61.04  ? 144 PRO D CB  1 
ATOM   9458  C CG  . PRO D 1 198 ? 114.320 117.563 134.588 1.00 58.04  ? 144 PRO D CG  1 
ATOM   9459  C CD  . PRO D 1 198 ? 113.225 118.540 134.984 1.00 60.75  ? 144 PRO D CD  1 
ATOM   9460  N N   . LEU D 1 199 ? 110.857 116.531 132.697 1.00 59.24  ? 145 LEU D N   1 
ATOM   9461  C CA  . LEU D 1 199 ? 110.044 115.325 132.591 1.00 55.94  ? 145 LEU D CA  1 
ATOM   9462  C C   . LEU D 1 199 ? 109.045 115.441 131.445 1.00 60.52  ? 145 LEU D C   1 
ATOM   9463  O O   . LEU D 1 199 ? 107.987 114.810 131.466 1.00 60.76  ? 145 LEU D O   1 
ATOM   9464  C CB  . LEU D 1 199 ? 109.312 115.036 133.900 1.00 56.84  ? 145 LEU D CB  1 
ATOM   9465  C CG  . LEU D 1 199 ? 110.101 114.695 135.168 1.00 59.40  ? 145 LEU D CG  1 
ATOM   9466  C CD1 . LEU D 1 199 ? 110.673 115.940 135.828 1.00 57.74  ? 145 LEU D CD1 1 
ATOM   9467  C CD2 . LEU D 1 199 ? 109.216 113.936 136.143 1.00 64.08  ? 145 LEU D CD2 1 
ATOM   9468  N N   . ASP D 1 200 ? 109.373 116.245 130.442 1.00 66.82  ? 146 ASP D N   1 
ATOM   9469  C CA  . ASP D 1 200 ? 108.439 116.638 129.400 1.00 64.20  ? 146 ASP D CA  1 
ATOM   9470  C C   . ASP D 1 200 ? 108.488 115.685 128.212 1.00 68.28  ? 146 ASP D C   1 
ATOM   9471  O O   . ASP D 1 200 ? 109.461 114.959 127.999 1.00 70.39  ? 146 ASP D O   1 
ATOM   9472  C CB  . ASP D 1 200 ? 108.740 118.062 128.930 1.00 64.58  ? 146 ASP D CB  1 
ATOM   9473  C CG  . ASP D 1 200 ? 110.165 118.221 128.443 1.00 67.00  ? 146 ASP D CG  1 
ATOM   9474  O OD1 . ASP D 1 200 ? 111.051 117.502 128.951 1.00 66.87  ? 146 ASP D OD1 1 
ATOM   9475  O OD2 . ASP D 1 200 ? 110.400 119.064 127.553 1.00 73.76  ? 146 ASP D OD2 1 
ATOM   9476  N N   . GLU D 1 201 ? 107.408 115.705 127.435 1.00 71.87  ? 147 GLU D N   1 
ATOM   9477  C CA  . GLU D 1 201 ? 107.294 114.957 126.188 1.00 70.15  ? 147 GLU D CA  1 
ATOM   9478  C C   . GLU D 1 201 ? 106.983 115.954 125.080 1.00 65.98  ? 147 GLU D C   1 
ATOM   9479  O O   . GLU D 1 201 ? 105.887 116.525 125.044 1.00 66.37  ? 147 GLU D O   1 
ATOM   9480  C CB  . GLU D 1 201 ? 106.209 113.887 126.287 1.00 74.11  ? 147 GLU D CB  1 
ATOM   9481  C CG  . GLU D 1 201 ? 106.028 113.068 125.026 1.00 78.62  ? 147 GLU D CG  1 
ATOM   9482  C CD  . GLU D 1 201 ? 104.847 112.126 125.111 1.00 87.43  ? 147 GLU D CD  1 
ATOM   9483  O OE1 . GLU D 1 201 ? 103.996 112.317 126.005 1.00 81.26  ? 147 GLU D OE1 1 
ATOM   9484  O OE2 . GLU D 1 201 ? 104.770 111.191 124.287 1.00 91.34  ? 147 GLU D OE2 1 
ATOM   9485  N N   . GLN D 1 202 ? 107.938 116.163 124.182 1.00 63.03  ? 148 GLN D N   1 
ATOM   9486  C CA  . GLN D 1 202 ? 107.818 117.179 123.148 1.00 64.84  ? 148 GLN D CA  1 
ATOM   9487  C C   . GLN D 1 202 ? 107.383 116.564 121.823 1.00 65.60  ? 148 GLN D C   1 
ATOM   9488  O O   . GLN D 1 202 ? 107.489 115.357 121.604 1.00 68.87  ? 148 GLN D O   1 
ATOM   9489  C CB  . GLN D 1 202 ? 109.142 117.927 122.970 1.00 64.95  ? 148 GLN D CB  1 
ATOM   9490  C CG  . GLN D 1 202 ? 109.669 118.577 124.243 1.00 65.84  ? 148 GLN D CG  1 
ATOM   9491  C CD  . GLN D 1 202 ? 108.788 119.709 124.743 1.00 70.56  ? 148 GLN D CD  1 
ATOM   9492  O OE1 . GLN D 1 202 ? 107.908 120.192 124.032 1.00 75.28  ? 148 GLN D OE1 1 
ATOM   9493  N NE2 . GLN D 1 202 ? 109.027 120.141 125.975 1.00 70.72  ? 148 GLN D NE2 1 
ATOM   9494  N N   . ASN D 1 203 ? 106.889 117.422 120.935 1.00 65.65  ? 149 ASN D N   1 
ATOM   9495  C CA  . ASN D 1 203 ? 106.402 117.022 119.618 1.00 64.45  ? 149 ASN D CA  1 
ATOM   9496  C C   . ASN D 1 203 ? 107.021 117.959 118.589 1.00 62.34  ? 149 ASN D C   1 
ATOM   9497  O O   . ASN D 1 203 ? 106.726 119.158 118.581 1.00 65.37  ? 149 ASN D O   1 
ATOM   9498  C CB  . ASN D 1 203 ? 104.872 117.061 119.572 1.00 66.66  ? 149 ASN D CB  1 
ATOM   9499  C CG  . ASN D 1 203 ? 104.308 116.792 118.187 1.00 69.70  ? 149 ASN D CG  1 
ATOM   9500  O OD1 . ASN D 1 203 ? 105.001 116.300 117.298 1.00 70.28  ? 149 ASN D OD1 1 
ATOM   9501  N ND2 . ASN D 1 203 ? 103.030 117.111 118.006 1.00 73.38  ? 149 ASN D ND2 1 
ATOM   9502  N N   . CYS D 1 204 ? 107.878 117.417 117.726 1.00 57.25  ? 150 CYS D N   1 
ATOM   9503  C CA  . CYS D 1 204 ? 108.609 118.210 116.746 1.00 60.99  ? 150 CYS D CA  1 
ATOM   9504  C C   . CYS D 1 204 ? 108.270 117.744 115.338 1.00 62.95  ? 150 CYS D C   1 
ATOM   9505  O O   . CYS D 1 204 ? 108.259 116.543 115.058 1.00 64.80  ? 150 CYS D O   1 
ATOM   9506  C CB  . CYS D 1 204 ? 110.119 118.123 116.978 1.00 65.51  ? 150 CYS D CB  1 
ATOM   9507  S SG  . CYS D 1 204 ? 110.676 118.882 118.521 1.00 96.88  ? 150 CYS D SG  1 
ATOM   9508  N N   . THR D 1 205 ? 108.014 118.697 114.447 1.00 59.89  ? 151 THR D N   1 
ATOM   9509  C CA  . THR D 1 205 ? 107.509 118.391 113.118 1.00 50.47  ? 151 THR D CA  1 
ATOM   9510  C C   . THR D 1 205 ? 108.473 118.863 112.038 1.00 49.49  ? 151 THR D C   1 
ATOM   9511  O O   . THR D 1 205 ? 109.410 119.627 112.283 1.00 52.72  ? 151 THR D O   1 
ATOM   9512  C CB  . THR D 1 205 ? 106.133 119.029 112.890 1.00 54.94  ? 151 THR D CB  1 
ATOM   9513  O OG1 . THR D 1 205 ? 106.253 120.456 112.949 1.00 58.48  ? 151 THR D OG1 1 
ATOM   9514  C CG2 . THR D 1 205 ? 105.148 118.565 113.948 1.00 63.03  ? 151 THR D CG2 1 
ATOM   9515  N N   . LEU D 1 206 ? 108.214 118.380 110.827 1.00 51.42  ? 152 LEU D N   1 
ATOM   9516  C CA  . LEU D 1 206 ? 108.909 118.805 109.619 1.00 47.20  ? 152 LEU D CA  1 
ATOM   9517  C C   . LEU D 1 206 ? 107.858 118.967 108.534 1.00 42.35  ? 152 LEU D C   1 
ATOM   9518  O O   . LEU D 1 206 ? 107.176 117.998 108.183 1.00 44.65  ? 152 LEU D O   1 
ATOM   9519  C CB  . LEU D 1 206 ? 109.976 117.793 109.194 1.00 42.31  ? 152 LEU D CB  1 
ATOM   9520  C CG  . LEU D 1 206 ? 110.749 118.116 107.913 1.00 45.00  ? 152 LEU D CG  1 
ATOM   9521  C CD1 . LEU D 1 206 ? 111.636 119.337 108.106 1.00 42.46  ? 152 LEU D CD1 1 
ATOM   9522  C CD2 . LEU D 1 206 ? 111.570 116.919 107.464 1.00 39.95  ? 152 LEU D CD2 1 
ATOM   9523  N N   . GLU D 1 207 ? 107.717 120.188 108.027 1.00 35.15  ? 153 GLU D N   1 
ATOM   9524  C CA  . GLU D 1 207 ? 106.668 120.545 107.082 1.00 38.01  ? 153 GLU D CA  1 
ATOM   9525  C C   . GLU D 1 207 ? 107.288 120.732 105.706 1.00 38.23  ? 153 GLU D C   1 
ATOM   9526  O O   . GLU D 1 207 ? 108.183 121.564 105.531 1.00 43.84  ? 153 GLU D O   1 
ATOM   9527  C CB  . GLU D 1 207 ? 105.949 121.817 107.527 1.00 50.57  ? 153 GLU D CB  1 
ATOM   9528  C CG  . GLU D 1 207 ? 105.439 121.776 108.958 1.00 54.76  ? 153 GLU D CG  1 
ATOM   9529  C CD  . GLU D 1 207 ? 104.155 120.987 109.097 1.00 61.34  ? 153 GLU D CD  1 
ATOM   9530  O OE1 . GLU D 1 207 ? 103.276 121.125 108.222 1.00 58.63  ? 153 GLU D OE1 1 
ATOM   9531  O OE2 . GLU D 1 207 ? 104.024 120.229 110.080 1.00 63.43  ? 153 GLU D OE2 1 
ATOM   9532  N N   . ILE D 1 208 ? 106.804 119.967 104.735 1.00 39.37  ? 154 ILE D N   1 
ATOM   9533  C CA  . ILE D 1 208 ? 107.315 119.972 103.371 1.00 39.28  ? 154 ILE D CA  1 
ATOM   9534  C C   . ILE D 1 208 ? 106.237 120.557 102.473 1.00 43.19  ? 154 ILE D C   1 
ATOM   9535  O O   . ILE D 1 208 ? 105.079 120.126 102.524 1.00 49.90  ? 154 ILE D O   1 
ATOM   9536  C CB  . ILE D 1 208 ? 107.702 118.552 102.924 1.00 37.01  ? 154 ILE D CB  1 
ATOM   9537  C CG1 . ILE D 1 208 ? 108.777 117.985 103.852 1.00 37.59  ? 154 ILE D CG1 1 
ATOM   9538  C CG2 . ILE D 1 208 ? 108.170 118.556 101.492 1.00 38.81  ? 154 ILE D CG2 1 
ATOM   9539  C CD1 . ILE D 1 208 ? 109.048 116.518 103.645 1.00 37.04  ? 154 ILE D CD1 1 
ATOM   9540  N N   . GLU D 1 209 ? 106.609 121.540 101.656 1.00 39.31  ? 155 GLU D N   1 
ATOM   9541  C CA  . GLU D 1 209 ? 105.610 122.254 100.880 1.00 40.60  ? 155 GLU D CA  1 
ATOM   9542  C C   . GLU D 1 209 ? 106.200 122.693 99.548  1.00 44.50  ? 155 GLU D C   1 
ATOM   9543  O O   . GLU D 1 209 ? 107.411 122.890 99.420  1.00 49.38  ? 155 GLU D O   1 
ATOM   9544  C CB  . GLU D 1 209 ? 105.083 123.458 101.669 1.00 45.83  ? 155 GLU D CB  1 
ATOM   9545  C CG  . GLU D 1 209 ? 103.942 124.207 101.013 1.00 55.10  ? 155 GLU D CG  1 
ATOM   9546  C CD  . GLU D 1 209 ? 103.153 125.031 102.003 1.00 69.30  ? 155 GLU D CD  1 
ATOM   9547  O OE1 . GLU D 1 209 ? 102.822 124.500 103.083 1.00 69.21  ? 155 GLU D OE1 1 
ATOM   9548  O OE2 . GLU D 1 209 ? 102.868 126.208 101.704 1.00 75.83  ? 155 GLU D OE2 1 
ATOM   9549  N N   . SER D 1 210 ? 105.328 122.832 98.554  1.00 43.82  ? 156 SER D N   1 
ATOM   9550  C CA  . SER D 1 210 ? 105.712 123.422 97.282  1.00 41.96  ? 156 SER D CA  1 
ATOM   9551  C C   . SER D 1 210 ? 105.670 124.939 97.386  1.00 46.71  ? 156 SER D C   1 
ATOM   9552  O O   . SER D 1 210 ? 104.733 125.511 97.949  1.00 53.21  ? 156 SER D O   1 
ATOM   9553  C CB  . SER D 1 210 ? 104.784 122.948 96.166  1.00 43.64  ? 156 SER D CB  1 
ATOM   9554  O OG  . SER D 1 210 ? 105.103 123.585 94.944  1.00 49.40  ? 156 SER D OG  1 
ATOM   9555  N N   . TYR D 1 211 ? 106.694 125.592 96.839  1.00 46.36  ? 157 TYR D N   1 
ATOM   9556  C CA  . TYR D 1 211 ? 106.848 127.026 97.057  1.00 45.82  ? 157 TYR D CA  1 
ATOM   9557  C C   . TYR D 1 211 ? 105.981 127.844 96.104  1.00 47.78  ? 157 TYR D C   1 
ATOM   9558  O O   . TYR D 1 211 ? 105.110 128.603 96.540  1.00 49.68  ? 157 TYR D O   1 
ATOM   9559  C CB  . TYR D 1 211 ? 108.319 127.425 96.921  1.00 41.68  ? 157 TYR D CB  1 
ATOM   9560  C CG  . TYR D 1 211 ? 108.607 128.789 97.493  1.00 42.81  ? 157 TYR D CG  1 
ATOM   9561  C CD1 . TYR D 1 211 ? 108.845 128.955 98.848  1.00 42.82  ? 157 TYR D CD1 1 
ATOM   9562  C CD2 . TYR D 1 211 ? 108.622 129.913 96.684  1.00 41.86  ? 157 TYR D CD2 1 
ATOM   9563  C CE1 . TYR D 1 211 ? 109.098 130.199 99.379  1.00 40.75  ? 157 TYR D CE1 1 
ATOM   9564  C CE2 . TYR D 1 211 ? 108.875 131.161 97.207  1.00 40.11  ? 157 TYR D CE2 1 
ATOM   9565  C CZ  . TYR D 1 211 ? 109.112 131.298 98.554  1.00 41.27  ? 157 TYR D CZ  1 
ATOM   9566  O OH  . TYR D 1 211 ? 109.362 132.539 99.079  1.00 45.84  ? 157 TYR D OH  1 
ATOM   9567  N N   . GLY D 1 212 ? 106.209 127.707 94.802  1.00 44.92  ? 158 GLY D N   1 
ATOM   9568  C CA  . GLY D 1 212 ? 105.550 128.573 93.844  1.00 47.96  ? 158 GLY D CA  1 
ATOM   9569  C C   . GLY D 1 212 ? 104.361 127.975 93.124  1.00 50.49  ? 158 GLY D C   1 
ATOM   9570  O O   . GLY D 1 212 ? 103.601 128.701 92.479  1.00 59.35  ? 158 GLY D O   1 
ATOM   9571  N N   . TYR D 1 213 ? 104.172 126.664 93.232  1.00 46.37  ? 159 TYR D N   1 
ATOM   9572  C CA  . TYR D 1 213 ? 103.114 125.969 92.512  1.00 48.65  ? 159 TYR D CA  1 
ATOM   9573  C C   . TYR D 1 213 ? 101.952 125.676 93.449  1.00 49.68  ? 159 TYR D C   1 
ATOM   9574  O O   . TYR D 1 213 ? 102.155 125.190 94.566  1.00 54.52  ? 159 TYR D O   1 
ATOM   9575  C CB  . TYR D 1 213 ? 103.630 124.669 91.898  1.00 50.45  ? 159 TYR D CB  1 
ATOM   9576  C CG  . TYR D 1 213 ? 104.682 124.865 90.836  1.00 46.65  ? 159 TYR D CG  1 
ATOM   9577  C CD1 . TYR D 1 213 ? 104.328 125.166 89.530  1.00 48.22  ? 159 TYR D CD1 1 
ATOM   9578  C CD2 . TYR D 1 213 ? 106.028 124.742 91.137  1.00 45.20  ? 159 TYR D CD2 1 
ATOM   9579  C CE1 . TYR D 1 213 ? 105.286 125.342 88.557  1.00 49.57  ? 159 TYR D CE1 1 
ATOM   9580  C CE2 . TYR D 1 213 ? 106.993 124.917 90.170  1.00 45.84  ? 159 TYR D CE2 1 
ATOM   9581  C CZ  . TYR D 1 213 ? 106.617 125.217 88.882  1.00 49.39  ? 159 TYR D CZ  1 
ATOM   9582  O OH  . TYR D 1 213 ? 107.575 125.392 87.912  1.00 57.37  ? 159 TYR D OH  1 
ATOM   9583  N N   . THR D 1 214 ? 100.740 125.968 92.990  1.00 51.02  ? 160 THR D N   1 
ATOM   9584  C CA  . THR D 1 214 ? 99.538  125.705 93.767  1.00 58.30  ? 160 THR D CA  1 
ATOM   9585  C C   . THR D 1 214 ? 99.131  124.244 93.582  1.00 57.83  ? 160 THR D C   1 
ATOM   9586  O O   . THR D 1 214 ? 99.859  123.440 92.995  1.00 62.10  ? 160 THR D O   1 
ATOM   9587  C CB  . THR D 1 214 ? 98.421  126.661 93.357  1.00 66.59  ? 160 THR D CB  1 
ATOM   9588  O OG1 . THR D 1 214 ? 97.826  126.204 92.137  1.00 70.02  ? 160 THR D OG1 1 
ATOM   9589  C CG2 . THR D 1 214 ? 98.976  128.061 93.142  1.00 68.37  ? 160 THR D CG2 1 
ATOM   9590  N N   . THR D 1 215 ? 97.947  123.884 94.080  1.00 54.13  ? 161 THR D N   1 
ATOM   9591  C CA  . THR D 1 215 ? 97.456  122.521 93.920  1.00 57.08  ? 161 THR D CA  1 
ATOM   9592  C C   . THR D 1 215 ? 96.989  122.223 92.504  1.00 64.86  ? 161 THR D C   1 
ATOM   9593  O O   . THR D 1 215 ? 96.723  121.058 92.192  1.00 67.98  ? 161 THR D O   1 
ATOM   9594  C CB  . THR D 1 215 ? 96.313  122.251 94.896  1.00 66.32  ? 161 THR D CB  1 
ATOM   9595  O OG1 . THR D 1 215 ? 95.321  123.277 94.768  1.00 76.95  ? 161 THR D OG1 1 
ATOM   9596  C CG2 . THR D 1 215 ? 96.832  122.221 96.322  1.00 65.97  ? 161 THR D CG2 1 
ATOM   9597  N N   . ASP D 1 216 ? 96.874  123.236 91.647  1.00 69.30  ? 162 ASP D N   1 
ATOM   9598  C CA  . ASP D 1 216 ? 96.542  123.020 90.247  1.00 70.89  ? 162 ASP D CA  1 
ATOM   9599  C C   . ASP D 1 216 ? 97.767  122.754 89.387  1.00 69.31  ? 162 ASP D C   1 
ATOM   9600  O O   . ASP D 1 216 ? 97.619  122.439 88.202  1.00 73.05  ? 162 ASP D O   1 
ATOM   9601  C CB  . ASP D 1 216 ? 95.782  124.229 89.692  1.00 71.33  ? 162 ASP D CB  1 
ATOM   9602  C CG  . ASP D 1 216 ? 94.496  124.500 90.443  1.00 83.27  ? 162 ASP D CG  1 
ATOM   9603  O OD1 . ASP D 1 216 ? 93.929  123.545 91.013  1.00 86.70  ? 162 ASP D OD1 1 
ATOM   9604  O OD2 . ASP D 1 216 ? 94.052  125.667 90.463  1.00 85.29  ? 162 ASP D OD2 1 
ATOM   9605  N N   . ASP D 1 217 ? 98.968  122.869 89.953  1.00 63.02  ? 163 ASP D N   1 
ATOM   9606  C CA  . ASP D 1 217 ? 100.196 122.610 89.223  1.00 60.18  ? 163 ASP D CA  1 
ATOM   9607  C C   . ASP D 1 217 ? 101.045 121.506 89.829  1.00 58.86  ? 163 ASP D C   1 
ATOM   9608  O O   . ASP D 1 217 ? 101.968 121.029 89.160  1.00 63.73  ? 163 ASP D O   1 
ATOM   9609  C CB  . ASP D 1 217 ? 101.042 123.889 89.126  1.00 60.72  ? 163 ASP D CB  1 
ATOM   9610  C CG  . ASP D 1 217 ? 100.448 124.908 88.179  1.00 73.54  ? 163 ASP D CG  1 
ATOM   9611  O OD1 . ASP D 1 217 ? 99.459  124.573 87.493  1.00 83.51  ? 163 ASP D OD1 1 
ATOM   9612  O OD2 . ASP D 1 217 ? 100.966 126.042 88.118  1.00 74.03  ? 163 ASP D OD2 1 
ATOM   9613  N N   . ILE D 1 218 ? 100.765 121.080 91.059  1.00 56.17  ? 164 ILE D N   1 
ATOM   9614  C CA  . ILE D 1 218 ? 101.595 120.086 91.725  1.00 56.29  ? 164 ILE D CA  1 
ATOM   9615  C C   . ILE D 1 218 ? 100.775 119.454 92.838  1.00 55.72  ? 164 ILE D C   1 
ATOM   9616  O O   . ILE D 1 218 ? 99.887  120.088 93.412  1.00 60.74  ? 164 ILE D O   1 
ATOM   9617  C CB  . ILE D 1 218 ? 102.905 120.725 92.254  1.00 47.40  ? 164 ILE D CB  1 
ATOM   9618  C CG1 . ILE D 1 218 ? 103.972 119.660 92.497  1.00 45.96  ? 164 ILE D CG1 1 
ATOM   9619  C CG2 . ILE D 1 218 ? 102.646 121.519 93.520  1.00 48.48  ? 164 ILE D CG2 1 
ATOM   9620  C CD1 . ILE D 1 218 ? 105.333 120.237 92.816  1.00 43.35  ? 164 ILE D CD1 1 
ATOM   9621  N N   . GLU D 1 219 ? 101.060 118.186 93.123  1.00 49.95  ? 165 GLU D N   1 
ATOM   9622  C CA  . GLU D 1 219 ? 100.406 117.461 94.201  1.00 51.52  ? 165 GLU D CA  1 
ATOM   9623  C C   . GLU D 1 219 ? 101.427 116.580 94.900  1.00 53.00  ? 165 GLU D C   1 
ATOM   9624  O O   . GLU D 1 219 ? 102.255 115.941 94.247  1.00 54.44  ? 165 GLU D O   1 
ATOM   9625  C CB  . GLU D 1 219 ? 99.244  116.602 93.690  1.00 55.01  ? 165 GLU D CB  1 
ATOM   9626  C CG  . GLU D 1 219 ? 97.986  117.381 93.364  1.00 59.15  ? 165 GLU D CG  1 
ATOM   9627  C CD  . GLU D 1 219 ? 96.802  116.477 93.094  1.00 65.10  ? 165 GLU D CD  1 
ATOM   9628  O OE1 . GLU D 1 219 ? 97.000  115.246 93.020  1.00 59.73  ? 165 GLU D OE1 1 
ATOM   9629  O OE2 . GLU D 1 219 ? 95.673  116.995 92.962  1.00 70.12  ? 165 GLU D OE2 1 
ATOM   9630  N N   . PHE D 1 220 ? 101.361 116.548 96.226  1.00 45.72  ? 166 PHE D N   1 
ATOM   9631  C CA  . PHE D 1 220 ? 102.271 115.757 97.036  1.00 41.30  ? 166 PHE D CA  1 
ATOM   9632  C C   . PHE D 1 220 ? 101.537 114.582 97.665  1.00 44.48  ? 166 PHE D C   1 
ATOM   9633  O O   . PHE D 1 220 ? 100.343 114.659 97.965  1.00 50.82  ? 166 PHE D O   1 
ATOM   9634  C CB  . PHE D 1 220 ? 102.914 116.600 98.142  1.00 42.95  ? 166 PHE D CB  1 
ATOM   9635  C CG  . PHE D 1 220 ? 103.905 117.608 97.643  1.00 44.93  ? 166 PHE D CG  1 
ATOM   9636  C CD1 . PHE D 1 220 ? 104.352 117.576 96.336  1.00 47.13  ? 166 PHE D CD1 1 
ATOM   9637  C CD2 . PHE D 1 220 ? 104.400 118.583 98.491  1.00 43.44  ? 166 PHE D CD2 1 
ATOM   9638  C CE1 . PHE D 1 220 ? 105.265 118.502 95.882  1.00 44.81  ? 166 PHE D CE1 1 
ATOM   9639  C CE2 . PHE D 1 220 ? 105.314 119.509 98.043  1.00 40.76  ? 166 PHE D CE2 1 
ATOM   9640  C CZ  . PHE D 1 220 ? 105.745 119.470 96.736  1.00 39.82  ? 166 PHE D CZ  1 
ATOM   9641  N N   . TYR D 1 221 ? 102.270 113.489 97.859  1.00 43.25  ? 167 TYR D N   1 
ATOM   9642  C CA  . TYR D 1 221 ? 101.752 112.331 98.568  1.00 44.18  ? 167 TYR D CA  1 
ATOM   9643  C C   . TYR D 1 221 ? 102.932 111.524 99.086  1.00 46.21  ? 167 TYR D C   1 
ATOM   9644  O O   . TYR D 1 221 ? 103.999 111.499 98.469  1.00 47.61  ? 167 TYR D O   1 
ATOM   9645  C CB  . TYR D 1 221 ? 100.853 111.468 97.674  1.00 43.31  ? 167 TYR D CB  1 
ATOM   9646  C CG  . TYR D 1 221 ? 101.561 110.828 96.500  1.00 44.79  ? 167 TYR D CG  1 
ATOM   9647  C CD1 . TYR D 1 221 ? 101.678 111.492 95.287  1.00 45.33  ? 167 TYR D CD1 1 
ATOM   9648  C CD2 . TYR D 1 221 ? 102.101 109.554 96.602  1.00 44.91  ? 167 TYR D CD2 1 
ATOM   9649  C CE1 . TYR D 1 221 ? 102.320 110.907 94.213  1.00 48.57  ? 167 TYR D CE1 1 
ATOM   9650  C CE2 . TYR D 1 221 ? 102.746 108.964 95.536  1.00 44.23  ? 167 TYR D CE2 1 
ATOM   9651  C CZ  . TYR D 1 221 ? 102.852 109.642 94.345  1.00 48.63  ? 167 TYR D CZ  1 
ATOM   9652  O OH  . TYR D 1 221 ? 103.494 109.052 93.282  1.00 50.47  ? 167 TYR D OH  1 
ATOM   9653  N N   . TRP D 1 222 ? 102.732 110.872 100.227 1.00 42.98  ? 168 TRP D N   1 
ATOM   9654  C CA  . TRP D 1 222 ? 103.771 110.028 100.804 1.00 40.18  ? 168 TRP D CA  1 
ATOM   9655  C C   . TRP D 1 222 ? 103.853 108.729 100.017 1.00 44.30  ? 168 TRP D C   1 
ATOM   9656  O O   . TRP D 1 222 ? 102.984 107.862 100.143 1.00 52.25  ? 168 TRP D O   1 
ATOM   9657  C CB  . TRP D 1 222 ? 103.484 109.754 102.276 1.00 42.26  ? 168 TRP D CB  1 
ATOM   9658  C CG  . TRP D 1 222 ? 103.797 110.897 103.181 1.00 39.33  ? 168 TRP D CG  1 
ATOM   9659  C CD1 . TRP D 1 222 ? 102.912 111.619 103.922 1.00 41.57  ? 168 TRP D CD1 1 
ATOM   9660  C CD2 . TRP D 1 222 ? 105.089 111.452 103.444 1.00 37.07  ? 168 TRP D CD2 1 
ATOM   9661  N NE1 . TRP D 1 222 ? 103.572 112.589 104.633 1.00 43.60  ? 168 TRP D NE1 1 
ATOM   9662  C CE2 . TRP D 1 222 ? 104.911 112.508 104.357 1.00 41.12  ? 168 TRP D CE2 1 
ATOM   9663  C CE3 . TRP D 1 222 ? 106.380 111.158 102.997 1.00 39.53  ? 168 TRP D CE3 1 
ATOM   9664  C CZ2 . TRP D 1 222 ? 105.974 113.271 104.830 1.00 38.47  ? 168 TRP D CZ2 1 
ATOM   9665  C CZ3 . TRP D 1 222 ? 107.432 111.915 103.467 1.00 39.07  ? 168 TRP D CZ3 1 
ATOM   9666  C CH2 . TRP D 1 222 ? 107.224 112.960 104.375 1.00 32.90  ? 168 TRP D CH2 1 
ATOM   9667  N N   . ARG D 1 223 ? 104.898 108.588 99.207  1.00 46.44  ? 169 ARG D N   1 
ATOM   9668  C CA  . ARG D 1 223 ? 105.058 107.401 98.380  1.00 48.72  ? 169 ARG D CA  1 
ATOM   9669  C C   . ARG D 1 223 ? 105.367 106.195 99.257  1.00 53.37  ? 169 ARG D C   1 
ATOM   9670  O O   . ARG D 1 223 ? 106.381 106.173 99.960  1.00 51.52  ? 169 ARG D O   1 
ATOM   9671  C CB  . ARG D 1 223 ? 106.165 107.620 97.355  1.00 47.44  ? 169 ARG D CB  1 
ATOM   9672  C CG  . ARG D 1 223 ? 106.362 106.461 96.407  1.00 50.18  ? 169 ARG D CG  1 
ATOM   9673  C CD  . ARG D 1 223 ? 107.388 106.808 95.354  1.00 59.09  ? 169 ARG D CD  1 
ATOM   9674  N NE  . ARG D 1 223 ? 107.581 105.727 94.397  1.00 64.09  ? 169 ARG D NE  1 
ATOM   9675  C CZ  . ARG D 1 223 ? 108.528 104.805 94.491  1.00 68.02  ? 169 ARG D CZ  1 
ATOM   9676  N NH1 . ARG D 1 223 ? 109.393 104.803 95.492  1.00 67.17  ? 169 ARG D NH1 1 
ATOM   9677  N NH2 . ARG D 1 223 ? 108.614 103.865 93.555  1.00 68.66  ? 169 ARG D NH2 1 
ATOM   9678  N N   . GLY D 1 224 ? 104.496 105.191 99.210  1.00 55.76  ? 170 GLY D N   1 
ATOM   9679  C CA  . GLY D 1 224 ? 104.609 104.018 100.051 1.00 55.03  ? 170 GLY D CA  1 
ATOM   9680  C C   . GLY D 1 224 ? 103.618 103.968 101.191 1.00 55.75  ? 170 GLY D C   1 
ATOM   9681  O O   . GLY D 1 224 ? 103.503 102.922 101.842 1.00 59.75  ? 170 GLY D O   1 
ATOM   9682  N N   . GLY D 1 225 ? 102.903 105.052 101.454 1.00 51.99  ? 171 GLY D N   1 
ATOM   9683  C CA  . GLY D 1 225 ? 101.918 105.064 102.524 1.00 55.46  ? 171 GLY D CA  1 
ATOM   9684  C C   . GLY D 1 225 ? 102.532 105.536 103.825 1.00 61.72  ? 171 GLY D C   1 
ATOM   9685  O O   . GLY D 1 225 ? 103.219 106.556 103.858 1.00 60.92  ? 171 GLY D O   1 
ATOM   9686  N N   . ASP D 1 226 ? 102.282 104.790 104.899 1.00 69.57  ? 172 ASP D N   1 
ATOM   9687  C CA  . ASP D 1 226 ? 102.842 105.117 106.203 1.00 72.35  ? 172 ASP D CA  1 
ATOM   9688  C C   . ASP D 1 226 ? 104.261 104.598 106.382 1.00 66.46  ? 172 ASP D C   1 
ATOM   9689  O O   . ASP D 1 226 ? 104.868 104.847 107.429 1.00 64.66  ? 172 ASP D O   1 
ATOM   9690  C CB  . ASP D 1 226 ? 101.943 104.569 107.315 1.00 75.85  ? 172 ASP D CB  1 
ATOM   9691  C CG  . ASP D 1 226 ? 100.646 105.346 107.451 1.00 82.57  ? 172 ASP D CG  1 
ATOM   9692  O OD1 . ASP D 1 226 ? 100.465 106.336 106.712 1.00 81.48  ? 172 ASP D OD1 1 
ATOM   9693  O OD2 . ASP D 1 226 ? 99.809  104.968 108.297 1.00 86.58  ? 172 ASP D OD2 1 
ATOM   9694  N N   . LYS D 1 227 ? 104.802 103.890 105.391 1.00 61.99  ? 173 LYS D N   1 
ATOM   9695  C CA  . LYS D 1 227 ? 106.186 103.443 105.403 1.00 61.42  ? 173 LYS D CA  1 
ATOM   9696  C C   . LYS D 1 227 ? 107.085 104.341 104.562 1.00 59.64  ? 173 LYS D C   1 
ATOM   9697  O O   . LYS D 1 227 ? 108.184 103.928 104.180 1.00 61.11  ? 173 LYS D O   1 
ATOM   9698  C CB  . LYS D 1 227 ? 106.278 101.999 104.911 1.00 67.34  ? 173 LYS D CB  1 
ATOM   9699  C CG  . LYS D 1 227 ? 105.374 101.032 105.652 1.00 71.11  ? 173 LYS D CG  1 
ATOM   9700  C CD  . LYS D 1 227 ? 105.374 99.668  104.986 1.00 79.55  ? 173 LYS D CD  1 
ATOM   9701  C CE  . LYS D 1 227 ? 104.347 98.742  105.614 1.00 82.08  ? 173 LYS D CE  1 
ATOM   9702  N NZ  . LYS D 1 227 ? 104.275 97.436  104.905 1.00 82.89  ? 173 LYS D NZ  1 
ATOM   9703  N N   . ALA D 1 228 ? 106.636 105.562 104.265 1.00 56.71  ? 174 ALA D N   1 
ATOM   9704  C CA  . ALA D 1 228 ? 107.414 106.462 103.424 1.00 52.90  ? 174 ALA D CA  1 
ATOM   9705  C C   . ALA D 1 228 ? 108.622 107.039 104.147 1.00 54.94  ? 174 ALA D C   1 
ATOM   9706  O O   . ALA D 1 228 ? 109.539 107.540 103.488 1.00 51.42  ? 174 ALA D O   1 
ATOM   9707  C CB  . ALA D 1 228 ? 106.527 107.592 102.909 1.00 52.66  ? 174 ALA D CB  1 
ATOM   9708  N N   . VAL D 1 229 ? 108.649 106.984 105.475 1.00 55.46  ? 175 VAL D N   1 
ATOM   9709  C CA  . VAL D 1 229 ? 109.773 107.470 106.264 1.00 52.48  ? 175 VAL D CA  1 
ATOM   9710  C C   . VAL D 1 229 ? 110.356 106.288 107.022 1.00 55.98  ? 175 VAL D C   1 
ATOM   9711  O O   . VAL D 1 229 ? 109.645 105.618 107.781 1.00 57.30  ? 175 VAL D O   1 
ATOM   9712  C CB  . VAL D 1 229 ? 109.357 108.594 107.225 1.00 50.21  ? 175 VAL D CB  1 
ATOM   9713  C CG1 . VAL D 1 229 ? 110.513 108.961 108.135 1.00 52.61  ? 175 VAL D CG1 1 
ATOM   9714  C CG2 . VAL D 1 229 ? 108.899 109.808 106.443 1.00 41.52  ? 175 VAL D CG2 1 
ATOM   9715  N N   . THR D 1 230 ? 111.645 106.034 106.818 1.00 53.52  ? 176 THR D N   1 
ATOM   9716  C CA  . THR D 1 230 ? 112.333 104.896 107.406 1.00 58.51  ? 176 THR D CA  1 
ATOM   9717  C C   . THR D 1 230 ? 113.495 105.376 108.267 1.00 59.43  ? 176 THR D C   1 
ATOM   9718  O O   . THR D 1 230 ? 113.851 106.556 108.275 1.00 57.89  ? 176 THR D O   1 
ATOM   9719  C CB  . THR D 1 230 ? 112.842 103.937 106.322 1.00 59.90  ? 176 THR D CB  1 
ATOM   9720  O OG1 . THR D 1 230 ? 113.866 104.580 105.555 1.00 65.76  ? 176 THR D OG1 1 
ATOM   9721  C CG2 . THR D 1 230 ? 111.707 103.530 105.395 1.00 54.36  ? 176 THR D CG2 1 
ATOM   9722  N N   . GLY D 1 231 ? 114.084 104.436 109.003 1.00 62.09  ? 177 GLY D N   1 
ATOM   9723  C CA  . GLY D 1 231 ? 115.227 104.736 109.838 1.00 63.48  ? 177 GLY D CA  1 
ATOM   9724  C C   . GLY D 1 231 ? 114.910 105.418 111.148 1.00 66.57  ? 177 GLY D C   1 
ATOM   9725  O O   . GLY D 1 231 ? 115.836 105.863 111.833 1.00 70.73  ? 177 GLY D O   1 
ATOM   9726  N N   . VAL D 1 232 ? 113.633 105.520 111.519 1.00 66.40  ? 178 VAL D N   1 
ATOM   9727  C CA  . VAL D 1 232 ? 113.279 106.199 112.761 1.00 68.78  ? 178 VAL D CA  1 
ATOM   9728  C C   . VAL D 1 232 ? 113.743 105.392 113.967 1.00 75.49  ? 178 VAL D C   1 
ATOM   9729  O O   . VAL D 1 232 ? 114.250 105.950 114.946 1.00 74.78  ? 178 VAL D O   1 
ATOM   9730  C CB  . VAL D 1 232 ? 111.765 106.471 112.806 1.00 63.47  ? 178 VAL D CB  1 
ATOM   9731  C CG1 . VAL D 1 232 ? 111.398 107.199 114.084 1.00 66.79  ? 178 VAL D CG1 1 
ATOM   9732  C CG2 . VAL D 1 232 ? 111.339 107.275 111.592 1.00 60.09  ? 178 VAL D CG2 1 
ATOM   9733  N N   . GLU D 1 233 ? 113.582 104.067 113.918 1.00 79.95  ? 179 GLU D N   1 
ATOM   9734  C CA  . GLU D 1 233 ? 113.984 103.224 115.039 1.00 81.38  ? 179 GLU D CA  1 
ATOM   9735  C C   . GLU D 1 233 ? 115.496 103.148 115.201 1.00 81.11  ? 179 GLU D C   1 
ATOM   9736  O O   . GLU D 1 233 ? 115.970 102.698 116.249 1.00 81.76  ? 179 GLU D O   1 
ATOM   9737  C CB  . GLU D 1 233 ? 113.414 101.813 114.877 1.00 82.12  ? 179 GLU D CB  1 
ATOM   9738  C CG  . GLU D 1 233 ? 114.039 101.011 113.747 1.00 87.14  ? 179 GLU D CG  1 
ATOM   9739  C CD  . GLU D 1 233 ? 113.539 101.434 112.380 1.00 88.53  ? 179 GLU D CD  1 
ATOM   9740  O OE1 . GLU D 1 233 ? 112.330 101.716 112.250 1.00 85.22  ? 179 GLU D OE1 1 
ATOM   9741  O OE2 . GLU D 1 233 ? 114.357 101.491 111.438 1.00 89.72  ? 179 GLU D OE2 1 
ATOM   9742  N N   . ARG D 1 234 ? 116.260 103.569 114.197 1.00 77.52  ? 180 ARG D N   1 
ATOM   9743  C CA  . ARG D 1 234 ? 117.714 103.555 114.267 1.00 79.00  ? 180 ARG D CA  1 
ATOM   9744  C C   . ARG D 1 234 ? 118.293 104.845 114.830 1.00 82.72  ? 180 ARG D C   1 
ATOM   9745  O O   . ARG D 1 234 ? 119.518 104.998 114.853 1.00 88.56  ? 180 ARG D O   1 
ATOM   9746  C CB  . ARG D 1 234 ? 118.311 103.300 112.881 1.00 81.19  ? 180 ARG D CB  1 
ATOM   9747  C CG  . ARG D 1 234 ? 117.925 101.973 112.257 1.00 82.83  ? 180 ARG D CG  1 
ATOM   9748  C CD  . ARG D 1 234 ? 118.690 101.729 110.960 1.00 86.61  ? 180 ARG D CD  1 
ATOM   9749  N NE  . ARG D 1 234 ? 118.362 102.700 109.922 1.00 94.72  ? 180 ARG D NE  1 
ATOM   9750  C CZ  . ARG D 1 234 ? 119.097 103.764 109.625 1.00 89.34  ? 180 ARG D CZ  1 
ATOM   9751  N NH1 . ARG D 1 234 ? 120.218 104.034 110.273 1.00 86.32  ? 180 ARG D NH1 1 
ATOM   9752  N NH2 . ARG D 1 234 ? 118.697 104.577 108.651 1.00 76.96  ? 180 ARG D NH2 1 
ATOM   9753  N N   . ILE D 1 235 ? 117.452 105.769 115.280 1.00 80.84  ? 181 ILE D N   1 
ATOM   9754  C CA  . ILE D 1 235 ? 117.918 107.072 115.739 1.00 83.20  ? 181 ILE D CA  1 
ATOM   9755  C C   . ILE D 1 235 ? 118.384 106.952 117.184 1.00 88.76  ? 181 ILE D C   1 
ATOM   9756  O O   . ILE D 1 235 ? 117.634 106.499 118.054 1.00 90.06  ? 181 ILE D O   1 
ATOM   9757  C CB  . ILE D 1 235 ? 116.817 108.130 115.595 1.00 76.71  ? 181 ILE D CB  1 
ATOM   9758  C CG1 . ILE D 1 235 ? 116.465 108.318 114.119 1.00 71.08  ? 181 ILE D CG1 1 
ATOM   9759  C CG2 . ILE D 1 235 ? 117.253 109.443 116.221 1.00 72.72  ? 181 ILE D CG2 1 
ATOM   9760  C CD1 . ILE D 1 235 ? 115.339 109.285 113.879 1.00 65.72  ? 181 ILE D CD1 1 
ATOM   9761  N N   . GLU D 1 236 ? 119.624 107.359 117.441 1.00 91.07  ? 182 GLU D N   1 
ATOM   9762  C CA  . GLU D 1 236 ? 120.224 107.304 118.772 1.00 91.90  ? 182 GLU D CA  1 
ATOM   9763  C C   . GLU D 1 236 ? 120.343 108.725 119.311 1.00 90.49  ? 182 GLU D C   1 
ATOM   9764  O O   . GLU D 1 236 ? 121.280 109.452 118.970 1.00 89.31  ? 182 GLU D O   1 
ATOM   9765  C CB  . GLU D 1 236 ? 121.586 106.617 118.733 1.00 96.64  ? 182 GLU D CB  1 
ATOM   9766  C CG  . GLU D 1 236 ? 121.531 105.108 118.601 1.00 103.44 ? 182 GLU D CG  1 
ATOM   9767  C CD  . GLU D 1 236 ? 122.910 104.476 118.636 1.00 117.24 ? 182 GLU D CD  1 
ATOM   9768  O OE1 . GLU D 1 236 ? 123.902 105.202 118.412 1.00 113.40 ? 182 GLU D OE1 1 
ATOM   9769  O OE2 . GLU D 1 236 ? 123.002 103.258 118.894 1.00 124.53 ? 182 GLU D OE2 1 
ATOM   9770  N N   . LEU D 1 237 ? 119.392 109.114 120.156 1.00 85.57  ? 183 LEU D N   1 
ATOM   9771  C CA  . LEU D 1 237 ? 119.451 110.384 120.864 1.00 80.55  ? 183 LEU D CA  1 
ATOM   9772  C C   . LEU D 1 237 ? 119.812 110.126 122.317 1.00 78.32  ? 183 LEU D C   1 
ATOM   9773  O O   . LEU D 1 237 ? 119.076 109.406 123.009 1.00 76.72  ? 183 LEU D O   1 
ATOM   9774  C CB  . LEU D 1 237 ? 118.121 111.128 120.766 1.00 78.56  ? 183 LEU D CB  1 
ATOM   9775  C CG  . LEU D 1 237 ? 117.924 111.979 119.512 1.00 71.46  ? 183 LEU D CG  1 
ATOM   9776  C CD1 . LEU D 1 237 ? 116.535 112.589 119.491 1.00 66.84  ? 183 LEU D CD1 1 
ATOM   9777  C CD2 . LEU D 1 237 ? 118.984 113.063 119.450 1.00 61.50  ? 183 LEU D CD2 1 
ATOM   9778  N N   . PRO D 1 238 ? 120.930 110.663 122.811 1.00 82.75  ? 184 PRO D N   1 
ATOM   9779  C CA  . PRO D 1 238 ? 121.327 110.374 124.201 1.00 81.42  ? 184 PRO D CA  1 
ATOM   9780  C C   . PRO D 1 238 ? 120.289 110.780 125.233 1.00 82.24  ? 184 PRO D C   1 
ATOM   9781  O O   . PRO D 1 238 ? 120.110 110.074 126.232 1.00 86.34  ? 184 PRO D O   1 
ATOM   9782  C CB  . PRO D 1 238 ? 122.629 111.173 124.362 1.00 83.83  ? 184 PRO D CB  1 
ATOM   9783  C CG  . PRO D 1 238 ? 123.135 111.368 122.969 1.00 85.01  ? 184 PRO D CG  1 
ATOM   9784  C CD  . PRO D 1 238 ? 121.912 111.512 122.118 1.00 84.77  ? 184 PRO D CD  1 
ATOM   9785  N N   . GLN D 1 239 ? 119.594 111.897 125.020 1.00 78.58  ? 185 GLN D N   1 
ATOM   9786  C CA  . GLN D 1 239 ? 118.655 112.418 126.002 1.00 73.62  ? 185 GLN D CA  1 
ATOM   9787  C C   . GLN D 1 239 ? 117.195 112.192 125.632 1.00 71.45  ? 185 GLN D C   1 
ATOM   9788  O O   . GLN D 1 239 ? 116.315 112.506 126.441 1.00 72.64  ? 185 GLN D O   1 
ATOM   9789  C CB  . GLN D 1 239 ? 118.899 113.920 126.214 1.00 74.61  ? 185 GLN D CB  1 
ATOM   9790  C CG  . GLN D 1 239 ? 118.353 114.476 127.520 1.00 74.62  ? 185 GLN D CG  1 
ATOM   9791  C CD  . GLN D 1 239 ? 118.448 115.985 127.596 1.00 75.23  ? 185 GLN D CD  1 
ATOM   9792  O OE1 . GLN D 1 239 ? 117.707 116.628 128.340 1.00 70.44  ? 185 GLN D OE1 1 
ATOM   9793  N NE2 . GLN D 1 239 ? 119.362 116.561 126.825 1.00 77.33  ? 185 GLN D NE2 1 
ATOM   9794  N N   . PHE D 1 240 ? 116.909 111.644 124.455 1.00 71.40  ? 186 PHE D N   1 
ATOM   9795  C CA  . PHE D 1 240 ? 115.539 111.507 123.989 1.00 70.62  ? 186 PHE D CA  1 
ATOM   9796  C C   . PHE D 1 240 ? 115.303 110.116 123.420 1.00 74.21  ? 186 PHE D C   1 
ATOM   9797  O O   . PHE D 1 240 ? 116.228 109.437 122.968 1.00 78.48  ? 186 PHE D O   1 
ATOM   9798  C CB  . PHE D 1 240 ? 115.197 112.557 122.925 1.00 70.81  ? 186 PHE D CB  1 
ATOM   9799  C CG  . PHE D 1 240 ? 115.083 113.949 123.464 1.00 70.99  ? 186 PHE D CG  1 
ATOM   9800  C CD1 . PHE D 1 240 ? 113.890 114.400 123.995 1.00 68.75  ? 186 PHE D CD1 1 
ATOM   9801  C CD2 . PHE D 1 240 ? 116.167 114.807 123.436 1.00 69.35  ? 186 PHE D CD2 1 
ATOM   9802  C CE1 . PHE D 1 240 ? 113.779 115.679 124.491 1.00 71.95  ? 186 PHE D CE1 1 
ATOM   9803  C CE2 . PHE D 1 240 ? 116.062 116.087 123.930 1.00 68.46  ? 186 PHE D CE2 1 
ATOM   9804  C CZ  . PHE D 1 240 ? 114.866 116.525 124.457 1.00 72.87  ? 186 PHE D CZ  1 
ATOM   9805  N N   . SER D 1 241 ? 114.037 109.708 123.449 1.00 74.53  ? 187 SER D N   1 
ATOM   9806  C CA  . SER D 1 241 ? 113.579 108.471 122.839 1.00 74.70  ? 187 SER D CA  1 
ATOM   9807  C C   . SER D 1 241 ? 112.338 108.768 122.012 1.00 75.59  ? 187 SER D C   1 
ATOM   9808  O O   . SER D 1 241 ? 111.432 109.468 122.473 1.00 77.91  ? 187 SER D O   1 
ATOM   9809  C CB  . SER D 1 241 ? 113.272 107.406 123.897 1.00 75.28  ? 187 SER D CB  1 
ATOM   9810  O OG  . SER D 1 241 ? 112.277 107.858 124.799 1.00 82.01  ? 187 SER D OG  1 
ATOM   9811  N N   . ILE D 1 242 ? 112.298 108.235 120.794 1.00 73.91  ? 188 ILE D N   1 
ATOM   9812  C CA  . ILE D 1 242 ? 111.237 108.546 119.841 1.00 73.74  ? 188 ILE D CA  1 
ATOM   9813  C C   . ILE D 1 242 ? 110.092 107.568 120.084 1.00 75.30  ? 188 ILE D C   1 
ATOM   9814  O O   . ILE D 1 242 ? 110.149 106.407 119.676 1.00 78.15  ? 188 ILE D O   1 
ATOM   9815  C CB  . ILE D 1 242 ? 111.738 108.489 118.399 1.00 72.78  ? 188 ILE D CB  1 
ATOM   9816  C CG1 . ILE D 1 242 ? 112.965 109.383 118.241 1.00 74.37  ? 188 ILE D CG1 1 
ATOM   9817  C CG2 . ILE D 1 242 ? 110.641 108.915 117.438 1.00 69.69  ? 188 ILE D CG2 1 
ATOM   9818  C CD1 . ILE D 1 242 ? 113.387 109.588 116.817 1.00 82.11  ? 188 ILE D CD1 1 
ATOM   9819  N N   . VAL D 1 243 ? 109.045 108.046 120.758 1.00 74.23  ? 189 VAL D N   1 
ATOM   9820  C CA  . VAL D 1 243 ? 107.904 107.192 121.069 1.00 71.99  ? 189 VAL D CA  1 
ATOM   9821  C C   . VAL D 1 243 ? 107.103 106.874 119.811 1.00 75.29  ? 189 VAL D C   1 
ATOM   9822  O O   . VAL D 1 243 ? 106.724 105.721 119.578 1.00 79.55  ? 189 VAL D O   1 
ATOM   9823  C CB  . VAL D 1 243 ? 107.025 107.853 122.145 1.00 73.92  ? 189 VAL D CB  1 
ATOM   9824  C CG1 . VAL D 1 243 ? 105.849 106.956 122.493 1.00 77.26  ? 189 VAL D CG1 1 
ATOM   9825  C CG2 . VAL D 1 243 ? 107.850 108.161 123.380 1.00 77.86  ? 189 VAL D CG2 1 
ATOM   9826  N N   . GLU D 1 244 ? 106.834 107.880 118.982 1.00 74.20  ? 190 GLU D N   1 
ATOM   9827  C CA  . GLU D 1 244 ? 105.975 107.682 117.825 1.00 72.11  ? 190 GLU D CA  1 
ATOM   9828  C C   . GLU D 1 244 ? 106.303 108.718 116.759 1.00 71.78  ? 190 GLU D C   1 
ATOM   9829  O O   . GLU D 1 244 ? 106.868 109.778 117.043 1.00 76.59  ? 190 GLU D O   1 
ATOM   9830  C CB  . GLU D 1 244 ? 104.493 107.769 118.214 1.00 75.68  ? 190 GLU D CB  1 
ATOM   9831  C CG  . GLU D 1 244 ? 103.526 107.290 117.143 1.00 80.00  ? 190 GLU D CG  1 
ATOM   9832  C CD  . GLU D 1 244 ? 102.105 107.747 117.396 1.00 87.14  ? 190 GLU D CD  1 
ATOM   9833  O OE1 . GLU D 1 244 ? 101.894 108.539 118.338 1.00 93.54  ? 190 GLU D OE1 1 
ATOM   9834  O OE2 . GLU D 1 244 ? 101.199 107.316 116.652 1.00 88.82  ? 190 GLU D OE2 1 
ATOM   9835  N N   . HIS D 1 245 ? 105.946 108.387 115.518 1.00 68.88  ? 191 HIS D N   1 
ATOM   9836  C CA  . HIS D 1 245 ? 106.027 109.319 114.406 1.00 63.30  ? 191 HIS D CA  1 
ATOM   9837  C C   . HIS D 1 245 ? 104.805 109.141 113.517 1.00 62.96  ? 191 HIS D C   1 
ATOM   9838  O O   . HIS D 1 245 ? 104.269 108.038 113.379 1.00 65.10  ? 191 HIS D O   1 
ATOM   9839  C CB  . HIS D 1 245 ? 107.318 109.132 113.595 1.00 57.58  ? 191 HIS D CB  1 
ATOM   9840  C CG  . HIS D 1 245 ? 107.306 107.937 112.695 1.00 58.91  ? 191 HIS D CG  1 
ATOM   9841  N ND1 . HIS D 1 245 ? 107.742 106.694 113.099 1.00 63.57  ? 191 HIS D ND1 1 
ATOM   9842  C CD2 . HIS D 1 245 ? 106.922 107.799 111.404 1.00 58.13  ? 191 HIS D CD2 1 
ATOM   9843  C CE1 . HIS D 1 245 ? 107.622 105.841 112.098 1.00 64.53  ? 191 HIS D CE1 1 
ATOM   9844  N NE2 . HIS D 1 245 ? 107.126 106.485 111.058 1.00 63.19  ? 191 HIS D NE2 1 
ATOM   9845  N N   . ARG D 1 246 ? 104.370 110.245 112.917 1.00 59.20  ? 192 ARG D N   1 
ATOM   9846  C CA  . ARG D 1 246 ? 103.173 110.276 112.091 1.00 56.60  ? 192 ARG D CA  1 
ATOM   9847  C C   . ARG D 1 246 ? 103.444 110.998 110.781 1.00 55.59  ? 192 ARG D C   1 
ATOM   9848  O O   . ARG D 1 246 ? 104.265 111.919 110.715 1.00 59.43  ? 192 ARG D O   1 
ATOM   9849  C CB  . ARG D 1 246 ? 102.008 110.961 112.810 1.00 62.78  ? 192 ARG D CB  1 
ATOM   9850  C CG  . ARG D 1 246 ? 101.395 110.147 113.928 1.00 78.77  ? 192 ARG D CG  1 
ATOM   9851  C CD  . ARG D 1 246 ? 100.265 110.914 114.583 1.00 84.42  ? 192 ARG D CD  1 
ATOM   9852  N NE  . ARG D 1 246 ? 99.645  110.167 115.669 1.00 86.44  ? 192 ARG D NE  1 
ATOM   9853  C CZ  . ARG D 1 246 ? 98.780  110.685 116.529 1.00 92.97  ? 192 ARG D CZ  1 
ATOM   9854  N NH1 . ARG D 1 246 ? 98.423  111.957 116.468 1.00 96.59  ? 192 ARG D NH1 1 
ATOM   9855  N NH2 . ARG D 1 246 ? 98.263  109.908 117.477 1.00 93.86  ? 192 ARG D NH2 1 
ATOM   9856  N N   . LEU D 1 247 ? 102.729 110.570 109.742 1.00 53.81  ? 193 LEU D N   1 
ATOM   9857  C CA  . LEU D 1 247 ? 102.778 111.175 108.418 1.00 50.75  ? 193 LEU D CA  1 
ATOM   9858  C C   . LEU D 1 247 ? 101.410 111.749 108.086 1.00 53.36  ? 193 LEU D C   1 
ATOM   9859  O O   . LEU D 1 247 ? 100.399 111.046 108.183 1.00 61.16  ? 193 LEU D O   1 
ATOM   9860  C CB  . LEU D 1 247 ? 103.184 110.151 107.358 1.00 49.04  ? 193 LEU D CB  1 
ATOM   9861  C CG  . LEU D 1 247 ? 104.473 109.375 107.608 1.00 49.18  ? 193 LEU D CG  1 
ATOM   9862  C CD1 . LEU D 1 247 ? 104.794 108.481 106.426 1.00 49.90  ? 193 LEU D CD1 1 
ATOM   9863  C CD2 . LEU D 1 247 ? 105.603 110.340 107.870 1.00 46.31  ? 193 LEU D CD2 1 
ATOM   9864  N N   . VAL D 1 248 ? 101.376 113.019 107.689 1.00 49.36  ? 194 VAL D N   1 
ATOM   9865  C CA  . VAL D 1 248 ? 100.135 113.712 107.369 1.00 49.88  ? 194 VAL D CA  1 
ATOM   9866  C C   . VAL D 1 248 ? 100.265 114.333 105.987 1.00 54.58  ? 194 VAL D C   1 
ATOM   9867  O O   . VAL D 1 248 ? 101.329 114.843 105.627 1.00 57.09  ? 194 VAL D O   1 
ATOM   9868  C CB  . VAL D 1 248 ? 99.798  114.790 108.422 1.00 53.33  ? 194 VAL D CB  1 
ATOM   9869  C CG1 . VAL D 1 248 ? 98.423  115.381 108.164 1.00 64.64  ? 194 VAL D CG1 1 
ATOM   9870  C CG2 . VAL D 1 248 ? 99.877  114.213 109.825 1.00 63.47  ? 194 VAL D CG2 1 
ATOM   9871  N N   . SER D 1 249 ? 99.185  114.288 105.211 1.00 55.95  ? 195 SER D N   1 
ATOM   9872  C CA  . SER D 1 249 ? 99.132  114.924 103.900 1.00 54.11  ? 195 SER D CA  1 
ATOM   9873  C C   . SER D 1 249 ? 97.853  115.739 103.803 1.00 61.45  ? 195 SER D C   1 
ATOM   9874  O O   . SER D 1 249 ? 96.772  115.234 104.118 1.00 77.36  ? 195 SER D O   1 
ATOM   9875  C CB  . SER D 1 249 ? 99.184  113.885 102.776 1.00 57.55  ? 195 SER D CB  1 
ATOM   9876  O OG  . SER D 1 249 ? 99.097  114.507 101.506 1.00 63.61  ? 195 SER D OG  1 
ATOM   9877  N N   . ARG D 1 250 ? 97.969  116.989 103.360 1.00 55.25  ? 196 ARG D N   1 
ATOM   9878  C CA  . ARG D 1 250 ? 96.803  117.864 103.294 1.00 59.87  ? 196 ARG D CA  1 
ATOM   9879  C C   . ARG D 1 250 ? 97.100  119.033 102.363 1.00 61.71  ? 196 ARG D C   1 
ATOM   9880  O O   . ARG D 1 250 ? 98.138  119.082 101.700 1.00 67.74  ? 196 ARG D O   1 
ATOM   9881  C CB  . ARG D 1 250 ? 96.405  118.352 104.688 1.00 64.17  ? 196 ARG D CB  1 
ATOM   9882  C CG  . ARG D 1 250 ? 97.452  119.218 105.361 1.00 59.11  ? 196 ARG D CG  1 
ATOM   9883  C CD  . ARG D 1 250 ? 97.106  119.457 106.817 1.00 66.86  ? 196 ARG D CD  1 
ATOM   9884  N NE  . ARG D 1 250 ? 97.945  120.484 107.420 1.00 68.69  ? 196 ARG D NE  1 
ATOM   9885  C CZ  . ARG D 1 250 ? 97.592  121.755 107.547 1.00 70.71  ? 196 ARG D CZ  1 
ATOM   9886  N NH1 . ARG D 1 250 ? 96.420  122.193 107.117 1.00 68.86  ? 196 ARG D NH1 1 
ATOM   9887  N NH2 . ARG D 1 250 ? 98.434  122.608 108.125 1.00 71.07  ? 196 ARG D NH2 1 
ATOM   9888  N N   . ASN D 1 251 ? 96.156  119.971 102.307 1.00 59.96  ? 197 ASN D N   1 
ATOM   9889  C CA  . ASN D 1 251 ? 96.280  121.200 101.536 1.00 59.29  ? 197 ASN D CA  1 
ATOM   9890  C C   . ASN D 1 251 ? 96.053  122.391 102.454 1.00 68.53  ? 197 ASN D C   1 
ATOM   9891  O O   . ASN D 1 251 ? 95.166  122.363 103.313 1.00 75.53  ? 197 ASN D O   1 
ATOM   9892  C CB  . ASN D 1 251 ? 95.273  121.244 100.382 1.00 57.91  ? 197 ASN D CB  1 
ATOM   9893  C CG  . ASN D 1 251 ? 95.555  120.205 99.316  1.00 64.40  ? 197 ASN D CG  1 
ATOM   9894  O OD1 . ASN D 1 251 ? 96.395  119.326 99.495  1.00 65.49  ? 197 ASN D OD1 1 
ATOM   9895  N ND2 . ASN D 1 251 ? 94.847  120.300 98.198  1.00 68.28  ? 197 ASN D ND2 1 
ATOM   9896  N N   . VAL D 1 252 ? 96.851  123.438 102.270 1.00 67.15  ? 198 VAL D N   1 
ATOM   9897  C CA  . VAL D 1 252 ? 96.753  124.660 103.059 1.00 67.12  ? 198 VAL D CA  1 
ATOM   9898  C C   . VAL D 1 252 ? 96.341  125.794 102.134 1.00 73.91  ? 198 VAL D C   1 
ATOM   9899  O O   . VAL D 1 252 ? 96.945  125.989 101.074 1.00 77.87  ? 198 VAL D O   1 
ATOM   9900  C CB  . VAL D 1 252 ? 98.076  124.977 103.777 1.00 67.24  ? 198 VAL D CB  1 
ATOM   9901  C CG1 . VAL D 1 252 ? 98.238  124.085 104.990 1.00 65.17  ? 198 VAL D CG1 1 
ATOM   9902  C CG2 . VAL D 1 252 ? 99.250  124.788 102.833 1.00 70.78  ? 198 VAL D CG2 1 
ATOM   9903  N N   . VAL D 1 253 ? 95.309  126.536 102.526 1.00 76.31  ? 199 VAL D N   1 
ATOM   9904  C CA  . VAL D 1 253 ? 94.740  127.583 101.683 1.00 81.76  ? 199 VAL D CA  1 
ATOM   9905  C C   . VAL D 1 253 ? 95.383  128.906 102.086 1.00 86.58  ? 199 VAL D C   1 
ATOM   9906  O O   . VAL D 1 253 ? 95.019  129.506 103.098 1.00 88.96  ? 199 VAL D O   1 
ATOM   9907  C CB  . VAL D 1 253 ? 93.216  127.633 101.799 1.00 79.00  ? 199 VAL D CB  1 
ATOM   9908  C CG1 . VAL D 1 253 ? 92.644  128.666 100.840 1.00 74.35  ? 199 VAL D CG1 1 
ATOM   9909  C CG2 . VAL D 1 253 ? 92.622  126.260 101.529 1.00 70.21  ? 199 VAL D CG2 1 
ATOM   9910  N N   . PHE D 1 254 ? 96.347  129.362 101.290 1.00 89.22  ? 200 PHE D N   1 
ATOM   9911  C CA  . PHE D 1 254 ? 96.941  130.677 101.447 1.00 93.57  ? 200 PHE D CA  1 
ATOM   9912  C C   . PHE D 1 254 ? 96.292  131.644 100.460 1.00 96.05  ? 200 PHE D C   1 
ATOM   9913  O O   . PHE D 1 254 ? 95.454  131.264 99.637  1.00 95.23  ? 200 PHE D O   1 
ATOM   9914  C CB  . PHE D 1 254 ? 98.457  130.612 101.246 1.00 92.98  ? 200 PHE D CB  1 
ATOM   9915  C CG  . PHE D 1 254 ? 99.204  130.083 102.436 1.00 102.06 ? 200 PHE D CG  1 
ATOM   9916  C CD1 . PHE D 1 254 ? 99.188  128.731 102.737 1.00 96.87  ? 200 PHE D CD1 1 
ATOM   9917  C CD2 . PHE D 1 254 ? 99.930  130.937 103.249 1.00 104.45 ? 200 PHE D CD2 1 
ATOM   9918  C CE1 . PHE D 1 254 ? 99.877  128.242 103.832 1.00 93.78  ? 200 PHE D CE1 1 
ATOM   9919  C CE2 . PHE D 1 254 ? 100.622 130.454 104.344 1.00 106.33 ? 200 PHE D CE2 1 
ATOM   9920  C CZ  . PHE D 1 254 ? 100.595 129.105 104.635 1.00 102.29 ? 200 PHE D CZ  1 
ATOM   9921  N N   . ALA D 1 255 ? 96.707  132.912 100.537 1.00 98.62  ? 201 ALA D N   1 
ATOM   9922  C CA  . ALA D 1 255 ? 96.085  133.955 99.726  1.00 100.75 ? 201 ALA D CA  1 
ATOM   9923  C C   . ALA D 1 255 ? 96.110  133.603 98.244  1.00 100.39 ? 201 ALA D C   1 
ATOM   9924  O O   . ALA D 1 255 ? 95.150  133.882 97.516  1.00 99.62  ? 201 ALA D O   1 
ATOM   9925  C CB  . ALA D 1 255 ? 96.780  135.294 99.971  1.00 97.22  ? 201 ALA D CB  1 
ATOM   9926  N N   . THR D 1 256 ? 97.192  132.986 97.778  1.00 100.09 ? 202 THR D N   1 
ATOM   9927  C CA  . THR D 1 256 ? 97.281  132.540 96.388  1.00 103.23 ? 202 THR D CA  1 
ATOM   9928  C C   . THR D 1 256 ? 96.823  131.091 96.232  1.00 97.85  ? 202 THR D C   1 
ATOM   9929  O O   . THR D 1 256 ? 97.521  130.259 95.655  1.00 92.88  ? 202 THR D O   1 
ATOM   9930  C CB  . THR D 1 256 ? 98.702  132.722 95.868  1.00 101.51 ? 202 THR D CB  1 
ATOM   9931  O OG1 . THR D 1 256 ? 99.615  131.984 96.690  1.00 100.63 ? 202 THR D OG1 1 
ATOM   9932  C CG2 . THR D 1 256 ? 99.091  134.194 95.882  1.00 97.11  ? 202 THR D CG2 1 
ATOM   9933  N N   . GLY D 1 257 ? 95.634  130.780 96.746  1.00 94.86  ? 203 GLY D N   1 
ATOM   9934  C CA  . GLY D 1 257 ? 95.053  129.470 96.540  1.00 87.36  ? 203 GLY D CA  1 
ATOM   9935  C C   . GLY D 1 257 ? 95.609  128.411 97.474  1.00 86.64  ? 203 GLY D C   1 
ATOM   9936  O O   . GLY D 1 257 ? 96.247  128.692 98.489  1.00 90.80  ? 203 GLY D O   1 
ATOM   9937  N N   . ALA D 1 258 ? 95.340  127.160 97.117  1.00 78.01  ? 204 ALA D N   1 
ATOM   9938  C CA  . ALA D 1 258 ? 95.760  126.028 97.927  1.00 69.63  ? 204 ALA D CA  1 
ATOM   9939  C C   . ALA D 1 258 ? 97.166  125.580 97.550  1.00 64.37  ? 204 ALA D C   1 
ATOM   9940  O O   . ALA D 1 258 ? 97.601  125.718 96.404  1.00 67.38  ? 204 ALA D O   1 
ATOM   9941  C CB  . ALA D 1 258 ? 94.781  124.864 97.777  1.00 63.06  ? 204 ALA D CB  1 
ATOM   9942  N N   . TYR D 1 259 ? 97.876  125.039 98.538  1.00 61.22  ? 205 TYR D N   1 
ATOM   9943  C CA  . TYR D 1 259 ? 99.222  124.518 98.388  1.00 57.75  ? 205 TYR D CA  1 
ATOM   9944  C C   . TYR D 1 259 ? 99.307  123.145 99.040  1.00 59.66  ? 205 TYR D C   1 
ATOM   9945  O O   . TYR D 1 259 ? 98.745  122.936 100.122 1.00 62.83  ? 205 TYR D O   1 
ATOM   9946  C CB  . TYR D 1 259 ? 100.255 125.457 99.031  1.00 58.85  ? 205 TYR D CB  1 
ATOM   9947  C CG  . TYR D 1 259 ? 100.548 126.712 98.238  1.00 65.12  ? 205 TYR D CG  1 
ATOM   9948  C CD1 . TYR D 1 259 ? 99.681  127.795 98.265  1.00 74.64  ? 205 TYR D CD1 1 
ATOM   9949  C CD2 . TYR D 1 259 ? 101.702 126.816 97.474  1.00 64.46  ? 205 TYR D CD2 1 
ATOM   9950  C CE1 . TYR D 1 259 ? 99.951  128.945 97.542  1.00 74.09  ? 205 TYR D CE1 1 
ATOM   9951  C CE2 . TYR D 1 259 ? 101.979 127.961 96.750  1.00 64.16  ? 205 TYR D CE2 1 
ATOM   9952  C CZ  . TYR D 1 259 ? 101.101 129.022 96.788  1.00 67.90  ? 205 TYR D CZ  1 
ATOM   9953  O OH  . TYR D 1 259 ? 101.375 130.162 96.069  1.00 67.80  ? 205 TYR D OH  1 
ATOM   9954  N N   . PRO D 1 260 ? 99.994  122.193 98.413  1.00 53.40  ? 206 PRO D N   1 
ATOM   9955  C CA  . PRO D 1 260 ? 100.161 120.875 99.032  1.00 50.57  ? 206 PRO D CA  1 
ATOM   9956  C C   . PRO D 1 260 ? 101.036 120.954 100.272 1.00 50.57  ? 206 PRO D C   1 
ATOM   9957  O O   . PRO D 1 260 ? 101.892 121.832 100.401 1.00 56.49  ? 206 PRO D O   1 
ATOM   9958  C CB  . PRO D 1 260 ? 100.833 120.050 97.931  1.00 49.73  ? 206 PRO D CB  1 
ATOM   9959  C CG  . PRO D 1 260 ? 101.551 121.063 97.106  1.00 50.42  ? 206 PRO D CG  1 
ATOM   9960  C CD  . PRO D 1 260 ? 100.672 122.280 97.109  1.00 51.47  ? 206 PRO D CD  1 
ATOM   9961  N N   . ARG D 1 261 ? 100.820 120.016 101.191 1.00 45.70  ? 207 ARG D N   1 
ATOM   9962  C CA  . ARG D 1 261 ? 101.554 120.008 102.447 1.00 47.95  ? 207 ARG D CA  1 
ATOM   9963  C C   . ARG D 1 261 ? 101.738 118.578 102.923 1.00 50.91  ? 207 ARG D C   1 
ATOM   9964  O O   . ARG D 1 261 ? 100.766 117.819 103.008 1.00 56.82  ? 207 ARG D O   1 
ATOM   9965  C CB  . ARG D 1 261 ? 100.817 120.821 103.515 1.00 55.39  ? 207 ARG D CB  1 
ATOM   9966  C CG  . ARG D 1 261 ? 101.382 120.655 104.912 1.00 55.80  ? 207 ARG D CG  1 
ATOM   9967  C CD  . ARG D 1 261 ? 102.612 121.513 105.109 1.00 57.38  ? 207 ARG D CD  1 
ATOM   9968  N NE  . ARG D 1 261 ? 102.269 122.927 105.188 1.00 62.67  ? 207 ARG D NE  1 
ATOM   9969  C CZ  . ARG D 1 261 ? 101.842 123.529 106.289 1.00 63.87  ? 207 ARG D CZ  1 
ATOM   9970  N NH1 . ARG D 1 261 ? 101.687 122.865 107.423 1.00 59.60  ? 207 ARG D NH1 1 
ATOM   9971  N NH2 . ARG D 1 261 ? 101.562 124.828 106.251 1.00 68.42  ? 207 ARG D NH2 1 
ATOM   9972  N N   . LEU D 1 262 ? 102.981 118.220 103.232 1.00 46.10  ? 208 LEU D N   1 
ATOM   9973  C CA  . LEU D 1 262 ? 103.302 116.975 103.908 1.00 43.29  ? 208 LEU D CA  1 
ATOM   9974  C C   . LEU D 1 262 ? 103.897 117.304 105.269 1.00 45.81  ? 208 LEU D C   1 
ATOM   9975  O O   . LEU D 1 262 ? 104.594 118.305 105.429 1.00 49.97  ? 208 LEU D O   1 
ATOM   9976  C CB  . LEU D 1 262 ? 104.285 116.127 103.098 1.00 39.06  ? 208 LEU D CB  1 
ATOM   9977  C CG  . LEU D 1 262 ? 103.849 115.731 101.688 1.00 43.20  ? 208 LEU D CG  1 
ATOM   9978  C CD1 . LEU D 1 262 ? 104.883 114.820 101.056 1.00 43.14  ? 208 LEU D CD1 1 
ATOM   9979  C CD2 . LEU D 1 262 ? 102.488 115.061 101.714 1.00 42.99  ? 208 LEU D CD2 1 
ATOM   9980  N N   . SER D 1 263 ? 103.603 116.469 106.255 1.00 44.03  ? 209 SER D N   1 
ATOM   9981  C CA  . SER D 1 263 ? 104.074 116.714 107.608 1.00 42.06  ? 209 SER D CA  1 
ATOM   9982  C C   . SER D 1 263 ? 104.582 115.415 108.201 1.00 42.37  ? 209 SER D C   1 
ATOM   9983  O O   . SER D 1 263 ? 103.888 114.396 108.157 1.00 47.99  ? 209 SER D O   1 
ATOM   9984  C CB  . SER D 1 263 ? 102.961 117.302 108.481 1.00 45.82  ? 209 SER D CB  1 
ATOM   9985  O OG  . SER D 1 263 ? 102.475 118.514 107.931 1.00 51.22  ? 209 SER D OG  1 
ATOM   9986  N N   . LEU D 1 264 ? 105.789 115.456 108.753 1.00 42.00  ? 210 LEU D N   1 
ATOM   9987  C CA  . LEU D 1 264 ? 106.368 114.323 109.461 1.00 46.84  ? 210 LEU D CA  1 
ATOM   9988  C C   . LEU D 1 264 ? 106.589 114.745 110.904 1.00 53.06  ? 210 LEU D C   1 
ATOM   9989  O O   . LEU D 1 264 ? 107.359 115.671 111.168 1.00 59.62  ? 210 LEU D O   1 
ATOM   9990  C CB  . LEU D 1 264 ? 107.677 113.880 108.807 1.00 41.50  ? 210 LEU D CB  1 
ATOM   9991  C CG  . LEU D 1 264 ? 108.639 113.014 109.618 1.00 45.29  ? 210 LEU D CG  1 
ATOM   9992  C CD1 . LEU D 1 264 ? 107.967 111.749 110.119 1.00 50.01  ? 210 LEU D CD1 1 
ATOM   9993  C CD2 . LEU D 1 264 ? 109.856 112.675 108.778 1.00 48.60  ? 210 LEU D CD2 1 
ATOM   9994  N N   . SER D 1 265 ? 105.919 114.072 111.833 1.00 49.42  ? 211 SER D N   1 
ATOM   9995  C CA  . SER D 1 265 ? 105.919 114.474 113.232 1.00 52.84  ? 211 SER D CA  1 
ATOM   9996  C C   . SER D 1 265 ? 106.549 113.383 114.081 1.00 57.76  ? 211 SER D C   1 
ATOM   9997  O O   . SER D 1 265 ? 106.225 112.206 113.917 1.00 64.94  ? 211 SER D O   1 
ATOM   9998  C CB  . SER D 1 265 ? 104.497 114.758 113.717 1.00 62.36  ? 211 SER D CB  1 
ATOM   9999  O OG  . SER D 1 265 ? 103.857 115.714 112.892 1.00 70.32  ? 211 SER D OG  1 
ATOM   10000 N N   . PHE D 1 266 ? 107.443 113.776 114.986 1.00 56.36  ? 212 PHE D N   1 
ATOM   10001 C CA  . PHE D 1 266 ? 108.021 112.873 115.966 1.00 56.82  ? 212 PHE D CA  1 
ATOM   10002 C C   . PHE D 1 266 ? 107.619 113.327 117.360 1.00 63.18  ? 212 PHE D C   1 
ATOM   10003 O O   . PHE D 1 266 ? 107.438 114.523 117.612 1.00 70.64  ? 212 PHE D O   1 
ATOM   10004 C CB  . PHE D 1 266 ? 109.553 112.832 115.888 1.00 60.53  ? 212 PHE D CB  1 
ATOM   10005 C CG  . PHE D 1 266 ? 110.107 113.061 114.515 1.00 61.50  ? 212 PHE D CG  1 
ATOM   10006 C CD1 . PHE D 1 266 ? 110.319 112.001 113.653 1.00 61.11  ? 212 PHE D CD1 1 
ATOM   10007 C CD2 . PHE D 1 266 ? 110.440 114.338 114.095 1.00 61.76  ? 212 PHE D CD2 1 
ATOM   10008 C CE1 . PHE D 1 266 ? 110.837 112.210 112.394 1.00 62.87  ? 212 PHE D CE1 1 
ATOM   10009 C CE2 . PHE D 1 266 ? 110.958 114.554 112.836 1.00 64.04  ? 212 PHE D CE2 1 
ATOM   10010 C CZ  . PHE D 1 266 ? 111.159 113.489 111.986 1.00 60.85  ? 212 PHE D CZ  1 
ATOM   10011 N N   . ARG D 1 267 ? 107.483 112.363 118.267 1.00 66.44  ? 213 ARG D N   1 
ATOM   10012 C CA  . ARG D 1 267 ? 107.275 112.647 119.680 1.00 67.85  ? 213 ARG D CA  1 
ATOM   10013 C C   . ARG D 1 267 ? 108.466 112.115 120.462 1.00 66.69  ? 213 ARG D C   1 
ATOM   10014 O O   . ARG D 1 267 ? 108.826 110.941 120.329 1.00 72.14  ? 213 ARG D O   1 
ATOM   10015 C CB  . ARG D 1 267 ? 105.967 112.034 120.186 1.00 70.23  ? 213 ARG D CB  1 
ATOM   10016 C CG  . ARG D 1 267 ? 105.425 112.714 121.432 1.00 73.07  ? 213 ARG D CG  1 
ATOM   10017 C CD  . ARG D 1 267 ? 103.907 112.631 121.516 1.00 78.36  ? 213 ARG D CD  1 
ATOM   10018 N NE  . ARG D 1 267 ? 103.438 111.318 121.941 1.00 86.75  ? 213 ARG D NE  1 
ATOM   10019 C CZ  . ARG D 1 267 ? 102.983 110.382 121.119 1.00 85.62  ? 213 ARG D CZ  1 
ATOM   10020 N NH1 . ARG D 1 267 ? 102.930 110.577 119.812 1.00 84.73  ? 213 ARG D NH1 1 
ATOM   10021 N NH2 . ARG D 1 267 ? 102.569 109.223 121.623 1.00 80.91  ? 213 ARG D NH2 1 
ATOM   10022 N N   . LEU D 1 268 ? 109.074 112.979 121.271 1.00 64.35  ? 214 LEU D N   1 
ATOM   10023 C CA  . LEU D 1 268 ? 110.304 112.671 121.990 1.00 69.83  ? 214 LEU D CA  1 
ATOM   10024 C C   . LEU D 1 268 ? 110.051 112.767 123.487 1.00 73.71  ? 214 LEU D C   1 
ATOM   10025 O O   . LEU D 1 268 ? 109.642 113.823 123.982 1.00 75.07  ? 214 LEU D O   1 
ATOM   10026 C CB  . LEU D 1 268 ? 111.428 113.627 121.588 1.00 69.74  ? 214 LEU D CB  1 
ATOM   10027 C CG  . LEU D 1 268 ? 111.643 113.909 120.102 1.00 65.37  ? 214 LEU D CG  1 
ATOM   10028 C CD1 . LEU D 1 268 ? 112.770 114.910 119.915 1.00 66.07  ? 214 LEU D CD1 1 
ATOM   10029 C CD2 . LEU D 1 268 ? 111.940 112.628 119.352 1.00 66.16  ? 214 LEU D CD2 1 
ATOM   10030 N N   . LYS D 1 269 ? 110.308 111.677 124.203 1.00 71.79  ? 215 LYS D N   1 
ATOM   10031 C CA  . LYS D 1 269 ? 110.220 111.657 125.656 1.00 72.78  ? 215 LYS D CA  1 
ATOM   10032 C C   . LYS D 1 269 ? 111.621 111.761 126.241 1.00 76.47  ? 215 LYS D C   1 
ATOM   10033 O O   . LYS D 1 269 ? 112.501 110.964 125.902 1.00 78.34  ? 215 LYS D O   1 
ATOM   10034 C CB  . LYS D 1 269 ? 109.530 110.386 126.150 1.00 71.13  ? 215 LYS D CB  1 
ATOM   10035 C CG  . LYS D 1 269 ? 109.354 110.332 127.657 1.00 80.76  ? 215 LYS D CG  1 
ATOM   10036 C CD  . LYS D 1 269 ? 108.627 109.071 128.089 1.00 93.79  ? 215 LYS D CD  1 
ATOM   10037 C CE  . LYS D 1 269 ? 108.446 109.037 129.597 1.00 103.96 ? 215 LYS D CE  1 
ATOM   10038 N NZ  . LYS D 1 269 ? 107.769 107.792 130.051 1.00 107.65 ? 215 LYS D NZ  1 
ATOM   10039 N N   . ARG D 1 270 ? 111.823 112.741 127.117 1.00 76.05  ? 216 ARG D N   1 
ATOM   10040 C CA  . ARG D 1 270 ? 113.146 113.024 127.654 1.00 70.29  ? 216 ARG D CA  1 
ATOM   10041 C C   . ARG D 1 270 ? 113.565 111.955 128.655 1.00 73.35  ? 216 ARG D C   1 
ATOM   10042 O O   . ARG D 1 270 ? 112.743 111.436 129.414 1.00 73.63  ? 216 ARG D O   1 
ATOM   10043 C CB  . ARG D 1 270 ? 113.163 114.401 128.317 1.00 66.58  ? 216 ARG D CB  1 
ATOM   10044 C CG  . ARG D 1 270 ? 114.551 114.933 128.628 1.00 67.27  ? 216 ARG D CG  1 
ATOM   10045 C CD  . ARG D 1 270 ? 114.477 116.328 129.220 1.00 65.54  ? 216 ARG D CD  1 
ATOM   10046 N NE  . ARG D 1 270 ? 113.842 117.275 128.311 1.00 65.79  ? 216 ARG D NE  1 
ATOM   10047 C CZ  . ARG D 1 270 ? 114.501 118.061 127.471 1.00 69.60  ? 216 ARG D CZ  1 
ATOM   10048 N NH1 . ARG D 1 270 ? 115.822 118.042 127.400 1.00 69.97  ? 216 ARG D NH1 1 
ATOM   10049 N NH2 . ARG D 1 270 ? 113.818 118.888 126.685 1.00 69.14  ? 216 ARG D NH2 1 
ATOM   10050 N N   . ASN D 1 271 ? 114.855 111.627 128.648 1.00 73.48  ? 217 ASN D N   1 
ATOM   10051 C CA  . ASN D 1 271 ? 115.400 110.650 129.580 1.00 68.13  ? 217 ASN D CA  1 
ATOM   10052 C C   . ASN D 1 271 ? 115.700 111.318 130.916 1.00 68.33  ? 217 ASN D C   1 
ATOM   10053 O O   . ASN D 1 271 ? 116.408 112.328 130.973 1.00 75.18  ? 217 ASN D O   1 
ATOM   10054 C CB  . ASN D 1 271 ? 116.662 110.010 129.005 1.00 68.87  ? 217 ASN D CB  1 
ATOM   10055 C CG  . ASN D 1 271 ? 116.373 109.136 127.799 1.00 75.54  ? 217 ASN D CG  1 
ATOM   10056 O OD1 . ASN D 1 271 ? 115.337 108.476 127.730 1.00 76.04  ? 217 ASN D OD1 1 
ATOM   10057 N ND2 . ASN D 1 271 ? 117.292 109.129 126.839 1.00 76.11  ? 217 ASN D ND2 1 
ATOM   10058 N N   . ILE D 1 272 ? 115.157 110.744 131.993 1.00 66.07  ? 218 ILE D N   1 
ATOM   10059 C CA  . ILE D 1 272 ? 115.218 111.364 133.315 1.00 65.17  ? 218 ILE D CA  1 
ATOM   10060 C C   . ILE D 1 272 ? 116.488 111.019 134.082 1.00 63.70  ? 218 ILE D C   1 
ATOM   10061 O O   . ILE D 1 272 ? 116.800 111.691 135.077 1.00 65.03  ? 218 ILE D O   1 
ATOM   10062 C CB  . ILE D 1 272 ? 113.970 110.954 134.124 1.00 62.75  ? 218 ILE D CB  1 
ATOM   10063 C CG1 . ILE D 1 272 ? 113.765 111.872 135.330 1.00 58.05  ? 218 ILE D CG1 1 
ATOM   10064 C CG2 . ILE D 1 272 ? 114.067 109.497 134.553 1.00 64.32  ? 218 ILE D CG2 1 
ATOM   10065 C CD1 . ILE D 1 272 ? 113.585 113.324 134.963 1.00 56.82  ? 218 ILE D CD1 1 
ATOM   10066 N N   . GLY D 1 273 ? 117.242 110.015 133.644 1.00 61.73  ? 219 GLY D N   1 
ATOM   10067 C CA  . GLY D 1 273 ? 118.371 109.518 134.407 1.00 68.04  ? 219 GLY D CA  1 
ATOM   10068 C C   . GLY D 1 273 ? 119.477 110.516 134.687 1.00 68.41  ? 219 GLY D C   1 
ATOM   10069 O O   . GLY D 1 273 ? 120.017 110.550 135.798 1.00 74.53  ? 219 GLY D O   1 
ATOM   10070 N N   . TYR D 1 274 ? 119.832 111.329 133.691 1.00 60.91  ? 220 TYR D N   1 
ATOM   10071 C CA  . TYR D 1 274 ? 120.931 112.275 133.861 1.00 64.28  ? 220 TYR D CA  1 
ATOM   10072 C C   . TYR D 1 274 ? 120.623 113.296 134.949 1.00 68.47  ? 220 TYR D C   1 
ATOM   10073 O O   . TYR D 1 274 ? 121.474 113.604 135.790 1.00 71.98  ? 220 TYR D O   1 
