data_9FB7
# 
_entry.id   9FB7 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FB7         pdb_00009fb7 10.2210/pdb9fb7/pdb 
WWPDB D_1292138515 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-05-21 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FB7 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              jworrall@essex.ac.uk 
_pdbx_contact_author.name_first         Jonathan 
_pdbx_contact_author.name_last          Worrall 
_pdbx_contact_author.name_mi            A.R. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1863-834X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lucic, M.'       1 0000-0002-8264-8251 
'Worrall, J.A.R.' 2 0000-0002-1863-834X 
'Hough, M.A.'     3 0000-0001-7377-6713 
'Strange, R.W.'   4 0000-0001-8825-3608 
'Owen, R.L.'      5 0000-0002-2104-7057 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Dye-decolourising peroxidase DtpB (280 kGy)' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lucic, M.'       1 0000-0002-8264-8251 
primary 'Worrall, J.A.R.' 2 0000-0002-1863-834X 
primary 'Hough, M.A.'     3 0000-0001-7377-6713 
primary 'Strange, R.W.'   4 0000-0001-8825-3608 
primary 'Owen, R.L.'      5 0000-0002-2104-7057 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Putative dye-decolorizing peroxidase (DyP), encapsulated subgroup' 33846.836 6  ? ? ? ? 
2 non-polymer syn 'PROTOPORPHYRIN IX CONTAINING FE'                                   616.487   6  ? ? ? ? 
3 non-polymer syn 'MAGNESIUM ION'                                                     24.305    1  ? ? ? ? 
4 non-polymer syn 'TETRAETHYLENE GLYCOL'                                              194.226   1  ? ? ? ? 
5 water       nat water                                                               18.015    73 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGGEVEEPEPQMVLSPLTSAAIFLVVTIDSGGEDTVRDLLSDVASLERAVGFRAQPDGRLSCVTGIGSEAWDRLFSGARP
AGLHPFRELDGPVHRAVATPGDLLFHIRASRLDLCFALATEIMGRLRGAVTPQDEVHGFKYFDERDMLGFVDGTENPTGA
AARRAVLVGAEDPAFAGGSYAVVQKYLHDIDAWEGLSVEAQERVIGRRKMTDVELSDDVKPADSHVALTSVTGPDGSDLE
ILRDNMPFGSVGREEFGTYFIGYARTPEVTETMLERMFLGTASAPHDRILDFSTAVTGSLFFTPAADFLEDLS
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGGEVEEPEPQMVLSPLTSAAIFLVVTIDSGGEDTVRDLLSDVASLERAVGFRAQPDGRLSCVTGIGSEAWDRLFSGARP
AGLHPFRELDGPVHRAVATPGDLLFHIRASRLDLCFALATEIMGRLRGAVTPQDEVHGFKYFDERDMLGFVDGTENPTGA
AARRAVLVGAEDPAFAGGSYAVVQKYLHDIDAWEGLSVEAQERVIGRRKMTDVELSDDVKPADSHVALTSVTGPDGSDLE
ILRDNMPFGSVGREEFGTYFIGYARTPEVTETMLERMFLGTASAPHDRILDFSTAVTGSLFFTPAADFLEDLS
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'PROTOPORPHYRIN IX CONTAINING FE' HEM 
3 'MAGNESIUM ION'                   MG  
4 'TETRAETHYLENE GLYCOL'            PG4 
5 water                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   GLY n 
1 4   GLU n 
1 5   VAL n 
1 6   GLU n 
1 7   GLU n 
1 8   PRO n 
1 9   GLU n 
1 10  PRO n 
1 11  GLN n 
1 12  MET n 
1 13  VAL n 
1 14  LEU n 
1 15  SER n 
1 16  PRO n 
1 17  LEU n 
1 18  THR n 
1 19  SER n 
1 20  ALA n 
1 21  ALA n 
1 22  ILE n 
1 23  PHE n 
1 24  LEU n 
1 25  VAL n 
1 26  VAL n 
1 27  THR n 
1 28  ILE n 
1 29  ASP n 
1 30  SER n 
1 31  GLY n 
1 32  GLY n 
1 33  GLU n 
1 34  ASP n 
1 35  THR n 
1 36  VAL n 
1 37  ARG n 
1 38  ASP n 
1 39  LEU n 
1 40  LEU n 
1 41  SER n 
1 42  ASP n 
1 43  VAL n 
1 44  ALA n 
1 45  SER n 
1 46  LEU n 
1 47  GLU n 
1 48  ARG n 
1 49  ALA n 
1 50  VAL n 
1 51  GLY n 
1 52  PHE n 
1 53  ARG n 
1 54  ALA n 
1 55  GLN n 
1 56  PRO n 
1 57  ASP n 
1 58  GLY n 
1 59  ARG n 
1 60  LEU n 
1 61  SER n 
1 62  CYS n 
1 63  VAL n 
1 64  THR n 
1 65  GLY n 
1 66  ILE n 
1 67  GLY n 
1 68  SER n 
1 69  GLU n 
1 70  ALA n 
1 71  TRP n 
1 72  ASP n 
1 73  ARG n 
1 74  LEU n 
1 75  PHE n 
1 76  SER n 
1 77  GLY n 
1 78  ALA n 
1 79  ARG n 
1 80  PRO n 
1 81  ALA n 
1 82  GLY n 
1 83  LEU n 
1 84  HIS n 
1 85  PRO n 
1 86  PHE n 
1 87  ARG n 
1 88  GLU n 
1 89  LEU n 
1 90  ASP n 
1 91  GLY n 
1 92  PRO n 
1 93  VAL n 
1 94  HIS n 
1 95  ARG n 
1 96  ALA n 
1 97  VAL n 
1 98  ALA n 
1 99  THR n 
1 100 PRO n 
1 101 GLY n 
1 102 ASP n 
1 103 LEU n 
1 104 LEU n 
1 105 PHE n 
1 106 HIS n 
1 107 ILE n 
1 108 ARG n 
1 109 ALA n 
1 110 SER n 
1 111 ARG n 
1 112 LEU n 
1 113 ASP n 
1 114 LEU n 
1 115 CYS n 
1 116 PHE n 
1 117 ALA n 
1 118 LEU n 
1 119 ALA n 
1 120 THR n 
1 121 GLU n 
1 122 ILE n 
1 123 MET n 
1 124 GLY n 
1 125 ARG n 
1 126 LEU n 
1 127 ARG n 
1 128 GLY n 
1 129 ALA n 
1 130 VAL n 
1 131 THR n 
1 132 PRO n 
1 133 GLN n 
1 134 ASP n 
1 135 GLU n 
1 136 VAL n 
1 137 HIS n 
1 138 GLY n 
1 139 PHE n 
1 140 LYS n 
1 141 TYR n 
1 142 PHE n 
1 143 ASP n 
1 144 GLU n 
1 145 ARG n 
1 146 ASP n 
1 147 MET n 
1 148 LEU n 
1 149 GLY n 
1 150 PHE n 
1 151 VAL n 
1 152 ASP n 
1 153 GLY n 
1 154 THR n 
1 155 GLU n 
1 156 ASN n 
1 157 PRO n 
1 158 THR n 
1 159 GLY n 
1 160 ALA n 
1 161 ALA n 
1 162 ALA n 
1 163 ARG n 
1 164 ARG n 
1 165 ALA n 
1 166 VAL n 
1 167 LEU n 
1 168 VAL n 
1 169 GLY n 
1 170 ALA n 
1 171 GLU n 
1 172 ASP n 
1 173 PRO n 
1 174 ALA n 
1 175 PHE n 
1 176 ALA n 
1 177 GLY n 
1 178 GLY n 
1 179 SER n 
1 180 TYR n 
1 181 ALA n 
1 182 VAL n 
1 183 VAL n 
1 184 GLN n 
1 185 LYS n 
1 186 TYR n 
1 187 LEU n 
1 188 HIS n 
1 189 ASP n 
1 190 ILE n 
1 191 ASP n 
1 192 ALA n 
1 193 TRP n 
1 194 GLU n 
1 195 GLY n 
1 196 LEU n 
1 197 SER n 
1 198 VAL n 
1 199 GLU n 
1 200 ALA n 
1 201 GLN n 
1 202 GLU n 
1 203 ARG n 
1 204 VAL n 
1 205 ILE n 
1 206 GLY n 
1 207 ARG n 
1 208 ARG n 
1 209 LYS n 
1 210 MET n 
1 211 THR n 
1 212 ASP n 
1 213 VAL n 
1 214 GLU n 
1 215 LEU n 
1 216 SER n 
1 217 ASP n 
1 218 ASP n 
1 219 VAL n 
1 220 LYS n 
1 221 PRO n 
1 222 ALA n 
1 223 ASP n 
1 224 SER n 
1 225 HIS n 
1 226 VAL n 
1 227 ALA n 
1 228 LEU n 
1 229 THR n 
1 230 SER n 
1 231 VAL n 
1 232 THR n 
1 233 GLY n 
1 234 PRO n 
1 235 ASP n 
1 236 GLY n 
1 237 SER n 
1 238 ASP n 
1 239 LEU n 
1 240 GLU n 
1 241 ILE n 
1 242 LEU n 
1 243 ARG n 
1 244 ASP n 
1 245 ASN n 
1 246 MET n 
1 247 PRO n 
1 248 PHE n 
1 249 GLY n 
1 250 SER n 
1 251 VAL n 
1 252 GLY n 
1 253 ARG n 
1 254 GLU n 
1 255 GLU n 
1 256 PHE n 
1 257 GLY n 
1 258 THR n 
1 259 TYR n 
1 260 PHE n 
1 261 ILE n 
1 262 GLY n 
1 263 TYR n 
1 264 ALA n 
1 265 ARG n 
1 266 THR n 
1 267 PRO n 
1 268 GLU n 
1 269 VAL n 
1 270 THR n 
1 271 GLU n 
1 272 THR n 
1 273 MET n 
1 274 LEU n 
1 275 GLU n 
1 276 ARG n 
1 277 MET n 
1 278 PHE n 
1 279 LEU n 
1 280 GLY n 
1 281 THR n 
1 282 ALA n 
1 283 SER n 
1 284 ALA n 
1 285 PRO n 
1 286 HIS n 
1 287 ASP n 
1 288 ARG n 
1 289 ILE n 
1 290 LEU n 
1 291 ASP n 
1 292 PHE n 
1 293 SER n 
1 294 THR n 
1 295 ALA n 
1 296 VAL n 
1 297 THR n 
1 298 GLY n 
1 299 SER n 
1 300 LEU n 
1 301 PHE n 
1 302 PHE n 
1 303 THR n 
1 304 PRO n 
1 305 ALA n 
1 306 ALA n 
1 307 ASP n 
1 308 PHE n 
1 309 LEU n 
1 310 GLU n 
1 311 ASP n 
1 312 LEU n 
1 313 SER n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   313 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SLI_7409 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Streptomyces lividans 1326' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1200984 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ?    'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                          ?    'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ?    'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ?    'C4 H7 N O4'       133.103 
CYS 'L-peptide linking' y CYSTEINE                          ?    'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE                         ?    'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ?    'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                           ?    'C2 H5 N O2'       75.067  
HEM non-polymer         . 'PROTOPORPHYRIN IX CONTAINING FE' HEME 'C34 H32 Fe N4 O4' 616.487 
HIS 'L-peptide linking' y HISTIDINE                         ?    'C6 H10 N3 O2 1'   156.162 
HOH non-polymer         . WATER                             ?    'H2 O'             18.015  
ILE 'L-peptide linking' y ISOLEUCINE                        ?    'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                           ?    'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                            ?    'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                        ?    'C5 H11 N O2 S'    149.211 
MG  non-polymer         . 'MAGNESIUM ION'                   ?    'Mg 2'             24.305  
PG4 non-polymer         . 'TETRAETHYLENE GLYCOL'            ?    'C8 H18 O5'        194.226 
PHE 'L-peptide linking' y PHENYLALANINE                     ?    'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                           ?    'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                            ?    'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                         ?    'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ?    'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                          ?    'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                            ?    'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLY 2   2   ?   ?   ?   A . n 
A 1 3   GLY 3   3   ?   ?   ?   A . n 
A 1 4   GLU 4   4   ?   ?   ?   A . n 
A 1 5   VAL 5   5   ?   ?   ?   A . n 
A 1 6   GLU 6   6   ?   ?   ?   A . n 
A 1 7   GLU 7   7   ?   ?   ?   A . n 
A 1 8   PRO 8   8   8   PRO PRO A . n 
A 1 9   GLU 9   9   9   GLU GLU A . n 
A 1 10  PRO 10  10  10  PRO PRO A . n 
A 1 11  GLN 11  11  11  GLN GLN A . n 
A 1 12  MET 12  12  12  MET MET A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  LEU 14  14  14  LEU LEU A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  PRO 16  16  16  PRO PRO A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  THR 18  18  18  THR THR A . n 
A 1 19  SER 19  19  19  SER SER A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  ILE 22  22  22  ILE ILE A . n 
A 1 23  PHE 23  23  23  PHE PHE A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  VAL 25  25  25  VAL VAL A . n 
A 1 26  VAL 26  26  26  VAL VAL A . n 
A 1 27  THR 27  27  27  THR THR A . n 
A 1 28  ILE 28  28  28  ILE ILE A . n 
A 1 29  ASP 29  29  29  ASP ASP A . n 
A 1 30  SER 30  30  30  SER SER A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  GLU 33  33  33  GLU GLU A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  ARG 37  37  37  ARG ARG A . n 
A 1 38  ASP 38  38  38  ASP ASP A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  LEU 40  40  40  LEU LEU A . n 
A 1 41  SER 41  41  41  SER SER A . n 
A 1 42  ASP 42  42  42  ASP ASP A . n 
A 1 43  VAL 43  43  43  VAL VAL A . n 
A 1 44  ALA 44  44  44  ALA ALA A . n 
A 1 45  SER 45  45  45  SER SER A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  GLU 47  47  47  GLU GLU A . n 
A 1 48  ARG 48  48  48  ARG ARG A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  VAL 50  50  50  VAL VAL A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  PHE 52  52  52  PHE PHE A . n 
A 1 53  ARG 53  53  53  ARG ARG A . n 
A 1 54  ALA 54  54  54  ALA ALA A . n 
A 1 55  GLN 55  55  55  GLN GLN A . n 
A 1 56  PRO 56  56  56  PRO PRO A . n 
A 1 57  ASP 57  57  57  ASP ASP A . n 
A 1 58  GLY 58  58  58  GLY GLY A . n 
A 1 59  ARG 59  59  59  ARG ARG A . n 
A 1 60  LEU 60  60  60  LEU LEU A . n 
A 1 61  SER 61  61  61  SER SER A . n 
A 1 62  CYS 62  62  62  CYS CYS A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  THR 64  64  64  THR THR A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  ILE 66  66  66  ILE ILE A . n 
A 1 67  GLY 67  67  67  GLY GLY A . n 
A 1 68  SER 68  68  68  SER SER A . n 
A 1 69  GLU 69  69  69  GLU GLU A . n 
A 1 70  ALA 70  70  70  ALA ALA A . n 
A 1 71  TRP 71  71  71  TRP TRP A . n 
A 1 72  ASP 72  72  72  ASP ASP A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  PHE 75  75  75  PHE PHE A . n 
A 1 76  SER 76  76  76  SER SER A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  ALA 78  78  78  ALA ALA A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  PRO 80  80  80  PRO PRO A . n 
A 1 81  ALA 81  81  81  ALA ALA A . n 
A 1 82  GLY 82  82  82  GLY GLY A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  HIS 84  84  84  HIS HIS A . n 
A 1 85  PRO 85  85  85  PRO PRO A . n 
A 1 86  PHE 86  86  86  PHE PHE A . n 
A 1 87  ARG 87  87  87  ARG ARG A . n 
A 1 88  GLU 88  88  88  GLU GLU A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  ASP 90  90  90  ASP ASP A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  PRO 92  92  92  PRO PRO A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  HIS 94  94  94  HIS HIS A . n 
A 1 95  ARG 95  95  95  ARG ARG A . n 
A 1 96  ALA 96  96  96  ALA ALA A . n 
A 1 97  VAL 97  97  97  VAL VAL A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  THR 99  99  99  THR THR A . n 
A 1 100 PRO 100 100 100 PRO PRO A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 ASP 102 102 102 ASP ASP A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 PHE 105 105 105 PHE PHE A . n 
A 1 106 HIS 106 106 106 HIS HIS A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 ARG 108 108 108 ARG ARG A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 SER 110 110 110 SER SER A . n 
A 1 111 ARG 111 111 111 ARG ARG A . n 
A 1 112 LEU 112 112 112 LEU LEU A . n 
A 1 113 ASP 113 113 113 ASP ASP A . n 
A 1 114 LEU 114 114 114 LEU LEU A . n 
A 1 115 CYS 115 115 115 CYS CYS A . n 
A 1 116 PHE 116 116 116 PHE PHE A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 GLU 121 121 121 GLU GLU A . n 
A 1 122 ILE 122 122 122 ILE ILE A . n 
A 1 123 MET 123 123 123 MET MET A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 ARG 125 125 125 ARG ARG A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 ARG 127 127 127 ARG ARG A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 THR 131 131 131 THR THR A . n 
A 1 132 PRO 132 132 132 PRO PRO A . n 
A 1 133 GLN 133 133 133 GLN GLN A . n 
A 1 134 ASP 134 134 134 ASP ASP A . n 
A 1 135 GLU 135 135 135 GLU GLU A . n 
A 1 136 VAL 136 136 136 VAL VAL A . n 
A 1 137 HIS 137 137 137 HIS HIS A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 PHE 139 139 139 PHE PHE A . n 
A 1 140 LYS 140 140 140 LYS LYS A . n 
A 1 141 TYR 141 141 141 TYR TYR A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 GLU 144 144 144 GLU GLU A . n 
A 1 145 ARG 145 145 145 ARG ARG A . n 
A 1 146 ASP 146 146 146 ASP ASP A . n 
A 1 147 MET 147 147 147 MET MET A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 GLY 149 149 149 GLY GLY A . n 
A 1 150 PHE 150 150 150 PHE PHE A . n 
A 1 151 VAL 151 151 151 VAL VAL A . n 
A 1 152 ASP 152 152 152 ASP ASP A . n 
A 1 153 GLY 153 153 153 GLY GLY A . n 
A 1 154 THR 154 154 154 THR THR A . n 
A 1 155 GLU 155 155 155 GLU GLU A . n 
A 1 156 ASN 156 156 156 ASN ASN A . n 
A 1 157 PRO 157 157 157 PRO PRO A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 GLY 159 159 159 GLY GLY A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 ALA 162 162 162 ALA ALA A . n 
A 1 163 ARG 163 163 163 ARG ARG A . n 
A 1 164 ARG 164 164 164 ARG ARG A . n 
A 1 165 ALA 165 165 165 ALA ALA A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 VAL 168 168 168 VAL VAL A . n 
A 1 169 GLY 169 169 169 GLY GLY A . n 
A 1 170 ALA 170 170 170 ALA ALA A . n 
A 1 171 GLU 171 171 171 GLU GLU A . n 
A 1 172 ASP 172 172 172 ASP ASP A . n 
A 1 173 PRO 173 173 173 PRO PRO A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 PHE 175 175 175 PHE PHE A . n 
A 1 176 ALA 176 176 176 ALA ALA A . n 
A 1 177 GLY 177 177 177 GLY GLY A . n 
A 1 178 GLY 178 178 178 GLY GLY A . n 
A 1 179 SER 179 179 179 SER SER A . n 
A 1 180 TYR 180 180 180 TYR TYR A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 VAL 182 182 182 VAL VAL A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 GLN 184 184 184 GLN GLN A . n 
A 1 185 LYS 185 185 185 LYS LYS A . n 
A 1 186 TYR 186 186 186 TYR TYR A . n 
A 1 187 LEU 187 187 187 LEU LEU A . n 
A 1 188 HIS 188 188 188 HIS HIS A . n 
A 1 189 ASP 189 189 189 ASP ASP A . n 
A 1 190 ILE 190 190 190 ILE ILE A . n 
A 1 191 ASP 191 191 191 ASP ASP A . n 
A 1 192 ALA 192 192 192 ALA ALA A . n 
A 1 193 TRP 193 193 193 TRP TRP A . n 
A 1 194 GLU 194 194 194 GLU GLU A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 LEU 196 196 196 LEU LEU A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 VAL 198 198 198 VAL VAL A . n 
A 1 199 GLU 199 199 199 GLU GLU A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 GLN 201 201 201 GLN GLN A . n 
A 1 202 GLU 202 202 202 GLU GLU A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 ILE 205 205 205 ILE ILE A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 ARG 207 207 207 ARG ARG A . n 
A 1 208 ARG 208 208 208 ARG ARG A . n 
A 1 209 LYS 209 209 209 LYS LYS A . n 
A 1 210 MET 210 210 210 MET MET A . n 
A 1 211 THR 211 211 211 THR THR A . n 
A 1 212 ASP 212 212 212 ASP ASP A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 GLU 214 214 214 GLU GLU A . n 
A 1 215 LEU 215 215 215 LEU LEU A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 ASP 218 218 218 ASP ASP A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 LYS 220 220 220 LYS LYS A . n 
A 1 221 PRO 221 221 221 PRO PRO A . n 
A 1 222 ALA 222 222 222 ALA ALA A . n 
A 1 223 ASP 223 223 223 ASP ASP A . n 
A 1 224 SER 224 224 224 SER SER A . n 
A 1 225 HIS 225 225 225 HIS HIS A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 ALA 227 227 227 ALA ALA A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 THR 229 229 229 THR THR A . n 
A 1 230 SER 230 230 230 SER SER A . n 
A 1 231 VAL 231 231 231 VAL VAL A . n 
A 1 232 THR 232 232 232 THR THR A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 PRO 234 234 234 PRO PRO A . n 
A 1 235 ASP 235 235 235 ASP ASP A . n 
A 1 236 GLY 236 236 236 GLY GLY A . n 
A 1 237 SER 237 237 237 SER SER A . n 
A 1 238 ASP 238 238 238 ASP ASP A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 GLU 240 240 240 GLU GLU A . n 
A 1 241 ILE 241 241 241 ILE ILE A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 ARG 243 243 243 ARG ARG A . n 
A 1 244 ASP 244 244 244 ASP ASP A . n 
A 1 245 ASN 245 245 245 ASN ASN A . n 
A 1 246 MET 246 246 246 MET MET A . n 
A 1 247 PRO 247 247 247 PRO PRO A . n 
A 1 248 PHE 248 248 248 PHE PHE A . n 
A 1 249 GLY 249 249 249 GLY GLY A . n 
A 1 250 SER 250 250 250 SER SER A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 GLY 252 252 252 GLY GLY A . n 
A 1 253 ARG 253 253 253 ARG ARG A . n 
A 1 254 GLU 254 254 254 GLU GLU A . n 
A 1 255 GLU 255 255 255 GLU GLU A . n 
A 1 256 PHE 256 256 256 PHE PHE A . n 
A 1 257 GLY 257 257 257 GLY GLY A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 TYR 259 259 259 TYR TYR A . n 
A 1 260 PHE 260 260 260 PHE PHE A . n 
A 1 261 ILE 261 261 261 ILE ILE A . n 
A 1 262 GLY 262 262 262 GLY GLY A . n 
A 1 263 TYR 263 263 263 TYR TYR A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 ARG 265 265 265 ARG ARG A . n 
A 1 266 THR 266 266 266 THR THR A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 GLU 268 268 268 GLU GLU A . n 
A 1 269 VAL 269 269 269 VAL VAL A . n 
A 1 270 THR 270 270 270 THR THR A . n 
A 1 271 GLU 271 271 271 GLU GLU A . n 
A 1 272 THR 272 272 272 THR THR A . n 
A 1 273 MET 273 273 273 MET MET A . n 
A 1 274 LEU 274 274 274 LEU LEU A . n 
A 1 275 GLU 275 275 275 GLU GLU A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 MET 277 277 277 MET MET A . n 
A 1 278 PHE 278 278 278 PHE PHE A . n 
A 1 279 LEU 279 279 279 LEU LEU A . n 
A 1 280 GLY 280 280 280 GLY GLY A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 SER 283 283 283 SER SER A . n 
A 1 284 ALA 284 284 284 ALA ALA A . n 
A 1 285 PRO 285 285 285 PRO PRO A . n 
A 1 286 HIS 286 286 286 HIS HIS A . n 
A 1 287 ASP 287 287 287 ASP ASP A . n 
A 1 288 ARG 288 288 288 ARG ARG A . n 
A 1 289 ILE 289 289 289 ILE ILE A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 ASP 291 291 291 ASP ASP A . n 
A 1 292 PHE 292 292 292 PHE PHE A . n 
A 1 293 SER 293 293 293 SER SER A . n 
A 1 294 THR 294 294 294 THR THR A . n 
A 1 295 ALA 295 295 295 ALA ALA A . n 
A 1 296 VAL 296 296 296 VAL VAL A . n 
A 1 297 THR 297 297 297 THR THR A . n 
A 1 298 GLY 298 298 298 GLY GLY A . n 
A 1 299 SER 299 299 299 SER SER A . n 
A 1 300 LEU 300 300 300 LEU LEU A . n 
A 1 301 PHE 301 301 301 PHE PHE A . n 
A 1 302 PHE 302 302 302 PHE PHE A . n 
A 1 303 THR 303 303 303 THR THR A . n 
A 1 304 PRO 304 304 304 PRO PRO A . n 
A 1 305 ALA 305 305 305 ALA ALA A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 PHE 308 308 308 PHE PHE A . n 
A 1 309 LEU 309 309 309 LEU LEU A . n 
A 1 310 GLU 310 310 310 GLU GLU A . n 
A 1 311 ASP 311 311 311 ASP ASP A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 SER 313 313 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   GLY 2   2   ?   ?   ?   B . n 
B 1 3   GLY 3   3   ?   ?   ?   B . n 
B 1 4   GLU 4   4   ?   ?   ?   B . n 
B 1 5   VAL 5   5   ?   ?   ?   B . n 
B 1 6   GLU 6   6   ?   ?   ?   B . n 
B 1 7   GLU 7   7   7   GLU GLU B . n 
B 1 8   PRO 8   8   8   PRO PRO B . n 
B 1 9   GLU 9   9   9   GLU GLU B . n 
B 1 10  PRO 10  10  10  PRO PRO B . n 
B 1 11  GLN 11  11  11  GLN GLN B . n 
B 1 12  MET 12  12  12  MET MET B . n 
B 1 13  VAL 13  13  13  VAL VAL B . n 
B 1 14  LEU 14  14  14  LEU LEU B . n 
B 1 15  SER 15  15  15  SER SER B . n 
B 1 16  PRO 16  16  16  PRO PRO B . n 
B 1 17  LEU 17  17  17  LEU LEU B . n 
B 1 18  THR 18  18  18  THR THR B . n 
B 1 19  SER 19  19  19  SER SER B . n 
B 1 20  ALA 20  20  20  ALA ALA B . n 
B 1 21  ALA 21  21  21  ALA ALA B . n 
B 1 22  ILE 22  22  22  ILE ILE B . n 
B 1 23  PHE 23  23  23  PHE PHE B . n 
B 1 24  LEU 24  24  24  LEU LEU B . n 
B 1 25  VAL 25  25  25  VAL VAL B . n 
B 1 26  VAL 26  26  26  VAL VAL B . n 
B 1 27  THR 27  27  27  THR THR B . n 
B 1 28  ILE 28  28  28  ILE ILE B . n 
B 1 29  ASP 29  29  29  ASP ASP B . n 
B 1 30  SER 30  30  30  SER SER B . n 
B 1 31  GLY 31  31  31  GLY GLY B . n 
B 1 32  GLY 32  32  32  GLY GLY B . n 
B 1 33  GLU 33  33  33  GLU GLU B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  THR 35  35  35  THR THR B . n 
B 1 36  VAL 36  36  36  VAL VAL B . n 
B 1 37  ARG 37  37  37  ARG ARG B . n 
B 1 38  ASP 38  38  38  ASP ASP B . n 
B 1 39  LEU 39  39  39  LEU LEU B . n 
B 1 40  LEU 40  40  40  LEU LEU B . n 
B 1 41  SER 41  41  41  SER SER B . n 
B 1 42  ASP 42  42  42  ASP ASP B . n 
B 1 43  VAL 43  43  43  VAL VAL B . n 
B 1 44  ALA 44  44  44  ALA ALA B . n 
B 1 45  SER 45  45  45  SER SER B . n 
B 1 46  LEU 46  46  46  LEU LEU B . n 
B 1 47  GLU 47  47  47  GLU GLU B . n 
B 1 48  ARG 48  48  48  ARG ARG B . n 
B 1 49  ALA 49  49  49  ALA ALA B . n 
B 1 50  VAL 50  50  50  VAL VAL B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  PHE 52  52  52  PHE PHE B . n 
B 1 53  ARG 53  53  53  ARG ARG B . n 
B 1 54  ALA 54  54  54  ALA ALA B . n 
B 1 55  GLN 55  55  55  GLN GLN B . n 
B 1 56  PRO 56  56  56  PRO PRO B . n 
B 1 57  ASP 57  57  57  ASP ASP B . n 
B 1 58  GLY 58  58  58  GLY GLY B . n 
B 1 59  ARG 59  59  59  ARG ARG B . n 
B 1 60  LEU 60  60  60  LEU LEU B . n 
B 1 61  SER 61  61  61  SER SER B . n 
B 1 62  CYS 62  62  62  CYS CYS B . n 
B 1 63  VAL 63  63  63  VAL VAL B . n 
B 1 64  THR 64  64  64  THR THR B . n 
B 1 65  GLY 65  65  65  GLY GLY B . n 
B 1 66  ILE 66  66  66  ILE ILE B . n 
B 1 67  GLY 67  67  67  GLY GLY B . n 
B 1 68  SER 68  68  68  SER SER B . n 
B 1 69  GLU 69  69  69  GLU GLU B . n 
B 1 70  ALA 70  70  70  ALA ALA B . n 
B 1 71  TRP 71  71  71  TRP TRP B . n 
B 1 72  ASP 72  72  72  ASP ASP B . n 
B 1 73  ARG 73  73  73  ARG ARG B . n 
B 1 74  LEU 74  74  74  LEU LEU B . n 
B 1 75  PHE 75  75  75  PHE PHE B . n 
B 1 76  SER 76  76  76  SER SER B . n 
B 1 77  GLY 77  77  77  GLY GLY B . n 
B 1 78  ALA 78  78  78  ALA ALA B . n 
B 1 79  ARG 79  79  79  ARG ARG B . n 
B 1 80  PRO 80  80  80  PRO PRO B . n 
B 1 81  ALA 81  81  81  ALA ALA B . n 
B 1 82  GLY 82  82  82  GLY GLY B . n 
B 1 83  LEU 83  83  83  LEU LEU B . n 
B 1 84  HIS 84  84  84  HIS HIS B . n 
B 1 85  PRO 85  85  85  PRO PRO B . n 
B 1 86  PHE 86  86  86  PHE PHE B . n 
B 1 87  ARG 87  87  87  ARG ARG B . n 
B 1 88  GLU 88  88  88  GLU GLU B . n 
B 1 89  LEU 89  89  89  LEU LEU B . n 
B 1 90  ASP 90  90  90  ASP ASP B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  PRO 92  92  92  PRO PRO B . n 
B 1 93  VAL 93  93  93  VAL VAL B . n 
B 1 94  HIS 94  94  94  HIS HIS B . n 
B 1 95  ARG 95  95  95  ARG ARG B . n 
B 1 96  ALA 96  96  96  ALA ALA B . n 
B 1 97  VAL 97  97  97  VAL VAL B . n 
B 1 98  ALA 98  98  98  ALA ALA B . n 
B 1 99  THR 99  99  99  THR THR B . n 
B 1 100 PRO 100 100 100 PRO PRO B . n 
B 1 101 GLY 101 101 101 GLY GLY B . n 
B 1 102 ASP 102 102 102 ASP ASP B . n 
B 1 103 LEU 103 103 103 LEU LEU B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 PHE 105 105 105 PHE PHE B . n 
B 1 106 HIS 106 106 106 HIS HIS B . n 
B 1 107 ILE 107 107 107 ILE ILE B . n 
B 1 108 ARG 108 108 108 ARG ARG B . n 
B 1 109 ALA 109 109 109 ALA ALA B . n 
B 1 110 SER 110 110 110 SER SER B . n 
B 1 111 ARG 111 111 111 ARG ARG B . n 
B 1 112 LEU 112 112 112 LEU LEU B . n 
B 1 113 ASP 113 113 113 ASP ASP B . n 
B 1 114 LEU 114 114 114 LEU LEU B . n 
B 1 115 CYS 115 115 115 CYS CYS B . n 
B 1 116 PHE 116 116 116 PHE PHE B . n 
B 1 117 ALA 117 117 117 ALA ALA B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 ALA 119 119 119 ALA ALA B . n 
B 1 120 THR 120 120 120 THR THR B . n 
B 1 121 GLU 121 121 121 GLU GLU B . n 
B 1 122 ILE 122 122 122 ILE ILE B . n 
B 1 123 MET 123 123 123 MET MET B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 ARG 125 125 125 ARG ARG B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 ARG 127 127 127 ARG ARG B . n 
B 1 128 GLY 128 128 128 GLY GLY B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 VAL 130 130 130 VAL VAL B . n 
B 1 131 THR 131 131 131 THR THR B . n 
B 1 132 PRO 132 132 132 PRO PRO B . n 
B 1 133 GLN 133 133 133 GLN GLN B . n 
B 1 134 ASP 134 134 134 ASP ASP B . n 
B 1 135 GLU 135 135 135 GLU GLU B . n 
B 1 136 VAL 136 136 136 VAL VAL B . n 
B 1 137 HIS 137 137 137 HIS HIS B . n 
B 1 138 GLY 138 138 138 GLY GLY B . n 
B 1 139 PHE 139 139 139 PHE PHE B . n 
B 1 140 LYS 140 140 140 LYS LYS B . n 
B 1 141 TYR 141 141 141 TYR TYR B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 ASP 143 143 143 ASP ASP B . n 
B 1 144 GLU 144 144 144 GLU GLU B . n 
B 1 145 ARG 145 145 145 ARG ARG B . n 
B 1 146 ASP 146 146 146 ASP ASP B . n 
B 1 147 MET 147 147 147 MET MET B . n 
B 1 148 LEU 148 148 148 LEU LEU B . n 
B 1 149 GLY 149 149 149 GLY GLY B . n 
B 1 150 PHE 150 150 150 PHE PHE B . n 
B 1 151 VAL 151 151 151 VAL VAL B . n 
B 1 152 ASP 152 152 152 ASP ASP B . n 
B 1 153 GLY 153 153 153 GLY GLY B . n 
B 1 154 THR 154 154 154 THR THR B . n 
B 1 155 GLU 155 155 155 GLU GLU B . n 
B 1 156 ASN 156 156 156 ASN ASN B . n 
B 1 157 PRO 157 157 157 PRO PRO B . n 
B 1 158 THR 158 158 158 THR THR B . n 
B 1 159 GLY 159 159 159 GLY GLY B . n 
B 1 160 ALA 160 160 160 ALA ALA B . n 
B 1 161 ALA 161 161 161 ALA ALA B . n 
B 1 162 ALA 162 162 162 ALA ALA B . n 
B 1 163 ARG 163 163 163 ARG ARG B . n 
B 1 164 ARG 164 164 164 ARG ARG B . n 
B 1 165 ALA 165 165 165 ALA ALA B . n 
B 1 166 VAL 166 166 166 VAL VAL B . n 
B 1 167 LEU 167 167 167 LEU LEU B . n 
B 1 168 VAL 168 168 168 VAL VAL B . n 
B 1 169 GLY 169 169 169 GLY GLY B . n 
B 1 170 ALA 170 170 170 ALA ALA B . n 
B 1 171 GLU 171 171 171 GLU GLU B . n 
B 1 172 ASP 172 172 172 ASP ASP B . n 
B 1 173 PRO 173 173 173 PRO PRO B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 PHE 175 175 175 PHE PHE B . n 
B 1 176 ALA 176 176 176 ALA ALA B . n 
B 1 177 GLY 177 177 177 GLY GLY B . n 
B 1 178 GLY 178 178 178 GLY GLY B . n 
B 1 179 SER 179 179 179 SER SER B . n 
B 1 180 TYR 180 180 180 TYR TYR B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 VAL 182 182 182 VAL VAL B . n 
B 1 183 VAL 183 183 183 VAL VAL B . n 
B 1 184 GLN 184 184 184 GLN GLN B . n 
B 1 185 LYS 185 185 185 LYS LYS B . n 
B 1 186 TYR 186 186 186 TYR TYR B . n 
B 1 187 LEU 187 187 187 LEU LEU B . n 
B 1 188 HIS 188 188 188 HIS HIS B . n 
B 1 189 ASP 189 189 189 ASP ASP B . n 
B 1 190 ILE 190 190 190 ILE ILE B . n 
B 1 191 ASP 191 191 191 ASP ASP B . n 
B 1 192 ALA 192 192 192 ALA ALA B . n 
B 1 193 TRP 193 193 193 TRP TRP B . n 
B 1 194 GLU 194 194 194 GLU GLU B . n 
B 1 195 GLY 195 195 195 GLY GLY B . n 
B 1 196 LEU 196 196 196 LEU LEU B . n 
B 1 197 SER 197 197 197 SER SER B . n 
B 1 198 VAL 198 198 198 VAL VAL B . n 
B 1 199 GLU 199 199 199 GLU GLU B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 GLN 201 201 201 GLN GLN B . n 
B 1 202 GLU 202 202 202 GLU GLU B . n 
B 1 203 ARG 203 203 203 ARG ARG B . n 
B 1 204 VAL 204 204 204 VAL VAL B . n 
B 1 205 ILE 205 205 205 ILE ILE B . n 
B 1 206 GLY 206 206 206 GLY GLY B . n 
B 1 207 ARG 207 207 207 ARG ARG B . n 
B 1 208 ARG 208 208 208 ARG ARG B . n 
B 1 209 LYS 209 209 209 LYS LYS B . n 
B 1 210 MET 210 210 210 MET MET B . n 
B 1 211 THR 211 211 211 THR THR B . n 
B 1 212 ASP 212 212 212 ASP ASP B . n 
B 1 213 VAL 213 213 213 VAL VAL B . n 
B 1 214 GLU 214 214 214 GLU GLU B . n 
B 1 215 LEU 215 215 215 LEU LEU B . n 
B 1 216 SER 216 216 216 SER SER B . n 
B 1 217 ASP 217 217 217 ASP ASP B . n 
B 1 218 ASP 218 218 218 ASP ASP B . n 
B 1 219 VAL 219 219 219 VAL VAL B . n 
B 1 220 LYS 220 220 220 LYS LYS B . n 
B 1 221 PRO 221 221 221 PRO PRO B . n 
B 1 222 ALA 222 222 222 ALA ALA B . n 
B 1 223 ASP 223 223 223 ASP ASP B . n 
B 1 224 SER 224 224 224 SER SER B . n 
B 1 225 HIS 225 225 225 HIS HIS B . n 
B 1 226 VAL 226 226 226 VAL VAL B . n 
B 1 227 ALA 227 227 227 ALA ALA B . n 
B 1 228 LEU 228 228 228 LEU LEU B . n 
B 1 229 THR 229 229 229 THR THR B . n 
B 1 230 SER 230 230 230 SER SER B . n 
B 1 231 VAL 231 231 231 VAL VAL B . n 
B 1 232 THR 232 232 232 THR THR B . n 
B 1 233 GLY 233 233 233 GLY GLY B . n 
B 1 234 PRO 234 234 234 PRO PRO B . n 
B 1 235 ASP 235 235 235 ASP ASP B . n 
B 1 236 GLY 236 236 236 GLY GLY B . n 
B 1 237 SER 237 237 237 SER SER B . n 
B 1 238 ASP 238 238 238 ASP ASP B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 GLU 240 240 240 GLU GLU B . n 
B 1 241 ILE 241 241 241 ILE ILE B . n 
B 1 242 LEU 242 242 242 LEU LEU B . n 
B 1 243 ARG 243 243 243 ARG ARG B . n 
B 1 244 ASP 244 244 244 ASP ASP B . n 
B 1 245 ASN 245 245 245 ASN ASN B . n 
B 1 246 MET 246 246 246 MET MET B . n 
B 1 247 PRO 247 247 247 PRO PRO B . n 
B 1 248 PHE 248 248 248 PHE PHE B . n 
B 1 249 GLY 249 249 249 GLY GLY B . n 
B 1 250 SER 250 250 250 SER SER B . n 
B 1 251 VAL 251 251 251 VAL VAL B . n 
B 1 252 GLY 252 252 252 GLY GLY B . n 
B 1 253 ARG 253 253 253 ARG ARG B . n 
B 1 254 GLU 254 254 254 GLU GLU B . n 
B 1 255 GLU 255 255 255 GLU GLU B . n 
B 1 256 PHE 256 256 256 PHE PHE B . n 
B 1 257 GLY 257 257 257 GLY GLY B . n 
B 1 258 THR 258 258 258 THR THR B . n 
B 1 259 TYR 259 259 259 TYR TYR B . n 
B 1 260 PHE 260 260 260 PHE PHE B . n 
B 1 261 ILE 261 261 261 ILE ILE B . n 
B 1 262 GLY 262 262 262 GLY GLY B . n 
B 1 263 TYR 263 263 263 TYR TYR B . n 
B 1 264 ALA 264 264 264 ALA ALA B . n 
B 1 265 ARG 265 265 265 ARG ARG B . n 
B 1 266 THR 266 266 266 THR THR B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 GLU 268 268 268 GLU GLU B . n 
B 1 269 VAL 269 269 269 VAL VAL B . n 
B 1 270 THR 270 270 270 THR THR B . n 
B 1 271 GLU 271 271 271 GLU GLU B . n 
B 1 272 THR 272 272 272 THR THR B . n 
B 1 273 MET 273 273 273 MET MET B . n 
B 1 274 LEU 274 274 274 LEU LEU B . n 
B 1 275 GLU 275 275 275 GLU GLU B . n 
B 1 276 ARG 276 276 276 ARG ARG B . n 
B 1 277 MET 277 277 277 MET MET B . n 
B 1 278 PHE 278 278 278 PHE PHE B . n 
B 1 279 LEU 279 279 279 LEU LEU B . n 
B 1 280 GLY 280 280 280 GLY GLY B . n 
B 1 281 THR 281 281 281 THR THR B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 SER 283 283 283 SER SER B . n 
B 1 284 ALA 284 284 284 ALA ALA B . n 
B 1 285 PRO 285 285 285 PRO PRO B . n 
B 1 286 HIS 286 286 286 HIS HIS B . n 
B 1 287 ASP 287 287 287 ASP ASP B . n 
B 1 288 ARG 288 288 288 ARG ARG B . n 
B 1 289 ILE 289 289 289 ILE ILE B . n 
B 1 290 LEU 290 290 290 LEU LEU B . n 
B 1 291 ASP 291 291 291 ASP ASP B . n 
B 1 292 PHE 292 292 292 PHE PHE B . n 
B 1 293 SER 293 293 293 SER SER B . n 
B 1 294 THR 294 294 294 THR THR B . n 
B 1 295 ALA 295 295 295 ALA ALA B . n 
B 1 296 VAL 296 296 296 VAL VAL B . n 
B 1 297 THR 297 297 297 THR THR B . n 
B 1 298 GLY 298 298 298 GLY GLY B . n 
B 1 299 SER 299 299 299 SER SER B . n 
B 1 300 LEU 300 300 300 LEU LEU B . n 
B 1 301 PHE 301 301 301 PHE PHE B . n 
B 1 302 PHE 302 302 302 PHE PHE B . n 
B 1 303 THR 303 303 303 THR THR B . n 
B 1 304 PRO 304 304 304 PRO PRO B . n 
B 1 305 ALA 305 305 305 ALA ALA B . n 
B 1 306 ALA 306 306 306 ALA ALA B . n 
B 1 307 ASP 307 307 307 ASP ASP B . n 
B 1 308 PHE 308 308 308 PHE PHE B . n 
B 1 309 LEU 309 309 309 LEU LEU B . n 
B 1 310 GLU 310 310 310 GLU GLU B . n 
B 1 311 ASP 311 311 311 ASP ASP B . n 
B 1 312 LEU 312 312 ?   ?   ?   B . n 
B 1 313 SER 313 313 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   GLY 2   2   ?   ?   ?   C . n 
C 1 3   GLY 3   3   ?   ?   ?   C . n 
C 1 4   GLU 4   4   ?   ?   ?   C . n 
C 1 5   VAL 5   5   ?   ?   ?   C . n 
C 1 6   GLU 6   6   ?   ?   ?   C . n 
C 1 7   GLU 7   7   7   GLU GLU C . n 
C 1 8   PRO 8   8   8   PRO PRO C . n 
C 1 9   GLU 9   9   9   GLU GLU C . n 
C 1 10  PRO 10  10  10  PRO PRO C . n 
C 1 11  GLN 11  11  11  GLN GLN C . n 
C 1 12  MET 12  12  12  MET MET C . n 
C 1 13  VAL 13  13  13  VAL VAL C . n 
C 1 14  LEU 14  14  14  LEU LEU C . n 
C 1 15  SER 15  15  15  SER SER C . n 
C 1 16  PRO 16  16  16  PRO PRO C . n 
C 1 17  LEU 17  17  17  LEU LEU C . n 
C 1 18  THR 18  18  18  THR THR C . n 
C 1 19  SER 19  19  19  SER SER C . n 
C 1 20  ALA 20  20  20  ALA ALA C . n 
C 1 21  ALA 21  21  21  ALA ALA C . n 
C 1 22  ILE 22  22  22  ILE ILE C . n 
C 1 23  PHE 23  23  23  PHE PHE C . n 
C 1 24  LEU 24  24  24  LEU LEU C . n 
C 1 25  VAL 25  25  25  VAL VAL C . n 
C 1 26  VAL 26  26  26  VAL VAL C . n 
C 1 27  THR 27  27  27  THR THR C . n 
C 1 28  ILE 28  28  28  ILE ILE C . n 
C 1 29  ASP 29  29  29  ASP ASP C . n 
C 1 30  SER 30  30  30  SER SER C . n 
C 1 31  GLY 31  31  31  GLY GLY C . n 
C 1 32  GLY 32  32  32  GLY GLY C . n 
C 1 33  GLU 33  33  33  GLU GLU C . n 
C 1 34  ASP 34  34  34  ASP ASP C . n 
C 1 35  THR 35  35  35  THR THR C . n 
C 1 36  VAL 36  36  36  VAL VAL C . n 
C 1 37  ARG 37  37  37  ARG ARG C . n 
C 1 38  ASP 38  38  38  ASP ASP C . n 
C 1 39  LEU 39  39  39  LEU LEU C . n 
C 1 40  LEU 40  40  40  LEU LEU C . n 
C 1 41  SER 41  41  41  SER SER C . n 
C 1 42  ASP 42  42  42  ASP ASP C . n 
C 1 43  VAL 43  43  43  VAL VAL C . n 
C 1 44  ALA 44  44  44  ALA ALA C . n 
C 1 45  SER 45  45  45  SER SER C . n 
C 1 46  LEU 46  46  46  LEU LEU C . n 
C 1 47  GLU 47  47  47  GLU GLU C . n 
C 1 48  ARG 48  48  48  ARG ARG C . n 
C 1 49  ALA 49  49  49  ALA ALA C . n 
C 1 50  VAL 50  50  50  VAL VAL C . n 
C 1 51  GLY 51  51  51  GLY GLY C . n 
C 1 52  PHE 52  52  52  PHE PHE C . n 
C 1 53  ARG 53  53  53  ARG ARG C . n 
C 1 54  ALA 54  54  54  ALA ALA C . n 
C 1 55  GLN 55  55  55  GLN GLN C . n 
C 1 56  PRO 56  56  56  PRO PRO C . n 
C 1 57  ASP 57  57  57  ASP ASP C . n 
C 1 58  GLY 58  58  58  GLY GLY C . n 
C 1 59  ARG 59  59  59  ARG ARG C . n 
C 1 60  LEU 60  60  60  LEU LEU C . n 
C 1 61  SER 61  61  61  SER SER C . n 
C 1 62  CYS 62  62  62  CYS CYS C . n 
C 1 63  VAL 63  63  63  VAL VAL C . n 
C 1 64  THR 64  64  64  THR THR C . n 
C 1 65  GLY 65  65  65  GLY GLY C . n 
C 1 66  ILE 66  66  66  ILE ILE C . n 
C 1 67  GLY 67  67  67  GLY GLY C . n 
C 1 68  SER 68  68  68  SER SER C . n 
C 1 69  GLU 69  69  69  GLU GLU C . n 
C 1 70  ALA 70  70  70  ALA ALA C . n 
C 1 71  TRP 71  71  71  TRP TRP C . n 
C 1 72  ASP 72  72  72  ASP ASP C . n 
C 1 73  ARG 73  73  73  ARG ARG C . n 
C 1 74  LEU 74  74  74  LEU LEU C . n 
C 1 75  PHE 75  75  75  PHE PHE C . n 
C 1 76  SER 76  76  76  SER SER C . n 
C 1 77  GLY 77  77  77  GLY GLY C . n 
C 1 78  ALA 78  78  78  ALA ALA C . n 
C 1 79  ARG 79  79  79  ARG ARG C . n 
C 1 80  PRO 80  80  80  PRO PRO C . n 
C 1 81  ALA 81  81  81  ALA ALA C . n 
C 1 82  GLY 82  82  82  GLY GLY C . n 
C 1 83  LEU 83  83  83  LEU LEU C . n 
C 1 84  HIS 84  84  84  HIS HIS C . n 
C 1 85  PRO 85  85  85  PRO PRO C . n 
C 1 86  PHE 86  86  86  PHE PHE C . n 
C 1 87  ARG 87  87  87  ARG ARG C . n 
C 1 88  GLU 88  88  88  GLU GLU C . n 
C 1 89  LEU 89  89  89  LEU LEU C . n 
C 1 90  ASP 90  90  90  ASP ASP C . n 
C 1 91  GLY 91  91  91  GLY GLY C . n 
C 1 92  PRO 92  92  92  PRO PRO C . n 
C 1 93  VAL 93  93  93  VAL VAL C . n 
C 1 94  HIS 94  94  94  HIS HIS C . n 
C 1 95  ARG 95  95  95  ARG ARG C . n 
C 1 96  ALA 96  96  96  ALA ALA C . n 
C 1 97  VAL 97  97  97  VAL VAL C . n 
C 1 98  ALA 98  98  98  ALA ALA C . n 
C 1 99  THR 99  99  99  THR THR C . n 
C 1 100 PRO 100 100 100 PRO PRO C . n 
C 1 101 GLY 101 101 101 GLY GLY C . n 
C 1 102 ASP 102 102 102 ASP ASP C . n 
C 1 103 LEU 103 103 103 LEU LEU C . n 
C 1 104 LEU 104 104 104 LEU LEU C . n 
C 1 105 PHE 105 105 105 PHE PHE C . n 
C 1 106 HIS 106 106 106 HIS HIS C . n 
C 1 107 ILE 107 107 107 ILE ILE C . n 
C 1 108 ARG 108 108 108 ARG ARG C . n 
C 1 109 ALA 109 109 109 ALA ALA C . n 
C 1 110 SER 110 110 110 SER SER C . n 
C 1 111 ARG 111 111 111 ARG ARG C . n 
C 1 112 LEU 112 112 112 LEU LEU C . n 
C 1 113 ASP 113 113 113 ASP ASP C . n 
C 1 114 LEU 114 114 114 LEU LEU C . n 
C 1 115 CYS 115 115 115 CYS CYS C . n 
C 1 116 PHE 116 116 116 PHE PHE C . n 
C 1 117 ALA 117 117 117 ALA ALA C . n 
C 1 118 LEU 118 118 118 LEU LEU C . n 
C 1 119 ALA 119 119 119 ALA ALA C . n 
C 1 120 THR 120 120 120 THR THR C . n 
C 1 121 GLU 121 121 121 GLU GLU C . n 
C 1 122 ILE 122 122 122 ILE ILE C . n 
C 1 123 MET 123 123 123 MET MET C . n 
C 1 124 GLY 124 124 124 GLY GLY C . n 
C 1 125 ARG 125 125 125 ARG ARG C . n 
C 1 126 LEU 126 126 126 LEU LEU C . n 
C 1 127 ARG 127 127 127 ARG ARG C . n 
C 1 128 GLY 128 128 128 GLY GLY C . n 
C 1 129 ALA 129 129 129 ALA ALA C . n 
C 1 130 VAL 130 130 130 VAL VAL C . n 
C 1 131 THR 131 131 131 THR THR C . n 
C 1 132 PRO 132 132 132 PRO PRO C . n 
C 1 133 GLN 133 133 133 GLN GLN C . n 
C 1 134 ASP 134 134 134 ASP ASP C . n 
C 1 135 GLU 135 135 135 GLU GLU C . n 
C 1 136 VAL 136 136 136 VAL VAL C . n 
C 1 137 HIS 137 137 137 HIS HIS C . n 
C 1 138 GLY 138 138 138 GLY GLY C . n 
C 1 139 PHE 139 139 139 PHE PHE C . n 
C 1 140 LYS 140 140 140 LYS LYS C . n 
C 1 141 TYR 141 141 141 TYR TYR C . n 
C 1 142 PHE 142 142 142 PHE PHE C . n 
C 1 143 ASP 143 143 143 ASP ASP C . n 
C 1 144 GLU 144 144 144 GLU GLU C . n 
C 1 145 ARG 145 145 145 ARG ARG C . n 
C 1 146 ASP 146 146 146 ASP ASP C . n 
C 1 147 MET 147 147 147 MET MET C . n 
C 1 148 LEU 148 148 148 LEU LEU C . n 
C 1 149 GLY 149 149 149 GLY GLY C . n 
C 1 150 PHE 150 150 150 PHE PHE C . n 
C 1 151 VAL 151 151 151 VAL VAL C . n 
C 1 152 ASP 152 152 152 ASP ASP C . n 
C 1 153 GLY 153 153 153 GLY GLY C . n 
C 1 154 THR 154 154 154 THR THR C . n 
C 1 155 GLU 155 155 155 GLU GLU C . n 
C 1 156 ASN 156 156 156 ASN ASN C . n 
C 1 157 PRO 157 157 157 PRO PRO C . n 
C 1 158 THR 158 158 158 THR THR C . n 
C 1 159 GLY 159 159 159 GLY GLY C . n 
C 1 160 ALA 160 160 160 ALA ALA C . n 
C 1 161 ALA 161 161 161 ALA ALA C . n 
C 1 162 ALA 162 162 162 ALA ALA C . n 
C 1 163 ARG 163 163 163 ARG ARG C . n 
C 1 164 ARG 164 164 164 ARG ARG C . n 
C 1 165 ALA 165 165 165 ALA ALA C . n 
C 1 166 VAL 166 166 166 VAL VAL C . n 
C 1 167 LEU 167 167 167 LEU LEU C . n 
C 1 168 VAL 168 168 168 VAL VAL C . n 
C 1 169 GLY 169 169 169 GLY GLY C . n 
C 1 170 ALA 170 170 170 ALA ALA C . n 
C 1 171 GLU 171 171 171 GLU GLU C . n 
C 1 172 ASP 172 172 172 ASP ASP C . n 
C 1 173 PRO 173 173 173 PRO PRO C . n 
C 1 174 ALA 174 174 174 ALA ALA C . n 
C 1 175 PHE 175 175 175 PHE PHE C . n 
C 1 176 ALA 176 176 176 ALA ALA C . n 
C 1 177 GLY 177 177 177 GLY GLY C . n 
C 1 178 GLY 178 178 178 GLY GLY C . n 
C 1 179 SER 179 179 179 SER SER C . n 
C 1 180 TYR 180 180 180 TYR TYR C . n 
C 1 181 ALA 181 181 181 ALA ALA C . n 
C 1 182 VAL 182 182 182 VAL VAL C . n 
C 1 183 VAL 183 183 183 VAL VAL C . n 
C 1 184 GLN 184 184 184 GLN GLN C . n 
C 1 185 LYS 185 185 185 LYS LYS C . n 
C 1 186 TYR 186 186 186 TYR TYR C . n 
C 1 187 LEU 187 187 187 LEU LEU C . n 
C 1 188 HIS 188 188 188 HIS HIS C . n 
C 1 189 ASP 189 189 189 ASP ASP C . n 
C 1 190 ILE 190 190 190 ILE ILE C . n 
C 1 191 ASP 191 191 191 ASP ASP C . n 
C 1 192 ALA 192 192 192 ALA ALA C . n 
C 1 193 TRP 193 193 193 TRP TRP C . n 
C 1 194 GLU 194 194 194 GLU GLU C . n 
C 1 195 GLY 195 195 195 GLY GLY C . n 
C 1 196 LEU 196 196 196 LEU LEU C . n 
C 1 197 SER 197 197 197 SER SER C . n 
C 1 198 VAL 198 198 198 VAL VAL C . n 
C 1 199 GLU 199 199 199 GLU GLU C . n 
C 1 200 ALA 200 200 200 ALA ALA C . n 
C 1 201 GLN 201 201 201 GLN GLN C . n 
C 1 202 GLU 202 202 202 GLU GLU C . n 
C 1 203 ARG 203 203 203 ARG ARG C . n 
C 1 204 VAL 204 204 204 VAL VAL C . n 
C 1 205 ILE 205 205 205 ILE ILE C . n 
C 1 206 GLY 206 206 206 GLY GLY C . n 
C 1 207 ARG 207 207 207 ARG ARG C . n 
C 1 208 ARG 208 208 208 ARG ARG C . n 
C 1 209 LYS 209 209 209 LYS LYS C . n 
C 1 210 MET 210 210 210 MET MET C . n 
C 1 211 THR 211 211 211 THR THR C . n 
C 1 212 ASP 212 212 212 ASP ASP C . n 
C 1 213 VAL 213 213 213 VAL VAL C . n 
C 1 214 GLU 214 214 214 GLU GLU C . n 
C 1 215 LEU 215 215 215 LEU LEU C . n 
C 1 216 SER 216 216 216 SER SER C . n 
C 1 217 ASP 217 217 217 ASP ASP C . n 
C 1 218 ASP 218 218 218 ASP ASP C . n 
C 1 219 VAL 219 219 219 VAL VAL C . n 
C 1 220 LYS 220 220 220 LYS LYS C . n 
C 1 221 PRO 221 221 221 PRO PRO C . n 
C 1 222 ALA 222 222 222 ALA ALA C . n 
C 1 223 ASP 223 223 223 ASP ASP C . n 
C 1 224 SER 224 224 224 SER SER C . n 
C 1 225 HIS 225 225 225 HIS HIS C . n 
C 1 226 VAL 226 226 226 VAL VAL C . n 
C 1 227 ALA 227 227 227 ALA ALA C . n 
C 1 228 LEU 228 228 228 LEU LEU C . n 
C 1 229 THR 229 229 229 THR THR C . n 
C 1 230 SER 230 230 230 SER SER C . n 
C 1 231 VAL 231 231 231 VAL VAL C . n 
C 1 232 THR 232 232 232 THR THR C . n 
C 1 233 GLY 233 233 233 GLY GLY C . n 
C 1 234 PRO 234 234 234 PRO PRO C . n 
C 1 235 ASP 235 235 235 ASP ASP C . n 
C 1 236 GLY 236 236 236 GLY GLY C . n 
C 1 237 SER 237 237 237 SER SER C . n 
C 1 238 ASP 238 238 238 ASP ASP C . n 
C 1 239 LEU 239 239 239 LEU LEU C . n 
C 1 240 GLU 240 240 240 GLU GLU C . n 
C 1 241 ILE 241 241 241 ILE ILE C . n 
C 1 242 LEU 242 242 242 LEU LEU C . n 
C 1 243 ARG 243 243 243 ARG ARG C . n 
C 1 244 ASP 244 244 244 ASP ASP C . n 
C 1 245 ASN 245 245 245 ASN ASN C . n 
C 1 246 MET 246 246 246 MET MET C . n 
C 1 247 PRO 247 247 247 PRO PRO C . n 
C 1 248 PHE 248 248 248 PHE PHE C . n 
C 1 249 GLY 249 249 249 GLY GLY C . n 
C 1 250 SER 250 250 250 SER SER C . n 
C 1 251 VAL 251 251 251 VAL VAL C . n 
C 1 252 GLY 252 252 252 GLY GLY C . n 
C 1 253 ARG 253 253 253 ARG ARG C . n 
C 1 254 GLU 254 254 254 GLU GLU C . n 
C 1 255 GLU 255 255 255 GLU GLU C . n 
C 1 256 PHE 256 256 256 PHE PHE C . n 
C 1 257 GLY 257 257 257 GLY GLY C . n 
C 1 258 THR 258 258 258 THR THR C . n 
C 1 259 TYR 259 259 259 TYR TYR C . n 
C 1 260 PHE 260 260 260 PHE PHE C . n 
C 1 261 ILE 261 261 261 ILE ILE C . n 
C 1 262 GLY 262 262 262 GLY GLY C . n 
C 1 263 TYR 263 263 263 TYR TYR C . n 
C 1 264 ALA 264 264 264 ALA ALA C . n 
C 1 265 ARG 265 265 265 ARG ARG C . n 
C 1 266 THR 266 266 266 THR THR C . n 
C 1 267 PRO 267 267 267 PRO PRO C . n 
C 1 268 GLU 268 268 268 GLU GLU C . n 
C 1 269 VAL 269 269 269 VAL VAL C . n 
C 1 270 THR 270 270 270 THR THR C . n 
C 1 271 GLU 271 271 271 GLU GLU C . n 
C 1 272 THR 272 272 272 THR THR C . n 
C 1 273 MET 273 273 273 MET MET C . n 
C 1 274 LEU 274 274 274 LEU LEU C . n 
C 1 275 GLU 275 275 275 GLU GLU C . n 
C 1 276 ARG 276 276 276 ARG ARG C . n 
C 1 277 MET 277 277 277 MET MET C . n 
C 1 278 PHE 278 278 278 PHE PHE C . n 
C 1 279 LEU 279 279 279 LEU LEU C . n 
C 1 280 GLY 280 280 280 GLY GLY C . n 
C 1 281 THR 281 281 281 THR THR C . n 
C 1 282 ALA 282 282 282 ALA ALA C . n 
C 1 283 SER 283 283 283 SER SER C . n 
C 1 284 ALA 284 284 284 ALA ALA C . n 
C 1 285 PRO 285 285 285 PRO PRO C . n 
C 1 286 HIS 286 286 286 HIS HIS C . n 
C 1 287 ASP 287 287 287 ASP ASP C . n 
C 1 288 ARG 288 288 288 ARG ARG C . n 
C 1 289 ILE 289 289 289 ILE ILE C . n 
C 1 290 LEU 290 290 290 LEU LEU C . n 
C 1 291 ASP 291 291 291 ASP ASP C . n 
C 1 292 PHE 292 292 292 PHE PHE C . n 
C 1 293 SER 293 293 293 SER SER C . n 
C 1 294 THR 294 294 294 THR THR C . n 
C 1 295 ALA 295 295 295 ALA ALA C . n 
C 1 296 VAL 296 296 296 VAL VAL C . n 
C 1 297 THR 297 297 297 THR THR C . n 
C 1 298 GLY 298 298 298 GLY GLY C . n 
C 1 299 SER 299 299 299 SER SER C . n 
C 1 300 LEU 300 300 300 LEU LEU C . n 
C 1 301 PHE 301 301 301 PHE PHE C . n 
C 1 302 PHE 302 302 302 PHE PHE C . n 
C 1 303 THR 303 303 303 THR THR C . n 
C 1 304 PRO 304 304 304 PRO PRO C . n 
C 1 305 ALA 305 305 305 ALA ALA C . n 
C 1 306 ALA 306 306 306 ALA ALA C . n 
C 1 307 ASP 307 307 307 ASP ASP C . n 
C 1 308 PHE 308 308 308 PHE PHE C . n 
C 1 309 LEU 309 309 309 LEU LEU C . n 
C 1 310 GLU 310 310 310 GLU GLU C . n 
C 1 311 ASP 311 311 311 ASP ASP C . n 
C 1 312 LEU 312 312 312 LEU LEU C . n 
C 1 313 SER 313 313 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   GLY 2   2   ?   ?   ?   D . n 
D 1 3   GLY 3   3   ?   ?   ?   D . n 
D 1 4   GLU 4   4   ?   ?   ?   D . n 
D 1 5   VAL 5   5   ?   ?   ?   D . n 
D 1 6   GLU 6   6   ?   ?   ?   D . n 
D 1 7   GLU 7   7   7   GLU GLU D . n 
D 1 8   PRO 8   8   8   PRO PRO D . n 
D 1 9   GLU 9   9   9   GLU GLU D . n 
D 1 10  PRO 10  10  10  PRO PRO D . n 
D 1 11  GLN 11  11  11  GLN GLN D . n 
D 1 12  MET 12  12  12  MET MET D . n 
D 1 13  VAL 13  13  13  VAL VAL D . n 
D 1 14  LEU 14  14  14  LEU LEU D . n 
D 1 15  SER 15  15  15  SER SER D . n 
D 1 16  PRO 16  16  16  PRO PRO D . n 
D 1 17  LEU 17  17  17  LEU LEU D . n 
D 1 18  THR 18  18  18  THR THR D . n 
D 1 19  SER 19  19  19  SER SER D . n 
D 1 20  ALA 20  20  20  ALA ALA D . n 
D 1 21  ALA 21  21  21  ALA ALA D . n 
D 1 22  ILE 22  22  22  ILE ILE D . n 
D 1 23  PHE 23  23  23  PHE PHE D . n 
D 1 24  LEU 24  24  24  LEU LEU D . n 
D 1 25  VAL 25  25  25  VAL VAL D . n 
D 1 26  VAL 26  26  26  VAL VAL D . n 
D 1 27  THR 27  27  27  THR THR D . n 
D 1 28  ILE 28  28  28  ILE ILE D . n 
D 1 29  ASP 29  29  29  ASP ASP D . n 
D 1 30  SER 30  30  30  SER SER D . n 
D 1 31  GLY 31  31  31  GLY GLY D . n 
D 1 32  GLY 32  32  32  GLY GLY D . n 
D 1 33  GLU 33  33  33  GLU GLU D . n 
D 1 34  ASP 34  34  34  ASP ASP D . n 
D 1 35  THR 35  35  35  THR THR D . n 
D 1 36  VAL 36  36  36  VAL VAL D . n 
D 1 37  ARG 37  37  37  ARG ARG D . n 
D 1 38  ASP 38  38  38  ASP ASP D . n 
D 1 39  LEU 39  39  39  LEU LEU D . n 
D 1 40  LEU 40  40  40  LEU LEU D . n 
D 1 41  SER 41  41  41  SER SER D . n 
D 1 42  ASP 42  42  42  ASP ASP D . n 
D 1 43  VAL 43  43  43  VAL VAL D . n 
D 1 44  ALA 44  44  44  ALA ALA D . n 
D 1 45  SER 45  45  45  SER SER D . n 
D 1 46  LEU 46  46  46  LEU LEU D . n 
D 1 47  GLU 47  47  47  GLU GLU D . n 
D 1 48  ARG 48  48  48  ARG ARG D . n 
D 1 49  ALA 49  49  49  ALA ALA D . n 
D 1 50  VAL 50  50  50  VAL VAL D . n 
D 1 51  GLY 51  51  51  GLY GLY D . n 
D 1 52  PHE 52  52  52  PHE PHE D . n 
D 1 53  ARG 53  53  53  ARG ARG D . n 
D 1 54  ALA 54  54  54  ALA ALA D . n 
D 1 55  GLN 55  55  55  GLN GLN D . n 
D 1 56  PRO 56  56  56  PRO PRO D . n 
D 1 57  ASP 57  57  57  ASP ASP D . n 
D 1 58  GLY 58  58  58  GLY GLY D . n 
D 1 59  ARG 59  59  59  ARG ARG D . n 
D 1 60  LEU 60  60  60  LEU LEU D . n 
D 1 61  SER 61  61  61  SER SER D . n 
D 1 62  CYS 62  62  62  CYS CYS D . n 
D 1 63  VAL 63  63  63  VAL VAL D . n 
D 1 64  THR 64  64  64  THR THR D . n 
D 1 65  GLY 65  65  65  GLY GLY D . n 
D 1 66  ILE 66  66  66  ILE ILE D . n 
D 1 67  GLY 67  67  67  GLY GLY D . n 
D 1 68  SER 68  68  68  SER SER D . n 
D 1 69  GLU 69  69  69  GLU GLU D . n 
D 1 70  ALA 70  70  70  ALA ALA D . n 
D 1 71  TRP 71  71  71  TRP TRP D . n 
D 1 72  ASP 72  72  72  ASP ASP D . n 
D 1 73  ARG 73  73  73  ARG ARG D . n 
D 1 74  LEU 74  74  74  LEU LEU D . n 
D 1 75  PHE 75  75  75  PHE PHE D . n 
D 1 76  SER 76  76  76  SER SER D . n 
D 1 77  GLY 77  77  77  GLY GLY D . n 
D 1 78  ALA 78  78  78  ALA ALA D . n 
D 1 79  ARG 79  79  79  ARG ARG D . n 
D 1 80  PRO 80  80  80  PRO PRO D . n 
D 1 81  ALA 81  81  81  ALA ALA D . n 
D 1 82  GLY 82  82  82  GLY GLY D . n 
D 1 83  LEU 83  83  83  LEU LEU D . n 
D 1 84  HIS 84  84  84  HIS HIS D . n 
D 1 85  PRO 85  85  85  PRO PRO D . n 
D 1 86  PHE 86  86  86  PHE PHE D . n 
D 1 87  ARG 87  87  87  ARG ARG D . n 
D 1 88  GLU 88  88  88  GLU GLU D . n 
D 1 89  LEU 89  89  89  LEU LEU D . n 
D 1 90  ASP 90  90  90  ASP ASP D . n 
D 1 91  GLY 91  91  91  GLY GLY D . n 
D 1 92  PRO 92  92  92  PRO PRO D . n 
D 1 93  VAL 93  93  93  VAL VAL D . n 
D 1 94  HIS 94  94  94  HIS HIS D . n 
D 1 95  ARG 95  95  95  ARG ARG D . n 
D 1 96  ALA 96  96  96  ALA ALA D . n 
D 1 97  VAL 97  97  97  VAL VAL D . n 
D 1 98  ALA 98  98  98  ALA ALA D . n 
D 1 99  THR 99  99  99  THR THR D . n 
D 1 100 PRO 100 100 100 PRO PRO D . n 
D 1 101 GLY 101 101 101 GLY GLY D . n 
D 1 102 ASP 102 102 102 ASP ASP D . n 
D 1 103 LEU 103 103 103 LEU LEU D . n 
D 1 104 LEU 104 104 104 LEU LEU D . n 
D 1 105 PHE 105 105 105 PHE PHE D . n 
D 1 106 HIS 106 106 106 HIS HIS D . n 
D 1 107 ILE 107 107 107 ILE ILE D . n 
D 1 108 ARG 108 108 108 ARG ARG D . n 
D 1 109 ALA 109 109 109 ALA ALA D . n 
D 1 110 SER 110 110 110 SER SER D . n 
D 1 111 ARG 111 111 111 ARG ARG D . n 
D 1 112 LEU 112 112 112 LEU LEU D . n 
D 1 113 ASP 113 113 113 ASP ASP D . n 
D 1 114 LEU 114 114 114 LEU LEU D . n 
D 1 115 CYS 115 115 115 CYS CYS D . n 
D 1 116 PHE 116 116 116 PHE PHE D . n 
D 1 117 ALA 117 117 117 ALA ALA D . n 
D 1 118 LEU 118 118 118 LEU LEU D . n 
D 1 119 ALA 119 119 119 ALA ALA D . n 
D 1 120 THR 120 120 120 THR THR D . n 
D 1 121 GLU 121 121 121 GLU GLU D . n 
D 1 122 ILE 122 122 122 ILE ILE D . n 
D 1 123 MET 123 123 123 MET MET D . n 
D 1 124 GLY 124 124 124 GLY GLY D . n 
D 1 125 ARG 125 125 125 ARG ARG D . n 
D 1 126 LEU 126 126 126 LEU LEU D . n 
D 1 127 ARG 127 127 127 ARG ARG D . n 
D 1 128 GLY 128 128 128 GLY GLY D . n 
D 1 129 ALA 129 129 129 ALA ALA D . n 
D 1 130 VAL 130 130 130 VAL VAL D . n 
D 1 131 THR 131 131 131 THR THR D . n 
D 1 132 PRO 132 132 132 PRO PRO D . n 
D 1 133 GLN 133 133 133 GLN GLN D . n 
D 1 134 ASP 134 134 134 ASP ASP D . n 
D 1 135 GLU 135 135 135 GLU GLU D . n 
D 1 136 VAL 136 136 136 VAL VAL D . n 
D 1 137 HIS 137 137 137 HIS HIS D . n 
D 1 138 GLY 138 138 138 GLY GLY D . n 
D 1 139 PHE 139 139 139 PHE PHE D . n 
D 1 140 LYS 140 140 140 LYS LYS D . n 
D 1 141 TYR 141 141 141 TYR TYR D . n 
D 1 142 PHE 142 142 142 PHE PHE D . n 
D 1 143 ASP 143 143 143 ASP ASP D . n 
D 1 144 GLU 144 144 144 GLU GLU D . n 
D 1 145 ARG 145 145 145 ARG ARG D . n 
D 1 146 ASP 146 146 146 ASP ASP D . n 
D 1 147 MET 147 147 147 MET MET D . n 
D 1 148 LEU 148 148 148 LEU LEU D . n 
D 1 149 GLY 149 149 149 GLY GLY D . n 
D 1 150 PHE 150 150 150 PHE PHE D . n 
D 1 151 VAL 151 151 151 VAL VAL D . n 
D 1 152 ASP 152 152 152 ASP ASP D . n 
D 1 153 GLY 153 153 153 GLY GLY D . n 
D 1 154 THR 154 154 154 THR THR D . n 
D 1 155 GLU 155 155 155 GLU GLU D . n 
D 1 156 ASN 156 156 156 ASN ASN D . n 
D 1 157 PRO 157 157 157 PRO PRO D . n 
D 1 158 THR 158 158 158 THR THR D . n 
D 1 159 GLY 159 159 159 GLY GLY D . n 
D 1 160 ALA 160 160 160 ALA ALA D . n 
D 1 161 ALA 161 161 161 ALA ALA D . n 
D 1 162 ALA 162 162 162 ALA ALA D . n 
D 1 163 ARG 163 163 163 ARG ARG D . n 
D 1 164 ARG 164 164 164 ARG ARG D . n 
D 1 165 ALA 165 165 165 ALA ALA D . n 
D 1 166 VAL 166 166 166 VAL VAL D . n 
D 1 167 LEU 167 167 167 LEU LEU D . n 
D 1 168 VAL 168 168 168 VAL VAL D . n 
D 1 169 GLY 169 169 169 GLY GLY D . n 
D 1 170 ALA 170 170 170 ALA ALA D . n 
D 1 171 GLU 171 171 171 GLU GLU D . n 
D 1 172 ASP 172 172 172 ASP ASP D . n 
D 1 173 PRO 173 173 173 PRO PRO D . n 
D 1 174 ALA 174 174 174 ALA ALA D . n 
D 1 175 PHE 175 175 175 PHE PHE D . n 
D 1 176 ALA 176 176 176 ALA ALA D . n 
D 1 177 GLY 177 177 177 GLY GLY D . n 
D 1 178 GLY 178 178 178 GLY GLY D . n 
D 1 179 SER 179 179 179 SER SER D . n 
D 1 180 TYR 180 180 180 TYR TYR D . n 
D 1 181 ALA 181 181 181 ALA ALA D . n 
D 1 182 VAL 182 182 182 VAL VAL D . n 
D 1 183 VAL 183 183 183 VAL VAL D . n 
D 1 184 GLN 184 184 184 GLN GLN D . n 
D 1 185 LYS 185 185 185 LYS LYS D . n 
D 1 186 TYR 186 186 186 TYR TYR D . n 
D 1 187 LEU 187 187 187 LEU LEU D . n 
D 1 188 HIS 188 188 188 HIS HIS D . n 
D 1 189 ASP 189 189 189 ASP ASP D . n 
D 1 190 ILE 190 190 190 ILE ILE D . n 
D 1 191 ASP 191 191 191 ASP ASP D . n 
D 1 192 ALA 192 192 192 ALA ALA D . n 
D 1 193 TRP 193 193 193 TRP TRP D . n 
D 1 194 GLU 194 194 194 GLU GLU D . n 
D 1 195 GLY 195 195 195 GLY GLY D . n 
D 1 196 LEU 196 196 196 LEU LEU D . n 
D 1 197 SER 197 197 197 SER SER D . n 
D 1 198 VAL 198 198 198 VAL VAL D . n 
D 1 199 GLU 199 199 199 GLU GLU D . n 
D 1 200 ALA 200 200 200 ALA ALA D . n 
D 1 201 GLN 201 201 201 GLN GLN D . n 
D 1 202 GLU 202 202 202 GLU GLU D . n 
D 1 203 ARG 203 203 203 ARG ARG D . n 
D 1 204 VAL 204 204 204 VAL VAL D . n 
D 1 205 ILE 205 205 205 ILE ILE D . n 
D 1 206 GLY 206 206 206 GLY GLY D . n 
D 1 207 ARG 207 207 207 ARG ARG D . n 
D 1 208 ARG 208 208 208 ARG ARG D . n 
D 1 209 LYS 209 209 209 LYS LYS D . n 
D 1 210 MET 210 210 210 MET MET D . n 
D 1 211 THR 211 211 211 THR THR D . n 
D 1 212 ASP 212 212 212 ASP ASP D . n 
D 1 213 VAL 213 213 213 VAL VAL D . n 
D 1 214 GLU 214 214 214 GLU GLU D . n 
D 1 215 LEU 215 215 215 LEU LEU D . n 
D 1 216 SER 216 216 216 SER SER D . n 
D 1 217 ASP 217 217 217 ASP ASP D . n 
D 1 218 ASP 218 218 218 ASP ASP D . n 
D 1 219 VAL 219 219 219 VAL VAL D . n 
D 1 220 LYS 220 220 220 LYS LYS D . n 
D 1 221 PRO 221 221 221 PRO PRO D . n 
D 1 222 ALA 222 222 222 ALA ALA D . n 
D 1 223 ASP 223 223 223 ASP ASP D . n 
D 1 224 SER 224 224 224 SER SER D . n 
D 1 225 HIS 225 225 225 HIS HIS D . n 
D 1 226 VAL 226 226 226 VAL VAL D . n 
D 1 227 ALA 227 227 227 ALA ALA D . n 
D 1 228 LEU 228 228 228 LEU LEU D . n 
D 1 229 THR 229 229 229 THR THR D . n 
D 1 230 SER 230 230 230 SER SER D . n 
D 1 231 VAL 231 231 231 VAL VAL D . n 
D 1 232 THR 232 232 232 THR THR D . n 
D 1 233 GLY 233 233 233 GLY GLY D . n 
D 1 234 PRO 234 234 234 PRO PRO D . n 
D 1 235 ASP 235 235 235 ASP ASP D . n 
D 1 236 GLY 236 236 236 GLY GLY D . n 
D 1 237 SER 237 237 237 SER SER D . n 
D 1 238 ASP 238 238 238 ASP ASP D . n 
D 1 239 LEU 239 239 239 LEU LEU D . n 
D 1 240 GLU 240 240 240 GLU GLU D . n 
D 1 241 ILE 241 241 241 ILE ILE D . n 
D 1 242 LEU 242 242 242 LEU LEU D . n 
D 1 243 ARG 243 243 243 ARG ARG D . n 
D 1 244 ASP 244 244 244 ASP ASP D . n 
D 1 245 ASN 245 245 245 ASN ASN D . n 
D 1 246 MET 246 246 246 MET MET D . n 
D 1 247 PRO 247 247 247 PRO PRO D . n 
D 1 248 PHE 248 248 248 PHE PHE D . n 
D 1 249 GLY 249 249 249 GLY GLY D . n 
D 1 250 SER 250 250 250 SER SER D . n 
D 1 251 VAL 251 251 251 VAL VAL D . n 
D 1 252 GLY 252 252 252 GLY GLY D . n 
D 1 253 ARG 253 253 253 ARG ARG D . n 
D 1 254 GLU 254 254 254 GLU GLU D . n 
D 1 255 GLU 255 255 255 GLU GLU D . n 
D 1 256 PHE 256 256 256 PHE PHE D . n 
D 1 257 GLY 257 257 257 GLY GLY D . n 
D 1 258 THR 258 258 258 THR THR D . n 
D 1 259 TYR 259 259 259 TYR TYR D . n 
D 1 260 PHE 260 260 260 PHE PHE D . n 
D 1 261 ILE 261 261 261 ILE ILE D . n 
D 1 262 GLY 262 262 262 GLY GLY D . n 
D 1 263 TYR 263 263 263 TYR TYR D . n 
D 1 264 ALA 264 264 264 ALA ALA D . n 
D 1 265 ARG 265 265 265 ARG ARG D . n 
D 1 266 THR 266 266 266 THR THR D . n 
D 1 267 PRO 267 267 267 PRO PRO D . n 
D 1 268 GLU 268 268 268 GLU GLU D . n 
D 1 269 VAL 269 269 269 VAL VAL D . n 
D 1 270 THR 270 270 270 THR THR D . n 
D 1 271 GLU 271 271 271 GLU GLU D . n 
D 1 272 THR 272 272 272 THR THR D . n 
D 1 273 MET 273 273 273 MET MET D . n 
D 1 274 LEU 274 274 274 LEU LEU D . n 
D 1 275 GLU 275 275 275 GLU GLU D . n 
D 1 276 ARG 276 276 276 ARG ARG D . n 
D 1 277 MET 277 277 277 MET MET D . n 
D 1 278 PHE 278 278 278 PHE PHE D . n 
D 1 279 LEU 279 279 279 LEU LEU D . n 
D 1 280 GLY 280 280 280 GLY GLY D . n 
D 1 281 THR 281 281 281 THR THR D . n 
D 1 282 ALA 282 282 282 ALA ALA D . n 
D 1 283 SER 283 283 283 SER SER D . n 
D 1 284 ALA 284 284 284 ALA ALA D . n 
D 1 285 PRO 285 285 285 PRO PRO D . n 
D 1 286 HIS 286 286 286 HIS HIS D . n 
D 1 287 ASP 287 287 287 ASP ASP D . n 
D 1 288 ARG 288 288 288 ARG ARG D . n 
D 1 289 ILE 289 289 289 ILE ILE D . n 
D 1 290 LEU 290 290 290 LEU LEU D . n 
D 1 291 ASP 291 291 291 ASP ASP D . n 
D 1 292 PHE 292 292 292 PHE PHE D . n 
D 1 293 SER 293 293 293 SER SER D . n 
D 1 294 THR 294 294 294 THR THR D . n 
D 1 295 ALA 295 295 295 ALA ALA D . n 
D 1 296 VAL 296 296 296 VAL VAL D . n 
D 1 297 THR 297 297 297 THR THR D . n 
D 1 298 GLY 298 298 298 GLY GLY D . n 
D 1 299 SER 299 299 299 SER SER D . n 
D 1 300 LEU 300 300 300 LEU LEU D . n 
D 1 301 PHE 301 301 301 PHE PHE D . n 
D 1 302 PHE 302 302 302 PHE PHE D . n 
D 1 303 THR 303 303 303 THR THR D . n 
D 1 304 PRO 304 304 304 PRO PRO D . n 
D 1 305 ALA 305 305 305 ALA ALA D . n 
D 1 306 ALA 306 306 306 ALA ALA D . n 
D 1 307 ASP 307 307 307 ASP ASP D . n 
D 1 308 PHE 308 308 308 PHE PHE D . n 
D 1 309 LEU 309 309 309 LEU LEU D . n 
D 1 310 GLU 310 310 310 GLU GLU D . n 
D 1 311 ASP 311 311 311 ASP ASP D . n 
D 1 312 LEU 312 312 312 LEU LEU D . n 
D 1 313 SER 313 313 ?   ?   ?   D . n 
E 1 1   MET 1   1   ?   ?   ?   E . n 
E 1 2   GLY 2   2   ?   ?   ?   E . n 
E 1 3   GLY 3   3   ?   ?   ?   E . n 
E 1 4   GLU 4   4   ?   ?   ?   E . n 
E 1 5   VAL 5   5   ?   ?   ?   E . n 
E 1 6   GLU 6   6   ?   ?   ?   E . n 
E 1 7   GLU 7   7   7   GLU GLU E . n 
E 1 8   PRO 8   8   8   PRO PRO E . n 
E 1 9   GLU 9   9   9   GLU GLU E . n 
E 1 10  PRO 10  10  10  PRO PRO E . n 
E 1 11  GLN 11  11  11  GLN GLN E . n 
E 1 12  MET 12  12  12  MET MET E . n 
E 1 13  VAL 13  13  13  VAL VAL E . n 
E 1 14  LEU 14  14  14  LEU LEU E . n 
E 1 15  SER 15  15  15  SER SER E . n 
E 1 16  PRO 16  16  16  PRO PRO E . n 
E 1 17  LEU 17  17  17  LEU LEU E . n 
E 1 18  THR 18  18  18  THR THR E . n 
E 1 19  SER 19  19  19  SER SER E . n 
E 1 20  ALA 20  20  20  ALA ALA E . n 
E 1 21  ALA 21  21  21  ALA ALA E . n 
E 1 22  ILE 22  22  22  ILE ILE E . n 
E 1 23  PHE 23  23  23  PHE PHE E . n 
E 1 24  LEU 24  24  24  LEU LEU E . n 
E 1 25  VAL 25  25  25  VAL VAL E . n 
E 1 26  VAL 26  26  26  VAL VAL E . n 
E 1 27  THR 27  27  27  THR THR E . n 
E 1 28  ILE 28  28  28  ILE ILE E . n 
E 1 29  ASP 29  29  29  ASP ASP E . n 
E 1 30  SER 30  30  30  SER SER E . n 
E 1 31  GLY 31  31  31  GLY GLY E . n 
E 1 32  GLY 32  32  32  GLY GLY E . n 
E 1 33  GLU 33  33  33  GLU GLU E . n 
E 1 34  ASP 34  34  34  ASP ASP E . n 
E 1 35  THR 35  35  35  THR THR E . n 
E 1 36  VAL 36  36  36  VAL VAL E . n 
E 1 37  ARG 37  37  37  ARG ARG E . n 
E 1 38  ASP 38  38  38  ASP ASP E . n 
E 1 39  LEU 39  39  39  LEU LEU E . n 
E 1 40  LEU 40  40  40  LEU LEU E . n 
E 1 41  SER 41  41  41  SER SER E . n 
E 1 42  ASP 42  42  42  ASP ASP E . n 
E 1 43  VAL 43  43  43  VAL VAL E . n 
E 1 44  ALA 44  44  44  ALA ALA E . n 
E 1 45  SER 45  45  45  SER SER E . n 
E 1 46  LEU 46  46  46  LEU LEU E . n 
E 1 47  GLU 47  47  47  GLU GLU E . n 
E 1 48  ARG 48  48  48  ARG ARG E . n 
E 1 49  ALA 49  49  49  ALA ALA E . n 
E 1 50  VAL 50  50  50  VAL VAL E . n 
E 1 51  GLY 51  51  51  GLY GLY E . n 
E 1 52  PHE 52  52  52  PHE PHE E . n 
E 1 53  ARG 53  53  53  ARG ARG E . n 
E 1 54  ALA 54  54  54  ALA ALA E . n 
E 1 55  GLN 55  55  55  GLN GLN E . n 
E 1 56  PRO 56  56  56  PRO PRO E . n 
E 1 57  ASP 57  57  57  ASP ASP E . n 
E 1 58  GLY 58  58  58  GLY GLY E . n 
E 1 59  ARG 59  59  59  ARG ARG E . n 
E 1 60  LEU 60  60  60  LEU LEU E . n 
E 1 61  SER 61  61  61  SER SER E . n 
E 1 62  CYS 62  62  62  CYS CYS E . n 
E 1 63  VAL 63  63  63  VAL VAL E . n 
E 1 64  THR 64  64  64  THR THR E . n 
E 1 65  GLY 65  65  65  GLY GLY E . n 
E 1 66  ILE 66  66  66  ILE ILE E . n 
E 1 67  GLY 67  67  67  GLY GLY E . n 
E 1 68  SER 68  68  68  SER SER E . n 
E 1 69  GLU 69  69  69  GLU GLU E . n 
E 1 70  ALA 70  70  70  ALA ALA E . n 
E 1 71  TRP 71  71  71  TRP TRP E . n 
E 1 72  ASP 72  72  72  ASP ASP E . n 
E 1 73  ARG 73  73  73  ARG ARG E . n 
E 1 74  LEU 74  74  74  LEU LEU E . n 
E 1 75  PHE 75  75  75  PHE PHE E . n 
E 1 76  SER 76  76  76  SER SER E . n 
E 1 77  GLY 77  77  77  GLY GLY E . n 
E 1 78  ALA 78  78  78  ALA ALA E . n 
E 1 79  ARG 79  79  79  ARG ARG E . n 
E 1 80  PRO 80  80  80  PRO PRO E . n 
E 1 81  ALA 81  81  81  ALA ALA E . n 
E 1 82  GLY 82  82  82  GLY GLY E . n 
E 1 83  LEU 83  83  83  LEU LEU E . n 
E 1 84  HIS 84  84  84  HIS HIS E . n 
E 1 85  PRO 85  85  85  PRO PRO E . n 
E 1 86  PHE 86  86  86  PHE PHE E . n 
E 1 87  ARG 87  87  87  ARG ARG E . n 
E 1 88  GLU 88  88  88  GLU GLU E . n 
E 1 89  LEU 89  89  89  LEU LEU E . n 
E 1 90  ASP 90  90  90  ASP ASP E . n 
E 1 91  GLY 91  91  91  GLY GLY E . n 
E 1 92  PRO 92  92  92  PRO PRO E . n 
E 1 93  VAL 93  93  93  VAL VAL E . n 
E 1 94  HIS 94  94  94  HIS HIS E . n 
E 1 95  ARG 95  95  95  ARG ARG E . n 
E 1 96  ALA 96  96  96  ALA ALA E . n 
E 1 97  VAL 97  97  97  VAL VAL E . n 
E 1 98  ALA 98  98  98  ALA ALA E . n 
E 1 99  THR 99  99  99  THR THR E . n 
E 1 100 PRO 100 100 100 PRO PRO E . n 
E 1 101 GLY 101 101 101 GLY GLY E . n 
E 1 102 ASP 102 102 102 ASP ASP E . n 
E 1 103 LEU 103 103 103 LEU LEU E . n 
E 1 104 LEU 104 104 104 LEU LEU E . n 
E 1 105 PHE 105 105 105 PHE PHE E . n 
E 1 106 HIS 106 106 106 HIS HIS E . n 
E 1 107 ILE 107 107 107 ILE ILE E . n 
E 1 108 ARG 108 108 108 ARG ARG E . n 
E 1 109 ALA 109 109 109 ALA ALA E . n 
E 1 110 SER 110 110 110 SER SER E . n 
E 1 111 ARG 111 111 111 ARG ARG E . n 
E 1 112 LEU 112 112 112 LEU LEU E . n 
E 1 113 ASP 113 113 113 ASP ASP E . n 
E 1 114 LEU 114 114 114 LEU LEU E . n 
E 1 115 CYS 115 115 115 CYS CYS E . n 
E 1 116 PHE 116 116 116 PHE PHE E . n 
E 1 117 ALA 117 117 117 ALA ALA E . n 
E 1 118 LEU 118 118 118 LEU LEU E . n 
E 1 119 ALA 119 119 119 ALA ALA E . n 
E 1 120 THR 120 120 120 THR THR E . n 
E 1 121 GLU 121 121 121 GLU GLU E . n 
E 1 122 ILE 122 122 122 ILE ILE E . n 
E 1 123 MET 123 123 123 MET MET E . n 
E 1 124 GLY 124 124 124 GLY GLY E . n 
E 1 125 ARG 125 125 125 ARG ARG E . n 
E 1 126 LEU 126 126 126 LEU LEU E . n 
E 1 127 ARG 127 127 127 ARG ARG E . n 
E 1 128 GLY 128 128 128 GLY GLY E . n 
E 1 129 ALA 129 129 129 ALA ALA E . n 
E 1 130 VAL 130 130 130 VAL VAL E . n 
E 1 131 THR 131 131 131 THR THR E . n 
E 1 132 PRO 132 132 132 PRO PRO E . n 
E 1 133 GLN 133 133 133 GLN GLN E . n 
E 1 134 ASP 134 134 134 ASP ASP E . n 
E 1 135 GLU 135 135 135 GLU GLU E . n 
E 1 136 VAL 136 136 136 VAL VAL E . n 
E 1 137 HIS 137 137 137 HIS HIS E . n 
E 1 138 GLY 138 138 138 GLY GLY E . n 
E 1 139 PHE 139 139 139 PHE PHE E . n 
E 1 140 LYS 140 140 140 LYS LYS E . n 
E 1 141 TYR 141 141 141 TYR TYR E . n 
E 1 142 PHE 142 142 142 PHE PHE E . n 
E 1 143 ASP 143 143 143 ASP ASP E . n 
E 1 144 GLU 144 144 144 GLU GLU E . n 
E 1 145 ARG 145 145 145 ARG ARG E . n 
E 1 146 ASP 146 146 146 ASP ASP E . n 
E 1 147 MET 147 147 147 MET MET E . n 
E 1 148 LEU 148 148 148 LEU LEU E . n 
E 1 149 GLY 149 149 149 GLY GLY E . n 
E 1 150 PHE 150 150 150 PHE PHE E . n 
E 1 151 VAL 151 151 151 VAL VAL E . n 
E 1 152 ASP 152 152 152 ASP ASP E . n 
E 1 153 GLY 153 153 153 GLY GLY E . n 
E 1 154 THR 154 154 154 THR THR E . n 
E 1 155 GLU 155 155 155 GLU GLU E . n 
E 1 156 ASN 156 156 156 ASN ASN E . n 
E 1 157 PRO 157 157 157 PRO PRO E . n 
E 1 158 THR 158 158 158 THR THR E . n 
E 1 159 GLY 159 159 159 GLY GLY E . n 
E 1 160 ALA 160 160 160 ALA ALA E . n 
E 1 161 ALA 161 161 161 ALA ALA E . n 
E 1 162 ALA 162 162 162 ALA ALA E . n 
E 1 163 ARG 163 163 163 ARG ARG E . n 
E 1 164 ARG 164 164 164 ARG ARG E . n 
E 1 165 ALA 165 165 165 ALA ALA E . n 
E 1 166 VAL 166 166 166 VAL VAL E . n 
E 1 167 LEU 167 167 167 LEU LEU E . n 
E 1 168 VAL 168 168 168 VAL VAL E . n 
E 1 169 GLY 169 169 169 GLY GLY E . n 
E 1 170 ALA 170 170 170 ALA ALA E . n 
E 1 171 GLU 171 171 171 GLU GLU E . n 
E 1 172 ASP 172 172 172 ASP ASP E . n 
E 1 173 PRO 173 173 173 PRO PRO E . n 
E 1 174 ALA 174 174 174 ALA ALA E . n 
E 1 175 PHE 175 175 175 PHE PHE E . n 
E 1 176 ALA 176 176 176 ALA ALA E . n 
E 1 177 GLY 177 177 177 GLY GLY E . n 
E 1 178 GLY 178 178 178 GLY GLY E . n 
E 1 179 SER 179 179 179 SER SER E . n 
E 1 180 TYR 180 180 180 TYR TYR E . n 
E 1 181 ALA 181 181 181 ALA ALA E . n 
E 1 182 VAL 182 182 182 VAL VAL E . n 
E 1 183 VAL 183 183 183 VAL VAL E . n 
E 1 184 GLN 184 184 184 GLN GLN E . n 
E 1 185 LYS 185 185 185 LYS LYS E . n 
E 1 186 TYR 186 186 186 TYR TYR E . n 
E 1 187 LEU 187 187 187 LEU LEU E . n 
E 1 188 HIS 188 188 188 HIS HIS E . n 
E 1 189 ASP 189 189 189 ASP ASP E . n 
E 1 190 ILE 190 190 190 ILE ILE E . n 
E 1 191 ASP 191 191 191 ASP ASP E . n 
E 1 192 ALA 192 192 192 ALA ALA E . n 
E 1 193 TRP 193 193 193 TRP TRP E . n 
E 1 194 GLU 194 194 194 GLU GLU E . n 
E 1 195 GLY 195 195 195 GLY GLY E . n 
E 1 196 LEU 196 196 196 LEU LEU E . n 
E 1 197 SER 197 197 197 SER SER E . n 
E 1 198 VAL 198 198 198 VAL VAL E . n 
E 1 199 GLU 199 199 199 GLU GLU E . n 
E 1 200 ALA 200 200 200 ALA ALA E . n 
E 1 201 GLN 201 201 201 GLN GLN E . n 
E 1 202 GLU 202 202 202 GLU GLU E . n 
E 1 203 ARG 203 203 203 ARG ARG E . n 
E 1 204 VAL 204 204 204 VAL VAL E . n 
E 1 205 ILE 205 205 205 ILE ILE E . n 
E 1 206 GLY 206 206 206 GLY GLY E . n 
E 1 207 ARG 207 207 207 ARG ARG E . n 
E 1 208 ARG 208 208 208 ARG ARG E . n 
E 1 209 LYS 209 209 209 LYS LYS E . n 
E 1 210 MET 210 210 210 MET MET E . n 
E 1 211 THR 211 211 211 THR THR E . n 
E 1 212 ASP 212 212 212 ASP ASP E . n 
E 1 213 VAL 213 213 213 VAL VAL E . n 
E 1 214 GLU 214 214 214 GLU GLU E . n 
E 1 215 LEU 215 215 215 LEU LEU E . n 
E 1 216 SER 216 216 216 SER SER E . n 
E 1 217 ASP 217 217 217 ASP ASP E . n 
E 1 218 ASP 218 218 218 ASP ASP E . n 
E 1 219 VAL 219 219 219 VAL VAL E . n 
E 1 220 LYS 220 220 220 LYS LYS E . n 
E 1 221 PRO 221 221 221 PRO PRO E . n 
E 1 222 ALA 222 222 222 ALA ALA E . n 
E 1 223 ASP 223 223 223 ASP ASP E . n 
E 1 224 SER 224 224 224 SER SER E . n 
E 1 225 HIS 225 225 225 HIS HIS E . n 
E 1 226 VAL 226 226 226 VAL VAL E . n 
E 1 227 ALA 227 227 227 ALA ALA E . n 
E 1 228 LEU 228 228 228 LEU LEU E . n 
E 1 229 THR 229 229 229 THR THR E . n 
E 1 230 SER 230 230 230 SER SER E . n 
E 1 231 VAL 231 231 231 VAL VAL E . n 
E 1 232 THR 232 232 232 THR THR E . n 
E 1 233 GLY 233 233 233 GLY GLY E . n 
E 1 234 PRO 234 234 234 PRO PRO E . n 
E 1 235 ASP 235 235 235 ASP ASP E . n 
E 1 236 GLY 236 236 236 GLY GLY E . n 
E 1 237 SER 237 237 237 SER SER E . n 
E 1 238 ASP 238 238 238 ASP ASP E . n 
E 1 239 LEU 239 239 239 LEU LEU E . n 
E 1 240 GLU 240 240 240 GLU GLU E . n 
E 1 241 ILE 241 241 241 ILE ILE E . n 
E 1 242 LEU 242 242 242 LEU LEU E . n 
E 1 243 ARG 243 243 243 ARG ARG E . n 
E 1 244 ASP 244 244 244 ASP ASP E . n 
E 1 245 ASN 245 245 245 ASN ASN E . n 
E 1 246 MET 246 246 246 MET MET E . n 
E 1 247 PRO 247 247 247 PRO PRO E . n 
E 1 248 PHE 248 248 248 PHE PHE E . n 
E 1 249 GLY 249 249 249 GLY GLY E . n 
E 1 250 SER 250 250 250 SER SER E . n 
E 1 251 VAL 251 251 251 VAL VAL E . n 
E 1 252 GLY 252 252 252 GLY GLY E . n 
E 1 253 ARG 253 253 253 ARG ARG E . n 
E 1 254 GLU 254 254 254 GLU GLU E . n 
E 1 255 GLU 255 255 255 GLU GLU E . n 
E 1 256 PHE 256 256 256 PHE PHE E . n 
E 1 257 GLY 257 257 257 GLY GLY E . n 
E 1 258 THR 258 258 258 THR THR E . n 
E 1 259 TYR 259 259 259 TYR TYR E . n 
E 1 260 PHE 260 260 260 PHE PHE E . n 
E 1 261 ILE 261 261 261 ILE ILE E . n 
E 1 262 GLY 262 262 262 GLY GLY E . n 
E 1 263 TYR 263 263 263 TYR TYR E . n 
E 1 264 ALA 264 264 264 ALA ALA E . n 
E 1 265 ARG 265 265 265 ARG ARG E . n 
E 1 266 THR 266 266 266 THR THR E . n 
E 1 267 PRO 267 267 267 PRO PRO E . n 
E 1 268 GLU 268 268 268 GLU GLU E . n 
E 1 269 VAL 269 269 269 VAL VAL E . n 
E 1 270 THR 270 270 270 THR THR E . n 
E 1 271 GLU 271 271 271 GLU GLU E . n 
E 1 272 THR 272 272 272 THR THR E . n 
E 1 273 MET 273 273 273 MET MET E . n 
E 1 274 LEU 274 274 274 LEU LEU E . n 
E 1 275 GLU 275 275 275 GLU GLU E . n 
E 1 276 ARG 276 276 276 ARG ARG E . n 
E 1 277 MET 277 277 277 MET MET E . n 
E 1 278 PHE 278 278 278 PHE PHE E . n 
E 1 279 LEU 279 279 279 LEU LEU E . n 
E 1 280 GLY 280 280 280 GLY GLY E . n 
E 1 281 THR 281 281 281 THR THR E . n 
E 1 282 ALA 282 282 282 ALA ALA E . n 
E 1 283 SER 283 283 283 SER SER E . n 
E 1 284 ALA 284 284 284 ALA ALA E . n 
E 1 285 PRO 285 285 285 PRO PRO E . n 
E 1 286 HIS 286 286 286 HIS HIS E . n 
E 1 287 ASP 287 287 287 ASP ASP E . n 
E 1 288 ARG 288 288 288 ARG ARG E . n 
E 1 289 ILE 289 289 289 ILE ILE E . n 
E 1 290 LEU 290 290 290 LEU LEU E . n 
E 1 291 ASP 291 291 291 ASP ASP E . n 
E 1 292 PHE 292 292 292 PHE PHE E . n 
E 1 293 SER 293 293 293 SER SER E . n 
E 1 294 THR 294 294 294 THR THR E . n 
E 1 295 ALA 295 295 295 ALA ALA E . n 
E 1 296 VAL 296 296 296 VAL VAL E . n 
E 1 297 THR 297 297 297 THR THR E . n 
E 1 298 GLY 298 298 298 GLY GLY E . n 
E 1 299 SER 299 299 299 SER SER E . n 
E 1 300 LEU 300 300 300 LEU LEU E . n 
E 1 301 PHE 301 301 301 PHE PHE E . n 
E 1 302 PHE 302 302 302 PHE PHE E . n 
E 1 303 THR 303 303 303 THR THR E . n 
E 1 304 PRO 304 304 304 PRO PRO E . n 
E 1 305 ALA 305 305 305 ALA ALA E . n 
E 1 306 ALA 306 306 306 ALA ALA E . n 
E 1 307 ASP 307 307 307 ASP ASP E . n 
E 1 308 PHE 308 308 308 PHE PHE E . n 
E 1 309 LEU 309 309 309 LEU LEU E . n 
E 1 310 GLU 310 310 310 GLU GLU E . n 
E 1 311 ASP 311 311 311 ASP ASP E . n 
E 1 312 LEU 312 312 312 LEU LEU E . n 
E 1 313 SER 313 313 ?   ?   ?   E . n 
F 1 1   MET 1   1   ?   ?   ?   F . n 
F 1 2   GLY 2   2   ?   ?   ?   F . n 
F 1 3   GLY 3   3   ?   ?   ?   F . n 
F 1 4   GLU 4   4   ?   ?   ?   F . n 
F 1 5   VAL 5   5   ?   ?   ?   F . n 
F 1 6   GLU 6   6   ?   ?   ?   F . n 
F 1 7   GLU 7   7   ?   ?   ?   F . n 
F 1 8   PRO 8   8   8   PRO PRO F . n 
F 1 9   GLU 9   9   9   GLU GLU F . n 
F 1 10  PRO 10  10  10  PRO PRO F . n 
F 1 11  GLN 11  11  11  GLN GLN F . n 
F 1 12  MET 12  12  12  MET MET F . n 
F 1 13  VAL 13  13  13  VAL VAL F . n 
F 1 14  LEU 14  14  14  LEU LEU F . n 
F 1 15  SER 15  15  15  SER SER F . n 
F 1 16  PRO 16  16  16  PRO PRO F . n 
F 1 17  LEU 17  17  17  LEU LEU F . n 
F 1 18  THR 18  18  18  THR THR F . n 
F 1 19  SER 19  19  19  SER SER F . n 
F 1 20  ALA 20  20  20  ALA ALA F . n 
F 1 21  ALA 21  21  21  ALA ALA F . n 
F 1 22  ILE 22  22  22  ILE ILE F . n 
F 1 23  PHE 23  23  23  PHE PHE F . n 
F 1 24  LEU 24  24  24  LEU LEU F . n 
F 1 25  VAL 25  25  25  VAL VAL F . n 
F 1 26  VAL 26  26  26  VAL VAL F . n 
F 1 27  THR 27  27  27  THR THR F . n 
F 1 28  ILE 28  28  28  ILE ILE F . n 
F 1 29  ASP 29  29  29  ASP ASP F . n 
F 1 30  SER 30  30  30  SER SER F . n 
F 1 31  GLY 31  31  31  GLY GLY F . n 
F 1 32  GLY 32  32  32  GLY GLY F . n 
F 1 33  GLU 33  33  33  GLU GLU F . n 
F 1 34  ASP 34  34  34  ASP ASP F . n 
F 1 35  THR 35  35  35  THR THR F . n 
F 1 36  VAL 36  36  36  VAL VAL F . n 
F 1 37  ARG 37  37  37  ARG ARG F . n 
F 1 38  ASP 38  38  38  ASP ASP F . n 
F 1 39  LEU 39  39  39  LEU LEU F . n 
F 1 40  LEU 40  40  40  LEU LEU F . n 
F 1 41  SER 41  41  41  SER SER F . n 
F 1 42  ASP 42  42  42  ASP ASP F . n 
F 1 43  VAL 43  43  43  VAL VAL F . n 
F 1 44  ALA 44  44  44  ALA ALA F . n 
F 1 45  SER 45  45  45  SER SER F . n 
F 1 46  LEU 46  46  46  LEU LEU F . n 
F 1 47  GLU 47  47  47  GLU GLU F . n 
F 1 48  ARG 48  48  48  ARG ARG F . n 
F 1 49  ALA 49  49  49  ALA ALA F . n 
F 1 50  VAL 50  50  50  VAL VAL F . n 
F 1 51  GLY 51  51  51  GLY GLY F . n 
F 1 52  PHE 52  52  52  PHE PHE F . n 
F 1 53  ARG 53  53  53  ARG ARG F . n 
F 1 54  ALA 54  54  54  ALA ALA F . n 
F 1 55  GLN 55  55  55  GLN GLN F . n 
F 1 56  PRO 56  56  56  PRO PRO F . n 
F 1 57  ASP 57  57  57  ASP ASP F . n 
F 1 58  GLY 58  58  58  GLY GLY F . n 
F 1 59  ARG 59  59  59  ARG ARG F . n 
F 1 60  LEU 60  60  60  LEU LEU F . n 
F 1 61  SER 61  61  61  SER SER F . n 
F 1 62  CYS 62  62  62  CYS CYS F . n 
F 1 63  VAL 63  63  63  VAL VAL F . n 
F 1 64  THR 64  64  64  THR THR F . n 
F 1 65  GLY 65  65  65  GLY GLY F . n 
F 1 66  ILE 66  66  66  ILE ILE F . n 
F 1 67  GLY 67  67  67  GLY GLY F . n 
F 1 68  SER 68  68  68  SER SER F . n 
F 1 69  GLU 69  69  69  GLU GLU F . n 
F 1 70  ALA 70  70  70  ALA ALA F . n 
F 1 71  TRP 71  71  71  TRP TRP F . n 
F 1 72  ASP 72  72  72  ASP ASP F . n 
F 1 73  ARG 73  73  73  ARG ARG F . n 
F 1 74  LEU 74  74  74  LEU LEU F . n 
F 1 75  PHE 75  75  75  PHE PHE F . n 
F 1 76  SER 76  76  76  SER SER F . n 
F 1 77  GLY 77  77  77  GLY GLY F . n 
F 1 78  ALA 78  78  78  ALA ALA F . n 
F 1 79  ARG 79  79  79  ARG ARG F . n 
F 1 80  PRO 80  80  80  PRO PRO F . n 
F 1 81  ALA 81  81  81  ALA ALA F . n 
F 1 82  GLY 82  82  82  GLY GLY F . n 
F 1 83  LEU 83  83  83  LEU LEU F . n 
F 1 84  HIS 84  84  84  HIS HIS F . n 
F 1 85  PRO 85  85  85  PRO PRO F . n 
F 1 86  PHE 86  86  86  PHE PHE F . n 
F 1 87  ARG 87  87  87  ARG ARG F . n 
F 1 88  GLU 88  88  88  GLU GLU F . n 
F 1 89  LEU 89  89  89  LEU LEU F . n 
F 1 90  ASP 90  90  90  ASP ASP F . n 
F 1 91  GLY 91  91  91  GLY GLY F . n 
F 1 92  PRO 92  92  92  PRO PRO F . n 
F 1 93  VAL 93  93  93  VAL VAL F . n 
F 1 94  HIS 94  94  94  HIS HIS F . n 
F 1 95  ARG 95  95  95  ARG ARG F . n 
F 1 96  ALA 96  96  96  ALA ALA F . n 
F 1 97  VAL 97  97  97  VAL VAL F . n 
F 1 98  ALA 98  98  98  ALA ALA F . n 
F 1 99  THR 99  99  99  THR THR F . n 
F 1 100 PRO 100 100 100 PRO PRO F . n 
F 1 101 GLY 101 101 101 GLY GLY F . n 
F 1 102 ASP 102 102 102 ASP ASP F . n 
F 1 103 LEU 103 103 103 LEU LEU F . n 
F 1 104 LEU 104 104 104 LEU LEU F . n 
F 1 105 PHE 105 105 105 PHE PHE F . n 
F 1 106 HIS 106 106 106 HIS HIS F . n 
F 1 107 ILE 107 107 107 ILE ILE F . n 
F 1 108 ARG 108 108 108 ARG ARG F . n 
F 1 109 ALA 109 109 109 ALA ALA F . n 
F 1 110 SER 110 110 110 SER SER F . n 
F 1 111 ARG 111 111 111 ARG ARG F . n 
F 1 112 LEU 112 112 112 LEU LEU F . n 
F 1 113 ASP 113 113 113 ASP ASP F . n 
F 1 114 LEU 114 114 114 LEU LEU F . n 
F 1 115 CYS 115 115 115 CYS CYS F . n 
F 1 116 PHE 116 116 116 PHE PHE F . n 
F 1 117 ALA 117 117 117 ALA ALA F . n 
F 1 118 LEU 118 118 118 LEU LEU F . n 
F 1 119 ALA 119 119 119 ALA ALA F . n 
F 1 120 THR 120 120 120 THR THR F . n 
F 1 121 GLU 121 121 121 GLU GLU F . n 
F 1 122 ILE 122 122 122 ILE ILE F . n 
F 1 123 MET 123 123 123 MET MET F . n 
F 1 124 GLY 124 124 124 GLY GLY F . n 
F 1 125 ARG 125 125 125 ARG ARG F . n 
F 1 126 LEU 126 126 126 LEU LEU F . n 
F 1 127 ARG 127 127 127 ARG ARG F . n 
F 1 128 GLY 128 128 128 GLY GLY F . n 
F 1 129 ALA 129 129 129 ALA ALA F . n 
F 1 130 VAL 130 130 130 VAL VAL F . n 
F 1 131 THR 131 131 131 THR THR F . n 
F 1 132 PRO 132 132 132 PRO PRO F . n 
F 1 133 GLN 133 133 133 GLN GLN F . n 
F 1 134 ASP 134 134 134 ASP ASP F . n 
F 1 135 GLU 135 135 135 GLU GLU F . n 
F 1 136 VAL 136 136 136 VAL VAL F . n 
F 1 137 HIS 137 137 137 HIS HIS F . n 
F 1 138 GLY 138 138 138 GLY GLY F . n 
F 1 139 PHE 139 139 139 PHE PHE F . n 
F 1 140 LYS 140 140 140 LYS LYS F . n 
F 1 141 TYR 141 141 141 TYR TYR F . n 
F 1 142 PHE 142 142 142 PHE PHE F . n 
F 1 143 ASP 143 143 143 ASP ASP F . n 
F 1 144 GLU 144 144 144 GLU GLU F . n 
F 1 145 ARG 145 145 145 ARG ARG F . n 
F 1 146 ASP 146 146 146 ASP ASP F . n 
F 1 147 MET 147 147 147 MET MET F . n 
F 1 148 LEU 148 148 148 LEU LEU F . n 
F 1 149 GLY 149 149 149 GLY GLY F . n 
F 1 150 PHE 150 150 150 PHE PHE F . n 
F 1 151 VAL 151 151 151 VAL VAL F . n 
F 1 152 ASP 152 152 152 ASP ASP F . n 
F 1 153 GLY 153 153 153 GLY GLY F . n 
F 1 154 THR 154 154 154 THR THR F . n 
F 1 155 GLU 155 155 155 GLU GLU F . n 
F 1 156 ASN 156 156 156 ASN ASN F . n 
F 1 157 PRO 157 157 157 PRO PRO F . n 
F 1 158 THR 158 158 158 THR THR F . n 
F 1 159 GLY 159 159 159 GLY GLY F . n 
F 1 160 ALA 160 160 160 ALA ALA F . n 
F 1 161 ALA 161 161 161 ALA ALA F . n 
F 1 162 ALA 162 162 162 ALA ALA F . n 
F 1 163 ARG 163 163 163 ARG ARG F . n 
F 1 164 ARG 164 164 164 ARG ARG F . n 
F 1 165 ALA 165 165 165 ALA ALA F . n 
F 1 166 VAL 166 166 166 VAL VAL F . n 
F 1 167 LEU 167 167 167 LEU LEU F . n 
F 1 168 VAL 168 168 168 VAL VAL F . n 
F 1 169 GLY 169 169 169 GLY GLY F . n 
F 1 170 ALA 170 170 170 ALA ALA F . n 
F 1 171 GLU 171 171 171 GLU GLU F . n 
F 1 172 ASP 172 172 172 ASP ASP F . n 
F 1 173 PRO 173 173 173 PRO PRO F . n 
F 1 174 ALA 174 174 174 ALA ALA F . n 
F 1 175 PHE 175 175 175 PHE PHE F . n 
F 1 176 ALA 176 176 176 ALA ALA F . n 
F 1 177 GLY 177 177 177 GLY GLY F . n 
F 1 178 GLY 178 178 178 GLY GLY F . n 
F 1 179 SER 179 179 179 SER SER F . n 
F 1 180 TYR 180 180 180 TYR TYR F . n 
F 1 181 ALA 181 181 181 ALA ALA F . n 
F 1 182 VAL 182 182 182 VAL VAL F . n 
F 1 183 VAL 183 183 183 VAL VAL F . n 
F 1 184 GLN 184 184 184 GLN GLN F . n 
F 1 185 LYS 185 185 185 LYS LYS F . n 
F 1 186 TYR 186 186 186 TYR TYR F . n 
F 1 187 LEU 187 187 187 LEU LEU F . n 
F 1 188 HIS 188 188 188 HIS HIS F . n 
F 1 189 ASP 189 189 189 ASP ASP F . n 
F 1 190 ILE 190 190 190 ILE ILE F . n 
F 1 191 ASP 191 191 191 ASP ASP F . n 
F 1 192 ALA 192 192 192 ALA ALA F . n 
F 1 193 TRP 193 193 193 TRP TRP F . n 
F 1 194 GLU 194 194 194 GLU GLU F . n 
F 1 195 GLY 195 195 195 GLY GLY F . n 
F 1 196 LEU 196 196 196 LEU LEU F . n 
F 1 197 SER 197 197 197 SER SER F . n 
F 1 198 VAL 198 198 198 VAL VAL F . n 
F 1 199 GLU 199 199 199 GLU GLU F . n 
F 1 200 ALA 200 200 200 ALA ALA F . n 
F 1 201 GLN 201 201 201 GLN GLN F . n 
F 1 202 GLU 202 202 202 GLU GLU F . n 
F 1 203 ARG 203 203 203 ARG ARG F . n 
F 1 204 VAL 204 204 204 VAL VAL F . n 
F 1 205 ILE 205 205 205 ILE ILE F . n 
F 1 206 GLY 206 206 206 GLY GLY F . n 
F 1 207 ARG 207 207 207 ARG ARG F . n 
F 1 208 ARG 208 208 208 ARG ARG F . n 
F 1 209 LYS 209 209 209 LYS LYS F . n 
F 1 210 MET 210 210 210 MET MET F . n 
F 1 211 THR 211 211 211 THR THR F . n 
F 1 212 ASP 212 212 212 ASP ASP F . n 
F 1 213 VAL 213 213 213 VAL VAL F . n 
F 1 214 GLU 214 214 214 GLU GLU F . n 
F 1 215 LEU 215 215 215 LEU LEU F . n 
F 1 216 SER 216 216 216 SER SER F . n 
F 1 217 ASP 217 217 217 ASP ASP F . n 
F 1 218 ASP 218 218 218 ASP ASP F . n 
F 1 219 VAL 219 219 219 VAL VAL F . n 
F 1 220 LYS 220 220 220 LYS LYS F . n 
F 1 221 PRO 221 221 221 PRO PRO F . n 
F 1 222 ALA 222 222 222 ALA ALA F . n 
F 1 223 ASP 223 223 223 ASP ASP F . n 
F 1 224 SER 224 224 224 SER SER F . n 
F 1 225 HIS 225 225 225 HIS HIS F . n 
F 1 226 VAL 226 226 226 VAL VAL F . n 
F 1 227 ALA 227 227 227 ALA ALA F . n 
F 1 228 LEU 228 228 228 LEU LEU F . n 
F 1 229 THR 229 229 229 THR THR F . n 
F 1 230 SER 230 230 230 SER SER F . n 
F 1 231 VAL 231 231 231 VAL VAL F . n 
F 1 232 THR 232 232 232 THR THR F . n 
F 1 233 GLY 233 233 233 GLY GLY F . n 
F 1 234 PRO 234 234 234 PRO PRO F . n 
F 1 235 ASP 235 235 235 ASP ASP F . n 
F 1 236 GLY 236 236 236 GLY GLY F . n 
F 1 237 SER 237 237 237 SER SER F . n 
F 1 238 ASP 238 238 238 ASP ASP F . n 
F 1 239 LEU 239 239 239 LEU LEU F . n 
F 1 240 GLU 240 240 240 GLU GLU F . n 
F 1 241 ILE 241 241 241 ILE ILE F . n 
F 1 242 LEU 242 242 242 LEU LEU F . n 
F 1 243 ARG 243 243 243 ARG ARG F . n 
F 1 244 ASP 244 244 244 ASP ASP F . n 
F 1 245 ASN 245 245 245 ASN ASN F . n 
F 1 246 MET 246 246 246 MET MET F . n 
F 1 247 PRO 247 247 247 PRO PRO F . n 
F 1 248 PHE 248 248 248 PHE PHE F . n 
F 1 249 GLY 249 249 249 GLY GLY F . n 
F 1 250 SER 250 250 250 SER SER F . n 
F 1 251 VAL 251 251 251 VAL VAL F . n 
F 1 252 GLY 252 252 252 GLY GLY F . n 
F 1 253 ARG 253 253 253 ARG ARG F . n 
F 1 254 GLU 254 254 254 GLU GLU F . n 
F 1 255 GLU 255 255 255 GLU GLU F . n 
F 1 256 PHE 256 256 256 PHE PHE F . n 
F 1 257 GLY 257 257 257 GLY GLY F . n 
F 1 258 THR 258 258 258 THR THR F . n 
F 1 259 TYR 259 259 259 TYR TYR F . n 
F 1 260 PHE 260 260 260 PHE PHE F . n 
F 1 261 ILE 261 261 261 ILE ILE F . n 
F 1 262 GLY 262 262 262 GLY GLY F . n 
F 1 263 TYR 263 263 263 TYR TYR F . n 
F 1 264 ALA 264 264 264 ALA ALA F . n 
F 1 265 ARG 265 265 265 ARG ARG F . n 
F 1 266 THR 266 266 266 THR THR F . n 
F 1 267 PRO 267 267 267 PRO PRO F . n 
F 1 268 GLU 268 268 268 GLU GLU F . n 
F 1 269 VAL 269 269 269 VAL VAL F . n 
F 1 270 THR 270 270 270 THR THR F . n 
F 1 271 GLU 271 271 271 GLU GLU F . n 
F 1 272 THR 272 272 272 THR THR F . n 
F 1 273 MET 273 273 273 MET MET F . n 
F 1 274 LEU 274 274 274 LEU LEU F . n 
F 1 275 GLU 275 275 275 GLU GLU F . n 
F 1 276 ARG 276 276 276 ARG ARG F . n 
F 1 277 MET 277 277 277 MET MET F . n 
F 1 278 PHE 278 278 278 PHE PHE F . n 
F 1 279 LEU 279 279 279 LEU LEU F . n 
F 1 280 GLY 280 280 280 GLY GLY F . n 
F 1 281 THR 281 281 281 THR THR F . n 
F 1 282 ALA 282 282 282 ALA ALA F . n 
F 1 283 SER 283 283 283 SER SER F . n 
F 1 284 ALA 284 284 284 ALA ALA F . n 
F 1 285 PRO 285 285 285 PRO PRO F . n 
F 1 286 HIS 286 286 286 HIS HIS F . n 
F 1 287 ASP 287 287 287 ASP ASP F . n 
F 1 288 ARG 288 288 288 ARG ARG F . n 
F 1 289 ILE 289 289 289 ILE ILE F . n 
F 1 290 LEU 290 290 290 LEU LEU F . n 
F 1 291 ASP 291 291 291 ASP ASP F . n 
F 1 292 PHE 292 292 292 PHE PHE F . n 
F 1 293 SER 293 293 293 SER SER F . n 
F 1 294 THR 294 294 294 THR THR F . n 
F 1 295 ALA 295 295 295 ALA ALA F . n 
F 1 296 VAL 296 296 296 VAL VAL F . n 
F 1 297 THR 297 297 297 THR THR F . n 
F 1 298 GLY 298 298 298 GLY GLY F . n 
F 1 299 SER 299 299 299 SER SER F . n 
F 1 300 LEU 300 300 300 LEU LEU F . n 
F 1 301 PHE 301 301 301 PHE PHE F . n 
F 1 302 PHE 302 302 302 PHE PHE F . n 
F 1 303 THR 303 303 303 THR THR F . n 
F 1 304 PRO 304 304 304 PRO PRO F . n 
F 1 305 ALA 305 305 305 ALA ALA F . n 
F 1 306 ALA 306 306 306 ALA ALA F . n 
F 1 307 ASP 307 307 307 ASP ASP F . n 
F 1 308 PHE 308 308 308 PHE PHE F . n 
F 1 309 LEU 309 309 309 LEU LEU F . n 
F 1 310 GLU 310 310 310 GLU GLU F . n 
F 1 311 ASP 311 311 311 ASP ASP F . n 
F 1 312 LEU 312 312 312 LEU LEU F . n 
F 1 313 SER 313 313 ?   ?   ?   F . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        HEM 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   HEM 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 2 HEM 1  401 401 HEM HEM A . 
H 3 MG  1  402 1   MG  MG  A . 
I 2 HEM 1  401 401 HEM HEM B . 
J 2 HEM 1  401 401 HEM HEM C . 
K 2 HEM 1  401 401 HEM HEM D . 
L 4 PG4 1  402 402 PG4 PG4 D . 
M 2 HEM 1  401 401 HEM HEM E . 
N 2 HEM 1  401 401 HEM HEM F . 
O 5 HOH 1  501 50  HOH HOH A . 
O 5 HOH 2  502 67  HOH HOH A . 
O 5 HOH 3  503 69  HOH HOH A . 
O 5 HOH 4  504 403 HOH HOH A . 
O 5 HOH 5  505 45  HOH HOH A . 
O 5 HOH 6  506 22  HOH HOH A . 
O 5 HOH 7  507 71  HOH HOH A . 
O 5 HOH 8  508 14  HOH HOH A . 
O 5 HOH 9  509 37  HOH HOH A . 
O 5 HOH 10 510 25  HOH HOH A . 
O 5 HOH 11 511 16  HOH HOH A . 
O 5 HOH 12 512 44  HOH HOH A . 
O 5 HOH 13 513 24  HOH HOH A . 
O 5 HOH 14 514 40  HOH HOH A . 
O 5 HOH 15 515 30  HOH HOH A . 
O 5 HOH 16 516 3   HOH HOH A . 
O 5 HOH 17 517 49  HOH HOH A . 
O 5 HOH 18 518 41  HOH HOH A . 
O 5 HOH 19 519 51  HOH HOH A . 
O 5 HOH 20 520 48  HOH HOH A . 
O 5 HOH 21 521 63  HOH HOH A . 
O 5 HOH 22 522 18  HOH HOH A . 
O 5 HOH 23 523 17  HOH HOH A . 
O 5 HOH 24 524 32  HOH HOH A . 
O 5 HOH 25 525 21  HOH HOH A . 
O 5 HOH 26 526 56  HOH HOH A . 
O 5 HOH 27 527 35  HOH HOH A . 
P 5 HOH 1  501 52  HOH HOH B . 
P 5 HOH 2  502 11  HOH HOH B . 
P 5 HOH 3  503 62  HOH HOH B . 
P 5 HOH 4  504 68  HOH HOH B . 
P 5 HOH 5  505 31  HOH HOH B . 
P 5 HOH 6  506 34  HOH HOH B . 
Q 5 HOH 1  501 74  HOH HOH C . 
Q 5 HOH 2  502 59  HOH HOH C . 
Q 5 HOH 3  503 5   HOH HOH C . 
Q 5 HOH 4  504 6   HOH HOH C . 
Q 5 HOH 5  505 23  HOH HOH C . 
Q 5 HOH 6  506 73  HOH HOH C . 
Q 5 HOH 7  507 55  HOH HOH C . 
Q 5 HOH 8  508 19  HOH HOH C . 
Q 5 HOH 9  509 70  HOH HOH C . 
Q 5 HOH 10 510 27  HOH HOH C . 
R 5 HOH 1  501 404 HOH HOH D . 
R 5 HOH 2  502 72  HOH HOH D . 
R 5 HOH 3  503 46  HOH HOH D . 
R 5 HOH 4  504 9   HOH HOH D . 
R 5 HOH 5  505 13  HOH HOH D . 
R 5 HOH 6  506 66  HOH HOH D . 
R 5 HOH 7  507 28  HOH HOH D . 
R 5 HOH 8  508 29  HOH HOH D . 
R 5 HOH 9  509 8   HOH HOH D . 
R 5 HOH 10 510 43  HOH HOH D . 
R 5 HOH 11 511 15  HOH HOH D . 
R 5 HOH 12 512 26  HOH HOH D . 
R 5 HOH 13 513 20  HOH HOH D . 
R 5 HOH 14 514 38  HOH HOH D . 
R 5 HOH 15 515 39  HOH HOH D . 
R 5 HOH 16 516 36  HOH HOH D . 
S 5 HOH 1  501 60  HOH HOH E . 
S 5 HOH 2  502 12  HOH HOH E . 
S 5 HOH 3  503 33  HOH HOH E . 
S 5 HOH 4  504 53  HOH HOH E . 
S 5 HOH 5  505 47  HOH HOH E . 
S 5 HOH 6  506 42  HOH HOH E . 
S 5 HOH 7  507 64  HOH HOH E . 
T 5 HOH 1  501 54  HOH HOH F . 
T 5 HOH 2  502 57  HOH HOH F . 
T 5 HOH 3  503 75  HOH HOH F . 
T 5 HOH 4  504 65  HOH HOH F . 
T 5 HOH 5  505 58  HOH HOH F . 
T 5 HOH 6  506 4   HOH HOH F . 
T 5 HOH 7  507 61  HOH HOH F . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A GLU 9   ? CD  ? A GLU 9   CD  
2   1 Y 1 A GLU 9   ? OE1 ? A GLU 9   OE1 
3   1 Y 1 A GLU 9   ? OE2 ? A GLU 9   OE2 
4   1 Y 1 A ARG 59  ? CZ  ? A ARG 59  CZ  
5   1 Y 1 A ARG 59  ? NH1 ? A ARG 59  NH1 
6   1 Y 1 A ARG 59  ? NH2 ? A ARG 59  NH2 
7   1 Y 1 A LYS 140 ? NZ  ? A LYS 140 NZ  
8   1 Y 1 A ARG 203 ? CZ  ? A ARG 203 CZ  
9   1 Y 1 A ARG 203 ? NH1 ? A ARG 203 NH1 
10  1 Y 1 A ARG 203 ? NH2 ? A ARG 203 NH2 
11  1 Y 1 B GLU 7   ? CG  ? B GLU 7   CG  
12  1 Y 1 B GLU 7   ? CD  ? B GLU 7   CD  
13  1 Y 1 B GLU 7   ? OE1 ? B GLU 7   OE1 
14  1 Y 1 B GLU 7   ? OE2 ? B GLU 7   OE2 
15  1 Y 1 B GLU 9   ? CG  ? B GLU 9   CG  
16  1 Y 1 B GLU 9   ? CD  ? B GLU 9   CD  
17  1 Y 1 B GLU 9   ? OE1 ? B GLU 9   OE1 
18  1 Y 1 B GLU 9   ? OE2 ? B GLU 9   OE2 
19  1 Y 1 B LEU 17  ? CD1 ? B LEU 17  CD1 
20  1 Y 1 B LEU 17  ? CD2 ? B LEU 17  CD2 
21  1 Y 1 B ARG 37  ? CZ  ? B ARG 37  CZ  
22  1 Y 1 B ARG 37  ? NH1 ? B ARG 37  NH1 
23  1 Y 1 B ARG 37  ? NH2 ? B ARG 37  NH2 
24  1 Y 1 B ARG 87  ? NE  ? B ARG 87  NE  
25  1 Y 1 B ARG 87  ? CZ  ? B ARG 87  CZ  
26  1 Y 1 B ARG 87  ? NH1 ? B ARG 87  NH1 
27  1 Y 1 B ARG 87  ? NH2 ? B ARG 87  NH2 
28  1 Y 1 B ARG 95  ? CZ  ? B ARG 95  CZ  
29  1 Y 1 B ARG 95  ? NH1 ? B ARG 95  NH1 
30  1 Y 1 B ARG 95  ? NH2 ? B ARG 95  NH2 
31  1 Y 1 B ARG 127 ? CD  ? B ARG 127 CD  
32  1 Y 1 B ARG 127 ? NE  ? B ARG 127 NE  
33  1 Y 1 B ARG 127 ? CZ  ? B ARG 127 CZ  
34  1 Y 1 B ARG 127 ? NH1 ? B ARG 127 NH1 
35  1 Y 1 B ARG 127 ? NH2 ? B ARG 127 NH2 
36  1 Y 1 B ARG 163 ? CZ  ? B ARG 163 CZ  
37  1 Y 1 B ARG 163 ? NH1 ? B ARG 163 NH1 
38  1 Y 1 B ARG 163 ? NH2 ? B ARG 163 NH2 
39  1 Y 1 B ARG 164 ? CG  ? B ARG 164 CG  
40  1 Y 1 B ARG 164 ? CD  ? B ARG 164 CD  
41  1 Y 1 B ARG 164 ? NE  ? B ARG 164 NE  
42  1 Y 1 B ARG 164 ? CZ  ? B ARG 164 CZ  
43  1 Y 1 B ARG 164 ? NH1 ? B ARG 164 NH1 
44  1 Y 1 B ARG 164 ? NH2 ? B ARG 164 NH2 
45  1 Y 1 B GLU 268 ? CD  ? B GLU 268 CD  
46  1 Y 1 B GLU 268 ? OE1 ? B GLU 268 OE1 
47  1 Y 1 B GLU 268 ? OE2 ? B GLU 268 OE2 
48  1 Y 1 B GLU 310 ? CD  ? B GLU 310 CD  
49  1 Y 1 B GLU 310 ? OE1 ? B GLU 310 OE1 
50  1 Y 1 B GLU 310 ? OE2 ? B GLU 310 OE2 
51  1 Y 1 C GLU 7   ? CG  ? C GLU 7   CG  
52  1 Y 1 C GLU 7   ? CD  ? C GLU 7   CD  
53  1 Y 1 C GLU 7   ? OE1 ? C GLU 7   OE1 
54  1 Y 1 C GLU 7   ? OE2 ? C GLU 7   OE2 
55  1 Y 1 C GLU 9   ? CD  ? C GLU 9   CD  
56  1 Y 1 C GLU 9   ? OE1 ? C GLU 9   OE1 
57  1 Y 1 C GLU 9   ? OE2 ? C GLU 9   OE2 
58  1 Y 1 C ARG 59  ? CZ  ? C ARG 59  CZ  
59  1 Y 1 C ARG 59  ? NH1 ? C ARG 59  NH1 
60  1 Y 1 C ARG 59  ? NH2 ? C ARG 59  NH2 
61  1 Y 1 C ARG 87  ? CG  ? C ARG 87  CG  
62  1 Y 1 C ARG 87  ? CD  ? C ARG 87  CD  
63  1 Y 1 C ARG 87  ? NE  ? C ARG 87  NE  
64  1 Y 1 C ARG 87  ? CZ  ? C ARG 87  CZ  
65  1 Y 1 C ARG 87  ? NH1 ? C ARG 87  NH1 
66  1 Y 1 C ARG 87  ? NH2 ? C ARG 87  NH2 
67  1 Y 1 C ARG 163 ? NE  ? C ARG 163 NE  
68  1 Y 1 C ARG 163 ? CZ  ? C ARG 163 CZ  
69  1 Y 1 C ARG 163 ? NH1 ? C ARG 163 NH1 
70  1 Y 1 C ARG 163 ? NH2 ? C ARG 163 NH2 
71  1 Y 1 C ASP 218 ? CG  ? C ASP 218 CG  
72  1 Y 1 C ASP 218 ? OD1 ? C ASP 218 OD1 
73  1 Y 1 C ASP 218 ? OD2 ? C ASP 218 OD2 
74  1 Y 1 C ASP 235 ? OD1 ? C ASP 235 OD1 
75  1 Y 1 C ASP 235 ? OD2 ? C ASP 235 OD2 
76  1 Y 1 C SER 237 ? OG  ? C SER 237 OG  
77  1 Y 1 C ARG 253 ? CZ  ? C ARG 253 CZ  
78  1 Y 1 C ARG 253 ? NH1 ? C ARG 253 NH1 
79  1 Y 1 C ARG 253 ? NH2 ? C ARG 253 NH2 
80  1 Y 1 C GLU 268 ? CD  ? C GLU 268 CD  
81  1 Y 1 C GLU 268 ? OE1 ? C GLU 268 OE1 
82  1 Y 1 C GLU 268 ? OE2 ? C GLU 268 OE2 
83  1 Y 1 D GLU 7   ? CG  ? D GLU 7   CG  
84  1 Y 1 D GLU 7   ? CD  ? D GLU 7   CD  
85  1 Y 1 D GLU 7   ? OE1 ? D GLU 7   OE1 
86  1 Y 1 D GLU 7   ? OE2 ? D GLU 7   OE2 
87  1 Y 1 D GLU 9   ? CD  ? D GLU 9   CD  
88  1 Y 1 D GLU 9   ? OE1 ? D GLU 9   OE1 
89  1 Y 1 D GLU 9   ? OE2 ? D GLU 9   OE2 
90  1 Y 1 D LEU 17  ? CG  ? D LEU 17  CG  
91  1 Y 1 D LEU 17  ? CD1 ? D LEU 17  CD1 
92  1 Y 1 D LEU 17  ? CD2 ? D LEU 17  CD2 
93  1 Y 1 D GLN 55  ? CD  ? D GLN 55  CD  
94  1 Y 1 D GLN 55  ? OE1 ? D GLN 55  OE1 
95  1 Y 1 D GLN 55  ? NE2 ? D GLN 55  NE2 
96  1 Y 1 D ASP 57  ? CG  ? D ASP 57  CG  
97  1 Y 1 D ASP 57  ? OD1 ? D ASP 57  OD1 
98  1 Y 1 D ASP 57  ? OD2 ? D ASP 57  OD2 
99  1 Y 1 D ARG 163 ? CZ  ? D ARG 163 CZ  
100 1 Y 1 D ARG 163 ? NH1 ? D ARG 163 NH1 
101 1 Y 1 D ARG 163 ? NH2 ? D ARG 163 NH2 
102 1 Y 1 D ARG 164 ? CD  ? D ARG 164 CD  
103 1 Y 1 D ARG 164 ? NE  ? D ARG 164 NE  
104 1 Y 1 D ARG 164 ? CZ  ? D ARG 164 CZ  
105 1 Y 1 D ARG 164 ? NH1 ? D ARG 164 NH1 
106 1 Y 1 D ARG 164 ? NH2 ? D ARG 164 NH2 
107 1 Y 1 D GLU 268 ? CD  ? D GLU 268 CD  
108 1 Y 1 D GLU 268 ? OE1 ? D GLU 268 OE1 
109 1 Y 1 D GLU 268 ? OE2 ? D GLU 268 OE2 
110 1 Y 1 D GLU 310 ? CG  ? D GLU 310 CG  
111 1 Y 1 D GLU 310 ? CD  ? D GLU 310 CD  
112 1 Y 1 D GLU 310 ? OE1 ? D GLU 310 OE1 
113 1 Y 1 D GLU 310 ? OE2 ? D GLU 310 OE2 
114 1 Y 1 E GLU 7   ? CG  ? E GLU 7   CG  
115 1 Y 1 E GLU 7   ? CD  ? E GLU 7   CD  
116 1 Y 1 E GLU 7   ? OE1 ? E GLU 7   OE1 
117 1 Y 1 E GLU 7   ? OE2 ? E GLU 7   OE2 
118 1 Y 1 E GLU 9   ? CG  ? E GLU 9   CG  
119 1 Y 1 E GLU 9   ? CD  ? E GLU 9   CD  
120 1 Y 1 E GLU 9   ? OE1 ? E GLU 9   OE1 
121 1 Y 1 E GLU 9   ? OE2 ? E GLU 9   OE2 
122 1 Y 1 E ARG 163 ? NE  ? E ARG 163 NE  
123 1 Y 1 E ARG 163 ? CZ  ? E ARG 163 CZ  
124 1 Y 1 E ARG 163 ? NH1 ? E ARG 163 NH1 
125 1 Y 1 E ARG 163 ? NH2 ? E ARG 163 NH2 
126 1 Y 1 E ARG 164 ? CD  ? E ARG 164 CD  
127 1 Y 1 E ARG 164 ? NE  ? E ARG 164 NE  
128 1 Y 1 E ARG 164 ? CZ  ? E ARG 164 CZ  
129 1 Y 1 E ARG 164 ? NH1 ? E ARG 164 NH1 
130 1 Y 1 E ARG 164 ? NH2 ? E ARG 164 NH2 
131 1 Y 1 E ASP 218 ? CG  ? E ASP 218 CG  
132 1 Y 1 E ASP 218 ? OD1 ? E ASP 218 OD1 
133 1 Y 1 E ASP 218 ? OD2 ? E ASP 218 OD2 
134 1 Y 1 E ASP 235 ? CG  ? E ASP 235 CG  
135 1 Y 1 E ASP 235 ? OD1 ? E ASP 235 OD1 
136 1 Y 1 E ASP 235 ? OD2 ? E ASP 235 OD2 
137 1 Y 1 E SER 237 ? OG  ? E SER 237 OG  
138 1 Y 1 E GLU 268 ? CD  ? E GLU 268 CD  
139 1 Y 1 E GLU 268 ? OE1 ? E GLU 268 OE1 
140 1 Y 1 E GLU 268 ? OE2 ? E GLU 268 OE2 
141 1 Y 1 F GLU 9   ? CG  ? F GLU 9   CG  
142 1 Y 1 F GLU 9   ? CD  ? F GLU 9   CD  
143 1 Y 1 F GLU 9   ? OE1 ? F GLU 9   OE1 
144 1 Y 1 F GLU 9   ? OE2 ? F GLU 9   OE2 
145 1 Y 1 F ARG 59  ? CZ  ? F ARG 59  CZ  
146 1 Y 1 F ARG 59  ? NH1 ? F ARG 59  NH1 
147 1 Y 1 F ARG 59  ? NH2 ? F ARG 59  NH2 
148 1 Y 1 F SER 76  ? OG  ? F SER 76  OG  
149 1 Y 1 F ARG 95  ? CZ  ? F ARG 95  CZ  
150 1 Y 1 F ARG 95  ? NH1 ? F ARG 95  NH1 
151 1 Y 1 F ARG 95  ? NH2 ? F ARG 95  NH2 
152 1 Y 1 F ARG 127 ? CG  ? F ARG 127 CG  
153 1 Y 1 F ARG 127 ? CD  ? F ARG 127 CD  
154 1 Y 1 F ARG 127 ? NE  ? F ARG 127 NE  
155 1 Y 1 F ARG 127 ? CZ  ? F ARG 127 CZ  
156 1 Y 1 F ARG 127 ? NH1 ? F ARG 127 NH1 
157 1 Y 1 F ARG 127 ? NH2 ? F ARG 127 NH2 
158 1 Y 1 F ARG 163 ? CD  ? F ARG 163 CD  
159 1 Y 1 F ARG 163 ? NE  ? F ARG 163 NE  
160 1 Y 1 F ARG 163 ? CZ  ? F ARG 163 CZ  
161 1 Y 1 F ARG 163 ? NH1 ? F ARG 163 NH1 
162 1 Y 1 F ARG 163 ? NH2 ? F ARG 163 NH2 
163 1 Y 1 F ASP 235 ? CG  ? F ASP 235 CG  
164 1 Y 1 F ASP 235 ? OD1 ? F ASP 235 OD1 
165 1 Y 1 F ASP 235 ? OD2 ? F ASP 235 OD2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FB7 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     86.891 
_cell.length_a_esd                 ? 
_cell.length_b                     121.924 
_cell.length_b_esd                 ? 
_cell.length_c                     199.572 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FB7 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FB7 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.61 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.89 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'6.2 mg/mL of protein in 20 mM NaPi, 150 mM NaCl pH 7 was mixed with 125 mM MgCl2, 125 mM HEPES, 18% PEG 4000 pH 7.5' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2019-09-19 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9686 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I24' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9686 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I24 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9FB7 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.02 
_reflns.d_resolution_low                               40.12 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     139296 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                85.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          1.6 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.9876 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   0.126 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.02 
_reflns_shell.d_res_low                                     2.07 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.5 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             9629 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.57 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  0.567 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.01 
_refine.aniso_B[1][2]                            0.00 
_refine.aniso_B[1][3]                            -0.00 
_refine.aniso_B[2][2]                            0.01 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            0.00 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               35.109 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.948 
_refine.correlation_coeff_Fo_to_Fc_free          0.929 
_refine.details                                  'HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9FB7 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.02 
_refine.ls_d_res_low                             40.12 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     132270 
_refine.ls_number_reflns_R_free                  6929 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.95 
_refine.ls_percent_reflns_R_free                 5.0 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.23019 
_refine.ls_R_factor_R_free                       0.25782 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.22874 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.203 
_refine.pdbx_overall_ESU_R_Free                  0.173 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             12.602 
_refine.overall_SU_ML                            0.288 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.02 
_refine_hist.d_res_low                        40.12 
_refine_hist.number_atoms_solvent             73 
_refine_hist.number_atoms_total               14146 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        13801 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         272 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.011  0.012  14425 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  13198 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 2.160  1.851  19689 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.727  1.753  30377 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 7.616  5.000  1829  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 12.958 5.000  119   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 15.527 10.000 2142  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.091  0.200  2167  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.009  0.020  17362 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.005  0.020  3342  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 3.814  3.341  7331  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 3.812  3.342  7331  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 5.770  5.986  9155  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 5.769  5.987  9156  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 4.908  3.693  7094  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 4.908  3.693  7093  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 7.401  6.596  10535 ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 8.873  30.30  15158 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 8.874  30.31  15154 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.020 
_refine_ls_shell.d_res_low                        2.072 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             503 
_refine_ls_shell.number_reflns_R_work             9629 
_refine_ls_shell.percent_reflns_obs               99.69 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.398 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.418 
# 
_struct.entry_id                     9FB7 
_struct.title                        'Dye-decolourising peroxidase DtpB (280 kGy)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FB7 
_struct_keywords.text            'Dye-decolourising peroxidase, heme peroxidase, oxidoreductase' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 2 ? 
H N N 3 ? 
I N N 2 ? 
J N N 2 ? 
K N N 2 ? 
L N N 4 ? 
M N N 2 ? 
N N N 2 ? 
O N N 5 ? 
P N N 5 ? 
Q N N 5 ? 
R N N 5 ? 
S N N 5 ? 
T N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A7U9HFU5_STRLI 
_struct_ref.pdbx_db_accession          A0A7U9HFU5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MGGEVEEPEPQMVLSPLTSAAIFLVVTIDSGGEDTVRDLLSDVASLERAVGFRAQPDGRLSCVTGIGSEAWDRLFSGARP
AGLHPFRELDGPVHRAVATPGDLLFHIRASRLDLCFALATEIMGRLRGAVTPQDEVHGFKYFDERDMLGFVDGTENPTGA
AARRAVLVGAEDPAFAGGSYAVVQKYLHDIDAWEGLSVEAQERVIGRRKMTDVELSDDVKPADSHVALTSVTGPDGSDLE
ILRDNMPFGSVGREEFGTYFIGYARTPEVTETMLERMFLGTASAPHDRILDFSTAVTGSLFFTPAADFLEDLS
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9FB7 A 1 ? 313 ? A0A7U9HFU5 1 ? 313 ? 1 313 
2 1 9FB7 B 1 ? 313 ? A0A7U9HFU5 1 ? 313 ? 1 313 
3 1 9FB7 C 1 ? 313 ? A0A7U9HFU5 1 ? 313 ? 1 313 
4 1 9FB7 D 1 ? 313 ? A0A7U9HFU5 1 ? 313 ? 1 313 
5 1 9FB7 E 1 ? 313 ? A0A7U9HFU5 1 ? 313 ? 1 313 
6 1 9FB7 F 1 ? 313 ? A0A7U9HFU5 1 ? 313 ? 1 313 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 22360 ? 
1 MORE         -236  ? 
1 'SSA (A^2)'  66190 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'equilibrium centrifugation' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 32  ? SER A 41  ? GLY A 32  SER A 41  1 ? 10 
HELX_P HELX_P2  AA2 ASP A 42  ? ARG A 53  ? ASP A 42  ARG A 53  1 ? 12 
HELX_P HELX_P3  AA3 GLY A 67  ? PHE A 75  ? GLY A 67  PHE A 75  1 ? 9  
HELX_P HELX_P4  AA4 ARG A 111 ? ARG A 127 ? ARG A 111 ARG A 127 1 ? 17 
HELX_P HELX_P5  AA5 THR A 158 ? LEU A 167 ? THR A 158 LEU A 167 1 ? 10 
HELX_P HELX_P6  AA6 ASP A 172 ? ALA A 176 ? ASP A 172 ALA A 176 5 ? 5  
HELX_P HELX_P7  AA7 ASP A 189 ? GLY A 195 ? ASP A 189 GLY A 195 1 ? 7  
HELX_P HELX_P8  AA8 SER A 197 ? GLY A 206 ? SER A 197 GLY A 206 1 ? 10 
HELX_P HELX_P9  AA9 SER A 224 ? THR A 229 ? SER A 224 THR A 229 1 ? 6  
HELX_P HELX_P10 AB1 THR A 266 ? GLY A 280 ? THR A 266 GLY A 280 1 ? 15 
HELX_P HELX_P11 AB2 ASP A 287 ? ASP A 291 ? ASP A 287 ASP A 291 5 ? 5  
HELX_P HELX_P12 AB3 ALA A 305 ? ASP A 311 ? ALA A 305 ASP A 311 1 ? 7  
HELX_P HELX_P13 AB4 GLY B 32  ? PHE B 52  ? GLY B 32  PHE B 52  1 ? 21 
HELX_P HELX_P14 AB5 ARG B 53  ? GLN B 55  ? ARG B 53  GLN B 55  5 ? 3  
HELX_P HELX_P15 AB6 GLY B 67  ? PHE B 75  ? GLY B 67  PHE B 75  1 ? 9  
HELX_P HELX_P16 AB7 ARG B 111 ? ARG B 127 ? ARG B 111 ARG B 127 1 ? 17 
HELX_P HELX_P17 AB8 THR B 158 ? LEU B 167 ? THR B 158 LEU B 167 1 ? 10 
HELX_P HELX_P18 AB9 ASP B 172 ? ALA B 176 ? ASP B 172 ALA B 176 5 ? 5  
HELX_P HELX_P19 AC1 ASP B 189 ? GLY B 195 ? ASP B 189 GLY B 195 1 ? 7  
HELX_P HELX_P20 AC2 SER B 197 ? GLY B 206 ? SER B 197 GLY B 206 1 ? 10 
HELX_P HELX_P21 AC3 SER B 224 ? THR B 229 ? SER B 224 THR B 229 1 ? 6  
HELX_P HELX_P22 AC4 THR B 266 ? GLY B 280 ? THR B 266 GLY B 280 1 ? 15 
HELX_P HELX_P23 AC5 ASP B 287 ? ASP B 291 ? ASP B 287 ASP B 291 5 ? 5  
HELX_P HELX_P24 AC6 ALA B 305 ? ASP B 311 ? ALA B 305 ASP B 311 1 ? 7  
HELX_P HELX_P25 AC7 GLY C 32  ? PHE C 52  ? GLY C 32  PHE C 52  1 ? 21 
HELX_P HELX_P26 AC8 ARG C 53  ? GLN C 55  ? ARG C 53  GLN C 55  5 ? 3  
HELX_P HELX_P27 AC9 GLY C 67  ? PHE C 75  ? GLY C 67  PHE C 75  1 ? 9  
HELX_P HELX_P28 AD1 ARG C 111 ? ARG C 127 ? ARG C 111 ARG C 127 1 ? 17 
HELX_P HELX_P29 AD2 THR C 158 ? LEU C 167 ? THR C 158 LEU C 167 1 ? 10 
HELX_P HELX_P30 AD3 ASP C 172 ? ALA C 176 ? ASP C 172 ALA C 176 5 ? 5  
HELX_P HELX_P31 AD4 ASP C 189 ? GLY C 195 ? ASP C 189 GLY C 195 1 ? 7  
HELX_P HELX_P32 AD5 SER C 197 ? GLY C 206 ? SER C 197 GLY C 206 1 ? 10 
HELX_P HELX_P33 AD6 SER C 224 ? SER C 230 ? SER C 224 SER C 230 1 ? 7  
HELX_P HELX_P34 AD7 THR C 266 ? GLY C 280 ? THR C 266 GLY C 280 1 ? 15 
HELX_P HELX_P35 AD8 ASP C 287 ? ASP C 291 ? ASP C 287 ASP C 291 5 ? 5  
HELX_P HELX_P36 AD9 ALA C 305 ? ASP C 311 ? ALA C 305 ASP C 311 1 ? 7  
HELX_P HELX_P37 AE1 GLY D 32  ? ARG D 53  ? GLY D 32  ARG D 53  1 ? 22 
HELX_P HELX_P38 AE2 GLY D 67  ? PHE D 75  ? GLY D 67  PHE D 75  1 ? 9  
HELX_P HELX_P39 AE3 ARG D 111 ? ARG D 127 ? ARG D 111 ARG D 127 1 ? 17 
HELX_P HELX_P40 AE4 THR D 158 ? LEU D 167 ? THR D 158 LEU D 167 1 ? 10 
HELX_P HELX_P41 AE5 ASP D 172 ? ALA D 176 ? ASP D 172 ALA D 176 5 ? 5  
HELX_P HELX_P42 AE6 ASP D 189 ? GLY D 195 ? ASP D 189 GLY D 195 1 ? 7  
HELX_P HELX_P43 AE7 SER D 197 ? GLY D 206 ? SER D 197 GLY D 206 1 ? 10 
HELX_P HELX_P44 AE8 SER D 224 ? THR D 229 ? SER D 224 THR D 229 1 ? 6  
HELX_P HELX_P45 AE9 THR D 266 ? GLY D 280 ? THR D 266 GLY D 280 1 ? 15 
HELX_P HELX_P46 AF1 ASP D 287 ? ASP D 291 ? ASP D 287 ASP D 291 5 ? 5  
HELX_P HELX_P47 AF2 ALA D 305 ? ASP D 311 ? ALA D 305 ASP D 311 1 ? 7  
HELX_P HELX_P48 AF3 GLY E 32  ? PHE E 52  ? GLY E 32  PHE E 52  1 ? 21 
HELX_P HELX_P49 AF4 ARG E 53  ? GLN E 55  ? ARG E 53  GLN E 55  5 ? 3  
HELX_P HELX_P50 AF5 GLY E 67  ? PHE E 75  ? GLY E 67  PHE E 75  1 ? 9  
HELX_P HELX_P51 AF6 ARG E 111 ? ARG E 127 ? ARG E 111 ARG E 127 1 ? 17 
HELX_P HELX_P52 AF7 THR E 158 ? LEU E 167 ? THR E 158 LEU E 167 1 ? 10 
HELX_P HELX_P53 AF8 ASP E 172 ? ALA E 176 ? ASP E 172 ALA E 176 5 ? 5  
HELX_P HELX_P54 AF9 ASP E 189 ? GLY E 195 ? ASP E 189 GLY E 195 1 ? 7  
HELX_P HELX_P55 AG1 SER E 197 ? GLY E 206 ? SER E 197 GLY E 206 1 ? 10 
HELX_P HELX_P56 AG2 SER E 224 ? THR E 229 ? SER E 224 THR E 229 1 ? 6  
HELX_P HELX_P57 AG3 THR E 266 ? GLY E 280 ? THR E 266 GLY E 280 1 ? 15 
HELX_P HELX_P58 AG4 ASP E 287 ? ASP E 291 ? ASP E 287 ASP E 291 5 ? 5  
HELX_P HELX_P59 AG5 ALA E 305 ? ASP E 311 ? ALA E 305 ASP E 311 1 ? 7  
HELX_P HELX_P60 AG6 GLY F 32  ? ARG F 53  ? GLY F 32  ARG F 53  1 ? 22 
HELX_P HELX_P61 AG7 GLY F 67  ? PHE F 75  ? GLY F 67  PHE F 75  1 ? 9  
HELX_P HELX_P62 AG8 ARG F 111 ? ARG F 127 ? ARG F 111 ARG F 127 1 ? 17 
HELX_P HELX_P63 AG9 THR F 158 ? LEU F 167 ? THR F 158 LEU F 167 1 ? 10 
HELX_P HELX_P64 AH1 ASP F 172 ? ALA F 176 ? ASP F 172 ALA F 176 5 ? 5  
HELX_P HELX_P65 AH2 ASP F 189 ? GLY F 195 ? ASP F 189 GLY F 195 1 ? 7  
HELX_P HELX_P66 AH3 SER F 197 ? GLY F 206 ? SER F 197 GLY F 206 1 ? 10 
HELX_P HELX_P67 AH4 SER F 224 ? THR F 229 ? SER F 224 THR F 229 1 ? 6  
HELX_P HELX_P68 AH5 THR F 266 ? GLY F 280 ? THR F 266 GLY F 280 1 ? 15 
HELX_P HELX_P69 AH6 ASP F 287 ? ASP F 291 ? ASP F 287 ASP F 291 5 ? 5  
HELX_P HELX_P70 AH7 ALA F 305 ? ASP F 311 ? ALA F 305 ASP F 311 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A ASP 191 OD2 ? ? ? 1_555 H MG  . MG ? ? A ASP 191 A MG  402 1_555 ? ? ? ? ? ? ? 2.145 ? ? 
metalc2  metalc ? ? A HIS 225 NE2 ? ? ? 1_555 G HEM . FE ? ? A HIS 225 A HEM 401 1_555 ? ? ? ? ? ? ? 2.084 ? ? 
metalc3  metalc ? ? G HEM .   FE  ? ? ? 1_555 O HOH . O  ? ? A HEM 401 A HOH 504 1_555 ? ? ? ? ? ? ? 1.917 ? ? 
metalc4  metalc ? ? H MG  .   MG  ? ? ? 1_555 O HOH . O  ? ? A MG  402 A HOH 502 1_555 ? ? ? ? ? ? ? 2.132 ? ? 
metalc5  metalc ? ? H MG  .   MG  ? ? ? 1_555 O HOH . O  ? ? A MG  402 A HOH 514 1_555 ? ? ? ? ? ? ? 2.212 ? ? 
metalc6  metalc ? ? H MG  .   MG  ? ? ? 1_555 O HOH . O  ? ? A MG  402 A HOH 518 1_555 ? ? ? ? ? ? ? 2.136 ? ? 
metalc7  metalc ? ? H MG  .   MG  ? ? ? 1_555 R HOH . O  ? ? A MG  402 D HOH 514 4_455 ? ? ? ? ? ? ? 2.005 ? ? 
metalc8  metalc ? ? H MG  .   MG  ? ? ? 1_555 R HOH . O  ? ? A MG  402 D HOH 515 4_455 ? ? ? ? ? ? ? 1.767 ? ? 
metalc9  metalc ? ? B HIS 225 NE2 ? ? ? 1_555 I HEM . FE ? ? B HIS 225 B HEM 401 1_555 ? ? ? ? ? ? ? 2.102 ? ? 
metalc10 metalc ? ? C HIS 225 NE2 ? ? ? 1_555 J HEM . FE ? ? C HIS 225 C HEM 401 1_555 ? ? ? ? ? ? ? 2.196 ? ? 
metalc11 metalc ? ? J HEM .   FE  ? ? ? 1_555 Q HOH . O  ? ? C HEM 401 C HOH 501 1_555 ? ? ? ? ? ? ? 2.521 ? ? 
metalc12 metalc ? ? D HIS 225 NE2 ? ? ? 1_555 K HEM . FE ? ? D HIS 225 D HEM 401 1_555 ? ? ? ? ? ? ? 2.125 ? ? 
metalc13 metalc ? ? K HEM .   FE  ? ? ? 1_555 R HOH . O  ? ? D HEM 401 D HOH 501 1_555 ? ? ? ? ? ? ? 2.094 ? ? 
metalc14 metalc ? ? E HIS 225 NE2 ? ? ? 1_555 M HEM . FE ? ? E HIS 225 E HEM 401 1_555 ? ? ? ? ? ? ? 2.123 ? ? 
metalc15 metalc ? ? F HIS 225 NE2 ? ? ? 1_555 N HEM . FE ? ? F HIS 225 F HEM 401 1_555 ? ? ? ? ? ? ? 2.098 ? ? 
metalc16 metalc ? ? N HEM .   FE  ? ? ? 1_555 T HOH . O  ? ? F HEM 401 F HOH 503 1_555 ? ? ? ? ? ? ? 2.233 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? O HOH . ? A HOH 502 ? 1_555 77.8  ? 
2  OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? O HOH . ? A HOH 514 ? 1_555 83.9  ? 
3  O   ? O HOH .   ? A HOH 502 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? O HOH . ? A HOH 514 ? 1_555 84.9  ? 
4  OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? O HOH . ? A HOH 518 ? 1_555 81.7  ? 
5  O   ? O HOH .   ? A HOH 502 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? O HOH . ? A HOH 518 ? 1_555 86.4  ? 
6  O   ? O HOH .   ? A HOH 514 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? O HOH . ? A HOH 518 ? 1_555 164.5 ? 
7  OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? D HOH 514 ? 4_455 108.8 ? 
8  O   ? O HOH .   ? A HOH 502 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? D HOH 514 ? 4_455 164.5 ? 
9  O   ? O HOH .   ? A HOH 514 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? D HOH 514 ? 4_455 81.9  ? 
10 O   ? O HOH .   ? A HOH 518 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? D HOH 514 ? 4_455 108.2 ? 
11 OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? D HOH 515 ? 4_455 160.7 ? 
12 O   ? O HOH .   ? A HOH 502 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? D HOH 515 ? 4_455 82.9  ? 
13 O   ? O HOH .   ? A HOH 514 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? D HOH 515 ? 4_455 96.0  ? 
14 O   ? O HOH .   ? A HOH 518 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? D HOH 515 ? 4_455 95.7  ? 
15 O   ? R HOH .   ? D HOH 514 ? 4_455 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? D HOH 515 ? 4_455 90.2  ? 
16 NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NA ? G HEM . ? A HEM 401 ? 1_555 93.5  ? 
17 NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NB ? G HEM . ? A HEM 401 ? 1_555 90.9  ? 
18 NA  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NB ? G HEM . ? A HEM 401 ? 1_555 87.1  ? 
19 NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NC ? G HEM . ? A HEM 401 ? 1_555 95.1  ? 
20 NA  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NC ? G HEM . ? A HEM 401 ? 1_555 169.0 ? 
21 NB  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NC ? G HEM . ? A HEM 401 ? 1_555 85.9  ? 
22 NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 ND ? G HEM . ? A HEM 401 ? 1_555 94.8  ? 
23 NA  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 ND ? G HEM . ? A HEM 401 ? 1_555 93.2  ? 
24 NB  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 ND ? G HEM . ? A HEM 401 ? 1_555 174.2 ? 
25 NC  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 ND ? G HEM . ? A HEM 401 ? 1_555 92.9  ? 
26 NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? O HOH . ? A HOH 504 ? 1_555 166.0 ? 
27 NA  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? O HOH . ? A HOH 504 ? 1_555 88.1  ? 
28 NB  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? O HOH . ? A HOH 504 ? 1_555 75.2  ? 
29 NC  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? O HOH . ? A HOH 504 ? 1_555 82.0  ? 
30 ND  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? O HOH . ? A HOH 504 ? 1_555 99.0  ? 
31 NE2 ? B HIS 225 ? B HIS 225 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 NA ? I HEM . ? B HEM 401 ? 1_555 90.8  ? 
32 NE2 ? B HIS 225 ? B HIS 225 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 NB ? I HEM . ? B HEM 401 ? 1_555 90.3  ? 
33 NA  ? I HEM .   ? B HEM 401 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 NB ? I HEM . ? B HEM 401 ? 1_555 86.9  ? 
34 NE2 ? B HIS 225 ? B HIS 225 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 NC ? I HEM . ? B HEM 401 ? 1_555 92.7  ? 
35 NA  ? I HEM .   ? B HEM 401 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 NC ? I HEM . ? B HEM 401 ? 1_555 173.0 ? 
36 NB  ? I HEM .   ? B HEM 401 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 NC ? I HEM . ? B HEM 401 ? 1_555 87.0  ? 
37 NE2 ? B HIS 225 ? B HIS 225 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 ND ? I HEM . ? B HEM 401 ? 1_555 93.8  ? 
38 NA  ? I HEM .   ? B HEM 401 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 ND ? I HEM . ? B HEM 401 ? 1_555 90.4  ? 
39 NB  ? I HEM .   ? B HEM 401 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 ND ? I HEM . ? B HEM 401 ? 1_555 175.2 ? 
40 NC  ? I HEM .   ? B HEM 401 ? 1_555 FE ? I HEM . ? B HEM 401 ? 1_555 ND ? I HEM . ? B HEM 401 ? 1_555 95.4  ? 
41 NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 NA ? J HEM . ? C HEM 401 ? 1_555 94.4  ? 
42 NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 NB ? J HEM . ? C HEM 401 ? 1_555 90.1  ? 
43 NA  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 NB ? J HEM . ? C HEM 401 ? 1_555 86.3  ? 
44 NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 NC ? J HEM . ? C HEM 401 ? 1_555 92.7  ? 
45 NA  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 NC ? J HEM . ? C HEM 401 ? 1_555 170.9 ? 
46 NB  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 NC ? J HEM . ? C HEM 401 ? 1_555 88.0  ? 
47 NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 ND ? J HEM . ? C HEM 401 ? 1_555 94.7  ? 
48 NA  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 ND ? J HEM . ? C HEM 401 ? 1_555 93.8  ? 
49 NB  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 ND ? J HEM . ? C HEM 401 ? 1_555 175.1 ? 
50 NC  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 ND ? J HEM . ? C HEM 401 ? 1_555 91.3  ? 
51 NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 O  ? Q HOH . ? C HOH 501 ? 1_555 168.3 ? 
52 NA  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 O  ? Q HOH . ? C HOH 501 ? 1_555 89.8  ? 
53 NB  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 O  ? Q HOH . ? C HOH 501 ? 1_555 79.2  ? 
54 NC  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 O  ? Q HOH . ? C HOH 501 ? 1_555 82.2  ? 
55 ND  ? J HEM .   ? C HEM 401 ? 1_555 FE ? J HEM . ? C HEM 401 ? 1_555 O  ? Q HOH . ? C HOH 501 ? 1_555 95.9  ? 
56 NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 NA ? K HEM . ? D HEM 401 ? 1_555 92.7  ? 
57 NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 NB ? K HEM . ? D HEM 401 ? 1_555 91.5  ? 
58 NA  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 NB ? K HEM . ? D HEM 401 ? 1_555 87.7  ? 
59 NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 NC ? K HEM . ? D HEM 401 ? 1_555 96.7  ? 
60 NA  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 NC ? K HEM . ? D HEM 401 ? 1_555 170.2 ? 
61 NB  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 NC ? K HEM . ? D HEM 401 ? 1_555 89.5  ? 
62 NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 ND ? K HEM . ? D HEM 401 ? 1_555 93.0  ? 
63 NA  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 ND ? K HEM . ? D HEM 401 ? 1_555 90.2  ? 
64 NB  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 ND ? K HEM . ? D HEM 401 ? 1_555 175.0 ? 
65 NC  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 ND ? K HEM . ? D HEM 401 ? 1_555 91.8  ? 
66 NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 O  ? R HOH . ? D HOH 501 ? 1_555 171.1 ? 
67 NA  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 O  ? R HOH . ? D HOH 501 ? 1_555 96.1  ? 
68 NB  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 O  ? R HOH . ? D HOH 501 ? 1_555 89.2  ? 
69 NC  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 O  ? R HOH . ? D HOH 501 ? 1_555 74.5  ? 
70 ND  ? K HEM .   ? D HEM 401 ? 1_555 FE ? K HEM . ? D HEM 401 ? 1_555 O  ? R HOH . ? D HOH 501 ? 1_555 86.5  ? 
71 NE2 ? E HIS 225 ? E HIS 225 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 NA ? M HEM . ? E HEM 401 ? 1_555 92.1  ? 
72 NE2 ? E HIS 225 ? E HIS 225 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 NB ? M HEM . ? E HEM 401 ? 1_555 91.0  ? 
73 NA  ? M HEM .   ? E HEM 401 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 NB ? M HEM . ? E HEM 401 ? 1_555 92.5  ? 
74 NE2 ? E HIS 225 ? E HIS 225 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 NC ? M HEM . ? E HEM 401 ? 1_555 92.8  ? 
75 NA  ? M HEM .   ? E HEM 401 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 NC ? M HEM . ? E HEM 401 ? 1_555 174.2 ? 
76 NB  ? M HEM .   ? E HEM 401 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 NC ? M HEM . ? E HEM 401 ? 1_555 90.4  ? 
77 NE2 ? E HIS 225 ? E HIS 225 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 ND ? M HEM . ? E HEM 401 ? 1_555 91.5  ? 
78 NA  ? M HEM .   ? E HEM 401 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 ND ? M HEM . ? E HEM 401 ? 1_555 87.6  ? 
79 NB  ? M HEM .   ? E HEM 401 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 ND ? M HEM . ? E HEM 401 ? 1_555 177.5 ? 
80 NC  ? M HEM .   ? E HEM 401 ? 1_555 FE ? M HEM . ? E HEM 401 ? 1_555 ND ? M HEM . ? E HEM 401 ? 1_555 89.3  ? 
81 NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 NA ? N HEM . ? F HEM 401 ? 1_555 90.9  ? 
82 NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 NB ? N HEM . ? F HEM 401 ? 1_555 91.9  ? 
83 NA  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 NB ? N HEM . ? F HEM 401 ? 1_555 87.6  ? 
84 NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 NC ? N HEM . ? F HEM 401 ? 1_555 96.8  ? 
85 NA  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 NC ? N HEM . ? F HEM 401 ? 1_555 171.4 ? 
86 NB  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 NC ? N HEM . ? F HEM 401 ? 1_555 88.3  ? 
87 NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 ND ? N HEM . ? F HEM 401 ? 1_555 92.4  ? 
88 NA  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 ND ? N HEM . ? F HEM 401 ? 1_555 93.6  ? 
89 NB  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 ND ? N HEM . ? F HEM 401 ? 1_555 175.5 ? 
90 NC  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 ND ? N HEM . ? F HEM 401 ? 1_555 89.8  ? 
91 NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 O  ? T HOH . ? F HOH 503 ? 1_555 172.3 ? 
92 NA  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 O  ? T HOH . ? F HOH 503 ? 1_555 86.5  ? 
93 NB  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 O  ? T HOH . ? F HOH 503 ? 1_555 80.8  ? 
94 NC  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 O  ? T HOH . ? F HOH 503 ? 1_555 85.4  ? 
95 ND  ? N HEM .   ? F HEM 401 ? 1_555 FE ? N HEM . ? F HEM 401 ? 1_555 O  ? T HOH . ? F HOH 503 ? 1_555 95.0  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 55 A . ? GLN 55 A PRO 56 A ? PRO 56 A 1 -8.19  
2 GLN 55 B . ? GLN 55 B PRO 56 B ? PRO 56 B 1 -10.06 
3 GLN 55 C . ? GLN 55 C PRO 56 C ? PRO 56 C 1 -4.62  
4 GLN 55 D . ? GLN 55 D PRO 56 D ? PRO 56 D 1 -12.20 
5 GLN 55 E . ? GLN 55 E PRO 56 E ? PRO 56 E 1 -10.36 
6 GLN 55 F . ? GLN 55 F PRO 56 F ? PRO 56 F 1 -4.54  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 2 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
AB2 ? 4 ? 
AB3 ? 2 ? 
AB4 ? 4 ? 
AB5 ? 4 ? 
AB6 ? 4 ? 
AB7 ? 2 ? 
AB8 ? 4 ? 
AB9 ? 4 ? 
AC1 ? 4 ? 
AC2 ? 2 ? 
AC3 ? 4 ? 
AC4 ? 4 ? 
AC5 ? 4 ? 
AC6 ? 2 ? 
AC7 ? 4 ? 
