data_9FDY
# 
_entry.id   9FDY 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FDY         pdb_00009fdy 10.2210/pdb9fdy/pdb 
WWPDB D_1292138665 ?            ?                   
EMDB  EMD-50333    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-12 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FDY 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Betaglycan Orphan Domain (ratBGo) in complex with TGF-b1 and extracellular domain of TGFBRII' 
_pdbx_database_related.db_id          EMD-50333 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              Caroline.Hill@crick.ac.uk 
_pdbx_contact_author.name_first         Caroline 
_pdbx_contact_author.name_last          Hill 
_pdbx_contact_author.name_mi            S 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8632-0480 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wieteska, L.'   1 ? 
'Cherepanov, P.' 2 ? 
'Punch, E.'      3 ? 
'Hinck, A.P.'    4 ? 
'Hill, C.S.'     5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                1778 
_citation.page_last                 1778 
_citation.title                     
'Structures of TGF-beta with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-56796-9 
_citation.pdbx_database_id_PubMed   40011426 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wieteska, L.'       1  0000-0002-5890-6513 
primary 'Taylor, A.B.'       2  0000-0003-3517-6033 
primary 'Punch, E.'          3  ?                   
primary 'Coleman, J.A.'      4  0000-0003-0001-6195 
primary 'Conway, I.O.'       5  ?                   
primary 'Lin, Y.F.'          6  0000-0002-2880-4532 
primary 'Byeon, C.H.'        7  0000-0001-9997-7708 
primary 'Hinck, C.S.'        8  ?                   
primary 'Krzysiak, T.'       9  ?                   
primary 'Ishima, R.'         10 ?                   
primary 'Lopez-Casillas, F.' 11 0000-0002-3689-1824 
primary 'Cherepanov, P.'     12 0000-0002-0634-538X 
primary 'Bernard, D.J.'      13 0000-0001-5365-5586 
primary 'Hill, C.S.'         14 0000-0002-8632-0480 
primary 'Hinck, A.P.'        15 0000-0003-3320-8054 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Transforming growth factor beta-1'               12809.812 2 ?         ? Mature ? 
2 polymer man 'Transforming growth factor beta receptor type 3' 38109.473 1 ?         ? ?      ? 
3 polymer man 'TGF-beta receptor type-2'                        12926.812 2 2.7.11.30 ? ?      ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 TGF-beta-1                                                                                                              
2 'TGF-beta receptor type 3,TGFR-3,Betaglycan,Transforming growth factor beta receptor III,TGF-beta receptor type III'    
3 'TGFR-2,TGF-beta type II receptor,Transforming growth factor-beta receptor type II,TGF-beta receptor type II,TbetaR-II' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVP
QALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
;
;ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVP
QALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
;
A,B ? 
2 'polypeptide(L)' no no 
;GSPCELSPINASHPVQALMESFTVLSGCASRGTTGLPREVHVLNLRSTDQGPGQRQREVTLHLNPIASVHTHHKPIVFLL
NSPQPLVWHLKTERLAAGVPRLFLVSEGSVVQFPSGNFSLTAETEERNFPQENEHLLRWAQKEYGAVTSFTELKIARNIY
IKVGEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLPSQPHEKEVHIIELITPSSNPYSAFQVDIIVDIRPAQEDPE
VVKNLVLILKCKKSVNWVIKSFDVKGNLKVIAPNSIGFGKESERSMTMTKLVRDDIPSTQENLMKWALDNGYRPVTSYTM
APVANRFHLRLENHHHHHH
;
;GSPCELSPINASHPVQALMESFTVLSGCASRGTTGLPREVHVLNLRSTDQGPGQRQREVTLHLNPIASVHTHHKPIVFLL
NSPQPLVWHLKTERLAAGVPRLFLVSEGSVVQFPSGNFSLTAETEERNFPQENEHLLRWAQKEYGAVTSFTELKIARNIY
IKVGEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLPSQPHEKEVHIIELITPSSNPYSAFQVDIIVDIRPAQEDPE
VVKNLVLILKCKKSVNWVIKSFDVKGNLKVIAPNSIGFGKESERSMTMTKLVRDDIPSTQENLMKWALDNGYRPVTSYTM
APVANRFHLRLENHHHHHH
;
C   ? 
3 'polypeptide(L)' no no 
;MNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPK
CIMKEKKKPGETFFMCSCSSDECNDNIIFSEEY
;
;MNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPK
CIMKEKKKPGETFFMCSCSSDECNDNIIFSEEY
;
D,E ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   LEU n 
1 3   ASP n 
1 4   THR n 
1 5   ASN n 
1 6   TYR n 
1 7   CYS n 
1 8   PHE n 
1 9   SER n 
1 10  SER n 
1 11  THR n 
1 12  GLU n 
1 13  LYS n 
1 14  ASN n 
1 15  CYS n 
1 16  CYS n 
1 17  VAL n 
1 18  ARG n 
1 19  GLN n 
1 20  LEU n 
1 21  TYR n 
1 22  ILE n 
1 23  ASP n 
1 24  PHE n 
1 25  ARG n 
1 26  LYS n 
1 27  ASP n 
1 28  LEU n 
1 29  GLY n 
1 30  TRP n 
1 31  LYS n 
1 32  TRP n 
1 33  ILE n 
1 34  HIS n 
1 35  GLU n 
1 36  PRO n 
1 37  LYS n 
1 38  GLY n 
1 39  TYR n 
1 40  HIS n 
1 41  ALA n 
1 42  ASN n 
1 43  PHE n 
1 44  CYS n 
1 45  LEU n 
1 46  GLY n 
1 47  PRO n 
1 48  CYS n 
1 49  PRO n 
1 50  TYR n 
1 51  ILE n 
1 52  TRP n 
1 53  SER n 
1 54  LEU n 
1 55  ASP n 
1 56  THR n 
1 57  GLN n 
1 58  TYR n 
1 59  SER n 
1 60  LYS n 
1 61  VAL n 
1 62  LEU n 
1 63  ALA n 
1 64  LEU n 
1 65  TYR n 
1 66  ASN n 
1 67  GLN n 
1 68  HIS n 
1 69  ASN n 
1 70  PRO n 
1 71  GLY n 
1 72  ALA n 
1 73  SER n 
1 74  ALA n 
1 75  ALA n 
1 76  PRO n 
1 77  CYS n 
1 78  CYS n 
1 79  VAL n 
1 80  PRO n 
1 81  GLN n 
1 82  ALA n 
1 83  LEU n 
1 84  GLU n 
1 85  PRO n 
1 86  LEU n 
1 87  PRO n 
1 88  ILE n 
1 89  VAL n 
1 90  TYR n 
1 91  TYR n 
1 92  VAL n 
1 93  GLY n 
1 94  ARG n 
1 95  LYS n 
1 96  PRO n 
1 97  LYS n 
1 98  VAL n 
1 99  GLU n 
1 100 GLN n 
1 101 LEU n 
1 102 SER n 
1 103 ASN n 
1 104 MET n 
1 105 ILE n 
1 106 VAL n 
1 107 ARG n 
1 108 SER n 
1 109 CYS n 
1 110 LYS n 
1 111 CYS n 
1 112 SER n 
2 1   GLY n 
2 2   SER n 
2 3   PRO n 
2 4   CYS n 
2 5   GLU n 
2 6   LEU n 
2 7   SER n 
2 8   PRO n 
2 9   ILE n 
2 10  ASN n 
2 11  ALA n 
2 12  SER n 
2 13  HIS n 
2 14  PRO n 
2 15  VAL n 
2 16  GLN n 
2 17  ALA n 
2 18  LEU n 
2 19  MET n 
2 20  GLU n 
2 21  SER n 
2 22  PHE n 
2 23  THR n 
2 24  VAL n 
2 25  LEU n 
2 26  SER n 
2 27  GLY n 
2 28  CYS n 
2 29  ALA n 
2 30  SER n 
2 31  ARG n 
2 32  GLY n 
2 33  THR n 
2 34  THR n 
2 35  GLY n 
2 36  LEU n 
2 37  PRO n 
2 38  ARG n 
2 39  GLU n 
2 40  VAL n 
2 41  HIS n 
2 42  VAL n 
2 43  LEU n 
2 44  ASN n 
2 45  LEU n 
2 46  ARG n 
2 47  SER n 
2 48  THR n 
2 49  ASP n 
2 50  GLN n 
2 51  GLY n 
2 52  PRO n 
2 53  GLY n 
2 54  GLN n 
2 55  ARG n 
2 56  GLN n 
2 57  ARG n 
2 58  GLU n 
2 59  VAL n 
2 60  THR n 
2 61  LEU n 
2 62  HIS n 
2 63  LEU n 
2 64  ASN n 
2 65  PRO n 
2 66  ILE n 
2 67  ALA n 
2 68  SER n 
2 69  VAL n 
2 70  HIS n 
2 71  THR n 
2 72  HIS n 
2 73  HIS n 
2 74  LYS n 
2 75  PRO n 
2 76  ILE n 
2 77  VAL n 
2 78  PHE n 
2 79  LEU n 
2 80  LEU n 
2 81  ASN n 
2 82  SER n 
2 83  PRO n 
2 84  GLN n 
2 85  PRO n 
2 86  LEU n 
2 87  VAL n 
2 88  TRP n 
2 89  HIS n 
2 90  LEU n 
2 91  LYS n 
2 92  THR n 
2 93  GLU n 
2 94  ARG n 
2 95  LEU n 
2 96  ALA n 
2 97  ALA n 
2 98  GLY n 
2 99  VAL n 
2 100 PRO n 
2 101 ARG n 
2 102 LEU n 
2 103 PHE n 
2 104 LEU n 
2 105 VAL n 
2 106 SER n 
2 107 GLU n 
2 108 GLY n 
2 109 SER n 
2 110 VAL n 
2 111 VAL n 
2 112 GLN n 
2 113 PHE n 
2 114 PRO n 
2 115 SER n 
2 116 GLY n 
2 117 ASN n 
2 118 PHE n 
2 119 SER n 
2 120 LEU n 
2 121 THR n 
2 122 ALA n 
2 123 GLU n 
2 124 THR n 
2 125 GLU n 
2 126 GLU n 
2 127 ARG n 
2 128 ASN n 
2 129 PHE n 
2 130 PRO n 
2 131 GLN n 
2 132 GLU n 
2 133 ASN n 
2 134 GLU n 
2 135 HIS n 
2 136 LEU n 
2 137 LEU n 
2 138 ARG n 
2 139 TRP n 
2 140 ALA n 
2 141 GLN n 
2 142 LYS n 
2 143 GLU n 
2 144 TYR n 
2 145 GLY n 
2 146 ALA n 
2 147 VAL n 
2 148 THR n 
2 149 SER n 
2 150 PHE n 
2 151 THR n 
2 152 GLU n 
2 153 LEU n 
2 154 LYS n 
2 155 ILE n 
2 156 ALA n 
2 157 ARG n 
2 158 ASN n 
2 159 ILE n 
2 160 TYR n 
2 161 ILE n 
2 162 LYS n 
2 163 VAL n 
2 164 GLY n 
2 165 GLU n 
2 166 ASP n 
2 167 GLN n 
2 168 VAL n 
2 169 PHE n 
2 170 PRO n 
2 171 PRO n 
2 172 THR n 
2 173 CYS n 
2 174 ASN n 
2 175 ILE n 
2 176 GLY n 
2 177 LYS n 
2 178 ASN n 
2 179 PHE n 
2 180 LEU n 
2 181 SER n 
2 182 LEU n 
2 183 ASN n 
2 184 TYR n 
2 185 LEU n 
2 186 ALA n 
2 187 GLU n 
2 188 TYR n 
2 189 LEU n 
2 190 GLN n 
2 191 PRO n 
2 192 LYS n 
2 193 ALA n 
2 194 ALA n 
2 195 GLU n 
2 196 GLY n 
2 197 CYS n 
2 198 VAL n 
2 199 LEU n 
2 200 PRO n 
2 201 SER n 
2 202 GLN n 
2 203 PRO n 
2 204 HIS n 
2 205 GLU n 
2 206 LYS n 
2 207 GLU n 
2 208 VAL n 
2 209 HIS n 
2 210 ILE n 
2 211 ILE n 
2 212 GLU n 
2 213 LEU n 
2 214 ILE n 
2 215 THR n 
2 216 PRO n 
2 217 SER n 
2 218 SER n 
2 219 ASN n 
2 220 PRO n 
2 221 TYR n 
2 222 SER n 
2 223 ALA n 
2 224 PHE n 
2 225 GLN n 
2 226 VAL n 
2 227 ASP n 
2 228 ILE n 
2 229 ILE n 
2 230 VAL n 
2 231 ASP n 
2 232 ILE n 
2 233 ARG n 
2 234 PRO n 
2 235 ALA n 
2 236 GLN n 
2 237 GLU n 
2 238 ASP n 
2 239 PRO n 
2 240 GLU n 
2 241 VAL n 
2 242 VAL n 
2 243 LYS n 
2 244 ASN n 
2 245 LEU n 
2 246 VAL n 
2 247 LEU n 
2 248 ILE n 
2 249 LEU n 
2 250 LYS n 
2 251 CYS n 
2 252 LYS n 
2 253 LYS n 
2 254 SER n 
2 255 VAL n 
2 256 ASN n 
2 257 TRP n 
2 258 VAL n 
2 259 ILE n 
2 260 LYS n 
2 261 SER n 
2 262 PHE n 
2 263 ASP n 
2 264 VAL n 
2 265 LYS n 
2 266 GLY n 
2 267 ASN n 
2 268 LEU n 
2 269 LYS n 
2 270 VAL n 
2 271 ILE n 
2 272 ALA n 
2 273 PRO n 
2 274 ASN n 
2 275 SER n 
2 276 ILE n 
2 277 GLY n 
2 278 PHE n 
2 279 GLY n 
2 280 LYS n 
2 281 GLU n 
2 282 SER n 
2 283 GLU n 
2 284 ARG n 
2 285 SER n 
2 286 MET n 
2 287 THR n 
2 288 MET n 
2 289 THR n 
2 290 LYS n 
2 291 LEU n 
2 292 VAL n 
2 293 ARG n 
2 294 ASP n 
2 295 ASP n 
2 296 ILE n 
2 297 PRO n 
2 298 SER n 
2 299 THR n 
2 300 GLN n 
2 301 GLU n 
2 302 ASN n 
2 303 LEU n 
2 304 MET n 
2 305 LYS n 
2 306 TRP n 
2 307 ALA n 
2 308 LEU n 
2 309 ASP n 
2 310 ASN n 
2 311 GLY n 
2 312 TYR n 
2 313 ARG n 
2 314 PRO n 
2 315 VAL n 
2 316 THR n 
2 317 SER n 
2 318 TYR n 
2 319 THR n 
2 320 MET n 
2 321 ALA n 
2 322 PRO n 
2 323 VAL n 
2 324 ALA n 
2 325 ASN n 
2 326 ARG n 
2 327 PHE n 
2 328 HIS n 
2 329 LEU n 
2 330 ARG n 
2 331 LEU n 
2 332 GLU n 
2 333 ASN n 
2 334 HIS n 
2 335 HIS n 
2 336 HIS n 
2 337 HIS n 
2 338 HIS n 
2 339 HIS n 
3 1   MET n 
3 2   ASN n 
3 3   GLY n 
3 4   ALA n 
3 5   VAL n 
3 6   LYS n 
3 7   PHE n 
3 8   PRO n 
3 9   GLN n 
3 10  LEU n 
3 11  CYS n 
3 12  LYS n 
3 13  PHE n 
3 14  CYS n 
3 15  ASP n 
3 16  VAL n 
3 17  ARG n 
3 18  PHE n 
3 19  SER n 
3 20  THR n 
3 21  CYS n 
3 22  ASP n 
3 23  ASN n 
3 24  GLN n 
3 25  LYS n 
3 26  SER n 
3 27  CYS n 
3 28  MET n 
3 29  SER n 
3 30  ASN n 
3 31  CYS n 
3 32  SER n 
3 33  ILE n 
3 34  THR n 
3 35  SER n 
3 36  ILE n 
3 37  CYS n 
3 38  GLU n 
3 39  LYS n 
3 40  PRO n 
3 41  GLN n 
3 42  GLU n 
3 43  VAL n 
3 44  CYS n 
3 45  VAL n 
3 46  ALA n 
3 47  VAL n 
3 48  TRP n 
3 49  ARG n 
3 50  LYS n 
3 51  ASN n 
3 52  ASP n 
3 53  GLU n 
3 54  ASN n 
3 55  ILE n 
3 56  THR n 
3 57  LEU n 
3 58  GLU n 
3 59  THR n 
3 60  VAL n 
3 61  CYS n 
3 62  HIS n 
3 63  ASP n 
3 64  PRO n 
3 65  LYS n 
3 66  LEU n 
3 67  PRO n 
3 68  TYR n 
3 69  HIS n 
3 70  ASP n 
3 71  PHE n 
3 72  ILE n 
3 73  LEU n 
3 74  GLU n 
3 75  ASP n 
3 76  ALA n 
3 77  ALA n 
3 78  SER n 
3 79  PRO n 
3 80  LYS n 
3 81  CYS n 
3 82  ILE n 
3 83  MET n 
3 84  LYS n 
3 85  GLU n 
3 86  LYS n 
3 87  LYS n 
3 88  LYS n 
3 89  PRO n 
3 90  GLY n 
3 91  GLU n 
3 92  THR n 
3 93  PHE n 
3 94  PHE n 
3 95  MET n 
3 96  CYS n 
3 97  SER n 
3 98  CYS n 
3 99  SER n 
3 100 SER n 
3 101 ASP n 
3 102 GLU n 
3 103 CYS n 
3 104 ASN n 
3 105 ASP n 
3 106 ASN n 
3 107 ILE n 
3 108 ILE n 
3 109 PHE n 
3 110 SER n 
3 111 GLU n 
3 112 GLU n 
3 113 TYR n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 112 human        ? 'TGFB1, TGFB' ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? ? ? ? ? 
'Escherichia coli' 562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 339 'Norway rat' ? Tgfbr3        ? ? ? ? ? ? 'Rattus norvegicus' 10116 ? ? ? ? ? ? ? ? 
'Homo sapiens'     9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 113 human        ? TGFBR2        ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? ? ? ? ? 
'Escherichia coli' 562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   1   ALA ALA A . n 
A 1 2   LEU 2   2   2   LEU LEU A . n 
A 1 3   ASP 3   3   3   ASP ASP A . n 
A 1 4   THR 4   4   4   THR THR A . n 
A 1 5   ASN 5   5   5   ASN ASN A . n 
A 1 6   TYR 6   6   6   TYR TYR A . n 
A 1 7   CYS 7   7   7   CYS CYS A . n 
A 1 8   PHE 8   8   8   PHE PHE A . n 
A 1 9   SER 9   9   9   SER SER A . n 
A 1 10  SER 10  10  10  SER SER A . n 
A 1 11  THR 11  11  11  THR THR A . n 
A 1 12  GLU 12  12  12  GLU GLU A . n 
A 1 13  LYS 13  13  13  LYS LYS A . n 
A 1 14  ASN 14  14  14  ASN ASN A . n 
A 1 15  CYS 15  15  15  CYS CYS A . n 
A 1 16  CYS 16  16  16  CYS CYS A . n 
A 1 17  VAL 17  17  17  VAL VAL A . n 
A 1 18  ARG 18  18  18  ARG ARG A . n 
A 1 19  GLN 19  19  19  GLN GLN A . n 
A 1 20  LEU 20  20  20  LEU LEU A . n 
A 1 21  TYR 21  21  21  TYR TYR A . n 
A 1 22  ILE 22  22  22  ILE ILE A . n 
A 1 23  ASP 23  23  23  ASP ASP A . n 
A 1 24  PHE 24  24  24  PHE PHE A . n 
A 1 25  ARG 25  25  25  ARG ARG A . n 
A 1 26  LYS 26  26  26  LYS LYS A . n 
A 1 27  ASP 27  27  27  ASP ASP A . n 
A 1 28  LEU 28  28  28  LEU LEU A . n 
A 1 29  GLY 29  29  29  GLY GLY A . n 
A 1 30  TRP 30  30  30  TRP TRP A . n 
A 1 31  LYS 31  31  31  LYS LYS A . n 
A 1 32  TRP 32  32  32  TRP TRP A . n 
A 1 33  ILE 33  33  33  ILE ILE A . n 
A 1 34  HIS 34  34  34  HIS HIS A . n 
A 1 35  GLU 35  35  35  GLU GLU A . n 
A 1 36  PRO 36  36  36  PRO PRO A . n 
A 1 37  LYS 37  37  37  LYS LYS A . n 
A 1 38  GLY 38  38  38  GLY GLY A . n 
A 1 39  TYR 39  39  39  TYR TYR A . n 
A 1 40  HIS 40  40  40  HIS HIS A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  ASN 42  42  42  ASN ASN A . n 
A 1 43  PHE 43  43  43  PHE PHE A . n 
A 1 44  CYS 44  44  44  CYS CYS A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  GLY 46  46  46  GLY GLY A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  CYS 48  48  48  CYS CYS A . n 
A 1 49  PRO 49  49  49  PRO PRO A . n 
A 1 50  TYR 50  50  50  TYR TYR A . n 
A 1 51  ILE 51  51  51  ILE ILE A . n 
A 1 52  TRP 52  52  52  TRP TRP A . n 
A 1 53  SER 53  53  53  SER SER A . n 
A 1 54  LEU 54  54  54  LEU LEU A . n 
A 1 55  ASP 55  55  55  ASP ASP A . n 
A 1 56  THR 56  56  56  THR THR A . n 
A 1 57  GLN 57  57  57  GLN GLN A . n 
A 1 58  TYR 58  58  58  TYR TYR A . n 
A 1 59  SER 59  59  59  SER SER A . n 
A 1 60  LYS 60  60  60  LYS LYS A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  LEU 62  62  62  LEU LEU A . n 
A 1 63  ALA 63  63  63  ALA ALA A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  TYR 65  65  65  TYR TYR A . n 
A 1 66  ASN 66  66  66  ASN ASN A . n 
A 1 67  GLN 67  67  67  GLN GLN A . n 
A 1 68  HIS 68  68  68  HIS HIS A . n 
A 1 69  ASN 69  69  69  ASN ASN A . n 
A 1 70  PRO 70  70  70  PRO PRO A . n 
A 1 71  GLY 71  71  71  GLY GLY A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  SER 73  73  73  SER SER A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  ALA 75  75  75  ALA ALA A . n 
A 1 76  PRO 76  76  76  PRO PRO A . n 
A 1 77  CYS 77  77  77  CYS CYS A . n 
A 1 78  CYS 78  78  78  CYS CYS A . n 
A 1 79  VAL 79  79  79  VAL VAL A . n 
A 1 80  PRO 80  80  80  PRO PRO A . n 
A 1 81  GLN 81  81  81  GLN GLN A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  GLU 84  84  84  GLU GLU A . n 
A 1 85  PRO 85  85  85  PRO PRO A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  PRO 87  87  87  PRO PRO A . n 
A 1 88  ILE 88  88  88  ILE ILE A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  TYR 90  90  90  TYR TYR A . n 
A 1 91  TYR 91  91  91  TYR TYR A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  GLY 93  93  93  GLY GLY A . n 
A 1 94  ARG 94  94  94  ARG ARG A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  LYS 97  97  97  LYS LYS A . n 
A 1 98  VAL 98  98  98  VAL VAL A . n 
A 1 99  GLU 99  99  99  GLU GLU A . n 
A 1 100 GLN 100 100 100 GLN GLN A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 SER 102 102 102 SER SER A . n 
A 1 103 ASN 103 103 103 ASN ASN A . n 
A 1 104 MET 104 104 104 MET MET A . n 
A 1 105 ILE 105 105 105 ILE ILE A . n 
A 1 106 VAL 106 106 106 VAL VAL A . n 
A 1 107 ARG 107 107 107 ARG ARG A . n 
A 1 108 SER 108 108 108 SER SER A . n 
A 1 109 CYS 109 109 109 CYS CYS A . n 
A 1 110 LYS 110 110 110 LYS LYS A . n 
A 1 111 CYS 111 111 111 CYS CYS A . n 
A 1 112 SER 112 112 112 SER SER A . n 
B 1 1   ALA 1   1   1   ALA ALA B . n 
B 1 2   LEU 2   2   2   LEU LEU B . n 
B 1 3   ASP 3   3   3   ASP ASP B . n 
B 1 4   THR 4   4   4   THR THR B . n 
B 1 5   ASN 5   5   5   ASN ASN B . n 
B 1 6   TYR 6   6   6   TYR TYR B . n 
B 1 7   CYS 7   7   7   CYS CYS B . n 
B 1 8   PHE 8   8   8   PHE PHE B . n 
B 1 9   SER 9   9   9   SER SER B . n 
B 1 10  SER 10  10  10  SER SER B . n 
B 1 11  THR 11  11  11  THR THR B . n 
B 1 12  GLU 12  12  12  GLU GLU B . n 
B 1 13  LYS 13  13  13  LYS LYS B . n 
B 1 14  ASN 14  14  14  ASN ASN B . n 
B 1 15  CYS 15  15  15  CYS CYS B . n 
B 1 16  CYS 16  16  16  CYS CYS B . n 
B 1 17  VAL 17  17  17  VAL VAL B . n 
B 1 18  ARG 18  18  18  ARG ARG B . n 
B 1 19  GLN 19  19  19  GLN GLN B . n 
B 1 20  LEU 20  20  20  LEU LEU B . n 
B 1 21  TYR 21  21  21  TYR TYR B . n 
B 1 22  ILE 22  22  22  ILE ILE B . n 
B 1 23  ASP 23  23  23  ASP ASP B . n 
B 1 24  PHE 24  24  24  PHE PHE B . n 
B 1 25  ARG 25  25  25  ARG ARG B . n 
B 1 26  LYS 26  26  26  LYS LYS B . n 
B 1 27  ASP 27  27  27  ASP ASP B . n 
B 1 28  LEU 28  28  28  LEU LEU B . n 
B 1 29  GLY 29  29  29  GLY GLY B . n 
B 1 30  TRP 30  30  30  TRP TRP B . n 
B 1 31  LYS 31  31  31  LYS LYS B . n 
B 1 32  TRP 32  32  32  TRP TRP B . n 
B 1 33  ILE 33  33  33  ILE ILE B . n 
B 1 34  HIS 34  34  34  HIS HIS B . n 
B 1 35  GLU 35  35  35  GLU GLU B . n 
B 1 36  PRO 36  36  36  PRO PRO B . n 
B 1 37  LYS 37  37  37  LYS LYS B . n 
B 1 38  GLY 38  38  38  GLY GLY B . n 
B 1 39  TYR 39  39  39  TYR TYR B . n 
B 1 40  HIS 40  40  40  HIS HIS B . n 
B 1 41  ALA 41  41  41  ALA ALA B . n 
B 1 42  ASN 42  42  42  ASN ASN B . n 
B 1 43  PHE 43  43  43  PHE PHE B . n 
B 1 44  CYS 44  44  44  CYS CYS B . n 
B 1 45  LEU 45  45  45  LEU LEU B . n 
B 1 46  GLY 46  46  46  GLY GLY B . n 
B 1 47  PRO 47  47  47  PRO PRO B . n 
B 1 48  CYS 48  48  48  CYS CYS B . n 
B 1 49  PRO 49  49  49  PRO PRO B . n 
B 1 50  TYR 50  50  50  TYR TYR B . n 
B 1 51  ILE 51  51  51  ILE ILE B . n 
B 1 52  TRP 52  52  52  TRP TRP B . n 
B 1 53  SER 53  53  53  SER SER B . n 
B 1 54  LEU 54  54  54  LEU LEU B . n 
B 1 55  ASP 55  55  55  ASP ASP B . n 
B 1 56  THR 56  56  56  THR THR B . n 
B 1 57  GLN 57  57  57  GLN GLN B . n 
B 1 58  TYR 58  58  58  TYR TYR B . n 
B 1 59  SER 59  59  59  SER SER B . n 
B 1 60  LYS 60  60  60  LYS LYS B . n 
B 1 61  VAL 61  61  61  VAL VAL B . n 
B 1 62  LEU 62  62  62  LEU LEU B . n 
B 1 63  ALA 63  63  63  ALA ALA B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  TYR 65  65  65  TYR TYR B . n 
B 1 66  ASN 66  66  66  ASN ASN B . n 
B 1 67  GLN 67  67  67  GLN GLN B . n 
B 1 68  HIS 68  68  68  HIS HIS B . n 
B 1 69  ASN 69  69  69  ASN ASN B . n 
B 1 70  PRO 70  70  70  PRO PRO B . n 
B 1 71  GLY 71  71  71  GLY GLY B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  SER 73  73  73  SER SER B . n 
B 1 74  ALA 74  74  74  ALA ALA B . n 
B 1 75  ALA 75  75  75  ALA ALA B . n 
B 1 76  PRO 76  76  76  PRO PRO B . n 
B 1 77  CYS 77  77  77  CYS CYS B . n 
B 1 78  CYS 78  78  78  CYS CYS B . n 
B 1 79  VAL 79  79  79  VAL VAL B . n 
B 1 80  PRO 80  80  80  PRO PRO B . n 
B 1 81  GLN 81  81  81  GLN GLN B . n 
B 1 82  ALA 82  82  82  ALA ALA B . n 
B 1 83  LEU 83  83  83  LEU LEU B . n 
B 1 84  GLU 84  84  84  GLU GLU B . n 
B 1 85  PRO 85  85  85  PRO PRO B . n 
B 1 86  LEU 86  86  86  LEU LEU B . n 
B 1 87  PRO 87  87  87  PRO PRO B . n 
B 1 88  ILE 88  88  88  ILE ILE B . n 
B 1 89  VAL 89  89  89  VAL VAL B . n 
B 1 90  TYR 90  90  90  TYR TYR B . n 
B 1 91  TYR 91  91  91  TYR TYR B . n 
B 1 92  VAL 92  92  92  VAL VAL B . n 
B 1 93  GLY 93  93  93  GLY GLY B . n 
B 1 94  ARG 94  94  94  ARG ARG B . n 
B 1 95  LYS 95  95  95  LYS LYS B . n 
B 1 96  PRO 96  96  96  PRO PRO B . n 
B 1 97  LYS 97  97  97  LYS LYS B . n 
B 1 98  VAL 98  98  98  VAL VAL B . n 
B 1 99  GLU 99  99  99  GLU GLU B . n 
B 1 100 GLN 100 100 100 GLN GLN B . n 
B 1 101 LEU 101 101 101 LEU LEU B . n 
B 1 102 SER 102 102 102 SER SER B . n 
B 1 103 ASN 103 103 103 ASN ASN B . n 
B 1 104 MET 104 104 104 MET MET B . n 
B 1 105 ILE 105 105 105 ILE ILE B . n 
B 1 106 VAL 106 106 106 VAL VAL B . n 
B 1 107 ARG 107 107 107 ARG ARG B . n 
B 1 108 SER 108 108 108 SER SER B . n 
B 1 109 CYS 109 109 109 CYS CYS B . n 
B 1 110 LYS 110 110 110 LYS LYS B . n 
B 1 111 CYS 111 111 111 CYS CYS B . n 
B 1 112 SER 112 112 112 SER SER B . n 
C 2 1   GLY 1   1   ?   ?   ?   C . n 
C 2 2   SER 2   2   ?   ?   ?   C . n 
C 2 3   PRO 3   3   ?   ?   ?   C . n 
C 2 4   CYS 4   4   4   CYS CYS C . n 
C 2 5   GLU 5   5   5   GLU GLU C . n 
C 2 6   LEU 6   6   6   LEU LEU C . n 
C 2 7   SER 7   7   7   SER SER C . n 
C 2 8   PRO 8   8   8   PRO PRO C . n 
C 2 9   ILE 9   9   9   ILE ILE C . n 
C 2 10  ASN 10  10  10  ASN ASN C . n 
C 2 11  ALA 11  11  11  ALA ALA C . n 
C 2 12  SER 12  12  12  SER SER C . n 
C 2 13  HIS 13  13  13  HIS HIS C . n 
C 2 14  PRO 14  14  14  PRO PRO C . n 
C 2 15  VAL 15  15  15  VAL VAL C . n 
C 2 16  GLN 16  16  16  GLN GLN C . n 
C 2 17  ALA 17  17  17  ALA ALA C . n 
C 2 18  LEU 18  18  18  LEU LEU C . n 
C 2 19  MET 19  19  19  MET MET C . n 
C 2 20  GLU 20  20  20  GLU GLU C . n 
C 2 21  SER 21  21  21  SER SER C . n 
C 2 22  PHE 22  22  22  PHE PHE C . n 
C 2 23  THR 23  23  23  THR THR C . n 
C 2 24  VAL 24  24  24  VAL VAL C . n 
C 2 25  LEU 25  25  25  LEU LEU C . n 
C 2 26  SER 26  26  26  SER SER C . n 
C 2 27  GLY 27  27  27  GLY GLY C . n 
C 2 28  CYS 28  28  28  CYS CYS C . n 
C 2 29  ALA 29  29  29  ALA ALA C . n 
C 2 30  SER 30  30  30  SER SER C . n 
C 2 31  ARG 31  31  31  ARG ARG C . n 
C 2 32  GLY 32  32  32  GLY GLY C . n 
C 2 33  THR 33  33  33  THR THR C . n 
C 2 34  THR 34  34  34  THR THR C . n 
C 2 35  GLY 35  35  35  GLY GLY C . n 
C 2 36  LEU 36  36  36  LEU LEU C . n 
C 2 37  PRO 37  37  37  PRO PRO C . n 
C 2 38  ARG 38  38  38  ARG ARG C . n 
C 2 39  GLU 39  39  39  GLU GLU C . n 
C 2 40  VAL 40  40  40  VAL VAL C . n 
C 2 41  HIS 41  41  41  HIS HIS C . n 
C 2 42  VAL 42  42  42  VAL VAL C . n 
C 2 43  LEU 43  43  43  LEU LEU C . n 
C 2 44  ASN 44  44  44  ASN ASN C . n 
C 2 45  LEU 45  45  45  LEU LEU C . n 
C 2 46  ARG 46  46  46  ARG ARG C . n 
C 2 47  SER 47  47  47  SER SER C . n 
C 2 48  THR 48  48  48  THR THR C . n 
C 2 49  ASP 49  49  49  ASP ASP C . n 
C 2 50  GLN 50  50  50  GLN GLN C . n 
C 2 51  GLY 51  51  51  GLY GLY C . n 
C 2 52  PRO 52  52  52  PRO PRO C . n 
C 2 53  GLY 53  53  53  GLY GLY C . n 
C 2 54  GLN 54  54  54  GLN GLN C . n 
C 2 55  ARG 55  55  55  ARG ARG C . n 
C 2 56  GLN 56  56  56  GLN GLN C . n 
C 2 57  ARG 57  57  57  ARG ARG C . n 
C 2 58  GLU 58  58  58  GLU GLU C . n 
C 2 59  VAL 59  59  59  VAL VAL C . n 
C 2 60  THR 60  60  60  THR THR C . n 
C 2 61  LEU 61  61  61  LEU LEU C . n 
C 2 62  HIS 62  62  62  HIS HIS C . n 
C 2 63  LEU 63  63  63  LEU LEU C . n 
C 2 64  ASN 64  64  64  ASN ASN C . n 
C 2 65  PRO 65  65  65  PRO PRO C . n 
C 2 66  ILE 66  66  66  ILE ILE C . n 
C 2 67  ALA 67  67  67  ALA ALA C . n 
C 2 68  SER 68  68  68  SER SER C . n 
C 2 69  VAL 69  69  69  VAL VAL C . n 
C 2 70  HIS 70  70  70  HIS HIS C . n 
C 2 71  THR 71  71  71  THR THR C . n 
C 2 72  HIS 72  72  72  HIS HIS C . n 
C 2 73  HIS 73  73  73  HIS HIS C . n 
C 2 74  LYS 74  74  74  LYS LYS C . n 
C 2 75  PRO 75  75  75  PRO PRO C . n 
C 2 76  ILE 76  76  76  ILE ILE C . n 
C 2 77  VAL 77  77  77  VAL VAL C . n 
C 2 78  PHE 78  78  78  PHE PHE C . n 
C 2 79  LEU 79  79  79  LEU LEU C . n 
C 2 80  LEU 80  80  80  LEU LEU C . n 
C 2 81  ASN 81  81  81  ASN ASN C . n 
C 2 82  SER 82  82  82  SER SER C . n 
C 2 83  PRO 83  83  83  PRO PRO C . n 
C 2 84  GLN 84  84  84  GLN GLN C . n 
C 2 85  PRO 85  85  85  PRO PRO C . n 
C 2 86  LEU 86  86  86  LEU LEU C . n 
C 2 87  VAL 87  87  87  VAL VAL C . n 
C 2 88  TRP 88  88  88  TRP TRP C . n 
C 2 89  HIS 89  89  89  HIS HIS C . n 
C 2 90  LEU 90  90  90  LEU LEU C . n 
C 2 91  LYS 91  91  91  LYS LYS C . n 
C 2 92  THR 92  92  92  THR THR C . n 
C 2 93  GLU 93  93  93  GLU GLU C . n 
C 2 94  ARG 94  94  94  ARG ARG C . n 
C 2 95  LEU 95  95  95  LEU LEU C . n 
C 2 96  ALA 96  96  96  ALA ALA C . n 
C 2 97  ALA 97  97  97  ALA ALA C . n 
C 2 98  GLY 98  98  98  GLY GLY C . n 
C 2 99  VAL 99  99  99  VAL VAL C . n 
C 2 100 PRO 100 100 100 PRO PRO C . n 
C 2 101 ARG 101 101 101 ARG ARG C . n 
C 2 102 LEU 102 102 102 LEU LEU C . n 
C 2 103 PHE 103 103 103 PHE PHE C . n 
C 2 104 LEU 104 104 104 LEU LEU C . n 
C 2 105 VAL 105 105 105 VAL VAL C . n 
C 2 106 SER 106 106 106 SER SER C . n 
C 2 107 GLU 107 107 107 GLU GLU C . n 
C 2 108 GLY 108 108 108 GLY GLY C . n 
C 2 109 SER 109 109 109 SER SER C . n 
C 2 110 VAL 110 110 110 VAL VAL C . n 
C 2 111 VAL 111 111 111 VAL VAL C . n 
C 2 112 GLN 112 112 112 GLN GLN C . n 
C 2 113 PHE 113 113 113 PHE PHE C . n 
C 2 114 PRO 114 114 114 PRO PRO C . n 
C 2 115 SER 115 115 115 SER SER C . n 
C 2 116 GLY 116 116 116 GLY GLY C . n 
C 2 117 ASN 117 117 117 ASN ASN C . n 
C 2 118 PHE 118 118 118 PHE PHE C . n 
C 2 119 SER 119 119 119 SER SER C . n 
C 2 120 LEU 120 120 120 LEU LEU C . n 
C 2 121 THR 121 121 121 THR THR C . n 
C 2 122 ALA 122 122 122 ALA ALA C . n 
C 2 123 GLU 123 123 123 GLU GLU C . n 
C 2 124 THR 124 124 124 THR THR C . n 
C 2 125 GLU 125 125 125 GLU GLU C . n 
C 2 126 GLU 126 126 126 GLU GLU C . n 
C 2 127 ARG 127 127 127 ARG ARG C . n 
C 2 128 ASN 128 128 128 ASN ASN C . n 
C 2 129 PHE 129 129 129 PHE PHE C . n 
C 2 130 PRO 130 130 130 PRO PRO C . n 
C 2 131 GLN 131 131 131 GLN GLN C . n 
C 2 132 GLU 132 132 132 GLU GLU C . n 
C 2 133 ASN 133 133 133 ASN ASN C . n 
C 2 134 GLU 134 134 134 GLU GLU C . n 
C 2 135 HIS 135 135 135 HIS HIS C . n 
C 2 136 LEU 136 136 136 LEU LEU C . n 
C 2 137 LEU 137 137 137 LEU LEU C . n 
C 2 138 ARG 138 138 138 ARG ARG C . n 
C 2 139 TRP 139 139 139 TRP TRP C . n 
C 2 140 ALA 140 140 140 ALA ALA C . n 
C 2 141 GLN 141 141 141 GLN GLN C . n 
C 2 142 LYS 142 142 142 LYS LYS C . n 
C 2 143 GLU 143 143 143 GLU GLU C . n 
C 2 144 TYR 144 144 144 TYR TYR C . n 
C 2 145 GLY 145 145 145 GLY GLY C . n 
C 2 146 ALA 146 146 146 ALA ALA C . n 
C 2 147 VAL 147 147 147 VAL VAL C . n 
C 2 148 THR 148 148 148 THR THR C . n 
C 2 149 SER 149 149 149 SER SER C . n 
C 2 150 PHE 150 150 150 PHE PHE C . n 
C 2 151 THR 151 151 151 THR THR C . n 
C 2 152 GLU 152 152 152 GLU GLU C . n 
C 2 153 LEU 153 153 153 LEU LEU C . n 
C 2 154 LYS 154 154 154 LYS LYS C . n 
C 2 155 ILE 155 155 155 ILE ILE C . n 
C 2 156 ALA 156 156 156 ALA ALA C . n 
C 2 157 ARG 157 157 157 ARG ARG C . n 
C 2 158 ASN 158 158 158 ASN ASN C . n 
C 2 159 ILE 159 159 159 ILE ILE C . n 
C 2 160 TYR 160 160 160 TYR TYR C . n 
C 2 161 ILE 161 161 161 ILE ILE C . n 
C 2 162 LYS 162 162 162 LYS LYS C . n 
C 2 163 VAL 163 163 163 VAL VAL C . n 
C 2 164 GLY 164 164 164 GLY GLY C . n 
C 2 165 GLU 165 165 165 GLU GLU C . n 
C 2 166 ASP 166 166 166 ASP ASP C . n 
C 2 167 GLN 167 167 167 GLN GLN C . n 
C 2 168 VAL 168 168 168 VAL VAL C . n 
C 2 169 PHE 169 169 169 PHE PHE C . n 
C 2 170 PRO 170 170 170 PRO PRO C . n 
C 2 171 PRO 171 171 171 PRO PRO C . n 
C 2 172 THR 172 172 172 THR THR C . n 
C 2 173 CYS 173 173 173 CYS CYS C . n 
C 2 174 ASN 174 174 174 ASN ASN C . n 
C 2 175 ILE 175 175 175 ILE ILE C . n 
C 2 176 GLY 176 176 176 GLY GLY C . n 
C 2 177 LYS 177 177 177 LYS LYS C . n 
C 2 178 ASN 178 178 178 ASN ASN C . n 
C 2 179 PHE 179 179 179 PHE PHE C . n 
C 2 180 LEU 180 180 180 LEU LEU C . n 
C 2 181 SER 181 181 181 SER SER C . n 
C 2 182 LEU 182 182 182 LEU LEU C . n 
C 2 183 ASN 183 183 183 ASN ASN C . n 
C 2 184 TYR 184 184 184 TYR TYR C . n 
C 2 185 LEU 185 185 185 LEU LEU C . n 
C 2 186 ALA 186 186 186 ALA ALA C . n 
C 2 187 GLU 187 187 187 GLU GLU C . n 
C 2 188 TYR 188 188 188 TYR TYR C . n 
C 2 189 LEU 189 189 189 LEU LEU C . n 
C 2 190 GLN 190 190 190 GLN GLN C . n 
C 2 191 PRO 191 191 191 PRO PRO C . n 
C 2 192 LYS 192 192 192 LYS LYS C . n 
C 2 193 ALA 193 193 193 ALA ALA C . n 
C 2 194 ALA 194 194 194 ALA ALA C . n 
C 2 195 GLU 195 195 195 GLU GLU C . n 
C 2 196 GLY 196 196 196 GLY GLY C . n 
C 2 197 CYS 197 197 197 CYS CYS C . n 
C 2 198 VAL 198 198 198 VAL VAL C . n 
C 2 199 LEU 199 199 199 LEU LEU C . n 
C 2 200 PRO 200 200 200 PRO PRO C . n 
C 2 201 SER 201 201 201 SER SER C . n 
C 2 202 GLN 202 202 202 GLN GLN C . n 
C 2 203 PRO 203 203 203 PRO PRO C . n 
C 2 204 HIS 204 204 204 HIS HIS C . n 
C 2 205 GLU 205 205 205 GLU GLU C . n 
C 2 206 LYS 206 206 206 LYS LYS C . n 
C 2 207 GLU 207 207 207 GLU GLU C . n 
C 2 208 VAL 208 208 208 VAL VAL C . n 
C 2 209 HIS 209 209 209 HIS HIS C . n 
C 2 210 ILE 210 210 210 ILE ILE C . n 
C 2 211 ILE 211 211 211 ILE ILE C . n 
C 2 212 GLU 212 212 212 GLU GLU C . n 
C 2 213 LEU 213 213 213 LEU LEU C . n 
C 2 214 ILE 214 214 214 ILE ILE C . n 
C 2 215 THR 215 215 215 THR THR C . n 
C 2 216 PRO 216 216 216 PRO PRO C . n 
C 2 217 SER 217 217 217 SER SER C . n 
C 2 218 SER 218 218 218 SER SER C . n 
C 2 219 ASN 219 219 219 ASN ASN C . n 
C 2 220 PRO 220 220 220 PRO PRO C . n 
C 2 221 TYR 221 221 221 TYR TYR C . n 
C 2 222 SER 222 222 222 SER SER C . n 
C 2 223 ALA 223 223 223 ALA ALA C . n 
C 2 224 PHE 224 224 224 PHE PHE C . n 
C 2 225 GLN 225 225 225 GLN GLN C . n 
C 2 226 VAL 226 226 226 VAL VAL C . n 
C 2 227 ASP 227 227 227 ASP ASP C . n 
C 2 228 ILE 228 228 228 ILE ILE C . n 
C 2 229 ILE 229 229 229 ILE ILE C . n 
C 2 230 VAL 230 230 230 VAL VAL C . n 
C 2 231 ASP 231 231 231 ASP ASP C . n 
C 2 232 ILE 232 232 232 ILE ILE C . n 
C 2 233 ARG 233 233 233 ARG ARG C . n 
C 2 234 PRO 234 234 234 PRO PRO C . n 
C 2 235 ALA 235 235 235 ALA ALA C . n 
C 2 236 GLN 236 236 236 GLN GLN C . n 
C 2 237 GLU 237 237 237 GLU GLU C . n 
C 2 238 ASP 238 238 238 ASP ASP C . n 
C 2 239 PRO 239 239 239 PRO PRO C . n 
C 2 240 GLU 240 240 240 GLU GLU C . n 
C 2 241 VAL 241 241 241 VAL VAL C . n 
C 2 242 VAL 242 242 242 VAL VAL C . n 
C 2 243 LYS 243 243 243 LYS LYS C . n 
C 2 244 ASN 244 244 244 ASN ASN C . n 
C 2 245 LEU 245 245 245 LEU LEU C . n 
C 2 246 VAL 246 246 246 VAL VAL C . n 
C 2 247 LEU 247 247 247 LEU LEU C . n 
C 2 248 ILE 248 248 248 ILE ILE C . n 
C 2 249 LEU 249 249 249 LEU LEU C . n 
C 2 250 LYS 250 250 250 LYS LYS C . n 
C 2 251 CYS 251 251 251 CYS CYS C . n 
C 2 252 LYS 252 252 252 LYS LYS C . n 
C 2 253 LYS 253 253 253 LYS LYS C . n 
C 2 254 SER 254 254 254 SER SER C . n 
C 2 255 VAL 255 255 255 VAL VAL C . n 
C 2 256 ASN 256 256 256 ASN ASN C . n 
C 2 257 TRP 257 257 257 TRP TRP C . n 
C 2 258 VAL 258 258 258 VAL VAL C . n 
C 2 259 ILE 259 259 259 ILE ILE C . n 
C 2 260 LYS 260 260 260 LYS LYS C . n 
C 2 261 SER 261 261 261 SER SER C . n 
C 2 262 PHE 262 262 262 PHE PHE C . n 
C 2 263 ASP 263 263 263 ASP ASP C . n 
C 2 264 VAL 264 264 264 VAL VAL C . n 
C 2 265 LYS 265 265 265 LYS LYS C . n 
C 2 266 GLY 266 266 266 GLY GLY C . n 
C 2 267 ASN 267 267 267 ASN ASN C . n 
C 2 268 LEU 268 268 268 LEU LEU C . n 
C 2 269 LYS 269 269 269 LYS LYS C . n 
C 2 270 VAL 270 270 270 VAL VAL C . n 
C 2 271 ILE 271 271 271 ILE ILE C . n 
C 2 272 ALA 272 272 272 ALA ALA C . n 
C 2 273 PRO 273 273 273 PRO PRO C . n 
C 2 274 ASN 274 274 274 ASN ASN C . n 
C 2 275 SER 275 275 275 SER SER C . n 
C 2 276 ILE 276 276 276 ILE ILE C . n 
C 2 277 GLY 277 277 277 GLY GLY C . n 
C 2 278 PHE 278 278 278 PHE PHE C . n 
C 2 279 GLY 279 279 279 GLY GLY C . n 
C 2 280 LYS 280 280 280 LYS LYS C . n 
C 2 281 GLU 281 281 281 GLU GLU C . n 
C 2 282 SER 282 282 282 SER SER C . n 
C 2 283 GLU 283 283 283 GLU GLU C . n 
C 2 284 ARG 284 284 284 ARG ARG C . n 
C 2 285 SER 285 285 285 SER SER C . n 
C 2 286 MET 286 286 286 MET MET C . n 
C 2 287 THR 287 287 287 THR THR C . n 
C 2 288 MET 288 288 288 MET MET C . n 
C 2 289 THR 289 289 289 THR THR C . n 
C 2 290 LYS 290 290 290 LYS LYS C . n 
C 2 291 LEU 291 291 291 LEU LEU C . n 
C 2 292 VAL 292 292 292 VAL VAL C . n 
C 2 293 ARG 293 293 293 ARG ARG C . n 
C 2 294 ASP 294 294 294 ASP ASP C . n 
C 2 295 ASP 295 295 295 ASP ASP C . n 
C 2 296 ILE 296 296 296 ILE ILE C . n 
C 2 297 PRO 297 297 297 PRO PRO C . n 
C 2 298 SER 298 298 298 SER SER C . n 
C 2 299 THR 299 299 299 THR THR C . n 
C 2 300 GLN 300 300 300 GLN GLN C . n 
C 2 301 GLU 301 301 301 GLU GLU C . n 
C 2 302 ASN 302 302 302 ASN ASN C . n 
C 2 303 LEU 303 303 303 LEU LEU C . n 
C 2 304 MET 304 304 304 MET MET C . n 
C 2 305 LYS 305 305 305 LYS LYS C . n 
C 2 306 TRP 306 306 306 TRP TRP C . n 
C 2 307 ALA 307 307 307 ALA ALA C . n 
C 2 308 LEU 308 308 308 LEU LEU C . n 
C 2 309 ASP 309 309 309 ASP ASP C . n 
C 2 310 ASN 310 310 310 ASN ASN C . n 
C 2 311 GLY 311 311 311 GLY GLY C . n 
C 2 312 TYR 312 312 312 TYR TYR C . n 
C 2 313 ARG 313 313 313 ARG ARG C . n 
C 2 314 PRO 314 314 314 PRO PRO C . n 
C 2 315 VAL 315 315 315 VAL VAL C . n 
C 2 316 THR 316 316 316 THR THR C . n 
C 2 317 SER 317 317 317 SER SER C . n 
C 2 318 TYR 318 318 318 TYR TYR C . n 
C 2 319 THR 319 319 319 THR THR C . n 
C 2 320 MET 320 320 320 MET MET C . n 
C 2 321 ALA 321 321 321 ALA ALA C . n 
C 2 322 PRO 322 322 322 PRO PRO C . n 
C 2 323 VAL 323 323 323 VAL VAL C . n 
C 2 324 ALA 324 324 324 ALA ALA C . n 
C 2 325 ASN 325 325 325 ASN ASN C . n 
C 2 326 ARG 326 326 326 ARG ARG C . n 
C 2 327 PHE 327 327 327 PHE PHE C . n 
C 2 328 HIS 328 328 328 HIS HIS C . n 
C 2 329 LEU 329 329 329 LEU LEU C . n 
C 2 330 ARG 330 330 330 ARG ARG C . n 
C 2 331 LEU 331 331 331 LEU LEU C . n 
C 2 332 GLU 332 332 332 GLU GLU C . n 
C 2 333 ASN 333 333 333 ASN ASN C . n 
C 2 334 HIS 334 334 ?   ?   ?   C . n 
C 2 335 HIS 335 335 ?   ?   ?   C . n 
C 2 336 HIS 336 336 ?   ?   ?   C . n 
C 2 337 HIS 337 337 ?   ?   ?   C . n 
C 2 338 HIS 338 338 ?   ?   ?   C . n 
C 2 339 HIS 339 339 ?   ?   ?   C . n 
D 3 1   MET 1   4   ?   ?   ?   D . n 
D 3 2   ASN 2   5   ?   ?   ?   D . n 
D 3 3   GLY 3   6   ?   ?   ?   D . n 
D 3 4   ALA 4   7   ?   ?   ?   D . n 
D 3 5   VAL 5   8   ?   ?   ?   D . n 
D 3 6   LYS 6   9   ?   ?   ?   D . n 
D 3 7   PHE 7   10  10  PHE PHE D . n 
D 3 8   PRO 8   11  11  PRO PRO D . n 
D 3 9   GLN 9   12  12  GLN GLN D . n 
D 3 10  LEU 10  13  13  LEU LEU D . n 
D 3 11  CYS 11  14  14  CYS CYS D . n 
D 3 12  LYS 12  15  15  LYS LYS D . n 
D 3 13  PHE 13  16  16  PHE PHE D . n 
D 3 14  CYS 14  17  17  CYS CYS D . n 
D 3 15  ASP 15  18  18  ASP ASP D . n 
D 3 16  VAL 16  19  19  VAL VAL D . n 
D 3 17  ARG 17  20  20  ARG ARG D . n 
D 3 18  PHE 18  21  21  PHE PHE D . n 
D 3 19  SER 19  22  22  SER SER D . n 
D 3 20  THR 20  23  23  THR THR D . n 
D 3 21  CYS 21  24  24  CYS CYS D . n 
D 3 22  ASP 22  25  25  ASP ASP D . n 
D 3 23  ASN 23  26  26  ASN ASN D . n 
D 3 24  GLN 24  27  27  GLN GLN D . n 
D 3 25  LYS 25  28  28  LYS LYS D . n 
D 3 26  SER 26  29  29  SER SER D . n 
D 3 27  CYS 27  30  30  CYS CYS D . n 
D 3 28  MET 28  31  31  MET MET D . n 
D 3 29  SER 29  32  32  SER SER D . n 
D 3 30  ASN 30  33  33  ASN ASN D . n 
D 3 31  CYS 31  34  34  CYS CYS D . n 
D 3 32  SER 32  35  35  SER SER D . n 
D 3 33  ILE 33  36  36  ILE ILE D . n 
D 3 34  THR 34  37  37  THR THR D . n 
D 3 35  SER 35  38  38  SER SER D . n 
D 3 36  ILE 36  39  39  ILE ILE D . n 
D 3 37  CYS 37  40  40  CYS CYS D . n 
D 3 38  GLU 38  41  41  GLU GLU D . n 
D 3 39  LYS 39  42  42  LYS LYS D . n 
D 3 40  PRO 40  43  43  PRO PRO D . n 
D 3 41  GLN 41  44  44  GLN GLN D . n 
D 3 42  GLU 42  45  45  GLU GLU D . n 
D 3 43  VAL 43  46  46  VAL VAL D . n 
D 3 44  CYS 44  47  47  CYS CYS D . n 
D 3 45  VAL 45  48  48  VAL VAL D . n 
D 3 46  ALA 46  49  49  ALA ALA D . n 
D 3 47  VAL 47  50  50  VAL VAL D . n 
D 3 48  TRP 48  51  51  TRP TRP D . n 
D 3 49  ARG 49  52  52  ARG ARG D . n 
D 3 50  LYS 50  53  53  LYS LYS D . n 
D 3 51  ASN 51  54  54  ASN ASN D . n 
D 3 52  ASP 52  55  55  ASP ASP D . n 
D 3 53  GLU 53  56  56  GLU GLU D . n 
D 3 54  ASN 54  57  57  ASN ASN D . n 
D 3 55  ILE 55  58  58  ILE ILE D . n 
D 3 56  THR 56  59  59  THR THR D . n 
D 3 57  LEU 57  60  60  LEU LEU D . n 
D 3 58  GLU 58  61  61  GLU GLU D . n 
D 3 59  THR 59  62  62  THR THR D . n 
D 3 60  VAL 60  63  63  VAL VAL D . n 
D 3 61  CYS 61  64  64  CYS CYS D . n 
D 3 62  HIS 62  65  65  HIS HIS D . n 
D 3 63  ASP 63  66  66  ASP ASP D . n 
D 3 64  PRO 64  67  67  PRO PRO D . n 
D 3 65  LYS 65  68  68  LYS LYS D . n 
D 3 66  LEU 66  69  69  LEU LEU D . n 
D 3 67  PRO 67  70  70  PRO PRO D . n 
D 3 68  TYR 68  71  71  TYR TYR D . n 
D 3 69  HIS 69  72  72  HIS HIS D . n 
D 3 70  ASP 70  73  73  ASP ASP D . n 
D 3 71  PHE 71  74  74  PHE PHE D . n 
D 3 72  ILE 72  75  75  ILE ILE D . n 
D 3 73  LEU 73  76  76  LEU LEU D . n 
D 3 74  GLU 74  77  77  GLU GLU D . n 
D 3 75  ASP 75  78  78  ASP ASP D . n 
D 3 76  ALA 76  79  79  ALA ALA D . n 
D 3 77  ALA 77  80  80  ALA ALA D . n 
D 3 78  SER 78  81  81  SER SER D . n 
D 3 79  PRO 79  82  82  PRO PRO D . n 
D 3 80  LYS 80  83  83  LYS LYS D . n 
D 3 81  CYS 81  84  84  CYS CYS D . n 
D 3 82  ILE 82  85  85  ILE ILE D . n 
D 3 83  MET 83  86  86  MET MET D . n 
D 3 84  LYS 84  87  87  LYS LYS D . n 
D 3 85  GLU 85  88  88  GLU GLU D . n 
D 3 86  LYS 86  89  89  LYS LYS D . n 
D 3 87  LYS 87  90  90  LYS LYS D . n 
D 3 88  LYS 88  91  91  LYS LYS D . n 
D 3 89  PRO 89  92  92  PRO PRO D . n 
D 3 90  GLY 90  93  93  GLY GLY D . n 
D 3 91  GLU 91  94  94  GLU GLU D . n 
D 3 92  THR 92  95  95  THR THR D . n 
D 3 93  PHE 93  96  96  PHE PHE D . n 
D 3 94  PHE 94  97  97  PHE PHE D . n 
D 3 95  MET 95  98  98  MET MET D . n 
D 3 96  CYS 96  99  99  CYS CYS D . n 
D 3 97  SER 97  100 100 SER SER D . n 
D 3 98  CYS 98  101 101 CYS CYS D . n 
D 3 99  SER 99  102 102 SER SER D . n 
D 3 100 SER 100 103 103 SER SER D . n 
D 3 101 ASP 101 104 104 ASP ASP D . n 
D 3 102 GLU 102 105 105 GLU GLU D . n 
D 3 103 CYS 103 106 106 CYS CYS D . n 
D 3 104 ASN 104 107 107 ASN ASN D . n 
D 3 105 ASP 105 108 108 ASP ASP D . n 
D 3 106 ASN 106 109 109 ASN ASN D . n 
D 3 107 ILE 107 110 110 ILE ILE D . n 
D 3 108 ILE 108 111 111 ILE ILE D . n 
D 3 109 PHE 109 112 112 PHE PHE D . n 
D 3 110 SER 110 113 113 SER SER D . n 
D 3 111 GLU 111 114 114 GLU GLU D . n 
D 3 112 GLU 112 115 115 GLU GLU D . n 
D 3 113 TYR 113 116 116 TYR TYR D . n 
E 3 1   MET 1   4   ?   ?   ?   E . n 
E 3 2   ASN 2   5   ?   ?   ?   E . n 
E 3 3   GLY 3   6   ?   ?   ?   E . n 
E 3 4   ALA 4   7   ?   ?   ?   E . n 
E 3 5   VAL 5   8   8   VAL VAL E . n 
E 3 6   LYS 6   9   9   LYS LYS E . n 
E 3 7   PHE 7   10  10  PHE PHE E . n 
E 3 8   PRO 8   11  11  PRO PRO E . n 
E 3 9   GLN 9   12  12  GLN GLN E . n 
E 3 10  LEU 10  13  13  LEU LEU E . n 
E 3 11  CYS 11  14  14  CYS CYS E . n 
E 3 12  LYS 12  15  15  LYS LYS E . n 
E 3 13  PHE 13  16  16  PHE PHE E . n 
E 3 14  CYS 14  17  17  CYS CYS E . n 
E 3 15  ASP 15  18  18  ASP ASP E . n 
E 3 16  VAL 16  19  19  VAL VAL E . n 
E 3 17  ARG 17  20  20  ARG ARG E . n 
E 3 18  PHE 18  21  21  PHE PHE E . n 
E 3 19  SER 19  22  22  SER SER E . n 
E 3 20  THR 20  23  23  THR THR E . n 
E 3 21  CYS 21  24  24  CYS CYS E . n 
E 3 22  ASP 22  25  25  ASP ASP E . n 
E 3 23  ASN 23  26  26  ASN ASN E . n 
E 3 24  GLN 24  27  27  GLN GLN E . n 
E 3 25  LYS 25  28  28  LYS LYS E . n 
E 3 26  SER 26  29  29  SER SER E . n 
E 3 27  CYS 27  30  30  CYS CYS E . n 
E 3 28  MET 28  31  31  MET MET E . n 
E 3 29  SER 29  32  32  SER SER E . n 
E 3 30  ASN 30  33  33  ASN ASN E . n 
E 3 31  CYS 31  34  34  CYS CYS E . n 
E 3 32  SER 32  35  35  SER SER E . n 
E 3 33  ILE 33  36  36  ILE ILE E . n 
E 3 34  THR 34  37  37  THR THR E . n 
E 3 35  SER 35  38  38  SER SER E . n 
E 3 36  ILE 36  39  39  ILE ILE E . n 
E 3 37  CYS 37  40  40  CYS CYS E . n 
E 3 38  GLU 38  41  41  GLU GLU E . n 
E 3 39  LYS 39  42  42  LYS LYS E . n 
E 3 40  PRO 40  43  43  PRO PRO E . n 
E 3 41  GLN 41  44  44  GLN GLN E . n 
E 3 42  GLU 42  45  45  GLU GLU E . n 
E 3 43  VAL 43  46  46  VAL VAL E . n 
E 3 44  CYS 44  47  47  CYS CYS E . n 
E 3 45  VAL 45  48  48  VAL VAL E . n 
E 3 46  ALA 46  49  49  ALA ALA E . n 
E 3 47  VAL 47  50  50  VAL VAL E . n 
E 3 48  TRP 48  51  51  TRP TRP E . n 
E 3 49  ARG 49  52  52  ARG ARG E . n 
E 3 50  LYS 50  53  53  LYS LYS E . n 
E 3 51  ASN 51  54  54  ASN ASN E . n 
E 3 52  ASP 52  55  55  ASP ASP E . n 
E 3 53  GLU 53  56  56  GLU GLU E . n 
E 3 54  ASN 54  57  57  ASN ASN E . n 
E 3 55  ILE 55  58  58  ILE ILE E . n 
E 3 56  THR 56  59  59  THR THR E . n 
E 3 57  LEU 57  60  60  LEU LEU E . n 
E 3 58  GLU 58  61  61  GLU GLU E . n 
E 3 59  THR 59  62  62  THR THR E . n 
E 3 60  VAL 60  63  63  VAL VAL E . n 
E 3 61  CYS 61  64  64  CYS CYS E . n 
E 3 62  HIS 62  65  65  HIS HIS E . n 
E 3 63  ASP 63  66  66  ASP ASP E . n 
E 3 64  PRO 64  67  67  PRO PRO E . n 
E 3 65  LYS 65  68  68  LYS LYS E . n 
E 3 66  LEU 66  69  69  LEU LEU E . n 
E 3 67  PRO 67  70  70  PRO PRO E . n 
E 3 68  TYR 68  71  71  TYR TYR E . n 
E 3 69  HIS 69  72  72  HIS HIS E . n 
E 3 70  ASP 70  73  73  ASP ASP E . n 
E 3 71  PHE 71  74  74  PHE PHE E . n 
E 3 72  ILE 72  75  75  ILE ILE E . n 
E 3 73  LEU 73  76  76  LEU LEU E . n 
E 3 74  GLU 74  77  77  GLU GLU E . n 
E 3 75  ASP 75  78  78  ASP ASP E . n 
E 3 76  ALA 76  79  79  ALA ALA E . n 
E 3 77  ALA 77  80  80  ALA ALA E . n 
E 3 78  SER 78  81  81  SER SER E . n 
E 3 79  PRO 79  82  82  PRO PRO E . n 
E 3 80  LYS 80  83  83  LYS LYS E . n 
E 3 81  CYS 81  84  84  CYS CYS E . n 
E 3 82  ILE 82  85  85  ILE ILE E . n 
E 3 83  MET 83  86  86  MET MET E . n 
E 3 84  LYS 84  87  87  LYS LYS E . n 
E 3 85  GLU 85  88  88  GLU GLU E . n 
E 3 86  LYS 86  89  89  LYS LYS E . n 
E 3 87  LYS 87  90  90  LYS LYS E . n 
E 3 88  LYS 88  91  91  LYS LYS E . n 
E 3 89  PRO 89  92  92  PRO PRO E . n 
E 3 90  GLY 90  93  93  GLY GLY E . n 
E 3 91  GLU 91  94  94  GLU GLU E . n 
E 3 92  THR 92  95  95  THR THR E . n 
E 3 93  PHE 93  96  96  PHE PHE E . n 
E 3 94  PHE 94  97  97  PHE PHE E . n 
E 3 95  MET 95  98  98  MET MET E . n 
E 3 96  CYS 96  99  99  CYS CYS E . n 
E 3 97  SER 97  100 100 SER SER E . n 
E 3 98  CYS 98  101 101 CYS CYS E . n 
E 3 99  SER 99  102 102 SER SER E . n 
E 3 100 SER 100 103 103 SER SER E . n 
E 3 101 ASP 101 104 104 ASP ASP E . n 
E 3 102 GLU 102 105 105 GLU GLU E . n 
E 3 103 CYS 103 106 106 CYS CYS E . n 
E 3 104 ASN 104 107 107 ASN ASN E . n 
E 3 105 ASP 105 108 108 ASP ASP E . n 
E 3 106 ASN 106 109 109 ASN ASN E . n 
E 3 107 ILE 107 110 110 ILE ILE E . n 
E 3 108 ILE 108 111 111 ILE ILE E . n 
E 3 109 PHE 109 112 112 PHE PHE E . n 
E 3 110 SER 110 113 113 SER SER E . n 
E 3 111 GLU 111 114 114 GLU GLU E . n 
E 3 112 GLU 112 115 115 GLU GLU E . n 
E 3 113 TYR 113 116 116 TYR TYR E . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FDY 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FDY 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FDY 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9FDY 
_struct.title                        'Betaglycan Orphan Domain (ratBGo) in complex with TGF-b1 and extracellular domain of TGFBRII' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FDY 
_struct_keywords.text            'Complex, Betaglycan, TGFBR3, TGFb1, TGFBR2, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP TGFB1_HUMAN P01137 ? 1 
;ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVP
QALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
;
279 
2 UNP TGBR3_RAT   P26342 ? 2 
;CELSPINASHPVQALMESFTVLSGCASRGTTGLPREVHVLNLRSTDQGPGQRQREVTLHLNPIASVHTHHKPIVFLLNSP
QPLVWHLKTERLAAGVPRLFLVSEGSVVQFPSGNFSLTAETEERNFPQENEHLLRWAQKEYGAVTSFTELKIARNIYIKV
GEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLPSQPHEKEVHIIELITPSSNPYSAFQVDIIVDIRPAQEDPEVVK
NLVLILKCKKSVNWVIKSFDVKGNLKVIAPNSIGFGKESERSMTMTKLVRDDIPSTQENLMKWALDNGYRPVTSYTMAPV
ANRFHLRLEN
;
31  
3 UNP TGFR2_HUMAN P37173 ? 3 
;NGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKC
IMKEKKKPGETFFMCSCSSDECNDNIIFSEEY
;
42  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9FDY A 1 ? 112 ? P01137 279 ? 390 ? 1 112 
2 1 9FDY B 1 ? 112 ? P01137 279 ? 390 ? 1 112 
3 2 9FDY C 4 ? 333 ? P26342 31  ? 360 ? 4 333 
4 3 9FDY D 2 ? 113 ? P37173 42  ? 153 ? 5 116 
5 3 9FDY E 2 ? 113 ? P37173 42  ? 153 ? 5 116 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 9FDY GLY C 1   ? UNP P26342 ? ? 'expression tag'        1   1  
3 9FDY SER C 2   ? UNP P26342 ? ? 'expression tag'        2   2  
3 9FDY PRO C 3   ? UNP P26342 ? ? 'expression tag'        3   3  
3 9FDY HIS C 334 ? UNP P26342 ? ? 'expression tag'        334 4  
3 9FDY HIS C 335 ? UNP P26342 ? ? 'expression tag'        335 5  
3 9FDY HIS C 336 ? UNP P26342 ? ? 'expression tag'        336 6  
3 9FDY HIS C 337 ? UNP P26342 ? ? 'expression tag'        337 7  
3 9FDY HIS C 338 ? UNP P26342 ? ? 'expression tag'        338 8  
3 9FDY HIS C 339 ? UNP P26342 ? ? 'expression tag'        339 9  
4 9FDY MET D 1   ? UNP P37173 ? ? 'initiating methionine' 4   10 
5 9FDY MET E 1   ? UNP P37173 ? ? 'initiating methionine' 4   11 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 3   ? SER A 10  ? ASP A 3   SER A 10  1 ? 8  
HELX_P HELX_P2  AA2 THR A 56  ? ASN A 69  ? THR A 56  ASN A 69  1 ? 14 
HELX_P HELX_P3  AA3 THR B 4   ? SER B 10  ? THR B 4   SER B 10  1 ? 7  
HELX_P HELX_P4  AA4 THR B 56  ? ASN B 69  ? THR B 56  ASN B 69  1 ? 14 
HELX_P HELX_P5  AA5 ASN C 117 ? LEU C 120 ? ASN C 117 LEU C 120 5 ? 4  
HELX_P HELX_P6  AA6 GLU C 132 ? GLY C 145 ? GLU C 132 GLY C 145 1 ? 14 
HELX_P HELX_P7  AA7 LYS C 280 ? ARG C 284 ? LYS C 280 ARG C 284 5 ? 5  
HELX_P HELX_P8  AA8 THR C 299 ? GLY C 311 ? THR C 299 GLY C 311 1 ? 13 
HELX_P HELX_P9  AA9 LEU D 73  ? SER D 78  ? LEU D 76  SER D 81  5 ? 6  
HELX_P HELX_P10 AB1 PRO E 67  ? PHE E 71  ? PRO E 70  PHE E 74  5 ? 5  
HELX_P HELX_P11 AB2 GLU E 102 ? ASN E 104 ? GLU E 105 ASN E 107 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 7  SG ? ? ? 1_555 A CYS 16  SG ? ? A CYS 7   A CYS 16  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf2  disulf ? ? A CYS 15 SG ? ? ? 1_555 A CYS 78  SG ? ? A CYS 15  A CYS 78  1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf3  disulf ? ? A CYS 44 SG ? ? ? 1_555 A CYS 109 SG ? ? A CYS 44  A CYS 109 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf4  disulf ? ? A CYS 48 SG ? ? ? 1_555 A CYS 111 SG ? ? A CYS 48  A CYS 111 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf5  disulf ? ? A CYS 77 SG ? ? ? 1_555 B CYS 77  SG ? ? A CYS 77  B CYS 77  1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf6  disulf ? ? B CYS 7  SG ? ? ? 1_555 B CYS 16  SG ? ? B CYS 7   B CYS 16  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf7  disulf ? ? B CYS 15 SG ? ? ? 1_555 B CYS 78  SG ? ? B CYS 15  B CYS 78  1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf8  disulf ? ? B CYS 44 SG ? ? ? 1_555 B CYS 109 SG ? ? B CYS 44  B CYS 109 1_555 ? ? ? ? ? ? ? 2.026 ? ? 
disulf9  disulf ? ? B CYS 48 SG ? ? ? 1_555 B CYS 111 SG ? ? B CYS 48  B CYS 111 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf10 disulf ? ? C CYS 4  SG ? ? ? 1_555 C CYS 197 SG ? ? C CYS 4   C CYS 197 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf11 disulf ? ? C CYS 28 SG ? ? ? 1_555 C CYS 173 SG ? ? C CYS 28  C CYS 173 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf12 disulf ? ? D CYS 11 SG ? ? ? 1_555 D CYS 44  SG ? ? D CYS 14  D CYS 47  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf13 disulf ? ? D CYS 14 SG ? ? ? 1_555 D CYS 31  SG ? ? D CYS 17  D CYS 34  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf14 disulf ? ? D CYS 21 SG ? ? ? 1_555 D CYS 27  SG ? ? D CYS 24  D CYS 30  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf15 disulf ? ? D CYS 37 SG ? ? ? 1_555 D CYS 61  SG ? ? D CYS 40  D CYS 64  1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf16 disulf ? ? D CYS 81 SG ? ? ? 1_555 D CYS 96  SG ? ? D CYS 84  D CYS 99  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf17 disulf ? ? D CYS 98 SG ? ? ? 1_555 D CYS 103 SG ? ? D CYS 101 D CYS 106 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf18 disulf ? ? E CYS 11 SG ? ? ? 1_555 E CYS 44  SG ? ? E CYS 14  E CYS 47  1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf19 disulf ? ? E CYS 14 SG ? ? ? 1_555 E CYS 31  SG ? ? E CYS 17  E CYS 34  1_555 ? ? ? ? ? ? ? 2.026 ? ? 
disulf20 disulf ? ? E CYS 21 SG ? ? ? 1_555 E CYS 27  SG ? ? E CYS 24  E CYS 30  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf21 disulf ? ? E CYS 37 SG ? ? ? 1_555 E CYS 61  SG ? ? E CYS 40  E CYS 64  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf22 disulf ? ? E CYS 81 SG ? ? ? 1_555 E CYS 96  SG ? ? E CYS 84  E CYS 99  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf23 disulf ? ? E CYS 98 SG ? ? ? 1_555 E CYS 103 SG ? ? E CYS 101 E CYS 106 1_555 ? ? ? ? ? ? ? 2.026 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  CYS A 7  ? CYS A 16  ? CYS A 7   ? 1_555 CYS A 16  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2  CYS A 15 ? CYS A 78  ? CYS A 15  ? 1_555 CYS A 78  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3  CYS A 44 ? CYS A 109 ? CYS A 44  ? 1_555 CYS A 109 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4  CYS A 48 ? CYS A 111 ? CYS A 48  ? 1_555 CYS A 111 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5  CYS A 77 ? CYS B 77  ? CYS A 77  ? 1_555 CYS B 77  ? 1_555 SG SG . . . None 'Disulfide bridge' 
6  CYS B 7  ? CYS B 16  ? CYS B 7   ? 1_555 CYS B 16  ? 1_555 SG SG . . . None 'Disulfide bridge' 
7  CYS B 15 ? CYS B 78  ? CYS B 15  ? 1_555 CYS B 78  ? 1_555 SG SG . . . None 'Disulfide bridge' 
8  CYS B 44 ? CYS B 109 ? CYS B 44  ? 1_555 CYS B 109 ? 1_555 SG SG . . . None 'Disulfide bridge' 
9  CYS B 48 ? CYS B 111 ? CYS B 48  ? 1_555 CYS B 111 ? 1_555 SG SG . . . None 'Disulfide bridge' 
10 CYS C 4  ? CYS C 197 ? CYS C 4   ? 1_555 CYS C 197 ? 1_555 SG SG . . . None 'Disulfide bridge' 
11 CYS C 28 ? CYS C 173 ? CYS C 28  ? 1_555 CYS C 173 ? 1_555 SG SG . . . None 'Disulfide bridge' 
12 CYS D 11 ? CYS D 44  ? CYS D 14  ? 1_555 CYS D 47  ? 1_555 SG SG . . . None 'Disulfide bridge' 
13 CYS D 14 ? CYS D 31  ? CYS D 17  ? 1_555 CYS D 34  ? 1_555 SG SG . . . None 'Disulfide bridge' 
14 CYS D 21 ? CYS D 27  ? CYS D 24  ? 1_555 CYS D 30  ? 1_555 SG SG . . . None 'Disulfide bridge' 
15 CYS D 37 ? CYS D 61  ? CYS D 40  ? 1_555 CYS D 64  ? 1_555 SG SG . . . None 'Disulfide bridge' 
16 CYS D 81 ? CYS D 96  ? CYS D 84  ? 1_555 CYS D 99  ? 1_555 SG SG . . . None 'Disulfide bridge' 
17 CYS D 98 ? CYS D 103 ? CYS D 101 ? 1_555 CYS D 106 ? 1_555 SG SG . . . None 'Disulfide bridge' 
18 CYS E 11 ? CYS E 44  ? CYS E 14  ? 1_555 CYS E 47  ? 1_555 SG SG . . . None 'Disulfide bridge' 
19 CYS E 14 ? CYS E 31  ? CYS E 17  ? 1_555 CYS E 34  ? 1_555 SG SG . . . None 'Disulfide bridge' 
20 CYS E 21 ? CYS E 27  ? CYS E 24  ? 1_555 CYS E 30  ? 1_555 SG SG . . . None 'Disulfide bridge' 
21 CYS E 37 ? CYS E 61  ? CYS E 40  ? 1_555 CYS E 64  ? 1_555 SG SG . . . None 'Disulfide bridge' 
22 CYS E 81 ? CYS E 96  ? CYS E 84  ? 1_555 CYS E 99  ? 1_555 SG SG . . . None 'Disulfide bridge' 
23 CYS E 98 ? CYS E 103 ? CYS E 101 ? 1_555 CYS E 106 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLU 35  A . ? GLU 35  A PRO 36  A ? PRO 36  A 1 -2.79 
2 GLU 35  B . ? GLU 35  B PRO 36  B ? PRO 36  B 1 1.06  
3 ASP 238 C . ? ASP 238 C PRO 239 C ? PRO 239 C 1 -0.51 
4 ARG 313 C . ? ARG 313 C PRO 314 C ? PRO 314 C 1 -4.38 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 5 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 7 ? 
AA8 ? 4 ? 
AA9 ? 9 ? 
AB1 ? 6 ? 
AB2 ? 5 ? 
AB3 ? 2 ? 
AB4 ? 5 ? 
AB5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? parallel      
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? parallel      
AA7 4 5 ? parallel      
AA7 5 6 ? parallel      
AA7 6 7 ? parallel      
AA8 1 2 ? parallel      
AA8 2 3 ? parallel      
AA8 3 4 ? parallel      
AA9 1 2 ? parallel      
AA9 2 3 ? parallel      
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AA9 6 7 ? parallel      
AA9 7 8 ? parallel      
AA9 8 9 ? parallel      
AB1 1 2 ? anti-parallel 
AB1 2 3 ? parallel      
AB1 3 4 ? parallel      
AB1 4 5 ? parallel      
AB1 5 6 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 CYS A 16  ? ARG A 18  ? CYS A 16  ARG A 18  
AA1 2 PHE A 43  ? LEU A 45  ? PHE A 43  LEU A 45  
AA2 1 TYR A 21  ? ASP A 23  ? TYR A 21  ASP A 23  
AA2 2 GLY A 38  ? HIS A 40  ? GLY A 38  HIS A 40  
AA3 1 LYS A 95  ? SER A 112 ? LYS A 95  SER A 112 
AA3 2 CYS A 77  ? VAL A 92  ? CYS A 77  VAL A 92  
AA3 3 THR D 34  ? ILE D 36  ? THR D 37  ILE D 39  
AA3 4 LEU D 10  ? LYS D 12  ? LEU D 13  LYS D 15  
AA4 1 LEU B 2   ? ASP B 3   ? LEU B 2   ASP B 3   
AA4 2 LYS B 95  ? SER B 112 ? LYS B 95  SER B 112 
AA4 3 CYS B 77  ? VAL B 92  ? CYS B 77  VAL B 92  
AA4 4 THR E 34  ? ILE E 36  ? THR E 37  ILE E 39  
AA4 5 LEU E 10  ? LYS E 12  ? LEU E 13  LYS E 15  
AA5 1 CYS B 16  ? ARG B 18  ? CYS B 16  ARG B 18  
AA5 2 PHE B 43  ? LEU B 45  ? PHE B 43  LEU B 45  
AA6 1 TYR B 21  ? ASP B 23  ? TYR B 21  ASP B 23  
AA6 2 GLY B 38  ? HIS B 40  ? GLY B 38  HIS B 40  
AA7 1 SER C 7   ? PRO C 8   ? SER C 7   PRO C 8   
AA7 2 GLU C 195 ? VAL C 198 ? GLU C 195 VAL C 198 
AA7 3 SER C 317 ? VAL C 323 ? SER C 317 VAL C 323 
AA7 4 LYS C 206 ? THR C 215 ? LYS C 206 THR C 215 
AA7 5 VAL C 241 ? CYS C 251 ? VAL C 241 CYS C 251 
AA7 6 VAL C 264 ? ILE C 271 ? VAL C 264 ILE C 271 
AA7 7 THR C 287 ? LEU C 291 ? THR C 287 LEU C 291 
AA8 1 LYS C 91  ? THR C 92  ? LYS C 91  THR C 92  
AA8 2 GLU C 58  ? PRO C 65  ? GLU C 58  PRO C 65  
AA8 3 VAL C 87  ? TRP C 88  ? VAL C 87  TRP C 88  
AA8 4 VAL C 110 ? VAL C 111 ? VAL C 110 VAL C 111 
AA9 1 LYS C 91  ? THR C 92  ? LYS C 91  THR C 92  
AA9 2 GLU C 58  ? PRO C 65  ? GLU C 58  PRO C 65  
AA9 3 ASN C 158 ? VAL C 163 ? ASN C 158 VAL C 163 
AA9 4 LEU C 185 ? LYS C 192 ? LEU C 185 LYS C 192 
AA9 5 VAL C 15  ? THR C 23  ? VAL C 15  THR C 23  
AA9 6 ARG C 326 ? LEU C 331 ? ARG C 326 LEU C 331 
AA9 7 ILE C 229 ? PRO C 234 ? ILE C 229 PRO C 234 
AA9 8 ASN C 256 ? SER C 261 ? ASN C 256 SER C 261 
AA9 9 SER C 275 ? PHE C 278 ? SER C 275 PHE C 278 
AB1 1 SER C 26  ? ALA C 29  ? SER C 26  ALA C 29  
AB1 2 SER C 149 ? LYS C 154 ? SER C 149 LYS C 154 
AB1 3 GLU C 39  ? ARG C 46  ? GLU C 39  ARG C 46  
AB1 4 ILE C 76  ? ASN C 81  ? ILE C 76  ASN C 81  
AB1 5 ARG C 101 ? SER C 106 ? ARG C 101 SER C 106 
AB1 6 ALA C 122 ? ARG C 127 ? ALA C 122 ARG C 127 
AB2 1 CYS D 14  ? ARG D 17  ? CYS D 17  ARG D 20  
AB2 2 LEU D 57  ? HIS D 62  ? LEU D 60  HIS D 65  
AB2 3 VAL D 43  ? TRP D 48  ? VAL D 46  TRP D 51  
AB2 4 PHE D 93  ? CYS D 98  ? PHE D 96  CYS D 101 
AB2 5 LYS D 84  ? LYS D 86  ? LYS D 87  LYS D 89  
AB3 1 SER D 26  ? MET D 28  ? SER D 29  MET D 31  
AB3 2 ASN D 106 ? ILE D 108 ? ASN D 109 ILE D 111 
AB4 1 ARG E 17  ? PHE E 18  ? ARG E 20  PHE E 21  
AB4 2 ILE E 55  ? HIS E 62  ? ILE E 58  HIS E 65  
AB4 3 VAL E 43  ? LYS E 50  ? VAL E 46  LYS E 53  
AB4 4 THR E 92  ? CYS E 98  ? THR E 95  CYS E 101 
AB4 5 LYS E 84  ? LYS E 86  ? LYS E 87  LYS E 89  
AB5 1 SER E 26  ? MET E 28  ? SER E 29  MET E 31  
AB5 2 ASN E 106 ? ILE E 108 ? ASN E 109 ILE E 111 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ARG A 18  ? N ARG A 18  O PHE A 43  ? O PHE A 43  
AA2 1 2 N ILE A 22  ? N ILE A 22  O TYR A 39  ? O TYR A 39  
AA3 1 2 O ARG A 107 ? O ARG A 107 N ALA A 82  ? N ALA A 82  
AA3 2 3 N TYR A 91  ? N TYR A 91  O ILE D 36  ? O ILE D 39  
AA3 3 4 O SER D 35  ? O SER D 38  N CYS D 11  ? N CYS D 14  
AA4 1 2 N LEU B 2   ? N LEU B 2   O CYS B 109 ? O CYS B 109 
AA4 2 3 O ILE B 105 ? O ILE B 105 N GLU B 84  ? N GLU B 84  
AA4 3 4 N TYR B 91  ? N TYR B 91  O ILE E 36  ? O ILE E 39  
AA4 4 5 O SER E 35  ? O SER E 38  N CYS E 11  ? N CYS E 14  
AA5 1 2 N CYS B 16  ? N CYS B 16  O LEU B 45  ? O LEU B 45  
AA6 1 2 N ILE B 22  ? N ILE B 22  O TYR B 39  ? O TYR B 39  
AA7 1 2 N SER C 7   ? N SER C 7   O GLY C 196 ? O GLY C 196 
AA7 2 3 N CYS C 197 ? N CYS C 197 O TYR C 318 ? O TYR C 318 
AA7 3 4 O THR C 319 ? O THR C 319 N GLU C 212 ? N GLU C 212 
AA7 4 5 N ILE C 211 ? N ILE C 211 O ILE C 248 ? O ILE C 248 
AA7 5 6 N LEU C 247 ? N LEU C 247 O ILE C 271 ? O ILE C 271 
AA7 6 7 N GLY C 266 ? N GLY C 266 O THR C 287 ? O THR C 287 
AA8 1 2 O LYS C 91  ? O LYS C 91  N LEU C 63  ? N LEU C 63  
AA8 2 3 N VAL C 59  ? N VAL C 59  O VAL C 87  ? O VAL C 87  
AA8 3 4 N TRP C 88  ? N TRP C 88  O VAL C 110 ? O VAL C 110 
AA9 1 2 O LYS C 91  ? O LYS C 91  N LEU C 63  ? N LEU C 63  
AA9 2 3 N ASN C 64  ? N ASN C 64  O VAL C 163 ? O VAL C 163 
AA9 3 4 N TYR C 160 ? N TYR C 160 O LEU C 185 ? O LEU C 185 
AA9 4 5 O TYR C 188 ? O TYR C 188 N SER C 21  ? N SER C 21  
AA9 5 6 N GLN C 16  ? N GLN C 16  O HIS C 328 ? O HIS C 328 
AA9 6 7 O LEU C 329 ? O LEU C 329 N ASP C 231 ? N ASP C 231 
AA9 7 8 N VAL C 230 ? N VAL C 230 O VAL C 258 ? O VAL C 258 
AA9 8 9 N TRP C 257 ? N TRP C 257 O GLY C 277 ? O GLY C 277 
AB1 1 2 N CYS C 28  ? N CYS C 28  O PHE C 150 ? O PHE C 150 
AB1 2 3 O THR C 151 ? O THR C 151 N ASN C 44  ? N ASN C 44  
AB1 3 4 N HIS C 41  ? N HIS C 41  O LEU C 79  ? O LEU C 79  
AB1 4 5 N ILE C 76  ? N ILE C 76  O LEU C 102 ? O LEU C 102 
AB1 5 6 N ARG C 101 ? N ARG C 101 O GLU C 123 ? O GLU C 123 
AB2 1 2 N ARG D 17  ? N ARG D 20  O LEU D 57  ? O LEU D 60  
AB2 2 3 O HIS D 62  ? O HIS D 65  N VAL D 43  ? N VAL D 46  
AB2 3 4 N TRP D 48  ? N TRP D 51  O PHE D 94  ? O PHE D 97  
AB2 4 5 O PHE D 93  ? O PHE D 96  N LYS D 86  ? N LYS D 89  
AB3 1 2 N CYS D 27  ? N CYS D 30  O ILE D 107 ? O ILE D 110 
AB4 1 2 N ARG E 17  ? N ARG E 20  O LEU E 57  ? O LEU E 60  
AB4 2 3 O HIS E 62  ? O HIS E 65  N VAL E 43  ? N VAL E 46  
AB4 3 4 N ALA E 46  ? N ALA E 49  O CYS E 96  ? O CYS E 99  
AB4 4 5 O MET E 95  ? O MET E 98  N LYS E 84  ? N LYS E 87  
AB5 1 2 N CYS E 27  ? N CYS E 30  O ILE E 107 ? O ILE E 110 
# 
_pdbx_entry_details.entry_id                   9FDY 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OD1 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   ASP 
_pdbx_validate_close_contact.auth_seq_id_1    3 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OG 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   SER 
_pdbx_validate_close_contact.auth_seq_id_2    108 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.16 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 2   ? ? -90.46  57.03   
2  1 TRP A 52  ? ? -160.63 -168.93 
3  1 SER A 73  ? ? 67.90   -3.77   
4  1 LEU B 2   ? ? -91.72  52.39   
5  1 ILE C 214 ? ? -92.88  -61.09  
6  1 TYR C 221 ? ? -98.39  37.63   
7  1 TRP C 257 ? ? -36.97  120.45  
8  1 ASN C 325 ? ? -154.41 19.19   
9  1 ARG C 326 ? ? -142.83 52.50   
10 1 ASP D 18  ? ? -79.97  -167.39 
11 1 ASP E 18  ? ? -76.34  -163.91 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9FDY 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   AlphaFold 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    9FDY 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'FOURIER SPACE' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               235089 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 RECOMBINANT COMPLEX 
'Ternary complex of Rat Betaglycan Orphan Domain (ratBGo) with TGF-B1 and extracellular domains of TGFBRII' ? ? ? '1, 2, 3' 
2 1 RECOMBINANT COMPLEX 'Transforming growth factor beta-1' ? ? ? 1         
3 1 RECOMBINANT COMPLEX 'Transforming growth factor beta receptor type-3, Orphan domain' ? ? ? 2         
4 1 RECOMBINANT COMPLEX 'Transforming growth factor beta receptor type-2, extracellular domain' ? ? ? 3         
# 
_em_imaging.entry_id                        9FDY 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             3500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        'UltrAuFoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9FDY 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9FDY 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 C GLY 1   ? C GLY 1   
2  1 Y 1 C SER 2   ? C SER 2   
3  1 Y 1 C PRO 3   ? C PRO 3   
4  1 Y 1 C HIS 334 ? C HIS 334 
5  1 Y 1 C HIS 335 ? C HIS 335 
6  1 Y 1 C HIS 336 ? C HIS 336 
7  1 Y 1 C HIS 337 ? C HIS 337 
8  1 Y 1 C HIS 338 ? C HIS 338 
9  1 Y 1 C HIS 339 ? C HIS 339 
10 1 Y 1 D MET 4   ? D MET 1   
11 1 Y 1 D ASN 5   ? D ASN 2   
12 1 Y 1 D GLY 6   ? D GLY 3   
13 1 Y 1 D ALA 7   ? D ALA 4   
14 1 Y 1 D VAL 8   ? D VAL 5   
15 1 Y 1 D LYS 9   ? D LYS 6   
16 1 Y 1 E MET 4   ? E MET 1   
17 1 Y 1 E ASN 5   ? E ASN 2   
18 1 Y 1 E GLY 6   ? E GLY 3   
19 1 Y 1 E ALA 7   ? E ALA 4   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-17 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9FDY 
_em_admin.last_update        2025-03-12 
_em_admin.map_release_date   2025-03-12 
_em_admin.title              'Betaglycan Orphan Domain (ratBGo) in complex with TGF-b1 and extracellular domain of TGFBRII' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 150 mM NaCl       1 'sodium cholride' 
1 20  mM C8H18N2O4S 2 HEPES             
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
loop_
_em_entity_assembly_molwt.entity_assembly_id 
_em_entity_assembly_molwt.experimental_flag 
_em_entity_assembly_molwt.id 
_em_entity_assembly_molwt.units 
_em_entity_assembly_molwt.value 
1 NO  1 MEGADALTONS 0.088 
1 YES 2 MEGADALTONS 0.025 
1 YES 3 MEGADALTONS 0.038 
1 YES 4 MEGADALTONS 0.012 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 2 9606  'Homo sapiens'      ? ? ? ? ? 
? ? 2 3 9606  'Homo sapiens'      ? ? ? ? ? 
? ? 3 4 10116 'Rattus norvegicus' ? ? ? ? ? 
? ? 4 5 9606  'Homo sapiens'      ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 1 2 9606 'Homo sapiens'     ? ? 
? 2 3 9606 'Homo sapiens'     ? ? 
? 3 4 9606 'Homo sapiens'     ? ? 
? 4 5 562  'Escherichia coli' ? ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   4000000 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       Initial 1  1 ? ? crYOLO          1.7 
'PARTICLE SELECTION'       final   2  1 ? ? Topaz           ?   
'IMAGE ACQUISITION'        ?       3  ? ? 1 EPU             ?   
MASKING                    ?       4  ? ? ? ?               ?   
'CTF CORRECTION'           ?       5  1 ? ? Gctf            ?   
'LAYERLINE INDEXING'       ?       6  ? ? ? ?               ?   
'DIFFRACTION INDEXING'     ?       7  ? ? ? ?               ?   
'MODEL FITTING'            ?       8  ? 1 ? 'UCSF ChimeraX' ?   
OTHER                      ?       9  ? ? ? ?               ?   
'MODEL REFINEMENT'         ?       10 ? 1 ? PHENIX          ?   