ATOM   10074 C CB  . TYR D 1 274 ? 121.226 112.976 132.536 1.00 70.86  ? 220 TYR D CB  1 
ATOM   10075 C CG  . TYR D 1 274 ? 122.210 114.118 132.653 1.00 77.92  ? 220 TYR D CG  1 
ATOM   10076 C CD1 . TYR D 1 274 ? 123.576 113.880 132.722 1.00 79.31  ? 220 TYR D CD1 1 
ATOM   10077 C CD2 . TYR D 1 274 ? 121.772 115.435 132.686 1.00 75.84  ? 220 TYR D CD2 1 
ATOM   10078 C CE1 . TYR D 1 274 ? 124.477 114.922 132.826 1.00 80.89  ? 220 TYR D CE1 1 
ATOM   10079 C CE2 . TYR D 1 274 ? 122.666 116.481 132.790 1.00 81.97  ? 220 TYR D CE2 1 
ATOM   10080 C CZ  . TYR D 1 274 ? 124.016 116.220 132.859 1.00 85.87  ? 220 TYR D CZ  1 
ATOM   10081 O OH  . TYR D 1 274 ? 124.908 117.262 132.962 1.00 84.47  ? 220 TYR D OH  1 
ATOM   10082 N N   . PHE D 1 275 ? 119.405 113.838 134.943 1.00 65.18  ? 221 PHE D N   1 
ATOM   10083 C CA  . PHE D 1 275 ? 119.036 114.815 135.959 1.00 62.08  ? 221 PHE D CA  1 
ATOM   10084 C C   . PHE D 1 275 ? 118.932 114.174 137.333 1.00 61.01  ? 221 PHE D C   1 
ATOM   10085 O O   . PHE D 1 275 ? 119.143 114.846 138.348 1.00 62.32  ? 221 PHE D O   1 
ATOM   10086 C CB  . PHE D 1 275 ? 117.727 115.494 135.571 1.00 60.33  ? 221 PHE D CB  1 
ATOM   10087 C CG  . PHE D 1 275 ? 117.747 116.077 134.193 1.00 62.34  ? 221 PHE D CG  1 
ATOM   10088 C CD1 . PHE D 1 275 ? 118.291 117.329 133.965 1.00 65.65  ? 221 PHE D CD1 1 
ATOM   10089 C CD2 . PHE D 1 275 ? 117.240 115.365 133.120 1.00 63.88  ? 221 PHE D CD2 1 
ATOM   10090 C CE1 . PHE D 1 275 ? 118.319 117.863 132.696 1.00 68.78  ? 221 PHE D CE1 1 
ATOM   10091 C CE2 . PHE D 1 275 ? 117.266 115.895 131.849 1.00 66.81  ? 221 PHE D CE2 1 
ATOM   10092 C CZ  . PHE D 1 275 ? 117.805 117.145 131.636 1.00 70.34  ? 221 PHE D CZ  1 
ATOM   10093 N N   . ILE D 1 276 ? 118.605 112.883 137.385 1.00 61.64  ? 222 ILE D N   1 
ATOM   10094 C CA  . ILE D 1 276 ? 118.675 112.152 138.645 1.00 59.20  ? 222 ILE D CA  1 
ATOM   10095 C C   . ILE D 1 276 ? 120.114 112.104 139.141 1.00 58.37  ? 222 ILE D C   1 
ATOM   10096 O O   . ILE D 1 276 ? 120.401 112.400 140.305 1.00 63.29  ? 222 ILE D O   1 
ATOM   10097 C CB  . ILE D 1 276 ? 118.087 110.740 138.478 1.00 58.45  ? 222 ILE D CB  1 
ATOM   10098 C CG1 . ILE D 1 276 ? 116.573 110.811 138.288 1.00 59.69  ? 222 ILE D CG1 1 
ATOM   10099 C CG2 . ILE D 1 276 ? 118.433 109.872 139.672 1.00 57.97  ? 222 ILE D CG2 1 
ATOM   10100 C CD1 . ILE D 1 276 ? 115.839 111.333 139.496 1.00 58.59  ? 222 ILE D CD1 1 
ATOM   10101 N N   . LEU D 1 277 ? 121.044 111.757 138.252 1.00 60.90  ? 223 LEU D N   1 
ATOM   10102 C CA  . LEU D 1 277 ? 122.440 111.608 138.645 1.00 62.95  ? 223 LEU D CA  1 
ATOM   10103 C C   . LEU D 1 277 ? 123.150 112.936 138.867 1.00 65.45  ? 223 LEU D C   1 
ATOM   10104 O O   . LEU D 1 277 ? 124.249 112.937 139.430 1.00 71.16  ? 223 LEU D O   1 
ATOM   10105 C CB  . LEU D 1 277 ? 123.203 110.814 137.586 1.00 70.47  ? 223 LEU D CB  1 
ATOM   10106 C CG  . LEU D 1 277 ? 122.681 109.419 137.256 1.00 73.95  ? 223 LEU D CG  1 
ATOM   10107 C CD1 . LEU D 1 277 ? 123.516 108.805 136.149 1.00 77.45  ? 223 LEU D CD1 1 
ATOM   10108 C CD2 . LEU D 1 277 ? 122.691 108.542 138.494 1.00 71.22  ? 223 LEU D CD2 1 
ATOM   10109 N N   . GLN D 1 278 ? 122.568 114.054 138.442 1.00 62.01  ? 224 GLN D N   1 
ATOM   10110 C CA  . GLN D 1 278 ? 123.279 115.324 138.476 1.00 66.37  ? 224 GLN D CA  1 
ATOM   10111 C C   . GLN D 1 278 ? 122.581 116.419 139.266 1.00 69.71  ? 224 GLN D C   1 
ATOM   10112 O O   . GLN D 1 278 ? 123.261 117.310 139.777 1.00 74.58  ? 224 GLN D O   1 
ATOM   10113 C CB  . GLN D 1 278 ? 123.525 115.831 137.048 1.00 68.17  ? 224 GLN D CB  1 
ATOM   10114 C CG  . GLN D 1 278 ? 124.852 116.542 136.874 1.00 73.74  ? 224 GLN D CG  1 
ATOM   10115 C CD  . GLN D 1 278 ? 126.031 115.643 137.189 1.00 74.65  ? 224 GLN D CD  1 
ATOM   10116 O OE1 . GLN D 1 278 ? 126.446 114.831 136.363 1.00 79.92  ? 224 GLN D OE1 1 
ATOM   10117 N NE2 . GLN D 1 278 ? 126.576 115.781 138.392 1.00 69.99  ? 224 GLN D NE2 1 
ATOM   10118 N N   . THR D 1 279 ? 121.255 116.387 139.382 1.00 68.23  ? 225 THR D N   1 
ATOM   10119 C CA  . THR D 1 279 ? 120.529 117.455 140.058 1.00 64.05  ? 225 THR D CA  1 
ATOM   10120 C C   . THR D 1 279 ? 119.790 116.984 141.300 1.00 63.58  ? 225 THR D C   1 
ATOM   10121 O O   . THR D 1 279 ? 119.974 117.559 142.378 1.00 68.30  ? 225 THR D O   1 
ATOM   10122 C CB  . THR D 1 279 ? 119.541 118.117 139.086 1.00 63.74  ? 225 THR D CB  1 
ATOM   10123 O OG1 . THR D 1 279 ? 118.657 117.125 138.551 1.00 65.75  ? 225 THR D OG1 1 
ATOM   10124 C CG2 . THR D 1 279 ? 120.286 118.789 137.947 1.00 70.65  ? 225 THR D CG2 1 
ATOM   10125 N N   . TYR D 1 280 ? 118.954 115.951 141.184 1.00 62.63  ? 226 TYR D N   1 
ATOM   10126 C CA  . TYR D 1 280 ? 118.100 115.564 142.304 1.00 60.18  ? 226 TYR D CA  1 
ATOM   10127 C C   . TYR D 1 280 ? 118.906 114.932 143.434 1.00 63.93  ? 226 TYR D C   1 
ATOM   10128 O O   . TYR D 1 280 ? 118.698 115.251 144.612 1.00 67.94  ? 226 TYR D O   1 
ATOM   10129 C CB  . TYR D 1 280 ? 117.002 114.618 141.817 1.00 53.07  ? 226 TYR D CB  1 
ATOM   10130 C CG  . TYR D 1 280 ? 115.995 115.286 140.909 1.00 57.27  ? 226 TYR D CG  1 
ATOM   10131 C CD1 . TYR D 1 280 ? 114.874 115.912 141.429 1.00 59.34  ? 226 TYR D CD1 1 
ATOM   10132 C CD2 . TYR D 1 280 ? 116.170 115.298 139.533 1.00 62.63  ? 226 TYR D CD2 1 
ATOM   10133 C CE1 . TYR D 1 280 ? 113.954 116.528 140.607 1.00 60.55  ? 226 TYR D CE1 1 
ATOM   10134 C CE2 . TYR D 1 280 ? 115.253 115.912 138.702 1.00 60.26  ? 226 TYR D CE2 1 
ATOM   10135 C CZ  . TYR D 1 280 ? 114.147 116.525 139.245 1.00 58.19  ? 226 TYR D CZ  1 
ATOM   10136 O OH  . TYR D 1 280 ? 113.230 117.137 138.425 1.00 64.06  ? 226 TYR D OH  1 
ATOM   10137 N N   . MET D 1 281 ? 119.826 114.026 143.098 1.00 61.01  ? 227 MET D N   1 
ATOM   10138 C CA  . MET D 1 281 ? 120.613 113.359 144.134 1.00 60.81  ? 227 MET D CA  1 
ATOM   10139 C C   . MET D 1 281 ? 121.475 114.320 144.943 1.00 66.22  ? 227 MET D C   1 
ATOM   10140 O O   . MET D 1 281 ? 121.512 114.181 146.178 1.00 72.14  ? 227 MET D O   1 
ATOM   10141 C CB  . MET D 1 281 ? 121.458 112.240 143.516 1.00 57.94  ? 227 MET D CB  1 
ATOM   10142 C CG  . MET D 1 281 ? 120.657 111.026 143.074 1.00 64.94  ? 227 MET D CG  1 
ATOM   10143 S SD  . MET D 1 281 ? 119.555 110.390 144.349 1.00 79.42  ? 227 MET D SD  1 
ATOM   10144 C CE  . MET D 1 281 ? 120.727 109.928 145.621 1.00 76.28  ? 227 MET D CE  1 
ATOM   10145 N N   . PRO D 1 282 ? 122.211 115.270 144.348 1.00 64.94  ? 228 PRO D N   1 
ATOM   10146 C CA  . PRO D 1 282 ? 122.958 116.220 145.192 1.00 72.17  ? 228 PRO D CA  1 
ATOM   10147 C C   . PRO D 1 282 ? 122.072 117.016 146.136 1.00 67.98  ? 228 PRO D C   1 
ATOM   10148 O O   . PRO D 1 282 ? 122.448 117.238 147.293 1.00 66.02  ? 228 PRO D O   1 
ATOM   10149 C CB  . PRO D 1 282 ? 123.655 117.123 144.166 1.00 69.58  ? 228 PRO D CB  1 
ATOM   10150 C CG  . PRO D 1 282 ? 123.773 116.287 142.953 1.00 61.15  ? 228 PRO D CG  1 
ATOM   10151 C CD  . PRO D 1 282 ? 122.528 115.457 142.920 1.00 59.11  ? 228 PRO D CD  1 
ATOM   10152 N N   . SER D 1 283 ? 120.895 117.443 145.676 1.00 63.37  ? 229 SER D N   1 
ATOM   10153 C CA  . SER D 1 283 ? 119.989 118.189 146.543 1.00 62.67  ? 229 SER D CA  1 
ATOM   10154 C C   . SER D 1 283 ? 119.485 117.322 147.689 1.00 69.37  ? 229 SER D C   1 
ATOM   10155 O O   . SER D 1 283 ? 119.410 117.779 148.839 1.00 74.95  ? 229 SER D O   1 
ATOM   10156 C CB  . SER D 1 283 ? 118.820 118.735 145.727 1.00 61.56  ? 229 SER D CB  1 
ATOM   10157 O OG  . SER D 1 283 ? 119.285 119.475 144.613 1.00 69.66  ? 229 SER D OG  1 
ATOM   10158 N N   . ILE D 1 284 ? 119.138 116.067 147.394 1.00 66.56  ? 230 ILE D N   1 
ATOM   10159 C CA  . ILE D 1 284 ? 118.703 115.152 148.445 1.00 65.33  ? 230 ILE D CA  1 
ATOM   10160 C C   . ILE D 1 284 ? 119.819 114.942 149.459 1.00 68.46  ? 230 ILE D C   1 
ATOM   10161 O O   . ILE D 1 284 ? 119.581 114.922 150.673 1.00 72.88  ? 230 ILE D O   1 
ATOM   10162 C CB  . ILE D 1 284 ? 118.232 113.821 147.832 1.00 62.07  ? 230 ILE D CB  1 
ATOM   10163 C CG1 . ILE D 1 284 ? 116.944 114.029 147.036 1.00 63.25  ? 230 ILE D CG1 1 
ATOM   10164 C CG2 . ILE D 1 284 ? 118.030 112.774 148.913 1.00 66.16  ? 230 ILE D CG2 1 
ATOM   10165 C CD1 . ILE D 1 284 ? 116.404 112.765 146.412 1.00 67.52  ? 230 ILE D CD1 1 
ATOM   10166 N N   . LEU D 1 285 ? 121.054 114.789 148.980 1.00 64.10  ? 231 LEU D N   1 
ATOM   10167 C CA  . LEU D 1 285 ? 122.181 114.588 149.884 1.00 64.85  ? 231 LEU D CA  1 
ATOM   10168 C C   . LEU D 1 285 ? 122.436 115.812 150.752 1.00 70.25  ? 231 LEU D C   1 
ATOM   10169 O O   . LEU D 1 285 ? 122.762 115.671 151.933 1.00 75.82  ? 231 LEU D O   1 
ATOM   10170 C CB  . LEU D 1 285 ? 123.430 114.224 149.086 1.00 64.01  ? 231 LEU D CB  1 
ATOM   10171 C CG  . LEU D 1 285 ? 123.352 112.863 148.394 1.00 71.64  ? 231 LEU D CG  1 
ATOM   10172 C CD1 . LEU D 1 285 ? 124.392 112.753 147.294 1.00 74.32  ? 231 LEU D CD1 1 
ATOM   10173 C CD2 . LEU D 1 285 ? 123.514 111.742 149.407 1.00 69.18  ? 231 LEU D CD2 1 
ATOM   10174 N N   . ILE D 1 286 ? 122.293 117.016 150.197 1.00 67.51  ? 232 ILE D N   1 
ATOM   10175 C CA  . ILE D 1 286 ? 122.462 118.216 151.015 1.00 65.45  ? 232 ILE D CA  1 
ATOM   10176 C C   . ILE D 1 286 ? 121.352 118.323 152.059 1.00 64.08  ? 232 ILE D C   1 
ATOM   10177 O O   . ILE D 1 286 ? 121.597 118.733 153.204 1.00 68.24  ? 232 ILE D O   1 
ATOM   10178 C CB  . ILE D 1 286 ? 122.528 119.469 150.123 1.00 64.14  ? 232 ILE D CB  1 
ATOM   10179 C CG1 . ILE D 1 286 ? 123.717 119.376 149.167 1.00 70.08  ? 232 ILE D CG1 1 
ATOM   10180 C CG2 . ILE D 1 286 ? 122.648 120.722 150.966 1.00 61.38  ? 232 ILE D CG2 1 
ATOM   10181 C CD1 . ILE D 1 286 ? 125.040 119.156 149.861 1.00 65.75  ? 232 ILE D CD1 1 
ATOM   10182 N N   . THR D 1 287 ? 120.120 117.957 151.696 1.00 60.64  ? 233 THR D N   1 
ATOM   10183 C CA  . THR D 1 287 ? 119.044 117.955 152.683 1.00 67.41  ? 233 THR D CA  1 
ATOM   10184 C C   . THR D 1 287 ? 119.320 116.948 153.797 1.00 72.85  ? 233 THR D C   1 
ATOM   10185 O O   . THR D 1 287 ? 119.088 117.233 154.981 1.00 76.28  ? 233 THR D O   1 
ATOM   10186 C CB  . THR D 1 287 ? 117.710 117.658 152.002 1.00 66.85  ? 233 THR D CB  1 
ATOM   10187 O OG1 . THR D 1 287 ? 117.528 118.558 150.903 1.00 60.10  ? 233 THR D OG1 1 
ATOM   10188 C CG2 . THR D 1 287 ? 116.563 117.834 152.982 1.00 75.03  ? 233 THR D CG2 1 
ATOM   10189 N N   . ILE D 1 288 ? 119.827 115.769 153.440 1.00 67.36  ? 234 ILE D N   1 
ATOM   10190 C CA  . ILE D 1 288 ? 120.198 114.788 154.455 1.00 68.26  ? 234 ILE D CA  1 
ATOM   10191 C C   . ILE D 1 288 ? 121.358 115.307 155.298 1.00 75.11  ? 234 ILE D C   1 
ATOM   10192 O O   . ILE D 1 288 ? 121.465 114.997 156.487 1.00 79.58  ? 234 ILE D O   1 
ATOM   10193 C CB  . ILE D 1 288 ? 120.521 113.433 153.802 1.00 71.20  ? 234 ILE D CB  1 
ATOM   10194 C CG1 . ILE D 1 288 ? 119.309 112.921 153.026 1.00 74.68  ? 234 ILE D CG1 1 
ATOM   10195 C CG2 . ILE D 1 288 ? 120.912 112.411 154.852 1.00 75.72  ? 234 ILE D CG2 1 
ATOM   10196 C CD1 . ILE D 1 288 ? 119.562 111.633 152.278 1.00 78.01  ? 234 ILE D CD1 1 
ATOM   10197 N N   . LEU D 1 289 ? 122.243 116.105 154.700 1.00 71.06  ? 235 LEU D N   1 
ATOM   10198 C CA  . LEU D 1 289 ? 123.318 116.729 155.466 1.00 67.24  ? 235 LEU D CA  1 
ATOM   10199 C C   . LEU D 1 289 ? 122.763 117.696 156.505 1.00 71.66  ? 235 LEU D C   1 
ATOM   10200 O O   . LEU D 1 289 ? 123.265 117.769 157.633 1.00 75.06  ? 235 LEU D O   1 
ATOM   10201 C CB  . LEU D 1 289 ? 124.280 117.445 154.520 1.00 63.90  ? 235 LEU D CB  1 
ATOM   10202 C CG  . LEU D 1 289 ? 125.709 117.626 155.024 1.00 62.85  ? 235 LEU D CG  1 
ATOM   10203 C CD1 . LEU D 1 289 ? 126.294 116.277 155.386 1.00 68.65  ? 235 LEU D CD1 1 
ATOM   10204 C CD2 . LEU D 1 289 ? 126.564 118.317 153.976 1.00 58.48  ? 235 LEU D CD2 1 
ATOM   10205 N N   . SER D 1 290 ? 121.734 118.459 156.139 1.00 68.77  ? 236 SER D N   1 
ATOM   10206 C CA  . SER D 1 290 ? 121.063 119.306 157.124 1.00 68.54  ? 236 SER D CA  1 
ATOM   10207 C C   . SER D 1 290 ? 120.434 118.458 158.227 1.00 76.76  ? 236 SER D C   1 
ATOM   10208 O O   . SER D 1 290 ? 120.495 118.801 159.417 1.00 82.05  ? 236 SER D O   1 
ATOM   10209 C CB  . SER D 1 290 ? 120.009 120.178 156.441 1.00 65.39  ? 236 SER D CB  1 
ATOM   10210 O OG  . SER D 1 290 ? 118.878 119.413 156.067 1.00 66.64  ? 236 SER D OG  1 
ATOM   10211 N N   . TRP D 1 291 ? 119.822 117.337 157.847 1.00 75.78  ? 237 TRP D N   1 
ATOM   10212 C CA  . TRP D 1 291 ? 119.289 116.422 158.853 1.00 78.42  ? 237 TRP D CA  1 
ATOM   10213 C C   . TRP D 1 291 ? 120.388 115.886 159.765 1.00 79.37  ? 237 TRP D C   1 
ATOM   10214 O O   . TRP D 1 291 ? 120.139 115.605 160.942 1.00 78.60  ? 237 TRP D O   1 
ATOM   10215 C CB  . TRP D 1 291 ? 118.551 115.271 158.174 1.00 82.15  ? 237 TRP D CB  1 
ATOM   10216 C CG  . TRP D 1 291 ? 117.393 115.720 157.354 1.00 79.49  ? 237 TRP D CG  1 
ATOM   10217 C CD1 . TRP D 1 291 ? 116.797 116.946 157.379 1.00 71.90  ? 237 TRP D CD1 1 
ATOM   10218 C CD2 . TRP D 1 291 ? 116.690 114.952 156.374 1.00 78.62  ? 237 TRP D CD2 1 
ATOM   10219 N NE1 . TRP D 1 291 ? 115.762 116.987 156.478 1.00 73.37  ? 237 TRP D NE1 1 
ATOM   10220 C CE2 . TRP D 1 291 ? 115.676 115.774 155.849 1.00 75.96  ? 237 TRP D CE2 1 
ATOM   10221 C CE3 . TRP D 1 291 ? 116.817 113.646 155.892 1.00 76.35  ? 237 TRP D CE3 1 
ATOM   10222 C CZ2 . TRP D 1 291 ? 114.799 115.335 154.867 1.00 78.19  ? 237 TRP D CZ2 1 
ATOM   10223 C CZ3 . TRP D 1 291 ? 115.943 113.212 154.918 1.00 75.35  ? 237 TRP D CZ3 1 
ATOM   10224 C CH2 . TRP D 1 291 ? 114.947 114.054 154.415 1.00 78.76  ? 237 TRP D CH2 1 
ATOM   10225 N N   . VAL D 1 292 ? 121.595 115.708 159.233 1.00 78.63  ? 238 VAL D N   1 
ATOM   10226 C CA  . VAL D 1 292 ? 122.762 115.308 160.012 1.00 75.55  ? 238 VAL D CA  1 
ATOM   10227 C C   . VAL D 1 292 ? 123.091 116.414 161.003 1.00 74.22  ? 238 VAL D C   1 
ATOM   10228 O O   . VAL D 1 292 ? 123.382 116.151 162.175 1.00 75.11  ? 238 VAL D O   1 
ATOM   10229 C CB  . VAL D 1 292 ? 123.966 115.003 159.102 1.00 76.37  ? 238 VAL D CB  1 
ATOM   10230 C CG1 . VAL D 1 292 ? 125.239 114.880 159.919 1.00 73.50  ? 238 VAL D CG1 1 
ATOM   10231 C CG2 . VAL D 1 292 ? 123.721 113.731 158.309 1.00 82.19  ? 238 VAL D CG2 1 
ATOM   10232 N N   . SER D 1 293 ? 123.054 117.658 160.527 1.00 76.93  ? 239 SER D N   1 
ATOM   10233 C CA  . SER D 1 293 ? 123.255 118.831 161.374 1.00 83.68  ? 239 SER D CA  1 
ATOM   10234 C C   . SER D 1 293 ? 122.292 118.812 162.551 1.00 82.03  ? 239 SER D C   1 
ATOM   10235 O O   . SER D 1 293 ? 122.635 119.242 163.657 1.00 82.54  ? 239 SER D O   1 
ATOM   10236 C CB  . SER D 1 293 ? 123.069 120.119 160.569 1.00 82.85  ? 239 SER D CB  1 
ATOM   10237 O OG  . SER D 1 293 ? 122.695 121.196 161.409 1.00 78.37  ? 239 SER D OG  1 
ATOM   10238 N N   . PHE D 1 294 ? 121.081 118.319 162.307 1.00 79.87  ? 240 PHE D N   1 
ATOM   10239 C CA  . PHE D 1 294 ? 120.068 118.228 163.355 1.00 81.04  ? 240 PHE D CA  1 
ATOM   10240 C C   . PHE D 1 294 ? 120.516 117.378 164.540 1.00 83.03  ? 240 PHE D C   1 
ATOM   10241 O O   . PHE D 1 294 ? 120.282 117.748 165.696 1.00 82.32  ? 240 PHE D O   1 
ATOM   10242 C CB  . PHE D 1 294 ? 118.770 117.650 162.796 1.00 79.43  ? 240 PHE D CB  1 
ATOM   10243 C CG  . PHE D 1 294 ? 117.861 118.671 162.200 1.00 80.15  ? 240 PHE D CG  1 
ATOM   10244 C CD1 . PHE D 1 294 ? 117.847 119.965 162.682 1.00 77.41  ? 240 PHE D CD1 1 
ATOM   10245 C CD2 . PHE D 1 294 ? 117.018 118.337 161.157 1.00 82.90  ? 240 PHE D CD2 1 
ATOM   10246 C CE1 . PHE D 1 294 ? 117.010 120.907 162.136 1.00 81.39  ? 240 PHE D CE1 1 
ATOM   10247 C CE2 . PHE D 1 294 ? 116.181 119.276 160.607 1.00 82.64  ? 240 PHE D CE2 1 
ATOM   10248 C CZ  . PHE D 1 294 ? 116.173 120.562 161.099 1.00 84.22  ? 240 PHE D CZ  1 
ATOM   10249 N N   . TRP D 1 295 ? 121.152 116.239 164.268 1.00 83.99  ? 241 TRP D N   1 
ATOM   10250 C CA  . TRP D 1 295 ? 121.440 115.250 165.302 1.00 82.69  ? 241 TRP D CA  1 
ATOM   10251 C C   . TRP D 1 295 ? 122.586 115.659 166.223 1.00 81.61  ? 241 TRP D C   1 
ATOM   10252 O O   . TRP D 1 295 ? 122.696 115.144 167.340 1.00 77.07  ? 241 TRP D O   1 
ATOM   10253 C CB  . TRP D 1 295 ? 121.750 113.896 164.661 1.00 81.76  ? 241 TRP D CB  1 
ATOM   10254 C CG  . TRP D 1 295 ? 120.681 112.873 164.886 1.00 83.37  ? 241 TRP D CG  1 
ATOM   10255 C CD1 . TRP D 1 295 ? 120.621 111.963 165.899 1.00 83.02  ? 241 TRP D CD1 1 
ATOM   10256 C CD2 . TRP D 1 295 ? 119.515 112.659 164.083 1.00 83.99  ? 241 TRP D CD2 1 
ATOM   10257 N NE1 . TRP D 1 295 ? 119.491 111.193 165.777 1.00 80.85  ? 241 TRP D NE1 1 
ATOM   10258 C CE2 . TRP D 1 295 ? 118.794 111.600 164.670 1.00 83.33  ? 241 TRP D CE2 1 
ATOM   10259 C CE3 . TRP D 1 295 ? 119.010 113.257 162.926 1.00 81.33  ? 241 TRP D CE3 1 
ATOM   10260 C CZ2 . TRP D 1 295 ? 117.597 111.128 164.139 1.00 85.99  ? 241 TRP D CZ2 1 
ATOM   10261 C CZ3 . TRP D 1 295 ? 117.822 112.788 162.401 1.00 81.51  ? 241 TRP D CZ3 1 
ATOM   10262 C CH2 . TRP D 1 295 ? 117.129 111.733 163.007 1.00 87.09  ? 241 TRP D CH2 1 
ATOM   10263 N N   . ILE D 1 296 ? 123.448 116.570 165.765 1.00 83.94  ? 242 ILE D N   1 
ATOM   10264 C CA  . ILE D 1 296 ? 124.581 116.995 166.579 1.00 80.29  ? 242 ILE D CA  1 
ATOM   10265 C C   . ILE D 1 296 ? 124.079 117.680 167.843 1.00 84.71  ? 242 ILE D C   1 
ATOM   10266 O O   . ILE D 1 296 ? 123.077 118.407 167.824 1.00 88.94  ? 242 ILE D O   1 
ATOM   10267 C CB  . ILE D 1 296 ? 125.506 117.917 165.766 1.00 79.06  ? 242 ILE D CB  1 
ATOM   10268 C CG1 . ILE D 1 296 ? 126.057 117.173 164.551 1.00 79.26  ? 242 ILE D CG1 1 
ATOM   10269 C CG2 . ILE D 1 296 ? 126.654 118.427 166.622 1.00 83.27  ? 242 ILE D CG2 1 
ATOM   10270 C CD1 . ILE D 1 296 ? 126.925 115.992 164.909 1.00 82.78  ? 242 ILE D CD1 1 
ATOM   10271 N N   . ASN D 1 297 ? 124.766 117.428 168.957 1.00 85.00  ? 243 ASN D N   1 
ATOM   10272 C CA  . ASN D 1 297 ? 124.378 118.013 170.234 1.00 92.40  ? 243 ASN D CA  1 
ATOM   10273 C C   . ASN D 1 297 ? 124.349 119.533 170.128 1.00 97.68  ? 243 ASN D C   1 
ATOM   10274 O O   . ASN D 1 297 ? 125.277 120.149 169.598 1.00 99.13  ? 243 ASN D O   1 
ATOM   10275 C CB  . ASN D 1 297 ? 125.347 117.571 171.328 1.00 96.21  ? 243 ASN D CB  1 
ATOM   10276 C CG  . ASN D 1 297 ? 124.800 117.804 172.719 1.00 104.52 ? 243 ASN D CG  1 
ATOM   10277 O OD1 . ASN D 1 297 ? 123.589 117.916 172.910 1.00 111.20 ? 243 ASN D OD1 1 
ATOM   10278 N ND2 . ASN D 1 297 ? 125.690 117.876 173.701 1.00 106.75 ? 243 ASN D ND2 1 
ATOM   10279 N N   . TYR D 1 298 ? 123.273 120.136 170.642 1.00 101.70 ? 244 TYR D N   1 
ATOM   10280 C CA  . TYR D 1 298 ? 123.006 121.547 170.393 1.00 103.72 ? 244 TYR D CA  1 
ATOM   10281 C C   . TYR D 1 298 ? 123.995 122.485 171.073 1.00 104.12 ? 244 TYR D C   1 
ATOM   10282 O O   . TYR D 1 298 ? 124.026 123.670 170.726 1.00 101.85 ? 244 TYR D O   1 
ATOM   10283 C CB  . TYR D 1 298 ? 121.579 121.898 170.825 1.00 102.40 ? 244 TYR D CB  1 
ATOM   10284 C CG  . TYR D 1 298 ? 121.239 121.533 172.253 1.00 105.71 ? 244 TYR D CG  1 
ATOM   10285 C CD1 . TYR D 1 298 ? 121.502 122.410 173.296 1.00 111.35 ? 244 TYR D CD1 1 
ATOM   10286 C CD2 . TYR D 1 298 ? 120.640 120.318 172.554 1.00 103.88 ? 244 TYR D CD2 1 
ATOM   10287 C CE1 . TYR D 1 298 ? 121.188 122.083 174.601 1.00 115.86 ? 244 TYR D CE1 1 
ATOM   10288 C CE2 . TYR D 1 298 ? 120.322 119.982 173.856 1.00 110.43 ? 244 TYR D CE2 1 
ATOM   10289 C CZ  . TYR D 1 298 ? 120.598 120.868 174.875 1.00 119.13 ? 244 TYR D CZ  1 
ATOM   10290 O OH  . TYR D 1 298 ? 120.283 120.539 176.172 1.00 125.01 ? 244 TYR D OH  1 
ATOM   10291 N N   . ASP D 1 299 ? 124.802 122.000 172.016 1.00 102.58 ? 245 ASP D N   1 
ATOM   10292 C CA  . ASP D 1 299 ? 125.792 122.865 172.645 1.00 102.22 ? 245 ASP D CA  1 
ATOM   10293 C C   . ASP D 1 299 ? 127.031 123.069 171.782 1.00 102.63 ? 245 ASP D C   1 
ATOM   10294 O O   . ASP D 1 299 ? 127.879 123.897 172.133 1.00 99.94  ? 245 ASP D O   1 
ATOM   10295 C CB  . ASP D 1 299 ? 126.197 122.305 174.010 1.00 105.48 ? 245 ASP D CB  1 
ATOM   10296 C CG  . ASP D 1 299 ? 126.888 120.963 173.909 1.00 111.48 ? 245 ASP D CG  1 
ATOM   10297 O OD1 . ASP D 1 299 ? 126.632 120.233 172.929 1.00 111.11 ? 245 ASP D OD1 1 
ATOM   10298 O OD2 . ASP D 1 299 ? 127.686 120.637 174.813 1.00 115.10 ? 245 ASP D OD2 1 
ATOM   10299 N N   . ALA D 1 300 ? 127.156 122.343 170.672 1.00 101.51 ? 246 ALA D N   1 
ATOM   10300 C CA  . ALA D 1 300 ? 128.263 122.522 169.734 1.00 95.16  ? 246 ALA D CA  1 
ATOM   10301 C C   . ALA D 1 300 ? 127.832 123.556 168.703 1.00 92.65  ? 246 ALA D C   1 
ATOM   10302 O O   . ALA D 1 300 ? 127.291 123.228 167.647 1.00 91.53  ? 246 ALA D O   1 
ATOM   10303 C CB  . ALA D 1 300 ? 128.644 121.199 169.085 1.00 90.28  ? 246 ALA D CB  1 
ATOM   10304 N N   . SER D 1 301 ? 128.073 124.829 169.022 1.00 93.83  ? 247 SER D N   1 
ATOM   10305 C CA  . SER D 1 301 ? 127.564 125.915 168.191 1.00 92.84  ? 247 SER D CA  1 
ATOM   10306 C C   . SER D 1 301 ? 128.257 125.961 166.834 1.00 89.91  ? 247 SER D C   1 
ATOM   10307 O O   . SER D 1 301 ? 127.596 126.030 165.789 1.00 89.20  ? 247 SER D O   1 
ATOM   10308 C CB  . SER D 1 301 ? 127.728 127.246 168.923 1.00 92.82  ? 247 SER D CB  1 
ATOM   10309 O OG  . SER D 1 301 ? 129.079 127.458 169.293 1.00 96.06  ? 247 SER D OG  1 
ATOM   10310 N N   . ALA D 1 302 ? 129.592 125.921 166.831 1.00 87.48  ? 248 ALA D N   1 
ATOM   10311 C CA  . ALA D 1 302 ? 130.341 126.122 165.595 1.00 84.02  ? 248 ALA D CA  1 
ATOM   10312 C C   . ALA D 1 302 ? 130.035 125.036 164.575 1.00 81.80  ? 248 ALA D C   1 
ATOM   10313 O O   . ALA D 1 302 ? 129.866 125.322 163.383 1.00 83.56  ? 248 ALA D O   1 
ATOM   10314 C CB  . ALA D 1 302 ? 131.839 126.167 165.893 1.00 80.51  ? 248 ALA D CB  1 
ATOM   10315 N N   . ALA D 1 303 ? 129.954 123.784 165.027 1.00 80.96  ? 249 ALA D N   1 
ATOM   10316 C CA  . ALA D 1 303 ? 129.717 122.670 164.115 1.00 82.77  ? 249 ALA D CA  1 
ATOM   10317 C C   . ALA D 1 303 ? 128.390 122.826 163.385 1.00 80.53  ? 249 ALA D C   1 
ATOM   10318 O O   . ALA D 1 303 ? 128.332 122.759 162.149 1.00 79.95  ? 249 ALA D O   1 
ATOM   10319 C CB  . ALA D 1 303 ? 129.752 121.356 164.894 1.00 81.30  ? 249 ALA D CB  1 
ATOM   10320 N N   . ARG D 1 304 ? 127.311 123.043 164.136 1.00 76.71  ? 250 ARG D N   1 
ATOM   10321 C CA  . ARG D 1 304 ? 125.993 123.147 163.522 1.00 78.02  ? 250 ARG D CA  1 
ATOM   10322 C C   . ARG D 1 304 ? 125.873 124.406 162.674 1.00 82.65  ? 250 ARG D C   1 
ATOM   10323 O O   . ARG D 1 304 ? 125.249 124.380 161.605 1.00 84.24  ? 250 ARG D O   1 
ATOM   10324 C CB  . ARG D 1 304 ? 124.912 123.101 164.600 1.00 77.70  ? 250 ARG D CB  1 
ATOM   10325 C CG  . ARG D 1 304 ? 124.928 121.808 165.398 1.00 82.03  ? 250 ARG D CG  1 
ATOM   10326 C CD  . ARG D 1 304 ? 123.754 121.709 166.352 1.00 86.13  ? 250 ARG D CD  1 
ATOM   10327 N NE  . ARG D 1 304 ? 122.478 121.681 165.648 1.00 83.87  ? 250 ARG D NE  1 
ATOM   10328 C CZ  . ARG D 1 304 ? 121.307 121.473 166.232 1.00 86.84  ? 250 ARG D CZ  1 
ATOM   10329 N NH1 . ARG D 1 304 ? 121.213 121.254 167.533 1.00 90.26  ? 250 ARG D NH1 1 
ATOM   10330 N NH2 . ARG D 1 304 ? 120.201 121.485 165.492 1.00 87.90  ? 250 ARG D NH2 1 
ATOM   10331 N N   . VAL D 1 305 ? 126.470 125.515 163.121 1.00 83.98  ? 251 VAL D N   1 
ATOM   10332 C CA  . VAL D 1 305 ? 126.437 126.743 162.328 1.00 80.11  ? 251 VAL D CA  1 
ATOM   10333 C C   . VAL D 1 305 ? 127.109 126.519 160.980 1.00 78.70  ? 251 VAL D C   1 
ATOM   10334 O O   . VAL D 1 305 ? 126.561 126.865 159.922 1.00 75.18  ? 251 VAL D O   1 
ATOM   10335 C CB  . VAL D 1 305 ? 127.099 127.899 163.098 1.00 77.31  ? 251 VAL D CB  1 
ATOM   10336 C CG1 . VAL D 1 305 ? 127.457 129.030 162.151 1.00 80.02  ? 251 VAL D CG1 1 
ATOM   10337 C CG2 . VAL D 1 305 ? 126.183 128.405 164.193 1.00 82.68  ? 251 VAL D CG2 1 
ATOM   10338 N N   . ALA D 1 306 ? 128.307 125.930 160.999 1.00 80.48  ? 252 ALA D N   1 
ATOM   10339 C CA  . ALA D 1 306 ? 129.034 125.689 159.759 1.00 78.00  ? 252 ALA D CA  1 
ATOM   10340 C C   . ALA D 1 306 ? 128.269 124.738 158.854 1.00 74.90  ? 252 ALA D C   1 
ATOM   10341 O O   . ALA D 1 306 ? 128.176 124.966 157.642 1.00 74.83  ? 252 ALA D O   1 
ATOM   10342 C CB  . ALA D 1 306 ? 130.426 125.137 160.064 1.00 75.98  ? 252 ALA D CB  1 
ATOM   10343 N N   . LEU D 1 307 ? 127.704 123.671 159.424 1.00 73.05  ? 253 LEU D N   1 
ATOM   10344 C CA  . LEU D 1 307 ? 126.965 122.716 158.608 1.00 73.59  ? 253 LEU D CA  1 
ATOM   10345 C C   . LEU D 1 307 ? 125.766 123.379 157.945 1.00 73.71  ? 253 LEU D C   1 
ATOM   10346 O O   . LEU D 1 307 ? 125.533 123.203 156.743 1.00 75.42  ? 253 LEU D O   1 
ATOM   10347 C CB  . LEU D 1 307 ? 126.536 121.519 159.458 1.00 71.38  ? 253 LEU D CB  1 
ATOM   10348 C CG  . LEU D 1 307 ? 126.120 120.264 158.687 1.00 70.64  ? 253 LEU D CG  1 
ATOM   10349 C CD1 . LEU D 1 307 ? 126.891 120.150 157.387 1.00 75.15  ? 253 LEU D CD1 1 
ATOM   10350 C CD2 . LEU D 1 307 ? 126.352 119.028 159.534 1.00 69.58  ? 253 LEU D CD2 1 
ATOM   10351 N N   . GLY D 1 308 ? 125.009 124.172 158.705 1.00 73.04  ? 254 GLY D N   1 
ATOM   10352 C CA  . GLY D 1 308 ? 123.849 124.833 158.130 1.00 74.37  ? 254 GLY D CA  1 
ATOM   10353 C C   . GLY D 1 308 ? 124.218 125.801 157.023 1.00 71.38  ? 254 GLY D C   1 
ATOM   10354 O O   . GLY D 1 308 ? 123.615 125.793 155.945 1.00 70.49  ? 254 GLY D O   1 
ATOM   10355 N N   . ILE D 1 309 ? 125.228 126.641 157.268 1.00 69.71  ? 255 ILE D N   1 
ATOM   10356 C CA  . ILE D 1 309 ? 125.614 127.637 156.270 1.00 68.68  ? 255 ILE D CA  1 
ATOM   10357 C C   . ILE D 1 309 ? 126.137 126.959 155.007 1.00 71.46  ? 255 ILE D C   1 
ATOM   10358 O O   . ILE D 1 309 ? 125.779 127.339 153.882 1.00 71.66  ? 255 ILE D O   1 
ATOM   10359 C CB  . ILE D 1 309 ? 126.645 128.612 156.865 1.00 64.96  ? 255 ILE D CB  1 
ATOM   10360 C CG1 . ILE D 1 309 ? 126.018 129.401 158.015 1.00 65.92  ? 255 ILE D CG1 1 
ATOM   10361 C CG2 . ILE D 1 309 ? 127.172 129.552 155.797 1.00 65.05  ? 255 ILE D CG2 1 
ATOM   10362 C CD1 . ILE D 1 309 ? 126.954 130.398 158.659 1.00 67.01  ? 255 ILE D CD1 1 
ATOM   10363 N N   . THR D 1 310 ? 126.992 125.945 155.172 1.00 70.46  ? 256 THR D N   1 
ATOM   10364 C CA  . THR D 1 310 ? 127.539 125.244 154.017 1.00 68.07  ? 256 THR D CA  1 
ATOM   10365 C C   . THR D 1 310 ? 126.445 124.540 153.227 1.00 70.42  ? 256 THR D C   1 
ATOM   10366 O O   . THR D 1 310 ? 126.462 124.552 151.992 1.00 69.58  ? 256 THR D O   1 
ATOM   10367 C CB  . THR D 1 310 ? 128.603 124.245 154.466 1.00 70.74  ? 256 THR D CB  1 
ATOM   10368 O OG1 . THR D 1 310 ? 128.091 123.459 155.550 1.00 74.68  ? 256 THR D OG1 1 
ATOM   10369 C CG2 . THR D 1 310 ? 129.857 124.974 154.919 1.00 71.76  ? 256 THR D CG2 1 
ATOM   10370 N N   . THR D 1 311 ? 125.487 123.916 153.918 1.00 71.52  ? 257 THR D N   1 
ATOM   10371 C CA  . THR D 1 311 ? 124.387 123.263 153.217 1.00 69.47  ? 257 THR D CA  1 
ATOM   10372 C C   . THR D 1 311 ? 123.556 124.276 152.442 1.00 72.16  ? 257 THR D C   1 
ATOM   10373 O O   . THR D 1 311 ? 123.155 124.020 151.302 1.00 72.79  ? 257 THR D O   1 
ATOM   10374 C CB  . THR D 1 311 ? 123.510 122.490 154.202 1.00 66.78  ? 257 THR D CB  1 
ATOM   10375 O OG1 . THR D 1 311 ? 123.239 123.305 155.348 1.00 73.76  ? 257 THR D OG1 1 
ATOM   10376 C CG2 . THR D 1 311 ? 124.199 121.208 154.638 1.00 67.26  ? 257 THR D CG2 1 
ATOM   10377 N N   . VAL D 1 312 ? 123.298 125.442 153.042 1.00 71.35  ? 258 VAL D N   1 
ATOM   10378 C CA  . VAL D 1 312 ? 122.519 126.470 152.353 1.00 71.40  ? 258 VAL D CA  1 
ATOM   10379 C C   . VAL D 1 312 ? 123.226 126.908 151.076 1.00 71.63  ? 258 VAL D C   1 
ATOM   10380 O O   . VAL D 1 312 ? 122.626 126.961 149.994 1.00 72.94  ? 258 VAL D O   1 
ATOM   10381 C CB  . VAL D 1 312 ? 122.257 127.664 153.289 1.00 70.86  ? 258 VAL D CB  1 
ATOM   10382 C CG1 . VAL D 1 312 ? 121.755 128.858 152.495 1.00 72.46  ? 258 VAL D CG1 1 
ATOM   10383 C CG2 . VAL D 1 312 ? 121.252 127.283 154.358 1.00 72.06  ? 258 VAL D CG2 1 
ATOM   10384 N N   . LEU D 1 313 ? 124.521 127.217 151.181 1.00 70.79  ? 259 LEU D N   1 
ATOM   10385 C CA  . LEU D 1 313 ? 125.251 127.695 150.009 1.00 70.96  ? 259 LEU D CA  1 
ATOM   10386 C C   . LEU D 1 313 ? 125.365 126.612 148.937 1.00 73.80  ? 259 LEU D C   1 
ATOM   10387 O O   . LEU D 1 313 ? 125.192 126.887 147.740 1.00 74.84  ? 259 LEU D O   1 
ATOM   10388 C CB  . LEU D 1 313 ? 126.632 128.200 150.425 1.00 67.88  ? 259 LEU D CB  1 
ATOM   10389 C CG  . LEU D 1 313 ? 126.619 129.298 151.493 1.00 60.31  ? 259 LEU D CG  1 
ATOM   10390 C CD1 . LEU D 1 313 ? 128.013 129.854 151.732 1.00 67.40  ? 259 LEU D CD1 1 
ATOM   10391 C CD2 . LEU D 1 313 ? 125.655 130.410 151.116 1.00 57.09  ? 259 LEU D CD2 1 
ATOM   10392 N N   . THR D 1 314 ? 125.638 125.370 149.346 1.00 69.21  ? 260 THR D N   1 
ATOM   10393 C CA  . THR D 1 314 ? 125.739 124.281 148.383 1.00 68.90  ? 260 THR D CA  1 
ATOM   10394 C C   . THR D 1 314 ? 124.408 124.043 147.684 1.00 71.52  ? 260 THR D C   1 
ATOM   10395 O O   . THR D 1 314 ? 124.372 123.750 146.483 1.00 79.41  ? 260 THR D O   1 
ATOM   10396 C CB  . THR D 1 314 ? 126.218 123.010 149.081 1.00 73.19  ? 260 THR D CB  1 
ATOM   10397 O OG1 . THR D 1 314 ? 127.326 123.325 149.931 1.00 78.85  ? 260 THR D OG1 1 
ATOM   10398 C CG2 . THR D 1 314 ? 126.658 121.979 148.057 1.00 77.99  ? 260 THR D CG2 1 
ATOM   10399 N N   . MET D 1 315 ? 123.300 124.161 148.419 1.00 65.59  ? 261 MET D N   1 
ATOM   10400 C CA  . MET D 1 315 ? 121.987 124.054 147.796 1.00 65.97  ? 261 MET D CA  1 
ATOM   10401 C C   . MET D 1 315 ? 121.762 125.177 146.794 1.00 71.27  ? 261 MET D C   1 
ATOM   10402 O O   . MET D 1 315 ? 121.203 124.952 145.714 1.00 76.58  ? 261 MET D O   1 
ATOM   10403 C CB  . MET D 1 315 ? 120.898 124.063 148.867 1.00 67.22  ? 261 MET D CB  1 
ATOM   10404 C CG  . MET D 1 315 ? 119.495 123.923 148.312 1.00 70.23  ? 261 MET D CG  1 
ATOM   10405 S SD  . MET D 1 315 ? 119.243 122.340 147.494 1.00 68.17  ? 261 MET D SD  1 
ATOM   10406 C CE  . MET D 1 315 ? 119.495 121.221 148.864 1.00 62.00  ? 261 MET D CE  1 
ATOM   10407 N N   . THR D 1 316 ? 122.188 126.397 147.133 1.00 74.93  ? 262 THR D N   1 
ATOM   10408 C CA  . THR D 1 316 ? 122.056 127.501 146.185 1.00 76.75  ? 262 THR D CA  1 
ATOM   10409 C C   . THR D 1 316 ? 122.877 127.262 144.925 1.00 77.55  ? 262 THR D C   1 
ATOM   10410 O O   . THR D 1 316 ? 122.514 127.747 143.848 1.00 80.77  ? 262 THR D O   1 
ATOM   10411 C CB  . THR D 1 316 ? 122.479 128.823 146.827 1.00 77.89  ? 262 THR D CB  1 
ATOM   10412 O OG1 . THR D 1 316 ? 123.833 128.724 147.281 1.00 78.36  ? 262 THR D OG1 1 
ATOM   10413 C CG2 . THR D 1 316 ? 121.573 129.170 147.993 1.00 76.20  ? 262 THR D CG2 1 
ATOM   10414 N N   . THR D 1 317 ? 123.979 126.525 145.036 1.00 77.19  ? 263 THR D N   1 
ATOM   10415 C CA  . THR D 1 317 ? 124.869 126.289 143.897 1.00 77.56  ? 263 THR D CA  1 
ATOM   10416 C C   . THR D 1 317 ? 124.680 124.908 143.274 1.00 77.53  ? 263 THR D C   1 
ATOM   10417 O O   . THR D 1 317 ? 125.664 124.238 142.949 1.00 80.17  ? 263 THR D O   1 
ATOM   10418 C CB  . THR D 1 317 ? 126.325 126.487 144.307 1.00 81.89  ? 263 THR D CB  1 
ATOM   10419 O OG1 . THR D 1 317 ? 126.693 125.492 145.270 1.00 85.77  ? 263 THR D OG1 1 
ATOM   10420 C CG2 . THR D 1 317 ? 126.524 127.870 144.910 1.00 81.93  ? 263 THR D CG2 1 
ATOM   10421 N N   . ILE D 1 318 ? 123.441 124.444 143.097 1.00 79.61  ? 264 ILE D N   1 
ATOM   10422 C CA  . ILE D 1 318 ? 123.206 123.103 142.564 1.00 85.15  ? 264 ILE D CA  1 
ATOM   10423 C C   . ILE D 1 318 ? 123.120 123.106 141.040 1.00 95.64  ? 264 ILE D C   1 
ATOM   10424 O O   . ILE D 1 318 ? 123.964 122.503 140.367 1.00 97.69  ? 264 ILE D O   1 
ATOM   10425 C CB  . ILE D 1 318 ? 121.941 122.476 143.177 1.00 80.44  ? 264 ILE D CB  1 
ATOM   10426 C CG1 . ILE D 1 318 ? 122.211 122.043 144.617 1.00 77.02  ? 264 ILE D CG1 1 
ATOM   10427 C CG2 . ILE D 1 318 ? 121.496 121.267 142.371 1.00 78.72  ? 264 ILE D CG2 1 
ATOM   10428 C CD1 . ILE D 1 318 ? 123.263 120.963 144.731 1.00 69.17  ? 264 ILE D CD1 1 
ATOM   10429 N N   . ASN D 1 319 ? 122.110 123.775 140.477 1.00 99.35  ? 265 ASN D N   1 
ATOM   10430 C CA  . ASN D 1 319 ? 121.844 123.707 139.043 1.00 100.45 ? 265 ASN D CA  1 
ATOM   10431 C C   . ASN D 1 319 ? 122.400 124.910 138.286 1.00 104.61 ? 265 ASN D C   1 
ATOM   10432 O O   . ASN D 1 319 ? 121.833 125.322 137.266 1.00 105.20 ? 265 ASN D O   1 
ATOM   10433 C CB  . ASN D 1 319 ? 120.346 123.553 138.777 1.00 100.53 ? 265 ASN D CB  1 
ATOM   10434 C CG  . ASN D 1 319 ? 119.568 124.831 139.028 1.00 111.12 ? 265 ASN D CG  1 
ATOM   10435 O OD1 . ASN D 1 319 ? 119.899 125.610 139.921 1.00 119.34 ? 265 ASN D OD1 1 
ATOM   10436 N ND2 . ASN D 1 319 ? 118.525 125.052 138.235 1.00 103.72 ? 265 ASN D ND2 1 
ATOM   10437 N N   . THR D 1 320 ? 123.506 125.478 138.766 1.00 102.81 ? 266 THR D N   1 
ATOM   10438 C CA  . THR D 1 320 ? 124.135 126.584 138.053 1.00 105.55 ? 266 THR D CA  1 
ATOM   10439 C C   . THR D 1 320 ? 124.610 126.142 136.674 1.00 109.86 ? 266 THR D C   1 
ATOM   10440 O O   . THR D 1 320 ? 124.489 126.891 135.697 1.00 112.67 ? 266 THR D O   1 
ATOM   10441 C CB  . THR D 1 320 ? 125.299 127.140 138.871 1.00 106.96 ? 266 THR D CB  1 
ATOM   10442 O OG1 . THR D 1 320 ? 124.838 127.487 140.182 1.00 98.94  ? 266 THR D OG1 1 
ATOM   10443 C CG2 . THR D 1 320 ? 125.879 128.376 138.204 1.00 114.31 ? 266 THR D CG2 1 
ATOM   10444 N N   . HIS D 1 321 ? 125.156 124.928 136.578 1.00 109.91 ? 267 HIS D N   1 
ATOM   10445 C CA  . HIS D 1 321 ? 125.586 124.407 135.285 1.00 114.55 ? 267 HIS D CA  1 
ATOM   10446 C C   . HIS D 1 321 ? 124.400 124.193 134.352 1.00 115.59 ? 267 HIS D C   1 
ATOM   10447 O O   . HIS D 1 321 ? 124.491 124.456 133.147 1.00 117.53 ? 267 HIS D O   1 
ATOM   10448 C CB  . HIS D 1 321 ? 126.359 123.102 135.477 1.00 115.66 ? 267 HIS D CB  1 
ATOM   10449 C CG  . HIS D 1 321 ? 125.483 121.907 135.692 1.00 115.60 ? 267 HIS D CG  1 
ATOM   10450 N ND1 . HIS D 1 321 ? 125.149 121.038 134.675 1.00 117.00 ? 267 HIS D ND1 1 
ATOM   10451 C CD2 . HIS D 1 321 ? 124.859 121.444 136.801 1.00 114.11 ? 267 HIS D CD2 1 
ATOM   10452 C CE1 . HIS D 1 321 ? 124.366 120.086 135.151 1.00 112.29 ? 267 HIS D CE1 1 
ATOM   10453 N NE2 . HIS D 1 321 ? 124.175 120.309 136.438 1.00 114.80 ? 267 HIS D NE2 1 
ATOM   10454 N N   . LEU D 1 322 ? 123.278 123.713 134.891 1.00 114.86 ? 268 LEU D N   1 
ATOM   10455 C CA  . LEU D 1 322 ? 122.112 123.407 134.074 1.00 114.56 ? 268 LEU D CA  1 
ATOM   10456 C C   . LEU D 1 322 ? 121.378 124.656 133.608 1.00 116.19 ? 268 LEU D C   1 
ATOM   10457 O O   . LEU D 1 322 ? 120.793 124.643 132.520 1.00 112.84 ? 268 LEU D O   1 
ATOM   10458 C CB  . LEU D 1 322 ? 121.154 122.502 134.853 1.00 110.88 ? 268 LEU D CB  1 
ATOM   10459 C CG  . LEU D 1 322 ? 119.975 121.899 134.090 1.00 102.61 ? 268 LEU D CG  1 
ATOM   10460 C CD1 . LEU D 1 322 ? 120.463 120.891 133.063 1.00 99.64  ? 268 LEU D CD1 1 
ATOM   10461 C CD2 . LEU D 1 322 ? 118.986 121.257 135.050 1.00 90.78  ? 268 LEU D CD2 1 
ATOM   10462 N N   . ARG D 1 323 ? 121.396 125.728 134.404 1.00 118.67 ? 269 ARG D N   1 
ATOM   10463 C CA  . ARG D 1 323 ? 120.714 126.957 134.007 1.00 120.66 ? 269 ARG D CA  1 
ATOM   10464 C C   . ARG D 1 323 ? 121.335 127.559 132.751 1.00 119.17 ? 269 ARG D C   1 
ATOM   10465 O O   . ARG D 1 323 ? 120.646 128.216 131.961 1.00 116.33 ? 269 ARG D O   1 
ATOM   10466 C CB  . ARG D 1 323 ? 120.740 127.967 135.156 1.00 122.21 ? 269 ARG D CB  1 
ATOM   10467 C CG  . ARG D 1 323 ? 120.144 129.324 134.808 1.00 126.48 ? 269 ARG D CG  1 
ATOM   10468 C CD  . ARG D 1 323 ? 120.187 130.289 135.982 1.00 130.74 ? 269 ARG D CD  1 
ATOM   10469 N NE  . ARG D 1 323 ? 119.285 129.889 137.056 1.00 135.84 ? 269 ARG D NE  1 
ATOM   10470 C CZ  . ARG D 1 323 ? 118.987 130.646 138.103 1.00 134.72 ? 269 ARG D CZ  1 
ATOM   10471 N NH1 . ARG D 1 323 ? 119.497 131.858 138.247 1.00 133.33 ? 269 ARG D NH1 1 
ATOM   10472 N NH2 . ARG D 1 323 ? 118.154 130.177 139.027 1.00 132.85 ? 269 ARG D NH2 1 
ATOM   10473 N N   . GLU D 1 324 ? 122.634 127.330 132.541 1.00 119.73 ? 270 GLU D N   1 
ATOM   10474 C CA  . GLU D 1 324 ? 123.338 127.971 131.434 1.00 119.66 ? 270 GLU D CA  1 
ATOM   10475 C C   . GLU D 1 324 ? 122.779 127.536 130.084 1.00 118.35 ? 270 GLU D C   1 
ATOM   10476 O O   . GLU D 1 324 ? 122.639 128.356 129.169 1.00 116.65 ? 270 GLU D O   1 
ATOM   10477 C CB  . GLU D 1 324 ? 124.831 127.663 131.523 1.00 122.90 ? 270 GLU D CB  1 
ATOM   10478 C CG  . GLU D 1 324 ? 125.485 128.150 132.806 1.00 125.70 ? 270 GLU D CG  1 
ATOM   10479 C CD  . GLU D 1 324 ? 126.916 127.670 132.953 1.00 133.82 ? 270 GLU D CD  1 
ATOM   10480 O OE1 . GLU D 1 324 ? 127.361 126.854 132.118 1.00 135.88 ? 270 GLU D OE1 1 
ATOM   10481 O OE2 . GLU D 1 324 ? 127.596 128.107 133.905 1.00 133.89 ? 270 GLU D OE2 1 
ATOM   10482 N N   . THR D 1 325 ? 122.451 126.253 129.939 1.00 121.22 ? 271 THR D N   1 
ATOM   10483 C CA  . THR D 1 325 ? 121.938 125.713 128.688 1.00 119.22 ? 271 THR D CA  1 
ATOM   10484 C C   . THR D 1 325 ? 120.414 125.665 128.647 1.00 113.29 ? 271 THR D C   1 
ATOM   10485 O O   . THR D 1 325 ? 119.848 124.771 128.006 1.00 108.90 ? 271 THR D O   1 
ATOM   10486 C CB  . THR D 1 325 ? 122.514 124.317 128.439 1.00 119.99 ? 271 THR D CB  1 
ATOM   10487 O OG1 . THR D 1 325 ? 122.247 123.479 129.570 1.00 121.18 ? 271 THR D OG1 1 
ATOM   10488 C CG2 . THR D 1 325 ? 124.016 124.394 128.210 1.00 118.33 ? 271 THR D CG2 1 
ATOM   10489 N N   . LEU D 1 326 ? 119.744 126.595 129.311 1.00 112.20 ? 272 LEU D N   1 
ATOM   10490 C CA  . LEU D 1 326 ? 118.294 126.674 129.356 1.00 105.17 ? 272 LEU D CA  1 
ATOM   10491 C C   . LEU D 1 326 ? 117.848 128.081 128.992 1.00 107.07 ? 272 LEU D C   1 
ATOM   10492 O O   . LEU D 1 326 ? 118.582 129.050 129.212 1.00 110.76 ? 272 LEU D O   1 
ATOM   10493 C CB  . LEU D 1 326 ? 117.769 126.296 130.749 1.00 101.12 ? 272 LEU D CB  1 
ATOM   10494 C CG  . LEU D 1 326 ? 117.835 124.801 131.063 1.00 100.57 ? 272 LEU D CG  1 
ATOM   10495 C CD1 . LEU D 1 326 ? 117.504 124.527 132.521 1.00 96.33  ? 272 LEU D CD1 1 
ATOM   10496 C CD2 . LEU D 1 326 ? 116.898 124.031 130.144 1.00 90.17  ? 272 LEU D CD2 1 
ATOM   10497 N N   . PRO D 1 327 ? 116.654 128.227 128.426 1.00 103.92 ? 273 PRO D N   1 
ATOM   10498 C CA  . PRO D 1 327 ? 116.192 129.539 127.972 1.00 103.16 ? 273 PRO D CA  1 
ATOM   10499 C C   . PRO D 1 327 ? 115.694 130.420 129.115 1.00 104.33 ? 273 PRO D C   1 
ATOM   10500 O O   . PRO D 1 327 ? 115.748 130.058 130.292 1.00 106.42 ? 273 PRO D O   1 
ATOM   10501 C CB  . PRO D 1 327 ? 115.042 129.186 127.019 1.00 96.80  ? 273 PRO D CB  1 
ATOM   10502 C CG  . PRO D 1 327 ? 114.515 127.905 127.548 1.00 94.16  ? 273 PRO D CG  1 
ATOM   10503 C CD  . PRO D 1 327 ? 115.710 127.154 128.065 1.00 98.93  ? 273 PRO D CD  1 
ATOM   10504 N N   . LYS D 1 328 ? 115.204 131.599 128.731 1.00 101.03 ? 274 LYS D N   1 
ATOM   10505 C CA  . LYS D 1 328 ? 114.621 132.557 129.665 1.00 99.02  ? 274 LYS D CA  1 
ATOM   10506 C C   . LYS D 1 328 ? 113.101 132.493 129.602 1.00 94.52  ? 274 LYS D C   1 
ATOM   10507 O O   . LYS D 1 328 ? 112.430 133.529 129.614 1.00 94.44  ? 274 LYS D O   1 
ATOM   10508 C CB  . LYS D 1 328 ? 115.090 133.979 129.353 1.00 102.68 ? 274 LYS D CB  1 
ATOM   10509 C CG  . LYS D 1 328 ? 116.592 134.184 129.370 1.00 104.79 ? 274 LYS D CG  1 
ATOM   10510 C CD  . LYS D 1 328 ? 116.929 135.629 129.038 1.00 109.65 ? 274 LYS D CD  1 
ATOM   10511 C CE  . LYS D 1 328 ? 118.425 135.871 129.031 1.00 116.83 ? 274 LYS D CE  1 
ATOM   10512 N NZ  . LYS D 1 328 ? 118.743 137.294 128.730 1.00 120.49 ? 274 LYS D NZ  1 
ATOM   10513 N N   . ILE D 1 329 ? 112.558 131.283 129.521 1.00 91.39  ? 275 ILE D N   1 
ATOM   10514 C CA  . ILE D 1 329 ? 111.126 131.059 129.339 1.00 87.06  ? 275 ILE D CA  1 
ATOM   10515 C C   . ILE D 1 329 ? 110.341 131.693 130.482 1.00 90.73  ? 275 ILE D C   1 
ATOM   10516 O O   . ILE D 1 329 ? 110.756 131.603 131.647 1.00 94.19  ? 275 ILE D O   1 
ATOM   10517 C CB  . ILE D 1 329 ? 110.821 129.559 129.226 1.00 86.10  ? 275 ILE D CB  1 
ATOM   10518 C CG1 . ILE D 1 329 ? 111.706 128.772 130.195 1.00 86.87  ? 275 ILE D CG1 1 
ATOM   10519 C CG2 . ILE D 1 329 ? 111.012 129.087 127.793 1.00 88.63  ? 275 ILE D CG2 1 
ATOM   10520 C CD1 . ILE D 1 329 ? 111.650 127.277 130.004 1.00 87.76  ? 275 ILE D CD1 1 
ATOM   10521 N N   . PRO D 1 330 ? 109.199 132.340 130.196 1.00 90.51  ? 276 PRO D N   1 
ATOM   10522 C CA  . PRO D 1 330 ? 108.424 133.058 131.216 1.00 90.36  ? 276 PRO D CA  1 
ATOM   10523 C C   . PRO D 1 330 ? 107.544 132.155 132.078 1.00 91.91  ? 276 PRO D C   1 
ATOM   10524 O O   . PRO D 1 330 ? 106.362 132.431 132.293 1.00 91.98  ? 276 PRO D O   1 
ATOM   10525 C CB  . PRO D 1 330 ? 107.580 134.019 130.375 1.00 91.52  ? 276 PRO D CB  1 
ATOM   10526 C CG  . PRO D 1 330 ? 107.321 133.244 129.136 1.00 90.74  ? 276 PRO D CG  1 
ATOM   10527 C CD  . PRO D 1 330 ? 108.592 132.474 128.861 1.00 87.93  ? 276 PRO D CD  1 
ATOM   10528 N N   . TYR D 1 331 ? 108.124 131.068 132.574 1.00 91.23  ? 277 TYR D N   1 
ATOM   10529 C CA  . TYR D 1 331 ? 107.414 130.162 133.465 1.00 83.26  ? 277 TYR D CA  1 
ATOM   10530 C C   . TYR D 1 331 ? 108.439 129.341 134.231 1.00 82.31  ? 277 TYR D C   1 
ATOM   10531 O O   . TYR D 1 331 ? 109.625 129.317 133.893 1.00 85.35  ? 277 TYR D O   1 
ATOM   10532 C CB  . TYR D 1 331 ? 106.432 129.265 132.702 1.00 83.96  ? 277 TYR D CB  1 
ATOM   10533 C CG  . TYR D 1 331 ? 107.009 128.591 131.478 1.00 85.51  ? 277 TYR D CG  1 
ATOM   10534 C CD1 . TYR D 1 331 ? 107.668 127.375 131.577 1.00 80.05  ? 277 TYR D CD1 1 
ATOM   10535 C CD2 . TYR D 1 331 ? 106.878 129.163 130.221 1.00 87.78  ? 277 TYR D CD2 1 
ATOM   10536 C CE1 . TYR D 1 331 ? 108.189 126.755 130.463 1.00 81.05  ? 277 TYR D CE1 1 
ATOM   10537 C CE2 . TYR D 1 331 ? 107.396 128.548 129.100 1.00 87.96  ? 277 TYR D CE2 1 
ATOM   10538 C CZ  . TYR D 1 331 ? 108.051 127.344 129.227 1.00 87.05  ? 277 TYR D CZ  1 
ATOM   10539 O OH  . TYR D 1 331 ? 108.570 126.726 128.113 1.00 90.29  ? 277 TYR D OH  1 
ATOM   10540 N N   . VAL D 1 332 ? 107.965 128.672 135.275 1.00 78.16  ? 278 VAL D N   1 
ATOM   10541 C CA  . VAL D 1 332 ? 108.817 127.924 136.189 1.00 73.41  ? 278 VAL D CA  1 
ATOM   10542 C C   . VAL D 1 332 ? 108.787 126.453 135.803 1.00 72.84  ? 278 VAL D C   1 
ATOM   10543 O O   . VAL D 1 332 ? 107.711 125.865 135.642 1.00 74.25  ? 278 VAL D O   1 
ATOM   10544 C CB  . VAL D 1 332 ? 108.373 128.122 137.648 1.00 70.43  ? 278 VAL D CB  1 
ATOM   10545 C CG1 . VAL D 1 332 ? 109.151 127.199 138.565 1.00 78.36  ? 278 VAL D CG1 1 
ATOM   10546 C CG2 . VAL D 1 332 ? 108.567 129.570 138.060 1.00 72.12  ? 278 VAL D CG2 1 
ATOM   10547 N N   . LYS D 1 333 ? 109.967 125.864 135.647 0.50 69.08  ? 279 LYS D N   1 
ATOM   10548 C CA  . LYS D 1 333 ? 110.112 124.452 135.336 0.50 68.56  ? 279 LYS D CA  1 
ATOM   10549 C C   . LYS D 1 333 ? 110.082 123.621 136.615 0.50 69.37  ? 279 LYS D C   1 
ATOM   10550 O O   . LYS D 1 333 ? 110.277 124.130 137.721 0.50 69.82  ? 279 LYS D O   1 
ATOM   10551 C CB  . LYS D 1 333 ? 111.414 124.209 134.576 1.00 67.53  ? 279 LYS D CB  1 
ATOM   10552 C CG  . LYS D 1 333 ? 111.510 124.976 133.271 1.00 69.27  ? 279 LYS D CG  1 
ATOM   10553 C CD  . LYS D 1 333 ? 112.955 125.231 132.888 1.00 73.88  ? 279 LYS D CD  1 
ATOM   10554 C CE  . LYS D 1 333 ? 113.644 126.104 133.922 1.00 71.97  ? 279 LYS D CE  1 
ATOM   10555 N NZ  . LYS D 1 333 ? 115.034 126.452 133.524 1.00 75.72  ? 279 LYS D NZ  1 
ATOM   10556 N N   . ALA D 1 334 ? 109.831 122.320 136.446 1.00 64.54  ? 280 ALA D N   1 
ATOM   10557 C CA  . ALA D 1 334 ? 109.708 121.433 137.600 1.00 58.54  ? 280 ALA D CA  1 
ATOM   10558 C C   . ALA D 1 334 ? 111.010 121.356 138.389 1.00 62.17  ? 280 ALA D C   1 
ATOM   10559 O O   . ALA D 1 334 ? 110.993 121.267 139.623 1.00 70.12  ? 280 ALA D O   1 
ATOM   10560 C CB  . ALA D 1 334 ? 109.273 120.041 137.149 1.00 58.82  ? 280 ALA D CB  1 
ATOM   10561 N N   . ILE D 1 335 ? 112.148 121.378 137.694 1.00 61.75  ? 281 ILE D N   1 
ATOM   10562 C CA  . ILE D 1 335 ? 113.435 121.349 138.383 1.00 66.97  ? 281 ILE D CA  1 
ATOM   10563 C C   . ILE D 1 335 ? 113.574 122.563 139.293 1.00 72.78  ? 281 ILE D C   1 
ATOM   10564 O O   . ILE D 1 335 ? 114.083 122.463 140.418 1.00 77.33  ? 281 ILE D O   1 
ATOM   10565 C CB  . ILE D 1 335 ? 114.585 121.258 137.361 1.00 65.30  ? 281 ILE D CB  1 
ATOM   10566 C CG1 . ILE D 1 335 ? 115.941 121.409 138.053 1.00 73.21  ? 281 ILE D CG1 1 
ATOM   10567 C CG2 . ILE D 1 335 ? 114.417 122.295 136.263 1.00 65.86  ? 281 ILE D CG2 1 
ATOM   10568 C CD1 . ILE D 1 335 ? 116.280 120.275 138.992 1.00 70.64  ? 281 ILE D CD1 1 
ATOM   10569 N N   . ASP D 1 336 ? 113.105 123.724 138.829 1.00 70.59  ? 282 ASP D N   1 
ATOM   10570 C CA  . ASP D 1 336 ? 113.143 124.923 139.659 1.00 71.87  ? 282 ASP D CA  1 
ATOM   10571 C C   . ASP D 1 336 ? 112.300 124.747 140.914 1.00 70.01  ? 282 ASP D C   1 
ATOM   10572 O O   . ASP D 1 336 ? 112.716 125.143 142.008 1.00 73.64  ? 282 ASP D O   1 
ATOM   10573 C CB  . ASP D 1 336 ? 112.663 126.134 138.859 1.00 80.75  ? 282 ASP D CB  1 
ATOM   10574 C CG  . ASP D 1 336 ? 113.467 126.354 137.593 1.00 86.39  ? 282 ASP D CG  1 
ATOM   10575 O OD1 . ASP D 1 336 ? 114.281 125.474 137.245 1.00 90.21  ? 282 ASP D OD1 1 
ATOM   10576 O OD2 . ASP D 1 336 ? 113.288 127.409 136.948 1.00 81.96  ? 282 ASP D OD2 1 
ATOM   10577 N N   . MET D 1 337 ? 111.111 124.153 140.778 1.00 66.04  ? 283 MET D N   1 
ATOM   10578 C CA  . MET D 1 337 ? 110.256 123.930 141.939 1.00 68.78  ? 283 MET D CA  1 
ATOM   10579 C C   . MET D 1 337 ? 110.909 122.984 142.939 1.00 67.47  ? 283 MET D C   1 
ATOM   10580 O O   . MET D 1 337 ? 110.870 123.226 144.152 1.00 70.09  ? 283 MET D O   1 
ATOM   10581 C CB  . MET D 1 337 ? 108.900 123.382 141.495 1.00 63.25  ? 283 MET D CB  1 
ATOM   10582 C CG  . MET D 1 337 ? 108.048 124.379 140.735 1.00 65.43  ? 283 MET D CG  1 
ATOM   10583 S SD  . MET D 1 337 ? 107.666 125.828 141.733 1.00 94.34  ? 283 MET D SD  1 
ATOM   10584 C CE  . MET D 1 337 ? 106.933 125.053 143.172 1.00 76.18  ? 283 MET D CE  1 
ATOM   10585 N N   . TYR D 1 338 ? 111.512 121.898 142.451 1.00 65.84  ? 284 TYR D N   1 
ATOM   10586 C CA  . TYR D 1 338 ? 112.156 120.953 143.358 1.00 63.92  ? 284 TYR D CA  1 
ATOM   10587 C C   . TYR D 1 338 ? 113.330 121.601 144.082 1.00 65.66  ? 284 TYR D C   1 
ATOM   10588 O O   . TYR D 1 338 ? 113.509 121.409 145.293 1.00 72.15  ? 284 TYR D O   1 
ATOM   10589 C CB  . TYR D 1 338 ? 112.611 119.713 142.590 1.00 62.80  ? 284 TYR D CB  1 
ATOM   10590 C CG  . TYR D 1 338 ? 112.989 118.545 143.473 1.00 64.47  ? 284 TYR D CG  1 
ATOM   10591 C CD1 . TYR D 1 338 ? 112.034 117.630 143.893 1.00 66.88  ? 284 TYR D CD1 1 
ATOM   10592 C CD2 . TYR D 1 338 ? 114.301 118.353 143.881 1.00 60.06  ? 284 TYR D CD2 1 
ATOM   10593 C CE1 . TYR D 1 338 ? 112.375 116.561 144.697 1.00 65.93  ? 284 TYR D CE1 1 
ATOM   10594 C CE2 . TYR D 1 338 ? 114.650 117.287 144.684 1.00 59.87  ? 284 TYR D CE2 1 
ATOM   10595 C CZ  . TYR D 1 338 ? 113.684 116.395 145.088 1.00 65.84  ? 284 TYR D CZ  1 
ATOM   10596 O OH  . TYR D 1 338 ? 114.029 115.332 145.888 1.00 78.55  ? 284 TYR D OH  1 
ATOM   10597 N N   . LEU D 1 339 ? 114.137 122.382 143.360 1.00 63.33  ? 285 LEU D N   1 
ATOM   10598 C CA  . LEU D 1 339 ? 115.267 123.046 144.001 1.00 63.73  ? 285 LEU D CA  1 
ATOM   10599 C C   . LEU D 1 339 ? 114.801 124.095 145.001 1.00 68.92  ? 285 LEU D C   1 
ATOM   10600 O O   . LEU D 1 339 ? 115.413 124.258 146.063 1.00 74.10  ? 285 LEU D O   1 
ATOM   10601 C CB  . LEU D 1 339 ? 116.183 123.672 142.953 1.00 67.07  ? 285 LEU D CB  1 
ATOM   10602 C CG  . LEU D 1 339 ? 117.031 122.702 142.131 1.00 76.59  ? 285 LEU D CG  1 
ATOM   10603 C CD1 . LEU D 1 339 ? 118.357 123.345 141.792 1.00 80.72  ? 285 LEU D CD1 1 
ATOM   10604 C CD2 . LEU D 1 339 ? 117.249 121.389 142.867 1.00 71.04  ? 285 LEU D CD2 1 
ATOM   10605 N N   . MET D 1 340 ? 113.725 124.819 144.684 1.00 68.08  ? 286 MET D N   1 
ATOM   10606 C CA  . MET D 1 340 ? 113.187 125.790 145.629 1.00 67.31  ? 286 MET D CA  1 
ATOM   10607 C C   . MET D 1 340 ? 112.686 125.104 146.892 1.00 69.54  ? 286 MET D C   1 
ATOM   10608 O O   . MET D 1 340 ? 112.906 125.598 148.003 1.00 72.70  ? 286 MET D O   1 
ATOM   10609 C CB  . MET D 1 340 ? 112.069 126.602 144.978 1.00 63.92  ? 286 MET D CB  1 
ATOM   10610 C CG  . MET D 1 340 ? 112.556 127.655 143.998 1.00 72.86  ? 286 MET D CG  1 
ATOM   10611 S SD  . MET D 1 340 ? 111.216 128.643 143.307 1.00 93.87  ? 286 MET D SD  1 
ATOM   10612 C CE  . MET D 1 340 ? 112.136 129.785 142.282 1.00 79.09  ? 286 MET D CE  1 
ATOM   10613 N N   . GLY D 1 341 ? 112.016 123.960 146.743 1.00 65.74  ? 287 GLY D N   1 
ATOM   10614 C CA  . GLY D 1 341 ? 111.586 123.213 147.915 1.00 65.96  ? 287 GLY D CA  1 
ATOM   10615 C C   . GLY D 1 341 ? 112.749 122.744 148.770 1.00 70.25  ? 287 GLY D C   1 
ATOM   10616 O O   . GLY D 1 341 ? 112.715 122.853 150.000 1.00 74.55  ? 287 GLY D O   1 
ATOM   10617 N N   . CYS D 1 342 ? 113.795 122.214 148.132 1.00 69.89  ? 288 CYS D N   1 
ATOM   10618 C CA  . CYS D 1 342 ? 114.962 121.764 148.888 1.00 67.03  ? 288 CYS D CA  1 
ATOM   10619 C C   . CYS D 1 342 ? 115.647 122.926 149.600 1.00 71.11  ? 288 CYS D C   1 
ATOM   10620 O O   . CYS D 1 342 ? 116.085 122.792 150.752 1.00 77.74  ? 288 CYS D O   1 
ATOM   10621 C CB  . CYS D 1 342 ? 115.940 121.043 147.963 1.00 63.22  ? 288 CYS D CB  1 
ATOM   10622 S SG  . CYS D 1 342 ? 115.356 119.442 147.374 1.00 78.74  ? 288 CYS D SG  1 
ATOM   10623 N N   . PHE D 1 343 ? 115.759 124.074 148.925 1.00 67.41  ? 289 PHE D N   1 
ATOM   10624 C CA  . PHE D 1 343 ? 116.343 125.250 149.559 1.00 69.14  ? 289 PHE D CA  1 
ATOM   10625 C C   . PHE D 1 343 ? 115.501 125.707 150.741 1.00 72.44  ? 289 PHE D C   1 
ATOM   10626 O O   . PHE D 1 343 ? 116.040 126.100 151.783 1.00 76.28  ? 289 PHE D O   1 
ATOM   10627 C CB  . PHE D 1 343 ? 116.497 126.378 148.540 1.00 67.72  ? 289 PHE D CB  1 
ATOM   10628 C CG  . PHE D 1 343 ? 116.946 127.677 149.142 1.00 74.84  ? 289 PHE D CG  1 
ATOM   10629 C CD1 . PHE D 1 343 ? 118.282 127.898 149.427 1.00 77.70  ? 289 PHE D CD1 1 
ATOM   10630 C CD2 . PHE D 1 343 ? 116.032 128.677 149.424 1.00 75.94  ? 289 PHE D CD2 1 
ATOM   10631 C CE1 . PHE D 1 343 ? 118.696 129.091 149.984 1.00 81.23  ? 289 PHE D CE1 1 
ATOM   10632 C CE2 . PHE D 1 343 ? 116.440 129.872 149.981 1.00 78.21  ? 289 PHE D CE2 1 
ATOM   10633 C CZ  . PHE D 1 343 ? 117.774 130.080 150.259 1.00 82.19  ? 289 PHE D CZ  1 
ATOM   10634 N N   . VAL D 1 344 ? 114.176 125.667 150.595 1.00 68.91  ? 290 VAL D N   1 
ATOM   10635 C CA  . VAL D 1 344 ? 113.298 126.017 151.705 1.00 70.31  ? 290 VAL D CA  1 
ATOM   10636 C C   . VAL D 1 344 ? 113.543 125.089 152.885 1.00 72.66  ? 290 VAL D C   1 
ATOM   10637 O O   . VAL D 1 344 ? 113.634 125.534 154.034 1.00 74.90  ? 290 VAL D O   1 
ATOM   10638 C CB  . VAL D 1 344 ? 111.827 125.988 151.250 1.00 62.81  ? 290 VAL D CB  1 
ATOM   10639 C CG1 . VAL D 1 344 ? 110.898 125.940 152.450 1.00 62.19  ? 290 VAL D CG1 1 
ATOM   10640 C CG2 . VAL D 1 344 ? 111.522 127.203 150.396 1.00 59.75  ? 290 VAL D CG2 1 
ATOM   10641 N N   . PHE D 1 345 ? 113.671 123.787 152.621 1.00 67.99  ? 291 PHE D N   1 
ATOM   10642 C CA  . PHE D 1 345 ? 113.881 122.840 153.713 1.00 67.63  ? 291 PHE D CA  1 
ATOM   10643 C C   . PHE D 1 345 ? 115.211 123.076 154.421 1.00 69.91  ? 291 PHE D C   1 
ATOM   10644 O O   . PHE D 1 345 ? 115.270 123.067 155.658 1.00 78.00  ? 291 PHE D O   1 
ATOM   10645 C CB  . PHE D 1 345 ? 113.795 121.407 153.195 1.00 64.62  ? 291 PHE D CB  1 
ATOM   10646 C CG  . PHE D 1 345 ? 112.428 120.806 153.323 1.00 68.89  ? 291 PHE D CG  1 
ATOM   10647 C CD1 . PHE D 1 345 ? 112.026 120.222 154.510 1.00 70.06  ? 291 PHE D CD1 1 
ATOM   10648 C CD2 . PHE D 1 345 ? 111.544 120.833 152.261 1.00 77.50  ? 291 PHE D CD2 1 
ATOM   10649 C CE1 . PHE D 1 345 ? 110.770 119.672 154.634 1.00 77.37  ? 291 PHE D CE1 1 
ATOM   10650 C CE2 . PHE D 1 345 ? 110.285 120.284 152.378 1.00 78.22  ? 291 PHE D CE2 1 
ATOM   10651 C CZ  . PHE D 1 345 ? 109.897 119.702 153.566 1.00 79.85  ? 291 PHE D CZ  1 
ATOM   10652 N N   . VAL D 1 346 ? 116.290 123.292 153.666 1.00 66.71  ? 292 VAL D N   1 
ATOM   10653 C CA  . VAL D 1 346 ? 117.586 123.478 154.316 1.00 69.91  ? 292 VAL D CA  1 
ATOM   10654 C C   . VAL D 1 346 ? 117.622 124.801 155.079 1.00 77.50  ? 292 VAL D C   1 
ATOM   10655 O O   . VAL D 1 346 ? 118.183 124.884 156.183 1.00 84.46  ? 292 VAL D O   1 
ATOM   10656 C CB  . VAL D 1 346 ? 118.736 123.364 153.296 1.00 67.49  ? 292 VAL D CB  1 
ATOM   10657 C CG1 . VAL D 1 346 ? 118.732 121.988 152.654 1.00 69.01  ? 292 VAL D CG1 1 
ATOM   10658 C CG2 . VAL D 1 346 ? 118.645 124.444 152.238 1.00 69.66  ? 292 VAL D CG2 1 
ATOM   10659 N N   . PHE D 1 347 ? 117.011 125.851 154.521 1.00 74.79  ? 293 PHE D N   1 
ATOM   10660 C CA  . PHE D 1 347 ? 116.958 127.127 155.223 1.00 75.35  ? 293 PHE D CA  1 
ATOM   10661 C C   . PHE D 1 347 ? 116.122 127.019 156.491 1.00 76.08  ? 293 PHE D C   1 
ATOM   10662 O O   . PHE D 1 347 ? 116.449 127.631 157.514 1.00 78.40  ? 293 PHE D O   1 
ATOM   10663 C CB  . PHE D 1 347 ? 116.408 128.208 154.295 1.00 74.23  ? 293 PHE D CB  1 
ATOM   10664 C CG  . PHE D 1 347 ? 116.471 129.587 154.872 1.00 79.68  ? 293 PHE D CG  1 
ATOM   10665 C CD1 . PHE D 1 347 ? 117.684 130.244 154.994 1.00 82.62  ? 293 PHE D CD1 1 
ATOM   10666 C CD2 . PHE D 1 347 ? 115.321 130.231 155.290 1.00 78.07  ? 293 PHE D CD2 1 
ATOM   10667 C CE1 . PHE D 1 347 ? 117.749 131.514 155.526 1.00 82.01  ? 293 PHE D CE1 1 
ATOM   10668 C CE2 . PHE D 1 347 ? 115.378 131.503 155.820 1.00 84.05  ? 293 PHE D CE2 1 
ATOM   10669 C CZ  . PHE D 1 347 ? 116.595 132.145 155.940 1.00 84.09  ? 293 PHE D CZ  1 
ATOM   10670 N N   . LEU D 1 348 ? 115.041 126.237 156.447 1.00 71.95  ? 294 LEU D N   1 
ATOM   10671 C CA  . LEU D 1 348 ? 114.240 126.019 157.645 1.00 76.46  ? 294 LEU D CA  1 
ATOM   10672 C C   . LEU D 1 348 ? 115.018 125.237 158.696 1.00 77.39  ? 294 LEU D C   1 
ATOM   10673 O O   . LEU D 1 348 ? 114.879 125.500 159.894 1.00 81.54  ? 294 LEU D O   1 
ATOM   10674 C CB  . LEU D 1 348 ? 112.941 125.300 157.288 1.00 76.67  ? 294 LEU D CB  1 
ATOM   10675 C CG  . LEU D 1 348 ? 111.874 126.171 156.624 1.00 72.03  ? 294 LEU D CG  1 
ATOM   10676 C CD1 . LEU D 1 348 ? 110.618 125.365 156.341 1.00 77.40  ? 294 LEU D CD1 1 
ATOM   10677 C CD2 . LEU D 1 348 ? 111.558 127.366 157.501 1.00 71.86  ? 294 LEU D CD2 1 
ATOM   10678 N N   . ALA D 1 349 ? 115.832 124.269 158.272 1.00 76.29  ? 295 ALA D N   1 
ATOM   10679 C CA  . ALA D 1 349 ? 116.689 123.567 159.225 1.00 74.67  ? 295 ALA D CA  1 
ATOM   10680 C C   . ALA D 1 349 ? 117.658 124.530 159.903 1.00 73.34  ? 295 ALA D C   1 
ATOM   10681 O O   . ALA D 1 349 ? 117.836 124.495 161.132 1.00 75.57  ? 295 ALA D O   1 
ATOM   10682 C CB  . ALA D 1 349 ? 117.455 122.450 158.518 1.00 71.48  ? 295 ALA D CB  1 
ATOM   10683 N N   . LEU D 1 350 ? 118.284 125.406 159.114 1.00 70.77  ? 296 LEU D N   1 
ATOM   10684 C CA  . LEU D 1 350 ? 119.199 126.388 159.687 1.00 73.78  ? 296 LEU D CA  1 
ATOM   10685 C C   . LEU D 1 350 ? 118.479 127.314 160.661 1.00 80.92  ? 296 LEU D C   1 
ATOM   10686 O O   . LEU D 1 350 ? 118.997 127.613 161.743 1.00 83.47  ? 296 LEU D O   1 
ATOM   10687 C CB  . LEU D 1 350 ? 119.871 127.193 158.578 1.00 72.39  ? 296 LEU D CB  1 
ATOM   10688 C CG  . LEU D 1 350 ? 120.733 128.369 159.041 1.00 70.12  ? 296 LEU D CG  1 
ATOM   10689 C CD1 . LEU D 1 350 ? 121.845 127.886 159.955 1.00 67.88  ? 296 LEU D CD1 1 
ATOM   10690 C CD2 . LEU D 1 350 ? 121.304 129.123 157.852 1.00 73.09  ? 296 LEU D CD2 1 