AC8 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC8 2 3 ? anti-parallel 
AC8 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 61  ? ILE A 66  ? SER A 61  ILE A 66  
AA1 2 LEU A 103 ? ALA A 109 ? LEU A 103 ALA A 109 
AA1 3 ALA A 20  ? ILE A 28  ? ALA A 20  ILE A 28  
AA1 4 VAL A 130 ? PHE A 139 ? VAL A 130 PHE A 139 
AA2 1 LEU A 89  ? ASP A 90  ? LEU A 89  ASP A 90  
AA2 2 ARG A 95  ? ALA A 96  ? ARG A 95  ALA A 96  
AA3 1 LEU A 242 ? ARG A 243 ? LEU A 242 ARG A 243 
AA3 2 GLU A 255 ? ALA A 264 ? GLU A 255 ALA A 264 
AA3 3 SER A 179 ? HIS A 188 ? SER A 179 HIS A 188 
AA3 4 SER A 293 ? ALA A 295 ? SER A 293 ALA A 295 
AA4 1 MET A 246 ? SER A 250 ? MET A 246 SER A 250 
AA4 2 GLU A 255 ? ALA A 264 ? GLU A 255 ALA A 264 
AA4 3 SER A 179 ? HIS A 188 ? SER A 179 HIS A 188 
AA4 4 SER A 299 ? THR A 303 ? SER A 299 THR A 303 
AA5 1 VAL A 231 ? THR A 232 ? VAL A 231 THR A 232 
AA5 2 ASP A 238 ? LEU A 239 ? ASP A 238 LEU A 239 
AA6 1 SER B 61  ? ILE B 66  ? SER B 61  ILE B 66  
AA6 2 LEU B 103 ? ALA B 109 ? LEU B 103 ALA B 109 
AA6 3 ALA B 20  ? ILE B 28  ? ALA B 20  ILE B 28  
AA6 4 VAL B 130 ? PHE B 139 ? VAL B 130 PHE B 139 
AA7 1 LEU B 89  ? ASP B 90  ? LEU B 89  ASP B 90  
AA7 2 ARG B 95  ? ALA B 96  ? ARG B 95  ALA B 96  
AA8 1 LEU B 242 ? ARG B 243 ? LEU B 242 ARG B 243 
AA8 2 GLU B 255 ? ALA B 264 ? GLU B 255 ALA B 264 
AA8 3 SER B 179 ? HIS B 188 ? SER B 179 HIS B 188 
AA8 4 SER B 293 ? ALA B 295 ? SER B 293 ALA B 295 
AA9 1 MET B 246 ? SER B 250 ? MET B 246 SER B 250 
AA9 2 GLU B 255 ? ALA B 264 ? GLU B 255 ALA B 264 
AA9 3 SER B 179 ? HIS B 188 ? SER B 179 HIS B 188 
AA9 4 SER B 299 ? THR B 303 ? SER B 299 THR B 303 
AB1 1 VAL B 231 ? THR B 232 ? VAL B 231 THR B 232 
AB1 2 ASP B 238 ? LEU B 239 ? ASP B 238 LEU B 239 
AB2 1 SER C 61  ? ILE C 66  ? SER C 61  ILE C 66  
AB2 2 LEU C 103 ? ALA C 109 ? LEU C 103 ALA C 109 
AB2 3 ALA C 20  ? ILE C 28  ? ALA C 20  ILE C 28  
AB2 4 VAL C 130 ? PHE C 139 ? VAL C 130 PHE C 139 
AB3 1 LEU C 89  ? ASP C 90  ? LEU C 89  ASP C 90  
AB3 2 ARG C 95  ? ALA C 96  ? ARG C 95  ALA C 96  
AB4 1 LEU C 242 ? ARG C 243 ? LEU C 242 ARG C 243 
AB4 2 GLU C 255 ? ALA C 264 ? GLU C 255 ALA C 264 
AB4 3 SER C 179 ? HIS C 188 ? SER C 179 HIS C 188 
AB4 4 SER C 293 ? ALA C 295 ? SER C 293 ALA C 295 
AB5 1 MET C 246 ? SER C 250 ? MET C 246 SER C 250 
AB5 2 GLU C 255 ? ALA C 264 ? GLU C 255 ALA C 264 
AB5 3 SER C 179 ? HIS C 188 ? SER C 179 HIS C 188 
AB5 4 SER C 299 ? THR C 303 ? SER C 299 THR C 303 
AB6 1 SER D 61  ? ILE D 66  ? SER D 61  ILE D 66  
AB6 2 LEU D 103 ? ALA D 109 ? LEU D 103 ALA D 109 
AB6 3 ALA D 20  ? ILE D 28  ? ALA D 20  ILE D 28  
AB6 4 VAL D 130 ? PHE D 139 ? VAL D 130 PHE D 139 
AB7 1 LEU D 89  ? ASP D 90  ? LEU D 89  ASP D 90  
AB7 2 ARG D 95  ? ALA D 96  ? ARG D 95  ALA D 96  
AB8 1 LEU D 242 ? ARG D 243 ? LEU D 242 ARG D 243 
AB8 2 GLU D 255 ? ALA D 264 ? GLU D 255 ALA D 264 
AB8 3 SER D 179 ? HIS D 188 ? SER D 179 HIS D 188 
AB8 4 SER D 293 ? ALA D 295 ? SER D 293 ALA D 295 
AB9 1 MET D 246 ? SER D 250 ? MET D 246 SER D 250 
AB9 2 GLU D 255 ? ALA D 264 ? GLU D 255 ALA D 264 
AB9 3 SER D 179 ? HIS D 188 ? SER D 179 HIS D 188 
AB9 4 SER D 299 ? THR D 303 ? SER D 299 THR D 303 
AC1 1 SER E 61  ? ILE E 66  ? SER E 61  ILE E 66  
AC1 2 LEU E 103 ? ALA E 109 ? LEU E 103 ALA E 109 
AC1 3 ALA E 20  ? ILE E 28  ? ALA E 20  ILE E 28  
AC1 4 VAL E 130 ? PHE E 139 ? VAL E 130 PHE E 139 
AC2 1 LEU E 89  ? ASP E 90  ? LEU E 89  ASP E 90  
AC2 2 ARG E 95  ? ALA E 96  ? ARG E 95  ALA E 96  
AC3 1 LEU E 242 ? ARG E 243 ? LEU E 242 ARG E 243 
AC3 2 GLU E 255 ? ALA E 264 ? GLU E 255 ALA E 264 
AC3 3 SER E 179 ? HIS E 188 ? SER E 179 HIS E 188 
AC3 4 SER E 293 ? ALA E 295 ? SER E 293 ALA E 295 
AC4 1 MET E 246 ? SER E 250 ? MET E 246 SER E 250 
AC4 2 GLU E 255 ? ALA E 264 ? GLU E 255 ALA E 264 
AC4 3 SER E 179 ? HIS E 188 ? SER E 179 HIS E 188 
AC4 4 SER E 299 ? THR E 303 ? SER E 299 THR E 303 
AC5 1 SER F 61  ? ILE F 66  ? SER F 61  ILE F 66  
AC5 2 LEU F 103 ? ALA F 109 ? LEU F 103 ALA F 109 
AC5 3 ALA F 20  ? ILE F 28  ? ALA F 20  ILE F 28  
AC5 4 VAL F 130 ? PHE F 139 ? VAL F 130 PHE F 139 
AC6 1 LEU F 89  ? ASP F 90  ? LEU F 89  ASP F 90  
AC6 2 ARG F 95  ? ALA F 96  ? ARG F 95  ALA F 96  
AC7 1 LEU F 242 ? ARG F 243 ? LEU F 242 ARG F 243 
AC7 2 GLU F 255 ? ALA F 264 ? GLU F 255 ALA F 264 
AC7 3 SER F 179 ? HIS F 188 ? SER F 179 HIS F 188 
AC7 4 SER F 293 ? ALA F 295 ? SER F 293 ALA F 295 
AC8 1 MET F 246 ? SER F 250 ? MET F 246 SER F 250 
AC8 2 GLU F 255 ? ALA F 264 ? GLU F 255 ALA F 264 
AC8 3 SER F 179 ? HIS F 188 ? SER F 179 HIS F 188 
AC8 4 SER F 299 ? THR F 303 ? SER F 299 THR F 303 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 63  ? N VAL A 63  O HIS A 106 ? O HIS A 106 
AA1 2 3 O ILE A 107 ? O ILE A 107 N ILE A 22  ? N ILE A 22  
AA1 3 4 N VAL A 25  ? N VAL A 25  O GLN A 133 ? O GLN A 133 
AA2 1 2 N LEU A 89  ? N LEU A 89  O ALA A 96  ? O ALA A 96  
AA3 1 2 N LEU A 242 ? N LEU A 242 O TYR A 263 ? O TYR A 263 
AA3 2 3 O PHE A 256 ? O PHE A 256 N HIS A 188 ? N HIS A 188 
AA3 3 4 N LEU A 187 ? N LEU A 187 O THR A 294 ? O THR A 294 
AA4 1 2 N MET A 246 ? N MET A 246 O TYR A 259 ? O TYR A 259 
AA4 2 3 O PHE A 256 ? O PHE A 256 N HIS A 188 ? N HIS A 188 
AA4 3 4 N SER A 179 ? N SER A 179 O THR A 303 ? O THR A 303 
AA5 1 2 N VAL A 231 ? N VAL A 231 O LEU A 239 ? O LEU A 239 
AA6 1 2 N VAL B 63  ? N VAL B 63  O HIS B 106 ? O HIS B 106 
AA6 2 3 O ILE B 107 ? O ILE B 107 N ILE B 22  ? N ILE B 22  
AA6 3 4 N VAL B 25  ? N VAL B 25  O GLN B 133 ? O GLN B 133 
AA7 1 2 N LEU B 89  ? N LEU B 89  O ALA B 96  ? O ALA B 96  
AA8 1 2 N LEU B 242 ? N LEU B 242 O TYR B 263 ? O TYR B 263 
AA8 2 3 O PHE B 256 ? O PHE B 256 N HIS B 188 ? N HIS B 188 
AA8 3 4 N LEU B 187 ? N LEU B 187 O THR B 294 ? O THR B 294 
AA9 1 2 N MET B 246 ? N MET B 246 O TYR B 259 ? O TYR B 259 
AA9 2 3 O PHE B 256 ? O PHE B 256 N HIS B 188 ? N HIS B 188 
AA9 3 4 N SER B 179 ? N SER B 179 O THR B 303 ? O THR B 303 
AB1 1 2 N VAL B 231 ? N VAL B 231 O LEU B 239 ? O LEU B 239 
AB2 1 2 N GLY C 65  ? N GLY C 65  O LEU C 104 ? O LEU C 104 
AB2 2 3 O ILE C 107 ? O ILE C 107 N ILE C 22  ? N ILE C 22  
AB2 3 4 N VAL C 25  ? N VAL C 25  O GLN C 133 ? O GLN C 133 
AB3 1 2 N LEU C 89  ? N LEU C 89  O ALA C 96  ? O ALA C 96  
AB4 1 2 N LEU C 242 ? N LEU C 242 O TYR C 263 ? O TYR C 263 
AB4 2 3 O PHE C 256 ? O PHE C 256 N HIS C 188 ? N HIS C 188 
AB4 3 4 N LEU C 187 ? N LEU C 187 O THR C 294 ? O THR C 294 
AB5 1 2 N MET C 246 ? N MET C 246 O TYR C 259 ? O TYR C 259 
AB5 2 3 O PHE C 256 ? O PHE C 256 N HIS C 188 ? N HIS C 188 
AB5 3 4 N SER C 179 ? N SER C 179 O THR C 303 ? O THR C 303 
AB6 1 2 N VAL D 63  ? N VAL D 63  O HIS D 106 ? O HIS D 106 
AB6 2 3 O ILE D 107 ? O ILE D 107 N ILE D 22  ? N ILE D 22  
AB6 3 4 N VAL D 25  ? N VAL D 25  O GLN D 133 ? O GLN D 133 
AB7 1 2 N LEU D 89  ? N LEU D 89  O ALA D 96  ? O ALA D 96  
AB8 1 2 N LEU D 242 ? N LEU D 242 O TYR D 263 ? O TYR D 263 
AB8 2 3 O PHE D 260 ? O PHE D 260 N GLN D 184 ? N GLN D 184 
AB8 3 4 N LEU D 187 ? N LEU D 187 O THR D 294 ? O THR D 294 
AB9 1 2 N MET D 246 ? N MET D 246 O TYR D 259 ? O TYR D 259 
AB9 2 3 O PHE D 260 ? O PHE D 260 N GLN D 184 ? N GLN D 184 
AB9 3 4 N SER D 179 ? N SER D 179 O THR D 303 ? O THR D 303 
AC1 1 2 N VAL E 63  ? N VAL E 63  O HIS E 106 ? O HIS E 106 
AC1 2 3 O ILE E 107 ? O ILE E 107 N ILE E 22  ? N ILE E 22  
AC1 3 4 N VAL E 25  ? N VAL E 25  O GLN E 133 ? O GLN E 133 
AC2 1 2 N LEU E 89  ? N LEU E 89  O ALA E 96  ? O ALA E 96  
AC3 1 2 N LEU E 242 ? N LEU E 242 O TYR E 263 ? O TYR E 263 
AC3 2 3 O PHE E 260 ? O PHE E 260 N GLN E 184 ? N GLN E 184 
AC3 3 4 N LEU E 187 ? N LEU E 187 O THR E 294 ? O THR E 294 
AC4 1 2 N MET E 246 ? N MET E 246 O TYR E 259 ? O TYR E 259 
AC4 2 3 O PHE E 260 ? O PHE E 260 N GLN E 184 ? N GLN E 184 
AC4 3 4 N SER E 179 ? N SER E 179 O THR E 303 ? O THR E 303 
AC5 1 2 N VAL F 63  ? N VAL F 63  O HIS F 106 ? O HIS F 106 
AC5 2 3 O ILE F 107 ? O ILE F 107 N ILE F 22  ? N ILE F 22  
AC5 3 4 N ALA F 21  ? N ALA F 21  O GLY F 138 ? O GLY F 138 
AC6 1 2 N LEU F 89  ? N LEU F 89  O ALA F 96  ? O ALA F 96  
AC7 1 2 N LEU F 242 ? N LEU F 242 O TYR F 263 ? O TYR F 263 
AC7 2 3 O PHE F 256 ? O PHE F 256 N HIS F 188 ? N HIS F 188 
AC7 3 4 N LEU F 187 ? N LEU F 187 O THR F 294 ? O THR F 294 
AC8 1 2 N MET F 246 ? N MET F 246 O TYR F 259 ? O TYR F 259 
AC8 2 3 O PHE F 256 ? O PHE F 256 N HIS F 188 ? N HIS F 188 
AC8 3 4 N ALA F 181 ? N ALA F 181 O PHE F 301 ? O PHE F 301 
# 
_pdbx_entry_details.entry_id                   9FB7 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OG1 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   THR 
_pdbx_validate_close_contact.auth_seq_id_1    99 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   HOH 
_pdbx_validate_close_contact.auth_seq_id_2    501 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.17 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 NE A ARG 79  ? ? CZ A ARG 79  ? ? NH2 A ARG 79  ? ? 116.49 120.30 -3.81  0.50 N 
2  1 CG A ARG 87  ? ? CD A ARG 87  ? ? NE  A ARG 87  ? ? 96.55  111.80 -15.25 2.10 N 
3  1 NE A ARG 125 ? ? CZ A ARG 125 ? ? NH1 A ARG 125 ? ? 116.86 120.30 -3.44  0.50 N 
4  1 N  A PHE 142 ? ? CA A PHE 142 ? ? CB  A PHE 142 ? ? 122.36 110.60 11.76  1.80 N 
5  1 NE A ARG 145 ? ? CZ A ARG 145 ? ? NH2 A ARG 145 ? ? 117.22 120.30 -3.08  0.50 N 
6  1 CG A MET 210 ? ? SD A MET 210 ? ? CE  A MET 210 ? ? 110.05 100.20 9.85   1.60 N 
7  1 CB A ASP 212 ? ? CG A ASP 212 ? ? OD2 A ASP 212 ? ? 112.64 118.30 -5.66  0.90 N 
8  1 CB B GLU 7   ? ? CA B GLU 7   ? ? C   B GLU 7   ? ? 122.95 110.40 12.55  2.00 N 
9  1 NE B ARG 207 ? ? CZ B ARG 207 ? ? NH1 B ARG 207 ? ? 116.41 120.30 -3.89  0.50 N 
10 1 NE B ARG 207 ? ? CZ B ARG 207 ? ? NH2 B ARG 207 ? ? 124.24 120.30 3.94   0.50 N 
11 1 CB C GLU 7   ? ? CA C GLU 7   ? ? C   C GLU 7   ? ? 124.45 110.40 14.05  2.00 N 
12 1 CG C MET 12  ? ? SD C MET 12  ? ? CE  C MET 12  ? ? 110.48 100.20 10.28  1.60 N 
13 1 NE C ARG 127 ? ? CZ C ARG 127 ? ? NH2 C ARG 127 ? ? 117.00 120.30 -3.30  0.50 N 
14 1 NE C ARG 207 ? ? CZ C ARG 207 ? ? NH1 C ARG 207 ? ? 124.91 120.30 4.61   0.50 N 
15 1 NE C ARG 207 ? ? CZ C ARG 207 ? ? NH2 C ARG 207 ? ? 116.64 120.30 -3.66  0.50 N 
16 1 CB C ASP 212 ? ? CG C ASP 212 ? ? OD2 C ASP 212 ? ? 112.78 118.30 -5.52  0.90 N 
17 1 CG D MET 12  ? ? SD D MET 12  ? ? CE  D MET 12  ? ? 111.04 100.20 10.84  1.60 N 
18 1 CG D ARG 87  ? ? CD D ARG 87  ? ? NE  D ARG 87  ? ? 96.91  111.80 -14.89 2.10 N 
19 1 N  D ARG 95  ? ? CA D ARG 95  ? ? CB  D ARG 95  ? ? 98.28  110.60 -12.32 1.80 N 
20 1 CG D ARG 95  ? ? CD D ARG 95  ? ? NE  D ARG 95  ? ? 98.52  111.80 -13.28 2.10 N 
21 1 CD D ARG 111 ? ? NE D ARG 111 ? ? CZ  D ARG 111 ? ? 132.92 123.60 9.32   1.40 N 
22 1 NE D ARG 111 ? ? CZ D ARG 111 ? ? NH1 D ARG 111 ? ? 124.31 120.30 4.01   0.50 N 
23 1 CA D ARG 164 ? ? CB D ARG 164 ? ? CG  D ARG 164 ? ? 128.36 113.40 14.96  2.20 N 
24 1 NE D ARG 207 ? ? CZ D ARG 207 ? ? NH1 D ARG 207 ? ? 124.40 120.30 4.10   0.50 N 
25 1 CB D ASP 311 ? ? CA D ASP 311 ? ? C   D ASP 311 ? ? 130.38 110.40 19.98  2.00 N 
26 1 CG E ARG 87  ? ? CD E ARG 87  ? ? NE  E ARG 87  ? ? 95.70  111.80 -16.10 2.10 N 
27 1 N  E ARG 95  ? ? CA E ARG 95  ? ? CB  E ARG 95  ? ? 98.31  110.60 -12.29 1.80 N 
28 1 CG E ARG 125 ? ? CD E ARG 125 ? ? NE  E ARG 125 ? ? 96.28  111.80 -15.52 2.10 N 
29 1 NE E ARG 125 ? ? CZ E ARG 125 ? ? NH1 E ARG 125 ? ? 117.09 120.30 -3.21  0.50 N 
30 1 NE E ARG 125 ? ? CZ E ARG 125 ? ? NH2 E ARG 125 ? ? 116.90 120.30 -3.40  0.50 N 
31 1 CA E ARG 164 ? ? CB E ARG 164 ? ? CG  E ARG 164 ? ? 128.59 113.40 15.19  2.20 N 
32 1 NE E ARG 243 ? ? CZ E ARG 243 ? ? NH2 E ARG 243 ? ? 116.27 120.30 -4.03  0.50 N 
33 1 CG F MET 12  ? ? SD F MET 12  ? ? CE  F MET 12  ? ? 116.59 100.20 16.39  1.60 N 
34 1 NE F ARG 87  ? ? CZ F ARG 87  ? ? NH2 F ARG 87  ? ? 117.03 120.30 -3.27  0.50 N 
35 1 CD F ARG 111 ? ? NE F ARG 111 ? ? CZ  F ARG 111 ? ? 136.19 123.60 12.59  1.40 N 
36 1 NE F ARG 111 ? ? CZ F ARG 111 ? ? NH1 F ARG 111 ? ? 124.47 120.30 4.17   0.50 N 
37 1 CA F THR 158 ? ? CB F THR 158 ? ? OG1 F THR 158 ? ? 93.85  109.00 -15.15 2.10 N 
38 1 NE F ARG 207 ? ? CZ F ARG 207 ? ? NH1 F ARG 207 ? ? 115.74 120.30 -4.56  0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 16  ? ? -46.53  165.15  
2  1 PHE A 142 ? ? 80.47   -117.98 
3  1 ASP A 143 ? ? -114.78 68.87   
4  1 ASP A 172 ? ? -154.76 69.21   
5  1 ASP A 244 ? ? -143.52 59.42   
6  1 PRO B 16  ? ? -43.17  162.71  
7  1 ASP B 172 ? ? -154.72 67.12   
8  1 ASP B 244 ? ? -143.92 55.78   
9  1 PHE C 142 ? ? 66.50   -123.61 
10 1 ASP C 143 ? ? -107.88 67.97   
11 1 ASP C 172 ? ? -150.09 63.86   
12 1 PRO D 16  ? ? -44.16  165.63  
13 1 ASP D 143 ? ? -118.28 50.53   
14 1 ASP D 172 ? ? -154.70 69.11   
15 1 ASP D 244 ? ? -145.01 59.00   
16 1 PRO E 16  ? ? -48.46  168.09  
17 1 ASP E 146 ? ? -107.55 -169.41 
18 1 ASP E 172 ? ? -155.46 68.06   
19 1 ASP E 244 ? ? -145.30 59.59   
20 1 SER F 76  ? ? -47.54  -71.92  
21 1 ASP F 172 ? ? -153.22 65.05   
22 1 ASP F 244 ? ? -143.92 58.12   
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 GLU B 7   ? ? PRO B 8   ? ? -117.05 
2 1 GLU C 7   ? ? PRO C 8   ? ? -117.19 
3 1 GLU D 7   ? ? PRO D 8   ? ? 140.42  
4 1 GLU E 7   ? ? PRO E 8   ? ? 142.10  
5 1 GLY F 233 ? ? PRO F 234 ? ? 148.00  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG A 87  ? ? 0.088 'SIDE CHAIN' 
2  1 ARG A 95  ? ? 0.197 'SIDE CHAIN' 
3  1 ARG A 111 ? ? 0.081 'SIDE CHAIN' 
4  1 ARG A 125 ? ? 0.093 'SIDE CHAIN' 
5  1 ARG A 163 ? ? 0.092 'SIDE CHAIN' 
6  1 ARG A 208 ? ? 0.128 'SIDE CHAIN' 
7  1 ARG A 253 ? ? 0.090 'SIDE CHAIN' 
8  1 ARG A 265 ? ? 0.086 'SIDE CHAIN' 
9  1 ARG B 59  ? ? 0.095 'SIDE CHAIN' 
10 1 ARG B 253 ? ? 0.085 'SIDE CHAIN' 
11 1 ARG C 37  ? ? 0.100 'SIDE CHAIN' 
12 1 ARG C 95  ? ? 0.120 'SIDE CHAIN' 
13 1 ARG C 127 ? ? 0.107 'SIDE CHAIN' 
14 1 ARG C 164 ? ? 0.074 'SIDE CHAIN' 
15 1 ARG D 37  ? ? 0.127 'SIDE CHAIN' 
16 1 ARG D 59  ? ? 0.131 'SIDE CHAIN' 
17 1 ARG D 87  ? ? 0.104 'SIDE CHAIN' 
18 1 ARG D 95  ? ? 0.142 'SIDE CHAIN' 
19 1 ARG D 203 ? ? 0.107 'SIDE CHAIN' 
20 1 ARG D 253 ? ? 0.084 'SIDE CHAIN' 
21 1 ARG D 276 ? ? 0.078 'SIDE CHAIN' 
22 1 ARG E 37  ? ? 0.100 'SIDE CHAIN' 
23 1 ARG E 59  ? ? 0.087 'SIDE CHAIN' 
24 1 ARG E 87  ? ? 0.116 'SIDE CHAIN' 
25 1 ARG E 95  ? ? 0.199 'SIDE CHAIN' 
26 1 ARG E 125 ? ? 0.151 'SIDE CHAIN' 
27 1 ARG E 253 ? ? 0.075 'SIDE CHAIN' 
28 1 ARG F 125 ? A 0.120 'SIDE CHAIN' 
29 1 ARG F 164 ? ? 0.082 'SIDE CHAIN' 
30 1 ARG F 203 ? ? 0.157 'SIDE CHAIN' 
31 1 ARG F 207 ? ? 0.095 'SIDE CHAIN' 
32 1 ARG F 253 ? ? 0.076 'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A GLY 2   ? A GLY 2   
3  1 Y 1 A GLY 3   ? A GLY 3   
4  1 Y 1 A GLU 4   ? A GLU 4   
5  1 Y 1 A VAL 5   ? A VAL 5   
6  1 Y 1 A GLU 6   ? A GLU 6   
7  1 Y 1 A GLU 7   ? A GLU 7   
8  1 Y 1 A SER 313 ? A SER 313 
9  1 Y 1 B MET 1   ? B MET 1   
10 1 Y 1 B GLY 2   ? B GLY 2   
11 1 Y 1 B GLY 3   ? B GLY 3   
12 1 Y 1 B GLU 4   ? B GLU 4   
13 1 Y 1 B VAL 5   ? B VAL 5   
14 1 Y 1 B GLU 6   ? B GLU 6   
15 1 Y 1 B LEU 312 ? B LEU 312 
16 1 Y 1 B SER 313 ? B SER 313 
17 1 Y 1 C MET 1   ? C MET 1   
18 1 Y 1 C GLY 2   ? C GLY 2   
19 1 Y 1 C GLY 3   ? C GLY 3   
20 1 Y 1 C GLU 4   ? C GLU 4   
21 1 Y 1 C VAL 5   ? C VAL 5   
22 1 Y 1 C GLU 6   ? C GLU 6   
23 1 Y 1 C SER 313 ? C SER 313 
24 1 Y 1 D MET 1   ? D MET 1   
25 1 Y 1 D GLY 2   ? D GLY 2   
26 1 Y 1 D GLY 3   ? D GLY 3   
27 1 Y 1 D GLU 4   ? D GLU 4   
28 1 Y 1 D VAL 5   ? D VAL 5   
29 1 Y 1 D GLU 6   ? D GLU 6   
30 1 Y 1 D SER 313 ? D SER 313 
31 1 Y 1 E MET 1   ? E MET 1   
32 1 Y 1 E GLY 2   ? E GLY 2   
33 1 Y 1 E GLY 3   ? E GLY 3   
34 1 Y 1 E GLU 4   ? E GLU 4   
35 1 Y 1 E VAL 5   ? E VAL 5   
36 1 Y 1 E GLU 6   ? E GLU 6   
37 1 Y 1 E SER 313 ? E SER 313 
38 1 Y 1 F MET 1   ? F MET 1   
39 1 Y 1 F GLY 2   ? F GLY 2   
40 1 Y 1 F GLY 3   ? F GLY 3   
41 1 Y 1 F GLU 4   ? F GLU 4   
42 1 Y 1 F VAL 5   ? F VAL 5   
43 1 Y 1 F GLU 6   ? F GLU 6   
44 1 Y 1 F GLU 7   ? F GLU 7   
45 1 Y 1 F SER 313 ? F SER 313 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HEM CHA  C  N N 137 
HEM CHB  C  N N 138 
HEM CHC  C  N N 139 
HEM CHD  C  N N 140 
HEM C1A  C  Y N 141 
HEM C2A  C  Y N 142 
HEM C3A  C  Y N 143 
HEM C4A  C  Y N 144 
HEM CMA  C  N N 145 
HEM CAA  C  N N 146 
HEM CBA  C  N N 147 
HEM CGA  C  N N 148 
HEM O1A  O  N N 149 
HEM O2A  O  N N 150 
HEM C1B  C  N N 151 
HEM C2B  C  N N 152 
HEM C3B  C  N N 153 
HEM C4B  C  N N 154 
HEM CMB  C  N N 155 
HEM CAB  C  N N 156 
HEM CBB  C  N N 157 
HEM C1C  C  Y N 158 
HEM C2C  C  Y N 159 
HEM C3C  C  Y N 160 
HEM C4C  C  Y N 161 
HEM CMC  C  N N 162 
HEM CAC  C  N N 163 
HEM CBC  C  N N 164 
HEM C1D  C  N N 165 
HEM C2D  C  N N 166 
HEM C3D  C  N N 167 
HEM C4D  C  N N 168 
HEM CMD  C  N N 169 
HEM CAD  C  N N 170 
HEM CBD  C  N N 171 
HEM CGD  C  N N 172 
HEM O1D  O  N N 173 
HEM O2D  O  N N 174 
HEM NA   N  Y N 175 
HEM NB   N  N N 176 
HEM NC   N  Y N 177 
HEM ND   N  N N 178 
HEM FE   FE N N 179 
HEM HHB  H  N N 180 
HEM HHC  H  N N 181 
HEM HHD  H  N N 182 
HEM HMA  H  N N 183 
HEM HMAA H  N N 184 
HEM HMAB H  N N 185 
HEM HAA  H  N N 186 
HEM HAAA H  N N 187 
HEM HBA  H  N N 188 
HEM HBAA H  N N 189 
HEM HMB  H  N N 190 
HEM HMBA H  N N 191 
HEM HMBB H  N N 192 
HEM HAB  H  N N 193 
HEM HBB  H  N N 194 
HEM HBBA H  N N 195 
HEM HMC  H  N N 196 
HEM HMCA H  N N 197 
HEM HMCB H  N N 198 
HEM HAC  H  N N 199 
HEM HBC  H  N N 200 
HEM HBCA H  N N 201 
HEM HMD  H  N N 202 
HEM HMDA H  N N 203 
HEM HMDB H  N N 204 
HEM HAD  H  N N 205 
HEM HADA H  N N 206 
HEM HBD  H  N N 207 
HEM HBDA H  N N 208 
HEM H2A  H  N N 209 
HEM H2D  H  N N 210 
HEM HHA  H  N N 211 
HIS N    N  N N 212 
HIS CA   C  N S 213 
HIS C    C  N N 214 
HIS O    O  N N 215 
HIS CB   C  N N 216 
HIS CG   C  Y N 217 
HIS ND1  N  Y N 218 
HIS CD2  C  Y N 219 
HIS CE1  C  Y N 220 
HIS NE2  N  Y N 221 
HIS OXT  O  N N 222 
HIS H    H  N N 223 
HIS H2   H  N N 224 
HIS HA   H  N N 225 
HIS HB2  H  N N 226 
HIS HB3  H  N N 227 
HIS HD1  H  N N 228 
HIS HD2  H  N N 229 
HIS HE1  H  N N 230 
HIS HE2  H  N N 231 
HIS HXT  H  N N 232 
HOH O    O  N N 233 
HOH H1   H  N N 234 
HOH H2   H  N N 235 
ILE N    N  N N 236 
ILE CA   C  N S 237 
ILE C    C  N N 238 
ILE O    O  N N 239 
ILE CB   C  N S 240 
ILE CG1  C  N N 241 
ILE CG2  C  N N 242 
ILE CD1  C  N N 243 
ILE OXT  O  N N 244 
ILE H    H  N N 245 
ILE H2   H  N N 246 
ILE HA   H  N N 247 
ILE HB   H  N N 248 
ILE HG12 H  N N 249 
ILE HG13 H  N N 250 
ILE HG21 H  N N 251 
ILE HG22 H  N N 252 
ILE HG23 H  N N 253 
ILE HD11 H  N N 254 
ILE HD12 H  N N 255 
ILE HD13 H  N N 256 
ILE HXT  H  N N 257 
LEU N    N  N N 258 
LEU CA   C  N S 259 
LEU C    C  N N 260 
LEU O    O  N N 261 
LEU CB   C  N N 262 
LEU CG   C  N N 263 
LEU CD1  C  N N 264 
LEU CD2  C  N N 265 
LEU OXT  O  N N 266 
LEU H    H  N N 267 
LEU H2   H  N N 268 
LEU HA   H  N N 269 
LEU HB2  H  N N 270 
LEU HB3  H  N N 271 
LEU HG   H  N N 272 
LEU HD11 H  N N 273 
LEU HD12 H  N N 274 
LEU HD13 H  N N 275 
LEU HD21 H  N N 276 
LEU HD22 H  N N 277 
LEU HD23 H  N N 278 
LEU HXT  H  N N 279 
LYS N    N  N N 280 
LYS CA   C  N S 281 
LYS C    C  N N 282 
LYS O    O  N N 283 
LYS CB   C  N N 284 
LYS CG   C  N N 285 
LYS CD   C  N N 286 
LYS CE   C  N N 287 
LYS NZ   N  N N 288 
LYS OXT  O  N N 289 
LYS H    H  N N 290 
LYS H2   H  N N 291 
LYS HA   H  N N 292 
LYS HB2  H  N N 293 
LYS HB3  H  N N 294 
LYS HG2  H  N N 295 
LYS HG3  H  N N 296 
LYS HD2  H  N N 297 
LYS HD3  H  N N 298 
LYS HE2  H  N N 299 
LYS HE3  H  N N 300 
LYS HZ1  H  N N 301 
LYS HZ2  H  N N 302 
LYS HZ3  H  N N 303 
LYS HXT  H  N N 304 
MET N    N  N N 305 
MET CA   C  N S 306 
MET C    C  N N 307 
MET O    O  N N 308 
MET CB   C  N N 309 
MET CG   C  N N 310 
MET SD   S  N N 311 
MET CE   C  N N 312 
MET OXT  O  N N 313 
MET H    H  N N 314 
MET H2   H  N N 315 
MET HA   H  N N 316 
MET HB2  H  N N 317 
MET HB3  H  N N 318 
MET HG2  H  N N 319 
MET HG3  H  N N 320 
MET HE1  H  N N 321 
MET HE2  H  N N 322 
MET HE3  H  N N 323 
MET HXT  H  N N 324 
MG  MG   MG N N 325 
PG4 O1   O  N N 326 
PG4 C1   C  N N 327 
PG4 C2   C  N N 328 
PG4 O2   O  N N 329 
PG4 C3   C  N N 330 
PG4 C4   C  N N 331 
PG4 O3   O  N N 332 
PG4 C5   C  N N 333 
PG4 C6   C  N N 334 
PG4 O4   O  N N 335 
PG4 C7   C  N N 336 
PG4 C8   C  N N 337 
PG4 O5   O  N N 338 
PG4 HO1  H  N N 339 
PG4 H11  H  N N 340 
PG4 H12  H  N N 341 
PG4 H21  H  N N 342 
PG4 H22  H  N N 343 
PG4 H31  H  N N 344 
PG4 H32  H  N N 345 
PG4 H41  H  N N 346 
PG4 H42  H  N N 347 
PG4 H51  H  N N 348 
PG4 H52  H  N N 349 
PG4 H61  H  N N 350 
PG4 H62  H  N N 351 
PG4 H71  H  N N 352 
PG4 H72  H  N N 353 
PG4 H81  H  N N 354 
PG4 H82  H  N N 355 
PG4 HO5  H  N N 356 
PHE N    N  N N 357 
PHE CA   C  N S 358 
PHE C    C  N N 359 
PHE O    O  N N 360 
PHE CB   C  N N 361 
PHE CG   C  Y N 362 
PHE CD1  C  Y N 363 
PHE CD2  C  Y N 364 
PHE CE1  C  Y N 365 
PHE CE2  C  Y N 366 
PHE CZ   C  Y N 367 
PHE OXT  O  N N 368 
PHE H    H  N N 369 
PHE H2   H  N N 370 
PHE HA   H  N N 371 
PHE HB2  H  N N 372 
PHE HB3  H  N N 373 
PHE HD1  H  N N 374 
PHE HD2  H  N N 375 
PHE HE1  H  N N 376 
PHE HE2  H  N N 377 
PHE HZ   H  N N 378 
PHE HXT  H  N N 379 
PRO N    N  N N 380 
PRO CA   C  N S 381 
PRO C    C  N N 382 
PRO O    O  N N 383 
PRO CB   C  N N 384 
PRO CG   C  N N 385 
PRO CD   C  N N 386 
PRO OXT  O  N N 387 
PRO H    H  N N 388 
PRO HA   H  N N 389 
PRO HB2  H  N N 390 
PRO HB3  H  N N 391 
PRO HG2  H  N N 392 
PRO HG3  H  N N 393 
PRO HD2  H  N N 394 
PRO HD3  H  N N 395 
PRO HXT  H  N N 396 
SER N    N  N N 397 
SER CA   C  N S 398 
SER C    C  N N 399 
SER O    O  N N 400 
SER CB   C  N N 401 
SER OG   O  N N 402 
SER OXT  O  N N 403 
SER H    H  N N 404 
SER H2   H  N N 405 
SER HA   H  N N 406 
SER HB2  H  N N 407 
SER HB3  H  N N 408 
SER HG   H  N N 409 
SER HXT  H  N N 410 
THR N    N  N N 411 
THR CA   C  N S 412 
THR C    C  N N 413 
THR O    O  N N 414 
THR CB   C  N R 415 
THR OG1  O  N N 416 
THR CG2  C  N N 417 
THR OXT  O  N N 418 
THR H    H  N N 419 
THR H2   H  N N 420 
THR HA   H  N N 421 
THR HB   H  N N 422 
THR HG1  H  N N 423 
THR HG21 H  N N 424 
THR HG22 H  N N 425 
THR HG23 H  N N 426 
THR HXT  H  N N 427 
TRP N    N  N N 428 
TRP CA   C  N S 429 
TRP C    C  N N 430 
TRP O    O  N N 431 
TRP CB   C  N N 432 
TRP CG   C  Y N 433 
TRP CD1  C  Y N 434 
TRP CD2  C  Y N 435 
TRP NE1  N  Y N 436 
TRP CE2  C  Y N 437 
TRP CE3  C  Y N 438 
TRP CZ2  C  Y N 439 
TRP CZ3  C  Y N 440 
TRP CH2  C  Y N 441 
TRP OXT  O  N N 442 
TRP H    H  N N 443 
TRP H2   H  N N 444 
TRP HA   H  N N 445 
TRP HB2  H  N N 446 
TRP HB3  H  N N 447 
TRP HD1  H  N N 448 
TRP HE1  H  N N 449 
TRP HE3  H  N N 450 
TRP HZ2  H  N N 451 
TRP HZ3  H  N N 452 
TRP HH2  H  N N 453 
TRP HXT  H  N N 454 
TYR N    N  N N 455 
TYR CA   C  N S 456 
TYR C    C  N N 457 
TYR O    O  N N 458 
TYR CB   C  N N 459 
TYR CG   C  Y N 460 
TYR CD1  C  Y N 461 
TYR CD2  C  Y N 462 
TYR CE1  C  Y N 463 
TYR CE2  C  Y N 464 
TYR CZ   C  Y N 465 
TYR OH   O  N N 466 
TYR OXT  O  N N 467 
TYR H    H  N N 468 
TYR H2   H  N N 469 
TYR HA   H  N N 470 
TYR HB2  H  N N 471 
TYR HB3  H  N N 472 
TYR HD1  H  N N 473 
TYR HD2  H  N N 474 
TYR HE1  H  N N 475 
TYR HE2  H  N N 476 
TYR HH   H  N N 477 
TYR HXT  H  N N 478 
VAL N    N  N N 479 
VAL CA   C  N S 480 
VAL C    C  N N 481 
VAL O    O  N N 482 
VAL CB   C  N N 483 
VAL CG1  C  N N 484 
VAL CG2  C  N N 485 
VAL OXT  O  N N 486 
VAL H    H  N N 487 
VAL H2   H  N N 488 
VAL HA   H  N N 489 
VAL HB   H  N N 490 
VAL HG11 H  N N 491 
VAL HG12 H  N N 492 
VAL HG13 H  N N 493 
VAL HG21 H  N N 494 
VAL HG22 H  N N 495 
VAL HG23 H  N N 496 
VAL HXT  H  N N 497 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HEM CHA C1A  sing N N 129 
HEM CHA C4D  doub N N 130 
HEM CHA HHA  sing N N 131 
HEM CHB C4A  sing N N 132 
HEM CHB C1B  doub N N 133 
HEM CHB HHB  sing N N 134 
HEM CHC C4B  sing N N 135 
HEM CHC C1C  doub N N 136 
HEM CHC HHC  sing N N 137 
HEM CHD C4C  doub N N 138 
HEM CHD C1D  sing N N 139 
HEM CHD HHD  sing N N 140 
HEM C1A C2A  doub Y N 141 
HEM C1A NA   sing Y N 142 
HEM C2A C3A  sing Y N 143 
HEM C2A CAA  sing N N 144 
HEM C3A C4A  doub Y N 145 
HEM C3A CMA  sing N N 146 
HEM C4A NA   sing Y N 147 
HEM CMA HMA  sing N N 148 
HEM CMA HMAA sing N N 149 
HEM CMA HMAB sing N N 150 
HEM CAA CBA  sing N N 151 
HEM CAA HAA  sing N N 152 
HEM CAA HAAA sing N N 153 
HEM CBA CGA  sing N N 154 
HEM CBA HBA  sing N N 155 
HEM CBA HBAA sing N N 156 
HEM CGA O1A  doub N N 157 
HEM CGA O2A  sing N N 158 
HEM C1B C2B  sing N N 159 
HEM C1B NB   sing N N 160 
HEM C2B C3B  doub N N 161 
HEM C2B CMB  sing N N 162 
HEM C3B C4B  sing N N 163 
HEM C3B CAB  sing N N 164 
HEM C4B NB   doub N N 165 
HEM CMB HMB  sing N N 166 
HEM CMB HMBA sing N N 167 
HEM CMB HMBB sing N N 168 
HEM CAB CBB  doub N N 169 
HEM CAB HAB  sing N N 170 
HEM CBB HBB  sing N N 171 
HEM CBB HBBA sing N N 172 
HEM C1C C2C  sing Y N 173 
HEM C1C NC   sing Y N 174 
HEM C2C C3C  doub Y N 175 
HEM C2C CMC  sing N N 176 
HEM C3C C4C  sing Y N 177 
HEM C3C CAC  sing N N 178 
HEM C4C NC   sing Y N 179 
HEM CMC HMC  sing N N 180 
HEM CMC HMCA sing N N 181 
HEM CMC HMCB sing N N 182 
HEM CAC CBC  doub N N 183 
HEM CAC HAC  sing N N 184 
HEM CBC HBC  sing N N 185 
HEM CBC HBCA sing N N 186 
HEM C1D C2D  sing N N 187 
HEM C1D ND   doub N N 188 
HEM C2D C3D  doub N N 189 
HEM C2D CMD  sing N N 190 
HEM C3D C4D  sing N N 191 
HEM C3D CAD  sing N N 192 
HEM C4D ND   sing N N 193 
HEM CMD HMD  sing N N 194 
HEM CMD HMDA sing N N 195 
HEM CMD HMDB sing N N 196 
HEM CAD CBD  sing N N 197 
HEM CAD HAD  sing N N 198 
HEM CAD HADA sing N N 199 
HEM CBD CGD  sing N N 200 
HEM CBD HBD  sing N N 201 
HEM CBD HBDA sing N N 202 
HEM CGD O1D  doub N N 203 
HEM CGD O2D  sing N N 204 
HEM O2A H2A  sing N N 205 
HEM O2D H2D  sing N N 206 
HEM FE  NA   sing N N 207 
HEM FE  NB   sing N N 208 
HEM FE  NC   sing N N 209 
HEM FE  ND   sing N N 210 
HIS N   CA   sing N N 211 
HIS N   H    sing N N 212 
HIS N   H2   sing N N 213 
HIS CA  C    sing N N 214 
HIS CA  CB   sing N N 215 
HIS CA  HA   sing N N 216 
HIS C   O    doub N N 217 
HIS C   OXT  sing N N 218 
HIS CB  CG   sing N N 219 
HIS CB  HB2  sing N N 220 
HIS CB  HB3  sing N N 221 
HIS CG  ND1  sing Y N 222 
HIS CG  CD2  doub Y N 223 
HIS ND1 CE1  doub Y N 224 
HIS ND1 HD1  sing N N 225 
HIS CD2 NE2  sing Y N 226 
HIS CD2 HD2  sing N N 227 
HIS CE1 NE2  sing Y N 228 
HIS CE1 HE1  sing N N 229 
HIS NE2 HE2  sing N N 230 
HIS OXT HXT  sing N N 231 
HOH O   H1   sing N N 232 
HOH O   H2   sing N N 233 
ILE N   CA   sing N N 234 
ILE N   H    sing N N 235 
ILE N   H2   sing N N 236 
ILE CA  C    sing N N 237 
ILE CA  CB   sing N N 238 
ILE CA  HA   sing N N 239 
ILE C   O    doub N N 240 
ILE C   OXT  sing N N 241 
ILE CB  CG1  sing N N 242 
ILE CB  CG2  sing N N 243 
ILE CB  HB   sing N N 244 
ILE CG1 CD1  sing N N 245 
ILE CG1 HG12 sing N N 246 
ILE CG1 HG13 sing N N 247 
ILE CG2 HG21 sing N N 248 
ILE CG2 HG22 sing N N 249 
ILE CG2 HG23 sing N N 250 
ILE CD1 HD11 sing N N 251 
ILE CD1 HD12 sing N N 252 
ILE CD1 HD13 sing N N 253 
ILE OXT HXT  sing N N 254 
LEU N   CA   sing N N 255 
LEU N   H    sing N N 256 
LEU N   H2   sing N N 257 
LEU CA  C    sing N N 258 
LEU CA  CB   sing N N 259 
LEU CA  HA   sing N N 260 
LEU C   O    doub N N 261 
LEU C   OXT  sing N N 262 
LEU CB  CG   sing N N 263 
LEU CB  HB2  sing N N 264 
LEU CB  HB3  sing N N 265 
LEU CG  CD1  sing N N 266 
LEU CG  CD2  sing N N 267 
LEU CG  HG   sing N N 268 
LEU CD1 HD11 sing N N 269 
LEU CD1 HD12 sing N N 270 
LEU CD1 HD13 sing N N 271 
LEU CD2 HD21 sing N N 272 
LEU CD2 HD22 sing N N 273 
LEU CD2 HD23 sing N N 274 
LEU OXT HXT  sing N N 275 
LYS N   CA   sing N N 276 
LYS N   H    sing N N 277 
LYS N   H2   sing N N 278 
LYS CA  C    sing N N 279 
LYS CA  CB   sing N N 280 
LYS CA  HA   sing N N 281 
LYS C   O    doub N N 282 
LYS C   OXT  sing N N 283 
LYS CB  CG   sing N N 284 
LYS CB  HB2  sing N N 285 
LYS CB  HB3  sing N N 286 
LYS CG  CD   sing N N 287 
LYS CG  HG2  sing N N 288 
LYS CG  HG3  sing N N 289 
LYS CD  CE   sing N N 290 
LYS CD  HD2  sing N N 291 
LYS CD  HD3  sing N N 292 
LYS CE  NZ   sing N N 293 
LYS CE  HE2  sing N N 294 
LYS CE  HE3  sing N N 295 
LYS NZ  HZ1  sing N N 296 
LYS NZ  HZ2  sing N N 297 
LYS NZ  HZ3  sing N N 298 
LYS OXT HXT  sing N N 299 
MET N   CA   sing N N 300 
MET N   H    sing N N 301 
MET N   H2   sing N N 302 
MET CA  C    sing N N 303 
MET CA  CB   sing N N 304 
MET CA  HA   sing N N 305 
MET C   O    doub N N 306 
MET C   OXT  sing N N 307 
MET CB  CG   sing N N 308 
MET CB  HB2  sing N N 309 
MET CB  HB3  sing N N 310 
MET CG  SD   sing N N 311 
MET CG  HG2  sing N N 312 
MET CG  HG3  sing N N 313 
MET SD  CE   sing N N 314 
MET CE  HE1  sing N N 315 
MET CE  HE2  sing N N 316 
MET CE  HE3  sing N N 317 
MET OXT HXT  sing N N 318 
PG4 O1  C1   sing N N 319 
PG4 O1  HO1  sing N N 320 
PG4 C1  C2   sing N N 321 
PG4 C1  H11  sing N N 322 
PG4 C1  H12  sing N N 323 
PG4 C2  O2   sing N N 324 
PG4 C2  H21  sing N N 325 
PG4 C2  H22  sing N N 326 
PG4 O2  C3   sing N N 327 
PG4 C3  C4   sing N N 328 
PG4 C3  H31  sing N N 329 
PG4 C3  H32  sing N N 330 
PG4 C4  O3   sing N N 331 
PG4 C4  H41  sing N N 332 
PG4 C4  H42  sing N N 333 
PG4 O3  C5   sing N N 334 
PG4 C5  C6   sing N N 335 
PG4 C5  H51  sing N N 336 
PG4 C5  H52  sing N N 337 
PG4 C6  O4   sing N N 338 
PG4 C6  H61  sing N N 339 
PG4 C6  H62  sing N N 340 
PG4 O4  C7   sing N N 341 
PG4 C7  C8   sing N N 342 
PG4 C7  H71  sing N N 343 
PG4 C7  H72  sing N N 344 
PG4 C8  O5   sing N N 345 
PG4 C8  H81  sing N N 346 
PG4 C8  H82  sing N N 347 
PG4 O5  HO5  sing N N 348 
PHE N   CA   sing N N 349 
PHE N   H    sing N N 350 
PHE N   H2   sing N N 351 
PHE CA  C    sing N N 352 
PHE CA  CB   sing N N 353 
PHE CA  HA   sing N N 354 
PHE C   O    doub N N 355 
PHE C   OXT  sing N N 356 
PHE CB  CG   sing N N 357 
PHE CB  HB2  sing N N 358 
PHE CB  HB3  sing N N 359 
PHE CG  CD1  doub Y N 360 
PHE CG  CD2  sing Y N 361 
PHE CD1 CE1  sing Y N 362 
PHE CD1 HD1  sing N N 363 
PHE CD2 CE2  doub Y N 364 
PHE CD2 HD2  sing N N 365 
PHE CE1 CZ   doub Y N 366 
PHE CE1 HE1  sing N N 367 
PHE CE2 CZ   sing Y N 368 
PHE CE2 HE2  sing N N 369 
PHE CZ  HZ   sing N N 370 
PHE OXT HXT  sing N N 371 
PRO N   CA   sing N N 372 
PRO N   CD   sing N N 373 
PRO N   H    sing N N 374 
PRO CA  C    sing N N 375 
PRO CA  CB   sing N N 376 
PRO CA  HA   sing N N 377 
PRO C   O    doub N N 378 
PRO C   OXT  sing N N 379 
PRO CB  CG   sing N N 380 
PRO CB  HB2  sing N N 381 
PRO CB  HB3  sing N N 382 
PRO CG  CD   sing N N 383 
PRO CG  HG2  sing N N 384 
PRO CG  HG3  sing N N 385 
PRO CD  HD2  sing N N 386 
PRO CD  HD3  sing N N 387 
PRO OXT HXT  sing N N 388 
SER N   CA   sing N N 389 
SER N   H    sing N N 390 
SER N   H2   sing N N 391 
SER CA  C    sing N N 392 
SER CA  CB   sing N N 393 
SER CA  HA   sing N N 394 
SER C   O    doub N N 395 
SER C   OXT  sing N N 396 
SER CB  OG   sing N N 397 
SER CB  HB2  sing N N 398 
SER CB  HB3  sing N N 399 
SER OG  HG   sing N N 400 
SER OXT HXT  sing N N 401 
THR N   CA   sing N N 402 
THR N   H    sing N N 403 
THR N   H2   sing N N 404 
THR CA  C    sing N N 405 
THR CA  CB   sing N N 406 
THR CA  HA   sing N N 407 
THR C   O    doub N N 408 
THR C   OXT  sing N N 409 
THR CB  OG1  sing N N 410 
THR CB  CG2  sing N N 411 
THR CB  HB   sing N N 412 
THR OG1 HG1  sing N N 413 
THR CG2 HG21 sing N N 414 
THR CG2 HG22 sing N N 415 
THR CG2 HG23 sing N N 416 
THR OXT HXT  sing N N 417 
TRP N   CA   sing N N 418 
TRP N   H    sing N N 419 
TRP N   H2   sing N N 420 
TRP CA  C    sing N N 421 
TRP CA  CB   sing N N 422 
TRP CA  HA   sing N N 423 
TRP C   O    doub N N 424 
TRP C   OXT  sing N N 425 
TRP CB  CG   sing N N 426 
TRP CB  HB2  sing N N 427 
TRP CB  HB3  sing N N 428 
TRP CG  CD1  doub Y N 429 
TRP CG  CD2  sing Y N 430 
TRP CD1 NE1  sing Y N 431 
TRP CD1 HD1  sing N N 432 
TRP CD2 CE2  doub Y N 433 
TRP CD2 CE3  sing Y N 434 
TRP NE1 CE2  sing Y N 435 
TRP NE1 HE1  sing N N 436 
TRP CE2 CZ2  sing Y N 437 
TRP CE3 CZ3  doub Y N 438 
TRP CE3 HE3  sing N N 439 
TRP CZ2 CH2  doub Y N 440 
TRP CZ2 HZ2  sing N N 441 
TRP CZ3 CH2  sing Y N 442 
TRP CZ3 HZ3  sing N N 443 
TRP CH2 HH2  sing N N 444 
TRP OXT HXT  sing N N 445 
TYR N   CA   sing N N 446 
TYR N   H    sing N N 447 
TYR N   H2   sing N N 448 
TYR CA  C    sing N N 449 
TYR CA  CB   sing N N 450 
TYR CA  HA   sing N N 451 
TYR C   O    doub N N 452 
TYR C   OXT  sing N N 453 
TYR CB  CG   sing N N 454 
TYR CB  HB2  sing N N 455 
TYR CB  HB3  sing N N 456 
TYR CG  CD1  doub Y N 457 
TYR CG  CD2  sing Y N 458 
TYR CD1 CE1  sing Y N 459 
TYR CD1 HD1  sing N N 460 
TYR CD2 CE2  doub Y N 461 
TYR CD2 HD2  sing N N 462 
TYR CE1 CZ   doub Y N 463 
TYR CE1 HE1  sing N N 464 
TYR CE2 CZ   sing Y N 465 
TYR CE2 HE2  sing N N 466 
TYR CZ  OH   sing N N 467 
TYR OH  HH   sing N N 468 
TYR OXT HXT  sing N N 469 
VAL N   CA   sing N N 470 
VAL N   H    sing N N 471 
VAL N   H2   sing N N 472 
VAL CA  C    sing N N 473 
VAL CA  CB   sing N N 474 
VAL CA  HA   sing N N 475 
VAL C   O    doub N N 476 
VAL C   OXT  sing N N 477 
VAL CB  CG1  sing N N 478 
VAL CB  CG2  sing N N 479 
VAL CB  HB   sing N N 480 
VAL CG1 HG11 sing N N 481 
VAL CG1 HG12 sing N N 482 
VAL CG1 HG13 sing N N 483 
VAL CG2 HG21 sing N N 484 
VAL CG2 HG22 sing N N 485 
VAL CG2 HG23 sing N N 486 
VAL OXT HXT  sing N N 487 
# 
_pdbx_audit_support.funding_organization   'Biotechnology and Biological Sciences Research Council (BBSRC)' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6YRJ 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_serial_crystallography_data_reduction.crystal_hits          21216 
_pdbx_serial_crystallography_data_reduction.diffrn_id             1 
_pdbx_serial_crystallography_data_reduction.droplet_hits          ? 
_pdbx_serial_crystallography_data_reduction.frame_hits            ? 
_pdbx_serial_crystallography_data_reduction.frames_failed_index   ? 
_pdbx_serial_crystallography_data_reduction.frames_indexed        ? 
_pdbx_serial_crystallography_data_reduction.frames_total          ? 
_pdbx_serial_crystallography_data_reduction.lattices_indexed      ? 
_pdbx_serial_crystallography_data_reduction.lattices_merged       ? 
_pdbx_serial_crystallography_data_reduction.xfel_pulse_events     ? 
_pdbx_serial_crystallography_data_reduction.xfel_run_numbers      ? 
# 
_pdbx_serial_crystallography_measurement.collection_time_total        ? 
_pdbx_serial_crystallography_measurement.collimation                  ? 
_pdbx_serial_crystallography_measurement.diffrn_id                    1 
_pdbx_serial_crystallography_measurement.focal_spot_size              ? 
_pdbx_serial_crystallography_measurement.photons_per_pulse            ? 
_pdbx_serial_crystallography_measurement.pulse_duration               ? 
_pdbx_serial_crystallography_measurement.pulse_energy                 2.05e-9 
_pdbx_serial_crystallography_measurement.pulse_photon_energy          ? 
_pdbx_serial_crystallography_measurement.source_distance              ? 
_pdbx_serial_crystallography_measurement.source_size                  64 
_pdbx_serial_crystallography_measurement.xfel_pulse_repetition_rate   ? 
# 
_pdbx_serial_crystallography_sample_delivery_fixed_target.crystals_per_unit               25600 
_pdbx_serial_crystallography_sample_delivery_fixed_target.description                     ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.details                         ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.diffrn_id                       1 
_pdbx_serial_crystallography_sample_delivery_fixed_target.motion_control                  ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_dehydration_prevention   mylar 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_holding                  'silicone chip' 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_solvent                  ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_unit_size                ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.support_base                    ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.velocity_horizontal             ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.velocity_vertical               ? 
# 
_atom_sites.entry_id                    9FB7 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.011509 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008202 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005011 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
FE 
MG 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . PRO A 1 8   ? -0.614  16.756  47.577  1.00 67.28  ? 8   PRO A N   1 
ATOM   2     C  CA  . PRO A 1 8   ? -1.125  16.546  46.211  1.00 59.20  ? 8   PRO A CA  1 
ATOM   3     C  C   . PRO A 1 8   ? -0.118  16.269  45.079  1.00 54.01  ? 8   PRO A C   1 
ATOM   4     O  O   . PRO A 1 8   ? 0.872   16.990  44.952  1.00 61.92  ? 8   PRO A O   1 
ATOM   5     C  CB  . PRO A 1 8   ? -1.926  17.858  45.989  1.00 59.97  ? 8   PRO A CB  1 
ATOM   6     C  CG  . PRO A 1 8   ? -1.167  18.906  46.796  1.00 62.11  ? 8   PRO A CG  1 
ATOM   7     C  CD  . PRO A 1 8   ? -0.371  18.166  47.873  1.00 61.04  ? 8   PRO A CD  1 
ATOM   8     N  N   . GLU A 1 9   ? -0.366  15.178  44.307  1.00 51.29  ? 9   GLU A N   1 
ATOM   9     C  CA  . GLU A 1 9   ? 0.491   14.670  43.215  1.00 49.62  ? 9   GLU A CA  1 
ATOM   10    C  C   . GLU A 1 9   ? 0.315   15.623  42.012  1.00 47.78  ? 9   GLU A C   1 
ATOM   11    O  O   . GLU A 1 9   ? -0.791  15.836  41.505  1.00 41.02  ? 9   GLU A O   1 
ATOM   12    C  CB  . GLU A 1 9   ? 0.215   13.158  42.957  1.00 49.42  ? 9   GLU A CB  1 
ATOM   13    C  CG  . GLU A 1 9   ? 0.997   12.348  41.905  1.00 44.70  ? 9   GLU A CG  1 
ATOM   14    N  N   . PRO A 1 10  ? 1.365   16.319  41.531  1.00 41.87  ? 10  PRO A N   1 
ATOM   15    C  CA  . PRO A 1 10  ? 1.278   17.097  40.282  1.00 43.14  ? 10  PRO A CA  1 
ATOM   16    C  C   . PRO A 1 10  ? 1.265   16.214  39.037  1.00 41.23  ? 10  PRO A C   1 
ATOM   17    O  O   . PRO A 1 10  ? 1.644   15.036  39.120  1.00 32.38  ? 10  PRO A O   1 
ATOM   18    C  CB  . PRO A 1 10  ? 2.534   17.976  40.293  1.00 40.84  ? 10  PRO A CB  1 
ATOM   19    C  CG  . PRO A 1 10  ? 3.520   17.133  41.046  1.00 41.80  ? 10  PRO A CG  1 
ATOM   20    C  CD  . PRO A 1 10  ? 2.679   16.446  42.161  1.00 41.46  ? 10  PRO A CD  1 
ATOM   21    N  N   . GLN A 1 11  ? 0.859   16.802  37.892  1.00 37.60  ? 11  GLN A N   1 
ATOM   22    C  CA  . GLN A 1 11  ? 1.026   16.094  36.639  1.00 32.37  ? 11  GLN A CA  1 
ATOM   23    C  C   . GLN A 1 11  ? 2.517   16.088  36.320  1.00 30.97  ? 11  GLN A C   1 
ATOM   24    O  O   . GLN A 1 11  ? 3.277   16.706  37.053  1.00 29.12  ? 11  GLN A O   1 
ATOM   25    C  CB  . GLN A 1 11  ? 0.199   16.663  35.490  1.00 30.84  ? 11  GLN A CB  1 
ATOM   26    C  CG  . GLN A 1 11  ? -1.303  16.462  35.593  1.00 27.05  ? 11  GLN A CG  1 
ATOM   27    C  CD  . GLN A 1 11  ? -1.969  17.099  34.391  1.00 28.91  ? 11  GLN A CD  1 
ATOM   28    O  OE1 . GLN A 1 11  ? -1.847  16.648  33.250  1.00 31.26  ? 11  GLN A OE1 1 
ATOM   29    N  NE2 . GLN A 1 11  ? -2.624  18.223  34.614  1.00 30.70  ? 11  GLN A NE2 1 
ATOM   30    N  N   . MET A 1 12  ? 2.897   15.401  35.224  1.00 32.40  ? 12  MET A N   1 
ATOM   31    C  CA  . MET A 1 12  ? 4.279   15.201  34.857  1.00 33.34  ? 12  MET A CA  1 
ATOM   32    C  C   . MET A 1 12  ? 4.862   16.445  34.188  1.00 33.43  ? 12  MET A C   1 
ATOM   33    O  O   . MET A 1 12  ? 5.426   16.381  33.084  1.00 34.61  ? 12  MET A O   1 
ATOM   34    C  CB  . MET A 1 12  ? 4.417   14.035  33.873  1.00 46.15  ? 12  MET A CB  1 
ATOM   35    C  CG  . MET A 1 12  ? 5.857   13.457  33.860  1.00 61.47  ? 12  MET A CG  1 
ATOM   36    S  SD  . MET A 1 12  ? 6.004   12.455  35.354  1.00 60.98  ? 12  MET A SD  1 
ATOM   37    C  CE  . MET A 1 12  ? 4.861   11.156  34.817  1.00 58.85  ? 12  MET A CE  1 
ATOM   38    N  N   . VAL A 1 13  ? 4.796   17.581  34.879  1.00 29.94  ? 13  VAL A N   1 
ATOM   39    C  CA  . VAL A 1 13  ? 5.298   18.797  34.292  1.00 28.76  ? 13  VAL A CA  1 
ATOM   40    C  C   . VAL A 1 13  ? 6.827   18.701  34.201  1.00 33.74  ? 13  VAL A C   1 
ATOM   41    O  O   . VAL A 1 13  ? 7.393   18.997  33.153  1.00 34.24  ? 13  VAL A O   1 
ATOM   42    C  CB  . VAL A 1 13  ? 4.828   20.000  35.111  1.00 27.80  ? 13  VAL A CB  1 
ATOM   43    C  CG1 . VAL A 1 13  ? 5.472   21.281  34.619  1.00 31.27  ? 13  VAL A CG1 1 
ATOM   44    C  CG2 . VAL A 1 13  ? 3.330   20.162  35.080  1.00 29.32  ? 13  VAL A CG2 1 
ATOM   45    N  N   . LEU A 1 14  ? 7.490   18.264  35.280  1.00 34.93  ? 14  LEU A N   1 
ATOM   46    C  CA  . LEU A 1 14  ? 8.925   18.006  35.269  1.00 39.66  ? 14  LEU A CA  1 
ATOM   47    C  C   . LEU A 1 14  ? 9.144   16.628  34.661  1.00 42.61  ? 14  LEU A C   1 
ATOM   48    O  O   . LEU A 1 14  ? 9.039   15.622  35.322  1.00 55.26  ? 14  LEU A O   1 
ATOM   49    C  CB  . LEU A 1 14  ? 9.535   18.080  36.667  1.00 41.47  ? 14  LEU A CB  1 
ATOM   50    C  CG  . LEU A 1 14  ? 8.979   19.207  37.542  1.00 47.41  ? 14  LEU A CG  1 
ATOM   51    C  CD1 . LEU A 1 14  ? 9.032   18.968  39.062  1.00 50.03  ? 14  LEU A CD1 1 
ATOM   52    C  CD2 . LEU A 1 14  ? 9.720   20.459  37.133  1.00 47.17  ? 14  LEU A CD2 1 
ATOM   53    N  N   . SER A 1 15  ? 9.396   16.572  33.369  1.00 46.89  ? 15  SER A N   1 
ATOM   54    C  CA  . SER A 1 15  ? 9.612   15.306  32.713  1.00 49.52  ? 15  SER A CA  1 
ATOM   55    C  C   . SER A 1 15  ? 11.115  15.192  32.475  1.00 49.45  ? 15  SER A C   1 
ATOM   56    O  O   . SER A 1 15  ? 11.795  16.201  32.357  1.00 48.03  ? 15  SER A O   1 
ATOM   57    C  CB  . SER A 1 15  ? 8.755   15.235  31.451  1.00 51.25  ? 15  SER A CB  1 
ATOM   58    O  OG  . SER A 1 15  ? 9.304   14.448  30.396  1.00 59.74  ? 15  SER A OG  1 
ATOM   59    N  N   . PRO A 1 16  ? 11.706  13.983  32.468  1.00 52.46  ? 16  PRO A N   1 
ATOM   60    C  CA  . PRO A 1 16  ? 13.008  13.793  31.832  1.00 58.93  ? 16  PRO A CA  1 
ATOM   61    C  C   . PRO A 1 16  ? 13.079  14.434  30.450  1.00 53.78  ? 16  PRO A C   1 
ATOM   62    O  O   . PRO A 1 16  ? 12.057  14.798  29.881  1.00 56.90  ? 16  PRO A O   1 
ATOM   63    C  CB  . PRO A 1 16  ? 13.163  12.264  31.752  1.00 67.93  ? 16  PRO A CB  1 
ATOM   64    C  CG  . PRO A 1 16  ? 11.809  11.685  32.174  1.00 68.39  ? 16  PRO A CG  1 
ATOM   65    C  CD  . PRO A 1 16  ? 11.171  12.745  33.066  1.00 62.36  ? 16  PRO A CD  1 
ATOM   66    N  N   . LEU A 1 17  ? 14.305  14.574  29.941  1.00 64.37  ? 17  LEU A N   1 
ATOM   67    C  CA  . LEU A 1 17  ? 14.539  14.892  28.543  1.00 61.69  ? 17  LEU A CA  1 
ATOM   68    C  C   . LEU A 1 17  ? 13.894  13.794  27.685  1.00 51.92  ? 17  LEU A C   1 
ATOM   69    O  O   . LEU A 1 17  ? 14.004  12.602  27.982  1.00 50.36  ? 17  LEU A O   1 
ATOM   70    C  CB  . LEU A 1 17  ? 16.039  15.107  28.298  1.00 64.84  ? 17  LEU A CB  1 
ATOM   71    C  CG  . LEU A 1 17  ? 16.524  16.557  28.479  1.00 66.26  ? 17  LEU A CG  1 
ATOM   72    C  CD1 . LEU A 1 17  ? 16.352  17.053  29.904  1.00 64.37  ? 17  LEU A CD1 1 
ATOM   73    C  CD2 . LEU A 1 17  ? 17.970  16.766  28.014  1.00 68.63  ? 17  LEU A CD2 1 
ATOM   74    N  N   . THR A 1 18  ? 13.102  14.245  26.701  1.00 42.67  ? 18  THR A N   1 
ATOM   75    C  CA  . THR A 1 18  ? 12.391  13.391  25.761  1.00 36.51  ? 18  THR A CA  1 
ATOM   76    C  C   . THR A 1 18  ? 12.680  13.969  24.384  1.00 35.16  ? 18  THR A C   1 
ATOM   77    O  O   . THR A 1 18  ? 12.897  15.171  24.262  1.00 33.11  ? 18  THR A O   1 
ATOM   78    C  CB  . THR A 1 18  ? 10.886  13.372  26.025  1.00 33.30  ? 18  THR A CB  1 
ATOM   79    O  OG1 . THR A 1 18  ? 10.467  14.730  26.042  1.00 34.33  ? 18  THR A OG1 1 
ATOM   80    C  CG2 . THR A 1 18  ? 10.496  12.727  27.339  1.00 34.56  ? 18  THR A CG2 1 
ATOM   81    N  N   . SER A 1 19  ? 12.671  13.131  23.348  1.00 35.52  ? 19  SER A N   1 
ATOM   82    C  CA  . SER A 1 19  ? 13.106  13.587  22.036  1.00 33.87  ? 19  SER A CA  1 
ATOM   83    C  C   . SER A 1 19  ? 11.936  13.739  21.059  1.00 28.89  ? 19  SER A C   1 
ATOM   84    O  O   . SER A 1 19  ? 12.126  14.201  19.948  1.00 26.44  ? 19  SER A O   1 
ATOM   85    C  CB  . SER A 1 19  ? 14.158  12.658  21.521  1.00 34.09  ? 19  SER A CB  1 
ATOM   86    O  OG  . SER A 1 19  ? 13.949  11.390  22.121  1.00 34.66  ? 19  SER A OG  1 
ATOM   87    N  N   . ALA A 1 20  ? 10.715  13.386  21.484  1.00 26.61  ? 20  ALA A N   1 
ATOM   88    C  CA  . ALA A 1 20  ? 9.552   13.526  20.630  1.00 24.62  ? 20  ALA A CA  1 
ATOM   89    C  C   . ALA A 1 20  ? 8.381   14.086  21.421  1.00 19.68  ? 20  ALA A C   1 
ATOM   90    O  O   . ALA A 1 20  ? 8.268   13.824  22.589  1.00 19.84  ? 20  ALA A O   1 
ATOM   91    C  CB  . ALA A 1 20  ? 9.210   12.181  20.031  1.00 23.65  ? 20  ALA A CB  1 
ATOM   92    N  N   . ALA A 1 21  ? 7.524   14.839  20.753  1.00 21.62  ? 21  ALA A N   1 
ATOM   93    C  CA  . ALA A 1 21  ? 6.363   15.444  21.377  1.00 21.44  ? 21  ALA A CA  1 
ATOM   94    C  C   . ALA A 1 21  ? 5.244   15.624  20.359  1.00 21.33  ? 21  ALA A C   1 
ATOM   95    O  O   . ALA A 1 21  ? 5.481   15.839  19.185  1.00 23.51  ? 21  ALA A O   1 
ATOM   96    C  CB  . ALA A 1 21  ? 6.741   16.773  21.981  1.00 18.92  ? 21  ALA A CB  1 
ATOM   97    N  N   . ILE A 1 22  ? 4.018   15.522  20.851  1.00 22.03  ? 22  ILE A N   1 
ATOM   98    C  CA  . ILE A 1 22  ? 2.851   16.002  20.129  1.00 22.36  ? 22  ILE A CA  1 
ATOM   99    C  C   . ILE A 1 22  ? 2.176   17.040  21.013  1.00 21.55  ? 22  ILE A C   1 
ATOM   100   O  O   . ILE A 1 22  ? 1.937   16.800  22.200  1.00 20.76  ? 22  ILE A O   1 
ATOM   101   C  CB  . ILE A 1 22  ? 1.882   14.868  19.753  1.00 23.49  ? 22  ILE A CB  1 
ATOM   102   C  CG1 . ILE A 1 22  ? 2.452   13.980  18.635  1.00 23.65  ? 22  ILE A CG1 1 
ATOM   103   C  CG2 . ILE A 1 22  ? 0.528   15.429  19.374  1.00 24.46  ? 22  ILE A CG2 1 
ATOM   104   C  CD1 . ILE A 1 22  ? 1.645   12.746  18.353  1.00 22.31  ? 22  ILE A CD1 1 
ATOM   105   N  N   . PHE A 1 23  ? 1.934   18.205  20.418  1.00 20.85  ? 23  PHE A N   1 
ATOM   106   C  CA  . PHE A 1 23  ? 1.125   19.239  21.024  1.00 22.11  ? 23  PHE A CA  1 
ATOM   107   C  C   . PHE A 1 23  ? -0.211  19.297  20.306  1.00 24.75  ? 23  PHE A C   1 
ATOM   108   O  O   . PHE A 1 23  ? -0.263  19.599  19.109  1.00 22.49  ? 23  PHE A O   1 
ATOM   109   C  CB  . PHE A 1 23  ? 1.763   20.616  20.910  1.00 21.78  ? 23  PHE A CB  1 
ATOM   110   C  CG  . PHE A 1 23  ? 3.156   20.697  21.490  1.00 23.75  ? 23  PHE A CG  1 
ATOM   111   C  CD1 . PHE A 1 23  ? 3.345   21.087  22.800  1.00 23.70  ? 23  PHE A CD1 1 
ATOM   112   C  CD2 . PHE A 1 23  ? 4.270   20.416  20.709  1.00 29.60  ? 23  PHE A CD2 1 
ATOM   113   C  CE1 . PHE A 1 23  ? 4.625   21.215  23.337  1.00 25.96  ? 23  PHE A CE1 1 
ATOM   114   C  CE2 . PHE A 1 23  ? 5.558   20.572  21.229  1.00 30.20  ? 23  PHE A CE2 1 
ATOM   115   C  CZ  . PHE A 1 23  ? 5.738   20.971  22.550  1.00 27.42  ? 23  PHE A CZ  1 
ATOM   116   N  N   . LEU A 1 24  ? -1.284  19.058  21.075  1.00 24.74  ? 24  LEU A N   1 
ATOM   117   C  CA  . LEU A 1 24  ? -2.632  19.075  20.559  1.00 24.73  ? 24  LEU A CA  1 
ATOM   118   C  C   . LEU A 1 24  ? -3.438  20.144  21.301  1.00 23.99  ? 24  LEU A C   1 
ATOM   119   O  O   . LEU A 1 24  ? -3.521  20.133  22.529  1.00 26.30  ? 24  LEU A O   1 
ATOM   120   C  CB  . LEU A 1 24  ? -3.044  17.656  20.868  1.00 25.50  ? 24  LEU A CB  1 
ATOM   121   C  CG  . LEU A 1 24  ? -4.224  17.101  20.081  1.00 33.55  ? 24  LEU A CG  1 
ATOM   122   C  CD1 . LEU A 1 24  ? -4.315  17.461  18.585  1.00 39.26  ? 24  LEU A CD1 1 
ATOM   123   C  CD2 . LEU A 1 24  ? -4.136  15.569  20.265  1.00 35.12  ? 24  LEU A CD2 1 
ATOM   124   N  N   . VAL A 1 25  ? -3.981  21.090  20.537  1.00 23.06  ? 25  VAL A N   1 
ATOM   125   C  CA  . VAL A 1 25  ? -4.851  22.117  21.065  1.00 24.24  ? 25  VAL A CA  1 
ATOM   126   C  C   . VAL A 1 25  ? -6.215  22.005  20.423  1.00 23.35  ? 25  VAL A C   1 
ATOM   127   O  O   . VAL A 1 25  ? -6.337  21.975  19.231  1.00 21.88  ? 25  VAL A O   1 
ATOM   128   C  CB  . VAL A 1 25  ? -4.293  23.524  20.856  1.00 25.39  ? 25  VAL A CB  1 
ATOM   129   C  CG1 . VAL A 1 25  ? -5.215  24.542  21.458  1.00 24.90  ? 25  VAL A CG1 1 
ATOM   130   C  CG2 . VAL A 1 25  ? -2.965  23.677  21.554  1.00 26.84  ? 25  VAL A CG2 1 
ATOM   131   N  N   . VAL A 1 26  ? -7.237  21.941  21.248  1.00 28.31  ? 26  VAL A N   1 
ATOM   132   C  CA  . VAL A 1 26  ? -8.603  21.785  20.783  1.00 27.63  ? 26  VAL A CA  1 
ATOM   133   C  C   . VAL A 1 26  ? -9.513  22.792  21.500  1.00 24.72  ? 26  VAL A C   1 
ATOM   134   O  O   . VAL A 1 26  ? -9.192  23.313  22.570  1.00 24.38  ? 26  VAL A O   1 
ATOM   135   C  CB  . VAL A 1 26  ? -9.082  20.333  20.994  1.00 26.63  ? 26  VAL A CB  1 
ATOM   136   C  CG1 . VAL A 1 26  ? -8.153  19.349  20.300  1.00 30.14  ? 26  VAL A CG1 1 
ATOM   137   C  CG2 . VAL A 1 26  ? -9.224  19.951  22.461  1.00 27.02  ? 26  VAL A CG2 1 
ATOM   138   N  N   . THR A 1 27  ? -10.671 23.051  20.877  1.00 25.86  ? 27  THR A N   1 
ATOM   139   C  CA  . THR A 1 27  ? -11.774 23.776  21.483  1.00 21.39  ? 27  THR A CA  1 
ATOM   140   C  C   . THR A 1 27  ? -12.925 22.814  21.712  1.00 21.95  ? 27  THR A C   1 
ATOM   141   O  O   . THR A 1 27  ? -13.076 21.813  20.999  1.00 21.17  ? 27  THR A O   1 
ATOM   142   C  CB  . THR A 1 27  ? -12.190 24.950  20.625  1.00 18.96  ? 27  THR A CB  1 
ATOM   143   O  OG1 . THR A 1 27  ? -12.515 24.413  19.343  1.00 20.42  ? 27  THR A OG1 1 
ATOM   144   C  CG2 . THR A 1 27  ? -11.107 26.006  20.628  1.00 18.74  ? 27  THR A CG2 1 
ATOM   145   N  N   . ILE A 1 28  ? -13.714 23.145  22.736  1.00 22.95  ? 28  ILE A N   1 
ATOM   146   C  CA  . ILE A 1 28  ? -14.816 22.302  23.140  1.00 28.45  ? 28  ILE A CA  1 
ATOM   147   C  C   . ILE A 1 28  ? -16.076 22.789  22.453  1.00 28.11  ? 28  ILE A C   1 
ATOM   148   O  O   . ILE A 1 28  ? -16.466 23.925  22.627  1.00 29.66  ? 28  ILE A O   1 
ATOM   149   C  CB  . ILE A 1 28  ? -14.981 22.310  24.670  1.00 34.22  ? 28  ILE A CB  1 
ATOM   150   C  CG1 . ILE A 1 28  ? -13.675 21.946  25.373  1.00 32.25  ? 28  ILE A CG1 1 
ATOM   151   C  CG2 . ILE A 1 28  ? -16.146 21.390  25.085  1.00 35.30  ? 28  ILE A CG2 1 
ATOM   152   C  CD1 . ILE A 1 28  ? -13.719 22.177  26.863  1.00 33.46  ? 28  ILE A CD1 1 
ATOM   153   N  N   . ASP A 1 29  ? -16.736 21.897  21.720  1.00 30.71  ? 29  ASP A N   1 
ATOM   154   C  CA  . ASP A 1 29  ? -17.968 22.249  21.034  1.00 34.32  ? 29  ASP A CA  1 
ATOM   155   C  C   . ASP A 1 29  ? -19.089 22.408  22.063  1.00 33.69  ? 29  ASP A C   1 
ATOM   156   O  O   . ASP A 1 29  ? -18.968 21.912  23.192  1.00 30.53  ? 29  ASP A O   1 
ATOM   157   C  CB  . ASP A 1 29  ? -18.296 21.175  20.012  1.00 36.77  ? 29  ASP A CB  1 
ATOM   158   C  CG  . ASP A 1 29  ? -17.292 20.967  18.882  1.00 36.95  ? 29  ASP A CG  1 
ATOM   159   O  OD1 . ASP A 1 29  ? -16.263 21.711  18.824  1.00 32.93  ? 29  ASP A OD1 1 
ATOM   160   O  OD2 . ASP A 1 29  ? -17.573 20.057  18.065  1.00 43.62  ? 29  ASP A OD2 1 
ATOM   161   N  N   . SER A 1 30  ? -20.191 23.080  21.679  1.00 35.07  ? 30  SER A N   1 
ATOM   162   C  CA  . SER A 1 30  ? -21.358 23.165  22.556  1.00 39.58  ? 30  SER A CA  1 
ATOM   163   C  C   . SER A 1 30  ? -21.847 21.757  22.834  1.00 38.23  ? 30  SER A C   1 
ATOM   164   O  O   . SER A 1 30  ? -21.999 20.972  21.893  1.00 39.19  ? 30  SER A O   1 
ATOM   165   C  CB  . SER A 1 30  ? -22.488 23.928  21.969  1.00 41.29  ? 30  SER A CB  1 
ATOM   166   O  OG  . SER A 1 30  ? -22.029 25.086  21.302  1.00 54.67  ? 30  SER A OG  1 
ATOM   167   N  N   . GLY A 1 31  ? -22.069 21.439  24.112  1.00 37.48  ? 31  GLY A N   1 
ATOM   168   C  CA  . GLY A 1 31  ? -22.597 20.124  24.445  1.00 37.21  ? 31  GLY A CA  1 
ATOM   169   C  C   . GLY A 1 31  ? -21.464 19.123  24.678  1.00 42.84  ? 31  GLY A C   1 
ATOM   170   O  O   . GLY A 1 31  ? -21.694 17.999  25.115  1.00 44.32  ? 31  GLY A O   1 
ATOM   171   N  N   . GLY A 1 32  ? -20.222 19.539  24.413  1.00 43.84  ? 32  GLY A N   1 
ATOM   172   C  CA  . GLY A 1 32  ? -19.081 18.656  24.563  1.00 48.90  ? 32  GLY A CA  1 
ATOM   173   C  C   . GLY A 1 32  ? -18.627 18.448  26.016  1.00 46.51  ? 32  GLY A C   1 
ATOM   174   O  O   . GLY A 1 32  ? -17.839 17.545  26.280  1.00 38.78  ? 32  GLY A O   1 
ATOM   175   N  N   . GLU A 1 33  ? -19.168 19.226  26.965  1.00 39.89  ? 33  GLU A N   1 
ATOM   176   C  CA  . GLU A 1 33  ? -18.559 19.353  28.282  1.00 34.46  ? 33  GLU A CA  1 
ATOM   177   C  C   . GLU A 1 33  ? -18.522 18.016  29.030  1.00 31.94  ? 33  GLU A C   1 
ATOM   178   O  O   . GLU A 1 33  ? -17.582 17.724  29.784  1.00 32.87  ? 33  GLU A O   1 
ATOM   179   C  CB  . GLU A 1 33  ? -19.287 20.434  29.071  1.00 33.83  ? 33  GLU A CB  1 
ATOM   180   C  CG  . GLU A 1 33  ? -19.083 21.860  28.544  1.00 34.18  ? 33  GLU A CG  1 
ATOM   181   C  CD  . GLU A 1 33  ? -19.985 22.305  27.396  1.00 33.43  ? 33  GLU A CD  1 
ATOM   182   O  OE1 . GLU A 1 33  ? -20.835 21.567  26.851  1.00 32.05  ? 33  GLU A OE1 1 
ATOM   183   O  OE2 . GLU A 1 33  ? -19.798 23.498  27.089  1.00 32.52  ? 33  GLU A OE2 1 
ATOM   184   N  N   . ASP A 1 34  ? -19.552 17.205  28.850  1.00 31.79  ? 34  ASP A N   1 
ATOM   185   C  CA  . ASP A 1 34  ? -19.634 15.975  29.623  1.00 37.32  ? 34  ASP A CA  1 
ATOM   186   C  C   . ASP A 1 34  ? -18.633 14.975  29.063  1.00 36.28  ? 34  ASP A C   1 
ATOM   187   O  O   . ASP A 1 34  ? -17.942 14.298  29.832  1.00 44.26  ? 34  ASP A O   1 
ATOM   188   C  CB  . ASP A 1 34  ? -21.006 15.327  29.653  1.00 43.78  ? 34  ASP A CB  1 
ATOM   189   C  CG  . ASP A 1 34  ? -22.092 16.115  30.361  1.00 50.71  ? 34  ASP A CG  1 
ATOM   190   O  OD1 . ASP A 1 34  ? -21.777 16.670  31.423  1.00 48.30  ? 34  ASP A OD1 1 
ATOM   191   O  OD2 . ASP A 1 34  ? -23.231 16.190  29.839  1.00 52.37  ? 34  ASP A OD2 1 
ATOM   192   N  N   . THR A 1 35  ? -18.549 14.871  27.733  1.00 35.57  ? 35  THR A N   1 
ATOM   193   C  CA  . THR A 1 35  ? -17.570 13.960  27.150  1.00 37.46  ? 35  THR A CA  1 
ATOM   194   C  C   . THR A 1 35  ? -16.169 14.305  27.651  1.00 33.12  ? 35  THR A C   1 
ATOM   195   O  O   . THR A 1 35  ? -15.394 13.416  28.006  1.00 27.84  ? 35  THR A O   1 
ATOM   196   C  CB  . THR A 1 35  ? -17.618 14.032  25.631  1.00 35.29  ? 35  THR A CB  1 
ATOM   197   O  OG1 . THR A 1 35  ? -18.916 13.535  25.349  1.00 36.39  ? 35  THR A OG1 1 
ATOM   198   C  CG2 . THR A 1 35  ? -16.560 13.161  24.977  1.00 35.29  ? 35  THR A CG2 1 
ATOM   199   N  N   . VAL A 1 36  ? -15.879 15.611  27.657  1.00 27.70  ? 36  VAL A N   1 
ATOM   200   C  CA  . VAL A 1 36  ? -14.600 16.121  28.100  1.00 26.58  ? 36  VAL A CA  1 
ATOM   201   C  C   . VAL A 1 36  ? -14.345 15.722  29.547  1.00 27.71  ? 36  VAL A C   1 
ATOM   202   O  O   . VAL A 1 36  ? -13.261 15.247  29.858  1.00 27.80  ? 36  VAL A O   1 
ATOM   203   C  CB  . VAL A 1 36  ? -14.470 17.646  27.914  1.00 24.32  ? 36  VAL A CB  1 
ATOM   204   C  CG1 . VAL A 1 36  ? -13.189 18.178  28.557  1.00 24.27  ? 36  VAL A CG1 1 
ATOM   205   C  CG2 . VAL A 1 36  ? -14.487 18.016  26.441  1.00 24.17  ? 36  VAL A CG2 1 
ATOM   206   N  N   . ARG A 1 37  ? -15.301 15.968  30.437  1.00 29.38  ? 37  ARG A N   1 
ATOM   207   C  CA  . ARG A 1 37  ? -15.093 15.633  31.833  1.00 31.55  ? 37  ARG A CA  1 
ATOM   208   C  C   . ARG A 1 37  ? -14.782 14.147  32.034  1.00 33.11  ? 37  ARG A C   1 
ATOM   209   O  O   . ARG A 1 37  ? -13.966 13.815  32.896  1.00 33.56  ? 37  ARG A O   1 
ATOM   210   C  CB  . ARG A 1 37  ? -16.329 15.983  32.652  1.00 37.84  ? 37  ARG A CB  1 
ATOM   211   C  CG  . ARG A 1 37  ? -16.223 17.267  33.437  1.00 45.51  ? 37  ARG A CG  1 
ATOM   212   C  CD  . ARG A 1 37  ? -17.550 17.477  34.154  1.00 49.09  ? 37  ARG A CD  1 
ATOM   213   N  NE  . ARG A 1 37  ? -18.008 18.809  33.746  1.00 53.58  ? 37  ARG A NE  1 
ATOM   214   C  CZ  . ARG A 1 37  ? -19.087 19.198  33.063  1.00 49.07  ? 37  ARG A CZ  1 
ATOM   215   N  NH1 . ARG A 1 37  ? -19.339 20.496  32.995  1.00 53.87  ? 37  ARG A NH1 1 
ATOM   216   N  NH2 . ARG A 1 37  ? -19.942 18.349  32.514  1.00 50.34  ? 37  ARG A NH2 1 
ATOM   217   N  N   . ASP A 1 38  ? -15.430 13.249  31.276  1.00 36.64  ? 38  ASP A N   1 
ATOM   218   C  CA  . ASP A 1 38  ? -15.153 11.823  31.417  1.00 39.29  ? 38  ASP A CA  1 
ATOM   219   C  C   . ASP A 1 38  ? -13.719 11.504  31.030  1.00 40.32  ? 38  ASP A C   1 
ATOM   220   O  O   . ASP A 1 38  ? -13.049 10.727  31.700  1.00 45.94  ? 38  ASP A O   1 
ATOM   221   C  CB  . ASP A 1 38  ? -15.985 10.932  30.512  1.00 45.64  ? 38  ASP A CB  1 
ATOM   222   C  CG  . ASP A 1 38  ? -17.355 10.604  31.079  1.00 57.85  ? 38  ASP A CG  1 
ATOM   223   O  OD1 . ASP A 1 38  ? -17.421 10.334  32.304  1.00 60.77  ? 38  ASP A OD1 1 
ATOM   224   O  OD2 . ASP A 1 38  ? -18.338 10.608  30.289  1.00 63.73  ? 38  ASP A OD2 1 
ATOM   225   N  N   . LEU A 1 39  ? -13.291 12.064  29.898  1.00 39.53  ? 39  LEU A N   1 
ATOM   226   C  CA  . LEU A 1 39  ? -11.941 11.857  29.404  1.00 32.87  ? 39  LEU A CA  1 
ATOM   227   C  C   . LEU A 1 39  ? -10.920 12.358  30.421  1.00 28.77  ? 39  LEU A C   1 
ATOM   228   O  O   . LEU A 1 39  ? -9.911  11.698  30.630  1.00 26.44  ? 39  LEU A O   1 
ATOM   229   C  CB  . LEU A 1 39  ? -11.823 12.568  28.057  1.00 32.46  ? 39  LEU A CB  1 
ATOM   230   C  CG  . LEU A 1 39  ? -10.534 12.427  27.256  1.00 29.71  ? 39  LEU A CG  1 
ATOM   231   C  CD1 . LEU A 1 39  ? -9.580  13.488  27.751  1.00 30.83  ? 39  LEU A CD1 1 
ATOM   232   C  CD2 . LEU A 1 39  ? -9.965  11.017  27.293  1.00 27.78  ? 39  LEU A CD2 1 
ATOM   233   N  N   . LEU A 1 40  ? -11.160 13.508  31.065  1.00 24.63  ? 40  LEU A N   1 
ATOM   234   C  CA  . LEU A 1 40  ? -10.149 14.050  31.959  1.00 26.10  ? 40  LEU A CA  1 
ATOM   235   C  C   . LEU A 1 40  ? -9.898  13.091  33.121  1.00 29.21  ? 40  LEU A C   1 
ATOM   236   O  O   . LEU A 1 40  ? -8.806  13.014  33.685  1.00 32.45  ? 40  LEU A O   1 
ATOM   237   C  CB  . LEU A 1 40  ? -10.509 15.432  32.474  1.00 29.63  ? 40  LEU A CB  1 
ATOM   238   C  CG  . LEU A 1 40  ? -10.596 16.550  31.425  1.00 31.87  ? 40  LEU A CG  1 
ATOM   239   C  CD1 . LEU A 1 40  ? -11.040 17.846  32.034  1.00 33.13  ? 40  LEU A CD1 1 
ATOM   240   C  CD2 . LEU A 1 40  ? -9.288  16.775  30.761  1.00 36.67  ? 40  LEU A CD2 1 
ATOM   241   N  N   . SER A 1 41  ? -10.924 12.358  33.521  1.00 31.92  ? 41  SER A N   1 
ATOM   242   C  CA  . SER A 1 41  ? -10.784 11.454  34.652  1.00 32.62  ? 41  SER A CA  1 
ATOM   243   C  C   . SER A 1 41  ? -10.110 10.150  34.213  1.00 32.47  ? 41  SER A C   1 
ATOM   244   O  O   . SER A 1 41  ? -9.723  9.343   35.028  1.00 30.75  ? 41  SER A O   1 
ATOM   245   C  CB  . SER A 1 41  ? -12.135 11.201  35.287  1.00 36.53  ? 41  SER A CB  1 
ATOM   246   O  OG  . SER A 1 41  ? -12.977 10.477  34.402  1.00 41.59  ? 41  SER A OG  1 
ATOM   247   N  N   . ASP A 1 42  ? -9.937  9.938   32.916  1.00 35.75  ? 42  ASP A N   1 
ATOM   248   C  CA  . ASP A 1 42  ? -9.352  8.705   32.419  1.00 34.47  ? 42  ASP A CA  1 
ATOM   249   C  C   . ASP A 1 42  ? -7.961  8.926   31.820  1.00 33.57  ? 42  ASP A C   1 
ATOM   250   O  O   . ASP A 1 42  ? -7.303  7.953   31.431  1.00 33.43  ? 42  ASP A O   1 
ATOM   251   C  CB  . ASP A 1 42  ? -10.262 8.082   31.369  1.00 36.36  ? 42  ASP A CB  1 
ATOM   252   C  CG  . ASP A 1 42  ? -11.430 7.289   31.924  1.00 41.50  ? 42  ASP A CG  1 
ATOM   253   O  OD1 . ASP A 1 42  ? -11.240 6.690   33.012  1.00 45.56  ? 42  ASP A OD1 1 
ATOM   254   O  OD2 . ASP A 1 42  ? -12.489 7.268   31.256  1.00 46.22  ? 42  ASP A OD2 1 
ATOM   255   N  N   . VAL A 1 43  ? -7.523  10.186  31.685  1.00 29.45  ? 43  VAL A N   1 
ATOM   256   C  CA  . VAL A 1 43  ? -6.359  10.443  30.871  1.00 28.66  ? 43  VAL A CA  1 
ATOM   257   C  C   . VAL A 1 43  ? -5.114  9.788   31.507  1.00 30.49  ? 43  VAL A C   1 
ATOM   258   O  O   . VAL A 1 43  ? -4.286  9.215   30.797  1.00 31.72  ? 43  VAL A O   1 
ATOM   259   C  CB  . VAL A 1 43  ? -6.210  11.937  30.589  1.00 29.04  ? 43  VAL A CB  1 
ATOM   260   C  CG1 . VAL A 1 43  ? -5.797  12.658  31.827  1.00 34.72  ? 43  VAL A CG1 1 
ATOM   261   C  CG2 . VAL A 1 43  ? -5.171  12.217  29.527  1.00 33.61  ? 43  VAL A CG2 1 
ATOM   262   N  N   . ALA A 1 44  ? -5.019  9.773   32.851  1.00 30.88  ? 44  ALA A N   1 
ATOM   263   C  CA  . ALA A 1 44  ? -3.908  9.108   33.519  1.00 26.53  ? 44  ALA A CA  1 
ATOM   264   C  C   . ALA A 1 44  ? -3.863  7.615   33.216  1.00 27.28  ? 44  ALA A C   1 
ATOM   265   O  O   . ALA A 1 44  ? -2.769  7.073   33.047  1.00 25.77  ? 44  ALA A O   1 
ATOM   266   C  CB  . ALA A 1 44  ? -3.992  9.339   34.980  1.00 26.39  ? 44  ALA A CB  1 
ATOM   267   N  N   . SER A 1 45  ? -5.031  6.952   33.114  1.00 27.82  ? 45  SER A N   1 
ATOM   268   C  CA  . SER A 1 45  ? -4.990  5.507   32.922  1.00 33.59  ? 45  SER A CA  1 
ATOM   269   C  C   . SER A 1 45  ? -4.702  5.154   31.464  1.00 31.92  ? 45  SER A C   1 
ATOM   270   O  O   . SER A 1 45  ? -4.075  4.105   31.208  1.00 33.83  ? 45  SER A O   1 
ATOM   271   C  CB  . SER A 1 45  ? -6.176  4.764   33.457  1.00 34.27  ? 45  SER A CB  1 
ATOM   272   O  OG  . SER A 1 45  ? -7.342  5.385   32.974  1.00 39.44  ? 45  SER A OG  1 
ATOM   273   N  N   . LEU A 1 46  ? -5.080  6.047   30.529  1.00 28.27  ? 46  LEU A N   1 
ATOM   274   C  CA  . LEU A 1 46  ? -4.663  5.876   29.150  1.00 27.81  ? 46  LEU A CA  1 
ATOM   275   C  C   . LEU A 1 46  ? -3.140  6.021   29.018  1.00 28.04  ? 46  LEU A C   1 
ATOM   276   O  O   . LEU A 1 46  ? -2.503  5.267   28.272  1.00 26.14  ? 46  LEU A O   1 
ATOM   277   C  CB  . LEU A 1 46  ? -5.428  6.873   28.293  1.00 27.55  ? 46  LEU A CB  1 
ATOM   278   C  CG  . LEU A 1 46  ? -6.914  6.604   28.153  1.00 26.70  ? 46  LEU A CG  1 
ATOM   279   C  CD1 . LEU A 1 46  ? -7.590  7.766   27.441  1.00 29.59  ? 46  LEU A CD1 1 
ATOM   280   C  CD2 . LEU A 1 46  ? -7.100  5.302   27.415  1.00 26.08  ? 46  LEU A CD2 1 
ATOM   281   N  N   . GLU A 1 47  ? -2.565  6.980   29.760  1.00 28.12  ? 47  GLU A N   1 
ATOM   282   C  CA  . GLU A 1 47  ? -1.133  7.168   29.770  1.00 27.93  ? 47  GLU A CA  1 
ATOM   283   C  C   . GLU A 1 47  ? -0.481  5.852   30.187  1.00 29.87  ? 47  GLU A C   1 
ATOM   284   O  O   . GLU A 1 47  ? 0.403   5.376   29.489  1.00 27.82  ? 47  GLU A O   1 
ATOM   285   C  CB  . GLU A 1 47  ? -0.856  8.385   30.652  1.00 32.22  ? 47  GLU A CB  1 
ATOM   286   C  CG  . GLU A 1 47  ? 0.621   8.673   30.883  1.00 34.73  ? 47  GLU A CG  1 
ATOM   287   C  CD  . GLU A 1 47  ? 0.944   9.772   31.877  1.00 35.07  ? 47  GLU A CD  1 
ATOM   288   O  OE1 . GLU A 1 47  ? 0.756   10.897  31.510  1.00 37.67  ? 47  GLU A OE1 1 
ATOM   289   O  OE2 . GLU A 1 47  ? 1.389   9.576   33.017  1.00 50.63  ? 47  GLU A OE2 1 
ATOM   290   N  N   . ARG A 1 48  ? -0.953  5.198   31.257  1.00 30.09  ? 48  ARG A N   1 
ATOM   291   C  CA  . ARG A 1 48  ? -0.361  3.928   31.681  1.00 29.94  ? 48  ARG A CA  1 
ATOM   292   C  C   . ARG A 1 48  ? -0.572  2.809   30.670  1.00 28.14  ? 48  ARG A C   1 
ATOM   293   O  O   . ARG A 1 48  ? 0.356   2.067   30.402  1.00 29.95  ? 48  ARG A O   1 
ATOM   294   C  CB  . ARG A 1 48  ? -0.897  3.405   33.008  1.00 32.77  ? 48  ARG A CB  1 
ATOM   295   C  CG  . ARG A 1 48  ? -0.436  4.386   34.072  1.00 42.94  ? 48  ARG A CG  1 
ATOM   296   C  CD  . ARG A 1 48  ? -0.535  3.788   35.456  1.00 49.99  ? 48  ARG A CD  1 
ATOM   297   N  NE  . ARG A 1 48  ? -1.921  3.385   35.730  1.00 52.30  ? 48  ARG A NE  1 
ATOM   298   C  CZ  . ARG A 1 48  ? -2.926  4.217   36.053  1.00 49.60  ? 48  ARG A CZ  1 
ATOM   299   N  NH1 . ARG A 1 48  ? -2.716  5.510   36.232  1.00 43.82  ? 48  ARG A NH1 1 
ATOM   300   N  NH2 . ARG A 1 48  ? -4.149  3.734   36.162  1.00 56.58  ? 48  ARG A NH2 1 
ATOM   301   N  N   . ALA A 1 49  ? -1.780  2.680   30.101  1.00 26.56  ? 49  ALA A N   1 
ATOM   302   C  CA  . ALA A 1 49  ? -2.044  1.565   29.217  1.00 26.08  ? 49  ALA A CA  1 
ATOM   303   C  C   . ALA A 1 49  ? -1.088  1.580   28.031  1.00 29.84  ? 49  ALA A C   1 
ATOM   304   O  O   . ALA A 1 49  ? -0.523  0.530   27.668  1.00 33.82  ? 49  ALA A O   1 
ATOM   305   C  CB  . ALA A 1 49  ? -3.440  1.634   28.742  1.00 27.97  ? 49  ALA A CB  1 
ATOM   306   N  N   . VAL A 1 50  ? -0.935  2.779   27.433  1.00 28.22  ? 50  VAL A N   1 
ATOM   307   C  CA  . VAL A 1 50  ? -0.128  2.944   26.236  1.00 26.73  ? 50  VAL A CA  1 
ATOM   308   C  C   . VAL A 1 50  ? 1.354   2.852   26.587  1.00 28.12  ? 50  VAL A C   1 
ATOM   309   O  O   . VAL A 1 50  ? 2.150   2.243   25.856  1.00 31.53  ? 50  VAL A O   1 
ATOM   310   C  CB  . VAL A 1 50  ? -0.405  4.280   25.534  1.00 27.04  ? 50  VAL A CB  1 
ATOM   311   C  CG1 . VAL A 1 50  ? 0.546   4.527   24.371  1.00 27.50  ? 50  VAL A CG1 1 
ATOM   312   C  CG2 . VAL A 1 50  ? -1.845  4.412   25.034  1.00 29.47  ? 50  VAL A CG2 1 
ATOM   313   N  N   . GLY A 1 51  ? 1.730   3.409   27.737  1.00 29.83  ? 51  GLY A N   1 
ATOM   314   C  CA  . GLY A 1 51  ? 3.144   3.589   28.031  1.00 33.11  ? 51  GLY A CA  1 
ATOM   315   C  C   . GLY A 1 51  ? 3.797   2.411   28.747  1.00 33.93  ? 51  GLY A C   1 
ATOM   316   O  O   . GLY A 1 51  ? 4.978   2.171   28.558  1.00 37.63  ? 51  GLY A O   1 
ATOM   317   N  N   . PHE A 1 52  ? 3.054   1.719   29.611  1.00 36.75  ? 52  PHE A N   1 
ATOM   318   C  CA  . PHE A 1 52  ? 3.650   0.742   30.502  1.00 40.03  ? 52  PHE A CA  1 
ATOM   319   C  C   . PHE A 1 52  ? 4.416   -0.322  29.719  1.00 40.21  ? 52  PHE A C   1 
ATOM   320   O  O   . PHE A 1 52  ? 5.509   -0.685  30.146  1.00 36.94  ? 52  PHE A O   1 
ATOM   321   C  CB  . PHE A 1 52  ? 2.617   0.046   31.390  1.00 39.94  ? 52  PHE A CB  1 
ATOM   322   C  CG  . PHE A 1 52  ? 3.311   -1.013  32.223  1.00 34.29  ? 52  PHE A CG  1 
ATOM   323   C  CD1 . PHE A 1 52  ? 4.040   -0.639  33.340  1.00 37.08  ? 52  PHE A CD1 1 
ATOM   324   C  CD2 . PHE A 1 52  ? 3.300   -2.350  31.839  1.00 31.45  ? 52  PHE A CD2 1 
ATOM   325   C  CE1 . PHE A 1 52  ? 4.733   -1.588  34.061  1.00 37.00  ? 52  PHE A CE1 1 
ATOM   326   C  CE2 . PHE A 1 52  ? 3.929   -3.311  32.594  1.00 33.43  ? 52  PHE A CE2 1 
ATOM   327   C  CZ  . PHE A 1 52  ? 4.648   -2.925  33.705  1.00 38.91  ? 52  PHE A CZ  1 
ATOM   328   N  N   . ARG A 1 53  ? 3.878   -0.797  28.584  1.00 42.21  ? 53  ARG A N   1 
ATOM   329   C  CA  . ARG A 1 53  ? 4.522   -1.878  27.858  1.00 44.70  ? 53  ARG A CA  1 
ATOM   330   C  C   . ARG A 1 53  ? 5.858   -1.455  27.225  1.00 46.30  ? 53  ARG A C   1 
ATOM   331   O  O   . ARG A 1 53  ? 6.604   -2.312  26.768  1.00 52.49  ? 53  ARG A O   1 
ATOM   332   C  CB  . ARG A 1 53  ? 3.531   -2.462  26.846  1.00 49.94  ? 53  ARG A CB  1 
ATOM   333   C  CG  . ARG A 1 53  ? 3.315   -1.742  25.520  1.00 58.07  ? 53  ARG A CG  1 
ATOM   334   C  CD  . ARG A 1 53  ? 2.662   -2.696  24.480  1.00 60.81  ? 53  ARG A CD  1 
ATOM   335   N  NE  . ARG A 1 53  ? 1.663   -2.010  23.651  1.00 59.84  ? 53  ARG A NE  1 
ATOM   336   C  CZ  . ARG A 1 53  ? 0.703   -1.307  24.224  1.00 65.97  ? 53  ARG A CZ  1 
ATOM   337   N  NH1 . ARG A 1 53  ? 0.645   -1.152  25.543  1.00 78.60  ? 53  ARG A NH1 1 
ATOM   338   N  NH2 . ARG A 1 53  ? -0.221  -0.762  23.482  1.00 62.04  ? 53  ARG A NH2 1 
ATOM   339   N  N   . ALA A 1 54  ? 6.160   -0.146  27.169  1.00 49.98  ? 54  ALA A N   1 
ATOM   340   C  CA  . ALA A 1 54  ? 7.425   0.353   26.638  1.00 46.05  ? 54  ALA A CA  1 
ATOM   341   C  C   . ALA A 1 54  ? 8.359   0.834   27.745  1.00 53.25  ? 54  ALA A C   1 
ATOM   342   O  O   . ALA A 1 54  ? 9.282   1.550   27.434  1.00 56.46  ? 54  ALA A O   1 
ATOM   343   C  CB  . ALA A 1 54  ? 7.155   1.480   25.661  1.00 45.71  ? 54  ALA A CB  1 
ATOM   344   N  N   . GLN A 1 55  ? 8.130   0.471   29.015  1.00 68.53  ? 55  GLN A N   1 
ATOM   345   C  CA  . GLN A 1 55  ? 8.973   0.917   30.131  1.00 77.17  ? 55  GLN A CA  1 
ATOM   346   C  C   . GLN A 1 55  ? 10.319  0.205   30.056  1.00 78.91  ? 55  GLN A C   1 
ATOM   347   O  O   . GLN A 1 55  ? 10.385  -0.881  29.491  1.00 72.04  ? 55  GLN A O   1 
ATOM   348   C  CB  . GLN A 1 55  ? 8.446   0.682   31.557  1.00 78.48  ? 55  GLN A CB  1 
ATOM   349   C  CG  . GLN A 1 55  ? 7.345   1.627   32.034  1.00 79.71  ? 55  GLN A CG  1 
ATOM   350   C  CD  . GLN A 1 55  ? 7.486   3.072   31.594  1.00 88.26  ? 55  GLN A CD  1 
ATOM   351   O  OE1 . GLN A 1 55  ? 8.423   3.490   30.908  1.00 84.14  ? 55  GLN A OE1 1 
ATOM   352   N  NE2 . GLN A 1 55  ? 6.479   3.855   31.932  1.00 97.31  ? 55  GLN A NE2 1 
ATOM   353   N  N   . PRO A 1 56  ? 11.421  0.809   30.580  1.00 84.69  ? 56  PRO A N   1 
ATOM   354   C  CA  . PRO A 1 56  ? 11.420  2.193   31.064  1.00 84.36  ? 56  PRO A CA  1 
ATOM   355   C  C   . PRO A 1 56  ? 12.000  3.247   30.096  1.00 69.23  ? 56  PRO A C   1 
ATOM   356   O  O   . PRO A 1 56  ? 12.012  4.440   30.376  1.00 71.47  ? 56  PRO A O   1 
ATOM   357   C  CB  . PRO A 1 56  ? 12.250  2.016   32.361  1.00 71.85  ? 56  PRO A CB  1 
ATOM   358   C  CG  . PRO A 1 56  ? 13.127  0.777   32.138  1.00 68.05  ? 56  PRO A CG  1 
ATOM   359   C  CD  . PRO A 1 56  ? 12.730  0.175   30.802  1.00 72.90  ? 56  PRO A CD  1 
ATOM   360   N  N   . ASP A 1 57  ? 12.419  2.831   28.909  1.00 55.15  ? 57  ASP A N   1 
ATOM   361   C  CA  . ASP A 1 57  ? 12.877  3.761   27.890  1.00 67.91  ? 57  ASP A CA  1 
ATOM   362   C  C   . ASP A 1 57  ? 11.764  4.625   27.304  1.00 62.02  ? 57  ASP A C   1 
ATOM   363   O  O   . ASP A 1 57  ? 12.060  5.595   26.632  1.00 56.78  ? 57  ASP A O   1 
ATOM   364   C  CB  . ASP A 1 57  ? 13.475  3.014   26.717  1.00 81.43  ? 57  ASP A CB  1 
ATOM   365   C  CG  . ASP A 1 57  ? 14.226  1.782   27.175  1.00 87.29  ? 57  ASP A CG  1 
ATOM   366   O  OD1 . ASP A 1 57  ? 15.034  1.921   28.137  1.00 83.74  ? 57  ASP A OD1 1 
ATOM   367   O  OD2 . ASP A 1 57  ? 13.931  0.709   26.615  1.00 92.50  ? 57  ASP A OD2 1 
ATOM   368   N  N   . GLY A 1 58  ? 10.486  4.259   27.482  1.00 50.25  ? 58  GLY A N   1 
ATOM   369   C  CA  . GLY A 1 58  ? 9.375   4.946   26.828  1.00 41.81  ? 58  GLY A CA  1 
ATOM   370   C  C   . GLY A 1 58  ? 9.250   6.412   27.264  1.00 34.25  ? 58  GLY A C   1 
ATOM   371   O  O   . GLY A 1 58  ? 9.127   7.306   26.430  1.00 29.80  ? 58  GLY A O   1 
ATOM   372   N  N   . ARG A 1 59  ? 9.227   6.648   28.581  1.00 31.69  ? 59  ARG A N   1 
ATOM   373   C  CA  . ARG A 1 59  ? 9.124   7.974   29.135  1.00 34.48  ? 59  ARG A CA  1 
ATOM   374   C  C   . ARG A 1 59  ? 7.928   8.749   28.566  1.00 31.37  ? 59  ARG A C   1 
ATOM   375   O  O   . ARG A 1 59  ? 8.001   9.967   28.398  1.00 35.90  ? 59  ARG A O   1 
ATOM   376   C  CB  . ARG A 1 59  ? 10.424  8.710   28.819  1.00 38.90  ? 59  ARG A CB  1 
ATOM   377   C  CG  . ARG A 1 59  ? 11.691  8.252   29.497  1.00 44.08  ? 59  ARG A CG  1 
ATOM   378   C  CD  . ARG A 1 59  ? 12.684  9.400   29.177  1.00 47.30  ? 59  ARG A CD  1 
ATOM   379   N  NE  . ARG A 1 59  ? 14.064  8.913   29.170  1.00 56.03  ? 59  ARG A NE  1 
ATOM   380   N  N   . LEU A 1 60  ? 6.806   8.062   28.319  1.00 26.60  ? 60  LEU A N   1 
ATOM   381   C  CA  . LEU A 1 60  ? 5.577   8.676   27.844  1.00 26.08  ? 60  LEU A CA  1 
ATOM   382   C  C   . LEU A 1 60  ? 4.914   9.435   28.982  1.00 28.52  ? 60  LEU A C   1 
ATOM   383   O  O   . LEU A 1 60  ? 4.779   8.895   30.070  1.00 31.95  ? 60  LEU A O   1 
ATOM   384   C  CB  . LEU A 1 60  ? 4.609   7.600   27.376  1.00 28.55  ? 60  LEU A CB  1 
ATOM   385   C  CG  . LEU A 1 60  ? 3.249   8.106   26.881  1.00 30.75  ? 60  LEU A CG  1 
ATOM   386   C  CD1 . LEU A 1 60  ? 3.358   8.974   25.586  1.00 31.01  ? 60  LEU A CD1 1 
ATOM   387   C  CD2 . LEU A 1 60  ? 2.389   6.891   26.601  1.00 29.72  ? 60  LEU A CD2 1 
ATOM   388   N  N   . SER A 1 61  ? 4.523   10.685  28.735  1.00 27.30  ? 61  SER A N   1 
ATOM   389   C  CA  . SER A 1 61  ? 3.847   11.504  29.723  1.00 28.78  ? 61  SER A CA  1 
ATOM   390   C  C   . SER A 1 61  ? 2.870   12.351  28.932  1.00 29.43  ? 61  SER A C   1 
ATOM   391   O  O   . SER A 1 61  ? 3.131   12.695  27.778  1.00 29.90  ? 61  SER A O   1 
ATOM   392   C  CB  . SER A 1 61  ? 4.806   12.390  30.501  1.00 30.32  ? 61  SER A CB  1 
ATOM   393   O  OG  . SER A 1 61  ? 5.030   13.631  29.836  1.00 40.15  ? 61  SER A OG  1 
ATOM   394   N  N   . CYS A 1 62  ? 1.729   12.671  29.536  1.00 27.10  ? 62  CYS A N   1 
ATOM   395   C  CA  . CYS A 1 62  ? 0.801   13.595  28.907  1.00 23.51  ? 62  CYS A CA  1 
ATOM   396   C  C   . CYS A 1 62  ? 0.488   14.649  29.941  1.00 22.81  ? 62  CYS A C   1 
ATOM   397   O  O   . CYS A 1 62  ? 0.140   14.310  31.059  1.00 24.99  ? 62  CYS A O   1 
ATOM   398   C  CB  . CYS A 1 62  ? -0.474  12.896  28.456  1.00 25.10  ? 62  CYS A CB  1 
ATOM   399   S  SG  . CYS A 1 62  ? -1.789  14.016  27.900  1.00 25.54  ? 62  CYS A SG  1 
ATOM   400   N  N   . VAL A 1 63  ? 0.645   15.916  29.620  1.00 20.89  ? 63  VAL A N   1 
ATOM   401   C  CA  . VAL A 1 63  ? 0.136   16.918  30.530  1.00 20.50  ? 63  VAL A CA  1 
ATOM   402   C  C   . VAL A 1 63  ? -1.081  17.582  29.907  1.00 22.46  ? 63  VAL A C   1 
ATOM   403   O  O   . VAL A 1 63  ? -1.034  18.003  28.761  1.00 23.10  ? 63  VAL A O   1 
ATOM   404   C  CB  . VAL A 1 63  ? 1.231   17.921  30.869  1.00 20.51  ? 63  VAL A CB  1 
ATOM   405   C  CG1 . VAL A 1 63  ? 0.716   19.054  31.726  1.00 22.12  ? 63  VAL A CG1 1 
ATOM   406   C  CG2 . VAL A 1 63  ? 2.348   17.214  31.603  1.00 23.32  ? 63  VAL A CG2 1 
ATOM   407   N  N   . THR A 1 64  ? -2.145  17.667  30.711  1.00 22.78  ? 64  THR A N   1 
ATOM   408   C  CA  . THR A 1 64  ? -3.416  18.192  30.274  1.00 24.86  ? 64  THR A CA  1 
ATOM   409   C  C   . THR A 1 64  ? -3.622  19.571  30.908  1.00 22.94  ? 64  THR A C   1 
ATOM   410   O  O   . THR A 1 64  ? -3.483  19.745  32.099  1.00 20.98  ? 64  THR A O   1 
ATOM   411   C  CB  . THR A 1 64  ? -4.528  17.241  30.705  1.00 25.85  ? 64  THR A CB  1 
ATOM   412   O  OG1 . THR A 1 64  ? -4.231  15.987  30.120  1.00 26.35  ? 64  THR A OG1 1 
ATOM   413   C  CG2 . THR A 1 64  ? -5.871  17.670  30.157  1.00 24.95  ? 64  THR A CG2 1 
ATOM   414   N  N   . GLY A 1 65  ? -3.976  20.526  30.079  1.00 22.26  ? 65  GLY A N   1 
ATOM   415   C  CA  . GLY A 1 65  ? -4.229  21.870  30.527  1.00 23.57  ? 65  GLY A CA  1 
ATOM   416   C  C   . GLY A 1 65  ? -5.585  22.357  30.012  1.00 22.98  ? 65  GLY A C   1 
ATOM   417   O  O   . GLY A 1 65  ? -6.086  21.945  28.964  1.00 18.76  ? 65  GLY A O   1 
ATOM   418   N  N   . ILE A 1 66  ? -6.135  23.310  30.775  1.00 25.23  ? 66  ILE A N   1 
ATOM   419   C  CA  . ILE A 1 66  ? -7.471  23.821  30.568  1.00 24.99  ? 66  ILE A CA  1 
ATOM   420   C  C   . ILE A 1 66  ? -7.406  25.336  30.508  1.00 23.63  ? 66  ILE A C   1 
ATOM   421   O  O   . ILE A 1 66  ? -6.762  25.955  31.354  1.00 26.55  ? 66  ILE A O   1 
ATOM   422   C  CB  . ILE A 1 66  ? -8.389  23.317  31.694  1.00 26.51  ? 66  ILE A CB  1 
ATOM   423   C  CG1 . ILE A 1 66  ? -8.418  21.800  31.725  1.00 28.43  ? 66  ILE A CG1 1 
ATOM   424   C  CG2 . ILE A 1 66  ? -9.799  23.855  31.517  1.00 26.19  ? 66  ILE A CG2 1 
ATOM   425   C  CD1 . ILE A 1 66  ? -8.752  21.270  33.088  1.00 30.88  ? 66  ILE A CD1 1 
ATOM   426   N  N   . GLY A 1 67  ? -8.085  25.903  29.509  1.00 22.28  ? 67  GLY A N   1 
ATOM   427   C  CA  . GLY A 1 67  ? -8.077  27.335  29.308  1.00 24.73  ? 67  GLY A CA  1 
ATOM   428   C  C   . GLY A 1 67  ? -9.079  28.027  30.217  1.00 26.83  ? 67  GLY A C   1 
ATOM   429   O  O   . GLY A 1 67  ? -9.880  27.388  30.904  1.00 25.91  ? 67  GLY A O   1 
ATOM   430   N  N   . SER A 1 68  ? -9.025  29.361  30.166  1.00 28.25  ? 68  SER A N   1 
ATOM   431   C  CA  . SER A 1 68  ? -9.803  30.195  31.055  1.00 29.34  ? 68  SER A CA  1 
ATOM   432   C  C   . SER A 1 68  ? -11.296 30.025  30.820  1.00 27.97  ? 68  SER A C   1 
ATOM   433   O  O   . SER A 1 68  ? -12.019 29.694  31.760  1.00 27.65  ? 68  SER A O   1 
ATOM   434   C  CB  . SER A 1 68  ? -9.417  31.618  30.879  1.00 33.66  ? 68  SER A CB  1 
ATOM   435   O  OG  . SER A 1 68  ? -9.941  32.413  31.930  1.00 30.92  ? 68  SER A OG  1 
ATOM   436   N  N   . GLU A 1 69  ? -11.753 30.245  29.583  1.00 25.71  ? 69  GLU A N   1 
ATOM   437   C  CA  . GLU A 1 69  ? -13.172 30.168  29.304  1.00 28.75  ? 69  GLU A CA  1 
ATOM   438   C  C   . GLU A 1 69  ? -13.707 28.745  29.442  1.00 34.52  ? 69  GLU A C   1 
ATOM   439   O  O   . GLU A 1 69  ? -14.855 28.565  29.825  1.00 32.55  ? 69  GLU A O   1 
ATOM   440   C  CB  . GLU A 1 69  ? -13.446 30.699  27.919  1.00 31.86  ? 69  GLU A CB  1 
ATOM   441   C  CG  . GLU A 1 69  ? -12.821 32.071  27.735  1.00 38.87  ? 69  GLU A CG  1 
ATOM   442   C  CD  . GLU A 1 69  ? -13.104 32.533  26.317  1.00 57.50  ? 69  GLU A CD  1 
ATOM   443   O  OE1 . GLU A 1 69  ? -12.409 33.500  25.926  1.00 67.97  ? 69  GLU A OE1 1 
ATOM   444   O  OE2 . GLU A 1 69  ? -13.968 31.915  25.599  1.00 62.85  ? 69  GLU A OE2 1 
ATOM   445   N  N   . ALA A 1 70  ? -12.892 27.747  29.090  1.00 34.42  ? 70  ALA A N   1 
ATOM   446   C  CA  . ALA A 1 70  ? -13.265 26.352  29.245  1.00 30.24  ? 70  ALA A CA  1 
ATOM   447   C  C   . ALA A 1 70  ? -13.386 25.995  30.722  1.00 27.36  ? 70  ALA A C   1 
ATOM   448   O  O   . ALA A 1 70  ? -14.242 25.215  31.124  1.00 24.81  ? 70  ALA A O   1 
ATOM   449   C  CB  . ALA A 1 70  ? -12.245 25.483  28.531  1.00 28.23  ? 70  ALA A CB  1 
ATOM   450   N  N   . TRP A 1 71  ? -12.525 26.577  31.546  1.00 26.49  ? 71  TRP A N   1 
ATOM   451   C  CA  . TRP A 1 71  ? -12.564 26.249  32.959  1.00 28.23  ? 71  TRP A CA  1 
ATOM   452   C  C   . TRP A 1 71  ? -13.961 26.530  33.530  1.00 30.66  ? 71  TRP A C   1 
ATOM   453   O  O   . TRP A 1 71  ? -14.506 25.746  34.299  1.00 26.45  ? 71  TRP A O   1 
ATOM   454   C  CB  . TRP A 1 71  ? -11.490 27.050  33.695  1.00 26.25  ? 71  TRP A CB  1 
ATOM   455   C  CG  . TRP A 1 71  ? -11.505 26.693  35.144  1.00 27.11  ? 71  TRP A CG  1 
ATOM   456   C  CD1 . TRP A 1 71  ? -12.376 27.127  36.092  1.00 27.61  ? 71  TRP A CD1 1 
ATOM   457   C  CD2 . TRP A 1 71  ? -10.668 25.714  35.762  1.00 29.84  ? 71  TRP A CD2 1 
ATOM   458   N  NE1 . TRP A 1 71  ? -12.118 26.492  37.267  1.00 30.50  ? 71  TRP A NE1 1 
ATOM   459   C  CE2 . TRP A 1 71  ? -11.088 25.605  37.098  1.00 32.26  ? 71  TRP A CE2 1 
ATOM   460   C  CE3 . TRP A 1 71  ? -9.609  24.926  35.318  1.00 34.32  ? 71  TRP A CE3 1 
ATOM   461   C  CZ2 . TRP A 1 71  ? -10.474 24.733  38.006  1.00 33.75  ? 71  TRP A CZ2 1 
ATOM   462   C  CZ3 . TRP A 1 71  ? -9.028  24.034  36.204  1.00 35.66  ? 71  TRP A CZ3 1 
ATOM   463   C  CH2 . TRP A 1 71  ? -9.460  23.939  37.526  1.00 34.24  ? 71  TRP A CH2 1 
ATOM   464   N  N   . ASP A 1 72  ? -14.516 27.694  33.130  1.00 33.43  ? 72  ASP A N   1 
ATOM   465   C  CA  . ASP A 1 72  ? -15.800 28.197  33.581  1.00 30.32  ? 72  ASP A CA  1 
ATOM   466   C  C   . ASP A 1 72  ? -16.928 27.364  32.977  1.00 34.09  ? 72  ASP A C   1 
ATOM   467   O  O   . ASP A 1 72  ? -17.935 27.187  33.609  1.00 39.92  ? 72  ASP A O   1 
ATOM   468   C  CB  . ASP A 1 72  ? -15.947 29.666  33.261  1.00 28.10  ? 72  ASP A CB  1 
ATOM   469   C  CG  . ASP A 1 72  ? -14.991 30.589  33.994  1.00 28.47  ? 72  ASP A CG  1 
ATOM   470   O  OD1 . ASP A 1 72  ? -14.382 30.150  34.988  1.00 28.64  ? 72  ASP A OD1 1 
ATOM   471   O  OD2 . ASP A 1 72  ? -14.754 31.701  33.478  1.00 27.14  ? 72  ASP A OD2 1 
ATOM   472   N  N   . ARG A 1 73  ? -16.781 26.804  31.782  1.00 33.43  ? 73  ARG A N   1 
ATOM   473   C  CA  . ARG A 1 73  ? -17.805 25.909  31.249  1.00 32.07  ? 73  ARG A CA  1 
ATOM   474   C  C   . ARG A 1 73  ? -17.795 24.551  31.953  1.00 30.41  ? 73  ARG A C   1 
ATOM   475   O  O   . ARG A 1 73  ? -18.803 23.878  31.954  1.00 33.58  ? 73  ARG A O   1 
ATOM   476   C  CB  . ARG A 1 73  ? -17.681 25.715  29.733  1.00 29.28  ? 73  ARG A CB  1 
ATOM   477   C  CG  . ARG A 1 73  ? -17.714 27.035  28.962  1.00 29.03  ? 73  ARG A CG  1 
ATOM   478   C  CD  . ARG A 1 73  ? -17.253 26.908  27.528  1.00 28.52  ? 73  ARG A CD  1 
ATOM   479   N  NE  . ARG A 1 73  ? -17.882 25.762  26.851  1.00 27.91  ? 73  ARG A NE  1 
ATOM   480   C  CZ  . ARG A 1 73  ? -17.540 25.341  25.649  1.00 25.54  ? 73  ARG A CZ  1 
ATOM   481   N  NH1 . ARG A 1 73  ? -16.460 25.838  25.090  1.00 27.91  ? 73  ARG A NH1 1 
ATOM   482   N  NH2 . ARG A 1 73  ? -18.246 24.422  25.011  1.00 27.04  ? 73  ARG A NH2 1 
ATOM   483   N  N   . LEU A 1 74  ? -16.672 24.105  32.504  1.00 30.59  ? 74  LEU A N   1 
ATOM   484   C  CA  . LEU A 1 74  ? -16.554 22.715  32.919  1.00 32.96  ? 74  LEU A CA  1 
ATOM   485   C  C   . LEU A 1 74  ? -16.804 22.550  34.413  1.00 31.20  ? 74  LEU A C   1 
ATOM   486   O  O   . LEU A 1 74  ? -17.155 21.478  34.860  1.00 28.37  ? 74  LEU A O   1 
ATOM   487   C  CB  . LEU A 1 74  ? -15.160 22.181  32.606  1.00 37.19  ? 74  LEU A CB  1 
ATOM   488   C  CG  . LEU A 1 74  ? -14.877 21.945  31.121  1.00 36.56  ? 74  LEU A CG  1 
ATOM   489   C  CD1 . LEU A 1 74  ? -13.380 21.818  30.908  1.00 38.37  ? 74  LEU A CD1 1 
ATOM   490   C  CD2 . LEU A 1 74  ? -15.635 20.720  30.656  1.00 37.26  ? 74  LEU A CD2 1 
ATOM   491   N  N   . PHE A 1 75  ? -16.495 23.580  35.185  1.00 32.84  ? 75  PHE A N   1 
ATOM   492   C  CA  . PHE A 1 75  ? -16.431 23.478  36.633  1.00 35.70  ? 75  PHE A CA  1 
ATOM   493   C  C   . PHE A 1 75  ? -17.119 24.688  37.239  1.00 38.15  ? 75  PHE A C   1 
ATOM   494   O  O   . PHE A 1 75  ? -17.269 25.721  36.573  1.00 40.59  ? 75  PHE A O   1 
ATOM   495   C  CB  . PHE A 1 75  ? -14.988 23.550  37.139  1.00 35.62  ? 75  PHE A CB  1 
ATOM   496   C  CG  . PHE A 1 75  ? -14.076 22.544  36.468  1.00 35.62  ? 75  PHE A CG  1 
ATOM   497   C  CD1 . PHE A 1 75  ? -14.345 21.195  36.547  1.00 39.78  ? 75  PHE A CD1 1 
ATOM   498   C  CD2 . PHE A 1 75  ? -12.988 22.964  35.726  1.00 36.50  ? 75  PHE A CD2 1 
ATOM   499   C  CE1 . PHE A 1 75  ? -13.526 20.275  35.923  1.00 42.66  ? 75  PHE A CE1 1 
ATOM   500   C  CE2 . PHE A 1 75  ? -12.181 22.042  35.097  1.00 39.02  ? 75  PHE A CE2 1 
ATOM   501   C  CZ  . PHE A 1 75  ? -12.457 20.701  35.199  1.00 42.20  ? 75  PHE A CZ  1 
ATOM   502   N  N   . SER A 1 76  ? -17.565 24.591  38.499  1.00 41.74  ? 76  SER A N   1 
ATOM   503   C  CA  . SER A 1 76  ? -18.020 25.819  39.144  1.00 46.03  ? 76  SER A CA  1 
ATOM   504   C  C   . SER A 1 76  ? -17.386 25.916  40.507  1.00 34.72  ? 76  SER A C   1 
ATOM   505   O  O   . SER A 1 76  ? -16.734 25.002  40.977  1.00 33.39  ? 76  SER A O   1 
ATOM   506   C  CB  . SER A 1 76  ? -19.540 26.012  39.176  1.00 55.35  ? 76  SER A CB  1 
ATOM   507   O  OG  . SER A 1 76  ? -20.163 24.757  39.359  1.00 47.62  ? 76  SER A OG  1 
ATOM   508   N  N   . GLY A 1 77  ? -17.509 27.089  41.102  1.00 32.31  ? 77  GLY A N   1 
ATOM   509   C  CA  . GLY A 1 77  ? -16.815 27.345  42.349  1.00 30.07  ? 77  GLY A CA  1 
ATOM   510   C  C   . GLY A 1 77  ? -15.542 28.117  42.057  1.00 30.11  ? 77  GLY A C   1 
ATOM   511   O  O   . GLY A 1 77  ? -15.521 28.897  41.116  1.00 30.54  ? 77  GLY A O   1 
ATOM   512   N  N   . ALA A 1 78  ? -14.510 27.877  42.861  1.00 30.93  ? 78  ALA A N   1 
ATOM   513   C  CA  . ALA A 1 78  ? -13.308 28.694  42.820  1.00 32.76  ? 78  ALA A CA  1 
ATOM   514   C  C   . ALA A 1 78  ? -12.462 28.339  41.595  1.00 30.15  ? 78  ALA A C   1 
ATOM   515   O  O   . ALA A 1 78  ? -12.511 27.201  41.113  1.00 31.64  ? 78  ALA A O   1 
ATOM   516   C  CB  . ALA A 1 78  ? -12.558 28.502  44.120  1.00 34.13  ? 78  ALA A CB  1 
ATOM   517   N  N   . ARG A 1 79  ? -11.812 29.364  41.039  1.00 25.59  ? 79  ARG A N   1 
ATOM   518   C  CA  . ARG A 1 79  ? -10.926 29.238  39.887  1.00 28.16  ? 79  ARG A CA  1 
ATOM   519   C  C   . ARG A 1 79  ? -9.483  29.398  40.341  1.00 30.75  ? 79  ARG A C   1 
ATOM   520   O  O   . ARG A 1 79  ? -9.218  30.033  41.365  1.00 26.20  ? 79  ARG A O   1 
ATOM   521   C  CB  . ARG A 1 79  ? -11.154 30.384  38.896  1.00 28.54  ? 79  ARG A CB  1 
ATOM   522   C  CG  . ARG A 1 79  ? -12.546 30.330  38.333  1.00 30.27  ? 79  ARG A CG  1 
ATOM   523   C  CD  . ARG A 1 79  ? -12.795 31.642  37.640  1.00 29.28  ? 79  ARG A CD  1 
ATOM   524   N  NE  . ARG A 1 79  ? -12.519 31.432  36.231  1.00 27.44  ? 79  ARG A NE  1 
ATOM   525   C  CZ  . ARG A 1 79  ? -11.459 31.869  35.643  1.00 29.07  ? 79  ARG A CZ  1 
ATOM   526   N  NH1 . ARG A 1 79  ? -10.487 32.460  36.340  1.00 27.70  ? 79  ARG A NH1 1 
ATOM   527   N  NH2 . ARG A 1 79  ? -11.356 31.618  34.363  1.00 27.48  ? 79  ARG A NH2 1 
ATOM   528   N  N   . PRO A 1 80  ? -8.485  28.822  39.619  1.00 28.81  ? 80  PRO A N   1 
ATOM   529   C  CA  . PRO A 1 80  ? -7.083  29.143  39.901  1.00 25.74  ? 80  PRO A CA  1 
ATOM   530   C  C   . PRO A 1 80  ? -6.917  30.659  39.839  1.00 23.10  ? 80  PRO A C   1 
ATOM   531   O  O   . PRO A 1 80  ? -7.442  31.298  38.933  1.00 22.80  ? 80  PRO A O   1 
ATOM   532   C  CB  . PRO A 1 80  ? -6.327  28.424  38.797  1.00 24.96  ? 80  PRO A CB  1 
ATOM   533   C  CG  . PRO A 1 80  ? -7.279  27.281  38.412  1.00 25.79  ? 80  PRO A CG  1 
ATOM   534   C  CD  . PRO A 1 80  ? -8.653  27.888  38.499  1.00 26.28  ? 80  PRO A CD  1 
ATOM   535   N  N   . ALA A 1 81  ? -6.184  31.207  40.804  1.00 21.21  ? 81  ALA A N   1 
ATOM   536   C  CA  . ALA A 1 81  ? -5.984  32.641  40.942  1.00 22.49  ? 81  ALA A CA  1 
ATOM   537   C  C   . ALA A 1 81  ? -5.495  33.323  39.655  1.00 23.79  ? 81  ALA A C   1 
ATOM   538   O  O   . ALA A 1 81  ? -5.895  34.429  39.350  1.00 26.87  ? 81  ALA A O   1 
ATOM   539   C  CB  . ALA A 1 81  ? -5.042  32.864  42.092  1.00 22.37  ? 81  ALA A CB  1 
ATOM   540   N  N   . GLY A 1 82  ? -4.635  32.665  38.874  1.00 28.54  ? 82  GLY A N   1 
ATOM   541   C  CA  . GLY A 1 82  ? -3.936  33.327  37.786  1.00 25.43  ? 82  GLY A CA  1 
ATOM   542   C  C   . GLY A 1 82  ? -4.549  33.073  36.408  1.00 22.87  ? 82  GLY A C   1 
ATOM   543   O  O   . GLY A 1 82  ? -3.996  33.536  35.404  1.00 23.31  ? 82  GLY A O   1 
ATOM   544   N  N   . LEU A 1 83  ? -5.667  32.343  36.355  1.00 20.22  ? 83  LEU A N   1 
ATOM   545   C  CA  . LEU A 1 83  ? -6.149  31.831  35.082  1.00 19.89  ? 83  LEU A CA  1 
ATOM   546   C  C   . LEU A 1 83  ? -6.927  32.896  34.320  1.00 20.98  ? 83  LEU A C   1 
ATOM   547   O  O   . LEU A 1 83  ? -7.921  33.338  34.793  1.00 26.82  ? 83  LEU A O   1 
ATOM   548   C  CB  . LEU A 1 83  ? -6.963  30.568  35.337  1.00 20.20  ? 83  LEU A CB  1 
ATOM   549   C  CG  . LEU A 1 83  ? -7.580  29.908  34.102  1.00 22.16  ? 83  LEU A CG  1 
ATOM   550   C  CD1 . LEU A 1 83  ? -6.517  29.508  33.093  1.00 23.56  ? 83  LEU A CD1 1 
ATOM   551   C  CD2 . LEU A 1 83  ? -8.362  28.712  34.489  1.00 24.97  ? 83  LEU A CD2 1 
ATOM   552   N  N   . HIS A 1 84  ? -6.466  33.321  33.153  1.00 23.38  ? 84  HIS A N   1 
ATOM   553   C  CA  . HIS A 1 84  ? -7.110  34.302  32.284  1.00 23.93  ? 84  HIS A CA  1 
ATOM   554   C  C   . HIS A 1 84  ? -6.754  33.948  30.843  1.00 26.79  ? 84  HIS A C   1 
ATOM   555   O  O   . HIS A 1 84  ? -5.887  33.105  30.593  1.00 32.61  ? 84  HIS A O   1 
ATOM   556   C  CB  . HIS A 1 84  ? -6.672  35.742  32.591  1.00 22.24  ? 84  HIS A CB  1 
ATOM   557   C  CG  . HIS A 1 84  ? -5.203  35.908  32.787  1.00 26.85  ? 84  HIS A CG  1 
ATOM   558   N  ND1 . HIS A 1 84  ? -4.600  35.932  34.042  1.00 30.08  ? 84  HIS A ND1 1 
ATOM   559   C  CD2 . HIS A 1 84  ? -4.192  36.032  31.884  1.00 25.29  ? 84  HIS A CD2 1 
ATOM   560   C  CE1 . HIS A 1 84  ? -3.267  36.060  33.896  1.00 27.79  ? 84  HIS A CE1 1 
ATOM   561   N  NE2 . HIS A 1 84  ? -3.000  36.091  32.585  1.00 26.11  ? 84  HIS A NE2 1 
ATOM   562   N  N   . PRO A 1 85  ? -7.428  34.526  29.835  1.00 28.83  ? 85  PRO A N   1 
ATOM   563   C  CA  . PRO A 1 85  ? -7.024  34.343  28.438  1.00 26.76  ? 85  PRO A CA  1 
ATOM   564   C  C   . PRO A 1 85  ? -5.669  34.966  28.215  1.00 25.53  ? 85  PRO A C   1 
ATOM   565   O  O   . PRO A 1 85  ? -5.313  35.936  28.900  1.00 25.22  ? 85  PRO A O   1 
ATOM   566   C  CB  . PRO A 1 85  ? -8.081  35.099  27.677  1.00 28.33  ? 85  PRO A CB  1 
ATOM   567   C  CG  . PRO A 1 85  ? -9.270  35.018  28.618  1.00 30.22  ? 85  PRO A CG  1 
ATOM   568   C  CD  . PRO A 1 85  ? -8.665  35.301  29.971  1.00 29.84  ? 85  PRO A CD  1 
ATOM   569   N  N   . PHE A 1 86  ? -4.911  34.349  27.300  1.00 25.70  ? 86  PHE A N   1 
ATOM   570   C  CA  . PHE A 1 86  ? -3.613  34.873  26.925  1.00 26.52  ? 86  PHE A CA  1 
ATOM   571   C  C   . PHE A 1 86  ? -3.807  36.336  26.539  1.00 24.78  ? 86  PHE A C   1 
ATOM   572   O  O   . PHE A 1 86  ? -4.767  36.615  25.835  1.00 22.30  ? 86  PHE A O   1 
ATOM   573   C  CB  . PHE A 1 86  ? -3.109  33.991  25.779  1.00 26.06  ? 86  PHE A CB  1 
ATOM   574   C  CG  . PHE A 1 86  ? -1.771  34.406  25.202  1.00 26.65  ? 86  PHE A CG  1 
ATOM   575   C  CD1 . PHE A 1 86  ? -1.688  35.435  24.274  1.00 29.42  ? 86  PHE A CD1 1 
ATOM   576   C  CD2 . PHE A 1 86  ? -0.603  33.808  25.606  1.00 28.89  ? 86  PHE A CD2 1 
ATOM   577   C  CE1 . PHE A 1 86  ? -0.461  35.866  23.803  1.00 27.16  ? 86  PHE A CE1 1 
ATOM   578   C  CE2 . PHE A 1 86  ? 0.624   34.234  25.107  1.00 29.09  ? 86  PHE A CE2 1 
ATOM   579   C  CZ  . PHE A 1 86  ? 0.682   35.236  24.188  1.00 26.95  ? 86  PHE A CZ  1 
ATOM   580   N  N   . ARG A 1 87  ? -2.911  37.222  26.997  1.00 25.38  ? 87  ARG A N   1 
ATOM   581   C  CA  . ARG A 1 87  ? -2.983  38.638  26.672  1.00 30.54  ? 87  ARG A CA  1 
ATOM   582   C  C   . ARG A 1 87  ? -2.162  38.949  25.421  1.00 29.84  ? 87  ARG A C   1 
ATOM   583   O  O   . ARG A 1 87  ? -0.944  38.769  25.427  1.00 27.51  ? 87  ARG A O   1 
ATOM   584   C  CB  . ARG A 1 87  ? -2.386  39.557  27.747  1.00 37.74  ? 87  ARG A CB  1 
ATOM   585   C  CG  . ARG A 1 87  ? -2.701  39.176  29.173  1.00 49.84  ? 87  ARG A CG  1 
ATOM   586   C  CD  . ARG A 1 87  ? -2.208  40.243  30.143  1.00 61.57  ? 87  ARG A CD  1 
ATOM   587   N  NE  . ARG A 1 87  ? -3.390  40.243  31.006  1.00 81.45  ? 87  ARG A NE  1 
ATOM   588   C  CZ  . ARG A 1 87  ? -3.544  39.636  32.180  1.00 88.78  ? 87  ARG A CZ  1 
ATOM   589   N  NH1 . ARG A 1 87  ? -2.477  39.293  32.896  1.00 88.64  ? 87  ARG A NH1 1 
ATOM   590   N  NH2 . ARG A 1 87  ? -4.776  39.433  32.643  1.00 82.67  ? 87  ARG A NH2 1 
ATOM   591   N  N   . GLU A 1 88  ? -2.873  39.406  24.372  1.00 33.22  ? 88  GLU A N   1 
ATOM   592   C  CA  . GLU A 1 88  ? -2.303  39.961  23.161  1.00 31.90  ? 88  GLU A CA  1 
ATOM   593   C  C   . GLU A 1 88  ? -1.295  41.018  23.542  1.00 30.42  ? 88  GLU A C   1 
ATOM   594   O  O   . GLU A 1 88  ? -1.486  41.663  24.547  1.00 30.83  ? 88  GLU A O   1 
ATOM   595   C  CB  . GLU A 1 88  ? -3.323  40.655  22.273  1.00 37.67  ? 88  GLU A CB  1 
ATOM   596   C  CG  . GLU A 1 88  ? -4.159  39.650  21.492  1.00 45.03  ? 88  GLU A CG  1 
ATOM   597   C  CD  . GLU A 1 88  ? -4.382  40.114  20.085  1.00 54.92  ? 88  GLU A CD  1 
ATOM   598   O  OE1 . GLU A 1 88  ? -3.969  39.361  19.185  1.00 68.90  ? 88  GLU A OE1 1 
ATOM   599   O  OE2 . GLU A 1 88  ? -4.900  41.241  19.930  1.00 62.04  ? 88  GLU A OE2 1 
ATOM   600   N  N   . LEU A 1 89  ? -0.196  41.128  22.784  1.00 33.14  ? 89  LEU A N   1 
ATOM   601   C  CA  . LEU A 1 89  ? 0.806   42.170  22.983  1.00 35.47  ? 89  LEU A CA  1 
ATOM   602   C  C   . LEU A 1 89  ? 1.015   42.852  21.644  1.00 34.55  ? 89  LEU A C   1 
ATOM   603   O  O   . LEU A 1 89  ? 1.407   42.210  20.685  1.00 34.68  ? 89  LEU A O   1 
ATOM   604   C  CB  . LEU A 1 89  ? 2.148   41.708  23.548  1.00 38.84  ? 89  LEU A CB  1 
ATOM   605   C  CG  . LEU A 1 89  ? 2.108   40.991  24.905  1.00 36.17  ? 89  LEU A CG  1 
ATOM   606   C  CD1 . LEU A 1 89  ? 3.495   40.545  25.365  1.00 34.23  ? 89  LEU A CD1 1 
ATOM   607   C  CD2 . LEU A 1 89  ? 1.488   41.856  25.994  1.00 36.57  ? 89  LEU A CD2 1 
ATOM   608   N  N   . ASP A 1 90  ? 0.690   44.141  21.607  1.00 37.42  ? 90  ASP A N   1 
ATOM   609   C  CA  . ASP A 1 90  ? 0.747   44.955  20.408  1.00 38.01  ? 90  ASP A CA  1 
ATOM   610   C  C   . ASP A 1 90  ? 1.956   45.844  20.513  1.00 34.74  ? 90  ASP A C   1 
ATOM   611   O  O   . ASP A 1 90  ? 1.871   46.934  21.055  1.00 38.05  ? 90  ASP A O   1 
ATOM   612   C  CB  . ASP A 1 90  ? -0.545  45.722  20.201  1.00 43.04  ? 90  ASP A CB  1 
ATOM   613   C  CG  . ASP A 1 90  ? -1.370  45.109  19.087  1.00 59.40  ? 90  ASP A CG  1 
ATOM   614   O  OD1 . ASP A 1 90  ? -0.982  45.353  17.909  1.00 77.75  ? 90  ASP A OD1 1 
ATOM   615   O  OD2 . ASP A 1 90  ? -2.294  44.300  19.400  1.00 71.52  ? 90  ASP A OD2 1 
ATOM   616   N  N   . GLY A 1 91  ? 3.115   45.332  20.094  1.00 35.68  ? 91  GLY A N   1 
ATOM   617   C  CA  . GLY A 1 91  ? 4.356   46.075  20.229  1.00 32.99  ? 91  GLY A CA  1 
ATOM   618   C  C   . GLY A 1 91  ? 4.487   47.018  19.043  1.00 35.65  ? 91  GLY A C   1 
ATOM   619   O  O   . GLY A 1 91  ? 3.764   46.883  18.047  1.00 40.19  ? 91  GLY A O   1 
ATOM   620   N  N   . PRO A 1 92  ? 5.380   48.022  19.117  1.00 37.93  ? 92  PRO A N   1 
ATOM   621   C  CA  . PRO A 1 92  ? 5.614   48.926  17.996  1.00 39.82  ? 92  PRO A CA  1 
ATOM   622   C  C   . PRO A 1 92  ? 5.896   48.163  16.700  1.00 44.46  ? 92  PRO A C   1 
ATOM   623   O  O   . PRO A 1 92  ? 5.420   48.576  15.669  1.00 48.46  ? 92  PRO A O   1 
ATOM   624   C  CB  . PRO A 1 92  ? 6.808   49.790  18.417  1.00 41.47  ? 92  PRO A CB  1 
ATOM   625   C  CG  . PRO A 1 92  ? 7.328   49.215  19.722  1.00 44.52  ? 92  PRO A CG  1 
ATOM   626   C  CD  . PRO A 1 92  ? 6.218   48.324  20.280  1.00 46.64  ? 92  PRO A CD  1 
ATOM   627   N  N   . VAL A 1 93  ? 6.659   47.059  16.760  1.00 39.60  ? 93  VAL A N   1 
ATOM   628   C  CA  . VAL A 1 93  ? 7.062   46.309  15.578  1.00 32.60  ? 93  VAL A CA  1 
ATOM   629   C  C   . VAL A 1 93  ? 6.439   44.914  15.568  1.00 33.35  ? 93  VAL A C   1 
ATOM   630   O  O   . VAL A 1 93  ? 5.995   44.441  14.544  1.00 35.56  ? 93  VAL A O   1 
ATOM   631   C  CB  . VAL A 1 93  ? 8.594   46.203  15.585  1.00 32.34  ? 93  VAL A CB  1 
ATOM   632   C  CG1 . VAL A 1 93  ? 9.080   45.285  14.484  1.00 32.62  ? 93  VAL A CG1 1 
ATOM   633   C  CG2 . VAL A 1 93  ? 9.279   47.547  15.508  1.00 32.06  ? 93  VAL A CG2 1 
ATOM   634   N  N   . HIS A 1 94  ? 6.484   44.219  16.703  1.00 37.59  ? 94  HIS A N   1 
ATOM   635   C  CA  . HIS A 1 94  ? 6.109   42.816  16.785  1.00 35.67  ? 94  HIS A CA  1 
ATOM   636   C  C   . HIS A 1 94  ? 4.880   42.654  17.677  1.00 35.16  ? 94  HIS A C   1 
ATOM   637   O  O   . HIS A 1 94  ? 4.768   43.324  18.705  1.00 35.52  ? 94  HIS A O   1 
ATOM   638   C  CB  . HIS A 1 94  ? 7.272   41.970  17.341  1.00 32.09  ? 94  HIS A CB  1 
ATOM   639   C  CG  . HIS A 1 94  ? 8.523   42.011  16.532  1.00 28.71  ? 94  HIS A CG  1 
ATOM   640   N  ND1 . HIS A 1 94  ? 8.580   41.526  15.241  1.00 25.70  ? 94  HIS A ND1 1 
ATOM   641   C  CD2 . HIS A 1 94  ? 9.715   42.530  16.808  1.00 27.43  ? 94  HIS A CD2 1 
ATOM   642   C  CE1 . HIS A 1 94  ? 9.784   41.739  14.762  1.00 24.06  ? 94  HIS A CE1 1 
ATOM   643   N  NE2 . HIS A 1 94  ? 10.486  42.346  15.692  1.00 27.60  ? 94  HIS A NE2 1 
ATOM   644   N  N   . ARG A 1 95  ? 4.040   41.670  17.327  1.00 36.11  ? 95  ARG A N   1 
ATOM   645   C  CA  . ARG A 1 95  ? 2.765   41.419  17.981  1.00 36.61  ? 95  ARG A CA  1 
ATOM   646   C  C   . ARG A 1 95  ? 2.662   39.962  18.446  1.00 31.55  ? 95  ARG A C   1 
ATOM   647   O  O   . ARG A 1 95  ? 2.992   39.036  17.713  1.00 29.09  ? 95  ARG A O   1 
ATOM   648   C  CB  . ARG A 1 95  ? 1.701   41.809  16.967  1.00 50.34  ? 95  ARG A CB  1 
ATOM   649   C  CG  . ARG A 1 95  ? 1.775   43.223  16.365  1.00 81.96  ? 95  ARG A CG  1 
ATOM   650   C  CD  . ARG A 1 95  ? 0.661   43.594  15.331  1.00 86.75  ? 95  ARG A CD  1 
ATOM   651   N  NE  . ARG A 1 95  ? -0.582  43.416  16.094  1.00 107.72 ? 95  ARG A NE  1 
ATOM   652   C  CZ  . ARG A 1 95  ? -1.010  42.209  16.537  1.00 98.70  ? 95  ARG A CZ  1 
ATOM   653   N  NH1 . ARG A 1 95  ? -0.962  41.163  15.728  1.00 68.11  ? 95  ARG A NH1 1 
ATOM   654   N  NH2 . ARG A 1 95  ? -1.553  42.059  17.746  1.00 100.40 ? 95  ARG A NH2 1 
ATOM   655   N  N   . ALA A 1 96  ? 2.248   39.749  19.691  1.00 26.99  ? 96  ALA A N   1 
ATOM   656   C  CA  . ALA A 1 96  ? 2.010   38.409  20.192  1.00 27.37  ? 96  ALA A CA  1 
ATOM   657   C  C   . ALA A 1 96  ? 0.523   38.151  20.120  1.00 28.07  ? 96  ALA A C   1 
ATOM   658   O  O   . ALA A 1 96  ? -0.245  38.742  20.849  1.00 35.39  ? 96  ALA A O   1 
ATOM   659   C  CB  . ALA A 1 96  ? 2.544   38.236  21.609  1.00 29.32  ? 96  ALA A CB  1 
ATOM   660   N  N   . VAL A 1 97  ? 0.096   37.290  19.213  1.00 30.72  ? 97  VAL A N   1 
ATOM   661   C  CA  . VAL A 1 97  ? -1.325  37.084  18.997  1.00 30.47  ? 97  VAL A CA  1 
ATOM   662   C  C   . VAL A 1 97  ? -1.810  36.061  20.011  1.00 28.38  ? 97  VAL A C   1 
ATOM   663   O  O   . VAL A 1 97  ? -0.987  35.280  20.555  1.00 30.96  ? 97  VAL A O   1 
ATOM   664   C  CB  . VAL A 1 97  ? -1.626  36.569  17.578  1.00 32.03  ? 97  VAL A CB  1 
ATOM   665   C  CG1 . VAL A 1 97  ? -1.125  37.547  16.555  1.00 34.56  ? 97  VAL A CG1 1 
ATOM   666   C  CG2 . VAL A 1 97  ? -1.045  35.176  17.280  1.00 34.86  ? 97  VAL A CG2 1 
ATOM   667   N  N   . ALA A 1 98  ? -3.142  36.107  20.183  1.00 23.01  ? 98  ALA A N   1 
ATOM   668   C  CA  . ALA A 1 98  ? -3.881  35.164  21.000  1.00 23.32  ? 98  ALA A CA  1 
ATOM   669   C  C   . ALA A 1 98  ? -4.797  34.339  20.116  1.00 24.72  ? 98  ALA A C   1 
ATOM   670   O  O   . ALA A 1 98  ? -5.542  34.891  19.325  1.00 26.40  ? 98  ALA A O   1 
ATOM   671   C  CB  . ALA A 1 98  ? -4.690  35.892  22.032  1.00 24.47  ? 98  ALA A CB  1 
ATOM   672   N  N   . THR A 1 99  ? -4.756  33.016  20.243  1.00 22.96  ? 99  THR A N   1 
ATOM   673   C  CA  . THR A 1 99  ? -5.543  32.166  19.378  1.00 21.87  ? 99  THR A CA  1 
ATOM   674   C  C   . THR A 1 99  ? -6.334  31.226  20.260  1.00 23.87  ? 99  THR A C   1 
ATOM   675   O  O   . THR A 1 99  ? -6.048  31.061  21.427  1.00 24.41  ? 99  THR A O   1 
ATOM   676   C  CB  . THR A 1 99  ? -4.664  31.438  18.371  1.00 22.88  ? 99  THR A CB  1 
ATOM   677   O  OG1 . THR A 1 99  ? -3.731  30.663  19.119  1.00 22.85  ? 99  THR A OG1 1 
ATOM   678   C  CG2 . THR A 1 99  ? -3.933  32.427  17.491  1.00 23.22  ? 99  THR A CG2 1 
ATOM   679   N  N   . PRO A 1 100 ? -7.430  30.655  19.744  1.00 27.37  ? 100 PRO A N   1 
ATOM   680   C  CA  . PRO A 1 100 ? -8.309  29.819  20.541  1.00 30.71  ? 100 PRO A CA  1 
ATOM   681   C  C   . PRO A 1 100 ? -7.653  28.521  20.974  1.00 30.78  ? 100 PRO A C   1 
ATOM   682   O  O   . PRO A 1 100 ? -6.925  27.889  20.208  1.00 30.79  ? 100 PRO A O   1 
ATOM   683   C  CB  . PRO A 1 100 ? -9.464  29.505  19.563  1.00 30.38  ? 100 PRO A CB  1 
ATOM   684   C  CG  . PRO A 1 100 ? -9.379  30.544  18.501  1.00 29.16  ? 100 PRO A CG  1 
ATOM   685   C  CD  . PRO A 1 100 ? -7.898  30.802  18.362  1.00 29.20  ? 100 PRO A CD  1 
ATOM   686   N  N   . GLY A 1 101 ? -8.036  28.116  22.170  1.00 29.12  ? 101 GLY A N   1 
ATOM   687   C  CA  . GLY A 1 101 ? -7.647  26.842  22.697  1.00 29.58  ? 101 GLY A CA  1 
ATOM   688   C  C   . GLY A 1 101 ? -8.268  26.637  24.064  1.00 26.97  ? 101 GLY A C   1 
ATOM   689   O  O   . GLY A 1 101 ? -8.009  27.388  24.989  1.00 26.74  ? 101 GLY A O   1 
ATOM   690   N  N   . ASP A 1 102 ? -9.052  25.570  24.184  1.00 27.40  ? 102 ASP A N   1 
ATOM   691   C  CA  . ASP A 1 102 ? -9.675  25.246  25.448  1.00 24.95  ? 102 ASP A CA  1 
ATOM   692   C  C   . ASP A 1 102 ? -8.887  24.174  26.189  1.00 23.93  ? 102 ASP A C   1 
ATOM   693   O  O   . ASP A 1 102 ? -8.806  24.206  27.401  1.00 24.76  ? 102 ASP A O   1 
ATOM   694   C  CB  . ASP A 1 102 ? -11.114 24.807  25.240  1.00 24.34  ? 102 ASP A CB  1 
ATOM   695   C  CG  . ASP A 1 102 ? -11.995 25.900  24.667  1.00 24.48  ? 102 ASP A CG  1 
ATOM   696   O  OD1 . ASP A 1 102 ? -11.775 27.055  25.063  1.00 23.21  ? 102 ASP A OD1 1 
ATOM   697   O  OD2 . ASP A 1 102 ? -12.896 25.562  23.875  1.00 24.13  ? 102 ASP A OD2 1 
ATOM   698   N  N   . LEU A 1 103 ? -8.397  23.179  25.472  1.00 21.83  ? 103 LEU A N   1 
ATOM   699   C  CA  . LEU A 1 103 ? -7.663  22.096  26.084  1.00 23.27  ? 103 LEU A CA  1 
ATOM   700   C  C   . LEU A 1 103 ? -6.330  21.989  25.389  1.00 23.49  ? 103 LEU A C   1 
ATOM   701   O  O   . LEU A 1 103 ? -6.244  22.214  24.178  1.00 23.90  ? 103 LEU A O   1 
ATOM   702   C  CB  . LEU A 1 103 ? -8.387  20.774  25.908  1.00 25.50  ? 103 LEU A CB  1 
ATOM   703   C  CG  . LEU A 1 103 ? -9.708  20.633  26.661  1.00 27.91  ? 103 LEU A CG  1 
ATOM   704   C  CD1 . LEU A 1 103 ? -10.265 19.270  26.321  1.00 30.06  ? 103 LEU A CD1 1 
ATOM   705   C  CD2 . LEU A 1 103 ? -9.550  20.771  28.134  1.00 26.92  ? 103 LEU A CD2 1 
ATOM   706   N  N   . LEU A 1 104 ? -5.330  21.632  26.202  1.00 26.54  ? 104 LEU A N   1 
ATOM   707   C  CA  . LEU A 1 104 ? -3.971  21.366  25.755  1.00 23.00  ? 104 LEU A CA  1 
ATOM   708   C  C   . LEU A 1 104 ? -3.628  19.938  26.174  1.00 23.64  ? 104 LEU A C   1 
ATOM   709   O  O   . LEU A 1 104 ? -3.820  19.558  27.322  1.00 19.55  ? 104 LEU A O   1 
ATOM   710   C  CB  . LEU A 1 104 ? -2.998  22.348  26.389  1.00 22.46  ? 104 LEU A CB  1 
ATOM   711   C  CG  . LEU A 1 104 ? -1.527  21.988  26.193  1.00 25.54  ? 104 LEU A CG  1 
ATOM   712   C  CD1 . LEU A 1 104 ? -1.028  22.202  24.793  1.00 23.09  ? 104 LEU A CD1 1 
ATOM   713   C  CD2 . LEU A 1 104 ? -0.694  22.832  27.116  1.00 29.53  ? 104 LEU A CD2 1 
ATOM   714   N  N   . PHE A 1 105 ? -3.122  19.138  25.227  1.00 23.85  ? 105 PHE A N   1 
ATOM   715   C  CA  . PHE A 1 105 ? -2.439  17.898  25.546  1.00 22.73  ? 105 PHE A CA  1 
ATOM   716   C  C   . PHE A 1 105 ? -0.982  18.041  25.112  1.00 22.60  ? 105 PHE A C   1 
ATOM   717   O  O   . PHE A 1 105 ? -0.704  18.217  23.945  1.00 22.57  ? 105 PHE A O   1 
ATOM   718   C  CB  . PHE A 1 105 ? -3.141  16.715  24.899  1.00 23.13  ? 105 PHE A CB  1 
ATOM   719   C  CG  . PHE A 1 105 ? -4.603  16.599  25.300  1.00 24.52  ? 105 PHE A CG  1 
ATOM   720   C  CD1 . PHE A 1 105 ? -4.958  16.006  26.514  1.00 29.13  ? 105 PHE A CD1 1 
ATOM   721   C  CD2 . PHE A 1 105 ? -5.612  17.122  24.503  1.00 25.47  ? 105 PHE A CD2 1 
ATOM   722   C  CE1 . PHE A 1 105 ? -6.287  15.893  26.898  1.00 28.82  ? 105 PHE A CE1 1 
ATOM   723   C  CE2 . PHE A 1 105 ? -6.941  17.008  24.885  1.00 27.68  ? 105 PHE A CE2 1 
ATOM   724   C  CZ  . PHE A 1 105 ? -7.271  16.405  26.080  1.00 28.38  ? 105 PHE A CZ  1 
ATOM   725   N  N   . HIS A 1 106 ? -0.073  18.058  26.091  1.00 23.90  ? 106 HIS A N   1 
ATOM   726   C  CA  . HIS A 1 106 ? 1.353   18.115  25.871  1.00 22.11  ? 106 HIS A CA  1 
ATOM   727   C  C   . HIS A 1 106 ? 1.889   16.718  26.130  1.00 23.61  ? 106 HIS A C   1 
ATOM   728   O  O   . HIS A 1 106 ? 2.089   16.327  27.291  1.00 25.55  ? 106 HIS A O   1 
ATOM   729   C  CB  . HIS A 1 106 ? 1.973   19.153  26.808  1.00 22.45  ? 106 HIS A CB  1 
ATOM   730   C  CG  . HIS A 1 106 ? 3.458   19.307  26.638  1.00 21.28  ? 106 HIS A CG  1 
ATOM   731   N  ND1 . HIS A 1 106 ? 4.266   19.808  27.631  1.00 19.59  ? 106 HIS A ND1 1 
ATOM   732   C  CD2 . HIS A 1 106 ? 4.270   18.989  25.604  1.00 22.68  ? 106 HIS A CD2 1 
ATOM   733   C  CE1 . HIS A 1 106 ? 5.518   19.806  27.207  1.00 22.59  ? 106 HIS A CE1 1 
ATOM   734   N  NE2 . HIS A 1 106 ? 5.540   19.328  25.978  1.00 25.41  ? 106 HIS A NE2 1 
ATOM   735   N  N   . ILE A 1 107 ? 2.086   15.990  25.021  1.00 21.58  ? 107 ILE A N   1 
ATOM   736   C  CA  . ILE A 1 107 ? 2.398   14.574  25.060  1.00 20.59  ? 107 ILE A CA  1 
ATOM   737   C  C   . ILE A 1 107 ? 3.862   14.416  24.670  1.00 21.75  ? 107 ILE A C   1 
ATOM   738   O  O   . ILE A 1 107 ? 4.266   14.940  23.637  1.00 21.14  ? 107 ILE A O   1 
ATOM   739   C  CB  . ILE A 1 107 ? 1.496   13.790  24.110  1.00 21.34  ? 107 ILE A CB  1 
ATOM   740   C  CG1 . ILE A 1 107 ? 0.023   14.049  24.399  1.00 25.03  ? 107 ILE A CG1 1 
ATOM   741   C  CG2 . ILE A 1 107 ? 1.851   12.296  24.142  1.00 22.39  ? 107 ILE A CG2 1 
ATOM   742   C  CD1 . ILE A 1 107 ? -0.903  13.501  23.329  1.00 26.85  ? 107 ILE A CD1 1 
ATOM   743   N  N   . ARG A 1 108 ? 4.638   13.696  25.498  1.00 19.99  ? 108 ARG A N   1 
ATOM   744   C  CA  . ARG A 1 108 ? 6.079   13.611  25.325  1.00 20.36  ? 108 ARG A CA  1 
ATOM   745   C  C   . ARG A 1 108 ? 6.499   12.164  25.534  1.00 21.95  ? 108 ARG A C   1 
ATOM   746   O  O   . ARG A 1 108 ? 5.976   11.502  26.422  1.00 22.02  ? 108 ARG A O   1 
ATOM   747   C  CB  . ARG A 1 108 ? 6.837   14.462  26.352  1.00 22.63  ? 108 ARG A CB  1 
ATOM   748   C  CG  . ARG A 1 108 ? 6.809   15.943  26.021  1.00 25.21  ? 108 ARG A CG  1 
ATOM   749   C  CD  . ARG A 1 108 ? 7.468   16.754  27.126  1.00 26.34  ? 108 ARG A CD  1 
ATOM   750   N  NE  . ARG A 1 108 ? 6.691   16.722  28.364  1.00 29.61  ? 108 ARG A NE  1 
ATOM   751   C  CZ  . ARG A 1 108 ? 6.922   17.530  29.393  1.00 31.03  ? 108 ARG A CZ  1 
ATOM   752   N  NH1 . ARG A 1 108 ? 7.952   18.343  29.333  1.00 31.19  ? 108 ARG A NH1 1 
ATOM   753   N  NH2 . ARG A 1 108 ? 6.143   17.559  30.478  1.00 36.09  ? 108 ARG A NH2 1 
ATOM   754   N  N   . ALA A 1 109 ? 7.482   11.714  24.757  1.00 22.43  ? 109 ALA A N   1 
ATOM   755   C  CA  . ALA A 1 109 ? 8.096   10.427  24.978  1.00 24.59  ? 109 ALA A CA  1 
ATOM   756   C  C   . ALA A 1 109 ? 9.451   10.368  24.284  1.00 26.10  ? 109 ALA A C   1 
ATOM   757   O  O   . ALA A 1 109 ? 9.845   11.280  23.551  1.00 26.33  ? 109 ALA A O   1 
ATOM   758   C  CB  . ALA A 1 109 ? 7.168   9.362   24.433  1.00 25.51  ? 109 ALA A CB  1 
ATOM   759   N  N   . SER A 1 110 ? 10.112  9.224   24.453  1.00 26.05  ? 110 SER A N   1 
ATOM   760   C  CA  . SER A 1 110 ? 11.351  8.975   23.756  1.00 29.03  ? 110 SER A CA  1 
ATOM   761   C  C   . SER A 1 110 ? 11.132  8.602   22.293  1.00 34.09  ? 110 SER A C   1 
ATOM   762   O  O   . SER A 1 110 ? 12.089  8.673   21.535  1.00 42.16  ? 110 SER A O   1 
ATOM   763   C  CB  . SER A 1 110 ? 12.103  7.923   24.448  1.00 30.17  ? 110 SER A CB  1 
ATOM   764   O  OG  . SER A 1 110 ? 11.458  6.668   24.295  1.00 32.40  ? 110 SER A OG  1 
ATOM   765   N  N   . ARG A 1 111 ? 9.909   8.231   21.870  1.00 35.78  ? 111 ARG A N   1 
ATOM   766   C  CA  . ARG A 1 111 ? 9.652   7.898   20.474  1.00 38.63  ? 111 ARG A CA  1 
ATOM   767   C  C   . ARG A 1 111 ? 8.309   8.476   20.050  1.00 33.08  ? 111 ARG A C   1 
ATOM   768   O  O   . ARG A 1 111 ? 7.362   8.450   20.836  1.00 30.74  ? 111 ARG A O   1 
ATOM   769   C  CB  . ARG A 1 111 ? 9.507   6.375   20.304  1.00 47.90  ? 111 ARG A CB  1 
ATOM   770   C  CG  . ARG A 1 111 ? 10.560  5.448   20.901  1.00 53.65  ? 111 ARG A CG  1 
ATOM   771   C  CD  . ARG A 1 111 ? 9.972   4.116   21.330  1.00 65.89  ? 111 ARG A CD  1 
ATOM   772   N  NE  . ARG A 1 111 ? 9.149   3.357   20.372  1.00 87.38  ? 111 ARG A NE  1 
ATOM   773   C  CZ  . ARG A 1 111 ? 8.484   2.210   20.680  1.00 89.38  ? 111 ARG A CZ  1 
ATOM   774   N  NH1 . ARG A 1 111 ? 8.257   1.871   21.950  1.00 64.43  ? 111 ARG A NH1 1 
ATOM   775   N  NH2 . ARG A 1 111 ? 8.019   1.405   19.717  1.00 94.31  ? 111 ARG A NH2 1 
ATOM   776   N  N   . LEU A 1 112 ? 8.203   8.925   18.794  1.00 27.99  ? 112 LEU A N   1 
ATOM   777   C  CA  . LEU A 1 112 ? 6.977   9.546   18.315  1.00 28.11  ? 112 LEU A CA  1 
ATOM   778   C  C   . LEU A 1 112 ? 5.764   8.619   18.408  1.00 27.43  ? 112 LEU A C   1 
ATOM   779   O  O   . LEU A 1 112 ? 4.675   9.053   18.700  1.00 33.03  ? 112 LEU A O   1 
ATOM   780   C  CB  . LEU A 1 112 ? 7.190   9.999   16.881  1.00 28.37  ? 112 LEU A CB  1 
ATOM   781   C  CG  . LEU A 1 112 ? 6.094   10.897  16.305  1.00 30.66  ? 112 LEU A CG  1 
ATOM   782   C  CD1 . LEU A 1 112 ? 5.812   12.064  17.172  1.00 30.60  ? 112 LEU A CD1 1 
ATOM   783   C  CD2 . LEU A 1 112 ? 6.529   11.456  14.972  1.00 37.17  ? 112 LEU A CD2 1 
ATOM   784   N  N   . ASP A 1 113 ? 5.930   7.335   18.165  1.00 26.76  ? 113 ASP A N   1 
ATOM   785   C  CA  . ASP A 1 113 ? 4.814   6.449   18.010  1.00 28.66  ? 113 ASP A CA  1 
ATOM   786   C  C   . ASP A 1 113 ? 4.074   6.305   19.326  1.00 30.02  ? 113 ASP A C   1 
ATOM   787   O  O   . ASP A 1 113 ? 2.867   6.134   19.295  1.00 33.51  ? 113 ASP A O   1 
ATOM   788   C  CB  . ASP A 1 113 ? 5.230   5.066   17.567  1.00 35.56  ? 113 ASP A CB  1 
ATOM   789   C  CG  . ASP A 1 113 ? 6.259   4.378   18.440  1.00 37.57  ? 113 ASP A CG  1 
ATOM   790   O  OD1 . ASP A 1 113 ? 7.429   4.806   18.397  1.00 56.31  ? 113 ASP A OD1 1 
ATOM   791   O  OD2 . ASP A 1 113 ? 5.875   3.411   19.112  1.00 38.06  ? 113 ASP A OD2 1 
ATOM   792   N  N   . LEU A 1 114 ? 4.771   6.343   20.462  1.00 26.58  ? 114 LEU A N   1 
ATOM   793   C  CA  . LEU A 1 114 ? 4.089   6.340   21.760  1.00 28.50  ? 114 LEU A CA  1 
ATOM   794   C  C   . LEU A 1 114 ? 3.193   7.580   21.924  1.00 26.07  ? 114 LEU A C   1 
ATOM   795   O  O   . LEU A 1 114 ? 2.089   7.469   22.443  1.00 25.97  ? 114 LEU A O   1 
ATOM   796   C  CB  . LEU A 1 114 ? 5.061   6.294   22.926  1.00 28.34  ? 114 LEU A CB  1 
ATOM   797   C  CG  . LEU A 1 114 ? 5.854   4.996   23.073  1.00 30.76  ? 114 LEU A CG  1 
ATOM   798   C  CD1 . LEU A 1 114 ? 6.931   5.132   24.166  1.00 27.86  ? 114 LEU A CD1 1 
ATOM   799   C  CD2 . LEU A 1 114 ? 4.922   3.802   23.332  1.00 33.55  ? 114 LEU A CD2 1 
ATOM   800   N  N   . CYS A 1 115 ? 3.715   8.746   21.521  1.00 21.82  ? 115 CYS A N   1 
ATOM   801   C  CA  . CYS A 1 115 ? 2.955   9.974   21.533  1.00 21.21  ? 115 CYS A CA  1 
ATOM   802   C  C   . CYS A 1 115 ? 1.724   9.827   20.667  1.00 20.22  ? 115 CYS A C   1 
ATOM   803   O  O   . CYS A 1 115 ? 0.633   10.225  21.043  1.00 20.41  ? 115 CYS A O   1 
ATOM   804   C  CB  . CYS A 1 115 ? 3.781   11.127  20.998  1.00 22.75  ? 115 CYS A CB  1 
ATOM   805   S  SG  . CYS A 1 115 ? 5.211   11.485  22.049  1.00 25.52  ? 115 CYS A SG  1 
ATOM   806   N  N   . PHE A 1 116 ? 1.906   9.254   19.501  1.00 22.34  ? 116 PHE A N   1 
ATOM   807   C  CA  . PHE A 1 116 ? 0.833   9.183   18.523  1.00 24.50  ? 116 PHE A CA  1 
ATOM   808   C  C   . PHE A 1 116 ? -0.244  8.208   18.996  1.00 23.99  ? 116 PHE A C   1 
ATOM   809   O  O   . PHE A 1 116 ? -1.435  8.439   18.785  1.00 24.78  ? 116 PHE A O   1 
ATOM   810   C  CB  . PHE A 1 116 ? 1.447   8.776   17.182  1.00 23.46  ? 116 PHE A CB  1 
ATOM   811   C  CG  . PHE A 1 116 ? 0.475   8.920   16.039  1.00 23.23  ? 116 PHE A CG  1 
ATOM   812   C  CD1 . PHE A 1 116 ? 0.394   10.109  15.351  1.00 24.31  ? 116 PHE A CD1 1 
ATOM   813   C  CD2 . PHE A 1 116 ? -0.336  7.859   15.657  1.00 24.42  ? 116 PHE A CD2 1 
ATOM   814   C  CE1 . PHE A 1 116 ? -0.527  10.248  14.332  1.00 27.27  ? 116 PHE A CE1 1 
ATOM   815   C  CE2 . PHE A 1 116 ? -1.264  8.005   14.647  1.00 25.75  ? 116 PHE A CE2 1 
ATOM   816   C  CZ  . PHE A 1 116 ? -1.357  9.198   13.988  1.00 26.42  ? 116 PHE A CZ  1 
ATOM   817   N  N   . ALA A 1 117 ? 0.181   7.114   19.633  1.00 25.35  ? 117 ALA A N   1 
ATOM   818   C  CA  . ALA A 1 117 ? -0.766  6.112   20.095  1.00 25.27  ? 117 ALA A CA  1 
ATOM   819   C  C   . ALA A 1 117 ? -1.661  6.723   21.173  1.00 28.02  ? 117 ALA A C   1 
ATOM   820   O  O   . ALA A 1 117 ? -2.876  6.517   21.166  1.00 27.38  ? 117 ALA A O   1 
ATOM   821   C  CB  . ALA A 1 117 ? -0.037  4.900   20.635  1.00 25.84  ? 117 ALA A CB  1 
ATOM   822   N  N   . LEU A 1 118 ? -1.060  7.475   22.098  1.00 26.31  ? 118 LEU A N   1 