'INITIAL EULER ASSIGNMENT' ?       11 1 ? ? cryoSPARC       v4  
'FINAL EULER ASSIGNMENT'   ?       12 1 ? ? cryoSPARC       v4  
CLASSIFICATION             ?       13 1 ? ? RELION          4.0 
RECONSTRUCTION             ?       14 1 ? ? cryoSPARC       4   
# 
_em_specimen.concentration           0.6 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'H2020 Marie Curie Actions of the European Commission'                                     'European Union' 893196   1 
'The Francis Crick Institute'                                                              'United Kingdom' CC2021   2 
'The Francis Crick Institute'                                                              'United Kingdom' CC2058   3 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States'  GM058670 4 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9FDY 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 1   ? 143.779 119.977 117.796 1.00 113.18 ? 1   ALA A N   1 
ATOM 2    C CA  . ALA A 1 1   ? 144.835 119.133 117.249 1.00 114.59 ? 1   ALA A CA  1 
ATOM 3    C C   . ALA A 1 1   ? 144.271 118.143 116.238 1.00 117.68 ? 1   ALA A C   1 
ATOM 4    O O   . ALA A 1 1   ? 145.008 117.350 115.653 1.00 118.68 ? 1   ALA A O   1 
ATOM 5    C CB  . ALA A 1 1   ? 145.556 118.397 118.366 1.00 108.39 ? 1   ALA A CB  1 
ATOM 6    N N   . LEU A 1 2   ? 142.956 118.194 116.037 1.00 115.72 ? 2   LEU A N   1 
ATOM 7    C CA  . LEU A 1 2   ? 142.276 117.298 115.103 1.00 114.94 ? 2   LEU A CA  1 
ATOM 8    C C   . LEU A 1 2   ? 142.215 117.924 113.709 1.00 116.82 ? 2   LEU A C   1 
ATOM 9    O O   . LEU A 1 2   ? 141.154 118.103 113.116 1.00 119.11 ? 2   LEU A O   1 
ATOM 10   C CB  . LEU A 1 2   ? 140.884 116.960 115.620 1.00 113.54 ? 2   LEU A CB  1 
ATOM 11   C CG  . LEU A 1 2   ? 140.814 116.434 117.052 1.00 106.96 ? 2   LEU A CG  1 
ATOM 12   C CD1 . LEU A 1 2   ? 139.373 116.195 117.455 1.00 96.57  ? 2   LEU A CD1 1 
ATOM 13   C CD2 . LEU A 1 2   ? 141.627 115.162 117.194 1.00 107.40 ? 2   LEU A CD2 1 
ATOM 14   N N   . ASP A 1 3   ? 143.393 118.254 113.187 1.00 118.10 ? 3   ASP A N   1 
ATOM 15   C CA  . ASP A 1 3   ? 143.497 118.911 111.896 1.00 120.36 ? 3   ASP A CA  1 
ATOM 16   C C   . ASP A 1 3   ? 143.354 117.893 110.767 1.00 122.52 ? 3   ASP A C   1 
ATOM 17   O O   . ASP A 1 3   ? 143.107 116.705 110.989 1.00 120.81 ? 3   ASP A O   1 
ATOM 18   C CB  . ASP A 1 3   ? 144.821 119.666 111.788 1.00 122.36 ? 3   ASP A CB  1 
ATOM 19   C CG  . ASP A 1 3   ? 144.862 120.897 112.670 1.00 126.24 ? 3   ASP A CG  1 
ATOM 20   O OD1 . ASP A 1 3   ? 143.790 121.327 113.142 1.00 124.73 ? 3   ASP A OD1 1 
ATOM 21   O OD2 . ASP A 1 3   ? 145.968 121.432 112.894 1.00 125.69 ? 3   ASP A OD2 1 
ATOM 22   N N   . THR A 1 4   ? 143.501 118.373 109.530 1.00 123.71 ? 4   THR A N   1 
ATOM 23   C CA  . THR A 1 4   ? 143.420 117.483 108.377 1.00 124.40 ? 4   THR A CA  1 
ATOM 24   C C   . THR A 1 4   ? 144.537 116.450 108.398 1.00 126.73 ? 4   THR A C   1 
ATOM 25   O O   . THR A 1 4   ? 144.313 115.277 108.080 1.00 126.25 ? 4   THR A O   1 
ATOM 26   C CB  . THR A 1 4   ? 143.473 118.289 107.079 1.00 122.06 ? 4   THR A CB  1 
ATOM 27   O OG1 . THR A 1 4   ? 144.593 119.182 107.113 1.00 126.14 ? 4   THR A OG1 1 
ATOM 28   C CG2 . THR A 1 4   ? 142.198 119.088 106.889 1.00 115.46 ? 4   THR A CG2 1 
ATOM 29   N N   . ASN A 1 5   ? 145.749 116.869 108.767 1.00 126.94 ? 5   ASN A N   1 
ATOM 30   C CA  . ASN A 1 5   ? 146.891 115.961 108.738 1.00 127.25 ? 5   ASN A CA  1 
ATOM 31   C C   . ASN A 1 5   ? 146.687 114.785 109.683 1.00 129.84 ? 5   ASN A C   1 
ATOM 32   O O   . ASN A 1 5   ? 146.942 113.631 109.321 1.00 132.64 ? 5   ASN A O   1 
ATOM 33   C CB  . ASN A 1 5   ? 148.167 116.722 109.096 1.00 125.17 ? 5   ASN A CB  1 
ATOM 34   C CG  . ASN A 1 5   ? 148.300 118.025 108.336 1.00 123.44 ? 5   ASN A CG  1 
ATOM 35   O OD1 . ASN A 1 5   ? 148.830 118.058 107.226 1.00 121.42 ? 5   ASN A OD1 1 
ATOM 36   N ND2 . ASN A 1 5   ? 147.818 119.109 108.933 1.00 122.66 ? 5   ASN A ND2 1 
ATOM 37   N N   . TYR A 1 6   ? 146.211 115.060 110.899 1.00 128.46 ? 6   TYR A N   1 
ATOM 38   C CA  . TYR A 1 6   ? 146.057 114.006 111.898 1.00 128.26 ? 6   TYR A CA  1 
ATOM 39   C C   . TYR A 1 6   ? 145.060 112.950 111.434 1.00 130.53 ? 6   TYR A C   1 
ATOM 40   O O   . TYR A 1 6   ? 145.360 111.751 111.439 1.00 130.71 ? 6   TYR A O   1 
ATOM 41   C CB  . TYR A 1 6   ? 145.618 114.623 113.228 1.00 126.76 ? 6   TYR A CB  1 
ATOM 42   C CG  . TYR A 1 6   ? 145.835 113.756 114.453 1.00 130.63 ? 6   TYR A CG  1 
ATOM 43   C CD1 . TYR A 1 6   ? 146.212 112.424 114.339 1.00 131.67 ? 6   TYR A CD1 1 
ATOM 44   C CD2 . TYR A 1 6   ? 145.658 114.276 115.728 1.00 131.15 ? 6   TYR A CD2 1 
ATOM 45   C CE1 . TYR A 1 6   ? 146.407 111.637 115.457 1.00 137.65 ? 6   TYR A CE1 1 
ATOM 46   C CE2 . TYR A 1 6   ? 145.851 113.498 116.852 1.00 134.11 ? 6   TYR A CE2 1 
ATOM 47   C CZ  . TYR A 1 6   ? 146.225 112.179 116.711 1.00 139.90 ? 6   TYR A CZ  1 
ATOM 48   O OH  . TYR A 1 6   ? 146.418 111.398 117.827 1.00 141.54 ? 6   TYR A OH  1 
ATOM 49   N N   . CYS A 1 7   ? 143.867 113.380 111.020 1.00 130.29 ? 7   CYS A N   1 
ATOM 50   C CA  . CYS A 1 7   ? 142.828 112.423 110.654 1.00 130.43 ? 7   CYS A CA  1 
ATOM 51   C C   . CYS A 1 7   ? 143.138 111.740 109.328 1.00 132.29 ? 7   CYS A C   1 
ATOM 52   O O   . CYS A 1 7   ? 142.841 110.553 109.152 1.00 135.64 ? 7   CYS A O   1 
ATOM 53   C CB  . CYS A 1 7   ? 141.472 113.122 110.601 1.00 124.68 ? 7   CYS A CB  1 
ATOM 54   S SG  . CYS A 1 7   ? 141.009 113.925 112.150 1.00 129.98 ? 7   CYS A SG  1 
ATOM 55   N N   . PHE A 1 8   ? 143.730 112.469 108.380 1.00 130.00 ? 8   PHE A N   1 
ATOM 56   C CA  . PHE A 1 8   ? 144.075 111.869 107.098 1.00 133.11 ? 8   PHE A CA  1 
ATOM 57   C C   . PHE A 1 8   ? 145.266 110.928 107.204 1.00 135.35 ? 8   PHE A C   1 
ATOM 58   O O   . PHE A 1 8   ? 145.432 110.060 106.339 1.00 135.64 ? 8   PHE A O   1 
ATOM 59   C CB  . PHE A 1 8   ? 144.362 112.961 106.065 1.00 131.60 ? 8   PHE A CB  1 
ATOM 60   C CG  . PHE A 1 8   ? 143.154 113.774 105.683 1.00 129.04 ? 8   PHE A CG  1 
ATOM 61   C CD1 . PHE A 1 8   ? 141.876 113.286 105.898 1.00 124.38 ? 8   PHE A CD1 1 
ATOM 62   C CD2 . PHE A 1 8   ? 143.298 115.024 105.106 1.00 124.79 ? 8   PHE A CD2 1 
ATOM 63   C CE1 . PHE A 1 8   ? 140.767 114.031 105.546 1.00 115.18 ? 8   PHE A CE1 1 
ATOM 64   C CE2 . PHE A 1 8   ? 142.191 115.773 104.754 1.00 118.59 ? 8   PHE A CE2 1 
ATOM 65   C CZ  . PHE A 1 8   ? 140.925 115.275 104.974 1.00 114.81 ? 8   PHE A CZ  1 
ATOM 66   N N   . SER A 1 9   ? 146.097 111.079 108.238 1.00 135.30 ? 9   SER A N   1 
ATOM 67   C CA  . SER A 1 9   ? 147.260 110.212 108.386 1.00 136.76 ? 9   SER A CA  1 
ATOM 68   C C   . SER A 1 9   ? 146.863 108.769 108.668 1.00 138.28 ? 9   SER A C   1 
ATOM 69   O O   . SER A 1 9   ? 147.460 107.843 108.107 1.00 140.15 ? 9   SER A O   1 
ATOM 70   C CB  . SER A 1 9   ? 148.166 110.739 109.498 1.00 135.61 ? 9   SER A CB  1 
ATOM 71   O OG  . SER A 1 9   ? 149.282 109.889 109.694 1.00 138.97 ? 9   SER A OG  1 
ATOM 72   N N   . SER A 1 10  ? 145.869 108.554 109.523 1.00 137.10 ? 10  SER A N   1 
ATOM 73   C CA  . SER A 1 10  ? 145.454 107.208 109.906 1.00 137.03 ? 10  SER A CA  1 
ATOM 74   C C   . SER A 1 10  ? 144.020 107.280 110.417 1.00 135.28 ? 10  SER A C   1 
ATOM 75   O O   . SER A 1 10  ? 143.500 108.358 110.720 1.00 135.26 ? 10  SER A O   1 
ATOM 76   C CB  . SER A 1 10  ? 146.391 106.611 110.958 1.00 136.75 ? 10  SER A CB  1 
ATOM 77   O OG  . SER A 1 10  ? 147.712 106.487 110.460 1.00 138.74 ? 10  SER A OG  1 
ATOM 78   N N   . THR A 1 11  ? 143.387 106.114 110.512 1.00 134.15 ? 11  THR A N   1 
ATOM 79   C CA  . THR A 1 11  ? 142.016 106.038 110.994 1.00 131.21 ? 11  THR A CA  1 
ATOM 80   C C   . THR A 1 11  ? 141.941 106.449 112.459 1.00 127.39 ? 11  THR A C   1 
ATOM 81   O O   . THR A 1 11  ? 142.795 106.080 113.270 1.00 127.39 ? 11  THR A O   1 
ATOM 82   C CB  . THR A 1 11  ? 141.471 104.619 110.819 1.00 129.39 ? 11  THR A CB  1 
ATOM 83   O OG1 . THR A 1 11  ? 141.595 104.224 109.448 1.00 132.19 ? 11  THR A OG1 1 
ATOM 84   C CG2 . THR A 1 11  ? 140.006 104.547 111.229 1.00 123.67 ? 11  THR A CG2 1 
ATOM 85   N N   . GLU A 1 12  ? 140.909 107.224 112.796 1.00 124.17 ? 12  GLU A N   1 
ATOM 86   C CA  . GLU A 1 12  ? 140.685 107.654 114.175 1.00 119.67 ? 12  GLU A CA  1 
ATOM 87   C C   . GLU A 1 12  ? 139.184 107.552 114.431 1.00 115.57 ? 12  GLU A C   1 
ATOM 88   O O   . GLU A 1 12  ? 138.400 108.302 113.842 1.00 116.40 ? 12  GLU A O   1 
ATOM 89   C CB  . GLU A 1 12  ? 141.208 109.065 114.404 1.00 120.47 ? 12  GLU A CB  1 
ATOM 90   C CG  . GLU A 1 12  ? 141.840 109.280 115.770 1.00 120.64 ? 12  GLU A CG  1 
ATOM 91   C CD  . GLU A 1 12  ? 142.864 110.400 115.767 1.00 125.54 ? 12  GLU A CD  1 
ATOM 92   O OE1 . GLU A 1 12  ? 142.960 111.118 114.750 1.00 127.31 ? 12  GLU A OE1 1 
ATOM 93   O OE2 . GLU A 1 12  ? 143.580 110.557 116.778 1.00 123.53 ? 12  GLU A OE2 1 
ATOM 94   N N   . LYS A 1 13  ? 138.797 106.621 115.305 1.00 113.32 ? 13  LYS A N   1 
ATOM 95   C CA  . LYS A 1 13  ? 137.383 106.306 115.482 1.00 113.42 ? 13  LYS A CA  1 
ATOM 96   C C   . LYS A 1 13  ? 136.602 107.484 116.050 1.00 110.26 ? 13  LYS A C   1 
ATOM 97   O O   . LYS A 1 13  ? 135.414 107.641 115.749 1.00 108.22 ? 13  LYS A O   1 
ATOM 98   C CB  . LYS A 1 13  ? 137.233 105.084 116.387 1.00 114.01 ? 13  LYS A CB  1 
ATOM 99   C CG  . LYS A 1 13  ? 135.865 104.431 116.324 1.00 119.74 ? 13  LYS A CG  1 
ATOM 100  C CD  . LYS A 1 13  ? 135.591 103.880 114.935 1.00 122.34 ? 13  LYS A CD  1 
ATOM 101  C CE  . LYS A 1 13  ? 134.245 103.178 114.873 1.00 124.04 ? 13  LYS A CE  1 
ATOM 102  N NZ  . LYS A 1 13  ? 134.167 102.048 115.837 1.00 128.58 ? 13  LYS A NZ  1 
ATOM 103  N N   . ASN A 1 14  ? 137.243 108.318 116.864 1.00 107.96 ? 14  ASN A N   1 
ATOM 104  C CA  . ASN A 1 14  ? 136.559 109.429 117.505 1.00 100.14 ? 14  ASN A CA  1 
ATOM 105  C C   . ASN A 1 14  ? 136.367 110.585 116.530 1.00 100.94 ? 14  ASN A C   1 
ATOM 106  O O   . ASN A 1 14  ? 136.591 110.462 115.323 1.00 105.76 ? 14  ASN A O   1 
ATOM 107  C CB  . ASN A 1 14  ? 137.337 109.901 118.731 1.00 99.36  ? 14  ASN A CB  1 
ATOM 108  C CG  . ASN A 1 14  ? 137.274 108.912 119.873 1.00 102.69 ? 14  ASN A CG  1 
ATOM 109  O OD1 . ASN A 1 14  ? 136.356 108.097 119.952 1.00 106.65 ? 14  ASN A OD1 1 
ATOM 110  N ND2 . ASN A 1 14  ? 138.253 108.976 120.766 1.00 101.84 ? 14  ASN A ND2 1 
ATOM 111  N N   . CYS A 1 15  ? 135.930 111.720 117.077 1.00 95.59  ? 15  CYS A N   1 
ATOM 112  C CA  . CYS A 1 15  ? 135.675 112.927 116.298 1.00 96.71  ? 15  CYS A CA  1 
ATOM 113  C C   . CYS A 1 15  ? 136.869 113.293 115.429 1.00 100.19 ? 15  CYS A C   1 
ATOM 114  O O   . CYS A 1 15  ? 137.951 113.600 115.937 1.00 102.12 ? 15  CYS A O   1 
ATOM 115  C CB  . CYS A 1 15  ? 135.317 114.086 117.230 1.00 90.34  ? 15  CYS A CB  1 
ATOM 116  S SG  . CYS A 1 15  ? 135.338 115.751 116.513 1.00 81.83  ? 15  CYS A SG  1 
ATOM 117  N N   . CYS A 1 16  ? 136.674 113.262 114.116 1.00 99.29  ? 16  CYS A N   1 
ATOM 118  C CA  . CYS A 1 16  ? 137.743 113.555 113.180 1.00 97.29  ? 16  CYS A CA  1 
ATOM 119  C C   . CYS A 1 16  ? 137.140 114.136 111.912 1.00 97.97  ? 16  CYS A C   1 
ATOM 120  O O   . CYS A 1 16  ? 135.952 113.961 111.624 1.00 96.49  ? 16  CYS A O   1 
ATOM 121  C CB  . CYS A 1 16  ? 138.565 112.304 112.856 1.00 103.41 ? 16  CYS A CB  1 
ATOM 122  S SG  . CYS A 1 16  ? 140.303 112.418 113.312 1.00 129.38 ? 16  CYS A SG  1 
ATOM 123  N N   . VAL A 1 17  ? 137.978 114.837 111.162 1.00 97.90  ? 17  VAL A N   1 
ATOM 124  C CA  . VAL A 1 17  ? 137.591 115.395 109.875 1.00 95.08  ? 17  VAL A CA  1 
ATOM 125  C C   . VAL A 1 17  ? 137.813 114.336 108.808 1.00 96.76  ? 17  VAL A C   1 
ATOM 126  O O   . VAL A 1 17  ? 138.925 113.819 108.654 1.00 103.60 ? 17  VAL A O   1 
ATOM 127  C CB  . VAL A 1 17  ? 138.386 116.675 109.571 1.00 96.72  ? 17  VAL A CB  1 
ATOM 128  C CG1 . VAL A 1 17  ? 139.861 116.365 109.460 1.00 103.18 ? 17  VAL A CG1 1 
ATOM 129  C CG2 . VAL A 1 17  ? 137.890 117.315 108.303 1.00 101.12 ? 17  VAL A CG2 1 
ATOM 130  N N   . ARG A 1 18  ? 136.758 114.002 108.078 1.00 99.13  ? 18  ARG A N   1 
ATOM 131  C CA  . ARG A 1 18  ? 136.791 112.955 107.072 1.00 99.11  ? 18  ARG A CA  1 
ATOM 132  C C   . ARG A 1 18  ? 136.647 113.580 105.693 1.00 102.19 ? 18  ARG A C   1 
ATOM 133  O O   . ARG A 1 18  ? 135.886 114.538 105.509 1.00 103.76 ? 18  ARG A O   1 
ATOM 134  C CB  . ARG A 1 18  ? 135.676 111.935 107.310 1.00 99.93  ? 18  ARG A CB  1 
ATOM 135  C CG  . ARG A 1 18  ? 135.209 111.859 108.755 1.00 100.54 ? 18  ARG A CG  1 
ATOM 136  C CD  . ARG A 1 18  ? 136.268 111.270 109.667 1.00 100.11 ? 18  ARG A CD  1 
ATOM 137  N NE  . ARG A 1 18  ? 136.297 109.816 109.590 1.00 108.16 ? 18  ARG A NE  1 
ATOM 138  C CZ  . ARG A 1 18  ? 135.558 109.014 110.343 1.00 113.76 ? 18  ARG A CZ  1 
ATOM 139  N NH1 . ARG A 1 18  ? 134.722 109.494 111.249 1.00 104.63 ? 18  ARG A NH1 1 
ATOM 140  N NH2 . ARG A 1 18  ? 135.660 107.698 110.184 1.00 124.24 ? 18  ARG A NH2 1 
ATOM 141  N N   . GLN A 1 19  ? 137.391 113.038 104.733 1.00 104.50 ? 19  GLN A N   1 
ATOM 142  C CA  . GLN A 1 19  ? 137.392 113.577 103.382 1.00 107.83 ? 19  GLN A CA  1 
ATOM 143  C C   . GLN A 1 19  ? 136.024 113.408 102.735 1.00 108.25 ? 19  GLN A C   1 
ATOM 144  O O   . GLN A 1 19  ? 135.371 112.371 102.881 1.00 105.03 ? 19  GLN A O   1 
ATOM 145  C CB  . GLN A 1 19  ? 138.465 112.881 102.546 1.00 105.60 ? 19  GLN A CB  1 
ATOM 146  C CG  . GLN A 1 19  ? 138.682 113.484 101.174 1.00 112.38 ? 19  GLN A CG  1 
ATOM 147  C CD  . GLN A 1 19  ? 139.781 112.782 100.404 1.00 124.01 ? 19  GLN A CD  1 
ATOM 148  O OE1 . GLN A 1 19  ? 140.138 113.188 99.298  1.00 130.76 ? 19  GLN A OE1 1 
ATOM 149  N NE2 . GLN A 1 19  ? 140.324 111.719 100.986 1.00 125.93 ? 19  GLN A NE2 1 
ATOM 150  N N   . LEU A 1 20  ? 135.588 114.443 102.019 1.00 108.39 ? 20  LEU A N   1 
ATOM 151  C CA  . LEU A 1 20  ? 134.317 114.414 101.312 1.00 106.27 ? 20  LEU A CA  1 
ATOM 152  C C   . LEU A 1 20  ? 134.387 115.366 100.129 1.00 109.89 ? 20  LEU A C   1 
ATOM 153  O O   . LEU A 1 20  ? 134.855 116.498 100.263 1.00 110.00 ? 20  LEU A O   1 
ATOM 154  C CB  . LEU A 1 20  ? 133.155 114.799 102.228 1.00 103.81 ? 20  LEU A CB  1 
ATOM 155  C CG  . LEU A 1 20  ? 131.790 114.929 101.557 1.00 109.37 ? 20  LEU A CG  1 
ATOM 156  C CD1 . LEU A 1 20  ? 131.323 113.584 101.022 1.00 112.26 ? 20  LEU A CD1 1 
ATOM 157  C CD2 . LEU A 1 20  ? 130.775 115.512 102.525 1.00 109.60 ? 20  LEU A CD2 1 
ATOM 158  N N   . TYR A 1 21  ? 133.909 114.902 98.978  1.00 114.68 ? 21  TYR A N   1 
ATOM 159  C CA  . TYR A 1 21  ? 133.952 115.663 97.737  1.00 117.94 ? 21  TYR A CA  1 
ATOM 160  C C   . TYR A 1 21  ? 132.561 116.189 97.421  1.00 117.91 ? 21  TYR A C   1 
ATOM 161  O O   . TYR A 1 21  ? 131.609 115.410 97.306  1.00 122.10 ? 21  TYR A O   1 
ATOM 162  C CB  . TYR A 1 21  ? 134.468 114.798 96.584  1.00 120.45 ? 21  TYR A CB  1 
ATOM 163  C CG  . TYR A 1 21  ? 134.453 115.487 95.238  1.00 122.16 ? 21  TYR A CG  1 
ATOM 164  C CD1 . TYR A 1 21  ? 135.493 116.321 94.852  1.00 124.01 ? 21  TYR A CD1 1 
ATOM 165  C CD2 . TYR A 1 21  ? 133.404 115.295 94.350  1.00 121.01 ? 21  TYR A CD2 1 
ATOM 166  C CE1 . TYR A 1 21  ? 135.484 116.952 93.625  1.00 127.32 ? 21  TYR A CE1 1 
ATOM 167  C CE2 . TYR A 1 21  ? 133.387 115.921 93.120  1.00 122.94 ? 21  TYR A CE2 1 
ATOM 168  C CZ  . TYR A 1 21  ? 134.429 116.748 92.763  1.00 127.02 ? 21  TYR A CZ  1 
ATOM 169  O OH  . TYR A 1 21  ? 134.417 117.373 91.538  1.00 129.45 ? 21  TYR A OH  1 
ATOM 170  N N   . ILE A 1 22  ? 132.449 117.504 97.276  1.00 117.18 ? 22  ILE A N   1 
ATOM 171  C CA  . ILE A 1 22  ? 131.194 118.165 96.943  1.00 119.16 ? 22  ILE A CA  1 
ATOM 172  C C   . ILE A 1 22  ? 131.280 118.632 95.499  1.00 122.41 ? 22  ILE A C   1 
ATOM 173  O O   . ILE A 1 22  ? 132.139 119.454 95.153  1.00 124.19 ? 22  ILE A O   1 
ATOM 174  C CB  . ILE A 1 22  ? 130.906 119.343 97.887  1.00 113.77 ? 22  ILE A CB  1 
ATOM 175  C CG1 . ILE A 1 22  ? 130.477 118.833 99.260  1.00 111.67 ? 22  ILE A CG1 1 
ATOM 176  C CG2 . ILE A 1 22  ? 129.842 120.254 97.305  1.00 110.61 ? 22  ILE A CG2 1 
ATOM 177  C CD1 . ILE A 1 22  ? 129.179 118.094 99.245  1.00 107.00 ? 22  ILE A CD1 1 
ATOM 178  N N   . ASP A 1 23  ? 130.400 118.100 94.655  1.00 121.22 ? 23  ASP A N   1 
ATOM 179  C CA  . ASP A 1 23  ? 130.252 118.548 93.278  1.00 118.80 ? 23  ASP A CA  1 
ATOM 180  C C   . ASP A 1 23  ? 129.045 119.471 93.223  1.00 114.77 ? 23  ASP A C   1 
ATOM 181  O O   . ASP A 1 23  ? 127.930 119.050 93.544  1.00 115.30 ? 23  ASP A O   1 
ATOM 182  C CB  . ASP A 1 23  ? 130.075 117.360 92.332  1.00 121.96 ? 23  ASP A CB  1 
ATOM 183  C CG  . ASP A 1 23  ? 130.018 117.776 90.875  1.00 124.63 ? 23  ASP A CG  1 
ATOM 184  O OD1 . ASP A 1 23  ? 131.089 118.028 90.286  1.00 128.61 ? 23  ASP A OD1 1 
ATOM 185  O OD2 . ASP A 1 23  ? 128.903 117.848 90.318  1.00 121.33 ? 23  ASP A OD2 1 
ATOM 186  N N   . PHE A 1 24  ? 129.267 120.722 92.819  1.00 112.30 ? 24  PHE A N   1 
ATOM 187  C CA  . PHE A 1 24  ? 128.230 121.739 92.958  1.00 112.95 ? 24  PHE A CA  1 
ATOM 188  C C   . PHE A 1 24  ? 126.952 121.345 92.227  1.00 114.47 ? 24  PHE A C   1 
ATOM 189  O O   . PHE A 1 24  ? 125.874 121.297 92.830  1.00 116.02 ? 24  PHE A O   1 
ATOM 190  C CB  . PHE A 1 24  ? 128.747 123.081 92.451  1.00 113.60 ? 24  PHE A CB  1 
ATOM 191  C CG  . PHE A 1 24  ? 129.745 123.722 93.360  1.00 117.68 ? 24  PHE A CG  1 
ATOM 192  C CD1 . PHE A 1 24  ? 129.338 124.617 94.329  1.00 119.63 ? 24  PHE A CD1 1 
ATOM 193  C CD2 . PHE A 1 24  ? 131.088 123.428 93.251  1.00 122.44 ? 24  PHE A CD2 1 
ATOM 194  C CE1 . PHE A 1 24  ? 130.252 125.208 95.170  1.00 121.40 ? 24  PHE A CE1 1 
ATOM 195  C CE2 . PHE A 1 24  ? 132.007 124.018 94.089  1.00 125.43 ? 24  PHE A CE2 1 
ATOM 196  C CZ  . PHE A 1 24  ? 131.586 124.910 95.049  1.00 124.09 ? 24  PHE A CZ  1 
ATOM 197  N N   . ARG A 1 25  ? 127.057 121.018 90.939  1.00 112.33 ? 25  ARG A N   1 
ATOM 198  C CA  . ARG A 1 25  ? 125.858 120.725 90.160  1.00 112.33 ? 25  ARG A CA  1 
ATOM 199  C C   . ARG A 1 25  ? 125.160 119.467 90.664  1.00 112.74 ? 25  ARG A C   1 
ATOM 200  O O   . ARG A 1 25  ? 123.939 119.455 90.854  1.00 114.36 ? 25  ARG A O   1 
ATOM 201  C CB  . ARG A 1 25  ? 126.210 120.592 88.678  1.00 113.97 ? 25  ARG A CB  1 
ATOM 202  C CG  . ARG A 1 25  ? 125.060 120.090 87.818  1.00 116.23 ? 25  ARG A CG  1 
ATOM 203  C CD  . ARG A 1 25  ? 125.307 120.332 86.337  1.00 119.64 ? 25  ARG A CD  1 
ATOM 204  N NE  . ARG A 1 25  ? 125.077 121.722 85.961  1.00 122.10 ? 25  ARG A NE  1 
ATOM 205  C CZ  . ARG A 1 25  ? 126.032 122.633 85.831  1.00 121.73 ? 25  ARG A CZ  1 
ATOM 206  N NH1 . ARG A 1 25  ? 127.305 122.334 86.031  1.00 122.84 ? 25  ARG A NH1 1 
ATOM 207  N NH2 . ARG A 1 25  ? 125.701 123.875 85.489  1.00 118.74 ? 25  ARG A NH2 1 
ATOM 208  N N   . LYS A 1 26  ? 125.921 118.397 90.895  1.00 114.20 ? 26  LYS A N   1 
ATOM 209  C CA  . LYS A 1 26  ? 125.300 117.134 91.283  1.00 113.20 ? 26  LYS A CA  1 
ATOM 210  C C   . LYS A 1 26  ? 124.828 117.159 92.731  1.00 110.14 ? 26  LYS A C   1 
ATOM 211  O O   . LYS A 1 26  ? 123.755 116.631 93.046  1.00 106.86 ? 26  LYS A O   1 
ATOM 212  C CB  . LYS A 1 26  ? 126.273 115.978 91.059  1.00 117.37 ? 26  LYS A CB  1 
ATOM 213  C CG  . LYS A 1 26  ? 126.605 115.723 89.600  1.00 121.76 ? 26  LYS A CG  1 
ATOM 214  C CD  . LYS A 1 26  ? 127.473 114.487 89.439  1.00 123.22 ? 26  LYS A CD  1 
ATOM 215  C CE  . LYS A 1 26  ? 126.752 113.242 89.930  1.00 126.85 ? 26  LYS A CE  1 
ATOM 216  N NZ  . LYS A 1 26  ? 127.572 112.013 89.740  1.00 134.93 ? 26  LYS A NZ  1 
ATOM 217  N N   . ASP A 1 27  ? 125.608 117.765 93.626  1.00 113.26 ? 27  ASP A N   1 
ATOM 218  C CA  . ASP A 1 27  ? 125.311 117.686 95.052  1.00 112.56 ? 27  ASP A CA  1 
ATOM 219  C C   . ASP A 1 27  ? 124.465 118.853 95.546  1.00 111.67 ? 27  ASP A C   1 
ATOM 220  O O   . ASP A 1 27  ? 123.433 118.638 96.185  1.00 112.38 ? 27  ASP A O   1 
ATOM 221  C CB  . ASP A 1 27  ? 126.608 117.610 95.861  1.00 112.47 ? 27  ASP A CB  1 
ATOM 222  C CG  . ASP A 1 27  ? 127.381 116.340 95.599  1.00 116.84 ? 27  ASP A CG  1 
ATOM 223  O OD1 . ASP A 1 27  ? 126.808 115.246 95.785  1.00 120.75 ? 27  ASP A OD1 1 
ATOM 224  O OD2 . ASP A 1 27  ? 128.560 116.434 95.199  1.00 119.16 ? 27  ASP A OD2 1 
ATOM 225  N N   . LEU A 1 28  ? 124.884 120.088 95.278  1.00 108.20 ? 28  LEU A N   1 
ATOM 226  C CA  . LEU A 1 28  ? 124.209 121.251 95.827  1.00 105.99 ? 28  LEU A CA  1 
ATOM 227  C C   . LEU A 1 28  ? 123.234 121.901 94.860  1.00 106.64 ? 28  LEU A C   1 
ATOM 228  O O   . LEU A 1 28  ? 122.427 122.731 95.287  1.00 107.70 ? 28  LEU A O   1 
ATOM 229  C CB  . LEU A 1 28  ? 125.239 122.296 96.277  1.00 103.47 ? 28  LEU A CB  1 
ATOM 230  C CG  . LEU A 1 28  ? 126.328 121.801 97.224  1.00 97.87  ? 28  LEU A CG  1 
ATOM 231  C CD1 . LEU A 1 28  ? 127.229 122.946 97.628  1.00 101.44 ? 28  LEU A CD1 1 
ATOM 232  C CD2 . LEU A 1 28  ? 125.718 121.148 98.444  1.00 100.93 ? 28  LEU A CD2 1 
ATOM 233  N N   . GLY A 1 29  ? 123.285 121.554 93.578  1.00 108.68 ? 29  GLY A N   1 
ATOM 234  C CA  . GLY A 1 29  ? 122.435 122.210 92.610  1.00 110.19 ? 29  GLY A CA  1 
ATOM 235  C C   . GLY A 1 29  ? 122.894 123.589 92.206  1.00 112.73 ? 29  GLY A C   1 
ATOM 236  O O   . GLY A 1 29  ? 122.195 124.260 91.442  1.00 116.31 ? 29  GLY A O   1 
ATOM 237  N N   . TRP A 1 30  ? 124.052 124.032 92.688  1.00 110.68 ? 30  TRP A N   1 
ATOM 238  C CA  . TRP A 1 30  ? 124.574 125.356 92.364  1.00 113.70 ? 30  TRP A CA  1 
ATOM 239  C C   . TRP A 1 30  ? 125.108 125.319 90.941  1.00 118.64 ? 30  TRP A C   1 
ATOM 240  O O   . TRP A 1 30  ? 126.302 125.142 90.702  1.00 121.85 ? 30  TRP A O   1 
ATOM 241  C CB  . TRP A 1 30  ? 125.657 125.770 93.351  1.00 114.37 ? 30  TRP A CB  1 
ATOM 242  C CG  . TRP A 1 30  ? 125.160 126.042 94.731  1.00 111.44 ? 30  TRP A CG  1 
ATOM 243  C CD1 . TRP A 1 30  ? 123.920 125.776 95.223  1.00 110.22 ? 30  TRP A CD1 1 
ATOM 244  C CD2 . TRP A 1 30  ? 125.896 126.643 95.800  1.00 111.70 ? 30  TRP A CD2 1 
ATOM 245  N NE1 . TRP A 1 30  ? 123.836 126.171 96.534  1.00 111.81 ? 30  TRP A NE1 1 
ATOM 246  C CE2 . TRP A 1 30  ? 125.038 126.707 96.912  1.00 113.75 ? 30  TRP A CE2 1 
ATOM 247  C CE3 . TRP A 1 30  ? 127.198 127.131 95.926  1.00 112.79 ? 30  TRP A CE3 1 
ATOM 248  C CZ2 . TRP A 1 30  ? 125.439 127.241 98.132  1.00 115.79 ? 30  TRP A CZ2 1 
ATOM 249  C CZ3 . TRP A 1 30  ? 127.594 127.660 97.137  1.00 115.72 ? 30  TRP A CZ3 1 
ATOM 250  C CH2 . TRP A 1 30  ? 126.718 127.711 98.224  1.00 115.24 ? 30  TRP A CH2 1 
ATOM 251  N N   . LYS A 1 31  ? 124.209 125.498 89.979  1.00 121.45 ? 31  LYS A N   1 
ATOM 252  C CA  . LYS A 1 31  ? 124.573 125.532 88.572  1.00 123.40 ? 31  LYS A CA  1 
ATOM 253  C C   . LYS A 1 31  ? 125.114 126.890 88.155  1.00 127.16 ? 31  LYS A C   1 
ATOM 254  O O   . LYS A 1 31  ? 125.445 127.083 86.981  1.00 128.72 ? 31  LYS A O   1 
ATOM 255  C CB  . LYS A 1 31  ? 123.369 125.149 87.710  1.00 122.24 ? 31  LYS A CB  1 
ATOM 256  C CG  . LYS A 1 31  ? 122.079 125.836 88.123  1.00 122.92 ? 31  LYS A CG  1 
ATOM 257  C CD  . LYS A 1 31  ? 120.895 125.347 87.305  1.00 126.14 ? 31  LYS A CD  1 
ATOM 258  C CE  . LYS A 1 31  ? 119.615 126.063 87.711  1.00 124.56 ? 31  LYS A CE  1 
ATOM 259  N NZ  . LYS A 1 31  ? 118.437 125.596 86.930  1.00 122.18 ? 31  LYS A NZ  1 
ATOM 260  N N   . TRP A 1 32  ? 125.209 127.832 89.090  1.00 127.16 ? 32  TRP A N   1 
ATOM 261  C CA  . TRP A 1 32  ? 125.701 129.170 88.799  1.00 131.67 ? 32  TRP A CA  1 
ATOM 262  C C   . TRP A 1 32  ? 127.210 129.300 88.939  1.00 135.50 ? 32  TRP A C   1 
ATOM 263  O O   . TRP A 1 32  ? 127.760 130.355 88.602  1.00 140.29 ? 32  TRP A O   1 
ATOM 264  C CB  . TRP A 1 32  ? 125.024 130.186 89.721  1.00 128.33 ? 32  TRP A CB  1 
ATOM 265  C CG  . TRP A 1 32  ? 125.320 129.953 91.164  1.00 128.33 ? 32  TRP A CG  1 
ATOM 266  C CD1 . TRP A 1 32  ? 124.697 129.072 91.997  1.00 127.31 ? 32  TRP A CD1 1 
ATOM 267  C CD2 . TRP A 1 32  ? 126.317 130.613 91.950  1.00 132.35 ? 32  TRP A CD2 1 
ATOM 268  N NE1 . TRP A 1 32  ? 125.243 129.142 93.254  1.00 128.34 ? 32  TRP A NE1 1 
ATOM 269  C CE2 . TRP A 1 32  ? 126.240 130.082 93.251  1.00 131.48 ? 32  TRP A CE2 1 
ATOM 270  C CE3 . TRP A 1 32  ? 127.266 131.602 91.679  1.00 135.18 ? 32  TRP A CE3 1 
ATOM 271  C CZ2 . TRP A 1 32  ? 127.077 130.506 94.279  1.00 132.63 ? 32  TRP A CZ2 1 
ATOM 272  C CZ3 . TRP A 1 32  ? 128.095 132.022 92.700  1.00 137.05 ? 32  TRP A CZ3 1 
ATOM 273  C CH2 . TRP A 1 32  ? 127.995 131.475 93.985  1.00 135.26 ? 32  TRP A CH2 1 
ATOM 274  N N   . ILE A 1 33  ? 127.891 128.266 89.424  1.00 134.44 ? 33  ILE A N   1 
ATOM 275  C CA  . ILE A 1 33  ? 129.336 128.293 89.613  1.00 137.95 ? 33  ILE A CA  1 
ATOM 276  C C   . ILE A 1 33  ? 129.992 127.537 88.469  1.00 142.84 ? 33  ILE A C   1 
ATOM 277  O O   . ILE A 1 33  ? 129.684 126.363 88.231  1.00 144.37 ? 33  ILE A O   1 
ATOM 278  C CB  . ILE A 1 33  ? 129.732 127.694 90.972  1.00 131.77 ? 33  ILE A CB  1 
ATOM 279  C CG1 . ILE A 1 33  ? 129.371 128.665 92.097  1.00 130.60 ? 33  ILE A CG1 1 
ATOM 280  C CG2 . ILE A 1 33  ? 131.212 127.367 90.999  1.00 135.58 ? 33  ILE A CG2 1 
ATOM 281  C CD1 . ILE A 1 33  ? 129.851 128.229 93.458  1.00 130.90 ? 33  ILE A CD1 1 
ATOM 282  N N   . HIS A 1 34  ? 130.899 128.211 87.758  1.00 147.58 ? 34  HIS A N   1 
ATOM 283  C CA  . HIS A 1 34  ? 131.570 127.590 86.622  1.00 150.10 ? 34  HIS A CA  1 
ATOM 284  C C   . HIS A 1 34  ? 132.808 126.816 87.059  1.00 150.59 ? 34  HIS A C   1 
ATOM 285  O O   . HIS A 1 34  ? 132.942 125.625 86.759  1.00 147.08 ? 34  HIS A O   1 
ATOM 286  C CB  . HIS A 1 34  ? 131.942 128.651 85.587  1.00 152.64 ? 34  HIS A CB  1 
ATOM 287  C CG  . HIS A 1 34  ? 132.745 128.120 84.443  1.00 155.17 ? 34  HIS A CG  1 
ATOM 288  N ND1 . HIS A 1 34  ? 134.104 128.317 84.335  1.00 159.44 ? 34  HIS A ND1 1 
ATOM 289  C CD2 . HIS A 1 34  ? 132.382 127.396 83.359  1.00 157.16 ? 34  HIS A CD2 1 
ATOM 290  C CE1 . HIS A 1 34  ? 134.544 127.739 83.232  1.00 163.57 ? 34  HIS A CE1 1 
ATOM 291  N NE2 . HIS A 1 34  ? 133.519 127.173 82.621  1.00 164.70 ? 34  HIS A NE2 1 
ATOM 292  N N   . GLU A 1 35  ? 133.725 127.479 87.761  1.00 153.29 ? 35  GLU A N   1 
ATOM 293  C CA  . GLU A 1 35  ? 134.930 126.837 88.263  1.00 154.95 ? 35  GLU A CA  1 
ATOM 294  C C   . GLU A 1 35  ? 135.062 127.127 89.753  1.00 154.74 ? 35  GLU A C   1 
ATOM 295  O O   . GLU A 1 35  ? 134.850 128.273 90.183  1.00 155.00 ? 35  GLU A O   1 
ATOM 296  C CB  . GLU A 1 35  ? 136.178 127.322 87.513  1.00 155.65 ? 35  GLU A CB  1 
ATOM 297  C CG  . GLU A 1 35  ? 136.325 126.750 86.115  1.00 158.81 ? 35  GLU A CG  1 
ATOM 298  C CD  . GLU A 1 35  ? 137.585 127.229 85.421  1.00 165.73 ? 35  GLU A CD  1 
ATOM 299  O OE1 . GLU A 1 35  ? 138.407 127.903 86.077  1.00 166.28 ? 35  GLU A OE1 1 
ATOM 300  O OE2 . GLU A 1 35  ? 137.753 126.932 84.219  1.00 167.86 ? 35  GLU A OE2 1 
ATOM 301  N N   . PRO A 1 36  ? 135.409 126.128 90.571  1.00 151.28 ? 36  PRO A N   1 
ATOM 302  C CA  . PRO A 1 36  ? 135.635 124.723 90.213  1.00 144.57 ? 36  PRO A CA  1 
ATOM 303  C C   . PRO A 1 36  ? 134.328 123.956 90.087  1.00 142.60 ? 36  PRO A C   1 
ATOM 304  O O   . PRO A 1 36  ? 133.364 124.265 90.778  1.00 143.70 ? 36  PRO A O   1 
ATOM 305  C CB  . PRO A 1 36  ? 136.484 124.215 91.379  1.00 139.24 ? 36  PRO A CB  1 
ATOM 306  C CG  . PRO A 1 36  ? 135.965 124.994 92.552  1.00 140.87 ? 36  PRO A CG  1 
ATOM 307  C CD  . PRO A 1 36  ? 135.642 126.366 92.006  1.00 147.21 ? 36  PRO A CD  1 
ATOM 308  N N   . LYS A 1 37  ? 134.261 122.948 89.218  1.00 139.58 ? 37  LYS A N   1 
ATOM 309  C CA  . LYS A 1 37  ? 133.069 122.115 89.136  1.00 136.18 ? 37  LYS A CA  1 
ATOM 310  C C   . LYS A 1 37  ? 132.868 121.265 90.380  1.00 132.81 ? 37  LYS A C   1 
ATOM 311  O O   . LYS A 1 37  ? 131.780 120.710 90.565  1.00 131.57 ? 37  LYS A O   1 
ATOM 312  C CB  . LYS A 1 37  ? 133.137 121.217 87.900  1.00 134.86 ? 37  LYS A CB  1 
ATOM 313  C CG  . LYS A 1 37  ? 134.381 120.351 87.830  1.00 135.64 ? 37  LYS A CG  1 
ATOM 314  C CD  . LYS A 1 37  ? 134.360 119.463 86.598  1.00 138.02 ? 37  LYS A CD  1 
ATOM 315  C CE  . LYS A 1 37  ? 134.196 120.286 85.331  1.00 142.14 ? 37  LYS A CE  1 
ATOM 316  N NZ  . LYS A 1 37  ? 135.282 121.293 85.184  1.00 147.23 ? 37  LYS A NZ  1 
ATOM 317  N N   . GLY A 1 38  ? 133.883 121.155 91.227  1.00 130.84 ? 38  GLY A N   1 
ATOM 318  C CA  . GLY A 1 38  ? 133.759 120.453 92.487  1.00 125.99 ? 38  GLY A CA  1 
ATOM 319  C C   . GLY A 1 38  ? 134.966 120.736 93.348  1.00 126.91 ? 38  GLY A C   1 
ATOM 320  O O   . GLY A 1 38  ? 136.006 121.192 92.861  1.00 129.96 ? 38  GLY A O   1 
ATOM 321  N N   . TYR A 1 39  ? 134.815 120.463 94.639  1.00 124.10 ? 39  TYR A N   1 
ATOM 322  C CA  . TYR A 1 39  ? 135.899 120.695 95.585  1.00 124.03 ? 39  TYR A CA  1 
ATOM 323  C C   . TYR A 1 39  ? 135.789 119.674 96.709  1.00 121.06 ? 39  TYR A C   1 
ATOM 324  O O   . TYR A 1 39  ? 134.954 118.768 96.668  1.00 119.62 ? 39  TYR A O   1 
ATOM 325  C CB  . TYR A 1 39  ? 135.870 122.137 96.105  1.00 125.59 ? 39  TYR A CB  1 
ATOM 326  C CG  . TYR A 1 39  ? 134.840 122.397 97.177  1.00 125.25 ? 39  TYR A CG  1 
ATOM 327  C CD1 . TYR A 1 39  ? 133.483 122.334 96.896  1.00 125.25 ? 39  TYR A CD1 1 
ATOM 328  C CD2 . TYR A 1 39  ? 135.225 122.728 98.468  1.00 123.69 ? 39  TYR A CD2 1 
ATOM 329  C CE1 . TYR A 1 39  ? 132.539 122.581 97.873  1.00 121.25 ? 39  TYR A CE1 1 
ATOM 330  C CE2 . TYR A 1 39  ? 134.290 122.979 99.450  1.00 121.25 ? 39  TYR A CE2 1 
ATOM 331  C CZ  . TYR A 1 39  ? 132.949 122.905 99.147  1.00 118.17 ? 39  TYR A CZ  1 
ATOM 332  O OH  . TYR A 1 39  ? 132.013 123.152 100.122 1.00 113.17 ? 39  TYR A OH  1 
ATOM 333  N N   . HIS A 1 40  ? 136.644 119.820 97.716  1.00 118.35 ? 40  HIS A N   1 
ATOM 334  C CA  . HIS A 1 40  ? 136.692 118.900 98.849  1.00 118.10 ? 40  HIS A CA  1 
ATOM 335  C C   . HIS A 1 40  ? 136.160 119.619 100.082 1.00 120.75 ? 40  HIS A C   1 
ATOM 336  O O   . HIS A 1 40  ? 136.869 120.416 100.703 1.00 123.51 ? 40  HIS A O   1 
ATOM 337  C CB  . HIS A 1 40  ? 138.107 118.379 99.073  1.00 115.41 ? 40  HIS A CB  1 
ATOM 338  C CG  . HIS A 1 40  ? 138.492 117.269 98.148  1.00 118.10 ? 40  HIS A CG  1 
ATOM 339  N ND1 . HIS A 1 40  ? 138.565 117.431 96.782  1.00 121.09 ? 40  HIS A ND1 1 
ATOM 340  C CD2 . HIS A 1 40  ? 138.817 115.977 98.392  1.00 118.73 ? 40  HIS A CD2 1 
ATOM 341  C CE1 . HIS A 1 40  ? 138.922 116.288 96.224  1.00 119.30 ? 40  HIS A CE1 1 
ATOM 342  N NE2 . HIS A 1 40  ? 139.082 115.390 97.179  1.00 120.45 ? 40  HIS A NE2 1 
ATOM 343  N N   . ALA A 1 41  ? 134.909 119.336 100.430 1.00 118.75 ? 41  ALA A N   1 
ATOM 344  C CA  . ALA A 1 41  ? 134.287 119.845 101.646 1.00 116.11 ? 41  ALA A CA  1 
ATOM 345  C C   . ALA A 1 41  ? 134.265 118.703 102.655 1.00 111.89 ? 41  ALA A C   1 
ATOM 346  O O   . ALA A 1 41  ? 133.312 117.927 102.731 1.00 112.86 ? 41  ALA A O   1 
ATOM 347  C CB  . ALA A 1 41  ? 132.892 120.376 101.370 1.00 114.19 ? 41  ALA A CB  1 
ATOM 348  N N   . ASN A 1 42  ? 135.338 118.599 103.429 1.00 104.62 ? 42  ASN A N   1 
ATOM 349  C CA  . ASN A 1 42  ? 135.433 117.554 104.434 1.00 103.21 ? 42  ASN A CA  1 
ATOM 350  C C   . ASN A 1 42  ? 134.386 117.769 105.516 1.00 100.78 ? 42  ASN A C   1 
ATOM 351  O O   . ASN A 1 42  ? 133.959 118.897 105.770 1.00 101.89 ? 42  ASN A O   1 
ATOM 352  C CB  . ASN A 1 42  ? 136.833 117.547 105.039 1.00 103.78 ? 42  ASN A CB  1 
ATOM 353  C CG  . ASN A 1 42  ? 137.913 117.658 103.992 1.00 108.24 ? 42  ASN A CG  1 
ATOM 354  O OD1 . ASN A 1 42  ? 137.739 117.214 102.858 1.00 113.60 ? 42  ASN A OD1 1 
ATOM 355  N ND2 . ASN A 1 42  ? 139.037 118.258 104.361 1.00 112.62 ? 42  ASN A ND2 1 
ATOM 356  N N   . PHE A 1 43  ? 133.956 116.681 106.145 1.00 96.56  ? 43  PHE A N   1 
ATOM 357  C CA  . PHE A 1 43  ? 132.939 116.768 107.180 1.00 94.38  ? 43  PHE A CA  1 
ATOM 358  C C   . PHE A 1 43  ? 133.432 116.146 108.478 1.00 97.84  ? 43  PHE A C   1 
ATOM 359  O O   . PHE A 1 43  ? 134.169 115.162 108.480 1.00 103.96 ? 43  PHE A O   1 
ATOM 360  C CB  . PHE A 1 43  ? 131.639 116.093 106.737 1.00 93.67  ? 43  PHE A CB  1 
ATOM 361  C CG  . PHE A 1 43  ? 131.720 114.604 106.668 1.00 96.37  ? 43  PHE A CG  1 
ATOM 362  C CD1 . PHE A 1 43  ? 132.197 113.979 105.533 1.00 102.76 ? 43  PHE A CD1 1 
ATOM 363  C CD2 . PHE A 1 43  ? 131.303 113.825 107.732 1.00 95.23  ? 43  PHE A CD2 1 
ATOM 364  C CE1 . PHE A 1 43  ? 132.268 112.603 105.460 1.00 104.77 ? 43  PHE A CE1 1 
ATOM 365  C CE2 . PHE A 1 43  ? 131.370 112.449 107.666 1.00 101.89 ? 43  PHE A CE2 1 
ATOM 366  C CZ  . PHE A 1 43  ? 131.854 111.837 106.528 1.00 108.32 ? 43  PHE A CZ  1 
ATOM 367  N N   . CYS A 1 44  ? 133.012 116.738 109.589 1.00 96.35  ? 44  CYS A N   1 
ATOM 368  C CA  . CYS A 1 44  ? 133.384 116.276 110.918 1.00 93.24  ? 44  CYS A CA  1 
ATOM 369  C C   . CYS A 1 44  ? 132.462 115.142 111.341 1.00 94.46  ? 44  CYS A C   1 
ATOM 370  O O   . CYS A 1 44  ? 131.244 115.230 111.156 1.00 102.70 ? 44  CYS A O   1 
ATOM 371  C CB  . CYS A 1 44  ? 133.299 117.420 111.925 1.00 92.65  ? 44  CYS A CB  1 
ATOM 372  S SG  . CYS A 1 44  ? 134.322 118.838 111.525 1.00 108.08 ? 44  CYS A SG  1 
ATOM 373  N N   . LEU A 1 45  ? 133.036 114.084 111.906 1.00 91.92  ? 45  LEU A N   1 
ATOM 374  C CA  . LEU A 1 45  ? 132.219 112.975 112.378 1.00 97.06  ? 45  LEU A CA  1 
ATOM 375  C C   . LEU A 1 45  ? 133.039 112.116 113.326 1.00 101.32 ? 45  LEU A C   1 
ATOM 376  O O   . LEU A 1 45  ? 134.255 111.983 113.167 1.00 106.06 ? 45  LEU A O   1 
ATOM 377  C CB  . LEU A 1 45  ? 131.690 112.131 111.213 1.00 100.74 ? 45  LEU A CB  1 
ATOM 378  C CG  . LEU A 1 45  ? 130.767 110.965 111.571 1.00 99.55  ? 45  LEU A CG  1 
ATOM 379  C CD1 . LEU A 1 45  ? 129.558 111.459 112.349 1.00 94.44  ? 45  LEU A CD1 1 
ATOM 380  C CD2 . LEU A 1 45  ? 130.335 110.216 110.321 1.00 97.90  ? 45  LEU A CD2 1 
ATOM 381  N N   . GLY A 1 46  ? 132.361 111.533 114.311 1.00 98.77  ? 46  GLY A N   1 
ATOM 382  C CA  . GLY A 1 46  ? 133.003 110.664 115.265 1.00 99.49  ? 46  GLY A CA  1 
ATOM 383  C C   . GLY A 1 46  ? 132.604 110.976 116.691 1.00 92.61  ? 46  GLY A C   1 
ATOM 384  O O   . GLY A 1 46  ? 132.624 112.131 117.126 1.00 89.74  ? 46  GLY A O   1 
ATOM 385  N N   . PRO A 1 47  ? 132.229 109.945 117.446 1.00 89.65  ? 47  PRO A N   1 
ATOM 386  C CA  . PRO A 1 47  ? 131.801 110.159 118.831 1.00 87.37  ? 47  PRO A CA  1 
ATOM 387  C C   . PRO A 1 47  ? 132.916 110.772 119.665 1.00 88.39  ? 47  PRO A C   1 
ATOM 388  O O   . PRO A 1 47  ? 134.101 110.540 119.421 1.00 89.97  ? 47  PRO A O   1 
ATOM 389  C CB  . PRO A 1 47  ? 131.447 108.749 119.315 1.00 85.21  ? 47  PRO A CB  1 
ATOM 390  C CG  . PRO A 1 47  ? 131.148 107.989 118.070 1.00 86.48  ? 47  PRO A CG  1 
ATOM 391  C CD  . PRO A 1 47  ? 132.073 108.542 117.031 1.00 90.23  ? 47  PRO A CD  1 
ATOM 392  N N   . CYS A 1 48  ? 132.520 111.571 120.655 1.00 83.77  ? 48  CYS A N   1 
ATOM 393  C CA  . CYS A 1 48  ? 133.462 112.279 121.515 1.00 74.64  ? 48  CYS A CA  1 
ATOM 394  C C   . CYS A 1 48  ? 133.465 111.660 122.905 1.00 76.22  ? 48  CYS A C   1 
ATOM 395  O O   . CYS A 1 48  ? 132.525 111.880 123.684 1.00 67.74  ? 48  CYS A O   1 
ATOM 396  C CB  . CYS A 1 48  ? 133.097 113.763 121.594 1.00 67.50  ? 48  CYS A CB  1 
ATOM 397  S SG  . CYS A 1 48  ? 133.194 114.639 120.028 1.00 96.53  ? 48  CYS A SG  1 
ATOM 398  N N   . PRO A 1 49  ? 134.483 110.887 123.267 1.00 81.65  ? 49  PRO A N   1 
ATOM 399  C CA  . PRO A 1 49  ? 134.563 110.365 124.634 1.00 81.63  ? 49  PRO A CA  1 
ATOM 400  C C   . PRO A 1 49  ? 135.192 111.382 125.568 1.00 81.85  ? 49  PRO A C   1 
ATOM 401  O O   . PRO A 1 49  ? 135.499 112.499 125.143 1.00 83.62  ? 49  PRO A O   1 
ATOM 402  C CB  . PRO A 1 49  ? 135.434 109.109 124.486 1.00 82.55  ? 49  PRO A CB  1 
ATOM 403  C CG  . PRO A 1 49  ? 135.852 109.056 123.017 1.00 80.42  ? 49  PRO A CG  1 
ATOM 404  C CD  . PRO A 1 49  ? 135.594 110.404 122.439 1.00 81.10  ? 49  PRO A CD  1 
ATOM 405  N N   . TYR A 1 50  ? 135.388 111.019 126.837 1.00 81.45  ? 50  TYR A N   1 
ATOM 406  C CA  . TYR A 1 50  ? 135.954 111.971 127.786 1.00 81.32  ? 50  TYR A CA  1 
ATOM 407  C C   . TYR A 1 50  ? 137.395 112.314 127.430 1.00 87.65  ? 50  TYR A C   1 
ATOM 408  O O   . TYR A 1 50  ? 137.778 113.489 127.413 1.00 89.31  ? 50  TYR A O   1 
ATOM 409  C CB  . TYR A 1 50  ? 135.872 111.422 129.209 1.00 77.04  ? 50  TYR A CB  1 
ATOM 410  C CG  . TYR A 1 50  ? 136.208 112.454 130.263 1.00 78.51  ? 50  TYR A CG  1 
ATOM 411  C CD1 . TYR A 1 50  ? 136.132 113.811 129.982 1.00 74.12  ? 50  TYR A CD1 1 
ATOM 412  C CD2 . TYR A 1 50  ? 136.613 112.074 131.533 1.00 87.11  ? 50  TYR A CD2 1 
ATOM 413  C CE1 . TYR A 1 50  ? 136.441 114.755 130.930 1.00 72.11  ? 50  TYR A CE1 1 
ATOM 414  C CE2 . TYR A 1 50  ? 136.925 113.018 132.491 1.00 87.88  ? 50  TYR A CE2 1 
ATOM 415  C CZ  . TYR A 1 50  ? 136.835 114.356 132.182 1.00 82.41  ? 50  TYR A CZ  1 
ATOM 416  O OH  . TYR A 1 50  ? 137.143 115.301 133.130 1.00 81.69  ? 50  TYR A OH  1 
ATOM 417  N N   . ILE A 1 51  ? 138.208 111.304 127.134 1.00 88.97  ? 51  ILE A N   1 
ATOM 418  C CA  . ILE A 1 51  ? 139.613 111.550 126.839 1.00 90.75  ? 51  ILE A CA  1 
ATOM 419  C C   . ILE A 1 51  ? 139.741 111.896 125.364 1.00 91.06  ? 51  ILE A C   1 
ATOM 420  O O   . ILE A 1 51  ? 140.104 111.047 124.543 1.00 93.97  ? 51  ILE A O   1 
ATOM 421  C CB  . ILE A 1 51  ? 140.488 110.338 127.204 1.00 92.08  ? 51  ILE A CB  1 
ATOM 422  C CG1 . ILE A 1 51  ? 140.154 109.844 128.613 1.00 95.78  ? 51  ILE A CG1 1 
ATOM 423  C CG2 . ILE A 1 51  ? 141.963 110.699 127.110 1.00 86.43  ? 51  ILE A CG2 1 
ATOM 424  C CD1 . ILE A 1 51  ? 140.424 110.860 129.702 1.00 92.66  ? 51  ILE A CD1 1 
ATOM 425  N N   . TRP A 1 52  ? 139.446 113.149 125.022 1.00 88.53  ? 52  TRP A N   1 
ATOM 426  C CA  . TRP A 1 52  ? 139.553 113.610 123.645 1.00 86.91  ? 52  TRP A CA  1 
ATOM 427  C C   . TRP A 1 52  ? 139.630 115.130 123.604 1.00 80.02  ? 52  TRP A C   1 
ATOM 428  O O   . TRP A 1 52  ? 139.820 115.775 124.639 1.00 78.31  ? 52  TRP A O   1 
ATOM 429  C CB  . TRP A 1 52  ? 138.380 113.099 122.804 1.00 85.91  ? 52  TRP A CB  1 
ATOM 430  C CG  . TRP A 1 52  ? 138.707 113.015 121.342 1.00 87.20  ? 52  TRP A CG  1 
ATOM 431  C CD1 . TRP A 1 52  ? 138.134 113.725 120.331 1.00 87.43  ? 52  TRP A CD1 1 
ATOM 432  C CD2 . TRP A 1 52  ? 139.709 112.192 120.736 1.00 92.47  ? 52  TRP A CD2 1 
ATOM 433  N NE1 . TRP A 1 52  ? 138.707 113.386 119.131 1.00 88.57  ? 52  TRP A NE1 1 
ATOM 434  C CE2 . TRP A 1 52  ? 139.679 112.447 119.354 1.00 93.34  ? 52  TRP A CE2 1 
ATOM 435  C CE3 . TRP A 1 52  ? 140.626 111.259 121.229 1.00 96.69  ? 52  TRP A CE3 1 
ATOM 436  C CZ2 . TRP A 1 52  ? 140.526 111.805 118.460 1.00 98.15  ? 52  TRP A CZ2 1 
ATOM 437  C CZ3 . TRP A 1 52  ? 141.466 110.624 120.340 1.00 102.10 ? 52  TRP A CZ3 1 
ATOM 438  C CH2 . TRP A 1 52  ? 141.411 110.898 118.971 1.00 100.69 ? 52  TRP A CH2 1 
ATOM 439  N N   . SER A 1 53  ? 139.503 115.711 122.412 1.00 78.04  ? 53  SER A N   1 
ATOM 440  C CA  . SER A 1 53  ? 139.653 117.153 122.229 1.00 79.29  ? 53  SER A CA  1 
ATOM 441  C C   . SER A 1 53  ? 138.318 117.834 122.511 1.00 79.32  ? 53  SER A C   1 
ATOM 442  O O   . SER A 1 53  ? 137.535 118.150 121.614 1.00 85.26  ? 53  SER A O   1 
ATOM 443  C CB  . SER A 1 53  ? 140.159 117.464 120.827 1.00 83.03  ? 53  SER A CB  1 
ATOM 444  O OG  . SER A 1 53  ? 140.318 118.860 120.643 1.00 85.81  ? 53  SER A OG  1 
ATOM 445  N N   . LEU A 1 54  ? 138.063 118.062 123.796 1.00 69.91  ? 54  LEU A N   1 
ATOM 446  C CA  . LEU A 1 54  ? 136.908 118.827 124.237 1.00 62.94  ? 54  LEU A CA  1 
ATOM 447  C C   . LEU A 1 54  ? 137.341 120.258 124.521 1.00 66.21  ? 54  LEU A C   1 
ATOM 448  O O   . LEU A 1 54  ? 138.359 120.490 125.178 1.00 72.36  ? 54  LEU A O   1 
ATOM 449  C CB  . LEU A 1 54  ? 136.291 118.193 125.482 1.00 57.32  ? 54  LEU A CB  1 
ATOM 450  C CG  . LEU A 1 54  ? 135.978 116.699 125.368 1.00 55.52  ? 54  LEU A CG  1 
ATOM 451  C CD1 . LEU A 1 54  ? 135.686 116.100 126.726 1.00 57.36  ? 54  LEU A CD1 1 
ATOM 452  C CD2 . LEU A 1 54  ? 134.813 116.462 124.442 1.00 58.20  ? 54  LEU A CD2 1 
ATOM 453  N N   . ASP A 1 55  ? 136.566 121.218 124.017 1.00 63.86  ? 55  ASP A N   1 
ATOM 454  C CA  . ASP A 1 55  ? 136.998 122.613 124.000 1.00 68.41  ? 55  ASP A CA  1 
ATOM 455  C C   . ASP A 1 55  ? 136.540 123.392 125.233 1.00 66.35  ? 55  ASP A C   1 
ATOM 456  O O   . ASP A 1 55  ? 137.365 123.955 125.959 1.00 65.91  ? 55  ASP A O   1 
ATOM 457  C CB  . ASP A 1 55  ? 136.494 123.288 122.723 1.00 67.09  ? 55  ASP A CB  1 
ATOM 458  C CG  . ASP A 1 55  ? 135.035 123.015 122.470 1.00 71.00  ? 55  ASP A CG  1 
ATOM 459  O OD1 . ASP A 1 55  ? 134.429 122.294 123.289 1.00 66.74  ? 55  ASP A OD1 1 
ATOM 460  O OD2 . ASP A 1 55  ? 134.495 123.518 121.464 1.00 78.28  ? 55  ASP A OD2 1 
ATOM 461  N N   . THR A 1 56  ? 135.234 123.446 125.474 1.00 62.61  ? 56  THR A N   1 
ATOM 462  C CA  . THR A 1 56  ? 134.678 124.210 126.580 1.00 58.72  ? 56  THR A CA  1 
ATOM 463  C C   . THR A 1 56  ? 134.450 123.312 127.791 1.00 53.54  ? 56  THR A C   1 
ATOM 464  O O   . THR A 1 56  ? 134.682 122.103 127.756 1.00 57.03  ? 56  THR A O   1 
ATOM 465  C CB  . THR A 1 56  ? 133.369 124.890 126.165 1.00 56.61  ? 56  THR A CB  1 
ATOM 466  O OG1 . THR A 1 56  ? 132.458 123.911 125.655 1.00 53.32  ? 56  THR A OG1 1 
ATOM 467  C CG2 . THR A 1 56  ? 133.631 125.927 125.095 1.00 62.15  ? 56  THR A CG2 1 
ATOM 468  N N   . GLN A 1 57  ? 134.001 123.931 128.884 1.00 46.01  ? 57  GLN A N   1 
ATOM 469  C CA  . GLN A 1 57  ? 133.743 123.168 130.098 1.00 43.95  ? 57  GLN A CA  1 
ATOM 470  C C   . GLN A 1 57  ? 132.436 122.400 130.011 1.00 40.15  ? 57  GLN A C   1 
ATOM 471  O O   . GLN A 1 57  ? 132.320 121.306 130.576 1.00 39.83  ? 57  GLN A O   1 
ATOM 472  C CB  . GLN A 1 57  ? 133.730 124.092 131.309 1.00 42.26  ? 57  GLN A CB  1 
ATOM 473  C CG  . GLN A 1 57  ? 133.669 123.359 132.624 1.00 34.22  ? 57  GLN A CG  1 
ATOM 474  C CD  . GLN A 1 57  ? 134.142 124.212 133.767 1.00 36.32  ? 57  GLN A CD  1 
ATOM 475  O OE1 . GLN A 1 57  ? 134.179 125.433 133.669 1.00 39.40  ? 57  GLN A OE1 1 
ATOM 476  N NE2 . GLN A 1 57  ? 134.517 123.572 134.861 1.00 45.41  ? 57  GLN A NE2 1 
ATOM 477  N N   . TYR A 1 58  ? 131.443 122.955 129.320 1.00 41.17  ? 58  TYR A N   1 
ATOM 478  C CA  . TYR A 1 58  ? 130.181 122.244 129.167 1.00 43.75  ? 58  TYR A CA  1 
ATOM 479  C C   . TYR A 1 58  ? 130.380 120.940 128.413 1.00 46.72  ? 58  TYR A C   1 
ATOM 480  O O   . TYR A 1 58  ? 129.703 119.944 128.691 1.00 48.67  ? 58  TYR A O   1 
ATOM 481  C CB  . TYR A 1 58  ? 129.162 123.121 128.452 1.00 38.44  ? 58  TYR A CB  1 
ATOM 482  C CG  . TYR A 1 58  ? 127.925 122.365 128.063 1.00 31.69  ? 58  TYR A CG  1 
ATOM 483  C CD1 . TYR A 1 58  ? 127.009 121.969 129.019 1.00 30.16  ? 58  TYR A CD1 1 
ATOM 484  C CD2 . TYR A 1 58  ? 127.680 122.032 126.747 1.00 33.20  ? 58  TYR A CD2 1 
ATOM 485  C CE1 . TYR A 1 58  ? 125.885 121.272 128.673 1.00 29.60  ? 58  TYR A CE1 1 
ATOM 486  C CE2 . TYR A 1 58  ? 126.557 121.330 126.394 1.00 36.83  ? 58  TYR A CE2 1 
ATOM 487  C CZ  . TYR A 1 58  ? 125.663 120.955 127.360 1.00 30.75  ? 58  TYR A CZ  1 
ATOM 488  O OH  . TYR A 1 58  ? 124.538 120.256 127.010 1.00 37.99  ? 58  TYR A OH  1 
ATOM 489  N N   . SER A 1 59  ? 131.299 120.927 127.448 1.00 47.00  ? 59  SER A N   1 
ATOM 490  C CA  . SER A 1 59  ? 131.589 119.691 126.737 1.00 41.88  ? 59  SER A CA  1 
ATOM 491  C C   . SER A 1 59  ? 132.141 118.636 127.683 1.00 46.50  ? 59  SER A C   1 
ATOM 492  O O   . SER A 1 59  ? 131.743 117.470 127.617 1.00 47.18  ? 59  SER A O   1 
ATOM 493  C CB  . SER A 1 59  ? 132.562 119.960 125.593 1.00 46.50  ? 59  SER A CB  1 
ATOM 494  O OG  . SER A 1 59  ? 133.637 120.771 126.024 1.00 53.62  ? 59  SER A OG  1 
ATOM 495  N N   . LYS A 1 60  ? 133.046 119.028 128.582 1.00 48.61  ? 60  LYS A N   1 
ATOM 496  C CA  . LYS A 1 60  ? 133.587 118.070 129.542 1.00 46.80  ? 60  LYS A CA  1 
ATOM 497  C C   . LYS A 1 60  ? 132.507 117.576 130.492 1.00 48.54  ? 60  LYS A C   1 
ATOM 498  O O   . LYS A 1 60  ? 132.471 116.390 130.839 1.00 51.86  ? 60  LYS A O   1 
ATOM 499  C CB  . LYS A 1 60  ? 134.742 118.693 130.321 1.00 43.99  ? 60  LYS A CB  1 
ATOM 500  C CG  . LYS A 1 60  ? 135.891 119.155 129.448 1.00 48.71  ? 60  LYS A CG  1 
ATOM 501  C CD  . LYS A 1 60  ? 137.156 119.374 130.256 1.00 58.48  ? 60  LYS A CD  1 
ATOM 502  C CE  . LYS A 1 60  ? 137.679 118.066 130.823 1.00 67.68  ? 60  LYS A CE  1 
ATOM 503  N NZ  . LYS A 1 60  ? 138.984 118.233 131.519 1.00 63.20  ? 60  LYS A NZ  1 
ATOM 504  N N   . VAL A 1 61  ? 131.616 118.469 130.924 1.00 47.28  ? 61  VAL A N   1 
ATOM 505  C CA  . VAL A 1 61  ? 130.530 118.060 131.810 1.00 42.92  ? 61  VAL A CA  1 
ATOM 506  C C   . VAL A 1 61  ? 129.614 117.062 131.113 1.00 48.32  ? 61  VAL A C   1 
ATOM 507  O O   . VAL A 1 61  ? 129.238 116.032 131.687 1.00 53.93  ? 61  VAL A O   1 
ATOM 508  C CB  . VAL A 1 61  ? 129.754 119.293 132.299 1.00 35.17  ? 61  VAL A CB  1 
ATOM 509  C CG1 . VAL A 1 61  ? 128.558 118.867 133.115 1.00 40.61  ? 61  VAL A CG1 1 
ATOM 510  C CG2 . VAL A 1 61  ? 130.660 120.183 133.113 1.00 38.73  ? 61  VAL A CG2 1 
ATOM 511  N N   . LEU A 1 62  ? 129.244 117.346 129.866 1.00 46.30  ? 62  LEU A N   1 
ATOM 512  C CA  . LEU A 1 62  ? 128.387 116.430 129.124 1.00 44.41  ? 62  LEU A CA  1 
ATOM 513  C C   . LEU A 1 62  ? 129.084 115.098 128.892 1.00 51.21  ? 62  LEU A C   1 
ATOM 514  O O   . LEU A 1 62  ? 128.454 114.037 128.960 1.00 59.71  ? 62  LEU A O   1 
ATOM 515  C CB  . LEU A 1 62  ? 127.975 117.067 127.800 1.00 41.61  ? 62  LEU A CB  1 
ATOM 516  C CG  . LEU A 1 62  ? 126.483 117.024 127.490 1.00 39.74  ? 62  LEU A CG  1 
ATOM 517  C CD1 . LEU A 1 62  ? 126.015 115.597 127.427 1.00 50.56  ? 62  LEU A CD1 1 
ATOM 518  C CD2 . LEU A 1 62  ? 125.710 117.762 128.548 1.00 37.70  ? 62  LEU A CD2 1 
ATOM 519  N N   . ALA A 1 63  ? 130.387 115.133 128.607 1.00 49.76  ? 63  ALA A N   1 
ATOM 520  C CA  . ALA A 1 63  ? 131.135 113.900 128.409 1.00 52.78  ? 63  ALA A CA  1 
ATOM 521  C C   . ALA A 1 63  ? 131.165 113.067 129.680 1.00 62.25  ? 63  ALA A C   1 
ATOM 522  O O   . ALA A 1 63  ? 131.022 111.842 129.628 1.00 68.27  ? 63  ALA A O   1 
ATOM 523  C CB  . ALA A 1 63  ? 132.552 114.218 127.942 1.00 55.18  ? 63  ALA A CB  1 
ATOM 524  N N   . LEU A 1 64  ? 131.356 113.712 130.832 1.00 62.77  ? 64  LEU A N   1 
ATOM 525  C CA  . LEU A 1 64  ? 131.312 112.987 132.097 1.00 64.56  ? 64  LEU A CA  1 
ATOM 526  C C   . LEU A 1 64  ? 129.934 112.386 132.337 1.00 67.55  ? 64  LEU A C   1 
ATOM 527  O O   . LEU A 1 64  ? 129.815 111.247 132.808 1.00 74.34  ? 64  LEU A O   1 
ATOM 528  C CB  . LEU A 1 64  ? 131.703 113.912 133.247 1.00 64.72  ? 64  LEU A CB  1 
ATOM 529  C CG  . LEU A 1 64  ? 133.199 114.044 133.506 1.00 69.19  ? 64  LEU A CG  1 
ATOM 530  C CD1 . LEU A 1 64  ? 133.471 115.126 134.527 1.00 70.80  ? 64  LEU A CD1 1 
ATOM 531  C CD2 . LEU A 1 64  ? 133.743 112.717 133.984 1.00 74.40  ? 64  LEU A CD2 1 
ATOM 532  N N   . TYR A 1 65  ? 128.879 113.141 132.020 1.00 63.33  ? 65  TYR A N   1 
ATOM 533  C CA  . TYR A 1 65  ? 127.529 112.607 132.157 1.00 67.84  ? 65  TYR A CA  1 
ATOM 534  C C   . TYR A 1 65  ? 127.346 111.366 131.299 1.00 73.67  ? 65  TYR A C   1 
ATOM 535  O O   . TYR A 1 65  ? 126.821 110.349 131.766 1.00 78.67  ? 65  TYR A O   1 
ATOM 536  C CB  . TYR A 1 65  ? 126.500 113.667 131.773 1.00 62.47  ? 65  TYR A CB  1 
ATOM 537  C CG  . TYR A 1 65  ? 125.067 113.198 131.872 1.00 61.78  ? 65  TYR A CG  1 
ATOM 538  C CD1 . TYR A 1 65  ? 124.680 112.279 132.831 1.00 66.47  ? 65  TYR A CD1 1 
ATOM 539  C CD2 . TYR A 1 65  ? 124.103 113.674 131.002 1.00 61.03  ? 65  TYR A CD2 1 
ATOM 540  C CE1 . TYR A 1 65  ? 123.378 111.850 132.922 1.00 69.07  ? 65  TYR A CE1 1 
ATOM 541  C CE2 . TYR A 1 65  ? 122.797 113.251 131.088 1.00 65.64  ? 65  TYR A CE2 1 
ATOM 542  C CZ  . TYR A 1 65  ? 122.440 112.340 132.051 1.00 70.52  ? 65  TYR A CZ  1 
ATOM 543  O OH  . TYR A 1 65  ? 121.137 111.911 132.144 1.00 76.02  ? 65  TYR A OH  1 
ATOM 544  N N   . ASN A 1 66  ? 127.778 111.430 130.042 1.00 72.22  ? 66  ASN A N   1 
ATOM 545  C CA  . ASN A 1 66  ? 127.626 110.283 129.158 1.00 76.22  ? 66  ASN A CA  1 
ATOM 546  C C   . ASN A 1 66  ? 128.472 109.111 129.634 1.00 80.39  ? 66  ASN A C   1 
ATOM 547  O O   . ASN A 1 66  ? 128.067 107.950 129.502 1.00 88.08  ? 66  ASN A O   1 
ATOM 548  C CB  . ASN A 1 66  ? 127.988 110.669 127.727 1.00 72.53  ? 66  ASN A CB  1 
ATOM 549  C CG  . ASN A 1 66  ? 127.411 109.715 126.706 1.00 79.84  ? 66  ASN A CG  1 
ATOM 550  O OD1 . ASN A 1 66  ? 126.330 109.162 126.902 1.00 81.23  ? 66  ASN A OD1 1 
ATOM 551  N ND2 . ASN A 1 66  ? 128.133 109.508 125.611 1.00 86.46  ? 66  ASN A ND2 1 
ATOM 552  N N   . GLN A 1 67  ? 129.649 109.395 130.194 1.00 73.64  ? 67  GLN A N   1 
ATOM 553  C CA  . GLN A 1 67  ? 130.505 108.334 130.710 1.00 75.84  ? 67  GLN A CA  1 
ATOM 554  C C   . GLN A 1 67  ? 129.852 107.619 131.885 1.00 80.11  ? 67  GLN A C   1 
ATOM 555  O O   . GLN A 1 67  ? 129.937 106.391 131.998 1.00 84.01  ? 67  GLN A O   1 
ATOM 556  C CB  . GLN A 1 67  ? 131.860 108.912 131.111 1.00 75.59  ? 67  GLN A CB  1 
ATOM 557  C CG  . GLN A 1 67  ? 132.826 107.905 131.697 1.00 80.09  ? 67  GLN A CG  1 
ATOM 558  C CD  . GLN A 1 67  ? 134.184 108.511 131.985 1.00 87.68  ? 67  GLN A CD  1 
ATOM 559  O OE1 . GLN A 1 67  ? 134.449 109.660 131.632 1.00 85.90  ? 67  GLN A OE1 1 
ATOM 560  N NE2 . GLN A 1 67  ? 135.052 107.742 132.629 1.00 95.03  ? 67  GLN A NE2 1 
ATOM 561  N N   . HIS A 1 68  ? 129.199 108.368 132.773 1.00 80.59  ? 68  HIS A N   1 
ATOM 562  C CA  . HIS A 1 68  ? 128.510 107.748 133.898 1.00 85.65  ? 68  HIS A CA  1 
ATOM 563  C C   . HIS A 1 68  ? 127.084 107.330 133.566 1.00 85.57  ? 68  HIS A C   1 
ATOM 564  O O   . HIS A 1 68  ? 126.430 106.706 134.407 1.00 90.75  ? 68  HIS A O   1 
ATOM 565  C CB  . HIS A 1 68  ? 128.486 108.692 135.102 1.00 87.00  ? 68  HIS A CB  1 
ATOM 566  C CG  . HIS A 1 68  ? 129.844 109.076 135.600 1.00 85.54  ? 68  HIS A CG  1 
ATOM 567  N ND1 . HIS A 1 68  ? 130.530 110.170 135.120 1.00 81.25  ? 68  HIS A ND1 1 
ATOM 568  C CD2 . HIS A 1 68  ? 130.635 108.522 136.548 1.00 86.17  ? 68  HIS A CD2 1 
ATOM 569  C CE1 . HIS A 1 68  ? 131.690 110.268 135.744 1.00 82.27  ? 68  HIS A CE1 1 
ATOM 570  N NE2 . HIS A 1 68  ? 131.778 109.280 136.616 1.00 87.94  ? 68  HIS A NE2 1 
ATOM 571  N N   . ASN A 1 69  ? 126.586 107.661 132.380 1.00 84.82  ? 69  ASN A N   1 
ATOM 572  C CA  . ASN A 1 69  ? 125.230 107.304 131.966 1.00 87.62  ? 69  ASN A CA  1 
ATOM 573  C C   . ASN A 1 69  ? 125.263 106.948 130.488 1.00 93.45  ? 69  ASN A C   1 
ATOM 574  O O   . ASN A 1 69  ? 125.072 107.805 129.618 1.00 92.91  ? 69  ASN A O   1 
ATOM 575  C CB  . ASN A 1 69  ? 124.252 108.447 132.247 1.00 83.98  ? 69  ASN A CB  1 
ATOM 576  C CG  . ASN A 1 69  ? 122.807 107.998 132.235 1.00 90.74  ? 69  ASN A CG  1 
ATOM 577  O OD1 . ASN A 1 69  ? 122.442 107.054 131.535 1.00 95.45  ? 69  ASN A OD1 1 
ATOM 578  N ND2 . ASN A 1 69  ? 121.973 108.675 133.014 1.00 84.49  ? 69  ASN A ND2 1 
ATOM 579  N N   . PRO A 1 70  ? 125.521 105.678 130.164 1.00 96.36  ? 70  PRO A N   1 
ATOM 580  C CA  . PRO A 1 70  ? 125.665 105.280 128.756 1.00 95.86  ? 70  PRO A CA  1 
ATOM 581  C C   . PRO A 1 70  ? 124.436 105.569 127.909 1.00 95.55  ? 70  PRO A C   1 
ATOM 582  O O   . PRO A 1 70  ? 124.522 106.283 126.905 1.00 95.57  ? 70  PRO A O   1 
ATOM 583  C CB  . PRO A 1 70  ? 125.931 103.772 128.848 1.00 99.01  ? 70  PRO A CB  1 
ATOM 584  C CG  . PRO A 1 70  ? 126.476 103.564 130.223 1.00 97.11  ? 70  PRO A CG  1 
ATOM 585  C CD  . PRO A 1 70  ? 125.757 104.554 131.085 1.00 98.38  ? 70  PRO A CD  1 
ATOM 586  N N   . GLY A 1 71  ? 123.289 105.023 128.301 1.00 94.22  ? 71  GLY A N   1 
ATOM 587  C CA  . GLY A 1 71  ? 122.070 105.228 127.545 1.00 100.32 ? 71  GLY A CA  1 
ATOM 588  C C   . GLY A 1 71  ? 121.428 106.570 127.830 1.00 103.60 ? 71  GLY A C   1 
ATOM 589  O O   . GLY A 1 71  ? 120.378 106.639 128.476 1.00 106.05 ? 71  GLY A O   1 
ATOM 590  N N   . ALA A 1 72  ? 122.048 107.646 127.351 1.00 99.09  ? 72  ALA A N   1 
ATOM 591  C CA  . ALA A 1 72  ? 121.598 108.996 127.650 1.00 91.92  ? 72  ALA A CA  1 
ATOM 592  C C   . ALA A 1 72  ? 121.308 109.841 126.421 1.00 88.20  ? 72  ALA A C   1 
ATOM 593  O O   . ALA A 1 72  ? 120.562 110.816 126.531 1.00 85.30  ? 72  ALA A O   1 
ATOM 594  C CB  . ALA A 1 72  ? 122.640 109.725 128.511 1.00 85.26  ? 72  ALA A CB  1 
ATOM 595  N N   . SER A 1 73  ? 121.906 109.520 125.272 1.00 87.79  ? 73  SER A N   1 
ATOM 596  C CA  . SER A 1 73  ? 121.673 110.212 124.006 1.00 87.99  ? 73  SER A CA  1 
ATOM 597  C C   . SER A 1 73  ? 122.210 111.637 124.026 1.00 84.74  ? 73  SER A C   1 
ATOM 598  O O   . SER A 1 73  ? 122.160 112.337 123.010 1.00 88.55  ? 73  SER A O   1 
ATOM 599  C CB  . SER A 1 73  ? 120.184 110.222 123.648 1.00 88.59  ? 73  SER A CB  1 
ATOM 600  O OG  . SER A 1 73  ? 119.435 110.959 124.601 1.00 83.70  ? 73  SER A OG  1 
ATOM 601  N N   . ALA A 1 74  ? 122.727 112.078 125.166 1.00 75.61  ? 74  ALA A N   1 
ATOM 602  C CA  . ALA A 1 74  ? 123.293 113.413 125.294 1.00 65.17  ? 74  ALA A CA  1 
ATOM 603  C C   . ALA A 1 74  ? 124.810 113.289 125.314 1.00 65.54  ? 74  ALA A C   1 
ATOM 604  O O   . ALA A 1 74  ? 125.372 112.608 126.176 1.00 69.47  ? 74  ALA A O   1 
ATOM 605  C CB  . ALA A 1 74  ? 122.774 114.100 126.552 1.00 62.83  ? 74  ALA A CB  1 
ATOM 606  N N   . ALA A 1 75  ? 125.470 113.948 124.370 1.00 61.35  ? 75  ALA A N   1 
ATOM 607  C CA  . ALA A 1 75  ? 126.919 113.907 124.265 1.00 58.76  ? 75  ALA A CA  1 
ATOM 608  C C   . ALA A 1 75  ? 127.356 115.013 123.324 1.00 57.49  ? 75  ALA A C   1 
ATOM 609  O O   . ALA A 1 75  ? 126.602 115.395 122.423 1.00 62.43  ? 75  ALA A O   1 
ATOM 610  C CB  . ALA A 1 75  ? 127.402 112.543 123.753 1.00 66.95  ? 75  ALA A CB  1 
ATOM 611  N N   . PRO A 1 76  ? 128.560 115.549 123.504 1.00 56.15  ? 76  PRO A N   1 
ATOM 612  C CA  . PRO A 1 76  ? 129.049 116.564 122.570 1.00 61.13  ? 76  PRO A CA  1 
ATOM 613  C C   . PRO A 1 76  ? 129.182 115.986 121.172 1.00 71.37  ? 76  PRO A C   1 
ATOM 614  O O   . PRO A 1 76  ? 129.455 114.799 120.987 1.00 77.09  ? 76  PRO A O   1 
ATOM 615  C CB  . PRO A 1 76  ? 130.411 116.956 123.151 1.00 58.97  ? 76  PRO A CB  1 
ATOM 616  C CG  . PRO A 1 76  ? 130.821 115.793 123.962 1.00 56.80  ? 76  PRO A CG  1 
ATOM 617  C CD  . PRO A 1 76  ? 129.560 115.225 124.532 1.00 57.28  ? 76  PRO A CD  1 
ATOM 618  N N   . CYS A 1 77  ? 128.973 116.842 120.181 1.00 72.00  ? 77  CYS A N   1 
ATOM 619  C CA  . CYS A 1 77  ? 128.987 116.433 118.789 1.00 73.37  ? 77  CYS A CA  1 
ATOM 620  C C   . CYS A 1 77  ? 130.205 117.022 118.091 1.00 76.53  ? 77  CYS A C   1 
ATOM 621  O O   . CYS A 1 77  ? 130.722 118.073 118.475 1.00 75.73  ? 77  CYS A O   1 
ATOM 622  C CB  . CYS A 1 77  ? 127.701 116.867 118.084 1.00 75.06  ? 77  CYS A CB  1 
ATOM 623  S SG  . CYS A 1 77  ? 127.374 116.018 116.533 1.00 94.79  ? 77  CYS A SG  1 
ATOM 624  N N   . CYS A 1 78  ? 130.665 116.315 117.063 1.00 78.58  ? 78  CYS A N   1 
ATOM 625  C CA  . CYS A 1 78  ? 131.845 116.714 116.307 1.00 77.98  ? 78  CYS A CA  1 
ATOM 626  C C   . CYS A 1 78  ? 131.455 117.795 115.306 1.00 76.59  ? 78  CYS A C   1 
ATOM 627  O O   . CYS A 1 78  ? 130.636 117.554 114.414 1.00 78.56  ? 78  CYS A O   1 
ATOM 628  C CB  . CYS A 1 78  ? 132.436 115.493 115.607 1.00 83.93  ? 78  CYS A CB  1 
ATOM 629  S SG  . CYS A 1 78  ? 134.096 115.655 114.911 1.00 98.37  ? 78  CYS A SG  1 
ATOM 630  N N   . VAL A 1 79  ? 132.028 118.984 115.457 1.00 71.96  ? 79  VAL A N   1 
ATOM 631  C CA  . VAL A 1 79  ? 131.597 120.143 114.678 1.00 72.40  ? 79  VAL A CA  1 
ATOM 632  C C   . VAL A 1 79  ? 132.818 120.856 114.118 1.00 75.22  ? 79  VAL A C   1 
ATOM 633  O O   . VAL A 1 79  ? 133.931 120.744 114.656 1.00 81.76  ? 79  VAL A O   1 
ATOM 634  C CB  . VAL A 1 79  ? 130.740 121.110 115.524 1.00 76.58  ? 79  VAL A CB  1 
ATOM 635  C CG1 . VAL A 1 79  ? 129.470 120.427 115.955 1.00 83.20  ? 79  VAL A CG1 1 
ATOM 636  C CG2 . VAL A 1 79  ? 131.524 121.599 116.720 1.00 77.62  ? 79  VAL A CG2 1 
ATOM 637  N N   . PRO A 1 80  ? 132.643 121.598 113.025 1.00 75.14  ? 80  PRO A N   1 
ATOM 638  C CA  . PRO A 1 80  ? 133.770 122.336 112.445 1.00 82.22  ? 80  PRO A CA  1 
ATOM 639  C C   . PRO A 1 80  ? 134.329 123.362 113.414 1.00 86.25  ? 80  PRO A C   1 
ATOM 640  O O   . PRO A 1 80  ? 133.593 123.992 114.174 1.00 86.22  ? 80  PRO A O   1 
ATOM 641  C CB  . PRO A 1 80  ? 133.154 123.012 111.217 1.00 85.11  ? 80  PRO A CB  1 
ATOM 642  C CG  . PRO A 1 80  ? 131.962 122.203 110.897 1.00 84.09  ? 80  PRO A CG  1 
ATOM 643  C CD  . PRO A 1 80  ? 131.433 121.708 112.197 1.00 80.23  ? 80  PRO A CD  1 
ATOM 644  N N   . GLN A 1 81  ? 135.649 123.531 113.375 1.00 95.10  ? 81  GLN A N   1 
ATOM 645  C CA  . GLN A 1 81  ? 136.344 124.526 114.179 1.00 101.51 ? 81  GLN A CA  1 
ATOM 646  C C   . GLN A 1 81  ? 137.187 125.461 113.330 1.00 109.37 ? 81  GLN A C   1 
ATOM 647  O O   . GLN A 1 81  ? 137.209 126.672 113.582 1.00 110.71 ? 81  GLN A O   1 
ATOM 648  C CB  . GLN A 1 81  ? 137.223 123.826 115.224 1.00 95.99  ? 81  GLN A CB  1 
ATOM 649  C CG  . GLN A 1 81  ? 138.089 124.764 116.034 1.00 102.78 ? 81  GLN A CG  1 
ATOM 650  C CD  . GLN A 1 81  ? 139.036 124.021 116.948 1.00 110.37 ? 81  GLN A CD  1 
ATOM 651  O OE1 . GLN A 1 81  ? 139.026 122.791 117.000 1.00 107.61 ? 81  GLN A OE1 1 
ATOM 652  N NE2 . GLN A 1 81  ? 139.864 124.763 117.674 1.00 119.61 ? 81  GLN A NE2 1 
ATOM 653  N N   . ALA A 1 82  ? 137.881 124.933 112.326 1.00 110.43 ? 82  ALA A N   1 
ATOM 654  C CA  . ALA A 1 82  ? 138.681 125.728 111.406 1.00 115.00 ? 82  ALA A CA  1 
ATOM 655  C C   . ALA A 1 82  ? 138.094 125.614 110.007 1.00 115.72 ? 82  ALA A C   1 
ATOM 656  O O   . ALA A 1 82  ? 137.937 124.506 109.485 1.00 113.34 ? 82  ALA A O   1 
ATOM 657  C CB  . ALA A 1 82  ? 140.140 125.269 111.411 1.00 112.64 ? 82  ALA A CB  1 
ATOM 658  N N   . LEU A 1 83  ? 137.780 126.755 109.402 1.00 119.08 ? 83  LEU A N   1 
ATOM 659  C CA  . LEU A 1 83  ? 137.157 126.797 108.088 1.00 121.00 ? 83  LEU A CA  1 
ATOM 660  C C   . LEU A 1 83  ? 137.995 127.650 107.151 1.00 127.29 ? 83  LEU A C   1 
ATOM 661  O O   . LEU A 1 83  ? 138.509 128.700 107.547 1.00 130.86 ? 83  LEU A O   1 
ATOM 662  C CB  . LEU A 1 83  ? 135.732 127.352 108.172 1.00 117.31 ? 83  LEU A CB  1 
ATOM 663  C CG  . LEU A 1 83  ? 134.790 126.588 109.102 1.00 113.03 ? 83  LEU A CG  1 
ATOM 664  C CD1 . LEU A 1 83  ? 133.409 127.215 109.123 1.00 111.49 ? 83  LEU A CD1 1 
ATOM 665  C CD2 . LEU A 1 83  ? 134.708 125.135 108.682 1.00 109.04 ? 83  LEU A CD2 1 
ATOM 666  N N   . GLU A 1 84  ? 138.132 127.195 105.906 1.00 127.54 ? 84  GLU A N   1 
ATOM 667  C CA  . GLU A 1 84  ? 138.906 127.918 104.913 1.00 131.09 ? 84  GLU A CA  1 
ATOM 668  C C   . GLU A 1 84  ? 138.032 128.258 103.715 1.00 133.42 ? 84  GLU A C   1 
ATOM 669  O O   . GLU A 1 84  ? 137.287 127.402 103.224 1.00 133.91 ? 84  GLU A O   1 
ATOM 670  C CB  . GLU A 1 84  ? 140.120 127.101 104.448 1.00 130.54 ? 84  GLU A CB  1 
ATOM 671  C CG  . GLU A 1 84  ? 141.126 126.806 105.546 1.00 134.54 ? 84  GLU A CG  1 
ATOM 672  C CD  . GLU A 1 84  ? 141.804 128.056 106.076 1.00 136.86 ? 84  GLU A CD  1 
ATOM 673  O OE1 . GLU A 1 84  ? 141.864 129.062 105.339 1.00 140.81 ? 84  GLU A OE1 1 
ATOM 674  O OE2 . GLU A 1 84  ? 142.277 128.031 107.231 1.00 132.01 ? 84  GLU A OE2 1 
ATOM 675  N N   . PRO A 1 85  ? 138.096 129.495 103.230 1.00 138.92 ? 85  PRO A N   1 
ATOM 676  C CA  . PRO A 1 85  ? 137.289 129.874 102.066 1.00 140.99 ? 85  PRO A CA  1 
ATOM 677  C C   . PRO A 1 85  ? 137.713 129.119 100.818 1.00 139.98 ? 85  PRO A C   1 
ATOM 678  O O   . PRO A 1 85  ? 138.881 128.769 100.637 1.00 138.68 ? 85  PRO A O   1 
ATOM 679  C CB  . PRO A 1 85  ? 137.554 131.377 101.925 1.00 140.83 ? 85  PRO A CB  1 
ATOM 680  C CG  . PRO A 1 85  ? 138.864 131.594 102.601 1.00 142.22 ? 85  PRO A CG  1 
ATOM 681  C CD  . PRO A 1 85  ? 138.901 130.618 103.736 1.00 138.58 ? 85  PRO A CD  1 
ATOM 682  N N   . LEU A 1 86  ? 136.737 128.873 99.949  1.00 139.56 ? 86  LEU A N   1 
ATOM 683  C CA  . LEU A 1 86  ? 136.943 128.141 98.712  1.00 142.01 ? 86  LEU A CA  1 
ATOM 684  C C   . LEU A 1 86  ? 137.103 129.106 97.551  1.00 146.72 ? 86  LEU A C   1 
ATOM 685  O O   . LEU A 1 86  ? 136.256 129.992 97.370  1.00 146.66 ? 86  LEU A O   1 
ATOM 686  C CB  . LEU A 1 86  ? 135.769 127.198 98.444  1.00 138.72 ? 86  LEU A CB  1 
ATOM 687  C CG  . LEU A 1 86  ? 135.770 126.475 97.097  1.00 136.59 ? 86  LEU A CG  1 
ATOM 688  C CD1 . LEU A 1 86  ? 136.907 125.475 97.021  1.00 134.33 ? 86  LEU A CD1 1 
ATOM 689  C CD2 . LEU A 1 86  ? 134.438 125.796 96.863  1.00 132.24 ? 86  LEU A CD2 1 
ATOM 690  N N   . PRO A 1 87  ? 138.170 128.985 96.761  1.00 147.31 ? 87  PRO A N   1 
ATOM 691  C CA  . PRO A 1 87  ? 138.314 129.829 95.565  1.00 148.03 ? 87  PRO A CA  1 
ATOM 692  C C   . PRO A 1 87  ? 137.405 129.336 94.448  1.00 147.89 ? 87  PRO A C   1 
ATOM 693  O O   . PRO A 1 87  ? 137.422 128.156 94.093  1.00 144.83 ? 87  PRO A O   1 
ATOM 694  C CB  . PRO A 1 87  ? 139.795 129.677 95.201  1.00 147.46 ? 87  PRO A CB  1 
ATOM 695  C CG  . PRO A 1 87  ? 140.165 128.332 95.735  1.00 144.08 ? 87  PRO A CG  1 
ATOM 696  C CD  . PRO A 1 87  ? 139.355 128.139 96.989  1.00 144.50 ? 87  PRO A CD  1 
ATOM 697  N N   . ILE A 1 88  ? 136.605 130.249 93.897  1.00 151.83 ? 88  ILE A N   1 
ATOM 698  C CA  . ILE A 1 88  ? 135.674 129.935 92.825  1.00 152.92 ? 88  ILE A CA  1 
ATOM 699  C C   . ILE A 1 88  ? 135.820 130.967 91.717  1.00 156.02 ? 88  ILE A C   1 
ATOM 700  O O   . ILE A 1 88  ? 136.229 132.108 91.942  1.00 157.87 ? 88  ILE A O   1 
ATOM 701  C CB  . ILE A 1 88  ? 134.212 129.895 93.312  1.00 152.85 ? 88  ILE A CB  1 
ATOM 702  C CG1 . ILE A 1 88  ? 133.829 131.241 93.929  1.00 153.84 ? 88  ILE A CG1 1 
ATOM 703  C CG2 . ILE A 1 88  ? 134.006 128.759 94.299  1.00 149.43 ? 88  ILE A CG2 1 
ATOM 704  C CD1 . ILE A 1 88  ? 132.345 131.418 94.137  1.00 150.86 ? 88  ILE A CD1 1 
ATOM 705  N N   . VAL A 1 89  ? 135.465 130.546 90.505  1.00 157.59 ? 89  VAL A N   1 
ATOM 706  C CA  . VAL A 1 89  ? 135.400 131.424 89.345  1.00 160.32 ? 89  VAL A CA  1 
ATOM 707  C C   . VAL A 1 89  ? 134.002 131.316 88.756  1.00 159.17 ? 89  VAL A C   1 
ATOM 708  O O   . VAL A 1 89  ? 133.577 130.228 88.353  1.00 154.99 ? 89  VAL A O   1 
ATOM 709  C CB  . VAL A 1 89  ? 136.462 131.067 88.288  1.00 159.36 ? 89  VAL A CB  1 
ATOM 710  C CG1 . VAL A 1 89  ? 136.295 131.943 87.056  1.00 161.64 ? 89  VAL A CG1 1 
ATOM 711  C CG2 . VAL A 1 89  ? 137.860 131.215 88.869  1.00 157.76 ? 89  VAL A CG2 1 
ATOM 712  N N   . TYR A 1 90  ? 133.293 132.439 88.705  1.00 162.14 ? 90  TYR A N   1 
ATOM 713  C CA  . TYR A 1 90  ? 131.919 132.459 88.229  1.00 161.67 ? 90  TYR A CA  1 
ATOM 714  C C   . TYR A 1 90  ? 131.737 133.626 87.272  1.00 168.01 ? 90  TYR A C   1 
ATOM 715  O O   . TYR A 1 90  ? 132.388 134.664 87.404  1.00 168.88 ? 90  TYR A O   1 
ATOM 716  C CB  . TYR A 1 90  ? 130.919 132.559 89.391  1.00 156.07 ? 90  TYR A CB  1 
ATOM 717  C CG  . TYR A 1 90  ? 130.964 133.873 90.139  1.00 158.15 ? 90  TYR A CG  1 
ATOM 718  C CD1 . TYR A 1 90  ? 132.004 134.166 91.010  1.00 159.04 ? 90  TYR A CD1 1 
ATOM 719  C CD2 . TYR A 1 90  ? 129.958 134.816 89.980  1.00 159.19 ? 90  TYR A CD2 1 
ATOM 720  C CE1 . TYR A 1 90  ? 132.045 135.364 91.695  1.00 160.33 ? 90  TYR A CE1 1 
ATOM 721  C CE2 . TYR A 1 90  ? 129.990 136.017 90.662  1.00 159.76 ? 90  TYR A CE2 1 
ATOM 722  C CZ  . TYR A 1 90  ? 131.035 136.286 91.518  1.00 161.10 ? 90  TYR A CZ  1 
ATOM 723  O OH  . TYR A 1 90  ? 131.070 137.481 92.198  1.00 158.47 ? 90  TYR A OH  1 
ATOM 724  N N   . TYR A 1 91  ? 130.843 133.450 86.308  1.00 171.78 ? 91  TYR A N   1 
ATOM 725  C CA  . TYR A 1 91  ? 130.618 134.450 85.277  1.00 173.57 ? 91  TYR A CA  1 
ATOM 726  C C   . TYR A 1 91  ? 129.318 135.198 85.533  1.00 177.61 ? 91  TYR A C   1 
ATOM 727  O O   . TYR A 1 91  ? 128.293 134.595 85.865  1.00 177.52 ? 91  TYR A O   1 
ATOM 728  C CB  . TYR A 1 91  ? 130.580 133.810 83.889  1.00 168.90 ? 91  TYR A CB  1 
ATOM 729  C CG  . TYR A 1 91  ? 131.855 133.104 83.510  1.00 166.93 ? 91  TYR A CG  1 
ATOM 730  C CD1 . TYR A 1 91  ? 131.935 131.720 83.530  1.00 163.50 ? 91  TYR A CD1 1 
ATOM 731  C CD2 . TYR A 1 91  ? 132.981 133.820 83.135  1.00 168.48 ? 91  TYR A CD2 1 
ATOM 732  C CE1 . TYR A 1 91  ? 133.100 131.071 83.182  1.00 164.42 ? 91  TYR A CE1 1 
ATOM 733  C CE2 . TYR A 1 91  ? 134.151 133.178 82.787  1.00 169.85 ? 91  TYR A CE2 1 
ATOM 734  C CZ  . TYR A 1 91  ? 134.206 131.803 82.812  1.00 167.87 ? 91  TYR A CZ  1 
ATOM 735  O OH  . TYR A 1 91  ? 135.370 131.157 82.466  1.00 168.29 ? 91  TYR A OH  1 
ATOM 736  N N   . VAL A 1 92  ? 129.375 136.517 85.391  1.00 181.59 ? 92  VAL A N   1 
ATOM 737  C CA  . VAL A 1 92  ? 128.193 137.367 85.376  1.00 183.15 ? 92  VAL A CA  1 
ATOM 738  C C   . VAL A 1 92  ? 128.123 137.987 83.987  1.00 182.92 ? 92  VAL A C   1 
ATOM 739  O O   . VAL A 1 92  ? 128.970 138.811 83.620  1.00 182.82 ? 92  VAL A O   1 
ATOM 740  C CB  . VAL A 1 92  ? 128.236 138.434 86.478  1.00 180.06 ? 92  VAL A CB  1 
ATOM 741  C CG1 . VAL A 1 92  ? 127.047 139.369 86.345  1.00 173.63 ? 92  VAL A CG1 1 
ATOM 742  C CG2 . VAL A 1 92  ? 128.233 137.782 87.853  1.00 176.52 ? 92  VAL A CG2 1 
ATOM 743  N N   . GLY A 1 93  ? 127.118 137.590 83.212  1.00 182.61 ? 93  GLY A N   1 
ATOM 744  C CA  . GLY A 1 93  ? 127.069 137.956 81.811  1.00 184.71 ? 93  GLY A CA  1 
ATOM 745  C C   . GLY A 1 93  ? 128.248 137.382 81.053  1.00 187.26 ? 93  GLY A C   1 
ATOM 746  O O   . GLY A 1 93  ? 128.404 136.160 80.966  1.00 188.41 ? 93  GLY A O   1 
ATOM 747  N N   . ARG A 1 94  ? 129.088 138.256 80.499  1.00 186.41 ? 94  ARG A N   1 
ATOM 748  C CA  . ARG A 1 94  ? 130.340 137.842 79.884  1.00 181.99 ? 94  ARG A CA  1 
ATOM 749  C C   . ARG A 1 94  ? 131.554 138.148 80.748  1.00 181.41 ? 94  ARG A C   1 
ATOM 750  O O   . ARG A 1 94  ? 132.684 138.040 80.258  1.00 179.57 ? 94  ARG A O   1 
ATOM 751  C CB  . ARG A 1 94  ? 130.517 138.511 78.511  1.00 175.38 ? 94  ARG A CB  1 
ATOM 752  C CG  . ARG A 1 94  ? 129.512 138.070 77.459  1.00 170.56 ? 94  ARG A CG  1 
ATOM 753  C CD  . ARG A 1 94  ? 129.801 138.731 76.119  1.00 164.35 ? 94  ARG A CD  1 
ATOM 754  N NE  . ARG A 1 94  ? 128.875 138.297 75.080  1.00 161.05 ? 94  ARG A NE  1 
ATOM 755  C CZ  . ARG A 1 94  ? 128.903 138.723 73.825  1.00 158.71 ? 94  ARG A CZ  1 
ATOM 756  N NH1 . ARG A 1 94  ? 129.803 139.601 73.412  1.00 157.69 ? 94  ARG A NH1 1 
ATOM 757  N NH2 . ARG A 1 94  ? 128.005 138.258 72.961  1.00 155.81 ? 94  ARG A NH2 1 
ATOM 758  N N   . LYS A 1 95  ? 131.359 138.526 82.011  1.00 181.07 ? 95  LYS A N   1 
ATOM 759  C CA  . LYS A 1 95  ? 132.455 138.972 82.860  1.00 177.70 ? 95  LYS A CA  1 
ATOM 760  C C   . LYS A 1 95  ? 132.859 137.855 83.812  1.00 173.80 ? 95  LYS A C   1 
ATOM 761  O O   . LYS A 1 95  ? 132.028 137.417 84.622  1.00 174.61 ? 95  LYS A O   1 
ATOM 762  C CB  . LYS A 1 95  ? 132.052 140.213 83.644  1.00 176.88 ? 95  LYS A CB  1 
ATOM 763  C CG  . LYS A 1 95  ? 131.381 141.290 82.805  1.00 178.15 ? 95  LYS A CG  1 
ATOM 764  C CD  . LYS A 1 95  ? 132.257 141.719 81.636  1.00 180.56 ? 95  LYS A CD  1 
ATOM 765  C CE  . LYS A 1 95  ? 133.546 142.370 82.111  1.00 181.57 ? 95  LYS A CE  1 
ATOM 766  N NZ  . LYS A 1 95  ? 134.412 142.775 80.969  1.00 177.53 ? 95  LYS A NZ  1 
ATOM 767  N N   . PRO A 1 96  ? 134.087 137.348 83.740  1.00 171.44 ? 96  PRO A N   1 
ATOM 768  C CA  . PRO A 1 96  ? 134.566 136.430 84.778  1.00 171.77 ? 96  PRO A CA  1 
ATOM 769  C C   . PRO A 1 96  ? 134.815 137.165 86.085  1.00 175.73 ? 96  PRO A C   1 
ATOM 770  O O   . PRO A 1 96  ? 135.171 138.345 86.103  1.00 177.91 ? 96  PRO A O   1 
ATOM 771  C CB  . PRO A 1 96  ? 135.875 135.880 84.195  1.00 166.22 ? 96  PRO A CB  1 
ATOM 772  C CG  . PRO A 1 96  ? 135.849 136.244 82.737  1.00 166.42 ? 96  PRO A CG  1 
ATOM 773  C CD  . PRO A 1 96  ? 135.062 137.508 82.653  1.00 169.80 ? 96  PRO A CD  1 
ATOM 774  N N   . LYS A 1 97  ? 134.635 136.445 87.191  1.00 174.23 ? 97  LYS A N   1 
ATOM 775  C CA  . LYS A 1 97  ? 134.877 136.983 88.520  1.00 170.65 ? 97  LYS A CA  1 
ATOM 776  C C   . LYS A 1 97  ? 135.423 135.879 89.411  1.00 168.43 ? 97  LYS A C   1 
ATOM 777  O O   . LYS A 1 97  ? 134.869 134.776 89.459  1.00 166.44 ? 97  LYS A O   1 
ATOM 778  C CB  . LYS A 1 97  ? 133.597 137.565 89.138  1.00 167.49 ? 97  LYS A CB  1 
ATOM 779  C CG  . LYS A 1 97  ? 133.093 138.840 88.480  1.00 167.44 ? 97  LYS A CG  1 
ATOM 780  C CD  . LYS A 1 97  ? 134.068 139.987 88.684  1.00 170.33 ? 97  LYS A CD  1 
ATOM 781  C CE  . LYS A 1 97  ? 133.591 141.251 87.988  1.00 170.10 ? 97  LYS A CE  1 
ATOM 782  N NZ  . LYS A 1 97  ? 133.497 141.069 86.514  1.00 173.69 ? 97  LYS A NZ  1 
ATOM 783  N N   . VAL A 1 98  ? 136.504 136.186 90.121  1.00 169.00 ? 98  VAL A N   1 
ATOM 784  C CA  . VAL A 1 98  ? 137.123 135.259 91.061  1.00 166.47 ? 98  VAL A CA  1 
ATOM 785  C C   . VAL A 1 98  ? 136.719 135.667 92.470  1.00 166.26 ? 98  VAL A C   1 
ATOM 786  O O   . VAL A 1 98  ? 136.885 136.830 92.862  1.00 167.50 ? 98  VAL A O   1 
ATOM 787  C CB  . VAL A 1 98  ? 138.653 135.235 90.899  1.00 161.61 ? 98  VAL A CB  1 
ATOM 788  C CG1 . VAL A 1 98  ? 139.296 134.358 91.966  1.00 160.06 ? 98  VAL A CG1 1 
ATOM 789  C CG2 . VAL A 1 98  ? 139.032 134.755 89.507  1.00 158.94 ? 98  VAL A CG2 1 
ATOM 790  N N   . GLU A 1 99  ? 136.176 134.719 93.226  1.00 164.68 ? 99  GLU A N   1 
ATOM 791  C CA  . GLU A 1 99  ? 135.672 134.983 94.563  1.00 161.59 ? 99  GLU A CA  1 
ATOM 792  C C   . GLU A 1 99  ? 136.195 133.929 95.530  1.00 156.58 ? 99  GLU A C   1 
ATOM 793  O O   . GLU A 1 99  ? 136.624 132.845 95.131  1.00 155.16 ? 99  GLU A O   1 
ATOM 794  C CB  . GLU A 1 99  ? 134.136 135.004 94.581  1.00 160.08 ? 99  GLU A CB  1 
ATOM 795  C CG  . GLU A 1 99  ? 133.526 135.748 95.761  1.00 161.15 ? 99  GLU A CG  1 
ATOM 796  C CD  . GLU A 1 99  ? 133.752 137.247 95.694  1.00 165.96 ? 99  GLU A CD  1 
ATOM 797  O OE1 . GLU A 1 99  ? 134.053 137.759 94.595  1.00 168.68 ? 99  GLU A OE1 1 
ATOM 798  O OE2 . GLU A 1 99  ? 133.627 137.916 96.741  1.00 162.55 ? 99  GLU A OE2 1 
ATOM 799  N N   . GLN A 1 100 ? 136.177 134.270 96.813  1.00 154.57 ? 100 GLN A N   1 
ATOM 800  C CA  . GLN A 1 100 ? 136.560 133.355 97.883  1.00 151.38 ? 100 GLN A CA  1 
ATOM 801  C C   . GLN A 1 100 ? 135.335 133.158 98.768  1.00 150.89 ? 100 GLN A C   1 
ATOM 802  O O   . GLN A 1 100 ? 135.064 133.968 99.658  1.00 151.40 ? 100 GLN A O   1 
ATOM 803  C CB  . GLN A 1 100 ? 137.748 133.893 98.672  1.00 150.37 ? 100 GLN A CB  1 
ATOM 804  C CG  . GLN A 1 100 ? 138.999 134.095 97.836  1.00 153.16 ? 100 GLN A CG  1 
ATOM 805  C CD  . GLN A 1 100 ? 139.561 132.792 97.304  1.00 149.98 ? 100 GLN A CD  1 
ATOM 806  O OE1 . GLN A 1 100 ? 140.088 132.739 96.194  1.00 149.14 ? 100 GLN A OE1 1 
ATOM 807  N NE2 . GLN A 1 100 ? 139.462 131.735 98.101  1.00 146.94 ? 100 GLN A NE2 1 
ATOM 808  N N   . LEU A 1 101 ? 134.589 132.086 98.512  1.00 149.33 ? 101 LEU A N   1 
ATOM 809  C CA  . LEU A 1 101 ? 133.432 131.776 99.340  1.00 144.64 ? 101 LEU A CA  1 
ATOM 810  C C   . LEU A 1 101 ? 133.880 131.477 100.760 1.00 140.83 ? 101 LEU A C   1 
ATOM 811  O O   . LEU A 1 101 ? 134.580 130.490 101.005 1.00 139.75 ? 101 LEU A O   1 
ATOM 812  C CB  . LEU A 1 101 ? 132.667 130.588 98.764  1.00 141.62 ? 101 LEU A CB  1 
ATOM 813  C CG  . LEU A 1 101 ? 131.673 130.865 97.639  1.00 142.16 ? 101 LEU A CG  1 
ATOM 814  C CD1 . LEU A 1 101 ? 130.876 129.610 97.326  1.00 133.39 ? 101 LEU A CD1 1 
ATOM 815  C CD2 . LEU A 1 101 ? 130.752 132.016 98.008  1.00 142.14 ? 101 LEU A CD2 1 
ATOM 816  N N   . SER A 1 102 ? 133.481 132.333 101.695 1.00 138.06 ? 102 SER A N   1 
ATOM 817  C CA  . SER A 1 102 ? 133.924 132.190 103.073 1.00 134.19 ? 102 SER A CA  1 
ATOM 818  C C   . SER A 1 102 ? 133.355 130.922 103.697 1.00 128.26 ? 102 SER A C   1 
ATOM 819  O O   . SER A 1 102 ? 132.193 130.572 103.481 1.00 128.08 ? 102 SER A O   1 
ATOM 820  C CB  . SER A 1 102 ? 133.507 133.410 103.892 1.00 135.34 ? 102 SER A CB  1 
ATOM 821  O OG  . SER A 1 102 ? 134.057 134.600 103.355 1.00 139.06 ? 102 SER A OG  1 
ATOM 822  N N   . ASN A 1 103 ? 134.193 130.230 104.465 1.00 125.03 ? 103 ASN A N   1 
ATOM 823  C CA  . ASN A 1 103 ? 133.774 129.107 105.298 1.00 121.92 ? 103 ASN A CA  1 
ATOM 824  C C   . ASN A 1 103 ? 133.114 128.009 104.466 1.00 118.55 ? 103 ASN A C   1 
ATOM 825  O O   . ASN A 1 103 ? 131.923 127.729 104.588 1.00 123.75 ? 103 ASN A O   1 
ATOM 826  C CB  . ASN A 1 103 ? 132.842 129.585 106.413 1.00 122.02 ? 103 ASN A CB  1 
ATOM 827  C CG  . ASN A 1 103 ? 133.408 130.760 107.179 1.00 121.90 ? 103 ASN A CG  1 
ATOM 828  O OD1 . ASN A 1 103 ? 134.621 130.880 107.348 1.00 120.71 ? 103 ASN A OD1 1 
ATOM 829  N ND2 . ASN A 1 103 ? 132.531 131.640 107.645 1.00 122.92 ? 103 ASN A ND2 1 
ATOM 830  N N   . MET A 1 104 ? 133.910 127.394 103.593 1.00 115.32 ? 104 MET A N   1 
ATOM 831  C CA  . MET A 1 104 ? 133.419 126.303 102.766 1.00 115.23 ? 104 MET A CA  1 
ATOM 832  C C   . MET A 1 104 ? 134.144 124.985 102.979 1.00 118.77 ? 104 MET A C   1 
ATOM 833  O O   . MET A 1 104 ? 133.583 123.935 102.652 1.00 119.23 ? 104 MET A O   1 
ATOM 834  C CB  . MET A 1 104 ? 133.514 126.678 101.283 1.00 122.52 ? 104 MET A CB  1 
ATOM 835  C CG  . MET A 1 104 ? 132.602 127.810 100.889 1.00 125.75 ? 104 MET A CG  1 
ATOM 836  S SD  . MET A 1 104 ? 130.927 127.249 100.565 1.00 123.75 ? 104 MET A SD  1 
ATOM 837  C CE  . MET A 1 104 ? 131.219 126.144 99.190  1.00 115.76 ? 104 MET A CE  1 
ATOM 838  N N   . ILE A 1 105 ? 135.362 125.005 103.512 1.00 123.88 ? 105 ILE A N   1 
ATOM 839  C CA  . ILE A 1 105 ? 136.184 123.811 103.656 1.00 119.56 ? 105 ILE A CA  1 
ATOM 840  C C   . ILE A 1 105 ? 136.507 123.621 105.130 1.00 113.87 ? 105 ILE A C   1 
ATOM 841  O O   . ILE A 1 105 ? 136.920 124.569 105.807 1.00 113.92 ? 105 ILE A O   1 
ATOM 842  C CB  . ILE A 1 105 ? 137.475 123.911 102.824 1.00 122.82 ? 105 ILE A CB  1 
ATOM 843  C CG1 . ILE A 1 105 ? 137.147 124.272 101.374 1.00 126.10 ? 105 ILE A CG1 1 
ATOM 844  C CG2 . ILE A 1 105 ? 138.246 122.606 102.884 1.00 120.18 ? 105 ILE A CG2 1 
ATOM 845  C CD1 . ILE A 1 105 ? 138.364 124.409 100.492 1.00 128.64 ? 105 ILE A CD1 1 
ATOM 846  N N   . VAL A 1 106 ? 136.321 122.401 105.621 1.00 107.75 ? 106 VAL A N   1 
ATOM 847  C CA  . VAL A 1 106 ? 136.594 122.054 107.010 1.00 106.73 ? 106 VAL A CA  1 
ATOM 848  C C   . VAL A 1 106 ? 138.035 121.579 107.112 1.00 115.52 ? 106 VAL A C   1 
ATOM 849  O O   . VAL A 1 106 ? 138.453 120.675 106.379 1.00 119.28 ? 106 VAL A O   1 
ATOM 850  C CB  . VAL A 1 106 ? 135.623 120.980 107.521 1.00 101.60 ? 106 VAL A CB  1 
ATOM 851  C CG1 . VAL A 1 106 ? 136.239 120.205 108.668 1.00 100.07 ? 106 VAL A CG1 1 
ATOM 852  C CG2 . VAL A 1 106 ? 134.332 121.617 107.962 1.00 103.39 ? 106 VAL A CG2 1 
ATOM 853  N N   . ARG A 1 107 ? 138.798 122.188 108.021 1.00 117.70 ? 107 ARG A N   1 
ATOM 854  C CA  . ARG A 1 107 ? 140.172 121.781 108.268 1.00 118.96 ? 107 ARG A CA  1 
ATOM 855  C C   . ARG A 1 107 ? 140.386 121.154 109.636 1.00 116.71 ? 107 ARG A C   1 
ATOM 856  O O   . ARG A 1 107 ? 141.242 120.275 109.765 1.00 119.30 ? 107 ARG A O   1 
ATOM 857  C CB  . ARG A 1 107 ? 141.119 122.979 108.113 1.00 120.96 ? 107 ARG A CB  1 
ATOM 858  C CG  . ARG A 1 107 ? 142.592 122.608 108.130 1.00 122.15 ? 107 ARG A CG  1 
ATOM 859  C CD  . ARG A 1 107 ? 143.452 123.754 107.637 1.00 126.42 ? 107 ARG A CD  1 
ATOM 860  N NE  . ARG A 1 107 ? 142.998 124.240 106.340 1.00 132.91 ? 107 ARG A NE  1 
ATOM 861  C CZ  . ARG A 1 107 ? 143.313 123.683 105.179 1.00 135.97 ? 107 ARG A CZ  1 
ATOM 862  N NH1 . ARG A 1 107 ? 144.089 122.614 105.113 1.00 137.63 ? 107 ARG A NH1 1 
ATOM 863  N NH2 . ARG A 1 107 ? 142.835 124.211 104.056 1.00 133.65 ? 107 ARG A NH2 1 
ATOM 864  N N   . SER A 1 108 ? 139.635 121.572 110.651 1.00 112.40 ? 108 SER A N   1 
ATOM 865  C CA  . SER A 1 108 ? 139.757 121.008 111.985 1.00 109.79 ? 108 SER A CA  1 
ATOM 866  C C   . SER A 1 108 ? 138.371 120.816 112.581 1.00 102.13 ? 108 SER A C   1 