ATOM   10691 N N   . LEU D 1 351 ? 117.280 127.778 160.295 1.00 82.10  ? 297 LEU D N   1 
ATOM   10692 C CA  . LEU D 1 351 ? 116.531 128.662 161.183 1.00 80.79  ? 297 LEU D CA  1 
ATOM   10693 C C   . LEU D 1 351 ? 116.107 127.946 162.459 1.00 83.52  ? 297 LEU D C   1 
ATOM   10694 O O   . LEU D 1 351 ? 116.095 128.548 163.538 1.00 92.07  ? 297 LEU D O   1 
ATOM   10695 C CB  . LEU D 1 351 ? 115.309 129.231 160.465 1.00 76.56  ? 297 LEU D CB  1 
ATOM   10696 C CG  . LEU D 1 351 ? 115.576 130.202 159.318 1.00 79.46  ? 297 LEU D CG  1 
ATOM   10697 C CD1 . LEU D 1 351 ? 114.363 131.088 159.103 1.00 86.00  ? 297 LEU D CD1 1 
ATOM   10698 C CD2 . LEU D 1 351 ? 116.819 131.037 159.585 1.00 77.08  ? 297 LEU D CD2 1 
ATOM   10699 N N   . GLU D 1 352 ? 115.730 126.671 162.352 1.00 81.87  ? 298 GLU D N   1 
ATOM   10700 C CA  . GLU D 1 352 ? 115.386 125.897 163.539 1.00 83.46  ? 298 GLU D CA  1 
ATOM   10701 C C   . GLU D 1 352 ? 116.568 125.829 164.491 1.00 85.46  ? 298 GLU D C   1 
ATOM   10702 O O   . GLU D 1 352 ? 116.425 126.060 165.698 1.00 88.51  ? 298 GLU D O   1 
ATOM   10703 C CB  . GLU D 1 352 ? 114.931 124.493 163.137 1.00 83.69  ? 298 GLU D CB  1 
ATOM   10704 C CG  . GLU D 1 352 ? 114.486 123.605 164.297 1.00 88.46  ? 298 GLU D CG  1 
ATOM   10705 C CD  . GLU D 1 352 ? 115.629 122.830 164.934 1.00 93.18  ? 298 GLU D CD  1 
ATOM   10706 O OE1 . GLU D 1 352 ? 116.764 122.899 164.419 1.00 89.83  ? 298 GLU D OE1 1 
ATOM   10707 O OE2 . GLU D 1 352 ? 115.392 122.150 165.954 1.00 97.92  ? 298 GLU D OE2 1 
ATOM   10708 N N   . TYR D 1 353 ? 117.755 125.522 163.961 1.00 85.45  ? 299 TYR D N   1 
ATOM   10709 C CA  . TYR D 1 353 ? 118.928 125.496 164.827 1.00 85.45  ? 299 TYR D CA  1 
ATOM   10710 C C   . TYR D 1 353 ? 119.213 126.872 165.416 1.00 89.53  ? 299 TYR D C   1 
ATOM   10711 O O   . TYR D 1 353 ? 119.616 126.983 166.579 1.00 96.95  ? 299 TYR D O   1 
ATOM   10712 C CB  . TYR D 1 353 ? 120.161 124.992 164.084 1.00 88.41  ? 299 TYR D CB  1 
ATOM   10713 C CG  . TYR D 1 353 ? 121.409 125.345 164.851 1.00 90.11  ? 299 TYR D CG  1 
ATOM   10714 C CD1 . TYR D 1 353 ? 121.686 124.739 166.068 1.00 90.75  ? 299 TYR D CD1 1 
ATOM   10715 C CD2 . TYR D 1 353 ? 122.279 126.320 164.390 1.00 89.42  ? 299 TYR D CD2 1 
ATOM   10716 C CE1 . TYR D 1 353 ? 122.807 125.072 166.789 1.00 92.67  ? 299 TYR D CE1 1 
ATOM   10717 C CE2 . TYR D 1 353 ? 123.402 126.658 165.106 1.00 91.61  ? 299 TYR D CE2 1 
ATOM   10718 C CZ  . TYR D 1 353 ? 123.661 126.031 166.302 1.00 94.07  ? 299 TYR D CZ  1 
ATOM   10719 O OH  . TYR D 1 353 ? 124.781 126.367 167.016 1.00 94.62  ? 299 TYR D OH  1 
ATOM   10720 N N   . ALA D 1 354 ? 119.041 127.929 164.621 1.00 86.15  ? 300 ALA D N   1 
ATOM   10721 C CA  . ALA D 1 354 ? 119.309 129.276 165.116 1.00 87.24  ? 300 ALA D CA  1 
ATOM   10722 C C   . ALA D 1 354 ? 118.381 129.627 166.272 1.00 94.14  ? 300 ALA D C   1 
ATOM   10723 O O   . ALA D 1 354 ? 118.812 130.195 167.282 1.00 94.50  ? 300 ALA D O   1 
ATOM   10724 C CB  . ALA D 1 354 ? 119.169 130.290 163.981 1.00 80.97  ? 300 ALA D CB  1 
ATOM   10725 N N   . PHE D 1 355 ? 117.100 129.285 166.142 1.00 94.62  ? 301 PHE D N   1 
ATOM   10726 C CA  . PHE D 1 355 ? 116.148 129.531 167.220 1.00 93.31  ? 301 PHE D CA  1 
ATOM   10727 C C   . PHE D 1 355 ? 116.485 128.701 168.453 1.00 97.52  ? 301 PHE D C   1 
ATOM   10728 O O   . PHE D 1 355 ? 116.371 129.181 169.590 1.00 102.98 ? 301 PHE D O   1 
ATOM   10729 C CB  . PHE D 1 355 ? 114.730 129.235 166.733 1.00 93.14  ? 301 PHE D CB  1 
ATOM   10730 C CG  . PHE D 1 355 ? 113.664 129.572 167.730 1.00 103.85 ? 301 PHE D CG  1 
ATOM   10731 C CD1 . PHE D 1 355 ? 113.664 130.796 168.376 1.00 109.55 ? 301 PHE D CD1 1 
ATOM   10732 C CD2 . PHE D 1 355 ? 112.650 128.671 168.009 1.00 105.56 ? 301 PHE D CD2 1 
ATOM   10733 C CE1 . PHE D 1 355 ? 112.680 131.112 169.291 1.00 112.92 ? 301 PHE D CE1 1 
ATOM   10734 C CE2 . PHE D 1 355 ? 111.662 128.981 168.922 1.00 111.72 ? 301 PHE D CE2 1 
ATOM   10735 C CZ  . PHE D 1 355 ? 111.676 130.203 169.564 1.00 117.47 ? 301 PHE D CZ  1 
ATOM   10736 N N   . VAL D 1 356 ? 116.901 127.448 168.247 1.00 94.30  ? 302 VAL D N   1 
ATOM   10737 C CA  . VAL D 1 356 ? 117.284 126.597 169.370 1.00 95.81  ? 302 VAL D CA  1 
ATOM   10738 C C   . VAL D 1 356 ? 118.472 127.198 170.111 1.00 98.64  ? 302 VAL D C   1 
ATOM   10739 O O   . VAL D 1 356 ? 118.502 127.234 171.345 1.00 108.65 ? 302 VAL D O   1 
ATOM   10740 C CB  . VAL D 1 356 ? 117.584 125.168 168.883 1.00 96.18  ? 302 VAL D CB  1 
ATOM   10741 C CG1 . VAL D 1 356 ? 118.277 124.370 169.973 1.00 97.86  ? 302 VAL D CG1 1 
ATOM   10742 C CG2 . VAL D 1 356 ? 116.301 124.478 168.460 1.00 97.00  ? 302 VAL D CG2 1 
ATOM   10743 N N   . ASN D 1 357 ? 119.470 127.678 169.369 1.00 93.65  ? 303 ASN D N   1 
ATOM   10744 C CA  . ASN D 1 357 ? 120.619 128.325 169.993 1.00 96.42  ? 303 ASN D CA  1 
ATOM   10745 C C   . ASN D 1 357 ? 120.230 129.620 170.691 1.00 100.01 ? 303 ASN D C   1 
ATOM   10746 O O   . ASN D 1 357 ? 120.790 129.937 171.746 1.00 102.30 ? 303 ASN D O   1 
ATOM   10747 C CB  . ASN D 1 357 ? 121.703 128.593 168.947 1.00 97.14  ? 303 ASN D CB  1 
ATOM   10748 C CG  . ASN D 1 357 ? 123.086 128.732 169.558 1.00 99.21  ? 303 ASN D CG  1 
ATOM   10749 O OD1 . ASN D 1 357 ? 123.249 129.291 170.642 1.00 96.25  ? 303 ASN D OD1 1 
ATOM   10750 N ND2 . ASN D 1 357 ? 124.093 128.216 168.862 1.00 101.46 ? 303 ASN D ND2 1 
ATOM   10751 N N   . TYR D 1 358 ? 119.286 130.369 170.127 1.00 100.13 ? 304 TYR D N   1 
ATOM   10752 C CA  . TYR D 1 358 ? 118.767 131.586 170.731 1.00 103.93 ? 304 TYR D CA  1 
ATOM   10753 C C   . TYR D 1 358 ? 118.066 131.342 172.062 1.00 101.78 ? 304 TYR D C   1 
ATOM   10754 O O   . TYR D 1 358 ? 118.220 132.153 172.981 1.00 102.55 ? 304 TYR D O   1 
ATOM   10755 C CB  . TYR D 1 358 ? 117.801 132.270 169.755 1.00 107.44 ? 304 TYR D CB  1 
ATOM   10756 C CG  . TYR D 1 358 ? 117.302 133.629 170.193 1.00 107.84 ? 304 TYR D CG  1 
ATOM   10757 C CD1 . TYR D 1 358 ? 118.027 134.779 169.913 1.00 107.36 ? 304 TYR D CD1 1 
ATOM   10758 C CD2 . TYR D 1 358 ? 116.095 133.764 170.865 1.00 108.28 ? 304 TYR D CD2 1 
ATOM   10759 C CE1 . TYR D 1 358 ? 117.571 136.023 170.304 1.00 111.52 ? 304 TYR D CE1 1 
ATOM   10760 C CE2 . TYR D 1 358 ? 115.631 135.002 171.260 1.00 113.50 ? 304 TYR D CE2 1 
ATOM   10761 C CZ  . TYR D 1 358 ? 116.373 136.129 170.977 1.00 116.83 ? 304 TYR D CZ  1 
ATOM   10762 O OH  . TYR D 1 358 ? 115.914 137.365 171.368 1.00 117.30 ? 304 TYR D OH  1 
ATOM   10763 N N   . ILE D 1 359 ? 117.305 130.255 172.189 1.00 101.15 ? 305 ILE D N   1 
ATOM   10764 C CA  . ILE D 1 359 ? 116.543 130.015 173.413 1.00 103.89 ? 305 ILE D CA  1 
ATOM   10765 C C   . ILE D 1 359 ? 117.083 128.814 174.181 1.00 106.18 ? 305 ILE D C   1 
ATOM   10766 O O   . ILE D 1 359 ? 116.372 128.221 175.001 1.00 110.73 ? 305 ILE D O   1 
ATOM   10767 C CB  . ILE D 1 359 ? 115.046 129.820 173.108 1.00 104.85 ? 305 ILE D CB  1 
ATOM   10768 C CG1 . ILE D 1 359 ? 114.832 128.566 172.260 1.00 102.67 ? 305 ILE D CG1 1 
ATOM   10769 C CG2 . ILE D 1 359 ? 114.477 131.047 172.419 1.00 107.79 ? 305 ILE D CG2 1 
ATOM   10770 C CD1 . ILE D 1 359 ? 113.379 128.238 172.014 1.00 108.26 ? 305 ILE D CD1 1 
ATOM   10771 N N   . PHE D 1 360 ? 118.339 128.449 173.937 1.00 106.52 ? 306 PHE D N   1 
ATOM   10772 C CA  . PHE D 1 360 ? 118.919 127.249 174.526 1.00 111.65 ? 306 PHE D CA  1 
ATOM   10773 C C   . PHE D 1 360 ? 119.441 127.470 175.942 1.00 115.80 ? 306 PHE D C   1 
ATOM   10774 O O   . PHE D 1 360 ? 119.744 126.495 176.638 1.00 113.55 ? 306 PHE D O   1 
ATOM   10775 C CB  . PHE D 1 360 ? 120.027 126.708 173.611 1.00 112.61 ? 306 PHE D CB  1 
ATOM   10776 C CG  . PHE D 1 360 ? 121.407 126.757 174.207 1.00 113.48 ? 306 PHE D CG  1 
ATOM   10777 C CD1 . PHE D 1 360 ? 122.147 127.928 174.190 1.00 114.10 ? 306 PHE D CD1 1 
ATOM   10778 C CD2 . PHE D 1 360 ? 121.977 125.619 174.756 1.00 110.37 ? 306 PHE D CD2 1 
ATOM   10779 C CE1 . PHE D 1 360 ? 123.417 127.969 174.731 1.00 113.80 ? 306 PHE D CE1 1 
ATOM   10780 C CE2 . PHE D 1 360 ? 123.246 125.654 175.298 1.00 109.62 ? 306 PHE D CE2 1 
ATOM   10781 C CZ  . PHE D 1 360 ? 123.968 126.829 175.284 1.00 112.76 ? 306 PHE D CZ  1 
ATOM   10782 N N   . PHE D 1 361 ? 119.524 128.720 176.399 1.00 119.79 ? 307 PHE D N   1 
ATOM   10783 C CA  . PHE D 1 361 ? 119.973 129.009 177.752 1.00 120.67 ? 307 PHE D CA  1 
ATOM   10784 C C   . PHE D 1 361 ? 118.841 129.335 178.716 1.00 118.18 ? 307 PHE D C   1 
ATOM   10785 O O   . PHE D 1 361 ? 119.096 129.455 179.920 1.00 116.08 ? 307 PHE D O   1 
ATOM   10786 C CB  . PHE D 1 361 ? 120.979 130.172 177.750 1.00 120.90 ? 307 PHE D CB  1 
ATOM   10787 C CG  . PHE D 1 361 ? 121.977 130.112 178.873 1.00 123.30 ? 307 PHE D CG  1 
ATOM   10788 C CD1 . PHE D 1 361 ? 123.063 129.255 178.803 1.00 120.82 ? 307 PHE D CD1 1 
ATOM   10789 C CD2 . PHE D 1 361 ? 121.834 130.912 179.995 1.00 124.50 ? 307 PHE D CD2 1 
ATOM   10790 C CE1 . PHE D 1 361 ? 123.985 129.193 179.831 1.00 121.22 ? 307 PHE D CE1 1 
ATOM   10791 C CE2 . PHE D 1 361 ? 122.754 130.855 181.027 1.00 123.95 ? 307 PHE D CE2 1 
ATOM   10792 C CZ  . PHE D 1 361 ? 123.830 129.995 180.944 1.00 122.77 ? 307 PHE D CZ  1 
ATOM   10793 N N   . SER D 1 362 ? 117.607 129.473 178.233 1.00 118.45 ? 308 SER D N   1 
ATOM   10794 C CA  . SER D 1 362 ? 116.463 129.761 179.108 1.00 118.22 ? 308 SER D CA  1 
ATOM   10795 C C   . SER D 1 362 ? 115.699 128.475 179.411 1.00 120.65 ? 308 SER D C   1 
ATOM   10796 O O   . SER D 1 362 ? 115.452 128.147 180.575 1.00 121.88 ? 308 SER D O   1 
ATOM   10797 C CB  . SER D 1 362 ? 115.553 130.809 178.466 1.00 109.84 ? 308 SER D CB  1 
ATOM   10798 O OG  . SER D 1 362 ? 114.946 130.299 177.293 1.00 107.31 ? 308 SER D OG  1 
ATOM   10799 N N   . GLN D 1 363 ? 115.318 127.742 178.367 1.00 119.35 ? 309 GLN D N   1 
ATOM   10800 C CA  . GLN D 1 363 ? 114.598 126.477 178.505 1.00 119.61 ? 309 GLN D CA  1 
ATOM   10801 C C   . GLN D 1 363 ? 115.308 125.410 177.684 1.00 118.54 ? 309 GLN D C   1 
ATOM   10802 O O   . GLN D 1 363 ? 114.912 125.121 176.546 1.00 116.48 ? 309 GLN D O   1 
ATOM   10803 C CB  . GLN D 1 363 ? 113.141 126.614 178.071 1.00 121.32 ? 309 GLN D CB  1 
ATOM   10804 C CG  . GLN D 1 363 ? 112.329 127.594 178.893 1.00 120.11 ? 309 GLN D CG  1 
ATOM   10805 C CD  . GLN D 1 363 ? 110.851 127.524 178.575 1.00 121.69 ? 309 GLN D CD  1 
ATOM   10806 O OE1 . GLN D 1 363 ? 110.344 126.484 178.152 1.00 114.18 ? 309 GLN D OE1 1 
ATOM   10807 N NE2 . GLN D 1 363 ? 110.149 128.633 178.771 1.00 127.79 ? 309 GLN D NE2 1 
ATOM   10808 N N   . PRO D 1 364 ? 116.370 124.810 178.224 1.00 118.70 ? 310 PRO D N   1 
ATOM   10809 C CA  . PRO D 1 364 ? 117.002 123.677 177.527 1.00 117.98 ? 310 PRO D CA  1 
ATOM   10810 C C   . PRO D 1 364 ? 116.065 122.501 177.329 1.00 114.53 ? 310 PRO D C   1 
ATOM   10811 O O   . PRO D 1 364 ? 116.213 121.765 176.344 1.00 112.62 ? 310 PRO D O   1 
ATOM   10812 C CB  . PRO D 1 364 ? 118.178 123.313 178.444 1.00 117.73 ? 310 PRO D CB  1 
ATOM   10813 C CG  . PRO D 1 364 ? 117.792 123.846 179.787 1.00 117.49 ? 310 PRO D CG  1 
ATOM   10814 C CD  . PRO D 1 364 ? 117.018 125.100 179.513 1.00 116.82 ? 310 PRO D CD  1 
ATOM   10815 N N   . ALA D 1 365 ? 115.103 122.302 178.234 1.00 111.84 ? 311 ALA D N   1 
ATOM   10816 C CA  . ALA D 1 365 ? 114.126 121.234 178.057 1.00 109.86 ? 311 ALA D CA  1 
ATOM   10817 C C   . ALA D 1 365 ? 113.269 121.472 176.822 1.00 113.02 ? 311 ALA D C   1 
ATOM   10818 O O   . ALA D 1 365 ? 112.873 120.518 176.141 1.00 116.18 ? 311 ALA D O   1 
ATOM   10819 C CB  . ALA D 1 365 ? 113.251 121.111 179.304 1.00 108.29 ? 311 ALA D CB  1 
ATOM   10820 N N   . ARG D 1 366 ? 112.966 122.735 176.516 1.00 112.03 ? 312 ARG D N   1 
ATOM   10821 C CA  . ARG D 1 366 ? 112.205 123.030 175.307 1.00 111.71 ? 312 ARG D CA  1 
ATOM   10822 C C   . ARG D 1 366 ? 113.068 122.867 174.062 1.00 111.78 ? 312 ARG D C   1 
ATOM   10823 O O   . ARG D 1 366 ? 112.591 122.405 173.021 1.00 113.46 ? 312 ARG D O   1 
ATOM   10824 C CB  . ARG D 1 366 ? 111.622 124.440 175.374 1.00 113.10 ? 312 ARG D CB  1 
ATOM   10825 C CG  . ARG D 1 366 ? 110.810 124.798 174.142 1.00 113.98 ? 312 ARG D CG  1 
ATOM   10826 C CD  . ARG D 1 366 ? 110.289 126.218 174.192 1.00 120.85 ? 312 ARG D CD  1 
ATOM   10827 N NE  . ARG D 1 366 ? 109.707 126.611 172.915 1.00 120.33 ? 312 ARG D NE  1 
ATOM   10828 C CZ  . ARG D 1 366 ? 109.105 127.770 172.690 1.00 120.97 ? 312 ARG D CZ  1 
ATOM   10829 N NH1 . ARG D 1 366 ? 108.970 128.675 173.646 1.00 121.41 ? 312 ARG D NH1 1 
ATOM   10830 N NH2 . ARG D 1 366 ? 108.627 128.028 171.477 1.00 116.40 ? 312 ARG D NH2 1 
ATOM   10831 N N   . ALA D 1 367 ? 114.343 123.255 174.146 1.00 113.29 ? 313 ALA D N   1 
ATOM   10832 C CA  . ALA D 1 367 ? 115.239 123.102 173.004 1.00 114.52 ? 313 ALA D CA  1 
ATOM   10833 C C   . ALA D 1 367 ? 115.428 121.633 172.645 1.00 110.85 ? 313 ALA D C   1 
ATOM   10834 O O   . ALA D 1 367 ? 115.416 121.262 171.462 1.00 108.62 ? 313 ALA D O   1 
ATOM   10835 C CB  . ALA D 1 367 ? 116.586 123.761 173.301 1.00 113.01 ? 313 ALA D CB  1 
ATOM   10836 N N   . ALA D 1 368 ? 115.606 120.781 173.657 1.00 107.89 ? 314 ALA D N   1 
ATOM   10837 C CA  . ALA D 1 368 ? 115.706 119.350 173.408 1.00 108.52 ? 314 ALA D CA  1 
ATOM   10838 C C   . ALA D 1 368 ? 114.441 118.799 172.768 1.00 107.26 ? 314 ALA D C   1 
ATOM   10839 O O   . ALA D 1 368 ? 114.532 117.969 171.858 1.00 106.41 ? 314 ALA D O   1 
ATOM   10840 C CB  . ALA D 1 368 ? 116.004 118.606 174.709 1.00 109.44 ? 314 ALA D CB  1 
ATOM   10841 N N   . ALA D 1 369 ? 113.269 119.248 173.215 1.00 106.17 ? 422 ALA D N   1 
ATOM   10842 C CA  . ALA D 1 369 ? 112.007 118.847 172.608 1.00 106.12 ? 422 ALA D CA  1 
ATOM   10843 C C   . ALA D 1 369 ? 111.895 119.301 171.159 1.00 106.64 ? 422 ALA D C   1 
ATOM   10844 O O   . ALA D 1 369 ? 111.404 118.548 170.311 1.00 106.13 ? 422 ALA D O   1 
ATOM   10845 C CB  . ALA D 1 369 ? 110.834 119.401 173.419 1.00 104.66 ? 422 ALA D CB  1 
ATOM   10846 N N   . ILE D 1 370 ? 112.338 120.521 170.865 1.00 104.99 ? 423 ILE D N   1 
ATOM   10847 C CA  . ILE D 1 370 ? 112.308 121.055 169.508 1.00 97.98  ? 423 ILE D CA  1 
ATOM   10848 C C   . ILE D 1 370 ? 113.174 120.182 168.614 1.00 99.09  ? 423 ILE D C   1 
ATOM   10849 O O   . ILE D 1 370 ? 112.762 119.806 167.511 1.00 102.95 ? 423 ILE D O   1 
ATOM   10850 C CB  . ILE D 1 370 ? 112.769 122.523 169.468 1.00 94.90  ? 423 ILE D CB  1 
ATOM   10851 C CG1 . ILE D 1 370 ? 111.742 123.424 170.156 1.00 104.89 ? 423 ILE D CG1 1 
ATOM   10852 C CG2 . ILE D 1 370 ? 112.981 122.973 168.034 1.00 93.82  ? 423 ILE D CG2 1 
ATOM   10853 C CD1 . ILE D 1 370 ? 112.093 124.896 170.117 1.00 105.46 ? 423 ILE D CD1 1 
ATOM   10854 N N   . ASP D 1 371 ? 114.373 119.840 169.084 1.00 99.04  ? 424 ASP D N   1 
ATOM   10855 C CA  . ASP D 1 371 ? 115.249 118.949 168.327 1.00 98.53  ? 424 ASP D CA  1 
ATOM   10856 C C   . ASP D 1 371 ? 114.656 117.560 168.125 1.00 95.33  ? 424 ASP D C   1 
ATOM   10857 O O   . ASP D 1 371 ? 114.718 117.020 167.012 1.00 95.09  ? 424 ASP D O   1 
ATOM   10858 C CB  . ASP D 1 371 ? 116.612 118.826 169.013 1.00 103.34 ? 424 ASP D CB  1 
ATOM   10859 C CG  . ASP D 1 371 ? 117.531 119.985 168.689 1.00 101.23 ? 424 ASP D CG  1 
ATOM   10860 O OD1 . ASP D 1 371 ? 117.045 120.991 168.133 1.00 98.57  ? 424 ASP D OD1 1 
ATOM   10861 O OD2 . ASP D 1 371 ? 118.741 119.886 168.979 1.00 102.12 ? 424 ASP D OD2 1 
ATOM   10862 N N   . ARG D 1 372 ? 114.069 116.974 169.173 1.00 96.38  ? 425 ARG D N   1 
ATOM   10863 C CA  . ARG D 1 372 ? 113.449 115.660 169.035 1.00 96.86  ? 425 ARG D CA  1 
ATOM   10864 C C   . ARG D 1 372 ? 112.321 115.691 168.016 1.00 94.76  ? 425 ARG D C   1 
ATOM   10865 O O   . ARG D 1 372 ? 112.183 114.772 167.200 1.00 98.58  ? 425 ARG D O   1 
ATOM   10866 C CB  . ARG D 1 372 ? 112.922 115.171 170.384 1.00 102.44 ? 425 ARG D CB  1 
ATOM   10867 C CG  . ARG D 1 372 ? 113.984 114.938 171.440 1.00 104.26 ? 425 ARG D CG  1 
ATOM   10868 C CD  . ARG D 1 372 ? 113.404 114.198 172.634 1.00 106.94 ? 425 ARG D CD  1 
ATOM   10869 N NE  . ARG D 1 372 ? 112.122 114.750 173.057 1.00 106.83 ? 425 ARG D NE  1 
ATOM   10870 C CZ  . ARG D 1 372 ? 111.975 115.674 173.997 1.00 107.81 ? 425 ARG D CZ  1 
ATOM   10871 N NH1 . ARG D 1 372 ? 113.017 116.180 174.637 1.00 108.51 ? 425 ARG D NH1 1 
ATOM   10872 N NH2 . ARG D 1 372 ? 110.753 116.101 174.302 1.00 102.59 ? 425 ARG D NH2 1 
ATOM   10873 N N   . TRP D 1 373 ? 111.502 116.743 168.047 1.00 89.10  ? 426 TRP D N   1 
ATOM   10874 C CA  . TRP D 1 373 ? 110.409 116.848 167.090 1.00 93.29  ? 426 TRP D CA  1 
ATOM   10875 C C   . TRP D 1 373 ? 110.905 117.237 165.705 1.00 92.77  ? 426 TRP D C   1 
ATOM   10876 O O   . TRP D 1 373 ? 110.294 116.849 164.705 1.00 90.89  ? 426 TRP D O   1 
ATOM   10877 C CB  . TRP D 1 373 ? 109.370 117.852 167.584 1.00 98.02  ? 426 TRP D CB  1 
ATOM   10878 C CG  . TRP D 1 373 ? 108.428 117.275 168.587 1.00 107.99 ? 426 TRP D CG  1 
ATOM   10879 C CD1 . TRP D 1 373 ? 108.645 117.125 169.924 1.00 110.52 ? 426 TRP D CD1 1 
ATOM   10880 C CD2 . TRP D 1 373 ? 107.113 116.769 168.334 1.00 110.55 ? 426 TRP D CD2 1 
ATOM   10881 N NE1 . TRP D 1 373 ? 107.547 116.556 170.521 1.00 107.12 ? 426 TRP D NE1 1 
ATOM   10882 C CE2 . TRP D 1 373 ? 106.592 116.328 169.566 1.00 109.88 ? 426 TRP D CE2 1 
ATOM   10883 C CE3 . TRP D 1 373 ? 106.326 116.646 167.186 1.00 109.59 ? 426 TRP D CE3 1 
ATOM   10884 C CZ2 . TRP D 1 373 ? 105.319 115.773 169.682 1.00 111.57 ? 426 TRP D CZ2 1 
ATOM   10885 C CZ3 . TRP D 1 373 ? 105.064 116.096 167.302 1.00 112.63 ? 426 TRP D CZ3 1 
ATOM   10886 C CH2 . TRP D 1 373 ? 104.573 115.667 168.541 1.00 111.33 ? 426 TRP D CH2 1 
ATOM   10887 N N   . SER D 1 374 ? 111.992 118.007 165.622 1.00 91.52  ? 427 SER D N   1 
ATOM   10888 C CA  . SER D 1 374 ? 112.555 118.342 164.318 1.00 86.52  ? 427 SER D CA  1 
ATOM   10889 C C   . SER D 1 374 ? 113.050 117.095 163.600 1.00 84.67  ? 427 SER D C   1 
ATOM   10890 O O   . SER D 1 374 ? 112.790 116.912 162.401 1.00 83.00  ? 427 SER D O   1 
ATOM   10891 C CB  . SER D 1 374 ? 113.689 119.353 164.474 1.00 84.17  ? 427 SER D CB  1 
ATOM   10892 O OG  . SER D 1 374 ? 113.226 120.557 165.058 1.00 91.70  ? 427 SER D OG  1 
ATOM   10893 N N   . ARG D 1 375 ? 113.742 116.212 164.329 1.00 85.56  ? 428 ARG D N   1 
ATOM   10894 C CA  . ARG D 1 375 ? 114.294 115.001 163.726 1.00 79.07  ? 428 ARG D CA  1 
ATOM   10895 C C   . ARG D 1 375 ? 113.222 114.117 163.108 1.00 80.58  ? 428 ARG D C   1 
ATOM   10896 O O   . ARG D 1 375 ? 113.539 113.283 162.255 1.00 82.59  ? 428 ARG D O   1 
ATOM   10897 C CB  . ARG D 1 375 ? 115.065 114.186 164.763 1.00 80.24  ? 428 ARG D CB  1 
ATOM   10898 C CG  . ARG D 1 375 ? 116.273 114.874 165.357 1.00 85.45  ? 428 ARG D CG  1 
ATOM   10899 C CD  . ARG D 1 375 ? 116.821 114.040 166.497 1.00 86.35  ? 428 ARG D CD  1 
ATOM   10900 N NE  . ARG D 1 375 ? 117.642 114.817 167.416 1.00 93.68  ? 428 ARG D NE  1 
ATOM   10901 C CZ  . ARG D 1 375 ? 117.980 114.412 168.631 1.00 98.03  ? 428 ARG D CZ  1 
ATOM   10902 N NH1 . ARG D 1 375 ? 117.575 113.247 169.107 1.00 99.26  ? 428 ARG D NH1 1 
ATOM   10903 N NH2 . ARG D 1 375 ? 118.736 115.199 169.391 1.00 101.95 ? 428 ARG D NH2 1 
ATOM   10904 N N   . ILE D 1 376 ? 111.970 114.269 163.527 1.00 83.02  ? 429 ILE D N   1 
ATOM   10905 C CA  . ILE D 1 376 ? 110.865 113.507 162.965 1.00 84.36  ? 429 ILE D CA  1 
ATOM   10906 C C   . ILE D 1 376 ? 110.115 114.305 161.907 1.00 87.25  ? 429 ILE D C   1 
ATOM   10907 O O   . ILE D 1 376 ? 109.726 113.758 160.875 1.00 90.95  ? 429 ILE D O   1 
ATOM   10908 C CB  . ILE D 1 376 ? 109.914 113.044 164.089 1.00 84.48  ? 429 ILE D CB  1 
ATOM   10909 C CG1 . ILE D 1 376 ? 110.678 112.228 165.134 1.00 89.95  ? 429 ILE D CG1 1 
ATOM   10910 C CG2 . ILE D 1 376 ? 108.766 112.232 163.517 1.00 79.50  ? 429 ILE D CG2 1 
ATOM   10911 C CD1 . ILE D 1 376 ? 109.817 111.740 166.280 1.00 91.36  ? 429 ILE D CD1 1 
ATOM   10912 N N   . VAL D 1 377 ? 109.913 115.603 162.141 1.00 85.05  ? 430 VAL D N   1 
ATOM   10913 C CA  . VAL D 1 377 ? 109.103 116.408 161.232 1.00 82.81  ? 430 VAL D CA  1 
ATOM   10914 C C   . VAL D 1 377 ? 109.822 116.615 159.905 1.00 84.23  ? 430 VAL D C   1 
ATOM   10915 O O   . VAL D 1 377 ? 109.225 116.462 158.833 1.00 80.87  ? 430 VAL D O   1 
ATOM   10916 C CB  . VAL D 1 377 ? 108.732 117.750 161.890 1.00 82.28  ? 430 VAL D CB  1 
ATOM   10917 C CG1 . VAL D 1 377 ? 108.191 118.719 160.852 1.00 78.37  ? 430 VAL D CG1 1 
ATOM   10918 C CG2 . VAL D 1 377 ? 107.707 117.528 162.987 1.00 91.97  ? 430 VAL D CG2 1 
ATOM   10919 N N   . PHE D 1 378 ? 111.108 116.971 159.949 1.00 83.38  ? 431 PHE D N   1 
ATOM   10920 C CA  . PHE D 1 378 ? 111.804 117.313 158.709 1.00 79.77  ? 431 PHE D CA  1 
ATOM   10921 C C   . PHE D 1 378 ? 111.874 116.159 157.715 1.00 76.85  ? 431 PHE D C   1 
ATOM   10922 O O   . PHE D 1 378 ? 111.521 116.368 156.539 1.00 71.78  ? 431 PHE D O   1 
ATOM   10923 C CB  . PHE D 1 378 ? 113.195 117.866 159.033 1.00 76.73  ? 431 PHE D CB  1 
ATOM   10924 C CG  . PHE D 1 378 ? 113.209 119.338 159.302 1.00 74.55  ? 431 PHE D CG  1 
ATOM   10925 C CD1 . PHE D 1 378 ? 112.743 119.839 160.504 1.00 76.18  ? 431 PHE D CD1 1 
ATOM   10926 C CD2 . PHE D 1 378 ? 113.693 120.222 158.355 1.00 75.38  ? 431 PHE D CD2 1 
ATOM   10927 C CE1 . PHE D 1 378 ? 112.755 121.195 160.755 1.00 81.86  ? 431 PHE D CE1 1 
ATOM   10928 C CE2 . PHE D 1 378 ? 113.709 121.578 158.599 1.00 74.27  ? 431 PHE D CE2 1 
ATOM   10929 C CZ  . PHE D 1 378 ? 113.240 122.066 159.801 1.00 76.35  ? 431 PHE D CZ  1 
ATOM   10930 N N   . PRO D 1 379 ? 112.312 114.947 158.083 1.00 74.26  ? 432 PRO D N   1 
ATOM   10931 C CA  . PRO D 1 379 ? 112.301 113.860 157.090 1.00 74.49  ? 432 PRO D CA  1 
ATOM   10932 C C   . PRO D 1 379 ? 110.911 113.527 156.585 1.00 78.83  ? 432 PRO D C   1 
ATOM   10933 O O   . PRO D 1 379 ? 110.733 113.284 155.385 1.00 85.59  ? 432 PRO D O   1 
ATOM   10934 C CB  . PRO D 1 379 ? 112.926 112.682 157.852 1.00 72.09  ? 432 PRO D CB  1 
ATOM   10935 C CG  . PRO D 1 379 ? 113.707 113.308 158.945 1.00 76.09  ? 432 PRO D CG  1 
ATOM   10936 C CD  . PRO D 1 379 ? 112.911 114.503 159.354 1.00 74.60  ? 432 PRO D CD  1 
ATOM   10937 N N   . PHE D 1 380 ? 109.912 113.520 157.470 1.00 73.42  ? 433 PHE D N   1 
ATOM   10938 C CA  . PHE D 1 380 ? 108.553 113.205 157.045 1.00 74.73  ? 433 PHE D CA  1 
ATOM   10939 C C   . PHE D 1 380 ? 108.010 114.267 156.097 1.00 80.43  ? 433 PHE D C   1 
ATOM   10940 O O   . PHE D 1 380 ? 107.372 113.942 155.087 1.00 86.60  ? 433 PHE D O   1 
ATOM   10941 C CB  . PHE D 1 380 ? 107.648 113.059 158.267 1.00 74.37  ? 433 PHE D CB  1 
ATOM   10942 C CG  . PHE D 1 380 ? 106.270 112.567 157.944 1.00 74.48  ? 433 PHE D CG  1 
ATOM   10943 C CD1 . PHE D 1 380 ? 106.032 111.218 157.755 1.00 77.82  ? 433 PHE D CD1 1 
ATOM   10944 C CD2 . PHE D 1 380 ? 105.212 113.452 157.836 1.00 74.28  ? 433 PHE D CD2 1 
ATOM   10945 C CE1 . PHE D 1 380 ? 104.765 110.759 157.460 1.00 85.26  ? 433 PHE D CE1 1 
ATOM   10946 C CE2 . PHE D 1 380 ? 103.942 113.000 157.541 1.00 79.77  ? 433 PHE D CE2 1 
ATOM   10947 C CZ  . PHE D 1 380 ? 103.718 111.651 157.354 1.00 90.19  ? 433 PHE D CZ  1 
ATOM   10948 N N   . THR D 1 381 ? 108.261 115.542 156.402 1.00 74.41  ? 434 THR D N   1 
ATOM   10949 C CA  . THR D 1 381 ? 107.801 116.614 155.527 1.00 74.26  ? 434 THR D CA  1 
ATOM   10950 C C   . THR D 1 381 ? 108.496 116.556 154.173 1.00 75.78  ? 434 THR D C   1 
ATOM   10951 O O   . THR D 1 381 ? 107.861 116.770 153.134 1.00 73.32  ? 434 THR D O   1 
ATOM   10952 C CB  . THR D 1 381 ? 108.033 117.970 156.189 1.00 76.35  ? 434 THR D CB  1 
ATOM   10953 O OG1 . THR D 1 381 ? 107.778 117.865 157.594 1.00 81.59  ? 434 THR D OG1 1 
ATOM   10954 C CG2 . THR D 1 381 ? 107.103 119.012 155.593 1.00 77.22  ? 434 THR D CG2 1 
ATOM   10955 N N   . PHE D 1 382 ? 109.800 116.270 154.165 1.00 77.67  ? 435 PHE D N   1 
ATOM   10956 C CA  . PHE D 1 382 ? 110.518 116.144 152.900 1.00 76.24  ? 435 PHE D CA  1 
ATOM   10957 C C   . PHE D 1 382 ? 109.993 114.972 152.081 1.00 73.93  ? 435 PHE D C   1 
ATOM   10958 O O   . PHE D 1 382 ? 109.863 115.070 150.856 1.00 75.57  ? 435 PHE D O   1 
ATOM   10959 C CB  . PHE D 1 382 ? 112.013 115.991 153.166 1.00 77.74  ? 435 PHE D CB  1 
ATOM   10960 C CG  . PHE D 1 382 ? 112.850 115.915 151.923 1.00 76.55  ? 435 PHE D CG  1 
ATOM   10961 C CD1 . PHE D 1 382 ? 113.142 117.057 151.199 1.00 74.30  ? 435 PHE D CD1 1 
ATOM   10962 C CD2 . PHE D 1 382 ? 113.360 114.704 151.488 1.00 74.61  ? 435 PHE D CD2 1 
ATOM   10963 C CE1 . PHE D 1 382 ? 113.917 116.991 150.059 1.00 73.44  ? 435 PHE D CE1 1 
ATOM   10964 C CE2 . PHE D 1 382 ? 114.138 114.632 150.350 1.00 74.15  ? 435 PHE D CE2 1 
ATOM   10965 C CZ  . PHE D 1 382 ? 114.415 115.778 149.635 1.00 71.33  ? 435 PHE D CZ  1 
ATOM   10966 N N   . SER D 1 383 ? 109.692 113.851 152.740 1.00 71.04  ? 436 SER D N   1 
ATOM   10967 C CA  . SER D 1 383 ? 109.139 112.701 152.033 1.00 68.26  ? 436 SER D CA  1 
ATOM   10968 C C   . SER D 1 383 ? 107.771 113.019 151.445 1.00 70.57  ? 436 SER D C   1 
ATOM   10969 O O   . SER D 1 383 ? 107.470 112.627 150.312 1.00 79.33  ? 436 SER D O   1 
ATOM   10970 C CB  . SER D 1 383 ? 109.052 111.499 152.972 1.00 74.70  ? 436 SER D CB  1 
ATOM   10971 O OG  . SER D 1 383 ? 110.334 111.131 153.449 1.00 78.93  ? 436 SER D OG  1 
ATOM   10972 N N   . LEU D 1 384 ? 106.927 113.724 152.201 1.00 66.81  ? 437 LEU D N   1 
ATOM   10973 C CA  . LEU D 1 384 ? 105.622 114.122 151.681 1.00 70.41  ? 437 LEU D CA  1 
ATOM   10974 C C   . LEU D 1 384 ? 105.767 115.068 150.494 1.00 75.63  ? 437 LEU D C   1 
ATOM   10975 O O   . LEU D 1 384 ? 105.027 114.961 149.505 1.00 76.82  ? 437 LEU D O   1 
ATOM   10976 C CB  . LEU D 1 384 ? 104.797 114.772 152.791 1.00 72.15  ? 437 LEU D CB  1 
ATOM   10977 C CG  . LEU D 1 384 ? 103.344 115.120 152.471 1.00 74.60  ? 437 LEU D CG  1 
ATOM   10978 C CD1 . LEU D 1 384 ? 102.508 113.857 152.346 1.00 68.97  ? 437 LEU D CD1 1 
ATOM   10979 C CD2 . LEU D 1 384 ? 102.770 116.047 153.530 1.00 72.14  ? 437 LEU D CD2 1 
ATOM   10980 N N   . PHE D 1 385 ? 106.712 116.007 150.581 1.00 74.24  ? 438 PHE D N   1 
ATOM   10981 C CA  . PHE D 1 385 ? 106.965 116.920 149.472 1.00 72.36  ? 438 PHE D CA  1 
ATOM   10982 C C   . PHE D 1 385 ? 107.425 116.166 148.232 1.00 74.25  ? 438 PHE D C   1 
ATOM   10983 O O   . PHE D 1 385 ? 106.979 116.460 147.118 1.00 74.86  ? 438 PHE D O   1 
ATOM   10984 C CB  . PHE D 1 385 ? 108.001 117.965 149.885 1.00 74.74  ? 438 PHE D CB  1 
ATOM   10985 C CG  . PHE D 1 385 ? 108.662 118.658 148.728 1.00 73.78  ? 438 PHE D CG  1 
ATOM   10986 C CD1 . PHE D 1 385 ? 107.977 119.603 147.985 1.00 70.96  ? 438 PHE D CD1 1 
ATOM   10987 C CD2 . PHE D 1 385 ? 109.976 118.373 148.394 1.00 71.60  ? 438 PHE D CD2 1 
ATOM   10988 C CE1 . PHE D 1 385 ? 108.586 120.243 146.924 1.00 69.36  ? 438 PHE D CE1 1 
ATOM   10989 C CE2 . PHE D 1 385 ? 110.589 119.010 147.335 1.00 71.07  ? 438 PHE D CE2 1 
ATOM   10990 C CZ  . PHE D 1 385 ? 109.894 119.946 146.600 1.00 71.50  ? 438 PHE D CZ  1 
ATOM   10991 N N   . ASN D 1 386 ? 108.318 115.191 148.405 1.00 74.40  ? 439 ASN D N   1 
ATOM   10992 C CA  . ASN D 1 386 ? 108.754 114.385 147.269 1.00 67.34  ? 439 ASN D CA  1 
ATOM   10993 C C   . ASN D 1 386 ? 107.596 113.595 146.680 1.00 69.60  ? 439 ASN D C   1 
ATOM   10994 O O   . ASN D 1 386 ? 107.468 113.489 145.455 1.00 73.81  ? 439 ASN D O   1 
ATOM   10995 C CB  . ASN D 1 386 ? 109.882 113.446 147.689 1.00 68.66  ? 439 ASN D CB  1 
ATOM   10996 C CG  . ASN D 1 386 ? 111.199 114.165 147.855 1.00 75.65  ? 439 ASN D CG  1 
ATOM   10997 O OD1 . ASN D 1 386 ? 112.092 114.048 147.018 1.00 72.10  ? 439 ASN D OD1 1 
ATOM   10998 N ND2 . ASN D 1 386 ? 111.323 114.925 148.935 1.00 80.00  ? 439 ASN D ND2 1 
ATOM   10999 N N   . LEU D 1 387 ? 106.744 113.029 147.536 1.00 70.92  ? 440 LEU D N   1 
ATOM   11000 C CA  . LEU D 1 387 ? 105.588 112.283 147.051 1.00 72.24  ? 440 LEU D CA  1 
ATOM   11001 C C   . LEU D 1 387 ? 104.690 113.162 146.189 1.00 74.49  ? 440 LEU D C   1 
ATOM   11002 O O   . LEU D 1 387 ? 104.336 112.792 145.063 1.00 77.90  ? 440 LEU D O   1 
ATOM   11003 C CB  . LEU D 1 387 ? 104.804 111.710 148.232 1.00 73.56  ? 440 LEU D CB  1 
ATOM   11004 C CG  . LEU D 1 387 ? 103.409 111.164 147.921 1.00 76.32  ? 440 LEU D CG  1 
ATOM   11005 C CD1 . LEU D 1 387 ? 103.497 109.959 147.000 1.00 72.21  ? 440 LEU D CD1 1 
ATOM   11006 C CD2 . LEU D 1 387 ? 102.671 110.812 149.202 1.00 78.52  ? 440 LEU D CD2 1 
ATOM   11007 N N   . VAL D 1 388 ? 104.327 114.342 146.696 1.00 72.14  ? 441 VAL D N   1 
ATOM   11008 C CA  . VAL D 1 388 ? 103.407 115.196 145.950 1.00 76.12  ? 441 VAL D CA  1 
ATOM   11009 C C   . VAL D 1 388 ? 104.070 115.721 144.679 1.00 74.56  ? 441 VAL D C   1 
ATOM   11010 O O   . VAL D 1 388 ? 103.433 115.805 143.621 1.00 71.10  ? 441 VAL D O   1 
ATOM   11011 C CB  . VAL D 1 388 ? 102.867 116.332 146.840 1.00 77.57  ? 441 VAL D CB  1 
ATOM   11012 C CG1 . VAL D 1 388 ? 103.987 117.203 147.369 1.00 74.97  ? 441 VAL D CG1 1 
ATOM   11013 C CG2 . VAL D 1 388 ? 101.855 117.169 146.073 1.00 80.65  ? 441 VAL D CG2 1 
ATOM   11014 N N   . TYR D 1 389 ? 105.361 116.061 144.750 1.00 73.51  ? 442 TYR D N   1 
ATOM   11015 C CA  . TYR D 1 389 ? 106.067 116.539 143.567 1.00 68.24  ? 442 TYR D CA  1 
ATOM   11016 C C   . TYR D 1 389 ? 106.094 115.476 142.478 1.00 65.90  ? 442 TYR D C   1 
ATOM   11017 O O   . TYR D 1 389 ? 105.718 115.737 141.330 1.00 68.04  ? 442 TYR D O   1 
ATOM   11018 C CB  . TYR D 1 389 ? 107.487 116.961 143.947 1.00 65.89  ? 442 TYR D CB  1 
ATOM   11019 C CG  . TYR D 1 389 ? 108.383 117.266 142.769 1.00 63.09  ? 442 TYR D CG  1 
ATOM   11020 C CD1 . TYR D 1 389 ? 109.196 116.286 142.219 1.00 67.41  ? 442 TYR D CD1 1 
ATOM   11021 C CD2 . TYR D 1 389 ? 108.423 118.535 142.213 1.00 61.57  ? 442 TYR D CD2 1 
ATOM   11022 C CE1 . TYR D 1 389 ? 110.016 116.558 141.147 1.00 68.50  ? 442 TYR D CE1 1 
ATOM   11023 C CE2 . TYR D 1 389 ? 109.243 118.816 141.140 1.00 65.90  ? 442 TYR D CE2 1 
ATOM   11024 C CZ  . TYR D 1 389 ? 110.037 117.824 140.611 1.00 65.73  ? 442 TYR D CZ  1 
ATOM   11025 O OH  . TYR D 1 389 ? 110.857 118.097 139.542 1.00 63.96  ? 442 TYR D OH  1 
ATOM   11026 N N   . TRP D 1 390 ? 106.530 114.263 142.822 1.00 65.56  ? 443 TRP D N   1 
ATOM   11027 C CA  . TRP D 1 390 ? 106.644 113.212 141.822 1.00 67.56  ? 443 TRP D CA  1 
ATOM   11028 C C   . TRP D 1 390 ? 105.290 112.709 141.342 1.00 71.77  ? 443 TRP D C   1 
ATOM   11029 O O   . TRP D 1 390 ? 105.208 112.168 140.236 1.00 73.66  ? 443 TRP D O   1 
ATOM   11030 C CB  . TRP D 1 390 ? 107.478 112.054 142.368 1.00 67.27  ? 443 TRP D CB  1 
ATOM   11031 C CG  . TRP D 1 390 ? 108.938 112.376 142.462 1.00 69.33  ? 443 TRP D CG  1 
ATOM   11032 C CD1 . TRP D 1 390 ? 109.671 112.536 143.600 1.00 74.16  ? 443 TRP D CD1 1 
ATOM   11033 C CD2 . TRP D 1 390 ? 109.840 112.589 141.371 1.00 67.50  ? 443 TRP D CD2 1 
ATOM   11034 N NE1 . TRP D 1 390 ? 110.976 112.830 143.285 1.00 71.46  ? 443 TRP D NE1 1 
ATOM   11035 C CE2 . TRP D 1 390 ? 111.105 112.867 141.923 1.00 66.89  ? 443 TRP D CE2 1 
ATOM   11036 C CE3 . TRP D 1 390 ? 109.700 112.567 139.980 1.00 67.81  ? 443 TRP D CE3 1 
ATOM   11037 C CZ2 . TRP D 1 390 ? 112.223 113.122 141.133 1.00 62.03  ? 443 TRP D CZ2 1 
ATOM   11038 C CZ3 . TRP D 1 390 ? 110.811 112.821 139.198 1.00 67.58  ? 443 TRP D CZ3 1 
ATOM   11039 C CH2 . TRP D 1 390 ? 112.056 113.095 139.777 1.00 66.03  ? 443 TRP D CH2 1 
ATOM   11040 N N   . LEU D 1 391 ? 104.228 112.863 142.137 1.00 69.44  ? 444 LEU D N   1 
ATOM   11041 C CA  . LEU D 1 391 ? 102.905 112.528 141.621 1.00 70.65  ? 444 LEU D CA  1 
ATOM   11042 C C   . LEU D 1 391 ? 102.358 113.609 140.700 1.00 72.48  ? 444 LEU D C   1 
ATOM   11043 O O   . LEU D 1 391 ? 101.611 113.296 139.766 1.00 74.95  ? 444 LEU D O   1 
ATOM   11044 C CB  . LEU D 1 391 ? 101.926 112.275 142.768 1.00 75.52  ? 444 LEU D CB  1 
ATOM   11045 C CG  . LEU D 1 391 ? 101.781 110.819 143.215 1.00 79.08  ? 444 LEU D CG  1 
ATOM   11046 C CD1 . LEU D 1 391 ? 100.548 110.646 144.088 1.00 80.75  ? 444 LEU D CD1 1 
ATOM   11047 C CD2 . LEU D 1 391 ? 101.723 109.887 142.014 1.00 78.29  ? 444 LEU D CD2 1 
ATOM   11048 N N   . TYR D 1 392 ? 102.709 114.875 140.938 1.00 71.95  ? 445 TYR D N   1 
ATOM   11049 C CA  . TYR D 1 392 ? 102.184 115.948 140.097 1.00 69.92  ? 445 TYR D CA  1 
ATOM   11050 C C   . TYR D 1 392 ? 102.746 115.881 138.682 1.00 68.46  ? 445 TYR D C   1 
ATOM   11051 O O   . TYR D 1 392 ? 102.031 116.159 137.713 1.00 64.91  ? 445 TYR D O   1 
ATOM   11052 C CB  . TYR D 1 392 ? 102.483 117.307 140.726 1.00 66.19  ? 445 TYR D CB  1 
ATOM   11053 C CG  . TYR D 1 392 ? 101.989 118.478 139.905 1.00 66.90  ? 445 TYR D CG  1 
ATOM   11054 C CD1 . TYR D 1 392 ? 100.654 118.856 139.934 1.00 71.84  ? 445 TYR D CD1 1 
ATOM   11055 C CD2 . TYR D 1 392 ? 102.859 119.205 139.104 1.00 69.80  ? 445 TYR D CD2 1 
ATOM   11056 C CE1 . TYR D 1 392 ? 100.199 119.926 139.185 1.00 76.82  ? 445 TYR D CE1 1 
ATOM   11057 C CE2 . TYR D 1 392 ? 102.412 120.275 138.352 1.00 72.79  ? 445 TYR D CE2 1 
ATOM   11058 C CZ  . TYR D 1 392 ? 101.083 120.632 138.396 1.00 76.53  ? 445 TYR D CZ  1 
ATOM   11059 O OH  . TYR D 1 392 ? 100.636 121.697 137.650 1.00 81.73  ? 445 TYR D OH  1 
ATOM   11060 N N   . TYR D 1 393 ? 104.019 115.516 138.538 1.00 69.40  ? 446 TYR D N   1 
ATOM   11061 C CA  . TYR D 1 393 ? 104.690 115.528 137.245 1.00 63.76  ? 446 TYR D CA  1 
ATOM   11062 C C   . TYR D 1 393 ? 104.803 114.147 136.613 1.00 71.21  ? 446 TYR D C   1 
ATOM   11063 O O   . TYR D 1 393 ? 105.533 113.989 135.630 1.00 75.07  ? 446 TYR D O   1 
ATOM   11064 C CB  . TYR D 1 393 ? 106.080 116.151 137.376 1.00 60.44  ? 446 TYR D CB  1 
ATOM   11065 C CG  . TYR D 1 393 ? 106.060 117.619 137.728 1.00 60.13  ? 446 TYR D CG  1 
ATOM   11066 C CD1 . TYR D 1 393 ? 105.698 118.572 136.789 1.00 63.75  ? 446 TYR D CD1 1 
ATOM   11067 C CD2 . TYR D 1 393 ? 106.409 118.052 138.998 1.00 62.55  ? 446 TYR D CD2 1 
ATOM   11068 C CE1 . TYR D 1 393 ? 105.679 119.914 137.104 1.00 65.02  ? 446 TYR D CE1 1 
ATOM   11069 C CE2 . TYR D 1 393 ? 106.393 119.393 139.322 1.00 66.11  ? 446 TYR D CE2 1 
ATOM   11070 C CZ  . TYR D 1 393 ? 106.027 120.319 138.372 1.00 66.52  ? 446 TYR D CZ  1 
ATOM   11071 O OH  . TYR D 1 393 ? 106.011 121.656 138.690 1.00 68.64  ? 446 TYR D OH  1 
ATOM   11072 N N   . VAL D 1 394 ? 104.111 113.148 137.150 1.00 76.82  ? 447 VAL D N   1 
ATOM   11073 C CA  . VAL D 1 394 ? 104.108 111.819 136.546 1.00 78.11  ? 447 VAL D CA  1 
ATOM   11074 C C   . VAL D 1 394 ? 102.677 111.315 136.401 1.00 79.16  ? 447 VAL D C   1 
ATOM   11075 O O   . VAL D 1 394 ? 101.858 111.473 137.306 1.00 75.57  ? 447 VAL D O   1 
ATOM   11076 C CB  . VAL D 1 394 ? 104.954 110.823 137.360 1.00 73.70  ? 447 VAL D CB  1 
ATOM   11077 C CG1 . VAL D 1 394 ? 104.729 109.406 136.857 1.00 71.10  ? 447 VAL D CG1 1 
ATOM   11078 C CG2 . VAL D 1 394 ? 106.429 111.186 137.284 1.00 60.97  ? 447 VAL D CG2 1 
ATOM   11079 N N   . ASN E 1 58  ? 99.010  127.835 70.504  1.00 128.28 ? 4   ASN E N   1 
ATOM   11080 C CA  . ASN E 1 58  ? 97.672  128.344 70.777  1.00 132.13 ? 4   ASN E CA  1 
ATOM   11081 C C   . ASN E 1 58  ? 97.003  127.524 71.873  1.00 133.76 ? 4   ASN E C   1 
ATOM   11082 O O   . ASN E 1 58  ? 96.305  128.064 72.732  1.00 131.30 ? 4   ASN E O   1 
ATOM   11083 C CB  . ASN E 1 58  ? 96.824  128.328 69.503  1.00 135.37 ? 4   ASN E CB  1 
ATOM   11084 C CG  . ASN E 1 58  ? 95.458  128.952 69.702  1.00 136.63 ? 4   ASN E CG  1 
ATOM   11085 O OD1 . ASN E 1 58  ? 95.304  130.171 69.626  1.00 138.55 ? 4   ASN E OD1 1 
ATOM   11086 N ND2 . ASN E 1 58  ? 94.457  128.118 69.954  1.00 133.18 ? 4   ASN E ND2 1 
ATOM   11087 N N   . ASP E 1 59  ? 97.224  126.217 71.834  1.00 139.28 ? 5   ASP E N   1 
ATOM   11088 C CA  . ASP E 1 59  ? 96.647  125.330 72.836  1.00 139.41 ? 5   ASP E CA  1 
ATOM   11089 C C   . ASP E 1 59  ? 97.388  125.484 74.159  1.00 137.71 ? 5   ASP E C   1 
ATOM   11090 O O   . ASP E 1 59  ? 98.623  125.540 74.169  1.00 132.86 ? 5   ASP E O   1 
ATOM   11091 C CB  . ASP E 1 59  ? 96.711  123.881 72.361  1.00 134.99 ? 5   ASP E CB  1 
ATOM   11092 C CG  . ASP E 1 59  ? 96.056  123.682 71.011  1.00 139.45 ? 5   ASP E CG  1 
ATOM   11093 O OD1 . ASP E 1 59  ? 95.111  124.433 70.690  1.00 140.12 ? 5   ASP E OD1 1 
ATOM   11094 O OD2 . ASP E 1 59  ? 96.486  122.775 70.269  1.00 141.26 ? 5   ASP E OD2 1 
ATOM   11095 N N   . PRO E 1 60  ? 96.678  125.570 75.287  1.00 138.66 ? 6   PRO E N   1 
ATOM   11096 C CA  . PRO E 1 60  ? 97.374  125.633 76.583  1.00 137.35 ? 6   PRO E CA  1 
ATOM   11097 C C   . PRO E 1 60  ? 98.244  124.420 76.858  1.00 137.06 ? 6   PRO E C   1 
ATOM   11098 O O   . PRO E 1 60  ? 99.286  124.551 77.513  1.00 134.56 ? 6   PRO E O   1 
ATOM   11099 C CB  . PRO E 1 60  ? 96.222  125.743 77.592  1.00 135.09 ? 6   PRO E CB  1 
ATOM   11100 C CG  . PRO E 1 60  ? 95.074  126.288 76.803  1.00 132.11 ? 6   PRO E CG  1 
ATOM   11101 C CD  . PRO E 1 60  ? 95.220  125.706 75.431  1.00 133.35 ? 6   PRO E CD  1 
ATOM   11102 N N   . GLY E 1 61  ? 97.850  123.241 76.377  1.00 136.34 ? 7   GLY E N   1 
ATOM   11103 C CA  . GLY E 1 61  ? 98.653  122.046 76.553  1.00 130.91 ? 7   GLY E CA  1 
ATOM   11104 C C   . GLY E 1 61  ? 99.849  121.936 75.635  1.00 127.60 ? 7   GLY E C   1 
ATOM   11105 O O   . GLY E 1 61  ? 100.690 121.054 75.837  1.00 120.47 ? 7   GLY E O   1 
ATOM   11106 N N   . ASN E 1 62  ? 99.945  122.808 74.634  1.00 128.50 ? 8   ASN E N   1 
ATOM   11107 C CA  . ASN E 1 62  ? 101.067 122.815 73.698  1.00 121.34 ? 8   ASN E CA  1 
ATOM   11108 C C   . ASN E 1 62  ? 102.258 123.452 74.401  1.00 117.05 ? 8   ASN E C   1 
ATOM   11109 O O   . ASN E 1 62  ? 102.471 124.664 74.341  1.00 115.69 ? 8   ASN E O   1 
ATOM   11110 C CB  . ASN E 1 62  ? 100.698 123.567 72.425  1.00 121.26 ? 8   ASN E CB  1 
ATOM   11111 C CG  . ASN E 1 62  ? 101.643 123.277 71.274  1.00 120.73 ? 8   ASN E CG  1 
ATOM   11112 O OD1 . ASN E 1 62  ? 102.744 122.763 71.468  1.00 117.56 ? 8   ASN E OD1 1 
ATOM   11113 N ND2 . ASN E 1 62  ? 101.211 123.611 70.063  1.00 128.94 ? 8   ASN E ND2 1 
ATOM   11114 N N   . MET E 1 63  ? 103.047 122.619 75.085  1.00 115.51 ? 9   MET E N   1 
ATOM   11115 C CA  . MET E 1 63  ? 104.208 123.128 75.806  1.00 110.52 ? 9   MET E CA  1 
ATOM   11116 C C   . MET E 1 63  ? 105.240 123.724 74.859  1.00 108.13 ? 9   MET E C   1 
ATOM   11117 O O   . MET E 1 63  ? 105.993 124.622 75.252  1.00 106.75 ? 9   MET E O   1 
ATOM   11118 C CB  . MET E 1 63  ? 104.835 122.017 76.648  1.00 107.64 ? 9   MET E CB  1 
ATOM   11119 C CG  . MET E 1 63  ? 103.915 121.469 77.726  1.00 108.10 ? 9   MET E CG  1 
ATOM   11120 S SD  . MET E 1 63  ? 104.681 120.165 78.706  1.00 113.32 ? 9   MET E SD  1 
ATOM   11121 C CE  . MET E 1 63  ? 106.103 121.030 79.364  1.00 107.87 ? 9   MET E CE  1 
ATOM   11122 N N   . SER E 1 64  ? 105.291 123.243 73.614  1.00 110.67 ? 10  SER E N   1 
ATOM   11123 C CA  . SER E 1 64  ? 106.170 123.855 72.623  1.00 112.10 ? 10  SER E CA  1 
ATOM   11124 C C   . SER E 1 64  ? 105.746 125.289 72.329  1.00 109.83 ? 10  SER E C   1 
ATOM   11125 O O   . SER E 1 64  ? 106.592 126.179 72.189  1.00 107.13 ? 10  SER E O   1 
ATOM   11126 C CB  . SER E 1 64  ? 106.180 123.021 71.343  1.00 116.66 ? 10  SER E CB  1 
ATOM   11127 O OG  . SER E 1 64  ? 104.887 122.952 70.768  1.00 117.70 ? 10  SER E OG  1 
ATOM   11128 N N   . PHE E 1 65  ? 104.437 125.531 72.235  1.00 111.49 ? 11  PHE E N   1 
ATOM   11129 C CA  . PHE E 1 65  ? 103.947 126.889 72.019  1.00 106.02 ? 11  PHE E CA  1 
ATOM   11130 C C   . PHE E 1 65  ? 104.286 127.795 73.197  1.00 101.08 ? 11  PHE E C   1 
ATOM   11131 O O   . PHE E 1 65  ? 104.663 128.957 73.008  1.00 102.32 ? 11  PHE E O   1 
ATOM   11132 C CB  . PHE E 1 65  ? 102.439 126.868 71.775  1.00 110.08 ? 11  PHE E CB  1 
ATOM   11133 C CG  . PHE E 1 65  ? 101.786 128.211 71.906  1.00 109.51 ? 11  PHE E CG  1 
ATOM   11134 C CD1 . PHE E 1 65  ? 101.952 129.175 70.927  1.00 109.10 ? 11  PHE E CD1 1 
ATOM   11135 C CD2 . PHE E 1 65  ? 100.998 128.507 73.005  1.00 109.09 ? 11  PHE E CD2 1 
ATOM   11136 C CE1 . PHE E 1 65  ? 101.348 130.411 71.044  1.00 108.18 ? 11  PHE E CE1 1 
ATOM   11137 C CE2 . PHE E 1 65  ? 100.392 129.739 73.128  1.00 108.14 ? 11  PHE E CE2 1 
ATOM   11138 C CZ  . PHE E 1 65  ? 100.567 130.693 72.146  1.00 108.57 ? 11  PHE E CZ  1 
ATOM   11139 N N   . VAL E 1 66  ? 104.145 127.285 74.422  1.00 99.99  ? 12  VAL E N   1 
ATOM   11140 C CA  . VAL E 1 66  ? 104.483 128.080 75.597  1.00 94.26  ? 12  VAL E CA  1 
ATOM   11141 C C   . VAL E 1 66  ? 105.976 128.381 75.626  1.00 92.32  ? 12  VAL E C   1 
ATOM   11142 O O   . VAL E 1 66  ? 106.393 129.492 75.978  1.00 93.56  ? 12  VAL E O   1 
ATOM   11143 C CB  . VAL E 1 66  ? 104.021 127.361 76.877  1.00 90.25  ? 12  VAL E CB  1 
ATOM   11144 C CG1 . VAL E 1 66  ? 104.303 128.217 78.096  1.00 83.94  ? 12  VAL E CG1 1 
ATOM   11145 C CG2 . VAL E 1 66  ? 102.542 127.027 76.786  1.00 90.50  ? 12  VAL E CG2 1 
ATOM   11146 N N   . LYS E 1 67  ? 106.804 127.400 75.262  1.00 89.16  ? 13  LYS E N   1 
ATOM   11147 C CA  . LYS E 1 67  ? 108.241 127.642 75.190  1.00 87.18  ? 13  LYS E CA  1 
ATOM   11148 C C   . LYS E 1 67  ? 108.566 128.697 74.143  1.00 93.00  ? 13  LYS E C   1 
ATOM   11149 O O   . LYS E 1 67  ? 109.426 129.556 74.364  1.00 94.63  ? 13  LYS E O   1 
ATOM   11150 C CB  . LYS E 1 67  ? 108.984 126.344 74.884  1.00 86.12  ? 13  LYS E CB  1 
ATOM   11151 C CG  . LYS E 1 67  ? 110.482 126.535 74.741  1.00 86.02  ? 13  LYS E CG  1 
ATOM   11152 C CD  . LYS E 1 67  ? 111.161 125.298 74.193  1.00 93.83  ? 13  LYS E CD  1 
ATOM   11153 C CE  . LYS E 1 67  ? 112.640 125.557 73.963  1.00 100.72 ? 13  LYS E CE  1 
ATOM   11154 N NZ  . LYS E 1 67  ? 113.328 124.376 73.381  1.00 108.57 ? 13  LYS E NZ  1 
ATOM   11155 N N   . GLU E 1 68  ? 107.894 128.641 72.991  1.00 99.26  ? 14  GLU E N   1 
ATOM   11156 C CA  . GLU E 1 68  ? 108.105 129.654 71.962  1.00 97.17  ? 14  GLU E CA  1 
ATOM   11157 C C   . GLU E 1 68  ? 107.702 131.035 72.462  1.00 92.20  ? 14  GLU E C   1 
ATOM   11158 O O   . GLU E 1 68  ? 108.402 132.022 72.212  1.00 91.11  ? 14  GLU E O   1 
ATOM   11159 C CB  . GLU E 1 68  ? 107.326 129.286 70.699  1.00 103.76 ? 14  GLU E CB  1 
ATOM   11160 C CG  . GLU E 1 68  ? 107.865 128.060 69.980  1.00 111.59 ? 14  GLU E CG  1 
ATOM   11161 C CD  . GLU E 1 68  ? 106.925 127.549 68.906  1.00 121.89 ? 14  GLU E CD  1 
ATOM   11162 O OE1 . GLU E 1 68  ? 105.792 128.066 68.809  1.00 123.16 ? 14  GLU E OE1 1 
ATOM   11163 O OE2 . GLU E 1 68  ? 107.319 126.626 68.162  1.00 122.47 ? 14  GLU E OE2 1 
ATOM   11164 N N   . THR E 1 69  ? 106.579 131.121 73.178  1.00 92.28  ? 15  THR E N   1 
ATOM   11165 C CA  . THR E 1 69  ? 106.146 132.401 73.730  1.00 88.47  ? 15  THR E CA  1 
ATOM   11166 C C   . THR E 1 69  ? 107.161 132.946 74.730  1.00 86.31  ? 15  THR E C   1 
ATOM   11167 O O   . THR E 1 69  ? 107.484 134.139 74.711  1.00 87.64  ? 15  THR E O   1 
ATOM   11168 C CB  . THR E 1 69  ? 104.774 132.250 74.388  1.00 83.17  ? 15  THR E CB  1 
ATOM   11169 O OG1 . THR E 1 69  ? 103.817 131.829 73.409  1.00 91.76  ? 15  THR E OG1 1 
ATOM   11170 C CG2 . THR E 1 69  ? 104.322 133.568 74.992  1.00 74.21  ? 15  THR E CG2 1 
ATOM   11171 N N   . VAL E 1 70  ? 107.686 132.084 75.602  1.00 84.60  ? 16  VAL E N   1 
ATOM   11172 C CA  . VAL E 1 70  ? 108.653 132.541 76.596  1.00 84.29  ? 16  VAL E CA  1 
ATOM   11173 C C   . VAL E 1 70  ? 109.955 132.968 75.925  1.00 87.23  ? 16  VAL E C   1 
ATOM   11174 O O   . VAL E 1 70  ? 110.568 133.973 76.310  1.00 86.00  ? 16  VAL E O   1 
ATOM   11175 C CB  . VAL E 1 70  ? 108.886 131.453 77.660  1.00 81.46  ? 16  VAL E CB  1 
ATOM   11176 C CG1 . VAL E 1 70  ? 109.944 131.900 78.652  1.00 81.14  ? 16  VAL E CG1 1 
ATOM   11177 C CG2 . VAL E 1 70  ? 107.588 131.144 78.384  1.00 74.40  ? 16  VAL E CG2 1 
ATOM   11178 N N   . ASP E 1 71  ? 110.402 132.215 74.916  1.00 87.46  ? 17  ASP E N   1 
ATOM   11179 C CA  . ASP E 1 71  ? 111.610 132.594 74.190  1.00 86.64  ? 17  ASP E CA  1 
ATOM   11180 C C   . ASP E 1 71  ? 111.417 133.911 73.453  1.00 82.30  ? 17  ASP E C   1 
ATOM   11181 O O   . ASP E 1 71  ? 112.355 134.706 73.331  1.00 82.87  ? 17  ASP E O   1 
ATOM   11182 C CB  . ASP E 1 71  ? 112.009 131.488 73.214  1.00 95.74  ? 17  ASP E CB  1 
ATOM   11183 C CG  . ASP E 1 71  ? 112.363 130.193 73.914  1.00 100.07 ? 17  ASP E CG  1 
ATOM   11184 O OD1 . ASP E 1 71  ? 112.178 130.111 75.146  1.00 96.98  ? 17  ASP E OD1 1 
ATOM   11185 O OD2 . ASP E 1 71  ? 112.830 129.258 73.232  1.00 102.91 ? 17  ASP E OD2 1 
ATOM   11186 N N   . LYS E 1 72  ? 110.209 134.153 72.943  1.00 82.36  ? 18  LYS E N   1 
ATOM   11187 C CA  . LYS E 1 72  ? 109.897 135.448 72.352  1.00 83.50  ? 18  LYS E CA  1 
ATOM   11188 C C   . LYS E 1 72  ? 109.956 136.552 73.399  1.00 83.02  ? 18  LYS E C   1 
ATOM   11189 O O   . LYS E 1 72  ? 110.443 137.655 73.126  1.00 82.75  ? 18  LYS E O   1 
ATOM   11190 C CB  . LYS E 1 72  ? 108.517 135.397 71.697  1.00 85.00  ? 18  LYS E CB  1 
ATOM   11191 C CG  . LYS E 1 72  ? 108.075 136.691 71.042  1.00 83.31  ? 18  LYS E CG  1 
ATOM   11192 C CD  . LYS E 1 72  ? 106.697 136.535 70.421  1.00 78.40  ? 18  LYS E CD  1 
ATOM   11193 C CE  . LYS E 1 72  ? 106.250 137.815 69.737  1.00 80.70  ? 18  LYS E CE  1 
ATOM   11194 N NZ  . LYS E 1 72  ? 104.917 137.664 69.092  1.00 80.91  ? 18  LYS E NZ  1 
ATOM   11195 N N   . LEU E 1 73  ? 109.457 136.270 74.605  1.00 80.16  ? 19  LEU E N   1 
ATOM   11196 C CA  . LEU E 1 73  ? 109.513 137.252 75.683  1.00 72.54  ? 19  LEU E CA  1 
ATOM   11197 C C   . LEU E 1 73  ? 110.950 137.607 76.039  1.00 78.96  ? 19  LEU E C   1 
ATOM   11198 O O   . LEU E 1 73  ? 111.278 138.784 76.228  1.00 80.81  ? 19  LEU E O   1 
ATOM   11199 C CB  . LEU E 1 73  ? 108.783 136.724 76.918  1.00 70.24  ? 19  LEU E CB  1 
ATOM   11200 C CG  . LEU E 1 73  ? 107.266 136.590 76.831  1.00 74.12  ? 19  LEU E CG  1 
ATOM   11201 C CD1 . LEU E 1 73  ? 106.682 136.290 78.202  1.00 70.52  ? 19  LEU E CD1 1 
ATOM   11202 C CD2 . LEU E 1 73  ? 106.661 137.851 76.248  1.00 70.63  ? 19  LEU E CD2 1 
ATOM   11203 N N   . LEU E 1 74  ? 111.818 136.606 76.141  1.00 80.94  ? 20  LEU E N   1 
ATOM   11204 C CA  . LEU E 1 74  ? 113.202 136.830 76.537  1.00 78.36  ? 20  LEU E CA  1 
ATOM   11205 C C   . LEU E 1 74  ? 114.123 137.134 75.363  1.00 78.94  ? 20  LEU E C   1 
ATOM   11206 O O   . LEU E 1 74  ? 115.321 137.348 75.576  1.00 77.17  ? 20  LEU E O   1 
ATOM   11207 C CB  . LEU E 1 74  ? 113.738 135.618 77.305  1.00 73.37  ? 20  LEU E CB  1 
ATOM   11208 C CG  . LEU E 1 74  ? 113.089 135.331 78.659  1.00 75.00  ? 20  LEU E CG  1 
ATOM   11209 C CD1 . LEU E 1 74  ? 113.954 134.385 79.474  1.00 78.68  ? 20  LEU E CD1 1 
ATOM   11210 C CD2 . LEU E 1 74  ? 112.845 136.622 79.415  1.00 74.72  ? 20  LEU E CD2 1 
ATOM   11211 N N   . LYS E 1 75  ? 113.604 137.158 74.138  1.00 81.81  ? 21  LYS E N   1 
ATOM   11212 C CA  . LYS E 1 75  ? 114.438 137.437 72.976  1.00 83.36  ? 21  LYS E CA  1 
ATOM   11213 C C   . LYS E 1 75  ? 114.752 138.926 72.917  1.00 82.50  ? 21  LYS E C   1 
ATOM   11214 O O   . LYS E 1 75  ? 113.848 139.753 72.756  1.00 83.20  ? 21  LYS E O   1 
ATOM   11215 C CB  . LYS E 1 75  ? 113.738 136.982 71.699  1.00 90.60  ? 21  LYS E CB  1 
ATOM   11216 C CG  . LYS E 1 75  ? 114.664 136.776 70.514  1.00 88.89  ? 21  LYS E CG  1 
ATOM   11217 C CD  . LYS E 1 75  ? 113.919 136.142 69.352  1.00 95.31  ? 21  LYS E CD  1 
ATOM   11218 C CE  . LYS E 1 75  ? 114.862 135.764 68.223  1.00 103.77 ? 21  LYS E CE  1 
ATOM   11219 N NZ  . LYS E 1 75  ? 114.138 135.092 67.109  1.00 105.78 ? 21  LYS E NZ  1 
ATOM   11220 N N   . GLY E 1 76  ? 116.031 139.268 73.048  1.00 77.67  ? 22  GLY E N   1 
ATOM   11221 C CA  . GLY E 1 76  ? 116.448 140.652 73.080  1.00 80.04  ? 22  GLY E CA  1 
ATOM   11222 C C   . GLY E 1 76  ? 116.241 141.349 74.404  1.00 82.32  ? 22  GLY E C   1 
ATOM   11223 O O   . GLY E 1 76  ? 116.523 142.550 74.503  1.00 83.58  ? 22  GLY E O   1 
ATOM   11224 N N   . TYR E 1 77  ? 115.754 140.641 75.420  1.00 80.63  ? 23  TYR E N   1 
ATOM   11225 C CA  . TYR E 1 77  ? 115.558 141.237 76.733  1.00 74.42  ? 23  TYR E CA  1 
ATOM   11226 C C   . TYR E 1 77  ? 116.899 141.631 77.340  1.00 75.27  ? 23  TYR E C   1 
ATOM   11227 O O   . TYR E 1 77  ? 117.878 140.885 77.262  1.00 78.29  ? 23  TYR E O   1 
ATOM   11228 C CB  . TYR E 1 77  ? 114.830 140.250 77.646  1.00 70.73  ? 23  TYR E CB  1 
ATOM   11229 C CG  . TYR E 1 77  ? 114.379 140.829 78.965  1.00 64.92  ? 23  TYR E CG  1 
ATOM   11230 C CD1 . TYR E 1 77  ? 115.219 140.830 80.069  1.00 63.01  ? 23  TYR E CD1 1 
ATOM   11231 C CD2 . TYR E 1 77  ? 113.108 141.363 79.110  1.00 63.96  ? 23  TYR E CD2 1 
ATOM   11232 C CE1 . TYR E 1 77  ? 114.810 141.354 81.276  1.00 61.34  ? 23  TYR E CE1 1 
ATOM   11233 C CE2 . TYR E 1 77  ? 112.689 141.888 80.313  1.00 61.73  ? 23  TYR E CE2 1 
ATOM   11234 C CZ  . TYR E 1 77  ? 113.544 141.882 81.393  1.00 60.43  ? 23  TYR E CZ  1 
ATOM   11235 O OH  . TYR E 1 77  ? 113.131 142.406 82.596  1.00 62.44  ? 23  TYR E OH  1 
ATOM   11236 N N   . ASP E 1 78  ? 116.939 142.813 77.951  1.00 76.25  ? 24  ASP E N   1 
ATOM   11237 C CA  . ASP E 1 78  ? 118.148 143.340 78.576  1.00 75.08  ? 24  ASP E CA  1 
ATOM   11238 C C   . ASP E 1 78  ? 117.892 143.475 80.071  1.00 67.30  ? 24  ASP E C   1 
ATOM   11239 O O   . ASP E 1 78  ? 117.054 144.279 80.492  1.00 60.85  ? 24  ASP E O   1 
ATOM   11240 C CB  . ASP E 1 78  ? 118.544 144.682 77.958  1.00 74.64  ? 24  ASP E CB  1 
ATOM   11241 C CG  . ASP E 1 78  ? 119.991 145.048 78.232  1.00 77.07  ? 24  ASP E CG  1 
ATOM   11242 O OD1 . ASP E 1 78  ? 120.671 144.296 78.960  1.00 75.35  ? 24  ASP E OD1 1 
ATOM   11243 O OD2 . ASP E 1 78  ? 120.451 146.086 77.712  1.00 80.77  ? 24  ASP E OD2 1 
ATOM   11244 N N   . ILE E 1 79  ? 118.614 142.687 80.871  1.00 66.12  ? 25  ILE E N   1 
ATOM   11245 C CA  . ILE E 1 79  ? 118.450 142.730 82.319  1.00 64.17  ? 25  ILE E CA  1 
ATOM   11246 C C   . ILE E 1 79  ? 119.053 143.979 82.938  1.00 67.28  ? 25  ILE E C   1 
ATOM   11247 O O   . ILE E 1 79  ? 118.789 144.269 84.110  1.00 70.00  ? 25  ILE E O   1 
ATOM   11248 C CB  . ILE E 1 79  ? 119.073 141.480 82.973  1.00 63.12  ? 25  ILE E CB  1 
ATOM   11249 C CG1 . ILE E 1 79  ? 120.596 141.605 83.031  1.00 68.51  ? 25  ILE E CG1 1 
ATOM   11250 C CG2 . ILE E 1 79  ? 118.689 140.237 82.197  1.00 65.53  ? 25  ILE E CG2 1 
ATOM   11251 C CD1 . ILE E 1 79  ? 121.284 140.411 83.660  1.00 67.43  ? 25  ILE E CD1 1 
ATOM   11252 N N   . ARG E 1 80  ? 119.852 144.727 82.180  1.00 64.85  ? 26  ARG E N   1 
ATOM   11253 C CA  . ARG E 1 80  ? 120.507 145.921 82.694  1.00 58.89  ? 26  ARG E CA  1 
ATOM   11254 C C   . ARG E 1 80  ? 119.606 147.145 82.685  1.00 53.27  ? 26  ARG E C   1 
ATOM   11255 O O   . ARG E 1 80  ? 119.964 148.160 83.291  1.00 51.33  ? 26  ARG E O   1 
ATOM   11256 C CB  . ARG E 1 80  ? 121.768 146.204 81.879  1.00 59.04  ? 26  ARG E CB  1 
ATOM   11257 C CG  . ARG E 1 80  ? 122.756 145.057 81.888  1.00 63.56  ? 26  ARG E CG  1 
ATOM   11258 C CD  . ARG E 1 80  ? 123.782 145.200 80.785  1.00 67.60  ? 26  ARG E CD  1 
ATOM   11259 N NE  . ARG E 1 80  ? 123.168 145.162 79.464  1.00 69.50  ? 26  ARG E NE  1 
ATOM   11260 C CZ  . ARG E 1 80  ? 123.848 145.107 78.327  1.00 75.43  ? 26  ARG E CZ  1 
ATOM   11261 N NH1 . ARG E 1 80  ? 125.170 145.071 78.314  1.00 75.35  ? 26  ARG E NH1 1 
ATOM   11262 N NH2 . ARG E 1 80  ? 123.184 145.084 77.175  1.00 82.88  ? 26  ARG E NH2 1 
ATOM   11263 N N   . LEU E 1 81  ? 118.456 147.077 82.023  1.00 53.78  ? 27  LEU E N   1 
ATOM   11264 C CA  . LEU E 1 81  ? 117.559 148.213 81.878  1.00 53.38  ? 27  LEU E CA  1 
ATOM   11265 C C   . LEU E 1 81  ? 116.253 147.932 82.605  1.00 51.50  ? 27  LEU E C   1 
ATOM   11266 O O   . LEU E 1 81  ? 115.603 146.913 82.353  1.00 52.85  ? 27  LEU E O   1 
ATOM   11267 C CB  . LEU E 1 81  ? 117.290 148.508 80.402  1.00 59.79  ? 27  LEU E CB  1 
ATOM   11268 C CG  . LEU E 1 81  ? 118.526 148.754 79.536  1.00 58.16  ? 27  LEU E CG  1 
ATOM   11269 C CD1 . LEU E 1 81  ? 118.123 148.960 78.089  1.00 56.35  ? 27  LEU E CD1 1 
ATOM   11270 C CD2 . LEU E 1 81  ? 119.306 149.949 80.053  1.00 59.86  ? 27  LEU E CD2 1 
ATOM   11271 N N   . ARG E 1 82  ? 115.873 148.840 83.498  1.00 53.50  ? 28  ARG E N   1 
ATOM   11272 C CA  . ARG E 1 82  ? 114.624 148.712 84.223  1.00 51.88  ? 28  ARG E CA  1 
ATOM   11273 C C   . ARG E 1 82  ? 113.440 148.915 83.281  1.00 55.14  ? 28  ARG E C   1 
ATOM   11274 O O   . ARG E 1 82  ? 113.578 149.526 82.219  1.00 64.68  ? 28  ARG E O   1 
ATOM   11275 C CB  . ARG E 1 82  ? 114.571 149.728 85.359  1.00 49.61  ? 28  ARG E CB  1 
ATOM   11276 C CG  . ARG E 1 82  ? 114.588 151.165 84.887  1.00 54.06  ? 28  ARG E CG  1 
ATOM   11277 C CD  . ARG E 1 82  ? 114.455 152.123 86.049  1.00 57.77  ? 28  ARG E CD  1 
ATOM   11278 N NE  . ARG E 1 82  ? 114.284 153.499 85.603  1.00 57.48  ? 28  ARG E NE  1 
ATOM   11279 C CZ  . ARG E 1 82  ? 113.110 154.068 85.371  1.00 58.90  ? 28  ARG E CZ  1 
ATOM   11280 N NH1 . ARG E 1 82  ? 111.978 153.401 85.525  1.00 59.61  ? 28  ARG E NH1 1 
ATOM   11281 N NH2 . ARG E 1 82  ? 113.071 155.337 84.977  1.00 57.39  ? 28  ARG E NH2 1 
ATOM   11282 N N   . PRO E 1 83  ? 112.266 148.398 83.644  1.00 50.91  ? 29  PRO E N   1 
ATOM   11283 C CA  . PRO E 1 83  ? 111.077 148.629 82.817  1.00 59.29  ? 29  PRO E CA  1 
ATOM   11284 C C   . PRO E 1 83  ? 110.780 150.114 82.681  1.00 69.00  ? 29  PRO E C   1 
ATOM   11285 O O   . PRO E 1 83  ? 110.892 150.878 83.641  1.00 70.34  ? 29  PRO E O   1 
ATOM   11286 C CB  . PRO E 1 83  ? 109.967 147.900 83.581  1.00 55.45  ? 29  PRO E CB  1 
ATOM   11287 C CG  . PRO E 1 83  ? 110.676 146.875 84.386  1.00 53.20  ? 29  PRO E CG  1 
ATOM   11288 C CD  . PRO E 1 83  ? 111.987 147.488 84.765  1.00 49.47  ? 29  PRO E CD  1 
ATOM   11289 N N   . ASP E 1 84  ? 110.379 150.510 81.473  1.00 69.32  ? 30  ASP E N   1 
ATOM   11290 C CA  . ASP E 1 84  ? 110.155 151.913 81.131  1.00 67.10  ? 30  ASP E CA  1 
ATOM   11291 C C   . ASP E 1 84  ? 111.378 152.760 81.468  1.00 66.58  ? 30  ASP E C   1 
ATOM   11292 O O   . ASP E 1 84  ? 111.283 153.819 82.091  1.00 72.51  ? 30  ASP E O   1 
ATOM   11293 C CB  . ASP E 1 84  ? 108.901 152.458 81.815  1.00 72.39  ? 30  ASP E CB  1 
ATOM   11294 C CG  . ASP E 1 84  ? 107.629 152.034 81.114  1.00 89.44  ? 30  ASP E CG  1 
ATOM   11295 O OD1 . ASP E 1 84  ? 107.720 151.262 80.136  1.00 95.73  ? 30  ASP E OD1 1 
ATOM   11296 O OD2 . ASP E 1 84  ? 106.539 152.474 81.534  1.00 87.50  ? 30  ASP E OD2 1 
ATOM   11297 N N   . PHE E 1 85  ? 112.545 152.270 81.055  1.00 61.27  ? 31  PHE E N   1 
ATOM   11298 C CA  . PHE E 1 85  ? 113.779 153.015 81.251  1.00 59.16  ? 31  PHE E CA  1 
ATOM   11299 C C   . PHE E 1 85  ? 113.698 154.360 80.541  1.00 66.82  ? 31  PHE E C   1 
ATOM   11300 O O   . PHE E 1 85  ? 113.207 154.459 79.414  1.00 74.72  ? 31  PHE E O   1 
ATOM   11301 C CB  . PHE E 1 85  ? 114.971 152.215 80.729  1.00 53.84  ? 31  PHE E CB  1 
ATOM   11302 C CG  . PHE E 1 85  ? 116.301 152.794 81.107  1.00 54.68  ? 31  PHE E CG  1 
ATOM   11303 C CD1 . PHE E 1 85  ? 116.910 153.748 80.311  1.00 56.07  ? 31  PHE E CD1 1 
ATOM   11304 C CD2 . PHE E 1 85  ? 116.944 152.383 82.261  1.00 59.89  ? 31  PHE E CD2 1 
ATOM   11305 C CE1 . PHE E 1 85  ? 118.132 154.281 80.658  1.00 51.82  ? 31  PHE E CE1 1 
ATOM   11306 C CE2 . PHE E 1 85  ? 118.168 152.911 82.613  1.00 62.41  ? 31  PHE E CE2 1 
ATOM   11307 C CZ  . PHE E 1 85  ? 118.763 153.862 81.811  1.00 56.80  ? 31  PHE E CZ  1 