ATOM   823   C  CA  . LEU A 1 118 ? -1.815  8.123   23.160  1.00 27.13  ? 118 LEU A CA  1 
ATOM   824   C  C   . LEU A 1 118 ? -2.723  9.215   22.586  1.00 25.13  ? 118 LEU A C   1 
ATOM   825   O  O   . LEU A 1 118 ? -3.885  9.319   22.959  1.00 26.86  ? 118 LEU A O   1 
ATOM   826   C  CB  . LEU A 1 118 ? -0.881  8.660   24.247  1.00 25.29  ? 118 LEU A CB  1 
ATOM   827   C  CG  . LEU A 1 118 ? -1.557  9.309   25.451  1.00 26.81  ? 118 LEU A CG  1 
ATOM   828   C  CD1 . LEU A 1 118 ? -2.534  8.394   26.044  1.00 28.75  ? 118 LEU A CD1 1 
ATOM   829   C  CD2 . LEU A 1 118 ? -0.641  9.700   26.602  1.00 30.76  ? 118 LEU A CD2 1 
ATOM   830   N  N   . ALA A 1 119 ? -2.222  10.035  21.672  1.00 27.58  ? 119 ALA A N   1 
ATOM   831   C  CA  . ALA A 1 119 ? -3.064  11.064  21.057  1.00 25.41  ? 119 ALA A CA  1 
ATOM   832   C  C   . ALA A 1 119 ? -4.276  10.432  20.366  1.00 27.04  ? 119 ALA A C   1 
ATOM   833   O  O   . ALA A 1 119 ? -5.382  10.958  20.441  1.00 27.19  ? 119 ALA A O   1 
ATOM   834   C  CB  . ALA A 1 119 ? -2.252  11.886  20.078  1.00 25.88  ? 119 ALA A CB  1 
ATOM   835   N  N   . THR A 1 120 ? -4.058  9.311   19.674  1.00 23.71  ? 120 THR A N   1 
ATOM   836   C  CA  . THR A 1 120 ? -5.124  8.614   19.000  1.00 26.05  ? 120 THR A CA  1 
ATOM   837   C  C   . THR A 1 120 ? -6.196  8.215   20.010  1.00 28.05  ? 120 THR A C   1 
ATOM   838   O  O   . THR A 1 120 ? -7.381  8.359   19.737  1.00 30.18  ? 120 THR A O   1 
ATOM   839   C  CB  . THR A 1 120 ? -4.581  7.377   18.293  1.00 30.62  ? 120 THR A CB  1 
ATOM   840   O  OG1 . THR A 1 120 ? -3.730  7.870   17.263  1.00 32.99  ? 120 THR A OG1 1 
ATOM   841   C  CG2 . THR A 1 120 ? -5.682  6.559   17.635  1.00 31.80  ? 120 THR A CG2 1 
ATOM   842   N  N   . GLU A 1 121 ? -5.789  7.649   21.147  1.00 25.23  ? 121 GLU A N   1 
ATOM   843   C  CA  . GLU A 1 121 ? -6.760  7.212   22.138  1.00 28.43  ? 121 GLU A CA  1 
ATOM   844   C  C   . GLU A 1 121 ? -7.525  8.410   22.693  1.00 28.53  ? 121 GLU A C   1 
ATOM   845   O  O   . GLU A 1 121 ? -8.721  8.340   22.904  1.00 29.45  ? 121 GLU A O   1 
ATOM   846   C  CB  . GLU A 1 121 ? -6.149  6.473   23.334  1.00 32.74  ? 121 GLU A CB  1 
ATOM   847   C  CG  . GLU A 1 121 ? -5.670  5.065   23.002  1.00 35.72  ? 121 GLU A CG  1 
ATOM   848   C  CD  . GLU A 1 121 ? -6.805  4.059   22.855  1.00 39.04  ? 121 GLU A CD  1 
ATOM   849   O  OE1 . GLU A 1 121 ? -7.968  4.376   23.193  1.00 48.17  ? 121 GLU A OE1 1 
ATOM   850   O  OE2 . GLU A 1 121 ? -6.515  2.910   22.437  1.00 39.57  ? 121 GLU A OE2 1 
ATOM   851   N  N   . ILE A 1 122 ? -6.832  9.501   22.982  1.00 28.32  ? 122 ILE A N   1 
ATOM   852   C  CA  . ILE A 1 122 ? -7.484  10.655  23.567  1.00 29.14  ? 122 ILE A CA  1 
ATOM   853   C  C   . ILE A 1 122 ? -8.497  11.189  22.557  1.00 29.56  ? 122 ILE A C   1 
ATOM   854   O  O   . ILE A 1 122 ? -9.662  11.352  22.895  1.00 26.35  ? 122 ILE A O   1 
ATOM   855   C  CB  . ILE A 1 122 ? -6.436  11.701  23.999  1.00 27.52  ? 122 ILE A CB  1 
ATOM   856   C  CG1 . ILE A 1 122 ? -5.697  11.235  25.235  1.00 28.48  ? 122 ILE A CG1 1 
ATOM   857   C  CG2 . ILE A 1 122 ? -7.062  13.073  24.212  1.00 26.10  ? 122 ILE A CG2 1 
ATOM   858   C  CD1 . ILE A 1 122 ? -4.411  11.981  25.502  1.00 30.18  ? 122 ILE A CD1 1 
ATOM   859   N  N   . MET A 1 123 ? -8.081  11.454  21.312  1.00 30.86  ? 123 MET A N   1 
ATOM   860   C  CA  . MET A 1 123 ? -8.988  12.070  20.356  1.00 29.77  ? 123 MET A CA  1 
ATOM   861   C  C   . MET A 1 123 ? -10.135 11.137  19.968  1.00 29.12  ? 123 MET A C   1 
ATOM   862   O  O   . MET A 1 123 ? -11.174 11.603  19.520  1.00 31.27  ? 123 MET A O   1 
ATOM   863   C  CB  . MET A 1 123 ? -8.235  12.460  19.098  1.00 33.01  ? 123 MET A CB  1 
ATOM   864   C  CG  . MET A 1 123 ? -7.365  13.651  19.335  1.00 41.09  ? 123 MET A CG  1 
ATOM   865   S  SD  . MET A 1 123 ? -8.310  15.151  19.582  1.00 47.26  ? 123 MET A SD  1 
ATOM   866   C  CE  . MET A 1 123 ? -9.473  15.023  18.214  1.00 51.07  ? 123 MET A CE  1 
ATOM   867   N  N   . GLY A 1 124 ? -9.922  9.832   20.101  1.00 26.55  ? 124 GLY A N   1 
ATOM   868   C  CA  . GLY A 1 124 ? -10.952 8.847   19.864  1.00 26.27  ? 124 GLY A CA  1 
ATOM   869   C  C   . GLY A 1 124 ? -12.094 8.995   20.852  1.00 27.78  ? 124 GLY A C   1 
ATOM   870   O  O   . GLY A 1 124 ? -13.218 8.864   20.445  1.00 30.15  ? 124 GLY A O   1 
ATOM   871   N  N   . ARG A 1 125 ? -11.800 9.309   22.118  1.00 32.16  ? 125 ARG A N   1 
ATOM   872   C  CA  . ARG A 1 125 ? -12.797 9.491   23.161  1.00 28.03  ? 125 ARG A CA  1 
ATOM   873   C  C   . ARG A 1 125 ? -13.479 10.844  23.024  1.00 24.37  ? 125 ARG A C   1 
ATOM   874   O  O   . ARG A 1 125 ? -14.528 11.062  23.596  1.00 28.70  ? 125 ARG A O   1 
ATOM   875   C  CB  . ARG A 1 125 ? -12.139 9.433   24.535  1.00 31.63  ? 125 ARG A CB  1 
ATOM   876   C  CG  . ARG A 1 125 ? -11.382 8.142   24.840  1.00 41.15  ? 125 ARG A CG  1 
ATOM   877   C  CD  . ARG A 1 125 ? -12.094 6.997   25.534  1.00 53.04  ? 125 ARG A CD  1 
ATOM   878   N  NE  . ARG A 1 125 ? -12.970 7.571   26.571  1.00 68.49  ? 125 ARG A NE  1 
ATOM   879   C  CZ  . ARG A 1 125 ? -12.765 7.493   27.879  1.00 66.63  ? 125 ARG A CZ  1 
ATOM   880   N  NH1 . ARG A 1 125 ? -11.956 6.542   28.299  1.00 68.56  ? 125 ARG A NH1 1 
ATOM   881   N  NH2 . ARG A 1 125 ? -13.368 8.317   28.743  1.00 60.12  ? 125 ARG A NH2 1 
ATOM   882   N  N   . LEU A 1 126 ? -12.881 11.770  22.303  1.00 25.86  ? 126 LEU A N   1 
ATOM   883   C  CA  . LEU A 1 126 ? -13.389 13.133  22.257  1.00 29.05  ? 126 LEU A CA  1 
ATOM   884   C  C   . LEU A 1 126 ? -14.019 13.426  20.912  1.00 34.06  ? 126 LEU A C   1 
ATOM   885   O  O   . LEU A 1 126 ? -14.499 14.539  20.768  1.00 34.41  ? 126 LEU A O   1 
ATOM   886   C  CB  . LEU A 1 126 ? -12.277 14.158  22.496  1.00 28.99  ? 126 LEU A CB  1 
ATOM   887   C  CG  . LEU A 1 126 ? -11.632 14.169  23.885  1.00 29.71  ? 126 LEU A CG  1 
ATOM   888   C  CD1 . LEU A 1 126 ? -10.537 15.216  23.915  1.00 32.36  ? 126 LEU A CD1 1 
ATOM   889   C  CD2 . LEU A 1 126 ? -12.628 14.414  25.005  1.00 31.13  ? 126 LEU A CD2 1 
ATOM   890   N  N   . ARG A 1 127 ? -13.969 12.481  19.940  1.00 43.81  ? 127 ARG A N   1 
ATOM   891   C  CA  . ARG A 1 127 ? -14.565 12.658  18.611  1.00 51.17  ? 127 ARG A CA  1 
ATOM   892   C  C   . ARG A 1 127 ? -15.976 13.194  18.824  1.00 46.37  ? 127 ARG A C   1 
ATOM   893   O  O   . ARG A 1 127 ? -16.714 12.689  19.668  1.00 45.95  ? 127 ARG A O   1 
ATOM   894   C  CB  . ARG A 1 127 ? -14.618 11.316  17.848  1.00 69.64  ? 127 ARG A CB  1 
ATOM   895   C  CG  . ARG A 1 127 ? -14.540 11.179  16.327  1.00 84.47  ? 127 ARG A CG  1 
ATOM   896   C  CD  . ARG A 1 127 ? -13.421 10.261  15.783  1.00 91.51  ? 127 ARG A CD  1 
ATOM   897   N  NE  . ARG A 1 127 ? -12.203 11.087  15.651  1.00 108.36 ? 127 ARG A NE  1 
ATOM   898   C  CZ  . ARG A 1 127 ? -10.912 10.753  15.848  1.00 94.85  ? 127 ARG A CZ  1 
ATOM   899   N  NH1 . ARG A 1 127 ? -10.561 9.489   16.033  1.00 90.77  ? 127 ARG A NH1 1 
ATOM   900   N  NH2 . ARG A 1 127 ? -9.961  11.688  15.856  1.00 74.10  ? 127 ARG A NH2 1 
ATOM   901   N  N   . GLY A 1 128 ? -16.344 14.266  18.127  1.00 41.09  ? 128 GLY A N   1 
ATOM   902   C  CA  . GLY A 1 128 ? -17.697 14.772  18.261  1.00 36.10  ? 128 GLY A CA  1 
ATOM   903   C  C   . GLY A 1 128 ? -17.869 15.830  19.348  1.00 36.49  ? 128 GLY A C   1 
ATOM   904   O  O   . GLY A 1 128 ? -18.796 16.595  19.284  1.00 40.74  ? 128 GLY A O   1 
ATOM   905   N  N   . ALA A 1 129 ? -16.969 15.941  20.315  1.00 38.95  ? 129 ALA A N   1 
ATOM   906   C  CA  . ALA A 1 129 ? -17.110 16.931  21.387  1.00 31.52  ? 129 ALA A CA  1 
ATOM   907   C  C   . ALA A 1 129 ? -16.181 18.126  21.236  1.00 28.64  ? 129 ALA A C   1 
ATOM   908   O  O   . ALA A 1 129 ? -16.363 19.131  21.912  1.00 26.02  ? 129 ALA A O   1 
ATOM   909   C  CB  . ALA A 1 129 ? -16.817 16.274  22.722  1.00 34.28  ? 129 ALA A CB  1 
ATOM   910   N  N   . VAL A 1 130 ? -15.142 18.008  20.399  1.00 27.99  ? 130 VAL A N   1 
ATOM   911   C  CA  . VAL A 1 130 ? -14.081 18.994  20.337  1.00 30.38  ? 130 VAL A CA  1 
ATOM   912   C  C   . VAL A 1 130 ? -13.724 19.240  18.880  1.00 27.11  ? 130 VAL A C   1 
ATOM   913   O  O   . VAL A 1 130 ? -14.064 18.447  18.023  1.00 29.85  ? 130 VAL A O   1 
ATOM   914   C  CB  . VAL A 1 130 ? -12.831 18.552  21.119  1.00 32.18  ? 130 VAL A CB  1 
ATOM   915   C  CG1 . VAL A 1 130 ? -13.141 18.174  22.562  1.00 33.38  ? 130 VAL A CG1 1 
ATOM   916   C  CG2 . VAL A 1 130 ? -12.137 17.382  20.433  1.00 36.60  ? 130 VAL A CG2 1 
ATOM   917   N  N   . THR A 1 131 ? -13.031 20.340  18.623  1.00 24.71  ? 131 THR A N   1 
ATOM   918   C  CA  . THR A 1 131 ? -12.604 20.684  17.289  1.00 26.32  ? 131 THR A CA  1 
ATOM   919   C  C   . THR A 1 131 ? -11.101 20.955  17.367  1.00 26.54  ? 131 THR A C   1 
ATOM   920   O  O   . THR A 1 131 ? -10.653 21.780  18.169  1.00 27.23  ? 131 THR A O   1 
ATOM   921   C  CB  . THR A 1 131 ? -13.392 21.903  16.779  1.00 30.87  ? 131 THR A CB  1 
ATOM   922   O  OG1 . THR A 1 131 ? -14.715 21.413  16.593  1.00 33.71  ? 131 THR A OG1 1 
ATOM   923   C  CG2 . THR A 1 131 ? -12.864 22.456  15.466  1.00 30.55  ? 131 THR A CG2 1 
ATOM   924   N  N   . PRO A 1 132 ? -10.274 20.319  16.519  1.00 26.61  ? 132 PRO A N   1 
ATOM   925   C  CA  . PRO A 1 132 ? -8.836  20.531  16.574  1.00 27.94  ? 132 PRO A CA  1 
ATOM   926   C  C   . PRO A 1 132 ? -8.514  21.947  16.116  1.00 27.66  ? 132 PRO A C   1 
ATOM   927   O  O   . PRO A 1 132 ? -9.060  22.402  15.128  1.00 22.72  ? 132 PRO A O   1 
ATOM   928   C  CB  . PRO A 1 132 ? -8.306  19.469  15.595  1.00 30.58  ? 132 PRO A CB  1 
ATOM   929   C  CG  . PRO A 1 132 ? -9.457  18.512  15.416  1.00 29.55  ? 132 PRO A CG  1 
ATOM   930   C  CD  . PRO A 1 132 ? -10.656 19.401  15.447  1.00 28.13  ? 132 PRO A CD  1 
ATOM   931   N  N   . GLN A 1 133 ? -7.650  22.633  16.862  1.00 26.88  ? 133 GLN A N   1 
ATOM   932   C  CA  . GLN A 1 133 ? -7.126  23.915  16.451  1.00 26.79  ? 133 GLN A CA  1 
ATOM   933   C  C   . GLN A 1 133 ? -5.667  23.843  16.022  1.00 25.23  ? 133 GLN A C   1 
ATOM   934   O  O   . GLN A 1 133 ? -5.261  24.664  15.228  1.00 29.96  ? 133 GLN A O   1 
ATOM   935   C  CB  . GLN A 1 133 ? -7.032  24.893  17.616  1.00 34.99  ? 133 GLN A CB  1 
ATOM   936   C  CG  . GLN A 1 133 ? -8.374  25.250  18.229  1.00 43.12  ? 133 GLN A CG  1 
ATOM   937   C  CD  . GLN A 1 133 ? -9.272  25.889  17.205  1.00 45.89  ? 133 GLN A CD  1 
ATOM   938   O  OE1 . GLN A 1 133 ? -8.807  26.766  16.466  1.00 43.92  ? 133 GLN A OE1 1 
ATOM   939   N  NE2 . GLN A 1 133 ? -10.517 25.413  17.130  1.00 58.46  ? 133 GLN A NE2 1 
ATOM   940   N  N   . ASP A 1 134 ? -4.830  23.016  16.657  1.00 24.07  ? 134 ASP A N   1 
ATOM   941   C  CA  . ASP A 1 134 ? -3.407  22.941  16.339  1.00 23.36  ? 134 ASP A CA  1 
ATOM   942   C  C   . ASP A 1 134 ? -2.918  21.523  16.668  1.00 23.24  ? 134 ASP A C   1 
ATOM   943   O  O   . ASP A 1 134 ? -3.348  20.925  17.646  1.00 25.18  ? 134 ASP A O   1 
ATOM   944   C  CB  . ASP A 1 134 ? -2.615  24.034  17.039  1.00 22.94  ? 134 ASP A CB  1 
ATOM   945   C  CG  . ASP A 1 134 ? -1.272  24.386  16.421  1.00 27.14  ? 134 ASP A CG  1 
ATOM   946   O  OD1 . ASP A 1 134 ? -1.062  24.030  15.278  1.00 31.40  ? 134 ASP A OD1 1 
ATOM   947   O  OD2 . ASP A 1 134 ? -0.412  24.981  17.090  1.00 33.59  ? 134 ASP A OD2 1 
ATOM   948   N  N   . GLU A 1 135 ? -2.091  20.957  15.798  1.00 19.94  ? 135 GLU A N   1 
ATOM   949   C  CA  . GLU A 1 135 ? -1.441  19.681  16.036  1.00 20.41  ? 135 GLU A CA  1 
ATOM   950   C  C   . GLU A 1 135 ? -0.002  19.782  15.520  1.00 23.67  ? 135 GLU A C   1 
ATOM   951   O  O   . GLU A 1 135 ? 0.209   20.085  14.362  1.00 27.08  ? 135 GLU A O   1 
ATOM   952   C  CB  . GLU A 1 135 ? -2.161  18.578  15.280  1.00 20.33  ? 135 GLU A CB  1 
ATOM   953   C  CG  . GLU A 1 135 ? -1.551  17.215  15.586  1.00 24.33  ? 135 GLU A CG  1 
ATOM   954   C  CD  . GLU A 1 135 ? -2.236  16.061  14.872  1.00 26.44  ? 135 GLU A CD  1 
ATOM   955   O  OE1 . GLU A 1 135 ? -3.211  16.393  14.151  1.00 32.02  ? 135 GLU A OE1 1 
ATOM   956   O  OE2 . GLU A 1 135 ? -1.815  14.882  15.028  1.00 25.12  ? 135 GLU A OE2 1 
ATOM   957   N  N   . VAL A 1 136 ? 0.998   19.614  16.384  1.00 23.60  ? 136 VAL A N   1 
ATOM   958   C  CA  . VAL A 1 136 ? 2.392   19.755  16.004  1.00 20.93  ? 136 VAL A CA  1 
ATOM   959   C  C   . VAL A 1 136 ? 3.132   18.521  16.502  1.00 21.58  ? 136 VAL A C   1 
ATOM   960   O  O   . VAL A 1 136 ? 2.961   18.102  17.654  1.00 23.00  ? 136 VAL A O   1 
ATOM   961   C  CB  . VAL A 1 136 ? 2.985   21.044  16.576  1.00 21.66  ? 136 VAL A CB  1 
ATOM   962   C  CG1 . VAL A 1 136 ? 4.478   21.138  16.397  1.00 25.38  ? 136 VAL A CG1 1 
ATOM   963   C  CG2 . VAL A 1 136 ? 2.362   22.279  15.966  1.00 24.78  ? 136 VAL A CG2 1 
ATOM   964   N  N   . HIS A 1 137 ? 3.900   17.909  15.581  1.00 20.97  ? 137 HIS A N   1 
ATOM   965   C  CA  . HIS A 1 137 ? 4.741   16.778  15.896  1.00 21.22  ? 137 HIS A CA  1 
ATOM   966   C  C   . HIS A 1 137 ? 6.155   17.321  15.954  1.00 24.16  ? 137 HIS A C   1 
ATOM   967   O  O   . HIS A 1 137 ? 6.671   17.824  14.958  1.00 24.66  ? 137 HIS A O   1 
ATOM   968   C  CB  . HIS A 1 137 ? 4.584   15.684  14.858  1.00 22.90  ? 137 HIS A CB  1 
ATOM   969   C  CG  . HIS A 1 137 ? 3.207   15.122  14.743  1.00 25.44  ? 137 HIS A CG  1 
ATOM   970   N  ND1 . HIS A 1 137 ? 2.921   14.093  13.868  1.00 27.25  ? 137 HIS A ND1 1 
ATOM   971   C  CD2 . HIS A 1 137 ? 2.035   15.474  15.303  1.00 28.13  ? 137 HIS A CD2 1 
ATOM   972   C  CE1 . HIS A 1 137 ? 1.638   13.790  13.964  1.00 28.39  ? 137 HIS A CE1 1 
ATOM   973   N  NE2 . HIS A 1 137 ? 1.079   14.623  14.829  1.00 27.57  ? 137 HIS A NE2 1 
ATOM   974   N  N   . GLY A 1 138 ? 6.718   17.347  17.164  1.00 24.39  ? 138 GLY A N   1 
ATOM   975   C  CA  . GLY A 1 138 ? 8.023   17.929  17.388  1.00 21.58  ? 138 GLY A CA  1 
ATOM   976   C  C   . GLY A 1 138 ? 9.083   16.850  17.521  1.00 21.58  ? 138 GLY A C   1 
ATOM   977   O  O   . GLY A 1 138 ? 8.789   15.723  17.954  1.00 18.33  ? 138 GLY A O   1 
ATOM   978   N  N   . PHE A 1 139 ? 10.319  17.220  17.148  1.00 23.26  ? 139 PHE A N   1 
ATOM   979   C  CA  . PHE A 1 139 ? 11.468  16.330  17.289  1.00 23.83  ? 139 PHE A CA  1 
ATOM   980   C  C   . PHE A 1 139 ? 12.685  17.127  17.767  1.00 21.80  ? 139 PHE A C   1 
ATOM   981   O  O   . PHE A 1 139 ? 12.911  18.210  17.285  1.00 23.13  ? 139 PHE A O   1 
ATOM   982   C  CB  . PHE A 1 139 ? 11.630  15.629  15.937  1.00 22.34  ? 139 PHE A CB  1 
ATOM   983   C  CG  . PHE A 1 139 ? 11.735  16.571  14.760  1.00 23.54  ? 139 PHE A CG  1 
ATOM   984   C  CD1 . PHE A 1 139 ? 12.948  17.160  14.429  1.00 29.53  ? 139 PHE A CD1 1 
ATOM   985   C  CD2 . PHE A 1 139 ? 10.644  16.832  13.950  1.00 27.90  ? 139 PHE A CD2 1 
ATOM   986   C  CE1 . PHE A 1 139 ? 13.047  18.050  13.361  1.00 31.47  ? 139 PHE A CE1 1 
ATOM   987   C  CE2 . PHE A 1 139 ? 10.755  17.690  12.847  1.00 31.41  ? 139 PHE A CE2 1 
ATOM   988   C  CZ  . PHE A 1 139 ? 11.945  18.320  12.571  1.00 29.19  ? 139 PHE A CZ  1 
ATOM   989   N  N   . LYS A 1 140 ? 13.489  16.561  18.669  1.00 29.74  ? 140 LYS A N   1 
ATOM   990   C  CA  . LYS A 1 140 ? 14.805  17.080  19.036  1.00 32.90  ? 140 LYS A CA  1 
ATOM   991   C  C   . LYS A 1 140 ? 15.758  16.935  17.860  1.00 28.57  ? 140 LYS A C   1 
ATOM   992   O  O   . LYS A 1 140 ? 15.664  16.010  17.052  1.00 31.68  ? 140 LYS A O   1 
ATOM   993   C  CB  . LYS A 1 140 ? 15.455  16.316  20.205  1.00 48.96  ? 140 LYS A CB  1 
ATOM   994   C  CG  . LYS A 1 140 ? 16.955  15.772  20.099  1.00 61.07  ? 140 LYS A CG  1 
ATOM   995   C  CD  . LYS A 1 140 ? 17.454  14.845  21.242  1.00 54.46  ? 140 LYS A CD  1 
ATOM   996   C  CE  . LYS A 1 140 ? 18.941  14.805  21.586  1.00 47.37  ? 140 LYS A CE  1 
ATOM   997   N  N   . TYR A 1 141 ? 16.637  17.913  17.740  1.00 31.33  ? 141 TYR A N   1 
ATOM   998   C  CA  . TYR A 1 141 ? 17.408  18.146  16.531  1.00 33.27  ? 141 TYR A CA  1 
ATOM   999   C  C   . TYR A 1 141 ? 18.809  17.997  17.005  1.00 32.15  ? 141 TYR A C   1 
ATOM   1000  O  O   . TYR A 1 141 ? 19.272  18.893  17.654  1.00 38.39  ? 141 TYR A O   1 
ATOM   1001  C  CB  . TYR A 1 141 ? 17.057  19.557  16.041  1.00 36.08  ? 141 TYR A CB  1 
ATOM   1002  C  CG  . TYR A 1 141 ? 17.404  19.942  14.626  1.00 39.90  ? 141 TYR A CG  1 
ATOM   1003  C  CD1 . TYR A 1 141 ? 16.972  19.202  13.551  1.00 44.95  ? 141 TYR A CD1 1 
ATOM   1004  C  CD2 . TYR A 1 141 ? 18.150  21.076  14.381  1.00 51.88  ? 141 TYR A CD2 1 
ATOM   1005  C  CE1 . TYR A 1 141 ? 17.292  19.560  12.265  1.00 53.44  ? 141 TYR A CE1 1 
ATOM   1006  C  CE2 . TYR A 1 141 ? 18.513  21.440  13.098  1.00 58.20  ? 141 TYR A CE2 1 
ATOM   1007  C  CZ  . TYR A 1 141 ? 18.081  20.669  12.036  1.00 63.93  ? 141 TYR A CZ  1 
ATOM   1008  O  OH  . TYR A 1 141 ? 18.431  20.966  10.754  1.00 66.56  ? 141 TYR A OH  1 
ATOM   1009  N  N   . PHE A 1 142 ? 19.423  16.832  16.865  1.00 43.45  ? 142 PHE A N   1 
ATOM   1010  C  CA  . PHE A 1 142 ? 20.880  16.790  16.986  1.00 50.77  ? 142 PHE A CA  1 
ATOM   1011  C  C   . PHE A 1 142 ? 21.167  16.781  18.477  1.00 40.14  ? 142 PHE A C   1 
ATOM   1012  O  O   . PHE A 1 142 ? 20.681  15.880  19.156  1.00 46.37  ? 142 PHE A O   1 
ATOM   1013  C  CB  . PHE A 1 142 ? 21.807  17.842  16.297  1.00 48.64  ? 142 PHE A CB  1 
ATOM   1014  C  CG  . PHE A 1 142 ? 21.936  17.607  14.794  1.00 51.89  ? 142 PHE A CG  1 
ATOM   1015  C  CD1 . PHE A 1 142 ? 22.777  16.596  14.292  1.00 53.57  ? 142 PHE A CD1 1 
ATOM   1016  C  CD2 . PHE A 1 142 ? 21.164  18.349  13.893  1.00 48.70  ? 142 PHE A CD2 1 
ATOM   1017  C  CE1 . PHE A 1 142 ? 22.804  16.331  12.930  1.00 58.67  ? 142 PHE A CE1 1 
ATOM   1018  C  CE2 . PHE A 1 142 ? 21.205  18.089  12.530  1.00 47.03  ? 142 PHE A CE2 1 
ATOM   1019  C  CZ  . PHE A 1 142 ? 22.014  17.075  12.050  1.00 53.80  ? 142 PHE A CZ  1 
ATOM   1020  N  N   . ASP A 1 143 ? 21.862  17.821  18.952  1.00 28.85  ? 143 ASP A N   1 
ATOM   1021  C  CA  . ASP A 1 143 ? 22.302  17.873  20.317  1.00 28.72  ? 143 ASP A CA  1 
ATOM   1022  C  C   . ASP A 1 143 ? 21.593  19.015  21.013  1.00 28.47  ? 143 ASP A C   1 
ATOM   1023  O  O   . ASP A 1 143 ? 22.193  20.023  21.384  1.00 27.09  ? 143 ASP A O   1 
ATOM   1024  C  CB  . ASP A 1 143 ? 23.805  18.018  20.390  1.00 34.26  ? 143 ASP A CB  1 
ATOM   1025  C  CG  . ASP A 1 143 ? 24.362  19.099  19.484  1.00 44.38  ? 143 ASP A CG  1 
ATOM   1026  O  OD1 . ASP A 1 143 ? 23.810  19.191  18.345  1.00 46.58  ? 143 ASP A OD1 1 
ATOM   1027  O  OD2 . ASP A 1 143 ? 25.304  19.810  19.960  1.00 41.62  ? 143 ASP A OD2 1 
ATOM   1028  N  N   . GLU A 1 144 ? 20.296  18.794  21.175  1.00 31.20  ? 144 GLU A N   1 
ATOM   1029  C  CA  . GLU A 1 144 ? 19.383  19.716  21.832  1.00 30.79  ? 144 GLU A CA  1 
ATOM   1030  C  C   . GLU A 1 144 ? 19.377  21.073  21.152  1.00 26.53  ? 144 GLU A C   1 
ATOM   1031  O  O   . GLU A 1 144 ? 18.968  22.044  21.779  1.00 26.17  ? 144 GLU A O   1 
ATOM   1032  C  CB  . GLU A 1 144 ? 19.701  19.803  23.328  1.00 33.67  ? 144 GLU A CB  1 
ATOM   1033  C  CG  . GLU A 1 144 ? 19.530  18.449  24.012  1.00 35.02  ? 144 GLU A CG  1 
ATOM   1034  C  CD  . GLU A 1 144 ? 18.087  18.011  24.085  1.00 35.07  ? 144 GLU A CD  1 
ATOM   1035  O  OE1 . GLU A 1 144 ? 17.080  18.794  24.041  1.00 39.26  ? 144 GLU A OE1 1 
ATOM   1036  O  OE2 . GLU A 1 144 ? 18.049  16.772  24.131  1.00 43.34  ? 144 GLU A OE2 1 
ATOM   1037  N  N   . ARG A 1 145 ? 19.720  21.128  19.862  1.00 24.88  ? 145 ARG A N   1 
ATOM   1038  C  CA  . ARG A 1 145 ? 19.619  22.384  19.132  1.00 25.30  ? 145 ARG A CA  1 
ATOM   1039  C  C   . ARG A 1 145 ? 18.207  22.664  18.611  1.00 25.26  ? 145 ARG A C   1 
ATOM   1040  O  O   . ARG A 1 145 ? 17.378  21.785  18.445  1.00 26.65  ? 145 ARG A O   1 
ATOM   1041  C  CB  . ARG A 1 145 ? 20.668  22.442  18.027  1.00 25.55  ? 145 ARG A CB  1 
ATOM   1042  C  CG  . ARG A 1 145 ? 22.040  22.332  18.670  1.00 25.43  ? 145 ARG A CG  1 
ATOM   1043  C  CD  . ARG A 1 145 ? 23.097  22.717  17.724  1.00 26.82  ? 145 ARG A CD  1 
ATOM   1044  N  NE  . ARG A 1 145 ? 24.403  22.467  18.323  1.00 24.30  ? 145 ARG A NE  1 
ATOM   1045  C  CZ  . ARG A 1 145 ? 25.181  23.403  18.854  1.00 24.77  ? 145 ARG A CZ  1 
ATOM   1046  N  NH1 . ARG A 1 145 ? 24.894  24.703  18.802  1.00 26.78  ? 145 ARG A NH1 1 
ATOM   1047  N  NH2 . ARG A 1 145 ? 26.229  22.998  19.536  1.00 22.24  ? 145 ARG A NH2 1 
ATOM   1048  N  N   . ASP A 1 146 ? 17.936  23.947  18.383  1.00 23.88  ? 146 ASP A N   1 
ATOM   1049  C  CA  . ASP A 1 146 ? 16.667  24.352  17.838  1.00 23.23  ? 146 ASP A CA  1 
ATOM   1050  C  C   . ASP A 1 146 ? 16.904  24.679  16.382  1.00 24.08  ? 146 ASP A C   1 
ATOM   1051  O  O   . ASP A 1 146 ? 17.974  24.460  15.852  1.00 21.24  ? 146 ASP A O   1 
ATOM   1052  C  CB  . ASP A 1 146 ? 16.038  25.473  18.648  1.00 23.89  ? 146 ASP A CB  1 
ATOM   1053  C  CG  . ASP A 1 146 ? 16.864  26.736  18.718  1.00 24.46  ? 146 ASP A CG  1 
ATOM   1054  O  OD1 . ASP A 1 146 ? 17.689  26.930  17.806  1.00 22.26  ? 146 ASP A OD1 1 
ATOM   1055  O  OD2 . ASP A 1 146 ? 16.703  27.448  19.716  1.00 27.83  ? 146 ASP A OD2 1 
ATOM   1056  N  N   . MET A 1 147 ? 15.881  25.209  15.760  1.00 28.24  ? 147 MET A N   1 
ATOM   1057  C  CA  . MET A 1 147 ? 15.896  25.405  14.324  1.00 30.20  ? 147 MET A CA  1 
ATOM   1058  C  C   . MET A 1 147 ? 16.833  26.550  13.954  1.00 24.86  ? 147 MET A C   1 
ATOM   1059  O  O   . MET A 1 147 ? 17.246  26.639  12.815  1.00 22.40  ? 147 MET A O   1 
ATOM   1060  C  CB  . MET A 1 147 ? 14.474  25.667  13.816  1.00 36.67  ? 147 MET A CB  1 
ATOM   1061  C  CG  . MET A 1 147 ? 14.310  25.230  12.409  1.00 38.88  ? 147 MET A CG  1 
ATOM   1062  S  SD  . MET A 1 147 ? 14.545  23.457  12.198  1.00 43.65  ? 147 MET A SD  1 
ATOM   1063  C  CE  . MET A 1 147 ? 12.836  22.913  12.233  1.00 41.32  ? 147 MET A CE  1 
ATOM   1064  N  N   . LEU A 1 148 ? 17.228  27.401  14.902  1.00 22.41  ? 148 LEU A N   1 
ATOM   1065  C  CA  . LEU A 1 148 ? 18.212  28.435  14.614  1.00 23.72  ? 148 LEU A CA  1 
ATOM   1066  C  C   . LEU A 1 148 ? 19.640  27.936  14.851  1.00 20.34  ? 148 LEU A C   1 
ATOM   1067  O  O   . LEU A 1 148 ? 20.570  28.698  14.705  1.00 20.86  ? 148 LEU A O   1 
ATOM   1068  C  CB  . LEU A 1 148 ? 17.938  29.640  15.509  1.00 26.31  ? 148 LEU A CB  1 
ATOM   1069  C  CG  . LEU A 1 148 ? 16.532  30.237  15.459  1.00 28.27  ? 148 LEU A CG  1 
ATOM   1070  C  CD1 . LEU A 1 148 ? 16.437  31.291  16.536  1.00 28.89  ? 148 LEU A CD1 1 
ATOM   1071  C  CD2 . LEU A 1 148 ? 16.242  30.798  14.077  1.00 29.91  ? 148 LEU A CD2 1 
ATOM   1072  N  N   . GLY A 1 149 ? 19.810  26.696  15.278  1.00 19.14  ? 149 GLY A N   1 
ATOM   1073  C  CA  . GLY A 1 149 ? 21.117  26.097  15.364  1.00 22.44  ? 149 GLY A CA  1 
ATOM   1074  C  C   . GLY A 1 149 ? 21.805  26.281  16.718  1.00 24.74  ? 149 GLY A C   1 
ATOM   1075  O  O   . GLY A 1 149 ? 22.957  25.876  16.870  1.00 26.21  ? 149 GLY A O   1 
ATOM   1076  N  N   . PHE A 1 150 ? 21.088  26.827  17.707  1.00 27.22  ? 150 PHE A N   1 
ATOM   1077  C  CA  . PHE A 1 150 ? 21.600  27.023  19.055  1.00 23.88  ? 150 PHE A CA  1 
ATOM   1078  C  C   . PHE A 1 150 ? 21.055  25.962  20.014  1.00 25.27  ? 150 PHE A C   1 
ATOM   1079  O  O   . PHE A 1 150 ? 19.917  25.519  19.865  1.00 27.02  ? 150 PHE A O   1 
ATOM   1080  C  CB  . PHE A 1 150 ? 21.212  28.394  19.594  1.00 23.16  ? 150 PHE A CB  1 
ATOM   1081  C  CG  . PHE A 1 150 ? 22.106  29.503  19.072  1.00 21.95  ? 150 PHE A CG  1 
ATOM   1082  C  CD1 . PHE A 1 150 ? 22.004  29.925  17.762  1.00 22.01  ? 150 PHE A CD1 1 
ATOM   1083  C  CD2 . PHE A 1 150 ? 23.034  30.122  19.889  1.00 21.22  ? 150 PHE A CD2 1 
ATOM   1084  C  CE1 . PHE A 1 150 ? 22.840  30.932  17.291  1.00 24.32  ? 150 PHE A CE1 1 
ATOM   1085  C  CE2 . PHE A 1 150 ? 23.860  31.122  19.406  1.00 20.12  ? 150 PHE A CE2 1 
ATOM   1086  C  CZ  . PHE A 1 150 ? 23.785  31.502  18.107  1.00 21.01  ? 150 PHE A CZ  1 
ATOM   1087  N  N   . VAL A 1 151 ? 21.854  25.591  21.025  1.00 25.59  ? 151 VAL A N   1 
ATOM   1088  C  CA  . VAL A 1 151 ? 21.387  24.686  22.059  1.00 23.22  ? 151 VAL A CA  1 
ATOM   1089  C  C   . VAL A 1 151 ? 20.313  25.415  22.857  1.00 26.01  ? 151 VAL A C   1 
ATOM   1090  O  O   . VAL A 1 151 ? 20.488  26.581  23.233  1.00 25.33  ? 151 VAL A O   1 
ATOM   1091  C  CB  . VAL A 1 151 ? 22.529  24.228  22.983  1.00 23.51  ? 151 VAL A CB  1 
ATOM   1092  C  CG1 . VAL A 1 151 ? 22.054  23.241  24.022  1.00 24.50  ? 151 VAL A CG1 1 
ATOM   1093  C  CG2 . VAL A 1 151 ? 23.716  23.673  22.225  1.00 22.18  ? 151 VAL A CG2 1 
ATOM   1094  N  N   . ASP A 1 152 ? 19.229  24.677  23.124  1.00 29.59  ? 152 ASP A N   1 
ATOM   1095  C  CA  . ASP A 1 152 ? 17.964  25.195  23.615  1.00 34.88  ? 152 ASP A CA  1 
ATOM   1096  C  C   . ASP A 1 152 ? 17.536  24.341  24.812  1.00 30.56  ? 152 ASP A C   1 
ATOM   1097  O  O   . ASP A 1 152 ? 17.186  23.176  24.657  1.00 28.45  ? 152 ASP A O   1 
ATOM   1098  C  CB  . ASP A 1 152 ? 16.945  25.208  22.474  1.00 37.68  ? 152 ASP A CB  1 
ATOM   1099  C  CG  . ASP A 1 152 ? 15.645  25.974  22.717  1.00 39.89  ? 152 ASP A CG  1 
ATOM   1100  O  OD1 . ASP A 1 152 ? 15.127  25.861  23.871  1.00 35.38  ? 152 ASP A OD1 1 
ATOM   1101  O  OD2 . ASP A 1 152 ? 15.128  26.641  21.736  1.00 35.64  ? 152 ASP A OD2 1 
ATOM   1102  N  N   . GLY A 1 153 ? 17.545  24.943  25.994  1.00 30.86  ? 153 GLY A N   1 
ATOM   1103  C  CA  . GLY A 1 153 ? 17.199  24.242  27.223  1.00 29.40  ? 153 GLY A CA  1 
ATOM   1104  C  C   . GLY A 1 153 ? 18.210  24.457  28.365  1.00 25.94  ? 153 GLY A C   1 
ATOM   1105  O  O   . GLY A 1 153 ? 17.893  24.129  29.484  1.00 25.45  ? 153 GLY A O   1 
ATOM   1106  N  N   . THR A 1 154 ? 19.387  25.041  28.102  1.00 25.30  ? 154 THR A N   1 
ATOM   1107  C  CA  . THR A 1 154 ? 20.576  24.912  28.939  1.00 22.34  ? 154 THR A CA  1 
ATOM   1108  C  C   . THR A 1 154 ? 20.354  25.489  30.324  1.00 23.15  ? 154 THR A C   1 
ATOM   1109  O  O   . THR A 1 154 ? 20.742  24.903  31.323  1.00 21.17  ? 154 THR A O   1 
ATOM   1110  C  CB  . THR A 1 154 ? 21.710  25.671  28.271  1.00 25.14  ? 154 THR A CB  1 
ATOM   1111  O  OG1 . THR A 1 154 ? 21.797  25.182  26.926  1.00 25.76  ? 154 THR A OG1 1 
ATOM   1112  C  CG2 . THR A 1 154 ? 23.018  25.536  29.044  1.00 24.69  ? 154 THR A CG2 1 
ATOM   1113  N  N   . GLU A 1 155 ? 19.751  26.677  30.375  1.00 27.02  ? 155 GLU A N   1 
ATOM   1114  C  CA  . GLU A 1 155 ? 19.520  27.367  31.639  1.00 26.46  ? 155 GLU A CA  1 
ATOM   1115  C  C   . GLU A 1 155 ? 18.169  27.036  32.273  1.00 21.33  ? 155 GLU A C   1 
ATOM   1116  O  O   . GLU A 1 155 ? 17.773  27.694  33.210  1.00 20.61  ? 155 GLU A O   1 
ATOM   1117  C  CB  . GLU A 1 155 ? 19.714  28.876  31.446  1.00 31.30  ? 155 GLU A CB  1 
ATOM   1118  C  CG  . GLU A 1 155 ? 21.198  29.258  31.340  1.00 32.52  ? 155 GLU A CG  1 
ATOM   1119  C  CD  . GLU A 1 155 ? 21.943  28.963  32.625  1.00 32.25  ? 155 GLU A CD  1 
ATOM   1120  O  OE1 . GLU A 1 155 ? 21.481  29.512  33.644  1.00 39.66  ? 155 GLU A OE1 1 
ATOM   1121  O  OE2 . GLU A 1 155 ? 22.842  28.129  32.614  1.00 29.79  ? 155 GLU A OE2 1 
ATOM   1122  N  N   . ASN A 1 156 ? 17.473  25.982  31.864  1.00 21.19  ? 156 ASN A N   1 
ATOM   1123  C  CA  . ASN A 1 156 ? 16.285  25.591  32.586  1.00 22.82  ? 156 ASN A CA  1 
ATOM   1124  C  C   . ASN A 1 156 ? 16.626  25.211  34.017  1.00 25.92  ? 156 ASN A C   1 
ATOM   1125  O  O   . ASN A 1 156 ? 17.642  24.577  34.250  1.00 26.51  ? 156 ASN A O   1 
ATOM   1126  C  CB  . ASN A 1 156 ? 15.603  24.363  32.011  1.00 24.71  ? 156 ASN A CB  1 
ATOM   1127  C  CG  . ASN A 1 156 ? 14.573  24.716  30.980  1.00 26.77  ? 156 ASN A CG  1 
ATOM   1128  O  OD1 . ASN A 1 156 ? 13.857  25.727  31.118  1.00 31.49  ? 156 ASN A OD1 1 
ATOM   1129  N  ND2 . ASN A 1 156 ? 14.491  23.886  29.958  1.00 24.81  ? 156 ASN A ND2 1 
ATOM   1130  N  N   . PRO A 1 157 ? 15.759  25.518  35.005  1.00 27.70  ? 157 PRO A N   1 
ATOM   1131  C  CA  . PRO A 1 157 ? 15.989  25.063  36.370  1.00 29.22  ? 157 PRO A CA  1 
ATOM   1132  C  C   . PRO A 1 157 ? 15.883  23.554  36.474  1.00 26.43  ? 157 PRO A C   1 
ATOM   1133  O  O   . PRO A 1 157 ? 15.286  22.948  35.590  1.00 26.14  ? 157 PRO A O   1 
ATOM   1134  C  CB  . PRO A 1 157 ? 14.877  25.814  37.111  1.00 31.74  ? 157 PRO A CB  1 
ATOM   1135  C  CG  . PRO A 1 157 ? 13.763  25.930  36.106  1.00 30.58  ? 157 PRO A CG  1 
ATOM   1136  C  CD  . PRO A 1 157 ? 14.541  26.318  34.879  1.00 28.75  ? 157 PRO A CD  1 
ATOM   1137  N  N   . THR A 1 158 ? 16.526  22.973  37.499  1.00 29.20  ? 158 THR A N   1 
ATOM   1138  C  CA  . THR A 1 158 ? 16.421  21.535  37.740  1.00 34.39  ? 158 THR A CA  1 
ATOM   1139  C  C   . THR A 1 158 ? 16.168  21.246  39.220  1.00 34.62  ? 158 THR A C   1 
ATOM   1140  O  O   . THR A 1 158 ? 16.385  22.093  40.099  1.00 32.33  ? 158 THR A O   1 
ATOM   1141  C  CB  . THR A 1 158 ? 17.644  20.755  37.246  1.00 30.51  ? 158 THR A CB  1 
ATOM   1142  O  OG1 . THR A 1 158 ? 18.683  21.381  37.970  1.00 25.94  ? 158 THR A OG1 1 
ATOM   1143  C  CG2 . THR A 1 158 ? 17.843  20.838  35.741  1.00 35.56  ? 158 THR A CG2 1 
ATOM   1144  N  N   . GLY A 1 159 ? 15.681  20.015  39.445  1.00 35.35  ? 159 GLY A N   1 
ATOM   1145  C  CA  . GLY A 1 159 ? 15.384  19.489  40.763  1.00 34.43  ? 159 GLY A CA  1 
ATOM   1146  C  C   . GLY A 1 159 ? 14.492  20.426  41.555  1.00 36.38  ? 159 GLY A C   1 
ATOM   1147  O  O   . GLY A 1 159 ? 13.433  20.771  41.083  1.00 36.47  ? 159 GLY A O   1 
ATOM   1148  N  N   . ALA A 1 160 ? 14.941  20.821  42.756  1.00 40.29  ? 160 ALA A N   1 
ATOM   1149  C  CA  . ALA A 1 160 ? 14.104  21.508  43.717  1.00 37.79  ? 160 ALA A CA  1 
ATOM   1150  C  C   . ALA A 1 160 ? 13.839  22.912  43.206  1.00 35.30  ? 160 ALA A C   1 
ATOM   1151  O  O   . ALA A 1 160 ? 12.752  23.432  43.426  1.00 36.19  ? 160 ALA A O   1 
ATOM   1152  C  CB  . ALA A 1 160 ? 14.735  21.507  45.095  1.00 37.12  ? 160 ALA A CB  1 
ATOM   1153  N  N   . ALA A 1 161 ? 14.810  23.510  42.505  1.00 34.96  ? 161 ALA A N   1 
ATOM   1154  C  CA  . ALA A 1 161 ? 14.618  24.868  41.989  1.00 36.40  ? 161 ALA A CA  1 
ATOM   1155  C  C   . ALA A 1 161 ? 13.462  24.880  40.981  1.00 35.27  ? 161 ALA A C   1 
ATOM   1156  O  O   . ALA A 1 161 ? 12.654  25.813  40.967  1.00 31.96  ? 161 ALA A O   1 
ATOM   1157  C  CB  . ALA A 1 161 ? 15.893  25.411  41.387  1.00 34.17  ? 161 ALA A CB  1 
ATOM   1158  N  N   . ALA A 1 162 ? 13.363  23.807  40.195  1.00 31.66  ? 162 ALA A N   1 
ATOM   1159  C  CA  . ALA A 1 162 ? 12.313  23.674  39.205  1.00 33.45  ? 162 ALA A CA  1 
ATOM   1160  C  C   . ALA A 1 162 ? 10.947  23.477  39.874  1.00 35.87  ? 162 ALA A C   1 
ATOM   1161  O  O   . ALA A 1 162 ? 9.991   24.170  39.502  1.00 33.96  ? 162 ALA A O   1 
ATOM   1162  C  CB  . ALA A 1 162 ? 12.676  22.547  38.249  1.00 31.13  ? 162 ALA A CB  1 
ATOM   1163  N  N   . ARG A 1 163 ? 10.876  22.562  40.867  1.00 34.42  ? 163 ARG A N   1 
ATOM   1164  C  CA  . ARG A 1 163 ? 9.669   22.327  41.651  1.00 36.23  ? 163 ARG A CA  1 
ATOM   1165  C  C   . ARG A 1 163 ? 9.209   23.689  42.164  1.00 35.11  ? 163 ARG A C   1 
ATOM   1166  O  O   . ARG A 1 163 ? 8.065   24.038  41.940  1.00 32.97  ? 163 ARG A O   1 
ATOM   1167  C  CB  . ARG A 1 163 ? 9.818   21.289  42.776  1.00 48.99  ? 163 ARG A CB  1 
ATOM   1168  C  CG  . ARG A 1 163 ? 10.871  20.190  42.564  1.00 73.40  ? 163 ARG A CG  1 
ATOM   1169  C  CD  . ARG A 1 163 ? 11.254  19.253  43.738  1.00 76.31  ? 163 ARG A CD  1 
ATOM   1170  N  NE  . ARG A 1 163 ? 9.994   18.792  44.322  1.00 88.70  ? 163 ARG A NE  1 
ATOM   1171  C  CZ  . ARG A 1 163 ? 8.966   18.305  43.616  1.00 87.32  ? 163 ARG A CZ  1 
ATOM   1172  N  NH1 . ARG A 1 163 ? 9.144   17.837  42.381  1.00 76.96  ? 163 ARG A NH1 1 
ATOM   1173  N  NH2 . ARG A 1 163 ? 7.764   18.264  44.178  1.00 86.94  ? 163 ARG A NH2 1 
ATOM   1174  N  N   . ARG A 1 164 ? 10.112  24.500  42.748  1.00 30.86  ? 164 ARG A N   1 
ATOM   1175  C  CA  . ARG A 1 164 ? 9.721   25.773  43.328  1.00 34.12  ? 164 ARG A CA  1 
ATOM   1176  C  C   . ARG A 1 164 ? 9.309   26.768  42.258  1.00 28.93  ? 164 ARG A C   1 
ATOM   1177  O  O   . ARG A 1 164 ? 8.509   27.629  42.516  1.00 27.62  ? 164 ARG A O   1 
ATOM   1178  C  CB  . ARG A 1 164 ? 10.754  26.306  44.324  1.00 49.04  ? 164 ARG A CB  1 
ATOM   1179  C  CG  . ARG A 1 164 ? 10.163  26.255  45.734  1.00 64.34  ? 164 ARG A CG  1 
ATOM   1180  C  CD  . ARG A 1 164 ? 11.115  26.775  46.806  1.00 81.43  ? 164 ARG A CD  1 
ATOM   1181  N  NE  . ARG A 1 164 ? 11.960  27.850  46.255  1.00 103.50 ? 164 ARG A NE  1 
ATOM   1182  C  CZ  . ARG A 1 164 ? 13.057  27.724  45.470  1.00 99.51  ? 164 ARG A CZ  1 
ATOM   1183  N  NH1 . ARG A 1 164 ? 13.685  26.559  45.326  1.00 84.74  ? 164 ARG A NH1 1 
ATOM   1184  N  NH2 . ARG A 1 164 ? 13.544  28.793  44.852  1.00 86.99  ? 164 ARG A NH2 1 
ATOM   1185  N  N   . ALA A 1 165 ? 9.818   26.680  41.037  1.00 30.15  ? 165 ALA A N   1 
ATOM   1186  C  CA  . ALA A 1 165 ? 9.493   27.685  40.030  1.00 28.05  ? 165 ALA A CA  1 
ATOM   1187  C  C   . ALA A 1 165 ? 8.166   27.378  39.321  1.00 30.33  ? 165 ALA A C   1 
ATOM   1188  O  O   . ALA A 1 165 ? 7.556   28.305  38.750  1.00 25.59  ? 165 ALA A O   1 
ATOM   1189  C  CB  . ALA A 1 165 ? 10.595  27.778  39.009  1.00 26.31  ? 165 ALA A CB  1 
ATOM   1190  N  N   . VAL A 1 166 ? 7.751   26.097  39.291  1.00 24.78  ? 166 VAL A N   1 
ATOM   1191  C  CA  . VAL A 1 166 ? 6.679   25.753  38.384  1.00 25.89  ? 166 VAL A CA  1 
ATOM   1192  C  C   . VAL A 1 166 ? 5.377   25.369  39.100  1.00 26.05  ? 166 VAL A C   1 
ATOM   1193  O  O   . VAL A 1 166 ? 4.301   25.519  38.507  1.00 23.98  ? 166 VAL A O   1 
ATOM   1194  C  CB  . VAL A 1 166 ? 7.054   24.729  37.301  1.00 29.05  ? 166 VAL A CB  1 
ATOM   1195  C  CG1 . VAL A 1 166 ? 8.439   25.002  36.724  1.00 29.67  ? 166 VAL A CG1 1 
ATOM   1196  C  CG2 . VAL A 1 166 ? 6.906   23.330  37.822  1.00 30.99  ? 166 VAL A CG2 1 
ATOM   1197  N  N   . LEU A 1 167 ? 5.446   24.896  40.353  1.00 23.79  ? 167 LEU A N   1 
ATOM   1198  C  CA  . LEU A 1 167 ? 4.264   24.350  41.010  1.00 24.77  ? 167 LEU A CA  1 
ATOM   1199  C  C   . LEU A 1 167 ? 3.590   25.359  41.949  1.00 28.48  ? 167 LEU A C   1 
ATOM   1200  O  O   . LEU A 1 167 ? 4.220   26.059  42.735  1.00 25.96  ? 167 LEU A O   1 
ATOM   1201  C  CB  . LEU A 1 167 ? 4.644   23.092  41.761  1.00 23.94  ? 167 LEU A CB  1 
ATOM   1202  C  CG  . LEU A 1 167 ? 5.151   21.959  40.876  1.00 27.90  ? 167 LEU A CG  1 
ATOM   1203  C  CD1 . LEU A 1 167 ? 5.570   20.744  41.679  1.00 29.89  ? 167 LEU A CD1 1 
ATOM   1204  C  CD2 . LEU A 1 167 ? 4.057   21.589  39.888  1.00 31.21  ? 167 LEU A CD2 1 
ATOM   1205  N  N   . VAL A 1 168 ? 2.268   25.467  41.801  1.00 32.95  ? 168 VAL A N   1 
ATOM   1206  C  CA  . VAL A 1 168 ? 1.468   26.311  42.658  1.00 34.33  ? 168 VAL A CA  1 
ATOM   1207  C  C   . VAL A 1 168 ? 1.599   25.761  44.083  1.00 36.19  ? 168 VAL A C   1 
ATOM   1208  O  O   . VAL A 1 168 ? 1.561   24.545  44.292  1.00 26.13  ? 168 VAL A O   1 
ATOM   1209  C  CB  . VAL A 1 168 ? 0.012   26.302  42.159  1.00 35.85  ? 168 VAL A CB  1 
ATOM   1210  C  CG1 . VAL A 1 168 ? -0.923  26.951  43.159  1.00 38.57  ? 168 VAL A CG1 1 
ATOM   1211  C  CG2 . VAL A 1 168 ? -0.124  26.966  40.796  1.00 35.37  ? 168 VAL A CG2 1 
ATOM   1212  N  N   . GLY A 1 169 ? 1.760   26.662  45.060  1.00 33.73  ? 169 GLY A N   1 
ATOM   1213  C  CA  . GLY A 1 169 ? 1.852   26.236  46.444  1.00 33.27  ? 169 GLY A CA  1 
ATOM   1214  C  C   . GLY A 1 169 ? 0.838   26.932  47.341  1.00 35.32  ? 169 GLY A C   1 
ATOM   1215  O  O   . GLY A 1 169 ? -0.328  27.059  46.980  1.00 35.81  ? 169 GLY A O   1 
ATOM   1216  N  N   . ALA A 1 170 ? 1.332   27.351  48.517  1.00 33.66  ? 170 ALA A N   1 
ATOM   1217  C  CA  . ALA A 1 170 ? 0.629   28.089  49.556  1.00 35.20  ? 170 ALA A CA  1 
ATOM   1218  C  C   . ALA A 1 170 ? -0.156  29.312  49.072  1.00 32.74  ? 170 ALA A C   1 
ATOM   1219  O  O   . ALA A 1 170 ? -1.163  29.666  49.653  1.00 32.25  ? 170 ALA A O   1 
ATOM   1220  C  CB  . ALA A 1 170 ? 1.676   28.598  50.523  1.00 35.58  ? 170 ALA A CB  1 
ATOM   1221  N  N   . GLU A 1 171 ? 0.324   29.983  48.029  1.00 31.35  ? 171 GLU A N   1 
ATOM   1222  C  CA  . GLU A 1 171 ? -0.266  31.233  47.577  1.00 28.81  ? 171 GLU A CA  1 
ATOM   1223  C  C   . GLU A 1 171 ? -1.630  31.009  46.923  1.00 26.72  ? 171 GLU A C   1 
ATOM   1224  O  O   . GLU A 1 171 ? -2.327  31.982  46.643  1.00 26.42  ? 171 GLU A O   1 
ATOM   1225  C  CB  . GLU A 1 171 ? 0.708   32.002  46.668  1.00 30.96  ? 171 GLU A CB  1 
ATOM   1226  C  CG  . GLU A 1 171 ? 0.836   31.512  45.224  1.00 31.28  ? 171 GLU A CG  1 
ATOM   1227  C  CD  . GLU A 1 171 ? 1.556   30.193  44.963  1.00 35.07  ? 171 GLU A CD  1 
ATOM   1228  O  OE1 . GLU A 1 171 ? 2.069   29.543  45.907  1.00 28.79  ? 171 GLU A OE1 1 
ATOM   1229  O  OE2 . GLU A 1 171 ? 1.600   29.816  43.780  1.00 38.37  ? 171 GLU A OE2 1 
ATOM   1230  N  N   . ASP A 1 172 ? -1.999  29.756  46.618  1.00 25.13  ? 172 ASP A N   1 
ATOM   1231  C  CA  . ASP A 1 172 ? -3.307  29.441  46.055  1.00 25.21  ? 172 ASP A CA  1 
ATOM   1232  C  C   . ASP A 1 172 ? -3.607  27.995  46.428  1.00 25.84  ? 172 ASP A C   1 
ATOM   1233  O  O   . ASP A 1 172 ? -3.640  27.101  45.586  1.00 24.71  ? 172 ASP A O   1 
ATOM   1234  C  CB  . ASP A 1 172 ? -3.362  29.694  44.549  1.00 28.38  ? 172 ASP A CB  1 
ATOM   1235  C  CG  . ASP A 1 172 ? -4.716  29.559  43.860  1.00 28.12  ? 172 ASP A CG  1 
ATOM   1236  O  OD1 . ASP A 1 172 ? -5.688  29.526  44.605  1.00 30.60  ? 172 ASP A OD1 1 
ATOM   1237  O  OD2 . ASP A 1 172 ? -4.795  29.587  42.601  1.00 27.16  ? 172 ASP A OD2 1 
ATOM   1238  N  N   . PRO A 1 173 ? -3.846  27.727  47.725  1.00 30.74  ? 173 PRO A N   1 
ATOM   1239  C  CA  . PRO A 1 173 ? -3.770  26.362  48.277  1.00 29.75  ? 173 PRO A CA  1 
ATOM   1240  C  C   . PRO A 1 173 ? -4.780  25.359  47.729  1.00 26.27  ? 173 PRO A C   1 
ATOM   1241  O  O   . PRO A 1 173 ? -4.537  24.152  47.711  1.00 26.96  ? 173 PRO A O   1 
ATOM   1242  C  CB  . PRO A 1 173 ? -3.988  26.533  49.793  1.00 28.98  ? 173 PRO A CB  1 
ATOM   1243  C  CG  . PRO A 1 173 ? -4.546  27.925  49.952  1.00 28.86  ? 173 PRO A CG  1 
ATOM   1244  C  CD  . PRO A 1 173 ? -4.189  28.743  48.728  1.00 31.35  ? 173 PRO A CD  1 
ATOM   1245  N  N   . ALA A 1 174 ? -5.916  25.882  47.271  1.00 24.59  ? 174 ALA A N   1 
ATOM   1246  C  CA  . ALA A 1 174 ? -6.912  25.036  46.657  1.00 25.11  ? 174 ALA A CA  1 
ATOM   1247  C  C   . ALA A 1 174 ? -6.385  24.378  45.398  1.00 25.49  ? 174 ALA A C   1 
ATOM   1248  O  O   . ALA A 1 174 ? -6.993  23.405  45.012  1.00 29.67  ? 174 ALA A O   1 
ATOM   1249  C  CB  . ALA A 1 174 ? -8.135  25.824  46.325  1.00 27.10  ? 174 ALA A CB  1 
ATOM   1250  N  N   . PHE A 1 175 ? -5.351  24.939  44.745  1.00 28.60  ? 175 PHE A N   1 
ATOM   1251  C  CA  . PHE A 1 175 ? -4.869  24.480  43.437  1.00 30.43  ? 175 PHE A CA  1 
ATOM   1252  C  C   . PHE A 1 175 ? -3.391  24.071  43.437  1.00 29.97  ? 175 PHE A C   1 
ATOM   1253  O  O   . PHE A 1 175 ? -2.786  23.885  42.375  1.00 28.04  ? 175 PHE A O   1 
ATOM   1254  C  CB  . PHE A 1 175 ? -5.136  25.629  42.452  1.00 28.17  ? 175 PHE A CB  1 
ATOM   1255  C  CG  . PHE A 1 175 ? -6.631  25.789  42.213  1.00 26.76  ? 175 PHE A CG  1 
ATOM   1256  C  CD1 . PHE A 1 175 ? -7.346  24.803  41.536  1.00 26.77  ? 175 PHE A CD1 1 
ATOM   1257  C  CD2 . PHE A 1 175 ? -7.333  26.857  42.743  1.00 27.77  ? 175 PHE A CD2 1 
ATOM   1258  C  CE1 . PHE A 1 175 ? -8.712  24.893  41.364  1.00 27.71  ? 175 PHE A CE1 1 
ATOM   1259  C  CE2 . PHE A 1 175 ? -8.702  26.955  42.577  1.00 29.76  ? 175 PHE A CE2 1 
ATOM   1260  C  CZ  . PHE A 1 175 ? -9.397  25.958  41.919  1.00 28.91  ? 175 PHE A CZ  1 
ATOM   1261  N  N   . ALA A 1 176 ? -2.820  23.955  44.641  1.00 31.16  ? 176 ALA A N   1 
ATOM   1262  C  CA  . ALA A 1 176 ? -1.469  23.466  44.844  1.00 31.17  ? 176 ALA A CA  1 
ATOM   1263  C  C   . ALA A 1 176 ? -1.246  22.178  44.043  1.00 29.04  ? 176 ALA A C   1 
ATOM   1264  O  O   . ALA A 1 176 ? -2.070  21.268  44.104  1.00 27.73  ? 176 ALA A O   1 
ATOM   1265  C  CB  . ALA A 1 176 ? -1.252  23.242  46.324  1.00 29.72  ? 176 ALA A CB  1 
ATOM   1266  N  N   . GLY A 1 177 ? -0.115  22.136  43.306  1.00 27.15  ? 177 GLY A N   1 
ATOM   1267  C  CA  . GLY A 1 177 ? 0.271   20.982  42.500  1.00 24.92  ? 177 GLY A CA  1 
ATOM   1268  C  C   . GLY A 1 177 ? 0.087   21.266  41.017  1.00 25.96  ? 177 GLY A C   1 
ATOM   1269  O  O   . GLY A 1 177 ? 0.483   20.491  40.115  1.00 33.04  ? 177 GLY A O   1 
ATOM   1270  N  N   . GLY A 1 178 ? -0.574  22.397  40.786  1.00 24.24  ? 178 GLY A N   1 
ATOM   1271  C  CA  . GLY A 1 178 ? -0.849  22.842  39.432  1.00 23.98  ? 178 GLY A CA  1 
ATOM   1272  C  C   . GLY A 1 178 ? 0.287   23.706  38.916  1.00 22.43  ? 178 GLY A C   1 
ATOM   1273  O  O   . GLY A 1 178 ? 1.270   23.962  39.619  1.00 20.29  ? 178 GLY A O   1 
ATOM   1274  N  N   . SER A 1 179 ? 0.105   24.128  37.664  1.00 24.27  ? 179 SER A N   1 
ATOM   1275  C  CA  . SER A 1 179 ? 1.043   25.001  37.000  1.00 20.86  ? 179 SER A CA  1 
ATOM   1276  C  C   . SER A 1 179 ? 0.309   25.724  35.890  1.00 19.29  ? 179 SER A C   1 
ATOM   1277  O  O   . SER A 1 179 ? -0.825  25.392  35.567  1.00 17.82  ? 179 SER A O   1 
ATOM   1278  C  CB  . SER A 1 179 ? 2.243   24.218  36.495  1.00 20.85  ? 179 SER A CB  1 
ATOM   1279  O  OG  . SER A 1 179 ? 3.316   25.080  36.128  1.00 18.47  ? 179 SER A OG  1 
ATOM   1280  N  N   . TYR A 1 180 ? 0.989   26.728  35.344  1.00 20.59  ? 180 TYR A N   1 
ATOM   1281  C  CA  . TYR A 1 180 ? 0.479   27.521  34.241  1.00 21.45  ? 180 TYR A CA  1 
ATOM   1282  C  C   . TYR A 1 180 ? 1.387   27.288  33.042  1.00 20.43  ? 180 TYR A C   1 
ATOM   1283  O  O   . TYR A 1 180 ? 2.575   27.550  33.108  1.00 21.82  ? 180 TYR A O   1 
ATOM   1284  C  CB  . TYR A 1 180 ? 0.370   29.012  34.609  1.00 21.16  ? 180 TYR A CB  1 
ATOM   1285  C  CG  . TYR A 1 180 ? -0.636  29.307  35.722  1.00 25.00  ? 180 TYR A CG  1 
ATOM   1286  C  CD1 . TYR A 1 180 ? -0.286  29.221  37.074  1.00 25.80  ? 180 TYR A CD1 1 
ATOM   1287  C  CD2 . TYR A 1 180 ? -1.966  29.632  35.436  1.00 27.19  ? 180 TYR A CD2 1 
ATOM   1288  C  CE1 . TYR A 1 180 ? -1.206  29.470  38.085  1.00 25.42  ? 180 TYR A CE1 1 
ATOM   1289  C  CE2 . TYR A 1 180 ? -2.893  29.893  36.445  1.00 29.18  ? 180 TYR A CE2 1 
ATOM   1290  C  CZ  . TYR A 1 180 ? -2.511  29.822  37.770  1.00 27.35  ? 180 TYR A CZ  1 
ATOM   1291  O  OH  . TYR A 1 180 ? -3.428  30.088  38.730  1.00 24.86  ? 180 TYR A OH  1 
ATOM   1292  N  N   . ALA A 1 181 ? 0.775   26.883  31.928  1.00 20.97  ? 181 ALA A N   1 
ATOM   1293  C  CA  . ALA A 1 181 ? 1.487   26.684  30.675  1.00 21.16  ? 181 ALA A CA  1 
ATOM   1294  C  C   . ALA A 1 181 ? 1.092   27.765  29.676  1.00 22.60  ? 181 ALA A C   1 
ATOM   1295  O  O   . ALA A 1 181 ? -0.100  27.982  29.433  1.00 23.61  ? 181 ALA A O   1 
ATOM   1296  C  CB  . ALA A 1 181 ? 1.154   25.332  30.103  1.00 19.86  ? 181 ALA A CB  1 
ATOM   1297  N  N   . VAL A 1 182 ? 2.109   28.424  29.104  1.00 21.56  ? 182 VAL A N   1 
ATOM   1298  C  CA  . VAL A 1 182 ? 1.932   29.276  27.943  1.00 23.14  ? 182 VAL A CA  1 
ATOM   1299  C  C   . VAL A 1 182 ? 2.527   28.572  26.719  1.00 22.15  ? 182 VAL A C   1 
ATOM   1300  O  O   . VAL A 1 182 ? 3.645   28.092  26.785  1.00 18.14  ? 182 VAL A O   1 
ATOM   1301  C  CB  . VAL A 1 182 ? 2.613   30.620  28.210  1.00 23.80  ? 182 VAL A CB  1 
ATOM   1302  C  CG1 . VAL A 1 182 ? 2.514   31.511  26.995  1.00 25.46  ? 182 VAL A CG1 1 
ATOM   1303  C  CG2 . VAL A 1 182 ? 2.031   31.284  29.452  1.00 24.46  ? 182 VAL A CG2 1 
ATOM   1304  N  N   . VAL A 1 183 ? 1.771   28.543  25.616  1.00 23.46  ? 183 VAL A N   1 
ATOM   1305  C  CA  . VAL A 1 183 ? 2.228   27.991  24.345  1.00 24.65  ? 183 VAL A CA  1 
ATOM   1306  C  C   . VAL A 1 183 ? 2.213   29.106  23.295  1.00 24.84  ? 183 VAL A C   1 
ATOM   1307  O  O   . VAL A 1 183 ? 1.341   29.972  23.304  1.00 23.62  ? 183 VAL A O   1 
ATOM   1308  C  CB  . VAL A 1 183 ? 1.443   26.763  23.844  1.00 26.35  ? 183 VAL A CB  1 
ATOM   1309  C  CG1 . VAL A 1 183 ? 1.487   25.615  24.853  1.00 30.44  ? 183 VAL A CG1 1 
ATOM   1310  C  CG2 . VAL A 1 183 ? 0.001   27.089  23.551  1.00 25.59  ? 183 VAL A CG2 1 
ATOM   1311  N  N   . GLN A 1 184 ? 3.232   29.092  22.440  1.00 21.61  ? 184 GLN A N   1 
ATOM   1312  C  CA  . GLN A 1 184 ? 3.275   29.894  21.232  1.00 22.10  ? 184 GLN A CA  1 
ATOM   1313  C  C   . GLN A 1 184 ? 3.970   29.095  20.125  1.00 22.55  ? 184 GLN A C   1 
ATOM   1314  O  O   . GLN A 1 184 ? 5.062   28.558  20.304  1.00 22.76  ? 184 GLN A O   1 
ATOM   1315  C  CB  . GLN A 1 184 ? 4.086   31.165  21.423  1.00 19.95  ? 184 GLN A CB  1 
ATOM   1316  C  CG  . GLN A 1 184 ? 3.493   32.164  22.408  1.00 20.92  ? 184 GLN A CG  1 
ATOM   1317  C  CD  . GLN A 1 184 ? 4.341   33.394  22.456  1.00 22.34  ? 184 GLN A CD  1 
ATOM   1318  O  OE1 . GLN A 1 184 ? 5.471   33.295  22.941  1.00 21.08  ? 184 GLN A OE1 1 
ATOM   1319  N  NE2 . GLN A 1 184 ? 3.845   34.477  21.848  1.00 24.97  ? 184 GLN A NE2 1 
ATOM   1320  N  N   . LYS A 1 185 ? 3.334   28.994  18.966  1.00 21.93  ? 185 LYS A N   1 
ATOM   1321  C  CA  . LYS A 1 185 ? 3.984   28.399  17.829  1.00 21.32  ? 185 LYS A CA  1 
ATOM   1322  C  C   . LYS A 1 185 ? 4.687   29.505  17.057  1.00 20.17  ? 185 LYS A C   1 
ATOM   1323  O  O   . LYS A 1 185 ? 4.033   30.455  16.639  1.00 21.22  ? 185 LYS A O   1 
ATOM   1324  C  CB  . LYS A 1 185 ? 2.938   27.688  16.980  1.00 23.52  ? 185 LYS A CB  1 
ATOM   1325  C  CG  . LYS A 1 185 ? 3.547   27.186  15.660  1.00 25.55  ? 185 LYS A CG  1 
ATOM   1326  C  CD  . LYS A 1 185 ? 2.808   26.029  15.037  1.00 28.58  ? 185 LYS A CD  1 
ATOM   1327  C  CE  . LYS A 1 185 ? 1.539   26.482  14.479  1.00 32.53  ? 185 LYS A CE  1 
ATOM   1328  N  NZ  . LYS A 1 185 ? 0.778   25.392  13.867  1.00 37.03  ? 185 LYS A NZ  1 
ATOM   1329  N  N   . TYR A 1 186 ? 6.011   29.369  16.874  1.00 19.73  ? 186 TYR A N   1 
ATOM   1330  C  CA  . TYR A 1 186 ? 6.810   30.336  16.126  1.00 20.28  ? 186 TYR A CA  1 
ATOM   1331  C  C   . TYR A 1 186 ? 7.265   29.746  14.800  1.00 19.66  ? 186 TYR A C   1 
ATOM   1332  O  O   . TYR A 1 186 ? 7.662   28.594  14.744  1.00 20.77  ? 186 TYR A O   1 
ATOM   1333  C  CB  . TYR A 1 186 ? 8.071   30.751  16.879  1.00 18.71  ? 186 TYR A CB  1 
ATOM   1334  C  CG  . TYR A 1 186 ? 7.826   31.736  18.004  1.00 18.93  ? 186 TYR A CG  1 
ATOM   1335  C  CD1 . TYR A 1 186 ? 7.827   33.100  17.780  1.00 17.66  ? 186 TYR A CD1 1 
ATOM   1336  C  CD2 . TYR A 1 186 ? 7.600   31.277  19.295  1.00 20.17  ? 186 TYR A CD2 1 
ATOM   1337  C  CE1 . TYR A 1 186 ? 7.627   33.993  18.821  1.00 18.49  ? 186 TYR A CE1 1 
ATOM   1338  C  CE2 . TYR A 1 186 ? 7.339   32.147  20.338  1.00 22.43  ? 186 TYR A CE2 1 
ATOM   1339  C  CZ  . TYR A 1 186 ? 7.368   33.519  20.105  1.00 22.05  ? 186 TYR A CZ  1 
ATOM   1340  O  OH  . TYR A 1 186 ? 7.181   34.361  21.161  1.00 19.67  ? 186 TYR A OH  1 
ATOM   1341  N  N   . LEU A 1 187 ? 7.233   30.580  13.751  1.00 21.94  ? 187 LEU A N   1 
ATOM   1342  C  CA  . LEU A 1 187 ? 7.871   30.248  12.492  1.00 19.05  ? 187 LEU A CA  1 
ATOM   1343  C  C   . LEU A 1 187 ? 9.083   31.143  12.323  1.00 18.80  ? 187 LEU A C   1 
ATOM   1344  O  O   . LEU A 1 187 ? 9.041   32.305  12.656  1.00 21.05  ? 187 LEU A O   1 
ATOM   1345  C  CB  . LEU A 1 187 ? 6.890   30.433  11.343  1.00 19.29  ? 187 LEU A CB  1 
ATOM   1346  C  CG  . LEU A 1 187 ? 5.689   29.495  11.365  1.00 21.85  ? 187 LEU A CG  1 
ATOM   1347  C  CD1 . LEU A 1 187 ? 4.766   29.907  10.256  1.00 20.52  ? 187 LEU A CD1 1 
ATOM   1348  C  CD2 . LEU A 1 187 ? 6.090   28.042  11.229  1.00 22.71  ? 187 LEU A CD2 1 
ATOM   1349  N  N   . HIS A 1 188 ? 10.154  30.594  11.776  1.00 17.41  ? 188 HIS A N   1 
ATOM   1350  C  CA  . HIS A 1 188 ? 11.371  31.352  11.611  1.00 19.49  ? 188 HIS A CA  1 
ATOM   1351  C  C   . HIS A 1 188 ? 11.577  31.652  10.136  1.00 20.07  ? 188 HIS A C   1 
ATOM   1352  O  O   . HIS A 1 188 ? 11.203  30.849  9.291   1.00 20.72  ? 188 HIS A O   1 
ATOM   1353  C  CB  . HIS A 1 188 ? 12.570  30.573  12.132  1.00 19.19  ? 188 HIS A CB  1 
ATOM   1354  C  CG  . HIS A 1 188 ? 12.475  30.238  13.579  1.00 17.81  ? 188 HIS A CG  1 
ATOM   1355  N  ND1 . HIS A 1 188 ? 12.612  31.214  14.531  1.00 17.67  ? 188 HIS A ND1 1 
ATOM   1356  C  CD2 . HIS A 1 188 ? 12.268  29.072  14.229  1.00 18.13  ? 188 HIS A CD2 1 
ATOM   1357  C  CE1 . HIS A 1 188 ? 12.525  30.638  15.727  1.00 17.31  ? 188 HIS A CE1 1 
ATOM   1358  N  NE2 . HIS A 1 188 ? 12.296  29.340  15.571  1.00 17.21  ? 188 HIS A NE2 1 
ATOM   1359  N  N   . ASP A 1 189 ? 12.088  32.849  9.858   1.00 20.78  ? 189 ASP A N   1 
ATOM   1360  C  CA  . ASP A 1 189 ? 12.545  33.257  8.546   1.00 20.73  ? 189 ASP A CA  1 
ATOM   1361  C  C   . ASP A 1 189 ? 14.017  32.851  8.464   1.00 20.07  ? 189 ASP A C   1 
ATOM   1362  O  O   . ASP A 1 189 ? 14.921  33.607  8.816   1.00 20.89  ? 189 ASP A O   1 
ATOM   1363  C  CB  . ASP A 1 189 ? 12.385  34.753  8.343   1.00 21.62  ? 189 ASP A CB  1 
ATOM   1364  C  CG  . ASP A 1 189 ? 12.811  35.250  6.962   1.00 25.87  ? 189 ASP A CG  1 
ATOM   1365  O  OD1 . ASP A 1 189 ? 13.407  34.446  6.184   1.00 25.22  ? 189 ASP A OD1 1 
ATOM   1366  O  OD2 . ASP A 1 189 ? 12.457  36.410  6.615   1.00 25.85  ? 189 ASP A OD2 1 
ATOM   1367  N  N   . ILE A 1 190 ? 14.222  31.618  8.031   1.00 19.21  ? 190 ILE A N   1 
ATOM   1368  C  CA  . ILE A 1 190 ? 15.532  31.009  8.054   1.00 20.88  ? 190 ILE A CA  1 
ATOM   1369  C  C   . ILE A 1 190 ? 16.463  31.690  7.070   1.00 19.72  ? 190 ILE A C   1 
ATOM   1370  O  O   . ILE A 1 190 ? 17.659  31.754  7.313   1.00 22.25  ? 190 ILE A O   1 
ATOM   1371  C  CB  . ILE A 1 190 ? 15.422  29.503  7.764   1.00 23.34  ? 190 ILE A CB  1 
ATOM   1372  C  CG1 . ILE A 1 190 ? 14.804  28.737  8.946   1.00 22.85  ? 190 ILE A CG1 1 
ATOM   1373  C  CG2 . ILE A 1 190 ? 16.798  28.965  7.400   1.00 25.40  ? 190 ILE A CG2 1 
ATOM   1374  C  CD1 . ILE A 1 190 ? 15.625  28.782  10.223  1.00 21.33  ? 190 ILE A CD1 1 
ATOM   1375  N  N   . ASP A 1 191 ? 15.936  32.162  5.939   1.00 21.00  ? 191 ASP A N   1 
ATOM   1376  C  CA  . ASP A 1 191 ? 16.759  32.796  4.923   1.00 21.12  ? 191 ASP A CA  1 
ATOM   1377  C  C   . ASP A 1 191 ? 17.442  34.019  5.520   1.00 17.75  ? 191 ASP A C   1 
ATOM   1378  O  O   . ASP A 1 191 ? 18.649  34.210  5.392   1.00 17.55  ? 191 ASP A O   1 
ATOM   1379  C  CB  . ASP A 1 191 ? 15.944  33.100  3.672   1.00 21.08  ? 191 ASP A CB  1 
ATOM   1380  C  CG  . ASP A 1 191 ? 15.524  31.871  2.888   1.00 20.64  ? 191 ASP A CG  1 
ATOM   1381  O  OD1 . ASP A 1 191 ? 16.375  31.054  2.701   1.00 21.71  ? 191 ASP A OD1 1 
ATOM   1382  O  OD2 . ASP A 1 191 ? 14.333  31.703  2.493   1.00 23.45  ? 191 ASP A OD2 1 
ATOM   1383  N  N   . ALA A 1 192 ? 16.647  34.844  6.180   1.00 18.01  ? 192 ALA A N   1 
ATOM   1384  C  CA  . ALA A 1 192 ? 17.184  36.025  6.818   1.00 19.61  ? 192 ALA A CA  1 
ATOM   1385  C  C   . ALA A 1 192 ? 18.248  35.646  7.847   1.00 21.71  ? 192 ALA A C   1 
ATOM   1386  O  O   . ALA A 1 192 ? 19.294  36.279  7.956   1.00 23.43  ? 192 ALA A O   1 
ATOM   1387  C  CB  . ALA A 1 192 ? 16.046  36.778  7.468   1.00 20.50  ? 192 ALA A CB  1 
ATOM   1388  N  N   . TRP A 1 193 ? 17.927  34.632  8.661   1.00 24.30  ? 193 TRP A N   1 
ATOM   1389  C  CA  . TRP A 1 193 ? 18.764  34.220  9.773   1.00 23.07  ? 193 TRP A CA  1 
ATOM   1390  C  C   . TRP A 1 193 ? 20.138  33.782  9.284   1.00 26.64  ? 193 TRP A C   1 
ATOM   1391  O  O   . TRP A 1 193 ? 21.161  34.168  9.832   1.00 31.70  ? 193 TRP A O   1 
ATOM   1392  C  CB  . TRP A 1 193 ? 18.056  33.098  10.539  1.00 21.01  ? 193 TRP A CB  1 
ATOM   1393  C  CG  . TRP A 1 193 ? 18.832  32.551  11.700  1.00 19.50  ? 193 TRP A CG  1 
ATOM   1394  C  CD1 . TRP A 1 193 ? 19.344  31.301  11.835  1.00 20.34  ? 193 TRP A CD1 1 
ATOM   1395  C  CD2 . TRP A 1 193 ? 19.159  33.246  12.912  1.00 21.08  ? 193 TRP A CD2 1 
ATOM   1396  N  NE1 . TRP A 1 193 ? 19.942  31.147  13.052  1.00 21.66  ? 193 TRP A NE1 1 
ATOM   1397  C  CE2 . TRP A 1 193 ? 19.857  32.329  13.735  1.00 22.26  ? 193 TRP A CE2 1 
ATOM   1398  C  CE3 . TRP A 1 193 ? 18.950  34.544  13.371  1.00 19.35  ? 193 TRP A CE3 1 
ATOM   1399  C  CZ2 . TRP A 1 193 ? 20.331  32.678  15.000  1.00 22.28  ? 193 TRP A CZ2 1 
ATOM   1400  C  CZ3 . TRP A 1 193 ? 19.425  34.891  14.608  1.00 20.14  ? 193 TRP A CZ3 1 
ATOM   1401  C  CH2 . TRP A 1 193 ? 20.094  33.975  15.411  1.00 21.82  ? 193 TRP A CH2 1 
ATOM   1402  N  N   . GLU A 1 194 ? 20.133  32.989  8.221   1.00 29.16  ? 194 GLU A N   1 
ATOM   1403  C  CA  . GLU A 1 194 ? 21.333  32.392  7.683   1.00 29.63  ? 194 GLU A CA  1 
ATOM   1404  C  C   . GLU A 1 194 ? 22.140  33.455  6.956   1.00 25.16  ? 194 GLU A C   1 
ATOM   1405  O  O   . GLU A 1 194 ? 23.260  33.212  6.576   1.00 24.00  ? 194 GLU A O   1 
ATOM   1406  C  CB  . GLU A 1 194 ? 20.965  31.231  6.762   1.00 38.87  ? 194 GLU A CB  1 
ATOM   1407  C  CG  . GLU A 1 194 ? 21.774  29.978  7.067   1.00 53.67  ? 194 GLU A CG  1 
ATOM   1408  C  CD  . GLU A 1 194 ? 20.791  28.857  7.148   1.00 59.84  ? 194 GLU A CD  1 
ATOM   1409  O  OE1 . GLU A 1 194 ? 20.124  28.538  6.143   1.00 64.23  ? 194 GLU A OE1 1 
ATOM   1410  O  OE2 . GLU A 1 194 ? 20.695  28.369  8.286   1.00 70.75  ? 194 GLU A OE2 1 
ATOM   1411  N  N   . GLY A 1 195 ? 21.602  34.652  6.789   1.00 26.25  ? 195 GLY A N   1 
ATOM   1412  C  CA  . GLY A 1 195 ? 22.384  35.727  6.206   1.00 26.78  ? 195 GLY A CA  1 
ATOM   1413  C  C   . GLY A 1 195 ? 23.269  36.436  7.219   1.00 29.03  ? 195 GLY A C   1 
ATOM   1414  O  O   . GLY A 1 195 ? 24.073  37.258  6.829   1.00 29.70  ? 195 GLY A O   1 
ATOM   1415  N  N   . LEU A 1 196 ? 23.074  36.190  8.522   1.00 29.65  ? 196 LEU A N   1 
ATOM   1416  C  CA  . LEU A 1 196 ? 23.932  36.776  9.532   1.00 26.11  ? 196 LEU A CA  1 
ATOM   1417  C  C   . LEU A 1 196 ? 25.191  35.948  9.644   1.00 24.42  ? 196 LEU A C   1 
ATOM   1418  O  O   . LEU A 1 196 ? 25.131  34.756  9.438   1.00 26.80  ? 196 LEU A O   1 
ATOM   1419  C  CB  . LEU A 1 196 ? 23.191  36.818  10.860  1.00 27.71  ? 196 LEU A CB  1 
ATOM   1420  C  CG  . LEU A 1 196 ? 22.364  38.085  11.095  1.00 31.70  ? 196 LEU A CG  1 
ATOM   1421  C  CD1 . LEU A 1 196 ? 21.395  38.264  9.994   1.00 38.60  ? 196 LEU A CD1 1 
ATOM   1422  C  CD2 . LEU A 1 196 ? 21.636  38.001  12.398  1.00 34.47  ? 196 LEU A CD2 1 
ATOM   1423  N  N   . SER A 1 197 ? 26.308  36.574  10.025  1.00 25.29  ? 197 SER A N   1 
ATOM   1424  C  CA  . SER A 1 197 ? 27.471  35.809  10.455  1.00 22.41  ? 197 SER A CA  1 
ATOM   1425  C  C   . SER A 1 197 ? 27.151  35.095  11.766  1.00 23.95  ? 197 SER A C   1 
ATOM   1426  O  O   . SER A 1 197 ? 26.211  35.447  12.469  1.00 23.30  ? 197 SER A O   1 
ATOM   1427  C  CB  . SER A 1 197 ? 28.622  36.698  10.650  1.00 22.64  ? 197 SER A CB  1 
ATOM   1428  O  OG  . SER A 1 197 ? 28.378  37.581  11.742  1.00 24.71  ? 197 SER A OG  1 
ATOM   1429  N  N   . VAL A 1 198 ? 27.960  34.110  12.131  1.00 23.62  ? 198 VAL A N   1 
ATOM   1430  C  CA  . VAL A 1 198 ? 27.781  33.457  13.410  1.00 24.06  ? 198 VAL A CA  1 
ATOM   1431  C  C   . VAL A 1 198 ? 27.879  34.481  14.550  1.00 25.01  ? 198 VAL A C   1 
ATOM   1432  O  O   . VAL A 1 198 ? 27.132  34.376  15.522  1.00 25.46  ? 198 VAL A O   1 
ATOM   1433  C  CB  . VAL A 1 198 ? 28.815  32.334  13.603  1.00 23.94  ? 198 VAL A CB  1 
ATOM   1434  C  CG1 . VAL A 1 198 ? 28.839  31.819  15.039  1.00 28.62  ? 198 VAL A CG1 1 
ATOM   1435  C  CG2 . VAL A 1 198 ? 28.581  31.168  12.685  1.00 23.77  ? 198 VAL A CG2 1 
ATOM   1436  N  N   . GLU A 1 199 ? 28.797  35.452  14.459  1.00 25.48  ? 199 GLU A N   1 
ATOM   1437  C  CA  . GLU A 1 199 ? 29.068  36.366  15.567  1.00 28.63  ? 199 GLU A CA  1 
ATOM   1438  C  C   . GLU A 1 199 ? 27.835  37.232  15.774  1.00 28.26  ? 199 GLU A C   1 
ATOM   1439  O  O   . GLU A 1 199 ? 27.448  37.485  16.903  1.00 33.88  ? 199 GLU A O   1 
ATOM   1440  C  CB  . GLU A 1 199 ? 30.322  37.233  15.378  1.00 34.18  ? 199 GLU A CB  1 
ATOM   1441  C  CG  . GLU A 1 199 ? 31.621  36.420  15.246  1.00 45.39  ? 199 GLU A CG  1 
ATOM   1442  C  CD  . GLU A 1 199 ? 31.861  35.359  14.125  1.00 42.80  ? 199 GLU A CD  1 
ATOM   1443  O  OE1 . GLU A 1 199 ? 31.350  35.553  12.964  1.00 32.09  ? 199 GLU A OE1 1 
ATOM   1444  O  OE2 . GLU A 1 199 ? 32.564  34.324  14.415  1.00 38.56  ? 199 GLU A OE2 1 
ATOM   1445  N  N   . ALA A 1 200 ? 27.157  37.580  14.682  1.00 26.54  ? 200 ALA A N   1 
ATOM   1446  C  CA  . ALA A 1 200 ? 25.927  38.360  14.726  1.00 25.27  ? 200 ALA A CA  1 
ATOM   1447  C  C   . ALA A 1 200 ? 24.795  37.560  15.361  1.00 29.19  ? 200 ALA A C   1 
ATOM   1448  O  O   . ALA A 1 200 ? 23.988  38.131  16.101  1.00 33.86  ? 200 ALA A O   1 
ATOM   1449  C  CB  . ALA A 1 200 ? 25.524  38.774  13.316  1.00 25.61  ? 200 ALA A CB  1 
ATOM   1450  N  N   . GLN A 1 201 ? 24.722  36.260  15.034  1.00 23.97  ? 201 GLN A N   1 
ATOM   1451  C  CA  . GLN A 1 201 ? 23.692  35.411  15.586  1.00 25.22  ? 201 GLN A CA  1 
ATOM   1452  C  C   . GLN A 1 201 ? 23.899  35.285  17.090  1.00 25.22  ? 201 GLN A C   1 
ATOM   1453  O  O   . GLN A 1 201 ? 22.924  35.260  17.845  1.00 28.46  ? 201 GLN A O   1 
ATOM   1454  C  CB  . GLN A 1 201 ? 23.730  34.017  14.968  1.00 26.67  ? 201 GLN A CB  1 
ATOM   1455  C  CG  . GLN A 1 201 ? 23.383  33.950  13.490  1.00 26.24  ? 201 GLN A CG  1 
ATOM   1456  C  CD  . GLN A 1 201 ? 23.346  32.537  12.974  1.00 24.41  ? 201 GLN A CD  1 
ATOM   1457  O  OE1 . GLN A 1 201 ? 23.812  31.586  13.613  1.00 23.26  ? 201 GLN A OE1 1 
ATOM   1458  N  NE2 . GLN A 1 201 ? 22.752  32.386  11.807  1.00 24.66  ? 201 GLN A NE2 1 
ATOM   1459  N  N   . GLU A 1 202 ? 25.161  35.194  17.509  1.00 22.89  ? 202 GLU A N   1 
ATOM   1460  C  CA  . GLU A 1 202 ? 25.475  35.044  18.929  1.00 24.53  ? 202 GLU A CA  1 
ATOM   1461  C  C   . GLU A 1 202 ? 25.041  36.280  19.716  1.00 24.22  ? 202 GLU A C   1 
ATOM   1462  O  O   . GLU A 1 202 ? 24.689  36.182  20.892  1.00 20.62  ? 202 GLU A O   1 
ATOM   1463  C  CB  . GLU A 1 202 ? 26.972  34.776  19.120  1.00 24.49  ? 202 GLU A CB  1 
ATOM   1464  C  CG  . GLU A 1 202 ? 27.391  33.357  18.714  1.00 25.02  ? 202 GLU A CG  1 
ATOM   1465  C  CD  . GLU A 1 202 ? 28.888  33.138  18.661  1.00 26.55  ? 202 GLU A CD  1 
ATOM   1466  O  OE1 . GLU A 1 202 ? 29.644  34.152  18.586  1.00 27.49  ? 202 GLU A OE1 1 
ATOM   1467  O  OE2 . GLU A 1 202 ? 29.295  31.965  18.751  1.00 25.55  ? 202 GLU A OE2 1 
ATOM   1468  N  N   . ARG A 1 203 ? 25.074  37.435  19.033  1.00 25.37  ? 203 ARG A N   1 
ATOM   1469  C  CA  . ARG A 1 203 ? 24.694  38.700  19.630  1.00 27.64  ? 203 ARG A CA  1 
ATOM   1470  C  C   . ARG A 1 203 ? 23.190  38.768  19.750  1.00 25.33  ? 203 ARG A C   1 
ATOM   1471  O  O   . ARG A 1 203 ? 22.675  39.435  20.617  1.00 28.13  ? 203 ARG A O   1 
ATOM   1472  C  CB  . ARG A 1 203 ? 25.277  39.881  18.848  1.00 30.74  ? 203 ARG A CB  1 
ATOM   1473  C  CG  . ARG A 1 203 ? 26.721  40.091  19.328  1.00 38.03  ? 203 ARG A CG  1 
ATOM   1474  C  CD  . ARG A 1 203 ? 27.428  41.467  19.259  1.00 44.83  ? 203 ARG A CD  1 
ATOM   1475  N  NE  . ARG A 1 203 ? 27.420  42.029  17.907  1.00 48.78  ? 203 ARG A NE  1 
ATOM   1476  N  N   . VAL A 1 204 ? 22.493  38.106  18.850  1.00 23.53  ? 204 VAL A N   1 
ATOM   1477  C  CA  . VAL A 1 204 ? 21.038  38.003  18.956  1.00 26.71  ? 204 VAL A CA  1 
ATOM   1478  C  C   . VAL A 1 204 ? 20.601  37.103  20.130  1.00 26.19  ? 204 VAL A C   1 
ATOM   1479  O  O   . VAL A 1 204 ? 19.675  37.428  20.853  1.00 24.36  ? 204 VAL A O   1 
ATOM   1480  C  CB  . VAL A 1 204 ? 20.448  37.512  17.627  1.00 23.67  ? 204 VAL A CB  1 
ATOM   1481  C  CG1 . VAL A 1 204 ? 18.970  37.215  17.772  1.00 22.52  ? 204 VAL A CG1 1 
ATOM   1482  C  CG2 . VAL A 1 204 ? 20.725  38.541  16.534  1.00 25.25  ? 204 VAL A CG2 1 
ATOM   1483  N  N   . ILE A 1 205 ? 21.252  35.959  20.323  1.00 24.02  ? 205 ILE A N   1 
ATOM   1484  C  CA  . ILE A 1 205 ? 20.827  35.018  21.337  1.00 23.70  ? 205 ILE A CA  1 
ATOM   1485  C  C   . ILE A 1 205 ? 21.414  35.416  22.694  1.00 21.00  ? 205 ILE A C   1 
ATOM   1486  O  O   . ILE A 1 205 ? 20.705  35.421  23.693  1.00 21.90  ? 205 ILE A O   1 
ATOM   1487  C  CB  . ILE A 1 205 ? 21.233  33.593  20.916  1.00 24.78  ? 205 ILE A CB  1 
ATOM   1488  C  CG1 . ILE A 1 205 ? 20.581  33.197  19.620  1.00 24.70  ? 205 ILE A CG1 1 
ATOM   1489  C  CG2 . ILE A 1 205 ? 20.948  32.558  22.013  1.00 26.37  ? 205 ILE A CG2 1 
ATOM   1490  C  CD1 . ILE A 1 205 ? 19.081  33.020  19.690  1.00 25.10  ? 205 ILE A CD1 1 
ATOM   1491  N  N   . GLY A 1 206 ? 22.723  35.685  22.722  1.00 21.44  ? 206 GLY A N   1 
ATOM   1492  C  CA  . GLY A 1 206 ? 23.429  36.037  23.940  1.00 20.75  ? 206 GLY A CA  1 
ATOM   1493  C  C   . GLY A 1 206 ? 24.325  34.912  24.435  1.00 21.90  ? 206 GLY A C   1 
ATOM   1494  O  O   . GLY A 1 206 ? 24.836  34.974  25.544  1.00 28.19  ? 206 GLY A O   1 
ATOM   1495  N  N   . ARG A 1 207 ? 24.514  33.879  23.625  1.00 22.59  ? 207 ARG A N   1 
ATOM   1496  C  CA  . ARG A 1 207 ? 25.408  32.790  23.965  1.00 23.11  ? 207 ARG A CA  1 
ATOM   1497  C  C   . ARG A 1 207 ? 26.201  32.409  22.719  1.00 25.06  ? 207 ARG A C   1 
ATOM   1498  O  O   . ARG A 1 207 ? 25.825  32.762  21.616  1.00 26.41  ? 207 ARG A O   1 
ATOM   1499  C  CB  . ARG A 1 207 ? 24.602  31.555  24.385  1.00 23.36  ? 207 ARG A CB  1 
ATOM   1500  C  CG  . ARG A 1 207 ? 23.577  31.816  25.473  1.00 24.25  ? 207 ARG A CG  1 
ATOM   1501  C  CD  . ARG A 1 207 ? 22.876  30.578  25.958  1.00 27.27  ? 207 ARG A CD  1 
ATOM   1502  N  NE  . ARG A 1 207 ? 23.738  29.644  26.707  1.00 30.79  ? 207 ARG A NE  1 
ATOM   1503  C  CZ  . ARG A 1 207 ? 23.974  29.650  28.019  1.00 33.06  ? 207 ARG A CZ  1 
ATOM   1504  N  NH1 . ARG A 1 207 ? 23.427  30.529  28.851  1.00 33.40  ? 207 ARG A NH1 1 
ATOM   1505  N  NH2 . ARG A 1 207 ? 24.749  28.716  28.525  1.00 35.11  ? 207 ARG A NH2 1 
ATOM   1506  N  N   . ARG A 1 208 ? 27.269  31.638  22.908  1.00 28.40  ? 208 ARG A N   1 
ATOM   1507  C  CA  . ARG A 1 208 ? 28.118  31.164  21.821  1.00 27.96  ? 208 ARG A CA  1 
ATOM   1508  C  C   . ARG A 1 208 ? 27.433  30.008  21.113  1.00 24.07  ? 208 ARG A C   1 
ATOM   1509  O  O   . ARG A 1 208 ? 26.861  29.128  21.740  1.00 23.96  ? 208 ARG A O   1 
ATOM   1510  C  CB  . ARG A 1 208 ? 29.471  30.595  22.305  1.00 32.58  ? 208 ARG A CB  1 
ATOM   1511  C  CG  . ARG A 1 208 ? 30.355  31.541  23.109  1.00 34.61  ? 208 ARG A CG  1 
ATOM   1512  C  CD  . ARG A 1 208 ? 30.628  32.889  22.415  1.00 38.67  ? 208 ARG A CD  1 
ATOM   1513  N  NE  . ARG A 1 208 ? 31.314  32.753  21.131  1.00 46.28  ? 208 ARG A NE  1 
ATOM   1514  C  CZ  . ARG A 1 208 ? 32.565  32.283  21.045  1.00 54.13  ? 208 ARG A CZ  1 
ATOM   1515  N  NH1 . ARG A 1 208 ? 33.003  31.678  19.944  1.00 45.54  ? 208 ARG A NH1 1 
ATOM   1516  N  NH2 . ARG A 1 208 ? 33.339  32.290  22.127  1.00 56.37  ? 208 ARG A NH2 1 
ATOM   1517  N  N   . LYS A 1 209 ? 27.561  29.971  19.798  1.00 21.72  ? 209 LYS A N   1 
ATOM   1518  C  CA  . LYS A 1 209 ? 26.813  28.997  19.026  1.00 23.77  ? 209 LYS A CA  1 
ATOM   1519  C  C   . LYS A 1 209 ? 27.330  27.579  19.263  1.00 23.27  ? 209 LYS A C   1 
ATOM   1520  O  O   . LYS A 1 209 ? 26.541  26.741  19.712  1.00 26.84  ? 209 LYS A O   1 
ATOM   1521  C  CB  . LYS A 1 209 ? 26.800  29.354  17.533  1.00 23.75  ? 209 LYS A CB  1 
ATOM   1522  C  CG  . LYS A 1 209 ? 25.772  28.560  16.812  1.00 24.82  ? 209 LYS A CG  1 
ATOM   1523  C  CD  . LYS A 1 209 ? 25.546  29.081  15.403  1.00 30.27  ? 209 LYS A CD  1 
ATOM   1524  C  CE  . LYS A 1 209 ? 24.293  28.478  14.835  1.00 32.01  ? 209 LYS A CE  1 
ATOM   1525  N  NZ  . LYS A 1 209 ? 24.154  28.809  13.408  1.00 30.56  ? 209 LYS A NZ  1 
ATOM   1526  N  N   . MET A 1 210 ? 28.620  27.316  18.974  1.00 22.63  ? 210 MET A N   1 
ATOM   1527  C  CA  . MET A 1 210 ? 29.078  25.921  19.005  1.00 26.19  ? 210 MET A CA  1 
ATOM   1528  C  C   . MET A 1 210 ? 29.246  25.450  20.443  1.00 25.10  ? 210 MET A C   1 
ATOM   1529  O  O   . MET A 1 210 ? 28.793  24.370  20.730  1.00 29.88  ? 210 MET A O   1 
ATOM   1530  C  CB  . MET A 1 210 ? 30.326  25.519  18.187  1.00 31.31  ? 210 MET A CB  1 
ATOM   1531  C  CG  . MET A 1 210 ? 30.387  25.974  16.665  1.00 41.17  ? 210 MET A CG  1 
ATOM   1532  S  SD  . MET A 1 210 ? 29.215  25.591  15.307  1.00 59.41  ? 210 MET A SD  1 
ATOM   1533  C  CE  . MET A 1 210 ? 29.050  27.016  14.212  1.00 51.22  ? 210 MET A CE  1 
ATOM   1534  N  N   . THR A 1 211 ? 29.789  26.244  21.368  1.00 26.79  ? 211 THR A N   1 
ATOM   1535  C  CA  . THR A 1 211 ? 30.063  25.789  22.727  1.00 26.77  ? 211 THR A CA  1 
ATOM   1536  C  C   . THR A 1 211 ? 28.925  26.036  23.731  1.00 28.91  ? 211 THR A C   1 
ATOM   1537  O  O   . THR A 1 211 ? 28.948  25.471  24.823  1.00 27.57  ? 211 THR A O   1 
ATOM   1538  C  CB  . THR A 1 211 ? 31.358  26.425  23.212  1.00 28.52  ? 211 THR A CB  1 
ATOM   1539  O  OG1 . THR A 1 211 ? 31.132  27.830  23.294  1.00 32.06  ? 211 THR A OG1 1 
ATOM   1540  C  CG2 . THR A 1 211 ? 32.506  26.026  22.300  1.00 30.91  ? 211 THR A CG2 1 
ATOM   1541  N  N   . ASP A 1 212 ? 27.950  26.888  23.399  1.00 27.22  ? 212 ASP A N   1 
ATOM   1542  C  CA  . ASP A 1 212 ? 26.841  27.209  24.298  1.00 26.95  ? 212 ASP A CA  1 
ATOM   1543  C  C   . ASP A 1 212 ? 27.307  27.842  25.609  1.00 25.88  ? 212 ASP A C   1 
ATOM   1544  O  O   . ASP A 1 212 ? 26.654  27.691  26.626  1.00 29.36  ? 212 ASP A O   1 
ATOM   1545  C  CB  . ASP A 1 212 ? 26.025  25.992  24.691  1.00 26.47  ? 212 ASP A CB  1 
ATOM   1546  C  CG  . ASP A 1 212 ? 24.636  26.223  25.268  1.00 26.83  ? 212 ASP A CG  1 
ATOM   1547  O  OD1 . ASP A 1 212 ? 24.002  27.312  24.959  1.00 24.14  ? 212 ASP A OD1 1 
ATOM   1548  O  OD2 . ASP A 1 212 ? 24.207  25.220  25.935  1.00 29.95  ? 212 ASP A OD2 1 
ATOM   1549  N  N   . VAL A 1 213 ? 28.413  28.574  25.584  1.00 26.73  ? 213 VAL A N   1 
ATOM   1550  C  CA  . VAL A 1 213 ? 28.835  29.364  26.722  1.00 26.97  ? 213 VAL A CA  1 
ATOM   1551  C  C   . VAL A 1 213 ? 28.209  30.754  26.647  1.00 29.22  ? 213 VAL A C   1 
ATOM   1552  O  O   . VAL A 1 213 ? 28.251  31.405  25.607  1.00 28.78  ? 213 VAL A O   1 
ATOM   1553  C  CB  . VAL A 1 213 ? 30.371  29.454  26.741  1.00 28.06  ? 213 VAL A CB  1 
ATOM   1554  C  CG1 . VAL A 1 213 ? 30.881  30.386  27.830  1.00 27.17  ? 213 VAL A CG1 1 
ATOM   1555  C  CG2 . VAL A 1 213 ? 30.981  28.064  26.886  1.00 29.23  ? 213 VAL A CG2 1 
ATOM   1556  N  N   . GLU A 1 214 ? 27.689  31.239  27.775  1.00 27.32  ? 214 GLU A N   1 
ATOM   1557  C  CA  . GLU A 1 214 ? 27.050  32.546  27.818  1.00 30.64  ? 214 GLU A CA  1 
ATOM   1558  C  C   . GLU A 1 214 ? 28.046  33.642  27.444  1.00 27.41  ? 214 GLU A C   1 
ATOM   1559  O  O   . GLU A 1 214 ? 29.197  33.558  27.781  1.00 24.59  ? 214 GLU A O   1 
ATOM   1560  C  CB  . GLU A 1 214 ? 26.584  32.720  29.259  1.00 39.38  ? 214 GLU A CB  1 
ATOM   1561  C  CG  . GLU A 1 214 ? 25.644  33.904  29.449  1.00 40.54  ? 214 GLU A CG  1 
ATOM   1562  C  CD  . GLU A 1 214 ? 24.845  33.809  30.727  1.00 41.40  ? 214 GLU A CD  1 
ATOM   1563  O  OE1 . GLU A 1 214 ? 24.705  32.753  31.394  1.00 44.83  ? 214 GLU A OE1 1 
ATOM   1564  O  OE2 . GLU A 1 214 ? 24.314  34.864  31.016  1.00 35.42  ? 214 GLU A OE2 1 
ATOM   1565  N  N   . LEU A 1 215 ? 27.622  34.667  26.720  1.00 28.11  ? 215 LEU A N   1 
ATOM   1566  C  CA  . LEU A 1 215 ? 28.491  35.801  26.477  1.00 33.42  ? 215 LEU A CA  1 
ATOM   1567  C  C   . LEU A 1 215 ? 28.671  36.532  27.804  1.00 39.77  ? 215 LEU A C   1 
ATOM   1568  O  O   . LEU A 1 215 ? 27.722  36.640  28.590  1.00 42.92  ? 215 LEU A O   1 
ATOM   1569  C  CB  . LEU A 1 215 ? 27.903  36.742  25.424  1.00 35.06  ? 215 LEU A CB  1 
ATOM   1570  C  CG  . LEU A 1 215 ? 27.745  36.207  23.995  1.00 31.55  ? 215 LEU A CG  1 
ATOM   1571  C  CD1 . LEU A 1 215 ? 27.371  37.291  23.000  1.00 32.91  ? 215 LEU A CD1 1 
ATOM   1572  C  CD2 . LEU A 1 215 ? 28.943  35.521  23.521  1.00 30.05  ? 215 LEU A CD2 1 
ATOM   1573  N  N   . SER A 1 216 ? 29.867  37.098  28.026  1.00 40.03  ? 216 SER A N   1 
ATOM   1574  C  CA  . SER A 1 216 ? 30.131  37.850  29.244  1.00 41.33  ? 216 SER A CA  1 
ATOM   1575  C  C   . SER A 1 216 ? 29.304  39.128  29.222  1.00 43.89  ? 216 SER A C   1 
ATOM   1576  O  O   . SER A 1 216 ? 28.967  39.648  28.156  1.00 43.28  ? 216 SER A O   1 
ATOM   1577  C  CB  . SER A 1 216 ? 31.592  38.164  29.410  1.00 48.89  ? 216 SER A CB  1 
ATOM   1578  O  OG  . SER A 1 216 ? 32.051  38.934  28.306  1.00 56.94  ? 216 SER A OG  1 
ATOM   1579  N  N   . ASP A 1 217 ? 29.011  39.636  30.426  1.00 56.50  ? 217 ASP A N   1 
ATOM   1580  C  CA  . ASP A 1 217 ? 28.133  40.777  30.621  1.00 53.44  ? 217 ASP A CA  1 
ATOM   1581  C  C   . ASP A 1 217 ? 28.708  42.003  29.936  1.00 53.34  ? 217 ASP A C   1 
ATOM   1582  O  O   . ASP A 1 217 ? 27.946  42.841  29.495  1.00 54.52  ? 217 ASP A O   1 
ATOM   1583  C  CB  . ASP A 1 217 ? 27.869  40.990  32.096  1.00 59.32  ? 217 ASP A CB  1 
ATOM   1584  C  CG  . ASP A 1 217 ? 27.098  39.829  32.721  1.00 67.28  ? 217 ASP A CG  1 
ATOM   1585  O  OD1 . ASP A 1 217 ? 26.007  39.513  32.216  1.00 62.79  ? 217 ASP A OD1 1 
ATOM   1586  O  OD2 . ASP A 1 217 ? 27.607  39.206  33.679  1.00 85.85  ? 217 ASP A OD2 1 
ATOM   1587  N  N   . ASP A 1 218 ? 30.030  42.078  29.792  1.00 52.69  ? 218 ASP A N   1 
ATOM   1588  C  CA  . ASP A 1 218 ? 30.644  43.223  29.143  1.00 58.47  ? 218 ASP A CA  1 
ATOM   1589  C  C   . ASP A 1 218 ? 30.408  43.177  27.626  1.00 60.11  ? 218 ASP A C   1 
ATOM   1590  O  O   . ASP A 1 218 ? 30.638  44.177  26.968  1.00 70.35  ? 218 ASP A O   1 
ATOM   1591  C  CB  . ASP A 1 218 ? 32.077  43.442  29.628  1.00 64.33  ? 218 ASP A CB  1 
ATOM   1592  C  CG  . ASP A 1 218 ? 33.075  42.328  29.327  1.00 78.17  ? 218 ASP A CG  1 
ATOM   1593  O  OD1 . ASP A 1 218 ? 33.059  41.795  28.197  1.00 79.15  ? 218 ASP A OD1 1 
ATOM   1594  O  OD2 . ASP A 1 218 ? 33.851  41.955  30.240  1.00 89.96  ? 218 ASP A OD2 1 
ATOM   1595  N  N   . VAL A 1 219 ? 29.907  42.081  27.034  1.00 54.52  ? 219 VAL A N   1 
ATOM   1596  C  CA  . VAL A 1 219 ? 29.704  42.096  25.587  1.00 48.11  ? 219 VAL A CA  1 
ATOM   1597  C  C   . VAL A 1 219 ? 28.280  41.667  25.214  1.00 44.64  ? 219 VAL A C   1 
ATOM   1598  O  O   . VAL A 1 219 ? 27.884  41.769  24.066  1.00 44.09  ? 219 VAL A O   1 
ATOM   1599  C  CB  . VAL A 1 219 ? 30.760  41.249  24.844  1.00 46.02  ? 219 VAL A CB  1 
ATOM   1600  C  CG1 . VAL A 1 219 ? 32.091  41.202  25.575  1.00 51.10  ? 219 VAL A CG1 1 
ATOM   1601  C  CG2 . VAL A 1 219 ? 30.305  39.819  24.592  1.00 44.73  ? 219 VAL A CG2 1 
ATOM   1602  N  N   . LYS A 1 220 ? 27.491  41.161  26.152  1.00 42.52  ? 220 LYS A N   1 
ATOM   1603  C  CA  . LYS A 1 220 ? 26.191  40.637  25.791  1.00 39.54  ? 220 LYS A CA  1 
ATOM   1604  C  C   . LYS A 1 220 ? 25.252  41.798  25.539  1.00 35.03  ? 220 LYS A C   1 
ATOM   1605  O  O   . LYS A 1 220 ? 25.001  42.562  26.454  1.00 38.58  ? 220 LYS A O   1 
ATOM   1606  C  CB  . LYS A 1 220 ? 25.671  39.799  26.959  1.00 44.05  ? 220 LYS A CB  1 
ATOM   1607  C  CG  . LYS A 1 220 ? 24.279  39.148  26.715  1.00 49.41  ? 220 LYS A CG  1 
ATOM   1608  C  CD  . LYS A 1 220 ? 23.647  38.423  27.891  1.00 45.60  ? 220 LYS A CD  1 
ATOM   1609  C  CE  . LYS A 1 220 ? 24.679  38.030  28.855  1.00 45.73  ? 220 LYS A CE  1 
ATOM   1610  N  NZ  . LYS A 1 220 ? 24.187  37.017  29.773  1.00 48.75  ? 220 LYS A NZ  1 
ATOM   1611  N  N   . PRO A 1 221 ? 24.709  41.998  24.323  1.00 35.26  ? 221 PRO A N   1 
ATOM   1612  C  CA  . PRO A 1 221 ? 23.779  43.106  24.086  1.00 36.14  ? 221 PRO A CA  1 
ATOM   1613  C  C   . PRO A 1 221 ? 22.540  43.090  24.987  1.00 39.59  ? 221 PRO A C   1 
ATOM   1614  O  O   . PRO A 1 221 ? 22.071  42.027  25.392  1.00 37.68  ? 221 PRO A O   1 
ATOM   1615  C  CB  . PRO A 1 221 ? 23.410  42.971  22.605  1.00 36.98  ? 221 PRO A CB  1 
ATOM   1616  C  CG  . PRO A 1 221 ? 24.513  42.159  22.000  1.00 33.81  ? 221 PRO A CG  1 
ATOM   1617  C  CD  . PRO A 1 221 ? 24.996  41.231  23.108  1.00 35.43  ? 221 PRO A CD  1 
ATOM   1618  N  N   . ALA A 1 222 ? 22.003  44.283  25.268  1.00 36.38  ? 222 ALA A N   1 
ATOM   1619  C  CA  . ALA A 1 222 ? 20.790  44.445  26.053  1.00 36.01  ? 222 ALA A CA  1 
ATOM   1620  C  C   . ALA A 1 222 ? 19.559  43.941  25.307  1.00 34.87  ? 222 ALA A C   1 
ATOM   1621  O  O   . ALA A 1 222 ? 18.546  43.671  25.946  1.00 35.46  ? 222 ALA A O   1 
ATOM   1622  C  CB  . ALA A 1 222 ? 20.588  45.904  26.381  1.00 36.58  ? 222 ALA A CB  1 
ATOM   1623  N  N   . ASP A 1 223 ? 19.629  43.842  23.972  1.00 35.19  ? 223 ASP A N   1 
ATOM   1624  C  CA  . ASP A 1 223 ? 18.488  43.367  23.203  1.00 34.19  ? 223 ASP A CA  1 
ATOM   1625  C  C   . ASP A 1 223 ? 18.682  41.909  22.754  1.00 28.52  ? 223 ASP A C   1 
ATOM   1626  O  O   . ASP A 1 223 ? 17.924  41.402  21.899  1.00 25.49  ? 223 ASP A O   1 
ATOM   1627  C  CB  . ASP A 1 223 ? 18.140  44.305  22.057  1.00 36.37  ? 223 ASP A CB  1 
ATOM   1628  C  CG  . ASP A 1 223 ? 19.208  44.446  20.983  1.00 34.54  ? 223 ASP A CG  1 
ATOM   1629  O  OD1 . ASP A 1 223 ? 20.362  44.008  21.213  1.00 33.18  ? 223 ASP A OD1 1 
ATOM   1630  O  OD2 . ASP A 1 223 ? 18.869  45.019  19.945  1.00 40.56  ? 223 ASP A OD2 1 
ATOM   1631  N  N   . SER A 1 224 ? 19.650  41.227  23.383  1.00 22.95  ? 224 SER A N   1 
ATOM   1632  C  CA  . SER A 1 224 ? 19.799  39.805  23.162  1.00 25.65  ? 224 SER A CA  1 
ATOM   1633  C  C   . SER A 1 224 ? 18.711  39.066  23.924  1.00 25.52  ? 224 SER A C   1 
ATOM   1634  O  O   . SER A 1 224 ? 18.175  39.581  24.902  1.00 27.49  ? 224 SER A O   1 
ATOM   1635  C  CB  . SER A 1 224 ? 21.166  39.336  23.555  1.00 28.40  ? 224 SER A CB  1 
ATOM   1636  O  OG  . SER A 1 224 ? 21.333  39.401  24.962  1.00 25.56  ? 224 SER A OG  1 
ATOM   1637  N  N   . HIS A 1 225 ? 18.400  37.859  23.462  1.00 23.25  ? 225 HIS A N   1 
ATOM   1638  C  CA  . HIS A 1 225 ? 17.277  37.088  23.958  1.00 23.33  ? 225 HIS A CA  1 
ATOM   1639  C  C   . HIS A 1 225 ? 17.513  36.720  25.421  1.00 27.03  ? 225 HIS A C   1 
ATOM   1640  O  O   . HIS A 1 225 ? 16.583  36.805  26.234  1.00 26.05  ? 225 HIS A O   1 
ATOM   1641  C  CB  . HIS A 1 225 ? 17.048  35.868  23.067  1.00 24.04  ? 225 HIS A CB  1 
ATOM   1642  C  CG  . HIS A 1 225 ? 15.985  34.948  23.548  1.00 21.35  ? 225 HIS A CG  1 
ATOM   1643  N  ND1 . HIS A 1 225 ? 14.677  35.333  23.659  1.00 18.75  ? 225 HIS A ND1 1 
ATOM   1644  C  CD2 . HIS A 1 225 ? 16.019  33.678  23.942  1.00 21.89  ? 225 HIS A CD2 1 
ATOM   1645  C  CE1 . HIS A 1 225 ? 13.958  34.309  24.087  1.00 18.75  ? 225 HIS A CE1 1 
ATOM   1646  N  NE2 . HIS A 1 225 ? 14.755  33.293  24.274  1.00 18.89  ? 225 HIS A NE2 1 
ATOM   1647  N  N   . VAL A 1 226 ? 18.760  36.361  25.750  1.00 25.11  ? 226 VAL A N   1 
ATOM   1648  C  CA  . VAL A 1 226 ? 19.093  35.941  27.101  1.00 29.35  ? 226 VAL A CA  1 
ATOM   1649  C  C   . VAL A 1 226 ? 19.070  37.129  28.050  1.00 26.00  ? 226 VAL A C   1 
ATOM   1650  O  O   . VAL A 1 226 ? 18.758  36.988  29.224  1.00 27.96  ? 226 VAL A O   1 
ATOM   1651  C  CB  . VAL A 1 226 ? 20.455  35.216  27.112  1.00 31.10  ? 226 VAL A CB  1 
ATOM   1652  C  CG1 . VAL A 1 226 ? 21.109  35.264  28.482  1.00 34.98  ? 226 VAL A CG1 1 
ATOM   1653  C  CG2 . VAL A 1 226 ? 20.291  33.769  26.639  1.00 31.33  ? 226 VAL A CG2 1 
ATOM   1654  N  N   . ALA A 1 227 ? 19.434  38.290  27.535  1.00 25.59  ? 227 ALA A N   1 
ATOM   1655  C  CA  . ALA A 1 227 ? 19.378  39.510  28.329  1.00 29.76  ? 227 ALA A CA  1 
ATOM   1656  C  C   . ALA A 1 227 ? 17.932  39.832  28.708  1.00 27.73  ? 227 ALA A C   1 
ATOM   1657  O  O   . ALA A 1 227 ? 17.646  40.032  29.869  1.00 27.52  ? 227 ALA A O   1 
ATOM   1658  C  CB  . ALA A 1 227 ? 20.020  40.666  27.574  1.00 29.64  ? 227 ALA A CB  1 
ATOM   1659  N  N   . LEU A 1 228 ? 17.019  39.839  27.740  1.00 26.14  ? 228 LEU A N   1 
ATOM   1660  C  CA  . LEU A 1 228 ? 15.654  40.252  28.004  1.00 26.43  ? 228 LEU A CA  1 
ATOM   1661  C  C   . LEU A 1 228 ? 14.856  39.196  28.759  1.00 25.16  ? 228 LEU A C   1 
ATOM   1662  O  O   . LEU A 1 228 ? 13.846  39.546  29.340  1.00 27.22  ? 228 LEU A O   1 
ATOM   1663  C  CB  . LEU A 1 228 ? 14.939  40.593  26.713  1.00 29.79  ? 228 LEU A CB  1 
ATOM   1664  C  CG  . LEU A 1 228 ? 15.451  41.846  26.012  1.00 38.14  ? 228 LEU A CG  1 
ATOM   1665  C  CD1 . LEU A 1 228 ? 14.917  41.888  24.587  1.00 43.37  ? 228 LEU A CD1 1 
ATOM   1666  C  CD2 . LEU A 1 228 ? 15.025  43.082  26.763  1.00 38.75  ? 228 LEU A CD2 1 
ATOM   1667  N  N   . THR A 1 229 ? 15.233  37.923  28.747  1.00 24.62  ? 229 THR A N   1 
ATOM   1668  C  CA  . THR A 1 229 ? 14.431  36.923  29.433  1.00 25.34  ? 229 THR A CA  1 
ATOM   1669  C  C   . THR A 1 229 ? 15.060  36.569  30.786  1.00 29.13  ? 229 THR A C   1 
ATOM   1670  O  O   . THR A 1 229 ? 14.540  35.670  31.445  1.00 30.40  ? 229 THR A O   1 
ATOM   1671  C  CB  . THR A 1 229 ? 14.252  35.678  28.563  1.00 26.81  ? 229 THR A CB  1 
ATOM   1672  O  OG1 . THR A 1 229 ? 15.546  35.141  28.250  1.00 27.36  ? 229 THR A OG1 1 
ATOM   1673  C  CG2 . THR A 1 229 ? 13.429  35.964  27.318  1.00 25.64  ? 229 THR A CG2 1 
ATOM   1674  N  N   . SER A 1 230 ? 16.130  37.272  31.197  1.00 27.46  ? 230 SER A N   1 
ATOM   1675  C  CA  . SER A 1 230 ? 16.639  37.197  32.555  1.00 32.53  ? 230 SER A CA  1 
ATOM   1676  C  C   . SER A 1 230 ? 15.956  38.271  33.394  1.00 33.43  ? 230 SER A C   1 
ATOM   1677  O  O   . SER A 1 230 ? 16.025  39.444  33.070  1.00 34.63  ? 230 SER A O   1 
ATOM   1678  C  CB  . SER A 1 230 ? 18.120  37.378  32.614  1.00 35.14  ? 230 SER A CB  1 
ATOM   1679  O  OG  . SER A 1 230 ? 18.787  36.306  31.982  1.00 34.08  ? 230 SER A OG  1 
ATOM   1680  N  N   . VAL A 1 231 ? 15.238  37.848  34.428  1.00 32.90  ? 231 VAL A N   1 
ATOM   1681  C  CA  . VAL A 1 231 ? 14.390  38.730  35.206  1.00 38.06  ? 231 VAL A CA  1 
ATOM   1682  C  C   . VAL A 1 231 ? 14.639  38.349  36.653  1.00 38.98  ? 231 VAL A C   1 
ATOM   1683  O  O   . VAL A 1 231 ? 14.698  37.170  36.983  1.00 38.07  ? 231 VAL A O   1 
ATOM   1684  C  CB  . VAL A 1 231 ? 12.906  38.515  34.842  1.00 44.81  ? 231 VAL A CB  1 
ATOM   1685  C  CG1 . VAL A 1 231 ? 11.957  39.142  35.855  1.00 44.47  ? 231 VAL A CG1 1 
ATOM   1686  C  CG2 . VAL A 1 231 ? 12.605  38.980  33.429  1.00 44.14  ? 231 VAL A CG2 1 
ATOM   1687  N  N   . THR A 1 232 ? 14.864  39.346  37.509  1.00 45.90  ? 232 THR A N   1 
ATOM   1688  C  CA  . THR A 1 232 ? 15.030  39.114  38.943  1.00 51.58  ? 232 THR A CA  1 
ATOM   1689  C  C   . THR A 1 232 ? 13.859  39.778  39.674  1.00 46.98  ? 232 THR A C   1 
ATOM   1690  O  O   . THR A 1 232 ? 13.311  40.778  39.197  1.00 36.29  ? 232 THR A O   1 
ATOM   1691  C  CB  . THR A 1 232 ? 16.386  39.614  39.447  1.00 48.79  ? 232 THR A CB  1 
ATOM   1692  O  OG1 . THR A 1 232 ? 16.353  40.882  38.823  1.00 44.38  ? 232 THR A OG1 1 
ATOM   1693  C  CG2 . THR A 1 232 ? 17.558  38.753  39.010  1.00 54.48  ? 232 THR A CG2 1 
ATOM   1694  N  N   . GLY A 1 233 ? 13.460  39.182  40.811  1.00 48.45  ? 233 GLY A N   1 
ATOM   1695  C  CA  . GLY A 1 233 ? 12.331  39.650  41.601  1.00 52.45  ? 233 GLY A CA  1 
ATOM   1696  C  C   . GLY A 1 233 ? 12.725  40.851  42.461  1.00 55.88  ? 233 GLY A C   1 
ATOM   1697  O  O   . GLY A 1 233 ? 13.912  41.180  42.556  1.00 48.56  ? 233 GLY A O   1 
ATOM   1698  N  N   . PRO A 1 234 ? 11.780  41.458  43.219  1.00 56.32  ? 234 PRO A N   1 
ATOM   1699  C  CA  . PRO A 1 234 ? 12.106  42.644  44.028  1.00 55.51  ? 234 PRO A CA  1 
ATOM   1700  C  C   . PRO A 1 234 ? 13.081  42.193  45.125  1.00 52.83  ? 234 PRO A C   1 
ATOM   1701  O  O   . PRO A 1 234 ? 14.036  42.878  45.487  1.00 43.59  ? 234 PRO A O   1 
ATOM   1702  C  CB  . PRO A 1 234 ? 10.786  43.178  44.562  1.00 61.26  ? 234 PRO A CB  1 
ATOM   1703  C  CG  . PRO A 1 234 ? 9.709   42.212  44.014  1.00 67.19  ? 234 PRO A CG  1 
ATOM   1704  C  CD  . PRO A 1 234 ? 10.415  40.968  43.441  1.00 55.37  ? 234 PRO A CD  1 
ATOM   1705  N  N   . ASP A 1 235 ? 12.920  40.955  45.599  1.00 57.37  ? 235 ASP A N   1 
ATOM   1706  C  CA  . ASP A 1 235 ? 13.843  40.401  46.584  1.00 61.43  ? 235 ASP A CA  1 
ATOM   1707  C  C   . ASP A 1 235 ? 15.219  40.047  46.005  1.00 51.15  ? 235 ASP A C   1 
ATOM   1708  O  O   . ASP A 1 235 ? 16.088  39.629  46.745  1.00 48.29  ? 235 ASP A O   1 
ATOM   1709  C  CB  . ASP A 1 235 ? 13.177  39.260  47.333  1.00 77.75  ? 235 ASP A CB  1 
ATOM   1710  C  CG  . ASP A 1 235 ? 13.093  37.927  46.608  1.00 87.70  ? 235 ASP A CG  1 
ATOM   1711  O  OD1 . ASP A 1 235 ? 14.166  37.417  46.215  1.00 88.60  ? 235 ASP A OD1 1 
ATOM   1712  O  OD2 . ASP A 1 235 ? 11.954  37.391  46.509  1.00 79.99  ? 235 ASP A OD2 1 
ATOM   1713  N  N   . GLY A 1 236 ? 15.438  40.158  44.696  1.00 49.48  ? 236 GLY A N   1 
ATOM   1714  C  CA  . GLY A 1 236 ? 16.766  39.980  44.128  1.00 42.70  ? 236 GLY A CA  1 
ATOM   1715  C  C   . GLY A 1 236 ? 16.996  38.578  43.568  1.00 45.72  ? 236 GLY A C   1 
ATOM   1716  O  O   . GLY A 1 236 ? 17.999  38.357  42.896  1.00 57.78  ? 236 GLY A O   1 
ATOM   1717  N  N   . SER A 1 237 ? 16.104  37.617  43.830  1.00 53.92  ? 237 SER A N   1 
ATOM   1718  C  CA  . SER A 1 237 ? 16.274  36.267  43.291  1.00 55.90  ? 237 SER A CA  1 
ATOM   1719  C  C   . SER A 1 237 ? 15.771  36.203  41.845  1.00 51.48  ? 237 SER A C   1 
ATOM   1720  O  O   . SER A 1 237 ? 14.834  36.891  41.464  1.00 42.00  ? 237 SER A O   1 
ATOM   1721  C  CB  . SER A 1 237 ? 15.636  35.199  44.169  1.00 54.48  ? 237 SER A CB  1 
ATOM   1722  O  OG  . SER A 1 237 ? 14.259  35.481  44.353  1.00 55.63  ? 237 SER A OG  1 
ATOM   1723  N  N   . ASP A 1 238 ? 16.425  35.364  41.040  1.00 54.22  ? 238 ASP A N   1 
ATOM   1724  C  CA  . ASP A 1 238 ? 16.022  35.046  39.683  1.00 52.91  ? 238 ASP A CA  1 
ATOM   1725  C  C   . ASP A 1 238 ? 14.588  34.510  39.614  1.00 44.10  ? 238 ASP A C   1 
ATOM   1726  O  O   . ASP A 1 238 ? 14.185  33.664  40.389  1.00 39.19  ? 238 ASP A O   1 
ATOM   1727  C  CB  . ASP A 1 238 ? 16.984  34.009  39.125  1.00 56.44  ? 238 ASP A CB  1 
ATOM   1728  C  CG  . ASP A 1 238 ? 18.357  34.561  38.801  1.00 60.06  ? 238 ASP A CG  1 
ATOM   1729  O  OD1 . ASP A 1 238 ? 18.403  35.628  38.115  1.00 58.77  ? 238 ASP A OD1 1 
ATOM   1730  O  OD2 . ASP A 1 238 ? 19.328  33.899  39.226  1.00 58.70  ? 238 ASP A OD2 1 
ATOM   1731  N  N   . LEU A 1 239 ? 13.809  35.009  38.650  1.00 37.16  ? 239 LEU A N   1 
ATOM   1732  C  CA  . LEU A 1 239 ? 12.496  34.486  38.355  1.00 34.71  ? 239 LEU A CA  1 
ATOM   1733  C  C   . LEU A 1 239 ? 12.666  33.528  37.191  1.00 34.28  ? 239 LEU A C   1 
ATOM   1734  O  O   . LEU A 1 239 ? 13.195  33.911  36.158  1.00 37.68  ? 239 LEU A O   1 
ATOM   1735  C  CB  . LEU A 1 239 ? 11.584  35.643  37.951  1.00 45.38  ? 239 LEU A CB  1 
ATOM   1736  C  CG  . LEU A 1 239 ? 11.203  36.668  39.038  1.00 46.38  ? 239 LEU A CG  1 
ATOM   1737  C  CD1 . LEU A 1 239 ? 10.076  37.495  38.412  1.00 48.42  ? 239 LEU A CD1 1 
ATOM   1738  C  CD2 . LEU A 1 239 ? 10.752  36.089  40.380  1.00 38.37  ? 239 LEU A CD2 1 
ATOM   1739  N  N   . GLU A 1 240 ? 12.208  32.285  37.343  1.00 32.44  ? 240 GLU A N   1 
ATOM   1740  C  CA  . GLU A 1 240 ? 12.557  31.224  36.410  1.00 30.37  ? 240 GLU A CA  1 
ATOM   1741  C  C   . GLU A 1 240 ? 11.305  30.595  35.825  1.00 24.69  ? 240 GLU A C   1 
ATOM   1742  O  O   . GLU A 1 240 ? 10.292  30.528  36.498  1.00 28.58  ? 240 GLU A O   1 
ATOM   1743  C  CB  . GLU A 1 240 ? 13.379  30.192  37.191  1.00 31.97  ? 240 GLU A CB  1 
ATOM   1744  C  CG  . GLU A 1 240 ? 14.671  30.761  37.786  1.00 34.22  ? 240 GLU A CG  1 
ATOM   1745  C  CD  . GLU A 1 240 ? 15.753  29.707  37.905  1.00 40.82  ? 240 GLU A CD  1 
ATOM   1746  O  OE1 . GLU A 1 240 ? 15.757  28.979  38.909  1.00 46.39  ? 240 GLU A OE1 1 
ATOM   1747  O  OE2 . GLU A 1 240 ? 16.524  29.558  36.930  1.00 60.55  ? 240 GLU A OE2 1 
ATOM   1748  N  N   . ILE A 1 241 ? 11.369  30.111  34.599  1.00 22.07  ? 241 ILE A N   1 
ATOM   1749  C  CA  . ILE A 1 241 ? 10.354  29.210  34.061  1.00 22.58  ? 241 ILE A CA  1 
ATOM   1750  C  C   . ILE A 1 241 ? 10.991  27.910  33.567  1.00 21.11  ? 241 ILE A C   1 
ATOM   1751  O  O   . ILE A 1 241 ? 12.200  27.789  33.441  1.00 24.42  ? 241 ILE A O   1 
ATOM   1752  C  CB  . ILE A 1 241 ? 9.557   29.886  32.929  1.00 23.23  ? 241 ILE A CB  1 
ATOM   1753  C  CG1 . ILE A 1 241 ? 10.396  30.150  31.713  1.00 25.39  ? 241 ILE A CG1 1 
ATOM   1754  C  CG2 . ILE A 1 241 ? 8.905   31.171  33.429  1.00 23.99  ? 241 ILE A CG2 1 
ATOM   1755  C  CD1 . ILE A 1 241 ? 9.583   30.668  30.543  1.00 27.97  ? 241 ILE A CD1 1 
ATOM   1756  N  N   . LEU A 1 242 ? 10.165  26.933  33.250  1.00 21.10  ? 242 LEU A N   1 
ATOM   1757  C  CA  . LEU A 1 242 ? 10.654  25.695  32.695  1.00 20.99  ? 242 LEU A CA  1 
ATOM   1758  C  C   . LEU A 1 242 ? 10.146  25.575  31.278  1.00 19.80  ? 242 LEU A C   1 
ATOM   1759  O  O   . LEU A 1 242 ? 8.946   25.550  31.094  1.00 22.89  ? 242 LEU A O   1 
ATOM   1760  C  CB  . LEU A 1 242 ? 10.116  24.537  33.517  1.00 21.99  ? 242 LEU A CB  1 
ATOM   1761  C  CG  . LEU A 1 242 ? 10.597  23.159  33.066  1.00 22.22  ? 242 LEU A CG  1 
ATOM   1762  C  CD1 . LEU A 1 242 ? 12.079  23.015  33.261  1.00 24.98  ? 242 LEU A CD1 1 
ATOM   1763  C  CD2 . LEU A 1 242 ? 9.874   22.088  33.886  1.00 25.00  ? 242 LEU A CD2 1 
ATOM   1764  N  N   . ARG A 1 243 ? 11.048  25.474  30.314  1.00 17.58  ? 243 ARG A N   1 
ATOM   1765  C  CA  . ARG A 1 243 ? 10.710  25.444  28.910  1.00 19.22  ? 243 ARG A CA  1 
ATOM   1766  C  C   . ARG A 1 243 ? 10.970  24.059  28.332  1.00 20.46  ? 243 ARG A C   1 
ATOM   1767  O  O   . ARG A 1 243 ? 11.844  23.358  28.801  1.00 21.16  ? 243 ARG A O   1 
ATOM   1768  C  CB  . ARG A 1 243 ? 11.597  26.419  28.136  1.00 21.38  ? 243 ARG A CB  1 
ATOM   1769  C  CG  . ARG A 1 243 ? 11.345  27.869  28.505  1.00 21.04  ? 243 ARG A CG  1 
ATOM   1770  C  CD  . ARG A 1 243 ? 12.416  28.767  27.930  1.00 23.82  ? 243 ARG A CD  1 
ATOM   1771  N  NE  . ARG A 1 243 ? 13.649  28.557  28.679  1.00 24.64  ? 243 ARG A NE  1 
ATOM   1772  C  CZ  . ARG A 1 243 ? 14.791  28.164  28.139  1.00 28.90  ? 243 ARG A CZ  1 
ATOM   1773  N  NH1 . ARG A 1 243 ? 14.918  28.064  26.820  1.00 30.05  ? 243 ARG A NH1 1 
ATOM   1774  N  NH2 . ARG A 1 243 ? 15.811  27.907  28.941  1.00 31.20  ? 243 ARG A NH2 1 
ATOM   1775  N  N   . ASP A 1 244 ? 10.235  23.667  27.295  1.00 20.80  ? 244 ASP A N   1 
ATOM   1776  C  CA  . ASP A 1 244 ? 10.561  22.464  26.561  1.00 23.45  ? 244 ASP A CA  1 
ATOM   1777  C  C   . ASP A 1 244 ? 10.264  22.701  25.091  1.00 21.74  ? 244 ASP A C   1 
ATOM   1778  O  O   . ASP A 1 244 ? 9.507   21.952  24.494  1.00 22.90  ? 244 ASP A O   1 
ATOM   1779  C  CB  . ASP A 1 244 ? 9.869   21.267  27.184  1.00 24.45  ? 244 ASP A CB  1 
ATOM   1780  C  CG  . ASP A 1 244 ? 10.524  19.938  26.850  1.00 28.79  ? 244 ASP A CG  1 
ATOM   1781  O  OD1 . ASP A 1 244 ? 11.547  19.942  26.132  1.00 32.40  ? 244 ASP A OD1 1 
ATOM   1782  O  OD2 . ASP A 1 244 ? 9.973   18.923  27.265  1.00 32.90  ? 244 ASP A OD2 1 
ATOM   1783  N  N   . ASN A 1 245 ? 10.934  23.709  24.523  1.00 21.99  ? 245 ASN A N   1 
ATOM   1784  C  CA  . ASN A 1 245 ? 10.785  24.041  23.112  1.00 23.66  ? 245 ASN A CA  1 
ATOM   1785  C  C   . ASN A 1 245 ? 11.108  22.829  22.232  1.00 23.97  ? 245 ASN A C   1 
ATOM   1786  O  O   . ASN A 1 245 ? 12.095  22.114  22.476  1.00 25.30  ? 245 ASN A O   1 
ATOM   1787  C  CB  . ASN A 1 245 ? 11.708  25.191  22.712  1.00 24.64  ? 245 ASN A CB  1 
ATOM   1788  C  CG  . ASN A 1 245 ? 11.427  26.410  23.556  1.00 28.35  ? 245 ASN A CG  1 
ATOM   1789  O  OD1 . ASN A 1 245 ? 10.411  26.464  24.270  1.00 32.27  ? 245 ASN A OD1 1 
ATOM   1790  N  ND2 . ASN A 1 245 ? 12.306  27.403  23.497  1.00 33.28  ? 245 ASN A ND2 1 
ATOM   1791  N  N   . MET A 1 246 ? 10.300  22.661  21.181  1.00 21.22  ? 246 MET A N   1 
ATOM   1792  C  CA  . MET A 1 246 ? 10.513  21.600  20.209  1.00 22.52  ? 246 MET A CA  1 
ATOM   1793  C  C   . MET A 1 246 ? 10.492  22.175  18.798  1.00 22.27  ? 246 MET A C   1 
ATOM   1794  O  O   . MET A 1 246 ? 9.558   22.865  18.406  1.00 20.76  ? 246 MET A O   1 
ATOM   1795  C  CB  . MET A 1 246 ? 9.432   20.525  20.279  1.00 24.71  ? 246 MET A CB  1 
ATOM   1796  C  CG  . MET A 1 246 ? 9.409   19.774  21.596  1.00 28.26  ? 246 MET A CG  1 
ATOM   1797  S  SD  . MET A 1 246 ? 10.900  18.785  21.811  1.00 27.86  ? 246 MET A SD  1 
ATOM   1798  C  CE  . MET A 1 246 ? 10.469  17.443  20.701  1.00 29.58  ? 246 MET A CE  1 
ATOM   1799  N  N   . PRO A 1 247 ? 11.519  21.873  17.984  1.00 22.82  ? 247 PRO A N   1 
ATOM   1800  C  CA  . PRO A 1 247 ? 11.467  22.075  16.547  1.00 22.34  ? 247 PRO A CA  1 
ATOM   1801  C  C   . PRO A 1 247 ? 10.352  21.270  15.874  1.00 19.40  ? 247 PRO A C   1 
ATOM   1802  O  O   . PRO A 1 247 ? 10.015  20.153  16.291  1.00 17.38  ? 247 PRO A O   1 
ATOM   1803  C  CB  . PRO A 1 247 ? 12.806  21.581  16.030  1.00 23.06  ? 247 PRO A CB  1 
ATOM   1804  C  CG  . PRO A 1 247 ? 13.654  21.434  17.225  1.00 24.67  ? 247 PRO A CG  1 
ATOM   1805  C  CD  . PRO A 1 247 ? 12.747  21.218  18.401  1.00 24.62  ? 247 PRO A CD  1 
ATOM   1806  N  N   . PHE A 1 248 ? 9.880   21.829  14.764  1.00 16.64  ? 248 PHE A N   1 
ATOM   1807  C  CA  . PHE A 1 248 ? 8.949   21.131  13.898  1.00 18.58  ? 248 PHE A CA  1 
ATOM   1808  C  C   . PHE A 1 248 ? 9.118   21.761  12.523  1.00 19.93  ? 248 PHE A C   1 
ATOM   1809  O  O   . PHE A 1 248 ? 9.722   22.836  12.363  1.00 18.02  ? 248 PHE A O   1 
ATOM   1810  C  CB  . PHE A 1 248 ? 7.490   21.250  14.370  1.00 18.22  ? 248 PHE A CB  1 
ATOM   1811  C  CG  . PHE A 1 248 ? 6.966   22.685  14.270  1.00 17.76  ? 248 PHE A CG  1 
ATOM   1812  C  CD1 . PHE A 1 248 ? 7.171   23.625  15.291  1.00 19.10  ? 248 PHE A CD1 1 
ATOM   1813  C  CD2 . PHE A 1 248 ? 6.297   23.100  13.136  1.00 17.37  ? 248 PHE A CD2 1 
ATOM   1814  C  CE1 . PHE A 1 248 ? 6.721   24.935  15.153  1.00 18.15  ? 248 PHE A CE1 1 
ATOM   1815  C  CE2 . PHE A 1 248 ? 5.882   24.412  13.005  1.00 18.97  ? 248 PHE A CE2 1 
ATOM   1816  C  CZ  . PHE A 1 248 ? 6.087   25.330  14.003  1.00 16.91  ? 248 PHE A CZ  1 
ATOM   1817  N  N   . GLY A 1 249 ? 8.566   21.100  11.515  1.00 22.18  ? 249 GLY A N   1 
ATOM   1818  C  CA  . GLY A 1 249 ? 8.566   21.757  10.232  1.00 24.82  ? 249 GLY A CA  1 
ATOM   1819  C  C   . GLY A 1 249 ? 8.106   20.862  9.096   1.00 24.42  ? 249 GLY A C   1 
ATOM   1820  O  O   . GLY A 1 249 ? 7.794   19.681  9.263   1.00 19.24  ? 249 GLY A O   1 
ATOM   1821  N  N   . SER A 1 250 ? 8.158   21.502  7.926   1.00 25.75  ? 250 SER A N   1 
ATOM   1822  C  CA  . SER A 1 250 ? 7.844   20.870  6.677   1.00 27.19  ? 250 SER A CA  1 
ATOM   1823  C  C   . SER A 1 250 ? 8.773   21.474  5.620   1.00 29.95  ? 250 SER A C   1 
ATOM   1824  O  O   . SER A 1 250 ? 8.829   22.683  5.429   1.00 28.66  ? 250 SER A O   1 
ATOM   1825  C  CB  . SER A 1 250 ? 6.386   21.022  6.403   1.00 26.65  ? 250 SER A CB  1 
ATOM   1826  O  OG  . SER A 1 250 ? 6.146   21.139  5.000   1.00 35.09  ? 250 SER A OG  1 
ATOM   1827  N  N   . VAL A 1 251 ? 9.552   20.630  4.941   1.00 31.63  ? 251 VAL A N   1 
ATOM   1828  C  CA  . VAL A 1 251 ? 10.568  21.151  4.043   1.00 30.81  ? 251 VAL A CA  1 
ATOM   1829  C  C   . VAL A 1 251 ? 9.907   21.601  2.727   1.00 26.52  ? 251 VAL A C   1 
ATOM   1830  O  O   . VAL A 1 251 ? 10.295  22.613  2.148   1.00 22.73  ? 251 VAL A O   1 
ATOM   1831  C  CB  . VAL A 1 251 ? 11.763  20.166  3.979   1.00 38.44  ? 251 VAL A CB  1 
ATOM   1832  C  CG1 . VAL A 1 251 ? 11.422  18.730  4.336   1.00 45.49  ? 251 VAL A CG1 1 
ATOM   1833  C  CG2 . VAL A 1 251 ? 12.519  20.176  2.672   1.00 40.48  ? 251 VAL A CG2 1 
ATOM   1834  N  N   . GLY A 1 252 ? 8.839   20.920  2.318   1.00 25.83  ? 252 GLY A N   1 
ATOM   1835  C  CA  . GLY A 1 252 ? 8.069   21.260  1.134   1.00 27.98  ? 252 GLY A CA  1 
ATOM   1836  C  C   . GLY A 1 252 ? 7.460   22.663  1.206   1.00 30.32  ? 252 GLY A C   1 
ATOM   1837  O  O   . GLY A 1 252 ? 7.414   23.368  0.227   1.00 32.77  ? 252 GLY A O   1 
ATOM   1838  N  N   . ARG A 1 253 ? 7.018   23.088  2.383   1.00 31.56  ? 253 ARG A N   1 
ATOM   1839  C  CA  . ARG A 1 253 ? 6.394   24.378  2.561   1.00 28.26  ? 253 ARG A CA  1 
ATOM   1840  C  C   . ARG A 1 253 ? 7.367   25.421  3.057   1.00 26.00  ? 253 ARG A C   1 
ATOM   1841  O  O   . ARG A 1 253 ? 6.940   26.522  3.324   1.00 27.54  ? 253 ARG A O   1 
ATOM   1842  C  CB  . ARG A 1 253 ? 5.225   24.197  3.525   1.00 32.48  ? 253 ARG A CB  1 
ATOM   1843  C  CG  . ARG A 1 253 ? 4.151   23.362  2.834   1.00 43.39  ? 253 ARG A CG  1 
ATOM   1844  C  CD  . ARG A 1 253 ? 2.752   23.863  3.178   1.00 53.96  ? 253 ARG A CD  1 
ATOM   1845  N  NE  . ARG A 1 253 ? 2.783   23.961  4.643   1.00 82.75  ? 253 ARG A NE  1 
ATOM   1846  C  CZ  . ARG A 1 253 ? 2.941   22.949  5.538   1.00 86.28  ? 253 ARG A CZ  1 
ATOM   1847  N  NH1 . ARG A 1 253 ? 3.334   23.229  6.766   1.00 83.04  ? 253 ARG A NH1 1 
ATOM   1848  N  NH2 . ARG A 1 253 ? 2.774   21.667  5.220   1.00 73.79  ? 253 ARG A NH2 1 
ATOM   1849  N  N   . GLU A 1 254 ? 8.651   25.085  3.155   1.00 26.96  ? 254 GLU A N   1 
ATOM   1850  C  CA  . GLU A 1 254 ? 9.661   25.948  3.766   1.00 28.50  ? 254 GLU A CA  1 
ATOM   1851  C  C   . GLU A 1 254 ? 9.208   26.452  5.131   1.00 27.48  ? 254 GLU A C   1 
ATOM   1852  O  O   . GLU A 1 254 ? 9.396   27.619  5.441   1.00 27.79  ? 254 GLU A O   1 
ATOM   1853  C  CB  . GLU A 1 254 ? 10.019  27.139  2.884   1.00 31.03  ? 254 GLU A CB  1 
ATOM   1854  C  CG  . GLU A 1 254 ? 10.655  26.689  1.576   1.00 39.75  ? 254 GLU A CG  1 
ATOM   1855  C  CD  . GLU A 1 254 ? 10.901  27.832  0.573   1.00 46.74  ? 254 GLU A CD  1 
ATOM   1856  O  OE1 . GLU A 1 254 ? 11.279  28.968  1.036   1.00 41.85  ? 254 GLU A OE1 1 
ATOM   1857  O  OE2 . GLU A 1 254 ? 10.736  27.576  -0.662  1.00 39.45  ? 254 GLU A OE2 1 
ATOM   1858  N  N   . GLU A 1 255 ? 8.642   25.569  5.956   1.00 26.03  ? 255 GLU A N   1 
ATOM   1859  C  CA  . GLU A 1 255 ? 8.219   25.915  7.296   1.00 25.76  ? 255 GLU A CA  1 
ATOM   1860  C  C   . GLU A 1 255 ? 9.198   25.325  8.315   1.00 25.56  ? 255 GLU A C   1 
ATOM   1861  O  O   . GLU A 1 255 ? 9.411   24.107  8.402   1.00 23.02  ? 255 GLU A O   1 
ATOM   1862  C  CB  . GLU A 1 255 ? 6.843   25.283  7.397   1.00 29.47  ? 255 GLU A CB  1 
ATOM   1863  C  CG  . GLU A 1 255 ? 6.062   25.758  8.604   1.00 39.87  ? 255 GLU A CG  1 
ATOM   1864  C  CD  . GLU A 1 255 ? 4.714   25.088  8.529   1.00 49.48  ? 255 GLU A CD  1 
ATOM   1865  O  OE1 . GLU A 1 255 ? 4.085   25.316  7.451   1.00 44.76  ? 255 GLU A OE1 1 
ATOM   1866  O  OE2 . GLU A 1 255 ? 4.403   24.306  9.480   1.00 50.12  ? 255 GLU A OE2 1 
ATOM   1867  N  N   . PHE A 1 256 ? 9.861   26.224  9.044   1.00 24.65  ? 256 PHE A N   1 
ATOM   1868  C  CA  . PHE A 1 256 ? 10.798  25.834  10.069  1.00 25.66  ? 256 PHE A CA  1 
ATOM   1869  C  C   . PHE A 1 256 ? 10.369  26.524  11.349  1.00 23.11  ? 256 PHE A C   1 
ATOM   1870  O  O   . PHE A 1 256 ? 10.313  27.746  11.372  1.00 19.69  ? 256 PHE A O   1 
ATOM   1871  C  CB  . PHE A 1 256 ? 12.164  26.301  9.567   1.00 26.59  ? 256 PHE A CB  1 
ATOM   1872  C  CG  . PHE A 1 256 ? 12.586  25.609  8.288   1.00 29.09  ? 256 PHE A CG  1 
ATOM   1873  C  CD1 . PHE A 1 256 ? 13.031  24.295  8.289   1.00 31.31  ? 256 PHE A CD1 1 
ATOM   1874  C  CD2 . PHE A 1 256 ? 12.549  26.289  7.096   1.00 28.74  ? 256 PHE A CD2 1 
ATOM   1875  C  CE1 . PHE A 1 256 ? 13.345  23.663  7.113   1.00 33.66  ? 256 PHE A CE1 1 
ATOM   1876  C  CE2 . PHE A 1 256 ? 12.923  25.665  5.924   1.00 30.08  ? 256 PHE A CE2 1 
ATOM   1877  C  CZ  . PHE A 1 256 ? 13.311  24.353  5.936   1.00 32.53  ? 256 PHE A CZ  1 
ATOM   1878  N  N   . GLY A 1 257 ? 10.096  25.752  12.398  1.00 22.96  ? 257 GLY A N   1 
ATOM   1879  C  CA  . GLY A 1 257 ? 9.476   26.365  13.545  1.00 22.00  ? 257 GLY A CA  1 
ATOM   1880  C  C   . GLY A 1 257 ? 10.085  25.931  14.868  1.00 22.97  ? 257 GLY A C   1 
ATOM   1881  O  O   . GLY A 1 257 ? 10.787  24.938  14.949  1.00 21.63  ? 257 GLY A O   1 
ATOM   1882  N  N   . THR A 1 258 ? 9.759   26.717  15.898  1.00 26.62  ? 258 THR A N   1 
ATOM   1883  C  CA  . THR A 1 258 ? 10.000  26.346  17.282  1.00 23.90  ? 258 THR A CA  1 
ATOM   1884  C  C   . THR A 1 258 ? 8.642   26.409  17.958  1.00 19.27  ? 258 THR A C   1 
ATOM   1885  O  O   . THR A 1 258 ? 7.968   27.434  17.866  1.00 18.43  ? 258 THR A O   1 
ATOM   1886  C  CB  . THR A 1 258 ? 11.036  27.295  17.907  1.00 25.78  ? 258 THR A CB  1 
ATOM   1887  O  OG1 . THR A 1 258 ? 12.336  27.059  17.334  1.00 26.67  ? 258 THR A OG1 1 
ATOM   1888  C  CG2 . THR A 1 258 ? 11.048  27.169  19.426  1.00 25.77  ? 258 THR A CG2 1 
ATOM   1889  N  N   . TYR A 1 259 ? 8.212   25.313  18.569  1.00 18.20  ? 259 TYR A N   1 
ATOM   1890  C  CA  . TYR A 1 259 ? 7.009   25.336  19.396  1.00 19.11  ? 259 TYR A CA  1 
ATOM   1891  C  C   . TYR A 1 259 ? 7.444   25.647  20.834  1.00 18.92  ? 259 TYR A C   1 
ATOM   1892  O  O   . TYR A 1 259 ? 8.103   24.863  21.475  1.00 18.20  ? 259 TYR A O   1 
ATOM   1893  C  CB  . TYR A 1 259 ? 6.179   24.056  19.291  1.00 20.25  ? 259 TYR A CB  1 
ATOM   1894  C  CG  . TYR A 1 259 ? 4.719   24.181  19.721  1.00 23.46  ? 259 TYR A CG  1 
ATOM   1895  C  CD1 . TYR A 1 259 ? 4.358   24.100  21.057  1.00 25.89  ? 259 TYR A CD1 1 
ATOM   1896  C  CD2 . TYR A 1 259 ? 3.696   24.367  18.792  1.00 24.40  ? 259 TYR A CD2 1 
ATOM   1897  C  CE1 . TYR A 1 259 ? 3.040   24.221  21.463  1.00 26.92  ? 259 TYR A CE1 1 
ATOM   1898  C  CE2 . TYR A 1 259 ? 2.375   24.450  19.183  1.00 24.88  ? 259 TYR A CE2 1 
ATOM   1899  C  CZ  . TYR A 1 259 ? 2.046   24.395  20.521  1.00 26.79  ? 259 TYR A CZ  1 
ATOM   1900  O  OH  . TYR A 1 259 ? 0.758   24.506  20.941  1.00 29.85  ? 259 TYR A OH  1 
ATOM   1901  N  N   . PHE A 1 260 ? 7.100   26.840  21.313  1.00 19.94  ? 260 PHE A N   1 
ATOM   1902  C  CA  . PHE A 1 260 ? 7.452   27.283  22.641  1.00 20.65  ? 260 PHE A CA  1 
ATOM   1903  C  C   . PHE A 1 260 ? 6.401   26.805  23.640  1.00 21.62  ? 260 PHE A C   1 
ATOM   1904  O  O   . PHE A 1 260 ? 5.206   27.012  23.432  1.00 20.54  ? 260 PHE A O   1 
ATOM   1905  C  CB  . PHE A 1 260 ? 7.501   28.799  22.666  1.00 20.89  ? 260 PHE A CB  1 
ATOM   1906  C  CG  . PHE A 1 260 ? 7.623   29.299  24.083  1.00 24.07  ? 260 PHE A CG  1 
ATOM   1907  C  CD1 . PHE A 1 260 ? 8.855   29.317  24.721  1.00 31.40  ? 260 PHE A CD1 1 
ATOM   1908  C  CD2 . PHE A 1 260 ? 6.522   29.737  24.776  1.00 27.54  ? 260 PHE A CD2 1 
ATOM   1909  C  CE1 . PHE A 1 260 ? 8.971   29.770  26.029  1.00 31.53  ? 260 PHE A CE1 1 
ATOM   1910  C  CE2 . PHE A 1 260 ? 6.640   30.186  26.081  1.00 31.91  ? 260 PHE A CE2 1 
ATOM   1911  C  CZ  . PHE A 1 260 ? 7.858   30.208  26.702  1.00 29.98  ? 260 PHE A CZ  1 
ATOM   1912  N  N   . ILE A 1 261 ? 6.863   26.181  24.734  1.00 20.46  ? 261 ILE A N   1 
ATOM   1913  C  CA  . ILE A 1 261 ? 6.006   25.932  25.872  1.00 21.66  ? 261 ILE A CA  1 
ATOM   1914  C  C   . ILE A 1 261 ? 6.801   26.292  27.121  1.00 24.08  ? 261 ILE A C   1 
ATOM   1915  O  O   . ILE A 1 261 ? 7.923   25.866  27.274  1.00 23.73  ? 261 ILE A O   1 
ATOM   1916  C  CB  . ILE A 1 261 ? 5.407   24.507  25.895  1.00 20.95  ? 261 ILE A CB  1 
ATOM   1917  C  CG1 . ILE A 1 261 ? 4.415   24.343  26.999  1.00 21.91  ? 261 ILE A CG1 1 
ATOM   1918  C  CG2 . ILE A 1 261 ? 6.474   23.433  26.027  1.00 22.41  ? 261 ILE A CG2 1 
ATOM   1919  C  CD1 . ILE A 1 261 ? 3.544   23.099  26.862  1.00 22.81  ? 261 ILE A CD1 1 
ATOM   1920  N  N   . GLY A 1 262 ? 6.232   27.161  27.960  1.00 25.04  ? 262 GLY A N   1 
ATOM   1921  C  CA  . GLY A 1 262 ? 6.828   27.596  29.208  1.00 22.44  ? 262 GLY A CA  1 
ATOM   1922  C  C   . GLY A 1 262 ? 5.864   27.373  30.376  1.00 22.14  ? 262 GLY A C   1 
ATOM   1923  O  O   . GLY A 1 262 ? 4.733   27.849  30.377  1.00 26.49  ? 262 GLY A O   1 
ATOM   1924  N  N   . TYR A 1 263 ? 6.333   26.644  31.387  1.00 21.43  ? 263 TYR A N   1 
ATOM   1925  C  CA  . TYR A 1 263 ? 5.596   26.429  32.608  1.00 20.46  ? 263 TYR A CA  1 
ATOM   1926  C  C   . TYR A 1 263 ? 6.136   27.308  33.734  1.00 20.31  ? 263 TYR A C   1 
ATOM   1927  O  O   . TYR A 1 263 ? 7.338   27.458  33.860  1.00 19.02  ? 263 TYR A O   1 
ATOM   1928  C  CB  . TYR A 1 263 ? 5.734   24.971  32.999  1.00 20.55  ? 263 TYR A CB  1 
ATOM   1929  C  CG  . TYR A 1 263 ? 5.024   23.949  32.131  1.00 20.96  ? 263 TYR A CG  1 
ATOM   1930  C  CD1 . TYR A 1 263 ? 3.725   23.549  32.420  1.00 22.22  ? 263 TYR A CD1 1 
ATOM   1931  C  CD2 . TYR A 1 263 ? 5.671   23.324  31.083  1.00 21.27  ? 263 TYR A CD2 1 
ATOM   1932  C  CE1 . TYR A 1 263 ? 3.090   22.558  31.675  1.00 22.88  ? 263 TYR A CE1 1 
ATOM   1933  C  CE2 . TYR A 1 263 ? 5.037   22.358  30.320  1.00 20.54  ? 263 TYR A CE2 1 
ATOM   1934  C  CZ  . TYR A 1 263 ? 3.752   21.948  30.618  1.00 20.56  ? 263 TYR A CZ  1 
ATOM   1935  O  OH  . TYR A 1 263 ? 3.108   21.006  29.865  1.00 19.13  ? 263 TYR A OH  1 
ATOM   1936  N  N   . ALA A 1 264 ? 5.222   27.790  34.590  1.00 21.12  ? 264 ALA A N   1 
ATOM   1937  C  CA  . ALA A 1 264 ? 5.541   28.635  35.730  1.00 20.00  ? 264 ALA A CA  1 
ATOM   1938  C  C   . ALA A 1 264 ? 4.428   28.549  36.760  1.00 22.64  ? 264 ALA A C   1 
ATOM   1939  O  O   . ALA A 1 264 ? 3.293   28.271  36.395  1.00 22.47  ? 264 ALA A O   1 
ATOM   1940  C  CB  . ALA A 1 264 ? 5.668   30.043  35.254  1.00 20.87  ? 264 ALA A CB  1 
ATOM   1941  N  N   . ARG A 1 265 ? 4.753   28.826  38.036  1.00 26.57  ? 265 ARG A N   1 
ATOM   1942  C  CA  . ARG A 1 265 ? 3.821   28.731  39.170  1.00 25.41  ? 265 ARG A CA  1 
ATOM   1943  C  C   . ARG A 1 265 ? 2.771   29.840  39.100  1.00 24.61  ? 265 ARG A C   1 
ATOM   1944  O  O   . ARG A 1 265 ? 1.713   29.717  39.706  1.00 21.56  ? 265 ARG A O   1 
ATOM   1945  C  CB  . ARG A 1 265 ? 4.504   28.721  40.551  1.00 27.10  ? 265 ARG A CB  1 
ATOM   1946  C  CG  . ARG A 1 265 ? 5.044   30.099  40.952  1.00 35.27  ? 265 ARG A CG  1 
ATOM   1947  C  CD  . ARG A 1 265 ? 5.833   30.305  42.265  1.00 45.43  ? 265 ARG A CD  1 
ATOM   1948  N  NE  . ARG A 1 265 ? 5.077   29.924  43.463  1.00 60.82  ? 265 ARG A NE  1 
ATOM   1949  C  CZ  . ARG A 1 265 ? 5.306   28.877  44.308  1.00 76.58  ? 265 ARG A CZ  1 
ATOM   1950  N  NH1 . ARG A 1 265 ? 6.492   28.308  44.404  1.00 86.94  ? 265 ARG A NH1 1 
ATOM   1951  N  NH2 . ARG A 1 265 ? 4.357   28.461  45.132  1.00 75.98  ? 265 ARG A NH2 1 
ATOM   1952  N  N   . THR A 1 266 ? 3.073   30.917  38.369  1.00 24.25  ? 266 THR A N   1 
ATOM   1953  C  CA  . THR A 1 266 ? 2.121   31.997  38.110  1.00 27.59  ? 266 THR A CA  1 
ATOM   1954  C  C   . THR A 1 266 ? 2.388   32.524  36.702  1.00 25.81  ? 266 THR A C   1 
ATOM   1955  O  O   . THR A 1 266 ? 3.526   32.632  36.272  1.00 25.75  ? 266 THR A O   1 
ATOM   1956  C  CB  . THR A 1 266 ? 2.252   33.123  39.151  1.00 27.15  ? 266 THR A CB  1 
ATOM   1957  O  OG1 . THR A 1 266 ? 1.569   34.247  38.627  1.00 27.41  ? 266 THR A OG1 1 
ATOM   1958  C  CG2 . THR A 1 266 ? 3.668   33.615  39.347  1.00 24.96  ? 266 THR A CG2 1 
ATOM   1959  N  N   . PRO A 1 267 ? 1.365   32.927  35.937  1.00 24.33  ? 267 PRO A N   1 
ATOM   1960  C  CA  . PRO A 1 267 ? 1.619   33.474  34.610  1.00 25.04  ? 267 PRO A CA  1 
ATOM   1961  C  C   . PRO A 1 267 ? 2.291   34.838  34.638  1.00 25.01  ? 267 PRO A C   1 
ATOM   1962  O  O   . PRO A 1 267 ? 2.833   35.249  33.622  1.00 27.14  ? 267 PRO A O   1 
ATOM   1963  C  CB  . PRO A 1 267 ? 0.268   33.480  33.940  1.00 24.30  ? 267 PRO A CB  1 
ATOM   1964  C  CG  . PRO A 1 267 ? -0.721  33.488  35.087  1.00 26.33  ? 267 PRO A CG  1 
ATOM   1965  C  CD  . PRO A 1 267 ? -0.053  32.827  36.263  1.00 26.10  ? 267 PRO A CD  1 
ATOM   1966  N  N   . GLU A 1 268 ? 2.364   35.480  35.811  1.00 24.52  ? 268 GLU A N   1 
ATOM   1967  C  CA  . GLU A 1 268 ? 2.999   36.787  35.918  1.00 26.28  ? 268 GLU A CA  1 
ATOM   1968  C  C   . GLU A 1 268 ? 4.447   36.706  35.450  1.00 21.88  ? 268 GLU A C   1 
ATOM   1969  O  O   . GLU A 1 268 ? 4.950   37.578  34.749  1.00 19.39  ? 268 GLU A O   1 
ATOM   1970  C  CB  . GLU A 1 268 ? 2.785   37.323  37.327  1.00 31.44  ? 268 GLU A CB  1 
ATOM   1971  C  CG  . GLU A 1 268 ? 3.591   38.582  37.567  1.00 40.58  ? 268 GLU A CG  1 
ATOM   1972  C  CD  . GLU A 1 268 ? 2.674   39.470  38.362  1.00 51.71  ? 268 GLU A CD  1 
ATOM   1973  O  OE1 . GLU A 1 268 ? 2.606   39.341  39.617  1.00 57.69  ? 268 GLU A OE1 1 
ATOM   1974  O  OE2 . GLU A 1 268 ? 1.929   40.182  37.644  1.00 61.89  ? 268 GLU A OE2 1 
ATOM   1975  N  N   . VAL A 1 269 ? 5.115   35.601  35.743  1.00 24.10  ? 269 VAL A N   1 
ATOM   1976  C  CA  . VAL A 1 269 ? 6.524   35.471  35.404  1.00 27.72  ? 269 VAL A CA  1 
ATOM   1977  C  C   . VAL A 1 269 ? 6.679   35.392  33.882  1.00 25.43  ? 269 VAL A C   1 
ATOM   1978  O  O   . VAL A 1 269 ? 7.461   36.154  33.284  1.00 22.34  ? 269 VAL A O   1 
ATOM   1979  C  CB  . VAL A 1 269 ? 7.158   34.238  36.080  1.00 27.42  ? 269 VAL A CB  1 
ATOM   1980  C  CG1 . VAL A 1 269 ? 8.620   34.086  35.696  1.00 31.65  ? 269 VAL A CG1 1 
ATOM   1981  C  CG2 . VAL A 1 269 ? 7.071   34.349  37.579  1.00 28.86  ? 269 VAL A CG2 1 
ATOM   1982  N  N   . THR A 1 270 ? 5.943   34.429  33.295  1.00 23.36  ? 270 THR A N   1 
ATOM   1983  C  CA  . THR A 1 270 ? 6.008   34.188  31.864  1.00 21.49  ? 270 THR A CA  1 
ATOM   1984  C  C   . THR A 1 270 ? 5.611   35.459  31.129  1.00 20.73  ? 270 THR A C   1 
ATOM   1985  O  O   . THR A 1 270 ? 6.220   35.805  30.127  1.00 21.84  ? 270 THR A O   1 
ATOM   1986  C  CB  . THR A 1 270 ? 5.112   33.018  31.475  1.00 21.55  ? 270 THR A CB  1 
ATOM   1987  O  OG1 . THR A 1 270 ? 5.409   31.822  32.177  1.00 25.11  ? 270 THR A OG1 1 
ATOM   1988  C  CG2 . THR A 1 270 ? 5.351   32.580  30.054  1.00 21.84  ? 270 THR A CG2 1 
ATOM   1989  N  N   . GLU A 1 271 ? 4.566   36.150  31.623  1.00 22.88  ? 271 GLU A N   1 
ATOM   1990  C  CA  . GLU A 1 271 ? 4.019   37.311  30.948  1.00 22.31  ? 271 GLU A CA  1 
ATOM   1991  C  C   . GLU A 1 271 ? 4.978   38.488  31.044  1.00 22.10  ? 271 GLU A C   1 
ATOM   1992  O  O   . GLU A 1 271 ? 5.024   39.292  30.133  1.00 23.00  ? 271 GLU A O   1 
ATOM   1993  C  CB  . GLU A 1 271 ? 2.651   37.595  31.526  1.00 23.50  ? 271 GLU A CB  1 
ATOM   1994  C  CG  . GLU A 1 271 ? 1.541   36.789  30.873  1.00 27.43  ? 271 GLU A CG  1 
ATOM   1995  C  CD  . GLU A 1 271 ? 0.196   36.895  31.586  1.00 31.59  ? 271 GLU A CD  1 
ATOM   1996  O  OE1 . GLU A 1 271 ? 0.120   37.602  32.590  1.00 39.37  ? 271 GLU A OE1 1 
ATOM   1997  O  OE2 . GLU A 1 271 ? -0.757  36.210  31.212  1.00 35.02  ? 271 GLU A OE2 1 
ATOM   1998  N  N   . THR A 1 272 ? 5.764   38.583  32.112  1.00 23.37  ? 272 THR A N   1 
ATOM   1999  C  CA  . THR A 1 272 ? 6.747   39.652  32.202  1.00 24.88  ? 272 THR A CA  1 
ATOM   2000  C  C   . THR A 1 272 ? 7.785   39.480  31.090  1.00 27.16  ? 272 THR A C   1 
ATOM   2001  O  O   . THR A 1 272 ? 8.161   40.449  30.407  1.00 25.26  ? 272 THR A O   1 
ATOM   2002  C  CB  . THR A 1 272 ? 7.425   39.628  33.575  1.00 25.11  ? 272 THR A CB  1 
ATOM   2003  O  OG1 . THR A 1 272 ? 6.403   39.896  34.525  1.00 24.45  ? 272 THR A OG1 1 
ATOM   2004  C  CG2 . THR A 1 272 ? 8.542   40.645  33.716  1.00 21.82  ? 272 THR A CG2 1 
ATOM   2005  N  N   . MET A 1 273 ? 8.283   38.238  30.958  1.00 26.00  ? 273 MET A N   1 
ATOM   2006  C  CA  . MET A 1 273 ? 9.301   37.946  29.972  1.00 25.23  ? 273 MET A CA  1 
ATOM   2007  C  C   . MET A 1 273 ? 8.742   38.286  28.590  1.00 26.69  ? 273 MET A C   1 
ATOM   2008  O  O   . MET A 1 273 ? 9.429   38.867  27.747  1.00 29.65  ? 273 MET A O   1 
ATOM   2009  C  CB  . MET A 1 273 ? 9.692   36.468  30.039  1.00 27.22  ? 273 MET A CB  1 
ATOM   2010  C  CG  . MET A 1 273 ? 10.447  36.060  31.282  1.00 30.56  ? 273 MET A CG  1 
ATOM   2011  S  SD  . MET A 1 273 ? 10.660  34.272  31.381  1.00 31.95  ? 273 MET A SD  1 
ATOM   2012  C  CE  . MET A 1 273 ? 11.589  34.082  32.916  1.00 34.59  ? 273 MET A CE  1 
ATOM   2013  N  N   . LEU A 1 274 ? 7.470   37.937  28.359  1.00 23.86  ? 274 LEU A N   1 
ATOM   2014  C  CA  . LEU A 1 274 ? 6.858   38.204  27.082  1.00 24.41  ? 274 LEU A CA  1 
ATOM   2015  C  C   . LEU A 1 274 ? 6.783   39.702  26.779  1.00 27.95  ? 274 LEU A C   1 
ATOM   2016  O  O   . LEU A 1 274 ? 6.995   40.110  25.630  1.00 29.55  ? 274 LEU A O   1 
ATOM   2017  C  CB  . LEU A 1 274 ? 5.480   37.565  27.057  1.00 24.49  ? 274 LEU A CB  1 
ATOM   2018  C  CG  . LEU A 1 274 ? 5.427   36.090  26.667  1.00 24.64  ? 274 LEU A CG  1 
ATOM   2019  C  CD1 . LEU A 1 274 ? 4.030   35.468  26.881  1.00 23.59  ? 274 LEU A CD1 1 
ATOM   2020  C  CD2 . LEU A 1 274 ? 5.814   35.998  25.180  1.00 25.36  ? 274 LEU A CD2 1 
ATOM   2021  N  N   . GLU A 1 275 ? 6.431   40.511  27.781  1.00 29.99  ? 275 GLU A N   1 
ATOM   2022  C  CA  . GLU A 1 275 ? 6.319   41.951  27.585  1.00 31.56  ? 275 GLU A CA  1 
ATOM   2023  C  C   . GLU A 1 275 ? 7.680   42.537  27.269  1.00 27.53  ? 275 GLU A C   1 
ATOM   2024  O  O   . GLU A 1 275 ? 7.784   43.379  26.392  1.00 27.52  ? 275 GLU A O   1 
ATOM   2025  C  CB  . GLU A 1 275 ? 5.797   42.695  28.816  1.00 39.42  ? 275 GLU A CB  1 
ATOM   2026  C  CG  . GLU A 1 275 ? 4.307   42.467  29.069  1.00 43.20  ? 275 GLU A CG  1 
ATOM   2027  C  CD  . GLU A 1 275 ? 3.835   43.099  30.361  1.00 52.80  ? 275 GLU A CD  1 
ATOM   2028  O  OE1 . GLU A 1 275 ? 4.529   44.052  30.807  1.00 58.64  ? 275 GLU A OE1 1 
ATOM   2029  O  OE2 . GLU A 1 275 ? 2.793   42.662  30.886  1.00 51.55  ? 275 GLU A OE2 1 
ATOM   2030  N  N   . ARG A 1 276 ? 8.708   42.072  27.980  1.00 28.28  ? 276 ARG A N   1 
ATOM   2031  C  CA  . ARG A 1 276 ? 10.052  42.537  27.697  1.00 32.44  ? 276 ARG A CA  1 
ATOM   2032  C  C   . ARG A 1 276 ? 10.469  42.174  26.277  1.00 32.95  ? 276 ARG A C   1 
ATOM   2033  O  O   . ARG A 1 276 ? 11.170  42.952  25.633  1.00 28.64  ? 276 ARG A O   1 
ATOM   2034  C  CB  . ARG A 1 276 ? 11.066  41.960  28.682  1.00 32.31  ? 276 ARG A CB  1 
ATOM   2035  C  CG  . ARG A 1 276 ? 10.911  42.733  29.971  1.00 37.30  ? 276 ARG A CG  1 
ATOM   2036  C  CD  . ARG A 1 276 ? 11.235  41.947  31.200  1.00 39.14  ? 276 ARG A CD  1 
ATOM   2037  N  NE  . ARG A 1 276 ? 12.667  41.626  31.197  1.00 44.28  ? 276 ARG A NE  1 
ATOM   2038  C  CZ  . ARG A 1 276 ? 13.675  42.447  31.466  1.00 41.49  ? 276 ARG A CZ  1 
ATOM   2039  N  NH1 . ARG A 1 276 ? 13.450  43.689  31.831  1.00 44.21  ? 276 ARG A NH1 1 
ATOM   2040  N  NH2 . ARG A 1 276 ? 14.909  42.025  31.362  1.00 35.26  ? 276 ARG A NH2 1 
ATOM   2041  N  N   . MET A 1 277 ? 10.056  41.006  25.785  1.00 28.29  ? 277 MET A N   1 
ATOM   2042  C  CA  . MET A 1 277 ? 10.467  40.602  24.456  1.00 28.08  ? 277 MET A CA  1 
ATOM   2043  C  C   . MET A 1 277 ? 9.726   41.430  23.407  1.00 25.45  ? 277 MET A C   1 
ATOM   2044  O  O   . MET A 1 277 ? 10.326  41.886  22.446  1.00 33.08  ? 277 MET A O   1 
ATOM   2045  C  CB  . MET A 1 277 ? 10.203  39.110  24.207  1.00 28.04  ? 277 MET A CB  1 