ATOM 867  O O   . SER A 1 108 ? 137.435 121.554 112.265 1.00 105.11 ? 108 SER A O   1 
ATOM 868  C CB  . SER A 1 108 ? 140.603 121.901 112.900 1.00 113.17 ? 108 SER A CB  1 
ATOM 869  O OG  . SER A 1 108 ? 141.909 122.070 112.379 1.00 121.67 ? 108 SER A OG  1 
ATOM 870  N N   . CYS A 1 109 ? 138.250 119.828 113.458 1.00 93.88  ? 109 CYS A N   1 
ATOM 871  C CA  . CYS A 1 109 ? 136.987 119.516 114.106 1.00 88.38  ? 109 CYS A CA  1 
ATOM 872  C C   . CYS A 1 109 ? 137.168 119.465 115.615 1.00 94.80  ? 109 CYS A C   1 
ATOM 873  O O   . CYS A 1 109 ? 138.167 118.940 116.115 1.00 103.69 ? 109 CYS A O   1 
ATOM 874  C CB  . CYS A 1 109 ? 136.431 118.192 113.604 1.00 87.61  ? 109 CYS A CB  1 
ATOM 875  S SG  . CYS A 1 109 ? 136.207 118.151 111.823 1.00 125.30 ? 109 CYS A SG  1 
ATOM 876  N N   . LYS A 1 110 ? 136.194 120.014 116.333 1.00 89.35  ? 110 LYS A N   1 
ATOM 877  C CA  . LYS A 1 110 ? 136.178 120.020 117.786 1.00 78.99  ? 110 LYS A CA  1 
ATOM 878  C C   . LYS A 1 110 ? 134.947 119.265 118.263 1.00 76.38  ? 110 LYS A C   1 
ATOM 879  O O   . LYS A 1 110 ? 134.098 118.857 117.470 1.00 87.76  ? 110 LYS A O   1 
ATOM 880  C CB  . LYS A 1 110 ? 136.177 121.451 118.334 1.00 78.71  ? 110 LYS A CB  1 
ATOM 881  C CG  . LYS A 1 110 ? 134.959 122.251 117.921 1.00 79.82  ? 110 LYS A CG  1 
ATOM 882  C CD  . LYS A 1 110 ? 135.101 123.717 118.279 1.00 78.60  ? 110 LYS A CD  1 
ATOM 883  C CE  . LYS A 1 110 ? 133.854 124.493 117.895 1.00 80.20  ? 110 LYS A CE  1 
ATOM 884  N NZ  . LYS A 1 110 ? 134.013 125.951 118.127 1.00 86.61  ? 110 LYS A NZ  1 
ATOM 885  N N   . CYS A 1 111 ? 134.855 119.070 119.572 1.00 66.03  ? 111 CYS A N   1 
ATOM 886  C CA  . CYS A 1 111 ? 133.691 118.452 120.190 1.00 67.39  ? 111 CYS A CA  1 
ATOM 887  C C   . CYS A 1 111 ? 132.945 119.515 120.982 1.00 73.79  ? 111 CYS A C   1 
ATOM 888  O O   . CYS A 1 111 ? 133.548 120.220 121.796 1.00 77.13  ? 111 CYS A O   1 
ATOM 889  C CB  . CYS A 1 111 ? 134.103 117.296 121.097 1.00 65.61  ? 111 CYS A CB  1 
ATOM 890  S SG  . CYS A 1 111 ? 134.790 115.870 120.251 1.00 78.96  ? 111 CYS A SG  1 
ATOM 891  N N   . SER A 1 112 ? 131.644 119.634 120.745 1.00 75.40  ? 112 SER A N   1 
ATOM 892  C CA  . SER A 1 112 ? 130.849 120.637 121.443 1.00 77.27  ? 112 SER A CA  1 
ATOM 893  C C   . SER A 1 112 ? 129.550 120.052 121.974 1.00 73.73  ? 112 SER A C   1 
ATOM 894  O O   . SER A 1 112 ? 128.739 119.531 121.214 1.00 74.53  ? 112 SER A O   1 
ATOM 895  C CB  . SER A 1 112 ? 130.553 121.819 120.521 1.00 83.31  ? 112 SER A CB  1 
ATOM 896  O OG  . SER A 1 112 ? 131.746 122.476 120.137 1.00 80.13  ? 112 SER A OG  1 
ATOM 897  N N   . ALA B 1 1   ? 119.003 132.474 118.642 1.00 121.40 ? 1   ALA B N   1 
ATOM 898  C CA  . ALA B 1 1   ? 117.671 132.453 118.050 1.00 129.91 ? 1   ALA B CA  1 
ATOM 899  C C   . ALA B 1 1   ? 116.832 131.329 118.643 1.00 127.25 ? 1   ALA B C   1 
ATOM 900  O O   . ALA B 1 1   ? 115.675 131.535 119.008 1.00 123.91 ? 1   ALA B O   1 
ATOM 901  C CB  . ALA B 1 1   ? 117.762 132.306 116.539 1.00 125.85 ? 1   ALA B CB  1 
ATOM 902  N N   . LEU B 1 2   ? 117.421 130.136 118.735 1.00 121.42 ? 2   LEU B N   1 
ATOM 903  C CA  . LEU B 1 2   ? 116.724 128.965 119.264 1.00 118.48 ? 2   LEU B CA  1 
ATOM 904  C C   . LEU B 1 2   ? 116.957 128.837 120.771 1.00 116.45 ? 2   LEU B C   1 
ATOM 905  O O   . LEU B 1 2   ? 117.343 127.790 121.288 1.00 116.09 ? 2   LEU B O   1 
ATOM 906  C CB  . LEU B 1 2   ? 117.173 127.710 118.529 1.00 116.59 ? 2   LEU B CB  1 
ATOM 907  C CG  . LEU B 1 2   ? 116.970 127.692 117.014 1.00 116.71 ? 2   LEU B CG  1 
ATOM 908  C CD1 . LEU B 1 2   ? 117.556 126.426 116.419 1.00 108.09 ? 2   LEU B CD1 1 
ATOM 909  C CD2 . LEU B 1 2   ? 115.494 127.814 116.669 1.00 114.99 ? 2   LEU B CD2 1 
ATOM 910  N N   . ASP B 1 3   ? 116.686 129.930 121.478 1.00 119.91 ? 3   ASP B N   1 
ATOM 911  C CA  . ASP B 1 3   ? 116.958 130.007 122.904 1.00 114.42 ? 3   ASP B CA  1 
ATOM 912  C C   . ASP B 1 3   ? 116.060 129.050 123.684 1.00 111.73 ? 3   ASP B C   1 
ATOM 913  O O   . ASP B 1 3   ? 115.186 128.378 123.131 1.00 113.27 ? 3   ASP B O   1 
ATOM 914  C CB  . ASP B 1 3   ? 116.777 131.440 123.404 1.00 112.36 ? 3   ASP B CB  1 
ATOM 915  C CG  . ASP B 1 3   ? 115.366 131.953 123.205 1.00 121.99 ? 3   ASP B CG  1 
ATOM 916  O OD1 . ASP B 1 3   ? 114.545 131.223 122.609 1.00 123.50 ? 3   ASP B OD1 1 
ATOM 917  O OD2 . ASP B 1 3   ? 115.075 133.086 123.639 1.00 120.48 ? 3   ASP B OD2 1 
ATOM 918  N N   . THR B 1 4   ? 116.298 128.985 124.996 1.00 105.82 ? 4   THR B N   1 
ATOM 919  C CA  . THR B 1 4   ? 115.499 128.112 125.848 1.00 103.50 ? 4   THR B CA  1 
ATOM 920  C C   . THR B 1 4   ? 114.038 128.530 125.858 1.00 111.16 ? 4   THR B C   1 
ATOM 921  O O   . THR B 1 4   ? 113.153 127.681 126.001 1.00 112.07 ? 4   THR B O   1 
ATOM 922  C CB  . THR B 1 4   ? 116.048 128.108 127.275 1.00 99.92  ? 4   THR B CB  1 
ATOM 923  O OG1 . THR B 1 4   ? 116.039 129.443 127.795 1.00 108.79 ? 4   THR B OG1 1 
ATOM 924  C CG2 . THR B 1 4   ? 117.466 127.576 127.300 1.00 92.92  ? 4   THR B CG2 1 
ATOM 925  N N   . ASN B 1 5   ? 113.765 129.826 125.702 1.00 116.19 ? 5   ASN B N   1 
ATOM 926  C CA  . ASN B 1 5   ? 112.388 130.306 125.730 1.00 115.46 ? 5   ASN B CA  1 
ATOM 927  C C   . ASN B 1 5   ? 111.553 129.635 124.647 1.00 120.38 ? 5   ASN B C   1 
ATOM 928  O O   . ASN B 1 5   ? 110.496 129.059 124.927 1.00 123.95 ? 5   ASN B O   1 
ATOM 929  C CB  . ASN B 1 5   ? 112.364 131.826 125.566 1.00 109.89 ? 5   ASN B CB  1 
ATOM 930  C CG  . ASN B 1 5   ? 113.228 132.534 126.587 1.00 110.05 ? 5   ASN B CG  1 
ATOM 931  O OD1 . ASN B 1 5   ? 113.419 132.047 127.700 1.00 106.84 ? 5   ASN B OD1 1 
ATOM 932  N ND2 . ASN B 1 5   ? 113.758 133.692 126.212 1.00 113.41 ? 5   ASN B ND2 1 
ATOM 933  N N   . TYR B 1 6   ? 112.027 129.677 123.400 1.00 120.17 ? 6   TYR B N   1 
ATOM 934  C CA  . TYR B 1 6   ? 111.263 129.089 122.305 1.00 120.22 ? 6   TYR B CA  1 
ATOM 935  C C   . TYR B 1 6   ? 111.176 127.574 122.435 1.00 121.54 ? 6   TYR B C   1 
ATOM 936  O O   . TYR B 1 6   ? 110.103 126.990 122.242 1.00 123.41 ? 6   TYR B O   1 
ATOM 937  C CB  . TYR B 1 6   ? 111.880 129.470 120.961 1.00 117.36 ? 6   TYR B CB  1 
ATOM 938  C CG  . TYR B 1 6   ? 111.228 128.772 119.788 1.00 124.91 ? 6   TYR B CG  1 
ATOM 939  C CD1 . TYR B 1 6   ? 109.997 129.193 119.302 1.00 126.56 ? 6   TYR B CD1 1 
ATOM 940  C CD2 . TYR B 1 6   ? 111.838 127.690 119.171 1.00 126.84 ? 6   TYR B CD2 1 
ATOM 941  C CE1 . TYR B 1 6   ? 109.395 128.557 118.234 1.00 127.34 ? 6   TYR B CE1 1 
ATOM 942  C CE2 . TYR B 1 6   ? 111.243 127.047 118.103 1.00 128.99 ? 6   TYR B CE2 1 
ATOM 943  C CZ  . TYR B 1 6   ? 110.023 127.485 117.638 1.00 130.33 ? 6   TYR B CZ  1 
ATOM 944  O OH  . TYR B 1 6   ? 109.428 126.849 116.574 1.00 127.73 ? 6   TYR B OH  1 
ATOM 945  N N   . CYS B 1 7   ? 112.294 126.918 122.751 1.00 115.32 ? 7   CYS B N   1 
ATOM 946  C CA  . CYS B 1 7   ? 112.303 125.459 122.792 1.00 112.46 ? 7   CYS B CA  1 
ATOM 947  C C   . CYS B 1 7   ? 111.407 124.925 123.901 1.00 115.11 ? 7   CYS B C   1 
ATOM 948  O O   . CYS B 1 7   ? 110.666 123.956 123.696 1.00 118.36 ? 7   CYS B O   1 
ATOM 949  C CB  . CYS B 1 7   ? 113.731 124.949 122.958 1.00 105.74 ? 7   CYS B CB  1 
ATOM 950  S SG  . CYS B 1 7   ? 114.832 125.400 121.604 1.00 129.19 ? 7   CYS B SG  1 
ATOM 951  N N   . PHE B 1 8   ? 111.456 125.537 125.084 1.00 115.83 ? 8   PHE B N   1 
ATOM 952  C CA  . PHE B 1 8   ? 110.599 125.081 126.171 1.00 116.61 ? 8   PHE B CA  1 
ATOM 953  C C   . PHE B 1 8   ? 109.163 125.553 125.977 1.00 121.27 ? 8   PHE B C   1 
ATOM 954  O O   . PHE B 1 8   ? 108.230 124.959 126.530 1.00 124.62 ? 8   PHE B O   1 
ATOM 955  C CB  . PHE B 1 8   ? 111.152 125.559 127.514 1.00 112.20 ? 8   PHE B CB  1 
ATOM 956  C CG  . PHE B 1 8   ? 112.450 124.905 127.901 1.00 110.94 ? 8   PHE B CG  1 
ATOM 957  C CD1 . PHE B 1 8   ? 112.534 123.530 128.029 1.00 110.17 ? 8   PHE B CD1 1 
ATOM 958  C CD2 . PHE B 1 8   ? 113.581 125.663 128.148 1.00 100.37 ? 8   PHE B CD2 1 
ATOM 959  C CE1 . PHE B 1 8   ? 113.720 122.926 128.385 1.00 97.70  ? 8   PHE B CE1 1 
ATOM 960  C CE2 . PHE B 1 8   ? 114.766 125.063 128.505 1.00 92.64  ? 8   PHE B CE2 1 
ATOM 961  C CZ  . PHE B 1 8   ? 114.836 123.692 128.624 1.00 92.47  ? 8   PHE B CZ  1 
ATOM 962  N N   . SER B 1 9   ? 108.965 126.617 125.195 1.00 124.61 ? 9   SER B N   1 
ATOM 963  C CA  . SER B 1 9   ? 107.619 127.117 124.945 1.00 127.62 ? 9   SER B CA  1 
ATOM 964  C C   . SER B 1 9   ? 106.796 126.172 124.083 1.00 129.85 ? 9   SER B C   1 
ATOM 965  O O   . SER B 1 9   ? 105.606 125.982 124.354 1.00 132.00 ? 9   SER B O   1 
ATOM 966  C CB  . SER B 1 9   ? 107.686 128.492 124.280 1.00 128.02 ? 9   SER B CB  1 
ATOM 967  O OG  . SER B 1 9   ? 106.400 128.918 123.867 1.00 127.35 ? 9   SER B OG  1 
ATOM 968  N N   . SER B 1 10  ? 107.397 125.577 123.056 1.00 128.93 ? 10  SER B N   1 
ATOM 969  C CA  . SER B 1 10  ? 106.664 124.696 122.160 1.00 131.19 ? 10  SER B CA  1 
ATOM 970  C C   . SER B 1 10  ? 107.579 123.561 121.730 1.00 130.00 ? 10  SER B C   1 
ATOM 971  O O   . SER B 1 10  ? 108.758 123.783 121.443 1.00 126.07 ? 10  SER B O   1 
ATOM 972  C CB  . SER B 1 10  ? 106.142 125.456 120.935 1.00 127.92 ? 10  SER B CB  1 
ATOM 973  O OG  . SER B 1 10  ? 105.297 126.526 121.321 1.00 127.37 ? 10  SER B OG  1 
ATOM 974  N N   . THR B 1 11  ? 107.027 122.352 121.689 1.00 133.53 ? 11  THR B N   1 
ATOM 975  C CA  . THR B 1 11  ? 107.802 121.188 121.287 1.00 132.24 ? 11  THR B CA  1 
ATOM 976  C C   . THR B 1 11  ? 108.225 121.309 119.829 1.00 130.44 ? 11  THR B C   1 
ATOM 977  O O   . THR B 1 11  ? 107.413 121.619 118.953 1.00 130.71 ? 11  THR B O   1 
ATOM 978  C CB  . THR B 1 11  ? 106.990 119.911 121.494 1.00 134.33 ? 11  THR B CB  1 
ATOM 979  O OG1 . THR B 1 11  ? 106.624 119.798 122.875 1.00 136.74 ? 11  THR B OG1 1 
ATOM 980  C CG2 . THR B 1 11  ? 107.803 118.690 121.092 1.00 126.06 ? 11  THR B CG2 1 
ATOM 981  N N   . GLU B 1 12  ? 109.507 121.060 119.573 1.00 126.66 ? 12  GLU B N   1 
ATOM 982  C CA  . GLU B 1 12  ? 110.061 121.168 118.227 1.00 126.23 ? 12  GLU B CA  1 
ATOM 983  C C   . GLU B 1 12  ? 110.879 119.915 117.957 1.00 126.18 ? 12  GLU B C   1 
ATOM 984  O O   . GLU B 1 12  ? 111.746 119.558 118.759 1.00 127.37 ? 12  GLU B O   1 
ATOM 985  C CB  . GLU B 1 12  ? 110.917 122.422 118.084 1.00 122.48 ? 12  GLU B CB  1 
ATOM 986  C CG  . GLU B 1 12  ? 110.140 123.714 118.220 1.00 125.89 ? 12  GLU B CG  1 
ATOM 987  C CD  . GLU B 1 12  ? 109.020 123.823 117.206 1.00 135.37 ? 12  GLU B CD  1 
ATOM 988  O OE1 . GLU B 1 12  ? 109.230 123.428 116.041 1.00 142.41 ? 12  GLU B OE1 1 
ATOM 989  O OE2 . GLU B 1 12  ? 107.928 124.307 117.571 1.00 132.17 ? 12  GLU B OE2 1 
ATOM 990  N N   . LYS B 1 13  ? 110.602 119.246 116.839 1.00 124.91 ? 13  LYS B N   1 
ATOM 991  C CA  . LYS B 1 13  ? 111.365 118.059 116.476 1.00 123.25 ? 13  LYS B CA  1 
ATOM 992  C C   . LYS B 1 13  ? 112.768 118.387 115.988 1.00 122.19 ? 13  LYS B C   1 
ATOM 993  O O   . LYS B 1 13  ? 113.590 117.472 115.870 1.00 120.67 ? 13  LYS B O   1 
ATOM 994  C CB  . LYS B 1 13  ? 110.620 117.264 115.402 1.00 119.18 ? 13  LYS B CB  1 
ATOM 995  C CG  . LYS B 1 13  ? 109.213 116.858 115.801 1.00 120.06 ? 13  LYS B CG  1 
ATOM 996  C CD  . LYS B 1 13  ? 108.530 116.072 114.697 1.00 116.91 ? 13  LYS B CD  1 
ATOM 997  C CE  . LYS B 1 13  ? 107.116 115.683 115.095 1.00 115.99 ? 13  LYS B CE  1 
ATOM 998  N NZ  . LYS B 1 13  ? 107.094 114.871 116.342 1.00 114.73 ? 13  LYS B NZ  1 
ATOM 999  N N   . ASN B 1 14  ? 113.061 119.654 115.707 1.00 120.83 ? 14  ASN B N   1 
ATOM 1000 C CA  . ASN B 1 14  ? 114.342 120.038 115.142 1.00 116.44 ? 14  ASN B CA  1 
ATOM 1001 C C   . ASN B 1 14  ? 115.351 120.364 116.241 1.00 117.44 ? 14  ASN B C   1 
ATOM 1002 O O   . ASN B 1 14  ? 115.134 120.103 117.427 1.00 122.11 ? 14  ASN B O   1 
ATOM 1003 C CB  . ASN B 1 14  ? 114.176 121.233 114.208 1.00 116.36 ? 14  ASN B CB  1 
ATOM 1004 C CG  . ASN B 1 14  ? 113.465 120.872 112.922 1.00 127.30 ? 14  ASN B CG  1 
ATOM 1005 O OD1 . ASN B 1 14  ? 113.455 119.713 112.511 1.00 126.61 ? 14  ASN B OD1 1 
ATOM 1006 N ND2 . ASN B 1 14  ? 112.862 121.865 112.282 1.00 132.11 ? 14  ASN B ND2 1 
ATOM 1007 N N   . CYS B 1 15  ? 116.475 120.946 115.823 1.00 112.39 ? 15  CYS B N   1 
ATOM 1008 C CA  . CYS B 1 15  ? 117.557 121.301 116.732 1.00 103.72 ? 15  CYS B CA  1 
ATOM 1009 C C   . CYS B 1 15  ? 117.100 122.318 117.765 1.00 100.67 ? 15  CYS B C   1 
ATOM 1010 O O   . CYS B 1 15  ? 116.862 123.484 117.439 1.00 103.16 ? 15  CYS B O   1 
ATOM 1011 C CB  . CYS B 1 15  ? 118.748 121.841 115.940 1.00 103.15 ? 15  CYS B CB  1 
ATOM 1012 S SG  . CYS B 1 15  ? 120.034 122.660 116.901 1.00 104.18 ? 15  CYS B SG  1 
ATOM 1013 N N   . CYS B 1 16  ? 116.988 121.882 119.015 1.00 93.31  ? 16  CYS B N   1 
ATOM 1014 C CA  . CYS B 1 16  ? 116.538 122.744 120.093 1.00 89.07  ? 16  CYS B CA  1 
ATOM 1015 C C   . CYS B 1 16  ? 117.223 122.317 121.380 1.00 89.70  ? 16  CYS B C   1 
ATOM 1016 O O   . CYS B 1 16  ? 117.754 121.207 121.487 1.00 92.29  ? 16  CYS B O   1 
ATOM 1017 C CB  . CYS B 1 16  ? 115.017 122.693 120.259 1.00 94.59  ? 16  CYS B CB  1 
ATOM 1018 S SG  . CYS B 1 16  ? 114.190 124.281 120.037 1.00 124.36 ? 16  CYS B SG  1 
ATOM 1019 N N   . VAL B 1 17  ? 117.222 123.222 122.351 1.00 87.53  ? 17  VAL B N   1 
ATOM 1020 C CA  . VAL B 1 17  ? 117.728 122.910 123.681 1.00 76.93  ? 17  VAL B CA  1 
ATOM 1021 C C   . VAL B 1 17  ? 116.665 122.124 124.431 1.00 81.83  ? 17  VAL B C   1 
ATOM 1022 O O   . VAL B 1 17  ? 115.468 122.415 124.332 1.00 96.15  ? 17  VAL B O   1 
ATOM 1023 C CB  . VAL B 1 17  ? 118.126 124.197 124.426 1.00 71.34  ? 17  VAL B CB  1 
ATOM 1024 C CG1 . VAL B 1 17  ? 117.827 125.414 123.582 1.00 84.66  ? 17  VAL B CG1 1 
ATOM 1025 C CG2 . VAL B 1 17  ? 117.423 124.294 125.755 1.00 79.60  ? 17  VAL B CG2 1 
ATOM 1026 N N   . ARG B 1 18  ? 117.093 121.098 125.155 1.00 79.18  ? 18  ARG B N   1 
ATOM 1027 C CA  . ARG B 1 18  ? 116.195 120.270 125.937 1.00 86.86  ? 18  ARG B CA  1 
ATOM 1028 C C   . ARG B 1 18  ? 116.662 120.275 127.384 1.00 91.89  ? 18  ARG B C   1 
ATOM 1029 O O   . ARG B 1 18  ? 117.863 120.339 127.664 1.00 94.56  ? 18  ARG B O   1 
ATOM 1030 C CB  . ARG B 1 18  ? 116.145 118.837 125.395 1.00 83.76  ? 18  ARG B CB  1 
ATOM 1031 C CG  . ARG B 1 18  ? 114.881 118.077 125.752 1.00 95.51  ? 18  ARG B CG  1 
ATOM 1032 C CD  . ARG B 1 18  ? 113.658 118.747 125.150 1.00 106.41 ? 18  ARG B CD  1 
ATOM 1033 N NE  . ARG B 1 18  ? 112.430 118.010 125.418 1.00 112.91 ? 18  ARG B NE  1 
ATOM 1034 C CZ  . ARG B 1 18  ? 111.226 118.400 125.024 1.00 118.67 ? 18  ARG B CZ  1 
ATOM 1035 N NH1 . ARG B 1 18  ? 111.051 119.522 124.346 1.00 120.92 ? 18  ARG B NH1 1 
ATOM 1036 N NH2 . ARG B 1 18  ? 110.170 117.645 125.317 1.00 120.09 ? 18  ARG B NH2 1 
ATOM 1037 N N   . GLN B 1 19  ? 115.701 120.221 128.301 1.00 93.33  ? 19  GLN B N   1 
ATOM 1038 C CA  . GLN B 1 19  ? 116.027 120.267 129.718 1.00 90.18  ? 19  GLN B CA  1 
ATOM 1039 C C   . GLN B 1 19  ? 116.790 119.015 130.127 1.00 85.80  ? 19  GLN B C   1 
ATOM 1040 O O   . GLN B 1 19  ? 116.503 117.908 129.662 1.00 83.25  ? 19  GLN B O   1 
ATOM 1041 C CB  . GLN B 1 19  ? 114.758 120.419 130.562 1.00 91.97  ? 19  GLN B CB  1 
ATOM 1042 C CG  . GLN B 1 19  ? 113.898 119.166 130.696 1.00 96.53  ? 19  GLN B CG  1 
ATOM 1043 C CD  . GLN B 1 19  ? 113.108 118.849 129.441 1.00 106.16 ? 19  GLN B CD  1 
ATOM 1044 O OE1 . GLN B 1 19  ? 113.049 119.651 128.510 1.00 107.28 ? 19  GLN B OE1 1 
ATOM 1045 N NE2 . GLN B 1 19  ? 112.491 117.674 129.413 1.00 109.28 ? 19  GLN B NE2 1 
ATOM 1046 N N   . LEU B 1 20  ? 117.783 119.202 130.992 1.00 79.44  ? 20  LEU B N   1 
ATOM 1047 C CA  . LEU B 1 20  ? 118.586 118.099 131.499 1.00 76.96  ? 20  LEU B CA  1 
ATOM 1048 C C   . LEU B 1 20  ? 119.122 118.484 132.867 1.00 79.16  ? 20  LEU B C   1 
ATOM 1049 O O   . LEU B 1 20  ? 119.624 119.597 133.044 1.00 78.85  ? 20  LEU B O   1 
ATOM 1050 C CB  . LEU B 1 20  ? 119.736 117.770 130.546 1.00 67.23  ? 20  LEU B CB  1 
ATOM 1051 C CG  . LEU B 1 20  ? 120.694 116.675 131.001 1.00 66.68  ? 20  LEU B CG  1 
ATOM 1052 C CD1 . LEU B 1 20  ? 119.959 115.360 131.115 1.00 64.70  ? 20  LEU B CD1 1 
ATOM 1053 C CD2 . LEU B 1 20  ? 121.861 116.562 130.044 1.00 70.69  ? 20  LEU B CD2 1 
ATOM 1054 N N   . TYR B 1 21  ? 119.013 117.573 133.825 1.00 78.43  ? 21  TYR B N   1 
ATOM 1055 C CA  . TYR B 1 21  ? 119.476 117.813 135.184 1.00 75.19  ? 21  TYR B CA  1 
ATOM 1056 C C   . TYR B 1 21  ? 120.790 117.077 135.393 1.00 77.56  ? 21  TYR B C   1 
ATOM 1057 O O   . TYR B 1 21  ? 120.801 115.851 135.538 1.00 82.83  ? 21  TYR B O   1 
ATOM 1058 C CB  . TYR B 1 21  ? 118.439 117.359 136.209 1.00 75.56  ? 21  TYR B CB  1 
ATOM 1059 C CG  . TYR B 1 21  ? 118.740 117.816 137.617 1.00 74.46  ? 21  TYR B CG  1 
ATOM 1060 C CD1 . TYR B 1 21  ? 118.442 119.107 138.023 1.00 70.42  ? 21  TYR B CD1 1 
ATOM 1061 C CD2 . TYR B 1 21  ? 119.318 116.958 138.538 1.00 76.28  ? 21  TYR B CD2 1 
ATOM 1062 C CE1 . TYR B 1 21  ? 118.712 119.532 139.303 1.00 69.47  ? 21  TYR B CE1 1 
ATOM 1063 C CE2 . TYR B 1 21  ? 119.591 117.375 139.823 1.00 80.37  ? 21  TYR B CE2 1 
ATOM 1064 C CZ  . TYR B 1 21  ? 119.286 118.664 140.200 1.00 75.10  ? 21  TYR B CZ  1 
ATOM 1065 O OH  . TYR B 1 21  ? 119.555 119.088 141.479 1.00 73.05  ? 21  TYR B OH  1 
ATOM 1066 N N   . ILE B 1 22  ? 121.887 117.824 135.413 1.00 72.70  ? 22  ILE B N   1 
ATOM 1067 C CA  . ILE B 1 22  ? 123.204 117.270 135.688 1.00 75.24  ? 22  ILE B CA  1 
ATOM 1068 C C   . ILE B 1 22  ? 123.390 117.255 137.196 1.00 81.63  ? 22  ILE B C   1 
ATOM 1069 O O   . ILE B 1 22  ? 123.485 118.315 137.829 1.00 79.80  ? 22  ILE B O   1 
ATOM 1070 C CB  . ILE B 1 22  ? 124.310 118.082 135.000 1.00 75.87  ? 22  ILE B CB  1 
ATOM 1071 C CG1 . ILE B 1 22  ? 124.308 117.813 133.501 1.00 76.21  ? 22  ILE B CG1 1 
ATOM 1072 C CG2 . ILE B 1 22  ? 125.652 117.724 135.572 1.00 73.01  ? 22  ILE B CG2 1 
ATOM 1073 C CD1 . ILE B 1 22  ? 124.591 116.382 133.164 1.00 80.53  ? 22  ILE B CD1 1 
ATOM 1074 N N   . ASP B 1 23  ? 123.420 116.058 137.773 1.00 83.48  ? 23  ASP B N   1 
ATOM 1075 C CA  . ASP B 1 23  ? 123.576 115.873 139.209 1.00 80.47  ? 23  ASP B CA  1 
ATOM 1076 C C   . ASP B 1 23  ? 125.054 115.664 139.502 1.00 78.29  ? 23  ASP B C   1 
ATOM 1077 O O   . ASP B 1 23  ? 125.665 114.726 138.983 1.00 83.45  ? 23  ASP B O   1 
ATOM 1078 C CB  . ASP B 1 23  ? 122.748 114.684 139.694 1.00 85.49  ? 23  ASP B CB  1 
ATOM 1079 C CG  . ASP B 1 23  ? 122.623 114.632 141.201 1.00 90.33  ? 23  ASP B CG  1 
ATOM 1080 O OD1 . ASP B 1 23  ? 123.532 115.121 141.902 1.00 86.22  ? 23  ASP B OD1 1 
ATOM 1081 O OD2 . ASP B 1 23  ? 121.609 114.096 141.690 1.00 99.69  ? 23  ASP B OD2 1 
ATOM 1082 N N   . PHE B 1 24  ? 125.620 116.533 140.338 1.00 68.05  ? 24  PHE B N   1 
ATOM 1083 C CA  . PHE B 1 24  ? 127.067 116.564 140.514 1.00 67.43  ? 24  PHE B CA  1 
ATOM 1084 C C   . PHE B 1 24  ? 127.591 115.259 141.099 1.00 70.88  ? 24  PHE B C   1 
ATOM 1085 O O   . PHE B 1 24  ? 128.357 114.538 140.451 1.00 72.65  ? 24  PHE B O   1 
ATOM 1086 C CB  . PHE B 1 24  ? 127.448 117.750 141.391 1.00 67.76  ? 24  PHE B CB  1 
ATOM 1087 C CG  . PHE B 1 24  ? 127.452 119.053 140.661 1.00 67.92  ? 24  PHE B CG  1 
ATOM 1088 C CD1 . PHE B 1 24  ? 127.992 119.142 139.398 1.00 61.79  ? 24  PHE B CD1 1 
ATOM 1089 C CD2 . PHE B 1 24  ? 126.912 120.183 141.231 1.00 64.76  ? 24  PHE B CD2 1 
ATOM 1090 C CE1 . PHE B 1 24  ? 128.002 120.336 138.722 1.00 58.76  ? 24  PHE B CE1 1 
ATOM 1091 C CE2 . PHE B 1 24  ? 126.918 121.379 140.558 1.00 58.03  ? 24  PHE B CE2 1 
ATOM 1092 C CZ  . PHE B 1 24  ? 127.463 121.455 139.303 1.00 56.73  ? 24  PHE B CZ  1 
ATOM 1093 N N   . ARG B 1 25  ? 127.193 114.935 142.328 1.00 73.65  ? 25  ARG B N   1 
ATOM 1094 C CA  . ARG B 1 25  ? 127.728 113.739 142.969 1.00 80.20  ? 25  ARG B CA  1 
ATOM 1095 C C   . ARG B 1 25  ? 127.278 112.471 142.253 1.00 84.68  ? 25  ARG B C   1 
ATOM 1096 O O   . ARG B 1 25  ? 128.068 111.537 142.076 1.00 82.49  ? 25  ARG B O   1 
ATOM 1097 C CB  . ARG B 1 25  ? 127.320 113.697 144.442 1.00 73.06  ? 25  ARG B CB  1 
ATOM 1098 C CG  . ARG B 1 25  ? 127.691 112.399 145.139 1.00 69.79  ? 25  ARG B CG  1 
ATOM 1099 C CD  . ARG B 1 25  ? 127.688 112.542 146.649 1.00 77.40  ? 25  ARG B CD  1 
ATOM 1100 N NE  . ARG B 1 25  ? 128.851 113.273 147.135 1.00 77.05  ? 25  ARG B NE  1 
ATOM 1101 C CZ  . ARG B 1 25  ? 128.851 114.562 147.445 1.00 72.89  ? 25  ARG B CZ  1 
ATOM 1102 N NH1 . ARG B 1 25  ? 127.760 115.300 147.328 1.00 70.77  ? 25  ARG B NH1 1 
ATOM 1103 N NH2 . ARG B 1 25  ? 129.972 115.123 147.886 1.00 68.40  ? 25  ARG B NH2 1 
ATOM 1104 N N   . LYS B 1 26  ? 126.015 112.421 141.828 1.00 81.30  ? 26  LYS B N   1 
ATOM 1105 C CA  . LYS B 1 26  ? 125.481 111.184 141.269 1.00 79.01  ? 26  LYS B CA  1 
ATOM 1106 C C   . LYS B 1 26  ? 126.008 110.922 139.864 1.00 75.18  ? 26  LYS B C   1 
ATOM 1107 O O   . LYS B 1 26  ? 126.276 109.770 139.507 1.00 78.12  ? 26  LYS B O   1 
ATOM 1108 C CB  . LYS B 1 26  ? 123.955 111.223 141.267 1.00 79.67  ? 26  LYS B CB  1 
ATOM 1109 C CG  . LYS B 1 26  ? 123.315 109.925 140.812 1.00 84.87  ? 26  LYS B CG  1 
ATOM 1110 C CD  . LYS B 1 26  ? 121.800 110.002 140.874 1.00 92.37  ? 26  LYS B CD  1 
ATOM 1111 C CE  . LYS B 1 26  ? 121.168 108.664 140.529 1.00 97.65  ? 26  LYS B CE  1 
ATOM 1112 N NZ  . LYS B 1 26  ? 121.585 107.594 141.478 1.00 91.67  ? 26  LYS B NZ  1 
ATOM 1113 N N   . ASP B 1 27  ? 126.165 111.965 139.052 1.00 71.80  ? 27  ASP B N   1 
ATOM 1114 C CA  . ASP B 1 27  ? 126.529 111.790 137.651 1.00 72.26  ? 27  ASP B CA  1 
ATOM 1115 C C   . ASP B 1 27  ? 127.955 112.210 137.337 1.00 74.84  ? 27  ASP B C   1 
ATOM 1116 O O   . ASP B 1 27  ? 128.747 111.384 136.885 1.00 80.43  ? 27  ASP B O   1 
ATOM 1117 C CB  . ASP B 1 27  ? 125.553 112.556 136.748 1.00 71.08  ? 27  ASP B CB  1 
ATOM 1118 C CG  . ASP B 1 27  ? 124.169 111.938 136.733 1.00 82.77  ? 27  ASP B CG  1 
ATOM 1119 O OD1 . ASP B 1 27  ? 123.338 112.305 137.588 1.00 84.61  ? 27  ASP B OD1 1 
ATOM 1120 O OD2 . ASP B 1 27  ? 123.912 111.076 135.870 1.00 88.91  ? 27  ASP B OD2 1 
ATOM 1121 N N   . LEU B 1 28  ? 128.322 113.468 137.572 1.00 69.45  ? 28  LEU B N   1 
ATOM 1122 C CA  . LEU B 1 28  ? 129.665 113.905 137.213 1.00 65.82  ? 28  LEU B CA  1 
ATOM 1123 C C   . LEU B 1 28  ? 130.743 113.333 138.121 1.00 69.56  ? 28  LEU B C   1 
ATOM 1124 O O   . LEU B 1 28  ? 131.924 113.408 137.772 1.00 73.88  ? 28  LEU B O   1 
ATOM 1125 C CB  . LEU B 1 28  ? 129.760 115.427 137.233 1.00 63.81  ? 28  LEU B CB  1 
ATOM 1126 C CG  . LEU B 1 28  ? 128.813 116.177 136.308 1.00 62.66  ? 28  LEU B CG  1 
ATOM 1127 C CD1 . LEU B 1 28  ? 129.167 117.645 136.299 1.00 68.23  ? 28  LEU B CD1 1 
ATOM 1128 C CD2 . LEU B 1 28  ? 128.868 115.606 134.920 1.00 66.23  ? 28  LEU B CD2 1 
ATOM 1129 N N   . GLY B 1 29  ? 130.376 112.775 139.269 1.00 71.61  ? 29  GLY B N   1 
ATOM 1130 C CA  . GLY B 1 29  ? 131.378 112.268 140.179 1.00 72.90  ? 29  GLY B CA  1 
ATOM 1131 C C   . GLY B 1 29  ? 132.152 113.331 140.917 1.00 73.46  ? 29  GLY B C   1 
ATOM 1132 O O   . GLY B 1 29  ? 133.151 113.011 141.566 1.00 75.04  ? 29  GLY B O   1 
ATOM 1133 N N   . TRP B 1 30  ? 131.725 114.588 140.838 1.00 71.53  ? 30  TRP B N   1 
ATOM 1134 C CA  . TRP B 1 30  ? 132.380 115.685 141.543 1.00 65.94  ? 30  TRP B CA  1 
ATOM 1135 C C   . TRP B 1 30  ? 131.819 115.729 142.954 1.00 64.72  ? 30  TRP B C   1 
ATOM 1136 O O   . TRP B 1 30  ? 130.713 116.222 143.179 1.00 70.57  ? 30  TRP B O   1 
ATOM 1137 C CB  . TRP B 1 30  ? 132.158 117.006 140.821 1.00 63.91  ? 30  TRP B CB  1 
ATOM 1138 C CG  . TRP B 1 30  ? 132.767 117.063 139.474 1.00 65.71  ? 30  TRP B CG  1 
ATOM 1139 C CD1 . TRP B 1 30  ? 133.571 116.130 138.898 1.00 64.57  ? 30  TRP B CD1 1 
ATOM 1140 C CD2 . TRP B 1 30  ? 132.623 118.113 138.521 1.00 62.19  ? 30  TRP B CD2 1 
ATOM 1141 N NE1 . TRP B 1 30  ? 133.940 116.534 137.642 1.00 59.00  ? 30  TRP B NE1 1 
ATOM 1142 C CE2 . TRP B 1 30  ? 133.370 117.752 137.387 1.00 59.92  ? 30  TRP B CE2 1 
ATOM 1143 C CE3 . TRP B 1 30  ? 131.938 119.326 138.517 1.00 56.16  ? 30  TRP B CE3 1 
ATOM 1144 C CZ2 . TRP B 1 30  ? 133.446 118.558 136.262 1.00 60.92  ? 30  TRP B CZ2 1 
ATOM 1145 C CZ3 . TRP B 1 30  ? 132.017 120.122 137.405 1.00 55.88  ? 30  TRP B CZ3 1 
ATOM 1146 C CH2 . TRP B 1 30  ? 132.765 119.739 136.291 1.00 60.13  ? 30  TRP B CH2 1 
ATOM 1147 N N   . LYS B 1 31  ? 132.579 115.210 143.909 1.00 61.25  ? 31  LYS B N   1 
ATOM 1148 C CA  . LYS B 1 31  ? 132.151 115.177 145.296 1.00 64.01  ? 31  LYS B CA  1 
ATOM 1149 C C   . LYS B 1 31  ? 132.515 116.446 146.046 1.00 59.88  ? 31  LYS B C   1 
ATOM 1150 O O   . LYS B 1 31  ? 132.126 116.601 147.205 1.00 64.18  ? 31  LYS B O   1 
ATOM 1151 C CB  . LYS B 1 31  ? 132.752 113.958 145.996 1.00 68.71  ? 31  LYS B CB  1 
ATOM 1152 C CG  . LYS B 1 31  ? 132.252 112.633 145.452 1.00 69.17  ? 31  LYS B CG  1 
ATOM 1153 C CD  . LYS B 1 31  ? 133.133 111.485 145.897 1.00 67.83  ? 31  LYS B CD  1 
ATOM 1154 C CE  . LYS B 1 31  ? 134.533 111.626 145.334 1.00 62.72  ? 31  LYS B CE  1 
ATOM 1155 N NZ  . LYS B 1 31  ? 135.399 110.476 145.709 1.00 70.06  ? 31  LYS B NZ  1 
ATOM 1156 N N   . TRP B 1 32  ? 133.236 117.363 145.410 1.00 56.06  ? 32  TRP B N   1 
ATOM 1157 C CA  . TRP B 1 32  ? 133.754 118.535 146.095 1.00 54.86  ? 32  TRP B CA  1 
ATOM 1158 C C   . TRP B 1 32  ? 132.782 119.700 146.119 1.00 55.60  ? 32  TRP B C   1 
ATOM 1159 O O   . TRP B 1 32  ? 133.124 120.754 146.660 1.00 61.43  ? 32  TRP B O   1 
ATOM 1160 C CB  . TRP B 1 32  ? 135.064 118.992 145.450 1.00 51.86  ? 32  TRP B CB  1 
ATOM 1161 C CG  . TRP B 1 32  ? 134.918 119.474 144.049 1.00 54.59  ? 32  TRP B CG  1 
ATOM 1162 C CD1 . TRP B 1 32  ? 134.827 118.709 142.931 1.00 59.17  ? 32  TRP B CD1 1 
ATOM 1163 C CD2 . TRP B 1 32  ? 134.866 120.834 143.610 1.00 54.66  ? 32  TRP B CD2 1 
ATOM 1164 N NE1 . TRP B 1 32  ? 134.712 119.506 141.821 1.00 61.64  ? 32  TRP B NE1 1 
ATOM 1165 C CE2 . TRP B 1 32  ? 134.734 120.816 142.213 1.00 57.92  ? 32  TRP B CE2 1 
ATOM 1166 C CE3 . TRP B 1 32  ? 134.915 122.065 144.264 1.00 57.05  ? 32  TRP B CE3 1 
ATOM 1167 C CZ2 . TRP B 1 32  ? 134.649 121.978 141.459 1.00 58.47  ? 32  TRP B CZ2 1 
ATOM 1168 C CZ3 . TRP B 1 32  ? 134.829 123.216 143.512 1.00 57.07  ? 32  TRP B CZ3 1 
ATOM 1169 C CH2 . TRP B 1 32  ? 134.699 123.165 142.126 1.00 50.51  ? 32  TRP B CH2 1 
ATOM 1170 N N   . ILE B 1 33  ? 131.595 119.547 145.556 1.00 53.34  ? 33  ILE B N   1 
ATOM 1171 C CA  . ILE B 1 33  ? 130.642 120.645 145.462 1.00 53.34  ? 33  ILE B CA  1 
ATOM 1172 C C   . ILE B 1 33  ? 129.621 120.520 146.582 1.00 59.82  ? 33  ILE B C   1 
ATOM 1173 O O   . ILE B 1 33  ? 128.983 119.474 146.742 1.00 63.91  ? 33  ILE B O   1 
ATOM 1174 C CB  . ILE B 1 33  ? 129.961 120.659 144.087 1.00 50.70  ? 33  ILE B CB  1 
ATOM 1175 C CG1 . ILE B 1 33  ? 130.854 121.366 143.076 1.00 53.13  ? 33  ILE B CG1 1 
ATOM 1176 C CG2 . ILE B 1 33  ? 128.626 121.344 144.163 1.00 53.75  ? 33  ILE B CG2 1 
ATOM 1177 C CD1 . ILE B 1 33  ? 130.249 121.469 141.716 1.00 58.34  ? 33  ILE B CD1 1 
ATOM 1178 N N   . HIS B 1 34  ? 129.469 121.590 147.361 1.00 64.29  ? 34  HIS B N   1 
ATOM 1179 C CA  . HIS B 1 34  ? 128.500 121.624 148.447 1.00 61.37  ? 34  HIS B CA  1 
ATOM 1180 C C   . HIS B 1 34  ? 127.139 122.145 148.017 1.00 58.22  ? 34  HIS B C   1 
ATOM 1181 O O   . HIS B 1 34  ? 126.120 121.668 148.524 1.00 59.16  ? 34  HIS B O   1 
ATOM 1182 C CB  . HIS B 1 34  ? 129.021 122.485 149.601 1.00 57.73  ? 34  HIS B CB  1 
ATOM 1183 C CG  . HIS B 1 34  ? 128.083 122.562 150.763 1.00 59.55  ? 34  HIS B CG  1 
ATOM 1184 N ND1 . HIS B 1 34  ? 127.595 123.755 151.247 1.00 60.53  ? 34  HIS B ND1 1 
ATOM 1185 C CD2 . HIS B 1 34  ? 127.533 121.592 151.529 1.00 63.61  ? 34  HIS B CD2 1 
ATOM 1186 C CE1 . HIS B 1 34  ? 126.789 123.517 152.266 1.00 61.83  ? 34  HIS B CE1 1 
ATOM 1187 N NE2 . HIS B 1 34  ? 126.734 122.212 152.457 1.00 61.36  ? 34  HIS B NE2 1 
ATOM 1188 N N   . GLU B 1 35  ? 127.096 123.104 147.091 1.00 56.38  ? 35  GLU B N   1 
ATOM 1189 C CA  . GLU B 1 35  ? 125.828 123.635 146.623 1.00 58.05  ? 35  GLU B CA  1 
ATOM 1190 C C   . GLU B 1 35  ? 126.067 124.339 145.302 1.00 59.69  ? 35  GLU B C   1 
ATOM 1191 O O   . GLU B 1 35  ? 127.051 125.080 145.189 1.00 59.51  ? 35  GLU B O   1 
ATOM 1192 C CB  . GLU B 1 35  ? 125.227 124.605 147.645 1.00 65.21  ? 35  GLU B CB  1 
ATOM 1193 C CG  . GLU B 1 35  ? 123.735 124.817 147.494 1.00 82.54  ? 35  GLU B CG  1 
ATOM 1194 C CD  . GLU B 1 35  ? 123.173 125.775 148.518 1.00 99.99  ? 35  GLU B CD  1 
ATOM 1195 O OE1 . GLU B 1 35  ? 123.928 126.190 149.422 1.00 105.20 ? 35  GLU B OE1 1 
ATOM 1196 O OE2 . GLU B 1 35  ? 121.976 126.114 148.417 1.00 103.26 ? 35  GLU B OE2 1 
ATOM 1197 N N   . PRO B 1 36  ? 125.207 124.152 144.293 1.00 59.35  ? 36  PRO B N   1 
ATOM 1198 C CA  . PRO B 1 36  ? 123.985 123.340 144.268 1.00 61.41  ? 36  PRO B CA  1 
ATOM 1199 C C   . PRO B 1 36  ? 124.292 121.862 144.151 1.00 66.91  ? 36  PRO B C   1 
ATOM 1200 O O   . PRO B 1 36  ? 125.298 121.491 143.564 1.00 70.01  ? 36  PRO B O   1 
ATOM 1201 C CB  . PRO B 1 36  ? 123.244 123.853 143.020 1.00 60.55  ? 36  PRO B CB  1 
ATOM 1202 C CG  . PRO B 1 36  ? 123.999 125.074 142.552 1.00 60.30  ? 36  PRO B CG  1 
ATOM 1203 C CD  . PRO B 1 36  ? 125.396 124.856 143.020 1.00 58.29  ? 36  PRO B CD  1 
ATOM 1204 N N   . LYS B 1 37  ? 123.442 120.988 144.684 1.00 65.72  ? 37  LYS B N   1 
ATOM 1205 C CA  . LYS B 1 37  ? 123.693 119.558 144.584 1.00 72.65  ? 37  LYS B CA  1 
ATOM 1206 C C   . LYS B 1 37  ? 123.460 119.016 143.182 1.00 73.90  ? 37  LYS B C   1 
ATOM 1207 O O   . LYS B 1 37  ? 123.759 117.845 142.932 1.00 78.03  ? 37  LYS B O   1 
ATOM 1208 C CB  . LYS B 1 37  ? 122.828 118.797 145.589 1.00 75.73  ? 37  LYS B CB  1 
ATOM 1209 C CG  . LYS B 1 37  ? 121.355 119.145 145.539 1.00 81.51  ? 37  LYS B CG  1 
ATOM 1210 C CD  . LYS B 1 37  ? 120.589 118.426 146.641 1.00 86.43  ? 37  LYS B CD  1 
ATOM 1211 C CE  . LYS B 1 37  ? 120.690 116.919 146.494 1.00 85.78  ? 37  LYS B CE  1 
ATOM 1212 N NZ  . LYS B 1 37  ? 120.106 116.456 145.206 1.00 77.03  ? 37  LYS B NZ  1 
ATOM 1213 N N   . GLY B 1 38  ? 122.930 119.832 142.276 1.00 72.60  ? 38  GLY B N   1 
ATOM 1214 C CA  . GLY B 1 38  ? 122.733 119.455 140.891 1.00 71.40  ? 38  GLY B CA  1 
ATOM 1215 C C   . GLY B 1 38  ? 122.058 120.575 140.130 1.00 67.95  ? 38  GLY B C   1 
ATOM 1216 O O   . GLY B 1 38  ? 121.127 121.192 140.651 1.00 72.58  ? 38  GLY B O   1 
ATOM 1217 N N   . TYR B 1 39  ? 122.495 120.852 138.907 1.00 60.42  ? 39  TYR B N   1 
ATOM 1218 C CA  . TYR B 1 39  ? 122.001 122.026 138.203 1.00 55.07  ? 39  TYR B CA  1 
ATOM 1219 C C   . TYR B 1 39  ? 121.369 121.621 136.878 1.00 65.65  ? 39  TYR B C   1 
ATOM 1220 O O   . TYR B 1 39  ? 121.295 120.440 136.528 1.00 71.68  ? 39  TYR B O   1 
ATOM 1221 C CB  . TYR B 1 39  ? 123.111 123.062 137.992 1.00 55.25  ? 39  TYR B CB  1 
ATOM 1222 C CG  . TYR B 1 39  ? 124.063 122.778 136.853 1.00 60.37  ? 39  TYR B CG  1 
ATOM 1223 C CD1 . TYR B 1 39  ? 124.655 121.536 136.698 1.00 63.96  ? 39  TYR B CD1 1 
ATOM 1224 C CD2 . TYR B 1 39  ? 124.376 123.765 135.936 1.00 53.98  ? 39  TYR B CD2 1 
ATOM 1225 C CE1 . TYR B 1 39  ? 125.528 121.292 135.661 1.00 52.70  ? 39  TYR B CE1 1 
ATOM 1226 C CE2 . TYR B 1 39  ? 125.243 123.526 134.904 1.00 48.34  ? 39  TYR B CE2 1 
ATOM 1227 C CZ  . TYR B 1 39  ? 125.814 122.293 134.769 1.00 48.27  ? 39  TYR B CZ  1 
ATOM 1228 O OH  . TYR B 1 39  ? 126.677 122.068 133.730 1.00 53.16  ? 39  TYR B OH  1 
ATOM 1229 N N   . HIS B 1 40  ? 120.889 122.625 136.147 1.00 69.58  ? 40  HIS B N   1 
ATOM 1230 C CA  . HIS B 1 40  ? 120.176 122.429 134.887 1.00 73.21  ? 40  HIS B CA  1 
ATOM 1231 C C   . HIS B 1 40  ? 121.117 122.758 133.737 1.00 74.41  ? 40  HIS B C   1 
ATOM 1232 O O   . HIS B 1 40  ? 121.340 123.928 133.417 1.00 73.78  ? 40  HIS B O   1 
ATOM 1233 C CB  . HIS B 1 40  ? 118.921 123.293 134.834 1.00 69.18  ? 40  HIS B CB  1 
ATOM 1234 C CG  . HIS B 1 40  ? 117.703 122.626 135.391 1.00 73.86  ? 40  HIS B CG  1 
ATOM 1235 N ND1 . HIS B 1 40  ? 117.693 121.998 136.617 1.00 76.86  ? 40  HIS B ND1 1 
ATOM 1236 C CD2 . HIS B 1 40  ? 116.454 122.492 134.888 1.00 77.61  ? 40  HIS B CD2 1 
ATOM 1237 C CE1 . HIS B 1 40  ? 116.489 121.507 136.846 1.00 78.48  ? 40  HIS B CE1 1 
ATOM 1238 N NE2 . HIS B 1 40  ? 115.719 121.792 135.812 1.00 85.16  ? 40  HIS B NE2 1 
ATOM 1239 N N   . ALA B 1 41  ? 121.661 121.721 133.111 1.00 70.54  ? 41  ALA B N   1 
ATOM 1240 C CA  . ALA B 1 41  ? 122.523 121.858 131.944 1.00 65.46  ? 41  ALA B CA  1 
ATOM 1241 C C   . ALA B 1 41  ? 121.734 121.372 130.735 1.00 71.87  ? 41  ALA B C   1 
ATOM 1242 O O   . ALA B 1 41  ? 121.763 120.196 130.377 1.00 80.45  ? 41  ALA B O   1 
ATOM 1243 C CB  . ALA B 1 41  ? 123.812 121.080 132.124 1.00 66.42  ? 41  ALA B CB  1 
ATOM 1244 N N   . ASN B 1 42  ? 121.017 122.296 130.109 1.00 62.55  ? 42  ASN B N   1 
ATOM 1245 C CA  . ASN B 1 42  ? 120.266 121.974 128.907 1.00 69.62  ? 42  ASN B CA  1 
ATOM 1246 C C   . ASN B 1 42  ? 121.205 121.454 127.829 1.00 78.03  ? 42  ASN B C   1 
ATOM 1247 O O   . ASN B 1 42  ? 122.336 121.923 127.698 1.00 84.73  ? 42  ASN B O   1 
ATOM 1248 C CB  . ASN B 1 42  ? 119.536 123.219 128.414 1.00 77.09  ? 42  ASN B CB  1 
ATOM 1249 C CG  . ASN B 1 42  ? 118.809 123.937 129.520 1.00 79.84  ? 42  ASN B CG  1 
ATOM 1250 O OD1 . ASN B 1 42  ? 118.175 123.310 130.365 1.00 82.41  ? 42  ASN B OD1 1 
ATOM 1251 N ND2 . ASN B 1 42  ? 118.901 125.259 129.530 1.00 80.15  ? 42  ASN B ND2 1 
ATOM 1252 N N   . PHE B 1 43  ? 120.745 120.473 127.060 1.00 79.99  ? 43  PHE B N   1 
ATOM 1253 C CA  . PHE B 1 43  ? 121.567 119.899 126.006 1.00 79.25  ? 43  PHE B CA  1 
ATOM 1254 C C   . PHE B 1 43  ? 120.901 120.091 124.653 1.00 80.97  ? 43  PHE B C   1 
ATOM 1255 O O   . PHE B 1 43  ? 119.680 119.972 124.530 1.00 88.57  ? 43  PHE B O   1 
ATOM 1256 C CB  . PHE B 1 43  ? 121.845 118.417 126.261 1.00 78.30  ? 43  PHE B CB  1 
ATOM 1257 C CG  . PHE B 1 43  ? 120.662 117.527 126.056 1.00 76.75  ? 43  PHE B CG  1 
ATOM 1258 C CD1 . PHE B 1 43  ? 119.648 117.473 126.987 1.00 82.16  ? 43  PHE B CD1 1 
ATOM 1259 C CD2 . PHE B 1 43  ? 120.580 116.717 124.945 1.00 78.81  ? 43  PHE B CD2 1 
ATOM 1260 C CE1 . PHE B 1 43  ? 118.566 116.643 126.804 1.00 80.94  ? 43  PHE B CE1 1 
ATOM 1261 C CE2 . PHE B 1 43  ? 119.501 115.888 124.757 1.00 84.40  ? 43  PHE B CE2 1 
ATOM 1262 C CZ  . PHE B 1 43  ? 118.494 115.851 125.688 1.00 80.76  ? 43  PHE B CZ  1 
ATOM 1263 N N   . CYS B 1 44  ? 121.708 120.412 123.648 1.00 76.15  ? 44  CYS B N   1 
ATOM 1264 C CA  . CYS B 1 44  ? 121.205 120.660 122.304 1.00 82.65  ? 44  CYS B CA  1 
ATOM 1265 C C   . CYS B 1 44  ? 120.980 119.337 121.588 1.00 90.22  ? 44  CYS B C   1 
ATOM 1266 O O   . CYS B 1 44  ? 121.863 118.474 121.583 1.00 91.69  ? 44  CYS B O   1 
ATOM 1267 C CB  . CYS B 1 44  ? 122.189 121.524 121.526 1.00 79.22  ? 44  CYS B CB  1 
ATOM 1268 S SG  . CYS B 1 44  ? 122.454 123.137 122.242 1.00 97.76  ? 44  CYS B SG  1 
ATOM 1269 N N   . LEU B 1 45  ? 119.809 119.178 120.975 1.00 92.13  ? 45  LEU B N   1 
ATOM 1270 C CA  . LEU B 1 45  ? 119.498 117.945 120.268 1.00 88.62  ? 45  LEU B CA  1 
ATOM 1271 C C   . LEU B 1 45  ? 118.459 118.233 119.198 1.00 97.93  ? 45  LEU B C   1 
ATOM 1272 O O   . LEU B 1 45  ? 117.579 119.074 119.392 1.00 103.95 ? 45  LEU B O   1 
ATOM 1273 C CB  . LEU B 1 45  ? 118.984 116.871 121.230 1.00 86.01  ? 45  LEU B CB  1 
ATOM 1274 C CG  . LEU B 1 45  ? 118.665 115.519 120.602 1.00 93.68  ? 45  LEU B CG  1 
ATOM 1275 C CD1 . LEU B 1 45  ? 119.881 114.990 119.867 1.00 92.14  ? 45  LEU B CD1 1 
ATOM 1276 C CD2 . LEU B 1 45  ? 118.202 114.535 121.660 1.00 96.36  ? 45  LEU B CD2 1 
ATOM 1277 N N   . GLY B 1 46  ? 118.568 117.536 118.069 1.00 97.12  ? 46  GLY B N   1 
ATOM 1278 C CA  . GLY B 1 46  ? 117.593 117.656 117.012 1.00 100.97 ? 46  GLY B CA  1 
ATOM 1279 C C   . GLY B 1 46  ? 118.213 117.795 115.638 1.00 104.19 ? 46  GLY B C   1 
ATOM 1280 O O   . GLY B 1 46  ? 119.256 118.430 115.461 1.00 108.67 ? 46  GLY B O   1 
ATOM 1281 N N   . PRO B 1 47  ? 117.576 117.198 114.634 1.00 106.40 ? 47  PRO B N   1 
ATOM 1282 C CA  . PRO B 1 47  ? 118.084 117.316 113.264 1.00 109.20 ? 47  PRO B CA  1 
ATOM 1283 C C   . PRO B 1 47  ? 117.993 118.746 112.756 1.00 105.72 ? 47  PRO B C   1 
ATOM 1284 O O   . PRO B 1 47  ? 117.190 119.550 113.232 1.00 104.90 ? 47  PRO B O   1 
ATOM 1285 C CB  . PRO B 1 47  ? 117.172 116.378 112.465 1.00 107.92 ? 47  PRO B CB  1 
ATOM 1286 C CG  . PRO B 1 47  ? 115.934 116.262 113.288 1.00 106.23 ? 47  PRO B CG  1 
ATOM 1287 C CD  . PRO B 1 47  ? 116.389 116.331 114.712 1.00 103.10 ? 47  PRO B CD  1 
ATOM 1288 N N   . CYS B 1 48  ? 118.841 119.059 111.775 1.00 104.13 ? 48  CYS B N   1 
ATOM 1289 C CA  . CYS B 1 48  ? 118.935 120.396 111.197 1.00 105.35 ? 48  CYS B CA  1 
ATOM 1290 C C   . CYS B 1 48  ? 118.579 120.350 109.716 1.00 110.86 ? 48  CYS B C   1 
ATOM 1291 O O   . CYS B 1 48  ? 119.450 120.098 108.871 1.00 113.34 ? 48  CYS B O   1 
ATOM 1292 C CB  . CYS B 1 48  ? 120.342 120.962 111.392 1.00 98.83  ? 48  CYS B CB  1 
ATOM 1293 S SG  . CYS B 1 48  ? 120.797 121.287 113.096 1.00 97.72  ? 48  CYS B SG  1 
ATOM 1294 N N   . PRO B 1 49  ? 117.328 120.582 109.347 1.00 110.56 ? 49  PRO B N   1 
ATOM 1295 C CA  . PRO B 1 49  ? 116.970 120.719 107.933 1.00 105.27 ? 49  PRO B CA  1 
ATOM 1296 C C   . PRO B 1 49  ? 117.504 122.034 107.375 1.00 106.50 ? 49  PRO B C   1 
ATOM 1297 O O   . PRO B 1 49  ? 117.906 122.932 108.110 1.00 105.43 ? 49  PRO B O   1 
ATOM 1298 C CB  . PRO B 1 49  ? 115.440 120.694 107.951 1.00 108.03 ? 49  PRO B CB  1 
ATOM 1299 C CG  . PRO B 1 49  ? 115.080 120.044 109.243 1.00 109.21 ? 49  PRO B CG  1 
ATOM 1300 C CD  . PRO B 1 49  ? 116.138 120.480 110.205 1.00 113.55 ? 49  PRO B CD  1 
ATOM 1301 N N   . TYR B 1 50  ? 117.493 122.131 106.044 1.00 109.00 ? 50  TYR B N   1 
ATOM 1302 C CA  . TYR B 1 50  ? 118.044 123.309 105.381 1.00 108.64 ? 50  TYR B CA  1 
ATOM 1303 C C   . TYR B 1 50  ? 117.289 124.570 105.775 1.00 110.78 ? 50  TYR B C   1 
ATOM 1304 O O   . TYR B 1 50  ? 117.879 125.650 105.886 1.00 112.55 ? 50  TYR B O   1 
ATOM 1305 C CB  . TYR B 1 50  ? 118.020 123.123 103.866 1.00 105.44 ? 50  TYR B CB  1 
ATOM 1306 C CG  . TYR B 1 50  ? 118.552 124.317 103.108 1.00 106.01 ? 50  TYR B CG  1 
ATOM 1307 C CD1 . TYR B 1 50  ? 119.787 124.863 103.419 1.00 104.30 ? 50  TYR B CD1 1 
ATOM 1308 C CD2 . TYR B 1 50  ? 117.823 124.893 102.078 1.00 106.49 ? 50  TYR B CD2 1 
ATOM 1309 C CE1 . TYR B 1 50  ? 120.280 125.952 102.732 1.00 104.78 ? 50  TYR B CE1 1 
ATOM 1310 C CE2 . TYR B 1 50  ? 118.310 125.984 101.383 1.00 110.59 ? 50  TYR B CE2 1 
ATOM 1311 C CZ  . TYR B 1 50  ? 119.540 126.508 101.716 1.00 110.51 ? 50  TYR B CZ  1 
ATOM 1312 O OH  . TYR B 1 50  ? 120.033 127.593 101.030 1.00 110.67 ? 50  TYR B OH  1 
ATOM 1313 N N   . ILE B 1 51  ? 115.980 124.458 105.980 1.00 112.36 ? 51  ILE B N   1 
ATOM 1314 C CA  . ILE B 1 51  ? 115.193 125.597 106.435 1.00 115.81 ? 51  ILE B CA  1 
ATOM 1315 C C   . ILE B 1 51  ? 115.214 125.612 107.957 1.00 114.45 ? 51  ILE B C   1 
ATOM 1316 O O   . ILE B 1 51  ? 114.272 125.146 108.608 1.00 116.30 ? 51  ILE B O   1 
ATOM 1317 C CB  . ILE B 1 51  ? 113.753 125.539 105.895 1.00 113.32 ? 51  ILE B CB  1 
ATOM 1318 C CG1 . ILE B 1 51  ? 113.762 125.264 104.392 1.00 110.40 ? 51  ILE B CG1 1 
ATOM 1319 C CG2 . ILE B 1 51  ? 113.025 126.842 106.182 1.00 104.47 ? 51  ILE B CG2 1 
ATOM 1320 C CD1 . ILE B 1 51  ? 114.477 126.324 103.582 1.00 110.97 ? 51  ILE B CD1 1 
ATOM 1321 N N   . TRP B 1 52  ? 116.287 126.152 108.531 1.00 115.46 ? 52  TRP B N   1 
ATOM 1322 C CA  . TRP B 1 52  ? 116.436 126.208 109.979 1.00 119.29 ? 52  TRP B CA  1 
ATOM 1323 C C   . TRP B 1 52  ? 117.551 127.178 110.348 1.00 116.51 ? 52  TRP B C   1 
ATOM 1324 O O   . TRP B 1 52  ? 118.078 127.883 109.482 1.00 112.66 ? 52  TRP B O   1 
ATOM 1325 C CB  . TRP B 1 52  ? 116.711 124.812 110.545 1.00 116.41 ? 52  TRP B CB  1 
ATOM 1326 C CG  . TRP B 1 52  ? 116.291 124.629 111.977 1.00 115.91 ? 52  TRP B CG  1 
ATOM 1327 C CD1 . TRP B 1 52  ? 117.080 124.235 113.014 1.00 114.67 ? 52  TRP B CD1 1 
ATOM 1328 C CD2 . TRP B 1 52  ? 114.983 124.836 112.526 1.00 117.08 ? 52  TRP B CD2 1 
ATOM 1329 N NE1 . TRP B 1 52  ? 116.347 124.179 114.173 1.00 113.49 ? 52  TRP B NE1 1 
ATOM 1330 C CE2 . TRP B 1 52  ? 115.057 124.545 113.901 1.00 114.99 ? 52  TRP B CE2 1 
ATOM 1331 C CE3 . TRP B 1 52  ? 113.758 125.239 111.989 1.00 119.25 ? 52  TRP B CE3 1 
ATOM 1332 C CZ2 . TRP B 1 52  ? 113.958 124.646 114.744 1.00 117.03 ? 52  TRP B CZ2 1 
ATOM 1333 C CZ3 . TRP B 1 52  ? 112.667 125.337 112.829 1.00 120.11 ? 52  TRP B CZ3 1 
ATOM 1334 C CH2 . TRP B 1 52  ? 112.774 125.041 114.191 1.00 120.82 ? 52  TRP B CH2 1 
ATOM 1335 N N   . SER B 1 53  ? 117.920 127.223 111.628 1.00 118.65 ? 53  SER B N   1 
ATOM 1336 C CA  . SER B 1 53  ? 118.926 128.170 112.109 1.00 122.77 ? 53  SER B CA  1 
ATOM 1337 C C   . SER B 1 53  ? 120.307 127.694 111.666 1.00 123.59 ? 53  SER B C   1 
ATOM 1338 O O   . SER B 1 53  ? 121.068 127.080 112.418 1.00 122.36 ? 53  SER B O   1 
ATOM 1339 C CB  . SER B 1 53  ? 118.845 128.320 113.623 1.00 117.23 ? 53  SER B CB  1 
ATOM 1340 O OG  . SER B 1 53  ? 119.843 129.208 114.099 1.00 105.34 ? 53  SER B OG  1 
ATOM 1341 N N   . LEU B 1 54  ? 120.630 127.990 110.412 1.00 119.18 ? 54  LEU B N   1 
ATOM 1342 C CA  . LEU B 1 54  ? 121.948 127.702 109.869 1.00 115.89 ? 54  LEU B CA  1 
ATOM 1343 C C   . LEU B 1 54  ? 122.824 128.941 109.978 1.00 117.23 ? 54  LEU B C   1 
ATOM 1344 O O   . LEU B 1 54  ? 122.453 130.022 109.514 1.00 121.76 ? 54  LEU B O   1 
ATOM 1345 C CB  . LEU B 1 54  ? 121.843 127.249 108.414 1.00 108.80 ? 54  LEU B CB  1 
ATOM 1346 C CG  . LEU B 1 54  ? 120.998 125.996 108.189 1.00 102.55 ? 54  LEU B CG  1 
ATOM 1347 C CD1 . LEU B 1 54  ? 121.012 125.607 106.728 1.00 103.60 ? 54  LEU B CD1 1 
ATOM 1348 C CD2 . LEU B 1 54  ? 121.493 124.853 109.049 1.00 97.29  ? 54  LEU B CD2 1 
ATOM 1349 N N   . ASP B 1 55  ? 123.993 128.776 110.595 1.00 114.92 ? 55  ASP B N   1 
ATOM 1350 C CA  . ASP B 1 55  ? 124.834 129.916 110.946 1.00 119.98 ? 55  ASP B CA  1 
ATOM 1351 C C   . ASP B 1 55  ? 125.920 130.185 109.906 1.00 116.50 ? 55  ASP B C   1 
ATOM 1352 O O   . ASP B 1 55  ? 126.022 131.298 109.382 1.00 115.59 ? 55  ASP B O   1 
ATOM 1353 C CB  . ASP B 1 55  ? 125.452 129.691 112.331 1.00 119.52 ? 55  ASP B CB  1 
ATOM 1354 C CG  . ASP B 1 55  ? 126.101 128.328 112.466 1.00 118.61 ? 55  ASP B CG  1 
ATOM 1355 O OD1 . ASP B 1 55  ? 126.118 127.577 111.469 1.00 123.07 ? 55  ASP B OD1 1 
ATOM 1356 O OD2 . ASP B 1 55  ? 126.596 128.011 113.568 1.00 109.31 ? 55  ASP B OD2 1 
ATOM 1357 N N   . THR B 1 56  ? 126.735 129.181 109.600 1.00 110.54 ? 56  THR B N   1 
ATOM 1358 C CA  . THR B 1 56  ? 127.885 129.355 108.729 1.00 102.39 ? 56  THR B CA  1 
ATOM 1359 C C   . THR B 1 56  ? 127.551 128.907 107.311 1.00 103.81 ? 56  THR B C   1 
ATOM 1360 O O   . THR B 1 56  ? 126.604 128.156 107.072 1.00 104.13 ? 56  THR B O   1 
ATOM 1361 C CB  . THR B 1 56  ? 129.090 128.586 109.274 1.00 100.35 ? 56  THR B CB  1 
ATOM 1362 O OG1 . THR B 1 56  ? 128.708 127.237 109.565 1.00 98.31  ? 56  THR B OG1 1 
ATOM 1363 C CG2 . THR B 1 56  ? 129.613 129.243 110.539 1.00 105.07 ? 56  THR B CG2 1 
ATOM 1364 N N   . GLN B 1 57  ? 128.348 129.387 106.354 1.00 106.60 ? 57  GLN B N   1 
ATOM 1365 C CA  . GLN B 1 57  ? 128.150 128.993 104.963 1.00 106.75 ? 57  GLN B CA  1 
ATOM 1366 C C   . GLN B 1 57  ? 128.395 127.503 104.775 1.00 95.59  ? 57  GLN B C   1 
ATOM 1367 O O   . GLN B 1 57  ? 127.673 126.838 104.023 1.00 93.91  ? 57  GLN B O   1 
ATOM 1368 C CB  . GLN B 1 57  ? 129.065 129.809 104.052 1.00 111.45 ? 57  GLN B CB  1 
ATOM 1369 C CG  . GLN B 1 57  ? 128.343 130.534 102.934 1.00 113.83 ? 57  GLN B CG  1 
ATOM 1370 C CD  . GLN B 1 57  ? 127.751 129.583 101.919 1.00 114.06 ? 57  GLN B CD  1 
ATOM 1371 O OE1 . GLN B 1 57  ? 128.218 128.457 101.767 1.00 115.24 ? 57  GLN B OE1 1 
ATOM 1372 N NE2 . GLN B 1 57  ? 126.716 130.031 101.218 1.00 111.97 ? 57  GLN B NE2 1 
ATOM 1373 N N   . TYR B 1 58  ? 129.408 126.960 105.452 1.00 90.94  ? 58  TYR B N   1 
ATOM 1374 C CA  . TYR B 1 58  ? 129.633 125.523 105.389 1.00 88.34  ? 58  TYR B CA  1 
ATOM 1375 C C   . TYR B 1 58  ? 128.451 124.761 105.967 1.00 91.12  ? 58  TYR B C   1 
ATOM 1376 O O   . TYR B 1 58  ? 128.148 123.647 105.528 1.00 93.11  ? 58  TYR B O   1 
ATOM 1377 C CB  . TYR B 1 58  ? 130.913 125.145 106.127 1.00 86.78  ? 58  TYR B CB  1 
ATOM 1378 C CG  . TYR B 1 58  ? 131.062 123.656 106.302 1.00 81.47  ? 58  TYR B CG  1 
ATOM 1379 C CD1 . TYR B 1 58  ? 131.573 122.870 105.286 1.00 82.62  ? 58  TYR B CD1 1 
ATOM 1380 C CD2 . TYR B 1 58  ? 130.678 123.036 107.479 1.00 80.72  ? 58  TYR B CD2 1 
ATOM 1381 C CE1 . TYR B 1 58  ? 131.703 121.512 105.440 1.00 83.26  ? 58  TYR B CE1 1 
ATOM 1382 C CE2 . TYR B 1 58  ? 130.800 121.681 107.637 1.00 80.33  ? 58  TYR B CE2 1 
ATOM 1383 C CZ  . TYR B 1 58  ? 131.314 120.924 106.617 1.00 79.80  ? 58  TYR B CZ  1 
ATOM 1384 O OH  . TYR B 1 58  ? 131.442 119.570 106.780 1.00 81.69  ? 58  TYR B OH  1 
ATOM 1385 N N   . SER B 1 59  ? 127.782 125.333 106.967 1.00 94.78  ? 59  SER B N   1 
ATOM 1386 C CA  . SER B 1 59  ? 126.591 124.688 107.505 1.00 93.13  ? 59  SER B CA  1 
ATOM 1387 C C   . SER B 1 59  ? 125.509 124.587 106.442 1.00 94.83  ? 59  SER B C   1 
ATOM 1388 O O   . SER B 1 59  ? 124.870 123.541 106.288 1.00 95.78  ? 59  SER B O   1 
ATOM 1389 C CB  . SER B 1 59  ? 126.082 125.454 108.722 1.00 97.17  ? 59  SER B CB  1 
ATOM 1390 O OG  . SER B 1 59  ? 124.899 124.863 109.224 1.00 103.49 ? 59  SER B OG  1 
ATOM 1391 N N   . LYS B 1 60  ? 125.304 125.664 105.680 1.00 93.46  ? 60  LYS B N   1 
ATOM 1392 C CA  . LYS B 1 60  ? 124.335 125.622 104.590 1.00 90.01  ? 60  LYS B CA  1 
ATOM 1393 C C   . LYS B 1 60  ? 124.746 124.614 103.527 1.00 90.18  ? 60  LYS B C   1 
ATOM 1394 O O   . LYS B 1 60  ? 123.900 123.888 102.996 1.00 95.87  ? 60  LYS B O   1 
ATOM 1395 C CB  . LYS B 1 60  ? 124.171 127.011 103.976 1.00 92.95  ? 60  LYS B CB  1 
ATOM 1396 C CG  . LYS B 1 60  ? 123.526 128.026 104.905 1.00 102.77 ? 60  LYS B CG  1 
ATOM 1397 C CD  . LYS B 1 60  ? 123.404 129.404 104.261 1.00 109.54 ? 60  LYS B CD  1 
ATOM 1398 C CE  . LYS B 1 60  ? 122.231 129.494 103.290 1.00 111.38 ? 60  LYS B CE  1 
ATOM 1399 N NZ  . LYS B 1 60  ? 122.500 128.859 101.969 1.00 110.17 ? 60  LYS B NZ  1 
ATOM 1400 N N   . VAL B 1 61  ? 126.039 124.559 103.202 1.00 92.04  ? 61  VAL B N   1 
ATOM 1401 C CA  . VAL B 1 61  ? 126.512 123.621 102.186 1.00 83.43  ? 61  VAL B CA  1 
ATOM 1402 C C   . VAL B 1 61  ? 126.274 122.184 102.627 1.00 85.72  ? 61  VAL B C   1 
ATOM 1403 O O   . VAL B 1 61  ? 125.792 121.351 101.850 1.00 93.83  ? 61  VAL B O   1 
ATOM 1404 C CB  . VAL B 1 61  ? 127.995 123.879 101.872 1.00 77.25  ? 61  VAL B CB  1 
ATOM 1405 C CG1 . VAL B 1 61  ? 128.654 122.621 101.353 1.00 77.05  ? 61  VAL B CG1 1 
ATOM 1406 C CG2 . VAL B 1 61  ? 128.122 124.994 100.858 1.00 79.48  ? 61  VAL B CG2 1 
ATOM 1407 N N   . LEU B 1 62  ? 126.601 121.869 103.878 1.00 83.83  ? 62  LEU B N   1 
ATOM 1408 C CA  . LEU B 1 62  ? 126.372 120.518 104.369 1.00 88.83  ? 62  LEU B CA  1 
ATOM 1409 C C   . LEU B 1 62  ? 124.887 120.205 104.452 1.00 93.80  ? 62  LEU B C   1 
ATOM 1410 O O   . LEU B 1 62  ? 124.482 119.069 104.186 1.00 104.05 ? 62  LEU B O   1 
ATOM 1411 C CB  . LEU B 1 62  ? 127.037 120.328 105.729 1.00 89.17  ? 62  LEU B CB  1 
ATOM 1412 C CG  . LEU B 1 62  ? 127.825 119.029 105.911 1.00 85.15  ? 62  LEU B CG  1 
ATOM 1413 C CD1 . LEU B 1 62  ? 126.918 117.823 105.840 1.00 85.85  ? 62  LEU B CD1 1 
ATOM 1414 C CD2 . LEU B 1 62  ? 128.912 118.927 104.864 1.00 85.19  ? 62  LEU B CD2 1 
ATOM 1415 N N   . ALA B 1 63  ? 124.062 121.187 104.815 1.00 85.68  ? 63  ALA B N   1 
ATOM 1416 C CA  . ALA B 1 63  ? 122.623 120.958 104.840 1.00 86.93  ? 63  ALA B CA  1 
ATOM 1417 C C   . ALA B 1 63  ? 122.094 120.645 103.448 1.00 95.57  ? 63  ALA B C   1 
ATOM 1418 O O   . ALA B 1 63  ? 121.280 119.731 103.279 1.00 94.79  ? 63  ALA B O   1 
ATOM 1419 C CB  . ALA B 1 63  ? 121.911 122.173 105.426 1.00 93.84  ? 63  ALA B CB  1 
ATOM 1420 N N   . LEU B 1 64  ? 122.550 121.391 102.439 1.00 99.41  ? 64  LEU B N   1 
ATOM 1421 C CA  . LEU B 1 64  ? 122.139 121.114 101.067 1.00 91.61  ? 64  LEU B CA  1 
ATOM 1422 C C   . LEU B 1 64  ? 122.605 119.737 100.620 1.00 95.79  ? 64  LEU B C   1 
ATOM 1423 O O   . LEU B 1 64  ? 121.854 118.999 99.972  1.00 102.69 ? 64  LEU B O   1 
ATOM 1424 C CB  . LEU B 1 64  ? 122.681 122.187 100.128 1.00 82.51  ? 64  LEU B CB  1 
ATOM 1425 C CG  . LEU B 1 64  ? 122.065 123.571 100.285 1.00 85.12  ? 64  LEU B CG  1 
ATOM 1426 C CD1 . LEU B 1 64  ? 122.647 124.527 99.266  1.00 88.38  ? 64  LEU B CD1 1 
ATOM 1427 C CD2 . LEU B 1 64  ? 120.562 123.483 100.140 1.00 89.53  ? 64  LEU B CD2 1 
ATOM 1428 N N   . TYR B 1 65  ? 123.845 119.374 100.953 1.00 90.38  ? 65  TYR B N   1 
ATOM 1429 C CA  . TYR B 1 65  ? 124.348 118.060 100.573 1.00 95.37  ? 65  TYR B CA  1 
ATOM 1430 C C   . TYR B 1 65  ? 123.535 116.950 101.226 1.00 105.73 ? 65  TYR B C   1 
ATOM 1431 O O   . TYR B 1 65  ? 123.219 115.943 100.583 1.00 114.28 ? 65  TYR B O   1 
ATOM 1432 C CB  . TYR B 1 65  ? 125.822 117.929 100.940 1.00 89.80  ? 65  TYR B CB  1 
ATOM 1433 C CG  . TYR B 1 65  ? 126.367 116.534 100.752 1.00 102.12 ? 65  TYR B CG  1 
ATOM 1434 C CD1 . TYR B 1 65  ? 126.693 115.743 101.842 1.00 103.02 ? 65  TYR B CD1 1 
ATOM 1435 C CD2 . TYR B 1 65  ? 126.541 116.002 99.483  1.00 109.80 ? 65  TYR B CD2 1 
ATOM 1436 C CE1 . TYR B 1 65  ? 127.190 114.469 101.674 1.00 110.07 ? 65  TYR B CE1 1 
ATOM 1437 C CE2 . TYR B 1 65  ? 127.040 114.729 99.306  1.00 109.13 ? 65  TYR B CE2 1 
ATOM 1438 C CZ  . TYR B 1 65  ? 127.361 113.967 100.405 1.00 110.29 ? 65  TYR B CZ  1 
ATOM 1439 O OH  . TYR B 1 65  ? 127.855 112.696 100.233 1.00 111.65 ? 65  TYR B OH  1 
ATOM 1440 N N   . ASN B 1 66  ? 123.186 117.115 102.502 1.00 103.18 ? 66  ASN B N   1 
ATOM 1441 C CA  . ASN B 1 66  ? 122.353 116.120 103.168 1.00 104.45 ? 66  ASN B CA  1 
ATOM 1442 C C   . ASN B 1 66  ? 120.971 116.053 102.535 1.00 109.89 ? 66  ASN B C   1 
ATOM 1443 O O   . ASN B 1 66  ? 120.411 114.964 102.365 1.00 115.66 ? 66  ASN B O   1 
ATOM 1444 C CB  . ASN B 1 66  ? 122.242 116.434 104.658 1.00 104.29 ? 66  ASN B CB  1 
ATOM 1445 C CG  . ASN B 1 66  ? 121.403 115.416 105.403 1.00 111.16 ? 66  ASN B CG  1 
ATOM 1446 O OD1 . ASN B 1 66  ? 121.382 114.238 105.052 1.00 116.31 ? 66  ASN B OD1 1 
ATOM 1447 N ND2 . ASN B 1 66  ? 120.699 115.869 106.433 1.00 111.48 ? 66  ASN B ND2 1 
ATOM 1448 N N   . GLN B 1 67  ? 120.403 117.209 102.185 1.00 106.29 ? 67  GLN B N   1 
ATOM 1449 C CA  . GLN B 1 67  ? 119.082 117.228 101.568 1.00 107.04 ? 67  GLN B CA  1 
ATOM 1450 C C   . GLN B 1 67  ? 119.087 116.499 100.233 1.00 108.93 ? 67  GLN B C   1 
ATOM 1451 O O   . GLN B 1 67  ? 118.178 115.713 99.941  1.00 108.52 ? 67  GLN B O   1 
ATOM 1452 C CB  . GLN B 1 67  ? 118.612 118.670 101.384 1.00 103.99 ? 67  GLN B CB  1 
ATOM 1453 C CG  . GLN B 1 67  ? 117.297 118.801 100.638 1.00 102.82 ? 67  GLN B CG  1 
ATOM 1454 C CD  . GLN B 1 67  ? 116.948 120.240 100.320 1.00 102.25 ? 67  GLN B CD  1 
ATOM 1455 O OE1 . GLN B 1 67  ? 117.803 121.123 100.363 1.00 103.18 ? 67  GLN B OE1 1 
ATOM 1456 N NE2 . GLN B 1 67  ? 115.683 120.484 99.999  1.00 99.73  ? 67  GLN B NE2 1 
ATOM 1457 N N   . HIS B 1 68  ? 120.104 116.742 99.411  1.00 107.55 ? 68  HIS B N   1 
ATOM 1458 C CA  . HIS B 1 68  ? 120.167 116.129 98.094  1.00 107.54 ? 68  HIS B CA  1 
ATOM 1459 C C   . HIS B 1 68  ? 120.827 114.758 98.110  1.00 109.91 ? 68  HIS B C   1 
ATOM 1460 O O   . HIS B 1 68  ? 120.774 114.051 97.100  1.00 114.48 ? 68  HIS B O   1 
ATOM 1461 C CB  . HIS B 1 68  ? 120.902 117.058 97.126  1.00 101.53 ? 68  HIS B CB  1 
ATOM 1462 C CG  . HIS B 1 68  ? 120.291 118.422 97.019  1.00 106.33 ? 68  HIS B CG  1 
ATOM 1463 N ND1 . HIS B 1 68  ? 119.095 118.750 97.619  1.00 110.70 ? 68  HIS B ND1 1 
ATOM 1464 C CD2 . HIS B 1 68  ? 120.710 119.540 96.382  1.00 105.51 ? 68  HIS B CD2 1 
ATOM 1465 C CE1 . HIS B 1 68  ? 118.804 120.012 97.358  1.00 107.72 ? 68  HIS B CE1 1 
ATOM 1466 N NE2 . HIS B 1 68  ? 119.768 120.514 96.609  1.00 110.64 ? 68  HIS B NE2 1 
ATOM 1467 N N   . ASN B 1 69  ? 121.446 114.369 99.222  1.00 112.52 ? 69  ASN B N   1 
ATOM 1468 C CA  . ASN B 1 69  ? 122.022 113.035 99.385  1.00 120.16 ? 69  ASN B CA  1 
ATOM 1469 C C   . ASN B 1 69  ? 121.589 112.486 100.736 1.00 130.02 ? 69  ASN B C   1 
ATOM 1470 O O   . ASN B 1 69  ? 122.353 112.499 101.708 1.00 134.04 ? 69  ASN B O   1 
ATOM 1471 C CB  . ASN B 1 69  ? 123.545 113.080 99.260  1.00 112.87 ? 69  ASN B CB  1 
ATOM 1472 C CG  . ASN B 1 69  ? 123.999 113.673 97.946  1.00 109.29 ? 69  ASN B CG  1 
ATOM 1473 O OD1 . ASN B 1 69  ? 123.954 114.886 97.753  1.00 106.38 ? 69  ASN B OD1 1 
ATOM 1474 N ND2 . ASN B 1 69  ? 124.443 112.818 97.033  1.00 111.52 ? 69  ASN B ND2 1 
ATOM 1475 N N   . PRO B 1 70  ? 120.349 112.000 100.834 1.00 131.44 ? 70  PRO B N   1 
ATOM 1476 C CA  . PRO B 1 70  ? 119.839 111.544 102.140 1.00 135.13 ? 70  PRO B CA  1 
ATOM 1477 C C   . PRO B 1 70  ? 120.649 110.420 102.764 1.00 137.71 ? 70  PRO B C   1 
ATOM 1478 O O   . PRO B 1 70  ? 120.784 110.372 103.993 1.00 133.23 ? 70  PRO B O   1 
ATOM 1479 C CB  . PRO B 1 70  ? 118.406 111.100 101.812 1.00 134.69 ? 70  PRO B CB  1 
ATOM 1480 C CG  . PRO B 1 70  ? 118.425 110.801 100.350 1.00 133.94 ? 70  PRO B CG  1 
ATOM 1481 C CD  . PRO B 1 70  ? 119.378 111.785 99.750  1.00 126.34 ? 70  PRO B CD  1 
ATOM 1482 N N   . GLY B 1 71  ? 121.190 109.513 101.956 1.00 136.83 ? 71  GLY B N   1 
ATOM 1483 C CA  . GLY B 1 71  ? 121.988 108.426 102.486 1.00 133.36 ? 71  GLY B CA  1 
ATOM 1484 C C   . GLY B 1 71  ? 123.463 108.760 102.562 1.00 134.88 ? 71  GLY B C   1 
ATOM 1485 O O   . GLY B 1 71  ? 124.294 108.079 101.953 1.00 137.57 ? 71  GLY B O   1 
ATOM 1486 N N   . ALA B 1 72  ? 123.801 109.805 103.310 1.00 132.31 ? 72  ALA B N   1 
ATOM 1487 C CA  . ALA B 1 72  ? 125.175 110.276 103.424 1.00 128.64 ? 72  ALA B CA  1 
ATOM 1488 C C   . ALA B 1 72  ? 125.729 110.189 104.834 1.00 123.12 ? 72  ALA B C   1 
ATOM 1489 O O   . ALA B 1 72  ? 126.948 110.105 105.005 1.00 119.85 ? 72  ALA B O   1 
ATOM 1490 C CB  . ALA B 1 72  ? 125.278 111.725 102.931 1.00 121.71 ? 72  ALA B CB  1 
ATOM 1491 N N   . SER B 1 73  ? 124.868 110.223 105.850 1.00 121.58 ? 73  SER B N   1 
ATOM 1492 C CA  . SER B 1 73  ? 125.213 110.173 107.268 1.00 124.65 ? 73  SER B CA  1 
ATOM 1493 C C   . SER B 1 73  ? 126.027 111.377 107.724 1.00 123.69 ? 73  SER B C   1 
ATOM 1494 O O   . SER B 1 73  ? 126.478 111.398 108.875 1.00 123.88 ? 73  SER B O   1 
ATOM 1495 C CB  . SER B 1 73  ? 125.973 108.893 107.646 1.00 128.51 ? 73  SER B CB  1 
ATOM 1496 O OG  . SER B 1 73  ? 126.315 108.894 109.020 1.00 133.20 ? 73  SER B OG  1 
ATOM 1497 N N   . ALA B 1 74  ? 126.232 112.375 106.872 1.00 118.35 ? 74  ALA B N   1 
ATOM 1498 C CA  . ALA B 1 74  ? 126.942 113.594 107.233 1.00 109.06 ? 74  ALA B CA  1 
ATOM 1499 C C   . ALA B 1 74  ? 125.952 114.748 107.209 1.00 109.56 ? 74  ALA B C   1 
ATOM 1500 O O   . ALA B 1 74  ? 125.318 115.001 106.180 1.00 114.01 ? 74  ALA B O   1 
ATOM 1501 C CB  . ALA B 1 74  ? 128.102 113.856 106.276 1.00 99.54  ? 74  ALA B CB  1 
ATOM 1502 N N   . ALA B 1 75  ? 125.821 115.444 108.335 1.00 102.89 ? 75  ALA B N   1 
ATOM 1503 C CA  . ALA B 1 75  ? 124.872 116.541 108.456 1.00 92.64  ? 75  ALA B CA  1 
ATOM 1504 C C   . ALA B 1 75  ? 125.346 117.466 109.565 1.00 87.49  ? 75  ALA B C   1 
ATOM 1505 O O   . ALA B 1 75  ? 126.070 117.034 110.468 1.00 88.06  ? 75  ALA B O   1 
ATOM 1506 C CB  . ALA B 1 75  ? 123.456 116.024 108.754 1.00 92.17  ? 75  ALA B CB  1 
ATOM 1507 N N   . PRO B 1 76  ? 124.961 118.741 109.522 1.00 90.01  ? 76  PRO B N   1 
ATOM 1508 C CA  . PRO B 1 76  ? 125.285 119.638 110.632 1.00 90.23  ? 76  PRO B CA  1 
ATOM 1509 C C   . PRO B 1 76  ? 124.641 119.157 111.921 1.00 94.25  ? 76  PRO B C   1 
ATOM 1510 O O   . PRO B 1 76  ? 123.585 118.522 111.917 1.00 95.72  ? 76  PRO B O   1 
ATOM 1511 C CB  . PRO B 1 76  ? 124.708 120.984 110.183 1.00 88.73  ? 76  PRO B CB  1 
ATOM 1512 C CG  . PRO B 1 76  ? 124.656 120.895 108.711 1.00 94.33  ? 76  PRO B CG  1 
ATOM 1513 C CD  . PRO B 1 76  ? 124.333 119.462 108.406 1.00 96.42  ? 76  PRO B CD  1 
ATOM 1514 N N   . CYS B 1 77  ? 125.298 119.459 113.034 1.00 93.06  ? 77  CYS B N   1 
ATOM 1515 C CA  . CYS B 1 77  ? 124.890 118.963 114.334 1.00 90.83  ? 77  CYS B CA  1 
ATOM 1516 C C   . CYS B 1 77  ? 124.349 120.103 115.184 1.00 89.81  ? 77  CYS B C   1 
ATOM 1517 O O   . CYS B 1 77  ? 124.608 121.280 114.925 1.00 91.50  ? 77  CYS B O   1 
ATOM 1518 C CB  . CYS B 1 77  ? 126.057 118.279 115.050 1.00 93.32  ? 77  CYS B CB  1 
ATOM 1519 S SG  . CYS B 1 77  ? 125.594 116.789 115.946 1.00 107.61 ? 77  CYS B SG  1 
ATOM 1520 N N   . CYS B 1 78  ? 123.584 119.730 116.205 1.00 87.76  ? 78  CYS B N   1 
ATOM 1521 C CA  . CYS B 1 78  ? 122.968 120.681 117.122 1.00 83.51  ? 78  CYS B CA  1 
ATOM 1522 C C   . CYS B 1 78  ? 123.896 120.880 118.314 1.00 84.53  ? 78  CYS B C   1 
ATOM 1523 O O   . CYS B 1 78  ? 124.124 119.942 119.085 1.00 88.37  ? 78  CYS B O   1 
ATOM 1524 C CB  . CYS B 1 78  ? 121.605 120.156 117.567 1.00 83.91  ? 78  CYS B CB  1 
ATOM 1525 S SG  . CYS B 1 78  ? 120.506 121.336 118.362 1.00 108.91 ? 78  CYS B SG  1 
ATOM 1526 N N   . VAL B 1 79  ? 124.432 122.087 118.466 1.00 78.69  ? 79  VAL B N   1 
ATOM 1527 C CA  . VAL B 1 79  ? 125.454 122.329 119.484 1.00 69.41  ? 79  VAL B CA  1 
ATOM 1528 C C   . VAL B 1 79  ? 125.187 123.662 120.166 1.00 78.17  ? 79  VAL B C   1 
ATOM 1529 O O   . VAL B 1 79  ? 124.587 124.572 119.576 1.00 89.26  ? 79  VAL B O   1 
ATOM 1530 C CB  . VAL B 1 79  ? 126.875 122.298 118.881 1.00 67.74  ? 79  VAL B CB  1 
ATOM 1531 C CG1 . VAL B 1 79  ? 127.287 120.871 118.628 1.00 75.47  ? 79  VAL B CG1 1 
ATOM 1532 C CG2 . VAL B 1 79  ? 126.916 123.109 117.608 1.00 72.19  ? 79  VAL B CG2 1 
ATOM 1533 N N   . PRO B 1 80  ? 125.630 123.811 121.414 1.00 73.23  ? 80  PRO B N   1 
ATOM 1534 C CA  . PRO B 1 80  ? 125.392 125.061 122.141 1.00 73.08  ? 80  PRO B CA  1 
ATOM 1535 C C   . PRO B 1 80  ? 126.060 126.250 121.479 1.00 81.90  ? 80  PRO B C   1 
ATOM 1536 O O   . PRO B 1 80  ? 127.160 126.152 120.934 1.00 87.75  ? 80  PRO B O   1 
ATOM 1537 C CB  . PRO B 1 80  ? 126.007 124.791 123.515 1.00 68.34  ? 80  PRO B CB  1 
ATOM 1538 C CG  . PRO B 1 80  ? 126.033 123.320 123.634 1.00 70.11  ? 80  PRO B CG  1 
ATOM 1539 C CD  . PRO B 1 80  ? 126.274 122.800 122.265 1.00 71.79  ? 80  PRO B CD  1 
ATOM 1540 N N   . GLN B 1 81  ? 125.382 127.393 121.550 1.00 80.18  ? 81  GLN B N   1 
ATOM 1541 C CA  . GLN B 1 81  ? 125.887 128.646 121.010 1.00 88.16  ? 81  GLN B CA  1 
ATOM 1542 C C   . GLN B 1 81  ? 126.248 129.644 122.097 1.00 89.27  ? 81  GLN B C   1 
ATOM 1543 O O   . GLN B 1 81  ? 127.361 130.178 122.106 1.00 92.54  ? 81  GLN B O   1 
ATOM 1544 C CB  . GLN B 1 81  ? 124.857 129.268 120.059 1.00 86.16  ? 81  GLN B CB  1 
ATOM 1545 C CG  . GLN B 1 81  ? 125.293 130.603 119.492 1.00 92.48  ? 81  GLN B CG  1 
ATOM 1546 C CD  . GLN B 1 81  ? 124.329 131.146 118.464 1.00 96.27  ? 81  GLN B CD  1 
ATOM 1547 O OE1 . GLN B 1 81  ? 123.174 130.732 118.398 1.00 99.96  ? 81  GLN B OE1 1 
ATOM 1548 N NE2 . GLN B 1 81  ? 124.802 132.078 117.647 1.00 103.98 ? 81  GLN B NE2 1 
ATOM 1549 N N   . ALA B 1 82  ? 125.325 129.919 123.013 1.00 84.06  ? 82  ALA B N   1 
ATOM 1550 C CA  . ALA B 1 82  ? 125.589 130.755 124.174 1.00 81.00  ? 82  ALA B CA  1 
ATOM 1551 C C   . ALA B 1 82  ? 125.445 129.910 125.429 1.00 73.49  ? 82  ALA B C   1 
ATOM 1552 O O   . ALA B 1 82  ? 124.405 129.280 125.641 1.00 70.65  ? 82  ALA B O   1 
ATOM 1553 C CB  . ALA B 1 82  ? 124.638 131.951 124.225 1.00 83.79  ? 82  ALA B CB  1 
ATOM 1554 N N   . LEU B 1 83  ? 126.488 129.898 126.252 1.00 72.43  ? 83  LEU B N   1 
ATOM 1555 C CA  . LEU B 1 83  ? 126.516 129.120 127.480 1.00 66.67  ? 83  LEU B CA  1 
ATOM 1556 C C   . LEU B 1 83  ? 126.703 130.055 128.666 1.00 67.82  ? 83  LEU B C   1 
ATOM 1557 O O   . LEU B 1 83  ? 127.405 131.065 128.564 1.00 67.62  ? 83  LEU B O   1 
ATOM 1558 C CB  . LEU B 1 83  ? 127.631 128.078 127.447 1.00 53.98  ? 83  LEU B CB  1 
ATOM 1559 C CG  . LEU B 1 83  ? 127.734 127.242 126.177 1.00 53.44  ? 83  LEU B CG  1 
ATOM 1560 C CD1 . LEU B 1 83  ? 128.805 127.794 125.258 1.00 55.30  ? 83  LEU B CD1 1 
ATOM 1561 C CD2 . LEU B 1 83  ? 128.021 125.808 126.520 1.00 51.00  ? 83  LEU B CD2 1 
ATOM 1562 N N   . GLU B 1 84  ? 126.070 129.714 129.794 1.00 64.11  ? 84  GLU B N   1 
ATOM 1563 C CA  . GLU B 1 84  ? 126.074 130.619 130.930 1.00 63.09  ? 84  GLU B CA  1 
ATOM 1564 C C   . GLU B 1 84  ? 126.744 129.983 132.143 1.00 60.75  ? 84  GLU B C   1 
ATOM 1565 O O   . GLU B 1 84  ? 126.641 128.769 132.341 1.00 59.95  ? 84  GLU B O   1 
ATOM 1566 C CB  . GLU B 1 84  ? 124.645 131.034 131.300 1.00 65.27  ? 84  GLU B CB  1 
ATOM 1567 C CG  . GLU B 1 84  ? 123.932 131.836 130.225 1.00 76.69  ? 84  GLU B CG  1 
ATOM 1568 C CD  . GLU B 1 84  ? 124.608 133.161 129.934 1.00 83.01  ? 84  GLU B CD  1 
ATOM 1569 O OE1 . GLU B 1 84  ? 125.231 133.731 130.853 1.00 81.60  ? 84  GLU B OE1 1 
ATOM 1570 O OE2 . GLU B 1 84  ? 124.519 133.635 128.782 1.00 85.52  ? 84  GLU B OE2 1 
ATOM 1571 N N   . PRO B 1 85  ? 127.422 130.777 132.971 1.00 58.90  ? 85  PRO B N   1 
ATOM 1572 C CA  . PRO B 1 85  ? 128.145 130.211 134.112 1.00 48.23  ? 85  PRO B CA  1 
ATOM 1573 C C   . PRO B 1 85  ? 127.202 129.674 135.174 1.00 45.71  ? 85  PRO B C   1 
ATOM 1574 O O   . PRO B 1 85  ? 126.023 130.022 135.222 1.00 52.99  ? 85  PRO B O   1 
ATOM 1575 C CB  . PRO B 1 85  ? 128.952 131.399 134.644 1.00 50.87  ? 85  PRO B CB  1 
ATOM 1576 C CG  . PRO B 1 85  ? 128.996 132.372 133.521 1.00 52.47  ? 85  PRO B CG  1 
ATOM 1577 C CD  . PRO B 1 85  ? 127.703 132.210 132.805 1.00 60.80  ? 85  PRO B CD  1 
ATOM 1578 N N   . LEU B 1 86  ? 127.741 128.810 136.031 1.00 44.27  ? 86  LEU B N   1 
ATOM 1579 C CA  . LEU B 1 86  ? 127.018 128.281 137.181 1.00 48.51  ? 86  LEU B CA  1 
ATOM 1580 C C   . LEU B 1 86  ? 127.741 128.669 138.462 1.00 60.54  ? 86  LEU B C   1 
ATOM 1581 O O   . LEU B 1 86  ? 128.901 128.267 138.652 1.00 64.56  ? 86  LEU B O   1 
ATOM 1582 C CB  . LEU B 1 86  ? 126.888 126.766 137.103 1.00 44.05  ? 86  LEU B CB  1 
ATOM 1583 C CG  . LEU B 1 86  ? 126.216 126.191 138.344 1.00 45.94  ? 86  LEU B CG  1 
ATOM 1584 C CD1 . LEU B 1 86  ? 124.735 126.466 138.293 1.00 48.23  ? 86  LEU B CD1 1 
ATOM 1585 C CD2 . LEU B 1 86  ? 126.479 124.714 138.484 1.00 54.33  ? 86  LEU B CD2 1 
ATOM 1586 N N   . PRO B 1 87  ? 127.134 129.451 139.351 1.00 58.71  ? 87  PRO B N   1 
ATOM 1587 C CA  . PRO B 1 87  ? 127.769 129.716 140.645 1.00 51.30  ? 87  PRO B CA  1 
ATOM 1588 C C   . PRO B 1 87  ? 127.549 128.566 141.614 1.00 50.85  ? 87  PRO B C   1 
ATOM 1589 O O   . PRO B 1 87  ? 126.423 128.116 141.831 1.00 52.34  ? 87  PRO B O   1 
ATOM 1590 C CB  . PRO B 1 87  ? 127.067 130.990 141.129 1.00 50.96  ? 87  PRO B CB  1 
ATOM 1591 C CG  . PRO B 1 87  ? 126.405 131.557 139.911 1.00 56.17  ? 87  PRO B CG  1 
ATOM 1592 C CD  . PRO B 1 87  ? 126.022 130.375 139.096 1.00 49.56  ? 87  PRO B CD  1 
ATOM 1593 N N   . ILE B 1 88  ? 128.648 128.095 142.203 1.00 50.57  ? 88  ILE B N   1 
ATOM 1594 C CA  . ILE B 1 88  ? 128.634 126.989 143.147 1.00 52.28  ? 88  ILE B CA  1 
ATOM 1595 C C   . ILE B 1 88  ? 129.320 127.426 144.432 1.00 58.78  ? 88  ILE B C   1 
ATOM 1596 O O   . ILE B 1 88  ? 130.081 128.395 144.464 1.00 60.00  ? 88  ILE B O   1 
ATOM 1597 C CB  . ILE B 1 88  ? 129.331 125.733 142.600 1.00 54.86  ? 88  ILE B CB  1 
ATOM 1598 C CG1 . ILE B 1 88  ? 130.819 126.010 142.435 1.00 62.80  ? 88  ILE B CG1 1 
ATOM 1599 C CG2 . ILE B 1 88  ? 128.731 125.319 141.285 1.00 55.52  ? 88  ILE B CG2 1 
ATOM 1600 C CD1 . ILE B 1 88  ? 131.639 124.780 142.247 1.00 62.82  ? 88  ILE B CD1 1 
ATOM 1601 N N   . VAL B 1 89  ? 129.046 126.681 145.497 1.00 60.52  ? 89  VAL B N   1 
ATOM 1602 C CA  . VAL B 1 89  ? 129.653 126.903 146.802 1.00 61.22  ? 89  VAL B CA  1 
ATOM 1603 C C   . VAL B 1 89  ? 130.430 125.650 147.178 1.00 70.81  ? 89  VAL B C   1 
ATOM 1604 O O   . VAL B 1 89  ? 129.863 124.551 147.231 1.00 74.63  ? 89  VAL B O   1 
ATOM 1605 C CB  . VAL B 1 89  ? 128.600 127.238 147.866 1.00 54.64  ? 89  VAL B CB  1 
ATOM 1606 C CG1 . VAL B 1 89  ? 129.210 127.173 149.245 1.00 58.21  ? 89  VAL B CG1 1 
ATOM 1607 C CG2 . VAL B 1 89  ? 128.022 128.609 147.611 1.00 57.77  ? 89  VAL B CG2 1 
ATOM 1608 N N   . TYR B 1 90  ? 131.722 125.816 147.443 1.00 71.08  ? 90  TYR B N   1 
ATOM 1609 C CA  . TYR B 1 90  ? 132.591 124.717 147.836 1.00 62.81  ? 90  TYR B CA  1 
ATOM 1610 C C   . TYR B 1 90  ? 133.412 125.142 149.042 1.00 68.11  ? 90  TYR B C   1 
ATOM 1611 O O   . TYR B 1 90  ? 133.684 126.326 149.234 1.00 74.01  ? 90  TYR B O   1 
ATOM 1612 C CB  . TYR B 1 90  ? 133.519 124.302 146.703 1.00 54.57  ? 90  TYR B CB  1 
ATOM 1613 C CG  . TYR B 1 90  ? 134.545 125.349 146.366 1.00 56.16  ? 90  TYR B CG  1 
ATOM 1614 C CD1 . TYR B 1 90  ? 134.217 126.434 145.580 1.00 60.52  ? 90  TYR B CD1 1 
ATOM 1615 C CD2 . TYR B 1 90  ? 135.842 125.251 146.830 1.00 60.07  ? 90  TYR B CD2 1 
ATOM 1616 C CE1 . TYR B 1 90  ? 135.147 127.392 145.270 1.00 63.31  ? 90  TYR B CE1 1 
ATOM 1617 C CE2 . TYR B 1 90  ? 136.778 126.207 146.524 1.00 64.59  ? 90  TYR B CE2 1 
ATOM 1618 C CZ  . TYR B 1 90  ? 136.424 127.275 145.742 1.00 66.24  ? 90  TYR B CZ  1 
ATOM 1619 O OH  . TYR B 1 90  ? 137.348 128.238 145.427 1.00 81.30  ? 90  TYR B OH  1 
ATOM 1620 N N   . TYR B 1 91  ? 133.816 124.170 149.848 1.00 66.16  ? 91  TYR B N   1 
ATOM 1621 C CA  . TYR B 1 91  ? 134.501 124.440 151.105 1.00 66.91  ? 91  TYR B CA  1 
ATOM 1622 C C   . TYR B 1 91  ? 135.999 124.227 150.935 1.00 69.75  ? 91  TYR B C   1 
ATOM 1623 O O   . TYR B 1 91  ? 136.427 123.157 150.495 1.00 76.91  ? 91  TYR B O   1 
ATOM 1624 C CB  . TYR B 1 91  ? 133.966 123.535 152.213 1.00 72.52  ? 91  TYR B CB  1 
ATOM 1625 C CG  . TYR B 1 91  ? 132.699 124.020 152.871 1.00 69.09  ? 91  TYR B CG  1 
ATOM 1626 C CD1 . TYR B 1 91  ? 132.748 124.866 153.964 1.00 67.83  ? 91  TYR B CD1 1 
ATOM 1627 C CD2 . TYR B 1 91  ? 131.457 123.619 152.412 1.00 68.83  ? 91  TYR B CD2 1 
ATOM 1628 C CE1 . TYR B 1 91  ? 131.600 125.305 154.577 1.00 67.31  ? 91  TYR B CE1 1 
ATOM 1629 C CE2 . TYR B 1 91  ? 130.300 124.057 153.020 1.00 67.61  ? 91  TYR B CE2 1 
ATOM 1630 C CZ  . TYR B 1 91  ? 130.381 124.901 154.102 1.00 67.73  ? 91  TYR B CZ  1 
ATOM 1631 O OH  . TYR B 1 91  ? 129.236 125.345 154.718 1.00 65.56  ? 91  TYR B OH  1 
ATOM 1632 N N   . VAL B 1 92  ? 136.791 125.235 151.289 1.00 71.94  ? 92  VAL B N   1 
ATOM 1633 C CA  . VAL B 1 92  ? 138.234 125.086 151.438 1.00 72.71  ? 92  VAL B CA  1 
ATOM 1634 C C   . VAL B 1 92  ? 138.529 125.107 152.931 1.00 74.85  ? 92  VAL B C   1 
ATOM 1635 O O   . VAL B 1 92  ? 138.274 126.106 153.614 1.00 76.50  ? 92  VAL B O   1 
ATOM 1636 C CB  . VAL B 1 92  ? 139.011 126.181 150.694 1.00 69.99  ? 92  VAL B CB  1 
ATOM 1637 C CG1 . VAL B 1 92  ? 139.105 125.856 149.225 1.00 65.90  ? 92  VAL B CG1 1 
ATOM 1638 C CG2 . VAL B 1 92  ? 138.344 127.525 150.878 1.00 76.85  ? 92  VAL B CG2 1 
ATOM 1639 N N   . GLY B 1 93  ? 139.061 124.012 153.445 1.00 74.91  ? 93  GLY B N   1 
ATOM 1640 C CA  . GLY B 1 93  ? 139.213 123.902 154.883 1.00 78.84  ? 93  GLY B CA  1 
ATOM 1641 C C   . GLY B 1 93  ? 137.851 123.980 155.533 1.00 73.43  ? 93  GLY B C   1 
ATOM 1642 O O   . GLY B 1 93  ? 136.932 123.232 155.190 1.00 76.51  ? 93  GLY B O   1 
ATOM 1643 N N   . ARG B 1 94  ? 137.697 124.898 156.480 1.00 74.79  ? 94  ARG B N   1 
ATOM 1644 C CA  . ARG B 1 94  ? 136.412 125.141 157.116 1.00 82.26  ? 94  ARG B CA  1 
ATOM 1645 C C   . ARG B 1 94  ? 135.702 126.368 156.565 1.00 73.51  ? 94  ARG B C   1 
ATOM 1646 O O   . ARG B 1 94  ? 134.666 126.760 157.106 1.00 68.09  ? 94  ARG B O   1 
ATOM 1647 C CB  . ARG B 1 94  ? 136.593 125.282 158.628 1.00 86.91  ? 94  ARG B CB  1 
ATOM 1648 C CG  . ARG B 1 94  ? 137.804 126.098 159.027 1.00 80.41  ? 94  ARG B CG  1 
ATOM 1649 C CD  . ARG B 1 94  ? 137.978 126.097 160.530 1.00 81.12  ? 94  ARG B CD  1 
ATOM 1650 N NE  . ARG B 1 94  ? 137.689 124.787 161.096 1.00 91.13  ? 94  ARG B NE  1 
ATOM 1651 C CZ  . ARG B 1 94  ? 137.868 124.465 162.369 1.00 101.77 ? 94  ARG B CZ  1 
ATOM 1652 N NH1 . ARG B 1 94  ? 138.360 125.333 163.238 1.00 103.28 ? 94  ARG B NH1 1 
ATOM 1653 N NH2 . ARG B 1 94  ? 137.545 123.243 162.781 1.00 106.08 ? 94  ARG B NH2 1 
ATOM 1654 N N   . LYS B 1 95  ? 136.226 126.978 155.504 1.00 67.22  ? 95  LYS B N   1 
ATOM 1655 C CA  . LYS B 1 95  ? 135.663 128.211 154.984 1.00 66.00  ? 95  LYS B CA  1 
ATOM 1656 C C   . LYS B 1 95  ? 134.935 127.940 153.680 1.00 75.00  ? 95  LYS B C   1 
ATOM 1657 O O   . LYS B 1 95  ? 135.564 127.463 152.723 1.00 78.92  ? 95  LYS B O   1 
ATOM 1658 C CB  . LYS B 1 95  ? 136.760 129.243 154.768 1.00 68.03  ? 95  LYS B CB  1 
ATOM 1659 C CG  . LYS B 1 95  ? 136.250 130.595 154.312 1.00 76.46  ? 95  LYS B CG  1 
ATOM 1660 C CD  . LYS B 1 95  ? 137.333 131.657 154.409 1.00 85.72  ? 95  LYS B CD  1 
ATOM 1661 C CE  . LYS B 1 95  ? 137.774 131.865 155.849 1.00 81.55  ? 95  LYS B CE  1 
ATOM 1662 N NZ  . LYS B 1 95  ? 136.641 132.295 156.713 1.00 76.12  ? 95  LYS B NZ  1 
ATOM 1663 N N   . PRO B 1 96  ? 133.631 128.195 153.591 1.00 75.56  ? 96  PRO B N   1 
ATOM 1664 C CA  . PRO B 1 96  ? 132.949 128.093 152.298 1.00 66.70  ? 96  PRO B CA  1 
ATOM 1665 C C   . PRO B 1 96  ? 133.331 129.250 151.392 1.00 66.30  ? 96  PRO B C   1 
ATOM 1666 O O   . PRO B 1 96  ? 133.703 130.332 151.852 1.00 72.12  ? 96  PRO B O   1 
ATOM 1667 C CB  . PRO B 1 96  ? 131.466 128.145 152.679 1.00 59.45  ? 96  PRO B CB  1 
ATOM 1668 C CG  . PRO B 1 96  ? 131.446 128.939 153.918 1.00 59.39  ? 96  PRO B CG  1 
ATOM 1669 C CD  . PRO B 1 96  ? 132.713 128.614 154.661 1.00 69.25  ? 96  PRO B CD  1 
ATOM 1670 N N   . LYS B 1 97  ? 133.234 129.014 150.089 1.00 58.68  ? 97  LYS B N   1 
ATOM 1671 C CA  . LYS B 1 97  ? 133.607 130.002 149.094 1.00 61.53  ? 97  LYS B CA  1 
ATOM 1672 C C   . LYS B 1 97  ? 132.751 129.797 147.856 1.00 65.18  ? 97  LYS B C   1 
ATOM 1673 O O   . LYS B 1 97  ? 132.227 128.704 147.621 1.00 67.35  ? 97  LYS B O   1 
ATOM 1674 C CB  . LYS B 1 97  ? 135.095 129.899 148.747 1.00 63.28  ? 97  LYS B CB  1 
ATOM 1675 C CG  . LYS B 1 97  ? 135.680 131.152 148.135 1.00 67.78  ? 97  LYS B CG  1 
ATOM 1676 C CD  . LYS B 1 97  ? 137.169 131.003 147.912 1.00 68.12  ? 97  LYS B CD  1 
ATOM 1677 C CE  . LYS B 1 97  ? 137.875 130.595 149.190 1.00 61.67  ? 97  LYS B CE  1 
ATOM 1678 N NZ  . LYS B 1 97  ? 137.642 131.558 150.298 1.00 55.82  ? 97  LYS B NZ  1 
ATOM 1679 N N   . VAL B 1 98  ? 132.613 130.856 147.064 1.00 64.43  ? 98  VAL B N   1 
ATOM 1680 C CA  . VAL B 1 98  ? 131.740 130.866 145.897 1.00 63.95  ? 98  VAL B CA  1 
ATOM 1681 C C   . VAL B 1 98  ? 132.596 130.955 144.645 1.00 66.62  ? 98  VAL B C   1 
ATOM 1682 O O   . VAL B 1 98  ? 133.402 131.881 144.497 1.00 66.20  ? 98  VAL B O   1 
ATOM 1683 C CB  . VAL B 1 98  ? 130.734 132.026 145.957 1.00 60.76  ? 98  VAL B CB  1 
ATOM 1684 C CG1 . VAL B 1 98  ? 130.026 132.181 144.631 1.00 59.58  ? 98  VAL B CG1 1 
ATOM 1685 C CG2 . VAL B 1 98  ? 129.728 131.782 147.055 1.00 63.68  ? 98  VAL B CG2 1 
ATOM 1686 N N   . GLU B 1 99  ? 132.408 129.997 143.742 1.00 64.60  ? 99  GLU B N   1 
ATOM 1687 C CA  . GLU B 1 99  ? 133.104 129.949 142.467 1.00 62.63  ? 99  GLU B CA  1 
ATOM 1688 C C   . GLU B 1 99  ? 132.084 130.038 141.344 1.00 62.70  ? 99  GLU B C   1 
ATOM 1689 O O   . GLU B 1 99  ? 130.924 129.666 141.516 1.00 62.19  ? 99  GLU B O   1 
ATOM 1690 C CB  . GLU B 1 99  ? 133.913 128.660 142.327 1.00 67.23  ? 99  GLU B CB  1 
ATOM 1691 C CG  . GLU B 1 99  ? 135.112 128.779 141.416 1.00 75.93  ? 99  GLU B CG  1 
ATOM 1692 C CD  . GLU B 1 99  ? 136.156 129.720 141.971 1.00 86.12  ? 99  GLU B CD  1 
ATOM 1693 O OE1 . GLU B 1 99  ? 136.496 129.595 143.166 1.00 79.59  ? 99  GLU B OE1 1 
ATOM 1694 O OE2 . GLU B 1 99  ? 136.627 130.595 141.215 1.00 100.86 ? 99  GLU B OE2 1 
ATOM 1695 N N   . GLN B 1 100 ? 132.507 130.544 140.193 1.00 64.34  ? 100 GLN B N   1 
ATOM 1696 C CA  . GLN B 1 100 ? 131.628 130.637 139.030 1.00 63.86  ? 100 GLN B CA  1 
ATOM 1697 C C   . GLN B 1 100 ? 132.170 129.730 137.933 1.00 67.27  ? 100 GLN B C   1 
ATOM 1698 O O   . GLN B 1 100 ? 132.992 130.156 137.119 1.00 76.96  ? 100 GLN B O   1 
ATOM 1699 C CB  . GLN B 1 100 ? 131.501 132.077 138.548 1.00 65.15  ? 100 GLN B CB  1 
ATOM 1700 C CG  . GLN B 1 100 ? 130.603 132.930 139.422 1.00 71.33  ? 100 GLN B CG  1 
ATOM 1701 C CD  . GLN B 1 100 ? 129.974 134.077 138.664 1.00 76.37  ? 100 GLN B CD  1 
ATOM 1702 O OE1 . GLN B 1 100 ? 130.377 134.394 137.545 1.00 77.43  ? 100 GLN B OE1 1 
ATOM 1703 N NE2 . GLN B 1 100 ? 128.974 134.704 139.267 1.00 78.50  ? 100 GLN B NE2 1 
ATOM 1704 N N   . LEU B 1 101 ? 131.706 128.483 137.906 1.00 62.39  ? 101 LEU B N   1 
ATOM 1705 C CA  . LEU B 1 101 ? 132.131 127.545 136.875 1.00 57.87  ? 101 LEU B CA  1 
ATOM 1706 C C   . LEU B 1 101 ? 131.544 127.981 135.542 1.00 59.71  ? 101 LEU B C   1 
ATOM 1707 O O   . LEU B 1 101 ? 130.356 127.769 135.279 1.00 59.58  ? 101 LEU B O   1 
ATOM 1708 C CB  . LEU B 1 101 ? 131.681 126.135 137.230 1.00 55.42  ? 101 LEU B CB  1 
ATOM 1709 C CG  . LEU B 1 101 ? 132.134 125.611 138.584 1.00 53.46  ? 101 LEU B CG  1 
ATOM 1710 C CD1 . LEU B 1 101 ? 131.704 124.173 138.749 1.00 53.32  ? 101 LEU B CD1 1 
ATOM 1711 C CD2 . LEU B 1 101 ? 133.630 125.742 138.698 1.00 59.26  ? 101 LEU B CD2 1 
ATOM 1712 N N   . SER B 1 102 ? 132.370 128.586 134.698 1.00 56.56  ? 102 SER B N   1 
ATOM 1713 C CA  . SER B 1 102 ? 131.891 129.179 133.461 1.00 50.64  ? 102 SER B CA  1 
ATOM 1714 C C   . SER B 1 102 ? 131.577 128.114 132.420 1.00 48.10  ? 102 SER B C   1 
ATOM 1715 O O   . SER B 1 102 ? 132.144 127.019 132.429 1.00 45.79  ? 102 SER B O   1 
ATOM 1716 C CB  . SER B 1 102 ? 132.922 130.154 132.909 1.00 49.03  ? 102 SER B CB  1 
ATOM 1717 O OG  . SER B 1 102 ? 134.209 129.578 132.940 1.00 61.69  ? 102 SER B OG  1 
ATOM 1718 N N   . ASN B 1 103 ? 130.659 128.457 131.516 1.00 49.58  ? 103 ASN B N   1 
ATOM 1719 C CA  . ASN B 1 103 ? 130.233 127.594 130.418 1.00 45.21  ? 103 ASN B CA  1 
ATOM 1720 C C   . ASN B 1 103 ? 129.748 126.240 130.934 1.00 44.72  ? 103 ASN B C   1 
ATOM 1721 O O   . ASN B 1 103 ? 130.315 125.191 130.637 1.00 57.34  ? 103 ASN B O   1 
ATOM 1722 C CB  . ASN B 1 103 ? 131.353 127.424 129.391 1.00 44.21  ? 103 ASN B CB  1 
ATOM 1723 C CG  . ASN B 1 103 ? 131.601 128.678 128.598 1.00 46.18  ? 103 ASN B CG  1 
ATOM 1724 O OD1 . ASN B 1 103 ? 130.727 129.530 128.480 1.00 47.42  ? 103 ASN B OD1 1 
ATOM 1725 N ND2 . ASN B 1 103 ? 132.794 128.798 128.039 1.00 45.01  ? 103 ASN B ND2 1 
ATOM 1726 N N   . MET B 1 104 ? 128.675 126.282 131.717 1.00 38.63  ? 104 MET B N   1 
ATOM 1727 C CA  . MET B 1 104 ? 128.057 125.073 132.228 1.00 33.56  ? 104 MET B CA  1 
ATOM 1728 C C   . MET B 1 104 ? 126.570 124.968 131.941 1.00 49.09  ? 104 MET B C   1 
ATOM 1729 O O   . MET B 1 104 ? 126.041 123.853 131.942 1.00 54.89  ? 104 MET B O   1 
ATOM 1730 C CB  . MET B 1 104 ? 128.270 124.957 133.741 1.00 31.87  ? 104 MET B CB  1 
ATOM 1731 C CG  . MET B 1 104 ? 129.658 124.560 134.127 1.00 33.55  ? 104 MET B CG  1 
ATOM 1732 S SD  . MET B 1 104 ? 129.629 123.414 135.501 1.00 46.65  ? 104 MET B SD  1 
ATOM 1733 C CE  . MET B 1 104 ? 131.313 122.847 135.440 1.00 65.78  ? 104 MET B CE  1 
ATOM 1734 N N   . ILE B 1 105 ? 125.881 126.079 131.705 1.00 57.66  ? 105 ILE B N   1 
ATOM 1735 C CA  . ILE B 1 105 ? 124.453 126.084 131.421 1.00 54.96  ? 105 ILE B CA  1 
ATOM 1736 C C   . ILE B 1 105 ? 124.263 126.565 129.994 1.00 57.70  ? 105 ILE B C   1 
ATOM 1737 O O   . ILE B 1 105 ? 124.760 127.635 129.627 1.00 65.73  ? 105 ILE B O   1 
ATOM 1738 C CB  . ILE B 1 105 ? 123.679 126.981 132.402 1.00 58.49  ? 105 ILE B CB  1 
ATOM 1739 C CG1 . ILE B 1 105 ? 123.998 126.603 133.845 1.00 56.30  ? 105 ILE B CG1 1 
ATOM 1740 C CG2 . ILE B 1 105 ? 122.190 126.869 132.157 1.00 66.76  ? 105 ILE B CG2 1 
ATOM 1741 C CD1 . ILE B 1 105 ? 123.237 127.411 134.861 1.00 53.52  ? 105 ILE B CD1 1 