ATOM   11308 N N   . GLY E 1 86  ? 114.184 155.402 81.211  1.00 65.94  ? 32  GLY E N   1 
ATOM   11309 C CA  . GLY E 1 86  ? 114.088 156.736 80.660  1.00 68.82  ? 32  GLY E CA  1 
ATOM   11310 C C   . GLY E 1 86  ? 112.708 157.343 80.727  1.00 68.71  ? 32  GLY E C   1 
ATOM   11311 O O   . GLY E 1 86  ? 112.417 158.279 79.979  1.00 71.33  ? 32  GLY E O   1 
ATOM   11312 N N   . GLY E 1 87  ? 111.844 156.838 81.603  1.00 64.61  ? 33  GLY E N   1 
ATOM   11313 C CA  . GLY E 1 87  ? 110.501 157.347 81.724  1.00 69.08  ? 33  GLY E CA  1 
ATOM   11314 C C   . GLY E 1 87  ? 110.022 157.396 83.159  1.00 71.96  ? 33  GLY E C   1 
ATOM   11315 O O   . GLY E 1 87  ? 110.796 157.636 84.092  1.00 70.82  ? 33  GLY E O   1 
ATOM   11316 N N   . PRO E 1 88  ? 108.728 157.171 83.361  1.00 73.38  ? 34  PRO E N   1 
ATOM   11317 C CA  . PRO E 1 88  ? 108.155 157.245 84.708  1.00 72.12  ? 34  PRO E CA  1 
ATOM   11318 C C   . PRO E 1 88  ? 108.685 156.131 85.591  1.00 67.79  ? 34  PRO E C   1 
ATOM   11319 O O   . PRO E 1 88  ? 109.105 155.076 85.093  1.00 66.18  ? 34  PRO E O   1 
ATOM   11320 C CB  . PRO E 1 88  ? 106.646 157.089 84.459  1.00 69.33  ? 34  PRO E CB  1 
ATOM   11321 C CG  . PRO E 1 88  ? 106.455 157.400 83.009  1.00 67.26  ? 34  PRO E CG  1 
ATOM   11322 C CD  . PRO E 1 88  ? 107.702 156.927 82.337  1.00 68.88  ? 34  PRO E CD  1 
ATOM   11323 N N   . PRO E 1 89  ? 108.691 156.331 86.906  1.00 65.11  ? 35  PRO E N   1 
ATOM   11324 C CA  . PRO E 1 89  ? 109.129 155.265 87.812  1.00 61.52  ? 35  PRO E CA  1 
ATOM   11325 C C   . PRO E 1 89  ? 108.190 154.072 87.774  1.00 62.20  ? 35  PRO E C   1 
ATOM   11326 O O   . PRO E 1 89  ? 106.985 154.203 87.549  1.00 66.03  ? 35  PRO E O   1 
ATOM   11327 C CB  . PRO E 1 89  ? 109.111 155.941 89.188  1.00 63.80  ? 35  PRO E CB  1 
ATOM   11328 C CG  . PRO E 1 89  ? 108.126 157.051 89.042  1.00 68.08  ? 35  PRO E CG  1 
ATOM   11329 C CD  . PRO E 1 89  ? 108.291 157.545 87.636  1.00 70.17  ? 35  PRO E CD  1 
ATOM   11330 N N   . VAL E 1 90  ? 108.761 152.894 88.005  1.00 61.60  ? 36  VAL E N   1 
ATOM   11331 C CA  . VAL E 1 90  ? 107.996 151.653 88.040  1.00 62.35  ? 36  VAL E CA  1 
ATOM   11332 C C   . VAL E 1 90  ? 107.542 151.410 89.474  1.00 60.48  ? 36  VAL E C   1 
ATOM   11333 O O   . VAL E 1 90  ? 108.362 151.356 90.396  1.00 57.51  ? 36  VAL E O   1 
ATOM   11334 C CB  . VAL E 1 90  ? 108.822 150.473 87.505  1.00 59.99  ? 36  VAL E CB  1 
ATOM   11335 C CG1 . VAL E 1 90  ? 110.243 150.517 88.046  1.00 55.33  ? 36  VAL E CG1 1 
ATOM   11336 C CG2 . VAL E 1 90  ? 108.154 149.156 87.858  1.00 59.54  ? 36  VAL E CG2 1 
ATOM   11337 N N   . CYS E 1 91  ? 106.232 151.273 89.664  1.00 57.29  ? 37  CYS E N   1 
ATOM   11338 C CA  . CYS E 1 91  ? 105.658 151.118 90.997  1.00 57.90  ? 37  CYS E CA  1 
ATOM   11339 C C   . CYS E 1 91  ? 105.788 149.664 91.432  1.00 55.59  ? 37  CYS E C   1 
ATOM   11340 O O   . CYS E 1 91  ? 105.140 148.778 90.865  1.00 57.07  ? 37  CYS E O   1 
ATOM   11341 C CB  . CYS E 1 91  ? 104.201 151.567 91.005  1.00 59.68  ? 37  CYS E CB  1 
ATOM   11342 S SG  . CYS E 1 91  ? 103.952 153.290 90.524  1.00 84.61  ? 37  CYS E SG  1 
ATOM   11343 N N   . VAL E 1 92  ? 106.621 149.418 92.436  1.00 47.49  ? 38  VAL E N   1 
ATOM   11344 C CA  . VAL E 1 92  ? 106.858 148.079 92.960  1.00 40.94  ? 38  VAL E CA  1 
ATOM   11345 C C   . VAL E 1 92  ? 106.087 147.962 94.270  1.00 42.35  ? 38  VAL E C   1 
ATOM   11346 O O   . VAL E 1 92  ? 106.528 148.457 95.310  1.00 45.79  ? 38  VAL E O   1 
ATOM   11347 C CB  . VAL E 1 92  ? 108.351 147.805 93.158  1.00 38.81  ? 38  VAL E CB  1 
ATOM   11348 C CG1 . VAL E 1 92  ? 108.565 146.418 93.736  1.00 36.72  ? 38  VAL E CG1 1 
ATOM   11349 C CG2 . VAL E 1 92  ? 109.096 147.958 91.844  1.00 43.19  ? 38  VAL E CG2 1 
ATOM   11350 N N   . GLY E 1 93  ? 104.928 147.307 94.226  1.00 39.33  ? 39  GLY E N   1 
ATOM   11351 C CA  . GLY E 1 93  ? 104.206 147.010 95.446  1.00 38.93  ? 39  GLY E CA  1 
ATOM   11352 C C   . GLY E 1 93  ? 104.828 145.843 96.187  1.00 36.68  ? 39  GLY E C   1 
ATOM   11353 O O   . GLY E 1 93  ? 105.412 144.941 95.595  1.00 39.64  ? 39  GLY E O   1 
ATOM   11354 N N   . MET E 1 94  ? 104.719 145.869 97.509  1.00 35.79  ? 40  MET E N   1 
ATOM   11355 C CA  . MET E 1 94  ? 105.378 144.869 98.334  1.00 35.54  ? 40  MET E CA  1 
ATOM   11356 C C   . MET E 1 94  ? 104.436 144.326 99.393  1.00 37.79  ? 40  MET E C   1 
ATOM   11357 O O   . MET E 1 94  ? 103.639 145.069 99.972  1.00 47.25  ? 40  MET E O   1 
ATOM   11358 C CB  . MET E 1 94  ? 106.618 145.442 99.016  1.00 32.80  ? 40  MET E CB  1 
ATOM   11359 C CG  . MET E 1 94  ? 107.677 145.921 98.056  1.00 36.02  ? 40  MET E CG  1 
ATOM   11360 S SD  . MET E 1 94  ? 109.174 146.426 98.905  1.00 62.79  ? 40  MET E SD  1 
ATOM   11361 C CE  . MET E 1 94  ? 110.159 146.956 97.515  1.00 52.25  ? 40  MET E CE  1 
ATOM   11362 N N   A ASN E 1 95  ? 104.545 143.019 99.636  0.50 35.57  ? 41  ASN E N   1 
ATOM   11363 N N   B ASN E 1 95  ? 104.528 143.027 99.647  0.50 35.68  ? 41  ASN E N   1 
ATOM   11364 C CA  A ASN E 1 95  ? 103.826 142.325 100.693 0.50 37.33  ? 41  ASN E CA  1 
ATOM   11365 C CA  B ASN E 1 95  ? 103.828 142.445 100.779 0.50 37.19  ? 41  ASN E CA  1 
ATOM   11366 C C   A ASN E 1 95  ? 104.813 141.510 101.515 0.50 36.88  ? 41  ASN E C   1 
ATOM   11367 C C   B ASN E 1 95  ? 104.766 141.497 101.508 0.50 37.07  ? 41  ASN E C   1 
ATOM   11368 O O   A ASN E 1 95  ? 105.840 141.054 101.003 0.50 36.96  ? 41  ASN E O   1 
ATOM   11369 O O   B ASN E 1 95  ? 105.724 140.969 100.939 0.50 37.08  ? 41  ASN E O   1 
ATOM   11370 C CB  A ASN E 1 95  ? 102.749 141.393 100.130 0.50 39.27  ? 41  ASN E CB  1 
ATOM   11371 C CB  B ASN E 1 95  ? 102.532 141.737 100.359 0.50 39.06  ? 41  ASN E CB  1 
ATOM   11372 C CG  A ASN E 1 95  ? 101.907 142.055 99.064  0.50 41.19  ? 41  ASN E CG  1 
ATOM   11373 C CG  B ASN E 1 95  ? 102.714 140.848 99.153  0.50 40.42  ? 41  ASN E CG  1 
ATOM   11374 O OD1 A ASN E 1 95  ? 101.911 141.637 97.905  0.50 42.40  ? 41  ASN E OD1 1 
ATOM   11375 O OD1 B ASN E 1 95  ? 102.672 141.311 98.013  0.50 41.85  ? 41  ASN E OD1 1 
ATOM   11376 N ND2 A ASN E 1 95  ? 101.177 143.093 99.448  0.50 42.46  ? 41  ASN E ND2 1 
ATOM   11377 N ND2 B ASN E 1 95  ? 102.899 139.558 99.395  0.50 40.33  ? 41  ASN E ND2 1 
ATOM   11378 N N   . ILE E 1 96  ? 104.497 141.322 102.795 1.00 34.98  ? 42  ILE E N   1 
ATOM   11379 C CA  . ILE E 1 96  ? 105.314 140.502 103.678 1.00 33.49  ? 42  ILE E CA  1 
ATOM   11380 C C   . ILE E 1 96  ? 104.394 139.576 104.456 1.00 40.56  ? 42  ILE E C   1 
ATOM   11381 O O   . ILE E 1 96  ? 103.381 140.019 105.005 1.00 49.98  ? 42  ILE E O   1 
ATOM   11382 C CB  . ILE E 1 96  ? 106.161 141.357 104.639 1.00 35.42  ? 42  ILE E CB  1 
ATOM   11383 C CG1 . ILE E 1 96  ? 107.179 142.189 103.860 1.00 34.12  ? 42  ILE E CG1 1 
ATOM   11384 C CG2 . ILE E 1 96  ? 106.861 140.478 105.659 1.00 38.81  ? 42  ILE E CG2 1 
ATOM   11385 C CD1 . ILE E 1 96  ? 108.055 143.051 104.731 1.00 35.45  ? 42  ILE E CD1 1 
ATOM   11386 N N   . ASP E 1 97  ? 104.745 138.297 104.503 1.00 42.38  ? 43  ASP E N   1 
ATOM   11387 C CA  . ASP E 1 97  ? 104.063 137.321 105.346 1.00 48.33  ? 43  ASP E CA  1 
ATOM   11388 C C   . ASP E 1 97  ? 105.075 136.817 106.364 1.00 48.98  ? 43  ASP E C   1 
ATOM   11389 O O   . ASP E 1 97  ? 105.964 136.034 106.023 1.00 49.78  ? 43  ASP E O   1 
ATOM   11390 C CB  . ASP E 1 97  ? 103.493 136.176 104.513 1.00 49.71  ? 43  ASP E CB  1 
ATOM   11391 C CG  . ASP E 1 97  ? 102.709 135.183 105.346 1.00 65.04  ? 43  ASP E CG  1 
ATOM   11392 O OD1 . ASP E 1 97  ? 102.391 135.495 106.512 1.00 66.78  ? 43  ASP E OD1 1 
ATOM   11393 O OD2 . ASP E 1 97  ? 102.414 134.083 104.835 1.00 75.93  ? 43  ASP E OD2 1 
ATOM   11394 N N   . ILE E 1 98  ? 104.946 137.264 107.609 1.00 47.69  ? 44  ILE E N   1 
ATOM   11395 C CA  . ILE E 1 98  ? 105.931 136.949 108.638 1.00 45.60  ? 44  ILE E CA  1 
ATOM   11396 C C   . ILE E 1 98  ? 105.663 135.537 109.147 1.00 49.48  ? 44  ILE E C   1 
ATOM   11397 O O   . ILE E 1 98  ? 104.633 135.276 109.770 1.00 54.27  ? 44  ILE E O   1 
ATOM   11398 C CB  . ILE E 1 98  ? 105.892 137.968 109.779 1.00 44.51  ? 44  ILE E CB  1 
ATOM   11399 C CG1 . ILE E 1 98  ? 106.470 139.302 109.307 1.00 42.52  ? 44  ILE E CG1 1 
ATOM   11400 C CG2 . ILE E 1 98  ? 106.648 137.442 110.985 1.00 45.44  ? 44  ILE E CG2 1 
ATOM   11401 C CD1 . ILE E 1 98  ? 106.434 140.381 110.352 1.00 47.09  ? 44  ILE E CD1 1 
ATOM   11402 N N   . ALA E 1 99  ? 106.591 134.617 108.872 1.00 48.48  ? 45  ALA E N   1 
ATOM   11403 C CA  . ALA E 1 99  ? 106.433 133.255 109.363 1.00 47.80  ? 45  ALA E CA  1 
ATOM   11404 C C   . ALA E 1 99  ? 106.711 133.173 110.858 1.00 55.56  ? 45  ALA E C   1 
ATOM   11405 O O   . ALA E 1 99  ? 105.975 132.506 111.594 1.00 71.63  ? 45  ALA E O   1 
ATOM   11406 C CB  . ALA E 1 99  ? 107.349 132.307 108.592 1.00 43.86  ? 45  ALA E CB  1 
ATOM   11407 N N   . SER E 1 100 ? 107.755 133.854 111.328 1.00 50.86  ? 46  SER E N   1 
ATOM   11408 C CA  . SER E 1 100 ? 108.129 133.801 112.735 1.00 56.03  ? 46  SER E CA  1 
ATOM   11409 C C   . SER E 1 100 ? 109.182 134.861 113.022 1.00 55.90  ? 46  SER E C   1 
ATOM   11410 O O   . SER E 1 100 ? 109.911 135.297 112.127 1.00 55.70  ? 46  SER E O   1 
ATOM   11411 C CB  . SER E 1 100 ? 108.663 132.419 113.122 1.00 59.94  ? 46  SER E CB  1 
ATOM   11412 O OG  . SER E 1 100 ? 109.858 132.124 112.419 1.00 58.08  ? 46  SER E OG  1 
ATOM   11413 N N   . ILE E 1 101 ? 109.247 135.268 114.286 1.00 56.90  ? 47  ILE E N   1 
ATOM   11414 C CA  . ILE E 1 101 ? 110.355 136.050 114.824 1.00 53.64  ? 47  ILE E CA  1 
ATOM   11415 C C   . ILE E 1 101 ? 111.149 135.113 115.722 1.00 60.73  ? 47  ILE E C   1 
ATOM   11416 O O   . ILE E 1 101 ? 110.694 134.755 116.815 1.00 64.34  ? 47  ILE E O   1 
ATOM   11417 C CB  . ILE E 1 101 ? 109.873 137.286 115.594 1.00 43.62  ? 47  ILE E CB  1 
ATOM   11418 C CG1 . ILE E 1 101 ? 109.178 138.268 114.652 1.00 47.02  ? 47  ILE E CG1 1 
ATOM   11419 C CG2 . ILE E 1 101 ? 111.039 137.958 116.300 1.00 51.99  ? 47  ILE E CG2 1 
ATOM   11420 C CD1 . ILE E 1 101 ? 108.758 139.556 115.319 1.00 46.34  ? 47  ILE E CD1 1 
ATOM   11421 N N   . ASP E 1 102 ? 112.334 134.708 115.259 1.00 62.33  ? 48  ASP E N   1 
ATOM   11422 C CA  . ASP E 1 102 ? 113.072 133.643 115.933 1.00 64.48  ? 48  ASP E CA  1 
ATOM   11423 C C   . ASP E 1 102 ? 113.448 134.037 117.357 1.00 67.51  ? 48  ASP E C   1 
ATOM   11424 O O   . ASP E 1 102 ? 113.170 133.299 118.309 1.00 74.91  ? 48  ASP E O   1 
ATOM   11425 C CB  . ASP E 1 102 ? 114.318 133.278 115.125 1.00 66.81  ? 48  ASP E CB  1 
ATOM   11426 C CG  . ASP E 1 102 ? 113.988 132.824 113.717 1.00 71.06  ? 48  ASP E CG  1 
ATOM   11427 O OD1 . ASP E 1 102 ? 112.829 133.005 113.288 1.00 62.65  ? 48  ASP E OD1 1 
ATOM   11428 O OD2 . ASP E 1 102 ? 114.884 132.281 113.038 1.00 78.34  ? 48  ASP E OD2 1 
ATOM   11429 N N   . MET E 1 103 ? 114.076 135.198 117.524 1.00 65.74  ? 49  MET E N   1 
ATOM   11430 C CA  . MET E 1 103 ? 114.499 135.636 118.846 1.00 65.58  ? 49  MET E CA  1 
ATOM   11431 C C   . MET E 1 103 ? 114.764 137.133 118.821 1.00 66.56  ? 49  MET E C   1 
ATOM   11432 O O   . MET E 1 103 ? 115.249 137.667 117.822 1.00 68.89  ? 49  MET E O   1 
ATOM   11433 C CB  . MET E 1 103 ? 115.754 134.887 119.309 1.00 67.79  ? 49  MET E CB  1 
ATOM   11434 C CG  . MET E 1 103 ? 116.932 134.989 118.356 1.00 73.71  ? 49  MET E CG  1 
ATOM   11435 S SD  . MET E 1 103 ? 118.433 134.253 119.035 1.00 113.23 ? 49  MET E SD  1 
ATOM   11436 C CE  . MET E 1 103 ? 117.859 132.601 119.423 1.00 91.18  ? 49  MET E CE  1 
ATOM   11437 N N   . VAL E 1 104 ? 114.440 137.798 119.925 1.00 66.51  ? 50  VAL E N   1 
ATOM   11438 C CA  . VAL E 1 104 ? 114.734 139.211 120.121 1.00 59.35  ? 50  VAL E CA  1 
ATOM   11439 C C   . VAL E 1 104 ? 115.826 139.294 121.178 1.00 64.14  ? 50  VAL E C   1 
ATOM   11440 O O   . VAL E 1 104 ? 115.595 138.968 122.349 1.00 70.28  ? 50  VAL E O   1 
ATOM   11441 C CB  . VAL E 1 104 ? 113.487 140.001 120.538 1.00 56.57  ? 50  VAL E CB  1 
ATOM   11442 C CG1 . VAL E 1 104 ? 113.815 141.471 120.675 1.00 64.13  ? 50  VAL E CG1 1 
ATOM   11443 C CG2 . VAL E 1 104 ? 112.372 139.794 119.530 1.00 59.99  ? 50  VAL E CG2 1 
ATOM   11444 N N   . SER E 1 105 ? 117.014 139.733 120.773 1.00 63.16  ? 51  SER E N   1 
ATOM   11445 C CA  . SER E 1 105 ? 118.197 139.716 121.625 1.00 63.58  ? 51  SER E CA  1 
ATOM   11446 C C   . SER E 1 105 ? 118.492 141.123 122.121 1.00 67.04  ? 51  SER E C   1 
ATOM   11447 O O   . SER E 1 105 ? 118.795 142.015 121.322 1.00 70.13  ? 51  SER E O   1 
ATOM   11448 C CB  . SER E 1 105 ? 119.402 139.156 120.870 1.00 64.39  ? 51  SER E CB  1 
ATOM   11449 O OG  . SER E 1 105 ? 120.572 139.214 121.667 1.00 71.60  ? 51  SER E OG  1 
ATOM   11450 N N   . GLU E 1 106 ? 118.406 141.318 123.438 1.00 70.68  ? 52  GLU E N   1 
ATOM   11451 C CA  . GLU E 1 106 ? 118.801 142.593 124.024 1.00 70.86  ? 52  GLU E CA  1 
ATOM   11452 C C   . GLU E 1 106 ? 120.314 142.734 124.117 1.00 71.57  ? 52  GLU E C   1 
ATOM   11453 O O   . GLU E 1 106 ? 120.829 143.857 124.088 1.00 72.01  ? 52  GLU E O   1 
ATOM   11454 C CB  . GLU E 1 106 ? 118.179 142.757 125.413 1.00 74.27  ? 52  GLU E CB  1 
ATOM   11455 C CG  . GLU E 1 106 ? 116.657 142.814 125.430 1.00 74.72  ? 52  GLU E CG  1 
ATOM   11456 C CD  . GLU E 1 106 ? 116.015 141.440 125.484 1.00 82.63  ? 52  GLU E CD  1 
ATOM   11457 O OE1 . GLU E 1 106 ? 116.715 140.437 125.232 1.00 82.38  ? 52  GLU E OE1 1 
ATOM   11458 O OE2 . GLU E 1 106 ? 114.806 141.361 125.787 1.00 83.90  ? 52  GLU E OE2 1 
ATOM   11459 N N   . VAL E 1 107 ? 121.036 141.618 124.236 1.00 73.55  ? 53  VAL E N   1 
ATOM   11460 C CA  . VAL E 1 107 ? 122.490 141.681 124.351 1.00 76.29  ? 53  VAL E CA  1 
ATOM   11461 C C   . VAL E 1 107 ? 123.105 142.218 123.065 1.00 73.68  ? 53  VAL E C   1 
ATOM   11462 O O   . VAL E 1 107 ? 123.973 143.097 123.091 1.00 76.94  ? 53  VAL E O   1 
ATOM   11463 C CB  . VAL E 1 107 ? 123.057 140.297 124.713 1.00 73.24  ? 53  VAL E CB  1 
ATOM   11464 C CG1 . VAL E 1 107 ? 124.563 140.372 124.891 1.00 71.42  ? 53  VAL E CG1 1 
ATOM   11465 C CG2 . VAL E 1 107 ? 122.394 139.769 125.972 1.00 80.87  ? 53  VAL E CG2 1 
ATOM   11466 N N   . ASN E 1 108 ? 122.664 141.698 121.922 1.00 70.65  ? 54  ASN E N   1 
ATOM   11467 C CA  . ASN E 1 108 ? 123.161 142.148 120.630 1.00 71.08  ? 54  ASN E CA  1 
ATOM   11468 C C   . ASN E 1 108 ? 122.316 143.258 120.020 1.00 73.08  ? 54  ASN E C   1 
ATOM   11469 O O   . ASN E 1 108 ? 122.709 143.813 118.988 1.00 69.68  ? 54  ASN E O   1 
ATOM   11470 C CB  . ASN E 1 108 ? 123.231 140.969 119.655 1.00 67.77  ? 54  ASN E CB  1 
ATOM   11471 C CG  . ASN E 1 108 ? 123.925 139.762 120.251 1.00 70.10  ? 54  ASN E CG  1 
ATOM   11472 O OD1 . ASN E 1 108 ? 124.838 139.895 121.066 1.00 74.49  ? 54  ASN E OD1 1 
ATOM   11473 N ND2 . ASN E 1 108 ? 123.492 138.574 119.849 1.00 71.62  ? 54  ASN E ND2 1 
ATOM   11474 N N   . MET E 1 109 ? 121.182 143.594 120.634 1.00 72.90  ? 55  MET E N   1 
ATOM   11475 C CA  . MET E 1 109 ? 120.264 144.617 120.136 1.00 67.48  ? 55  MET E CA  1 
ATOM   11476 C C   . MET E 1 109 ? 119.869 144.340 118.685 1.00 66.15  ? 55  MET E C   1 
ATOM   11477 O O   . MET E 1 109 ? 120.110 145.137 117.777 1.00 66.58  ? 55  MET E O   1 
ATOM   11478 C CB  . MET E 1 109 ? 120.865 146.016 120.289 1.00 69.51  ? 55  MET E CB  1 
ATOM   11479 C CG  . MET E 1 109 ? 121.041 146.457 121.732 1.00 71.36  ? 55  MET E CG  1 
ATOM   11480 S SD  . MET E 1 109 ? 121.511 148.191 121.868 1.00 104.27 ? 55  MET E SD  1 
ATOM   11481 C CE  . MET E 1 109 ? 121.517 148.401 123.646 1.00 80.87  ? 55  MET E CE  1 
ATOM   11482 N N   . ASP E 1 110 ? 119.251 143.180 118.483 1.00 64.92  ? 56  ASP E N   1 
ATOM   11483 C CA  . ASP E 1 110 ? 118.800 142.768 117.161 1.00 58.73  ? 56  ASP E CA  1 
ATOM   11484 C C   . ASP E 1 110 ? 117.715 141.714 117.322 1.00 58.90  ? 56  ASP E C   1 
ATOM   11485 O O   . ASP E 1 110 ? 117.517 141.156 118.404 1.00 67.34  ? 56  ASP E O   1 
ATOM   11486 C CB  . ASP E 1 110 ? 119.961 142.242 116.312 1.00 59.18  ? 56  ASP E CB  1 
ATOM   11487 C CG  . ASP E 1 110 ? 120.722 141.119 116.991 1.00 69.47  ? 56  ASP E CG  1 
ATOM   11488 O OD1 . ASP E 1 110 ? 120.384 140.770 118.141 1.00 74.69  ? 56  ASP E OD1 1 
ATOM   11489 O OD2 . ASP E 1 110 ? 121.665 140.582 116.374 1.00 75.64  ? 56  ASP E OD2 1 
ATOM   11490 N N   . TYR E 1 111 ? 117.008 141.452 116.227 1.00 54.89  ? 57  TYR E N   1 
ATOM   11491 C CA  . TYR E 1 111 ? 115.970 140.433 116.214 1.00 55.02  ? 57  TYR E CA  1 
ATOM   11492 C C   . TYR E 1 111 ? 116.015 139.692 114.887 1.00 57.07  ? 57  TYR E C   1 
ATOM   11493 O O   . TYR E 1 111 ? 116.281 140.292 113.843 1.00 60.80  ? 57  TYR E O   1 
ATOM   11494 C CB  . TYR E 1 111 ? 114.580 141.040 116.442 1.00 46.53  ? 57  TYR E CB  1 
ATOM   11495 C CG  . TYR E 1 111 ? 114.102 141.955 115.337 1.00 46.82  ? 57  TYR E CG  1 
ATOM   11496 C CD1 . TYR E 1 111 ? 114.477 143.289 115.302 1.00 53.31  ? 57  TYR E CD1 1 
ATOM   11497 C CD2 . TYR E 1 111 ? 113.262 141.488 114.337 1.00 45.74  ? 57  TYR E CD2 1 
ATOM   11498 C CE1 . TYR E 1 111 ? 114.039 144.127 114.299 1.00 51.73  ? 57  TYR E CE1 1 
ATOM   11499 C CE2 . TYR E 1 111 ? 112.820 142.319 113.330 1.00 44.49  ? 57  TYR E CE2 1 
ATOM   11500 C CZ  . TYR E 1 111 ? 113.211 143.638 113.317 1.00 49.22  ? 57  TYR E CZ  1 
ATOM   11501 O OH  . TYR E 1 111 ? 112.772 144.471 112.316 1.00 57.51  ? 57  TYR E OH  1 
ATOM   11502 N N   . THR E 1 112 ? 115.737 138.394 114.932 1.00 53.00  ? 58  THR E N   1 
ATOM   11503 C CA  . THR E 1 112 ? 115.759 137.546 113.748 1.00 49.55  ? 58  THR E CA  1 
ATOM   11504 C C   . THR E 1 112 ? 114.338 137.353 113.240 1.00 51.82  ? 58  THR E C   1 
ATOM   11505 O O   . THR E 1 112 ? 113.440 136.998 114.009 1.00 55.59  ? 58  THR E O   1 
ATOM   11506 C CB  . THR E 1 112 ? 116.401 136.193 114.053 1.00 53.41  ? 58  THR E CB  1 
ATOM   11507 O OG1 . THR E 1 112 ? 117.708 136.398 114.599 1.00 61.64  ? 58  THR E OG1 1 
ATOM   11508 C CG2 . THR E 1 112 ? 116.520 135.367 112.785 1.00 58.16  ? 58  THR E CG2 1 
ATOM   11509 N N   . LEU E 1 113 ? 114.142 137.583 111.945 1.00 48.06  ? 59  LEU E N   1 
ATOM   11510 C CA  . LEU E 1 113 ? 112.824 137.565 111.329 1.00 43.80  ? 59  LEU E CA  1 
ATOM   11511 C C   . LEU E 1 113 ? 112.857 136.694 110.084 1.00 48.70  ? 59  LEU E C   1 
ATOM   11512 O O   . LEU E 1 113 ? 113.729 136.868 109.227 1.00 53.30  ? 59  LEU E O   1 
ATOM   11513 C CB  . LEU E 1 113 ? 112.381 138.984 110.967 1.00 38.86  ? 59  LEU E CB  1 
ATOM   11514 C CG  . LEU E 1 113 ? 111.067 139.117 110.204 1.00 44.64  ? 59  LEU E CG  1 
ATOM   11515 C CD1 . LEU E 1 113 ? 109.906 138.861 111.136 1.00 48.54  ? 59  LEU E CD1 1 
ATOM   11516 C CD2 . LEU E 1 113 ? 110.954 140.488 109.564 1.00 45.69  ? 59  LEU E CD2 1 
ATOM   11517 N N   . THR E 1 114 ? 111.908 135.769 109.980 1.00 45.77  ? 60  THR E N   1 
ATOM   11518 C CA  . THR E 1 114 ? 111.731 134.945 108.791 1.00 41.17  ? 60  THR E CA  1 
ATOM   11519 C C   . THR E 1 114 ? 110.421 135.328 108.121 1.00 42.61  ? 60  THR E C   1 
ATOM   11520 O O   . THR E 1 114 ? 109.381 135.409 108.782 1.00 49.40  ? 60  THR E O   1 
ATOM   11521 C CB  . THR E 1 114 ? 111.732 133.455 109.136 1.00 47.93  ? 60  THR E CB  1 
ATOM   11522 O OG1 . THR E 1 114 ? 112.957 133.115 109.794 1.00 55.55  ? 60  THR E OG1 1 
ATOM   11523 C CG2 . THR E 1 114 ? 111.597 132.621 107.872 1.00 40.65  ? 60  THR E CG2 1 
ATOM   11524 N N   . MET E 1 115 ? 110.468 135.556 106.813 1.00 38.56  ? 61  MET E N   1 
ATOM   11525 C CA  . MET E 1 115 ? 109.307 136.104 106.134 1.00 35.31  ? 61  MET E CA  1 
ATOM   11526 C C   . MET E 1 115 ? 109.265 135.658 104.683 1.00 35.88  ? 61  MET E C   1 
ATOM   11527 O O   . MET E 1 115 ? 110.268 135.235 104.101 1.00 40.05  ? 61  MET E O   1 
ATOM   11528 C CB  . MET E 1 115 ? 109.300 137.633 106.201 1.00 39.07  ? 61  MET E CB  1 
ATOM   11529 C CG  . MET E 1 115 ? 110.559 138.263 105.650 1.00 37.62  ? 61  MET E CG  1 
ATOM   11530 S SD  . MET E 1 115 ? 110.552 140.056 105.762 1.00 50.86  ? 61  MET E SD  1 
ATOM   11531 C CE  . MET E 1 115 ? 112.275 140.394 105.444 1.00 44.37  ? 61  MET E CE  1 
ATOM   11532 N N   . TYR E 1 116 ? 108.068 135.757 104.116 1.00 35.28  ? 62  TYR E N   1 
ATOM   11533 C CA  . TYR E 1 116 ? 107.832 135.646 102.684 1.00 36.35  ? 62  TYR E CA  1 
ATOM   11534 C C   . TYR E 1 116 ? 107.689 137.065 102.152 1.00 40.35  ? 62  TYR E C   1 
ATOM   11535 O O   . TYR E 1 116 ? 106.673 137.724 102.392 1.00 51.51  ? 62  TYR E O   1 
ATOM   11536 C CB  . TYR E 1 116 ? 106.575 134.831 102.393 1.00 43.93  ? 62  TYR E CB  1 
ATOM   11537 C CG  . TYR E 1 116 ? 106.612 133.405 102.884 1.00 47.01  ? 62  TYR E CG  1 
ATOM   11538 C CD1 . TYR E 1 116 ? 106.510 133.109 104.236 1.00 50.47  ? 62  TYR E CD1 1 
ATOM   11539 C CD2 . TYR E 1 116 ? 106.724 132.351 101.991 1.00 43.61  ? 62  TYR E CD2 1 
ATOM   11540 C CE1 . TYR E 1 116 ? 106.537 131.807 104.684 1.00 55.31  ? 62  TYR E CE1 1 
ATOM   11541 C CE2 . TYR E 1 116 ? 106.750 131.046 102.431 1.00 46.75  ? 62  TYR E CE2 1 
ATOM   11542 C CZ  . TYR E 1 116 ? 106.656 130.780 103.777 1.00 56.76  ? 62  TYR E CZ  1 
ATOM   11543 O OH  . TYR E 1 116 ? 106.681 129.479 104.215 1.00 65.48  ? 62  TYR E OH  1 
ATOM   11544 N N   . PHE E 1 117 ? 108.714 137.536 101.456 1.00 32.90  ? 63  PHE E N   1 
ATOM   11545 C CA  . PHE E 1 117 ? 108.770 138.892 100.933 1.00 31.85  ? 63  PHE E CA  1 
ATOM   11546 C C   . PHE E 1 117 ? 108.438 138.844 99.448  1.00 34.25  ? 63  PHE E C   1 
ATOM   11547 O O   . PHE E 1 117 ? 109.178 138.238 98.667  1.00 39.39  ? 63  PHE E O   1 
ATOM   11548 C CB  . PHE E 1 117 ? 110.159 139.480 101.181 1.00 31.56  ? 63  PHE E CB  1 
ATOM   11549 C CG  . PHE E 1 117 ? 110.376 140.832 100.577 1.00 29.81  ? 63  PHE E CG  1 
ATOM   11550 C CD1 . PHE E 1 117 ? 109.770 141.952 101.112 1.00 37.14  ? 63  PHE E CD1 1 
ATOM   11551 C CD2 . PHE E 1 117 ? 111.222 140.986 99.495  1.00 34.60  ? 63  PHE E CD2 1 
ATOM   11552 C CE1 . PHE E 1 117 ? 109.984 143.196 100.564 1.00 41.44  ? 63  PHE E CE1 1 
ATOM   11553 C CE2 . PHE E 1 117 ? 111.442 142.228 98.945  1.00 40.09  ? 63  PHE E CE2 1 
ATOM   11554 C CZ  . PHE E 1 117 ? 110.820 143.334 99.478  1.00 41.14  ? 63  PHE E CZ  1 
ATOM   11555 N N   . GLN E 1 118 ? 107.318 139.451 99.060  1.00 33.23  ? 64  GLN E N   1 
ATOM   11556 C CA  . GLN E 1 118 ? 106.853 139.411 97.682  1.00 34.14  ? 64  GLN E CA  1 
ATOM   11557 C C   . GLN E 1 118 ? 106.847 140.816 97.105  1.00 33.33  ? 64  GLN E C   1 
ATOM   11558 O O   . GLN E 1 118 ? 106.345 141.751 97.737  1.00 41.32  ? 64  GLN E O   1 
ATOM   11559 C CB  . GLN E 1 118 ? 105.454 138.804 97.584  1.00 38.50  ? 64  GLN E CB  1 
ATOM   11560 C CG  . GLN E 1 118 ? 105.349 137.385 98.098  1.00 45.17  ? 64  GLN E CG  1 
ATOM   11561 C CD  . GLN E 1 118 ? 103.947 136.834 97.969  1.00 58.90  ? 64  GLN E CD  1 
ATOM   11562 O OE1 . GLN E 1 118 ? 103.013 137.560 97.629  1.00 61.29  ? 64  GLN E OE1 1 
ATOM   11563 N NE2 . GLN E 1 118 ? 103.789 135.544 98.237  1.00 63.91  ? 64  GLN E NE2 1 
ATOM   11564 N N   . GLN E 1 119 ? 107.406 140.952 95.908  1.00 31.72  ? 65  GLN E N   1 
ATOM   11565 C CA  . GLN E 1 119 ? 107.389 142.186 95.144  1.00 31.85  ? 65  GLN E CA  1 
ATOM   11566 C C   . GLN E 1 119 ? 106.520 141.992 93.910  1.00 33.23  ? 65  GLN E C   1 
ATOM   11567 O O   . GLN E 1 119 ? 106.411 140.889 93.371  1.00 39.54  ? 65  GLN E O   1 
ATOM   11568 C CB  . GLN E 1 119 ? 108.803 142.603 94.740  1.00 33.93  ? 65  GLN E CB  1 
ATOM   11569 C CG  . GLN E 1 119 ? 109.783 142.599 95.895  1.00 35.39  ? 65  GLN E CG  1 
ATOM   11570 C CD  . GLN E 1 119 ? 111.178 143.009 95.482  1.00 40.25  ? 65  GLN E CD  1 
ATOM   11571 O OE1 . GLN E 1 119 ? 111.443 144.185 95.236  1.00 47.96  ? 65  GLN E OE1 1 
ATOM   11572 N NE2 . GLN E 1 119 ? 112.080 142.040 95.406  1.00 36.36  ? 65  GLN E NE2 1 
ATOM   11573 N N   . TYR E 1 120 ? 105.890 143.075 93.473  1.00 33.89  ? 66  TYR E N   1 
ATOM   11574 C CA  . TYR E 1 120 ? 104.849 143.000 92.454  1.00 36.63  ? 66  TYR E CA  1 
ATOM   11575 C C   . TYR E 1 120 ? 104.978 144.247 91.595  1.00 40.63  ? 66  TYR E C   1 
ATOM   11576 O O   . TYR E 1 120 ? 104.744 145.357 92.083  1.00 48.11  ? 66  TYR E O   1 
ATOM   11577 C CB  . TYR E 1 120 ? 103.476 142.905 93.119  1.00 45.92  ? 66  TYR E CB  1 
ATOM   11578 C CG  . TYR E 1 120 ? 102.275 142.920 92.204  1.00 52.76  ? 66  TYR E CG  1 
ATOM   11579 C CD1 . TYR E 1 120 ? 101.706 144.117 91.792  1.00 55.96  ? 66  TYR E CD1 1 
ATOM   11580 C CD2 . TYR E 1 120 ? 101.680 141.736 91.791  1.00 54.26  ? 66  TYR E CD2 1 
ATOM   11581 C CE1 . TYR E 1 120 ? 100.598 144.136 90.971  1.00 55.38  ? 66  TYR E CE1 1 
ATOM   11582 C CE2 . TYR E 1 120 ? 100.570 141.745 90.972  1.00 62.33  ? 66  TYR E CE2 1 
ATOM   11583 C CZ  . TYR E 1 120 ? 100.032 142.948 90.567  1.00 63.34  ? 66  TYR E CZ  1 
ATOM   11584 O OH  . TYR E 1 120 ? 98.928  142.961 89.748  1.00 74.34  ? 66  TYR E OH  1 
ATOM   11585 N N   . TRP E 1 121 ? 105.368 144.079 90.334  1.00 38.06  ? 67  TRP E N   1 
ATOM   11586 C CA  . TRP E 1 121 ? 105.557 145.241 89.469  1.00 40.68  ? 67  TRP E CA  1 
ATOM   11587 C C   . TRP E 1 121 ? 105.069 144.889 88.071  1.00 45.72  ? 67  TRP E C   1 
ATOM   11588 O O   . TRP E 1 121 ? 104.502 143.820 87.845  1.00 52.79  ? 67  TRP E O   1 
ATOM   11589 C CB  . TRP E 1 121 ? 107.019 145.710 89.487  1.00 40.44  ? 67  TRP E CB  1 
ATOM   11590 C CG  . TRP E 1 121 ? 107.972 144.802 88.788  1.00 39.36  ? 67  TRP E CG  1 
ATOM   11591 C CD1 . TRP E 1 121 ? 108.348 144.861 87.480  1.00 38.79  ? 67  TRP E CD1 1 
ATOM   11592 C CD2 . TRP E 1 121 ? 108.690 143.705 89.362  1.00 39.55  ? 67  TRP E CD2 1 
ATOM   11593 N NE1 . TRP E 1 121 ? 109.249 143.865 87.200  1.00 38.57  ? 67  TRP E NE1 1 
ATOM   11594 C CE2 . TRP E 1 121 ? 109.476 143.140 88.340  1.00 39.89  ? 67  TRP E CE2 1 
ATOM   11595 C CE3 . TRP E 1 121 ? 108.741 143.142 90.640  1.00 36.96  ? 67  TRP E CE3 1 
ATOM   11596 C CZ2 . TRP E 1 121 ? 110.302 142.042 88.555  1.00 39.04  ? 67  TRP E CZ2 1 
ATOM   11597 C CZ3 . TRP E 1 121 ? 109.561 142.053 90.851  1.00 35.09  ? 67  TRP E CZ3 1 
ATOM   11598 C CH2 . TRP E 1 121 ? 110.332 141.514 89.815  1.00 34.79  ? 67  TRP E CH2 1 
ATOM   11599 N N   . ARG E 1 122 ? 105.282 145.796 87.123  1.00 46.51  ? 68  ARG E N   1 
ATOM   11600 C CA  . ARG E 1 122 ? 104.813 145.610 85.757  1.00 52.70  ? 68  ARG E CA  1 
ATOM   11601 C C   . ARG E 1 122 ? 105.954 145.867 84.788  1.00 55.12  ? 68  ARG E C   1 
ATOM   11602 O O   . ARG E 1 122 ? 106.612 146.909 84.863  1.00 58.51  ? 68  ARG E O   1 
ATOM   11603 C CB  . ARG E 1 122 ? 103.634 146.537 85.444  1.00 53.25  ? 68  ARG E CB  1 
ATOM   11604 C CG  . ARG E 1 122 ? 103.026 146.319 84.070  1.00 58.87  ? 68  ARG E CG  1 
ATOM   11605 C CD  . ARG E 1 122 ? 101.972 147.367 83.762  1.00 74.08  ? 68  ARG E CD  1 
ATOM   11606 N NE  . ARG E 1 122 ? 101.398 147.190 82.434  1.00 90.92  ? 68  ARG E NE  1 
ATOM   11607 C CZ  . ARG E 1 122 ? 100.549 148.035 81.865  1.00 91.38  ? 68  ARG E CZ  1 
ATOM   11608 N NH1 . ARG E 1 122 ? 100.155 149.138 82.480  1.00 89.79  ? 68  ARG E NH1 1 
ATOM   11609 N NH2 . ARG E 1 122 ? 100.086 147.768 80.647  1.00 87.11  ? 68  ARG E NH2 1 
ATOM   11610 N N   . ASP E 1 123 ? 106.185 144.919 83.884  1.00 54.73  ? 69  ASP E N   1 
ATOM   11611 C CA  . ASP E 1 123 ? 107.183 145.057 82.828  1.00 52.96  ? 69  ASP E CA  1 
ATOM   11612 C C   . ASP E 1 123 ? 106.513 144.707 81.508  1.00 58.46  ? 69  ASP E C   1 
ATOM   11613 O O   . ASP E 1 123 ? 106.128 143.554 81.291  1.00 62.26  ? 69  ASP E O   1 
ATOM   11614 C CB  . ASP E 1 123 ? 108.393 144.158 83.085  1.00 50.17  ? 69  ASP E CB  1 
ATOM   11615 C CG  . ASP E 1 123 ? 109.555 144.467 82.162  1.00 58.51  ? 69  ASP E CG  1 
ATOM   11616 O OD1 . ASP E 1 123 ? 109.425 145.377 81.316  1.00 62.60  ? 69  ASP E OD1 1 
ATOM   11617 O OD2 . ASP E 1 123 ? 110.605 143.804 82.287  1.00 62.12  ? 69  ASP E OD2 1 
ATOM   11618 N N   . LYS E 1 124 ? 106.378 145.698 80.626  1.00 61.01  ? 70  LYS E N   1 
ATOM   11619 C CA  . LYS E 1 124 ? 105.709 145.471 79.351  1.00 62.33  ? 70  LYS E CA  1 
ATOM   11620 C C   . LYS E 1 124 ? 106.494 144.536 78.442  1.00 59.75  ? 70  LYS E C   1 
ATOM   11621 O O   . LYS E 1 124 ? 105.903 143.924 77.546  1.00 60.65  ? 70  LYS E O   1 
ATOM   11622 C CB  . LYS E 1 124 ? 105.462 146.804 78.645  1.00 63.78  ? 70  LYS E CB  1 
ATOM   11623 C CG  . LYS E 1 124 ? 104.564 147.748 79.422  1.00 72.03  ? 70  LYS E CG  1 
ATOM   11624 C CD  . LYS E 1 124 ? 104.382 149.061 78.688  1.00 79.92  ? 70  LYS E CD  1 
ATOM   11625 C CE  . LYS E 1 124 ? 103.491 150.011 79.467  1.00 89.90  ? 70  LYS E CE  1 
ATOM   11626 N NZ  . LYS E 1 124 ? 103.347 151.317 78.771  1.00 91.99  ? 70  LYS E NZ  1 
ATOM   11627 N N   . ARG E 1 125 ? 107.805 144.411 78.651  1.00 57.85  ? 71  ARG E N   1 
ATOM   11628 C CA  . ARG E 1 125 ? 108.602 143.487 77.854  1.00 57.95  ? 71  ARG E CA  1 
ATOM   11629 C C   . ARG E 1 125 ? 108.207 142.036 78.085  1.00 59.26  ? 71  ARG E C   1 
ATOM   11630 O O   . ARG E 1 125 ? 108.458 141.191 77.219  1.00 61.44  ? 71  ARG E O   1 
ATOM   11631 C CB  . ARG E 1 125 ? 110.085 143.674 78.162  1.00 55.76  ? 71  ARG E CB  1 
ATOM   11632 C CG  . ARG E 1 125 ? 110.598 145.071 77.890  1.00 54.95  ? 71  ARG E CG  1 
ATOM   11633 C CD  . ARG E 1 125 ? 112.025 145.226 78.368  1.00 57.34  ? 71  ARG E CD  1 
ATOM   11634 N NE  . ARG E 1 125 ? 112.128 145.073 79.814  1.00 57.95  ? 71  ARG E NE  1 
ATOM   11635 C CZ  . ARG E 1 125 ? 113.253 145.211 80.502  1.00 60.41  ? 71  ARG E CZ  1 
ATOM   11636 N NH1 . ARG E 1 125 ? 114.396 145.505 79.904  1.00 65.68  ? 71  ARG E NH1 1 
ATOM   11637 N NH2 . ARG E 1 125 ? 113.230 145.048 81.821  1.00 59.20  ? 71  ARG E NH2 1 
ATOM   11638 N N   . LEU E 1 126 ? 107.599 141.728 79.229  1.00 60.12  ? 72  LEU E N   1 
ATOM   11639 C CA  . LEU E 1 126 ? 107.198 140.371 79.567  1.00 63.34  ? 72  LEU E CA  1 
ATOM   11640 C C   . LEU E 1 126 ? 105.717 140.118 79.326  1.00 70.94  ? 72  LEU E C   1 
ATOM   11641 O O   . LEU E 1 126 ? 105.211 139.059 79.709  1.00 76.71  ? 72  LEU E O   1 
ATOM   11642 C CB  . LEU E 1 126 ? 107.551 140.070 81.023  1.00 52.92  ? 72  LEU E CB  1 
ATOM   11643 C CG  . LEU E 1 126 ? 109.021 140.289 81.382  1.00 52.03  ? 72  LEU E CG  1 
ATOM   11644 C CD1 . LEU E 1 126 ? 109.283 139.901 82.824  1.00 51.29  ? 72  LEU E CD1 1 
ATOM   11645 C CD2 . LEU E 1 126 ? 109.921 139.506 80.443  1.00 55.54  ? 72  LEU E CD2 1 
ATOM   11646 N N   . ALA E 1 127 ? 105.010 141.063 78.711  1.00 69.15  ? 73  ALA E N   1 
ATOM   11647 C CA  . ALA E 1 127 ? 103.609 140.848 78.383  1.00 66.55  ? 73  ALA E CA  1 
ATOM   11648 C C   . ALA E 1 127 ? 103.480 139.873 77.222  1.00 69.13  ? 73  ALA E C   1 
ATOM   11649 O O   . ALA E 1 127 ? 104.228 139.944 76.243  1.00 66.19  ? 73  ALA E O   1 
ATOM   11650 C CB  . ALA E 1 127 ? 102.933 142.174 78.037  1.00 63.32  ? 73  ALA E CB  1 
ATOM   11651 N N   . TYR E 1 128 ? 102.517 138.960 77.330  1.00 70.29  ? 74  TYR E N   1 
ATOM   11652 C CA  . TYR E 1 128 ? 102.325 137.922 76.330  1.00 70.34  ? 74  TYR E CA  1 
ATOM   11653 C C   . TYR E 1 128 ? 100.844 137.796 76.009  1.00 72.67  ? 74  TYR E C   1 
ATOM   11654 O O   . TYR E 1 128 ? 99.979  138.172 76.804  1.00 74.80  ? 74  TYR E O   1 
ATOM   11655 C CB  . TYR E 1 128 ? 102.889 136.572 76.800  1.00 70.24  ? 74  TYR E CB  1 
ATOM   11656 C CG  . TYR E 1 128 ? 102.300 136.073 78.100  1.00 68.54  ? 74  TYR E CG  1 
ATOM   11657 C CD1 . TYR E 1 128 ? 101.181 135.253 78.108  1.00 71.95  ? 74  TYR E CD1 1 
ATOM   11658 C CD2 . TYR E 1 128 ? 102.868 136.417 79.319  1.00 68.34  ? 74  TYR E CD2 1 
ATOM   11659 C CE1 . TYR E 1 128 ? 100.642 134.795 79.291  1.00 74.19  ? 74  TYR E CE1 1 
ATOM   11660 C CE2 . TYR E 1 128 ? 102.336 135.963 80.507  1.00 66.41  ? 74  TYR E CE2 1 
ATOM   11661 C CZ  . TYR E 1 128 ? 101.222 135.152 80.487  1.00 71.68  ? 74  TYR E CZ  1 
ATOM   11662 O OH  . TYR E 1 128 ? 100.686 134.695 81.666  1.00 76.95  ? 74  TYR E OH  1 
ATOM   11663 N N   . SER E 1 129 ? 100.563 137.265 74.824  1.00 73.98  ? 75  SER E N   1 
ATOM   11664 C CA  . SER E 1 129 ? 99.205  137.067 74.345  1.00 79.61  ? 75  SER E CA  1 
ATOM   11665 C C   . SER E 1 129 ? 99.004  135.610 73.948  1.00 85.50  ? 75  SER E C   1 
ATOM   11666 O O   . SER E 1 129 ? 99.955  134.832 73.836  1.00 85.16  ? 75  SER E O   1 
ATOM   11667 C CB  . SER E 1 129 ? 98.899  137.988 73.158  1.00 85.83  ? 75  SER E CB  1 
ATOM   11668 O OG  . SER E 1 129 ? 99.760  137.710 72.067  1.00 89.75  ? 75  SER E OG  1 
ATOM   11669 N N   . GLY E 1 130 ? 97.740  135.247 73.735  1.00 89.31  ? 76  GLY E N   1 
ATOM   11670 C CA  . GLY E 1 130 ? 97.384  133.905 73.332  1.00 93.26  ? 76  GLY E CA  1 
ATOM   11671 C C   . GLY E 1 130 ? 97.254  132.904 74.457  1.00 98.54  ? 76  GLY E C   1 
ATOM   11672 O O   . GLY E 1 130 ? 96.763  131.793 74.219  1.00 104.45 ? 76  GLY E O   1 
ATOM   11673 N N   . ILE E 1 131 ? 97.672  133.248 75.667  1.00 97.87  ? 77  ILE E N   1 
ATOM   11674 C CA  . ILE E 1 131 ? 97.600  132.360 76.817  1.00 91.15  ? 77  ILE E CA  1 
ATOM   11675 C C   . ILE E 1 131 ? 96.774  133.046 77.898  1.00 91.59  ? 77  ILE E C   1 
ATOM   11676 O O   . ILE E 1 131 ? 97.279  133.891 78.638  1.00 90.29  ? 77  ILE E O   1 
ATOM   11677 C CB  . ILE E 1 131 ? 99.001  131.995 77.339  1.00 85.41  ? 77  ILE E CB  1 
ATOM   11678 C CG1 . ILE E 1 131 ? 99.889  131.513 76.192  1.00 86.00  ? 77  ILE E CG1 1 
ATOM   11679 C CG2 . ILE E 1 131 ? 98.903  130.929 78.417  1.00 83.28  ? 77  ILE E CG2 1 
ATOM   11680 C CD1 . ILE E 1 131 ? 101.314 131.229 76.602  1.00 87.44  ? 77  ILE E CD1 1 
ATOM   11681 N N   . PRO E 1 132 ? 95.487  132.702 78.024  1.00 92.37  ? 78  PRO E N   1 
ATOM   11682 C CA  . PRO E 1 132 ? 94.624  133.291 79.057  1.00 96.31  ? 78  PRO E CA  1 
ATOM   11683 C C   . PRO E 1 132 ? 94.857  132.698 80.445  1.00 97.09  ? 78  PRO E C   1 
ATOM   11684 O O   . PRO E 1 132 ? 93.915  132.355 81.162  1.00 97.68  ? 78  PRO E O   1 
ATOM   11685 C CB  . PRO E 1 132 ? 93.218  132.981 78.536  1.00 91.11  ? 78  PRO E CB  1 
ATOM   11686 C CG  . PRO E 1 132 ? 93.386  131.703 77.796  1.00 90.03  ? 78  PRO E CG  1 
ATOM   11687 C CD  . PRO E 1 132 ? 94.753  131.758 77.164  1.00 86.84  ? 78  PRO E CD  1 
ATOM   11688 N N   . LEU E 1 133 ? 96.127  132.585 80.830  1.00 93.80  ? 79  LEU E N   1 
ATOM   11689 C CA  . LEU E 1 133 ? 96.511  131.974 82.092  1.00 84.13  ? 79  LEU E CA  1 
ATOM   11690 C C   . LEU E 1 133 ? 97.755  132.671 82.618  1.00 79.10  ? 79  LEU E C   1 
ATOM   11691 O O   . LEU E 1 133 ? 98.441  133.394 81.891  1.00 79.87  ? 79  LEU E O   1 
ATOM   11692 C CB  . LEU E 1 133 ? 96.775  130.471 81.939  1.00 84.91  ? 79  LEU E CB  1 
ATOM   11693 C CG  . LEU E 1 133 ? 95.609  129.557 81.560  1.00 88.06  ? 79  LEU E CG  1 
ATOM   11694 C CD1 . LEU E 1 133 ? 96.108  128.150 81.267  1.00 88.85  ? 79  LEU E CD1 1 
ATOM   11695 C CD2 . LEU E 1 133 ? 94.569  129.537 82.668  1.00 89.56  ? 79  LEU E CD2 1 
ATOM   11696 N N   . ASN E 1 134 ? 98.042  132.441 83.895  1.00 74.22  ? 80  ASN E N   1 
ATOM   11697 C CA  . ASN E 1 134 ? 99.226  132.983 84.546  1.00 68.21  ? 80  ASN E CA  1 
ATOM   11698 C C   . ASN E 1 134 ? 100.338 131.944 84.514  1.00 68.59  ? 80  ASN E C   1 
ATOM   11699 O O   . ASN E 1 134 ? 100.122 130.787 84.886  1.00 79.64  ? 80  ASN E O   1 
ATOM   11700 C CB  . ASN E 1 134 ? 98.921  133.384 85.988  1.00 70.20  ? 80  ASN E CB  1 
ATOM   11701 C CG  . ASN E 1 134 ? 97.966  134.552 86.075  1.00 78.72  ? 80  ASN E CG  1 
ATOM   11702 O OD1 . ASN E 1 134 ? 97.951  135.421 85.205  1.00 79.06  ? 80  ASN E OD1 1 
ATOM   11703 N ND2 . ASN E 1 134 ? 97.163  134.582 87.129  1.00 83.11  ? 80  ASN E ND2 1 
ATOM   11704 N N   . LEU E 1 135 ? 101.521 132.358 84.069  1.00 60.31  ? 81  LEU E N   1 
ATOM   11705 C CA  . LEU E 1 135 ? 102.655 131.452 83.924  1.00 53.52  ? 81  LEU E CA  1 
ATOM   11706 C C   . LEU E 1 135 ? 103.457 131.450 85.219  1.00 52.88  ? 81  LEU E C   1 
ATOM   11707 O O   . LEU E 1 135 ? 104.162 132.417 85.521  1.00 55.54  ? 81  LEU E O   1 
ATOM   11708 C CB  . LEU E 1 135 ? 103.531 131.866 82.746  1.00 52.59  ? 81  LEU E CB  1 
ATOM   11709 C CG  . LEU E 1 135 ? 102.835 132.111 81.407  1.00 62.85  ? 81  LEU E CG  1 
ATOM   11710 C CD1 . LEU E 1 135 ? 103.858 132.433 80.330  1.00 65.95  ? 81  LEU E CD1 1 
ATOM   11711 C CD2 . LEU E 1 135 ? 101.987 130.916 81.008  1.00 69.25  ? 81  LEU E CD2 1 
ATOM   11712 N N   . THR E 1 136 ? 103.348 130.371 85.987  1.00 51.12  ? 82  THR E N   1 
ATOM   11713 C CA  . THR E 1 136 ? 104.185 130.171 87.164  1.00 48.62  ? 82  THR E CA  1 
ATOM   11714 C C   . THR E 1 136 ? 105.455 129.461 86.714  1.00 50.69  ? 82  THR E C   1 
ATOM   11715 O O   . THR E 1 136 ? 105.432 128.260 86.427  1.00 54.98  ? 82  THR E O   1 
ATOM   11716 C CB  . THR E 1 136 ? 103.446 129.362 88.226  1.00 52.08  ? 82  THR E CB  1 
ATOM   11717 O OG1 . THR E 1 136 ? 102.292 130.087 88.665  1.00 56.23  ? 82  THR E OG1 1 
ATOM   11718 C CG2 . THR E 1 136 ? 104.355 129.098 89.410  1.00 58.94  ? 82  THR E CG2 1 
ATOM   11719 N N   . LEU E 1 137 ? 106.559 130.194 86.649  1.00 47.50  ? 83  LEU E N   1 
ATOM   11720 C CA  . LEU E 1 137 ? 107.774 129.670 86.047  1.00 46.67  ? 83  LEU E CA  1 
ATOM   11721 C C   . LEU E 1 137 ? 108.726 129.135 87.107  1.00 53.77  ? 83  LEU E C   1 
ATOM   11722 O O   . LEU E 1 137 ? 108.643 129.480 88.288  1.00 52.92  ? 83  LEU E O   1 
ATOM   11723 C CB  . LEU E 1 137 ? 108.480 130.747 85.219  1.00 42.26  ? 83  LEU E CB  1 
ATOM   11724 C CG  . LEU E 1 137 ? 107.720 131.319 84.023  1.00 44.38  ? 83  LEU E CG  1 
ATOM   11725 C CD1 . LEU E 1 137 ? 108.628 132.224 83.207  1.00 45.67  ? 83  LEU E CD1 1 
ATOM   11726 C CD2 . LEU E 1 137 ? 107.161 130.202 83.162  1.00 53.38  ? 83  LEU E CD2 1 
ATOM   11727 N N   . ASP E 1 138 ? 109.631 128.266 86.664  1.00 55.00  ? 84  ASP E N   1 
ATOM   11728 C CA  . ASP E 1 138 ? 110.717 127.816 87.519  1.00 55.94  ? 84  ASP E CA  1 
ATOM   11729 C C   . ASP E 1 138 ? 111.524 129.016 87.995  1.00 58.34  ? 84  ASP E C   1 
ATOM   11730 O O   . ASP E 1 138 ? 111.821 129.928 87.220  1.00 61.24  ? 84  ASP E O   1 
ATOM   11731 C CB  . ASP E 1 138 ? 111.613 126.836 86.762  1.00 59.01  ? 84  ASP E CB  1 
ATOM   11732 C CG  . ASP E 1 138 ? 112.682 126.224 87.640  1.00 66.76  ? 84  ASP E CG  1 
ATOM   11733 O OD1 . ASP E 1 138 ? 112.528 126.254 88.878  1.00 68.08  ? 84  ASP E OD1 1 
ATOM   11734 O OD2 . ASP E 1 138 ? 113.680 125.712 87.090  1.00 71.31  ? 84  ASP E OD2 1 
ATOM   11735 N N   . ASN E 1 139 ? 111.877 129.013 89.282  1.00 59.48  ? 85  ASN E N   1 
ATOM   11736 C CA  . ASN E 1 139 ? 112.517 130.179 89.882  1.00 54.49  ? 85  ASN E CA  1 
ATOM   11737 C C   . ASN E 1 139 ? 113.850 130.521 89.230  1.00 54.28  ? 85  ASN E C   1 
ATOM   11738 O O   . ASN E 1 139 ? 114.307 131.664 89.346  1.00 57.35  ? 85  ASN E O   1 
ATOM   11739 C CB  . ASN E 1 139 ? 112.714 129.955 91.381  1.00 52.14  ? 85  ASN E CB  1 
ATOM   11740 C CG  . ASN E 1 139 ? 113.524 128.714 91.683  1.00 55.34  ? 85  ASN E CG  1 
ATOM   11741 O OD1 . ASN E 1 139 ? 114.752 128.760 91.752  1.00 56.84  ? 85  ASN E OD1 1 
ATOM   11742 N ND2 . ASN E 1 139 ? 112.839 127.592 91.868  1.00 55.97  ? 85  ASN E ND2 1 
ATOM   11743 N N   . ARG E 1 140 ? 114.477 129.571 88.536  1.00 55.56  ? 86  ARG E N   1 
ATOM   11744 C CA  . ARG E 1 140 ? 115.746 129.853 87.880  1.00 62.09  ? 86  ARG E CA  1 
ATOM   11745 C C   . ARG E 1 140 ? 115.609 130.833 86.724  1.00 60.42  ? 86  ARG E C   1 
ATOM   11746 O O   . ARG E 1 140 ? 116.628 131.334 86.239  1.00 63.40  ? 86  ARG E O   1 
ATOM   11747 C CB  . ARG E 1 140 ? 116.384 128.552 87.395  1.00 63.89  ? 86  ARG E CB  1 
ATOM   11748 C CG  . ARG E 1 140 ? 117.002 127.736 88.517  1.00 67.28  ? 86  ARG E CG  1 
ATOM   11749 C CD  . ARG E 1 140 ? 117.437 126.366 88.042  1.00 65.21  ? 86  ARG E CD  1 
ATOM   11750 N NE  . ARG E 1 140 ? 116.297 125.541 87.664  1.00 63.91  ? 86  ARG E NE  1 
ATOM   11751 C CZ  . ARG E 1 140 ? 116.365 124.240 87.416  1.00 70.82  ? 86  ARG E CZ  1 
ATOM   11752 N NH1 . ARG E 1 140 ? 117.507 123.579 87.507  1.00 73.93  ? 86  ARG E NH1 1 
ATOM   11753 N NH2 . ARG E 1 140 ? 115.260 123.587 87.073  1.00 76.69  ? 86  ARG E NH2 1 
ATOM   11754 N N   . VAL E 1 141 ? 114.386 131.123 86.275  1.00 54.68  ? 87  VAL E N   1 
ATOM   11755 C CA  . VAL E 1 141 ? 114.198 132.174 85.284  1.00 52.69  ? 87  VAL E CA  1 
ATOM   11756 C C   . VAL E 1 141 ? 114.409 133.555 85.890  1.00 55.65  ? 87  VAL E C   1 
ATOM   11757 O O   . VAL E 1 141 ? 114.613 134.525 85.149  1.00 59.08  ? 87  VAL E O   1 
ATOM   11758 C CB  . VAL E 1 141 ? 112.806 132.079 84.637  1.00 44.78  ? 87  VAL E CB  1 
ATOM   11759 C CG1 . VAL E 1 141 ? 111.747 132.667 85.553  1.00 38.74  ? 87  VAL E CG1 1 
ATOM   11760 C CG2 . VAL E 1 141 ? 112.795 132.772 83.285  1.00 47.51  ? 87  VAL E CG2 1 
ATOM   11761 N N   . ALA E 1 142 ? 114.386 133.669 87.222  1.00 54.20  ? 88  ALA E N   1 
ATOM   11762 C CA  . ALA E 1 142 ? 114.604 134.958 87.868  1.00 51.77  ? 88  ALA E CA  1 
ATOM   11763 C C   . ALA E 1 142 ? 115.986 135.524 87.580  1.00 56.44  ? 88  ALA E C   1 
ATOM   11764 O O   . ALA E 1 142 ? 116.195 136.731 87.743  1.00 56.96  ? 88  ALA E O   1 
ATOM   11765 C CB  . ALA E 1 142 ? 114.402 134.832 89.377  1.00 48.60  ? 88  ALA E CB  1 
ATOM   11766 N N   . ASP E 1 143 ? 116.933 134.685 87.164  1.00 61.92  ? 89  ASP E N   1 
ATOM   11767 C CA  . ASP E 1 143 ? 118.258 135.161 86.797  1.00 64.50  ? 89  ASP E CA  1 
ATOM   11768 C C   . ASP E 1 143 ? 118.280 135.849 85.440  1.00 61.81  ? 89  ASP E C   1 
ATOM   11769 O O   . ASP E 1 143 ? 119.261 136.531 85.126  1.00 62.86  ? 89  ASP E O   1 
ATOM   11770 C CB  . ASP E 1 143 ? 119.252 133.997 86.795  1.00 68.87  ? 89  ASP E CB  1 
ATOM   11771 C CG  . ASP E 1 143 ? 119.224 133.206 88.087  1.00 74.18  ? 89  ASP E CG  1 
ATOM   11772 O OD1 . ASP E 1 143 ? 118.947 133.803 89.146  1.00 76.03  ? 89  ASP E OD1 1 
ATOM   11773 O OD2 . ASP E 1 143 ? 119.476 131.983 88.041  1.00 73.66  ? 89  ASP E OD2 1 
ATOM   11774 N N   . GLN E 1 144 ? 117.232 135.690 84.634  1.00 57.73  ? 90  GLN E N   1 
ATOM   11775 C CA  . GLN E 1 144 ? 117.177 136.286 83.309  1.00 56.74  ? 90  GLN E CA  1 
ATOM   11776 C C   . GLN E 1 144 ? 116.249 137.488 83.220  1.00 56.46  ? 90  GLN E C   1 
ATOM   11777 O O   . GLN E 1 144 ? 116.220 138.146 82.175  1.00 61.83  ? 90  GLN E O   1 
ATOM   11778 C CB  . GLN E 1 144 ? 116.752 135.233 82.276  1.00 58.76  ? 90  GLN E CB  1 
ATOM   11779 C CG  . GLN E 1 144 ? 117.734 134.080 82.152  1.00 63.08  ? 90  GLN E CG  1 
ATOM   11780 C CD  . GLN E 1 144 ? 117.053 132.729 82.175  1.00 72.30  ? 90  GLN E CD  1 
ATOM   11781 O OE1 . GLN E 1 144 ? 115.878 132.610 81.832  1.00 78.14  ? 90  GLN E OE1 1 
ATOM   11782 N NE2 . GLN E 1 144 ? 117.786 131.702 82.591  1.00 71.77  ? 90  GLN E NE2 1 
ATOM   11783 N N   . LEU E 1 145 ? 115.493 137.788 84.271  1.00 53.00  ? 91  LEU E N   1 
ATOM   11784 C CA  . LEU E 1 145 ? 114.625 138.951 84.297  1.00 49.51  ? 91  LEU E CA  1 
ATOM   11785 C C   . LEU E 1 145 ? 115.304 140.092 85.047  1.00 55.41  ? 91  LEU E C   1 
ATOM   11786 O O   . LEU E 1 145 ? 116.400 139.953 85.593  1.00 61.23  ? 91  LEU E O   1 
ATOM   11787 C CB  . LEU E 1 145 ? 113.281 138.606 84.939  1.00 47.39  ? 91  LEU E CB  1 
ATOM   11788 C CG  . LEU E 1 145 ? 112.461 137.485 84.304  1.00 47.65  ? 91  LEU E CG  1 
ATOM   11789 C CD1 . LEU E 1 145 ? 111.125 137.344 85.011  1.00 39.30  ? 91  LEU E CD1 1 
ATOM   11790 C CD2 . LEU E 1 145 ? 112.259 137.746 82.825  1.00 49.62  ? 91  LEU E CD2 1 
ATOM   11791 N N   . TRP E 1 146 ? 114.637 141.240 85.069  1.00 55.61  ? 92  TRP E N   1 
ATOM   11792 C CA  . TRP E 1 146 ? 115.048 142.371 85.886  1.00 52.39  ? 92  TRP E CA  1 
ATOM   11793 C C   . TRP E 1 146 ? 114.244 142.352 87.176  1.00 50.76  ? 92  TRP E C   1 
ATOM   11794 O O   . TRP E 1 146 ? 113.020 142.197 87.145  1.00 54.45  ? 92  TRP E O   1 
ATOM   11795 C CB  . TRP E 1 146 ? 114.835 143.694 85.150  1.00 47.93  ? 92  TRP E CB  1 
ATOM   11796 C CG  . TRP E 1 146 ? 115.146 144.903 85.982  1.00 45.60  ? 92  TRP E CG  1 
ATOM   11797 C CD1 . TRP E 1 146 ? 116.325 145.586 86.023  1.00 46.62  ? 92  TRP E CD1 1 
ATOM   11798 C CD2 . TRP E 1 146 ? 114.265 145.572 86.894  1.00 42.92  ? 92  TRP E CD2 1 
ATOM   11799 N NE1 . TRP E 1 146 ? 116.233 146.638 86.901  1.00 44.41  ? 92  TRP E NE1 1 
ATOM   11800 C CE2 . TRP E 1 146 ? 114.979 146.650 87.450  1.00 43.34  ? 92  TRP E CE2 1 
ATOM   11801 C CE3 . TRP E 1 146 ? 112.943 145.361 87.296  1.00 42.11  ? 92  TRP E CE3 1 
ATOM   11802 C CZ2 . TRP E 1 146 ? 114.415 147.515 88.383  1.00 44.80  ? 92  TRP E CZ2 1 
ATOM   11803 C CZ3 . TRP E 1 146 ? 112.386 146.221 88.220  1.00 38.85  ? 92  TRP E CZ3 1 
ATOM   11804 C CH2 . TRP E 1 146 ? 113.121 147.284 88.755  1.00 42.90  ? 92  TRP E CH2 1 
ATOM   11805 N N   . VAL E 1 147 ? 114.929 142.506 88.302  1.00 47.12  ? 93  VAL E N   1 
ATOM   11806 C CA  . VAL E 1 147 ? 114.260 142.536 89.598  1.00 43.63  ? 93  VAL E CA  1 
ATOM   11807 C C   . VAL E 1 147 ? 114.708 143.789 90.339  1.00 44.84  ? 93  VAL E C   1 
ATOM   11808 O O   . VAL E 1 147 ? 115.840 144.253 90.139  1.00 44.69  ? 93  VAL E O   1 
ATOM   11809 C CB  . VAL E 1 147 ? 114.557 141.267 90.411  1.00 45.42  ? 93  VAL E CB  1 
ATOM   11810 C CG1 . VAL E 1 147 ? 113.894 140.065 89.769  1.00 39.24  ? 93  VAL E CG1 1 
ATOM   11811 C CG2 . VAL E 1 147 ? 116.053 141.050 90.516  1.00 46.96  ? 93  VAL E CG2 1 
ATOM   11812 N N   . PRO E 1 148 ? 113.861 144.378 91.181  1.00 45.01  ? 94  PRO E N   1 
ATOM   11813 C CA  . PRO E 1 148 ? 114.284 145.560 91.934  1.00 43.09  ? 94  PRO E CA  1 
ATOM   11814 C C   . PRO E 1 148 ? 115.444 145.232 92.859  1.00 45.20  ? 94  PRO E C   1 
ATOM   11815 O O   . PRO E 1 148 ? 115.538 144.133 93.409  1.00 45.98  ? 94  PRO E O   1 
ATOM   11816 C CB  . PRO E 1 148 ? 113.030 145.947 92.725  1.00 41.67  ? 94  PRO E CB  1 
ATOM   11817 C CG  . PRO E 1 148 ? 111.901 145.326 91.977  1.00 41.23  ? 94  PRO E CG  1 
ATOM   11818 C CD  . PRO E 1 148 ? 112.447 144.051 91.418  1.00 42.30  ? 94  PRO E CD  1 
ATOM   11819 N N   . ASP E 1 149 ? 116.337 146.203 93.022  1.00 48.17  ? 95  ASP E N   1 
ATOM   11820 C CA  . ASP E 1 149 ? 117.468 146.064 93.938  1.00 48.42  ? 95  ASP E CA  1 
ATOM   11821 C C   . ASP E 1 149 ? 117.058 146.405 95.366  1.00 43.46  ? 95  ASP E C   1 
ATOM   11822 O O   . ASP E 1 149 ? 117.672 147.227 96.043  1.00 44.23  ? 95  ASP E O   1 
ATOM   11823 C CB  . ASP E 1 149 ? 118.626 146.937 93.474  1.00 48.10  ? 95  ASP E CB  1 
ATOM   11824 C CG  . ASP E 1 149 ? 118.224 148.383 93.284  1.00 56.69  ? 95  ASP E CG  1 
ATOM   11825 O OD1 . ASP E 1 149 ? 117.022 148.694 93.424  1.00 58.39  ? 95  ASP E OD1 1 
ATOM   11826 O OD2 . ASP E 1 149 ? 119.112 149.211 92.994  1.00 59.78  ? 95  ASP E OD2 1 
ATOM   11827 N N   . THR E 1 150 ? 115.995 145.755 95.825  1.00 40.64  ? 96  THR E N   1 
ATOM   11828 C CA  . THR E 1 150 ? 115.449 146.033 97.143  1.00 41.44  ? 96  THR E CA  1 
ATOM   11829 C C   . THR E 1 150 ? 116.330 145.424 98.223  1.00 42.65  ? 96  THR E C   1 
ATOM   11830 O O   . THR E 1 150 ? 116.676 144.241 98.165  1.00 50.77  ? 96  THR E O   1 
ATOM   11831 C CB  . THR E 1 150 ? 114.031 145.479 97.246  1.00 43.55  ? 96  THR E CB  1 
ATOM   11832 O OG1 . THR E 1 150 ? 113.140 146.303 96.486  1.00 48.19  ? 96  THR E OG1 1 
ATOM   11833 C CG2 . THR E 1 150 ? 113.579 145.437 98.688  1.00 40.31  ? 96  THR E CG2 1 
ATOM   11834 N N   . TYR E 1 151 ? 116.685 146.232 99.218  1.00 36.52  ? 97  TYR E N   1 
ATOM   11835 C CA  . TYR E 1 151 ? 117.468 145.756 100.343 1.00 35.65  ? 97  TYR E CA  1 
ATOM   11836 C C   . TYR E 1 151 ? 116.864 146.292 101.631 1.00 36.03  ? 97  TYR E C   1 
ATOM   11837 O O   . TYR E 1 151 ? 115.962 147.136 101.623 1.00 39.29  ? 97  TYR E O   1 
ATOM   11838 C CB  . TYR E 1 151 ? 118.941 146.159 100.215 1.00 36.77  ? 97  TYR E CB  1 
ATOM   11839 C CG  . TYR E 1 151 ? 119.235 147.584 100.609 1.00 36.19  ? 97  TYR E CG  1 
ATOM   11840 C CD1 . TYR E 1 151 ? 118.764 148.646 99.856  1.00 38.18  ? 97  TYR E CD1 1 
ATOM   11841 C CD2 . TYR E 1 151 ? 120.001 147.867 101.727 1.00 36.65  ? 97  TYR E CD2 1 
ATOM   11842 C CE1 . TYR E 1 151 ? 119.036 149.948 100.214 1.00 37.30  ? 97  TYR E CE1 1 
ATOM   11843 C CE2 . TYR E 1 151 ? 120.281 149.162 102.090 1.00 38.53  ? 97  TYR E CE2 1 
ATOM   11844 C CZ  . TYR E 1 151 ? 119.797 150.200 101.330 1.00 38.38  ? 97  TYR E CZ  1 
ATOM   11845 O OH  . TYR E 1 151 ? 120.075 151.496 101.690 1.00 46.35  ? 97  TYR E OH  1 
ATOM   11846 N N   . PHE E 1 152 ? 117.362 145.772 102.747 1.00 34.94  ? 98  PHE E N   1 
ATOM   11847 C CA  . PHE E 1 152 ? 116.903 146.154 104.075 1.00 36.50  ? 98  PHE E CA  1 
ATOM   11848 C C   . PHE E 1 152 ? 117.993 146.984 104.734 1.00 42.92  ? 98  PHE E C   1 
ATOM   11849 O O   . PHE E 1 152 ? 119.138 146.535 104.848 1.00 46.59  ? 98  PHE E O   1 
ATOM   11850 C CB  . PHE E 1 152 ? 116.555 144.921 104.906 1.00 37.20  ? 98  PHE E CB  1 
ATOM   11851 C CG  . PHE E 1 152 ? 115.551 144.023 104.247 1.00 37.08  ? 98  PHE E CG  1 
ATOM   11852 C CD1 . PHE E 1 152 ? 114.203 144.328 104.281 1.00 37.74  ? 98  PHE E CD1 1 
ATOM   11853 C CD2 . PHE E 1 152 ? 115.958 142.886 103.577 1.00 38.12  ? 98  PHE E CD2 1 
ATOM   11854 C CE1 . PHE E 1 152 ? 113.280 143.511 103.668 1.00 36.87  ? 98  PHE E CE1 1 
ATOM   11855 C CE2 . PHE E 1 152 ? 115.040 142.065 102.962 1.00 39.93  ? 98  PHE E CE2 1 
ATOM   11856 C CZ  . PHE E 1 152 ? 113.700 142.378 103.006 1.00 36.23  ? 98  PHE E CZ  1 
ATOM   11857 N N   . LEU E 1 153 ? 117.636 148.197 105.154 1.00 44.43  ? 99  LEU E N   1 
ATOM   11858 C CA  . LEU E 1 153 ? 118.646 149.162 105.568 1.00 42.74  ? 99  LEU E CA  1 
ATOM   11859 C C   . LEU E 1 153 ? 119.290 148.790 106.896 1.00 48.90  ? 99  LEU E C   1 
ATOM   11860 O O   . LEU E 1 153 ? 120.483 149.044 107.093 1.00 58.02  ? 99  LEU E O   1 
ATOM   11861 C CB  . LEU E 1 153 ? 118.023 150.555 105.642 1.00 46.27  ? 99  LEU E CB  1 
ATOM   11862 C CG  . LEU E 1 153 ? 118.981 151.732 105.803 1.00 54.44  ? 99  LEU E CG  1 
ATOM   11863 C CD1 . LEU E 1 153 ? 118.540 152.885 104.923 1.00 59.30  ? 99  LEU E CD1 1 
ATOM   11864 C CD2 . LEU E 1 153 ? 119.051 152.172 107.255 1.00 52.31  ? 99  LEU E CD2 1 
ATOM   11865 N N   . ASN E 1 154 ? 118.534 148.189 107.813 1.00 46.99  ? 100 ASN E N   1 
ATOM   11866 C CA  . ASN E 1 154 ? 119.019 147.937 109.163 1.00 46.73  ? 100 ASN E CA  1 
ATOM   11867 C C   . ASN E 1 154 ? 119.384 146.478 109.409 1.00 48.74  ? 100 ASN E C   1 
ATOM   11868 O O   . ASN E 1 154 ? 119.601 146.094 110.562 1.00 52.79  ? 100 ASN E O   1 
ATOM   11869 C CB  . ASN E 1 154 ? 117.984 148.398 110.191 1.00 48.42  ? 100 ASN E CB  1 
ATOM   11870 C CG  . ASN E 1 154 ? 116.689 147.617 110.109 1.00 49.50  ? 100 ASN E CG  1 
ATOM   11871 O OD1 . ASN E 1 154 ? 116.334 147.091 109.055 1.00 47.18  ? 100 ASN E OD1 1 
ATOM   11872 N ND2 . ASN E 1 154 ? 115.974 147.542 111.223 1.00 53.03  ? 100 ASN E ND2 1 
ATOM   11873 N N   . ASP E 1 155 ? 119.459 145.657 108.365 1.00 47.35  ? 101 ASP E N   1 
ATOM   11874 C CA  . ASP E 1 155 ? 119.826 144.264 108.562 1.00 49.74  ? 101 ASP E CA  1 
ATOM   11875 C C   . ASP E 1 155 ? 121.331 144.130 108.784 1.00 51.08  ? 101 ASP E C   1 
ATOM   11876 O O   . ASP E 1 155 ? 122.120 145.015 108.445 1.00 53.68  ? 101 ASP E O   1 
ATOM   11877 C CB  . ASP E 1 155 ? 119.387 143.410 107.372 1.00 49.48  ? 101 ASP E CB  1 
ATOM   11878 C CG  . ASP E 1 155 ? 120.277 143.588 106.158 1.00 53.70  ? 101 ASP E CG  1 
ATOM   11879 O OD1 . ASP E 1 155 ? 120.807 144.698 105.956 1.00 59.28  ? 101 ASP E OD1 1 
ATOM   11880 O OD2 . ASP E 1 155 ? 120.448 142.610 105.402 1.00 54.44  ? 101 ASP E OD2 1 
ATOM   11881 N N   . LYS E 1 156 ? 121.721 143.001 109.362 1.00 49.50  ? 102 LYS E N   1 
ATOM   11882 C CA  . LYS E 1 156 ? 123.115 142.699 109.650 1.00 46.73  ? 102 LYS E CA  1 
ATOM   11883 C C   . LYS E 1 156 ? 123.598 141.434 108.966 1.00 52.03  ? 102 LYS E C   1 
ATOM   11884 O O   . LYS E 1 156 ? 124.734 141.392 108.488 1.00 60.25  ? 102 LYS E O   1 
ATOM   11885 C CB  . LYS E 1 156 ? 123.314 142.567 111.166 1.00 46.50  ? 102 LYS E CB  1 
ATOM   11886 C CG  . LYS E 1 156 ? 122.804 143.757 111.958 1.00 48.74  ? 102 LYS E CG  1 
ATOM   11887 C CD  . LYS E 1 156 ? 122.712 143.439 113.438 1.00 50.13  ? 102 LYS E CD  1 
ATOM   11888 C CE  . LYS E 1 156 ? 124.064 143.061 114.011 1.00 53.32  ? 102 LYS E CE  1 
ATOM   11889 N NZ  . LYS E 1 156 ? 123.965 142.708 115.452 1.00 54.23  ? 102 LYS E NZ  1 
ATOM   11890 N N   . LYS E 1 157 ? 122.762 140.402 108.906 1.00 49.69  ? 103 LYS E N   1 
ATOM   11891 C CA  . LYS E 1 157 ? 123.117 139.156 108.235 1.00 51.35  ? 103 LYS E CA  1 
ATOM   11892 C C   . LYS E 1 157 ? 121.825 138.514 107.754 1.00 50.94  ? 103 LYS E C   1 
ATOM   11893 O O   . LYS E 1 157 ? 121.084 137.938 108.555 1.00 53.74  ? 103 LYS E O   1 
ATOM   11894 C CB  . LYS E 1 157 ? 123.884 138.223 109.166 1.00 55.94  ? 103 LYS E CB  1 
ATOM   11895 C CG  . LYS E 1 157 ? 125.309 137.949 108.724 1.00 58.34  ? 103 LYS E CG  1 
ATOM   11896 C CD  . LYS E 1 157 ? 125.345 137.444 107.293 1.00 56.57  ? 103 LYS E CD  1 
ATOM   11897 C CE  . LYS E 1 157 ? 126.769 137.179 106.836 1.00 60.94  ? 103 LYS E CE  1 
ATOM   11898 N NZ  . LYS E 1 157 ? 126.823 136.720 105.421 1.00 63.21  ? 103 LYS E NZ  1 
ATOM   11899 N N   . SER E 1 158 ? 121.560 138.612 106.455 1.00 47.81  ? 104 SER E N   1 
ATOM   11900 C CA  . SER E 1 158 ? 120.344 138.079 105.865 1.00 45.29  ? 104 SER E CA  1 
ATOM   11901 C C   . SER E 1 158 ? 120.698 137.174 104.695 1.00 44.73  ? 104 SER E C   1 
ATOM   11902 O O   . SER E 1 158 ? 121.715 137.370 104.024 1.00 50.47  ? 104 SER E O   1 
ATOM   11903 C CB  . SER E 1 158 ? 119.409 139.202 105.401 1.00 46.19  ? 104 SER E CB  1 
ATOM   11904 O OG  . SER E 1 158 ? 120.114 140.172 104.647 1.00 57.25  ? 104 SER E OG  1 
ATOM   11905 N N   . PHE E 1 159 ? 119.848 136.179 104.456 1.00 40.52  ? 105 PHE E N   1 
ATOM   11906 C CA  . PHE E 1 159 ? 120.085 135.213 103.396 1.00 38.84  ? 105 PHE E CA  1 
ATOM   11907 C C   . PHE E 1 159 ? 118.751 134.717 102.861 1.00 35.49  ? 105 PHE E C   1 
ATOM   11908 O O   . PHE E 1 159 ? 117.696 134.930 103.461 1.00 35.36  ? 105 PHE E O   1 
ATOM   11909 C CB  . PHE E 1 159 ? 120.941 134.039 103.886 1.00 40.07  ? 105 PHE E CB  1 
ATOM   11910 C CG  . PHE E 1 159 ? 120.277 133.196 104.938 1.00 38.84  ? 105 PHE E CG  1 
ATOM   11911 C CD1 . PHE E 1 159 ? 119.549 132.072 104.587 1.00 38.65  ? 105 PHE E CD1 1 
ATOM   11912 C CD2 . PHE E 1 159 ? 120.390 133.520 106.277 1.00 35.68  ? 105 PHE E CD2 1 
ATOM   11913 C CE1 . PHE E 1 159 ? 118.939 131.295 105.551 1.00 36.51  ? 105 PHE E CE1 1 
ATOM   11914 C CE2 . PHE E 1 159 ? 119.784 132.745 107.246 1.00 33.91  ? 105 PHE E CE2 1 
ATOM   11915 C CZ  . PHE E 1 159 ? 119.058 131.631 106.882 1.00 34.19  ? 105 PHE E CZ  1 
ATOM   11916 N N   . VAL E 1 160 ? 118.816 134.049 101.714 1.00 34.91  ? 106 VAL E N   1 
ATOM   11917 C CA  . VAL E 1 160 ? 117.658 133.428 101.082 1.00 36.02  ? 106 VAL E CA  1 
ATOM   11918 C C   . VAL E 1 160 ? 117.826 131.919 101.177 1.00 42.26  ? 106 VAL E C   1 
ATOM   11919 O O   . VAL E 1 160 ? 118.864 131.379 100.777 1.00 48.21  ? 106 VAL E O   1 
ATOM   11920 C CB  . VAL E 1 160 ? 117.503 133.877 99.620  1.00 35.56  ? 106 VAL E CB  1 
ATOM   11921 C CG1 . VAL E 1 160 ? 116.289 133.218 98.990  1.00 35.74  ? 106 VAL E CG1 1 
ATOM   11922 C CG2 . VAL E 1 160 ? 117.392 135.387 99.542  1.00 35.37  ? 106 VAL E CG2 1 
ATOM   11923 N N   . HIS E 1 161 ? 116.810 131.245 101.706 1.00 37.99  ? 107 HIS E N   1 