ATOM   2046  C  CG  . MET A 1 277 ? 11.128  38.143  24.945  1.00 25.01  ? 277 MET A CG  1 
ATOM   2047  S  SD  . MET A 1 277 ? 10.477  36.465  24.765  1.00 24.63  ? 277 MET A SD  1 
ATOM   2048  C  CE  . MET A 1 277 ? 10.649  36.227  22.990  1.00 27.25  ? 277 MET A CE  1 
ATOM   2049  N  N   . PHE A 1 278 ? 8.429   41.627  23.579  1.00 24.05  ? 278 PHE A N   1 
ATOM   2050  C  CA  . PHE A 1 278 ? 7.603   42.180  22.511  1.00 27.64  ? 278 PHE A CA  1 
ATOM   2051  C  C   . PHE A 1 278 ? 7.579   43.708  22.545  1.00 27.10  ? 278 PHE A C   1 
ATOM   2052  O  O   . PHE A 1 278 ? 7.441   44.350  21.499  1.00 26.77  ? 278 PHE A O   1 
ATOM   2053  C  CB  . PHE A 1 278 ? 6.194   41.572  22.557  1.00 24.25  ? 278 PHE A CB  1 
ATOM   2054  C  CG  . PHE A 1 278 ? 6.152   40.237  21.831  1.00 21.89  ? 278 PHE A CG  1 
ATOM   2055  C  CD1 . PHE A 1 278 ? 6.480   39.054  22.476  1.00 20.37  ? 278 PHE A CD1 1 
ATOM   2056  C  CD2 . PHE A 1 278 ? 5.848   40.183  20.484  1.00 21.05  ? 278 PHE A CD2 1 
ATOM   2057  C  CE1 . PHE A 1 278 ? 6.489   37.855  21.796  1.00 19.53  ? 278 PHE A CE1 1 
ATOM   2058  C  CE2 . PHE A 1 278 ? 5.829   38.967  19.829  1.00 21.50  ? 278 PHE A CE2 1 
ATOM   2059  C  CZ  . PHE A 1 278 ? 6.186   37.819  20.481  1.00 20.02  ? 278 PHE A CZ  1 
ATOM   2060  N  N   . LEU A 1 279 ? 7.568   44.243  23.770  1.00 32.34  ? 279 LEU A N   1 
ATOM   2061  C  CA  . LEU A 1 279 ? 7.334   45.656  23.998  1.00 33.55  ? 279 LEU A CA  1 
ATOM   2062  C  C   . LEU A 1 279 ? 8.631   46.343  24.391  1.00 33.87  ? 279 LEU A C   1 
ATOM   2063  O  O   . LEU A 1 279 ? 8.734   47.553  24.283  1.00 41.96  ? 279 LEU A O   1 
ATOM   2064  C  CB  . LEU A 1 279 ? 6.287   45.890  25.078  1.00 33.87  ? 279 LEU A CB  1 
ATOM   2065  C  CG  . LEU A 1 279 ? 4.941   45.187  24.891  1.00 34.53  ? 279 LEU A CG  1 
ATOM   2066  C  CD1 . LEU A 1 279 ? 4.080   45.616  26.048  1.00 37.82  ? 279 LEU A CD1 1 
ATOM   2067  C  CD2 . LEU A 1 279 ? 4.213   45.402  23.614  1.00 31.96  ? 279 LEU A CD2 1 
ATOM   2068  N  N   . GLY A 1 280 ? 9.636   45.605  24.830  1.00 34.18  ? 280 GLY A N   1 
ATOM   2069  C  CA  . GLY A 1 280 ? 10.954  46.201  25.005  1.00 40.76  ? 280 GLY A CA  1 
ATOM   2070  C  C   . GLY A 1 280 ? 11.116  46.772  26.411  1.00 40.35  ? 280 GLY A C   1 
ATOM   2071  O  O   . GLY A 1 280 ? 10.201  46.629  27.209  1.00 40.13  ? 280 GLY A O   1 
ATOM   2072  N  N   . THR A 1 281 ? 12.297  47.355  26.670  1.00 41.26  ? 281 THR A N   1 
ATOM   2073  C  CA  . THR A 1 281 ? 12.643  48.002  27.918  1.00 42.66  ? 281 THR A CA  1 
ATOM   2074  C  C   . THR A 1 281 ? 13.124  49.416  27.627  1.00 47.93  ? 281 THR A C   1 
ATOM   2075  O  O   . THR A 1 281 ? 13.075  49.859  26.480  1.00 41.34  ? 281 THR A O   1 
ATOM   2076  C  CB  . THR A 1 281 ? 13.705  47.202  28.668  1.00 41.27  ? 281 THR A CB  1 
ATOM   2077  O  OG1 . THR A 1 281 ? 14.931  47.286  27.930  1.00 50.66  ? 281 THR A OG1 1 
ATOM   2078  C  CG2 . THR A 1 281 ? 13.181  45.810  28.964  1.00 40.77  ? 281 THR A CG2 1 
ATOM   2079  N  N   . ALA A 1 282 ? 13.585  50.099  28.692  1.00 52.90  ? 282 ALA A N   1 
ATOM   2080  C  CA  . ALA A 1 282 ? 14.275  51.360  28.567  1.00 49.46  ? 282 ALA A CA  1 
ATOM   2081  C  C   . ALA A 1 282 ? 15.377  51.239  27.516  1.00 54.67  ? 282 ALA A C   1 
ATOM   2082  O  O   . ALA A 1 282 ? 15.422  52.040  26.583  1.00 56.72  ? 282 ALA A O   1 
ATOM   2083  C  CB  . ALA A 1 282 ? 14.822  51.718  29.912  1.00 47.07  ? 282 ALA A CB  1 
ATOM   2084  N  N   . SER A 1 283 ? 16.214  50.200  27.620  1.00 52.82  ? 283 SER A N   1 
ATOM   2085  C  CA  . SER A 1 283 ? 17.417  50.151  26.797  1.00 50.45  ? 283 SER A CA  1 
ATOM   2086  C  C   . SER A 1 283 ? 17.292  49.238  25.581  1.00 51.00  ? 283 SER A C   1 
ATOM   2087  O  O   . SER A 1 283 ? 18.292  49.062  24.890  1.00 47.67  ? 283 SER A O   1 
ATOM   2088  C  CB  . SER A 1 283 ? 18.620  49.780  27.613  1.00 54.06  ? 283 SER A CB  1 
ATOM   2089  O  OG  . SER A 1 283 ? 18.291  48.686  28.440  1.00 60.31  ? 283 SER A OG  1 
ATOM   2090  N  N   . ALA A 1 284 ? 16.116  48.664  25.285  1.00 47.73  ? 284 ALA A N   1 
ATOM   2091  C  CA  . ALA A 1 284 ? 16.041  47.717  24.180  1.00 42.95  ? 284 ALA A CA  1 
ATOM   2092  C  C   . ALA A 1 284 ? 14.685  47.802  23.495  1.00 39.47  ? 284 ALA A C   1 
ATOM   2093  O  O   . ALA A 1 284 ? 13.658  47.575  24.116  1.00 43.88  ? 284 ALA A O   1 
ATOM   2094  C  CB  . ALA A 1 284 ? 16.295  46.294  24.666  1.00 48.06  ? 284 ALA A CB  1 
ATOM   2095  N  N   . PRO A 1 285 ? 14.614  48.069  22.181  1.00 37.99  ? 285 PRO A N   1 
ATOM   2096  C  CA  . PRO A 1 285 ? 13.312  48.179  21.503  1.00 35.41  ? 285 PRO A CA  1 
ATOM   2097  C  C   . PRO A 1 285 ? 12.473  46.904  21.564  1.00 36.45  ? 285 PRO A C   1 
ATOM   2098  O  O   . PRO A 1 285 ? 11.265  46.975  21.687  1.00 36.69  ? 285 PRO A O   1 
ATOM   2099  C  CB  . PRO A 1 285 ? 13.634  48.601  20.066  1.00 34.19  ? 285 PRO A CB  1 
ATOM   2100  C  CG  . PRO A 1 285 ? 15.093  48.235  19.909  1.00 38.00  ? 285 PRO A CG  1 
ATOM   2101  C  CD  . PRO A 1 285 ? 15.751  48.310  21.298  1.00 38.15  ? 285 PRO A CD  1 
ATOM   2102  N  N   . HIS A 1 286 ? 13.128  45.742  21.450  1.00 35.37  ? 286 HIS A N   1 
ATOM   2103  C  CA  . HIS A 1 286 ? 12.483  44.434  21.513  1.00 29.58  ? 286 HIS A CA  1 
ATOM   2104  C  C   . HIS A 1 286 ? 13.565  43.374  21.420  1.00 29.98  ? 286 HIS A C   1 
ATOM   2105  O  O   . HIS A 1 286 ? 14.715  43.687  21.122  1.00 32.61  ? 286 HIS A O   1 
ATOM   2106  C  CB  . HIS A 1 286 ? 11.474  44.241  20.392  1.00 29.98  ? 286 HIS A CB  1 
ATOM   2107  C  CG  . HIS A 1 286 ? 12.035  44.427  19.023  1.00 36.07  ? 286 HIS A CG  1 
ATOM   2108  N  ND1 . HIS A 1 286 ? 11.862  45.578  18.277  1.00 32.99  ? 286 HIS A ND1 1 
ATOM   2109  C  CD2 . HIS A 1 286 ? 12.746  43.589  18.253  1.00 36.56  ? 286 HIS A CD2 1 
ATOM   2110  C  CE1 . HIS A 1 286 ? 12.466  45.429  17.110  1.00 29.67  ? 286 HIS A CE1 1 
ATOM   2111  N  NE2 . HIS A 1 286 ? 12.994  44.233  17.068  1.00 30.10  ? 286 HIS A NE2 1 
ATOM   2112  N  N   . ASP A 1 287 ? 13.184  42.127  21.689  1.00 29.19  ? 287 ASP A N   1 
ATOM   2113  C  CA  . ASP A 1 287 ? 14.068  40.983  21.558  1.00 28.61  ? 287 ASP A CA  1 
ATOM   2114  C  C   . ASP A 1 287 ? 14.408  40.798  20.081  1.00 25.74  ? 287 ASP A C   1 
ATOM   2115  O  O   . ASP A 1 287 ? 13.535  40.628  19.239  1.00 24.99  ? 287 ASP A O   1 
ATOM   2116  C  CB  . ASP A 1 287 ? 13.391  39.764  22.156  1.00 30.54  ? 287 ASP A CB  1 
ATOM   2117  C  CG  . ASP A 1 287 ? 14.250  38.519  22.330  1.00 31.48  ? 287 ASP A CG  1 
ATOM   2118  O  OD1 . ASP A 1 287 ? 15.286  38.396  21.628  1.00 28.99  ? 287 ASP A OD1 1 
ATOM   2119  O  OD2 . ASP A 1 287 ? 13.857  37.666  23.175  1.00 29.35  ? 287 ASP A OD2 1 
ATOM   2120  N  N   . ARG A 1 288 ? 15.701  40.798  19.775  1.00 27.79  ? 288 ARG A N   1 
ATOM   2121  C  CA  . ARG A 1 288 ? 16.158  40.607  18.407  1.00 28.28  ? 288 ARG A CA  1 
ATOM   2122  C  C   . ARG A 1 288 ? 15.731  39.254  17.828  1.00 23.75  ? 288 ARG A C   1 
ATOM   2123  O  O   . ARG A 1 288 ? 15.669  39.110  16.617  1.00 24.60  ? 288 ARG A O   1 
ATOM   2124  C  CB  . ARG A 1 288 ? 17.684  40.737  18.352  1.00 32.32  ? 288 ARG A CB  1 
ATOM   2125  C  CG  . ARG A 1 288 ? 18.150  42.165  18.583  1.00 39.34  ? 288 ARG A CG  1 
ATOM   2126  C  CD  . ARG A 1 288 ? 17.943  42.964  17.283  1.00 44.37  ? 288 ARG A CD  1 
ATOM   2127  N  NE  . ARG A 1 288 ? 18.985  42.583  16.325  1.00 49.73  ? 288 ARG A NE  1 
ATOM   2128  C  CZ  . ARG A 1 288 ? 18.868  42.245  15.032  1.00 48.57  ? 288 ARG A CZ  1 
ATOM   2129  N  NH1 . ARG A 1 288 ? 17.696  42.236  14.443  1.00 49.33  ? 288 ARG A NH1 1 
ATOM   2130  N  NH2 . ARG A 1 288 ? 19.923  41.870  14.335  1.00 38.35  ? 288 ARG A NH2 1 
ATOM   2131  N  N   . ILE A 1 289 ? 15.445  38.259  18.659  1.00 21.35  ? 289 ILE A N   1 
ATOM   2132  C  CA  . ILE A 1 289 ? 15.064  36.967  18.133  1.00 23.94  ? 289 ILE A CA  1 
ATOM   2133  C  C   . ILE A 1 289 ? 13.741  37.086  17.358  1.00 23.44  ? 289 ILE A C   1 
ATOM   2134  O  O   . ILE A 1 289 ? 13.475  36.258  16.481  1.00 21.86  ? 289 ILE A O   1 
ATOM   2135  C  CB  . ILE A 1 289 ? 14.985  35.916  19.259  1.00 26.06  ? 289 ILE A CB  1 
ATOM   2136  C  CG1 . ILE A 1 289 ? 15.248  34.519  18.732  1.00 26.90  ? 289 ILE A CG1 1 
ATOM   2137  C  CG2 . ILE A 1 289 ? 13.631  35.964  19.982  1.00 26.92  ? 289 ILE A CG2 1 
ATOM   2138  C  CD1 . ILE A 1 289 ? 15.263  33.417  19.791  1.00 28.40  ? 289 ILE A CD1 1 
ATOM   2139  N  N   . LEU A 1 290 ? 12.906  38.095  17.694  1.00 23.75  ? 290 LEU A N   1 
ATOM   2140  C  CA  . LEU A 1 290 ? 11.617  38.300  17.043  1.00 22.71  ? 290 LEU A CA  1 
ATOM   2141  C  C   . LEU A 1 290 ? 11.805  38.892  15.644  1.00 24.29  ? 290 LEU A C   1 
ATOM   2142  O  O   . LEU A 1 290 ? 10.889  38.854  14.828  1.00 24.20  ? 290 LEU A O   1 
ATOM   2143  C  CB  . LEU A 1 290 ? 10.713  39.203  17.879  1.00 20.49  ? 290 LEU A CB  1 
ATOM   2144  C  CG  . LEU A 1 290 ? 10.366  38.639  19.248  1.00 20.76  ? 290 LEU A CG  1 
ATOM   2145  C  CD1 . LEU A 1 290 ? 9.532   39.663  19.993  1.00 22.07  ? 290 LEU A CD1 1 
ATOM   2146  C  CD2 . LEU A 1 290 ? 9.627   37.318  19.108  1.00 21.92  ? 290 LEU A CD2 1 
ATOM   2147  N  N   . ASP A 1 291 ? 13.008  39.399  15.332  1.00 22.56  ? 291 ASP A N   1 
ATOM   2148  C  CA  . ASP A 1 291 ? 13.246  39.814  13.967  1.00 22.22  ? 291 ASP A CA  1 
ATOM   2149  C  C   . ASP A 1 291 ? 13.397  38.601  13.058  1.00 22.57  ? 291 ASP A C   1 
ATOM   2150  O  O   . ASP A 1 291 ? 13.504  38.770  11.869  1.00 23.41  ? 291 ASP A O   1 
ATOM   2151  C  CB  . ASP A 1 291 ? 14.396  40.782  13.852  1.00 23.53  ? 291 ASP A CB  1 
ATOM   2152  C  CG  . ASP A 1 291 ? 14.187  42.129  14.530  1.00 25.74  ? 291 ASP A CG  1 
ATOM   2153  O  OD1 . ASP A 1 291 ? 13.067  42.668  14.459  1.00 32.28  ? 291 ASP A OD1 1 
ATOM   2154  O  OD2 . ASP A 1 291 ? 15.133  42.636  15.127  1.00 25.30  ? 291 ASP A OD2 1 
ATOM   2155  N  N   . PHE A 1 292 ? 13.417  37.380  13.601  1.00 22.80  ? 292 PHE A N   1 
ATOM   2156  C  CA  . PHE A 1 292 ? 13.536  36.189  12.768  1.00 22.07  ? 292 PHE A CA  1 
ATOM   2157  C  C   . PHE A 1 292 ? 12.511  35.133  13.150  1.00 23.69  ? 292 PHE A C   1 
ATOM   2158  O  O   . PHE A 1 292 ? 12.564  34.012  12.664  1.00 22.59  ? 292 PHE A O   1 
ATOM   2159  C  CB  . PHE A 1 292 ? 14.926  35.584  12.940  1.00 21.58  ? 292 PHE A CB  1 
ATOM   2160  C  CG  . PHE A 1 292 ? 16.014  36.601  12.669  1.00 21.06  ? 292 PHE A CG  1 
ATOM   2161  C  CD1 . PHE A 1 292 ? 16.463  36.812  11.389  1.00 22.67  ? 292 PHE A CD1 1 
ATOM   2162  C  CD2 . PHE A 1 292 ? 16.542  37.385  13.681  1.00 21.29  ? 292 PHE A CD2 1 
ATOM   2163  C  CE1 . PHE A 1 292 ? 17.467  37.730  11.132  1.00 21.64  ? 292 PHE A CE1 1 
ATOM   2164  C  CE2 . PHE A 1 292 ? 17.532  38.318  13.411  1.00 22.43  ? 292 PHE A CE2 1 
ATOM   2165  C  CZ  . PHE A 1 292 ? 17.994  38.469  12.140  1.00 21.18  ? 292 PHE A CZ  1 
ATOM   2166  N  N   . SER A 1 293 ? 11.564  35.506  14.013  1.00 25.95  ? 293 SER A N   1 
ATOM   2167  C  CA  . SER A 1 293 ? 10.609  34.560  14.552  1.00 24.41  ? 293 SER A CA  1 
ATOM   2168  C  C   . SER A 1 293 ? 9.252   35.250  14.607  1.00 26.80  ? 293 SER A C   1 
ATOM   2169  O  O   . SER A 1 293 ? 9.181   36.319  15.196  1.00 32.91  ? 293 SER A O   1 
ATOM   2170  C  CB  . SER A 1 293 ? 11.024  34.077  15.915  1.00 22.60  ? 293 SER A CB  1 
ATOM   2171  O  OG  . SER A 1 293 ? 12.410  33.827  15.964  1.00 22.18  ? 293 SER A OG  1 
ATOM   2172  N  N   . THR A 1 294 ? 8.212   34.643  14.006  1.00 23.23  ? 294 THR A N   1 
ATOM   2173  C  CA  . THR A 1 294 ? 6.857   35.153  14.088  1.00 23.23  ? 294 THR A CA  1 
ATOM   2174  C  C   . THR A 1 294 ? 5.983   34.173  14.862  1.00 23.18  ? 294 THR A C   1 
ATOM   2175  O  O   . THR A 1 294 ? 5.903   33.012  14.472  1.00 21.95  ? 294 THR A O   1 
ATOM   2176  C  CB  . THR A 1 294 ? 6.287   35.276  12.694  1.00 22.46  ? 294 THR A CB  1 
ATOM   2177  O  OG1 . THR A 1 294 ? 7.136   36.218  12.097  1.00 25.39  ? 294 THR A OG1 1 
ATOM   2178  C  CG2 . THR A 1 294 ? 4.922   35.911  12.714  1.00 25.16  ? 294 THR A CG2 1 
ATOM   2179  N  N   . ALA A 1 295 ? 5.290   34.680  15.901  1.00 25.00  ? 295 ALA A N   1 
ATOM   2180  C  CA  . ALA A 1 295 ? 4.301   33.918  16.638  1.00 24.48  ? 295 ALA A CA  1 
ATOM   2181  C  C   . ALA A 1 295 ? 3.012   33.860  15.855  1.00 22.13  ? 295 ALA A C   1 
ATOM   2182  O  O   . ALA A 1 295 ? 2.489   34.882  15.494  1.00 21.73  ? 295 ALA A O   1 
ATOM   2183  C  CB  . ALA A 1 295 ? 4.050   34.576  17.969  1.00 30.20  ? 295 ALA A CB  1 
ATOM   2184  N  N   . VAL A 1 296 ? 2.491   32.652  15.630  1.00 23.31  ? 296 VAL A N   1 
ATOM   2185  C  CA  . VAL A 1 296 ? 1.219   32.483  14.942  1.00 22.48  ? 296 VAL A CA  1 
ATOM   2186  C  C   . VAL A 1 296 ? 0.168   31.848  15.856  1.00 24.60  ? 296 VAL A C   1 
ATOM   2187  O  O   . VAL A 1 296 ? -0.977  31.728  15.432  1.00 26.32  ? 296 VAL A O   1 
ATOM   2188  C  CB  . VAL A 1 296 ? 1.399   31.674  13.652  1.00 21.61  ? 296 VAL A CB  1 
ATOM   2189  C  CG1 . VAL A 1 296 ? 2.510   32.255  12.814  1.00 23.62  ? 296 VAL A CG1 1 
ATOM   2190  C  CG2 . VAL A 1 296 ? 1.700   30.215  13.883  1.00 22.78  ? 296 VAL A CG2 1 
ATOM   2191  N  N   . THR A 1 297 ? 0.536   31.425  17.077  1.00 23.28  ? 297 THR A N   1 
ATOM   2192  C  CA  . THR A 1 297 ? -0.436  31.070  18.083  1.00 22.40  ? 297 THR A CA  1 
ATOM   2193  C  C   . THR A 1 297 ? -0.012  31.655  19.423  1.00 23.20  ? 297 THR A C   1 
ATOM   2194  O  O   . THR A 1 297 ? 1.081   32.168  19.625  1.00 22.23  ? 297 THR A O   1 
ATOM   2195  C  CB  . THR A 1 297 ? -0.672  29.576  18.214  1.00 21.80  ? 297 THR A CB  1 
ATOM   2196  O  OG1 . THR A 1 297 ? 0.467   28.968  18.815  1.00 23.15  ? 297 THR A OG1 1 
ATOM   2197  C  CG2 . THR A 1 297 ? -1.007  28.927  16.901  1.00 20.38  ? 297 THR A CG2 1 
ATOM   2198  N  N   . GLY A 1 298 ? -0.989  31.643  20.319  1.00 27.21  ? 298 GLY A N   1 
ATOM   2199  C  CA  . GLY A 1 298 ? -0.791  32.105  21.682  1.00 30.58  ? 298 GLY A CA  1 
ATOM   2200  C  C   . GLY A 1 298 ? -1.947  31.649  22.568  1.00 27.60  ? 298 GLY A C   1 
ATOM   2201  O  O   . GLY A 1 298 ? -3.074  32.009  22.311  1.00 25.83  ? 298 GLY A O   1 
ATOM   2202  N  N   . SER A 1 299 ? -1.654  30.870  23.608  1.00 27.09  ? 299 SER A N   1 
ATOM   2203  C  CA  . SER A 1 299 ? -2.666  30.364  24.510  1.00 23.33  ? 299 SER A CA  1 
ATOM   2204  C  C   . SER A 1 299 ? -2.057  30.160  25.895  1.00 24.35  ? 299 SER A C   1 
ATOM   2205  O  O   . SER A 1 299 ? -0.851  29.918  26.016  1.00 20.82  ? 299 SER A O   1 
ATOM   2206  C  CB  . SER A 1 299 ? -3.239  29.062  24.008  1.00 20.11  ? 299 SER A CB  1 
ATOM   2207  O  OG  . SER A 1 299 ? -3.753  29.191  22.700  1.00 18.99  ? 299 SER A OG  1 
ATOM   2208  N  N   . LEU A 1 300 ? -2.928  30.241  26.910  1.00 22.05  ? 300 LEU A N   1 
ATOM   2209  C  CA  . LEU A 1 300 ? -2.572  30.018  28.295  1.00 21.73  ? 300 LEU A CA  1 
ATOM   2210  C  C   . LEU A 1 300 ? -3.483  28.949  28.875  1.00 20.45  ? 300 LEU A C   1 
ATOM   2211  O  O   . LEU A 1 300 ? -4.689  28.965  28.661  1.00 24.51  ? 300 LEU A O   1 
ATOM   2212  C  CB  . LEU A 1 300 ? -2.692  31.341  29.035  1.00 22.56  ? 300 LEU A CB  1 
ATOM   2213  C  CG  . LEU A 1 300 ? -2.138  31.382  30.465  1.00 22.28  ? 300 LEU A CG  1 
ATOM   2214  C  CD1 . LEU A 1 300 ? -1.951  32.801  30.898  1.00 23.60  ? 300 LEU A CD1 1 
ATOM   2215  C  CD2 . LEU A 1 300 ? -3.078  30.724  31.433  1.00 24.04  ? 300 LEU A CD2 1 
ATOM   2216  N  N   . PHE A 1 301 ? -2.896  28.034  29.635  1.00 19.14  ? 301 PHE A N   1 
ATOM   2217  C  CA  . PHE A 1 301 ? -3.647  26.956  30.239  1.00 20.14  ? 301 PHE A CA  1 
ATOM   2218  C  C   . PHE A 1 301 ? -3.193  26.763  31.670  1.00 21.30  ? 301 PHE A C   1 
ATOM   2219  O  O   . PHE A 1 301 ? -2.073  27.102  32.045  1.00 22.93  ? 301 PHE A O   1 
ATOM   2220  C  CB  . PHE A 1 301 ? -3.440  25.640  29.504  1.00 21.29  ? 301 PHE A CB  1 
ATOM   2221  C  CG  . PHE A 1 301 ? -3.740  25.711  28.019  1.00 21.79  ? 301 PHE A CG  1 
ATOM   2222  C  CD1 . PHE A 1 301 ? -2.812  26.180  27.106  1.00 21.92  ? 301 PHE A CD1 1 
ATOM   2223  C  CD2 . PHE A 1 301 ? -4.962  25.315  27.527  1.00 28.71  ? 301 PHE A CD2 1 
ATOM   2224  C  CE1 . PHE A 1 301 ? -3.083  26.224  25.764  1.00 23.60  ? 301 PHE A CE1 1 
ATOM   2225  C  CE2 . PHE A 1 301 ? -5.245  25.373  26.160  1.00 26.83  ? 301 PHE A CE2 1 
ATOM   2226  C  CZ  . PHE A 1 301 ? -4.292  25.793  25.288  1.00 25.63  ? 301 PHE A CZ  1 
ATOM   2227  N  N   . PHE A 1 302 ? -4.127  26.247  32.466  1.00 24.60  ? 302 PHE A N   1 
ATOM   2228  C  CA  . PHE A 1 302 ? -3.818  25.775  33.807  1.00 24.80  ? 302 PHE A CA  1 
ATOM   2229  C  C   . PHE A 1 302 ? -3.753  24.250  33.775  1.00 22.89  ? 302 PHE A C   1 
ATOM   2230  O  O   . PHE A 1 302 ? -4.661  23.602  33.249  1.00 23.77  ? 302 PHE A O   1 
ATOM   2231  C  CB  . PHE A 1 302 ? -4.874  26.288  34.788  1.00 23.61  ? 302 PHE A CB  1 
ATOM   2232  C  CG  . PHE A 1 302 ? -4.582  25.845  36.211  1.00 21.74  ? 302 PHE A CG  1 
ATOM   2233  C  CD1 . PHE A 1 302 ? -3.579  26.485  36.932  1.00 21.43  ? 302 PHE A CD1 1 
ATOM   2234  C  CD2 . PHE A 1 302 ? -5.270  24.776  36.786  1.00 19.85  ? 302 PHE A CD2 1 
ATOM   2235  C  CE1 . PHE A 1 302 ? -3.287  26.077  38.229  1.00 22.60  ? 302 PHE A CE1 1 
ATOM   2236  C  CE2 . PHE A 1 302 ? -4.957  24.353  38.060  1.00 20.94  ? 302 PHE A CE2 1 
ATOM   2237  C  CZ  . PHE A 1 302 ? -3.984  25.016  38.794  1.00 21.22  ? 302 PHE A CZ  1 
ATOM   2238  N  N   . THR A 1 303 ? -2.662  23.705  34.299  1.00 22.04  ? 303 THR A N   1 
ATOM   2239  C  CA  . THR A 1 303 ? -2.466  22.271  34.337  1.00 22.59  ? 303 THR A CA  1 
ATOM   2240  C  C   . THR A 1 303 ? -2.647  21.849  35.780  1.00 23.64  ? 303 THR A C   1 
ATOM   2241  O  O   . THR A 1 303 ? -1.748  22.045  36.594  1.00 26.30  ? 303 THR A O   1 
ATOM   2242  C  CB  . THR A 1 303 ? -1.095  21.862  33.771  1.00 24.59  ? 303 THR A CB  1 
ATOM   2243  O  OG1 . THR A 1 303 ? -0.047  22.440  34.538  1.00 22.54  ? 303 THR A OG1 1 
ATOM   2244  C  CG2 . THR A 1 303 ? -0.872  22.363  32.350  1.00 23.48  ? 303 THR A CG2 1 
ATOM   2245  N  N   . PRO A 1 304 ? -3.809  21.267  36.128  1.00 24.56  ? 304 PRO A N   1 
ATOM   2246  C  CA  . PRO A 1 304 ? -4.130  20.916  37.505  1.00 26.69  ? 304 PRO A CA  1 
ATOM   2247  C  C   . PRO A 1 304 ? -3.250  19.819  38.058  1.00 24.70  ? 304 PRO A C   1 
ATOM   2248  O  O   . PRO A 1 304 ? -2.630  19.081  37.310  1.00 25.09  ? 304 PRO A O   1 
ATOM   2249  C  CB  . PRO A 1 304 ? -5.591  20.442  37.473  1.00 27.25  ? 304 PRO A CB  1 
ATOM   2250  C  CG  . PRO A 1 304 ? -6.094  20.822  36.121  1.00 27.78  ? 304 PRO A CG  1 
ATOM   2251  C  CD  . PRO A 1 304 ? -4.904  20.923  35.219  1.00 27.45  ? 304 PRO A CD  1 
ATOM   2252  N  N   . ALA A 1 305 ? -3.247  19.720  39.384  1.00 26.30  ? 305 ALA A N   1 
ATOM   2253  C  CA  . ALA A 1 305 ? -2.736  18.540  40.053  1.00 25.71  ? 305 ALA A CA  1 
ATOM   2254  C  C   . ALA A 1 305 ? -3.492  17.314  39.534  1.00 30.63  ? 305 ALA A C   1 
ATOM   2255  O  O   . ALA A 1 305 ? -4.657  17.387  39.113  1.00 31.57  ? 305 ALA A O   1 
ATOM   2256  C  CB  . ALA A 1 305 ? -2.835  18.651  41.552  1.00 24.88  ? 305 ALA A CB  1 
ATOM   2257  N  N   . ALA A 1 306 ? -2.768  16.188  39.508  1.00 31.31  ? 306 ALA A N   1 
ATOM   2258  C  CA  . ALA A 1 306 ? -3.284  14.923  39.035  1.00 30.05  ? 306 ALA A CA  1 
ATOM   2259  C  C   . ALA A 1 306 ? -4.550  14.527  39.787  1.00 35.23  ? 306 ALA A C   1 
ATOM   2260  O  O   . ALA A 1 306 ? -5.489  14.079  39.132  1.00 35.15  ? 306 ALA A O   1 
ATOM   2261  C  CB  . ALA A 1 306 ? -2.204  13.867  39.161  1.00 31.84  ? 306 ALA A CB  1 
ATOM   2262  N  N   . ASP A 1 307 ? -4.581  14.694  41.127  1.00 44.38  ? 307 ASP A N   1 
ATOM   2263  C  CA  . ASP A 1 307 ? -5.729  14.243  41.914  1.00 47.31  ? 307 ASP A CA  1 
ATOM   2264  C  C   . ASP A 1 307 ? -6.987  14.997  41.493  1.00 48.54  ? 307 ASP A C   1 
ATOM   2265  O  O   . ASP A 1 307 ? -8.076  14.403  41.501  1.00 51.11  ? 307 ASP A O   1 
ATOM   2266  C  CB  . ASP A 1 307 ? -5.587  14.405  43.418  1.00 55.29  ? 307 ASP A CB  1 
ATOM   2267  C  CG  . ASP A 1 307 ? -4.176  14.604  43.941  1.00 60.19  ? 307 ASP A CG  1 
ATOM   2268  O  OD1 . ASP A 1 307 ? -3.807  15.780  44.118  1.00 64.40  ? 307 ASP A OD1 1 
ATOM   2269  O  OD2 . ASP A 1 307 ? -3.482  13.587  44.186  1.00 73.88  ? 307 ASP A OD2 1 
ATOM   2270  N  N   . PHE A 1 308 ? -6.844  16.284  41.115  1.00 42.23  ? 308 PHE A N   1 
ATOM   2271  C  CA  . PHE A 1 308 ? -7.977  17.082  40.670  1.00 35.26  ? 308 PHE A CA  1 
ATOM   2272  C  C   . PHE A 1 308 ? -8.692  16.387  39.509  1.00 40.14  ? 308 PHE A C   1 
ATOM   2273  O  O   . PHE A 1 308 ? -9.910  16.332  39.491  1.00 45.49  ? 308 PHE A O   1 
ATOM   2274  C  CB  . PHE A 1 308 ? -7.554  18.509  40.325  1.00 31.87  ? 308 PHE A CB  1 
ATOM   2275  C  CG  . PHE A 1 308 ? -8.705  19.379  39.848  1.00 35.92  ? 308 PHE A CG  1 
ATOM   2276  C  CD1 . PHE A 1 308 ? -9.115  19.352  38.512  1.00 39.78  ? 308 PHE A CD1 1 
ATOM   2277  C  CD2 . PHE A 1 308 ? -9.387  20.216  40.732  1.00 41.24  ? 308 PHE A CD2 1 
ATOM   2278  C  CE1 . PHE A 1 308 ? -10.156 20.154  38.073  1.00 41.86  ? 308 PHE A CE1 1 
ATOM   2279  C  CE2 . PHE A 1 308 ? -10.427 21.018  40.289  1.00 40.52  ? 308 PHE A CE2 1 
ATOM   2280  C  CZ  . PHE A 1 308 ? -10.806 20.983  38.962  1.00 44.35  ? 308 PHE A CZ  1 
ATOM   2281  N  N   . LEU A 1 309 ? -7.940  15.839  38.554  1.00 43.22  ? 309 LEU A N   1 
ATOM   2282  C  CA  . LEU A 1 309 ? -8.513  15.199  37.375  1.00 48.18  ? 309 LEU A CA  1 
ATOM   2283  C  C   . LEU A 1 309 ? -9.108  13.828  37.721  1.00 45.78  ? 309 LEU A C   1 
ATOM   2284  O  O   . LEU A 1 309 ? -10.129 13.466  37.154  1.00 41.28  ? 309 LEU A O   1 
ATOM   2285  C  CB  . LEU A 1 309 ? -7.475  15.099  36.250  1.00 47.97  ? 309 LEU A CB  1 
ATOM   2286  C  CG  . LEU A 1 309 ? -6.927  16.436  35.717  1.00 43.82  ? 309 LEU A CG  1 
ATOM   2287  C  CD1 . LEU A 1 309 ? -5.784  16.142  34.828  1.00 50.30  ? 309 LEU A CD1 1 
ATOM   2288  C  CD2 . LEU A 1 309 ? -7.909  17.254  34.934  1.00 44.06  ? 309 LEU A CD2 1 
ATOM   2289  N  N   . GLU A 1 310 ? -8.471  13.071  38.630  1.00 48.73  ? 310 GLU A N   1 
ATOM   2290  C  CA  . GLU A 1 310 ? -8.915  11.726  39.005  1.00 53.27  ? 310 GLU A CA  1 
ATOM   2291  C  C   . GLU A 1 310 ? -10.366 11.836  39.480  1.00 50.21  ? 310 GLU A C   1 
ATOM   2292  O  O   . GLU A 1 310 ? -11.180 11.036  39.046  1.00 53.19  ? 310 GLU A O   1 
ATOM   2293  C  CB  . GLU A 1 310 ? -7.975  11.041  40.018  1.00 66.38  ? 310 GLU A CB  1 
ATOM   2294  C  CG  . GLU A 1 310 ? -7.801  9.521   39.886  1.00 69.89  ? 310 GLU A CG  1 
ATOM   2295  C  CD  . GLU A 1 310 ? -6.655  8.913   40.695  1.00 80.27  ? 310 GLU A CD  1 
ATOM   2296  O  OE1 . GLU A 1 310 ? -5.597  8.677   40.076  1.00 77.28  ? 310 GLU A OE1 1 
ATOM   2297  O  OE2 . GLU A 1 310 ? -6.779  8.648   41.917  1.00 95.32  ? 310 GLU A OE2 1 
ATOM   2298  N  N   . ASP A 1 311 ? -10.713 12.881  40.262  1.00 50.95  ? 311 ASP A N   1 
ATOM   2299  C  CA  . ASP A 1 311 ? -11.972 12.936  41.009  1.00 59.02  ? 311 ASP A CA  1 
ATOM   2300  C  C   . ASP A 1 311 ? -13.125 13.597  40.244  1.00 56.18  ? 311 ASP A C   1 
ATOM   2301  O  O   . ASP A 1 311 ? -13.632 14.574  40.743  1.00 61.70  ? 311 ASP A O   1 
ATOM   2302  C  CB  . ASP A 1 311 ? -11.783 13.651  42.346  1.00 60.50  ? 311 ASP A CB  1 
ATOM   2303  C  CG  . ASP A 1 311 ? -10.659 13.115  43.229  1.00 70.60  ? 311 ASP A CG  1 
ATOM   2304  O  OD1 . ASP A 1 311 ? -10.185 11.977  43.009  1.00 79.22  ? 311 ASP A OD1 1 
ATOM   2305  O  OD2 . ASP A 1 311 ? -10.218 13.842  44.141  1.00 65.70  ? 311 ASP A OD2 1 
ATOM   2306  N  N   . LEU A 1 312 ? -13.604 13.011  39.123  1.00 64.38  ? 312 LEU A N   1 
ATOM   2307  C  CA  . LEU A 1 312 ? -14.506 13.634  38.152  1.00 66.87  ? 312 LEU A CA  1 
ATOM   2308  C  C   . LEU A 1 312 ? -15.398 12.554  37.499  1.00 54.83  ? 312 LEU A C   1 
ATOM   2309  O  O   . LEU A 1 312 ? -16.012 11.825  38.262  1.00 67.98  ? 312 LEU A O   1 
ATOM   2310  C  CB  . LEU A 1 312 ? -13.780 14.375  37.020  1.00 65.28  ? 312 LEU A CB  1 
ATOM   2311  C  CG  . LEU A 1 312 ? -13.005 15.669  37.328  1.00 57.03  ? 312 LEU A CG  1 
ATOM   2312  C  CD1 . LEU A 1 312 ? -12.763 16.399  36.020  1.00 56.76  ? 312 LEU A CD1 1 
ATOM   2313  C  CD2 . LEU A 1 312 ? -13.633 16.648  38.307  1.00 53.57  ? 312 LEU A CD2 1 
ATOM   2314  N  N   . GLU B 1 7   ? 24.596  -20.768 -5.740  1.00 89.93  ? 7   GLU B N   1 
ATOM   2315  C  CA  . GLU B 1 7   ? 23.661  -21.531 -4.863  1.00 90.71  ? 7   GLU B CA  1 
ATOM   2316  C  C   . GLU B 1 7   ? 23.893  -21.034 -3.414  1.00 94.39  ? 7   GLU B C   1 
ATOM   2317  O  O   . GLU B 1 7   ? 24.028  -19.832 -3.214  1.00 65.62  ? 7   GLU B O   1 
ATOM   2318  C  CB  . GLU B 1 7   ? 23.653  -23.028 -5.247  1.00 61.79  ? 7   GLU B CB  1 
ATOM   2319  N  N   . PRO B 1 8   ? 24.142  -21.885 -2.380  1.00 93.20  ? 8   PRO B N   1 
ATOM   2320  C  CA  . PRO B 1 8   ? 23.224  -21.996 -1.243  1.00 83.78  ? 8   PRO B CA  1 
ATOM   2321  C  C   . PRO B 1 8   ? 23.317  -21.066 -0.028  1.00 80.03  ? 8   PRO B C   1 
ATOM   2322  O  O   . PRO B 1 8   ? 24.409  -20.750 0.430   1.00 75.72  ? 8   PRO B O   1 
ATOM   2323  C  CB  . PRO B 1 8   ? 23.508  -23.485 -0.893  1.00 79.88  ? 8   PRO B CB  1 
ATOM   2324  C  CG  . PRO B 1 8   ? 25.000  -23.654 -1.139  1.00 77.70  ? 8   PRO B CG  1 
ATOM   2325  C  CD  . PRO B 1 8   ? 25.401  -22.617 -2.165  1.00 79.34  ? 8   PRO B CD  1 
ATOM   2326  N  N   . GLU B 1 9   ? 22.141  -20.659 0.510   1.00 70.99  ? 9   GLU B N   1 
ATOM   2327  C  CA  . GLU B 1 9   ? 22.004  -19.981 1.806   1.00 59.25  ? 9   GLU B CA  1 
ATOM   2328  C  C   . GLU B 1 9   ? 22.228  -21.061 2.889   1.00 57.24  ? 9   GLU B C   1 
ATOM   2329  O  O   . GLU B 1 9   ? 21.504  -22.069 2.978   1.00 45.12  ? 9   GLU B O   1 
ATOM   2330  C  CB  . GLU B 1 9   ? 20.728  -19.122 1.929   1.00 42.95  ? 9   GLU B CB  1 
ATOM   2331  N  N   . PRO B 1 10  ? 23.282  -20.942 3.745   1.00 50.75  ? 10  PRO B N   1 
ATOM   2332  C  CA  . PRO B 1 10  ? 23.398  -21.813 4.927   1.00 51.23  ? 10  PRO B CA  1 
ATOM   2333  C  C   . PRO B 1 10  ? 22.413  -21.418 6.024   1.00 46.01  ? 10  PRO B C   1 
ATOM   2334  O  O   . PRO B 1 10  ? 21.887  -20.299 5.998   1.00 34.72  ? 10  PRO B O   1 
ATOM   2335  C  CB  . PRO B 1 10  ? 24.838  -21.618 5.389   1.00 43.77  ? 10  PRO B CB  1 
ATOM   2336  C  CG  . PRO B 1 10  ? 25.127  -20.201 4.965   1.00 41.42  ? 10  PRO B CG  1 
ATOM   2337  C  CD  . PRO B 1 10  ? 24.388  -19.978 3.648   1.00 41.79  ? 10  PRO B CD  1 
ATOM   2338  N  N   . GLN B 1 11  ? 22.216  -22.309 7.012   1.00 44.69  ? 11  GLN B N   1 
ATOM   2339  C  CA  . GLN B 1 11  ? 21.444  -21.916 8.187   1.00 35.34  ? 11  GLN B CA  1 
ATOM   2340  C  C   . GLN B 1 11  ? 22.275  -20.910 8.967   1.00 36.79  ? 11  GLN B C   1 
ATOM   2341  O  O   . GLN B 1 11  ? 23.416  -20.655 8.552   1.00 36.34  ? 11  GLN B O   1 
ATOM   2342  C  CB  . GLN B 1 11  ? 21.021  -23.102 9.041   1.00 33.38  ? 11  GLN B CB  1 
ATOM   2343  C  CG  . GLN B 1 11  ? 19.984  -23.985 8.373   1.00 33.17  ? 11  GLN B CG  1 
ATOM   2344  C  CD  . GLN B 1 11  ? 19.548  -25.090 9.289   1.00 37.05  ? 11  GLN B CD  1 
ATOM   2345  O  OE1 . GLN B 1 11  ? 18.988  -24.842 10.352  1.00 33.77  ? 11  GLN B OE1 1 
ATOM   2346  N  NE2 . GLN B 1 11  ? 19.849  -26.317 8.902   1.00 43.51  ? 11  GLN B NE2 1 
ATOM   2347  N  N   . MET B 1 12  ? 21.738  -20.389 10.080  1.00 36.33  ? 12  MET B N   1 
ATOM   2348  C  CA  . MET B 1 12  ? 22.454  -19.356 10.825  1.00 45.02  ? 12  MET B CA  1 
ATOM   2349  C  C   . MET B 1 12  ? 23.523  -19.961 11.732  1.00 36.78  ? 12  MET B C   1 
ATOM   2350  O  O   . MET B 1 12  ? 23.553  -19.710 12.917  1.00 30.61  ? 12  MET B O   1 
ATOM   2351  C  CB  . MET B 1 12  ? 21.494  -18.501 11.660  1.00 59.53  ? 12  MET B CB  1 
ATOM   2352  C  CG  . MET B 1 12  ? 22.085  -17.191 12.198  1.00 66.56  ? 12  MET B CG  1 
ATOM   2353  S  SD  . MET B 1 12  ? 22.526  -16.047 10.889  1.00 69.39  ? 12  MET B SD  1 
ATOM   2354  C  CE  . MET B 1 12  ? 21.609  -16.489 9.392   1.00 63.85  ? 12  MET B CE  1 
ATOM   2355  N  N   . VAL B 1 13  ? 24.443  -20.716 11.160  1.00 40.40  ? 13  VAL B N   1 
ATOM   2356  C  CA  . VAL B 1 13  ? 25.433  -21.395 11.963  1.00 41.74  ? 13  VAL B CA  1 
ATOM   2357  C  C   . VAL B 1 13  ? 26.379  -20.364 12.555  1.00 38.89  ? 13  VAL B C   1 
ATOM   2358  O  O   . VAL B 1 13  ? 26.616  -20.425 13.744  1.00 43.91  ? 13  VAL B O   1 
ATOM   2359  C  CB  . VAL B 1 13  ? 26.164  -22.487 11.168  1.00 50.24  ? 13  VAL B CB  1 
ATOM   2360  C  CG1 . VAL B 1 13  ? 27.315  -23.079 11.970  1.00 55.44  ? 13  VAL B CG1 1 
ATOM   2361  C  CG2 . VAL B 1 13  ? 25.195  -23.595 10.733  1.00 52.22  ? 13  VAL B CG2 1 
ATOM   2362  N  N   . LEU B 1 14  ? 26.873  -19.422 11.748  1.00 39.60  ? 14  LEU B N   1 
ATOM   2363  C  CA  . LEU B 1 14  ? 27.673  -18.298 12.232  1.00 47.43  ? 14  LEU B CA  1 
ATOM   2364  C  C   . LEU B 1 14  ? 26.725  -17.229 12.766  1.00 49.02  ? 14  LEU B C   1 
ATOM   2365  O  O   . LEU B 1 14  ? 26.163  -16.444 12.030  1.00 60.89  ? 14  LEU B O   1 
ATOM   2366  C  CB  . LEU B 1 14  ? 28.533  -17.703 11.118  1.00 54.20  ? 14  LEU B CB  1 
ATOM   2367  C  CG  . LEU B 1 14  ? 29.119  -18.700 10.113  1.00 54.51  ? 14  LEU B CG  1 
ATOM   2368  C  CD1 . LEU B 1 14  ? 29.465  -18.074 8.778   1.00 55.23  ? 14  LEU B CD1 1 
ATOM   2369  C  CD2 . LEU B 1 14  ? 30.344  -19.292 10.742  1.00 65.97  ? 14  LEU B CD2 1 
ATOM   2370  N  N   . SER B 1 15  ? 26.461  -17.255 14.050  1.00 52.20  ? 15  SER B N   1 
ATOM   2371  C  CA  . SER B 1 15  ? 25.526  -16.316 14.621  1.00 54.47  ? 15  SER B CA  1 
ATOM   2372  C  C   . SER B 1 15  ? 26.392  -15.303 15.360  1.00 55.97  ? 15  SER B C   1 
ATOM   2373  O  O   . SER B 1 15  ? 27.480  -15.646 15.811  1.00 54.42  ? 15  SER B O   1 
ATOM   2374  C  CB  . SER B 1 15  ? 24.511  -17.052 15.511  1.00 59.80  ? 15  SER B CB  1 
ATOM   2375  O  OG  . SER B 1 15  ? 23.943  -16.187 16.489  1.00 63.45  ? 15  SER B OG  1 
ATOM   2376  N  N   . PRO B 1 16  ? 26.001  -14.016 15.441  1.00 62.21  ? 16  PRO B N   1 
ATOM   2377  C  CA  . PRO B 1 16  ? 26.522  -13.123 16.480  1.00 63.55  ? 16  PRO B CA  1 
ATOM   2378  C  C   . PRO B 1 16  ? 26.575  -13.799 17.844  1.00 56.26  ? 16  PRO B C   1 
ATOM   2379  O  O   . PRO B 1 16  ? 25.933  -14.821 18.044  1.00 56.65  ? 16  PRO B O   1 
ATOM   2380  C  CB  . PRO B 1 16  ? 25.535  -11.930 16.505  1.00 62.02  ? 16  PRO B CB  1 
ATOM   2381  C  CG  . PRO B 1 16  ? 24.515  -12.267 15.444  1.00 62.66  ? 16  PRO B CG  1 
ATOM   2382  C  CD  . PRO B 1 16  ? 25.081  -13.339 14.523  1.00 60.44  ? 16  PRO B CD  1 
ATOM   2383  N  N   . LEU B 1 17  ? 27.352  -13.210 18.761  1.00 54.20  ? 17  LEU B N   1 
ATOM   2384  C  CA  . LEU B 1 17  ? 27.318  -13.549 20.172  1.00 52.31  ? 17  LEU B CA  1 
ATOM   2385  C  C   . LEU B 1 17  ? 25.870  -13.326 20.657  1.00 50.34  ? 17  LEU B C   1 
ATOM   2386  O  O   . LEU B 1 17  ? 25.225  -12.318 20.346  1.00 48.89  ? 17  LEU B O   1 
ATOM   2387  C  CB  . LEU B 1 17  ? 28.372  -12.732 20.950  1.00 51.22  ? 17  LEU B CB  1 
ATOM   2388  C  CG  . LEU B 1 17  ? 29.840  -13.198 20.914  1.00 42.00  ? 17  LEU B CG  1 
ATOM   2389  N  N   . THR B 1 18  ? 25.325  -14.351 21.320  1.00 43.71  ? 18  THR B N   1 
ATOM   2390  C  CA  . THR B 1 18  ? 23.992  -14.361 21.890  1.00 41.36  ? 18  THR B CA  1 
ATOM   2391  C  C   . THR B 1 18  ? 24.165  -14.840 23.326  1.00 37.11  ? 18  THR B C   1 
ATOM   2392  O  O   . THR B 1 18  ? 25.093  -15.590 23.612  1.00 37.34  ? 18  THR B O   1 
ATOM   2393  C  CB  . THR B 1 18  ? 23.052  -15.300 21.121  1.00 41.88  ? 18  THR B CB  1 
ATOM   2394  O  OG1 . THR B 1 18  ? 23.701  -16.580 21.088  1.00 46.84  ? 18  THR B OG1 1 
ATOM   2395  C  CG2 . THR B 1 18  ? 22.716  -14.812 19.719  1.00 39.18  ? 18  THR B CG2 1 
ATOM   2396  N  N   . SER B 1 19  ? 23.270  -14.433 24.223  1.00 34.38  ? 19  SER B N   1 
ATOM   2397  C  CA  . SER B 1 19  ? 23.474  -14.732 25.624  1.00 29.71  ? 19  SER B CA  1 
ATOM   2398  C  C   . SER B 1 19  ? 22.487  -15.778 26.114  1.00 28.70  ? 19  SER B C   1 
ATOM   2399  O  O   . SER B 1 19  ? 22.617  -16.179 27.252  1.00 28.58  ? 19  SER B O   1 
ATOM   2400  C  CB  . SER B 1 19  ? 23.425  -13.507 26.434  1.00 31.53  ? 19  SER B CB  1 
ATOM   2401  O  OG  . SER B 1 19  ? 22.615  -12.596 25.736  1.00 37.68  ? 19  SER B OG  1 
ATOM   2402  N  N   . ALA B 1 20  ? 21.564  -16.256 25.262  1.00 26.23  ? 20  ALA B N   1 
ATOM   2403  C  CA  . ALA B 1 20  ? 20.607  -17.258 25.711  1.00 25.62  ? 20  ALA B CA  1 
ATOM   2404  C  C   . ALA B 1 20  ? 20.395  -18.303 24.636  1.00 24.19  ? 20  ALA B C   1 
ATOM   2405  O  O   . ALA B 1 20  ? 20.474  -17.990 23.455  1.00 27.62  ? 20  ALA B O   1 
ATOM   2406  C  CB  . ALA B 1 20  ? 19.297  -16.600 26.058  1.00 26.77  ? 20  ALA B CB  1 
ATOM   2407  N  N   . ALA B 1 21  ? 20.113  -19.541 25.047  1.00 22.56  ? 21  ALA B N   1 
ATOM   2408  C  CA  . ALA B 1 21  ? 19.935  -20.615 24.094  1.00 21.21  ? 21  ALA B CA  1 
ATOM   2409  C  C   . ALA B 1 21  ? 18.997  -21.659 24.675  1.00 24.09  ? 21  ALA B C   1 
ATOM   2410  O  O   . ALA B 1 21  ? 18.948  -21.843 25.885  1.00 24.44  ? 21  ALA B O   1 
ATOM   2411  C  CB  . ALA B 1 21  ? 21.247  -21.232 23.721  1.00 19.64  ? 21  ALA B CB  1 
ATOM   2412  N  N   . ILE B 1 22  ? 18.240  -22.290 23.773  1.00 24.09  ? 22  ILE B N   1 
ATOM   2413  C  CA  . ILE B 1 22  ? 17.563  -23.522 24.084  1.00 24.19  ? 22  ILE B CA  1 
ATOM   2414  C  C   . ILE B 1 22  ? 18.079  -24.582 23.129  1.00 25.04  ? 22  ILE B C   1 
ATOM   2415  O  O   . ILE B 1 22  ? 18.128  -24.358 21.929  1.00 22.91  ? 22  ILE B O   1 
ATOM   2416  C  CB  . ILE B 1 22  ? 16.041  -23.393 24.031  1.00 26.27  ? 22  ILE B CB  1 
ATOM   2417  C  CG1 . ILE B 1 22  ? 15.505  -22.628 25.251  1.00 25.62  ? 22  ILE B CG1 1 
ATOM   2418  C  CG2 . ILE B 1 22  ? 15.401  -24.784 23.936  1.00 28.14  ? 22  ILE B CG2 1 
ATOM   2419  C  CD1 . ILE B 1 22  ? 14.022  -22.298 25.163  1.00 24.55  ? 22  ILE B CD1 1 
ATOM   2420  N  N   . PHE B 1 23  ? 18.502  -25.705 23.719  1.00 25.97  ? 23  PHE B N   1 
ATOM   2421  C  CA  . PHE B 1 23  ? 18.859  -26.901 22.993  1.00 27.52  ? 23  PHE B CA  1 
ATOM   2422  C  C   . PHE B 1 23  ? 17.765  -27.937 23.189  1.00 29.56  ? 23  PHE B C   1 
ATOM   2423  O  O   . PHE B 1 23  ? 17.534  -28.371 24.297  1.00 29.04  ? 23  PHE B O   1 
ATOM   2424  C  CB  . PHE B 1 23  ? 20.169  -27.515 23.495  1.00 28.11  ? 23  PHE B CB  1 
ATOM   2425  C  CG  . PHE B 1 23  ? 21.330  -26.555 23.410  1.00 28.70  ? 23  PHE B CG  1 
ATOM   2426  C  CD1 . PHE B 1 23  ? 22.101  -26.463 22.251  1.00 26.89  ? 23  PHE B CD1 1 
ATOM   2427  C  CD2 . PHE B 1 23  ? 21.635  -25.749 24.505  1.00 31.13  ? 23  PHE B CD2 1 
ATOM   2428  C  CE1 . PHE B 1 23  ? 23.163  -25.585 22.185  1.00 27.67  ? 23  PHE B CE1 1 
ATOM   2429  C  CE2 . PHE B 1 23  ? 22.724  -24.899 24.456  1.00 30.19  ? 23  PHE B CE2 1 
ATOM   2430  C  CZ  . PHE B 1 23  ? 23.481  -24.808 23.292  1.00 31.18  ? 23  PHE B CZ  1 
ATOM   2431  N  N   . LEU B 1 24  ? 17.190  -28.386 22.083  1.00 30.21  ? 24  LEU B N   1 
ATOM   2432  C  CA  . LEU B 1 24  ? 16.096  -29.333 22.097  1.00 29.47  ? 24  LEU B CA  1 
ATOM   2433  C  C   . LEU B 1 24  ? 16.482  -30.527 21.236  1.00 31.70  ? 24  LEU B C   1 
ATOM   2434  O  O   . LEU B 1 24  ? 16.842  -30.357 20.074  1.00 29.69  ? 24  LEU B O   1 
ATOM   2435  C  CB  . LEU B 1 24  ? 14.953  -28.535 21.496  1.00 35.44  ? 24  LEU B CB  1 
ATOM   2436  C  CG  . LEU B 1 24  ? 13.634  -28.512 22.257  1.00 43.77  ? 24  LEU B CG  1 
ATOM   2437  C  CD1 . LEU B 1 24  ? 12.620  -27.884 21.300  1.00 43.63  ? 24  LEU B CD1 1 
ATOM   2438  C  CD2 . LEU B 1 24  ? 13.246  -29.908 22.755  1.00 47.95  ? 24  LEU B CD2 1 
ATOM   2439  N  N   . VAL B 1 25  ? 16.508  -31.721 21.839  1.00 32.87  ? 25  VAL B N   1 
ATOM   2440  C  CA  . VAL B 1 25  ? 16.861  -32.948 21.143  1.00 32.80  ? 25  VAL B CA  1 
ATOM   2441  C  C   . VAL B 1 25  ? 15.713  -33.922 21.259  1.00 29.72  ? 25  VAL B C   1 
ATOM   2442  O  O   . VAL B 1 25  ? 15.233  -34.171 22.358  1.00 31.36  ? 25  VAL B O   1 
ATOM   2443  C  CB  . VAL B 1 25  ? 18.121  -33.628 21.670  1.00 34.67  ? 25  VAL B CB  1 
ATOM   2444  C  CG1 . VAL B 1 25  ? 18.386  -34.910 20.871  1.00 36.19  ? 25  VAL B CG1 1 
ATOM   2445  C  CG2 . VAL B 1 25  ? 19.296  -32.655 21.620  1.00 37.83  ? 25  VAL B CG2 1 
ATOM   2446  N  N   . VAL B 1 26  ? 15.253  -34.415 20.115  1.00 29.12  ? 26  VAL B N   1 
ATOM   2447  C  CA  . VAL B 1 26  ? 14.080  -35.269 20.104  1.00 31.81  ? 26  VAL B CA  1 
ATOM   2448  C  C   . VAL B 1 26  ? 14.342  -36.487 19.215  1.00 32.45  ? 26  VAL B C   1 
ATOM   2449  O  O   . VAL B 1 26  ? 15.219  -36.480 18.350  1.00 26.93  ? 26  VAL B O   1 
ATOM   2450  C  CB  . VAL B 1 26  ? 12.823  -34.500 19.656  1.00 33.42  ? 26  VAL B CB  1 
ATOM   2451  C  CG1 . VAL B 1 26  ? 12.569  -33.300 20.542  1.00 36.02  ? 26  VAL B CG1 1 
ATOM   2452  C  CG2 . VAL B 1 26  ? 12.908  -34.039 18.208  1.00 35.76  ? 26  VAL B CG2 1 
ATOM   2453  N  N   . THR B 1 27  ? 13.558  -37.543 19.458  1.00 35.57  ? 27  THR B N   1 
ATOM   2454  C  CA  . THR B 1 27  ? 13.507  -38.696 18.571  1.00 35.96  ? 27  THR B CA  1 
ATOM   2455  C  C   . THR B 1 27  ? 12.142  -38.737 17.917  1.00 32.21  ? 27  THR B C   1 
ATOM   2456  O  O   . THR B 1 27  ? 11.158  -38.287 18.488  1.00 38.23  ? 27  THR B O   1 
ATOM   2457  C  CB  . THR B 1 27  ? 13.774  -39.989 19.331  1.00 32.58  ? 27  THR B CB  1 
ATOM   2458  O  OG1 . THR B 1 27  ? 12.842  -40.014 20.412  1.00 35.77  ? 27  THR B OG1 1 
ATOM   2459  C  CG2 . THR B 1 27  ? 15.202  -40.051 19.806  1.00 32.85  ? 27  THR B CG2 1 
ATOM   2460  N  N   . ILE B 1 28  ? 12.124  -39.297 16.717  1.00 36.81  ? 28  ILE B N   1 
ATOM   2461  C  CA  . ILE B 1 28  ? 10.917  -39.343 15.913  1.00 39.59  ? 28  ILE B CA  1 
ATOM   2462  C  C   . ILE B 1 28  ? 10.211  -40.664 16.187  1.00 39.77  ? 28  ILE B C   1 
ATOM   2463  O  O   . ILE B 1 28  ? 10.770  -41.737 16.004  1.00 41.33  ? 28  ILE B O   1 
ATOM   2464  C  CB  . ILE B 1 28  ? 11.270  -39.195 14.426  1.00 38.99  ? 28  ILE B CB  1 
ATOM   2465  C  CG1 . ILE B 1 28  ? 12.130  -37.963 14.144  1.00 36.92  ? 28  ILE B CG1 1 
ATOM   2466  C  CG2 . ILE B 1 28  ? 9.997   -39.208 13.605  1.00 37.98  ? 28  ILE B CG2 1 
ATOM   2467  C  CD1 . ILE B 1 28  ? 12.726  -37.927 12.753  1.00 35.76  ? 28  ILE B CD1 1 
ATOM   2468  N  N   . ASP B 1 29  ? 8.949   -40.581 16.583  1.00 44.86  ? 29  ASP B N   1 
ATOM   2469  C  CA  . ASP B 1 29  ? 8.163   -41.774 16.828  1.00 46.69  ? 29  ASP B CA  1 
ATOM   2470  C  C   . ASP B 1 29  ? 7.844   -42.446 15.486  1.00 56.22  ? 29  ASP B C   1 
ATOM   2471  O  O   . ASP B 1 29  ? 7.931   -41.807 14.430  1.00 60.02  ? 29  ASP B O   1 
ATOM   2472  C  CB  . ASP B 1 29  ? 6.900   -41.392 17.584  1.00 50.33  ? 29  ASP B CB  1 
ATOM   2473  C  CG  . ASP B 1 29  ? 7.077   -40.748 18.961  1.00 46.91  ? 29  ASP B CG  1 
ATOM   2474  O  OD1 . ASP B 1 29  ? 8.250   -40.618 19.420  1.00 43.81  ? 29  ASP B OD1 1 
ATOM   2475  O  OD2 . ASP B 1 29  ? 6.034   -40.404 19.563  1.00 40.16  ? 29  ASP B OD2 1 
ATOM   2476  N  N   . SER B 1 30  ? 7.456   -43.737 15.513  1.00 58.26  ? 30  SER B N   1 
ATOM   2477  C  CA  . SER B 1 30  ? 7.004   -44.414 14.299  1.00 52.02  ? 30  SER B CA  1 
ATOM   2478  C  C   . SER B 1 30  ? 5.796   -43.668 13.762  1.00 51.84  ? 30  SER B C   1 
ATOM   2479  O  O   . SER B 1 30  ? 4.870   -43.366 14.522  1.00 47.46  ? 30  SER B O   1 
ATOM   2480  C  CB  . SER B 1 30  ? 6.607   -45.831 14.519  1.00 49.85  ? 30  SER B CB  1 
ATOM   2481  O  OG  . SER B 1 30  ? 7.500   -46.484 15.395  1.00 61.82  ? 30  SER B OG  1 
ATOM   2482  N  N   . GLY B 1 31  ? 5.815   -43.360 12.468  1.00 48.59  ? 31  GLY B N   1 
ATOM   2483  C  CA  . GLY B 1 31  ? 4.667   -42.707 11.865  1.00 49.51  ? 31  GLY B CA  1 
ATOM   2484  C  C   . GLY B 1 31  ? 4.809   -41.195 11.911  1.00 55.23  ? 31  GLY B C   1 
ATOM   2485  O  O   . GLY B 1 31  ? 4.065   -40.487 11.231  1.00 49.49  ? 31  GLY B O   1 
ATOM   2486  N  N   . GLY B 1 32  ? 5.836   -40.717 12.636  1.00 54.02  ? 32  GLY B N   1 
ATOM   2487  C  CA  . GLY B 1 32  ? 6.027   -39.292 12.844  1.00 51.93  ? 32  GLY B CA  1 
ATOM   2488  C  C   . GLY B 1 32  ? 6.636   -38.575 11.638  1.00 47.70  ? 32  GLY B C   1 
ATOM   2489  O  O   . GLY B 1 32  ? 6.666   -37.343 11.611  1.00 51.06  ? 32  GLY B O   1 
ATOM   2490  N  N   . GLU B 1 33  ? 7.089   -39.327 10.628  1.00 49.05  ? 33  GLU B N   1 
ATOM   2491  C  CA  . GLU B 1 33  ? 7.989   -38.798 9.610   1.00 50.93  ? 33  GLU B CA  1 
ATOM   2492  C  C   . GLU B 1 33  ? 7.327   -37.658 8.835   1.00 44.29  ? 33  GLU B C   1 
ATOM   2493  O  O   . GLU B 1 33  ? 7.985   -36.702 8.431   1.00 49.21  ? 33  GLU B O   1 
ATOM   2494  C  CB  . GLU B 1 33  ? 8.445   -39.932 8.674   1.00 55.44  ? 33  GLU B CB  1 
ATOM   2495  C  CG  . GLU B 1 33  ? 9.352   -41.000 9.295   1.00 48.26  ? 33  GLU B CG  1 
ATOM   2496  C  CD  . GLU B 1 33  ? 8.689   -42.058 10.162  1.00 49.74  ? 33  GLU B CD  1 
ATOM   2497  O  OE1 . GLU B 1 33  ? 7.434   -42.159 10.214  1.00 47.76  ? 33  GLU B OE1 1 
ATOM   2498  O  OE2 . GLU B 1 33  ? 9.437   -42.742 10.859  1.00 56.32  ? 33  GLU B OE2 1 
ATOM   2499  N  N   . ASP B 1 34  ? 6.029   -37.779 8.573   1.00 43.77  ? 34  ASP B N   1 
ATOM   2500  C  CA  . ASP B 1 34  ? 5.354   -36.802 7.745   1.00 49.90  ? 34  ASP B CA  1 
ATOM   2501  C  C   . ASP B 1 34  ? 5.214   -35.489 8.502   1.00 45.84  ? 34  ASP B C   1 
ATOM   2502  O  O   . ASP B 1 34  ? 5.453   -34.423 7.940   1.00 47.20  ? 34  ASP B O   1 
ATOM   2503  C  CB  . ASP B 1 34  ? 3.979   -37.263 7.289   1.00 55.33  ? 34  ASP B CB  1 
ATOM   2504  C  CG  . ASP B 1 34  ? 3.985   -38.277 6.159   1.00 60.68  ? 34  ASP B CG  1 
ATOM   2505  O  OD1 . ASP B 1 34  ? 4.843   -38.167 5.260   1.00 66.23  ? 34  ASP B OD1 1 
ATOM   2506  O  OD2 . ASP B 1 34  ? 3.121   -39.159 6.192   1.00 77.08  ? 34  ASP B OD2 1 
ATOM   2507  N  N   . THR B 1 35  ? 4.790   -35.564 9.764   1.00 38.36  ? 35  THR B N   1 
ATOM   2508  C  CA  . THR B 1 35  ? 4.658   -34.348 10.542  1.00 35.43  ? 35  THR B CA  1 
ATOM   2509  C  C   . THR B 1 35  ? 5.986   -33.603 10.575  1.00 35.15  ? 35  THR B C   1 
ATOM   2510  O  O   . THR B 1 35  ? 6.019   -32.396 10.421  1.00 34.31  ? 35  THR B O   1 
ATOM   2511  C  CB  . THR B 1 35  ? 4.228   -34.689 11.956  1.00 36.72  ? 35  THR B CB  1 
ATOM   2512  O  OG1 . THR B 1 35  ? 3.000   -35.379 11.809  1.00 38.08  ? 35  THR B OG1 1 
ATOM   2513  C  CG2 . THR B 1 35  ? 4.080   -33.437 12.796  1.00 37.46  ? 35  THR B CG2 1 
ATOM   2514  N  N   . VAL B 1 36  ? 7.072   -34.347 10.784  1.00 35.39  ? 36  VAL B N   1 
ATOM   2515  C  CA  . VAL B 1 36  ? 8.412   -33.799 10.849  1.00 34.79  ? 36  VAL B CA  1 
ATOM   2516  C  C   . VAL B 1 36  ? 8.761   -33.129 9.537   1.00 37.08  ? 36  VAL B C   1 
ATOM   2517  O  O   . VAL B 1 36  ? 9.272   -32.023 9.562   1.00 34.56  ? 36  VAL B O   1 
ATOM   2518  C  CB  . VAL B 1 36  ? 9.463   -34.870 11.200  1.00 38.22  ? 36  VAL B CB  1 
ATOM   2519  C  CG1 . VAL B 1 36  ? 10.906  -34.389 11.002  1.00 38.75  ? 36  VAL B CG1 1 
ATOM   2520  C  CG2 . VAL B 1 36  ? 9.248   -35.390 12.618  1.00 40.25  ? 36  VAL B CG2 1 
ATOM   2521  N  N   . ARG B 1 37  ? 8.538   -33.805 8.406   1.00 42.44  ? 37  ARG B N   1 
ATOM   2522  C  CA  . ARG B 1 37  ? 8.850   -33.229 7.107   1.00 41.20  ? 37  ARG B CA  1 
ATOM   2523  C  C   . ARG B 1 37  ? 8.145   -31.874 6.914   1.00 42.75  ? 37  ARG B C   1 
ATOM   2524  O  O   . ARG B 1 37  ? 8.723   -30.942 6.358   1.00 35.12  ? 37  ARG B O   1 
ATOM   2525  C  CB  . ARG B 1 37  ? 8.472   -34.217 5.998   1.00 40.73  ? 37  ARG B CB  1 
ATOM   2526  C  CG  . ARG B 1 37  ? 9.626   -35.001 5.391   1.00 46.13  ? 37  ARG B CG  1 
ATOM   2527  C  CD  . ARG B 1 37  ? 9.329   -35.607 4.009   1.00 45.88  ? 37  ARG B CD  1 
ATOM   2528  N  NE  . ARG B 1 37  ? 9.100   -37.047 4.176   1.00 45.54  ? 37  ARG B NE  1 
ATOM   2529  N  N   . ASP B 1 38  ? 6.876   -31.764 7.317   1.00 41.77  ? 38  ASP B N   1 
ATOM   2530  C  CA  . ASP B 1 38  ? 6.147   -30.510 7.153   1.00 45.17  ? 38  ASP B CA  1 
ATOM   2531  C  C   . ASP B 1 38  ? 6.771   -29.393 7.973   1.00 40.88  ? 38  ASP B C   1 
ATOM   2532  O  O   . ASP B 1 38  ? 6.907   -28.278 7.484   1.00 39.10  ? 38  ASP B O   1 
ATOM   2533  C  CB  . ASP B 1 38  ? 4.711   -30.562 7.638   1.00 60.51  ? 38  ASP B CB  1 
ATOM   2534  C  CG  . ASP B 1 38  ? 3.736   -31.141 6.625   1.00 69.59  ? 38  ASP B CG  1 
ATOM   2535  O  OD1 . ASP B 1 38  ? 3.868   -30.787 5.438   1.00 76.50  ? 38  ASP B OD1 1 
ATOM   2536  O  OD2 . ASP B 1 38  ? 2.852   -31.927 7.032   1.00 87.34  ? 38  ASP B OD2 1 
ATOM   2537  N  N   . LEU B 1 39  ? 7.089   -29.708 9.228   1.00 36.73  ? 39  LEU B N   1 
ATOM   2538  C  CA  . LEU B 1 39  ? 7.726   -28.762 10.123  1.00 37.61  ? 39  LEU B CA  1 
ATOM   2539  C  C   . LEU B 1 39  ? 9.057   -28.283 9.553   1.00 36.06  ? 39  LEU B C   1 
ATOM   2540  O  O   . LEU B 1 39  ? 9.357   -27.100 9.618   1.00 36.01  ? 39  LEU B O   1 
ATOM   2541  C  CB  . LEU B 1 39  ? 7.870   -29.418 11.499  1.00 40.34  ? 39  LEU B CB  1 
ATOM   2542  C  CG  . LEU B 1 39  ? 8.412   -28.576 12.657  1.00 36.66  ? 39  LEU B CG  1 
ATOM   2543  C  CD1 . LEU B 1 39  ? 9.923   -28.521 12.612  1.00 35.30  ? 39  LEU B CD1 1 
ATOM   2544  C  CD2 . LEU B 1 39  ? 7.804   -27.173 12.665  1.00 37.68  ? 39  LEU B CD2 1 
ATOM   2545  N  N   . LEU B 1 40  ? 9.854   -29.179 8.977   1.00 32.26  ? 40  LEU B N   1 
ATOM   2546  C  CA  . LEU B 1 40  ? 11.173  -28.777 8.522   1.00 35.85  ? 40  LEU B CA  1 
ATOM   2547  C  C   . LEU B 1 40  ? 11.056  -27.748 7.413   1.00 36.20  ? 40  LEU B C   1 
ATOM   2548  O  O   . LEU B 1 40  ? 11.921  -26.889 7.256   1.00 35.58  ? 40  LEU B O   1 
ATOM   2549  C  CB  . LEU B 1 40  ? 12.005  -29.963 8.062   1.00 40.10  ? 40  LEU B CB  1 
ATOM   2550  C  CG  . LEU B 1 40  ? 12.417  -30.934 9.172   1.00 48.49  ? 40  LEU B CG  1 
ATOM   2551  C  CD1 . LEU B 1 40  ? 13.200  -32.076 8.562   1.00 53.07  ? 40  LEU B CD1 1 
ATOM   2552  C  CD2 . LEU B 1 40  ? 13.253  -30.271 10.244  1.00 53.50  ? 40  LEU B CD2 1 
ATOM   2553  N  N   . SER B 1 41  ? 9.985   -27.836 6.632   1.00 38.94  ? 41  SER B N   1 
ATOM   2554  C  CA  . SER B 1 41  ? 9.824   -26.914 5.518   1.00 42.47  ? 41  SER B CA  1 
ATOM   2555  C  C   . SER B 1 41  ? 9.331   -25.564 6.022   1.00 39.18  ? 41  SER B C   1 
ATOM   2556  O  O   . SER B 1 41  ? 9.361   -24.596 5.291   1.00 40.64  ? 41  SER B O   1 
ATOM   2557  C  CB  . SER B 1 41  ? 8.897   -27.471 4.455   1.00 45.84  ? 41  SER B CB  1 
ATOM   2558  O  OG  . SER B 1 41  ? 7.573   -27.576 4.973   1.00 44.58  ? 41  SER B OG  1 
ATOM   2559  N  N   . ASP B 1 42  ? 8.891   -25.483 7.276   1.00 37.72  ? 42  ASP B N   1 
ATOM   2560  C  CA  . ASP B 1 42  ? 8.326   -24.250 7.782   1.00 40.54  ? 42  ASP B CA  1 
ATOM   2561  C  C   . ASP B 1 42  ? 9.211   -23.591 8.834   1.00 38.40  ? 42  ASP B C   1 
ATOM   2562  O  O   . ASP B 1 42  ? 8.896   -22.512 9.322   1.00 34.25  ? 42  ASP B O   1 
ATOM   2563  C  CB  . ASP B 1 42  ? 6.957   -24.534 8.376   1.00 45.23  ? 42  ASP B CB  1 
ATOM   2564  C  CG  . ASP B 1 42  ? 5.805   -24.673 7.400   1.00 43.54  ? 42  ASP B CG  1 
ATOM   2565  O  OD1 . ASP B 1 42  ? 5.874   -24.082 6.292   1.00 44.61  ? 42  ASP B OD1 1 
ATOM   2566  O  OD2 . ASP B 1 42  ? 4.860   -25.373 7.778   1.00 44.94  ? 42  ASP B OD2 1 
ATOM   2567  N  N   . VAL B 1 43  ? 10.287  -24.248 9.253   1.00 43.55  ? 43  VAL B N   1 
ATOM   2568  C  CA  . VAL B 1 43  ? 10.973  -23.805 10.454  1.00 41.45  ? 43  VAL B CA  1 
ATOM   2569  C  C   . VAL B 1 43  ? 11.606  -22.431 10.191  1.00 37.07  ? 43  VAL B C   1 
ATOM   2570  O  O   . VAL B 1 43  ? 11.596  -21.593 11.067  1.00 36.19  ? 43  VAL B O   1 
ATOM   2571  C  CB  . VAL B 1 43  ? 11.994  -24.862 10.913  1.00 46.39  ? 43  VAL B CB  1 
ATOM   2572  C  CG1 . VAL B 1 43  ? 13.173  -24.950 9.948   1.00 50.09  ? 43  VAL B CG1 1 
ATOM   2573  C  CG2 . VAL B 1 43  ? 12.476  -24.588 12.323  1.00 49.87  ? 43  VAL B CG2 1 
ATOM   2574  N  N   . ALA B 1 44  ? 12.093  -22.146 8.974   1.00 32.79  ? 44  ALA B N   1 
ATOM   2575  C  CA  . ALA B 1 44  ? 12.626  -20.820 8.674   1.00 31.02  ? 44  ALA B CA  1 
ATOM   2576  C  C   . ALA B 1 44  ? 11.570  -19.730 8.840   1.00 29.61  ? 44  ALA B C   1 
ATOM   2577  O  O   . ALA B 1 44  ? 11.894  -18.649 9.316   1.00 27.58  ? 44  ALA B O   1 
ATOM   2578  C  CB  . ALA B 1 44  ? 13.177  -20.763 7.284   1.00 30.96  ? 44  ALA B CB  1 
ATOM   2579  N  N   . SER B 1 45  ? 10.308  -20.014 8.460   1.00 29.46  ? 45  SER B N   1 
ATOM   2580  C  CA  . SER B 1 45  ? 9.310   -18.960 8.510   1.00 32.08  ? 45  SER B CA  1 
ATOM   2581  C  C   . SER B 1 45  ? 8.779   -18.785 9.930   1.00 29.97  ? 45  SER B C   1 
ATOM   2582  O  O   . SER B 1 45  ? 8.403   -17.677 10.291  1.00 29.67  ? 45  SER B O   1 
ATOM   2583  C  CB  . SER B 1 45  ? 8.232   -19.116 7.485   1.00 29.12  ? 45  SER B CB  1 
ATOM   2584  O  OG  . SER B 1 45  ? 7.701   -20.408 7.563   1.00 32.08  ? 45  SER B OG  1 
ATOM   2585  N  N   . LEU B 1 46  ? 8.860   -19.832 10.758  1.00 27.57  ? 46  LEU B N   1 
ATOM   2586  C  CA  . LEU B 1 46  ? 8.606   -19.673 12.180  1.00 27.46  ? 46  LEU B CA  1 
ATOM   2587  C  C   . LEU B 1 46  ? 9.683   -18.797 12.826  1.00 31.21  ? 46  LEU B C   1 
ATOM   2588  O  O   . LEU B 1 46  ? 9.400   -17.962 13.702  1.00 29.99  ? 46  LEU B O   1 
ATOM   2589  C  CB  . LEU B 1 46  ? 8.512   -21.056 12.821  1.00 27.57  ? 46  LEU B CB  1 
ATOM   2590  C  CG  . LEU B 1 46  ? 7.282   -21.852 12.395  1.00 28.80  ? 46  LEU B CG  1 
ATOM   2591  C  CD1 . LEU B 1 46  ? 7.330   -23.240 12.974  1.00 32.94  ? 46  LEU B CD1 1 
ATOM   2592  C  CD2 . LEU B 1 46  ? 6.018   -21.148 12.849  1.00 31.72  ? 46  LEU B CD2 1 
ATOM   2593  N  N   . GLU B 1 47  ? 10.940  -18.990 12.407  1.00 28.36  ? 47  GLU B N   1 
ATOM   2594  C  CA  . GLU B 1 47  ? 12.040  -18.195 12.914  1.00 27.46  ? 47  GLU B CA  1 
ATOM   2595  C  C   . GLU B 1 47  ? 11.713  -16.726 12.630  1.00 26.69  ? 47  GLU B C   1 
ATOM   2596  O  O   . GLU B 1 47  ? 11.780  -15.910 13.536  1.00 26.20  ? 47  GLU B O   1 
ATOM   2597  C  CB  . GLU B 1 47  ? 13.309  -18.814 12.344  1.00 26.81  ? 47  GLU B CB  1 
ATOM   2598  C  CG  . GLU B 1 47  ? 14.531  -17.907 12.285  1.00 32.40  ? 47  GLU B CG  1 
ATOM   2599  C  CD  . GLU B 1 47  ? 15.766  -18.684 11.915  1.00 34.91  ? 47  GLU B CD  1 
ATOM   2600  O  OE1 . GLU B 1 47  ? 15.746  -19.883 11.587  1.00 42.37  ? 47  GLU B OE1 1 
ATOM   2601  O  OE2 . GLU B 1 47  ? 16.796  -18.081 12.054  1.00 38.59  ? 47  GLU B OE2 1 
ATOM   2602  N  N   . ARG B 1 48  ? 11.284  -16.391 11.408  1.00 26.79  ? 48  ARG B N   1 
ATOM   2603  C  CA  . ARG B 1 48  ? 10.943  -15.004 11.104  1.00 28.38  ? 48  ARG B CA  1 
ATOM   2604  C  C   . ARG B 1 48  ? 9.704   -14.525 11.848  1.00 25.86  ? 48  ARG B C   1 
ATOM   2605  O  O   . ARG B 1 48  ? 9.695   -13.422 12.320  1.00 23.81  ? 48  ARG B O   1 
ATOM   2606  C  CB  . ARG B 1 48  ? 10.705  -14.771 9.609   1.00 34.08  ? 48  ARG B CB  1 
ATOM   2607  C  CG  . ARG B 1 48  ? 12.046  -14.956 8.922   1.00 39.17  ? 48  ARG B CG  1 
ATOM   2608  C  CD  . ARG B 1 48  ? 12.003  -14.401 7.529   1.00 44.73  ? 48  ARG B CD  1 
ATOM   2609  N  NE  . ARG B 1 48  ? 11.042  -15.147 6.712   1.00 43.11  ? 48  ARG B NE  1 
ATOM   2610  C  CZ  . ARG B 1 48  ? 11.227  -16.358 6.175   1.00 43.03  ? 48  ARG B CZ  1 
ATOM   2611  N  NH1 . ARG B 1 48  ? 12.376  -17.002 6.267   1.00 43.19  ? 48  ARG B NH1 1 
ATOM   2612  N  NH2 . ARG B 1 48  ? 10.252  -16.966 5.535   1.00 42.35  ? 48  ARG B NH2 1 
ATOM   2613  N  N   . ALA B 1 49  ? 8.650   -15.333 11.954  1.00 26.03  ? 49  ALA B N   1 
ATOM   2614  C  CA  . ALA B 1 49  ? 7.433   -14.914 12.629  1.00 24.31  ? 49  ALA B CA  1 
ATOM   2615  C  C   . ALA B 1 49  ? 7.703   -14.444 14.045  1.00 25.39  ? 49  ALA B C   1 
ATOM   2616  O  O   . ALA B 1 49  ? 7.241   -13.370 14.448  1.00 26.86  ? 49  ALA B O   1 
ATOM   2617  C  CB  . ALA B 1 49  ? 6.493   -16.055 12.665  1.00 24.33  ? 49  ALA B CB  1 
ATOM   2618  N  N   . VAL B 1 50  ? 8.453   -15.277 14.780  1.00 25.40  ? 50  VAL B N   1 
ATOM   2619  C  CA  . VAL B 1 50  ? 8.738   -15.011 16.182  1.00 26.08  ? 50  VAL B CA  1 
ATOM   2620  C  C   . VAL B 1 50  ? 9.765   -13.895 16.314  1.00 26.01  ? 50  VAL B C   1 
ATOM   2621  O  O   . VAL B 1 50  ? 9.702   -13.075 17.214  1.00 26.85  ? 50  VAL B O   1 
ATOM   2622  C  CB  . VAL B 1 50  ? 9.244   -16.255 16.933  1.00 30.24  ? 50  VAL B CB  1 
ATOM   2623  C  CG1 . VAL B 1 50  ? 9.629   -15.941 18.369  1.00 29.34  ? 50  VAL B CG1 1 
ATOM   2624  C  CG2 . VAL B 1 50  ? 8.228   -17.391 16.921  1.00 33.78  ? 50  VAL B CG2 1 
ATOM   2625  N  N   . GLY B 1 51  ? 10.727  -13.862 15.414  1.00 25.16  ? 51  GLY B N   1 
ATOM   2626  C  CA  . GLY B 1 51  ? 11.874  -12.999 15.607  1.00 27.67  ? 51  GLY B CA  1 
ATOM   2627  C  C   . GLY B 1 51  ? 11.747  -11.620 14.972  1.00 29.69  ? 51  GLY B C   1 
ATOM   2628  O  O   . GLY B 1 51  ? 12.333  -10.670 15.476  1.00 29.70  ? 51  GLY B O   1 
ATOM   2629  N  N   . PHE B 1 52  ? 11.024  -11.488 13.858  1.00 33.68  ? 52  PHE B N   1 
ATOM   2630  C  CA  . PHE B 1 52  ? 11.111  -10.260 13.082  1.00 33.96  ? 52  PHE B CA  1 
ATOM   2631  C  C   . PHE B 1 52  ? 10.660  -9.050  13.918  1.00 36.17  ? 52  PHE B C   1 
ATOM   2632  O  O   . PHE B 1 52  ? 11.297  -7.998  13.898  1.00 31.91  ? 52  PHE B O   1 
ATOM   2633  C  CB  . PHE B 1 52  ? 10.292  -10.353 11.807  1.00 32.98  ? 52  PHE B CB  1 
ATOM   2634  C  CG  . PHE B 1 52  ? 10.339  -9.027  11.089  1.00 34.78  ? 52  PHE B CG  1 
ATOM   2635  C  CD1 . PHE B 1 52  ? 11.456  -8.689  10.354  1.00 36.10  ? 52  PHE B CD1 1 
ATOM   2636  C  CD2 . PHE B 1 52  ? 9.313   -8.105  11.227  1.00 36.20  ? 52  PHE B CD2 1 
ATOM   2637  C  CE1 . PHE B 1 52  ? 11.516  -7.466  9.711   1.00 40.99  ? 52  PHE B CE1 1 
ATOM   2638  C  CE2 . PHE B 1 52  ? 9.376   -6.882  10.581  1.00 40.83  ? 52  PHE B CE2 1 
ATOM   2639  C  CZ  . PHE B 1 52  ? 10.467  -6.571  9.803   1.00 41.31  ? 52  PHE B CZ  1 
ATOM   2640  N  N   . ARG B 1 53  ? 9.593   -9.220  14.705  1.00 38.28  ? 53  ARG B N   1 
ATOM   2641  C  CA  . ARG B 1 53  ? 9.045   -8.105  15.463  1.00 35.75  ? 53  ARG B CA  1 
ATOM   2642  C  C   . ARG B 1 53  ? 9.965   -7.692  16.618  1.00 33.01  ? 53  ARG B C   1 
ATOM   2643  O  O   . ARG B 1 53  ? 9.746   -6.649  17.243  1.00 34.37  ? 53  ARG B O   1 
ATOM   2644  C  CB  . ARG B 1 53  ? 7.602   -8.400  15.890  1.00 37.13  ? 53  ARG B CB  1 
ATOM   2645  C  CG  . ARG B 1 53  ? 7.428   -9.312  17.092  1.00 44.12  ? 53  ARG B CG  1 
ATOM   2646  C  CD  . ARG B 1 53  ? 6.026   -9.372  17.709  1.00 45.76  ? 53  ARG B CD  1 
ATOM   2647  N  NE  . ARG B 1 53  ? 5.765   -10.746 18.159  1.00 46.93  ? 53  ARG B NE  1 
ATOM   2648  C  CZ  . ARG B 1 53  ? 5.916   -11.777 17.335  1.00 51.52  ? 53  ARG B CZ  1 
ATOM   2649  N  NH1 . ARG B 1 53  ? 6.194   -11.542 16.054  1.00 61.71  ? 53  ARG B NH1 1 
ATOM   2650  N  NH2 . ARG B 1 53  ? 5.832   -13.008 17.795  1.00 49.56  ? 53  ARG B NH2 1 
ATOM   2651  N  N   . ALA B 1 54  ? 10.985  -8.502  16.937  1.00 33.64  ? 54  ALA B N   1 
ATOM   2652  C  CA  . ALA B 1 54  ? 11.935  -8.188  18.010  1.00 33.90  ? 54  ALA B CA  1 
ATOM   2653  C  C   . ALA B 1 54  ? 13.246  -7.633  17.471  1.00 36.13  ? 54  ALA B C   1 
ATOM   2654  O  O   . ALA B 1 54  ? 14.181  -7.556  18.248  1.00 37.35  ? 54  ALA B O   1 
ATOM   2655  C  CB  . ALA B 1 54  ? 12.214  -9.420  18.858  1.00 30.73  ? 54  ALA B CB  1 
ATOM   2656  N  N   . GLN B 1 55  ? 13.302  -7.243  16.181  1.00 45.77  ? 55  GLN B N   1 
ATOM   2657  C  CA  . GLN B 1 55  ? 14.480  -6.638  15.589  1.00 51.17  ? 55  GLN B CA  1 
ATOM   2658  C  C   . GLN B 1 55  ? 14.760  -5.277  16.227  1.00 56.66  ? 55  GLN B C   1 
ATOM   2659  O  O   . GLN B 1 55  ? 13.838  -4.612  16.703  1.00 47.00  ? 55  GLN B O   1 
ATOM   2660  C  CB  . GLN B 1 55  ? 14.435  -6.402  14.072  1.00 55.51  ? 55  GLN B CB  1 
ATOM   2661  C  CG  . GLN B 1 55  ? 14.699  -7.617  13.185  1.00 60.29  ? 55  GLN B CG  1 
ATOM   2662  C  CD  . GLN B 1 55  ? 15.725  -8.620  13.689  1.00 68.45  ? 55  GLN B CD  1 
ATOM   2663  O  OE1 . GLN B 1 55  ? 16.194  -8.629  14.841  1.00 76.68  ? 55  GLN B OE1 1 
ATOM   2664  N  NE2 . GLN B 1 55  ? 16.053  -9.548  12.803  1.00 70.24  ? 55  GLN B NE2 1 
ATOM   2665  N  N   . PRO B 1 56  ? 16.048  -4.843  16.262  1.00 72.30  ? 56  PRO B N   1 
ATOM   2666  C  CA  . PRO B 1 56  ? 17.189  -5.705  15.916  1.00 73.39  ? 56  PRO B CA  1 
ATOM   2667  C  C   . PRO B 1 56  ? 17.956  -6.294  17.114  1.00 58.79  ? 56  PRO B C   1 
ATOM   2668  O  O   . PRO B 1 56  ? 18.854  -7.099  16.922  1.00 56.07  ? 56  PRO B O   1 
ATOM   2669  C  CB  . PRO B 1 56  ? 18.044  -4.751  15.035  1.00 76.20  ? 56  PRO B CB  1 
ATOM   2670  C  CG  . PRO B 1 56  ? 17.600  -3.341  15.452  1.00 80.24  ? 56  PRO B CG  1 
ATOM   2671  C  CD  . PRO B 1 56  ? 16.488  -3.469  16.522  1.00 75.77  ? 56  PRO B CD  1 
ATOM   2672  N  N   . ASP B 1 57  ? 17.541  -5.980  18.347  1.00 52.37  ? 57  ASP B N   1 
ATOM   2673  C  CA  . ASP B 1 57  ? 18.138  -6.592  19.526  1.00 53.52  ? 57  ASP B CA  1 
ATOM   2674  C  C   . ASP B 1 57  ? 17.875  -8.096  19.653  1.00 45.94  ? 57  ASP B C   1 
ATOM   2675  O  O   . ASP B 1 57  ? 18.552  -8.729  20.445  1.00 46.86  ? 57  ASP B O   1 
ATOM   2676  C  CB  . ASP B 1 57  ? 17.555  -6.091  20.839  1.00 58.67  ? 57  ASP B CB  1 
ATOM   2677  C  CG  . ASP B 1 57  ? 17.406  -4.590  20.939  1.00 67.86  ? 57  ASP B CG  1 
ATOM   2678  O  OD1 . ASP B 1 57  ? 18.450  -3.898  20.896  1.00 62.03  ? 57  ASP B OD1 1 
ATOM   2679  O  OD2 . ASP B 1 57  ? 16.244  -4.150  21.051  1.00 76.80  ? 57  ASP B OD2 1 
ATOM   2680  N  N   . GLY B 1 58  ? 16.882  -8.678  18.963  1.00 36.51  ? 58  GLY B N   1 
ATOM   2681  C  CA  . GLY B 1 58  ? 16.407  -10.011 19.316  1.00 33.90  ? 58  GLY B CA  1 
ATOM   2682  C  C   . GLY B 1 58  ? 17.445  -11.078 18.967  1.00 34.36  ? 58  GLY B C   1 
ATOM   2683  O  O   . GLY B 1 58  ? 17.766  -11.948 19.771  1.00 27.51  ? 58  GLY B O   1 
ATOM   2684  N  N   . ARG B 1 59  ? 17.947  -11.015 17.734  1.00 36.56  ? 59  ARG B N   1 
ATOM   2685  C  CA  . ARG B 1 59  ? 19.022  -11.891 17.290  1.00 39.21  ? 59  ARG B CA  1 
ATOM   2686  C  C   . ARG B 1 59  ? 18.632  -13.357 17.431  1.00 37.36  ? 59  ARG B C   1 
ATOM   2687  O  O   . ARG B 1 59  ? 19.475  -14.208 17.699  1.00 37.70  ? 59  ARG B O   1 
ATOM   2688  C  CB  . ARG B 1 59  ? 20.329  -11.567 18.008  1.00 47.27  ? 59  ARG B CB  1 
ATOM   2689  C  CG  . ARG B 1 59  ? 20.821  -10.193 17.555  1.00 58.12  ? 59  ARG B CG  1 
ATOM   2690  C  CD  . ARG B 1 59  ? 22.287  -9.882  17.366  1.00 78.11  ? 59  ARG B CD  1 
ATOM   2691  N  NE  . ARG B 1 59  ? 22.794  -9.196  18.560  1.00 87.85  ? 59  ARG B NE  1 
ATOM   2692  C  CZ  . ARG B 1 59  ? 23.037  -9.762  19.734  1.00 80.93  ? 59  ARG B CZ  1 
ATOM   2693  N  NH1 . ARG B 1 59  ? 23.268  -11.059 19.856  1.00 86.65  ? 59  ARG B NH1 1 
ATOM   2694  N  NH2 . ARG B 1 59  ? 23.115  -8.988  20.788  1.00 77.73  ? 59  ARG B NH2 1 
ATOM   2695  N  N   . LEU B 1 60  ? 17.351  -13.639 17.178  1.00 34.60  ? 60  LEU B N   1 
ATOM   2696  C  CA  . LEU B 1 60  ? 16.815  -14.987 17.264  1.00 32.20  ? 60  LEU B CA  1 
ATOM   2697  C  C   . LEU B 1 60  ? 17.231  -15.780 16.035  1.00 30.48  ? 60  LEU B C   1 
ATOM   2698  O  O   . LEU B 1 60  ? 17.095  -15.270 14.947  1.00 28.23  ? 60  LEU B O   1 
ATOM   2699  C  CB  . LEU B 1 60  ? 15.299  -14.920 17.390  1.00 27.09  ? 60  LEU B CB  1 
ATOM   2700  C  CG  . LEU B 1 60  ? 14.621  -16.281 17.408  1.00 27.03  ? 60  LEU B CG  1 
ATOM   2701  C  CD1 . LEU B 1 60  ? 14.864  -17.040 18.696  1.00 28.31  ? 60  LEU B CD1 1 
ATOM   2702  C  CD2 . LEU B 1 60  ? 13.160  -16.102 17.176  1.00 29.91  ? 60  LEU B CD2 1 
ATOM   2703  N  N   . SER B 1 61  ? 17.728  -17.002 16.221  1.00 31.19  ? 61  SER B N   1 
ATOM   2704  C  CA  . SER B 1 61  ? 18.049  -17.901 15.122  1.00 33.46  ? 61  SER B CA  1 
ATOM   2705  C  C   . SER B 1 61  ? 17.722  -19.310 15.576  1.00 29.79  ? 61  SER B C   1 
ATOM   2706  O  O   . SER B 1 61  ? 17.789  -19.616 16.764  1.00 30.03  ? 61  SER B O   1 
ATOM   2707  C  CB  . SER B 1 61  ? 19.530  -17.823 14.738  1.00 34.63  ? 61  SER B CB  1 
ATOM   2708  O  OG  . SER B 1 61  ? 20.346  -18.650 15.569  1.00 44.94  ? 61  SER B OG  1 
ATOM   2709  N  N   . CYS B 1 62  ? 17.444  -20.193 14.629  1.00 28.53  ? 62  CYS B N   1 
ATOM   2710  C  CA  . CYS B 1 62  ? 17.288  -21.596 14.947  1.00 27.75  ? 62  CYS B CA  1 
ATOM   2711  C  C   . CYS B 1 62  ? 18.159  -22.379 13.982  1.00 28.23  ? 62  CYS B C   1 
ATOM   2712  O  O   . CYS B 1 62  ? 18.095  -22.144 12.795  1.00 27.62  ? 62  CYS B O   1 
ATOM   2713  C  CB  . CYS B 1 62  ? 15.843  -22.038 14.806  1.00 27.77  ? 62  CYS B CB  1 
ATOM   2714  S  SG  . CYS B 1 62  ? 15.638  -23.798 15.148  1.00 30.67  ? 62  CYS B SG  1 
ATOM   2715  N  N   . VAL B 1 63  ? 19.022  -23.261 14.468  1.00 26.76  ? 63  VAL B N   1 
ATOM   2716  C  CA  . VAL B 1 63  ? 19.656  -24.167 13.538  1.00 27.58  ? 63  VAL B CA  1 
ATOM   2717  C  C   . VAL B 1 63  ? 19.120  -25.585 13.771  1.00 30.54  ? 63  VAL B C   1 
ATOM   2718  O  O   . VAL B 1 63  ? 19.037  -26.056 14.898  1.00 26.25  ? 63  VAL B O   1 
ATOM   2719  C  CB  . VAL B 1 63  ? 21.174  -24.089 13.677  1.00 31.20  ? 63  VAL B CB  1 
ATOM   2720  C  CG1 . VAL B 1 63  ? 21.874  -25.091 12.767  1.00 34.21  ? 63  VAL B CG1 1 
ATOM   2721  C  CG2 . VAL B 1 63  ? 21.675  -22.678 13.408  1.00 32.47  ? 63  VAL B CG2 1 
ATOM   2722  N  N   . THR B 1 64  ? 18.713  -26.237 12.677  1.00 27.63  ? 64  THR B N   1 
ATOM   2723  C  CA  . THR B 1 64  ? 18.055  -27.521 12.721  1.00 29.84  ? 64  THR B CA  1 
ATOM   2724  C  C   . THR B 1 64  ? 19.015  -28.569 12.190  1.00 32.14  ? 64  THR B C   1 
ATOM   2725  O  O   . THR B 1 64  ? 19.571  -28.405 11.110  1.00 32.59  ? 64  THR B O   1 
ATOM   2726  C  CB  . THR B 1 64  ? 16.801  -27.494 11.866  1.00 30.20  ? 64  THR B CB  1 
ATOM   2727  O  OG1 . THR B 1 64  ? 15.983  -26.473 12.418  1.00 33.24  ? 64  THR B OG1 1 
ATOM   2728  C  CG2 . THR B 1 64  ? 16.025  -28.792 11.970  1.00 35.88  ? 64  THR B CG2 1 
ATOM   2729  N  N   . GLY B 1 65  ? 19.168  -29.657 12.953  1.00 30.25  ? 65  GLY B N   1 
ATOM   2730  C  CA  . GLY B 1 65  ? 20.056  -30.725 12.563  1.00 28.67  ? 65  GLY B CA  1 
ATOM   2731  C  C   . GLY B 1 65  ? 19.331  -32.052 12.596  1.00 29.42  ? 65  GLY B C   1 
ATOM   2732  O  O   . GLY B 1 65  ? 18.403  -32.243 13.380  1.00 31.25  ? 65  GLY B O   1 
ATOM   2733  N  N   . ILE B 1 66  ? 19.833  -32.968 11.757  1.00 32.99  ? 66  ILE B N   1 
ATOM   2734  C  CA  . ILE B 1 66  ? 19.226  -34.271 11.563  1.00 33.46  ? 66  ILE B CA  1 
ATOM   2735  C  C   . ILE B 1 66  ? 20.290  -35.350 11.755  1.00 31.78  ? 66  ILE B C   1 
ATOM   2736  O  O   . ILE B 1 66  ? 21.397  -35.225 11.239  1.00 30.49  ? 66  ILE B O   1 
ATOM   2737  C  CB  . ILE B 1 66  ? 18.591  -34.309 10.170  1.00 33.53  ? 66  ILE B CB  1 
ATOM   2738  C  CG1 . ILE B 1 66  ? 17.543  -33.221 10.025  1.00 32.41  ? 66  ILE B CG1 1 
ATOM   2739  C  CG2 . ILE B 1 66  ? 18.014  -35.699 9.877   1.00 38.16  ? 66  ILE B CG2 1 
ATOM   2740  C  CD1 . ILE B 1 66  ? 17.320  -32.821 8.595   1.00 33.89  ? 66  ILE B CD1 1 
ATOM   2741  N  N   . GLY B 1 67  ? 19.935  -36.402 12.495  1.00 32.47  ? 67  GLY B N   1 
ATOM   2742  C  CA  . GLY B 1 67  ? 20.853  -37.497 12.772  1.00 38.16  ? 67  GLY B CA  1 
ATOM   2743  C  C   . GLY B 1 67  ? 20.927  -38.500 11.620  1.00 40.09  ? 67  GLY B C   1 
ATOM   2744  O  O   . GLY B 1 67  ? 20.125  -38.474 10.699  1.00 39.61  ? 67  GLY B O   1 
ATOM   2745  N  N   . SER B 1 68  ? 21.879  -39.415 11.737  1.00 38.46  ? 68  SER B N   1 
ATOM   2746  C  CA  . SER B 1 68  ? 22.179  -40.427 10.736  1.00 39.72  ? 68  SER B CA  1 
ATOM   2747  C  C   . SER B 1 68  ? 20.996  -41.374 10.475  1.00 40.16  ? 68  SER B C   1 
ATOM   2748  O  O   . SER B 1 68  ? 20.568  -41.515 9.345   1.00 38.40  ? 68  SER B O   1 
ATOM   2749  C  CB  . SER B 1 68  ? 23.388  -41.183 11.209  1.00 38.28  ? 68  SER B CB  1 
ATOM   2750  O  OG  . SER B 1 68  ? 23.923  -41.949 10.168  1.00 34.03  ? 68  SER B OG  1 
ATOM   2751  N  N   . GLU B 1 69  ? 20.460  -42.000 11.528  1.00 39.70  ? 69  GLU B N   1 
ATOM   2752  C  CA  . GLU B 1 69  ? 19.337  -42.905 11.410  1.00 40.57  ? 69  GLU B CA  1 
ATOM   2753  C  C   . GLU B 1 69  ? 18.064  -42.216 10.938  1.00 40.88  ? 69  GLU B C   1 
ATOM   2754  O  O   . GLU B 1 69  ? 17.262  -42.797 10.201  1.00 37.79  ? 69  GLU B O   1 
ATOM   2755  C  CB  . GLU B 1 69  ? 18.948  -43.443 12.778  1.00 49.95  ? 69  GLU B CB  1 
ATOM   2756  C  CG  . GLU B 1 69  ? 19.957  -44.393 13.408  1.00 61.44  ? 69  GLU B CG  1 
ATOM   2757  C  CD  . GLU B 1 69  ? 19.282  -45.327 14.408  1.00 72.27  ? 69  GLU B CD  1 
ATOM   2758  O  OE1 . GLU B 1 69  ? 18.010  -45.442 14.565  1.00 73.38  ? 69  GLU B OE1 1 
ATOM   2759  O  OE2 . GLU B 1 69  ? 20.129  -45.960 15.071  1.00 72.79  ? 69  GLU B OE2 1 
ATOM   2760  N  N   . ALA B 1 70  ? 17.832  -41.008 11.449  1.00 45.80  ? 70  ALA B N   1 
ATOM   2761  C  CA  . ALA B 1 70  ? 16.658  -40.252 11.043  1.00 45.79  ? 70  ALA B CA  1 
ATOM   2762  C  C   . ALA B 1 70  ? 16.795  -39.829 9.580   1.00 42.65  ? 70  ALA B C   1 
ATOM   2763  O  O   . ALA B 1 70  ? 15.799  -39.734 8.856   1.00 38.55  ? 70  ALA B O   1 
ATOM   2764  C  CB  . ALA B 1 70  ? 16.492  -39.060 11.929  1.00 49.10  ? 70  ALA B CB  1 
ATOM   2765  N  N   . TRP B 1 71  ? 18.023  -39.547 9.140   1.00 38.39  ? 71  TRP B N   1 
ATOM   2766  C  CA  . TRP B 1 71  ? 18.211  -39.124 7.766   1.00 40.58  ? 71  TRP B CA  1 
ATOM   2767  C  C   . TRP B 1 71  ? 17.606  -40.140 6.786   1.00 44.37  ? 71  TRP B C   1 
ATOM   2768  O  O   . TRP B 1 71  ? 16.923  -39.770 5.805   1.00 38.69  ? 71  TRP B O   1 
ATOM   2769  C  CB  . TRP B 1 71  ? 19.696  -38.914 7.459   1.00 41.46  ? 71  TRP B CB  1 
ATOM   2770  C  CG  . TRP B 1 71  ? 19.847  -38.359 6.082   1.00 45.20  ? 71  TRP B CG  1 
ATOM   2771  C  CD1 . TRP B 1 71  ? 19.784  -39.049 4.909   1.00 46.95  ? 71  TRP B CD1 1 
ATOM   2772  C  CD2 . TRP B 1 71  ? 19.931  -36.963 5.742   1.00 46.20  ? 71  TRP B CD2 1 
ATOM   2773  N  NE1 . TRP B 1 71  ? 19.893  -38.177 3.861   1.00 46.61  ? 71  TRP B NE1 1 
ATOM   2774  C  CE2 . TRP B 1 71  ? 19.971  -36.891 4.338   1.00 48.37  ? 71  TRP B CE2 1 
ATOM   2775  C  CE3 . TRP B 1 71  ? 19.996  -35.786 6.475   1.00 44.18  ? 71  TRP B CE3 1 
ATOM   2776  C  CZ2 . TRP B 1 71  ? 20.075  -35.679 3.666   1.00 49.11  ? 71  TRP B CZ2 1 
ATOM   2777  C  CZ3 . TRP B 1 71  ? 20.087  -34.593 5.801   1.00 48.54  ? 71  TRP B CZ3 1 
ATOM   2778  C  CH2 . TRP B 1 71  ? 20.098  -34.535 4.421   1.00 50.75  ? 71  TRP B CH2 1 
ATOM   2779  N  N   . ASP B 1 72  ? 17.862  -41.427 7.089   1.00 53.92  ? 72  ASP B N   1 
ATOM   2780  C  CA  . ASP B 1 72  ? 17.414  -42.565 6.299   1.00 58.22  ? 72  ASP B CA  1 
ATOM   2781  C  C   . ASP B 1 72  ? 15.896  -42.718 6.367   1.00 55.93  ? 72  ASP B C   1 
ATOM   2782  O  O   . ASP B 1 72  ? 15.279  -43.108 5.391   1.00 67.09  ? 72  ASP B O   1 
ATOM   2783  C  CB  . ASP B 1 72  ? 18.148  -43.833 6.703   1.00 56.64  ? 72  ASP B CB  1 
ATOM   2784  C  CG  . ASP B 1 72  ? 19.629  -43.846 6.323   1.00 66.96  ? 72  ASP B CG  1 
ATOM   2785  O  OD1 . ASP B 1 72  ? 20.018  -43.144 5.333   1.00 57.67  ? 72  ASP B OD1 1 
ATOM   2786  O  OD2 . ASP B 1 72  ? 20.409  -44.528 7.037   1.00 65.50  ? 72  ASP B OD2 1 
ATOM   2787  N  N   . ARG B 1 73  ? 15.272  -42.396 7.502   1.00 51.12  ? 73  ARG B N   1 
ATOM   2788  C  CA  . ARG B 1 73  ? 13.819  -42.460 7.598   1.00 48.86  ? 73  ARG B CA  1 
ATOM   2789  C  C   . ARG B 1 73  ? 13.144  -41.341 6.794   1.00 51.99  ? 73  ARG B C   1 
ATOM   2790  O  O   . ARG B 1 73  ? 12.013  -41.496 6.373   1.00 52.93  ? 73  ARG B O   1 
ATOM   2791  C  CB  . ARG B 1 73  ? 13.344  -42.435 9.054   1.00 43.09  ? 73  ARG B CB  1 
ATOM   2792  C  CG  . ARG B 1 73  ? 13.953  -43.553 9.885   1.00 41.66  ? 73  ARG B CG  1 
ATOM   2793  C  CD  . ARG B 1 73  ? 13.771  -43.384 11.354  1.00 45.25  ? 73  ARG B CD  1 
ATOM   2794  N  NE  . ARG B 1 73  ? 12.345  -43.241 11.676  1.00 45.54  ? 73  ARG B NE  1 
ATOM   2795  C  CZ  . ARG B 1 73  ? 11.930  -42.907 12.890  1.00 50.47  ? 73  ARG B CZ  1 
ATOM   2796  N  NH1 . ARG B 1 73  ? 12.837  -42.563 13.787  1.00 63.48  ? 73  ARG B NH1 1 
ATOM   2797  N  NH2 . ARG B 1 73  ? 10.634  -42.846 13.185  1.00 47.23  ? 73  ARG B NH2 1 
ATOM   2798  N  N   . LEU B 1 74  ? 13.802  -40.196 6.603   1.00 52.64  ? 74  LEU B N   1 
ATOM   2799  C  CA  . LEU B 1 74  ? 13.090  -39.003 6.172   1.00 47.14  ? 74  LEU B CA  1 
ATOM   2800  C  C   . LEU B 1 74  ? 13.242  -38.786 4.684   1.00 46.77  ? 74  LEU B C   1 
ATOM   2801  O  O   . LEU B 1 74  ? 12.405  -38.138 4.078   1.00 47.95  ? 74  LEU B O   1 
ATOM   2802  C  CB  . LEU B 1 74  ? 13.599  -37.767 6.907   1.00 47.91  ? 74  LEU B CB  1 
ATOM   2803  C  CG  . LEU B 1 74  ? 13.123  -37.660 8.354   1.00 52.53  ? 74  LEU B CG  1 
ATOM   2804  C  CD1 . LEU B 1 74  ? 13.848  -36.507 9.020   1.00 58.12  ? 74  LEU B CD1 1 
ATOM   2805  C  CD2 . LEU B 1 74  ? 11.600  -37.500 8.459   1.00 48.43  ? 74  LEU B CD2 1 
ATOM   2806  N  N   . PHE B 1 75  ? 14.377  -39.221 4.150   1.00 54.18  ? 75  PHE B N   1 
ATOM   2807  C  CA  . PHE B 1 75  ? 14.777  -38.872 2.802   1.00 59.64  ? 75  PHE B CA  1 
ATOM   2808  C  C   . PHE B 1 75  ? 15.235  -40.133 2.092   1.00 61.09  ? 75  PHE B C   1 
ATOM   2809  O  O   . PHE B 1 75  ? 15.672  -41.084 2.729   1.00 53.10  ? 75  PHE B O   1 
ATOM   2810  C  CB  . PHE B 1 75  ? 15.951  -37.894 2.815   1.00 54.52  ? 75  PHE B CB  1 
ATOM   2811  C  CG  . PHE B 1 75  ? 15.701  -36.665 3.668   1.00 54.68  ? 75  PHE B CG  1 
ATOM   2812  C  CD1 . PHE B 1 75  ? 14.626  -35.824 3.410   1.00 49.65  ? 75  PHE B CD1 1 
ATOM   2813  C  CD2 . PHE B 1 75  ? 16.516  -36.384 4.760   1.00 56.77  ? 75  PHE B CD2 1 
ATOM   2814  C  CE1 . PHE B 1 75  ? 14.390  -34.718 4.212   1.00 49.78  ? 75  PHE B CE1 1 
ATOM   2815  C  CE2 . PHE B 1 75  ? 16.269  -35.274 5.558   1.00 51.97  ? 75  PHE B CE2 1 
ATOM   2816  C  CZ  . PHE B 1 75  ? 15.208  -34.447 5.280   1.00 48.36  ? 75  PHE B CZ  1 
ATOM   2817  N  N   . SER B 1 76  ? 15.198  -40.108 0.764   1.00 68.78  ? 76  SER B N   1 
ATOM   2818  C  CA  . SER B 1 76  ? 15.965  -41.073 -0.005  1.00 71.73  ? 76  SER B CA  1 
ATOM   2819  C  C   . SER B 1 76  ? 17.009  -40.314 -0.820  1.00 67.24  ? 76  SER B C   1 
ATOM   2820  O  O   . SER B 1 76  ? 17.064  -39.086 -0.750  1.00 57.32  ? 76  SER B O   1 
ATOM   2821  C  CB  . SER B 1 76  ? 15.054  -41.951 -0.830  1.00 68.08  ? 76  SER B CB  1 
ATOM   2822  O  OG  . SER B 1 76  ? 13.980  -41.201 -1.385  1.00 64.97  ? 76  SER B OG  1 
ATOM   2823  N  N   . GLY B 1 77  ? 17.864  -41.039 -1.539  1.00 61.00  ? 77  GLY B N   1 
ATOM   2824  C  CA  . GLY B 1 77  ? 18.833  -40.364 -2.384  1.00 63.87  ? 77  GLY B CA  1 
ATOM   2825  C  C   . GLY B 1 77  ? 20.172  -40.288 -1.667  1.00 59.13  ? 77  GLY B C   1 
ATOM   2826  O  O   . GLY B 1 77  ? 20.485  -41.217 -0.927  1.00 62.85  ? 77  GLY B O   1 
ATOM   2827  N  N   . ALA B 1 78  ? 20.914  -39.197 -1.874  1.00 54.99  ? 78  ALA B N   1 
ATOM   2828  C  CA  . ALA B 1 78  ? 22.229  -39.069 -1.268  1.00 53.18  ? 78  ALA B CA  1 
ATOM   2829  C  C   . ALA B 1 78  ? 22.089  -38.830 0.241   1.00 50.58  ? 78  ALA B C   1 
ATOM   2830  O  O   . ALA B 1 78  ? 21.139  -38.214 0.689   1.00 49.96  ? 78  ALA B O   1 
ATOM   2831  C  CB  . ALA B 1 78  ? 23.041  -37.982 -1.956  1.00 48.93  ? 78  ALA B CB  1 
ATOM   2832  N  N   . ARG B 1 79  ? 23.049  -39.368 1.002   1.00 46.91  ? 79  ARG B N   1 
ATOM   2833  C  CA  . ARG B 1 79  ? 23.371  -38.962 2.355   1.00 42.51  ? 79  ARG B CA  1 
ATOM   2834  C  C   . ARG B 1 79  ? 24.575  -38.025 2.335   1.00 43.21  ? 79  ARG B C   1 
ATOM   2835  O  O   . ARG B 1 79  ? 25.465  -38.115 1.477   1.00 42.51  ? 79  ARG B O   1 
ATOM   2836  C  CB  . ARG B 1 79  ? 23.755  -40.164 3.205   1.00 38.68  ? 79  ARG B CB  1 
ATOM   2837  C  CG  . ARG B 1 79  ? 22.574  -41.104 3.321   1.00 37.90  ? 79  ARG B CG  1 
ATOM   2838  C  CD  . ARG B 1 79  ? 23.001  -42.389 3.982   1.00 44.98  ? 79  ARG B CD  1 
ATOM   2839  N  NE  . ARG B 1 79  ? 23.875  -42.095 5.119   1.00 49.31  ? 79  ARG B NE  1 
ATOM   2840  C  CZ  . ARG B 1 79  ? 23.437  -42.003 6.365   1.00 49.20  ? 79  ARG B CZ  1 
ATOM   2841  N  NH1 . ARG B 1 79  ? 22.187  -42.296 6.688   1.00 51.14  ? 79  ARG B NH1 1 
ATOM   2842  N  NH2 . ARG B 1 79  ? 24.273  -41.582 7.277   1.00 45.50  ? 79  ARG B NH2 1 
ATOM   2843  N  N   . PRO B 1 80  ? 24.654  -37.069 3.283   1.00 44.20  ? 80  PRO B N   1 
ATOM   2844  C  CA  . PRO B 1 80  ? 25.888  -36.301 3.454   1.00 43.81  ? 80  PRO B CA  1 
ATOM   2845  C  C   . PRO B 1 80  ? 27.003  -37.297 3.717   1.00 42.49  ? 80  PRO B C   1 
ATOM   2846  O  O   . PRO B 1 80  ? 26.818  -38.242 4.482   1.00 45.12  ? 80  PRO B O   1 
ATOM   2847  C  CB  . PRO B 1 80  ? 25.559  -35.408 4.641   1.00 50.67  ? 80  PRO B CB  1 
ATOM   2848  C  CG  . PRO B 1 80  ? 24.050  -35.289 4.578   1.00 53.96  ? 80  PRO B CG  1 
ATOM   2849  C  CD  . PRO B 1 80  ? 23.582  -36.681 4.210   1.00 46.99  ? 80  PRO B CD  1 
ATOM   2850  N  N   . ALA B 1 81  ? 28.152  -37.066 3.078   1.00 46.72  ? 81  ALA B N   1 
ATOM   2851  C  CA  . ALA B 1 81  ? 29.296  -37.971 3.151   1.00 42.03  ? 81  ALA B CA  1 
ATOM   2852  C  C   . ALA B 1 81  ? 29.729  -38.264 4.596   1.00 44.22  ? 81  ALA B C   1 
ATOM   2853  O  O   . ALA B 1 81  ? 30.137  -39.375 4.889   1.00 36.36  ? 81  ALA B O   1 
ATOM   2854  C  CB  . ALA B 1 81  ? 30.434  -37.378 2.350   1.00 36.36  ? 81  ALA B CB  1 
ATOM   2855  N  N   . GLY B 1 82  ? 29.623  -37.302 5.523   1.00 43.59  ? 82  GLY B N   1 
ATOM   2856  C  CA  . GLY B 1 82  ? 30.229  -37.454 6.838   1.00 40.61  ? 82  GLY B CA  1 
ATOM   2857  C  C   . GLY B 1 82  ? 29.258  -37.946 7.909   1.00 36.94  ? 82  GLY B C   1 
ATOM   2858  O  O   . GLY B 1 82  ? 29.648  -38.140 9.058   1.00 38.12  ? 82  GLY B O   1 
ATOM   2859  N  N   . LEU B 1 83  ? 27.999  -38.173 7.547   1.00 35.38  ? 83  LEU B N   1 
ATOM   2860  C  CA  . LEU B 1 83  ? 26.971  -38.373 8.554   1.00 39.12  ? 83  LEU B CA  1 
ATOM   2861  C  C   . LEU B 1 83  ? 26.964  -39.833 9.014   1.00 41.95  ? 83  LEU B C   1 
ATOM   2862  O  O   . LEU B 1 83  ? 26.803  -40.741 8.222   1.00 51.38  ? 83  LEU B O   1 
ATOM   2863  C  CB  . LEU B 1 83  ? 25.647  -37.925 7.937   1.00 43.17  ? 83  LEU B CB  1 
ATOM   2864  C  CG  . LEU B 1 83  ? 24.420  -38.092 8.826   1.00 46.35  ? 83  LEU B CG  1 
ATOM   2865  C  CD1 . LEU B 1 83  ? 24.609  -37.340 10.137  1.00 43.08  ? 83  LEU B CD1 1 
ATOM   2866  C  CD2 . LEU B 1 83  ? 23.143  -37.678 8.061   1.00 48.24  ? 83  LEU B CD2 1 
ATOM   2867  N  N   . HIS B 1 84  ? 27.210  -40.057 10.301  1.00 42.74  ? 84  HIS B N   1 
ATOM   2868  C  CA  . HIS B 1 84  ? 27.160  -41.361 10.962  1.00 38.93  ? 84  HIS B CA  1 
ATOM   2869  C  C   . HIS B 1 84  ? 26.747  -41.127 12.414  1.00 44.61  ? 84  HIS B C   1 
ATOM   2870  O  O   . HIS B 1 84  ? 26.672  -39.987 12.877  1.00 51.43  ? 84  HIS B O   1 
ATOM   2871  C  CB  . HIS B 1 84  ? 28.515  -42.062 10.943  1.00 34.18  ? 84  HIS B CB  1 
ATOM   2872  C  CG  . HIS B 1 84  ? 29.689  -41.189 11.216  1.00 35.72  ? 84  HIS B CG  1 
ATOM   2873  N  ND1 . HIS B 1 84  ? 30.454  -40.628 10.198  1.00 37.43  ? 84  HIS B ND1 1 
ATOM   2874  C  CD2 . HIS B 1 84  ? 30.229  -40.774 12.386  1.00 37.22  ? 84  HIS B CD2 1 
ATOM   2875  C  CE1 . HIS B 1 84  ? 31.465  -39.923 10.733  1.00 39.33  ? 84  HIS B CE1 1 
ATOM   2876  N  NE2 . HIS B 1 84  ? 31.367  -40.011 12.060  1.00 36.21  ? 84  HIS B NE2 1 
ATOM   2877  N  N   . PRO B 1 85  ? 26.384  -42.163 13.184  1.00 39.34  ? 85  PRO B N   1 
ATOM   2878  C  CA  . PRO B 1 85  ? 26.083  -41.984 14.604  1.00 34.27  ? 85  PRO B CA  1 
ATOM   2879  C  C   . PRO B 1 85  ? 27.350  -41.581 15.333  1.00 37.36  ? 85  PRO B C   1 
ATOM   2880  O  O   . PRO B 1 85  ? 28.443  -41.907 14.900  1.00 48.01  ? 85  PRO B O   1 
ATOM   2881  C  CB  . PRO B 1 85  ? 25.567  -43.327 15.049  1.00 33.29  ? 85  PRO B CB  1 
ATOM   2882  C  CG  . PRO B 1 85  ? 25.018  -43.878 13.778  1.00 35.57  ? 85  PRO B CG  1 
ATOM   2883  C  CD  . PRO B 1 85  ? 26.098  -43.520 12.733  1.00 39.09  ? 85  PRO B CD  1 
ATOM   2884  N  N   . PHE B 1 86  ? 27.158  -40.834 16.411  1.00 35.67  ? 86  PHE B N   1 
ATOM   2885  C  CA  . PHE B 1 86  ? 28.234  -40.447 17.294  1.00 36.12  ? 86  PHE B CA  1 
ATOM   2886  C  C   . PHE B 1 86  ? 28.925  -41.735 17.721  1.00 38.34  ? 86  PHE B C   1 
ATOM   2887  O  O   . PHE B 1 86  ? 28.214  -42.682 18.052  1.00 35.45  ? 86  PHE B O   1 
ATOM   2888  C  CB  . PHE B 1 86  ? 27.587  -39.695 18.470  1.00 34.89  ? 86  PHE B CB  1 
ATOM   2889  C  CG  . PHE B 1 86  ? 28.583  -39.213 19.504  1.00 36.69  ? 86  PHE B CG  1 
ATOM   2890  C  CD1 . PHE B 1 86  ? 29.239  -38.005 19.332  1.00 41.41  ? 86  PHE B CD1 1 
ATOM   2891  C  CD2 . PHE B 1 86  ? 28.899  -39.968 20.614  1.00 38.87  ? 86  PHE B CD2 1 
ATOM   2892  C  CE1 . PHE B 1 86  ? 30.171  -37.557 20.255  1.00 39.63  ? 86  PHE B CE1 1 
ATOM   2893  C  CE2 . PHE B 1 86  ? 29.815  -39.504 21.550  1.00 39.46  ? 86  PHE B CE2 1 
ATOM   2894  C  CZ  . PHE B 1 86  ? 30.465  -38.312 21.357  1.00 40.48  ? 86  PHE B CZ  1 
ATOM   2895  N  N   . ARG B 1 87  ? 30.265  -41.750 17.714  1.00 41.49  ? 87  ARG B N   1 
ATOM   2896  C  CA  . ARG B 1 87  ? 31.037  -42.921 18.124  1.00 43.31  ? 87  ARG B CA  1 
ATOM   2897  C  C   . ARG B 1 87  ? 31.416  -42.760 19.597  1.00 43.37  ? 87  ARG B C   1 
ATOM   2898  O  O   . ARG B 1 87  ? 32.172  -41.811 19.912  1.00 40.49  ? 87  ARG B O   1 
ATOM   2899  C  CB  . ARG B 1 87  ? 32.353  -43.113 17.353  1.00 45.31  ? 87  ARG B CB  1 
ATOM   2900  C  CG  . ARG B 1 87  ? 32.429  -42.688 15.890  1.00 43.26  ? 87  ARG B CG  1 
ATOM   2901  C  CD  . ARG B 1 87  ? 33.899  -42.774 15.329  1.00 39.05  ? 87  ARG B CD  1 
ATOM   2902  N  N   . GLU B 1 88  ? 30.892  -43.674 20.457  1.00 42.71  ? 88  GLU B N   1 
ATOM   2903  C  CA  . GLU B 1 88  ? 31.295  -43.810 21.856  1.00 40.86  ? 88  GLU B CA  1 
ATOM   2904  C  C   . GLU B 1 88  ? 32.822  -43.842 21.912  1.00 42.59  ? 88  GLU B C   1 
ATOM   2905  O  O   . GLU B 1 88  ? 33.473  -44.311 20.981  1.00 39.18  ? 88  GLU B O   1 
ATOM   2906  C  CB  . GLU B 1 88  ? 30.917  -45.097 22.589  1.00 41.35  ? 88  GLU B CB  1 
ATOM   2907  C  CG  . GLU B 1 88  ? 29.446  -45.199 22.931  1.00 50.89  ? 88  GLU B CG  1 
ATOM   2908  C  CD  . GLU B 1 88  ? 29.178  -45.824 24.291  1.00 58.61  ? 88  GLU B CD  1 
ATOM   2909  O  OE1 . GLU B 1 88  ? 29.829  -46.853 24.579  1.00 61.03  ? 88  GLU B OE1 1 
ATOM   2910  O  OE2 . GLU B 1 88  ? 28.277  -45.341 25.046  1.00 47.29  ? 88  GLU B OE2 1 
ATOM   2911  N  N   . LEU B 1 89  ? 33.407  -43.283 22.976  1.00 43.34  ? 89  LEU B N   1 
ATOM   2912  C  CA  . LEU B 1 89  ? 34.825  -43.435 23.257  1.00 39.78  ? 89  LEU B CA  1 
ATOM   2913  C  C   . LEU B 1 89  ? 34.938  -43.986 24.677  1.00 46.09  ? 89  LEU B C   1 
ATOM   2914  O  O   . LEU B 1 89  ? 34.552  -43.324 25.636  1.00 38.17  ? 89  LEU B O   1 
ATOM   2915  C  CB  . LEU B 1 89  ? 35.629  -42.150 23.116  1.00 40.56  ? 89  LEU B CB  1 
ATOM   2916  C  CG  . LEU B 1 89  ? 35.548  -41.422 21.766  1.00 44.90  ? 89  LEU B CG  1 
ATOM   2917  C  CD1 . LEU B 1 89  ? 36.324  -40.125 21.789  1.00 43.17  ? 89  LEU B CD1 1 
ATOM   2918  C  CD2 . LEU B 1 89  ? 36.053  -42.281 20.631  1.00 47.81  ? 89  LEU B CD2 1 
ATOM   2919  N  N   . ASP B 1 90  ? 35.456  -45.225 24.787  1.00 54.57  ? 90  ASP B N   1 
ATOM   2920  C  CA  . ASP B 1 90  ? 35.744  -45.872 26.052  1.00 52.98  ? 90  ASP B CA  1 
ATOM   2921  C  C   . ASP B 1 90  ? 37.240  -45.690 26.318  1.00 46.69  ? 90  ASP B C   1 
ATOM   2922  O  O   . ASP B 1 90  ? 38.080  -46.418 25.824  1.00 48.28  ? 90  ASP B O   1 
ATOM   2923  C  CB  . ASP B 1 90  ? 35.181  -47.283 26.071  1.00 52.98  ? 90  ASP B CB  1 
ATOM   2924  C  CG  . ASP B 1 90  ? 34.952  -47.823 27.474  1.00 65.29  ? 90  ASP B CG  1 
ATOM   2925  O  OD1 . ASP B 1 90  ? 34.167  -47.223 28.224  1.00 78.50  ? 90  ASP B OD1 1 
ATOM   2926  O  OD2 . ASP B 1 90  ? 35.622  -48.791 27.850  1.00 72.51  ? 90  ASP B OD2 1 
ATOM   2927  N  N   . GLY B 1 91  ? 37.559  -44.641 27.067  1.00 42.20  ? 91  GLY B N   1 
ATOM   2928  C  CA  . GLY B 1 91  ? 38.937  -44.334 27.376  1.00 39.76  ? 91  GLY B CA  1 
ATOM   2929  C  C   . GLY B 1 91  ? 39.338  -45.121 28.618  1.00 39.40  ? 91  GLY B C   1 
ATOM   2930  O  O   . GLY B 1 91  ? 38.481  -45.681 29.303  1.00 38.40  ? 91  GLY B O   1 
ATOM   2931  N  N   . PRO B 1 92  ? 40.639  -45.108 28.984  1.00 38.18  ? 92  PRO B N   1 
ATOM   2932  C  CA  . PRO B 1 92  ? 41.106  -45.860 30.146  1.00 34.16  ? 92  PRO B CA  1 
ATOM   2933  C  C   . PRO B 1 92  ? 40.364  -45.377 31.384  1.00 37.29  ? 92  PRO B C   1 
ATOM   2934  O  O   . PRO B 1 92  ? 39.998  -46.167 32.221  1.00 40.19  ? 92  PRO B O   1 
ATOM   2935  C  CB  . PRO B 1 92  ? 42.617  -45.591 30.258  1.00 34.11  ? 92  PRO B CB  1 
ATOM   2936  C  CG  . PRO B 1 92  ? 42.963  -44.630 29.125  1.00 38.49  ? 92  PRO B CG  1 
ATOM   2937  C  CD  . PRO B 1 92  ? 41.677  -44.240 28.392  1.00 41.05  ? 92  PRO B CD  1 
ATOM   2938  N  N   . VAL B 1 93  ? 40.149  -44.059 31.475  1.00 40.01  ? 93  VAL B N   1 
ATOM   2939  C  CA  . VAL B 1 93  ? 39.556  -43.432 32.638  1.00 39.40  ? 93  VAL B CA  1 
ATOM   2940  C  C   . VAL B 1 93  ? 38.194  -42.840 32.304  1.00 37.18  ? 93  VAL B C   1 
ATOM   2941  O  O   . VAL B 1 93  ? 37.265  -43.023 33.068  1.00 37.13  ? 93  VAL B O   1 
ATOM   2942  C  CB  . VAL B 1 93  ? 40.506  -42.340 33.144  1.00 41.29  ? 93  VAL B CB  1 
ATOM   2943  C  CG1 . VAL B 1 93  ? 39.847  -41.529 34.258  1.00 36.49  ? 93  VAL B CG1 1 
ATOM   2944  C  CG2 . VAL B 1 93  ? 41.840  -42.933 33.597  1.00 40.10  ? 93  VAL B CG2 1 
ATOM   2945  N  N   . HIS B 1 94  ? 38.095  -42.088 31.199  1.00 40.18  ? 94  HIS B N   1 
ATOM   2946  C  CA  . HIS B 1 94  ? 36.880  -41.329 30.917  1.00 37.63  ? 94  HIS B CA  1 
ATOM   2947  C  C   . HIS B 1 94  ? 36.204  -41.880 29.658  1.00 36.38  ? 94  HIS B C   1 
ATOM   2948  O  O   . HIS B 1 94  ? 36.886  -42.318 28.722  1.00 37.57  ? 94  HIS B O   1 
ATOM   2949  C  CB  . HIS B 1 94  ? 37.185  -39.833 30.756  1.00 37.10  ? 94  HIS B CB  1 
ATOM   2950  C  CG  . HIS B 1 94  ? 37.825  -39.171 31.913  1.00 36.78  ? 94  HIS B CG  1 
ATOM   2951  N  ND1 . HIS B 1 94  ? 37.154  -38.998 33.100  1.00 36.77  ? 94  HIS B ND1 1 
ATOM   2952  C  CD2 . HIS B 1 94  ? 39.079  -38.680 32.114  1.00 40.43  ? 94  HIS B CD2 1 
ATOM   2953  C  CE1 . HIS B 1 94  ? 37.969  -38.384 33.974  1.00 33.83  ? 94  HIS B CE1 1 
ATOM   2954  N  NE2 . HIS B 1 94  ? 39.140  -38.190 33.406  1.00 33.11  ? 94  HIS B NE2 1 
ATOM   2955  N  N   . ARG B 1 95  ? 34.866  -41.762 29.628  1.00 35.90  ? 95  ARG B N   1 
ATOM   2956  C  CA  . ARG B 1 95  ? 34.023  -42.304 28.569  1.00 41.17  ? 95  ARG B CA  1 
ATOM   2957  C  C   . ARG B 1 95  ? 33.156  -41.205 27.935  1.00 38.13  ? 95  ARG B C   1 
ATOM   2958  O  O   . ARG B 1 95  ? 32.518  -40.422 28.620  1.00 38.49  ? 95  ARG B O   1 
ATOM   2959  C  CB  . ARG B 1 95  ? 33.226  -43.351 29.355  1.00 43.59  ? 95  ARG B CB  1 
ATOM   2960  C  CG  . ARG B 1 95  ? 32.133  -44.176 28.711  1.00 48.53  ? 95  ARG B CG  1 
ATOM   2961  C  CD  . ARG B 1 95  ? 31.735  -45.212 29.752  1.00 53.20  ? 95  ARG B CD  1 
ATOM   2962  N  NE  . ARG B 1 95  ? 30.513  -45.842 29.250  1.00 62.26  ? 95  ARG B NE  1 
ATOM   2963  N  N   . ALA B 1 96  ? 33.152  -41.121 26.615  1.00 35.12  ? 96  ALA B N   1 
ATOM   2964  C  CA  . ALA B 1 96  ? 32.239  -40.247 25.898  1.00 40.91  ? 96  ALA B CA  1 
ATOM   2965  C  C   . ALA B 1 96  ? 31.041  -41.084 25.443  1.00 44.49  ? 96  ALA B C   1 
ATOM   2966  O  O   . ALA B 1 96  ? 31.166  -41.950 24.585  1.00 43.56  ? 96  ALA B O   1 
ATOM   2967  C  CB  . ALA B 1 96  ? 32.959  -39.600 24.723  1.00 41.60  ? 96  ALA B CB  1 
ATOM   2968  N  N   . VAL B 1 97  ? 29.876  -40.869 26.042  1.00 46.21  ? 97  VAL B N   1 
ATOM   2969  C  CA  . VAL B 1 97  ? 28.744  -41.729 25.727  1.00 44.78  ? 97  VAL B CA  1 
ATOM   2970  C  C   . VAL B 1 97  ? 28.052  -41.220 24.475  1.00 38.95  ? 97  VAL B C   1 
ATOM   2971  O  O   . VAL B 1 97  ? 28.230  -40.042 24.134  1.00 36.93  ? 97  VAL B O   1 
ATOM   2972  C  CB  . VAL B 1 97  ? 27.726  -41.838 26.873  1.00 41.26  ? 97  VAL B CB  1 
ATOM   2973  C  CG1 . VAL B 1 97  ? 28.405  -42.417 28.107  1.00 39.67  ? 97  VAL B CG1 1 
ATOM   2974  C  CG2 . VAL B 1 97  ? 27.069  -40.497 27.167  1.00 42.43  ? 97  VAL B CG2 1 
ATOM   2975  N  N   . ALA B 1 98  ? 27.275  -42.136 23.872  1.00 33.37  ? 98  ALA B N   1 
ATOM   2976  C  CA  . ALA B 1 98  ? 26.375  -41.851 22.771  1.00 36.32  ? 98  ALA B CA  1 
ATOM   2977  C  C   . ALA B 1 98  ? 24.927  -42.014 23.211  1.00 36.59  ? 98  ALA B C   1 
ATOM   2978  O  O   . ALA B 1 98  ? 24.579  -43.030 23.741  1.00 39.62  ? 98  ALA B O   1 
ATOM   2979  C  CB  . ALA B 1 98  ? 26.673  -42.764 21.614  1.00 37.73  ? 98  ALA B CB  1 
ATOM   2980  N  N   . THR B 1 99  ? 24.077  -41.015 23.001  1.00 42.36  ? 99  THR B N   1 
ATOM   2981  C  CA  . THR B 1 99  ? 22.697  -41.082 23.444  1.00 35.36  ? 99  THR B CA  1 
ATOM   2982  C  C   . THR B 1 99  ? 21.794  -40.772 22.257  1.00 33.41  ? 99  THR B C   1 
ATOM   2983  O  O   . THR B 1 99  ? 22.235  -40.214 21.273  1.00 26.53  ? 99  THR B O   1 
ATOM   2984  C  CB  . THR B 1 99  ? 22.489  -40.108 24.604  1.00 32.33  ? 99  THR B CB  1 
ATOM   2985  O  OG1 . THR B 1 99  ? 22.816  -38.794 24.165  1.00 30.72  ? 99  THR B OG1 1 
ATOM   2986  C  CG2 . THR B 1 99  ? 23.372  -40.466 25.780  1.00 32.42  ? 99  THR B CG2 1 
ATOM   2987  N  N   . PRO B 1 100 ? 20.515  -41.177 22.312  1.00 37.58  ? 100 PRO B N   1 
ATOM   2988  C  CA  . PRO B 1 100 ? 19.602  -41.065 21.179  1.00 36.43  ? 100 PRO B CA  1 
ATOM   2989  C  C   . PRO B 1 100 ? 19.247  -39.638 20.821  1.00 33.47  ? 100 PRO B C   1 
ATOM   2990  O  O   . PRO B 1 100 ? 19.024  -38.832 21.717  1.00 36.89  ? 100 PRO B O   1 
ATOM   2991  C  CB  . PRO B 1 100 ? 18.321  -41.783 21.658  1.00 35.47  ? 100 PRO B CB  1 
ATOM   2992  C  CG  . PRO B 1 100 ? 18.693  -42.520 22.892  1.00 34.50  ? 100 PRO B CG  1 
ATOM   2993  C  CD  . PRO B 1 100 ? 19.882  -41.800 23.481  1.00 39.37  ? 100 PRO B CD  1 
ATOM   2994  N  N   . GLY B 1 101 ? 19.112  -39.378 19.526  1.00 31.55  ? 101 GLY B N   1 
ATOM   2995  C  CA  . GLY B 1 101 ? 18.675  -38.069 19.074  1.00 33.09  ? 101 GLY B CA  1 
ATOM   2996  C  C   . GLY B 1 101 ? 18.523  -38.032 17.561  1.00 33.87  ? 101 GLY B C   1 
ATOM   2997  O  O   . GLY B 1 101 ? 19.487  -38.217 16.848  1.00 30.95  ? 101 GLY B O   1 
ATOM   2998  N  N   . ASP B 1 102 ? 17.311  -37.771 17.074  1.00 32.27  ? 102 ASP B N   1 
ATOM   2999  C  CA  . ASP B 1 102 ? 17.074  -37.703 15.645  1.00 31.66  ? 102 ASP B CA  1 
ATOM   3000  C  C   . ASP B 1 102 ? 17.092  -36.265 15.125  1.00 30.40  ? 102 ASP B C   1 
ATOM   3001  O  O   . ASP B 1 102 ? 17.544  -36.016 14.023  1.00 32.47  ? 102 ASP B O   1 
ATOM   3002  C  CB  . ASP B 1 102 ? 15.757  -38.371 15.325  1.00 37.19  ? 102 ASP B CB  1 
ATOM   3003  C  CG  . ASP B 1 102 ? 15.721  -39.862 15.639  1.00 39.86  ? 102 ASP B CG  1 
ATOM   3004  O  OD1 . ASP B 1 102 ? 16.767  -40.495 15.421  1.00 34.38  ? 102 ASP B OD1 1 
ATOM   3005  O  OD2 . ASP B 1 102 ? 14.658  -40.361 16.069  1.00 42.44  ? 102 ASP B OD2 1 
ATOM   3006  N  N   . LEU B 1 103 ? 16.573  -35.319 15.907  1.00 30.28  ? 103 LEU B N   1 
ATOM   3007  C  CA  . LEU B 1 103 ? 16.544  -33.914 15.531  1.00 27.44  ? 103 LEU B CA  1 
ATOM   3008  C  C   . LEU B 1 103 ? 17.182  -33.095 16.635  1.00 23.70  ? 103 LEU B C   1 
ATOM   3009  O  O   . LEU B 1 103 ? 17.010  -33.412 17.801  1.00 21.99  ? 103 LEU B O   1 
ATOM   3010  C  CB  . LEU B 1 103 ? 15.120  -33.405 15.341  1.00 30.06  ? 103 LEU B CB  1 
ATOM   3011  C  CG  . LEU B 1 103 ? 14.332  -34.069 14.219  1.00 35.26  ? 103 LEU B CG  1 
ATOM   3012  C  CD1 . LEU B 1 103 ? 12.891  -33.675 14.222  1.00 37.49  ? 103 LEU B CD1 1 
ATOM   3013  C  CD2 . LEU B 1 103 ? 14.990  -33.707 12.911  1.00 42.85  ? 103 LEU B CD2 1 
ATOM   3014  N  N   . LEU B 1 104 ? 17.864  -32.038 16.207  1.00 24.32  ? 104 LEU B N   1 
ATOM   3015  C  CA  . LEU B 1 104 ? 18.418  -31.014 17.067  1.00 26.28  ? 104 LEU B CA  1 
ATOM   3016  C  C   . LEU B 1 104 ? 17.813  -29.665 16.667  1.00 24.44  ? 104 LEU B C   1 
ATOM   3017  O  O   . LEU B 1 104 ? 17.831  -29.304 15.494  1.00 28.69  ? 104 LEU B O   1 
ATOM   3018  C  CB  . LEU B 1 104 ? 19.939  -30.989 16.919  1.00 28.58  ? 104 LEU B CB  1 
ATOM   3019  C  CG  . LEU B 1 104 ? 20.621  -29.761 17.542  1.00 31.20  ? 104 LEU B CG  1 
ATOM   3020  C  CD1 . LEU B 1 104 ? 20.634  -29.821 19.071  1.00 32.05  ? 104 LEU B CD1 1 
ATOM   3021  C  CD2 . LEU B 1 104 ? 22.013  -29.612 16.966  1.00 34.24  ? 104 LEU B CD2 1 
ATOM   3022  N  N   . PHE B 1 105 ? 17.333  -28.893 17.646  1.00 22.78  ? 105 PHE B N   1 
ATOM   3023  C  CA  . PHE B 1 105 ? 17.050  -27.484 17.427  1.00 23.12  ? 105 PHE B CA  1 
ATOM   3024  C  C   . PHE B 1 105 ? 17.970  -26.689 18.330  1.00 22.50  ? 105 PHE B C   1 
ATOM   3025  O  O   . PHE B 1 105 ? 17.898  -26.832 19.543  1.00 22.50  ? 105 PHE B O   1 
ATOM   3026  C  CB  . PHE B 1 105 ? 15.595  -27.112 17.693  1.00 24.89  ? 105 PHE B CB  1 
ATOM   3027  C  CG  . PHE B 1 105 ? 14.639  -27.931 16.843  1.00 27.04  ? 105 PHE B CG  1 
ATOM   3028  C  CD1 . PHE B 1 105 ? 14.395  -27.578 15.522  1.00 28.83  ? 105 PHE B CD1 1 
ATOM   3029  C  CD2 . PHE B 1 105 ? 14.026  -29.067 17.355  1.00 27.16  ? 105 PHE B CD2 1 
ATOM   3030  C  CE1 . PHE B 1 105 ? 13.544  -28.334 14.740  1.00 29.39  ? 105 PHE B CE1 1 
ATOM   3031  C  CE2 . PHE B 1 105 ? 13.184  -29.835 16.570  1.00 27.08  ? 105 PHE B CE2 1 
ATOM   3032  C  CZ  . PHE B 1 105 ? 12.937  -29.465 15.272  1.00 25.34  ? 105 PHE B CZ  1 
ATOM   3033  N  N   . HIS B 1 106 ? 18.864  -25.918 17.695  1.00 23.35  ? 106 HIS B N   1 
ATOM   3034  C  CA  . HIS B 1 106 ? 19.781  -25.054 18.398  1.00 23.41  ? 106 HIS B CA  1 
ATOM   3035  C  C   . HIS B 1 106 ? 19.266  -23.639 18.232  1.00 22.55  ? 106 HIS B C   1 
ATOM   3036  O  O   . HIS B 1 106 ? 19.481  -23.022 17.192  1.00 25.13  ? 106 HIS B O   1 
ATOM   3037  C  CB  . HIS B 1 106 ? 21.193  -25.250 17.853  1.00 24.04  ? 106 HIS B CB  1 
ATOM   3038  C  CG  . HIS B 1 106 ? 22.225  -24.391 18.521  1.00 25.43  ? 106 HIS B CG  1 
ATOM   3039  N  ND1 . HIS B 1 106 ? 23.402  -24.038 17.911  1.00 23.01  ? 106 HIS B ND1 1 
ATOM   3040  C  CD2 . HIS B 1 106 ? 22.227  -23.790 19.748  1.00 28.38  ? 106 HIS B CD2 1 
ATOM   3041  C  CE1 . HIS B 1 106 ? 24.094  -23.277 18.748  1.00 25.01  ? 106 HIS B CE1 1 
ATOM   3042  N  NE2 . HIS B 1 106 ? 23.408  -23.102 19.872  1.00 26.30  ? 106 HIS B NE2 1 
ATOM   3043  N  N   . ILE B 1 107 ? 18.574  -23.177 19.277  1.00 24.25  ? 107 ILE B N   1 
ATOM   3044  C  CA  . ILE B 1 107 ? 17.828  -21.938 19.234  1.00 25.59  ? 107 ILE B CA  1 
ATOM   3045  C  C   . ILE B 1 107 ? 18.592  -20.925 20.061  1.00 29.36  ? 107 ILE B C   1 
ATOM   3046  O  O   . ILE B 1 107 ? 18.905  -21.225 21.214  1.00 32.63  ? 107 ILE B O   1 
ATOM   3047  C  CB  . ILE B 1 107 ? 16.404  -22.134 19.773  1.00 26.33  ? 107 ILE B CB  1 
ATOM   3048  C  CG1 . ILE B 1 107 ? 15.681  -23.249 18.988  1.00 25.35  ? 107 ILE B CG1 1 
ATOM   3049  C  CG2 . ILE B 1 107 ? 15.640  -20.808 19.769  1.00 25.60  ? 107 ILE B CG2 1 
ATOM   3050  C  CD1 . ILE B 1 107 ? 14.380  -23.692 19.615  1.00 27.41  ? 107 ILE B CD1 1 
ATOM   3051  N  N   . ARG B 1 108 ? 18.867  -19.745 19.473  1.00 27.69  ? 108 ARG B N   1 
ATOM   3052  C  CA  . ARG B 1 108 ? 19.703  -18.745 20.117  1.00 26.33  ? 108 ARG B CA  1 
ATOM   3053  C  C   . ARG B 1 108 ? 19.055  -17.381 19.982  1.00 25.64  ? 108 ARG B C   1 
ATOM   3054  O  O   . ARG B 1 108 ? 18.506  -17.085 18.940  1.00 28.98  ? 108 ARG B O   1 
ATOM   3055  C  CB  . ARG B 1 108 ? 21.100  -18.663 19.493  1.00 26.97  ? 108 ARG B CB  1 
ATOM   3056  C  CG  . ARG B 1 108 ? 21.994  -19.815 19.908  1.00 32.01  ? 108 ARG B CG  1 
ATOM   3057  C  CD  . ARG B 1 108 ? 23.269  -19.815 19.134  1.00 33.01  ? 108 ARG B CD  1 
ATOM   3058  N  NE  . ARG B 1 108 ? 23.079  -20.176 17.722  1.00 37.64  ? 108 ARG B NE  1 
ATOM   3059  C  CZ  . ARG B 1 108 ? 24.131  -20.380 16.935  1.00 37.30  ? 108 ARG B CZ  1 
ATOM   3060  N  NH1 . ARG B 1 108 ? 25.356  -20.284 17.423  1.00 33.19  ? 108 ARG B NH1 1 
ATOM   3061  N  NH2 . ARG B 1 108 ? 23.966  -20.716 15.683  1.00 44.15  ? 108 ARG B NH2 1 
ATOM   3062  N  N   . ALA B 1 109 ? 19.201  -16.551 21.009  1.00 26.81  ? 109 ALA B N   1 
ATOM   3063  C  CA  . ALA B 1 109 ? 18.807  -15.163 20.936  1.00 26.28  ? 109 ALA B CA  1 
ATOM   3064  C  C   . ALA B 1 109 ? 19.496  -14.359 22.032  1.00 28.71  ? 109 ALA B C   1 
ATOM   3065  O  O   . ALA B 1 109 ? 20.202  -14.903 22.889  1.00 27.56  ? 109 ALA B O   1 
ATOM   3066  C  CB  . ALA B 1 109 ? 17.334  -15.085 21.080  1.00 26.04  ? 109 ALA B CB  1 
ATOM   3067  N  N   . SER B 1 110 ? 19.217  -13.056 22.043  1.00 29.86  ? 110 SER B N   1 
ATOM   3068  C  CA  . SER B 1 110 ? 19.713  -12.212 23.112  1.00 31.30  ? 110 SER B CA  1 
ATOM   3069  C  C   . SER B 1 110 ? 18.894  -12.378 24.395  1.00 34.06  ? 110 SER B C   1 
ATOM   3070  O  O   . SER B 1 110 ? 19.365  -11.975 25.448  1.00 33.21  ? 110 SER B O   1 
ATOM   3071  C  CB  . SER B 1 110 ? 19.705  -10.800 22.666  1.00 36.35  ? 110 SER B CB  1 
ATOM   3072  O  OG  . SER B 1 110 ? 18.371  -10.329 22.495  1.00 39.50  ? 110 SER B OG  1 
ATOM   3073  N  N   . ARG B 1 111 ? 17.683  -12.975 24.343  1.00 36.13  ? 111 ARG B N   1 
ATOM   3074  C  CA  . ARG B 1 111 ? 16.851  -13.127 25.531  1.00 31.49  ? 111 ARG B CA  1 
ATOM   3075  C  C   . ARG B 1 111 ? 16.169  -14.488 25.494  1.00 28.71  ? 111 ARG B C   1 
ATOM   3076  O  O   . ARG B 1 111 ? 15.735  -14.937 24.449  1.00 25.97  ? 111 ARG B O   1 
ATOM   3077  C  CB  . ARG B 1 111 ? 15.684  -12.136 25.536  1.00 37.41  ? 111 ARG B CB  1 
ATOM   3078  C  CG  . ARG B 1 111 ? 15.952  -10.668 25.239  1.00 46.31  ? 111 ARG B CG  1 
ATOM   3079  C  CD  . ARG B 1 111 ? 14.678  -9.962  24.707  1.00 51.97  ? 111 ARG B CD  1 
ATOM   3080  N  NE  . ARG B 1 111 ? 13.503  -10.077 25.595  1.00 48.91  ? 111 ARG B NE  1 
ATOM   3081  C  CZ  . ARG B 1 111 ? 13.315  -9.486  26.781  1.00 47.03  ? 111 ARG B CZ  1 
ATOM   3082  N  NH1 . ARG B 1 111 ? 14.089  -8.496  27.175  1.00 49.31  ? 111 ARG B NH1 1 
ATOM   3083  N  NH2 . ARG B 1 111 ? 12.303  -9.805  27.564  1.00 51.55  ? 111 ARG B NH2 1 
ATOM   3084  N  N   . LEU B 1 112 ? 16.037  -15.115 26.653  1.00 28.28  ? 112 LEU B N   1 
ATOM   3085  C  CA  . LEU B 1 112 ? 15.495  -16.461 26.743  1.00 29.37  ? 112 LEU B CA  1 
ATOM   3086  C  C   . LEU B 1 112 ? 14.061  -16.580 26.217  1.00 29.32  ? 112 LEU B C   1 
ATOM   3087  O  O   . LEU B 1 112 ? 13.689  -17.585 25.625  1.00 31.33  ? 112 LEU B O   1 
ATOM   3088  C  CB  . LEU B 1 112 ? 15.591  -16.886 28.203  1.00 30.05  ? 112 LEU B CB  1 
ATOM   3089  C  CG  . LEU B 1 112 ? 15.416  -18.377 28.441  1.00 36.67  ? 112 LEU B CG  1 
ATOM   3090  C  CD1 . LEU B 1 112 ? 16.299  -19.237 27.513  1.00 38.06  ? 112 LEU B CD1 1 
ATOM   3091  C  CD2 . LEU B 1 112 ? 15.795  -18.652 29.882  1.00 45.00  ? 112 LEU B CD2 1 
ATOM   3092  N  N   . ASP B 1 113 ? 13.243  -15.542 26.390  1.00 28.44  ? 113 ASP B N   1 
ATOM   3093  C  CA  . ASP B 1 113 ? 11.826  -15.644 26.077  1.00 27.90  ? 113 ASP B CA  1 
ATOM   3094  C  C   . ASP B 1 113 ? 11.622  -15.831 24.593  1.00 25.94  ? 113 ASP B C   1 
ATOM   3095  O  O   . ASP B 1 113 ? 10.692  -16.493 24.214  1.00 26.04  ? 113 ASP B O   1 
ATOM   3096  C  CB  . ASP B 1 113 ? 11.031  -14.415 26.493  1.00 32.20  ? 113 ASP B CB  1 
ATOM   3097  C  CG  . ASP B 1 113 ? 11.568  -13.093 25.962  1.00 33.27  ? 113 ASP B CG  1 
ATOM   3098  O  OD1 . ASP B 1 113 ? 12.639  -12.704 26.487  1.00 32.73  ? 113 ASP B OD1 1 
ATOM   3099  O  OD2 . ASP B 1 113 ? 10.921  -12.500 25.034  1.00 37.15  ? 113 ASP B OD2 1 
ATOM   3100  N  N   . LEU B 1 114 ? 12.462  -15.212 23.763  1.00 28.49  ? 114 LEU B N   1 
ATOM   3101  C  CA  . LEU B 1 114 ? 12.390  -15.405 22.321  1.00 28.44  ? 114 LEU B CA  1 
ATOM   3102  C  C   . LEU B 1 114 ? 12.692  -16.846 21.940  1.00 25.27  ? 114 LEU B C   1 
ATOM   3103  O  O   . LEU B 1 114 ? 12.037  -17.389 21.039  1.00 21.45  ? 114 LEU B O   1 
ATOM   3104  C  CB  . LEU B 1 114 ? 13.381  -14.491 21.612  1.00 29.96  ? 114 LEU B CB  1 
ATOM   3105  C  CG  . LEU B 1 114 ? 13.006  -13.015 21.591  1.00 35.31  ? 114 LEU B CG  1 
ATOM   3106  C  CD1 . LEU B 1 114 ? 14.150  -12.214 20.997  1.00 43.12  ? 114 LEU B CD1 1 
ATOM   3107  C  CD2 . LEU B 1 114 ? 11.751  -12.815 20.759  1.00 32.83  ? 114 LEU B CD2 1 
ATOM   3108  N  N   . CYS B 1 115 ? 13.727  -17.415 22.579  1.00 24.89  ? 115 CYS B N   1 
ATOM   3109  C  CA  . CYS B 1 115 ? 14.050  -18.819 22.401  1.00 23.44  ? 115 CYS B CA  1 
ATOM   3110  C  C   . CYS B 1 115 ? 12.842  -19.669 22.757  1.00 25.11  ? 115 CYS B C   1 
ATOM   3111  O  O   . CYS B 1 115 ? 12.492  -20.595 22.034  1.00 24.68  ? 115 CYS B O   1 
ATOM   3112  C  CB  . CYS B 1 115 ? 15.204  -19.232 23.277  1.00 24.74  ? 115 CYS B CB  1 
ATOM   3113  S  SG  . CYS B 1 115 ? 16.726  -18.398 22.786  1.00 28.43  ? 115 CYS B SG  1 
ATOM   3114  N  N   . PHE B 1 116 ? 12.209  -19.357 23.886  1.00 29.09  ? 116 PHE B N   1 
ATOM   3115  C  CA  . PHE B 1 116 ? 11.121  -20.181 24.380  1.00 28.15  ? 116 PHE B CA  1 
ATOM   3116  C  C   . PHE B 1 116 ? 9.912   -20.063 23.458  1.00 29.04  ? 116 PHE B C   1 
ATOM   3117  O  O   . PHE B 1 116 ? 9.188   -21.019 23.232  1.00 32.24  ? 116 PHE B O   1 
ATOM   3118  C  CB  . PHE B 1 116 ? 10.804  -19.744 25.803  1.00 30.98  ? 116 PHE B CB  1 
ATOM   3119  C  CG  . PHE B 1 116 ? 9.885   -20.721 26.504  1.00 30.50  ? 116 PHE B CG  1 
ATOM   3120  C  CD1 . PHE B 1 116 ? 10.411  -21.816 27.194  1.00 30.19  ? 116 PHE B CD1 1 
ATOM   3121  C  CD2 . PHE B 1 116 ? 8.508   -20.521 26.483  1.00 32.08  ? 116 PHE B CD2 1 
ATOM   3122  C  CE1 . PHE B 1 116 ? 9.583   -22.732 27.791  1.00 31.54  ? 116 PHE B CE1 1 
ATOM   3123  C  CE2 . PHE B 1 116 ? 7.665   -21.436 27.104  1.00 34.58  ? 116 PHE B CE2 1 
ATOM   3124  C  CZ  . PHE B 1 116 ? 8.201   -22.556 27.735  1.00 33.21  ? 116 PHE B CZ  1 
ATOM   3125  N  N   . ALA B 1 117 ? 9.667   -18.877 22.915  1.00 29.04  ? 117 ALA B N   1 
ATOM   3126  C  CA  . ALA B 1 117 ? 8.503   -18.675 22.071  1.00 27.47  ? 117 ALA B CA  1 
ATOM   3127  C  C   . ALA B 1 117 ? 8.650   -19.522 20.814  1.00 26.65  ? 117 ALA B C   1 
ATOM   3128  O  O   . ALA B 1 117 ? 7.703   -20.178 20.414  1.00 26.87  ? 117 ALA B O   1 
ATOM   3129  C  CB  . ALA B 1 117 ? 8.344   -17.198 21.760  1.00 26.99  ? 117 ALA B CB  1 
ATOM   3130  N  N   . LEU B 1 118 ? 9.851   -19.518 20.215  1.00 28.23  ? 118 LEU B N   1 
ATOM   3131  C  CA  . LEU B 1 118 ? 10.104  -20.304 19.020  1.00 25.79  ? 118 LEU B CA  1 
ATOM   3132  C  C   . LEU B 1 118 ? 10.053  -21.797 19.347  1.00 23.92  ? 118 LEU B C   1 
ATOM   3133  O  O   . LEU B 1 118 ? 9.491   -22.590 18.596  1.00 25.91  ? 118 LEU B O   1 
ATOM   3134  C  CB  . LEU B 1 118 ? 11.444  -19.888 18.409  1.00 30.48  ? 118 LEU B CB  1 
ATOM   3135  C  CG  . LEU B 1 118 ? 11.874  -20.678 17.153  1.00 34.35  ? 118 LEU B CG  1 
ATOM   3136  C  CD1 . LEU B 1 118 ? 10.773  -20.606 16.074  1.00 36.61  ? 118 LEU B CD1 1 
ATOM   3137  C  CD2 . LEU B 1 118 ? 13.168  -20.214 16.543  1.00 34.02  ? 118 LEU B CD2 1 
ATOM   3138  N  N   . ALA B 1 119 ? 10.649  -22.217 20.468  1.00 24.61  ? 119 ALA B N   1 
ATOM   3139  C  CA  . ALA B 1 119 ? 10.603  -23.628 20.839  1.00 26.53  ? 119 ALA B CA  1 
ATOM   3140  C  C   . ALA B 1 119 ? 9.157   -24.093 21.007  1.00 27.81  ? 119 ALA B C   1 
ATOM   3141  O  O   . ALA B 1 119 ? 8.813   -25.193 20.595  1.00 25.86  ? 119 ALA B O   1 
ATOM   3142  C  CB  . ALA B 1 119 ? 11.404  -23.861 22.097  1.00 24.86  ? 119 ALA B CB  1 
ATOM   3143  N  N   . THR B 1 120 ? 8.322   -23.255 21.633  1.00 28.05  ? 120 THR B N   1 
ATOM   3144  C  CA  . THR B 1 120 ? 6.914   -23.551 21.816  1.00 27.75  ? 120 THR B CA  1 
ATOM   3145  C  C   . THR B 1 120 ? 6.259   -23.794 20.465  1.00 31.36  ? 120 THR B C   1 
ATOM   3146  O  O   . THR B 1 120 ? 5.494   -24.735 20.337  1.00 27.97  ? 120 THR B O   1 
ATOM   3147  C  CB  . THR B 1 120 ? 6.210   -22.394 22.508  1.00 29.02  ? 120 THR B CB  1 
ATOM   3148  O  OG1 . THR B 1 120 ? 6.753   -22.354 23.820  1.00 29.95  ? 120 THR B OG1 1 
ATOM   3149  C  CG2 . THR B 1 120 ? 4.715   -22.638 22.633  1.00 30.19  ? 120 THR B CG2 1 
ATOM   3150  N  N   . GLU B 1 121 ? 6.519   -22.913 19.487  1.00 31.82  ? 121 GLU B N   1 
ATOM   3151  C  CA  . GLU B 1 121 ? 5.907   -23.068 18.181  1.00 32.09  ? 121 GLU B CA  1 
ATOM   3152  C  C   . GLU B 1 121 ? 6.354   -24.374 17.523  1.00 32.62  ? 121 GLU B C   1 
ATOM   3153  O  O   . GLU B 1 121 ? 5.554   -25.104 16.933  1.00 28.04  ? 121 GLU B O   1 
ATOM   3154  C  CB  . GLU B 1 121 ? 6.196   -21.943 17.193  1.00 31.05  ? 121 GLU B CB  1 
ATOM   3155  C  CG  . GLU B 1 121 ? 5.505   -20.628 17.548  1.00 34.77  ? 121 GLU B CG  1 
ATOM   3156  C  CD  . GLU B 1 121 ? 3.998   -20.598 17.464  1.00 34.24  ? 121 GLU B CD  1 
ATOM   3157  O  OE1 . GLU B 1 121 ? 3.423   -21.495 16.845  1.00 31.54  ? 121 GLU B OE1 1 
ATOM   3158  O  OE2 . GLU B 1 121 ? 3.439   -19.703 18.107  1.00 40.36  ? 121 GLU B OE2 1 
ATOM   3159  N  N   . ILE B 1 122 ? 7.642   -24.671 17.617  1.00 29.63  ? 122 ILE B N   1 
ATOM   3160  C  CA  . ILE B 1 122 ? 8.155   -25.860 16.978  1.00 31.94  ? 122 ILE B CA  1 
ATOM   3161  C  C   . ILE B 1 122 ? 7.524   -27.096 17.617  1.00 30.62  ? 122 ILE B C   1 
ATOM   3162  O  O   . ILE B 1 122 ? 6.945   -27.916 16.925  1.00 29.20  ? 122 ILE B O   1 
ATOM   3163  C  CB  . ILE B 1 122 ? 9.688   -25.856 16.993  1.00 28.40  ? 122 ILE B CB  1 
ATOM   3164  C  CG1 . ILE B 1 122 ? 10.221  -24.815 16.002  1.00 26.04  ? 122 ILE B CG1 1 
ATOM   3165  C  CG2 . ILE B 1 122 ? 10.223  -27.252 16.675  1.00 30.09  ? 122 ILE B CG2 1 
ATOM   3166  C  CD1 . ILE B 1 122 ? 11.691  -24.511 16.193  1.00 29.04  ? 122 ILE B CD1 1 
ATOM   3167  N  N   . MET B 1 123 ? 7.612   -27.217 18.934  1.00 30.95  ? 123 MET B N   1 
ATOM   3168  C  CA  . MET B 1 123 ? 7.112   -28.408 19.603  1.00 37.00  ? 123 MET B CA  1 
ATOM   3169  C  C   . MET B 1 123 ? 5.600   -28.541 19.492  1.00 34.15  ? 123 MET B C   1 
ATOM   3170  O  O   . MET B 1 123 ? 5.086   -29.645 19.619  1.00 36.50  ? 123 MET B O   1 
ATOM   3171  C  CB  . MET B 1 123 ? 7.474   -28.401 21.091  1.00 44.57  ? 123 MET B CB  1 
ATOM   3172  C  CG  . MET B 1 123 ? 8.929   -28.713 21.332  1.00 53.05  ? 123 MET B CG  1 
ATOM   3173  S  SD  . MET B 1 123 ? 9.401   -30.387 20.858  1.00 53.72  ? 123 MET B SD  1 
ATOM   3174  C  CE  . MET B 1 123 ? 8.045   -31.321 21.608  1.00 46.04  ? 123 MET B CE  1 
ATOM   3175  N  N   . GLY B 1 124 ? 4.903   -27.413 19.311  1.00 34.40  ? 124 GLY B N   1 
ATOM   3176  C  CA  . GLY B 1 124 ? 3.464   -27.393 19.094  1.00 33.39  ? 124 GLY B CA  1 
ATOM   3177  C  C   . GLY B 1 124 ? 3.084   -28.152 17.832  1.00 34.45  ? 124 GLY B C   1 
ATOM   3178  O  O   . GLY B 1 124 ? 2.146   -28.935 17.853  1.00 39.44  ? 124 GLY B O   1 
ATOM   3179  N  N   . ARG B 1 125 ? 3.858   -27.961 16.762  1.00 35.75  ? 125 ARG B N   1 
ATOM   3180  C  CA  . ARG B 1 125 ? 3.620   -28.611 15.483  1.00 33.59  ? 125 ARG B CA  1 
ATOM   3181  C  C   . ARG B 1 125 ? 4.069   -30.073 15.503  1.00 34.63  ? 125 ARG B C   1 
ATOM   3182  O  O   . ARG B 1 125 ? 3.730   -30.835 14.619  1.00 35.25  ? 125 ARG B O   1 
ATOM   3183  C  CB  . ARG B 1 125 ? 4.443   -27.895 14.414  1.00 35.59  ? 125 ARG B CB  1 
ATOM   3184  C  CG  . ARG B 1 125 ? 4.120   -26.411 14.278  1.00 42.89  ? 125 ARG B CG  1 
ATOM   3185  C  CD  . ARG B 1 125 ? 3.068   -25.981 13.254  1.00 46.24  ? 125 ARG B CD  1 
ATOM   3186  N  NE  . ARG B 1 125 ? 3.279   -26.768 12.034  1.00 56.35  ? 125 ARG B NE  1 
ATOM   3187  C  CZ  . ARG B 1 125 ? 3.878   -26.319 10.922  1.00 63.65  ? 125 ARG B CZ  1 
ATOM   3188  N  NH1 . ARG B 1 125 ? 4.039   -25.012 10.758  1.00 72.87  ? 125 ARG B NH1 1 
ATOM   3189  N  NH2 . ARG B 1 125 ? 4.278   -27.160 9.974   1.00 52.88  ? 125 ARG B NH2 1 
ATOM   3190  N  N   . LEU B 1 126 ? 4.901   -30.459 16.468  1.00 39.04  ? 126 LEU B N   1 
ATOM   3191  C  CA  . LEU B 1 126 ? 5.456   -31.798 16.493  1.00 38.75  ? 126 LEU B CA  1 
ATOM   3192  C  C   . LEU B 1 126 ? 4.795   -32.654 17.572  1.00 40.87  ? 126 LEU B C   1 
ATOM   3193  O  O   . LEU B 1 126 ? 5.191   -33.814 17.684  1.00 41.71  ? 126 LEU B O   1 
ATOM   3194  C  CB  . LEU B 1 126 ? 6.971   -31.779 16.719  1.00 33.87  ? 126 LEU B CB  1 
ATOM   3195  C  CG  . LEU B 1 126 ? 7.814   -31.144 15.615  1.00 36.64  ? 126 LEU B CG  1 
ATOM   3196  C  CD1 . LEU B 1 126 ? 9.282   -31.148 15.992  1.00 38.14  ? 126 LEU B CD1 1 
ATOM   3197  C  CD2 . LEU B 1 126 ? 7.647   -31.848 14.283  1.00 40.38  ? 126 LEU B CD2 1 
ATOM   3198  N  N   . ARG B 1 127 ? 3.885   -32.089 18.390  1.00 41.04  ? 127 ARG B N   1 
ATOM   3199  C  CA  . ARG B 1 127 ? 3.189   -32.826 19.446  1.00 40.87  ? 127 ARG B CA  1 
ATOM   3200  C  C   . ARG B 1 127 ? 2.660   -34.114 18.804  1.00 44.58  ? 127 ARG B C   1 
ATOM   3201  O  O   . ARG B 1 127 ? 2.093   -34.079 17.705  1.00 43.64  ? 127 ARG B O   1 
ATOM   3202  C  CB  . ARG B 1 127 ? 1.982   -32.103 20.088  1.00 40.11  ? 127 ARG B CB  1 
ATOM   3203  C  CG  . ARG B 1 127 ? 2.111   -31.096 21.230  1.00 37.69  ? 127 ARG B CG  1 
ATOM   3204  N  N   . GLY B 1 128 ? 2.904   -35.272 19.421  1.00 39.52  ? 128 GLY B N   1 
ATOM   3205  C  CA  . GLY B 1 128 ? 2.375   -36.495 18.852  1.00 35.99  ? 128 GLY B CA  1 
ATOM   3206  C  C   . GLY B 1 128 ? 3.345   -37.204 17.906  1.00 35.33  ? 128 GLY B C   1 
ATOM   3207  O  O   . GLY B 1 128 ? 3.221   -38.388 17.718  1.00 41.68  ? 128 GLY B O   1 
ATOM   3208  N  N   . ALA B 1 129 ? 4.317   -36.523 17.306  1.00 38.04  ? 129 ALA B N   1 
ATOM   3209  C  CA  . ALA B 1 129 ? 5.210   -37.153 16.340  1.00 38.06  ? 129 ALA B CA  1 
ATOM   3210  C  C   . ALA B 1 129 ? 6.597   -37.502 16.901  1.00 38.42  ? 129 ALA B C   1 
ATOM   3211  O  O   . ALA B 1 129 ? 7.335   -38.291 16.290  1.00 31.41  ? 129 ALA B O   1 
ATOM   3212  C  CB  . ALA B 1 129 ? 5.356   -36.237 15.144  1.00 40.83  ? 129 ALA B CB  1 
ATOM   3213  N  N   . VAL B 1 130 ? 6.985   -36.859 18.017  1.00 40.09  ? 130 VAL B N   1 
ATOM   3214  C  CA  . VAL B 1 130 ? 8.349   -36.942 18.513  1.00 41.36  ? 130 VAL B CA  1 
ATOM   3215  C  C   . VAL B 1 130 ? 8.322   -37.155 20.021  1.00 40.78  ? 130 VAL B C   1 
ATOM   3216  O  O   . VAL B 1 130 ? 7.320   -36.929 20.663  1.00 42.18  ? 130 VAL B O   1 
ATOM   3217  C  CB  . VAL B 1 130 ? 9.180   -35.694 18.167  1.00 38.69  ? 130 VAL B CB  1 
ATOM   3218  C  CG1 . VAL B 1 130 ? 9.180   -35.404 16.680  1.00 44.94  ? 130 VAL B CG1 1 
ATOM   3219  C  CG2 . VAL B 1 130 ? 8.723   -34.464 18.925  1.00 38.69  ? 130 VAL B CG2 1 
ATOM   3220  N  N   . THR B 1 131 ? 9.451   -37.569 20.582  1.00 45.12  ? 131 THR B N   1 
ATOM   3221  C  CA  . THR B 1 131 ? 9.593   -37.729 22.018  1.00 45.85  ? 131 THR B CA  1 
ATOM   3222  C  C   . THR B 1 131 ? 10.801  -36.894 22.438  1.00 45.70  ? 131 THR B C   1 
ATOM   3223  O  O   . THR B 1 131 ? 11.896  -37.055 21.883  1.00 46.03  ? 131 THR B O   1 
ATOM   3224  C  CB  . THR B 1 131 ? 9.753   -39.216 22.349  1.00 47.42  ? 131 THR B CB  1 
ATOM   3225  O  OG1 . THR B 1 131 ? 8.498   -39.813 22.005  1.00 51.70  ? 131 THR B OG1 1 
ATOM   3226  C  CG2 . THR B 1 131 ? 10.099  -39.440 23.809  1.00 42.96  ? 131 THR B CG2 1 
ATOM   3227  N  N   . PRO B 1 132 ? 10.656  -35.990 23.426  1.00 44.70  ? 132 PRO B N   1 
ATOM   3228  C  CA  . PRO B 1 132 ? 11.777  -35.162 23.851  1.00 45.82  ? 132 PRO B CA  1 
ATOM   3229  C  C   . PRO B 1 132 ? 12.815  -36.052 24.527  1.00 41.25  ? 132 PRO B C   1 
ATOM   3230  O  O   . PRO B 1 132 ? 12.462  -36.897 25.321  1.00 39.13  ? 132 PRO B O   1 
ATOM   3231  C  CB  . PRO B 1 132 ? 11.147  -34.139 24.798  1.00 42.48  ? 132 PRO B CB  1 
ATOM   3232  C  CG  . PRO B 1 132 ? 9.667   -34.305 24.618  1.00 40.95  ? 132 PRO B CG  1 
ATOM   3233  C  CD  . PRO B 1 132 ? 9.460   -35.749 24.230  1.00 40.07  ? 132 PRO B CD  1 
ATOM   3234  N  N   . GLN B 1 133 ? 14.085  -35.868 24.185  1.00 36.50  ? 133 GLN B N   1 
ATOM   3235  C  CA  . GLN B 1 133 ? 15.178  -36.534 24.872  1.00 38.82  ? 133 GLN B CA  1 
ATOM   3236  C  C   . GLN B 1 133 ? 15.950  -35.590 25.796  1.00 39.64  ? 133 GLN B C   1 
ATOM   3237  O  O   . GLN B 1 133 ? 16.590  -36.077 26.731  1.00 35.56  ? 133 GLN B O   1 
ATOM   3238  C  CB  . GLN B 1 133 ? 16.266  -37.021 23.918  1.00 38.90  ? 133 GLN B CB  1 
ATOM   3239  C  CG  . GLN B 1 133 ? 15.786  -38.072 22.935  1.00 47.13  ? 133 GLN B CG  1 
ATOM   3240  C  CD  . GLN B 1 133 ? 15.267  -39.293 23.662  1.00 50.77  ? 133 GLN B CD  1 
ATOM   3241  O  OE1 . GLN B 1 133 ? 15.893  -39.752 24.625  1.00 49.88  ? 133 GLN B OE1 1 
ATOM   3242  N  NE2 . GLN B 1 133 ? 14.098  -39.768 23.248  1.00 43.90  ? 133 GLN B NE2 1 
ATOM   3243  N  N   . ASP B 1 134 ? 16.037  -34.293 25.451  1.00 34.04  ? 134 ASP B N   1 
ATOM   3244  C  CA  . ASP B 1 134 ? 16.861  -33.351 26.198  1.00 34.37  ? 134 ASP B CA  1 
ATOM   3245  C  C   . ASP B 1 134 ? 16.331  -31.958 25.880  1.00 35.84  ? 134 ASP B C   1 
ATOM   3246  O  O   . ASP B 1 134 ? 15.914  -31.678 24.741  1.00 40.11  ? 134 ASP B O   1 
ATOM   3247  C  CB  . ASP B 1 134 ? 18.346  -33.482 25.872  1.00 33.30  ? 134 ASP B CB  1 
ATOM   3248  C  CG  . ASP B 1 134 ? 19.319  -32.961 26.912  1.00 33.66  ? 134 ASP B CG  1 
ATOM   3249  O  OD1 . ASP B 1 134 ? 18.869  -32.728 28.017  1.00 29.42  ? 134 ASP B OD1 1 
ATOM   3250  O  OD2 . ASP B 1 134 ? 20.528  -32.813 26.605  1.00 35.05  ? 134 ASP B OD2 1 
ATOM   3251  N  N   . GLU B 1 135 ? 16.286  -31.112 26.918  1.00 35.22  ? 135 GLU B N   1 
ATOM   3252  C  CA  . GLU B 1 135 ? 15.920  -29.715 26.768  1.00 31.41  ? 135 GLU B CA  1 
ATOM   3253  C  C   . GLU B 1 135 ? 16.764  -28.925 27.753  1.00 28.16  ? 135 GLU B C   1 
ATOM   3254  O  O   . GLU B 1 135 ? 16.726  -29.188 28.930  1.00 28.87  ? 135 GLU B O   1 
ATOM   3255  C  CB  . GLU B 1 135 ? 14.432  -29.495 27.034  1.00 30.59  ? 135 GLU B CB  1 
ATOM   3256  C  CG  . GLU B 1 135 ? 14.001  -28.041 26.912  1.00 34.46  ? 135 GLU B CG  1 
ATOM   3257  C  CD  . GLU B 1 135 ? 12.578  -27.818 27.414  1.00 36.36  ? 135 GLU B CD  1 
ATOM   3258  O  OE1 . GLU B 1 135 ? 11.987  -28.840 27.857  1.00 36.71  ? 135 GLU B OE1 1 
ATOM   3259  O  OE2 . GLU B 1 135 ? 12.083  -26.656 27.407  1.00 32.17  ? 135 GLU B OE2 1 
ATOM   3260  N  N   . VAL B 1 136 ? 17.566  -27.991 27.272  1.00 26.56  ? 136 VAL B N   1 
ATOM   3261  C  CA  . VAL B 1 136 ? 18.487  -27.255 28.115  1.00 29.29  ? 136 VAL B CA  1 
ATOM   3262  C  C   . VAL B 1 136 ? 18.307  -25.763 27.810  1.00 29.35  ? 136 VAL B C   1 
ATOM   3263  O  O   . VAL B 1 136 ? 18.255  -25.362 26.652  1.00 28.62  ? 136 VAL B O   1 
ATOM   3264  C  CB  . VAL B 1 136 ? 19.938  -27.714 27.878  1.00 31.21  ? 136 VAL B CB  1 
ATOM   3265  C  CG1 . VAL B 1 136 ? 20.944  -26.853 28.610  1.00 31.65  ? 136 VAL B CG1 1 
ATOM   3266  C  CG2 . VAL B 1 136 ? 20.151  -29.149 28.269  1.00 32.09  ? 136 VAL B CG2 1 
ATOM   3267  N  N   . HIS B 1 137 ? 18.162  -24.963 28.878  1.00 27.84  ? 137 HIS B N   1 
ATOM   3268  C  CA  . HIS B 1 137 ? 18.040  -23.521 28.798  1.00 24.06  ? 137 HIS B CA  1 