ATOM 1742 N N   . VAL B 1 106 ? 123.546 125.782 129.195 1.00 61.37  ? 106 VAL B N   1 
ATOM 1743 C CA  . VAL B 1 106 ? 123.316 126.105 127.792 1.00 66.45  ? 106 VAL B CA  1 
ATOM 1744 C C   . VAL B 1 106 ? 122.044 126.931 127.677 1.00 77.05  ? 106 VAL B C   1 
ATOM 1745 O O   . VAL B 1 106 ? 120.972 126.506 128.119 1.00 79.68  ? 106 VAL B O   1 
ATOM 1746 C CB  . VAL B 1 106 ? 123.220 124.835 126.939 1.00 57.41  ? 106 VAL B CB  1 
ATOM 1747 C CG1 . VAL B 1 106 ? 122.766 125.182 125.543 1.00 60.76  ? 106 VAL B CG1 1 
ATOM 1748 C CG2 . VAL B 1 106 ? 124.555 124.143 126.899 1.00 56.64  ? 106 VAL B CG2 1 
ATOM 1749 N N   . ARG B 1 107 ? 122.160 128.111 127.069 1.00 77.04  ? 107 ARG B N   1 
ATOM 1750 C CA  . ARG B 1 107 ? 121.028 129.005 126.904 1.00 80.82  ? 107 ARG B CA  1 
ATOM 1751 C C   . ARG B 1 107 ? 120.451 128.999 125.496 1.00 90.41  ? 107 ARG B C   1 
ATOM 1752 O O   . ARG B 1 107 ? 119.288 129.374 125.325 1.00 98.79  ? 107 ARG B O   1 
ATOM 1753 C CB  . ARG B 1 107 ? 121.433 130.439 127.282 1.00 82.94  ? 107 ARG B CB  1 
ATOM 1754 C CG  . ARG B 1 107 ? 120.282 131.430 127.411 1.00 93.09  ? 107 ARG B CG  1 
ATOM 1755 C CD  . ARG B 1 107 ? 120.010 131.835 128.861 1.00 94.95  ? 107 ARG B CD  1 
ATOM 1756 N NE  . ARG B 1 107 ? 119.278 130.820 129.612 1.00 97.02  ? 107 ARG B NE  1 
ATOM 1757 C CZ  . ARG B 1 107 ? 119.753 130.176 130.670 1.00 95.99  ? 107 ARG B CZ  1 
ATOM 1758 N NH1 . ARG B 1 107 ? 120.963 130.422 131.143 1.00 89.06  ? 107 ARG B NH1 1 
ATOM 1759 N NH2 . ARG B 1 107 ? 118.991 129.267 131.273 1.00 91.58  ? 107 ARG B NH2 1 
ATOM 1760 N N   . SER B 1 108 ? 121.217 128.576 124.493 1.00 83.71  ? 108 SER B N   1 
ATOM 1761 C CA  . SER B 1 108 ? 120.748 128.586 123.115 1.00 85.89  ? 108 SER B CA  1 
ATOM 1762 C C   . SER B 1 108 ? 121.545 127.583 122.295 1.00 86.15  ? 108 SER B C   1 
ATOM 1763 O O   . SER B 1 108 ? 122.693 127.274 122.615 1.00 85.89  ? 108 SER B O   1 
ATOM 1764 C CB  . SER B 1 108 ? 120.869 129.982 122.500 1.00 94.32  ? 108 SER B CB  1 
ATOM 1765 O OG  . SER B 1 108 ? 120.647 129.939 121.105 1.00 103.79 ? 108 SER B OG  1 
ATOM 1766 N N   . CYS B 1 109 ? 120.939 127.103 121.213 1.00 90.58  ? 109 CYS B N   1 
ATOM 1767 C CA  . CYS B 1 109 ? 121.554 126.104 120.351 1.00 87.25  ? 109 CYS B CA  1 
ATOM 1768 C C   . CYS B 1 109 ? 121.653 126.613 118.921 1.00 89.45  ? 109 CYS B C   1 
ATOM 1769 O O   . CYS B 1 109 ? 120.988 127.578 118.539 1.00 103.65 ? 109 CYS B O   1 
ATOM 1770 C CB  . CYS B 1 109 ? 120.770 124.800 120.368 1.00 86.96  ? 109 CYS B CB  1 
ATOM 1771 S SG  . CYS B 1 109 ? 120.668 124.061 121.992 1.00 116.18 ? 109 CYS B SG  1 
ATOM 1772 N N   . LYS B 1 110 ? 122.494 125.947 118.135 1.00 80.96  ? 110 LYS B N   1 
ATOM 1773 C CA  . LYS B 1 110 ? 122.720 126.312 116.747 1.00 83.25  ? 110 LYS B CA  1 
ATOM 1774 C C   . LYS B 1 110 ? 123.053 125.062 115.950 1.00 90.60  ? 110 LYS B C   1 
ATOM 1775 O O   . LYS B 1 110 ? 123.422 124.022 116.504 1.00 92.74  ? 110 LYS B O   1 
ATOM 1776 C CB  . LYS B 1 110 ? 123.852 127.334 116.605 1.00 84.14  ? 110 LYS B CB  1 
ATOM 1777 C CG  . LYS B 1 110 ? 125.213 126.794 117.001 1.00 88.49  ? 110 LYS B CG  1 
ATOM 1778 C CD  . LYS B 1 110 ? 126.297 127.843 116.841 1.00 93.32  ? 110 LYS B CD  1 
ATOM 1779 C CE  . LYS B 1 110 ? 127.628 127.349 117.380 1.00 94.15  ? 110 LYS B CE  1 
ATOM 1780 N NZ  . LYS B 1 110 ? 128.125 126.163 116.637 1.00 90.95  ? 110 LYS B NZ  1 
ATOM 1781 N N   . CYS B 1 111 ? 122.916 125.177 114.635 1.00 92.65  ? 111 CYS B N   1 
ATOM 1782 C CA  . CYS B 1 111 ? 123.209 124.093 113.708 1.00 89.53  ? 111 CYS B CA  1 
ATOM 1783 C C   . CYS B 1 111 ? 124.548 124.364 113.041 1.00 95.40  ? 111 CYS B C   1 
ATOM 1784 O O   . CYS B 1 111 ? 124.702 125.369 112.341 1.00 103.68 ? 111 CYS B O   1 
ATOM 1785 C CB  . CYS B 1 111 ? 122.107 123.961 112.659 1.00 99.84  ? 111 CYS B CB  1 
ATOM 1786 S SG  . CYS B 1 111 ? 120.558 123.292 113.281 1.00 117.81 ? 111 CYS B SG  1 
ATOM 1787 N N   . SER B 1 112 ? 125.505 123.470 113.253 1.00 95.21  ? 112 SER B N   1 
ATOM 1788 C CA  . SER B 1 112 ? 126.800 123.568 112.595 1.00 95.56  ? 112 SER B CA  1 
ATOM 1789 C C   . SER B 1 112 ? 127.469 122.205 112.562 1.00 95.21  ? 112 SER B C   1 
ATOM 1790 O O   . SER B 1 112 ? 127.348 121.433 113.509 1.00 92.49  ? 112 SER B O   1 
ATOM 1791 C CB  . SER B 1 112 ? 127.701 124.579 113.303 1.00 93.55  ? 112 SER B CB  1 
ATOM 1792 O OG  . SER B 1 112 ? 128.202 124.051 114.518 1.00 95.79  ? 112 SER B OG  1 
ATOM 1793 O OXT . SER B 1 112 ? 128.143 121.846 111.599 1.00 98.74  ? 112 SER B OXT 1 
ATOM 1794 N N   . CYS C 2 4   ? 160.730 147.068 129.160 1.00 132.70 ? 4   CYS C N   1 
ATOM 1795 C CA  . CYS C 2 4   ? 160.219 147.923 130.225 1.00 140.30 ? 4   CYS C CA  1 
ATOM 1796 C C   . CYS C 2 4   ? 160.649 147.403 131.591 1.00 143.92 ? 4   CYS C C   1 
ATOM 1797 O O   . CYS C 2 4   ? 161.534 146.555 131.695 1.00 143.14 ? 4   CYS C O   1 
ATOM 1798 C CB  . CYS C 2 4   ? 158.694 148.012 130.160 1.00 140.90 ? 4   CYS C CB  1 
ATOM 1799 S SG  . CYS C 2 4   ? 157.845 146.535 130.774 1.00 151.39 ? 4   CYS C SG  1 
ATOM 1800 N N   . GLU C 2 5   ? 160.014 147.921 132.640 1.00 141.55 ? 5   GLU C N   1 
ATOM 1801 C CA  . GLU C 2 5   ? 160.264 147.490 134.007 1.00 136.28 ? 5   GLU C CA  1 
ATOM 1802 C C   . GLU C 2 5   ? 158.936 147.256 134.708 1.00 131.77 ? 5   GLU C C   1 
ATOM 1803 O O   . GLU C 2 5   ? 158.013 148.066 134.588 1.00 130.55 ? 5   GLU C O   1 
ATOM 1804 C CB  . GLU C 2 5   ? 161.089 148.525 134.786 1.00 135.89 ? 5   GLU C CB  1 
ATOM 1805 C CG  . GLU C 2 5   ? 162.467 148.812 134.207 1.00 139.57 ? 5   GLU C CG  1 
ATOM 1806 C CD  . GLU C 2 5   ? 162.427 149.773 133.033 1.00 143.46 ? 5   GLU C CD  1 
ATOM 1807 O OE1 . GLU C 2 5   ? 161.331 150.279 132.712 1.00 142.05 ? 5   GLU C OE1 1 
ATOM 1808 O OE2 . GLU C 2 5   ? 163.493 150.021 132.431 1.00 145.76 ? 5   GLU C OE2 1 
ATOM 1809 N N   . LEU C 2 6   ? 158.845 146.154 135.445 1.00 126.78 ? 6   LEU C N   1 
ATOM 1810 C CA  . LEU C 2 6   ? 157.636 145.818 136.186 1.00 118.52 ? 6   LEU C CA  1 
ATOM 1811 C C   . LEU C 2 6   ? 157.664 146.520 137.537 1.00 117.30 ? 6   LEU C C   1 
ATOM 1812 O O   . LEU C 2 6   ? 158.620 146.366 138.304 1.00 121.52 ? 6   LEU C O   1 
ATOM 1813 C CB  . LEU C 2 6   ? 157.509 144.308 136.369 1.00 114.47 ? 6   LEU C CB  1 
ATOM 1814 C CG  . LEU C 2 6   ? 157.370 143.482 135.092 1.00 114.74 ? 6   LEU C CG  1 
ATOM 1815 C CD1 . LEU C 2 6   ? 157.125 142.025 135.435 1.00 112.92 ? 6   LEU C CD1 1 
ATOM 1816 C CD2 . LEU C 2 6   ? 156.252 144.030 134.229 1.00 112.77 ? 6   LEU C CD2 1 
ATOM 1817 N N   . SER C 2 7   ? 156.621 147.283 137.823 1.00 112.45 ? 7   SER C N   1 
ATOM 1818 C CA  . SER C 2 7   ? 156.493 148.040 139.056 1.00 112.69 ? 7   SER C CA  1 
ATOM 1819 C C   . SER C 2 7   ? 155.067 147.903 139.558 1.00 111.32 ? 7   SER C C   1 
ATOM 1820 O O   . SER C 2 7   ? 154.169 147.532 138.795 1.00 110.61 ? 7   SER C O   1 
ATOM 1821 C CB  . SER C 2 7   ? 156.839 149.520 138.842 1.00 109.44 ? 7   SER C CB  1 
ATOM 1822 O OG  . SER C 2 7   ? 155.966 150.111 137.897 1.00 108.58 ? 7   SER C OG  1 
ATOM 1823 N N   . PRO C 2 8   ? 154.830 148.169 140.841 1.00 111.95 ? 8   PRO C N   1 
ATOM 1824 C CA  . PRO C 2 8   ? 153.448 148.208 141.330 1.00 110.57 ? 8   PRO C CA  1 
ATOM 1825 C C   . PRO C 2 8   ? 152.630 149.228 140.554 1.00 110.23 ? 8   PRO C C   1 
ATOM 1826 O O   . PRO C 2 8   ? 153.108 150.315 140.224 1.00 111.15 ? 8   PRO C O   1 
ATOM 1827 C CB  . PRO C 2 8   ? 153.604 148.607 142.800 1.00 113.03 ? 8   PRO C CB  1 
ATOM 1828 C CG  . PRO C 2 8   ? 154.963 148.125 143.169 1.00 114.41 ? 8   PRO C CG  1 
ATOM 1829 C CD  . PRO C 2 8   ? 155.806 148.295 141.937 1.00 114.62 ? 8   PRO C CD  1 
ATOM 1830 N N   . ILE C 2 9   ? 151.391 148.865 140.260 1.00 108.59 ? 9   ILE C N   1 
ATOM 1831 C CA  . ILE C 2 9   ? 150.537 149.680 139.412 1.00 104.62 ? 9   ILE C CA  1 
ATOM 1832 C C   . ILE C 2 9   ? 149.774 150.684 140.266 1.00 105.55 ? 9   ILE C C   1 
ATOM 1833 O O   . ILE C 2 9   ? 149.598 150.511 141.474 1.00 107.78 ? 9   ILE C O   1 
ATOM 1834 C CB  . ILE C 2 9   ? 149.573 148.807 138.591 1.00 102.45 ? 9   ILE C CB  1 
ATOM 1835 C CG1 . ILE C 2 9   ? 148.661 148.010 139.520 1.00 100.22 ? 9   ILE C CG1 1 
ATOM 1836 C CG2 . ILE C 2 9   ? 150.349 147.874 137.686 1.00 99.71  ? 9   ILE C CG2 1 
ATOM 1837 C CD1 . ILE C 2 9   ? 147.787 147.017 138.799 1.00 95.72  ? 9   ILE C CD1 1 
ATOM 1838 N N   . ASN C 2 10  ? 149.313 151.748 139.621 1.00 105.30 ? 10  ASN C N   1 
ATOM 1839 C CA  . ASN C 2 10  ? 148.523 152.794 140.251 1.00 106.62 ? 10  ASN C CA  1 
ATOM 1840 C C   . ASN C 2 10  ? 147.239 153.006 139.456 1.00 106.29 ? 10  ASN C C   1 
ATOM 1841 O O   . ASN C 2 10  ? 146.910 152.242 138.546 1.00 104.41 ? 10  ASN C O   1 
ATOM 1842 C CB  . ASN C 2 10  ? 149.322 154.096 140.355 1.00 106.37 ? 10  ASN C CB  1 
ATOM 1843 C CG  . ASN C 2 10  ? 149.623 154.703 139.000 1.00 106.88 ? 10  ASN C CG  1 
ATOM 1844 O OD1 . ASN C 2 10  ? 149.697 153.998 137.993 1.00 105.35 ? 10  ASN C OD1 1 
ATOM 1845 N ND2 . ASN C 2 10  ? 149.801 156.019 138.967 1.00 107.29 ? 10  ASN C ND2 1 
ATOM 1846 N N   . ALA C 2 11  ? 146.509 154.064 139.812 1.00 105.65 ? 11  ALA C N   1 
ATOM 1847 C CA  . ALA C 2 11  ? 145.280 154.384 139.096 1.00 104.76 ? 11  ALA C CA  1 
ATOM 1848 C C   . ALA C 2 11  ? 145.551 154.738 137.640 1.00 101.90 ? 11  ALA C C   1 
ATOM 1849 O O   . ALA C 2 11  ? 144.660 154.607 136.794 1.00 96.84  ? 11  ALA C O   1 
ATOM 1850 C CB  . ALA C 2 11  ? 144.549 155.530 139.793 1.00 103.19 ? 11  ALA C CB  1 
ATOM 1851 N N   . SER C 2 12  ? 146.767 155.190 137.329 1.00 102.66 ? 12  SER C N   1 
ATOM 1852 C CA  . SER C 2 12  ? 147.092 155.566 135.959 1.00 102.92 ? 12  SER C CA  1 
ATOM 1853 C C   . SER C 2 12  ? 147.263 154.359 135.046 1.00 101.21 ? 12  SER C C   1 
ATOM 1854 O O   . SER C 2 12  ? 147.188 154.510 133.823 1.00 98.71  ? 12  SER C O   1 
ATOM 1855 C CB  . SER C 2 12  ? 148.363 156.414 135.936 1.00 105.26 ? 12  SER C CB  1 
ATOM 1856 O OG  . SER C 2 12  ? 148.223 157.562 136.755 1.00 109.79 ? 12  SER C OG  1 
ATOM 1857 N N   . HIS C 2 13  ? 147.492 153.177 135.604 1.00 100.15 ? 13  HIS C N   1 
ATOM 1858 C CA  . HIS C 2 13  ? 147.715 152.001 134.777 1.00 94.38  ? 13  HIS C CA  1 
ATOM 1859 C C   . HIS C 2 13  ? 146.437 151.647 134.025 1.00 92.28  ? 13  HIS C C   1 
ATOM 1860 O O   . HIS C 2 13  ? 145.352 151.650 134.621 1.00 97.15  ? 13  HIS C O   1 
ATOM 1861 C CB  . HIS C 2 13  ? 148.168 150.821 135.630 1.00 96.99  ? 13  HIS C CB  1 
ATOM 1862 C CG  . HIS C 2 13  ? 148.704 149.674 134.834 1.00 95.51  ? 13  HIS C CG  1 
ATOM 1863 N ND1 . HIS C 2 13  ? 149.828 149.780 134.044 1.00 97.58  ? 13  HIS C ND1 1 
ATOM 1864 C CD2 . HIS C 2 13  ? 148.272 148.399 134.703 1.00 92.17  ? 13  HIS C CD2 1 
ATOM 1865 C CE1 . HIS C 2 13  ? 150.065 148.618 133.463 1.00 98.11  ? 13  HIS C CE1 1 
ATOM 1866 N NE2 . HIS C 2 13  ? 149.135 147.763 133.846 1.00 93.14  ? 13  HIS C NE2 1 
ATOM 1867 N N   . PRO C 2 14  ? 146.517 151.344 132.728 1.00 88.18  ? 14  PRO C N   1 
ATOM 1868 C CA  . PRO C 2 14  ? 145.297 151.093 131.948 1.00 89.75  ? 14  PRO C CA  1 
ATOM 1869 C C   . PRO C 2 14  ? 144.508 149.881 132.399 1.00 86.83  ? 14  PRO C C   1 
ATOM 1870 O O   . PRO C 2 14  ? 143.312 149.804 132.098 1.00 88.24  ? 14  PRO C O   1 
ATOM 1871 C CB  . PRO C 2 14  ? 145.826 150.903 130.521 1.00 88.88  ? 14  PRO C CB  1 
ATOM 1872 C CG  . PRO C 2 14  ? 147.175 151.536 130.526 1.00 93.02  ? 14  PRO C CG  1 
ATOM 1873 C CD  . PRO C 2 14  ? 147.721 151.303 131.892 1.00 89.26  ? 14  PRO C CD  1 
ATOM 1874 N N   . VAL C 2 15  ? 145.121 148.935 133.099 1.00 82.84  ? 15  VAL C N   1 
ATOM 1875 C CA  . VAL C 2 15  ? 144.435 147.725 133.526 1.00 82.12  ? 15  VAL C CA  1 
ATOM 1876 C C   . VAL C 2 15  ? 144.476 147.649 135.043 1.00 86.89  ? 15  VAL C C   1 
ATOM 1877 O O   . VAL C 2 15  ? 145.552 147.714 135.645 1.00 91.16  ? 15  VAL C O   1 
ATOM 1878 C CB  . VAL C 2 15  ? 145.061 146.462 132.908 1.00 78.11  ? 15  VAL C CB  1 
ATOM 1879 C CG1 . VAL C 2 15  ? 144.390 145.221 133.455 1.00 75.87  ? 15  VAL C CG1 1 
ATOM 1880 C CG2 . VAL C 2 15  ? 144.945 146.503 131.402 1.00 77.92  ? 15  VAL C CG2 1 
ATOM 1881 N N   . GLN C 2 16  ? 143.308 147.515 135.656 1.00 80.84  ? 16  GLN C N   1 
ATOM 1882 C CA  . GLN C 2 16  ? 143.197 147.203 137.069 1.00 73.92  ? 16  GLN C CA  1 
ATOM 1883 C C   . GLN C 2 16  ? 142.758 145.754 137.207 1.00 70.07  ? 16  GLN C C   1 
ATOM 1884 O O   . GLN C 2 16  ? 142.066 145.212 136.344 1.00 70.08  ? 16  GLN C O   1 
ATOM 1885 C CB  . GLN C 2 16  ? 142.212 148.135 137.776 1.00 76.56  ? 16  GLN C CB  1 
ATOM 1886 C CG  . GLN C 2 16  ? 142.646 149.586 137.799 1.00 85.34  ? 16  GLN C CG  1 
ATOM 1887 C CD  . GLN C 2 16  ? 143.840 149.825 138.701 1.00 95.73  ? 16  GLN C CD  1 
ATOM 1888 O OE1 . GLN C 2 16  ? 144.192 148.979 139.522 1.00 96.61  ? 16  GLN C OE1 1 
ATOM 1889 N NE2 . GLN C 2 16  ? 144.469 150.986 138.555 1.00 99.60  ? 16  GLN C NE2 1 
ATOM 1890 N N   . ALA C 2 17  ? 143.159 145.133 138.308 1.00 64.71  ? 17  ALA C N   1 
ATOM 1891 C CA  . ALA C 2 17  ? 143.019 143.691 138.441 1.00 64.40  ? 17  ALA C CA  1 
ATOM 1892 C C   . ALA C 2 17  ? 142.116 143.326 139.605 1.00 65.25  ? 17  ALA C C   1 
ATOM 1893 O O   . ALA C 2 17  ? 142.473 142.476 140.425 1.00 68.32  ? 17  ALA C O   1 
ATOM 1894 C CB  . ALA C 2 17  ? 144.388 143.037 138.614 1.00 64.92  ? 17  ALA C CB  1 
ATOM 1895 N N   . LEU C 2 18  ? 140.959 143.974 139.695 1.00 59.77  ? 18  LEU C N   1 
ATOM 1896 C CA  . LEU C 2 18  ? 140.021 143.715 140.775 1.00 60.71  ? 18  LEU C CA  1 
ATOM 1897 C C   . LEU C 2 18  ? 139.687 142.229 140.866 1.00 60.19  ? 18  LEU C C   1 
ATOM 1898 O O   . LEU C 2 18  ? 139.833 141.470 139.908 1.00 62.41  ? 18  LEU C O   1 
ATOM 1899 C CB  . LEU C 2 18  ? 138.736 144.510 140.562 1.00 65.41  ? 18  LEU C CB  1 
ATOM 1900 C CG  . LEU C 2 18  ? 138.872 145.894 139.928 1.00 69.65  ? 18  LEU C CG  1 
ATOM 1901 C CD1 . LEU C 2 18  ? 137.501 146.477 139.672 1.00 67.33  ? 18  LEU C CD1 1 
ATOM 1902 C CD2 . LEU C 2 18  ? 139.689 146.827 140.803 1.00 79.64  ? 18  LEU C CD2 1 
ATOM 1903 N N   . MET C 2 19  ? 139.239 141.816 142.047 1.00 63.81  ? 19  MET C N   1 
ATOM 1904 C CA  . MET C 2 19  ? 138.727 140.472 142.267 1.00 65.69  ? 19  MET C CA  1 
ATOM 1905 C C   . MET C 2 19  ? 137.296 140.564 142.766 1.00 70.97  ? 19  MET C C   1 
ATOM 1906 O O   . MET C 2 19  ? 137.022 141.254 143.753 1.00 76.06  ? 19  MET C O   1 
ATOM 1907 C CB  . MET C 2 19  ? 139.584 139.699 143.266 1.00 66.40  ? 19  MET C CB  1 
ATOM 1908 C CG  . MET C 2 19  ? 139.028 138.326 143.588 1.00 68.79  ? 19  MET C CG  1 
ATOM 1909 S SD  . MET C 2 19  ? 140.305 137.083 143.845 1.00 101.01 ? 19  MET C SD  1 
ATOM 1910 C CE  . MET C 2 19  ? 139.332 135.581 143.784 1.00 83.08  ? 19  MET C CE  1 
ATOM 1911 N N   . GLU C 2 20  ? 136.392 139.869 142.087 1.00 68.90  ? 20  GLU C N   1 
ATOM 1912 C CA  . GLU C 2 20  ? 134.972 139.875 142.405 1.00 69.61  ? 20  GLU C CA  1 
ATOM 1913 C C   . GLU C 2 20  ? 134.646 138.611 143.187 1.00 70.44  ? 20  GLU C C   1 
ATOM 1914 O O   . GLU C 2 20  ? 134.789 137.501 142.663 1.00 70.89  ? 20  GLU C O   1 
ATOM 1915 C CB  . GLU C 2 20  ? 134.138 139.958 141.127 1.00 70.65  ? 20  GLU C CB  1 
ATOM 1916 C CG  . GLU C 2 20  ? 132.691 139.528 141.275 1.00 74.74  ? 20  GLU C CG  1 
ATOM 1917 C CD  . GLU C 2 20  ? 131.985 139.412 139.937 1.00 88.23  ? 20  GLU C CD  1 
ATOM 1918 O OE1 . GLU C 2 20  ? 132.525 139.922 138.934 1.00 87.47  ? 20  GLU C OE1 1 
ATOM 1919 O OE2 . GLU C 2 20  ? 130.895 138.806 139.887 1.00 92.65  ? 20  GLU C OE2 1 
ATOM 1920 N N   . SER C 2 21  ? 134.213 138.777 144.432 1.00 69.94  ? 21  SER C N   1 
ATOM 1921 C CA  . SER C 2 21  ? 133.942 137.648 145.309 1.00 67.27  ? 21  SER C CA  1 
ATOM 1922 C C   . SER C 2 21  ? 132.585 137.817 145.970 1.00 68.55  ? 21  SER C C   1 
ATOM 1923 O O   . SER C 2 21  ? 132.116 138.941 146.163 1.00 72.58  ? 21  SER C O   1 
ATOM 1924 C CB  . SER C 2 21  ? 135.016 137.505 146.384 1.00 65.56  ? 21  SER C CB  1 
ATOM 1925 O OG  . SER C 2 21  ? 134.941 138.568 147.314 1.00 67.57  ? 21  SER C OG  1 
ATOM 1926 N N   . PHE C 2 22  ? 131.964 136.693 146.316 1.00 65.25  ? 22  PHE C N   1 
ATOM 1927 C CA  . PHE C 2 22  ? 130.682 136.667 147.007 1.00 59.12  ? 22  PHE C CA  1 
ATOM 1928 C C   . PHE C 2 22  ? 130.895 136.097 148.400 1.00 61.56  ? 22  PHE C C   1 
ATOM 1929 O O   . PHE C 2 22  ? 131.461 135.010 148.545 1.00 65.75  ? 22  PHE C O   1 
ATOM 1930 C CB  . PHE C 2 22  ? 129.665 135.833 146.234 1.00 56.57  ? 22  PHE C CB  1 
ATOM 1931 C CG  . PHE C 2 22  ? 129.419 136.322 144.840 1.00 58.61  ? 22  PHE C CG  1 
ATOM 1932 C CD1 . PHE C 2 22  ? 130.076 135.755 143.770 1.00 60.83  ? 22  PHE C CD1 1 
ATOM 1933 C CD2 . PHE C 2 22  ? 128.529 137.348 144.601 1.00 61.46  ? 22  PHE C CD2 1 
ATOM 1934 C CE1 . PHE C 2 22  ? 129.850 136.204 142.492 1.00 65.66  ? 22  PHE C CE1 1 
ATOM 1935 C CE2 . PHE C 2 22  ? 128.300 137.799 143.328 1.00 64.57  ? 22  PHE C CE2 1 
ATOM 1936 C CZ  . PHE C 2 22  ? 128.960 137.228 142.271 1.00 67.82  ? 22  PHE C CZ  1 
ATOM 1937 N N   . THR C 2 23  ? 130.449 136.826 149.420 1.00 58.65  ? 23  THR C N   1 
ATOM 1938 C CA  . THR C 2 23  ? 130.720 136.432 150.795 1.00 62.84  ? 23  THR C CA  1 
ATOM 1939 C C   . THR C 2 23  ? 129.642 137.001 151.704 1.00 64.22  ? 23  THR C C   1 
ATOM 1940 O O   . THR C 2 23  ? 129.079 138.062 151.430 1.00 68.34  ? 23  THR C O   1 
ATOM 1941 C CB  . THR C 2 23  ? 132.102 136.919 151.256 1.00 64.66  ? 23  THR C CB  1 
ATOM 1942 O OG1 . THR C 2 23  ? 133.089 136.580 150.276 1.00 76.68  ? 23  THR C OG1 1 
ATOM 1943 C CG2 . THR C 2 23  ? 132.492 136.280 152.578 1.00 60.82  ? 23  THR C CG2 1 
ATOM 1944 N N   . VAL C 2 24  ? 129.360 136.281 152.787 1.00 63.90  ? 24  VAL C N   1 
ATOM 1945 C CA  . VAL C 2 24  ? 128.547 136.779 153.888 1.00 59.17  ? 24  VAL C CA  1 
ATOM 1946 C C   . VAL C 2 24  ? 129.332 136.592 155.177 1.00 61.32  ? 24  VAL C C   1 
ATOM 1947 O O   . VAL C 2 24  ? 130.007 135.572 155.360 1.00 64.78  ? 24  VAL C O   1 
ATOM 1948 C CB  . VAL C 2 24  ? 127.181 136.069 153.975 1.00 54.02  ? 24  VAL C CB  1 
ATOM 1949 C CG1 . VAL C 2 24  ? 126.338 136.414 152.780 1.00 55.33  ? 24  VAL C CG1 1 
ATOM 1950 C CG2 . VAL C 2 24  ? 127.361 134.571 154.076 1.00 55.26  ? 24  VAL C CG2 1 
ATOM 1951 N N   . LEU C 2 25  ? 129.266 137.589 156.061 1.00 60.14  ? 25  LEU C N   1 
ATOM 1952 C CA  . LEU C 2 25  ? 129.997 137.500 157.321 1.00 61.51  ? 25  LEU C CA  1 
ATOM 1953 C C   . LEU C 2 25  ? 129.488 136.345 158.169 1.00 64.50  ? 25  LEU C C   1 
ATOM 1954 O O   . LEU C 2 25  ? 130.281 135.605 158.761 1.00 72.64  ? 25  LEU C O   1 
ATOM 1955 C CB  . LEU C 2 25  ? 129.898 138.817 158.085 1.00 66.88  ? 25  LEU C CB  1 
ATOM 1956 C CG  . LEU C 2 25  ? 131.023 139.826 157.842 1.00 73.38  ? 25  LEU C CG  1 
ATOM 1957 C CD1 . LEU C 2 25  ? 131.194 140.110 156.363 1.00 71.31  ? 25  LEU C CD1 1 
ATOM 1958 C CD2 . LEU C 2 25  ? 130.767 141.116 158.603 1.00 73.26  ? 25  LEU C CD2 1 
ATOM 1959 N N   . SER C 2 26  ? 128.173 136.172 158.240 1.00 60.92  ? 26  SER C N   1 
ATOM 1960 C CA  . SER C 2 26  ? 127.589 135.018 158.914 1.00 62.57  ? 26  SER C CA  1 
ATOM 1961 C C   . SER C 2 26  ? 126.157 134.879 158.428 1.00 60.08  ? 26  SER C C   1 
ATOM 1962 O O   . SER C 2 26  ? 125.629 135.762 157.756 1.00 66.29  ? 26  SER C O   1 
ATOM 1963 C CB  . SER C 2 26  ? 127.645 135.159 160.436 1.00 66.58  ? 26  SER C CB  1 
ATOM 1964 O OG  . SER C 2 26  ? 126.941 136.307 160.869 1.00 71.47  ? 26  SER C OG  1 
ATOM 1965 N N   . GLY C 2 27  ? 125.528 133.765 158.767 1.00 56.29  ? 27  GLY C N   1 
ATOM 1966 C CA  . GLY C 2 27  ? 124.144 133.610 158.369 1.00 58.71  ? 27  GLY C CA  1 
ATOM 1967 C C   . GLY C 2 27  ? 123.606 132.246 158.720 1.00 61.65  ? 27  GLY C C   1 
ATOM 1968 O O   . GLY C 2 27  ? 124.311 131.384 159.252 1.00 70.50  ? 27  GLY C O   1 
ATOM 1969 N N   . CYS C 2 28  ? 122.324 132.072 158.412 1.00 61.61  ? 28  CYS C N   1 
ATOM 1970 C CA  . CYS C 2 28  ? 121.618 130.818 158.621 1.00 65.69  ? 28  CYS C CA  1 
ATOM 1971 C C   . CYS C 2 28  ? 120.342 130.804 157.796 1.00 68.41  ? 28  CYS C C   1 
ATOM 1972 O O   . CYS C 2 28  ? 119.600 131.787 157.774 1.00 75.46  ? 28  CYS C O   1 
ATOM 1973 C CB  . CYS C 2 28  ? 121.294 130.618 160.102 1.00 79.28  ? 28  CYS C CB  1 
ATOM 1974 S SG  . CYS C 2 28  ? 120.253 131.908 160.830 1.00 93.21  ? 28  CYS C SG  1 
ATOM 1975 N N   . ALA C 2 29  ? 120.071 129.704 157.114 1.00 67.43  ? 29  ALA C N   1 
ATOM 1976 C CA  . ALA C 2 29  ? 118.833 129.545 156.374 1.00 73.44  ? 29  ALA C CA  1 
ATOM 1977 C C   . ALA C 2 29  ? 118.001 128.458 157.031 1.00 84.04  ? 29  ALA C C   1 
ATOM 1978 O O   . ALA C 2 29  ? 118.503 127.367 157.315 1.00 93.39  ? 29  ALA C O   1 
ATOM 1979 C CB  . ALA C 2 29  ? 119.102 129.195 154.913 1.00 73.60  ? 29  ALA C CB  1 
ATOM 1980 N N   . SER C 2 30  ? 116.735 128.760 157.281 1.00 84.03  ? 30  SER C N   1 
ATOM 1981 C CA  . SER C 2 30  ? 115.855 127.846 157.986 1.00 89.57  ? 30  SER C CA  1 
ATOM 1982 C C   . SER C 2 30  ? 114.648 127.524 157.124 1.00 98.83  ? 30  SER C C   1 
ATOM 1983 O O   . SER C 2 30  ? 114.083 128.407 156.475 1.00 103.58 ? 30  SER C O   1 
ATOM 1984 C CB  . SER C 2 30  ? 115.397 128.434 159.320 1.00 95.05  ? 30  SER C CB  1 
ATOM 1985 O OG  . SER C 2 30  ? 114.465 127.579 159.957 1.00 106.42 ? 30  SER C OG  1 
ATOM 1986 N N   . ARG C 2 31  ? 114.261 126.254 157.121 1.00 105.08 ? 31  ARG C N   1 
ATOM 1987 C CA  . ARG C 2 31  ? 113.071 125.799 156.419 1.00 110.68 ? 31  ARG C CA  1 
ATOM 1988 C C   . ARG C 2 31  ? 111.815 125.913 157.268 1.00 109.78 ? 31  ARG C C   1 
ATOM 1989 O O   . ARG C 2 31  ? 110.730 125.557 156.797 1.00 109.77 ? 31  ARG C O   1 
ATOM 1990 C CB  . ARG C 2 31  ? 113.250 124.348 155.968 1.00 112.20 ? 31  ARG C CB  1 
ATOM 1991 C CG  . ARG C 2 31  ? 113.504 123.385 157.113 1.00 110.92 ? 31  ARG C CG  1 
ATOM 1992 C CD  . ARG C 2 31  ? 113.603 121.950 156.629 1.00 114.31 ? 31  ARG C CD  1 
ATOM 1993 N NE  . ARG C 2 31  ? 113.875 121.026 157.724 1.00 114.52 ? 31  ARG C NE  1 
ATOM 1994 C CZ  . ARG C 2 31  ? 112.942 120.461 158.477 1.00 117.55 ? 31  ARG C CZ  1 
ATOM 1995 N NH1 . ARG C 2 31  ? 111.656 120.704 158.283 1.00 120.49 ? 31  ARG C NH1 1 
ATOM 1996 N NH2 . ARG C 2 31  ? 113.308 119.631 159.449 1.00 116.74 ? 31  ARG C NH2 1 
ATOM 1997 N N   . GLY C 2 32  ? 111.932 126.406 158.497 1.00 107.06 ? 32  GLY C N   1 
ATOM 1998 C CA  . GLY C 2 32  ? 110.821 126.410 159.426 1.00 108.56 ? 32  GLY C CA  1 
ATOM 1999 C C   . GLY C 2 32  ? 109.789 127.488 159.175 1.00 116.16 ? 32  GLY C C   1 
ATOM 2000 O O   . GLY C 2 32  ? 109.075 127.892 160.096 1.00 120.79 ? 32  GLY C O   1 
ATOM 2001 N N   . THR C 2 33  ? 109.695 127.964 157.936 1.00 116.76 ? 33  THR C N   1 
ATOM 2002 C CA  . THR C 2 33  ? 108.695 128.953 157.570 1.00 115.99 ? 33  THR C CA  1 
ATOM 2003 C C   . THR C 2 33  ? 107.733 128.452 156.503 1.00 118.57 ? 33  THR C C   1 
ATOM 2004 O O   . THR C 2 33  ? 106.911 129.236 156.013 1.00 119.92 ? 33  THR C O   1 
ATOM 2005 C CB  . THR C 2 33  ? 109.372 130.241 157.092 1.00 110.26 ? 33  THR C CB  1 
ATOM 2006 O OG1 . THR C 2 33  ? 110.168 130.776 158.154 1.00 109.87 ? 33  THR C OG1 1 
ATOM 2007 C CG2 . THR C 2 33  ? 108.333 131.272 156.704 1.00 103.65 ? 33  THR C CG2 1 
ATOM 2008 N N   . THR C 2 34  ? 107.814 127.176 156.124 1.00 118.54 ? 34  THR C N   1 
ATOM 2009 C CA  . THR C 2 34  ? 106.844 126.626 155.184 1.00 121.13 ? 34  THR C CA  1 
ATOM 2010 C C   . THR C 2 34  ? 105.440 126.649 155.772 1.00 125.00 ? 34  THR C C   1 
ATOM 2011 O O   . THR C 2 34  ? 104.476 127.012 155.087 1.00 122.27 ? 34  THR C O   1 
ATOM 2012 C CB  . THR C 2 34  ? 107.238 125.202 154.796 1.00 121.00 ? 34  THR C CB  1 
ATOM 2013 O OG1 . THR C 2 34  ? 107.319 124.391 155.975 1.00 121.20 ? 34  THR C OG1 1 
ATOM 2014 C CG2 . THR C 2 34  ? 108.585 125.197 154.092 1.00 118.92 ? 34  THR C CG2 1 
ATOM 2015 N N   . GLY C 2 35  ? 105.304 126.265 157.041 1.00 124.85 ? 35  GLY C N   1 
ATOM 2016 C CA  . GLY C 2 35  ? 104.004 126.325 157.686 1.00 122.23 ? 35  GLY C CA  1 
ATOM 2017 C C   . GLY C 2 35  ? 103.517 127.746 157.890 1.00 119.40 ? 35  GLY C C   1 
ATOM 2018 O O   . GLY C 2 35  ? 102.327 128.033 157.735 1.00 121.71 ? 35  GLY C O   1 
ATOM 2019 N N   . LEU C 2 36  ? 104.424 128.652 158.242 1.00 116.91 ? 36  LEU C N   1 
ATOM 2020 C CA  . LEU C 2 36  ? 104.041 130.028 158.501 1.00 116.34 ? 36  LEU C CA  1 
ATOM 2021 C C   . LEU C 2 36  ? 103.588 130.709 157.210 1.00 118.62 ? 36  LEU C C   1 
ATOM 2022 O O   . LEU C 2 36  ? 104.097 130.409 156.128 1.00 117.67 ? 36  LEU C O   1 
ATOM 2023 C CB  . LEU C 2 36  ? 105.204 130.795 159.120 1.00 116.03 ? 36  LEU C CB  1 
ATOM 2024 C CG  . LEU C 2 36  ? 105.626 130.301 160.504 1.00 115.03 ? 36  LEU C CG  1 
ATOM 2025 C CD1 . LEU C 2 36  ? 106.847 131.051 160.999 1.00 110.54 ? 36  LEU C CD1 1 
ATOM 2026 C CD2 . LEU C 2 36  ? 104.478 130.444 161.487 1.00 114.12 ? 36  LEU C CD2 1 
ATOM 2027 N N   . PRO C 2 37  ? 102.622 131.628 157.299 1.00 118.08 ? 37  PRO C N   1 
ATOM 2028 C CA  . PRO C 2 37  ? 102.079 132.239 156.078 1.00 119.93 ? 37  PRO C CA  1 
ATOM 2029 C C   . PRO C 2 37  ? 103.053 133.153 155.357 1.00 120.65 ? 37  PRO C C   1 
ATOM 2030 O O   . PRO C 2 37  ? 102.918 133.329 154.140 1.00 119.82 ? 37  PRO C O   1 
ATOM 2031 C CB  . PRO C 2 37  ? 100.865 133.022 156.591 1.00 115.52 ? 37  PRO C CB  1 
ATOM 2032 C CG  . PRO C 2 37  ? 101.217 133.351 158.001 1.00 113.90 ? 37  PRO C CG  1 
ATOM 2033 C CD  . PRO C 2 37  ? 101.989 132.167 158.515 1.00 113.29 ? 37  PRO C CD  1 
ATOM 2034 N N   . ARG C 2 38  ? 104.022 133.739 156.055 1.00 120.22 ? 38  ARG C N   1 
ATOM 2035 C CA  . ARG C 2 38  ? 104.914 134.728 155.468 1.00 115.81 ? 38  ARG C CA  1 
ATOM 2036 C C   . ARG C 2 38  ? 106.362 134.327 155.698 1.00 115.12 ? 38  ARG C C   1 
ATOM 2037 O O   . ARG C 2 38  ? 106.753 134.012 156.824 1.00 119.48 ? 38  ARG C O   1 
ATOM 2038 C CB  . ARG C 2 38  ? 104.665 136.115 156.067 1.00 114.43 ? 38  ARG C CB  1 
ATOM 2039 C CG  . ARG C 2 38  ? 103.200 136.510 156.126 1.00 115.73 ? 38  ARG C CG  1 
ATOM 2040 C CD  . ARG C 2 38  ? 102.996 137.738 156.996 1.00 116.52 ? 38  ARG C CD  1 
ATOM 2041 N NE  . ARG C 2 38  ? 101.584 138.073 157.140 1.00 130.48 ? 38  ARG C NE  1 
ATOM 2042 C CZ  . ARG C 2 38  ? 100.775 137.535 158.041 1.00 136.77 ? 38  ARG C CZ  1 
ATOM 2043 N NH1 . ARG C 2 38  ? 101.203 136.620 158.896 1.00 133.46 ? 38  ARG C NH1 1 
ATOM 2044 N NH2 . ARG C 2 38  ? 99.503  137.923 158.086 1.00 140.86 ? 38  ARG C NH2 1 
ATOM 2045 N N   . GLU C 2 39  ? 107.154 134.347 154.630 1.00 107.30 ? 39  GLU C N   1 
ATOM 2046 C CA  . GLU C 2 39  ? 108.587 134.132 154.752 1.00 98.80  ? 39  GLU C CA  1 
ATOM 2047 C C   . GLU C 2 39  ? 109.250 135.344 155.392 1.00 95.63  ? 39  GLU C C   1 
ATOM 2048 O O   . GLU C 2 39  ? 108.764 136.474 155.284 1.00 100.71 ? 39  GLU C O   1 
ATOM 2049 C CB  . GLU C 2 39  ? 109.219 133.866 153.388 1.00 91.31  ? 39  GLU C CB  1 
ATOM 2050 C CG  . GLU C 2 39  ? 109.091 132.442 152.895 1.00 99.82  ? 39  GLU C CG  1 
ATOM 2051 C CD  . GLU C 2 39  ? 109.820 132.223 151.585 1.00 103.16 ? 39  GLU C CD  1 
ATOM 2052 O OE1 . GLU C 2 39  ? 109.807 133.138 150.736 1.00 102.31 ? 39  GLU C OE1 1 
ATOM 2053 O OE2 . GLU C 2 39  ? 110.418 131.143 151.406 1.00 103.41 ? 39  GLU C OE2 1 
ATOM 2054 N N   . VAL C 2 40  ? 110.371 135.103 156.065 1.00 86.73  ? 40  VAL C N   1 
ATOM 2055 C CA  . VAL C 2 40  ? 111.119 136.158 156.735 1.00 82.37  ? 40  VAL C CA  1 
ATOM 2056 C C   . VAL C 2 40  ? 112.562 136.097 156.266 1.00 76.60  ? 40  VAL C C   1 
ATOM 2057 O O   . VAL C 2 40  ? 113.253 135.096 156.494 1.00 80.86  ? 40  VAL C O   1 
ATOM 2058 C CB  . VAL C 2 40  ? 111.048 136.035 158.264 1.00 85.71  ? 40  VAL C CB  1 
ATOM 2059 C CG1 . VAL C 2 40  ? 111.730 137.221 158.915 1.00 82.49  ? 40  VAL C CG1 1 
ATOM 2060 C CG2 . VAL C 2 40  ? 109.608 135.933 158.713 1.00 90.24  ? 40  VAL C CG2 1 
ATOM 2061 N N   . HIS C 2 41  ? 113.016 137.162 155.617 1.00 67.75  ? 41  HIS C N   1 
ATOM 2062 C CA  . HIS C 2 41  ? 114.405 137.314 155.214 1.00 60.64  ? 41  HIS C CA  1 
ATOM 2063 C C   . HIS C 2 41  ? 114.973 138.508 155.959 1.00 60.68  ? 41  HIS C C   1 
ATOM 2064 O O   . HIS C 2 41  ? 114.429 139.612 155.869 1.00 73.04  ? 41  HIS C O   1 
ATOM 2065 C CB  . HIS C 2 41  ? 114.523 137.511 153.703 1.00 61.01  ? 41  HIS C CB  1 
ATOM 2066 C CG  . HIS C 2 41  ? 114.089 136.324 152.907 1.00 65.55  ? 41  HIS C CG  1 
ATOM 2067 N ND1 . HIS C 2 41  ? 114.204 135.034 153.374 1.00 70.27  ? 41  HIS C ND1 1 
ATOM 2068 C CD2 . HIS C 2 41  ? 113.533 136.230 151.678 1.00 71.25  ? 41  HIS C CD2 1 
ATOM 2069 C CE1 . HIS C 2 41  ? 113.743 134.195 152.465 1.00 74.89  ? 41  HIS C CE1 1 
ATOM 2070 N NE2 . HIS C 2 41  ? 113.328 134.896 151.426 1.00 76.77  ? 41  HIS C NE2 1 
ATOM 2071 N N   . VAL C 2 42  ? 116.056 138.292 156.694 1.00 57.82  ? 42  VAL C N   1 
ATOM 2072 C CA  . VAL C 2 42  ? 116.658 139.321 157.527 1.00 54.47  ? 42  VAL C CA  1 
ATOM 2073 C C   . VAL C 2 42  ? 118.076 139.566 157.044 1.00 55.47  ? 42  VAL C C   1 
ATOM 2074 O O   . VAL C 2 42  ? 118.841 138.618 156.831 1.00 63.69  ? 42  VAL C O   1 
ATOM 2075 C CB  . VAL C 2 42  ? 116.648 138.922 159.011 1.00 58.10  ? 42  VAL C CB  1 
ATOM 2076 C CG1 . VAL C 2 42  ? 117.076 140.093 159.868 1.00 68.22  ? 42  VAL C CG1 1 
ATOM 2077 C CG2 . VAL C 2 42  ? 115.277 138.427 159.419 1.00 66.63  ? 42  VAL C CG2 1 
ATOM 2078 N N   . LEU C 2 43  ? 118.422 140.832 156.859 1.00 53.65  ? 43  LEU C N   1 
ATOM 2079 C CA  . LEU C 2 43  ? 119.773 141.230 156.499 1.00 55.61  ? 43  LEU C CA  1 
ATOM 2080 C C   . LEU C 2 43  ? 120.299 142.149 157.587 1.00 61.41  ? 43  LEU C C   1 
ATOM 2081 O O   . LEU C 2 43  ? 119.663 143.156 157.914 1.00 71.17  ? 43  LEU C O   1 
ATOM 2082 C CB  . LEU C 2 43  ? 119.812 141.936 155.143 1.00 51.62  ? 43  LEU C CB  1 
ATOM 2083 C CG  . LEU C 2 43  ? 119.527 141.137 153.875 1.00 48.26  ? 43  LEU C CG  1 
ATOM 2084 C CD1 . LEU C 2 43  ? 118.040 140.962 153.660 1.00 53.92  ? 43  LEU C CD1 1 
ATOM 2085 C CD2 . LEU C 2 43  ? 120.150 141.834 152.693 1.00 44.24  ? 43  LEU C CD2 1 
ATOM 2086 N N   . ASN C 2 44  ? 121.446 141.803 158.146 1.00 61.03  ? 44  ASN C N   1 
ATOM 2087 C CA  . ASN C 2 44  ? 122.140 142.650 159.104 1.00 66.34  ? 44  ASN C CA  1 
ATOM 2088 C C   . ASN C 2 44  ? 123.415 143.139 158.433 1.00 67.57  ? 44  ASN C C   1 
ATOM 2089 O O   . ASN C 2 44  ? 124.384 142.385 158.292 1.00 71.91  ? 44  ASN C O   1 
ATOM 2090 C CB  . ASN C 2 44  ? 122.438 141.890 160.393 1.00 74.79  ? 44  ASN C CB  1 
ATOM 2091 C CG  . ASN C 2 44  ? 122.853 142.805 161.523 1.00 77.36  ? 44  ASN C CG  1 
ATOM 2092 O OD1 . ASN C 2 44  ? 122.658 144.017 161.457 1.00 75.95  ? 44  ASN C OD1 1 
ATOM 2093 N ND2 . ASN C 2 44  ? 123.423 142.228 162.571 1.00 83.27  ? 44  ASN C ND2 1 
ATOM 2094 N N   . LEU C 2 45  ? 123.406 144.386 157.995 1.00 64.28  ? 45  LEU C N   1 
ATOM 2095 C CA  . LEU C 2 45  ? 124.549 144.948 157.302 1.00 68.92  ? 45  LEU C CA  1 
ATOM 2096 C C   . LEU C 2 45  ? 125.528 145.527 158.311 1.00 77.77  ? 45  LEU C C   1 
ATOM 2097 O O   . LEU C 2 45  ? 125.141 145.931 159.409 1.00 80.71  ? 45  LEU C O   1 
ATOM 2098 C CB  . LEU C 2 45  ? 124.106 146.019 156.303 1.00 65.75  ? 45  LEU C CB  1 
ATOM 2099 C CG  . LEU C 2 45  ? 123.574 145.515 154.956 1.00 60.22  ? 45  LEU C CG  1 
ATOM 2100 C CD1 . LEU C 2 45  ? 122.263 144.767 155.099 1.00 57.07  ? 45  LEU C CD1 1 
ATOM 2101 C CD2 . LEU C 2 45  ? 123.420 146.662 153.982 1.00 66.44  ? 45  LEU C CD2 1 
ATOM 2102 N N   . ARG C 2 46  ? 126.802 145.529 157.943 1.00 81.58  ? 46  ARG C N   1 
ATOM 2103 C CA  . ARG C 2 46  ? 127.867 146.066 158.777 1.00 83.69  ? 46  ARG C CA  1 
ATOM 2104 C C   . ARG C 2 46  ? 128.649 147.093 157.977 1.00 93.27  ? 46  ARG C C   1 
ATOM 2105 O O   . ARG C 2 46  ? 128.864 146.915 156.776 1.00 95.23  ? 46  ARG C O   1 
ATOM 2106 C CB  . ARG C 2 46  ? 128.806 144.964 159.267 1.00 79.82  ? 46  ARG C CB  1 
ATOM 2107 C CG  . ARG C 2 46  ? 128.132 143.891 160.086 1.00 79.78  ? 46  ARG C CG  1 
ATOM 2108 C CD  . ARG C 2 46  ? 127.399 144.485 161.265 1.00 79.30  ? 46  ARG C CD  1 
ATOM 2109 N NE  . ARG C 2 46  ? 127.017 143.459 162.224 1.00 85.02  ? 46  ARG C NE  1 
ATOM 2110 C CZ  . ARG C 2 46  ? 126.207 143.661 163.251 1.00 89.88  ? 46  ARG C CZ  1 
ATOM 2111 N NH1 . ARG C 2 46  ? 125.652 144.840 163.471 1.00 92.51  ? 46  ARG C NH1 1 
ATOM 2112 N NH2 . ARG C 2 46  ? 125.946 142.654 164.079 1.00 93.12  ? 46  ARG C NH2 1 
ATOM 2113 N N   . SER C 2 47  ? 129.065 148.162 158.638 1.00 102.20 ? 47  SER C N   1 
ATOM 2114 C CA  . SER C 2 47  ? 129.884 149.181 158.010 1.00 119.41 ? 47  SER C CA  1 
ATOM 2115 C C   . SER C 2 47  ? 131.312 149.094 158.542 1.00 130.88 ? 47  SER C C   1 
ATOM 2116 O O   . SER C 2 47  ? 131.641 148.266 159.394 1.00 128.94 ? 47  SER C O   1 
ATOM 2117 C CB  . SER C 2 47  ? 129.287 150.568 158.246 1.00 129.81 ? 47  SER C CB  1 
ATOM 2118 O OG  . SER C 2 47  ? 130.073 151.568 157.623 1.00 142.60 ? 47  SER C OG  1 
ATOM 2119 N N   . THR C 2 48  ? 132.171 149.964 158.022 1.00 142.32 ? 48  THR C N   1 
ATOM 2120 C CA  . THR C 2 48  ? 133.554 150.053 158.454 1.00 148.30 ? 48  THR C CA  1 
ATOM 2121 C C   . THR C 2 48  ? 133.762 151.329 159.265 1.00 154.83 ? 48  THR C C   1 
ATOM 2122 O O   . THR C 2 48  ? 132.824 152.070 159.566 1.00 153.38 ? 48  THR C O   1 
ATOM 2123 C CB  . THR C 2 48  ? 134.498 150.008 157.251 1.00 143.84 ? 48  THR C CB  1 
ATOM 2124 O OG1 . THR C 2 48  ? 134.141 151.039 156.322 1.00 146.96 ? 48  THR C OG1 1 
ATOM 2125 C CG2 . THR C 2 48  ? 134.415 148.660 156.561 1.00 129.60 ? 48  THR C CG2 1 
ATOM 2126 N N   . ASP C 2 49  ? 135.019 151.585 159.622 1.00 159.35 ? 49  ASP C N   1 
ATOM 2127 C CA  . ASP C 2 49  ? 135.378 152.783 160.369 1.00 161.69 ? 49  ASP C CA  1 
ATOM 2128 C C   . ASP C 2 49  ? 135.663 153.975 159.464 1.00 165.84 ? 49  ASP C C   1 
ATOM 2129 O O   . ASP C 2 49  ? 136.047 155.037 159.966 1.00 168.21 ? 49  ASP C O   1 
ATOM 2130 C CB  . ASP C 2 49  ? 136.594 152.502 161.257 1.00 159.53 ? 49  ASP C CB  1 
ATOM 2131 C CG  . ASP C 2 49  ? 136.666 153.425 162.458 1.00 160.52 ? 49  ASP C CG  1 
ATOM 2132 O OD1 . ASP C 2 49  ? 135.704 154.190 162.680 1.00 161.57 ? 49  ASP C OD1 1 
ATOM 2133 O OD2 . ASP C 2 49  ? 137.684 153.385 163.180 1.00 159.74 ? 49  ASP C OD2 1 
ATOM 2134 N N   . GLN C 2 50  ? 135.486 153.826 158.153 1.00 167.51 ? 50  GLN C N   1 
ATOM 2135 C CA  . GLN C 2 50  ? 135.738 154.915 157.225 1.00 168.28 ? 50  GLN C CA  1 
ATOM 2136 C C   . GLN C 2 50  ? 134.716 156.036 157.424 1.00 170.77 ? 50  GLN C C   1 
ATOM 2137 O O   . GLN C 2 50  ? 133.720 155.894 158.137 1.00 169.87 ? 50  GLN C O   1 
ATOM 2138 C CB  . GLN C 2 50  ? 135.691 154.409 155.784 1.00 163.68 ? 50  GLN C CB  1 
ATOM 2139 C CG  . GLN C 2 50  ? 136.548 153.179 155.523 1.00 162.08 ? 50  GLN C CG  1 
ATOM 2140 C CD  . GLN C 2 50  ? 138.035 153.470 155.591 1.00 162.30 ? 50  GLN C CD  1 
ATOM 2141 O OE1 . GLN C 2 50  ? 138.460 154.623 155.510 1.00 165.44 ? 50  GLN C OE1 1 
ATOM 2142 N NE2 . GLN C 2 50  ? 138.836 152.421 155.739 1.00 157.87 ? 50  GLN C NE2 1 
ATOM 2143 N N   . GLY C 2 51  ? 134.985 157.169 156.778 1.00 172.59 ? 51  GLY C N   1 
ATOM 2144 C CA  . GLY C 2 51  ? 134.115 158.319 156.845 1.00 173.17 ? 51  GLY C CA  1 
ATOM 2145 C C   . GLY C 2 51  ? 132.717 158.026 156.341 1.00 174.10 ? 51  GLY C C   1 
ATOM 2146 O O   . GLY C 2 51  ? 132.528 157.395 155.295 1.00 172.23 ? 51  GLY C O   1 
ATOM 2147 N N   . PRO C 2 52  ? 131.704 158.475 157.088 1.00 174.88 ? 52  PRO C N   1 
ATOM 2148 C CA  . PRO C 2 52  ? 130.316 158.220 156.664 1.00 173.58 ? 52  PRO C CA  1 
ATOM 2149 C C   . PRO C 2 52  ? 129.989 158.786 155.294 1.00 173.24 ? 52  PRO C C   1 
ATOM 2150 O O   . PRO C 2 52  ? 129.203 158.184 154.551 1.00 170.87 ? 52  PRO C O   1 
ATOM 2151 C CB  . PRO C 2 52  ? 129.486 158.890 157.769 1.00 168.73 ? 52  PRO C CB  1 
ATOM 2152 C CG  . PRO C 2 52  ? 130.404 158.970 158.947 1.00 166.65 ? 52  PRO C CG  1 
ATOM 2153 C CD  . PRO C 2 52  ? 131.771 159.186 158.376 1.00 169.86 ? 52  PRO C CD  1 
ATOM 2154 N N   . GLY C 2 53  ? 130.568 159.935 154.940 1.00 173.99 ? 53  GLY C N   1 
ATOM 2155 C CA  . GLY C 2 53  ? 130.333 160.492 153.618 1.00 172.78 ? 53  GLY C CA  1 
ATOM 2156 C C   . GLY C 2 53  ? 130.856 159.602 152.508 1.00 172.01 ? 53  GLY C C   1 
ATOM 2157 O O   . GLY C 2 53  ? 130.221 159.463 151.459 1.00 169.72 ? 53  GLY C O   1 
ATOM 2158 N N   . GLN C 2 54  ? 132.021 158.987 152.722 1.00 172.95 ? 54  GLN C N   1 
ATOM 2159 C CA  . GLN C 2 54  ? 132.585 158.090 151.722 1.00 174.41 ? 54  GLN C CA  1 
ATOM 2160 C C   . GLN C 2 54  ? 131.775 156.810 151.571 1.00 173.77 ? 54  GLN C C   1 
ATOM 2161 O O   . GLN C 2 54  ? 131.840 156.173 150.515 1.00 171.58 ? 54  GLN C O   1 
ATOM 2162 C CB  . GLN C 2 54  ? 134.033 157.747 152.079 1.00 171.49 ? 54  GLN C CB  1 
ATOM 2163 C CG  . GLN C 2 54  ? 134.952 158.953 152.178 1.00 168.64 ? 54  GLN C CG  1 
ATOM 2164 C CD  . GLN C 2 54  ? 135.147 159.653 150.846 1.00 169.60 ? 54  GLN C CD  1 
ATOM 2165 O OE1 . GLN C 2 54  ? 135.001 159.046 149.785 1.00 171.52 ? 54  GLN C OE1 1 
ATOM 2166 N NE2 . GLN C 2 54  ? 135.478 160.938 150.896 1.00 167.07 ? 54  GLN C NE2 1 
ATOM 2167 N N   . ARG C 2 55  ? 131.020 156.421 152.596 1.00 173.08 ? 55  ARG C N   1 
ATOM 2168 C CA  . ARG C 2 55  ? 130.209 155.215 152.514 1.00 167.53 ? 55  ARG C CA  1 
ATOM 2169 C C   . ARG C 2 55  ? 129.086 155.401 151.503 1.00 162.20 ? 55  ARG C C   1 
ATOM 2170 O O   . ARG C 2 55  ? 128.390 156.421 151.509 1.00 159.48 ? 55  ARG C O   1 
ATOM 2171 C CB  . ARG C 2 55  ? 129.633 154.874 153.888 1.00 165.08 ? 55  ARG C CB  1 
ATOM 2172 C CG  . ARG C 2 55  ? 130.680 154.734 154.979 1.00 168.84 ? 55  ARG C CG  1 
ATOM 2173 C CD  . ARG C 2 55  ? 130.034 154.558 156.343 1.00 167.31 ? 55  ARG C CD  1 
ATOM 2174 N NE  . ARG C 2 55  ? 131.025 154.491 157.411 1.00 168.62 ? 55  ARG C NE  1 
ATOM 2175 C CZ  . ARG C 2 55  ? 130.731 154.373 158.699 1.00 165.57 ? 55  ARG C CZ  1 
ATOM 2176 N NH1 . ARG C 2 55  ? 129.479 154.305 159.119 1.00 160.96 ? 55  ARG C NH1 1 
ATOM 2177 N NH2 . ARG C 2 55  ? 131.720 154.319 159.587 1.00 161.83 ? 55  ARG C NH2 1 
ATOM 2178 N N   . GLN C 2 56  ? 128.912 154.412 150.630 1.00 156.92 ? 56  GLN C N   1 
ATOM 2179 C CA  . GLN C 2 56  ? 127.854 154.481 149.633 1.00 147.69 ? 56  GLN C CA  1 
ATOM 2180 C C   . GLN C 2 56  ? 126.495 154.336 150.304 1.00 134.81 ? 56  GLN C C   1 
ATOM 2181 O O   . GLN C 2 56  ? 126.258 153.387 151.056 1.00 130.06 ? 56  GLN C O   1 
ATOM 2182 C CB  . GLN C 2 56  ? 128.045 153.396 148.575 1.00 142.19 ? 56  GLN C CB  1 
ATOM 2183 C CG  . GLN C 2 56  ? 129.349 153.508 147.802 1.00 141.15 ? 56  GLN C CG  1 
ATOM 2184 C CD  . GLN C 2 56  ? 129.396 152.583 146.601 1.00 135.90 ? 56  GLN C CD  1 
ATOM 2185 O OE1 . GLN C 2 56  ? 130.471 152.233 146.114 1.00 135.07 ? 56  GLN C OE1 1 
ATOM 2186 N NE2 . GLN C 2 56  ? 128.226 152.188 146.112 1.00 128.49 ? 56  GLN C NE2 1 
ATOM 2187 N N   . ARG C 2 57  ? 125.603 155.282 150.028 1.00 130.85 ? 57  ARG C N   1 
ATOM 2188 C CA  . ARG C 2 57  ? 124.279 155.291 150.633 1.00 130.24 ? 57  ARG C CA  1 
ATOM 2189 C C   . ARG C 2 57  ? 123.298 154.368 149.921 1.00 126.43 ? 57  ARG C C   1 
ATOM 2190 O O   . ARG C 2 57  ? 122.231 154.080 150.472 1.00 122.13 ? 57  ARG C O   1 
ATOM 2191 C CB  . ARG C 2 57  ? 123.733 156.722 150.653 1.00 130.89 ? 57  ARG C CB  1 
ATOM 2192 C CG  . ARG C 2 57  ? 122.541 156.936 151.572 1.00 124.35 ? 57  ARG C CG  1 
ATOM 2193 C CD  . ARG C 2 57  ? 122.115 158.395 151.612 1.00 130.22 ? 57  ARG C CD  1 
ATOM 2194 N NE  . ARG C 2 57  ? 123.121 159.248 152.234 1.00 134.90 ? 57  ARG C NE  1 
ATOM 2195 C CZ  . ARG C 2 57  ? 123.971 160.017 151.567 1.00 137.29 ? 57  ARG C CZ  1 
ATOM 2196 N NH1 . ARG C 2 57  ? 123.964 160.070 150.245 1.00 138.67 ? 57  ARG C NH1 1 
ATOM 2197 N NH2 . ARG C 2 57  ? 124.850 160.751 152.243 1.00 137.13 ? 57  ARG C NH2 1 
ATOM 2198 N N   . GLU C 2 58  ? 123.637 153.877 148.732 1.00 126.68 ? 58  GLU C N   1 
ATOM 2199 C CA  . GLU C 2 58  ? 122.718 153.107 147.908 1.00 118.29 ? 58  GLU C CA  1 
ATOM 2200 C C   . GLU C 2 58  ? 123.055 151.625 147.969 1.00 111.74 ? 58  GLU C C   1 
ATOM 2201 O O   . GLU C 2 58  ? 124.227 151.238 147.936 1.00 107.70 ? 58  GLU C O   1 
ATOM 2202 C CB  . GLU C 2 58  ? 122.744 153.591 146.453 1.00 119.45 ? 58  GLU C CB  1 
ATOM 2203 C CG  . GLU C 2 58  ? 124.128 153.613 145.818 1.00 128.01 ? 58  GLU C CG  1 
ATOM 2204 C CD  . GLU C 2 58  ? 124.109 154.122 144.388 1.00 132.60 ? 58  GLU C CD  1 
ATOM 2205 O OE1 . GLU C 2 58  ? 123.006 154.384 143.863 1.00 129.28 ? 58  GLU C OE1 1 
ATOM 2206 O OE2 . GLU C 2 58  ? 125.196 154.260 143.788 1.00 136.72 ? 58  GLU C OE2 1 
ATOM 2207 N N   . VAL C 2 59  ? 122.014 150.803 148.069 1.00 102.40 ? 59  VAL C N   1 
ATOM 2208 C CA  . VAL C 2 59  ? 122.118 149.353 148.004 1.00 88.88  ? 59  VAL C CA  1 
ATOM 2209 C C   . VAL C 2 59  ? 121.181 148.878 146.903 1.00 87.02  ? 59  VAL C C   1 
ATOM 2210 O O   . VAL C 2 59  ? 120.161 149.512 146.618 1.00 94.24  ? 59  VAL C O   1 
ATOM 2211 C CB  . VAL C 2 59  ? 121.772 148.692 149.354 1.00 84.63  ? 59  VAL C CB  1 
ATOM 2212 C CG1 . VAL C 2 59  ? 122.021 147.199 149.307 1.00 76.02  ? 59  VAL C CG1 1 
ATOM 2213 C CG2 . VAL C 2 59  ? 122.580 149.328 150.467 1.00 91.78  ? 59  VAL C CG2 1 
ATOM 2214 N N   . THR C 2 60  ? 121.529 147.758 146.281 1.00 74.23  ? 60  THR C N   1 
ATOM 2215 C CA  . THR C 2 60  ? 120.850 147.288 145.079 1.00 76.81  ? 60  THR C CA  1 
ATOM 2216 C C   . THR C 2 60  ? 120.342 145.871 145.277 1.00 67.97  ? 60  THR C C   1 
ATOM 2217 O O   . THR C 2 60  ? 120.637 144.963 144.500 1.00 70.08  ? 60  THR C O   1 
ATOM 2218 C CB  . THR C 2 60  ? 121.771 147.372 143.869 1.00 80.78  ? 60  THR C CB  1 
ATOM 2219 O OG1 . THR C 2 60  ? 122.562 148.563 143.958 1.00 83.04  ? 60  THR C OG1 1 
ATOM 2220 C CG2 . THR C 2 60  ? 120.957 147.420 142.585 1.00 80.92  ? 60  THR C CG2 1 
ATOM 2221 N N   . LEU C 2 61  ? 119.591 145.662 146.356 1.00 59.83  ? 61  LEU C N   1 
ATOM 2222 C CA  . LEU C 2 61  ? 119.039 144.354 146.684 1.00 59.49  ? 61  LEU C CA  1 
ATOM 2223 C C   . LEU C 2 61  ? 118.365 143.700 145.486 1.00 64.37  ? 61  LEU C C   1 
ATOM 2224 O O   . LEU C 2 61  ? 117.320 144.165 145.024 1.00 71.02  ? 61  LEU C O   1 
ATOM 2225 C CB  . LEU C 2 61  ? 118.037 144.494 147.829 1.00 60.20  ? 61  LEU C CB  1 
ATOM 2226 C CG  . LEU C 2 61  ? 117.352 143.240 148.360 1.00 55.58  ? 61  LEU C CG  1 
ATOM 2227 C CD1 . LEU C 2 61  ? 118.320 142.409 149.157 1.00 59.61  ? 61  LEU C CD1 1 
ATOM 2228 C CD2 . LEU C 2 61  ? 116.164 143.623 149.208 1.00 63.15  ? 61  LEU C CD2 1 
ATOM 2229 N N   . HIS C 2 62  ? 118.951 142.617 144.984 1.00 67.69  ? 62  HIS C N   1 
ATOM 2230 C CA  . HIS C 2 62  ? 118.370 141.836 143.903 1.00 66.17  ? 62  HIS C CA  1 
ATOM 2231 C C   . HIS C 2 62  ? 117.509 140.737 144.502 1.00 66.59  ? 62  HIS C C   1 
ATOM 2232 O O   . HIS C 2 62  ? 117.923 140.080 145.459 1.00 77.43  ? 62  HIS C O   1 
ATOM 2233 C CB  . HIS C 2 62  ? 119.456 141.209 143.026 1.00 61.09  ? 62  HIS C CB  1 
ATOM 2234 C CG  . HIS C 2 62  ? 120.252 142.194 142.231 1.00 66.69  ? 62  HIS C CG  1 
ATOM 2235 N ND1 . HIS C 2 62  ? 120.778 143.346 142.775 1.00 68.67  ? 62  HIS C ND1 1 
ATOM 2236 C CD2 . HIS C 2 62  ? 120.632 142.185 140.933 1.00 70.67  ? 62  HIS C CD2 1 
ATOM 2237 C CE1 . HIS C 2 62  ? 121.438 144.009 141.842 1.00 72.95  ? 62  HIS C CE1 1 
ATOM 2238 N NE2 . HIS C 2 62  ? 121.363 143.327 140.715 1.00 75.51  ? 62  HIS C NE2 1 
ATOM 2239 N N   . LEU C 2 63  ? 116.324 140.532 143.942 1.00 64.93  ? 63  LEU C N   1 
ATOM 2240 C CA  . LEU C 2 63  ? 115.436 139.457 144.360 1.00 67.22  ? 63  LEU C CA  1 
ATOM 2241 C C   . LEU C 2 63  ? 115.215 138.499 143.203 1.00 73.08  ? 63  LEU C C   1 
ATOM 2242 O O   . LEU C 2 63  ? 114.892 138.925 142.089 1.00 82.72  ? 63  LEU C O   1 
ATOM 2243 C CB  . LEU C 2 63  ? 114.091 139.993 144.845 1.00 74.94  ? 63  LEU C CB  1 
ATOM 2244 C CG  . LEU C 2 63  ? 113.989 140.432 146.301 1.00 76.11  ? 63  LEU C CG  1 
ATOM 2245 C CD1 . LEU C 2 63  ? 114.750 141.715 146.512 1.00 72.84  ? 63  LEU C CD1 1 
ATOM 2246 C CD2 . LEU C 2 63  ? 112.535 140.606 146.681 1.00 87.33  ? 63  LEU C CD2 1 
ATOM 2247 N N   . ASN C 2 64  ? 115.389 137.213 143.470 1.00 72.96  ? 64  ASN C N   1 
ATOM 2248 C CA  . ASN C 2 64  ? 115.130 136.178 142.484 1.00 76.00  ? 64  ASN C CA  1 
ATOM 2249 C C   . ASN C 2 64  ? 114.434 135.022 143.178 1.00 79.94  ? 64  ASN C C   1 
ATOM 2250 O O   . ASN C 2 64  ? 114.381 134.982 144.410 1.00 84.39  ? 64  ASN C O   1 
ATOM 2251 C CB  . ASN C 2 64  ? 116.424 135.685 141.820 1.00 76.65  ? 64  ASN C CB  1 
ATOM 2252 C CG  . ASN C 2 64  ? 116.974 136.672 140.817 1.00 76.10  ? 64  ASN C CG  1 
ATOM 2253 O OD1 . ASN C 2 64  ? 117.387 137.774 141.174 1.00 74.03  ? 64  ASN C OD1 1 
ATOM 2254 N ND2 . ASN C 2 64  ? 116.995 136.277 139.552 1.00 81.05  ? 64  ASN C ND2 1 
ATOM 2255 N N   . PRO C 2 65  ? 113.846 134.103 142.423 1.00 79.76  ? 65  PRO C N   1 
ATOM 2256 C CA  . PRO C 2 65  ? 113.423 132.835 143.019 1.00 86.42  ? 65  PRO C CA  1 
ATOM 2257 C C   . PRO C 2 65  ? 114.557 131.825 142.975 1.00 90.46  ? 65  PRO C C   1 
ATOM 2258 O O   . PRO C 2 65  ? 115.421 131.871 142.096 1.00 94.48  ? 65  PRO C O   1 
ATOM 2259 C CB  . PRO C 2 65  ? 112.257 132.404 142.128 1.00 98.84  ? 65  PRO C CB  1 
ATOM 2260 C CG  . PRO C 2 65  ? 112.628 132.946 140.794 1.00 100.01 ? 65  PRO C CG  1 
ATOM 2261 C CD  . PRO C 2 65  ? 113.352 134.250 141.045 1.00 90.18  ? 65  PRO C CD  1 
ATOM 2262 N N   . ILE C 2 66  ? 114.549 130.902 143.939 1.00 87.16  ? 66  ILE C N   1 
ATOM 2263 C CA  . ILE C 2 66  ? 115.588 129.884 143.980 1.00 83.42  ? 66  ILE C CA  1 
ATOM 2264 C C   . ILE C 2 66  ? 115.508 129.007 142.734 1.00 94.60  ? 66  ILE C C   1 
ATOM 2265 O O   . ILE C 2 66  ? 114.511 129.001 142.001 1.00 103.62 ? 66  ILE C O   1 
ATOM 2266 C CB  . ILE C 2 66  ? 115.486 129.036 145.256 1.00 81.69  ? 66  ILE C CB  1 
ATOM 2267 C CG1 . ILE C 2 66  ? 114.047 128.581 145.476 1.00 90.38  ? 66  ILE C CG1 1 
ATOM 2268 C CG2 . ILE C 2 66  ? 115.973 129.819 146.451 1.00 81.74  ? 66  ILE C CG2 1 
ATOM 2269 C CD1 . ILE C 2 66  ? 113.845 127.827 146.762 1.00 91.47  ? 66  ILE C CD1 1 
ATOM 2270 N N   . ALA C 2 67  ? 116.586 128.260 142.491 1.00 94.27  ? 67  ALA C N   1 
ATOM 2271 C CA  . ALA C 2 67  ? 116.694 127.473 141.268 1.00 96.32  ? 67  ALA C CA  1 
ATOM 2272 C C   . ALA C 2 67  ? 115.587 126.435 141.137 1.00 101.35 ? 67  ALA C C   1 
ATOM 2273 O O   . ALA C 2 67  ? 115.237 126.060 140.013 1.00 102.95 ? 67  ALA C O   1 
ATOM 2274 C CB  . ALA C 2 67  ? 118.059 126.789 141.209 1.00 92.19  ? 67  ALA C CB  1 
ATOM 2275 N N   . SER C 2 68  ? 115.025 125.968 142.247 1.00 102.98 ? 68  SER C N   1 
ATOM 2276 C CA  . SER C 2 68  ? 113.959 124.977 142.211 1.00 104.90 ? 68  SER C CA  1 
ATOM 2277 C C   . SER C 2 68  ? 112.572 125.597 142.120 1.00 105.32 ? 68  SER C C   1 
ATOM 2278 O O   . SER C 2 68  ? 111.580 124.865 142.182 1.00 107.49 ? 68  SER C O   1 
ATOM 2279 C CB  . SER C 2 68  ? 114.035 124.073 143.445 1.00 106.42 ? 68  SER C CB  1 
ATOM 2280 O OG  . SER C 2 68  ? 115.194 123.262 143.411 1.00 105.44 ? 68  SER C OG  1 
ATOM 2281 N N   . VAL C 2 69  ? 112.477 126.917 141.985 1.00 107.01 ? 69  VAL C N   1 
ATOM 2282 C CA  . VAL C 2 69  ? 111.199 127.613 141.908 1.00 111.84 ? 69  VAL C CA  1 
ATOM 2283 C C   . VAL C 2 69  ? 111.202 128.485 140.660 1.00 114.31 ? 69  VAL C C   1 
ATOM 2284 O O   . VAL C 2 69  ? 112.055 129.369 140.520 1.00 109.92 ? 69  VAL C O   1 
ATOM 2285 C CB  . VAL C 2 69  ? 110.935 128.464 143.160 1.00 107.34 ? 69  VAL C CB  1 
ATOM 2286 C CG1 . VAL C 2 69  ? 109.723 129.344 142.950 1.00 109.89 ? 69  VAL C CG1 1 
ATOM 2287 C CG2 . VAL C 2 69  ? 110.739 127.568 144.369 1.00 103.91 ? 69  VAL C CG2 1 
ATOM 2288 N N   . HIS C 2 70  ? 110.248 128.240 139.758 1.00 117.40 ? 70  HIS C N   1 
ATOM 2289 C CA  . HIS C 2 70  ? 110.154 129.058 138.553 1.00 121.88 ? 70  HIS C CA  1 
ATOM 2290 C C   . HIS C 2 70  ? 109.664 130.463 138.879 1.00 122.90 ? 70  HIS C C   1 
ATOM 2291 O O   . HIS C 2 70  ? 110.232 131.451 138.399 1.00 122.30 ? 70  HIS C O   1 
ATOM 2292 C CB  . HIS C 2 70  ? 109.232 128.393 137.533 1.00 123.96 ? 70  HIS C CB  1 
ATOM 2293 C CG  . HIS C 2 70  ? 109.211 129.079 136.203 1.00 129.95 ? 70  HIS C CG  1 
ATOM 2294 N ND1 . HIS C 2 70  ? 110.146 130.024 135.839 1.00 130.61 ? 70  HIS C ND1 1 
ATOM 2295 C CD2 . HIS C 2 70  ? 108.369 128.957 135.150 1.00 132.95 ? 70  HIS C CD2 1 
ATOM 2296 C CE1 . HIS C 2 70  ? 109.880 130.456 134.618 1.00 130.07 ? 70  HIS C CE1 1 
ATOM 2297 N NE2 . HIS C 2 70  ? 108.807 129.824 134.178 1.00 130.90 ? 70  HIS C NE2 1 
ATOM 2298 N N   . THR C 2 71  ? 108.609 130.572 139.683 1.00 123.45 ? 71  THR C N   1 
ATOM 2299 C CA  . THR C 2 71  ? 108.102 131.862 140.130 1.00 122.91 ? 71  THR C CA  1 
ATOM 2300 C C   . THR C 2 71  ? 107.625 131.726 141.567 1.00 122.26 ? 71  THR C C   1 
ATOM 2301 O O   . THR C 2 71  ? 107.005 130.721 141.927 1.00 123.46 ? 71  THR C O   1 
ATOM 2302 C CB  . THR C 2 71  ? 106.965 132.366 139.233 1.00 123.78 ? 71  THR C CB  1 
ATOM 2303 O OG1 . THR C 2 71  ? 106.367 133.527 139.826 1.00 120.49 ? 71  THR C OG1 1 
ATOM 2304 C CG2 . THR C 2 71  ? 105.907 131.289 139.041 1.00 125.87 ? 71  THR C CG2 1 
ATOM 2305 N N   . HIS C 2 72  ? 107.918 132.734 142.380 1.00 120.59 ? 72  HIS C N   1 
ATOM 2306 C CA  . HIS C 2 72  ? 107.656 132.694 143.811 1.00 121.38 ? 72  HIS C CA  1 
ATOM 2307 C C   . HIS C 2 72  ? 106.370 133.450 144.113 1.00 123.79 ? 72  HIS C C   1 
ATOM 2308 O O   . HIS C 2 72  ? 106.301 134.668 143.916 1.00 122.99 ? 72  HIS C O   1 
ATOM 2309 C CB  . HIS C 2 72  ? 108.830 133.294 144.582 1.00 117.75 ? 72  HIS C CB  1 
ATOM 2310 C CG  . HIS C 2 72  ? 108.623 133.341 146.063 1.00 113.70 ? 72  HIS C CG  1 
ATOM 2311 N ND1 . HIS C 2 72  ? 108.190 134.473 146.717 1.00 112.25 ? 72  HIS C ND1 1 
ATOM 2312 C CD2 . HIS C 2 72  ? 108.802 132.399 147.018 1.00 108.89 ? 72  HIS C CD2 1 
ATOM 2313 C CE1 . HIS C 2 72  ? 108.106 134.225 148.011 1.00 110.56 ? 72  HIS C CE1 1 
ATOM 2314 N NE2 . HIS C 2 72  ? 108.472 132.974 148.220 1.00 108.53 ? 72  HIS C NE2 1 
ATOM 2315 N N   . HIS C 2 73  ? 105.357 132.730 144.596 1.00 124.55 ? 73  HIS C N   1 
ATOM 2316 C CA  . HIS C 2 73  ? 104.074 133.316 144.983 1.00 123.58 ? 73  HIS C CA  1 
ATOM 2317 C C   . HIS C 2 73  ? 103.822 132.957 146.444 1.00 119.58 ? 73  HIS C C   1 
ATOM 2318 O O   . HIS C 2 73  ? 103.234 131.916 146.750 1.00 122.55 ? 73  HIS C O   1 
ATOM 2319 C CB  . HIS C 2 73  ? 102.945 132.841 144.068 1.00 124.78 ? 73  HIS C CB  1 
ATOM 2320 C CG  . HIS C 2 73  ? 102.740 131.357 144.071 1.00 127.71 ? 73  HIS C CG  1 
ATOM 2321 N ND1 . HIS C 2 73  ? 103.590 130.486 143.425 1.00 129.67 ? 73  HIS C ND1 1 
ATOM 2322 C CD2 . HIS C 2 73  ? 101.786 130.591 144.650 1.00 127.25 ? 73  HIS C CD2 1 
ATOM 2323 C CE1 . HIS C 2 73  ? 103.165 129.248 143.602 1.00 128.62 ? 73  HIS C CE1 1 
ATOM 2324 N NE2 . HIS C 2 73  ? 102.073 129.284 144.342 1.00 128.81 ? 73  HIS C NE2 1 
ATOM 2325 N N   . LYS C 2 74  ? 104.275 133.824 147.343 1.00 115.86 ? 74  LYS C N   1 
ATOM 2326 C CA  . LYS C 2 74  ? 104.094 133.662 148.779 1.00 113.69 ? 74  LYS C CA  1 
ATOM 2327 C C   . LYS C 2 74  ? 104.446 134.975 149.466 1.00 114.28 ? 74  LYS C C   1 
ATOM 2328 O O   . LYS C 2 74  ? 105.421 135.630 149.077 1.00 111.03 ? 74  LYS C O   1 
ATOM 2329 C CB  . LYS C 2 74  ? 104.958 132.518 149.313 1.00 110.74 ? 74  LYS C CB  1 
ATOM 2330 C CG  . LYS C 2 74  ? 104.781 132.246 150.795 1.00 109.83 ? 74  LYS C CG  1 
ATOM 2331 C CD  . LYS C 2 74  ? 105.498 130.977 151.221 1.00 107.76 ? 74  LYS C CD  1 
ATOM 2332 C CE  . LYS C 2 74  ? 105.234 130.666 152.686 1.00 112.91 ? 74  LYS C CE  1 
ATOM 2333 N NZ  . LYS C 2 74  ? 105.878 129.395 153.116 1.00 111.76 ? 74  LYS C NZ  1 
ATOM 2334 N N   . PRO C 2 75  ? 103.673 135.408 150.461 1.00 117.61 ? 75  PRO C N   1 
ATOM 2335 C CA  . PRO C 2 75  ? 104.006 136.655 151.158 1.00 113.81 ? 75  PRO C CA  1 
ATOM 2336 C C   . PRO C 2 75  ? 105.386 136.581 151.794 1.00 109.06 ? 75  PRO C C   1 
ATOM 2337 O O   . PRO C 2 75  ? 105.768 135.564 152.376 1.00 108.22 ? 75  PRO C O   1 
ATOM 2338 C CB  . PRO C 2 75  ? 102.903 136.776 152.214 1.00 110.89 ? 75  PRO C CB  1 
ATOM 2339 C CG  . PRO C 2 75  ? 101.762 135.996 151.653 1.00 108.91 ? 75  PRO C CG  1 
ATOM 2340 C CD  . PRO C 2 75  ? 102.384 134.852 150.906 1.00 114.47 ? 75  PRO C CD  1 
ATOM 2341 N N   . ILE C 2 76  ? 106.133 137.675 151.682 1.00 105.36 ? 76  ILE C N   1 
ATOM 2342 C CA  . ILE C 2 76  ? 107.502 137.746 152.173 1.00 98.19  ? 76  ILE C CA  1 
ATOM 2343 C C   . ILE C 2 76  ? 107.684 139.031 152.963 1.00 92.68  ? 76  ILE C C   1 
ATOM 2344 O O   . ILE C 2 76  ? 107.211 140.098 152.555 1.00 98.46  ? 76  ILE C O   1 
ATOM 2345 C CB  . ILE C 2 76  ? 108.528 137.666 151.025 1.00 95.03  ? 76  ILE C CB  1 
ATOM 2346 C CG1 . ILE C 2 76  ? 107.980 138.340 149.770 1.00 97.61  ? 76  ILE C CG1 1 
ATOM 2347 C CG2 . ILE C 2 76  ? 108.891 136.229 150.735 1.00 96.05  ? 76  ILE C CG2 1 
ATOM 2348 C CD1 . ILE C 2 76  ? 108.816 138.094 148.534 1.00 95.82  ? 76  ILE C CD1 1 
ATOM 2349 N N   . VAL C 2 77  ? 108.367 138.921 154.098 1.00 86.45  ? 77  VAL C N   1 
ATOM 2350 C CA  . VAL C 2 77  ? 108.717 140.057 154.938 1.00 82.88  ? 77  VAL C CA  1 
ATOM 2351 C C   . VAL C 2 77  ? 110.234 140.146 154.983 1.00 78.45  ? 77  VAL C C   1 
ATOM 2352 O O   . VAL C 2 77  ? 110.902 139.204 155.425 1.00 80.20  ? 77  VAL C O   1 
ATOM 2353 C CB  . VAL C 2 77  ? 108.136 139.922 156.352 1.00 87.40  ? 77  VAL C CB  1 
ATOM 2354 C CG1 . VAL C 2 77  ? 108.626 141.055 157.233 1.00 90.49  ? 77  VAL C CG1 1 
ATOM 2355 C CG2 . VAL C 2 77  ? 106.620 139.898 156.298 1.00 96.12  ? 77  VAL C CG2 1 
ATOM 2356 N N   . PHE C 2 78  ? 110.774 141.272 154.535 1.00 73.40  ? 78  PHE C N   1 
ATOM 2357 C CA  . PHE C 2 78  ? 112.212 141.488 154.475 1.00 68.62  ? 78  PHE C CA  1 
ATOM 2358 C C   . PHE C 2 78  ? 112.615 142.451 155.580 1.00 70.04  ? 78  PHE C C   1 
ATOM 2359 O O   . PHE C 2 78  ? 112.173 143.601 155.590 1.00 76.13  ? 78  PHE C O   1 
ATOM 2360 C CB  . PHE C 2 78  ? 112.624 142.043 153.112 1.00 69.65  ? 78  PHE C CB  1 
ATOM 2361 C CG  . PHE C 2 78  ? 112.503 141.057 151.992 1.00 71.04  ? 78  PHE C CG  1 
ATOM 2362 C CD1 . PHE C 2 78  ? 111.313 140.908 151.310 1.00 76.55  ? 78  PHE C CD1 1 
ATOM 2363 C CD2 . PHE C 2 78  ? 113.583 140.284 151.616 1.00 73.81  ? 78  PHE C CD2 1 
ATOM 2364 C CE1 . PHE C 2 78  ? 111.202 140.002 150.280 1.00 81.63  ? 78  PHE C CE1 1 
ATOM 2365 C CE2 . PHE C 2 78  ? 113.475 139.377 150.587 1.00 76.89  ? 78  PHE C CE2 1 
ATOM 2366 C CZ  . PHE C 2 78  ? 112.285 139.236 149.919 1.00 78.56  ? 78  PHE C CZ  1 
ATOM 2367 N N   . LEU C 2 79  ? 113.460 141.990 156.495 1.00 71.64  ? 79  LEU C N   1 
ATOM 2368 C CA  . LEU C 2 79  ? 113.987 142.823 157.574 1.00 66.02  ? 79  LEU C CA  1 
ATOM 2369 C C   . LEU C 2 79  ? 115.335 143.368 157.125 1.00 60.92  ? 79  LEU C C   1 
ATOM 2370 O O   . LEU C 2 79  ? 116.340 142.656 157.136 1.00 63.57  ? 79  LEU C O   1 
ATOM 2371 C CB  . LEU C 2 79  ? 114.119 142.031 158.869 1.00 67.41  ? 79  LEU C CB  1 
ATOM 2372 C CG  . LEU C 2 79  ? 112.885 141.829 159.745 1.00 78.79  ? 79  LEU C CG  1 
ATOM 2373 C CD1 . LEU C 2 79  ? 111.874 140.912 159.089 1.00 84.00  ? 79  LEU C CD1 1 
ATOM 2374 C CD2 . LEU C 2 79  ? 113.311 141.274 161.081 1.00 83.96  ? 79  LEU C CD2 1 
ATOM 2375 N N   . LEU C 2 80  ? 115.359 144.637 156.744 1.00 62.64  ? 80  LEU C N   1 
ATOM 2376 C CA  . LEU C 2 80  ? 116.558 145.270 156.198 1.00 64.36  ? 80  LEU C CA  1 
ATOM 2377 C C   . LEU C 2 80  ? 117.172 146.137 157.290 1.00 71.50  ? 80  LEU C C   1 
ATOM 2378 O O   . LEU C 2 80  ? 116.869 147.324 157.413 1.00 85.99  ? 80  LEU C O   1 
ATOM 2379 C CB  . LEU C 2 80  ? 116.222 146.082 154.955 1.00 67.98  ? 80  LEU C CB  1 
ATOM 2380 C CG  . LEU C 2 80  ? 116.227 145.379 153.599 1.00 62.47  ? 80  LEU C CG  1 
ATOM 2381 C CD1 . LEU C 2 80  ? 115.627 143.996 153.685 1.00 59.02  ? 80  LEU C CD1 1 
ATOM 2382 C CD2 . LEU C 2 80  ? 115.463 146.212 152.592 1.00 69.29  ? 80  LEU C CD2 1 
ATOM 2383 N N   . ASN C 2 81  ? 118.054 145.540 158.081 1.00 68.63  ? 81  ASN C N   1 
ATOM 2384 C CA  . ASN C 2 81  ? 118.657 146.212 159.222 1.00 76.35  ? 81  ASN C CA  1 
ATOM 2385 C C   . ASN C 2 81  ? 120.087 146.614 158.899 1.00 77.76  ? 81  ASN C C   1 
ATOM 2386 O O   . ASN C 2 81  ? 120.869 145.797 158.405 1.00 81.73  ? 81  ASN C O   1 
ATOM 2387 C CB  . ASN C 2 81  ? 118.631 145.313 160.457 1.00 79.16  ? 81  ASN C CB  1 
ATOM 2388 C CG  . ASN C 2 81  ? 119.491 145.848 161.579 1.00 87.18  ? 81  ASN C CG  1 
ATOM 2389 O OD1 . ASN C 2 81  ? 119.193 146.890 162.160 1.00 93.14  ? 81  ASN C OD1 1 
ATOM 2390 N ND2 . ASN C 2 81  ? 120.563 145.133 161.895 1.00 84.65  ? 81  ASN C ND2 1 
ATOM 2391 N N   . SER C 2 82  ? 120.426 147.871 159.184 1.00 78.41  ? 82  SER C N   1 
ATOM 2392 C CA  . SER C 2 82  ? 121.771 148.371 158.989 1.00 82.49  ? 82  SER C CA  1 
ATOM 2393 C C   . SER C 2 82  ? 121.987 149.542 159.933 1.00 95.56  ? 82  SER C C   1 
ATOM 2394 O O   . SER C 2 82  ? 121.064 150.346 160.128 1.00 102.94 ? 82  SER C O   1 
ATOM 2395 C CB  . SER C 2 82  ? 122.013 148.818 157.549 1.00 82.99  ? 82  SER C CB  1 
ATOM 2396 O OG  . SER C 2 82  ? 121.162 149.896 157.211 1.00 92.15  ? 82  SER C OG  1 
ATOM 2397 N N   . PRO C 2 83  ? 123.177 149.677 160.516 1.00 96.87  ? 83  PRO C N   1 
ATOM 2398 C CA  . PRO C 2 83  ? 123.418 150.782 161.454 1.00 103.24 ? 83  PRO C CA  1 
ATOM 2399 C C   . PRO C 2 83  ? 123.579 152.130 160.767 1.00 107.04 ? 83  PRO C C   1 
ATOM 2400 O O   . PRO C 2 83  ? 123.923 153.123 161.415 1.00 110.03 ? 83  PRO C O   1 
ATOM 2401 C CB  . PRO C 2 83  ? 124.710 150.358 162.162 1.00 100.03 ? 83  PRO C CB  1 
ATOM 2402 C CG  . PRO C 2 83  ? 125.404 149.490 161.173 1.00 96.04  ? 83  PRO C CG  1 
ATOM 2403 C CD  . PRO C 2 83  ? 124.324 148.758 160.436 1.00 89.45  ? 83  PRO C CD  1 
ATOM 2404 N N   . GLN C 2 84  ? 123.336 152.180 159.463 1.00 107.91 ? 84  GLN C N   1 
ATOM 2405 C CA  . GLN C 2 84  ? 123.439 153.406 158.692 1.00 116.82 ? 84  GLN C CA  1 
ATOM 2406 C C   . GLN C 2 84  ? 122.191 153.582 157.842 1.00 116.81 ? 84  GLN C C   1 
ATOM 2407 O O   . GLN C 2 84  ? 121.627 152.599 157.352 1.00 114.66 ? 84  GLN C O   1 
ATOM 2408 C CB  . GLN C 2 84  ? 124.684 153.376 157.790 1.00 116.80 ? 84  GLN C CB  1 
ATOM 2409 C CG  . GLN C 2 84  ? 124.957 154.658 157.014 1.00 121.50 ? 84  GLN C CG  1 
ATOM 2410 C CD  . GLN C 2 84  ? 125.457 155.785 157.897 1.00 125.55 ? 84  GLN C CD  1 
ATOM 2411 O OE1 . GLN C 2 84  ? 125.849 155.566 159.043 1.00 124.54 ? 84  GLN C OE1 1 
ATOM 2412 N NE2 . GLN C 2 84  ? 125.447 157.001 157.364 1.00 124.34 ? 84  GLN C NE2 1 
ATOM 2413 N N   . PRO C 2 85  ? 121.721 154.819 157.667 1.00 117.62 ? 85  PRO C N   1 
ATOM 2414 C CA  . PRO C 2 85  ? 120.602 155.055 156.743 1.00 115.83 ? 85  PRO C CA  1 
ATOM 2415 C C   . PRO C 2 85  ? 120.989 154.673 155.322 1.00 117.84 ? 85  PRO C C   1 
ATOM 2416 O O   . PRO C 2 85  ? 122.073 155.017 154.846 1.00 121.66 ? 85  PRO C O   1 
ATOM 2417 C CB  . PRO C 2 85  ? 120.342 156.559 156.876 1.00 115.82 ? 85  PRO C CB  1 
ATOM 2418 C CG  . PRO C 2 85  ? 120.856 156.906 158.230 1.00 115.43 ? 85  PRO C CG  1 
ATOM 2419 C CD  . PRO C 2 85  ? 122.052 156.024 158.446 1.00 115.88 ? 85  PRO C CD  1 
ATOM 2420 N N   . LEU C 2 86  ? 120.090 153.963 154.644 1.00 114.73 ? 86  LEU C N   1 
ATOM 2421 C CA  . LEU C 2 86  ? 120.355 153.433 153.316 1.00 111.59 ? 86  LEU C CA  1 
ATOM 2422 C C   . LEU C 2 86  ? 119.141 153.625 152.421 1.00 111.53 ? 86  LEU C C   1 
ATOM 2423 O O   . LEU C 2 86  ? 118.016 153.806 152.891 1.00 111.90 ? 86  LEU C O   1 
ATOM 2424 C CB  . LEU C 2 86  ? 120.713 151.942 153.362 1.00 105.01 ? 86  LEU C CB  1 
ATOM 2425 C CG  . LEU C 2 86  ? 121.959 151.526 154.138 1.00 101.78 ? 86  LEU C CG  1 
ATOM 2426 C CD1 . LEU C 2 86  ? 122.111 150.023 154.088 1.00 83.98  ? 86  LEU C CD1 1 
ATOM 2427 C CD2 . LEU C 2 86  ? 123.188 152.207 153.571 1.00 105.93 ? 86  LEU C CD2 1 
ATOM 2428 N N   . VAL C 2 87  ? 119.389 153.587 151.115 1.00 114.28 ? 87  VAL C N   1 
ATOM 2429 C CA  . VAL C 2 87  ? 118.336 153.513 150.110 1.00 114.66 ? 87  VAL C CA  1 
ATOM 2430 C C   . VAL C 2 87  ? 118.540 152.220 149.334 1.00 106.32 ? 87  VAL C C   1 
ATOM 2431 O O   . VAL C 2 87  ? 119.617 151.988 148.772 1.00 104.67 ? 87  VAL C O   1 
ATOM 2432 C CB  . VAL C 2 87  ? 118.334 154.735 149.177 1.00 117.66 ? 87  VAL C CB  1 
ATOM 2433 C CG1 . VAL C 2 87  ? 117.675 155.922 149.865 1.00 109.46 ? 87  VAL C CG1 1 
ATOM 2434 C CG2 . VAL C 2 87  ? 119.747 155.096 148.751 1.00 119.64 ? 87  VAL C CG2 1 
ATOM 2435 N N   . TRP C 2 88  ? 117.513 151.377 149.313 1.00 101.97 ? 88  TRP C N   1 
ATOM 2436 C CA  . TRP C 2 88  ? 117.601 150.040 148.739 1.00 94.00  ? 88  TRP C CA  1 
ATOM 2437 C C   . TRP C 2 88  ? 116.973 150.049 147.351 1.00 89.15  ? 88  TRP C C   1 
ATOM 2438 O O   . TRP C 2 88  ? 115.750 149.965 147.215 1.00 90.84  ? 88  TRP C O   1 
ATOM 2439 C CB  . TRP C 2 88  ? 116.907 149.025 149.643 1.00 91.29  ? 88  TRP C CB  1 
ATOM 2440 C CG  . TRP C 2 88  ? 117.616 148.780 150.935 1.00 87.45  ? 88  TRP C CG  1 
ATOM 2441 C CD1 . TRP C 2 88  ? 117.711 149.633 151.993 1.00 90.65  ? 88  TRP C CD1 1 
ATOM 2442 C CD2 . TRP C 2 88  ? 118.320 147.594 151.311 1.00 79.09  ? 88  TRP C CD2 1 
ATOM 2443 N NE1 . TRP C 2 88  ? 118.437 149.053 153.003 1.00 86.73  ? 88  TRP C NE1 1 
ATOM 2444 C CE2 . TRP C 2 88  ? 118.821 147.799 152.608 1.00 80.61  ? 88  TRP C CE2 1 
ATOM 2445 C CE3 . TRP C 2 88  ? 118.575 146.377 150.675 1.00 68.39  ? 88  TRP C CE3 1 
ATOM 2446 C CZ2 . TRP C 2 88  ? 119.563 146.834 153.279 1.00 75.65  ? 88  TRP C CZ2 1 
ATOM 2447 C CZ3 . TRP C 2 88  ? 119.309 145.425 151.341 1.00 63.95  ? 88  TRP C CZ3 1 
ATOM 2448 C CH2 . TRP C 2 88  ? 119.794 145.656 152.629 1.00 68.89  ? 88  TRP C CH2 1 
ATOM 2449 N N   . HIS C 2 89  ? 117.809 150.131 146.323 1.00 87.05  ? 89  HIS C N   1 
ATOM 2450 C CA  . HIS C 2 89  ? 117.339 150.119 144.941 1.00 89.72  ? 89  HIS C CA  1 
ATOM 2451 C C   . HIS C 2 89  ? 116.979 148.684 144.577 1.00 84.46  ? 89  HIS C C   1 
ATOM 2452 O O   . HIS C 2 89  ? 117.793 147.952 144.011 1.00 87.92  ? 89  HIS C O   1 
ATOM 2453 C CB  . HIS C 2 89  ? 118.401 150.687 144.009 1.00 91.87  ? 89  HIS C CB  1 
ATOM 2454 C CG  . HIS C 2 89  ? 118.739 152.119 144.282 1.00 104.03 ? 89  HIS C CG  1 
ATOM 2455 N ND1 . HIS C 2 89  ? 119.953 152.676 143.942 1.00 111.47 ? 89  HIS C ND1 1 
ATOM 2456 C CD2 . HIS C 2 89  ? 118.018 153.109 144.858 1.00 108.55 ? 89  HIS C CD2 1 
ATOM 2457 C CE1 . HIS C 2 89  ? 119.967 153.947 144.301 1.00 117.28 ? 89  HIS C CE1 1 
ATOM 2458 N NE2 . HIS C 2 89  ? 118.805 154.236 144.859 1.00 115.50 ? 89  HIS C NE2 1 
ATOM 2459 N N   . LEU C 2 90  ? 115.755 148.282 144.896 1.00 81.39  ? 90  LEU C N   1 
ATOM 2460 C CA  . LEU C 2 90  ? 115.324 146.915 144.645 1.00 81.59  ? 90  LEU C CA  1 
ATOM 2461 C C   . LEU C 2 90  ? 115.297 146.608 143.153 1.00 87.12  ? 90  LEU C C   1 
ATOM 2462 O O   . LEU C 2 90  ? 115.038 147.477 142.319 1.00 92.33  ? 90  LEU C O   1 
ATOM 2463 C CB  . LEU C 2 90  ? 113.938 146.672 145.233 1.00 85.91  ? 90  LEU C CB  1 
ATOM 2464 C CG  . LEU C 2 90  ? 113.852 146.099 146.642 1.00 81.31  ? 90  LEU C CG  1 
ATOM 2465 C CD1 . LEU C 2 90  ? 114.588 146.978 147.629 1.00 81.00  ? 90  LEU C CD1 1 
ATOM 2466 C CD2 . LEU C 2 90  ? 112.401 145.953 147.035 1.00 89.44  ? 90  LEU C CD2 1 
ATOM 2467 N N   . LYS C 2 91  ? 115.574 145.348 142.827 1.00 88.15  ? 91  LYS C N   1 
ATOM 2468 C CA  . LYS C 2 91  ? 115.466 144.849 141.458 1.00 87.70  ? 91  LYS C CA  1 
ATOM 2469 C C   . LYS C 2 91  ? 114.957 143.419 141.544 1.00 88.40  ? 91  LYS C C   1 
ATOM 2470 O O   . LYS C 2 91  ? 115.705 142.526 141.946 1.00 92.91  ? 91  LYS C O   1 
ATOM 2471 C CB  . LYS C 2 91  ? 116.807 144.905 140.734 1.00 81.38  ? 91  LYS C CB  1 
ATOM 2472 C CG  . LYS C 2 91  ? 117.316 146.301 140.433 1.00 82.69  ? 91  LYS C CG  1 
ATOM 2473 C CD  . LYS C 2 91  ? 118.630 146.234 139.680 1.00 80.18  ? 91  LYS C CD  1 
ATOM 2474 C CE  . LYS C 2 91  ? 118.512 145.332 138.461 1.00 75.33  ? 91  LYS C CE  1 
ATOM 2475 N NZ  . LYS C 2 91  ? 119.820 145.137 137.777 1.00 70.32  ? 91  LYS C NZ  1 
ATOM 2476 N N   . THR C 2 92  ? 113.702 143.198 141.181 1.00 87.43  ? 92  THR C N   1 
ATOM 2477 C CA  . THR C 2 92  ? 113.096 141.881 141.301 1.00 90.64  ? 92  THR C CA  1 
ATOM 2478 C C   . THR C 2 92  ? 113.035 141.193 139.945 1.00 91.64  ? 92  THR C C   1 
ATOM 2479 O O   . THR C 2 92  ? 112.940 141.842 138.902 1.00 97.52  ? 92  THR C O   1 
ATOM 2480 C CB  . THR C 2 92  ? 111.689 141.977 141.888 1.00 102.41 ? 92  THR C CB  1 
ATOM 2481 O OG1 . THR C 2 92  ? 110.836 142.668 140.969 1.00 111.29 ? 92  THR C OG1 1 
ATOM 2482 C CG2 . THR C 2 92  ? 111.717 142.729 143.206 1.00 101.15 ? 92  THR C CG2 1 
ATOM 2483 N N   . GLU C 2 93  ? 113.096 139.864 139.971 1.00 91.59  ? 93  GLU C N   1 
ATOM 2484 C CA  . GLU C 2 93  ? 113.006 139.082 138.746 1.00 96.71  ? 93  GLU C CA  1 
ATOM 2485 C C   . GLU C 2 93  ? 112.197 137.825 139.018 1.00 99.38  ? 93  GLU C C   1 
ATOM 2486 O O   . GLU C 2 93  ? 112.380 137.186 140.057 1.00 104.20 ? 93  GLU C O   1 
ATOM 2487 C CB  . GLU C 2 93  ? 114.399 138.714 138.227 1.00 97.15  ? 93  GLU C CB  1 
ATOM 2488 C CG  . GLU C 2 93  ? 114.398 137.894 136.950 1.00 103.67 ? 93  GLU C CG  1 
ATOM 2489 C CD  . GLU C 2 93  ? 114.253 138.748 135.707 1.00 111.20 ? 93  GLU C CD  1 
ATOM 2490 O OE1 . GLU C 2 93  ? 114.349 139.987 135.823 1.00 113.57 ? 93  GLU C OE1 1 
ATOM 2491 O OE2 . GLU C 2 93  ? 114.048 138.179 134.615 1.00 112.64 ? 93  GLU C OE2 1 
ATOM 2492 N N   . ARG C 2 94  ? 111.304 137.483 138.091 1.00 96.47  ? 94  ARG C N   1 
ATOM 2493 C CA  . ARG C 2 94  ? 110.528 136.244 138.149 1.00 101.87 ? 94  ARG C CA  1 
ATOM 2494 C C   . ARG C 2 94  ? 109.766 136.097 139.463 1.00 107.31 ? 94  ARG C C   1 
ATOM 2495 O O   . ARG C 2 94  ? 109.601 134.988 139.976 1.00 106.35 ? 94  ARG C O   1 
ATOM 2496 C CB  . ARG C 2 94  ? 111.418 135.020 137.911 1.00 104.22 ? 94  ARG C CB  1 
ATOM 2497 C CG  . ARG C 2 94  ? 111.858 134.856 136.465 1.00 102.52 ? 94  ARG C CG  1 
ATOM 2498 C CD  . ARG C 2 94  ? 112.721 133.620 136.274 1.00 109.87 ? 94  ARG C CD  1 
ATOM 2499 N NE  . ARG C 2 94  ? 113.992 133.725 136.979 1.00 115.18 ? 94  ARG C NE  1 
ATOM 2500 C CZ  . ARG C 2 94  ? 115.065 134.339 136.500 1.00 114.72 ? 94  ARG C CZ  1 
ATOM 2501 N NH1 . ARG C 2 94  ? 115.052 134.927 135.315 1.00 110.82 ? 94  ARG C NH1 1 
ATOM 2502 N NH2 . ARG C 2 94  ? 116.177 134.365 137.228 1.00 109.82 ? 94  ARG C NH2 1 
ATOM 2503 N N   . LEU C 2 95  ? 109.289 137.207 140.013 1.00 111.67 ? 95  LEU C N   1 
ATOM 2504 C CA  . LEU C 2 95  ? 108.454 137.191 141.204 1.00 118.19 ? 95  LEU C CA  1 
ATOM 2505 C C   . LEU C 2 95  ? 106.995 137.370 140.811 1.00 125.27 ? 95  LEU C C   1 
ATOM 2506 O O   . LEU C 2 95  ? 106.679 138.129 139.890 1.00 127.13 ? 95  LEU C O   1 
ATOM 2507 C CB  . LEU C 2 95  ? 108.872 138.288 142.185 1.00 115.54 ? 95  LEU C CB  1 
ATOM 2508 C CG  . LEU C 2 95  ? 110.121 138.005 143.020 1.00 111.26 ? 95  LEU C CG  1 
ATOM 2509 C CD1 . LEU C 2 95  ? 110.426 139.171 143.940 1.00 107.58 ? 95  LEU C CD1 1 
ATOM 2510 C CD2 . LEU C 2 95  ? 109.943 136.729 143.822 1.00 109.53 ? 95  LEU C CD2 1 
ATOM 2511 N N   . ALA C 2 96  ? 106.109 136.666 141.511 1.00 127.13 ? 96  ALA C N   1 
ATOM 2512 C CA  . ALA C 2 96  ? 104.690 136.734 141.200 1.00 131.23 ? 96  ALA C CA  1 
ATOM 2513 C C   . ALA C 2 96  ? 104.141 138.127 141.495 1.00 134.24 ? 96  ALA C C   1 
ATOM 2514 O O   . ALA C 2 96  ? 104.740 138.924 142.222 1.00 135.04 ? 96  ALA C O   1 
ATOM 2515 C CB  . ALA C 2 96  ? 103.913 135.684 141.993 1.00 129.83 ? 96  ALA C CB  1 
ATOM 2516 N N   . ALA C 2 97  ? 102.981 138.415 140.914 1.00 136.65 ? 97  ALA C N   1 
ATOM 2517 C CA  . ALA C 2 97  ? 102.350 139.721 141.015 1.00 137.68 ? 97  ALA C CA  1 
ATOM 2518 C C   . ALA C 2 97  ? 101.081 139.630 141.851 1.00 138.54 ? 97  ALA C C   1 
ATOM 2519 O O   . ALA C 2 97  ? 100.357 138.632 141.794 1.00 139.18 ? 97  ALA C O   1 
ATOM 2520 C CB  . ALA C 2 97  ? 102.021 140.279 139.629 1.00 137.33 ? 97  ALA C CB  1 
ATOM 2521 N N   . GLY C 2 98  ? 100.823 140.678 142.632 1.00 136.98 ? 98  GLY C N   1 
ATOM 2522 C CA  . GLY C 2 98  ? 99.627  140.766 143.439 1.00 134.41 ? 98  GLY C CA  1 
ATOM 2523 C C   . GLY C 2 98  ? 99.739  140.197 144.835 1.00 136.94 ? 98  GLY C C   1 
ATOM 2524 O O   . GLY C 2 98  ? 98.827  140.406 145.644 1.00 136.41 ? 98  GLY C O   1 
ATOM 2525 N N   . VAL C 2 99  ? 100.815 139.489 145.150 1.00 139.28 ? 99  VAL C N   1 
ATOM 2526 C CA  . VAL C 2 99  ? 100.988 138.977 146.514 1.00 134.78 ? 99  VAL C CA  1 
ATOM 2527 C C   . VAL C 2 99  ? 101.527 140.092 147.401 1.00 130.58 ? 99  VAL C C   1 
ATOM 2528 O O   . VAL C 2 99  ? 102.562 140.697 147.066 1.00 127.69 ? 99  VAL C O   1 
ATOM 2529 C CB  . VAL C 2 99  ? 101.926 137.769 146.513 1.00 128.28 ? 99  VAL C CB  1 
ATOM 2530 C CG1 . VAL C 2 99  ? 101.980 137.140 147.897 1.00 121.76 ? 99  VAL C CG1 1 
ATOM 2531 C CG2 . VAL C 2 99  ? 101.475 136.754 145.476 1.00 126.17 ? 99  VAL C CG2 1 
ATOM 2532 N N   . PRO C 2 100 ? 100.870 140.414 148.514 1.00 129.29 ? 100 PRO C N   1 
ATOM 2533 C CA  . PRO C 2 100 ? 101.378 141.482 149.383 1.00 128.49 ? 100 PRO C CA  1 
ATOM 2534 C C   . PRO C 2 100 ? 102.747 141.134 149.948 1.00 124.56 ? 100 PRO C C   1 
ATOM 2535 O O   . PRO C 2 100 ? 103.027 139.982 150.285 1.00 121.93 ? 100 PRO C O   1 
ATOM 2536 C CB  . PRO C 2 100 ? 100.318 141.574 150.486 1.00 127.06 ? 100 PRO C CB  1 
ATOM 2537 C CG  . PRO C 2 100 ? 99.684  140.223 150.506 1.00 124.89 ? 100 PRO C CG  1 
ATOM 2538 C CD  . PRO C 2 100 ? 99.675  139.765 149.076 1.00 126.78 ? 100 PRO C CD  1 
ATOM 2539 N N   . ARG C 2 101 ? 103.602 142.148 150.046 1.00 120.90 ? 101 ARG C N   1 
ATOM 2540 C CA  . ARG C 2 101 ? 104.959 141.983 150.545 1.00 110.82 ? 101 ARG C CA  1 
ATOM 2541 C C   . ARG C 2 101 ? 105.267 143.106 151.521 1.00 106.32 ? 101 ARG C C   1 
ATOM 2542 O O   . ARG C 2 101 ? 104.739 144.214 151.387 1.00 110.17 ? 101 ARG C O   1 
ATOM 2543 C CB  . ARG C 2 101 ? 105.978 141.979 149.399 1.00 108.31 ? 101 ARG C CB  1 
ATOM 2544 C CG  . ARG C 2 101 ? 105.739 140.890 148.366 1.00 111.59 ? 101 ARG C CG  1 
ATOM 2545 C CD  . ARG C 2 101 ? 106.845 140.864 147.334 1.00 115.43 ? 101 ARG C CD  1 
ATOM 2546 N NE  . ARG C 2 101 ? 106.718 139.747 146.406 1.00 122.78 ? 101 ARG C NE  1 
ATOM 2547 C CZ  . ARG C 2 101 ? 106.162 139.830 145.206 1.00 125.32 ? 101 ARG C CZ  1 
ATOM 2548 N NH1 . ARG C 2 101 ? 105.659 140.966 144.754 1.00 124.13 ? 101 ARG C NH1 1 
ATOM 2549 N NH2 . ARG C 2 101 ? 106.110 138.745 144.438 1.00 127.59 ? 101 ARG C NH2 1 
ATOM 2550 N N   . LEU C 2 102 ? 106.116 142.816 152.503 1.00 103.04 ? 102 LEU C N   1 
ATOM 2551 C CA  . LEU C 2 102 ? 106.441 143.760 153.562 1.00 100.72 ? 102 LEU C CA  1 
ATOM 2552 C C   . LEU C 2 102 ? 107.946 143.965 153.628 1.00 96.72  ? 102 LEU C C   1 
ATOM 2553 O O   . LEU C 2 102 ? 108.718 143.015 153.479 1.00 98.09  ? 102 LEU C O   1 
ATOM 2554 C CB  . LEU C 2 102 ? 105.918 143.264 154.914 1.00 97.65  ? 102 LEU C CB  1 
ATOM 2555 C CG  . LEU C 2 102 ? 106.229 144.097 156.157 1.00 98.40  ? 102 LEU C CG  1 
ATOM 2556 C CD1 . LEU C 2 102 ? 105.595 145.471 156.066 1.00 104.10 ? 102 LEU C CD1 1 
ATOM 2557 C CD2 . LEU C 2 102 ? 105.747 143.371 157.398 1.00 104.46 ? 102 LEU C CD2 1 
ATOM 2558 N N   . PHE C 2 103 ? 108.358 145.208 153.856 1.00 94.69  ? 103 PHE C N   1 
ATOM 2559 C CA  . PHE C 2 103 ? 109.771 145.558 153.978 1.00 90.17  ? 103 PHE C CA  1 
ATOM 2560 C C   . PHE C 2 103 ? 109.953 146.354 155.265 1.00 93.90  ? 103 PHE C C   1 
ATOM 2561 O O   . PHE C 2 103 ? 109.741 147.569 155.291 1.00 100.33 ? 103 PHE C O   1 
ATOM 2562 C CB  . PHE C 2 103 ? 110.249 146.338 152.759 1.00 87.68  ? 103 PHE C CB  1 
ATOM 2563 C CG  . PHE C 2 103 ? 110.342 145.506 151.518 1.00 87.24  ? 103 PHE C CG  1 
ATOM 2564 C CD1 . PHE C 2 103 ? 109.217 145.233 150.766 1.00 91.80  ? 103 PHE C CD1 1 
ATOM 2565 C CD2 . PHE C 2 103 ? 111.554 144.983 151.110 1.00 89.24  ? 103 PHE C CD2 1 
ATOM 2566 C CE1 . PHE C 2 103 ? 109.299 144.460 149.628 1.00 92.77  ? 103 PHE C CE1 1 
ATOM 2567 C CE2 . PHE C 2 103 ? 111.641 144.209 149.974 1.00 87.73  ? 103 PHE C CE2 1 
ATOM 2568 C CZ  . PHE C 2 103 ? 110.512 143.948 149.232 1.00 88.57  ? 103 PHE C CZ  1 
ATOM 2569 N N   . LEU C 2 104 ? 110.324 145.658 156.335 1.00 93.90  ? 104 LEU C N   1 
ATOM 2570 C CA  . LEU C 2 104 ? 110.635 146.288 157.614 1.00 94.97  ? 104 LEU C CA  1 
ATOM 2571 C C   . LEU C 2 104 ? 112.092 146.719 157.557 1.00 88.25  ? 104 LEU C C   1 
ATOM 2572 O O   . LEU C 2 104 ? 112.998 145.926 157.815 1.00 88.42  ? 104 LEU C O   1 
ATOM 2573 C CB  . LEU C 2 104 ? 110.386 145.324 158.766 1.00 95.19  ? 104 LEU C CB  1 
ATOM 2574 C CG  . LEU C 2 104 ? 109.001 144.694 158.852 1.00 105.81 ? 104 LEU C CG  1 
ATOM 2575 C CD1 . LEU C 2 104 ? 108.975 143.649 159.948 1.00 105.32 ? 104 LEU C CD1 1 
ATOM 2576 C CD2 . LEU C 2 104 ? 107.955 145.763 159.103 1.00 111.92 ? 104 LEU C CD2 1 
ATOM 2577 N N   . VAL C 2 105 ? 112.324 147.968 157.204 1.00 87.55  ? 105 VAL C N   1 
ATOM 2578 C CA  . VAL C 2 105 ? 113.671 148.479 157.066 1.00 87.86  ? 105 VAL C CA  1 
ATOM 2579 C C   . VAL C 2 105 ? 114.025 149.259 158.322 1.00 97.52  ? 105 VAL C C   1 
ATOM 2580 O O   . VAL C 2 105 ? 113.169 149.575 159.150 1.00 107.20 ? 105 VAL C O   1 
ATOM 2581 C CB  . VAL C 2 105 ? 113.821 149.350 155.804 1.00 90.66  ? 105 VAL C CB  1 
ATOM 2582 C CG1 . VAL C 2 105 ? 113.196 148.648 154.617 1.00 89.22  ? 105 VAL C CG1 1 
ATOM 2583 C CG2 . VAL C 2 105 ? 113.183 150.703 156.021 1.00 104.67 ? 105 VAL C CG2 1 
ATOM 2584 N N   . SER C 2 106 ? 115.311 149.552 158.480 1.00 93.64  ? 106 SER C N   1 
ATOM 2585 C CA  . SER C 2 106 ? 115.748 150.339 159.623 1.00 99.08  ? 106 SER C CA  1 
ATOM 2586 C C   . SER C 2 106 ? 115.252 151.775 159.499 1.00 112.19 ? 106 SER C C   1 
ATOM 2587 O O   . SER C 2 106 ? 114.920 152.248 158.409 1.00 113.72 ? 106 SER C O   1 
ATOM 2588 C CB  . SER C 2 106 ? 117.269 150.321 159.733 1.00 95.95  ? 106 SER C CB  1 
ATOM 2589 O OG  . SER C 2 106 ? 117.857 150.991 158.633 1.00 102.87 ? 106 SER C OG  1 
ATOM 2590 N N   . GLU C 2 107 ? 115.198 152.468 160.635 1.00 114.95 ? 107 GLU C N   1 
ATOM 2591 C CA  . GLU C 2 107 ? 114.723 153.846 160.652 1.00 118.60 ? 107 GLU C CA  1 
ATOM 2592 C C   . GLU C 2 107 ? 115.608 154.732 159.786 1.00 125.03 ? 107 GLU C C   1 
ATOM 2593 O O   . GLU C 2 107 ? 116.836 154.607 159.789 1.00 125.68 ? 107 GLU C O   1 
ATOM 2594 C CB  . GLU C 2 107 ? 114.690 154.380 162.085 1.00 124.82 ? 107 GLU C CB  1 
ATOM 2595 C CG  . GLU C 2 107 ? 114.219 155.824 162.200 1.00 136.88 ? 107 GLU C CG  1 
ATOM 2596 C CD  . GLU C 2 107 ? 114.256 156.343 163.625 1.00 142.67 ? 107 GLU C CD  1 
ATOM 2597 O OE1 . GLU C 2 107 ? 114.537 155.546 164.545 1.00 143.94 ? 107 GLU C OE1 1 
ATOM 2598 O OE2 . GLU C 2 107 ? 114.004 157.550 163.825 1.00 141.00 ? 107 GLU C OE2 1 
ATOM 2599 N N   . GLY C 2 108 ? 114.975 155.635 159.041 1.00 125.37 ? 108 GLY C N   1 
ATOM 2600 C CA  . GLY C 2 108 ? 115.706 156.514 158.152 1.00 125.44 ? 108 GLY C CA  1 
ATOM 2601 C C   . GLY C 2 108 ? 116.098 155.894 156.833 1.00 126.00 ? 108 GLY C C   1 
ATOM 2602 O O   . GLY C 2 108 ? 116.915 156.471 156.109 1.00 124.41 ? 108 GLY C O   1 
ATOM 2603 N N   . SER C 2 109 ? 115.540 154.735 156.496 1.00 126.12 ? 109 SER C N   1 
ATOM 2604 C CA  . SER C 2 109 ? 115.857 154.036 155.262 1.00 124.11 ? 109 SER C CA  1 
ATOM 2605 C C   . SER C 2 109 ? 114.634 153.997 154.357 1.00 122.08 ? 109 SER C C   1 
ATOM 2606 O O   . SER C 2 109 ? 113.510 153.770 154.812 1.00 121.71 ? 109 SER C O   1 
ATOM 2607 C CB  . SER C 2 109 ? 116.345 152.611 155.539 1.00 113.82 ? 109 SER C CB  1 
ATOM 2608 O OG  . SER C 2 109 ? 116.687 151.949 154.336 1.00 110.65 ? 109 SER C OG  1 
ATOM 2609 N N   . VAL C 2 110 ? 114.866 154.222 153.066 1.00 118.21 ? 110 VAL C N   1 
ATOM 2610 C CA  . VAL C 2 110 ? 113.806 154.266 152.071 1.00 117.23 ? 110 VAL C CA  1 
ATOM 2611 C C   . VAL C 2 110 ? 114.076 153.190 151.032 1.00 113.82 ? 110 VAL C C   1 
ATOM 2612 O O   . VAL C 2 110 ? 115.228 152.886 150.711 1.00 109.18 ? 110 VAL C O   1 
ATOM 2613 C CB  . VAL C 2 110 ? 113.702 155.655 151.403 1.00 117.16 ? 110 VAL C CB  1 
ATOM 2614 C CG1 . VAL C 2 110 ? 112.389 155.792 150.646 1.00 111.92 ? 110 VAL C CG1 1 
ATOM 2615 C CG2 . VAL C 2 110 ? 113.850 156.758 152.440 1.00 112.86 ? 110 VAL C CG2 1 
ATOM 2616 N N   . VAL C 2 111 ? 113.002 152.613 150.503 1.00 112.17 ? 111 VAL C N   1 
ATOM 2617 C CA  . VAL C 2 111 ? 113.084 151.539 149.522 1.00 107.25 ? 111 VAL C CA  1 