ATOM   11924 C CA  . HIS E 1 161 ? 116.886 129.806 101.917 1.00 40.94  ? 107 HIS E CA  1 
ATOM   11925 C C   . HIS E 1 161 ? 117.004 129.073 100.586 1.00 43.91  ? 107 HIS E C   1 
ATOM   11926 O O   . HIS E 1 161 ? 116.357 129.433 99.600  1.00 50.27  ? 107 HIS E O   1 
ATOM   11927 C CB  . HIS E 1 161 ? 115.658 129.322 102.685 1.00 39.14  ? 107 HIS E CB  1 
ATOM   11928 C CG  . HIS E 1 161 ? 115.493 129.962 104.028 1.00 39.19  ? 107 HIS E CG  1 
ATOM   11929 N ND1 . HIS E 1 161 ? 115.508 129.241 105.203 1.00 40.59  ? 107 HIS E ND1 1 
ATOM   11930 C CD2 . HIS E 1 161 ? 115.313 131.256 104.385 1.00 41.48  ? 107 HIS E CD2 1 
ATOM   11931 C CE1 . HIS E 1 161 ? 115.342 130.063 106.224 1.00 38.80  ? 107 HIS E CE1 1 
ATOM   11932 N NE2 . HIS E 1 161 ? 115.223 131.291 105.755 1.00 39.41  ? 107 HIS E NE2 1 
ATOM   11933 N N   . GLY E 1 162 ? 117.843 128.038 100.559 1.00 38.74  ? 108 GLY E N   1 
ATOM   11934 C CA  . GLY E 1 162 ? 118.135 127.348 99.319  1.00 39.04  ? 108 GLY E CA  1 
ATOM   11935 C C   . GLY E 1 162 ? 118.012 125.839 99.360  1.00 46.76  ? 108 GLY E C   1 
ATOM   11936 O O   . GLY E 1 162 ? 118.801 125.138 98.721  1.00 54.11  ? 108 GLY E O   1 
ATOM   11937 N N   . VAL E 1 163 ? 117.040 125.321 100.107 1.00 45.72  ? 109 VAL E N   1 
ATOM   11938 C CA  . VAL E 1 163 ? 116.764 123.890 100.163 1.00 38.53  ? 109 VAL E CA  1 
ATOM   11939 C C   . VAL E 1 163 ? 115.269 123.684 99.961  1.00 38.48  ? 109 VAL E C   1 
ATOM   11940 O O   . VAL E 1 163 ? 114.458 124.317 100.645 1.00 41.62  ? 109 VAL E O   1 
ATOM   11941 C CB  . VAL E 1 163 ? 117.230 123.270 101.495 1.00 36.28  ? 109 VAL E CB  1 
ATOM   11942 C CG1 . VAL E 1 163 ? 116.611 121.901 101.694 1.00 33.99  ? 109 VAL E CG1 1 
ATOM   11943 C CG2 . VAL E 1 163 ? 118.744 123.169 101.521 1.00 43.27  ? 109 VAL E CG2 1 
ATOM   11944 N N   . THR E 1 164 ? 114.901 122.805 99.028  1.00 39.10  ? 110 THR E N   1 
ATOM   11945 C CA  . THR E 1 164 ? 115.842 122.048 98.203  1.00 38.39  ? 110 THR E CA  1 
ATOM   11946 C C   . THR E 1 164 ? 116.384 122.897 97.061  1.00 43.68  ? 110 THR E C   1 
ATOM   11947 O O   . THR E 1 164 ? 117.540 122.765 96.665  1.00 47.01  ? 110 THR E O   1 
ATOM   11948 C CB  . THR E 1 164 ? 115.183 120.788 97.620  1.00 38.00  ? 110 THR E CB  1 
ATOM   11949 O OG1 . THR E 1 164 ? 114.161 121.169 96.692  1.00 38.08  ? 110 THR E OG1 1 
ATOM   11950 C CG2 . THR E 1 164 ? 114.561 119.953 98.726  1.00 37.23  ? 110 THR E CG2 1 
ATOM   11951 N N   . VAL E 1 165 ? 115.528 123.765 96.534  1.00 46.58  ? 111 VAL E N   1 
ATOM   11952 C CA  . VAL E 1 165 ? 115.931 124.782 95.579  1.00 45.99  ? 111 VAL E CA  1 
ATOM   11953 C C   . VAL E 1 165 ? 115.916 126.126 96.297  1.00 47.07  ? 111 VAL E C   1 
ATOM   11954 O O   . VAL E 1 165 ? 115.460 126.241 97.435  1.00 49.25  ? 111 VAL E O   1 
ATOM   11955 C CB  . VAL E 1 165 ? 115.024 124.801 94.335  1.00 42.46  ? 111 VAL E CB  1 
ATOM   11956 C CG1 . VAL E 1 165 ? 114.893 123.403 93.758  1.00 43.75  ? 111 VAL E CG1 1 
ATOM   11957 C CG2 . VAL E 1 165 ? 113.660 125.366 94.685  1.00 38.77  ? 111 VAL E CG2 1 
ATOM   11958 N N   . LYS E 1 166 ? 116.440 127.150 95.628  1.00 46.60  ? 112 LYS E N   1 
ATOM   11959 C CA  . LYS E 1 166 ? 116.365 128.492 96.187  1.00 46.08  ? 112 LYS E CA  1 
ATOM   11960 C C   . LYS E 1 166 ? 114.906 128.873 96.391  1.00 46.34  ? 112 LYS E C   1 
ATOM   11961 O O   . LYS E 1 166 ? 114.101 128.809 95.459  1.00 48.44  ? 112 LYS E O   1 
ATOM   11962 C CB  . LYS E 1 166 ? 117.055 129.499 95.268  1.00 45.10  ? 112 LYS E CB  1 
ATOM   11963 C CG  . LYS E 1 166 ? 118.544 129.264 95.089  1.00 53.89  ? 112 LYS E CG  1 
ATOM   11964 C CD  . LYS E 1 166 ? 119.205 130.456 94.419  1.00 64.01  ? 112 LYS E CD  1 
ATOM   11965 C CE  . LYS E 1 166 ? 118.996 131.722 95.233  1.00 65.09  ? 112 LYS E CE  1 
ATOM   11966 N NZ  . LYS E 1 166 ? 119.498 131.567 96.626  1.00 57.12  ? 112 LYS E NZ  1 
ATOM   11967 N N   . ASN E 1 167 ? 114.564 129.263 97.617  1.00 45.09  ? 113 ASN E N   1 
ATOM   11968 C CA  . ASN E 1 167 ? 113.172 129.546 97.935  1.00 39.11  ? 113 ASN E CA  1 
ATOM   11969 C C   . ASN E 1 167 ? 112.748 130.821 97.229  1.00 40.98  ? 113 ASN E C   1 
ATOM   11970 O O   . ASN E 1 167 ? 112.923 131.925 97.752  1.00 41.84  ? 113 ASN E O   1 
ATOM   11971 C CB  . ASN E 1 167 ? 112.963 129.658 99.444  1.00 37.23  ? 113 ASN E CB  1 
ATOM   11972 C CG  . ASN E 1 167 ? 113.090 128.325 100.149 1.00 40.20  ? 113 ASN E CG  1 
ATOM   11973 O OD1 . ASN E 1 167 ? 112.983 128.245 101.371 1.00 42.01  ? 113 ASN E OD1 1 
ATOM   11974 N ND2 . ASN E 1 167 ? 113.324 127.268 99.380  1.00 44.61  ? 113 ASN E ND2 1 
ATOM   11975 N N   . ARG E 1 168 ? 112.182 130.665 96.038  1.00 41.63  ? 114 ARG E N   1 
ATOM   11976 C CA  . ARG E 1 168 ? 111.934 131.787 95.152  1.00 36.77  ? 114 ARG E CA  1 
ATOM   11977 C C   . ARG E 1 168 ? 110.799 131.415 94.214  1.00 45.20  ? 114 ARG E C   1 
ATOM   11978 O O   . ARG E 1 168 ? 110.660 130.252 93.833  1.00 60.14  ? 114 ARG E O   1 
ATOM   11979 C CB  . ARG E 1 168 ? 113.201 132.142 94.371  1.00 34.60  ? 114 ARG E CB  1 
ATOM   11980 C CG  . ARG E 1 168 ? 113.042 133.243 93.357  1.00 38.89  ? 114 ARG E CG  1 
ATOM   11981 C CD  . ARG E 1 168 ? 114.400 133.684 92.866  1.00 50.98  ? 114 ARG E CD  1 
ATOM   11982 N NE  . ARG E 1 168 ? 115.214 132.549 92.450  1.00 57.82  ? 114 ARG E NE  1 
ATOM   11983 C CZ  . ARG E 1 168 ? 116.439 132.649 91.953  1.00 61.88  ? 114 ARG E CZ  1 
ATOM   11984 N NH1 . ARG E 1 168 ? 117.025 133.824 91.793  1.00 62.28  ? 114 ARG E NH1 1 
ATOM   11985 N NH2 . ARG E 1 168 ? 117.090 131.543 91.607  1.00 61.92  ? 114 ARG E NH2 1 
ATOM   11986 N N   . MET E 1 169 ? 109.986 132.405 93.864  1.00 37.70  ? 115 MET E N   1 
ATOM   11987 C CA  . MET E 1 169 ? 108.821 132.190 93.021  1.00 35.12  ? 115 MET E CA  1 
ATOM   11988 C C   . MET E 1 169 ? 108.729 133.306 91.997  1.00 38.92  ? 115 MET E C   1 
ATOM   11989 O O   . MET E 1 169 ? 108.814 134.484 92.357  1.00 45.97  ? 115 MET E O   1 
ATOM   11990 C CB  . MET E 1 169 ? 107.541 132.138 93.857  1.00 35.28  ? 115 MET E CB  1 
ATOM   11991 C CG  . MET E 1 169 ? 106.272 132.280 93.044  1.00 42.19  ? 115 MET E CG  1 
ATOM   11992 S SD  . MET E 1 169 ? 104.834 132.597 94.078  1.00 68.93  ? 115 MET E SD  1 
ATOM   11993 C CE  . MET E 1 169 ? 105.336 134.115 94.881  1.00 53.43  ? 115 MET E CE  1 
ATOM   11994 N N   . ILE E 1 170 ? 108.540 132.932 90.734  1.00 39.66  ? 116 ILE E N   1 
ATOM   11995 C CA  . ILE E 1 170 ? 108.358 133.872 89.635  1.00 37.73  ? 116 ILE E CA  1 
ATOM   11996 C C   . ILE E 1 170 ? 107.026 133.569 88.968  1.00 43.03  ? 116 ILE E C   1 
ATOM   11997 O O   . ILE E 1 170 ? 106.773 132.428 88.560  1.00 55.12  ? 116 ILE E O   1 
ATOM   11998 C CB  . ILE E 1 170 ? 109.506 133.786 88.614  1.00 39.01  ? 116 ILE E CB  1 
ATOM   11999 C CG1 . ILE E 1 170 ? 110.779 134.418 89.176  1.00 40.16  ? 116 ILE E CG1 1 
ATOM   12000 C CG2 . ILE E 1 170 ? 109.106 134.458 87.313  1.00 40.91  ? 116 ILE E CG2 1 
ATOM   12001 C CD1 . ILE E 1 170 ? 110.814 135.923 89.049  1.00 40.43  ? 116 ILE E CD1 1 
ATOM   12002 N N   . ARG E 1 171 ? 106.178 134.587 88.853  1.00 37.75  ? 117 ARG E N   1 
ATOM   12003 C CA  . ARG E 1 171 ? 104.894 134.442 88.184  1.00 42.44  ? 117 ARG E CA  1 
ATOM   12004 C C   . ARG E 1 171 ? 104.703 135.592 87.210  1.00 48.03  ? 117 ARG E C   1 
ATOM   12005 O O   . ARG E 1 171 ? 104.886 136.757 87.577  1.00 52.20  ? 117 ARG E O   1 
ATOM   12006 C CB  . ARG E 1 171 ? 103.748 134.398 89.193  1.00 39.63  ? 117 ARG E CB  1 
ATOM   12007 C CG  . ARG E 1 171 ? 102.423 133.980 88.597  1.00 44.90  ? 117 ARG E CG  1 
ATOM   12008 C CD  . ARG E 1 171 ? 101.410 133.757 89.692  1.00 47.71  ? 117 ARG E CD  1 
ATOM   12009 N NE  . ARG E 1 171 ? 101.865 132.743 90.634  1.00 53.90  ? 117 ARG E NE  1 
ATOM   12010 C CZ  . ARG E 1 171 ? 101.297 132.502 91.807  1.00 55.00  ? 117 ARG E CZ  1 
ATOM   12011 N NH1 . ARG E 1 171 ? 100.256 133.201 92.227  1.00 55.71  ? 117 ARG E NH1 1 
ATOM   12012 N NH2 . ARG E 1 171 ? 101.787 131.536 92.578  1.00 49.42  ? 117 ARG E NH2 1 
ATOM   12013 N N   . LEU E 1 172 ? 104.337 135.261 85.976  1.00 48.27  ? 118 LEU E N   1 
ATOM   12014 C CA  . LEU E 1 172 ? 104.084 136.239 84.930  1.00 49.09  ? 118 LEU E CA  1 
ATOM   12015 C C   . LEU E 1 172 ? 102.603 136.246 84.586  1.00 56.39  ? 118 LEU E C   1 
ATOM   12016 O O   . LEU E 1 172 ? 101.954 135.195 84.570  1.00 61.50  ? 118 LEU E O   1 
ATOM   12017 C CB  . LEU E 1 172 ? 104.904 135.933 83.677  1.00 48.53  ? 118 LEU E CB  1 
ATOM   12018 C CG  . LEU E 1 172 ? 106.420 135.857 83.845  1.00 45.05  ? 118 LEU E CG  1 
ATOM   12019 C CD1 . LEU E 1 172 ? 107.079 135.523 82.519  1.00 47.52  ? 118 LEU E CD1 1 
ATOM   12020 C CD2 . LEU E 1 172 ? 106.956 137.164 84.395  1.00 43.83  ? 118 LEU E CD2 1 
ATOM   12021 N N   . HIS E 1 173 ? 102.079 137.430 84.302  1.00 59.01  ? 119 HIS E N   1 
ATOM   12022 C CA  . HIS E 1 173 ? 100.677 137.637 83.989  1.00 61.19  ? 119 HIS E CA  1 
ATOM   12023 C C   . HIS E 1 173 ? 100.533 138.136 82.557  1.00 67.05  ? 119 HIS E C   1 
ATOM   12024 O O   . HIS E 1 173 ? 101.468 138.722 81.999  1.00 68.57  ? 119 HIS E O   1 
ATOM   12025 C CB  . HIS E 1 173 ? 100.049 138.639 84.967  1.00 60.18  ? 119 HIS E CB  1 
ATOM   12026 C CG  . HIS E 1 173 ? 100.190 138.243 86.403  1.00 63.83  ? 119 HIS E CG  1 
ATOM   12027 N ND1 . HIS E 1 173 ? 101.369 138.386 87.101  1.00 58.15  ? 119 HIS E ND1 1 
ATOM   12028 C CD2 . HIS E 1 173 ? 99.304  137.696 87.269  1.00 72.63  ? 119 HIS E CD2 1 
ATOM   12029 C CE1 . HIS E 1 173 ? 101.202 137.951 88.337  1.00 56.26  ? 119 HIS E CE1 1 
ATOM   12030 N NE2 . HIS E 1 173 ? 99.958  137.528 88.465  1.00 68.48  ? 119 HIS E NE2 1 
ATOM   12031 N N   . PRO E 1 174 ? 99.376  137.907 81.926  1.00 66.68  ? 120 PRO E N   1 
ATOM   12032 C CA  . PRO E 1 174 ? 99.238  138.268 80.503  1.00 65.77  ? 120 PRO E CA  1 
ATOM   12033 C C   . PRO E 1 174 ? 99.472  139.740 80.209  1.00 68.44  ? 120 PRO E C   1 
ATOM   12034 O O   . PRO E 1 174 ? 100.015 140.072 79.148  1.00 67.67  ? 120 PRO E O   1 
ATOM   12035 C CB  . PRO E 1 174 ? 97.797  137.848 80.182  1.00 71.19  ? 120 PRO E CB  1 
ATOM   12036 C CG  . PRO E 1 174 ? 97.484  136.788 81.176  1.00 75.11  ? 120 PRO E CG  1 
ATOM   12037 C CD  . PRO E 1 174 ? 98.192  137.191 82.430  1.00 69.03  ? 120 PRO E CD  1 
ATOM   12038 N N   . ASP E 1 175 ? 99.083  140.635 81.118  1.00 71.06  ? 121 ASP E N   1 
ATOM   12039 C CA  . ASP E 1 175 ? 99.258  142.063 80.882  1.00 71.18  ? 121 ASP E CA  1 
ATOM   12040 C C   . ASP E 1 175 ? 100.703 142.517 81.034  1.00 71.81  ? 121 ASP E C   1 
ATOM   12041 O O   . ASP E 1 175 ? 101.012 143.662 80.690  1.00 72.41  ? 121 ASP E O   1 
ATOM   12042 C CB  . ASP E 1 175 ? 98.363  142.865 81.828  1.00 68.12  ? 121 ASP E CB  1 
ATOM   12043 C CG  . ASP E 1 175 ? 98.660  142.590 83.287  1.00 74.15  ? 121 ASP E CG  1 
ATOM   12044 O OD1 . ASP E 1 175 ? 99.217  141.514 83.589  1.00 75.53  ? 121 ASP E OD1 1 
ATOM   12045 O OD2 . ASP E 1 175 ? 98.335  143.446 84.135  1.00 81.39  ? 121 ASP E OD2 1 
ATOM   12046 N N   . GLY E 1 176 ? 101.587 141.660 81.536  1.00 69.28  ? 122 GLY E N   1 
ATOM   12047 C CA  . GLY E 1 176 ? 102.969 142.020 81.765  1.00 63.28  ? 122 GLY E CA  1 
ATOM   12048 C C   . GLY E 1 176 ? 103.367 142.140 83.217  1.00 60.74  ? 122 GLY E C   1 
ATOM   12049 O O   . GLY E 1 176 ? 104.490 142.571 83.499  1.00 61.26  ? 122 GLY E O   1 
ATOM   12050 N N   . THR E 1 177 ? 102.489 141.772 84.143  1.00 60.80  ? 123 THR E N   1 
ATOM   12051 C CA  . THR E 1 177 ? 102.765 141.916 85.563  1.00 53.82  ? 123 THR E CA  1 
ATOM   12052 C C   . THR E 1 177 ? 103.655 140.783 86.053  1.00 51.86  ? 123 THR E C   1 
ATOM   12053 O O   . THR E 1 177 ? 103.502 139.630 85.642  1.00 64.19  ? 123 THR E O   1 
ATOM   12054 C CB  . THR E 1 177 ? 101.456 141.933 86.352  1.00 55.32  ? 123 THR E CB  1 
ATOM   12055 O OG1 . THR E 1 177 ? 100.513 142.783 85.690  1.00 64.66  ? 123 THR E OG1 1 
ATOM   12056 C CG2 . THR E 1 177 ? 101.690 142.458 87.744  1.00 50.92  ? 123 THR E CG2 1 
ATOM   12057 N N   . VAL E 1 178 ? 104.591 141.117 86.937  1.00 40.95  ? 124 VAL E N   1 
ATOM   12058 C CA  . VAL E 1 178 ? 105.545 140.165 87.489  1.00 39.27  ? 124 VAL E CA  1 
ATOM   12059 C C   . VAL E 1 178 ? 105.363 140.114 88.997  1.00 42.57  ? 124 VAL E C   1 
ATOM   12060 O O   . VAL E 1 178 ? 105.341 141.158 89.664  1.00 51.88  ? 124 VAL E O   1 
ATOM   12061 C CB  . VAL E 1 178 ? 106.995 140.541 87.134  1.00 36.91  ? 124 VAL E CB  1 
ATOM   12062 C CG1 . VAL E 1 178 ? 107.953 139.481 87.645  1.00 38.27  ? 124 VAL E CG1 1 
ATOM   12063 C CG2 . VAL E 1 178 ? 107.142 140.724 85.639  1.00 47.74  ? 124 VAL E CG2 1 
ATOM   12064 N N   . LEU E 1 179 ? 105.230 138.899 89.523  1.00 39.15  ? 125 LEU E N   1 
ATOM   12065 C CA  . LEU E 1 179 ? 105.201 138.634 90.954  1.00 38.27  ? 125 LEU E CA  1 
ATOM   12066 C C   . LEU E 1 179 ? 106.442 137.831 91.317  1.00 37.42  ? 125 LEU E C   1 
ATOM   12067 O O   . LEU E 1 179 ? 106.720 136.797 90.700  1.00 44.95  ? 125 LEU E O   1 
ATOM   12068 C CB  . LEU E 1 179 ? 103.935 137.872 91.346  1.00 41.29  ? 125 LEU E CB  1 
ATOM   12069 C CG  . LEU E 1 179 ? 103.822 137.399 92.794  1.00 40.69  ? 125 LEU E CG  1 
ATOM   12070 C CD1 . LEU E 1 179 ? 103.866 138.579 93.746  1.00 43.15  ? 125 LEU E CD1 1 
ATOM   12071 C CD2 . LEU E 1 179 ? 102.545 136.601 92.990  1.00 48.03  ? 125 LEU E CD2 1 
ATOM   12072 N N   . TYR E 1 180 ? 107.178 138.307 92.318  1.00 29.35  ? 126 TYR E N   1 
ATOM   12073 C CA  . TYR E 1 180 ? 108.505 137.790 92.636  1.00 30.02  ? 126 TYR E CA  1 
ATOM   12074 C C   . TYR E 1 180 ? 108.587 137.595 94.142  1.00 37.81  ? 126 TYR E C   1 
ATOM   12075 O O   . TYR E 1 180 ? 108.689 138.571 94.889  1.00 48.64  ? 126 TYR E O   1 
ATOM   12076 C CB  . TYR E 1 180 ? 109.581 138.755 92.141  1.00 29.94  ? 126 TYR E CB  1 
ATOM   12077 C CG  . TYR E 1 180 ? 110.997 138.365 92.469  1.00 29.86  ? 126 TYR E CG  1 
ATOM   12078 C CD1 . TYR E 1 180 ? 111.461 137.087 92.219  1.00 31.16  ? 126 TYR E CD1 1 
ATOM   12079 C CD2 . TYR E 1 180 ? 111.882 139.290 92.999  1.00 32.67  ? 126 TYR E CD2 1 
ATOM   12080 C CE1 . TYR E 1 180 ? 112.758 136.734 92.504  1.00 35.81  ? 126 TYR E CE1 1 
ATOM   12081 C CE2 . TYR E 1 180 ? 113.181 138.946 93.288  1.00 35.24  ? 126 TYR E CE2 1 
ATOM   12082 C CZ  . TYR E 1 180 ? 113.615 137.666 93.037  1.00 39.65  ? 126 TYR E CZ  1 
ATOM   12083 O OH  . TYR E 1 180 ? 114.912 137.315 93.324  1.00 42.56  ? 126 TYR E OH  1 
ATOM   12084 N N   . GLY E 1 181 ? 108.527 136.347 94.587  1.00 34.64  ? 127 GLY E N   1 
ATOM   12085 C CA  . GLY E 1 181 ? 108.499 136.021 96.007  1.00 33.01  ? 127 GLY E CA  1 
ATOM   12086 C C   . GLY E 1 181 ? 109.799 135.377 96.452  1.00 36.07  ? 127 GLY E C   1 
ATOM   12087 O O   . GLY E 1 181 ? 110.386 134.580 95.718  1.00 43.45  ? 127 GLY E O   1 
ATOM   12088 N N   . LEU E 1 182 ? 110.239 135.727 97.659  1.00 32.80  ? 128 LEU E N   1 
ATOM   12089 C CA  . LEU E 1 182 ? 111.429 135.154 98.266  1.00 30.48  ? 128 LEU E CA  1 
ATOM   12090 C C   . LEU E 1 182 ? 111.131 134.794 99.713  1.00 34.20  ? 128 LEU E C   1 
ATOM   12091 O O   . LEU E 1 182 ? 110.239 135.370 100.337 1.00 40.56  ? 128 LEU E O   1 
ATOM   12092 C CB  . LEU E 1 182 ? 112.614 136.126 98.214  1.00 26.94  ? 128 LEU E CB  1 
ATOM   12093 C CG  . LEU E 1 182 ? 113.140 136.535 96.840  1.00 29.04  ? 128 LEU E CG  1 
ATOM   12094 C CD1 . LEU E 1 182 ? 114.050 137.737 96.973  1.00 33.76  ? 128 LEU E CD1 1 
ATOM   12095 C CD2 . LEU E 1 182 ? 113.884 135.380 96.205  1.00 34.91  ? 128 LEU E CD2 1 
ATOM   12096 N N   . ARG E 1 183 ? 111.868 133.821 100.238 1.00 32.82  ? 129 ARG E N   1 
ATOM   12097 C CA  . ARG E 1 183 ? 111.813 133.478 101.653 1.00 33.91  ? 129 ARG E CA  1 
ATOM   12098 C C   . ARG E 1 183 ? 113.120 133.919 102.290 1.00 34.07  ? 129 ARG E C   1 
ATOM   12099 O O   . ARG E 1 183 ? 114.190 133.420 101.926 1.00 40.09  ? 129 ARG E O   1 
ATOM   12100 C CB  . ARG E 1 183 ? 111.579 131.982 101.859 1.00 35.72  ? 129 ARG E CB  1 
ATOM   12101 C CG  . ARG E 1 183 ? 111.152 131.624 103.271 1.00 33.72  ? 129 ARG E CG  1 
ATOM   12102 C CD  . ARG E 1 183 ? 110.507 130.252 103.330 1.00 37.09  ? 129 ARG E CD  1 
ATOM   12103 N NE  . ARG E 1 183 ? 111.491 129.178 103.368 1.00 44.52  ? 129 ARG E NE  1 
ATOM   12104 C CZ  . ARG E 1 183 ? 111.913 128.592 104.479 1.00 42.18  ? 129 ARG E CZ  1 
ATOM   12105 N NH1 . ARG E 1 183 ? 111.456 128.952 105.667 1.00 34.77  ? 129 ARG E NH1 1 
ATOM   12106 N NH2 . ARG E 1 183 ? 112.814 127.617 104.396 1.00 44.24  ? 129 ARG E NH2 1 
ATOM   12107 N N   . ILE E 1 184 ? 113.034 134.850 103.235 1.00 30.06  ? 130 ILE E N   1 
ATOM   12108 C CA  . ILE E 1 184 ? 114.201 135.550 103.755 1.00 28.73  ? 130 ILE E CA  1 
ATOM   12109 C C   . ILE E 1 184 ? 114.263 135.383 105.265 1.00 36.45  ? 130 ILE E C   1 
ATOM   12110 O O   . ILE E 1 184 ? 113.239 135.460 105.952 1.00 44.40  ? 130 ILE E O   1 
ATOM   12111 C CB  . ILE E 1 184 ? 114.168 137.047 103.378 1.00 29.05  ? 130 ILE E CB  1 
ATOM   12112 C CG1 . ILE E 1 184 ? 114.083 137.217 101.861 1.00 27.38  ? 130 ILE E CG1 1 
ATOM   12113 C CG2 . ILE E 1 184 ? 115.385 137.769 103.926 1.00 34.16  ? 130 ILE E CG2 1 
ATOM   12114 C CD1 . ILE E 1 184 ? 114.073 138.656 101.413 1.00 23.09  ? 130 ILE E CD1 1 
ATOM   12115 N N   . THR E 1 185 ? 115.469 135.157 105.778 1.00 38.75  ? 131 THR E N   1 
ATOM   12116 C CA  . THR E 1 185 ? 115.758 135.240 107.203 1.00 41.63  ? 131 THR E CA  1 
ATOM   12117 C C   . THR E 1 185 ? 116.769 136.359 107.404 1.00 45.74  ? 131 THR E C   1 
ATOM   12118 O O   . THR E 1 185 ? 117.858 136.325 106.823 1.00 48.74  ? 131 THR E O   1 
ATOM   12119 C CB  . THR E 1 185 ? 116.300 133.916 107.742 1.00 41.10  ? 131 THR E CB  1 
ATOM   12120 O OG1 . THR E 1 185 ? 115.312 132.891 107.582 1.00 45.60  ? 131 THR E OG1 1 
ATOM   12121 C CG2 . THR E 1 185 ? 116.650 134.043 109.214 1.00 38.86  ? 131 THR E CG2 1 
ATOM   12122 N N   . THR E 1 186 ? 116.410 137.342 108.226 1.00 49.13  ? 132 THR E N   1 
ATOM   12123 C CA  . THR E 1 186 ? 117.201 138.553 108.388 1.00 51.55  ? 132 THR E CA  1 
ATOM   12124 C C   . THR E 1 186 ? 117.362 138.884 109.864 1.00 51.77  ? 132 THR E C   1 
ATOM   12125 O O   . THR E 1 186 ? 116.406 138.794 110.637 1.00 51.74  ? 132 THR E O   1 
ATOM   12126 C CB  . THR E 1 186 ? 116.554 139.739 107.652 1.00 57.48  ? 132 THR E CB  1 
ATOM   12127 O OG1 . THR E 1 186 ? 117.152 140.966 108.087 1.00 63.43  ? 132 THR E OG1 1 
ATOM   12128 C CG2 . THR E 1 186 ? 115.057 139.785 107.912 1.00 54.13  ? 132 THR E CG2 1 
ATOM   12129 N N   . THR E 1 187 ? 118.574 139.271 110.249 1.00 51.45  ? 133 THR E N   1 
ATOM   12130 C CA  . THR E 1 187 ? 118.862 139.713 111.612 1.00 53.14  ? 133 THR E CA  1 
ATOM   12131 C C   . THR E 1 187 ? 118.896 141.237 111.590 1.00 52.83  ? 133 THR E C   1 
ATOM   12132 O O   . THR E 1 187 ? 119.917 141.849 111.285 1.00 55.49  ? 133 THR E O   1 
ATOM   12133 C CB  . THR E 1 187 ? 120.173 139.122 112.118 1.00 56.47  ? 133 THR E CB  1 
ATOM   12134 O OG1 . THR E 1 187 ? 120.153 137.700 111.954 1.00 62.86  ? 133 THR E OG1 1 
ATOM   12135 C CG2 . THR E 1 187 ? 120.367 139.447 113.587 1.00 53.73  ? 133 THR E CG2 1 
ATOM   12136 N N   . ALA E 1 188 ? 117.764 141.852 111.910 1.00 55.39  ? 134 ALA E N   1 
ATOM   12137 C CA  . ALA E 1 188 ? 117.639 143.300 111.851 1.00 55.46  ? 134 ALA E CA  1 
ATOM   12138 C C   . ALA E 1 188 ? 118.058 143.923 113.174 1.00 52.66  ? 134 ALA E C   1 
ATOM   12139 O O   . ALA E 1 188 ? 117.662 143.458 114.245 1.00 57.33  ? 134 ALA E O   1 
ATOM   12140 C CB  . ALA E 1 188 ? 116.205 143.705 111.511 1.00 52.62  ? 134 ALA E CB  1 
ATOM   12141 N N   . ALA E 1 189 ? 118.852 144.986 113.091 1.00 48.21  ? 135 ALA E N   1 
ATOM   12142 C CA  . ALA E 1 189 ? 119.367 145.654 114.280 1.00 51.81  ? 135 ALA E CA  1 
ATOM   12143 C C   . ALA E 1 189 ? 118.304 146.583 114.853 1.00 54.41  ? 135 ALA E C   1 
ATOM   12144 O O   . ALA E 1 189 ? 117.881 147.535 114.189 1.00 56.34  ? 135 ALA E O   1 
ATOM   12145 C CB  . ALA E 1 189 ? 120.636 146.432 113.946 1.00 46.85  ? 135 ALA E CB  1 
ATOM   12146 N N   . CYS E 1 190 ? 117.878 146.310 116.082 1.00 56.46  ? 136 CYS E N   1 
ATOM   12147 C CA  . CYS E 1 190 ? 116.877 147.115 116.779 1.00 61.00  ? 136 CYS E CA  1 
ATOM   12148 C C   . CYS E 1 190 ? 117.527 147.705 118.024 1.00 68.70  ? 136 CYS E C   1 
ATOM   12149 O O   . CYS E 1 190 ? 117.740 146.998 119.013 1.00 77.84  ? 136 CYS E O   1 
ATOM   12150 C CB  . CYS E 1 190 ? 115.651 146.279 117.134 1.00 65.59  ? 136 CYS E CB  1 
ATOM   12151 S SG  . CYS E 1 190 ? 114.417 147.146 118.132 1.00 84.21  ? 136 CYS E SG  1 
ATOM   12152 N N   . MET E 1 191 ? 117.842 148.998 117.977 1.00 67.81  ? 137 MET E N   1 
ATOM   12153 C CA  . MET E 1 191 ? 118.411 149.668 119.138 1.00 70.51  ? 137 MET E CA  1 
ATOM   12154 C C   . MET E 1 191 ? 117.339 149.849 120.204 1.00 74.53  ? 137 MET E C   1 
ATOM   12155 O O   . MET E 1 191 ? 116.226 150.296 119.911 1.00 70.19  ? 137 MET E O   1 
ATOM   12156 C CB  . MET E 1 191 ? 119.001 151.018 118.738 1.00 67.55  ? 137 MET E CB  1 
ATOM   12157 C CG  . MET E 1 191 ? 120.104 150.938 117.690 1.00 75.71  ? 137 MET E CG  1 
ATOM   12158 S SD  . MET E 1 191 ? 121.562 150.035 118.251 1.00 92.56  ? 137 MET E SD  1 
ATOM   12159 C CE  . MET E 1 191 ? 121.402 148.510 117.326 1.00 74.53  ? 137 MET E CE  1 
ATOM   12160 N N   . MET E 1 192 ? 117.671 149.498 121.442 1.00 75.44  ? 138 MET E N   1 
ATOM   12161 C CA  . MET E 1 192 ? 116.706 149.476 122.531 1.00 70.61  ? 138 MET E CA  1 
ATOM   12162 C C   . MET E 1 192 ? 117.138 150.415 123.645 1.00 73.63  ? 138 MET E C   1 
ATOM   12163 O O   . MET E 1 192 ? 118.323 150.492 123.984 1.00 78.95  ? 138 MET E O   1 
ATOM   12164 C CB  . MET E 1 192 ? 116.539 148.061 123.087 1.00 64.67  ? 138 MET E CB  1 
ATOM   12165 C CG  . MET E 1 192 ? 116.156 147.035 122.044 1.00 69.89  ? 138 MET E CG  1 
ATOM   12166 S SD  . MET E 1 192 ? 115.899 145.399 122.749 1.00 79.07  ? 138 MET E SD  1 
ATOM   12167 C CE  . MET E 1 192 ? 115.742 144.429 121.256 1.00 76.34  ? 138 MET E CE  1 
ATOM   12168 N N   . ASP E 1 193 ? 116.168 151.125 124.210 1.00 73.56  ? 139 ASP E N   1 
ATOM   12169 C CA  . ASP E 1 193 ? 116.380 151.964 125.381 1.00 73.33  ? 139 ASP E CA  1 
ATOM   12170 C C   . ASP E 1 193 ? 115.920 151.187 126.608 1.00 73.68  ? 139 ASP E C   1 
ATOM   12171 O O   . ASP E 1 193 ? 114.760 150.767 126.681 1.00 75.96  ? 139 ASP E O   1 
ATOM   12172 C CB  . ASP E 1 193 ? 115.621 153.283 125.254 1.00 72.51  ? 139 ASP E CB  1 
ATOM   12173 C CG  . ASP E 1 193 ? 115.963 154.261 126.357 1.00 77.30  ? 139 ASP E CG  1 
ATOM   12174 O OD1 . ASP E 1 193 ? 116.933 154.007 127.101 1.00 83.08  ? 139 ASP E OD1 1 
ATOM   12175 O OD2 . ASP E 1 193 ? 115.262 155.286 126.482 1.00 74.03  ? 139 ASP E OD2 1 
ATOM   12176 N N   . LEU E 1 194 ? 116.826 150.995 127.566 1.00 70.92  ? 140 LEU E N   1 
ATOM   12177 C CA  . LEU E 1 194 ? 116.570 150.150 128.724 1.00 66.18  ? 140 LEU E CA  1 
ATOM   12178 C C   . LEU E 1 194 ? 116.398 150.950 130.009 1.00 70.76  ? 140 LEU E C   1 
ATOM   12179 O O   . LEU E 1 194 ? 116.527 150.391 131.102 1.00 72.35  ? 140 LEU E O   1 
ATOM   12180 C CB  . LEU E 1 194 ? 117.692 149.125 128.887 1.00 61.36  ? 140 LEU E CB  1 
ATOM   12181 C CG  . LEU E 1 194 ? 117.922 148.193 127.696 1.00 64.74  ? 140 LEU E CG  1 
ATOM   12182 C CD1 . LEU E 1 194 ? 119.003 147.175 128.012 1.00 63.86  ? 140 LEU E CD1 1 
ATOM   12183 C CD2 . LEU E 1 194 ? 116.629 147.499 127.306 1.00 65.75  ? 140 LEU E CD2 1 
ATOM   12184 N N   . ARG E 1 195 ? 116.102 152.247 129.905 1.00 68.04  ? 141 ARG E N   1 
ATOM   12185 C CA  . ARG E 1 195 ? 115.922 153.057 131.104 1.00 62.66  ? 141 ARG E CA  1 
ATOM   12186 C C   . ARG E 1 195 ? 114.715 152.625 131.925 1.00 68.41  ? 141 ARG E C   1 
ATOM   12187 O O   . ARG E 1 195 ? 114.621 152.990 133.101 1.00 78.46  ? 141 ARG E O   1 
ATOM   12188 C CB  . ARG E 1 195 ? 115.799 154.532 130.731 1.00 66.13  ? 141 ARG E CB  1 
ATOM   12189 C CG  . ARG E 1 195 ? 117.121 155.180 130.370 1.00 72.17  ? 141 ARG E CG  1 
ATOM   12190 C CD  . ARG E 1 195 ? 116.943 156.638 129.997 1.00 75.31  ? 141 ARG E CD  1 
ATOM   12191 N NE  . ARG E 1 195 ? 118.221 157.337 129.935 1.00 83.69  ? 141 ARG E NE  1 
ATOM   12192 C CZ  . ARG E 1 195 ? 119.004 157.374 128.866 1.00 85.87  ? 141 ARG E CZ  1 
ATOM   12193 N NH1 . ARG E 1 195 ? 118.672 156.757 127.744 1.00 83.07  ? 141 ARG E NH1 1 
ATOM   12194 N NH2 . ARG E 1 195 ? 120.150 158.047 128.925 1.00 89.12  ? 141 ARG E NH2 1 
ATOM   12195 N N   . ARG E 1 196 ? 113.794 151.862 131.339 1.00 67.35  ? 142 ARG E N   1 
ATOM   12196 C CA  . ARG E 1 196 ? 112.638 151.345 132.059 1.00 67.49  ? 142 ARG E CA  1 
ATOM   12197 C C   . ARG E 1 196 ? 112.633 149.825 132.127 1.00 69.32  ? 142 ARG E C   1 
ATOM   12198 O O   . ARG E 1 196 ? 111.630 149.237 132.546 1.00 72.94  ? 142 ARG E O   1 
ATOM   12199 C CB  . ARG E 1 196 ? 111.346 151.851 131.416 1.00 62.22  ? 142 ARG E CB  1 
ATOM   12200 C CG  . ARG E 1 196 ? 111.247 153.362 131.376 1.00 64.98  ? 142 ARG E CG  1 
ATOM   12201 C CD  . ARG E 1 196 ? 110.017 153.812 130.618 1.00 75.02  ? 142 ARG E CD  1 
ATOM   12202 N NE  . ARG E 1 196 ? 108.790 153.357 131.259 1.00 77.54  ? 142 ARG E NE  1 
ATOM   12203 C CZ  . ARG E 1 196 ? 108.163 154.016 132.223 1.00 90.17  ? 142 ARG E CZ  1 
ATOM   12204 N NH1 . ARG E 1 196 ? 108.631 155.161 132.694 1.00 92.31  ? 142 ARG E NH1 1 
ATOM   12205 N NH2 . ARG E 1 196 ? 107.039 153.516 132.726 1.00 95.73  ? 142 ARG E NH2 1 
ATOM   12206 N N   . TYR E 1 197 ? 113.721 149.183 131.722 1.00 71.26  ? 143 TYR E N   1 
ATOM   12207 C CA  . TYR E 1 197 ? 113.812 147.733 131.771 1.00 68.96  ? 143 TYR E CA  1 
ATOM   12208 C C   . TYR E 1 197 ? 113.635 147.248 133.208 1.00 71.72  ? 143 TYR E C   1 
ATOM   12209 O O   . TYR E 1 197 ? 114.157 147.870 134.141 1.00 79.22  ? 143 TYR E O   1 
ATOM   12210 C CB  . TYR E 1 197 ? 115.167 147.292 131.216 1.00 72.34  ? 143 TYR E CB  1 
ATOM   12211 C CG  . TYR E 1 197 ? 115.453 145.811 131.262 1.00 73.96  ? 143 TYR E CG  1 
ATOM   12212 C CD1 . TYR E 1 197 ? 115.120 144.987 130.198 1.00 77.45  ? 143 TYR E CD1 1 
ATOM   12213 C CD2 . TYR E 1 197 ? 116.091 145.243 132.356 1.00 71.56  ? 143 TYR E CD2 1 
ATOM   12214 C CE1 . TYR E 1 197 ? 115.394 143.637 130.231 1.00 82.27  ? 143 TYR E CE1 1 
ATOM   12215 C CE2 . TYR E 1 197 ? 116.366 143.896 132.399 1.00 79.59  ? 143 TYR E CE2 1 
ATOM   12216 C CZ  . TYR E 1 197 ? 116.018 143.098 131.334 1.00 81.77  ? 143 TYR E CZ  1 
ATOM   12217 O OH  . TYR E 1 197 ? 116.298 141.753 131.374 1.00 80.60  ? 143 TYR E OH  1 
ATOM   12218 N N   . PRO E 1 198 ? 112.904 146.147 133.429 1.00 68.85  ? 144 PRO E N   1 
ATOM   12219 C CA  . PRO E 1 198 ? 112.230 145.292 132.445 1.00 69.07  ? 144 PRO E CA  1 
ATOM   12220 C C   . PRO E 1 198 ? 110.797 145.719 132.143 1.00 71.80  ? 144 PRO E C   1 
ATOM   12221 O O   . PRO E 1 198 ? 110.053 144.974 131.516 1.00 81.16  ? 144 PRO E O   1 
ATOM   12222 C CB  . PRO E 1 198 ? 112.272 143.922 133.122 1.00 76.78  ? 144 PRO E CB  1 
ATOM   12223 C CG  . PRO E 1 198 ? 112.092 144.256 134.573 1.00 76.36  ? 144 PRO E CG  1 
ATOM   12224 C CD  . PRO E 1 198 ? 112.834 145.561 134.780 1.00 75.59  ? 144 PRO E CD  1 
ATOM   12225 N N   . LEU E 1 199 ? 110.372 146.905 132.577 1.00 67.80  ? 145 LEU E N   1 
ATOM   12226 C CA  . LEU E 1 199 ? 109.033 147.410 132.298 1.00 68.71  ? 145 LEU E CA  1 
ATOM   12227 C C   . LEU E 1 199 ? 109.015 148.337 131.090 1.00 70.49  ? 145 LEU E C   1 
ATOM   12228 O O   . LEU E 1 199 ? 108.246 149.304 131.058 1.00 69.81  ? 145 LEU E O   1 
ATOM   12229 C CB  . LEU E 1 199 ? 108.461 148.128 133.521 1.00 72.13  ? 145 LEU E CB  1 
ATOM   12230 C CG  . LEU E 1 199 ? 108.146 147.302 134.771 1.00 73.29  ? 145 LEU E CG  1 
ATOM   12231 C CD1 . LEU E 1 199 ? 109.383 147.106 135.636 1.00 66.87  ? 145 LEU E CD1 1 
ATOM   12232 C CD2 . LEU E 1 199 ? 107.027 147.950 135.572 1.00 79.29  ? 145 LEU E CD2 1 
ATOM   12233 N N   . ASP E 1 200 ? 109.848 148.059 130.094 1.00 75.79  ? 146 ASP E N   1 
ATOM   12234 C CA  . ASP E 1 200 ? 110.043 148.939 128.954 1.00 75.47  ? 146 ASP E CA  1 
ATOM   12235 C C   . ASP E 1 200 ? 109.251 148.451 127.749 1.00 71.26  ? 146 ASP E C   1 
ATOM   12236 O O   . ASP E 1 200 ? 109.073 147.248 127.541 1.00 72.13  ? 146 ASP E O   1 
ATOM   12237 C CB  . ASP E 1 200 ? 111.527 149.028 128.593 1.00 75.11  ? 146 ASP E CB  1 
ATOM   12238 C CG  . ASP E 1 200 ? 112.145 147.667 128.347 1.00 78.32  ? 146 ASP E CG  1 
ATOM   12239 O OD1 . ASP E 1 200 ? 111.646 146.676 128.920 1.00 80.73  ? 146 ASP E OD1 1 
ATOM   12240 O OD2 . ASP E 1 200 ? 113.128 147.587 127.581 1.00 79.04  ? 146 ASP E OD2 1 
ATOM   12241 N N   . GLU E 1 201 ? 108.772 149.406 126.955 1.00 70.24  ? 147 GLU E N   1 
ATOM   12242 C CA  . GLU E 1 201 ? 108.066 149.132 125.710 1.00 71.65  ? 147 GLU E CA  1 
ATOM   12243 C C   . GLU E 1 201 ? 108.971 149.562 124.563 1.00 71.15  ? 147 GLU E C   1 
ATOM   12244 O O   . GLU E 1 201 ? 109.282 150.749 124.422 1.00 70.81  ? 147 GLU E O   1 
ATOM   12245 C CB  . GLU E 1 201 ? 106.726 149.863 125.667 1.00 74.94  ? 147 GLU E CB  1 
ATOM   12246 C CG  . GLU E 1 201 ? 105.839 149.470 124.499 1.00 83.32  ? 147 GLU E CG  1 
ATOM   12247 C CD  . GLU E 1 201 ? 104.503 150.188 124.510 1.00 92.89  ? 147 GLU E CD  1 
ATOM   12248 O OE1 . GLU E 1 201 ? 104.372 151.194 125.238 1.00 100.64 ? 147 GLU E OE1 1 
ATOM   12249 O OE2 . GLU E 1 201 ? 103.582 149.745 123.794 1.00 88.97  ? 147 GLU E OE2 1 
ATOM   12250 N N   . GLN E 1 202 ? 109.389 148.600 123.749 1.00 67.93  ? 148 GLN E N   1 
ATOM   12251 C CA  . GLN E 1 202 ? 110.353 148.841 122.686 1.00 64.30  ? 148 GLN E CA  1 
ATOM   12252 C C   . GLN E 1 202 ? 109.654 148.988 121.339 1.00 59.87  ? 148 GLN E C   1 
ATOM   12253 O O   . GLN E 1 202 ? 108.488 148.630 121.175 1.00 63.07  ? 148 GLN E O   1 
ATOM   12254 C CB  . GLN E 1 202 ? 111.381 147.707 122.622 1.00 62.27  ? 148 GLN E CB  1 
ATOM   12255 C CG  . GLN E 1 202 ? 112.190 147.526 123.896 1.00 67.94  ? 148 GLN E CG  1 
ATOM   12256 C CD  . GLN E 1 202 ? 113.116 148.693 124.180 1.00 74.03  ? 148 GLN E CD  1 
ATOM   12257 O OE1 . GLN E 1 202 ? 113.394 149.510 123.304 1.00 76.18  ? 148 GLN E OE1 1 
ATOM   12258 N NE2 . GLN E 1 202 ? 113.602 148.775 125.413 1.00 81.46  ? 148 GLN E NE2 1 
ATOM   12259 N N   . ASN E 1 203 ? 110.391 149.525 120.369 1.00 56.81  ? 149 ASN E N   1 
ATOM   12260 C CA  . ASN E 1 203 ? 109.885 149.750 119.018 1.00 53.95  ? 149 ASN E CA  1 
ATOM   12261 C C   . ASN E 1 203 ? 110.940 149.270 118.032 1.00 53.24  ? 149 ASN E C   1 
ATOM   12262 O O   . ASN E 1 203 ? 111.960 149.939 117.837 1.00 56.69  ? 149 ASN E O   1 
ATOM   12263 C CB  . ASN E 1 203 ? 109.547 151.227 118.803 1.00 57.20  ? 149 ASN E CB  1 
ATOM   12264 C CG  . ASN E 1 203 ? 109.111 151.537 117.380 1.00 60.62  ? 149 ASN E CG  1 
ATOM   12265 O OD1 . ASN E 1 203 ? 108.769 150.645 116.607 1.00 59.23  ? 149 ASN E OD1 1 
ATOM   12266 N ND2 . ASN E 1 203 ? 109.116 152.820 117.037 1.00 65.73  ? 149 ASN E ND2 1 
ATOM   12267 N N   . CYS E 1 204 ? 110.696 148.121 117.408 1.00 54.13  ? 150 CYS E N   1 
ATOM   12268 C CA  . CYS E 1 204 ? 111.647 147.509 116.488 1.00 55.34  ? 150 CYS E CA  1 
ATOM   12269 C C   . CYS E 1 204 ? 111.128 147.620 115.063 1.00 54.76  ? 150 CYS E C   1 
ATOM   12270 O O   . CYS E 1 204 ? 109.980 147.259 114.785 1.00 55.97  ? 150 CYS E O   1 
ATOM   12271 C CB  . CYS E 1 204 ? 111.903 146.044 116.847 1.00 54.32  ? 150 CYS E CB  1 
ATOM   12272 S SG  . CYS E 1 204 ? 112.895 145.815 118.341 1.00 80.22  ? 150 CYS E SG  1 
ATOM   12273 N N   . THR E 1 205 ? 111.976 148.106 114.161 1.00 54.06  ? 151 THR E N   1 
ATOM   12274 C CA  . THR E 1 205 ? 111.565 148.421 112.804 1.00 46.53  ? 151 THR E CA  1 
ATOM   12275 C C   . THR E 1 205 ? 112.306 147.557 111.792 1.00 48.70  ? 151 THR E C   1 
ATOM   12276 O O   . THR E 1 205 ? 113.357 146.979 112.077 1.00 56.02  ? 151 THR E O   1 
ATOM   12277 C CB  . THR E 1 205 ? 111.810 149.898 112.473 1.00 47.68  ? 151 THR E CB  1 
ATOM   12278 O OG1 . THR E 1 205 ? 113.185 150.083 112.119 1.00 57.83  ? 151 THR E OG1 1 
ATOM   12279 C CG2 . THR E 1 205 ? 111.486 150.772 113.670 1.00 53.97  ? 151 THR E CG2 1 
ATOM   12280 N N   . LEU E 1 206 ? 111.727 147.489 110.598 1.00 46.74  ? 152 LEU E N   1 
ATOM   12281 C CA  . LEU E 1 206 ? 112.334 146.861 109.431 1.00 43.29  ? 152 LEU E CA  1 
ATOM   12282 C C   . LEU E 1 206 ? 112.216 147.860 108.290 1.00 47.02  ? 152 LEU E C   1 
ATOM   12283 O O   . LEU E 1 206 ? 111.103 148.188 107.862 1.00 49.46  ? 152 LEU E O   1 
ATOM   12284 C CB  . LEU E 1 206 ? 111.647 145.541 109.084 1.00 36.63  ? 152 LEU E CB  1 
ATOM   12285 C CG  . LEU E 1 206 ? 112.138 144.815 107.831 1.00 38.92  ? 152 LEU E CG  1 
ATOM   12286 C CD1 . LEU E 1 206 ? 113.576 144.350 108.002 1.00 43.86  ? 152 LEU E CD1 1 
ATOM   12287 C CD2 . LEU E 1 206 ? 111.230 143.643 107.502 1.00 36.49  ? 152 LEU E CD2 1 
ATOM   12288 N N   . GLU E 1 207 ? 113.356 148.363 107.825 1.00 43.62  ? 153 GLU E N   1 
ATOM   12289 C CA  . GLU E 1 207 ? 113.409 149.402 106.808 1.00 39.21  ? 153 GLU E CA  1 
ATOM   12290 C C   . GLU E 1 207 ? 113.743 148.777 105.461 1.00 44.19  ? 153 GLU E C   1 
ATOM   12291 O O   . GLU E 1 207 ? 114.667 147.966 105.361 1.00 51.31  ? 153 GLU E O   1 
ATOM   12292 C CB  . GLU E 1 207 ? 114.449 150.461 107.171 1.00 46.95  ? 153 GLU E CB  1 
ATOM   12293 C CG  . GLU E 1 207 ? 114.336 150.989 108.593 1.00 55.91  ? 153 GLU E CG  1 
ATOM   12294 C CD  . GLU E 1 207 ? 113.128 151.882 108.799 1.00 64.80  ? 153 GLU E CD  1 
ATOM   12295 O OE1 . GLU E 1 207 ? 112.509 152.296 107.796 1.00 65.06  ? 153 GLU E OE1 1 
ATOM   12296 O OE2 . GLU E 1 207 ? 112.796 152.173 109.968 1.00 69.76  ? 153 GLU E OE2 1 
ATOM   12297 N N   . ILE E 1 208 ? 112.991 149.156 104.432 1.00 42.57  ? 154 ILE E N   1 
ATOM   12298 C CA  . ILE E 1 208 ? 113.117 148.599 103.092 1.00 40.88  ? 154 ILE E CA  1 
ATOM   12299 C C   . ILE E 1 208 ? 113.379 149.744 102.126 1.00 41.70  ? 154 ILE E C   1 
ATOM   12300 O O   . ILE E 1 208 ? 112.635 150.731 102.116 1.00 48.54  ? 154 ILE E O   1 
ATOM   12301 C CB  . ILE E 1 208 ? 111.850 147.825 102.690 1.00 40.32  ? 154 ILE E CB  1 
ATOM   12302 C CG1 . ILE E 1 208 ? 111.508 146.776 103.748 1.00 39.25  ? 154 ILE E CG1 1 
ATOM   12303 C CG2 . ILE E 1 208 ? 112.028 147.183 101.335 1.00 41.41  ? 154 ILE E CG2 1 
ATOM   12304 C CD1 . ILE E 1 208 ? 110.178 146.108 103.528 1.00 35.69  ? 154 ILE E CD1 1 
ATOM   12305 N N   . GLU E 1 209 ? 114.423 149.612 101.311 1.00 38.24  ? 155 GLU E N   1 
ATOM   12306 C CA  . GLU E 1 209 ? 114.821 150.691 100.419 1.00 44.28  ? 155 GLU E CA  1 
ATOM   12307 C C   . GLU E 1 209 ? 115.317 150.113 99.101  1.00 49.08  ? 155 GLU E C   1 
ATOM   12308 O O   . GLU E 1 209 ? 115.594 148.917 98.983  1.00 52.58  ? 155 GLU E O   1 
ATOM   12309 C CB  . GLU E 1 209 ? 115.890 151.575 101.075 1.00 46.71  ? 155 GLU E CB  1 
ATOM   12310 C CG  . GLU E 1 209 ? 116.103 152.916 100.401 1.00 51.60  ? 155 GLU E CG  1 
ATOM   12311 C CD  . GLU E 1 209 ? 116.788 153.914 101.302 1.00 63.65  ? 155 GLU E CD  1 
ATOM   12312 O OE1 . GLU E 1 209 ? 116.533 153.881 102.523 1.00 66.47  ? 155 GLU E OE1 1 
ATOM   12313 O OE2 . GLU E 1 209 ? 117.583 154.729 100.791 1.00 67.41  ? 155 GLU E OE2 1 
ATOM   12314 N N   . SER E 1 210 ? 115.399 150.978 98.091  1.00 45.24  ? 156 SER E N   1 
ATOM   12315 C CA  . SER E 1 210 ? 116.011 150.649 96.811  1.00 42.69  ? 156 SER E CA  1 
ATOM   12316 C C   . SER E 1 210 ? 117.447 151.151 96.826  1.00 48.02  ? 156 SER E C   1 
ATOM   12317 O O   . SER E 1 210 ? 117.689 152.345 97.033  1.00 57.95  ? 156 SER E O   1 
ATOM   12318 C CB  . SER E 1 210 ? 115.238 151.273 95.651  1.00 44.63  ? 156 SER E CB  1 
ATOM   12319 O OG  . SER E 1 210 ? 115.860 150.974 94.415  1.00 51.35  ? 156 SER E OG  1 
ATOM   12320 N N   . TYR E 1 211 ? 118.395 150.241 96.605  1.00 41.99  ? 157 TYR E N   1 
ATOM   12321 C CA  . TYR E 1 211 ? 119.799 150.578 96.808  1.00 44.39  ? 157 TYR E CA  1 
ATOM   12322 C C   . TYR E 1 211 ? 120.302 151.565 95.762  1.00 49.93  ? 157 TYR E C   1 
ATOM   12323 O O   . TYR E 1 211 ? 120.940 152.568 96.100  1.00 57.57  ? 157 TYR E O   1 
ATOM   12324 C CB  . TYR E 1 211 ? 120.649 149.308 96.801  1.00 43.08  ? 157 TYR E CB  1 
ATOM   12325 C CG  . TYR E 1 211 ? 122.068 149.553 97.248  1.00 45.40  ? 157 TYR E CG  1 
ATOM   12326 C CD1 . TYR E 1 211 ? 122.401 149.543 98.593  1.00 45.34  ? 157 TYR E CD1 1 
ATOM   12327 C CD2 . TYR E 1 211 ? 123.071 149.808 96.326  1.00 47.42  ? 157 TYR E CD2 1 
ATOM   12328 C CE1 . TYR E 1 211 ? 123.694 149.773 99.006  1.00 47.55  ? 157 TYR E CE1 1 
ATOM   12329 C CE2 . TYR E 1 211 ? 124.365 150.039 96.731  1.00 52.10  ? 157 TYR E CE2 1 
ATOM   12330 C CZ  . TYR E 1 211 ? 124.670 150.022 98.071  1.00 53.74  ? 157 TYR E CZ  1 
ATOM   12331 O OH  . TYR E 1 211 ? 125.959 150.251 98.479  1.00 56.84  ? 157 TYR E OH  1 
ATOM   12332 N N   . GLY E 1 212 ? 120.031 151.302 94.486  1.00 47.94  ? 158 GLY E N   1 
ATOM   12333 C CA  . GLY E 1 212 ? 120.649 152.086 93.435  1.00 48.06  ? 158 GLY E CA  1 
ATOM   12334 C C   . GLY E 1 212 ? 119.728 152.982 92.633  1.00 51.31  ? 158 GLY E C   1 
ATOM   12335 O O   . GLY E 1 212 ? 120.203 153.824 91.867  1.00 54.33  ? 158 GLY E O   1 
ATOM   12336 N N   . TYR E 1 213 ? 118.419 152.829 92.796  1.00 51.07  ? 159 TYR E N   1 
ATOM   12337 C CA  . TYR E 1 213 ? 117.450 153.595 92.024  1.00 48.50  ? 159 TYR E CA  1 
ATOM   12338 C C   . TYR E 1 213 ? 116.823 154.674 92.894  1.00 52.04  ? 159 TYR E C   1 
ATOM   12339 O O   . TYR E 1 213 ? 116.415 154.405 94.028  1.00 56.96  ? 159 TYR E O   1 
ATOM   12340 C CB  . TYR E 1 213 ? 116.363 152.684 91.453  1.00 45.76  ? 159 TYR E CB  1 
ATOM   12341 C CG  . TYR E 1 213 ? 116.875 151.698 90.432  1.00 46.16  ? 159 TYR E CG  1 
ATOM   12342 C CD1 . TYR E 1 213 ? 117.101 152.084 89.119  1.00 52.02  ? 159 TYR E CD1 1 
ATOM   12343 C CD2 . TYR E 1 213 ? 117.132 150.383 90.781  1.00 43.22  ? 159 TYR E CD2 1 
ATOM   12344 C CE1 . TYR E 1 213 ? 117.570 151.186 88.185  1.00 53.76  ? 159 TYR E CE1 1 
ATOM   12345 C CE2 . TYR E 1 213 ? 117.601 149.479 89.854  1.00 46.54  ? 159 TYR E CE2 1 
ATOM   12346 C CZ  . TYR E 1 213 ? 117.817 149.884 88.558  1.00 50.08  ? 159 TYR E CZ  1 
ATOM   12347 O OH  . TYR E 1 213 ? 118.285 148.981 87.632  1.00 51.92  ? 159 TYR E OH  1 
ATOM   12348 N N   . THR E 1 214 ? 116.745 155.888 92.358  1.00 53.98  ? 160 THR E N   1 
ATOM   12349 C CA  . THR E 1 214 ? 116.116 156.999 93.049  1.00 57.07  ? 160 THR E CA  1 
ATOM   12350 C C   . THR E 1 214 ? 114.619 157.012 92.749  1.00 59.81  ? 160 THR E C   1 
ATOM   12351 O O   . THR E 1 214 ? 114.100 156.172 92.010  1.00 65.22  ? 160 THR E O   1 
ATOM   12352 C CB  . THR E 1 214 ? 116.768 158.320 92.649  1.00 58.37  ? 160 THR E CB  1 
ATOM   12353 O OG1 . THR E 1 214 ? 116.605 158.527 91.240  1.00 63.76  ? 160 THR E OG1 1 
ATOM   12354 C CG2 . THR E 1 214 ? 118.248 158.307 92.985  1.00 61.76  ? 160 THR E CG2 1 
ATOM   12355 N N   . THR E 1 215 ? 113.909 157.981 93.331  1.00 57.82  ? 161 THR E N   1 
ATOM   12356 C CA  . THR E 1 215 ? 112.470 158.076 93.117  1.00 62.26  ? 161 THR E CA  1 
ATOM   12357 C C   . THR E 1 215 ? 112.106 158.431 91.683  1.00 69.68  ? 161 THR E C   1 
ATOM   12358 O O   . THR E 1 215 ? 110.937 158.293 91.309  1.00 74.49  ? 161 THR E O   1 
ATOM   12359 C CB  . THR E 1 215 ? 111.857 159.106 94.066  1.00 69.67  ? 161 THR E CB  1 
ATOM   12360 O OG1 . THR E 1 215 ? 112.581 160.339 93.971  1.00 75.04  ? 161 THR E OG1 1 
ATOM   12361 C CG2 . THR E 1 215 ? 111.902 158.601 95.494  1.00 64.79  ? 161 THR E CG2 1 
ATOM   12362 N N   . ASP E 1 216 ? 113.066 158.888 90.879  1.00 68.61  ? 162 ASP E N   1 
ATOM   12363 C CA  . ASP E 1 216 ? 112.812 159.058 89.455  1.00 73.14  ? 162 ASP E CA  1 
ATOM   12364 C C   . ASP E 1 216 ? 112.659 157.724 88.741  1.00 68.64  ? 162 ASP E C   1 
ATOM   12365 O O   . ASP E 1 216 ? 112.039 157.674 87.674  1.00 67.83  ? 162 ASP E O   1 
ATOM   12366 C CB  . ASP E 1 216 ? 113.938 159.864 88.807  1.00 79.68  ? 162 ASP E CB  1 
ATOM   12367 C CG  . ASP E 1 216 ? 114.007 161.285 89.322  1.00 89.62  ? 162 ASP E CG  1 
ATOM   12368 O OD1 . ASP E 1 216 ? 112.951 161.830 89.705  1.00 88.69  ? 162 ASP E OD1 1 
ATOM   12369 O OD2 . ASP E 1 216 ? 115.117 161.858 89.344  1.00 96.00  ? 162 ASP E OD2 1 
ATOM   12370 N N   . ASP E 1 217 ? 113.202 156.649 89.304  1.00 65.63  ? 163 ASP E N   1 
ATOM   12371 C CA  . ASP E 1 217 ? 113.240 155.347 88.650  1.00 59.71  ? 163 ASP E CA  1 
ATOM   12372 C C   . ASP E 1 217 ? 112.308 154.319 89.268  1.00 60.28  ? 163 ASP E C   1 
ATOM   12373 O O   . ASP E 1 217 ? 111.737 153.505 88.540  1.00 63.63  ? 163 ASP E O   1 
ATOM   12374 C CB  . ASP E 1 217 ? 114.668 154.794 88.663  1.00 55.64  ? 163 ASP E CB  1 
ATOM   12375 C CG  . ASP E 1 217 ? 115.628 155.647 87.864  1.00 65.14  ? 163 ASP E CG  1 
ATOM   12376 O OD1 . ASP E 1 217 ? 115.221 156.737 87.413  1.00 72.51  ? 163 ASP E OD1 1 
ATOM   12377 O OD2 . ASP E 1 217 ? 116.789 155.226 87.683  1.00 68.28  ? 163 ASP E OD2 1 
ATOM   12378 N N   . ILE E 1 218 ? 112.142 154.317 90.587  1.00 59.62  ? 164 ILE E N   1 
ATOM   12379 C CA  . ILE E 1 218 ? 111.365 153.283 91.256  1.00 51.64  ? 164 ILE E CA  1 
ATOM   12380 C C   . ILE E 1 218 ? 110.554 153.904 92.386  1.00 50.97  ? 164 ILE E C   1 
ATOM   12381 O O   . ILE E 1 218 ? 110.945 154.914 92.977  1.00 52.53  ? 164 ILE E O   1 
ATOM   12382 C CB  . ILE E 1 218 ? 112.275 152.146 91.773  1.00 44.02  ? 164 ILE E CB  1 
ATOM   12383 C CG1 . ILE E 1 218 ? 111.506 150.827 91.831  1.00 51.63  ? 164 ILE E CG1 1 
ATOM   12384 C CG2 . ILE E 1 218 ? 112.855 152.487 93.135  1.00 44.99  ? 164 ILE E CG2 1 
ATOM   12385 C CD1 . ILE E 1 218 ? 112.377 149.639 92.159  1.00 55.18  ? 164 ILE E CD1 1 
ATOM   12386 N N   . GLU E 1 219 ? 109.399 153.304 92.660  1.00 49.73  ? 165 GLU E N   1 
ATOM   12387 C CA  . GLU E 1 219 ? 108.525 153.735 93.741  1.00 51.17  ? 165 GLU E CA  1 
ATOM   12388 C C   . GLU E 1 219 ? 108.009 152.516 94.489  1.00 51.22  ? 165 GLU E C   1 
ATOM   12389 O O   . GLU E 1 219 ? 107.599 151.530 93.872  1.00 55.59  ? 165 GLU E O   1 
ATOM   12390 C CB  . GLU E 1 219 ? 107.344 154.558 93.219  1.00 52.64  ? 165 GLU E CB  1 
ATOM   12391 C CG  . GLU E 1 219 ? 107.722 155.923 92.682  1.00 65.73  ? 165 GLU E CG  1 
ATOM   12392 C CD  . GLU E 1 219 ? 106.508 156.759 92.341  1.00 81.45  ? 165 GLU E CD  1 
ATOM   12393 O OE1 . GLU E 1 219 ? 105.379 156.256 92.514  1.00 83.47  ? 165 GLU E OE1 1 
ATOM   12394 O OE2 . GLU E 1 219 ? 106.680 157.916 91.904  1.00 85.49  ? 165 GLU E OE2 1 
ATOM   12395 N N   . PHE E 1 220 ? 108.032 152.591 95.815  1.00 42.59  ? 166 PHE E N   1 
ATOM   12396 C CA  . PHE E 1 220 ? 107.563 151.512 96.670  1.00 38.12  ? 166 PHE E CA  1 
ATOM   12397 C C   . PHE E 1 220 ? 106.209 151.863 97.269  1.00 38.42  ? 166 PHE E C   1 
ATOM   12398 O O   . PHE E 1 220 ? 105.933 153.022 97.590  1.00 46.38  ? 166 PHE E O   1 
ATOM   12399 C CB  . PHE E 1 220 ? 108.548 151.225 97.805  1.00 41.66  ? 166 PHE E CB  1 
ATOM   12400 C CG  . PHE E 1 220 ? 109.864 150.670 97.350  1.00 40.73  ? 166 PHE E CG  1 
ATOM   12401 C CD1 . PHE E 1 220 ? 110.050 150.255 96.044  1.00 40.81  ? 166 PHE E CD1 1 
ATOM   12402 C CD2 . PHE E 1 220 ? 110.916 150.555 98.239  1.00 41.74  ? 166 PHE E CD2 1 
ATOM   12403 C CE1 . PHE E 1 220 ? 111.261 149.747 95.633  1.00 41.08  ? 166 PHE E CE1 1 
ATOM   12404 C CE2 . PHE E 1 220 ? 112.127 150.045 97.835  1.00 43.45  ? 166 PHE E CE2 1 
ATOM   12405 C CZ  . PHE E 1 220 ? 112.300 149.640 96.531  1.00 43.53  ? 166 PHE E CZ  1 
ATOM   12406 N N   . TYR E 1 221 ? 105.367 150.846 97.424  1.00 36.11  ? 167 TYR E N   1 
ATOM   12407 C CA  . TYR E 1 221 ? 104.118 151.008 98.148  1.00 39.38  ? 167 TYR E CA  1 
ATOM   12408 C C   . TYR E 1 221 ? 103.726 149.668 98.748  1.00 43.31  ? 167 TYR E C   1 
ATOM   12409 O O   . TYR E 1 221 ? 104.146 148.608 98.278  1.00 43.45  ? 167 TYR E O   1 
ATOM   12410 C CB  . TYR E 1 221 ? 103.003 151.562 97.250  1.00 35.30  ? 167 TYR E CB  1 
ATOM   12411 C CG  . TYR E 1 221 ? 102.505 150.613 96.184  1.00 36.10  ? 167 TYR E CG  1 
ATOM   12412 C CD1 . TYR E 1 221 ? 103.073 150.595 94.919  1.00 40.33  ? 167 TYR E CD1 1 
ATOM   12413 C CD2 . TYR E 1 221 ? 101.448 149.750 96.437  1.00 38.09  ? 167 TYR E CD2 1 
ATOM   12414 C CE1 . TYR E 1 221 ? 102.611 149.734 93.941  1.00 46.51  ? 167 TYR E CE1 1 
ATOM   12415 C CE2 . TYR E 1 221 ? 100.983 148.886 95.468  1.00 45.83  ? 167 TYR E CE2 1 
ATOM   12416 C CZ  . TYR E 1 221 ? 101.566 148.882 94.223  1.00 49.30  ? 167 TYR E CZ  1 
ATOM   12417 O OH  . TYR E 1 221 ? 101.100 148.021 93.257  1.00 48.80  ? 167 TYR E OH  1 
ATOM   12418 N N   . TRP E 1 222 ? 102.917 149.727 99.802  1.00 44.85  ? 168 TRP E N   1 
ATOM   12419 C CA  . TRP E 1 222 ? 102.409 148.521 100.445 1.00 43.37  ? 168 TRP E CA  1 
ATOM   12420 C C   . TRP E 1 222 ? 101.183 148.044 99.679  1.00 45.61  ? 168 TRP E C   1 
ATOM   12421 O O   . TRP E 1 222 ? 100.116 148.660 99.753  1.00 51.00  ? 168 TRP E O   1 
ATOM   12422 C CB  . TRP E 1 222 ? 102.074 148.791 101.909 1.00 44.74  ? 168 TRP E CB  1 
ATOM   12423 C CG  . TRP E 1 222 ? 103.272 149.005 102.773 1.00 44.15  ? 168 TRP E CG  1 
ATOM   12424 C CD1 . TRP E 1 222 ? 103.688 150.182 103.317 1.00 47.21  ? 168 TRP E CD1 1 
ATOM   12425 C CD2 . TRP E 1 222 ? 104.215 148.013 103.192 1.00 43.18  ? 168 TRP E CD2 1 
ATOM   12426 N NE1 . TRP E 1 222 ? 104.831 149.986 104.053 1.00 49.73  ? 168 TRP E NE1 1 
ATOM   12427 C CE2 . TRP E 1 222 ? 105.176 148.662 103.991 1.00 45.93  ? 168 TRP E CE2 1 
ATOM   12428 C CE3 . TRP E 1 222 ? 104.341 146.639 102.969 1.00 41.65  ? 168 TRP E CE3 1 
ATOM   12429 C CZ2 . TRP E 1 222 ? 106.246 147.985 104.568 1.00 40.22  ? 168 TRP E CZ2 1 
ATOM   12430 C CZ3 . TRP E 1 222 ? 105.402 145.970 103.542 1.00 38.64  ? 168 TRP E CZ3 1 
ATOM   12431 C CH2 . TRP E 1 222 ? 106.341 146.642 104.332 1.00 36.46  ? 168 TRP E CH2 1 
ATOM   12432 N N   . ARG E 1 223 ? 101.330 146.944 98.949  1.00 41.51  ? 169 ARG E N   1 
ATOM   12433 C CA  . ARG E 1 223 ? 100.257 146.427 98.105  1.00 41.25  ? 169 ARG E CA  1 
ATOM   12434 C C   . ARG E 1 223 ? 99.175  145.828 98.991  1.00 40.43  ? 169 ARG E C   1 
ATOM   12435 O O   . ARG E 1 223 ? 99.306  144.705 99.481  1.00 39.50  ? 169 ARG E O   1 
ATOM   12436 C CB  . ARG E 1 223 ? 100.806 145.399 97.124  1.00 42.22  ? 169 ARG E CB  1 
ATOM   12437 C CG  . ARG E 1 223 ? 99.778  144.837 96.172  1.00 44.94  ? 169 ARG E CG  1 
ATOM   12438 C CD  . ARG E 1 223 ? 100.443 143.946 95.145  1.00 51.01  ? 169 ARG E CD  1 
ATOM   12439 N NE  . ARG E 1 223 ? 99.479  143.347 94.230  1.00 68.26  ? 169 ARG E NE  1 
ATOM   12440 C CZ  . ARG E 1 223 ? 98.929  142.154 94.402  1.00 71.94  ? 169 ARG E CZ  1 
ATOM   12441 N NH1 . ARG E 1 223 ? 99.221  141.403 95.451  1.00 64.65  ? 169 ARG E NH1 1 
ATOM   12442 N NH2 . ARG E 1 223 ? 98.067  141.700 93.496  1.00 73.72  ? 169 ARG E NH2 1 
ATOM   12443 N N   . GLY E 1 224 ? 98.097  146.578 99.194  1.00 42.85  ? 170 GLY E N   1 
ATOM   12444 C CA  . GLY E 1 224 ? 97.018  146.174 100.079 1.00 47.11  ? 170 GLY E CA  1 
ATOM   12445 C C   . GLY E 1 224 ? 96.800  147.087 101.268 1.00 52.68  ? 170 GLY E C   1 
ATOM   12446 O O   . GLY E 1 224 ? 95.900  146.815 102.075 1.00 55.54  ? 170 GLY E O   1 
ATOM   12447 N N   . GLY E 1 225 ? 97.573  148.159 101.421 1.00 51.61  ? 171 GLY E N   1 
ATOM   12448 C CA  . GLY E 1 225 ? 97.349  149.068 102.532 1.00 52.47  ? 171 GLY E CA  1 
ATOM   12449 C C   . GLY E 1 225 ? 97.829  148.478 103.843 1.00 57.00  ? 171 GLY E C   1 
ATOM   12450 O O   . GLY E 1 225 ? 98.901  147.870 103.928 1.00 59.55  ? 171 GLY E O   1 
ATOM   12451 N N   . ASP E 1 226 ? 97.021  148.664 104.888 1.00 63.82  ? 172 ASP E N   1 
ATOM   12452 C CA  . ASP E 1 226 ? 97.365  148.151 106.209 1.00 62.72  ? 172 ASP E CA  1 
ATOM   12453 C C   . ASP E 1 226 ? 97.375  146.628 106.260 1.00 63.71  ? 172 ASP E C   1 
ATOM   12454 O O   . ASP E 1 226 ? 97.927  146.057 107.206 1.00 60.79  ? 172 ASP E O   1 
ATOM   12455 C CB  . ASP E 1 226 ? 96.391  148.705 107.250 1.00 72.10  ? 172 ASP E CB  1 
ATOM   12456 C CG  . ASP E 1 226 ? 96.350  150.223 107.259 1.00 84.01  ? 172 ASP E CG  1 
ATOM   12457 O OD1 . ASP E 1 226 ? 97.132  150.844 106.508 1.00 85.06  ? 172 ASP E OD1 1 
ATOM   12458 O OD2 . ASP E 1 226 ? 95.536  150.795 108.015 1.00 87.29  ? 172 ASP E OD2 1 
ATOM   12459 N N   . LYS E 1 227 ? 96.784  145.962 105.270 1.00 58.60  ? 173 LYS E N   1 
ATOM   12460 C CA  . LYS E 1 227 ? 96.766  144.508 105.197 1.00 54.40  ? 173 LYS E CA  1 
ATOM   12461 C C   . LYS E 1 227 ? 97.959  143.941 104.439 1.00 54.78  ? 173 LYS E C   1 
ATOM   12462 O O   . LYS E 1 227 ? 97.985  142.738 104.161 1.00 60.05  ? 173 LYS E O   1 
ATOM   12463 C CB  . LYS E 1 227 ? 95.470  144.029 104.542 1.00 57.26  ? 173 LYS E CB  1 
ATOM   12464 C CG  . LYS E 1 227 ? 94.214  144.336 105.334 1.00 65.48  ? 173 LYS E CG  1 
ATOM   12465 C CD  . LYS E 1 227 ? 92.983  143.832 104.604 1.00 72.34  ? 173 LYS E CD  1 
ATOM   12466 C CE  . LYS E 1 227 ? 91.716  144.101 105.395 1.00 74.60  ? 173 LYS E CE  1 
ATOM   12467 N NZ  . LYS E 1 227 ? 90.509  143.638 104.659 1.00 73.29  ? 173 LYS E NZ  1 
ATOM   12468 N N   . ALA E 1 228 ? 98.938  144.779 104.090 1.00 51.78  ? 174 ALA E N   1 
ATOM   12469 C CA  . ALA E 1 228 ? 100.073 144.307 103.303 1.00 47.70  ? 174 ALA E CA  1 
ATOM   12470 C C   . ALA E 1 228 ? 100.892 143.274 104.065 1.00 45.03  ? 174 ALA E C   1 
ATOM   12471 O O   . ALA E 1 228 ? 101.342 142.280 103.485 1.00 49.22  ? 174 ALA E O   1 
ATOM   12472 C CB  . ALA E 1 228 ? 100.950 145.487 102.892 1.00 43.51  ? 174 ALA E CB  1 
ATOM   12473 N N   . VAL E 1 229 ? 101.097 143.488 105.360 1.00 41.60  ? 175 VAL E N   1 
ATOM   12474 C CA  . VAL E 1 229 ? 101.872 142.577 106.192 1.00 42.14  ? 175 VAL E CA  1 
ATOM   12475 C C   . VAL E 1 229 ? 100.905 141.700 106.973 1.00 45.22  ? 175 VAL E C   1 
ATOM   12476 O O   . VAL E 1 229 ? 100.048 142.207 107.706 1.00 51.83  ? 175 VAL E O   1 
ATOM   12477 C CB  . VAL E 1 229 ? 102.817 143.336 107.135 1.00 42.50  ? 175 VAL E CB  1 
ATOM   12478 C CG1 . VAL E 1 229 ? 103.505 142.369 108.076 1.00 40.94  ? 175 VAL E CG1 1 
ATOM   12479 C CG2 . VAL E 1 229 ? 103.846 144.109 106.332 1.00 43.66  ? 175 VAL E CG2 1 
ATOM   12480 N N   . THR E 1 230 ? 101.042 140.387 106.818 1.00 45.14  ? 176 THR E N   1 
ATOM   12481 C CA  . THR E 1 230 ? 100.155 139.420 107.441 1.00 51.92  ? 176 THR E CA  1 
ATOM   12482 C C   . THR E 1 230 ? 100.947 138.492 108.352 1.00 55.38  ? 176 THR E C   1 
ATOM   12483 O O   . THR E 1 230 ? 102.175 138.407 108.272 1.00 53.26  ? 176 THR E O   1 
ATOM   12484 C CB  . THR E 1 230 ? 99.404  138.597 106.386 1.00 54.51  ? 176 THR E CB  1 
ATOM   12485 O OG1 . THR E 1 230 ? 100.345 137.885 105.574 1.00 52.14  ? 176 THR E OG1 1 
ATOM   12486 C CG2 . THR E 1 230 ? 98.567  139.506 105.500 1.00 51.66  ? 176 THR E CG2 1 
ATOM   12487 N N   . GLY E 1 231 ? 100.225 137.798 109.229 1.00 58.06  ? 177 GLY E N   1 
ATOM   12488 C CA  . GLY E 1 231 ? 100.843 136.861 110.143 1.00 63.08  ? 177 GLY E CA  1 
ATOM   12489 C C   . GLY E 1 231 ? 101.439 137.465 111.392 1.00 65.82  ? 177 GLY E C   1 
ATOM   12490 O O   . GLY E 1 231 ? 102.085 136.742 112.160 1.00 65.52  ? 177 GLY E O   1 
ATOM   12491 N N   . VAL E 1 232 ? 101.247 138.764 111.627 1.00 66.57  ? 178 VAL E N   1 
ATOM   12492 C CA  . VAL E 1 232 ? 101.811 139.387 112.820 1.00 64.05  ? 178 VAL E CA  1 
ATOM   12493 C C   . VAL E 1 232 ? 101.116 138.871 114.073 1.00 66.67  ? 178 VAL E C   1 
ATOM   12494 O O   . VAL E 1 232 ? 101.752 138.676 115.116 1.00 66.73  ? 178 VAL E O   1 
ATOM   12495 C CB  . VAL E 1 232 ? 101.727 140.920 112.715 1.00 62.83  ? 178 VAL E CB  1 
ATOM   12496 C CG1 . VAL E 1 232 ? 102.450 141.572 113.883 1.00 64.15  ? 178 VAL E CG1 1 
ATOM   12497 C CG2 . VAL E 1 232 ? 102.313 141.388 111.397 1.00 59.20  ? 178 VAL E CG2 1 
ATOM   12498 N N   . GLU E 1 233 ? 99.803  138.644 113.997 1.00 72.66  ? 179 GLU E N   1 
ATOM   12499 C CA  . GLU E 1 233 ? 99.054  138.191 115.164 1.00 80.56  ? 179 GLU E CA  1 
ATOM   12500 C C   . GLU E 1 233 ? 99.427  136.775 115.586 1.00 80.53  ? 179 GLU E C   1 
ATOM   12501 O O   . GLU E 1 233 ? 99.142  136.388 116.724 1.00 80.43  ? 179 GLU E O   1 
ATOM   12502 C CB  . GLU E 1 233 ? 97.549  138.272 114.892 1.00 79.29  ? 179 GLU E CB  1 
ATOM   12503 C CG  . GLU E 1 233 ? 96.932  137.006 114.306 1.00 88.21  ? 179 GLU E CG  1 
ATOM   12504 C CD  . GLU E 1 233 ? 97.266  136.797 112.840 1.00 87.14  ? 179 GLU E CD  1 
ATOM   12505 O OE1 . GLU E 1 233 ? 98.024  137.609 112.271 1.00 86.30  ? 179 GLU E OE1 1 
ATOM   12506 O OE2 . GLU E 1 233 ? 96.762  135.817 112.251 1.00 87.51  ? 179 GLU E OE2 1 
ATOM   12507 N N   . ARG E 1 234 ? 100.051 135.998 114.705 1.00 78.36  ? 180 ARG E N   1 
ATOM   12508 C CA  . ARG E 1 234 ? 100.434 134.627 115.010 1.00 78.46  ? 180 ARG E CA  1 
ATOM   12509 C C   . ARG E 1 234 ? 101.851 134.510 115.555 1.00 86.15  ? 180 ARG E C   1 
ATOM   12510 O O   . ARG E 1 234 ? 102.293 133.395 115.851 1.00 90.66  ? 180 ARG E O   1 
ATOM   12511 C CB  . ARG E 1 234 ? 100.284 133.749 113.763 1.00 81.38  ? 180 ARG E CB  1 
ATOM   12512 C CG  . ARG E 1 234 ? 98.839  133.522 113.346 1.00 86.75  ? 180 ARG E CG  1 
ATOM   12513 C CD  . ARG E 1 234 ? 98.718  132.564 112.166 1.00 90.94  ? 180 ARG E CD  1 
ATOM   12514 N NE  . ARG E 1 234 ? 99.031  133.196 110.890 1.00 94.91  ? 180 ARG E NE  1 
ATOM   12515 C CZ  . ARG E 1 234 ? 100.163 133.021 110.221 1.00 95.90  ? 180 ARG E CZ  1 
ATOM   12516 N NH1 . ARG E 1 234 ? 101.124 132.237 110.682 1.00 90.49  ? 180 ARG E NH1 1 
ATOM   12517 N NH2 . ARG E 1 234 ? 100.334 133.645 109.059 1.00 87.83  ? 180 ARG E NH2 1 
ATOM   12518 N N   . ILE E 1 235 ? 102.571 135.623 115.693 1.00 85.66  ? 181 ILE E N   1 
ATOM   12519 C CA  . ILE E 1 235 ? 103.933 135.579 116.212 1.00 83.57  ? 181 ILE E CA  1 
ATOM   12520 C C   . ILE E 1 235 ? 103.901 135.229 117.692 1.00 90.02  ? 181 ILE E C   1 
ATOM   12521 O O   . ILE E 1 235 ? 103.151 135.828 118.474 1.00 88.16  ? 181 ILE E O   1 
ATOM   12522 C CB  . ILE E 1 235 ? 104.646 136.917 115.973 1.00 76.52  ? 181 ILE E CB  1 
ATOM   12523 C CG1 . ILE E 1 235 ? 104.697 137.236 114.479 1.00 71.31  ? 181 ILE E CG1 1 
ATOM   12524 C CG2 . ILE E 1 235 ? 106.048 136.884 116.556 1.00 68.84  ? 181 ILE E CG2 1 
ATOM   12525 C CD1 . ILE E 1 235 ? 105.363 138.556 114.167 1.00 62.51  ? 181 ILE E CD1 1 
ATOM   12526 N N   . GLU E 1 236 ? 104.720 134.259 118.086 1.00 95.56  ? 182 GLU E N   1 
ATOM   12527 C CA  . GLU E 1 236 ? 104.778 133.770 119.460 1.00 94.06  ? 182 GLU E CA  1 
ATOM   12528 C C   . GLU E 1 236 ? 106.158 134.102 120.021 1.00 89.83  ? 182 GLU E C   1 
ATOM   12529 O O   . GLU E 1 236 ? 107.077 133.283 119.976 1.00 92.83  ? 182 GLU E O   1 
ATOM   12530 C CB  . GLU E 1 236 ? 104.502 132.272 119.508 1.00 102.51 ? 182 GLU E CB  1 
ATOM   12531 C CG  . GLU E 1 236 ? 103.330 131.839 118.646 1.00 107.58 ? 182 GLU E CG  1 
ATOM   12532 C CD  . GLU E 1 236 ? 103.606 130.551 117.894 1.00 119.97 ? 182 GLU E CD  1 
ATOM   12533 O OE1 . GLU E 1 236 ? 104.579 129.851 118.245 1.00 124.61 ? 182 GLU E OE1 1 
ATOM   12534 O OE2 . GLU E 1 236 ? 102.853 130.243 116.946 1.00 122.99 ? 182 GLU E OE2 1 
ATOM   12535 N N   . LEU E 1 237 ? 106.297 135.309 120.553 1.00 79.81  ? 183 LEU E N   1 
ATOM   12536 C CA  . LEU E 1 237 ? 107.557 135.702 121.171 1.00 76.60  ? 183 LEU E CA  1 
ATOM   12537 C C   . LEU E 1 237 ? 107.629 135.155 122.592 1.00 78.28  ? 183 LEU E C   1 
ATOM   12538 O O   . LEU E 1 237 ? 106.699 135.365 123.377 1.00 77.13  ? 183 LEU E O   1 
ATOM   12539 C CB  . LEU E 1 237 ? 107.709 137.218 121.181 1.00 72.81  ? 183 LEU E CB  1 
ATOM   12540 C CG  . LEU E 1 237 ? 108.463 137.802 119.986 1.00 67.66  ? 183 LEU E CG  1 