ATOM   3269  C  C   . HIS B 1 137 ? 19.379  -23.000 29.266  1.00 24.52  ? 137 HIS B C   1 
ATOM   3270  O  O   . HIS B 1 137 ? 19.764  -23.228 30.402  1.00 21.70  ? 137 HIS B O   1 
ATOM   3271  C  CB  . HIS B 1 137 ? 16.892  -22.987 29.647  1.00 22.61  ? 137 HIS B CB  1 
ATOM   3272  C  CG  . HIS B 1 137 ? 15.562  -23.520 29.272  1.00 25.51  ? 137 HIS B CG  1 
ATOM   3273  N  ND1 . HIS B 1 137 ? 14.412  -23.012 29.839  1.00 25.84  ? 137 HIS B ND1 1 
ATOM   3274  C  CD2 . HIS B 1 137 ? 15.168  -24.515 28.433  1.00 24.93  ? 137 HIS B CD2 1 
ATOM   3275  C  CE1 . HIS B 1 137 ? 13.366  -23.674 29.339  1.00 26.75  ? 137 HIS B CE1 1 
ATOM   3276  N  NE2 . HIS B 1 137 ? 13.795  -24.582 28.483  1.00 26.05  ? 137 HIS B NE2 1 
ATOM   3277  N  N   . GLY B 1 138 ? 20.114  -22.398 28.329  1.00 26.63  ? 138 GLY B N   1 
ATOM   3278  C  CA  . GLY B 1 138 ? 21.460  -21.950 28.602  1.00 26.55  ? 138 GLY B CA  1 
ATOM   3279  C  C   . GLY B 1 138 ? 21.492  -20.440 28.788  1.00 25.22  ? 138 GLY B C   1 
ATOM   3280  O  O   . GLY B 1 138 ? 20.666  -19.736 28.204  1.00 22.14  ? 138 GLY B O   1 
ATOM   3281  N  N   . PHE B 1 139 ? 22.501  -19.982 29.526  1.00 24.03  ? 139 PHE B N   1 
ATOM   3282  C  CA  . PHE B 1 139 ? 22.730  -18.558 29.726  1.00 27.33  ? 139 PHE B CA  1 
ATOM   3283  C  C   . PHE B 1 139 ? 24.233  -18.294 29.750  1.00 28.54  ? 139 PHE B C   1 
ATOM   3284  O  O   . PHE B 1 139 ? 24.942  -18.992 30.442  1.00 35.15  ? 139 PHE B O   1 
ATOM   3285  C  CB  . PHE B 1 139 ? 22.082  -18.102 31.043  1.00 30.62  ? 139 PHE B CB  1 
ATOM   3286  C  CG  . PHE B 1 139 ? 22.288  -19.040 32.231  1.00 36.72  ? 139 PHE B CG  1 
ATOM   3287  C  CD1 . PHE B 1 139 ? 21.391  -20.083 32.450  1.00 37.16  ? 139 PHE B CD1 1 
ATOM   3288  C  CD2 . PHE B 1 139 ? 23.379  -18.936 33.091  1.00 44.40  ? 139 PHE B CD2 1 
ATOM   3289  C  CE1 . PHE B 1 139 ? 21.553  -20.973 33.492  1.00 35.36  ? 139 PHE B CE1 1 
ATOM   3290  C  CE2 . PHE B 1 139 ? 23.554  -19.850 34.126  1.00 41.48  ? 139 PHE B CE2 1 
ATOM   3291  C  CZ  . PHE B 1 139 ? 22.630  -20.854 34.325  1.00 38.84  ? 139 PHE B CZ  1 
ATOM   3292  N  N   . LYS B 1 140 ? 24.732  -17.302 28.998  1.00 31.31  ? 140 LYS B N   1 
ATOM   3293  C  CA  . LYS B 1 140 ? 26.142  -16.943 29.025  1.00 32.90  ? 140 LYS B CA  1 
ATOM   3294  C  C   . LYS B 1 140 ? 26.320  -16.031 30.226  1.00 29.69  ? 140 LYS B C   1 
ATOM   3295  O  O   . LYS B 1 140 ? 25.436  -15.253 30.517  1.00 24.78  ? 140 LYS B O   1 
ATOM   3296  C  CB  . LYS B 1 140 ? 26.548  -16.321 27.675  1.00 49.40  ? 140 LYS B CB  1 
ATOM   3297  C  CG  . LYS B 1 140 ? 27.988  -16.558 27.182  1.00 62.42  ? 140 LYS B CG  1 
ATOM   3298  C  CD  . LYS B 1 140 ? 28.490  -18.007 27.179  1.00 71.05  ? 140 LYS B CD  1 
ATOM   3299  C  CE  . LYS B 1 140 ? 29.978  -18.236 27.244  1.00 65.95  ? 140 LYS B CE  1 
ATOM   3300  N  NZ  . LYS B 1 140 ? 30.599  -17.920 25.950  1.00 59.28  ? 140 LYS B NZ  1 
ATOM   3301  N  N   . TYR B 1 141 ? 27.440  -16.163 30.938  1.00 31.08  ? 141 TYR B N   1 
ATOM   3302  C  CA  . TYR B 1 141 ? 27.781  -15.270 32.037  1.00 30.13  ? 141 TYR B CA  1 
ATOM   3303  C  C   . TYR B 1 141 ? 28.269  -13.951 31.463  1.00 35.75  ? 141 TYR B C   1 
ATOM   3304  O  O   . TYR B 1 141 ? 28.523  -13.835 30.277  1.00 30.29  ? 141 TYR B O   1 
ATOM   3305  C  CB  . TYR B 1 141 ? 28.850  -15.864 32.937  1.00 30.19  ? 141 TYR B CB  1 
ATOM   3306  C  CG  . TYR B 1 141 ? 28.315  -16.846 33.966  1.00 29.66  ? 141 TYR B CG  1 
ATOM   3307  C  CD1 . TYR B 1 141 ? 27.793  -16.423 35.150  1.00 32.88  ? 141 TYR B CD1 1 
ATOM   3308  C  CD2 . TYR B 1 141 ? 28.374  -18.202 33.750  1.00 36.31  ? 141 TYR B CD2 1 
ATOM   3309  C  CE1 . TYR B 1 141 ? 27.315  -17.315 36.084  1.00 36.63  ? 141 TYR B CE1 1 
ATOM   3310  C  CE2 . TYR B 1 141 ? 27.904  -19.119 34.669  1.00 35.74  ? 141 TYR B CE2 1 
ATOM   3311  C  CZ  . TYR B 1 141 ? 27.367  -18.666 35.845  1.00 37.59  ? 141 TYR B CZ  1 
ATOM   3312  O  OH  . TYR B 1 141 ? 26.898  -19.530 36.783  1.00 46.49  ? 141 TYR B OH  1 
ATOM   3313  N  N   . PHE B 1 142 ? 28.376  -12.923 32.294  1.00 49.87  ? 142 PHE B N   1 
ATOM   3314  C  CA  . PHE B 1 142 ? 28.286  -11.582 31.744  1.00 53.13  ? 142 PHE B CA  1 
ATOM   3315  C  C   . PHE B 1 142 ? 29.607  -11.241 31.037  1.00 45.26  ? 142 PHE B C   1 
ATOM   3316  O  O   . PHE B 1 142 ? 29.558  -10.345 30.186  1.00 45.39  ? 142 PHE B O   1 
ATOM   3317  C  CB  . PHE B 1 142 ? 27.726  -10.558 32.760  1.00 61.33  ? 142 PHE B CB  1 
ATOM   3318  C  CG  . PHE B 1 142 ? 28.773  -9.900  33.647  1.00 74.91  ? 142 PHE B CG  1 
ATOM   3319  C  CD1 . PHE B 1 142 ? 29.201  -10.538 34.812  1.00 92.20  ? 142 PHE B CD1 1 
ATOM   3320  C  CD2 . PHE B 1 142 ? 29.383  -8.691  33.276  1.00 79.49  ? 142 PHE B CD2 1 
ATOM   3321  C  CE1 . PHE B 1 142 ? 30.207  -9.969  35.588  1.00 103.12 ? 142 PHE B CE1 1 
ATOM   3322  C  CE2 . PHE B 1 142 ? 30.417  -8.149  34.027  1.00 82.76  ? 142 PHE B CE2 1 
ATOM   3323  C  CZ  . PHE B 1 142 ? 30.820  -8.781  35.185  1.00 94.05  ? 142 PHE B CZ  1 
ATOM   3324  N  N   . ASP B 1 143 ? 30.752  -11.929 31.290  1.00 37.46  ? 143 ASP B N   1 
ATOM   3325  C  CA  . ASP B 1 143 ? 31.919  -11.574 30.483  1.00 42.63  ? 143 ASP B CA  1 
ATOM   3326  C  C   . ASP B 1 143 ? 32.389  -12.758 29.667  1.00 35.31  ? 143 ASP B C   1 
ATOM   3327  O  O   . ASP B 1 143 ? 33.569  -13.023 29.599  1.00 37.98  ? 143 ASP B O   1 
ATOM   3328  C  CB  . ASP B 1 143 ? 33.067  -10.947 31.248  1.00 45.09  ? 143 ASP B CB  1 
ATOM   3329  C  CG  . ASP B 1 143 ? 33.291  -11.594 32.594  1.00 62.33  ? 143 ASP B CG  1 
ATOM   3330  O  OD1 . ASP B 1 143 ? 32.325  -12.311 33.095  1.00 52.12  ? 143 ASP B OD1 1 
ATOM   3331  O  OD2 . ASP B 1 143 ? 34.440  -11.387 33.087  1.00 79.09  ? 143 ASP B OD2 1 
ATOM   3332  N  N   . GLU B 1 144 ? 31.443  -13.385 28.977  1.00 30.80  ? 144 GLU B N   1 
ATOM   3333  C  CA  . GLU B 1 144 ? 31.650  -14.558 28.151  1.00 29.08  ? 144 GLU B CA  1 
ATOM   3334  C  C   . GLU B 1 144 ? 32.316  -15.693 28.928  1.00 29.36  ? 144 GLU B C   1 
ATOM   3335  O  O   . GLU B 1 144 ? 32.888  -16.586 28.309  1.00 30.08  ? 144 GLU B O   1 
ATOM   3336  C  CB  . GLU B 1 144 ? 32.366  -14.069 26.901  1.00 32.56  ? 144 GLU B CB  1 
ATOM   3337  C  CG  . GLU B 1 144 ? 31.507  -13.075 26.113  1.00 33.12  ? 144 GLU B CG  1 
ATOM   3338  C  CD  . GLU B 1 144 ? 30.312  -13.741 25.455  1.00 33.33  ? 144 GLU B CD  1 
ATOM   3339  O  OE1 . GLU B 1 144 ? 30.277  -14.955 25.120  1.00 31.47  ? 144 GLU B OE1 1 
ATOM   3340  O  OE2 . GLU B 1 144 ? 29.352  -12.974 25.354  1.00 37.24  ? 144 GLU B OE2 1 
ATOM   3341  N  N   . ARG B 1 145 ? 32.166  -15.715 30.268  1.00 28.24  ? 145 ARG B N   1 
ATOM   3342  C  CA  . ARG B 1 145 ? 32.705  -16.813 31.052  1.00 25.74  ? 145 ARG B CA  1 
ATOM   3343  C  C   . ARG B 1 145 ? 31.754  -18.006 31.131  1.00 26.03  ? 145 ARG B C   1 
ATOM   3344  O  O   . ARG B 1 145 ? 30.541  -17.906 30.886  1.00 24.23  ? 145 ARG B O   1 
ATOM   3345  C  CB  . ARG B 1 145 ? 33.115  -16.358 32.438  1.00 26.78  ? 145 ARG B CB  1 
ATOM   3346  C  CG  . ARG B 1 145 ? 34.208  -15.320 32.306  1.00 28.44  ? 145 ARG B CG  1 
ATOM   3347  C  CD  . ARG B 1 145 ? 34.877  -15.015 33.632  1.00 28.42  ? 145 ARG B CD  1 
ATOM   3348  N  NE  . ARG B 1 145 ? 35.828  -13.903 33.517  1.00 30.81  ? 145 ARG B NE  1 
ATOM   3349  C  CZ  . ARG B 1 145 ? 37.125  -14.065 33.392  1.00 33.18  ? 145 ARG B CZ  1 
ATOM   3350  N  NH1 . ARG B 1 145 ? 37.976  -13.084 33.507  1.00 35.48  ? 145 ARG B NH1 1 
ATOM   3351  N  NH2 . ARG B 1 145 ? 37.637  -15.267 33.290  1.00 35.36  ? 145 ARG B NH2 1 
ATOM   3352  N  N   . ASP B 1 146 ? 32.356  -19.177 31.386  1.00 24.79  ? 146 ASP B N   1 
ATOM   3353  C  CA  . ASP B 1 146 ? 31.587  -20.403 31.470  1.00 31.87  ? 146 ASP B CA  1 
ATOM   3354  C  C   . ASP B 1 146 ? 31.464  -20.784 32.931  1.00 26.46  ? 146 ASP B C   1 
ATOM   3355  O  O   . ASP B 1 146 ? 31.848  -20.012 33.794  1.00 23.82  ? 146 ASP B O   1 
ATOM   3356  C  CB  . ASP B 1 146 ? 32.137  -21.507 30.571  1.00 31.63  ? 146 ASP B CB  1 
ATOM   3357  C  CG  . ASP B 1 146 ? 33.551  -21.895 30.913  1.00 27.36  ? 146 ASP B CG  1 
ATOM   3358  O  OD1 . ASP B 1 146 ? 33.920  -21.686 32.063  1.00 26.07  ? 146 ASP B OD1 1 
ATOM   3359  O  OD2 . ASP B 1 146 ? 34.259  -22.356 30.012  1.00 26.41  ? 146 ASP B OD2 1 
ATOM   3360  N  N   . MET B 1 147 ? 30.955  -21.996 33.157  1.00 27.75  ? 147 MET B N   1 
ATOM   3361  C  CA  . MET B 1 147 ? 30.648  -22.440 34.502  1.00 32.30  ? 147 MET B CA  1 
ATOM   3362  C  C   . MET B 1 147 ? 31.931  -22.622 35.332  1.00 33.10  ? 147 MET B C   1 
ATOM   3363  O  O   . MET B 1 147 ? 31.878  -22.603 36.544  1.00 29.54  ? 147 MET B O   1 
ATOM   3364  C  CB  . MET B 1 147 ? 29.836  -23.738 34.386  1.00 32.85  ? 147 MET B CB  1 
ATOM   3365  C  CG  . MET B 1 147 ? 29.147  -24.157 35.662  1.00 34.42  ? 147 MET B CG  1 
ATOM   3366  S  SD  . MET B 1 147 ? 27.989  -22.919 36.265  1.00 35.26  ? 147 MET B SD  1 
ATOM   3367  C  CE  . MET B 1 147 ? 26.433  -23.285 35.447  1.00 41.36  ? 147 MET B CE  1 
ATOM   3368  N  N   . LEU B 1 148 ? 33.092  -22.804 34.686  1.00 30.58  ? 148 LEU B N   1 
ATOM   3369  C  CA  . LEU B 1 148 ? 34.341  -22.972 35.400  1.00 27.22  ? 148 LEU B CA  1 
ATOM   3370  C  C   . LEU B 1 148 ? 35.014  -21.620 35.617  1.00 25.28  ? 148 LEU B C   1 
ATOM   3371  O  O   . LEU B 1 148 ? 36.116  -21.568 36.134  1.00 27.64  ? 148 LEU B O   1 
ATOM   3372  C  CB  . LEU B 1 148 ? 35.271  -23.875 34.588  1.00 27.00  ? 148 LEU B CB  1 
ATOM   3373  C  CG  . LEU B 1 148 ? 34.751  -25.269 34.245  1.00 28.22  ? 148 LEU B CG  1 
ATOM   3374  C  CD1 . LEU B 1 148 ? 35.772  -26.029 33.417  1.00 28.92  ? 148 LEU B CD1 1 
ATOM   3375  C  CD2 . LEU B 1 148 ? 34.470  -26.029 35.507  1.00 31.69  ? 148 LEU B CD2 1 
ATOM   3376  N  N   . GLY B 1 149 ? 34.418  -20.526 35.156  1.00 23.20  ? 149 GLY B N   1 
ATOM   3377  C  CA  . GLY B 1 149 ? 34.956  -19.214 35.445  1.00 20.66  ? 149 GLY B CA  1 
ATOM   3378  C  C   . GLY B 1 149 ? 35.944  -18.717 34.394  1.00 24.63  ? 149 GLY B C   1 
ATOM   3379  O  O   . GLY B 1 149 ? 36.552  -17.678 34.600  1.00 25.63  ? 149 GLY B O   1 
ATOM   3380  N  N   . PHE B 1 150 ? 36.100  -19.440 33.276  1.00 26.11  ? 150 PHE B N   1 
ATOM   3381  C  CA  . PHE B 1 150 ? 37.036  -19.095 32.223  1.00 29.45  ? 150 PHE B CA  1 
ATOM   3382  C  C   . PHE B 1 150 ? 36.299  -18.471 31.051  1.00 29.21  ? 150 PHE B C   1 
ATOM   3383  O  O   . PHE B 1 150 ? 35.195  -18.878 30.739  1.00 30.34  ? 150 PHE B O   1 
ATOM   3384  C  CB  . PHE B 1 150 ? 37.823  -20.322 31.736  1.00 32.69  ? 150 PHE B CB  1 
ATOM   3385  C  CG  . PHE B 1 150 ? 39.031  -20.594 32.612  1.00 34.30  ? 150 PHE B CG  1 
ATOM   3386  C  CD1 . PHE B 1 150 ? 38.865  -21.100 33.882  1.00 30.13  ? 150 PHE B CD1 1 
ATOM   3387  C  CD2 . PHE B 1 150 ? 40.323  -20.270 32.191  1.00 42.73  ? 150 PHE B CD2 1 
ATOM   3388  C  CE1 . PHE B 1 150 ? 39.959  -21.314 34.700  1.00 32.57  ? 150 PHE B CE1 1 
ATOM   3389  C  CE2 . PHE B 1 150 ? 41.424  -20.473 33.020  1.00 40.14  ? 150 PHE B CE2 1 
ATOM   3390  C  CZ  . PHE B 1 150 ? 41.236  -21.009 34.267  1.00 36.54  ? 150 PHE B CZ  1 
ATOM   3391  N  N   . VAL B 1 151 ? 36.946  -17.526 30.366  1.00 30.64  ? 151 VAL B N   1 
ATOM   3392  C  CA  . VAL B 1 151 ? 36.370  -17.001 29.141  1.00 26.65  ? 151 VAL B CA  1 
ATOM   3393  C  C   . VAL B 1 151 ? 36.367  -18.129 28.120  1.00 26.81  ? 151 VAL B C   1 
ATOM   3394  O  O   . VAL B 1 151 ? 37.367  -18.863 27.990  1.00 34.03  ? 151 VAL B O   1 
ATOM   3395  C  CB  . VAL B 1 151 ? 37.161  -15.791 28.637  1.00 26.12  ? 151 VAL B CB  1 
ATOM   3396  C  CG1 . VAL B 1 151 ? 36.543  -15.233 27.381  1.00 26.83  ? 151 VAL B CG1 1 
ATOM   3397  C  CG2 . VAL B 1 151 ? 37.324  -14.710 29.683  1.00 27.97  ? 151 VAL B CG2 1 
ATOM   3398  N  N   . ASP B 1 152 ? 35.238  -18.226 27.413  1.00 24.72  ? 152 ASP B N   1 
ATOM   3399  C  CA  . ASP B 1 152 ? 34.891  -19.389 26.606  1.00 24.31  ? 152 ASP B CA  1 
ATOM   3400  C  C   . ASP B 1 152 ? 34.412  -18.890 25.252  1.00 24.45  ? 152 ASP B C   1 
ATOM   3401  O  O   . ASP B 1 152 ? 33.378  -18.259 25.173  1.00 24.47  ? 152 ASP B O   1 
ATOM   3402  C  CB  . ASP B 1 152 ? 33.829  -20.222 27.292  1.00 25.83  ? 152 ASP B CB  1 
ATOM   3403  C  CG  . ASP B 1 152 ? 33.602  -21.626 26.757  1.00 34.51  ? 152 ASP B CG  1 
ATOM   3404  O  OD1 . ASP B 1 152 ? 33.607  -21.764 25.534  1.00 35.52  ? 152 ASP B OD1 1 
ATOM   3405  O  OD2 . ASP B 1 152 ? 33.369  -22.583 27.586  1.00 39.67  ? 152 ASP B OD2 1 
ATOM   3406  N  N   . GLY B 1 153 ? 35.184  -19.155 24.193  1.00 24.99  ? 153 GLY B N   1 
ATOM   3407  C  CA  . GLY B 1 153 ? 34.873  -18.656 22.860  1.00 27.47  ? 153 GLY B CA  1 
ATOM   3408  C  C   . GLY B 1 153 ? 36.033  -17.927 22.156  1.00 25.36  ? 153 GLY B C   1 
ATOM   3409  O  O   . GLY B 1 153 ? 35.972  -17.733 20.964  1.00 26.54  ? 153 GLY B O   1 
ATOM   3410  N  N   . THR B 1 154 ? 37.103  -17.600 22.878  1.00 28.30  ? 154 THR B N   1 
ATOM   3411  C  CA  . THR B 1 154 ? 38.153  -16.671 22.480  1.00 29.42  ? 154 THR B CA  1 
ATOM   3412  C  C   . THR B 1 154 ? 38.805  -17.055 21.160  1.00 27.54  ? 154 THR B C   1 
ATOM   3413  O  O   . THR B 1 154 ? 39.019  -16.219 20.305  1.00 25.28  ? 154 THR B O   1 
ATOM   3414  C  CB  . THR B 1 154 ? 39.223  -16.673 23.567  1.00 31.41  ? 154 THR B CB  1 
ATOM   3415  O  OG1 . THR B 1 154 ? 38.595  -16.489 24.823  1.00 30.40  ? 154 THR B OG1 1 
ATOM   3416  C  CG2 . THR B 1 154 ? 40.228  -15.571 23.322  1.00 35.86  ? 154 THR B CG2 1 
ATOM   3417  N  N   . GLU B 1 155 ? 39.182  -18.322 21.025  1.00 28.30  ? 155 GLU B N   1 
ATOM   3418  C  CA  . GLU B 1 155 ? 39.912  -18.760 19.841  1.00 29.70  ? 155 GLU B CA  1 
ATOM   3419  C  C   . GLU B 1 155 ? 38.956  -19.325 18.788  1.00 31.81  ? 155 GLU B C   1 
ATOM   3420  O  O   . GLU B 1 155 ? 39.407  -19.944 17.843  1.00 37.99  ? 155 GLU B O   1 
ATOM   3421  C  CB  . GLU B 1 155 ? 41.048  -19.747 20.149  1.00 31.59  ? 155 GLU B CB  1 
ATOM   3422  C  CG  . GLU B 1 155 ? 42.198  -19.116 20.934  1.00 34.54  ? 155 GLU B CG  1 
ATOM   3423  C  CD  . GLU B 1 155 ? 42.957  -17.981 20.239  1.00 35.05  ? 155 GLU B CD  1 
ATOM   3424  O  OE1 . GLU B 1 155 ? 43.303  -18.328 19.102  1.00 30.86  ? 155 GLU B OE1 1 
ATOM   3425  O  OE2 . GLU B 1 155 ? 43.215  -16.839 20.739  1.00 33.84  ? 155 GLU B OE2 1 
ATOM   3426  N  N   . ASN B 1 156 ? 37.644  -19.095 18.849  1.00 29.24  ? 156 ASN B N   1 
ATOM   3427  C  CA  . ASN B 1 156 ? 36.810  -19.490 17.725  1.00 29.04  ? 156 ASN B CA  1 
ATOM   3428  C  C   . ASN B 1 156 ? 37.224  -18.742 16.456  1.00 33.93  ? 156 ASN B C   1 
ATOM   3429  O  O   . ASN B 1 156 ? 37.530  -17.560 16.515  1.00 33.94  ? 156 ASN B O   1 
ATOM   3430  C  CB  . ASN B 1 156 ? 35.343  -19.141 17.915  1.00 27.69  ? 156 ASN B CB  1 
ATOM   3431  C  CG  . ASN B 1 156 ? 34.587  -20.243 18.601  1.00 28.45  ? 156 ASN B CG  1 
ATOM   3432  O  OD1 . ASN B 1 156 ? 34.837  -21.430 18.371  1.00 29.83  ? 156 ASN B OD1 1 
ATOM   3433  N  ND2 . ASN B 1 156 ? 33.657  -19.872 19.451  1.00 28.02  ? 156 ASN B ND2 1 
ATOM   3434  N  N   . PRO B 1 157 ? 37.178  -19.364 15.257  1.00 33.17  ? 157 PRO B N   1 
ATOM   3435  C  CA  . PRO B 1 157 ? 37.444  -18.641 14.018  1.00 32.55  ? 157 PRO B CA  1 
ATOM   3436  C  C   . PRO B 1 157 ? 36.353  -17.618 13.744  1.00 35.05  ? 157 PRO B C   1 
ATOM   3437  O  O   . PRO B 1 157 ? 35.273  -17.741 14.303  1.00 36.94  ? 157 PRO B O   1 
ATOM   3438  C  CB  . PRO B 1 157 ? 37.495  -19.749 12.999  1.00 31.65  ? 157 PRO B CB  1 
ATOM   3439  C  CG  . PRO B 1 157 ? 36.604  -20.805 13.559  1.00 32.22  ? 157 PRO B CG  1 
ATOM   3440  C  CD  . PRO B 1 157 ? 36.831  -20.774 15.043  1.00 35.14  ? 157 PRO B CD  1 
ATOM   3441  N  N   . THR B 1 158 ? 36.668  -16.593 12.940  1.00 39.22  ? 158 THR B N   1 
ATOM   3442  C  CA  . THR B 1 158 ? 35.669  -15.606 12.533  1.00 44.47  ? 158 THR B CA  1 
ATOM   3443  C  C   . THR B 1 158 ? 35.763  -15.314 11.035  1.00 44.44  ? 158 THR B C   1 
ATOM   3444  O  O   . THR B 1 158 ? 36.753  -15.650 10.394  1.00 39.33  ? 158 THR B O   1 
ATOM   3445  C  CB  . THR B 1 158 ? 35.798  -14.308 13.331  1.00 38.59  ? 158 THR B CB  1 
ATOM   3446  O  OG1 . THR B 1 158 ? 37.135  -13.925 13.065  1.00 33.59  ? 158 THR B OG1 1 
ATOM   3447  C  CG2 . THR B 1 158 ? 35.535  -14.477 14.817  1.00 39.32  ? 158 THR B CG2 1 
ATOM   3448  N  N   . GLY B 1 159 ? 34.690  -14.701 10.502  1.00 48.60  ? 159 GLY B N   1 
ATOM   3449  C  CA  . GLY B 1 159 ? 34.626  -14.284 9.110   1.00 44.76  ? 159 GLY B CA  1 
ATOM   3450  C  C   . GLY B 1 159 ? 34.939  -15.437 8.161   1.00 45.69  ? 159 GLY B C   1 
ATOM   3451  O  O   . GLY B 1 159 ? 34.327  -16.489 8.260   1.00 46.00  ? 159 GLY B O   1 
ATOM   3452  N  N   . ALA B 1 160 ? 35.901  -15.227 7.260   1.00 45.50  ? 160 ALA B N   1 
ATOM   3453  C  CA  . ALA B 1 160 ? 36.139  -16.141 6.158   1.00 49.77  ? 160 ALA B CA  1 
ATOM   3454  C  C   . ALA B 1 160 ? 36.755  -17.423 6.691   1.00 46.49  ? 160 ALA B C   1 
ATOM   3455  O  O   . ALA B 1 160 ? 36.490  -18.489 6.151   1.00 43.65  ? 160 ALA B O   1 
ATOM   3456  C  CB  . ALA B 1 160 ? 37.026  -15.495 5.111   1.00 55.71  ? 160 ALA B CB  1 
ATOM   3457  N  N   . ALA B 1 161 ? 37.555  -17.317 7.764   1.00 48.41  ? 161 ALA B N   1 
ATOM   3458  C  CA  . ALA B 1 161 ? 38.178  -18.499 8.355   1.00 49.92  ? 161 ALA B CA  1 
ATOM   3459  C  C   . ALA B 1 161 ? 37.086  -19.445 8.868   1.00 51.44  ? 161 ALA B C   1 
ATOM   3460  O  O   . ALA B 1 161 ? 37.195  -20.669 8.758   1.00 46.80  ? 161 ALA B O   1 
ATOM   3461  C  CB  . ALA B 1 161 ? 39.157  -18.119 9.459   1.00 46.73  ? 161 ALA B CB  1 
ATOM   3462  N  N   . ALA B 1 162 ? 36.015  -18.862 9.425   1.00 47.51  ? 162 ALA B N   1 
ATOM   3463  C  CA  . ALA B 1 162 ? 34.920  -19.643 9.977   1.00 39.68  ? 162 ALA B CA  1 
ATOM   3464  C  C   . ALA B 1 162 ? 34.121  -20.296 8.847   1.00 35.36  ? 162 ALA B C   1 
ATOM   3465  O  O   . ALA B 1 162 ? 33.829  -21.483 8.927   1.00 32.34  ? 162 ALA B O   1 
ATOM   3466  C  CB  . ALA B 1 162 ? 34.087  -18.757 10.887  1.00 37.04  ? 162 ALA B CB  1 
ATOM   3467  N  N   . ARG B 1 163 ? 33.788  -19.530 7.799   1.00 37.18  ? 163 ARG B N   1 
ATOM   3468  C  CA  . ARG B 1 163 ? 33.146  -20.068 6.597   1.00 44.16  ? 163 ARG B CA  1 
ATOM   3469  C  C   . ARG B 1 163 ? 33.946  -21.284 6.120   1.00 34.67  ? 163 ARG B C   1 
ATOM   3470  O  O   . ARG B 1 163 ? 33.359  -22.335 5.950   1.00 33.09  ? 163 ARG B O   1 
ATOM   3471  C  CB  . ARG B 1 163 ? 32.886  -19.008 5.503   1.00 47.56  ? 163 ARG B CB  1 
ATOM   3472  C  CG  . ARG B 1 163 ? 31.783  -18.000 5.844   1.00 54.25  ? 163 ARG B CG  1 
ATOM   3473  C  CD  . ARG B 1 163 ? 31.666  -16.731 4.990   1.00 57.36  ? 163 ARG B CD  1 
ATOM   3474  N  NE  . ARG B 1 163 ? 31.451  -17.225 3.626   1.00 62.00  ? 163 ARG B NE  1 
ATOM   3475  N  N   . ARG B 1 164 ? 35.278  -21.163 6.017   1.00 33.09  ? 164 ARG B N   1 
ATOM   3476  C  CA  . ARG B 1 164 ? 36.147  -22.235 5.540   1.00 40.43  ? 164 ARG B CA  1 
ATOM   3477  C  C   . ARG B 1 164 ? 36.096  -23.425 6.520   1.00 44.15  ? 164 ARG B C   1 
ATOM   3478  O  O   . ARG B 1 164 ? 36.168  -24.582 6.107   1.00 45.69  ? 164 ARG B O   1 
ATOM   3479  C  CB  . ARG B 1 164 ? 37.583  -21.784 5.136   1.00 34.18  ? 164 ARG B CB  1 
ATOM   3480  N  N   . ALA B 1 165 ? 35.959  -23.181 7.823   1.00 43.98  ? 165 ALA B N   1 
ATOM   3481  C  CA  . ALA B 1 165 ? 36.072  -24.276 8.776   1.00 43.36  ? 165 ALA B CA  1 
ATOM   3482  C  C   . ALA B 1 165 ? 34.760  -25.045 8.948   1.00 40.35  ? 165 ALA B C   1 
ATOM   3483  O  O   . ALA B 1 165 ? 34.758  -26.190 9.380   1.00 35.29  ? 165 ALA B O   1 
ATOM   3484  C  CB  . ALA B 1 165 ? 36.534  -23.736 10.115  1.00 44.82  ? 165 ALA B CB  1 
ATOM   3485  N  N   . VAL B 1 166 ? 33.622  -24.403 8.683   1.00 38.97  ? 166 VAL B N   1 
ATOM   3486  C  CA  . VAL B 1 166 ? 32.358  -24.913 9.196   1.00 38.53  ? 166 VAL B CA  1 
ATOM   3487  C  C   . VAL B 1 166 ? 31.456  -25.410 8.063   1.00 38.72  ? 166 VAL B C   1 
ATOM   3488  O  O   . VAL B 1 166 ? 30.653  -26.315 8.285   1.00 46.95  ? 166 VAL B O   1 
ATOM   3489  C  CB  . VAL B 1 166 ? 31.712  -23.740 9.968   1.00 41.68  ? 166 VAL B CB  1 
ATOM   3490  C  CG1 . VAL B 1 166 ? 30.196  -23.842 10.065  1.00 42.66  ? 166 VAL B CG1 1 
ATOM   3491  C  CG2 . VAL B 1 166 ? 32.294  -23.547 11.357  1.00 41.39  ? 166 VAL B CG2 1 
ATOM   3492  N  N   . LEU B 1 167 ? 31.536  -24.802 6.870   1.00 32.30  ? 167 LEU B N   1 
ATOM   3493  C  CA  . LEU B 1 167 ? 30.550  -25.066 5.836   1.00 31.98  ? 167 LEU B CA  1 
ATOM   3494  C  C   . LEU B 1 167 ? 31.067  -26.051 4.789   1.00 35.36  ? 167 LEU B C   1 
ATOM   3495  O  O   . LEU B 1 167 ? 32.177  -25.920 4.271   1.00 30.11  ? 167 LEU B O   1 
ATOM   3496  C  CB  . LEU B 1 167 ? 30.149  -23.745 5.196   1.00 33.91  ? 167 LEU B CB  1 
ATOM   3497  C  CG  . LEU B 1 167 ? 29.498  -22.757 6.156   1.00 35.20  ? 167 LEU B CG  1 
ATOM   3498  C  CD1 . LEU B 1 167 ? 29.334  -21.394 5.515   1.00 37.68  ? 167 LEU B CD1 1 
ATOM   3499  C  CD2 . LEU B 1 167 ? 28.208  -23.398 6.608   1.00 34.84  ? 167 LEU B CD2 1 
ATOM   3500  N  N   . VAL B 1 168 ? 30.211  -27.043 4.489   1.00 37.41  ? 168 VAL B N   1 
ATOM   3501  C  CA  . VAL B 1 168 ? 30.488  -28.040 3.478   1.00 36.60  ? 168 VAL B CA  1 
ATOM   3502  C  C   . VAL B 1 168 ? 30.620  -27.304 2.157   1.00 41.91  ? 168 VAL B C   1 
ATOM   3503  O  O   . VAL B 1 168 ? 29.836  -26.409 1.875   1.00 46.47  ? 168 VAL B O   1 
ATOM   3504  C  CB  . VAL B 1 168 ? 29.362  -29.089 3.446   1.00 37.59  ? 168 VAL B CB  1 
ATOM   3505  C  CG1 . VAL B 1 168 ? 29.483  -30.022 2.243   1.00 40.30  ? 168 VAL B CG1 1 
ATOM   3506  C  CG2 . VAL B 1 168 ? 29.297  -29.902 4.732   1.00 41.48  ? 168 VAL B CG2 1 
ATOM   3507  N  N   . GLY B 1 169 ? 31.620  -27.668 1.355   1.00 43.00  ? 169 GLY B N   1 
ATOM   3508  C  CA  . GLY B 1 169 ? 31.795  -27.050 0.049   1.00 45.12  ? 169 GLY B CA  1 
ATOM   3509  C  C   . GLY B 1 169 ? 31.759  -28.081 -1.078  1.00 46.73  ? 169 GLY B C   1 
ATOM   3510  O  O   . GLY B 1 169 ? 30.952  -29.027 -1.104  1.00 39.02  ? 169 GLY B O   1 
ATOM   3511  N  N   . ALA B 1 170 ? 32.696  -27.874 -2.004  1.00 58.03  ? 170 ALA B N   1 
ATOM   3512  C  CA  . ALA B 1 170 ? 32.808  -28.643 -3.233  1.00 54.64  ? 170 ALA B CA  1 
ATOM   3513  C  C   . ALA B 1 170 ? 33.161  -30.105 -2.950  1.00 50.78  ? 170 ALA B C   1 
ATOM   3514  O  O   . ALA B 1 170 ? 32.915  -30.943 -3.794  1.00 53.20  ? 170 ALA B O   1 
ATOM   3515  C  CB  . ALA B 1 170 ? 33.828  -27.958 -4.117  1.00 48.38  ? 170 ALA B CB  1 
ATOM   3516  N  N   . GLU B 1 171 ? 33.683  -30.441 -1.765  1.00 47.23  ? 171 GLU B N   1 
ATOM   3517  C  CA  . GLU B 1 171 ? 34.049  -31.820 -1.468  1.00 48.08  ? 171 GLU B CA  1 
ATOM   3518  C  C   . GLU B 1 171 ? 32.820  -32.720 -1.313  1.00 44.01  ? 171 GLU B C   1 
ATOM   3519  O  O   . GLU B 1 171 ? 32.960  -33.926 -1.252  1.00 47.31  ? 171 GLU B O   1 
ATOM   3520  C  CB  . GLU B 1 171 ? 35.008  -31.878 -0.272  1.00 45.80  ? 171 GLU B CB  1 
ATOM   3521  C  CG  . GLU B 1 171 ? 34.354  -31.750 1.102   1.00 44.87  ? 171 GLU B CG  1 
ATOM   3522  C  CD  . GLU B 1 171 ? 33.844  -30.397 1.561   1.00 49.07  ? 171 GLU B CD  1 
ATOM   3523  O  OE1 . GLU B 1 171 ? 34.005  -29.411 0.797   1.00 46.64  ? 171 GLU B OE1 1 
ATOM   3524  O  OE2 . GLU B 1 171 ? 33.281  -30.322 2.693   1.00 51.19  ? 171 GLU B OE2 1 
ATOM   3525  N  N   . ASP B 1 172 ? 31.619  -32.144 -1.207  1.00 48.41  ? 172 ASP B N   1 
ATOM   3526  C  CA  . ASP B 1 172 ? 30.375  -32.912 -1.124  1.00 53.99  ? 172 ASP B CA  1 
ATOM   3527  C  C   . ASP B 1 172 ? 29.259  -32.012 -1.643  1.00 51.82  ? 172 ASP B C   1 
ATOM   3528  O  O   . ASP B 1 172 ? 28.391  -31.558 -0.899  1.00 48.64  ? 172 ASP B O   1 
ATOM   3529  C  CB  . ASP B 1 172 ? 30.106  -33.441 0.284   1.00 55.21  ? 172 ASP B CB  1 
ATOM   3530  C  CG  . ASP B 1 172 ? 28.971  -34.452 0.418   1.00 53.63  ? 172 ASP B CG  1 
ATOM   3531  O  OD1 . ASP B 1 172 ? 28.475  -34.877 -0.628  1.00 56.79  ? 172 ASP B OD1 1 
ATOM   3532  O  OD2 . ASP B 1 172 ? 28.567  -34.794 1.564   1.00 55.50  ? 172 ASP B OD2 1 
ATOM   3533  N  N   . PRO B 1 173 ? 29.296  -31.698 -2.951  1.00 51.66  ? 173 PRO B N   1 
ATOM   3534  C  CA  . PRO B 1 173 ? 28.653  -30.481 -3.471  1.00 51.89  ? 173 PRO B CA  1 
ATOM   3535  C  C   . PRO B 1 173 ? 27.132  -30.491 -3.404  1.00 41.64  ? 173 PRO B C   1 
ATOM   3536  O  O   . PRO B 1 173 ? 26.511  -29.435 -3.412  1.00 40.69  ? 173 PRO B O   1 
ATOM   3537  C  CB  . PRO B 1 173 ? 29.187  -30.369 -4.901  1.00 53.32  ? 173 PRO B CB  1 
ATOM   3538  C  CG  . PRO B 1 173 ? 29.622  -31.797 -5.259  1.00 50.46  ? 173 PRO B CG  1 
ATOM   3539  C  CD  . PRO B 1 173 ? 30.021  -32.479 -3.962  1.00 50.34  ? 173 PRO B CD  1 
ATOM   3540  N  N   . ALA B 1 174 ? 26.548  -31.692 -3.353  1.00 38.36  ? 174 ALA B N   1 
ATOM   3541  C  CA  . ALA B 1 174 ? 25.118  -31.820 -3.161  1.00 44.67  ? 174 ALA B CA  1 
ATOM   3542  C  C   . ALA B 1 174 ? 24.659  -31.154 -1.869  1.00 43.37  ? 174 ALA B C   1 
ATOM   3543  O  O   . ALA B 1 174 ? 23.488  -30.826 -1.779  1.00 45.31  ? 174 ALA B O   1 
ATOM   3544  C  CB  . ALA B 1 174 ? 24.756  -33.285 -3.123  1.00 48.08  ? 174 ALA B CB  1 
ATOM   3545  N  N   . PHE B 1 175 ? 25.551  -31.052 -0.859  1.00 45.39  ? 175 PHE B N   1 
ATOM   3546  C  CA  . PHE B 1 175 ? 25.189  -30.652 0.498   1.00 45.21  ? 175 PHE B CA  1 
ATOM   3547  C  C   . PHE B 1 175 ? 25.964  -29.431 0.977   1.00 43.77  ? 175 PHE B C   1 
ATOM   3548  O  O   . PHE B 1 175 ? 25.927  -29.095 2.154   1.00 47.42  ? 175 PHE B O   1 
ATOM   3549  C  CB  . PHE B 1 175 ? 25.437  -31.847 1.405   1.00 41.33  ? 175 PHE B CB  1 
ATOM   3550  C  CG  . PHE B 1 175 ? 24.489  -32.999 1.113   1.00 42.60  ? 175 PHE B CG  1 
ATOM   3551  C  CD1 . PHE B 1 175 ? 23.140  -32.887 1.403   1.00 40.64  ? 175 PHE B CD1 1 
ATOM   3552  C  CD2 . PHE B 1 175 ? 24.972  -34.198 0.582   1.00 46.57  ? 175 PHE B CD2 1 
ATOM   3553  C  CE1 . PHE B 1 175 ? 22.287  -33.947 1.169   1.00 44.97  ? 175 PHE B CE1 1 
ATOM   3554  C  CE2 . PHE B 1 175 ? 24.100  -35.250 0.320   1.00 47.78  ? 175 PHE B CE2 1 
ATOM   3555  C  CZ  . PHE B 1 175 ? 22.763  -35.129 0.635   1.00 47.09  ? 175 PHE B CZ  1 
ATOM   3556  N  N   . ALA B 1 176 ? 26.622  -28.752 0.040   1.00 45.15  ? 176 ALA B N   1 
ATOM   3557  C  CA  . ALA B 1 176 ? 27.235  -27.458 0.270   1.00 43.22  ? 176 ALA B CA  1 
ATOM   3558  C  C   . ALA B 1 176 ? 26.260  -26.533 0.991   1.00 42.56  ? 176 ALA B C   1 
ATOM   3559  O  O   . ALA B 1 176 ? 25.093  -26.430 0.592   1.00 39.21  ? 176 ALA B O   1 
ATOM   3560  C  CB  . ALA B 1 176 ? 27.654  -26.855 -1.051  1.00 41.42  ? 176 ALA B CB  1 
ATOM   3561  N  N   . GLY B 1 177 ? 26.792  -25.862 2.031   1.00 41.52  ? 177 GLY B N   1 
ATOM   3562  C  CA  . GLY B 1 177 ? 26.063  -24.905 2.861   1.00 47.12  ? 177 GLY B CA  1 
ATOM   3563  C  C   . GLY B 1 177 ? 25.663  -25.527 4.202   1.00 48.09  ? 177 GLY B C   1 
ATOM   3564  O  O   . GLY B 1 177 ? 25.114  -24.874 5.113   1.00 50.29  ? 177 GLY B O   1 
ATOM   3565  N  N   . GLY B 1 178 ? 25.895  -26.841 4.269   1.00 42.88  ? 178 GLY B N   1 
ATOM   3566  C  CA  . GLY B 1 178 ? 25.631  -27.607 5.462   1.00 35.16  ? 178 GLY B CA  1 
ATOM   3567  C  C   . GLY B 1 178 ? 26.826  -27.568 6.406   1.00 31.55  ? 178 GLY B C   1 
ATOM   3568  O  O   . GLY B 1 178 ? 27.870  -26.984 6.115   1.00 28.56  ? 178 GLY B O   1 
ATOM   3569  N  N   . SER B 1 179 ? 26.623  -28.226 7.542   1.00 28.57  ? 179 SER B N   1 
ATOM   3570  C  CA  . SER B 1 179 ? 27.633  -28.334 8.565   1.00 27.12  ? 179 SER B CA  1 
ATOM   3571  C  C   . SER B 1 179 ? 27.294  -29.548 9.419   1.00 29.43  ? 179 SER B C   1 
ATOM   3572  O  O   . SER B 1 179 ? 26.206  -30.145 9.290   1.00 27.99  ? 179 SER B O   1 
ATOM   3573  C  CB  . SER B 1 179 ? 27.738  -27.061 9.373   1.00 26.68  ? 179 SER B CB  1 
ATOM   3574  O  OG  . SER B 1 179 ? 28.931  -27.039 10.157  1.00 27.19  ? 179 SER B OG  1 
ATOM   3575  N  N   . TYR B 1 180 ? 28.280  -29.938 10.239  1.00 32.59  ? 180 TYR B N   1 
ATOM   3576  C  CA  . TYR B 1 180 ? 28.122  -31.071 11.135  1.00 34.22  ? 180 TYR B CA  1 
ATOM   3577  C  C   . TYR B 1 180 ? 28.234  -30.560 12.571  1.00 35.24  ? 180 TYR B C   1 
ATOM   3578  O  O   . TYR B 1 180 ? 29.243  -29.928 12.942  1.00 41.81  ? 180 TYR B O   1 
ATOM   3579  C  CB  . TYR B 1 180 ? 29.178  -32.138 10.826  1.00 34.55  ? 180 TYR B CB  1 
ATOM   3580  C  CG  . TYR B 1 180 ? 29.039  -32.818 9.476   1.00 30.47  ? 180 TYR B CG  1 
ATOM   3581  C  CD1 . TYR B 1 180 ? 29.640  -32.288 8.348   1.00 33.50  ? 180 TYR B CD1 1 
ATOM   3582  C  CD2 . TYR B 1 180 ? 28.307  -33.984 9.335   1.00 33.27  ? 180 TYR B CD2 1 
ATOM   3583  C  CE1 . TYR B 1 180 ? 29.482  -32.886 7.105   1.00 36.65  ? 180 TYR B CE1 1 
ATOM   3584  C  CE2 . TYR B 1 180 ? 28.141  -34.583 8.100   1.00 33.87  ? 180 TYR B CE2 1 
ATOM   3585  C  CZ  . TYR B 1 180 ? 28.729  -34.038 6.975   1.00 33.46  ? 180 TYR B CZ  1 
ATOM   3586  O  OH  . TYR B 1 180 ? 28.582  -34.655 5.759   1.00 28.34  ? 180 TYR B OH  1 
ATOM   3587  N  N   . ALA B 1 181 ? 27.210  -30.895 13.365  1.00 28.36  ? 181 ALA B N   1 
ATOM   3588  C  CA  . ALA B 1 181 ? 27.148  -30.473 14.752  1.00 31.18  ? 181 ALA B CA  1 
ATOM   3589  C  C   . ALA B 1 181 ? 27.314  -31.681 15.670  1.00 32.17  ? 181 ALA B C   1 
ATOM   3590  O  O   . ALA B 1 181 ? 26.606  -32.681 15.515  1.00 28.42  ? 181 ALA B O   1 
ATOM   3591  C  CB  . ALA B 1 181 ? 25.832  -29.779 15.020  1.00 29.39  ? 181 ALA B CB  1 
ATOM   3592  N  N   . VAL B 1 182 ? 28.229  -31.555 16.636  1.00 32.63  ? 182 VAL B N   1 
ATOM   3593  C  CA  . VAL B 1 182 ? 28.353  -32.511 17.727  1.00 35.63  ? 182 VAL B CA  1 
ATOM   3594  C  C   . VAL B 1 182 ? 27.909  -31.828 19.007  1.00 32.01  ? 182 VAL B C   1 
ATOM   3595  O  O   . VAL B 1 182 ? 28.362  -30.720 19.278  1.00 29.42  ? 182 VAL B O   1 
ATOM   3596  C  CB  . VAL B 1 182 ? 29.808  -33.010 17.860  1.00 39.17  ? 182 VAL B CB  1 
ATOM   3597  C  CG1 . VAL B 1 182 ? 29.964  -33.940 19.058  1.00 37.90  ? 182 VAL B CG1 1 
ATOM   3598  C  CG2 . VAL B 1 182 ? 30.293  -33.684 16.574  1.00 40.18  ? 182 VAL B CG2 1 
ATOM   3599  N  N   . VAL B 1 183 ? 27.057  -32.515 19.783  1.00 29.27  ? 183 VAL B N   1 
ATOM   3600  C  CA  . VAL B 1 183 ? 26.615  -32.014 21.073  1.00 28.02  ? 183 VAL B CA  1 
ATOM   3601  C  C   . VAL B 1 183 ? 27.047  -32.997 22.156  1.00 29.43  ? 183 VAL B C   1 
ATOM   3602  O  O   . VAL B 1 183 ? 27.030  -34.204 21.959  1.00 32.34  ? 183 VAL B O   1 
ATOM   3603  C  CB  . VAL B 1 183 ? 25.098  -31.726 21.143  1.00 25.69  ? 183 VAL B CB  1 
ATOM   3604  C  CG1 . VAL B 1 183 ? 24.683  -30.658 20.130  1.00 25.09  ? 183 VAL B CG1 1 
ATOM   3605  C  CG2 . VAL B 1 183 ? 24.264  -32.975 20.963  1.00 25.62  ? 183 VAL B CG2 1 
ATOM   3606  N  N   . GLN B 1 184 ? 27.448  -32.447 23.297  1.00 28.69  ? 184 GLN B N   1 
ATOM   3607  C  CA  . GLN B 1 184 ? 27.603  -33.195 24.532  1.00 30.41  ? 184 GLN B CA  1 
ATOM   3608  C  C   . GLN B 1 184 ? 27.138  -32.323 25.704  1.00 31.91  ? 184 GLN B C   1 
ATOM   3609  O  O   . GLN B 1 184 ? 27.568  -31.179 25.857  1.00 28.65  ? 184 GLN B O   1 
ATOM   3610  C  CB  . GLN B 1 184 ? 29.069  -33.529 24.807  1.00 28.79  ? 184 GLN B CB  1 
ATOM   3611  C  CG  . GLN B 1 184 ? 29.675  -34.516 23.835  1.00 30.75  ? 184 GLN B CG  1 
ATOM   3612  C  CD  . GLN B 1 184 ? 31.118  -34.788 24.202  1.00 35.72  ? 184 GLN B CD  1 
ATOM   3613  O  OE1 . GLN B 1 184 ? 31.964  -33.888 24.147  1.00 29.44  ? 184 GLN B OE1 1 
ATOM   3614  N  NE2 . GLN B 1 184 ? 31.380  -36.009 24.654  1.00 38.61  ? 184 GLN B NE2 1 
ATOM   3615  N  N   . LYS B 1 185 ? 26.307  -32.894 26.572  1.00 30.48  ? 185 LYS B N   1 
ATOM   3616  C  CA  . LYS B 1 185 ? 25.987  -32.224 27.809  1.00 30.04  ? 185 LYS B CA  1 
ATOM   3617  C  C   . LYS B 1 185 ? 26.980  -32.668 28.877  1.00 29.72  ? 185 LYS B C   1 
ATOM   3618  O  O   . LYS B 1 185 ? 27.107  -33.855 29.126  1.00 28.70  ? 185 LYS B O   1 
ATOM   3619  C  CB  . LYS B 1 185 ? 24.546  -32.571 28.173  1.00 29.80  ? 185 LYS B CB  1 
ATOM   3620  C  CG  . LYS B 1 185 ? 24.174  -32.007 29.520  1.00 29.46  ? 185 LYS B CG  1 
ATOM   3621  C  CD  . LYS B 1 185 ? 22.678  -31.769 29.701  1.00 28.64  ? 185 LYS B CD  1 
ATOM   3622  C  CE  . LYS B 1 185 ? 22.032  -33.096 29.808  1.00 31.89  ? 185 LYS B CE  1 
ATOM   3623  N  NZ  . LYS B 1 185 ? 20.610  -32.938 30.055  1.00 35.81  ? 185 LYS B NZ  1 
ATOM   3624  N  N   . TYR B 1 186 ? 27.676  -31.714 29.502  1.00 28.05  ? 186 TYR B N   1 
ATOM   3625  C  CA  . TYR B 1 186 ? 28.638  -31.993 30.563  1.00 26.36  ? 186 TYR B CA  1 
ATOM   3626  C  C   . TYR B 1 186 ? 28.106  -31.505 31.902  1.00 26.35  ? 186 TYR B C   1 
ATOM   3627  O  O   . TYR B 1 186 ? 27.541  -30.421 31.979  1.00 27.31  ? 186 TYR B O   1 
ATOM   3628  C  CB  . TYR B 1 186 ? 29.988  -31.307 30.336  1.00 23.88  ? 186 TYR B CB  1 
ATOM   3629  C  CG  . TYR B 1 186 ? 30.860  -31.956 29.280  1.00 24.23  ? 186 TYR B CG  1 
ATOM   3630  C  CD1 . TYR B 1 186 ? 31.710  -32.986 29.607  1.00 26.90  ? 186 TYR B CD1 1 
ATOM   3631  C  CD2 . TYR B 1 186 ? 30.829  -31.536 27.958  1.00 25.51  ? 186 TYR B CD2 1 
ATOM   3632  C  CE1 . TYR B 1 186 ? 32.512  -33.592 28.656  1.00 28.41  ? 186 TYR B CE1 1 
ATOM   3633  C  CE2 . TYR B 1 186 ? 31.632  -32.118 26.991  1.00 26.46  ? 186 TYR B CE2 1 
ATOM   3634  C  CZ  . TYR B 1 186 ? 32.466  -33.166 27.345  1.00 28.95  ? 186 TYR B CZ  1 
ATOM   3635  O  OH  . TYR B 1 186 ? 33.266  -33.769 26.415  1.00 27.17  ? 186 TYR B OH  1 
ATOM   3636  N  N   . LEU B 1 187 ? 28.331  -32.307 32.947  1.00 30.05  ? 187 LEU B N   1 
ATOM   3637  C  CA  . LEU B 1 187 ? 28.121  -31.865 34.314  1.00 28.30  ? 187 LEU B CA  1 
ATOM   3638  C  C   . LEU B 1 187 ? 29.471  -31.747 35.000  1.00 29.64  ? 187 LEU B C   1 
ATOM   3639  O  O   . LEU B 1 187 ? 30.351  -32.581 34.817  1.00 28.95  ? 187 LEU B O   1 
ATOM   3640  C  CB  . LEU B 1 187 ? 27.222  -32.869 35.027  1.00 28.94  ? 187 LEU B CB  1 
ATOM   3641  C  CG  . LEU B 1 187 ? 25.784  -32.931 34.506  1.00 29.17  ? 187 LEU B CG  1 
ATOM   3642  C  CD1 . LEU B 1 187 ? 25.031  -34.006 35.217  1.00 27.31  ? 187 LEU B CD1 1 
ATOM   3643  C  CD2 . LEU B 1 187 ? 25.074  -31.582 34.713  1.00 32.80  ? 187 LEU B CD2 1 
ATOM   3644  N  N   . HIS B 1 188 ? 29.617  -30.716 35.822  1.00 29.60  ? 188 HIS B N   1 
ATOM   3645  C  CA  . HIS B 1 188 ? 30.891  -30.441 36.440  1.00 31.20  ? 188 HIS B CA  1 
ATOM   3646  C  C   . HIS B 1 188 ? 30.803  -30.760 37.929  1.00 29.21  ? 188 HIS B C   1 
ATOM   3647  O  O   . HIS B 1 188 ? 29.748  -30.616 38.510  1.00 27.91  ? 188 HIS B O   1 
ATOM   3648  C  CB  . HIS B 1 188 ? 31.261  -28.961 36.306  1.00 30.54  ? 188 HIS B CB  1 
ATOM   3649  C  CG  . HIS B 1 188 ? 31.468  -28.508 34.925  1.00 29.11  ? 188 HIS B CG  1 
ATOM   3650  N  ND1 . HIS B 1 188 ? 32.575  -28.897 34.203  1.00 29.04  ? 188 HIS B ND1 1 
ATOM   3651  C  CD2 . HIS B 1 188 ? 30.709  -27.728 34.120  1.00 31.75  ? 188 HIS B CD2 1 
ATOM   3652  C  CE1 . HIS B 1 188 ? 32.476  -28.354 32.988  1.00 33.70  ? 188 HIS B CE1 1 
ATOM   3653  N  NE2 . HIS B 1 188 ? 31.348  -27.646 32.913  1.00 30.87  ? 188 HIS B NE2 1 
ATOM   3654  N  N   . ASP B 1 189 ? 31.931  -31.195 38.494  1.00 29.33  ? 189 ASP B N   1 
ATOM   3655  C  CA  . ASP B 1 189 ? 32.110  -31.318 39.922  1.00 30.22  ? 189 ASP B CA  1 
ATOM   3656  C  C   . ASP B 1 189 ? 32.715  -30.001 40.394  1.00 30.22  ? 189 ASP B C   1 
ATOM   3657  O  O   . ASP B 1 189 ? 33.942  -29.848 40.425  1.00 27.54  ? 189 ASP B O   1 
ATOM   3658  C  CB  . ASP B 1 189 ? 32.973  -32.520 40.248  1.00 27.70  ? 189 ASP B CB  1 
ATOM   3659  C  CG  . ASP B 1 189 ? 33.243  -32.713 41.720  1.00 30.31  ? 189 ASP B CG  1 
ATOM   3660  O  OD1 . ASP B 1 189 ? 32.825  -31.853 42.530  1.00 33.17  ? 189 ASP B OD1 1 
ATOM   3661  O  OD2 . ASP B 1 189 ? 33.887  -33.702 42.022  1.00 34.03  ? 189 ASP B OD2 1 
ATOM   3662  N  N   . ILE B 1 190 ? 31.836  -29.055 40.727  1.00 27.50  ? 190 ILE B N   1 
ATOM   3663  C  CA  . ILE B 1 190 ? 32.282  -27.716 41.044  1.00 26.58  ? 190 ILE B CA  1 
ATOM   3664  C  C   . ILE B 1 190 ? 33.075  -27.680 42.342  1.00 27.03  ? 190 ILE B C   1 
ATOM   3665  O  O   . ILE B 1 190 ? 33.964  -26.855 42.484  1.00 28.19  ? 190 ILE B O   1 
ATOM   3666  C  CB  . ILE B 1 190 ? 31.092  -26.748 41.087  1.00 28.97  ? 190 ILE B CB  1 
ATOM   3667  C  CG1 . ILE B 1 190 ? 30.582  -26.418 39.676  1.00 28.56  ? 190 ILE B CG1 1 
ATOM   3668  C  CG2 . ILE B 1 190 ? 31.495  -25.461 41.792  1.00 30.22  ? 190 ILE B CG2 1 
ATOM   3669  C  CD1 . ILE B 1 190 ? 31.618  -25.741 38.762  1.00 25.09  ? 190 ILE B CD1 1 
ATOM   3670  N  N   . ASP B 1 191 ? 32.736  -28.534 43.304  1.00 29.27  ? 191 ASP B N   1 
ATOM   3671  C  CA  . ASP B 1 191 ? 33.416  -28.536 44.589  1.00 30.95  ? 191 ASP B CA  1 
ATOM   3672  C  C   . ASP B 1 191 ? 34.881  -28.875 44.371  1.00 28.16  ? 191 ASP B C   1 
ATOM   3673  O  O   . ASP B 1 191 ? 35.764  -28.203 44.878  1.00 25.85  ? 191 ASP B O   1 
ATOM   3674  C  CB  . ASP B 1 191 ? 32.794  -29.557 45.522  1.00 39.00  ? 191 ASP B CB  1 
ATOM   3675  C  CG  . ASP B 1 191 ? 31.770  -28.988 46.487  1.00 47.12  ? 191 ASP B CG  1 
ATOM   3676  O  OD1 . ASP B 1 191 ? 30.958  -28.180 46.038  1.00 42.14  ? 191 ASP B OD1 1 
ATOM   3677  O  OD2 . ASP B 1 191 ? 31.840  -29.344 47.692  1.00 73.53  ? 191 ASP B OD2 1 
ATOM   3678  N  N   . ALA B 1 192 ? 35.127  -29.935 43.601  1.00 26.35  ? 192 ALA B N   1 
ATOM   3679  C  CA  . ALA B 1 192 ? 36.495  -30.307 43.275  1.00 26.05  ? 192 ALA B CA  1 
ATOM   3680  C  C   . ALA B 1 192 ? 37.207  -29.147 42.579  1.00 29.48  ? 192 ALA B C   1 
ATOM   3681  O  O   . ALA B 1 192 ? 38.340  -28.840 42.894  1.00 31.05  ? 192 ALA B O   1 
ATOM   3682  C  CB  . ALA B 1 192 ? 36.515  -31.528 42.413  1.00 24.03  ? 192 ALA B CB  1 
ATOM   3683  N  N   . TRP B 1 193 ? 36.540  -28.544 41.589  1.00 32.56  ? 193 TRP B N   1 
ATOM   3684  C  CA  . TRP B 1 193 ? 37.119  -27.494 40.760  1.00 31.16  ? 193 TRP B CA  1 
ATOM   3685  C  C   . TRP B 1 193 ? 37.562  -26.304 41.612  1.00 28.19  ? 193 TRP B C   1 
ATOM   3686  O  O   . TRP B 1 193 ? 38.683  -25.814 41.466  1.00 27.64  ? 193 TRP B O   1 
ATOM   3687  C  CB  . TRP B 1 193 ? 36.109  -27.053 39.686  1.00 31.13  ? 193 TRP B CB  1 
ATOM   3688  C  CG  . TRP B 1 193 ? 36.621  -25.957 38.778  1.00 28.43  ? 193 TRP B CG  1 
ATOM   3689  C  CD1 . TRP B 1 193 ? 36.189  -24.667 38.701  1.00 27.76  ? 193 TRP B CD1 1 
ATOM   3690  C  CD2 . TRP B 1 193 ? 37.683  -26.073 37.811  1.00 25.48  ? 193 TRP B CD2 1 
ATOM   3691  N  NE1 . TRP B 1 193 ? 36.891  -23.988 37.740  1.00 26.40  ? 193 TRP B NE1 1 
ATOM   3692  C  CE2 . TRP B 1 193 ? 37.824  -24.817 37.195  1.00 26.38  ? 193 TRP B CE2 1 
ATOM   3693  C  CE3 . TRP B 1 193 ? 38.516  -27.119 37.418  1.00 26.82  ? 193 TRP B CE3 1 
ATOM   3694  C  CZ2 . TRP B 1 193 ? 38.766  -24.572 36.209  1.00 28.71  ? 193 TRP B CZ2 1 
ATOM   3695  C  CZ3 . TRP B 1 193 ? 39.491  -26.862 36.481  1.00 30.64  ? 193 TRP B CZ3 1 
ATOM   3696  C  CH2 . TRP B 1 193 ? 39.611  -25.604 35.879  1.00 31.51  ? 193 TRP B CH2 1 
ATOM   3697  N  N   . GLU B 1 194 ? 36.688  -25.902 42.521  1.00 26.78  ? 194 GLU B N   1 
ATOM   3698  C  CA  . GLU B 1 194 ? 36.907  -24.731 43.337  1.00 32.44  ? 194 GLU B CA  1 
ATOM   3699  C  C   . GLU B 1 194 ? 37.954  -25.039 44.401  1.00 34.20  ? 194 GLU B C   1 
ATOM   3700  O  O   . GLU B 1 194 ? 38.445  -24.138 45.061  1.00 33.59  ? 194 GLU B O   1 
ATOM   3701  C  CB  . GLU B 1 194 ? 35.595  -24.253 43.944  1.00 40.23  ? 194 GLU B CB  1 
ATOM   3702  C  CG  . GLU B 1 194 ? 35.354  -22.764 43.682  1.00 51.24  ? 194 GLU B CG  1 
ATOM   3703  C  CD  . GLU B 1 194 ? 34.004  -22.583 42.990  1.00 55.73  ? 194 GLU B CD  1 
ATOM   3704  O  OE1 . GLU B 1 194 ? 32.901  -22.743 43.572  1.00 59.55  ? 194 GLU B OE1 1 
ATOM   3705  O  OE2 . GLU B 1 194 ? 34.073  -22.313 41.787  1.00 57.85  ? 194 GLU B OE2 1 
ATOM   3706  N  N   . GLY B 1 195 ? 38.360  -26.302 44.541  1.00 32.33  ? 195 GLY B N   1 
ATOM   3707  C  CA  . GLY B 1 195 ? 39.444  -26.589 45.459  1.00 30.37  ? 195 GLY B CA  1 
ATOM   3708  C  C   . GLY B 1 195 ? 40.829  -26.376 44.854  1.00 33.29  ? 195 GLY B C   1 
ATOM   3709  O  O   . GLY B 1 195 ? 41.807  -26.433 45.581  1.00 43.65  ? 195 GLY B O   1 
ATOM   3710  N  N   . LEU B 1 196 ? 40.941  -26.182 43.537  1.00 29.27  ? 196 LEU B N   1 
ATOM   3711  C  CA  . LEU B 1 196 ? 42.231  -25.866 42.941  1.00 29.58  ? 196 LEU B CA  1 
ATOM   3712  C  C   . LEU B 1 196 ? 42.536  -24.394 43.145  1.00 29.76  ? 196 LEU B C   1 
ATOM   3713  O  O   . LEU B 1 196 ? 41.624  -23.589 43.183  1.00 29.55  ? 196 LEU B O   1 
ATOM   3714  C  CB  . LEU B 1 196 ? 42.189  -26.163 41.454  1.00 32.99  ? 196 LEU B CB  1 
ATOM   3715  C  CG  . LEU B 1 196 ? 42.487  -27.589 41.021  1.00 35.71  ? 196 LEU B CG  1 
ATOM   3716  C  CD1 . LEU B 1 196 ? 41.630  -28.547 41.783  1.00 39.90  ? 196 LEU B CD1 1 
ATOM   3717  C  CD2 . LEU B 1 196 ? 42.246  -27.664 39.556  1.00 37.71  ? 196 LEU B CD2 1 
ATOM   3718  N  N   . SER B 1 197 ? 43.811  -24.041 43.252  1.00 30.53  ? 197 SER B N   1 
ATOM   3719  C  CA  . SER B 1 197 ? 44.193  -22.645 43.159  1.00 30.83  ? 197 SER B CA  1 
ATOM   3720  C  C   . SER B 1 197 ? 43.920  -22.169 41.735  1.00 33.53  ? 197 SER B C   1 
ATOM   3721  O  O   . SER B 1 197 ? 43.759  -22.959 40.810  1.00 30.07  ? 197 SER B O   1 
ATOM   3722  C  CB  . SER B 1 197 ? 45.620  -22.471 43.475  1.00 31.91  ? 197 SER B CB  1 
ATOM   3723  O  OG  . SER B 1 197 ? 46.389  -23.162 42.494  1.00 30.97  ? 197 SER B OG  1 
ATOM   3724  N  N   . VAL B 1 198 ? 43.913  -20.859 41.531  1.00 31.18  ? 198 VAL B N   1 
ATOM   3725  C  CA  . VAL B 1 198 ? 43.741  -20.351 40.185  1.00 28.43  ? 198 VAL B CA  1 
ATOM   3726  C  C   . VAL B 1 198 ? 44.875  -20.852 39.289  1.00 27.01  ? 198 VAL B C   1 
ATOM   3727  O  O   . VAL B 1 198 ? 44.617  -21.161 38.132  1.00 27.41  ? 198 VAL B O   1 
ATOM   3728  C  CB  . VAL B 1 198 ? 43.686  -18.814 40.242  1.00 28.13  ? 198 VAL B CB  1 
ATOM   3729  C  CG1 . VAL B 1 198 ? 43.921  -18.184 38.866  1.00 28.09  ? 198 VAL B CG1 1 
ATOM   3730  C  CG2 . VAL B 1 198 ? 42.387  -18.337 40.886  1.00 30.41  ? 198 VAL B CG2 1 
ATOM   3731  N  N   . GLU B 1 199 ? 46.108  -20.923 39.809  1.00 26.87  ? 199 GLU B N   1 
ATOM   3732  C  CA  . GLU B 1 199 ? 47.259  -21.295 38.997  1.00 31.73  ? 199 GLU B CA  1 
ATOM   3733  C  C   . GLU B 1 199 ? 47.085  -22.737 38.506  1.00 28.65  ? 199 GLU B C   1 
ATOM   3734  O  O   . GLU B 1 199 ? 47.374  -23.048 37.352  1.00 30.17  ? 199 GLU B O   1 
ATOM   3735  C  CB  . GLU B 1 199 ? 48.604  -21.071 39.703  1.00 37.50  ? 199 GLU B CB  1 
ATOM   3736  C  CG  . GLU B 1 199 ? 48.853  -19.600 40.095  1.00 40.51  ? 199 GLU B CG  1 
ATOM   3737  C  CD  . GLU B 1 199 ? 48.023  -18.937 41.215  1.00 37.37  ? 199 GLU B CD  1 
ATOM   3738  O  OE1 . GLU B 1 199 ? 47.362  -19.530 42.093  1.00 30.08  ? 199 GLU B OE1 1 
ATOM   3739  O  OE2 . GLU B 1 199 ? 48.101  -17.689 41.213  1.00 40.15  ? 199 GLU B OE2 1 
ATOM   3740  N  N   . ALA B 1 200 ? 46.529  -23.596 39.371  1.00 25.96  ? 200 ALA B N   1 
ATOM   3741  C  CA  . ALA B 1 200 ? 46.233  -24.978 39.019  1.00 24.95  ? 200 ALA B CA  1 
ATOM   3742  C  C   . ALA B 1 200 ? 45.145  -25.084 37.930  1.00 27.48  ? 200 ALA B C   1 
ATOM   3743  O  O   . ALA B 1 200 ? 45.190  -25.949 37.047  1.00 29.14  ? 200 ALA B O   1 
ATOM   3744  C  CB  . ALA B 1 200 ? 45.833  -25.719 40.269  1.00 24.68  ? 200 ALA B CB  1 
ATOM   3745  N  N   . GLN B 1 201 ? 44.128  -24.227 38.029  1.00 28.72  ? 201 GLN B N   1 
ATOM   3746  C  CA  . GLN B 1 201 ? 43.054  -24.227 37.056  1.00 26.77  ? 201 GLN B CA  1 
ATOM   3747  C  C   . GLN B 1 201 ? 43.591  -23.784 35.698  1.00 24.13  ? 201 GLN B C   1 
ATOM   3748  O  O   . GLN B 1 201 ? 43.175  -24.317 34.672  1.00 24.35  ? 201 GLN B O   1 
ATOM   3749  C  CB  . GLN B 1 201 ? 41.934  -23.293 37.495  1.00 27.46  ? 201 GLN B CB  1 
ATOM   3750  C  CG  . GLN B 1 201 ? 41.197  -23.695 38.760  1.00 27.41  ? 201 GLN B CG  1 
ATOM   3751  C  CD  . GLN B 1 201 ? 40.075  -22.763 39.102  1.00 26.53  ? 201 GLN B CD  1 
ATOM   3752  O  OE1 . GLN B 1 201 ? 39.987  -21.659 38.590  1.00 24.93  ? 201 GLN B OE1 1 
ATOM   3753  N  NE2 . GLN B 1 201 ? 39.180  -23.202 39.953  1.00 24.33  ? 201 GLN B NE2 1 
ATOM   3754  N  N   . GLU B 1 202 ? 44.509  -22.817 35.710  1.00 22.76  ? 202 GLU B N   1 
ATOM   3755  C  CA  . GLU B 1 202 ? 45.083  -22.298 34.480  1.00 25.33  ? 202 GLU B CA  1 
ATOM   3756  C  C   . GLU B 1 202 ? 45.883  -23.396 33.772  1.00 30.73  ? 202 GLU B C   1 
ATOM   3757  O  O   . GLU B 1 202 ? 45.999  -23.416 32.549  1.00 32.12  ? 202 GLU B O   1 
ATOM   3758  C  CB  . GLU B 1 202 ? 45.985  -21.095 34.757  1.00 26.43  ? 202 GLU B CB  1 
ATOM   3759  C  CG  . GLU B 1 202 ? 45.218  -19.852 35.190  1.00 27.29  ? 202 GLU B CG  1 
ATOM   3760  C  CD  . GLU B 1 202 ? 46.054  -18.693 35.709  1.00 27.20  ? 202 GLU B CD  1 
ATOM   3761  O  OE1 . GLU B 1 202 ? 47.198  -18.930 36.108  1.00 27.77  ? 202 GLU B OE1 1 
ATOM   3762  O  OE2 . GLU B 1 202 ? 45.572  -17.539 35.659  1.00 28.79  ? 202 GLU B OE2 1 
ATOM   3763  N  N   . ARG B 1 203 ? 46.439  -24.314 34.562  1.00 34.69  ? 203 ARG B N   1 
ATOM   3764  C  CA  . ARG B 1 203 ? 47.218  -25.425 34.048  1.00 34.74  ? 203 ARG B CA  1 
ATOM   3765  C  C   . ARG B 1 203 ? 46.293  -26.470 33.460  1.00 31.38  ? 203 ARG B C   1 
ATOM   3766  O  O   . ARG B 1 203 ? 46.677  -27.196 32.563  1.00 33.83  ? 203 ARG B O   1 
ATOM   3767  C  CB  . ARG B 1 203 ? 48.112  -26.040 35.133  1.00 42.48  ? 203 ARG B CB  1 
ATOM   3768  C  CG  . ARG B 1 203 ? 49.454  -25.327 35.251  1.00 48.92  ? 203 ARG B CG  1 
ATOM   3769  C  CD  . ARG B 1 203 ? 50.560  -26.159 35.930  1.00 55.75  ? 203 ARG B CD  1 
ATOM   3770  N  NE  . ARG B 1 203 ? 50.449  -26.049 37.390  1.00 63.35  ? 203 ARG B NE  1 
ATOM   3771  C  CZ  . ARG B 1 203 ? 50.651  -24.923 38.105  1.00 84.99  ? 203 ARG B CZ  1 
ATOM   3772  N  NH1 . ARG B 1 203 ? 50.888  -23.757 37.499  1.00 95.79  ? 203 ARG B NH1 1 
ATOM   3773  N  NH2 . ARG B 1 203 ? 50.598  -24.950 39.432  1.00 79.55  ? 203 ARG B NH2 1 
ATOM   3774  N  N   . VAL B 1 204 ? 45.071  -26.547 33.969  1.00 30.01  ? 204 VAL B N   1 
ATOM   3775  C  CA  . VAL B 1 204 ? 44.088  -27.437 33.375  1.00 30.63  ? 204 VAL B CA  1 
ATOM   3776  C  C   . VAL B 1 204 ? 43.604  -26.914 32.018  1.00 31.30  ? 204 VAL B C   1 
ATOM   3777  O  O   . VAL B 1 204 ? 43.422  -27.695 31.077  1.00 27.31  ? 204 VAL B O   1 
ATOM   3778  C  CB  . VAL B 1 204 ? 42.916  -27.663 34.328  1.00 29.68  ? 204 VAL B CB  1 
ATOM   3779  C  CG1 . VAL B 1 204 ? 41.802  -28.436 33.630  1.00 28.86  ? 204 VAL B CG1 1 
ATOM   3780  C  CG2 . VAL B 1 204 ? 43.401  -28.408 35.545  1.00 30.92  ? 204 VAL B CG2 1 
ATOM   3781  N  N   . ILE B 1 205 ? 43.364  -25.604 31.923  1.00 27.94  ? 205 ILE B N   1 
ATOM   3782  C  CA  . ILE B 1 205 ? 42.759  -25.065 30.722  1.00 28.29  ? 205 ILE B CA  1 
ATOM   3783  C  C   . ILE B 1 205 ? 43.845  -24.770 29.691  1.00 25.36  ? 205 ILE B C   1 
ATOM   3784  O  O   . ILE B 1 205 ? 43.727  -25.124 28.525  1.00 24.67  ? 205 ILE B O   1 
ATOM   3785  C  CB  . ILE B 1 205 ? 41.922  -23.827 31.092  1.00 29.17  ? 205 ILE B CB  1 
ATOM   3786  C  CG1 . ILE B 1 205 ? 40.800  -24.172 32.051  1.00 30.29  ? 205 ILE B CG1 1 
ATOM   3787  C  CG2 . ILE B 1 205 ? 41.372  -23.133 29.857  1.00 33.63  ? 205 ILE B CG2 1 
ATOM   3788  C  CD1 . ILE B 1 205 ? 39.759  -25.117 31.492  1.00 29.77  ? 205 ILE B CD1 1 
ATOM   3789  N  N   . GLY B 1 206 ? 44.884  -24.080 30.133  1.00 25.48  ? 206 GLY B N   1 
ATOM   3790  C  CA  . GLY B 1 206 ? 45.977  -23.681 29.273  1.00 26.42  ? 206 GLY B CA  1 
ATOM   3791  C  C   . GLY B 1 206 ? 45.970  -22.191 28.967  1.00 25.73  ? 206 GLY B C   1 
ATOM   3792  O  O   . GLY B 1 206 ? 46.705  -21.741 28.097  1.00 30.05  ? 206 GLY B O   1 
ATOM   3793  N  N   . ARG B 1 207 ? 45.150  -21.432 29.683  1.00 25.26  ? 207 ARG B N   1 
ATOM   3794  C  CA  . ARG B 1 207 ? 45.152  -19.982 29.550  1.00 25.93  ? 207 ARG B CA  1 
ATOM   3795  C  C   . ARG B 1 207 ? 45.034  -19.373 30.928  1.00 24.84  ? 207 ARG B C   1 
ATOM   3796  O  O   . ARG B 1 207 ? 44.614  -20.052 31.863  1.00 26.78  ? 207 ARG B O   1 
ATOM   3797  C  CB  . ARG B 1 207 ? 43.934  -19.515 28.745  1.00 26.09  ? 207 ARG B CB  1 
ATOM   3798  C  CG  . ARG B 1 207 ? 43.699  -20.273 27.443  1.00 26.32  ? 207 ARG B CG  1 
ATOM   3799  C  CD  . ARG B 1 207 ? 42.493  -19.756 26.698  1.00 30.16  ? 207 ARG B CD  1 
ATOM   3800  N  NE  . ARG B 1 207 ? 42.689  -18.402 26.140  1.00 33.21  ? 207 ARG B NE  1 
ATOM   3801  C  CZ  . ARG B 1 207 ? 43.219  -18.029 24.957  1.00 33.30  ? 207 ARG B CZ  1 
ATOM   3802  N  NH1 . ARG B 1 207 ? 43.498  -16.757 24.819  1.00 30.30  ? 207 ARG B NH1 1 
ATOM   3803  N  NH2 . ARG B 1 207 ? 43.483  -18.875 23.946  1.00 32.31  ? 207 ARG B NH2 1 
ATOM   3804  N  N   . ARG B 1 208 ? 45.332  -18.081 31.022  1.00 25.63  ? 208 ARG B N   1 
ATOM   3805  C  CA  . ARG B 1 208 ? 45.238  -17.342 32.278  1.00 30.10  ? 208 ARG B CA  1 
ATOM   3806  C  C   . ARG B 1 208 ? 43.776  -17.059 32.591  1.00 27.76  ? 208 ARG B C   1 
ATOM   3807  O  O   . ARG B 1 208 ? 43.013  -16.695 31.715  1.00 28.30  ? 208 ARG B O   1 
ATOM   3808  C  CB  . ARG B 1 208 ? 45.896  -15.958 32.236  1.00 34.96  ? 208 ARG B CB  1 
ATOM   3809  C  CG  . ARG B 1 208 ? 47.370  -15.943 31.864  1.00 43.99  ? 208 ARG B CG  1 
ATOM   3810  C  CD  . ARG B 1 208 ? 48.254  -16.783 32.779  1.00 45.35  ? 208 ARG B CD  1 
ATOM   3811  N  NE  . ARG B 1 208 ? 48.184  -16.345 34.180  1.00 50.20  ? 208 ARG B NE  1 
ATOM   3812  C  CZ  . ARG B 1 208 ? 48.648  -15.152 34.602  1.00 55.57  ? 208 ARG B CZ  1 
ATOM   3813  N  NH1 . ARG B 1 208 ? 49.444  -14.435 33.814  1.00 66.01  ? 208 ARG B NH1 1 
ATOM   3814  N  NH2 . ARG B 1 208 ? 48.365  -14.673 35.808  1.00 47.38  ? 208 ARG B NH2 1 
ATOM   3815  N  N   . LYS B 1 209 ? 43.397  -17.165 33.856  1.00 29.72  ? 209 LYS B N   1 
ATOM   3816  C  CA  . LYS B 1 209 ? 41.988  -17.081 34.204  1.00 27.49  ? 209 LYS B CA  1 
ATOM   3817  C  C   . LYS B 1 209 ? 41.475  -15.652 34.056  1.00 27.58  ? 209 LYS B C   1 
ATOM   3818  O  O   . LYS B 1 209 ? 40.524  -15.437 33.282  1.00 34.45  ? 209 LYS B O   1 
ATOM   3819  C  CB  . LYS B 1 209 ? 41.723  -17.590 35.614  1.00 27.94  ? 209 LYS B CB  1 
ATOM   3820  C  CG  . LYS B 1 209 ? 40.270  -17.754 35.885  1.00 26.05  ? 209 LYS B CG  1 
ATOM   3821  C  CD  . LYS B 1 209 ? 39.984  -18.467 37.184  1.00 26.44  ? 209 LYS B CD  1 
ATOM   3822  C  CE  . LYS B 1 209 ? 38.573  -18.944 37.172  1.00 30.53  ? 209 LYS B CE  1 
ATOM   3823  N  NZ  . LYS B 1 209 ? 38.214  -19.453 38.492  1.00 34.07  ? 209 LYS B NZ  1 
ATOM   3824  N  N   . MET B 1 210 ? 42.103  -14.693 34.752  1.00 25.40  ? 210 MET B N   1 
ATOM   3825  C  CA  . MET B 1 210 ? 41.589  -13.339 34.721  1.00 31.67  ? 210 MET B CA  1 
ATOM   3826  C  C   . MET B 1 210 ? 41.782  -12.654 33.365  1.00 30.87  ? 210 MET B C   1 
ATOM   3827  O  O   . MET B 1 210 ? 40.830  -12.083 32.886  1.00 32.60  ? 210 MET B O   1 
ATOM   3828  C  CB  . MET B 1 210 ? 42.165  -12.421 35.785  1.00 38.14  ? 210 MET B CB  1 
ATOM   3829  C  CG  . MET B 1 210 ? 41.630  -11.043 35.455  1.00 52.16  ? 210 MET B CG  1 
ATOM   3830  S  SD  . MET B 1 210 ? 41.226  -10.084 36.913  1.00 77.79  ? 210 MET B SD  1 
ATOM   3831  C  CE  . MET B 1 210 ? 42.829  -9.249  36.871  1.00 74.00  ? 210 MET B CE  1 
ATOM   3832  N  N   . THR B 1 211 ? 42.957  -12.742 32.724  1.00 31.98  ? 211 THR B N   1 
ATOM   3833  C  CA  . THR B 1 211 ? 43.254  -11.990 31.510  1.00 27.42  ? 211 THR B CA  1 
ATOM   3834  C  C   . THR B 1 211 ? 42.981  -12.783 30.236  1.00 26.04  ? 211 THR B C   1 
ATOM   3835  O  O   . THR B 1 211 ? 42.981  -12.205 29.161  1.00 30.55  ? 211 THR B O   1 
ATOM   3836  C  CB  . THR B 1 211 ? 44.702  -11.504 31.514  1.00 27.26  ? 211 THR B CB  1 
ATOM   3837  O  OG1 . THR B 1 211 ? 45.560  -12.652 31.523  1.00 28.88  ? 211 THR B OG1 1 
ATOM   3838  C  CG2 . THR B 1 211 ? 44.904  -10.530 32.654  1.00 26.87  ? 211 THR B CG2 1 
ATOM   3839  N  N   . ASP B 1 212 ? 42.789  -14.091 30.318  1.00 23.77  ? 212 ASP B N   1 
ATOM   3840  C  CA  . ASP B 1 212 ? 42.527  -14.921 29.145  1.00 25.70  ? 212 ASP B CA  1 
ATOM   3841  C  C   . ASP B 1 212 ? 43.669  -14.890 28.137  1.00 25.47  ? 212 ASP B C   1 
ATOM   3842  O  O   . ASP B 1 212 ? 43.430  -15.116 26.977  1.00 26.25  ? 212 ASP B O   1 
ATOM   3843  C  CB  . ASP B 1 212 ? 41.244  -14.533 28.431  1.00 27.39  ? 212 ASP B CB  1 
ATOM   3844  C  CG  . ASP B 1 212 ? 40.638  -15.550 27.474  1.00 29.68  ? 212 ASP B CG  1 
ATOM   3845  O  OD1 . ASP B 1 212 ? 40.787  -16.818 27.715  1.00 32.76  ? 212 ASP B OD1 1 
ATOM   3846  O  OD2 . ASP B 1 212 ? 39.924  -15.043 26.559  1.00 32.98  ? 212 ASP B OD2 1 
ATOM   3847  N  N   . VAL B 1 213 ? 44.904  -14.695 28.593  1.00 31.56  ? 213 VAL B N   1 
ATOM   3848  C  CA  . VAL B 1 213 ? 46.075  -14.829 27.731  1.00 32.77  ? 213 VAL B CA  1 
ATOM   3849  C  C   . VAL B 1 213 ? 46.556  -16.276 27.738  1.00 33.28  ? 213 VAL B C   1 
ATOM   3850  O  O   . VAL B 1 213 ? 46.710  -16.872 28.805  1.00 32.85  ? 213 VAL B O   1 
ATOM   3851  C  CB  . VAL B 1 213 ? 47.212  -13.896 28.185  1.00 32.26  ? 213 VAL B CB  1 
ATOM   3852  C  CG1 . VAL B 1 213 ? 48.444  -14.061 27.297  1.00 32.49  ? 213 VAL B CG1 1 
ATOM   3853  C  CG2 . VAL B 1 213 ? 46.778  -12.449 28.197  1.00 33.51  ? 213 VAL B CG2 1 
ATOM   3854  N  N   . GLU B 1 214 ? 46.831  -16.822 26.549  1.00 34.60  ? 214 GLU B N   1 
ATOM   3855  C  CA  . GLU B 1 214 ? 47.303  -18.191 26.434  1.00 36.55  ? 214 GLU B CA  1 
ATOM   3856  C  C   . GLU B 1 214 ? 48.603  -18.390 27.220  1.00 33.99  ? 214 GLU B C   1 
ATOM   3857  O  O   . GLU B 1 214 ? 49.441  -17.508 27.237  1.00 34.79  ? 214 GLU B O   1 
ATOM   3858  C  CB  . GLU B 1 214 ? 47.508  -18.409 24.941  1.00 38.80  ? 214 GLU B CB  1 
ATOM   3859  C  CG  . GLU B 1 214 ? 47.754  -19.861 24.579  1.00 41.99  ? 214 GLU B CG  1 
ATOM   3860  C  CD  . GLU B 1 214 ? 47.429  -20.159 23.127  1.00 47.78  ? 214 GLU B CD  1 
ATOM   3861  O  OE1 . GLU B 1 214 ? 46.780  -19.381 22.353  1.00 50.04  ? 214 GLU B OE1 1 
ATOM   3862  O  OE2 . GLU B 1 214 ? 47.762  -21.315 22.838  1.00 52.24  ? 214 GLU B OE2 1 
ATOM   3863  N  N   . LEU B 1 215 ? 48.765  -19.517 27.910  1.00 28.46  ? 215 LEU B N   1 
ATOM   3864  C  CA  . LEU B 1 215 ? 50.032  -19.811 28.547  1.00 33.06  ? 215 LEU B CA  1 
ATOM   3865  C  C   . LEU B 1 215 ? 51.056  -20.073 27.446  1.00 38.06  ? 215 LEU B C   1 
ATOM   3866  O  O   . LEU B 1 215 ? 50.728  -20.721 26.461  1.00 39.36  ? 215 LEU B O   1 
ATOM   3867  C  CB  . LEU B 1 215 ? 49.942  -21.063 29.426  1.00 34.29  ? 215 LEU B CB  1 
ATOM   3868  C  CG  . LEU B 1 215 ? 49.038  -20.995 30.659  1.00 32.87  ? 215 LEU B CG  1 
ATOM   3869  C  CD1 . LEU B 1 215 ? 49.240  -22.249 31.487  1.00 32.77  ? 215 LEU B CD1 1 
ATOM   3870  C  CD2 . LEU B 1 215 ? 49.360  -19.755 31.444  1.00 32.87  ? 215 LEU B CD2 1 
ATOM   3871  N  N   . SER B 1 216 ? 52.305  -19.623 27.648  1.00 46.77  ? 216 SER B N   1 
ATOM   3872  C  CA  . SER B 1 216 ? 53.351  -19.785 26.648  1.00 51.71  ? 216 SER B CA  1 
ATOM   3873  C  C   . SER B 1 216 ? 53.686  -21.266 26.486  1.00 53.77  ? 216 SER B C   1 
ATOM   3874  O  O   . SER B 1 216 ? 53.453  -22.070 27.396  1.00 51.14  ? 216 SER B O   1 
ATOM   3875  C  CB  . SER B 1 216 ? 54.558  -18.971 27.002  1.00 51.54  ? 216 SER B CB  1 
ATOM   3876  O  OG  . SER B 1 216 ? 55.121  -19.406 28.230  1.00 51.89  ? 216 SER B OG  1 
ATOM   3877  N  N   . ASP B 1 217 ? 54.230  -21.592 25.306  1.00 56.09  ? 217 ASP B N   1 
ATOM   3878  C  CA  . ASP B 1 217 ? 54.516  -22.960 24.882  1.00 61.61  ? 217 ASP B CA  1 
ATOM   3879  C  C   . ASP B 1 217 ? 55.419  -23.644 25.908  1.00 53.52  ? 217 ASP B C   1 
ATOM   3880  O  O   . ASP B 1 217 ? 55.291  -24.849 26.147  1.00 46.47  ? 217 ASP B O   1 
ATOM   3881  C  CB  . ASP B 1 217 ? 55.206  -23.027 23.527  1.00 61.93  ? 217 ASP B CB  1 
ATOM   3882  C  CG  . ASP B 1 217 ? 54.489  -22.291 22.413  1.00 77.80  ? 217 ASP B CG  1 
ATOM   3883  O  OD1 . ASP B 1 217 ? 53.333  -22.682 22.144  1.00 87.18  ? 217 ASP B OD1 1 
ATOM   3884  O  OD2 . ASP B 1 217 ? 55.078  -21.318 21.874  1.00 89.34  ? 217 ASP B OD2 1 
ATOM   3885  N  N   . ASP B 1 218 ? 56.318  -22.852 26.517  1.00 54.17  ? 218 ASP B N   1 
ATOM   3886  C  CA  . ASP B 1 218 ? 57.289  -23.428 27.424  1.00 62.16  ? 218 ASP B CA  1 
ATOM   3887  C  C   . ASP B 1 218 ? 56.630  -23.778 28.760  1.00 55.29  ? 218 ASP B C   1 
ATOM   3888  O  O   . ASP B 1 218 ? 57.211  -24.502 29.539  1.00 63.17  ? 218 ASP B O   1 
ATOM   3889  C  CB  . ASP B 1 218 ? 58.611  -22.662 27.413  1.00 68.60  ? 218 ASP B CB  1 
ATOM   3890  C  CG  . ASP B 1 218 ? 58.706  -21.353 28.178  1.00 72.59  ? 218 ASP B CG  1 
ATOM   3891  O  OD1 . ASP B 1 218 ? 57.678  -20.908 28.707  1.00 72.91  ? 218 ASP B OD1 1 
ATOM   3892  O  OD2 . ASP B 1 218 ? 59.837  -20.827 28.279  1.00 81.24  ? 218 ASP B OD2 1 
ATOM   3893  N  N   . VAL B 1 219 ? 55.405  -23.344 29.055  1.00 52.96  ? 219 VAL B N   1 
ATOM   3894  C  CA  . VAL B 1 219 ? 54.829  -23.656 30.368  1.00 43.99  ? 219 VAL B CA  1 
ATOM   3895  C  C   . VAL B 1 219 ? 53.454  -24.340 30.258  1.00 43.54  ? 219 VAL B C   1 
ATOM   3896  O  O   . VAL B 1 219 ? 52.869  -24.802 31.236  1.00 37.07  ? 219 VAL B O   1 
ATOM   3897  C  CB  . VAL B 1 219 ? 54.780  -22.356 31.196  1.00 41.77  ? 219 VAL B CB  1 
ATOM   3898  C  CG1 . VAL B 1 219 ? 54.173  -21.217 30.404  1.00 44.04  ? 219 VAL B CG1 1 
ATOM   3899  C  CG2 . VAL B 1 219 ? 53.996  -22.475 32.484  1.00 40.23  ? 219 VAL B CG2 1 
ATOM   3900  N  N   . LYS B 1 220 ? 52.919  -24.450 29.049  1.00 44.79  ? 220 LYS B N   1 
ATOM   3901  C  CA  . LYS B 1 220 ? 51.588  -24.995 28.936  1.00 47.91  ? 220 LYS B CA  1 
ATOM   3902  C  C   . LYS B 1 220 ? 51.696  -26.503 29.055  1.00 42.18  ? 220 LYS B C   1 
ATOM   3903  O  O   . LYS B 1 220 ? 52.351  -27.119 28.230  1.00 48.52  ? 220 LYS B O   1 
ATOM   3904  C  CB  . LYS B 1 220 ? 51.007  -24.579 27.582  1.00 57.38  ? 220 LYS B CB  1 
ATOM   3905  C  CG  . LYS B 1 220 ? 49.593  -25.070 27.278  1.00 57.18  ? 220 LYS B CG  1 
ATOM   3906  C  CD  . LYS B 1 220 ? 49.201  -24.941 25.810  1.00 55.34  ? 220 LYS B CD  1 
ATOM   3907  C  CE  . LYS B 1 220 ? 49.747  -23.637 25.281  1.00 59.46  ? 220 LYS B CE  1 
ATOM   3908  N  NZ  . LYS B 1 220 ? 48.944  -23.048 24.211  1.00 60.84  ? 220 LYS B NZ  1 
ATOM   3909  N  N   . PRO B 1 221 ? 51.047  -27.156 30.039  1.00 33.54  ? 221 PRO B N   1 
ATOM   3910  C  CA  . PRO B 1 221 ? 51.018  -28.616 30.084  1.00 30.22  ? 221 PRO B CA  1 
ATOM   3911  C  C   . PRO B 1 221 ? 50.473  -29.283 28.825  1.00 32.05  ? 221 PRO B C   1 
ATOM   3912  O  O   . PRO B 1 221 ? 49.599  -28.755 28.149  1.00 32.55  ? 221 PRO B O   1 
ATOM   3913  C  CB  . PRO B 1 221 ? 50.145  -28.939 31.303  1.00 29.80  ? 221 PRO B CB  1 
ATOM   3914  C  CG  . PRO B 1 221 ? 50.230  -27.695 32.163  1.00 28.65  ? 221 PRO B CG  1 
ATOM   3915  C  CD  . PRO B 1 221 ? 50.337  -26.551 31.169  1.00 32.59  ? 221 PRO B CD  1 
ATOM   3916  N  N   . ALA B 1 222 ? 50.996  -30.481 28.534  1.00 32.79  ? 222 ALA B N   1 
ATOM   3917  C  CA  . ALA B 1 222 ? 50.578  -31.255 27.385  1.00 35.11  ? 222 ALA B CA  1 
ATOM   3918  C  C   . ALA B 1 222 ? 49.186  -31.849 27.596  1.00 35.56  ? 222 ALA B C   1 
ATOM   3919  O  O   . ALA B 1 222 ? 48.550  -32.248 26.623  1.00 44.04  ? 222 ALA B O   1 
ATOM   3920  C  CB  . ALA B 1 222 ? 51.591  -32.335 27.115  1.00 36.20  ? 222 ALA B CB  1 
ATOM   3921  N  N   . ASP B 1 223 ? 48.728  -31.952 28.850  1.00 34.86  ? 223 ASP B N   1 
ATOM   3922  C  CA  . ASP B 1 223 ? 47.401  -32.500 29.117  1.00 34.85  ? 223 ASP B CA  1 
ATOM   3923  C  C   . ASP B 1 223 ? 46.407  -31.381 29.453  1.00 32.63  ? 223 ASP B C   1 
ATOM   3924  O  O   . ASP B 1 223 ? 45.307  -31.644 29.937  1.00 32.07  ? 223 ASP B O   1 
ATOM   3925  C  CB  . ASP B 1 223 ? 47.439  -33.606 30.156  1.00 36.37  ? 223 ASP B CB  1 
ATOM   3926  C  CG  . ASP B 1 223 ? 47.894  -33.199 31.547  1.00 37.99  ? 223 ASP B CG  1 
ATOM   3927  O  OD1 . ASP B 1 223 ? 48.498  -32.092 31.673  1.00 36.08  ? 223 ASP B OD1 1 
ATOM   3928  O  OD2 . ASP B 1 223 ? 47.612  -33.994 32.472  1.00 38.01  ? 223 ASP B OD2 1 
ATOM   3929  N  N   . SER B 1 224 ? 46.781  -30.133 29.155  1.00 33.52  ? 224 SER B N   1 
ATOM   3930  C  CA  . SER B 1 224 ? 45.858  -29.020 29.256  1.00 31.75  ? 224 SER B CA  1 
ATOM   3931  C  C   . SER B 1 224 ? 44.882  -29.087 28.083  1.00 30.53  ? 224 SER B C   1 
ATOM   3932  O  O   . SER B 1 224 ? 45.177  -29.676 27.053  1.00 24.17  ? 224 SER B O   1 
ATOM   3933  C  CB  . SER B 1 224 ? 46.587  -27.686 29.303  1.00 30.98  ? 224 SER B CB  1 
ATOM   3934  O  OG  . SER B 1 224 ? 47.171  -27.372 28.047  1.00 32.07  ? 224 SER B OG  1 
ATOM   3935  N  N   . HIS B 1 225 ? 43.715  -28.472 28.275  1.00 31.63  ? 225 HIS B N   1 
ATOM   3936  C  CA  . HIS B 1 225 ? 42.605  -28.582 27.348  1.00 32.74  ? 225 HIS B CA  1 
ATOM   3937  C  C   . HIS B 1 225 ? 42.978  -27.944 26.012  1.00 31.72  ? 225 HIS B C   1 
ATOM   3938  O  O   . HIS B 1 225 ? 42.678  -28.488 24.956  1.00 29.00  ? 225 HIS B O   1 
ATOM   3939  C  CB  . HIS B 1 225 ? 41.350  -27.965 27.988  1.00 29.49  ? 225 HIS B CB  1 
ATOM   3940  C  CG  . HIS B 1 225 ? 40.177  -27.918 27.111  1.00 24.73  ? 225 HIS B CG  1 
ATOM   3941  N  ND1 . HIS B 1 225 ? 39.613  -29.063 26.594  1.00 23.89  ? 225 HIS B ND1 1 
ATOM   3942  C  CD2 . HIS B 1 225 ? 39.484  -26.887 26.610  1.00 24.34  ? 225 HIS B CD2 1 
ATOM   3943  C  CE1 . HIS B 1 225 ? 38.571  -28.736 25.821  1.00 24.06  ? 225 HIS B CE1 1 
ATOM   3944  N  NE2 . HIS B 1 225 ? 38.438  -27.420 25.848  1.00 23.07  ? 225 HIS B NE2 1 
ATOM   3945  N  N   . VAL B 1 226 ? 43.646  -26.790 26.068  1.00 30.19  ? 226 VAL B N   1 
ATOM   3946  C  CA  . VAL B 1 226 ? 44.001  -26.065 24.855  1.00 32.66  ? 226 VAL B CA  1 
ATOM   3947  C  C   . VAL B 1 226 ? 45.101  -26.808 24.096  1.00 33.21  ? 226 VAL B C   1 
ATOM   3948  O  O   . VAL B 1 226 ? 45.172  -26.744 22.864  1.00 29.93  ? 226 VAL B O   1 
ATOM   3949  C  CB  . VAL B 1 226 ? 44.424  -24.628 25.204  1.00 37.32  ? 226 VAL B CB  1 
ATOM   3950  C  CG1 . VAL B 1 226 ? 45.343  -24.017 24.156  1.00 37.31  ? 226 VAL B CG1 1 
ATOM   3951  C  CG2 . VAL B 1 226 ? 43.210  -23.739 25.464  1.00 43.26  ? 226 VAL B CG2 1 
ATOM   3952  N  N   . ALA B 1 227 ? 45.973  -27.488 24.840  1.00 34.42  ? 227 ALA B N   1 
ATOM   3953  C  CA  . ALA B 1 227 ? 47.017  -28.301 24.239  1.00 37.43  ? 227 ALA B CA  1 
ATOM   3954  C  C   . ALA B 1 227 ? 46.397  -29.436 23.431  1.00 34.84  ? 227 ALA B C   1 
ATOM   3955  O  O   . ALA B 1 227 ? 46.724  -29.589 22.255  1.00 33.63  ? 227 ALA B O   1 
ATOM   3956  C  CB  . ALA B 1 227 ? 47.975  -28.813 25.293  1.00 36.13  ? 227 ALA B CB  1 
ATOM   3957  N  N   . LEU B 1 228 ? 45.468  -30.185 24.034  1.00 33.41  ? 228 LEU B N   1 
ATOM   3958  C  CA  . LEU B 1 228 ? 44.925  -31.352 23.371  1.00 34.67  ? 228 LEU B CA  1 
ATOM   3959  C  C   . LEU B 1 228 ? 43.918  -31.005 22.281  1.00 40.17  ? 228 LEU B C   1 
ATOM   3960  O  O   . LEU B 1 228 ? 43.664  -31.865 21.450  1.00 37.92  ? 228 LEU B O   1 
ATOM   3961  C  CB  . LEU B 1 228 ? 44.283  -32.285 24.381  1.00 35.93  ? 228 LEU B CB  1 
ATOM   3962  C  CG  . LEU B 1 228 ? 45.255  -32.959 25.341  1.00 39.53  ? 228 LEU B CG  1 
ATOM   3963  C  CD1 . LEU B 1 228 ? 44.480  -33.585 26.466  1.00 41.88  ? 228 LEU B CD1 1 
ATOM   3964  C  CD2 . LEU B 1 228 ? 46.000  -33.989 24.574  1.00 41.56  ? 228 LEU B CD2 1 
ATOM   3965  N  N   . THR B 1 229 ? 43.304  -29.810 22.285  1.00 38.03  ? 229 THR B N   1 
ATOM   3966  C  CA  . THR B 1 229 ? 42.312  -29.511 21.262  1.00 36.13  ? 229 THR B CA  1 
ATOM   3967  C  C   . THR B 1 229 ? 42.907  -28.650 20.150  1.00 40.36  ? 229 THR B C   1 
ATOM   3968  O  O   . THR B 1 229 ? 42.157  -28.189 19.290  1.00 46.82  ? 229 THR B O   1 
ATOM   3969  C  CB  . THR B 1 229 ? 41.090  -28.836 21.883  1.00 32.40  ? 229 THR B CB  1 
ATOM   3970  O  OG1 . THR B 1 229 ? 41.481  -27.640 22.553  1.00 29.39  ? 229 THR B OG1 1 
ATOM   3971  C  CG2 . THR B 1 229 ? 40.342  -29.765 22.817  1.00 35.43  ? 229 THR B CG2 1 
ATOM   3972  N  N   . SER B 1 230 ? 44.227  -28.390 20.197  1.00 41.52  ? 230 SER B N   1 
ATOM   3973  C  CA  . SER B 1 230 ? 44.946  -27.808 19.066  1.00 42.59  ? 230 SER B CA  1 
ATOM   3974  C  C   . SER B 1 230 ? 45.470  -28.934 18.193  1.00 43.10  ? 230 SER B C   1 
ATOM   3975  O  O   . SER B 1 230 ? 46.244  -29.747 18.650  1.00 50.16  ? 230 SER B O   1 
ATOM   3976  C  CB  . SER B 1 230 ? 46.063  -26.925 19.504  1.00 41.17  ? 230 SER B CB  1 
ATOM   3977  O  OG  . SER B 1 230 ? 45.554  -25.813 20.223  1.00 42.59  ? 230 SER B OG  1 
ATOM   3978  N  N   . VAL B 1 231 ? 45.020  -28.999 16.946  1.00 46.74  ? 231 VAL B N   1 
ATOM   3979  C  CA  . VAL B 1 231 ? 45.388  -30.067 16.028  1.00 45.73  ? 231 VAL B CA  1 
ATOM   3980  C  C   . VAL B 1 231 ? 45.783  -29.381 14.741  1.00 50.26  ? 231 VAL B C   1 
ATOM   3981  O  O   . VAL B 1 231 ? 45.123  -28.427 14.360  1.00 49.36  ? 231 VAL B O   1 
ATOM   3982  C  CB  . VAL B 1 231 ? 44.173  -30.965 15.795  1.00 47.62  ? 231 VAL B CB  1 
ATOM   3983  C  CG1 . VAL B 1 231 ? 44.303  -31.861 14.571  1.00 49.56  ? 231 VAL B CG1 1 
ATOM   3984  C  CG2 . VAL B 1 231 ? 43.840  -31.742 17.046  1.00 47.09  ? 231 VAL B CG2 1 
ATOM   3985  N  N   . THR B 1 232 ? 46.852  -29.838 14.096  1.00 58.92  ? 232 THR B N   1 
ATOM   3986  C  CA  . THR B 1 232 ? 47.178  -29.330 12.769  1.00 66.40  ? 232 THR B CA  1 
ATOM   3987  C  C   . THR B 1 232 ? 46.928  -30.458 11.764  1.00 73.48  ? 232 THR B C   1 
ATOM   3988  O  O   . THR B 1 232 ? 47.126  -31.644 12.075  1.00 60.23  ? 232 THR B O   1 
ATOM   3989  C  CB  . THR B 1 232 ? 48.601  -28.762 12.706  1.00 57.67  ? 232 THR B CB  1 
ATOM   3990  O  OG1 . THR B 1 232 ? 49.298  -29.878 13.221  1.00 55.56  ? 232 THR B OG1 1 
ATOM   3991  C  CG2 . THR B 1 232 ? 48.814  -27.496 13.527  1.00 55.59  ? 232 THR B CG2 1 
ATOM   3992  N  N   . GLY B 1 233 ? 46.469  -30.061 10.562  1.00 84.48  ? 233 GLY B N   1 
ATOM   3993  C  CA  . GLY B 1 233 ? 46.188  -31.001 9.488   1.00 86.09  ? 233 GLY B CA  1 
ATOM   3994  C  C   . GLY B 1 233 ? 47.481  -31.438 8.811   1.00 89.81  ? 233 GLY B C   1 
ATOM   3995  O  O   . GLY B 1 233 ? 48.549  -30.945 9.165   1.00 95.11  ? 233 GLY B O   1 
ATOM   3996  N  N   . PRO B 1 234 ? 47.439  -32.454 7.923   1.00 86.06  ? 234 PRO B N   1 
ATOM   3997  C  CA  . PRO B 1 234 ? 48.628  -32.863 7.163   1.00 82.38  ? 234 PRO B CA  1 
ATOM   3998  C  C   . PRO B 1 234 ? 49.542  -31.743 6.645   1.00 74.74  ? 234 PRO B C   1 
ATOM   3999  O  O   . PRO B 1 234 ? 50.748  -31.800 6.841   1.00 68.92  ? 234 PRO B O   1 
ATOM   4000  C  CB  . PRO B 1 234 ? 48.001  -33.731 6.049   1.00 82.89  ? 234 PRO B CB  1 
ATOM   4001  C  CG  . PRO B 1 234 ? 46.819  -34.411 6.759   1.00 78.35  ? 234 PRO B CG  1 
ATOM   4002  C  CD  . PRO B 1 234 ? 46.283  -33.343 7.709   1.00 75.84  ? 234 PRO B CD  1 
ATOM   4003  N  N   . ASP B 1 235 ? 48.999  -30.666 6.066   1.00 77.13  ? 235 ASP B N   1 
ATOM   4004  C  CA  . ASP B 1 235 ? 49.866  -29.608 5.549   1.00 84.60  ? 235 ASP B CA  1 
ATOM   4005  C  C   . ASP B 1 235 ? 50.446  -28.716 6.666   1.00 95.67  ? 235 ASP B C   1 
ATOM   4006  O  O   . ASP B 1 235 ? 51.238  -27.825 6.382   1.00 97.10  ? 235 ASP B O   1 
ATOM   4007  C  CB  . ASP B 1 235 ? 49.165  -28.826 4.450   1.00 81.27  ? 235 ASP B CB  1 
ATOM   4008  C  CG  . ASP B 1 235 ? 48.248  -27.719 4.934   1.00 87.61  ? 235 ASP B CG  1 
ATOM   4009  O  OD1 . ASP B 1 235 ? 47.600  -27.909 5.999   1.00 90.57  ? 235 ASP B OD1 1 
ATOM   4010  O  OD2 . ASP B 1 235 ? 48.264  -26.656 4.283   1.00 100.06 ? 235 ASP B OD2 1 
ATOM   4011  N  N   . GLY B 1 236 ? 50.057  -28.898 7.934   1.00 96.96  ? 236 GLY B N   1 
ATOM   4012  C  CA  . GLY B 1 236 ? 50.586  -28.057 9.003   1.00 80.56  ? 236 GLY B CA  1 
ATOM   4013  C  C   . GLY B 1 236 ? 49.727  -26.826 9.294   1.00 77.89  ? 236 GLY B C   1 
ATOM   4014  O  O   . GLY B 1 236 ? 50.084  -26.049 10.165  1.00 70.40  ? 236 GLY B O   1 
ATOM   4015  N  N   . SER B 1 237 ? 48.601  -26.624 8.596   1.00 94.88  ? 237 SER B N   1 
ATOM   4016  C  CA  . SER B 1 237 ? 47.642  -25.604 9.041   1.00 91.83  ? 237 SER B CA  1 
ATOM   4017  C  C   . SER B 1 237 ? 46.727  -26.163 10.146  1.00 79.20  ? 237 SER B C   1 
ATOM   4018  O  O   . SER B 1 237 ? 46.332  -27.338 10.126  1.00 61.50  ? 237 SER B O   1 
ATOM   4019  C  CB  . SER B 1 237 ? 46.850  -24.979 7.896   1.00 71.57  ? 237 SER B CB  1 
ATOM   4020  O  OG  . SER B 1 237 ? 46.149  -25.999 7.215   1.00 63.52  ? 237 SER B OG  1 
ATOM   4021  N  N   . ASP B 1 238 ? 46.404  -25.285 11.106  1.00 65.69  ? 238 ASP B N   1 
ATOM   4022  C  CA  . ASP B 1 238 ? 45.535  -25.594 12.227  1.00 63.33  ? 238 ASP B CA  1 
ATOM   4023  C  C   . ASP B 1 238 ? 44.133  -26.032 11.775  1.00 64.16  ? 238 ASP B C   1 
ATOM   4024  O  O   . ASP B 1 238 ? 43.542  -25.441 10.891  1.00 70.17  ? 238 ASP B O   1 
ATOM   4025  C  CB  . ASP B 1 238 ? 45.464  -24.372 13.120  1.00 64.51  ? 238 ASP B CB  1 
ATOM   4026  C  CG  . ASP B 1 238 ? 46.719  -24.099 13.918  1.00 65.35  ? 238 ASP B CG  1 
ATOM   4027  O  OD1 . ASP B 1 238 ? 47.819  -24.226 13.361  1.00 70.97  ? 238 ASP B OD1 1 
ATOM   4028  O  OD2 . ASP B 1 238 ? 46.565  -23.770 15.097  1.00 73.77  ? 238 ASP B OD2 1 
ATOM   4029  N  N   . LEU B 1 239 ? 43.597  -27.080 12.397  1.00 56.35  ? 239 LEU B N   1 
ATOM   4030  C  CA  . LEU B 1 239 ? 42.230  -27.533 12.189  1.00 51.20  ? 239 LEU B CA  1 
ATOM   4031  C  C   . LEU B 1 239 ? 41.320  -26.901 13.241  1.00 50.16  ? 239 LEU B C   1 
ATOM   4032  O  O   . LEU B 1 239 ? 41.572  -27.051 14.424  1.00 54.86  ? 239 LEU B O   1 
ATOM   4033  C  CB  . LEU B 1 239 ? 42.195  -29.055 12.316  1.00 53.18  ? 239 LEU B CB  1 
ATOM   4034  C  CG  . LEU B 1 239 ? 42.832  -29.843 11.164  1.00 54.28  ? 239 LEU B CG  1 
ATOM   4035  C  CD1 . LEU B 1 239 ? 42.449  -31.306 11.346  1.00 51.21  ? 239 LEU B CD1 1 
ATOM   4036  C  CD2 . LEU B 1 239 ? 42.473  -29.388 9.727   1.00 51.06  ? 239 LEU B CD2 1 
ATOM   4037  N  N   . GLU B 1 240 ? 40.244  -26.237 12.817  1.00 39.26  ? 240 GLU B N   1 
ATOM   4038  C  CA  . GLU B 1 240 ? 39.426  -25.431 13.697  1.00 35.28  ? 240 GLU B CA  1 
ATOM   4039  C  C   . GLU B 1 240 ? 37.977  -25.916 13.670  1.00 33.04  ? 240 GLU B C   1 
ATOM   4040  O  O   . GLU B 1 240 ? 37.483  -26.436 12.676  1.00 29.63  ? 240 GLU B O   1 
ATOM   4041  C  CB  . GLU B 1 240 ? 39.511  -23.994 13.193  1.00 36.14  ? 240 GLU B CB  1 
ATOM   4042  C  CG  . GLU B 1 240 ? 40.934  -23.458 13.083  1.00 41.06  ? 240 GLU B CG  1 
ATOM   4043  C  CD  . GLU B 1 240 ? 40.937  -21.933 13.075  1.00 44.78  ? 240 GLU B CD  1 
ATOM   4044  O  OE1 . GLU B 1 240 ? 40.756  -21.349 12.005  1.00 42.41  ? 240 GLU B OE1 1 
ATOM   4045  O  OE2 . GLU B 1 240 ? 41.069  -21.323 14.151  1.00 51.78  ? 240 GLU B OE2 1 
ATOM   4046  N  N   . ILE B 1 241 ? 37.267  -25.697 14.779  1.00 34.13  ? 241 ILE B N   1 
ATOM   4047  C  CA  . ILE B 1 241 ? 35.820  -25.845 14.841  1.00 29.70  ? 241 ILE B CA  1 
ATOM   4048  C  C   . ILE B 1 241 ? 35.221  -24.548 15.381  1.00 29.44  ? 241 ILE B C   1 
ATOM   4049  O  O   . ILE B 1 241 ? 35.914  -23.648 15.865  1.00 25.75  ? 241 ILE B O   1 
ATOM   4050  C  CB  . ILE B 1 241 ? 35.396  -27.041 15.712  1.00 30.10  ? 241 ILE B CB  1 
ATOM   4051  C  CG1 . ILE B 1 241 ? 35.777  -26.846 17.171  1.00 30.64  ? 241 ILE B CG1 1 
ATOM   4052  C  CG2 . ILE B 1 241 ? 35.972  -28.332 15.153  1.00 33.43  ? 241 ILE B CG2 1 
ATOM   4053  C  CD1 . ILE B 1 241 ? 35.275  -27.953 18.068  1.00 30.56  ? 241 ILE B CD1 1 
ATOM   4054  N  N   . LEU B 1 242 ? 33.893  -24.455 15.297  1.00 31.07  ? 242 LEU B N   1 
ATOM   4055  C  CA  . LEU B 1 242 ? 33.224  -23.300 15.856  1.00 33.79  ? 242 LEU B CA  1 
ATOM   4056  C  C   . LEU B 1 242 ? 32.374  -23.788 17.008  1.00 27.53  ? 242 LEU B C   1 
ATOM   4057  O  O   . LEU B 1 242 ? 31.507  -24.600 16.764  1.00 25.11  ? 242 LEU B O   1 
ATOM   4058  C  CB  . LEU B 1 242 ? 32.354  -22.649 14.788  1.00 39.79  ? 242 LEU B CB  1 
ATOM   4059  C  CG  . LEU B 1 242 ? 31.566  -21.423 15.266  1.00 38.23  ? 242 LEU B CG  1 
ATOM   4060  C  CD1 . LEU B 1 242 ? 32.532  -20.333 15.405  1.00 35.39  ? 242 LEU B CD1 1 
ATOM   4061  C  CD2 . LEU B 1 242 ? 30.474  -21.047 14.351  1.00 37.31  ? 242 LEU B CD2 1 
ATOM   4062  N  N   . ARG B 1 243 ? 32.604  -23.251 18.207  1.00 27.68  ? 243 ARG B N   1 
ATOM   4063  C  CA  . ARG B 1 243 ? 31.915  -23.707 19.407  1.00 30.08  ? 243 ARG B CA  1 
ATOM   4064  C  C   . ARG B 1 243 ? 30.959  -22.646 19.918  1.00 26.91  ? 243 ARG B C   1 
ATOM   4065  O  O   . ARG B 1 243 ? 31.210  -21.480 19.705  1.00 23.40  ? 243 ARG B O   1 
ATOM   4066  C  CB  . ARG B 1 243 ? 32.927  -23.948 20.530  1.00 31.11  ? 243 ARG B CB  1 
ATOM   4067  C  CG  . ARG B 1 243 ? 33.833  -25.143 20.274  1.00 30.98  ? 243 ARG B CG  1 
ATOM   4068  C  CD  . ARG B 1 243 ? 34.956  -25.128 21.304  1.00 30.83  ? 243 ARG B CD  1 
ATOM   4069  N  NE  . ARG B 1 243 ? 35.891  -24.056 20.959  1.00 31.09  ? 243 ARG B NE  1 
ATOM   4070  C  CZ  . ARG B 1 243 ? 36.230  -23.055 21.747  1.00 36.18  ? 243 ARG B CZ  1 
ATOM   4071  N  NH1 . ARG B 1 243 ? 35.866  -23.105 23.014  1.00 37.76  ? 243 ARG B NH1 1 
ATOM   4072  N  NH2 . ARG B 1 243 ? 36.964  -22.040 21.285  1.00 39.39  ? 243 ARG B NH2 1 
ATOM   4073  N  N   . ASP B 1 244 ? 29.903  -23.060 20.629  1.00 25.63  ? 244 ASP B N   1 
ATOM   4074  C  CA  . ASP B 1 244 ? 29.033  -22.103 21.289  1.00 27.52  ? 244 ASP B CA  1 
ATOM   4075  C  C   . ASP B 1 244 ? 28.565  -22.688 22.615  1.00 25.67  ? 244 ASP B C   1 
ATOM   4076  O  O   . ASP B 1 244 ? 27.392  -22.760 22.876  1.00 26.35  ? 244 ASP B O   1 
ATOM   4077  C  CB  . ASP B 1 244 ? 27.951  -21.592 20.353  1.00 26.02  ? 244 ASP B CB  1 
ATOM   4078  C  CG  . ASP B 1 244 ? 27.361  -20.259 20.764  1.00 31.32  ? 244 ASP B CG  1 
ATOM   4079  O  OD1 . ASP B 1 244 ? 27.878  -19.659 21.736  1.00 29.78  ? 244 ASP B OD1 1 
ATOM   4080  O  OD2 . ASP B 1 244 ? 26.373  -19.854 20.130  1.00 36.64  ? 244 ASP B OD2 1 
ATOM   4081  N  N   . ASN B 1 245 ? 29.519  -23.069 23.451  1.00 24.96  ? 245 ASN B N   1 
ATOM   4082  C  CA  . ASN B 1 245 ? 29.257  -23.642 24.756  1.00 27.03  ? 245 ASN B CA  1 
ATOM   4083  C  C   . ASN B 1 245 ? 28.398  -22.695 25.593  1.00 25.07  ? 245 ASN B C   1 
ATOM   4084  O  O   . ASN B 1 245 ? 28.661  -21.493 25.650  1.00 25.18  ? 245 ASN B O   1 
ATOM   4085  C  CB  . ASN B 1 245 ? 30.555  -23.929 25.518  1.00 29.13  ? 245 ASN B CB  1 
ATOM   4086  C  CG  . ASN B 1 245 ? 31.480  -24.811 24.711  1.00 33.41  ? 245 ASN B CG  1 
ATOM   4087  O  OD1 . ASN B 1 245 ? 31.005  -25.465 23.760  1.00 34.71  ? 245 ASN B OD1 1 
ATOM   4088  N  ND2 . ASN B 1 245 ? 32.772  -24.822 25.055  1.00 34.55  ? 245 ASN B ND2 1 
ATOM   4089  N  N   . MET B 1 246 ? 27.429  -23.284 26.292  1.00 23.89  ? 246 MET B N   1 
ATOM   4090  C  CA  . MET B 1 246 ? 26.524  -22.556 27.156  1.00 25.86  ? 246 MET B CA  1 
ATOM   4091  C  C   . MET B 1 246 ? 26.452  -23.223 28.518  1.00 26.64  ? 246 MET B C   1 
ATOM   4092  O  O   . MET B 1 246 ? 26.125  -24.396 28.637  1.00 24.68  ? 246 MET B O   1 
ATOM   4093  C  CB  . MET B 1 246 ? 25.095  -22.523 26.602  1.00 29.06  ? 246 MET B CB  1 
ATOM   4094  C  CG  . MET B 1 246 ? 24.945  -21.745 25.310  1.00 31.27  ? 246 MET B CG  1 
ATOM   4095  S  SD  . MET B 1 246 ? 25.331  -20.006 25.539  1.00 32.77  ? 246 MET B SD  1 
ATOM   4096  C  CE  . MET B 1 246 ? 23.792  -19.556 26.283  1.00 34.40  ? 246 MET B CE  1 
ATOM   4097  N  N   . PRO B 1 247 ? 26.665  -22.457 29.595  1.00 26.44  ? 247 PRO B N   1 
ATOM   4098  C  CA  . PRO B 1 247 ? 26.299  -22.885 30.937  1.00 25.38  ? 247 PRO B CA  1 
ATOM   4099  C  C   . PRO B 1 247 ? 24.811  -23.132 31.091  1.00 24.32  ? 247 PRO B C   1 
ATOM   4100  O  O   . PRO B 1 247 ? 23.981  -22.476 30.468  1.00 25.84  ? 247 PRO B O   1 
ATOM   4101  C  CB  . PRO B 1 247 ? 26.693  -21.710 31.819  1.00 28.05  ? 247 PRO B CB  1 
ATOM   4102  C  CG  . PRO B 1 247 ? 27.608  -20.880 30.966  1.00 26.99  ? 247 PRO B CG  1 
ATOM   4103  C  CD  . PRO B 1 247 ? 27.216  -21.106 29.549  1.00 26.85  ? 247 PRO B CD  1 
ATOM   4104  N  N   . PHE B 1 248 ? 24.500  -24.039 32.003  1.00 25.02  ? 248 PHE B N   1 
ATOM   4105  C  CA  . PHE B 1 248 ? 23.134  -24.279 32.433  1.00 25.42  ? 248 PHE B CA  1 
ATOM   4106  C  C   . PHE B 1 248 ? 23.206  -24.854 33.833  1.00 25.97  ? 248 PHE B C   1 
ATOM   4107  O  O   . PHE B 1 248 ? 24.270  -25.272 34.306  1.00 25.99  ? 248 PHE B O   1 
ATOM   4108  C  CB  . PHE B 1 248 ? 22.420  -25.255 31.514  1.00 24.11  ? 248 PHE B CB  1 
ATOM   4109  C  CG  . PHE B 1 248 ? 22.980  -26.667 31.578  1.00 25.91  ? 248 PHE B CG  1 
ATOM   4110  C  CD1 . PHE B 1 248 ? 24.039  -27.057 30.771  1.00 29.50  ? 248 PHE B CD1 1 
ATOM   4111  C  CD2 . PHE B 1 248 ? 22.415  -27.603 32.419  1.00 25.27  ? 248 PHE B CD2 1 
ATOM   4112  C  CE1 . PHE B 1 248 ? 24.558  -28.340 30.853  1.00 29.83  ? 248 PHE B CE1 1 
ATOM   4113  C  CE2 . PHE B 1 248 ? 22.933  -28.881 32.502  1.00 26.82  ? 248 PHE B CE2 1 
ATOM   4114  C  CZ  . PHE B 1 248 ? 24.011  -29.243 31.722  1.00 29.90  ? 248 PHE B CZ  1 
ATOM   4115  N  N   . GLY B 1 249 ? 22.076  -24.859 34.512  1.00 24.78  ? 249 GLY B N   1 
ATOM   4116  C  CA  . GLY B 1 249 ? 22.071  -25.577 35.763  1.00 24.70  ? 249 GLY B CA  1 
ATOM   4117  C  C   . GLY B 1 249 ? 20.796  -25.422 36.554  1.00 22.85  ? 249 GLY B C   1 
ATOM   4118  O  O   . GLY B 1 249 ? 19.883  -24.705 36.194  1.00 22.20  ? 249 GLY B O   1 
ATOM   4119  N  N   . SER B 1 250 ? 20.860  -26.022 37.727  1.00 29.03  ? 250 SER B N   1 
ATOM   4120  C  CA  . SER B 1 250 ? 19.854  -25.840 38.759  1.00 35.90  ? 250 SER B CA  1 
ATOM   4121  C  C   . SER B 1 250 ? 20.549  -25.862 40.126  1.00 35.31  ? 250 SER B C   1 
ATOM   4122  O  O   . SER B 1 250 ? 21.308  -26.785 40.441  1.00 32.84  ? 250 SER B O   1 
ATOM   4123  C  CB  . SER B 1 250 ? 18.811  -26.925 38.582  1.00 38.23  ? 250 SER B CB  1 
ATOM   4124  O  OG  . SER B 1 250 ? 18.343  -27.399 39.826  1.00 44.19  ? 250 SER B OG  1 
ATOM   4125  N  N   . VAL B 1 251 ? 20.319  -24.818 40.929  1.00 33.06  ? 251 VAL B N   1 
ATOM   4126  C  CA  . VAL B 1 251 ? 20.993  -24.662 42.210  1.00 33.80  ? 251 VAL B CA  1 
ATOM   4127  C  C   . VAL B 1 251 ? 20.471  -25.692 43.221  1.00 36.48  ? 251 VAL B C   1 
ATOM   4128  O  O   . VAL B 1 251 ? 21.237  -26.272 43.988  1.00 39.30  ? 251 VAL B O   1 
ATOM   4129  C  CB  . VAL B 1 251 ? 20.714  -23.192 42.575  1.00 37.74  ? 251 VAL B CB  1 
ATOM   4130  C  CG1 . VAL B 1 251 ? 20.495  -22.968 44.039  1.00 45.18  ? 251 VAL B CG1 1 
ATOM   4131  C  CG2 . VAL B 1 251 ? 21.793  -22.258 42.071  1.00 43.03  ? 251 VAL B CG2 1 
ATOM   4132  N  N   . GLY B 1 252 ? 19.153  -25.938 43.181  1.00 35.69  ? 252 GLY B N   1 
ATOM   4133  C  CA  . GLY B 1 252 ? 18.474  -26.847 44.081  1.00 37.24  ? 252 GLY B CA  1 
ATOM   4134  C  C   . GLY B 1 252 ? 18.963  -28.283 43.932  1.00 38.50  ? 252 GLY B C   1 
ATOM   4135  O  O   . GLY B 1 252 ? 19.120  -29.004 44.902  1.00 38.92  ? 252 GLY B O   1 
ATOM   4136  N  N   . ARG B 1 253 ? 19.241  -28.704 42.710  1.00 39.14  ? 253 ARG B N   1 
ATOM   4137  C  CA  . ARG B 1 253 ? 19.666  -30.076 42.469  1.00 44.25  ? 253 ARG B CA  1 
ATOM   4138  C  C   . ARG B 1 253 ? 21.176  -30.180 42.318  1.00 42.51  ? 253 ARG B C   1 
ATOM   4139  O  O   . ARG B 1 253 ? 21.675  -31.223 41.939  1.00 36.03  ? 253 ARG B O   1 
ATOM   4140  C  CB  . ARG B 1 253 ? 18.974  -30.581 41.209  1.00 46.27  ? 253 ARG B CB  1 
ATOM   4141  C  CG  . ARG B 1 253 ? 17.464  -30.565 41.394  1.00 57.73  ? 253 ARG B CG  1 
ATOM   4142  C  CD  . ARG B 1 253 ? 16.847  -31.695 40.605  1.00 72.00  ? 253 ARG B CD  1 
ATOM   4143  N  NE  . ARG B 1 253 ? 17.468  -31.681 39.276  1.00 76.97  ? 253 ARG B NE  1 
ATOM   4144  C  CZ  . ARG B 1 253 ? 17.357  -30.693 38.394  1.00 81.14  ? 253 ARG B CZ  1 
ATOM   4145  N  NH1 . ARG B 1 253 ? 16.366  -29.804 38.482  1.00 76.53  ? 253 ARG B NH1 1 
ATOM   4146  N  NH2 . ARG B 1 253 ? 18.222  -30.648 37.397  1.00 83.25  ? 253 ARG B NH2 1 
ATOM   4147  N  N   . GLU B 1 254 ? 21.901  -29.101 42.648  1.00 48.67  ? 254 GLU B N   1 
ATOM   4148  C  CA  . GLU B 1 254 ? 23.352  -29.031 42.512  1.00 49.66  ? 254 GLU B CA  1 
ATOM   4149  C  C   . GLU B 1 254 ? 23.813  -29.501 41.127  1.00 47.45  ? 254 GLU B C   1 
ATOM   4150  O  O   . GLU B 1 254 ? 24.793  -30.223 41.041  1.00 37.35  ? 254 GLU B O   1 
ATOM   4151  C  CB  . GLU B 1 254 ? 24.030  -29.853 43.597  1.00 52.59  ? 254 GLU B CB  1 
ATOM   4152  C  CG  . GLU B 1 254 ? 23.673  -29.397 45.012  1.00 64.49  ? 254 GLU B CG  1 
ATOM   4153  C  CD  . GLU B 1 254 ? 24.372  -30.151 46.130  1.00 69.81  ? 254 GLU B CD  1 
ATOM   4154  O  OE1 . GLU B 1 254 ? 25.611  -30.021 46.042  1.00 77.16  ? 254 GLU B OE1 1 
ATOM   4155  O  OE2 . GLU B 1 254 ? 23.770  -30.811 47.036  1.00 61.46  ? 254 GLU B OE2 1 
ATOM   4156  N  N   . GLU B 1 255 ? 23.120  -29.096 40.040  1.00 40.32  ? 255 GLU B N   1 
ATOM   4157  C  CA  . GLU B 1 255 ? 23.614  -29.330 38.697  1.00 33.34  ? 255 GLU B CA  1 
ATOM   4158  C  C   . GLU B 1 255 ? 24.245  -28.077 38.110  1.00 28.47  ? 255 GLU B C   1 
ATOM   4159  O  O   . GLU B 1 255 ? 23.586  -27.056 37.989  1.00 27.68  ? 255 GLU B O   1 
ATOM   4160  C  CB  . GLU B 1 255 ? 22.502  -29.710 37.753  1.00 36.80  ? 255 GLU B CB  1 
ATOM   4161  C  CG  . GLU B 1 255 ? 22.041  -31.137 37.980  1.00 46.16  ? 255 GLU B CG  1 
ATOM   4162  C  CD  . GLU B 1 255 ? 21.073  -31.512 36.875  1.00 58.55  ? 255 GLU B CD  1 
ATOM   4163  O  OE1 . GLU B 1 255 ? 20.865  -30.679 35.912  1.00 54.13  ? 255 GLU B OE1 1 
ATOM   4164  O  OE2 . GLU B 1 255 ? 20.595  -32.679 36.991  1.00 64.02  ? 255 GLU B OE2 1 
ATOM   4165  N  N   . PHE B 1 256 ? 25.528  -28.156 37.782  1.00 26.64  ? 256 PHE B N   1 
ATOM   4166  C  CA  . PHE B 1 256 ? 26.221  -27.066 37.124  1.00 28.53  ? 256 PHE B CA  1 
ATOM   4167  C  C   . PHE B 1 256 ? 26.888  -27.638 35.877  1.00 30.72  ? 256 PHE B C   1 
ATOM   4168  O  O   . PHE B 1 256 ? 27.656  -28.584 35.967  1.00 30.52  ? 256 PHE B O   1 
ATOM   4169  C  CB  . PHE B 1 256 ? 27.235  -26.434 38.062  1.00 30.10  ? 256 PHE B CB  1 
ATOM   4170  C  CG  . PHE B 1 256 ? 26.639  -26.037 39.399  1.00 31.77  ? 256 PHE B CG  1 
ATOM   4171  C  CD1 . PHE B 1 256 ? 25.983  -24.826 39.525  1.00 36.34  ? 256 PHE B CD1 1 
ATOM   4172  C  CD2 . PHE B 1 256 ? 26.738  -26.861 40.519  1.00 34.10  ? 256 PHE B CD2 1 
ATOM   4173  C  CE1 . PHE B 1 256 ? 25.500  -24.409 40.751  1.00 37.98  ? 256 PHE B CE1 1 
ATOM   4174  C  CE2 . PHE B 1 256 ? 26.207  -26.462 41.724  1.00 36.14  ? 256 PHE B CE2 1 
ATOM   4175  C  CZ  . PHE B 1 256 ? 25.622  -25.232 41.846  1.00 41.27  ? 256 PHE B CZ  1 
ATOM   4176  N  N   . GLY B 1 257 ? 26.546  -27.102 34.705  1.00 31.31  ? 257 GLY B N   1 
ATOM   4177  C  CA  . GLY B 1 257 ? 26.823  -27.821 33.481  1.00 30.90  ? 257 GLY B CA  1 
ATOM   4178  C  C   . GLY B 1 257 ? 27.371  -26.894 32.403  1.00 28.75  ? 257 GLY B C   1 
ATOM   4179  O  O   . GLY B 1 257 ? 27.244  -25.681 32.482  1.00 24.94  ? 257 GLY B O   1 
ATOM   4180  N  N   . THR B 1 258 ? 28.021  -27.498 31.408  1.00 28.88  ? 258 THR B N   1 
ATOM   4181  C  CA  . THR B 1 258 ? 28.365  -26.820 30.177  1.00 26.80  ? 258 THR B CA  1 
ATOM   4182  C  C   . THR B 1 258 ? 27.729  -27.644 29.068  1.00 24.66  ? 258 THR B C   1 
ATOM   4183  O  O   . THR B 1 258 ? 27.916  -28.837 29.031  1.00 28.46  ? 258 THR B O   1 
ATOM   4184  C  CB  . THR B 1 258 ? 29.877  -26.685 30.031  1.00 25.82  ? 258 THR B CB  1 
ATOM   4185  O  OG1 . THR B 1 258 ? 30.332  -25.691 30.954  1.00 30.70  ? 258 THR B OG1 1 
ATOM   4186  C  CG2 . THR B 1 258 ? 30.227  -26.262 28.620  1.00 29.68  ? 258 THR B CG2 1 
ATOM   4187  N  N   . TYR B 1 259 ? 26.907  -27.033 28.229  1.00 23.30  ? 259 TYR B N   1 
ATOM   4188  C  CA  . TYR B 1 259 ? 26.406  -27.700 27.042  1.00 24.79  ? 259 TYR B CA  1 
ATOM   4189  C  C   . TYR B 1 259 ? 27.367  -27.387 25.888  1.00 26.00  ? 259 TYR B C   1 
ATOM   4190  O  O   . TYR B 1 259 ? 27.453  -26.252 25.428  1.00 25.98  ? 259 TYR B O   1 
ATOM   4191  C  CB  . TYR B 1 259 ? 24.947  -27.324 26.748  1.00 25.12  ? 259 TYR B CB  1 
ATOM   4192  C  CG  . TYR B 1 259 ? 24.222  -28.317 25.846  1.00 27.77  ? 259 TYR B CG  1 
ATOM   4193  C  CD1 . TYR B 1 259 ? 24.358  -28.264 24.464  1.00 29.49  ? 259 TYR B CD1 1 
ATOM   4194  C  CD2 . TYR B 1 259 ? 23.382  -29.281 26.380  1.00 30.64  ? 259 TYR B CD2 1 
ATOM   4195  C  CE1 . TYR B 1 259 ? 23.695  -29.159 23.644  1.00 29.33  ? 259 TYR B CE1 1 
ATOM   4196  C  CE2 . TYR B 1 259 ? 22.709  -30.176 25.564  1.00 33.09  ? 259 TYR B CE2 1 
ATOM   4197  C  CZ  . TYR B 1 259 ? 22.881  -30.125 24.192  1.00 30.93  ? 259 TYR B CZ  1 
ATOM   4198  O  OH  . TYR B 1 259 ? 22.253  -31.033 23.396  1.00 29.61  ? 259 TYR B OH  1 
ATOM   4199  N  N   . PHE B 1 260 ? 28.130  -28.396 25.457  1.00 27.01  ? 260 PHE B N   1 
ATOM   4200  C  CA  . PHE B 1 260 ? 29.061  -28.271 24.352  1.00 25.81  ? 260 PHE B CA  1 
ATOM   4201  C  C   . PHE B 1 260 ? 28.342  -28.459 23.022  1.00 24.10  ? 260 PHE B C   1 
ATOM   4202  O  O   . PHE B 1 260 ? 27.643  -29.446 22.836  1.00 20.20  ? 260 PHE B O   1 
ATOM   4203  C  CB  . PHE B 1 260 ? 30.126  -29.355 24.449  1.00 27.48  ? 260 PHE B CB  1 
ATOM   4204  C  CG  . PHE B 1 260 ? 31.003  -29.391 23.215  1.00 26.98  ? 260 PHE B CG  1 
ATOM   4205  C  CD1 . PHE B 1 260 ? 32.046  -28.479 23.060  1.00 28.56  ? 260 PHE B CD1 1 
ATOM   4206  C  CD2 . PHE B 1 260 ? 30.775  -30.321 22.206  1.00 29.34  ? 260 PHE B CD2 1 
ATOM   4207  C  CE1 . PHE B 1 260 ? 32.870  -28.524 21.933  1.00 27.81  ? 260 PHE B CE1 1 
ATOM   4208  C  CE2 . PHE B 1 260 ? 31.562  -30.329 21.054  1.00 27.05  ? 260 PHE B CE2 1 
ATOM   4209  C  CZ  . PHE B 1 260 ? 32.596  -29.420 20.908  1.00 27.53  ? 260 PHE B CZ  1 
ATOM   4210  N  N   . ILE B 1 261 ? 28.538  -27.514 22.095  1.00 24.29  ? 261 ILE B N   1 
ATOM   4211  C  CA  . ILE B 1 261 ? 28.141  -27.724 20.710  1.00 26.17  ? 261 ILE B CA  1 
ATOM   4212  C  C   . ILE B 1 261 ? 29.277  -27.227 19.821  1.00 27.52  ? 261 ILE B C   1 
ATOM   4213  O  O   . ILE B 1 261 ? 29.797  -26.122 20.013  1.00 27.11  ? 261 ILE B O   1 
ATOM   4214  C  CB  . ILE B 1 261 ? 26.788  -27.070 20.356  1.00 28.90  ? 261 ILE B CB  1 
ATOM   4215  C  CG1 . ILE B 1 261 ? 26.359  -27.437 18.950  1.00 29.05  ? 261 ILE B CG1 1 
ATOM   4216  C  CG2 . ILE B 1 261 ? 26.789  -25.547 20.536  1.00 27.84  ? 261 ILE B CG2 1 
ATOM   4217  C  CD1 . ILE B 1 261 ? 24.901  -27.108 18.668  1.00 32.11  ? 261 ILE B CD1 1 
ATOM   4218  N  N   . GLY B 1 262 ? 29.709  -28.101 18.916  1.00 27.33  ? 262 GLY B N   1 
ATOM   4219  C  CA  . GLY B 1 262 ? 30.766  -27.777 17.990  1.00 29.19  ? 262 GLY B CA  1 
ATOM   4220  C  C   . GLY B 1 262 ? 30.355  -28.078 16.553  1.00 31.44  ? 262 GLY B C   1 
ATOM   4221  O  O   . GLY B 1 262 ? 29.973  -29.206 16.222  1.00 32.84  ? 262 GLY B O   1 
ATOM   4222  N  N   . TYR B 1 263 ? 30.537  -27.061 15.702  1.00 32.20  ? 263 TYR B N   1 
ATOM   4223  C  CA  . TYR B 1 263 ? 30.286  -27.174 14.279  1.00 32.49  ? 263 TYR B CA  1 
ATOM   4224  C  C   . TYR B 1 263 ? 31.588  -27.243 13.490  1.00 30.41  ? 263 TYR B C   1 
ATOM   4225  O  O   . TYR B 1 263 ? 32.557  -26.571 13.832  1.00 29.27  ? 263 TYR B O   1 
ATOM   4226  C  CB  . TYR B 1 263 ? 29.517  -25.934 13.839  1.00 28.65  ? 263 TYR B CB  1 
ATOM   4227  C  CG  . TYR B 1 263 ? 28.081  -25.820 14.321  1.00 24.97  ? 263 TYR B CG  1 
ATOM   4228  C  CD1 . TYR B 1 263 ? 27.034  -26.367 13.594  1.00 23.90  ? 263 TYR B CD1 1 
ATOM   4229  C  CD2 . TYR B 1 263 ? 27.778  -25.095 15.456  1.00 23.10  ? 263 TYR B CD2 1 
ATOM   4230  C  CE1 . TYR B 1 263 ? 25.726  -26.216 13.988  1.00 25.84  ? 263 TYR B CE1 1 
ATOM   4231  C  CE2 . TYR B 1 263 ? 26.470  -24.942 15.871  1.00 25.68  ? 263 TYR B CE2 1 
ATOM   4232  C  CZ  . TYR B 1 263 ? 25.432  -25.511 15.143  1.00 28.16  ? 263 TYR B CZ  1 
ATOM   4233  O  OH  . TYR B 1 263 ? 24.123  -25.369 15.559  1.00 25.75  ? 263 TYR B OH  1 
ATOM   4234  N  N   . ALA B 1 264 ? 31.563  -28.041 12.417  1.00 32.04  ? 264 ALA B N   1 
ATOM   4235  C  CA  . ALA B 1 264 ? 32.718  -28.268 11.557  1.00 35.96  ? 264 ALA B CA  1 
ATOM   4236  C  C   . ALA B 1 264 ? 32.251  -28.755 10.184  1.00 32.99  ? 264 ALA B C   1 
ATOM   4237  O  O   . ALA B 1 264 ? 31.191  -29.391 10.121  1.00 32.98  ? 264 ALA B O   1 
ATOM   4238  C  CB  . ALA B 1 264 ? 33.586  -29.320 12.226  1.00 39.36  ? 264 ALA B CB  1 
ATOM   4239  N  N   . ARG B 1 265 ? 33.045  -28.506 9.122   1.00 29.49  ? 265 ARG B N   1 
ATOM   4240  C  CA  . ARG B 1 265 ? 32.669  -28.891 7.761   1.00 34.89  ? 265 ARG B CA  1 
ATOM   4241  C  C   . ARG B 1 265 ? 32.737  -30.413 7.552   1.00 33.66  ? 265 ARG B C   1 
ATOM   4242  O  O   . ARG B 1 265 ? 32.146  -30.932 6.612   1.00 29.88  ? 265 ARG B O   1 
ATOM   4243  C  CB  . ARG B 1 265 ? 33.501  -28.189 6.674   1.00 42.07  ? 265 ARG B CB  1 
ATOM   4244  C  CG  . ARG B 1 265 ? 34.921  -28.692 6.545   1.00 55.14  ? 265 ARG B CG  1 
ATOM   4245  C  CD  . ARG B 1 265 ? 35.769  -27.872 5.594   1.00 66.17  ? 265 ARG B CD  1 
ATOM   4246  N  NE  . ARG B 1 265 ? 35.185  -27.958 4.246   1.00 83.27  ? 265 ARG B NE  1 
ATOM   4247  C  CZ  . ARG B 1 265 ? 35.169  -27.003 3.312   1.00 74.37  ? 265 ARG B CZ  1 
ATOM   4248  N  NH1 . ARG B 1 265 ? 35.713  -25.804 3.507   1.00 60.70  ? 265 ARG B NH1 1 
ATOM   4249  N  NH2 . ARG B 1 265 ? 34.596  -27.238 2.151   1.00 71.35  ? 265 ARG B NH2 1 
ATOM   4250  N  N   . THR B 1 266 ? 33.469  -31.123 8.420   1.00 33.83  ? 266 THR B N   1 
ATOM   4251  C  CA  . THR B 1 266 ? 33.467  -32.584 8.473   1.00 33.07  ? 266 THR B CA  1 
ATOM   4252  C  C   . THR B 1 266 ? 33.563  -33.005 9.944   1.00 33.11  ? 266 THR B C   1 
ATOM   4253  O  O   . THR B 1 266 ? 34.299  -32.412 10.744  1.00 34.49  ? 266 THR B O   1 
ATOM   4254  C  CB  . THR B 1 266 ? 34.634  -33.177 7.674   1.00 32.73  ? 266 THR B CB  1 
ATOM   4255  O  OG1 . THR B 1 266 ? 34.801  -34.543 8.068   1.00 35.94  ? 266 THR B OG1 1 
ATOM   4256  C  CG2 . THR B 1 266 ? 35.975  -32.533 7.990   1.00 32.57  ? 266 THR B CG2 1 
ATOM   4257  N  N   . PRO B 1 267 ? 32.898  -34.091 10.357  1.00 30.87  ? 267 PRO B N   1 
ATOM   4258  C  CA  . PRO B 1 267 ? 33.028  -34.542 11.736  1.00 33.20  ? 267 PRO B CA  1 
ATOM   4259  C  C   . PRO B 1 267 ? 34.410  -35.072 12.097  1.00 33.71  ? 267 PRO B C   1 
ATOM   4260  O  O   . PRO B 1 267 ? 34.701  -35.209 13.281  1.00 36.44  ? 267 PRO B O   1 
ATOM   4261  C  CB  . PRO B 1 267 ? 31.947  -35.596 11.872  1.00 31.81  ? 267 PRO B CB  1 
ATOM   4262  C  CG  . PRO B 1 267 ? 31.697  -36.064 10.475  1.00 31.41  ? 267 PRO B CG  1 
ATOM   4263  C  CD  . PRO B 1 267 ? 32.001  -34.911 9.541   1.00 32.27  ? 267 PRO B CD  1 
ATOM   4264  N  N   . GLU B 1 268 ? 35.261  -35.348 11.095  1.00 39.36  ? 268 GLU B N   1 
ATOM   4265  C  CA  . GLU B 1 268 ? 36.547  -35.998 11.371  1.00 42.21  ? 268 GLU B CA  1 
ATOM   4266  C  C   . GLU B 1 268 ? 37.358  -35.072 12.295  1.00 36.36  ? 268 GLU B C   1 
ATOM   4267  O  O   . GLU B 1 268 ? 38.044  -35.508 13.208  1.00 34.52  ? 268 GLU B O   1 
ATOM   4268  C  CB  . GLU B 1 268 ? 37.244  -36.535 10.105  1.00 42.14  ? 268 GLU B CB  1 
ATOM   4269  C  CG  . GLU B 1 268 ? 37.891  -37.919 10.295  1.00 38.38  ? 268 GLU B CG  1 
ATOM   4270  N  N   . VAL B 1 269 ? 37.201  -33.755 12.123  1.00 34.35  ? 269 VAL B N   1 
ATOM   4271  C  CA  . VAL B 1 269 ? 37.962  -32.811 12.930  1.00 35.65  ? 269 VAL B CA  1 
ATOM   4272  C  C   . VAL B 1 269 ? 37.506  -32.883 14.385  1.00 36.02  ? 269 VAL B C   1 
ATOM   4273  O  O   . VAL B 1 269 ? 38.338  -33.027 15.281  1.00 33.71  ? 269 VAL B O   1 
ATOM   4274  C  CB  . VAL B 1 269 ? 37.810  -31.386 12.361  1.00 37.98  ? 269 VAL B CB  1 
ATOM   4275  C  CG1 . VAL B 1 269 ? 38.482  -30.322 13.234  1.00 30.30  ? 269 VAL B CG1 1 
ATOM   4276  C  CG2 . VAL B 1 269 ? 38.324  -31.339 10.918  1.00 42.25  ? 269 VAL B CG2 1 
ATOM   4277  N  N   . THR B 1 270 ? 36.186  -32.754 14.599  1.00 37.33  ? 270 THR B N   1 
ATOM   4278  C  CA  . THR B 1 270 ? 35.618  -32.766 15.940  1.00 35.59  ? 270 THR B CA  1 
ATOM   4279  C  C   . THR B 1 270 ? 35.961  -34.101 16.627  1.00 39.00  ? 270 THR B C   1 
ATOM   4280  O  O   . THR B 1 270 ? 36.314  -34.122 17.817  1.00 34.64  ? 270 THR B O   1 
ATOM   4281  C  CB  . THR B 1 270 ? 34.115  -32.525 15.885  1.00 30.71  ? 270 THR B CB  1 
ATOM   4282  O  OG1 . THR B 1 270 ? 33.767  -31.364 15.151  1.00 31.98  ? 270 THR B OG1 1 
ATOM   4283  C  CG2 . THR B 1 270 ? 33.549  -32.298 17.269  1.00 31.90  ? 270 THR B CG2 1 
ATOM   4284  N  N   . GLU B 1 271 ? 35.876  -35.209 15.862  1.00 38.27  ? 271 GLU B N   1 
ATOM   4285  C  CA  . GLU B 1 271 ? 36.074  -36.547 16.409  1.00 32.96  ? 271 GLU B CA  1 
ATOM   4286  C  C   . GLU B 1 271 ? 37.539  -36.741 16.810  1.00 36.36  ? 271 GLU B C   1 
ATOM   4287  O  O   . GLU B 1 271 ? 37.842  -37.453 17.765  1.00 35.06  ? 271 GLU B O   1 
ATOM   4288  C  CB  . GLU B 1 271 ? 35.657  -37.644 15.429  1.00 30.19  ? 271 GLU B CB  1 
ATOM   4289  C  CG  . GLU B 1 271 ? 34.153  -37.782 15.295  1.00 32.05  ? 271 GLU B CG  1 
ATOM   4290  C  CD  . GLU B 1 271 ? 33.651  -38.793 14.308  1.00 38.33  ? 271 GLU B CD  1 
ATOM   4291  O  OE1 . GLU B 1 271 ? 34.284  -39.850 14.097  1.00 54.14  ? 271 GLU B OE1 1 
ATOM   4292  O  OE2 . GLU B 1 271 ? 32.505  -38.584 13.912  1.00 38.83  ? 271 GLU B OE2 1 
ATOM   4293  N  N   . THR B 1 272 ? 38.469  -36.119 16.070  1.00 35.04  ? 272 THR B N   1 
ATOM   4294  C  CA  . THR B 1 272 ? 39.876  -36.262 16.408  1.00 31.81  ? 272 THR B CA  1 
ATOM   4295  C  C   . THR B 1 272 ? 40.136  -35.597 17.743  1.00 33.42  ? 272 THR B C   1 
ATOM   4296  O  O   . THR B 1 272 ? 40.855  -36.148 18.577  1.00 36.85  ? 272 THR B O   1 
ATOM   4297  C  CB  . THR B 1 272 ? 40.720  -35.636 15.304  1.00 32.50  ? 272 THR B CB  1 
ATOM   4298  O  OG1 . THR B 1 272 ? 40.522  -36.509 14.189  1.00 34.05  ? 272 THR B OG1 1 
ATOM   4299  C  CG2 . THR B 1 272 ? 42.191  -35.458 15.630  1.00 30.69  ? 272 THR B CG2 1 
ATOM   4300  N  N   . MET B 1 273 ? 39.594  -34.385 17.914  1.00 35.47  ? 273 MET B N   1 
ATOM   4301  C  CA  . MET B 1 273 ? 39.807  -33.636 19.144  1.00 33.29  ? 273 MET B CA  1 
ATOM   4302  C  C   . MET B 1 273 ? 39.239  -34.454 20.304  1.00 33.48  ? 273 MET B C   1 
ATOM   4303  O  O   . MET B 1 273 ? 39.829  -34.546 21.372  1.00 35.77  ? 273 MET B O   1 
ATOM   4304  C  CB  . MET B 1 273 ? 39.111  -32.275 19.061  1.00 38.87  ? 273 MET B CB  1 
ATOM   4305  C  CG  . MET B 1 273 ? 39.715  -31.279 18.068  1.00 38.59  ? 273 MET B CG  1 
ATOM   4306  S  SD  . MET B 1 273 ? 38.646  -29.824 17.925  1.00 35.77  ? 273 MET B SD  1 
ATOM   4307  C  CE  . MET B 1 273 ? 39.564  -28.768 16.818  1.00 35.32  ? 273 MET B CE  1 
ATOM   4308  N  N   . LEU B 1 274 ? 38.091  -35.091 20.083  1.00 33.21  ? 274 LEU B N   1 
ATOM   4309  C  CA  . LEU B 1 274 ? 37.500  -35.919 21.121  1.00 34.39  ? 274 LEU B CA  1 
ATOM   4310  C  C   . LEU B 1 274 ? 38.373  -37.121 21.491  1.00 32.43  ? 274 LEU B C   1 
ATOM   4311  O  O   . LEU B 1 274 ? 38.459  -37.466 22.664  1.00 29.89  ? 274 LEU B O   1 
ATOM   4312  C  CB  . LEU B 1 274 ? 36.112  -36.363 20.668  1.00 35.89  ? 274 LEU B CB  1 
ATOM   4313  C  CG  . LEU B 1 274 ? 34.976  -35.358 20.889  1.00 33.63  ? 274 LEU B CG  1 
ATOM   4314  C  CD1 . LEU B 1 274 ? 33.689  -35.885 20.232  1.00 33.91  ? 274 LEU B CD1 1 
ATOM   4315  C  CD2 . LEU B 1 274 ? 34.768  -35.093 22.387  1.00 33.92  ? 274 LEU B CD2 1 
ATOM   4316  N  N   . GLU B 1 275 ? 38.984  -37.781 20.501  1.00 34.18  ? 275 GLU B N   1 
ATOM   4317  C  CA  . GLU B 1 275 ? 39.847  -38.928 20.760  1.00 36.72  ? 275 GLU B CA  1 
ATOM   4318  C  C   . GLU B 1 275 ? 41.068  -38.486 21.567  1.00 32.65  ? 275 GLU B C   1 
ATOM   4319  O  O   . GLU B 1 275 ? 41.472  -39.138 22.533  1.00 31.70  ? 275 GLU B O   1 
ATOM   4320  C  CB  . GLU B 1 275 ? 40.413  -39.600 19.516  1.00 36.97  ? 275 GLU B CB  1 
ATOM   4321  C  CG  . GLU B 1 275 ? 39.424  -40.420 18.695  1.00 43.75  ? 275 GLU B CG  1 
ATOM   4322  C  CD  . GLU B 1 275 ? 40.101  -40.910 17.401  1.00 51.43  ? 275 GLU B CD  1 
ATOM   4323  O  OE1 . GLU B 1 275 ? 41.336  -41.198 17.420  1.00 58.00  ? 275 GLU B OE1 1 
ATOM   4324  O  OE2 . GLU B 1 275 ? 39.427  -41.010 16.346  1.00 56.63  ? 275 GLU B OE2 1 
ATOM   4325  N  N   . ARG B 1 276 ? 41.628  -37.344 21.206  1.00 29.72  ? 276 ARG B N   1 
ATOM   4326  C  CA  . ARG B 1 276 ? 42.741  -36.824 21.967  1.00 34.04  ? 276 ARG B CA  1 
ATOM   4327  C  C   . ARG B 1 276 ? 42.350  -36.523 23.405  1.00 35.45  ? 276 ARG B C   1 
ATOM   4328  O  O   . ARG B 1 276 ? 43.146  -36.747 24.304  1.00 41.30  ? 276 ARG B O   1 
ATOM   4329  C  CB  . ARG B 1 276 ? 43.295  -35.582 21.283  1.00 38.11  ? 276 ARG B CB  1 
ATOM   4330  C  CG  . ARG B 1 276 ? 44.111  -36.072 20.099  1.00 40.69  ? 276 ARG B CG  1 
ATOM   4331  C  CD  . ARG B 1 276 ? 44.188  -35.053 19.021  1.00 47.69  ? 276 ARG B CD  1 
ATOM   4332  N  NE  . ARG B 1 276 ? 44.896  -33.856 19.501  1.00 60.01  ? 276 ARG B NE  1 
ATOM   4333  C  CZ  . ARG B 1 276 ? 46.209  -33.727 19.697  1.00 67.58  ? 276 ARG B CZ  1 
ATOM   4334  N  NH1 . ARG B 1 276 ? 47.045  -34.735 19.501  1.00 78.31  ? 276 ARG B NH1 1 
ATOM   4335  N  NH2 . ARG B 1 276 ? 46.682  -32.585 20.130  1.00 60.65  ? 276 ARG B NH2 1 
ATOM   4336  N  N   . MET B 1 277 ? 41.139  -36.006 23.620  1.00 38.41  ? 277 MET B N   1 
ATOM   4337  C  CA  . MET B 1 277 ? 40.716  -35.641 24.965  1.00 37.76  ? 277 MET B CA  1 
ATOM   4338  C  C   . MET B 1 277 ? 40.450  -36.903 25.788  1.00 31.50  ? 277 MET B C   1 
ATOM   4339  O  O   . MET B 1 277 ? 40.824  -36.967 26.946  1.00 26.84  ? 277 MET B O   1 
ATOM   4340  C  CB  . MET B 1 277 ? 39.453  -34.766 24.941  1.00 36.84  ? 277 MET B CB  1 
ATOM   4341  C  CG  . MET B 1 277 ? 39.652  -33.331 24.445  1.00 33.00  ? 277 MET B CG  1 
ATOM   4342  S  SD  . MET B 1 277 ? 38.022  -32.544 24.309  1.00 33.81  ? 277 MET B SD  1 
ATOM   4343  C  CE  . MET B 1 277 ? 37.380  -32.554 25.988  1.00 27.80  ? 277 MET B CE  1 
ATOM   4344  N  N   . PHE B 1 278 ? 39.779  -37.896 25.198  1.00 30.40  ? 278 PHE B N   1 
ATOM   4345  C  CA  . PHE B 1 278 ? 39.276  -39.010 25.981  1.00 32.35  ? 278 PHE B CA  1 
ATOM   4346  C  C   . PHE B 1 278 ? 40.287  -40.155 26.049  1.00 40.93  ? 278 PHE B C   1 
ATOM   4347  O  O   . PHE B 1 278 ? 40.335  -40.885 27.057  1.00 40.70  ? 278 PHE B O   1 
ATOM   4348  C  CB  . PHE B 1 278 ? 37.939  -39.484 25.418  1.00 29.57  ? 278 PHE B CB  1 
ATOM   4349  C  CG  . PHE B 1 278 ? 36.785  -38.649 25.928  1.00 29.25  ? 278 PHE B CG  1 
ATOM   4350  C  CD1 . PHE B 1 278 ? 36.420  -37.467 25.289  1.00 31.35  ? 278 PHE B CD1 1 
ATOM   4351  C  CD2 . PHE B 1 278 ? 36.115  -39.013 27.075  1.00 28.79  ? 278 PHE B CD2 1 
ATOM   4352  C  CE1 . PHE B 1 278 ? 35.410  -36.668 25.789  1.00 32.33  ? 278 PHE B CE1 1 
ATOM   4353  C  CE2 . PHE B 1 278 ? 35.086  -38.219 27.560  1.00 31.73  ? 278 PHE B CE2 1 
ATOM   4354  C  CZ  . PHE B 1 278 ? 34.730  -37.053 26.919  1.00 32.96  ? 278 PHE B CZ  1 
ATOM   4355  N  N   . LEU B 1 279 ? 41.038  -40.347 24.952  1.00 39.45  ? 279 LEU B N   1 
ATOM   4356  C  CA  . LEU B 1 279 ? 41.905  -41.513 24.819  1.00 39.63  ? 279 LEU B CA  1 
ATOM   4357  C  C   . LEU B 1 279 ? 43.354  -41.126 25.039  1.00 41.41  ? 279 LEU B C   1 
ATOM   4358  O  O   . LEU B 1 279 ? 44.172  -41.974 25.349  1.00 54.49  ? 279 LEU B O   1 
ATOM   4359  C  CB  . LEU B 1 279 ? 41.751  -42.166 23.454  1.00 37.80  ? 279 LEU B CB  1 
ATOM   4360  C  CG  . LEU B 1 279 ? 40.334  -42.612 23.086  1.00 41.07  ? 279 LEU B CG  1 
ATOM   4361  C  CD1 . LEU B 1 279 ? 40.397  -43.227 21.701  1.00 40.06  ? 279 LEU B CD1 1 
ATOM   4362  C  CD2 . LEU B 1 279 ? 39.732  -43.571 24.102  1.00 43.10  ? 279 LEU B CD2 1 
ATOM   4363  N  N   . GLY B 1 280 ? 43.676  -39.853 24.884  1.00 40.14  ? 280 GLY B N   1 
ATOM   4364  C  CA  . GLY B 1 280 ? 45.014  -39.413 25.213  1.00 42.69  ? 280 GLY B CA  1 
ATOM   4365  C  C   . GLY B 1 280 ? 45.927  -39.502 24.007  1.00 41.66  ? 280 GLY B C   1 
ATOM   4366  O  O   . GLY B 1 280 ? 45.496  -39.869 22.938  1.00 53.42  ? 280 GLY B O   1 
ATOM   4367  N  N   . THR B 1 281 ? 47.169  -39.081 24.218  1.00 41.49  ? 281 THR B N   1 
ATOM   4368  C  CA  . THR B 1 281 ? 48.247  -39.108 23.246  1.00 43.84  ? 281 THR B CA  1 
ATOM   4369  C  C   . THR B 1 281 ? 49.448  -39.793 23.896  1.00 44.41  ? 281 THR B C   1 
ATOM   4370  O  O   . THR B 1 281 ? 49.351  -40.316 24.999  1.00 39.88  ? 281 THR B O   1 
ATOM   4371  C  CB  . THR B 1 281 ? 48.582  -37.673 22.835  1.00 46.41  ? 281 THR B CB  1 
ATOM   4372  O  OG1 . THR B 1 281 ? 49.155  -36.966 23.936  1.00 47.21  ? 281 THR B OG1 1 
ATOM   4373  C  CG2 . THR B 1 281 ? 47.350  -36.945 22.327  1.00 44.87  ? 281 THR B CG2 1 
ATOM   4374  N  N   . ALA B 1 282 ? 50.593  -39.787 23.229  1.00 49.91  ? 282 ALA B N   1 
ATOM   4375  C  CA  . ALA B 1 282 ? 51.801  -40.292 23.865  1.00 52.48  ? 282 ALA B CA  1 
ATOM   4376  C  C   . ALA B 1 282 ? 52.080  -39.474 25.120  1.00 55.97  ? 282 ALA B C   1 
ATOM   4377  O  O   . ALA B 1 282 ? 52.335  -39.999 26.194  1.00 54.76  ? 282 ALA B O   1 
ATOM   4378  C  CB  . ALA B 1 282 ? 52.966  -40.223 22.907  1.00 61.56  ? 282 ALA B CB  1 
ATOM   4379  N  N   . SER B 1 283 ? 51.950  -38.153 24.992  1.00 58.34  ? 283 SER B N   1 
ATOM   4380  C  CA  . SER B 1 283 ? 52.329  -37.214 26.033  1.00 61.58  ? 283 SER B CA  1 
ATOM   4381  C  C   . SER B 1 283 ? 51.317  -37.088 27.165  1.00 65.92  ? 283 SER B C   1 
ATOM   4382  O  O   . SER B 1 283 ? 51.658  -36.537 28.200  1.00 72.39  ? 283 SER B O   1 
ATOM   4383  C  CB  . SER B 1 283 ? 52.444  -35.869 25.467  1.00 60.34  ? 283 SER B CB  1 
ATOM   4384  O  OG  . SER B 1 283 ? 53.266  -35.867 24.317  1.00 60.16  ? 283 SER B OG  1 
ATOM   4385  N  N   . ALA B 1 284 ? 50.060  -37.479 26.943  1.00 62.89  ? 284 ALA B N   1 
ATOM   4386  C  CA  . ALA B 1 284 ? 49.008  -37.074 27.852  1.00 53.57  ? 284 ALA B CA  1 
ATOM   4387  C  C   . ALA B 1 284 ? 47.997  -38.202 28.037  1.00 44.29  ? 284 ALA B C   1 
ATOM   4388  O  O   . ALA B 1 284 ? 47.367  -38.672 27.096  1.00 44.76  ? 284 ALA B O   1 
ATOM   4389  C  CB  . ALA B 1 284 ? 48.366  -35.828 27.285  1.00 53.32  ? 284 ALA B CB  1 
ATOM   4390  N  N   . PRO B 1 285 ? 47.751  -38.649 29.273  1.00 35.44  ? 285 PRO B N   1 
ATOM   4391  C  CA  . PRO B 1 285 ? 46.750  -39.706 29.472  1.00 35.94  ? 285 PRO B CA  1 
ATOM   4392  C  C   . PRO B 1 285 ? 45.355  -39.314 28.984  1.00 35.65  ? 285 PRO B C   1 
ATOM   4393  O  O   . PRO B 1 285 ? 44.639  -40.192 28.517  1.00 36.41  ? 285 PRO B O   1 
ATOM   4394  C  CB  . PRO B 1 285 ? 46.788  -39.975 30.998  1.00 34.47  ? 285 PRO B CB  1 
ATOM   4395  C  CG  . PRO B 1 285 ? 47.440  -38.711 31.562  1.00 37.92  ? 285 PRO B CG  1 
ATOM   4396  C  CD  . PRO B 1 285 ? 48.388  -38.144 30.504  1.00 32.61  ? 285 PRO B CD  1 
ATOM   4397  N  N   . HIS B 1 286 ? 44.981  -38.032 29.175  1.00 32.97  ? 286 HIS B N   1 
ATOM   4398  C  CA  . HIS B 1 286 ? 43.680  -37.504 28.811  1.00 31.21  ? 286 HIS B CA  1 
ATOM   4399  C  C   . HIS B 1 286 ? 43.639  -36.019 29.156  1.00 35.38  ? 286 HIS B C   1 
ATOM   4400  O  O   . HIS B 1 286 ? 44.522  -35.525 29.855  1.00 34.18  ? 286 HIS B O   1 
ATOM   4401  C  CB  . HIS B 1 286 ? 42.521  -38.217 29.512  1.00 34.23  ? 286 HIS B CB  1 
ATOM   4402  C  CG  . HIS B 1 286 ? 42.614  -38.203 30.997  1.00 43.07  ? 286 HIS B CG  1 
ATOM   4403  N  ND1 . HIS B 1 286 ? 43.007  -39.318 31.720  1.00 39.64  ? 286 HIS B ND1 1 
ATOM   4404  C  CD2 . HIS B 1 286 ? 42.321  -37.218 31.891  1.00 40.71  ? 286 HIS B CD2 1 
ATOM   4405  C  CE1 . HIS B 1 286 ? 42.961  -38.985 33.017  1.00 40.77  ? 286 HIS B CE1 1 
ATOM   4406  N  NE2 . HIS B 1 286 ? 42.537  -37.718 33.149  1.00 35.69  ? 286 HIS B NE2 1 
ATOM   4407  N  N   . ASP B 1 287 ? 42.587  -35.337 28.659  1.00 33.05  ? 287 ASP B N   1 
ATOM   4408  C  CA  . ASP B 1 287 ? 42.344  -33.937 28.945  1.00 30.72  ? 287 ASP B CA  1 
ATOM   4409  C  C   . ASP B 1 287 ? 41.993  -33.796 30.419  1.00 28.13  ? 287 ASP B C   1 
ATOM   4410  O  O   . ASP B 1 287 ? 41.054  -34.400 30.906  1.00 24.84  ? 287 ASP B O   1 
ATOM   4411  C  CB  . ASP B 1 287 ? 41.257  -33.411 28.021  1.00 29.57  ? 287 ASP B CB  1 
ATOM   4412  C  CG  . ASP B 1 287 ? 41.037  -31.903 28.006  1.00 29.39  ? 287 ASP B CG  1 
ATOM   4413  O  OD1 . ASP B 1 287 ? 41.405  -31.233 28.979  1.00 28.45  ? 287 ASP B OD1 1 
ATOM   4414  O  OD2 . ASP B 1 287 ? 40.529  -31.407 26.989  1.00 28.48  ? 287 ASP B OD2 1 
ATOM   4415  N  N   . ARG B 1 288 ? 42.759  -32.973 31.129  1.00 31.78  ? 288 ARG B N   1 
ATOM   4416  C  CA  . ARG B 1 288 ? 42.507  -32.699 32.537  1.00 35.71  ? 288 ARG B CA  1 
ATOM   4417  C  C   . ARG B 1 288 ? 41.118  -32.114 32.796  1.00 30.46  ? 288 ARG B C   1 
ATOM   4418  O  O   . ARG B 1 288 ? 40.609  -32.214 33.898  1.00 28.89  ? 288 ARG B O   1 
ATOM   4419  C  CB  . ARG B 1 288 ? 43.575  -31.740 33.083  1.00 41.63  ? 288 ARG B CB  1 
ATOM   4420  C  CG  . ARG B 1 288 ? 44.949  -32.376 33.218  1.00 39.46  ? 288 ARG B CG  1 
ATOM   4421  C  CD  . ARG B 1 288 ? 44.965  -33.131 34.503  1.00 40.75  ? 288 ARG B CD  1 
ATOM   4422  N  NE  . ARG B 1 288 ? 45.002  -32.224 35.667  1.00 42.29  ? 288 ARG B NE  1 
ATOM   4423  C  CZ  . ARG B 1 288 ? 44.339  -32.381 36.820  1.00 32.21  ? 288 ARG B CZ  1 
ATOM   4424  N  NH1 . ARG B 1 288 ? 43.433  -33.340 36.988  1.00 31.81  ? 288 ARG B NH1 1 
ATOM   4425  N  NH2 . ARG B 1 288 ? 44.587  -31.562 37.822  1.00 28.72  ? 288 ARG B NH2 1 
ATOM   4426  N  N   . ILE B 1 289 ? 40.501  -31.485 31.807  1.00 28.01  ? 289 ILE B N   1 
ATOM   4427  C  CA  . ILE B 1 289 ? 39.194  -30.905 32.044  1.00 28.91  ? 289 ILE B CA  1 
ATOM   4428  C  C   . ILE B 1 289 ? 38.164  -32.004 32.326  1.00 26.91  ? 289 ILE B C   1 
ATOM   4429  O  O   . ILE B 1 289 ? 37.160  -31.738 32.974  1.00 30.74  ? 289 ILE B O   1 
ATOM   4430  C  CB  . ILE B 1 289 ? 38.770  -30.008 30.876  1.00 30.00  ? 289 ILE B CB  1 
ATOM   4431  C  CG1 . ILE B 1 289 ? 37.871  -28.891 31.372  1.00 29.56  ? 289 ILE B CG1 1 
ATOM   4432  C  CG2 . ILE B 1 289 ? 38.157  -30.831 29.737  1.00 30.30  ? 289 ILE B CG2 1 
ATOM   4433  C  CD1 . ILE B 1 289 ? 37.551  -27.889 30.281  1.00 35.71  ? 289 ILE B CD1 1 
ATOM   4434  N  N   . LEU B 1 290 ? 38.420  -33.232 31.860  1.00 24.30  ? 290 LEU B N   1 
ATOM   4435  C  CA  . LEU B 1 290 ? 37.518  -34.355 32.088  1.00 24.57  ? 290 LEU B CA  1 
ATOM   4436  C  C   . LEU B 1 290 ? 37.619  -34.855 33.529  1.00 23.28  ? 290 LEU B C   1 
ATOM   4437  O  O   . LEU B 1 290 ? 36.737  -35.558 34.007  1.00 25.65  ? 290 LEU B O   1 
ATOM   4438  C  CB  . LEU B 1 290 ? 37.785  -35.478 31.091  1.00 25.12  ? 290 LEU B CB  1 
ATOM   4439  C  CG  . LEU B 1 290 ? 37.643  -35.119 29.617  1.00 27.21  ? 290 LEU B CG  1 
ATOM   4440  C  CD1 . LEU B 1 290 ? 38.033  -36.249 28.718  1.00 27.74  ? 290 LEU B CD1 1 
ATOM   4441  C  CD2 . LEU B 1 290 ? 36.223  -34.673 29.347  1.00 31.91  ? 290 LEU B CD2 1 
ATOM   4442  N  N   . ASP B 1 291 ? 38.657  -34.446 34.262  1.00 24.94  ? 291 ASP B N   1 
ATOM   4443  C  CA  . ASP B 1 291 ? 38.700  -34.776 35.673  1.00 26.40  ? 291 ASP B CA  1 
ATOM   4444  C  C   . ASP B 1 291 ? 37.707  -33.929 36.451  1.00 28.24  ? 291 ASP B C   1 
ATOM   4445  O  O   . ASP B 1 291 ? 37.534  -34.138 37.626  1.00 25.78  ? 291 ASP B O   1 
ATOM   4446  C  CB  . ASP B 1 291 ? 40.098  -34.691 36.254  1.00 27.37  ? 291 ASP B CB  1 
ATOM   4447  C  CG  . ASP B 1 291 ? 41.112  -35.680 35.677  1.00 29.93  ? 291 ASP B CG  1 
ATOM   4448  O  OD1 . ASP B 1 291 ? 40.737  -36.841 35.381  1.00 30.85  ? 291 ASP B OD1 1 
ATOM   4449  O  OD2 . ASP B 1 291 ? 42.264  -35.264 35.517  1.00 28.68  ? 291 ASP B OD2 1 
ATOM   4450  N  N   . PHE B 1 292 ? 37.037  -32.973 35.808  1.00 34.47  ? 292 PHE B N   1 
ATOM   4451  C  CA  . PHE B 1 292 ? 36.041  -32.155 36.487  1.00 30.58  ? 292 PHE B CA  1 
ATOM   4452  C  C   . PHE B 1 292 ? 34.738  -32.088 35.707  1.00 28.63  ? 292 PHE B C   1 
ATOM   4453  O  O   . PHE B 1 292 ? 33.848  -31.351 36.089  1.00 30.86  ? 292 PHE B O   1 
ATOM   4454  C  CB  . PHE B 1 292 ? 36.586  -30.736 36.620  1.00 28.48  ? 292 PHE B CB  1 
ATOM   4455  C  CG  . PHE B 1 292 ? 37.884  -30.738 37.391  1.00 28.03  ? 292 PHE B CG  1 
ATOM   4456  C  CD1 . PHE B 1 292 ? 37.892  -30.733 38.777  1.00 24.32  ? 292 PHE B CD1 1 
ATOM   4457  C  CD2 . PHE B 1 292 ? 39.092  -30.795 36.704  1.00 31.11  ? 292 PHE B CD2 1 
ATOM   4458  C  CE1 . PHE B 1 292 ? 39.085  -30.715 39.445  1.00 25.17  ? 292 PHE B CE1 1 
ATOM   4459  C  CE2 . PHE B 1 292 ? 40.296  -30.801 37.392  1.00 31.98  ? 292 PHE B CE2 1 
ATOM   4460  C  CZ  . PHE B 1 292 ? 40.287  -30.744 38.756  1.00 28.17  ? 292 PHE B CZ  1 
ATOM   4461  N  N   . SER B 1 293 ? 34.648  -32.840 34.616  1.00 27.51  ? 293 SER B N   1 
ATOM   4462  C  CA  . SER B 1 293 ? 33.533  -32.697 33.704  1.00 31.39  ? 293 SER B CA  1 
ATOM   4463  C  C   . SER B 1 293 ? 33.155  -34.089 33.214  1.00 34.28  ? 293 SER B C   1 
ATOM   4464  O  O   . SER B 1 293 ? 34.042  -34.775 32.719  1.00 35.84  ? 293 SER B O   1 
ATOM   4465  C  CB  . SER B 1 293 ? 33.885  -31.790 32.527  1.00 30.72  ? 293 SER B CB  1 
ATOM   4466  O  OG  . SER B 1 293 ? 34.644  -30.660 32.953  1.00 31.68  ? 293 SER B OG  1 
ATOM   4467  N  N   . THR B 1 294 ? 31.877  -34.482 33.377  1.00 27.34  ? 294 THR B N   1 
ATOM   4468  C  CA  . THR B 1 294 ? 31.395  -35.757 32.893  1.00 28.87  ? 294 THR B CA  1 
ATOM   4469  C  C   . THR B 1 294 ? 30.369  -35.522 31.791  1.00 28.27  ? 294 THR B C   1 
ATOM   4470  O  O   . THR B 1 294 ? 29.395  -34.806 32.010  1.00 27.14  ? 294 THR B O   1 
ATOM   4471  C  CB  . THR B 1 294 ? 30.766  -36.512 34.073  1.00 29.16  ? 294 THR B CB  1 
ATOM   4472  O  OG1 . THR B 1 294 ? 31.744  -36.648 35.105  1.00 22.75  ? 294 THR B OG1 1 
ATOM   4473  C  CG2 . THR B 1 294 ? 30.202  -37.852 33.632  1.00 28.58  ? 294 THR B CG2 1 
ATOM   4474  N  N   . ALA B 1 295 ? 30.572  -36.187 30.643  1.00 29.54  ? 295 ALA B N   1 
ATOM   4475  C  CA  . ALA B 1 295 ? 29.637  -36.163 29.528  1.00 28.08  ? 295 ALA B CA  1 
ATOM   4476  C  C   . ALA B 1 295 ? 28.506  -37.125 29.809  1.00 30.04  ? 295 ALA B C   1 
ATOM   4477  O  O   . ALA B 1 295 ? 28.765  -38.283 30.045  1.00 37.91  ? 295 ALA B O   1 
ATOM   4478  C  CB  . ALA B 1 295 ? 30.322  -36.553 28.239  1.00 30.14  ? 295 ALA B CB  1 
ATOM   4479  N  N   . VAL B 1 296 ? 27.263  -36.661 29.739  1.00 30.74  ? 296 VAL B N   1 
ATOM   4480  C  CA  . VAL B 1 296 ? 26.104  -37.524 29.936  1.00 33.46  ? 296 VAL B CA  1 
ATOM   4481  C  C   . VAL B 1 296 ? 25.234  -37.610 28.681  1.00 32.45  ? 296 VAL B C   1 
ATOM   4482  O  O   . VAL B 1 296 ? 24.280  -38.353 28.680  1.00 34.82  ? 296 VAL B O   1 
ATOM   4483  C  CB  . VAL B 1 296 ? 25.275  -37.061 31.152  1.00 31.54  ? 296 VAL B CB  1 
ATOM   4484  C  CG1 . VAL B 1 296 ? 26.152  -37.064 32.387  1.00 30.36  ? 296 VAL B CG1 1 
ATOM   4485  C  CG2 . VAL B 1 296 ? 24.593  -35.708 30.937  1.00 29.65  ? 296 VAL B CG2 1 
ATOM   4486  N  N   . THR B 1 297 ? 25.548  -36.854 27.621  1.00 36.98  ? 297 THR B N   1 
ATOM   4487  C  CA  . THR B 1 297 ? 24.949  -37.076 26.311  1.00 31.86  ? 297 THR B CA  1 
ATOM   4488  C  C   . THR B 1 297 ? 26.035  -36.991 25.250  1.00 30.73  ? 297 THR B C   1 
ATOM   4489  O  O   . THR B 1 297 ? 27.180  -36.586 25.491  1.00 32.89  ? 297 THR B O   1 
ATOM   4490  C  CB  . THR B 1 297 ? 23.801  -36.129 25.972  1.00 27.75  ? 297 THR B CB  1 
ATOM   4491  O  OG1 . THR B 1 297 ? 24.322  -34.820 25.762  1.00 27.18  ? 297 THR B OG1 1 