ATOM 2618 C C   . VAL C 2 111 ? 112.516 152.048 148.206 1.00 106.51 ? 111 VAL C C   1 
ATOM 2619 O O   . VAL C 2 111 ? 111.337 152.415 148.133 1.00 106.90 ? 111 VAL C O   1 
ATOM 2620 C CB  . VAL C 2 111 ? 112.334 150.285 149.990 1.00 107.86 ? 111 VAL C CB  1 
ATOM 2621 C CG1 . VAL C 2 111 ? 112.161 149.322 148.839 1.00 105.15 ? 111 VAL C CG1 1 
ATOM 2622 C CG2 . VAL C 2 111 ? 113.086 149.626 151.125 1.00 101.01 ? 111 VAL C CG2 1 
ATOM 2623 N N   . GLN C 2 112 ? 113.350 152.059 147.167 1.00 105.87 ? 112 GLN C N   1 
ATOM 2624 C CA  . GLN C 2 112 ? 112.943 152.513 145.839 1.00 108.08 ? 112 GLN C CA  1 
ATOM 2625 C C   . GLN C 2 112 ? 112.501 151.297 145.031 1.00 105.12 ? 112 GLN C C   1 
ATOM 2626 O O   . GLN C 2 112 ? 113.266 150.705 144.271 1.00 101.02 ? 112 GLN C O   1 
ATOM 2627 C CB  . GLN C 2 112 ? 114.078 153.269 145.155 1.00 106.10 ? 112 GLN C CB  1 
ATOM 2628 C CG  . GLN C 2 112 ? 114.358 154.638 145.747 1.00 110.11 ? 112 GLN C CG  1 
ATOM 2629 C CD  . GLN C 2 112 ? 113.226 155.623 145.507 1.00 116.19 ? 112 GLN C CD  1 
ATOM 2630 O OE1 . GLN C 2 112 ? 112.401 155.435 144.613 1.00 116.57 ? 112 GLN C OE1 1 
ATOM 2631 N NE2 . GLN C 2 112 ? 113.183 156.680 146.310 1.00 116.86 ? 112 GLN C NE2 1 
ATOM 2632 N N   . PHE C 2 113 ? 111.238 150.932 145.204 1.00 108.89 ? 113 PHE C N   1 
ATOM 2633 C CA  . PHE C 2 113 ? 110.686 149.793 144.489 1.00 111.33 ? 113 PHE C CA  1 
ATOM 2634 C C   . PHE C 2 113 ? 110.755 150.043 142.987 1.00 116.41 ? 113 PHE C C   1 
ATOM 2635 O O   . PHE C 2 113 ? 110.558 151.182 142.544 1.00 120.60 ? 113 PHE C O   1 
ATOM 2636 C CB  . PHE C 2 113 ? 109.235 149.544 144.896 1.00 115.42 ? 113 PHE C CB  1 
ATOM 2637 C CG  . PHE C 2 113 ? 109.016 149.478 146.377 1.00 117.75 ? 113 PHE C CG  1 
ATOM 2638 C CD1 . PHE C 2 113 ? 109.016 148.262 147.036 1.00 119.15 ? 113 PHE C CD1 1 
ATOM 2639 C CD2 . PHE C 2 113 ? 108.787 150.632 147.109 1.00 118.38 ? 113 PHE C CD2 1 
ATOM 2640 C CE1 . PHE C 2 113 ? 108.805 148.197 148.399 1.00 120.20 ? 113 PHE C CE1 1 
ATOM 2641 C CE2 . PHE C 2 113 ? 108.577 150.573 148.472 1.00 121.44 ? 113 PHE C CE2 1 
ATOM 2642 C CZ  . PHE C 2 113 ? 108.584 149.353 149.119 1.00 120.48 ? 113 PHE C CZ  1 
ATOM 2643 N N   . PRO C 2 114 ? 111.035 149.027 142.179 1.00 118.30 ? 114 PRO C N   1 
ATOM 2644 C CA  . PRO C 2 114 ? 110.975 149.201 140.726 1.00 126.47 ? 114 PRO C CA  1 
ATOM 2645 C C   . PRO C 2 114 ? 109.533 149.289 140.249 1.00 136.33 ? 114 PRO C C   1 
ATOM 2646 O O   . PRO C 2 114 ? 108.581 149.022 140.985 1.00 136.06 ? 114 PRO C O   1 
ATOM 2647 C CB  . PRO C 2 114 ? 111.671 147.948 140.193 1.00 120.15 ? 114 PRO C CB  1 
ATOM 2648 C CG  . PRO C 2 114 ? 111.421 146.924 141.248 1.00 114.01 ? 114 PRO C CG  1 
ATOM 2649 C CD  . PRO C 2 114 ? 111.441 147.664 142.557 1.00 114.22 ? 114 PRO C CD  1 
ATOM 2650 N N   . SER C 2 115 ? 109.380 149.678 138.987 1.00 139.82 ? 115 SER C N   1 
ATOM 2651 C CA  . SER C 2 115 ? 108.053 149.801 138.408 1.00 142.05 ? 115 SER C CA  1 
ATOM 2652 C C   . SER C 2 115 ? 107.431 148.420 138.200 1.00 146.19 ? 115 SER C C   1 
ATOM 2653 O O   . SER C 2 115 ? 108.109 147.390 138.201 1.00 143.63 ? 115 SER C O   1 
ATOM 2654 C CB  . SER C 2 115 ? 108.116 150.561 137.085 1.00 139.48 ? 115 SER C CB  1 
ATOM 2655 O OG  . SER C 2 115 ? 106.832 150.651 136.490 1.00 141.75 ? 115 SER C OG  1 
ATOM 2656 N N   . GLY C 2 116 ? 106.117 148.412 138.018 1.00 150.41 ? 116 GLY C N   1 
ATOM 2657 C CA  . GLY C 2 116 ? 105.381 147.182 137.812 1.00 150.99 ? 116 GLY C CA  1 
ATOM 2658 C C   . GLY C 2 116 ? 104.412 146.886 138.939 1.00 152.86 ? 116 GLY C C   1 
ATOM 2659 O O   . GLY C 2 116 ? 104.118 147.719 139.800 1.00 152.14 ? 116 GLY C O   1 
ATOM 2660 N N   . ASN C 2 117 ? 103.904 145.651 138.917 1.00 150.79 ? 117 ASN C N   1 
ATOM 2661 C CA  . ASN C 2 117 ? 102.936 145.230 139.923 1.00 148.41 ? 117 ASN C CA  1 
ATOM 2662 C C   . ASN C 2 117 ? 103.574 145.089 141.298 1.00 143.23 ? 117 ASN C C   1 
ATOM 2663 O O   . ASN C 2 117 ? 102.879 145.184 142.316 1.00 138.74 ? 117 ASN C O   1 
ATOM 2664 C CB  . ASN C 2 117 ? 102.288 143.910 139.506 1.00 147.04 ? 117 ASN C CB  1 
ATOM 2665 C CG  . ASN C 2 117 ? 101.627 143.989 138.146 1.00 150.19 ? 117 ASN C CG  1 
ATOM 2666 O OD1 . ASN C 2 117 ? 102.276 143.809 137.116 1.00 152.99 ? 117 ASN C OD1 1 
ATOM 2667 N ND2 . ASN C 2 117 ? 100.326 144.256 138.134 1.00 148.45 ? 117 ASN C ND2 1 
ATOM 2668 N N   . PHE C 2 118 ? 104.890 144.869 141.348 1.00 142.05 ? 118 PHE C N   1 
ATOM 2669 C CA  . PHE C 2 118 ? 105.565 144.638 142.622 1.00 139.93 ? 118 PHE C CA  1 
ATOM 2670 C C   . PHE C 2 118 ? 105.383 145.818 143.568 1.00 138.31 ? 118 PHE C C   1 
ATOM 2671 O O   . PHE C 2 118 ? 105.068 145.641 144.750 1.00 136.04 ? 118 PHE C O   1 
ATOM 2672 C CB  . PHE C 2 118 ? 107.051 144.366 142.377 1.00 132.83 ? 118 PHE C CB  1 
ATOM 2673 C CG  . PHE C 2 118 ? 107.867 144.261 143.634 1.00 129.34 ? 118 PHE C CG  1 
ATOM 2674 C CD1 . PHE C 2 118 ? 107.952 143.064 144.321 1.00 126.03 ? 118 PHE C CD1 1 
ATOM 2675 C CD2 . PHE C 2 118 ? 108.558 145.358 144.122 1.00 128.08 ? 118 PHE C CD2 1 
ATOM 2676 C CE1 . PHE C 2 118 ? 108.703 142.966 145.472 1.00 122.12 ? 118 PHE C CE1 1 
ATOM 2677 C CE2 . PHE C 2 118 ? 109.308 145.263 145.276 1.00 123.97 ? 118 PHE C CE2 1 
ATOM 2678 C CZ  . PHE C 2 118 ? 109.380 144.066 145.951 1.00 118.90 ? 118 PHE C CZ  1 
ATOM 2679 N N   . SER C 2 119 ? 105.568 147.037 143.060 1.00 138.88 ? 119 SER C N   1 
ATOM 2680 C CA  . SER C 2 119 ? 105.396 148.221 143.891 1.00 139.22 ? 119 SER C CA  1 
ATOM 2681 C C   . SER C 2 119 ? 103.937 148.508 144.209 1.00 142.01 ? 119 SER C C   1 
ATOM 2682 O O   . SER C 2 119 ? 103.664 149.373 145.048 1.00 141.87 ? 119 SER C O   1 
ATOM 2683 C CB  . SER C 2 119 ? 106.025 149.438 143.210 1.00 138.67 ? 119 SER C CB  1 
ATOM 2684 O OG  . SER C 2 119 ? 105.931 150.585 144.037 1.00 139.96 ? 119 SER C OG  1 
ATOM 2685 N N   . LEU C 2 120 ? 103.000 147.816 143.564 1.00 141.45 ? 120 LEU C N   1 
ATOM 2686 C CA  . LEU C 2 120 ? 101.582 148.031 143.809 1.00 141.77 ? 120 LEU C CA  1 
ATOM 2687 C C   . LEU C 2 120 ? 101.092 147.377 145.094 1.00 140.44 ? 120 LEU C C   1 
ATOM 2688 O O   . LEU C 2 120 ? 100.100 147.840 145.667 1.00 137.24 ? 120 LEU C O   1 
ATOM 2689 C CB  . LEU C 2 120 ? 100.763 147.511 142.622 1.00 138.49 ? 120 LEU C CB  1 
ATOM 2690 C CG  . LEU C 2 120 ? 99.289  147.912 142.564 1.00 135.45 ? 120 LEU C CG  1 
ATOM 2691 C CD1 . LEU C 2 120 ? 99.150  149.426 142.513 1.00 131.54 ? 120 LEU C CD1 1 
ATOM 2692 C CD2 . LEU C 2 120 ? 98.606  147.266 141.369 1.00 133.58 ? 120 LEU C CD2 1 
ATOM 2693 N N   . THR C 2 121 ? 101.761 146.325 145.566 1.00 138.02 ? 121 THR C N   1 
ATOM 2694 C CA  . THR C 2 121 ? 101.350 145.606 146.767 1.00 132.66 ? 121 THR C CA  1 
ATOM 2695 C C   . THR C 2 121 ? 102.536 145.402 147.698 1.00 129.46 ? 121 THR C C   1 
ATOM 2696 O O   . THR C 2 121 ? 102.764 144.302 148.211 1.00 128.26 ? 121 THR C O   1 
ATOM 2697 C CB  . THR C 2 121 ? 100.713 144.260 146.418 1.00 132.16 ? 121 THR C CB  1 
ATOM 2698 O OG1 . THR C 2 121 ? 101.624 143.490 145.624 1.00 132.73 ? 121 THR C OG1 1 
ATOM 2699 C CG2 . THR C 2 121 ? 99.417  144.460 145.646 1.00 132.58 ? 121 THR C CG2 1 
ATOM 2700 N N   . ALA C 2 122 ? 103.310 146.459 147.928 1.00 130.03 ? 122 ALA C N   1 
ATOM 2701 C CA  . ALA C 2 122 ? 104.488 146.401 148.789 1.00 125.95 ? 122 ALA C CA  1 
ATOM 2702 C C   . ALA C 2 122 ? 104.375 147.490 149.846 1.00 124.50 ? 122 ALA C C   1 
ATOM 2703 O O   . ALA C 2 122 ? 104.225 148.669 149.512 1.00 124.59 ? 122 ALA C O   1 
ATOM 2704 C CB  . ALA C 2 122 ? 105.771 146.560 147.975 1.00 123.24 ? 122 ALA C CB  1 
ATOM 2705 N N   . GLU C 2 123 ? 104.453 147.099 151.116 1.00 122.00 ? 123 GLU C N   1 
ATOM 2706 C CA  . GLU C 2 123 ? 104.343 148.028 152.235 1.00 117.92 ? 123 GLU C CA  1 
ATOM 2707 C C   . GLU C 2 123 ? 105.696 148.113 152.929 1.00 112.20 ? 123 GLU C C   1 
ATOM 2708 O O   . GLU C 2 123 ? 106.240 147.096 153.364 1.00 110.39 ? 123 GLU C O   1 
ATOM 2709 C CB  . GLU C 2 123 ? 103.257 147.578 153.210 1.00 118.69 ? 123 GLU C CB  1 
ATOM 2710 C CG  . GLU C 2 123 ? 101.869 147.479 152.599 1.00 122.68 ? 123 GLU C CG  1 
ATOM 2711 C CD  . GLU C 2 123 ? 101.262 148.835 152.296 1.00 126.13 ? 123 GLU C CD  1 
ATOM 2712 O OE1 . GLU C 2 123 ? 101.740 149.844 152.857 1.00 125.52 ? 123 GLU C OE1 1 
ATOM 2713 O OE2 . GLU C 2 123 ? 100.305 148.893 151.496 1.00 130.29 ? 123 GLU C OE2 1 
ATOM 2714 N N   . THR C 2 124 ? 106.232 149.323 153.041 1.00 115.57 ? 124 THR C N   1 
ATOM 2715 C CA  . THR C 2 124 ? 107.509 149.553 153.699 1.00 115.83 ? 124 THR C CA  1 
ATOM 2716 C C   . THR C 2 124 ? 107.294 150.238 155.042 1.00 114.28 ? 124 THR C C   1 
ATOM 2717 O O   . THR C 2 124 ? 106.553 151.220 155.139 1.00 115.70 ? 124 THR C O   1 
ATOM 2718 C CB  . THR C 2 124 ? 108.433 150.402 152.823 1.00 111.22 ? 124 THR C CB  1 
ATOM 2719 O OG1 . THR C 2 124 ? 109.744 150.433 153.400 1.00 106.85 ? 124 THR C OG1 1 
ATOM 2720 C CG2 . THR C 2 124 ? 107.900 151.818 152.700 1.00 112.16 ? 124 THR C CG2 1 
ATOM 2721 N N   . GLU C 2 125 ? 107.945 149.712 156.077 1.00 108.60 ? 125 GLU C N   1 
ATOM 2722 C CA  . GLU C 2 125 ? 107.824 150.249 157.426 1.00 108.95 ? 125 GLU C CA  1 
ATOM 2723 C C   . GLU C 2 125 ? 109.208 150.416 158.030 1.00 108.09 ? 125 GLU C C   1 
ATOM 2724 O O   . GLU C 2 125 ? 109.999 149.470 158.040 1.00 108.01 ? 125 GLU C O   1 
ATOM 2725 C CB  . GLU C 2 125 ? 106.974 149.333 158.313 1.00 113.72 ? 125 GLU C CB  1 
ATOM 2726 C CG  . GLU C 2 125 ? 105.528 149.199 157.869 1.00 123.03 ? 125 GLU C CG  1 
ATOM 2727 C CD  . GLU C 2 125 ? 104.711 148.330 158.805 1.00 128.98 ? 125 GLU C CD  1 
ATOM 2728 O OE1 . GLU C 2 125 ? 105.302 147.731 159.728 1.00 122.23 ? 125 GLU C OE1 1 
ATOM 2729 O OE2 . GLU C 2 125 ? 103.479 148.248 158.618 1.00 135.01 ? 125 GLU C OE2 1 
ATOM 2730 N N   . GLU C 2 126 ? 109.492 151.609 158.540 1.00 111.22 ? 126 GLU C N   1 
ATOM 2731 C CA  . GLU C 2 126 ? 110.768 151.889 159.181 1.00 107.23 ? 126 GLU C CA  1 
ATOM 2732 C C   . GLU C 2 126 ? 110.666 151.626 160.677 1.00 106.47 ? 126 GLU C C   1 
ATOM 2733 O O   . GLU C 2 126 ? 109.716 152.063 161.333 1.00 108.65 ? 126 GLU C O   1 
ATOM 2734 C CB  . GLU C 2 126 ? 111.196 153.335 158.926 1.00 107.95 ? 126 GLU C CB  1 
ATOM 2735 C CG  . GLU C 2 126 ? 111.608 153.628 157.488 1.00 113.52 ? 126 GLU C CG  1 
ATOM 2736 C CD  . GLU C 2 126 ? 110.452 153.561 156.503 1.00 117.44 ? 126 GLU C CD  1 
ATOM 2737 O OE1 . GLU C 2 126 ? 109.284 153.569 156.945 1.00 117.20 ? 126 GLU C OE1 1 
ATOM 2738 O OE2 . GLU C 2 126 ? 110.710 153.496 155.284 1.00 115.69 ? 126 GLU C OE2 1 
ATOM 2739 N N   . ARG C 2 127 ? 111.650 150.910 161.211 1.00 106.59 ? 127 ARG C N   1 
ATOM 2740 C CA  . ARG C 2 127 ? 111.621 150.475 162.601 1.00 106.90 ? 127 ARG C CA  1 
ATOM 2741 C C   . ARG C 2 127 ? 113.010 150.663 163.200 1.00 105.64 ? 127 ARG C C   1 
ATOM 2742 O O   . ARG C 2 127 ? 113.861 151.358 162.636 1.00 107.53 ? 127 ARG C O   1 
ATOM 2743 C CB  . ARG C 2 127 ? 111.126 149.027 162.707 1.00 104.26 ? 127 ARG C CB  1 
ATOM 2744 C CG  . ARG C 2 127 ? 109.707 148.831 162.203 1.00 108.02 ? 127 ARG C CG  1 
ATOM 2745 C CD  . ARG C 2 127 ? 109.130 147.491 162.621 1.00 115.15 ? 127 ARG C CD  1 
ATOM 2746 N NE  . ARG C 2 127 ? 107.757 147.335 162.157 1.00 117.05 ? 127 ARG C NE  1 
ATOM 2747 C CZ  . ARG C 2 127 ? 106.983 146.296 162.436 1.00 116.00 ? 127 ARG C CZ  1 
ATOM 2748 N NH1 . ARG C 2 127 ? 107.415 145.294 163.185 1.00 115.99 ? 127 ARG C NH1 1 
ATOM 2749 N NH2 . ARG C 2 127 ? 105.744 146.261 161.953 1.00 111.46 ? 127 ARG C NH2 1 
ATOM 2750 N N   . ASN C 2 128 ? 113.240 150.039 164.351 1.00 103.21 ? 128 ASN C N   1 
ATOM 2751 C CA  . ASN C 2 128 ? 114.408 150.293 165.189 1.00 107.16 ? 128 ASN C CA  1 
ATOM 2752 C C   . ASN C 2 128 ? 115.064 148.981 165.607 1.00 107.27 ? 128 ASN C C   1 
ATOM 2753 O O   . ASN C 2 128 ? 115.244 148.699 166.793 1.00 108.53 ? 128 ASN C O   1 
ATOM 2754 C CB  . ASN C 2 128 ? 114.019 151.126 166.407 1.00 111.70 ? 128 ASN C CB  1 
ATOM 2755 C CG  . ASN C 2 128 ? 115.207 151.825 167.042 1.00 116.76 ? 128 ASN C CG  1 
ATOM 2756 O OD1 . ASN C 2 128 ? 116.345 151.374 166.922 1.00 115.80 ? 128 ASN C OD1 1 
ATOM 2757 N ND2 . ASN C 2 128 ? 114.944 152.934 167.724 1.00 117.43 ? 128 ASN C ND2 1 
ATOM 2758 N N   . PHE C 2 129 ? 115.409 148.148 164.624 1.00 105.01 ? 129 PHE C N   1 
ATOM 2759 C CA  . PHE C 2 129 ? 116.039 146.853 164.864 1.00 100.50 ? 129 PHE C CA  1 
ATOM 2760 C C   . PHE C 2 129 ? 117.327 147.003 165.663 1.00 104.75 ? 129 PHE C C   1 
ATOM 2761 O O   . PHE C 2 129 ? 118.061 147.983 165.485 1.00 106.37 ? 129 PHE C O   1 
ATOM 2762 C CB  . PHE C 2 129 ? 116.361 146.144 163.549 1.00 97.92  ? 129 PHE C CB  1 
ATOM 2763 C CG  . PHE C 2 129 ? 115.176 145.913 162.672 1.00 97.85  ? 129 PHE C CG  1 
ATOM 2764 C CD1 . PHE C 2 129 ? 114.304 144.873 162.925 1.00 97.96  ? 129 PHE C CD1 1 
ATOM 2765 C CD2 . PHE C 2 129 ? 114.946 146.723 161.578 1.00 96.73  ? 129 PHE C CD2 1 
ATOM 2766 C CE1 . PHE C 2 129 ? 113.218 144.656 162.112 1.00 98.29  ? 129 PHE C CE1 1 
ATOM 2767 C CE2 . PHE C 2 129 ? 113.861 146.509 160.762 1.00 97.73  ? 129 PHE C CE2 1 
ATOM 2768 C CZ  . PHE C 2 129 ? 112.996 145.474 161.030 1.00 98.21  ? 129 PHE C CZ  1 
ATOM 2769 N N   . PRO C 2 130 ? 117.630 146.062 166.551 1.00 105.80 ? 130 PRO C N   1 
ATOM 2770 C CA  . PRO C 2 130 ? 118.907 146.109 167.267 1.00 106.84 ? 130 PRO C CA  1 
ATOM 2771 C C   . PRO C 2 130 ? 120.080 145.873 166.330 1.00 102.01 ? 130 PRO C C   1 
ATOM 2772 O O   . PRO C 2 130 ? 119.962 145.203 165.302 1.00 98.09  ? 130 PRO C O   1 
ATOM 2773 C CB  . PRO C 2 130 ? 118.779 144.977 168.290 1.00 106.55 ? 130 PRO C CB  1 
ATOM 2774 C CG  . PRO C 2 130 ? 117.812 144.033 167.668 1.00 104.13 ? 130 PRO C CG  1 
ATOM 2775 C CD  . PRO C 2 130 ? 116.831 144.883 166.919 1.00 102.93 ? 130 PRO C CD  1 
ATOM 2776 N N   . GLN C 2 131 ? 121.230 146.434 166.703 1.00 102.82 ? 131 GLN C N   1 
ATOM 2777 C CA  . GLN C 2 131 ? 122.449 146.317 165.916 1.00 99.79  ? 131 GLN C CA  1 
ATOM 2778 C C   . GLN C 2 131 ? 123.283 145.101 166.299 1.00 99.68  ? 131 GLN C C   1 
ATOM 2779 O O   . GLN C 2 131 ? 124.499 145.099 166.077 1.00 94.04  ? 131 GLN C O   1 
ATOM 2780 C CB  . GLN C 2 131 ? 123.287 147.589 166.053 1.00 98.99  ? 131 GLN C CB  1 
ATOM 2781 C CG  . GLN C 2 131 ? 122.506 148.872 165.825 1.00 99.32  ? 131 GLN C CG  1 
ATOM 2782 C CD  . GLN C 2 131 ? 121.962 148.987 164.416 1.00 96.86  ? 131 GLN C CD  1 
ATOM 2783 O OE1 . GLN C 2 131 ? 122.485 148.378 163.484 1.00 97.39  ? 131 GLN C OE1 1 
ATOM 2784 N NE2 . GLN C 2 131 ? 120.902 149.770 164.254 1.00 93.97  ? 131 GLN C NE2 1 
ATOM 2785 N N   . GLU C 2 132 ? 122.661 144.074 166.871 1.00 104.72 ? 132 GLU C N   1 
ATOM 2786 C CA  . GLU C 2 132 ? 123.340 142.847 167.257 1.00 105.67 ? 132 GLU C CA  1 
ATOM 2787 C C   . GLU C 2 132 ? 122.675 141.670 166.560 1.00 107.11 ? 132 GLU C C   1 
ATOM 2788 O O   . GLU C 2 132 ? 121.452 141.648 166.398 1.00 108.39 ? 132 GLU C O   1 
ATOM 2789 C CB  . GLU C 2 132 ? 123.306 142.650 168.777 1.00 106.57 ? 132 GLU C CB  1 
ATOM 2790 C CG  . GLU C 2 132 ? 124.073 141.436 169.275 1.00 107.07 ? 132 GLU C CG  1 
ATOM 2791 C CD  . GLU C 2 132 ? 125.575 141.604 169.164 1.00 110.70 ? 132 GLU C CD  1 
ATOM 2792 O OE1 . GLU C 2 132 ? 126.039 142.755 169.022 1.00 111.72 ? 132 GLU C OE1 1 
ATOM 2793 O OE2 . GLU C 2 132 ? 126.293 140.585 169.222 1.00 115.80 ? 132 GLU C OE2 1 
ATOM 2794 N N   . ASN C 2 133 ? 123.486 140.696 166.143 1.00 103.39 ? 133 ASN C N   1 
ATOM 2795 C CA  . ASN C 2 133 ? 122.954 139.562 165.396 1.00 101.46 ? 133 ASN C CA  1 
ATOM 2796 C C   . ASN C 2 133 ? 121.963 138.762 166.230 1.00 106.16 ? 133 ASN C C   1 
ATOM 2797 O O   . ASN C 2 133 ? 120.851 138.466 165.779 1.00 101.81 ? 133 ASN C O   1 
ATOM 2798 C CB  . ASN C 2 133 ? 124.095 138.666 164.921 1.00 94.55  ? 133 ASN C CB  1 
ATOM 2799 C CG  . ASN C 2 133 ? 124.755 139.185 163.670 1.00 88.67  ? 133 ASN C CG  1 
ATOM 2800 O OD1 . ASN C 2 133 ? 124.746 140.384 163.401 1.00 88.07  ? 133 ASN C OD1 1 
ATOM 2801 N ND2 . ASN C 2 133 ? 125.326 138.280 162.889 1.00 87.95  ? 133 ASN C ND2 1 
ATOM 2802 N N   . GLU C 2 134 ? 122.353 138.393 167.450 1.00 110.74 ? 134 GLU C N   1 
ATOM 2803 C CA  . GLU C 2 134 ? 121.476 137.574 168.278 1.00 112.01 ? 134 GLU C CA  1 
ATOM 2804 C C   . GLU C 2 134 ? 120.197 138.319 168.636 1.00 109.12 ? 134 GLU C C   1 
ATOM 2805 O O   . GLU C 2 134 ? 119.102 137.750 168.572 1.00 106.76 ? 134 GLU C O   1 
ATOM 2806 C CB  . GLU C 2 134 ? 122.212 137.121 169.539 1.00 109.71 ? 134 GLU C CB  1 
ATOM 2807 C CG  . GLU C 2 134 ? 123.377 136.182 169.263 1.00 107.51 ? 134 GLU C CG  1 
ATOM 2808 C CD  . GLU C 2 134 ? 122.948 134.898 168.574 1.00 106.79 ? 134 GLU C CD  1 
ATOM 2809 O OE1 . GLU C 2 134 ? 121.801 134.453 168.792 1.00 108.64 ? 134 GLU C OE1 1 
ATOM 2810 O OE2 . GLU C 2 134 ? 123.759 134.332 167.810 1.00 103.63 ? 134 GLU C OE2 1 
ATOM 2811 N N   . HIS C 2 135 ? 120.313 139.597 169.001 1.00 110.31 ? 135 HIS C N   1 
ATOM 2812 C CA  . HIS C 2 135 ? 119.126 140.374 169.343 1.00 110.75 ? 135 HIS C CA  1 
ATOM 2813 C C   . HIS C 2 135 ? 118.197 140.524 168.144 1.00 113.45 ? 135 HIS C C   1 
ATOM 2814 O O   . HIS C 2 135 ? 116.975 140.395 168.278 1.00 118.33 ? 135 HIS C O   1 
ATOM 2815 C CB  . HIS C 2 135 ? 119.533 141.744 169.881 1.00 111.25 ? 135 HIS C CB  1 
ATOM 2816 C CG  . HIS C 2 135 ? 120.312 141.685 171.157 1.00 120.34 ? 135 HIS C CG  1 
ATOM 2817 N ND1 . HIS C 2 135 ? 120.407 140.540 171.919 1.00 125.85 ? 135 HIS C ND1 1 
ATOM 2818 C CD2 . HIS C 2 135 ? 121.035 142.629 171.805 1.00 126.07 ? 135 HIS C CD2 1 
ATOM 2819 C CE1 . HIS C 2 135 ? 121.153 140.782 172.982 1.00 131.21 ? 135 HIS C CE1 1 
ATOM 2820 N NE2 . HIS C 2 135 ? 121.547 142.042 172.937 1.00 131.05 ? 135 HIS C NE2 1 
ATOM 2821 N N   . LEU C 2 136 ? 118.757 140.802 166.964 1.00 110.72 ? 136 LEU C N   1 
ATOM 2822 C CA  . LEU C 2 136 ? 117.932 140.960 165.770 1.00 107.10 ? 136 LEU C CA  1 
ATOM 2823 C C   . LEU C 2 136 ? 117.245 139.655 165.394 1.00 103.56 ? 136 LEU C C   1 
ATOM 2824 O O   . LEU C 2 136 ? 116.061 139.648 165.035 1.00 102.79 ? 136 LEU C O   1 
ATOM 2825 C CB  . LEU C 2 136 ? 118.782 141.474 164.611 1.00 97.18  ? 136 LEU C CB  1 
ATOM 2826 C CG  . LEU C 2 136 ? 118.103 141.591 163.248 1.00 86.30  ? 136 LEU C CG  1 
ATOM 2827 C CD1 . LEU C 2 136 ? 116.846 142.431 163.335 1.00 88.83  ? 136 LEU C CD1 1 
ATOM 2828 C CD2 . LEU C 2 136 ? 119.067 142.184 162.243 1.00 79.61  ? 136 LEU C CD2 1 
ATOM 2829 N N   . LEU C 2 137 ? 117.971 138.541 165.472 1.00 98.73  ? 137 LEU C N   1 
ATOM 2830 C CA  . LEU C 2 137 ? 117.365 137.251 165.172 1.00 101.14 ? 137 LEU C CA  1 
ATOM 2831 C C   . LEU C 2 137 ? 116.264 136.918 166.171 1.00 108.14 ? 137 LEU C C   1 
ATOM 2832 O O   . LEU C 2 137 ? 115.208 136.402 165.791 1.00 108.14 ? 137 LEU C O   1 
ATOM 2833 C CB  . LEU C 2 137 ? 118.433 136.160 165.159 1.00 99.28  ? 137 LEU C CB  1 
ATOM 2834 C CG  . LEU C 2 137 ? 117.946 134.805 164.654 1.00 97.42  ? 137 LEU C CG  1 
ATOM 2835 C CD1 . LEU C 2 137 ? 117.482 134.941 163.226 1.00 85.33  ? 137 LEU C CD1 1 
ATOM 2836 C CD2 . LEU C 2 137 ? 119.036 133.758 164.770 1.00 98.89  ? 137 LEU C CD2 1 
ATOM 2837 N N   . ARG C 2 138 ? 116.491 137.206 167.456 1.00 108.61 ? 138 ARG C N   1 
ATOM 2838 C CA  . ARG C 2 138 ? 115.461 136.961 168.460 1.00 109.99 ? 138 ARG C CA  1 
ATOM 2839 C C   . ARG C 2 138 ? 114.228 137.813 168.205 1.00 109.58 ? 138 ARG C C   1 
ATOM 2840 O O   . ARG C 2 138 ? 113.097 137.330 168.324 1.00 110.37 ? 138 ARG C O   1 
ATOM 2841 C CB  . ARG C 2 138 ? 116.011 137.232 169.860 1.00 114.35 ? 138 ARG C CB  1 
ATOM 2842 C CG  . ARG C 2 138 ? 116.995 136.192 170.364 1.00 116.56 ? 138 ARG C CG  1 
ATOM 2843 C CD  . ARG C 2 138 ? 117.461 136.523 171.774 1.00 121.31 ? 138 ARG C CD  1 
ATOM 2844 N NE  . ARG C 2 138 ? 118.436 135.559 172.270 1.00 130.41 ? 138 ARG C NE  1 
ATOM 2845 C CZ  . ARG C 2 138 ? 119.033 135.638 173.451 1.00 136.94 ? 138 ARG C CZ  1 
ATOM 2846 N NH1 . ARG C 2 138 ? 118.777 136.629 174.290 1.00 137.75 ? 138 ARG C NH1 1 
ATOM 2847 N NH2 . ARG C 2 138 ? 119.910 134.700 173.799 1.00 138.53 ? 138 ARG C NH2 1 
ATOM 2848 N N   . TRP C 2 139 ? 114.424 139.088 167.862 1.00 110.16 ? 139 TRP C N   1 
ATOM 2849 C CA  . TRP C 2 139 ? 113.292 139.963 167.579 1.00 110.05 ? 139 TRP C CA  1 
ATOM 2850 C C   . TRP C 2 139 ? 112.501 139.452 166.384 1.00 112.00 ? 139 TRP C C   1 
ATOM 2851 O O   . TRP C 2 139 ? 111.265 139.411 166.411 1.00 111.41 ? 139 TRP C O   1 
ATOM 2852 C CB  . TRP C 2 139 ? 113.789 141.387 167.329 1.00 108.18 ? 139 TRP C CB  1 
ATOM 2853 C CG  . TRP C 2 139 ? 112.699 142.409 167.188 1.00 110.08 ? 139 TRP C CG  1 
ATOM 2854 C CD1 . TRP C 2 139 ? 112.243 143.256 168.155 1.00 109.57 ? 139 TRP C CD1 1 
ATOM 2855 C CD2 . TRP C 2 139 ? 111.936 142.699 166.010 1.00 113.15 ? 139 TRP C CD2 1 
ATOM 2856 N NE1 . TRP C 2 139 ? 111.242 144.052 167.655 1.00 110.40 ? 139 TRP C NE1 1 
ATOM 2857 C CE2 . TRP C 2 139 ? 111.035 143.730 166.339 1.00 114.62 ? 139 TRP C CE2 1 
ATOM 2858 C CE3 . TRP C 2 139 ? 111.926 142.187 164.709 1.00 110.93 ? 139 TRP C CE3 1 
ATOM 2859 C CZ2 . TRP C 2 139 ? 110.135 144.257 165.417 1.00 117.30 ? 139 TRP C CZ2 1 
ATOM 2860 C CZ3 . TRP C 2 139 ? 111.030 142.709 163.797 1.00 110.09 ? 139 TRP C CZ3 1 
ATOM 2861 C CH2 . TRP C 2 139 ? 110.149 143.735 164.154 1.00 115.75 ? 139 TRP C CH2 1 
ATOM 2862 N N   . ALA C 2 140 ? 113.204 139.052 165.323 1.00 109.36 ? 140 ALA C N   1 
ATOM 2863 C CA  . ALA C 2 140 ? 112.528 138.535 164.139 1.00 109.80 ? 140 ALA C CA  1 
ATOM 2864 C C   . ALA C 2 140 ? 111.766 137.254 164.449 1.00 115.01 ? 140 ALA C C   1 
ATOM 2865 O O   . ALA C 2 140 ? 110.625 137.078 164.005 1.00 118.15 ? 140 ALA C O   1 
ATOM 2866 C CB  . ALA C 2 140 ? 113.543 138.298 163.025 1.00 103.66 ? 140 ALA C CB  1 
ATOM 2867 N N   . GLN C 2 141 ? 112.380 136.346 165.210 1.00 111.62 ? 141 GLN C N   1 
ATOM 2868 C CA  . GLN C 2 141 ? 111.712 135.098 165.560 1.00 110.31 ? 141 GLN C CA  1 
ATOM 2869 C C   . GLN C 2 141 ? 110.484 135.351 166.426 1.00 114.24 ? 141 GLN C C   1 
ATOM 2870 O O   . GLN C 2 141 ? 109.444 134.711 166.241 1.00 110.63 ? 141 GLN C O   1 
ATOM 2871 C CB  . GLN C 2 141 ? 112.689 134.165 166.271 1.00 108.33 ? 141 GLN C CB  1 
ATOM 2872 C CG  . GLN C 2 141 ? 113.771 133.605 165.373 1.00 109.42 ? 141 GLN C CG  1 
ATOM 2873 C CD  . GLN C 2 141 ? 114.835 132.858 166.148 1.00 116.32 ? 141 GLN C CD  1 
ATOM 2874 O OE1 . GLN C 2 141 ? 115.256 133.291 167.220 1.00 115.61 ? 141 GLN C OE1 1 
ATOM 2875 N NE2 . GLN C 2 141 ? 115.273 131.727 165.611 1.00 114.80 ? 141 GLN C NE2 1 
ATOM 2876 N N   . LYS C 2 142 ? 110.587 136.273 167.384 1.00 115.74 ? 142 LYS C N   1 
ATOM 2877 C CA  . LYS C 2 142 ? 109.438 136.589 168.224 1.00 111.89 ? 142 LYS C CA  1 
ATOM 2878 C C   . LYS C 2 142 ? 108.312 137.209 167.409 1.00 114.89 ? 142 LYS C C   1 
ATOM 2879 O O   . LYS C 2 142 ? 107.139 136.869 167.603 1.00 120.90 ? 142 LYS C O   1 
ATOM 2880 C CB  . LYS C 2 142 ? 109.857 137.525 169.356 1.00 107.51 ? 142 LYS C CB  1 
ATOM 2881 C CG  . LYS C 2 142 ? 108.710 137.974 170.243 1.00 111.71 ? 142 LYS C CG  1 
ATOM 2882 C CD  . LYS C 2 142 ? 109.184 138.944 171.310 1.00 115.00 ? 142 LYS C CD  1 
ATOM 2883 C CE  . LYS C 2 142 ? 108.026 139.424 172.168 1.00 117.28 ? 142 LYS C CE  1 
ATOM 2884 N NZ  . LYS C 2 142 ? 107.328 138.291 172.836 1.00 112.55 ? 142 LYS C NZ  1 
ATOM 2885 N N   . GLU C 2 143 ? 108.646 138.114 166.489 1.00 110.65 ? 143 GLU C N   1 
ATOM 2886 C CA  . GLU C 2 143 ? 107.607 138.802 165.731 1.00 110.20 ? 143 GLU C CA  1 
ATOM 2887 C C   . GLU C 2 143 ? 106.940 137.879 164.719 1.00 108.82 ? 143 GLU C C   1 
ATOM 2888 O O   . GLU C 2 143 ? 105.722 137.947 164.522 1.00 104.57 ? 143 GLU C O   1 
ATOM 2889 C CB  . GLU C 2 143 ? 108.195 140.026 165.033 1.00 112.48 ? 143 GLU C CB  1 
ATOM 2890 C CG  . GLU C 2 143 ? 108.527 141.173 165.969 1.00 120.57 ? 143 GLU C CG  1 
ATOM 2891 C CD  . GLU C 2 143 ? 107.303 141.974 166.369 1.00 127.09 ? 143 GLU C CD  1 
ATOM 2892 O OE1 . GLU C 2 143 ? 106.237 141.788 165.744 1.00 125.03 ? 143 GLU C OE1 1 
ATOM 2893 O OE2 . GLU C 2 143 ? 107.407 142.793 167.306 1.00 130.63 ? 143 GLU C OE2 1 
ATOM 2894 N N   . TYR C 2 144 ? 107.715 137.008 164.064 1.00 110.03 ? 144 TYR C N   1 
ATOM 2895 C CA  . TYR C 2 144 ? 107.187 136.224 162.953 1.00 107.96 ? 144 TYR C CA  1 
ATOM 2896 C C   . TYR C 2 144 ? 107.462 134.731 163.094 1.00 107.17 ? 144 TYR C C   1 
ATOM 2897 O O   . TYR C 2 144 ? 107.471 134.015 162.089 1.00 105.94 ? 144 TYR C O   1 
ATOM 2898 C CB  . TYR C 2 144 ? 107.750 136.732 161.625 1.00 103.97 ? 144 TYR C CB  1 
ATOM 2899 C CG  . TYR C 2 144 ? 107.324 138.137 161.287 1.00 106.59 ? 144 TYR C CG  1 
ATOM 2900 C CD1 . TYR C 2 144 ? 106.103 138.382 160.680 1.00 107.36 ? 144 TYR C CD1 1 
ATOM 2901 C CD2 . TYR C 2 144 ? 108.142 139.217 161.575 1.00 106.88 ? 144 TYR C CD2 1 
ATOM 2902 C CE1 . TYR C 2 144 ? 105.708 139.664 160.370 1.00 108.30 ? 144 TYR C CE1 1 
ATOM 2903 C CE2 . TYR C 2 144 ? 107.756 140.503 161.269 1.00 109.74 ? 144 TYR C CE2 1 
ATOM 2904 C CZ  . TYR C 2 144 ? 106.538 140.721 160.666 1.00 111.48 ? 144 TYR C CZ  1 
ATOM 2905 O OH  . TYR C 2 144 ? 106.145 142.002 160.358 1.00 114.92 ? 144 TYR C OH  1 
ATOM 2906 N N   . GLY C 2 145 ? 107.691 134.243 164.307 1.00 108.20 ? 145 GLY C N   1 
ATOM 2907 C CA  . GLY C 2 145 ? 107.809 132.814 164.513 1.00 108.81 ? 145 GLY C CA  1 
ATOM 2908 C C   . GLY C 2 145 ? 109.167 132.254 164.148 1.00 109.09 ? 145 GLY C C   1 
ATOM 2909 O O   . GLY C 2 145 ? 109.975 131.942 165.027 1.00 111.54 ? 145 GLY C O   1 
ATOM 2910 N N   . ALA C 2 146 ? 109.432 132.124 162.850 1.00 105.16 ? 146 ALA C N   1 
ATOM 2911 C CA  . ALA C 2 146 ? 110.679 131.559 162.355 1.00 96.16  ? 146 ALA C CA  1 
ATOM 2912 C C   . ALA C 2 146 ? 111.130 132.333 161.128 1.00 94.42  ? 146 ALA C C   1 
ATOM 2913 O O   . ALA C 2 146 ? 110.303 132.729 160.301 1.00 97.45  ? 146 ALA C O   1 
ATOM 2914 C CB  . ALA C 2 146 ? 110.520 130.074 162.017 1.00 96.27  ? 146 ALA C CB  1 
ATOM 2915 N N   . VAL C 2 147 ? 112.436 132.541 161.012 1.00 91.87  ? 147 VAL C N   1 
ATOM 2916 C CA  . VAL C 2 147 ? 113.016 133.276 159.896 1.00 85.47  ? 147 VAL C CA  1 
ATOM 2917 C C   . VAL C 2 147 ? 113.378 132.290 158.796 1.00 84.57  ? 147 VAL C C   1 
ATOM 2918 O O   . VAL C 2 147 ? 114.016 131.264 159.052 1.00 90.96  ? 147 VAL C O   1 
ATOM 2919 C CB  . VAL C 2 147 ? 114.247 134.077 160.341 1.00 86.00  ? 147 VAL C CB  1 
ATOM 2920 C CG1 . VAL C 2 147 ? 113.824 135.262 161.170 1.00 93.78  ? 147 VAL C CG1 1 
ATOM 2921 C CG2 . VAL C 2 147 ? 115.185 133.193 161.137 1.00 89.70  ? 147 VAL C CG2 1 
ATOM 2922 N N   . THR C 2 148 ? 112.964 132.591 157.566 1.00 83.87  ? 148 THR C N   1 
ATOM 2923 C CA  . THR C 2 148 ? 113.347 131.740 156.448 1.00 83.91  ? 148 THR C CA  1 
ATOM 2924 C C   . THR C 2 148 ? 114.820 131.912 156.113 1.00 80.13  ? 148 THR C C   1 
ATOM 2925 O O   . THR C 2 148 ? 115.459 130.984 155.606 1.00 80.37  ? 148 THR C O   1 
ATOM 2926 C CB  . THR C 2 148 ? 112.490 132.047 155.225 1.00 88.74  ? 148 THR C CB  1 
ATOM 2927 O OG1 . THR C 2 148 ? 111.158 132.363 155.642 1.00 99.82  ? 148 THR C OG1 1 
ATOM 2928 C CG2 . THR C 2 148 ? 112.448 130.845 154.301 1.00 85.29  ? 148 THR C CG2 1 
ATOM 2929 N N   . SER C 2 149 ? 115.376 133.089 156.386 1.00 77.33  ? 149 SER C N   1 
ATOM 2930 C CA  . SER C 2 149 ? 116.771 133.353 156.075 1.00 67.30  ? 149 SER C CA  1 
ATOM 2931 C C   . SER C 2 149 ? 117.266 134.518 156.912 1.00 63.92  ? 149 SER C C   1 
ATOM 2932 O O   . SER C 2 149 ? 116.532 135.478 157.142 1.00 73.96  ? 149 SER C O   1 
ATOM 2933 C CB  . SER C 2 149 ? 116.951 133.664 154.588 1.00 66.07  ? 149 SER C CB  1 
ATOM 2934 O OG  . SER C 2 149 ? 118.221 134.234 154.335 1.00 62.57  ? 149 SER C OG  1 
ATOM 2935 N N   . PHE C 2 150 ? 118.516 134.432 157.355 1.00 57.20  ? 150 PHE C N   1 
ATOM 2936 C CA  . PHE C 2 150 ? 119.188 135.528 158.034 1.00 56.19  ? 150 PHE C CA  1 
ATOM 2937 C C   . PHE C 2 150 ? 120.607 135.589 157.507 1.00 58.44  ? 150 PHE C C   1 
ATOM 2938 O O   . PHE C 2 150 ? 121.257 134.551 157.368 1.00 69.68  ? 150 PHE C O   1 
ATOM 2939 C CB  . PHE C 2 150 ? 119.199 135.335 159.556 1.00 58.45  ? 150 PHE C CB  1 
ATOM 2940 C CG  . PHE C 2 150 ? 119.917 136.426 160.303 1.00 63.24  ? 150 PHE C CG  1 
ATOM 2941 C CD1 . PHE C 2 150 ? 121.282 136.367 160.507 1.00 64.31  ? 150 PHE C CD1 1 
ATOM 2942 C CD2 . PHE C 2 150 ? 119.224 137.503 160.812 1.00 66.70  ? 150 PHE C CD2 1 
ATOM 2943 C CE1 . PHE C 2 150 ? 121.936 137.369 161.187 1.00 66.36  ? 150 PHE C CE1 1 
ATOM 2944 C CE2 . PHE C 2 150 ? 119.874 138.505 161.494 1.00 69.45  ? 150 PHE C CE2 1 
ATOM 2945 C CZ  . PHE C 2 150 ? 121.230 138.436 161.684 1.00 67.85  ? 150 PHE C CZ  1 
ATOM 2946 N N   . THR C 2 151 ? 121.089 136.793 157.224 1.00 54.77  ? 151 THR C N   1 
ATOM 2947 C CA  . THR C 2 151 ? 122.452 136.962 156.743 1.00 56.14  ? 151 THR C CA  1 
ATOM 2948 C C   . THR C 2 151 ? 123.019 138.273 157.253 1.00 55.36  ? 151 THR C C   1 
ATOM 2949 O O   . THR C 2 151 ? 122.424 139.331 157.041 1.00 60.07  ? 151 THR C O   1 
ATOM 2950 C CB  . THR C 2 151 ? 122.511 136.928 155.214 1.00 55.21  ? 151 THR C CB  1 
ATOM 2951 O OG1 . THR C 2 151 ? 121.688 137.970 154.681 1.00 50.54  ? 151 THR C OG1 1 
ATOM 2952 C CG2 . THR C 2 151 ? 122.032 135.590 154.688 1.00 52.76  ? 151 THR C CG2 1 
ATOM 2953 N N   . GLU C 2 152 ? 124.158 138.203 157.927 1.00 55.16  ? 152 GLU C N   1 
ATOM 2954 C CA  . GLU C 2 152 ? 124.926 139.381 158.295 1.00 58.14  ? 152 GLU C CA  1 
ATOM 2955 C C   . GLU C 2 152 ? 126.079 139.525 157.318 1.00 62.56  ? 152 GLU C C   1 
ATOM 2956 O O   . GLU C 2 152 ? 126.865 138.587 157.136 1.00 69.55  ? 152 GLU C O   1 
ATOM 2957 C CB  . GLU C 2 152 ? 125.466 139.279 159.719 1.00 67.18  ? 152 GLU C CB  1 
ATOM 2958 C CG  . GLU C 2 152 ? 126.432 140.395 160.070 1.00 73.33  ? 152 GLU C CG  1 
ATOM 2959 C CD  . GLU C 2 152 ? 127.277 140.083 161.283 1.00 80.85  ? 152 GLU C CD  1 
ATOM 2960 O OE1 . GLU C 2 152 ? 127.238 138.929 161.754 1.00 86.28  ? 152 GLU C OE1 1 
ATOM 2961 O OE2 . GLU C 2 152 ? 127.983 140.991 161.767 1.00 83.62  ? 152 GLU C OE2 1 
ATOM 2962 N N   . LEU C 2 153 ? 126.184 140.701 156.708 1.00 58.75  ? 153 LEU C N   1 
ATOM 2963 C CA  . LEU C 2 153 ? 127.158 140.922 155.650 1.00 61.51  ? 153 LEU C CA  1 
ATOM 2964 C C   . LEU C 2 153 ? 127.598 142.375 155.650 1.00 65.09  ? 153 LEU C C   1 
ATOM 2965 O O   . LEU C 2 153 ? 126.919 143.248 156.186 1.00 71.20  ? 153 LEU C O   1 
ATOM 2966 C CB  . LEU C 2 153 ? 126.582 140.533 154.284 1.00 57.60  ? 153 LEU C CB  1 
ATOM 2967 C CG  . LEU C 2 153 ? 125.115 140.876 154.020 1.00 54.92  ? 153 LEU C CG  1 
ATOM 2968 C CD1 . LEU C 2 153 ? 124.942 142.324 153.612 1.00 57.61  ? 153 LEU C CD1 1 
ATOM 2969 C CD2 . LEU C 2 153 ? 124.535 139.952 152.967 1.00 54.81  ? 153 LEU C CD2 1 
ATOM 2970 N N   . LYS C 2 154 ? 128.754 142.627 155.045 1.00 65.48  ? 154 LYS C N   1 
ATOM 2971 C CA  . LYS C 2 154 ? 129.209 143.997 154.878 1.00 70.63  ? 154 LYS C CA  1 
ATOM 2972 C C   . LYS C 2 154 ? 128.323 144.726 153.877 1.00 72.60  ? 154 LYS C C   1 
ATOM 2973 O O   . LYS C 2 154 ? 127.665 144.116 153.034 1.00 79.48  ? 154 LYS C O   1 
ATOM 2974 C CB  . LYS C 2 154 ? 130.660 144.030 154.408 1.00 72.24  ? 154 LYS C CB  1 
ATOM 2975 C CG  . LYS C 2 154 ? 131.662 143.577 155.450 1.00 76.37  ? 154 LYS C CG  1 
ATOM 2976 C CD  . LYS C 2 154 ? 133.061 143.516 154.869 1.00 80.14  ? 154 LYS C CD  1 
ATOM 2977 C CE  . LYS C 2 154 ? 133.420 144.820 154.181 1.00 91.85  ? 154 LYS C CE  1 
ATOM 2978 N NZ  . LYS C 2 154 ? 133.246 145.983 155.090 1.00 96.57  ? 154 LYS C NZ  1 
ATOM 2979 N N   . ILE C 2 155 ? 128.306 146.051 153.978 1.00 74.11  ? 155 ILE C N   1 
ATOM 2980 C CA  . ILE C 2 155 ? 127.479 146.846 153.078 1.00 78.78  ? 155 ILE C CA  1 
ATOM 2981 C C   . ILE C 2 155 ? 128.128 146.869 151.702 1.00 82.94  ? 155 ILE C C   1 
ATOM 2982 O O   . ILE C 2 155 ? 129.133 147.553 151.481 1.00 85.30  ? 155 ILE C O   1 
ATOM 2983 C CB  . ILE C 2 155 ? 127.246 148.269 153.618 1.00 74.35  ? 155 ILE C CB  1 
ATOM 2984 C CG1 . ILE C 2 155 ? 126.613 149.144 152.538 1.00 71.32  ? 155 ILE C CG1 1 
ATOM 2985 C CG2 . ILE C 2 155 ? 128.537 148.879 154.145 1.00 82.10  ? 155 ILE C CG2 1 
ATOM 2986 C CD1 . ILE C 2 155 ? 126.403 150.570 152.961 1.00 84.34  ? 155 ILE C CD1 1 
ATOM 2987 N N   . ALA C 2 156 ? 127.565 146.109 150.774 1.00 81.05  ? 156 ALA C N   1 
ATOM 2988 C CA  . ALA C 2 156 ? 128.074 146.019 149.417 1.00 77.60  ? 156 ALA C CA  1 
ATOM 2989 C C   . ALA C 2 156 ? 127.156 146.761 148.457 1.00 78.05  ? 156 ALA C C   1 
ATOM 2990 O O   . ALA C 2 156 ? 126.039 147.151 148.801 1.00 81.38  ? 156 ALA C O   1 
ATOM 2991 C CB  . ALA C 2 156 ? 128.213 144.559 148.988 1.00 70.46  ? 156 ALA C CB  1 
ATOM 2992 N N   . ARG C 2 157 ? 127.651 146.965 147.237 1.00 73.94  ? 157 ARG C N   1 
ATOM 2993 C CA  . ARG C 2 157 ? 126.840 147.625 146.223 1.00 78.55  ? 157 ARG C CA  1 
ATOM 2994 C C   . ARG C 2 157 ? 125.708 146.730 145.740 1.00 75.43  ? 157 ARG C C   1 
ATOM 2995 O O   . ARG C 2 157 ? 124.623 147.228 145.424 1.00 79.11  ? 157 ARG C O   1 
ATOM 2996 C CB  . ARG C 2 157 ? 127.716 148.059 145.050 1.00 82.69  ? 157 ARG C CB  1 
ATOM 2997 C CG  . ARG C 2 157 ? 128.820 149.030 145.430 1.00 89.41  ? 157 ARG C CG  1 
ATOM 2998 C CD  . ARG C 2 157 ? 129.663 149.399 144.222 1.00 108.05 ? 157 ARG C CD  1 
ATOM 2999 N NE  . ARG C 2 157 ? 130.742 150.318 144.563 1.00 122.33 ? 157 ARG C NE  1 
ATOM 3000 C CZ  . ARG C 2 157 ? 131.667 150.737 143.710 1.00 121.28 ? 157 ARG C CZ  1 
ATOM 3001 N NH1 . ARG C 2 157 ? 131.675 150.337 142.449 1.00 114.53 ? 157 ARG C NH1 1 
ATOM 3002 N NH2 . ARG C 2 157 ? 132.606 151.578 144.132 1.00 124.68 ? 157 ARG C NH2 1 
ATOM 3003 N N   . ASN C 2 158 ? 125.934 145.421 145.671 1.00 66.84  ? 158 ASN C N   1 
ATOM 3004 C CA  . ASN C 2 158 ? 124.925 144.475 145.218 1.00 67.48  ? 158 ASN C CA  1 
ATOM 3005 C C   . ASN C 2 158 ? 124.761 143.356 146.235 1.00 61.19  ? 158 ASN C C   1 
ATOM 3006 O O   . ASN C 2 158 ? 125.748 142.821 146.750 1.00 66.92  ? 158 ASN C O   1 
ATOM 3007 C CB  . ASN C 2 158 ? 125.291 143.888 143.857 1.00 77.05  ? 158 ASN C CB  1 
ATOM 3008 C CG  . ASN C 2 158 ? 125.459 144.951 142.795 1.00 85.92  ? 158 ASN C CG  1 
ATOM 3009 O OD1 . ASN C 2 158 ? 124.488 145.391 142.180 1.00 85.94  ? 158 ASN C OD1 1 
ATOM 3010 N ND2 . ASN C 2 158 ? 126.698 145.369 142.569 1.00 86.78  ? 158 ASN C ND2 1 
ATOM 3011 N N   . ILE C 2 159 ? 123.506 142.997 146.504 1.00 54.81  ? 159 ILE C N   1 
ATOM 3012 C CA  . ILE C 2 159 ? 123.153 141.978 147.486 1.00 48.03  ? 159 ILE C CA  1 
ATOM 3013 C C   . ILE C 2 159 ? 122.071 141.102 146.870 1.00 54.69  ? 159 ILE C C   1 
ATOM 3014 O O   . ILE C 2 159 ? 120.914 141.520 146.779 1.00 61.10  ? 159 ILE C O   1 
ATOM 3015 C CB  . ILE C 2 159 ? 122.656 142.586 148.803 1.00 41.01  ? 159 ILE C CB  1 
ATOM 3016 C CG1 . ILE C 2 159 ? 123.754 143.424 149.455 1.00 45.90  ? 159 ILE C CG1 1 
ATOM 3017 C CG2 . ILE C 2 159 ? 122.187 141.499 149.740 1.00 41.58  ? 159 ILE C CG2 1 
ATOM 3018 C CD1 . ILE C 2 159 ? 123.340 144.060 150.749 1.00 49.92  ? 159 ILE C CD1 1 
ATOM 3019 N N   . TYR C 2 160 ? 122.435 139.891 146.464 1.00 56.58  ? 160 TYR C N   1 
ATOM 3020 C CA  . TYR C 2 160 ? 121.517 138.974 145.802 1.00 52.19  ? 160 TYR C CA  1 
ATOM 3021 C C   . TYR C 2 160 ? 120.828 138.106 146.847 1.00 52.34  ? 160 TYR C C   1 
ATOM 3022 O O   . TYR C 2 160 ? 121.498 137.488 147.685 1.00 60.70  ? 160 TYR C O   1 
ATOM 3023 C CB  . TYR C 2 160 ? 122.262 138.100 144.794 1.00 53.97  ? 160 TYR C CB  1 
ATOM 3024 C CG  . TYR C 2 160 ? 123.041 138.881 143.766 1.00 61.41  ? 160 TYR C CG  1 
ATOM 3025 C CD1 . TYR C 2 160 ? 124.297 139.384 144.056 1.00 63.22  ? 160 TYR C CD1 1 
ATOM 3026 C CD2 . TYR C 2 160 ? 122.521 139.111 142.504 1.00 71.28  ? 160 TYR C CD2 1 
ATOM 3027 C CE1 . TYR C 2 160 ? 125.010 140.100 143.125 1.00 71.81  ? 160 TYR C CE1 1 
ATOM 3028 C CE2 . TYR C 2 160 ? 123.227 139.826 141.565 1.00 78.50  ? 160 TYR C CE2 1 
ATOM 3029 C CZ  . TYR C 2 160 ? 124.472 140.317 141.881 1.00 82.50  ? 160 TYR C CZ  1 
ATOM 3030 O OH  . TYR C 2 160 ? 125.187 141.031 140.948 1.00 91.42  ? 160 TYR C OH  1 
ATOM 3031 N N   . ILE C 2 161 ? 119.499 138.056 146.791 1.00 50.25  ? 161 ILE C N   1 
ATOM 3032 C CA  . ILE C 2 161 ? 118.688 137.210 147.655 1.00 51.03  ? 161 ILE C CA  1 
ATOM 3033 C C   . ILE C 2 161 ? 117.788 136.359 146.773 1.00 57.04  ? 161 ILE C C   1 
ATOM 3034 O O   . ILE C 2 161 ? 117.150 136.872 145.844 1.00 64.98  ? 161 ILE C O   1 
ATOM 3035 C CB  . ILE C 2 161 ? 117.848 138.037 148.643 1.00 47.31  ? 161 ILE C CB  1 
ATOM 3036 C CG1 . ILE C 2 161 ? 118.746 138.883 149.539 1.00 42.01  ? 161 ILE C CG1 1 
ATOM 3037 C CG2 . ILE C 2 161 ? 116.979 137.129 149.485 1.00 47.03  ? 161 ILE C CG2 1 
ATOM 3038 C CD1 . ILE C 2 161 ? 119.281 138.148 150.730 1.00 46.50  ? 161 ILE C CD1 1 
ATOM 3039 N N   . LYS C 2 162 ? 117.742 135.066 147.057 1.00 56.76  ? 162 LYS C N   1 
ATOM 3040 C CA  . LYS C 2 162 ? 116.903 134.125 146.330 1.00 64.28  ? 162 LYS C CA  1 
ATOM 3041 C C   . LYS C 2 162 ? 115.859 133.589 147.299 1.00 75.42  ? 162 LYS C C   1 
ATOM 3042 O O   . LYS C 2 162 ? 116.182 132.821 148.209 1.00 82.77  ? 162 LYS C O   1 
ATOM 3043 C CB  . LYS C 2 162 ? 117.744 133.006 145.722 1.00 65.11  ? 162 LYS C CB  1 
ATOM 3044 C CG  . LYS C 2 162 ? 117.696 132.965 144.207 1.00 69.80  ? 162 LYS C CG  1 
ATOM 3045 C CD  . LYS C 2 162 ? 118.790 132.095 143.619 1.00 71.76  ? 162 LYS C CD  1 
ATOM 3046 C CE  . LYS C 2 162 ? 120.049 132.897 143.355 1.00 68.95  ? 162 LYS C CE  1 
ATOM 3047 N NZ  . LYS C 2 162 ? 121.089 132.082 142.664 1.00 68.83  ? 162 LYS C NZ  1 
ATOM 3048 N N   . VAL C 2 163 ? 114.611 133.998 147.099 1.00 73.06  ? 163 VAL C N   1 
ATOM 3049 C CA  . VAL C 2 163 ? 113.542 133.663 148.027 1.00 73.87  ? 163 VAL C CA  1 
ATOM 3050 C C   . VAL C 2 163 ? 113.023 132.258 147.745 1.00 80.81  ? 163 VAL C C   1 
ATOM 3051 O O   . VAL C 2 163 ? 113.297 131.656 146.706 1.00 81.10  ? 163 VAL C O   1 
ATOM 3052 C CB  . VAL C 2 163 ? 112.413 134.702 147.946 1.00 82.03  ? 163 VAL C CB  1 
ATOM 3053 C CG1 . VAL C 2 163 ? 112.956 136.086 148.237 1.00 78.77  ? 163 VAL C CG1 1 
ATOM 3054 C CG2 . VAL C 2 163 ? 111.781 134.665 146.577 1.00 93.63  ? 163 VAL C CG2 1 
ATOM 3055 N N   . GLY C 2 164 ? 112.256 131.737 148.687 1.00 83.78  ? 164 GLY C N   1 
ATOM 3056 C CA  . GLY C 2 164 ? 111.711 130.394 148.595 1.00 91.39  ? 164 GLY C CA  1 
ATOM 3057 C C   . GLY C 2 164 ? 112.434 129.470 149.556 1.00 94.08  ? 164 GLY C C   1 
ATOM 3058 O O   . GLY C 2 164 ? 113.644 129.595 149.780 1.00 94.64  ? 164 GLY C O   1 
ATOM 3059 N N   . GLU C 2 165 ? 111.692 128.527 150.127 1.00 95.78  ? 165 GLU C N   1 
ATOM 3060 C CA  . GLU C 2 165 ? 112.245 127.610 151.113 1.00 98.43  ? 165 GLU C CA  1 
ATOM 3061 C C   . GLU C 2 165 ? 112.909 126.427 150.423 1.00 101.97 ? 165 GLU C C   1 
ATOM 3062 O O   . GLU C 2 165 ? 112.320 125.811 149.531 1.00 106.01 ? 165 GLU C O   1 
ATOM 3063 C CB  . GLU C 2 165 ? 111.159 127.106 152.063 1.00 102.85 ? 165 GLU C CB  1 
ATOM 3064 C CG  . GLU C 2 165 ? 110.368 128.192 152.769 1.00 108.02 ? 165 GLU C CG  1 
ATOM 3065 C CD  . GLU C 2 165 ? 109.109 128.574 152.020 1.00 114.62 ? 165 GLU C CD  1 
ATOM 3066 O OE1 . GLU C 2 165 ? 109.136 128.572 150.771 1.00 113.96 ? 165 GLU C OE1 1 
ATOM 3067 O OE2 . GLU C 2 165 ? 108.091 128.872 152.679 1.00 116.48 ? 165 GLU C OE2 1 
ATOM 3068 N N   . ASP C 2 166 ? 114.129 126.111 150.844 1.00 102.13 ? 166 ASP C N   1 
ATOM 3069 C CA  . ASP C 2 166 ? 114.818 124.895 150.436 1.00 103.07 ? 166 ASP C CA  1 
ATOM 3070 C C   . ASP C 2 166 ? 114.791 123.919 151.601 1.00 108.12 ? 166 ASP C C   1 
ATOM 3071 O O   . ASP C 2 166 ? 115.226 124.257 152.707 1.00 110.12 ? 166 ASP C O   1 
ATOM 3072 C CB  . ASP C 2 166 ? 116.263 125.184 150.025 1.00 103.73 ? 166 ASP C CB  1 
ATOM 3073 C CG  . ASP C 2 166 ? 116.363 126.252 148.956 1.00 103.71 ? 166 ASP C CG  1 
ATOM 3074 O OD1 . ASP C 2 166 ? 115.978 127.407 149.231 1.00 99.58  ? 166 ASP C OD1 1 
ATOM 3075 O OD2 . ASP C 2 166 ? 116.835 125.938 147.843 1.00 108.50 ? 166 ASP C OD2 1 
ATOM 3076 N N   . GLN C 2 167 ? 114.290 122.712 151.356 1.00 114.44 ? 167 GLN C N   1 
ATOM 3077 C CA  . GLN C 2 167 ? 114.101 121.751 152.434 1.00 120.24 ? 167 GLN C CA  1 
ATOM 3078 C C   . GLN C 2 167 ? 115.402 121.116 152.908 1.00 116.81 ? 167 GLN C C   1 
ATOM 3079 O O   . GLN C 2 167 ? 115.389 120.403 153.916 1.00 112.64 ? 167 GLN C O   1 
ATOM 3080 C CB  . GLN C 2 167 ? 113.114 120.665 152.001 1.00 126.63 ? 167 GLN C CB  1 
ATOM 3081 C CG  . GLN C 2 167 ? 111.706 121.187 151.765 1.00 128.13 ? 167 GLN C CG  1 
ATOM 3082 C CD  . GLN C 2 167 ? 110.713 120.082 151.474 1.00 139.43 ? 167 GLN C CD  1 
ATOM 3083 O OE1 . GLN C 2 167 ? 111.065 118.903 151.460 1.00 145.12 ? 167 GLN C OE1 1 
ATOM 3084 N NE2 . GLN C 2 167 ? 109.462 120.458 151.240 1.00 141.17 ? 167 GLN C NE2 1 
ATOM 3085 N N   . VAL C 2 168 ? 116.518 121.351 152.216 1.00 116.32 ? 168 VAL C N   1 
ATOM 3086 C CA  . VAL C 2 168 ? 117.801 120.856 152.701 1.00 116.12 ? 168 VAL C CA  1 
ATOM 3087 C C   . VAL C 2 168 ? 118.353 121.719 153.826 1.00 113.23 ? 168 VAL C C   1 
ATOM 3088 O O   . VAL C 2 168 ? 119.262 121.283 154.543 1.00 108.87 ? 168 VAL C O   1 
ATOM 3089 C CB  . VAL C 2 168 ? 118.828 120.771 151.560 1.00 113.56 ? 168 VAL C CB  1 
ATOM 3090 C CG1 . VAL C 2 168 ? 118.417 119.707 150.556 1.00 112.97 ? 168 VAL C CG1 1 
ATOM 3091 C CG2 . VAL C 2 168 ? 118.979 122.123 150.877 1.00 108.66 ? 168 VAL C CG2 1 
ATOM 3092 N N   . PHE C 2 169 ? 117.831 122.930 153.998 1.00 111.13 ? 169 PHE C N   1 
ATOM 3093 C CA  . PHE C 2 169 ? 118.296 123.812 155.054 1.00 107.48 ? 169 PHE C CA  1 
ATOM 3094 C C   . PHE C 2 169 ? 117.844 123.300 156.423 1.00 113.56 ? 169 PHE C C   1 
ATOM 3095 O O   . PHE C 2 169 ? 116.843 122.587 156.530 1.00 115.92 ? 169 PHE C O   1 
ATOM 3096 C CB  . PHE C 2 169 ? 117.773 125.225 154.823 1.00 100.41 ? 169 PHE C CB  1 
ATOM 3097 C CG  . PHE C 2 169 ? 118.517 125.975 153.763 1.00 97.67  ? 169 PHE C CG  1 
ATOM 3098 C CD1 . PHE C 2 169 ? 119.896 125.911 153.695 1.00 92.16  ? 169 PHE C CD1 1 
ATOM 3099 C CD2 . PHE C 2 169 ? 117.841 126.736 152.830 1.00 95.90  ? 169 PHE C CD2 1 
ATOM 3100 C CE1 . PHE C 2 169 ? 120.587 126.602 152.721 1.00 81.21  ? 169 PHE C CE1 1 
ATOM 3101 C CE2 . PHE C 2 169 ? 118.528 127.427 151.853 1.00 88.46  ? 169 PHE C CE2 1 
ATOM 3102 C CZ  . PHE C 2 169 ? 119.902 127.359 151.799 1.00 79.06  ? 169 PHE C CZ  1 
ATOM 3103 N N   . PRO C 2 170 ? 118.570 123.646 157.484 1.00 112.79 ? 170 PRO C N   1 
ATOM 3104 C CA  . PRO C 2 170 ? 118.213 123.165 158.825 1.00 109.51 ? 170 PRO C CA  1 
ATOM 3105 C C   . PRO C 2 170 ? 116.849 123.676 159.252 1.00 108.63 ? 170 PRO C C   1 
ATOM 3106 O O   . PRO C 2 170 ? 116.416 124.753 158.817 1.00 107.13 ? 170 PRO C O   1 
ATOM 3107 C CB  . PRO C 2 170 ? 119.328 123.738 159.714 1.00 104.50 ? 170 PRO C CB  1 
ATOM 3108 C CG  . PRO C 2 170 ? 119.913 124.864 158.923 1.00 104.34 ? 170 PRO C CG  1 
ATOM 3109 C CD  . PRO C 2 170 ? 119.813 124.433 157.498 1.00 106.02 ? 170 PRO C CD  1 
ATOM 3110 N N   . PRO C 2 171 ? 116.135 122.919 160.090 1.00 112.28 ? 171 PRO C N   1 
ATOM 3111 C CA  . PRO C 2 171 ? 114.785 123.345 160.498 1.00 112.14 ? 171 PRO C CA  1 
ATOM 3112 C C   . PRO C 2 171 ? 114.753 124.664 161.249 1.00 109.45 ? 171 PRO C C   1 
ATOM 3113 O O   . PRO C 2 171 ? 113.768 125.404 161.136 1.00 108.85 ? 171 PRO C O   1 
ATOM 3114 C CB  . PRO C 2 171 ? 114.309 122.183 161.380 1.00 114.40 ? 171 PRO C CB  1 
ATOM 3115 C CG  . PRO C 2 171 ? 115.565 121.553 161.881 1.00 114.32 ? 171 PRO C CG  1 
ATOM 3116 C CD  . PRO C 2 171 ? 116.552 121.676 160.760 1.00 114.29 ? 171 PRO C CD  1 
ATOM 3117 N N   . THR C 2 172 ? 115.788 124.978 162.021 1.00 108.52 ? 172 THR C N   1 
ATOM 3118 C CA  . THR C 2 172 ? 115.832 126.204 162.802 1.00 108.55 ? 172 THR C CA  1 
ATOM 3119 C C   . THR C 2 172 ? 117.143 126.928 162.532 1.00 109.47 ? 172 THR C C   1 
ATOM 3120 O O   . THR C 2 172 ? 118.191 126.308 162.334 1.00 104.71 ? 172 THR C O   1 
ATOM 3121 C CB  . THR C 2 172 ? 115.680 125.920 164.303 1.00 106.67 ? 172 THR C CB  1 
ATOM 3122 O OG1 . THR C 2 172 ? 114.558 125.054 164.513 1.00 105.08 ? 172 THR C OG1 1 
ATOM 3123 C CG2 . THR C 2 172 ? 115.457 127.210 165.077 1.00 101.27 ? 172 THR C CG2 1 
ATOM 3124 N N   . CYS C 2 173 ? 117.070 128.255 162.518 1.00 108.20 ? 173 CYS C N   1 
ATOM 3125 C CA  . CYS C 2 173 ? 118.246 129.067 162.245 1.00 103.27 ? 173 CYS C CA  1 
ATOM 3126 C C   . CYS C 2 173 ? 119.265 128.935 163.368 1.00 101.08 ? 173 CYS C C   1 
ATOM 3127 O O   . CYS C 2 173 ? 118.915 128.924 164.551 1.00 105.81 ? 173 CYS C O   1 
ATOM 3128 C CB  . CYS C 2 173 ? 117.848 130.531 162.075 1.00 98.37  ? 173 CYS C CB  1 
ATOM 3129 S SG  . CYS C 2 173 ? 118.347 131.277 160.516 1.00 103.97 ? 173 CYS C SG  1 
ATOM 3130 N N   . ASN C 2 174 ? 120.537 128.835 162.989 1.00 98.94  ? 174 ASN C N   1 
ATOM 3131 C CA  . ASN C 2 174 ? 121.635 128.833 163.954 1.00 99.80  ? 174 ASN C CA  1 
ATOM 3132 C C   . ASN C 2 174 ? 122.799 129.569 163.301 1.00 92.83  ? 174 ASN C C   1 
ATOM 3133 O O   . ASN C 2 174 ? 123.490 129.008 162.446 1.00 89.32  ? 174 ASN C O   1 
ATOM 3134 C CB  . ASN C 2 174 ? 122.019 127.418 164.364 1.00 98.65  ? 174 ASN C CB  1 
ATOM 3135 C CG  . ASN C 2 174 ? 121.168 126.890 165.504 1.00 101.79 ? 174 ASN C CG  1 
ATOM 3136 O OD1 . ASN C 2 174 ? 120.734 127.648 166.371 1.00 101.83 ? 174 ASN C OD1 1 
ATOM 3137 N ND2 . ASN C 2 174 ? 120.926 125.585 165.508 1.00 104.94 ? 174 ASN C ND2 1 
ATOM 3138 N N   . ILE C 2 175 ? 123.005 130.822 163.709 1.00 88.46  ? 175 ILE C N   1 
ATOM 3139 C CA  . ILE C 2 175 ? 123.993 131.668 163.055 1.00 80.50  ? 175 ILE C CA  1 
ATOM 3140 C C   . ILE C 2 175 ? 125.392 131.111 163.266 1.00 79.75  ? 175 ILE C C   1 
ATOM 3141 O O   . ILE C 2 175 ? 125.779 130.744 164.383 1.00 82.77  ? 175 ILE C O   1 
ATOM 3142 C CB  . ILE C 2 175 ? 123.885 133.107 163.583 1.00 78.11  ? 175 ILE C CB  1 
ATOM 3143 C CG1 . ILE C 2 175 ? 122.552 133.718 163.170 1.00 76.59  ? 175 ILE C CG1 1 
ATOM 3144 C CG2 . ILE C 2 175 ? 125.034 133.957 163.080 1.00 73.14  ? 175 ILE C CG2 1 
ATOM 3145 C CD1 . ILE C 2 175 ? 122.334 135.084 163.746 1.00 87.95  ? 175 ILE C CD1 1 
ATOM 3146 N N   . GLY C 2 176 ? 126.156 131.039 162.181 1.00 75.44  ? 176 GLY C N   1 
ATOM 3147 C CA  . GLY C 2 176 ? 127.545 130.637 162.244 1.00 73.39  ? 176 GLY C CA  1 
ATOM 3148 C C   . GLY C 2 176 ? 128.394 131.463 161.303 1.00 69.19  ? 176 GLY C C   1 
ATOM 3149 O O   . GLY C 2 176 ? 127.917 131.891 160.251 1.00 68.98  ? 176 GLY C O   1 
ATOM 3150 N N   . LYS C 2 177 ? 129.651 131.710 161.673 1.00 71.29  ? 177 LYS C N   1 
ATOM 3151 C CA  . LYS C 2 177 ? 130.522 132.496 160.806 1.00 72.66  ? 177 LYS C CA  1 
ATOM 3152 C C   . LYS C 2 177 ? 130.825 131.755 159.513 1.00 70.07  ? 177 LYS C C   1 
ATOM 3153 O O   . LYS C 2 177 ? 130.900 132.366 158.441 1.00 68.53  ? 177 LYS C O   1 
ATOM 3154 C CB  . LYS C 2 177 ? 131.816 132.848 161.536 1.00 77.67  ? 177 LYS C CB  1 
ATOM 3155 C CG  . LYS C 2 177 ? 131.613 133.598 162.839 1.00 81.50  ? 177 LYS C CG  1 
ATOM 3156 C CD  . LYS C 2 177 ? 132.908 134.238 163.308 1.00 89.42  ? 177 LYS C CD  1 
ATOM 3157 C CE  . LYS C 2 177 ? 134.048 133.234 163.316 1.00 93.53  ? 177 LYS C CE  1 
ATOM 3158 N NZ  . LYS C 2 177 ? 133.746 132.056 164.172 1.00 92.75  ? 177 LYS C NZ  1 
ATOM 3159 N N   . ASN C 2 178 ? 131.007 130.440 159.591 1.00 72.20  ? 178 ASN C N   1 
ATOM 3160 C CA  . ASN C 2 178 ? 131.352 129.636 158.421 1.00 71.69  ? 178 ASN C CA  1 
ATOM 3161 C C   . ASN C 2 178 ? 130.095 129.048 157.779 1.00 72.38  ? 178 ASN C C   1 
ATOM 3162 O O   . ASN C 2 178 ? 129.905 127.836 157.698 1.00 69.93  ? 178 ASN C O   1 
ATOM 3163 C CB  . ASN C 2 178 ? 132.341 128.542 158.805 1.00 70.76  ? 178 ASN C CB  1 
ATOM 3164 C CG  . ASN C 2 178 ? 133.619 129.097 159.398 1.00 82.86  ? 178 ASN C CG  1 
ATOM 3165 O OD1 . ASN C 2 178 ? 134.466 129.634 158.684 1.00 87.26  ? 178 ASN C OD1 1 
ATOM 3166 N ND2 . ASN C 2 178 ? 133.770 128.963 160.710 1.00 88.19  ? 178 ASN C ND2 1 
ATOM 3167 N N   . PHE C 2 179 ? 129.222 129.944 157.325 1.00 69.03  ? 179 PHE C N   1 
ATOM 3168 C CA  . PHE C 2 179 ? 128.060 129.558 156.541 1.00 60.64  ? 179 PHE C CA  1 
ATOM 3169 C C   . PHE C 2 179 ? 127.928 130.489 155.349 1.00 58.20  ? 179 PHE C C   1 
ATOM 3170 O O   . PHE C 2 179 ? 128.092 131.705 155.478 1.00 57.23  ? 179 PHE C O   1 
ATOM 3171 C CB  . PHE C 2 179 ? 126.770 129.589 157.362 1.00 58.14  ? 179 PHE C CB  1 
ATOM 3172 C CG  . PHE C 2 179 ? 125.549 129.206 156.577 1.00 59.09  ? 179 PHE C CG  1 
ATOM 3173 C CD1 . PHE C 2 179 ? 125.220 127.879 156.392 1.00 59.34  ? 179 PHE C CD1 1 
ATOM 3174 C CD2 . PHE C 2 179 ? 124.733 130.172 156.025 1.00 60.19  ? 179 PHE C CD2 1 
ATOM 3175 C CE1 . PHE C 2 179 ? 124.101 127.524 155.671 1.00 59.68  ? 179 PHE C CE1 1 
ATOM 3176 C CE2 . PHE C 2 179 ? 123.615 129.819 155.305 1.00 57.69  ? 179 PHE C CE2 1 
ATOM 3177 C CZ  . PHE C 2 179 ? 123.301 128.494 155.129 1.00 58.84  ? 179 PHE C CZ  1 
ATOM 3178 N N   . LEU C 2 180 ? 127.630 129.908 154.192 1.00 55.78  ? 180 LEU C N   1 
ATOM 3179 C CA  . LEU C 2 180 ? 127.463 130.678 152.964 1.00 49.54  ? 180 LEU C CA  1 
ATOM 3180 C C   . LEU C 2 180 ? 126.646 129.843 151.997 1.00 46.29  ? 180 LEU C C   1 
ATOM 3181 O O   . LEU C 2 180 ? 127.132 128.825 151.499 1.00 44.74  ? 180 LEU C O   1 
ATOM 3182 C CB  . LEU C 2 180 ? 128.817 131.044 152.363 1.00 47.03  ? 180 LEU C CB  1 
ATOM 3183 C CG  . LEU C 2 180 ? 128.863 131.703 150.987 1.00 45.82  ? 180 LEU C CG  1 
ATOM 3184 C CD1 . LEU C 2 180 ? 127.885 132.846 150.911 1.00 49.95  ? 180 LEU C CD1 1 
ATOM 3185 C CD2 . LEU C 2 180 ? 130.258 132.206 150.703 1.00 47.92  ? 180 LEU C CD2 1 
ATOM 3186 N N   . SER C 2 181 ? 125.411 130.260 151.744 1.00 46.96  ? 181 SER C N   1 
ATOM 3187 C CA  . SER C 2 181 ? 124.560 129.643 150.739 1.00 45.95  ? 181 SER C CA  1 
ATOM 3188 C C   . SER C 2 181 ? 124.441 130.603 149.570 1.00 46.01  ? 181 SER C C   1 
ATOM 3189 O O   . SER C 2 181 ? 124.314 131.813 149.772 1.00 49.13  ? 181 SER C O   1 
ATOM 3190 C CB  . SER C 2 181 ? 123.178 129.315 151.298 1.00 51.04  ? 181 SER C CB  1 
ATOM 3191 O OG  . SER C 2 181 ? 122.376 128.694 150.312 1.00 47.71  ? 181 SER C OG  1 
ATOM 3192 N N   . LEU C 2 182 ? 124.488 130.063 148.353 1.00 45.48  ? 182 LEU C N   1 
ATOM 3193 C CA  . LEU C 2 182 ? 124.543 130.909 147.169 1.00 43.19  ? 182 LEU C CA  1 
ATOM 3194 C C   . LEU C 2 182 ? 123.278 131.726 146.970 1.00 46.67  ? 182 LEU C C   1 
ATOM 3195 O O   . LEU C 2 182 ? 123.285 132.654 146.155 1.00 44.41  ? 182 LEU C O   1 
ATOM 3196 C CB  . LEU C 2 182 ? 124.819 130.057 145.935 1.00 32.15  ? 182 LEU C CB  1 
ATOM 3197 C CG  . LEU C 2 182 ? 123.758 129.013 145.616 1.00 35.66  ? 182 LEU C CG  1 
ATOM 3198 C CD1 . LEU C 2 182 ? 122.575 129.633 144.907 1.00 42.24  ? 182 LEU C CD1 1 
ATOM 3199 C CD2 . LEU C 2 182 ? 124.363 127.920 144.781 1.00 48.00  ? 182 LEU C CD2 1 
ATOM 3200 N N   . ASN C 2 183 ? 122.198 131.404 147.680 1.00 46.65  ? 183 ASN C N   1 
ATOM 3201 C CA  . ASN C 2 183 ? 121.004 132.233 147.603 1.00 47.42  ? 183 ASN C CA  1 
ATOM 3202 C C   . ASN C 2 183 ? 121.282 133.639 148.115 1.00 46.97  ? 183 ASN C C   1 
ATOM 3203 O O   . ASN C 2 183 ? 121.250 134.606 147.348 1.00 58.29  ? 183 ASN C O   1 
ATOM 3204 C CB  . ASN C 2 183 ? 119.868 131.583 148.387 1.00 47.27  ? 183 ASN C CB  1 
ATOM 3205 C CG  . ASN C 2 183 ? 119.527 130.206 147.875 1.00 52.41  ? 183 ASN C CG  1 
ATOM 3206 O OD1 . ASN C 2 183 ? 119.730 129.903 146.704 1.00 54.86  ? 183 ASN C OD1 1 
ATOM 3207 N ND2 . ASN C 2 183 ? 119.007 129.361 148.751 1.00 59.47  ? 183 ASN C ND2 1 
ATOM 3208 N N   . TYR C 2 184 ? 121.597 133.770 149.397 1.00 39.01  ? 184 TYR C N   1 
ATOM 3209 C CA  . TYR C 2 184 ? 121.769 135.066 150.045 1.00 38.31  ? 184 TYR C CA  1 
ATOM 3210 C C   . TYR C 2 184 ? 123.255 135.383 150.119 1.00 44.13  ? 184 TYR C C   1 
ATOM 3211 O O   . TYR C 2 184 ? 123.978 134.799 150.928 1.00 50.99  ? 184 TYR C O   1 
ATOM 3212 C CB  . TYR C 2 184 ? 121.144 135.055 151.432 1.00 42.09  ? 184 TYR C CB  1 
ATOM 3213 C CG  . TYR C 2 184 ? 120.160 133.935 151.625 1.00 44.94  ? 184 TYR C CG  1 
ATOM 3214 C CD1 . TYR C 2 184 ? 118.896 134.000 151.074 1.00 52.42  ? 184 TYR C CD1 1 
ATOM 3215 C CD2 . TYR C 2 184 ? 120.497 132.811 152.353 1.00 48.39  ? 184 TYR C CD2 1 
ATOM 3216 C CE1 . TYR C 2 184 ? 117.996 132.978 151.238 1.00 56.20  ? 184 TYR C CE1 1 
ATOM 3217 C CE2 . TYR C 2 184 ? 119.602 131.784 152.525 1.00 57.25  ? 184 TYR C CE2 1 
ATOM 3218 C CZ  . TYR C 2 184 ? 118.351 131.872 151.964 1.00 60.46  ? 184 TYR C CZ  1 
ATOM 3219 O OH  . TYR C 2 184 ? 117.445 130.850 152.130 1.00 71.47  ? 184 TYR C OH  1 
ATOM 3220 N N   . LEU C 2 185 ? 123.714 136.311 149.282 1.00 46.63  ? 185 LEU C N   1 
ATOM 3221 C CA  . LEU C 2 185 ? 125.108 136.725 149.361 1.00 49.77  ? 185 LEU C CA  1 
ATOM 3222 C C   . LEU C 2 185 ? 125.256 138.131 148.805 1.00 45.40  ? 185 LEU C C   1 
ATOM 3223 O O   . LEU C 2 185 ? 124.316 138.705 148.262 1.00 48.24  ? 185 LEU C O   1 
ATOM 3224 C CB  . LEU C 2 185 ? 126.043 135.744 148.639 1.00 48.77  ? 185 LEU C CB  1 
ATOM 3225 C CG  . LEU C 2 185 ? 125.604 135.004 147.378 1.00 44.72  ? 185 LEU C CG  1 
ATOM 3226 C CD1 . LEU C 2 185 ? 125.514 135.936 146.193 1.00 51.35  ? 185 LEU C CD1 1 
ATOM 3227 C CD2 . LEU C 2 185 ? 126.575 133.885 147.093 1.00 40.51  ? 185 LEU C CD2 1 
ATOM 3228 N N   . ALA C 2 186 ? 126.438 138.694 148.996 1.00 48.00  ? 186 ALA C N   1 
ATOM 3229 C CA  . ALA C 2 186 ? 126.772 140.030 148.536 1.00 52.50  ? 186 ALA C CA  1 
ATOM 3230 C C   . ALA C 2 186 ? 127.854 139.941 147.468 1.00 60.18  ? 186 ALA C C   1 
ATOM 3231 O O   . ALA C 2 186 ? 128.460 138.893 147.256 1.00 64.38  ? 186 ALA C O   1 
ATOM 3232 C CB  . ALA C 2 186 ? 127.222 140.901 149.707 1.00 53.10  ? 186 ALA C CB  1 
ATOM 3233 N N   . GLU C 2 187 ? 128.104 141.058 146.789 1.00 63.76  ? 187 GLU C N   1 
ATOM 3234 C CA  . GLU C 2 187 ? 129.113 141.063 145.731 1.00 63.94  ? 187 GLU C CA  1 
ATOM 3235 C C   . GLU C 2 187 ? 130.131 142.152 146.051 1.00 64.93  ? 187 GLU C C   1 
ATOM 3236 O O   . GLU C 2 187 ? 129.790 143.337 146.059 1.00 74.16  ? 187 GLU C O   1 
ATOM 3237 C CB  . GLU C 2 187 ? 128.477 141.280 144.367 1.00 69.75  ? 187 GLU C CB  1 
ATOM 3238 C CG  . GLU C 2 187 ? 129.477 141.349 143.229 1.00 80.79  ? 187 GLU C CG  1 
ATOM 3239 C CD  . GLU C 2 187 ? 128.829 141.695 141.907 1.00 91.00  ? 187 GLU C CD  1 
ATOM 3240 O OE1 . GLU C 2 187 ? 127.582 141.685 141.835 1.00 86.52  ? 187 GLU C OE1 1 
ATOM 3241 O OE2 . GLU C 2 187 ? 129.566 141.981 140.940 1.00 97.66  ? 187 GLU C OE2 1 
ATOM 3242 N N   . TYR C 2 188 ? 131.374 141.748 146.294 1.00 62.36  ? 188 TYR C N   1 
ATOM 3243 C CA  . TYR C 2 188 ? 132.449 142.668 146.632 1.00 63.85  ? 188 TYR C CA  1 
ATOM 3244 C C   . TYR C 2 188 ? 133.506 142.678 145.538 1.00 70.87  ? 188 TYR C C   1 
ATOM 3245 O O   . TYR C 2 188 ? 133.869 141.627 145.000 1.00 76.22  ? 188 TYR C O   1 
ATOM 3246 C CB  . TYR C 2 188 ? 133.103 142.290 147.962 1.00 65.97  ? 188 TYR C CB  1 
ATOM 3247 C CG  . TYR C 2 188 ? 132.124 142.059 149.080 1.00 66.05  ? 188 TYR C CG  1 
ATOM 3248 C CD1 . TYR C 2 188 ? 131.654 143.113 149.846 1.00 67.04  ? 188 TYR C CD1 1 
ATOM 3249 C CD2 . TYR C 2 188 ? 131.670 140.787 149.372 1.00 67.09  ? 188 TYR C CD2 1 
ATOM 3250 C CE1 . TYR C 2 188 ? 130.757 142.903 150.868 1.00 69.72  ? 188 TYR C CE1 1 
ATOM 3251 C CE2 . TYR C 2 188 ? 130.775 140.568 150.390 1.00 69.86  ? 188 TYR C CE2 1 
ATOM 3252 C CZ  . TYR C 2 188 ? 130.321 141.627 151.135 1.00 70.16  ? 188 TYR C CZ  1 
ATOM 3253 O OH  . TYR C 2 188 ? 129.428 141.401 152.151 1.00 71.92  ? 188 TYR C OH  1 
ATOM 3254 N N   . LEU C 2 189 ? 134.001 143.870 145.219 1.00 71.27  ? 189 LEU C N   1 
ATOM 3255 C CA  . LEU C 2 189 ? 135.111 144.053 144.293 1.00 73.84  ? 189 LEU C CA  1 
ATOM 3256 C C   . LEU C 2 189 ? 136.308 144.581 145.070 1.00 76.39  ? 189 LEU C C   1 
ATOM 3257 O O   . LEU C 2 189 ? 136.289 145.719 145.548 1.00 77.15  ? 189 LEU C O   1 
ATOM 3258 C CB  . LEU C 2 189 ? 134.741 145.018 143.168 1.00 66.44  ? 189 LEU C CB  1 
ATOM 3259 C CG  . LEU C 2 189 ? 134.161 144.437 141.880 1.00 69.90  ? 189 LEU C CG  1 
ATOM 3260 C CD1 . LEU C 2 189 ? 132.889 143.660 142.151 1.00 70.43  ? 189 LEU C CD1 1 
ATOM 3261 C CD2 . LEU C 2 189 ? 133.905 145.549 140.885 1.00 73.93  ? 189 LEU C CD2 1 
ATOM 3262 N N   . GLN C 2 190 ? 137.349 143.762 145.182 1.00 78.64  ? 190 GLN C N   1 
ATOM 3263 C CA  . GLN C 2 190 ? 138.544 144.113 145.938 1.00 82.80  ? 190 GLN C CA  1 
ATOM 3264 C C   . GLN C 2 190 ? 139.682 144.388 144.968 1.00 81.39  ? 190 GLN C C   1 
ATOM 3265 O O   . GLN C 2 190 ? 140.106 143.468 144.250 1.00 80.79  ? 190 GLN C O   1 
ATOM 3266 C CB  . GLN C 2 190 ? 138.922 142.987 146.901 1.00 87.14  ? 190 GLN C CB  1 
ATOM 3267 C CG  . GLN C 2 190 ? 137.786 142.557 147.813 1.00 91.32  ? 190 GLN C CG  1 
ATOM 3268 C CD  . GLN C 2 190 ? 138.116 141.315 148.612 1.00 100.59 ? 190 GLN C CD  1 
ATOM 3269 O OE1 . GLN C 2 190 ? 139.101 140.629 148.339 1.00 103.59 ? 190 GLN C OE1 1 
ATOM 3270 N NE2 . GLN C 2 190 ? 137.291 141.017 149.609 1.00 96.50  ? 190 GLN C NE2 1 
ATOM 3271 N N   . PRO C 2 191 ? 140.189 145.611 144.881 1.00 81.62  ? 191 PRO C N   1 
ATOM 3272 C CA  . PRO C 2 191 ? 141.302 145.877 143.960 1.00 75.25  ? 191 PRO C CA  1 
ATOM 3273 C C   . PRO C 2 191 ? 142.588 145.201 144.401 1.00 74.79  ? 191 PRO C C   1 
ATOM 3274 O O   . PRO C 2 191 ? 143.206 145.609 145.388 1.00 77.79  ? 191 PRO C O   1 
ATOM 3275 C CB  . PRO C 2 191 ? 141.429 147.405 143.995 1.00 72.09  ? 191 PRO C CB  1 
ATOM 3276 C CG  . PRO C 2 191 ? 140.102 147.888 144.483 1.00 74.51  ? 191 PRO C CG  1 
ATOM 3277 C CD  . PRO C 2 191 ? 139.640 146.849 145.453 1.00 79.34  ? 191 PRO C CD  1 
ATOM 3278 N N   . LYS C 2 192 ? 142.999 144.170 143.670 1.00 73.86  ? 192 LYS C N   1 
ATOM 3279 C CA  . LYS C 2 192 ? 144.190 143.406 144.009 1.00 78.55  ? 192 LYS C CA  1 
ATOM 3280 C C   . LYS C 2 192 ? 145.425 144.063 143.411 1.00 85.57  ? 192 LYS C C   1 
ATOM 3281 O O   . LYS C 2 192 ? 145.384 144.600 142.301 1.00 83.58  ? 192 LYS C O   1 
ATOM 3282 C CB  . LYS C 2 192 ? 144.070 141.968 143.507 1.00 72.93  ? 192 LYS C CB  1 
ATOM 3283 C CG  . LYS C 2 192 ? 142.797 141.267 143.934 1.00 74.56  ? 192 LYS C CG  1 
ATOM 3284 C CD  . LYS C 2 192 ? 142.835 140.878 145.395 1.00 80.43  ? 192 LYS C CD  1 
ATOM 3285 C CE  . LYS C 2 192 ? 143.885 139.814 145.643 1.00 80.43  ? 192 LYS C CE  1 
ATOM 3286 N NZ  . LYS C 2 192 ? 143.891 139.354 147.057 1.00 86.89  ? 192 LYS C NZ  1 
ATOM 3287 N N   . ALA C 2 193 ? 146.524 144.023 144.160 1.00 91.85  ? 193 ALA C N   1 
ATOM 3288 C CA  . ALA C 2 193 ? 147.778 144.575 143.671 1.00 90.71  ? 193 ALA C CA  1 
ATOM 3289 C C   . ALA C 2 193 ? 148.326 143.720 142.537 1.00 88.48  ? 193 ALA C C   1 
ATOM 3290 O O   . ALA C 2 193 ? 148.172 142.496 142.528 1.00 82.19  ? 193 ALA C O   1 
ATOM 3291 C CB  . ALA C 2 193 ? 148.798 144.666 144.805 1.00 84.06  ? 193 ALA C CB  1 
ATOM 3292 N N   . ALA C 2 194 ? 148.968 144.375 141.574 1.00 92.15  ? 194 ALA C N   1 
ATOM 3293 C CA  . ALA C 2 194 ? 149.537 143.679 140.430 1.00 92.23  ? 194 ALA C CA  1 
ATOM 3294 C C   . ALA C 2 194 ? 150.666 144.513 139.848 1.00 96.59  ? 194 ALA C C   1 
ATOM 3295 O O   . ALA C 2 194 ? 150.777 145.714 140.107 1.00 98.13  ? 194 ALA C O   1 
ATOM 3296 C CB  . ALA C 2 194 ? 148.476 143.395 139.363 1.00 86.89  ? 194 ALA C CB  1 
ATOM 3297 N N   . GLU C 2 195 ? 151.509 143.858 139.060 1.00 96.78  ? 195 GLU C N   1 
ATOM 3298 C CA  . GLU C 2 195 ? 152.604 144.513 138.364 1.00 100.73 ? 195 GLU C CA  1 
ATOM 3299 C C   . GLU C 2 195 ? 152.171 144.885 136.952 1.00 96.30  ? 195 GLU C C   1 
ATOM 3300 O O   . GLU C 2 195 ? 151.203 144.348 136.416 1.00 92.24  ? 195 GLU C O   1 
ATOM 3301 C CB  . GLU C 2 195 ? 153.833 143.604 138.310 1.00 106.08 ? 195 GLU C CB  1 
ATOM 3302 C CG  . GLU C 2 195 ? 154.297 143.095 139.661 1.00 110.71 ? 195 GLU C CG  1 
ATOM 3303 C CD  . GLU C 2 195 ? 155.423 142.088 139.543 1.00 118.64 ? 195 GLU C CD  1 
ATOM 3304 O OE1 . GLU C 2 195 ? 155.754 141.695 138.405 1.00 109.24 ? 195 GLU C OE1 1 
ATOM 3305 O OE2 . GLU C 2 195 ? 155.977 141.687 140.588 1.00 127.96 ? 195 GLU C OE2 1 
ATOM 3306 N N   . GLY C 2 196 ? 152.909 145.806 136.347 1.00 99.16  ? 196 GLY C N   1 
ATOM 3307 C CA  . GLY C 2 196 ? 152.610 146.188 134.980 1.00 97.46  ? 196 GLY C CA  1 
ATOM 3308 C C   . GLY C 2 196 ? 153.588 147.227 134.486 1.00 103.33 ? 196 GLY C C   1 
ATOM 3309 O O   . GLY C 2 196 ? 154.421 147.742 135.238 1.00 110.72 ? 196 GLY C O   1 
ATOM 3310 N N   . CYS C 2 197 ? 153.474 147.529 133.196 1.00 101.05 ? 197 CYS C N   1 
ATOM 3311 C CA  . CYS C 2 197 ? 154.299 148.560 132.585 1.00 105.64 ? 197 CYS C CA  1 
ATOM 3312 C C   . CYS C 2 197 ? 153.635 149.049 131.306 1.00 105.21 ? 197 CYS C C   1 
ATOM 3313 O O   . CYS C 2 197 ? 152.997 148.274 130.592 1.00 103.04 ? 197 CYS C O   1 
ATOM 3314 C CB  . CYS C 2 197 ? 155.713 148.046 132.292 1.00 118.35 ? 197 CYS C CB  1 
ATOM 3315 S SG  . CYS C 2 197 ? 155.883 147.055 130.794 1.00 142.58 ? 197 CYS C SG  1 
ATOM 3316 N N   . VAL C 2 198 ? 153.803 150.334 131.018 1.00 109.78 ? 198 VAL C N   1 
ATOM 3317 C CA  . VAL C 2 198 ? 153.223 150.960 129.839 1.00 110.07 ? 198 VAL C CA  1 
ATOM 3318 C C   . VAL C 2 198 ? 154.357 151.449 128.950 1.00 123.09 ? 198 VAL C C   1 
ATOM 3319 O O   . VAL C 2 198 ? 155.269 152.144 129.414 1.00 129.68 ? 198 VAL C O   1 
ATOM 3320 C CB  . VAL C 2 198 ? 152.277 152.108 130.217 1.00 105.41 ? 198 VAL C CB  1 
ATOM 3321 C CG1 . VAL C 2 198 ? 151.000 151.544 130.774 1.00 101.18 ? 198 VAL C CG1 1 
ATOM 3322 C CG2 . VAL C 2 198 ? 152.930 153.027 131.239 1.00 105.47 ? 198 VAL C CG2 1 
ATOM 3323 N N   . LEU C 2 199 ? 154.306 151.076 127.684 1.00 124.42 ? 199 LEU C N   1 
ATOM 3324 C CA  . LEU C 2 199 ? 155.317 151.523 126.736 1.00 133.04 ? 199 LEU C CA  1 
ATOM 3325 C C   . LEU C 2 199 ? 154.999 152.939 126.272 1.00 141.78 ? 199 LEU C C   1 
ATOM 3326 O O   . LEU C 2 199 ? 153.870 153.207 125.849 1.00 139.94 ? 199 LEU C O   1 
ATOM 3327 C CB  . LEU C 2 199 ? 155.391 150.581 125.538 1.00 130.10 ? 199 LEU C CB  1 
ATOM 3328 C CG  . LEU C 2 199 ? 156.237 149.317 125.712 1.00 129.78 ? 199 LEU C CG  1 
ATOM 3329 C CD1 . LEU C 2 199 ? 157.644 149.677 126.167 1.00 128.00 ? 199 LEU C CD1 1 
ATOM 3330 C CD2 . LEU C 2 199 ? 155.589 148.332 126.676 1.00 123.15 ? 199 LEU C CD2 1 
ATOM 3331 N N   . PRO C 2 200 ? 155.953 153.866 126.344 1.00 147.74 ? 200 PRO C N   1 
ATOM 3332 C CA  . PRO C 2 200 ? 155.689 155.237 125.885 1.00 149.39 ? 200 PRO C CA  1 
ATOM 3333 C C   . PRO C 2 200 ? 155.419 155.262 124.389 1.00 151.75 ? 200 PRO C C   1 
ATOM 3334 O O   . PRO C 2 200 ? 156.304 154.992 123.574 1.00 152.35 ? 200 PRO C O   1 
ATOM 3335 C CB  . PRO C 2 200 ? 156.977 155.984 126.249 1.00 150.15 ? 200 PRO C CB  1 
ATOM 3336 C CG  . PRO C 2 200 ? 158.026 154.920 126.306 1.00 149.37 ? 200 PRO C CG  1 
ATOM 3337 C CD  . PRO C 2 200 ? 157.335 153.694 126.821 1.00 144.09 ? 200 PRO C CD  1 
ATOM 3338 N N   . SER C 2 201 ? 154.179 155.584 124.032 1.00 152.72 ? 201 SER C N   1 
ATOM 3339 C CA  . SER C 2 201 ? 153.733 155.550 122.649 1.00 156.81 ? 201 SER C CA  1 
ATOM 3340 C C   . SER C 2 201 ? 152.972 156.822 122.310 1.00 159.51 ? 201 SER C C   1 
ATOM 3341 O O   . SER C 2 201 ? 152.281 157.391 123.161 1.00 158.00 ? 201 SER C O   1 
ATOM 3342 C CB  . SER C 2 201 ? 152.843 154.329 122.384 1.00 155.74 ? 201 SER C CB  1 
ATOM 3343 O OG  . SER C 2 201 ? 152.304 154.365 121.074 1.00 155.02 ? 201 SER C OG  1 
ATOM 3344 N N   . GLN C 2 202 ? 153.109 157.262 121.063 1.00 160.91 ? 202 GLN C N   1 
ATOM 3345 C CA  . GLN C 2 202 ? 152.306 158.357 120.558 1.00 162.66 ? 202 GLN C CA  1 
ATOM 3346 C C   . GLN C 2 202 ? 150.855 157.904 120.408 1.00 165.54 ? 202 GLN C C   1 
ATOM 3347 O O   . GLN C 2 202 ? 150.581 156.709 120.273 1.00 164.63 ? 202 GLN C O   1 
ATOM 3348 C CB  . GLN C 2 202 ? 152.858 158.838 119.219 1.00 161.20 ? 202 GLN C CB  1 
ATOM 3349 C CG  . GLN C 2 202 ? 152.847 157.780 118.131 1.00 159.78 ? 202 GLN C CG  1 
ATOM 3350 C CD  . GLN C 2 202 ? 153.589 158.219 116.885 1.00 159.96 ? 202 GLN C CD  1 
ATOM 3351 O OE1 . GLN C 2 202 ? 153.049 158.180 115.780 1.00 159.28 ? 202 GLN C OE1 1 
ATOM 3352 N NE2 . GLN C 2 202 ? 154.838 158.634 117.056 1.00 159.91 ? 202 GLN C NE2 1 
ATOM 3353 N N   . PRO C 2 203 ? 149.906 158.839 120.454 1.00 168.40 ? 203 PRO C N   1 
ATOM 3354 C CA  . PRO C 2 203 ? 148.495 158.466 120.289 1.00 166.82 ? 203 PRO C CA  1 
ATOM 3355 C C   . PRO C 2 203 ? 148.262 157.715 118.986 1.00 165.84 ? 203 PRO C C   1 
ATOM 3356 O O   . PRO C 2 203 ? 148.647 158.168 117.906 1.00 162.84 ? 203 PRO C O   1 
ATOM 3357 C CB  . PRO C 2 203 ? 147.772 159.816 120.302 1.00 163.46 ? 203 PRO C CB  1 
ATOM 3358 C CG  . PRO C 2 203 ? 148.663 160.705 121.096 1.00 163.34 ? 203 PRO C CG  1 
ATOM 3359 C CD  . PRO C 2 203 ? 150.065 160.269 120.773 1.00 165.39 ? 203 PRO C CD  1 
ATOM 3360 N N   . HIS C 2 204 ? 147.625 156.552 119.098 1.00 165.86 ? 204 HIS C N   1 
ATOM 3361 C CA  . HIS C 2 204 ? 147.397 155.670 117.965 1.00 159.93 ? 204 HIS C CA  1 
ATOM 3362 C C   . HIS C 2 204 ? 145.993 155.093 118.041 1.00 154.85 ? 204 HIS C C   1 
ATOM 3363 O O   . HIS C 2 204 ? 145.407 154.980 119.121 1.00 148.51 ? 204 HIS C O   1 
ATOM 3364 C CB  . HIS C 2 204 ? 148.418 154.525 117.926 1.00 155.70 ? 204 HIS C CB  1 
ATOM 3365 C CG  . HIS C 2 204 ? 149.511 154.721 116.922 1.00 157.10 ? 204 HIS C CG  1 
ATOM 3366 N ND1 . HIS C 2 204 ? 150.267 155.871 116.858 1.00 160.49 ? 204 HIS C ND1 1 
ATOM 3367 C CD2 . HIS C 2 204 ? 149.978 153.908 115.945 1.00 155.00 ? 204 HIS C CD2 1 
ATOM 3368 C CE1 . HIS C 2 204 ? 151.151 155.760 115.882 1.00 161.10 ? 204 HIS C CE1 1 
ATOM 3369 N NE2 . HIS C 2 204 ? 150.997 154.578 115.313 1.00 159.75 ? 204 HIS C NE2 1 
ATOM 3370 N N   . GLU C 2 205 ? 145.460 154.726 116.880 1.00 152.71 ? 205 GLU C N   1 
ATOM 3371 C CA  . GLU C 2 205 ? 144.197 154.008 116.802 1.00 148.55 ? 205 GLU C CA  1 
ATOM 3372 C C   . GLU C 2 205 ? 144.360 152.518 117.069 1.00 145.61 ? 205 GLU C C   1 
ATOM 3373 O O   . GLU C 2 205 ? 143.356 151.812 117.204 1.00 143.93 ? 205 GLU C O   1 
ATOM 3374 C CB  . GLU C 2 205 ? 143.550 154.223 115.429 1.00 148.16 ? 205 GLU C CB  1 
ATOM 3375 C CG  . GLU C 2 205 ? 143.234 155.677 115.114 1.00 150.01 ? 205 GLU C CG  1 
ATOM 3376 C CD  . GLU C 2 205 ? 142.599 155.854 113.748 1.00 149.33 ? 205 GLU C CD  1 
ATOM 3377 O OE1 . GLU C 2 205 ? 142.486 154.855 113.008 1.00 148.23 ? 205 GLU C OE1 1 
ATOM 3378 O OE2 . GLU C 2 205 ? 142.213 156.994 113.415 1.00 145.65 ? 205 GLU C OE2 1 
ATOM 3379 N N   . LYS C 2 206 ? 145.594 152.030 117.148 1.00 143.71 ? 206 LYS C N   1 
ATOM 3380 C CA  . LYS C 2 206 ? 145.886 150.637 117.450 1.00 132.95 ? 206 LYS C CA  1 
ATOM 3381 C C   . LYS C 2 206 ? 146.457 150.547 118.857 1.00 126.98 ? 206 LYS C C   1 
ATOM 3382 O O   . LYS C 2 206 ? 147.398 151.273 119.196 1.00 126.78 ? 206 LYS C O   1 
ATOM 3383 C CB  . LYS C 2 206 ? 146.880 150.052 116.445 1.00 129.27 ? 206 LYS C CB  1 
ATOM 3384 C CG  . LYS C 2 206 ? 146.508 150.273 114.990 1.00 131.02 ? 206 LYS C CG  1 
ATOM 3385 C CD  . LYS C 2 206 ? 145.199 149.591 114.644 1.00 134.00 ? 206 LYS C CD  1 
ATOM 3386 C CE  . LYS C 2 206 ? 144.889 149.725 113.164 1.00 137.23 ? 206 LYS C CE  1 
ATOM 3387 N NZ  . LYS C 2 206 ? 144.837 151.150 112.739 1.00 138.10 ? 206 LYS C NZ  1 
ATOM 3388 N N   . GLU C 2 207 ? 145.889 149.663 119.673 1.00 120.83 ? 207 GLU C N   1 
ATOM 3389 C CA  . GLU C 2 207 ? 146.371 149.456 121.029 1.00 112.74 ? 207 GLU C CA  1 
ATOM 3390 C C   . GLU C 2 207 ? 146.520 147.968 121.300 1.00 105.81 ? 207 GLU C C   1 
ATOM 3391 O O   . GLU C 2 207 ? 145.651 147.171 120.937 1.00 103.10 ? 207 GLU C O   1 
ATOM 3392 C CB  . GLU C 2 207 ? 145.433 150.086 122.065 1.00 110.49 ? 207 GLU C CB  1 
ATOM 3393 C CG  . GLU C 2 207 ? 145.417 151.604 122.041 1.00 119.44 ? 207 GLU C CG  1 
ATOM 3394 C CD  . GLU C 2 207 ? 144.898 152.200 123.335 1.00 125.09 ? 207 GLU C CD  1 
ATOM 3395 O OE1 . GLU C 2 207 ? 144.738 151.443 124.315 1.00 123.22 ? 207 GLU C OE1 1 
ATOM 3396 O OE2 . GLU C 2 207 ? 144.653 153.424 123.375 1.00 131.07 ? 207 GLU C OE2 1 
ATOM 3397 N N   . VAL C 2 208 ? 147.629 147.604 121.938 1.00 103.38 ? 208 VAL C N   1 
ATOM 3398 C CA  . VAL C 2 208 ? 147.915 146.227 122.317 1.00 96.98  ? 208 VAL C CA  1 
ATOM 3399 C C   . VAL C 2 208 ? 148.076 146.179 123.828 1.00 100.31 ? 208 VAL C C   1 
ATOM 3400 O O   . VAL C 2 208 ? 149.032 146.742 124.380 1.00 104.02 ? 208 VAL C O   1 
ATOM 3401 C CB  . VAL C 2 208 ? 149.169 145.687 121.614 1.00 98.65  ? 208 VAL C CB  1 
ATOM 3402 C CG1 . VAL C 2 208 ? 149.574 144.354 122.208 1.00 95.84  ? 208 VAL C CG1 1 
ATOM 3403 C CG2 . VAL C 2 208 ? 148.914 145.546 120.127 1.00 106.71 ? 208 VAL C CG2 1 
ATOM 3404 N N   . HIS C 2 209 ? 147.143 145.510 124.495 1.00 94.19  ? 209 HIS C N   1 
ATOM 3405 C CA  . HIS C 2 209 ? 147.188 145.320 125.934 1.00 86.90  ? 209 HIS C CA  1 
ATOM 3406 C C   . HIS C 2 209 ? 147.373 143.841 126.224 1.00 80.98  ? 209 HIS C C   1 
ATOM 3407 O O   . HIS C 2 209 ? 146.552 143.015 125.813 1.00 83.86  ? 209 HIS C O   1 
ATOM 3408 C CB  . HIS C 2 209 ? 145.915 145.839 126.600 1.00 82.30  ? 209 HIS C CB  1 
ATOM 3409 C CG  . HIS C 2 209 ? 145.742 147.318 126.492 1.00 82.16  ? 209 HIS C CG  1 
ATOM 3410 N ND1 . HIS C 2 209 ? 146.187 148.191 127.459 1.00 85.07  ? 209 HIS C ND1 1 
ATOM 3411 C CD2 . HIS C 2 209 ? 145.175 148.081 125.529 1.00 90.17  ? 209 HIS C CD2 1 
ATOM 3412 C CE1 . HIS C 2 209 ? 145.901 149.428 127.098 1.00 93.48  ? 209 HIS C CE1 1 
ATOM 3413 N NE2 . HIS C 2 209 ? 145.286 149.389 125.931 1.00 96.75  ? 209 HIS C NE2 1 
ATOM 3414 N N   . ILE C 2 210 ? 148.451 143.513 126.924 1.00 72.66  ? 210 ILE C N   1 
ATOM 3415 C CA  . ILE C 2 210 ? 148.760 142.148 127.318 1.00 68.01  ? 210 ILE C CA  1 
ATOM 3416 C C   . ILE C 2 210 ? 148.401 142.000 128.786 1.00 72.58  ? 210 ILE C C   1 
ATOM 3417 O O   . ILE C 2 210 ? 148.815 142.814 129.617 1.00 79.47  ? 210 ILE C O   1 
ATOM 3418 C CB  . ILE C 2 210 ? 150.238 141.810 127.070 1.00 68.14  ? 210 ILE C CB  1 
ATOM 3419 C CG1 . ILE C 2 210 ? 150.592 142.050 125.605 1.00 72.66  ? 210 ILE C CG1 1 
ATOM 3420 C CG2 . ILE C 2 210 ? 150.519 140.373 127.439 1.00 70.37  ? 210 ILE C CG2 1 
ATOM 3421 C CD1 . ILE C 2 210 ? 152.018 141.725 125.265 1.00 87.83  ? 210 ILE C CD1 1 
ATOM 3422 N N   . ILE C 2 211 ? 147.605 140.985 129.097 1.00 69.77  ? 211 ILE C N   1 
ATOM 3423 C CA  . ILE C 2 211 ? 147.170 140.710 130.458 1.00 61.99  ? 211 ILE C CA  1 
ATOM 3424 C C   . ILE C 2 211 ? 147.572 139.288 130.800 1.00 63.62  ? 211 ILE C C   1 
ATOM 3425 O O   . ILE C 2 211 ? 147.148 138.340 130.130 1.00 67.91  ? 211 ILE C O   1 
ATOM 3426 C CB  . ILE C 2 211 ? 145.654 140.903 130.617 1.00 58.03  ? 211 ILE C CB  1 
ATOM 3427 C CG1 . ILE C 2 211 ? 145.276 142.358 130.347 1.00 64.34  ? 211 ILE C CG1 1 
ATOM 3428 C CG2 . ILE C 2 211 ? 145.220 140.493 131.997 1.00 61.12  ? 211 ILE C CG2 1 
ATOM 3429 C CD1 . ILE C 2 211 ? 143.793 142.611 130.357 1.00 63.11  ? 211 ILE C CD1 1 
ATOM 3430 N N   . GLU C 2 212 ? 148.391 139.140 131.833 1.00 63.47  ? 212 GLU C N   1 
ATOM 3431 C CA  . GLU C 2 212 ? 148.852 137.843 132.295 1.00 63.01  ? 212 GLU C CA  1 
ATOM 3432 C C   . GLU C 2 212 ? 148.281 137.587 133.677 1.00 66.74  ? 212 GLU C C   1 
ATOM 3433 O O   . GLU C 2 212 ? 148.330 138.463 134.545 1.00 74.71  ? 212 GLU C O   1 
ATOM 3434 C CB  . GLU C 2 212 ? 150.377 137.773 132.333 1.00 71.18  ? 212 GLU C CB  1 
ATOM 3435 C CG  . GLU C 2 212 ? 150.907 136.414 132.740 1.00 83.55  ? 212 GLU C CG  1 
ATOM 3436 C CD  . GLU C 2 212 ? 152.415 136.349 132.726 1.00 107.21 ? 212 GLU C CD  1 
ATOM 3437 O OE1 . GLU C 2 212 ? 153.021 136.471 133.810 1.00 111.84 ? 212 GLU C OE1 1 
ATOM 3438 O OE2 . GLU C 2 212 ? 152.995 136.178 131.634 1.00 113.48 ? 212 GLU C OE2 1 
ATOM 3439 N N   . LEU C 2 213 ? 147.728 136.399 133.871 1.00 63.65  ? 213 LEU C N   1 
ATOM 3440 C CA  . LEU C 2 213 ? 147.127 136.007 135.133 1.00 60.72  ? 213 LEU C CA  1 
ATOM 3441 C C   . LEU C 2 213 ? 147.844 134.772 135.648 1.00 68.40  ? 213 LEU C C   1 
ATOM 3442 O O   . LEU C 2 213 ? 148.071 133.820 134.897 1.00 71.50  ? 213 LEU C O   1 
ATOM 3443 C CB  . LEU C 2 213 ? 145.638 135.726 134.962 1.00 54.41  ? 213 LEU C CB  1 
ATOM 3444 C CG  . LEU C 2 213 ? 144.883 135.260 136.197 1.00 58.29  ? 213 LEU C CG  1 
ATOM 3445 C CD1 . LEU C 2 213 ? 144.978 136.309 137.272 1.00 70.61  ? 213 LEU C CD1 1 
ATOM 3446 C CD2 . LEU C 2 213 ? 143.440 134.983 135.845 1.00 55.71  ? 213 LEU C CD2 1 
ATOM 3447 N N   . ILE C 2 214 ? 148.207 134.790 136.926 1.00 70.67  ? 214 ILE C N   1 
ATOM 3448 C CA  . ILE C 2 214 ? 148.956 133.683 137.505 1.00 68.40  ? 214 ILE C CA  1 
ATOM 3449 C C   . ILE C 2 214 ? 147.990 132.688 138.128 1.00 73.29  ? 214 ILE C C   1 
ATOM 3450 O O   . ILE C 2 214 ? 147.928 131.526 137.716 1.00 75.73  ? 214 ILE C O   1 
ATOM 3451 C CB  . ILE C 2 214 ? 149.979 134.185 138.537 1.00 65.34  ? 214 ILE C CB  1 
ATOM 3452 C CG1 . ILE C 2 214 ? 150.893 135.233 137.906 1.00 66.30  ? 214 ILE C CG1 1 
ATOM 3453 C CG2 . ILE C 2 214 ? 150.803 133.031 139.069 1.00 64.16  ? 214 ILE C CG2 1 
ATOM 3454 C CD1 . ILE C 2 214 ? 151.685 134.721 136.732 1.00 65.79  ? 214 ILE C CD1 1 
ATOM 3455 N N   . THR C 2 215 ? 147.224 133.137 139.118 1.00 77.43  ? 215 THR C N   1 
ATOM 3456 C CA  . THR C 2 215 ? 146.287 132.280 139.832 1.00 81.53  ? 215 THR C CA  1 
ATOM 3457 C C   . THR C 2 215 ? 144.884 132.856 139.717 1.00 79.03  ? 215 THR C C   1 
ATOM 3458 O O   . THR C 2 215 ? 144.621 133.943 140.259 1.00 74.40  ? 215 THR C O   1 
ATOM 3459 C CB  . THR C 2 215 ? 146.685 132.140 141.301 1.00 85.95  ? 215 THR C CB  1 
ATOM 3460 O OG1 . THR C 2 215 ? 147.943 131.460 141.394 1.00 87.12  ? 215 THR C OG1 1 
ATOM 3461 C CG2 . THR C 2 215 ? 145.635 131.355 142.063 1.00 86.13  ? 215 THR C CG2 1 
ATOM 3462 N N   . PRO C 2 216 ? 143.958 132.189 139.038 1.00 78.72  ? 216 PRO C N   1 
ATOM 3463 C CA  . PRO C 2 216 ? 142.617 132.759 138.876 1.00 74.62  ? 216 PRO C CA  1 
ATOM 3464 C C   . PRO C 2 216 ? 141.766 132.638 140.127 1.00 85.15  ? 216 PRO C C   1 
ATOM 3465 O O   . PRO C 2 216 ? 141.016 133.560 140.460 1.00 86.08  ? 216 PRO C O   1 
ATOM 3466 C CB  . PRO C 2 216 ? 142.031 131.935 137.727 1.00 68.08  ? 216 PRO C CB  1 
ATOM 3467 C CG  . PRO C 2 216 ? 142.705 130.620 137.845 1.00 72.02  ? 216 PRO C CG  1 
ATOM 3468 C CD  . PRO C 2 216 ? 144.098 130.898 138.344 1.00 74.75  ? 216 PRO C CD  1 
ATOM 3469 N N   . SER C 2 217 ? 141.876 131.516 140.833 1.00 86.53  ? 217 SER C N   1 
ATOM 3470 C CA  . SER C 2 217 ? 141.015 131.254 141.975 1.00 86.57  ? 217 SER C CA  1 
ATOM 3471 C C   . SER C 2 217 ? 141.792 130.502 143.043 1.00 92.76  ? 217 SER C C   1 
ATOM 3472 O O   . SER C 2 217 ? 142.791 129.838 142.755 1.00 89.97  ? 217 SER C O   1 
ATOM 3473 C CB  . SER C 2 217 ? 139.775 130.460 141.565 1.00 82.03  ? 217 SER C CB  1 
ATOM 3474 O OG  . SER C 2 217 ? 139.002 131.188 140.630 1.00 85.46  ? 217 SER C OG  1 
ATOM 3475 N N   . SER C 2 218 ? 141.308 130.606 144.281 1.00 96.42  ? 218 SER C N   1 
ATOM 3476 C CA  . SER C 2 218 ? 142.002 130.044 145.433 1.00 98.76  ? 218 SER C CA  1 
ATOM 3477 C C   . SER C 2 218 ? 141.787 128.545 145.600 1.00 96.24  ? 218 SER C C   1 
ATOM 3478 O O   . SER C 2 218 ? 142.468 127.934 146.430 1.00 93.85  ? 218 SER C O   1 
ATOM 3479 C CB  . SER C 2 218 ? 141.561 130.769 146.703 1.00 98.22  ? 218 SER C CB  1 
ATOM 3480 O OG  . SER C 2 218 ? 140.150 130.791 146.799 1.00 98.38  ? 218 SER C OG  1 
ATOM 3481 N N   . ASN C 2 219 ? 140.869 127.943 144.854 1.00 93.56  ? 219 ASN C N   1 
ATOM 3482 C CA  . ASN C 2 219 ? 140.645 126.512 144.986 1.00 89.31  ? 219 ASN C CA  1 
ATOM 3483 C C   . ASN C 2 219 ? 141.840 125.745 144.433 1.00 84.96  ? 219 ASN C C   1 
ATOM 3484 O O   . ASN C 2 219 ? 142.292 126.029 143.317 1.00 88.10  ? 219 ASN C O   1 
ATOM 3485 C CB  . ASN C 2 219 ? 139.370 126.088 144.260 1.00 87.80  ? 219 ASN C CB  1 
ATOM 3486 C CG  . ASN C 2 219 ? 139.397 126.423 142.788 1.00 89.26  ? 219 ASN C CG  1 
ATOM 3487 O OD1 . ASN C 2 219 ? 139.992 127.419 142.379 1.00 90.12  ? 219 ASN C OD1 1 
ATOM 3488 N ND2 . ASN C 2 219 ? 138.751 125.590 141.980 1.00 86.05  ? 219 ASN C ND2 1 
ATOM 3489 N N   . PRO C 2 220 ? 142.380 124.774 145.173 1.00 83.82  ? 220 PRO C N   1 
ATOM 3490 C CA  . PRO C 2 220 ? 143.493 123.975 144.647 1.00 89.71  ? 220 PRO C CA  1 
ATOM 3491 C C   . PRO C 2 220 ? 143.072 122.964 143.598 1.00 92.00  ? 220 PRO C C   1 
ATOM 3492 O O   . PRO C 2 220 ? 143.900 122.146 143.181 1.00 94.18  ? 220 PRO C O   1 
ATOM 3493 C CB  . PRO C 2 220 ? 144.033 123.277 145.900 1.00 92.75  ? 220 PRO C CB  1 