ATOM   12541 C CD1 . LEU E 1 237 ? 108.601 139.308 120.118 1.00 63.53  ? 183 LEU E CD1 1 
ATOM   12542 C CD2 . LEU E 1 237 ? 109.828 137.147 119.855 1.00 63.30  ? 183 LEU E CD2 1 
ATOM   12543 N N   . PRO E 1 238 ? 108.699 134.441 122.948 1.00 80.93  ? 184 PRO E N   1 
ATOM   12544 C CA  . PRO E 1 238 ? 108.783 133.882 124.309 1.00 78.80  ? 184 PRO E CA  1 
ATOM   12545 C C   . PRO E 1 238 ? 108.705 134.929 125.405 1.00 76.13  ? 184 PRO E C   1 
ATOM   12546 O O   . PRO E 1 238 ? 108.068 134.690 126.437 1.00 75.21  ? 184 PRO E O   1 
ATOM   12547 C CB  . PRO E 1 238 ? 110.141 133.165 124.305 1.00 83.08  ? 184 PRO E CB  1 
ATOM   12548 C CG  . PRO E 1 238 ? 110.440 132.912 122.859 1.00 84.62  ? 184 PRO E CG  1 
ATOM   12549 C CD  . PRO E 1 238 ? 109.862 134.077 122.122 1.00 80.94  ? 184 PRO E CD  1 
ATOM   12550 N N   . GLN E 1 239 ? 109.325 136.090 125.209 1.00 77.11  ? 185 GLN E N   1 
ATOM   12551 C CA  . GLN E 1 239 ? 109.378 137.122 126.236 1.00 76.95  ? 185 GLN E CA  1 
ATOM   12552 C C   . GLN E 1 239 ? 108.445 138.289 125.956 1.00 74.51  ? 185 GLN E C   1 
ATOM   12553 O O   . GLN E 1 239 ? 107.619 138.636 126.804 1.00 70.36  ? 185 GLN E O   1 
ATOM   12554 C CB  . GLN E 1 239 ? 110.816 137.635 126.389 1.00 78.29  ? 185 GLN E CB  1 
ATOM   12555 C CG  . GLN E 1 239 ? 110.969 138.714 127.444 1.00 84.57  ? 185 GLN E CG  1 
ATOM   12556 C CD  . GLN E 1 239 ? 112.368 139.291 127.489 1.00 91.00  ? 185 GLN E CD  1 
ATOM   12557 O OE1 . GLN E 1 239 ? 112.692 140.098 128.361 1.00 93.83  ? 185 GLN E OE1 1 
ATOM   12558 N NE2 . GLN E 1 239 ? 113.207 138.883 126.544 1.00 85.86  ? 185 GLN E NE2 1 
ATOM   12559 N N   . PHE E 1 240 ? 108.556 138.908 124.786 1.00 75.90  ? 186 PHE E N   1 
ATOM   12560 C CA  . PHE E 1 240 ? 107.747 140.074 124.475 1.00 72.17  ? 186 PHE E CA  1 
ATOM   12561 C C   . PHE E 1 240 ? 106.349 139.662 124.022 1.00 70.10  ? 186 PHE E C   1 
ATOM   12562 O O   . PHE E 1 240 ? 106.068 138.493 123.744 1.00 72.45  ? 186 PHE E O   1 
ATOM   12563 C CB  . PHE E 1 240 ? 108.412 140.919 123.393 1.00 67.69  ? 186 PHE E CB  1 
ATOM   12564 C CG  . PHE E 1 240 ? 109.731 141.497 123.798 1.00 70.92  ? 186 PHE E CG  1 
ATOM   12565 C CD1 . PHE E 1 240 ? 110.899 140.776 123.627 1.00 72.53  ? 186 PHE E CD1 1 
ATOM   12566 C CD2 . PHE E 1 240 ? 109.805 142.767 124.341 1.00 71.50  ? 186 PHE E CD2 1 
ATOM   12567 C CE1 . PHE E 1 240 ? 112.115 141.308 123.996 1.00 74.69  ? 186 PHE E CE1 1 
ATOM   12568 C CE2 . PHE E 1 240 ? 111.018 143.304 124.712 1.00 76.59  ? 186 PHE E CE2 1 
ATOM   12569 C CZ  . PHE E 1 240 ? 112.174 142.574 124.538 1.00 78.81  ? 186 PHE E CZ  1 
ATOM   12570 N N   . SER E 1 241 ? 105.465 140.652 123.960 1.00 66.59  ? 187 SER E N   1 
ATOM   12571 C CA  . SER E 1 241 ? 104.142 140.503 123.374 1.00 69.13  ? 187 SER E CA  1 
ATOM   12572 C C   . SER E 1 241 ? 103.934 141.646 122.395 1.00 71.88  ? 187 SER E C   1 
ATOM   12573 O O   . SER E 1 241 ? 104.107 142.814 122.758 1.00 74.32  ? 187 SER E O   1 
ATOM   12574 C CB  . SER E 1 241 ? 103.050 140.506 124.448 1.00 67.16  ? 187 SER E CB  1 
ATOM   12575 O OG  . SER E 1 241 ? 103.024 141.738 125.148 1.00 76.89  ? 187 SER E OG  1 
ATOM   12576 N N   . ILE E 1 242 ? 103.563 141.314 121.163 1.00 68.39  ? 188 ILE E N   1 
ATOM   12577 C CA  . ILE E 1 242 ? 103.438 142.317 120.111 1.00 67.16  ? 188 ILE E CA  1 
ATOM   12578 C C   . ILE E 1 242 ? 102.112 143.047 120.281 1.00 73.09  ? 188 ILE E C   1 
ATOM   12579 O O   . ILE E 1 242 ? 101.044 142.427 120.276 1.00 75.73  ? 188 ILE E O   1 
ATOM   12580 C CB  . ILE E 1 242 ? 103.546 141.678 118.721 1.00 60.29  ? 188 ILE E CB  1 
ATOM   12581 C CG1 . ILE E 1 242 ? 104.895 140.979 118.569 1.00 62.38  ? 188 ILE E CG1 1 
ATOM   12582 C CG2 . ILE E 1 242 ? 103.359 142.728 117.640 1.00 60.32  ? 188 ILE E CG2 1 
ATOM   12583 C CD1 . ILE E 1 242 ? 105.186 140.518 117.166 1.00 62.56  ? 188 ILE E CD1 1 
ATOM   12584 N N   . VAL E 1 243 ? 102.181 144.366 120.425 1.00 72.91  ? 189 VAL E N   1 
ATOM   12585 C CA  . VAL E 1 243 ? 100.994 145.174 120.675 1.00 70.18  ? 189 VAL E CA  1 
ATOM   12586 C C   . VAL E 1 243 ? 100.432 145.751 119.385 1.00 78.17  ? 189 VAL E C   1 
ATOM   12587 O O   . VAL E 1 243 ? 99.241  145.615 119.096 1.00 89.27  ? 189 VAL E O   1 
ATOM   12588 C CB  . VAL E 1 243 ? 101.325 146.287 121.692 1.00 67.69  ? 189 VAL E CB  1 
ATOM   12589 C CG1 . VAL E 1 243 ? 100.166 147.260 121.811 1.00 68.52  ? 189 VAL E CG1 1 
ATOM   12590 C CG2 . VAL E 1 243 ? 101.661 145.682 123.044 1.00 69.72  ? 189 VAL E CG2 1 
ATOM   12591 N N   . GLU E 1 244 ? 101.277 146.398 118.588 1.00 73.73  ? 190 GLU E N   1 
ATOM   12592 C CA  . GLU E 1 244 ? 100.817 147.079 117.391 1.00 72.67  ? 190 GLU E CA  1 
ATOM   12593 C C   . GLU E 1 244 ? 101.912 147.024 116.338 1.00 72.87  ? 190 GLU E C   1 
ATOM   12594 O O   . GLU E 1 244 ? 103.098 146.923 116.662 1.00 74.39  ? 190 GLU E O   1 
ATOM   12595 C CB  . GLU E 1 244 ? 100.440 148.533 117.703 1.00 72.28  ? 190 GLU E CB  1 
ATOM   12596 C CG  . GLU E 1 244 ? 99.825  149.299 116.550 1.00 82.29  ? 190 GLU E CG  1 
ATOM   12597 C CD  . GLU E 1 244 ? 99.777  150.788 116.814 1.00 94.09  ? 190 GLU E CD  1 
ATOM   12598 O OE1 . GLU E 1 244 ? 100.420 151.240 117.785 1.00 93.11  ? 190 GLU E OE1 1 
ATOM   12599 O OE2 . GLU E 1 244 ? 99.097  151.507 116.052 1.00 101.42 ? 190 GLU E OE2 1 
ATOM   12600 N N   . HIS E 1 245 ? 101.504 147.082 115.072 1.00 63.09  ? 191 HIS E N   1 
ATOM   12601 C CA  . HIS E 1 245 ? 102.446 147.198 113.972 1.00 57.08  ? 191 HIS E CA  1 
ATOM   12602 C C   . HIS E 1 245 ? 101.939 148.244 112.992 1.00 57.41  ? 191 HIS E C   1 
ATOM   12603 O O   . HIS E 1 245 ? 100.736 148.340 112.733 1.00 63.15  ? 191 HIS E O   1 
ATOM   12604 C CB  . HIS E 1 245 ? 102.674 145.851 113.268 1.00 54.38  ? 191 HIS E CB  1 
ATOM   12605 C CG  . HIS E 1 245 ? 101.580 145.459 112.326 1.00 57.99  ? 191 HIS E CG  1 
ATOM   12606 N ND1 . HIS E 1 245 ? 100.480 144.731 112.722 1.00 61.72  ? 191 HIS E ND1 1 
ATOM   12607 C CD2 . HIS E 1 245 ? 101.428 145.678 110.998 1.00 56.19  ? 191 HIS E CD2 1 
ATOM   12608 C CE1 . HIS E 1 245 ? 99.693  144.525 111.681 1.00 63.87  ? 191 HIS E CE1 1 
ATOM   12609 N NE2 . HIS E 1 245 ? 100.245 145.090 110.623 1.00 61.28  ? 191 HIS E NE2 1 
ATOM   12610 N N   . ARG E 1 246 ? 102.868 149.031 112.463 1.00 57.15  ? 192 ARG E N   1 
ATOM   12611 C CA  . ARG E 1 246 ? 102.571 150.134 111.562 1.00 54.85  ? 192 ARG E CA  1 
ATOM   12612 C C   . ARG E 1 246 ? 103.353 149.979 110.268 1.00 53.20  ? 192 ARG E C   1 
ATOM   12613 O O   . ARG E 1 246 ? 104.512 149.547 110.275 1.00 55.29  ? 192 ARG E O   1 
ATOM   12614 C CB  . ARG E 1 246 ? 102.914 151.486 112.196 1.00 57.46  ? 192 ARG E CB  1 
ATOM   12615 C CG  . ARG E 1 246 ? 102.077 151.862 113.401 1.00 66.48  ? 192 ARG E CG  1 
ATOM   12616 C CD  . ARG E 1 246 ? 102.453 153.250 113.892 1.00 73.58  ? 192 ARG E CD  1 
ATOM   12617 N NE  . ARG E 1 246 ? 101.747 153.618 115.113 1.00 84.85  ? 192 ARG E NE  1 
ATOM   12618 C CZ  . ARG E 1 246 ? 101.948 154.746 115.780 1.00 90.05  ? 192 ARG E CZ  1 
ATOM   12619 N NH1 . ARG E 1 246 ? 102.829 155.644 115.369 1.00 90.68  ? 192 ARG E NH1 1 
ATOM   12620 N NH2 . ARG E 1 246 ? 101.251 154.977 116.888 1.00 87.24  ? 192 ARG E NH2 1 
ATOM   12621 N N   . LEU E 1 247 ? 102.710 150.334 109.159 1.00 48.20  ? 193 LEU E N   1 
ATOM   12622 C CA  . LEU E 1 247 ? 103.343 150.382 107.849 1.00 47.96  ? 193 LEU E CA  1 
ATOM   12623 C C   . LEU E 1 247 ? 103.464 151.835 107.416 1.00 50.68  ? 193 LEU E C   1 
ATOM   12624 O O   . LEU E 1 247 ? 102.462 152.556 107.372 1.00 57.58  ? 193 LEU E O   1 
ATOM   12625 C CB  . LEU E 1 247 ? 102.535 149.593 106.819 1.00 42.40  ? 193 LEU E CB  1 
ATOM   12626 C CG  . LEU E 1 247 ? 102.010 148.230 107.264 1.00 44.04  ? 193 LEU E CG  1 
ATOM   12627 C CD1 . LEU E 1 247 ? 101.286 147.546 106.122 1.00 48.36  ? 193 LEU E CD1 1 
ATOM   12628 C CD2 . LEU E 1 247 ? 103.148 147.369 107.766 1.00 45.16  ? 193 LEU E CD2 1 
ATOM   12629 N N   . VAL E 1 248 ? 104.681 152.259 107.092 1.00 46.85  ? 194 VAL E N   1 
ATOM   12630 C CA  . VAL E 1 248 ? 104.954 153.642 106.719 1.00 44.43  ? 194 VAL E CA  1 
ATOM   12631 C C   . VAL E 1 248 ? 105.626 153.656 105.355 1.00 50.04  ? 194 VAL E C   1 
ATOM   12632 O O   . VAL E 1 248 ? 106.650 152.995 105.158 1.00 57.27  ? 194 VAL E O   1 
ATOM   12633 C CB  . VAL E 1 248 ? 105.838 154.347 107.766 1.00 48.77  ? 194 VAL E CB  1 
ATOM   12634 C CG1 . VAL E 1 248 ? 106.238 155.728 107.279 1.00 61.55  ? 194 VAL E CG1 1 
ATOM   12635 C CG2 . VAL E 1 248 ? 105.110 154.437 109.095 1.00 56.85  ? 194 VAL E CG2 1 
ATOM   12636 N N   . SER E 1 249 ? 105.056 154.407 104.419 1.00 51.57  ? 195 SER E N   1 
ATOM   12637 C CA  . SER E 1 249 ? 105.630 154.594 103.093 1.00 50.42  ? 195 SER E CA  1 
ATOM   12638 C C   . SER E 1 249 ? 106.029 156.053 102.945 1.00 56.93  ? 195 SER E C   1 
ATOM   12639 O O   . SER E 1 249 ? 105.192 156.945 103.120 1.00 75.49  ? 195 SER E O   1 
ATOM   12640 C CB  . SER E 1 249 ? 104.639 154.196 102.000 1.00 50.13  ? 195 SER E CB  1 
ATOM   12641 O OG  . SER E 1 249 ? 105.162 154.481 100.715 1.00 50.89  ? 195 SER E OG  1 
ATOM   12642 N N   . ARG E 1 250 ? 107.294 156.300 102.621 1.00 55.86  ? 196 ARG E N   1 
ATOM   12643 C CA  . ARG E 1 250 ? 107.779 157.672 102.536 1.00 62.49  ? 196 ARG E CA  1 
ATOM   12644 C C   . ARG E 1 250 ? 108.982 157.719 101.601 1.00 60.56  ? 196 ARG E C   1 
ATOM   12645 O O   . ARG E 1 250 ? 109.302 156.742 100.915 1.00 64.68  ? 196 ARG E O   1 
ATOM   12646 C CB  . ARG E 1 250 ? 108.119 158.214 103.928 1.00 65.18  ? 196 ARG E CB  1 
ATOM   12647 C CG  . ARG E 1 250 ? 109.253 157.480 104.620 1.00 64.02  ? 196 ARG E CG  1 
ATOM   12648 C CD  . ARG E 1 250 ? 109.382 157.913 106.068 1.00 71.93  ? 196 ARG E CD  1 
ATOM   12649 N NE  . ARG E 1 250 ? 110.584 157.377 106.694 1.00 73.47  ? 196 ARG E NE  1 
ATOM   12650 C CZ  . ARG E 1 250 ? 111.721 158.046 106.824 1.00 74.51  ? 196 ARG E CZ  1 
ATOM   12651 N NH1 . ARG E 1 250 ? 111.845 159.290 106.392 1.00 70.35  ? 196 ARG E NH1 1 
ATOM   12652 N NH2 . ARG E 1 250 ? 112.759 157.453 107.407 1.00 74.54  ? 196 ARG E NH2 1 
ATOM   12653 N N   . ASN E 1 251 ? 109.641 158.874 101.564 1.00 61.61  ? 197 ASN E N   1 
ATOM   12654 C CA  . ASN E 1 251 ? 110.844 159.089 100.777 1.00 66.11  ? 197 ASN E CA  1 
ATOM   12655 C C   . ASN E 1 251 ? 111.938 159.627 101.686 1.00 69.19  ? 197 ASN E C   1 
ATOM   12656 O O   . ASN E 1 251 ? 111.661 160.284 102.692 1.00 77.64  ? 197 ASN E O   1 
ATOM   12657 C CB  . ASN E 1 251 ? 110.608 160.077 99.623  1.00 65.65  ? 197 ASN E CB  1 
ATOM   12658 C CG  . ASN E 1 251 ? 109.634 159.552 98.586  1.00 67.62  ? 197 ASN E CG  1 
ATOM   12659 O OD1 . ASN E 1 251 ? 108.861 158.635 98.846  1.00 68.98  ? 197 ASN E OD1 1 
ATOM   12660 N ND2 . ASN E 1 251 ? 109.667 160.143 97.398  1.00 66.82  ? 197 ASN E ND2 1 
ATOM   12661 N N   . VAL E 1 252 ? 113.188 159.344 101.322 1.00 66.02  ? 198 VAL E N   1 
ATOM   12662 C CA  . VAL E 1 252 ? 114.343 159.827 102.063 1.00 66.48  ? 198 VAL E CA  1 
ATOM   12663 C C   . VAL E 1 252 ? 115.288 160.498 101.080 1.00 70.93  ? 198 VAL E C   1 
ATOM   12664 O O   . VAL E 1 252 ? 115.252 160.241 99.876  1.00 73.74  ? 198 VAL E O   1 
ATOM   12665 C CB  . VAL E 1 252 ? 115.066 158.700 102.829 1.00 67.05  ? 198 VAL E CB  1 
ATOM   12666 C CG1 . VAL E 1 252 ? 114.162 158.129 103.908 1.00 63.58  ? 198 VAL E CG1 1 
ATOM   12667 C CG2 . VAL E 1 252 ? 115.506 157.611 101.868 1.00 68.41  ? 198 VAL E CG2 1 
ATOM   12668 N N   . VAL E 1 253 ? 116.140 161.373 101.605 1.00 74.56  ? 199 VAL E N   1 
ATOM   12669 C CA  . VAL E 1 253 ? 117.044 162.174 100.790 1.00 76.33  ? 199 VAL E CA  1 
ATOM   12670 C C   . VAL E 1 253 ? 118.474 161.915 101.239 1.00 84.49  ? 199 VAL E C   1 
ATOM   12671 O O   . VAL E 1 253 ? 118.797 162.068 102.422 1.00 85.51  ? 199 VAL E O   1 
ATOM   12672 C CB  . VAL E 1 253 ? 116.708 163.673 100.877 1.00 66.90  ? 199 VAL E CB  1 
ATOM   12673 C CG1 . VAL E 1 253 ? 117.754 164.494 100.143 1.00 66.78  ? 199 VAL E CG1 1 
ATOM   12674 C CG2 . VAL E 1 253 ? 115.324 163.937 100.309 1.00 62.90  ? 199 VAL E CG2 1 
ATOM   12675 N N   . PHE E 1 254 ? 119.323 161.522 100.295 1.00 86.83  ? 200 PHE E N   1 
ATOM   12676 C CA  . PHE E 1 254 ? 120.757 161.403 100.489 1.00 89.06  ? 200 PHE E CA  1 
ATOM   12677 C C   . PHE E 1 254 ? 121.460 162.254 99.441  1.00 93.13  ? 200 PHE E C   1 
ATOM   12678 O O   . PHE E 1 254 ? 120.832 162.812 98.537  1.00 92.74  ? 200 PHE E O   1 
ATOM   12679 C CB  . PHE E 1 254 ? 121.217 159.943 100.392 1.00 84.34  ? 200 PHE E CB  1 
ATOM   12680 C CG  . PHE E 1 254 ? 120.756 159.082 101.532 1.00 89.05  ? 200 PHE E CG  1 
ATOM   12681 C CD1 . PHE E 1 254 ? 119.466 158.579 101.562 1.00 84.62  ? 200 PHE E CD1 1 
ATOM   12682 C CD2 . PHE E 1 254 ? 121.617 158.768 102.570 1.00 94.96  ? 200 PHE E CD2 1 
ATOM   12683 C CE1 . PHE E 1 254 ? 119.042 157.784 102.610 1.00 83.36  ? 200 PHE E CE1 1 
ATOM   12684 C CE2 . PHE E 1 254 ? 121.198 157.973 103.619 1.00 96.10  ? 200 PHE E CE2 1 
ATOM   12685 C CZ  . PHE E 1 254 ? 119.909 157.481 103.639 1.00 88.11  ? 200 PHE E CZ  1 
ATOM   12686 N N   . ALA E 1 255 ? 122.787 162.334 99.558  1.00 95.53  ? 201 ALA E N   1 
ATOM   12687 C CA  . ALA E 1 255 ? 123.561 163.151 98.630  1.00 95.99  ? 201 ALA E CA  1 
ATOM   12688 C C   . ALA E 1 255 ? 123.432 162.672 97.190  1.00 100.75 ? 201 ALA E C   1 
ATOM   12689 O O   . ALA E 1 255 ? 123.711 163.444 96.266  1.00 102.49 ? 201 ALA E O   1 
ATOM   12690 C CB  . ALA E 1 255 ? 125.033 163.167 99.043  1.00 89.83  ? 201 ALA E CB  1 
ATOM   12691 N N   . THR E 1 256 ? 123.013 161.426 96.977  1.00 99.81  ? 202 THR E N   1 
ATOM   12692 C CA  . THR E 1 256 ? 122.832 160.883 95.639  1.00 96.20  ? 202 THR E CA  1 
ATOM   12693 C C   . THR E 1 256 ? 121.399 160.996 95.131  1.00 94.35  ? 202 THR E C   1 
ATOM   12694 O O   . THR E 1 256 ? 121.128 160.575 94.003  1.00 92.81  ? 202 THR E O   1 
ATOM   12695 C CB  . THR E 1 256 ? 123.277 159.417 95.596  1.00 90.67  ? 202 THR E CB  1 
ATOM   12696 O OG1 . THR E 1 256 ? 122.676 158.698 96.679  1.00 91.28  ? 202 THR E OG1 1 
ATOM   12697 C CG2 . THR E 1 256 ? 124.791 159.315 95.698  1.00 86.91  ? 202 THR E CG2 1 
ATOM   12698 N N   . GLY E 1 257 ? 120.477 161.544 95.924  1.00 90.50  ? 203 GLY E N   1 
ATOM   12699 C CA  . GLY E 1 257 ? 119.128 161.772 95.453  1.00 87.74  ? 203 GLY E CA  1 
ATOM   12700 C C   . GLY E 1 257 ? 118.096 161.287 96.444  1.00 79.75  ? 203 GLY E C   1 
ATOM   12701 O O   . GLY E 1 257 ? 118.391 161.011 97.611  1.00 82.98  ? 203 GLY E O   1 
ATOM   12702 N N   . ALA E 1 258 ? 116.856 161.183 95.975  1.00 71.66  ? 204 ALA E N   1 
ATOM   12703 C CA  . ALA E 1 258 ? 115.733 160.772 96.807  1.00 68.99  ? 204 ALA E CA  1 
ATOM   12704 C C   . ALA E 1 258 ? 115.383 159.317 96.527  1.00 69.97  ? 204 ALA E C   1 
ATOM   12705 O O   . ALA E 1 258 ? 115.147 158.941 95.374  1.00 72.33  ? 204 ALA E O   1 
ATOM   12706 C CB  . ALA E 1 258 ? 114.516 161.665 96.561  1.00 66.15  ? 204 ALA E CB  1 
ATOM   12707 N N   . TYR E 1 259 ? 115.338 158.509 97.585  1.00 65.11  ? 205 TYR E N   1 
ATOM   12708 C CA  . TYR E 1 259 ? 115.063 157.084 97.516  1.00 57.44  ? 205 TYR E CA  1 
ATOM   12709 C C   . TYR E 1 259 ? 113.737 156.748 98.189  1.00 55.75  ? 205 TYR E C   1 
ATOM   12710 O O   . TYR E 1 259 ? 113.386 157.355 99.207  1.00 59.02  ? 205 TYR E O   1 
ATOM   12711 C CB  . TYR E 1 259 ? 116.183 156.277 98.185  1.00 59.49  ? 205 TYR E CB  1 
ATOM   12712 C CG  . TYR E 1 259 ? 117.540 156.433 97.537  1.00 64.24  ? 205 TYR E CG  1 
ATOM   12713 C CD1 . TYR E 1 259 ? 118.406 157.447 97.927  1.00 69.37  ? 205 TYR E CD1 1 
ATOM   12714 C CD2 . TYR E 1 259 ? 117.959 155.563 96.543  1.00 62.98  ? 205 TYR E CD2 1 
ATOM   12715 C CE1 . TYR E 1 259 ? 119.648 157.590 97.338  1.00 75.46  ? 205 TYR E CE1 1 
ATOM   12716 C CE2 . TYR E 1 259 ? 119.198 155.699 95.949  1.00 64.72  ? 205 TYR E CE2 1 
ATOM   12717 C CZ  . TYR E 1 259 ? 120.038 156.713 96.350  1.00 76.80  ? 205 TYR E CZ  1 
ATOM   12718 O OH  . TYR E 1 259 ? 121.273 156.849 95.760  1.00 85.23  ? 205 TYR E OH  1 
ATOM   12719 N N   . PRO E 1 260 ? 112.983 155.791 97.652  1.00 50.05  ? 206 PRO E N   1 
ATOM   12720 C CA  . PRO E 1 260 ? 111.756 155.353 98.324  1.00 49.37  ? 206 PRO E CA  1 
ATOM   12721 C C   . PRO E 1 260 ? 112.076 154.565 99.583  1.00 49.83  ? 206 PRO E C   1 
ATOM   12722 O O   . PRO E 1 260 ? 113.163 154.006 99.740  1.00 57.21  ? 206 PRO E O   1 
ATOM   12723 C CB  . PRO E 1 260 ? 111.075 154.471 97.273  1.00 46.62  ? 206 PRO E CB  1 
ATOM   12724 C CG  . PRO E 1 260 ? 112.202 153.950 96.455  1.00 48.49  ? 206 PRO E CG  1 
ATOM   12725 C CD  . PRO E 1 260 ? 113.217 155.058 96.397  1.00 50.66  ? 206 PRO E CD  1 
ATOM   12726 N N   . ARG E 1 261 ? 111.106 154.518 100.494 1.00 49.29  ? 207 ARG E N   1 
ATOM   12727 C CA  . ARG E 1 261 ? 111.325 153.872 101.777 1.00 45.06  ? 207 ARG E CA  1 
ATOM   12728 C C   . ARG E 1 261 ? 110.025 153.270 102.288 1.00 45.99  ? 207 ARG E C   1 
ATOM   12729 O O   . ARG E 1 261 ? 108.976 153.922 102.263 1.00 55.09  ? 207 ARG E O   1 
ATOM   12730 C CB  . ARG E 1 261 ? 111.874 154.868 102.804 1.00 48.98  ? 207 ARG E CB  1 
ATOM   12731 C CG  . ARG E 1 261 ? 111.949 154.326 104.217 1.00 52.55  ? 207 ARG E CG  1 
ATOM   12732 C CD  . ARG E 1 261 ? 113.154 153.429 104.398 1.00 52.55  ? 207 ARG E CD  1 
ATOM   12733 N NE  . ARG E 1 261 ? 114.397 154.187 104.354 1.00 57.08  ? 207 ARG E NE  1 
ATOM   12734 C CZ  . ARG E 1 261 ? 114.925 154.814 105.395 1.00 57.74  ? 207 ARG E CZ  1 
ATOM   12735 N NH1 . ARG E 1 261 ? 114.340 154.795 106.581 1.00 55.36  ? 207 ARG E NH1 1 
ATOM   12736 N NH2 . ARG E 1 261 ? 116.069 155.476 105.243 1.00 55.24  ? 207 ARG E NH2 1 
ATOM   12737 N N   . LEU E 1 262 ? 110.111 152.030 102.759 1.00 41.69  ? 208 LEU E N   1 
ATOM   12738 C CA  . LEU E 1 262 ? 109.036 151.379 103.488 1.00 41.39  ? 208 LEU E CA  1 
ATOM   12739 C C   . LEU E 1 262 ? 109.533 151.031 104.882 1.00 49.12  ? 208 LEU E C   1 
ATOM   12740 O O   . LEU E 1 262 ? 110.720 150.777 105.087 1.00 54.94  ? 208 LEU E O   1 
ATOM   12741 C CB  . LEU E 1 262 ? 108.553 150.112 102.778 1.00 39.97  ? 208 LEU E CB  1 
ATOM   12742 C CG  . LEU E 1 262 ? 107.943 150.280 101.388 1.00 43.34  ? 208 LEU E CG  1 
ATOM   12743 C CD1 . LEU E 1 262 ? 107.503 148.935 100.846 1.00 45.40  ? 208 LEU E CD1 1 
ATOM   12744 C CD2 . LEU E 1 262 ? 106.774 151.244 101.431 1.00 43.14  ? 208 LEU E CD2 1 
ATOM   12745 N N   . SER E 1 263 ? 108.619 151.024 105.846 1.00 44.68  ? 209 SER E N   1 
ATOM   12746 C CA  . SER E 1 263 ? 108.979 150.754 107.230 1.00 41.71  ? 209 SER E CA  1 
ATOM   12747 C C   . SER E 1 263 ? 107.883 149.925 107.871 1.00 42.95  ? 209 SER E C   1 
ATOM   12748 O O   . SER E 1 263 ? 106.725 150.350 107.912 1.00 51.68  ? 209 SER E O   1 
ATOM   12749 C CB  . SER E 1 263 ? 109.195 152.055 108.005 1.00 51.41  ? 209 SER E CB  1 
ATOM   12750 O OG  . SER E 1 263 ? 110.219 152.832 107.411 1.00 59.36  ? 209 SER E OG  1 
ATOM   12751 N N   . LEU E 1 264 ? 108.250 148.743 108.356 1.00 44.01  ? 210 LEU E N   1 
ATOM   12752 C CA  . LEU E 1 264 ? 107.355 147.880 109.120 1.00 45.13  ? 210 LEU E CA  1 
ATOM   12753 C C   . LEU E 1 264 ? 107.812 147.929 110.571 1.00 44.67  ? 210 LEU E C   1 
ATOM   12754 O O   . LEU E 1 264 ? 108.892 147.433 110.899 1.00 48.77  ? 210 LEU E O   1 
ATOM   12755 C CB  . LEU E 1 264 ? 107.378 146.456 108.571 1.00 43.77  ? 210 LEU E CB  1 
ATOM   12756 C CG  . LEU E 1 264 ? 106.896 145.320 109.474 1.00 43.45  ? 210 LEU E CG  1 
ATOM   12757 C CD1 . LEU E 1 264 ? 105.436 145.495 109.843 1.00 43.56  ? 210 LEU E CD1 1 
ATOM   12758 C CD2 . LEU E 1 264 ? 107.121 143.979 108.796 1.00 44.01  ? 210 LEU E CD2 1 
ATOM   12759 N N   . SER E 1 265 ? 107.007 148.534 111.437 1.00 42.41  ? 211 SER E N   1 
ATOM   12760 C CA  . SER E 1 265 ? 107.394 148.748 112.823 1.00 46.17  ? 211 SER E CA  1 
ATOM   12761 C C   . SER E 1 265 ? 106.493 147.955 113.756 1.00 52.59  ? 211 SER E C   1 
ATOM   12762 O O   . SER E 1 265 ? 105.274 147.926 113.574 1.00 61.85  ? 211 SER E O   1 
ATOM   12763 C CB  . SER E 1 265 ? 107.330 150.232 113.185 1.00 50.64  ? 211 SER E CB  1 
ATOM   12764 O OG  . SER E 1 265 ? 108.138 151.003 112.314 1.00 59.19  ? 211 SER E OG  1 
ATOM   12765 N N   . PHE E 1 266 ? 107.095 147.316 114.755 1.00 49.26  ? 212 PHE E N   1 
ATOM   12766 C CA  . PHE E 1 266 ? 106.366 146.654 115.824 1.00 48.53  ? 212 PHE E CA  1 
ATOM   12767 C C   . PHE E 1 266 ? 106.654 147.362 117.137 1.00 56.77  ? 212 PHE E C   1 
ATOM   12768 O O   . PHE E 1 266 ? 107.786 147.792 117.385 1.00 64.05  ? 212 PHE E O   1 
ATOM   12769 C CB  . PHE E 1 266 ? 106.761 145.182 115.961 1.00 49.21  ? 212 PHE E CB  1 
ATOM   12770 C CG  . PHE E 1 266 ? 106.957 144.477 114.657 1.00 49.91  ? 212 PHE E CG  1 
ATOM   12771 C CD1 . PHE E 1 266 ? 105.881 143.941 113.976 1.00 50.25  ? 212 PHE E CD1 1 
ATOM   12772 C CD2 . PHE E 1 266 ? 108.225 144.330 114.122 1.00 51.20  ? 212 PHE E CD2 1 
ATOM   12773 C CE1 . PHE E 1 266 ? 106.063 143.286 112.780 1.00 53.16  ? 212 PHE E CE1 1 
ATOM   12774 C CE2 . PHE E 1 266 ? 108.413 143.676 112.928 1.00 51.59  ? 212 PHE E CE2 1 
ATOM   12775 C CZ  . PHE E 1 266 ? 107.332 143.153 112.257 1.00 56.24  ? 212 PHE E CZ  1 
ATOM   12776 N N   . ARG E 1 267 ? 105.633 147.474 117.979 1.00 60.19  ? 213 ARG E N   1 
ATOM   12777 C CA  . ARG E 1 267 ? 105.800 147.945 119.347 1.00 63.06  ? 213 ARG E CA  1 
ATOM   12778 C C   . ARG E 1 267 ? 105.610 146.758 120.280 1.00 63.60  ? 213 ARG E C   1 
ATOM   12779 O O   . ARG E 1 267 ? 104.530 146.159 120.319 1.00 65.69  ? 213 ARG E O   1 
ATOM   12780 C CB  . ARG E 1 267 ? 104.820 149.071 119.677 1.00 63.45  ? 213 ARG E CB  1 
ATOM   12781 C CG  . ARG E 1 267 ? 105.298 149.959 120.814 1.00 67.86  ? 213 ARG E CG  1 
ATOM   12782 C CD  . ARG E 1 267 ? 104.512 151.256 120.900 1.00 77.13  ? 213 ARG E CD  1 
ATOM   12783 N NE  . ARG E 1 267 ? 103.198 151.074 121.505 1.00 89.01  ? 213 ARG E NE  1 
ATOM   12784 C CZ  . ARG E 1 267 ? 102.064 150.988 120.824 1.00 89.24  ? 213 ARG E CZ  1 
ATOM   12785 N NH1 . ARG E 1 267 ? 102.043 151.058 119.504 1.00 85.38  ? 213 ARG E NH1 1 
ATOM   12786 N NH2 . ARG E 1 267 ? 100.921 150.832 121.486 1.00 88.70  ? 213 ARG E NH2 1 
ATOM   12787 N N   . LEU E 1 268 ? 106.658 146.425 121.025 1.00 64.89  ? 214 LEU E N   1 
ATOM   12788 C CA  . LEU E 1 268 ? 106.697 145.241 121.871 1.00 67.35  ? 214 LEU E CA  1 
ATOM   12789 C C   . LEU E 1 268 ? 106.605 145.649 123.333 1.00 71.60  ? 214 LEU E C   1 
ATOM   12790 O O   . LEU E 1 268 ? 107.370 146.504 123.792 1.00 70.96  ? 214 LEU E O   1 
ATOM   12791 C CB  . LEU E 1 268 ? 107.984 144.448 121.640 1.00 68.57  ? 214 LEU E CB  1 
ATOM   12792 C CG  . LEU E 1 268 ? 108.454 144.226 120.202 1.00 59.81  ? 214 LEU E CG  1 
ATOM   12793 C CD1 . LEU E 1 268 ? 109.823 143.574 120.199 1.00 60.22  ? 214 LEU E CD1 1 
ATOM   12794 C CD2 . LEU E 1 268 ? 107.461 143.376 119.438 1.00 59.41  ? 214 LEU E CD2 1 
ATOM   12795 N N   . LYS E 1 269 ? 105.678 145.032 124.060 1.00 76.23  ? 215 LYS E N   1 
ATOM   12796 C CA  . LYS E 1 269 ? 105.559 145.212 125.500 1.00 73.37  ? 215 LYS E CA  1 
ATOM   12797 C C   . LYS E 1 269 ? 106.142 143.986 126.189 1.00 69.63  ? 215 LYS E C   1 
ATOM   12798 O O   . LYS E 1 269 ? 105.662 142.867 125.984 1.00 75.59  ? 215 LYS E O   1 
ATOM   12799 C CB  . LYS E 1 269 ? 104.102 145.423 125.910 1.00 80.65  ? 215 LYS E CB  1 
ATOM   12800 C CG  . LYS E 1 269 ? 103.914 145.656 127.399 1.00 85.04  ? 215 LYS E CG  1 
ATOM   12801 C CD  . LYS E 1 269 ? 102.453 145.867 127.757 1.00 95.31  ? 215 LYS E CD  1 
ATOM   12802 C CE  . LYS E 1 269 ? 102.292 146.110 129.249 1.00 98.68  ? 215 LYS E CE  1 
ATOM   12803 N NZ  . LYS E 1 269 ? 100.870 146.304 129.643 1.00 93.67  ? 215 LYS E NZ  1 
ATOM   12804 N N   . ARG E 1 270 ? 107.170 144.200 127.004 1.00 70.37  ? 216 ARG E N   1 
ATOM   12805 C CA  . ARG E 1 270 ? 107.854 143.094 127.658 1.00 72.96  ? 216 ARG E CA  1 
ATOM   12806 C C   . ARG E 1 270 ? 106.989 142.511 128.768 1.00 72.11  ? 216 ARG E C   1 
ATOM   12807 O O   . ARG E 1 270 ? 106.424 143.250 129.580 1.00 77.15  ? 216 ARG E O   1 
ATOM   12808 C CB  . ARG E 1 270 ? 109.192 143.568 128.220 1.00 71.25  ? 216 ARG E CB  1 
ATOM   12809 C CG  . ARG E 1 270 ? 110.084 142.456 128.735 1.00 72.60  ? 216 ARG E CG  1 
ATOM   12810 C CD  . ARG E 1 270 ? 111.353 143.022 129.343 1.00 74.56  ? 216 ARG E CD  1 
ATOM   12811 N NE  . ARG E 1 270 ? 112.076 143.878 128.410 1.00 75.77  ? 216 ARG E NE  1 
ATOM   12812 C CZ  . ARG E 1 270 ? 113.097 143.479 127.666 1.00 79.37  ? 216 ARG E CZ  1 
ATOM   12813 N NH1 . ARG E 1 270 ? 113.544 142.235 127.717 1.00 81.24  ? 216 ARG E NH1 1 
ATOM   12814 N NH2 . ARG E 1 270 ? 113.689 144.350 126.854 1.00 80.08  ? 216 ARG E NH2 1 
ATOM   12815 N N   . ASN E 1 271 ? 106.883 141.185 128.800 1.00 71.07  ? 217 ASN E N   1 
ATOM   12816 C CA  . ASN E 1 271 ? 106.157 140.523 129.874 1.00 76.27  ? 217 ASN E CA  1 
ATOM   12817 C C   . ASN E 1 271 ? 106.895 140.699 131.196 1.00 85.48  ? 217 ASN E C   1 
ATOM   12818 O O   . ASN E 1 271 ? 108.119 140.564 131.267 1.00 88.64  ? 217 ASN E O   1 
ATOM   12819 C CB  . ASN E 1 271 ? 105.970 139.039 129.562 1.00 74.65  ? 217 ASN E CB  1 
ATOM   12820 C CG  . ASN E 1 271 ? 105.035 138.805 128.393 1.00 72.82  ? 217 ASN E CG  1 
ATOM   12821 O OD1 . ASN E 1 271 ? 104.176 139.635 128.094 1.00 74.18  ? 217 ASN E OD1 1 
ATOM   12822 N ND2 . ASN E 1 271 ? 105.196 137.668 127.726 1.00 72.89  ? 217 ASN E ND2 1 
ATOM   12823 N N   . ILE E 1 272 ? 106.136 140.998 132.248 1.00 84.52  ? 218 ILE E N   1 
ATOM   12824 C CA  . ILE E 1 272 ? 106.715 141.402 133.524 1.00 82.99  ? 218 ILE E CA  1 
ATOM   12825 C C   . ILE E 1 272 ? 106.765 140.269 134.549 1.00 82.68  ? 218 ILE E C   1 
ATOM   12826 O O   . ILE E 1 272 ? 107.550 140.354 135.507 1.00 85.52  ? 218 ILE E O   1 
ATOM   12827 C CB  . ILE E 1 272 ? 105.938 142.613 134.085 1.00 80.48  ? 218 ILE E CB  1 
ATOM   12828 C CG1 . ILE E 1 272 ? 106.644 143.216 135.302 1.00 82.21  ? 218 ILE E CG1 1 
ATOM   12829 C CG2 . ILE E 1 272 ? 104.502 142.224 134.410 1.00 78.70  ? 218 ILE E CG2 1 
ATOM   12830 C CD1 . ILE E 1 272 ? 108.069 143.634 135.029 1.00 81.70  ? 218 ILE E CD1 1 
ATOM   12831 N N   . GLY E 1 273 ? 105.983 139.203 134.362 1.00 74.17  ? 219 GLY E N   1 
ATOM   12832 C CA  . GLY E 1 273 ? 105.891 138.168 135.382 1.00 76.41  ? 219 GLY E CA  1 
ATOM   12833 C C   . GLY E 1 273 ? 107.218 137.497 135.689 1.00 81.53  ? 219 GLY E C   1 
ATOM   12834 O O   . GLY E 1 273 ? 107.519 137.199 136.849 1.00 88.58  ? 219 GLY E O   1 
ATOM   12835 N N   . TYR E 1 274 ? 108.024 137.241 134.657 1.00 78.61  ? 220 TYR E N   1 
ATOM   12836 C CA  . TYR E 1 274 ? 109.298 136.558 134.862 1.00 82.18  ? 220 TYR E CA  1 
ATOM   12837 C C   . TYR E 1 274 ? 110.219 137.365 135.768 1.00 84.40  ? 220 TYR E C   1 
ATOM   12838 O O   . TYR E 1 274 ? 110.782 136.837 136.735 1.00 86.11  ? 220 TYR E O   1 
ATOM   12839 C CB  . TYR E 1 274 ? 109.967 136.290 133.514 1.00 91.94  ? 220 TYR E CB  1 
ATOM   12840 C CG  . TYR E 1 274 ? 111.424 135.905 133.621 1.00 93.67  ? 220 TYR E CG  1 
ATOM   12841 C CD1 . TYR E 1 274 ? 111.799 134.610 133.950 1.00 95.82  ? 220 TYR E CD1 1 
ATOM   12842 C CD2 . TYR E 1 274 ? 112.426 136.837 133.386 1.00 93.89  ? 220 TYR E CD2 1 
ATOM   12843 C CE1 . TYR E 1 274 ? 113.129 134.255 134.048 1.00 99.01  ? 220 TYR E CE1 1 
ATOM   12844 C CE2 . TYR E 1 274 ? 113.758 136.491 133.482 1.00 98.60  ? 220 TYR E CE2 1 
ATOM   12845 C CZ  . TYR E 1 274 ? 114.104 135.200 133.812 1.00 101.52 ? 220 TYR E CZ  1 
ATOM   12846 O OH  . TYR E 1 274 ? 115.431 134.854 133.907 1.00 105.60 ? 220 TYR E OH  1 
ATOM   12847 N N   . PHE E 1 275 ? 110.384 138.655 135.472 1.00 87.83  ? 221 PHE E N   1 
ATOM   12848 C CA  . PHE E 1 275 ? 111.251 139.489 136.295 1.00 87.00  ? 221 PHE E CA  1 
ATOM   12849 C C   . PHE E 1 275 ? 110.613 139.804 137.638 1.00 81.79  ? 221 PHE E C   1 
ATOM   12850 O O   . PHE E 1 275 ? 111.323 140.094 138.607 1.00 81.31  ? 221 PHE E O   1 
ATOM   12851 C CB  . PHE E 1 275 ? 111.603 140.770 135.546 1.00 91.53  ? 221 PHE E CB  1 
ATOM   12852 C CG  . PHE E 1 275 ? 112.343 140.529 134.268 1.00 96.30  ? 221 PHE E CG  1 
ATOM   12853 C CD1 . PHE E 1 275 ? 113.713 140.338 134.276 1.00 97.08  ? 221 PHE E CD1 1 
ATOM   12854 C CD2 . PHE E 1 275 ? 111.669 140.475 133.060 1.00 92.00  ? 221 PHE E CD2 1 
ATOM   12855 C CE1 . PHE E 1 275 ? 114.398 140.107 133.105 1.00 98.81  ? 221 PHE E CE1 1 
ATOM   12856 C CE2 . PHE E 1 275 ? 112.350 140.247 131.884 1.00 93.25  ? 221 PHE E CE2 1 
ATOM   12857 C CZ  . PHE E 1 275 ? 113.717 140.063 131.906 1.00 98.63  ? 221 PHE E CZ  1 
ATOM   12858 N N   . ILE E 1 276 ? 109.282 139.763 137.712 1.00 79.10  ? 222 ILE E N   1 
ATOM   12859 C CA  . ILE E 1 276 ? 108.608 139.866 139.003 1.00 78.01  ? 222 ILE E CA  1 
ATOM   12860 C C   . ILE E 1 276 ? 109.015 138.704 139.898 1.00 79.35  ? 222 ILE E C   1 
ATOM   12861 O O   . ILE E 1 276 ? 109.353 138.888 141.073 1.00 81.15  ? 222 ILE E O   1 
ATOM   12862 C CB  . ILE E 1 276 ? 107.083 139.926 138.808 1.00 77.31  ? 222 ILE E CB  1 
ATOM   12863 C CG1 . ILE E 1 276 ? 106.642 141.358 138.508 1.00 74.28  ? 222 ILE E CG1 1 
ATOM   12864 C CG2 . ILE E 1 276 ? 106.358 139.391 140.032 1.00 77.35  ? 222 ILE E CG2 1 
ATOM   12865 C CD1 . ILE E 1 276 ? 106.852 142.305 139.664 1.00 75.04  ? 222 ILE E CD1 1 
ATOM   12866 N N   . LEU E 1 277 ? 109.012 137.491 139.348 1.00 79.96  ? 223 LEU E N   1 
ATOM   12867 C CA  . LEU E 1 277 ? 109.343 136.306 140.129 1.00 78.75  ? 223 LEU E CA  1 
ATOM   12868 C C   . LEU E 1 277 ? 110.840 136.051 140.242 1.00 77.98  ? 223 LEU E C   1 
ATOM   12869 O O   . LEU E 1 277 ? 111.240 135.166 141.005 1.00 80.42  ? 223 LEU E O   1 
ATOM   12870 C CB  . LEU E 1 277 ? 108.667 135.073 139.527 1.00 81.82  ? 223 LEU E CB  1 
ATOM   12871 C CG  . LEU E 1 277 ? 107.144 135.011 139.623 1.00 83.87  ? 223 LEU E CG  1 
ATOM   12872 C CD1 . LEU E 1 277 ? 106.631 133.715 139.018 1.00 86.29  ? 223 LEU E CD1 1 
ATOM   12873 C CD2 . LEU E 1 277 ? 106.699 135.145 141.069 1.00 80.57  ? 223 LEU E CD2 1 
ATOM   12874 N N   . GLN E 1 278 ? 111.673 136.782 139.507 1.00 79.34  ? 224 GLN E N   1 
ATOM   12875 C CA  . GLN E 1 278 ? 113.112 136.541 139.517 1.00 80.76  ? 224 GLN E CA  1 
ATOM   12876 C C   . GLN E 1 278 ? 113.923 137.637 140.189 1.00 79.58  ? 224 GLN E C   1 
ATOM   12877 O O   . GLN E 1 278 ? 114.806 137.334 140.993 1.00 80.19  ? 224 GLN E O   1 
ATOM   12878 C CB  . GLN E 1 278 ? 113.626 136.351 138.086 1.00 86.11  ? 224 GLN E CB  1 
ATOM   12879 C CG  . GLN E 1 278 ? 115.118 136.089 138.007 1.00 84.35  ? 224 GLN E CG  1 
ATOM   12880 C CD  . GLN E 1 278 ? 115.530 134.867 138.802 1.00 89.77  ? 224 GLN E CD  1 
ATOM   12881 O OE1 . GLN E 1 278 ? 114.903 133.813 138.711 1.00 91.58  ? 224 GLN E OE1 1 
ATOM   12882 N NE2 . GLN E 1 278 ? 116.586 135.006 139.595 1.00 88.00  ? 224 GLN E NE2 1 
ATOM   12883 N N   . THR E 1 279 ? 113.661 138.906 139.879 1.00 80.93  ? 225 THR E N   1 
ATOM   12884 C CA  . THR E 1 279 ? 114.508 139.998 140.337 1.00 78.95  ? 225 THR E CA  1 
ATOM   12885 C C   . THR E 1 279 ? 113.854 140.886 141.388 1.00 79.46  ? 225 THR E C   1 
ATOM   12886 O O   . THR E 1 279 ? 114.497 141.830 141.860 1.00 80.56  ? 225 THR E O   1 
ATOM   12887 C CB  . THR E 1 279 ? 114.948 140.858 139.146 1.00 83.80  ? 225 THR E CB  1 
ATOM   12888 O OG1 . THR E 1 279 ? 113.795 141.354 138.456 1.00 82.84  ? 225 THR E OG1 1 
ATOM   12889 C CG2 . THR E 1 279 ? 115.795 140.039 138.183 1.00 85.92  ? 225 THR E CG2 1 
ATOM   12890 N N   . TYR E 1 280 ? 112.609 140.617 141.775 1.00 79.08  ? 226 TYR E N   1 
ATOM   12891 C CA  . TYR E 1 280 ? 111.924 141.434 142.770 1.00 80.51  ? 226 TYR E CA  1 
ATOM   12892 C C   . TYR E 1 280 ? 111.567 140.658 144.027 1.00 82.09  ? 226 TYR E C   1 
ATOM   12893 O O   . TYR E 1 280 ? 111.806 141.147 145.141 1.00 86.31  ? 226 TYR E O   1 
ATOM   12894 C CB  . TYR E 1 280 ? 110.659 142.061 142.161 1.00 75.93  ? 226 TYR E CB  1 
ATOM   12895 C CG  . TYR E 1 280 ? 110.946 143.188 141.195 1.00 74.93  ? 226 TYR E CG  1 
ATOM   12896 C CD1 . TYR E 1 280 ? 111.279 142.927 139.875 1.00 76.74  ? 226 TYR E CD1 1 
ATOM   12897 C CD2 . TYR E 1 280 ? 110.885 144.512 141.604 1.00 74.03  ? 226 TYR E CD2 1 
ATOM   12898 C CE1 . TYR E 1 280 ? 111.543 143.951 138.988 1.00 73.34  ? 226 TYR E CE1 1 
ATOM   12899 C CE2 . TYR E 1 280 ? 111.148 145.544 140.723 1.00 76.57  ? 226 TYR E CE2 1 
ATOM   12900 C CZ  . TYR E 1 280 ? 111.476 145.257 139.418 1.00 72.86  ? 226 TYR E CZ  1 
ATOM   12901 O OH  . TYR E 1 280 ? 111.739 146.279 138.536 1.00 68.74  ? 226 TYR E OH  1 
ATOM   12902 N N   . MET E 1 281 ? 110.989 139.467 143.885 1.00 82.45  ? 227 MET E N   1 
ATOM   12903 C CA  . MET E 1 281 ? 110.650 138.671 145.062 1.00 82.05  ? 227 MET E CA  1 
ATOM   12904 C C   . MET E 1 281 ? 111.858 138.334 145.928 1.00 81.23  ? 227 MET E C   1 
ATOM   12905 O O   . MET E 1 281 ? 111.739 138.442 147.161 1.00 84.47  ? 227 MET E O   1 
ATOM   12906 C CB  . MET E 1 281 ? 109.912 137.394 144.639 1.00 83.46  ? 227 MET E CB  1 
ATOM   12907 C CG  . MET E 1 281 ? 108.624 137.642 143.876 1.00 95.67  ? 227 MET E CG  1 
ATOM   12908 S SD  . MET E 1 281 ? 107.453 138.671 144.781 1.00 117.22 ? 227 MET E SD  1 
ATOM   12909 C CE  . MET E 1 281 ? 107.087 137.621 146.185 1.00 101.52 ? 227 MET E CE  1 
ATOM   12910 N N   . PRO E 1 282 ? 113.007 137.899 145.390 1.00 79.55  ? 228 PRO E N   1 
ATOM   12911 C CA  . PRO E 1 282 ? 114.171 137.697 146.271 1.00 82.23  ? 228 PRO E CA  1 
ATOM   12912 C C   . PRO E 1 282 ? 114.593 138.956 147.006 1.00 84.85  ? 228 PRO E C   1 
ATOM   12913 O O   . PRO E 1 282 ? 114.960 138.884 148.185 1.00 87.41  ? 228 PRO E O   1 
ATOM   12914 C CB  . PRO E 1 282 ? 115.257 137.207 145.304 1.00 76.01  ? 228 PRO E CB  1 
ATOM   12915 C CG  . PRO E 1 282 ? 114.509 136.597 144.184 1.00 81.70  ? 228 PRO E CG  1 
ATOM   12916 C CD  . PRO E 1 282 ? 113.293 137.451 144.014 1.00 80.52  ? 228 PRO E CD  1 
ATOM   12917 N N   . SER E 1 283 ? 114.535 140.116 146.346 1.00 81.43  ? 229 SER E N   1 
ATOM   12918 C CA  . SER E 1 283 ? 114.897 141.362 147.013 1.00 81.26  ? 229 SER E CA  1 
ATOM   12919 C C   . SER E 1 283 ? 113.945 141.668 148.162 1.00 82.37  ? 229 SER E C   1 
ATOM   12920 O O   . SER E 1 283 ? 114.378 142.060 149.254 1.00 85.33  ? 229 SER E O   1 
ATOM   12921 C CB  . SER E 1 283 ? 114.907 142.511 146.007 1.00 80.09  ? 229 SER E CB  1 
ATOM   12922 O OG  . SER E 1 283 ? 115.671 142.177 144.863 1.00 88.06  ? 229 SER E OG  1 
ATOM   12923 N N   . ILE E 1 284 ? 112.643 141.487 147.938 1.00 79.58  ? 230 ILE E N   1 
ATOM   12924 C CA  . ILE E 1 284 ? 111.672 141.761 148.991 1.00 80.38  ? 230 ILE E CA  1 
ATOM   12925 C C   . ILE E 1 284 ? 111.838 140.777 150.144 1.00 82.93  ? 230 ILE E C   1 
ATOM   12926 O O   . ILE E 1 284 ? 111.718 141.148 151.319 1.00 88.85  ? 230 ILE E O   1 
ATOM   12927 C CB  . ILE E 1 284 ? 110.244 141.738 148.421 1.00 84.30  ? 230 ILE E CB  1 
ATOM   12928 C CG1 . ILE E 1 284 ? 110.106 142.764 147.295 1.00 82.64  ? 230 ILE E CG1 1 
ATOM   12929 C CG2 . ILE E 1 284 ? 109.232 142.024 149.513 1.00 88.64  ? 230 ILE E CG2 1 
ATOM   12930 C CD1 . ILE E 1 284 ? 108.758 142.741 146.606 1.00 86.22  ? 230 ILE E CD1 1 
ATOM   12931 N N   . LEU E 1 285 ? 112.118 139.508 149.832 1.00 79.04  ? 231 LEU E N   1 
ATOM   12932 C CA  . LEU E 1 285 ? 112.342 138.524 150.886 1.00 80.01  ? 231 LEU E CA  1 
ATOM   12933 C C   . LEU E 1 285 ? 113.576 138.872 151.707 1.00 83.60  ? 231 LEU E C   1 
ATOM   12934 O O   . LEU E 1 285 ? 113.568 138.741 152.937 1.00 88.02  ? 231 LEU E O   1 
ATOM   12935 C CB  . LEU E 1 285 ? 112.475 137.123 150.290 1.00 75.20  ? 231 LEU E CB  1 
ATOM   12936 C CG  . LEU E 1 285 ? 111.232 136.531 149.623 1.00 78.17  ? 231 LEU E CG  1 
ATOM   12937 C CD1 . LEU E 1 285 ? 111.437 135.055 149.314 1.00 74.19  ? 231 LEU E CD1 1 
ATOM   12938 C CD2 . LEU E 1 285 ? 109.995 136.742 150.484 1.00 74.38  ? 231 LEU E CD2 1 
ATOM   12939 N N   . ILE E 1 286 ? 114.647 139.314 151.046 1.00 76.36  ? 232 ILE E N   1 
ATOM   12940 C CA  . ILE E 1 286 ? 115.844 139.733 151.768 1.00 77.12  ? 232 ILE E CA  1 
ATOM   12941 C C   . ILE E 1 286 ? 115.534 140.927 152.661 1.00 79.89  ? 232 ILE E C   1 
ATOM   12942 O O   . ILE E 1 286 ? 115.988 140.998 153.810 1.00 83.87  ? 232 ILE E O   1 
ATOM   12943 C CB  . ILE E 1 286 ? 116.986 140.039 150.781 1.00 77.28  ? 232 ILE E CB  1 
ATOM   12944 C CG1 . ILE E 1 286 ? 117.443 138.756 150.086 1.00 75.81  ? 232 ILE E CG1 1 
ATOM   12945 C CG2 . ILE E 1 286 ? 118.151 140.695 151.494 1.00 80.27  ? 232 ILE E CG2 1 
ATOM   12946 C CD1 . ILE E 1 286 ? 117.804 137.644 151.040 1.00 71.97  ? 232 ILE E CD1 1 
ATOM   12947 N N   . THR E 1 287 ? 114.749 141.880 152.153 1.00 77.17  ? 233 THR E N   1 
ATOM   12948 C CA  . THR E 1 287 ? 114.391 143.046 152.958 1.00 79.06  ? 233 THR E CA  1 
ATOM   12949 C C   . THR E 1 287 ? 113.597 142.644 154.197 1.00 82.00  ? 233 THR E C   1 
ATOM   12950 O O   . THR E 1 287 ? 113.855 143.143 155.299 1.00 86.66  ? 233 THR E O   1 
ATOM   12951 C CB  . THR E 1 287 ? 113.595 144.042 152.115 1.00 79.77  ? 233 THR E CB  1 
ATOM   12952 O OG1 . THR E 1 287 ? 114.270 144.262 150.871 1.00 87.35  ? 233 THR E OG1 1 
ATOM   12953 C CG2 . THR E 1 287 ? 113.461 145.366 152.848 1.00 75.01  ? 233 THR E CG2 1 
ATOM   12954 N N   . ILE E 1 288 ? 112.635 141.734 154.041 1.00 80.11  ? 234 ILE E N   1 
ATOM   12955 C CA  . ILE E 1 288 ? 111.828 141.314 155.185 1.00 81.90  ? 234 ILE E CA  1 
ATOM   12956 C C   . ILE E 1 288 ? 112.670 140.515 156.177 1.00 82.40  ? 234 ILE E C   1 
ATOM   12957 O O   . ILE E 1 288 ? 112.519 140.656 157.399 1.00 85.83  ? 234 ILE E O   1 
ATOM   12958 C CB  . ILE E 1 288 ? 110.598 140.522 154.709 1.00 83.05  ? 234 ILE E CB  1 
ATOM   12959 C CG1 . ILE E 1 288 ? 109.746 141.382 153.775 1.00 86.33  ? 234 ILE E CG1 1 
ATOM   12960 C CG2 . ILE E 1 288 ? 109.768 140.065 155.894 1.00 80.83  ? 234 ILE E CG2 1 
ATOM   12961 C CD1 . ILE E 1 288 ? 108.554 140.658 153.193 1.00 95.32  ? 234 ILE E CD1 1 
ATOM   12962 N N   . LEU E 1 289 ? 113.568 139.666 155.675 1.00 77.56  ? 235 LEU E N   1 
ATOM   12963 C CA  . LEU E 1 289 ? 114.459 138.927 156.563 1.00 79.76  ? 235 LEU E CA  1 
ATOM   12964 C C   . LEU E 1 289 ? 115.357 139.875 157.348 1.00 84.74  ? 235 LEU E C   1 
ATOM   12965 O O   . LEU E 1 289 ? 115.647 139.637 158.526 1.00 87.57  ? 235 LEU E O   1 
ATOM   12966 C CB  . LEU E 1 289 ? 115.290 137.928 155.758 1.00 74.78  ? 235 LEU E CB  1 
ATOM   12967 C CG  . LEU E 1 289 ? 116.169 136.958 156.548 1.00 75.16  ? 235 LEU E CG  1 
ATOM   12968 C CD1 . LEU E 1 289 ? 115.343 136.215 157.582 1.00 74.54  ? 235 LEU E CD1 1 
ATOM   12969 C CD2 . LEU E 1 289 ? 116.855 135.979 155.610 1.00 77.43  ? 235 LEU E CD2 1 
ATOM   12970 N N   . SER E 1 290 ? 115.814 140.954 156.707 1.00 82.36  ? 236 SER E N   1 
ATOM   12971 C CA  . SER E 1 290 ? 116.568 141.977 157.424 1.00 79.91  ? 236 SER E CA  1 
ATOM   12972 C C   . SER E 1 290 ? 115.700 142.666 158.468 1.00 81.69  ? 236 SER E C   1 
ATOM   12973 O O   . SER E 1 290 ? 116.178 143.005 159.557 1.00 87.28  ? 236 SER E O   1 
ATOM   12974 C CB  . SER E 1 290 ? 117.135 143.001 156.443 1.00 79.82  ? 236 SER E CB  1 
ATOM   12975 O OG  . SER E 1 290 ? 116.095 143.672 155.756 1.00 88.72  ? 236 SER E OG  1 
ATOM   12976 N N   . TRP E 1 291 ? 114.426 142.902 158.143 1.00 80.96  ? 237 TRP E N   1 
ATOM   12977 C CA  . TRP E 1 291 ? 113.499 143.459 159.125 1.00 84.81  ? 237 TRP E CA  1 
ATOM   12978 C C   . TRP E 1 291 ? 113.405 142.573 160.356 1.00 87.42  ? 237 TRP E C   1 
ATOM   12979 O O   . TRP E 1 291 ? 113.306 143.071 161.484 1.00 86.89  ? 237 TRP E O   1 
ATOM   12980 C CB  . TRP E 1 291 ? 112.108 143.621 158.523 1.00 83.04  ? 237 TRP E CB  1 
ATOM   12981 C CG  . TRP E 1 291 ? 111.993 144.653 157.478 1.00 83.17  ? 237 TRP E CG  1 
ATOM   12982 C CD1 . TRP E 1 291 ? 112.938 145.559 157.103 1.00 83.27  ? 237 TRP E CD1 1 
ATOM   12983 C CD2 . TRP E 1 291 ? 110.852 144.895 156.658 1.00 86.48  ? 237 TRP E CD2 1 
ATOM   12984 N NE1 . TRP E 1 291 ? 112.452 146.353 156.095 1.00 87.20  ? 237 TRP E NE1 1 
ATOM   12985 C CE2 . TRP E 1 291 ? 111.171 145.963 155.804 1.00 90.47  ? 237 TRP E CE2 1 
ATOM   12986 C CE3 . TRP E 1 291 ? 109.586 144.309 156.562 1.00 86.86  ? 237 TRP E CE3 1 
ATOM   12987 C CZ2 . TRP E 1 291 ? 110.275 146.456 154.868 1.00 95.00  ? 237 TRP E CZ2 1 
ATOM   12988 C CZ3 . TRP E 1 291 ? 108.697 144.801 155.632 1.00 93.49  ? 237 TRP E CZ3 1 
ATOM   12989 C CH2 . TRP E 1 291 ? 109.045 145.864 154.796 1.00 96.26  ? 237 TRP E CH2 1 
ATOM   12990 N N   . VAL E 1 292 ? 113.410 141.254 160.152 1.00 88.96  ? 238 VAL E N   1 
ATOM   12991 C CA  . VAL E 1 292 ? 113.269 140.312 161.263 1.00 90.08  ? 238 VAL E CA  1 
ATOM   12992 C C   . VAL E 1 292 ? 114.319 140.568 162.339 1.00 84.94  ? 238 VAL E C   1 
ATOM   12993 O O   . VAL E 1 292 ? 114.099 140.266 163.518 1.00 86.73  ? 238 VAL E O   1 
ATOM   12994 C CB  . VAL E 1 292 ? 113.329 138.861 160.739 1.00 88.93  ? 238 VAL E CB  1 
ATOM   12995 C CG1 . VAL E 1 292 ? 113.236 137.864 161.879 1.00 88.04  ? 238 VAL E CG1 1 
ATOM   12996 C CG2 . VAL E 1 292 ? 112.208 138.614 159.748 1.00 87.67  ? 238 VAL E CG2 1 
ATOM   12997 N N   . SER E 1 293 ? 115.453 141.165 161.967 1.00 80.97  ? 239 SER E N   1 
ATOM   12998 C CA  . SER E 1 293 ? 116.504 141.462 162.934 1.00 86.86  ? 239 SER E CA  1 
ATOM   12999 C C   . SER E 1 293 ? 116.083 142.477 163.987 1.00 91.65  ? 239 SER E C   1 
ATOM   13000 O O   . SER E 1 293 ? 116.774 142.608 165.002 1.00 94.30  ? 239 SER E O   1 
ATOM   13001 C CB  . SER E 1 293 ? 117.752 141.977 162.218 1.00 85.33  ? 239 SER E CB  1 
ATOM   13002 O OG  . SER E 1 293 ? 118.700 142.469 163.149 1.00 77.79  ? 239 SER E OG  1 
ATOM   13003 N N   . PHE E 1 294 ? 114.980 143.198 163.778 1.00 92.10  ? 240 PHE E N   1 
ATOM   13004 C CA  . PHE E 1 294 ? 114.555 144.189 164.761 1.00 92.06  ? 240 PHE E CA  1 
ATOM   13005 C C   . PHE E 1 294 ? 113.942 143.527 165.988 1.00 95.31  ? 240 PHE E C   1 
ATOM   13006 O O   . PHE E 1 294 ? 114.108 144.015 167.111 1.00 99.86  ? 240 PHE E O   1 
ATOM   13007 C CB  . PHE E 1 294 ? 113.565 145.160 164.126 1.00 89.56  ? 240 PHE E CB  1 
ATOM   13008 C CG  . PHE E 1 294 ? 114.161 146.011 163.051 1.00 87.34  ? 240 PHE E CG  1 
ATOM   13009 C CD1 . PHE E 1 294 ? 115.502 146.343 163.078 1.00 86.22  ? 240 PHE E CD1 1 
ATOM   13010 C CD2 . PHE E 1 294 ? 113.380 146.477 162.010 1.00 90.73  ? 240 PHE E CD2 1 
ATOM   13011 C CE1 . PHE E 1 294 ? 116.053 147.126 162.088 1.00 88.21  ? 240 PHE E CE1 1 
ATOM   13012 C CE2 . PHE E 1 294 ? 113.925 147.261 161.018 1.00 92.55  ? 240 PHE E CE2 1 
ATOM   13013 C CZ  . PHE E 1 294 ? 115.264 147.586 161.057 1.00 91.12  ? 240 PHE E CZ  1 
ATOM   13014 N N   . TRP E 1 295 ? 113.230 142.418 165.794 1.00 93.84  ? 241 TRP E N   1 
ATOM   13015 C CA  . TRP E 1 295 ? 112.616 141.700 166.901 1.00 94.33  ? 241 TRP E CA  1 
ATOM   13016 C C   . TRP E 1 295 ? 113.621 140.917 167.735 1.00 92.66  ? 241 TRP E C   1 
ATOM   13017 O O   . TRP E 1 295 ? 113.253 140.402 168.796 1.00 97.36  ? 241 TRP E O   1 
ATOM   13018 C CB  . TRP E 1 295 ? 111.534 140.754 166.374 1.00 91.53  ? 241 TRP E CB  1 
ATOM   13019 C CG  . TRP E 1 295 ? 110.213 141.421 166.143 1.00 90.17  ? 241 TRP E CG  1 
ATOM   13020 C CD1 . TRP E 1 295 ? 109.114 141.354 166.947 1.00 91.07  ? 241 TRP E CD1 1 
ATOM   13021 C CD2 . TRP E 1 295 ? 109.852 142.259 165.038 1.00 95.38  ? 241 TRP E CD2 1 
ATOM   13022 N NE1 . TRP E 1 295 ? 108.090 142.095 166.412 1.00 94.49  ? 241 TRP E NE1 1 
ATOM   13023 C CE2 . TRP E 1 295 ? 108.517 142.661 165.240 1.00 98.42  ? 241 TRP E CE2 1 
ATOM   13024 C CE3 . TRP E 1 295 ? 110.526 142.707 163.898 1.00 96.02  ? 241 TRP E CE3 1 
ATOM   13025 C CZ2 . TRP E 1 295 ? 107.843 143.490 164.345 1.00 100.45 ? 241 TRP E CZ2 1 
ATOM   13026 C CZ3 . TRP E 1 295 ? 109.855 143.530 163.011 1.00 99.41  ? 241 TRP E CZ3 1 
ATOM   13027 C CH2 . TRP E 1 295 ? 108.528 143.913 163.240 1.00 99.22  ? 241 TRP E CH2 1 
ATOM   13028 N N   . ILE E 1 296 ? 114.865 140.809 167.285 1.00 86.45  ? 242 ILE E N   1 
ATOM   13029 C CA  . ILE E 1 296 ? 115.897 140.116 168.045 1.00 88.33  ? 242 ILE E CA  1 
ATOM   13030 C C   . ILE E 1 296 ? 116.380 141.020 169.170 1.00 94.34  ? 242 ILE E C   1 
ATOM   13031 O O   . ILE E 1 296 ? 116.580 142.225 168.978 1.00 97.37  ? 242 ILE E O   1 
ATOM   13032 C CB  . ILE E 1 296 ? 117.056 139.699 167.124 1.00 86.82  ? 242 ILE E CB  1 
ATOM   13033 C CG1 . ILE E 1 296 ? 116.524 138.926 165.916 1.00 81.93  ? 242 ILE E CG1 1 
ATOM   13034 C CG2 . ILE E 1 296 ? 118.063 138.857 167.885 1.00 90.73  ? 242 ILE E CG2 1 
ATOM   13035 C CD1 . ILE E 1 296 ? 115.800 137.651 166.279 1.00 81.42  ? 242 ILE E CD1 1 
ATOM   13036 N N   . ASN E 1 297 ? 116.559 140.441 170.356 1.00 95.16  ? 243 ASN E N   1 
ATOM   13037 C CA  . ASN E 1 297 ? 117.064 141.206 171.486 1.00 101.78 ? 243 ASN E CA  1 
ATOM   13038 C C   . ASN E 1 297 ? 118.489 141.675 171.213 1.00 109.00 ? 243 ASN E C   1 
ATOM   13039 O O   . ASN E 1 297 ? 119.262 141.016 170.513 1.00 109.79 ? 243 ASN E O   1 
ATOM   13040 C CB  . ASN E 1 297 ? 117.017 140.363 172.761 1.00 106.21 ? 243 ASN E CB  1 
ATOM   13041 C CG  . ASN E 1 297 ? 117.475 141.130 173.989 1.00 113.94 ? 243 ASN E CG  1 
ATOM   13042 O OD1 . ASN E 1 297 ? 117.528 142.360 173.984 1.00 117.02 ? 243 ASN E OD1 1 
ATOM   13043 N ND2 . ASN E 1 297 ? 117.803 140.404 175.051 1.00 115.02 ? 243 ASN E ND2 1 
ATOM   13044 N N   . TYR E 1 298 ? 118.835 142.835 171.777 1.00 112.24 ? 244 TYR E N   1 
ATOM   13045 C CA  . TYR E 1 298 ? 120.143 143.431 171.535 1.00 113.74 ? 244 TYR E CA  1 
ATOM   13046 C C   . TYR E 1 298 ? 121.284 142.659 172.184 1.00 112.69 ? 244 TYR E C   1 
ATOM   13047 O O   . TYR E 1 298 ? 122.447 142.949 171.885 1.00 111.69 ? 244 TYR E O   1 
ATOM   13048 C CB  . TYR E 1 298 ? 120.161 144.883 172.020 1.00 112.71 ? 244 TYR E CB  1 
ATOM   13049 C CG  . TYR E 1 298 ? 119.564 145.089 173.395 1.00 115.73 ? 244 TYR E CG  1 
ATOM   13050 C CD1 . TYR E 1 298 ? 118.237 145.469 173.546 1.00 113.39 ? 244 TYR E CD1 1 
ATOM   13051 C CD2 . TYR E 1 298 ? 120.327 144.909 174.541 1.00 117.67 ? 244 TYR E CD2 1 
ATOM   13052 C CE1 . TYR E 1 298 ? 117.687 145.660 174.797 1.00 118.58 ? 244 TYR E CE1 1 
ATOM   13053 C CE2 . TYR E 1 298 ? 119.786 145.099 175.797 1.00 120.37 ? 244 TYR E CE2 1 
ATOM   13054 C CZ  . TYR E 1 298 ? 118.465 145.474 175.919 1.00 123.95 ? 244 TYR E CZ  1 
ATOM   13055 O OH  . TYR E 1 298 ? 117.920 145.664 177.168 1.00 123.03 ? 244 TYR E OH  1 
ATOM   13056 N N   . ASP E 1 299 ? 120.990 141.698 173.062 1.00 110.42 ? 245 ASP E N   1 
ATOM   13057 C CA  . ASP E 1 299 ? 122.061 140.922 173.678 1.00 110.66 ? 245 ASP E CA  1 
ATOM   13058 C C   . ASP E 1 299 ? 122.729 139.997 172.666 1.00 111.29 ? 245 ASP E C   1 
ATOM   13059 O O   . ASP E 1 299 ? 123.955 139.840 172.677 1.00 107.30 ? 245 ASP E O   1 
ATOM   13060 C CB  . ASP E 1 299 ? 121.521 140.127 174.869 1.00 107.76 ? 245 ASP E CB  1 
ATOM   13061 C CG  . ASP E 1 299 ? 120.595 139.001 174.453 1.00 113.42 ? 245 ASP E CG  1 
ATOM   13062 O OD1 . ASP E 1 299 ? 119.907 139.142 173.420 1.00 113.07 ? 245 ASP E OD1 1 
ATOM   13063 O OD2 . ASP E 1 299 ? 120.558 137.972 175.158 1.00 117.57 ? 245 ASP E OD2 1 
ATOM   13064 N N   . ALA E 1 300 ? 121.941 139.379 171.784 1.00 112.49 ? 246 ALA E N   1 
ATOM   13065 C CA  . ALA E 1 300 ? 122.460 138.425 170.804 1.00 105.66 ? 246 ALA E CA  1 
ATOM   13066 C C   . ALA E 1 300 ? 123.053 139.199 169.631 1.00 107.31 ? 246 ALA E C   1 
ATOM   13067 O O   . ALA E 1 300 ? 122.419 139.420 168.596 1.00 108.13 ? 246 ALA E O   1 
ATOM   13068 C CB  . ALA E 1 300 ? 121.364 137.469 170.352 1.00 101.27 ? 246 ALA E CB  1 
ATOM   13069 N N   . SER E 1 301 ? 124.305 139.623 169.809 1.00 105.11 ? 247 SER E N   1 
ATOM   13070 C CA  . SER E 1 301 ? 124.987 140.374 168.760 1.00 102.55 ? 247 SER E CA  1 
ATOM   13071 C C   . SER E 1 301 ? 125.224 139.516 167.522 1.00 102.90 ? 247 SER E C   1 
ATOM   13072 O O   . SER E 1 301 ? 125.071 139.992 166.389 1.00 103.68 ? 247 SER E O   1 
ATOM   13073 C CB  . SER E 1 301 ? 126.310 140.926 169.290 1.00 93.32  ? 247 SER E CB  1 
ATOM   13074 O OG  . SER E 1 301 ? 127.160 139.881 169.729 1.00 94.33  ? 247 SER E OG  1 
ATOM   13075 N N   . ALA E 1 302 ? 125.595 138.248 167.720 1.00 98.01  ? 248 ALA E N   1 
ATOM   13076 C CA  . ALA E 1 302 ? 126.020 137.408 166.605 1.00 93.88  ? 248 ALA E CA  1 
ATOM   13077 C C   . ALA E 1 302 ? 124.898 137.198 165.596 1.00 93.91  ? 248 ALA E C   1 
ATOM   13078 O O   . ALA E 1 302 ? 125.127 137.265 164.383 1.00 92.70  ? 248 ALA E O   1 
ATOM   13079 C CB  . ALA E 1 302 ? 126.527 136.065 167.127 1.00 90.48  ? 248 ALA E CB  1 
ATOM   13080 N N   . ALA E 1 303 ? 123.679 136.942 166.075 1.00 94.49  ? 249 ALA E N   1 
ATOM   13081 C CA  . ALA E 1 303 ? 122.570 136.666 165.166 1.00 93.65  ? 249 ALA E CA  1 
ATOM   13082 C C   . ALA E 1 303 ? 122.244 137.880 164.304 1.00 98.50  ? 249 ALA E C   1 
ATOM   13083 O O   . ALA E 1 303 ? 122.045 137.761 163.090 1.00 99.94  ? 249 ALA E O   1 
ATOM   13084 C CB  . ALA E 1 303 ? 121.341 136.221 165.959 1.00 91.42  ? 249 ALA E CB  1 
ATOM   13085 N N   . ARG E 1 304 ? 122.186 139.062 164.919 1.00 97.96  ? 250 ARG E N   1 
ATOM   13086 C CA  . ARG E 1 304 ? 121.863 140.270 164.167 1.00 96.07  ? 250 ARG E CA  1 
ATOM   13087 C C   . ARG E 1 304 ? 122.981 140.632 163.195 1.00 96.46  ? 250 ARG E C   1 
ATOM   13088 O O   . ARG E 1 304 ? 122.715 141.060 162.062 1.00 92.37  ? 250 ARG E O   1 
ATOM   13089 C CB  . ARG E 1 304 ? 121.575 141.416 165.135 1.00 93.53  ? 250 ARG E CB  1 
ATOM   13090 C CG  . ARG E 1 304 ? 120.544 141.044 166.190 1.00 94.40  ? 250 ARG E CG  1 
ATOM   13091 C CD  . ARG E 1 304 ? 120.228 142.196 167.123 1.00 93.67  ? 250 ARG E CD  1 
ATOM   13092 N NE  . ARG E 1 304 ? 119.559 143.289 166.430 1.00 94.55  ? 250 ARG E NE  1 
ATOM   13093 C CZ  . ARG E 1 304 ? 119.036 144.347 167.034 1.00 91.70  ? 250 ARG E CZ  1 
ATOM   13094 N NH1 . ARG E 1 304 ? 119.071 144.479 168.349 1.00 95.71  ? 250 ARG E NH1 1 
ATOM   13095 N NH2 . ARG E 1 304 ? 118.462 145.295 166.299 1.00 85.99  ? 250 ARG E NH2 1 
ATOM   13096 N N   . VAL E 1 305 ? 124.238 140.452 163.612 1.00 97.16  ? 251 VAL E N   1 
ATOM   13097 C CA  . VAL E 1 305 ? 125.357 140.685 162.703 1.00 95.69  ? 251 VAL E CA  1 
ATOM   13098 C C   . VAL E 1 305 ? 125.273 139.746 161.507 1.00 93.91  ? 251 VAL E C   1 
ATOM   13099 O O   . VAL E 1 305 ? 125.474 140.160 160.357 1.00 97.14  ? 251 VAL E O   1 
ATOM   13100 C CB  . VAL E 1 305 ? 126.695 140.531 163.450 1.00 95.90  ? 251 VAL E CB  1 
ATOM   13101 C CG1 . VAL E 1 305 ? 127.845 140.440 162.465 1.00 96.62  ? 251 VAL E CG1 1 
ATOM   13102 C CG2 . VAL E 1 305 ? 126.909 141.694 164.402 1.00 92.47  ? 251 VAL E CG2 1 
ATOM   13103 N N   . ALA E 1 306 ? 124.972 138.469 161.757 1.00 91.44  ? 252 ALA E N   1 
ATOM   13104 C CA  . ALA E 1 306 ? 124.857 137.505 160.669 1.00 92.82  ? 252 ALA E CA  1 
ATOM   13105 C C   . ALA E 1 306 ? 123.716 137.867 159.729 1.00 91.36  ? 252 ALA E C   1 
ATOM   13106 O O   . ALA E 1 306 ? 123.854 137.755 158.506 1.00 91.79  ? 252 ALA E O   1 
ATOM   13107 C CB  . ALA E 1 306 ? 124.663 136.097 161.230 1.00 95.15  ? 252 ALA E CB  1 
ATOM   13108 N N   . LEU E 1 307 ? 122.578 138.294 160.281 1.00 89.60  ? 253 LEU E N   1 
ATOM   13109 C CA  . LEU E 1 307 ? 121.459 138.700 159.438 1.00 92.93  ? 253 LEU E CA  1 
ATOM   13110 C C   . LEU E 1 307 ? 121.846 139.871 158.547 1.00 94.09  ? 253 LEU E C   1 
ATOM   13111 O O   . LEU E 1 307 ? 121.564 139.870 157.342 1.00 97.13  ? 253 LEU E O   1 
ATOM   13112 C CB  . LEU E 1 307 ? 120.246 139.058 160.297 1.00 88.39  ? 253 LEU E CB  1 
ATOM   13113 C CG  . LEU E 1 307 ? 119.477 137.903 160.936 1.00 91.76  ? 253 LEU E CG  1 
ATOM   13114 C CD1 . LEU E 1 307 ? 118.139 138.390 161.467 1.00 88.41  ? 253 LEU E CD1 1 
ATOM   13115 C CD2 . LEU E 1 307 ? 119.281 136.774 159.940 1.00 91.01  ? 253 LEU E CD2 1 
ATOM   13116 N N   . GLY E 1 308 ? 122.507 140.879 159.121 1.00 89.06  ? 254 GLY E N   1 
ATOM   13117 C CA  . GLY E 1 308 ? 122.927 142.017 158.319 1.00 86.54  ? 254 GLY E CA  1 
ATOM   13118 C C   . GLY E 1 308 ? 123.890 141.624 157.214 1.00 87.79  ? 254 GLY E C   1 
ATOM   13119 O O   . GLY E 1 308 ? 123.728 142.025 156.055 1.00 90.16  ? 254 GLY E O   1 
ATOM   13120 N N   . ILE E 1 309 ? 124.901 140.820 157.559 1.00 86.58  ? 255 ILE E N   1 
ATOM   13121 C CA  . ILE E 1 309 ? 125.881 140.381 156.569 1.00 85.88  ? 255 ILE E CA  1 
ATOM   13122 C C   . ILE E 1 309 ? 125.193 139.627 155.443 1.00 85.46  ? 255 ILE E C   1 
ATOM   13123 O O   . ILE E 1 309 ? 125.408 139.909 154.256 1.00 89.61  ? 255 ILE E O   1 
ATOM   13124 C CB  . ILE E 1 309 ? 126.962 139.508 157.230 1.00 89.78  ? 255 ILE E CB  1 
ATOM   13125 C CG1 . ILE E 1 309 ? 127.794 140.308 158.226 1.00 90.09  ? 255 ILE E CG1 1 
ATOM   13126 C CG2 . ILE E 1 309 ? 127.859 138.887 156.175 1.00 89.28  ? 255 ILE E CG2 1 
ATOM   13127 C CD1 . ILE E 1 309 ? 128.723 139.436 159.034 1.00 90.07  ? 255 ILE E CD1 1 
ATOM   13128 N N   . THR E 1 310 ? 124.360 138.647 155.800 1.00 81.27  ? 256 THR E N   1 
ATOM   13129 C CA  . THR E 1 310 ? 123.708 137.821 154.793 1.00 87.44  ? 256 THR E CA  1 
ATOM   13130 C C   . THR E 1 310 ? 122.824 138.663 153.887 1.00 91.56  ? 256 THR E C   1 
ATOM   13131 O O   . THR E 1 310 ? 122.856 138.510 152.663 1.00 91.60  ? 256 THR E O   1 
ATOM   13132 C CB  . THR E 1 310 ? 122.892 136.714 155.461 1.00 92.53  ? 256 THR E CB  1 
ATOM   13133 O OG1 . THR E 1 310 ? 122.081 137.277 156.498 1.00 94.08  ? 256 THR E OG1 1 
ATOM   13134 C CG2 . THR E 1 310 ? 123.811 135.657 156.051 1.00 97.26  ? 256 THR E CG2 1 
ATOM   13135 N N   . THR E 1 311 ? 122.038 139.573 154.468 1.00 88.60  ? 257 THR E N   1 
ATOM   13136 C CA  . THR E 1 311 ? 121.135 140.382 153.655 1.00 86.61  ? 257 THR E CA  1 
ATOM   13137 C C   . THR E 1 311 ? 121.905 141.275 152.689 1.00 85.60  ? 257 THR E C   1 
ATOM   13138 O O   . THR E 1 311 ? 121.586 141.334 151.494 1.00 86.82  ? 257 THR E O   1 
ATOM   13139 C CB  . THR E 1 311 ? 120.222 141.215 154.552 1.00 85.65  ? 257 THR E CB  1 
ATOM   13140 O OG1 . THR E 1 311 ? 121.006 141.895 155.541 1.00 85.89  ? 257 THR E OG1 1 
ATOM   13141 C CG2 . THR E 1 311 ? 119.200 140.322 155.237 1.00 84.72  ? 257 THR E CG2 1 
ATOM   13142 N N   . VAL E 1 312 ? 122.938 141.965 153.181 1.00 81.79  ? 258 VAL E N   1 
ATOM   13143 C CA  . VAL E 1 312 ? 123.677 142.889 152.320 1.00 79.99  ? 258 VAL E CA  1 
ATOM   13144 C C   . VAL E 1 312 ? 124.384 142.130 151.201 1.00 85.13  ? 258 VAL E C   1 
ATOM   13145 O O   . VAL E 1 312 ? 124.310 142.506 150.020 1.00 90.70  ? 258 VAL E O   1 
ATOM   13146 C CB  . VAL E 1 312 ? 124.665 143.723 153.153 1.00 79.59  ? 258 VAL E CB  1 
ATOM   13147 C CG1 . VAL E 1 312 ? 125.561 144.542 152.245 1.00 82.22  ? 258 VAL E CG1 1 
ATOM   13148 C CG2 . VAL E 1 312 ? 123.910 144.628 154.109 1.00 81.00  ? 258 VAL E CG2 1 
ATOM   13149 N N   . LEU E 1 313 ? 125.072 141.040 151.552 1.00 82.85  ? 259 LEU E N   1 
ATOM   13150 C CA  . LEU E 1 313 ? 125.809 140.297 150.538 1.00 85.56  ? 259 LEU E CA  1 
ATOM   13151 C C   . LEU E 1 313 ? 124.873 139.611 149.552 1.00 88.86  ? 259 LEU E C   1 
ATOM   13152 O O   . LEU E 1 313 ? 125.193 139.518 148.362 1.00 94.95  ? 259 LEU E O   1 
ATOM   13153 C CB  . LEU E 1 313 ? 126.737 139.283 151.201 1.00 84.88  ? 259 LEU E CB  1 
ATOM   13154 C CG  . LEU E 1 313 ? 127.786 139.910 152.119 1.00 80.31  ? 259 LEU E CG  1 
ATOM   13155 C CD1 . LEU E 1 313 ? 128.814 138.882 152.549 1.00 88.77  ? 259 LEU E CD1 1 
ATOM   13156 C CD2 . LEU E 1 313 ? 128.455 141.088 151.436 1.00 75.02  ? 259 LEU E CD2 1 
ATOM   13157 N N   . THR E 1 314 ? 123.711 139.142 150.014 1.00 82.16  ? 260 THR E N   1 