ATOM   4492  C  CG2 . THR B 1 297 ? 22.748  -36.120 27.057  1.00 26.79  ? 297 THR B CG2 1 
ATOM   4493  N  N   . GLY B 1 298 ? 25.651  -37.471 24.076  1.00 30.22  ? 298 GLY B N   1 
ATOM   4494  C  CA  . GLY B 1 298 ? 26.546  -37.432 22.937  1.00 32.50  ? 298 GLY B CA  1 
ATOM   4495  C  C   . GLY B 1 298 ? 25.774  -37.748 21.663  1.00 31.92  ? 298 GLY B C   1 
ATOM   4496  O  O   . GLY B 1 298 ? 25.173  -38.803 21.564  1.00 34.16  ? 298 GLY B O   1 
ATOM   4497  N  N   . SER B 1 299 ? 25.765  -36.805 20.711  1.00 33.17  ? 299 SER B N   1 
ATOM   4498  C  CA  . SER B 1 299 ? 25.031  -36.982 19.469  1.00 30.17  ? 299 SER B CA  1 
ATOM   4499  C  C   . SER B 1 299 ? 25.684  -36.184 18.375  1.00 28.30  ? 299 SER B C   1 
ATOM   4500  O  O   . SER B 1 299 ? 26.336  -35.173 18.660  1.00 27.76  ? 299 SER B O   1 
ATOM   4501  C  CB  . SER B 1 299 ? 23.594  -36.589 19.593  1.00 29.78  ? 299 SER B CB  1 
ATOM   4502  O  OG  . SER B 1 299 ? 22.963  -37.420 20.561  1.00 28.08  ? 299 SER B OG  1 
ATOM   4503  N  N   . LEU B 1 300 ? 25.452  -36.665 17.143  1.00 32.33  ? 300 LEU B N   1 
ATOM   4504  C  CA  . LEU B 1 300 ? 25.971  -36.015 15.950  1.00 36.30  ? 300 LEU B CA  1 
ATOM   4505  C  C   . LEU B 1 300 ? 24.830  -35.730 14.983  1.00 29.24  ? 300 LEU B C   1 
ATOM   4506  O  O   . LEU B 1 300 ? 23.973  -36.579 14.782  1.00 28.01  ? 300 LEU B O   1 
ATOM   4507  C  CB  . LEU B 1 300 ? 27.038  -36.927 15.352  1.00 39.33  ? 300 LEU B CB  1 
ATOM   4508  C  CG  . LEU B 1 300 ? 27.922  -36.327 14.253  1.00 43.33  ? 300 LEU B CG  1 
ATOM   4509  C  CD1 . LEU B 1 300 ? 29.179  -37.142 13.988  1.00 48.22  ? 300 LEU B CD1 1 
ATOM   4510  C  CD2 . LEU B 1 300 ? 27.180  -36.255 12.964  1.00 48.73  ? 300 LEU B CD2 1 
ATOM   4511  N  N   . PHE B 1 301 ? 24.858  -34.542 14.384  1.00 27.29  ? 301 PHE B N   1 
ATOM   4512  C  CA  . PHE B 1 301 ? 23.826  -34.133 13.448  1.00 28.77  ? 301 PHE B CA  1 
ATOM   4513  C  C   . PHE B 1 301 ? 24.436  -33.446 12.236  1.00 27.88  ? 301 PHE B C   1 
ATOM   4514  O  O   . PHE B 1 301 ? 25.520  -32.879 12.302  1.00 27.32  ? 301 PHE B O   1 
ATOM   4515  C  CB  . PHE B 1 301 ? 22.853  -33.131 14.075  1.00 30.67  ? 301 PHE B CB  1 
ATOM   4516  C  CG  . PHE B 1 301 ? 22.234  -33.641 15.353  1.00 27.57  ? 301 PHE B CG  1 
ATOM   4517  C  CD1 . PHE B 1 301 ? 21.070  -34.374 15.327  1.00 27.66  ? 301 PHE B CD1 1 
ATOM   4518  C  CD2 . PHE B 1 301 ? 22.832  -33.386 16.567  1.00 30.00  ? 301 PHE B CD2 1 
ATOM   4519  C  CE1 . PHE B 1 301 ? 20.514  -34.855 16.497  1.00 31.18  ? 301 PHE B CE1 1 
ATOM   4520  C  CE2 . PHE B 1 301 ? 22.284  -33.871 17.723  1.00 30.13  ? 301 PHE B CE2 1 
ATOM   4521  C  CZ  . PHE B 1 301 ? 21.127  -34.608 17.689  1.00 32.18  ? 301 PHE B CZ  1 
ATOM   4522  N  N   . PHE B 1 302 ? 23.689  -33.508 11.134  1.00 30.92  ? 302 PHE B N   1 
ATOM   4523  C  CA  . PHE B 1 302 ? 23.992  -32.736 9.947   1.00 31.13  ? 302 PHE B CA  1 
ATOM   4524  C  C   . PHE B 1 302 ? 22.976  -31.602 9.884   1.00 30.25  ? 302 PHE B C   1 
ATOM   4525  O  O   . PHE B 1 302 ? 21.768  -31.846 9.987   1.00 32.42  ? 302 PHE B O   1 
ATOM   4526  C  CB  . PHE B 1 302 ? 23.943  -33.661 8.722   1.00 31.43  ? 302 PHE B CB  1 
ATOM   4527  C  CG  . PHE B 1 302 ? 24.220  -32.882 7.456   1.00 29.74  ? 302 PHE B CG  1 
ATOM   4528  C  CD1 . PHE B 1 302 ? 25.506  -32.472 7.156   1.00 35.85  ? 302 PHE B CD1 1 
ATOM   4529  C  CD2 . PHE B 1 302 ? 23.198  -32.518 6.600   1.00 32.12  ? 302 PHE B CD2 1 
ATOM   4530  C  CE1 . PHE B 1 302 ? 25.779  -31.734 6.012   1.00 36.06  ? 302 PHE B CE1 1 
ATOM   4531  C  CE2 . PHE B 1 302 ? 23.472  -31.814 5.443   1.00 35.09  ? 302 PHE B CE2 1 
ATOM   4532  C  CZ  . PHE B 1 302 ? 24.758  -31.385 5.172   1.00 35.94  ? 302 PHE B CZ  1 
ATOM   4533  N  N   . THR B 1 303 ? 23.490  -30.379 9.728   1.00 28.34  ? 303 THR B N   1 
ATOM   4534  C  CA  . THR B 1 303 ? 22.635  -29.206 9.606   1.00 30.28  ? 303 THR B CA  1 
ATOM   4535  C  C   . THR B 1 303 ? 22.665  -28.786 8.136   1.00 32.56  ? 303 THR B C   1 
ATOM   4536  O  O   . THR B 1 303 ? 23.639  -28.178 7.685   1.00 31.93  ? 303 THR B O   1 
ATOM   4537  C  CB  . THR B 1 303 ? 23.075  -28.074 10.538  1.00 28.13  ? 303 THR B CB  1 
ATOM   4538  O  OG1 . THR B 1 303 ? 24.384  -27.620 10.227  1.00 25.11  ? 303 THR B OG1 1 
ATOM   4539  C  CG2 . THR B 1 303 ? 23.130  -28.508 11.991  1.00 28.60  ? 303 THR B CG2 1 
ATOM   4540  N  N   . PRO B 1 304 ? 21.604  -29.088 7.357   1.00 32.13  ? 304 PRO B N   1 
ATOM   4541  C  CA  . PRO B 1 304 ? 21.604  -28.807 5.921   1.00 33.60  ? 304 PRO B CA  1 
ATOM   4542  C  C   . PRO B 1 304 ? 21.607  -27.327 5.619   1.00 36.67  ? 304 PRO B C   1 
ATOM   4543  O  O   . PRO B 1 304 ? 21.318  -26.499 6.493   1.00 35.86  ? 304 PRO B O   1 
ATOM   4544  C  CB  . PRO B 1 304 ? 20.309  -29.429 5.407   1.00 36.11  ? 304 PRO B CB  1 
ATOM   4545  C  CG  . PRO B 1 304 ? 19.771  -30.274 6.557   1.00 35.52  ? 304 PRO B CG  1 
ATOM   4546  C  CD  . PRO B 1 304 ? 20.361  -29.721 7.825   1.00 32.57  ? 304 PRO B CD  1 
ATOM   4547  N  N   . ALA B 1 305 ? 21.919  -27.012 4.358   1.00 39.27  ? 305 ALA B N   1 
ATOM   4548  C  CA  . ALA B 1 305 ? 21.681  -25.661 3.873   1.00 42.36  ? 305 ALA B CA  1 
ATOM   4549  C  C   . ALA B 1 305 ? 20.190  -25.350 4.028   1.00 40.37  ? 305 ALA B C   1 
ATOM   4550  O  O   . ALA B 1 305 ? 19.348  -26.266 3.990   1.00 32.18  ? 305 ALA B O   1 
ATOM   4551  C  CB  . ALA B 1 305 ? 22.157  -25.500 2.443   1.00 42.61  ? 305 ALA B CB  1 
ATOM   4552  N  N   . ALA B 1 306 ? 19.893  -24.056 4.235   1.00 40.09  ? 306 ALA B N   1 
ATOM   4553  C  CA  . ALA B 1 306 ? 18.525  -23.606 4.458   1.00 38.51  ? 306 ALA B CA  1 
ATOM   4554  C  C   . ALA B 1 306 ? 17.605  -23.998 3.293   1.00 41.68  ? 306 ALA B C   1 
ATOM   4555  O  O   . ALA B 1 306 ? 16.489  -24.447 3.541   1.00 34.71  ? 306 ALA B O   1 
ATOM   4556  C  CB  . ALA B 1 306 ? 18.532  -22.122 4.692   1.00 38.68  ? 306 ALA B CB  1 
ATOM   4557  N  N   . ASP B 1 307 ? 18.095  -23.849 2.039   1.00 46.05  ? 307 ASP B N   1 
ATOM   4558  C  CA  . ASP B 1 307 ? 17.339  -24.150 0.825   1.00 43.68  ? 307 ASP B CA  1 
ATOM   4559  C  C   . ASP B 1 307 ? 16.834  -25.587 0.849   1.00 44.11  ? 307 ASP B C   1 
ATOM   4560  O  O   . ASP B 1 307 ? 15.726  -25.877 0.397   1.00 44.17  ? 307 ASP B O   1 
ATOM   4561  C  CB  . ASP B 1 307 ? 18.186  -24.135 -0.431  1.00 48.29  ? 307 ASP B CB  1 
ATOM   4562  C  CG  . ASP B 1 307 ? 19.338  -23.160 -0.413  1.00 65.19  ? 307 ASP B CG  1 
ATOM   4563  O  OD1 . ASP B 1 307 ? 19.046  -21.954 -0.447  1.00 97.75  ? 307 ASP B OD1 1 
ATOM   4564  O  OD2 . ASP B 1 307 ? 20.487  -23.635 -0.334  1.00 80.89  ? 307 ASP B OD2 1 
ATOM   4565  N  N   . PHE B 1 308 ? 17.692  -26.498 1.331   1.00 44.30  ? 308 PHE B N   1 
ATOM   4566  C  CA  . PHE B 1 308 ? 17.373  -27.920 1.371   1.00 42.37  ? 308 PHE B CA  1 
ATOM   4567  C  C   . PHE B 1 308 ? 16.065  -28.130 2.140   1.00 39.21  ? 308 PHE B C   1 
ATOM   4568  O  O   . PHE B 1 308 ? 15.227  -28.899 1.694   1.00 43.60  ? 308 PHE B O   1 
ATOM   4569  C  CB  . PHE B 1 308 ? 18.554  -28.722 1.937   1.00 36.44  ? 308 PHE B CB  1 
ATOM   4570  C  CG  . PHE B 1 308 ? 18.282  -30.215 2.037   1.00 39.44  ? 308 PHE B CG  1 
ATOM   4571  C  CD1 . PHE B 1 308 ? 17.567  -30.764 3.099   1.00 43.00  ? 308 PHE B CD1 1 
ATOM   4572  C  CD2 . PHE B 1 308 ? 18.782  -31.075 1.081   1.00 42.11  ? 308 PHE B CD2 1 
ATOM   4573  C  CE1 . PHE B 1 308 ? 17.310  -32.135 3.163   1.00 47.43  ? 308 PHE B CE1 1 
ATOM   4574  C  CE2 . PHE B 1 308 ? 18.523  -32.448 1.147   1.00 44.40  ? 308 PHE B CE2 1 
ATOM   4575  C  CZ  . PHE B 1 308 ? 17.780  -32.973 2.176   1.00 44.07  ? 308 PHE B CZ  1 
ATOM   4576  N  N   . LEU B 1 309 ? 15.885  -27.438 3.276   1.00 41.75  ? 309 LEU B N   1 
ATOM   4577  C  CA  . LEU B 1 309 ? 14.683  -27.579 4.098   1.00 41.90  ? 309 LEU B CA  1 
ATOM   4578  C  C   . LEU B 1 309 ? 13.462  -26.912 3.443   1.00 43.13  ? 309 LEU B C   1 
ATOM   4579  O  O   . LEU B 1 309 ? 12.361  -27.457 3.560   1.00 42.33  ? 309 LEU B O   1 
ATOM   4580  C  CB  . LEU B 1 309 ? 14.921  -27.001 5.494   1.00 41.49  ? 309 LEU B CB  1 
ATOM   4581  C  CG  . LEU B 1 309 ? 16.035  -27.597 6.352   1.00 40.33  ? 309 LEU B CG  1 
ATOM   4582  C  CD1 . LEU B 1 309 ? 16.333  -26.676 7.502   1.00 37.85  ? 309 LEU B CD1 1 
ATOM   4583  C  CD2 . LEU B 1 309 ? 15.632  -28.943 6.863   1.00 41.11  ? 309 LEU B CD2 1 
ATOM   4584  N  N   . GLU B 1 310 ? 13.646  -25.734 2.787   1.00 48.89  ? 310 GLU B N   1 
ATOM   4585  C  CA  . GLU B 1 310 ? 12.574  -24.967 2.143   1.00 46.21  ? 310 GLU B CA  1 
ATOM   4586  C  C   . GLU B 1 310 ? 11.812  -25.934 1.228   1.00 57.49  ? 310 GLU B C   1 
ATOM   4587  O  O   . GLU B 1 310 ? 10.592  -25.960 1.271   1.00 68.65  ? 310 GLU B O   1 
ATOM   4588  C  CB  . GLU B 1 310 ? 13.120  -23.699 1.443   1.00 47.95  ? 310 GLU B CB  1 
ATOM   4589  C  CG  . GLU B 1 310 ? 12.216  -22.470 1.276   1.00 41.48  ? 310 GLU B CG  1 
ATOM   4590  N  N   . ASP B 1 311 ? 12.544  -26.798 0.485   1.00 66.60  ? 311 ASP B N   1 
ATOM   4591  C  CA  . ASP B 1 311 ? 12.022  -27.945 -0.269  1.00 58.48  ? 311 ASP B CA  1 
ATOM   4592  C  C   . ASP B 1 311 ? 12.047  -29.251 0.540   1.00 46.03  ? 311 ASP B C   1 
ATOM   4593  O  O   . ASP B 1 311 ? 10.963  -29.807 0.744   1.00 48.02  ? 311 ASP B O   1 
ATOM   4594  C  CB  . ASP B 1 311 ? 12.903  -28.198 -1.476  1.00 58.31  ? 311 ASP B CB  1 
ATOM   4595  C  CG  . ASP B 1 311 ? 13.445  -26.954 -2.191  1.00 62.23  ? 311 ASP B CG  1 
ATOM   4596  O  OD1 . ASP B 1 311 ? 13.058  -25.819 -1.819  1.00 64.17  ? 311 ASP B OD1 1 
ATOM   4597  O  OD2 . ASP B 1 311 ? 14.267  -27.111 -3.107  1.00 62.75  ? 311 ASP B OD2 1 
ATOM   4598  N  N   . GLU C 1 7   ? 32.795  -3.693  -10.971 1.00 103.16 ? 7   GLU C N   1 
ATOM   4599  C  CA  . GLU C 1 7   ? 32.370  -2.277  -10.784 1.00 99.02  ? 7   GLU C CA  1 
ATOM   4600  C  C   . GLU C 1 7   ? 31.142  -2.258  -9.838  1.00 95.53  ? 7   GLU C C   1 
ATOM   4601  O  O   . GLU C 1 7   ? 31.269  -2.722  -8.712  1.00 82.68  ? 7   GLU C O   1 
ATOM   4602  C  CB  . GLU C 1 7   ? 32.431  -1.562  -12.148 1.00 76.02  ? 7   GLU C CB  1 
ATOM   4603  N  N   . PRO C 1 8   ? 29.882  -1.926  -10.237 1.00 91.56  ? 8   PRO C N   1 
ATOM   4604  C  CA  . PRO C 1 8   ? 29.178  -0.756  -9.689  1.00 78.81  ? 8   PRO C CA  1 
ATOM   4605  C  C   . PRO C 1 8   ? 28.491  -0.820  -8.319  1.00 59.96  ? 8   PRO C C   1 
ATOM   4606  O  O   . PRO C 1 8   ? 27.846  -1.816  -7.995  1.00 48.09  ? 8   PRO C O   1 
ATOM   4607  C  CB  . PRO C 1 8   ? 28.159  -0.502  -10.823 1.00 79.25  ? 8   PRO C CB  1 
ATOM   4608  C  CG  . PRO C 1 8   ? 27.753  -1.897  -11.243 1.00 84.11  ? 8   PRO C CG  1 
ATOM   4609  C  CD  . PRO C 1 8   ? 28.954  -2.807  -10.969 1.00 84.50  ? 8   PRO C CD  1 
ATOM   4610  N  N   . GLU C 1 9   ? 28.625  0.302   -7.563  1.00 52.76  ? 9   GLU C N   1 
ATOM   4611  C  CA  . GLU C 1 9   ? 28.138  0.485   -6.194  1.00 52.24  ? 9   GLU C CA  1 
ATOM   4612  C  C   . GLU C 1 9   ? 26.665  0.937   -6.282  1.00 49.33  ? 9   GLU C C   1 
ATOM   4613  O  O   . GLU C 1 9   ? 26.355  1.995   -6.830  1.00 39.48  ? 9   GLU C O   1 
ATOM   4614  C  CB  . GLU C 1 9   ? 29.061  1.383   -5.324  1.00 51.50  ? 9   GLU C CB  1 
ATOM   4615  C  CG  . GLU C 1 9   ? 29.925  0.658   -4.273  1.00 44.43  ? 9   GLU C CG  1 
ATOM   4616  N  N   . PRO C 1 10  ? 25.675  0.156   -5.768  1.00 43.07  ? 10  PRO C N   1 
ATOM   4617  C  CA  . PRO C 1 10  ? 24.276  0.597   -5.711  1.00 46.36  ? 10  PRO C CA  1 
ATOM   4618  C  C   . PRO C 1 10  ? 24.057  1.690   -4.677  1.00 41.86  ? 10  PRO C C   1 
ATOM   4619  O  O   . PRO C 1 10  ? 24.905  1.888   -3.813  1.00 29.72  ? 10  PRO C O   1 
ATOM   4620  C  CB  . PRO C 1 10  ? 23.508  -0.676  -5.314  1.00 45.11  ? 10  PRO C CB  1 
ATOM   4621  C  CG  . PRO C 1 10  ? 24.511  -1.411  -4.472  1.00 43.39  ? 10  PRO C CG  1 
ATOM   4622  C  CD  . PRO C 1 10  ? 25.817  -1.206  -5.241  1.00 43.12  ? 10  PRO C CD  1 
ATOM   4623  N  N   . GLN C 1 11  ? 22.883  2.351   -4.759  1.00 48.35  ? 11  GLN C N   1 
ATOM   4624  C  CA  . GLN C 1 11  ? 22.434  3.213   -3.660  1.00 44.01  ? 11  GLN C CA  1 
ATOM   4625  C  C   . GLN C 1 11  ? 22.155  2.350   -2.419  1.00 35.89  ? 11  GLN C C   1 
ATOM   4626  O  O   . GLN C 1 11  ? 22.237  1.127   -2.491  1.00 30.60  ? 11  GLN C O   1 
ATOM   4627  C  CB  . GLN C 1 11  ? 21.264  4.101   -4.090  1.00 34.96  ? 11  GLN C CB  1 
ATOM   4628  C  CG  . GLN C 1 11  ? 21.698  5.160   -5.091  1.00 31.24  ? 11  GLN C CG  1 
ATOM   4629  C  CD  . GLN C 1 11  ? 20.593  6.128   -5.416  1.00 27.92  ? 11  GLN C CD  1 
ATOM   4630  O  OE1 . GLN C 1 11  ? 20.226  6.976   -4.606  1.00 29.57  ? 11  GLN C OE1 1 
ATOM   4631  N  NE2 . GLN C 1 11  ? 20.027  5.993   -6.595  1.00 26.10  ? 11  GLN C NE2 1 
ATOM   4632  N  N   . MET C 1 12  ? 21.816  2.974   -1.288  1.00 34.25  ? 12  MET C N   1 
ATOM   4633  C  CA  . MET C 1 12  ? 21.474  2.228   -0.085  1.00 38.39  ? 12  MET C CA  1 
ATOM   4634  C  C   . MET C 1 12  ? 20.028  1.732   -0.125  1.00 34.30  ? 12  MET C C   1 
ATOM   4635  O  O   . MET C 1 12  ? 19.227  1.919   0.798   1.00 29.90  ? 12  MET C O   1 
ATOM   4636  C  CB  . MET C 1 12  ? 21.648  3.081   1.171   1.00 49.50  ? 12  MET C CB  1 
ATOM   4637  C  CG  . MET C 1 12  ? 21.792  2.274   2.458   1.00 57.84  ? 12  MET C CG  1 
ATOM   4638  S  SD  . MET C 1 12  ? 23.420  1.515   2.569   1.00 67.43  ? 12  MET C SD  1 
ATOM   4639  C  CE  . MET C 1 12  ? 24.545  2.251   1.360   1.00 52.72  ? 12  MET C CE  1 
ATOM   4640  N  N   . VAL C 1 13  ? 19.724  0.997   -1.181  1.00 31.77  ? 13  VAL C N   1 
ATOM   4641  C  CA  . VAL C 1 13  ? 18.438  0.354   -1.274  1.00 35.33  ? 13  VAL C CA  1 
ATOM   4642  C  C   . VAL C 1 13  ? 18.280  -0.655  -0.128  1.00 39.44  ? 13  VAL C C   1 
ATOM   4643  O  O   . VAL C 1 13  ? 17.213  -0.656  0.501   1.00 36.63  ? 13  VAL C O   1 
ATOM   4644  C  CB  . VAL C 1 13  ? 18.243  -0.288  -2.652  1.00 32.47  ? 13  VAL C CB  1 
ATOM   4645  C  CG1 . VAL C 1 13  ? 16.886  -0.946  -2.709  1.00 35.84  ? 13  VAL C CG1 1 
ATOM   4646  C  CG2 . VAL C 1 13  ? 18.365  0.752   -3.751  1.00 37.88  ? 13  VAL C CG2 1 
ATOM   4647  N  N   . LEU C 1 14  ? 19.306  -1.505  0.118   1.00 38.23  ? 14  LEU C N   1 
ATOM   4648  C  CA  . LEU C 1 14  ? 19.242  -2.496  1.183   1.00 38.13  ? 14  LEU C CA  1 
ATOM   4649  C  C   . LEU C 1 14  ? 19.720  -1.796  2.441   1.00 39.94  ? 14  LEU C C   1 
ATOM   4650  O  O   . LEU C 1 14  ? 20.902  -1.732  2.711   1.00 47.98  ? 14  LEU C O   1 
ATOM   4651  C  CB  . LEU C 1 14  ? 20.075  -3.732  0.860   1.00 39.29  ? 14  LEU C CB  1 
ATOM   4652  C  CG  . LEU C 1 14  ? 19.930  -4.301  -0.561  1.00 48.57  ? 14  LEU C CG  1 
ATOM   4653  C  CD1 . LEU C 1 14  ? 21.128  -5.168  -0.991  1.00 59.67  ? 14  LEU C CD1 1 
ATOM   4654  C  CD2 . LEU C 1 14  ? 18.694  -5.150  -0.750  1.00 47.95  ? 14  LEU C CD2 1 
ATOM   4655  N  N   . SER C 1 15  ? 18.805  -1.140  3.137   1.00 42.94  ? 15  SER C N   1 
ATOM   4656  C  CA  . SER C 1 15  ? 19.168  -0.426  4.339   1.00 46.43  ? 15  SER C CA  1 
ATOM   4657  C  C   . SER C 1 15  ? 18.834  -1.330  5.523   1.00 49.95  ? 15  SER C C   1 
ATOM   4658  O  O   . SER C 1 15  ? 17.899  -2.127  5.499   1.00 49.87  ? 15  SER C O   1 
ATOM   4659  C  CB  . SER C 1 15  ? 18.518  0.957   4.409   1.00 42.61  ? 15  SER C CB  1 
ATOM   4660  O  OG  . SER C 1 15  ? 18.537  1.570   5.692   1.00 44.50  ? 15  SER C OG  1 
ATOM   4661  N  N   . PRO C 1 16  ? 19.618  -1.256  6.618   1.00 63.80  ? 16  PRO C N   1 
ATOM   4662  C  CA  . PRO C 1 16  ? 19.153  -1.794  7.896   1.00 61.32  ? 16  PRO C CA  1 
ATOM   4663  C  C   . PRO C 1 16  ? 17.767  -1.255  8.214   1.00 52.65  ? 16  PRO C C   1 
ATOM   4664  O  O   . PRO C 1 16  ? 17.336  -0.237  7.670   1.00 47.70  ? 16  PRO C O   1 
ATOM   4665  C  CB  . PRO C 1 16  ? 20.187  -1.256  8.907   1.00 68.94  ? 16  PRO C CB  1 
ATOM   4666  C  CG  . PRO C 1 16  ? 20.994  -0.179  8.146   1.00 65.47  ? 16  PRO C CG  1 
ATOM   4667  C  CD  . PRO C 1 16  ? 20.949  -0.615  6.693   1.00 60.73  ? 16  PRO C CD  1 
ATOM   4668  N  N   . LEU C 1 17  ? 17.125  -1.907  9.172   1.00 54.61  ? 17  LEU C N   1 
ATOM   4669  C  CA  . LEU C 1 17  ? 15.941  -1.349  9.813   1.00 56.28  ? 17  LEU C CA  1 
ATOM   4670  C  C   . LEU C 1 17  ? 16.287  0.037   10.369  1.00 47.43  ? 17  LEU C C   1 
ATOM   4671  O  O   . LEU C 1 17  ? 17.311  0.226   11.040  1.00 45.23  ? 17  LEU C O   1 
ATOM   4672  C  CB  . LEU C 1 17  ? 15.313  -2.251  10.890  1.00 52.86  ? 17  LEU C CB  1 
ATOM   4673  C  CG  . LEU C 1 17  ? 14.910  -3.680  10.476  1.00 54.93  ? 17  LEU C CG  1 
ATOM   4674  C  CD1 . LEU C 1 17  ? 13.977  -4.218  11.580  1.00 60.94  ? 17  LEU C CD1 1 
ATOM   4675  C  CD2 . LEU C 1 17  ? 14.320  -3.848  9.036   1.00 45.73  ? 17  LEU C CD2 1 
ATOM   4676  N  N   . THR C 1 18  ? 15.445  0.998   9.959   1.00 37.75  ? 18  THR C N   1 
ATOM   4677  C  CA  . THR C 1 18  ? 15.486  2.383   10.386  1.00 34.49  ? 18  THR C CA  1 
ATOM   4678  C  C   . THR C 1 18  ? 14.073  2.711   10.877  1.00 34.51  ? 18  THR C C   1 
ATOM   4679  O  O   . THR C 1 18  ? 13.076  2.109   10.505  1.00 35.02  ? 18  THR C O   1 
ATOM   4680  C  CB  . THR C 1 18  ? 15.942  3.304   9.252   1.00 33.15  ? 18  THR C CB  1 
ATOM   4681  O  OG1 . THR C 1 18  ? 15.033  3.105   8.174   1.00 38.10  ? 18  THR C OG1 1 
ATOM   4682  C  CG2 . THR C 1 18  ? 17.348  3.027   8.751   1.00 32.59  ? 18  THR C CG2 1 
ATOM   4683  N  N   . SER C 1 19  ? 13.982  3.660   11.779  1.00 32.10  ? 19  SER C N   1 
ATOM   4684  C  CA  . SER C 1 19  ? 12.744  3.885   12.471  1.00 30.70  ? 19  SER C CA  1 
ATOM   4685  C  C   . SER C 1 19  ? 12.173  5.257   12.129  1.00 26.70  ? 19  SER C C   1 
ATOM   4686  O  O   . SER C 1 19  ? 11.120  5.603   12.631  1.00 30.80  ? 19  SER C O   1 
ATOM   4687  C  CB  . SER C 1 19  ? 12.992  3.716   13.930  1.00 34.26  ? 19  SER C CB  1 
ATOM   4688  O  OG  . SER C 1 19  ? 14.250  4.309   14.172  1.00 36.69  ? 19  SER C OG  1 
ATOM   4689  N  N   . ALA C 1 20  ? 12.834  6.032   11.279  1.00 22.82  ? 20  ALA C N   1 
ATOM   4690  C  CA  . ALA C 1 20  ? 12.224  7.240   10.756  1.00 23.34  ? 20  ALA C CA  1 
ATOM   4691  C  C   . ALA C 1 20  ? 12.483  7.337   9.271   1.00 22.80  ? 20  ALA C C   1 
ATOM   4692  O  O   . ALA C 1 20  ? 13.550  6.912   8.818   1.00 24.14  ? 20  ALA C O   1 
ATOM   4693  C  CB  . ALA C 1 20  ? 12.800  8.454   11.387  1.00 24.40  ? 20  ALA C CB  1 
ATOM   4694  N  N   . ALA C 1 21  ? 11.534  7.949   8.550   1.00 22.80  ? 21  ALA C N   1 
ATOM   4695  C  CA  . ALA C 1 21  ? 11.782  8.244   7.157   1.00 20.52  ? 21  ALA C CA  1 
ATOM   4696  C  C   . ALA C 1 21  ? 11.108  9.543   6.752   1.00 20.56  ? 21  ALA C C   1 
ATOM   4697  O  O   . ALA C 1 21  ? 10.081  9.920   7.325   1.00 21.10  ? 21  ALA C O   1 
ATOM   4698  C  CB  . ALA C 1 21  ? 11.301  7.110   6.331   1.00 21.31  ? 21  ALA C CB  1 
ATOM   4699  N  N   . ILE C 1 22  ? 11.702  10.191  5.747   1.00 18.49  ? 22  ILE C N   1 
ATOM   4700  C  CA  . ILE C 1 22  ? 11.001  11.186  4.955   1.00 19.87  ? 22  ILE C CA  1 
ATOM   4701  C  C   . ILE C 1 22  ? 10.936  10.757  3.494   1.00 20.55  ? 22  ILE C C   1 
ATOM   4702  O  O   . ILE C 1 22  ? 11.943  10.414  2.913   1.00 23.53  ? 22  ILE C O   1 
ATOM   4703  C  CB  . ILE C 1 22  ? 11.647  12.570  5.114   1.00 19.37  ? 22  ILE C CB  1 
ATOM   4704  C  CG1 . ILE C 1 22  ? 11.432  13.070  6.500   1.00 20.16  ? 22  ILE C CG1 1 
ATOM   4705  C  CG2 . ILE C 1 22  ? 11.109  13.540  4.053   1.00 20.09  ? 22  ILE C CG2 1 
ATOM   4706  C  CD1 . ILE C 1 22  ? 12.130  14.380  6.810   1.00 21.69  ? 22  ILE C CD1 1 
ATOM   4707  N  N   . PHE C 1 23  ? 9.742   10.815  2.911   1.00 20.76  ? 23  PHE C N   1 
ATOM   4708  C  CA  . PHE C 1 23  ? 9.532   10.591  1.498   1.00 21.96  ? 23  PHE C CA  1 
ATOM   4709  C  C   . PHE C 1 23  ? 9.225   11.944  0.880   1.00 21.46  ? 23  PHE C C   1 
ATOM   4710  O  O   . PHE C 1 23  ? 8.307   12.635  1.283   1.00 21.93  ? 23  PHE C O   1 
ATOM   4711  C  CB  . PHE C 1 23  ? 8.352   9.654   1.220   1.00 22.24  ? 23  PHE C CB  1 
ATOM   4712  C  CG  . PHE C 1 23  ? 8.458   8.307   1.888   1.00 23.12  ? 23  PHE C CG  1 
ATOM   4713  C  CD1 . PHE C 1 23  ? 9.119   7.265   1.266   1.00 24.51  ? 23  PHE C CD1 1 
ATOM   4714  C  CD2 . PHE C 1 23  ? 7.958   8.107   3.168   1.00 25.90  ? 23  PHE C CD2 1 
ATOM   4715  C  CE1 . PHE C 1 23  ? 9.229   6.021   1.885   1.00 25.67  ? 23  PHE C CE1 1 
ATOM   4716  C  CE2 . PHE C 1 23  ? 8.118   6.869   3.805   1.00 25.22  ? 23  PHE C CE2 1 
ATOM   4717  C  CZ  . PHE C 1 23  ? 8.741   5.828   3.160   1.00 23.07  ? 23  PHE C CZ  1 
ATOM   4718  N  N   . LEU C 1 24  ? 9.978   12.305  -0.134  1.00 22.52  ? 24  LEU C N   1 
ATOM   4719  C  CA  . LEU C 1 24  ? 9.783   13.566  -0.812  1.00 24.47  ? 24  LEU C CA  1 
ATOM   4720  C  C   . LEU C 1 24  ? 9.639   13.307  -2.306  1.00 22.60  ? 24  LEU C C   1 
ATOM   4721  O  O   . LEU C 1 24  ? 10.477  12.668  -2.901  1.00 23.46  ? 24  LEU C O   1 
ATOM   4722  C  CB  . LEU C 1 24  ? 11.024  14.357  -0.447  1.00 28.38  ? 24  LEU C CB  1 
ATOM   4723  C  CG  . LEU C 1 24  ? 10.957  15.863  -0.653  1.00 34.70  ? 24  LEU C CG  1 
ATOM   4724  C  CD1 . LEU C 1 24  ? 9.733   16.563  -0.062  1.00 37.35  ? 24  LEU C CD1 1 
ATOM   4725  C  CD2 . LEU C 1 24  ? 12.227  16.309  0.033   1.00 40.25  ? 24  LEU C CD2 1 
ATOM   4726  N  N   . VAL C 1 25  ? 8.541   13.754  -2.902  1.00 21.80  ? 25  VAL C N   1 
ATOM   4727  C  CA  . VAL C 1 25  ? 8.286   13.551  -4.317  1.00 21.61  ? 25  VAL C CA  1 
ATOM   4728  C  C   . VAL C 1 25  ? 8.073   14.923  -4.903  1.00 19.91  ? 25  VAL C C   1 
ATOM   4729  O  O   . VAL C 1 25  ? 7.266   15.657  -4.373  1.00 18.87  ? 25  VAL C O   1 
ATOM   4730  C  CB  . VAL C 1 25  ? 7.080   12.641  -4.617  1.00 21.18  ? 25  VAL C CB  1 
ATOM   4731  C  CG1 . VAL C 1 25  ? 6.784   12.504  -6.101  1.00 18.91  ? 25  VAL C CG1 1 
ATOM   4732  C  CG2 . VAL C 1 25  ? 7.323   11.261  -4.030  1.00 21.90  ? 25  VAL C CG2 1 
ATOM   4733  N  N   . VAL C 1 26  ? 8.822   15.237  -5.955  1.00 19.56  ? 26  VAL C N   1 
ATOM   4734  C  CA  . VAL C 1 26  ? 8.724   16.539  -6.577  1.00 20.97  ? 26  VAL C CA  1 
ATOM   4735  C  C   . VAL C 1 26  ? 8.599   16.367  -8.071  1.00 20.80  ? 26  VAL C C   1 
ATOM   4736  O  O   . VAL C 1 26  ? 9.020   15.339  -8.614  1.00 19.97  ? 26  VAL C O   1 
ATOM   4737  C  CB  . VAL C 1 26  ? 9.941   17.412  -6.240  1.00 22.73  ? 26  VAL C CB  1 
ATOM   4738  C  CG1 . VAL C 1 26  ? 10.153  17.500  -4.740  1.00 23.76  ? 26  VAL C CG1 1 
ATOM   4739  C  CG2 . VAL C 1 26  ? 11.220  16.922  -6.894  1.00 24.56  ? 26  VAL C CG2 1 
ATOM   4740  N  N   . THR C 1 27  ? 8.134   17.449  -8.711  1.00 23.51  ? 27  THR C N   1 
ATOM   4741  C  CA  . THR C 1 27  ? 8.215   17.589  -10.162 1.00 24.09  ? 27  THR C CA  1 
ATOM   4742  C  C   . THR C 1 27  ? 9.229   18.650  -10.531 1.00 23.63  ? 27  THR C C   1 
ATOM   4743  O  O   . THR C 1 27  ? 9.370   19.620  -9.822  1.00 27.28  ? 27  THR C O   1 
ATOM   4744  C  CB  . THR C 1 27  ? 6.853   17.926  -10.744 1.00 22.99  ? 27  THR C CB  1 
ATOM   4745  O  OG1 . THR C 1 27  ? 6.339   19.148  -10.200 1.00 21.79  ? 27  THR C OG1 1 
ATOM   4746  C  CG2 . THR C 1 27  ? 5.946   16.741  -10.482 1.00 25.93  ? 27  THR C CG2 1 
ATOM   4747  N  N   . ILE C 1 28  ? 9.911   18.433  -11.648 1.00 25.28  ? 28  ILE C N   1 
ATOM   4748  C  CA  . ILE C 1 28  ? 10.845  19.393  -12.197 1.00 27.50  ? 28  ILE C CA  1 
ATOM   4749  C  C   . ILE C 1 28  ? 10.076  20.458  -13.013 1.00 30.29  ? 28  ILE C C   1 
ATOM   4750  O  O   . ILE C 1 28  ? 9.347   20.153  -13.959 1.00 34.76  ? 28  ILE C O   1 
ATOM   4751  C  CB  . ILE C 1 28  ? 11.909  18.641  -13.017 1.00 27.61  ? 28  ILE C CB  1 
ATOM   4752  C  CG1 . ILE C 1 28  ? 12.586  17.525  -12.230 1.00 28.31  ? 28  ILE C CG1 1 
ATOM   4753  C  CG2 . ILE C 1 28  ? 12.971  19.602  -13.546 1.00 29.59  ? 28  ILE C CG2 1 
ATOM   4754  C  CD1 . ILE C 1 28  ? 13.523  16.692  -13.087 1.00 29.63  ? 28  ILE C CD1 1 
ATOM   4755  N  N   . ASP C 1 29  ? 10.235  21.732  -12.642 1.00 27.07  ? 29  ASP C N   1 
ATOM   4756  C  CA  . ASP C 1 29  ? 9.683   22.835  -13.405 1.00 29.23  ? 29  ASP C CA  1 
ATOM   4757  C  C   . ASP C 1 29  ? 10.415  22.931  -14.741 1.00 30.19  ? 29  ASP C C   1 
ATOM   4758  O  O   . ASP C 1 29  ? 11.523  22.432  -14.885 1.00 32.24  ? 29  ASP C O   1 
ATOM   4759  C  CB  . ASP C 1 29  ? 9.849   24.146  -12.652 1.00 30.69  ? 29  ASP C CB  1 
ATOM   4760  C  CG  . ASP C 1 29  ? 9.229   24.162  -11.263 1.00 31.19  ? 29  ASP C CG  1 
ATOM   4761  O  OD1 . ASP C 1 29  ? 8.515   23.191  -10.916 1.00 30.62  ? 29  ASP C OD1 1 
ATOM   4762  O  OD2 . ASP C 1 29  ? 9.512   25.135  -10.547 1.00 33.80  ? 29  ASP C OD2 1 
ATOM   4763  N  N   . SER C 1 30  ? 9.810   23.626  -15.702 1.00 35.71  ? 30  SER C N   1 
ATOM   4764  C  CA  . SER C 1 30  ? 10.469  24.029  -16.943 1.00 38.18  ? 30  SER C CA  1 
ATOM   4765  C  C   . SER C 1 30  ? 11.745  24.796  -16.647 1.00 35.03  ? 30  SER C C   1 
ATOM   4766  O  O   . SER C 1 30  ? 11.726  25.740  -15.871 1.00 40.65  ? 30  SER C O   1 
ATOM   4767  C  CB  . SER C 1 30  ? 9.593   24.934  -17.785 1.00 47.14  ? 30  SER C CB  1 
ATOM   4768  O  OG  . SER C 1 30  ? 8.663   24.189  -18.563 1.00 60.19  ? 30  SER C OG  1 
ATOM   4769  N  N   . GLY C 1 31  ? 12.858  24.391  -17.268 1.00 34.38  ? 31  GLY C N   1 
ATOM   4770  C  CA  . GLY C 1 31  ? 14.096  25.125  -17.097 1.00 32.51  ? 31  GLY C CA  1 
ATOM   4771  C  C   . GLY C 1 31  ? 14.858  24.691  -15.852 1.00 32.54  ? 31  GLY C C   1 
ATOM   4772  O  O   . GLY C 1 31  ? 15.973  25.146  -15.664 1.00 33.73  ? 31  GLY C O   1 
ATOM   4773  N  N   . GLY C 1 32  ? 14.306  23.767  -15.055 1.00 29.96  ? 32  GLY C N   1 
ATOM   4774  C  CA  . GLY C 1 32  ? 14.963  23.312  -13.839 1.00 32.09  ? 32  GLY C CA  1 
ATOM   4775  C  C   . GLY C 1 32  ? 16.034  22.236  -14.033 1.00 30.74  ? 32  GLY C C   1 
ATOM   4776  O  O   . GLY C 1 32  ? 16.753  21.915  -13.084 1.00 28.03  ? 32  GLY C O   1 
ATOM   4777  N  N   . GLU C 1 33  ? 16.161  21.701  -15.253 1.00 31.38  ? 33  GLU C N   1 
ATOM   4778  C  CA  . GLU C 1 33  ? 16.927  20.478  -15.449 1.00 32.49  ? 33  GLU C CA  1 
ATOM   4779  C  C   . GLU C 1 33  ? 18.398  20.601  -15.012 1.00 31.01  ? 33  GLU C C   1 
ATOM   4780  O  O   . GLU C 1 33  ? 18.991  19.629  -14.516 1.00 26.80  ? 33  GLU C O   1 
ATOM   4781  C  CB  . GLU C 1 33  ? 16.827  20.014  -16.901 1.00 33.89  ? 33  GLU C CB  1 
ATOM   4782  C  CG  . GLU C 1 33  ? 15.454  19.542  -17.349 1.00 34.58  ? 33  GLU C CG  1 
ATOM   4783  C  CD  . GLU C 1 33  ? 14.500  20.631  -17.813 1.00 38.51  ? 33  GLU C CD  1 
ATOM   4784  O  OE1 . GLU C 1 33  ? 14.797  21.843  -17.735 1.00 34.22  ? 33  GLU C OE1 1 
ATOM   4785  O  OE2 . GLU C 1 33  ? 13.403  20.196  -18.245 1.00 44.53  ? 33  GLU C OE2 1 
ATOM   4786  N  N   . ASP C 1 34  ? 19.026  21.759  -15.250 1.00 31.00  ? 34  ASP C N   1 
ATOM   4787  C  CA  . ASP C 1 34  ? 20.441  21.927  -14.942 1.00 34.66  ? 34  ASP C CA  1 
ATOM   4788  C  C   . ASP C 1 34  ? 20.663  21.919  -13.432 1.00 37.63  ? 34  ASP C C   1 
ATOM   4789  O  O   . ASP C 1 34  ? 21.644  21.329  -12.936 1.00 34.24  ? 34  ASP C O   1 
ATOM   4790  C  CB  . ASP C 1 34  ? 21.015  23.210  -15.512 1.00 43.26  ? 34  ASP C CB  1 
ATOM   4791  C  CG  . ASP C 1 34  ? 21.260  23.169  -17.014 1.00 54.26  ? 34  ASP C CG  1 
ATOM   4792  O  OD1 . ASP C 1 34  ? 21.478  22.052  -17.525 1.00 50.70  ? 34  ASP C OD1 1 
ATOM   4793  O  OD2 . ASP C 1 34  ? 21.162  24.244  -17.660 1.00 58.59  ? 34  ASP C OD2 1 
ATOM   4794  N  N   . THR C 1 35  ? 19.751  22.591  -12.703 1.00 33.16  ? 35  THR C N   1 
ATOM   4795  C  CA  . THR C 1 35  ? 19.848  22.639  -11.261 1.00 29.14  ? 35  THR C CA  1 
ATOM   4796  C  C   . THR C 1 35  ? 19.747  21.231  -10.678 1.00 29.32  ? 35  THR C C   1 
ATOM   4797  O  O   . THR C 1 35  ? 20.533  20.881  -9.801  1.00 31.26  ? 35  THR C O   1 
ATOM   4798  C  CB  . THR C 1 35  ? 18.793  23.583  -10.705 1.00 28.15  ? 35  THR C CB  1 
ATOM   4799  O  OG1 . THR C 1 35  ? 19.242  24.854  -11.147 1.00 27.43  ? 35  THR C OG1 1 
ATOM   4800  C  CG2 . THR C 1 35  ? 18.855  23.679  -9.197  1.00 26.70  ? 35  THR C CG2 1 
ATOM   4801  N  N   . VAL C 1 36  ? 18.800  20.425  -11.176 1.00 29.37  ? 36  VAL C N   1 
ATOM   4802  C  CA  . VAL C 1 36  ? 18.623  19.052  -10.728 1.00 29.64  ? 36  VAL C CA  1 
ATOM   4803  C  C   . VAL C 1 36  ? 19.859  18.202  -11.031 1.00 32.38  ? 36  VAL C C   1 
ATOM   4804  O  O   . VAL C 1 36  ? 20.274  17.381  -10.216 1.00 34.68  ? 36  VAL C O   1 
ATOM   4805  C  CB  . VAL C 1 36  ? 17.388  18.433  -11.411 1.00 33.90  ? 36  VAL C CB  1 
ATOM   4806  C  CG1 . VAL C 1 36  ? 17.295  16.929  -11.149 1.00 36.04  ? 36  VAL C CG1 1 
ATOM   4807  C  CG2 . VAL C 1 36  ? 16.079  19.107  -11.019 1.00 33.53  ? 36  VAL C CG2 1 
ATOM   4808  N  N   . ARG C 1 37  ? 20.446  18.364  -12.220 1.00 35.94  ? 37  ARG C N   1 
ATOM   4809  C  CA  . ARG C 1 37  ? 21.639  17.609  -12.568 1.00 37.14  ? 37  ARG C CA  1 
ATOM   4810  C  C   . ARG C 1 37  ? 22.790  17.885  -11.604 1.00 34.46  ? 37  ARG C C   1 
ATOM   4811  O  O   . ARG C 1 37  ? 23.500  16.925  -11.240 1.00 36.78  ? 37  ARG C O   1 
ATOM   4812  C  CB  . ARG C 1 37  ? 22.152  17.854  -13.985 1.00 40.97  ? 37  ARG C CB  1 
ATOM   4813  C  CG  . ARG C 1 37  ? 21.706  16.822  -15.008 1.00 50.17  ? 37  ARG C CG  1 
ATOM   4814  C  CD  . ARG C 1 37  ? 22.641  16.705  -16.237 1.00 53.51  ? 37  ARG C CD  1 
ATOM   4815  N  NE  . ARG C 1 37  ? 21.660  16.880  -17.313 1.00 53.28  ? 37  ARG C NE  1 
ATOM   4816  C  CZ  . ARG C 1 37  ? 21.011  18.030  -17.613 1.00 57.81  ? 37  ARG C CZ  1 
ATOM   4817  N  NH1 . ARG C 1 37  ? 21.508  19.229  -17.307 1.00 50.75  ? 37  ARG C NH1 1 
ATOM   4818  N  NH2 . ARG C 1 37  ? 19.886  17.978  -18.326 1.00 67.27  ? 37  ARG C NH2 1 
ATOM   4819  N  N   . ASP C 1 38  ? 23.011  19.165  -11.228 1.00 32.53  ? 38  ASP C N   1 
ATOM   4820  C  CA  . ASP C 1 38  ? 24.081  19.483  -10.274 1.00 34.83  ? 38  ASP C CA  1 
ATOM   4821  C  C   . ASP C 1 38  ? 23.833  18.795  -8.937  1.00 30.48  ? 38  ASP C C   1 
ATOM   4822  O  O   . ASP C 1 38  ? 24.745  18.244  -8.334  1.00 28.87  ? 38  ASP C O   1 
ATOM   4823  C  CB  . ASP C 1 38  ? 24.192  20.938  -9.847  1.00 42.68  ? 38  ASP C CB  1 
ATOM   4824  C  CG  . ASP C 1 38  ? 24.867  21.870  -10.838 1.00 51.67  ? 38  ASP C CG  1 
ATOM   4825  O  OD1 . ASP C 1 38  ? 25.848  21.455  -11.481 1.00 57.27  ? 38  ASP C OD1 1 
ATOM   4826  O  OD2 . ASP C 1 38  ? 24.409  23.013  -10.944 1.00 61.01  ? 38  ASP C OD2 1 
ATOM   4827  N  N   . LEU C 1 39  ? 22.587  18.878  -8.466  1.00 29.51  ? 39  LEU C N   1 
ATOM   4828  C  CA  . LEU C 1 39  ? 22.236  18.294  -7.198  1.00 28.45  ? 39  LEU C CA  1 
ATOM   4829  C  C   . LEU C 1 39  ? 22.429  16.773  -7.232  1.00 28.65  ? 39  LEU C C   1 
ATOM   4830  O  O   . LEU C 1 39  ? 22.896  16.179  -6.253  1.00 27.79  ? 39  LEU C O   1 
ATOM   4831  C  CB  . LEU C 1 39  ? 20.801  18.603  -6.814  1.00 29.66  ? 39  LEU C CB  1 
ATOM   4832  C  CG  . LEU C 1 39  ? 20.502  17.764  -5.570  1.00 33.84  ? 39  LEU C CG  1 
ATOM   4833  C  CD1 . LEU C 1 39  ? 20.697  18.567  -4.315  1.00 37.80  ? 39  LEU C CD1 1 
ATOM   4834  C  CD2 . LEU C 1 39  ? 19.230  17.019  -5.611  1.00 37.94  ? 39  LEU C CD2 1 
ATOM   4835  N  N   . LEU C 1 40  ? 22.015  16.119  -8.322  1.00 25.54  ? 40  LEU C N   1 
ATOM   4836  C  CA  . LEU C 1 40  ? 22.168  14.682  -8.376  1.00 29.46  ? 40  LEU C CA  1 
ATOM   4837  C  C   . LEU C 1 40  ? 23.639  14.290  -8.177  1.00 30.71  ? 40  LEU C C   1 
ATOM   4838  O  O   . LEU C 1 40  ? 23.979  13.259  -7.591  1.00 30.12  ? 40  LEU C O   1 
ATOM   4839  C  CB  . LEU C 1 40  ? 21.603  14.143  -9.684  1.00 31.65  ? 40  LEU C CB  1 
ATOM   4840  C  CG  . LEU C 1 40  ? 20.086  14.200  -9.847  1.00 35.61  ? 40  LEU C CG  1 
ATOM   4841  C  CD1 . LEU C 1 40  ? 19.703  13.606  -11.184 1.00 33.23  ? 40  LEU C CD1 1 
ATOM   4842  C  CD2 . LEU C 1 40  ? 19.304  13.497  -8.747  1.00 38.59  ? 40  LEU C CD2 1 
ATOM   4843  N  N   . SER C 1 41  ? 24.559  15.098  -8.680  1.00 37.33  ? 41  SER C N   1 
ATOM   4844  C  CA  . SER C 1 41  ? 25.952  14.700  -8.555  1.00 43.74  ? 41  SER C CA  1 
ATOM   4845  C  C   . SER C 1 41  ? 26.451  14.957  -7.131  1.00 42.92  ? 41  SER C C   1 
ATOM   4846  O  O   . SER C 1 41  ? 27.519  14.494  -6.763  1.00 45.91  ? 41  SER C O   1 
ATOM   4847  C  CB  . SER C 1 41  ? 26.836  15.381  -9.570  1.00 44.30  ? 41  SER C CB  1 
ATOM   4848  O  OG  . SER C 1 41  ? 26.901  16.763  -9.260  1.00 43.05  ? 41  SER C OG  1 
ATOM   4849  N  N   . ASP C 1 42  ? 25.697  15.694  -6.318  1.00 34.28  ? 42  ASP C N   1 
ATOM   4850  C  CA  . ASP C 1 42  ? 26.166  16.043  -4.991  1.00 33.89  ? 42  ASP C CA  1 
ATOM   4851  C  C   . ASP C 1 42  ? 25.419  15.322  -3.869  1.00 30.48  ? 42  ASP C C   1 
ATOM   4852  O  O   . ASP C 1 42  ? 25.752  15.494  -2.688  1.00 24.41  ? 42  ASP C O   1 
ATOM   4853  C  CB  . ASP C 1 42  ? 26.000  17.525  -4.767  1.00 34.07  ? 42  ASP C CB  1 
ATOM   4854  C  CG  . ASP C 1 42  ? 26.996  18.388  -5.505  1.00 36.43  ? 42  ASP C CG  1 
ATOM   4855  O  OD1 . ASP C 1 42  ? 28.142  17.948  -5.595  1.00 41.92  ? 42  ASP C OD1 1 
ATOM   4856  O  OD2 . ASP C 1 42  ? 26.632  19.513  -5.871  1.00 37.76  ? 42  ASP C OD2 1 
ATOM   4857  N  N   . VAL C 1 43  ? 24.388  14.549  -4.224  1.00 29.41  ? 43  VAL C N   1 
ATOM   4858  C  CA  . VAL C 1 43  ? 23.472  14.109  -3.187  1.00 29.30  ? 43  VAL C CA  1 
ATOM   4859  C  C   . VAL C 1 43  ? 24.238  13.183  -2.221  1.00 29.50  ? 43  VAL C C   1 
ATOM   4860  O  O   . VAL C 1 43  ? 24.062  13.307  -1.015  1.00 26.45  ? 43  VAL C O   1 
ATOM   4861  C  CB  . VAL C 1 43  ? 22.186  13.508  -3.810  1.00 30.81  ? 43  VAL C CB  1 
ATOM   4862  C  CG1 . VAL C 1 43  ? 22.436  12.186  -4.492  1.00 38.01  ? 43  VAL C CG1 1 
ATOM   4863  C  CG2 . VAL C 1 43  ? 21.112  13.208  -2.796  1.00 33.31  ? 43  VAL C CG2 1 
ATOM   4864  N  N   . ALA C 1 44  ? 25.173  12.340  -2.722  1.00 26.60  ? 44  ALA C N   1 
ATOM   4865  C  CA  . ALA C 1 44  ? 25.944  11.450  -1.857  1.00 26.37  ? 44  ALA C CA  1 
ATOM   4866  C  C   . ALA C 1 44  ? 26.805  12.262  -0.904  1.00 26.33  ? 44  ALA C C   1 
ATOM   4867  O  O   . ALA C 1 44  ? 26.950  11.904  0.257   1.00 25.56  ? 44  ALA C O   1 
ATOM   4868  C  CB  . ALA C 1 44  ? 26.803  10.503  -2.635  1.00 24.36  ? 44  ALA C CB  1 
ATOM   4869  N  N   . SER C 1 45  ? 27.333  13.399  -1.361  1.00 26.09  ? 45  SER C N   1 
ATOM   4870  C  CA  . SER C 1 45  ? 28.225  14.125  -0.484  1.00 26.92  ? 45  SER C CA  1 
ATOM   4871  C  C   . SER C 1 45  ? 27.429  14.882  0.557   1.00 23.97  ? 45  SER C C   1 
ATOM   4872  O  O   . SER C 1 45  ? 27.938  15.080  1.656   1.00 22.93  ? 45  SER C O   1 
ATOM   4873  C  CB  . SER C 1 45  ? 29.260  14.975  -1.187  1.00 27.76  ? 45  SER C CB  1 
ATOM   4874  O  OG  . SER C 1 45  ? 28.654  15.723  -2.203  1.00 35.09  ? 45  SER C OG  1 
ATOM   4875  N  N   . LEU C 1 46  ? 26.178  15.241  0.246   1.00 23.08  ? 46  LEU C N   1 
ATOM   4876  C  CA  . LEU C 1 46  ? 25.344  15.857  1.271   1.00 23.45  ? 46  LEU C CA  1 
ATOM   4877  C  C   . LEU C 1 46  ? 24.924  14.833  2.329   1.00 22.04  ? 46  LEU C C   1 
ATOM   4878  O  O   . LEU C 1 46  ? 24.751  15.163  3.481   1.00 21.65  ? 46  LEU C O   1 
ATOM   4879  C  CB  . LEU C 1 46  ? 24.155  16.492  0.565   1.00 26.73  ? 46  LEU C CB  1 
ATOM   4880  C  CG  . LEU C 1 46  ? 24.484  17.719  -0.268  1.00 27.28  ? 46  LEU C CG  1 
ATOM   4881  C  CD1 . LEU C 1 46  ? 23.280  18.087  -1.112  1.00 29.63  ? 46  LEU C CD1 1 
ATOM   4882  C  CD2 . LEU C 1 46  ? 24.913  18.871  0.612   1.00 28.04  ? 46  LEU C CD2 1 
ATOM   4883  N  N   . GLU C 1 47  ? 24.719  13.587  1.928   1.00 22.48  ? 47  GLU C N   1 
ATOM   4884  C  CA  . GLU C 1 47  ? 24.386  12.523  2.850   1.00 23.49  ? 47  GLU C CA  1 
ATOM   4885  C  C   . GLU C 1 47  ? 25.535  12.353  3.836   1.00 23.37  ? 47  GLU C C   1 
ATOM   4886  O  O   . GLU C 1 47  ? 25.300  12.188  5.023   1.00 21.48  ? 47  GLU C O   1 
ATOM   4887  C  CB  . GLU C 1 47  ? 24.132  11.313  1.954   1.00 27.09  ? 47  GLU C CB  1 
ATOM   4888  C  CG  . GLU C 1 47  ? 23.593  10.107  2.682   1.00 30.02  ? 47  GLU C CG  1 
ATOM   4889  C  CD  . GLU C 1 47  ? 23.649  8.943   1.735   1.00 32.76  ? 47  GLU C CD  1 
ATOM   4890  O  OE1 . GLU C 1 47  ? 23.186  9.117   0.615   1.00 35.58  ? 47  GLU C OE1 1 
ATOM   4891  O  OE2 . GLU C 1 47  ? 24.214  7.916   2.098   1.00 36.28  ? 47  GLU C OE2 1 
ATOM   4892  N  N   . ARG C 1 48  ? 26.784  12.464  3.362   1.00 24.19  ? 48  ARG C N   1 
ATOM   4893  C  CA  . ARG C 1 48  ? 27.927  12.390  4.263   1.00 22.99  ? 48  ARG C CA  1 
ATOM   4894  C  C   . ARG C 1 48  ? 28.025  13.615  5.157   1.00 23.26  ? 48  ARG C C   1 
ATOM   4895  O  O   . ARG C 1 48  ? 28.285  13.508  6.343   1.00 22.78  ? 48  ARG C O   1 
ATOM   4896  C  CB  . ARG C 1 48  ? 29.255  12.193  3.546   1.00 22.58  ? 48  ARG C CB  1 
ATOM   4897  C  CG  . ARG C 1 48  ? 29.190  10.847  2.853   1.00 25.21  ? 48  ARG C CG  1 
ATOM   4898  C  CD  . ARG C 1 48  ? 30.514  10.279  2.423   1.00 29.41  ? 48  ARG C CD  1 
ATOM   4899  N  NE  . ARG C 1 48  ? 31.198  11.219  1.530   1.00 34.38  ? 48  ARG C NE  1 
ATOM   4900  C  CZ  . ARG C 1 48  ? 30.996  11.334  0.214   1.00 39.58  ? 48  ARG C CZ  1 
ATOM   4901  N  NH1 . ARG C 1 48  ? 30.248  10.446  -0.445  1.00 34.53  ? 48  ARG C NH1 1 
ATOM   4902  N  NH2 . ARG C 1 48  ? 31.574  12.346  -0.437  1.00 43.66  ? 48  ARG C NH2 1 
ATOM   4903  N  N   . ALA C 1 49  ? 27.840  14.793  4.585   1.00 23.05  ? 49  ALA C N   1 
ATOM   4904  C  CA  . ALA C 1 49  ? 27.966  15.997  5.377   1.00 23.82  ? 49  ALA C CA  1 
ATOM   4905  C  C   . ALA C 1 49  ? 27.044  15.910  6.581   1.00 25.15  ? 49  ALA C C   1 
ATOM   4906  O  O   . ALA C 1 49  ? 27.475  16.143  7.700   1.00 32.72  ? 49  ALA C O   1 
ATOM   4907  C  CB  . ALA C 1 49  ? 27.654  17.213  4.534   1.00 23.70  ? 49  ALA C CB  1 
ATOM   4908  N  N   . VAL C 1 50  ? 25.782  15.551  6.351   1.00 23.95  ? 50  VAL C N   1 
ATOM   4909  C  CA  . VAL C 1 50  ? 24.792  15.540  7.420   1.00 26.38  ? 50  VAL C CA  1 
ATOM   4910  C  C   . VAL C 1 50  ? 24.985  14.321  8.314   1.00 25.20  ? 50  VAL C C   1 
ATOM   4911  O  O   . VAL C 1 50  ? 24.809  14.436  9.533   1.00 25.30  ? 50  VAL C O   1 
ATOM   4912  C  CB  . VAL C 1 50  ? 23.347  15.528  6.876   1.00 29.39  ? 50  VAL C CB  1 
ATOM   4913  C  CG1 . VAL C 1 50  ? 22.293  15.326  7.973   1.00 27.66  ? 50  VAL C CG1 1 
ATOM   4914  C  CG2 . VAL C 1 50  ? 23.070  16.776  6.049   1.00 31.35  ? 50  VAL C CG2 1 
ATOM   4915  N  N   . GLY C 1 51  ? 25.278  13.162  7.704   1.00 22.64  ? 51  GLY C N   1 
ATOM   4916  C  CA  . GLY C 1 51  ? 25.192  11.924  8.455   1.00 25.89  ? 51  GLY C CA  1 
ATOM   4917  C  C   . GLY C 1 51  ? 26.465  11.578  9.233   1.00 29.68  ? 51  GLY C C   1 
ATOM   4918  O  O   . GLY C 1 51  ? 26.391  10.943  10.279  1.00 28.10  ? 51  GLY C O   1 
ATOM   4919  N  N   . PHE C 1 52  ? 27.643  11.902  8.681   1.00 39.37  ? 52  PHE C N   1 
ATOM   4920  C  CA  . PHE C 1 52  ? 28.900  11.389  9.216   1.00 34.05  ? 52  PHE C CA  1 
ATOM   4921  C  C   . PHE C 1 52  ? 29.021  11.726  10.701  1.00 36.31  ? 52  PHE C C   1 
ATOM   4922  O  O   . PHE C 1 52  ? 29.325  10.836  11.485  1.00 36.28  ? 52  PHE C O   1 
ATOM   4923  C  CB  . PHE C 1 52  ? 30.070  11.920  8.397   1.00 36.42  ? 52  PHE C CB  1 
ATOM   4924  C  CG  . PHE C 1 52  ? 31.347  11.366  8.985   1.00 33.37  ? 52  PHE C CG  1 
ATOM   4925  C  CD1 . PHE C 1 52  ? 31.684  10.044  8.748   1.00 32.04  ? 52  PHE C CD1 1 
ATOM   4926  C  CD2 . PHE C 1 52  ? 32.138  12.139  9.841   1.00 32.01  ? 52  PHE C CD2 1 
ATOM   4927  C  CE1 . PHE C 1 52  ? 32.802  9.490   9.369   1.00 32.56  ? 52  PHE C CE1 1 
ATOM   4928  C  CE2 . PHE C 1 52  ? 33.244  11.586  10.449  1.00 30.40  ? 52  PHE C CE2 1 
ATOM   4929  C  CZ  . PHE C 1 52  ? 33.571  10.265  10.214  1.00 31.14  ? 52  PHE C CZ  1 
ATOM   4930  N  N   . ARG C 1 53  ? 28.726  12.973  11.103  1.00 41.96  ? 53  ARG C N   1 
ATOM   4931  C  CA  . ARG C 1 53  ? 28.881  13.390  12.494  1.00 41.21  ? 53  ARG C CA  1 
ATOM   4932  C  C   . ARG C 1 53  ? 27.998  12.612  13.471  1.00 40.95  ? 53  ARG C C   1 
ATOM   4933  O  O   . ARG C 1 53  ? 28.261  12.679  14.676  1.00 44.07  ? 53  ARG C O   1 
ATOM   4934  C  CB  . ARG C 1 53  ? 28.621  14.884  12.744  1.00 48.25  ? 53  ARG C CB  1 
ATOM   4935  C  CG  . ARG C 1 53  ? 27.226  15.477  12.585  1.00 48.60  ? 53  ARG C CG  1 
ATOM   4936  C  CD  . ARG C 1 53  ? 27.156  16.938  13.093  1.00 52.09  ? 53  ARG C CD  1 
ATOM   4937  N  NE  . ARG C 1 53  ? 26.387  17.807  12.191  1.00 49.85  ? 53  ARG C NE  1 
ATOM   4938  C  CZ  . ARG C 1 53  ? 26.564  17.777  10.877  1.00 50.60  ? 53  ARG C CZ  1 
ATOM   4939  N  NH1 . ARG C 1 53  ? 27.555  17.058  10.381  1.00 66.18  ? 53  ARG C NH1 1 
ATOM   4940  N  NH2 . ARG C 1 53  ? 25.760  18.413  10.050  1.00 47.55  ? 53  ARG C NH2 1 
ATOM   4941  N  N   . ALA C 1 54  ? 26.963  11.907  12.973  1.00 38.96  ? 54  ALA C N   1 
ATOM   4942  C  CA  . ALA C 1 54  ? 26.061  11.149  13.837  1.00 39.44  ? 54  ALA C CA  1 
ATOM   4943  C  C   . ALA C 1 54  ? 26.341  9.671   13.728  1.00 37.85  ? 54  ALA C C   1 
ATOM   4944  O  O   . ALA C 1 54  ? 25.540  8.888   14.189  1.00 41.52  ? 54  ALA C O   1 
ATOM   4945  C  CB  . ALA C 1 54  ? 24.608  11.391  13.510  1.00 37.64  ? 54  ALA C CB  1 
ATOM   4946  N  N   . GLN C 1 55  ? 27.466  9.310   13.122  1.00 45.71  ? 55  GLN C N   1 
ATOM   4947  C  CA  . GLN C 1 55  ? 27.909  7.923   13.094  1.00 58.29  ? 55  GLN C CA  1 
ATOM   4948  C  C   . GLN C 1 55  ? 28.256  7.419   14.491  1.00 56.84  ? 55  GLN C C   1 
ATOM   4949  O  O   . GLN C 1 55  ? 28.663  8.193   15.355  1.00 56.74  ? 55  GLN C O   1 
ATOM   4950  C  CB  . GLN C 1 55  ? 29.119  7.675   12.188  1.00 63.96  ? 55  GLN C CB  1 
ATOM   4951  C  CG  . GLN C 1 55  ? 28.808  7.771   10.694  1.00 60.40  ? 55  GLN C CG  1 
ATOM   4952  C  CD  . GLN C 1 55  ? 27.660  6.892   10.224  1.00 67.78  ? 55  GLN C CD  1 
ATOM   4953  O  OE1 . GLN C 1 55  ? 26.763  6.485   10.977  1.00 79.58  ? 55  GLN C OE1 1 
ATOM   4954  N  NE2 . GLN C 1 55  ? 27.661  6.592   8.934   1.00 66.72  ? 55  GLN C NE2 1 
ATOM   4955  N  N   . PRO C 1 56  ? 28.034  6.107   14.744  1.00 65.35  ? 56  PRO C N   1 
ATOM   4956  C  CA  . PRO C 1 56  ? 27.392  5.211   13.767  1.00 69.06  ? 56  PRO C CA  1 
ATOM   4957  C  C   . PRO C 1 56  ? 25.886  4.927   13.954  1.00 65.73  ? 56  PRO C C   1 
ATOM   4958  O  O   . PRO C 1 56  ? 25.249  4.286   13.122  1.00 52.06  ? 56  PRO C O   1 
ATOM   4959  C  CB  . PRO C 1 56  ? 28.295  3.963   13.948  1.00 66.79  ? 56  PRO C CB  1 
ATOM   4960  C  CG  . PRO C 1 56  ? 28.882  4.076   15.361  1.00 63.52  ? 56  PRO C CG  1 
ATOM   4961  C  CD  . PRO C 1 56  ? 28.402  5.387   15.970  1.00 64.40  ? 56  PRO C CD  1 
ATOM   4962  N  N   . ASP C 1 57  ? 25.306  5.443   15.051  1.00 72.84  ? 57  ASP C N   1 
ATOM   4963  C  CA  . ASP C 1 57  ? 23.897  5.333   15.409  1.00 69.80  ? 57  ASP C CA  1 
ATOM   4964  C  C   . ASP C 1 57  ? 22.956  5.824   14.302  1.00 59.78  ? 57  ASP C C   1 
ATOM   4965  O  O   . ASP C 1 57  ? 21.824  5.344   14.211  1.00 62.00  ? 57  ASP C O   1 
ATOM   4966  C  CB  . ASP C 1 57  ? 23.575  6.221   16.609  1.00 89.41  ? 57  ASP C CB  1 
ATOM   4967  C  CG  . ASP C 1 57  ? 24.758  6.880   17.322  1.00 107.29 ? 57  ASP C CG  1 
ATOM   4968  O  OD1 . ASP C 1 57  ? 25.360  7.858   16.766  1.00 100.39 ? 57  ASP C OD1 1 
ATOM   4969  O  OD2 . ASP C 1 57  ? 25.091  6.399   18.422  1.00 110.29 ? 57  ASP C OD2 1 
ATOM   4970  N  N   . GLY C 1 58  ? 23.404  6.833   13.528  1.00 49.67  ? 58  GLY C N   1 
ATOM   4971  C  CA  . GLY C 1 58  ? 22.543  7.648   12.667  1.00 42.95  ? 58  GLY C CA  1 
ATOM   4972  C  C   . GLY C 1 58  ? 21.844  6.851   11.553  1.00 36.48  ? 58  GLY C C   1 
ATOM   4973  O  O   . GLY C 1 58  ? 20.640  6.967   11.362  1.00 31.12  ? 58  GLY C O   1 
ATOM   4974  N  N   . ARG C 1 59  ? 22.615  6.039   10.827  1.00 33.23  ? 59  ARG C N   1 
ATOM   4975  C  CA  . ARG C 1 59  ? 22.100  5.137   9.806   1.00 34.86  ? 59  ARG C CA  1 
ATOM   4976  C  C   . ARG C 1 59  ? 21.360  5.940   8.732   1.00 33.38  ? 59  ARG C C   1 
ATOM   4977  O  O   . ARG C 1 59  ? 20.459  5.406   8.099   1.00 32.11  ? 59  ARG C O   1 
ATOM   4978  C  CB  . ARG C 1 59  ? 21.278  3.992   10.415  1.00 36.83  ? 59  ARG C CB  1 
ATOM   4979  C  CG  . ARG C 1 59  ? 22.118  2.954   11.159  1.00 41.96  ? 59  ARG C CG  1 
ATOM   4980  C  CD  . ARG C 1 59  ? 21.502  1.566   11.346  1.00 42.85  ? 59  ARG C CD  1 
ATOM   4981  N  NE  . ARG C 1 59  ? 20.816  1.388   12.631  1.00 42.45  ? 59  ARG C NE  1 
ATOM   4982  N  N   . LEU C 1 60  ? 21.807  7.180   8.460   1.00 31.11  ? 60  LEU C N   1 
ATOM   4983  C  CA  . LEU C 1 60  ? 21.178  8.042   7.465   1.00 27.28  ? 60  LEU C CA  1 
ATOM   4984  C  C   . LEU C 1 60  ? 21.509  7.551   6.073   1.00 26.33  ? 60  LEU C C   1 
ATOM   4985  O  O   . LEU C 1 60  ? 22.663  7.335   5.812   1.00 28.19  ? 60  LEU C O   1 
ATOM   4986  C  CB  . LEU C 1 60  ? 21.696  9.460   7.617   1.00 26.91  ? 60  LEU C CB  1 
ATOM   4987  C  CG  . LEU C 1 60  ? 21.067  10.511  6.695   1.00 27.95  ? 60  LEU C CG  1 
ATOM   4988  C  CD1 . LEU C 1 60  ? 19.565  10.739  6.932   1.00 28.50  ? 60  LEU C CD1 1 
ATOM   4989  C  CD2 . LEU C 1 60  ? 21.799  11.837  6.884   1.00 28.71  ? 60  LEU C CD2 1 
ATOM   4990  N  N   . SER C 1 61  ? 20.507  7.408   5.201   1.00 28.01  ? 61  SER C N   1 
ATOM   4991  C  CA  . SER C 1 61  ? 20.660  6.943   3.825   1.00 24.54  ? 61  SER C CA  1 
ATOM   4992  C  C   . SER C 1 61  ? 19.654  7.724   2.998   1.00 22.77  ? 61  SER C C   1 
ATOM   4993  O  O   . SER C 1 61  ? 18.548  7.973   3.470   1.00 24.21  ? 61  SER C O   1 
ATOM   4994  C  CB  . SER C 1 61  ? 20.450  5.437   3.754   1.00 23.31  ? 61  SER C CB  1 
ATOM   4995  O  OG  . SER C 1 61  ? 19.139  5.076   3.409   1.00 28.66  ? 61  SER C OG  1 
ATOM   4996  N  N   . CYS C 1 62  ? 20.057  8.204   1.828   1.00 22.09  ? 62  CYS C N   1 
ATOM   4997  C  CA  . CYS C 1 62  ? 19.109  8.798   0.912   1.00 20.53  ? 62  CYS C CA  1 
ATOM   4998  C  C   . CYS C 1 62  ? 19.078  8.000   -0.378  1.00 19.72  ? 62  CYS C C   1 
ATOM   4999  O  O   . CYS C 1 62  ? 20.109  7.713   -0.904  1.00 22.38  ? 62  CYS C O   1 
ATOM   5000  C  CB  . CYS C 1 62  ? 19.491  10.218  0.579   1.00 21.17  ? 62  CYS C CB  1 
ATOM   5001  S  SG  . CYS C 1 62  ? 18.357  10.891  -0.655  1.00 25.46  ? 62  CYS C SG  1 
ATOM   5002  N  N   . VAL C 1 63  ? 17.937  7.548   -0.854  1.00 20.61  ? 63  VAL C N   1 
ATOM   5003  C  CA  . VAL C 1 63  ? 17.893  6.901   -2.167  1.00 22.68  ? 63  VAL C CA  1 
ATOM   5004  C  C   . VAL C 1 63  ? 17.134  7.815   -3.126  1.00 24.31  ? 63  VAL C C   1 
ATOM   5005  O  O   . VAL C 1 63  ? 16.054  8.301   -2.798  1.00 26.78  ? 63  VAL C O   1 
ATOM   5006  C  CB  . VAL C 1 63  ? 17.218  5.532   -2.127  1.00 23.95  ? 63  VAL C CB  1 
ATOM   5007  C  CG1 . VAL C 1 63  ? 16.988  4.976   -3.524  1.00 24.94  ? 63  VAL C CG1 1 
ATOM   5008  C  CG2 . VAL C 1 63  ? 17.985  4.575   -1.228  1.00 25.72  ? 63  VAL C CG2 1 
ATOM   5009  N  N   . THR C 1 64  ? 17.735  8.098   -4.276  1.00 25.26  ? 64  THR C N   1 
ATOM   5010  C  CA  . THR C 1 64  ? 17.206  9.070   -5.205  1.00 23.14  ? 64  THR C CA  1 
ATOM   5011  C  C   . THR C 1 64  ? 16.678  8.315   -6.406  1.00 24.29  ? 64  THR C C   1 
ATOM   5012  O  O   . THR C 1 64  ? 17.396  7.532   -6.999  1.00 27.11  ? 64  THR C O   1 
ATOM   5013  C  CB  . THR C 1 64  ? 18.326  9.980   -5.659  1.00 25.34  ? 64  THR C CB  1 
ATOM   5014  O  OG1 . THR C 1 64  ? 18.895  10.588  -4.515  1.00 26.43  ? 64  THR C OG1 1 
ATOM   5015  C  CG2 . THR C 1 64  ? 17.804  11.093  -6.543  1.00 29.98  ? 64  THR C CG2 1 
ATOM   5016  N  N   . GLY C 1 65  ? 15.437  8.579   -6.771  1.00 23.72  ? 65  GLY C N   1 
ATOM   5017  C  CA  . GLY C 1 65  ? 14.791  7.910   -7.884  1.00 25.19  ? 65  GLY C CA  1 
ATOM   5018  C  C   . GLY C 1 65  ? 14.363  8.928   -8.945  1.00 25.01  ? 65  GLY C C   1 
ATOM   5019  O  O   . GLY C 1 65  ? 14.054  10.081  -8.632  1.00 22.45  ? 65  GLY C O   1 
ATOM   5020  N  N   . ILE C 1 66  ? 14.384  8.488   -10.211 1.00 26.99  ? 66  ILE C N   1 
ATOM   5021  C  CA  . ILE C 1 66  ? 14.006  9.339   -11.320 1.00 26.77  ? 66  ILE C CA  1 
ATOM   5022  C  C   . ILE C 1 66  ? 12.876  8.664   -12.097 1.00 25.44  ? 66  ILE C C   1 
ATOM   5023  O  O   . ILE C 1 66  ? 12.903  7.457   -12.367 1.00 20.90  ? 66  ILE C O   1 
ATOM   5024  C  CB  . ILE C 1 66  ? 15.244  9.638   -12.174 1.00 28.41  ? 66  ILE C CB  1 
ATOM   5025  C  CG1 . ILE C 1 66  ? 16.350  10.249  -11.294 1.00 30.44  ? 66  ILE C CG1 1 
ATOM   5026  C  CG2 . ILE C 1 66  ? 14.898  10.518  -13.388 1.00 29.36  ? 66  ILE C CG2 1 
ATOM   5027  C  CD1 . ILE C 1 66  ? 17.748  10.021  -11.831 1.00 32.30  ? 66  ILE C CD1 1 
ATOM   5028  N  N   . GLY C 1 67  ? 11.877  9.478   -12.434 1.00 24.05  ? 67  GLY C N   1 
ATOM   5029  C  CA  . GLY C 1 67  ? 10.748  8.977   -13.193 1.00 30.39  ? 67  GLY C CA  1 
ATOM   5030  C  C   . GLY C 1 67  ? 11.010  8.886   -14.703 1.00 30.93  ? 67  GLY C C   1 
ATOM   5031  O  O   . GLY C 1 67  ? 12.048  9.300   -15.217 1.00 27.09  ? 67  GLY C O   1 
ATOM   5032  N  N   . SER C 1 68  ? 10.003  8.331   -15.382 1.00 30.50  ? 68  SER C N   1 
ATOM   5033  C  CA  . SER C 1 68  ? 10.044  8.048   -16.802 1.00 32.84  ? 68  SER C CA  1 
ATOM   5034  C  C   . SER C 1 68  ? 10.178  9.328   -17.623 1.00 26.53  ? 68  SER C C   1 
ATOM   5035  O  O   . SER C 1 68  ? 11.135  9.466   -18.357 1.00 25.87  ? 68  SER C O   1 
ATOM   5036  C  CB  . SER C 1 68  ? 8.849   7.244   -17.216 1.00 34.73  ? 68  SER C CB  1 
ATOM   5037  O  OG  . SER C 1 68  ? 9.164   6.602   -18.437 1.00 33.56  ? 68  SER C OG  1 
ATOM   5038  N  N   . GLU C 1 69  ? 9.291   10.289  -17.473 1.00 23.28  ? 69  GLU C N   1 
ATOM   5039  C  CA  . GLU C 1 69  ? 9.401   11.478  -18.299 1.00 27.32  ? 69  GLU C CA  1 
ATOM   5040  C  C   . GLU C 1 69  ? 10.529  12.397  -17.864 1.00 31.10  ? 69  GLU C C   1 
ATOM   5041  O  O   . GLU C 1 69  ? 11.120  13.110  -18.681 1.00 33.35  ? 69  GLU C O   1 
ATOM   5042  C  CB  . GLU C 1 69  ? 8.104   12.263  -18.314 1.00 33.32  ? 69  GLU C CB  1 
ATOM   5043  C  CG  . GLU C 1 69  ? 6.961   11.415  -18.867 1.00 44.68  ? 69  GLU C CG  1 
ATOM   5044  C  CD  . GLU C 1 69  ? 5.777   12.033  -18.196 1.00 57.94  ? 69  GLU C CD  1 
ATOM   5045  O  OE1 . GLU C 1 69  ? 5.693   13.295  -18.278 1.00 57.91  ? 69  GLU C OE1 1 
ATOM   5046  O  OE2 . GLU C 1 69  ? 5.057   11.260  -17.522 1.00 67.81  ? 69  GLU C OE2 1 
ATOM   5047  N  N   . ALA C 1 70  ? 10.847  12.397  -16.575 1.00 33.11  ? 70  ALA C N   1 
ATOM   5048  C  CA  . ALA C 1 70  ? 12.000  13.167  -16.121 1.00 36.59  ? 70  ALA C CA  1 
ATOM   5049  C  C   . ALA C 1 70  ? 13.292  12.637  -16.752 1.00 32.07  ? 70  ALA C C   1 
ATOM   5050  O  O   . ALA C 1 70  ? 14.210  13.396  -17.065 1.00 28.28  ? 70  ALA C O   1 
ATOM   5051  C  CB  . ALA C 1 70  ? 12.076  13.100  -14.613 1.00 38.39  ? 70  ALA C CB  1 
ATOM   5052  N  N   . TRP C 1 71  ? 13.373  11.310  -16.900 1.00 26.79  ? 71  TRP C N   1 
ATOM   5053  C  CA  . TRP C 1 71  ? 14.566  10.681  -17.432 1.00 28.81  ? 71  TRP C CA  1 
ATOM   5054  C  C   . TRP C 1 71  ? 14.956  11.276  -18.786 1.00 31.65  ? 71  TRP C C   1 
ATOM   5055  O  O   . TRP C 1 71  ? 16.125  11.591  -19.052 1.00 28.77  ? 71  TRP C O   1 
ATOM   5056  C  CB  . TRP C 1 71  ? 14.385  9.171   -17.540 1.00 27.82  ? 71  TRP C CB  1 
ATOM   5057  C  CG  . TRP C 1 71  ? 15.697  8.522   -17.832 1.00 28.23  ? 71  TRP C CG  1 
ATOM   5058  C  CD1 . TRP C 1 71  ? 16.268  8.419   -19.050 1.00 29.40  ? 71  TRP C CD1 1 
ATOM   5059  C  CD2 . TRP C 1 71  ? 16.625  7.988   -16.873 1.00 32.55  ? 71  TRP C CD2 1 
ATOM   5060  N  NE1 . TRP C 1 71  ? 17.500  7.851   -18.920 1.00 32.95  ? 71  TRP C NE1 1 
ATOM   5061  C  CE2 . TRP C 1 71  ? 17.743  7.567   -17.604 1.00 33.73  ? 71  TRP C CE2 1 
ATOM   5062  C  CE3 . TRP C 1 71  ? 16.603  7.796   -15.485 1.00 40.19  ? 71  TRP C CE3 1 
ATOM   5063  C  CZ2 . TRP C 1 71  ? 18.847  6.981   -16.996 1.00 35.74  ? 71  TRP C CZ2 1 
ATOM   5064  C  CZ3 . TRP C 1 71  ? 17.687  7.203   -14.877 1.00 43.51  ? 71  TRP C CZ3 1 
ATOM   5065  C  CH2 . TRP C 1 71  ? 18.810  6.840   -15.630 1.00 43.58  ? 71  TRP C CH2 1 
ATOM   5066  N  N   . ASP C 1 72  ? 13.934  11.447  -19.621 1.00 35.05  ? 72  ASP C N   1 
ATOM   5067  C  CA  . ASP C 1 72  ? 14.099  11.934  -20.980 1.00 34.27  ? 72  ASP C CA  1 
ATOM   5068  C  C   . ASP C 1 72  ? 14.456  13.403  -20.963 1.00 33.54  ? 72  ASP C C   1 
ATOM   5069  O  O   . ASP C 1 72  ? 15.167  13.817  -21.844 1.00 35.06  ? 72  ASP C O   1 
ATOM   5070  C  CB  . ASP C 1 72  ? 12.891  11.612  -21.840 1.00 37.02  ? 72  ASP C CB  1 
ATOM   5071  C  CG  . ASP C 1 72  ? 12.763  10.120  -22.120 1.00 40.97  ? 72  ASP C CG  1 
ATOM   5072  O  OD1 . ASP C 1 72  ? 13.795  9.406   -22.014 1.00 40.21  ? 72  ASP C OD1 1 
ATOM   5073  O  OD2 . ASP C 1 72  ? 11.635  9.659   -22.410 1.00 42.23  ? 72  ASP C OD2 1 
ATOM   5074  N  N   . ARG C 1 73  ? 14.022  14.173  -19.959 1.00 34.52  ? 73  ARG C N   1 
ATOM   5075  C  CA  . ARG C 1 73  ? 14.394  15.572  -19.891 1.00 30.10  ? 73  ARG C CA  1 
ATOM   5076  C  C   . ARG C 1 73  ? 15.800  15.739  -19.345 1.00 34.46  ? 73  ARG C C   1 
ATOM   5077  O  O   . ARG C 1 73  ? 16.331  16.827  -19.438 1.00 38.19  ? 73  ARG C O   1 
ATOM   5078  C  CB  . ARG C 1 73  ? 13.457  16.349  -18.978 1.00 28.94  ? 73  ARG C CB  1 
ATOM   5079  C  CG  . ARG C 1 73  ? 12.010  16.211  -19.426 1.00 30.04  ? 73  ARG C CG  1 
ATOM   5080  C  CD  . ARG C 1 73  ? 11.003  16.682  -18.398 1.00 31.89  ? 73  ARG C CD  1 
ATOM   5081  N  NE  . ARG C 1 73  ? 11.309  18.038  -17.908 1.00 33.37  ? 73  ARG C NE  1 
ATOM   5082  C  CZ  . ARG C 1 73  ? 10.687  18.631  -16.872 1.00 29.91  ? 73  ARG C CZ  1 
ATOM   5083  N  NH1 . ARG C 1 73  ? 9.790   17.944  -16.136 1.00 28.55  ? 73  ARG C NH1 1 
ATOM   5084  N  NH2 . ARG C 1 73  ? 10.980  19.897  -16.595 1.00 25.91  ? 73  ARG C NH2 1 
ATOM   5085  N  N   . LEU C 1 74  ? 16.374  14.734  -18.674 1.00 39.11  ? 74  LEU C N   1 
ATOM   5086  C  CA  . LEU C 1 74  ? 17.591  14.979  -17.905 1.00 45.96  ? 74  LEU C CA  1 
ATOM   5087  C  C   . LEU C 1 74  ? 18.807  14.407  -18.620 1.00 42.86  ? 74  LEU C C   1 
ATOM   5088  O  O   . LEU C 1 74  ? 19.913  14.891  -18.473 1.00 36.80  ? 74  LEU C O   1 
ATOM   5089  C  CB  . LEU C 1 74  ? 17.522  14.380  -16.494 1.00 49.71  ? 74  LEU C CB  1 
ATOM   5090  C  CG  . LEU C 1 74  ? 16.659  15.124  -15.471 1.00 48.50  ? 74  LEU C CG  1 
ATOM   5091  C  CD1 . LEU C 1 74  ? 16.545  14.290  -14.225 1.00 47.31  ? 74  LEU C CD1 1 
ATOM   5092  C  CD2 . LEU C 1 74  ? 17.249  16.466  -15.143 1.00 48.52  ? 74  LEU C CD2 1 
ATOM   5093  N  N   . PHE C 1 75  ? 18.600  13.286  -19.296 1.00 44.60  ? 75  PHE C N   1 
ATOM   5094  C  CA  . PHE C 1 75  ? 19.675  12.485  -19.847 1.00 42.14  ? 75  PHE C CA  1 
ATOM   5095  C  C   . PHE C 1 75  ? 19.324  12.188  -21.296 1.00 45.25  ? 75  PHE C C   1 
ATOM   5096  O  O   . PHE C 1 75  ? 18.152  12.096  -21.646 1.00 45.10  ? 75  PHE C O   1 
ATOM   5097  C  CB  . PHE C 1 75  ? 19.702  11.155  -19.102 1.00 40.95  ? 75  PHE C CB  1 
ATOM   5098  C  CG  . PHE C 1 75  ? 19.798  11.313  -17.598 1.00 39.88  ? 75  PHE C CG  1 
ATOM   5099  C  CD1 . PHE C 1 75  ? 20.830  12.046  -17.032 1.00 38.32  ? 75  PHE C CD1 1 
ATOM   5100  C  CD2 . PHE C 1 75  ? 18.833  10.776  -16.755 1.00 43.17  ? 75  PHE C CD2 1 
ATOM   5101  C  CE1 . PHE C 1 75  ? 20.924  12.208  -15.649 1.00 38.46  ? 75  PHE C CE1 1 
ATOM   5102  C  CE2 . PHE C 1 75  ? 18.924  10.953  -15.373 1.00 44.46  ? 75  PHE C CE2 1 
ATOM   5103  C  CZ  . PHE C 1 75  ? 19.966  11.666  -14.821 1.00 39.27  ? 75  PHE C CZ  1 
ATOM   5104  N  N   . SER C 1 76  ? 20.310  12.047  -22.167 1.00 57.28  ? 76  SER C N   1 
ATOM   5105  C  CA  . SER C 1 76  ? 20.020  11.298  -23.382 1.00 64.98  ? 76  SER C CA  1 
ATOM   5106  C  C   . SER C 1 76  ? 21.025  10.174  -23.400 1.00 54.29  ? 76  SER C C   1 
ATOM   5107  O  O   . SER C 1 76  ? 21.958  10.165  -22.621 1.00 60.63  ? 76  SER C O   1 
ATOM   5108  C  CB  . SER C 1 76  ? 20.030  12.097  -24.654 1.00 68.17  ? 76  SER C CB  1 
ATOM   5109  O  OG  . SER C 1 76  ? 21.112  13.010  -24.598 1.00 84.46  ? 76  SER C OG  1 
ATOM   5110  N  N   . GLY C 1 77  ? 20.772  9.205   -24.246 1.00 47.06  ? 77  GLY C N   1 
ATOM   5111  C  CA  . GLY C 1 77  ? 21.467  7.953   -24.160 1.00 44.95  ? 77  GLY C CA  1 
ATOM   5112  C  C   . GLY C 1 77  ? 20.412  6.930   -23.802 1.00 42.30  ? 77  GLY C C   1 
ATOM   5113  O  O   . GLY C 1 77  ? 19.223  7.221   -23.890 1.00 38.22  ? 77  GLY C O   1 
ATOM   5114  N  N   . ALA C 1 78  ? 20.892  5.774   -23.341 1.00 46.31  ? 78  ALA C N   1 
ATOM   5115  C  CA  . ALA C 1 78  ? 20.078  4.652   -22.917 1.00 44.62  ? 78  ALA C CA  1 
ATOM   5116  C  C   . ALA C 1 78  ? 19.069  5.085   -21.844 1.00 48.92  ? 78  ALA C C   1 
ATOM   5117  O  O   . ALA C 1 78  ? 19.319  5.975   -21.018 1.00 45.40  ? 78  ALA C O   1 
ATOM   5118  C  CB  . ALA C 1 78  ? 20.989  3.529   -22.427 1.00 42.86  ? 78  ALA C CB  1 
ATOM   5119  N  N   . ARG C 1 79  ? 17.890  4.461   -21.929 1.00 43.77  ? 79  ARG C N   1 
ATOM   5120  C  CA  . ARG C 1 79  ? 16.941  4.381   -20.849 1.00 43.68  ? 79  ARG C CA  1 
ATOM   5121  C  C   . ARG C 1 79  ? 17.060  3.017   -20.173 1.00 44.89  ? 79  ARG C C   1 
ATOM   5122  O  O   . ARG C 1 79  ? 17.281  2.008   -20.825 1.00 41.69  ? 79  ARG C O   1 
ATOM   5123  C  CB  . ARG C 1 79  ? 15.545  4.530   -21.442 1.00 42.82  ? 79  ARG C CB  1 
ATOM   5124  C  CG  . ARG C 1 79  ? 15.262  5.980   -21.801 1.00 41.57  ? 79  ARG C CG  1 
ATOM   5125  C  CD  . ARG C 1 79  ? 13.843  6.072   -22.331 1.00 43.86  ? 79  ARG C CD  1 
ATOM   5126  N  NE  . ARG C 1 79  ? 12.889  5.403   -21.435 1.00 40.61  ? 79  ARG C NE  1 
ATOM   5127  C  CZ  . ARG C 1 79  ? 12.121  6.071   -20.601 1.00 40.37  ? 79  ARG C CZ  1 
ATOM   5128  N  NH1 . ARG C 1 79  ? 12.105  7.381   -20.625 1.00 42.02  ? 79  ARG C NH1 1 
ATOM   5129  N  NH2 . ARG C 1 79  ? 11.379  5.453   -19.716 1.00 41.34  ? 79  ARG C NH2 1 
ATOM   5130  N  N   . PRO C 1 80  ? 16.913  2.920   -18.836 1.00 44.62  ? 80  PRO C N   1 
ATOM   5131  C  CA  . PRO C 1 80  ? 16.747  1.604   -18.216 1.00 40.69  ? 80  PRO C CA  1 
ATOM   5132  C  C   . PRO C 1 80  ? 15.551  0.913   -18.877 1.00 37.90  ? 80  PRO C C   1 
ATOM   5133  O  O   . PRO C 1 80  ? 14.534  1.547   -19.159 1.00 36.91  ? 80  PRO C O   1 
ATOM   5134  C  CB  . PRO C 1 80  ? 16.507  1.941   -16.755 1.00 41.50  ? 80  PRO C CB  1 
ATOM   5135  C  CG  . PRO C 1 80  ? 17.103  3.339   -16.582 1.00 43.82  ? 80  PRO C CG  1 
ATOM   5136  C  CD  . PRO C 1 80  ? 16.894  4.059   -17.889 1.00 45.14  ? 80  PRO C CD  1 
ATOM   5137  N  N   . ALA C 1 81  ? 15.682  -0.396  -19.091 1.00 34.96  ? 81  ALA C N   1 
ATOM   5138  C  CA  . ALA C 1 81  ? 14.718  -1.185  -19.844 1.00 36.41  ? 81  ALA C CA  1 
ATOM   5139  C  C   . ALA C 1 81  ? 13.276  -1.061  -19.319 1.00 38.00  ? 81  ALA C C   1 
ATOM   5140  O  O   . ALA C 1 81  ? 12.316  -0.970  -20.097 1.00 32.63  ? 81  ALA C O   1 
ATOM   5141  C  CB  . ALA C 1 81  ? 15.181  -2.625  -19.838 1.00 34.46  ? 81  ALA C CB  1 
ATOM   5142  N  N   . GLY C 1 82  ? 13.113  -1.077  -17.993 1.00 37.03  ? 82  GLY C N   1 
ATOM   5143  C  CA  . GLY C 1 82  ? 11.794  -1.221  -17.391 1.00 39.25  ? 82  GLY C CA  1 
ATOM   5144  C  C   . GLY C 1 82  ? 11.090  0.108   -17.110 1.00 35.58  ? 82  GLY C C   1 
ATOM   5145  O  O   . GLY C 1 82  ? 9.987   0.111   -16.605 1.00 37.59  ? 82  GLY C O   1 
ATOM   5146  N  N   . LEU C 1 83  ? 11.706  1.239   -17.431 1.00 32.89  ? 83  LEU C N   1 
ATOM   5147  C  CA  . LEU C 1 83  ? 11.210  2.509   -16.934 1.00 31.54  ? 83  LEU C CA  1 
ATOM   5148  C  C   . LEU C 1 83  ? 10.059  3.026   -17.785 1.00 29.28  ? 83  LEU C C   1 
ATOM   5149  O  O   . LEU C 1 83  ? 10.249  3.396   -18.902 1.00 34.36  ? 83  LEU C O   1 
ATOM   5150  C  CB  . LEU C 1 83  ? 12.380  3.494   -16.866 1.00 34.72  ? 83  LEU C CB  1 
ATOM   5151  C  CG  . LEU C 1 83  ? 12.045  4.880   -16.313 1.00 35.97  ? 83  LEU C CG  1 
ATOM   5152  C  CD1 . LEU C 1 83  ? 11.550  4.776   -14.863 1.00 38.95  ? 83  LEU C CD1 1 
ATOM   5153  C  CD2 . LEU C 1 83  ? 13.234  5.766   -16.447 1.00 35.85  ? 83  LEU C CD2 1 
ATOM   5154  N  N   . HIS C 1 84  ? 8.884   3.188   -17.204 1.00 30.39  ? 84  HIS C N   1 
ATOM   5155  C  CA  . HIS C 1 84  ? 7.755   3.818   -17.857 1.00 27.73  ? 84  HIS C CA  1 
ATOM   5156  C  C   . HIS C 1 84  ? 6.968   4.551   -16.787 1.00 26.91  ? 84  HIS C C   1 
ATOM   5157  O  O   . HIS C 1 84  ? 7.282   4.427   -15.601 1.00 32.64  ? 84  HIS C O   1 
ATOM   5158  C  CB  . HIS C 1 84  ? 6.883   2.739   -18.476 1.00 27.99  ? 84  HIS C CB  1 
ATOM   5159  C  CG  . HIS C 1 84  ? 6.665   1.529   -17.630 1.00 29.13  ? 84  HIS C CG  1 
ATOM   5160  N  ND1 . HIS C 1 84  ? 7.475   0.413   -17.756 1.00 35.70  ? 84  HIS C ND1 1 
ATOM   5161  C  CD2 . HIS C 1 84  ? 5.725   1.218   -16.711 1.00 29.26  ? 84  HIS C CD2 1 
ATOM   5162  C  CE1 . HIS C 1 84  ? 7.033   -0.536  -16.906 1.00 37.49  ? 84  HIS C CE1 1 
ATOM   5163  N  NE2 . HIS C 1 84  ? 5.969   -0.061  -16.257 1.00 35.09  ? 84  HIS C NE2 1 
ATOM   5164  N  N   . PRO C 1 85  ? 5.912   5.311   -17.120 1.00 26.24  ? 85  PRO C N   1 
ATOM   5165  C  CA  . PRO C 1 85  ? 5.040   5.891   -16.091 1.00 28.18  ? 85  PRO C CA  1 
ATOM   5166  C  C   . PRO C 1 85  ? 4.303   4.794   -15.333 1.00 28.83  ? 85  PRO C C   1 
ATOM   5167  O  O   . PRO C 1 85  ? 4.145   3.712   -15.858 1.00 35.00  ? 85  PRO C O   1 
ATOM   5168  C  CB  . PRO C 1 85  ? 4.091   6.811   -16.883 1.00 25.24  ? 85  PRO C CB  1 
ATOM   5169  C  CG  . PRO C 1 85  ? 4.920   7.125   -18.119 1.00 25.95  ? 85  PRO C CG  1 
ATOM   5170  C  CD  . PRO C 1 85  ? 5.538   5.752   -18.454 1.00 26.05  ? 85  PRO C CD  1 
ATOM   5171  N  N   . PHE C 1 86  ? 3.898   5.056   -14.101 1.00 28.54  ? 86  PHE C N   1 
ATOM   5172  C  CA  . PHE C 1 86  ? 3.027   4.145   -13.368 1.00 31.50  ? 86  PHE C CA  1 
ATOM   5173  C  C   . PHE C 1 86  ? 1.716   3.872   -14.137 1.00 32.59  ? 86  PHE C C   1 
ATOM   5174  O  O   . PHE C 1 86  ? 1.056   4.821   -14.556 1.00 32.61  ? 86  PHE C O   1 
ATOM   5175  C  CB  . PHE C 1 86  ? 2.782   4.805   -12.005 1.00 28.65  ? 86  PHE C CB  1 
ATOM   5176  C  CG  . PHE C 1 86  ? 1.931   3.969   -11.065 1.00 29.36  ? 86  PHE C CG  1 
ATOM   5177  C  CD1 . PHE C 1 86  ? 2.501   3.012   -10.265 1.00 29.09  ? 86  PHE C CD1 1 
ATOM   5178  C  CD2 . PHE C 1 86  ? 0.567   4.164   -10.974 1.00 30.37  ? 86  PHE C CD2 1 
ATOM   5179  C  CE1 . PHE C 1 86  ? 1.709   2.281   -9.397  1.00 33.11  ? 86  PHE C CE1 1 
ATOM   5180  C  CE2 . PHE C 1 86  ? -0.213  3.386   -10.149 1.00 28.77  ? 86  PHE C CE2 1 
ATOM   5181  C  CZ  . PHE C 1 86  ? 0.356   2.466   -9.358  1.00 30.06  ? 86  PHE C CZ  1 
ATOM   5182  N  N   . ARG C 1 87  ? 1.350   2.575   -14.300 1.00 32.59  ? 87  ARG C N   1 
ATOM   5183  C  CA  . ARG C 1 87  ? 0.166   2.135   -15.040 1.00 29.86  ? 87  ARG C CA  1 
ATOM   5184  C  C   . ARG C 1 87  ? -0.986  2.141   -14.039 1.00 34.81  ? 87  ARG C C   1 
ATOM   5185  O  O   . ARG C 1 87  ? -0.990  1.312   -13.121 1.00 35.42  ? 87  ARG C O   1 
ATOM   5186  C  CB  . ARG C 1 87  ? 0.278   0.788   -15.790 1.00 23.88  ? 87  ARG C CB  1 
ATOM   5187  N  N   . GLU C 1 88  ? -1.898  3.128   -14.202 1.00 37.44  ? 88  GLU C N   1 
ATOM   5188  C  CA  . GLU C 1 88  ? -3.147  3.273   -13.464 1.00 36.93  ? 88  GLU C CA  1 
ATOM   5189  C  C   . GLU C 1 88  ? -3.886  1.947   -13.515 1.00 35.41  ? 88  GLU C C   1 
ATOM   5190  O  O   . GLU C 1 88  ? -3.781  1.265   -14.512 1.00 40.83  ? 88  GLU C O   1 
ATOM   5191  C  CB  . GLU C 1 88  ? -3.872  4.422   -14.157 1.00 41.59  ? 88  GLU C CB  1 
ATOM   5192  C  CG  . GLU C 1 88  ? -5.003  5.039   -13.343 1.00 57.58  ? 88  GLU C CG  1 
ATOM   5193  C  CD  . GLU C 1 88  ? -5.065  6.534   -13.617 1.00 68.97  ? 88  GLU C CD  1 
ATOM   5194  O  OE1 . GLU C 1 88  ? -4.806  7.331   -12.694 1.00 61.06  ? 88  GLU C OE1 1 
ATOM   5195  O  OE2 . GLU C 1 88  ? -5.312  6.904   -14.787 1.00 100.47 ? 88  GLU C OE2 1 
ATOM   5196  N  N   . LEU C 1 89  ? -4.528  1.518   -12.428 1.00 37.89  ? 89  LEU C N   1 
ATOM   5197  C  CA  . LEU C 1 89  ? -5.347  0.300   -12.439 1.00 39.04  ? 89  LEU C CA  1 
ATOM   5198  C  C   . LEU C 1 89  ? -6.811  0.654   -12.120 1.00 42.44  ? 89  LEU C C   1 
ATOM   5199  O  O   . LEU C 1 89  ? -7.144  1.271   -11.105 1.00 39.45  ? 89  LEU C O   1 
ATOM   5200  C  CB  . LEU C 1 89  ? -4.840  -0.835  -11.549 1.00 35.36  ? 89  LEU C CB  1 
ATOM   5201  C  CG  . LEU C 1 89  ? -3.403  -1.315  -11.790 1.00 38.00  ? 89  LEU C CG  1 
ATOM   5202  C  CD1 . LEU C 1 89  ? -2.982  -2.496  -10.942 1.00 37.26  ? 89  LEU C CD1 1 
ATOM   5203  C  CD2 . LEU C 1 89  ? -3.200  -1.758  -13.201 1.00 44.14  ? 89  LEU C CD2 1 
ATOM   5204  N  N   . ASP C 1 90  ? -7.695  0.297   -13.063 1.00 53.03  ? 90  ASP C N   1 
ATOM   5205  C  CA  . ASP C 1 90  ? -9.107  0.614   -12.990 1.00 50.57  ? 90  ASP C CA  1 
ATOM   5206  C  C   . ASP C 1 90  ? -9.836  -0.681  -12.706 1.00 44.64  ? 90  ASP C C   1 
ATOM   5207  O  O   . ASP C 1 90  ? -10.209 -1.417  -13.594 1.00 44.87  ? 90  ASP C O   1 
ATOM   5208  C  CB  . ASP C 1 90  ? -9.595  1.278   -14.256 1.00 52.17  ? 90  ASP C CB  1 
ATOM   5209  C  CG  . ASP C 1 90  ? -10.434 2.471   -13.908 1.00 61.38  ? 90  ASP C CG  1 
ATOM   5210  O  OD1 . ASP C 1 90  ? -11.394 2.277   -13.102 1.00 58.57  ? 90  ASP C OD1 1 
ATOM   5211  O  OD2 . ASP C 1 90  ? -10.005 3.549   -14.340 1.00 73.35  ? 90  ASP C OD2 1 
ATOM   5212  N  N   . GLY C 1 91  ? -9.923  -1.024  -11.444 1.00 44.59  ? 91  GLY C N   1 
ATOM   5213  C  CA  . GLY C 1 91  ? -10.596 -2.248  -11.090 1.00 50.71  ? 91  GLY C CA  1 
ATOM   5214  C  C   . GLY C 1 91  ? -12.108 -2.026  -11.034 1.00 48.19  ? 91  GLY C C   1 
ATOM   5215  O  O   . GLY C 1 91  ? -12.616 -0.892  -10.972 1.00 39.62  ? 91  GLY C O   1 
ATOM   5216  N  N   . PRO C 1 92  ? -12.859 -3.148  -11.042 1.00 43.23  ? 92  PRO C N   1 
ATOM   5217  C  CA  . PRO C 1 92  ? -14.285 -3.118  -10.760 1.00 39.30  ? 92  PRO C CA  1 
ATOM   5218  C  C   . PRO C 1 92  ? -14.689 -2.258  -9.569  1.00 38.81  ? 92  PRO C C   1 
ATOM   5219  O  O   . PRO C 1 92  ? -15.705 -1.574  -9.604  1.00 38.96  ? 92  PRO C O   1 
ATOM   5220  C  CB  . PRO C 1 92  ? -14.600 -4.606  -10.533 1.00 37.95  ? 92  PRO C CB  1 
ATOM   5221  C  CG  . PRO C 1 92  ? -13.279 -5.373  -10.593 1.00 40.11  ? 92  PRO C CG  1 
ATOM   5222  C  CD  . PRO C 1 92  ? -12.357 -4.494  -11.372 1.00 40.44  ? 92  PRO C CD  1 
ATOM   5223  N  N   . VAL C 1 93  ? -13.906 -2.313  -8.489  1.00 43.74  ? 93  VAL C N   1 
ATOM   5224  C  CA  . VAL C 1 93  ? -14.272 -1.673  -7.217  1.00 44.25  ? 93  VAL C CA  1 
ATOM   5225  C  C   . VAL C 1 93  ? -13.250 -0.593  -6.836  1.00 36.52  ? 93  VAL C C   1 
ATOM   5226  O  O   . VAL C 1 93  ? -13.615 0.494   -6.424  1.00 31.67  ? 93  VAL C O   1 
ATOM   5227  C  CB  . VAL C 1 93  ? -14.435 -2.719  -6.076  1.00 41.43  ? 93  VAL C CB  1 
ATOM   5228  C  CG1 . VAL C 1 93  ? -14.699 -2.059  -4.737  1.00 39.72  ? 93  VAL C CG1 1 
ATOM   5229  C  CG2 . VAL C 1 93  ? -15.544 -3.721  -6.361  1.00 41.74  ? 93  VAL C CG2 1 
ATOM   5230  N  N   . HIS C 1 94  ? -11.964 -0.950  -6.923  1.00 36.31  ? 94  HIS C N   1 
ATOM   5231  C  CA  . HIS C 1 94  ? -10.864 -0.199  -6.352  1.00 32.90  ? 94  HIS C CA  1 
ATOM   5232  C  C   . HIS C 1 94  ? -9.914  0.219   -7.470  1.00 35.63  ? 94  HIS C C   1 
ATOM   5233  O  O   . HIS C 1 94  ? -9.623  -0.583  -8.368  1.00 37.14  ? 94  HIS C O   1 
ATOM   5234  C  CB  . HIS C 1 94  ? -10.093 -1.072  -5.357  1.00 29.81  ? 94  HIS C CB  1 
ATOM   5235  C  CG  . HIS C 1 94  ? -10.847 -1.460  -4.121  1.00 27.75  ? 94  HIS C CG  1 
ATOM   5236  N  ND1 . HIS C 1 94  ? -11.323 -0.554  -3.173  1.00 25.75  ? 94  HIS C ND1 1 
ATOM   5237  C  CD2 . HIS C 1 94  ? -11.197 -2.716  -3.713  1.00 26.45  ? 94  HIS C CD2 1 
ATOM   5238  C  CE1 . HIS C 1 94  ? -11.949 -1.244  -2.214  1.00 27.58  ? 94  HIS C CE1 1 
ATOM   5239  N  NE2 . HIS C 1 94  ? -11.887 -2.562  -2.526  1.00 30.44  ? 94  HIS C NE2 1 
ATOM   5240  N  N   . ARG C 1 95  ? -9.382  1.443   -7.311  1.00 34.75  ? 95  ARG C N   1 
ATOM   5241  C  CA  . ARG C 1 95  ? -8.594  2.159   -8.297  1.00 38.27  ? 95  ARG C CA  1 
ATOM   5242  C  C   . ARG C 1 95  ? -7.204  2.492   -7.726  1.00 34.19  ? 95  ARG C C   1 
ATOM   5243  O  O   . ARG C 1 95  ? -7.064  3.152   -6.698  1.00 29.12  ? 95  ARG C O   1 
ATOM   5244  C  CB  . ARG C 1 95  ? -9.522  3.339   -8.613  1.00 47.45  ? 95  ARG C CB  1 
ATOM   5245  C  CG  . ARG C 1 95  ? -9.078  4.401   -9.601  1.00 57.19  ? 95  ARG C CG  1 
ATOM   5246  C  CD  . ARG C 1 95  ? -10.255 5.162   -10.215 1.00 69.10  ? 95  ARG C CD  1 
ATOM   5247  N  NE  . ARG C 1 95  ? -9.918  5.183   -11.645 1.00 94.56  ? 95  ARG C NE  1 
ATOM   5248  C  CZ  . ARG C 1 95  ? -8.814  5.752   -12.145 1.00 99.32  ? 95  ARG C CZ  1 
ATOM   5249  N  NH1 . ARG C 1 95  ? -8.261  6.752   -11.493 1.00 98.44  ? 95  ARG C NH1 1 
ATOM   5250  N  NH2 . ARG C 1 95  ? -8.304  5.384   -13.310 1.00 91.33  ? 95  ARG C NH2 1 
ATOM   5251  N  N   . ALA C 1 96  ? -6.170  2.024   -8.422  1.00 31.23  ? 96  ALA C N   1 
ATOM   5252  C  CA  . ALA C 1 96  ? -4.810  2.470   -8.213  1.00 30.87  ? 96  ALA C CA  1 
ATOM   5253  C  C   . ALA C 1 96  ? -4.496  3.664   -9.125  1.00 30.99  ? 96  ALA C C   1 
ATOM   5254  O  O   . ALA C 1 96  ? -4.197  3.508   -10.290 1.00 27.40  ? 96  ALA C O   1 
ATOM   5255  C  CB  . ALA C 1 96  ? -3.881  1.309   -8.477  1.00 28.54  ? 96  ALA C CB  1 
ATOM   5256  N  N   . VAL C 1 97  ? -4.511  4.873   -8.587  1.00 33.85  ? 97  VAL C N   1 
ATOM   5257  C  CA  . VAL C 1 97  ? -4.227  6.053   -9.376  1.00 32.07  ? 97  VAL C CA  1 
ATOM   5258  C  C   . VAL C 1 97  ? -2.729  6.228   -9.560  1.00 31.56  ? 97  VAL C C   1 
ATOM   5259  O  O   . VAL C 1 97  ? -1.925  5.683   -8.786  1.00 37.64  ? 97  VAL C O   1 
ATOM   5260  C  CB  . VAL C 1 97  ? -4.785  7.297   -8.670  1.00 39.63  ? 97  VAL C CB  1 
ATOM   5261  C  CG1 . VAL C 1 97  ? -6.282  7.197   -8.415  1.00 43.59  ? 97  VAL C CG1 1 
ATOM   5262  C  CG2 . VAL C 1 97  ? -4.087  7.576   -7.349  1.00 42.29  ? 97  VAL C CG2 1 
ATOM   5263  N  N   . ALA C 1 98  ? -2.436  7.046   -10.586 1.00 30.29  ? 98  ALA C N   1 
ATOM   5264  C  CA  . ALA C 1 98  ? -1.110  7.480   -10.994 1.00 28.32  ? 98  ALA C CA  1 
ATOM   5265  C  C   . ALA C 1 98  ? -1.055  8.975   -10.826 1.00 26.61  ? 98  ALA C C   1 
ATOM   5266  O  O   . ALA C 1 98  ? -1.891  9.648   -11.372 1.00 29.53  ? 98  ALA C O   1 
ATOM   5267  C  CB  . ALA C 1 98  ? -0.808  7.184   -12.440 1.00 29.51  ? 98  ALA C CB  1 
ATOM   5268  N  N   . THR C 1 99  ? -0.065  9.474   -10.096 1.00 26.38  ? 99  THR C N   1 
ATOM   5269  C  CA  . THR C 1 99  ? 0.022   10.882  -9.765  1.00 23.46  ? 99  THR C CA  1 
ATOM   5270  C  C   . THR C 1 99  ? 1.392   11.374  -10.155 1.00 22.70  ? 99  THR C C   1 
ATOM   5271  O  O   . THR C 1 99  ? 2.258   10.573  -10.392 1.00 23.93  ? 99  THR C O   1 
ATOM   5272  C  CB  . THR C 1 99  ? -0.275  11.074  -8.284  1.00 24.76  ? 99  THR C CB  1 
ATOM   5273  O  OG1 . THR C 1 99  ? 0.579   10.255  -7.482  1.00 23.61  ? 99  THR C OG1 1 
ATOM   5274  C  CG2 . THR C 1 99  ? -1.719  10.709  -8.003  1.00 22.65  ? 99  THR C CG2 1 
ATOM   5275  N  N   . PRO C 1 100 ? 1.608   12.682  -10.362 1.00 24.05  ? 100 PRO C N   1 
ATOM   5276  C  CA  . PRO C 1 100 ? 2.872   13.182  -10.915 1.00 25.57  ? 100 PRO C CA  1 
ATOM   5277  C  C   . PRO C 1 100 ? 4.004   12.999  -9.925  1.00 25.44  ? 100 PRO C C   1 
ATOM   5278  O  O   . PRO C 1 100 ? 3.753   13.130  -8.740  1.00 28.45  ? 100 PRO C O   1 
ATOM   5279  C  CB  . PRO C 1 100 ? 2.624   14.673  -11.151 1.00 26.27  ? 100 PRO C CB  1 
ATOM   5280  C  CG  . PRO C 1 100 ? 1.140   14.782  -11.140 1.00 26.23  ? 100 PRO C CG  1 
ATOM   5281  C  CD  . PRO C 1 100 ? 0.647   13.750  -10.124 1.00 24.14  ? 100 PRO C CD  1 
ATOM   5282  N  N   . GLY C 1 101 ? 5.215   12.784  -10.447 1.00 25.26  ? 101 GLY C N   1 
ATOM   5283  C  CA  . GLY C 1 101 ? 6.425   12.536  -9.672  1.00 26.39  ? 101 GLY C CA  1 
ATOM   5284  C  C   . GLY C 1 101 ? 7.662   12.409  -10.564 1.00 26.93  ? 101 GLY C C   1 
ATOM   5285  O  O   . GLY C 1 101 ? 7.825   11.418  -11.231 1.00 37.17  ? 101 GLY C O   1 
ATOM   5286  N  N   . ASP C 1 102 ? 8.581   13.358  -10.566 1.00 26.31  ? 102 ASP C N   1 
ATOM   5287  C  CA  . ASP C 1 102 ? 9.755   13.222  -11.399 1.00 27.17  ? 102 ASP C CA  1 
ATOM   5288  C  C   . ASP C 1 102 ? 10.945  12.699  -10.603 1.00 28.54  ? 102 ASP C C   1 
ATOM   5289  O  O   . ASP C 1 102 ? 11.806  11.990  -11.135 1.00 27.17  ? 102 ASP C O   1 
ATOM   5290  C  CB  . ASP C 1 102 ? 10.090  14.569  -12.010 1.00 30.40  ? 102 ASP C CB  1 
ATOM   5291  C  CG  . ASP C 1 102 ? 9.109   15.059  -13.071 1.00 30.80  ? 102 ASP C CG  1 
ATOM   5292  O  OD1 . ASP C 1 102 ? 8.466   14.209  -13.722 1.00 25.94  ? 102 ASP C OD1 1 
ATOM   5293  O  OD2 . ASP C 1 102 ? 8.992   16.293  -13.222 1.00 29.87  ? 102 ASP C OD2 1 
ATOM   5294  N  N   . LEU C 1 103 ? 11.020  13.114  -9.335  1.00 29.32  ? 103 LEU C N   1 
ATOM   5295  C  CA  . LEU C 1 103 ? 12.129  12.781  -8.452  1.00 23.63  ? 103 LEU C CA  1 
ATOM   5296  C  C   . LEU C 1 103 ? 11.536  12.232  -7.172  1.00 21.90  ? 103 LEU C C   1 
ATOM   5297  O  O   . LEU C 1 103 ? 10.544  12.790  -6.709  1.00 22.07  ? 103 LEU C O   1 
ATOM   5298  C  CB  . LEU C 1 103 ? 12.985  13.991  -8.116  1.00 23.56  ? 103 LEU C CB  1 
ATOM   5299  C  CG  . LEU C 1 103 ? 13.810  14.593  -9.248  1.00 25.55  ? 103 LEU C CG  1 
ATOM   5300  C  CD1 . LEU C 1 103 ? 14.637  15.773  -8.730  1.00 23.67  ? 103 LEU C CD1 1 
ATOM   5301  C  CD2 . LEU C 1 103 ? 14.700  13.528  -9.838  1.00 27.30  ? 103 LEU C CD2 1 
ATOM   5302  N  N   . LEU C 1 104 ? 12.133  11.146  -6.661  1.00 19.43  ? 104 LEU C N   1 
ATOM   5303  C  CA  . LEU C 1 104 ? 11.891  10.623  -5.337  1.00 19.58  ? 104 LEU C CA  1 
ATOM   5304  C  C   . LEU C 1 104 ? 13.149  10.727  -4.489  1.00 22.33  ? 104 LEU C C   1 
ATOM   5305  O  O   . LEU C 1 104 ? 14.215  10.274  -4.912  1.00 21.80  ? 104 LEU C O   1 
ATOM   5306  C  CB  . LEU C 1 104 ? 11.506  9.166   -5.444  1.00 20.81  ? 104 LEU C CB  1 
ATOM   5307  C  CG  . LEU C 1 104 ? 11.491  8.379   -4.130  1.00 22.35  ? 104 LEU C CG  1 
ATOM   5308  C  CD1 . LEU C 1 104 ? 10.370  8.820   -3.255  1.00 21.69  ? 104 LEU C CD1 1 
ATOM   5309  C  CD2 . LEU C 1 104 ? 11.323  6.899   -4.367  1.00 24.46  ? 104 LEU C CD2 1 
ATOM   5310  N  N   . PHE C 1 105 ? 12.987  11.242  -3.254  1.00 22.52  ? 105 PHE C N   1 
ATOM   5311  C  CA  . PHE C 1 105 ? 14.024  11.123  -2.247  1.00 21.51  ? 105 PHE C CA  1 
ATOM   5312  C  C   . PHE C 1 105 ? 13.461  10.293  -1.122  1.00 19.49  ? 105 PHE C C   1 
ATOM   5313  O  O   . PHE C 1 105 ? 12.502  10.709  -0.526  1.00 19.07  ? 105 PHE C O   1 
ATOM   5314  C  CB  . PHE C 1 105 ? 14.502  12.485  -1.756  1.00 21.49  ? 105 PHE C CB  1 
ATOM   5315  C  CG  . PHE C 1 105 ? 15.015  13.357  -2.875  1.00 19.56  ? 105 PHE C CG  1 
ATOM   5316  C  CD1 . PHE C 1 105 ? 16.303  13.168  -3.343  1.00 21.03  ? 105 PHE C CD1 1 
ATOM   5317  C  CD2 . PHE C 1 105 ? 14.228  14.324  -3.452  1.00 18.97  ? 105 PHE C CD2 1 
ATOM   5318  C  CE1 . PHE C 1 105 ? 16.824  13.945  -4.359  1.00 19.78  ? 105 PHE C CE1 1 
ATOM   5319  C  CE2 . PHE C 1 105 ? 14.758  15.121  -4.436  1.00 20.25  ? 105 PHE C CE2 1 
ATOM   5320  C  CZ  . PHE C 1 105 ? 16.047  14.930  -4.888  1.00 21.37  ? 105 PHE C CZ  1 
ATOM   5321  N  N   . HIS C 1 106 ? 14.027  9.102   -0.917  1.00 20.48  ? 106 HIS C N   1 
ATOM   5322  C  CA  . HIS C 1 106 ? 13.631  8.193   0.135   1.00 18.83  ? 106 HIS C CA  1 
ATOM   5323  C  C   . HIS C 1 106 ? 14.728  8.254   1.181   1.00 18.62  ? 106 HIS C C   1 
ATOM   5324  O  O   . HIS C 1 106 ? 15.786  7.643   1.015   1.00 19.46  ? 106 HIS C O   1 
ATOM   5325  C  CB  . HIS C 1 106 ? 13.447  6.782   -0.433  1.00 19.71  ? 106 HIS C CB  1 
ATOM   5326  C  CG  . HIS C 1 106 ? 13.039  5.794   0.596   1.00 19.07  ? 106 HIS C CG  1 
ATOM   5327  N  ND1 . HIS C 1 106 ? 13.204  4.438   0.431   1.00 18.64  ? 106 HIS C ND1 1 
ATOM   5328  C  CD2 . HIS C 1 106 ? 12.478  5.967   1.793   1.00 19.92  ? 106 HIS C CD2 1 
ATOM   5329  C  CE1 . HIS C 1 106 ? 12.748  3.825   1.512   1.00 19.75  ? 106 HIS C CE1 1 
ATOM   5330  N  NE2 . HIS C 1 106 ? 12.320  4.726   2.370   1.00 20.28  ? 106 HIS C NE2 1 
ATOM   5331  N  N   . ILE C 1 107 ? 14.485  9.085   2.195   1.00 20.41  ? 107 ILE C N   1 
ATOM   5332  C  CA  . ILE C 1 107 ? 15.439  9.341   3.264   1.00 20.20  ? 107 ILE C CA  1 
ATOM   5333  C  C   . ILE C 1 107 ? 15.095  8.549   4.536   1.00 22.31  ? 107 ILE C C   1 
ATOM   5334  O  O   . ILE C 1 107 ? 13.952  8.557   5.006   1.00 20.22  ? 107 ILE C O   1 
ATOM   5335  C  CB  . ILE C 1 107 ? 15.489  10.837  3.531   1.00 20.90  ? 107 ILE C CB  1 
ATOM   5336  C  CG1 . ILE C 1 107 ? 15.769  11.607  2.244   1.00 23.92  ? 107 ILE C CG1 1 
ATOM   5337  C  CG2 . ILE C 1 107 ? 16.518  11.124  4.621   1.00 19.75  ? 107 ILE C CG2 1 
ATOM   5338  C  CD1 . ILE C 1 107 ? 15.636  13.116  2.369   1.00 26.26  ? 107 ILE C CD1 1 
ATOM   5339  N  N   . ARG C 1 108 ? 16.105  7.855   5.092   1.00 23.85  ? 108 ARG C N   1 
ATOM   5340  C  CA  . ARG C 1 108 ? 15.890  6.952   6.214   1.00 25.33  ? 108 ARG C CA  1 
ATOM   5341  C  C   . ARG C 1 108 ? 17.011  7.128   7.215   1.00 24.20  ? 108 ARG C C   1 
ATOM   5342  O  O   . ARG C 1 108 ? 18.139  7.378   6.851   1.00 22.45  ? 108 ARG C O   1 
ATOM   5343  C  CB  . ARG C 1 108 ? 15.841  5.460   5.862   1.00 25.58  ? 108 ARG C CB  1 
ATOM   5344  C  CG  . ARG C 1 108 ? 14.579  5.098   5.095   1.00 26.14  ? 108 ARG C CG  1 
ATOM   5345  C  CD  . ARG C 1 108 ? 14.649  3.695   4.570   1.00 25.86  ? 108 ARG C CD  1 
ATOM   5346  N  NE  . ARG C 1 108 ? 15.591  3.567   3.448   1.00 28.02  ? 108 ARG C NE  1 
ATOM   5347  C  CZ  . ARG C 1 108 ? 15.662  2.482   2.698   1.00 25.55  ? 108 ARG C CZ  1 
ATOM   5348  N  NH1 . ARG C 1 108 ? 14.825  1.513   2.939   1.00 26.78  ? 108 ARG C NH1 1 
ATOM   5349  N  NH2 . ARG C 1 108 ? 16.502  2.364   1.694   1.00 28.78  ? 108 ARG C NH2 1 
ATOM   5350  N  N   . ALA C 1 109 ? 16.657  6.983   8.481   1.00 27.91  ? 109 ALA C N   1 
ATOM   5351  C  CA  . ALA C 1 109 ? 17.619  7.089   9.563   1.00 28.87  ? 109 ALA C CA  1 
ATOM   5352  C  C   . ALA C 1 109 ? 16.989  6.558   10.857  1.00 26.52  ? 109 ALA C C   1 
ATOM   5353  O  O   . ALA C 1 109 ? 15.792  6.287   10.927  1.00 20.92  ? 109 ALA C O   1 
ATOM   5354  C  CB  . ALA C 1 109 ? 18.075  8.533   9.727   1.00 25.23  ? 109 ALA C CB  1 
ATOM   5355  N  N   . SER C 1 110 ? 17.814  6.471   11.901  1.00 24.76  ? 110 SER C N   1 
ATOM   5356  C  CA  . SER C 1 110 ? 17.312  6.061   13.197  1.00 25.48  ? 110 SER C CA  1 
ATOM   5357  C  C   . SER C 1 110 ? 16.674  7.233   13.919  1.00 22.69  ? 110 SER C C   1 
ATOM   5358  O  O   . SER C 1 110 ? 16.176  7.055   14.996  1.00 21.81  ? 110 SER C O   1 
ATOM   5359  C  CB  . SER C 1 110 ? 18.410  5.475   14.027  1.00 29.79  ? 110 SER C CB  1 
ATOM   5360  O  OG  . SER C 1 110 ? 19.421  6.444   14.275  1.00 36.07  ? 110 SER C OG  1 
ATOM   5361  N  N   . ARG C 1 111 ? 16.694  8.438   13.368  1.00 21.72  ? 111 ARG C N   1 
ATOM   5362  C  CA  . ARG C 1 111 ? 16.084  9.560   14.044  1.00 23.84  ? 111 ARG C CA  1 
ATOM   5363  C  C   . ARG C 1 111 ? 15.514  10.476  12.976  1.00 20.59  ? 111 ARG C C   1 
ATOM   5364  O  O   . ARG C 1 111 ? 16.151  10.682  11.963  1.00 21.88  ? 111 ARG C O   1 
ATOM   5365  C  CB  . ARG C 1 111 ? 17.171  10.374  14.765  1.00 30.35  ? 111 ARG C CB  1 
ATOM   5366  C  CG  . ARG C 1 111 ? 18.423  9.709   15.326  1.00 36.28  ? 111 ARG C CG  1 
ATOM   5367  C  CD  . ARG C 1 111 ? 19.064  10.491  16.472  1.00 44.23  ? 111 ARG C CD  1 
ATOM   5368  N  NE  . ARG C 1 111 ? 19.559  11.815  16.064  1.00 62.37  ? 111 ARG C NE  1 
ATOM   5369  C  CZ  . ARG C 1 111 ? 20.863  12.214  15.912  1.00 68.24  ? 111 ARG C CZ  1 
ATOM   5370  N  NH1 . ARG C 1 111 ? 21.851  11.329  16.000  1.00 60.44  ? 111 ARG C NH1 1 
ATOM   5371  N  NH2 . ARG C 1 111 ? 21.195  13.496  15.680  1.00 59.71  ? 111 ARG C NH2 1 
ATOM   5372  N  N   . LEU C 1 112 ? 14.381  11.097  13.223  1.00 20.88  ? 112 LEU C N   1 
ATOM   5373  C  CA  . LEU C 1 112 ? 13.796  12.003  12.233  1.00 25.22  ? 112 LEU C CA  1 
ATOM   5374  C  C   . LEU C 1 112 ? 14.621  13.246  11.898  1.00 26.72  ? 112 LEU C C   1 
ATOM   5375  O  O   . LEU C 1 112 ? 14.501  13.744  10.788  1.00 28.21  ? 112 LEU C O   1 
ATOM   5376  C  CB  . LEU C 1 112 ? 12.422  12.472  12.665  1.00 24.41  ? 112 LEU C CB  1 
ATOM   5377  C  CG  . LEU C 1 112 ? 11.594  13.199  11.612  1.00 27.07  ? 112 LEU C CG  1 
ATOM   5378  C  CD1 . LEU C 1 112 ? 11.396  12.385  10.357  1.00 30.08  ? 112 LEU C CD1 1 
ATOM   5379  C  CD2 . LEU C 1 112 ? 10.226  13.490  12.229  1.00 26.34  ? 112 LEU C CD2 1 
ATOM   5380  N  N   . ASP C 1 113 ? 15.398  13.790  12.846  1.00 28.55  ? 113 ASP C N   1 
ATOM   5381  C  CA  . ASP C 1 113 ? 16.049  15.088  12.664  1.00 29.07  ? 113 ASP C CA  1 
ATOM   5382  C  C   . ASP C 1 113 ? 17.118  14.978  11.583  1.00 25.35  ? 113 ASP C C   1 
ATOM   5383  O  O   . ASP C 1 113 ? 17.437  15.933  10.935  1.00 20.57  ? 113 ASP C O   1 
ATOM   5384  C  CB  . ASP C 1 113 ? 16.713  15.576  13.952  1.00 34.47  ? 113 ASP C CB  1 
ATOM   5385  C  CG  . ASP C 1 113 ? 17.706  14.620  14.625  1.00 36.39  ? 113 ASP C CG  1 
ATOM   5386  O  OD1 . ASP C 1 113 ? 17.297  13.497  14.946  1.00 50.33  ? 113 ASP C OD1 1 
ATOM   5387  O  OD2 . ASP C 1 113 ? 18.870  14.993  14.839  1.00 29.54  ? 113 ASP C OD2 1 
ATOM   5388  N  N   . LEU C 1 114 ? 17.745  13.809  11.472  1.00 25.42  ? 114 LEU C N   1 
ATOM   5389  C  CA  . LEU C 1 114 ? 18.754  13.581  10.456  1.00 29.05  ? 114 LEU C CA  1 
ATOM   5390  C  C   . LEU C 1 114 ? 18.080  13.571  9.090   1.00 25.53  ? 114 LEU C C   1 
ATOM   5391  O  O   . LEU C 1 114 ? 18.617  14.142  8.142   1.00 26.18  ? 114 LEU C O   1 
ATOM   5392  C  CB  . LEU C 1 114 ? 19.490  12.257  10.669  1.00 31.95  ? 114 LEU C CB  1 
ATOM   5393  C  CG  . LEU C 1 114 ? 20.439  12.208  11.870  1.00 33.58  ? 114 LEU C CG  1 
ATOM   5394  C  CD1 . LEU C 1 114 ? 20.812  10.768  12.166  1.00 35.38  ? 114 LEU C CD1 1 
ATOM   5395  C  CD2 . LEU C 1 114 ? 21.680  13.029  11.610  1.00 34.74  ? 114 LEU C CD2 1 
ATOM   5396  N  N   . CYS C 1 115 ? 16.932  12.889  9.004   1.00 20.55  ? 115 CYS C N   1 
ATOM   5397  C  CA  . CYS C 1 115 ? 16.152  12.883  7.783   1.00 19.85  ? 115 CYS C CA  1 
ATOM   5398  C  C   . CYS C 1 115 ? 15.793  14.308  7.360   1.00 19.50  ? 115 CYS C C   1 
ATOM   5399  O  O   . CYS C 1 115 ? 16.001  14.714  6.205   1.00 22.31  ? 115 CYS C O   1 
ATOM   5400  C  CB  . CYS C 1 115 ? 14.883  12.068  7.961   1.00 21.27  ? 115 CYS C CB  1 
ATOM   5401  S  SG  . CYS C 1 115 ? 15.191  10.296  8.182   1.00 21.92  ? 115 CYS C SG  1 
ATOM   5402  N  N   . PHE C 1 116 ? 15.294  15.071  8.323   1.00 19.85  ? 116 PHE C N   1 
ATOM   5403  C  CA  . PHE C 1 116 ? 14.894  16.445  8.077   1.00 21.35  ? 116 PHE C CA  1 
ATOM   5404  C  C   . PHE C 1 116 ? 16.080  17.312  7.644   1.00 21.17  ? 116 PHE C C   1 
ATOM   5405  O  O   . PHE C 1 116 ? 15.965  18.154  6.757   1.00 23.84  ? 116 PHE C O   1 
ATOM   5406  C  CB  . PHE C 1 116 ? 14.225  16.958  9.342   1.00 22.03  ? 116 PHE C CB  1 
ATOM   5407  C  CG  . PHE C 1 116 ? 13.519  18.286  9.148   1.00 23.54  ? 116 PHE C CG  1 
ATOM   5408  C  CD1 . PHE C 1 116 ? 14.218  19.489  9.272   1.00 22.98  ? 116 PHE C CD1 1 
ATOM   5409  C  CD2 . PHE C 1 116 ? 12.163  18.319  8.820   1.00 25.50  ? 116 PHE C CD2 1 
ATOM   5410  C  CE1 . PHE C 1 116 ? 13.564  20.694  9.114   1.00 22.56  ? 116 PHE C CE1 1 
ATOM   5411  C  CE2 . PHE C 1 116 ? 11.528  19.547  8.647   1.00 23.90  ? 116 PHE C CE2 1 
ATOM   5412  C  CZ  . PHE C 1 116 ? 12.236  20.720  8.778   1.00 23.06  ? 116 PHE C CZ  1 
ATOM   5413  N  N   . ALA C 1 117 ? 17.219  17.139  8.300   1.00 20.76  ? 117 ALA C N   1 
ATOM   5414  C  CA  . ALA C 1 117 ? 18.401  17.912  7.984   1.00 20.86  ? 117 ALA C CA  1 
ATOM   5415  C  C   . ALA C 1 117 ? 18.813  17.691  6.538   1.00 20.81  ? 117 ALA C C   1 
ATOM   5416  O  O   . ALA C 1 117 ? 19.097  18.639  5.790   1.00 18.82  ? 117 ALA C O   1 
ATOM   5417  C  CB  . ALA C 1 117 ? 19.502  17.474  8.895   1.00 22.72  ? 117 ALA C CB  1 
ATOM   5418  N  N   . LEU C 1 118 ? 18.801  16.420  6.127   1.00 19.57  ? 118 LEU C N   1 
ATOM   5419  C  CA  . LEU C 1 118 ? 19.199  16.114  4.770   1.00 19.07  ? 118 LEU C CA  1 
ATOM   5420  C  C   . LEU C 1 118 ? 18.176  16.670  3.795   1.00 19.40  ? 118 LEU C C   1 
ATOM   5421  O  O   . LEU C 1 118 ? 18.527  17.251  2.771   1.00 21.29  ? 118 LEU C O   1 
ATOM   5422  C  CB  . LEU C 1 118 ? 19.400  14.616  4.574   1.00 18.96  ? 118 LEU C CB  1 
ATOM   5423  C  CG  . LEU C 1 118 ? 19.858  14.209  3.167   1.00 20.27  ? 118 LEU C CG  1 
ATOM   5424  C  CD1 . LEU C 1 118 ? 21.039  14.973  2.643   1.00 19.86  ? 118 LEU C CD1 1 
ATOM   5425  C  CD2 . LEU C 1 118 ? 20.217  12.740  3.151   1.00 22.19  ? 118 LEU C CD2 1 
ATOM   5426  N  N   . ALA C 1 119 ? 16.903  16.493  4.126   1.00 18.68  ? 119 ALA C N   1 
ATOM   5427  C  CA  . ALA C 1 119 ? 15.855  16.977  3.255   1.00 19.03  ? 119 ALA C CA  1 
ATOM   5428  C  C   . ALA C 1 119 ? 15.961  18.488  3.071   1.00 19.56  ? 119 ALA C C   1 
ATOM   5429  O  O   . ALA C 1 119 ? 15.697  19.011  1.992   1.00 19.22  ? 119 ALA C O   1 
ATOM   5430  C  CB  . ALA C 1 119 ? 14.523  16.580  3.845   1.00 20.09  ? 119 ALA C CB  1 
ATOM   5431  N  N   . THR C 1 120 ? 16.297  19.191  4.146   1.00 20.11  ? 120 THR C N   1 
ATOM   5432  C  CA  . THR C 1 120 ? 16.442  20.633  4.104   1.00 21.07  ? 120 THR C CA  1 
ATOM   5433  C  C   . THR C 1 120 ? 17.544  20.983  3.123   1.00 23.98  ? 120 THR C C   1 
ATOM   5434  O  O   . THR C 1 120 ? 17.370  21.888  2.317   1.00 25.70  ? 120 THR C O   1 
ATOM   5435  C  CB  . THR C 1 120 ? 16.774  21.187  5.490   1.00 22.69  ? 120 THR C CB  1 
ATOM   5436  O  OG1 . THR C 1 120 ? 15.660  20.859  6.300   1.00 23.60  ? 120 THR C OG1 1 
ATOM   5437  C  CG2 . THR C 1 120 ? 16.930  22.698  5.483   1.00 23.56  ? 120 THR C CG2 1 
ATOM   5438  N  N   . GLU C 1 121 ? 18.687  20.289  3.204   1.00 26.03  ? 121 GLU C N   1 
ATOM   5439  C  CA  . GLU C 1 121 ? 19.825  20.631  2.352   1.00 26.31  ? 121 GLU C CA  1 
ATOM   5440  C  C   . GLU C 1 121 ? 19.495  20.380  0.883   1.00 22.63  ? 121 GLU C C   1 
ATOM   5441  O  O   . GLU C 1 121 ? 19.824  21.200  0.020   1.00 22.56  ? 121 GLU C O   1 
ATOM   5442  C  CB  . GLU C 1 121 ? 21.139  19.913  2.683   1.00 30.76  ? 121 GLU C CB  1 
ATOM   5443  C  CG  . GLU C 1 121 ? 21.798  20.378  3.975   1.00 32.93  ? 121 GLU C CG  1 
ATOM   5444  C  CD  . GLU C 1 121 ? 22.490  21.726  4.003   1.00 36.79  ? 121 GLU C CD  1 
ATOM   5445  O  OE1 . GLU C 1 121 ? 22.831  22.204  2.919   1.00 35.95  ? 121 GLU C OE1 1 
ATOM   5446  O  OE2 . GLU C 1 121 ? 22.704  22.274  5.120   1.00 48.95  ? 121 GLU C OE2 1 
ATOM   5447  N  N   . ILE C 1 122 ? 18.891  19.223  0.587   1.00 22.53  ? 122 ILE C N   1 
ATOM   5448  C  CA  . ILE C 1 122 ? 18.489  18.881  -0.782  1.00 22.07  ? 122 ILE C CA  1 
ATOM   5449  C  C   . ILE C 1 122 ? 17.539  19.945  -1.343  1.00 22.93  ? 122 ILE C C   1 
ATOM   5450  O  O   . ILE C 1 122 ? 17.795  20.532  -2.380  1.00 23.97  ? 122 ILE C O   1 
ATOM   5451  C  CB  . ILE C 1 122 ? 17.885  17.464  -0.819  1.00 21.09  ? 122 ILE C CB  1 
ATOM   5452  C  CG1 . ILE C 1 122 ? 18.962  16.449  -0.562  1.00 21.56  ? 122 ILE C CG1 1 
ATOM   5453  C  CG2 . ILE C 1 122 ? 17.192  17.185  -2.134  1.00 21.11  ? 122 ILE C CG2 1 
ATOM   5454  C  CD1 . ILE C 1 122 ? 18.447  15.052  -0.302  1.00 21.81  ? 122 ILE C CD1 1 
ATOM   5455  N  N   . MET C 1 123 ? 16.460  20.243  -0.638  1.00 25.71  ? 123 MET C N   1 
ATOM   5456  C  CA  . MET C 1 123 ? 15.467  21.180  -1.133  1.00 26.80  ? 123 MET C CA  1 
ATOM   5457  C  C   . MET C 1 123 ? 15.995  22.604  -1.214  1.00 26.61  ? 123 MET C C   1 
ATOM   5458  O  O   . MET C 1 123 ? 15.560  23.380  -2.072  1.00 32.09  ? 123 MET C O   1 
ATOM   5459  C  CB  . MET C 1 123 ? 14.219  21.158  -0.259  1.00 29.36  ? 123 MET C CB  1 
ATOM   5460  C  CG  . MET C 1 123 ? 13.434  19.894  -0.518  1.00 38.12  ? 123 MET C CG  1 
ATOM   5461  S  SD  . MET C 1 123 ? 12.653  19.815  -2.138  1.00 39.61  ? 123 MET C SD  1 
ATOM   5462  C  CE  . MET C 1 123 ? 12.007  21.508  -2.137  1.00 35.87  ? 123 MET C CE  1 
ATOM   5463  N  N   . GLY C 1 124 ? 16.906  22.940  -0.313  1.00 25.21  ? 124 GLY C N   1 
ATOM   5464  C  CA  . GLY C 1 124 ? 17.566  24.225  -0.378  1.00 23.04  ? 124 GLY C CA  1 
ATOM   5465  C  C   . GLY C 1 124 ? 18.259  24.393  -1.725  1.00 23.03  ? 124 GLY C C   1 
ATOM   5466  O  O   . GLY C 1 124 ? 18.186  25.447  -2.283  1.00 24.66  ? 124 GLY C O   1 
ATOM   5467  N  N   . ARG C 1 125 ? 18.910  23.360  -2.270  1.00 24.82  ? 125 ARG C N   1 
ATOM   5468  C  CA  . ARG C 1 125 ? 19.596  23.473  -3.551  1.00 24.39  ? 125 ARG C CA  1 
ATOM   5469  C  C   . ARG C 1 125 ? 18.605  23.486  -4.708  1.00 25.55  ? 125 ARG C C   1 
ATOM   5470  O  O   . ARG C 1 125 ? 18.912  23.957  -5.795  1.00 25.85  ? 125 ARG C O   1 
ATOM   5471  C  CB  . ARG C 1 125 ? 20.529  22.294  -3.795  1.00 26.21  ? 125 ARG C CB  1 
ATOM   5472  C  CG  . ARG C 1 125 ? 21.608  22.154  -2.732  1.00 33.85  ? 125 ARG C CG  1 
ATOM   5473  C  CD  . ARG C 1 125 ? 22.858  22.934  -2.960  1.00 41.58  ? 125 ARG C CD  1 
ATOM   5474  N  NE  . ARG C 1 125 ? 23.349  22.565  -4.294  1.00 57.47  ? 125 ARG C NE  1 
ATOM   5475  C  CZ  . ARG C 1 125 ? 24.225  21.592  -4.584  1.00 57.35  ? 125 ARG C CZ  1 
ATOM   5476  N  NH1 . ARG C 1 125 ? 24.970  21.087  -3.600  1.00 59.41  ? 125 ARG C NH1 1 
ATOM   5477  N  NH2 . ARG C 1 125 ? 24.349  21.185  -5.850  1.00 51.81  ? 125 ARG C NH2 1 
ATOM   5478  N  N   . LEU C 1 126 ? 17.417  22.928  -4.494  1.00 24.21  ? 126 LEU C N   1 
ATOM   5479  C  CA  . LEU C 1 126 ? 16.510  22.708  -5.587  1.00 23.42  ? 126 LEU C CA  1 
ATOM   5480  C  C   . LEU C 1 126 ? 15.420  23.760  -5.625  1.00 25.83  ? 126 LEU C C   1 
ATOM   5481  O  O   . LEU C 1 126 ? 14.592  23.674  -6.524  1.00 25.05  ? 126 LEU C O   1 
ATOM   5482  C  CB  . LEU C 1 126 ? 15.861  21.335  -5.466  1.00 23.51  ? 126 LEU C CB  1 
ATOM   5483  C  CG  . LEU C 1 126 ? 16.763  20.121  -5.689  1.00 24.23  ? 126 LEU C CG  1 
ATOM   5484  C  CD1 . LEU C 1 126 ? 15.903  18.831  -5.583  1.00 26.32  ? 126 LEU C CD1 1 
ATOM   5485  C  CD2 . LEU C 1 126 ? 17.481  20.210  -7.021  1.00 24.79  ? 126 LEU C CD2 1 
ATOM   5486  N  N   . ARG C 1 127 ? 15.317  24.681  -4.658  1.00 32.08  ? 127 ARG C N   1 
ATOM   5487  C  CA  . ARG C 1 127 ? 14.186  25.613  -4.713  1.00 38.03  ? 127 ARG C CA  1 
ATOM   5488  C  C   . ARG C 1 127 ? 14.356  26.484  -5.967  1.00 35.77  ? 127 ARG C C   1 
ATOM   5489  O  O   . ARG C 1 127 ? 15.435  26.687  -6.503  1.00 36.30  ? 127 ARG C O   1 
ATOM   5490  C  CB  . ARG C 1 127 ? 13.907  26.404  -3.435  1.00 39.46  ? 127 ARG C CB  1 
ATOM   5491  C  CG  . ARG C 1 127 ? 14.957  27.449  -3.117  1.00 41.30  ? 127 ARG C CG  1 
ATOM   5492  C  CD  . ARG C 1 127 ? 14.847  27.335  -1.621  1.00 46.87  ? 127 ARG C CD  1 
ATOM   5493  N  NE  . ARG C 1 127 ? 15.647  28.343  -0.938  1.00 45.15  ? 127 ARG C NE  1 
ATOM   5494  C  CZ  . ARG C 1 127 ? 15.066  29.159  -0.104  1.00 48.80  ? 127 ARG C CZ  1 
ATOM   5495  N  NH1 . ARG C 1 127 ? 13.752  29.403  -0.159  1.00 57.00  ? 127 ARG C NH1 1 
ATOM   5496  N  NH2 . ARG C 1 127 ? 15.829  29.754  0.771   1.00 48.84  ? 127 ARG C NH2 1 
ATOM   5497  N  N   . GLY C 1 128 ? 13.269  26.869  -6.582  1.00 31.84  ? 128 GLY C N   1 
ATOM   5498  C  CA  . GLY C 1 128 ? 13.442  27.480  -7.875  1.00 28.21  ? 128 GLY C CA  1 
ATOM   5499  C  C   . GLY C 1 128 ? 13.299  26.442  -8.982  1.00 27.71  ? 128 GLY C C   1 
ATOM   5500  O  O   . GLY C 1 128 ? 12.829  26.782  -10.055 1.00 32.94  ? 128 GLY C O   1 
ATOM   5501  N  N   . ALA C 1 129 ? 13.663  25.186  -8.765  1.00 21.62  ? 129 ALA C N   1 
ATOM   5502  C  CA  . ALA C 1 129 ? 13.718  24.280  -9.892  1.00 22.98  ? 129 ALA C CA  1 
ATOM   5503  C  C   . ALA C 1 129 ? 12.715  23.149  -9.789  1.00 24.43  ? 129 ALA C C   1 
ATOM   5504  O  O   . ALA C 1 129 ? 12.523  22.437  -10.767 1.00 25.54  ? 129 ALA C O   1 
ATOM   5505  C  CB  . ALA C 1 129 ? 15.096  23.732  -10.074 1.00 24.55  ? 129 ALA C CB  1 
ATOM   5506  N  N   . VAL C 1 130 ? 12.057  22.987  -8.648  1.00 25.03  ? 130 VAL C N   1 
ATOM   5507  C  CA  . VAL C 1 130 ? 11.160  21.854  -8.499  1.00 24.23  ? 130 VAL C CA  1 
ATOM   5508  C  C   . VAL C 1 130 ? 9.958   22.351  -7.743  1.00 22.52  ? 130 VAL C C   1 
ATOM   5509  O  O   . VAL C 1 130 ? 10.013  23.407  -7.146  1.00 22.37  ? 130 VAL C O   1 
ATOM   5510  C  CB  . VAL C 1 130 ? 11.764  20.642  -7.769  1.00 24.51  ? 130 VAL C CB  1 
ATOM   5511  C  CG1 . VAL C 1 130 ? 12.942  20.061  -8.519  1.00 27.25  ? 130 VAL C CG1 1 
ATOM   5512  C  CG2 . VAL C 1 130 ? 12.177  20.968  -6.343  1.00 25.90  ? 130 VAL C CG2 1 
ATOM   5513  N  N   . THR C 1 131 ? 8.920   21.534  -7.754  1.00 24.97  ? 131 THR C N   1 
ATOM   5514  C  CA  . THR C 1 131 ? 7.670   21.794  -7.058  1.00 27.51  ? 131 THR C CA  1 
ATOM   5515  C  C   . THR C 1 131 ? 7.354   20.547  -6.230  1.00 27.02  ? 131 THR C C   1 
ATOM   5516  O  O   . THR C 1 131 ? 7.240   19.431  -6.770  1.00 29.27  ? 131 THR C O   1 
ATOM   5517  C  CB  . THR C 1 131 ? 6.551   22.114  -8.066  1.00 28.36  ? 131 THR C CB  1 
ATOM   5518  O  OG1 . THR C 1 131 ? 6.815   23.358  -8.728  1.00 29.22  ? 131 THR C OG1 1 
ATOM   5519  C  CG2 . THR C 1 131 ? 5.189   22.218  -7.403  1.00 27.18  ? 131 THR C CG2 1 
ATOM   5520  N  N   . PRO C 1 132 ? 7.200   20.682  -4.901  1.00 25.18  ? 132 PRO C N   1 
ATOM   5521  C  CA  . PRO C 1 132 ? 6.951   19.511  -4.068  1.00 25.17  ? 132 PRO C CA  1 
ATOM   5522  C  C   . PRO C 1 132 ? 5.587   18.963  -4.410  1.00 24.25  ? 132 PRO C C   1 
ATOM   5523  O  O   . PRO C 1 132 ? 4.709   19.722  -4.676  1.00 24.46  ? 132 PRO C O   1 
ATOM   5524  C  CB  . PRO C 1 132 ? 7.027   20.074  -2.664  1.00 27.91  ? 132 PRO C CB  1 
ATOM   5525  C  CG  . PRO C 1 132 ? 6.764   21.547  -2.807  1.00 27.52  ? 132 PRO C CG  1 
ATOM   5526  C  CD  . PRO C 1 132 ? 7.248   21.950  -4.155  1.00 27.02  ? 132 PRO C CD  1 
ATOM   5527  N  N   . GLN C 1 133 ? 5.423   17.661  -4.468  1.00 24.10  ? 133 GLN C N   1 
ATOM   5528  C  CA  . GLN C 1 133 ? 4.127   17.058  -4.727  1.00 23.62  ? 133 GLN C CA  1 
ATOM   5529  C  C   . GLN C 1 133 ? 3.655   16.313  -3.496  1.00 24.64  ? 133 GLN C C   1 
ATOM   5530  O  O   . GLN C 1 133 ? 2.481   16.348  -3.207  1.00 28.95  ? 133 GLN C O   1 
ATOM   5531  C  CB  . GLN C 1 133 ? 4.110   15.939  -5.767  1.00 25.10  ? 133 GLN C CB  1 
ATOM   5532  C  CG  . GLN C 1 133 ? 4.499   16.419  -7.151  1.00 30.27  ? 133 GLN C CG  1 
ATOM   5533  C  CD  . GLN C 1 133 ? 3.495   17.432  -7.632  1.00 36.44  ? 133 GLN C CD  1 
ATOM   5534  O  OE1 . GLN C 1 133 ? 2.309   17.117  -7.665  1.00 39.02  ? 133 GLN C OE1 1 
ATOM   5535  N  NE2 . GLN C 1 133 ? 3.937   18.644  -7.942  1.00 35.72  ? 133 GLN C NE2 1 
ATOM   5536  N  N   . ASP C 1 134 ? 4.553   15.626  -2.805  1.00 23.29  ? 134 ASP C N   1 
ATOM   5537  C  CA  . ASP C 1 134 ? 4.203   14.921  -1.588  1.00 24.12  ? 134 ASP C CA  1 
ATOM   5538  C  C   . ASP C 1 134 ? 5.394   14.958  -0.627  1.00 25.70  ? 134 ASP C C   1 
ATOM   5539  O  O   . ASP C 1 134 ? 6.549   14.883  -1.029  1.00 27.10  ? 134 ASP C O   1 
ATOM   5540  C  CB  . ASP C 1 134 ? 3.830   13.505  -1.953  1.00 25.83  ? 134 ASP C CB  1 
ATOM   5541  C  CG  . ASP C 1 134 ? 2.978   12.743  -0.951  1.00 29.35  ? 134 ASP C CG  1 
ATOM   5542  O  OD1 . ASP C 1 134 ? 2.351   13.422  -0.148  1.00 29.93  ? 134 ASP C OD1 1 
ATOM   5543  O  OD2 . ASP C 1 134 ? 2.945   11.485  -1.015  1.00 28.19  ? 134 ASP C OD2 1 
ATOM   5544  N  N   . GLU C 1 135 ? 5.106   15.092  0.660   1.00 25.08  ? 135 GLU C N   1 
ATOM   5545  C  CA  . GLU C 1 135 ? 6.113   15.018  1.705   1.00 21.60  ? 135 GLU C CA  1 
ATOM   5546  C  C   . GLU C 1 135 ? 5.507   14.252  2.876   1.00 22.14  ? 135 GLU C C   1 
ATOM   5547  O  O   . GLU C 1 135 ? 4.478   14.632  3.356   1.00 24.86  ? 135 GLU C O   1 
ATOM   5548  C  CB  . GLU C 1 135 ? 6.465   16.409  2.171   1.00 20.42  ? 135 GLU C CB  1 
ATOM   5549  C  CG  . GLU C 1 135 ? 7.459   16.397  3.307   1.00 21.69  ? 135 GLU C CG  1 
ATOM   5550  C  CD  . GLU C 1 135 ? 7.820   17.793  3.753   1.00 24.95  ? 135 GLU C CD  1 
ATOM   5551  O  OE1 . GLU C 1 135 ? 7.371   18.717  3.012   1.00 30.69  ? 135 GLU C OE1 1 
ATOM   5552  O  OE2 . GLU C 1 135 ? 8.478   17.954  4.826   1.00 24.69  ? 135 GLU C OE2 1 
ATOM   5553  N  N   . VAL C 1 136 ? 6.083   13.125  3.268   1.00 21.78  ? 136 VAL C N   1 
ATOM   5554  C  CA  . VAL C 1 136 ? 5.559   12.334  4.353   1.00 20.42  ? 136 VAL C CA  1 
ATOM   5555  C  C   . VAL C 1 136 ? 6.677   12.040  5.332   1.00 18.87  ? 136 VAL C C   1 
ATOM   5556  O  O   . VAL C 1 136 ? 7.768   11.702  4.919   1.00 17.27  ? 136 VAL C O   1 
ATOM   5557  C  CB  . VAL C 1 136 ? 4.946   11.057  3.777   1.00 24.02  ? 136 VAL C CB  1 
ATOM   5558  C  CG1 . VAL C 1 136 ? 4.603   10.050  4.868   1.00 27.91  ? 136 VAL C CG1 1 
ATOM   5559  C  CG2 . VAL C 1 136 ? 3.723   11.407  2.942   1.00 24.39  ? 136 VAL C CG2 1 
ATOM   5560  N  N   . HIS C 1 137 ? 6.387   12.258  6.613   1.00 19.52  ? 137 HIS C N   1 
ATOM   5561  C  CA  . HIS C 1 137 ? 7.270   11.969  7.723   1.00 18.65  ? 137 HIS C CA  1 
ATOM   5562  C  C   . HIS C 1 137 ? 6.749   10.702  8.358   1.00 18.80  ? 137 HIS C C   1 
ATOM   5563  O  O   . HIS C 1 137 ? 5.640   10.664  8.864   1.00 21.24  ? 137 HIS C O   1 
ATOM   5564  C  CB  . HIS C 1 137 ? 7.255   13.140  8.711   1.00 18.95  ? 137 HIS C CB  1 
ATOM   5565  C  CG  . HIS C 1 137 ? 7.747   14.436  8.106   1.00 18.88  ? 137 HIS C CG  1 
ATOM   5566  N  ND1 . HIS C 1 137 ? 7.973   15.548  8.875   1.00 20.45  ? 137 HIS C ND1 1 
ATOM   5567  C  CD2 . HIS C 1 137 ? 8.112   14.786  6.859   1.00 19.37  ? 137 HIS C CD2 1 
ATOM   5568  C  CE1 . HIS C 1 137 ? 8.425   16.530  8.104   1.00 22.35  ? 137 HIS C CE1 1 
ATOM   5569  N  NE2 . HIS C 1 137 ? 8.514   16.095  6.871   1.00 19.86  ? 137 HIS C NE2 1 
ATOM   5570  N  N   . GLY C 1 138 ? 7.495   9.623   8.228   1.00 20.59  ? 138 GLY C N   1 
ATOM   5571  C  CA  . GLY C 1 138 ? 7.025   8.324   8.684   1.00 20.71  ? 138 GLY C CA  1 
ATOM   5572  C  C   . GLY C 1 138 ? 7.764   7.914   9.934   1.00 19.09  ? 138 GLY C C   1 
ATOM   5573  O  O   . GLY C 1 138 ? 8.900   8.351   10.129  1.00 21.21  ? 138 GLY C O   1 
ATOM   5574  N  N   . PHE C 1 139 ? 7.120   7.058   10.729  1.00 19.88  ? 139 PHE C N   1 
ATOM   5575  C  CA  . PHE C 1 139 ? 7.691   6.593   11.978  1.00 21.58  ? 139 PHE C CA  1 
ATOM   5576  C  C   . PHE C 1 139 ? 7.349   5.137   12.185  1.00 21.35  ? 139 PHE C C   1 
ATOM   5577  O  O   . PHE C 1 139 ? 6.276   4.734   11.835  1.00 23.51  ? 139 PHE C O   1 
ATOM   5578  C  CB  . PHE C 1 139 ? 7.199   7.470   13.136  1.00 22.77  ? 139 PHE C CB  1 
ATOM   5579  C  CG  . PHE C 1 139 ? 5.694   7.602   13.213  1.00 24.45  ? 139 PHE C CG  1 
ATOM   5580  C  CD1 . PHE C 1 139 ? 4.933   6.662   13.906  1.00 25.56  ? 139 PHE C CD1 1 
ATOM   5581  C  CD2 . PHE C 1 139 ? 5.047   8.661   12.606  1.00 24.27  ? 139 PHE C CD2 1 
ATOM   5582  C  CE1 . PHE C 1 139 ? 3.549   6.752   13.936  1.00 24.68  ? 139 PHE C CE1 1 
ATOM   5583  C  CE2 . PHE C 1 139 ? 3.657   8.765   12.686  1.00 26.63  ? 139 PHE C CE2 1 
ATOM   5584  C  CZ  . PHE C 1 139 ? 2.906   7.801   13.332  1.00 22.81  ? 139 PHE C CZ  1 
ATOM   5585  N  N   . LYS C 1 140 ? 8.257   4.384   12.791  1.00 26.64  ? 140 LYS C N   1 
ATOM   5586  C  CA  . LYS C 1 140 ? 7.987   3.020   13.235  1.00 34.15  ? 140 LYS C CA  1 
ATOM   5587  C  C   . LYS C 1 140 ? 7.035   3.043   14.424  1.00 29.30  ? 140 LYS C C   1 
ATOM   5588  O  O   . LYS C 1 140 ? 7.074   3.933   15.291  1.00 26.78  ? 140 LYS C O   1 
ATOM   5589  C  CB  . LYS C 1 140 ? 9.272   2.223   13.532  1.00 48.67  ? 140 LYS C CB  1 
ATOM   5590  C  CG  . LYS C 1 140 ? 9.537   1.627   14.956  1.00 77.18  ? 140 LYS C CG  1 
ATOM   5591  C  CD  . LYS C 1 140 ? 9.760   2.713   16.034  1.00 100.39 ? 140 LYS C CD  1 
ATOM   5592  C  CE  . LYS C 1 140 ? 10.262  2.340   17.409  1.00 93.35  ? 140 LYS C CE  1 
ATOM   5593  N  NZ  . LYS C 1 140 ? 11.481  1.545   17.272  1.00 108.61 ? 140 LYS C NZ  1 
ATOM   5594  N  N   . TYR C 1 141 ? 6.178   2.033   14.407  1.00 31.30  ? 141 TYR C N   1 
ATOM   5595  C  CA  . TYR C 1 141 ? 5.090   1.889   15.357  1.00 45.98  ? 141 TYR C CA  1 
ATOM   5596  C  C   . TYR C 1 141 ? 5.277   0.582   16.127  1.00 51.94  ? 141 TYR C C   1 
ATOM   5597  O  O   . TYR C 1 141 ? 5.019   -0.519  15.628  1.00 54.48  ? 141 TYR C O   1 
ATOM   5598  C  CB  . TYR C 1 141 ? 3.830   1.963   14.494  1.00 47.65  ? 141 TYR C CB  1 
ATOM   5599  C  CG  . TYR C 1 141 ? 2.569   2.391   15.193  1.00 50.09  ? 141 TYR C CG  1 
ATOM   5600  C  CD1 . TYR C 1 141 ? 2.440   3.702   15.577  1.00 59.05  ? 141 TYR C CD1 1 
ATOM   5601  C  CD2 . TYR C 1 141 ? 1.499   1.530   15.371  1.00 61.13  ? 141 TYR C CD2 1 
ATOM   5602  C  CE1 . TYR C 1 141 ? 1.280   4.165   16.151  1.00 66.08  ? 141 TYR C CE1 1 
ATOM   5603  C  CE2 . TYR C 1 141 ? 0.337   1.969   15.972  1.00 68.23  ? 141 TYR C CE2 1 
ATOM   5604  C  CZ  . TYR C 1 141 ? 0.236   3.294   16.365  1.00 72.78  ? 141 TYR C CZ  1 
ATOM   5605  O  OH  . TYR C 1 141 ? -0.860  3.820   16.982  1.00 93.30  ? 141 TYR C OH  1 
ATOM   5606  N  N   . PHE C 1 142 ? 5.746   0.726   17.364  1.00 61.88  ? 142 PHE C N   1 
ATOM   5607  C  CA  . PHE C 1 142 ? 5.795   -0.385  18.299  1.00 62.17  ? 142 PHE C CA  1 
ATOM   5608  C  C   . PHE C 1 142 ? 6.805   -1.373  17.749  1.00 39.32  ? 142 PHE C C   1 
ATOM   5609  O  O   . PHE C 1 142 ? 7.898   -0.979  17.420  1.00 37.43  ? 142 PHE C O   1 
ATOM   5610  C  CB  . PHE C 1 142 ? 4.402   -0.948  18.638  1.00 67.39  ? 142 PHE C CB  1 
ATOM   5611  C  CG  . PHE C 1 142 ? 3.653   -0.027  19.595  1.00 78.47  ? 142 PHE C CG  1 
ATOM   5612  C  CD1 . PHE C 1 142 ? 4.056   0.088   20.937  1.00 79.48  ? 142 PHE C CD1 1 
ATOM   5613  C  CD2 . PHE C 1 142 ? 2.591   0.752   19.136  1.00 70.46  ? 142 PHE C CD2 1 
ATOM   5614  C  CE1 . PHE C 1 142 ? 3.394   0.945   21.799  1.00 74.01  ? 142 PHE C CE1 1 
ATOM   5615  C  CE2 . PHE C 1 142 ? 1.916   1.594   20.006  1.00 69.19  ? 142 PHE C CE2 1 
ATOM   5616  C  CZ  . PHE C 1 142 ? 2.320   1.686   21.331  1.00 73.57  ? 142 PHE C CZ  1 
ATOM   5617  N  N   . ASP C 1 143 ? 6.368   -2.596  17.549  1.00 31.88  ? 143 ASP C N   1 
ATOM   5618  C  CA  . ASP C 1 143 ? 7.261   -3.684  17.232  1.00 32.94  ? 143 ASP C CA  1 
ATOM   5619  C  C   . ASP C 1 143 ? 7.064   -4.048  15.770  1.00 27.79  ? 143 ASP C C   1 
ATOM   5620  O  O   . ASP C 1 143 ? 6.507   -5.090  15.408  1.00 25.45  ? 143 ASP C O   1 
ATOM   5621  C  CB  . ASP C 1 143 ? 7.003   -4.817  18.199  1.00 39.88  ? 143 ASP C CB  1 
ATOM   5622  C  CG  . ASP C 1 143 ? 5.543   -5.209  18.316  1.00 45.06  ? 143 ASP C CG  1 
ATOM   5623  O  OD1 . ASP C 1 143 ? 4.694   -4.257  18.432  1.00 46.91  ? 143 ASP C OD1 1 
ATOM   5624  O  OD2 . ASP C 1 143 ? 5.295   -6.453  18.304  1.00 46.05  ? 143 ASP C OD2 1 
ATOM   5625  N  N   . GLU C 1 144 ? 7.484   -3.094  14.945  1.00 25.56  ? 144 GLU C N   1 
ATOM   5626  C  CA  . GLU C 1 144 ? 7.451   -3.202  13.500  1.00 28.10  ? 144 GLU C CA  1 
ATOM   5627  C  C   . GLU C 1 144 ? 6.014   -3.303  12.980  1.00 29.14  ? 144 GLU C C   1 
ATOM   5628  O  O   . GLU C 1 144 ? 5.815   -3.864  11.900  1.00 28.47  ? 144 GLU C O   1 
ATOM   5629  C  CB  . GLU C 1 144 ? 8.370   -4.353  13.083  1.00 30.14  ? 144 GLU C CB  1 
ATOM   5630  C  CG  . GLU C 1 144 ? 9.849   -4.060  13.340  1.00 34.27  ? 144 GLU C CG  1 
ATOM   5631  C  CD  . GLU C 1 144 ? 10.400  -2.847  12.599  1.00 37.67  ? 144 GLU C CD  1 
ATOM   5632  O  OE1 . GLU C 1 144 ? 9.837   -2.500  11.520  1.00 36.03  ? 144 GLU C OE1 1 
ATOM   5633  O  OE2 . GLU C 1 144 ? 11.373  -2.245  13.122  1.00 42.29  ? 144 GLU C OE2 1 
ATOM   5634  N  N   . ARG C 1 145 ? 5.048   -2.701  13.712  1.00 27.29  ? 145 ARG C N   1 
ATOM   5635  C  CA  . ARG C 1 145 ? 3.629   -2.764  13.375  1.00 26.01  ? 145 ARG C CA  1 
ATOM   5636  C  C   . ARG C 1 145 ? 3.263   -1.597  12.484  1.00 25.43  ? 145 ARG C C   1 
ATOM   5637  O  O   . ARG C 1 145 ? 3.988   -0.626  12.405  1.00 28.33  ? 145 ARG C O   1 
ATOM   5638  C  CB  . ARG C 1 145 ? 2.749   -2.850  14.615  1.00 26.54  ? 145 ARG C CB  1 
ATOM   5639  C  CG  . ARG C 1 145 ? 3.047   -4.159  15.342  1.00 29.36  ? 145 ARG C CG  1 
ATOM   5640  C  CD  . ARG C 1 145 ? 1.910   -4.541  16.246  1.00 30.09  ? 145 ARG C CD  1 
ATOM   5641  N  NE  . ARG C 1 145 ? 2.324   -5.760  16.932  1.00 30.43  ? 145 ARG C NE  1 
ATOM   5642  C  CZ  . ARG C 1 145 ? 1.897   -7.009  16.733  1.00 32.65  ? 145 ARG C CZ  1 
ATOM   5643  N  NH1 . ARG C 1 145 ? 0.852   -7.295  15.962  1.00 31.05  ? 145 ARG C NH1 1 
ATOM   5644  N  NH2 . ARG C 1 145 ? 2.527   -7.987  17.365  1.00 27.55  ? 145 ARG C NH2 1 
ATOM   5645  N  N   . ASP C 1 146 ? 2.223   -1.791  11.677  1.00 27.99  ? 146 ASP C N   1 
ATOM   5646  C  CA  . ASP C 1 146 ? 1.671   -0.720  10.854  1.00 27.51  ? 146 ASP C CA  1 
ATOM   5647  C  C   . ASP C 1 146 ? 0.383   -0.257  11.524  1.00 26.46  ? 146 ASP C C   1 
ATOM   5648  O  O   . ASP C 1 146 ? 0.055   -0.698  12.630  1.00 23.48  ? 146 ASP C O   1 
ATOM   5649  C  CB  . ASP C 1 146 ? 1.540   -1.148  9.398   1.00 26.61  ? 146 ASP C CB  1 
ATOM   5650  C  CG  . ASP C 1 146 ? 0.642   -2.350  9.193   1.00 27.46  ? 146 ASP C CG  1 
ATOM   5651  O  OD1 . ASP C 1 146 ? -0.255  -2.518  10.030  1.00 27.47  ? 146 ASP C OD1 1 
ATOM   5652  O  OD2 . ASP C 1 146 ? 0.867   -3.135  8.244   1.00 27.77  ? 146 ASP C OD2 1 
ATOM   5653  N  N   . MET C 1 147 ? -0.333  0.628   10.838  1.00 26.55  ? 147 MET C N   1 
ATOM   5654  C  CA  . MET C 1 147 ? -1.502  1.262   11.430  1.00 28.95  ? 147 MET C CA  1 
ATOM   5655  C  C   . MET C 1 147 ? -2.633  0.249   11.622  1.00 26.64  ? 147 MET C C   1 
ATOM   5656  O  O   . MET C 1 147 ? -3.536  0.463   12.418  1.00 27.13  ? 147 MET C O   1 
ATOM   5657  C  CB  . MET C 1 147 ? -2.062  2.388   10.541  1.00 32.69  ? 147 MET C CB  1 
ATOM   5658  C  CG  . MET C 1 147 ? -1.267  3.647   10.565  1.00 34.93  ? 147 MET C CG  1 
ATOM   5659  S  SD  . MET C 1 147 ? -1.505  4.415   12.165  1.00 33.85  ? 147 MET C SD  1 
ATOM   5660  C  CE  . MET C 1 147 ? -0.272  5.715   12.105  1.00 40.83  ? 147 MET C CE  1 
ATOM   5661  N  N   . LEU C 1 148 ? -2.635  -0.858  10.883  1.00 23.22  ? 148 LEU C N   1 
ATOM   5662  C  CA  . LEU C 1 148 ? -3.703  -1.833  11.052  1.00 21.66  ? 148 LEU C CA  1 
ATOM   5663  C  C   . LEU C 1 148 ? -3.378  -2.778  12.202  1.00 23.42  ? 148 LEU C C   1 
ATOM   5664  O  O   . LEU C 1 148 ? -4.167  -3.658  12.492  1.00 25.08  ? 148 LEU C O   1 
ATOM   5665  C  CB  . LEU C 1 148 ? -3.882  -2.629  9.765   1.00 24.93  ? 148 LEU C CB  1 
ATOM   5666  C  CG  . LEU C 1 148 ? -4.228  -1.831  8.505   1.00 28.13  ? 148 LEU C CG  1 
ATOM   5667  C  CD1 . LEU C 1 148 ? -4.306  -2.833  7.347   1.00 30.95  ? 148 LEU C CD1 1 
ATOM   5668  C  CD2 . LEU C 1 148 ? -5.525  -1.029  8.611   1.00 28.44  ? 148 LEU C CD2 1 
ATOM   5669  N  N   . GLY C 1 149 ? -2.199  -2.646  12.826  1.00 22.86  ? 149 GLY C N   1 
ATOM   5670  C  CA  . GLY C 1 149 ? -1.867  -3.364  14.046  1.00 20.70  ? 149 GLY C CA  1 
ATOM   5671  C  C   . GLY C 1 149 ? -1.193  -4.705  13.794  1.00 22.08  ? 149 GLY C C   1 
ATOM   5672  O  O   . GLY C 1 149 ? -1.009  -5.482  14.731  1.00 20.73  ? 149 GLY C O   1 
ATOM   5673  N  N   . PHE C 1 150 ? -0.763  -4.932  12.548  1.00 24.96  ? 150 PHE C N   1 
ATOM   5674  C  CA  . PHE C 1 150 ? -0.048  -6.133  12.151  1.00 27.21  ? 150 PHE C CA  1 
ATOM   5675  C  C   . PHE C 1 150 ? 1.426   -5.823  11.932  1.00 28.41  ? 150 PHE C C   1 
ATOM   5676  O  O   . PHE C 1 150 ? 1.781   -4.734  11.476  1.00 26.63  ? 150 PHE C O   1 
ATOM   5677  C  CB  . PHE C 1 150 ? -0.626  -6.641  10.827  1.00 28.57  ? 150 PHE C CB  1 
ATOM   5678  C  CG  . PHE C 1 150 ? -1.925  -7.391  11.063  1.00 24.65  ? 150 PHE C CG  1 
ATOM   5679  C  CD1 . PHE C 1 150 ? -3.074  -6.735  11.431  1.00 22.80  ? 150 PHE C CD1 1 
ATOM   5680  C  CD2 . PHE C 1 150 ? -1.947  -8.762  10.996  1.00 26.57  ? 150 PHE C CD2 1 
ATOM   5681  C  CE1 . PHE C 1 150 ? -4.228  -7.440  11.681  1.00 25.58  ? 150 PHE C CE1 1 
ATOM   5682  C  CE2 . PHE C 1 150 ? -3.105  -9.463  11.263  1.00 25.55  ? 150 PHE C CE2 1 
ATOM   5683  C  CZ  . PHE C 1 150 ? -4.242  -8.799  11.594  1.00 26.05  ? 150 PHE C CZ  1 
ATOM   5684  N  N   . VAL C 1 151 ? 2.260   -6.825  12.206  1.00 29.56  ? 151 VAL C N   1 
ATOM   5685  C  CA  . VAL C 1 151 ? 3.686   -6.699  11.938  1.00 31.11  ? 151 VAL C CA  1 
ATOM   5686  C  C   . VAL C 1 151 ? 3.903   -6.654  10.416  1.00 28.77  ? 151 VAL C C   1 
ATOM   5687  O  O   . VAL C 1 151 ? 3.311   -7.441  9.677   1.00 28.08  ? 151 VAL C O   1 
ATOM   5688  C  CB  . VAL C 1 151 ? 4.459   -7.868  12.585  1.00 32.66  ? 151 VAL C CB  1 
ATOM   5689  C  CG1 . VAL C 1 151 ? 5.943   -7.774  12.293  1.00 32.62  ? 151 VAL C CG1 1 
ATOM   5690  C  CG2 . VAL C 1 151 ? 4.168   -8.020  14.077  1.00 33.44  ? 151 VAL C CG2 1 
ATOM   5691  N  N   . ASP C 1 152 ? 4.796   -5.754  9.992   1.00 28.42  ? 152 ASP C N   1 
ATOM   5692  C  CA  . ASP C 1 152 ? 4.935   -5.294  8.614   1.00 32.06  ? 152 ASP C CA  1 
ATOM   5693  C  C   . ASP C 1 152 ? 6.417   -5.377  8.236   1.00 27.03  ? 152 ASP C C   1 
ATOM   5694  O  O   . ASP C 1 152 ? 7.259   -4.654  8.782   1.00 29.34  ? 152 ASP C O   1 
ATOM   5695  C  CB  . ASP C 1 152 ? 4.348   -3.886  8.446   1.00 38.57  ? 152 ASP C CB  1 
ATOM   5696  C  CG  . ASP C 1 152 ? 4.158   -3.401  7.010   1.00 41.83  ? 152 ASP C CG  1 
ATOM   5697  O  OD1 . ASP C 1 152 ? 5.074   -3.710  6.214   1.00 35.67  ? 152 ASP C OD1 1 
ATOM   5698  O  OD2 . ASP C 1 152 ? 3.123   -2.683  6.701   1.00 38.24  ? 152 ASP C OD2 1 
ATOM   5699  N  N   . GLY C 1 153 ? 6.725   -6.323  7.346   1.00 23.65  ? 153 GLY C N   1 
ATOM   5700  C  CA  . GLY C 1 153 ? 8.096   -6.532  6.889   1.00 24.35  ? 153 GLY C CA  1 
ATOM   5701  C  C   . GLY C 1 153 ? 8.561   -7.983  6.965   1.00 24.43  ? 153 GLY C C   1 
ATOM   5702  O  O   . GLY C 1 153 ? 9.579   -8.317  6.420   1.00 27.05  ? 153 GLY C O   1 
ATOM   5703  N  N   . THR C 1 154 ? 7.808   -8.837  7.649   1.00 23.02  ? 154 THR C N   1 
ATOM   5704  C  CA  . THR C 1 154 ? 8.285   -10.102 8.128   1.00 24.56  ? 154 THR C CA  1 
ATOM   5705  C  C   . THR C 1 154 ? 8.915   -10.943 7.025   1.00 26.26  ? 154 THR C C   1 
ATOM   5706  O  O   . THR C 1 154 ? 9.935   -11.600 7.214   1.00 25.89  ? 154 THR C O   1 
ATOM   5707  C  CB  . THR C 1 154 ? 7.066   -10.811 8.677   1.00 25.82  ? 154 THR C CB  1 
ATOM   5708  O  OG1 . THR C 1 154 ? 6.351   -9.885  9.501   1.00 23.46  ? 154 THR C OG1 1 
ATOM   5709  C  CG2 . THR C 1 154 ? 7.495   -12.113 9.342   1.00 27.86  ? 154 THR C CG2 1 
ATOM   5710  N  N   . GLU C 1 155 ? 8.241   -11.008 5.889   1.00 27.23  ? 155 GLU C N   1 
ATOM   5711  C  CA  . GLU C 1 155 ? 8.666   -11.897 4.829   1.00 27.35  ? 155 GLU C CA  1 
ATOM   5712  C  C   . GLU C 1 155 ? 9.534   -11.173 3.798   1.00 26.42  ? 155 GLU C C   1 
ATOM   5713  O  O   . GLU C 1 155 ? 9.802   -11.709 2.752   1.00 27.91  ? 155 GLU C O   1 
ATOM   5714  C  CB  . GLU C 1 155 ? 7.410   -12.515 4.212   1.00 30.84  ? 155 GLU C CB  1 