ATOM 3494 C CG  . PRO C 2 220 ? 142.837 123.146 146.777 1.00 94.70  ? 220 PRO C CG  1 
ATOM 3495 C CD  . PRO C 2 220 ? 141.998 124.369 146.534 1.00 91.29  ? 220 PRO C CD  1 
ATOM 3496 N N   . TYR C 2 221 ? 141.818 122.999 143.158 1.00 91.11  ? 221 TYR C N   1 
ATOM 3497 C CA  . TYR C 2 221 ? 141.277 122.079 142.161 1.00 87.90  ? 221 TYR C CA  1 
ATOM 3498 C C   . TYR C 2 221 ? 141.270 122.702 140.776 1.00 86.82  ? 221 TYR C C   1 
ATOM 3499 O O   . TYR C 2 221 ? 140.346 122.476 139.992 1.00 83.56  ? 221 TYR C O   1 
ATOM 3500 C CB  . TYR C 2 221 ? 139.869 121.646 142.554 1.00 81.50  ? 221 TYR C CB  1 
ATOM 3501 C CG  . TYR C 2 221 ? 139.733 120.178 142.858 1.00 78.97  ? 221 TYR C CG  1 
ATOM 3502 C CD1 . TYR C 2 221 ? 139.571 119.255 141.840 1.00 80.18  ? 221 TYR C CD1 1 
ATOM 3503 C CD2 . TYR C 2 221 ? 139.755 119.717 144.165 1.00 84.20  ? 221 TYR C CD2 1 
ATOM 3504 C CE1 . TYR C 2 221 ? 139.441 117.910 142.112 1.00 87.96  ? 221 TYR C CE1 1 
ATOM 3505 C CE2 . TYR C 2 221 ? 139.625 118.374 144.449 1.00 89.65  ? 221 TYR C CE2 1 
ATOM 3506 C CZ  . TYR C 2 221 ? 139.469 117.474 143.418 1.00 94.88  ? 221 TYR C CZ  1 
ATOM 3507 O OH  . TYR C 2 221 ? 139.340 116.133 143.691 1.00 105.84 ? 221 TYR C OH  1 
ATOM 3508 N N   . SER C 2 222 ? 142.299 123.481 140.440 1.00 87.72  ? 222 SER C N   1 
ATOM 3509 C CA  . SER C 2 222 ? 142.262 124.345 139.262 1.00 81.39  ? 222 SER C CA  1 
ATOM 3510 C C   . SER C 2 222 ? 142.378 123.525 137.975 1.00 77.75  ? 222 SER C C   1 
ATOM 3511 O O   . SER C 2 222 ? 143.270 123.707 137.149 1.00 76.96  ? 222 SER C O   1 
ATOM 3512 C CB  . SER C 2 222 ? 143.363 125.393 139.347 1.00 81.68  ? 222 SER C CB  1 
ATOM 3513 O OG  . SER C 2 222 ? 143.220 126.180 140.514 1.00 88.06  ? 222 SER C OG  1 
ATOM 3514 N N   . ALA C 2 223 ? 141.430 122.605 137.825 1.00 76.29  ? 223 ALA C N   1 
ATOM 3515 C CA  . ALA C 2 223 ? 141.159 121.942 136.563 1.00 72.93  ? 223 ALA C CA  1 
ATOM 3516 C C   . ALA C 2 223 ? 139.849 122.412 135.953 1.00 71.81  ? 223 ALA C C   1 
ATOM 3517 O O   . ALA C 2 223 ? 139.481 121.952 134.868 1.00 75.66  ? 223 ALA C O   1 
ATOM 3518 C CB  . ALA C 2 223 ? 141.131 120.422 136.753 1.00 70.78  ? 223 ALA C CB  1 
ATOM 3519 N N   . PHE C 2 224 ? 139.142 123.317 136.622 1.00 66.50  ? 224 PHE C N   1 
ATOM 3520 C CA  . PHE C 2 224 ? 137.844 123.798 136.178 1.00 60.43  ? 224 PHE C CA  1 
ATOM 3521 C C   . PHE C 2 224 ? 137.960 125.257 135.773 1.00 56.49  ? 224 PHE C C   1 
ATOM 3522 O O   . PHE C 2 224 ? 138.664 126.031 136.426 1.00 57.44  ? 224 PHE C O   1 
ATOM 3523 C CB  . PHE C 2 224 ? 136.802 123.636 137.281 1.00 61.13  ? 224 PHE C CB  1 
ATOM 3524 C CG  . PHE C 2 224 ? 136.748 122.257 137.846 1.00 66.27  ? 224 PHE C CG  1 
ATOM 3525 C CD1 . PHE C 2 224 ? 136.170 121.228 137.133 1.00 66.02  ? 224 PHE C CD1 1 
ATOM 3526 C CD2 . PHE C 2 224 ? 137.286 121.983 139.084 1.00 73.80  ? 224 PHE C CD2 1 
ATOM 3527 C CE1 . PHE C 2 224 ? 136.129 119.954 137.645 1.00 68.50  ? 224 PHE C CE1 1 
ATOM 3528 C CE2 . PHE C 2 224 ? 137.243 120.707 139.603 1.00 77.94  ? 224 PHE C CE2 1 
ATOM 3529 C CZ  . PHE C 2 224 ? 136.664 119.693 138.882 1.00 73.71  ? 224 PHE C CZ  1 
ATOM 3530 N N   . GLN C 2 225 ? 137.276 125.624 134.696 1.00 58.13  ? 225 GLN C N   1 
ATOM 3531 C CA  . GLN C 2 225 ? 137.361 126.989 134.207 1.00 56.07  ? 225 GLN C CA  1 
ATOM 3532 C C   . GLN C 2 225 ? 136.725 127.951 135.199 1.00 55.02  ? 225 GLN C C   1 
ATOM 3533 O O   . GLN C 2 225 ? 135.856 127.584 135.991 1.00 61.74  ? 225 GLN C O   1 
ATOM 3534 C CB  . GLN C 2 225 ? 136.674 127.120 132.850 1.00 55.57  ? 225 GLN C CB  1 
ATOM 3535 C CG  . GLN C 2 225 ? 137.347 126.381 131.717 1.00 62.73  ? 225 GLN C CG  1 
ATOM 3536 C CD  . GLN C 2 225 ? 136.571 126.499 130.427 1.00 69.32  ? 225 GLN C CD  1 
ATOM 3537 O OE1 . GLN C 2 225 ? 135.362 126.714 130.437 1.00 63.92  ? 225 GLN C OE1 1 
ATOM 3538 N NE2 . GLN C 2 225 ? 137.259 126.347 129.306 1.00 74.61  ? 225 GLN C NE2 1 
ATOM 3539 N N   . VAL C 2 226 ? 137.188 129.196 135.158 1.00 48.08  ? 226 VAL C N   1 
ATOM 3540 C CA  . VAL C 2 226 ? 136.617 130.283 135.933 1.00 42.41  ? 226 VAL C CA  1 
ATOM 3541 C C   . VAL C 2 226 ? 136.403 131.444 134.977 1.00 49.30  ? 226 VAL C C   1 
ATOM 3542 O O   . VAL C 2 226 ? 137.131 131.610 133.999 1.00 61.39  ? 226 VAL C O   1 
ATOM 3543 C CB  . VAL C 2 226 ? 137.527 130.693 137.110 1.00 45.71  ? 226 VAL C CB  1 
ATOM 3544 C CG1 . VAL C 2 226 ? 136.878 131.774 137.958 1.00 53.75  ? 226 VAL C CG1 1 
ATOM 3545 C CG2 . VAL C 2 226 ? 137.864 129.483 137.960 1.00 52.85  ? 226 VAL C CG2 1 
ATOM 3546 N N   . ASP C 2 227 ? 135.388 132.249 135.257 1.00 45.48  ? 227 ASP C N   1 
ATOM 3547 C CA  . ASP C 2 227 ? 135.082 133.412 134.441 1.00 42.95  ? 227 ASP C CA  1 
ATOM 3548 C C   . ASP C 2 227 ? 135.940 134.580 134.895 1.00 44.77  ? 227 ASP C C   1 
ATOM 3549 O O   . ASP C 2 227 ? 135.834 135.018 136.042 1.00 50.73  ? 227 ASP C O   1 
ATOM 3550 C CB  . ASP C 2 227 ? 133.604 133.778 134.547 1.00 51.00  ? 227 ASP C CB  1 
ATOM 3551 C CG  . ASP C 2 227 ? 132.890 133.700 133.219 1.00 60.20  ? 227 ASP C CG  1 
ATOM 3552 O OD1 . ASP C 2 227 ? 133.488 133.180 132.259 1.00 58.28  ? 227 ASP C OD1 1 
ATOM 3553 O OD2 . ASP C 2 227 ? 131.734 134.162 133.132 1.00 71.03  ? 227 ASP C OD2 1 
ATOM 3554 N N   . ILE C 2 228 ? 136.779 135.084 134.001 1.00 41.85  ? 228 ILE C N   1 
ATOM 3555 C CA  . ILE C 2 228 ? 137.621 136.239 134.283 1.00 40.85  ? 228 ILE C CA  1 
ATOM 3556 C C   . ILE C 2 228 ? 137.043 137.402 133.491 1.00 43.28  ? 228 ILE C C   1 
ATOM 3557 O O   . ILE C 2 228 ? 137.442 137.652 132.350 1.00 50.01  ? 228 ILE C O   1 
ATOM 3558 C CB  . ILE C 2 228 ? 139.083 135.987 133.912 1.00 38.84  ? 228 ILE C CB  1 
ATOM 3559 C CG1 . ILE C 2 228 ? 139.544 134.640 134.451 1.00 42.52  ? 228 ILE C CG1 1 
ATOM 3560 C CG2 . ILE C 2 228 ? 139.956 137.084 134.457 1.00 45.83  ? 228 ILE C CG2 1 
ATOM 3561 C CD1 . ILE C 2 228 ? 139.562 134.561 135.937 1.00 49.01  ? 228 ILE C CD1 1 
ATOM 3562 N N   . ILE C 2 229 ? 136.130 138.138 134.101 1.00 44.66  ? 229 ILE C N   1 
ATOM 3563 C CA  . ILE C 2 229 ? 135.365 139.162 133.405 1.00 46.56  ? 229 ILE C CA  1 
ATOM 3564 C C   . ILE C 2 229 ? 136.245 140.380 133.183 1.00 48.36  ? 229 ILE C C   1 
ATOM 3565 O O   . ILE C 2 229 ? 136.841 140.908 134.127 1.00 60.25  ? 229 ILE C O   1 
ATOM 3566 C CB  . ILE C 2 229 ? 134.104 139.528 134.199 1.00 55.12  ? 229 ILE C CB  1 
ATOM 3567 C CG1 . ILE C 2 229 ? 133.198 138.303 134.315 1.00 55.57  ? 229 ILE C CG1 1 
ATOM 3568 C CG2 . ILE C 2 229 ? 133.383 140.681 133.544 1.00 64.83  ? 229 ILE C CG2 1 
ATOM 3569 C CD1 . ILE C 2 229 ? 131.920 138.551 135.065 1.00 66.49  ? 229 ILE C CD1 1 
ATOM 3570 N N   . VAL C 2 230 ? 136.328 140.831 131.937 1.00 46.49  ? 230 VAL C N   1 
ATOM 3571 C CA  . VAL C 2 230 ? 137.126 141.993 131.566 1.00 53.86  ? 230 VAL C CA  1 
ATOM 3572 C C   . VAL C 2 230 ? 136.174 143.122 131.204 1.00 69.47  ? 230 VAL C C   1 
ATOM 3573 O O   . VAL C 2 230 ? 135.403 143.008 130.244 1.00 77.91  ? 230 VAL C O   1 
ATOM 3574 C CB  . VAL C 2 230 ? 138.075 141.681 130.401 1.00 47.19  ? 230 VAL C CB  1 
ATOM 3575 C CG1 . VAL C 2 230 ? 138.795 142.932 129.958 1.00 50.10  ? 230 VAL C CG1 1 
ATOM 3576 C CG2 . VAL C 2 230 ? 139.069 140.615 130.801 1.00 47.75  ? 230 VAL C CG2 1 
ATOM 3577 N N   . ASP C 2 231 ? 136.232 144.214 131.958 1.00 69.82  ? 231 ASP C N   1 
ATOM 3578 C CA  . ASP C 2 231 ? 135.431 145.400 131.689 1.00 72.35  ? 231 ASP C CA  1 
ATOM 3579 C C   . ASP C 2 231 ? 136.246 146.374 130.853 1.00 78.76  ? 231 ASP C C   1 
ATOM 3580 O O   . ASP C 2 231 ? 137.373 146.721 131.222 1.00 82.85  ? 231 ASP C O   1 
ATOM 3581 C CB  . ASP C 2 231 ? 134.986 146.079 132.986 1.00 80.80  ? 231 ASP C CB  1 
ATOM 3582 C CG  . ASP C 2 231 ? 133.972 145.263 133.757 1.00 88.47  ? 231 ASP C CG  1 
ATOM 3583 O OD1 . ASP C 2 231 ? 134.382 144.418 134.579 1.00 85.55  ? 231 ASP C OD1 1 
ATOM 3584 O OD2 . ASP C 2 231 ? 132.759 145.470 133.546 1.00 92.84  ? 231 ASP C OD2 1 
ATOM 3585 N N   . ILE C 2 232 ? 135.679 146.811 129.733 1.00 78.30  ? 232 ILE C N   1 
ATOM 3586 C CA  . ILE C 2 232 ? 136.302 147.802 128.865 1.00 83.64  ? 232 ILE C CA  1 
ATOM 3587 C C   . ILE C 2 232 ? 135.360 148.990 128.763 1.00 96.51  ? 232 ILE C C   1 
ATOM 3588 O O   . ILE C 2 232 ? 134.375 148.947 128.016 1.00 100.48 ? 232 ILE C O   1 
ATOM 3589 C CB  . ILE C 2 232 ? 136.615 147.233 127.475 1.00 81.59  ? 232 ILE C CB  1 
ATOM 3590 C CG1 . ILE C 2 232 ? 137.400 145.932 127.598 1.00 80.16  ? 232 ILE C CG1 1 
ATOM 3591 C CG2 . ILE C 2 232 ? 137.405 148.237 126.664 1.00 85.61  ? 232 ILE C CG2 1 
ATOM 3592 C CD1 . ILE C 2 232 ? 137.775 145.328 126.271 1.00 79.84  ? 232 ILE C CD1 1 
ATOM 3593 N N   . ARG C 2 233 ? 135.662 150.052 129.509 1.00 105.11 ? 233 ARG C N   1 
ATOM 3594 C CA  . ARG C 2 233 ? 134.848 151.251 129.536 1.00 111.54 ? 233 ARG C CA  1 
ATOM 3595 C C   . ARG C 2 233 ? 135.794 152.438 129.453 1.00 119.92 ? 233 ARG C C   1 
ATOM 3596 O O   . ARG C 2 233 ? 136.951 152.324 129.880 1.00 119.64 ? 233 ARG C O   1 
ATOM 3597 C CB  . ARG C 2 233 ? 133.998 151.332 130.808 1.00 108.21 ? 233 ARG C CB  1 
ATOM 3598 C CG  . ARG C 2 233 ? 133.067 150.149 130.986 1.00 105.80 ? 233 ARG C CG  1 
ATOM 3599 C CD  . ARG C 2 233 ? 132.743 149.902 132.445 1.00 104.14 ? 233 ARG C CD  1 
ATOM 3600 N NE  . ARG C 2 233 ? 131.420 150.393 132.804 1.00 109.43 ? 233 ARG C NE  1 
ATOM 3601 C CZ  . ARG C 2 233 ? 130.833 150.167 133.971 1.00 115.09 ? 233 ARG C CZ  1 
ATOM 3602 N NH1 . ARG C 2 233 ? 131.427 149.457 134.916 1.00 115.40 ? 233 ARG C NH1 1 
ATOM 3603 N NH2 . ARG C 2 233 ? 129.620 150.663 134.194 1.00 116.50 ? 233 ARG C NH2 1 
ATOM 3604 N N   . PRO C 2 234 ? 135.352 153.568 128.911 1.00 124.56 ? 234 PRO C N   1 
ATOM 3605 C CA  . PRO C 2 234 ? 136.256 154.709 128.745 1.00 130.92 ? 234 PRO C CA  1 
ATOM 3606 C C   . PRO C 2 234 ? 136.502 155.420 130.065 1.00 134.18 ? 234 PRO C C   1 
ATOM 3607 O O   . PRO C 2 234 ? 135.904 155.116 131.099 1.00 133.26 ? 234 PRO C O   1 
ATOM 3608 C CB  . PRO C 2 234 ? 135.516 155.618 127.758 1.00 135.80 ? 234 PRO C CB  1 
ATOM 3609 C CG  . PRO C 2 234 ? 134.365 154.808 127.241 1.00 129.96 ? 234 PRO C CG  1 
ATOM 3610 C CD  . PRO C 2 234 ? 134.038 153.825 128.305 1.00 122.41 ? 234 PRO C CD  1 
ATOM 3611 N N   . ALA C 2 235 ? 137.423 156.386 130.013 1.00 139.89 ? 235 ALA C N   1 
ATOM 3612 C CA  . ALA C 2 235 ? 137.601 157.299 131.136 1.00 147.00 ? 235 ALA C CA  1 
ATOM 3613 C C   . ALA C 2 235 ? 136.344 158.125 131.365 1.00 152.55 ? 235 ALA C C   1 
ATOM 3614 O O   . ALA C 2 235 ? 135.940 158.353 132.512 1.00 150.66 ? 235 ALA C O   1 
ATOM 3615 C CB  . ALA C 2 235 ? 138.805 158.207 130.892 1.00 140.86 ? 235 ALA C CB  1 
ATOM 3616 N N   . GLN C 2 236 ? 135.718 158.585 130.285 1.00 154.07 ? 236 GLN C N   1 
ATOM 3617 C CA  . GLN C 2 236 ? 134.440 159.282 130.343 1.00 154.49 ? 236 GLN C CA  1 
ATOM 3618 C C   . GLN C 2 236 ? 133.552 158.735 129.237 1.00 153.76 ? 236 GLN C C   1 
ATOM 3619 O O   . GLN C 2 236 ? 134.030 158.471 128.129 1.00 150.25 ? 236 GLN C O   1 
ATOM 3620 C CB  . GLN C 2 236 ? 134.615 160.797 130.191 1.00 157.40 ? 236 GLN C CB  1 
ATOM 3621 C CG  . GLN C 2 236 ? 135.399 161.465 131.314 1.00 157.20 ? 236 GLN C CG  1 
ATOM 3622 C CD  . GLN C 2 236 ? 136.900 161.358 131.129 1.00 158.93 ? 236 GLN C CD  1 
ATOM 3623 O OE1 . GLN C 2 236 ? 137.382 161.034 130.044 1.00 159.54 ? 236 GLN C OE1 1 
ATOM 3624 N NE2 . GLN C 2 236 ? 137.648 161.629 132.192 1.00 156.66 ? 236 GLN C NE2 1 
ATOM 3625 N N   . GLU C 2 237 ? 132.263 158.562 129.539 1.00 157.17 ? 237 GLU C N   1 
ATOM 3626 C CA  . GLU C 2 237 ? 131.324 158.094 128.525 1.00 155.87 ? 237 GLU C CA  1 
ATOM 3627 C C   . GLU C 2 237 ? 131.238 159.073 127.363 1.00 163.32 ? 237 GLU C C   1 
ATOM 3628 O O   . GLU C 2 237 ? 131.222 158.667 126.195 1.00 162.05 ? 237 GLU C O   1 
ATOM 3629 C CB  . GLU C 2 237 ? 129.945 157.884 129.149 1.00 152.24 ? 237 GLU C CB  1 
ATOM 3630 C CG  . GLU C 2 237 ? 129.947 156.971 130.361 1.00 149.98 ? 237 GLU C CG  1 
ATOM 3631 C CD  . GLU C 2 237 ? 128.577 156.847 130.995 1.00 143.35 ? 237 GLU C CD  1 
ATOM 3632 O OE1 . GLU C 2 237 ? 127.630 157.492 130.498 1.00 139.23 ? 237 GLU C OE1 1 
ATOM 3633 O OE2 . GLU C 2 237 ? 128.446 156.104 131.991 1.00 146.43 ? 237 GLU C OE2 1 
ATOM 3634 N N   . ASP C 2 238 ? 131.186 160.372 127.667 1.00 166.66 ? 238 ASP C N   1 
ATOM 3635 C CA  . ASP C 2 238 ? 131.122 161.411 126.650 1.00 166.27 ? 238 ASP C CA  1 
ATOM 3636 C C   . ASP C 2 238 ? 132.390 162.245 126.697 1.00 166.68 ? 238 ASP C C   1 
ATOM 3637 O O   . ASP C 2 238 ? 132.745 162.751 127.775 1.00 164.19 ? 238 ASP C O   1 
ATOM 3638 C CB  . ASP C 2 238 ? 129.901 162.298 126.866 1.00 162.35 ? 238 ASP C CB  1 
ATOM 3639 C CG  . ASP C 2 238 ? 128.607 161.510 126.902 1.00 161.35 ? 238 ASP C CG  1 
ATOM 3640 O OD1 . ASP C 2 238 ? 128.399 160.754 127.874 1.00 161.74 ? 238 ASP C OD1 1 
ATOM 3641 O OD2 . ASP C 2 238 ? 127.797 161.646 125.961 1.00 158.89 ? 238 ASP C OD2 1 
ATOM 3642 N N   . PRO C 2 239 ? 133.104 162.422 125.579 1.00 169.30 ? 239 PRO C N   1 
ATOM 3643 C CA  . PRO C 2 239 ? 132.821 161.884 124.242 1.00 167.83 ? 239 PRO C CA  1 
ATOM 3644 C C   . PRO C 2 239 ? 133.205 160.414 124.123 1.00 165.78 ? 239 PRO C C   1 
ATOM 3645 O O   . PRO C 2 239 ? 134.099 159.941 124.819 1.00 161.82 ? 239 PRO C O   1 
ATOM 3646 C CB  . PRO C 2 239 ? 133.672 162.778 123.333 1.00 165.54 ? 239 PRO C CB  1 
ATOM 3647 C CG  . PRO C 2 239 ? 134.861 163.118 124.182 1.00 165.44 ? 239 PRO C CG  1 
ATOM 3648 C CD  . PRO C 2 239 ? 134.313 163.266 125.582 1.00 167.76 ? 239 PRO C CD  1 
ATOM 3649 N N   . GLU C 2 240 ? 132.540 159.670 123.245 1.00 166.03 ? 240 GLU C N   1 
ATOM 3650 C CA  . GLU C 2 240 ? 132.853 158.265 123.054 1.00 161.28 ? 240 GLU C CA  1 
ATOM 3651 C C   . GLU C 2 240 ? 134.158 158.107 122.280 1.00 157.43 ? 240 GLU C C   1 
ATOM 3652 O O   . GLU C 2 240 ? 134.638 159.031 121.619 1.00 156.14 ? 240 GLU C O   1 
ATOM 3653 C CB  . GLU C 2 240 ? 131.717 157.550 122.321 1.00 159.53 ? 240 GLU C CB  1 
ATOM 3654 C CG  . GLU C 2 240 ? 130.488 157.275 123.176 1.00 159.54 ? 240 GLU C CG  1 
ATOM 3655 C CD  . GLU C 2 240 ? 129.686 158.524 123.483 1.00 163.76 ? 240 GLU C CD  1 
ATOM 3656 O OE1 . GLU C 2 240 ? 129.861 159.536 122.773 1.00 162.88 ? 240 GLU C OE1 1 
ATOM 3657 O OE2 . GLU C 2 240 ? 128.881 158.493 124.438 1.00 163.01 ? 240 GLU C OE2 1 
ATOM 3658 N N   . VAL C 2 241 ? 134.732 156.911 122.369 1.00 155.12 ? 241 VAL C N   1 
ATOM 3659 C CA  . VAL C 2 241 ? 136.013 156.603 121.746 1.00 152.40 ? 241 VAL C CA  1 
ATOM 3660 C C   . VAL C 2 241 ? 135.844 155.405 120.822 1.00 145.15 ? 241 VAL C C   1 
ATOM 3661 O O   . VAL C 2 241 ? 135.204 154.410 121.184 1.00 140.38 ? 241 VAL C O   1 
ATOM 3662 C CB  . VAL C 2 241 ? 137.108 156.338 122.801 1.00 150.32 ? 241 VAL C CB  1 
ATOM 3663 C CG1 . VAL C 2 241 ? 136.673 155.251 123.775 1.00 144.86 ? 241 VAL C CG1 1 
ATOM 3664 C CG2 . VAL C 2 241 ? 138.421 155.969 122.128 1.00 147.12 ? 241 VAL C CG2 1 
ATOM 3665 N N   . VAL C 2 242 ? 136.405 155.515 119.621 1.00 144.78 ? 242 VAL C N   1 
ATOM 3666 C CA  . VAL C 2 242 ? 136.451 154.427 118.653 1.00 143.25 ? 242 VAL C CA  1 
ATOM 3667 C C   . VAL C 2 242 ? 137.912 154.065 118.425 1.00 144.41 ? 242 VAL C C   1 
ATOM 3668 O O   . VAL C 2 242 ? 138.734 154.935 118.114 1.00 146.69 ? 242 VAL C O   1 
ATOM 3669 C CB  . VAL C 2 242 ? 135.754 154.809 117.335 1.00 137.90 ? 242 VAL C CB  1 
ATOM 3670 C CG1 . VAL C 2 242 ? 136.470 155.974 116.665 1.00 137.48 ? 242 VAL C CG1 1 
ATOM 3671 C CG2 . VAL C 2 242 ? 135.687 153.609 116.402 1.00 135.63 ? 242 VAL C CG2 1 
ATOM 3672 N N   . LYS C 2 243 ? 138.234 152.785 118.589 1.00 140.65 ? 243 LYS C N   1 
ATOM 3673 C CA  . LYS C 2 243 ? 139.619 152.342 118.548 1.00 136.01 ? 243 LYS C CA  1 
ATOM 3674 C C   . LYS C 2 243 ? 139.701 150.905 118.055 1.00 132.39 ? 243 LYS C C   1 
ATOM 3675 O O   . LYS C 2 243 ? 138.690 150.244 117.797 1.00 130.94 ? 243 LYS C O   1 
ATOM 3676 C CB  . LYS C 2 243 ? 140.283 152.465 119.924 1.00 135.80 ? 243 LYS C CB  1 
ATOM 3677 C CG  . LYS C 2 243 ? 140.925 153.814 120.192 1.00 140.71 ? 243 LYS C CG  1 
ATOM 3678 C CD  . LYS C 2 243 ? 141.519 153.874 121.588 1.00 140.59 ? 243 LYS C CD  1 
ATOM 3679 C CE  . LYS C 2 243 ? 142.394 155.102 121.761 1.00 144.08 ? 243 LYS C CE  1 
ATOM 3680 N NZ  . LYS C 2 243 ? 141.671 156.355 121.414 1.00 147.96 ? 243 LYS C NZ  1 
ATOM 3681 N N   . ASN C 2 244 ? 140.937 150.434 117.919 1.00 133.81 ? 244 ASN C N   1 
ATOM 3682 C CA  . ASN C 2 244 ? 141.239 149.046 117.595 1.00 131.67 ? 244 ASN C CA  1 
ATOM 3683 C C   . ASN C 2 244 ? 142.027 148.461 118.761 1.00 128.54 ? 244 ASN C C   1 
ATOM 3684 O O   . ASN C 2 244 ? 143.190 148.818 118.975 1.00 127.96 ? 244 ASN C O   1 
ATOM 3685 C CB  . ASN C 2 244 ? 142.019 148.943 116.288 1.00 131.60 ? 244 ASN C CB  1 
ATOM 3686 C CG  . ASN C 2 244 ? 141.316 149.630 115.137 1.00 133.29 ? 244 ASN C CG  1 
ATOM 3687 O OD1 . ASN C 2 244 ? 141.917 150.419 114.409 1.00 136.02 ? 244 ASN C OD1 1 
ATOM 3688 N ND2 . ASN C 2 244 ? 140.032 149.338 114.971 1.00 131.96 ? 244 ASN C ND2 1 
ATOM 3689 N N   . LEU C 2 245 ? 141.391 147.567 119.506 1.00 122.11 ? 245 LEU C N   1 
ATOM 3690 C CA  . LEU C 2 245 ? 141.979 146.956 120.689 1.00 110.68 ? 245 LEU C CA  1 
ATOM 3691 C C   . LEU C 2 245 ? 142.468 145.557 120.354 1.00 103.98 ? 245 LEU C C   1 
ATOM 3692 O O   . LEU C 2 245 ? 141.797 144.817 119.630 1.00 104.68 ? 245 LEU C O   1 
ATOM 3693 C CB  . LEU C 2 245 ? 140.974 146.898 121.839 1.00 110.09 ? 245 LEU C CB  1 
ATOM 3694 C CG  . LEU C 2 245 ? 140.744 148.197 122.607 1.00 116.21 ? 245 LEU C CG  1 
ATOM 3695 C CD1 . LEU C 2 245 ? 139.787 147.972 123.764 1.00 108.83 ? 245 LEU C CD1 1 
ATOM 3696 C CD2 . LEU C 2 245 ? 142.066 148.753 123.104 1.00 112.20 ? 245 LEU C CD2 1 
ATOM 3697 N N   . VAL C 2 246 ? 143.640 145.209 120.870 1.00 100.46 ? 246 VAL C N   1 
ATOM 3698 C CA  . VAL C 2 246 ? 144.206 143.874 120.738 1.00 97.10  ? 246 VAL C CA  1 
ATOM 3699 C C   . VAL C 2 246 ? 144.544 143.413 122.148 1.00 90.74  ? 246 VAL C C   1 
ATOM 3700 O O   . VAL C 2 246 ? 145.593 143.773 122.695 1.00 87.50  ? 246 VAL C O   1 
ATOM 3701 C CB  . VAL C 2 246 ? 145.441 143.854 119.833 1.00 100.40 ? 246 VAL C CB  1 
ATOM 3702 C CG1 . VAL C 2 246 ? 146.039 142.463 119.785 1.00 96.79  ? 246 VAL C CG1 1 
ATOM 3703 C CG2 . VAL C 2 246 ? 145.080 144.325 118.436 1.00 104.34 ? 246 VAL C CG2 1 
ATOM 3704 N N   . LEU C 2 247 ? 143.654 142.631 122.750 1.00 86.13  ? 247 LEU C N   1 
ATOM 3705 C CA  . LEU C 2 247 ? 143.865 142.118 124.097 1.00 76.21  ? 247 LEU C CA  1 
ATOM 3706 C C   . LEU C 2 247 ? 144.571 140.773 124.018 1.00 78.08  ? 247 LEU C C   1 
ATOM 3707 O O   . LEU C 2 247 ? 143.990 139.793 123.542 1.00 82.87  ? 247 LEU C O   1 
ATOM 3708 C CB  . LEU C 2 247 ? 142.540 141.966 124.839 1.00 71.43  ? 247 LEU C CB  1 
ATOM 3709 C CG  . LEU C 2 247 ? 141.830 143.217 125.344 1.00 73.54  ? 247 LEU C CG  1 
ATOM 3710 C CD1 . LEU C 2 247 ? 140.595 142.812 126.119 1.00 73.75  ? 247 LEU C CD1 1 
ATOM 3711 C CD2 . LEU C 2 247 ? 142.756 144.041 126.208 1.00 76.06  ? 247 LEU C CD2 1 
ATOM 3712 N N   . ILE C 2 248 ? 145.808 140.722 124.493 1.00 72.17  ? 248 ILE C N   1 
ATOM 3713 C CA  . ILE C 2 248 ? 146.555 139.477 124.599 1.00 67.05  ? 248 ILE C CA  1 
ATOM 3714 C C   . ILE C 2 248 ? 146.403 138.986 126.030 1.00 65.78  ? 248 ILE C C   1 
ATOM 3715 O O   . ILE C 2 248 ? 147.009 139.536 126.954 1.00 70.81  ? 248 ILE C O   1 
ATOM 3716 C CB  . ILE C 2 248 ? 148.030 139.660 124.225 1.00 67.60  ? 248 ILE C CB  1 
ATOM 3717 C CG1 . ILE C 2 248 ? 148.155 140.150 122.786 1.00 74.02  ? 248 ILE C CG1 1 
ATOM 3718 C CG2 . ILE C 2 248 ? 148.783 138.357 124.401 1.00 69.56  ? 248 ILE C CG2 1 
ATOM 3719 C CD1 . ILE C 2 248 ? 149.569 140.456 122.377 1.00 85.82  ? 248 ILE C CD1 1 
ATOM 3720 N N   . LEU C 2 249 ? 145.598 137.950 126.219 1.00 59.94  ? 249 LEU C N   1 
ATOM 3721 C CA  . LEU C 2 249 ? 145.281 137.427 127.537 1.00 54.65  ? 249 LEU C CA  1 
ATOM 3722 C C   . LEU C 2 249 ? 145.995 136.100 127.721 1.00 58.83  ? 249 LEU C C   1 
ATOM 3723 O O   . LEU C 2 249 ? 145.986 135.260 126.819 1.00 68.64  ? 249 LEU C O   1 
ATOM 3724 C CB  . LEU C 2 249 ? 143.772 137.253 127.695 1.00 51.01  ? 249 LEU C CB  1 
ATOM 3725 C CG  . LEU C 2 249 ? 142.941 138.455 127.251 1.00 56.76  ? 249 LEU C CG  1 
ATOM 3726 C CD1 . LEU C 2 249 ? 141.467 138.153 127.369 1.00 55.86  ? 249 LEU C CD1 1 
ATOM 3727 C CD2 . LEU C 2 249 ? 143.298 139.674 128.073 1.00 61.98  ? 249 LEU C CD2 1 
ATOM 3728 N N   . LYS C 2 250 ? 146.620 135.913 128.879 1.00 56.05  ? 250 LYS C N   1 
ATOM 3729 C CA  . LYS C 2 250 ? 147.370 134.697 129.159 1.00 56.33  ? 250 LYS C CA  1 
ATOM 3730 C C   . LYS C 2 250 ? 147.080 134.237 130.577 1.00 61.61  ? 250 LYS C C   1 
ATOM 3731 O O   . LYS C 2 250 ? 147.122 135.041 131.513 1.00 68.79  ? 250 LYS C O   1 
ATOM 3732 C CB  . LYS C 2 250 ? 148.870 134.923 128.967 1.00 66.03  ? 250 LYS C CB  1 
ATOM 3733 C CG  . LYS C 2 250 ? 149.727 133.746 129.385 1.00 76.95  ? 250 LYS C CG  1 
ATOM 3734 C CD  . LYS C 2 250 ? 149.325 132.484 128.646 1.00 80.22  ? 250 LYS C CD  1 
ATOM 3735 C CE  . LYS C 2 250 ? 150.107 131.286 129.145 1.00 82.12  ? 250 LYS C CE  1 
ATOM 3736 N NZ  . LYS C 2 250 ? 149.690 130.032 128.466 1.00 81.82  ? 250 LYS C NZ  1 
ATOM 3737 N N   . CYS C 2 251 ? 146.794 132.948 130.733 1.00 62.97  ? 251 CYS C N   1 
ATOM 3738 C CA  . CYS C 2 251 ? 146.647 132.332 132.045 1.00 67.28  ? 251 CYS C CA  1 
ATOM 3739 C C   . CYS C 2 251 ? 146.924 130.846 131.901 1.00 73.01  ? 251 CYS C C   1 
ATOM 3740 O O   . CYS C 2 251 ? 146.214 130.153 131.168 1.00 75.02  ? 251 CYS C O   1 
ATOM 3741 C CB  . CYS C 2 251 ? 145.251 132.566 132.621 1.00 65.04  ? 251 CYS C CB  1 
ATOM 3742 S SG  . CYS C 2 251 ? 144.998 131.839 134.251 1.00 83.41  ? 251 CYS C SG  1 
ATOM 3743 N N   . LYS C 2 252 ? 147.958 130.362 132.593 1.00 73.87  ? 252 LYS C N   1 
ATOM 3744 C CA  . LYS C 2 252 ? 148.319 128.951 132.496 1.00 73.49  ? 252 LYS C CA  1 
ATOM 3745 C C   . LYS C 2 252 ? 147.192 128.058 132.994 1.00 76.17  ? 252 LYS C C   1 
ATOM 3746 O O   . LYS C 2 252 ? 146.850 127.060 132.350 1.00 75.94  ? 252 LYS C O   1 
ATOM 3747 C CB  . LYS C 2 252 ? 149.604 128.688 133.278 1.00 77.24  ? 252 LYS C CB  1 
ATOM 3748 C CG  . LYS C 2 252 ? 150.792 129.505 132.799 1.00 83.80  ? 252 LYS C CG  1 
ATOM 3749 C CD  . LYS C 2 252 ? 152.012 129.286 133.679 1.00 87.07  ? 252 LYS C CD  1 
ATOM 3750 C CE  . LYS C 2 252 ? 152.446 127.831 133.677 1.00 87.18  ? 252 LYS C CE  1 
ATOM 3751 N NZ  . LYS C 2 252 ? 153.614 127.603 134.571 1.00 83.17  ? 252 LYS C NZ  1 
ATOM 3752 N N   . LYS C 2 253 ? 146.600 128.399 134.133 1.00 75.15  ? 253 LYS C N   1 
ATOM 3753 C CA  . LYS C 2 253 ? 145.417 127.695 134.596 1.00 70.11  ? 253 LYS C CA  1 
ATOM 3754 C C   . LYS C 2 253 ? 144.251 127.980 133.662 1.00 68.76  ? 253 LYS C C   1 
ATOM 3755 O O   . LYS C 2 253 ? 144.172 129.041 133.040 1.00 71.13  ? 253 LYS C O   1 
ATOM 3756 C CB  . LYS C 2 253 ? 145.058 128.104 136.023 1.00 69.55  ? 253 LYS C CB  1 
ATOM 3757 C CG  . LYS C 2 253 ? 145.752 127.294 137.106 1.00 77.10  ? 253 LYS C CG  1 
ATOM 3758 C CD  . LYS C 2 253 ? 147.229 127.634 137.211 1.00 86.38  ? 253 LYS C CD  1 
ATOM 3759 C CE  . LYS C 2 253 ? 147.890 126.871 138.346 1.00 90.66  ? 253 LYS C CE  1 
ATOM 3760 N NZ  . LYS C 2 253 ? 149.326 127.232 138.491 1.00 90.88  ? 253 LYS C NZ  1 
ATOM 3761 N N   . SER C 2 254 ? 143.345 127.014 133.559 1.00 67.31  ? 254 SER C N   1 
ATOM 3762 C CA  . SER C 2 254 ? 142.228 127.141 132.636 1.00 65.80  ? 254 SER C CA  1 
ATOM 3763 C C   . SER C 2 254 ? 141.230 128.175 133.136 1.00 59.18  ? 254 SER C C   1 
ATOM 3764 O O   . SER C 2 254 ? 140.755 128.099 134.270 1.00 64.33  ? 254 SER C O   1 
ATOM 3765 C CB  . SER C 2 254 ? 141.545 125.789 132.461 1.00 68.73  ? 254 SER C CB  1 
ATOM 3766 O OG  . SER C 2 254 ? 141.263 125.207 133.721 1.00 73.59  ? 254 SER C OG  1 
ATOM 3767 N N   . VAL C 2 255 ? 140.915 129.146 132.279 1.00 49.02  ? 255 VAL C N   1 
ATOM 3768 C CA  . VAL C 2 255 ? 139.921 130.175 132.558 1.00 46.14  ? 255 VAL C CA  1 
ATOM 3769 C C   . VAL C 2 255 ? 139.096 130.385 131.296 1.00 50.34  ? 255 VAL C C   1 
ATOM 3770 O O   . VAL C 2 255 ? 139.299 129.722 130.280 1.00 61.58  ? 255 VAL C O   1 
ATOM 3771 C CB  . VAL C 2 255 ? 140.552 131.508 133.006 1.00 47.11  ? 255 VAL C CB  1 
ATOM 3772 C CG1 . VAL C 2 255 ? 141.328 131.326 134.283 1.00 55.77  ? 255 VAL C CG1 1 
ATOM 3773 C CG2 . VAL C 2 255 ? 141.440 132.042 131.928 1.00 53.94  ? 255 VAL C CG2 1 
ATOM 3774 N N   . ASN C 2 256 ? 138.146 131.311 131.368 1.00 46.58  ? 256 ASN C N   1 
ATOM 3775 C CA  . ASN C 2 256 ? 137.174 131.554 130.306 1.00 49.09  ? 256 ASN C CA  1 
ATOM 3776 C C   . ASN C 2 256 ? 136.992 133.046 130.068 1.00 45.83  ? 256 ASN C C   1 
ATOM 3777 O O   . ASN C 2 256 ? 135.882 133.568 130.164 1.00 52.83  ? 256 ASN C O   1 
ATOM 3778 C CB  . ASN C 2 256 ? 135.835 130.899 130.617 1.00 55.14  ? 256 ASN C CB  1 
ATOM 3779 C CG  . ASN C 2 256 ? 134.905 130.883 129.421 1.00 60.38  ? 256 ASN C CG  1 
ATOM 3780 O OD1 . ASN C 2 256 ? 135.348 130.811 128.276 1.00 61.86  ? 256 ASN C OD1 1 
ATOM 3781 N ND2 . ASN C 2 256 ? 133.608 130.959 129.680 1.00 55.65  ? 256 ASN C ND2 1 
ATOM 3782 N N   . TRP C 2 257 ? 138.090 133.757 129.803 1.00 40.92  ? 257 TRP C N   1 
ATOM 3783 C CA  . TRP C 2 257 ? 138.087 135.211 129.665 1.00 44.06  ? 257 TRP C CA  1 
ATOM 3784 C C   . TRP C 2 257 ? 136.827 135.712 128.978 1.00 52.32  ? 257 TRP C C   1 
ATOM 3785 O O   . TRP C 2 257 ? 136.538 135.342 127.838 1.00 60.06  ? 257 TRP C O   1 
ATOM 3786 C CB  . TRP C 2 257 ? 139.305 135.656 128.855 1.00 44.39  ? 257 TRP C CB  1 
ATOM 3787 C CG  . TRP C 2 257 ? 140.619 135.386 129.479 1.00 45.81  ? 257 TRP C CG  1 
ATOM 3788 C CD1 . TRP C 2 257 ? 141.375 134.272 129.333 1.00 43.30  ? 257 TRP C CD1 1 
ATOM 3789 C CD2 . TRP C 2 257 ? 141.357 136.264 130.331 1.00 48.06  ? 257 TRP C CD2 1 
ATOM 3790 N NE1 . TRP C 2 257 ? 142.534 134.390 130.051 1.00 47.60  ? 257 TRP C NE1 1 
ATOM 3791 C CE2 . TRP C 2 257 ? 142.545 135.606 130.676 1.00 49.82  ? 257 TRP C CE2 1 
ATOM 3792 C CE3 . TRP C 2 257 ? 141.121 137.542 130.842 1.00 46.07  ? 257 TRP C CE3 1 
ATOM 3793 C CZ2 . TRP C 2 257 ? 143.498 136.179 131.507 1.00 53.52  ? 257 TRP C CZ2 1 
ATOM 3794 C CZ3 . TRP C 2 257 ? 142.067 138.108 131.666 1.00 45.68  ? 257 TRP C CZ3 1 
ATOM 3795 C CH2 . TRP C 2 257 ? 143.240 137.429 131.991 1.00 49.59  ? 257 TRP C CH2 1 
ATOM 3796 N N   . VAL C 2 258 ? 136.077 136.560 129.676 1.00 51.29  ? 258 VAL C N   1 
ATOM 3797 C CA  . VAL C 2 258 ? 134.827 137.124 129.182 1.00 49.25  ? 258 VAL C CA  1 
ATOM 3798 C C   . VAL C 2 258 ? 135.035 138.614 128.981 1.00 54.89  ? 258 VAL C C   1 
ATOM 3799 O O   . VAL C 2 258 ? 135.387 139.327 129.926 1.00 59.98  ? 258 VAL C O   1 
ATOM 3800 C CB  . VAL C 2 258 ? 133.665 136.862 130.152 1.00 45.97  ? 258 VAL C CB  1 
ATOM 3801 C CG1 . VAL C 2 258 ? 132.511 137.782 129.845 1.00 62.66  ? 258 VAL C CG1 1 
ATOM 3802 C CG2 . VAL C 2 258 ? 133.221 135.427 130.058 1.00 48.79  ? 258 VAL C CG2 1 
ATOM 3803 N N   . ILE C 2 259 ? 134.811 139.084 127.762 1.00 57.75  ? 259 ILE C N   1 
ATOM 3804 C CA  . ILE C 2 259 ? 135.102 140.461 127.389 1.00 63.95  ? 259 ILE C CA  1 
ATOM 3805 C C   . ILE C 2 259 ? 133.793 141.232 127.356 1.00 69.53  ? 259 ILE C C   1 
ATOM 3806 O O   . ILE C 2 259 ? 132.877 140.885 126.602 1.00 75.09  ? 259 ILE C O   1 
ATOM 3807 C CB  . ILE C 2 259 ? 135.819 140.541 126.036 1.00 72.12  ? 259 ILE C CB  1 
ATOM 3808 C CG1 . ILE C 2 259 ? 136.947 139.514 125.973 1.00 71.44  ? 259 ILE C CG1 1 
ATOM 3809 C CG2 . ILE C 2 259 ? 136.364 141.936 125.815 1.00 74.59  ? 259 ILE C CG2 1 
ATOM 3810 C CD1 . ILE C 2 259 ? 138.017 139.721 127.009 1.00 66.17  ? 259 ILE C CD1 1 
ATOM 3811 N N   . LYS C 2 260 ? 133.705 142.273 128.173 1.00 71.24  ? 260 LYS C N   1 
ATOM 3812 C CA  . LYS C 2 260 ? 132.561 143.168 128.200 1.00 76.99  ? 260 LYS C CA  1 
ATOM 3813 C C   . LYS C 2 260 ? 133.041 144.587 127.952 1.00 83.87  ? 260 LYS C C   1 
ATOM 3814 O O   . LYS C 2 260 ? 133.952 145.070 128.632 1.00 82.38  ? 260 LYS C O   1 
ATOM 3815 C CB  . LYS C 2 260 ? 131.827 143.091 129.538 1.00 76.95  ? 260 LYS C CB  1 
ATOM 3816 C CG  . LYS C 2 260 ? 131.364 141.701 129.909 1.00 72.97  ? 260 LYS C CG  1 
ATOM 3817 C CD  . LYS C 2 260 ? 130.626 141.703 131.232 1.00 74.46  ? 260 LYS C CD  1 
ATOM 3818 C CE  . LYS C 2 260 ? 130.058 140.329 131.538 1.00 71.66  ? 260 LYS C CE  1 
ATOM 3819 N NZ  . LYS C 2 260 ? 129.242 140.323 132.781 1.00 69.85  ? 260 LYS C NZ  1 
ATOM 3820 N N   . SER C 2 261 ? 132.429 145.254 126.977 1.00 94.62  ? 261 SER C N   1 
ATOM 3821 C CA  . SER C 2 261 ? 132.814 146.607 126.597 1.00 100.59 ? 261 SER C CA  1 
ATOM 3822 C C   . SER C 2 261 ? 131.577 147.489 126.589 1.00 107.18 ? 261 SER C C   1 
ATOM 3823 O O   . SER C 2 261 ? 130.543 147.103 126.036 1.00 110.50 ? 261 SER C O   1 
ATOM 3824 C CB  . SER C 2 261 ? 133.491 146.622 125.226 1.00 102.82 ? 261 SER C CB  1 
ATOM 3825 O OG  . SER C 2 261 ? 132.540 146.444 124.195 1.00 112.92 ? 261 SER C OG  1 
ATOM 3826 N N   . PHE C 2 262 ? 131.683 148.666 127.198 1.00 107.47 ? 262 PHE C N   1 
ATOM 3827 C CA  . PHE C 2 262 ? 130.587 149.623 127.275 1.00 112.75 ? 262 PHE C CA  1 
ATOM 3828 C C   . PHE C 2 262 ? 131.044 150.969 126.731 1.00 116.78 ? 262 PHE C C   1 
ATOM 3829 O O   . PHE C 2 262 ? 132.157 151.416 127.028 1.00 117.46 ? 262 PHE C O   1 
ATOM 3830 C CB  . PHE C 2 262 ? 130.100 149.789 128.717 1.00 111.37 ? 262 PHE C CB  1 
ATOM 3831 C CG  . PHE C 2 262 ? 129.729 148.500 129.390 1.00 106.58 ? 262 PHE C CG  1 
ATOM 3832 C CD1 . PHE C 2 262 ? 129.041 147.514 128.708 1.00 105.39 ? 262 PHE C CD1 1 
ATOM 3833 C CD2 . PHE C 2 262 ? 130.070 148.278 130.711 1.00 104.27 ? 262 PHE C CD2 1 
ATOM 3834 C CE1 . PHE C 2 262 ? 128.703 146.333 129.331 1.00 103.57 ? 262 PHE C CE1 1 
ATOM 3835 C CE2 . PHE C 2 262 ? 129.734 147.098 131.338 1.00 102.33 ? 262 PHE C CE2 1 
ATOM 3836 C CZ  . PHE C 2 262 ? 129.049 146.126 130.648 1.00 101.08 ? 262 PHE C CZ  1 
ATOM 3837 N N   . ASP C 2 263 ? 130.184 151.606 125.938 1.00 118.82 ? 263 ASP C N   1 
ATOM 3838 C CA  . ASP C 2 263 ? 130.389 152.979 125.472 1.00 125.18 ? 263 ASP C CA  1 
ATOM 3839 C C   . ASP C 2 263 ? 131.712 153.134 124.723 1.00 126.68 ? 263 ASP C C   1 
ATOM 3840 O O   . ASP C 2 263 ? 132.396 154.156 124.817 1.00 128.83 ? 263 ASP C O   1 
ATOM 3841 C CB  . ASP C 2 263 ? 130.305 153.964 126.639 1.00 129.94 ? 263 ASP C CB  1 
ATOM 3842 C CG  . ASP C 2 263 ? 128.994 153.865 127.390 1.00 130.50 ? 263 ASP C CG  1 
ATOM 3843 O OD1 . ASP C 2 263 ? 128.780 152.847 128.081 1.00 125.82 ? 263 ASP C OD1 1 
ATOM 3844 O OD2 . ASP C 2 263 ? 128.176 154.803 127.288 1.00 132.86 ? 263 ASP C OD2 1 
ATOM 3845 N N   . VAL C 2 264 ? 132.069 152.103 123.965 1.00 125.58 ? 264 VAL C N   1 
ATOM 3846 C CA  . VAL C 2 264 ? 133.278 152.120 123.147 1.00 126.38 ? 264 VAL C CA  1 
ATOM 3847 C C   . VAL C 2 264 ? 132.942 151.527 121.790 1.00 124.62 ? 264 VAL C C   1 
ATOM 3848 O O   . VAL C 2 264 ? 132.174 150.566 121.700 1.00 121.16 ? 264 VAL C O   1 
ATOM 3849 C CB  . VAL C 2 264 ? 134.432 151.345 123.807 1.00 125.82 ? 264 VAL C CB  1 
ATOM 3850 C CG1 . VAL C 2 264 ? 135.038 152.156 124.933 1.00 125.61 ? 264 VAL C CG1 1 
ATOM 3851 C CG2 . VAL C 2 264 ? 133.932 150.020 124.330 1.00 118.74 ? 264 VAL C CG2 1 
ATOM 3852 N N   . LYS C 2 265 ? 133.505 152.100 120.734 1.00 128.97 ? 265 LYS C N   1 
ATOM 3853 C CA  . LYS C 2 265 ? 133.293 151.618 119.380 1.00 130.57 ? 265 LYS C CA  1 
ATOM 3854 C C   . LYS C 2 265 ? 134.622 151.218 118.754 1.00 133.11 ? 265 LYS C C   1 
ATOM 3855 O O   . LYS C 2 265 ? 135.701 151.560 119.244 1.00 135.00 ? 265 LYS C O   1 
ATOM 3856 C CB  . LYS C 2 265 ? 132.599 152.683 118.524 1.00 130.56 ? 265 LYS C CB  1 
ATOM 3857 C CG  . LYS C 2 265 ? 131.236 153.113 119.041 1.00 127.77 ? 265 LYS C CG  1 
ATOM 3858 C CD  . LYS C 2 265 ? 130.580 154.109 118.097 1.00 123.84 ? 265 LYS C CD  1 
ATOM 3859 C CE  . LYS C 2 265 ? 129.205 154.526 118.594 1.00 121.63 ? 265 LYS C CE  1 
ATOM 3860 N NZ  . LYS C 2 265 ? 129.274 155.232 119.902 1.00 127.34 ? 265 LYS C NZ  1 
ATOM 3861 N N   . GLY C 2 266 ? 134.535 150.481 117.659 1.00 131.70 ? 266 GLY C N   1 
ATOM 3862 C CA  . GLY C 2 266 ? 135.703 150.120 116.885 1.00 130.87 ? 266 GLY C CA  1 
ATOM 3863 C C   . GLY C 2 266 ? 135.831 148.622 116.720 1.00 128.36 ? 266 GLY C C   1 
ATOM 3864 O O   . GLY C 2 266 ? 134.857 147.866 116.797 1.00 127.48 ? 266 GLY C O   1 
ATOM 3865 N N   . ASN C 2 267 ? 137.067 148.192 116.494 1.00 128.96 ? 267 ASN C N   1 
ATOM 3866 C CA  . ASN C 2 267 ? 137.378 146.791 116.238 1.00 127.21 ? 267 ASN C CA  1 
ATOM 3867 C C   . ASN C 2 267 ? 138.166 146.232 117.414 1.00 125.67 ? 267 ASN C C   1 
ATOM 3868 O O   . ASN C 2 267 ? 139.168 146.821 117.829 1.00 126.12 ? 267 ASN C O   1 
ATOM 3869 C CB  . ASN C 2 267 ? 138.166 146.642 114.937 1.00 126.88 ? 267 ASN C CB  1 
ATOM 3870 C CG  . ASN C 2 267 ? 138.396 145.194 114.557 1.00 127.71 ? 267 ASN C CG  1 
ATOM 3871 O OD1 . ASN C 2 267 ? 139.393 144.587 114.949 1.00 124.61 ? 267 ASN C OD1 1 
ATOM 3872 N ND2 . ASN C 2 267 ? 137.473 144.631 113.786 1.00 128.94 ? 267 ASN C ND2 1 
ATOM 3873 N N   . LEU C 2 268 ? 137.714 145.102 117.951 1.00 121.89 ? 268 LEU C N   1 
ATOM 3874 C CA  . LEU C 2 268 ? 138.345 144.476 119.108 1.00 116.09 ? 268 LEU C CA  1 
ATOM 3875 C C   . LEU C 2 268 ? 138.722 143.044 118.754 1.00 110.06 ? 268 LEU C C   1 
ATOM 3876 O O   . LEU C 2 268 ? 137.886 142.280 118.257 1.00 110.49 ? 268 LEU C O   1 
ATOM 3877 C CB  . LEU C 2 268 ? 137.417 144.510 120.319 1.00 114.30 ? 268 LEU C CB  1 
ATOM 3878 C CG  . LEU C 2 268 ? 138.042 144.055 121.637 1.00 107.56 ? 268 LEU C CG  1 
ATOM 3879 C CD1 . LEU C 2 268 ? 137.446 144.820 122.797 1.00 104.69 ? 268 LEU C CD1 1 
ATOM 3880 C CD2 . LEU C 2 268 ? 137.851 142.564 121.827 1.00 105.41 ? 268 LEU C CD2 1 
ATOM 3881 N N   . LYS C 2 269 ? 139.973 142.682 119.015 1.00 103.25 ? 269 LYS C N   1 
ATOM 3882 C CA  . LYS C 2 269 ? 140.476 141.332 118.814 1.00 101.72 ? 269 LYS C CA  1 
ATOM 3883 C C   . LYS C 2 269 ? 141.042 140.825 120.131 1.00 96.94  ? 269 LYS C C   1 
ATOM 3884 O O   . LYS C 2 269 ? 141.691 141.580 120.863 1.00 93.87  ? 269 LYS C O   1 
ATOM 3885 C CB  . LYS C 2 269 ? 141.549 141.301 117.724 1.00 104.60 ? 269 LYS C CB  1 
ATOM 3886 C CG  . LYS C 2 269 ? 142.075 139.911 117.409 1.00 100.31 ? 269 LYS C CG  1 
ATOM 3887 C CD  . LYS C 2 269 ? 143.158 139.954 116.346 1.00 100.10 ? 269 LYS C CD  1 
ATOM 3888 C CE  . LYS C 2 269 ? 142.638 140.546 115.049 1.00 107.18 ? 269 LYS C CE  1 
ATOM 3889 N NZ  . LYS C 2 269 ? 143.699 140.606 114.007 1.00 108.19 ? 269 LYS C NZ  1 
ATOM 3890 N N   . VAL C 2 270 ? 140.780 139.557 120.436 1.00 91.96  ? 270 VAL C N   1 
ATOM 3891 C CA  . VAL C 2 270 ? 141.208 138.930 121.679 1.00 78.87  ? 270 VAL C CA  1 
ATOM 3892 C C   . VAL C 2 270 ? 141.993 137.675 121.333 1.00 78.49  ? 270 VAL C C   1 
ATOM 3893 O O   . VAL C 2 270 ? 141.513 136.831 120.569 1.00 84.91  ? 270 VAL C O   1 
ATOM 3894 C CB  . VAL C 2 270 ? 140.007 138.587 122.576 1.00 76.99  ? 270 VAL C CB  1 
ATOM 3895 C CG1 . VAL C 2 270 ? 140.475 138.243 123.963 1.00 82.04  ? 270 VAL C CG1 1 
ATOM 3896 C CG2 . VAL C 2 270 ? 139.024 139.740 122.615 1.00 78.73  ? 270 VAL C CG2 1 
ATOM 3897 N N   . ILE C 2 271 ? 143.192 137.549 121.894 1.00 71.66  ? 271 ILE C N   1 
ATOM 3898 C CA  . ILE C 2 271 ? 144.066 136.409 121.644 1.00 72.75  ? 271 ILE C CA  1 
ATOM 3899 C C   . ILE C 2 271 ? 144.444 135.799 122.983 1.00 67.18  ? 271 ILE C C   1 
ATOM 3900 O O   . ILE C 2 271 ? 145.109 136.450 123.795 1.00 70.24  ? 271 ILE C O   1 
ATOM 3901 C CB  . ILE C 2 271 ? 145.326 136.819 120.861 1.00 80.90  ? 271 ILE C CB  1 
ATOM 3902 C CG1 . ILE C 2 271 ? 144.955 137.535 119.562 1.00 87.85  ? 271 ILE C CG1 1 
ATOM 3903 C CG2 . ILE C 2 271 ? 146.173 135.605 120.550 1.00 88.97  ? 271 ILE C CG2 1 
ATOM 3904 C CD1 . ILE C 2 271 ? 144.919 139.037 119.674 1.00 88.62  ? 271 ILE C CD1 1 
ATOM 3905 N N   . ALA C 2 272 ? 144.044 134.552 123.208 1.00 64.16  ? 272 ALA C N   1 
ATOM 3906 C CA  . ALA C 2 272 ? 144.285 133.911 124.492 1.00 64.85  ? 272 ALA C CA  1 
ATOM 3907 C C   . ALA C 2 272 ? 144.295 132.406 124.294 1.00 63.57  ? 272 ALA C C   1 
ATOM 3908 O O   . ALA C 2 272 ? 143.446 131.866 123.578 1.00 68.69  ? 272 ALA C O   1 
ATOM 3909 C CB  . ALA C 2 272 ? 143.219 134.308 125.522 1.00 67.57  ? 272 ALA C CB  1 
ATOM 3910 N N   . PRO C 2 273 ? 145.232 131.699 124.931 1.00 62.38  ? 273 PRO C N   1 
ATOM 3911 C CA  . PRO C 2 273 ? 145.253 130.235 124.817 1.00 70.60  ? 273 PRO C CA  1 
ATOM 3912 C C   . PRO C 2 273 ? 144.057 129.550 125.446 1.00 70.22  ? 273 PRO C C   1 
ATOM 3913 O O   . PRO C 2 273 ? 143.692 128.453 125.003 1.00 73.33  ? 273 PRO C O   1 
ATOM 3914 C CB  . PRO C 2 273 ? 146.546 129.848 125.544 1.00 73.02  ? 273 PRO C CB  1 
ATOM 3915 C CG  . PRO C 2 273 ? 146.772 130.954 126.500 1.00 68.82  ? 273 PRO C CG  1 
ATOM 3916 C CD  . PRO C 2 273 ? 146.298 132.197 125.812 1.00 65.73  ? 273 PRO C CD  1 
ATOM 3917 N N   . ASN C 2 274 ? 143.439 130.150 126.456 1.00 67.42  ? 274 ASN C N   1 
ATOM 3918 C CA  . ASN C 2 274 ? 142.263 129.585 127.092 1.00 62.45  ? 274 ASN C CA  1 
ATOM 3919 C C   . ASN C 2 274 ? 141.032 129.922 126.263 1.00 54.73  ? 274 ASN C C   1 
ATOM 3920 O O   . ASN C 2 274 ? 141.120 130.492 125.174 1.00 58.63  ? 274 ASN C O   1 
ATOM 3921 C CB  . ASN C 2 274 ? 142.120 130.108 128.521 1.00 62.94  ? 274 ASN C CB  1 
ATOM 3922 C CG  . ASN C 2 274 ? 143.167 129.545 129.454 1.00 63.56  ? 274 ASN C CG  1 
ATOM 3923 O OD1 . ASN C 2 274 ? 143.083 128.393 129.875 1.00 61.78  ? 274 ASN C OD1 1 
ATOM 3924 N ND2 . ASN C 2 274 ? 144.166 130.353 129.778 1.00 66.91  ? 274 ASN C ND2 1 
ATOM 3925 N N   . SER C 2 275 ? 139.865 129.567 126.787 1.00 45.90  ? 275 SER C N   1 
ATOM 3926 C CA  . SER C 2 275 ? 138.627 129.944 126.125 1.00 50.01  ? 275 SER C CA  1 
ATOM 3927 C C   . SER C 2 275 ? 138.450 131.454 126.179 1.00 50.42  ? 275 SER C C   1 
ATOM 3928 O O   . SER C 2 275 ? 139.043 132.134 127.018 1.00 53.31  ? 275 SER C O   1 
ATOM 3929 C CB  . SER C 2 275 ? 137.438 129.248 126.780 1.00 53.57  ? 275 SER C CB  1 
ATOM 3930 O OG  . SER C 2 275 ? 136.224 129.659 126.178 1.00 58.45  ? 275 SER C OG  1 
ATOM 3931 N N   . ILE C 2 276 ? 137.656 131.983 125.254 1.00 48.23  ? 276 ILE C N   1 
ATOM 3932 C CA  . ILE C 2 276 ? 137.304 133.395 125.231 1.00 49.78  ? 276 ILE C CA  1 
ATOM 3933 C C   . ILE C 2 276 ? 135.809 133.492 124.981 1.00 54.39  ? 276 ILE C C   1 
ATOM 3934 O O   . ILE C 2 276 ? 135.258 132.719 124.192 1.00 61.06  ? 276 ILE C O   1 
ATOM 3935 C CB  . ILE C 2 276 ? 138.085 134.173 124.155 1.00 56.56  ? 276 ILE C CB  1 
ATOM 3936 C CG1 . ILE C 2 276 ? 139.586 133.980 124.335 1.00 56.78  ? 276 ILE C CG1 1 
ATOM 3937 C CG2 . ILE C 2 276 ? 137.763 135.650 124.221 1.00 57.01  ? 276 ILE C CG2 1 
ATOM 3938 C CD1 . ILE C 2 276 ? 140.408 134.695 123.300 1.00 64.99  ? 276 ILE C CD1 1 
ATOM 3939 N N   . GLY C 2 277 ? 135.151 134.426 125.665 1.00 55.94  ? 277 GLY C N   1 
ATOM 3940 C CA  . GLY C 2 277 ? 133.731 134.640 125.501 1.00 66.37  ? 277 GLY C CA  1 
ATOM 3941 C C   . GLY C 2 277 ? 133.405 136.120 125.420 1.00 73.76  ? 277 GLY C C   1 
ATOM 3942 O O   . GLY C 2 277 ? 134.280 136.979 125.543 1.00 74.52  ? 277 GLY C O   1 
ATOM 3943 N N   . PHE C 2 278 ? 132.123 136.392 125.203 1.00 79.16  ? 278 PHE C N   1 
ATOM 3944 C CA  . PHE C 2 278 ? 131.600 137.746 125.178 1.00 83.34  ? 278 PHE C CA  1 
ATOM 3945 C C   . PHE C 2 278 ? 130.293 137.778 125.952 1.00 88.44  ? 278 PHE C C   1 
ATOM 3946 O O   . PHE C 2 278 ? 129.662 136.746 126.188 1.00 90.82  ? 278 PHE C O   1 
ATOM 3947 C CB  . PHE C 2 278 ? 131.371 138.249 123.747 1.00 93.28  ? 278 PHE C CB  1 
ATOM 3948 C CG  . PHE C 2 278 ? 132.481 137.907 122.796 1.00 95.72  ? 278 PHE C CG  1 
ATOM 3949 C CD1 . PHE C 2 278 ? 133.708 138.535 122.887 1.00 90.51  ? 278 PHE C CD1 1 
ATOM 3950 C CD2 . PHE C 2 278 ? 132.291 136.964 121.804 1.00 97.09  ? 278 PHE C CD2 1 
ATOM 3951 C CE1 . PHE C 2 278 ? 134.724 138.222 122.014 1.00 93.94  ? 278 PHE C CE1 1 
ATOM 3952 C CE2 . PHE C 2 278 ? 133.306 136.649 120.928 1.00 95.14  ? 278 PHE C CE2 1 
ATOM 3953 C CZ  . PHE C 2 278 ? 134.523 137.278 121.034 1.00 95.89  ? 278 PHE C CZ  1 
ATOM 3954 N N   . GLY C 2 279 ? 129.893 138.977 126.349 1.00 96.51  ? 279 GLY C N   1 
ATOM 3955 C CA  . GLY C 2 279 ? 128.657 139.159 127.077 1.00 106.52 ? 279 GLY C CA  1 
ATOM 3956 C C   . GLY C 2 279 ? 127.454 139.192 126.157 1.00 115.15 ? 279 GLY C C   1 
ATOM 3957 O O   . GLY C 2 279 ? 127.536 138.904 124.961 1.00 114.59 ? 279 GLY C O   1 
ATOM 3958 N N   . LYS C 2 280 ? 126.315 139.553 126.737 1.00 116.84 ? 280 LYS C N   1 
ATOM 3959 C CA  . LYS C 2 280 ? 125.086 139.707 125.979 1.00 122.68 ? 280 LYS C CA  1 
ATOM 3960 C C   . LYS C 2 280 ? 125.210 140.864 124.990 1.00 123.97 ? 280 LYS C C   1 
ATOM 3961 O O   . LYS C 2 280 ? 126.225 141.563 124.927 1.00 120.48 ? 280 LYS C O   1 
ATOM 3962 C CB  . LYS C 2 280 ? 123.899 139.936 126.915 1.00 123.56 ? 280 LYS C CB  1 
ATOM 3963 C CG  . LYS C 2 280 ? 123.415 138.694 127.653 1.00 121.95 ? 280 LYS C CG  1 
ATOM 3964 C CD  . LYS C 2 280 ? 124.285 138.363 128.855 1.00 119.83 ? 280 LYS C CD  1 
ATOM 3965 C CE  . LYS C 2 280 ? 123.739 137.166 129.612 1.00 119.53 ? 280 LYS C CE  1 
ATOM 3966 N NZ  . LYS C 2 280 ? 123.626 135.970 128.734 1.00 123.26 ? 280 LYS C NZ  1 
ATOM 3967 N N   . GLU C 2 281 ? 124.149 141.062 124.203 1.00 128.01 ? 281 GLU C N   1 
ATOM 3968 C CA  . GLU C 2 281 ? 124.165 142.120 123.199 1.00 126.14 ? 281 GLU C CA  1 
ATOM 3969 C C   . GLU C 2 281 ? 124.307 143.495 123.836 1.00 125.33 ? 281 GLU C C   1 
ATOM 3970 O O   . GLU C 2 281 ? 124.879 144.405 123.226 1.00 123.55 ? 281 GLU C O   1 
ATOM 3971 C CB  . GLU C 2 281 ? 122.899 142.051 122.345 1.00 128.76 ? 281 GLU C CB  1 
ATOM 3972 C CG  . GLU C 2 281 ? 122.926 142.946 121.118 1.00 134.61 ? 281 GLU C CG  1 
ATOM 3973 C CD  . GLU C 2 281 ? 121.714 142.753 120.230 1.00 141.03 ? 281 GLU C CD  1 
ATOM 3974 O OE1 . GLU C 2 281 ? 120.863 141.902 120.563 1.00 145.14 ? 281 GLU C OE1 1 
ATOM 3975 O OE2 . GLU C 2 281 ? 121.612 143.450 119.199 1.00 142.36 ? 281 GLU C OE2 1 
ATOM 3976 N N   . SER C 2 282 ? 123.802 143.668 125.059 1.00 123.41 ? 282 SER C N   1 
ATOM 3977 C CA  . SER C 2 282 ? 124.008 144.920 125.775 1.00 119.15 ? 282 SER C CA  1 
ATOM 3978 C C   . SER C 2 282 ? 125.458 145.108 126.196 1.00 121.05 ? 282 SER C C   1 
ATOM 3979 O O   . SER C 2 282 ? 125.880 146.244 126.438 1.00 116.36 ? 282 SER C O   1 
ATOM 3980 C CB  . SER C 2 282 ? 123.100 144.982 127.004 1.00 116.92 ? 282 SER C CB  1 
ATOM 3981 O OG  . SER C 2 282 ? 121.734 144.922 126.632 1.00 121.91 ? 282 SER C OG  1 
ATOM 3982 N N   . GLU C 2 283 ? 126.227 144.023 126.285 1.00 124.06 ? 283 GLU C N   1 
ATOM 3983 C CA  . GLU C 2 283 ? 127.616 144.081 126.711 1.00 118.12 ? 283 GLU C CA  1 
ATOM 3984 C C   . GLU C 2 283 ? 128.600 144.198 125.558 1.00 116.39 ? 283 GLU C C   1 
ATOM 3985 O O   . GLU C 2 283 ? 129.794 144.392 125.806 1.00 112.83 ? 283 GLU C O   1 
ATOM 3986 C CB  . GLU C 2 283 ? 127.966 142.835 127.538 1.00 111.13 ? 283 GLU C CB  1 
ATOM 3987 C CG  . GLU C 2 283 ? 126.800 142.247 128.319 1.00 111.92 ? 283 GLU C CG  1 
ATOM 3988 C CD  . GLU C 2 283 ? 126.600 142.893 129.671 1.00 112.47 ? 283 GLU C CD  1 
ATOM 3989 O OE1 . GLU C 2 283 ? 127.554 143.507 130.186 1.00 106.23 ? 283 GLU C OE1 1 
ATOM 3990 O OE2 . GLU C 2 283 ? 125.485 142.783 130.222 1.00 122.82 ? 283 GLU C OE2 1 
ATOM 3991 N N   . ARG C 2 284 ? 128.142 144.088 124.312 1.00 119.77 ? 284 ARG C N   1 
ATOM 3992 C CA  . ARG C 2 284 ? 129.035 144.103 123.154 1.00 117.24 ? 284 ARG C CA  1 
ATOM 3993 C C   . ARG C 2 284 ? 128.940 145.465 122.481 1.00 115.05 ? 284 ARG C C   1 
ATOM 3994 O O   . ARG C 2 284 ? 128.127 145.684 121.583 1.00 117.50 ? 284 ARG C O   1 
ATOM 3995 C CB  . ARG C 2 284 ? 128.684 142.979 122.188 1.00 114.63 ? 284 ARG C CB  1 
ATOM 3996 C CG  . ARG C 2 284 ? 128.703 141.600 122.811 1.00 112.79 ? 284 ARG C CG  1 
ATOM 3997 C CD  . ARG C 2 284 ? 128.422 140.533 121.772 1.00 114.85 ? 284 ARG C CD  1 
ATOM 3998 N NE  . ARG C 2 284 ? 129.394 140.574 120.687 1.00 114.21 ? 284 ARG C NE  1 
ATOM 3999 C CZ  . ARG C 2 284 ? 129.430 139.711 119.682 1.00 114.50 ? 284 ARG C CZ  1 
ATOM 4000 N NH1 . ARG C 2 284 ? 128.560 138.720 119.590 1.00 120.04 ? 284 ARG C NH1 1 
ATOM 4001 N NH2 . ARG C 2 284 ? 130.365 139.846 118.745 1.00 108.76 ? 284 ARG C NH2 1 
ATOM 4002 N N   . SER C 2 285 ? 129.785 146.394 122.918 1.00 110.42 ? 285 SER C N   1 
ATOM 4003 C CA  . SER C 2 285 ? 129.833 147.718 122.317 1.00 111.90 ? 285 SER C CA  1 
ATOM 4004 C C   . SER C 2 285 ? 130.768 147.799 121.119 1.00 114.91 ? 285 SER C C   1 
ATOM 4005 O O   . SER C 2 285 ? 130.697 148.775 120.365 1.00 117.60 ? 285 SER C O   1 
ATOM 4006 C CB  . SER C 2 285 ? 130.251 148.758 123.359 1.00 110.75 ? 285 SER C CB  1 
ATOM 4007 O OG  . SER C 2 285 ? 129.301 148.836 124.405 1.00 110.74 ? 285 SER C OG  1 
ATOM 4008 N N   . MET C 2 286 ? 131.622 146.801 120.912 1.00 115.56 ? 286 MET C N   1 
ATOM 4009 C CA  . MET C 2 286 ? 132.580 146.811 119.818 1.00 118.48 ? 286 MET C CA  1 
ATOM 4010 C C   . MET C 2 286 ? 132.440 145.536 119.000 1.00 117.04 ? 286 MET C C   1 
ATOM 4011 O O   . MET C 2 286 ? 131.851 144.548 119.445 1.00 112.04 ? 286 MET C O   1 
ATOM 4012 C CB  . MET C 2 286 ? 134.020 146.948 120.332 1.00 123.45 ? 286 MET C CB  1 
ATOM 4013 C CG  . MET C 2 286 ? 134.283 148.228 121.104 1.00 127.68 ? 286 MET C CG  1 
ATOM 4014 S SD  . MET C 2 286 ? 135.929 148.281 121.842 1.00 136.16 ? 286 MET C SD  1 
ATOM 4015 C CE  . MET C 2 286 ? 136.966 148.210 120.386 1.00 125.30 ? 286 MET C CE  1 
ATOM 4016 N N   . THR C 2 287 ? 132.992 145.571 117.789 1.00 122.67 ? 287 THR C N   1 
ATOM 4017 C CA  . THR C 2 287 ? 132.963 144.412 116.906 1.00 125.81 ? 287 THR C CA  1 
ATOM 4018 C C   . THR C 2 287 ? 133.944 143.358 117.400 1.00 123.53 ? 287 THR C C   1 
ATOM 4019 O O   . THR C 2 287 ? 135.055 143.234 116.875 1.00 121.69 ? 287 THR C O   1 
ATOM 4020 C CB  . THR C 2 287 ? 133.292 144.815 115.468 1.00 127.29 ? 287 THR C CB  1 
ATOM 4021 O OG1 . THR C 2 287 ? 134.612 145.367 115.417 1.00 130.89 ? 287 THR C OG1 1 
ATOM 4022 C CG2 . THR C 2 287 ? 132.299 145.849 114.965 1.00 120.85 ? 287 THR C CG2 1 
ATOM 4023 N N   . MET C 2 288 ? 133.539 142.596 118.411 1.00 119.24 ? 288 MET C N   1 
ATOM 4024 C CA  . MET C 2 288 ? 134.435 141.631 119.028 1.00 112.75 ? 288 MET C CA  1 
ATOM 4025 C C   . MET C 2 288 ? 134.642 140.421 118.129 1.00 108.41 ? 288 MET C C   1 
ATOM 4026 O O   . MET C 2 288 ? 133.684 139.817 117.639 1.00 106.97 ? 288 MET C O   1 
ATOM 4027 C CB  . MET C 2 288 ? 133.872 141.185 120.375 1.00 109.85 ? 288 MET C CB  1 
ATOM 4028 C CG  . MET C 2 288 ? 133.518 142.327 121.304 1.00 114.04 ? 288 MET C CG  1 
ATOM 4029 S SD  . MET C 2 288 ? 132.621 141.768 122.760 1.00 114.59 ? 288 MET C SD  1 
ATOM 4030 C CE  . MET C 2 288 ? 132.540 143.284 123.699 1.00 104.94 ? 288 MET C CE  1 
ATOM 4031 N N   . THR C 2 289 ? 135.906 140.066 117.917 1.00 108.16 ? 289 THR C N   1 
ATOM 4032 C CA  . THR C 2 289 ? 136.269 138.840 117.224 1.00 108.58 ? 289 THR C CA  1 
ATOM 4033 C C   . THR C 2 289 ? 137.313 138.111 118.053 1.00 101.29 ? 289 THR C C   1 
ATOM 4034 O O   . THR C 2 289 ? 138.341 138.689 118.413 1.00 95.92  ? 289 THR C O   1 
ATOM 4035 C CB  . THR C 2 289 ? 136.820 139.112 115.817 1.00 114.65 ? 289 THR C CB  1 
ATOM 4036 O OG1 . THR C 2 289 ? 137.975 139.956 115.907 1.00 118.47 ? 289 THR C OG1 1 
ATOM 4037 C CG2 . THR C 2 289 ? 135.769 139.784 114.944 1.00 109.18 ? 289 THR C CG2 1 
ATOM 4038 N N   . LYS C 2 290 ? 137.046 136.846 118.352 1.00 98.60  ? 290 LYS C N   1 
ATOM 4039 C CA  . LYS C 2 290 ? 137.941 136.044 119.169 1.00 95.28  ? 290 LYS C CA  1 
ATOM 4040 C C   . LYS C 2 290 ? 138.984 135.356 118.298 1.00 92.32  ? 290 LYS C C   1 
ATOM 4041 O O   . LYS C 2 290 ? 138.794 135.151 117.097 1.00 94.30  ? 290 LYS C O   1 
ATOM 4042 C CB  . LYS C 2 290 ? 137.159 135.005 119.977 1.00 94.70  ? 290 LYS C CB  1 
ATOM 4043 C CG  . LYS C 2 290 ? 136.619 133.850 119.158 1.00 100.96 ? 290 LYS C CG  1 
ATOM 4044 C CD  . LYS C 2 290 ? 135.913 132.830 120.037 1.00 96.54  ? 290 LYS C CD  1 
ATOM 4045 C CE  . LYS C 2 290 ? 134.649 133.408 120.652 1.00 91.46  ? 290 LYS C CE  1 
ATOM 4046 N NZ  . LYS C 2 290 ? 133.888 132.399 121.438 1.00 82.71  ? 290 LYS C NZ  1 
ATOM 4047 N N   . LEU C 2 291 ? 140.102 135.004 118.926 1.00 86.42  ? 291 LEU C N   1 
ATOM 4048 C CA  . LEU C 2 291 ? 141.205 134.352 118.235 1.00 87.00  ? 291 LEU C CA  1 
ATOM 4049 C C   . LEU C 2 291 ? 141.946 133.503 119.251 1.00 86.12  ? 291 LEU C C   1 
ATOM 4050 O O   . LEU C 2 291 ? 142.322 134.003 120.314 1.00 87.63  ? 291 LEU C O   1 
ATOM 4051 C CB  . LEU C 2 291 ? 142.138 135.387 117.594 1.00 91.92  ? 291 LEU C CB  1 
ATOM 4052 C CG  . LEU C 2 291 ? 143.220 134.929 116.612 1.00 95.10  ? 291 LEU C CG  1 
ATOM 4053 C CD1 . LEU C 2 291 ? 143.514 136.037 115.616 1.00 97.51  ? 291 LEU C CD1 1 
ATOM 4054 C CD2 . LEU C 2 291 ? 144.493 134.526 117.338 1.00 91.04  ? 291 LEU C CD2 1 
ATOM 4055 N N   . VAL C 2 292 ? 142.157 132.231 118.929 1.00 82.93  ? 292 VAL C N   1 
ATOM 4056 C CA  . VAL C 2 292 ? 142.723 131.266 119.863 1.00 85.97  ? 292 VAL C CA  1 
ATOM 4057 C C   . VAL C 2 292 ? 144.071 130.798 119.337 1.00 89.10  ? 292 VAL C C   1 
ATOM 4058 O O   . VAL C 2 292 ? 144.185 130.391 118.176 1.00 97.03  ? 292 VAL C O   1 
ATOM 4059 C CB  . VAL C 2 292 ? 141.777 130.071 120.079 1.00 88.06  ? 292 VAL C CB  1 
ATOM 4060 C CG1 . VAL C 2 292 ? 142.419 129.046 120.998 1.00 81.76  ? 292 VAL C CG1 1 
ATOM 4061 C CG2 . VAL C 2 292 ? 140.452 130.548 120.645 1.00 87.99  ? 292 VAL C CG2 1 
ATOM 4062 N N   . ARG C 2 293 ? 145.089 130.860 120.193 1.00 88.40  ? 293 ARG C N   1 
ATOM 4063 C CA  . ARG C 2 293 ? 146.412 130.328 119.890 1.00 94.72  ? 293 ARG C CA  1 
ATOM 4064 C C   . ARG C 2 293 ? 146.975 129.708 121.157 1.00 96.57  ? 293 ARG C C   1 
ATOM 4065 O O   . ARG C 2 293 ? 147.177 130.410 122.151 1.00 95.29  ? 293 ARG C O   1 
ATOM 4066 C CB  . ARG C 2 293 ? 147.356 131.417 119.372 1.00 96.41  ? 293 ARG C CB  1 
ATOM 4067 C CG  . ARG C 2 293 ? 147.186 131.775 117.908 1.00 99.82  ? 293 ARG C CG  1 
ATOM 4068 C CD  . ARG C 2 293 ? 148.446 132.440 117.379 1.00 98.20  ? 293 ARG C CD  1 
ATOM 4069 N NE  . ARG C 2 293 ? 148.279 132.954 116.026 1.00 103.13 ? 293 ARG C NE  1 
ATOM 4070 C CZ  . ARG C 2 293 ? 148.014 134.220 115.735 1.00 106.24 ? 293 ARG C CZ  1 
ATOM 4071 N NH1 . ARG C 2 293 ? 147.877 135.131 116.683 1.00 106.02 ? 293 ARG C NH1 1 
ATOM 4072 N NH2 . ARG C 2 293 ? 147.885 134.580 114.462 1.00 104.36 ? 293 ARG C NH2 1 
ATOM 4073 N N   . ASP C 2 294 ? 147.245 128.405 121.119 1.00 101.64 ? 294 ASP C N   1 
ATOM 4074 C CA  . ASP C 2 294 ? 147.778 127.706 122.280 1.00 103.33 ? 294 ASP C CA  1 
ATOM 4075 C C   . ASP C 2 294 ? 149.279 127.888 122.445 1.00 104.86 ? 294 ASP C C   1 
ATOM 4076 O O   . ASP C 2 294 ? 149.855 127.331 123.385 1.00 105.85 ? 294 ASP C O   1 
ATOM 4077 C CB  . ASP C 2 294 ? 147.450 126.217 122.190 1.00 107.49 ? 294 ASP C CB  1 
ATOM 4078 C CG  . ASP C 2 294 ? 145.981 125.937 122.407 1.00 115.96 ? 294 ASP C CG  1 
ATOM 4079 O OD1 . ASP C 2 294 ? 145.275 126.839 122.902 1.00 110.68 ? 294 ASP C OD1 1 
ATOM 4080 O OD2 . ASP C 2 294 ? 145.532 124.817 122.088 1.00 125.06 ? 294 ASP C OD2 1 
ATOM 4081 N N   . ASP C 2 295 ? 149.919 128.645 121.559 1.00 106.04 ? 295 ASP C N   1 
ATOM 4082 C CA  . ASP C 2 295 ? 151.362 128.838 121.564 1.00 109.09 ? 295 ASP C CA  1 
ATOM 4083 C C   . ASP C 2 295 ? 151.807 130.038 122.389 1.00 107.64 ? 295 ASP C C   1 
ATOM 4084 O O   . ASP C 2 295 ? 153.003 130.344 122.412 1.00 110.32 ? 295 ASP C O   1 
ATOM 4085 C CB  . ASP C 2 295 ? 151.866 128.995 120.127 1.00 111.84 ? 295 ASP C CB  1 
ATOM 4086 C CG  . ASP C 2 295 ? 151.153 130.107 119.380 1.00 108.96 ? 295 ASP C CG  1 
ATOM 4087 O OD1 . ASP C 2 295 ? 151.564 131.278 119.517 1.00 108.90 ? 295 ASP C OD1 1 
ATOM 4088 O OD2 . ASP C 2 295 ? 150.176 129.811 118.663 1.00 106.03 ? 295 ASP C OD2 1 
ATOM 4089 N N   . ILE C 2 296 ? 150.888 130.720 123.057 1.00 101.69 ? 296 ILE C N   1 
ATOM 4090 C CA  . ILE C 2 296 ? 151.240 131.952 123.769 1.00 98.25  ? 296 ILE C CA  1 
ATOM 4091 C C   . ILE C 2 296 ? 152.099 131.611 124.982 1.00 96.16  ? 296 ILE C C   1 
ATOM 4092 O O   . ILE C 2 296 ? 151.731 130.724 125.770 1.00 93.55  ? 296 ILE C O   1 
ATOM 4093 C CB  . ILE C 2 296 ? 149.976 132.705 124.174 1.00 88.31  ? 296 ILE C CB  1 
ATOM 4094 C CG1 . ILE C 2 296 ? 149.196 133.108 122.925 1.00 84.29  ? 296 ILE C CG1 1 
ATOM 4095 C CG2 . ILE C 2 296 ? 150.317 133.928 124.987 1.00 84.46  ? 296 ILE C CG2 1 
ATOM 4096 C CD1 . ILE C 2 296 ? 148.094 134.081 123.193 1.00 76.18  ? 296 ILE C CD1 1 
ATOM 4097 N N   . PRO C 2 297 ? 153.242 132.273 125.173 1.00 99.46  ? 297 PRO C N   1 
ATOM 4098 C CA  . PRO C 2 297 ? 154.116 131.941 126.308 1.00 102.32 ? 297 PRO C CA  1 
ATOM 4099 C C   . PRO C 2 297 ? 153.570 132.451 127.631 1.00 101.76 ? 297 PRO C C   1 
ATOM 4100 O O   . PRO C 2 297 ? 152.466 133.003 127.669 1.00 103.14 ? 297 PRO C O   1 
ATOM 4101 C CB  . PRO C 2 297 ? 155.431 132.632 125.941 1.00 107.76 ? 297 PRO C CB  1 
ATOM 4102 C CG  . PRO C 2 297 ? 155.014 133.787 125.096 1.00 108.10 ? 297 PRO C CG  1 
ATOM 4103 C CD  . PRO C 2 297 ? 153.814 133.326 124.318 1.00 100.54 ? 297 PRO C CD  1 
ATOM 4104 N N   . SER C 2 298 ? 154.316 132.277 128.720 1.00 105.22 ? 298 SER C N   1 
ATOM 4105 C CA  . SER C 2 298 ? 153.797 132.612 130.043 1.00 112.15 ? 298 SER C CA  1 
ATOM 4106 C C   . SER C 2 298 ? 154.840 133.351 130.883 1.00 115.92 ? 298 SER C C   1 
ATOM 4107 O O   . SER C 2 298 ? 155.000 133.097 132.077 1.00 114.19 ? 298 SER C O   1 
ATOM 4108 C CB  . SER C 2 298 ? 153.309 131.353 130.759 1.00 106.65 ? 298 SER C CB  1 
ATOM 4109 O OG  . SER C 2 298 ? 154.383 130.470 131.028 1.00 110.85 ? 298 SER C OG  1 
ATOM 4110 N N   . THR C 2 299 ? 155.559 134.293 130.274 1.00 114.11 ? 299 THR C N   1 
ATOM 4111 C CA  . THR C 2 299 ? 156.470 135.152 131.020 1.00 117.79 ? 299 THR C CA  1 
ATOM 4112 C C   . THR C 2 299 ? 156.338 136.577 130.507 1.00 117.98 ? 299 THR C C   1 
ATOM 4113 O O   . THR C 2 299 ? 155.836 136.821 129.408 1.00 114.97 ? 299 THR C O   1 
ATOM 4114 C CB  . THR C 2 299 ? 157.935 134.708 130.908 1.00 122.68 ? 299 THR C CB  1 
ATOM 4115 O OG1 . THR C 2 299 ? 158.371 134.827 129.550 1.00 123.52 ? 299 THR C OG1 1 
ATOM 4116 C CG2 . THR C 2 299 ? 158.129 133.273 131.386 1.00 121.60 ? 299 THR C CG2 1 
ATOM 4117 N N   . GLN C 2 300 ? 156.813 137.525 131.320 1.00 119.98 ? 300 GLN C N   1 
ATOM 4118 C CA  . GLN C 2 300 ? 156.764 138.932 130.931 1.00 116.36 ? 300 GLN C CA  1 
ATOM 4119 C C   . GLN C 2 300 ? 157.644 139.216 129.722 1.00 119.26 ? 300 GLN C C   1 
ATOM 4120 O O   . GLN C 2 300 ? 157.312 140.078 128.900 1.00 114.01 ? 300 GLN C O   1 
ATOM 4121 C CB  . GLN C 2 300 ? 157.185 139.815 132.106 1.00 110.85 ? 300 GLN C CB  1 
ATOM 4122 C CG  . GLN C 2 300 ? 156.997 141.307 131.875 1.00 108.74 ? 300 GLN C CG  1 
ATOM 4123 C CD  . GLN C 2 300 ? 158.199 141.968 131.241 1.00 115.35 ? 300 GLN C CD  1 
ATOM 4124 O OE1 . GLN C 2 300 ? 159.267 141.369 131.141 1.00 118.09 ? 300 GLN C OE1 1 
ATOM 4125 N NE2 . GLN C 2 300 ? 158.031 143.212 130.809 1.00 118.13 ? 300 GLN C NE2 1 
ATOM 4126 N N   . GLU C 2 301 ? 158.769 138.514 129.599 1.00 121.29 ? 301 GLU C N   1 
ATOM 4127 C CA  . GLU C 2 301 ? 159.723 138.768 128.514 1.00 118.21 ? 301 GLU C CA  1 
ATOM 4128 C C   . GLU C 2 301 ? 159.249 138.110 127.222 1.00 116.32 ? 301 GLU C C   1 
ATOM 4129 O O   . GLU C 2 301 ? 159.202 138.751 126.169 1.00 116.65 ? 301 GLU C O   1 
ATOM 4130 C CB  . GLU C 2 301 ? 161.115 138.274 128.911 1.00 117.77 ? 301 GLU C CB  1 
ATOM 4131 C CG  . GLU C 2 301 ? 161.641 138.869 130.206 1.00 120.60 ? 301 GLU C CG  1 
ATOM 4132 C CD  . GLU C 2 301 ? 161.972 140.341 130.081 1.00 118.83 ? 301 GLU C CD  1 
ATOM 4133 O OE1 . GLU C 2 301 ? 162.092 140.832 128.939 1.00 114.38 ? 301 GLU C OE1 1 
ATOM 4134 O OE2 . GLU C 2 301 ? 162.110 141.009 131.126 1.00 119.72 ? 301 GLU C OE2 1 
ATOM 4135 N N   . ASN C 2 302 ? 158.893 136.829 127.298 1.00 114.04 ? 302 ASN C N   1 
ATOM 4136 C CA  . ASN C 2 302 ? 158.524 136.071 126.110 1.00 113.34 ? 302 ASN C CA  1 
ATOM 4137 C C   . ASN C 2 302 ? 157.268 136.625 125.453 1.00 113.46 ? 302 ASN C C   1 
ATOM 4138 O O   . ASN C 2 302 ? 157.120 136.533 124.233 1.00 113.91 ? 302 ASN C O   1 
ATOM 4139 C CB  . ASN C 2 302 ? 158.332 134.595 126.456 1.00 112.36 ? 302 ASN C CB  1 
ATOM 4140 C CG  . ASN C 2 302 ? 159.615 133.932 126.915 1.00 118.97 ? 302 ASN C CG  1 
ATOM 4141 O OD1 . ASN C 2 302 ? 159.595 133.019 127.741 1.00 120.99 ? 302 ASN C OD1 1 
ATOM 4142 N ND2 . ASN C 2 302 ? 160.740 134.389 126.379 1.00 121.58 ? 302 ASN C ND2 1 
ATOM 4143 N N   . LEU C 2 303 ? 156.351 137.187 126.245 1.00 115.85 ? 303 LEU C N   1 
ATOM 4144 C CA  . LEU C 2 303 ? 155.108 137.708 125.681 1.00 115.17 ? 303 LEU C CA  1 
ATOM 4145 C C   . LEU C 2 303 ? 155.366 138.898 124.763 1.00 116.34 ? 303 LEU C C   1 
ATOM 4146 O O   . LEU C 2 303 ? 154.721 139.035 123.715 1.00 116.15 ? 303 LEU C O   1 
ATOM 4147 C CB  . LEU C 2 303 ? 154.141 138.081 126.803 1.00 105.63 ? 303 LEU C CB  1 
ATOM 4148 C CG  . LEU C 2 303 ? 153.420 136.878 127.412 1.00 98.88  ? 303 LEU C CG  1 
ATOM 4149 C CD1 . LEU C 2 303 ? 152.586 137.276 128.613 1.00 94.06  ? 303 LEU C CD1 1 
ATOM 4150 C CD2 . LEU C 2 303 ? 152.557 136.233 126.363 1.00 95.83  ? 303 LEU C CD2 1 
ATOM 4151 N N   . MET C 2 304 ? 156.302 139.770 125.140 1.00 118.28 ? 304 MET C N   1 
ATOM 4152 C CA  . MET C 2 304 ? 156.671 140.880 124.268 1.00 118.66 ? 304 MET C CA  1 
ATOM 4153 C C   . MET C 2 304 ? 157.223 140.365 122.944 1.00 121.53 ? 304 MET C C   1 
ATOM 4154 O O   . MET C 2 304 ? 156.886 140.880 121.871 1.00 122.99 ? 304 MET C O   1 
ATOM 4155 C CB  . MET C 2 304 ? 157.696 141.775 124.965 1.00 118.55 ? 304 MET C CB  1 
ATOM 4156 C CG  . MET C 2 304 ? 157.243 142.335 126.302 1.00 114.49 ? 304 MET C CG  1 
ATOM 4157 S SD  . MET C 2 304 ? 155.960 143.589 126.146 1.00 124.41 ? 304 MET C SD  1 
ATOM 4158 C CE  . MET C 2 304 ? 155.943 144.246 127.811 1.00 108.81 ? 304 MET C CE  1 
ATOM 4159 N N   . LYS C 2 305 ? 158.072 139.337 123.002 1.00 120.31 ? 305 LYS C N   1 
ATOM 4160 C CA  . LYS C 2 305 ? 158.624 138.766 121.779 1.00 122.99 ? 305 LYS C CA  1 
ATOM 4161 C C   . LYS C 2 305 ? 157.540 138.097 120.945 1.00 122.19 ? 305 LYS C C   1 
ATOM 4162 O O   . LYS C 2 305 ? 157.579 138.143 119.711 1.00 121.01 ? 305 LYS C O   1 
ATOM 4163 C CB  . LYS C 2 305 ? 159.735 137.772 122.120 1.00 122.02 ? 305 LYS C CB  1 
ATOM 4164 C CG  . LYS C 2 305 ? 160.461 137.209 120.909 1.00 121.86 ? 305 LYS C CG  1 
ATOM 4165 C CD  . LYS C 2 305 ? 161.596 136.289 121.322 1.00 118.53 ? 305 LYS C CD  1 
ATOM 4166 C CE  . LYS C 2 305 ? 162.274 135.679 120.109 1.00 124.16 ? 305 LYS C CE  1 
ATOM 4167 N NZ  . LYS C 2 305 ? 163.418 134.806 120.492 1.00 129.01 ? 305 LYS C NZ  1 
ATOM 4168 N N   . TRP C 2 306 ? 156.569 137.461 121.602 1.00 120.29 ? 306 TRP C N   1 
ATOM 4169 C CA  . TRP C 2 306 ? 155.459 136.849 120.880 1.00 118.34 ? 306 TRP C CA  1 
ATOM 4170 C C   . TRP C 2 306 ? 154.648 137.902 120.142 1.00 119.79 ? 306 TRP C C   1 
ATOM 4171 O O   . TRP C 2 306 ? 154.275 137.711 118.977 1.00 120.48 ? 306 TRP C O   1 
ATOM 4172 C CB  . TRP C 2 306 ? 154.570 136.072 121.852 1.00 112.14 ? 306 TRP C CB  1 
ATOM 4173 C CG  . TRP C 2 306 ? 153.545 135.216 121.184 1.00 110.85 ? 306 TRP C CG  1 
ATOM 4174 C CD1 . TRP C 2 306 ? 153.636 133.881 120.931 1.00 108.84 ? 306 TRP C CD1 1 
ATOM 4175 C CD2 . TRP C 2 306 ? 152.273 135.634 120.678 1.00 111.80 ? 306 TRP C CD2 1 
ATOM 4176 N NE1 . TRP C 2 306 ? 152.500 133.440 120.300 1.00 111.94 ? 306 TRP C NE1 1 
ATOM 4177 C CE2 . TRP C 2 306 ? 151.648 134.498 120.133 1.00 110.35 ? 306 TRP C CE2 1 
ATOM 4178 C CE3 . TRP C 2 306 ? 151.603 136.858 120.633 1.00 108.71 ? 306 TRP C CE3 1 
ATOM 4179 C CZ2 . TRP C 2 306 ? 150.388 134.550 119.551 1.00 105.45 ? 306 TRP C CZ2 1 
ATOM 4180 C CZ3 . TRP C 2 306 ? 150.353 136.908 120.054 1.00 105.13 ? 306 TRP C CZ3 1 
ATOM 4181 C CH2 . TRP C 2 306 ? 149.757 135.761 119.522 1.00 105.75 ? 306 TRP C CH2 1 
ATOM 4182 N N   . ALA C 2 307 ? 154.369 139.025 120.805 1.00 121.58 ? 307 ALA C N   1 
ATOM 4183 C CA  . ALA C 2 307 ? 153.665 140.117 120.144 1.00 121.67 ? 307 ALA C CA  1 
ATOM 4184 C C   . ALA C 2 307 ? 154.483 140.677 118.988 1.00 124.88 ? 307 ALA C C   1 
ATOM 4185 O O   . ALA C 2 307 ? 153.934 141.008 117.930 1.00 120.88 ? 307 ALA C O   1 
ATOM 4186 C CB  . ALA C 2 307 ? 153.336 141.216 121.151 1.00 121.06 ? 307 ALA C CB  1 
ATOM 4187 N N   . LEU C 2 308 ? 155.799 140.796 119.176 1.00 129.18 ? 308 LEU C N   1 
ATOM 4188 C CA  . LEU C 2 308 ? 156.664 141.273 118.102 1.00 128.60 ? 308 LEU C CA  1 
ATOM 4189 C C   . LEU C 2 308 ? 156.616 140.343 116.897 1.00 127.07 ? 308 LEU C C   1 
ATOM 4190 O O   . LEU C 2 308 ? 156.538 140.799 115.750 1.00 127.01 ? 308 LEU C O   1 
ATOM 4191 C CB  . LEU C 2 308 ? 158.097 141.413 118.617 1.00 125.73 ? 308 LEU C CB  1 
ATOM 4192 C CG  . LEU C 2 308 ? 159.228 141.468 117.587 1.00 128.47 ? 308 LEU C CG  1 
ATOM 4193 C CD1 . LEU C 2 308 ? 159.157 142.737 116.752 1.00 129.88 ? 308 LEU C CD1 1 
ATOM 4194 C CD2 . LEU C 2 308 ? 160.580 141.350 118.276 1.00 123.84 ? 308 LEU C CD2 1 
ATOM 4195 N N   . ASP C 2 309 ? 156.657 139.033 117.139 1.00 125.20 ? 309 ASP C N   1 
ATOM 4196 C CA  . ASP C 2 309 ? 156.672 138.071 116.043 1.00 127.09 ? 309 ASP C CA  1 
ATOM 4197 C C   . ASP C 2 309 ? 155.328 138.014 115.328 1.00 125.26 ? 309 ASP C C   1 
ATOM 4198 O O   . ASP C 2 309 ? 155.280 137.937 114.095 1.00 126.10 ? 309 ASP C O   1 
ATOM 4199 C CB  . ASP C 2 309 ? 157.056 136.688 116.568 1.00 128.81 ? 309 ASP C CB  1 
ATOM 4200 C CG  . ASP C 2 309 ? 156.875 135.600 115.530 1.00 130.95 ? 309 ASP C CG  1 
ATOM 4201 O OD1 . ASP C 2 309 ? 157.673 135.552 114.571 1.00 132.63 ? 309 ASP C OD1 1 
ATOM 4202 O OD2 . ASP C 2 309 ? 155.931 134.795 115.672 1.00 128.75 ? 309 ASP C OD2 1 
ATOM 4203 N N   . ASN C 2 310 ? 154.228 138.055 116.077 1.00 122.24 ? 310 ASN C N   1 
ATOM 4204 C CA  . ASN C 2 310 ? 152.908 137.869 115.486 1.00 118.89 ? 310 ASN C CA  1 
ATOM 4205 C C   . ASN C 2 310 ? 152.332 139.140 114.876 1.00 115.32 ? 310 ASN C C   1 
ATOM 4206 O O   . ASN C 2 310 ? 151.239 139.087 114.301 1.00 113.77 ? 310 ASN C O   1 
ATOM 4207 C CB  . ASN C 2 310 ? 151.943 137.311 116.532 1.00 117.37 ? 310 ASN C CB  1 
ATOM 4208 C CG  . ASN C 2 310 ? 152.190 135.848 116.823 1.00 114.86 ? 310 ASN C CG  1 
ATOM 4209 O OD1 . ASN C 2 310 ? 153.100 135.498 117.573 1.00 118.84 ? 310 ASN C OD1 1 
ATOM 4210 N ND2 . ASN C 2 310 ? 151.380 134.981 116.227 1.00 109.20 ? 310 ASN C ND2 1 
ATOM 4211 N N   . GLY C 2 311 ? 153.025 140.269 114.979 1.00 115.07 ? 311 GLY C N   1 
ATOM 4212 C CA  . GLY C 2 311 ? 152.563 141.492 114.361 1.00 118.29 ? 311 GLY C CA  1 
ATOM 4213 C C   . GLY C 2 311 ? 151.549 142.281 115.156 1.00 123.69 ? 311 GLY C C   1 
ATOM 4214 O O   . GLY C 2 311 ? 151.063 143.306 114.661 1.00 124.95 ? 311 GLY C O   1 
ATOM 4215 N N   . TYR C 2 312 ? 151.208 141.844 116.369 1.00 125.42 ? 312 TYR C N   1 
ATOM 4216 C CA  . TYR C 2 312 ? 150.307 142.598 117.239 1.00 123.42 ? 312 TYR C CA  1 
ATOM 4217 C C   . TYR C 2 312 ? 151.117 143.671 117.966 1.00 122.78 ? 312 TYR C C   1 
ATOM 4218 O O   . TYR C 2 312 ? 151.374 143.612 119.169 1.00 120.45 ? 312 TYR C O   1 
ATOM 4219 C CB  . TYR C 2 312 ? 149.594 141.662 118.202 1.00 117.05 ? 312 TYR C CB  1 
ATOM 4220 C CG  . TYR C 2 312 ? 148.697 140.675 117.498 1.00 115.18 ? 312 TYR C CG  1 
ATOM 4221 C CD1 . TYR C 2 312 ? 147.882 141.081 116.452 1.00 115.44 ? 312 TYR C CD1 1 
ATOM 4222 C CD2 . TYR C 2 312 ? 148.678 139.338 117.861 1.00 109.46 ? 312 TYR C CD2 1 
ATOM 4223 C CE1 . TYR C 2 312 ? 147.064 140.187 115.796 1.00 113.69 ? 312 TYR C CE1 1 
ATOM 4224 C CE2 . TYR C 2 312 ? 147.864 138.435 117.209 1.00 110.77 ? 312 TYR C CE2 1 
ATOM 4225 C CZ  . TYR C 2 312 ? 147.059 138.866 116.177 1.00 113.59 ? 312 TYR C CZ  1 
ATOM 4226 O OH  . TYR C 2 312 ? 146.243 137.975 115.520 1.00 111.26 ? 312 TYR C OH  1 
ATOM 4227 N N   . ARG C 2 313 ? 151.524 144.668 117.195 1.00 123.08 ? 313 ARG C N   1 
ATOM 4228 C CA  . ARG C 2 313 ? 152.450 145.704 117.615 1.00 119.28 ? 313 ARG C CA  1 
ATOM 4229 C C   . ARG C 2 313 ? 151.894 147.069 117.249 1.00 117.68 ? 313 ARG C C   1 
ATOM 4230 O O   . ARG C 2 313 ? 151.061 147.185 116.344 1.00 115.95 ? 313 ARG C O   1 
ATOM 4231 C CB  . ARG C 2 313 ? 153.820 145.504 116.950 1.00 118.93 ? 313 ARG C CB  1 
ATOM 4232 C CG  . ARG C 2 313 ? 154.907 145.045 117.901 1.00 121.86 ? 313 ARG C CG  1 
ATOM 4233 C CD  . ARG C 2 313 ? 156.181 144.677 117.160 1.00 132.18 ? 313 ARG C CD  1 
ATOM 4234 N NE  . ARG C 2 313 ? 156.690 145.764 116.331 1.00 141.14 ? 313 ARG C NE  1 
ATOM 4235 C CZ  . ARG C 2 313 ? 156.577 145.816 115.011 1.00 140.99 ? 313 ARG C CZ  1 
ATOM 4236 N NH1 . ARG C 2 313 ? 155.977 144.853 114.330 1.00 136.51 ? 313 ARG C NH1 1 
ATOM 4237 N NH2 . ARG C 2 313 ? 157.080 146.859 114.357 1.00 145.44 ? 313 ARG C NH2 1 
ATOM 4238 N N   . PRO C 2 314 ? 152.331 148.133 117.940 1.00 119.55 ? 314 PRO C N   1 
ATOM 4239 C CA  . PRO C 2 314 ? 153.240 148.157 119.098 1.00 115.84 ? 314 PRO C CA  1 
ATOM 4240 C C   . PRO C 2 314 ? 152.531 147.741 120.379 1.00 114.38 ? 314 PRO C C   1 
ATOM 4241 O O   . PRO C 2 314 ? 151.324 147.913 120.502 1.00 112.51 ? 314 PRO C O   1 
ATOM 4242 C CB  . PRO C 2 314 ? 153.701 149.626 119.156 1.00 112.35 ? 314 PRO C CB  1 
ATOM 4243 C CG  . PRO C 2 314 ? 153.319 150.229 117.827 1.00 114.85 ? 314 PRO C CG  1 
ATOM 4244 C CD  . PRO C 2 314 ? 152.081 149.489 117.432 1.00 120.16 ? 314 PRO C CD  1 
ATOM 4245 N N   . VAL C 2 315 ? 153.255 147.197 121.351 1.00 113.97 ? 315 VAL C N   1 
ATOM 4246 C CA  . VAL C 2 315 ? 152.655 146.789 122.617 1.00 108.82 ? 315 VAL C CA  1 
ATOM 4247 C C   . VAL C 2 315 ? 152.370 148.035 123.443 1.00 109.77 ? 315 VAL C C   1 
ATOM 4248 O O   . VAL C 2 315 ? 153.294 148.743 123.856 1.00 111.94 ? 315 VAL C O   1 
ATOM 4249 C CB  . VAL C 2 315 ? 153.572 145.823 123.377 1.00 106.91 ? 315 VAL C CB  1 
ATOM 4250 C CG1 . VAL C 2 315 ? 152.989 145.503 124.737 1.00 102.94 ? 315 VAL C CG1 1 
ATOM 4251 C CG2 . VAL C 2 315 ? 153.775 144.557 122.573 1.00 109.96 ? 315 VAL C CG2 1 
ATOM 4252 N N   . THR C 2 316 ? 151.088 148.303 123.691 1.00 108.63 ? 316 THR C N   1 
ATOM 4253 C CA  . THR C 2 316 ? 150.692 149.505 124.417 1.00 107.14 ? 316 THR C CA  1 
ATOM 4254 C C   . THR C 2 316 ? 150.910 149.347 125.917 1.00 106.05 ? 316 THR C C   1 
ATOM 4255 O O   . THR C 2 316 ? 151.608 150.155 126.536 1.00 109.69 ? 316 THR C O   1 
ATOM 4256 C CB  . THR C 2 316 ? 149.228 149.852 124.126 1.00 103.10 ? 316 THR C CB  1 
ATOM 4257 O OG1 . THR C 2 316 ? 149.085 150.223 122.751 1.00 109.66 ? 316 THR C OG1 1 
ATOM 4258 C CG2 . THR C 2 316 ? 148.774 151.001 125.006 1.00 96.45  ? 316 THR C CG2 1 
ATOM 4259 N N   . SER C 2 317 ? 150.325 148.313 126.513 1.00 101.19 ? 317 SER C N   1 
ATOM 4260 C CA  . SER C 2 317 ? 150.422 148.113 127.950 1.00 97.58  ? 317 SER C CA  1 
ATOM 4261 C C   . SER C 2 317 ? 150.563 146.635 128.276 1.00 89.50  ? 317 SER C C   1 
ATOM 4262 O O   . SER C 2 317 ? 150.135 145.772 127.510 1.00 91.23  ? 317 SER C O   1 
ATOM 4263 C CB  . SER C 2 317 ? 149.202 148.685 128.671 1.00 97.24  ? 317 SER C CB  1 
ATOM 4264 O OG  . SER C 2 317 ? 149.262 148.410 130.057 1.00 99.81  ? 317 SER C OG  1 
ATOM 4265 N N   . TYR C 2 318 ? 151.163 146.355 129.429 1.00 84.77  ? 318 TYR C N   1 
ATOM 4266 C CA  . TYR C 2 318 ? 151.310 145.004 129.944 1.00 81.23  ? 318 TYR C CA  1 
ATOM 4267 C C   . TYR C 2 318 ? 150.941 145.004 131.417 1.00 84.24  ? 318 TYR C C   1 
ATOM 4268 O O   . TYR C 2 318 ? 151.311 145.923 132.151 1.00 91.91  ? 318 TYR C O   1 
ATOM 4269 C CB  . TYR C 2 318 ? 152.737 144.492 129.762 1.00 80.11  ? 318 TYR C CB  1 
ATOM 4270 C CG  . TYR C 2 318 ? 152.988 143.154 130.407 1.00 80.73  ? 318 TYR C CG  1 
ATOM 4271 C CD1 . TYR C 2 318 ? 152.764 141.977 129.713 1.00 78.63  ? 318 TYR C CD1 1 
ATOM 4272 C CD2 . TYR C 2 318 ? 153.453 143.068 131.708 1.00 91.72  ? 318 TYR C CD2 1 
ATOM 4273 C CE1 . TYR C 2 318 ? 152.991 140.753 130.298 1.00 88.69  ? 318 TYR C CE1 1 
ATOM 4274 C CE2 . TYR C 2 318 ? 153.679 141.849 132.303 1.00 98.19  ? 318 TYR C CE2 1 
ATOM 4275 C CZ  . TYR C 2 318 ? 153.451 140.695 131.593 1.00 97.97  ? 318 TYR C CZ  1 
ATOM 4276 O OH  . TYR C 2 318 ? 153.680 139.477 132.184 1.00 102.23 ? 318 TYR C OH  1 
ATOM 4277 N N   . THR C 2 319 ? 150.228 143.968 131.851 1.00 82.29  ? 319 THR C N   1 
ATOM 4278 C CA  . THR C 2 319 ? 149.742 143.889 133.223 1.00 82.40  ? 319 THR C CA  1 
ATOM 4279 C C   . THR C 2 319 ? 149.759 142.443 133.686 1.00 80.30  ? 319 THR C C   1 
ATOM 4280 O O   . THR C 2 319 ? 149.037 141.612 133.133 1.00 82.09  ? 319 THR C O   1 
ATOM 4281 C CB  . THR C 2 319 ? 148.328 144.457 133.335 1.00 82.93  ? 319 THR C CB  1 
ATOM 4282 O OG1 . THR C 2 319 ? 148.338 145.838 132.961 1.00 86.64  ? 319 THR C OG1 1 
ATOM 4283 C CG2 . THR C 2 319 ? 147.817 144.319 134.756 1.00 87.29  ? 319 THR C CG2 1 
ATOM 4284 N N   . MET C 2 320 ? 150.561 142.150 134.703 1.00 77.50  ? 320 MET C N   1 
ATOM 4285 C CA  . MET C 2 320 ? 150.651 140.821 135.294 1.00 79.66  ? 320 MET C CA  1 
ATOM 4286 C C   . MET C 2 320 ? 150.021 140.861 136.678 1.00 83.96  ? 320 MET C C   1 
ATOM 4287 O O   . MET C 2 320 ? 150.462 141.627 137.540 1.00 87.46  ? 320 MET C O   1 
ATOM 4288 C CB  . MET C 2 320 ? 152.104 140.361 135.390 1.00 86.26  ? 320 MET C CB  1 
ATOM 4289 C CG  . MET C 2 320 ? 152.299 139.102 136.216 1.00 87.81  ? 320 MET C CG  1 
ATOM 4290 S SD  . MET C 2 320 ? 154.014 138.865 136.721 1.00 114.42 ? 320 MET C SD  1 
ATOM 4291 C CE  . MET C 2 320 ? 154.846 138.862 135.135 1.00 110.38 ? 320 MET C CE  1 
ATOM 4292 N N   . ALA C 2 321 ? 149.002 140.032 136.892 1.00 80.91  ? 321 ALA C N   1 
ATOM 4293 C CA  . ALA C 2 321 ? 148.285 139.994 138.158 1.00 72.14  ? 321 ALA C CA  1 
ATOM 4294 C C   . ALA C 2 321 ? 148.450 138.624 138.796 1.00 75.38  ? 321 ALA C C   1 
ATOM 4295 O O   . ALA C 2 321 ? 147.999 137.622 138.217 1.00 77.11  ? 321 ALA C O   1 
ATOM 4296 C CB  . ALA C 2 321 ? 146.807 140.313 137.955 1.00 63.37  ? 321 ALA C CB  1 
ATOM 4297 N N   . PRO C 2 322 ? 149.086 138.522 139.965 1.00 77.56  ? 322 PRO C N   1 
ATOM 4298 C CA  . PRO C 2 322 ? 149.249 137.198 140.590 1.00 76.08  ? 322 PRO C CA  1 
ATOM 4299 C C   . PRO C 2 322 ? 147.933 136.514 140.917 1.00 74.96  ? 322 PRO C C   1 
ATOM 4300 O O   . PRO C 2 322 ? 147.835 135.286 140.814 1.00 76.14  ? 322 PRO C O   1 
ATOM 4301 C CB  . PRO C 2 322 ? 150.069 137.512 141.847 1.00 76.36  ? 322 PRO C CB  1 
ATOM 4302 C CG  . PRO C 2 322 ? 149.780 138.940 142.137 1.00 79.91  ? 322 PRO C CG  1 
ATOM 4303 C CD  . PRO C 2 322 ? 149.632 139.601 140.803 1.00 80.34  ? 322 PRO C CD  1 
ATOM 4304 N N   . VAL C 2 323 ? 146.914 137.273 141.312 1.00 70.84  ? 323 VAL C N   1 
ATOM 4305 C CA  . VAL C 2 323 ? 145.594 136.728 141.603 1.00 68.82  ? 323 VAL C CA  1 
ATOM 4306 C C   . VAL C 2 323 ? 144.554 137.803 141.318 1.00 71.64  ? 323 VAL C C   1 
ATOM 4307 O O   . VAL C 2 323 ? 144.646 138.914 141.849 1.00 75.67  ? 323 VAL C O   1 
ATOM 4308 C CB  . VAL C 2 323 ? 145.494 136.229 143.057 1.00 70.26  ? 323 VAL C CB  1 
ATOM 4309 C CG1 . VAL C 2 323 ? 144.079 135.781 143.370 1.00 73.17  ? 323 VAL C CG1 1 
ATOM 4310 C CG2 . VAL C 2 323 ? 146.477 135.104 143.303 1.00 74.27  ? 323 VAL C CG2 1 
ATOM 4311 N N   . ALA C 2 324 ? 143.574 137.473 140.479 1.00 70.53  ? 324 ALA C N   1 
ATOM 4312 C CA  . ALA C 2 324 ? 142.531 138.401 140.055 1.00 65.21  ? 324 ALA C CA  1 
ATOM 4313 C C   . ALA C 2 324 ? 141.522 137.637 139.211 1.00 63.49  ? 324 ALA C C   1 
ATOM 4314 O O   . ALA C 2 324 ? 141.811 136.547 138.714 1.00 67.60  ? 324 ALA C O   1 
ATOM 4315 C CB  . ALA C 2 324 ? 143.098 139.573 139.258 1.00 63.97  ? 324 ALA C CB  1 
ATOM 4316 N N   . ASN C 2 325 ? 140.318 138.205 139.086 1.00 56.40  ? 325 ASN C N   1 
ATOM 4317 C CA  . ASN C 2 325 ? 139.337 137.654 138.160 1.00 48.49  ? 325 ASN C CA  1 
ATOM 4318 C C   . ASN C 2 325 ? 138.319 138.677 137.664 1.00 47.90  ? 325 ASN C C   1 
ATOM 4319 O O   . ASN C 2 325 ? 137.239 138.277 137.219 1.00 54.46  ? 325 ASN C O   1 
ATOM 4320 C CB  . ASN C 2 325 ? 138.608 136.463 138.791 1.00 47.65  ? 325 ASN C CB  1 
ATOM 4321 C CG  . ASN C 2 325 ? 137.867 136.826 140.051 1.00 62.34  ? 325 ASN C CG  1 
ATOM 4322 O OD1 . ASN C 2 325 ? 137.690 137.996 140.367 1.00 71.69  ? 325 ASN C OD1 1 
ATOM 4323 N ND2 . ASN C 2 325 ? 137.420 135.815 140.781 1.00 68.56  ? 325 ASN C ND2 1 
ATOM 4324 N N   . ARG C 2 326 ? 138.597 139.972 137.763 1.00 45.21  ? 326 ARG C N   1 
ATOM 4325 C CA  . ARG C 2 326 ? 137.649 141.001 137.343 1.00 52.31  ? 326 ARG C CA  1 
ATOM 4326 C C   . ARG C 2 326 ? 138.388 142.172 136.700 1.00 58.58  ? 326 ARG C C   1 
ATOM 4327 O O   . ARG C 2 326 ? 138.237 143.325 137.101 1.00 69.35  ? 326 ARG C O   1 
ATOM 4328 C CB  . ARG C 2 326 ? 136.789 141.442 138.528 1.00 62.22  ? 326 ARG C CB  1 
ATOM 4329 C CG  . ARG C 2 326 ? 135.632 142.387 138.204 1.00 63.09  ? 326 ARG C CG  1 
ATOM 4330 C CD  . ARG C 2 326 ? 134.821 141.900 137.034 1.00 63.80  ? 326 ARG C CD  1 
ATOM 4331 N NE  . ARG C 2 326 ? 133.855 142.900 136.603 1.00 74.39  ? 326 ARG C NE  1 
ATOM 4332 C CZ  . ARG C 2 326 ? 132.546 142.787 136.759 1.00 82.82  ? 326 ARG C CZ  1 
ATOM 4333 N NH1 . ARG C 2 326 ? 132.008 141.715 137.316 1.00 84.93  ? 326 ARG C NH1 1 
ATOM 4334 N NH2 . ARG C 2 326 ? 131.755 143.770 136.341 1.00 82.74  ? 326 ARG C NH2 1 
ATOM 4335 N N   . PHE C 2 327 ? 139.232 141.884 135.714 1.00 54.42  ? 327 PHE C N   1 
ATOM 4336 C CA  . PHE C 2 327 ? 140.050 142.927 135.104 1.00 57.71  ? 327 PHE C CA  1 
ATOM 4337 C C   . PHE C 2 327 ? 139.192 144.061 134.555 1.00 64.71  ? 327 PHE C C   1 
ATOM 4338 O O   . PHE C 2 327 ? 138.133 143.831 133.968 1.00 64.66  ? 327 PHE C O   1 
ATOM 4339 C CB  . PHE C 2 327 ? 140.912 142.337 133.990 1.00 55.24  ? 327 PHE C CB  1 
ATOM 4340 C CG  . PHE C 2 327 ? 142.029 141.480 134.488 1.00 54.29  ? 327 PHE C CG  1 
ATOM 4341 C CD1 . PHE C 2 327 ? 143.245 142.037 134.820 1.00 59.44  ? 327 PHE C CD1 1 
ATOM 4342 C CD2 . PHE C 2 327 ? 141.862 140.119 134.630 1.00 56.20  ? 327 PHE C CD2 1 
ATOM 4343 C CE1 . PHE C 2 327 ? 144.272 141.253 135.285 1.00 62.24  ? 327 PHE C CE1 1 
ATOM 4344 C CE2 . PHE C 2 327 ? 142.887 139.332 135.092 1.00 55.89  ? 327 PHE C CE2 1 
ATOM 4345 C CZ  . PHE C 2 327 ? 144.092 139.900 135.419 1.00 58.92  ? 327 PHE C CZ  1 
ATOM 4346 N N   . HIS C 2 328 ? 139.649 145.290 134.769 1.00 69.64  ? 328 HIS C N   1 
ATOM 4347 C CA  . HIS C 2 328 ? 138.985 146.495 134.289 1.00 71.98  ? 328 HIS C CA  1 
ATOM 4348 C C   . HIS C 2 328 ? 139.945 147.271 133.402 1.00 76.58  ? 328 HIS C C   1 
ATOM 4349 O O   . HIS C 2 328 ? 141.109 147.463 133.766 1.00 81.25  ? 328 HIS C O   1 
ATOM 4350 C CB  . HIS C 2 328 ? 138.527 147.374 135.456 1.00 78.80  ? 328 HIS C CB  1 
ATOM 4351 C CG  . HIS C 2 328 ? 137.232 146.945 136.072 1.00 79.92  ? 328 HIS C CG  1 
ATOM 4352 N ND1 . HIS C 2 328 ? 136.422 147.809 136.774 1.00 83.25  ? 328 HIS C ND1 1 
ATOM 4353 C CD2 . HIS C 2 328 ? 136.606 145.745 136.089 1.00 75.92  ? 328 HIS C CD2 1 
ATOM 4354 C CE1 . HIS C 2 328 ? 135.349 147.161 137.193 1.00 82.15  ? 328 HIS C CE1 1 
ATOM 4355 N NE2 . HIS C 2 328 ? 135.438 145.906 136.793 1.00 74.13  ? 328 HIS C NE2 1 
ATOM 4356 N N   . LEU C 2 329 ? 139.460 147.727 132.252 1.00 81.33  ? 329 LEU C N   1 
ATOM 4357 C CA  . LEU C 2 329 ? 140.292 148.408 131.261 1.00 90.88  ? 329 LEU C CA  1 
ATOM 4358 C C   . LEU C 2 329 ? 139.735 149.809 131.019 1.00 96.43  ? 329 LEU C C   1 
ATOM 4359 O O   . LEU C 2 329 ? 138.669 149.967 130.419 1.00 97.33  ? 329 LEU C O   1 
ATOM 4360 C CB  . LEU C 2 329 ? 140.357 147.599 129.968 1.00 85.97  ? 329 LEU C CB  1 
ATOM 4361 C CG  . LEU C 2 329 ? 141.213 148.146 128.828 1.00 84.26  ? 329 LEU C CG  1 
ATOM 4362 C CD1 . LEU C 2 329 ? 142.621 148.398 129.302 1.00 85.66  ? 329 LEU C CD1 1 
ATOM 4363 C CD2 . LEU C 2 329 ? 141.219 147.177 127.666 1.00 81.24  ? 329 LEU C CD2 1 
ATOM 4364 N N   . ARG C 2 330 ? 140.460 150.824 131.477 1.00 99.94  ? 330 ARG C N   1 
ATOM 4365 C CA  . ARG C 2 330 ? 140.051 152.215 131.331 1.00 107.48 ? 330 ARG C CA  1 
ATOM 4366 C C   . ARG C 2 330 ? 140.860 152.865 130.214 1.00 113.51 ? 330 ARG C C   1 
ATOM 4367 O O   . ARG C 2 330 ? 142.090 152.946 130.301 1.00 110.20 ? 330 ARG C O   1 
ATOM 4368 C CB  . ARG C 2 330 ? 140.241 152.976 132.643 1.00 104.54 ? 330 ARG C CB  1 