ATOM   13158 C CA  . THR E 1 314 ? 122.737 138.567 149.100 1.00 83.94  ? 260 THR E CA  1 
ATOM   13159 C C   . THR E 1 314 ? 122.187 139.615 148.146 1.00 90.77  ? 260 THR E C   1 
ATOM   13160 O O   . THR E 1 314 ? 121.959 139.320 146.970 1.00 95.77  ? 260 THR E O   1 
ATOM   13161 C CB  . THR E 1 314 ? 121.604 137.908 149.883 1.00 79.70  ? 260 THR E CB  1 
ATOM   13162 O OG1 . THR E 1 314 ? 122.159 137.076 150.908 1.00 82.05  ? 260 THR E OG1 1 
ATOM   13163 C CG2 . THR E 1 314 ? 120.755 137.052 148.959 1.00 80.34  ? 260 THR E CG2 1 
ATOM   13164 N N   . MET E 1 315 ? 121.966 140.840 148.628 1.00 89.23  ? 261 MET E N   1 
ATOM   13165 C CA  . MET E 1 315 ? 121.532 141.910 147.735 1.00 89.58  ? 261 MET E CA  1 
ATOM   13166 C C   . MET E 1 315 ? 122.584 142.188 146.666 1.00 92.24  ? 261 MET E C   1 
ATOM   13167 O O   . MET E 1 315 ? 122.260 142.365 145.483 1.00 97.70  ? 261 MET E O   1 
ATOM   13168 C CB  . MET E 1 315 ? 121.226 143.172 148.542 1.00 83.03  ? 261 MET E CB  1 
ATOM   13169 C CG  . MET E 1 315 ? 120.532 144.263 147.746 1.00 83.78  ? 261 MET E CG  1 
ATOM   13170 S SD  . MET E 1 315 ? 118.951 143.719 147.074 1.00 93.51  ? 261 MET E SD  1 
ATOM   13171 C CE  . MET E 1 315 ? 118.133 143.160 148.565 1.00 82.19  ? 261 MET E CE  1 
ATOM   13172 N N   . THR E 1 316 ? 123.859 142.218 147.063 1.00 88.17  ? 262 THR E N   1 
ATOM   13173 C CA  . THR E 1 316 ? 124.922 142.417 146.077 1.00 89.48  ? 262 THR E CA  1 
ATOM   13174 C C   . THR E 1 316 ? 124.962 141.275 145.062 1.00 96.21  ? 262 THR E C   1 
ATOM   13175 O O   . THR E 1 316 ? 125.135 141.505 143.855 1.00 103.14 ? 262 THR E O   1 
ATOM   13176 C CB  . THR E 1 316 ? 126.274 142.561 146.774 1.00 82.31  ? 262 THR E CB  1 
ATOM   13177 O OG1 . THR E 1 316 ? 126.546 141.383 147.542 1.00 86.57  ? 262 THR E OG1 1 
ATOM   13178 C CG2 . THR E 1 316 ? 126.273 143.771 147.691 1.00 75.43  ? 262 THR E CG2 1 
ATOM   13179 N N   . THR E 1 317 ? 124.797 140.036 145.528 1.00 92.61  ? 263 THR E N   1 
ATOM   13180 C CA  . THR E 1 317 ? 124.820 138.898 144.613 1.00 94.64  ? 263 THR E CA  1 
ATOM   13181 C C   . THR E 1 317 ? 123.625 138.926 143.668 1.00 100.15 ? 263 THR E C   1 
ATOM   13182 O O   . THR E 1 317 ? 123.729 138.517 142.509 1.00 109.88 ? 263 THR E O   1 
ATOM   13183 C CB  . THR E 1 317 ? 124.860 137.582 145.393 1.00 96.10  ? 263 THR E CB  1 
ATOM   13184 O OG1 . THR E 1 317 ? 123.778 137.544 146.330 1.00 98.01  ? 263 THR E OG1 1 
ATOM   13185 C CG2 . THR E 1 317 ? 126.184 137.438 146.131 1.00 97.54  ? 263 THR E CG2 1 
ATOM   13186 N N   . ILE E 1 318 ? 122.475 139.404 144.147 1.00 94.26  ? 264 ILE E N   1 
ATOM   13187 C CA  . ILE E 1 318 ? 121.309 139.550 143.278 1.00 96.03  ? 264 ILE E CA  1 
ATOM   13188 C C   . ILE E 1 318 ? 121.566 140.615 142.219 1.00 105.55 ? 264 ILE E C   1 
ATOM   13189 O O   . ILE E 1 318 ? 121.167 140.469 141.053 1.00 116.15 ? 264 ILE E O   1 
ATOM   13190 C CB  . ILE E 1 318 ? 120.056 139.867 144.115 1.00 92.05  ? 264 ILE E CB  1 
ATOM   13191 C CG1 . ILE E 1 318 ? 119.653 138.651 144.950 1.00 94.77  ? 264 ILE E CG1 1 
ATOM   13192 C CG2 . ILE E 1 318 ? 118.906 140.301 143.223 1.00 94.48  ? 264 ILE E CG2 1 
ATOM   13193 C CD1 . ILE E 1 318 ? 118.509 138.914 145.901 1.00 86.92  ? 264 ILE E CD1 1 
ATOM   13194 N N   . ASN E 1 319 ? 122.229 141.706 142.608 1.00 104.00 ? 265 ASN E N   1 
ATOM   13195 C CA  . ASN E 1 319 ? 122.617 142.722 141.633 1.00 110.75 ? 265 ASN E CA  1 
ATOM   13196 C C   . ASN E 1 319 ? 123.507 142.122 140.550 1.00 115.00 ? 265 ASN E C   1 
ATOM   13197 O O   . ASN E 1 319 ? 123.318 142.381 139.356 1.00 113.67 ? 265 ASN E O   1 
ATOM   13198 C CB  . ASN E 1 319 ? 123.325 143.882 142.334 1.00 113.94 ? 265 ASN E CB  1 
ATOM   13199 C CG  . ASN E 1 319 ? 123.907 144.888 141.358 1.00 125.47 ? 265 ASN E CG  1 
ATOM   13200 O OD1 . ASN E 1 319 ? 123.216 145.797 140.898 1.00 130.02 ? 265 ASN E OD1 1 
ATOM   13201 N ND2 . ASN E 1 319 ? 125.189 144.733 141.043 1.00 125.89 ? 265 ASN E ND2 1 
ATOM   13202 N N   . THR E 1 320 ? 124.481 141.303 140.954 1.00 115.54 ? 266 THR E N   1 
ATOM   13203 C CA  . THR E 1 320 ? 125.341 140.647 139.968 1.00 114.32 ? 266 THR E CA  1 
ATOM   13204 C C   . THR E 1 320 ? 124.549 139.679 139.092 1.00 116.55 ? 266 THR E C   1 
ATOM   13205 O O   . THR E 1 320 ? 124.797 139.573 137.883 1.00 117.69 ? 266 THR E O   1 
ATOM   13206 C CB  . THR E 1 320 ? 126.490 139.917 140.665 1.00 114.47 ? 266 THR E CB  1 
ATOM   13207 O OG1 . THR E 1 320 ? 125.961 138.919 141.546 1.00 118.62 ? 266 THR E OG1 1 
ATOM   13208 C CG2 . THR E 1 320 ? 127.338 140.898 141.461 1.00 113.45 ? 266 THR E CG2 1 
ATOM   13209 N N   . HIS E 1 321 ? 123.601 138.952 139.691 1.00 118.87 ? 267 HIS E N   1 
ATOM   13210 C CA  . HIS E 1 321 ? 122.760 138.031 138.933 1.00 119.86 ? 267 HIS E CA  1 
ATOM   13211 C C   . HIS E 1 321 ? 122.002 138.763 137.836 1.00 121.88 ? 267 HIS E C   1 
ATOM   13212 O O   . HIS E 1 321 ? 121.920 138.291 136.696 1.00 121.33 ? 267 HIS E O   1 
ATOM   13213 C CB  . HIS E 1 321 ? 121.780 137.321 139.869 1.00 115.66 ? 267 HIS E CB  1 
ATOM   13214 C CG  . HIS E 1 321 ? 122.326 136.075 140.491 1.00 120.69 ? 267 HIS E CG  1 
ATOM   13215 N ND1 . HIS E 1 321 ? 123.545 135.537 140.137 1.00 130.41 ? 267 HIS E ND1 1 
ATOM   13216 C CD2 . HIS E 1 321 ? 121.815 135.256 141.440 1.00 119.46 ? 267 HIS E CD2 1 
ATOM   13217 C CE1 . HIS E 1 321 ? 123.762 134.442 140.843 1.00 133.87 ? 267 HIS E CE1 1 
ATOM   13218 N NE2 . HIS E 1 321 ? 122.728 134.250 141.642 1.00 128.87 ? 267 HIS E NE2 1 
ATOM   13219 N N   . LEU E 1 322 ? 121.429 139.919 138.171 1.00 122.07 ? 268 LEU E N   1 
ATOM   13220 C CA  . LEU E 1 322 ? 120.766 140.732 137.157 1.00 123.35 ? 268 LEU E CA  1 
ATOM   13221 C C   . LEU E 1 322 ? 121.760 141.220 136.110 1.00 123.96 ? 268 LEU E C   1 
ATOM   13222 O O   . LEU E 1 322 ? 121.474 141.208 134.907 1.00 116.81 ? 268 LEU E O   1 
ATOM   13223 C CB  . LEU E 1 322 ? 120.059 141.917 137.809 1.00 120.68 ? 268 LEU E CB  1 
ATOM   13224 C CG  . LEU E 1 322 ? 119.474 142.906 136.800 1.00 116.47 ? 268 LEU E CG  1 
ATOM   13225 C CD1 . LEU E 1 322 ? 118.109 142.442 136.310 1.00 106.17 ? 268 LEU E CD1 1 
ATOM   13226 C CD2 . LEU E 1 322 ? 119.406 144.298 137.393 1.00 108.38 ? 268 LEU E CD2 1 
ATOM   13227 N N   . ARG E 1 323 ? 122.943 141.651 136.557 1.00 125.85 ? 269 ARG E N   1 
ATOM   13228 C CA  . ARG E 1 323 ? 123.933 142.209 135.639 1.00 127.11 ? 269 ARG E CA  1 
ATOM   13229 C C   . ARG E 1 323 ? 124.396 141.181 134.615 1.00 126.11 ? 269 ARG E C   1 
ATOM   13230 O O   . ARG E 1 323 ? 124.779 141.539 133.495 1.00 118.70 ? 269 ARG E O   1 
ATOM   13231 C CB  . ARG E 1 323 ? 125.126 142.748 136.426 1.00 120.18 ? 269 ARG E CB  1 
ATOM   13232 C CG  . ARG E 1 323 ? 124.964 144.182 136.872 1.00 112.46 ? 269 ARG E CG  1 
ATOM   13233 C CD  . ARG E 1 323 ? 124.840 145.094 135.670 1.00 114.13 ? 269 ARG E CD  1 
ATOM   13234 N NE  . ARG E 1 323 ? 124.659 146.484 136.063 1.00 114.88 ? 269 ARG E NE  1 
ATOM   13235 C CZ  . ARG E 1 323 ? 123.491 147.018 136.391 1.00 112.01 ? 269 ARG E CZ  1 
ATOM   13236 N NH1 . ARG E 1 323 ? 122.380 146.301 136.392 1.00 110.35 ? 269 ARG E NH1 1 
ATOM   13237 N NH2 . ARG E 1 323 ? 123.439 148.303 136.729 1.00 112.23 ? 269 ARG E NH2 1 
ATOM   13238 N N   . GLU E 1 324 ? 124.367 139.901 134.977 1.00 127.02 ? 270 GLU E N   1 
ATOM   13239 C CA  . GLU E 1 324 ? 124.897 138.866 134.094 1.00 130.72 ? 270 GLU E CA  1 
ATOM   13240 C C   . GLU E 1 324 ? 123.989 138.568 132.902 1.00 129.56 ? 270 GLU E C   1 
ATOM   13241 O O   . GLU E 1 324 ? 124.201 137.575 132.200 1.00 129.58 ? 270 GLU E O   1 
ATOM   13242 C CB  . GLU E 1 324 ? 125.148 137.575 134.878 1.00 133.44 ? 270 GLU E CB  1 
ATOM   13243 C CG  . GLU E 1 324 ? 126.292 137.661 135.873 1.00 134.54 ? 270 GLU E CG  1 
ATOM   13244 C CD  . GLU E 1 324 ? 126.509 136.364 136.628 1.00 133.67 ? 270 GLU E CD  1 
ATOM   13245 O OE1 . GLU E 1 324 ? 126.468 135.289 135.994 1.00 136.47 ? 270 GLU E OE1 1 
ATOM   13246 O OE2 . GLU E 1 324 ? 126.715 136.420 137.859 1.00 128.61 ? 270 GLU E OE2 1 
ATOM   13247 N N   . THR E 1 325 ? 122.977 139.408 132.657 1.00 127.68 ? 271 THR E N   1 
ATOM   13248 C CA  . THR E 1 325 ? 122.012 139.112 131.604 1.00 125.25 ? 271 THR E CA  1 
ATOM   13249 C C   . THR E 1 325 ? 121.841 140.229 130.576 1.00 118.46 ? 271 THR E C   1 
ATOM   13250 O O   . THR E 1 325 ? 121.001 140.091 129.678 1.00 109.93 ? 271 THR E O   1 
ATOM   13251 C CB  . THR E 1 325 ? 120.640 138.781 132.215 1.00 122.80 ? 271 THR E CB  1 
ATOM   13252 O OG1 . THR E 1 325 ? 120.259 139.812 133.135 1.00 112.90 ? 271 THR E OG1 1 
ATOM   13253 C CG2 . THR E 1 325 ? 120.681 137.444 132.943 1.00 119.33 ? 271 THR E CG2 1 
ATOM   13254 N N   . LEU E 1 326 ? 122.597 141.316 130.661 1.00 118.78 ? 272 LEU E N   1 
ATOM   13255 C CA  . LEU E 1 326 ? 122.343 142.494 129.846 1.00 112.64 ? 272 LEU E CA  1 
ATOM   13256 C C   . LEU E 1 326 ? 123.646 143.039 129.284 1.00 109.17 ? 272 LEU E C   1 
ATOM   13257 O O   . LEU E 1 326 ? 124.728 142.733 129.797 1.00 113.83 ? 272 LEU E O   1 
ATOM   13258 C CB  . LEU E 1 326 ? 121.633 143.579 130.665 1.00 104.47 ? 272 LEU E CB  1 
ATOM   13259 C CG  . LEU E 1 326 ? 120.206 143.227 131.076 1.00 99.75  ? 272 LEU E CG  1 
ATOM   13260 C CD1 . LEU E 1 326 ? 119.831 143.966 132.340 1.00 98.26  ? 272 LEU E CD1 1 
ATOM   13261 C CD2 . LEU E 1 326 ? 119.238 143.553 129.950 1.00 89.34  ? 272 LEU E CD2 1 
ATOM   13262 N N   . PRO E 1 327 ? 123.574 143.850 128.217 1.00 100.13 ? 273 PRO E N   1 
ATOM   13263 C CA  . PRO E 1 327 ? 124.784 144.516 127.716 1.00 98.23  ? 273 PRO E CA  1 
ATOM   13264 C C   . PRO E 1 327 ? 125.288 145.596 128.661 1.00 97.90  ? 273 PRO E C   1 
ATOM   13265 O O   . PRO E 1 327 ? 124.692 145.844 129.713 1.00 95.28  ? 273 PRO E O   1 
ATOM   13266 C CB  . PRO E 1 327 ? 124.330 145.108 126.376 1.00 91.26  ? 273 PRO E CB  1 
ATOM   13267 C CG  . PRO E 1 327 ? 122.857 145.253 126.508 1.00 90.86  ? 273 PRO E CG  1 
ATOM   13268 C CD  . PRO E 1 327 ? 122.416 144.087 127.339 1.00 92.71  ? 273 PRO E CD  1 
ATOM   13269 N N   . LYS E 1 328 ? 126.386 146.249 128.285 1.00 92.80  ? 274 LYS E N   1 
ATOM   13270 C CA  . LYS E 1 328 ? 127.071 147.198 129.163 1.00 85.23  ? 274 LYS E CA  1 
ATOM   13271 C C   . LYS E 1 328 ? 126.604 148.632 128.899 1.00 84.84  ? 274 LYS E C   1 
ATOM   13272 O O   . LYS E 1 328 ? 127.374 149.514 128.522 1.00 83.67  ? 274 LYS E O   1 
ATOM   13273 C CB  . LYS E 1 328 ? 128.579 147.064 128.992 1.00 79.32  ? 274 LYS E CB  1 
ATOM   13274 C CG  . LYS E 1 328 ? 129.087 145.652 129.218 1.00 81.00  ? 274 LYS E CG  1 
ATOM   13275 C CD  . LYS E 1 328 ? 130.513 145.485 128.730 1.00 86.80  ? 274 LYS E CD  1 
ATOM   13276 C CE  . LYS E 1 328 ? 130.959 144.037 128.839 1.00 92.55  ? 274 LYS E CE  1 
ATOM   13277 N NZ  . LYS E 1 328 ? 132.312 143.826 128.259 1.00 95.05  ? 274 LYS E NZ  1 
ATOM   13278 N N   . ILE E 1 329 ? 125.308 148.851 129.103 1.00 83.70  ? 275 ILE E N   1 
ATOM   13279 C CA  . ILE E 1 329 ? 124.714 150.182 128.983 1.00 82.83  ? 275 ILE E CA  1 
ATOM   13280 C C   . ILE E 1 329 ? 125.213 151.064 130.122 1.00 83.13  ? 275 ILE E C   1 
ATOM   13281 O O   . ILE E 1 329 ? 125.465 150.563 131.227 1.00 88.49  ? 275 ILE E O   1 
ATOM   13282 C CB  . ILE E 1 329 ? 123.180 150.106 128.977 1.00 78.77  ? 275 ILE E CB  1 
ATOM   13283 C CG1 . ILE E 1 329 ? 122.691 149.241 130.138 1.00 79.91  ? 275 ILE E CG1 1 
ATOM   13284 C CG2 . ILE E 1 329 ? 122.679 149.572 127.646 1.00 85.42  ? 275 ILE E CG2 1 
ATOM   13285 C CD1 . ILE E 1 329 ? 121.195 149.113 130.205 1.00 82.89  ? 275 ILE E CD1 1 
ATOM   13286 N N   . PRO E 1 330 ? 125.366 152.373 129.908 1.00 82.25  ? 276 PRO E N   1 
ATOM   13287 C CA  . PRO E 1 330 ? 125.923 153.232 130.961 1.00 84.23  ? 276 PRO E CA  1 
ATOM   13288 C C   . PRO E 1 330 ? 124.884 153.789 131.923 1.00 84.64  ? 276 PRO E C   1 
ATOM   13289 O O   . PRO E 1 330 ? 125.222 154.163 133.049 1.00 84.71  ? 276 PRO E O   1 
ATOM   13290 C CB  . PRO E 1 330 ? 126.587 154.355 130.159 1.00 87.46  ? 276 PRO E CB  1 
ATOM   13291 C CG  . PRO E 1 330 ? 125.712 154.488 128.955 1.00 84.05  ? 276 PRO E CG  1 
ATOM   13292 C CD  . PRO E 1 330 ? 125.197 153.100 128.638 1.00 80.90  ? 276 PRO E CD  1 
ATOM   13293 N N   . TYR E 1 331 ? 123.624 153.854 131.499 1.00 86.92  ? 277 TYR E N   1 
ATOM   13294 C CA  . TYR E 1 331 ? 122.593 154.499 132.296 1.00 82.10  ? 277 TYR E CA  1 
ATOM   13295 C C   . TYR E 1 331 ? 122.010 153.527 133.321 1.00 80.06  ? 277 TYR E C   1 
ATOM   13296 O O   . TYR E 1 331 ? 122.355 152.344 133.369 1.00 77.39  ? 277 TYR E O   1 
ATOM   13297 C CB  . TYR E 1 331 ? 121.504 155.077 131.395 1.00 78.05  ? 277 TYR E CB  1 
ATOM   13298 C CG  . TYR E 1 331 ? 121.047 154.152 130.292 1.00 77.45  ? 277 TYR E CG  1 
ATOM   13299 C CD1 . TYR E 1 331 ? 120.129 153.144 130.541 1.00 75.02  ? 277 TYR E CD1 1 
ATOM   13300 C CD2 . TYR E 1 331 ? 121.523 154.299 128.997 1.00 81.51  ? 277 TYR E CD2 1 
ATOM   13301 C CE1 . TYR E 1 331 ? 119.706 152.302 129.536 1.00 78.42  ? 277 TYR E CE1 1 
ATOM   13302 C CE2 . TYR E 1 331 ? 121.105 153.462 127.985 1.00 85.17  ? 277 TYR E CE2 1 
ATOM   13303 C CZ  . TYR E 1 331 ? 120.196 152.465 128.260 1.00 84.25  ? 277 TYR E CZ  1 
ATOM   13304 O OH  . TYR E 1 331 ? 119.775 151.626 127.254 1.00 84.42  ? 277 TYR E OH  1 
ATOM   13305 N N   . VAL E 1 332 ? 121.115 154.041 134.160 1.00 79.96  ? 278 VAL E N   1 
ATOM   13306 C CA  . VAL E 1 332 ? 120.541 153.291 135.270 1.00 75.34  ? 278 VAL E CA  1 
ATOM   13307 C C   . VAL E 1 332 ? 119.157 152.802 134.873 1.00 72.27  ? 278 VAL E C   1 
ATOM   13308 O O   . VAL E 1 332 ? 118.315 153.589 134.423 1.00 73.15  ? 278 VAL E O   1 
ATOM   13309 C CB  . VAL E 1 332 ? 120.472 154.149 136.544 1.00 71.95  ? 278 VAL E CB  1 
ATOM   13310 C CG1 . VAL E 1 332 ? 120.129 153.283 137.744 1.00 74.23  ? 278 VAL E CG1 1 
ATOM   13311 C CG2 . VAL E 1 332 ? 121.784 154.882 136.762 1.00 67.91  ? 278 VAL E CG2 1 
ATOM   13312 N N   . LYS E 1 333 ? 118.921 151.506 135.036 0.50 70.58  ? 279 LYS E N   1 
ATOM   13313 C CA  . LYS E 1 333 ? 117.630 150.911 134.740 0.50 69.65  ? 279 LYS E CA  1 
ATOM   13314 C C   . LYS E 1 333 ? 116.712 150.988 135.959 0.50 72.60  ? 279 LYS E C   1 
ATOM   13315 O O   . LYS E 1 333 ? 117.140 151.279 137.076 0.50 76.94  ? 279 LYS E O   1 
ATOM   13316 C CB  . LYS E 1 333 ? 117.807 149.463 134.291 1.00 68.87  ? 279 LYS E CB  1 
ATOM   13317 C CG  . LYS E 1 333 ? 118.694 149.307 133.071 1.00 70.72  ? 279 LYS E CG  1 
ATOM   13318 C CD  . LYS E 1 333 ? 118.923 147.847 132.738 1.00 70.63  ? 279 LYS E CD  1 
ATOM   13319 C CE  . LYS E 1 333 ? 119.906 147.221 133.705 1.00 77.21  ? 279 LYS E CE  1 
ATOM   13320 N NZ  . LYS E 1 333 ? 121.239 147.875 133.633 1.00 76.84  ? 279 LYS E NZ  1 
ATOM   13321 N N   . ALA E 1 334 ? 115.425 150.721 135.725 1.00 67.11  ? 280 ALA E N   1 
ATOM   13322 C CA  . ALA E 1 334 ? 114.460 150.727 136.820 1.00 74.62  ? 280 ALA E CA  1 
ATOM   13323 C C   . ALA E 1 334 ? 114.762 149.626 137.829 1.00 77.41  ? 280 ALA E C   1 
ATOM   13324 O O   . ALA E 1 334 ? 114.693 149.847 139.045 1.00 84.72  ? 280 ALA E O   1 
ATOM   13325 C CB  . ALA E 1 334 ? 113.043 150.575 136.273 1.00 73.93  ? 280 ALA E CB  1 
ATOM   13326 N N   . ILE E 1 335 ? 115.097 148.431 137.341 1.00 70.31  ? 281 ILE E N   1 
ATOM   13327 C CA  . ILE E 1 335 ? 115.424 147.330 138.239 1.00 67.49  ? 281 ILE E CA  1 
ATOM   13328 C C   . ILE E 1 335 ? 116.673 147.660 139.046 1.00 74.13  ? 281 ILE E C   1 
ATOM   13329 O O   . ILE E 1 335 ? 116.779 147.307 140.227 1.00 84.68  ? 281 ILE E O   1 
ATOM   13330 C CB  . ILE E 1 335 ? 115.574 146.021 137.441 1.00 69.35  ? 281 ILE E CB  1 
ATOM   13331 C CG1 . ILE E 1 335 ? 116.024 144.877 138.350 1.00 75.47  ? 281 ILE E CG1 1 
ATOM   13332 C CG2 . ILE E 1 335 ? 116.528 146.210 136.273 1.00 72.81  ? 281 ILE E CG2 1 
ATOM   13333 C CD1 . ILE E 1 335 ? 115.059 144.570 139.470 1.00 82.90  ? 281 ILE E CD1 1 
ATOM   13334 N N   . ASP E 1 336 ? 117.629 148.361 138.431 1.00 70.96  ? 282 ASP E N   1 
ATOM   13335 C CA  . ASP E 1 336 ? 118.797 148.823 139.174 1.00 72.88  ? 282 ASP E CA  1 
ATOM   13336 C C   . ASP E 1 336 ? 118.394 149.785 140.281 1.00 76.39  ? 282 ASP E C   1 
ATOM   13337 O O   . ASP E 1 336 ? 118.929 149.724 141.393 1.00 81.93  ? 282 ASP E O   1 
ATOM   13338 C CB  . ASP E 1 336 ? 119.794 149.494 138.231 1.00 80.68  ? 282 ASP E CB  1 
ATOM   13339 C CG  . ASP E 1 336 ? 120.391 148.531 137.233 1.00 96.57  ? 282 ASP E CG  1 
ATOM   13340 O OD1 . ASP E 1 336 ? 120.445 147.320 137.532 1.00 98.48  ? 282 ASP E OD1 1 
ATOM   13341 O OD2 . ASP E 1 336 ? 120.817 148.987 136.152 1.00 104.31 ? 282 ASP E OD2 1 
ATOM   13342 N N   . MET E 1 337 ? 117.452 150.686 139.992 1.00 77.04  ? 283 MET E N   1 
ATOM   13343 C CA  . MET E 1 337 ? 116.972 151.613 141.011 1.00 78.86  ? 283 MET E CA  1 
ATOM   13344 C C   . MET E 1 337 ? 116.319 150.869 142.170 1.00 76.42  ? 283 MET E C   1 
ATOM   13345 O O   . MET E 1 337 ? 116.547 151.201 143.340 1.00 80.67  ? 283 MET E O   1 
ATOM   13346 C CB  . MET E 1 337 ? 115.990 152.606 140.389 1.00 75.78  ? 283 MET E CB  1 
ATOM   13347 C CG  . MET E 1 337 ? 115.540 153.711 141.327 1.00 80.21  ? 283 MET E CG  1 
ATOM   13348 S SD  . MET E 1 337 ? 116.865 154.873 141.701 1.00 90.18  ? 283 MET E SD  1 
ATOM   13349 C CE  . MET E 1 337 ? 117.244 155.482 140.061 1.00 79.59  ? 283 MET E CE  1 
ATOM   13350 N N   . TYR E 1 338 ? 115.506 149.855 141.865 1.00 71.19  ? 284 TYR E N   1 
ATOM   13351 C CA  . TYR E 1 338 ? 114.856 149.100 142.932 1.00 72.38  ? 284 TYR E CA  1 
ATOM   13352 C C   . TYR E 1 338 ? 115.871 148.323 143.762 1.00 73.27  ? 284 TYR E C   1 
ATOM   13353 O O   . TYR E 1 338 ? 115.746 148.244 144.991 1.00 78.22  ? 284 TYR E O   1 
ATOM   13354 C CB  . TYR E 1 338 ? 113.803 148.157 142.357 1.00 75.56  ? 284 TYR E CB  1 
ATOM   13355 C CG  . TYR E 1 338 ? 112.932 147.527 143.418 1.00 78.25  ? 284 TYR E CG  1 
ATOM   13356 C CD1 . TYR E 1 338 ? 111.904 148.244 144.011 1.00 80.76  ? 284 TYR E CD1 1 
ATOM   13357 C CD2 . TYR E 1 338 ? 113.141 146.219 143.831 1.00 74.98  ? 284 TYR E CD2 1 
ATOM   13358 C CE1 . TYR E 1 338 ? 111.107 147.678 144.982 1.00 82.67  ? 284 TYR E CE1 1 
ATOM   13359 C CE2 . TYR E 1 338 ? 112.345 145.643 144.802 1.00 81.53  ? 284 TYR E CE2 1 
ATOM   13360 C CZ  . TYR E 1 338 ? 111.331 146.379 145.374 1.00 87.12  ? 284 TYR E CZ  1 
ATOM   13361 O OH  . TYR E 1 338 ? 110.533 145.817 146.343 1.00 93.05  ? 284 TYR E OH  1 
ATOM   13362 N N   . LEU E 1 339 ? 116.875 147.731 143.110 1.00 71.51  ? 285 LEU E N   1 
ATOM   13363 C CA  . LEU E 1 339 ? 117.919 147.031 143.852 1.00 70.10  ? 285 LEU E CA  1 
ATOM   13364 C C   . LEU E 1 339 ? 118.696 147.993 144.741 1.00 73.96  ? 285 LEU E C   1 
ATOM   13365 O O   . LEU E 1 339 ? 119.044 147.656 145.879 1.00 76.24  ? 285 LEU E O   1 
ATOM   13366 C CB  . LEU E 1 339 ? 118.861 146.308 142.891 1.00 69.97  ? 285 LEU E CB  1 
ATOM   13367 C CG  . LEU E 1 339 ? 118.262 145.156 142.084 1.00 72.59  ? 285 LEU E CG  1 
ATOM   13368 C CD1 . LEU E 1 339 ? 119.333 144.470 141.254 1.00 83.41  ? 285 LEU E CD1 1 
ATOM   13369 C CD2 . LEU E 1 339 ? 117.573 144.162 143.001 1.00 73.66  ? 285 LEU E CD2 1 
ATOM   13370 N N   . MET E 1 340 ? 118.977 149.197 144.239 1.00 75.73  ? 286 MET E N   1 
ATOM   13371 C CA  . MET E 1 340 ? 119.650 150.201 145.055 1.00 75.93  ? 286 MET E CA  1 
ATOM   13372 C C   . MET E 1 340 ? 118.803 150.584 146.261 1.00 74.99  ? 286 MET E C   1 
ATOM   13373 O O   . MET E 1 340 ? 119.324 150.742 147.369 1.00 78.09  ? 286 MET E O   1 
ATOM   13374 C CB  . MET E 1 340 ? 119.970 151.433 144.210 1.00 77.93  ? 286 MET E CB  1 
ATOM   13375 C CG  . MET E 1 340 ? 120.657 152.552 144.974 1.00 86.53  ? 286 MET E CG  1 
ATOM   13376 S SD  . MET E 1 340 ? 122.260 152.052 145.630 1.00 118.53 ? 286 MET E SD  1 
ATOM   13377 C CE  . MET E 1 340 ? 122.781 153.556 146.447 1.00 82.28  ? 286 MET E CE  1 
ATOM   13378 N N   . GLY E 1 341 ? 117.491 150.730 146.066 1.00 70.48  ? 287 GLY E N   1 
ATOM   13379 C CA  . GLY E 1 341 ? 116.618 151.035 147.190 1.00 74.22  ? 287 GLY E CA  1 
ATOM   13380 C C   . GLY E 1 341 ? 116.600 149.933 148.235 1.00 79.56  ? 287 GLY E C   1 
ATOM   13381 O O   . GLY E 1 341 ? 116.654 150.201 149.441 1.00 81.43  ? 287 GLY E O   1 
ATOM   13382 N N   . CYS E 1 342 ? 116.520 148.677 147.788 1.00 76.85  ? 288 CYS E N   1 
ATOM   13383 C CA  . CYS E 1 342 ? 116.544 147.559 148.728 1.00 71.09  ? 288 CYS E CA  1 
ATOM   13384 C C   . CYS E 1 342 ? 117.865 147.504 149.484 1.00 71.35  ? 288 CYS E C   1 
ATOM   13385 O O   . CYS E 1 342 ? 117.891 147.234 150.694 1.00 76.96  ? 288 CYS E O   1 
ATOM   13386 C CB  . CYS E 1 342 ? 116.291 146.245 147.992 1.00 76.18  ? 288 CYS E CB  1 
ATOM   13387 S SG  . CYS E 1 342 ? 114.572 145.980 147.521 1.00 99.35  ? 288 CYS E SG  1 
ATOM   13388 N N   . PHE E 1 343 ? 118.976 147.754 148.787 1.00 70.68  ? 289 PHE E N   1 
ATOM   13389 C CA  . PHE E 1 343 ? 120.266 147.799 149.462 1.00 70.73  ? 289 PHE E CA  1 
ATOM   13390 C C   . PHE E 1 343 ? 120.305 148.922 150.487 1.00 70.41  ? 289 PHE E C   1 
ATOM   13391 O O   . PHE E 1 343 ? 120.859 148.757 151.579 1.00 74.95  ? 289 PHE E O   1 
ATOM   13392 C CB  . PHE E 1 343 ? 121.399 147.961 148.450 1.00 69.28  ? 289 PHE E CB  1 
ATOM   13393 C CG  . PHE E 1 343 ? 122.748 148.111 149.086 1.00 72.78  ? 289 PHE E CG  1 
ATOM   13394 C CD1 . PHE E 1 343 ? 123.504 146.997 149.402 1.00 78.99  ? 289 PHE E CD1 1 
ATOM   13395 C CD2 . PHE E 1 343 ? 123.251 149.365 149.386 1.00 75.28  ? 289 PHE E CD2 1 
ATOM   13396 C CE1 . PHE E 1 343 ? 124.742 147.132 149.997 1.00 82.22  ? 289 PHE E CE1 1 
ATOM   13397 C CE2 . PHE E 1 343 ? 124.481 149.506 149.983 1.00 81.53  ? 289 PHE E CE2 1 
ATOM   13398 C CZ  . PHE E 1 343 ? 125.230 148.387 150.289 1.00 84.20  ? 289 PHE E CZ  1 
ATOM   13399 N N   . VAL E 1 344 ? 119.733 150.078 150.148 1.00 67.66  ? 290 VAL E N   1 
ATOM   13400 C CA  . VAL E 1 344 ? 119.684 151.186 151.097 1.00 70.03  ? 290 VAL E CA  1 
ATOM   13401 C C   . VAL E 1 344 ? 118.920 150.779 152.348 1.00 71.86  ? 290 VAL E C   1 
ATOM   13402 O O   . VAL E 1 344 ? 119.359 151.043 153.473 1.00 74.26  ? 290 VAL E O   1 
ATOM   13403 C CB  . VAL E 1 344 ? 119.068 152.432 150.435 1.00 66.93  ? 290 VAL E CB  1 
ATOM   13404 C CG1 . VAL E 1 344 ? 118.679 153.455 151.486 1.00 70.46  ? 290 VAL E CG1 1 
ATOM   13405 C CG2 . VAL E 1 344 ? 120.048 153.039 149.452 1.00 68.99  ? 290 VAL E CG2 1 
ATOM   13406 N N   . PHE E 1 345 ? 117.773 150.120 152.176 1.00 68.26  ? 291 PHE E N   1 
ATOM   13407 C CA  . PHE E 1 345 ? 116.971 149.731 153.335 1.00 68.19  ? 291 PHE E CA  1 
ATOM   13408 C C   . PHE E 1 345 ? 117.706 148.718 154.210 1.00 72.69  ? 291 PHE E C   1 
ATOM   13409 O O   . PHE E 1 345 ? 117.726 148.843 155.443 1.00 79.25  ? 291 PHE E O   1 
ATOM   13410 C CB  . PHE E 1 345 ? 115.619 149.179 152.885 1.00 74.02  ? 291 PHE E CB  1 
ATOM   13411 C CG  . PHE E 1 345 ? 114.599 150.242 152.598 1.00 79.79  ? 291 PHE E CG  1 
ATOM   13412 C CD1 . PHE E 1 345 ? 114.081 151.017 153.622 1.00 79.37  ? 291 PHE E CD1 1 
ATOM   13413 C CD2 . PHE E 1 345 ? 114.151 150.463 151.307 1.00 84.94  ? 291 PHE E CD2 1 
ATOM   13414 C CE1 . PHE E 1 345 ? 113.142 151.994 153.363 1.00 82.91  ? 291 PHE E CE1 1 
ATOM   13415 C CE2 . PHE E 1 345 ? 113.212 151.439 151.043 1.00 86.73  ? 291 PHE E CE2 1 
ATOM   13416 C CZ  . PHE E 1 345 ? 112.708 152.206 152.072 1.00 85.68  ? 291 PHE E CZ  1 
ATOM   13417 N N   . VAL E 1 346 ? 118.326 147.706 153.595 1.00 67.33  ? 292 VAL E N   1 
ATOM   13418 C CA  . VAL E 1 346 ? 118.999 146.689 154.402 1.00 67.32  ? 292 VAL E CA  1 
ATOM   13419 C C   . VAL E 1 346 ? 120.229 147.276 155.093 1.00 70.75  ? 292 VAL E C   1 
ATOM   13420 O O   . VAL E 1 346 ? 120.524 146.948 156.252 1.00 75.00  ? 292 VAL E O   1 
ATOM   13421 C CB  . VAL E 1 346 ? 119.345 145.449 153.554 1.00 65.03  ? 292 VAL E CB  1 
ATOM   13422 C CG1 . VAL E 1 346 ? 118.079 144.835 152.983 1.00 70.53  ? 292 VAL E CG1 1 
ATOM   13423 C CG2 . VAL E 1 346 ? 120.317 145.788 152.447 1.00 72.11  ? 292 VAL E CG2 1 
ATOM   13424 N N   . PHE E 1 347 ? 120.953 148.167 154.410 1.00 70.57  ? 293 PHE E N   1 
ATOM   13425 C CA  . PHE E 1 347 ? 122.099 148.816 155.033 1.00 71.87  ? 293 PHE E CA  1 
ATOM   13426 C C   . PHE E 1 347 ? 121.663 149.707 156.187 1.00 76.32  ? 293 PHE E C   1 
ATOM   13427 O O   . PHE E 1 347 ? 122.346 149.778 157.215 1.00 81.09  ? 293 PHE E O   1 
ATOM   13428 C CB  . PHE E 1 347 ? 122.876 149.620 153.993 1.00 73.94  ? 293 PHE E CB  1 
ATOM   13429 C CG  . PHE E 1 347 ? 124.346 149.702 154.271 1.00 78.44  ? 293 PHE E CG  1 
ATOM   13430 C CD1 . PHE E 1 347 ? 124.867 150.737 155.028 1.00 74.89  ? 293 PHE E CD1 1 
ATOM   13431 C CD2 . PHE E 1 347 ? 125.209 148.740 153.775 1.00 80.84  ? 293 PHE E CD2 1 
ATOM   13432 C CE1 . PHE E 1 347 ? 126.223 150.811 155.283 1.00 78.81  ? 293 PHE E CE1 1 
ATOM   13433 C CE2 . PHE E 1 347 ? 126.564 148.808 154.027 1.00 83.36  ? 293 PHE E CE2 1 
ATOM   13434 C CZ  . PHE E 1 347 ? 127.072 149.845 154.782 1.00 85.55  ? 293 PHE E CZ  1 
ATOM   13435 N N   . LEU E 1 348 ? 120.531 150.401 156.035 1.00 73.76  ? 294 LEU E N   1 
ATOM   13436 C CA  . LEU E 1 348 ? 120.009 151.207 157.131 1.00 74.94  ? 294 LEU E CA  1 
ATOM   13437 C C   . LEU E 1 348 ? 119.646 150.339 158.326 1.00 78.70  ? 294 LEU E C   1 
ATOM   13438 O O   . LEU E 1 348 ? 119.906 150.716 159.473 1.00 82.42  ? 294 LEU E O   1 
ATOM   13439 C CB  . LEU E 1 348 ? 118.797 152.014 156.670 1.00 78.45  ? 294 LEU E CB  1 
ATOM   13440 C CG  . LEU E 1 348 ? 119.085 153.244 155.811 1.00 83.26  ? 294 LEU E CG  1 
ATOM   13441 C CD1 . LEU E 1 348 ? 117.829 154.083 155.644 1.00 85.66  ? 294 LEU E CD1 1 
ATOM   13442 C CD2 . LEU E 1 348 ? 120.208 154.067 156.419 1.00 86.14  ? 294 LEU E CD2 1 
ATOM   13443 N N   . ALA E 1 349 ? 119.039 149.176 158.082 1.00 80.69  ? 295 ALA E N   1 
ATOM   13444 C CA  . ALA E 1 349 ? 118.716 148.275 159.186 1.00 80.99  ? 295 ALA E CA  1 
ATOM   13445 C C   . ALA E 1 349 ? 119.979 147.815 159.908 1.00 78.86  ? 295 ALA E C   1 
ATOM   13446 O O   . ALA E 1 349 ? 120.042 147.809 161.148 1.00 83.58  ? 295 ALA E O   1 
ATOM   13447 C CB  . ALA E 1 349 ? 117.923 147.075 158.667 1.00 76.96  ? 295 ALA E CB  1 
ATOM   13448 N N   . LEU E 1 350 ? 121.005 147.434 159.143 1.00 72.62  ? 296 LEU E N   1 
ATOM   13449 C CA  . LEU E 1 350 ? 122.251 146.983 159.758 1.00 73.83  ? 296 LEU E CA  1 
ATOM   13450 C C   . LEU E 1 350 ? 122.915 148.097 160.560 1.00 80.38  ? 296 LEU E C   1 
ATOM   13451 O O   . LEU E 1 350 ? 123.398 147.868 161.677 1.00 80.26  ? 296 LEU E O   1 
ATOM   13452 C CB  . LEU E 1 350 ? 123.201 146.452 158.687 1.00 76.51  ? 296 LEU E CB  1 
ATOM   13453 C CG  . LEU E 1 350 ? 124.604 146.079 159.166 1.00 75.44  ? 296 LEU E CG  1 
ATOM   13454 C CD1 . LEU E 1 350 ? 124.536 145.009 160.240 1.00 80.75  ? 296 LEU E CD1 1 
ATOM   13455 C CD2 . LEU E 1 350 ? 125.449 145.613 157.998 1.00 74.57  ? 296 LEU E CD2 1 
ATOM   13456 N N   . LEU E 1 351 ? 122.948 149.314 160.011 1.00 83.98  ? 297 LEU E N   1 
ATOM   13457 C CA  . LEU E 1 351 ? 123.547 150.427 160.739 1.00 83.62  ? 297 LEU E CA  1 
ATOM   13458 C C   . LEU E 1 351 ? 122.725 150.807 161.963 1.00 85.45  ? 297 LEU E C   1 
ATOM   13459 O O   . LEU E 1 351 ? 123.286 151.266 162.960 1.00 90.48  ? 297 LEU E O   1 
ATOM   13460 C CB  . LEU E 1 351 ? 123.722 151.634 159.820 1.00 82.97  ? 297 LEU E CB  1 
ATOM   13461 C CG  . LEU E 1 351 ? 124.697 151.447 158.657 1.00 87.79  ? 297 LEU E CG  1 
ATOM   13462 C CD1 . LEU E 1 351 ? 125.046 152.788 158.034 1.00 88.38  ? 297 LEU E CD1 1 
ATOM   13463 C CD2 . LEU E 1 351 ? 125.950 150.712 159.110 1.00 81.19  ? 297 LEU E CD2 1 
ATOM   13464 N N   . GLU E 1 352 ? 121.403 150.630 161.909 1.00 85.32  ? 298 GLU E N   1 
ATOM   13465 C CA  . GLU E 1 352 ? 120.581 150.852 163.092 1.00 84.01  ? 298 GLU E CA  1 
ATOM   13466 C C   . GLU E 1 352 ? 120.936 149.866 164.195 1.00 85.70  ? 298 GLU E C   1 
ATOM   13467 O O   . GLU E 1 352 ? 121.063 150.248 165.367 1.00 88.02  ? 298 GLU E O   1 
ATOM   13468 C CB  . GLU E 1 352 ? 119.101 150.745 162.724 1.00 84.33  ? 298 GLU E CB  1 
ATOM   13469 C CG  . GLU E 1 352 ? 118.153 150.692 163.910 1.00 87.28  ? 298 GLU E CG  1 
ATOM   13470 C CD  . GLU E 1 352 ? 117.757 149.276 164.279 1.00 90.09  ? 298 GLU E CD  1 
ATOM   13471 O OE1 . GLU E 1 352 ? 118.378 148.329 163.754 1.00 93.05  ? 298 GLU E OE1 1 
ATOM   13472 O OE2 . GLU E 1 352 ? 116.822 149.110 165.090 1.00 94.49  ? 298 GLU E OE2 1 
ATOM   13473 N N   . TYR E 1 353 ? 121.110 148.591 163.838 1.00 85.54  ? 299 TYR E N   1 
ATOM   13474 C CA  . TYR E 1 353 ? 121.561 147.629 164.839 1.00 86.14  ? 299 TYR E CA  1 
ATOM   13475 C C   . TYR E 1 353 ? 122.928 148.011 165.390 1.00 88.73  ? 299 TYR E C   1 
ATOM   13476 O O   . TYR E 1 353 ? 123.177 147.889 166.595 1.00 95.40  ? 299 TYR E O   1 
ATOM   13477 C CB  . TYR E 1 353 ? 121.619 146.215 164.268 1.00 88.89  ? 299 TYR E CB  1 
ATOM   13478 C CG  . TYR E 1 353 ? 122.601 145.362 165.036 1.00 94.23  ? 299 TYR E CG  1 
ATOM   13479 C CD1 . TYR E 1 353 ? 122.302 144.909 166.314 1.00 95.72  ? 299 TYR E CD1 1 
ATOM   13480 C CD2 . TYR E 1 353 ? 123.841 145.045 164.504 1.00 96.94  ? 299 TYR E CD2 1 
ATOM   13481 C CE1 . TYR E 1 353 ? 123.202 144.147 167.028 1.00 99.80  ? 299 TYR E CE1 1 
ATOM   13482 C CE2 . TYR E 1 353 ? 124.744 144.287 165.211 1.00 102.19 ? 299 TYR E CE2 1 
ATOM   13483 C CZ  . TYR E 1 353 ? 124.420 143.839 166.470 1.00 105.56 ? 299 TYR E CZ  1 
ATOM   13484 O OH  . TYR E 1 353 ? 125.325 143.082 167.171 1.00 111.51 ? 299 TYR E OH  1 
ATOM   13485 N N   . ALA E 1 354 ? 123.839 148.439 164.514 1.00 85.84  ? 300 ALA E N   1 
ATOM   13486 C CA  . ALA E 1 354 ? 125.170 148.830 164.967 1.00 84.29  ? 300 ALA E CA  1 
ATOM   13487 C C   . ALA E 1 354 ? 125.099 150.014 165.924 1.00 92.39  ? 300 ALA E C   1 
ATOM   13488 O O   . ALA E 1 354 ? 125.833 150.066 166.915 1.00 96.92  ? 300 ALA E O   1 
ATOM   13489 C CB  . ALA E 1 354 ? 126.060 149.156 163.770 1.00 85.20  ? 300 ALA E CB  1 
ATOM   13490 N N   . PHE E 1 355 ? 124.218 150.973 165.638 1.00 92.77  ? 301 PHE E N   1 
ATOM   13491 C CA  . PHE E 1 355 ? 124.019 152.116 166.524 1.00 91.08  ? 301 PHE E CA  1 
ATOM   13492 C C   . PHE E 1 355 ? 123.503 151.671 167.887 1.00 94.50  ? 301 PHE E C   1 
ATOM   13493 O O   . PHE E 1 355 ? 123.985 152.135 168.931 1.00 98.03  ? 301 PHE E O   1 
ATOM   13494 C CB  . PHE E 1 355 ? 123.046 153.092 165.862 1.00 92.42  ? 301 PHE E CB  1 
ATOM   13495 C CG  . PHE E 1 355 ? 122.869 154.387 166.597 1.00 103.34 ? 301 PHE E CG  1 
ATOM   13496 C CD1 . PHE E 1 355 ? 123.813 155.393 166.489 1.00 105.87 ? 301 PHE E CD1 1 
ATOM   13497 C CD2 . PHE E 1 355 ? 121.737 154.614 167.361 1.00 101.91 ? 301 PHE E CD2 1 
ATOM   13498 C CE1 . PHE E 1 355 ? 123.643 156.593 167.151 1.00 105.42 ? 301 PHE E CE1 1 
ATOM   13499 C CE2 . PHE E 1 355 ? 121.562 155.811 168.024 1.00 104.60 ? 301 PHE E CE2 1 
ATOM   13500 C CZ  . PHE E 1 355 ? 122.515 156.803 167.916 1.00 105.40 ? 301 PHE E CZ  1 
ATOM   13501 N N   . VAL E 1 356 ? 122.525 150.761 167.894 1.00 93.00  ? 302 VAL E N   1 
ATOM   13502 C CA  . VAL E 1 356 ? 121.978 150.257 169.153 1.00 92.34  ? 302 VAL E CA  1 
ATOM   13503 C C   . VAL E 1 356 ? 123.064 149.552 169.960 1.00 91.96  ? 302 VAL E C   1 
ATOM   13504 O O   . VAL E 1 356 ? 123.187 149.742 171.178 1.00 95.79  ? 302 VAL E O   1 
ATOM   13505 C CB  . VAL E 1 356 ? 120.783 149.327 168.880 1.00 88.73  ? 302 VAL E CB  1 
ATOM   13506 C CG1 . VAL E 1 356 ? 120.327 148.660 170.162 1.00 93.23  ? 302 VAL E CG1 1 
ATOM   13507 C CG2 . VAL E 1 356 ? 119.640 150.105 168.251 1.00 91.40  ? 302 VAL E CG2 1 
ATOM   13508 N N   . ASN E 1 357 ? 123.861 148.717 169.292 1.00 91.25  ? 303 ASN E N   1 
ATOM   13509 C CA  . ASN E 1 357 ? 124.937 148.011 169.979 1.00 93.81  ? 303 ASN E CA  1 
ATOM   13510 C C   . ASN E 1 357 ? 125.980 148.983 170.516 1.00 97.01  ? 303 ASN E C   1 
ATOM   13511 O O   . ASN E 1 357 ? 126.496 148.800 171.624 1.00 97.82  ? 303 ASN E O   1 
ATOM   13512 C CB  . ASN E 1 357 ? 125.585 146.995 169.038 1.00 96.30  ? 303 ASN E CB  1 
ATOM   13513 C CG  . ASN E 1 357 ? 126.671 146.183 169.715 1.00 95.71  ? 303 ASN E CG  1 
ATOM   13514 O OD1 . ASN E 1 357 ? 127.811 146.630 169.841 1.00 90.02  ? 303 ASN E OD1 1 
ATOM   13515 N ND2 . ASN E 1 357 ? 126.324 144.977 170.148 1.00 98.54  ? 303 ASN E ND2 1 
ATOM   13516 N N   . TYR E 1 358 ? 126.310 150.018 169.739 1.00 100.45 ? 304 TYR E N   1 
ATOM   13517 C CA  . TYR E 1 358 ? 127.305 150.987 170.181 1.00 102.41 ? 304 TYR E CA  1 
ATOM   13518 C C   . TYR E 1 358 ? 126.830 151.743 171.412 1.00 103.30 ? 304 TYR E C   1 
ATOM   13519 O O   . TYR E 1 358 ? 127.613 151.985 172.338 1.00 103.14 ? 304 TYR E O   1 
ATOM   13520 C CB  . TYR E 1 358 ? 127.641 151.960 169.053 1.00 102.29 ? 304 TYR E CB  1 
ATOM   13521 C CG  . TYR E 1 358 ? 128.619 153.036 169.467 1.00 104.06 ? 304 TYR E CG  1 
ATOM   13522 C CD1 . TYR E 1 358 ? 129.921 152.715 169.823 1.00 98.98  ? 304 TYR E CD1 1 
ATOM   13523 C CD2 . TYR E 1 358 ? 128.240 154.370 169.502 1.00 105.76 ? 304 TYR E CD2 1 
ATOM   13524 C CE1 . TYR E 1 358 ? 130.818 153.691 170.202 1.00 99.91  ? 304 TYR E CE1 1 
ATOM   13525 C CE2 . TYR E 1 358 ? 129.131 155.354 169.879 1.00 106.37 ? 304 TYR E CE2 1 
ATOM   13526 C CZ  . TYR E 1 358 ? 130.418 155.009 170.228 1.00 108.27 ? 304 TYR E CZ  1 
ATOM   13527 O OH  . TYR E 1 358 ? 131.312 155.984 170.605 1.00 116.35 ? 304 TYR E OH  1 
ATOM   13528 N N   . ILE E 1 359 ? 125.560 152.128 171.448 1.00 103.34 ? 305 ILE E N   1 
ATOM   13529 C CA  . ILE E 1 359 ? 124.975 152.715 172.652 1.00 102.71 ? 305 ILE E CA  1 
ATOM   13530 C C   . ILE E 1 359 ? 123.723 151.915 172.990 1.00 102.40 ? 305 ILE E C   1 
ATOM   13531 O O   . ILE E 1 359 ? 122.614 152.214 172.538 1.00 101.76 ? 305 ILE E O   1 
ATOM   13532 C CB  . ILE E 1 359 ? 124.672 154.209 172.500 1.00 102.41 ? 305 ILE E CB  1 
ATOM   13533 C CG1 . ILE E 1 359 ? 124.047 154.515 171.140 1.00 101.04 ? 305 ILE E CG1 1 
ATOM   13534 C CG2 . ILE E 1 359 ? 125.936 155.030 172.699 1.00 107.17 ? 305 ILE E CG2 1 
ATOM   13535 C CD1 . ILE E 1 359 ? 123.602 155.946 171.015 1.00 108.49 ? 305 ILE E CD1 1 
ATOM   13536 N N   . PHE E 1 360 ? 123.901 150.884 173.789 1.00 104.26 ? 306 PHE E N   1 
ATOM   13537 C CA  . PHE E 1 360 ? 122.849 150.184 174.514 1.00 110.33 ? 306 PHE E CA  1 
ATOM   13538 C C   . PHE E 1 360 ? 123.165 150.039 175.995 1.00 114.36 ? 306 PHE E C   1 
ATOM   13539 O O   . PHE E 1 360 ? 122.247 150.048 176.817 1.00 117.01 ? 306 PHE E O   1 
ATOM   13540 C CB  . PHE E 1 360 ? 122.608 148.793 173.902 1.00 111.23 ? 306 PHE E CB  1 
ATOM   13541 C CG  . PHE E 1 360 ? 123.493 147.720 174.471 1.00 115.32 ? 306 PHE E CG  1 
ATOM   13542 C CD1 . PHE E 1 360 ? 124.814 147.607 174.069 1.00 114.58 ? 306 PHE E CD1 1 
ATOM   13543 C CD2 . PHE E 1 360 ? 123.005 146.825 175.410 1.00 112.59 ? 306 PHE E CD2 1 
ATOM   13544 C CE1 . PHE E 1 360 ? 125.630 146.623 174.593 1.00 113.30 ? 306 PHE E CE1 1 
ATOM   13545 C CE2 . PHE E 1 360 ? 123.817 145.840 175.936 1.00 114.49 ? 306 PHE E CE2 1 
ATOM   13546 C CZ  . PHE E 1 360 ? 125.131 145.738 175.526 1.00 115.88 ? 306 PHE E CZ  1 
ATOM   13547 N N   . PHE E 1 361 ? 124.443 149.895 176.353 1.00 114.70 ? 307 PHE E N   1 
ATOM   13548 C CA  . PHE E 1 361 ? 124.808 149.656 177.746 1.00 119.45 ? 307 PHE E CA  1 
ATOM   13549 C C   . PHE E 1 361 ? 124.539 150.883 178.609 1.00 119.44 ? 307 PHE E C   1 
ATOM   13550 O O   . PHE E 1 361 ? 123.918 150.783 179.674 1.00 118.08 ? 307 PHE E O   1 
ATOM   13551 C CB  . PHE E 1 361 ? 126.277 149.242 177.830 1.00 119.71 ? 307 PHE E CB  1 
ATOM   13552 C CG  . PHE E 1 361 ? 126.781 149.073 179.232 1.00 126.28 ? 307 PHE E CG  1 
ATOM   13553 C CD1 . PHE E 1 361 ? 126.449 147.950 179.971 1.00 129.82 ? 307 PHE E CD1 1 
ATOM   13554 C CD2 . PHE E 1 361 ? 127.598 150.032 179.807 1.00 124.14 ? 307 PHE E CD2 1 
ATOM   13555 C CE1 . PHE E 1 361 ? 126.915 147.791 181.262 1.00 130.82 ? 307 PHE E CE1 1 
ATOM   13556 C CE2 . PHE E 1 361 ? 128.067 149.878 181.096 1.00 128.11 ? 307 PHE E CE2 1 
ATOM   13557 C CZ  . PHE E 1 361 ? 127.726 148.756 181.825 1.00 130.22 ? 307 PHE E CZ  1 
ATOM   13558 N N   . SER E 1 362 ? 125.002 152.053 178.167 1.00 118.20 ? 308 SER E N   1 
ATOM   13559 C CA  . SER E 1 362 ? 124.786 153.268 178.943 1.00 119.49 ? 308 SER E CA  1 
ATOM   13560 C C   . SER E 1 362 ? 123.350 153.763 178.827 1.00 122.01 ? 308 SER E C   1 
ATOM   13561 O O   . SER E 1 362 ? 122.851 154.430 179.741 1.00 126.51 ? 308 SER E O   1 
ATOM   13562 C CB  . SER E 1 362 ? 125.763 154.355 178.497 1.00 116.25 ? 308 SER E CB  1 
ATOM   13563 O OG  . SER E 1 362 ? 125.674 154.577 177.101 1.00 112.52 ? 308 SER E OG  1 
ATOM   13564 N N   . GLN E 1 363 ? 122.676 153.457 177.721 1.00 119.01 ? 309 GLN E N   1 
ATOM   13565 C CA  . GLN E 1 363 ? 121.312 153.917 177.461 1.00 114.46 ? 309 GLN E CA  1 
ATOM   13566 C C   . GLN E 1 363 ? 120.470 152.738 176.991 1.00 115.12 ? 309 GLN E C   1 
ATOM   13567 O O   . GLN E 1 363 ? 120.202 152.590 175.791 1.00 114.52 ? 309 GLN E O   1 
ATOM   13568 C CB  . GLN E 1 363 ? 121.307 155.051 176.436 1.00 117.82 ? 309 GLN E CB  1 
ATOM   13569 C CG  . GLN E 1 363 ? 121.981 156.325 176.923 1.00 121.89 ? 309 GLN E CG  1 
ATOM   13570 C CD  . GLN E 1 363 ? 122.407 157.234 175.788 1.00 119.64 ? 309 GLN E CD  1 
ATOM   13571 O OE1 . GLN E 1 363 ? 122.766 156.769 174.707 1.00 114.52 ? 309 GLN E OE1 1 
ATOM   13572 N NE2 . GLN E 1 363 ? 122.368 158.540 176.029 1.00 117.09 ? 309 GLN E NE2 1 
ATOM   13573 N N   . PRO E 1 364 ? 120.037 151.872 177.913 1.00 117.31 ? 310 PRO E N   1 
ATOM   13574 C CA  . PRO E 1 364 ? 119.234 150.712 177.487 1.00 118.86 ? 310 PRO E CA  1 
ATOM   13575 C C   . PRO E 1 364 ? 117.819 151.075 177.077 1.00 115.28 ? 310 PRO E C   1 
ATOM   13576 O O   . PRO E 1 364 ? 117.297 150.509 176.107 1.00 114.55 ? 310 PRO E O   1 
ATOM   13577 C CB  . PRO E 1 364 ? 119.258 149.804 178.724 1.00 115.36 ? 310 PRO E CB  1 
ATOM   13578 C CG  . PRO E 1 364 ? 119.436 150.745 179.868 1.00 113.35 ? 310 PRO E CG  1 
ATOM   13579 C CD  . PRO E 1 364 ? 120.307 151.863 179.361 1.00 113.01 ? 310 PRO E CD  1 
ATOM   13580 N N   . ALA E 1 365 ? 117.176 152.000 177.794 1.00 112.36 ? 311 ALA E N   1 
ATOM   13581 C CA  . ALA E 1 365 ? 115.835 152.430 177.413 1.00 110.06 ? 311 ALA E CA  1 
ATOM   13582 C C   . ALA E 1 365 ? 115.847 153.098 176.045 1.00 116.01 ? 311 ALA E C   1 
ATOM   13583 O O   . ALA E 1 365 ? 114.939 152.885 175.232 1.00 119.22 ? 311 ALA E O   1 
ATOM   13584 C CB  . ALA E 1 365 ? 115.265 153.375 178.470 1.00 99.11  ? 311 ALA E CB  1 
ATOM   13585 N N   . ARG E 1 366 ? 116.873 153.908 175.777 1.00 115.17 ? 312 ARG E N   1 
ATOM   13586 C CA  . ARG E 1 366 ? 117.024 154.516 174.460 1.00 115.55 ? 312 ARG E CA  1 
ATOM   13587 C C   . ARG E 1 366 ? 117.166 153.453 173.380 1.00 113.02 ? 312 ARG E C   1 
ATOM   13588 O O   . ARG E 1 366 ? 116.551 153.555 172.312 1.00 110.51 ? 312 ARG E O   1 
ATOM   13589 C CB  . ARG E 1 366 ? 118.235 155.448 174.465 1.00 116.97 ? 312 ARG E CB  1 
ATOM   13590 C CG  . ARG E 1 366 ? 118.568 156.090 173.131 1.00 115.57 ? 312 ARG E CG  1 
ATOM   13591 C CD  . ARG E 1 366 ? 119.877 156.857 173.238 1.00 120.09 ? 312 ARG E CD  1 
ATOM   13592 N NE  . ARG E 1 366 ? 120.149 157.678 172.065 1.00 121.48 ? 312 ARG E NE  1 
ATOM   13593 C CZ  . ARG E 1 366 ? 121.222 158.445 171.925 1.00 122.88 ? 312 ARG E CZ  1 
ATOM   13594 N NH1 . ARG E 1 366 ? 122.153 158.507 172.862 1.00 123.72 ? 312 ARG E NH1 1 
ATOM   13595 N NH2 . ARG E 1 366 ? 121.363 159.168 170.818 1.00 118.09 ? 312 ARG E NH2 1 
ATOM   13596 N N   . ALA E 1 367 ? 117.965 152.416 173.647 1.00 111.55 ? 313 ALA E N   1 
ATOM   13597 C CA  . ALA E 1 367 ? 118.145 151.344 172.675 1.00 108.50 ? 313 ALA E CA  1 
ATOM   13598 C C   . ALA E 1 367 ? 116.838 150.609 172.406 1.00 110.09 ? 313 ALA E C   1 
ATOM   13599 O O   . ALA E 1 367 ? 116.502 150.331 171.249 1.00 111.06 ? 313 ALA E O   1 
ATOM   13600 C CB  . ALA E 1 367 ? 119.216 150.371 173.168 1.00 105.12 ? 313 ALA E CB  1 
ATOM   13601 N N   . ALA E 1 368 ? 116.084 150.287 173.461 1.00 110.01 ? 314 ALA E N   1 
ATOM   13602 C CA  . ALA E 1 368 ? 114.821 149.578 173.275 1.00 109.61 ? 314 ALA E CA  1 
ATOM   13603 C C   . ALA E 1 368 ? 113.808 150.431 172.520 1.00 111.09 ? 314 ALA E C   1 
ATOM   13604 O O   . ALA E 1 368 ? 113.098 149.930 171.636 1.00 110.25 ? 314 ALA E O   1 
ATOM   13605 C CB  . ALA E 1 368 ? 114.258 149.144 174.627 1.00 114.88 ? 314 ALA E CB  1 
ATOM   13606 N N   . ALA E 1 369 ? 113.725 151.722 172.854 1.00 111.67 ? 422 ALA E N   1 
ATOM   13607 C CA  . ALA E 1 369 ? 112.807 152.608 172.147 1.00 112.99 ? 422 ALA E CA  1 
ATOM   13608 C C   . ALA E 1 369 ? 113.187 152.736 170.678 1.00 114.88 ? 422 ALA E C   1 
ATOM   13609 O O   . ALA E 1 369 ? 112.316 152.718 169.800 1.00 113.27 ? 422 ALA E O   1 
ATOM   13610 C CB  . ALA E 1 369 ? 112.779 153.980 172.820 1.00 111.88 ? 422 ALA E CB  1 
ATOM   13611 N N   . ILE E 1 370 ? 114.486 152.866 170.391 1.00 115.17 ? 423 ILE E N   1 
ATOM   13612 C CA  . ILE E 1 370 ? 114.938 152.953 169.006 1.00 108.83 ? 423 ILE E CA  1 
ATOM   13613 C C   . ILE E 1 370 ? 114.614 151.668 168.259 1.00 106.24 ? 423 ILE E C   1 
ATOM   13614 O O   . ILE E 1 370 ? 114.198 151.699 167.095 1.00 107.26 ? 423 ILE E O   1 
ATOM   13615 C CB  . ILE E 1 370 ? 116.442 153.284 168.954 1.00 106.55 ? 423 ILE E CB  1 
ATOM   13616 C CG1 . ILE E 1 370 ? 116.656 154.793 169.075 1.00 107.21 ? 423 ILE E CG1 1 
ATOM   13617 C CG2 . ILE E 1 370 ? 117.077 152.751 167.680 1.00 101.44 ? 423 ILE E CG2 1 
ATOM   13618 C CD1 . ILE E 1 370 ? 118.085 155.228 168.843 1.00 106.74 ? 423 ILE E CD1 1 
ATOM   13619 N N   . ASP E 1 371 ? 114.795 150.518 168.913 1.00 104.04 ? 424 ASP E N   1 
ATOM   13620 C CA  . ASP E 1 371 ? 114.471 149.251 168.267 1.00 101.59 ? 424 ASP E CA  1 
ATOM   13621 C C   . ASP E 1 371 ? 112.987 149.167 167.932 1.00 104.39 ? 424 ASP E C   1 
ATOM   13622 O O   . ASP E 1 371 ? 112.618 148.775 166.819 1.00 105.80 ? 424 ASP E O   1 
ATOM   13623 C CB  . ASP E 1 371 ? 114.890 148.085 169.162 1.00 101.36 ? 424 ASP E CB  1 
ATOM   13624 C CG  . ASP E 1 371 ? 115.043 146.788 168.394 1.00 101.79 ? 424 ASP E CG  1 
ATOM   13625 O OD1 . ASP E 1 371 ? 114.807 146.792 167.169 1.00 103.17 ? 424 ASP E OD1 1 
ATOM   13626 O OD2 . ASP E 1 371 ? 115.406 145.767 169.012 1.00 106.63 ? 424 ASP E OD2 1 
ATOM   13627 N N   . ARG E 1 372 ? 112.120 149.551 168.875 1.00 104.18 ? 425 ARG E N   1 
ATOM   13628 C CA  . ARG E 1 372 ? 110.683 149.525 168.605 1.00 105.83 ? 425 ARG E CA  1 
ATOM   13629 C C   . ARG E 1 372 ? 110.310 150.485 167.481 1.00 108.28 ? 425 ARG E C   1 
ATOM   13630 O O   . ARG E 1 372 ? 109.501 150.152 166.602 1.00 106.70 ? 425 ARG E O   1 
ATOM   13631 C CB  . ARG E 1 372 ? 109.894 149.876 169.865 1.00 112.43 ? 425 ARG E CB  1 
ATOM   13632 C CG  . ARG E 1 372 ? 110.090 148.935 171.033 1.00 116.99 ? 425 ARG E CG  1 
ATOM   13633 C CD  . ARG E 1 372 ? 109.016 149.178 172.080 1.00 121.29 ? 425 ARG E CD  1 
ATOM   13634 N NE  . ARG E 1 372 ? 108.590 150.573 172.098 1.00 122.74 ? 425 ARG E NE  1 
ATOM   13635 C CZ  . ARG E 1 372 ? 109.125 151.511 172.867 1.00 118.77 ? 425 ARG E CZ  1 
ATOM   13636 N NH1 . ARG E 1 372 ? 110.108 151.237 173.708 1.00 117.77 ? 425 ARG E NH1 1 
ATOM   13637 N NH2 . ARG E 1 372 ? 108.660 152.755 172.791 1.00 114.91 ? 425 ARG E NH2 1 
ATOM   13638 N N   . TRP E 1 373 ? 110.882 151.689 167.498 1.00 110.18 ? 426 TRP E N   1 
ATOM   13639 C CA  . TRP E 1 373 ? 110.544 152.665 166.470 1.00 108.63 ? 426 TRP E CA  1 
ATOM   13640 C C   . TRP E 1 373 ? 111.032 152.215 165.102 1.00 106.00 ? 426 TRP E C   1 
ATOM   13641 O O   . TRP E 1 373 ? 110.358 152.447 164.097 1.00 106.17 ? 426 TRP E O   1 
ATOM   13642 C CB  . TRP E 1 373 ? 111.102 154.038 166.836 1.00 113.31 ? 426 TRP E CB  1 
ATOM   13643 C CG  . TRP E 1 373 ? 110.249 154.749 167.843 1.00 119.36 ? 426 TRP E CG  1 
ATOM   13644 C CD1 . TRP E 1 373 ? 110.609 155.129 169.102 1.00 121.15 ? 426 TRP E CD1 1 
ATOM   13645 C CD2 . TRP E 1 373 ? 108.880 155.143 167.681 1.00 123.84 ? 426 TRP E CD2 1 
ATOM   13646 N NE1 . TRP E 1 373 ? 109.554 155.746 169.731 1.00 124.70 ? 426 TRP E NE1 1 
ATOM   13647 C CE2 . TRP E 1 373 ? 108.481 155.766 168.879 1.00 129.01 ? 426 TRP E CE2 1 
ATOM   13648 C CE3 . TRP E 1 373 ? 107.956 155.034 166.637 1.00 119.29 ? 426 TRP E CE3 1 
ATOM   13649 C CZ2 . TRP E 1 373 ? 107.198 156.278 169.063 1.00 133.02 ? 426 TRP E CZ2 1 
ATOM   13650 C CZ3 . TRP E 1 373 ? 106.684 155.543 166.821 1.00 126.07 ? 426 TRP E CZ3 1 
ATOM   13651 C CH2 . TRP E 1 373 ? 106.316 156.157 168.024 1.00 134.09 ? 426 TRP E CH2 1 
ATOM   13652 N N   . SER E 1 374 ? 112.194 151.560 165.037 1.00 105.62 ? 427 SER E N   1 
ATOM   13653 C CA  . SER E 1 374 ? 112.624 150.966 163.775 1.00 97.86  ? 427 SER E CA  1 
ATOM   13654 C C   . SER E 1 374 ? 111.662 149.872 163.332 1.00 92.46  ? 427 SER E C   1 
ATOM   13655 O O   . SER E 1 374 ? 111.308 149.790 162.148 1.00 90.51  ? 427 SER E O   1 
ATOM   13656 C CB  . SER E 1 374 ? 114.043 150.416 163.904 1.00 92.36  ? 427 SER E CB  1 
ATOM   13657 O OG  . SER E 1 374 ? 114.984 151.469 164.018 1.00 90.90  ? 427 SER E OG  1 
ATOM   13658 N N   . ARG E 1 375 ? 111.220 149.030 164.274 1.00 93.04  ? 428 ARG E N   1 
ATOM   13659 C CA  . ARG E 1 375 ? 110.229 148.002 163.968 1.00 95.72  ? 428 ARG E CA  1 
ATOM   13660 C C   . ARG E 1 375 ? 109.006 148.608 163.296 1.00 94.49  ? 428 ARG E C   1 
ATOM   13661 O O   . ARG E 1 375 ? 108.459 148.046 162.342 1.00 91.76  ? 428 ARG E O   1 
ATOM   13662 C CB  . ARG E 1 375 ? 109.798 147.274 165.244 1.00 101.72 ? 428 ARG E CB  1 
ATOM   13663 C CG  . ARG E 1 375 ? 110.843 146.405 165.909 1.00 100.06 ? 428 ARG E CG  1 
ATOM   13664 C CD  . ARG E 1 375 ? 110.293 145.821 167.202 1.00 100.39 ? 428 ARG E CD  1 
ATOM   13665 N NE  . ARG E 1 375 ? 111.294 145.074 167.953 1.00 101.39 ? 428 ARG E NE  1 
ATOM   13666 C CZ  . ARG E 1 375 ? 111.069 144.494 169.124 1.00 101.42 ? 428 ARG E CZ  1 
ATOM   13667 N NH1 . ARG E 1 375 ? 109.882 144.551 169.706 1.00 106.77 ? 428 ARG E NH1 1 
ATOM   13668 N NH2 . ARG E 1 375 ? 112.058 143.840 169.726 1.00 93.76  ? 428 ARG E NH2 1 
ATOM   13669 N N   . ILE E 1 376 ? 108.558 149.760 163.796 1.00 97.67  ? 429 ILE E N   1 
ATOM   13670 C CA  . ILE E 1 376 ? 107.318 150.334 163.280 1.00 97.68  ? 429 ILE E CA  1 
ATOM   13671 C C   . ILE E 1 376 ? 107.577 151.204 162.048 1.00 97.22  ? 429 ILE E C   1 
ATOM   13672 O O   . ILE E 1 376 ? 106.663 151.450 161.251 1.00 97.12  ? 429 ILE E O   1 
ATOM   13673 C CB  . ILE E 1 376 ? 106.596 151.115 164.395 1.00 99.46  ? 429 ILE E CB  1 
ATOM   13674 C CG1 . ILE E 1 376 ? 106.475 150.249 165.650 1.00 100.10 ? 429 ILE E CG1 1 
ATOM   13675 C CG2 . ILE E 1 376 ? 105.210 151.542 163.946 1.00 98.70  ? 429 ILE E CG2 1 
ATOM   13676 C CD1 . ILE E 1 376 ? 105.684 150.894 166.770 1.00 113.80 ? 429 ILE E CD1 1 
ATOM   13677 N N   . VAL E 1 377 ? 108.814 151.659 161.851 1.00 93.86  ? 430 VAL E N   1 
ATOM   13678 C CA  . VAL E 1 377 ? 109.095 152.610 160.781 1.00 89.32  ? 430 VAL E CA  1 
ATOM   13679 C C   . VAL E 1 377 ? 109.495 151.895 159.496 1.00 92.31  ? 430 VAL E C   1 
ATOM   13680 O O   . VAL E 1 377 ? 109.006 152.232 158.412 1.00 94.24  ? 430 VAL E O   1 
ATOM   13681 C CB  . VAL E 1 377 ? 110.176 153.611 161.232 1.00 86.33  ? 430 VAL E CB  1 
ATOM   13682 C CG1 . VAL E 1 377 ? 110.898 154.202 160.031 1.00 86.04  ? 430 VAL E CG1 1 
ATOM   13683 C CG2 . VAL E 1 377 ? 109.551 154.719 162.064 1.00 88.39  ? 430 VAL E CG2 1 
ATOM   13684 N N   . PHE E 1 378 ? 110.393 150.911 159.591 1.00 89.59  ? 431 PHE E N   1 
ATOM   13685 C CA  . PHE E 1 378 ? 110.969 150.320 158.383 1.00 83.92  ? 431 PHE E CA  1 
ATOM   13686 C C   . PHE E 1 378 ? 109.925 149.744 157.431 1.00 87.73  ? 431 PHE E C   1 
ATOM   13687 O O   . PHE E 1 378 ? 109.998 150.043 156.225 1.00 92.94  ? 431 PHE E O   1 
ATOM   13688 C CB  . PHE E 1 378 ? 112.019 149.274 158.771 1.00 83.06  ? 431 PHE E CB  1 
ATOM   13689 C CG  . PHE E 1 378 ? 113.428 149.795 158.750 1.00 86.47  ? 431 PHE E CG  1 
ATOM   13690 C CD1 . PHE E 1 378 ? 113.855 150.718 159.689 1.00 88.60  ? 431 PHE E CD1 1 
ATOM   13691 C CD2 . PHE E 1 378 ? 114.327 149.355 157.794 1.00 83.92  ? 431 PHE E CD2 1 
ATOM   13692 C CE1 . PHE E 1 378 ? 115.150 151.197 159.670 1.00 84.45  ? 431 PHE E CE1 1 
ATOM   13693 C CE2 . PHE E 1 378 ? 115.623 149.829 157.772 1.00 80.23  ? 431 PHE E CE2 1 
ATOM   13694 C CZ  . PHE E 1 378 ? 116.035 150.752 158.710 1.00 78.51  ? 431 PHE E CZ  1 
ATOM   13695 N N   . PRO E 1 379 ? 108.956 148.927 157.869 1.00 88.26  ? 432 PRO E N   1 
ATOM   13696 C CA  . PRO E 1 379 ? 107.928 148.472 156.916 1.00 89.86  ? 432 PRO E CA  1 
ATOM   13697 C C   . PRO E 1 379 ? 107.148 149.610 156.283 1.00 96.03  ? 432 PRO E C   1 
ATOM   13698 O O   . PRO E 1 379 ? 106.851 149.558 155.084 1.00 100.22 ? 432 PRO E O   1 
ATOM   13699 C CB  . PRO E 1 379 ? 107.029 147.573 157.775 1.00 84.34  ? 432 PRO E CB  1 
ATOM   13700 C CG  . PRO E 1 379 ? 107.900 147.122 158.884 1.00 85.05  ? 432 PRO E CG  1 
ATOM   13701 C CD  . PRO E 1 379 ? 108.784 148.290 159.187 1.00 88.86  ? 432 PRO E CD  1 
ATOM   13702 N N   . PHE E 1 380 ? 106.828 150.652 157.053 1.00 93.80  ? 433 PHE E N   1 
ATOM   13703 C CA  . PHE E 1 380 ? 106.066 151.776 156.516 1.00 94.78  ? 433 PHE E CA  1 
ATOM   13704 C C   . PHE E 1 380 ? 106.851 152.503 155.430 1.00 98.07  ? 433 PHE E C   1 
ATOM   13705 O O   . PHE E 1 380 ? 106.331 152.770 154.338 1.00 98.84  ? 433 PHE E O   1 
ATOM   13706 C CB  . PHE E 1 380 ? 105.694 152.728 157.656 1.00 93.99  ? 433 PHE E CB  1 
ATOM   13707 C CG  . PHE E 1 380 ? 105.094 154.027 157.202 1.00 98.51  ? 433 PHE E CG  1 
ATOM   13708 C CD1 . PHE E 1 380 ? 103.751 154.110 156.878 1.00 100.46 ? 433 PHE E CD1 1 
ATOM   13709 C CD2 . PHE E 1 380 ? 105.869 155.173 157.121 1.00 100.32 ? 433 PHE E CD2 1 
ATOM   13710 C CE1 . PHE E 1 380 ? 103.195 155.307 156.467 1.00 104.74 ? 433 PHE E CE1 1 
ATOM   13711 C CE2 . PHE E 1 380 ? 105.319 156.372 156.711 1.00 103.29 ? 433 PHE E CE2 1 
ATOM   13712 C CZ  . PHE E 1 380 ? 103.980 156.439 156.385 1.00 105.92 ? 433 PHE E CZ  1 
ATOM   13713 N N   . THR E 1 381 ? 108.117 152.820 155.712 1.00 95.84  ? 434 THR E N   1 
ATOM   13714 C CA  . THR E 1 381 ? 108.942 153.522 154.736 1.00 98.33  ? 434 THR E CA  1 
ATOM   13715 C C   . THR E 1 381 ? 109.169 152.673 153.492 1.00 96.21  ? 434 THR E C   1 
ATOM   13716 O O   . THR E 1 381 ? 109.130 153.185 152.368 1.00 93.91  ? 434 THR E O   1 
ATOM   13717 C CB  . THR E 1 381 ? 110.277 153.917 155.365 1.00 93.70  ? 434 THR E CB  1 
ATOM   13718 O OG1 . THR E 1 381 ? 110.036 154.668 156.561 1.00 90.12  ? 434 THR E OG1 1 
ATOM   13719 C CG2 . THR E 1 381 ? 111.087 154.766 154.402 1.00 97.05  ? 434 THR E CG2 1 
ATOM   13720 N N   . PHE E 1 382 ? 109.408 151.372 153.671 1.00 94.49  ? 435 PHE E N   1 
ATOM   13721 C CA  . PHE E 1 382 ? 109.631 150.506 152.518 1.00 88.88  ? 435 PHE E CA  1 
ATOM   13722 C C   . PHE E 1 382 ? 108.373 150.372 151.669 1.00 93.42  ? 435 PHE E C   1 
ATOM   13723 O O   . PHE E 1 382 ? 108.453 150.352 150.436 1.00 96.48  ? 435 PHE E O   1 
ATOM   13724 C CB  . PHE E 1 382 ? 110.120 149.139 152.984 1.00 85.41  ? 435 PHE E CB  1 
ATOM   13725 C CG  . PHE E 1 382 ? 110.339 148.154 151.873 1.00 86.45  ? 435 PHE E CG  1 
ATOM   13726 C CD1 . PHE E 1 382 ? 111.465 148.230 151.073 1.00 89.38  ? 435 PHE E CD1 1 
ATOM   13727 C CD2 . PHE E 1 382 ? 109.428 147.136 151.642 1.00 88.71  ? 435 PHE E CD2 1 
ATOM   13728 C CE1 . PHE E 1 382 ? 111.673 147.319 150.056 1.00 93.25  ? 435 PHE E CE1 1 
ATOM   13729 C CE2 . PHE E 1 382 ? 109.631 146.221 150.629 1.00 89.86  ? 435 PHE E CE2 1 
ATOM   13730 C CZ  . PHE E 1 382 ? 110.754 146.312 149.835 1.00 90.96  ? 435 PHE E CZ  1 
ATOM   13731 N N   . SER E 1 383 ? 107.203 150.272 152.305 1.00 92.80  ? 436 SER E N   1 
ATOM   13732 C CA  . SER E 1 383 ? 105.958 150.204 151.549 1.00 95.72  ? 436 SER E CA  1 
ATOM   13733 C C   . SER E 1 383 ? 105.710 151.495 150.782 1.00 98.24  ? 436 SER E C   1 
ATOM   13734 O O   . SER E 1 383 ? 105.270 151.465 149.626 1.00 99.43  ? 436 SER E O   1 
ATOM   13735 C CB  . SER E 1 383 ? 104.790 149.903 152.487 1.00 99.78  ? 436 SER E CB  1 
ATOM   13736 O OG  . SER E 1 383 ? 104.973 148.660 153.142 1.00 109.58 ? 436 SER E OG  1 
ATOM   13737 N N   . LEU E 1 384 ? 105.984 152.642 151.410 1.00 94.29  ? 437 LEU E N   1 
ATOM   13738 C CA  . LEU E 1 384 ? 105.856 153.914 150.705 1.00 97.35  ? 437 LEU E CA  1 
ATOM   13739 C C   . LEU E 1 384 ? 106.810 153.983 149.519 1.00 98.02  ? 437 LEU E C   1 
ATOM   13740 O O   . LEU E 1 384 ? 106.432 154.439 148.431 1.00 93.68  ? 437 LEU E O   1 
ATOM   13741 C CB  . LEU E 1 384 ? 106.109 155.072 151.670 1.00 90.52  ? 437 LEU E CB  1 
ATOM   13742 C CG  . LEU E 1 384 ? 106.164 156.476 151.066 1.00 94.96  ? 437 LEU E CG  1 
ATOM   13743 C CD1 . LEU E 1 384 ? 104.847 156.828 150.390 1.00 97.38  ? 437 LEU E CD1 1 
ATOM   13744 C CD2 . LEU E 1 384 ? 106.520 157.502 152.132 1.00 89.38  ? 437 LEU E CD2 1 
ATOM   13745 N N   . PHE E 1 385 ? 108.052 153.532 149.711 1.00 97.13  ? 438 PHE E N   1 
ATOM   13746 C CA  . PHE E 1 385 ? 109.022 153.516 148.622 1.00 91.27  ? 438 PHE E CA  1 
ATOM   13747 C C   . PHE E 1 385 ? 108.548 152.633 147.477 1.00 87.94  ? 438 PHE E C   1 
ATOM   13748 O O   . PHE E 1 385 ? 108.641 153.019 146.308 1.00 87.43  ? 438 PHE E O   1 
ATOM   13749 C CB  . PHE E 1 385 ? 110.379 153.038 149.140 1.00 92.69  ? 438 PHE E CB  1 
ATOM   13750 C CG  . PHE E 1 385 ? 111.378 152.749 148.055 1.00 91.80  ? 438 PHE E CG  1 
ATOM   13751 C CD1 . PHE E 1 385 ? 112.137 153.768 147.507 1.00 90.94  ? 438 PHE E CD1 1 
ATOM   13752 C CD2 . PHE E 1 385 ? 111.567 151.456 147.591 1.00 86.30  ? 438 PHE E CD2 1 
ATOM   13753 C CE1 . PHE E 1 385 ? 113.060 153.506 146.513 1.00 83.98  ? 438 PHE E CE1 1 
ATOM   13754 C CE2 . PHE E 1 385 ? 112.486 151.189 146.597 1.00 79.05  ? 438 PHE E CE2 1 
ATOM   13755 C CZ  . PHE E 1 385 ? 113.234 152.215 146.058 1.00 78.33  ? 438 PHE E CZ  1 
ATOM   13756 N N   . ASN E 1 386 ? 108.036 151.443 147.794 1.00 88.70  ? 439 ASN E N   1 
ATOM   13757 C CA  . ASN E 1 386 ? 107.550 150.547 146.750 1.00 89.52  ? 439 ASN E CA  1 
ATOM   13758 C C   . ASN E 1 386 ? 106.370 151.152 146.006 1.00 91.53  ? 439 ASN E C   1 
ATOM   13759 O O   . ASN E 1 386 ? 106.295 151.069 144.775 1.00 93.29  ? 439 ASN E O   1 
ATOM   13760 C CB  . ASN E 1 386 ? 107.166 149.197 147.352 1.00 92.06  ? 439 ASN E CB  1 
ATOM   13761 C CG  . ASN E 1 386 ? 108.369 148.388 147.769 1.00 96.23  ? 439 ASN E CG  1 
ATOM   13762 O OD1 . ASN E 1 386 ? 108.763 147.443 147.088 1.00 101.38 ? 439 ASN E OD1 1 
ATOM   13763 N ND2 . ASN E 1 386 ? 108.972 148.764 148.888 1.00 95.36  ? 439 ASN E ND2 1 
ATOM   13764 N N   . LEU E 1 387 ? 105.434 151.761 146.734 1.00 88.52  ? 440 LEU E N   1 
ATOM   13765 C CA  . LEU E 1 387 ? 104.271 152.352 146.082 1.00 91.15  ? 440 LEU E CA  1 
ATOM   13766 C C   . LEU E 1 387 ? 104.684 153.489 145.156 1.00 92.66  ? 440 LEU E C   1 
ATOM   13767 O O   . LEU E 1 387 ? 104.236 153.561 144.006 1.00 93.27  ? 440 LEU E O   1 
ATOM   13768 C CB  . LEU E 1 387 ? 103.272 152.838 147.131 1.00 94.09  ? 440 LEU E CB  1 
ATOM   13769 C CG  . LEU E 1 387 ? 101.864 153.146 146.619 1.00 98.49  ? 440 LEU E CG  1 
ATOM   13770 C CD1 . LEU E 1 387 ? 101.297 151.942 145.884 1.00 89.16  ? 440 LEU E CD1 1 
ATOM   13771 C CD2 . LEU E 1 387 ? 100.959 153.546 147.771 1.00 106.17 ? 440 LEU E CD2 1 
ATOM   13772 N N   . VAL E 1 388 ? 105.562 154.375 145.632 1.00 89.90  ? 441 VAL E N   1 
ATOM   13773 C CA  . VAL E 1 388 ? 105.976 155.503 144.803 1.00 92.52  ? 441 VAL E CA  1 