ATOM   5715  C  CG  . GLU C 1 155 ? 6.800   -13.630 5.066   1.00 32.92  ? 155 GLU C CG  1 
ATOM   5716  C  CD  . GLU C 1 155 ? 7.723   -14.814 5.304   1.00 33.09  ? 155 GLU C CD  1 
ATOM   5717  O  OE1 . GLU C 1 155 ? 8.148   -15.344 4.244   1.00 27.42  ? 155 GLU C OE1 1 
ATOM   5718  O  OE2 . GLU C 1 155 ? 8.002   -15.191 6.490   1.00 31.95  ? 155 GLU C OE2 1 
ATOM   5719  N  N   . ASN C 1 156 ? 10.030  -9.971  4.054   1.00 26.05  ? 156 ASN C N   1 
ATOM   5720  C  CA  . ASN C 1 156 ? 10.957  -9.388  3.108   1.00 26.53  ? 156 ASN C CA  1 
ATOM   5721  C  C   . ASN C 1 156 ? 12.112  -10.351 2.892   1.00 29.67  ? 156 ASN C C   1 
ATOM   5722  O  O   . ASN C 1 156 ? 12.446  -11.107 3.790   1.00 36.91  ? 156 ASN C O   1 
ATOM   5723  C  CB  . ASN C 1 156 ? 11.558  -8.075  3.574   1.00 25.13  ? 156 ASN C CB  1 
ATOM   5724  C  CG  . ASN C 1 156 ? 10.713  -6.907  3.162   1.00 27.71  ? 156 ASN C CG  1 
ATOM   5725  O  OD1 . ASN C 1 156 ? 10.165  -6.860  2.057   1.00 30.78  ? 156 ASN C OD1 1 
ATOM   5726  N  ND2 . ASN C 1 156 ? 10.581  -5.955  4.056   1.00 29.89  ? 156 ASN C ND2 1 
ATOM   5727  N  N   . PRO C 1 157 ? 12.786  -10.356 1.729   1.00 31.66  ? 157 PRO C N   1 
ATOM   5728  C  CA  . PRO C 1 157 ? 14.045  -11.099 1.577   1.00 35.75  ? 157 PRO C CA  1 
ATOM   5729  C  C   . PRO C 1 157 ? 15.204  -10.441 2.318   1.00 36.43  ? 157 PRO C C   1 
ATOM   5730  O  O   . PRO C 1 157 ? 15.155  -9.238  2.615   1.00 33.18  ? 157 PRO C O   1 
ATOM   5731  C  CB  . PRO C 1 157 ? 14.303  -11.104 0.058   1.00 35.32  ? 157 PRO C CB  1 
ATOM   5732  C  CG  . PRO C 1 157 ? 13.603  -9.856  -0.409  1.00 36.10  ? 157 PRO C CG  1 
ATOM   5733  C  CD  . PRO C 1 157 ? 12.357  -9.709  0.480   1.00 34.91  ? 157 PRO C CD  1 
ATOM   5734  N  N   . THR C 1 158 ? 16.239  -11.255 2.597   1.00 38.35  ? 158 THR C N   1 
ATOM   5735  C  CA  . THR C 1 158 ? 17.422  -10.763 3.290   1.00 41.10  ? 158 THR C CA  1 
ATOM   5736  C  C   . THR C 1 158 ? 18.676  -11.249 2.560   1.00 38.94  ? 158 THR C C   1 
ATOM   5737  O  O   . THR C 1 158 ? 18.620  -12.209 1.780   1.00 35.77  ? 158 THR C O   1 
ATOM   5738  C  CB  . THR C 1 158 ? 17.408  -11.102 4.786   1.00 38.62  ? 158 THR C CB  1 
ATOM   5739  O  OG1 . THR C 1 158 ? 17.096  -12.482 4.843   1.00 39.73  ? 158 THR C OG1 1 
ATOM   5740  C  CG2 . THR C 1 158 ? 16.345  -10.352 5.562   1.00 38.34  ? 158 THR C CG2 1 
ATOM   5741  N  N   . GLY C 1 159 ? 19.773  -10.500 2.806   1.00 42.98  ? 159 GLY C N   1 
ATOM   5742  C  CA  . GLY C 1 159 ? 21.112  -10.788 2.307   1.00 45.32  ? 159 GLY C CA  1 
ATOM   5743  C  C   . GLY C 1 159 ? 21.119  -11.106 0.811   1.00 49.72  ? 159 GLY C C   1 
ATOM   5744  O  O   . GLY C 1 159 ? 20.585  -10.340 0.004   1.00 57.43  ? 159 GLY C O   1 
ATOM   5745  N  N   . ALA C 1 160 ? 21.721  -12.251 0.454   1.00 51.21  ? 160 ALA C N   1 
ATOM   5746  C  CA  . ALA C 1 160 ? 21.889  -12.645 -0.938  1.00 51.63  ? 160 ALA C CA  1 
ATOM   5747  C  C   . ALA C 1 160 ? 20.532  -12.621 -1.659  1.00 49.91  ? 160 ALA C C   1 
ATOM   5748  O  O   . ALA C 1 160 ? 20.417  -12.077 -2.754  1.00 48.81  ? 160 ALA C O   1 
ATOM   5749  C  CB  . ALA C 1 160 ? 22.590  -14.000 -1.033  1.00 46.69  ? 160 ALA C CB  1 
ATOM   5750  N  N   . ALA C 1 161 ? 19.471  -13.145 -1.027  1.00 45.00  ? 161 ALA C N   1 
ATOM   5751  C  CA  . ALA C 1 161 ? 18.189  -13.255 -1.707  1.00 42.33  ? 161 ALA C CA  1 
ATOM   5752  C  C   . ALA C 1 161 ? 17.682  -11.860 -2.072  1.00 42.69  ? 161 ALA C C   1 
ATOM   5753  O  O   . ALA C 1 161 ? 17.069  -11.678 -3.121  1.00 41.82  ? 161 ALA C O   1 
ATOM   5754  C  CB  . ALA C 1 161 ? 17.203  -14.016 -0.840  1.00 45.70  ? 161 ALA C CB  1 
ATOM   5755  N  N   . ALA C 1 162 ? 17.937  -10.890 -1.186  1.00 40.77  ? 162 ALA C N   1 
ATOM   5756  C  CA  . ALA C 1 162 ? 17.487  -9.525  -1.383  1.00 39.67  ? 162 ALA C CA  1 
ATOM   5757  C  C   . ALA C 1 162 ? 18.258  -8.847  -2.503  1.00 37.35  ? 162 ALA C C   1 
ATOM   5758  O  O   . ALA C 1 162 ? 17.613  -8.235  -3.345  1.00 35.19  ? 162 ALA C O   1 
ATOM   5759  C  CB  . ALA C 1 162 ? 17.644  -8.772  -0.103  1.00 42.06  ? 162 ALA C CB  1 
ATOM   5760  N  N   . ARG C 1 163 ? 19.607  -8.991  -2.499  1.00 44.38  ? 163 ARG C N   1 
ATOM   5761  C  CA  . ARG C 1 163 ? 20.514  -8.537  -3.570  1.00 39.11  ? 163 ARG C CA  1 
ATOM   5762  C  C   . ARG C 1 163 ? 19.907  -8.971  -4.907  1.00 33.64  ? 163 ARG C C   1 
ATOM   5763  O  O   . ARG C 1 163 ? 19.724  -8.147  -5.794  1.00 34.68  ? 163 ARG C O   1 
ATOM   5764  C  CB  . ARG C 1 163 ? 22.015  -8.909  -3.397  1.00 40.12  ? 163 ARG C CB  1 
ATOM   5765  C  CG  . ARG C 1 163 ? 22.975  -8.075  -2.521  1.00 46.60  ? 163 ARG C CG  1 
ATOM   5766  C  CD  . ARG C 1 163 ? 24.293  -8.756  -1.978  1.00 45.35  ? 163 ARG C CD  1 
ATOM   5767  N  N   . ARG C 1 164 ? 19.500  -10.235 -5.028  1.00 31.98  ? 164 ARG C N   1 
ATOM   5768  C  CA  . ARG C 1 164 ? 19.067  -10.796 -6.305  1.00 35.53  ? 164 ARG C CA  1 
ATOM   5769  C  C   . ARG C 1 164 ? 17.661  -10.337 -6.683  1.00 35.72  ? 164 ARG C C   1 
ATOM   5770  O  O   . ARG C 1 164 ? 17.339  -10.280 -7.864  1.00 32.42  ? 164 ARG C O   1 
ATOM   5771  C  CB  . ARG C 1 164 ? 19.143  -12.332 -6.381  1.00 44.75  ? 164 ARG C CB  1 
ATOM   5772  C  CG  . ARG C 1 164 ? 20.172  -12.876 -7.376  1.00 65.84  ? 164 ARG C CG  1 
ATOM   5773  C  CD  . ARG C 1 164 ? 20.664  -14.326 -7.161  1.00 78.17  ? 164 ARG C CD  1 
ATOM   5774  N  NE  . ARG C 1 164 ? 19.608  -15.155 -6.565  1.00 81.82  ? 164 ARG C NE  1 
ATOM   5775  C  CZ  . ARG C 1 164 ? 19.637  -15.683 -5.342  1.00 85.42  ? 164 ARG C CZ  1 
ATOM   5776  N  NH1 . ARG C 1 164 ? 20.782  -15.770 -4.684  1.00 87.25  ? 164 ARG C NH1 1 
ATOM   5777  N  NH2 . ARG C 1 164 ? 18.526  -16.164 -4.797  1.00 88.53  ? 164 ARG C NH2 1 
ATOM   5778  N  N   . ALA C 1 165 ? 16.797  -10.035 -5.702  1.00 36.74  ? 165 ALA C N   1 
ATOM   5779  C  CA  . ALA C 1 165 ? 15.421  -9.694  -6.031  1.00 31.68  ? 165 ALA C CA  1 
ATOM   5780  C  C   . ALA C 1 165 ? 15.319  -8.238  -6.463  1.00 29.99  ? 165 ALA C C   1 
ATOM   5781  O  O   . ALA C 1 165 ? 14.375  -7.872  -7.139  1.00 26.68  ? 165 ALA C O   1 
ATOM   5782  C  CB  . ALA C 1 165 ? 14.541  -9.979  -4.854  1.00 29.63  ? 165 ALA C CB  1 
ATOM   5783  N  N   . VAL C 1 166 ? 16.304  -7.415  -6.098  1.00 32.70  ? 166 VAL C N   1 
ATOM   5784  C  CA  . VAL C 1 166 ? 16.149  -5.967  -6.070  1.00 33.74  ? 166 VAL C CA  1 
ATOM   5785  C  C   . VAL C 1 166 ? 17.044  -5.264  -7.091  1.00 32.13  ? 166 VAL C C   1 
ATOM   5786  O  O   . VAL C 1 166 ? 16.644  -4.250  -7.685  1.00 28.91  ? 166 VAL C O   1 
ATOM   5787  C  CB  . VAL C 1 166 ? 16.482  -5.508  -4.636  1.00 37.27  ? 166 VAL C CB  1 
ATOM   5788  C  CG1 . VAL C 1 166 ? 16.867  -4.048  -4.605  1.00 35.57  ? 166 VAL C CG1 1 
ATOM   5789  C  CG2 . VAL C 1 166 ? 15.352  -5.803  -3.649  1.00 37.80  ? 166 VAL C CG2 1 
ATOM   5790  N  N   . LEU C 1 167 ? 18.278  -5.754  -7.260  1.00 31.16  ? 167 LEU C N   1 
ATOM   5791  C  CA  . LEU C 1 167 ? 19.263  -5.050  -8.081  1.00 35.63  ? 167 LEU C CA  1 
ATOM   5792  C  C   . LEU C 1 167 ? 19.275  -5.550  -9.534  1.00 35.02  ? 167 LEU C C   1 
ATOM   5793  O  O   . LEU C 1 167 ? 19.327  -6.748  -9.787  1.00 35.85  ? 167 LEU C O   1 
ATOM   5794  C  CB  . LEU C 1 167 ? 20.629  -5.218  -7.426  1.00 36.81  ? 167 LEU C CB  1 
ATOM   5795  C  CG  . LEU C 1 167 ? 20.814  -4.585  -6.043  1.00 42.45  ? 167 LEU C CG  1 
ATOM   5796  C  CD1 . LEU C 1 167 ? 22.155  -4.957  -5.437  1.00 39.73  ? 167 LEU C CD1 1 
ATOM   5797  C  CD2 . LEU C 1 167 ? 20.675  -3.072  -6.149  1.00 45.48  ? 167 LEU C CD2 1 
ATOM   5798  N  N   . VAL C 1 168 ? 19.194  -4.608  -10.474 1.00 31.89  ? 168 VAL C N   1 
ATOM   5799  C  CA  . VAL C 1 168 ? 19.368  -4.877  -11.889 1.00 33.48  ? 168 VAL C CA  1 
ATOM   5800  C  C   . VAL C 1 168 ? 20.750  -5.489  -12.088 1.00 33.24  ? 168 VAL C C   1 
ATOM   5801  O  O   . VAL C 1 168 ? 21.715  -5.032  -11.474 1.00 34.71  ? 168 VAL C O   1 
ATOM   5802  C  CB  . VAL C 1 168 ? 19.248  -3.549  -12.673 1.00 35.37  ? 168 VAL C CB  1 
ATOM   5803  C  CG1 . VAL C 1 168 ? 19.652  -3.657  -14.136 1.00 32.70  ? 168 VAL C CG1 1 
ATOM   5804  C  CG2 . VAL C 1 168 ? 17.848  -2.969  -12.552 1.00 34.97  ? 168 VAL C CG2 1 
ATOM   5805  N  N   . GLY C 1 169 ? 20.817  -6.531  -12.933 1.00 33.69  ? 169 GLY C N   1 
ATOM   5806  C  CA  . GLY C 1 169 ? 22.073  -7.200  -13.259 1.00 37.86  ? 169 GLY C CA  1 
ATOM   5807  C  C   . GLY C 1 169 ? 22.370  -7.238  -14.762 1.00 44.74  ? 169 GLY C C   1 
ATOM   5808  O  O   . GLY C 1 169 ? 22.222  -6.214  -15.446 1.00 46.73  ? 169 GLY C O   1 
ATOM   5809  N  N   . ALA C 1 170 ? 22.770  -8.435  -15.257 1.00 46.21  ? 170 ALA C N   1 
ATOM   5810  C  CA  . ALA C 1 170 ? 23.254  -8.669  -16.624 1.00 46.44  ? 170 ALA C CA  1 
ATOM   5811  C  C   . ALA C 1 170 ? 22.174  -8.426  -17.680 1.00 44.94  ? 170 ALA C C   1 
ATOM   5812  O  O   . ALA C 1 170 ? 22.492  -8.109  -18.814 1.00 53.76  ? 170 ALA C O   1 
ATOM   5813  C  CB  . ALA C 1 170 ? 23.775  -10.084 -16.769 1.00 43.59  ? 170 ALA C CB  1 
ATOM   5814  N  N   . GLU C 1 171 ? 20.899  -8.521  -17.288 1.00 39.88  ? 171 GLU C N   1 
ATOM   5815  C  CA  . GLU C 1 171 ? 19.785  -8.337  -18.198 1.00 39.92  ? 171 GLU C CA  1 
ATOM   5816  C  C   . GLU C 1 171 ? 19.700  -6.894  -18.678 1.00 41.70  ? 171 GLU C C   1 
ATOM   5817  O  O   . GLU C 1 171 ? 18.988  -6.662  -19.656 1.00 42.99  ? 171 GLU C O   1 
ATOM   5818  C  CB  . GLU C 1 171 ? 18.436  -8.815  -17.634 1.00 43.81  ? 171 GLU C CB  1 
ATOM   5819  C  CG  . GLU C 1 171 ? 17.760  -7.941  -16.569 1.00 50.59  ? 171 GLU C CG  1 
ATOM   5820  C  CD  . GLU C 1 171 ? 18.376  -7.830  -15.163 1.00 52.74  ? 171 GLU C CD  1 
ATOM   5821  O  OE1 . GLU C 1 171 ? 19.436  -8.470  -14.923 1.00 48.38  ? 171 GLU C OE1 1 
ATOM   5822  O  OE2 . GLU C 1 171 ? 17.822  -7.079  -14.297 1.00 47.64  ? 171 GLU C OE2 1 
ATOM   5823  N  N   . ASP C 1 172 ? 20.375  -5.940  -17.996 1.00 46.17  ? 172 ASP C N   1 
ATOM   5824  C  CA  . ASP C 1 172 ? 20.356  -4.529  -18.400 1.00 51.35  ? 172 ASP C CA  1 
ATOM   5825  C  C   . ASP C 1 172 ? 21.672  -3.893  -17.987 1.00 48.58  ? 172 ASP C C   1 
ATOM   5826  O  O   . ASP C 1 172 ? 21.713  -2.958  -17.202 1.00 55.58  ? 172 ASP C O   1 
ATOM   5827  C  CB  . ASP C 1 172 ? 19.145  -3.736  -17.909 1.00 46.27  ? 172 ASP C CB  1 
ATOM   5828  C  CG  . ASP C 1 172 ? 18.928  -2.370  -18.555 1.00 41.83  ? 172 ASP C CG  1 
ATOM   5829  O  OD1 . ASP C 1 172 ? 19.816  -1.938  -19.284 1.00 52.19  ? 172 ASP C OD1 1 
ATOM   5830  O  OD2 . ASP C 1 172 ? 17.887  -1.745  -18.334 1.00 41.91  ? 172 ASP C OD2 1 
ATOM   5831  N  N   . PRO C 1 173 ? 22.779  -4.370  -18.574 1.00 44.24  ? 173 PRO C N   1 
ATOM   5832  C  CA  . PRO C 1 173 ? 24.095  -4.185  -17.961 1.00 44.89  ? 173 PRO C CA  1 
ATOM   5833  C  C   . PRO C 1 173 ? 24.545  -2.732  -17.827 1.00 41.54  ? 173 PRO C C   1 
ATOM   5834  O  O   . PRO C 1 173 ? 25.312  -2.390  -16.940 1.00 37.73  ? 173 PRO C O   1 
ATOM   5835  C  CB  . PRO C 1 173 ? 25.024  -5.009  -18.865 1.00 41.40  ? 173 PRO C CB  1 
ATOM   5836  C  CG  . PRO C 1 173 ? 24.260  -5.187  -20.158 1.00 40.91  ? 173 PRO C CG  1 
ATOM   5837  C  CD  . PRO C 1 173 ? 22.787  -5.109  -19.844 1.00 40.05  ? 173 PRO C CD  1 
ATOM   5838  N  N   . ALA C 1 174 ? 24.041  -1.858  -18.693 1.00 37.65  ? 174 ALA C N   1 
ATOM   5839  C  CA  . ALA C 1 174 ? 24.359  -0.450  -18.559 1.00 36.54  ? 174 ALA C CA  1 
ATOM   5840  C  C   . ALA C 1 174 ? 23.865  0.136   -17.226 1.00 40.16  ? 174 ALA C C   1 
ATOM   5841  O  O   . ALA C 1 174 ? 24.320  1.188   -16.819 1.00 37.89  ? 174 ALA C O   1 
ATOM   5842  C  CB  . ALA C 1 174 ? 23.729  0.230   -19.739 1.00 40.52  ? 174 ALA C CB  1 
ATOM   5843  N  N   . PHE C 1 175 ? 22.887  -0.506  -16.557 1.00 44.61  ? 175 PHE C N   1 
ATOM   5844  C  CA  . PHE C 1 175 ? 22.191  0.074   -15.410 1.00 33.77  ? 175 PHE C CA  1 
ATOM   5845  C  C   . PHE C 1 175 ? 22.256  -0.851  -14.209 1.00 30.01  ? 175 PHE C C   1 
ATOM   5846  O  O   . PHE C 1 175 ? 21.616  -0.625  -13.214 1.00 32.29  ? 175 PHE C O   1 
ATOM   5847  C  CB  . PHE C 1 175 ? 20.734  0.329   -15.815 1.00 30.92  ? 175 PHE C CB  1 
ATOM   5848  C  CG  . PHE C 1 175 ? 20.647  1.444   -16.830 1.00 31.21  ? 175 PHE C CG  1 
ATOM   5849  C  CD1 . PHE C 1 175 ? 21.009  2.722   -16.483 1.00 32.91  ? 175 PHE C CD1 1 
ATOM   5850  C  CD2 . PHE C 1 175 ? 20.229  1.215   -18.118 1.00 36.47  ? 175 PHE C CD2 1 
ATOM   5851  C  CE1 . PHE C 1 175 ? 20.928  3.768   -17.388 1.00 32.78  ? 175 PHE C CE1 1 
ATOM   5852  C  CE2 . PHE C 1 175 ? 20.185  2.255   -19.032 1.00 38.80  ? 175 PHE C CE2 1 
ATOM   5853  C  CZ  . PHE C 1 175 ? 20.542  3.531   -18.666 1.00 35.23  ? 175 PHE C CZ  1 
ATOM   5854  N  N   . ALA C 1 176 ? 23.071  -1.883  -14.297 1.00 30.67  ? 176 ALA C N   1 
ATOM   5855  C  CA  . ALA C 1 176 ? 23.319  -2.759  -13.176 1.00 28.55  ? 176 ALA C CA  1 
ATOM   5856  C  C   . ALA C 1 176 ? 23.652  -1.938  -11.923 1.00 29.26  ? 176 ALA C C   1 
ATOM   5857  O  O   . ALA C 1 176 ? 24.379  -0.932  -11.987 1.00 27.50  ? 176 ALA C O   1 
ATOM   5858  C  CB  . ALA C 1 176 ? 24.397  -3.735  -13.586 1.00 25.38  ? 176 ALA C CB  1 
ATOM   5859  N  N   . GLY C 1 177 ? 23.022  -2.367  -10.805 1.00 31.35  ? 177 GLY C N   1 
ATOM   5860  C  CA  . GLY C 1 177 ? 23.151  -1.724  -9.498  1.00 36.65  ? 177 GLY C CA  1 
ATOM   5861  C  C   . GLY C 1 177 ? 21.980  -0.797  -9.162  1.00 33.06  ? 177 GLY C C   1 
ATOM   5862  O  O   . GLY C 1 177 ? 21.841  -0.238  -8.038  1.00 36.94  ? 177 GLY C O   1 
ATOM   5863  N  N   . GLY C 1 178 ? 21.174  -0.607  -10.210 1.00 32.69  ? 178 GLY C N   1 
ATOM   5864  C  CA  . GLY C 1 178 ? 19.946  0.151   -10.104 1.00 34.94  ? 178 GLY C CA  1 
ATOM   5865  C  C   . GLY C 1 178 ? 18.816  -0.722  -9.564  1.00 33.01  ? 178 GLY C C   1 
ATOM   5866  O  O   . GLY C 1 178 ? 18.999  -1.923  -9.317  1.00 26.71  ? 178 GLY C O   1 
ATOM   5867  N  N   . SER C 1 179 ? 17.671  -0.057  -9.325  1.00 31.93  ? 179 SER C N   1 
ATOM   5868  C  CA  . SER C 1 179 ? 16.478  -0.727  -8.876  1.00 25.88  ? 179 SER C CA  1 
ATOM   5869  C  C   . SER C 1 179 ? 15.277  0.102   -9.299  1.00 25.58  ? 179 SER C C   1 
ATOM   5870  O  O   . SER C 1 179 ? 15.424  1.232   -9.723  1.00 23.04  ? 179 SER C O   1 
ATOM   5871  C  CB  . SER C 1 179 ? 16.522  -1.008  -7.427  1.00 24.76  ? 179 SER C CB  1 
ATOM   5872  O  OG  . SER C 1 179 ? 15.470  -1.921  -7.113  1.00 27.90  ? 179 SER C OG  1 
ATOM   5873  N  N   . TYR C 1 180 ? 14.090  -0.517  -9.273  1.00 28.78  ? 180 TYR C N   1 
ATOM   5874  C  CA  . TYR C 1 180 ? 12.855  0.173   -9.572  1.00 26.28  ? 180 TYR C CA  1 
ATOM   5875  C  C   . TYR C 1 180 ? 12.050  0.270   -8.280  1.00 27.48  ? 180 TYR C C   1 
ATOM   5876  O  O   . TYR C 1 180 ? 11.751  -0.761  -7.653  1.00 31.01  ? 180 TYR C O   1 
ATOM   5877  C  CB  . TYR C 1 180 ? 12.078  -0.556  -10.674 1.00 29.16  ? 180 TYR C CB  1 
ATOM   5878  C  CG  . TYR C 1 180 ? 12.764  -0.577  -12.030 1.00 31.15  ? 180 TYR C CG  1 
ATOM   5879  C  CD1 . TYR C 1 180 ? 13.662  -1.592  -12.338 1.00 32.33  ? 180 TYR C CD1 1 
ATOM   5880  C  CD2 . TYR C 1 180 ? 12.498  0.377   -13.002 1.00 29.89  ? 180 TYR C CD2 1 
ATOM   5881  C  CE1 . TYR C 1 180 ? 14.334  -1.625  -13.548 1.00 30.74  ? 180 TYR C CE1 1 
ATOM   5882  C  CE2 . TYR C 1 180 ? 13.150  0.344   -14.222 1.00 31.59  ? 180 TYR C CE2 1 
ATOM   5883  C  CZ  . TYR C 1 180 ? 14.078  -0.658  -14.500 1.00 33.38  ? 180 TYR C CZ  1 
ATOM   5884  O  OH  . TYR C 1 180 ? 14.771  -0.774  -15.692 1.00 28.09  ? 180 TYR C OH  1 
ATOM   5885  N  N   . ALA C 1 181 ? 11.641  1.517   -7.960  1.00 24.98  ? 181 ALA C N   1 
ATOM   5886  C  CA  . ALA C 1 181 ? 10.784  1.800   -6.817  1.00 24.64  ? 181 ALA C CA  1 
ATOM   5887  C  C   . ALA C 1 181 ? 9.383   2.212   -7.248  1.00 22.89  ? 181 ALA C C   1 
ATOM   5888  O  O   . ALA C 1 181 ? 9.207   3.083   -8.097  1.00 23.64  ? 181 ALA C O   1 
ATOM   5889  C  CB  . ALA C 1 181 ? 11.413  2.881   -5.971  1.00 24.49  ? 181 ALA C CB  1 
ATOM   5890  N  N   . VAL C 1 182 ? 8.394   1.612   -6.586  1.00 25.29  ? 182 VAL C N   1 
ATOM   5891  C  CA  . VAL C 1 182 ? 6.998   2.005   -6.709  1.00 27.14  ? 182 VAL C CA  1 
ATOM   5892  C  C   . VAL C 1 182 ? 6.542   2.544   -5.380  1.00 24.60  ? 182 VAL C C   1 
ATOM   5893  O  O   . VAL C 1 182 ? 6.707   1.854   -4.383  1.00 22.48  ? 182 VAL C O   1 
ATOM   5894  C  CB  . VAL C 1 182 ? 6.057   0.849   -7.084  1.00 33.75  ? 182 VAL C CB  1 
ATOM   5895  C  CG1 . VAL C 1 182 ? 4.607   1.326   -7.143  1.00 31.11  ? 182 VAL C CG1 1 
ATOM   5896  C  CG2 . VAL C 1 182 ? 6.500   0.171   -8.391  1.00 39.71  ? 182 VAL C CG2 1 
ATOM   5897  N  N   . VAL C 1 183 ? 5.954   3.745   -5.406  1.00 24.22  ? 183 VAL C N   1 
ATOM   5898  C  CA  . VAL C 1 183 ? 5.421   4.327   -4.188  1.00 24.30  ? 183 VAL C CA  1 
ATOM   5899  C  C   . VAL C 1 183 ? 3.923   4.491   -4.340  1.00 22.06  ? 183 VAL C C   1 
ATOM   5900  O  O   . VAL C 1 183 ? 3.444   4.802   -5.421  1.00 23.00  ? 183 VAL C O   1 
ATOM   5901  C  CB  . VAL C 1 183 ? 6.071   5.646   -3.778  1.00 23.08  ? 183 VAL C CB  1 
ATOM   5902  C  CG1 . VAL C 1 183 ? 7.555   5.424   -3.578  1.00 24.65  ? 183 VAL C CG1 1 
ATOM   5903  C  CG2 . VAL C 1 183 ? 5.807   6.753   -4.770  1.00 24.05  ? 183 VAL C CG2 1 
ATOM   5904  N  N   . GLN C 1 184 ? 3.210   4.225   -3.254  1.00 22.31  ? 184 GLN C N   1 
ATOM   5905  C  CA  . GLN C 1 184 ? 1.786   4.531   -3.184  1.00 22.75  ? 184 GLN C CA  1 
ATOM   5906  C  C   . GLN C 1 184 ? 1.439   4.942   -1.767  1.00 21.42  ? 184 GLN C C   1 
ATOM   5907  O  O   . GLN C 1 184 ? 1.743   4.197   -0.835  1.00 21.50  ? 184 GLN C O   1 
ATOM   5908  C  CB  . GLN C 1 184 ? 0.947   3.283   -3.417  1.00 25.04  ? 184 GLN C CB  1 
ATOM   5909  C  CG  . GLN C 1 184 ? 0.972   2.752   -4.842  1.00 24.38  ? 184 GLN C CG  1 
ATOM   5910  C  CD  . GLN C 1 184 ? -0.012  1.628   -4.934  1.00 25.22  ? 184 GLN C CD  1 
ATOM   5911  O  OE1 . GLN C 1 184 ? 0.139   0.598   -4.247  1.00 21.22  ? 184 GLN C OE1 1 
ATOM   5912  N  NE2 . GLN C 1 184 ? -1.081  1.946   -5.654  1.00 29.80  ? 184 GLN C NE2 1 
ATOM   5913  N  N   . LYS C 1 185 ? 0.871   6.138   -1.610  1.00 20.29  ? 185 LYS C N   1 
ATOM   5914  C  CA  . LYS C 1 185 ? 0.405   6.552   -0.299  1.00 23.35  ? 185 LYS C CA  1 
ATOM   5915  C  C   . LYS C 1 185 ? -1.008  6.005   -0.050  1.00 25.82  ? 185 LYS C C   1 
ATOM   5916  O  O   . LYS C 1 185 ? -1.898  6.245   -0.867  1.00 25.33  ? 185 LYS C O   1 
ATOM   5917  C  CB  . LYS C 1 185 ? 0.420   8.082   -0.257  1.00 25.07  ? 185 LYS C CB  1 
ATOM   5918  C  CG  . LYS C 1 185 ? -0.151  8.625   1.042   1.00 28.07  ? 185 LYS C CG  1 
ATOM   5919  C  CD  . LYS C 1 185 ? 0.296   10.030  1.422   1.00 29.06  ? 185 LYS C CD  1 
ATOM   5920  C  CE  . LYS C 1 185 ? -0.244  10.936  0.389   1.00 28.28  ? 185 LYS C CE  1 
ATOM   5921  N  NZ  . LYS C 1 185 ? 0.057   12.245  0.912   1.00 29.37  ? 185 LYS C NZ  1 
ATOM   5922  N  N   . TYR C 1 186 ? -1.213  5.298   1.073   1.00 23.35  ? 186 TYR C N   1 
ATOM   5923  C  CA  . TYR C 1 186 ? -2.499  4.708   1.390   1.00 24.63  ? 186 TYR C CA  1 
ATOM   5924  C  C   . TYR C 1 186 ? -3.053  5.393   2.630   1.00 29.30  ? 186 TYR C C   1 
ATOM   5925  O  O   . TYR C 1 186 ? -2.292  5.650   3.569   1.00 33.09  ? 186 TYR C O   1 
ATOM   5926  C  CB  . TYR C 1 186 ? -2.474  3.205   1.676   1.00 23.66  ? 186 TYR C CB  1 
ATOM   5927  C  CG  . TYR C 1 186 ? -2.324  2.319   0.437   1.00 26.94  ? 186 TYR C CG  1 
ATOM   5928  C  CD1 . TYR C 1 186 ? -1.078  2.044   -0.112  1.00 27.91  ? 186 TYR C CD1 1 
ATOM   5929  C  CD2 . TYR C 1 186 ? -3.423  1.726   -0.182  1.00 29.95  ? 186 TYR C CD2 1 
ATOM   5930  C  CE1 . TYR C 1 186 ? -0.922  1.254   -1.239  1.00 31.26  ? 186 TYR C CE1 1 
ATOM   5931  C  CE2 . TYR C 1 186 ? -3.276  0.931   -1.310  1.00 28.91  ? 186 TYR C CE2 1 
ATOM   5932  C  CZ  . TYR C 1 186 ? -2.027  0.687   -1.841  1.00 28.98  ? 186 TYR C CZ  1 
ATOM   5933  O  OH  . TYR C 1 186 ? -1.852  -0.084  -2.951  1.00 28.66  ? 186 TYR C OH  1 
ATOM   5934  N  N   . LEU C 1 187 ? -4.377  5.637   2.621   1.00 29.05  ? 187 LEU C N   1 
ATOM   5935  C  CA  . LEU C 1 187 ? -5.093  6.090   3.802   1.00 27.07  ? 187 LEU C CA  1 
ATOM   5936  C  C   . LEU C 1 187 ? -6.057  5.002   4.246   1.00 28.39  ? 187 LEU C C   1 
ATOM   5937  O  O   . LEU C 1 187 ? -6.715  4.380   3.425   1.00 28.39  ? 187 LEU C O   1 
ATOM   5938  C  CB  . LEU C 1 187 ? -5.823  7.371   3.455   1.00 24.75  ? 187 LEU C CB  1 
ATOM   5939  C  CG  . LEU C 1 187 ? -4.963  8.618   3.292   1.00 25.05  ? 187 LEU C CG  1 
ATOM   5940  C  CD1 . LEU C 1 187 ? -5.884  9.784   2.961   1.00 24.82  ? 187 LEU C CD1 1 
ATOM   5941  C  CD2 . LEU C 1 187 ? -4.223  8.931   4.589   1.00 26.23  ? 187 LEU C CD2 1 
ATOM   5942  N  N   . HIS C 1 188 ? -6.146  4.787   5.547   1.00 24.64  ? 188 HIS C N   1 
ATOM   5943  C  CA  . HIS C 1 188 ? -6.948  3.688   6.025   1.00 25.43  ? 188 HIS C CA  1 
ATOM   5944  C  C   . HIS C 1 188 ? -8.244  4.172   6.646   1.00 26.09  ? 188 HIS C C   1 
ATOM   5945  O  O   . HIS C 1 188 ? -8.267  5.252   7.210   1.00 26.98  ? 188 HIS C O   1 
ATOM   5946  C  CB  . HIS C 1 188 ? -6.173  2.909   7.088   1.00 27.02  ? 188 HIS C CB  1 
ATOM   5947  C  CG  . HIS C 1 188 ? -4.994  2.216   6.529   1.00 27.90  ? 188 HIS C CG  1 
ATOM   5948  N  ND1 . HIS C 1 188 ? -5.105  1.168   5.645   1.00 26.87  ? 188 HIS C ND1 1 
ATOM   5949  C  CD2 . HIS C 1 188 ? -3.691  2.433   6.709   1.00 30.32  ? 188 HIS C CD2 1 
ATOM   5950  C  CE1 . HIS C 1 188 ? -3.891  0.750   5.330   1.00 30.08  ? 188 HIS C CE1 1 
ATOM   5951  N  NE2 . HIS C 1 188 ? -3.010  1.508   5.952   1.00 28.83  ? 188 HIS C NE2 1 
ATOM   5952  N  N   . ASP C 1 189 ? -9.281  3.321   6.596   1.00 28.31  ? 189 ASP C N   1 
ATOM   5953  C  CA  . ASP C 1 189 ? -10.510 3.525   7.349   1.00 29.88  ? 189 ASP C CA  1 
ATOM   5954  C  C   . ASP C 1 189 ? -10.422 2.687   8.620   1.00 30.39  ? 189 ASP C C   1 
ATOM   5955  O  O   . ASP C 1 189 ? -10.821 1.507   8.651   1.00 27.54  ? 189 ASP C O   1 
ATOM   5956  C  CB  . ASP C 1 189 ? -11.763 3.176   6.563   1.00 29.95  ? 189 ASP C CB  1 
ATOM   5957  C  CG  . ASP C 1 189 ? -13.100 3.465   7.242   1.00 29.24  ? 189 ASP C CG  1 
ATOM   5958  O  OD1 . ASP C 1 189 ? -13.140 3.867   8.436   1.00 26.36  ? 189 ASP C OD1 1 
ATOM   5959  O  OD2 . ASP C 1 189 ? -14.097 3.326   6.526   1.00 37.08  ? 189 ASP C OD2 1 
ATOM   5960  N  N   . ILE C 1 190 ? -9.898  3.354   9.658   1.00 28.73  ? 190 ILE C N   1 
ATOM   5961  C  CA  . ILE C 1 190 ? -9.650  2.763   10.957  1.00 28.81  ? 190 ILE C CA  1 
ATOM   5962  C  C   . ILE C 1 190 ? -10.973 2.374   11.614  1.00 32.39  ? 190 ILE C C   1 
ATOM   5963  O  O   . ILE C 1 190 ? -11.010 1.314   12.255  1.00 28.42  ? 190 ILE C O   1 
ATOM   5964  C  CB  . ILE C 1 190 ? -8.802  3.713   11.819  1.00 28.45  ? 190 ILE C CB  1 
ATOM   5965  C  CG1 . ILE C 1 190 ? -7.376  3.774   11.316  1.00 29.28  ? 190 ILE C CG1 1 
ATOM   5966  C  CG2 . ILE C 1 190 ? -8.840  3.330   13.278  1.00 31.13  ? 190 ILE C CG2 1 
ATOM   5967  C  CD1 . ILE C 1 190 ? -6.645  2.445   11.327  1.00 28.93  ? 190 ILE C CD1 1 
ATOM   5968  N  N   . ASP C 1 191 ? -12.043 3.172   11.422  1.00 32.70  ? 191 ASP C N   1 
ATOM   5969  C  CA  . ASP C 1 191 ? -13.301 2.895   12.112  1.00 31.81  ? 191 ASP C CA  1 
ATOM   5970  C  C   . ASP C 1 191 ? -13.841 1.554   11.644  1.00 28.24  ? 191 ASP C C   1 
ATOM   5971  O  O   . ASP C 1 191 ? -14.178 0.689   12.435  1.00 28.99  ? 191 ASP C O   1 
ATOM   5972  C  CB  . ASP C 1 191 ? -14.366 3.946   11.900  1.00 31.69  ? 191 ASP C CB  1 
ATOM   5973  C  CG  . ASP C 1 191 ? -14.016 5.367   12.278  1.00 38.45  ? 191 ASP C CG  1 
ATOM   5974  O  OD1 . ASP C 1 191 ? -13.478 5.560   13.381  1.00 40.70  ? 191 ASP C OD1 1 
ATOM   5975  O  OD2 . ASP C 1 191 ? -14.313 6.259   11.451  1.00 55.36  ? 191 ASP C OD2 1 
ATOM   5976  N  N   . ALA C 1 192 ? -13.853 1.369   10.334  1.00 25.67  ? 192 ALA C N   1 
ATOM   5977  C  CA  . ALA C 1 192 ? -14.325 0.135   9.737   1.00 25.12  ? 192 ALA C CA  1 
ATOM   5978  C  C   . ALA C 1 192 ? -13.486 -1.032  10.203  1.00 26.95  ? 192 ALA C C   1 
ATOM   5979  O  O   . ALA C 1 192 ? -13.986 -2.107  10.461  1.00 28.92  ? 192 ALA C O   1 
ATOM   5980  C  CB  . ALA C 1 192 ? -14.225 0.246   8.231   1.00 25.93  ? 192 ALA C CB  1 
ATOM   5981  N  N   . TRP C 1 193 ? -12.179 -0.814  10.214  1.00 32.08  ? 193 TRP C N   1 
ATOM   5982  C  CA  . TRP C 1 193 ? -11.225 -1.864  10.476  1.00 29.33  ? 193 TRP C CA  1 
ATOM   5983  C  C   . TRP C 1 193 ? -11.369 -2.331  11.913  1.00 27.97  ? 193 TRP C C   1 
ATOM   5984  O  O   . TRP C 1 193 ? -11.397 -3.542  12.139  1.00 26.63  ? 193 TRP C O   1 
ATOM   5985  C  CB  . TRP C 1 193 ? -9.821  -1.330  10.201  1.00 31.01  ? 193 TRP C CB  1 
ATOM   5986  C  CG  . TRP C 1 193 ? -8.729  -2.306  10.500  1.00 28.07  ? 193 TRP C CG  1 
ATOM   5987  C  CD1 . TRP C 1 193 ? -7.793  -2.219  11.480  1.00 28.28  ? 193 TRP C CD1 1 
ATOM   5988  C  CD2 . TRP C 1 193 ? -8.434  -3.506  9.761   1.00 26.53  ? 193 TRP C CD2 1 
ATOM   5989  N  NE1 . TRP C 1 193 ? -6.965  -3.313  11.418  1.00 27.80  ? 193 TRP C NE1 1 
ATOM   5990  C  CE2 . TRP C 1 193 ? -7.325  -4.109  10.373  1.00 26.27  ? 193 TRP C CE2 1 
ATOM   5991  C  CE3 . TRP C 1 193 ? -8.998  -4.109  8.654   1.00 23.89  ? 193 TRP C CE3 1 
ATOM   5992  C  CZ2 . TRP C 1 193 ? -6.742  -5.278  9.909   1.00 26.21  ? 193 TRP C CZ2 1 
ATOM   5993  C  CZ3 . TRP C 1 193 ? -8.423  -5.268  8.201   1.00 26.62  ? 193 TRP C CZ3 1 
ATOM   5994  C  CH2 . TRP C 1 193 ? -7.301  -5.832  8.798   1.00 26.21  ? 193 TRP C CH2 1 
ATOM   5995  N  N   . GLU C 1 194 ? -11.521 -1.371  12.845  1.00 26.14  ? 194 GLU C N   1 
ATOM   5996  C  CA  . GLU C 1 194 ? -11.667 -1.682  14.265  1.00 29.06  ? 194 GLU C CA  1 
ATOM   5997  C  C   . GLU C 1 194 ? -13.012 -2.352  14.551  1.00 33.84  ? 194 GLU C C   1 
ATOM   5998  O  O   . GLU C 1 194 ? -13.228 -2.999  15.579  1.00 38.20  ? 194 GLU C O   1 
ATOM   5999  C  CB  . GLU C 1 194 ? -11.464 -0.450  15.138  1.00 29.84  ? 194 GLU C CB  1 
ATOM   6000  C  CG  . GLU C 1 194 ? -10.140 0.204   14.786  1.00 40.29  ? 194 GLU C CG  1 
ATOM   6001  C  CD  . GLU C 1 194 ? -9.128  0.519   15.860  1.00 45.80  ? 194 GLU C CD  1 
ATOM   6002  O  OE1 . GLU C 1 194 ? -9.264  1.603   16.463  1.00 51.46  ? 194 GLU C OE1 1 
ATOM   6003  O  OE2 . GLU C 1 194 ? -8.183  -0.284  16.018  1.00 50.87  ? 194 GLU C OE2 1 
ATOM   6004  N  N   . GLY C 1 195 ? -13.920 -2.291  13.585  1.00 35.34  ? 195 GLY C N   1 
ATOM   6005  C  CA  . GLY C 1 195 ? -15.200 -2.926  13.770  1.00 33.50  ? 195 GLY C CA  1 
ATOM   6006  C  C   . GLY C 1 195 ? -15.109 -4.420  13.605  1.00 32.43  ? 195 GLY C C   1 
ATOM   6007  O  O   . GLY C 1 195 ? -16.100 -5.079  13.881  1.00 37.43  ? 195 GLY C O   1 
ATOM   6008  N  N   . LEU C 1 196 ? -13.975 -4.923  13.097  1.00 30.93  ? 196 LEU C N   1 
ATOM   6009  C  CA  . LEU C 1 196 ? -13.828 -6.343  12.826  1.00 29.29  ? 196 LEU C CA  1 
ATOM   6010  C  C   . LEU C 1 196 ? -13.282 -6.993  14.069  1.00 25.48  ? 196 LEU C C   1 
ATOM   6011  O  O   . LEU C 1 196 ? -12.565 -6.355  14.823  1.00 30.19  ? 196 LEU C O   1 
ATOM   6012  C  CB  . LEU C 1 196 ? -12.889 -6.651  11.665  1.00 33.37  ? 196 LEU C CB  1 
ATOM   6013  C  CG  . LEU C 1 196 ? -13.479 -6.730  10.259  1.00 30.62  ? 196 LEU C CG  1 
ATOM   6014  C  CD1 . LEU C 1 196 ? -14.291 -5.535  10.005  1.00 33.34  ? 196 LEU C CD1 1 
ATOM   6015  C  CD2 . LEU C 1 196 ? -12.343 -6.779  9.265   1.00 32.46  ? 196 LEU C CD2 1 
ATOM   6016  N  N   . SER C 1 197 ? -13.634 -8.257  14.257  1.00 24.67  ? 197 SER C N   1 
ATOM   6017  C  CA  . SER C 1 197 ? -12.970 -9.063  15.256  1.00 27.28  ? 197 SER C CA  1 
ATOM   6018  C  C   . SER C 1 197 ? -11.525 -9.263  14.786  1.00 32.09  ? 197 SER C C   1 
ATOM   6019  O  O   . SER C 1 197 ? -11.207 -9.100  13.595  1.00 27.60  ? 197 SER C O   1 
ATOM   6020  C  CB  . SER C 1 197 ? -13.627 -10.386 15.428  1.00 26.27  ? 197 SER C CB  1 
ATOM   6021  O  OG  . SER C 1 197 ? -13.379 -11.169 14.265  1.00 24.25  ? 197 SER C OG  1 
ATOM   6022  N  N   . VAL C 1 198 ? -10.663 -9.642  15.736  1.00 31.60  ? 198 VAL C N   1 
ATOM   6023  C  CA  . VAL C 1 198 ? -9.296  -9.947  15.377  1.00 32.25  ? 198 VAL C CA  1 
ATOM   6024  C  C   . VAL C 1 198 ? -9.251  -11.105 14.357  1.00 31.95  ? 198 VAL C C   1 
ATOM   6025  O  O   . VAL C 1 198 ? -8.480  -11.045 13.407  1.00 29.82  ? 198 VAL C O   1 
ATOM   6026  C  CB  . VAL C 1 198 ? -8.465  -10.231 16.634  1.00 31.90  ? 198 VAL C CB  1 
ATOM   6027  C  CG1 . VAL C 1 198 ? -7.097  -10.789 16.222  1.00 35.83  ? 198 VAL C CG1 1 
ATOM   6028  C  CG2 . VAL C 1 198 ? -8.346  -9.023  17.543  1.00 28.87  ? 198 VAL C CG2 1 
ATOM   6029  N  N   . GLU C 1 199 ? -10.084 -12.139 14.526  1.00 31.76  ? 199 GLU C N   1 
ATOM   6030  C  CA  . GLU C 1 199 ? -10.052 -13.315 13.666  1.00 35.69  ? 199 GLU C CA  1 
ATOM   6031  C  C   . GLU C 1 199 ? -10.421 -12.864 12.239  1.00 33.56  ? 199 GLU C C   1 
ATOM   6032  O  O   . GLU C 1 199 ? -9.801  -13.322 11.276  1.00 33.76  ? 199 GLU C O   1 
ATOM   6033  C  CB  . GLU C 1 199 ? -10.895 -14.503 14.183  1.00 42.35  ? 199 GLU C CB  1 
ATOM   6034  C  CG  . GLU C 1 199 ? -10.792 -14.918 15.668  1.00 48.58  ? 199 GLU C CG  1 
ATOM   6035  C  CD  . GLU C 1 199 ? -10.889 -13.937 16.885  1.00 56.24  ? 199 GLU C CD  1 
ATOM   6036  O  OE1 . GLU C 1 199 ? -9.957  -14.165 17.734  1.00 46.60  ? 199 GLU C OE1 1 
ATOM   6037  O  OE2 . GLU C 1 199 ? -11.771 -12.987 17.063  1.00 39.60  ? 199 GLU C OE2 1 
ATOM   6038  N  N   . ALA C 1 200 ? -11.352 -11.907 12.090  1.00 28.06  ? 200 ALA C N   1 
ATOM   6039  C  CA  . ALA C 1 200 ? -11.755 -11.404 10.778  1.00 29.69  ? 200 ALA C CA  1 
ATOM   6040  C  C   . ALA C 1 200 ? -10.619 -10.620 10.104  1.00 31.76  ? 200 ALA C C   1 
ATOM   6041  O  O   . ALA C 1 200 ? -10.433 -10.648 8.876   1.00 30.97  ? 200 ALA C O   1 
ATOM   6042  C  CB  . ALA C 1 200 ? -12.950 -10.493 10.954  1.00 27.91  ? 200 ALA C CB  1 
ATOM   6043  N  N   . GLN C 1 201 ? -9.894  -9.841  10.921  1.00 30.73  ? 201 GLN C N   1 
ATOM   6044  C  CA  . GLN C 1 201 ? -8.769  -9.077  10.421  1.00 26.97  ? 201 GLN C CA  1 
ATOM   6045  C  C   . GLN C 1 201 ? -7.670  -10.012 9.947   1.00 26.33  ? 201 GLN C C   1 
ATOM   6046  O  O   . GLN C 1 201 ? -7.038  -9.754  8.957   1.00 28.29  ? 201 GLN C O   1 
ATOM   6047  C  CB  . GLN C 1 201 ? -8.223  -8.242  11.562  1.00 25.71  ? 201 GLN C CB  1 
ATOM   6048  C  CG  . GLN C 1 201 ? -9.123  -7.066  11.897  1.00 25.57  ? 201 GLN C CG  1 
ATOM   6049  C  CD  . GLN C 1 201 ? -8.527  -6.221  12.989  1.00 24.79  ? 201 GLN C CD  1 
ATOM   6050  O  OE1 . GLN C 1 201 ? -7.542  -6.615  13.611  1.00 30.37  ? 201 GLN C OE1 1 
ATOM   6051  N  NE2 . GLN C 1 201 ? -9.110  -5.066  13.245  1.00 23.68  ? 201 GLN C NE2 1 
ATOM   6052  N  N   . GLU C 1 202 ? -7.443  -11.100 10.678  1.00 26.48  ? 202 GLU C N   1 
ATOM   6053  C  CA  . GLU C 1 202 ? -6.422  -12.062 10.333  1.00 27.53  ? 202 GLU C CA  1 
ATOM   6054  C  C   . GLU C 1 202 ? -6.767  -12.727 9.008   1.00 30.31  ? 202 GLU C C   1 
ATOM   6055  O  O   . GLU C 1 202 ? -5.864  -13.129 8.269   1.00 29.77  ? 202 GLU C O   1 
ATOM   6056  C  CB  . GLU C 1 202 ? -6.253  -13.124 11.423  1.00 29.80  ? 202 GLU C CB  1 
ATOM   6057  C  CG  . GLU C 1 202 ? -5.620  -12.588 12.712  1.00 32.53  ? 202 GLU C CG  1 
ATOM   6058  C  CD  . GLU C 1 202 ? -5.627  -13.568 13.886  1.00 32.80  ? 202 GLU C CD  1 
ATOM   6059  O  OE1 . GLU C 1 202 ? -6.316  -14.600 13.801  1.00 32.74  ? 202 GLU C OE1 1 
ATOM   6060  O  OE2 . GLU C 1 202 ? -4.900  -13.323 14.871  1.00 35.22  ? 202 GLU C OE2 1 
ATOM   6061  N  N   . ARG C 1 203 ? -8.064  -12.898 8.750   1.00 31.22  ? 203 ARG C N   1 
ATOM   6062  C  CA  . ARG C 1 203 ? -8.539  -13.415 7.478   1.00 33.13  ? 203 ARG C CA  1 
ATOM   6063  C  C   . ARG C 1 203 ? -8.259  -12.408 6.350   1.00 32.18  ? 203 ARG C C   1 
ATOM   6064  O  O   . ARG C 1 203 ? -7.932  -12.827 5.217   1.00 30.55  ? 203 ARG C O   1 
ATOM   6065  C  CB  . ARG C 1 203 ? -10.025 -13.790 7.574   1.00 34.70  ? 203 ARG C CB  1 
ATOM   6066  C  CG  . ARG C 1 203 ? -10.317 -15.195 8.083   1.00 36.59  ? 203 ARG C CG  1 
ATOM   6067  C  CD  . ARG C 1 203 ? -11.797 -15.563 7.938   1.00 44.08  ? 203 ARG C CD  1 
ATOM   6068  N  NE  . ARG C 1 203 ? -12.537 -15.350 9.192   1.00 58.52  ? 203 ARG C NE  1 
ATOM   6069  C  CZ  . ARG C 1 203 ? -12.387 -16.078 10.330  1.00 76.66  ? 203 ARG C CZ  1 
ATOM   6070  N  NH1 . ARG C 1 203 ? -12.940 -15.679 11.478  1.00 65.68  ? 203 ARG C NH1 1 
ATOM   6071  N  NH2 . ARG C 1 203 ? -11.624 -17.170 10.345  1.00 87.96  ? 203 ARG C NH2 1 
ATOM   6072  N  N   . VAL C 1 204 ? -8.348  -11.095 6.646   1.00 26.74  ? 204 VAL C N   1 
ATOM   6073  C  CA  . VAL C 1 204 ? -8.009  -10.113 5.621   1.00 26.05  ? 204 VAL C CA  1 
ATOM   6074  C  C   . VAL C 1 204 ? -6.514  -10.184 5.242   1.00 27.71  ? 204 VAL C C   1 
ATOM   6075  O  O   . VAL C 1 204 ? -6.142  -10.085 4.070   1.00 25.80  ? 204 VAL C O   1 
ATOM   6076  C  CB  . VAL C 1 204 ? -8.387  -8.705  6.076   1.00 23.71  ? 204 VAL C CB  1 
ATOM   6077  C  CG1 . VAL C 1 204 ? -7.845  -7.640  5.115   1.00 24.98  ? 204 VAL C CG1 1 
ATOM   6078  C  CG2 . VAL C 1 204 ? -9.877  -8.576  6.316   1.00 24.81  ? 204 VAL C CG2 1 
ATOM   6079  N  N   . ILE C 1 205 ? -5.630  -10.369 6.233   1.00 28.28  ? 205 ILE C N   1 
ATOM   6080  C  CA  . ILE C 1 205 ? -4.206  -10.185 6.020   1.00 27.18  ? 205 ILE C CA  1 
ATOM   6081  C  C   . ILE C 1 205 ? -3.606  -11.520 5.635   1.00 26.51  ? 205 ILE C C   1 
ATOM   6082  O  O   . ILE C 1 205 ? -2.811  -11.597 4.701   1.00 28.15  ? 205 ILE C O   1 
ATOM   6083  C  CB  . ILE C 1 205 ? -3.501  -9.583  7.252   1.00 27.53  ? 205 ILE C CB  1 
ATOM   6084  C  CG1 . ILE C 1 205 ? -4.082  -8.211  7.670   1.00 27.13  ? 205 ILE C CG1 1 
ATOM   6085  C  CG2 . ILE C 1 205 ? -1.988  -9.483  7.014   1.00 29.78  ? 205 ILE C CG2 1 
ATOM   6086  C  CD1 . ILE C 1 205 ? -3.815  -7.110  6.671   1.00 28.08  ? 205 ILE C CD1 1 
ATOM   6087  N  N   . GLY C 1 206 ? -3.971  -12.552 6.380   1.00 28.58  ? 206 GLY C N   1 
ATOM   6088  C  CA  . GLY C 1 206 ? -3.517  -13.899 6.087   1.00 29.85  ? 206 GLY C CA  1 
ATOM   6089  C  C   . GLY C 1 206 ? -2.438  -14.360 7.067   1.00 31.40  ? 206 GLY C C   1 
ATOM   6090  O  O   . GLY C 1 206 ? -1.748  -15.334 6.770   1.00 28.40  ? 206 GLY C O   1 
ATOM   6091  N  N   . ARG C 1 207 ? -2.307  -13.664 8.214   1.00 28.90  ? 207 ARG C N   1 
ATOM   6092  C  CA  . ARG C 1 207 ? -1.406  -14.067 9.274   1.00 28.92  ? 207 ARG C CA  1 
ATOM   6093  C  C   . ARG C 1 207 ? -2.060  -13.699 10.599  1.00 28.34  ? 207 ARG C C   1 
ATOM   6094  O  O   . ARG C 1 207 ? -2.955  -12.859 10.620  1.00 26.13  ? 207 ARG C O   1 
ATOM   6095  C  CB  . ARG C 1 207 ? -0.048  -13.360 9.286   1.00 30.56  ? 207 ARG C CB  1 
ATOM   6096  C  CG  . ARG C 1 207 ? 0.539   -13.118 7.912   1.00 33.07  ? 207 ARG C CG  1 
ATOM   6097  C  CD  . ARG C 1 207 ? 1.791   -12.250 7.982   1.00 34.15  ? 207 ARG C CD  1 
ATOM   6098  N  NE  . ARG C 1 207 ? 2.864   -12.965 8.675   1.00 29.19  ? 207 ARG C NE  1 
ATOM   6099  C  CZ  . ARG C 1 207 ? 3.663   -13.867 8.094   1.00 29.95  ? 207 ARG C CZ  1 
ATOM   6100  N  NH1 . ARG C 1 207 ? 3.649   -14.178 6.787   1.00 24.64  ? 207 ARG C NH1 1 
ATOM   6101  N  NH2 . ARG C 1 207 ? 4.545   -14.455 8.866   1.00 34.94  ? 207 ARG C NH2 1 
ATOM   6102  N  N   . ARG C 1 208 ? -1.534  -14.269 11.694  1.00 27.65  ? 208 ARG C N   1 
ATOM   6103  C  CA  . ARG C 1 208 ? -2.037  -14.017 13.041  1.00 29.86  ? 208 ARG C CA  1 
ATOM   6104  C  C   . ARG C 1 208 ? -1.585  -12.634 13.504  1.00 26.78  ? 208 ARG C C   1 
ATOM   6105  O  O   . ARG C 1 208 ? -0.494  -12.192 13.189  1.00 30.49  ? 208 ARG C O   1 
ATOM   6106  C  CB  . ARG C 1 208 ? -1.558  -15.058 14.069  1.00 34.51  ? 208 ARG C CB  1 
ATOM   6107  C  CG  . ARG C 1 208 ? -1.829  -16.532 13.766  1.00 36.19  ? 208 ARG C CG  1 
ATOM   6108  C  CD  . ARG C 1 208 ? -3.286  -16.854 13.614  1.00 43.97  ? 208 ARG C CD  1 
ATOM   6109  N  NE  . ARG C 1 208 ? -3.977  -16.482 14.856  1.00 63.38  ? 208 ARG C NE  1 
ATOM   6110  C  CZ  . ARG C 1 208 ? -3.788  -17.024 16.071  1.00 74.87  ? 208 ARG C CZ  1 
ATOM   6111  N  NH1 . ARG C 1 208 ? -3.029  -18.107 16.232  1.00 84.38  ? 208 ARG C NH1 1 
ATOM   6112  N  NH2 . ARG C 1 208 ? -4.395  -16.490 17.120  1.00 71.28  ? 208 ARG C NH2 1 
ATOM   6113  N  N   . LYS C 1 209 ? -2.410  -11.959 14.281  1.00 24.07  ? 209 LYS C N   1 
ATOM   6114  C  CA  . LYS C 1 209 ? -2.142  -10.585 14.615  1.00 27.11  ? 209 LYS C CA  1 
ATOM   6115  C  C   . LYS C 1 209 ? -1.076  -10.465 15.701  1.00 29.90  ? 209 LYS C C   1 
ATOM   6116  O  O   . LYS C 1 209 ? -0.085  -9.753  15.486  1.00 31.87  ? 209 LYS C O   1 
ATOM   6117  C  CB  . LYS C 1 209 ? -3.416  -9.880  15.050  1.00 28.64  ? 209 LYS C CB  1 
ATOM   6118  C  CG  . LYS C 1 209 ? -3.240  -8.374  15.184  1.00 27.71  ? 209 LYS C CG  1 
ATOM   6119  C  CD  . LYS C 1 209 ? -4.568  -7.639  15.242  1.00 27.32  ? 209 LYS C CD  1 
ATOM   6120  C  CE  . LYS C 1 209 ? -4.322  -6.199  15.035  1.00 26.74  ? 209 LYS C CE  1 
ATOM   6121  N  NZ  . LYS C 1 209 ? -5.531  -5.462  15.397  1.00 28.09  ? 209 LYS C NZ  1 
ATOM   6122  N  N   . MET C 1 210 ? -1.274  -11.161 16.836  1.00 32.69  ? 210 MET C N   1 
ATOM   6123  C  CA  . MET C 1 210 ? -0.356  -11.041 17.965  1.00 36.61  ? 210 MET C CA  1 
ATOM   6124  C  C   . MET C 1 210 ? 0.953   -11.740 17.604  1.00 35.35  ? 210 MET C C   1 
ATOM   6125  O  O   . MET C 1 210 ? 1.994   -11.114 17.687  1.00 36.41  ? 210 MET C O   1 
ATOM   6126  C  CB  . MET C 1 210 ? -0.908  -11.532 19.323  1.00 40.59  ? 210 MET C CB  1 
ATOM   6127  C  CG  . MET C 1 210 ? -2.135  -10.741 19.897  1.00 49.49  ? 210 MET C CG  1 
ATOM   6128  S  SD  . MET C 1 210 ? -2.240  -8.926  19.762  1.00 62.76  ? 210 MET C SD  1 
ATOM   6129  C  CE  . MET C 1 210 ? -3.981  -8.483  19.618  1.00 51.78  ? 210 MET C CE  1 
ATOM   6130  N  N   . THR C 1 211 ? 0.915   -12.988 17.114  1.00 34.47  ? 211 THR C N   1 
ATOM   6131  C  CA  . THR C 1 211 ? 2.136   -13.787 16.976  1.00 35.33  ? 211 THR C CA  1 
ATOM   6132  C  C   . THR C 1 211 ? 2.796   -13.671 15.596  1.00 35.13  ? 211 THR C C   1 
ATOM   6133  O  O   . THR C 1 211 ? 3.948   -14.083 15.446  1.00 35.78  ? 211 THR C O   1 
ATOM   6134  C  CB  . THR C 1 211 ? 1.839   -15.248 17.308  1.00 34.09  ? 211 THR C CB  1 
ATOM   6135  O  OG1 . THR C 1 211 ? 0.889   -15.751 16.384  1.00 34.82  ? 211 THR C OG1 1 
ATOM   6136  C  CG2 . THR C 1 211 ? 1.153   -15.369 18.651  1.00 37.94  ? 211 THR C CG2 1 
ATOM   6137  N  N   . ASP C 1 212 ? 2.079   -13.164 14.582  1.00 31.20  ? 212 ASP C N   1 
ATOM   6138  C  CA  . ASP C 1 212 ? 2.611   -12.983 13.235  1.00 29.69  ? 212 ASP C CA  1 
ATOM   6139  C  C   . ASP C 1 212 ? 2.990   -14.309 12.568  1.00 27.96  ? 212 ASP C C   1 
ATOM   6140  O  O   . ASP C 1 212 ? 3.712   -14.322 11.572  1.00 27.38  ? 212 ASP C O   1 
ATOM   6141  C  CB  . ASP C 1 212 ? 3.717   -11.952 13.209  1.00 32.96  ? 212 ASP C CB  1 
ATOM   6142  C  CG  . ASP C 1 212 ? 4.160   -11.430 11.848  1.00 31.82  ? 212 ASP C CG  1 
ATOM   6143  O  OD1 . ASP C 1 212 ? 3.269   -11.256 10.918  1.00 29.04  ? 212 ASP C OD1 1 
ATOM   6144  O  OD2 . ASP C 1 212 ? 5.397   -11.093 11.824  1.00 37.28  ? 212 ASP C OD2 1 
ATOM   6145  N  N   . VAL C 1 213 ? 2.397   -15.414 13.040  1.00 26.81  ? 213 VAL C N   1 
ATOM   6146  C  CA  . VAL C 1 213 ? 2.471   -16.687 12.357  1.00 28.80  ? 213 VAL C CA  1 
ATOM   6147  C  C   . VAL C 1 213 ? 1.511   -16.710 11.159  1.00 30.92  ? 213 VAL C C   1 
ATOM   6148  O  O   . VAL C 1 213 ? 0.366   -16.323 11.257  1.00 36.94  ? 213 VAL C O   1 
ATOM   6149  C  CB  . VAL C 1 213 ? 2.196   -17.796 13.384  1.00 28.70  ? 213 VAL C CB  1 
ATOM   6150  C  CG1 . VAL C 1 213 ? 2.167   -19.164 12.736  1.00 29.36  ? 213 VAL C CG1 1 
ATOM   6151  C  CG2 . VAL C 1 213 ? 3.296   -17.819 14.446  1.00 33.78  ? 213 VAL C CG2 1 
ATOM   6152  N  N   . GLU C 1 214 ? 1.961   -17.182 9.999   1.00 32.19  ? 214 GLU C N   1 
ATOM   6153  C  CA  . GLU C 1 214 ? 1.116   -17.269 8.820   1.00 33.95  ? 214 GLU C CA  1 
ATOM   6154  C  C   . GLU C 1 214 ? 0.010   -18.306 9.023   1.00 37.89  ? 214 GLU C C   1 
ATOM   6155  O  O   . GLU C 1 214 ? 0.246   -19.349 9.640   1.00 40.35  ? 214 GLU C O   1 
ATOM   6156  C  CB  . GLU C 1 214 ? 2.052   -17.688 7.689   1.00 35.89  ? 214 GLU C CB  1 
ATOM   6157  C  CG  . GLU C 1 214 ? 1.445   -17.581 6.298   1.00 37.14  ? 214 GLU C CG  1 
ATOM   6158  C  CD  . GLU C 1 214 ? 2.478   -17.779 5.209   1.00 42.24  ? 214 GLU C CD  1 
ATOM   6159  O  OE1 . GLU C 1 214 ? 3.728   -17.846 5.485   1.00 39.19  ? 214 GLU C OE1 1 
ATOM   6160  O  OE2 . GLU C 1 214 ? 1.953   -17.873 4.069   1.00 37.94  ? 214 GLU C OE2 1 
ATOM   6161  N  N   . LEU C 1 215 ? -1.182  -18.020 8.482   1.00 37.00  ? 215 LEU C N   1 
ATOM   6162  C  CA  . LEU C 1 215 ? -2.295  -18.948 8.511   1.00 35.01  ? 215 LEU C CA  1 
ATOM   6163  C  C   . LEU C 1 215 ? -1.975  -20.091 7.567   1.00 40.15  ? 215 LEU C C   1 
ATOM   6164  O  O   . LEU C 1 215 ? -1.408  -19.893 6.497   1.00 39.55  ? 215 LEU C O   1 
ATOM   6165  C  CB  . LEU C 1 215 ? -3.586  -18.283 8.067   1.00 33.62  ? 215 LEU C CB  1 
ATOM   6166  C  CG  . LEU C 1 215 ? -4.161  -17.214 8.995   1.00 35.76  ? 215 LEU C CG  1 
ATOM   6167  C  CD1 . LEU C 1 215 ? -5.500  -16.733 8.479   1.00 36.38  ? 215 LEU C CD1 1 
ATOM   6168  C  CD2 . LEU C 1 215 ? -4.312  -17.709 10.418  1.00 36.96  ? 215 LEU C CD2 1 
ATOM   6169  N  N   . SER C 1 216 ? -2.368  -21.300 7.961   1.00 51.69  ? 216 SER C N   1 
ATOM   6170  C  CA  . SER C 1 216 ? -2.086  -22.473 7.148   1.00 55.26  ? 216 SER C CA  1 
ATOM   6171  C  C   . SER C 1 216 ? -2.887  -22.402 5.847   1.00 58.54  ? 216 SER C C   1 
ATOM   6172  O  O   . SER C 1 216 ? -3.921  -21.719 5.761   1.00 45.73  ? 216 SER C O   1 
ATOM   6173  C  CB  . SER C 1 216 ? -2.399  -23.736 7.922   1.00 55.06  ? 216 SER C CB  1 
ATOM   6174  O  OG  . SER C 1 216 ? -3.773  -23.782 8.294   1.00 59.16  ? 216 SER C OG  1 
ATOM   6175  N  N   . ASP C 1 217 ? -2.437  -23.184 4.859   1.00 58.49  ? 217 ASP C N   1 
ATOM   6176  C  CA  . ASP C 1 217 ? -3.140  -23.292 3.586   1.00 61.03  ? 217 ASP C CA  1 
ATOM   6177  C  C   . ASP C 1 217 ? -4.573  -23.767 3.785   1.00 60.29  ? 217 ASP C C   1 
ATOM   6178  O  O   . ASP C 1 217 ? -5.477  -23.267 3.107   1.00 48.98  ? 217 ASP C O   1 
ATOM   6179  C  CB  . ASP C 1 217 ? -2.309  -24.089 2.603   1.00 60.40  ? 217 ASP C CB  1 
ATOM   6180  C  CG  . ASP C 1 217 ? -0.962  -23.427 2.374   1.00 67.38  ? 217 ASP C CG  1 
ATOM   6181  O  OD1 . ASP C 1 217 ? -0.941  -22.166 2.281   1.00 70.73  ? 217 ASP C OD1 1 
ATOM   6182  O  OD2 . ASP C 1 217 ? 0.046   -24.158 2.360   1.00 70.67  ? 217 ASP C OD2 1 
ATOM   6183  N  N   . ASP C 1 218 ? -4.723  -24.689 4.762   1.00 80.67  ? 218 ASP C N   1 
ATOM   6184  C  CA  . ASP C 1 218 ? -5.977  -25.243 5.270   1.00 79.73  ? 218 ASP C CA  1 
ATOM   6185  C  C   . ASP C 1 218 ? -7.007  -24.121 5.506   1.00 79.32  ? 218 ASP C C   1 
ATOM   6186  O  O   . ASP C 1 218 ? -8.197  -24.404 5.413   1.00 77.09  ? 218 ASP C O   1 
ATOM   6187  C  CB  . ASP C 1 218 ? -5.734  -26.225 6.432   1.00 54.73  ? 218 ASP C CB  1 
ATOM   6188  N  N   . VAL C 1 219 ? -6.591  -22.856 5.764   1.00 71.46  ? 219 VAL C N   1 
ATOM   6189  C  CA  . VAL C 1 219 ? -7.521  -21.852 6.285   1.00 66.07  ? 219 VAL C CA  1 
ATOM   6190  C  C   . VAL C 1 219 ? -7.330  -20.467 5.648   1.00 52.84  ? 219 VAL C C   1 
ATOM   6191  O  O   . VAL C 1 219 ? -8.126  -19.550 5.888   1.00 38.81  ? 219 VAL C O   1 
ATOM   6192  C  CB  . VAL C 1 219 ? -7.431  -21.739 7.829   1.00 71.21  ? 219 VAL C CB  1 
ATOM   6193  C  CG1 . VAL C 1 219 ? -7.130  -23.081 8.501   1.00 71.28  ? 219 VAL C CG1 1 
ATOM   6194  C  CG2 . VAL C 1 219 ? -6.422  -20.684 8.278   1.00 70.79  ? 219 VAL C CG2 1 
ATOM   6195  N  N   . LYS C 1 220 ? -6.249  -20.269 4.888   1.00 46.77  ? 220 LYS C N   1 
ATOM   6196  C  CA  . LYS C 1 220 ? -5.924  -18.928 4.435   1.00 49.12  ? 220 LYS C CA  1 
ATOM   6197  C  C   . LYS C 1 220 ? -6.845  -18.552 3.290   1.00 41.08  ? 220 LYS C C   1 
ATOM   6198  O  O   . LYS C 1 220 ? -6.798  -19.187 2.260   1.00 42.60  ? 220 LYS C O   1 
ATOM   6199  C  CB  . LYS C 1 220 ? -4.474  -18.827 3.956   1.00 51.45  ? 220 LYS C CB  1 
ATOM   6200  C  CG  . LYS C 1 220 ? -3.953  -17.413 3.666   1.00 54.66  ? 220 LYS C CG  1 
ATOM   6201  C  CD  . LYS C 1 220 ? -2.597  -17.388 2.967   1.00 55.12  ? 220 LYS C CD  1 
ATOM   6202  C  CE  . LYS C 1 220 ? -1.732  -18.504 3.421   1.00 55.83  ? 220 LYS C CE  1 
ATOM   6203  N  NZ  . LYS C 1 220 ? -0.325  -18.184 3.250   1.00 54.02  ? 220 LYS C NZ  1 
ATOM   6204  N  N   . PRO C 1 221 ? -7.683  -17.506 3.402   1.00 34.15  ? 221 PRO C N   1 
ATOM   6205  C  CA  . PRO C 1 221 ? -8.530  -17.110 2.289   1.00 33.99  ? 221 PRO C CA  1 
ATOM   6206  C  C   . PRO C 1 221 ? -7.708  -16.778 1.055   1.00 38.78  ? 221 PRO C C   1 
ATOM   6207  O  O   . PRO C 1 221 ? -6.562  -16.334 1.163   1.00 43.05  ? 221 PRO C O   1 
ATOM   6208  C  CB  . PRO C 1 221 ? -9.255  -15.859 2.790   1.00 37.86  ? 221 PRO C CB  1 
ATOM   6209  C  CG  . PRO C 1 221 ? -9.157  -15.940 4.289   1.00 35.48  ? 221 PRO C CG  1 
ATOM   6210  C  CD  . PRO C 1 221 ? -7.877  -16.677 4.596   1.00 36.35  ? 221 PRO C CD  1 
ATOM   6211  N  N   . ALA C 1 222 ? -8.353  -16.930 -0.105  1.00 39.09  ? 222 ALA C N   1 
ATOM   6212  C  CA  . ALA C 1 222 ? -7.744  -16.622 -1.386  1.00 37.14  ? 222 ALA C CA  1 
ATOM   6213  C  C   . ALA C 1 222 ? -7.745  -15.119 -1.635  1.00 36.06  ? 222 ALA C C   1 
ATOM   6214  O  O   . ALA C 1 222 ? -6.972  -14.655 -2.486  1.00 43.69  ? 222 ALA C O   1 
ATOM   6215  C  CB  . ALA C 1 222 ? -8.441  -17.345 -2.522  1.00 41.41  ? 222 ALA C CB  1 
ATOM   6216  N  N   . ASP C 1 223 ? -8.608  -14.358 -0.939  1.00 30.74  ? 223 ASP C N   1 
ATOM   6217  C  CA  . ASP C 1 223 ? -8.582  -12.916 -1.155  1.00 31.64  ? 223 ASP C CA  1 
ATOM   6218  C  C   . ASP C 1 223 ? -7.889  -12.210 0.014   1.00 29.91  ? 223 ASP C C   1 
ATOM   6219  O  O   . ASP C 1 223 ? -7.966  -10.971 0.120   1.00 28.42  ? 223 ASP C O   1 
ATOM   6220  C  CB  . ASP C 1 223 ? -9.947  -12.342 -1.482  1.00 32.92  ? 223 ASP C CB  1 
ATOM   6221  C  CG  . ASP C 1 223 ? -10.968 -12.596 -0.399  1.00 36.07  ? 223 ASP C CG  1 
ATOM   6222  O  OD1 . ASP C 1 223 ? -10.649 -13.458 0.492   1.00 30.17  ? 223 ASP C OD1 1 
ATOM   6223  O  OD2 . ASP C 1 223 ? -12.029 -11.912 -0.479  1.00 44.19  ? 223 ASP C OD2 1 
ATOM   6224  N  N   . SER C 1 224 ? -7.165  -12.997 0.822   1.00 27.45  ? 224 SER C N   1 
ATOM   6225  C  CA  . SER C 1 224 ? -6.258  -12.449 1.819   1.00 31.03  ? 224 SER C CA  1 
ATOM   6226  C  C   . SER C 1 224 ? -5.066  -11.802 1.117   1.00 31.25  ? 224 SER C C   1 
ATOM   6227  O  O   . SER C 1 224 ? -4.663  -12.244 0.037   1.00 31.20  ? 224 SER C O   1 
ATOM   6228  C  CB  . SER C 1 224 ? -5.799  -13.491 2.865   1.00 30.09  ? 224 SER C CB  1 
ATOM   6229  O  OG  . SER C 1 224 ? -4.876  -14.435 2.339   1.00 28.75  ? 224 SER C OG  1 
ATOM   6230  N  N   . HIS C 1 225 ? -4.508  -10.771 1.769   1.00 28.56  ? 225 HIS C N   1 
ATOM   6231  C  CA  . HIS C 1 225 ? -3.427  -9.978  1.218   1.00 28.71  ? 225 HIS C CA  1 
ATOM   6232  C  C   . HIS C 1 225 ? -2.212  -10.858 0.926   1.00 28.18  ? 225 HIS C C   1 
ATOM   6233  O  O   . HIS C 1 225 ? -1.575  -10.752 -0.118  1.00 27.95  ? 225 HIS C O   1 
ATOM   6234  C  CB  . HIS C 1 225 ? -3.090  -8.863  2.204   1.00 32.66  ? 225 HIS C CB  1 
ATOM   6235  C  CG  . HIS C 1 225 ? -1.975  -7.987  1.758   1.00 34.59  ? 225 HIS C CG  1 
ATOM   6236  N  ND1 . HIS C 1 225 ? -2.040  -7.266  0.599   1.00 36.35  ? 225 HIS C ND1 1 
ATOM   6237  C  CD2 . HIS C 1 225 ? -0.801  -7.674  2.321   1.00 37.46  ? 225 HIS C CD2 1 
ATOM   6238  C  CE1 . HIS C 1 225 ? -0.939  -6.543  0.481   1.00 39.34  ? 225 HIS C CE1 1 
ATOM   6239  N  NE2 . HIS C 1 225 ? -0.157  -6.799  1.504   1.00 37.72  ? 225 HIS C NE2 1 
ATOM   6240  N  N   . VAL C 1 226 ? -1.891  -11.732 1.864   1.00 26.83  ? 226 VAL C N   1 
ATOM   6241  C  CA  . VAL C 1 226 ? -0.715  -12.570 1.751   1.00 31.21  ? 226 VAL C CA  1 
ATOM   6242  C  C   . VAL C 1 226 ? -0.895  -13.559 0.619   1.00 30.40  ? 226 VAL C C   1 
ATOM   6243  O  O   . VAL C 1 226 ? 0.090   -13.892 -0.039  1.00 34.99  ? 226 VAL C O   1 
ATOM   6244  C  CB  . VAL C 1 226 ? -0.353  -13.297 3.057   1.00 31.42  ? 226 VAL C CB  1 
ATOM   6245  C  CG1 . VAL C 1 226 ? 0.552   -14.493 2.823   1.00 31.48  ? 226 VAL C CG1 1 
ATOM   6246  C  CG2 . VAL C 1 226 ? 0.332   -12.336 4.004   1.00 33.99  ? 226 VAL C CG2 1 
ATOM   6247  N  N   . ALA C 1 227 ? -2.132  -14.024 0.431   1.00 33.34  ? 227 ALA C N   1 
ATOM   6248  C  CA  . ALA C 1 227 ? -2.471  -14.899 -0.689  1.00 35.38  ? 227 ALA C CA  1 
ATOM   6249  C  C   . ALA C 1 227 ? -2.222  -14.195 -2.028  1.00 31.67  ? 227 ALA C C   1 
ATOM   6250  O  O   . ALA C 1 227 ? -1.516  -14.729 -2.860  1.00 28.27  ? 227 ALA C O   1 
ATOM   6251  C  CB  . ALA C 1 227 ? -3.899  -15.395 -0.568  1.00 33.47  ? 227 ALA C CB  1 
ATOM   6252  N  N   . LEU C 1 228 ? -2.777  -13.001 -2.228  1.00 31.22  ? 228 LEU C N   1 
ATOM   6253  C  CA  . LEU C 1 228 ? -2.691  -12.302 -3.505  1.00 36.80  ? 228 LEU C CA  1 
ATOM   6254  C  C   . LEU C 1 228 ? -1.286  -11.761 -3.815  1.00 38.38  ? 228 LEU C C   1 
ATOM   6255  O  O   . LEU C 1 228 ? -1.001  -11.510 -4.981  1.00 31.58  ? 228 LEU C O   1 
ATOM   6256  C  CB  . LEU C 1 228 ? -3.713  -11.160 -3.546  1.00 37.12  ? 228 LEU C CB  1 
ATOM   6257  C  CG  . LEU C 1 228 ? -5.169  -11.595 -3.650  1.00 38.47  ? 228 LEU C CG  1 
ATOM   6258  C  CD1 . LEU C 1 228 ? -6.066  -10.431 -3.264  1.00 41.46  ? 228 LEU C CD1 1 
ATOM   6259  C  CD2 . LEU C 1 228 ? -5.467  -12.098 -5.064  1.00 35.06  ? 228 LEU C CD2 1 
ATOM   6260  N  N   . THR C 1 229 ? -0.437  -11.498 -2.798  1.00 36.18  ? 229 THR C N   1 
ATOM   6261  C  CA  . THR C 1 229 ? 0.852   -10.894 -3.085  1.00 32.00  ? 229 THR C CA  1 
ATOM   6262  C  C   . THR C 1 229 ? 1.933   -11.959 -3.149  1.00 34.44  ? 229 THR C C   1 
ATOM   6263  O  O   . THR C 1 229 ? 3.067   -11.591 -3.408  1.00 34.61  ? 229 THR C O   1 
ATOM   6264  C  CB  . THR C 1 229 ? 1.180   -9.804  -2.081  1.00 26.40  ? 229 THR C CB  1 
ATOM   6265  O  OG1 . THR C 1 229 ? 1.033   -10.418 -0.805  1.00 22.96  ? 229 THR C OG1 1 
ATOM   6266  C  CG2 . THR C 1 229 ? 0.232   -8.645  -2.278  1.00 25.45  ? 229 THR C CG2 1 
ATOM   6267  N  N   . SER C 1 230 ? 1.569   -13.233 -2.933  1.00 40.87  ? 230 SER C N   1 
ATOM   6268  C  CA  . SER C 1 230 ? 2.445   -14.372 -3.213  1.00 44.41  ? 230 SER C CA  1 
ATOM   6269  C  C   . SER C 1 230 ? 2.312   -14.776 -4.674  1.00 44.76  ? 230 SER C C   1 
ATOM   6270  O  O   . SER C 1 230 ? 1.228   -15.116 -5.122  1.00 52.63  ? 230 SER C O   1 
ATOM   6271  C  CB  . SER C 1 230 ? 2.166   -15.564 -2.330  1.00 41.33  ? 230 SER C CB  1 
ATOM   6272  O  OG  . SER C 1 230 ? 2.338   -15.220 -0.958  1.00 46.86  ? 230 SER C OG  1 
ATOM   6273  N  N   . VAL C 1 231 ? 3.405   -14.683 -5.429  1.00 42.41  ? 231 VAL C N   1 
ATOM   6274  C  CA  . VAL C 1 231 ? 3.394   -15.091 -6.814  1.00 47.13  ? 231 VAL C CA  1 
ATOM   6275  C  C   . VAL C 1 231 ? 4.637   -15.944 -7.066  1.00 52.89  ? 231 VAL C C   1 
ATOM   6276  O  O   . VAL C 1 231 ? 5.722   -15.632 -6.558  1.00 46.74  ? 231 VAL C O   1 
ATOM   6277  C  CB  . VAL C 1 231 ? 3.333   -13.840 -7.709  1.00 52.81  ? 231 VAL C CB  1 
ATOM   6278  C  CG1 . VAL C 1 231 ? 2.254   -12.856 -7.287  1.00 53.16  ? 231 VAL C CG1 1 
ATOM   6279  C  CG2 . VAL C 1 231 ? 4.671   -13.124 -7.767  1.00 61.30  ? 231 VAL C CG2 1 
ATOM   6280  N  N   . THR C 1 232 ? 4.466   -17.041 -7.821  1.00 61.14  ? 232 THR C N   1 
ATOM   6281  C  CA  . THR C 1 232 ? 5.610   -17.823 -8.268  1.00 66.85  ? 232 THR C CA  1 
ATOM   6282  C  C   . THR C 1 232 ? 5.811   -17.534 -9.747  1.00 58.48  ? 232 THR C C   1 
ATOM   6283  O  O   . THR C 1 232 ? 4.848   -17.294 -10.457 1.00 55.20  ? 232 THR C O   1 
ATOM   6284  C  CB  . THR C 1 232 ? 5.417   -19.307 -7.974  1.00 64.23  ? 232 THR C CB  1 
ATOM   6285  O  OG1 . THR C 1 232 ? 4.128   -19.434 -8.538  1.00 59.20  ? 232 THR C OG1 1 
ATOM   6286  C  CG2 . THR C 1 232 ? 5.405   -19.655 -6.496  1.00 59.08  ? 232 THR C CG2 1 
ATOM   6287  N  N   . GLY C 1 233 ? 7.072   -17.446 -10.159 1.00 72.74  ? 233 GLY C N   1 
ATOM   6288  C  CA  . GLY C 1 233 ? 7.385   -17.061 -11.516 1.00 81.78  ? 233 GLY C CA  1 
ATOM   6289  C  C   . GLY C 1 233 ? 7.061   -18.230 -12.429 1.00 101.88 ? 233 GLY C C   1 
ATOM   6290  O  O   . GLY C 1 233 ? 6.814   -19.343 -11.935 1.00 82.88  ? 233 GLY C O   1 
ATOM   6291  N  N   . PRO C 1 234 ? 7.034   -17.992 -13.765 1.00 122.40 ? 234 PRO C N   1 
ATOM   6292  C  CA  . PRO C 1 234 ? 7.363   -19.062 -14.714 1.00 110.86 ? 234 PRO C CA  1 
ATOM   6293  C  C   . PRO C 1 234 ? 8.451   -20.041 -14.215 1.00 90.02  ? 234 PRO C C   1 
ATOM   6294  O  O   . PRO C 1 234 ? 8.237   -21.248 -14.308 1.00 68.62  ? 234 PRO C O   1 
ATOM   6295  C  CB  . PRO C 1 234 ? 7.756   -18.221 -15.979 1.00 104.24 ? 234 PRO C CB  1 
ATOM   6296  C  CG  . PRO C 1 234 ? 6.891   -16.945 -15.911 1.00 89.00  ? 234 PRO C CG  1 
ATOM   6297  C  CD  . PRO C 1 234 ? 6.674   -16.705 -14.416 1.00 97.26  ? 234 PRO C CD  1 
ATOM   6298  N  N   . ASP C 1 235 ? 9.538   -19.524 -13.582 1.00 91.09  ? 235 ASP C N   1 
ATOM   6299  C  CA  . ASP C 1 235 ? 10.689  -20.291 -13.080 1.00 77.63  ? 235 ASP C CA  1 
ATOM   6300  C  C   . ASP C 1 235 ? 10.280  -21.353 -12.042 1.00 82.67  ? 235 ASP C C   1 
ATOM   6301  O  O   . ASP C 1 235 ? 11.029  -22.308 -11.887 1.00 63.36  ? 235 ASP C O   1 
ATOM   6302  C  CB  . ASP C 1 235 ? 11.898  -19.402 -12.708 1.00 71.02  ? 235 ASP C CB  1 
ATOM   6303  C  CG  . ASP C 1 235 ? 12.061  -18.850 -11.286 1.00 55.16  ? 235 ASP C CG  1 
ATOM   6304  N  N   . GLY C 1 236 ? 9.122   -21.232 -11.347 1.00 94.36  ? 236 GLY C N   1 
ATOM   6305  C  CA  . GLY C 1 236 ? 8.736   -22.144 -10.268 1.00 81.70  ? 236 GLY C CA  1 
ATOM   6306  C  C   . GLY C 1 236 ? 9.116   -21.577 -8.895  1.00 94.20  ? 236 GLY C C   1 
ATOM   6307  O  O   . GLY C 1 236 ? 8.461   -21.876 -7.897  1.00 74.72  ? 236 GLY C O   1 
ATOM   6308  N  N   . SER C 1 237 ? 10.193  -20.758 -8.877  1.00 105.89 ? 237 SER C N   1 
ATOM   6309  C  CA  . SER C 1 237 ? 10.634  -19.946 -7.746  1.00 82.19  ? 237 SER C CA  1 
ATOM   6310  C  C   . SER C 1 237 ? 9.652   -18.796 -7.514  1.00 80.10  ? 237 SER C C   1 
ATOM   6311  O  O   . SER C 1 237 ? 9.098   -18.251 -8.478  1.00 74.58  ? 237 SER C O   1 
ATOM   6312  C  CB  . SER C 1 237 ? 12.040  -19.402 -7.981  1.00 60.20  ? 237 SER C CB  1 
ATOM   6313  N  N   . ASP C 1 238 ? 9.445   -18.456 -6.228  1.00 73.08  ? 238 ASP C N   1 
ATOM   6314  C  CA  . ASP C 1 238 ? 8.718   -17.265 -5.799  1.00 67.75  ? 238 ASP C CA  1 
ATOM   6315  C  C   . ASP C 1 238 ? 9.331   -15.980 -6.358  1.00 57.79  ? 238 ASP C C   1 
ATOM   6316  O  O   . ASP C 1 238 ? 10.550  -15.873 -6.483  1.00 61.07  ? 238 ASP C O   1 
ATOM   6317  C  CB  . ASP C 1 238 ? 8.763   -17.097 -4.290  1.00 68.12  ? 238 ASP C CB  1 
ATOM   6318  C  CG  . ASP C 1 238 ? 7.880   -18.073 -3.547  1.00 67.08  ? 238 ASP C CG  1 
ATOM   6319  O  OD1 . ASP C 1 238 ? 6.712   -18.231 -3.983  1.00 63.52  ? 238 ASP C OD1 1 
ATOM   6320  O  OD2 . ASP C 1 238 ? 8.377   -18.628 -2.552  1.00 64.70  ? 238 ASP C OD2 1 
ATOM   6321  N  N   . LEU C 1 239 ? 8.469   -14.988 -6.624  1.00 44.79  ? 239 LEU C N   1 
ATOM   6322  C  CA  . LEU C 1 239 ? 8.905   -13.628 -6.945  1.00 44.37  ? 239 LEU C CA  1 
ATOM   6323  C  C   . LEU C 1 239 ? 8.765   -12.699 -5.735  1.00 40.12  ? 239 LEU C C   1 
ATOM   6324  O  O   . LEU C 1 239 ? 7.672   -12.491 -5.222  1.00 37.49  ? 239 LEU C O   1 
ATOM   6325  C  CB  . LEU C 1 239 ? 8.100   -13.065 -8.102  1.00 46.23  ? 239 LEU C CB  1 
ATOM   6326  C  CG  . LEU C 1 239 ? 8.188   -13.836 -9.413  1.00 51.88  ? 239 LEU C CG  1 
ATOM   6327  C  CD1 . LEU C 1 239 ? 7.130   -13.244 -10.329 1.00 49.88  ? 239 LEU C CD1 1 
ATOM   6328  C  CD2 . LEU C 1 239 ? 9.629   -13.777 -9.964  1.00 52.69  ? 239 LEU C CD2 1 
ATOM   6329  N  N   . GLU C 1 240 ? 9.880   -12.085 -5.319  1.00 39.65  ? 240 GLU C N   1 
ATOM   6330  C  CA  . GLU C 1 240 ? 9.931   -11.302 -4.096  1.00 39.98  ? 240 GLU C CA  1 
ATOM   6331  C  C   . GLU C 1 240 ? 10.240  -9.842  -4.436  1.00 32.26  ? 240 GLU C C   1 
ATOM   6332  O  O   . GLU C 1 240 ? 10.930  -9.579  -5.416  1.00 30.77  ? 240 GLU C O   1 
ATOM   6333  C  CB  . GLU C 1 240 ? 10.974  -11.906 -3.149  1.00 45.17  ? 240 GLU C CB  1 
ATOM   6334  C  CG  . GLU C 1 240 ? 10.855  -13.408 -2.882  1.00 48.53  ? 240 GLU C CG  1 
ATOM   6335  C  CD  . GLU C 1 240 ? 11.727  -13.999 -1.771  1.00 50.44  ? 240 GLU C CD  1 
ATOM   6336  O  OE1 . GLU C 1 240 ? 12.944  -14.001 -1.993  1.00 48.45  ? 240 GLU C OE1 1 
ATOM   6337  O  OE2 . GLU C 1 240 ? 11.232  -14.501 -0.728  1.00 60.73  ? 240 GLU C OE2 1 
ATOM   6338  N  N   . ILE C 1 241 ? 9.715   -8.919  -3.620  1.00 28.39  ? 241 ILE C N   1 
ATOM   6339  C  CA  . ILE C 1 241 ? 10.147  -7.529  -3.619  1.00 28.75  ? 241 ILE C CA  1 
ATOM   6340  C  C   . ILE C 1 241 ? 10.685  -7.181  -2.244  1.00 26.63  ? 241 ILE C C   1 
ATOM   6341  O  O   . ILE C 1 241 ? 10.582  -7.979  -1.327  1.00 28.30  ? 241 ILE C O   1 
ATOM   6342  C  CB  . ILE C 1 241 ? 9.025   -6.566  -4.036  1.00 29.37  ? 241 ILE C CB  1 
ATOM   6343  C  CG1 . ILE C 1 241 ? 7.924   -6.549  -3.020  1.00 32.21  ? 241 ILE C CG1 1 
ATOM   6344  C  CG2 . ILE C 1 241 ? 8.518   -6.899  -5.440  1.00 30.27  ? 241 ILE C CG2 1 
ATOM   6345  C  CD1 . ILE C 1 241 ? 6.801   -5.579  -3.329  1.00 31.39  ? 241 ILE C CD1 1 
ATOM   6346  N  N   . LEU C 1 242 ? 11.271  -5.991  -2.129  1.00 25.31  ? 242 LEU C N   1 
ATOM   6347  C  CA  . LEU C 1 242 ? 11.693  -5.462  -0.849  1.00 22.80  ? 242 LEU C CA  1 
ATOM   6348  C  C   . LEU C 1 242 ? 10.868  -4.245  -0.501  1.00 20.83  ? 242 LEU C C   1 
ATOM   6349  O  O   . LEU C 1 242 ? 10.942  -3.253  -1.183  1.00 18.80  ? 242 LEU C O   1 
ATOM   6350  C  CB  . LEU C 1 242 ? 13.150  -5.055  -0.972  1.00 26.71  ? 242 LEU C CB  1 
ATOM   6351  C  CG  . LEU C 1 242 ? 13.808  -4.559  0.309   1.00 27.97  ? 242 LEU C CG  1 
ATOM   6352  C  CD1 . LEU C 1 242 ? 13.821  -5.648  1.344   1.00 29.34  ? 242 LEU C CD1 1 
ATOM   6353  C  CD2 . LEU C 1 242 ? 15.198  -4.062  0.014   1.00 28.33  ? 242 LEU C CD2 1 
ATOM   6354  N  N   . ARG C 1 243 ? 10.151  -4.325  0.598   1.00 21.67  ? 243 ARG C N   1 
ATOM   6355  C  CA  . ARG C 1 243 ? 9.252   -3.266  1.007   1.00 24.05  ? 243 ARG C CA  1 
ATOM   6356  C  C   . ARG C 1 243 ? 9.783   -2.594  2.268   1.00 23.18  ? 243 ARG C C   1 
ATOM   6357  O  O   . ARG C 1 243 ? 10.456  -3.267  3.034   1.00 23.21  ? 243 ARG C O   1 
ATOM   6358  C  CB  . ARG C 1 243 ? 7.902   -3.868  1.408   1.00 27.53  ? 243 ARG C CB  1 
ATOM   6359  C  CG  . ARG C 1 243 ? 7.124   -4.474  0.260   1.00 29.67  ? 243 ARG C CG  1 
ATOM   6360  C  CD  . ARG C 1 243 ? 5.984   -5.302  0.809   1.00 33.34  ? 243 ARG C CD  1 
ATOM   6361  N  NE  . ARG C 1 243 ? 6.515   -6.542  1.398   1.00 34.90  ? 243 ARG C NE  1 
ATOM   6362  C  CZ  . ARG C 1 243 ? 6.294   -6.975  2.628   1.00 35.33  ? 243 ARG C CZ  1 
ATOM   6363  N  NH1 . ARG C 1 243 ? 5.488   -6.314  3.432   1.00 32.13  ? 243 ARG C NH1 1 
ATOM   6364  N  NH2 . ARG C 1 243 ? 6.857   -8.100  3.034   1.00 43.69  ? 243 ARG C NH2 1 
ATOM   6365  N  N   . ASP C 1 244 ? 9.507   -1.282  2.458   1.00 22.79  ? 244 ASP C N   1 
ATOM   6366  C  CA  . ASP C 1 244 ? 9.788   -0.595  3.710   1.00 24.86  ? 244 ASP C CA  1 
ATOM   6367  C  C   . ASP C 1 244 ? 8.663   0.386   3.995   1.00 25.76  ? 244 ASP C C   1 
ATOM   6368  O  O   . ASP C 1 244 ? 8.859   1.592   4.066   1.00 29.49  ? 244 ASP C O   1 
ATOM   6369  C  CB  . ASP C 1 244 ? 11.167  0.035   3.705   1.00 28.72  ? 244 ASP C CB  1 
ATOM   6370  C  CG  . ASP C 1 244 ? 11.809  0.348   5.056   1.00 35.88  ? 244 ASP C CG  1 
ATOM   6371  O  OD1 . ASP C 1 244 ? 11.337  -0.211  6.129   1.00 30.91  ? 244 ASP C OD1 1 
ATOM   6372  O  OD2 . ASP C 1 244 ? 12.739  1.216   5.024   1.00 39.23  ? 244 ASP C OD2 1 
ATOM   6373  N  N   . ASN C 1 245 ? 7.476   -0.180  4.180   1.00 26.33  ? 245 ASN C N   1 
ATOM   6374  C  CA  . ASN C 1 245 ? 6.254   0.544   4.487   1.00 26.94  ? 245 ASN C CA  1 
ATOM   6375  C  C   . ASN C 1 245 ? 6.399   1.292   5.812   1.00 24.35  ? 245 ASN C C   1 
ATOM   6376  O  O   . ASN C 1 245 ? 6.924   0.763   6.779   1.00 27.22  ? 245 ASN C O   1 
ATOM   6377  C  CB  . ASN C 1 245 ? 5.068   -0.410  4.571   1.00 28.27  ? 245 ASN C CB  1 
ATOM   6378  C  CG  . ASN C 1 245 ? 4.865   -1.252  3.325   1.00 34.65  ? 245 ASN C CG  1 
ATOM   6379  O  OD1 . ASN C 1 245 ? 5.513   -1.037  2.292   1.00 35.11  ? 245 ASN C OD1 1 
ATOM   6380  N  ND2 . ASN C 1 245 ? 3.957   -2.218  3.401   1.00 41.44  ? 245 ASN C ND2 1 
ATOM   6381  N  N   . MET C 1 246 ? 5.945   2.534   5.829   1.00 21.92  ? 246 MET C N   1 
ATOM   6382  C  CA  . MET C 1 246 ? 6.049   3.403   6.986   1.00 22.61  ? 246 MET C CA  1 
ATOM   6383  C  C   . MET C 1 246 ? 4.658   3.952   7.325   1.00 22.96  ? 246 MET C C   1 
ATOM   6384  O  O   . MET C 1 246 ? 3.977   4.555   6.482   1.00 20.76  ? 246 MET C O   1 
ATOM   6385  C  CB  . MET C 1 246 ? 7.008   4.582   6.737   1.00 24.57  ? 246 MET C CB  1 
ATOM   6386  C  CG  . MET C 1 246 ? 8.489   4.192   6.645   1.00 25.77  ? 246 MET C CG  1 
ATOM   6387  S  SD  . MET C 1 246 ? 9.110   3.365   8.133   1.00 26.24  ? 246 MET C SD  1 
ATOM   6388  C  CE  . MET C 1 246 ? 9.381   4.919   9.026   1.00 25.23  ? 246 MET C CE  1 
ATOM   6389  N  N   . PRO C 1 247 ? 4.232   3.804   8.599   1.00 21.12  ? 247 PRO C N   1 
ATOM   6390  C  CA  . PRO C 1 247 ? 3.073   4.512   9.121   1.00 20.77  ? 247 PRO C CA  1 
ATOM   6391  C  C   . PRO C 1 247 ? 3.302   6.007   9.100   1.00 19.36  ? 247 PRO C C   1 
ATOM   6392  O  O   . PRO C 1 247 ? 4.414   6.483   9.269   1.00 20.07  ? 247 PRO C O   1 
ATOM   6393  C  CB  . PRO C 1 247 ? 2.949   4.029   10.560  1.00 24.64  ? 247 PRO C CB  1 
ATOM   6394  C  CG  . PRO C 1 247 ? 3.809   2.750   10.652  1.00 25.01  ? 247 PRO C CG  1 
ATOM   6395  C  CD  . PRO C 1 247 ? 4.854   2.912   9.589   1.00 24.13  ? 247 PRO C CD  1 
ATOM   6396  N  N   . PHE C 1 248 ? 2.218   6.745   8.935   1.00 20.01  ? 248 PHE C N   1 
ATOM   6397  C  CA  . PHE C 1 248 ? 2.273   8.196   9.041   1.00 21.56  ? 248 PHE C CA  1 
ATOM   6398  C  C   . PHE C 1 248 ? 0.868   8.621   9.437   1.00 21.51  ? 248 PHE C C   1 
ATOM   6399  O  O   . PHE C 1 248 ? -0.077  7.851   9.292   1.00 23.11  ? 248 PHE C O   1 
ATOM   6400  C  CB  . PHE C 1 248 ? 2.751   8.854   7.739   1.00 20.78  ? 248 PHE C CB  1 
ATOM   6401  C  CG  . PHE C 1 248 ? 1.718   8.768   6.646   1.00 20.62  ? 248 PHE C CG  1 
ATOM   6402  C  CD1 . PHE C 1 248 ? 0.716   9.725   6.548   1.00 19.14  ? 248 PHE C CD1 1 
ATOM   6403  C  CD2 . PHE C 1 248 ? 1.721   7.697   5.762   1.00 23.03  ? 248 PHE C CD2 1 
ATOM   6404  C  CE1 . PHE C 1 248 ? -0.280  9.635   5.586   1.00 20.08  ? 248 PHE C CE1 1 
ATOM   6405  C  CE2 . PHE C 1 248 ? 0.730   7.608   4.781   1.00 25.10  ? 248 PHE C CE2 1 
ATOM   6406  C  CZ  . PHE C 1 248 ? -0.285  8.581   4.697   1.00 22.97  ? 248 PHE C CZ  1 
ATOM   6407  N  N   . GLY C 1 249 ? 0.693   9.851   9.911   1.00 24.29  ? 249 GLY C N   1 
ATOM   6408  C  CA  . GLY C 1 249 ? -0.669  10.324  10.026  1.00 24.29  ? 249 GLY C CA  1 
ATOM   6409  C  C   . GLY C 1 249 ? -0.804  11.587  10.841  1.00 26.74  ? 249 GLY C C   1 
ATOM   6410  O  O   . GLY C 1 249 ? 0.172   12.139  11.289  1.00 26.95  ? 249 GLY C O   1 
ATOM   6411  N  N   . SER C 1 250 ? -2.052  11.965  11.088  1.00 29.24  ? 250 SER C N   1 
ATOM   6412  C  CA  . SER C 1 250 ? -2.388  13.172  11.831  1.00 27.70  ? 250 SER C CA  1 
ATOM   6413  C  C   . SER C 1 250 ? -3.684  12.925  12.599  1.00 25.62  ? 250 SER C C   1 
ATOM   6414  O  O   . SER C 1 250 ? -4.658  12.470  11.996  1.00 24.29  ? 250 SER C O   1 
ATOM   6415  C  CB  . SER C 1 250 ? -2.473  14.324  10.858  1.00 26.35  ? 250 SER C CB  1 
ATOM   6416  O  OG  . SER C 1 250 ? -3.424  15.247  11.319  1.00 26.81  ? 250 SER C OG  1 
ATOM   6417  N  N   . VAL C 1 251 ? -3.685  13.112  13.930  1.00 29.88  ? 251 VAL C N   1 
ATOM   6418  C  CA  . VAL C 1 251 ? -4.850  12.640  14.691  1.00 33.41  ? 251 VAL C CA  1 
ATOM   6419  C  C   . VAL C 1 251 ? -5.998  13.629  14.540  1.00 30.92  ? 251 VAL C C   1 
ATOM   6420  O  O   . VAL C 1 251 ? -7.141  13.247  14.425  1.00 34.83  ? 251 VAL C O   1 
ATOM   6421  C  CB  . VAL C 1 251 ? -4.651  12.320  16.175  1.00 34.36  ? 251 VAL C CB  1 
ATOM   6422  C  CG1 . VAL C 1 251 ? -3.681  11.162  16.400  1.00 41.45  ? 251 VAL C CG1 1 
ATOM   6423  C  CG2 . VAL C 1 251 ? -4.172  13.551  16.878  1.00 39.70  ? 251 VAL C CG2 1 
ATOM   6424  N  N   . GLY C 1 252 ? -5.673  14.904  14.531  1.00 29.24  ? 252 GLY C N   1 
ATOM   6425  C  CA  . GLY C 1 252 ? -6.653  15.946  14.324  1.00 30.83  ? 252 GLY C CA  1 
ATOM   6426  C  C   . GLY C 1 252 ? -7.377  15.801  12.995  1.00 32.31  ? 252 GLY C C   1 
ATOM   6427  O  O   . GLY C 1 252 ? -8.533  16.100  12.940  1.00 32.51  ? 252 GLY C O   1 
ATOM   6428  N  N   . ARG C 1 253 ? -6.713  15.380  11.916  1.00 37.58  ? 253 ARG C N   1 
ATOM   6429  C  CA  . ARG C 1 253 ? -7.336  15.302  10.599  1.00 34.61  ? 253 ARG C CA  1 
ATOM   6430  C  C   . ARG C 1 253 ? -7.911  13.902  10.387  1.00 36.68  ? 253 ARG C C   1 
ATOM   6431  O  O   . ARG C 1 253 ? -8.385  13.586  9.319   1.00 40.16  ? 253 ARG C O   1 
ATOM   6432  C  CB  . ARG C 1 253 ? -6.352  15.612  9.458   1.00 30.66  ? 253 ARG C CB  1 
ATOM   6433  C  CG  . ARG C 1 253 ? -5.882  17.052  9.570   1.00 37.92  ? 253 ARG C CG  1 
ATOM   6434  C  CD  . ARG C 1 253 ? -5.243  17.665  8.303   1.00 43.20  ? 253 ARG C CD  1 
ATOM   6435  N  NE  . ARG C 1 253 ? -4.239  16.774  7.717   1.00 51.28  ? 253 ARG C NE  1 
ATOM   6436  N  N   . GLU C 1 254 ? -7.840  13.040  11.385  1.00 34.92  ? 254 GLU C N   1 
ATOM   6437  C  CA  . GLU C 1 254 ? -8.150  11.633  11.199  1.00 38.61  ? 254 GLU C CA  1 
ATOM   6438  C  C   . GLU C 1 254 ? -7.484  11.000  9.980   1.00 33.01  ? 254 GLU C C   1 
ATOM   6439  O  O   . GLU C 1 254 ? -8.102  10.149  9.369   1.00 36.68  ? 254 GLU C O   1 
ATOM   6440  C  CB  . GLU C 1 254 ? -9.652  11.433  11.057  1.00 46.23  ? 254 GLU C CB  1 
ATOM   6441  C  CG  . GLU C 1 254 ? -10.456 11.897  12.269  1.00 56.50  ? 254 GLU C CG  1 
ATOM   6442  C  CD  . GLU C 1 254 ? -11.924 11.512  12.155  1.00 60.34  ? 254 GLU C CD  1 
ATOM   6443  O  OE1 . GLU C 1 254 ? -12.231 10.298  12.262  1.00 56.55  ? 254 GLU C OE1 1 
ATOM   6444  O  OE2 . GLU C 1 254 ? -12.744 12.423  11.900  1.00 68.82  ? 254 GLU C OE2 1 
ATOM   6445  N  N   . GLU C 1 255 ? -6.213  11.298  9.686   1.00 30.02  ? 255 GLU C N   1 
ATOM   6446  C  CA  . GLU C 1 255 ? -5.465  10.538  8.695   1.00 31.43  ? 255 GLU C CA  1 
ATOM   6447  C  C   . GLU C 1 255 ? -4.589  9.486   9.345   1.00 30.53  ? 255 GLU C C   1 
ATOM   6448  O  O   . GLU C 1 255 ? -3.705  9.802   10.127  1.00 33.42  ? 255 GLU C O   1 
ATOM   6449  C  CB  . GLU C 1 255 ? -4.505  11.416  7.912   1.00 43.66  ? 255 GLU C CB  1 
ATOM   6450  C  CG  . GLU C 1 255 ? -5.272  12.432  7.069   1.00 52.85  ? 255 GLU C CG  1 
ATOM   6451  C  CD  . GLU C 1 255 ? -4.304  13.406  6.450   1.00 59.42  ? 255 GLU C CD  1 
ATOM   6452  O  OE1 . GLU C 1 255 ? -3.100  13.034  6.347   1.00 55.18  ? 255 GLU C OE1 1 
ATOM   6453  O  OE2 . GLU C 1 255 ? -4.753  14.544  6.175   1.00 59.70  ? 255 GLU C OE2 1 
ATOM   6454  N  N   . PHE C 1 256 ? -4.842  8.232   9.026   1.00 27.86  ? 256 PHE C N   1 
ATOM   6455  C  CA  . PHE C 1 256 ? -3.991  7.143   9.465   1.00 30.44  ? 256 PHE C CA  1 
ATOM   6456  C  C   . PHE C 1 256 ? -3.530  6.402   8.201   1.00 27.90  ? 256 PHE C C   1 
ATOM   6457  O  O   . PHE C 1 256 ? -4.336  5.942   7.406   1.00 30.25  ? 256 PHE C O   1 
ATOM   6458  C  CB  . PHE C 1 256 ? -4.737  6.254   10.488  1.00 32.26  ? 256 PHE C CB  1 
ATOM   6459  C  CG  . PHE C 1 256 ? -5.351  7.025   11.644  1.00 33.42  ? 256 PHE C CG  1 
ATOM   6460  C  CD1 . PHE C 1 256 ? -4.607  7.324   12.778  1.00 39.63  ? 256 PHE C CD1 1 
ATOM   6461  C  CD2 . PHE C 1 256 ? -6.657  7.497   11.587  1.00 34.48  ? 256 PHE C CD2 1 
ATOM   6462  C  CE1 . PHE C 1 256 ? -5.138  8.105   13.795  1.00 36.62  ? 256 PHE C CE1 1 
ATOM   6463  C  CE2 . PHE C 1 256 ? -7.190  8.235   12.629  1.00 32.88  ? 256 PHE C CE2 1 
ATOM   6464  C  CZ  . PHE C 1 256 ? -6.409  8.583   13.699  1.00 34.45  ? 256 PHE C CZ  1 
ATOM   6465  N  N   . GLY C 1 257 ? -2.230  6.310   7.989   1.00 24.35  ? 257 GLY C N   1 
ATOM   6466  C  CA  . GLY C 1 257 ? -1.729  5.948   6.679   1.00 23.88  ? 257 GLY C CA  1 
ATOM   6467  C  C   . GLY C 1 257 ? -0.642  4.870   6.732   1.00 23.56  ? 257 GLY C C   1 
ATOM   6468  O  O   . GLY C 1 257 ? -0.028  4.594   7.784   1.00 26.30  ? 257 GLY C O   1 
ATOM   6469  N  N   . THR C 1 258 ? -0.456  4.252   5.564   1.00 20.77  ? 258 THR C N   1 
ATOM   6470  C  CA  . THR C 1 258 ? 0.685   3.414   5.291   1.00 21.60  ? 258 THR C CA  1 
ATOM   6471  C  C   . THR C 1 258 ? 1.310   3.959   4.025   1.00 23.08  ? 258 THR C C   1 
ATOM   6472  O  O   . THR C 1 258 ? 0.598   4.100   3.045   1.00 26.08  ? 258 THR C O   1 
ATOM   6473  C  CB  . THR C 1 258 ? 0.240   1.971   5.102   1.00 24.08  ? 258 THR C CB  1 
ATOM   6474  O  OG1 . THR C 1 258 ? -0.137  1.506   6.391   1.00 27.96  ? 258 THR C OG1 1 
ATOM   6475  C  CG2 . THR C 1 258 ? 1.365   1.124   4.548   1.00 25.68  ? 258 THR C CG2 1 
ATOM   6476  N  N   . TYR C 1 259 ? 2.590   4.340   4.096   1.00 22.77  ? 259 TYR C N   1 
ATOM   6477  C  CA  . TYR C 1 259 ? 3.335   4.749   2.918   1.00 21.54  ? 259 TYR C CA  1 
ATOM   6478  C  C   . TYR C 1 259 ? 4.005   3.479   2.376   1.00 20.48  ? 259 TYR C C   1 
ATOM   6479  O  O   . TYR C 1 259 ? 4.936   2.950   2.963   1.00 17.90  ? 259 TYR C O   1 
ATOM   6480  C  CB  . TYR C 1 259 ? 4.297   5.915   3.190   1.00 21.13  ? 259 TYR C CB  1 
ATOM   6481  C  CG  . TYR C 1 259 ? 4.701   6.662   1.927   1.00 23.02  ? 259 TYR C CG  1 
ATOM   6482  C  CD1 . TYR C 1 259 ? 5.612   6.132   1.022   1.00 24.35  ? 259 TYR C CD1 1 
ATOM   6483  C  CD2 . TYR C 1 259 ? 4.105   7.862   1.587   1.00 23.96  ? 259 TYR C CD2 1 
ATOM   6484  C  CE1 . TYR C 1 259 ? 5.942   6.810   -0.139  1.00 25.68  ? 259 TYR C CE1 1 
ATOM   6485  C  CE2 . TYR C 1 259 ? 4.425   8.540   0.426   1.00 23.33  ? 259 TYR C CE2 1 
ATOM   6486  C  CZ  . TYR C 1 259 ? 5.338   8.016   -0.457  1.00 26.93  ? 259 TYR C CZ  1 
ATOM   6487  O  OH  . TYR C 1 259 ? 5.662   8.715   -1.621  1.00 30.84  ? 259 TYR C OH  1 
ATOM   6488  N  N   . PHE C 1 260 ? 3.496   2.961   1.254   1.00 19.88  ? 260 PHE C N   1 
ATOM   6489  C  CA  . PHE C 1 260 ? 4.081   1.799   0.629   1.00 18.81  ? 260 PHE C CA  1 
ATOM   6490  C  C   . PHE C 1 260 ? 5.214   2.223   -0.266  1.00 19.12  ? 260 PHE C C   1 
ATOM   6491  O  O   . PHE C 1 260 ? 5.081   3.130   -1.082  1.00 23.87  ? 260 PHE C O   1 
ATOM   6492  C  CB  . PHE C 1 260 ? 3.015   1.109   -0.207  1.00 21.10  ? 260 PHE C CB  1 
ATOM   6493  C  CG  . PHE C 1 260 ? 3.583   -0.039  -1.015  1.00 21.88  ? 260 PHE C CG  1 
ATOM   6494  C  CD1 . PHE C 1 260 ? 3.782   -1.281  -0.433  1.00 22.32  ? 260 PHE C CD1 1 
ATOM   6495  C  CD2 . PHE C 1 260 ? 3.899   0.136   -2.355  1.00 24.45  ? 260 PHE C CD2 1 
ATOM   6496  C  CE1 . PHE C 1 260 ? 4.345   -2.312  -1.159  1.00 22.15  ? 260 PHE C CE1 1 
ATOM   6497  C  CE2 . PHE C 1 260 ? 4.460   -0.897  -3.085  1.00 24.67  ? 260 PHE C CE2 1 
ATOM   6498  C  CZ  . PHE C 1 260 ? 4.696   -2.114  -2.482  1.00 22.79  ? 260 PHE C CZ  1 
ATOM   6499  N  N   . ILE C 1 261 ? 6.345   1.565   -0.104  1.00 19.62  ? 261 ILE C N   1 
ATOM   6500  C  CA  . ILE C 1 261 ? 7.388   1.647   -1.101  1.00 21.61  ? 261 ILE C CA  1 
ATOM   6501  C  C   . ILE C 1 261 ? 7.914   0.226   -1.301  1.00 20.97  ? 261 ILE C C   1 
ATOM   6502  O  O   . ILE C 1 261 ? 8.145   -0.496  -0.353  1.00 23.42  ? 261 ILE C O   1 
ATOM   6503  C  CB  . ILE C 1 261 ? 8.477   2.667   -0.731  1.00 23.64  ? 261 ILE C CB  1 
ATOM   6504  C  CG1 . ILE C 1 261 ? 9.506   2.750   -1.826  1.00 27.94  ? 261 ILE C CG1 1 
ATOM   6505  C  CG2 . ILE C 1 261 ? 9.173   2.331   0.575   1.00 23.77  ? 261 ILE C CG2 1 
ATOM   6506  C  CD1 . ILE C 1 261 ? 10.472  3.911   -1.676  1.00 28.71  ? 261 ILE C CD1 1 
ATOM   6507  N  N   . GLY C 1 262 ? 8.034   -0.195  -2.544  1.00 19.33  ? 262 GLY C N   1 
ATOM   6508  C  CA  . GLY C 1 262 ? 8.597   -1.487  -2.873  1.00 20.94  ? 262 GLY C CA  1 
ATOM   6509  C  C   . GLY C 1 262 ? 9.662   -1.397  -3.975  1.00 21.50  ? 262 GLY C C   1 
ATOM   6510  O  O   . GLY C 1 262 ? 9.478   -0.842  -5.052  1.00 24.23  ? 262 GLY C O   1 
ATOM   6511  N  N   . TYR C 1 263 ? 10.807  -1.991  -3.702  1.00 22.03  ? 263 TYR C N   1 
ATOM   6512  C  CA  . TYR C 1 263 ? 11.845  -2.038  -4.688  1.00 21.86  ? 263 TYR C CA  1 
ATOM   6513  C  C   . TYR C 1 263 ? 11.852  -3.413  -5.330  1.00 25.81  ? 263 TYR C C   1 
ATOM   6514  O  O   . TYR C 1 263 ? 11.635  -4.416  -4.634  1.00 24.66  ? 263 TYR C O   1 
ATOM   6515  C  CB  . TYR C 1 263 ? 13.135  -1.783  -3.940  1.00 21.91  ? 263 TYR C CB  1 
ATOM   6516  C  CG  . TYR C 1 263 ? 13.343  -0.361  -3.457  1.00 22.76  ? 263 TYR C CG  1 
ATOM   6517  C  CD1 . TYR C 1 263 ? 14.000  0.569   -4.249  1.00 21.47  ? 263 TYR C CD1 1 
ATOM   6518  C  CD2 . TYR C 1 263 ? 12.980  0.012   -2.178  1.00 21.49  ? 263 TYR C CD2 1 
ATOM   6519  C  CE1 . TYR C 1 263 ? 14.295  1.829   -3.779  1.00 21.69  ? 263 TYR C CE1 1 
ATOM   6520  C  CE2 . TYR C 1 263 ? 13.261  1.281   -1.696  1.00 20.79  ? 263 TYR C CE2 1 
ATOM   6521  C  CZ  . TYR C 1 263 ? 13.941  2.176   -2.492  1.00 21.53  ? 263 TYR C CZ  1 
ATOM   6522  O  OH  . TYR C 1 263 ? 14.224  3.441   -2.065  1.00 23.02  ? 263 TYR C OH  1 
ATOM   6523  N  N   . ALA C 1 264 ? 12.152  -3.434  -6.643  1.00 30.24  ? 264 ALA C N   1 
ATOM   6524  C  CA  . ALA C 1 264 ? 12.331  -4.674  -7.395  1.00 30.20  ? 264 ALA C CA  1 
ATOM   6525  C  C   . ALA C 1 264 ? 13.290  -4.458  -8.568  1.00 33.96  ? 264 ALA C C   1 
ATOM   6526  O  O   . ALA C 1 264 ? 13.476  -3.315  -9.021  1.00 32.84  ? 264 ALA C O   1 
ATOM   6527  C  CB  . ALA C 1 264 ? 10.972  -5.148  -7.854  1.00 30.22  ? 264 ALA C CB  1 
ATOM   6528  N  N   . ARG C 1 265 ? 13.908  -5.559  -9.052  1.00 35.65  ? 265 ARG C N   1 
ATOM   6529  C  CA  . ARG C 1 265 ? 14.903  -5.478  -10.120 1.00 37.91  ? 265 ARG C CA  1 
ATOM   6530  C  C   . ARG C 1 265 ? 14.237  -5.216  -11.466 1.00 32.24  ? 265 ARG C C   1 
ATOM   6531  O  O   . ARG C 1 265 ? 14.888  -4.733  -12.380 1.00 36.27  ? 265 ARG C O   1 
ATOM   6532  C  CB  . ARG C 1 265 ? 15.827  -6.694  -10.238 1.00 39.14  ? 265 ARG C CB  1 
ATOM   6533  C  CG  . ARG C 1 265 ? 15.146  -7.921  -10.814 1.00 43.02  ? 265 ARG C CG  1 
ATOM   6534  C  CD  . ARG C 1 265 ? 16.081  -9.114  -10.701 1.00 49.60  ? 265 ARG C CD  1 
ATOM   6535  N  NE  . ARG C 1 265 ? 17.251  -8.856  -11.546 1.00 54.87  ? 265 ARG C NE  1 
ATOM   6536  C  CZ  . ARG C 1 265 ? 18.406  -9.477  -11.490 1.00 54.21  ? 265 ARG C CZ  1 
ATOM   6537  N  NH1 . ARG C 1 265 ? 18.642  -10.361 -10.558 1.00 63.04  ? 265 ARG C NH1 1 
ATOM   6538  N  NH2 . ARG C 1 265 ? 19.349  -9.201  -12.360 1.00 59.83  ? 265 ARG C NH2 1 
ATOM   6539  N  N   . THR C 1 266 ? 12.950  -5.514  -11.557 1.00 29.85  ? 266 THR C N   1 
ATOM   6540  C  CA  . THR C 1 266 ? 12.115  -5.163  -12.690 1.00 33.52  ? 266 THR C CA  1 
ATOM   6541  C  C   . THR C 1 266 ? 10.754  -4.765  -12.147 1.00 29.23  ? 266 THR C C   1 
ATOM   6542  O  O   . THR C 1 266 ? 10.241  -5.401  -11.255 1.00 30.99  ? 266 THR C O   1 
ATOM   6543  C  CB  . THR C 1 266 ? 11.942  -6.345  -13.653 1.00 38.28  ? 266 THR C CB  1 
ATOM   6544  O  OG1 . THR C 1 266 ? 10.755  -6.109  -14.415 1.00 49.98  ? 266 THR C OG1 1 
ATOM   6545  C  CG2 . THR C 1 266 ? 11.611  -7.670  -12.996 1.00 37.79  ? 266 THR C CG2 1 
ATOM   6546  N  N   . PRO C 1 267 ? 10.083  -3.767  -12.724 1.00 29.51  ? 267 PRO C N   1 
ATOM   6547  C  CA  . PRO C 1 267 ? 8.741   -3.436  -12.273 1.00 32.29  ? 267 PRO C CA  1 
ATOM   6548  C  C   . PRO C 1 267 ? 7.686   -4.489  -12.608 1.00 37.79  ? 267 PRO C C   1 
ATOM   6549  O  O   . PRO C 1 267 ? 6.604   -4.397  -12.013 1.00 36.01  ? 267 PRO C O   1 
ATOM   6550  C  CB  . PRO C 1 267 ? 8.425   -2.086  -12.907 1.00 33.88  ? 267 PRO C CB  1 
ATOM   6551  C  CG  . PRO C 1 267 ? 9.466   -1.916  -13.998 1.00 34.56  ? 267 PRO C CG  1 
ATOM   6552  C  CD  . PRO C 1 267 ? 10.594  -2.906  -13.789 1.00 30.75  ? 267 PRO C CD  1 
ATOM   6553  N  N   . GLU C 1 268 ? 7.980   -5.452  -13.530 1.00 42.15  ? 268 GLU C N   1 
ATOM   6554  C  CA  . GLU C 1 268 ? 6.996   -6.488  -13.896 1.00 40.76  ? 268 GLU C CA  1 
ATOM   6555  C  C   . GLU C 1 268 ? 6.526   -7.208  -12.601 1.00 35.31  ? 268 GLU C C   1 
ATOM   6556  O  O   . GLU C 1 268 ? 5.338   -7.492  -12.424 1.00 33.18  ? 268 GLU C O   1 
ATOM   6557  C  CB  . GLU C 1 268 ? 7.369   -7.485  -15.021 1.00 39.96  ? 268 GLU C CB  1 
ATOM   6558  C  CG  . GLU C 1 268 ? 7.784   -6.951  -16.397 1.00 42.59  ? 268 GLU C CG  1 
ATOM   6559  N  N   . VAL C 1 269 ? 7.437   -7.459  -11.648 1.00 29.87  ? 269 VAL C N   1 
ATOM   6560  C  CA  . VAL C 1 269 ? 7.089   -8.166  -10.419 1.00 29.94  ? 269 VAL C CA  1 
ATOM   6561  C  C   . VAL C 1 269 ? 6.095   -7.365  -9.576  1.00 32.77  ? 269 VAL C C   1 
ATOM   6562  O  O   . VAL C 1 269 ? 5.039   -7.891  -9.197  1.00 31.00  ? 269 VAL C O   1 
ATOM   6563  C  CB  . VAL C 1 269 ? 8.373   -8.442  -9.617  1.00 31.64  ? 269 VAL C CB  1 
ATOM   6564  C  CG1 . VAL C 1 269 ? 8.087   -9.118  -8.298  1.00 33.01  ? 269 VAL C CG1 1 
ATOM   6565  C  CG2 . VAL C 1 269 ? 9.378   -9.264  -10.402 1.00 35.98  ? 269 VAL C CG2 1 
ATOM   6566  N  N   . THR C 1 270 ? 6.467   -6.102  -9.254  1.00 35.12  ? 270 THR C N   1 
ATOM   6567  C  CA  . THR C 1 270 ? 5.646   -5.203  -8.452  1.00 32.93  ? 270 THR C CA  1 
ATOM   6568  C  C   . THR C 1 270 ? 4.272   -5.028  -9.126  1.00 33.88  ? 270 THR C C   1 
ATOM   6569  O  O   . THR C 1 270 ? 3.226   -5.115  -8.468  1.00 34.32  ? 270 THR C O   1 
ATOM   6570  C  CB  . THR C 1 270 ? 6.382   -3.875  -8.215  1.00 36.19  ? 270 THR C CB  1 
ATOM   6571  O  OG1 . THR C 1 270 ? 7.772   -4.029  -7.893  1.00 35.87  ? 270 THR C OG1 1 
ATOM   6572  C  CG2 . THR C 1 270 ? 5.702   -3.067  -7.115  1.00 33.42  ? 270 THR C CG2 1 
ATOM   6573  N  N   . GLU C 1 271 ? 4.262   -4.822  -10.458 1.00 33.91  ? 271 GLU C N   1 
ATOM   6574  C  CA  . GLU C 1 271 ? 3.036   -4.571  -11.223 1.00 33.83  ? 271 GLU C CA  1 
ATOM   6575  C  C   . GLU C 1 271 ? 2.088   -5.784  -11.228 1.00 32.23  ? 271 GLU C C   1 
ATOM   6576  O  O   . GLU C 1 271 ? 0.866   -5.640  -11.240 1.00 28.35  ? 271 GLU C O   1 
ATOM   6577  C  CB  . GLU C 1 271 ? 3.401   -4.150  -12.656 1.00 32.72  ? 271 GLU C CB  1 
ATOM   6578  C  CG  . GLU C 1 271 ? 3.781   -2.676  -12.766 1.00 32.90  ? 271 GLU C CG  1 
ATOM   6579  C  CD  . GLU C 1 271 ? 4.517   -2.193  -13.996 1.00 32.30  ? 271 GLU C CD  1 
ATOM   6580  O  OE1 . GLU C 1 271 ? 4.825   -2.957  -14.892 1.00 36.99  ? 271 GLU C OE1 1 
ATOM   6581  O  OE2 . GLU C 1 271 ? 4.821   -1.016  -14.035 1.00 34.46  ? 271 GLU C OE2 1 
ATOM   6582  N  N   . THR C 1 272 ? 2.643   -6.992  -11.223 1.00 31.90  ? 272 THR C N   1 
ATOM   6583  C  CA  . THR C 1 272 ? 1.812   -8.178  -11.163 1.00 30.96  ? 272 THR C CA  1 
ATOM   6584  C  C   . THR C 1 272 ? 1.085   -8.227  -9.827  1.00 31.50  ? 272 THR C C   1 
ATOM   6585  O  O   . THR C 1 272 ? -0.121  -8.465  -9.773  1.00 31.41  ? 272 THR C O   1 
ATOM   6586  C  CB  . THR C 1 272 ? 2.676   -9.421  -11.288 1.00 32.75  ? 272 THR C CB  1 
ATOM   6587  O  OG1 . THR C 1 272 ? 3.193   -9.352  -12.604 1.00 34.58  ? 272 THR C OG1 1 
ATOM   6588  C  CG2 . THR C 1 272 ? 1.885   -10.691 -11.065 1.00 32.12  ? 272 THR C CG2 1 
ATOM   6589  N  N   . MET C 1 273 ? 1.824   -8.022  -8.733  1.00 30.60  ? 273 MET C N   1 
ATOM   6590  C  CA  . MET C 1 273 ? 1.216   -8.056  -7.408  1.00 29.47  ? 273 MET C CA  1 
ATOM   6591  C  C   . MET C 1 273 ? 0.079   -7.040  -7.326  1.00 31.03  ? 273 MET C C   1 
ATOM   6592  O  O   . MET C 1 273 ? -0.991  -7.311  -6.769  1.00 32.24  ? 273 MET C O   1 
ATOM   6593  C  CB  . MET C 1 273 ? 2.270   -7.739  -6.351  1.00 30.76  ? 273 MET C CB  1 
ATOM   6594  C  CG  . MET C 1 273 ? 3.332   -8.815  -6.252  1.00 32.25  ? 273 MET C CG  1 
ATOM   6595  S  SD  . MET C 1 273 ? 4.580   -8.388  -5.032  1.00 32.46  ? 273 MET C SD  1 
ATOM   6596  C  CE  . MET C 1 273 ? 5.705   -9.788  -5.061  1.00 29.56  ? 273 MET C CE  1 
ATOM   6597  N  N   . LEU C 1 274 ? 0.315   -5.881  -7.944  1.00 29.39  ? 274 LEU C N   1 
ATOM   6598  C  CA  . LEU C 1 274 ? -0.672  -4.825  -7.961  1.00 32.44  ? 274 LEU C CA  1 
ATOM   6599  C  C   . LEU C 1 274 ? -1.908  -5.224  -8.767  1.00 30.76  ? 274 LEU C C   1 
ATOM   6600  O  O   . LEU C 1 274 ? -3.014  -4.890  -8.338  1.00 24.96  ? 274 LEU C O   1 
ATOM   6601  C  CB  . LEU C 1 274 ? -0.038  -3.547  -8.518  1.00 34.15  ? 274 LEU C CB  1 
ATOM   6602  C  CG  . LEU C 1 274 ? 0.805   -2.725  -7.540  1.00 32.40  ? 274 LEU C CG  1 
ATOM   6603  C  CD1 . LEU C 1 274 ? 1.439   -1.589  -8.319  1.00 32.03  ? 274 LEU C CD1 1 
ATOM   6604  C  CD2 . LEU C 1 274 ? -0.003  -2.213  -6.367  1.00 32.48  ? 274 LEU C CD2 1 
ATOM   6605  N  N   . GLU C 1 275 ? -1.712  -5.873  -9.934  1.00 31.52  ? 275 GLU C N   1 
ATOM   6606  C  CA  . GLU C 1 275 ? -2.843  -6.345  -10.736 1.00 38.99  ? 275 GLU C CA  1 
ATOM   6607  C  C   . GLU C 1 275 ? -3.704  -7.350  -9.944  1.00 34.93  ? 275 GLU C C   1 
ATOM   6608  O  O   . GLU C 1 275 ? -4.936  -7.219  -9.863  1.00 30.37  ? 275 GLU C O   1 
ATOM   6609  C  CB  . GLU C 1 275 ? -2.450  -7.027  -12.042 1.00 37.19  ? 275 GLU C CB  1 
ATOM   6610  C  CG  . GLU C 1 275 ? -1.941  -6.061  -13.103 1.00 46.44  ? 275 GLU C CG  1 
ATOM   6611  C  CD  . GLU C 1 275 ? -1.456  -6.736  -14.387 1.00 48.13  ? 275 GLU C CD  1 
ATOM   6612  O  OE1 . GLU C 1 275 ? -1.743  -7.924  -14.585 1.00 51.45  ? 275 GLU C OE1 1 
ATOM   6613  O  OE2 . GLU C 1 275 ? -0.813  -6.086  -15.230 1.00 56.92  ? 275 GLU C OE2 1 
ATOM   6614  N  N   . ARG C 1 276 ? -3.042  -8.336  -9.327  1.00 30.98  ? 276 ARG C N   1 
ATOM   6615  C  CA  . ARG C 1 276 ? -3.742  -9.294  -8.488  1.00 35.42  ? 276 ARG C CA  1 
ATOM   6616  C  C   . ARG C 1 276 ? -4.561  -8.599  -7.409  1.00 34.57  ? 276 ARG C C   1 
ATOM   6617  O  O   . ARG C 1 276 ? -5.692  -8.997  -7.172  1.00 36.60  ? 276 ARG C O   1 
ATOM   6618  C  CB  . ARG C 1 276 ? -2.767  -10.307 -7.900  1.00 34.43  ? 276 ARG C CB  1 
ATOM   6619  C  CG  . ARG C 1 276 ? -2.495  -11.284 -9.023  1.00 32.81  ? 276 ARG C CG  1 
ATOM   6620  C  CD  . ARG C 1 276 ? -1.173  -11.951 -8.892  1.00 38.94  ? 276 ARG C CD  1 
ATOM   6621  N  NE  . ARG C 1 276 ? -1.117  -12.810 -7.701  1.00 49.82  ? 276 ARG C NE  1 
ATOM   6622  C  CZ  . ARG C 1 276 ? -1.688  -13.997 -7.551  1.00 48.49  ? 276 ARG C CZ  1 
ATOM   6623  N  NH1 . ARG C 1 276 ? -2.311  -14.549 -8.572  1.00 55.92  ? 276 ARG C NH1 1 
ATOM   6624  N  NH2 . ARG C 1 276 ? -1.638  -14.624 -6.392  1.00 40.60  ? 276 ARG C NH2 1 
ATOM   6625  N  N   . MET C 1 277 ? -3.994  -7.571  -6.776  1.00 32.28  ? 277 MET C N   1 
ATOM   6626  C  CA  . MET C 1 277 ? -4.667  -6.881  -5.690  1.00 31.29  ? 277 MET C CA  1 
ATOM   6627  C  C   . MET C 1 277 ? -5.880  -6.089  -6.194  1.00 29.23  ? 277 MET C C   1 
ATOM   6628  O  O   . MET C 1 277 ? -6.944  -6.135  -5.562  1.00 30.50  ? 277 MET C O   1 
ATOM   6629  C  CB  . MET C 1 277 ? -3.702  -5.922  -4.962  1.00 32.11  ? 277 MET C CB  1 
ATOM   6630  C  CG  . MET C 1 277 ? -2.668  -6.564  -4.047  1.00 28.50  ? 277 MET C CG  1 
ATOM   6631  S  SD  . MET C 1 277 ? -1.526  -5.301  -3.430  1.00 27.68  ? 277 MET C SD  1 
ATOM   6632  C  CE  . MET C 1 277 ? -2.599  -4.257  -2.434  1.00 27.30  ? 277 MET C CE  1 
ATOM   6633  N  N   . PHE C 1 278 ? -5.715  -5.339  -7.309  1.00 28.13  ? 278 PHE C N   1 
ATOM   6634  C  CA  . PHE C 1 278 ? -6.736  -4.381  -7.722  1.00 28.70  ? 278 PHE C CA  1 
ATOM   6635  C  C   . PHE C 1 278 ? -7.761  -5.026  -8.658  1.00 29.98  ? 278 PHE C C   1 
ATOM   6636  O  O   . PHE C 1 278 ? -8.939  -4.690  -8.626  1.00 28.37  ? 278 PHE C O   1 
ATOM   6637  C  CB  . PHE C 1 278 ? -6.088  -3.129  -8.328  1.00 26.38  ? 278 PHE C CB  1 
ATOM   6638  C  CG  . PHE C 1 278 ? -5.636  -2.162  -7.237  1.00 26.06  ? 278 PHE C CG  1 
ATOM   6639  C  CD1 . PHE C 1 278 ? -6.524  -1.280  -6.655  1.00 28.32  ? 278 PHE C CD1 1 
ATOM   6640  C  CD2 . PHE C 1 278 ? -4.346  -2.189  -6.727  1.00 29.68  ? 278 PHE C CD2 1 
ATOM   6641  C  CE1 . PHE C 1 278 ? -6.123  -0.388  -5.678  1.00 27.30  ? 278 PHE C CE1 1 
ATOM   6642  C  CE2 . PHE C 1 278 ? -3.956  -1.321  -5.726  1.00 26.58  ? 278 PHE C CE2 1 
ATOM   6643  C  CZ  . PHE C 1 278 ? -4.851  -0.442  -5.191  1.00 27.05  ? 278 PHE C CZ  1 
ATOM   6644  N  N   . LEU C 1 279 ? -7.308  -5.945  -9.505  1.00 31.40  ? 279 LEU C N   1 
ATOM   6645  C  CA  . LEU C 1 279 ? -8.189  -6.501  -10.511 1.00 34.07  ? 279 LEU C CA  1 
ATOM   6646  C  C   . LEU C 1 279 ? -8.659  -7.900  -10.156 1.00 39.29  ? 279 LEU C C   1 
ATOM   6647  O  O   . LEU C 1 279 ? -9.652  -8.345  -10.697 1.00 46.75  ? 279 LEU C O   1 
ATOM   6648  C  CB  . LEU C 1 279 ? -7.398  -6.529  -11.804 1.00 35.18  ? 279 LEU C CB  1 
ATOM   6649  C  CG  . LEU C 1 279 ? -6.906  -5.158  -12.254 1.00 39.46  ? 279 LEU C CG  1 
ATOM   6650  C  CD1 . LEU C 1 279 ? -6.220  -5.448  -13.562 1.00 39.59  ? 279 LEU C CD1 1 
ATOM   6651  C  CD2 . LEU C 1 279 ? -8.003  -4.083  -12.348 1.00 40.73  ? 279 LEU C CD2 1 
ATOM   6652  N  N   . GLY C 1 280 ? -7.934  -8.608  -9.303  1.00 40.93  ? 280 GLY C N   1 
ATOM   6653  C  CA  . GLY C 1 280 ? -8.434  -9.873  -8.807  1.00 46.35  ? 280 GLY C CA  1 
ATOM   6654  C  C   . GLY C 1 280 ? -7.838  -11.031 -9.600  1.00 45.32  ? 280 GLY C C   1 
ATOM   6655  O  O   . GLY C 1 280 ? -7.007  -10.806 -10.477 1.00 44.20  ? 280 GLY C O   1 
ATOM   6656  N  N   . THR C 1 281 ? -8.241  -12.259 -9.228  1.00 48.65  ? 281 THR C N   1 
ATOM   6657  C  CA  . THR C 1 281 ? -7.838  -13.473 -9.926  1.00 46.27  ? 281 THR C CA  1 
ATOM   6658  C  C   . THR C 1 281 ? -9.089  -14.261 -10.273 1.00 49.65  ? 281 THR C C   1 
ATOM   6659  O  O   . THR C 1 281 ? -10.196 -13.763 -10.072 1.00 40.41  ? 281 THR C O   1 
ATOM   6660  C  CB  . THR C 1 281 ? -6.921  -14.342 -9.075  1.00 41.86  ? 281 THR C CB  1 
ATOM   6661  O  OG1 . THR C 1 281 ? -7.746  -14.742 -7.989  1.00 44.27  ? 281 THR C OG1 1 
ATOM   6662  C  CG2 . THR C 1 281 ? -5.683  -13.588 -8.638  1.00 45.36  ? 281 THR C CG2 1 
ATOM   6663  N  N   . ALA C 1 282 ? -8.866  -15.501 -10.739 1.00 59.49  ? 282 ALA C N   1 
ATOM   6664  C  CA  . ALA C 1 282 ? -9.939  -16.469 -10.913 1.00 60.86  ? 282 ALA C CA  1 
ATOM   6665  C  C   . ALA C 1 282 ? -10.753 -16.601 -9.624  1.00 54.31  ? 282 ALA C C   1 
ATOM   6666  O  O   . ALA C 1 282 ? -11.958 -16.456 -9.699  1.00 41.40  ? 282 ALA C O   1 
ATOM   6667  C  CB  . ALA C 1 282 ? -9.402  -17.804 -11.419 1.00 66.31  ? 282 ALA C CB  1 
ATOM   6668  N  N   . SER C 1 283 ? -10.108 -16.774 -8.452  1.00 56.91  ? 283 SER C N   1 
ATOM   6669  C  CA  . SER C 1 283 ? -10.804 -17.149 -7.228  1.00 50.50  ? 283 SER C CA  1 
ATOM   6670  C  C   . SER C 1 283 ? -10.964 -16.020 -6.215  1.00 49.88  ? 283 SER C C   1 
ATOM   6671  O  O   . SER C 1 283 ? -11.330 -16.301 -5.087  1.00 52.59  ? 283 SER C O   1 
ATOM   6672  C  CB  . SER C 1 283 ? -10.063 -18.265 -6.602  1.00 55.47  ? 283 SER C CB  1 
ATOM   6673  O  OG  . SER C 1 283 ? -9.998  -19.323 -7.546  1.00 65.40  ? 283 SER C OG  1 
ATOM   6674  N  N   . ALA C 1 284 ? -10.647 -14.768 -6.566  1.00 51.51  ? 284 ALA C N   1 
ATOM   6675  C  CA  . ALA C 1 284 ? -10.675 -13.675 -5.598  1.00 43.09  ? 284 ALA C CA  1 
ATOM   6676  C  C   . ALA C 1 284 ? -10.978 -12.357 -6.288  1.00 38.30  ? 284 ALA C C   1 
ATOM   6677  O  O   . ALA C 1 284 ? -10.249 -11.982 -7.203  1.00 41.51  ? 284 ALA C O   1 
ATOM   6678  C  CB  . ALA C 1 284 ? -9.340  -13.573 -4.904  1.00 47.35  ? 284 ALA C CB  1 
ATOM   6679  N  N   . PRO C 1 285 ? -12.037 -11.630 -5.868  1.00 35.16  ? 285 PRO C N   1 
ATOM   6680  C  CA  . PRO C 1 285 ? -12.429 -10.360 -6.490  1.00 33.63  ? 285 PRO C CA  1 
ATOM   6681  C  C   . PRO C 1 285 ? -11.350 -9.283  -6.473  1.00 38.01  ? 285 PRO C C   1 
ATOM   6682  O  O   . PRO C 1 285 ? -11.090 -8.611  -7.462  1.00 35.88  ? 285 PRO C O   1 
ATOM   6683  C  CB  . PRO C 1 285 ? -13.690 -9.891  -5.706  1.00 33.84  ? 285 PRO C CB  1 
ATOM   6684  C  CG  . PRO C 1 285 ? -13.642 -10.671 -4.424  1.00 41.15  ? 285 PRO C CG  1 
ATOM   6685  C  CD  . PRO C 1 285 ? -12.930 -12.005 -4.766  1.00 38.07  ? 285 PRO C CD  1 
ATOM   6686  N  N   . HIS C 1 286 ? -10.752 -9.081  -5.302  1.00 42.17  ? 286 HIS C N   1 
ATOM   6687  C  CA  . HIS C 1 286 ? -9.718  -8.077  -5.105  1.00 37.99  ? 286 HIS C CA  1 
ATOM   6688  C  C   . HIS C 1 286 ? -9.157  -8.333  -3.726  1.00 35.83  ? 286 HIS C C   1 
ATOM   6689  O  O   . HIS C 1 286 ? -9.722  -9.155  -3.017  1.00 48.17  ? 286 HIS C O   1 
ATOM   6690  C  CB  . HIS C 1 286 ? -10.270 -6.662  -5.210  1.00 32.04  ? 286 HIS C CB  1 
ATOM   6691  C  CG  . HIS C 1 286 ? -11.378 -6.406  -4.277  1.00 33.40  ? 286 HIS C CG  1 
ATOM   6692  N  ND1 . HIS C 1 286 ? -12.690 -6.378  -4.685  1.00 37.92  ? 286 HIS C ND1 1 
ATOM   6693  C  CD2 . HIS C 1 286 ? -11.400 -6.121  -2.981  1.00 35.81  ? 286 HIS C CD2 1 
ATOM   6694  C  CE1 . HIS C 1 286 ? -13.464 -6.060  -3.646  1.00 35.10  ? 286 HIS C CE1 1 
ATOM   6695  N  NE2 . HIS C 1 286 ? -12.709 -5.897  -2.600  1.00 32.61  ? 286 HIS C NE2 1 
ATOM   6696  N  N   . ASP C 1 287 ? -8.038  -7.684  -3.390  1.00 36.69  ? 287 ASP C N   1 
ATOM   6697  C  CA  . ASP C 1 287 ? -7.403  -7.855  -2.086  1.00 32.65  ? 287 ASP C CA  1 
ATOM   6698  C  C   . ASP C 1 287 ? -8.283  -7.193  -1.027  1.00 32.59  ? 287 ASP C C   1 
ATOM   6699  O  O   . ASP C 1 287 ? -8.565  -5.998  -1.076  1.00 32.18  ? 287 ASP C O   1 
ATOM   6700  C  CB  . ASP C 1 287 ? -5.989  -7.308  -2.123  1.00 34.01  ? 287 ASP C CB  1 
ATOM   6701  C  CG  . ASP C 1 287 ? -5.107  -7.573  -0.917  1.00 32.97  ? 287 ASP C CG  1 
ATOM   6702  O  OD1 . ASP C 1 287 ? -5.633  -7.745  0.193   1.00 33.96  ? 287 ASP C OD1 1 
ATOM   6703  O  OD2 . ASP C 1 287 ? -3.891  -7.640  -1.126  1.00 30.56  ? 287 ASP C OD2 1 
ATOM   6704  N  N   . ARG C 1 288 ? -8.712  -7.972  -0.033  1.00 30.34  ? 288 ARG C N   1 
ATOM   6705  C  CA  . ARG C 1 288 ? -9.605  -7.443  0.988   1.00 29.90  ? 288 ARG C CA  1 
ATOM   6706  C  C   . ARG C 1 288 ? -8.976  -6.266  1.725   1.00 26.73  ? 288 ARG C C   1 
ATOM   6707  O  O   . ARG C 1 288 ? -9.679  -5.473  2.341   1.00 24.67  ? 288 ARG C O   1 
ATOM   6708  C  CB  . ARG C 1 288 ? -9.910  -8.549  2.001   1.00 34.73  ? 288 ARG C CB  1 
ATOM   6709  C  CG  . ARG C 1 288 ? -10.845 -9.604  1.430   1.00 39.61  ? 288 ARG C CG  1 
ATOM   6710  C  CD  . ARG C 1 288 ? -12.276 -9.084  1.541   1.00 40.27  ? 288 ARG C CD  1 
ATOM   6711  N  NE  . ARG C 1 288 ? -12.781 -9.092  2.927   1.00 40.15  ? 288 ARG C NE  1 
ATOM   6712  C  CZ  . ARG C 1 288 ? -13.392 -8.084  3.600   1.00 41.33  ? 288 ARG C CZ  1 
ATOM   6713  N  NH1 . ARG C 1 288 ? -13.461 -6.850  3.118   1.00 41.28  ? 288 ARG C NH1 1 
ATOM   6714  N  NH2 . ARG C 1 288 ? -13.950 -8.294  4.789   1.00 39.41  ? 288 ARG C NH2 1 
ATOM   6715  N  N   . ILE C 1 289 ? -7.641  -6.165  1.703   1.00 27.16  ? 289 ILE C N   1 
ATOM   6716  C  CA  . ILE C 1 289 ? -7.012  -5.061  2.405   1.00 29.41  ? 289 ILE C CA  1 
ATOM   6717  C  C   . ILE C 1 289 ? -7.507  -3.747  1.817   1.00 26.82  ? 289 ILE C C   1 
ATOM   6718  O  O   . ILE C 1 289 ? -7.547  -2.752  2.534   1.00 25.41  ? 289 ILE C O   1 
ATOM   6719  C  CB  . ILE C 1 289 ? -5.474  -5.167  2.401   1.00 32.64  ? 289 ILE C CB  1 
ATOM   6720  C  CG1 . ILE C 1 289 ? -4.870  -4.495  3.656   1.00 33.62  ? 289 ILE C CG1 1 
ATOM   6721  C  CG2 . ILE C 1 289 ? -4.860  -4.628  1.097   1.00 29.89  ? 289 ILE C CG2 1 
ATOM   6722  C  CD1 . ILE C 1 289 ? -3.407  -4.860  3.876   1.00 36.74  ? 289 ILE C CD1 1 
ATOM   6723  N  N   . LEU C 1 290 ? -7.904  -3.750  0.532   1.00 29.57  ? 290 LEU C N   1 
ATOM   6724  C  CA  . LEU C 1 290 ? -8.298  -2.514  -0.146  1.00 31.94  ? 290 LEU C CA  1 
ATOM   6725  C  C   . LEU C 1 290 ? -9.685  -2.046  0.291   1.00 30.91  ? 290 LEU C C   1 
ATOM   6726  O  O   . LEU C 1 290 ? -10.083 -0.893  0.060   1.00 26.94  ? 290 LEU C O   1 
ATOM   6727  C  CB  . LEU C 1 290 ? -8.202  -2.716  -1.655  1.00 32.43  ? 290 LEU C CB  1 
ATOM   6728  C  CG  . LEU C 1 290 ? -6.810  -3.007  -2.215  1.00 29.09  ? 290 LEU C CG  1 
ATOM   6729  C  CD1 . LEU C 1 290 ? -6.898  -3.327  -3.703  1.00 31.29  ? 290 LEU C CD1 1 
ATOM   6730  C  CD2 . LEU C 1 290 ? -5.881  -1.845  -1.964  1.00 26.69  ? 290 LEU C CD2 1 
ATOM   6731  N  N   . ASP C 1 291 ? -10.397 -2.927  0.998   1.00 33.64  ? 291 ASP C N   1 
ATOM   6732  C  CA  . ASP C 1 291 ? -11.671 -2.541  1.595   1.00 35.70  ? 291 ASP C CA  1 
ATOM   6733  C  C   . ASP C 1 291 ? -11.455 -1.631  2.807   1.00 30.60  ? 291 ASP C C   1 
ATOM   6734  O  O   . ASP C 1 291 ? -12.417 -1.032  3.254   1.00 28.39  ? 291 ASP C O   1 
ATOM   6735  C  CB  . ASP C 1 291 ? -12.592 -3.740  1.829   1.00 36.50  ? 291 ASP C CB  1 
ATOM   6736  C  CG  . ASP C 1 291 ? -13.074 -4.466  0.569   1.00 36.71  ? 291 ASP C CG  1 
ATOM   6737  O  OD1 . ASP C 1 291 ? -13.306 -3.822  -0.466  1.00 43.76  ? 291 ASP C OD1 1 
ATOM   6738  O  OD2 . ASP C 1 291 ? -13.196 -5.690  0.605   1.00 41.86  ? 291 ASP C OD2 1 
ATOM   6739  N  N   . PHE C 1 292 ? -10.211 -1.501  3.305   1.00 27.19  ? 292 PHE C N   1 
ATOM   6740  C  CA  . PHE C 1 292 ? -9.912  -0.549  4.364   1.00 25.05  ? 292 PHE C CA  1 
ATOM   6741  C  C   . PHE C 1 292 ? -8.763  0.386   4.003   1.00 26.84  ? 292 PHE C C   1 
ATOM   6742  O  O   . PHE C 1 292 ? -8.272  1.065   4.876   1.00 31.30  ? 292 PHE C O   1 
ATOM   6743  C  CB  . PHE C 1 292 ? -9.563  -1.336  5.623   1.00 25.54  ? 292 PHE C CB  1 
ATOM   6744  C  CG  . PHE C 1 292 ? -10.594 -2.392  5.915   1.00 27.87  ? 292 PHE C CG  1 
ATOM   6745  C  CD1 . PHE C 1 292 ? -11.675 -2.091  6.725   1.00 29.29  ? 292 PHE C CD1 1 
ATOM   6746  C  CD2 . PHE C 1 292 ? -10.529 -3.650  5.321   1.00 31.24  ? 292 PHE C CD2 1 
ATOM   6747  C  CE1 . PHE C 1 292 ? -12.657 -3.039  6.945   1.00 27.65  ? 292 PHE C CE1 1 
ATOM   6748  C  CE2 . PHE C 1 292 ? -11.502 -4.619  5.582   1.00 30.28  ? 292 PHE C CE2 1 
ATOM   6749  C  CZ  . PHE C 1 292 ? -12.548 -4.311  6.407   1.00 26.92  ? 292 PHE C CZ  1 
ATOM   6750  N  N   . SER C 1 293 ? -8.345  0.448   2.739   1.00 29.61  ? 293 SER C N   1 
ATOM   6751  C  CA  . SER C 1 293 ? -7.152  1.180   2.335   1.00 27.50  ? 293 SER C CA  1 
ATOM   6752  C  C   . SER C 1 293 ? -7.348  1.797   0.958   1.00 28.41  ? 293 SER C C   1 
ATOM   6753  O  O   . SER C 1 293 ? -7.709  1.118   0.005   1.00 31.01  ? 293 SER C O   1 
ATOM   6754  C  CB  . SER C 1 293 ? -5.984  0.272   2.294   1.00 25.45  ? 293 SER C CB  1 
ATOM   6755  O  OG  . SER C 1 293 ? -5.950  -0.533  3.461   1.00 30.14  ? 293 SER C OG  1 
ATOM   6756  N  N   . THR C 1 294 ? -7.153  3.103   0.875   1.00 29.01  ? 294 THR C N   1 
ATOM   6757  C  CA  . THR C 1 294 ? -7.328  3.839   -0.367  1.00 27.94  ? 294 THR C CA  1 
ATOM   6758  C  C   . THR C 1 294 ? -5.972  4.377   -0.785  1.00 28.93  ? 294 THR C C   1 
ATOM   6759  O  O   . THR C 1 294 ? -5.397  5.130   0.015   1.00 31.05  ? 294 THR C O   1 
ATOM   6760  C  CB  . THR C 1 294 ? -8.236  5.042   -0.110  1.00 25.46  ? 294 THR C CB  1 
ATOM   6761  O  OG1 . THR C 1 294 ? -9.400  4.468   0.451   1.00 29.07  ? 294 THR C OG1 1 
ATOM   6762  C  CG2 . THR C 1 294 ? -8.503  5.856   -1.360  1.00 23.20  ? 294 THR C CG2 1 
ATOM   6763  N  N   . ALA C 1 295 ? -5.556  4.084   -2.031  1.00 27.39  ? 295 ALA C N   1 
ATOM   6764  C  CA  . ALA C 1 295 ? -4.349  4.660   -2.607  1.00 24.95  ? 295 ALA C CA  1 
ATOM   6765  C  C   . ALA C 1 295 ? -4.682  6.050   -3.090  1.00 24.61  ? 295 ALA C C   1 
ATOM   6766  O  O   . ALA C 1 295 ? -5.651  6.196   -3.780  1.00 24.52  ? 295 ALA C O   1 
ATOM   6767  C  CB  . ALA C 1 295 ? -3.873  3.822   -3.767  1.00 26.18  ? 295 ALA C CB  1 
ATOM   6768  N  N   . VAL C 1 296 ? -3.898  7.048   -2.734  1.00 27.73  ? 296 VAL C N   1 
ATOM   6769  C  CA  . VAL C 1 296 ? -4.135  8.416   -3.186  1.00 25.69  ? 296 VAL C CA  1 
ATOM   6770  C  C   . VAL C 1 296 ? -2.927  8.942   -3.975  1.00 25.83  ? 296 VAL C C   1 
ATOM   6771  O  O   . VAL C 1 296 ? -2.978  10.057  -4.469  1.00 26.16  ? 296 VAL C O   1 
ATOM   6772  C  CB  . VAL C 1 296 ? -4.528  9.382   -2.042  1.00 25.78  ? 296 VAL C CB  1 
ATOM   6773  C  CG1 . VAL C 1 296 ? -5.571  8.786   -1.136  1.00 26.36  ? 296 VAL C CG1 1 
ATOM   6774  C  CG2 . VAL C 1 296 ? -3.363  9.739   -1.169  1.00 27.97  ? 296 VAL C CG2 1 
ATOM   6775  N  N   . THR C 1 297 ? -1.823  8.191   -4.059  1.00 23.10  ? 297 THR C N   1 
ATOM   6776  C  CA  . THR C 1 297 ? -0.756  8.523   -4.983  1.00 22.59  ? 297 THR C CA  1 
ATOM   6777  C  C   . THR C 1 297 ? -0.295  7.213   -5.596  1.00 26.65  ? 297 THR C C   1 
ATOM   6778  O  O   . THR C 1 297 ? -0.675  6.098   -5.178  1.00 26.82  ? 297 THR C O   1 
ATOM   6779  C  CB  . THR C 1 297 ? 0.439   9.219   -4.328  1.00 24.88  ? 297 THR C CB  1 
ATOM   6780  O  OG1 . THR C 1 297 ? 1.083   8.359   -3.391  1.00 25.31  ? 297 THR C OG1 1 
ATOM   6781  C  CG2 . THR C 1 297 ? 0.097   10.460  -3.539  1.00 24.93  ? 297 THR C CG2 1 
ATOM   6782  N  N   . GLY C 1 298 ? 0.516   7.388   -6.641  1.00 26.28  ? 298 GLY C N   1 
ATOM   6783  C  CA  . GLY C 1 298 ? 1.130   6.240   -7.295  1.00 28.50  ? 298 GLY C CA  1 
ATOM   6784  C  C   . GLY C 1 298 ? 2.175   6.707   -8.304  1.00 25.80  ? 298 GLY C C   1 
ATOM   6785  O  O   . GLY C 1 298 ? 1.831   7.472   -9.186  1.00 26.82  ? 298 GLY C O   1 
ATOM   6786  N  N   . SER C 1 299 ? 3.432   6.276   -8.141  1.00 22.45  ? 299 SER C N   1 
ATOM   6787  C  CA  . SER C 1 299 ? 4.493   6.639   -9.050  1.00 20.67  ? 299 SER C CA  1 
ATOM   6788  C  C   . SER C 1 299 ? 5.489   5.506   -9.127  1.00 20.99  ? 299 SER C C   1 
ATOM   6789  O  O   . SER C 1 299 ? 5.643   4.747   -8.180  1.00 26.36  ? 299 SER C O   1 
ATOM   6790  C  CB  . SER C 1 299 ? 5.176   7.868   -8.614  1.00 21.55  ? 299 SER C CB  1 
ATOM   6791  O  OG  . SER C 1 299 ? 4.262   8.894   -8.253  1.00 24.56  ? 299 SER C OG  1 
ATOM   6792  N  N   . LEU C 1 300 ? 6.198   5.461   -10.244 1.00 23.56  ? 300 LEU C N   1 
ATOM   6793  C  CA  . LEU C 1 300 ? 7.296   4.531   -10.442 1.00 26.90  ? 300 LEU C CA  1 
ATOM   6794  C  C   . LEU C 1 300 ? 8.579   5.321   -10.733 1.00 26.87  ? 300 LEU C C   1 
ATOM   6795  O  O   . LEU C 1 300 ? 8.549   6.358   -11.408 1.00 31.43  ? 300 LEU C O   1 
ATOM   6796  C  CB  . LEU C 1 300 ? 6.833   3.607   -11.565 1.00 26.72  ? 300 LEU C CB  1 
ATOM   6797  C  CG  . LEU C 1 300 ? 7.725   2.410   -11.901 1.00 32.05  ? 300 LEU C CG  1 
ATOM   6798  C  CD1 . LEU C 1 300 ? 7.023   1.634   -12.979 1.00 34.50  ? 300 LEU C CD1 1 
ATOM   6799  C  CD2 . LEU C 1 300 ? 9.094   2.742   -12.443 1.00 35.62  ? 300 LEU C CD2 1 
ATOM   6800  N  N   . PHE C 1 301 ? 9.695   4.854   -10.164 1.00 24.02  ? 301 PHE C N   1 
ATOM   6801  C  CA  . PHE C 1 301 ? 10.979  5.509   -10.357 1.00 24.31  ? 301 PHE C CA  1 
ATOM   6802  C  C   . PHE C 1 301 ? 12.075  4.474   -10.561 1.00 24.86  ? 301 PHE C C   1 
ATOM   6803  O  O   . PHE C 1 301 ? 11.982  3.357   -10.058 1.00 25.95  ? 301 PHE C O   1 
ATOM   6804  C  CB  . PHE C 1 301 ? 11.401  6.329   -9.129  1.00 22.55  ? 301 PHE C CB  1 
ATOM   6805  C  CG  . PHE C 1 301 ? 10.377  7.348   -8.688  1.00 19.95  ? 301 PHE C CG  1 
ATOM   6806  C  CD1 . PHE C 1 301 ? 10.413  8.629   -9.201  1.00 21.94  ? 301 PHE C CD1 1 
ATOM   6807  C  CD2 . PHE C 1 301 ? 9.389   7.011   -7.787  1.00 19.49  ? 301 PHE C CD2 1 
ATOM   6808  C  CE1 . PHE C 1 301 ? 9.480   9.577   -8.778  1.00 23.70  ? 301 PHE C CE1 1 
ATOM   6809  C  CE2 . PHE C 1 301 ? 8.481   7.952   -7.338  1.00 20.41  ? 301 PHE C CE2 1 
ATOM   6810  C  CZ  . PHE C 1 301 ? 8.511   9.240   -7.859  1.00 23.33  ? 301 PHE C CZ  1 
ATOM   6811  N  N   . PHE C 1 302 ? 13.135  4.900   -11.246 1.00 22.34  ? 302 PHE C N   1 
ATOM   6812  C  CA  . PHE C 1 302 ? 14.364  4.135   -11.310 1.00 23.23  ? 302 PHE C CA  1 
ATOM   6813  C  C   . PHE C 1 302 ? 15.396  4.786   -10.391 1.00 22.03  ? 302 PHE C C   1 
ATOM   6814  O  O   . PHE C 1 302 ? 15.608  5.977   -10.467 1.00 22.43  ? 302 PHE C O   1 
ATOM   6815  C  CB  . PHE C 1 302 ? 14.861  4.100   -12.758 1.00 24.77  ? 302 PHE C CB  1 
ATOM   6816  C  CG  . PHE C 1 302 ? 16.116  3.271   -12.940 1.00 24.27  ? 302 PHE C CG  1 
ATOM   6817  C  CD1 . PHE C 1 302 ? 16.053  1.879   -12.850 1.00 27.92  ? 302 PHE C CD1 1 
ATOM   6818  C  CD2 . PHE C 1 302 ? 17.333  3.873   -13.192 1.00 24.13  ? 302 PHE C CD2 1 
ATOM   6819  C  CE1 . PHE C 1 302 ? 17.193  1.103   -12.950 1.00 25.31  ? 302 PHE C CE1 1 
ATOM   6820  C  CE2 . PHE C 1 302 ? 18.468  3.094   -13.314 1.00 26.14  ? 302 PHE C CE2 1 
ATOM   6821  C  CZ  . PHE C 1 302 ? 18.387  1.713   -13.207 1.00 25.58  ? 302 PHE C CZ  1 
ATOM   6822  N  N   . THR C 1 303 ? 16.017  3.987   -9.523  1.00 23.28  ? 303 THR C N   1 
ATOM   6823  C  CA  . THR C 1 303 ? 17.048  4.428   -8.612  1.00 23.69  ? 303 THR C CA  1 
ATOM   6824  C  C   . THR C 1 303 ? 18.378  3.912   -9.165  1.00 27.18  ? 303 THR C C   1 
ATOM   6825  O  O   . THR C 1 303 ? 18.785  2.762   -8.942  1.00 32.19  ? 303 THR C O   1 
ATOM   6826  C  CB  . THR C 1 303 ? 16.800  3.924   -7.187  1.00 24.79  ? 303 THR C CB  1 
ATOM   6827  O  OG1 . THR C 1 303 ? 16.683  2.509   -7.104  1.00 26.02  ? 303 THR C OG1 1 
ATOM   6828  C  CG2 . THR C 1 303 ? 15.503  4.426   -6.608  1.00 27.19  ? 303 THR C CG2 1 
ATOM   6829  N  N   . PRO C 1 304 ? 19.142  4.767   -9.860  1.00 25.44  ? 304 PRO C N   1 
ATOM   6830  C  CA  . PRO C 1 304 ? 20.417  4.365   -10.434 1.00 26.66  ? 304 PRO C CA  1 
ATOM   6831  C  C   . PRO C 1 304 ? 21.433  3.870   -9.424  1.00 30.39  ? 304 PRO C C   1 
ATOM   6832  O  O   . PRO C 1 304 ? 21.289  4.081   -8.214  1.00 35.73  ? 304 PRO C O   1 
ATOM   6833  C  CB  . PRO C 1 304 ? 20.938  5.643   -11.078 1.00 27.73  ? 304 PRO C CB  1 
ATOM   6834  C  CG  . PRO C 1 304 ? 19.745  6.535   -11.248 1.00 29.16  ? 304 PRO C CG  1 
ATOM   6835  C  CD  . PRO C 1 304 ? 18.837  6.183   -10.101 1.00 28.61  ? 304 PRO C CD  1 
ATOM   6836  N  N   . ALA C 1 305 ? 22.481  3.221   -9.948  1.00 31.03  ? 305 ALA C N   1 
ATOM   6837  C  CA  . ALA C 1 305 ? 23.632  2.939   -9.121  1.00 28.37  ? 305 ALA C CA  1 
ATOM   6838  C  C   . ALA C 1 305 ? 24.241  4.272   -8.695  1.00 27.26  ? 305 ALA C C   1 
ATOM   6839  O  O   . ALA C 1 305 ? 24.052  5.276   -9.358  1.00 26.80  ? 305 ALA C O   1 
ATOM   6840  C  CB  . ALA C 1 305 ? 24.589  2.084   -9.873  1.00 29.42  ? 305 ALA C CB  1 
ATOM   6841  N  N   . ALA C 1 306 ? 24.912  4.274   -7.541  1.00 29.57  ? 306 ALA C N   1 
ATOM   6842  C  CA  . ALA C 1 306 ? 25.473  5.479   -6.953  1.00 29.68  ? 306 ALA C CA  1 
ATOM   6843  C  C   . ALA C 1 306 ? 26.513  6.104   -7.878  1.00 35.67  ? 306 ALA C C   1 
ATOM   6844  O  O   . ALA C 1 306 ? 26.573  7.323   -7.965  1.00 35.69  ? 306 ALA C O   1 
ATOM   6845  C  CB  . ALA C 1 306 ? 26.033  5.179   -5.598  1.00 31.46  ? 306 ALA C CB  1 
ATOM   6846  N  N   . ASP C 1 307 ? 27.279  5.293   -8.627  1.00 40.07  ? 307 ASP C N   1 
ATOM   6847  C  CA  . ASP C 1 307 ? 28.330  5.838   -9.477  1.00 44.78  ? 307 ASP C CA  1 
ATOM   6848  C  C   . ASP C 1 307 ? 27.693  6.530   -10.666 1.00 41.07  ? 307 ASP C C   1 
ATOM   6849  O  O   . ASP C 1 307 ? 28.261  7.517   -11.117 1.00 44.35  ? 307 ASP C O   1 
ATOM   6850  C  CB  . ASP C 1 307 ? 29.434  4.861   -9.872  1.00 52.26  ? 307 ASP C CB  1 
ATOM   6851  C  CG  . ASP C 1 307 ? 29.015  3.407   -10.019 1.00 62.90  ? 307 ASP C CG  1 
ATOM   6852  O  OD1 . ASP C 1 307 ? 28.292  3.067   -10.996 1.00 63.53  ? 307 ASP C OD1 1 
ATOM   6853  O  OD2 . ASP C 1 307 ? 29.386  2.641   -9.123  1.00 83.27  ? 307 ASP C OD2 1 
ATOM   6854  N  N   . PHE C 1 308 ? 26.516  6.066   -11.119 1.00 34.68  ? 308 PHE C N   1 
ATOM   6855  C  CA  . PHE C 1 308 ? 25.822  6.787   -12.170 1.00 34.57  ? 308 PHE C CA  1 
ATOM   6856  C  C   . PHE C 1 308 ? 25.658  8.259   -11.772 1.00 34.34  ? 308 PHE C C   1 
ATOM   6857  O  O   . PHE C 1 308 ? 25.954  9.166   -12.559 1.00 37.29  ? 308 PHE C O   1 
ATOM   6858  C  CB  . PHE C 1 308 ? 24.510  6.109   -12.557 1.00 33.40  ? 308 PHE C CB  1 
ATOM   6859  C  CG  . PHE C 1 308 ? 23.729  6.882   -13.612 1.00 36.24  ? 308 PHE C CG  1 
ATOM   6860  C  CD1 . PHE C 1 308 ? 22.919  7.963   -13.276 1.00 41.30  ? 308 PHE C CD1 1 
ATOM   6861  C  CD2 . PHE C 1 308 ? 23.800  6.535   -14.957 1.00 42.83  ? 308 PHE C CD2 1 
ATOM   6862  C  CE1 . PHE C 1 308 ? 22.208  8.662   -14.251 1.00 42.67  ? 308 PHE C CE1 1 
ATOM   6863  C  CE2 . PHE C 1 308 ? 23.062  7.222   -15.925 1.00 40.70  ? 308 PHE C CE2 1 
ATOM   6864  C  CZ  . PHE C 1 308 ? 22.249  8.267   -15.566 1.00 40.81  ? 308 PHE C CZ  1 
ATOM   6865  N  N   . LEU C 1 309 ? 25.201  8.521   -10.546 1.00 32.87  ? 309 LEU C N   1 
ATOM   6866  C  CA  . LEU C 1 309 ? 24.865  9.883   -10.156 1.00 35.34  ? 309 LEU C CA  1 
ATOM   6867  C  C   . LEU C 1 309 ? 26.134  10.722  -9.992  1.00 38.19  ? 309 LEU C C   1 
ATOM   6868  O  O   . LEU C 1 309 ? 26.151  11.874  -10.423 1.00 40.63  ? 309 LEU C O   1 
ATOM   6869  C  CB  . LEU C 1 309 ? 24.001  9.846   -8.894  1.00 39.28  ? 309 LEU C CB  1 
ATOM   6870  C  CG  . LEU C 1 309 ? 22.634  9.140   -8.982  1.00 33.68  ? 309 LEU C CG  1 
ATOM   6871  C  CD1 . LEU C 1 309 ? 22.111  8.784   -7.612  1.00 30.89  ? 309 LEU C CD1 1 
ATOM   6872  C  CD2 . LEU C 1 309 ? 21.682  10.056  -9.695  1.00 32.96  ? 309 LEU C CD2 1 
ATOM   6873  N  N   . GLU C 1 310 ? 27.180  10.130  -9.383  1.00 44.49  ? 310 GLU C N   1 
ATOM   6874  C  CA  . GLU C 1 310 ? 28.491  10.743  -9.179  1.00 52.53  ? 310 GLU C CA  1 
ATOM   6875  C  C   . GLU C 1 310 ? 28.998  11.404  -10.461 1.00 53.38  ? 310 GLU C C   1 
ATOM   6876  O  O   . GLU C 1 310 ? 29.410  12.557  -10.416 1.00 61.51  ? 310 GLU C O   1 
ATOM   6877  C  CB  . GLU C 1 310 ? 29.511  9.724   -8.662  1.00 58.17  ? 310 GLU C CB  1 
ATOM   6878  C  CG  . GLU C 1 310 ? 30.790  10.351  -8.110  1.00 64.36  ? 310 GLU C CG  1 
ATOM   6879  C  CD  . GLU C 1 310 ? 31.360  9.568   -6.936  1.00 72.93  ? 310 GLU C CD  1 
ATOM   6880  O  OE1 . GLU C 1 310 ? 32.260  8.699   -7.097  1.00 90.17  ? 310 GLU C OE1 1 
ATOM   6881  O  OE2 . GLU C 1 310 ? 30.893  9.853   -5.817  1.00 65.57  ? 310 GLU C OE2 1 
ATOM   6882  N  N   . ASP C 1 311 ? 28.903  10.709  -11.601 1.00 58.17  ? 311 ASP C N   1 
ATOM   6883  C  CA  . ASP C 1 311 ? 29.527  11.160  -12.839 1.00 64.23  ? 311 ASP C CA  1 
ATOM   6884  C  C   . ASP C 1 311 ? 28.570  11.996  -13.691 1.00 66.48  ? 311 ASP C C   1 
ATOM   6885  O  O   . ASP C 1 311 ? 28.180  11.516  -14.748 1.00 81.03  ? 311 ASP C O   1 
ATOM   6886  C  CB  . ASP C 1 311 ? 30.048  9.973   -13.644 1.00 65.92  ? 311 ASP C CB  1 
ATOM   6887  C  CG  . ASP C 1 311 ? 30.856  8.940   -12.859 1.00 79.20  ? 311 ASP C CG  1 
ATOM   6888  O  OD1 . ASP C 1 311 ? 31.720  9.343   -12.018 1.00 83.14  ? 311 ASP C OD1 1 
ATOM   6889  O  OD2 . ASP C 1 311 ? 30.632  7.723   -13.103 1.00 72.00  ? 311 ASP C OD2 1 
ATOM   6890  N  N   . LEU C 1 312 ? 28.265  13.254  -13.297 1.00 71.83  ? 312 LEU C N   1 
ATOM   6891  C  CA  . LEU C 1 312 ? 27.392  14.121  -14.094 1.00 80.91  ? 312 LEU C CA  1 
ATOM   6892  C  C   . LEU C 1 312 ? 27.997  15.530  -14.329 1.00 68.74  ? 312 LEU C C   1 
ATOM   6893  O  O   . LEU C 1 312 ? 29.157  15.786  -13.932 1.00 66.72  ? 312 LEU C O   1 
ATOM   6894  C  CB  . LEU C 1 312 ? 25.985  14.219  -13.483 1.00 83.95  ? 312 LEU C CB  1 
ATOM   6895  C  CG  . LEU C 1 312 ? 25.107  12.953  -13.493 1.00 72.09  ? 312 LEU C CG  1 
ATOM   6896  C  CD1 . LEU C 1 312 ? 23.702  13.288  -13.050 1.00 64.22  ? 312 LEU C CD1 1 
ATOM   6897  C  CD2 . LEU C 1 312 ? 25.013  12.212  -14.816 1.00 69.25  ? 312 LEU C CD2 1 
ATOM   6898  N  N   . GLU D 1 7   ? 41.560  -12.323 -0.796  1.00 108.08 ? 7   GLU D N   1 
ATOM   6899  C  CA  . GLU D 1 7   ? 42.807  -11.716 -0.258  1.00 107.09 ? 7   GLU D CA  1 
ATOM   6900  C  C   . GLU D 1 7   ? 43.556  -12.755 0.602   1.00 104.97 ? 7   GLU D C   1 
ATOM   6901  O  O   . GLU D 1 7   ? 43.125  -13.910 0.788   1.00 81.94  ? 7   GLU D O   1 
ATOM   6902  C  CB  . GLU D 1 7   ? 42.454  -10.365 0.396   1.00 81.60  ? 7   GLU D CB  1 
ATOM   6903  N  N   . PRO D 1 8   ? 44.797  -12.401 1.016   1.00 92.67  ? 8   PRO D N   1 
ATOM   6904  C  CA  . PRO D 1 8   ? 45.307  -12.710 2.357   1.00 82.26  ? 8   PRO D CA  1 
ATOM   6905  C  C   . PRO D 1 8   ? 44.448  -11.874 3.312   1.00 66.35  ? 8   PRO D C   1 
ATOM   6906  O  O   . PRO D 1 8   ? 43.895  -10.872 2.856   1.00 48.30  ? 8   PRO D O   1 
ATOM   6907  C  CB  . PRO D 1 8   ? 46.790  -12.241 2.296   1.00 79.03  ? 8   PRO D CB  1 
ATOM   6908  C  CG  . PRO D 1 8   ? 47.102  -12.041 0.835   1.00 73.27  ? 8   PRO D CG  1 
ATOM   6909  C  CD  . PRO D 1 8   ? 45.777  -11.660 0.211   1.00 78.26  ? 8   PRO D CD  1 
ATOM   6910  N  N   . GLU D 1 9   ? 44.366  -12.260 4.614   1.00 62.06  ? 9   GLU D N   1 
ATOM   6911  C  CA  . GLU D 1 9   ? 43.689  -11.498 5.671   1.00 58.11  ? 9   GLU D CA  1 
ATOM   6912  C  C   . GLU D 1 9   ? 44.561  -10.258 5.982   1.00 52.72  ? 9   GLU D C   1 
ATOM   6913  O  O   . GLU D 1 9   ? 45.725  -10.366 6.393   1.00 51.94  ? 9   GLU D O   1 
ATOM   6914  C  CB  . GLU D 1 9   ? 43.337  -12.369 6.918   1.00 54.75  ? 9   GLU D CB  1 
ATOM   6915  C  CG  . GLU D 1 9   ? 41.869  -12.578 7.304   1.00 43.72  ? 9   GLU D CG  1 
ATOM   6916  N  N   . PRO D 1 10  ? 44.085  -9.011  5.745   1.00 45.09  ? 10  PRO D N   1 
ATOM   6917  C  CA  . PRO D 1 10  ? 44.780  -7.819  6.237   1.00 50.46  ? 10  PRO D CA  1 
ATOM   6918  C  C   . PRO D 1 10  ? 44.584  -7.635  7.743   1.00 48.90  ? 10  PRO D C   1 
ATOM   6919  O  O   . PRO D 1 10  ? 43.690  -8.227  8.344   1.00 40.63  ? 10  PRO D O   1 
ATOM   6920  C  CB  . PRO D 1 10  ? 44.131  -6.670  5.452   1.00 47.45  ? 10  PRO D CB  1 
ATOM   6921  C  CG  . PRO D 1 10  ? 42.734  -7.170  5.219   1.00 45.01  ? 10  PRO D CG  1 
ATOM   6922  C  CD  . PRO D 1 10  ? 42.891  -8.651  4.967   1.00 48.15  ? 10  PRO D CD  1 
ATOM   6923  N  N   . GLN D 1 11  ? 45.425  -6.782  8.340   1.00 45.02  ? 11  GLN D N   1 
ATOM   6924  C  CA  . GLN D 1 11  ? 45.181  -6.342  9.698   1.00 35.21  ? 11  GLN D CA  1 
ATOM   6925  C  C   . GLN D 1 11  ? 43.962  -5.431  9.654   1.00 32.34  ? 11  GLN D C   1 
ATOM   6926  O  O   . GLN D 1 11  ? 43.459  -5.131  8.577   1.00 29.23  ? 11  GLN D O   1 
ATOM   6927  C  CB  . GLN D 1 11  ? 46.405  -5.638  10.282  1.00 34.68  ? 11  GLN D CB  1 
ATOM   6928  C  CG  . GLN D 1 11  ? 47.636  -6.518  10.490  1.00 29.00  ? 11  GLN D CG  1 
ATOM   6929  C  CD  . GLN D 1 11  ? 48.722  -5.710  11.152  1.00 28.14  ? 11  GLN D CD  1 
ATOM   6930  O  OE1 . GLN D 1 11  ? 48.595  -5.231  12.300  1.00 26.22  ? 11  GLN D OE1 1 
ATOM   6931  N  NE2 . GLN D 1 11  ? 49.779  -5.502  10.385  1.00 29.87  ? 11  GLN D NE2 1 
ATOM   6932  N  N   . MET D 1 12  ? 43.518  -4.965  10.821  1.00 34.31  ? 12  MET D N   1 
ATOM   6933  C  CA  . MET D 1 12  ? 42.276  -4.224  10.939  1.00 37.33  ? 12  MET D CA  1 
ATOM   6934  C  C   . MET D 1 12  ? 42.506  -2.762  10.563  1.00 35.03  ? 12  MET D C   1 
ATOM   6935  O  O   . MET D 1 12  ? 42.194  -1.840  11.336  1.00 38.08  ? 12  MET D O   1 
ATOM   6936  C  CB  . MET D 1 12  ? 41.739  -4.263  12.381  1.00 47.99  ? 12  MET D CB  1 
ATOM   6937  C  CG  . MET D 1 12  ? 40.246  -3.904  12.521  1.00 49.38  ? 12  MET D CG  1 