ATOM 4369 C CG  . ARG C 2 330 ? 139.423 152.431 133.802 1.00 105.75 ? 330 ARG C CG  1 
ATOM 4370 C CD  . ARG C 2 330 ? 137.939 152.685 133.594 1.00 110.32 ? 330 ARG C CD  1 
ATOM 4371 N NE  . ARG C 2 330 ? 137.122 152.029 134.608 1.00 109.68 ? 330 ARG C NE  1 
ATOM 4372 C CZ  . ARG C 2 330 ? 136.483 150.882 134.427 1.00 104.16 ? 330 ARG C CZ  1 
ATOM 4373 N NH1 . ARG C 2 330 ? 136.540 150.233 133.277 1.00 98.68  ? 330 ARG C NH1 1 
ATOM 4374 N NH2 . ARG C 2 330 ? 135.764 150.376 135.424 1.00 104.67 ? 330 ARG C NH2 1 
ATOM 4375 N N   . LEU C 2 331 ? 140.170 153.336 129.178 1.00 118.96 ? 331 LEU C N   1 
ATOM 4376 C CA  . LEU C 2 331 ? 140.815 153.985 128.043 1.00 123.09 ? 331 LEU C CA  1 
ATOM 4377 C C   . LEU C 2 331 ? 140.585 155.489 128.126 1.00 130.61 ? 331 LEU C C   1 
ATOM 4378 O O   . LEU C 2 331 ? 139.438 155.941 128.198 1.00 132.24 ? 331 LEU C O   1 
ATOM 4379 C CB  . LEU C 2 331 ? 140.274 153.429 126.727 1.00 120.91 ? 331 LEU C CB  1 
ATOM 4380 C CG  . LEU C 2 331 ? 140.565 151.956 126.439 1.00 112.61 ? 331 LEU C CG  1 
ATOM 4381 C CD1 . LEU C 2 331 ? 139.782 151.474 125.232 1.00 107.70 ? 331 LEU C CD1 1 
ATOM 4382 C CD2 . LEU C 2 331 ? 142.050 151.748 126.225 1.00 108.13 ? 331 LEU C CD2 1 
ATOM 4383 N N   . GLU C 2 332 ? 141.671 156.256 128.110 1.00 135.80 ? 332 GLU C N   1 
ATOM 4384 C CA  . GLU C 2 332 ? 141.618 157.707 128.218 1.00 142.26 ? 332 GLU C CA  1 
ATOM 4385 C C   . GLU C 2 332 ? 141.813 158.361 126.855 1.00 146.32 ? 332 GLU C C   1 
ATOM 4386 O O   . GLU C 2 332 ? 142.316 157.752 125.909 1.00 146.10 ? 332 GLU C O   1 
ATOM 4387 C CB  . GLU C 2 332 ? 142.680 158.219 129.195 1.00 139.08 ? 332 GLU C CB  1 
ATOM 4388 C CG  . GLU C 2 332 ? 142.435 157.826 130.640 1.00 138.11 ? 332 GLU C CG  1 
ATOM 4389 C CD  . GLU C 2 332 ? 143.520 158.329 131.571 1.00 137.10 ? 332 GLU C CD  1 
ATOM 4390 O OE1 . GLU C 2 332 ? 144.607 158.695 131.077 1.00 137.02 ? 332 GLU C OE1 1 
ATOM 4391 O OE2 . GLU C 2 332 ? 143.284 158.361 132.798 1.00 134.11 ? 332 GLU C OE2 1 
ATOM 4392 N N   . ASN C 2 333 ? 141.407 159.624 126.769 1.00 147.30 ? 333 ASN C N   1 
ATOM 4393 C CA  . ASN C 2 333 ? 141.529 160.383 125.530 1.00 149.52 ? 333 ASN C CA  1 
ATOM 4394 C C   . ASN C 2 333 ? 141.888 161.838 125.810 1.00 148.23 ? 333 ASN C C   1 
ATOM 4395 O O   . ASN C 2 333 ? 142.365 162.554 124.929 0.00 148.14 ? 333 ASN C O   1 
ATOM 4396 C CB  . ASN C 2 333 ? 140.231 160.305 124.723 1.00 151.42 ? 333 ASN C CB  1 
ATOM 4397 C CG  . ASN C 2 333 ? 139.847 158.881 124.374 1.00 149.06 ? 333 ASN C CG  1 
ATOM 4398 O OD1 . ASN C 2 333 ? 138.768 158.413 124.733 1.00 146.76 ? 333 ASN C OD1 1 
ATOM 4399 N ND2 . ASN C 2 333 ? 140.733 158.185 123.675 1.00 148.30 ? 333 ASN C ND2 1 
ATOM 4400 N N   . PHE D 3 7   ? 115.916 135.395 92.672  1.00 176.27 ? 10  PHE D N   1 
ATOM 4401 C CA  . PHE D 3 7   ? 116.427 134.273 91.892  1.00 176.27 ? 10  PHE D CA  1 
ATOM 4402 C C   . PHE D 3 7   ? 116.801 134.718 90.483  1.00 176.27 ? 10  PHE D C   1 
ATOM 4403 O O   . PHE D 3 7   ? 115.992 134.617 89.561  1.00 176.27 ? 10  PHE D O   1 
ATOM 4404 C CB  . PHE D 3 7   ? 115.395 133.146 91.835  1.00 176.27 ? 10  PHE D CB  1 
ATOM 4405 C CG  . PHE D 3 7   ? 114.953 132.661 93.186  1.00 176.27 ? 10  PHE D CG  1 
ATOM 4406 C CD1 . PHE D 3 7   ? 115.690 131.708 93.869  1.00 176.27 ? 10  PHE D CD1 1 
ATOM 4407 C CD2 . PHE D 3 7   ? 113.802 133.158 93.773  1.00 176.27 ? 10  PHE D CD2 1 
ATOM 4408 C CE1 . PHE D 3 7   ? 115.287 131.260 95.113  1.00 176.27 ? 10  PHE D CE1 1 
ATOM 4409 C CE2 . PHE D 3 7   ? 113.393 132.714 95.017  1.00 176.27 ? 10  PHE D CE2 1 
ATOM 4410 C CZ  . PHE D 3 7   ? 114.137 131.763 95.688  1.00 176.27 ? 10  PHE D CZ  1 
ATOM 4411 N N   . PRO D 3 8   ? 118.025 135.221 90.323  1.00 187.00 ? 11  PRO D N   1 
ATOM 4412 C CA  . PRO D 3 8   ? 118.466 135.681 89.001  1.00 187.00 ? 11  PRO D CA  1 
ATOM 4413 C C   . PRO D 3 8   ? 118.486 134.544 87.989  1.00 187.00 ? 11  PRO D C   1 
ATOM 4414 O O   . PRO D 3 8   ? 118.799 133.397 88.318  1.00 187.00 ? 11  PRO D O   1 
ATOM 4415 C CB  . PRO D 3 8   ? 119.874 136.224 89.267  1.00 187.00 ? 11  PRO D CB  1 
ATOM 4416 C CG  . PRO D 3 8   ? 119.901 136.521 90.733  1.00 187.00 ? 11  PRO D CG  1 
ATOM 4417 C CD  . PRO D 3 8   ? 119.033 135.478 91.364  1.00 187.00 ? 11  PRO D CD  1 
ATOM 4418 N N   . GLN D 3 9   ? 118.148 134.876 86.747  1.00 181.12 ? 12  GLN D N   1 
ATOM 4419 C CA  . GLN D 3 9   ? 118.075 133.877 85.692  1.00 181.12 ? 12  GLN D CA  1 
ATOM 4420 C C   . GLN D 3 9   ? 119.469 133.470 85.224  1.00 181.12 ? 12  GLN D C   1 
ATOM 4421 O O   . GLN D 3 9   ? 120.375 134.297 85.094  1.00 181.12 ? 12  GLN D O   1 
ATOM 4422 C CB  . GLN D 3 9   ? 117.259 134.410 84.514  1.00 181.12 ? 12  GLN D CB  1 
ATOM 4423 C CG  . GLN D 3 9   ? 117.228 133.486 83.310  1.00 181.12 ? 12  GLN D CG  1 
ATOM 4424 C CD  . GLN D 3 9   ? 116.240 133.931 82.252  1.00 181.12 ? 12  GLN D CD  1 
ATOM 4425 O OE1 . GLN D 3 9   ? 115.444 134.844 82.474  1.00 181.12 ? 12  GLN D OE1 1 
ATOM 4426 N NE2 . GLN D 3 9   ? 116.283 133.285 81.093  1.00 181.12 ? 12  GLN D NE2 1 
ATOM 4427 N N   . LEU D 3 10  ? 119.630 132.175 84.967  1.00 138.00 ? 13  LEU D N   1 
ATOM 4428 C CA  . LEU D 3 10  ? 120.875 131.618 84.460  1.00 138.00 ? 13  LEU D CA  1 
ATOM 4429 C C   . LEU D 3 10  ? 120.730 131.308 82.978  1.00 138.00 ? 13  LEU D C   1 
ATOM 4430 O O   . LEU D 3 10  ? 119.687 130.819 82.536  1.00 138.00 ? 13  LEU D O   1 
ATOM 4431 C CB  . LEU D 3 10  ? 121.263 130.345 85.215  1.00 138.00 ? 13  LEU D CB  1 
ATOM 4432 C CG  . LEU D 3 10  ? 121.660 130.443 86.690  1.00 138.00 ? 13  LEU D CG  1 
ATOM 4433 C CD1 . LEU D 3 10  ? 120.447 130.552 87.599  1.00 138.00 ? 13  LEU D CD1 1 
ATOM 4434 C CD2 . LEU D 3 10  ? 122.513 129.252 87.082  1.00 138.00 ? 13  LEU D CD2 1 
ATOM 4435 N N   . CYS D 3 11  ? 121.784 131.591 82.216  1.00 213.97 ? 14  CYS D N   1 
ATOM 4436 C CA  . CYS D 3 11  ? 121.768 131.365 80.779  1.00 213.97 ? 14  CYS D CA  1 
ATOM 4437 C C   . CYS D 3 11  ? 123.161 130.969 80.312  1.00 213.97 ? 14  CYS D C   1 
ATOM 4438 O O   . CYS D 3 11  ? 124.161 131.188 81.004  1.00 213.97 ? 14  CYS D O   1 
ATOM 4439 C CB  . CYS D 3 11  ? 121.304 132.608 80.005  1.00 213.97 ? 14  CYS D CB  1 
ATOM 4440 S SG  . CYS D 3 11  ? 119.651 133.233 80.395  1.00 213.97 ? 14  CYS D SG  1 
ATOM 4441 N N   . LYS D 3 12  ? 123.211 130.385 79.120  1.00 193.89 ? 15  LYS D N   1 
ATOM 4442 C CA  . LYS D 3 12  ? 124.469 130.128 78.437  1.00 193.89 ? 15  LYS D CA  1 
ATOM 4443 C C   . LYS D 3 12  ? 124.829 131.341 77.592  1.00 193.89 ? 15  LYS D C   1 
ATOM 4444 O O   . LYS D 3 12  ? 123.999 131.853 76.835  1.00 193.89 ? 15  LYS D O   1 
ATOM 4445 C CB  . LYS D 3 12  ? 124.366 128.881 77.558  1.00 193.89 ? 15  LYS D CB  1 
ATOM 4446 C CG  . LYS D 3 12  ? 123.604 127.730 78.198  1.00 193.89 ? 15  LYS D CG  1 
ATOM 4447 C CD  . LYS D 3 12  ? 124.270 127.257 79.479  1.00 193.89 ? 15  LYS D CD  1 
ATOM 4448 C CE  . LYS D 3 12  ? 125.612 126.609 79.196  1.00 193.89 ? 15  LYS D CE  1 
ATOM 4449 N NZ  . LYS D 3 12  ? 125.472 125.408 78.326  1.00 193.89 ? 15  LYS D NZ  1 
ATOM 4450 N N   . PHE D 3 13  ? 126.068 131.805 77.730  1.00 231.45 ? 16  PHE D N   1 
ATOM 4451 C CA  . PHE D 3 13  ? 126.509 133.048 77.106  1.00 231.45 ? 16  PHE D CA  1 
ATOM 4452 C C   . PHE D 3 13  ? 127.670 132.796 76.155  1.00 231.45 ? 16  PHE D C   1 
ATOM 4453 O O   . PHE D 3 13  ? 128.656 133.539 76.136  1.00 231.45 ? 16  PHE D O   1 
ATOM 4454 C CB  . PHE D 3 13  ? 126.889 134.080 78.166  1.00 231.45 ? 16  PHE D CB  1 
ATOM 4455 C CG  . PHE D 3 13  ? 126.439 135.477 77.841  1.00 231.45 ? 16  PHE D CG  1 
ATOM 4456 C CD1 . PHE D 3 13  ? 126.490 135.954 76.543  1.00 231.45 ? 16  PHE D CD1 1 
ATOM 4457 C CD2 . PHE D 3 13  ? 125.953 136.309 78.836  1.00 231.45 ? 16  PHE D CD2 1 
ATOM 4458 C CE1 . PHE D 3 13  ? 126.073 137.238 76.244  1.00 231.45 ? 16  PHE D CE1 1 
ATOM 4459 C CE2 . PHE D 3 13  ? 125.535 137.594 78.543  1.00 231.45 ? 16  PHE D CE2 1 
ATOM 4460 C CZ  . PHE D 3 13  ? 125.595 138.058 77.246  1.00 231.45 ? 16  PHE D CZ  1 
ATOM 4461 N N   . CYS D 3 14  ? 127.571 131.741 75.351  1.00 230.52 ? 17  CYS D N   1 
ATOM 4462 C CA  . CYS D 3 14  ? 128.585 131.455 74.345  1.00 230.52 ? 17  CYS D CA  1 
ATOM 4463 C C   . CYS D 3 14  ? 128.318 132.271 73.085  1.00 230.52 ? 17  CYS D C   1 
ATOM 4464 O O   . CYS D 3 14  ? 127.163 132.534 72.737  1.00 230.52 ? 17  CYS D O   1 
ATOM 4465 C CB  . CYS D 3 14  ? 128.609 129.963 74.013  1.00 230.52 ? 17  CYS D CB  1 
ATOM 4466 S SG  . CYS D 3 14  ? 129.384 128.919 75.269  1.00 230.52 ? 17  CYS D SG  1 
ATOM 4467 N N   . ASP D 3 15  ? 129.389 132.667 72.404  1.00 227.86 ? 18  ASP D N   1 
ATOM 4468 C CA  . ASP D 3 15  ? 129.277 133.422 71.163  1.00 227.86 ? 18  ASP D CA  1 
ATOM 4469 C C   . ASP D 3 15  ? 128.968 132.464 70.012  1.00 227.86 ? 18  ASP D C   1 
ATOM 4470 O O   . ASP D 3 15  ? 128.612 131.300 70.217  1.00 227.86 ? 18  ASP D O   1 
ATOM 4471 C CB  . ASP D 3 15  ? 130.550 134.227 70.916  1.00 227.86 ? 18  ASP D CB  1 
ATOM 4472 C CG  . ASP D 3 15  ? 130.760 135.316 71.949  1.00 227.86 ? 18  ASP D CG  1 
ATOM 4473 O OD1 . ASP D 3 15  ? 129.755 135.836 72.479  1.00 227.86 ? 18  ASP D OD1 1 
ATOM 4474 O OD2 . ASP D 3 15  ? 131.928 135.655 72.230  1.00 227.86 ? 18  ASP D OD2 1 
ATOM 4475 N N   . VAL D 3 16  ? 129.091 132.957 68.777  1.00 248.14 ? 19  VAL D N   1 
ATOM 4476 C CA  . VAL D 3 16  ? 128.812 132.124 67.614  1.00 248.14 ? 19  VAL D CA  1 
ATOM 4477 C C   . VAL D 3 16  ? 129.794 130.961 67.569  1.00 248.14 ? 19  VAL D C   1 
ATOM 4478 O O   . VAL D 3 16  ? 131.011 131.139 67.695  1.00 248.14 ? 19  VAL D O   1 
ATOM 4479 C CB  . VAL D 3 16  ? 128.865 132.966 66.326  1.00 248.14 ? 19  VAL D CB  1 
ATOM 4480 C CG1 . VAL D 3 16  ? 130.130 133.813 66.286  1.00 248.14 ? 19  VAL D CG1 1 
ATOM 4481 C CG2 . VAL D 3 16  ? 128.774 132.071 65.097  1.00 248.14 ? 19  VAL D CG2 1 
ATOM 4482 N N   . ARG D 3 17  ? 129.256 129.756 67.400  1.00 251.88 ? 20  ARG D N   1 
ATOM 4483 C CA  . ARG D 3 17  ? 130.054 128.537 67.389  1.00 251.88 ? 20  ARG D CA  1 
ATOM 4484 C C   . ARG D 3 17  ? 129.674 127.728 66.154  1.00 251.88 ? 20  ARG D C   1 
ATOM 4485 O O   . ARG D 3 17  ? 128.904 128.181 65.301  1.00 251.88 ? 20  ARG D O   1 
ATOM 4486 C CB  . ARG D 3 17  ? 129.851 127.743 68.686  1.00 251.88 ? 20  ARG D CB  1 
ATOM 4487 C CG  . ARG D 3 17  ? 130.367 128.441 69.934  1.00 251.88 ? 20  ARG D CG  1 
ATOM 4488 C CD  . ARG D 3 17  ? 131.884 128.519 69.934  1.00 251.88 ? 20  ARG D CD  1 
ATOM 4489 N NE  . ARG D 3 17  ? 132.494 127.195 69.922  1.00 251.88 ? 20  ARG D NE  1 
ATOM 4490 C CZ  . ARG D 3 17  ? 133.801 126.971 69.939  1.00 251.88 ? 20  ARG D CZ  1 
ATOM 4491 N NH1 . ARG D 3 17  ? 134.673 127.966 69.970  1.00 251.88 ? 20  ARG D NH1 1 
ATOM 4492 N NH2 . ARG D 3 17  ? 134.244 125.717 69.927  1.00 251.88 ? 20  ARG D NH2 1 
ATOM 4493 N N   . PHE D 3 18  ? 130.221 126.519 66.059  1.00 224.08 ? 21  PHE D N   1 
ATOM 4494 C CA  . PHE D 3 18  ? 129.948 125.625 64.944  1.00 224.08 ? 21  PHE D CA  1 
ATOM 4495 C C   . PHE D 3 18  ? 129.649 124.235 65.482  1.00 224.08 ? 21  PHE D C   1 
ATOM 4496 O O   . PHE D 3 18  ? 130.349 123.741 66.370  1.00 224.08 ? 21  PHE D O   1 
ATOM 4497 C CB  . PHE D 3 18  ? 131.128 125.572 63.966  1.00 224.08 ? 21  PHE D CB  1 
ATOM 4498 C CG  . PHE D 3 18  ? 131.611 126.926 63.526  1.00 224.08 ? 21  PHE D CG  1 
ATOM 4499 C CD1 . PHE D 3 18  ? 132.722 127.505 64.116  1.00 224.08 ? 21  PHE D CD1 1 
ATOM 4500 C CD2 . PHE D 3 18  ? 130.950 127.621 62.526  1.00 224.08 ? 21  PHE D CD2 1 
ATOM 4501 C CE1 . PHE D 3 18  ? 133.168 128.751 63.714  1.00 224.08 ? 21  PHE D CE1 1 
ATOM 4502 C CE2 . PHE D 3 18  ? 131.391 128.866 62.120  1.00 224.08 ? 21  PHE D CE2 1 
ATOM 4503 C CZ  . PHE D 3 18  ? 132.501 129.432 62.715  1.00 224.08 ? 21  PHE D CZ  1 
ATOM 4504 N N   . SER D 3 19  ? 128.609 123.610 64.942  1.00 248.13 ? 22  SER D N   1 
ATOM 4505 C CA  . SER D 3 19  ? 128.197 122.281 65.378  1.00 248.13 ? 22  SER D CA  1 
ATOM 4506 C C   . SER D 3 19  ? 127.597 121.554 64.178  1.00 248.13 ? 22  SER D C   1 
ATOM 4507 O O   . SER D 3 19  ? 127.732 122.001 63.035  1.00 248.13 ? 22  SER D O   1 
ATOM 4508 C CB  . SER D 3 19  ? 127.224 122.384 66.565  1.00 248.13 ? 22  SER D CB  1 
ATOM 4509 O OG  . SER D 3 19  ? 126.051 123.093 66.204  1.00 248.13 ? 22  SER D OG  1 
ATOM 4510 N N   . THR D 3 20  ? 126.934 120.427 64.438  1.00 268.39 ? 23  THR D N   1 
ATOM 4511 C CA  . THR D 3 20  ? 126.317 119.617 63.395  1.00 268.39 ? 23  THR D CA  1 
ATOM 4512 C C   . THR D 3 20  ? 124.804 119.514 63.560  1.00 268.39 ? 23  THR D C   1 
ATOM 4513 O O   . THR D 3 20  ? 124.218 118.477 63.233  1.00 268.39 ? 23  THR D O   1 
ATOM 4514 C CB  . THR D 3 20  ? 126.939 118.220 63.368  1.00 268.39 ? 23  THR D CB  1 
ATOM 4515 O OG1 . THR D 3 20  ? 126.751 117.585 64.639  1.00 268.39 ? 23  THR D OG1 1 
ATOM 4516 C CG2 . THR D 3 20  ? 128.428 118.305 63.064  1.00 268.39 ? 23  THR D CG2 1 
ATOM 4517 N N   . CYS D 3 21  ? 124.161 120.565 64.062  1.00 267.40 ? 24  CYS D N   1 
ATOM 4518 C CA  . CYS D 3 21  ? 122.713 120.557 64.245  1.00 267.40 ? 24  CYS D CA  1 
ATOM 4519 C C   . CYS D 3 21  ? 122.036 120.983 62.948  1.00 267.40 ? 24  CYS D C   1 
ATOM 4520 O O   . CYS D 3 21  ? 122.019 122.170 62.608  1.00 267.40 ? 24  CYS D O   1 
ATOM 4521 C CB  . CYS D 3 21  ? 122.320 121.484 65.392  1.00 267.40 ? 24  CYS D CB  1 
ATOM 4522 S SG  . CYS D 3 21  ? 123.206 121.201 66.944  1.00 267.40 ? 24  CYS D SG  1 
ATOM 4523 N N   . ASP D 3 22  ? 121.477 120.017 62.221  1.00 261.09 ? 25  ASP D N   1 
ATOM 4524 C CA  . ASP D 3 22  ? 120.771 120.307 60.979  1.00 261.09 ? 25  ASP D CA  1 
ATOM 4525 C C   . ASP D 3 22  ? 119.803 119.170 60.690  1.00 261.09 ? 25  ASP D C   1 
ATOM 4526 O O   . ASP D 3 22  ? 120.195 117.999 60.724  1.00 261.09 ? 25  ASP D O   1 
ATOM 4527 C CB  . ASP D 3 22  ? 121.749 120.495 59.811  1.00 261.09 ? 25  ASP D CB  1 
ATOM 4528 C CG  . ASP D 3 22  ? 122.674 119.308 59.625  1.00 261.09 ? 25  ASP D CG  1 
ATOM 4529 O OD1 . ASP D 3 22  ? 123.008 118.648 60.631  1.00 261.09 ? 25  ASP D OD1 1 
ATOM 4530 O OD2 . ASP D 3 22  ? 123.067 119.034 58.471  1.00 261.09 ? 25  ASP D OD2 1 
ATOM 4531 N N   . ASN D 3 23  ? 118.546 119.521 60.410  1.00 258.85 ? 26  ASN D N   1 
ATOM 4532 C CA  . ASN D 3 23  ? 117.489 118.544 60.139  1.00 258.85 ? 26  ASN D CA  1 
ATOM 4533 C C   . ASN D 3 23  ? 117.342 117.553 61.292  1.00 258.85 ? 26  ASN D C   1 
ATOM 4534 O O   . ASN D 3 23  ? 117.136 116.355 61.084  1.00 258.85 ? 26  ASN D O   1 
ATOM 4535 C CB  . ASN D 3 23  ? 117.735 117.811 58.818  1.00 258.85 ? 26  ASN D CB  1 
ATOM 4536 C CG  . ASN D 3 23  ? 117.770 118.751 57.628  1.00 258.85 ? 26  ASN D CG  1 
ATOM 4537 O OD1 . ASN D 3 23  ? 117.115 119.793 57.626  1.00 258.85 ? 26  ASN D OD1 1 
ATOM 4538 N ND2 . ASN D 3 23  ? 118.537 118.385 56.608  1.00 258.85 ? 26  ASN D ND2 1 
ATOM 4539 N N   . GLN D 3 24  ? 117.449 118.057 62.518  1.00 243.66 ? 27  GLN D N   1 
ATOM 4540 C CA  . GLN D 3 24  ? 117.334 117.248 63.723  1.00 243.66 ? 27  GLN D CA  1 
ATOM 4541 C C   . GLN D 3 24  ? 116.193 117.773 64.582  1.00 243.66 ? 27  GLN D C   1 
ATOM 4542 O O   . GLN D 3 24  ? 115.885 118.969 64.558  1.00 243.66 ? 27  GLN D O   1 
ATOM 4543 C CB  . GLN D 3 24  ? 118.640 117.259 64.526  1.00 243.66 ? 27  GLN D CB  1 
ATOM 4544 C CG  . GLN D 3 24  ? 119.867 116.827 63.736  1.00 243.66 ? 27  GLN D CG  1 
ATOM 4545 C CD  . GLN D 3 24  ? 119.815 115.371 63.312  1.00 243.66 ? 27  GLN D CD  1 
ATOM 4546 O OE1 . GLN D 3 24  ? 119.123 114.557 63.924  1.00 243.66 ? 27  GLN D OE1 1 
ATOM 4547 N NE2 . GLN D 3 24  ? 120.549 115.037 62.257  1.00 243.66 ? 27  GLN D NE2 1 
ATOM 4548 N N   . LYS D 3 25  ? 115.558 116.870 65.333  1.00 237.59 ? 28  LYS D N   1 
ATOM 4549 C CA  . LYS D 3 25  ? 114.466 117.271 66.212  1.00 237.59 ? 28  LYS D CA  1 
ATOM 4550 C C   . LYS D 3 25  ? 114.955 117.990 67.462  1.00 237.59 ? 28  LYS D C   1 
ATOM 4551 O O   . LYS D 3 25  ? 114.207 118.791 68.032  1.00 237.59 ? 28  LYS D O   1 
ATOM 4552 C CB  . LYS D 3 25  ? 113.633 116.051 66.608  1.00 237.59 ? 28  LYS D CB  1 
ATOM 4553 C CG  . LYS D 3 25  ? 112.892 115.403 65.450  1.00 237.59 ? 28  LYS D CG  1 
ATOM 4554 C CD  . LYS D 3 25  ? 112.039 114.238 65.924  1.00 237.59 ? 28  LYS D CD  1 
ATOM 4555 C CE  . LYS D 3 25  ? 111.234 113.643 64.780  1.00 237.59 ? 28  LYS D CE  1 
ATOM 4556 N NZ  . LYS D 3 25  ? 110.319 114.647 64.168  1.00 237.59 ? 28  LYS D NZ  1 
ATOM 4557 N N   . SER D 3 26  ? 116.183 117.724 67.901  1.00 273.62 ? 29  SER D N   1 
ATOM 4558 C CA  . SER D 3 26  ? 116.725 118.369 69.089  1.00 273.62 ? 29  SER D CA  1 
ATOM 4559 C C   . SER D 3 26  ? 118.244 118.341 69.017  1.00 273.62 ? 29  SER D C   1 
ATOM 4560 O O   . SER D 3 26  ? 118.830 117.492 68.341  1.00 273.62 ? 29  SER D O   1 
ATOM 4561 C CB  . SER D 3 26  ? 116.236 117.687 70.372  1.00 273.62 ? 29  SER D CB  1 
ATOM 4562 O OG  . SER D 3 26  ? 116.786 118.307 71.521  1.00 273.62 ? 29  SER D OG  1 
ATOM 4563 N N   . CYS D 3 27  ? 118.872 119.281 69.723  1.00 269.34 ? 30  CYS D N   1 
ATOM 4564 C CA  . CYS D 3 27  ? 120.323 119.386 69.763  1.00 269.34 ? 30  CYS D CA  1 
ATOM 4565 C C   . CYS D 3 27  ? 120.740 119.962 71.111  1.00 269.34 ? 30  CYS D C   1 
ATOM 4566 O O   . CYS D 3 27  ? 119.906 120.371 71.925  1.00 269.34 ? 30  CYS D O   1 
ATOM 4567 C CB  . CYS D 3 27  ? 120.850 120.249 68.609  1.00 269.34 ? 30  CYS D CB  1 
ATOM 4568 S SG  . CYS D 3 27  ? 122.305 119.576 67.767  1.00 269.34 ? 30  CYS D SG  1 
ATOM 4569 N N   . MET D 3 28  ? 122.049 120.003 71.341  1.00 246.00 ? 31  MET D N   1 
ATOM 4570 C CA  . MET D 3 28  ? 122.619 120.580 72.548  1.00 246.00 ? 31  MET D CA  1 
ATOM 4571 C C   . MET D 3 28  ? 123.508 121.756 72.170  1.00 246.00 ? 31  MET D C   1 
ATOM 4572 O O   . MET D 3 28  ? 124.287 121.674 71.215  1.00 246.00 ? 31  MET D O   1 
ATOM 4573 C CB  . MET D 3 28  ? 123.422 119.540 73.338  1.00 246.00 ? 31  MET D CB  1 
ATOM 4574 C CG  . MET D 3 28  ? 123.870 120.012 74.711  1.00 246.00 ? 31  MET D CG  1 
ATOM 4575 S SD  . MET D 3 28  ? 124.709 118.722 75.651  1.00 246.00 ? 31  MET D SD  1 
ATOM 4576 C CE  . MET D 3 28  ? 124.991 119.566 77.206  1.00 246.00 ? 31  MET D CE  1 
ATOM 4577 N N   . SER D 3 29  ? 123.381 122.853 72.921  1.00 229.05 ? 32  SER D N   1 
ATOM 4578 C CA  . SER D 3 29  ? 124.162 124.049 72.622  1.00 229.05 ? 32  SER D CA  1 
ATOM 4579 C C   . SER D 3 29  ? 125.655 123.805 72.789  1.00 229.05 ? 32  SER D C   1 
ATOM 4580 O O   . SER D 3 29  ? 126.468 124.495 72.163  1.00 229.05 ? 32  SER D O   1 
ATOM 4581 C CB  . SER D 3 29  ? 123.711 125.207 73.513  1.00 229.05 ? 32  SER D CB  1 
ATOM 4582 O OG  . SER D 3 29  ? 123.885 124.893 74.884  1.00 229.05 ? 32  SER D OG  1 
ATOM 4583 N N   . ASN D 3 30  ? 126.032 122.831 73.623  1.00 225.10 ? 33  ASN D N   1 
ATOM 4584 C CA  . ASN D 3 30  ? 127.435 122.499 73.879  1.00 225.10 ? 33  ASN D CA  1 
ATOM 4585 C C   . ASN D 3 30  ? 128.215 123.714 74.373  1.00 225.10 ? 33  ASN D C   1 
ATOM 4586 O O   . ASN D 3 30  ? 129.381 123.910 74.021  1.00 225.10 ? 33  ASN D O   1 
ATOM 4587 C CB  . ASN D 3 30  ? 128.099 121.897 72.637  1.00 225.10 ? 33  ASN D CB  1 
ATOM 4588 C CG  . ASN D 3 30  ? 127.422 120.623 72.175  1.00 225.10 ? 33  ASN D CG  1 
ATOM 4589 O OD1 . ASN D 3 30  ? 126.861 119.877 72.978  1.00 225.10 ? 33  ASN D OD1 1 
ATOM 4590 N ND2 . ASN D 3 30  ? 127.471 120.365 70.873  1.00 225.10 ? 33  ASN D ND2 1 
ATOM 4591 N N   . CYS D 3 31  ? 127.571 124.539 75.193  1.00 207.52 ? 34  CYS D N   1 
ATOM 4592 C CA  . CYS D 3 31  ? 128.200 125.728 75.751  1.00 207.52 ? 34  CYS D CA  1 
ATOM 4593 C C   . CYS D 3 31  ? 128.741 125.414 77.140  1.00 207.52 ? 34  CYS D C   1 
ATOM 4594 O O   . CYS D 3 31  ? 128.023 124.870 77.985  1.00 207.52 ? 34  CYS D O   1 
ATOM 4595 C CB  . CYS D 3 31  ? 127.203 126.887 75.814  1.00 207.52 ? 34  CYS D CB  1 
ATOM 4596 S SG  . CYS D 3 31  ? 127.865 128.415 76.519  1.00 207.52 ? 34  CYS D SG  1 
ATOM 4597 N N   . SER D 3 32  ? 130.008 125.750 77.366  1.00 219.39 ? 35  SER D N   1 
ATOM 4598 C CA  . SER D 3 32  ? 130.653 125.488 78.646  1.00 219.39 ? 35  SER D CA  1 
ATOM 4599 C C   . SER D 3 32  ? 130.537 126.650 79.621  1.00 219.39 ? 35  SER D C   1 
ATOM 4600 O O   . SER D 3 32  ? 131.090 126.568 80.723  1.00 219.39 ? 35  SER D O   1 
ATOM 4601 C CB  . SER D 3 32  ? 132.130 125.146 78.428  1.00 219.39 ? 35  SER D CB  1 
ATOM 4602 O OG  . SER D 3 32  ? 132.811 126.212 77.788  1.00 219.39 ? 35  SER D OG  1 
ATOM 4603 N N   . ILE D 3 33  ? 129.839 127.721 79.253  1.00 194.73 ? 36  ILE D N   1 
ATOM 4604 C CA  . ILE D 3 33  ? 129.724 128.915 80.083  1.00 194.73 ? 36  ILE D CA  1 
ATOM 4605 C C   . ILE D 3 33  ? 128.277 129.053 80.533  1.00 194.73 ? 36  ILE D C   1 
ATOM 4606 O O   . ILE D 3 33  ? 127.381 129.278 79.710  1.00 194.73 ? 36  ILE D O   1 
ATOM 4607 C CB  . ILE D 3 33  ? 130.189 130.172 79.332  1.00 194.73 ? 36  ILE D CB  1 
ATOM 4608 C CG1 . ILE D 3 33  ? 131.615 129.985 78.810  1.00 194.73 ? 36  ILE D CG1 1 
ATOM 4609 C CG2 . ILE D 3 33  ? 130.103 131.393 80.234  1.00 194.73 ? 36  ILE D CG2 1 
ATOM 4610 C CD1 . ILE D 3 33  ? 132.627 129.692 79.894  1.00 194.73 ? 36  ILE D CD1 1 
ATOM 4611 N N   . THR D 3 34  ? 128.051 128.923 81.838  1.00 118.56 ? 37  THR D N   1 
ATOM 4612 C CA  . THR D 3 34  ? 126.760 129.192 82.460  1.00 118.56 ? 37  THR D CA  1 
ATOM 4613 C C   . THR D 3 34  ? 126.933 130.408 83.356  1.00 118.56 ? 37  THR D C   1 
ATOM 4614 O O   . THR D 3 34  ? 127.874 130.459 84.155  1.00 118.56 ? 37  THR D O   1 
ATOM 4615 C CB  . THR D 3 34  ? 126.266 127.991 83.268  1.00 118.56 ? 37  THR D CB  1 
ATOM 4616 O OG1 . THR D 3 34  ? 126.183 126.842 82.417  1.00 118.56 ? 37  THR D OG1 1 
ATOM 4617 C CG2 . THR D 3 34  ? 124.895 128.278 83.854  1.00 118.56 ? 37  THR D CG2 1 
ATOM 4618 N N   . SER D 3 35  ? 126.046 131.390 83.219  1.00 94.02  ? 38  SER D N   1 
ATOM 4619 C CA  . SER D 3 35  ? 126.237 132.662 83.896  1.00 94.02  ? 38  SER D CA  1 
ATOM 4620 C C   . SER D 3 35  ? 124.911 133.345 84.186  1.00 94.02  ? 38  SER D C   1 
ATOM 4621 O O   . SER D 3 35  ? 123.896 133.069 83.542  1.00 94.02  ? 38  SER D O   1 
ATOM 4622 C CB  . SER D 3 35  ? 127.111 133.596 83.063  1.00 94.02  ? 38  SER D CB  1 
ATOM 4623 O OG  . SER D 3 35  ? 127.080 134.910 83.587  1.00 94.02  ? 38  SER D OG  1 
ATOM 4624 N N   . ILE D 3 36  ? 124.942 134.248 85.163  1.00 144.40 ? 39  ILE D N   1 
ATOM 4625 C CA  . ILE D 3 36  ? 123.802 135.109 85.444  1.00 144.40 ? 39  ILE D CA  1 
ATOM 4626 C C   . ILE D 3 36  ? 123.839 136.303 84.501  1.00 144.40 ? 39  ILE D C   1 
ATOM 4627 O O   . ILE D 3 36  ? 124.882 136.947 84.332  1.00 144.40 ? 39  ILE D O   1 
ATOM 4628 C CB  . ILE D 3 36  ? 123.824 135.558 86.912  1.00 144.40 ? 39  ILE D CB  1 
ATOM 4629 C CG1 . ILE D 3 36  ? 123.611 134.363 87.842  1.00 144.40 ? 39  ILE D CG1 1 
ATOM 4630 C CG2 . ILE D 3 36  ? 122.772 136.621 87.165  1.00 144.40 ? 39  ILE D CG2 1 
ATOM 4631 C CD1 . ILE D 3 36  ? 123.880 134.675 89.291  1.00 144.40 ? 39  ILE D CD1 1 
ATOM 4632 N N   . CYS D 3 37  ? 122.703 136.600 83.873  1.00 167.46 ? 40  CYS D N   1 
ATOM 4633 C CA  . CYS D 3 37  ? 122.619 137.787 83.034  1.00 167.46 ? 40  CYS D CA  1 
ATOM 4634 C C   . CYS D 3 37  ? 122.721 139.045 83.893  1.00 167.46 ? 40  CYS D C   1 
ATOM 4635 O O   . CYS D 3 37  ? 122.545 139.007 85.113  1.00 167.46 ? 40  CYS D O   1 
ATOM 4636 C CB  . CYS D 3 37  ? 121.313 137.796 82.237  1.00 167.46 ? 40  CYS D CB  1 
ATOM 4637 S SG  . CYS D 3 37  ? 120.990 136.310 81.244  1.00 167.46 ? 40  CYS D SG  1 
ATOM 4638 N N   . GLU D 3 38  ? 123.012 140.172 83.239  1.00 195.39 ? 41  GLU D N   1 
ATOM 4639 C CA  . GLU D 3 38  ? 123.222 141.421 83.966  1.00 195.39 ? 41  GLU D CA  1 
ATOM 4640 C C   . GLU D 3 38  ? 121.973 141.834 84.735  1.00 195.39 ? 41  GLU D C   1 
ATOM 4641 O O   . GLU D 3 38  ? 122.054 142.271 85.889  1.00 195.39 ? 41  GLU D O   1 
ATOM 4642 C CB  . GLU D 3 38  ? 123.649 142.525 82.998  1.00 195.39 ? 41  GLU D CB  1 
ATOM 4643 C CG  . GLU D 3 38  ? 124.988 142.271 82.327  1.00 195.39 ? 41  GLU D CG  1 
ATOM 4644 C CD  . GLU D 3 38  ? 125.408 143.406 81.416  1.00 195.39 ? 41  GLU D CD  1 
ATOM 4645 O OE1 . GLU D 3 38  ? 124.658 144.400 81.318  1.00 195.39 ? 41  GLU D OE1 1 
ATOM 4646 O OE2 . GLU D 3 38  ? 126.489 143.305 80.798  1.00 195.39 ? 41  GLU D OE2 1 
ATOM 4647 N N   . LYS D 3 39  ? 120.805 141.703 84.112  1.00 171.52 ? 42  LYS D N   1 
ATOM 4648 C CA  . LYS D 3 39  ? 119.568 142.038 84.795  1.00 171.52 ? 42  LYS D CA  1 
ATOM 4649 C C   . LYS D 3 39  ? 118.626 140.839 84.822  1.00 171.52 ? 42  LYS D C   1 
ATOM 4650 O O   . LYS D 3 39  ? 118.566 140.067 83.860  1.00 171.52 ? 42  LYS D O   1 
ATOM 4651 C CB  . LYS D 3 39  ? 118.860 143.218 84.119  1.00 171.52 ? 42  LYS D CB  1 
ATOM 4652 C CG  . LYS D 3 39  ? 119.649 144.515 84.158  1.00 171.52 ? 42  LYS D CG  1 
ATOM 4653 C CD  . LYS D 3 39  ? 118.848 145.666 83.573  1.00 171.52 ? 42  LYS D CD  1 
ATOM 4654 C CE  . LYS D 3 39  ? 119.629 146.968 83.632  1.00 171.52 ? 42  LYS D CE  1 
ATOM 4655 N NZ  . LYS D 3 39  ? 118.846 148.110 83.085  1.00 171.52 ? 42  LYS D NZ  1 
ATOM 4656 N N   . PRO D 3 40  ? 117.880 140.652 85.914  1.00 176.79 ? 43  PRO D N   1 
ATOM 4657 C CA  . PRO D 3 40  ? 116.920 139.537 85.961  1.00 176.79 ? 43  PRO D CA  1 
ATOM 4658 C C   . PRO D 3 40  ? 115.824 139.643 84.918  1.00 176.79 ? 43  PRO D C   1 
ATOM 4659 O O   . PRO D 3 40  ? 115.219 138.621 84.571  1.00 176.79 ? 43  PRO D O   1 
ATOM 4660 C CB  . PRO D 3 40  ? 116.353 139.622 87.386  1.00 176.79 ? 43  PRO D CB  1 
ATOM 4661 C CG  . PRO D 3 40  ? 116.573 141.043 87.797  1.00 176.79 ? 43  PRO D CG  1 
ATOM 4662 C CD  . PRO D 3 40  ? 117.862 141.454 87.149  1.00 176.79 ? 43  PRO D CD  1 
ATOM 4663 N N   . GLN D 3 41  ? 115.549 140.845 84.409  1.00 204.85 ? 44  GLN D N   1 
ATOM 4664 C CA  . GLN D 3 41  ? 114.560 141.000 83.351  1.00 204.85 ? 44  GLN D CA  1 
ATOM 4665 C C   . GLN D 3 41  ? 114.978 140.288 82.070  1.00 204.85 ? 44  GLN D C   1 
ATOM 4666 O O   . GLN D 3 41  ? 114.112 139.836 81.313  1.00 204.85 ? 44  GLN D O   1 
ATOM 4667 C CB  . GLN D 3 41  ? 114.322 142.487 83.079  1.00 204.85 ? 44  GLN D CB  1 
ATOM 4668 C CG  . GLN D 3 41  ? 113.249 142.780 82.042  1.00 204.85 ? 44  GLN D CG  1 
ATOM 4669 C CD  . GLN D 3 41  ? 113.040 144.265 81.824  1.00 204.85 ? 44  GLN D CD  1 
ATOM 4670 O OE1 . GLN D 3 41  ? 113.552 145.093 82.578  1.00 204.85 ? 44  GLN D OE1 1 
ATOM 4671 N NE2 . GLN D 3 41  ? 112.287 144.611 80.787  1.00 204.85 ? 44  GLN D NE2 1 
ATOM 4672 N N   . GLU D 3 42  ? 116.278 140.165 81.821  1.00 198.56 ? 45  GLU D N   1 
ATOM 4673 C CA  . GLU D 3 42  ? 116.791 139.527 80.619  1.00 198.56 ? 45  GLU D CA  1 
ATOM 4674 C C   . GLU D 3 42  ? 116.488 138.031 80.627  1.00 198.56 ? 45  GLU D C   1 
ATOM 4675 O O   . GLU D 3 42  ? 116.360 137.401 81.678  1.00 198.56 ? 45  GLU D O   1 
ATOM 4676 C CB  . GLU D 3 42  ? 118.297 139.758 80.490  1.00 198.56 ? 45  GLU D CB  1 
ATOM 4677 C CG  . GLU D 3 42  ? 118.703 141.223 80.484  1.00 198.56 ? 45  GLU D CG  1 
ATOM 4678 C CD  . GLU D 3 42  ? 120.204 141.411 80.382  1.00 198.56 ? 45  GLU D CD  1 
ATOM 4679 O OE1 . GLU D 3 42  ? 120.920 140.404 80.201  1.00 198.56 ? 45  GLU D OE1 1 
ATOM 4680 O OE2 . GLU D 3 42  ? 120.669 142.566 80.483  1.00 198.56 ? 45  GLU D OE2 1 
ATOM 4681 N N   . VAL D 3 43  ? 116.376 137.468 79.423  1.00 211.09 ? 46  VAL D N   1 
ATOM 4682 C CA  . VAL D 3 43  ? 116.066 136.061 79.223  1.00 211.09 ? 46  VAL D CA  1 
ATOM 4683 C C   . VAL D 3 43  ? 117.100 135.467 78.273  1.00 211.09 ? 46  VAL D C   1 
ATOM 4684 O O   . VAL D 3 43  ? 117.820 136.182 77.572  1.00 211.09 ? 46  VAL D O   1 
ATOM 4685 C CB  . VAL D 3 43  ? 114.641 135.848 78.671  1.00 211.09 ? 46  VAL D CB  1 
ATOM 4686 C CG1 . VAL D 3 43  ? 113.606 136.412 79.631  1.00 211.09 ? 46  VAL D CG1 1 
ATOM 4687 C CG2 . VAL D 3 43  ? 114.502 136.482 77.295  1.00 211.09 ? 46  VAL D CG2 1 
ATOM 4688 N N   . CYS D 3 44  ? 117.165 134.136 78.255  1.00 194.85 ? 47  CYS D N   1 
ATOM 4689 C CA  . CYS D 3 44  ? 118.100 133.429 77.391  1.00 194.85 ? 47  CYS D CA  1 
ATOM 4690 C C   . CYS D 3 44  ? 117.519 133.357 75.986  1.00 194.85 ? 47  CYS D C   1 
ATOM 4691 O O   . CYS D 3 44  ? 116.353 132.991 75.810  1.00 194.85 ? 47  CYS D O   1 
ATOM 4692 C CB  . CYS D 3 44  ? 118.378 132.018 77.911  1.00 194.85 ? 47  CYS D CB  1 
ATOM 4693 S SG  . CYS D 3 44  ? 118.377 131.810 79.708  1.00 194.85 ? 47  CYS D SG  1 
ATOM 4694 N N   . VAL D 3 45  ? 118.329 133.705 74.989  1.00 218.68 ? 48  VAL D N   1 
ATOM 4695 C CA  . VAL D 3 45  ? 117.907 133.697 73.595  1.00 218.68 ? 48  VAL D CA  1 
ATOM 4696 C C   . VAL D 3 45  ? 118.900 132.871 72.789  1.00 218.68 ? 48  VAL D C   1 
ATOM 4697 O O   . VAL D 3 45  ? 120.119 133.032 72.935  1.00 218.68 ? 48  VAL D O   1 
ATOM 4698 C CB  . VAL D 3 45  ? 117.781 135.125 73.024  1.00 218.68 ? 48  VAL D CB  1 
ATOM 4699 C CG1 . VAL D 3 45  ? 119.058 135.911 73.255  1.00 218.68 ? 48  VAL D CG1 1 
ATOM 4700 C CG2 . VAL D 3 45  ? 117.431 135.084 71.542  1.00 218.68 ? 48  VAL D CG2 1 
ATOM 4701 N N   . ALA D 3 46  ? 118.377 131.979 71.953  1.00 240.59 ? 49  ALA D N   1 
ATOM 4702 C CA  . ALA D 3 46  ? 119.178 131.143 71.073  1.00 240.59 ? 49  ALA D CA  1 
ATOM 4703 C C   . ALA D 3 46  ? 118.834 131.449 69.623  1.00 240.59 ? 49  ALA D C   1 
ATOM 4704 O O   . ALA D 3 46  ? 117.656 131.545 69.255  1.00 240.59 ? 49  ALA D O   1 
ATOM 4705 C CB  . ALA D 3 46  ? 118.961 129.655 71.363  1.00 240.59 ? 49  ALA D CB  1 
ATOM 4706 N N   . VAL D 3 47  ? 119.880 131.597 68.811  1.00 257.66 ? 50  VAL D N   1 
ATOM 4707 C CA  . VAL D 3 47  ? 119.780 131.982 67.409  1.00 257.66 ? 50  VAL D CA  1 
ATOM 4708 C C   . VAL D 3 47  ? 120.498 130.937 66.566  1.00 257.66 ? 50  VAL D C   1 
ATOM 4709 O O   . VAL D 3 47  ? 121.644 130.570 66.859  1.00 257.66 ? 50  VAL D O   1 
ATOM 4710 C CB  . VAL D 3 47  ? 120.368 133.386 67.169  1.00 257.66 ? 50  VAL D CB  1 
ATOM 4711 C CG1 . VAL D 3 47  ? 119.559 134.431 67.919  1.00 257.66 ? 50  VAL D CG1 1 
ATOM 4712 C CG2 . VAL D 3 47  ? 121.825 133.441 67.596  1.00 257.66 ? 50  VAL D CG2 1 
ATOM 4713 N N   . TRP D 3 48  ? 119.819 130.457 65.526  1.00 271.50 ? 51  TRP D N   1 
ATOM 4714 C CA  . TRP D 3 48  ? 120.350 129.484 64.580  1.00 271.50 ? 51  TRP D CA  1 
ATOM 4715 C C   . TRP D 3 48  ? 120.359 130.117 63.194  1.00 271.50 ? 51  TRP D C   1 
ATOM 4716 O O   . TRP D 3 48  ? 119.306 130.523 62.687  1.00 271.50 ? 51  TRP D O   1 
ATOM 4717 C CB  . TRP D 3 48  ? 119.507 128.209 64.590  1.00 271.50 ? 51  TRP D CB  1 
ATOM 4718 C CG  . TRP D 3 48  ? 120.039 127.106 63.732  1.00 271.50 ? 51  TRP D CG  1 
ATOM 4719 C CD1 . TRP D 3 48  ? 121.345 126.860 63.426  1.00 271.50 ? 51  TRP D CD1 1 
ATOM 4720 C CD2 . TRP D 3 48  ? 119.273 126.097 63.063  1.00 271.50 ? 51  TRP D CD2 1 
ATOM 4721 N NE1 . TRP D 3 48  ? 121.440 125.758 62.611  1.00 271.50 ? 51  TRP D NE1 1 
ATOM 4722 C CE2 . TRP D 3 48  ? 120.181 125.272 62.372  1.00 271.50 ? 51  TRP D CE2 1 
ATOM 4723 C CE3 . TRP D 3 48  ? 117.906 125.812 62.982  1.00 271.50 ? 51  TRP D CE3 1 
ATOM 4724 C CZ2 . TRP D 3 48  ? 119.768 124.181 61.611  1.00 271.50 ? 51  TRP D CZ2 1 
ATOM 4725 C CZ3 . TRP D 3 48  ? 117.498 124.729 62.224  1.00 271.50 ? 51  TRP D CZ3 1 
ATOM 4726 C CH2 . TRP D 3 48  ? 118.425 123.926 61.550  1.00 271.50 ? 51  TRP D CH2 1 
ATOM 4727 N N   . ARG D 3 49  ? 121.542 130.206 62.591  1.00 263.02 ? 52  ARG D N   1 
ATOM 4728 C CA  . ARG D 3 49  ? 121.719 130.863 61.297  1.00 263.02 ? 52  ARG D CA  1 
ATOM 4729 C C   . ARG D 3 49  ? 122.610 130.020 60.389  1.00 263.02 ? 52  ARG D C   1 
ATOM 4730 O O   . ARG D 3 49  ? 123.586 130.505 59.815  1.00 263.02 ? 52  ARG D O   1 
ATOM 4731 C CB  . ARG D 3 49  ? 122.292 132.269 61.469  1.00 263.02 ? 52  ARG D CB  1 
ATOM 4732 C CG  . ARG D 3 49  ? 121.314 133.274 62.050  1.00 263.02 ? 52  ARG D CG  1 
ATOM 4733 C CD  . ARG D 3 49  ? 121.910 134.671 62.067  1.00 263.02 ? 52  ARG D CD  1 
ATOM 4734 N NE  . ARG D 3 49  ? 120.960 135.665 62.550  1.00 263.02 ? 52  ARG D NE  1 
ATOM 4735 C CZ  . ARG D 3 49  ? 121.216 136.963 62.641  1.00 263.02 ? 52  ARG D CZ  1 
ATOM 4736 N NH1 . ARG D 3 49  ? 122.389 137.463 62.290  1.00 263.02 ? 52  ARG D NH1 1 
ATOM 4737 N NH2 . ARG D 3 49  ? 120.270 137.780 63.097  1.00 263.02 ? 52  ARG D NH2 1 
ATOM 4738 N N   . LYS D 3 50  ? 122.288 128.734 60.263  1.00 252.59 ? 53  LYS D N   1 
ATOM 4739 C CA  . LYS D 3 50  ? 123.074 127.857 59.404  1.00 252.59 ? 53  LYS D CA  1 
ATOM 4740 C C   . LYS D 3 50  ? 123.016 128.335 57.957  1.00 252.59 ? 53  LYS D C   1 
ATOM 4741 O O   . LYS D 3 50  ? 121.996 128.854 57.493  1.00 252.59 ? 53  LYS D O   1 
ATOM 4742 C CB  . LYS D 3 50  ? 122.576 126.412 59.504  1.00 252.59 ? 53  LYS D CB  1 
ATOM 4743 C CG  . LYS D 3 50  ? 121.271 126.131 58.775  1.00 252.59 ? 53  LYS D CG  1 
ATOM 4744 C CD  . LYS D 3 50  ? 121.130 124.651 58.455  1.00 252.59 ? 53  LYS D CD  1 
ATOM 4745 C CE  . LYS D 3 50  ? 119.873 124.376 57.645  1.00 252.59 ? 53  LYS D CE  1 
ATOM 4746 N NZ  . LYS D 3 50  ? 118.638 124.773 58.375  1.00 252.59 ? 53  LYS D NZ  1 
ATOM 4747 N N   . ASN D 3 51  ? 124.130 128.176 57.249  1.00 238.41 ? 54  ASN D N   1 
ATOM 4748 C CA  . ASN D 3 51  ? 124.250 128.596 55.862  1.00 238.41 ? 54  ASN D CA  1 
ATOM 4749 C C   . ASN D 3 51  ? 125.164 127.627 55.124  1.00 238.41 ? 54  ASN D C   1 
ATOM 4750 O O   . ASN D 3 51  ? 125.712 126.687 55.707  1.00 238.41 ? 54  ASN D O   1 
ATOM 4751 C CB  . ASN D 3 51  ? 124.785 130.033 55.761  1.00 238.41 ? 54  ASN D CB  1 
ATOM 4752 C CG  . ASN D 3 51  ? 124.447 130.692 54.437  1.00 238.41 ? 54  ASN D CG  1 
ATOM 4753 O OD1 . ASN D 3 51  ? 123.535 130.263 53.731  1.00 238.41 ? 54  ASN D OD1 1 
ATOM 4754 N ND2 . ASN D 3 51  ? 125.184 131.743 54.096  1.00 238.41 ? 54  ASN D ND2 1 
ATOM 4755 N N   . ASP D 3 52  ? 125.322 127.863 53.820  1.00 221.63 ? 55  ASP D N   1 
ATOM 4756 C CA  . ASP D 3 52  ? 126.195 127.023 53.009  1.00 221.63 ? 55  ASP D CA  1 
ATOM 4757 C C   . ASP D 3 52  ? 127.650 127.105 53.451  1.00 221.63 ? 55  ASP D C   1 
ATOM 4758 O O   . ASP D 3 52  ? 128.411 126.160 53.215  1.00 221.63 ? 55  ASP D O   1 
ATOM 4759 C CB  . ASP D 3 52  ? 126.077 127.412 51.534  1.00 221.63 ? 55  ASP D CB  1 
ATOM 4760 C CG  . ASP D 3 52  ? 124.665 127.264 51.004  1.00 221.63 ? 55  ASP D CG  1 
ATOM 4761 O OD1 . ASP D 3 52  ? 123.931 126.383 51.499  1.00 221.63 ? 55  ASP D OD1 1 
ATOM 4762 O OD2 . ASP D 3 52  ? 124.288 128.029 50.091  1.00 221.63 ? 55  ASP D OD2 1 
ATOM 4763 N N   . GLU D 3 53  ? 128.055 128.212 54.078  1.00 216.74 ? 56  GLU D N   1 
ATOM 4764 C CA  . GLU D 3 53  ? 129.429 128.335 54.555  1.00 216.74 ? 56  GLU D CA  1 
ATOM 4765 C C   . GLU D 3 53  ? 129.729 127.302 55.635  1.00 216.74 ? 56  GLU D C   1 
ATOM 4766 O O   . GLU D 3 53  ? 130.698 126.541 55.530  1.00 216.74 ? 56  GLU D O   1 
ATOM 4767 C CB  . GLU D 3 53  ? 129.674 129.750 55.079  1.00 216.74 ? 56  GLU D CB  1 
ATOM 4768 C CG  . GLU D 3 53  ? 129.346 130.849 54.080  1.00 216.74 ? 56  GLU D CG  1 
ATOM 4769 C CD  . GLU D 3 53  ? 129.481 132.237 54.674  1.00 216.74 ? 56  GLU D CD  1 
ATOM 4770 O OE1 . GLU D 3 53  ? 129.843 132.343 55.865  1.00 216.74 ? 56  GLU D OE1 1 
ATOM 4771 O OE2 . GLU D 3 53  ? 129.225 133.223 53.951  1.00 216.74 ? 56  GLU D OE2 1 
ATOM 4772 N N   . ASN D 3 54  ? 128.893 127.249 56.670  1.00 239.32 ? 57  ASN D N   1 
ATOM 4773 C CA  . ASN D 3 54  ? 129.041 126.317 57.783  1.00 239.32 ? 57  ASN D CA  1 
ATOM 4774 C C   . ASN D 3 54  ? 127.825 126.487 58.687  1.00 239.32 ? 57  ASN D C   1 
ATOM 4775 O O   . ASN D 3 54  ? 127.038 127.425 58.532  1.00 239.32 ? 57  ASN D O   1 
ATOM 4776 C CB  . ASN D 3 54  ? 130.336 126.547 58.568  1.00 239.32 ? 57  ASN D CB  1 
ATOM 4777 C CG  . ASN D 3 54  ? 130.756 125.330 59.370  1.00 239.32 ? 57  ASN D CG  1 
ATOM 4778 O OD1 . ASN D 3 54  ? 130.208 124.240 59.200  1.00 239.32 ? 57  ASN D OD1 1 
ATOM 4779 N ND2 . ASN D 3 54  ? 131.738 125.507 60.245  1.00 239.32 ? 57  ASN D ND2 1 
ATOM 4780 N N   . ILE D 3 55  ? 127.681 125.562 59.637  1.00 246.93 ? 58  ILE D N   1 
ATOM 4781 C CA  . ILE D 3 55  ? 126.578 125.627 60.588  1.00 246.93 ? 58  ILE D CA  1 
ATOM 4782 C C   . ILE D 3 55  ? 126.964 126.538 61.745  1.00 246.93 ? 58  ILE D C   1 
ATOM 4783 O O   . ILE D 3 55  ? 128.019 126.363 62.369  1.00 246.93 ? 58  ILE D O   1 
ATOM 4784 C CB  . ILE D 3 55  ? 126.212 124.220 61.085  1.00 246.93 ? 58  ILE D CB  1 
ATOM 4785 C CG1 . ILE D 3 55  ? 126.039 123.263 59.903  1.00 246.93 ? 58  ILE D CG1 1 
ATOM 4786 C CG2 . ILE D 3 55  ? 124.946 124.265 61.927  1.00 246.93 ? 58  ILE D CG2 1 
ATOM 4787 C CD1 . ILE D 3 55  ? 124.937 123.659 58.946  1.00 246.93 ? 58  ILE D CD1 1 
ATOM 4788 N N   . THR D 3 56  ? 126.111 127.518 62.038  1.00 249.00 ? 59  THR D N   1 
ATOM 4789 C CA  . THR D 3 56  ? 126.373 128.499 63.082  1.00 249.00 ? 59  THR D CA  1 
ATOM 4790 C C   . THR D 3 56  ? 125.202 128.556 64.052  1.00 249.00 ? 59  THR D C   1 
ATOM 4791 O O   . THR D 3 56  ? 124.043 128.404 63.652  1.00 249.00 ? 59  THR D O   1 
ATOM 4792 C CB  . THR D 3 56  ? 126.623 129.895 62.493  1.00 249.00 ? 59  THR D CB  1 
ATOM 4793 O OG1 . THR D 3 56  ? 125.489 130.299 61.716  1.00 249.00 ? 59  THR D OG1 1 
ATOM 4794 C CG2 . THR D 3 56  ? 127.864 129.891 61.610  1.00 249.00 ? 59  THR D CG2 1 
ATOM 4795 N N   . LEU D 3 57  ? 125.513 128.778 65.327  1.00 241.39 ? 60  LEU D N   1 
ATOM 4796 C CA  . LEU D 3 57  ? 124.498 128.906 66.365  1.00 241.39 ? 60  LEU D CA  1 
ATOM 4797 C C   . LEU D 3 57  ? 125.072 129.743 67.499  1.00 241.39 ? 60  LEU D C   1 
ATOM 4798 O O   . LEU D 3 57  ? 126.290 129.864 67.648  1.00 241.39 ? 60  LEU D O   1 
ATOM 4799 C CB  . LEU D 3 57  ? 124.033 127.539 66.883  1.00 241.39 ? 60  LEU D CB  1 
ATOM 4800 C CG  . LEU D 3 57  ? 124.931 126.787 67.872  1.00 241.39 ? 60  LEU D CG  1 
ATOM 4801 C CD1 . LEU D 3 57  ? 124.166 125.634 68.505  1.00 241.39 ? 60  LEU D CD1 1 
ATOM 4802 C CD2 . LEU D 3 57  ? 126.203 126.277 67.210  1.00 241.39 ? 60  LEU D CD2 1 
ATOM 4803 N N   . GLU D 3 58  ? 124.176 130.320 68.299  1.00 235.61 ? 61  GLU D N   1 
ATOM 4804 C CA  . GLU D 3 58  ? 124.600 131.166 69.407  1.00 235.61 ? 61  GLU D CA  1 
ATOM 4805 C C   . GLU D 3 58  ? 123.523 131.177 70.483  1.00 235.61 ? 61  GLU D C   1 
ATOM 4806 O O   . GLU D 3 58  ? 122.332 131.043 70.198  1.00 235.61 ? 61  GLU D O   1 
ATOM 4807 C CB  . GLU D 3 58  ? 124.906 132.593 68.928  1.00 235.61 ? 61  GLU D CB  1 
ATOM 4808 C CG  . GLU D 3 58  ? 125.555 133.489 69.971  1.00 235.61 ? 61  GLU D CG  1 
ATOM 4809 C CD  . GLU D 3 58  ? 125.868 134.872 69.435  1.00 235.61 ? 61  GLU D CD  1 
ATOM 4810 O OE1 . GLU D 3 58  ? 125.596 135.125 68.243  1.00 235.61 ? 61  GLU D OE1 1 
ATOM 4811 O OE2 . GLU D 3 58  ? 126.387 135.707 70.206  1.00 235.61 ? 61  GLU D OE2 1 
ATOM 4812 N N   . THR D 3 59  ? 123.962 131.325 71.734  1.00 234.31 ? 62  THR D N   1 
ATOM 4813 C CA  . THR D 3 59  ? 123.070 131.452 72.881  1.00 234.31 ? 62  THR D CA  1 
ATOM 4814 C C   . THR D 3 59  ? 123.603 132.551 73.787  1.00 234.31 ? 62  THR D C   1 
ATOM 4815 O O   . THR D 3 59  ? 124.756 132.484 74.223  1.00 234.31 ? 62  THR D O   1 
ATOM 4816 C CB  . THR D 3 59  ? 122.961 130.137 73.665  1.00 234.31 ? 62  THR D CB  1 
ATOM 4817 O OG1 . THR D 3 59  ? 124.270 129.701 74.056  1.00 234.31 ? 62  THR D OG1 1 
ATOM 4818 C CG2 . THR D 3 59  ? 122.299 129.053 72.824  1.00 234.31 ? 62  THR D CG2 1 
ATOM 4819 N N   . VAL D 3 60  ? 122.773 133.556 74.073  1.00 214.27 ? 63  VAL D N   1 
ATOM 4820 C CA  . VAL D 3 60  ? 123.194 134.725 74.843  1.00 214.27 ? 63  VAL D CA  1 
ATOM 4821 C C   . VAL D 3 60  ? 122.047 135.187 75.736  1.00 214.27 ? 63  VAL D C   1 
ATOM 4822 O O   . VAL D 3 60  ? 120.966 134.597 75.757  1.00 214.27 ? 63  VAL D O   1 
ATOM 4823 C CB  . VAL D 3 60  ? 123.662 135.888 73.935  1.00 214.27 ? 63  VAL D CB  1 
ATOM 4824 C CG1 . VAL D 3 60  ? 125.011 135.576 73.303  1.00 214.27 ? 63  VAL D CG1 1 
ATOM 4825 C CG2 . VAL D 3 60  ? 122.626 136.175 72.863  1.00 214.27 ? 63  VAL D CG2 1 
ATOM 4826 N N   . CYS D 3 61  ? 122.307 136.241 76.511  1.00 195.07 ? 64  CYS D N   1 
ATOM 4827 C CA  . CYS D 3 61  ? 121.273 136.949 77.256  1.00 195.07 ? 64  CYS D CA  1 
ATOM 4828 C C   . CYS D 3 61  ? 120.741 138.096 76.407  1.00 195.07 ? 64  CYS D C   1 
ATOM 4829 O O   . CYS D 3 61  ? 121.485 138.698 75.627  1.00 195.07 ? 64  CYS D O   1 
ATOM 4830 C CB  . CYS D 3 61  ? 121.823 137.507 78.572  1.00 195.07 ? 64  CYS D CB  1 
ATOM 4831 S SG  . CYS D 3 61  ? 122.415 136.307 79.793  1.00 195.07 ? 64  CYS D SG  1 
ATOM 4832 N N   . HIS D 3 62  ? 119.454 138.402 76.561  1.00 229.45 ? 65  HIS D N   1 
ATOM 4833 C CA  . HIS D 3 62  ? 118.882 139.546 75.863  1.00 229.45 ? 65  HIS D CA  1 
ATOM 4834 C C   . HIS D 3 62  ? 117.607 139.991 76.560  1.00 229.45 ? 65  HIS D C   1 
ATOM 4835 O O   . HIS D 3 62  ? 116.914 139.179 77.177  1.00 229.45 ? 65  HIS D O   1 
ATOM 4836 C CB  . HIS D 3 62  ? 118.587 139.222 74.394  1.00 229.45 ? 65  HIS D CB  1 
ATOM 4837 C CG  . HIS D 3 62  ? 118.539 140.426 73.508  1.00 229.45 ? 65  HIS D CG  1 
ATOM 4838 N ND1 . HIS D 3 62  ? 117.425 141.230 73.402  1.00 229.45 ? 65  HIS D ND1 1 
ATOM 4839 C CD2 . HIS D 3 62  ? 119.471 140.965 72.686  1.00 229.45 ? 65  HIS D CD2 1 
ATOM 4840 C CE1 . HIS D 3 62  ? 117.672 142.212 72.554  1.00 229.45 ? 65  HIS D CE1 1 
ATOM 4841 N NE2 . HIS D 3 62  ? 118.906 142.074 72.105  1.00 229.45 ? 65  HIS D NE2 1 
ATOM 4842 N N   . ASP D 3 63  ? 117.306 141.280 76.459  1.00 219.54 ? 66  ASP D N   1 
ATOM 4843 C CA  . ASP D 3 63  ? 116.059 141.794 77.005  1.00 219.54 ? 66  ASP D CA  1 
ATOM 4844 C C   . ASP D 3 63  ? 114.888 141.283 76.171  1.00 219.54 ? 66  ASP D C   1 
ATOM 4845 O O   . ASP D 3 63  ? 114.950 141.327 74.934  1.00 219.54 ? 66  ASP D O   1 
ATOM 4846 C CB  . ASP D 3 63  ? 116.065 143.322 77.026  1.00 219.54 ? 66  ASP D CB  1 
ATOM 4847 C CG  . ASP D 3 63  ? 114.921 143.898 77.839  1.00 219.54 ? 66  ASP D CG  1 
ATOM 4848 O OD1 . ASP D 3 63  ? 115.061 143.994 79.077  1.00 219.54 ? 66  ASP D OD1 1 
ATOM 4849 O OD2 . ASP D 3 63  ? 113.880 144.247 77.244  1.00 219.54 ? 66  ASP D OD2 1 
ATOM 4850 N N   . PRO D 3 64  ? 113.818 140.784 76.796  1.00 227.72 ? 67  PRO D N   1 
ATOM 4851 C CA  . PRO D 3 64  ? 112.687 140.270 76.004  1.00 227.72 ? 67  PRO D CA  1 
ATOM 4852 C C   . PRO D 3 64  ? 112.039 141.318 75.116  1.00 227.72 ? 67  PRO D C   1 
ATOM 4853 O O   . PRO D 3 64  ? 111.577 140.991 74.015  1.00 227.72 ? 67  PRO D O   1 
ATOM 4854 C CB  . PRO D 3 64  ? 111.719 139.751 77.078  1.00 227.72 ? 67  PRO D CB  1 
ATOM 4855 C CG  . PRO D 3 64  ? 112.075 140.517 78.311  1.00 227.72 ? 67  PRO D CG  1 
ATOM 4856 C CD  . PRO D 3 64  ? 113.559 140.715 78.244  1.00 227.72 ? 67  PRO D CD  1 
ATOM 4857 N N   . LYS D 3 65  ? 111.991 142.575 75.562  1.00 242.04 ? 68  LYS D N   1 
ATOM 4858 C CA  . LYS D 3 65  ? 111.347 143.623 74.780  1.00 242.04 ? 68  LYS D CA  1 
ATOM 4859 C C   . LYS D 3 65  ? 112.281 144.268 73.765  1.00 242.04 ? 68  LYS D C   1 
ATOM 4860 O O   . LYS D 3 65  ? 111.802 144.930 72.838  1.00 242.04 ? 68  LYS D O   1 
ATOM 4861 C CB  . LYS D 3 65  ? 110.778 144.696 75.711  1.00 242.04 ? 68  LYS D CB  1 
ATOM 4862 C CG  . LYS D 3 65  ? 109.776 144.166 76.724  1.00 242.04 ? 68  LYS D CG  1 
ATOM 4863 C CD  . LYS D 3 65  ? 109.198 145.288 77.570  1.00 242.04 ? 68  LYS D CD  1 
ATOM 4864 C CE  . LYS D 3 65  ? 108.436 146.287 76.716  1.00 242.04 ? 68  LYS D CE  1 
ATOM 4865 N NZ  . LYS D 3 65  ? 107.847 147.381 77.535  1.00 242.04 ? 68  LYS D NZ  1 
ATOM 4866 N N   . LEU D 3 66  ? 113.604 144.090 73.915  1.00 231.69 ? 69  LEU D N   1 
ATOM 4867 C CA  . LEU D 3 66  ? 114.510 144.680 72.942  1.00 231.69 ? 69  LEU D CA  1 
ATOM 4868 C C   . LEU D 3 66  ? 114.736 143.729 71.770  1.00 231.69 ? 69  LEU D C   1 
ATOM 4869 O O   . LEU D 3 66  ? 114.699 142.506 71.937  1.00 231.69 ? 69  LEU D O   1 
ATOM 4870 C CB  . LEU D 3 66  ? 115.851 145.017 73.593  1.00 231.69 ? 69  LEU D CB  1 
ATOM 4871 C CG  . LEU D 3 66  ? 116.018 146.402 74.229  1.00 231.69 ? 69  LEU D CG  1 
ATOM 4872 C CD1 . LEU D 3 66  ? 115.816 147.500 73.195  1.00 231.69 ? 69  LEU D CD1 1 
ATOM 4873 C CD2 . LEU D 3 66  ? 115.080 146.597 75.411  1.00 231.69 ? 69  LEU D CD2 1 
ATOM 4874 N N   . PRO D 3 67  ? 114.962 144.264 70.574  1.00 233.02 ? 70  PRO D N   1 
ATOM 4875 C CA  . PRO D 3 67  ? 115.211 143.406 69.414  1.00 233.02 ? 70  PRO D CA  1 
ATOM 4876 C C   . PRO D 3 67  ? 116.670 142.987 69.311  1.00 233.02 ? 70  PRO D C   1 
ATOM 4877 O O   . PRO D 3 67  ? 117.576 143.628 69.848  1.00 233.02 ? 70  PRO D O   1 
ATOM 4878 C CB  . PRO D 3 67  ? 114.816 144.297 68.232  1.00 233.02 ? 70  PRO D CB  1 
ATOM 4879 C CG  . PRO D 3 67  ? 115.125 145.675 68.710  1.00 233.02 ? 70  PRO D CG  1 
ATOM 4880 C CD  . PRO D 3 67  ? 114.834 145.682 70.193  1.00 233.02 ? 70  PRO D CD  1 
ATOM 4881 N N   . TYR D 3 68  ? 116.882 141.887 68.595  1.00 252.19 ? 71  TYR D N   1 
ATOM 4882 C CA  . TYR D 3 68  ? 118.213 141.378 68.292  1.00 252.19 ? 71  TYR D CA  1 
ATOM 4883 C C   . TYR D 3 68  ? 118.470 141.524 66.799  1.00 252.19 ? 71  TYR D C   1 
ATOM 4884 O O   . TYR D 3 68  ? 117.729 140.966 65.982  1.00 252.19 ? 71  TYR D O   1 
ATOM 4885 C CB  . TYR D 3 68  ? 118.354 139.914 68.716  1.00 252.19 ? 71  TYR D CB  1 
ATOM 4886 C CG  . TYR D 3 68  ? 119.571 139.221 68.142  1.00 252.19 ? 71  TYR D CG  1 
ATOM 4887 C CD1 . TYR D 3 68  ? 120.835 139.440 68.673  1.00 252.19 ? 71  TYR D CD1 1 
ATOM 4888 C CD2 . TYR D 3 68  ? 119.454 138.341 67.073  1.00 252.19 ? 71  TYR D CD2 1 
ATOM 4889 C CE1 . TYR D 3 68  ? 121.950 138.808 68.152  1.00 252.19 ? 71  TYR D CE1 1 
ATOM 4890 C CE2 . TYR D 3 68  ? 120.562 137.704 66.545  1.00 252.19 ? 71  TYR D CE2 1 
ATOM 4891 C CZ  . TYR D 3 68  ? 121.807 137.941 67.089  1.00 252.19 ? 71  TYR D CZ  1 
ATOM 4892 O OH  . TYR D 3 68  ? 122.913 137.308 66.568  1.00 252.19 ? 71  TYR D OH  1 
ATOM 4893 N N   . HIS D 3 69  ? 119.525 142.265 66.452  1.00 253.14 ? 72  HIS D N   1 
ATOM 4894 C CA  . HIS D 3 69  ? 119.862 142.556 65.057  1.00 253.14 ? 72  HIS D CA  1 
ATOM 4895 C C   . HIS D 3 69  ? 118.668 143.151 64.313  1.00 253.14 ? 72  HIS D C   1 
ATOM 4896 O O   . HIS D 3 69  ? 118.374 142.775 63.176  1.00 253.14 ? 72  HIS D O   1 
ATOM 4897 C CB  . HIS D 3 69  ? 120.385 141.307 64.340  1.00 253.14 ? 72  HIS D CB  1 
ATOM 4898 C CG  . HIS D 3 69  ? 121.108 141.602 63.062  1.00 253.14 ? 72  HIS D CG  1 
ATOM 4899 N ND1 . HIS D 3 69  ? 122.240 142.386 63.012  1.00 253.14 ? 72  HIS D ND1 1 
ATOM 4900 C CD2 . HIS D 3 69  ? 120.859 141.218 61.788  1.00 253.14 ? 72  HIS D CD2 1 
ATOM 4901 C CE1 . HIS D 3 69  ? 122.657 142.473 61.761  1.00 253.14 ? 72  HIS D CE1 1 
ATOM 4902 N NE2 . HIS D 3 69  ? 121.837 141.773 60.999  1.00 253.14 ? 72  HIS D NE2 1 
ATOM 4903 N N   . ASP D 3 70  ? 117.968 144.079 64.968  1.00 257.53 ? 73  ASP D N   1 
ATOM 4904 C CA  . ASP D 3 70  ? 116.787 144.761 64.444  1.00 257.53 ? 73  ASP D CA  1 
ATOM 4905 C C   . ASP D 3 70  ? 115.628 143.812 64.167  1.00 257.53 ? 73  ASP D C   1 
ATOM 4906 O O   . ASP D 3 70  ? 114.765 144.119 63.338  1.00 257.53 ? 73  ASP D O   1 
ATOM 4907 C CB  . ASP D 3 70  ? 117.110 145.562 63.177  1.00 257.53 ? 73  ASP D CB  1 
ATOM 4908 C CG  . ASP D 3 70  ? 118.172 146.618 63.410  1.00 257.53 ? 73  ASP D CG  1 
ATOM 4909 O OD1 . ASP D 3 70  ? 118.665 146.725 64.552  1.00 257.53 ? 73  ASP D OD1 1 
ATOM 4910 O OD2 . ASP D 3 70  ? 118.513 147.343 62.451  1.00 257.53 ? 73  ASP D OD2 1 
ATOM 4911 N N   . PHE D 3 71  ? 115.581 142.663 64.837  1.00 260.55 ? 74  PHE D N   1 
ATOM 4912 C CA  . PHE D 3 71  ? 114.476 141.719 64.720  1.00 260.55 ? 74  PHE D CA  1 
ATOM 4913 C C   . PHE D 3 71  ? 113.805 141.573 66.080  1.00 260.55 ? 74  PHE D C   1 
ATOM 4914 O O   . PHE D 3 71  ? 114.470 141.259 67.073  1.00 260.55 ? 74  PHE D O   1 
ATOM 4915 C CB  . PHE D 3 71  ? 114.959 140.362 64.208  1.00 260.55 ? 74  PHE D CB  1 
ATOM 4916 C CG  . PHE D 3 71  ? 115.147 140.307 62.718  1.00 260.55 ? 74  PHE D CG  1 
ATOM 4917 C CD1 . PHE D 3 71  ? 116.368 140.622 62.146  1.00 260.55 ? 74  PHE D CD1 1 
ATOM 4918 C CD2 . PHE D 3 71  ? 114.100 139.939 61.889  1.00 260.55 ? 74  PHE D CD2 1 
ATOM 4919 C CE1 . PHE D 3 71  ? 116.542 140.572 60.775  1.00 260.55 ? 74  PHE D CE1 1 
ATOM 4920 C CE2 . PHE D 3 71  ? 114.267 139.886 60.518  1.00 260.55 ? 74  PHE D CE2 1 
ATOM 4921 C CZ  . PHE D 3 71  ? 115.489 140.203 59.960  1.00 260.55 ? 74  PHE D CZ  1 
ATOM 4922 N N   . ILE D 3 72  ? 112.494 141.791 66.118  1.00 248.54 ? 75  ILE D N   1 
ATOM 4923 C CA  . ILE D 3 72  ? 111.737 141.735 67.363  1.00 248.54 ? 75  ILE D CA  1 
ATOM 4924 C C   . ILE D 3 72  ? 111.508 140.283 67.759  1.00 248.54 ? 75  ILE D C   1 
ATOM 4925 O O   . ILE D 3 72  ? 111.061 139.462 66.949  1.00 248.54 ? 75  ILE D O   1 
ATOM 4926 C CB  . ILE D 3 72  ? 110.403 142.489 67.216  1.00 248.54 ? 75  ILE D CB  1 
ATOM 4927 C CG1 . ILE D 3 72  ? 110.651 143.984 67.004  1.00 248.54 ? 75  ILE D CG1 1 
ATOM 4928 C CG2 . ILE D 3 72  ? 109.519 142.259 68.433  1.00 248.54 ? 75  ILE D CG2 1 
ATOM 4929 C CD1 . ILE D 3 72  ? 111.213 144.689 68.220  1.00 248.54 ? 75  ILE D CD1 1 
ATOM 4930 N N   . LEU D 3 73  ? 111.815 139.961 69.015  1.00 241.75 ? 76  LEU D N   1 
ATOM 4931 C CA  . LEU D 3 73  ? 111.559 138.636 69.579  1.00 241.75 ? 76  LEU D CA  1 
ATOM 4932 C C   . LEU D 3 73  ? 110.166 138.673 70.202  1.00 241.75 ? 76  LEU D C   1 
ATOM 4933 O O   . LEU D 3 73  ? 110.003 138.938 71.393  1.00 241.75 ? 76  LEU D O   1 
ATOM 4934 C CB  . LEU D 3 73  ? 112.627 138.250 70.598  1.00 241.75 ? 76  LEU D CB  1 
ATOM 4935 C CG  . LEU D 3 73  ? 114.053 137.989 70.098  1.00 241.75 ? 76  LEU D CG  1 
ATOM 4936 C CD1 . LEU D 3 73  ? 114.039 137.167 68.816  1.00 241.75 ? 76  LEU D CD1 1 
ATOM 4937 C CD2 . LEU D 3 73  ? 114.839 139.283 69.914  1.00 241.75 ? 76  LEU D CD2 1 
ATOM 4938 N N   . GLU D 3 74  ? 109.152 138.405 69.375  1.00 237.34 ? 77  GLU D N   1 
ATOM 4939 C CA  . GLU D 3 74  ? 107.771 138.490 69.840  1.00 237.34 ? 77  GLU D CA  1 
ATOM 4940 C C   . GLU D 3 74  ? 107.454 137.407 70.865  1.00 237.34 ? 77  GLU D C   1 
ATOM 4941 O O   . GLU D 3 74  ? 106.706 137.649 71.819  1.00 237.34 ? 77  GLU D O   1 
ATOM 4942 C CB  . GLU D 3 74  ? 106.813 138.408 68.651  1.00 237.34 ? 77  GLU D CB  1 
ATOM 4943 C CG  . GLU D 3 74  ? 107.044 137.211 67.742  1.00 237.34 ? 77  GLU D CG  1 
ATOM 4944 C CD  . GLU D 3 74  ? 106.097 137.186 66.558  1.00 237.34 ? 77  GLU D CD  1 
ATOM 4945 O OE1 . GLU D 3 74  ? 105.282 138.124 66.427  1.00 237.34 ? 77  GLU D OE1 1 
ATOM 4946 O OE2 . GLU D 3 74  ? 106.168 136.229 65.759  1.00 237.34 ? 77  GLU D OE2 1 
ATOM 4947 N N   . ASP D 3 75  ? 108.011 136.206 70.688  1.00 248.38 ? 78  ASP D N   1 
ATOM 4948 C CA  . ASP D 3 75  ? 107.735 135.078 71.570  1.00 248.38 ? 78  ASP D CA  1 
ATOM 4949 C C   . ASP D 3 75  ? 108.749 134.953 72.701  1.00 248.38 ? 78  ASP D C   1 
ATOM 4950 O O   . ASP D 3 75  ? 108.994 133.841 73.189  1.00 248.38 ? 78  ASP D O   1 
ATOM 4951 C CB  . ASP D 3 75  ? 107.678 133.782 70.760  1.00 248.38 ? 78  ASP D CB  1 
ATOM 4952 C CG  . ASP D 3 75  ? 106.581 133.797 69.715  1.00 248.38 ? 78  ASP D CG  1 
ATOM 4953 O OD1 . ASP D 3 75  ? 105.555 134.473 69.938  1.00 248.38 ? 78  ASP D OD1 1 
ATOM 4954 O OD2 . ASP D 3 75  ? 106.744 133.133 68.670  1.00 248.38 ? 78  ASP D OD2 1 
ATOM 4955 N N   . ALA D 3 76  ? 109.348 136.065 73.132  1.00 243.30 ? 79  ALA D N   1 
ATOM 4956 C CA  . ALA D 3 76  ? 110.313 136.016 74.223  1.00 243.30 ? 79  ALA D CA  1 
ATOM 4957 C C   . ALA D 3 76  ? 109.660 135.708 75.563  1.00 243.30 ? 79  ALA D C   1 
ATOM 4958 O O   . ALA D 3 76  ? 110.349 135.263 76.488  1.00 243.30 ? 79  ALA D O   1 
ATOM 4959 C CB  . ALA D 3 76  ? 111.077 137.338 74.307  1.00 243.30 ? 79  ALA D CB  1 
ATOM 4960 N N   . ALA D 3 77  ? 108.350 135.932 75.690  1.00 246.54 ? 80  ALA D N   1 
ATOM 4961 C CA  . ALA D 3 77  ? 107.667 135.689 76.955  1.00 246.54 ? 80  ALA D CA  1 
ATOM 4962 C C   . ALA D 3 77  ? 107.515 134.205 77.263  1.00 246.54 ? 80  ALA D C   1 
ATOM 4963 O O   . ALA D 3 77  ? 107.174 133.855 78.399  1.00 246.54 ? 80  ALA D O   1 
ATOM 4964 C CB  . ALA D 3 77  ? 106.293 136.360 76.949  1.00 246.54 ? 80  ALA D CB  1 
ATOM 4965 N N   . SER D 3 78  ? 107.750 133.331 76.287  1.00 229.01 ? 81  SER D N   1 
ATOM 4966 C CA  . SER D 3 78  ? 107.604 131.903 76.515  1.00 229.01 ? 81  SER D CA  1 
ATOM 4967 C C   . SER D 3 78  ? 108.662 131.411 77.502  1.00 229.01 ? 81  SER D C   1 
ATOM 4968 O O   . SER D 3 78  ? 109.822 131.831 77.446  1.00 229.01 ? 81  SER D O   1 
ATOM 4969 C CB  . SER D 3 78  ? 107.720 131.137 75.199  1.00 229.01 ? 81  SER D CB  1 
ATOM 4970 O OG  . SER D 3 78  ? 108.977 131.363 74.586  1.00 229.01 ? 81  SER D OG  1 
ATOM 4971 N N   . PRO D 3 79  ? 108.288 130.515 78.421  1.00 200.85 ? 82  PRO D N   1 
ATOM 4972 C CA  . PRO D 3 79  ? 109.264 129.998 79.390  1.00 200.85 ? 82  PRO D CA  1 
ATOM 4973 C C   . PRO D 3 79  ? 110.197 128.938 78.829  1.00 200.85 ? 82  PRO D C   1 
ATOM 4974 O O   . PRO D 3 79  ? 111.158 128.563 79.514  1.00 200.85 ? 82  PRO D O   1 
ATOM 4975 C CB  . PRO D 3 79  ? 108.373 129.411 80.492  1.00 200.85 ? 82  PRO D CB  1 
ATOM 4976 C CG  . PRO D 3 79  ? 107.141 128.984 79.768  1.00 200.85 ? 82  PRO D CG  1 
ATOM 4977 C CD  . PRO D 3 79  ? 106.932 129.992 78.665  1.00 200.85 ? 82  PRO D CD  1 
ATOM 4978 N N   . LYS D 3 80  ? 109.952 128.447 77.616  1.00 222.67 ? 83  LYS D N   1 
ATOM 4979 C CA  . LYS D 3 80  ? 110.781 127.421 77.004  1.00 222.67 ? 83  LYS D CA  1 
ATOM 4980 C C   . LYS D 3 80  ? 111.277 127.909 75.650  1.00 222.67 ? 83  LYS D C   1 
ATOM 4981 O O   . LYS D 3 80  ? 110.605 128.677 74.958  1.00 222.67 ? 83  LYS D O   1 
ATOM 4982 C CB  . LYS D 3 80  ? 110.016 126.099 76.842  1.00 222.67 ? 83  LYS D CB  1 
ATOM 4983 C CG  . LYS D 3 80  ? 109.543 125.491 78.153  1.00 222.67 ? 83  LYS D CG  1 
ATOM 4984 C CD  . LYS D 3 80  ? 108.805 124.182 77.922  1.00 222.67 ? 83  LYS D CD  1 
ATOM 4985 C CE  . LYS D 3 80  ? 108.349 123.567 79.235  1.00 222.67 ? 83  LYS D CE  1 
ATOM 4986 N NZ  . LYS D 3 80  ? 107.626 122.282 79.026  1.00 222.67 ? 83  LYS D NZ  1 
ATOM 4987 N N   . CYS D 3 81  ? 112.469 127.448 75.280  1.00 238.96 ? 84  CYS D N   1 
ATOM 4988 C CA  . CYS D 3 81  ? 113.108 127.850 74.031  1.00 238.96 ? 84  CYS D CA  1 
ATOM 4989 C C   . CYS D 3 81  ? 112.620 126.933 72.915  1.00 238.96 ? 84  CYS D C   1 
ATOM 4990 O O   . CYS D 3 81  ? 113.076 125.792 72.794  1.00 238.96 ? 84  CYS D O   1 
ATOM 4991 C CB  . CYS D 3 81  ? 114.628 127.797 74.163  1.00 238.96 ? 84  CYS D CB  1 
ATOM 4992 S SG  . CYS D 3 81  ? 115.486 129.235 73.481  1.00 238.96 ? 84  CYS D SG  1 
ATOM 4993 N N   . ILE D 3 82  ? 111.698 127.434 72.097  1.00 253.51 ? 85  ILE D N   1 
ATOM 4994 C CA  . ILE D 3 82  ? 111.137 126.688 70.977  1.00 253.51 ? 85  ILE D CA  1 
ATOM 4995 C C   . ILE D 3 82  ? 111.597 127.360 69.692  1.00 253.51 ? 85  ILE D C   1 
ATOM 4996 O O   . ILE D 3 82  ? 111.308 128.541 69.463  1.00 253.51 ? 85  ILE D O   1 
ATOM 4997 C CB  . ILE D 3 82  ? 109.604 126.622 71.048  1.00 253.51 ? 85  ILE D CB  1 
ATOM 4998 C CG1 . ILE D 3 82  ? 109.157 126.109 72.418  1.00 253.51 ? 85  ILE D CG1 1 
ATOM 4999 C CG2 . ILE D 3 82  ? 109.057 125.738 69.938  1.00 253.51 ? 85  ILE D CG2 1 
ATOM 5000 C CD1 . ILE D 3 82  ? 109.730 124.757 72.780  1.00 253.51 ? 85  ILE D CD1 1 
ATOM 5001 N N   . MET D 3 83  ? 112.304 126.607 68.852  1.00 249.09 ? 86  MET D N   1 
ATOM 5002 C CA  . MET D 3 83  ? 112.888 127.157 67.632  1.00 249.09 ? 86  MET D CA  1 
ATOM 5003 C C   . MET D 3 83  ? 111.779 127.551 66.665  1.00 249.09 ? 86  MET D C   1 
ATOM 5004 O O   . MET D 3 83  ? 111.027 126.696 66.187  1.00 249.09 ? 86  MET D O   1 
ATOM 5005 C CB  . MET D 3 83  ? 113.829 126.140 66.994  1.00 249.09 ? 86  MET D CB  1 
ATOM 5006 C CG  . MET D 3 83  ? 114.926 125.650 67.920  1.00 249.09 ? 86  MET D CG  1 
ATOM 5007 S SD  . MET D 3 83  ? 115.982 126.982 68.521  1.00 249.09 ? 86  MET D SD  1 
ATOM 5008 C CE  . MET D 3 83  ? 116.719 127.550 66.992  1.00 249.09 ? 86  MET D CE  1 
ATOM 5009 N N   . LYS D 3 84  ? 111.675 128.845 66.377  1.00 270.67 ? 87  LYS D N   1 
ATOM 5010 C CA  . LYS D 3 84  ? 110.702 129.362 65.427  1.00 270.67 ? 87  LYS D CA  1 
ATOM 5011 C C   . LYS D 3 84  ? 111.426 130.021 64.262  1.00 270.67 ? 87  LYS D C   1 
ATOM 5012 O O   . LYS D 3 84  ? 112.419 130.731 64.456  1.00 270.67 ? 87  LYS D O   1 
ATOM 5013 C CB  . LYS D 3 84  ? 109.752 130.359 66.097  1.00 270.67 ? 87  LYS D CB  1 
ATOM 5014 C CG  . LYS D 3 84  ? 108.627 130.840 65.195  1.00 270.67 ? 87  LYS D CG  1 
ATOM 5015 C CD  . LYS D 3 84  ? 107.449 131.351 66.006  1.00 270.67 ? 87  LYS D CD  1 
ATOM 5016 C CE  . LYS D 3 84  ? 106.838 130.239 66.844  1.00 270.67 ? 87  LYS D CE  1 
ATOM 5017 N NZ  . LYS D 3 84  ? 105.653 130.705 67.616  1.00 270.67 ? 87  LYS D NZ  1 
ATOM 5018 N N   . GLU D 3 85  ? 110.927 129.771 63.054  1.00 264.37 ? 88  GLU D N   1 
ATOM 5019 C CA  . GLU D 3 85  ? 111.571 130.267 61.848  1.00 264.37 ? 88  GLU D CA  1 
ATOM 5020 C C   . GLU D 3 85  ? 111.296 131.755 61.651  1.00 264.37 ? 88  GLU D C   1 
ATOM 5021 O O   . GLU D 3 85  ? 110.194 132.250 61.903  1.00 264.37 ? 88  GLU D O   1 
ATOM 5022 C CB  . GLU D 3 85  ? 111.092 129.479 60.628  1.00 264.37 ? 88  GLU D CB  1 
ATOM 5023 C CG  . GLU D 3 85  ? 111.819 129.821 59.337  1.00 264.37 ? 88  GLU D CG  1 
ATOM 5024 C CD  . GLU D 3 85  ? 111.346 128.987 58.163  1.00 264.37 ? 88  GLU D CD  1 
ATOM 5025 O OE1 . GLU D 3 85  ? 110.441 128.149 58.353  1.00 264.37 ? 88  GLU D OE1 1 
ATOM 5026 O OE2 . GLU D 3 85  ? 111.882 129.171 57.049  1.00 264.37 ? 88  GLU D OE2 1 
ATOM 5027 N N   . LYS D 3 86  ? 112.324 132.467 61.193  1.00 251.83 ? 89  LYS D N   1 
ATOM 5028 C CA  . LYS D 3 86  ? 112.262 133.891 60.904  1.00 251.83 ? 89  LYS D CA  1 
ATOM 5029 C C   . LYS D 3 86  ? 113.008 134.145 59.602  1.00 251.83 ? 89  LYS D C   1 
ATOM 5030 O O   . LYS D 3 86  ? 114.126 133.646 59.413  1.00 251.83 ? 89  LYS D O   1 
ATOM 5031 C CB  . LYS D 3 86  ? 112.870 134.715 62.045  1.00 251.83 ? 89  LYS D CB  1 
ATOM 5032 C CG  . LYS D 3 86  ? 112.600 136.208 61.961  1.00 251.83 ? 89  LYS D CG  1 
ATOM 5033 C CD  . LYS D 3 86  ? 111.119 136.509 62.126  1.00 251.83 ? 89  LYS D CD  1 
ATOM 5034 C CE  . LYS D 3 86  ? 110.871 138.002 62.257  1.00 251.83 ? 89  LYS D CE  1 
ATOM 5035 N NZ  . LYS D 3 86  ? 111.542 138.572 63.458  1.00 251.83 ? 89  LYS D NZ  1 
ATOM 5036 N N   . LYS D 3 87  ? 112.388 134.916 58.712  1.00 237.41 ? 90  LYS D N   1 
ATOM 5037 C CA  . LYS D 3 87  ? 112.966 135.179 57.402  1.00 237.41 ? 90  LYS D CA  1 
ATOM 5038 C C   . LYS D 3 87  ? 114.071 136.223 57.503  1.00 237.41 ? 90  LYS D C   1 
ATOM 5039 O O   . LYS D 3 87  ? 113.941 137.215 58.228  1.00 237.41 ? 90  LYS D O   1 
ATOM 5040 C CB  . LYS D 3 87  ? 111.881 135.647 56.433  1.00 237.41 ? 90  LYS D CB  1 
ATOM 5041 C CG  . LYS D 3 87  ? 112.382 135.980 55.036  1.00 237.41 ? 90  LYS D CG  1 
ATOM 5042 C CD  . LYS D 3 87  ? 113.021 134.771 54.372  1.00 237.41 ? 90  LYS D CD  1 
ATOM 5043 C CE  . LYS D 3 87  ? 113.497 135.100 52.966  1.00 237.41 ? 90  LYS D CE  1 
ATOM 5044 N NZ  . LYS D 3 87  ? 114.490 136.210 52.960  1.00 237.41 ? 90  LYS D NZ  1 
ATOM 5045 N N   . LYS D 3 88  ? 115.161 135.998 56.770  1.00 255.67 ? 91  LYS D N   1 
ATOM 5046 C CA  . LYS D 3 88  ? 116.280 136.929 56.723  1.00 255.67 ? 91  LYS D CA  1 
ATOM 5047 C C   . LYS D 3 88  ? 117.094 136.684 55.459  1.00 255.67 ? 91  LYS D C   1 
ATOM 5048 O O   . LYS D 3 88  ? 117.394 135.530 55.129  1.00 255.67 ? 91  LYS D O   1 
ATOM 5049 C CB  . LYS D 3 88  ? 117.159 136.783 57.967  1.00 255.67 ? 91  LYS D CB  1 
ATOM 5050 C CG  . LYS D 3 88  ? 118.312 137.772 58.035  1.00 255.67 ? 91  LYS D CG  1 
ATOM 5051 C CD  . LYS D 3 88  ? 119.131 137.584 59.302  1.00 255.67 ? 91  LYS D CD  1 
ATOM 5052 C CE  . LYS D 3 88  ? 120.255 138.605 59.387  1.00 255.67 ? 91  LYS D CE  1 
ATOM 5053 N NZ  . LYS D 3 88  ? 121.181 138.510 58.225  1.00 255.67 ? 91  LYS D NZ  1 
ATOM 5054 N N   . PRO D 3 89  ? 117.457 137.730 54.720  1.00 261.67 ? 92  PRO D N   1 
ATOM 5055 C CA  . PRO D 3 89  ? 118.277 137.536 53.520  1.00 261.67 ? 92  PRO D CA  1 
ATOM 5056 C C   . PRO D 3 89  ? 119.656 136.993 53.866  1.00 261.67 ? 92  PRO D C   1 
ATOM 5057 O O   . PRO D 3 89  ? 120.224 137.271 54.924  1.00 261.67 ? 92  PRO D O   1 
ATOM 5058 C CB  . PRO D 3 89  ? 118.368 138.942 52.916  1.00 261.67 ? 92  PRO D CB  1 
ATOM 5059 C CG  . PRO D 3 89  ? 118.103 139.864 54.061  1.00 261.67 ? 92  PRO D CG  1 
ATOM 5060 C CD  . PRO D 3 89  ? 117.118 139.147 54.935  1.00 261.67 ? 92  PRO D CD  1 
ATOM 5061 N N   . GLY D 3 90  ? 120.191 136.201 52.944  1.00 259.11 ? 93  GLY D N   1 
ATOM 5062 C CA  . GLY D 3 90  ? 121.486 135.561 53.105  1.00 259.11 ? 93  GLY D CA  1 
ATOM 5063 C C   . GLY D 3 90  ? 121.432 134.178 53.722  1.00 259.11 ? 93  GLY D C   1 
ATOM 5064 O O   . GLY D 3 90  ? 122.000 133.231 53.174  1.00 259.11 ? 93  GLY D O   1 
ATOM 5065 N N   . GLU D 3 91  ? 120.756 134.044 54.861  1.00 268.27 ? 94  GLU D N   1 
ATOM 5066 C CA  . GLU D 3 91  ? 120.632 132.755 55.525  1.00 268.27 ? 94  GLU D CA  1 
ATOM 5067 C C   . GLU D 3 91  ? 119.332 132.732 56.314  1.00 268.27 ? 94  GLU D C   1 
ATOM 5068 O O   . GLU D 3 91  ? 118.836 133.770 56.759  1.00 268.27 ? 94  GLU D O   1 
ATOM 5069 C CB  . GLU D 3 91  ? 121.828 132.470 56.443  1.00 268.27 ? 94  GLU D CB  1 
ATOM 5070 C CG  . GLU D 3 91  ? 121.910 133.360 57.679  1.00 268.27 ? 94  GLU D CG  1 
ATOM 5071 C CD  . GLU D 3 91  ? 122.423 134.755 57.373  1.00 268.27 ? 94  GLU D CD  1 
ATOM 5072 O OE1 . GLU D 3 91  ? 123.000 134.953 56.283  1.00 268.27 ? 94  GLU D OE1 1 
ATOM 5073 O OE2 . GLU D 3 91  ? 122.249 135.653 58.224  1.00 268.27 ? 94  GLU D OE2 1 
ATOM 5074 N N   . THR D 3 92  ? 118.788 131.529 56.481  1.00 279.44 ? 95  THR D N   1 
ATOM 5075 C CA  . THR D 3 92  ? 117.545 131.364 57.224  1.00 279.44 ? 95  THR D CA  1 
ATOM 5076 C C   . THR D 3 92  ? 117.759 131.695 58.695  1.00 279.44 ? 95  THR D C   1 
ATOM 5077 O O   . THR D 3 92  ? 118.853 131.506 59.236  1.00 279.44 ? 95  THR D O   1 
ATOM 5078 C CB  . THR D 3 92  ? 117.021 129.935 57.070  1.00 279.44 ? 95  THR D CB  1 
ATOM 5079 O OG1 . THR D 3 92  ? 115.867 129.755 57.902  1.00 279.44 ? 95  THR D OG1 1 
ATOM 5080 C CG2 . THR D 3 92  ? 118.090 128.924 57.461  1.00 279.44 ? 95  THR D CG2 1 
ATOM 5081 N N   . PHE D 3 93  ? 116.710 132.200 59.342  1.00 265.97 ? 96  PHE D N   1 
ATOM 5082 C CA  . PHE D 3 93  ? 116.769 132.612 60.740  1.00 265.97 ? 96  PHE D CA  1 
ATOM 5083 C C   . PHE D 3 93  ? 115.952 131.621 61.562  1.00 265.97 ? 96  PHE D C   1 
ATOM 5084 O O   . PHE D 3 93  ? 114.866 131.213 61.143  1.00 265.97 ? 96  PHE D O   1 
ATOM 5085 C CB  . PHE D 3 93  ? 116.238 134.037 60.895  1.00 265.97 ? 96  PHE D CB  1 
ATOM 5086 C CG  . PHE D 3 93  ? 116.752 134.762 62.109  1.00 265.97 ? 96  PHE D CG  1 
ATOM 5087 C CD1 . PHE D 3 93  ? 117.550 134.122 63.040  1.00 265.97 ? 96  PHE D CD1 1 
ATOM 5088 C CD2 . PHE D 3 93  ? 116.430 136.094 62.315  1.00 265.97 ? 96  PHE D CD2 1 
ATOM 5089 C CE1 . PHE D 3 93  ? 118.017 134.794 64.153  1.00 265.97 ? 96  PHE D CE1 1 
ATOM 5090 C CE2 . PHE D 3 93  ? 116.895 136.772 63.426  1.00 265.97 ? 96  PHE D CE2 1 
ATOM 5091 C CZ  . PHE D 3 93  ? 117.690 136.121 64.346  1.00 265.97 ? 96  PHE D CZ  1 
ATOM 5092 N N   . PHE D 3 94  ? 116.470 131.228 62.721  1.00 271.70 ? 97  PHE D N   1 
ATOM 5093 C CA  . PHE D 3 94  ? 115.688 130.522 63.724  1.00 271.70 ? 97  PHE D CA  1 
ATOM 5094 C C   . PHE D 3 94  ? 115.962 131.137 65.089  1.00 271.70 ? 97  PHE D C   1 
ATOM 5095 O O   . PHE D 3 94  ? 117.116 131.389 65.442  1.00 271.70 ? 97  PHE D O   1 
ATOM 5096 C CB  . PHE D 3 94  ? 116.018 129.027 63.738  1.00 271.70 ? 97  PHE D CB  1 
ATOM 5097 C CG  . PHE D 3 94  ? 115.323 128.243 62.661  1.00 271.70 ? 97  PHE D CG  1 
ATOM 5098 C CD1 . PHE D 3 94  ? 114.114 127.616 62.915  1.00 271.70 ? 97  PHE D CD1 1 
ATOM 5099 C CD2 . PHE D 3 94  ? 115.876 128.135 61.396  1.00 271.70 ? 97  PHE D CD2 1 
ATOM 5100 C CE1 . PHE D 3 94  ? 113.470 126.894 61.929  1.00 271.70 ? 97  PHE D CE1 1 
ATOM 5101 C CE2 . PHE D 3 94  ? 115.236 127.414 60.405  1.00 271.70 ? 97  PHE D CE2 1 
ATOM 5102 C CZ  . PHE D 3 94  ? 114.032 126.793 60.672  1.00 271.70 ? 97  PHE D CZ  1 
ATOM 5103 N N   . MET D 3 95  ? 114.903 131.384 65.854  1.00 268.71 ? 98  MET D N   1 
ATOM 5104 C CA  . MET D 3 95  ? 115.052 132.069 67.129  1.00 268.71 ? 98  MET D CA  1 
ATOM 5105 C C   . MET D 3 95  ? 114.212 131.392 68.201  1.00 268.71 ? 98  MET D C   1 
ATOM 5106 O O   . MET D 3 95  ? 113.159 130.814 67.918  1.00 268.71 ? 98  MET D O   1 
ATOM 5107 C CB  . MET D 3 95  ? 114.671 133.555 67.015  1.00 268.71 ? 98  MET D CB  1 
ATOM 5108 C CG  . MET D 3 95  ? 113.553 133.854 66.022  1.00 268.71 ? 98  MET D CG  1 
ATOM 5109 S SD  . MET D 3 95  ? 111.913 133.343 66.573  1.00 268.71 ? 98  MET D SD  1 
ATOM 5110 C CE  . MET D 3 95  ? 111.753 134.287 68.086  1.00 268.71 ? 98  MET D CE  1 
ATOM 5111 N N   . CYS D 3 96  ? 114.705 131.454 69.438  1.00 248.98 ? 99  CYS D N   1 
ATOM 5112 C CA  . CYS D 3 96  ? 113.911 131.046 70.589  1.00 248.98 ? 99  CYS D CA  1 
ATOM 5113 C C   . CYS D 3 96  ? 114.381 131.811 71.817  1.00 248.98 ? 99  CYS D C   1 
ATOM 5114 O O   . CYS D 3 96  ? 115.509 132.306 71.862  1.00 248.98 ? 99  CYS D O   1 
ATOM 5115 C CB  . CYS D 3 96  ? 113.988 129.533 70.839  1.00 248.98 ? 99  CYS D CB  1 
ATOM 5116 S SG  . CYS D 3 96  ? 115.557 128.898 71.478  1.00 248.98 ? 99  CYS D SG  1 
ATOM 5117 N N   . SER D 3 97  ? 113.504 131.896 72.817  1.00 234.72 ? 100 SER D N   1 
ATOM 5118 C CA  . SER D 3 97  ? 113.813 132.572 74.069  1.00 234.72 ? 100 SER D CA  1 
ATOM 5119 C C   . SER D 3 97  ? 113.127 131.853 75.223  1.00 234.72 ? 100 SER D C   1 
ATOM 5120 O O   . SER D 3 97  ? 112.102 131.191 75.042  1.00 234.72 ? 100 SER D O   1 
ATOM 5121 C CB  . SER D 3 97  ? 113.383 134.045 74.036  1.00 234.72 ? 100 SER D CB  1 
ATOM 5122 O OG  . SER D 3 97  ? 114.042 134.746 72.995  1.00 234.72 ? 100 SER D OG  1 
ATOM 5123 N N   . CYS D 3 98  ? 113.707 131.995 76.414  1.00 191.27 ? 101 CYS D N   1 
ATOM 5124 C CA  . CYS D 3 98  ? 113.182 131.340 77.604  1.00 191.27 ? 101 CYS D CA  1 
ATOM 5125 C C   . CYS D 3 98  ? 113.608 132.119 78.843  1.00 191.27 ? 101 CYS D C   1 
ATOM 5126 O O   . CYS D 3 98  ? 114.698 132.698 78.877  1.00 191.27 ? 101 CYS D O   1 
ATOM 5127 C CB  . CYS D 3 98  ? 113.654 129.884 77.688  1.00 191.27 ? 101 CYS D CB  1 
ATOM 5128 S SG  . CYS D 3 98  ? 115.437 129.672 77.860  1.00 191.27 ? 101 CYS D SG  1 
ATOM 5129 N N   . SER D 3 99  ? 112.749 132.112 79.864  1.00 171.20 ? 102 SER D N   1 
ATOM 5130 C CA  . SER D 3 99  ? 112.910 132.964 81.036  1.00 171.20 ? 102 SER D CA  1 
ATOM 5131 C C   . SER D 3 99  ? 113.281 132.208 82.308  1.00 171.20 ? 102 SER D C   1 
ATOM 5132 O O   . SER D 3 99  ? 113.489 132.845 83.345  1.00 171.20 ? 102 SER D O   1 
ATOM 5133 C CB  . SER D 3 99  ? 111.626 133.765 81.279  1.00 171.20 ? 102 SER D CB  1 
ATOM 5134 O OG  . SER D 3 99  ? 111.730 134.546 82.457  1.00 171.20 ? 102 SER D OG  1 
ATOM 5135 N N   . SER D 3 100 ? 113.364 130.881 82.268  1.00 115.59 ? 103 SER D N   1 
ATOM 5136 C CA  . SER D 3 100 ? 113.750 130.134 83.454  1.00 115.59 ? 103 SER D CA  1 
ATOM 5137 C C   . SER D 3 100 ? 115.273 130.031 83.536  1.00 115.59 ? 103 SER D C   1 
ATOM 5138 O O   . SER D 3 100 ? 116.009 130.640 82.756  1.00 115.59 ? 103 SER D O   1 
ATOM 5139 C CB  . SER D 3 100 ? 113.095 128.755 83.456  1.00 115.59 ? 103 SER D CB  1 
ATOM 5140 O OG  . SER D 3 100 ? 113.518 127.982 82.349  1.00 115.59 ? 103 SER D OG  1 
ATOM 5141 N N   . ASP D 3 101 ? 115.755 129.245 84.493  1.00 119.97 ? 104 ASP D N   1 
ATOM 5142 C CA  . ASP D 3 101 ? 117.181 129.163 84.785  1.00 119.97 ? 104 ASP D CA  1 
ATOM 5143 C C   . ASP D 3 101 ? 117.822 128.080 83.927  1.00 119.97 ? 104 ASP D C   1 
ATOM 5144 O O   . ASP D 3 101 ? 117.339 126.943 83.893  1.00 119.97 ? 104 ASP D O   1 
ATOM 5145 C CB  . ASP D 3 101 ? 117.412 128.880 86.270  1.00 119.97 ? 104 ASP D CB  1 
ATOM 5146 C CG  . ASP D 3 101 ? 116.671 129.851 87.172  1.00 119.97 ? 104 ASP D CG  1 
ATOM 5147 O OD1 . ASP D 3 101 ? 115.494 129.585 87.495  1.00 119.97 ? 104 ASP D OD1 1 
ATOM 5148 O OD2 . ASP D 3 101 ? 117.260 130.883 87.550  1.00 119.97 ? 104 ASP D OD2 1 
ATOM 5149 N N   . GLU D 3 102 ? 118.908 128.438 83.240  1.00 138.42 ? 105 GLU D N   1 
ATOM 5150 C CA  . GLU D 3 102 ? 119.690 127.502 82.430  1.00 138.42 ? 105 GLU D CA  1 
ATOM 5151 C C   . GLU D 3 102 ? 118.817 126.746 81.430  1.00 138.42 ? 105 GLU D C   1 
ATOM 5152 O O   . GLU D 3 102 ? 118.982 125.540 81.229  1.00 138.42 ? 105 GLU D O   1 
ATOM 5153 C CB  . GLU D 3 102 ? 120.463 126.520 83.315  1.00 138.42 ? 105 GLU D CB  1 
ATOM 5154 C CG  . GLU D 3 102 ? 121.764 126.022 82.705  1.00 138.42 ? 105 GLU D CG  1 
ATOM 5155 C CD  . GLU D 3 102 ? 122.453 124.984 83.569  1.00 138.42 ? 105 GLU D CD  1 
ATOM 5156 O OE1 . GLU D 3 102 ? 121.751 124.264 84.309  1.00 138.42 ? 105 GLU D OE1 1 
ATOM 5157 O OE2 . GLU D 3 102 ? 123.698 124.890 83.512  1.00 138.42 ? 105 GLU D OE2 1 
ATOM 5158 N N   . CYS D 3 103 ? 117.878 127.449 80.796  1.00 208.84 ? 106 CYS D N   1 
ATOM 5159 C CA  . CYS D 3 103 ? 116.914 126.810 79.910  1.00 208.84 ? 106 CYS D CA  1 
ATOM 5160 C C   . CYS D 3 103 ? 117.367 126.755 78.456  1.00 208.84 ? 106 CYS D C   1 
ATOM 5161 O O   . CYS D 3 103 ? 116.687 126.122 77.642  1.00 208.84 ? 106 CYS D O   1 
ATOM 5162 C CB  . CYS D 3 103 ? 115.571 127.536 80.002  1.00 208.84 ? 106 CYS D CB  1 
ATOM 5163 S SG  . CYS D 3 103 ? 115.683 129.333 79.846  1.00 208.84 ? 106 CYS D SG  1 
ATOM 5164 N N   . ASN D 3 104 ? 118.481 127.392 78.109  1.00 213.20 ? 107 ASN D N   1 
ATOM 5165 C CA  . ASN D 3 104 ? 118.972 127.392 76.738  1.00 213.20 ? 107 ASN D CA  1 
ATOM 5166 C C   . ASN D 3 104 ? 120.089 126.383 76.504  1.00 213.20 ? 107 ASN D C   1 
ATOM 5167 O O   . ASN D 3 104 ? 120.697 126.395 75.428  1.00 213.20 ? 107 ASN D O   1 
ATOM 5168 C CB  . ASN D 3 104 ? 119.450 128.794 76.346  1.00 213.20 ? 107 ASN D CB  1 
ATOM 5169 C CG  . ASN D 3 104 ? 120.525 129.324 77.271  1.00 213.20 ? 107 ASN D CG  1 
ATOM 5170 O OD1 . ASN D 3 104 ? 120.579 128.968 78.448  1.00 213.20 ? 107 ASN D OD1 1 
ATOM 5171 N ND2 . ASN D 3 104 ? 121.387 130.186 76.743  1.00 213.20 ? 107 ASN D ND2 1 
ATOM 5172 N N   . ASP D 3 105 ? 120.379 125.522 77.482  1.00 202.02 ? 108 ASP D N   1 
ATOM 5173 C CA  . ASP D 3 105 ? 121.427 124.520 77.304  1.00 202.02 ? 108 ASP D CA  1 
ATOM 5174 C C   . ASP D 3 105 ? 121.062 123.528 76.205  1.00 202.02 ? 108 ASP D C   1 
ATOM 5175 O O   . ASP D 3 105 ? 121.907 123.152 75.385  1.00 202.02 ? 108 ASP D O   1 
ATOM 5176 C CB  . ASP D 3 105 ? 121.688 123.797 78.626  1.00 202.02 ? 108 ASP D CB  1 
ATOM 5177 C CG  . ASP D 3 105 ? 120.431 123.188 79.217  1.00 202.02 ? 108 ASP D CG  1 
ATOM 5178 O OD1 . ASP D 3 105 ? 119.331 123.720 78.954  1.00 202.02 ? 108 ASP D OD1 1 
ATOM 5179 O OD2 . ASP D 3 105 ? 120.542 122.178 79.944  1.00 202.02 ? 108 ASP D OD2 1 
ATOM 5180 N N   . ASN D 3 106 ? 119.807 123.092 76.174  1.00 217.96 ? 109 ASN D N   1 
ATOM 5181 C CA  . ASN D 3 106 ? 119.320 122.170 75.160  1.00 217.96 ? 109 ASN D CA  1 
ATOM 5182 C C   . ASN D 3 106 ? 118.310 122.868 74.259  1.00 217.96 ? 109 ASN D C   1 
ATOM 5183 O O   . ASN D 3 106 ? 117.405 123.561 74.731  1.00 217.96 ? 109 ASN D O   1 
ATOM 5184 C CB  . ASN D 3 106 ? 118.680 120.937 75.803  1.00 217.96 ? 109 ASN D CB  1 
ATOM 5185 C CG  . ASN D 3 106 ? 119.618 120.221 76.753  1.00 217.96 ? 109 ASN D CG  1 
ATOM 5186 O OD1 . ASN D 3 106 ? 120.835 120.230 76.567  1.00 217.96 ? 109 ASN D OD1 1 
ATOM 5187 N ND2 . ASN D 3 106 ? 119.055 119.594 77.779  1.00 217.96 ? 109 ASN D ND2 1 
ATOM 5188 N N   . ILE D 3 107 ? 118.470 122.677 72.952  1.00 266.68 ? 110 ILE D N   1 
ATOM 5189 C CA  . ILE D 3 107 ? 117.620 123.304 71.948  1.00 266.68 ? 110 ILE D CA  1 
ATOM 5190 C C   . ILE D 3 107 ? 116.654 122.246 71.436  1.00 266.68 ? 110 ILE D C   1 
ATOM 5191 O O   . ILE D 3 107 ? 117.078 121.166 71.003  1.00 266.68 ? 110 ILE D O   1 
ATOM 5192 C CB  . ILE D 3 107 ? 118.443 123.908 70.797  1.00 266.68 ? 110 ILE D CB  1 
ATOM 5193 C CG1 . ILE D 3 107 ? 118.911 125.326 71.146  1.00 266.68 ? 110 ILE D CG1 1 
ATOM 5194 C CG2 . ILE D 3 107 ? 117.647 123.912 69.501  1.00 266.68 ? 110 ILE D CG2 1 
ATOM 5195 C CD1 . ILE D 3 107 ? 120.029 125.384 72.167  1.00 266.68 ? 110 ILE D CD1 1 
ATOM 5196 N N   . ILE D 3 108 ? 115.359 122.544 71.504  1.00 270.08 ? 111 ILE D N   1 
ATOM 5197 C CA  . ILE D 3 108 ? 114.315 121.647 71.025  1.00 270.08 ? 111 ILE D CA  1 
ATOM 5198 C C   . ILE D 3 108 ? 113.621 122.320 69.848  1.00 270.08 ? 111 ILE D C   1 
ATOM 5199 O O   . ILE D 3 108 ? 113.015 123.389 69.998  1.00 270.08 ? 111 ILE D O   1 
ATOM 5200 C CB  . ILE D 3 108 ? 113.321 121.283 72.141  1.00 270.08 ? 111 ILE D CB  1 
ATOM 5201 C CG1 . ILE D 3 108 ? 112.108 120.549 71.564  1.00 270.08 ? 111 ILE D CG1 1 
ATOM 5202 C CG2 . ILE D 3 108 ? 112.915 122.516 72.948  1.00 270.08 ? 111 ILE D CG2 1 
ATOM 5203 C CD1 . ILE D 3 108 ? 112.442 119.188 70.995  1.00 270.08 ? 111 ILE D CD1 1 
ATOM 5204 N N   . PHE D 3 109 ? 113.726 121.702 68.671  1.00 260.25 ? 112 PHE D N   1 
ATOM 5205 C CA  . PHE D 3 109 ? 113.153 122.297 67.468  1.00 260.25 ? 112 PHE D CA  1 
ATOM 5206 C C   . PHE D 3 109 ? 111.636 122.151 67.442  1.00 260.25 ? 112 PHE D C   1 
ATOM 5207 O O   . PHE D 3 109 ? 110.923 123.091 67.069  1.00 260.25 ? 112 PHE D O   1 
ATOM 5208 C CB  . PHE D 3 109 ? 113.781 121.669 66.225  1.00 260.25 ? 112 PHE D CB  1 
ATOM 5209 C CG  . PHE D 3 109 ? 115.260 121.914 66.105  1.00 260.25 ? 112 PHE D CG  1 
ATOM 5210 C CD1 . PHE D 3 109 ? 116.169 121.098 66.760  1.00 260.25 ? 112 PHE D CD1 1 
ATOM 5211 C CD2 . PHE D 3 109 ? 115.742 122.961 65.338  1.00 260.25 ? 112 PHE D CD2 1 
ATOM 5212 C CE1 . PHE D 3 109 ? 117.528 121.321 66.652  1.00 260.25 ? 112 PHE D CE1 1 
ATOM 5213 C CE2 . PHE D 3 109 ? 117.101 123.189 65.227  1.00 260.25 ? 112 PHE D CE2 1 
ATOM 5214 C CZ  . PHE D 3 109 ? 117.995 122.368 65.884  1.00 260.25 ? 112 PHE D CZ  1 
ATOM 5215 N N   . SER D 3 110 ? 111.124 120.987 67.835  1.00 265.35 ? 113 SER D N   1 
ATOM 5216 C CA  . SER D 3 110 ? 109.689 120.742 67.837  1.00 265.35 ? 113 SER D CA  1 
ATOM 5217 C C   . SER D 3 110 ? 109.389 119.577 68.767  1.00 265.35 ? 113 SER D C   1 
ATOM 5218 O O   . SER D 3 110 ? 110.148 118.606 68.814  1.00 265.35 ? 113 SER D O   1 
ATOM 5219 C CB  . SER D 3 110 ? 109.173 120.440 66.423  1.00 265.35 ? 113 SER D CB  1 
ATOM 5220 O OG  . SER D 3 110 ? 109.802 119.290 65.885  1.00 265.35 ? 113 SER D OG  1 
ATOM 5221 N N   . GLU D 3 111 ? 108.276 119.680 69.498  1.00 257.93 ? 114 GLU D N   1 
ATOM 5222 C CA  . GLU D 3 111 ? 107.893 118.625 70.429  1.00 257.93 ? 114 GLU D CA  1 
ATOM 5223 C C   . GLU D 3 111 ? 107.463 117.349 69.719  1.00 257.93 ? 114 GLU D C   1 
ATOM 5224 O O   . GLU D 3 111 ? 107.327 116.308 70.372  1.00 257.93 ? 114 GLU D O   1 
ATOM 5225 C CB  . GLU D 3 111 ? 106.770 119.113 71.347  1.00 257.93 ? 114 GLU D CB  1 
ATOM 5226 C CG  . GLU D 3 111 ? 107.246 119.889 72.567  1.00 257.93 ? 114 GLU D CG  1 
ATOM 5227 C CD  . GLU D 3 111 ? 107.905 121.208 72.212  1.00 257.93 ? 114 GLU D CD  1 
ATOM 5228 O OE1 . GLU D 3 111 ? 107.578 121.774 71.147  1.00 257.93 ? 114 GLU D OE1 1 
ATOM 5229 O OE2 . GLU D 3 111 ? 108.753 121.677 72.999  1.00 257.93 ? 114 GLU D OE2 1 
ATOM 5230 N N   . GLU D 3 112 ? 107.234 117.405 68.408  1.00 265.49 ? 115 GLU D N   1 
ATOM 5231 C CA  . GLU D 3 112 ? 106.849 116.215 67.661  1.00 265.49 ? 115 GLU D CA  1 
ATOM 5232 C C   . GLU D 3 112 ? 107.955 115.168 67.718  1.00 265.49 ? 115 GLU D C   1 
ATOM 5233 O O   . GLU D 3 112 ? 109.133 115.478 67.522  1.00 265.49 ? 115 GLU D O   1 
ATOM 5234 C CB  . GLU D 3 112 ? 106.539 116.582 66.211  1.00 265.49 ? 115 GLU D CB  1 
ATOM 5235 C CG  . GLU D 3 112 ? 105.430 117.610 66.055  1.00 265.49 ? 115 GLU D CG  1 
ATOM 5236 C CD  . GLU D 3 112 ? 105.181 117.983 64.606  1.00 265.49 ? 115 GLU D CD  1 
ATOM 5237 O OE1 . GLU D 3 112 ? 105.865 117.426 63.722  1.00 265.49 ? 115 GLU D OE1 1 
ATOM 5238 O OE2 . GLU D 3 112 ? 104.302 118.833 64.352  1.00 265.49 ? 115 GLU D OE2 1 
ATOM 5239 N N   . TYR D 3 113 ? 107.569 113.925 67.988  1.00 278.50 ? 116 TYR D N   1 
ATOM 5240 C CA  . TYR D 3 113 ? 108.527 112.830 68.087  1.00 278.50 ? 116 TYR D CA  1 
ATOM 5241 C C   . TYR D 3 113 ? 107.989 111.592 67.375  1.00 278.50 ? 116 TYR D C   1 
ATOM 5242 O O   . TYR D 3 113 ? 108.730 110.861 66.718  0.00 278.50 ? 116 TYR D O   1 
ATOM 5243 C CB  . TYR D 3 113 ? 108.829 112.514 69.554  1.00 278.50 ? 116 TYR D CB  1 
ATOM 5244 C CG  . TYR D 3 113 ? 110.153 111.817 69.789  1.00 278.50 ? 116 TYR D CG  1 