ATOM   13774 C C   . VAL E 1 388 ? 106.802 155.022 143.612 1.00 93.81  ? 441 VAL E C   1 
ATOM   13775 O O   . VAL E 1 388 ? 106.717 155.587 142.515 1.00 91.30  ? 441 VAL E O   1 
ATOM   13776 C CB  . VAL E 1 388 ? 106.720 156.556 145.650 1.00 90.45  ? 441 VAL E CB  1 
ATOM   13777 C CG1 . VAL E 1 388 ? 108.157 156.144 145.927 1.00 91.95  ? 441 VAL E CG1 1 
ATOM   13778 C CG2 . VAL E 1 388 ? 106.666 157.917 144.973 1.00 91.22  ? 441 VAL E CG2 1 
ATOM   13779 N N   . TYR E 1 389 ? 107.596 153.962 143.796 1.00 94.62  ? 442 TYR E N   1 
ATOM   13780 C CA  . TYR E 1 389 ? 108.379 153.422 142.690 1.00 86.12  ? 442 TYR E CA  1 
ATOM   13781 C C   . TYR E 1 389 ? 107.474 152.826 141.621 1.00 83.74  ? 442 TYR E C   1 
ATOM   13782 O O   . TYR E 1 389 ? 107.606 153.146 140.434 1.00 90.03  ? 442 TYR E O   1 
ATOM   13783 C CB  . TYR E 1 389 ? 109.367 152.377 143.212 1.00 84.99  ? 442 TYR E CB  1 
ATOM   13784 C CG  . TYR E 1 389 ? 109.992 151.516 142.136 1.00 78.22  ? 442 TYR E CG  1 
ATOM   13785 C CD1 . TYR E 1 389 ? 111.123 151.938 141.451 1.00 75.39  ? 442 TYR E CD1 1 
ATOM   13786 C CD2 . TYR E 1 389 ? 109.458 150.276 141.814 1.00 77.71  ? 442 TYR E CD2 1 
ATOM   13787 C CE1 . TYR E 1 389 ? 111.696 151.152 140.471 1.00 76.51  ? 442 TYR E CE1 1 
ATOM   13788 C CE2 . TYR E 1 389 ? 110.024 149.487 140.836 1.00 76.17  ? 442 TYR E CE2 1 
ATOM   13789 C CZ  . TYR E 1 389 ? 111.143 149.929 140.168 1.00 75.78  ? 442 TYR E CZ  1 
ATOM   13790 O OH  . TYR E 1 389 ? 111.707 149.140 139.194 1.00 77.67  ? 442 TYR E OH  1 
ATOM   13791 N N   . TRP E 1 390 ? 106.543 151.960 142.022 1.00 81.67  ? 443 TRP E N   1 
ATOM   13792 C CA  . TRP E 1 390 ? 105.650 151.343 141.051 1.00 83.68  ? 443 TRP E CA  1 
ATOM   13793 C C   . TRP E 1 390 ? 104.678 152.344 140.439 1.00 90.60  ? 443 TRP E C   1 
ATOM   13794 O O   . TRP E 1 390 ? 104.136 152.077 139.363 1.00 90.64  ? 443 TRP E O   1 
ATOM   13795 C CB  . TRP E 1 390 ? 104.888 150.182 141.694 1.00 81.09  ? 443 TRP E CB  1 
ATOM   13796 C CG  . TRP E 1 390 ? 105.759 148.994 141.994 1.00 91.15  ? 443 TRP E CG  1 
ATOM   13797 C CD1 . TRP E 1 390 ? 106.282 148.644 143.204 1.00 97.68  ? 443 TRP E CD1 1 
ATOM   13798 C CD2 . TRP E 1 390 ? 106.213 148.004 141.063 1.00 86.39  ? 443 TRP E CD2 1 
ATOM   13799 N NE1 . TRP E 1 390 ? 107.030 147.498 143.087 1.00 97.53  ? 443 TRP E NE1 1 
ATOM   13800 C CE2 . TRP E 1 390 ? 107.003 147.085 141.781 1.00 89.00  ? 443 TRP E CE2 1 
ATOM   13801 C CE3 . TRP E 1 390 ? 106.026 147.805 139.693 1.00 82.89  ? 443 TRP E CE3 1 
ATOM   13802 C CZ2 . TRP E 1 390 ? 107.605 145.985 141.176 1.00 81.72  ? 443 TRP E CZ2 1 
ATOM   13803 C CZ3 . TRP E 1 390 ? 106.624 146.713 139.094 1.00 83.07  ? 443 TRP E CZ3 1 
ATOM   13804 C CH2 . TRP E 1 390 ? 107.404 145.817 139.835 1.00 82.16  ? 443 TRP E CH2 1 
ATOM   13805 N N   . LEU E 1 391 ? 104.439 153.483 141.095 1.00 94.06  ? 444 LEU E N   1 
ATOM   13806 C CA  . LEU E 1 391 ? 103.681 154.550 140.450 1.00 96.96  ? 444 LEU E CA  1 
ATOM   13807 C C   . LEU E 1 391 ? 104.539 155.325 139.455 1.00 95.12  ? 444 LEU E C   1 
ATOM   13808 O O   . LEU E 1 391 ? 104.032 155.796 138.431 1.00 88.46  ? 444 LEU E O   1 
ATOM   13809 C CB  . LEU E 1 391 ? 103.097 155.497 141.499 1.00 92.81  ? 444 LEU E CB  1 
ATOM   13810 C CG  . LEU E 1 391 ? 101.903 154.968 142.295 1.00 91.20  ? 444 LEU E CG  1 
ATOM   13811 C CD1 . LEU E 1 391 ? 101.376 156.036 143.241 1.00 88.19  ? 444 LEU E CD1 1 
ATOM   13812 C CD2 . LEU E 1 391 ? 100.806 154.483 141.361 1.00 86.70  ? 444 LEU E CD2 1 
ATOM   13813 N N   . TYR E 1 392 ? 105.833 155.478 139.748 1.00 94.57  ? 445 TYR E N   1 
ATOM   13814 C CA  . TYR E 1 392 ? 106.713 156.230 138.859 1.00 91.52  ? 445 TYR E CA  1 
ATOM   13815 C C   . TYR E 1 392 ? 106.835 155.558 137.497 1.00 91.01  ? 445 TYR E C   1 
ATOM   13816 O O   . TYR E 1 392 ? 106.796 156.230 136.460 1.00 87.69  ? 445 TYR E O   1 
ATOM   13817 C CB  . TYR E 1 392 ? 108.091 156.389 139.502 1.00 93.43  ? 445 TYR E CB  1 
ATOM   13818 C CG  . TYR E 1 392 ? 109.006 157.356 138.783 1.00 98.90  ? 445 TYR E CG  1 
ATOM   13819 C CD1 . TYR E 1 392 ? 109.791 156.939 137.715 1.00 95.90  ? 445 TYR E CD1 1 
ATOM   13820 C CD2 . TYR E 1 392 ? 109.092 158.683 139.179 1.00 103.87 ? 445 TYR E CD2 1 
ATOM   13821 C CE1 . TYR E 1 392 ? 110.629 157.817 137.058 1.00 101.12 ? 445 TYR E CE1 1 
ATOM   13822 C CE2 . TYR E 1 392 ? 109.929 159.570 138.529 1.00 109.28 ? 445 TYR E CE2 1 
ATOM   13823 C CZ  . TYR E 1 392 ? 110.695 159.131 137.469 1.00 109.75 ? 445 TYR E CZ  1 
ATOM   13824 O OH  . TYR E 1 392 ? 111.531 160.009 136.817 1.00 106.10 ? 445 TYR E OH  1 
ATOM   13825 N N   . TYR E 1 393 ? 106.983 154.233 137.478 1.00 88.91  ? 446 TYR E N   1 
ATOM   13826 C CA  . TYR E 1 393 ? 107.167 153.480 136.244 1.00 86.23  ? 446 TYR E CA  1 
ATOM   13827 C C   . TYR E 1 393 ? 105.864 152.882 135.725 1.00 93.63  ? 446 TYR E C   1 
ATOM   13828 O O   . TYR E 1 393 ? 105.882 151.848 135.049 1.00 95.46  ? 446 TYR E O   1 
ATOM   13829 C CB  . TYR E 1 393 ? 108.214 152.385 136.442 1.00 75.97  ? 446 TYR E CB  1 
ATOM   13830 C CG  . TYR E 1 393 ? 109.621 152.912 136.591 1.00 83.14  ? 446 TYR E CG  1 
ATOM   13831 C CD1 . TYR E 1 393 ? 110.348 153.322 135.484 1.00 86.28  ? 446 TYR E CD1 1 
ATOM   13832 C CD2 . TYR E 1 393 ? 110.222 152.999 137.837 1.00 87.23  ? 446 TYR E CD2 1 
ATOM   13833 C CE1 . TYR E 1 393 ? 111.633 153.806 135.613 1.00 83.97  ? 446 TYR E CE1 1 
ATOM   13834 C CE2 . TYR E 1 393 ? 111.509 153.481 137.975 1.00 87.10  ? 446 TYR E CE2 1 
ATOM   13835 C CZ  . TYR E 1 393 ? 112.209 153.883 136.860 1.00 84.72  ? 446 TYR E CZ  1 
ATOM   13836 O OH  . TYR E 1 393 ? 113.491 154.363 136.992 1.00 86.70  ? 446 TYR E OH  1 
ATOM   13837 N N   . VAL E 1 394 ? 104.734 153.512 136.029 1.00 97.65  ? 447 VAL E N   1 
ATOM   13838 C CA  . VAL E 1 394 ? 103.444 153.088 135.496 1.00 102.18 ? 447 VAL E CA  1 
ATOM   13839 C C   . VAL E 1 394 ? 102.626 154.311 135.097 1.00 96.37  ? 447 VAL E C   1 
ATOM   13840 O O   . VAL E 1 394 ? 102.942 154.988 134.119 1.00 92.82  ? 447 VAL E O   1 
ATOM   13841 C CB  . VAL E 1 394 ? 102.670 152.219 136.505 1.00 102.66 ? 447 VAL E CB  1 
ATOM   13842 C CG1 . VAL E 1 394 ? 101.187 152.217 136.172 1.00 98.63  ? 447 VAL E CG1 1 
ATOM   13843 C CG2 . VAL E 1 394 ? 103.210 150.797 136.508 1.00 94.47  ? 447 VAL E CG2 1 
HETATM 13844 C C1  . NAG F 2 .   ? 144.998 157.257 115.507 1.00 78.67  ? 1   NAG a C1  1 
HETATM 13845 C C2  . NAG F 2 .   ? 144.541 158.683 115.208 1.00 77.84  ? 1   NAG a C2  1 
HETATM 13846 C C3  . NAG F 2 .   ? 145.001 159.097 113.813 1.00 80.87  ? 1   NAG a C3  1 
HETATM 13847 C C4  . NAG F 2 .   ? 146.502 158.892 113.661 1.00 82.50  ? 1   NAG a C4  1 
HETATM 13848 C C5  . NAG F 2 .   ? 146.885 157.466 114.049 1.00 82.00  ? 1   NAG a C5  1 
HETATM 13849 C C6  . NAG F 2 .   ? 148.380 157.242 114.062 1.00 86.16  ? 1   NAG a C6  1 
HETATM 13850 C C7  . NAG F 2 .   ? 142.478 159.962 115.576 1.00 70.95  ? 1   NAG a C7  1 
HETATM 13851 C C8  . NAG F 2 .   ? 140.981 159.906 115.652 1.00 65.79  ? 1   NAG a C8  1 
HETATM 13852 N N2  . NAG F 2 .   ? 143.097 158.802 115.326 1.00 75.13  ? 1   NAG a N2  1 
HETATM 13853 O O3  . NAG F 2 .   ? 144.674 160.465 113.593 1.00 83.57  ? 1   NAG a O3  1 
HETATM 13854 O O4  . NAG F 2 .   ? 146.868 159.085 112.298 1.00 89.38  ? 1   NAG a O4  1 
HETATM 13855 O O5  . NAG F 2 .   ? 146.416 157.173 115.374 1.00 82.10  ? 1   NAG a O5  1 
HETATM 13856 O O6  . NAG F 2 .   ? 148.701 155.911 114.439 1.00 92.57  ? 1   NAG a O6  1 
HETATM 13857 O O7  . NAG F 2 .   ? 143.099 161.008 115.736 1.00 74.45  ? 1   NAG a O7  1 
HETATM 13858 C C1  . NAG F 2 .   ? 147.714 160.231 112.104 1.00 89.67  ? 2   NAG a C1  1 
HETATM 13859 C C2  . NAG F 2 .   ? 148.584 159.954 110.879 1.00 87.89  ? 2   NAG a C2  1 
HETATM 13860 C C3  . NAG F 2 .   ? 149.456 161.165 110.562 1.00 93.11  ? 2   NAG a C3  1 
HETATM 13861 C C4  . NAG F 2 .   ? 148.579 162.396 110.396 1.00 96.66  ? 2   NAG a C4  1 
HETATM 13862 C C5  . NAG F 2 .   ? 147.747 162.594 111.659 1.00 90.68  ? 2   NAG a C5  1 
HETATM 13863 C C6  . NAG F 2 .   ? 146.788 163.758 111.558 1.00 90.37  ? 2   NAG a C6  1 
HETATM 13864 C C7  . NAG F 2 .   ? 149.486 157.777 110.192 1.00 83.28  ? 2   NAG a C7  1 
HETATM 13865 C C8  . NAG F 2 .   ? 150.387 156.635 110.561 1.00 78.95  ? 2   NAG a C8  1 
HETATM 13866 N N2  . NAG F 2 .   ? 149.406 158.772 111.083 1.00 86.15  ? 2   NAG a N2  1 
HETATM 13867 O O3  . NAG F 2 .   ? 150.188 160.919 109.366 1.00 99.47  ? 2   NAG a O3  1 
HETATM 13868 O O4  . NAG F 2 .   ? 149.379 163.551 110.161 1.00 104.07 ? 2   NAG a O4  1 
HETATM 13869 O O5  . NAG F 2 .   ? 146.952 161.421 111.894 1.00 91.99  ? 2   NAG a O5  1 
HETATM 13870 O O6  . NAG F 2 .   ? 146.103 163.975 112.783 1.00 92.53  ? 2   NAG a O6  1 
HETATM 13871 O O7  . NAG F 2 .   ? 148.858 157.796 109.138 1.00 84.16  ? 2   NAG a O7  1 
HETATM 13872 C C1  . BMA F 2 .   ? 149.189 163.987 108.798 1.00 105.85 ? 3   BMA a C1  1 
HETATM 13873 C C2  . BMA F 2 .   ? 149.837 165.358 108.634 1.00 108.22 ? 3   BMA a C2  1 
HETATM 13874 C C3  . BMA F 2 .   ? 149.719 165.831 107.192 1.00 110.28 ? 3   BMA a C3  1 
HETATM 13875 C C4  . BMA F 2 .   ? 150.276 164.781 106.242 1.00 112.35 ? 3   BMA a C4  1 
HETATM 13876 C C5  . BMA F 2 .   ? 149.605 163.435 106.499 1.00 107.89 ? 3   BMA a C5  1 
HETATM 13877 C C6  . BMA F 2 .   ? 150.208 162.317 105.679 1.00 106.13 ? 3   BMA a C6  1 
HETATM 13878 O O2  . BMA F 2 .   ? 151.208 165.286 109.014 1.00 106.98 ? 3   BMA a O2  1 
HETATM 13879 O O3  . BMA F 2 .   ? 150.415 167.062 107.022 1.00 105.90 ? 3   BMA a O3  1 
HETATM 13880 O O4  . BMA F 2 .   ? 150.044 165.169 104.892 1.00 113.93 ? 3   BMA a O4  1 
HETATM 13881 O O5  . BMA F 2 .   ? 149.776 163.065 107.877 1.00 109.86 ? 3   BMA a O5  1 
HETATM 13882 O O6  . BMA F 2 .   ? 151.572 162.124 106.027 1.00 115.82 ? 3   BMA a O6  1 
HETATM 13883 C C1  . MAN F 2 .   ? 149.526 168.146 107.360 1.00 63.27  ? 4   MAN a C1  1 
HETATM 13884 C C2  . MAN F 2 .   ? 149.370 169.041 106.133 1.00 63.27  ? 4   MAN a C2  1 
HETATM 13885 C C3  . MAN F 2 .   ? 150.693 169.716 105.798 1.00 63.27  ? 4   MAN a C3  1 
HETATM 13886 C C4  . MAN F 2 .   ? 151.232 170.454 107.015 1.00 63.27  ? 4   MAN a C4  1 
HETATM 13887 C C5  . MAN F 2 .   ? 151.324 169.498 108.201 1.00 63.27  ? 4   MAN a C5  1 
HETATM 13888 C C6  . MAN F 2 .   ? 151.749 170.183 109.480 1.00 63.27  ? 4   MAN a C6  1 
HETATM 13889 O O2  . MAN F 2 .   ? 148.370 170.023 106.380 1.00 63.27  ? 4   MAN a O2  1 
HETATM 13890 O O3  . MAN F 2 .   ? 150.523 170.619 104.711 1.00 63.27  ? 4   MAN a O3  1 
HETATM 13891 O O4  . MAN F 2 .   ? 152.524 170.984 106.736 1.00 63.27  ? 4   MAN a O4  1 
HETATM 13892 O O5  . MAN F 2 .   ? 150.035 168.915 108.454 1.00 63.27  ? 4   MAN a O5  1 
HETATM 13893 O O6  . MAN F 2 .   ? 151.841 169.260 110.556 1.00 63.27  ? 4   MAN a O6  1 
HETATM 13894 C C1  . MAN F 2 .   ? 152.247 161.360 105.013 1.00 121.24 ? 5   MAN a C1  1 
HETATM 13895 C C2  . MAN F 2 .   ? 153.523 160.806 105.632 1.00 127.04 ? 5   MAN a C2  1 
HETATM 13896 C C3  . MAN F 2 .   ? 154.455 161.949 106.009 1.00 129.47 ? 5   MAN a C3  1 
HETATM 13897 C C4  . MAN F 2 .   ? 154.716 162.840 104.802 1.00 127.43 ? 5   MAN a C4  1 
HETATM 13898 C C5  . MAN F 2 .   ? 153.394 163.299 104.191 1.00 127.43 ? 5   MAN a C5  1 
HETATM 13899 C C6  . MAN F 2 .   ? 153.578 164.068 102.903 1.00 125.77 ? 5   MAN a C6  1 
HETATM 13900 O O2  . MAN F 2 .   ? 154.167 159.934 104.709 1.00 124.18 ? 5   MAN a O2  1 
HETATM 13901 O O3  . MAN F 2 .   ? 155.683 161.436 106.515 1.00 128.91 ? 5   MAN a O3  1 
HETATM 13902 O O4  . MAN F 2 .   ? 155.469 163.982 105.194 1.00 120.73 ? 5   MAN a O4  1 
HETATM 13903 O O5  . MAN F 2 .   ? 152.576 162.159 103.876 1.00 125.62 ? 5   MAN a O5  1 
HETATM 13904 O O6  . MAN F 2 .   ? 152.329 164.438 102.336 1.00 120.39 ? 5   MAN a O6  1 
HETATM 13905 C C1  . NAG G 3 .   ? 123.777 163.402 86.478  1.00 91.43  ? 1   NAG F C1  1 
HETATM 13906 C C2  . NAG G 3 .   ? 122.785 164.516 86.806  1.00 93.81  ? 1   NAG F C2  1 
HETATM 13907 C C3  . NAG G 3 .   ? 123.504 165.861 86.859  1.00 94.80  ? 1   NAG F C3  1 
HETATM 13908 C C4  . NAG G 3 .   ? 124.675 165.786 87.830  1.00 92.64  ? 1   NAG F C4  1 
HETATM 13909 C C5  . NAG G 3 .   ? 125.589 164.624 87.453  1.00 92.63  ? 1   NAG F C5  1 
HETATM 13910 C C6  . NAG G 3 .   ? 126.721 164.412 88.433  1.00 92.62  ? 1   NAG F C6  1 
HETATM 13911 C C7  . NAG G 3 .   ? 120.459 164.154 86.108  1.00 95.18  ? 1   NAG F C7  1 
HETATM 13912 C C8  . NAG G 3 .   ? 119.472 164.252 84.982  1.00 94.91  ? 1   NAG F C8  1 
HETATM 13913 N N2  . NAG G 3 .   ? 121.707 164.550 85.831  1.00 96.64  ? 1   NAG F N2  1 
HETATM 13914 O O3  . NAG G 3 .   ? 122.589 166.871 87.271  1.00 99.52  ? 1   NAG F O3  1 
HETATM 13915 O O4  . NAG G 3 .   ? 125.416 167.002 87.788  1.00 89.71  ? 1   NAG F O4  1 
HETATM 13916 O O5  . NAG G 3 .   ? 124.832 163.404 87.437  1.00 90.46  ? 1   NAG F O5  1 
HETATM 13917 O O6  . NAG G 3 .   ? 126.230 164.086 89.726  1.00 92.62  ? 1   NAG F O6  1 
HETATM 13918 O O7  . NAG G 3 .   ? 120.140 163.738 87.219  1.00 89.76  ? 1   NAG F O7  1 
HETATM 13919 C C1  . NAG G 3 .   ? 125.389 167.606 89.099  1.00 112.82 ? 2   NAG F C1  1 
HETATM 13920 C C2  . NAG G 3 .   ? 126.475 168.678 89.155  1.00 112.82 ? 2   NAG F C2  1 
HETATM 13921 C C3  . NAG G 3 .   ? 126.466 169.358 90.521  1.00 112.82 ? 2   NAG F C3  1 
HETATM 13922 C C4  . NAG G 3 .   ? 125.073 169.901 90.814  1.00 112.82 ? 2   NAG F C4  1 
HETATM 13923 C C5  . NAG G 3 .   ? 124.034 168.791 90.677  1.00 112.82 ? 2   NAG F C5  1 
HETATM 13924 C C6  . NAG G 3 .   ? 122.615 169.290 90.835  1.00 112.82 ? 2   NAG F C6  1 
HETATM 13925 C C7  . NAG G 3 .   ? 128.338 168.133 87.653  1.00 112.82 ? 2   NAG F C7  1 
HETATM 13926 C C8  . NAG G 3 .   ? 129.694 167.501 87.535  1.00 112.82 ? 2   NAG F C8  1 
HETATM 13927 N N2  . NAG G 3 .   ? 127.783 168.109 88.871  1.00 112.82 ? 2   NAG F N2  1 
HETATM 13928 O O3  . NAG G 3 .   ? 127.416 170.418 90.529  1.00 112.82 ? 2   NAG F O3  1 
HETATM 13929 O O4  . NAG G 3 .   ? 125.024 170.427 92.136  1.00 112.82 ? 2   NAG F O4  1 
HETATM 13930 O O5  . NAG G 3 .   ? 124.118 168.201 89.370  1.00 112.82 ? 2   NAG F O5  1 
HETATM 13931 O O6  . NAG G 3 .   ? 121.672 168.243 90.650  1.00 112.82 ? 2   NAG F O6  1 
HETATM 13932 O O7  . NAG G 3 .   ? 127.770 168.640 86.690  1.00 112.82 ? 2   NAG F O7  1 
HETATM 13933 C C1  . NAG H 2 .   ? 160.326 123.964 115.114 1.00 74.44  ? 1   NAG b C1  1 
HETATM 13934 C C2  . NAG H 2 .   ? 161.589 124.773 114.828 1.00 71.61  ? 1   NAG b C2  1 
HETATM 13935 C C3  . NAG H 2 .   ? 162.062 124.515 113.401 1.00 73.67  ? 1   NAG b C3  1 
HETATM 13936 C C4  . NAG H 2 .   ? 162.230 123.019 113.163 1.00 79.55  ? 1   NAG b C4  1 
HETATM 13937 C C5  . NAG H 2 .   ? 160.953 122.273 113.543 1.00 81.48  ? 1   NAG b C5  1 
HETATM 13938 C C6  . NAG H 2 .   ? 161.102 120.771 113.466 1.00 81.53  ? 1   NAG b C6  1 
HETATM 13939 C C7  . NAG H 2 .   ? 162.332 127.053 115.355 1.00 72.45  ? 1   NAG b C7  1 
HETATM 13940 C C8  . NAG H 2 .   ? 161.914 128.483 115.537 1.00 65.67  ? 1   NAG b C8  1 
HETATM 13941 N N2  . NAG H 2 .   ? 161.356 126.193 115.042 1.00 72.63  ? 1   NAG b N2  1 
HETATM 13942 O O3  . NAG H 2 .   ? 163.296 125.187 113.178 1.00 74.87  ? 1   NAG b O3  1 
HETATM 13943 O O4  . NAG H 2 .   ? 162.489 122.782 111.783 1.00 87.62  ? 1   NAG b O4  1 
HETATM 13944 O O5  . NAG H 2 .   ? 160.589 122.579 114.898 1.00 85.02  ? 1   NAG b O5  1 
HETATM 13945 O O6  . NAG H 2 .   ? 159.903 120.112 113.848 1.00 89.18  ? 1   NAG b O6  1 
HETATM 13946 O O7  . NAG H 2 .   ? 163.498 126.694 115.488 1.00 77.14  ? 1   NAG b O7  1 
HETATM 13947 C C1  . NAG H 2 .   ? 163.830 122.294 111.591 1.00 89.84  ? 2   NAG b C1  1 
HETATM 13948 C C2  . NAG H 2 .   ? 163.832 121.392 110.358 1.00 89.87  ? 2   NAG b C2  1 
HETATM 13949 C C3  . NAG H 2 .   ? 165.244 120.888 110.078 1.00 95.48  ? 2   NAG b C3  1 
HETATM 13950 C C4  . NAG H 2 .   ? 166.198 122.067 109.956 1.00 95.82  ? 2   NAG b C4  1 
HETATM 13951 C C5  . NAG H 2 .   ? 166.108 122.939 111.205 1.00 89.79  ? 2   NAG b C5  1 
HETATM 13952 C C6  . NAG H 2 .   ? 166.948 124.193 111.112 1.00 86.57  ? 2   NAG b C6  1 
HETATM 13953 C C7  . NAG H 2 .   ? 161.738 120.202 109.893 1.00 78.70  ? 2   NAG b C7  1 
HETATM 13954 C C8  . NAG H 2 .   ? 160.913 118.983 110.182 1.00 71.49  ? 2   NAG b C8  1 
HETATM 13955 N N2  . NAG H 2 .   ? 162.913 120.278 110.527 1.00 83.47  ? 2   NAG b N2  1 
HETATM 13956 O O3  . NAG H 2 .   ? 165.246 120.129 108.874 1.00 97.97  ? 2   NAG b O3  1 
HETATM 13957 O O4  . NAG H 2 .   ? 167.533 121.596 109.809 1.00 107.86 ? 2   NAG b O4  1 
HETATM 13958 O O5  . NAG H 2 .   ? 164.750 123.369 111.399 1.00 94.79  ? 2   NAG b O5  1 
HETATM 13959 O O6  . NAG H 2 .   ? 166.878 124.954 112.310 1.00 85.20  ? 2   NAG b O6  1 
HETATM 13960 O O7  . NAG H 2 .   ? 161.357 121.077 109.121 1.00 80.69  ? 2   NAG b O7  1 
HETATM 13961 C C1  . BMA H 2 .   ? 168.018 121.939 108.494 1.00 119.22 ? 3   BMA b C1  1 
HETATM 13962 C C2  . BMA H 2 .   ? 169.532 121.753 108.491 1.00 123.71 ? 3   BMA b C2  1 
HETATM 13963 C C3  . BMA H 2 .   ? 170.100 122.055 107.112 1.00 124.20 ? 3   BMA b C3  1 
HETATM 13964 C C4  . BMA H 2 .   ? 169.385 121.230 106.051 1.00 126.91 ? 3   BMA b C4  1 
HETATM 13965 C C5  . BMA H 2 .   ? 167.877 121.439 106.156 1.00 125.10 ? 3   BMA b C5  1 
HETATM 13966 C C6  . BMA H 2 .   ? 167.090 120.564 105.206 1.00 123.54 ? 3   BMA b C6  1 
HETATM 13967 O O2  . BMA H 2 .   ? 169.848 120.417 108.868 1.00 125.71 ? 3   BMA b O2  1 
HETATM 13968 O O3  . BMA H 2 .   ? 171.496 121.774 107.087 1.00 119.21 ? 3   BMA b O3  1 
HETATM 13969 O O4  . BMA H 2 .   ? 169.821 121.616 104.753 1.00 123.93 ? 3   BMA b O4  1 
HETATM 13970 O O5  . BMA H 2 .   ? 167.433 121.115 107.484 1.00 127.43 ? 3   BMA b O5  1 
HETATM 13971 O O6  . BMA H 2 .   ? 167.392 119.187 105.388 1.00 139.58 ? 3   BMA b O6  1 
HETATM 13972 C C1  . MAN H 2 .   ? 172.202 122.779 107.841 1.00 55.95  ? 4   MAN b C1  1 
HETATM 13973 C C2  . MAN H 2 .   ? 173.101 123.551 106.881 1.00 55.95  ? 4   MAN b C2  1 
HETATM 13974 C C3  . MAN H 2 .   ? 174.174 122.632 106.314 1.00 55.95  ? 4   MAN b C3  1 
HETATM 13975 C C4  . MAN H 2 .   ? 174.939 121.952 107.441 1.00 55.95  ? 4   MAN b C4  1 
HETATM 13976 C C5  . MAN H 2 .   ? 173.965 121.248 108.381 1.00 55.95  ? 4   MAN b C5  1 
HETATM 13977 C C6  . MAN H 2 .   ? 174.642 120.648 109.593 1.00 55.95  ? 4   MAN b C6  1 
HETATM 13978 O O2  . MAN H 2 .   ? 173.705 124.644 107.566 1.00 55.95  ? 4   MAN b O2  1 
HETATM 13979 O O3  . MAN H 2 .   ? 175.067 123.373 105.489 1.00 55.95  ? 4   MAN b O3  1 
HETATM 13980 O O4  . MAN H 2 .   ? 175.850 120.996 106.909 1.00 55.95  ? 4   MAN b O4  1 
HETATM 13981 O O5  . MAN H 2 .   ? 172.997 122.190 108.872 1.00 55.95  ? 4   MAN b O5  1 
HETATM 13982 O O6  . MAN H 2 .   ? 173.703 120.013 110.450 1.00 55.95  ? 4   MAN b O6  1 
HETATM 13983 C C1  . MAN H 2 .   ? 166.844 118.453 104.273 1.00 144.28 ? 5   MAN b C1  1 
HETATM 13984 C C2  . MAN H 2 .   ? 166.396 117.081 104.770 1.00 150.67 ? 5   MAN b C2  1 
HETATM 13985 C C3  . MAN H 2 .   ? 167.598 116.260 105.217 1.00 154.63 ? 5   MAN b C3  1 
HETATM 13986 C C4  . MAN H 2 .   ? 168.637 116.193 104.106 1.00 152.03 ? 5   MAN b C4  1 
HETATM 13987 C C5  . MAN H 2 .   ? 168.999 117.603 103.649 1.00 151.14 ? 5   MAN b C5  1 
HETATM 13988 C C6  . MAN H 2 .   ? 169.947 117.616 102.471 1.00 147.50 ? 5   MAN b C6  1 
HETATM 13989 O O2  . MAN H 2 .   ? 165.697 116.401 103.732 1.00 140.10 ? 5   MAN b O2  1 
HETATM 13990 O O3  . MAN H 2 .   ? 167.187 114.947 105.584 1.00 147.79 ? 5   MAN b O3  1 
HETATM 13991 O O4  . MAN H 2 .   ? 169.812 115.537 104.573 1.00 144.95 ? 5   MAN b O4  1 
HETATM 13992 O O5  . MAN H 2 .   ? 167.811 118.296 103.231 1.00 149.81 ? 5   MAN b O5  1 
HETATM 13993 O O6  . MAN H 2 .   ? 170.290 118.944 102.099 1.00 145.31 ? 5   MAN b O6  1 
HETATM 13994 C C1  . NAG I 3 .   ? 159.390 145.999 85.970  1.00 100.18 ? 1   NAG G C1  1 
HETATM 13995 C C2  . NAG I 3 .   ? 160.117 147.341 85.952  1.00 106.64 ? 1   NAG G C2  1 
HETATM 13996 C C3  . NAG I 3 .   ? 161.626 147.119 85.961  1.00 108.48 ? 1   NAG G C3  1 
HETATM 13997 C C4  . NAG I 3 .   ? 162.014 146.240 87.144  1.00 115.91 ? 1   NAG G C4  1 
HETATM 13998 C C5  . NAG I 3 .   ? 161.205 144.946 87.120  1.00 106.89 ? 1   NAG G C5  1 
HETATM 13999 C C6  . NAG I 3 .   ? 161.447 144.075 88.331  1.00 109.48 ? 1   NAG G C6  1 
HETATM 14000 C C7  . NAG I 3 .   ? 158.935 149.210 84.886  1.00 107.72 ? 1   NAG G C7  1 
HETATM 14001 C C8  . NAG I 3 .   ? 158.627 149.909 83.594  1.00 97.58  ? 1   NAG G C8  1 
HETATM 14002 N N2  . NAG I 3 .   ? 159.722 148.131 84.797  1.00 110.44 ? 1   NAG G N2  1 
HETATM 14003 O O3  . NAG I 3 .   ? 162.291 148.375 86.042  1.00 110.96 ? 1   NAG G O3  1 
HETATM 14004 O O4  . NAG I 3 .   ? 163.402 145.924 87.084  1.00 125.30 ? 1   NAG G O4  1 
HETATM 14005 O O5  . NAG I 3 .   ? 159.801 145.248 87.111  1.00 101.84 ? 1   NAG G O5  1 
HETATM 14006 O O6  . NAG I 3 .   ? 161.132 144.766 89.532  1.00 111.23 ? 1   NAG G O6  1 
HETATM 14007 O O7  . NAG I 3 .   ? 158.491 149.605 85.961  1.00 108.94 ? 1   NAG G O7  1 
HETATM 14008 C C1  . NAG I 3 .   ? 164.103 146.611 88.144  1.00 127.04 ? 2   NAG G C1  1 
HETATM 14009 C C2  . NAG I 3 .   ? 165.160 145.670 88.721  1.00 124.53 ? 2   NAG G C2  1 
HETATM 14010 C C3  . NAG I 3 .   ? 165.948 146.378 89.819  1.00 127.46 ? 2   NAG G C3  1 
HETATM 14011 C C4  . NAG I 3 .   ? 166.533 147.675 89.279  1.00 131.66 ? 2   NAG G C4  1 
HETATM 14012 C C5  . NAG I 3 .   ? 165.427 148.537 88.677  1.00 130.33 ? 2   NAG G C5  1 
HETATM 14013 C C6  . NAG I 3 .   ? 165.951 149.795 88.023  1.00 127.17 ? 2   NAG G C6  1 
HETATM 14014 C C7  . NAG I 3 .   ? 165.079 143.239 89.049  1.00 121.19 ? 2   NAG G C7  1 
HETATM 14015 C C8  . NAG I 3 .   ? 164.316 142.091 89.643  1.00 113.66 ? 2   NAG G C8  1 
HETATM 14016 N N2  . NAG I 3 .   ? 164.549 144.454 89.232  1.00 120.52 ? 2   NAG G N2  1 
HETATM 14017 O O3  . NAG I 3 .   ? 166.989 145.526 90.285  1.00 124.14 ? 2   NAG G O3  1 
HETATM 14018 O O4  . NAG I 3 .   ? 167.170 148.398 90.328  1.00 130.26 ? 2   NAG G O4  1 
HETATM 14019 O O5  . NAG I 3 .   ? 164.736 147.798 87.657  1.00 132.68 ? 2   NAG G O5  1 
HETATM 14020 O O6  . NAG I 3 .   ? 164.901 150.557 87.445  1.00 122.82 ? 2   NAG G O6  1 
HETATM 14021 O O7  . NAG I 3 .   ? 166.127 143.073 88.431  1.00 124.81 ? 2   NAG G O7  1 
HETATM 14022 C C1  . NAG J 2 .   ? 133.658 98.707  114.878 1.00 75.12  ? 1   NAG c C1  1 
HETATM 14023 C C2  . NAG J 2 .   ? 134.794 97.770  114.478 1.00 72.48  ? 1   NAG c C2  1 
HETATM 14024 C C3  . NAG J 2 .   ? 134.565 97.248  113.062 1.00 78.98  ? 1   NAG c C3  1 
HETATM 14025 C C4  . NAG J 2 .   ? 133.181 96.620  112.939 1.00 83.45  ? 1   NAG c C4  1 
HETATM 14026 C C5  . NAG J 2 .   ? 132.110 97.587  113.439 1.00 81.44  ? 1   NAG c C5  1 
HETATM 14027 C C6  . NAG J 2 .   ? 130.733 96.966  113.491 1.00 81.11  ? 1   NAG c C6  1 
HETATM 14028 C C7  . NAG J 2 .   ? 137.205 97.813  114.933 1.00 75.00  ? 1   NAG c C7  1 
HETATM 14029 C C8  . NAG J 2 .   ? 138.443 98.659  114.982 1.00 69.31  ? 1   NAG c C8  1 
HETATM 14030 N N2  . NAG J 2 .   ? 136.080 98.441  114.574 1.00 70.77  ? 1   NAG c N2  1 
HETATM 14031 O O3  . NAG J 2 .   ? 135.566 96.288  112.745 1.00 80.42  ? 1   NAG c O3  1 
HETATM 14032 O O4  . NAG J 2 .   ? 132.912 96.342  111.568 1.00 89.17  ? 1   NAG c O4  1 
HETATM 14033 O O5  . NAG J 2 .   ? 132.413 98.018  114.774 1.00 80.35  ? 1   NAG c O5  1 
HETATM 14034 O O6  . NAG J 2 .   ? 129.780 97.870  114.031 1.00 88.95  ? 1   NAG c O6  1 
HETATM 14035 O O7  . NAG J 2 .   ? 137.224 96.617  115.207 1.00 81.95  ? 1   NAG c O7  1 
HETATM 14036 C C1  . NAG J 2 .   ? 132.771 94.935  111.297 1.00 88.65  ? 2   NAG c C1  1 
HETATM 14037 C C2  . NAG J 2 .   ? 131.967 94.790  110.007 1.00 91.07  ? 2   NAG c C2  1 
HETATM 14038 C C3  . NAG J 2 .   ? 131.840 93.319  109.625 1.00 94.37  ? 2   NAG c C3  1 
HETATM 14039 C C4  . NAG J 2 .   ? 133.220 92.687  109.538 1.00 95.05  ? 2   NAG c C4  1 
HETATM 14040 C C5  . NAG J 2 .   ? 133.959 92.895  110.856 1.00 89.41  ? 2   NAG c C5  1 
HETATM 14041 C C6  . NAG J 2 .   ? 135.378 92.375  110.831 1.00 85.87  ? 2   NAG c C6  1 
HETATM 14042 C C7  . NAG J 2 .   ? 130.400 96.666  109.788 1.00 89.22  ? 2   NAG c C7  1 
HETATM 14043 C C8  . NAG J 2 .   ? 128.987 97.133  109.987 1.00 82.88  ? 2   NAG c C8  1 
HETATM 14044 N N2  . NAG J 2 .   ? 130.654 95.401  110.140 1.00 91.34  ? 2   NAG c N2  1 
HETATM 14045 O O3  . NAG J 2 .   ? 131.173 93.208  108.372 1.00 94.49  ? 2   NAG c O3  1 
HETATM 14046 O O4  . NAG J 2 .   ? 133.100 91.293  109.269 1.00 104.43 ? 2   NAG c O4  1 
HETATM 14047 O O5  . NAG J 2 .   ? 134.040 94.300  111.146 1.00 89.99  ? 2   NAG c O5  1 
HETATM 14048 O O6  . NAG J 2 .   ? 136.014 92.546  112.090 1.00 90.91  ? 2   NAG c O6  1 
HETATM 14049 O O7  . NAG J 2 .   ? 131.270 97.403  109.334 1.00 88.55  ? 2   NAG c O7  1 
HETATM 14050 C C1  . BMA J 2 .   ? 133.696 90.984  107.989 1.00 109.17 ? 3   BMA c C1  1 
HETATM 14051 C C2  . BMA J 2 .   ? 134.019 89.493  107.967 1.00 112.13 ? 3   BMA c C2  1 
HETATM 14052 C C3  . BMA J 2 .   ? 134.629 89.104  106.627 1.00 115.67 ? 3   BMA c C3  1 
HETATM 14053 C C4  . BMA J 2 .   ? 133.735 89.555  105.481 1.00 111.29 ? 3   BMA c C4  1 
HETATM 14054 C C5  . BMA J 2 .   ? 133.402 91.038  105.614 1.00 106.32 ? 3   BMA c C5  1 
HETATM 14055 C C6  . BMA J 2 .   ? 132.403 91.504  104.580 1.00 102.55 ? 3   BMA c C6  1 
HETATM 14056 O O2  . BMA J 2 .   ? 132.830 88.745  108.200 1.00 109.07 ? 3   BMA c O2  1 
HETATM 14057 O O3  . BMA J 2 .   ? 134.802 87.692  106.554 1.00 116.44 ? 3   BMA c O3  1 
HETATM 14058 O O4  . BMA J 2 .   ? 134.387 89.333  104.235 1.00 110.13 ? 3   BMA c O4  1 
HETATM 14059 O O5  . BMA J 2 .   ? 132.820 91.295  106.903 1.00 109.41 ? 3   BMA c O5  1 
HETATM 14060 O O6  . BMA J 2 .   ? 131.351 90.561  104.424 1.00 112.23 ? 3   BMA c O6  1 
HETATM 14061 C C1  . MAN J 2 .   ? 135.689 87.212  107.581 1.00 95.37  ? 4   MAN c C1  1 
HETATM 14062 C C2  . MAN J 2 .   ? 136.882 86.541  106.913 1.00 95.37  ? 4   MAN c C2  1 
HETATM 14063 C C3  . MAN J 2 .   ? 136.422 85.319  106.130 1.00 95.37  ? 4   MAN c C3  1 
HETATM 14064 C C4  . MAN J 2 .   ? 135.623 84.382  107.026 1.00 95.37  ? 4   MAN c C4  1 
HETATM 14065 C C5  . MAN J 2 .   ? 134.490 85.146  107.705 1.00 95.37  ? 4   MAN c C5  1 
HETATM 14066 C C6  . MAN J 2 .   ? 133.732 84.308  108.710 1.00 95.37  ? 4   MAN c C6  1 
HETATM 14067 O O2  . MAN J 2 .   ? 137.831 86.158  107.903 1.00 95.37  ? 4   MAN c O2  1 
HETATM 14068 O O3  . MAN J 2 .   ? 137.546 84.635  105.585 1.00 95.37  ? 4   MAN c O3  1 
HETATM 14069 O O4  . MAN J 2 .   ? 135.073 83.320  106.253 1.00 95.37  ? 4   MAN c O4  1 
HETATM 14070 O O5  . MAN J 2 .   ? 135.024 86.272  108.423 1.00 95.37  ? 4   MAN c O5  1 
HETATM 14071 O O6  . MAN J 2 .   ? 132.698 85.056  109.335 1.00 95.37  ? 4   MAN c O6  1 
HETATM 14072 C C1  . MAN J 2 .   ? 130.352 91.120  103.551 1.00 114.23 ? 5   MAN c C1  1 
HETATM 14073 C C2  . MAN J 2 .   ? 129.227 91.661  104.425 1.00 118.73 ? 5   MAN c C2  1 
HETATM 14074 C C3  . MAN J 2 .   ? 128.545 90.521  105.166 1.00 123.69 ? 5   MAN c C3  1 
HETATM 14075 C C4  . MAN J 2 .   ? 128.078 89.456  104.184 1.00 124.15 ? 5   MAN c C4  1 
HETATM 14076 C C5  . MAN J 2 .   ? 129.244 89.003  103.310 1.00 123.23 ? 5   MAN c C5  1 
HETATM 14077 C C6  . MAN J 2 .   ? 128.827 88.039  102.222 1.00 117.49 ? 5   MAN c C6  1 
HETATM 14078 O O2  . MAN J 2 .   ? 128.283 92.352  103.613 1.00 110.50 ? 5   MAN c O2  1 
HETATM 14079 O O3  . MAN J 2 .   ? 127.442 91.014  105.919 1.00 118.22 ? 5   MAN c O3  1 
HETATM 14080 O O4  . MAN J 2 .   ? 127.559 88.334  104.891 1.00 117.54 ? 5   MAN c O4  1 
HETATM 14081 O O5  . MAN J 2 .   ? 129.829 90.139  102.651 1.00 121.51 ? 5   MAN c O5  1 
HETATM 14082 O O6  . MAN J 2 .   ? 129.933 87.646  101.422 1.00 111.41 ? 5   MAN c O6  1 
HETATM 14083 C C1  . NAG K 3 .   ? 152.825 106.471 85.483  1.00 98.26  ? 1   NAG H C1  1 
HETATM 14084 C C2  . NAG K 3 .   ? 154.291 106.052 85.563  1.00 102.82 ? 1   NAG H C2  1 
HETATM 14085 C C3  . NAG K 3 .   ? 154.402 104.530 85.577  1.00 108.39 ? 1   NAG H C3  1 
HETATM 14086 C C4  . NAG K 3 .   ? 153.540 103.947 86.689  1.00 113.56 ? 1   NAG H C4  1 
HETATM 14087 C C5  . NAG K 3 .   ? 152.108 104.463 86.569  1.00 110.84 ? 1   NAG H C5  1 
HETATM 14088 C C6  . NAG K 3 .   ? 151.221 104.028 87.713  1.00 110.90 ? 1   NAG H C6  1 
HETATM 14089 C C7  . NAG K 3 .   ? 155.984 107.554 84.615  1.00 104.08 ? 1   NAG H C7  1 
HETATM 14090 C C8  . NAG K 3 .   ? 156.671 108.018 83.364  1.00 102.22 ? 1   NAG H C8  1 
HETATM 14091 N N2  . NAG K 3 .   ? 155.050 106.610 84.456  1.00 102.33 ? 1   NAG H N2  1 
HETATM 14092 O O3  . NAG K 3 .   ? 155.763 104.156 85.767  1.00 111.76 ? 1   NAG H O3  1 
HETATM 14093 O O4  . NAG K 3 .   ? 153.519 102.527 86.578  1.00 119.23 ? 1   NAG H O4  1 
HETATM 14094 O O5  . NAG K 3 .   ? 152.105 105.900 86.574  1.00 106.42 ? 1   NAG H O5  1 
HETATM 14095 O O6  . NAG K 3 .   ? 151.680 104.552 88.951  1.00 113.89 ? 1   NAG H O6  1 
HETATM 14096 O O7  . NAG K 3 .   ? 156.263 108.012 85.719  1.00 106.16 ? 1   NAG H O7  1 
HETATM 14097 C C1  . NAG K 3 .   ? 154.162 101.913 87.711  1.00 122.43 ? 2   NAG H C1  1 
HETATM 14098 C C2  . NAG K 3 .   ? 153.681 100.465 87.790  1.00 125.63 ? 2   NAG H C2  1 
HETATM 14099 C C3  . NAG K 3 .   ? 154.364 99.746  88.949  1.00 128.24 ? 2   NAG H C3  1 
HETATM 14100 C C4  . NAG K 3 .   ? 155.875 99.867  88.810  1.00 132.70 ? 2   NAG H C4  1 
HETATM 14101 C C5  . NAG K 3 .   ? 156.269 101.337 88.700  1.00 129.88 ? 2   NAG H C5  1 
HETATM 14102 C C6  . NAG K 3 .   ? 157.749 101.533 88.459  1.00 129.28 ? 2   NAG H C6  1 
HETATM 14103 C C7  . NAG K 3 .   ? 151.444 99.773  87.057  1.00 120.76 ? 2   NAG H C7  1 
HETATM 14104 C C8  . NAG K 3 .   ? 149.973 99.812  87.352  1.00 111.85 ? 2   NAG H C8  1 
HETATM 14105 N N2  . NAG K 3 .   ? 152.235 100.407 87.930  1.00 125.20 ? 2   NAG H N2  1 
HETATM 14106 O O3  . NAG K 3 .   ? 153.982 98.374  88.949  1.00 125.22 ? 2   NAG H O3  1 
HETATM 14107 O O4  . NAG K 3 .   ? 156.519 99.290  89.941  1.00 134.46 ? 2   NAG H O4  1 
HETATM 14108 O O5  . NAG K 3 .   ? 155.586 101.939 87.589  1.00 127.10 ? 2   NAG H O5  1 
HETATM 14109 O O6  . NAG K 3 .   ? 158.092 102.912 88.433  1.00 125.35 ? 2   NAG H O6  1 
HETATM 14110 O O7  . NAG K 3 .   ? 151.894 99.194  86.072  1.00 120.60 ? 2   NAG H O7  1 
HETATM 14111 C C1  . NAG L 2 .   ? 102.338 116.935 116.754 1.00 75.68  ? 1   NAG d C1  1 
HETATM 14112 C C2  . NAG L 2 .   ? 101.808 115.526 116.501 1.00 75.00  ? 1   NAG d C2  1 
HETATM 14113 C C3  . NAG L 2 .   ? 101.157 115.453 115.123 1.00 79.83  ? 1   NAG d C3  1 
HETATM 14114 C C4  . NAG L 2 .   ? 100.099 116.539 114.974 1.00 85.94  ? 1   NAG d C4  1 
HETATM 14115 C C5  . NAG L 2 .   ? 100.691 117.904 115.314 1.00 85.04  ? 1   NAG d C5  1 
HETATM 14116 C C6  . NAG L 2 .   ? 99.660  119.010 115.323 1.00 85.70  ? 1   NAG d C6  1 
HETATM 14117 C C7  . NAG L 2 .   ? 102.649 113.243 116.836 1.00 78.24  ? 1   NAG d C7  1 
HETATM 14118 C C8  . NAG L 2 .   ? 103.867 112.371 116.930 1.00 72.77  ? 1   NAG d C8  1 
HETATM 14119 N N2  . NAG L 2 .   ? 102.874 114.544 116.618 1.00 75.46  ? 1   NAG d N2  1 
HETATM 14120 O O3  . NAG L 2 .   ? 100.563 114.172 114.941 1.00 84.75  ? 1   NAG d O3  1 
HETATM 14121 O O4  . NAG L 2 .   ? 99.650  116.577 113.622 1.00 94.72  ? 1   NAG d O4  1 
HETATM 14122 O O5  . NAG L 2 .   ? 101.273 117.875 116.626 1.00 81.19  ? 1   NAG d O5  1 
HETATM 14123 O O6  . NAG L 2 .   ? 100.244 120.260 115.659 1.00 86.80  ? 1   NAG d O6  1 
HETATM 14124 O O7  . NAG L 2 .   ? 101.515 112.788 116.950 1.00 84.39  ? 1   NAG d O7  1 
HETATM 14125 C C1  . NAG L 2 .   ? 98.258  116.234 113.502 1.00 94.95  ? 2   NAG d C1  1 
HETATM 14126 C C2  . NAG L 2 .   ? 97.716  116.930 112.256 1.00 91.94  ? 2   NAG d C2  1 
HETATM 14127 C C3  . NAG L 2 .   ? 96.251  116.561 112.040 1.00 95.83  ? 2   NAG d C3  1 
HETATM 14128 C C4  . NAG L 2 .   ? 96.107  115.047 111.985 1.00 99.85  ? 2   NAG d C4  1 
HETATM 14129 C C5  . NAG L 2 .   ? 96.693  114.432 113.252 1.00 101.17 ? 2   NAG d C5  1 
HETATM 14130 C C6  . NAG L 2 .   ? 96.670  112.920 113.242 1.00 95.92  ? 2   NAG d C6  1 
HETATM 14131 C C7  . NAG L 2 .   ? 98.029  119.165 111.290 1.00 89.01  ? 2   NAG d C7  1 
HETATM 14132 C C8  . NAG L 2 .   ? 98.183  120.630 111.577 1.00 83.85  ? 2   NAG d C8  1 
HETATM 14133 N N2  . NAG L 2 .   ? 97.874  118.372 112.356 1.00 90.80  ? 2   NAG d N2  1 
HETATM 14134 O O3  . NAG L 2 .   ? 95.788  117.141 110.825 1.00 101.70 ? 2   NAG d O3  1 
HETATM 14135 O O4  . NAG L 2 .   ? 94.735  114.684 111.866 1.00 104.02 ? 2   NAG d O4  1 
HETATM 14136 O O5  . NAG L 2 .   ? 98.069  114.824 113.385 1.00 101.53 ? 2   NAG d O5  1 
HETATM 14137 O O6  . NAG L 2 .   ? 97.159  112.386 114.464 1.00 91.01  ? 2   NAG d O6  1 
HETATM 14138 O O7  . NAG L 2 .   ? 98.044  118.722 110.146 1.00 85.13  ? 2   NAG d O7  1 
HETATM 14139 C C1  . BMA L 2 .   ? 94.502  114.186 110.531 1.00 105.62 ? 3   BMA d C1  1 
HETATM 14140 C C2  . BMA L 2 .   ? 93.239  113.330 110.538 1.00 110.12 ? 3   BMA d C2  1 
HETATM 14141 C C3  . BMA L 2 .   ? 92.942  112.820 109.135 1.00 113.28 ? 3   BMA d C3  1 
HETATM 14142 C C4  . BMA L 2 .   ? 92.881  113.979 108.148 1.00 114.80 ? 3   BMA d C4  1 
HETATM 14143 C C5  . BMA L 2 .   ? 94.151  114.819 108.247 1.00 111.08 ? 3   BMA d C5  1 
HETATM 14144 C C6  . BMA L 2 .   ? 94.105  116.061 107.384 1.00 109.34 ? 3   BMA d C6  1 
HETATM 14145 O O2  . BMA L 2 .   ? 92.143  114.099 111.021 1.00 107.05 ? 3   BMA d O2  1 
HETATM 14146 O O3  . BMA L 2 .   ? 91.713  112.101 109.123 1.00 109.75 ? 3   BMA d O3  1 
HETATM 14147 O O4  . BMA L 2 .   ? 92.751  113.484 106.820 1.00 112.32 ? 3   BMA d O4  1 
HETATM 14148 O O5  . BMA L 2 .   ? 94.340  115.261 109.601 1.00 111.56 ? 3   BMA d O5  1 
HETATM 14149 O O6  . BMA L 2 .   ? 92.893  116.778 107.580 1.00 117.18 ? 3   BMA d O6  1 
HETATM 14150 C C1  . MAN L 2 .   ? 91.911  110.827 109.770 1.00 18.73  ? 4   MAN d C1  1 
HETATM 14151 C C2  . MAN L 2 .   ? 91.914  109.739 108.699 1.00 18.73  ? 4   MAN d C2  1 
HETATM 14152 C C3  . MAN L 2 .   ? 90.543  109.636 108.045 1.00 18.73  ? 4   MAN d C3  1 
HETATM 14153 C C4  . MAN L 2 .   ? 89.464  109.441 109.102 1.00 18.73  ? 4   MAN d C4  1 
HETATM 14154 C C5  . MAN L 2 .   ? 89.558  110.546 110.150 1.00 18.73  ? 4   MAN d C5  1 
HETATM 14155 C C6  . MAN L 2 .   ? 88.590  110.355 111.296 1.00 18.73  ? 4   MAN d C6  1 
HETATM 14156 O O2  . MAN L 2 .   ? 92.272  108.491 109.285 1.00 18.73  ? 4   MAN d O2  1 
HETATM 14157 O O3  . MAN L 2 .   ? 90.521  108.555 107.119 1.00 18.73  ? 4   MAN d O3  1 
HETATM 14158 O O4  . MAN L 2 .   ? 88.175  109.478 108.498 1.00 18.73  ? 4   MAN d O4  1 
HETATM 14159 O O5  . MAN L 2 .   ? 90.876  110.561 110.722 1.00 18.73  ? 4   MAN d O5  1 
HETATM 14160 O O6  . MAN L 2 .   ? 88.673  111.424 112.228 1.00 18.73  ? 4   MAN d O6  1 
HETATM 14161 C C1  . MAN L 2 .   ? 92.788  117.846 106.615 1.00 119.45 ? 5   MAN d C1  1 
HETATM 14162 C C2  . MAN L 2 .   ? 91.612  118.728 107.023 1.00 119.74 ? 5   MAN d C2  1 
HETATM 14163 C C3  . MAN L 2 .   ? 90.309  117.950 106.911 1.00 118.84 ? 5   MAN d C3  1 
HETATM 14164 C C4  . MAN L 2 .   ? 90.159  117.370 105.511 1.00 123.25 ? 5   MAN d C4  1 
HETATM 14165 C C5  . MAN L 2 .   ? 91.392  116.545 105.154 1.00 122.67 ? 5   MAN d C5  1 
HETATM 14166 C C6  . MAN L 2 .   ? 91.375  116.038 103.730 1.00 117.76 ? 5   MAN d C6  1 
HETATM 14167 O O2  . MAN L 2 .   ? 91.566  119.882 106.190 1.00 117.19 ? 5   MAN d O2  1 
HETATM 14168 O O3  . MAN L 2 .   ? 89.204  118.794 107.216 1.00 111.64 ? 5   MAN d O3  1 
HETATM 14169 O O4  . MAN L 2 .   ? 89.005  116.539 105.449 1.00 116.48 ? 5   MAN d O4  1 
HETATM 14170 O O5  . MAN L 2 .   ? 92.575  117.351 105.290 1.00 119.89 ? 5   MAN d O5  1 
HETATM 14171 O O6  . MAN L 2 .   ? 92.555  115.308 103.425 1.00 106.91 ? 5   MAN d O6  1 
HETATM 14172 C C1  . NAG M 3 .   ? 113.874 100.469 87.034  1.00 90.45  ? 1   NAG I C1  1 
HETATM 14173 C C2  . NAG M 3 .   ? 114.024 98.965  87.260  1.00 89.43  ? 1   NAG I C2  1 
HETATM 14174 C C3  . NAG M 3 .   ? 112.657 98.324  87.478  1.00 96.15  ? 1   NAG I C3  1 
HETATM 14175 C C4  . NAG M 3 .   ? 111.931 99.031  88.613  1.00 100.81 ? 1   NAG I C4  1 
HETATM 14176 C C5  . NAG M 3 .   ? 111.835 100.521 88.298  1.00 100.10 ? 1   NAG I C5  1 
HETATM 14177 C C6  . NAG M 3 .   ? 111.187 101.331 89.399  1.00 92.95  ? 1   NAG I C6  1 
HETATM 14178 C C7  . NAG M 3 .   ? 115.831 97.631  86.272  1.00 93.87  ? 1   NAG I C7  1 
HETATM 14179 C C8  . NAG M 3 .   ? 116.404 97.061  85.007  1.00 86.88  ? 1   NAG I C8  1 
HETATM 14180 N N2  . NAG M 3 .   ? 114.708 98.344  86.138  1.00 91.48  ? 1   NAG I N2  1 
HETATM 14181 O O3  . NAG M 3 .   ? 112.819 96.943  87.784  1.00 99.30  ? 1   NAG I O3  1 
HETATM 14182 O O4  . NAG M 3 .   ? 110.629 98.481  88.794  1.00 100.37 ? 1   NAG I O4  1 
HETATM 14183 O O5  . NAG M 3 .   ? 113.158 101.050 88.124  1.00 97.55  ? 1   NAG I O5  1 
HETATM 14184 O O6  . NAG M 3 .   ? 111.904 101.215 90.620  1.00 91.37  ? 1   NAG I O6  1 
HETATM 14185 O O7  . NAG M 3 .   ? 116.361 97.452  87.366  1.00 93.44  ? 1   NAG I O7  1 
HETATM 14186 C C1  . NAG M 3 .   ? 110.544 97.992  90.153  1.00 44.65  ? 2   NAG I C1  1 
HETATM 14187 C C2  . NAG M 3 .   ? 109.211 97.273  90.356  1.00 44.65  ? 2   NAG I C2  1 
HETATM 14188 C C3  . NAG M 3 .   ? 109.130 96.715  91.774  1.00 44.65  ? 2   NAG I C3  1 
HETATM 14189 C C4  . NAG M 3 .   ? 110.341 95.836  92.057  1.00 44.65  ? 2   NAG I C4  1 
HETATM 14190 C C5  . NAG M 3 .   ? 111.626 96.610  91.781  1.00 44.65  ? 2   NAG I C5  1 
HETATM 14191 C C6  . NAG M 3 .   ? 112.871 95.765  91.934  1.00 44.65  ? 2   NAG I C6  1 
HETATM 14192 C C7  . NAG M 3 .   ? 107.630 98.409  88.861  1.00 44.65  ? 2   NAG I C7  1 
HETATM 14193 C C8  . NAG M 3 .   ? 106.469 99.356  88.771  1.00 44.65  ? 2   NAG I C8  1 
HETATM 14194 N N2  . NAG M 3 .   ? 108.094 98.165  90.092  1.00 44.65  ? 2   NAG I N2  1 
HETATM 14195 O O3  . NAG M 3 .   ? 107.931 95.960  91.922  1.00 44.65  ? 2   NAG I O3  1 
HETATM 14196 O O4  . NAG M 3 .   ? 110.334 95.415  93.417  1.00 44.65  ? 2   NAG I O4  1 
HETATM 14197 O O5  . NAG M 3 .   ? 111.620 97.091  90.428  1.00 44.65  ? 2   NAG I O5  1 
HETATM 14198 O O6  . NAG M 3 .   ? 114.045 96.527  91.690  1.00 44.65  ? 2   NAG I O6  1 
HETATM 14199 O O7  . NAG M 3 .   ? 108.125 97.892  87.864  1.00 44.65  ? 2   NAG I O7  1 
HETATM 14200 C C1  . NAG N 2 .   ? 108.742 153.296 115.730 1.00 67.46  ? 1   NAG e C1  1 
HETATM 14201 C C2  . NAG N 2 .   ? 107.240 153.511 115.554 1.00 65.62  ? 1   NAG e C2  1 
HETATM 14202 C C3  . NAG N 2 .   ? 106.941 154.003 114.140 1.00 71.71  ? 1   NAG e C3  1 
HETATM 14203 C C4  . NAG N 2 .   ? 107.781 155.232 113.813 1.00 75.42  ? 1   NAG e C4  1 
HETATM 14204 C C5  . NAG N 2 .   ? 109.256 154.940 114.071 1.00 77.29  ? 1   NAG e C5  1 
HETATM 14205 C C6  . NAG N 2 .   ? 110.142 156.151 113.885 1.00 75.22  ? 1   NAG e C6  1 
HETATM 14206 C C7  . NAG N 2 .   ? 105.240 152.274 116.258 1.00 71.34  ? 1   NAG e C7  1 
HETATM 14207 C C8  . NAG N 2 .   ? 104.638 150.919 116.496 1.00 64.84  ? 1   NAG e C8  1 
HETATM 14208 N N2  . NAG N 2 .   ? 106.508 152.286 115.835 1.00 68.57  ? 1   NAG e N2  1 
HETATM 14209 O O3  . NAG N 2 .   ? 105.558 154.320 114.030 1.00 71.33  ? 1   NAG e O3  1 
HETATM 14210 O O4  . NAG N 2 .   ? 107.631 155.558 112.435 1.00 81.56  ? 1   NAG e O4  1 
HETATM 14211 O O5  . NAG N 2 .   ? 109.436 154.504 115.426 1.00 75.74  ? 1   NAG e O5  1 
HETATM 14212 O O6  . NAG N 2 .   ? 111.509 155.830 114.098 1.00 76.90  ? 1   NAG e O6  1 
HETATM 14213 O O7  . NAG N 2 .   ? 104.605 153.308 116.442 1.00 77.89  ? 1   NAG e O7  1 
HETATM 14214 C C1  . NAG N 2 .   ? 106.955 156.811 112.240 1.00 84.49  ? 2   NAG e C1  1 
HETATM 14215 C C2  . NAG N 2 .   ? 107.579 157.493 111.023 1.00 84.69  ? 2   NAG e C2  1 
HETATM 14216 C C3  . NAG N 2 .   ? 106.843 158.792 110.708 1.00 88.88  ? 2   NAG e C3  1 
HETATM 14217 C C4  . NAG N 2 .   ? 105.360 158.507 110.526 1.00 87.85  ? 2   NAG e C4  1 
HETATM 14218 C C5  . NAG N 2 .   ? 104.824 157.831 111.784 1.00 84.14  ? 2   NAG e C5  1 
HETATM 14219 C C6  . NAG N 2 .   ? 103.366 157.442 111.681 1.00 83.36  ? 2   NAG e C6  1 
HETATM 14220 C C7  . NAG N 2 .   ? 109.940 157.378 110.367 1.00 82.87  ? 2   NAG e C7  1 
HETATM 14221 C C8  . NAG N 2 .   ? 111.352 157.720 110.744 1.00 78.90  ? 2   NAG e C8  1 
HETATM 14222 N N2  . NAG N 2 .   ? 108.994 157.746 111.238 1.00 80.34  ? 2   NAG e N2  1 
HETATM 14223 O O3  . NAG N 2 .   ? 107.380 159.370 109.523 1.00 91.18  ? 2   NAG e O3  1 
HETATM 14224 O O4  . NAG N 2 .   ? 104.649 159.714 110.265 1.00 99.39  ? 2   NAG e O4  1 
HETATM 14225 O O5  . NAG N 2 .   ? 105.557 156.618 112.020 1.00 88.12  ? 2   NAG e O5  1 
HETATM 14226 O O6  . NAG N 2 .   ? 102.905 156.834 112.879 1.00 85.10  ? 2   NAG e O6  1 
HETATM 14227 O O7  . NAG N 2 .   ? 109.671 156.792 109.323 1.00 85.72  ? 2   NAG e O7  1 
HETATM 14228 C C1  . BMA N 2 .   ? 103.995 159.593 108.978 1.00 105.13 ? 3   BMA e C1  1 
HETATM 14229 C C2  . BMA N 2 .   ? 102.726 160.442 109.003 1.00 108.28 ? 3   BMA e C2  1 
HETATM 14230 C C3  . BMA N 2 .   ? 102.010 160.349 107.663 1.00 111.12 ? 3   BMA e C3  1 
HETATM 14231 C C4  . BMA N 2 .   ? 102.956 160.711 106.527 1.00 111.92 ? 3   BMA e C4  1 
HETATM 14232 C C5  . BMA N 2 .   ? 104.225 159.866 106.613 1.00 108.11 ? 3   BMA e C5  1 
HETATM 14233 C C6  . BMA N 2 .   ? 105.264 160.251 105.584 1.00 107.66 ? 3   BMA e C6  1 
HETATM 14234 O O2  . BMA N 2 .   ? 103.062 161.796 109.286 1.00 104.20 ? 3   BMA e O2  1 
HETATM 14235 O O3  . BMA N 2 .   ? 100.876 161.211 107.651 1.00 101.56 ? 3   BMA e O3  1 
HETATM 14236 O O4  . BMA N 2 .   ? 102.325 160.478 105.272 1.00 111.21 ? 3   BMA e O4  1 
HETATM 14237 O O5  . BMA N 2 .   ? 104.833 160.031 107.905 1.00 110.61 ? 3   BMA e O5  1 
HETATM 14238 O O6  . BMA N 2 .   ? 105.560 161.640 105.637 1.00 119.55 ? 3   BMA e O6  1 
HETATM 14239 C C1  . MAN N 2 .   ? 99.755  160.514 108.229 1.00 91.99  ? 4   MAN e C1  1 
HETATM 14240 C C2  . MAN N 2 .   ? 98.516  160.828 107.400 1.00 91.99  ? 4   MAN e C2  1 
HETATM 14241 C C3  . MAN N 2 .   ? 98.185  162.311 107.495 1.00 91.99  ? 4   MAN e C3  1 
HETATM 14242 C C4  . MAN N 2 .   ? 98.053  162.731 108.952 1.00 91.99  ? 4   MAN e C4  1 
HETATM 14243 C C5  . MAN N 2 .   ? 99.306  162.331 109.726 1.00 91.99  ? 4   MAN e C5  1 
HETATM 14244 C C6  . MAN N 2 .   ? 99.196  162.602 111.210 1.00 91.99  ? 4   MAN e C6  1 
HETATM 14245 O O2  . MAN N 2 .   ? 97.418  160.053 107.870 1.00 91.99  ? 4   MAN e O2  1 
HETATM 14246 O O3  . MAN N 2 .   ? 96.979  162.590 106.791 1.00 91.99  ? 4   MAN e O3  1 
HETATM 14247 O O4  . MAN N 2 .   ? 97.879  164.141 109.040 1.00 91.99  ? 4   MAN e O4  1 
HETATM 14248 O O5  . MAN N 2 .   ? 99.538  160.920 109.582 1.00 91.99  ? 4   MAN e O5  1 
HETATM 14249 O O6  . MAN N 2 .   ? 100.380 162.217 111.896 1.00 91.99  ? 4   MAN e O6  1 
HETATM 14250 C C1  . MAN N 2 .   ? 106.795 161.888 104.933 1.00 128.29 ? 5   MAN e C1  1 
HETATM 14251 C C2  . MAN N 2 .   ? 107.307 163.268 105.334 1.00 132.56 ? 5   MAN e C2  1 
HETATM 14252 C C3  . MAN N 2 .   ? 106.350 164.348 104.848 1.00 132.85 ? 5   MAN e C3  1 
HETATM 14253 C C4  . MAN N 2 .   ? 106.110 164.207 103.351 1.00 132.91 ? 5   MAN e C4  1 
HETATM 14254 C C5  . MAN N 2 .   ? 105.642 162.790 103.032 1.00 135.22 ? 5   MAN e C5  1 
HETATM 14255 C C6  . MAN N 2 .   ? 105.489 162.536 101.550 1.00 129.28 ? 5   MAN e C6  1 
HETATM 14256 O O2  . MAN N 2 .   ? 108.602 163.476 104.780 1.00 130.49 ? 5   MAN e O2  1 
HETATM 14257 O O3  . MAN N 2 .   ? 106.874 165.639 105.142 1.00 125.58 ? 5   MAN e O3  1 
HETATM 14258 O O4  . MAN N 2 .   ? 105.116 165.134 102.925 1.00 129.58 ? 5   MAN e O4  1 
HETATM 14259 O O5  . MAN N 2 .   ? 106.606 161.840 103.517 1.00 133.08 ? 5   MAN e O5  1 
HETATM 14260 O O6  . MAN N 2 .   ? 105.044 161.210 101.296 1.00 114.92 ? 5   MAN e O6  1 
HETATM 14261 C C1  . NAG O 3 .   ? 96.222  135.653 87.309  1.00 87.01  ? 1   NAG J C1  1 
HETATM 14262 C C2  . NAG O 3 .   ? 94.780  135.164 87.416  1.00 94.08  ? 1   NAG J C2  1 
HETATM 14263 C C3  . NAG O 3 .   ? 93.834  136.352 87.563  1.00 100.84 ? 1   NAG J C3  1 
HETATM 14264 C C4  . NAG O 3 .   ? 94.265  137.214 88.742  1.00 103.69 ? 1   NAG J C4  1 
HETATM 14265 C C5  . NAG O 3 .   ? 95.727  137.620 88.580  1.00 97.74  ? 1   NAG J C5  1 
HETATM 14266 C C6  . NAG O 3 .   ? 96.264  138.387 89.767  1.00 99.94  ? 1   NAG J C6  1 
HETATM 14267 C C7  . NAG O 3 .   ? 94.179  133.045 86.337  1.00 92.66  ? 1   NAG J C7  1 
HETATM 14268 C C8  . NAG O 3 .   ? 93.824  132.365 85.047  1.00 90.74  ? 1   NAG J C8  1 
HETATM 14269 N N2  . NAG O 3 .   ? 94.420  134.358 86.261  1.00 92.24  ? 1   NAG J N2  1 
HETATM 14270 O O3  . NAG O 3 .   ? 92.504  135.881 87.759  1.00 102.13 ? 1   NAG J O3  1 
HETATM 14271 O O4  . NAG O 3 .   ? 93.459  138.386 88.812  1.00 111.36 ? 1   NAG J O4  1 
HETATM 14272 O O5  . NAG O 3 .   ? 96.544  136.447 88.450  1.00 91.03  ? 1   NAG J O5  1 
HETATM 14273 O O6  . NAG O 3 .   ? 96.216  137.604 90.950  1.00 101.76 ? 1   NAG J O6  1 
HETATM 14274 O O7  . NAG O 3 .   ? 94.243  132.432 87.399  1.00 93.98  ? 1   NAG J O7  1 
HETATM 14275 C C1  . NAG O 3 .   ? 92.642  138.338 90.001  1.00 111.74 ? 2   NAG J C1  1 
HETATM 14276 C C2  . NAG O 3 .   ? 92.487  139.759 90.538  1.00 112.91 ? 2   NAG J C2  1 
HETATM 14277 C C3  . NAG O 3 .   ? 91.611  139.752 91.787  1.00 113.50 ? 2   NAG J C3  1 
HETATM 14278 C C4  . NAG O 3 .   ? 90.277  139.090 91.471  1.00 116.56 ? 2   NAG J C4  1 
HETATM 14279 C C5  . NAG O 3 .   ? 90.504  137.700 90.882  1.00 116.33 ? 2   NAG J C5  1 
HETATM 14280 C C6  . NAG O 3 .   ? 89.221  137.040 90.429  1.00 118.29 ? 2   NAG J C6  1 
HETATM 14281 C C7  . NAG O 3 .   ? 94.290  141.361 90.092  1.00 111.93 ? 2   NAG J C7  1 
HETATM 14282 C C8  . NAG O 3 .   ? 95.635  141.869 90.523  1.00 98.33  ? 2   NAG J C8  1 
HETATM 14283 N N2  . NAG O 3 .   ? 93.780  140.360 90.820  1.00 115.82 ? 2   NAG J N2  1 
HETATM 14284 O O3  . NAG O 3 .   ? 91.405  141.089 92.230  1.00 112.14 ? 2   NAG J O3  1 
HETATM 14285 O O4  . NAG O 3 .   ? 89.496  138.973 92.656  1.00 113.33 ? 2   NAG J O4  1 
HETATM 14286 O O5  . NAG O 3 .   ? 91.352  137.789 89.724  1.00 114.18 ? 2   NAG J O5  1 
HETATM 14287 O O6  . NAG O 3 .   ? 89.467  135.779 89.823  1.00 113.68 ? 2   NAG J O6  1 
HETATM 14288 O O7  . NAG O 3 .   ? 93.695  141.833 89.128  1.00 111.07 ? 2   NAG J O7  1 
HETATM 14289 C C1  . NAG P 4 .   ? 114.002 153.109 68.772  1.00 140.83 ? 501 NAG A C1  1 
HETATM 14290 C C2  . NAG P 4 .   ? 113.053 153.491 67.637  1.00 142.04 ? 501 NAG A C2  1 
HETATM 14291 C C3  . NAG P 4 .   ? 113.117 152.450 66.523  1.00 142.34 ? 501 NAG A C3  1 
HETATM 14292 C C4  . NAG P 4 .   ? 114.558 152.270 66.066  1.00 142.92 ? 501 NAG A C4  1 
HETATM 14293 C C5  . NAG P 4 .   ? 115.437 151.918 67.262  1.00 141.96 ? 501 NAG A C5  1 
HETATM 14294 C C6  . NAG P 4 .   ? 116.904 151.819 66.910  1.00 138.22 ? 501 NAG A C6  1 
HETATM 14295 C C7  . NAG P 4 .   ? 111.045 154.804 68.157  1.00 139.09 ? 501 NAG A C7  1 
HETATM 14296 C C8  . NAG P 4 .   ? 109.643 154.768 68.693  1.00 135.93 ? 501 NAG A C8  1 
HETATM 14297 N N2  . NAG P 4 .   ? 111.691 153.633 68.127  1.00 141.49 ? 501 NAG A N2  1 
HETATM 14298 O O3  . NAG P 4 .   ? 112.306 152.870 65.431  1.00 142.78 ? 501 NAG A O3  1 
HETATM 14299 O O4  . NAG P 4 .   ? 114.639 151.226 65.101  1.00 141.44 ? 501 NAG A O4  1 
HETATM 14300 O O5  . NAG P 4 .   ? 115.323 152.947 68.258  1.00 139.99 ? 501 NAG A O5  1 
HETATM 14301 O O6  . NAG P 4 .   ? 117.410 153.065 66.452  1.00 138.30 ? 501 NAG A O6  1 
HETATM 14302 O O7  . NAG P 4 .   ? 111.567 155.845 67.769  1.00 136.81 ? 501 NAG A O7  1 
HETATM 14303 N N   . HSM Q 5 .   ? 149.639 146.782 100.638 1.00 70.84  ? 502 HSM A N   1 
HETATM 14304 C CA  . HSM Q 5 .   ? 149.675 146.548 99.172  1.00 71.70  ? 502 HSM A CA  1 
HETATM 14305 C CB  . HSM Q 5 .   ? 149.718 145.070 98.853  1.00 69.54  ? 502 HSM A CB  1 
HETATM 14306 C CG  . HSM Q 5 .   ? 150.967 144.398 99.327  1.00 85.87  ? 502 HSM A CG  1 
HETATM 14307 N ND1 . HSM Q 5 .   ? 151.916 143.911 98.442  1.00 86.59  ? 502 HSM A ND1 1 
HETATM 14308 C CD2 . HSM Q 5 .   ? 151.379 144.153 100.602 1.00 86.11  ? 502 HSM A CD2 1 
HETATM 14309 C CE1 . HSM Q 5 .   ? 152.866 143.391 99.204  1.00 91.21  ? 502 HSM A CE1 1 
HETATM 14310 N NE2 . HSM Q 5 .   ? 152.584 143.514 100.507 1.00 92.11  ? 502 HSM A NE2 1 
HETATM 14311 N N   . HSM R 5 .   ? 120.589 153.747 100.031 1.00 67.30  ? 503 HSM A N   1 
HETATM 14312 C CA  . HSM R 5 .   ? 121.119 154.446 98.834  1.00 65.34  ? 503 HSM A CA  1 
HETATM 14313 C CB  . HSM R 5 .   ? 122.630 154.410 98.800  1.00 63.62  ? 503 HSM A CB  1 
HETATM 14314 C CG  . HSM R 5 .   ? 123.273 155.256 99.853  1.00 67.18  ? 503 HSM A CG  1 
HETATM 14315 N ND1 . HSM R 5 .   ? 124.502 155.865 99.653  1.00 72.66  ? 503 HSM A ND1 1 
HETATM 14316 C CD2 . HSM R 5 .   ? 122.821 155.565 101.101 1.00 65.17  ? 503 HSM A CD2 1 
HETATM 14317 C CE1 . HSM R 5 .   ? 124.754 156.518 100.777 1.00 70.41  ? 503 HSM A CE1 1 
HETATM 14318 N NE2 . HSM R 5 .   ? 123.771 156.365 101.673 1.00 66.35  ? 503 HSM A NE2 1 
HETATM 14319 N N   . HSM S 5 .   ? 151.239 116.861 99.406  1.00 58.38  ? 501 HSM B N   1 
HETATM 14320 C CA  . HSM S 5 .   ? 151.182 116.059 98.158  1.00 57.97  ? 501 HSM B CA  1 
HETATM 14321 C CB  . HSM S 5 .   ? 150.043 115.064 98.194  1.00 65.74  ? 501 HSM B CB  1 
HETATM 14322 C CG  . HSM S 5 .   ? 150.240 113.968 99.194  1.00 83.17  ? 501 HSM B CG  1 
HETATM 14323 N ND1 . HSM S 5 .   ? 149.445 112.833 99.200  1.00 88.48  ? 501 HSM B ND1 1 
HETATM 14324 C CD2 . HSM S 5 .   ? 151.156 113.878 100.199 1.00 83.02  ? 501 HSM B CD2 1 
HETATM 14325 C CE1 . HSM S 5 .   ? 149.901 112.096 100.201 1.00 81.72  ? 501 HSM B CE1 1 
HETATM 14326 N NE2 . HSM S 5 .   ? 150.927 112.684 100.828 1.00 82.39  ? 501 HSM B NE2 1 
HETATM 14327 C C1  . NAG T 4 .   ? 146.917 151.323 68.242  1.00 134.89 ? 502 NAG B C1  1 
HETATM 14328 C C2  . NAG T 4 .   ? 147.026 152.108 66.936  1.00 140.14 ? 502 NAG B C2  1 
HETATM 14329 C C3  . NAG T 4 .   ? 146.047 151.551 65.906  1.00 141.32 ? 502 NAG B C3  1 
HETATM 14330 C C4  . NAG T 4 .   ? 146.275 150.056 65.731  1.00 138.64 ? 502 NAG B C4  1 
HETATM 14331 C C5  . NAG T 4 .   ? 146.190 149.356 67.084  1.00 133.56 ? 502 NAG B C5  1 
HETATM 14332 C C6  . NAG T 4 .   ? 146.504 147.879 67.007  1.00 124.80 ? 502 NAG B C6  1 
HETATM 14333 C C7  . NAG T 4 .   ? 147.548 154.488 66.635  1.00 135.49 ? 502 NAG B C7  1 
HETATM 14334 C C8  . NAG T 4 .   ? 147.158 155.897 66.974  1.00 122.85 ? 502 NAG B C8  1 
HETATM 14335 N N2  . NAG T 4 .   ? 146.784 153.524 67.162  1.00 139.23 ? 502 NAG B N2  1 
HETATM 14336 O O3  . NAG T 4 .   ? 146.230 152.222 64.663  1.00 145.59 ? 502 NAG B O3  1 
HETATM 14337 O O4  . NAG T 4 .   ? 145.290 149.509 64.860  1.00 135.03 ? 502 NAG B O4  1 
HETATM 14338 O O5  . NAG T 4 .   ? 147.144 149.936 67.988  1.00 134.66 ? 502 NAG B O5  1 
HETATM 14339 O O6  . NAG T 4 .   ? 147.832 147.655 66.553  1.00 124.86 ? 502 NAG B O6  1 
HETATM 14340 O O7  . NAG T 4 .   ? 148.510 154.236 65.915  1.00 138.18 ? 502 NAG B O7  1 
HETATM 14341 C C1  . NAG U 4 .   ? 154.423 120.547 67.734  1.00 143.20 ? 501 NAG C C1  1 
HETATM 14342 C C2  . NAG U 4 .   ? 155.122 120.441 66.380  1.00 142.59 ? 501 NAG C C2  1 
HETATM 14343 C C3  . NAG U 4 .   ? 154.305 121.158 65.309  1.00 139.04 ? 501 NAG C C3  1 
HETATM 14344 C C4  . NAG U 4 .   ? 152.883 120.615 65.294  1.00 138.92 ? 501 NAG C C4  1 
HETATM 14345 C C5  . NAG U 4 .   ? 152.272 120.722 66.688  1.00 139.53 ? 501 NAG C C5  1 
HETATM 14346 C C6  . NAG U 4 .   ? 150.895 120.106 66.781  1.00 133.99 ? 501 NAG C C6  1 
HETATM 14347 C C7  . NAG U 4 .   ? 157.542 120.239 66.734  1.00 141.20 ? 501 NAG C C7  1 
HETATM 14348 C C8  . NAG U 4 .   ? 158.858 120.962 66.757  1.00 129.49 ? 501 NAG C C8  1 
HETATM 14349 N N2  . NAG U 4 .   ? 156.469 120.984 66.446  1.00 143.31 ? 501 NAG C N2  1 
HETATM 14350 O O3  . NAG U 4 .   ? 154.914 120.966 64.037  1.00 143.36 ? 501 NAG C O3  1 
HETATM 14351 O O4  . NAG U 4 .   ? 152.089 121.355 64.372  1.00 138.12 ? 501 NAG C O4  1 
HETATM 14352 O O5  . NAG U 4 .   ? 153.098 120.024 67.632  1.00 142.46 ? 501 NAG C O5  1 
HETATM 14353 O O6  . NAG U 4 .   ? 150.934 118.708 66.530  1.00 131.28 ? 501 NAG C O6  1 
HETATM 14354 O O7  . NAG U 4 .   ? 157.457 119.037 66.967  1.00 143.31 ? 501 NAG C O7  1 
HETATM 14355 N N   . HSM V 5 .   ? 123.230 105.941 99.793  1.00 60.28  ? 501 HSM D N   1 
HETATM 14356 C CA  . HSM V 5 .   ? 122.374 105.538 98.648  1.00 64.12  ? 501 HSM D CA  1 
HETATM 14357 C CB  . HSM V 5 .   ? 121.066 106.296 98.646  1.00 70.99  ? 501 HSM D CB  1 
HETATM 14358 C CG  . HSM V 5 .   ? 120.151 105.914 99.766  1.00 90.07  ? 501 HSM D CG  1 
HETATM 14359 N ND1 . HSM V 5 .   ? 118.797 105.700 99.562  1.00 91.78  ? 501 HSM D ND1 1 
HETATM 14360 C CD2 . HSM V 5 .   ? 120.439 105.725 101.084 1.00 89.04  ? 501 HSM D CD2 1 
HETATM 14361 C CE1 . HSM V 5 .   ? 118.311 105.390 100.755 1.00 90.94  ? 501 HSM D CE1 1 
HETATM 14362 N NE2 . HSM V 5 .   ? 119.262 105.393 101.697 1.00 90.79  ? 501 HSM D NE2 1 
HETATM 14363 C C1  . NAG W 4 .   ? 126.933 103.199 68.696  1.00 137.37 ? 502 NAG D C1  1 
HETATM 14364 C C2  . NAG W 4 .   ? 127.643 102.465 67.559  1.00 140.77 ? 502 NAG D C2  1 
HETATM 14365 C C3  . NAG W 4 .   ? 128.169 103.469 66.537  1.00 140.80 ? 502 NAG D C3  1 
HETATM 14366 C C4  . NAG W 4 .   ? 127.033 104.365 66.062  1.00 142.17 ? 502 NAG D C4  1 
HETATM 14367 C C5  . NAG W 4 .   ? 126.347 105.019 67.258  1.00 137.67 ? 502 NAG D C5  1 
HETATM 14368 C C6  . NAG W 4 .   ? 125.139 105.841 66.870  1.00 134.13 ? 502 NAG D C6  1 
HETATM 14369 C C7  . NAG W 4 .   ? 129.032 100.442 67.558  1.00 139.63 ? 502 NAG D C7  1 
HETATM 14370 C C8  . NAG W 4 .   ? 130.181 99.725  68.205  1.00 132.90 ? 502 NAG D C8  1 
HETATM 14371 N N2  . NAG W 4 .   ? 128.724 101.639 68.071  1.00 141.35 ? 502 NAG D N2  1 
HETATM 14372 O O3  . NAG W 4 .   ? 128.741 102.773 65.435  1.00 139.47 ? 502 NAG D O3  1 
HETATM 14373 O O4  . NAG W 4 .   ? 127.538 105.381 65.200  1.00 143.16 ? 502 NAG D O4  1 
HETATM 14374 O O5  . NAG W 4 .   ? 125.881 104.004 68.163  1.00 138.55 ? 502 NAG D O5  1 
HETATM 14375 O O6  . NAG W 4 .   ? 124.152 105.041 66.234  1.00 132.18 ? 502 NAG D O6  1 
HETATM 14376 O O7  . NAG W 4 .   ? 128.410 99.959  66.616  1.00 139.39 ? 502 NAG D O7  1 
HETATM 14377 C C1  . NAG X 4 .   ? 101.987 123.400 68.869  1.00 134.98 ? 501 NAG E C1  1 
HETATM 14378 C C2  . NAG X 4 .   ? 101.094 122.968 67.707  1.00 136.04 ? 501 NAG E C2  1 
HETATM 14379 C C3  . NAG X 4 .   ? 101.932 122.741 66.453  1.00 134.15 ? 501 NAG E C3  1 
HETATM 14380 C C4  . NAG X 4 .   ? 102.749 123.988 66.147  1.00 135.75 ? 501 NAG E C4  1 
HETATM 14381 C C5  . NAG X 4 .   ? 103.587 124.367 67.364  1.00 133.76 ? 501 NAG E C5  1 
HETATM 14382 C C6  . NAG X 4 .   ? 104.356 125.653 67.173  1.00 128.85 ? 501 NAG E C6  1 
HETATM 14383 C C7  . NAG X 4 .   ? 99.016  121.754 68.182  1.00 131.17 ? 501 NAG E C7  1 
HETATM 14384 C C8  . NAG X 4 .   ? 98.405  120.430 68.538  1.00 124.35 ? 501 NAG E C8  1 
HETATM 14385 N N2  . NAG X 4 .   ? 100.346 121.769 68.048  1.00 131.73 ? 501 NAG E N2  1 
HETATM 14386 O O3  . NAG X 4 .   ? 101.075 122.438 65.357  1.00 129.35 ? 501 NAG E O3  1 
HETATM 14387 O O4  . NAG X 4 .   ? 103.608 123.752 65.036  1.00 132.03 ? 501 NAG E O4  1 
HETATM 14388 O O5  . NAG X 4 .   ? 102.727 124.565 68.498  1.00 135.28 ? 501 NAG E O5  1 
HETATM 14389 O O6  . NAG X 4 .   ? 103.482 126.752 66.955  1.00 127.51 ? 501 NAG E O6  1 
HETATM 14390 O O7  . NAG X 4 .   ? 98.334  122.763 68.023  1.00 134.56 ? 501 NAG E O7  1 
# 