ATOM 5245 C CD1 . TYR D 3 113 ? 111.003 111.516 68.732  1.00 278.50 ? 116 TYR D CD1 1 
ATOM 5246 C CD2 . TYR D 3 113 ? 110.551 111.458 71.070  1.00 278.50 ? 116 TYR D CD2 1 
ATOM 5247 C CE1 . TYR D 3 113 ? 112.212 110.879 68.945  1.00 278.50 ? 116 TYR D CE1 1 
ATOM 5248 C CE2 . TYR D 3 113 ? 111.757 110.821 71.293  1.00 278.50 ? 116 TYR D CE2 1 
ATOM 5249 C CZ  . TYR D 3 113 ? 112.583 110.534 70.228  1.00 278.50 ? 116 TYR D CZ  1 
ATOM 5250 O OH  . TYR D 3 113 ? 113.785 109.900 70.445  1.00 278.50 ? 116 TYR D OH  1 
ATOM 5251 O OXT . TYR D 3 113 ? 106.796 111.297 67.437  0.00 278.50 ? 116 TYR D OXT 1 
ATOM 5252 N N   . VAL E 3 5   ? 147.836 110.661 142.909 1.00 139.31 ? 8   VAL E N   1 
ATOM 5253 C CA  . VAL E 3 5   ? 147.102 111.910 142.756 1.00 139.31 ? 8   VAL E CA  1 
ATOM 5254 C C   . VAL E 3 5   ? 147.561 112.927 143.800 1.00 139.31 ? 8   VAL E C   1 
ATOM 5255 O O   . VAL E 3 5   ? 147.578 112.642 144.998 1.00 139.31 ? 8   VAL E O   1 
ATOM 5256 C CB  . VAL E 3 5   ? 145.577 111.671 142.838 1.00 139.31 ? 8   VAL E CB  1 
ATOM 5257 C CG1 . VAL E 3 5   ? 145.231 110.795 144.036 1.00 139.31 ? 8   VAL E CG1 1 
ATOM 5258 C CG2 . VAL E 3 5   ? 144.829 112.994 142.901 1.00 139.31 ? 8   VAL E CG2 1 
ATOM 5259 N N   . LYS E 3 6   ? 147.947 114.112 143.332 1.00 125.56 ? 9   LYS E N   1 
ATOM 5260 C CA  . LYS E 3 6   ? 148.407 115.186 144.200 1.00 125.56 ? 9   LYS E CA  1 
ATOM 5261 C C   . LYS E 3 6   ? 147.287 116.136 144.605 1.00 125.56 ? 9   LYS E C   1 
ATOM 5262 O O   . LYS E 3 6   ? 147.543 117.102 145.330 1.00 125.56 ? 9   LYS E O   1 
ATOM 5263 C CB  . LYS E 3 6   ? 149.532 115.977 143.522 1.00 125.56 ? 9   LYS E CB  1 
ATOM 5264 C CG  . LYS E 3 6   ? 150.831 115.204 143.329 1.00 125.56 ? 9   LYS E CG  1 
ATOM 5265 C CD  . LYS E 3 6   ? 150.837 114.420 142.025 1.00 125.56 ? 9   LYS E CD  1 
ATOM 5266 C CE  . LYS E 3 6   ? 152.141 113.660 141.844 1.00 125.56 ? 9   LYS E CE  1 
ATOM 5267 N NZ  . LYS E 3 6   ? 152.154 112.867 140.584 1.00 125.56 ? 9   LYS E NZ  1 
ATOM 5268 N N   . PHE E 3 7   ? 146.061 115.888 144.152 1.00 119.70 ? 10  PHE E N   1 
ATOM 5269 C CA  . PHE E 3 7   ? 144.945 116.741 144.520 1.00 119.70 ? 10  PHE E CA  1 
ATOM 5270 C C   . PHE E 3 7   ? 144.639 116.602 146.010 1.00 119.70 ? 10  PHE E C   1 
ATOM 5271 O O   . PHE E 3 7   ? 144.821 115.530 146.592 1.00 119.70 ? 10  PHE E O   1 
ATOM 5272 C CB  . PHE E 3 7   ? 143.710 116.390 143.697 1.00 119.70 ? 10  PHE E CB  1 
ATOM 5273 C CG  . PHE E 3 7   ? 143.821 116.774 142.251 1.00 119.70 ? 10  PHE E CG  1 
ATOM 5274 C CD1 . PHE E 3 7   ? 144.524 117.907 141.876 1.00 119.70 ? 10  PHE E CD1 1 
ATOM 5275 C CD2 . PHE E 3 7   ? 143.230 116.000 141.266 1.00 119.70 ? 10  PHE E CD2 1 
ATOM 5276 C CE1 . PHE E 3 7   ? 144.631 118.266 140.546 1.00 119.70 ? 10  PHE E CE1 1 
ATOM 5277 C CE2 . PHE E 3 7   ? 143.334 116.353 139.933 1.00 119.70 ? 10  PHE E CE2 1 
ATOM 5278 C CZ  . PHE E 3 7   ? 144.036 117.487 139.573 1.00 119.70 ? 10  PHE E CZ  1 
ATOM 5279 N N   . PRO E 3 8   ? 144.181 117.675 146.650 1.00 80.29  ? 11  PRO E N   1 
ATOM 5280 C CA  . PRO E 3 8   ? 143.891 117.605 148.084 1.00 80.29  ? 11  PRO E CA  1 
ATOM 5281 C C   . PRO E 3 8   ? 142.735 116.663 148.373 1.00 80.29  ? 11  PRO E C   1 
ATOM 5282 O O   . PRO E 3 8   ? 141.858 116.440 147.536 1.00 80.29  ? 11  PRO E O   1 
ATOM 5283 C CB  . PRO E 3 8   ? 143.538 119.051 148.443 1.00 80.29  ? 11  PRO E CB  1 
ATOM 5284 C CG  . PRO E 3 8   ? 143.057 119.637 147.166 1.00 80.29  ? 11  PRO E CG  1 
ATOM 5285 C CD  . PRO E 3 8   ? 143.886 119.005 146.093 1.00 80.29  ? 11  PRO E CD  1 
ATOM 5286 N N   . GLN E 3 9   ? 142.750 116.099 149.578 1.00 74.10  ? 12  GLN E N   1 
ATOM 5287 C CA  . GLN E 3 9   ? 141.711 115.165 149.983 1.00 74.10  ? 12  GLN E CA  1 
ATOM 5288 C C   . GLN E 3 9   ? 140.361 115.862 150.096 1.00 74.10  ? 12  GLN E C   1 
ATOM 5289 O O   . GLN E 3 9   ? 140.273 117.063 150.359 1.00 74.10  ? 12  GLN E O   1 
ATOM 5290 C CB  . GLN E 3 9   ? 142.059 114.522 151.326 1.00 74.10  ? 12  GLN E CB  1 
ATOM 5291 C CG  . GLN E 3 9   ? 142.808 113.215 151.218 1.00 74.10  ? 12  GLN E CG  1 
ATOM 5292 C CD  . GLN E 3 9   ? 144.259 113.405 150.848 1.00 74.10  ? 12  GLN E CD  1 
ATOM 5293 O OE1 . GLN E 3 9   ? 144.865 114.429 151.166 1.00 74.10  ? 12  GLN E OE1 1 
ATOM 5294 N NE2 . GLN E 3 9   ? 144.826 112.421 150.159 1.00 74.10  ? 12  GLN E NE2 1 
ATOM 5295 N N   . LEU E 3 10  ? 139.302 115.089 149.886 1.00 63.43  ? 13  LEU E N   1 
ATOM 5296 C CA  . LEU E 3 10  ? 137.953 115.507 150.232 1.00 63.43  ? 13  LEU E CA  1 
ATOM 5297 C C   . LEU E 3 10  ? 137.612 114.899 151.584 1.00 63.43  ? 13  LEU E C   1 
ATOM 5298 O O   . LEU E 3 10  ? 137.605 113.674 151.729 1.00 63.43  ? 13  LEU E O   1 
ATOM 5299 C CB  . LEU E 3 10  ? 136.948 115.050 149.177 1.00 63.43  ? 13  LEU E CB  1 
ATOM 5300 C CG  . LEU E 3 10  ? 137.251 115.369 147.718 1.00 63.43  ? 13  LEU E CG  1 
ATOM 5301 C CD1 . LEU E 3 10  ? 136.297 114.621 146.817 1.00 63.43  ? 13  LEU E CD1 1 
ATOM 5302 C CD2 . LEU E 3 10  ? 137.141 116.848 147.478 1.00 63.43  ? 13  LEU E CD2 1 
ATOM 5303 N N   . CYS E 3 11  ? 137.342 115.744 152.573 1.00 61.55  ? 14  CYS E N   1 
ATOM 5304 C CA  . CYS E 3 11  ? 137.029 115.268 153.910 1.00 61.55  ? 14  CYS E CA  1 
ATOM 5305 C C   . CYS E 3 11  ? 135.772 115.949 154.419 1.00 61.55  ? 14  CYS E C   1 
ATOM 5306 O O   . CYS E 3 11  ? 135.526 117.120 154.132 1.00 61.55  ? 14  CYS E O   1 
ATOM 5307 C CB  . CYS E 3 11  ? 138.169 115.540 154.894 1.00 61.55  ? 14  CYS E CB  1 
ATOM 5308 S SG  . CYS E 3 11  ? 139.789 114.948 154.390 1.00 61.55  ? 14  CYS E SG  1 
ATOM 5309 N N   . LYS E 3 12  ? 134.972 115.210 155.176 1.00 63.61  ? 15  LYS E N   1 
ATOM 5310 C CA  . LYS E 3 12  ? 133.919 115.856 155.941 1.00 63.61  ? 15  LYS E CA  1 
ATOM 5311 C C   . LYS E 3 12  ? 134.573 116.763 156.971 1.00 63.61  ? 15  LYS E C   1 
ATOM 5312 O O   . LYS E 3 12  ? 135.517 116.357 157.651 1.00 63.61  ? 15  LYS E O   1 
ATOM 5313 C CB  . LYS E 3 12  ? 133.025 114.819 156.613 1.00 63.61  ? 15  LYS E CB  1 
ATOM 5314 C CG  . LYS E 3 12  ? 132.228 113.964 155.646 1.00 63.61  ? 15  LYS E CG  1 
ATOM 5315 C CD  . LYS E 3 12  ? 131.305 114.817 154.799 1.00 63.61  ? 15  LYS E CD  1 
ATOM 5316 C CE  . LYS E 3 12  ? 130.476 113.964 153.860 1.00 63.61  ? 15  LYS E CE  1 
ATOM 5317 N NZ  . LYS E 3 12  ? 129.678 112.953 154.600 1.00 63.61  ? 15  LYS E NZ  1 
ATOM 5318 N N   . PHE E 3 13  ? 134.103 118.001 157.066 1.00 60.66  ? 16  PHE E N   1 
ATOM 5319 C CA  . PHE E 3 13  ? 134.746 118.998 157.914 1.00 60.66  ? 16  PHE E CA  1 
ATOM 5320 C C   . PHE E 3 13  ? 133.718 119.702 158.782 1.00 60.66  ? 16  PHE E C   1 
ATOM 5321 O O   . PHE E 3 13  ? 133.675 120.930 158.874 1.00 60.66  ? 16  PHE E O   1 
ATOM 5322 C CB  . PHE E 3 13  ? 135.532 120.002 157.080 1.00 60.66  ? 16  PHE E CB  1 
ATOM 5323 C CG  . PHE E 3 13  ? 136.717 120.592 157.793 1.00 60.66  ? 16  PHE E CG  1 
ATOM 5324 C CD1 . PHE E 3 13  ? 136.723 120.734 159.166 1.00 60.66  ? 16  PHE E CD1 1 
ATOM 5325 C CD2 . PHE E 3 13  ? 137.832 120.995 157.084 1.00 60.66  ? 16  PHE E CD2 1 
ATOM 5326 C CE1 . PHE E 3 13  ? 137.806 121.275 159.812 1.00 60.66  ? 16  PHE E CE1 1 
ATOM 5327 C CE2 . PHE E 3 13  ? 138.920 121.535 157.728 1.00 60.66  ? 16  PHE E CE2 1 
ATOM 5328 C CZ  . PHE E 3 13  ? 138.907 121.673 159.093 1.00 60.66  ? 16  PHE E CZ  1 
ATOM 5329 N N   . CYS E 3 14  ? 132.860 118.923 159.427 1.00 83.17  ? 17  CYS E N   1 
ATOM 5330 C CA  . CYS E 3 14  ? 132.039 119.456 160.500 1.00 83.17  ? 17  CYS E CA  1 
ATOM 5331 C C   . CYS E 3 14  ? 132.839 119.464 161.794 1.00 83.17  ? 17  CYS E C   1 
ATOM 5332 O O   . CYS E 3 14  ? 133.565 118.514 162.098 1.00 83.17  ? 17  CYS E O   1 
ATOM 5333 C CB  . CYS E 3 14  ? 130.768 118.628 160.678 1.00 83.17  ? 17  CYS E CB  1 
ATOM 5334 S SG  . CYS E 3 14  ? 129.643 118.687 159.283 1.00 83.17  ? 17  CYS E SG  1 
ATOM 5335 N N   . ASP E 3 15  ? 132.696 120.535 162.562 1.00 88.89  ? 18  ASP E N   1 
ATOM 5336 C CA  . ASP E 3 15  ? 133.367 120.631 163.848 1.00 88.89  ? 18  ASP E CA  1 
ATOM 5337 C C   . ASP E 3 15  ? 132.625 119.761 164.860 1.00 88.89  ? 18  ASP E C   1 
ATOM 5338 O O   . ASP E 3 15  ? 131.837 118.882 164.501 1.00 88.89  ? 18  ASP E O   1 
ATOM 5339 C CB  . ASP E 3 15  ? 133.467 122.089 164.284 1.00 88.89  ? 18  ASP E CB  1 
ATOM 5340 C CG  . ASP E 3 15  ? 134.339 122.910 163.357 1.00 88.89  ? 18  ASP E CG  1 
ATOM 5341 O OD1 . ASP E 3 15  ? 135.291 122.342 162.781 1.00 88.89  ? 18  ASP E OD1 1 
ATOM 5342 O OD2 . ASP E 3 15  ? 134.071 124.119 163.200 1.00 88.89  ? 18  ASP E OD2 1 
ATOM 5343 N N   . VAL E 3 16  ? 132.892 119.980 166.148 1.00 95.78  ? 19  VAL E N   1 
ATOM 5344 C CA  . VAL E 3 16  ? 132.260 119.179 167.187 1.00 95.78  ? 19  VAL E CA  1 
ATOM 5345 C C   . VAL E 3 16  ? 130.749 119.303 167.077 1.00 95.78  ? 19  VAL E C   1 
ATOM 5346 O O   . VAL E 3 16  ? 130.185 120.389 167.248 1.00 95.78  ? 19  VAL E O   1 
ATOM 5347 C CB  . VAL E 3 16  ? 132.766 119.621 168.571 1.00 95.78  ? 19  VAL E CB  1 
ATOM 5348 C CG1 . VAL E 3 16  ? 131.994 118.916 169.667 1.00 95.78  ? 19  VAL E CG1 1 
ATOM 5349 C CG2 . VAL E 3 16  ? 134.259 119.353 168.701 1.00 95.78  ? 19  VAL E CG2 1 
ATOM 5350 N N   . ARG E 3 17  ? 130.087 118.184 166.786 1.00 97.42  ? 20  ARG E N   1 
ATOM 5351 C CA  . ARG E 3 17  ? 128.640 118.163 166.632 1.00 97.42  ? 20  ARG E CA  1 
ATOM 5352 C C   . ARG E 3 17  ? 128.089 116.883 167.238 1.00 97.42  ? 20  ARG E C   1 
ATOM 5353 O O   . ARG E 3 17  ? 128.780 115.864 167.309 1.00 97.42  ? 20  ARG E O   1 
ATOM 5354 C CB  . ARG E 3 17  ? 128.223 118.278 165.161 1.00 97.42  ? 20  ARG E CB  1 
ATOM 5355 C CG  . ARG E 3 17  ? 128.481 119.644 164.550 1.00 97.42  ? 20  ARG E CG  1 
ATOM 5356 C CD  . ARG E 3 17  ? 127.873 119.764 163.166 1.00 97.42  ? 20  ARG E CD  1 
ATOM 5357 N NE  . ARG E 3 17  ? 127.987 121.122 162.649 1.00 97.42  ? 20  ARG E NE  1 
ATOM 5358 C CZ  . ARG E 3 17  ? 127.474 121.533 161.498 1.00 97.42  ? 20  ARG E CZ  1 
ATOM 5359 N NH1 . ARG E 3 17  ? 126.803 120.711 160.708 1.00 97.42  ? 20  ARG E NH1 1 
ATOM 5360 N NH2 . ARG E 3 17  ? 127.637 122.801 161.131 1.00 97.42  ? 20  ARG E NH2 1 
ATOM 5361 N N   . PHE E 3 18  ? 126.831 116.944 167.668 1.00 120.24 ? 21  PHE E N   1 
ATOM 5362 C CA  . PHE E 3 18  ? 126.205 115.823 168.356 1.00 120.24 ? 21  PHE E CA  1 
ATOM 5363 C C   . PHE E 3 18  ? 125.726 114.780 167.356 1.00 120.24 ? 21  PHE E C   1 
ATOM 5364 O O   . PHE E 3 18  ? 125.237 115.119 166.274 1.00 120.24 ? 21  PHE E O   1 
ATOM 5365 C CB  . PHE E 3 18  ? 125.037 116.310 169.212 1.00 120.24 ? 21  PHE E CB  1 
ATOM 5366 C CG  . PHE E 3 18  ? 125.408 117.390 170.186 1.00 120.24 ? 21  PHE E CG  1 
ATOM 5367 C CD1 . PHE E 3 18  ? 125.172 118.722 169.887 1.00 120.24 ? 21  PHE E CD1 1 
ATOM 5368 C CD2 . PHE E 3 18  ? 125.996 117.075 171.399 1.00 120.24 ? 21  PHE E CD2 1 
ATOM 5369 C CE1 . PHE E 3 18  ? 125.513 119.719 170.781 1.00 120.24 ? 21  PHE E CE1 1 
ATOM 5370 C CE2 . PHE E 3 18  ? 126.340 118.066 172.297 1.00 120.24 ? 21  PHE E CE2 1 
ATOM 5371 C CZ  . PHE E 3 18  ? 126.098 119.390 171.988 1.00 120.24 ? 21  PHE E CZ  1 
ATOM 5372 N N   . SER E 3 19  ? 125.871 113.507 167.723 1.00 121.87 ? 22  SER E N   1 
ATOM 5373 C CA  . SER E 3 19  ? 125.386 112.404 166.902 1.00 121.87 ? 22  SER E CA  1 
ATOM 5374 C C   . SER E 3 19  ? 124.493 111.496 167.735 1.00 121.87 ? 22  SER E C   1 
ATOM 5375 O O   . SER E 3 19  ? 124.129 111.843 168.863 1.00 121.87 ? 22  SER E O   1 
ATOM 5376 C CB  . SER E 3 19  ? 126.551 111.610 166.312 1.00 121.87 ? 22  SER E CB  1 
ATOM 5377 O OG  . SER E 3 19  ? 127.216 110.863 167.315 1.00 121.87 ? 22  SER E OG  1 
ATOM 5378 N N   . THR E 3 20  ? 124.129 110.336 167.192 1.00 130.53 ? 23  THR E N   1 
ATOM 5379 C CA  . THR E 3 20  ? 123.246 109.421 167.904 1.00 130.53 ? 23  THR E CA  1 
ATOM 5380 C C   . THR E 3 20  ? 123.846 108.023 168.004 1.00 130.53 ? 23  THR E C   1 
ATOM 5381 O O   . THR E 3 20  ? 123.537 107.277 168.937 1.00 130.53 ? 23  THR E O   1 
ATOM 5382 C CB  . THR E 3 20  ? 121.879 109.354 167.218 1.00 130.53 ? 23  THR E CB  1 
ATOM 5383 O OG1 . THR E 3 20  ? 122.047 108.965 165.849 1.00 130.53 ? 23  THR E OG1 1 
ATOM 5384 C CG2 . THR E 3 20  ? 121.184 110.707 167.275 1.00 130.53 ? 23  THR E CG2 1 
ATOM 5385 N N   . CYS E 3 21  ? 124.700 107.660 167.053 1.00 132.63 ? 24  CYS E N   1 
ATOM 5386 C CA  . CYS E 3 21  ? 125.269 106.314 167.002 1.00 132.63 ? 24  CYS E CA  1 
ATOM 5387 C C   . CYS E 3 21  ? 126.366 106.188 168.051 1.00 132.63 ? 24  CYS E C   1 
ATOM 5388 O O   . CYS E 3 21  ? 127.435 106.788 167.930 1.00 132.63 ? 24  CYS E O   1 
ATOM 5389 C CB  . CYS E 3 21  ? 125.798 106.018 165.604 1.00 132.63 ? 24  CYS E CB  1 
ATOM 5390 S SG  . CYS E 3 21  ? 126.857 107.306 164.906 1.00 132.63 ? 24  CYS E SG  1 
ATOM 5391 N N   . ASP E 3 22  ? 126.104 105.400 169.091 1.00 130.67 ? 25  ASP E N   1 
ATOM 5392 C CA  . ASP E 3 22  ? 127.041 105.202 170.188 1.00 130.67 ? 25  ASP E CA  1 
ATOM 5393 C C   . ASP E 3 22  ? 127.378 103.724 170.315 1.00 130.67 ? 25  ASP E C   1 
ATOM 5394 O O   . ASP E 3 22  ? 126.476 102.880 170.363 1.00 130.67 ? 25  ASP E O   1 
ATOM 5395 C CB  . ASP E 3 22  ? 126.467 105.729 171.506 1.00 130.67 ? 25  ASP E CB  1 
ATOM 5396 C CG  . ASP E 3 22  ? 126.168 107.212 171.457 1.00 130.67 ? 25  ASP E CG  1 
ATOM 5397 O OD1 . ASP E 3 22  ? 126.778 107.913 170.623 1.00 130.67 ? 25  ASP E OD1 1 
ATOM 5398 O OD2 . ASP E 3 22  ? 125.325 107.678 172.251 1.00 130.67 ? 25  ASP E OD2 1 
ATOM 5399 N N   . ASN E 3 23  ? 128.678 103.420 170.341 1.00 130.15 ? 26  ASN E N   1 
ATOM 5400 C CA  . ASN E 3 23  ? 129.198 102.078 170.588 1.00 130.15 ? 26  ASN E CA  1 
ATOM 5401 C C   . ASN E 3 23  ? 128.851 101.102 169.470 1.00 130.15 ? 26  ASN E C   1 
ATOM 5402 O O   . ASN E 3 23  ? 129.224 99.927  169.534 1.00 130.15 ? 26  ASN E O   1 
ATOM 5403 C CB  . ASN E 3 23  ? 128.691 101.545 171.932 1.00 130.15 ? 26  ASN E CB  1 
ATOM 5404 C CG  . ASN E 3 23  ? 129.121 102.409 173.100 1.00 130.15 ? 26  ASN E CG  1 
ATOM 5405 O OD1 . ASN E 3 23  ? 128.288 102.916 173.852 1.00 130.15 ? 26  ASN E OD1 1 
ATOM 5406 N ND2 . ASN E 3 23  ? 130.428 102.582 173.257 1.00 130.15 ? 26  ASN E ND2 1 
ATOM 5407 N N   . GLN E 3 24  ? 128.148 101.569 168.444 1.00 127.38 ? 27  GLN E N   1 
ATOM 5408 C CA  . GLN E 3 24  ? 127.824 100.714 167.316 1.00 127.38 ? 27  GLN E CA  1 
ATOM 5409 C C   . GLN E 3 24  ? 129.056 100.507 166.438 1.00 127.38 ? 27  GLN E C   1 
ATOM 5410 O O   . GLN E 3 24  ? 129.990 101.311 166.428 1.00 127.38 ? 27  GLN E O   1 
ATOM 5411 C CB  . GLN E 3 24  ? 126.674 101.307 166.507 1.00 127.38 ? 27  GLN E CB  1 
ATOM 5412 C CG  . GLN E 3 24  ? 125.364 101.367 167.271 1.00 127.38 ? 27  GLN E CG  1 
ATOM 5413 C CD  . GLN E 3 24  ? 124.193 101.740 166.387 1.00 127.38 ? 27  GLN E CD  1 
ATOM 5414 O OE1 . GLN E 3 24  ? 124.341 101.894 165.174 1.00 127.38 ? 27  GLN E OE1 1 
ATOM 5415 N NE2 . GLN E 3 24  ? 123.020 101.887 166.990 1.00 127.38 ? 27  GLN E NE2 1 
ATOM 5416 N N   . LYS E 3 25  ? 129.055 99.394  165.701 1.00 139.90 ? 28  LYS E N   1 
ATOM 5417 C CA  . LYS E 3 25  ? 130.219 99.047  164.891 1.00 139.90 ? 28  LYS E CA  1 
ATOM 5418 C C   . LYS E 3 25  ? 130.471 100.081 163.798 1.00 139.90 ? 28  LYS E C   1 
ATOM 5419 O O   . LYS E 3 25  ? 131.613 100.506 163.591 1.00 139.90 ? 28  LYS E O   1 
ATOM 5420 C CB  . LYS E 3 25  ? 130.041 97.652  164.288 1.00 139.90 ? 28  LYS E CB  1 
ATOM 5421 C CG  . LYS E 3 25  ? 128.726 97.443  163.550 1.00 139.90 ? 28  LYS E CG  1 
ATOM 5422 C CD  . LYS E 3 25  ? 128.698 96.105  162.828 1.00 139.90 ? 28  LYS E CD  1 
ATOM 5423 C CE  . LYS E 3 25  ? 127.424 95.947  162.014 1.00 139.90 ? 28  LYS E CE  1 
ATOM 5424 N NZ  . LYS E 3 25  ? 127.398 94.663  161.262 1.00 139.90 ? 28  LYS E NZ  1 
ATOM 5425 N N   . SER E 3 26  ? 129.422 100.507 163.099 1.00 124.44 ? 29  SER E N   1 
ATOM 5426 C CA  . SER E 3 26  ? 129.576 101.395 161.959 1.00 124.44 ? 29  SER E CA  1 
ATOM 5427 C C   . SER E 3 26  ? 128.516 102.483 162.014 1.00 124.44 ? 29  SER E C   1 
ATOM 5428 O O   . SER E 3 26  ? 127.430 102.298 162.570 1.00 124.44 ? 29  SER E O   1 
ATOM 5429 C CB  . SER E 3 26  ? 129.483 100.634 160.632 1.00 124.44 ? 29  SER E CB  1 
ATOM 5430 O OG  . SER E 3 26  ? 129.624 101.516 159.533 1.00 124.44 ? 29  SER E OG  1 
ATOM 5431 N N   . CYS E 3 27  ? 128.852 103.625 161.423 1.00 128.44 ? 30  CYS E N   1 
ATOM 5432 C CA  . CYS E 3 27  ? 127.969 104.780 161.434 1.00 128.44 ? 30  CYS E CA  1 
ATOM 5433 C C   . CYS E 3 27  ? 128.357 105.717 160.301 1.00 128.44 ? 30  CYS E C   1 
ATOM 5434 O O   . CYS E 3 27  ? 129.450 105.622 159.733 1.00 128.44 ? 30  CYS E O   1 
ATOM 5435 C CB  . CYS E 3 27  ? 128.024 105.512 162.777 1.00 128.44 ? 30  CYS E CB  1 
ATOM 5436 S SG  . CYS E 3 27  ? 126.868 106.888 162.920 1.00 128.44 ? 30  CYS E SG  1 
ATOM 5437 N N   . MET E 3 28  ? 127.440 106.623 159.980 1.00 115.36 ? 31  MET E N   1 
ATOM 5438 C CA  . MET E 3 28  ? 127.669 107.674 159.002 1.00 115.36 ? 31  MET E CA  1 
ATOM 5439 C C   . MET E 3 28  ? 127.849 109.000 159.726 1.00 115.36 ? 31  MET E C   1 
ATOM 5440 O O   . MET E 3 28  ? 127.090 109.323 160.645 1.00 115.36 ? 31  MET E O   1 
ATOM 5441 C CB  . MET E 3 28  ? 126.507 107.768 158.011 1.00 115.36 ? 31  MET E CB  1 
ATOM 5442 C CG  . MET E 3 28  ? 126.251 106.486 157.236 1.00 115.36 ? 31  MET E CG  1 
ATOM 5443 S SD  . MET E 3 28  ? 124.877 106.641 156.081 1.00 115.36 ? 31  MET E SD  1 
ATOM 5444 C CE  . MET E 3 28  ? 124.864 105.008 155.346 1.00 115.36 ? 31  MET E CE  1 
ATOM 5445 N N   . SER E 3 29  ? 128.863 109.762 159.311 1.00 106.50 ? 32  SER E N   1 
ATOM 5446 C CA  . SER E 3 29  ? 129.175 111.012 159.996 1.00 106.50 ? 32  SER E CA  1 
ATOM 5447 C C   . SER E 3 29  ? 128.024 112.005 159.918 1.00 106.50 ? 32  SER E C   1 
ATOM 5448 O O   . SER E 3 29  ? 127.889 112.864 160.796 1.00 106.50 ? 32  SER E O   1 
ATOM 5449 C CB  . SER E 3 29  ? 130.446 111.627 159.412 1.00 106.50 ? 32  SER E CB  1 
ATOM 5450 O OG  . SER E 3 29  ? 130.826 112.786 160.132 1.00 106.50 ? 32  SER E OG  1 
ATOM 5451 N N   . ASN E 3 30  ? 127.191 111.905 158.881 1.00 90.78  ? 33  ASN E N   1 
ATOM 5452 C CA  . ASN E 3 30  ? 126.042 112.793 158.701 1.00 90.78  ? 33  ASN E CA  1 
ATOM 5453 C C   . ASN E 3 30  ? 126.474 114.255 158.694 1.00 90.78  ? 33  ASN E C   1 
ATOM 5454 O O   . ASN E 3 30  ? 125.764 115.136 159.183 1.00 90.78  ? 33  ASN E O   1 
ATOM 5455 C CB  . ASN E 3 30  ? 124.975 112.546 159.769 1.00 90.78  ? 33  ASN E CB  1 
ATOM 5456 C CG  . ASN E 3 30  ? 124.472 111.119 159.769 1.00 90.78  ? 33  ASN E CG  1 
ATOM 5457 O OD1 . ASN E 3 30  ? 124.472 110.448 158.738 1.00 90.78  ? 33  ASN E OD1 1 
ATOM 5458 N ND2 . ASN E 3 30  ? 124.038 110.646 160.931 1.00 90.78  ? 33  ASN E ND2 1 
ATOM 5459 N N   . CYS E 3 31  ? 127.650 114.515 158.136 1.00 88.03  ? 34  CYS E N   1 
ATOM 5460 C CA  . CYS E 3 31  ? 128.199 115.858 158.037 1.00 88.03  ? 34  CYS E CA  1 
ATOM 5461 C C   . CYS E 3 31  ? 127.877 116.413 156.660 1.00 88.03  ? 34  CYS E C   1 
ATOM 5462 O O   . CYS E 3 31  ? 128.275 115.834 155.644 1.00 88.03  ? 34  CYS E O   1 
ATOM 5463 C CB  . CYS E 3 31  ? 129.706 115.852 158.277 1.00 88.03  ? 34  CYS E CB  1 
ATOM 5464 S SG  . CYS E 3 31  ? 130.493 117.430 157.941 1.00 88.03  ? 34  CYS E SG  1 
ATOM 5465 N N   . SER E 3 32  ? 127.167 117.532 156.627 1.00 76.31  ? 35  SER E N   1 
ATOM 5466 C CA  . SER E 3 32  ? 126.715 118.100 155.367 1.00 76.31  ? 35  SER E CA  1 
ATOM 5467 C C   . SER E 3 32  ? 127.809 118.848 154.619 1.00 76.31  ? 35  SER E C   1 
ATOM 5468 O O   . SER E 3 32  ? 127.569 119.287 153.491 1.00 76.31  ? 35  SER E O   1 
ATOM 5469 C CB  . SER E 3 32  ? 125.526 119.032 155.613 1.00 76.31  ? 35  SER E CB  1 
ATOM 5470 O OG  . SER E 3 32  ? 125.844 120.022 156.574 1.00 76.31  ? 35  SER E OG  1 
ATOM 5471 N N   . ILE E 3 33  ? 128.991 119.002 155.202 1.00 52.33  ? 36  ILE E N   1 
ATOM 5472 C CA  . ILE E 3 33  ? 130.065 119.783 154.600 1.00 52.33  ? 36  ILE E CA  1 
ATOM 5473 C C   . ILE E 3 33  ? 131.152 118.826 154.131 1.00 52.33  ? 36  ILE E C   1 
ATOM 5474 O O   . ILE E 3 33  ? 131.767 118.123 154.938 1.00 52.33  ? 36  ILE E O   1 
ATOM 5475 C CB  . ILE E 3 33  ? 130.630 120.820 155.579 1.00 52.33  ? 36  ILE E CB  1 
ATOM 5476 C CG1 . ILE E 3 33  ? 129.632 121.953 155.808 1.00 52.33  ? 36  ILE E CG1 1 
ATOM 5477 C CG2 . ILE E 3 33  ? 131.933 121.380 155.058 1.00 52.33  ? 36  ILE E CG2 1 
ATOM 5478 C CD1 . ILE E 3 33  ? 128.639 121.689 156.910 1.00 52.33  ? 36  ILE E CD1 1 
ATOM 5479 N N   . THR E 3 34  ? 131.397 118.798 152.825 1.00 43.42  ? 37  THR E N   1 
ATOM 5480 C CA  . THR E 3 34  ? 132.537 118.102 152.245 1.00 43.42  ? 37  THR E CA  1 
ATOM 5481 C C   . THR E 3 34  ? 133.514 119.152 151.744 1.00 43.42  ? 37  THR E C   1 
ATOM 5482 O O   . THR E 3 34  ? 133.166 119.961 150.879 1.00 43.42  ? 37  THR E O   1 
ATOM 5483 C CB  . THR E 3 34  ? 132.111 117.183 151.105 1.00 43.42  ? 37  THR E CB  1 
ATOM 5484 O OG1 . THR E 3 34  ? 131.363 116.083 151.631 1.00 43.42  ? 37  THR E OG1 1 
ATOM 5485 C CG2 . THR E 3 34  ? 133.328 116.658 150.375 1.00 43.42  ? 37  THR E CG2 1 
ATOM 5486 N N   . SER E 3 35  ? 134.730 119.134 152.276 1.00 48.88  ? 38  SER E N   1 
ATOM 5487 C CA  . SER E 3 35  ? 135.691 120.199 152.068 1.00 48.88  ? 38  SER E CA  1 
ATOM 5488 C C   . SER E 3 35  ? 136.960 119.659 151.432 1.00 48.88  ? 38  SER E C   1 
ATOM 5489 O O   . SER E 3 35  ? 137.408 118.550 151.741 1.00 48.88  ? 38  SER E O   1 
ATOM 5490 C CB  . SER E 3 35  ? 136.041 120.879 153.389 1.00 48.88  ? 38  SER E CB  1 
ATOM 5491 O OG  . SER E 3 35  ? 137.012 121.893 153.199 1.00 48.88  ? 38  SER E OG  1 
ATOM 5492 N N   . ILE E 3 36  ? 137.532 120.455 150.538 1.00 44.41  ? 39  ILE E N   1 
ATOM 5493 C CA  . ILE E 3 36  ? 138.876 120.212 150.038 1.00 44.41  ? 39  ILE E CA  1 
ATOM 5494 C C   . ILE E 3 36  ? 139.845 120.795 151.056 1.00 44.41  ? 39  ILE E C   1 
ATOM 5495 O O   . ILE E 3 36  ? 139.720 121.959 151.451 1.00 44.41  ? 39  ILE E O   1 
ATOM 5496 C CB  . ILE E 3 36  ? 139.078 120.818 148.641 1.00 44.41  ? 39  ILE E CB  1 
ATOM 5497 C CG1 . ILE E 3 36  ? 138.780 122.311 148.626 1.00 44.41  ? 39  ILE E CG1 1 
ATOM 5498 C CG2 . ILE E 3 36  ? 138.161 120.157 147.648 1.00 44.41  ? 39  ILE E CG2 1 
ATOM 5499 C CD1 . ILE E 3 36  ? 138.691 122.885 147.234 1.00 44.41  ? 39  ILE E CD1 1 
ATOM 5500 N N   . CYS E 3 37  ? 140.786 119.976 151.515 1.00 68.27  ? 40  CYS E N   1 
ATOM 5501 C CA  . CYS E 3 37  ? 141.644 120.385 152.616 1.00 68.27  ? 40  CYS E CA  1 
ATOM 5502 C C   . CYS E 3 37  ? 142.512 121.565 152.207 1.00 68.27  ? 40  CYS E C   1 
ATOM 5503 O O   . CYS E 3 37  ? 142.890 121.706 151.042 1.00 68.27  ? 40  CYS E O   1 
ATOM 5504 C CB  . CYS E 3 37  ? 142.515 119.219 153.071 1.00 68.27  ? 40  CYS E CB  1 
ATOM 5505 S SG  . CYS E 3 37  ? 141.613 117.789 153.704 1.00 68.27  ? 40  CYS E SG  1 
ATOM 5506 N N   . GLU E 3 38  ? 142.824 122.421 153.182 1.00 99.68  ? 41  GLU E N   1 
ATOM 5507 C CA  . GLU E 3 38  ? 143.550 123.653 152.892 1.00 99.68  ? 41  GLU E CA  1 
ATOM 5508 C C   . GLU E 3 38  ? 144.926 123.378 152.302 1.00 99.68  ? 41  GLU E C   1 
ATOM 5509 O O   . GLU E 3 38  ? 145.346 124.063 151.363 1.00 99.68  ? 41  GLU E O   1 
ATOM 5510 C CB  . GLU E 3 38  ? 143.674 124.497 154.160 1.00 99.68  ? 41  GLU E CB  1 
ATOM 5511 C CG  . GLU E 3 38  ? 144.524 125.745 153.992 1.00 99.68  ? 41  GLU E CG  1 
ATOM 5512 C CD  . GLU E 3 38  ? 143.936 126.726 152.998 1.00 99.68  ? 41  GLU E CD  1 
ATOM 5513 O OE1 . GLU E 3 38  ? 142.750 127.084 153.147 1.00 99.68  ? 41  GLU E OE1 1 
ATOM 5514 O OE2 . GLU E 3 38  ? 144.657 127.135 152.064 1.00 99.68  ? 41  GLU E OE2 1 
ATOM 5515 N N   . LYS E 3 39  ? 145.637 122.387 152.826 1.00 95.11  ? 42  LYS E N   1 
ATOM 5516 C CA  . LYS E 3 39  ? 146.970 122.061 152.351 1.00 95.11  ? 42  LYS E CA  1 
ATOM 5517 C C   . LYS E 3 39  ? 146.986 120.642 151.807 1.00 95.11  ? 42  LYS E C   1 
ATOM 5518 O O   . LYS E 3 39  ? 146.326 119.755 152.357 1.00 95.11  ? 42  LYS E O   1 
ATOM 5519 C CB  . LYS E 3 39  ? 148.005 122.196 153.475 1.00 95.11  ? 42  LYS E CB  1 
ATOM 5520 C CG  . LYS E 3 39  ? 147.940 123.521 154.214 1.00 95.11  ? 42  LYS E CG  1 
ATOM 5521 C CD  . LYS E 3 39  ? 148.923 123.557 155.371 1.00 95.11  ? 42  LYS E CD  1 
ATOM 5522 C CE  . LYS E 3 39  ? 148.750 124.816 156.200 1.00 95.11  ? 42  LYS E CE  1 
ATOM 5523 N NZ  . LYS E 3 39  ? 147.378 124.917 156.770 1.00 95.11  ? 42  LYS E NZ  1 
ATOM 5524 N N   . PRO E 3 40  ? 147.734 120.399 150.728 1.00 91.14  ? 43  PRO E N   1 
ATOM 5525 C CA  . PRO E 3 40  ? 147.723 119.058 150.119 1.00 91.14  ? 43  PRO E CA  1 
ATOM 5526 C C   . PRO E 3 40  ? 148.254 117.968 151.031 1.00 91.14  ? 43  PRO E C   1 
ATOM 5527 O O   . PRO E 3 40  ? 147.935 116.791 150.826 1.00 91.14  ? 43  PRO E O   1 
ATOM 5528 C CB  . PRO E 3 40  ? 148.606 119.236 148.876 1.00 91.14  ? 43  PRO E CB  1 
ATOM 5529 C CG  . PRO E 3 40  ? 149.479 120.399 149.198 1.00 91.14  ? 43  PRO E CG  1 
ATOM 5530 C CD  . PRO E 3 40  ? 148.638 121.322 150.025 1.00 91.14  ? 43  PRO E CD  1 
ATOM 5531 N N   . GLN E 3 41  ? 149.056 118.324 152.032 1.00 89.92  ? 44  GLN E N   1 
ATOM 5532 C CA  . GLN E 3 41  ? 149.630 117.342 152.942 1.00 89.92  ? 44  GLN E CA  1 
ATOM 5533 C C   . GLN E 3 41  ? 148.623 116.793 153.944 1.00 89.92  ? 44  GLN E C   1 
ATOM 5534 O O   . GLN E 3 41  ? 148.949 115.842 154.661 1.00 89.92  ? 44  GLN E O   1 
ATOM 5535 C CB  . GLN E 3 41  ? 150.807 117.967 153.687 1.00 89.92  ? 44  GLN E CB  1 
ATOM 5536 C CG  . GLN E 3 41  ? 150.457 119.276 154.375 1.00 89.92  ? 44  GLN E CG  1 
ATOM 5537 C CD  . GLN E 3 41  ? 151.671 119.986 154.940 1.00 89.92  ? 44  GLN E CD  1 
ATOM 5538 O OE1 . GLN E 3 41  ? 152.808 119.579 154.703 1.00 89.92  ? 44  GLN E OE1 1 
ATOM 5539 N NE2 . GLN E 3 41  ? 151.434 121.054 155.692 1.00 89.92  ? 44  GLN E NE2 1 
ATOM 5540 N N   . GLU E 3 42  ? 147.422 117.360 154.013 1.00 82.05  ? 45  GLU E N   1 
ATOM 5541 C CA  . GLU E 3 42  ? 146.478 117.033 155.070 1.00 82.05  ? 45  GLU E CA  1 
ATOM 5542 C C   . GLU E 3 42  ? 145.659 115.793 154.724 1.00 82.05  ? 45  GLU E C   1 
ATOM 5543 O O   . GLU E 3 42  ? 145.505 115.418 153.560 1.00 82.05  ? 45  GLU E O   1 
ATOM 5544 C CB  . GLU E 3 42  ? 145.555 118.221 155.336 1.00 82.05  ? 45  GLU E CB  1 
ATOM 5545 C CG  . GLU E 3 42  ? 146.294 119.454 155.826 1.00 82.05  ? 45  GLU E CG  1 
ATOM 5546 C CD  . GLU E 3 42  ? 145.500 120.725 155.644 1.00 82.05  ? 45  GLU E CD  1 
ATOM 5547 O OE1 . GLU E 3 42  ? 144.861 120.879 154.584 1.00 82.05  ? 45  GLU E OE1 1 
ATOM 5548 O OE2 . GLU E 3 42  ? 145.513 121.572 156.561 1.00 82.05  ? 45  GLU E OE2 1 
ATOM 5549 N N   . VAL E 3 43  ? 145.136 115.149 155.768 1.00 77.47  ? 46  VAL E N   1 
ATOM 5550 C CA  . VAL E 3 43  ? 144.322 113.949 155.647 1.00 77.47  ? 46  VAL E CA  1 
ATOM 5551 C C   . VAL E 3 43  ? 143.107 114.094 156.552 1.00 77.47  ? 46  VAL E C   1 
ATOM 5552 O O   . VAL E 3 43  ? 143.068 114.938 157.451 1.00 77.47  ? 46  VAL E O   1 
ATOM 5553 C CB  . VAL E 3 43  ? 145.106 112.670 156.003 1.00 77.47  ? 46  VAL E CB  1 
ATOM 5554 C CG1 . VAL E 3 43  ? 146.273 112.475 155.051 1.00 77.47  ? 46  VAL E CG1 1 
ATOM 5555 C CG2 . VAL E 3 43  ? 145.587 112.731 157.440 1.00 77.47  ? 46  VAL E CG2 1 
ATOM 5556 N N   . CYS E 3 44  ? 142.103 113.258 156.301 1.00 74.10  ? 47  CYS E N   1 
ATOM 5557 C CA  . CYS E 3 44  ? 140.861 113.339 157.050 1.00 74.10  ? 47  CYS E CA  1 
ATOM 5558 C C   . CYS E 3 44  ? 141.040 112.733 158.433 1.00 74.10  ? 47  CYS E C   1 
ATOM 5559 O O   . CYS E 3 44  ? 141.714 111.713 158.595 1.00 74.10  ? 47  CYS E O   1 
ATOM 5560 C CB  . CYS E 3 44  ? 139.736 112.616 156.313 1.00 74.10  ? 47  CYS E CB  1 
ATOM 5561 S SG  . CYS E 3 44  ? 139.657 112.931 154.540 1.00 74.10  ? 47  CYS E SG  1 
ATOM 5562 N N   . VAL E 3 45  ? 140.425 113.365 159.429 1.00 86.53  ? 48  VAL E N   1 
ATOM 5563 C CA  . VAL E 3 45  ? 140.494 112.931 160.817 1.00 86.53  ? 48  VAL E CA  1 
ATOM 5564 C C   . VAL E 3 45  ? 139.087 112.953 161.392 1.00 86.53  ? 48  VAL E C   1 
ATOM 5565 O O   . VAL E 3 45  ? 138.348 113.921 161.191 1.00 86.53  ? 48  VAL E O   1 
ATOM 5566 C CB  . VAL E 3 45  ? 141.427 113.835 161.644 1.00 86.53  ? 48  VAL E CB  1 
ATOM 5567 C CG1 . VAL E 3 45  ? 141.290 113.537 163.125 1.00 86.53  ? 48  VAL E CG1 1 
ATOM 5568 C CG2 . VAL E 3 45  ? 142.864 113.668 161.190 1.00 86.53  ? 48  VAL E CG2 1 
ATOM 5569 N N   . ALA E 3 46  ? 138.719 111.890 162.103 1.00 92.90  ? 49  ALA E N   1 
ATOM 5570 C CA  . ALA E 3 46  ? 137.439 111.807 162.792 1.00 92.90  ? 49  ALA E CA  1 
ATOM 5571 C C   . ALA E 3 46  ? 137.687 111.508 164.262 1.00 92.90  ? 49  ALA E C   1 
ATOM 5572 O O   . ALA E 3 46  ? 138.521 110.659 164.595 1.00 92.90  ? 49  ALA E O   1 
ATOM 5573 C CB  . ALA E 3 46  ? 136.542 110.734 162.172 1.00 92.90  ? 49  ALA E CB  1 
ATOM 5574 N N   . VAL E 3 47  ? 136.968 112.210 165.134 1.00 109.56 ? 50  VAL E N   1 
ATOM 5575 C CA  . VAL E 3 47  ? 137.120 112.097 166.578 1.00 109.56 ? 50  VAL E CA  1 
ATOM 5576 C C   . VAL E 3 47  ? 135.742 111.919 167.200 1.00 109.56 ? 50  VAL E C   1 
ATOM 5577 O O   . VAL E 3 47  ? 134.899 112.818 167.114 1.00 109.56 ? 50  VAL E O   1 
ATOM 5578 C CB  . VAL E 3 47  ? 137.819 113.335 167.168 1.00 109.56 ? 50  VAL E CB  1 
ATOM 5579 C CG1 . VAL E 3 47  ? 137.713 113.334 168.676 1.00 109.56 ? 50  VAL E CG1 1 
ATOM 5580 C CG2 . VAL E 3 47  ? 139.271 113.381 166.731 1.00 109.56 ? 50  VAL E CG2 1 
ATOM 5581 N N   . TRP E 3 48  ? 135.517 110.776 167.838 1.00 133.71 ? 51  TRP E N   1 
ATOM 5582 C CA  . TRP E 3 48  ? 134.245 110.470 168.478 1.00 133.71 ? 51  TRP E CA  1 
ATOM 5583 C C   . TRP E 3 48  ? 134.434 110.526 169.986 1.00 133.71 ? 51  TRP E C   1 
ATOM 5584 O O   . TRP E 3 48  ? 135.215 109.750 170.548 1.00 133.71 ? 51  TRP E O   1 
ATOM 5585 C CB  . TRP E 3 48  ? 133.731 109.097 168.046 1.00 133.71 ? 51  TRP E CB  1 
ATOM 5586 C CG  . TRP E 3 48  ? 132.405 108.746 168.629 1.00 133.71 ? 51  TRP E CG  1 
ATOM 5587 C CD1 . TRP E 3 48  ? 131.189 109.211 168.231 1.00 133.71 ? 51  TRP E CD1 1 
ATOM 5588 C CD2 . TRP E 3 48  ? 132.156 107.846 169.715 1.00 133.71 ? 51  TRP E CD2 1 
ATOM 5589 N NE1 . TRP E 3 48  ? 130.196 108.661 169.002 1.00 133.71 ? 51  TRP E NE1 1 
ATOM 5590 C CE2 . TRP E 3 48  ? 130.763 107.819 169.921 1.00 133.71 ? 51  TRP E CE2 1 
ATOM 5591 C CE3 . TRP E 3 48  ? 132.975 107.063 170.534 1.00 133.71 ? 51  TRP E CE3 1 
ATOM 5592 C CZ2 . TRP E 3 48  ? 130.171 107.039 170.913 1.00 133.71 ? 51  TRP E CZ2 1 
ATOM 5593 C CZ3 . TRP E 3 48  ? 132.385 106.289 171.518 1.00 133.71 ? 51  TRP E CZ3 1 
ATOM 5594 C CH2 . TRP E 3 48  ? 130.997 106.282 171.697 1.00 133.71 ? 51  TRP E CH2 1 
ATOM 5595 N N   . ARG E 3 49  ? 133.720 111.439 170.638 1.00 139.93 ? 52  ARG E N   1 
ATOM 5596 C CA  . ARG E 3 49  ? 133.818 111.637 172.077 1.00 139.93 ? 52  ARG E CA  1 
ATOM 5597 C C   . ARG E 3 49  ? 132.483 111.267 172.705 1.00 139.93 ? 52  ARG E C   1 
ATOM 5598 O O   . ARG E 3 49  ? 131.428 111.696 172.227 1.00 139.93 ? 52  ARG E O   1 
ATOM 5599 C CB  . ARG E 3 49  ? 134.203 113.081 172.400 1.00 139.93 ? 52  ARG E CB  1 
ATOM 5600 C CG  . ARG E 3 49  ? 134.197 113.418 173.883 1.00 139.93 ? 52  ARG E CG  1 
ATOM 5601 C CD  . ARG E 3 49  ? 135.223 114.494 174.223 1.00 139.93 ? 52  ARG E CD  1 
ATOM 5602 N NE  . ARG E 3 49  ? 135.216 115.603 173.275 1.00 139.93 ? 52  ARG E NE  1 
ATOM 5603 C CZ  . ARG E 3 49  ? 136.125 115.783 172.327 1.00 139.93 ? 52  ARG E CZ  1 
ATOM 5604 N NH1 . ARG E 3 49  ? 137.133 114.941 172.168 1.00 139.93 ? 52  ARG E NH1 1 
ATOM 5605 N NH2 . ARG E 3 49  ? 136.021 116.833 171.518 1.00 139.93 ? 52  ARG E NH2 1 
ATOM 5606 N N   . LYS E 3 50  ? 132.532 110.460 173.760 1.00 150.26 ? 53  LYS E N   1 
ATOM 5607 C CA  . LYS E 3 50  ? 131.347 110.013 174.478 1.00 150.26 ? 53  LYS E CA  1 
ATOM 5608 C C   . LYS E 3 50  ? 131.449 110.439 175.935 1.00 150.26 ? 53  LYS E C   1 
ATOM 5609 O O   . LYS E 3 50  ? 132.443 110.137 176.608 1.00 150.26 ? 53  LYS E O   1 
ATOM 5610 C CB  . LYS E 3 50  ? 131.187 108.495 174.381 1.00 150.26 ? 53  LYS E CB  1 
ATOM 5611 C CG  . LYS E 3 50  ? 130.056 107.933 175.226 1.00 150.26 ? 53  LYS E CG  1 
ATOM 5612 C CD  . LYS E 3 50  ? 129.974 106.420 175.108 1.00 150.26 ? 53  LYS E CD  1 
ATOM 5613 C CE  . LYS E 3 50  ? 128.824 105.864 175.931 1.00 150.26 ? 53  LYS E CE  1 
ATOM 5614 N NZ  . LYS E 3 50  ? 127.512 106.412 175.490 1.00 150.26 ? 53  LYS E NZ  1 
ATOM 5615 N N   . ASN E 3 51  ? 130.420 111.133 176.413 1.00 167.67 ? 54  ASN E N   1 
ATOM 5616 C CA  . ASN E 3 51  ? 130.333 111.599 177.788 1.00 167.67 ? 54  ASN E CA  1 
ATOM 5617 C C   . ASN E 3 51  ? 128.996 111.166 178.372 1.00 167.67 ? 54  ASN E C   1 
ATOM 5618 O O   . ASN E 3 51  ? 128.064 110.804 177.648 1.00 167.67 ? 54  ASN E O   1 
ATOM 5619 C CB  . ASN E 3 51  ? 130.477 113.126 177.881 1.00 167.67 ? 54  ASN E CB  1 
ATOM 5620 C CG  . ASN E 3 51  ? 131.643 113.657 177.071 1.00 167.67 ? 54  ASN E CG  1 
ATOM 5621 O OD1 . ASN E 3 51  ? 132.675 113.001 176.940 1.00 167.67 ? 54  ASN E OD1 1 
ATOM 5622 N ND2 . ASN E 3 51  ? 131.483 114.854 176.521 1.00 167.67 ? 54  ASN E ND2 1 
ATOM 5623 N N   . ASP E 3 52  ? 128.906 111.204 179.703 1.00 180.10 ? 55  ASP E N   1 
ATOM 5624 C CA  . ASP E 3 52  ? 127.644 110.900 180.366 1.00 180.10 ? 55  ASP E CA  1 
ATOM 5625 C C   . ASP E 3 52  ? 126.578 111.949 180.080 1.00 180.10 ? 55  ASP E C   1 
ATOM 5626 O O   . ASP E 3 52  ? 125.385 111.659 180.222 1.00 180.10 ? 55  ASP E O   1 
ATOM 5627 C CB  . ASP E 3 52  ? 127.862 110.769 181.875 1.00 180.10 ? 55  ASP E CB  1 
ATOM 5628 C CG  . ASP E 3 52  ? 126.617 110.304 182.606 1.00 180.10 ? 55  ASP E CG  1 
ATOM 5629 O OD1 . ASP E 3 52  ? 126.228 109.130 182.435 1.00 180.10 ? 55  ASP E OD1 1 
ATOM 5630 O OD2 . ASP E 3 52  ? 126.027 111.114 183.352 1.00 180.10 ? 55  ASP E OD2 1 
ATOM 5631 N N   . GLU E 3 53  ? 126.977 113.154 179.671 1.00 179.98 ? 56  GLU E N   1 
ATOM 5632 C CA  . GLU E 3 53  ? 126.043 114.240 179.391 1.00 179.98 ? 56  GLU E CA  1 
ATOM 5633 C C   . GLU E 3 53  ? 125.643 114.283 177.919 1.00 179.98 ? 56  GLU E C   1 
ATOM 5634 O O   . GLU E 3 53  ? 124.452 114.309 177.597 1.00 179.98 ? 56  GLU E O   1 
ATOM 5635 C CB  . GLU E 3 53  ? 126.651 115.584 179.819 1.00 179.98 ? 56  GLU E CB  1 
ATOM 5636 C CG  . GLU E 3 53  ? 126.920 115.715 181.314 1.00 179.98 ? 56  GLU E CG  1 
ATOM 5637 C CD  . GLU E 3 53  ? 128.197 115.020 181.750 1.00 179.98 ? 56  GLU E CD  1 
ATOM 5638 O OE1 . GLU E 3 53  ? 128.957 114.561 180.871 1.00 179.98 ? 56  GLU E OE1 1 
ATOM 5639 O OE2 . GLU E 3 53  ? 128.440 114.933 182.972 1.00 179.98 ? 56  GLU E OE2 1 
ATOM 5640 N N   . ASN E 3 54  ? 126.622 114.293 177.017 1.00 166.41 ? 57  ASN E N   1 
ATOM 5641 C CA  . ASN E 3 54  ? 126.345 114.390 175.592 1.00 166.41 ? 57  ASN E CA  1 
ATOM 5642 C C   . ASN E 3 54  ? 127.424 113.655 174.811 1.00 166.41 ? 57  ASN E C   1 
ATOM 5643 O O   . ASN E 3 54  ? 128.527 113.424 175.314 1.00 166.41 ? 57  ASN E O   1 
ATOM 5644 C CB  . ASN E 3 54  ? 126.264 115.853 175.136 1.00 166.41 ? 57  ASN E CB  1 
ATOM 5645 C CG  . ASN E 3 54  ? 127.549 116.616 175.397 1.00 166.41 ? 57  ASN E CG  1 
ATOM 5646 O OD1 . ASN E 3 54  ? 128.441 116.661 174.549 1.00 166.41 ? 57  ASN E OD1 1 
ATOM 5647 N ND2 . ASN E 3 54  ? 127.648 117.222 176.574 1.00 166.41 ? 57  ASN E ND2 1 
ATOM 5648 N N   . ILE E 3 55  ? 127.092 113.291 173.574 1.00 144.68 ? 58  ILE E N   1 
ATOM 5649 C CA  . ILE E 3 55  ? 128.008 112.600 172.673 1.00 144.68 ? 58  ILE E CA  1 
ATOM 5650 C C   . ILE E 3 55  ? 128.294 113.521 171.497 1.00 144.68 ? 58  ILE E C   1 
ATOM 5651 O O   . ILE E 3 55  ? 127.385 114.191 170.992 1.00 144.68 ? 58  ILE E O   1 
ATOM 5652 C CB  . ILE E 3 55  ? 127.421 111.261 172.195 1.00 144.68 ? 58  ILE E CB  1 
ATOM 5653 C CG1 . ILE E 3 55  ? 126.527 110.647 173.274 1.00 144.68 ? 58  ILE E CG1 1 
ATOM 5654 C CG2 . ILE E 3 55  ? 128.537 110.299 171.840 1.00 144.68 ? 58  ILE E CG2 1 
ATOM 5655 C CD1 . ILE E 3 55  ? 127.277 110.154 174.494 1.00 144.68 ? 58  ILE E CD1 1 
ATOM 5656 N N   . THR E 3 56  ? 129.553 113.567 171.063 1.00 126.12 ? 59  THR E N   1 
ATOM 5657 C CA  . THR E 3 56  ? 129.978 114.480 170.013 1.00 126.12 ? 59  THR E CA  1 
ATOM 5658 C C   . THR E 3 56  ? 130.828 113.756 168.977 1.00 126.12 ? 59  THR E C   1 
ATOM 5659 O O   . THR E 3 56  ? 131.515 112.777 169.280 1.00 126.12 ? 59  THR E O   1 
ATOM 5660 C CB  . THR E 3 56  ? 130.772 115.658 170.589 1.00 126.12 ? 59  THR E CB  1 
ATOM 5661 O OG1 . THR E 3 56  ? 131.852 115.161 171.389 1.00 126.12 ? 59  THR E OG1 1 
ATOM 5662 C CG2 . THR E 3 56  ? 129.874 116.542 171.446 1.00 126.12 ? 59  THR E CG2 1 
ATOM 5663 N N   . LEU E 3 57  ? 130.772 114.258 167.744 1.00 103.19 ? 60  LEU E N   1 
ATOM 5664 C CA  . LEU E 3 57  ? 131.576 113.752 166.638 1.00 103.19 ? 60  LEU E CA  1 
ATOM 5665 C C   . LEU E 3 57  ? 132.193 114.940 165.917 1.00 103.19 ? 60  LEU E C   1 
ATOM 5666 O O   . LEU E 3 57  ? 131.481 115.875 165.539 1.00 103.19 ? 60  LEU E O   1 
ATOM 5667 C CB  . LEU E 3 57  ? 130.730 112.916 165.674 1.00 103.19 ? 60  LEU E CB  1 
ATOM 5668 C CG  . LEU E 3 57  ? 131.421 112.373 164.421 1.00 103.19 ? 60  LEU E CG  1 
ATOM 5669 C CD1 . LEU E 3 57  ? 132.534 111.411 164.802 1.00 103.19 ? 60  LEU E CD1 1 
ATOM 5670 C CD2 . LEU E 3 57  ? 130.428 111.705 163.488 1.00 103.19 ? 60  LEU E CD2 1 
ATOM 5671 N N   . GLU E 3 58  ? 133.507 114.903 165.730 1.00 97.16  ? 61  GLU E N   1 
ATOM 5672 C CA  . GLU E 3 58  ? 134.247 115.973 165.081 1.00 97.16  ? 61  GLU E CA  1 
ATOM 5673 C C   . GLU E 3 58  ? 134.971 115.416 163.866 1.00 97.16  ? 61  GLU E C   1 
ATOM 5674 O O   . GLU E 3 58  ? 135.434 114.273 163.880 1.00 97.16  ? 61  GLU E O   1 
ATOM 5675 C CB  . GLU E 3 58  ? 135.252 116.616 166.042 1.00 97.16  ? 61  GLU E CB  1 
ATOM 5676 C CG  . GLU E 3 58  ? 136.013 117.792 165.454 1.00 97.16  ? 61  GLU E CG  1 
ATOM 5677 C CD  . GLU E 3 58  ? 136.965 118.426 166.444 1.00 97.16  ? 61  GLU E CD  1 
ATOM 5678 O OE1 . GLU E 3 58  ? 137.094 117.899 167.567 1.00 97.16  ? 61  GLU E OE1 1 
ATOM 5679 O OE2 . GLU E 3 58  ? 137.585 119.454 166.102 1.00 97.16  ? 61  GLU E OE2 1 
ATOM 5680 N N   . THR E 3 59  ? 135.057 116.222 162.813 1.00 71.07  ? 62  THR E N   1 
ATOM 5681 C CA  . THR E 3 59  ? 135.721 115.830 161.580 1.00 71.07  ? 62  THR E CA  1 
ATOM 5682 C C   . THR E 3 59  ? 136.560 117.002 161.102 1.00 71.07  ? 62  THR E C   1 
ATOM 5683 O O   . THR E 3 59  ? 136.087 118.140 161.115 1.00 71.07  ? 62  THR E O   1 
ATOM 5684 C CB  . THR E 3 59  ? 134.698 115.433 160.516 1.00 71.07  ? 62  THR E CB  1 
ATOM 5685 O OG1 . THR E 3 59  ? 133.738 116.485 160.370 1.00 71.07  ? 62  THR E OG1 1 
ATOM 5686 C CG2 . THR E 3 59  ? 133.977 114.159 160.912 1.00 71.07  ? 62  THR E CG2 1 
ATOM 5687 N N   . VAL E 3 60  ? 137.797 116.734 160.686 1.00 66.91  ? 63  VAL E N   1 
ATOM 5688 C CA  . VAL E 3 60  ? 138.718 117.810 160.338 1.00 66.91  ? 63  VAL E CA  1 
ATOM 5689 C C   . VAL E 3 60  ? 139.639 117.374 159.209 1.00 66.91  ? 63  VAL E C   1 
ATOM 5690 O O   . VAL E 3 60  ? 139.883 116.184 158.999 1.00 66.91  ? 63  VAL E O   1 
ATOM 5691 C CB  . VAL E 3 60  ? 139.553 118.264 161.559 1.00 66.91  ? 63  VAL E CB  1 
ATOM 5692 C CG1 . VAL E 3 60  ? 138.752 119.195 162.452 1.00 66.91  ? 63  VAL E CG1 1 
ATOM 5693 C CG2 . VAL E 3 60  ? 140.026 117.062 162.344 1.00 66.91  ? 63  VAL E CG2 1 
ATOM 5694 N N   . CYS E 3 61  ? 140.134 118.361 158.467 1.00 61.29  ? 64  CYS E N   1 
ATOM 5695 C CA  . CYS E 3 61  ? 141.302 118.197 157.610 1.00 61.29  ? 64  CYS E CA  1 
ATOM 5696 C C   . CYS E 3 61  ? 142.530 118.528 158.445 1.00 61.29  ? 64  CYS E C   1 
ATOM 5697 O O   . CYS E 3 61  ? 142.782 119.700 158.740 1.00 61.29  ? 64  CYS E O   1 
ATOM 5698 C CB  . CYS E 3 61  ? 141.222 119.120 156.396 1.00 61.29  ? 64  CYS E CB  1 
ATOM 5699 S SG  . CYS E 3 61  ? 140.244 118.558 154.991 1.00 61.29  ? 64  CYS E SG  1 
ATOM 5700 N N   . HIS E 3 62  ? 143.298 117.516 158.836 1.00 93.28  ? 65  HIS E N   1 
ATOM 5701 C CA  . HIS E 3 62  ? 144.402 117.734 159.756 1.00 93.28  ? 65  HIS E CA  1 
ATOM 5702 C C   . HIS E 3 62  ? 145.690 117.177 159.175 1.00 93.28  ? 65  HIS E C   1 
ATOM 5703 O O   . HIS E 3 62  ? 145.677 116.232 158.384 1.00 93.28  ? 65  HIS E O   1 
ATOM 5704 C CB  . HIS E 3 62  ? 144.129 117.093 161.120 1.00 93.28  ? 65  HIS E CB  1 
ATOM 5705 C CG  . HIS E 3 62  ? 144.879 117.733 162.245 1.00 93.28  ? 65  HIS E CG  1 
ATOM 5706 N ND1 . HIS E 3 62  ? 145.772 117.042 163.034 1.00 93.28  ? 65  HIS E ND1 1 
ATOM 5707 C CD2 . HIS E 3 62  ? 144.871 119.005 162.711 1.00 93.28  ? 65  HIS E CD2 1 
ATOM 5708 C CE1 . HIS E 3 62  ? 146.279 117.858 163.940 1.00 93.28  ? 65  HIS E CE1 1 
ATOM 5709 N NE2 . HIS E 3 62  ? 145.749 119.055 163.766 1.00 93.28  ? 65  HIS E NE2 1 
ATOM 5710 N N   . ASP E 3 63  ? 146.805 117.819 159.532 1.00 102.79 ? 66  ASP E N   1 
ATOM 5711 C CA  . ASP E 3 63  ? 148.127 117.322 159.079 1.00 102.79 ? 66  ASP E CA  1 
ATOM 5712 C C   . ASP E 3 63  ? 148.454 116.074 159.899 1.00 102.79 ? 66  ASP E C   1 
ATOM 5713 O O   . ASP E 3 63  ? 148.382 116.150 161.140 1.00 102.79 ? 66  ASP E O   1 
ATOM 5714 C CB  . ASP E 3 63  ? 149.204 118.397 159.238 1.00 102.79 ? 66  ASP E CB  1 
ATOM 5715 C CG  . ASP E 3 63  ? 150.200 118.435 158.093 1.00 102.79 ? 66  ASP E CG  1 
ATOM 5716 O OD1 . ASP E 3 63  ? 150.020 117.663 157.135 1.00 102.79 ? 66  ASP E OD1 1 
ATOM 5717 O OD2 . ASP E 3 63  ? 151.147 119.241 158.170 1.00 102.79 ? 66  ASP E OD2 1 
ATOM 5718 N N   . PRO E 3 64  ? 148.818 114.937 159.271 1.00 88.71  ? 67  PRO E N   1 
ATOM 5719 C CA  . PRO E 3 64  ? 149.203 113.733 160.025 1.00 88.71  ? 67  PRO E CA  1 
ATOM 5720 C C   . PRO E 3 64  ? 150.403 113.948 160.928 1.00 88.71  ? 67  PRO E C   1 
ATOM 5721 O O   . PRO E 3 64  ? 150.478 113.335 162.000 1.00 88.71  ? 67  PRO E O   1 
ATOM 5722 C CB  . PRO E 3 64  ? 149.498 112.711 158.919 1.00 88.71  ? 67  PRO E CB  1 
ATOM 5723 C CG  . PRO E 3 64  ? 149.841 113.538 157.724 1.00 88.71  ? 67  PRO E CG  1 
ATOM 5724 C CD  . PRO E 3 64  ? 148.986 114.764 157.820 1.00 88.71  ? 67  PRO E CD  1 
ATOM 5725 N N   . LYS E 3 65  ? 151.346 114.801 160.524 1.00 92.56  ? 68  LYS E N   1 
ATOM 5726 C CA  . LYS E 3 65  ? 152.530 115.045 161.340 1.00 92.56  ? 68  LYS E CA  1 
ATOM 5727 C C   . LYS E 3 65  ? 152.165 115.721 162.657 1.00 92.56  ? 68  LYS E C   1 
ATOM 5728 O O   . LYS E 3 65  ? 152.693 115.368 163.718 1.00 92.56  ? 68  LYS E O   1 
ATOM 5729 C CB  . LYS E 3 65  ? 153.533 115.890 160.555 1.00 92.56  ? 68  LYS E CB  1 
ATOM 5730 C CG  . LYS E 3 65  ? 154.026 115.225 159.281 1.00 92.56  ? 68  LYS E CG  1 
ATOM 5731 C CD  . LYS E 3 65  ? 154.858 116.179 158.441 1.00 92.56  ? 68  LYS E CD  1 
ATOM 5732 C CE  . LYS E 3 65  ? 154.024 117.352 157.955 1.00 92.56  ? 68  LYS E CE  1 
ATOM 5733 N NZ  . LYS E 3 65  ? 154.816 118.281 157.104 1.00 92.56  ? 68  LYS E NZ  1 
ATOM 5734 N N   . LEU E 3 66  ? 151.268 116.697 162.609 1.00 106.68 ? 69  LEU E N   1 
ATOM 5735 C CA  . LEU E 3 66  ? 150.867 117.409 163.817 1.00 106.68 ? 69  LEU E CA  1 
ATOM 5736 C C   . LEU E 3 66  ? 149.868 116.572 164.609 1.00 106.68 ? 69  LEU E C   1 
ATOM 5737 O O   . LEU E 3 66  ? 148.857 116.134 164.051 1.00 106.68 ? 69  LEU E O   1 
ATOM 5738 C CB  . LEU E 3 66  ? 150.255 118.763 163.474 1.00 106.68 ? 69  LEU E CB  1 
ATOM 5739 C CG  . LEU E 3 66  ? 151.224 119.886 163.100 1.00 106.68 ? 69  LEU E CG  1 
ATOM 5740 C CD1 . LEU E 3 66  ? 152.365 119.957 164.104 1.00 106.68 ? 69  LEU E CD1 1 
ATOM 5741 C CD2 . LEU E 3 66  ? 151.755 119.731 161.682 1.00 106.68 ? 69  LEU E CD2 1 
ATOM 5742 N N   . PRO E 3 67  ? 150.116 116.322 165.892 1.00 107.60 ? 70  PRO E N   1 
ATOM 5743 C CA  . PRO E 3 67  ? 149.168 115.534 166.686 1.00 107.60 ? 70  PRO E CA  1 
ATOM 5744 C C   . PRO E 3 67  ? 147.901 116.317 166.994 1.00 107.60 ? 70  PRO E C   1 
ATOM 5745 O O   . PRO E 3 67  ? 147.941 117.507 167.317 1.00 107.60 ? 70  PRO E O   1 
ATOM 5746 C CB  . PRO E 3 67  ? 149.954 115.228 167.966 1.00 107.60 ? 70  PRO E CB  1 
ATOM 5747 C CG  . PRO E 3 67  ? 150.905 116.368 168.089 1.00 107.60 ? 70  PRO E CG  1 
ATOM 5748 C CD  . PRO E 3 67  ? 151.286 116.743 166.681 1.00 107.60 ? 70  PRO E CD  1 
ATOM 5749 N N   . TYR E 3 68  ? 146.767 115.632 166.889 1.00 107.78 ? 71  TYR E N   1 
ATOM 5750 C CA  . TYR E 3 68  ? 145.475 116.219 167.218 1.00 107.78 ? 71  TYR E CA  1 
ATOM 5751 C C   . TYR E 3 68  ? 145.051 115.745 168.601 1.00 107.78 ? 71  TYR E C   1 
ATOM 5752 O O   . TYR E 3 68  ? 145.135 114.551 168.905 1.00 107.78 ? 71  TYR E O   1 
ATOM 5753 C CB  . TYR E 3 68  ? 144.421 115.839 166.178 1.00 107.78 ? 71  TYR E CB  1 
ATOM 5754 C CG  . TYR E 3 68  ? 143.220 116.755 166.174 1.00 107.78 ? 71  TYR E CG  1 
ATOM 5755 C CD1 . TYR E 3 68  ? 142.111 116.484 166.962 1.00 107.78 ? 71  TYR E CD1 1 
ATOM 5756 C CD2 . TYR E 3 68  ? 143.200 117.897 165.385 1.00 107.78 ? 71  TYR E CD2 1 
ATOM 5757 C CE1 . TYR E 3 68  ? 141.013 117.323 166.960 1.00 107.78 ? 71  TYR E CE1 1 
ATOM 5758 C CE2 . TYR E 3 68  ? 142.108 118.741 165.377 1.00 107.78 ? 71  TYR E CE2 1 
ATOM 5759 C CZ  . TYR E 3 68  ? 141.018 118.450 166.166 1.00 107.78 ? 71  TYR E CZ  1 
ATOM 5760 O OH  . TYR E 3 68  ? 139.928 119.289 166.161 1.00 107.78 ? 71  TYR E OH  1 
ATOM 5761 N N   . HIS E 3 69  ? 144.599 116.685 169.434 1.00 119.10 ? 72  HIS E N   1 
ATOM 5762 C CA  . HIS E 3 69  ? 144.289 116.413 170.838 1.00 119.10 ? 72  HIS E CA  1 
ATOM 5763 C C   . HIS E 3 69  ? 145.480 115.789 171.559 1.00 119.10 ? 72  HIS E C   1 
ATOM 5764 O O   . HIS E 3 69  ? 145.318 114.880 172.376 1.00 119.10 ? 72  HIS E O   1 
ATOM 5765 C CB  . HIS E 3 69  ? 143.052 115.522 170.981 1.00 119.10 ? 72  HIS E CB  1 
ATOM 5766 C CG  . HIS E 3 69  ? 141.769 116.203 170.619 1.00 119.10 ? 72  HIS E CG  1 
ATOM 5767 N ND1 . HIS E 3 69  ? 140.563 115.538 170.566 1.00 119.10 ? 72  HIS E ND1 1 
ATOM 5768 C CD2 . HIS E 3 69  ? 141.502 117.491 170.298 1.00 119.10 ? 72  HIS E CD2 1 
ATOM 5769 C CE1 . HIS E 3 69  ? 139.609 116.386 170.225 1.00 119.10 ? 72  HIS E CE1 1 
ATOM 5770 N NE2 . HIS E 3 69  ? 140.153 117.578 170.057 1.00 119.10 ? 72  HIS E NE2 1 
ATOM 5771 N N   . ASP E 3 70  ? 146.685 116.270 171.243 1.00 116.45 ? 73  ASP E N   1 
ATOM 5772 C CA  . ASP E 3 70  ? 147.932 115.766 171.814 1.00 116.45 ? 73  ASP E CA  1 
ATOM 5773 C C   . ASP E 3 70  ? 148.109 114.269 171.577 1.00 116.45 ? 73  ASP E C   1 
ATOM 5774 O O   . ASP E 3 70  ? 148.739 113.577 172.380 1.00 116.45 ? 73  ASP E O   1 
ATOM 5775 C CB  . ASP E 3 70  ? 148.030 116.084 173.310 1.00 116.45 ? 73  ASP E CB  1 
ATOM 5776 C CG  . ASP E 3 70  ? 147.924 117.569 173.597 1.00 116.45 ? 73  ASP E CG  1 
ATOM 5777 O OD1 . ASP E 3 70  ? 148.286 118.373 172.712 1.00 116.45 ? 73  ASP E OD1 1 
ATOM 5778 O OD2 . ASP E 3 70  ? 147.480 117.933 174.706 1.00 116.45 ? 73  ASP E OD2 1 
ATOM 5779 N N   . PHE E 3 71  ? 147.563 113.755 170.477 1.00 118.40 ? 74  PHE E N   1 
ATOM 5780 C CA  . PHE E 3 71  ? 147.643 112.339 170.148 1.00 118.40 ? 74  PHE E CA  1 
ATOM 5781 C C   . PHE E 3 71  ? 148.192 112.181 168.739 1.00 118.40 ? 74  PHE E C   1 
ATOM 5782 O O   . PHE E 3 71  ? 147.716 112.837 167.807 1.00 118.40 ? 74  PHE E O   1 
ATOM 5783 C CB  . PHE E 3 71  ? 146.271 111.670 170.272 1.00 118.40 ? 74  PHE E CB  1 
ATOM 5784 C CG  . PHE E 3 71  ? 145.747 111.623 171.680 1.00 118.40 ? 74  PHE E CG  1 
ATOM 5785 C CD1 . PHE E 3 71  ? 146.586 111.302 172.731 1.00 118.40 ? 74  PHE E CD1 1 
ATOM 5786 C CD2 . PHE E 3 71  ? 144.420 111.908 171.951 1.00 118.40 ? 74  PHE E CD2 1 
ATOM 5787 C CE1 . PHE E 3 71  ? 146.109 111.259 174.029 1.00 118.40 ? 74  PHE E CE1 1 
ATOM 5788 C CE2 . PHE E 3 71  ? 143.937 111.867 173.244 1.00 118.40 ? 74  PHE E CE2 1 
ATOM 5789 C CZ  . PHE E 3 71  ? 144.783 111.542 174.285 1.00 118.40 ? 74  PHE E CZ  1 
ATOM 5790 N N   . ILE E 3 72  ? 149.187 111.308 168.589 1.00 112.02 ? 75  ILE E N   1 
ATOM 5791 C CA  . ILE E 3 72  ? 149.860 111.136 167.308 1.00 112.02 ? 75  ILE E CA  1 
ATOM 5792 C C   . ILE E 3 72  ? 149.045 110.213 166.407 1.00 112.02 ? 75  ILE E C   1 
ATOM 5793 O O   . ILE E 3 72  ? 148.348 109.302 166.862 1.00 112.02 ? 75  ILE E O   1 
ATOM 5794 C CB  . ILE E 3 72  ? 151.290 110.602 167.512 1.00 112.02 ? 75  ILE E CB  1 
ATOM 5795 C CG1 . ILE E 3 72  ? 152.002 111.401 168.604 1.00 112.02 ? 75  ILE E CG1 1 
ATOM 5796 C CG2 . ILE E 3 72  ? 152.087 110.672 166.220 1.00 112.02 ? 75  ILE E CG2 1 
ATOM 5797 C CD1 . ILE E 3 72  ? 153.433 110.969 168.842 1.00 112.02 ? 75  ILE E CD1 1 
ATOM 5798 N N   . LEU E 3 73  ? 149.140 110.456 165.102 1.00 103.03 ? 76  LEU E N   1 
ATOM 5799 C CA  . LEU E 3 73  ? 148.442 109.669 164.095 1.00 103.03 ? 76  LEU E CA  1 
ATOM 5800 C C   . LEU E 3 73  ? 149.364 108.575 163.572 1.00 103.03 ? 76  LEU E C   1 
ATOM 5801 O O   . LEU E 3 73  ? 150.516 108.845 163.219 1.00 103.03 ? 76  LEU E O   1 
ATOM 5802 C CB  . LEU E 3 73  ? 147.971 110.553 162.939 1.00 103.03 ? 76  LEU E CB  1 
ATOM 5803 C CG  . LEU E 3 73  ? 146.651 111.315 163.079 1.00 103.03 ? 76  LEU E CG  1 
ATOM 5804 C CD1 . LEU E 3 73  ? 146.675 112.289 164.246 1.00 103.03 ? 76  LEU E CD1 1 
ATOM 5805 C CD2 . LEU E 3 73  ? 146.342 112.047 161.785 1.00 103.03 ? 76  LEU E CD2 1 
ATOM 5806 N N   . GLU E 3 74  ? 148.852 107.342 163.524 1.00 111.89 ? 77  GLU E N   1 
ATOM 5807 C CA  . GLU E 3 74  ? 149.620 106.200 163.039 1.00 111.89 ? 77  GLU E CA  1 
ATOM 5808 C C   . GLU E 3 74  ? 148.901 105.466 161.913 1.00 111.89 ? 77  GLU E C   1 
ATOM 5809 O O   . GLU E 3 74  ? 149.280 104.340 161.574 1.00 111.89 ? 77  GLU E O   1 
ATOM 5810 C CB  . GLU E 3 74  ? 149.930 105.231 164.183 1.00 111.89 ? 77  GLU E CB  1 
ATOM 5811 C CG  . GLU E 3 74  ? 150.737 105.841 165.315 1.00 111.89 ? 77  GLU E CG  1 
ATOM 5812 C CD  . GLU E 3 74  ? 151.023 104.850 166.426 1.00 111.89 ? 77  GLU E CD  1 
ATOM 5813 O OE1 . GLU E 3 74  ? 150.609 103.678 166.300 1.00 111.89 ? 77  GLU E OE1 1 
ATOM 5814 O OE2 . GLU E 3 74  ? 151.662 105.242 167.424 1.00 111.89 ? 77  GLU E OE2 1 
ATOM 5815 N N   . ASP E 3 75  ? 147.871 106.077 161.326 1.00 105.96 ? 78  ASP E N   1 
ATOM 5816 C CA  . ASP E 3 75  ? 147.101 105.418 160.278 1.00 105.96 ? 78  ASP E CA  1 
ATOM 5817 C C   . ASP E 3 75  ? 146.762 106.359 159.127 1.00 105.96 ? 78  ASP E C   1 
ATOM 5818 O O   . ASP E 3 75  ? 145.703 106.205 158.507 1.00 105.96 ? 78  ASP E O   1 
ATOM 5819 C CB  . ASP E 3 75  ? 145.818 104.820 160.855 1.00 105.96 ? 78  ASP E CB  1 
ATOM 5820 C CG  . ASP E 3 75  ? 145.161 105.729 161.873 1.00 105.96 ? 78  ASP E CG  1 
ATOM 5821 O OD1 . ASP E 3 75  ? 145.733 106.799 162.170 1.00 105.96 ? 78  ASP E OD1 1 
ATOM 5822 O OD2 . ASP E 3 75  ? 144.077 105.373 162.379 1.00 105.96 ? 78  ASP E OD2 1 
ATOM 5823 N N   . ALA E 3 76  ? 147.629 107.329 158.828 1.00 109.80 ? 79  ALA E N   1 
ATOM 5824 C CA  . ALA E 3 76  ? 147.350 108.271 157.750 1.00 109.80 ? 79  ALA E CA  1 
ATOM 5825 C C   . ALA E 3 76  ? 147.251 107.574 156.400 1.00 109.80 ? 79  ALA E C   1 
ATOM 5826 O O   . ALA E 3 76  ? 146.574 108.071 155.494 1.00 109.80 ? 79  ALA E O   1 
ATOM 5827 C CB  . ALA E 3 76  ? 148.426 109.355 157.707 1.00 109.80 ? 79  ALA E CB  1 
ATOM 5828 N N   . ALA E 3 77  ? 147.914 106.434 156.243 1.00 107.43 ? 80  ALA E N   1 
ATOM 5829 C CA  . ALA E 3 77  ? 147.896 105.696 154.989 1.00 107.43 ? 80  ALA E CA  1 
ATOM 5830 C C   . ALA E 3 77  ? 146.677 104.795 154.849 1.00 107.43 ? 80  ALA E C   1 
ATOM 5831 O O   . ALA E 3 77  ? 146.518 104.152 153.806 1.00 107.43 ? 80  ALA E O   1 
ATOM 5832 C CB  . ALA E 3 77  ? 149.171 104.859 154.851 1.00 107.43 ? 80  ALA E CB  1 
ATOM 5833 N N   . SER E 3 78  ? 145.823 104.729 155.862 1.00 93.07  ? 81  SER E N   1 
ATOM 5834 C CA  . SER E 3 78  ? 144.680 103.832 155.812 1.00 93.07  ? 81  SER E CA  1 
ATOM 5835 C C   . SER E 3 78  ? 143.685 104.304 154.757 1.00 93.07  ? 81  SER E C   1 
ATOM 5836 O O   . SER E 3 78  ? 143.274 105.472 154.778 1.00 93.07  ? 81  SER E O   1 
ATOM 5837 C CB  . SER E 3 78  ? 143.999 103.756 157.177 1.00 93.07  ? 81  SER E CB  1 
ATOM 5838 O OG  . SER E 3 78  ? 144.876 103.223 158.153 1.00 93.07  ? 81  SER E OG  1 
ATOM 5839 N N   . PRO E 3 79  ? 143.282 103.442 153.821 1.00 104.21 ? 82  PRO E N   1 
ATOM 5840 C CA  . PRO E 3 79  ? 142.250 103.842 152.852 1.00 104.21 ? 82  PRO E CA  1 
ATOM 5841 C C   . PRO E 3 79  ? 140.924 104.197 153.498 1.00 104.21 ? 82  PRO E C   1 
ATOM 5842 O O   . PRO E 3 79  ? 140.205 105.055 152.972 1.00 104.21 ? 82  PRO E O   1 
ATOM 5843 C CB  . PRO E 3 79  ? 142.122 102.610 151.947 1.00 104.21 ? 82  PRO E CB  1 
ATOM 5844 C CG  . PRO E 3 79  ? 142.601 101.472 152.789 1.00 104.21 ? 82  PRO E CG  1 
ATOM 5845 C CD  . PRO E 3 79  ? 143.694 102.039 153.648 1.00 104.21 ? 82  PRO E CD  1 
ATOM 5846 N N   . LYS E 3 80  ? 140.578 103.571 154.620 1.00 113.13 ? 83  LYS E N   1 
ATOM 5847 C CA  . LYS E 3 80  ? 139.336 103.857 155.318 1.00 113.13 ? 83  LYS E CA  1 
ATOM 5848 C C   . LYS E 3 80  ? 139.644 104.162 156.775 1.00 113.13 ? 83  LYS E C   1 
ATOM 5849 O O   . LYS E 3 80  ? 140.659 103.718 157.317 1.00 113.13 ? 83  LYS E O   1 
ATOM 5850 C CB  . LYS E 3 80  ? 138.346 102.691 155.207 1.00 113.13 ? 83  LYS E CB  1 
ATOM 5851 C CG  . LYS E 3 80  ? 138.837 101.398 155.828 1.00 113.13 ? 83  LYS E CG  1 
ATOM 5852 C CD  . LYS E 3 80  ? 137.803 100.294 155.678 1.00 113.13 ? 83  LYS E CD  1 
ATOM 5853 C CE  . LYS E 3 80  ? 137.641 99.883  154.224 1.00 113.13 ? 83  LYS E CE  1 
ATOM 5854 N NZ  . LYS E 3 80  ? 136.631 98.801  154.060 1.00 113.13 ? 83  LYS E NZ  1 
ATOM 5855 N N   . CYS E 3 81  ? 138.755 104.925 157.405 1.00 116.87 ? 84  CYS E N   1 
ATOM 5856 C CA  . CYS E 3 81  ? 138.974 105.427 158.760 1.00 116.87 ? 84  CYS E CA  1 
ATOM 5857 C C   . CYS E 3 81  ? 138.768 104.286 159.748 1.00 116.87 ? 84  CYS E C   1 
ATOM 5858 O O   . CYS E 3 81  ? 137.666 104.050 160.244 1.00 116.87 ? 84  CYS E O   1 
ATOM 5859 C CB  . CYS E 3 81  ? 138.039 106.594 159.053 1.00 116.87 ? 84  CYS E CB  1 
ATOM 5860 S SG  . CYS E 3 81  ? 138.780 107.938 160.006 1.00 116.87 ? 84  CYS E SG  1 
ATOM 5861 N N   . ILE E 3 82  ? 139.848 103.566 160.036 1.00 119.54 ? 85  ILE E N   1 
ATOM 5862 C CA  . ILE E 3 82  ? 139.814 102.503 161.033 1.00 119.54 ? 85  ILE E CA  1 
ATOM 5863 C C   . ILE E 3 82  ? 139.782 103.138 162.415 1.00 119.54 ? 85  ILE E C   1 
ATOM 5864 O O   . ILE E 3 82  ? 140.798 103.649 162.901 1.00 119.54 ? 85  ILE E O   1 
ATOM 5865 C CB  . ILE E 3 82  ? 141.027 101.571 160.882 1.00 119.54 ? 85  ILE E CB  1 
ATOM 5866 C CG1 . ILE E 3 82  ? 140.966 100.809 159.556 1.00 119.54 ? 85  ILE E CG1 1 
ATOM 5867 C CG2 . ILE E 3 82  ? 141.101 100.599 162.051 1.00 119.54 ? 85  ILE E CG2 1 
ATOM 5868 C CD1 . ILE E 3 82  ? 142.236 100.074 159.207 1.00 119.54 ? 85  ILE E CD1 1 
ATOM 5869 N N   . MET E 3 83  ? 138.615 103.109 163.053 1.00 129.42 ? 86  MET E N   1 
ATOM 5870 C CA  . MET E 3 83  ? 138.439 103.779 164.334 1.00 129.42 ? 86  MET E CA  1 
ATOM 5871 C C   . MET E 3 83  ? 139.212 103.047 165.423 1.00 129.42 ? 86  MET E C   1 
ATOM 5872 O O   . MET E 3 83  ? 139.112 101.822 165.552 1.00 129.42 ? 86  MET E O   1 
ATOM 5873 C CB  . MET E 3 83  ? 136.956 103.861 164.691 1.00 129.42 ? 86  MET E CB  1 
ATOM 5874 C CG  . MET E 3 83  ? 136.672 104.701 165.916 1.00 129.42 ? 86  MET E CG  1 
ATOM 5875 S SD  . MET E 3 83  ? 137.421 106.334 165.791 1.00 129.42 ? 86  MET E SD  1 
ATOM 5876 C CE  . MET E 3 83  ? 136.189 107.234 164.859 1.00 129.42 ? 86  MET E CE  1 
ATOM 5877 N N   . LYS E 3 84  ? 139.984 103.800 166.205 1.00 119.92 ? 87  LYS E N   1 
ATOM 5878 C CA  . LYS E 3 84  ? 140.805 103.236 167.267 1.00 119.92 ? 87  LYS E CA  1 
ATOM 5879 C C   . LYS E 3 84  ? 140.536 103.971 168.571 1.00 119.92 ? 87  LYS E C   1 
ATOM 5880 O O   . LYS E 3 84  ? 140.531 105.205 168.606 1.00 119.92 ? 87  LYS E O   1 
ATOM 5881 C CB  . LYS E 3 84  ? 142.295 103.319 166.918 1.00 119.92 ? 87  LYS E CB  1 
ATOM 5882 C CG  . LYS E 3 84  ? 143.204 102.615 167.909 1.00 119.92 ? 87  LYS E CG  1 
ATOM 5883 C CD  . LYS E 3 84  ? 142.955 101.118 167.908 1.00 119.92 ? 87  LYS E CD  1 
ATOM 5884 C CE  . LYS E 3 84  ? 143.224 100.520 166.536 1.00 119.92 ? 87  LYS E CE  1 
ATOM 5885 N NZ  . LYS E 3 84  ? 142.993 99.049  166.516 1.00 119.92 ? 87  LYS E NZ  1 
ATOM 5886 N N   . GLU E 3 85  ? 140.309 103.211 169.638 1.00 116.86 ? 88  GLU E N   1 
ATOM 5887 C CA  . GLU E 3 85  ? 140.085 103.797 170.949 1.00 116.86 ? 88  GLU E CA  1 
ATOM 5888 C C   . GLU E 3 85  ? 141.388 104.349 171.519 1.00 116.86 ? 88  GLU E C   1 
ATOM 5889 O O   . GLU E 3 85  ? 142.463 103.766 171.361 1.00 116.86 ? 88  GLU E O   1 
ATOM 5890 C CB  . GLU E 3 85  ? 139.493 102.762 171.908 1.00 116.86 ? 88  GLU E CB  1 
ATOM 5891 C CG  . GLU E 3 85  ? 139.125 103.315 173.276 1.00 116.86 ? 88  GLU E CG  1 
ATOM 5892 C CD  . GLU E 3 85  ? 138.619 102.244 174.223 1.00 116.86 ? 88  GLU E CD  1 
ATOM 5893 O OE1 . GLU E 3 85  ? 138.602 101.059 173.829 1.00 116.86 ? 88  GLU E OE1 1 
ATOM 5894 O OE2 . GLU E 3 85  ? 138.237 102.588 175.361 1.00 116.86 ? 88  GLU E OE2 1 
ATOM 5895 N N   . LYS E 3 86  ? 141.281 105.490 172.192 1.00 127.72 ? 89  LYS E N   1 
ATOM 5896 C CA  . LYS E 3 86  ? 142.413 106.103 172.866 1.00 127.72 ? 89  LYS E CA  1 
ATOM 5897 C C   . LYS E 3 86  ? 142.124 106.157 174.361 1.00 127.72 ? 89  LYS E C   1 
ATOM 5898 O O   . LYS E 3 86  ? 141.003 105.901 174.809 1.00 127.72 ? 89  LYS E O   1 
ATOM 5899 C CB  . LYS E 3 86  ? 142.715 107.497 172.303 1.00 127.72 ? 89  LYS E CB  1 
ATOM 5900 C CG  . LYS E 3 86  ? 143.328 107.460 170.916 1.00 127.72 ? 89  LYS E CG  1 
ATOM 5901 C CD  . LYS E 3 86  ? 143.722 108.844 170.439 1.00 127.72 ? 89  LYS E CD  1 
ATOM 5902 C CE  . LYS E 3 86  ? 144.341 108.789 169.052 1.00 127.72 ? 89  LYS E CE  1 
ATOM 5903 N NZ  . LYS E 3 86  ? 145.583 107.970 169.028 1.00 127.72 ? 89  LYS E NZ  1 
ATOM 5904 N N   . LYS E 3 87  ? 143.150 106.495 175.139 1.00 152.94 ? 90  LYS E N   1 
ATOM 5905 C CA  . LYS E 3 87  ? 143.115 106.355 176.594 1.00 152.94 ? 90  LYS E CA  1 
ATOM 5906 C C   . LYS E 3 87  ? 142.874 107.681 177.305 1.00 152.94 ? 90  LYS E C   1 
ATOM 5907 O O   . LYS E 3 87  ? 143.451 107.937 178.366 1.00 152.94 ? 90  LYS E O   1 
ATOM 5908 C CB  . LYS E 3 87  ? 144.404 105.708 177.091 1.00 152.94 ? 90  LYS E CB  1 
ATOM 5909 C CG  . LYS E 3 87  ? 145.674 106.427 176.665 1.00 152.94 ? 90  LYS E CG  1 
ATOM 5910 C CD  . LYS E 3 87  ? 146.904 105.758 177.254 1.00 152.94 ? 90  LYS E CD  1 
ATOM 5911 C CE  . LYS E 3 87  ? 146.838 105.724 178.772 1.00 152.94 ? 90  LYS E CE  1 
ATOM 5912 N NZ  . LYS E 3 87  ? 148.028 105.053 179.363 1.00 152.94 ? 90  LYS E NZ  1 
ATOM 5913 N N   . LYS E 3 88  ? 142.029 108.540 176.748 1.00 169.27 ? 91  LYS E N   1 
ATOM 5914 C CA  . LYS E 3 88  ? 141.660 109.777 177.423 1.00 169.27 ? 91  LYS E CA  1 
ATOM 5915 C C   . LYS E 3 88  ? 140.914 109.452 178.713 1.00 169.27 ? 91  LYS E C   1 
ATOM 5916 O O   . LYS E 3 88  ? 139.894 108.748 178.669 1.00 169.27 ? 91  LYS E O   1 
ATOM 5917 C CB  . LYS E 3 88  ? 140.793 110.643 176.512 1.00 169.27 ? 91  LYS E CB  1 
ATOM 5918 C CG  . LYS E 3 88  ? 140.344 111.955 177.136 1.00 169.27 ? 91  LYS E CG  1 
ATOM 5919 C CD  . LYS E 3 88  ? 141.510 112.912 177.327 1.00 169.27 ? 91  LYS E CD  1 
ATOM 5920 C CE  . LYS E 3 88  ? 142.118 113.318 175.994 1.00 169.27 ? 91  LYS E CE  1 
ATOM 5921 N NZ  . LYS E 3 88  ? 143.248 114.272 176.167 1.00 169.27 ? 91  LYS E NZ  1 
ATOM 5922 N N   . PRO E 3 89  ? 141.380 109.927 179.868 1.00 167.79 ? 92  PRO E N   1 
ATOM 5923 C CA  . PRO E 3 89  ? 140.723 109.568 181.131 1.00 167.79 ? 92  PRO E CA  1 
ATOM 5924 C C   . PRO E 3 89  ? 139.326 110.163 181.234 1.00 167.79 ? 92  PRO E C   1 
ATOM 5925 O O   . PRO E 3 89  ? 139.043 111.236 180.697 1.00 167.79 ? 92  PRO E O   1 
ATOM 5926 C CB  . PRO E 3 89  ? 141.663 110.146 182.195 1.00 167.79 ? 92  PRO E CB  1 
ATOM 5927 C CG  . PRO E 3 89  ? 142.375 111.259 181.499 1.00 167.79 ? 92  PRO E CG  1 
ATOM 5928 C CD  . PRO E 3 89  ? 142.544 110.804 180.078 1.00 167.79 ? 92  PRO E CD  1 
ATOM 5929 N N   . GLY E 3 90  ? 138.450 109.448 181.936 1.00 159.44 ? 93  GLY E N   1 
ATOM 5930 C CA  . GLY E 3 90  ? 137.101 109.917 182.185 1.00 159.44 ? 93  GLY E CA  1 
ATOM 5931 C C   . GLY E 3 90  ? 136.148 109.702 181.028 1.00 159.44 ? 93  GLY E C   1 
ATOM 5932 O O   . GLY E 3 90  ? 135.275 108.832 181.085 1.00 159.44 ? 93  GLY E O   1 
ATOM 5933 N N   . GLU E 3 91  ? 136.307 110.492 179.971 1.00 168.99 ? 94  GLU E N   1 
ATOM 5934 C CA  . GLU E 3 91  ? 135.422 110.411 178.820 1.00 168.99 ? 94  GLU E CA  1 
ATOM 5935 C C   . GLU E 3 91  ? 135.916 109.366 177.826 1.00 168.99 ? 94  GLU E C   1 
ATOM 5936 O O   . GLU E 3 91  ? 137.119 109.123 177.691 1.00 168.99 ? 94  GLU E O   1 
ATOM 5937 C CB  . GLU E 3 91  ? 135.308 111.772 178.132 1.00 168.99 ? 94  GLU E CB  1 
ATOM 5938 C CG  . GLU E 3 91  ? 136.639 112.439 177.809 1.00 168.99 ? 94  GLU E CG  1 
ATOM 5939 C CD  . GLU E 3 91  ? 137.192 113.244 178.971 1.00 168.99 ? 94  GLU E CD  1 
ATOM 5940 O OE1 . GLU E 3 91  ? 136.560 113.248 180.049 1.00 168.99 ? 94  GLU E OE1 1 
ATOM 5941 O OE2 . GLU E 3 91  ? 138.257 113.875 178.806 1.00 168.99 ? 94  GLU E OE2 1 
ATOM 5942 N N   . THR E 3 92  ? 134.969 108.745 177.126 1.00 165.02 ? 95  THR E N   1 
ATOM 5943 C CA  . THR E 3 92  ? 135.305 107.746 176.120 1.00 165.02 ? 95  THR E CA  1 
ATOM 5944 C C   . THR E 3 92  ? 135.775 108.441 174.848 1.00 165.02 ? 95  THR E C   1 
ATOM 5945 O O   . THR E 3 92  ? 135.125 109.372 174.366 1.00 165.02 ? 95  THR E O   1 
ATOM 5946 C CB  . THR E 3 92  ? 134.099 106.855 175.826 1.00 165.02 ? 95  THR E CB  1 
ATOM 5947 O OG1 . THR E 3 92  ? 133.708 106.169 177.022 1.00 165.02 ? 95  THR E OG1 1 
ATOM 5948 C CG2 . THR E 3 92  ? 134.440 105.833 174.754 1.00 165.02 ? 95  THR E CG2 1 
ATOM 5949 N N   . PHE E 3 93  ? 136.904 107.992 174.305 1.00 132.69 ? 96  PHE E N   1 
ATOM 5950 C CA  . PHE E 3 93  ? 137.546 108.684 173.196 1.00 132.69 ? 96  PHE E CA  1 
ATOM 5951 C C   . PHE E 3 93  ? 137.943 107.700 172.107 1.00 132.69 ? 96  PHE E C   1 
ATOM 5952 O O   . PHE E 3 93  ? 138.652 106.722 172.370 1.00 132.69 ? 96  PHE E O   1 
ATOM 5953 C CB  . PHE E 3 93  ? 138.775 109.453 173.685 1.00 132.69 ? 96  PHE E CB  1 
ATOM 5954 C CG  . PHE E 3 93  ? 139.314 110.432 172.689 1.00 132.69 ? 96  PHE E CG  1 
ATOM 5955 C CD1 . PHE E 3 93  ? 140.360 110.086 171.857 1.00 132.69 ? 96  PHE E CD1 1 
ATOM 5956 C CD2 . PHE E 3 93  ? 138.781 111.705 172.595 1.00 132.69 ? 96  PHE E CD2 1 
ATOM 5957 C CE1 . PHE E 3 93  ? 140.862 110.988 170.946 1.00 132.69 ? 96  PHE E CE1 1 
ATOM 5958 C CE2 . PHE E 3 93  ? 139.280 112.612 171.692 1.00 132.69 ? 96  PHE E CE2 1 
ATOM 5959 C CZ  . PHE E 3 93  ? 140.320 112.254 170.863 1.00 132.69 ? 96  PHE E CZ  1 
ATOM 5960 N N   . PHE E 3 94  ? 137.508 107.977 170.880 1.00 123.14 ? 97  PHE E N   1 
ATOM 5961 C CA  . PHE E 3 94  ? 137.911 107.212 169.711 1.00 123.14 ? 97  PHE E CA  1 
ATOM 5962 C C   . PHE E 3 94  ? 138.404 108.183 168.650 1.00 123.14 ? 97  PHE E C   1 
ATOM 5963 O O   . PHE E 3 94  ? 137.863 109.279 168.500 1.00 123.14 ? 97  PHE E O   1 
ATOM 5964 C CB  . PHE E 3 94  ? 136.751 106.369 169.164 1.00 123.14 ? 97  PHE E CB  1 
ATOM 5965 C CG  . PHE E 3 94  ? 136.465 105.128 169.962 1.00 123.14 ? 97  PHE E CG  1 
ATOM 5966 C CD1 . PHE E 3 94  ? 135.871 105.209 171.210 1.00 123.14 ? 97  PHE E CD1 1 
ATOM 5967 C CD2 . PHE E 3 94  ? 136.778 103.877 169.455 1.00 123.14 ? 97  PHE E CD2 1 
ATOM 5968 C CE1 . PHE E 3 94  ? 135.605 104.067 171.942 1.00 123.14 ? 97  PHE E CE1 1 
ATOM 5969 C CE2 . PHE E 3 94  ? 136.511 102.732 170.181 1.00 123.14 ? 97  PHE E CE2 1 
ATOM 5970 C CZ  . PHE E 3 94  ? 135.926 102.828 171.427 1.00 123.14 ? 97  PHE E CZ  1 
ATOM 5971 N N   . MET E 3 95  ? 139.441 107.786 167.921 1.00 117.37 ? 98  MET E N   1 
ATOM 5972 C CA  . MET E 3 95  ? 139.956 108.625 166.851 1.00 117.37 ? 98  MET E CA  1 
ATOM 5973 C C   . MET E 3 95  ? 140.364 107.746 165.680 1.00 117.37 ? 98  MET E C   1 
ATOM 5974 O O   . MET E 3 95  ? 140.774 106.595 165.860 1.00 117.37 ? 98  MET E O   1 
ATOM 5975 C CB  . MET E 3 95  ? 141.143 109.480 167.315 1.00 117.37 ? 98  MET E CB  1 
ATOM 5976 C CG  . MET E 3 95  ? 141.651 110.458 166.261 1.00 117.37 ? 98  MET E CG  1 
ATOM 5977 S SD  . MET E 3 95  ? 143.158 111.323 166.737 1.00 117.37 ? 98  MET E SD  1 
ATOM 5978 C CE  . MET E 3 95  ? 142.572 112.291 168.122 1.00 117.37 ? 98  MET E CE  1 
ATOM 5979 N N   . CYS E 3 96  ? 140.220 108.293 164.476 1.00 107.89 ? 99  CYS E N   1 
ATOM 5980 C CA  . CYS E 3 96  ? 140.695 107.627 163.275 1.00 107.89 ? 99  CYS E CA  1 
ATOM 5981 C C   . CYS E 3 96  ? 141.137 108.682 162.276 1.00 107.89 ? 99  CYS E C   1 
ATOM 5982 O O   . CYS E 3 96  ? 140.740 109.846 162.353 1.00 107.89 ? 99  CYS E O   1 
ATOM 5983 C CB  . CYS E 3 96  ? 139.625 106.717 162.659 1.00 107.89 ? 99  CYS E CB  1 
ATOM 5984 S SG  . CYS E 3 96  ? 138.221 107.580 161.925 1.00 107.89 ? 99  CYS E SG  1 
ATOM 5985 N N   . SER E 3 97  ? 141.974 108.258 161.337 1.00 98.52  ? 100 SER E N   1 
ATOM 5986 C CA  . SER E 3 97  ? 142.438 109.133 160.275 1.00 98.52  ? 100 SER E CA  1 
ATOM 5987 C C   . SER E 3 97  ? 142.560 108.314 159.002 1.00 98.52  ? 100 SER E C   1 
ATOM 5988 O O   . SER E 3 97  ? 142.803 107.106 159.057 1.00 98.52  ? 100 SER E O   1 
ATOM 5989 C CB  . SER E 3 97  ? 143.779 109.781 160.623 1.00 98.52  ? 100 SER E CB  1 
ATOM 5990 O OG  . SER E 3 97  ? 144.271 110.535 159.531 1.00 98.52  ? 100 SER E OG  1 
ATOM 5991 N N   . CYS E 3 98  ? 142.391 108.977 157.862 1.00 93.70  ? 101 CYS E N   1 
ATOM 5992 C CA  . CYS E 3 98  ? 142.439 108.291 156.579 1.00 93.70  ? 101 CYS E CA  1 
ATOM 5993 C C   . CYS E 3 98  ? 142.792 109.288 155.485 1.00 93.70  ? 101 CYS E C   1 
ATOM 5994 O O   . CYS E 3 98  ? 142.865 110.498 155.714 1.00 93.70  ? 101 CYS E O   1 
ATOM 5995 C CB  . CYS E 3 98  ? 141.117 107.576 156.283 1.00 93.70  ? 101 CYS E CB  1 
ATOM 5996 S SG  . CYS E 3 98  ? 139.644 108.565 156.570 1.00 93.70  ? 101 CYS E SG  1 
ATOM 5997 N N   . SER E 3 99  ? 143.030 108.757 154.285 1.00 87.16  ? 102 SER E N   1 
ATOM 5998 C CA  . SER E 3 99  ? 143.489 109.565 153.166 1.00 87.16  ? 102 SER E CA  1 
ATOM 5999 C C   . SER E 3 99  ? 142.624 109.469 151.920 1.00 87.16  ? 102 SER E C   1 
ATOM 6000 O O   . SER E 3 99  ? 142.950 110.121 150.922 1.00 87.16  ? 102 SER E O   1 
ATOM 6001 C CB  . SER E 3 99  ? 144.929 109.190 152.787 1.00 87.16  ? 102 SER E CB  1 
ATOM 6002 O OG  . SER E 3 99  ? 145.379 109.970 151.695 1.00 87.16  ? 102 SER E OG  1 
ATOM 6003 N N   . SER E 3 100 ? 141.559 108.675 151.927 1.00 85.62  ? 103 SER E N   1 
ATOM 6004 C CA  . SER E 3 100 ? 140.660 108.643 150.784 1.00 85.62  ? 103 SER E CA  1 
ATOM 6005 C C   . SER E 3 100 ? 139.717 109.839 150.818 1.00 85.62  ? 103 SER E C   1 
ATOM 6006 O O   . SER E 3 100 ? 139.513 110.467 151.858 1.00 85.62  ? 103 SER E O   1 
ATOM 6007 C CB  . SER E 3 100 ? 139.860 107.344 150.768 1.00 85.62  ? 103 SER E CB  1 
ATOM 6008 O OG  . SER E 3 100 ? 138.914 107.348 149.715 1.00 85.62  ? 103 SER E OG  1 
ATOM 6009 N N   . ASP E 3 101 ? 139.144 110.159 149.662 1.00 83.90  ? 104 ASP E N   1 
ATOM 6010 C CA  . ASP E 3 101 ? 138.208 111.272 149.593 1.00 83.90  ? 104 ASP E CA  1 
ATOM 6011 C C   . ASP E 3 101 ? 136.908 110.915 150.301 1.00 83.90  ? 104 ASP E C   1 
ATOM 6012 O O   . ASP E 3 101 ? 136.321 109.857 150.060 1.00 83.90  ? 104 ASP E O   1 
ATOM 6013 C CB  . ASP E 3 101 ? 137.937 111.651 148.139 1.00 83.90  ? 104 ASP E CB  1 
ATOM 6014 C CG  . ASP E 3 101 ? 139.112 112.355 147.492 1.00 83.90  ? 104 ASP E CG  1 
ATOM 6015 O OD1 . ASP E 3 101 ? 140.106 112.624 148.199 1.00 83.90  ? 104 ASP E OD1 1 
ATOM 6016 O OD2 . ASP E 3 101 ? 139.043 112.641 146.278 1.00 83.90  ? 104 ASP E OD2 1 
ATOM 6017 N N   . GLU E 3 102 ? 136.463 111.811 151.184 1.00 90.93  ? 105 GLU E N   1 
ATOM 6018 C CA  . GLU E 3 102 ? 135.268 111.597 152.000 1.00 90.93  ? 105 GLU E CA  1 
ATOM 6019 C C   . GLU E 3 102 ? 135.364 110.304 152.801 1.00 90.93  ? 105 GLU E C   1 
ATOM 6020 O O   . GLU E 3 102 ? 134.358 109.645 153.066 1.00 90.93  ? 105 GLU E O   1 
ATOM 6021 C CB  . GLU E 3 102 ? 133.998 111.601 151.148 1.00 90.93  ? 105 GLU E CB  1 
ATOM 6022 C CG  . GLU E 3 102 ? 133.535 112.975 150.717 1.00 90.93  ? 105 GLU E CG  1 
ATOM 6023 C CD  . GLU E 3 102 ? 132.141 112.947 150.128 1.00 90.93  ? 105 GLU E CD  1 
ATOM 6024 O OE1 . GLU E 3 102 ? 131.640 111.839 149.839 1.00 90.93  ? 105 GLU E OE1 1 
ATOM 6025 O OE2 . GLU E 3 102 ? 131.543 114.029 149.960 1.00 90.93  ? 105 GLU E OE2 1 
ATOM 6026 N N   . CYS E 3 103 ? 136.583 109.931 153.193 1.00 102.68 ? 106 CYS E N   1 
ATOM 6027 C CA  . CYS E 3 103 ? 136.761 108.686 153.931 1.00 102.68 ? 106 CYS E CA  1 
ATOM 6028 C C   . CYS E 3 103 ? 136.248 108.801 155.359 1.00 102.68 ? 106 CYS E C   1 
ATOM 6029 O O   . CYS E 3 103 ? 135.806 107.804 155.939 1.00 102.68 ? 106 CYS E O   1 
ATOM 6030 C CB  . CYS E 3 103 ? 138.231 108.278 153.923 1.00 102.68 ? 106 CYS E CB  1 
ATOM 6031 S SG  . CYS E 3 103 ? 139.311 109.436 154.771 1.00 102.68 ? 106 CYS E SG  1 
ATOM 6032 N N   . ASN E 3 104 ? 136.285 109.995 155.935 1.00 86.92  ? 107 ASN E N   1 
ATOM 6033 C CA  . ASN E 3 104 ? 135.787 110.160 157.296 1.00 86.92  ? 107 ASN E CA  1 
ATOM 6034 C C   . ASN E 3 104 ? 134.281 110.194 157.365 1.00 86.92  ? 107 ASN E C   1 
ATOM 6035 O O   . ASN E 3 104 ? 133.737 110.290 158.471 1.00 86.92  ? 107 ASN E O   1 
ATOM 6036 C CB  . ASN E 3 104 ? 136.369 111.427 157.920 1.00 86.92  ? 107 ASN E CB  1 
ATOM 6037 C CG  . ASN E 3 104 ? 135.954 112.674 157.187 1.00 86.92  ? 107 ASN E CG  1 
ATOM 6038 O OD1 . ASN E 3 104 ? 135.706 112.645 155.985 1.00 86.92  ? 107 ASN E OD1 1 
ATOM 6039 N ND2 . ASN E 3 104 ? 135.876 113.782 157.906 1.00 86.92  ? 107 ASN E ND2 1 
ATOM 6040 N N   . ASP E 3 105 ? 133.597 110.132 156.222 1.00 110.39 ? 108 ASP E N   1 
ATOM 6041 C CA  . ASP E 3 105 ? 132.139 110.097 156.227 1.00 110.39 ? 108 ASP E CA  1 
ATOM 6042 C C   . ASP E 3 105 ? 131.622 108.843 156.918 1.00 110.39 ? 108 ASP E C   1 
ATOM 6043 O O   . ASP E 3 105 ? 130.642 108.894 157.671 1.00 110.39 ? 108 ASP E O   1 
ATOM 6044 C CB  . ASP E 3 105 ? 131.609 110.180 154.798 1.00 110.39 ? 108 ASP E CB  1 
ATOM 6045 C CG  . ASP E 3 105 ? 130.152 109.784 154.697 1.00 110.39 ? 108 ASP E CG  1 
ATOM 6046 O OD1 . ASP E 3 105 ? 129.295 110.525 155.220 1.00 110.39 ? 108 ASP E OD1 1 
ATOM 6047 O OD2 . ASP E 3 105 ? 129.864 108.729 154.095 1.00 110.39 ? 108 ASP E OD2 1 
ATOM 6048 N N   . ASN E 3 106 ? 132.262 107.706 156.672 1.00 121.29 ? 109 ASN E N   1 
ATOM 6049 C CA  . ASN E 3 106 ? 131.873 106.439 157.276 1.00 121.29 ? 109 ASN E CA  1 
ATOM 6050 C C   . ASN E 3 106 ? 132.867 106.090 158.375 1.00 121.29 ? 109 ASN E C   1 
ATOM 6051 O O   . ASN E 3 106 ? 134.082 106.129 158.154 1.00 121.29 ? 109 ASN E O   1 
ATOM 6052 C CB  . ASN E 3 106 ? 131.813 105.328 156.230 1.00 121.29 ? 109 ASN E CB  1 
ATOM 6053 C CG  . ASN E 3 106 ? 130.744 105.568 155.187 1.00 121.29 ? 109 ASN E CG  1 
ATOM 6054 O OD1 . ASN E 3 106 ? 129.588 105.188 155.369 1.00 121.29 ? 109 ASN E OD1 1 
ATOM 6055 N ND2 . ASN E 3 106 ? 131.124 106.204 154.086 1.00 121.29 ? 109 ASN E ND2 1 
ATOM 6056 N N   . ILE E 3 107 ? 132.352 105.756 159.553 1.00 126.10 ? 110 ILE E N   1 
ATOM 6057 C CA  . ILE E 3 107 ? 133.169 105.371 160.695 1.00 126.10 ? 110 ILE E CA  1 
ATOM 6058 C C   . ILE E 3 107 ? 132.881 103.911 161.007 1.00 126.10 ? 110 ILE E C   1 
ATOM 6059 O O   . ILE E 3 107 ? 131.718 103.519 161.150 1.00 126.10 ? 110 ILE E O   1 
ATOM 6060 C CB  . ILE E 3 107 ? 132.882 106.260 161.913 1.00 126.10 ? 110 ILE E CB  1 
ATOM 6061 C CG1 . ILE E 3 107 ? 133.393 107.681 161.667 1.00 126.10 ? 110 ILE E CG1 1 
ATOM 6062 C CG2 . ILE E 3 107 ? 133.492 105.655 163.162 1.00 126.10 ? 110 ILE E CG2 1 
ATOM 6063 C CD1 . ILE E 3 107 ? 133.064 108.647 162.783 1.00 126.10 ? 110 ILE E CD1 1 
ATOM 6064 N N   . ILE E 3 108 ? 133.931 103.100 161.104 1.00 128.48 ? 111 ILE E N   1 
ATOM 6065 C CA  . ILE E 3 108 ? 133.802 101.682 161.414 1.00 128.48 ? 111 ILE E CA  1 
ATOM 6066 C C   . ILE E 3 108 ? 134.630 101.378 162.655 1.00 128.48 ? 111 ILE E C   1 
ATOM 6067 O O   . ILE E 3 108 ? 135.837 101.642 162.685 1.00 128.48 ? 111 ILE E O   1 
ATOM 6068 C CB  . ILE E 3 108 ? 134.231 100.800 160.227 1.00 128.48 ? 111 ILE E CB  1 
ATOM 6069 C CG1 . ILE E 3 108 ? 133.277 100.978 159.045 1.00 128.48 ? 111 ILE E CG1 1 
ATOM 6070 C CG2 . ILE E 3 108 ? 134.287 99.340  160.645 1.00 128.48 ? 111 ILE E CG2 1 
ATOM 6071 C CD1 . ILE E 3 108 ? 133.774 100.354 157.763 1.00 128.48 ? 111 ILE E CD1 1 
ATOM 6072 N N   . PHE E 3 109 ? 133.978 100.827 163.676 1.00 127.36 ? 112 PHE E N   1 
ATOM 6073 C CA  . PHE E 3 109 ? 134.656 100.473 164.916 1.00 127.36 ? 112 PHE E CA  1 
ATOM 6074 C C   . PHE E 3 109 ? 135.229 99.060  164.863 1.00 127.36 ? 112 PHE E C   1 
ATOM 6075 O O   . PHE E 3 109 ? 136.327 98.813  165.373 1.00 127.36 ? 112 PHE E O   1 
ATOM 6076 C CB  . PHE E 3 109 ? 133.694 100.615 166.100 1.00 127.36 ? 112 PHE E CB  1 
ATOM 6077 C CG  . PHE E 3 109 ? 133.389 102.038 166.468 1.00 127.36 ? 112 PHE E CG  1 
ATOM 6078 C CD1 . PHE E 3 109 ? 132.518 102.796 165.705 1.00 127.36 ? 112 PHE E CD1 1 
ATOM 6079 C CD2 . PHE E 3 109 ? 133.970 102.619 167.583 1.00 127.36 ? 112 PHE E CD2 1 
ATOM 6080 C CE1 . PHE E 3 109 ? 132.232 104.108 166.045 1.00 127.36 ? 112 PHE E CE1 1 
ATOM 6081 C CE2 . PHE E 3 109 ? 133.690 103.931 167.926 1.00 127.36 ? 112 PHE E CE2 1 
ATOM 6082 C CZ  . PHE E 3 109 ? 132.819 104.675 167.155 1.00 127.36 ? 112 PHE E CZ  1 
ATOM 6083 N N   . SER E 3 110 ? 134.501 98.127  164.254 1.00 159.38 ? 113 SER E N   1 
ATOM 6084 C CA  . SER E 3 110 ? 134.955 96.752  164.110 1.00 159.38 ? 113 SER E CA  1 
ATOM 6085 C C   . SER E 3 110 ? 134.449 96.188  162.791 1.00 159.38 ? 113 SER E C   1 
ATOM 6086 O O   . SER E 3 110 ? 133.305 96.435  162.400 1.00 159.38 ? 113 SER E O   1 
ATOM 6087 C CB  . SER E 3 110 ? 134.474 95.877  165.275 1.00 159.38 ? 113 SER E CB  1 
ATOM 6088 O OG  . SER E 3 110 ? 133.059 95.849  165.341 1.00 159.38 ? 113 SER E OG  1 
ATOM 6089 N N   . GLU E 3 111 ? 135.310 95.429  162.108 1.00 178.76 ? 114 GLU E N   1 
ATOM 6090 C CA  . GLU E 3 111 ? 134.923 94.816  160.843 1.00 178.76 ? 114 GLU E CA  1 
ATOM 6091 C C   . GLU E 3 111 ? 134.009 93.612  161.033 1.00 178.76 ? 114 GLU E C   1 
ATOM 6092 O O   . GLU E 3 111 ? 133.333 93.209  160.081 1.00 178.76 ? 114 GLU E O   1 
ATOM 6093 C CB  . GLU E 3 111 ? 136.167 94.404  160.054 1.00 178.76 ? 114 GLU E CB  1 
ATOM 6094 C CG  . GLU E 3 111 ? 136.996 95.572  159.541 1.00 178.76 ? 114 GLU E CG  1 
ATOM 6095 C CD  . GLU E 3 111 ? 136.309 96.329  158.419 1.00 178.76 ? 114 GLU E CD  1 
ATOM 6096 O OE1 . GLU E 3 111 ? 135.392 95.762  157.789 1.00 178.76 ? 114 GLU E OE1 1 
ATOM 6097 O OE2 . GLU E 3 111 ? 136.687 97.492  158.168 1.00 178.76 ? 114 GLU E OE2 1 
ATOM 6098 N N   . GLU E 3 112 ? 133.978 93.030  162.229 1.00 177.99 ? 115 GLU E N   1 
ATOM 6099 C CA  . GLU E 3 112 ? 133.125 91.878  162.482 1.00 177.99 ? 115 GLU E CA  1 
ATOM 6100 C C   . GLU E 3 112 ? 131.653 92.270  162.423 1.00 177.99 ? 115 GLU E C   1 
ATOM 6101 O O   . GLU E 3 112 ? 131.262 93.375  162.810 1.00 177.99 ? 115 GLU E O   1 
ATOM 6102 C CB  . GLU E 3 112 ? 133.449 91.262  163.843 1.00 177.99 ? 115 GLU E CB  1 
ATOM 6103 C CG  . GLU E 3 112 ? 134.851 90.676  163.946 1.00 177.99 ? 115 GLU E CG  1 
ATOM 6104 C CD  . GLU E 3 112 ? 135.029 89.425  163.106 1.00 177.99 ? 115 GLU E CD  1 
ATOM 6105 O OE1 . GLU E 3 112 ? 134.013 88.780  162.768 1.00 177.99 ? 115 GLU E OE1 1 
ATOM 6106 O OE2 . GLU E 3 112 ? 136.187 89.084  162.784 1.00 177.99 ? 115 GLU E OE2 1 
ATOM 6107 N N   . TYR E 3 113 ? 130.834 91.347  161.930 1.00 168.92 ? 116 TYR E N   1 
ATOM 6108 C CA  . TYR E 3 113 ? 129.400 91.581  161.798 1.00 168.92 ? 116 TYR E CA  1 
ATOM 6109 C C   . TYR E 3 113 ? 128.728 91.675  163.164 1.00 168.92 ? 116 TYR E C   1 
ATOM 6110 O O   . TYR E 3 113 ? 127.646 92.247  163.300 0.00 168.92 ? 116 TYR E O   1 
ATOM 6111 C CB  . TYR E 3 113 ? 128.749 90.470  160.969 1.00 168.92 ? 116 TYR E CB  1 
ATOM 6112 C CG  . TYR E 3 113 ? 129.357 90.290  159.596 1.00 168.92 ? 116 TYR E CG  1 
ATOM 6113 C CD1 . TYR E 3 113 ? 128.919 91.046  158.516 1.00 168.92 ? 116 TYR E CD1 1 
ATOM 6114 C CD2 . TYR E 3 113 ? 130.367 89.362  159.379 1.00 168.92 ? 116 TYR E CD2 1 
ATOM 6115 C CE1 . TYR E 3 113 ? 129.471 90.883  157.259 1.00 168.92 ? 116 TYR E CE1 1 
ATOM 6116 C CE2 . TYR E 3 113 ? 130.925 89.192  158.126 1.00 168.92 ? 116 TYR E CE2 1 
ATOM 6117 C CZ  . TYR E 3 113 ? 130.473 89.955  157.070 1.00 168.92 ? 116 TYR E CZ  1 
ATOM 6118 O OH  . TYR E 3 113 ? 131.026 89.789  155.821 1.00 168.92 ? 116 TYR E OH  1 
ATOM 6119 O OXT . TYR E 3 113 ? 129.250 91.181  164.164 0.00 168.92 ? 116 TYR E OXT 1 
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