ATOM   6938  S  SD  . MET D 1 12  ? 39.245  -5.237  11.823  1.00 58.60  ? 12  MET D SD  1 
ATOM   6939  C  CE  . MET D 1 12  ? 40.178  -6.789  11.765  1.00 55.31  ? 12  MET D CE  1 
ATOM   6940  N  N   . VAL D 1 13  ? 42.982  -2.526  9.342   1.00 30.91  ? 13  VAL D N   1 
ATOM   6941  C  CA  . VAL D 1 13  ? 43.236  -1.154  8.942   1.00 33.90  ? 13  VAL D CA  1 
ATOM   6942  C  C   . VAL D 1 13  ? 41.903  -0.420  8.806   1.00 35.39  ? 13  VAL D C   1 
ATOM   6943  O  O   . VAL D 1 13  ? 41.787  0.678   9.350   1.00 29.92  ? 13  VAL D O   1 
ATOM   6944  C  CB  . VAL D 1 13  ? 44.074  -1.146  7.659   1.00 34.05  ? 13  VAL D CB  1 
ATOM   6945  C  CG1 . VAL D 1 13  ? 44.190  0.239   7.071   1.00 36.70  ? 13  VAL D CG1 1 
ATOM   6946  C  CG2 . VAL D 1 13  ? 45.472  -1.692  7.929   1.00 38.63  ? 13  VAL D CG2 1 
ATOM   6947  N  N   . LEU D 1 14  ? 40.919  -1.056  8.136   1.00 40.34  ? 14  LEU D N   1 
ATOM   6948  C  CA  . LEU D 1 14  ? 39.558  -0.543  8.044   1.00 47.36  ? 14  LEU D CA  1 
ATOM   6949  C  C   . LEU D 1 14  ? 38.807  -0.856  9.326   1.00 50.79  ? 14  LEU D C   1 
ATOM   6950  O  O   . LEU D 1 14  ? 38.265  -1.930  9.469   1.00 62.91  ? 14  LEU D O   1 
ATOM   6951  C  CB  . LEU D 1 14  ? 38.863  -1.191  6.852   1.00 48.17  ? 14  LEU D CB  1 
ATOM   6952  C  CG  . LEU D 1 14  ? 39.683  -1.169  5.561   1.00 56.08  ? 14  LEU D CG  1 
ATOM   6953  C  CD1 . LEU D 1 14  ? 39.292  -2.186  4.496   1.00 57.23  ? 14  LEU D CD1 1 
ATOM   6954  C  CD2 . LEU D 1 14  ? 39.586  0.237   5.014   1.00 56.51  ? 14  LEU D CD2 1 
ATOM   6955  N  N   . SER D 1 15  ? 38.822  0.039   10.292  1.00 51.00  ? 15  SER D N   1 
ATOM   6956  C  CA  . SER D 1 15  ? 38.145  -0.244  11.543  1.00 54.14  ? 15  SER D CA  1 
ATOM   6957  C  C   . SER D 1 15  ? 36.867  0.580   11.546  1.00 48.19  ? 15  SER D C   1 
ATOM   6958  O  O   . SER D 1 15  ? 36.827  1.632   10.933  1.00 46.77  ? 15  SER D O   1 
ATOM   6959  C  CB  . SER D 1 15  ? 39.071  0.023   12.731  1.00 62.08  ? 15  SER D CB  1 
ATOM   6960  O  OG  . SER D 1 15  ? 38.425  0.469   13.915  1.00 66.49  ? 15  SER D OG  1 
ATOM   6961  N  N   . PRO D 1 16  ? 35.764  0.097   12.149  1.00 57.32  ? 16  PRO D N   1 
ATOM   6962  C  CA  . PRO D 1 16  ? 34.663  0.981   12.541  1.00 58.04  ? 16  PRO D CA  1 
ATOM   6963  C  C   . PRO D 1 16  ? 35.163  2.260   13.208  1.00 54.96  ? 16  PRO D C   1 
ATOM   6964  O  O   . PRO D 1 16  ? 36.326  2.338   13.611  1.00 57.39  ? 16  PRO D O   1 
ATOM   6965  C  CB  . PRO D 1 16  ? 33.854  0.119   13.561  1.00 65.18  ? 16  PRO D CB  1 
ATOM   6966  C  CG  . PRO D 1 16  ? 34.663  -1.162  13.773  1.00 61.92  ? 16  PRO D CG  1 
ATOM   6967  C  CD  . PRO D 1 16  ? 35.516  -1.314  12.507  1.00 60.30  ? 16  PRO D CD  1 
ATOM   6968  N  N   . LEU D 1 17  ? 34.272  3.246   13.328  1.00 46.72  ? 17  LEU D N   1 
ATOM   6969  C  CA  . LEU D 1 17  ? 34.514  4.405   14.174  1.00 43.47  ? 17  LEU D CA  1 
ATOM   6970  C  C   . LEU D 1 17  ? 34.684  3.857   15.601  1.00 39.57  ? 17  LEU D C   1 
ATOM   6971  O  O   . LEU D 1 17  ? 33.940  3.000   16.070  1.00 34.22  ? 17  LEU D O   1 
ATOM   6972  C  CB  . LEU D 1 17  ? 33.427  5.488   14.025  1.00 38.06  ? 17  LEU D CB  1 
ATOM   6973  N  N   . THR D 1 18  ? 35.761  4.308   16.265  1.00 35.44  ? 18  THR D N   1 
ATOM   6974  C  CA  . THR D 1 18  ? 36.100  3.972   17.644  1.00 29.39  ? 18  THR D CA  1 
ATOM   6975  C  C   . THR D 1 18  ? 36.380  5.293   18.318  1.00 25.17  ? 18  THR D C   1 
ATOM   6976  O  O   . THR D 1 18  ? 36.747  6.238   17.635  1.00 28.73  ? 18  THR D O   1 
ATOM   6977  C  CB  . THR D 1 18  ? 37.339  3.079   17.686  1.00 29.52  ? 18  THR D CB  1 
ATOM   6978  O  OG1 . THR D 1 18  ? 38.356  3.705   16.904  1.00 29.06  ? 18  THR D OG1 1 
ATOM   6979  C  CG2 . THR D 1 18  ? 37.106  1.684   17.138  1.00 30.84  ? 18  THR D CG2 1 
ATOM   6980  N  N   . SER D 1 19  ? 36.234  5.381   19.631  1.00 25.31  ? 19  SER D N   1 
ATOM   6981  C  CA  . SER D 1 19  ? 36.314  6.697   20.257  1.00 27.51  ? 19  SER D CA  1 
ATOM   6982  C  C   . SER D 1 19  ? 37.553  6.846   21.126  1.00 26.03  ? 19  SER D C   1 
ATOM   6983  O  O   . SER D 1 19  ? 37.786  7.920   21.690  1.00 26.33  ? 19  SER D O   1 
ATOM   6984  C  CB  . SER D 1 19  ? 35.080  6.997   21.028  1.00 31.22  ? 19  SER D CB  1 
ATOM   6985  O  OG  . SER D 1 19  ? 34.527  5.744   21.365  1.00 39.44  ? 19  SER D OG  1 
ATOM   6986  N  N   . ALA D 1 20  ? 38.375  5.793   21.217  1.00 24.81  ? 20  ALA D N   1 
ATOM   6987  C  CA  . ALA D 1 20  ? 39.622  5.892   21.965  1.00 23.52  ? 20  ALA D CA  1 
ATOM   6988  C  C   . ALA D 1 20  ? 40.738  5.199   21.189  1.00 24.12  ? 20  ALA D C   1 
ATOM   6989  O  O   . ALA D 1 20  ? 40.491  4.245   20.455  1.00 23.62  ? 20  ALA D O   1 
ATOM   6990  C  CB  . ALA D 1 20  ? 39.471  5.294   23.345  1.00 21.31  ? 20  ALA D CB  1 
ATOM   6991  N  N   . ALA D 1 21  ? 41.960  5.684   21.389  1.00 24.90  ? 21  ALA D N   1 
ATOM   6992  C  CA  . ALA D 1 21  ? 43.117  5.104   20.754  1.00 26.88  ? 21  ALA D CA  1 
ATOM   6993  C  C   . ALA D 1 21  ? 44.345  5.302   21.621  1.00 21.47  ? 21  ALA D C   1 
ATOM   6994  O  O   . ALA D 1 21  ? 44.494  6.301   22.321  1.00 19.90  ? 21  ALA D O   1 
ATOM   6995  C  CB  . ALA D 1 21  ? 43.291  5.771   19.402  1.00 30.84  ? 21  ALA D CB  1 
ATOM   6996  N  N   . ILE D 1 22  ? 45.249  4.340   21.486  1.00 22.96  ? 22  ILE D N   1 
ATOM   6997  C  CA  . ILE D 1 22  ? 46.622  4.537   21.927  1.00 25.85  ? 22  ILE D CA  1 
ATOM   6998  C  C   . ILE D 1 22  ? 47.539  4.349   20.715  1.00 23.80  ? 22  ILE D C   1 
ATOM   6999  O  O   . ILE D 1 22  ? 47.401  3.389   19.956  1.00 21.83  ? 22  ILE D O   1 
ATOM   7000  C  CB  . ILE D 1 22  ? 46.992  3.589   23.088  1.00 26.27  ? 22  ILE D CB  1 
ATOM   7001  C  CG1 . ILE D 1 22  ? 46.376  4.036   24.370  1.00 26.27  ? 22  ILE D CG1 1 
ATOM   7002  C  CG2 . ILE D 1 22  ? 48.506  3.495   23.227  1.00 28.56  ? 22  ILE D CG2 1 
ATOM   7003  C  CD1 . ILE D 1 22  ? 46.526  3.035   25.504  1.00 28.22  ? 22  ILE D CD1 1 
ATOM   7004  N  N   . PHE D 1 23  ? 48.422  5.334   20.538  1.00 21.68  ? 23  PHE D N   1 
ATOM   7005  C  CA  . PHE D 1 23  ? 49.495  5.275   19.564  1.00 20.62  ? 23  PHE D CA  1 
ATOM   7006  C  C   . PHE D 1 23  ? 50.809  5.087   20.318  1.00 22.38  ? 23  PHE D C   1 
ATOM   7007  O  O   . PHE D 1 23  ? 51.207  5.923   21.136  1.00 23.29  ? 23  PHE D O   1 
ATOM   7008  C  CB  . PHE D 1 23  ? 49.604  6.578   18.782  1.00 20.04  ? 23  PHE D CB  1 
ATOM   7009  C  CG  . PHE D 1 23  ? 48.332  6.922   18.045  1.00 21.76  ? 23  PHE D CG  1 
ATOM   7010  C  CD1 . PHE D 1 23  ? 48.072  6.420   16.773  1.00 21.22  ? 23  PHE D CD1 1 
ATOM   7011  C  CD2 . PHE D 1 23  ? 47.389  7.740   18.652  1.00 23.49  ? 23  PHE D CD2 1 
ATOM   7012  C  CE1 . PHE D 1 23  ? 46.897  6.733   16.117  1.00 21.62  ? 23  PHE D CE1 1 
ATOM   7013  C  CE2 . PHE D 1 23  ? 46.235  8.075   17.987  1.00 23.65  ? 23  PHE D CE2 1 
ATOM   7014  C  CZ  . PHE D 1 23  ? 45.989  7.560   16.724  1.00 21.92  ? 23  PHE D CZ  1 
ATOM   7015  N  N   . LEU D 1 24  ? 51.490  3.998   19.999  1.00 23.46  ? 24  LEU D N   1 
ATOM   7016  C  CA  . LEU D 1 24  ? 52.746  3.658   20.632  1.00 27.05  ? 24  LEU D CA  1 
ATOM   7017  C  C   . LEU D 1 24  ? 53.816  3.496   19.549  1.00 27.92  ? 24  LEU D C   1 
ATOM   7018  O  O   . LEU D 1 24  ? 53.643  2.691   18.617  1.00 23.07  ? 24  LEU D O   1 
ATOM   7019  C  CB  . LEU D 1 24  ? 52.393  2.340   21.308  1.00 30.51  ? 24  LEU D CB  1 
ATOM   7020  C  CG  . LEU D 1 24  ? 53.281  1.910   22.457  1.00 37.31  ? 24  LEU D CG  1 
ATOM   7021  C  CD1 . LEU D 1 24  ? 53.421  3.000   23.479  1.00 42.57  ? 24  LEU D CD1 1 
ATOM   7022  C  CD2 . LEU D 1 24  ? 52.619  0.670   23.005  1.00 40.33  ? 24  LEU D CD2 1 
ATOM   7023  N  N   . VAL D 1 25  ? 54.889  4.299   19.665  1.00 24.48  ? 25  VAL D N   1 
ATOM   7024  C  CA  . VAL D 1 25  ? 56.000  4.230   18.735  1.00 24.51  ? 25  VAL D CA  1 
ATOM   7025  C  C   . VAL D 1 25  ? 57.258  3.907   19.514  1.00 23.57  ? 25  VAL D C   1 
ATOM   7026  O  O   . VAL D 1 25  ? 57.557  4.567   20.498  1.00 22.12  ? 25  VAL D O   1 
ATOM   7027  C  CB  . VAL D 1 25  ? 56.213  5.535   17.969  1.00 25.81  ? 25  VAL D CB  1 
ATOM   7028  C  CG1 . VAL D 1 25  ? 57.408  5.405   17.034  1.00 27.94  ? 25  VAL D CG1 1 
ATOM   7029  C  CG2 . VAL D 1 25  ? 54.979  5.890   17.180  1.00 26.37  ? 25  VAL D CG2 1 
ATOM   7030  N  N   . VAL D 1 26  ? 57.957  2.870   19.064  1.00 22.89  ? 26  VAL D N   1 
ATOM   7031  C  CA  . VAL D 1 26  ? 59.154  2.433   19.749  1.00 25.23  ? 26  VAL D CA  1 
ATOM   7032  C  C   . VAL D 1 26  ? 60.284  2.221   18.742  1.00 24.78  ? 26  VAL D C   1 
ATOM   7033  O  O   . VAL D 1 26  ? 60.059  2.046   17.537  1.00 23.20  ? 26  VAL D O   1 
ATOM   7034  C  CB  . VAL D 1 26  ? 58.878  1.145   20.561  1.00 26.55  ? 26  VAL D CB  1 
ATOM   7035  C  CG1 . VAL D 1 26  ? 57.768  1.392   21.574  1.00 27.41  ? 26  VAL D CG1 1 
ATOM   7036  C  CG2 . VAL D 1 26  ? 58.594  -0.092  19.687  1.00 25.02  ? 26  VAL D CG2 1 
ATOM   7037  N  N   . THR D 1 27  ? 61.507  2.238   19.290  1.00 29.03  ? 27  THR D N   1 
ATOM   7038  C  CA  . THR D 1 27  ? 62.691  1.790   18.578  1.00 30.18  ? 27  THR D CA  1 
ATOM   7039  C  C   . THR D 1 27  ? 63.183  0.510   19.232  1.00 28.49  ? 27  THR D C   1 
ATOM   7040  O  O   . THR D 1 27  ? 63.045  0.322   20.430  1.00 23.91  ? 27  THR D O   1 
ATOM   7041  C  CB  . THR D 1 27  ? 63.764  2.881   18.554  1.00 27.65  ? 27  THR D CB  1 
ATOM   7042  O  OG1 . THR D 1 27  ? 64.024  3.241   19.916  1.00 27.35  ? 27  THR D OG1 1 
ATOM   7043  C  CG2 . THR D 1 27  ? 63.309  4.060   17.712  1.00 27.85  ? 27  THR D CG2 1 
ATOM   7044  N  N   . ILE D 1 28  ? 63.765  -0.339  18.398  1.00 26.70  ? 28  ILE D N   1 
ATOM   7045  C  CA  . ILE D 1 28  ? 64.323  -1.599  18.812  1.00 28.74  ? 28  ILE D CA  1 
ATOM   7046  C  C   . ILE D 1 28  ? 65.784  -1.422  19.248  1.00 32.48  ? 28  ILE D C   1 
ATOM   7047  O  O   . ILE D 1 28  ? 66.620  -1.005  18.477  1.00 34.64  ? 28  ILE D O   1 
ATOM   7048  C  CB  . ILE D 1 28  ? 64.217  -2.601  17.664  1.00 27.65  ? 28  ILE D CB  1 
ATOM   7049  C  CG1 . ILE D 1 28  ? 62.803  -2.673  17.103  1.00 28.99  ? 28  ILE D CG1 1 
ATOM   7050  C  CG2 . ILE D 1 28  ? 64.704  -3.973  18.136  1.00 32.76  ? 28  ILE D CG2 1 
ATOM   7051  C  CD1 . ILE D 1 28  ? 62.709  -3.442  15.791  1.00 32.46  ? 28  ILE D CD1 1 
ATOM   7052  N  N   . ASP D 1 29  ? 66.106  -1.805  20.480  1.00 34.29  ? 29  ASP D N   1 
ATOM   7053  C  CA  . ASP D 1 29  ? 67.461  -1.755  20.989  1.00 33.62  ? 29  ASP D CA  1 
ATOM   7054  C  C   . ASP D 1 29  ? 68.288  -2.870  20.336  1.00 37.38  ? 29  ASP D C   1 
ATOM   7055  O  O   . ASP D 1 29  ? 67.739  -3.813  19.752  1.00 33.07  ? 29  ASP D O   1 
ATOM   7056  C  CB  . ASP D 1 29  ? 67.457  -1.900  22.498  1.00 36.43  ? 29  ASP D CB  1 
ATOM   7057  C  CG  . ASP D 1 29  ? 66.699  -0.854  23.306  1.00 42.41  ? 29  ASP D CG  1 
ATOM   7058  O  OD1 . ASP D 1 29  ? 66.180  0.117   22.684  1.00 38.43  ? 29  ASP D OD1 1 
ATOM   7059  O  OD2 . ASP D 1 29  ? 66.649  -1.014  24.564  1.00 48.45  ? 29  ASP D OD2 1 
ATOM   7060  N  N   . SER D 1 30  ? 69.633  -2.750  20.395  1.00 43.96  ? 30  SER D N   1 
ATOM   7061  C  CA  . SER D 1 30  ? 70.497  -3.808  19.879  1.00 43.79  ? 30  SER D CA  1 
ATOM   7062  C  C   . SER D 1 30  ? 70.229  -5.062  20.676  1.00 38.83  ? 30  SER D C   1 
ATOM   7063  O  O   . SER D 1 30  ? 70.192  -5.004  21.894  1.00 34.13  ? 30  SER D O   1 
ATOM   7064  C  CB  . SER D 1 30  ? 71.950  -3.483  19.953  1.00 46.16  ? 30  SER D CB  1 
ATOM   7065  O  OG  . SER D 1 30  ? 72.158  -2.312  19.184  1.00 55.57  ? 30  SER D OG  1 
ATOM   7066  N  N   . GLY D 1 31  ? 70.049  -6.177  19.971  1.00 38.74  ? 31  GLY D N   1 
ATOM   7067  C  CA  . GLY D 1 31  ? 69.814  -7.445  20.635  1.00 35.43  ? 31  GLY D CA  1 
ATOM   7068  C  C   . GLY D 1 31  ? 68.322  -7.700  20.797  1.00 33.74  ? 31  GLY D C   1 
ATOM   7069  O  O   . GLY D 1 31  ? 67.927  -8.830  21.059  1.00 33.99  ? 31  GLY D O   1 
ATOM   7070  N  N   . GLY D 1 32  ? 67.504  -6.689  20.506  1.00 35.05  ? 32  GLY D N   1 
ATOM   7071  C  CA  . GLY D 1 32  ? 66.073  -6.774  20.710  1.00 38.43  ? 32  GLY D CA  1 
ATOM   7072  C  C   . GLY D 1 32  ? 65.314  -7.577  19.648  1.00 37.57  ? 32  GLY D C   1 
ATOM   7073  O  O   . GLY D 1 32  ? 64.134  -7.902  19.824  1.00 37.94  ? 32  GLY D O   1 
ATOM   7074  N  N   . GLU D 1 33  ? 65.983  -7.911  18.550  1.00 36.95  ? 33  GLU D N   1 
ATOM   7075  C  CA  . GLU D 1 33  ? 65.307  -8.357  17.341  1.00 38.30  ? 33  GLU D CA  1 
ATOM   7076  C  C   . GLU D 1 33  ? 64.457  -9.613  17.591  1.00 36.46  ? 33  GLU D C   1 
ATOM   7077  O  O   . GLU D 1 33  ? 63.380  -9.795  17.021  1.00 34.77  ? 33  GLU D O   1 
ATOM   7078  C  CB  . GLU D 1 33  ? 66.347  -8.566  16.223  1.00 38.91  ? 33  GLU D CB  1 
ATOM   7079  C  CG  . GLU D 1 33  ? 67.057  -7.309  15.703  1.00 39.82  ? 33  GLU D CG  1 
ATOM   7080  C  CD  . GLU D 1 33  ? 68.185  -6.709  16.546  1.00 46.53  ? 33  GLU D CD  1 
ATOM   7081  O  OE1 . GLU D 1 33  ? 68.631  -7.368  17.534  1.00 40.20  ? 33  GLU D OE1 1 
ATOM   7082  O  OE2 . GLU D 1 33  ? 68.629  -5.566  16.242  1.00 49.13  ? 33  GLU D OE2 1 
ATOM   7083  N  N   . ASP D 1 34  ? 64.984  -10.534 18.391  1.00 39.51  ? 34  ASP D N   1 
ATOM   7084  C  CA  . ASP D 1 34  ? 64.318  -11.811 18.577  1.00 42.85  ? 34  ASP D CA  1 
ATOM   7085  C  C   . ASP D 1 34  ? 63.080  -11.646 19.444  1.00 33.41  ? 34  ASP D C   1 
ATOM   7086  O  O   . ASP D 1 34  ? 62.053  -12.223 19.142  1.00 28.10  ? 34  ASP D O   1 
ATOM   7087  C  CB  . ASP D 1 34  ? 65.247  -12.848 19.178  1.00 51.81  ? 34  ASP D CB  1 
ATOM   7088  C  CG  . ASP D 1 34  ? 66.154  -13.511 18.158  1.00 55.75  ? 34  ASP D CG  1 
ATOM   7089  O  OD1 . ASP D 1 34  ? 65.622  -13.852 17.050  1.00 56.90  ? 34  ASP D OD1 1 
ATOM   7090  O  OD2 . ASP D 1 34  ? 67.349  -13.692 18.509  1.00 51.67  ? 34  ASP D OD2 1 
ATOM   7091  N  N   . THR D 1 35  ? 63.187  -10.870 20.511  1.00 29.35  ? 35  THR D N   1 
ATOM   7092  C  CA  . THR D 1 35  ? 62.014  -10.602 21.330  1.00 34.11  ? 35  THR D CA  1 
ATOM   7093  C  C   . THR D 1 35  ? 60.895  -10.036 20.465  1.00 30.65  ? 35  THR D C   1 
ATOM   7094  O  O   . THR D 1 35  ? 59.755  -10.456 20.603  1.00 25.63  ? 35  THR D O   1 
ATOM   7095  C  CB  . THR D 1 35  ? 62.363  -9.596  22.421  1.00 36.75  ? 35  THR D CB  1 
ATOM   7096  O  OG1 . THR D 1 35  ? 63.262  -10.353 23.211  1.00 39.79  ? 35  THR D OG1 1 
ATOM   7097  C  CG2 . THR D 1 35  ? 61.171  -9.196  23.258  1.00 36.39  ? 35  THR D CG2 1 
ATOM   7098  N  N   . VAL D 1 36  ? 61.255  -9.073  19.602  1.00 28.68  ? 36  VAL D N   1 
ATOM   7099  C  CA  . VAL D 1 36  ? 60.302  -8.414  18.737  1.00 29.30  ? 36  VAL D CA  1 
ATOM   7100  C  C   . VAL D 1 36  ? 59.669  -9.439  17.800  1.00 31.98  ? 36  VAL D C   1 
ATOM   7101  O  O   . VAL D 1 36  ? 58.465  -9.441  17.635  1.00 37.34  ? 36  VAL D O   1 
ATOM   7102  C  CB  . VAL D 1 36  ? 60.932  -7.261  17.944  1.00 29.69  ? 36  VAL D CB  1 
ATOM   7103  C  CG1 . VAL D 1 36  ? 60.036  -6.756  16.808  1.00 28.24  ? 36  VAL D CG1 1 
ATOM   7104  C  CG2 . VAL D 1 36  ? 61.357  -6.136  18.865  1.00 30.27  ? 36  VAL D CG2 1 
ATOM   7105  N  N   . ARG D 1 37  ? 60.457  -10.294 17.161  1.00 34.95  ? 37  ARG D N   1 
ATOM   7106  C  CA  . ARG D 1 37  ? 59.891  -11.275 16.256  1.00 36.13  ? 37  ARG D CA  1 
ATOM   7107  C  C   . ARG D 1 37  ? 58.895  -12.185 16.959  1.00 35.74  ? 37  ARG D C   1 
ATOM   7108  O  O   . ARG D 1 37  ? 57.890  -12.547 16.355  1.00 44.34  ? 37  ARG D O   1 
ATOM   7109  C  CB  . ARG D 1 37  ? 61.019  -12.106 15.653  1.00 44.28  ? 37  ARG D CB  1 
ATOM   7110  C  CG  . ARG D 1 37  ? 61.801  -11.287 14.639  1.00 51.40  ? 37  ARG D CG  1 
ATOM   7111  C  CD  . ARG D 1 37  ? 63.343  -11.588 14.528  1.00 54.74  ? 37  ARG D CD  1 
ATOM   7112  N  NE  . ARG D 1 37  ? 63.600  -12.883 13.898  1.00 51.25  ? 37  ARG D NE  1 
ATOM   7113  C  CZ  . ARG D 1 37  ? 62.946  -13.281 12.826  1.00 51.90  ? 37  ARG D CZ  1 
ATOM   7114  N  NH1 . ARG D 1 37  ? 62.473  -12.373 11.989  1.00 59.18  ? 37  ARG D NH1 1 
ATOM   7115  N  NH2 . ARG D 1 37  ? 62.824  -14.570 12.558  1.00 55.20  ? 37  ARG D NH2 1 
ATOM   7116  N  N   . ASP D 1 38  ? 59.170  -12.597 18.206  1.00 40.12  ? 38  ASP D N   1 
ATOM   7117  C  CA  . ASP D 1 38  ? 58.230  -13.454 18.933  1.00 52.72  ? 38  ASP D CA  1 
ATOM   7118  C  C   . ASP D 1 38  ? 56.898  -12.739 19.159  1.00 46.20  ? 38  ASP D C   1 
ATOM   7119  O  O   . ASP D 1 38  ? 55.826  -13.333 19.002  1.00 41.15  ? 38  ASP D O   1 
ATOM   7120  C  CB  . ASP D 1 38  ? 58.643  -13.789 20.364  1.00 64.82  ? 38  ASP D CB  1 
ATOM   7121  C  CG  . ASP D 1 38  ? 59.624  -14.930 20.506  1.00 75.34  ? 38  ASP D CG  1 
ATOM   7122  O  OD1 . ASP D 1 38  ? 59.489  -15.906 19.745  1.00 82.25  ? 38  ASP D OD1 1 
ATOM   7123  O  OD2 . ASP D 1 38  ? 60.513  -14.806 21.365  1.00 84.81  ? 38  ASP D OD2 1 
ATOM   7124  N  N   . LEU D 1 39  ? 56.997  -11.484 19.606  1.00 35.49  ? 39  LEU D N   1 
ATOM   7125  C  CA  . LEU D 1 39  ? 55.824  -10.695 19.868  1.00 34.37  ? 39  LEU D CA  1 
ATOM   7126  C  C   . LEU D 1 39  ? 54.994  -10.516 18.598  1.00 31.40  ? 39  LEU D C   1 
ATOM   7127  O  O   . LEU D 1 39  ? 53.773  -10.606 18.658  1.00 41.66  ? 39  LEU D O   1 
ATOM   7128  C  CB  . LEU D 1 39  ? 56.126  -9.333  20.458  1.00 33.25  ? 39  LEU D CB  1 
ATOM   7129  C  CG  . LEU D 1 39  ? 54.816  -8.541  20.422  1.00 38.18  ? 39  LEU D CG  1 
ATOM   7130  C  CD1 . LEU D 1 39  ? 54.214  -8.526  21.791  1.00 39.72  ? 39  LEU D CD1 1 
ATOM   7131  C  CD2 . LEU D 1 39  ? 54.884  -7.204  19.766  1.00 38.96  ? 39  LEU D CD2 1 
ATOM   7132  N  N   . LEU D 1 40  ? 55.616  -10.270 17.450  1.00 32.81  ? 40  LEU D N   1 
ATOM   7133  C  CA  . LEU D 1 40  ? 54.852  -10.018 16.236  1.00 32.52  ? 40  LEU D CA  1 
ATOM   7134  C  C   . LEU D 1 40  ? 53.988  -11.228 15.895  1.00 33.07  ? 40  LEU D C   1 
ATOM   7135  O  O   . LEU D 1 40  ? 52.919  -11.088 15.318  1.00 34.05  ? 40  LEU D O   1 
ATOM   7136  C  CB  . LEU D 1 40  ? 55.754  -9.672  15.050  1.00 32.75  ? 40  LEU D CB  1 
ATOM   7137  C  CG  . LEU D 1 40  ? 56.493  -8.340  15.148  1.00 36.15  ? 40  LEU D CG  1 
ATOM   7138  C  CD1 . LEU D 1 40  ? 57.362  -8.170  13.935  1.00 40.79  ? 40  LEU D CD1 1 
ATOM   7139  C  CD2 . LEU D 1 40  ? 55.601  -7.134  15.313  1.00 36.68  ? 40  LEU D CD2 1 
ATOM   7140  N  N   . SER D 1 41  ? 54.478  -12.424 16.202  1.00 37.36  ? 41  SER D N   1 
ATOM   7141  C  CA  . SER D 1 41  ? 53.748  -13.631 15.844  1.00 39.95  ? 41  SER D CA  1 
ATOM   7142  C  C   . SER D 1 41  ? 52.603  -13.879 16.829  1.00 35.02  ? 41  SER D C   1 
ATOM   7143  O  O   . SER D 1 41  ? 51.756  -14.710 16.587  1.00 33.93  ? 41  SER D O   1 
ATOM   7144  C  CB  . SER D 1 41  ? 54.690  -14.817 15.768  1.00 42.59  ? 41  SER D CB  1 
ATOM   7145  O  OG  . SER D 1 41  ? 55.199  -15.138 17.065  1.00 43.14  ? 41  SER D OG  1 
ATOM   7146  N  N   . ASP D 1 42  ? 52.566  -13.161 17.948  1.00 33.15  ? 42  ASP D N   1 
ATOM   7147  C  CA  . ASP D 1 42  ? 51.549  -13.381 18.946  1.00 32.44  ? 42  ASP D CA  1 
ATOM   7148  C  C   . ASP D 1 42  ? 50.595  -12.193 19.072  1.00 32.21  ? 42  ASP D C   1 
ATOM   7149  O  O   . ASP D 1 42  ? 49.665  -12.222 19.875  1.00 35.12  ? 42  ASP D O   1 
ATOM   7150  C  CB  . ASP D 1 42  ? 52.201  -13.602 20.292  1.00 35.19  ? 42  ASP D CB  1 
ATOM   7151  C  CG  . ASP D 1 42  ? 52.757  -15.002 20.552  1.00 42.67  ? 42  ASP D CG  1 
ATOM   7152  O  OD1 . ASP D 1 42  ? 52.357  -16.024 19.884  1.00 47.46  ? 42  ASP D OD1 1 
ATOM   7153  O  OD2 . ASP D 1 42  ? 53.599  -15.068 21.443  1.00 47.12  ? 42  ASP D OD2 1 
ATOM   7154  N  N   . VAL D 1 43  ? 50.803  -11.122 18.311  1.00 31.95  ? 43  VAL D N   1 
ATOM   7155  C  CA  . VAL D 1 43  ? 50.082  -9.888  18.604  1.00 30.79  ? 43  VAL D CA  1 
ATOM   7156  C  C   . VAL D 1 43  ? 48.604  -10.081 18.279  1.00 25.43  ? 43  VAL D C   1 
ATOM   7157  O  O   . VAL D 1 43  ? 47.769  -9.606  19.038  1.00 23.75  ? 43  VAL D O   1 
ATOM   7158  C  CB  . VAL D 1 43  ? 50.689  -8.659  17.909  1.00 31.37  ? 43  VAL D CB  1 
ATOM   7159  C  CG1 . VAL D 1 43  ? 50.484  -8.756  16.431  1.00 33.60  ? 43  VAL D CG1 1 
ATOM   7160  C  CG2 . VAL D 1 43  ? 50.113  -7.358  18.412  1.00 29.12  ? 43  VAL D CG2 1 
ATOM   7161  N  N   . ALA D 1 44  ? 48.259  -10.860 17.242  1.00 25.78  ? 44  ALA D N   1 
ATOM   7162  C  CA  . ALA D 1 44  ? 46.841  -11.101 16.956  1.00 27.94  ? 44  ALA D CA  1 
ATOM   7163  C  C   . ALA D 1 44  ? 46.186  -11.852 18.101  1.00 31.30  ? 44  ALA D C   1 
ATOM   7164  O  O   . ALA D 1 44  ? 45.028  -11.575 18.384  1.00 42.01  ? 44  ALA D O   1 
ATOM   7165  C  CB  . ALA D 1 44  ? 46.593  -11.871 15.688  1.00 26.18  ? 44  ALA D CB  1 
ATOM   7166  N  N   . SER D 1 45  ? 46.888  -12.793 18.758  1.00 31.06  ? 45  SER D N   1 
ATOM   7167  C  CA  . SER D 1 45  ? 46.211  -13.572 19.783  1.00 30.83  ? 45  SER D CA  1 
ATOM   7168  C  C   . SER D 1 45  ? 46.108  -12.790 21.083  1.00 27.33  ? 45  SER D C   1 
ATOM   7169  O  O   . SER D 1 45  ? 45.127  -12.988 21.807  1.00 29.22  ? 45  SER D O   1 
ATOM   7170  C  CB  . SER D 1 45  ? 46.762  -14.950 19.978  1.00 32.56  ? 45  SER D CB  1 
ATOM   7171  O  OG  . SER D 1 45  ? 48.145  -14.873 20.157  1.00 41.50  ? 45  SER D OG  1 
ATOM   7172  N  N   . LEU D 1 46  ? 47.028  -11.844 21.313  1.00 23.14  ? 46  LEU D N   1 
ATOM   7173  C  CA  . LEU D 1 46  ? 46.862  -10.907 22.408  1.00 26.94  ? 46  LEU D CA  1 
ATOM   7174  C  C   . LEU D 1 46  ? 45.647  -10.002 22.173  1.00 29.91  ? 46  LEU D C   1 
ATOM   7175  O  O   . LEU D 1 46  ? 44.884  -9.698  23.100  1.00 29.83  ? 46  LEU D O   1 
ATOM   7176  C  CB  . LEU D 1 46  ? 48.149  -10.118 22.631  1.00 27.93  ? 46  LEU D CB  1 
ATOM   7177  C  CG  . LEU D 1 46  ? 49.317  -10.958 23.137  1.00 30.78  ? 46  LEU D CG  1 
ATOM   7178  C  CD1 . LEU D 1 46  ? 50.599  -10.133 23.197  1.00 33.87  ? 46  LEU D CD1 1 
ATOM   7179  C  CD2 . LEU D 1 46  ? 49.001  -11.553 24.498  1.00 29.95  ? 46  LEU D CD2 1 
ATOM   7180  N  N   . GLU D 1 47  ? 45.470  -9.560  20.930  1.00 30.27  ? 47  GLU D N   1 
ATOM   7181  C  CA  . GLU D 1 47  ? 44.319  -8.754  20.580  1.00 32.41  ? 47  GLU D CA  1 
ATOM   7182  C  C   . GLU D 1 47  ? 43.050  -9.534  20.948  1.00 31.49  ? 47  GLU D C   1 
ATOM   7183  O  O   . GLU D 1 47  ? 42.196  -8.988  21.624  1.00 37.90  ? 47  GLU D O   1 
ATOM   7184  C  CB  . GLU D 1 47  ? 44.479  -8.337  19.121  1.00 32.26  ? 47  GLU D CB  1 
ATOM   7185  C  CG  . GLU D 1 47  ? 43.321  -7.478  18.629  1.00 34.29  ? 47  GLU D CG  1 
ATOM   7186  C  CD  . GLU D 1 47  ? 43.325  -7.313  17.129  1.00 38.27  ? 47  GLU D CD  1 
ATOM   7187  O  OE1 . GLU D 1 47  ? 43.473  -6.179  16.649  1.00 40.29  ? 47  GLU D OE1 1 
ATOM   7188  O  OE2 . GLU D 1 47  ? 43.170  -8.319  16.444  1.00 43.91  ? 47  GLU D OE2 1 
ATOM   7189  N  N   . ARG D 1 48  ? 42.949  -10.824 20.599  1.00 29.14  ? 48  ARG D N   1 
ATOM   7190  C  CA  . ARG D 1 48  ? 41.765  -11.591 20.961  1.00 31.91  ? 48  ARG D CA  1 
ATOM   7191  C  C   . ARG D 1 48  ? 41.640  -11.818 22.459  1.00 31.15  ? 48  ARG D C   1 
ATOM   7192  O  O   . ARG D 1 48  ? 40.541  -11.716 22.982  1.00 39.65  ? 48  ARG D O   1 
ATOM   7193  C  CB  . ARG D 1 48  ? 41.703  -12.959 20.308  1.00 34.92  ? 48  ARG D CB  1 
ATOM   7194  C  CG  . ARG D 1 48  ? 41.532  -12.741 18.822  1.00 38.25  ? 48  ARG D CG  1 
ATOM   7195  C  CD  . ARG D 1 48  ? 41.130  -14.049 18.214  1.00 46.44  ? 48  ARG D CD  1 
ATOM   7196  N  NE  . ARG D 1 48  ? 42.194  -15.046 18.365  1.00 58.26  ? 48  ARG D NE  1 
ATOM   7197  C  CZ  . ARG D 1 48  ? 43.313  -15.132 17.641  1.00 57.15  ? 48  ARG D CZ  1 
ATOM   7198  N  NH1 . ARG D 1 48  ? 43.598  -14.274 16.693  1.00 51.79  ? 48  ARG D NH1 1 
ATOM   7199  N  NH2 . ARG D 1 48  ? 44.184  -16.092 17.872  1.00 65.76  ? 48  ARG D NH2 1 
ATOM   7200  N  N   . ALA D 1 49  ? 42.731  -12.138 23.153  1.00 27.98  ? 49  ALA D N   1 
ATOM   7201  C  CA  . ALA D 1 49  ? 42.635  -12.396 24.584  1.00 30.52  ? 49  ALA D CA  1 
ATOM   7202  C  C   . ALA D 1 49  ? 42.012  -11.219 25.343  1.00 33.37  ? 49  ALA D C   1 
ATOM   7203  O  O   . ALA D 1 49  ? 41.092  -11.406 26.170  1.00 37.77  ? 49  ALA D O   1 
ATOM   7204  C  CB  . ALA D 1 49  ? 43.989  -12.668 25.142  1.00 30.45  ? 49  ALA D CB  1 
ATOM   7205  N  N   . VAL D 1 50  ? 42.532  -10.020 25.030  1.00 28.94  ? 50  VAL D N   1 
ATOM   7206  C  CA  . VAL D 1 50  ? 42.120  -8.806  25.706  1.00 29.29  ? 50  VAL D CA  1 
ATOM   7207  C  C   . VAL D 1 50  ? 40.723  -8.398  25.249  1.00 28.14  ? 50  VAL D C   1 
ATOM   7208  O  O   . VAL D 1 50  ? 39.933  -7.893  26.032  1.00 32.74  ? 50  VAL D O   1 
ATOM   7209  C  CB  . VAL D 1 50  ? 43.084  -7.634  25.472  1.00 32.00  ? 50  VAL D CB  1 
ATOM   7210  C  CG1 . VAL D 1 50  ? 42.565  -6.370  26.139  1.00 31.95  ? 50  VAL D CG1 1 
ATOM   7211  C  CG2 . VAL D 1 50  ? 44.490  -7.914  25.954  1.00 30.03  ? 50  VAL D CG2 1 
ATOM   7212  N  N   . GLY D 1 51  ? 40.419  -8.601  23.977  1.00 26.56  ? 51  GLY D N   1 
ATOM   7213  C  CA  . GLY D 1 51  ? 39.207  -8.039  23.428  1.00 32.37  ? 51  GLY D CA  1 
ATOM   7214  C  C   . GLY D 1 51  ? 37.974  -8.943  23.537  1.00 37.02  ? 51  GLY D C   1 
ATOM   7215  O  O   . GLY D 1 51  ? 36.859  -8.427  23.653  1.00 35.31  ? 51  GLY D O   1 
ATOM   7216  N  N   . PHE D 1 52  ? 38.158  -10.269 23.429  1.00 42.06  ? 52  PHE D N   1 
ATOM   7217  C  CA  . PHE D 1 52  ? 37.028  -11.166 23.214  1.00 43.79  ? 52  PHE D CA  1 
ATOM   7218  C  C   . PHE D 1 52  ? 35.989  -11.004 24.329  1.00 40.31  ? 52  PHE D C   1 
ATOM   7219  O  O   . PHE D 1 52  ? 34.798  -10.930 24.052  1.00 41.74  ? 52  PHE D O   1 
ATOM   7220  C  CB  . PHE D 1 52  ? 37.429  -12.644 23.132  1.00 40.89  ? 52  PHE D CB  1 
ATOM   7221  C  CG  . PHE D 1 52  ? 36.182  -13.489 22.964  1.00 37.31  ? 52  PHE D CG  1 
ATOM   7222  C  CD1 . PHE D 1 52  ? 35.602  -13.607 21.726  1.00 37.94  ? 52  PHE D CD1 1 
ATOM   7223  C  CD2 . PHE D 1 52  ? 35.554  -14.108 24.042  1.00 37.80  ? 52  PHE D CD2 1 
ATOM   7224  C  CE1 . PHE D 1 52  ? 34.477  -14.406 21.537  1.00 39.07  ? 52  PHE D CE1 1 
ATOM   7225  C  CE2 . PHE D 1 52  ? 34.392  -14.858 23.868  1.00 34.54  ? 52  PHE D CE2 1 
ATOM   7226  C  CZ  . PHE D 1 52  ? 33.851  -14.997 22.611  1.00 36.26  ? 52  PHE D CZ  1 
ATOM   7227  N  N   . ARG D 1 53  ? 36.451  -10.901 25.580  1.00 39.03  ? 53  ARG D N   1 
ATOM   7228  C  CA  . ARG D 1 53  ? 35.551  -10.877 26.713  1.00 47.67  ? 53  ARG D CA  1 
ATOM   7229  C  C   . ARG D 1 53  ? 34.740  -9.580  26.780  1.00 50.83  ? 53  ARG D C   1 
ATOM   7230  O  O   . ARG D 1 53  ? 33.809  -9.516  27.585  1.00 48.64  ? 53  ARG D O   1 
ATOM   7231  C  CB  . ARG D 1 53  ? 36.388  -11.147 27.970  1.00 61.33  ? 53  ARG D CB  1 
ATOM   7232  C  CG  . ARG D 1 53  ? 37.145  -9.996  28.632  1.00 61.63  ? 53  ARG D CG  1 
ATOM   7233  C  CD  . ARG D 1 53  ? 37.443  -10.297 30.152  1.00 55.70  ? 53  ARG D CD  1 
ATOM   7234  N  NE  . ARG D 1 53  ? 38.753  -9.830  30.580  1.00 41.47  ? 53  ARG D NE  1 
ATOM   7235  C  CZ  . ARG D 1 53  ? 39.806  -10.117 29.818  1.00 47.84  ? 53  ARG D CZ  1 
ATOM   7236  N  NH1 . ARG D 1 53  ? 39.722  -10.867 28.717  1.00 52.46  ? 53  ARG D NH1 1 
ATOM   7237  N  NH2 . ARG D 1 53  ? 40.987  -9.676  30.153  1.00 54.32  ? 53  ARG D NH2 1 
ATOM   7238  N  N   . ALA D 1 54  ? 35.105  -8.547  25.990  1.00 49.99  ? 54  ALA D N   1 
ATOM   7239  C  CA  . ALA D 1 54  ? 34.357  -7.290  25.957  1.00 47.42  ? 54  ALA D CA  1 
ATOM   7240  C  C   . ALA D 1 54  ? 33.550  -7.129  24.660  1.00 44.16  ? 54  ALA D C   1 
ATOM   7241  O  O   . ALA D 1 54  ? 33.141  -6.022  24.330  1.00 38.56  ? 54  ALA D O   1 
ATOM   7242  C  CB  . ALA D 1 54  ? 35.282  -6.117  26.161  1.00 45.31  ? 54  ALA D CB  1 
ATOM   7243  N  N   . GLN D 1 55  ? 33.293  -8.228  23.931  1.00 48.91  ? 55  GLN D N   1 
ATOM   7244  C  CA  . GLN D 1 55  ? 32.555  -8.167  22.671  1.00 53.35  ? 55  GLN D CA  1 
ATOM   7245  C  C   . GLN D 1 55  ? 31.080  -7.920  23.009  1.00 67.66  ? 55  GLN D C   1 
ATOM   7246  O  O   . GLN D 1 55  ? 30.622  -8.120  24.149  1.00 57.95  ? 55  GLN D O   1 
ATOM   7247  C  CB  . GLN D 1 55  ? 32.717  -9.362  21.707  1.00 54.00  ? 55  GLN D CB  1 
ATOM   7248  C  CG  . GLN D 1 55  ? 34.001  -9.364  20.870  1.00 44.96  ? 55  GLN D CG  1 
ATOM   7249  N  N   . PRO D 1 56  ? 30.297  -7.347  22.058  1.00 86.85  ? 56  PRO D N   1 
ATOM   7250  C  CA  . PRO D 1 56  ? 30.827  -6.720  20.837  1.00 79.22  ? 56  PRO D CA  1 
ATOM   7251  C  C   . PRO D 1 56  ? 30.928  -5.189  20.896  1.00 69.50  ? 56  PRO D C   1 
ATOM   7252  O  O   . PRO D 1 56  ? 31.384  -4.587  19.933  1.00 57.90  ? 56  PRO D O   1 
ATOM   7253  C  CB  . PRO D 1 56  ? 29.832  -7.250  19.764  1.00 62.83  ? 56  PRO D CB  1 
ATOM   7254  C  CG  . PRO D 1 56  ? 28.569  -7.575  20.549  1.00 72.16  ? 56  PRO D CG  1 
ATOM   7255  C  CD  . PRO D 1 56  ? 28.824  -7.312  22.050  1.00 78.15  ? 56  PRO D CD  1 
ATOM   7256  N  N   . ASP D 1 57  ? 30.563  -4.576  22.050  1.00 59.17  ? 57  ASP D N   1 
ATOM   7257  C  CA  . ASP D 1 57  ? 30.749  -3.168  22.360  1.00 52.67  ? 57  ASP D CA  1 
ATOM   7258  C  C   . ASP D 1 57  ? 32.248  -2.752  22.230  1.00 55.93  ? 57  ASP D C   1 
ATOM   7259  O  O   . ASP D 1 57  ? 32.579  -1.593  21.917  1.00 59.66  ? 57  ASP D O   1 
ATOM   7260  C  CB  . ASP D 1 57  ? 30.009  -2.888  23.680  1.00 39.37  ? 57  ASP D CB  1 
ATOM   7261  N  N   . GLY D 1 58  ? 33.184  -3.686  22.473  1.00 50.41  ? 58  GLY D N   1 
ATOM   7262  C  CA  . GLY D 1 58  ? 34.588  -3.348  22.671  1.00 42.62  ? 58  GLY D CA  1 
ATOM   7263  C  C   . GLY D 1 58  ? 35.288  -2.809  21.422  1.00 38.98  ? 58  GLY D C   1 
ATOM   7264  O  O   . GLY D 1 58  ? 35.960  -1.781  21.478  1.00 38.08  ? 58  GLY D O   1 
ATOM   7265  N  N   . ARG D 1 59  ? 35.202  -3.544  20.322  1.00 40.58  ? 59  ARG D N   1 
ATOM   7266  C  CA  . ARG D 1 59  ? 35.756  -3.105  19.045  1.00 43.92  ? 59  ARG D CA  1 
ATOM   7267  C  C   . ARG D 1 59  ? 37.261  -2.824  19.141  1.00 40.80  ? 59  ARG D C   1 
ATOM   7268  O  O   . ARG D 1 59  ? 37.766  -1.901  18.496  1.00 37.64  ? 59  ARG D O   1 
ATOM   7269  C  CB  . ARG D 1 59  ? 35.003  -1.861  18.571  1.00 49.95  ? 59  ARG D CB  1 
ATOM   7270  C  CG  . ARG D 1 59  ? 33.594  -2.179  18.104  1.00 63.75  ? 59  ARG D CG  1 
ATOM   7271  C  CD  . ARG D 1 59  ? 32.986  -1.056  17.224  1.00 83.87  ? 59  ARG D CD  1 
ATOM   7272  N  NE  . ARG D 1 59  ? 32.445  0.008   18.085  1.00 99.74  ? 59  ARG D NE  1 
ATOM   7273  C  CZ  . ARG D 1 59  ? 31.379  -0.111  18.893  1.00 87.03  ? 59  ARG D CZ  1 
ATOM   7274  N  NH1 . ARG D 1 59  ? 30.407  -0.951  18.593  1.00 88.91  ? 59  ARG D NH1 1 
ATOM   7275  N  NH2 . ARG D 1 59  ? 31.263  0.637   19.980  1.00 67.66  ? 59  ARG D NH2 1 
ATOM   7276  N  N   . LEU D 1 60  ? 37.974  -3.629  19.933  1.00 35.91  ? 60  LEU D N   1 
ATOM   7277  C  CA  . LEU D 1 60  ? 39.413  -3.477  20.094  1.00 31.89  ? 60  LEU D CA  1 
ATOM   7278  C  C   . LEU D 1 60  ? 40.146  -3.991  18.862  1.00 29.13  ? 60  LEU D C   1 
ATOM   7279  O  O   . LEU D 1 60  ? 39.879  -5.082  18.438  1.00 30.14  ? 60  LEU D O   1 
ATOM   7280  C  CB  . LEU D 1 60  ? 39.871  -4.235  21.329  1.00 29.65  ? 60  LEU D CB  1 
ATOM   7281  C  CG  . LEU D 1 60  ? 41.379  -4.304  21.567  1.00 26.88  ? 60  LEU D CG  1 
ATOM   7282  C  CD1 . LEU D 1 60  ? 41.871  -2.956  21.988  1.00 26.98  ? 60  LEU D CD1 1 
ATOM   7283  C  CD2 . LEU D 1 60  ? 41.635  -5.313  22.652  1.00 26.56  ? 60  LEU D CD2 1 
ATOM   7284  N  N   . SER D 1 61  ? 41.066  -3.203  18.304  1.00 29.62  ? 61  SER D N   1 
ATOM   7285  C  CA  . SER D 1 61  ? 41.903  -3.619  17.192  1.00 30.28  ? 61  SER D CA  1 
ATOM   7286  C  C   . SER D 1 61  ? 43.308  -3.106  17.472  1.00 31.69  ? 61  SER D C   1 
ATOM   7287  O  O   . SER D 1 61  ? 43.469  -2.079  18.113  1.00 30.53  ? 61  SER D O   1 
ATOM   7288  C  CB  . SER D 1 61  ? 41.389  -3.073  15.908  1.00 34.53  ? 61  SER D CB  1 
ATOM   7289  O  OG  . SER D 1 61  ? 41.935  -1.786  15.615  1.00 47.70  ? 61  SER D OG  1 
ATOM   7290  N  N   . CYS D 1 62  ? 44.321  -3.805  16.988  1.00 32.76  ? 62  CYS D N   1 
ATOM   7291  C  CA  . CYS D 1 62  ? 45.676  -3.281  17.041  1.00 28.94  ? 62  CYS D CA  1 
ATOM   7292  C  C   . CYS D 1 62  ? 46.251  -3.374  15.644  1.00 25.90  ? 62  CYS D C   1 
ATOM   7293  O  O   . CYS D 1 62  ? 46.161  -4.416  15.038  1.00 28.35  ? 62  CYS D O   1 
ATOM   7294  C  CB  . CYS D 1 62  ? 46.508  -4.111  17.989  1.00 27.39  ? 62  CYS D CB  1 
ATOM   7295  S  SG  . CYS D 1 62  ? 48.212  -3.527  18.036  1.00 31.12  ? 62  CYS D SG  1 
ATOM   7296  N  N   . VAL D 1 63  ? 46.769  -2.298  15.085  1.00 26.07  ? 63  VAL D N   1 
ATOM   7297  C  CA  . VAL D 1 63  ? 47.482  -2.451  13.823  1.00 26.59  ? 63  VAL D CA  1 
ATOM   7298  C  C   . VAL D 1 63  ? 48.963  -2.194  14.036  1.00 25.66  ? 63  VAL D C   1 
ATOM   7299  O  O   . VAL D 1 63  ? 49.341  -1.202  14.661  1.00 25.42  ? 63  VAL D O   1 
ATOM   7300  C  CB  . VAL D 1 63  ? 46.912  -1.512  12.764  1.00 30.50  ? 63  VAL D CB  1 
ATOM   7301  C  CG1 . VAL D 1 63  ? 47.663  -1.607  11.458  1.00 36.76  ? 63  VAL D CG1 1 
ATOM   7302  C  CG2 . VAL D 1 63  ? 45.453  -1.824  12.519  1.00 31.77  ? 63  VAL D CG2 1 
ATOM   7303  N  N   . THR D 1 64  ? 49.779  -3.139  13.556  1.00 25.19  ? 64  THR D N   1 
ATOM   7304  C  CA  . THR D 1 64  ? 51.203  -3.161  13.832  1.00 25.67  ? 64  THR D CA  1 
ATOM   7305  C  C   . THR D 1 64  ? 51.942  -2.814  12.552  1.00 23.52  ? 64  THR D C   1 
ATOM   7306  O  O   . THR D 1 64  ? 51.713  -3.416  11.507  1.00 20.68  ? 64  THR D O   1 
ATOM   7307  C  CB  . THR D 1 64  ? 51.604  -4.554  14.314  1.00 31.05  ? 64  THR D CB  1 
ATOM   7308  O  OG1 . THR D 1 64  ? 50.789  -4.853  15.444  1.00 30.39  ? 64  THR D OG1 1 
ATOM   7309  C  CG2 . THR D 1 64  ? 53.079  -4.638  14.661  1.00 31.37  ? 64  THR D CG2 1 
ATOM   7310  N  N   . GLY D 1 65  ? 52.842  -1.843  12.659  1.00 23.91  ? 65  GLY D N   1 
ATOM   7311  C  CA  . GLY D 1 65  ? 53.612  -1.398  11.518  1.00 25.62  ? 65  GLY D CA  1 
ATOM   7312  C  C   . GLY D 1 65  ? 55.105  -1.392  11.823  1.00 25.17  ? 65  GLY D C   1 
ATOM   7313  O  O   . GLY D 1 65  ? 55.531  -1.226  12.962  1.00 26.41  ? 65  GLY D O   1 
ATOM   7314  N  N   . ILE D 1 66  ? 55.888  -1.521  10.756  1.00 25.68  ? 66  ILE D N   1 
ATOM   7315  C  CA  . ILE D 1 66  ? 57.326  -1.683  10.820  1.00 22.29  ? 66  ILE D CA  1 
ATOM   7316  C  C   . ILE D 1 66  ? 57.984  -0.666  9.899   1.00 21.83  ? 66  ILE D C   1 
ATOM   7317  O  O   . ILE D 1 66  ? 57.553  -0.506  8.763   1.00 22.33  ? 66  ILE D O   1 
ATOM   7318  C  CB  . ILE D 1 66  ? 57.675  -3.127  10.430  1.00 22.02  ? 66  ILE D CB  1 
ATOM   7319  C  CG1 . ILE D 1 66  ? 56.975  -4.120  11.344  1.00 22.37  ? 66  ILE D CG1 1 
ATOM   7320  C  CG2 . ILE D 1 66  ? 59.192  -3.332  10.444  1.00 23.84  ? 66  ILE D CG2 1 
ATOM   7321  C  CD1 . ILE D 1 66  ? 56.745  -5.442  10.680  1.00 25.52  ? 66  ILE D CD1 1 
ATOM   7322  N  N   . GLY D 1 67  ? 59.024  -0.003  10.385  1.00 20.13  ? 67  GLY D N   1 
ATOM   7323  C  CA  . GLY D 1 67  ? 59.705  1.010   9.605   1.00 25.18  ? 67  GLY D CA  1 
ATOM   7324  C  C   . GLY D 1 67  ? 60.753  0.405   8.669   1.00 28.58  ? 67  GLY D C   1 
ATOM   7325  O  O   . GLY D 1 67  ? 61.048  -0.791  8.713   1.00 31.76  ? 67  GLY D O   1 
ATOM   7326  N  N   . SER D 1 68  ? 61.343  1.290   7.863   1.00 29.28  ? 68  SER D N   1 
ATOM   7327  C  CA  . SER D 1 68  ? 62.277  0.926   6.801   1.00 32.71  ? 68  SER D CA  1 
ATOM   7328  C  C   . SER D 1 68  ? 63.546  0.262   7.334   1.00 33.02  ? 68  SER D C   1 
ATOM   7329  O  O   . SER D 1 68  ? 63.880  -0.848  6.943   1.00 28.80  ? 68  SER D O   1 
ATOM   7330  C  CB  . SER D 1 68  ? 62.637  2.162   6.028   1.00 30.82  ? 68  SER D CB  1 
ATOM   7331  O  OG  . SER D 1 68  ? 63.257  1.816   4.816   1.00 26.97  ? 68  SER D OG  1 
ATOM   7332  N  N   . GLU D 1 69  ? 64.237  0.953   8.250   1.00 31.76  ? 69  GLU D N   1 
ATOM   7333  C  CA  . GLU D 1 69  ? 65.490  0.458   8.806   1.00 32.82  ? 69  GLU D CA  1 
ATOM   7334  C  C   . GLU D 1 69  ? 65.272  -0.765  9.677   1.00 31.23  ? 69  GLU D C   1 
ATOM   7335  O  O   . GLU D 1 69  ? 66.132  -1.638  9.725   1.00 35.65  ? 69  GLU D O   1 
ATOM   7336  C  CB  . GLU D 1 69  ? 66.152  1.566   9.619   1.00 39.28  ? 69  GLU D CB  1 
ATOM   7337  C  CG  . GLU D 1 69  ? 66.130  2.855   8.801   1.00 46.96  ? 69  GLU D CG  1 
ATOM   7338  C  CD  . GLU D 1 69  ? 67.078  3.936   9.182   1.00 48.02  ? 69  GLU D CD  1 
ATOM   7339  O  OE1 . GLU D 1 69  ? 66.960  4.296   10.369  1.00 45.88  ? 69  GLU D OE1 1 
ATOM   7340  O  OE2 . GLU D 1 69  ? 67.841  4.404   8.286   1.00 57.22  ? 69  GLU D OE2 1 
ATOM   7341  N  N   . ALA D 1 70  ? 64.149  -0.797  10.402  1.00 32.30  ? 70  ALA D N   1 
ATOM   7342  C  CA  . ALA D 1 70  ? 63.815  -1.954  11.219  1.00 27.28  ? 70  ALA D CA  1 
ATOM   7343  C  C   . ALA D 1 70  ? 63.506  -3.140  10.321  1.00 23.40  ? 70  ALA D C   1 
ATOM   7344  O  O   . ALA D 1 70  ? 63.794  -4.284  10.663  1.00 27.38  ? 70  ALA D O   1 
ATOM   7345  C  CB  . ALA D 1 70  ? 62.677  -1.646  12.145  1.00 28.41  ? 70  ALA D CB  1 
ATOM   7346  N  N   . TRP D 1 71  ? 62.887  -2.888  9.190   1.00 22.38  ? 71  TRP D N   1 
ATOM   7347  C  CA  . TRP D 1 71  ? 62.514  -3.992  8.320   1.00 28.15  ? 71  TRP D CA  1 
ATOM   7348  C  C   . TRP D 1 71  ? 63.747  -4.829  7.961   1.00 32.19  ? 71  TRP D C   1 
ATOM   7349  O  O   . TRP D 1 71  ? 63.677  -6.068  7.971   1.00 31.70  ? 71  TRP D O   1 
ATOM   7350  C  CB  . TRP D 1 71  ? 61.834  -3.475  7.051   1.00 28.51  ? 71  TRP D CB  1 
ATOM   7351  C  CG  . TRP D 1 71  ? 61.372  -4.631  6.222   1.00 28.23  ? 71  TRP D CG  1 
ATOM   7352  C  CD1 . TRP D 1 71  ? 62.129  -5.395  5.397   1.00 28.91  ? 71  TRP D CD1 1 
ATOM   7353  C  CD2 . TRP D 1 71  ? 60.059  -5.211  6.234   1.00 29.99  ? 71  TRP D CD2 1 
ATOM   7354  N  NE1 . TRP D 1 71  ? 61.358  -6.395  4.875   1.00 30.32  ? 71  TRP D NE1 1 
ATOM   7355  C  CE2 . TRP D 1 71  ? 60.086  -6.309  5.366   1.00 30.00  ? 71  TRP D CE2 1 
ATOM   7356  C  CE3 . TRP D 1 71  ? 58.861  -4.899  6.876   1.00 32.62  ? 71  TRP D CE3 1 
ATOM   7357  C  CZ2 . TRP D 1 71  ? 58.967  -7.097  5.122   1.00 30.47  ? 71  TRP D CZ2 1 
ATOM   7358  C  CZ3 . TRP D 1 71  ? 57.767  -5.699  6.666   1.00 32.92  ? 71  TRP D CZ3 1 
ATOM   7359  C  CH2 . TRP D 1 71  ? 57.829  -6.798  5.812   1.00 33.42  ? 71  TRP D CH2 1 
ATOM   7360  N  N   . ASP D 1 72  ? 64.857  -4.122  7.668   1.00 35.74  ? 72  ASP D N   1 
ATOM   7361  C  CA  . ASP D 1 72  ? 66.134  -4.735  7.287   1.00 37.52  ? 72  ASP D CA  1 
ATOM   7362  C  C   . ASP D 1 72  ? 66.787  -5.482  8.458   1.00 37.05  ? 72  ASP D C   1 
ATOM   7363  O  O   . ASP D 1 72  ? 67.409  -6.503  8.255   1.00 36.46  ? 72  ASP D O   1 
ATOM   7364  C  CB  . ASP D 1 72  ? 67.089  -3.711  6.687   1.00 33.27  ? 72  ASP D CB  1 
ATOM   7365  C  CG  . ASP D 1 72  ? 66.629  -3.150  5.357   1.00 35.50  ? 72  ASP D CG  1 
ATOM   7366  O  OD1 . ASP D 1 72  ? 65.940  -3.921  4.598   1.00 34.60  ? 72  ASP D OD1 1 
ATOM   7367  O  OD2 . ASP D 1 72  ? 66.980  -1.975  5.087   1.00 38.79  ? 72  ASP D OD2 1 
ATOM   7368  N  N   . ARG D 1 73  ? 66.620  -5.010  9.690   1.00 34.07  ? 73  ARG D N   1 
ATOM   7369  C  CA  . ARG D 1 73  ? 67.138  -5.711  10.849  1.00 31.89  ? 73  ARG D CA  1 
ATOM   7370  C  C   . ARG D 1 73  ? 66.349  -6.985  11.134  1.00 36.40  ? 73  ARG D C   1 
ATOM   7371  O  O   . ARG D 1 73  ? 66.907  -7.910  11.722  1.00 42.16  ? 73  ARG D O   1 
ATOM   7372  C  CB  . ARG D 1 73  ? 67.149  -4.835  12.117  1.00 34.66  ? 73  ARG D CB  1 
ATOM   7373  C  CG  . ARG D 1 73  ? 67.946  -3.543  11.952  1.00 33.85  ? 73  ARG D CG  1 
ATOM   7374  C  CD  . ARG D 1 73  ? 67.656  -2.575  13.071  1.00 31.09  ? 73  ARG D CD  1 
ATOM   7375  N  NE  . ARG D 1 73  ? 67.997  -3.186  14.370  1.00 31.54  ? 73  ARG D NE  1 
ATOM   7376  C  CZ  . ARG D 1 73  ? 67.734  -2.530  15.515  1.00 34.07  ? 73  ARG D CZ  1 
ATOM   7377  N  NH1 . ARG D 1 73  ? 67.173  -1.334  15.486  1.00 35.44  ? 73  ARG D NH1 1 
ATOM   7378  N  NH2 . ARG D 1 73  ? 67.998  -3.041  16.703  1.00 36.19  ? 73  ARG D NH2 1 
ATOM   7379  N  N   . LEU D 1 74  ? 65.065  -7.050  10.754  1.00 37.48  ? 74  LEU D N   1 
ATOM   7380  C  CA  . LEU D 1 74  ? 64.196  -8.072  11.306  1.00 33.16  ? 74  LEU D CA  1 
ATOM   7381  C  C   . LEU D 1 74  ? 64.043  -9.204  10.332  1.00 30.35  ? 74  LEU D C   1 
ATOM   7382  O  O   . LEU D 1 74  ? 63.768  -10.308 10.748  1.00 32.38  ? 74  LEU D O   1 
ATOM   7383  C  CB  . LEU D 1 74  ? 62.813  -7.526  11.632  1.00 36.65  ? 74  LEU D CB  1 
ATOM   7384  C  CG  . LEU D 1 74  ? 62.719  -6.619  12.855  1.00 39.69  ? 74  LEU D CG  1 
ATOM   7385  C  CD1 . LEU D 1 74  ? 61.291  -6.079  12.922  1.00 38.46  ? 74  LEU D CD1 1 
ATOM   7386  C  CD2 . LEU D 1 74  ? 63.113  -7.343  14.159  1.00 39.34  ? 74  LEU D CD2 1 
ATOM   7387  N  N   . PHE D 1 75  ? 64.094  -8.883  9.058   1.00 36.43  ? 75  PHE D N   1 
ATOM   7388  C  CA  . PHE D 1 75  ? 63.708  -9.833  8.028   1.00 50.70  ? 75  PHE D CA  1 
ATOM   7389  C  C   . PHE D 1 75  ? 64.758  -9.814  6.941   1.00 53.29  ? 75  PHE D C   1 
ATOM   7390  O  O   . PHE D 1 75  ? 65.435  -8.815  6.695   1.00 52.29  ? 75  PHE D O   1 
ATOM   7391  C  CB  . PHE D 1 75  ? 62.386  -9.508  7.329   1.00 51.72  ? 75  PHE D CB  1 
ATOM   7392  C  CG  . PHE D 1 75  ? 61.281  -9.249  8.331   1.00 53.55  ? 75  PHE D CG  1 
ATOM   7393  C  CD1 . PHE D 1 75  ? 60.873  -10.257 9.191   1.00 51.60  ? 75  PHE D CD1 1 
ATOM   7394  C  CD2 . PHE D 1 75  ? 60.679  -8.003  8.415   1.00 52.90  ? 75  PHE D CD2 1 
ATOM   7395  C  CE1 . PHE D 1 75  ? 59.878  -10.024 10.111  1.00 50.01  ? 75  PHE D CE1 1 
ATOM   7396  C  CE2 . PHE D 1 75  ? 59.687  -7.777  9.342   1.00 52.98  ? 75  PHE D CE2 1 
ATOM   7397  C  CZ  . PHE D 1 75  ? 59.295  -8.781  10.193  1.00 52.75  ? 75  PHE D CZ  1 
ATOM   7398  N  N   . SER D 1 76  ? 64.878  -10.969 6.328   1.00 58.55  ? 76  SER D N   1 
ATOM   7399  C  CA  . SER D 1 76  ? 65.484  -11.004 5.023   1.00 67.28  ? 76  SER D CA  1 
ATOM   7400  C  C   . SER D 1 76  ? 64.409  -11.503 4.064   1.00 59.48  ? 76  SER D C   1 
ATOM   7401  O  O   . SER D 1 76  ? 63.332  -11.963 4.466   1.00 70.24  ? 76  SER D O   1 
ATOM   7402  C  CB  . SER D 1 76  ? 66.762  -11.819 5.039   1.00 64.64  ? 76  SER D CB  1 
ATOM   7403  O  OG  . SER D 1 76  ? 66.653  -12.907 5.952   1.00 60.92  ? 76  SER D OG  1 
ATOM   7404  N  N   . GLY D 1 77  ? 64.715  -11.379 2.794   1.00 48.88  ? 77  GLY D N   1 
ATOM   7405  C  CA  . GLY D 1 77  ? 63.711  -11.598 1.773   1.00 44.54  ? 77  GLY D CA  1 
ATOM   7406  C  C   . GLY D 1 77  ? 63.423  -10.258 1.122   1.00 41.38  ? 77  GLY D C   1 
ATOM   7407  O  O   . GLY D 1 77  ? 64.183  -9.301  1.234   1.00 36.29  ? 77  GLY D O   1 
ATOM   7408  N  N   . ALA D 1 78  ? 62.313  -10.205 0.411   1.00 40.91  ? 78  ALA D N   1 
ATOM   7409  C  CA  . ALA D 1 78  ? 61.857  -8.994  -0.232  1.00 41.56  ? 78  ALA D CA  1 
ATOM   7410  C  C   . ALA D 1 78  ? 61.561  -7.916  0.824   1.00 47.83  ? 78  ALA D C   1 
ATOM   7411  O  O   . ALA D 1 78  ? 61.203  -8.233  1.969   1.00 38.90  ? 78  ALA D O   1 
ATOM   7412  C  CB  . ALA D 1 78  ? 60.629  -9.342  -1.056  1.00 42.08  ? 78  ALA D CB  1 
ATOM   7413  N  N   . ARG D 1 79  ? 61.742  -6.647  0.403   1.00 48.92  ? 79  ARG D N   1 
ATOM   7414  C  CA  . ARG D 1 79  ? 61.129  -5.489  1.020   1.00 42.98  ? 79  ARG D CA  1 
ATOM   7415  C  C   . ARG D 1 79  ? 59.816  -5.099  0.320   1.00 43.04  ? 79  ARG D C   1 
ATOM   7416  O  O   . ARG D 1 79  ? 59.652  -5.248  -0.888  1.00 42.45  ? 79  ARG D O   1 
ATOM   7417  C  CB  . ARG D 1 79  ? 62.103  -4.320  0.947   1.00 34.15  ? 79  ARG D CB  1 
ATOM   7418  C  CG  . ARG D 1 79  ? 63.279  -4.623  1.848   1.00 33.43  ? 79  ARG D CG  1 
ATOM   7419  C  CD  . ARG D 1 79  ? 64.266  -3.520  1.709   1.00 38.68  ? 79  ARG D CD  1 
ATOM   7420  N  NE  . ARG D 1 79  ? 63.605  -2.226  1.838   1.00 35.40  ? 79  ARG D NE  1 
ATOM   7421  C  CZ  . ARG D 1 79  ? 63.644  -1.512  2.922   1.00 35.58  ? 79  ARG D CZ  1 
ATOM   7422  N  NH1 . ARG D 1 79  ? 64.220  -1.926  4.024   1.00 41.18  ? 79  ARG D NH1 1 
ATOM   7423  N  NH2 . ARG D 1 79  ? 63.044  -0.362  2.947   1.00 41.35  ? 79  ARG D NH2 1 
ATOM   7424  N  N   . PRO D 1 80  ? 58.836  -4.539  1.061   1.00 42.80  ? 80  PRO D N   1 
ATOM   7425  C  CA  . PRO D 1 80  ? 57.716  -3.872  0.416   1.00 36.47  ? 80  PRO D CA  1 
ATOM   7426  C  C   . PRO D 1 80  ? 58.297  -2.777  -0.482  1.00 31.57  ? 80  PRO D C   1 
ATOM   7427  O  O   . PRO D 1 80  ? 59.215  -2.045  -0.094  1.00 29.67  ? 80  PRO D O   1 
ATOM   7428  C  CB  . PRO D 1 80  ? 56.930  -3.313  1.606   1.00 38.53  ? 80  PRO D CB  1 
ATOM   7429  C  CG  . PRO D 1 80  ? 57.324  -4.179  2.770   1.00 39.11  ? 80  PRO D CG  1 
ATOM   7430  C  CD  . PRO D 1 80  ? 58.785  -4.465  2.540   1.00 45.25  ? 80  PRO D CD  1 
ATOM   7431  N  N   . ALA D 1 81  ? 57.741  -2.676  -1.687  1.00 32.47  ? 81  ALA D N   1 
ATOM   7432  C  CA  . ALA D 1 81  ? 58.231  -1.764  -2.713  1.00 34.54  ? 81  ALA D CA  1 
ATOM   7433  C  C   . ALA D 1 81  ? 58.282  -0.313  -2.241  1.00 33.95  ? 81  ALA D C   1 
ATOM   7434  O  O   . ALA D 1 81  ? 59.198  0.407   -2.618  1.00 35.61  ? 81  ALA D O   1 
ATOM   7435  C  CB  . ALA D 1 81  ? 57.372  -1.908  -3.947  1.00 35.57  ? 81  ALA D CB  1 
ATOM   7436  N  N   . GLY D 1 82  ? 57.334  0.128   -1.398  1.00 35.44  ? 82  GLY D N   1 
ATOM   7437  C  CA  . GLY D 1 82  ? 57.188  1.543   -1.085  1.00 33.23  ? 82  GLY D CA  1 
ATOM   7438  C  C   . GLY D 1 82  ? 57.894  1.973   0.206   1.00 31.56  ? 82  GLY D C   1 
ATOM   7439  O  O   . GLY D 1 82  ? 57.835  3.142   0.570   1.00 33.84  ? 82  GLY D O   1 
ATOM   7440  N  N   . LEU D 1 83  ? 58.577  1.042   0.875   1.00 29.06  ? 83  LEU D N   1 
ATOM   7441  C  CA  . LEU D 1 83  ? 59.020  1.278   2.235   1.00 28.59  ? 83  LEU D CA  1 
ATOM   7442  C  C   . LEU D 1 83  ? 60.347  2.042   2.245   1.00 26.63  ? 83  LEU D C   1 
ATOM   7443  O  O   . LEU D 1 83  ? 61.326  1.582   1.700   1.00 26.48  ? 83  LEU D O   1 
ATOM   7444  C  CB  . LEU D 1 83  ? 59.117  -0.062  2.965   1.00 27.11  ? 83  LEU D CB  1 
ATOM   7445  C  CG  . LEU D 1 83  ? 59.549  0.015   4.429   1.00 26.92  ? 83  LEU D CG  1 
ATOM   7446  C  CD1 . LEU D 1 83  ? 58.606  0.911   5.219   1.00 28.78  ? 83  LEU D CD1 1 
ATOM   7447  C  CD2 . LEU D 1 83  ? 59.595  -1.397  4.999   1.00 28.37  ? 83  LEU D CD2 1 
ATOM   7448  N  N   . HIS D 1 84  ? 60.345  3.246   2.825   1.00 26.31  ? 84  HIS D N   1 
ATOM   7449  C  CA  . HIS D 1 84  ? 61.510  4.092   2.978   1.00 25.50  ? 84  HIS D CA  1 
ATOM   7450  C  C   . HIS D 1 84  ? 61.309  4.910   4.242   1.00 26.80  ? 84  HIS D C   1 
ATOM   7451  O  O   . HIS D 1 84  ? 60.215  4.942   4.795   1.00 22.39  ? 84  HIS D O   1 
ATOM   7452  C  CB  . HIS D 1 84  ? 61.723  5.026   1.778   1.00 25.00  ? 84  HIS D CB  1 
ATOM   7453  C  CG  . HIS D 1 84  ? 60.487  5.689   1.284   1.00 26.22  ? 84  HIS D CG  1 
ATOM   7454  N  ND1 . HIS D 1 84  ? 59.737  5.202   0.231   1.00 28.45  ? 84  HIS D ND1 1 
ATOM   7455  C  CD2 . HIS D 1 84  ? 59.865  6.792   1.713   1.00 27.75  ? 84  HIS D CD2 1 
ATOM   7456  C  CE1 . HIS D 1 84  ? 58.691  6.000   0.039   1.00 30.47  ? 84  HIS D CE1 1 
ATOM   7457  N  NE2 . HIS D 1 84  ? 58.738  6.960   0.938   1.00 31.74  ? 84  HIS D NE2 1 
ATOM   7458  N  N   . PRO D 1 85  ? 62.367  5.586   4.746   1.00 27.59  ? 85  PRO D N   1 
ATOM   7459  C  CA  . PRO D 1 85  ? 62.207  6.491   5.871   1.00 25.67  ? 85  PRO D CA  1 
ATOM   7460  C  C   . PRO D 1 85  ? 61.336  7.665   5.469   1.00 25.04  ? 85  PRO D C   1 
ATOM   7461  O  O   . PRO D 1 85  ? 61.306  8.028   4.305   1.00 24.99  ? 85  PRO D O   1 
ATOM   7462  C  CB  . PRO D 1 85  ? 63.632  6.916   6.163   1.00 24.65  ? 85  PRO D CB  1 
ATOM   7463  C  CG  . PRO D 1 85  ? 64.438  5.783   5.639   1.00 25.90  ? 85  PRO D CG  1 
ATOM   7464  C  CD  . PRO D 1 85  ? 63.768  5.462   4.324   1.00 25.28  ? 85  PRO D CD  1 
ATOM   7465  N  N   . PHE D 1 86  ? 60.606  8.207   6.439   1.00 23.72  ? 86  PHE D N   1 
ATOM   7466  C  CA  . PHE D 1 86  ? 59.796  9.384   6.214   1.00 24.74  ? 86  PHE D CA  1 
ATOM   7467  C  C   . PHE D 1 86  ? 60.770  10.438  5.713   1.00 27.08  ? 86  PHE D C   1 
ATOM   7468  O  O   . PHE D 1 86  ? 61.848  10.528  6.255   1.00 23.32  ? 86  PHE D O   1 
ATOM   7469  C  CB  . PHE D 1 86  ? 59.134  9.762   7.543   1.00 25.68  ? 86  PHE D CB  1 
ATOM   7470  C  CG  . PHE D 1 86  ? 58.291  11.022  7.517   1.00 25.17  ? 86  PHE D CG  1 
ATOM   7471  C  CD1 . PHE D 1 86  ? 58.867  12.263  7.633   1.00 25.86  ? 86  PHE D CD1 1 
ATOM   7472  C  CD2 . PHE D 1 86  ? 56.919  10.940  7.339   1.00 29.55  ? 86  PHE D CD2 1 
ATOM   7473  C  CE1 . PHE D 1 86  ? 58.080  13.415  7.545   1.00 32.46  ? 86  PHE D CE1 1 
ATOM   7474  C  CE2 . PHE D 1 86  ? 56.124  12.089  7.273   1.00 30.44  ? 86  PHE D CE2 1 
ATOM   7475  C  CZ  . PHE D 1 86  ? 56.701  13.330  7.404   1.00 30.77  ? 86  PHE D CZ  1 
ATOM   7476  N  N   . ARG D 1 87  ? 60.377  11.218  4.696   1.00 31.53  ? 87  ARG D N   1 
ATOM   7477  C  CA  . ARG D 1 87  ? 61.208  12.248  4.106   1.00 31.81  ? 87  ARG D CA  1 
ATOM   7478  C  C   . ARG D 1 87  ? 60.846  13.567  4.775   1.00 30.32  ? 87  ARG D C   1 
ATOM   7479  O  O   . ARG D 1 87  ? 59.700  14.009  4.673   1.00 29.68  ? 87  ARG D O   1 
ATOM   7480  C  CB  . ARG D 1 87  ? 60.910  12.461  2.615   1.00 44.24  ? 87  ARG D CB  1 
ATOM   7481  C  CG  . ARG D 1 87  ? 60.509  11.250  1.787   1.00 58.66  ? 87  ARG D CG  1 
ATOM   7482  C  CD  . ARG D 1 87  ? 60.323  11.561  0.303   1.00 68.97  ? 87  ARG D CD  1 
ATOM   7483  N  NE  . ARG D 1 87  ? 61.217  10.515  -0.210  1.00 78.31  ? 87  ARG D NE  1 
ATOM   7484  C  CZ  . ARG D 1 87  ? 60.904  9.322   -0.703  1.00 75.68  ? 87  ARG D CZ  1 
ATOM   7485  N  NH1 . ARG D 1 87  ? 59.729  9.151   -1.278  1.00 74.86  ? 87  ARG D NH1 1 
ATOM   7486  N  NH2 . ARG D 1 87  ? 61.822  8.356   -0.714  1.00 78.17  ? 87  ARG D NH2 1 
ATOM   7487  N  N   . GLU D 1 88  ? 61.834  14.186  5.438   1.00 28.95  ? 88  GLU D N   1 
ATOM   7488  C  CA  . GLU D 1 88  ? 61.697  15.526  5.975   1.00 28.22  ? 88  GLU D CA  1 
ATOM   7489  C  C   . GLU D 1 88  ? 61.295  16.445  4.833   1.00 28.88  ? 88  GLU D C   1 
ATOM   7490  O  O   . GLU D 1 88  ? 61.649  16.167  3.704   1.00 31.45  ? 88  GLU D O   1 
ATOM   7491  C  CB  . GLU D 1 88  ? 63.049  15.913  6.524   1.00 33.18  ? 88  GLU D CB  1 
ATOM   7492  C  CG  . GLU D 1 88  ? 63.077  16.186  8.027   1.00 48.10  ? 88  GLU D CG  1 
ATOM   7493  C  CD  . GLU D 1 88  ? 64.127  17.269  8.236   1.00 60.21  ? 88  GLU D CD  1 
ATOM   7494  O  OE1 . GLU D 1 88  ? 63.803  18.471  8.472   1.00 63.19  ? 88  GLU D OE1 1 
ATOM   7495  O  OE2 . GLU D 1 88  ? 65.304  16.905  8.032   1.00 72.76  ? 88  GLU D OE2 1 
ATOM   7496  N  N   . LEU D 1 89  ? 60.512  17.486  5.112   1.00 26.93  ? 89  LEU D N   1 
ATOM   7497  C  CA  . LEU D 1 89  ? 60.090  18.445  4.106   1.00 25.76  ? 89  LEU D CA  1 
ATOM   7498  C  C   . LEU D 1 89  ? 60.389  19.818  4.672   1.00 27.83  ? 89  LEU D C   1 
ATOM   7499  O  O   . LEU D 1 89  ? 59.833  20.212  5.714   1.00 24.11  ? 89  LEU D O   1 
ATOM   7500  C  CB  . LEU D 1 89  ? 58.616  18.373  3.719   1.00 29.23  ? 89  LEU D CB  1 
ATOM   7501  C  CG  . LEU D 1 89  ? 58.116  17.081  3.065   1.00 34.30  ? 89  LEU D CG  1 
ATOM   7502  C  CD1 . LEU D 1 89  ? 56.644  17.307  2.660   1.00 38.41  ? 89  LEU D CD1 1 
ATOM   7503  C  CD2 . LEU D 1 89  ? 58.868  16.621  1.860   1.00 31.58  ? 89  LEU D CD2 1 
ATOM   7504  N  N   . ASP D 1 90  ? 61.290  20.513  3.967   1.00 30.74  ? 90  ASP D N   1 
ATOM   7505  C  CA  . ASP D 1 90  ? 61.859  21.744  4.496   1.00 34.95  ? 90  ASP D CA  1 
ATOM   7506  C  C   . ASP D 1 90  ? 61.237  22.883  3.707   1.00 31.51  ? 90  ASP D C   1 
ATOM   7507  O  O   . ASP D 1 90  ? 61.734  23.223  2.650   1.00 35.07  ? 90  ASP D O   1 
ATOM   7508  C  CB  . ASP D 1 90  ? 63.379  21.734  4.450   1.00 38.70  ? 90  ASP D CB  1 
ATOM   7509  C  CG  . ASP D 1 90  ? 63.979  22.331  5.700   1.00 50.22  ? 90  ASP D CG  1 
ATOM   7510  O  OD1 . ASP D 1 90  ? 64.052  21.530  6.645   1.00 63.87  ? 90  ASP D OD1 1 
ATOM   7511  O  OD2 . ASP D 1 90  ? 64.278  23.563  5.751   1.00 51.43  ? 90  ASP D OD2 1 
ATOM   7512  N  N   . GLY D 1 91  ? 60.111  23.395  4.164   1.00 29.49  ? 91  GLY D N   1 
ATOM   7513  C  CA  . GLY D 1 91  ? 59.355  24.325  3.343   1.00 29.57  ? 91  GLY D CA  1 
ATOM   7514  C  C   . GLY D 1 91  ? 59.828  25.752  3.594   1.00 25.40  ? 91  GLY D C   1 
ATOM   7515  O  O   . GLY D 1 91  ? 60.546  26.012  4.542   1.00 24.34  ? 91  GLY D O   1 
ATOM   7516  N  N   . PRO D 1 92  ? 59.422  26.700  2.732   1.00 23.80  ? 92  PRO D N   1 
ATOM   7517  C  CA  . PRO D 1 92  ? 59.747  28.100  2.930   1.00 24.12  ? 92  PRO D CA  1 
ATOM   7518  C  C   . PRO D 1 92  ? 59.371  28.587  4.314   1.00 25.93  ? 92  PRO D C   1 
ATOM   7519  O  O   . PRO D 1 92  ? 60.141  29.328  4.913   1.00 30.20  ? 92  PRO D O   1 
ATOM   7520  C  CB  . PRO D 1 92  ? 58.991  28.868  1.853   1.00 26.68  ? 92  PRO D CB  1 
ATOM   7521  C  CG  . PRO D 1 92  ? 58.266  27.811  1.026   1.00 28.33  ? 92  PRO D CG  1 
ATOM   7522  C  CD  . PRO D 1 92  ? 58.641  26.441  1.516   1.00 25.69  ? 92  PRO D CD  1 
ATOM   7523  N  N   . VAL D 1 93  ? 58.212  28.161  4.837   1.00 28.45  ? 93  VAL D N   1 
ATOM   7524  C  CA  . VAL D 1 93  ? 57.742  28.607  6.144   1.00 24.45  ? 93  VAL D CA  1 
ATOM   7525  C  C   . VAL D 1 93  ? 57.654  27.426  7.099   1.00 23.29  ? 93  VAL D C   1 
ATOM   7526  O  O   . VAL D 1 93  ? 58.066  27.538  8.239   1.00 26.10  ? 93  VAL D O   1 
ATOM   7527  C  CB  . VAL D 1 93  ? 56.382  29.320  6.044   1.00 25.85  ? 93  VAL D CB  1 
ATOM   7528  C  CG1 . VAL D 1 93  ? 55.786  29.574  7.429   1.00 25.68  ? 93  VAL D CG1 1 
ATOM   7529  C  CG2 . VAL D 1 93  ? 56.494  30.595  5.200   1.00 23.90  ? 93  VAL D CG2 1 
ATOM   7530  N  N   . HIS D 1 94  ? 57.086  26.318  6.653   1.00 21.11  ? 94  HIS D N   1 
ATOM   7531  C  CA  . HIS D 1 94  ? 56.751  25.220  7.548   1.00 22.18  ? 94  HIS D CA  1 
ATOM   7532  C  C   . HIS D 1 94  ? 57.555  23.985  7.177   1.00 23.80  ? 94  HIS D C   1 
ATOM   7533  O  O   . HIS D 1 94  ? 57.838  23.733  6.011   1.00 25.37  ? 94  HIS D O   1 
ATOM   7534  C  CB  . HIS D 1 94  ? 55.257  24.868  7.485   1.00 21.21  ? 94  HIS D CB  1 
ATOM   7535  C  CG  . HIS D 1 94  ? 54.337  25.975  7.871   1.00 22.15  ? 94  HIS D CG  1 
ATOM   7536  N  ND1 . HIS D 1 94  ? 54.299  26.469  9.147   1.00 21.86  ? 94  HIS D ND1 1 
ATOM   7537  C  CD2 . HIS D 1 94  ? 53.480  26.716  7.167   1.00 21.62  ? 94  HIS D CD2 1 
ATOM   7538  C  CE1 . HIS D 1 94  ? 53.396  27.434  9.193   1.00 23.64  ? 94  HIS D CE1 1 
ATOM   7539  N  NE2 . HIS D 1 94  ? 52.896  27.605  8.009   1.00 20.43  ? 94  HIS D NE2 1 
ATOM   7540  N  N   . ARG D 1 95  ? 57.874  23.193  8.198   1.00 27.96  ? 95  ARG D N   1 
ATOM   7541  C  CA  . ARG D 1 95  ? 58.772  22.049  8.108   1.00 35.18  ? 95  ARG D CA  1 
ATOM   7542  C  C   . ARG D 1 95  ? 58.123  20.781  8.655   1.00 29.53  ? 95  ARG D C   1 
ATOM   7543  O  O   . ARG D 1 95  ? 57.557  20.793  9.745   1.00 26.67  ? 95  ARG D O   1 
ATOM   7544  C  CB  . ARG D 1 95  ? 59.866  22.553  9.051   1.00 52.15  ? 95  ARG D CB  1 
ATOM   7545  C  CG  . ARG D 1 95  ? 61.184  21.816  9.087   1.00 70.75  ? 95  ARG D CG  1 
ATOM   7546  C  CD  . ARG D 1 95  ? 62.306  22.853  9.402   1.00 81.47  ? 95  ARG D CD  1 
ATOM   7547  N  NE  . ARG D 1 95  ? 63.387  21.919  9.697   1.00 89.42  ? 95  ARG D NE  1 
ATOM   7548  C  CZ  . ARG D 1 95  ? 63.294  20.999  10.654  1.00 92.66  ? 95  ARG D CZ  1 
ATOM   7549  N  NH1 . ARG D 1 95  ? 62.603  21.248  11.760  1.00 88.85  ? 95  ARG D NH1 1 
ATOM   7550  N  NH2 . ARG D 1 95  ? 63.991  19.879  10.549  1.00 102.25 ? 95  ARG D NH2 1 
ATOM   7551  N  N   . ALA D 1 96  ? 58.162  19.696  7.885   1.00 28.49  ? 96  ALA D N   1 
ATOM   7552  C  CA  . ALA D 1 96  ? 57.681  18.409  8.359   1.00 26.56  ? 96  ALA D CA  1 
ATOM   7553  C  C   . ALA D 1 96  ? 58.885  17.603  8.829   1.00 25.29  ? 96  ALA D C   1 
ATOM   7554  O  O   . ALA D 1 96  ? 59.728  17.189  8.054   1.00 25.22  ? 96  ALA D O   1 
ATOM   7555  C  CB  . ALA D 1 96  ? 56.908  17.698  7.286   1.00 28.29  ? 96  ALA D CB  1 
ATOM   7556  N  N   . VAL D 1 97  ? 59.013  17.419  10.132  1.00 26.31  ? 97  VAL D N   1 
ATOM   7557  C  CA  . VAL D 1 97  ? 60.178  16.740  10.672  1.00 26.07  ? 97  VAL D CA  1 
ATOM   7558  C  C   . VAL D 1 97  ? 59.961  15.247  10.560  1.00 25.82  ? 97  VAL D C   1 
ATOM   7559  O  O   . VAL D 1 97  ? 58.801  14.811  10.447  1.00 32.06  ? 97  VAL D O   1 
ATOM   7560  C  CB  . VAL D 1 97  ? 60.466  17.102  12.123  1.00 24.58  ? 97  VAL D CB  1 
ATOM   7561  C  CG1 . VAL D 1 97  ? 60.607  18.599  12.263  1.00 26.84  ? 97  VAL D CG1 1 
ATOM   7562  C  CG2 . VAL D 1 97  ? 59.356  16.644  13.049  1.00 26.60  ? 97  VAL D CG2 1 
ATOM   7563  N  N   . ALA D 1 98  ? 61.106  14.554  10.597  1.00 24.87  ? 98  ALA D N   1 
ATOM   7564  C  CA  . ALA D 1 98  ? 61.182  13.100  10.603  1.00 25.18  ? 98  ALA D CA  1 
ATOM   7565  C  C   . ALA D 1 98  ? 61.777  12.662  11.934  1.00 24.51  ? 98  ALA D C   1 
ATOM   7566  O  O   . ALA D 1 98  ? 62.833  13.129  12.307  1.00 25.84  ? 98  ALA D O   1 
ATOM   7567  C  CB  . ALA D 1 98  ? 62.045  12.632  9.468   1.00 23.38  ? 98  ALA D CB  1 
ATOM   7568  N  N   . THR D 1 99  ? 61.099  11.790  12.673  1.00 23.99  ? 99  THR D N   1 
ATOM   7569  C  CA  . THR D 1 99  ? 61.570  11.387  13.976  1.00 21.87  ? 99  THR D CA  1 
ATOM   7570  C  C   . THR D 1 99  ? 61.641  9.874   14.004  1.00 21.67  ? 99  THR D C   1 
ATOM   7571  O  O   . THR D 1 99  ? 61.078  9.213   13.168  1.00 23.62  ? 99  THR D O   1 
ATOM   7572  C  CB  . THR D 1 99  ? 60.668  11.951  15.055  1.00 24.34  ? 99  THR D CB  1 
ATOM   7573  O  OG1 . THR D 1 99  ? 59.359  11.456  14.825  1.00 24.03  ? 99  THR D OG1 1 
ATOM   7574  C  CG2 . THR D 1 99  ? 60.648  13.466  15.013  1.00 24.67  ? 99  THR D CG2 1 
ATOM   7575  N  N   . PRO D 1 100 ? 62.477  9.292   14.862  1.00 23.91  ? 100 PRO D N   1 
ATOM   7576  C  CA  . PRO D 1 100 ? 62.749  7.852   14.807  1.00 23.95  ? 100 PRO D CA  1 
ATOM   7577  C  C   . PRO D 1 100 ? 61.550  7.019   15.231  1.00 24.14  ? 100 PRO D C   1 
ATOM   7578  O  O   . PRO D 1 100 ? 60.841  7.383   16.190  1.00 28.30  ? 100 PRO D O   1 
ATOM   7579  C  CB  . PRO D 1 100 ? 63.885  7.645   15.798  1.00 24.89  ? 100 PRO D CB  1 
ATOM   7580  C  CG  . PRO D 1 100 ? 63.914  8.910   16.647  1.00 25.67  ? 100 PRO D CG  1 
ATOM   7581  C  CD  . PRO D 1 100 ? 63.240  10.022  15.879  1.00 24.58  ? 100 PRO D CD  1 
ATOM   7582  N  N   . GLY D 1 101 ? 61.413  5.860   14.589  1.00 22.44  ? 101 GLY D N   1 
ATOM   7583  C  CA  . GLY D 1 101 ? 60.390  4.913   14.976  1.00 22.22  ? 101 GLY D CA  1 
ATOM   7584  C  C   . GLY D 1 101 ? 60.545  3.630   14.180  1.00 21.83  ? 101 GLY D C   1 
ATOM   7585  O  O   . GLY D 1 101 ? 60.502  3.642   12.967  1.00 24.62  ? 101 GLY D O   1 
ATOM   7586  N  N   . ASP D 1 102 ? 60.672  2.513   14.873  1.00 21.76  ? 102 ASP D N   1 
ATOM   7587  C  CA  . ASP D 1 102 ? 60.838  1.230   14.224  1.00 22.97  ? 102 ASP D CA  1 
ATOM   7588  C  C   . ASP D 1 102 ? 59.518  0.491   14.165  1.00 21.25  ? 102 ASP D C   1 
ATOM   7589  O  O   . ASP D 1 102 ? 59.286  -0.221  13.215  1.00 24.47  ? 102 ASP D O   1 
ATOM   7590  C  CB  . ASP D 1 102 ? 61.906  0.389   14.929  1.00 25.95  ? 102 ASP D CB  1 
ATOM   7591  C  CG  . ASP D 1 102 ? 63.299  1.004   14.882  1.00 30.01  ? 102 ASP D CG  1 
ATOM   7592  O  OD1 . ASP D 1 102 ? 63.659  1.626   13.855  1.00 32.06  ? 102 ASP D OD1 1 
ATOM   7593  O  OD2 . ASP D 1 102 ? 64.017  0.857   15.844  1.00 29.61  ? 102 ASP D OD2 1 
ATOM   7594  N  N   . LEU D 1 103 ? 58.740  0.550   15.232  1.00 24.51  ? 103 LEU D N   1 
ATOM   7595  C  CA  . LEU D 1 103 ? 57.484  -0.164  15.330  1.00 23.18  ? 103 LEU D CA  1 
ATOM   7596  C  C   . LEU D 1 103 ? 56.407  0.822   15.723  1.00 22.63  ? 103 LEU D C   1 
ATOM   7597  O  O   . LEU D 1 103 ? 56.648  1.737   16.529  1.00 23.96  ? 103 LEU D O   1 
ATOM   7598  C  CB  . LEU D 1 103 ? 57.506  -1.248  16.394  1.00 24.79  ? 103 LEU D CB  1 
ATOM   7599  C  CG  . LEU D 1 103 ? 58.445  -2.420  16.150  1.00 26.43  ? 103 LEU D CG  1 
ATOM   7600  C  CD1 . LEU D 1 103 ? 58.298  -3.372  17.337  1.00 26.17  ? 103 LEU D CD1 1 
ATOM   7601  C  CD2 . LEU D 1 103 ? 58.106  -3.121  14.887  1.00 28.41  ? 103 LEU D CD2 1 
ATOM   7602  N  N   . LEU D 1 104 ? 55.224  0.579   15.143  1.00 23.80  ? 104 LEU D N   1 
ATOM   7603  C  CA  . LEU D 1 104 ? 54.013  1.331   15.441  1.00 24.68  ? 104 LEU D CA  1 
ATOM   7604  C  C   . LEU D 1 104 ? 52.964  0.352   15.938  1.00 22.95  ? 104 LEU D C   1 
ATOM   7605  O  O   . LEU D 1 104 ? 52.745  -0.673  15.307  1.00 25.35  ? 104 LEU D O   1 
ATOM   7606  C  CB  . LEU D 1 104 ? 53.499  2.067   14.206  1.00 25.35  ? 104 LEU D CB  1 
ATOM   7607  C  CG  . LEU D 1 104 ? 52.070  2.625   14.312  1.00 26.23  ? 104 LEU D CG  1 
ATOM   7608  C  CD1 . LEU D 1 104 ? 52.104  3.889   15.172  1.00 27.39  ? 104 LEU D CD1 1 
ATOM   7609  C  CD2 . LEU D 1 104 ? 51.455  2.884   12.955  1.00 26.03  ? 104 LEU D CD2 1 
ATOM   7610  N  N   . PHE D 1 105 ? 52.324  0.675   17.067  1.00 24.90  ? 105 PHE D N   1 
ATOM   7611  C  CA  . PHE D 1 105 ? 51.087  0.003   17.448  1.00 27.08  ? 105 PHE D CA  1 
ATOM   7612  C  C   . PHE D 1 105 ? 49.972  1.053   17.448  1.00 23.20  ? 105 PHE D C   1 
ATOM   7613  O  O   . PHE D 1 105 ? 50.035  2.028   18.204  1.00 21.03  ? 105 PHE D O   1 
ATOM   7614  C  CB  . PHE D 1 105 ? 51.236  -0.701  18.805  1.00 27.32  ? 105 PHE D CB  1 
ATOM   7615  C  CG  . PHE D 1 105 ? 52.354  -1.725  18.810  1.00 26.97  ? 105 PHE D CG  1 
ATOM   7616  C  CD1 . PHE D 1 105 ? 52.170  -2.987  18.258  1.00 26.04  ? 105 PHE D CD1 1 
ATOM   7617  C  CD2 . PHE D 1 105 ? 53.610  -1.391  19.301  1.00 30.48  ? 105 PHE D CD2 1 
ATOM   7618  C  CE1 . PHE D 1 105 ? 53.205  -3.917  18.240  1.00 26.22  ? 105 PHE D CE1 1 
ATOM   7619  C  CE2 . PHE D 1 105 ? 54.653  -2.310  19.238  1.00 29.52  ? 105 PHE D CE2 1 
ATOM   7620  C  CZ  . PHE D 1 105 ? 54.427  -3.585  18.728  1.00 27.09  ? 105 PHE D CZ  1 
ATOM   7621  N  N   . HIS D 1 106 ? 49.022  0.868   16.533  1.00 19.90  ? 106 HIS D N   1 
ATOM   7622  C  CA  . HIS D 1 106 ? 47.841  1.700   16.450  1.00 21.05  ? 106 HIS D CA  1 
ATOM   7623  C  C   . HIS D 1 106 ? 46.684  0.904   17.036  1.00 20.94  ? 106 HIS D C   1 
ATOM   7624  O  O   . HIS D 1 106 ? 46.118  0.031   16.368  1.00 18.89  ? 106 HIS D O   1 
ATOM   7625  C  CB  . HIS D 1 106 ? 47.603  2.120   15.003  1.00 20.91  ? 106 HIS D CB  1 
ATOM   7626  C  CG  . HIS D 1 106 ? 46.409  2.999   14.810  1.00 22.36  ? 106 HIS D CG  1 
ATOM   7627  N  ND1 . HIS D 1 106 ? 45.731  3.077   13.610  1.00 24.64  ? 106 HIS D ND1 1 
ATOM   7628  C  CD2 . HIS D 1 106 ? 45.788  3.823   15.620  1.00 23.37  ? 106 HIS D CD2 1 
ATOM   7629  C  CE1 . HIS D 1 106 ? 44.751  3.956   13.702  1.00 23.25  ? 106 HIS D CE1 1 
ATOM   7630  N  NE2 . HIS D 1 106 ? 44.760  4.445   14.899  1.00 23.80  ? 106 HIS D NE2 1 
ATOM   7631  N  N   . ILE D 1 107 ? 46.377  1.232   18.295  1.00 20.93  ? 107 ILE D N   1 
ATOM   7632  C  CA  . ILE D 1 107 ? 45.428  0.468   19.077  1.00 22.54  ? 107 ILE D CA  1 
ATOM   7633  C  C   . ILE D 1 107 ? 44.162  1.296   19.207  1.00 21.65  ? 107 ILE D C   1 
ATOM   7634  O  O   . ILE D 1 107 ? 44.260  2.454   19.617  1.00 19.72  ? 107 ILE D O   1 
ATOM   7635  C  CB  . ILE D 1 107 ? 46.015  0.138   20.463  1.00 23.54  ? 107 ILE D CB  1 
ATOM   7636  C  CG1 . ILE D 1 107 ? 47.281  -0.629  20.354  1.00 21.62  ? 107 ILE D CG1 1 
ATOM   7637  C  CG2 . ILE D 1 107 ? 45.006  -0.646  21.306  1.00 24.51  ? 107 ILE D CG2 1 
ATOM   7638  C  CD1 . ILE D 1 107 ? 48.042  -0.690  21.659  1.00 24.01  ? 107 ILE D CD1 1 
ATOM   7639  N  N   . ARG D 1 108 ? 43.014  0.693   18.858  1.00 20.72  ? 108 ARG D N   1 
ATOM   7640  C  CA  . ARG D 1 108 ? 41.759  1.411   18.843  1.00 22.58  ? 108 ARG D CA  1 
ATOM   7641  C  C   . ARG D 1 108 ? 40.691  0.565   19.504  1.00 22.89  ? 108 ARG D C   1 
ATOM   7642  O  O   . ARG D 1 108 ? 40.648  -0.628  19.301  1.00 19.46  ? 108 ARG D O   1 
ATOM   7643  C  CB  . ARG D 1 108 ? 41.324  1.690   17.404  1.00 24.56  ? 108 ARG D CB  1 
ATOM   7644  C  CG  . ARG D 1 108 ? 42.087  2.851   16.767  1.00 24.42  ? 108 ARG D CG  1 
ATOM   7645  C  CD  . ARG D 1 108 ? 41.739  2.966   15.304  1.00 26.77  ? 108 ARG D CD  1 
ATOM   7646  N  NE  . ARG D 1 108 ? 42.175  1.808   14.513  1.00 26.30  ? 108 ARG D NE  1 
ATOM   7647  C  CZ  . ARG D 1 108 ? 42.125  1.814   13.191  1.00 27.89  ? 108 ARG D CZ  1 
ATOM   7648  N  NH1 . ARG D 1 108 ? 41.638  2.848   12.554  1.00 25.91  ? 108 ARG D NH1 1 
ATOM   7649  N  NH2 . ARG D 1 108 ? 42.568  0.822   12.463  1.00 28.45  ? 108 ARG D NH2 1 
ATOM   7650  N  N   . ALA D 1 109 ? 39.797  1.212   20.244  1.00 28.54  ? 109 ALA D N   1 
ATOM   7651  C  CA  . ALA D 1 109 ? 38.610  0.553   20.777  1.00 29.39  ? 109 ALA D CA  1 
ATOM   7652  C  C   . ALA D 1 109 ? 37.564  1.591   21.125  1.00 31.41  ? 109 ALA D C   1 
ATOM   7653  O  O   . ALA D 1 109 ? 37.812  2.805   21.044  1.00 28.35  ? 109 ALA D O   1 
ATOM   7654  C  CB  . ALA D 1 109 ? 38.989  -0.218  22.002  1.00 33.95  ? 109 ALA D CB  1 
ATOM   7655  N  N   . SER D 1 110 ? 36.409  1.103   21.585  1.00 34.82  ? 110 SER D N   1 
ATOM   7656  C  CA  . SER D 1 110 ? 35.364  2.007   22.046  1.00 34.60  ? 110 SER D CA  1 
ATOM   7657  C  C   . SER D 1 110 ? 35.659  2.561   23.445  1.00 33.78  ? 110 SER D C   1 
ATOM   7658  O  O   . SER D 1 110 ? 35.046  3.538   23.836  1.00 31.24  ? 110 SER D O   1 
ATOM   7659  C  CB  . SER D 1 110 ? 34.059  1.336   21.983  1.00 34.02  ? 110 SER D CB  1 
ATOM   7660  O  OG  . SER D 1 110 ? 34.032  0.314   22.966  1.00 40.81  ? 110 SER D OG  1 
ATOM   7661  N  N   . ARG D 1 111 ? 36.621  1.988   24.193  1.00 38.63  ? 111 ARG D N   1 
ATOM   7662  C  CA  . ARG D 1 111 ? 36.932  2.438   25.547  1.00 35.89  ? 111 ARG D CA  1 
ATOM   7663  C  C   . ARG D 1 111 ? 38.452  2.453   25.724  1.00 29.48  ? 111 ARG D C   1 
ATOM   7664  O  O   . ARG D 1 111 ? 39.116  1.518   25.263  1.00 26.35  ? 111 ARG D O   1 
ATOM   7665  C  CB  . ARG D 1 111 ? 36.396  1.479   26.625  1.00 42.82  ? 111 ARG D CB  1 
ATOM   7666  C  CG  . ARG D 1 111 ? 35.043  0.800   26.468  1.00 45.81  ? 111 ARG D CG  1 
ATOM   7667  C  CD  . ARG D 1 111 ? 34.814  -0.444  27.388  1.00 48.48  ? 111 ARG D CD  1 
ATOM   7668  N  NE  . ARG D 1 111 ? 35.112  -0.261  28.819  1.00 65.80  ? 111 ARG D NE  1 
ATOM   7669  C  CZ  . ARG D 1 111 ? 34.613  0.595   29.782  1.00 57.35  ? 111 ARG D CZ  1 
ATOM   7670  N  NH1 . ARG D 1 111 ? 33.690  1.490   29.563  1.00 54.41  ? 111 ARG D NH1 1 
ATOM   7671  N  NH2 . ARG D 1 111 ? 35.100  0.609   31.008  1.00 54.89  ? 111 ARG D NH2 1 
ATOM   7672  N  N   . LEU D 1 112 ? 38.975  3.443   26.470  1.00 25.78  ? 112 LEU D N   1 
ATOM   7673  C  CA  . LEU D 1 112 ? 40.406  3.562   26.635  1.00 27.26  ? 112 LEU D CA  1 
ATOM   7674  C  C   . LEU D 1 112 ? 41.010  2.350   27.349  1.00 32.74  ? 112 LEU D C   1 
ATOM   7675  O  O   . LEU D 1 112 ? 42.127  1.935   27.064  1.00 39.63  ? 112 LEU D O   1 
ATOM   7676  C  CB  . LEU D 1 112 ? 40.741  4.871   27.326  1.00 29.45  ? 112 LEU D CB  1 
ATOM   7677  C  CG  . LEU D 1 112 ? 42.241  5.199   27.403  1.00 35.50  ? 112 LEU D CG  1 
ATOM   7678  C  CD1 . LEU D 1 112 ? 42.771  5.257   25.998  1.00 39.95  ? 112 LEU D CD1 1 
ATOM   7679  C  CD2 . LEU D 1 112 ? 42.632  6.494   28.092  1.00 39.79  ? 112 LEU D CD2 1 
ATOM   7680  N  N   . ASP D 1 113 ? 40.290  1.759   28.283  1.00 33.04  ? 113 ASP D N   1 
ATOM   7681  C  CA  . ASP D 1 113 ? 40.871  0.747   29.143  1.00 35.04  ? 113 ASP D CA  1 
ATOM   7682  C  C   . ASP D 1 113 ? 41.222  -0.482  28.319  1.00 29.47  ? 113 ASP D C   1 
ATOM   7683  O  O   . ASP D 1 113 ? 42.185  -1.154  28.649  1.00 32.03  ? 113 ASP D O   1 
ATOM   7684  C  CB  . ASP D 1 113 ? 39.944  0.308   30.274  1.00 42.09  ? 113 ASP D CB  1 
ATOM   7685  C  CG  . ASP D 1 113 ? 38.561  -0.142  29.813  1.00 43.07  ? 113 ASP D CG  1 
ATOM   7686  O  OD1 . ASP D 1 113 ? 37.811  0.804   29.447  1.00 41.65  ? 113 ASP D OD1 1 
ATOM   7687  O  OD2 . ASP D 1 113 ? 38.265  -1.404  29.780  1.00 37.47  ? 113 ASP D OD2 1 
ATOM   7688  N  N   . LEU D 1 114 ? 40.428  -0.822  27.310  1.00 26.16  ? 114 LEU D N   1 
ATOM   7689  C  CA  . LEU D 1 114 ? 40.780  -1.936  26.444  1.00 29.58  ? 114 LEU D CA  1 
ATOM   7690  C  C   . LEU D 1 114 ? 42.089  -1.677  25.680  1.00 28.19  ? 114 LEU D C   1 
ATOM   7691  O  O   . LEU D 1 114 ? 42.899  -2.587  25.494  1.00 23.70  ? 114 LEU D O   1 
ATOM   7692  C  CB  . LEU D 1 114 ? 39.660  -2.197  25.440  1.00 32.79  ? 114 LEU D CB  1 
ATOM   7693  C  CG  . LEU D 1 114 ? 38.411  -2.876  25.992  1.00 34.28  ? 114 LEU D CG  1 
ATOM   7694  C  CD1 . LEU D 1 114 ? 37.340  -2.942  24.911  1.00 32.48  ? 114 LEU D CD1 1 
ATOM   7695  C  CD2 . LEU D 1 114 ? 38.769  -4.277  26.394  1.00 36.06  ? 114 LEU D CD2 1 
ATOM   7696  N  N   . CYS D 1 115 ? 42.240  -0.445  25.182  1.00 26.13  ? 115 CYS D N   1 
ATOM   7697  C  CA  . CYS D 1 115 ? 43.461  -0.006  24.541  1.00 27.69  ? 115 CYS D CA  1 
ATOM   7698  C  C   . CYS D 1 115 ? 44.626  -0.185  25.503  1.00 24.34  ? 115 CYS D C   1 
ATOM   7699  O  O   . CYS D 1 115 ? 45.669  -0.710  25.134  1.00 27.88  ? 115 CYS D O   1 
ATOM   7700  C  CB  . CYS D 1 115 ? 43.386  1.453   24.116  1.00 26.29  ? 115 CYS D CB  1 
ATOM   7701  S  SG  . CYS D 1 115 ? 42.134  1.690   22.835  1.00 25.38  ? 115 CYS D SG  1 
ATOM   7702  N  N   . PHE D 1 116 ? 44.435  0.255   26.733  1.00 20.07  ? 116 PHE D N   1 
ATOM   7703  C  CA  . PHE D 1 116 ? 45.518  0.261   27.696  1.00 21.49  ? 116 PHE D CA  1 
ATOM   7704  C  C   . PHE D 1 116 ? 45.890  -1.160  28.088  1.00 22.81  ? 116 PHE D C   1 
ATOM   7705  O  O   . PHE D 1 116 ? 47.045  -1.469  28.316  1.00 21.44  ? 116 PHE D O   1 
ATOM   7706  C  CB  . PHE D 1 116 ? 45.107  1.075   28.911  1.00 21.51  ? 116 PHE D CB  1 
ATOM   7707  C  CG  . PHE D 1 116 ? 46.252  1.384   29.844  1.00 21.50  ? 116 PHE D CG  1 
ATOM   7708  C  CD1 . PHE D 1 116 ? 46.969  2.552   29.688  1.00 25.42  ? 116 PHE D CD1 1 
ATOM   7709  C  CD2 . PHE D 1 116 ? 46.551  0.546   30.904  1.00 24.89  ? 116 PHE D CD2 1 
ATOM   7710  C  CE1 . PHE D 1 116 ? 48.013  2.872   30.557  1.00 27.15  ? 116 PHE D CE1 1 
ATOM   7711  C  CE2 . PHE D 1 116 ? 47.558  0.870   31.798  1.00 27.51  ? 116 PHE D CE2 1 
ATOM   7712  C  CZ  . PHE D 1 116 ? 48.301  2.031   31.620  1.00 28.53  ? 116 PHE D CZ  1 
ATOM   7713  N  N   . ALA D 1 117 ? 44.906  -2.040  28.176  1.00 25.13  ? 117 ALA D N   1 
ATOM   7714  C  CA  . ALA D 1 117 ? 45.173  -3.405  28.596  1.00 27.37  ? 117 ALA D CA  1 
ATOM   7715  C  C   . ALA D 1 117 ? 46.031  -4.084  27.542  1.00 27.00  ? 117 ALA D C   1 
ATOM   7716  O  O   . ALA D 1 117 ? 46.999  -4.747  27.890  1.00 31.70  ? 117 ALA D O   1 
ATOM   7717  C  CB  . ALA D 1 117 ? 43.880  -4.156  28.820  1.00 29.41  ? 117 ALA D CB  1 
ATOM   7718  N  N   . LEU D 1 118 ? 45.694  -3.877  26.263  1.00 26.14  ? 118 LEU D N   1 
ATOM   7719  C  CA  . LEU D 1 118 ? 46.459  -4.460  25.183  1.00 24.74  ? 118 LEU D CA  1 
ATOM   7720  C  C   . LEU D 1 118 ? 47.872  -3.840  25.117  1.00 26.96  ? 118 LEU D C   1 
ATOM   7721  O  O   . LEU D 1 118 ? 48.879  -4.536  24.948  1.00 25.54  ? 118 LEU D O   1 
ATOM   7722  C  CB  . LEU D 1 118 ? 45.681  -4.323  23.890  1.00 22.48  ? 118 LEU D CB  1 
ATOM   7723  C  CG  . LEU D 1 118 ? 46.358  -5.025  22.722  1.00 27.16  ? 118 LEU D CG  1 
ATOM   7724  C  CD1 . LEU D 1 118 ? 46.688  -6.430  23.088  1.00 28.82  ? 118 LEU D CD1 1 
ATOM   7725  C  CD2 . LEU D 1 118 ? 45.561  -5.083  21.417  1.00 30.68  ? 118 LEU D CD2 1 
ATOM   7726  N  N   . ALA D 1 119 ? 47.964  -2.521  25.244  1.00 25.13  ? 119 ALA D N   1 
ATOM   7727  C  CA  . ALA D 1 119 ? 49.263  -1.872  25.228  1.00 25.91  ? 119 ALA D CA  1 
ATOM   7728  C  C   . ALA D 1 119 ? 50.157  -2.410  26.363  1.00 26.61  ? 119 ALA D C   1 
ATOM   7729  O  O   . ALA D 1 119 ? 51.358  -2.615  26.176  1.00 26.03  ? 119 ALA D O   1 
ATOM   7730  C  CB  . ALA D 1 119 ? 49.087  -0.378  25.305  1.00 25.13  ? 119 ALA D CB  1 
ATOM   7731  N  N   . THR D 1 120 ? 49.579  -2.603  27.547  1.00 23.84  ? 120 THR D N   1 
ATOM   7732  C  CA  . THR D 1 120 ? 50.301  -3.152  28.672  1.00 24.68  ? 120 THR D CA  1 
ATOM   7733  C  C   . THR D 1 120 ? 50.860  -4.520  28.320  1.00 23.38  ? 120 THR D C   1 
ATOM   7734  O  O   . THR D 1 120 ? 52.003  -4.797  28.641  1.00 24.03  ? 120 THR D O   1 
ATOM   7735  C  CB  . THR D 1 120 ? 49.380  -3.297  29.873  1.00 27.27  ? 120 THR D CB  1 
ATOM   7736  O  OG1 . THR D 1 120 ? 49.034  -2.005  30.322  1.00 24.86  ? 120 THR D OG1 1 
ATOM   7737  C  CG2 . THR D 1 120 ? 50.143  -3.823  31.063  1.00 34.19  ? 120 THR D CG2 1 
ATOM   7738  N  N   . GLU D 1 121 ? 50.047  -5.383  27.725  1.00 22.58  ? 121 GLU D N   1 
ATOM   7739  C  CA  . GLU D 1 121 ? 50.515  -6.723  27.388  1.00 25.61  ? 121 GLU D CA  1 
ATOM   7740  C  C   . GLU D 1 121 ? 51.664  -6.641  26.374  1.00 28.41  ? 121 GLU D C   1 
ATOM   7741  O  O   . GLU D 1 121 ? 52.637  -7.361  26.465  1.00 23.75  ? 121 GLU D O   1 
ATOM   7742  C  CB  . GLU D 1 121 ? 49.464  -7.636  26.753  1.00 29.60  ? 121 GLU D CB  1 
ATOM   7743  C  CG  . GLU D 1 121 ? 48.379  -8.087  27.716  1.00 36.28  ? 121 GLU D CG  1 
ATOM   7744  C  CD  . GLU D 1 121 ? 48.795  -9.071  28.784  1.00 38.79  ? 121 GLU D CD  1 
ATOM   7745  O  OE1 . GLU D 1 121 ? 49.848  -9.732  28.587  1.00 39.95  ? 121 GLU D OE1 1 
ATOM   7746  O  OE2 . GLU D 1 121 ? 48.049  -9.122  29.792  1.00 38.42  ? 121 GLU D OE2 1 
ATOM   7747  N  N   . ILE D 1 122 ? 51.521  -5.789  25.359  1.00 33.04  ? 122 ILE D N   1 
ATOM   7748  C  CA  . ILE D 1 122 ? 52.528  -5.698  24.320  1.00 30.36  ? 122 ILE D CA  1 
ATOM   7749  C  C   . ILE D 1 122 ? 53.822  -5.175  24.922  1.00 27.32  ? 122 ILE D C   1 
ATOM   7750  O  O   . ILE D 1 122 ? 54.833  -5.824  24.771  1.00 27.20  ? 122 ILE D O   1 
ATOM   7751  C  CB  . ILE D 1 122 ? 51.992  -4.850  23.152  1.00 32.91  ? 122 ILE D CB  1 
ATOM   7752  C  CG1 . ILE D 1 122 ? 50.960  -5.684  22.373  1.00 34.30  ? 122 ILE D CG1 1 
ATOM   7753  C  CG2 . ILE D 1 122 ? 53.107  -4.344  22.244  1.00 33.03  ? 122 ILE D CG2 1 
ATOM   7754  C  CD1 . ILE D 1 122 ? 50.084  -4.884  21.440  1.00 37.95  ? 122 ILE D CD1 1 
ATOM   7755  N  N   . MET D 1 123 ? 53.795  -4.055  25.639  1.00 27.35  ? 123 MET D N   1 
ATOM   7756  C  CA  . MET D 1 123 ? 55.016  -3.501  26.200  1.00 29.70  ? 123 MET D CA  1 
ATOM   7757  C  C   . MET D 1 123 ? 55.642  -4.387  27.275  1.00 31.27  ? 123 MET D C   1 
ATOM   7758  O  O   . MET D 1 123 ? 56.845  -4.309  27.516  1.00 34.84  ? 123 MET D O   1 
ATOM   7759  C  CB  . MET D 1 123 ? 54.759  -2.148  26.831  1.00 33.64  ? 123 MET D CB  1 
ATOM   7760  C  CG  . MET D 1 123 ? 54.616  -1.091  25.752  1.00 49.84  ? 123 MET D CG  1 
ATOM   7761  S  SD  . MET D 1 123 ? 56.129  -0.743  24.818  1.00 52.52  ? 123 MET D SD  1 
ATOM   7762  C  CE  . MET D 1 123 ? 57.273  -0.587  26.194  1.00 59.97  ? 123 MET D CE  1 
ATOM   7763  N  N   . GLY D 1 124 ? 54.819  -5.202  27.930  1.00 30.05  ? 124 GLY D N   1 
ATOM   7764  C  CA  . GLY D 1 124 ? 55.292  -6.169  28.898  1.00 27.63  ? 124 GLY D CA  1 
ATOM   7765  C  C   . GLY D 1 124 ? 56.174  -7.211  28.233  1.00 25.65  ? 124 GLY D C   1 
ATOM   7766  O  O   . GLY D 1 124 ? 57.160  -7.581  28.807  1.00 33.67  ? 124 GLY D O   1 
ATOM   7767  N  N   . ARG D 1 125 ? 55.837  -7.652  27.024  1.00 24.35  ? 125 ARG D N   1 
ATOM   7768  C  CA  . ARG D 1 125 ? 56.607  -8.632  26.300  1.00 27.53  ? 125 ARG D CA  1 
ATOM   7769  C  C   . ARG D 1 125 ? 57.858  -8.014  25.687  1.00 33.50  ? 125 ARG D C   1 
ATOM   7770  O  O   . ARG D 1 125 ? 58.764  -8.735  25.277  1.00 37.26  ? 125 ARG D O   1 
ATOM   7771  C  CB  . ARG D 1 125 ? 55.778  -9.232  25.182  1.00 28.91  ? 125 ARG D CB  1 
ATOM   7772  C  CG  . ARG D 1 125 ? 54.602  -10.024 25.743  1.00 37.88  ? 125 ARG D CG  1 
ATOM   7773  C  CD  . ARG D 1 125 ? 54.847  -11.524 25.799  1.00 44.10  ? 125 ARG D CD  1 
ATOM   7774  N  NE  . ARG D 1 125 ? 54.219  -12.239 24.680  1.00 48.23  ? 125 ARG D NE  1 
ATOM   7775  C  CZ  . ARG D 1 125 ? 54.883  -12.668 23.603  1.00 53.25  ? 125 ARG D CZ  1 
ATOM   7776  N  NH1 . ARG D 1 125 ? 56.199  -12.694 23.565  1.00 51.09  ? 125 ARG D NH1 1 
ATOM   7777  N  NH2 . ARG D 1 125 ? 54.233  -13.047 22.520  1.00 65.07  ? 125 ARG D NH2 1 
ATOM   7778  N  N   . LEU D 1 126 ? 57.894  -6.688  25.568  1.00 34.05  ? 126 LEU D N   1 
ATOM   7779  C  CA  . LEU D 1 126 ? 58.984  -6.043  24.860  1.00 35.38  ? 126 LEU D CA  1 
ATOM   7780  C  C   . LEU D 1 126 ? 59.925  -5.379  25.849  1.00 41.97  ? 126 LEU D C   1 
ATOM   7781  O  O   . LEU D 1 126 ? 60.907  -4.835  25.357  1.00 38.21  ? 126 LEU D O   1 
ATOM   7782  C  CB  . LEU D 1 126 ? 58.476  -5.000  23.865  1.00 34.42  ? 126 LEU D CB  1 
ATOM   7783  C  CG  . LEU D 1 126 ? 57.685  -5.538  22.657  1.00 35.70  ? 126 LEU D CG  1 
ATOM   7784  C  CD1 . LEU D 1 126 ? 57.203  -4.387  21.762  1.00 35.82  ? 126 LEU D CD1 1 
ATOM   7785  C  CD2 . LEU D 1 126 ? 58.342  -6.609  21.798  1.00 31.86  ? 126 LEU D CD2 1 
ATOM   7786  N  N   . ARG D 1 127 ? 59.609  -5.369  27.171  1.00 45.94  ? 127 ARG D N   1 
ATOM   7787  C  CA  . ARG D 1 127 ? 60.481  -4.823  28.212  1.00 49.75  ? 127 ARG D CA  1 
ATOM   7788  C  C   . ARG D 1 127 ? 61.907  -5.327  27.939  1.00 48.13  ? 127 ARG D C   1 
ATOM   7789  O  O   . ARG D 1 127 ? 62.138  -6.522  27.705  1.00 44.19  ? 127 ARG D O   1 
ATOM   7790  C  CB  . ARG D 1 127 ? 60.152  -5.259  29.653  1.00 58.39  ? 127 ARG D CB  1 
ATOM   7791  C  CG  . ARG D 1 127 ? 59.077  -4.590  30.497  1.00 75.53  ? 127 ARG D CG  1 
ATOM   7792  C  CD  . ARG D 1 127 ? 59.171  -3.073  30.650  1.00 85.09  ? 127 ARG D CD  1 
ATOM   7793  N  NE  . ARG D 1 127 ? 57.848  -2.567  31.061  1.00 97.87  ? 127 ARG D NE  1 
ATOM   7794  C  CZ  . ARG D 1 127 ? 57.008  -1.746  30.391  1.00 94.66  ? 127 ARG D CZ  1 
ATOM   7795  N  NH1 . ARG D 1 127 ? 55.767  -1.556  30.807  1.00 88.58  ? 127 ARG D NH1 1 
ATOM   7796  N  NH2 . ARG D 1 127 ? 57.378  -1.149  29.278  1.00 94.53  ? 127 ARG D NH2 1 
ATOM   7797  N  N   . GLY D 1 128 ? 62.876  -4.413  27.883  1.00 40.07  ? 128 GLY D N   1 
ATOM   7798  C  CA  . GLY D 1 128 ? 64.244  -4.856  27.684  1.00 43.06  ? 128 GLY D CA  1 
ATOM   7799  C  C   . GLY D 1 128 ? 64.687  -4.797  26.228  1.00 44.37  ? 128 GLY D C   1 
ATOM   7800  O  O   . GLY D 1 128 ? 65.872  -4.600  25.972  1.00 51.77  ? 128 GLY D O   1 
ATOM   7801  N  N   . ALA D 1 129 ? 63.762  -4.910  25.268  1.00 37.59  ? 129 ALA D N   1 
ATOM   7802  C  CA  . ALA D 1 129 ? 64.138  -4.956  23.864  1.00 31.81  ? 129 ALA D CA  1 
ATOM   7803  C  C   . ALA D 1 129 ? 63.961  -3.621  23.127  1.00 32.50  ? 129 ALA D C   1 
ATOM   7804  O  O   . ALA D 1 129 ? 64.491  -3.499  22.022  1.00 37.95  ? 129 ALA D O   1 
ATOM   7805  C  CB  . ALA D 1 129 ? 63.363  -6.043  23.175  1.00 27.39  ? 129 ALA D CB  1 
ATOM   7806  N  N   . VAL D 1 130 ? 63.157  -2.683  23.663  1.00 28.34  ? 130 VAL D N   1 
ATOM   7807  C  CA  . VAL D 1 130 ? 62.740  -1.530  22.879  1.00 27.62  ? 130 VAL D CA  1 
ATOM   7808  C  C   . VAL D 1 130 ? 62.811  -0.285  23.743  1.00 30.15  ? 130 VAL D C   1 
ATOM   7809  O  O   . VAL D 1 130 ? 62.874  -0.383  24.940  1.00 27.47  ? 130 VAL D O   1 
ATOM   7810  C  CB  . VAL D 1 130 ? 61.323  -1.691  22.279  1.00 29.48  ? 130 VAL D CB  1 
ATOM   7811  C  CG1 . VAL D 1 130 ? 61.163  -2.971  21.471  1.00 28.01  ? 130 VAL D CG1 1 
ATOM   7812  C  CG2 . VAL D 1 130 ? 60.244  -1.640  23.345  1.00 29.77  ? 130 VAL D CG2 1 
ATOM   7813  N  N   . THR D 1 131 ? 62.784  0.885   23.113  1.00 34.50  ? 131 THR D N   1 
ATOM   7814  C  CA  . THR D 1 131 ? 62.807  2.153   23.822  1.00 40.97  ? 131 THR D CA  1 
ATOM   7815  C  C   . THR D 1 131 ? 61.603  2.954   23.338  1.00 37.30  ? 131 THR D C   1 
ATOM   7816  O  O   . THR D 1 131 ? 61.410  3.130   22.134  1.00 31.67  ? 131 THR D O   1 
ATOM   7817  C  CB  . THR D 1 131 ? 64.136  2.887   23.582  1.00 42.37  ? 131 THR D CB  1 
ATOM   7818  O  OG1 . THR D 1 131 ? 65.134  2.084   24.217  1.00 48.27  ? 131 THR D OG1 1 
ATOM   7819  C  CG2 . THR D 1 131 ? 64.128  4.307   24.128  1.00 34.62  ? 131 THR D CG2 1 
ATOM   7820  N  N   . PRO D 1 132 ? 60.730  3.433   24.255  1.00 36.12  ? 132 PRO D N   1 
ATOM   7821  C  CA  . PRO D 1 132 ? 59.509  4.107   23.825  1.00 35.02  ? 132 PRO D CA  1 
ATOM   7822  C  C   . PRO D 1 132 ? 59.921  5.461   23.276  1.00 31.90  ? 132 PRO D C   1 
ATOM   7823  O  O   . PRO D 1 132 ? 60.744  6.118   23.870  1.00 32.86  ? 132 PRO D O   1 
ATOM   7824  C  CB  . PRO D 1 132 ? 58.665  4.176   25.093  1.00 37.30  ? 132 PRO D CB  1 
ATOM   7825  C  CG  . PRO D 1 132 ? 59.358  3.232   26.060  1.00 32.99  ? 132 PRO D CG  1 
ATOM   7826  C  CD  . PRO D 1 132 ? 60.836  3.334   25.718  1.00 34.84  ? 132 PRO D CD  1 
ATOM   7827  N  N   . GLN D 1 133 ? 59.375  5.839   22.125  1.00 33.78  ? 133 GLN D N   1 
ATOM   7828  C  CA  . GLN D 1 133 ? 59.604  7.162   21.562  1.00 33.69  ? 133 GLN D CA  1 
ATOM   7829  C  C   . GLN D 1 133 ? 58.378  8.063   21.679  1.00 26.85  ? 133 GLN D C   1 
ATOM   7830  O  O   . GLN D 1 133 ? 58.527  9.253   21.739  1.00 26.79  ? 133 GLN D O   1 
ATOM   7831  C  CB  . GLN D 1 133 ? 59.791  7.108   20.045  1.00 45.84  ? 133 GLN D CB  1 
ATOM   7832  C  CG  . GLN D 1 133 ? 61.018  6.340   19.594  1.00 49.15  ? 133 GLN D CG  1 
ATOM   7833  C  CD  . GLN D 1 133 ? 62.267  6.955   20.169  1.00 48.94  ? 133 GLN D CD  1 
ATOM   7834  O  OE1 . GLN D 1 133 ? 62.429  8.182   20.140  1.00 51.05  ? 133 GLN D OE1 1 
ATOM   7835  N  NE2 . GLN D 1 133 ? 63.131  6.113   20.715  1.00 48.00  ? 133 GLN D NE2 1 
ATOM   7836  N  N   . ASP D 1 134 ? 57.168  7.526   21.555  1.00 24.73  ? 134 ASP D N   1 
ATOM   7837  C  CA  . ASP D 1 134 ? 55.958  8.338   21.590  1.00 27.53  ? 134 ASP D CA  1 
ATOM   7838  C  C   . ASP D 1 134 ? 54.843  7.464   22.147  1.00 24.61  ? 134 ASP D C   1 
ATOM   7839  O  O   . ASP D 1 134 ? 54.777  6.269   21.825  1.00 24.25  ? 134 ASP D O   1 
ATOM   7840  C  CB  . ASP D 1 134 ? 55.588  8.933   20.233  1.00 27.00  ? 134 ASP D CB  1 
ATOM   7841  C  CG  . ASP D 1 134 ? 54.708  10.185  20.287  1.00 28.16  ? 134 ASP D CG  1 
ATOM   7842  O  OD1 . ASP D 1 134 ? 54.618  10.785  21.375  1.00 25.20  ? 134 ASP D OD1 1 
ATOM   7843  O  OD2 . ASP D 1 134 ? 54.167  10.592  19.243  1.00 25.37  ? 134 ASP D OD2 1 
ATOM   7844  N  N   . GLU D 1 135 ? 54.053  8.064   23.051  1.00 22.80  ? 135 GLU D N   1 
ATOM   7845  C  CA  . GLU D 1 135 ? 52.854  7.434   23.545  1.00 22.93  ? 135 GLU D CA  1 
ATOM   7846  C  C   . GLU D 1 135 ? 51.765  8.489   23.609  1.00 20.89  ? 135 GLU D C   1 
ATOM   7847  O  O   . GLU D 1 135 ? 51.935  9.464   24.287  1.00 20.90  ? 135 GLU D O   1 
ATOM   7848  C  CB  . GLU D 1 135 ? 53.108  6.807   24.907  1.00 24.83  ? 135 GLU D CB  1 
ATOM   7849  C  CG  . GLU D 1 135 ? 51.873  6.046   25.385  1.00 31.24  ? 135 GLU D CG  1 
ATOM   7850  C  CD  . GLU D 1 135 ? 52.064  5.363   26.720  1.00 33.69  ? 135 GLU D CD  1 
ATOM   7851  O  OE1 . GLU D 1 135 ? 53.204  5.405   27.203  1.00 33.67  ? 135 GLU D OE1 1 
ATOM   7852  O  OE2 . GLU D 1 135 ? 51.081  4.842   27.270  1.00 34.66  ? 135 GLU D OE2 1 
ATOM   7853  N  N   . VAL D 1 136 ? 50.678  8.321   22.856  1.00 21.43  ? 136 VAL D N   1 
ATOM   7854  C  CA  . VAL D 1 136 ? 49.565  9.261   22.885  1.00 20.73  ? 136 VAL D CA  1 
ATOM   7855  C  C   . VAL D 1 136 ? 48.276  8.491   23.163  1.00 19.90  ? 136 VAL D C   1 
ATOM   7856  O  O   . VAL D 1 136 ? 48.017  7.407   22.583  1.00 20.58  ? 136 VAL D O   1 
ATOM   7857  C  CB  . VAL D 1 136 ? 49.514  9.990   21.540  1.00 24.92  ? 136 VAL D CB  1 
ATOM   7858  C  CG1 . VAL D 1 136 ? 48.257  10.818  21.338  1.00 27.55  ? 136 VAL D CG1 1 
ATOM   7859  C  CG2 . VAL D 1 136 ? 50.738  10.871  21.339  1.00 29.20  ? 136 VAL D CG2 1 
ATOM   7860  N  N   . HIS D 1 137 ? 47.495  9.050   24.093  1.00 19.42  ? 137 HIS D N   1 
ATOM   7861  C  CA  . HIS D 1 137 ? 46.166  8.552   24.405  1.00 21.12  ? 137 HIS D CA  1 
ATOM   7862  C  C   . HIS D 1 137 ? 45.190  9.532   23.779  1.00 22.79  ? 137 HIS D C   1 
ATOM   7863  O  O   . HIS D 1 137 ? 45.158  10.707  24.158  1.00 22.69  ? 137 HIS D O   1 
ATOM   7864  C  CB  . HIS D 1 137 ? 45.951  8.429   25.918  1.00 21.81  ? 137 HIS D CB  1 
ATOM   7865  C  CG  . HIS D 1 137 ? 46.857  7.465   26.575  1.00 23.70  ? 137 HIS D CG  1 
ATOM   7866  N  ND1 . HIS D 1 137 ? 46.712  7.134   27.889  1.00 26.18  ? 137 HIS D ND1 1 
ATOM   7867  C  CD2 . HIS D 1 137 ? 47.971  6.824   26.140  1.00 27.68  ? 137 HIS D CD2 1 
ATOM   7868  C  CE1 . HIS D 1 137 ? 47.717  6.317   28.227  1.00 31.78  ? 137 HIS D CE1 1 
ATOM   7869  N  NE2 . HIS D 1 137 ? 48.502  6.114   27.174  1.00 30.32  ? 137 HIS D NE2 1 
ATOM   7870  N  N   . GLY D 1 138 ? 44.480  9.045   22.762  1.00 26.57  ? 138 GLY D N   1 
ATOM   7871  C  CA  . GLY D 1 138 ? 43.589  9.899   21.993  1.00 27.65  ? 138 GLY D CA  1 
ATOM   7872  C  C   . GLY D 1 138 ? 42.140  9.646   22.383  1.00 24.85  ? 138 GLY D C   1 
ATOM   7873  O  O   . GLY D 1 138 ? 41.811  8.541   22.762  1.00 20.91  ? 138 GLY D O   1 
ATOM   7874  N  N   . PHE D 1 139 ? 41.298  10.669  22.238  1.00 24.81  ? 139 PHE D N   1 
ATOM   7875  C  CA  . PHE D 1 139 ? 39.878  10.548  22.488  1.00 25.43  ? 139 PHE D CA  1 
ATOM   7876  C  C   . PHE D 1 139 ? 39.116  11.326  21.425  1.00 30.27  ? 139 PHE D C   1 
ATOM   7877  O  O   . PHE D 1 139 ? 39.503  12.455  21.127  1.00 37.67  ? 139 PHE D O   1 
ATOM   7878  C  CB  . PHE D 1 139 ? 39.650  11.085  23.899  1.00 24.87  ? 139 PHE D CB  1 
ATOM   7879  C  CG  . PHE D 1 139 ? 40.202  12.462  24.198  1.00 24.48  ? 139 PHE D CG  1 
ATOM   7880  C  CD1 . PHE D 1 139 ? 39.499  13.602  23.832  1.00 26.02  ? 139 PHE D CD1 1 
ATOM   7881  C  CD2 . PHE D 1 139 ? 41.408  12.619  24.856  1.00 27.38  ? 139 PHE D CD2 1 
ATOM   7882  C  CE1 . PHE D 1 139 ? 39.995  14.883  24.118  1.00 31.90  ? 139 PHE D CE1 1 
ATOM   7883  C  CE2 . PHE D 1 139 ? 41.890  13.895  25.172  1.00 28.91  ? 139 PHE D CE2 1 
ATOM   7884  C  CZ  . PHE D 1 139 ? 41.194  15.036  24.785  1.00 30.81  ? 139 PHE D CZ  1 
ATOM   7885  N  N   . LYS D 1 140 ? 38.024  10.759  20.898  1.00 29.77  ? 140 LYS D N   1 
ATOM   7886  C  CA  . LYS D 1 140 ? 37.217  11.481  19.921  1.00 35.11  ? 140 LYS D CA  1 
ATOM   7887  C  C   . LYS D 1 140 ? 36.309  12.424  20.702  1.00 28.01  ? 140 LYS D C   1 
ATOM   7888  O  O   . LYS D 1 140 ? 35.869  12.060  21.770  1.00 21.05  ? 140 LYS D O   1 
ATOM   7889  C  CB  . LYS D 1 140 ? 36.576  10.499  18.930  1.00 48.34  ? 140 LYS D CB  1 
ATOM   7890  C  CG  . LYS D 1 140 ? 36.488  10.991  17.447  1.00 65.35  ? 140 LYS D CG  1 
ATOM   7891  C  CD  . LYS D 1 140 ? 37.698  11.536  16.681  1.00 70.69  ? 140 LYS D CD  1 
ATOM   7892  C  CE  . LYS D 1 140 ? 37.461  12.533  15.540  1.00 67.82  ? 140 LYS D CE  1 
ATOM   7893  N  NZ  . LYS D 1 140 ? 37.148  11.904  14.250  1.00 65.62  ? 140 LYS D NZ  1 
ATOM   7894  N  N   . TYR D 1 141 ? 36.142  13.666  20.223  1.00 31.48  ? 141 TYR D N   1 
ATOM   7895  C  CA  . TYR D 1 141 ? 35.106  14.557  20.702  1.00 36.40  ? 141 TYR D CA  1 
ATOM   7896  C  C   . TYR D 1 141 ? 33.732  14.060  20.256  1.00 49.15  ? 141 TYR D C   1 
ATOM   7897  O  O   . TYR D 1 141 ? 33.613  13.207  19.398  1.00 57.85  ? 141 TYR D O   1 
ATOM   7898  C  CB  . TYR D 1 141 ? 35.328  15.949  20.133  1.00 41.26  ? 141 TYR D CB  1 
ATOM   7899  C  CG  . TYR D 1 141 ? 36.165  16.821  21.040  1.00 42.27  ? 141 TYR D CG  1 
ATOM   7900  C  CD1 . TYR D 1 141 ? 35.539  17.573  22.003  1.00 49.78  ? 141 TYR D CD1 1 
ATOM   7901  C  CD2 . TYR D 1 141 ? 37.533  16.875  20.967  1.00 47.69  ? 141 TYR D CD2 1 
ATOM   7902  C  CE1 . TYR D 1 141 ? 36.251  18.383  22.861  1.00 53.46  ? 141 TYR D CE1 1 
ATOM   7903  C  CE2 . TYR D 1 141 ? 38.264  17.651  21.841  1.00 50.89  ? 141 TYR D CE2 1 
ATOM   7904  C  CZ  . TYR D 1 141 ? 37.621  18.406  22.792  1.00 52.37  ? 141 TYR D CZ  1 
ATOM   7905  O  OH  . TYR D 1 141 ? 38.324  19.191  23.652  1.00 62.58  ? 141 TYR D OH  1 
ATOM   7906  N  N   . PHE D 1 142 ? 32.672  14.554  20.873  1.00 62.58  ? 142 PHE D N   1 
ATOM   7907  C  CA  . PHE D 1 142 ? 31.489  13.713  20.931  1.00 69.65  ? 142 PHE D CA  1 
ATOM   7908  C  C   . PHE D 1 142 ? 30.752  13.759  19.585  1.00 61.00  ? 142 PHE D C   1 
ATOM   7909  O  O   . PHE D 1 142 ? 29.975  12.839  19.335  1.00 66.85  ? 142 PHE D O   1 
ATOM   7910  C  CB  . PHE D 1 142 ? 30.683  13.942  22.225  1.00 91.82  ? 142 PHE D CB  1 
ATOM   7911  C  CG  . PHE D 1 142 ? 29.639  15.036  22.150  1.00 91.01  ? 142 PHE D CG  1 
ATOM   7912  C  CD1 . PHE D 1 142 ? 30.005  16.369  22.349  1.00 93.49  ? 142 PHE D CD1 1 
ATOM   7913  C  CD2 . PHE D 1 142 ? 28.314  14.722  21.837  1.00 73.49  ? 142 PHE D CD2 1 
ATOM   7914  C  CE1 . PHE D 1 142 ? 29.045  17.371  22.272  1.00 101.46 ? 142 PHE D CE1 1 
ATOM   7915  C  CE2 . PHE D 1 142 ? 27.353  15.725  21.766  1.00 79.87  ? 142 PHE D CE2 1 
ATOM   7916  C  CZ  . PHE D 1 142 ? 27.718  17.048  21.979  1.00 92.92  ? 142 PHE D CZ  1 
ATOM   7917  N  N   . ASP D 1 143 ? 31.004  14.726  18.680  1.00 40.79  ? 143 ASP D N   1 
ATOM   7918  C  CA  . ASP D 1 143 ? 30.384  14.590  17.357  1.00 41.99  ? 143 ASP D CA  1 
ATOM   7919  C  C   . ASP D 1 143 ? 31.408  14.476  16.246  1.00 37.83  ? 143 ASP D C   1 
ATOM   7920  O  O   . ASP D 1 143 ? 31.312  15.152  15.232  1.00 41.33  ? 143 ASP D O   1 
ATOM   7921  C  CB  . ASP D 1 143 ? 29.420  15.703  17.009  1.00 56.51  ? 143 ASP D CB  1 
ATOM   7922  C  CG  . ASP D 1 143 ? 29.828  17.061  17.541  1.00 64.99  ? 143 ASP D CG  1 
ATOM   7923  O  OD1 . ASP D 1 143 ? 30.714  17.120  18.473  1.00 48.60  ? 143 ASP D OD1 1 
ATOM   7924  O  OD2 . ASP D 1 143 ? 29.235  18.025  17.008  1.00 71.02  ? 143 ASP D OD2 1 
ATOM   7925  N  N   . GLU D 1 144 ? 32.352  13.565  16.439  1.00 28.93  ? 144 GLU D N   1 
ATOM   7926  C  CA  . GLU D 1 144 ? 33.466  13.318  15.552  1.00 26.38  ? 144 GLU D CA  1 
ATOM   7927  C  C   . GLU D 1 144 ? 34.264  14.588  15.229  1.00 22.77  ? 144 GLU D C   1 
ATOM   7928  O  O   . GLU D 1 144 ? 34.960  14.653  14.209  1.00 24.18  ? 144 GLU D O   1 
ATOM   7929  C  CB  . GLU D 1 144 ? 32.920  12.597  14.336  1.00 33.37  ? 144 GLU D CB  1 
ATOM   7930  C  CG  . GLU D 1 144 ? 32.275  11.257  14.673  1.00 38.08  ? 144 GLU D CG  1 
ATOM   7931  C  CD  . GLU D 1 144 ? 33.257  10.211  15.169  1.00 38.98  ? 144 GLU D CD  1 
ATOM   7932  O  OE1 . GLU D 1 144 ? 34.433  10.163  14.734  1.00 35.59  ? 144 GLU D OE1 1 
ATOM   7933  O  OE2 . GLU D 1 144 ? 32.797  9.430   16.019  1.00 41.15  ? 144 GLU D OE2 1 
ATOM   7934  N  N   . ARG D 1 145 ? 34.255  15.567  16.135  1.00 24.33  ? 145 ARG D N   1 
ATOM   7935  C  CA  . ARG D 1 145 ? 35.051  16.773  15.933  1.00 26.01  ? 145 ARG D CA  1 
ATOM   7936  C  C   . ARG D 1 145 ? 36.499  16.594  16.412  1.00 28.30  ? 145 ARG D C   1 
ATOM   7937  O  O   . ARG D 1 145 ? 36.842  15.733  17.253  1.00 24.27  ? 145 ARG D O   1 
ATOM   7938  C  CB  . ARG D 1 145 ? 34.364  17.966  16.608  1.00 26.05  ? 145 ARG D CB  1 
ATOM   7939  C  CG  . ARG D 1 145 ? 33.054  18.232  15.899  1.00 27.08  ? 145 ARG D CG  1 
ATOM   7940  C  CD  . ARG D 1 145 ? 32.501  19.577  16.255  1.00 26.89  ? 145 ARG D CD  1 
ATOM   7941  N  NE  . ARG D 1 145 ? 31.157  19.718  15.664  1.00 30.16  ? 145 ARG D NE  1 
ATOM   7942  C  CZ  . ARG D 1 145 ? 30.813  20.324  14.529  1.00 27.54  ? 145 ARG D CZ  1 
ATOM   7943  N  NH1 . ARG D 1 145 ? 31.659  21.049  13.833  1.00 29.86  ? 145 ARG D NH1 1 
ATOM   7944  N  NH2 . ARG D 1 145 ? 29.609  20.158  14.072  1.00 28.33  ? 145 ARG D NH2 1 
ATOM   7945  N  N   . ASP D 1 146 ? 37.361  17.447  15.849  1.00 26.65  ? 146 ASP D N   1 
ATOM   7946  C  CA  . ASP D 1 146 ? 38.754  17.449  16.246  1.00 27.12  ? 146 ASP D CA  1 
ATOM   7947  C  C   . ASP D 1 146 ? 38.935  18.668  17.128  1.00 24.88  ? 146 ASP D C   1 
ATOM   7948  O  O   . ASP D 1 146 ? 37.994  19.371  17.492  1.00 23.06  ? 146 ASP D O   1 
ATOM   7949  C  CB  . ASP D 1 146 ? 39.687  17.389  15.051  1.00 26.97  ? 146 ASP D CB  1 
ATOM   7950  C  CG  . ASP D 1 146 ? 39.513  18.569  14.085  1.00 29.18  ? 146 ASP D CG  1 
ATOM   7951  O  OD1 . ASP D 1 146 ? 39.082  19.630  14.550  1.00 28.12  ? 146 ASP D OD1 1 
ATOM   7952  O  OD2 . ASP D 1 146 ? 39.725  18.425  12.848  1.00 30.82  ? 146 ASP D OD2 1 
ATOM   7953  N  N   . MET D 1 147 ? 40.198  18.902  17.431  1.00 28.90  ? 147 MET D N   1 
ATOM   7954  C  CA  . MET D 1 147 ? 40.570  19.903  18.406  1.00 28.29  ? 147 MET D CA  1 
ATOM   7955  C  C   . MET D 1 147 ? 40.311  21.312  17.872  1.00 25.80  ? 147 MET D C   1 
ATOM   7956  O  O   . MET D 1 147 ? 40.214  22.243  18.637  1.00 23.74  ? 147 MET D O   1 
ATOM   7957  C  CB  . MET D 1 147 ? 42.038  19.640  18.753  1.00 33.63  ? 147 MET D CB  1 
ATOM   7958  C  CG  . MET D 1 147 ? 42.474  20.284  20.023  1.00 34.60  ? 147 MET D CG  1 
ATOM   7959  S  SD  . MET D 1 147 ? 41.545  19.674  21.430  1.00 33.36  ? 147 MET D SD  1 
ATOM   7960  C  CE  . MET D 1 147 ? 42.562  18.354  22.089  1.00 40.21  ? 147 MET D CE  1 
ATOM   7961  N  N   . LEU D 1 148 ? 40.185  21.497  16.561  1.00 23.21  ? 148 LEU D N   1 
ATOM   7962  C  CA  . LEU D 1 148 ? 39.889  22.807  16.003  1.00 24.36  ? 148 LEU D CA  1 
ATOM   7963  C  C   . LEU D 1 148 ? 38.379  23.009  15.886  1.00 22.61  ? 148 LEU D C   1 
ATOM   7964  O  O   . LEU D 1 148 ? 37.936  24.032  15.378  1.00 20.67  ? 148 LEU D O   1 
ATOM   7965  C  CB  . LEU D 1 148 ? 40.527  22.926  14.620  1.00 24.16  ? 148 LEU D CB  1 
ATOM   7966  C  CG  . LEU D 1 148 ? 42.036  22.730  14.526  1.00 23.98  ? 148 LEU D CG  1 
ATOM   7967  C  CD1 . LEU D 1 148 ? 42.466  22.809  13.045  1.00 22.96  ? 148 LEU D CD1 1 
ATOM   7968  C  CD2 . LEU D 1 148 ? 42.731  23.789  15.350  1.00 26.19  ? 148 LEU D CD2 1 
ATOM   7969  N  N   . GLY D 1 149 ? 37.585  22.015  16.271  1.00 21.85  ? 149 GLY D N   1 
ATOM   7970  C  CA  . GLY D 1 149 ? 36.155  22.219  16.307  1.00 23.41  ? 149 GLY D CA  1 
ATOM   7971  C  C   . GLY D 1 149 ? 35.442  21.830  15.010  1.00 24.32  ? 149 GLY D C   1 
ATOM   7972  O  O   . GLY D 1 149 ? 34.232  22.051  14.885  1.00 22.54  ? 149 GLY D O   1 
ATOM   7973  N  N   . PHE D 1 150 ? 36.163  21.218  14.058  1.00 24.37  ? 150 PHE D N   1 
ATOM   7974  C  CA  . PHE D 1 150 ? 35.583  20.767  12.798  1.00 22.51  ? 150 PHE D CA  1 
ATOM   7975  C  C   . PHE D 1 150 ? 35.355  19.262  12.823  1.00 23.94  ? 150 PHE D C   1 
ATOM   7976  O  O   . PHE D 1 150 ? 36.125  18.508  13.422  1.00 22.92  ? 150 PHE D O   1 
ATOM   7977  C  CB  . PHE D 1 150 ? 36.518  21.119  11.637  1.00 21.44  ? 150 PHE D CB  1 
ATOM   7978  C  CG  . PHE D 1 150 ? 36.340  22.559  11.194  1.00 19.09  ? 150 PHE D CG  1 
ATOM   7979  C  CD1 . PHE D 1 150 ? 36.799  23.599  11.975  1.00 17.92  ? 150 PHE D CD1 1 
ATOM   7980  C  CD2 . PHE D 1 150 ? 35.666  22.878  10.023  1.00 19.54  ? 150 PHE D CD2 1 
ATOM   7981  C  CE1 . PHE D 1 150 ? 36.594  24.904  11.572  1.00 18.43  ? 150 PHE D CE1 1 
ATOM   7982  C  CE2 . PHE D 1 150 ? 35.457  24.184  9.645   1.00 17.39  ? 150 PHE D CE2 1 
ATOM   7983  C  CZ  . PHE D 1 150 ? 35.913  25.192  10.414  1.00 16.96  ? 150 PHE D CZ  1 
ATOM   7984  N  N   . VAL D 1 151 ? 34.314  18.829  12.101  1.00 26.44  ? 151 VAL D N   1 
ATOM   7985  C  CA  . VAL D 1 151 ? 34.106  17.397  11.929  1.00 26.34  ? 151 VAL D CA  1 
ATOM   7986  C  C   . VAL D 1 151 ? 35.249  16.880  11.056  1.00 28.43  ? 151 VAL D C   1 
ATOM   7987  O  O   . VAL D 1 151 ? 35.585  17.499  10.026  1.00 31.92  ? 151 VAL D O   1 
ATOM   7988  C  CB  . VAL D 1 151 ? 32.759  17.093  11.271  1.00 24.20  ? 151 VAL D CB  1 
ATOM   7989  C  CG1 . VAL D 1 151 ? 32.552  15.601  11.138  1.00 23.06  ? 151 VAL D CG1 1 
ATOM   7990  C  CG2 . VAL D 1 151 ? 31.615  17.766  12.018  1.00 25.30  ? 151 VAL D CG2 1 
ATOM   7991  N  N   . ASP D 1 152 ? 35.792  15.734  11.491  1.00 27.04  ? 152 ASP D N   1 
ATOM   7992  C  CA  . ASP D 1 152 ? 37.057  15.225  11.010  1.00 27.36  ? 152 ASP D CA  1 
ATOM   7993  C  C   . ASP D 1 152 ? 36.841  13.758  10.689  1.00 24.23  ? 152 ASP D C   1 
ATOM   7994  O  O   . ASP D 1 152 ? 36.667  12.944  11.588  1.00 26.89  ? 152 ASP D O   1 
ATOM   7995  C  CB  . ASP D 1 152 ? 38.150  15.419  12.059  1.00 34.71  ? 152 ASP D CB  1 
ATOM   7996  C  CG  . ASP D 1 152 ? 39.604  15.205  11.615  1.00 36.49  ? 152 ASP D CG  1 
ATOM   7997  O  OD1 . ASP D 1 152 ? 39.834  14.216  10.886  1.00 33.85  ? 152 ASP D OD1 1 
ATOM   7998  O  OD2 . ASP D 1 152 ? 40.518  15.976  12.076  1.00 31.10  ? 152 ASP D OD2 1 
ATOM   7999  N  N   . GLY D 1 153 ? 36.858  13.447  9.396   1.00 22.26  ? 153 GLY D N   1 
ATOM   8000  C  CA  . GLY D 1 153 ? 36.697  12.085  8.922   1.00 22.06  ? 153 GLY D CA  1 
ATOM   8001  C  C   . GLY D 1 153 ? 35.703  11.962  7.770   1.00 24.98  ? 153 GLY D C   1 
ATOM   8002  O  O   . GLY D 1 153 ? 35.646  10.924  7.128   1.00 29.97  ? 153 GLY D O   1 
ATOM   8003  N  N   . THR D 1 154 ? 34.927  13.021  7.490   1.00 27.71  ? 154 THR D N   1 
ATOM   8004  C  CA  . THR D 1 154 ? 33.765  13.025  6.621   1.00 21.98  ? 154 THR D CA  1 
ATOM   8005  C  C   . THR D 1 154 ? 34.049  12.446  5.249   1.00 21.77  ? 154 THR D C   1 
ATOM   8006  O  O   . THR D 1 154 ? 33.279  11.630  4.765   1.00 21.69  ? 154 THR D O   1 
ATOM   8007  C  CB  . THR D 1 154 ? 33.306  14.456  6.464   1.00 24.51  ? 154 THR D CB  1 
ATOM   8008  O  OG1 . THR D 1 154 ? 33.165  14.966  7.781   1.00 23.78  ? 154 THR D OG1 1 
ATOM   8009  C  CG2 . THR D 1 154 ? 31.985  14.509  5.733   1.00 27.02  ? 154 THR D CG2 1 
ATOM   8010  N  N   . GLU D 1 155 ? 35.128  12.884  4.600   1.00 23.27  ? 155 GLU D N   1 
ATOM   8011  C  CA  . GLU D 1 155 ? 35.382  12.446  3.232   1.00 26.40  ? 155 GLU D CA  1 
ATOM   8012  C  C   . GLU D 1 155 ? 36.220  11.157  3.150   1.00 24.31  ? 155 GLU D C   1 
ATOM   8013  O  O   . GLU D 1 155 ? 36.673  10.784  2.087   1.00 22.40  ? 155 GLU D O   1 
ATOM   8014  C  CB  . GLU D 1 155 ? 35.947  13.562  2.357   1.00 28.77  ? 155 GLU D CB  1 
ATOM   8015  C  CG  . GLU D 1 155 ? 34.881  14.607  2.019   1.00 34.34  ? 155 GLU D CG  1 
ATOM   8016  C  CD  . GLU D 1 155 ? 33.667  14.175  1.191   1.00 35.63  ? 155 GLU D CD  1 
ATOM   8017  O  OE1 . GLU D 1 155 ? 33.876  13.446  0.226   1.00 32.26  ? 155 GLU D OE1 1 
ATOM   8018  O  OE2 . GLU D 1 155 ? 32.526  14.628  1.421   1.00 42.59  ? 155 GLU D OE2 1 
ATOM   8019  N  N   . ASN D 1 156 ? 36.403  10.426  4.239   1.00 23.65  ? 156 ASN D N   1 
ATOM   8020  C  CA  . ASN D 1 156 ? 37.116  9.169   4.126   1.00 24.95  ? 156 ASN D CA  1 
ATOM   8021  C  C   . ASN D 1 156 ? 36.381  8.196   3.216   1.00 26.48  ? 156 ASN D C   1 
ATOM   8022  O  O   . ASN D 1 156 ? 35.168  8.123   3.265   1.00 28.72  ? 156 ASN D O   1 
ATOM   8023  C  CB  . ASN D 1 156 ? 37.256  8.446   5.448   1.00 24.07  ? 156 ASN D CB  1 
ATOM   8024  C  CG  . ASN D 1 156 ? 38.496  8.851   6.182   1.00 24.56  ? 156 ASN D CG  1 
ATOM   8025  O  OD1 . ASN D 1 156 ? 39.548  9.108   5.597   1.00 30.00  ? 156 ASN D OD1 1 
ATOM   8026  N  ND2 . ASN D 1 156 ? 38.377  8.908   7.485   1.00 25.28  ? 156 ASN D ND2 1 
ATOM   8027  N  N   . PRO D 1 157 ? 37.087  7.368   2.429   1.00 26.85  ? 157 PRO D N   1 
ATOM   8028  C  CA  . PRO D 1 157 ? 36.414  6.360   1.617   1.00 29.75  ? 157 PRO D CA  1 
ATOM   8029  C  C   . PRO D 1 157 ? 35.808  5.275   2.501   1.00 32.33  ? 157 PRO D C   1 
ATOM   8030  O  O   . PRO D 1 157 ? 36.219  5.160   3.643   1.00 30.62  ? 157 PRO D O   1 
ATOM   8031  C  CB  . PRO D 1 157 ? 37.556  5.885   0.710   1.00 28.80  ? 157 PRO D CB  1 
ATOM   8032  C  CG  . PRO D 1 157 ? 38.789  6.065   1.549   1.00 29.16  ? 157 PRO D CG  1 
ATOM   8033  C  CD  . PRO D 1 157 ? 38.549  7.348   2.280   1.00 27.99  ? 157 PRO D CD  1 
ATOM   8034  N  N   . THR D 1 158 ? 34.799  4.550   1.985   1.00 38.84  ? 158 THR D N   1 
ATOM   8035  C  CA  . THR D 1 158 ? 34.221  3.384   2.662   1.00 41.46  ? 158 THR D CA  1 
ATOM   8036  C  C   . THR D 1 158 ? 34.030  2.224   1.673   1.00 42.38  ? 158 THR D C   1 
ATOM   8037  O  O   . THR D 1 158 ? 34.103  2.384   0.448   1.00 39.19  ? 158 THR D O   1 
ATOM   8038  C  CB  . THR D 1 158 ? 32.894  3.716   3.343   1.00 37.57  ? 158 THR D CB  1 
ATOM   8039  O  OG1 . THR D 1 158 ? 32.111  4.208   2.261   1.00 33.05  ? 158 THR D OG1 1 
ATOM   8040  C  CG2 . THR D 1 158 ? 33.050  4.699   4.488   1.00 37.03  ? 158 THR D CG2 1 
ATOM   8041  N  N   . GLY D 1 159 ? 33.792  1.033   2.240   1.00 42.95  ? 159 GLY D N   1 
ATOM   8042  C  CA  . GLY D 1 159 ? 33.534  -0.167  1.463   1.00 40.04  ? 159 GLY D CA  1 
ATOM   8043  C  C   . GLY D 1 159 ? 34.681  -0.452  0.494   1.00 38.00  ? 159 GLY D C   1 
ATOM   8044  O  O   . GLY D 1 159 ? 35.853  -0.437  0.861   1.00 36.17  ? 159 GLY D O   1 
ATOM   8045  N  N   . ALA D 1 160 ? 34.318  -0.710  -0.759  1.00 39.91  ? 160 ALA D N   1 
ATOM   8046  C  CA  . ALA D 1 160 ? 35.241  -1.204  -1.772  1.00 36.46  ? 160 ALA D CA  1 
ATOM   8047  C  C   . ALA D 1 160 ? 36.195  -0.091  -2.134  1.00 39.10  ? 160 ALA D C   1 
ATOM   8048  O  O   . ALA D 1 160 ? 37.345  -0.377  -2.429  1.00 42.85  ? 160 ALA D O   1 
ATOM   8049  C  CB  . ALA D 1 160 ? 34.526  -1.685  -3.027  1.00 36.06  ? 160 ALA D CB  1 
ATOM   8050  N  N   . ALA D 1 161 ? 35.734  1.168   -2.097  1.00 44.38  ? 161 ALA D N   1 
ATOM   8051  C  CA  . ALA D 1 161 ? 36.608  2.300   -2.412  1.00 46.29  ? 161 ALA D CA  1 
ATOM   8052  C  C   . ALA D 1 161 ? 37.785  2.330   -1.434  1.00 42.80  ? 161 ALA D C   1 
ATOM   8053  O  O   . ALA D 1 161 ? 38.921  2.612   -1.825  1.00 42.70  ? 161 ALA D O   1 
ATOM   8054  C  CB  . ALA D 1 161 ? 35.848  3.637   -2.411  1.00 40.92  ? 161 ALA D CB  1 
ATOM   8055  N  N   . ALA D 1 162 ? 37.487  2.023   -0.164  1.00 34.69  ? 162 ALA D N   1 
ATOM   8056  C  CA  . ALA D 1 162 ? 38.500  2.045   0.871   1.00 42.62  ? 162 ALA D CA  1 
ATOM   8057  C  C   . ALA D 1 162 ? 39.504  0.895   0.688   1.00 43.10  ? 162 ALA D C   1 
ATOM   8058  O  O   . ALA D 1 162 ? 40.728  1.120   0.727   1.00 47.85  ? 162 ALA D O   1 
ATOM   8059  C  CB  . ALA D 1 162 ? 37.825  2.057   2.228   1.00 39.52  ? 162 ALA D CB  1 
ATOM   8060  N  N   . ARG D 1 163 ? 38.987  -0.323  0.462   1.00 36.08  ? 163 ARG D N   1 
ATOM   8061  C  CA  . ARG D 1 163 ? 39.822  -1.468  0.153   1.00 34.29  ? 163 ARG D CA  1 
ATOM   8062  C  C   . ARG D 1 163 ? 40.764  -1.081  -0.985  1.00 33.42  ? 163 ARG D C   1 
ATOM   8063  O  O   . ARG D 1 163 ? 41.956  -1.239  -0.818  1.00 37.70  ? 163 ARG D O   1 
ATOM   8064  C  CB  . ARG D 1 163 ? 39.016  -2.753  -0.103  1.00 43.32  ? 163 ARG D CB  1 
ATOM   8065  C  CG  . ARG D 1 163 ? 38.352  -3.399  1.116   1.00 53.66  ? 163 ARG D CG  1 
ATOM   8066  C  CD  . ARG D 1 163 ? 37.656  -4.756  0.892   1.00 52.68  ? 163 ARG D CD  1 
ATOM   8067  N  NE  . ARG D 1 163 ? 38.671  -5.778  1.178   1.00 53.41  ? 163 ARG D NE  1 
ATOM   8068  N  N   . ARG D 1 164 ? 40.263  -0.477  -2.077  1.00 31.55  ? 164 ARG D N   1 
ATOM   8069  C  CA  . ARG D 1 164 ? 41.072  -0.115  -3.250  1.00 31.59  ? 164 ARG D CA  1 
ATOM   8070  C  C   . ARG D 1 164 ? 42.102  0.953   -2.857  1.00 32.71  ? 164 ARG D C   1 
ATOM   8071  O  O   . ARG D 1 164 ? 43.180  1.003   -3.423  1.00 35.14  ? 164 ARG D O   1 
ATOM   8072  C  CB  . ARG D 1 164 ? 40.232  0.234   -4.522  1.00 36.90  ? 164 ARG D CB  1 
ATOM   8073  C  CG  . ARG D 1 164 ? 40.652  1.082   -5.749  1.00 34.48  ? 164 ARG D CG  1 
ATOM   8074  N  N   . ALA D 1 165 ? 41.803  1.834   -1.901  1.00 30.69  ? 165 ALA D N   1 
ATOM   8075  C  CA  . ALA D 1 165 ? 42.692  2.949   -1.644  1.00 28.84  ? 165 ALA D CA  1 
ATOM   8076  C  C   . ALA D 1 165 ? 43.818  2.563   -0.698  1.00 29.23  ? 165 ALA D C   1 
ATOM   8077  O  O   . ALA D 1 165 ? 44.872  3.230   -0.722  1.00 30.80  ? 165 ALA D O   1 
ATOM   8078  C  CB  . ALA D 1 165 ? 41.910  4.111   -1.080  1.00 29.28  ? 165 ALA D CB  1 
ATOM   8079  N  N   . VAL D 1 166 ? 43.584  1.557   0.160   1.00 27.39  ? 166 VAL D N   1 
ATOM   8080  C  CA  . VAL D 1 166 ? 44.500  1.385   1.271   1.00 29.36  ? 166 VAL D CA  1 
ATOM   8081  C  C   . VAL D 1 166 ? 45.305  0.087   1.191   1.00 27.50  ? 166 VAL D C   1 
ATOM   8082  O  O   . VAL D 1 166 ? 46.394  0.048   1.732   1.00 25.79  ? 166 VAL D O   1 
ATOM   8083  C  CB  . VAL D 1 166 ? 43.870  1.564   2.658   1.00 30.09  ? 166 VAL D CB  1 
ATOM   8084  C  CG1 . VAL D 1 166 ? 42.860  2.710   2.676   1.00 27.64  ? 166 VAL D CG1 1 
ATOM   8085  C  CG2 . VAL D 1 166 ? 43.268  0.257   3.123   1.00 31.28  ? 166 VAL D CG2 1 
ATOM   8086  N  N   . LEU D 1 167 ? 44.812  -0.945  0.515   1.00 30.33  ? 167 LEU D N   1 
ATOM   8087  C  CA  . LEU D 1 167 ? 45.447  -2.257  0.549   1.00 30.84  ? 167 LEU D CA  1 
ATOM   8088  C  C   . LEU D 1 167 ? 46.297  -2.523  -0.686  1.00 32.73  ? 167 LEU D C   1 
ATOM   8089  O  O   . LEU D 1 167 ? 45.893  -2.293  -1.836  1.00 32.08  ? 167 LEU D O   1 
ATOM   8090  C  CB  . LEU D 1 167 ? 44.376  -3.335  0.685   1.00 34.63  ? 167 LEU D CB  1 
ATOM   8091  C  CG  . LEU D 1 167 ? 43.557  -3.269  1.968   1.00 37.87  ? 167 LEU D CG  1 
ATOM   8092  C  CD1 . LEU D 1 167 ? 42.469  -4.311  1.957   1.00 35.43  ? 167 LEU D CD1 1 
ATOM   8093  C  CD2 . LEU D 1 167 ? 44.516  -3.411  3.160   1.00 42.52  ? 167 LEU D CD2 1 
ATOM   8094  N  N   . VAL D 1 168 ? 47.502  -3.024  -0.410  1.00 32.43  ? 168 VAL D N   1 
ATOM   8095  C  CA  . VAL D 1 168 ? 48.415  -3.403  -1.463  1.00 33.56  ? 168 VAL D CA  1 
ATOM   8096  C  C   . VAL D 1 168 ? 47.769  -4.548  -2.242  1.00 32.65  ? 168 VAL D C   1 
ATOM   8097  O  O   . VAL D 1 168 ? 47.165  -5.438  -1.655  1.00 28.15  ? 168 VAL D O   1 
ATOM   8098  C  CB  . VAL D 1 168 ? 49.773  -3.772  -0.841  1.00 32.53  ? 168 VAL D CB  1 
ATOM   8099  C  CG1 . VAL D 1 168 ? 50.697  -4.430  -1.863  1.00 32.82  ? 168 VAL D CG1 1 
ATOM   8100  C  CG2 . VAL D 1 168 ? 50.452  -2.548  -0.213  1.00 31.23  ? 168 VAL D CG2 1 
ATOM   8101  N  N   . GLY D 1 169 ? 47.882  -4.508  -3.571  1.00 37.04  ? 169 GLY D N   1 
ATOM   8102  C  CA  . GLY D 1 169 ? 47.390  -5.613  -4.387  1.00 40.18  ? 169 GLY D CA  1 
ATOM   8103  C  C   . GLY D 1 169 ? 48.488  -6.219  -5.268  1.00 43.12  ? 169 GLY D C   1 
ATOM   8104  O  O   . GLY D 1 169 ? 49.626  -6.453  -4.825  1.00 42.20  ? 169 GLY D O   1 
ATOM   8105  N  N   . ALA D 1 170 ? 48.111  -6.451  -6.537  1.00 44.51  ? 170 ALA D N   1 
ATOM   8106  C  CA  . ALA D 1 170 ? 48.957  -7.119  -7.515  1.00 38.43  ? 170 ALA D CA  1 
ATOM   8107  C  C   . ALA D 1 170 ? 50.208  -6.305  -7.861  1.00 37.45  ? 170 ALA D C   1 
ATOM   8108  O  O   . ALA D 1 170 ? 51.166  -6.879  -8.337  1.00 38.34  ? 170 ALA D O   1 
ATOM   8109  C  CB  . ALA D 1 170 ? 48.153  -7.431  -8.743  1.00 34.60  ? 170 ALA D CB  1 
ATOM   8110  N  N   . GLU D 1 171 ? 50.254  -4.999  -7.592  1.00 33.32  ? 171 GLU D N   1 
ATOM   8111  C  CA  . GLU D 1 171 ? 51.432  -4.202  -7.912  1.00 34.51  ? 171 GLU D CA  1 
ATOM   8112  C  C   . GLU D 1 171 ? 52.629  -4.556  -7.020  1.00 39.23  ? 171 GLU D C   1 
ATOM   8113  O  O   . GLU D 1 171 ? 53.738  -4.112  -7.302  1.00 37.53  ? 171 GLU D O   1 
ATOM   8114  C  CB  . GLU D 1 171 ? 51.087  -2.707  -7.899  1.00 33.37  ? 171 GLU D CB  1 
ATOM   8115  C  CG  . GLU D 1 171 ? 51.004  -2.056  -6.529  1.00 36.42  ? 171 GLU D CG  1 
ATOM   8116  C  CD  . GLU D 1 171 ? 49.785  -2.356  -5.646  1.00 40.45  ? 171 GLU D CD  1 
ATOM   8117  O  OE1 . GLU D 1 171 ? 48.892  -3.124  -6.057  1.00 37.83  ? 171 GLU D OE1 1 
ATOM   8118  O  OE2 . GLU D 1 171 ? 49.708  -1.791  -4.503  1.00 39.18  ? 171 GLU D OE2 1 
ATOM   8119  N  N   . ASP D 1 172 ? 52.419  -5.320  -5.935  1.00 47.42  ? 172 ASP D N   1 
ATOM   8120  C  CA  . ASP D 1 172 ? 53.511  -5.804  -5.091  1.00 44.67  ? 172 ASP D CA  1 
ATOM   8121  C  C   . ASP D 1 172 ? 53.019  -7.078  -4.405  1.00 47.49  ? 172 ASP D C   1 
ATOM   8122  O  O   . ASP D 1 172 ? 52.787  -7.113  -3.193  1.00 44.14  ? 172 ASP D O   1 
ATOM   8123  C  CB  . ASP D 1 172 ? 53.994  -4.753  -4.099  1.00 42.43  ? 172 ASP D CB  1 
ATOM   8124  C  CG  . ASP D 1 172 ? 55.294  -5.072  -3.366  1.00 41.39  ? 172 ASP D CG  1 
ATOM   8125  O  OD1 . ASP D 1 172 ? 55.916  -6.100  -3.682  1.00 42.52  ? 172 ASP D OD1 1 
ATOM   8126  O  OD2 . ASP D 1 172 ? 55.665  -4.316  -2.454  1.00 39.96  ? 172 ASP D OD2 1 
ATOM   8127  N  N   . PRO D 1 173 ? 52.838  -8.160  -5.199  1.00 43.61  ? 173 PRO D N   1 
ATOM   8128  C  CA  . PRO D 1 173 ? 51.963  -9.283  -4.812  1.00 37.54  ? 173 PRO D CA  1 
ATOM   8129  C  C   . PRO D 1 173 ? 52.402  -10.085 -3.595  1.00 38.70  ? 173 PRO D C   1 
ATOM   8130  O  O   . PRO D 1 173 ? 51.593  -10.705 -2.918  1.00 40.53  ? 173 PRO D O   1 
ATOM   8131  C  CB  . PRO D 1 173 ? 51.920  -10.165 -6.035  1.00 37.04  ? 173 PRO D CB  1 
ATOM   8132  C  CG  . PRO D 1 173 ? 53.079  -9.696  -6.880  1.00 37.68  ? 173 PRO D CG  1 
ATOM   8133  C  CD  . PRO D 1 173 ? 53.488  -8.303  -6.508  1.00 35.68  ? 173 PRO D CD  1 
ATOM   8134  N  N   . ALA D 1 174 ? 53.704  -10.063 -3.323  1.00 39.38  ? 174 ALA D N   1 
ATOM   8135  C  CA  . ALA D 1 174 ? 54.250  -10.683 -2.135  1.00 37.52  ? 174 ALA D CA  1 
ATOM   8136  C  C   . ALA D 1 174 ? 53.643  -10.091 -0.859  1.00 38.87  ? 174 ALA D C   1 
ATOM   8137  O  O   . ALA D 1 174 ? 53.639  -10.756 0.172   1.00 37.33  ? 174 ALA D O   1 
ATOM   8138  C  CB  . ALA D 1 174 ? 55.753  -10.471 -2.150  1.00 39.21  ? 174 ALA D CB  1 
ATOM   8139  N  N   . PHE D 1 175 ? 53.215  -8.810  -0.907  1.00 37.85  ? 175 PHE D N   1 
ATOM   8140  C  CA  . PHE D 1 175 ? 52.830  -8.068  0.286   1.00 36.03  ? 175 PHE D CA  1 
ATOM   8141  C  C   . PHE D 1 175 ? 51.392  -7.550  0.202   1.00 38.50  ? 175 PHE D C   1 
ATOM   8142  O  O   . PHE D 1 175 ? 50.988  -6.709  0.992   1.00 33.90  ? 175 PHE D O   1 
ATOM   8143  C  CB  . PHE D 1 175 ? 53.818  -6.922  0.421   1.00 37.58  ? 175 PHE D CB  1 
ATOM   8144  C  CG  . PHE D 1 175 ? 55.226  -7.404  0.739   1.00 41.39  ? 175 PHE D CG  1 
ATOM   8145  C  CD1 . PHE D 1 175 ? 55.525  -7.978  1.973   1.00 35.81  ? 175 PHE D CD1 1 
ATOM   8146  C  CD2 . PHE D 1 175 ? 56.252  -7.225  -0.179  1.00 40.96  ? 175 PHE D CD2 1 
ATOM   8147  C  CE1 . PHE D 1 175 ? 56.807  -8.353  2.284   1.00 34.32  ? 175 PHE D CE1 1 
ATOM   8148  C  CE2 . PHE D 1 175 ? 57.534  -7.639  0.118   1.00 35.50  ? 175 PHE D CE2 1 
ATOM   8149  C  CZ  . PHE D 1 175 ? 57.811  -8.179  1.349   1.00 36.82  ? 175 PHE D CZ  1 
ATOM   8150  N  N   . ALA D 1 176 ? 50.616  -8.094  -0.742  1.00 35.81  ? 176 ALA D N   1 
ATOM   8151  C  CA  . ALA D 1 176 ? 49.178  -7.904  -0.808  1.00 34.07  ? 176 ALA D CA  1 
ATOM   8152  C  C   . ALA D 1 176 ? 48.550  -8.078  0.567   1.00 32.48  ? 176 ALA D C   1 
ATOM   8153  O  O   . ALA D 1 176 ? 48.838  -9.062  1.249   1.00 34.62  ? 176 ALA D O   1 
ATOM   8154  C  CB  . ALA D 1 176 ? 48.591  -8.891  -1.795  1.00 36.34  ? 176 ALA D CB  1 
ATOM   8155  N  N   . GLY D 1 177 ? 47.695  -7.105  0.934   1.00 32.40  ? 177 GLY D N   1 
ATOM   8156  C  CA  . GLY D 1 177 ? 46.977  -7.104  2.197   1.00 34.32  ? 177 GLY D CA  1 
ATOM   8157  C  C   . GLY D 1 177 ? 47.580  -6.116  3.199   1.00 31.62  ? 177 GLY D C   1 
ATOM   8158  O  O   . GLY D 1 177 ? 47.080  -5.860  4.325   1.00 34.46  ? 177 GLY D O   1 
ATOM   8159  N  N   . GLY D 1 178 ? 48.716  -5.588  2.763   1.00 31.35  ? 178 GLY D N   1 
ATOM   8160  C  CA  . GLY D 1 178 ? 49.441  -4.618  3.554   1.00 30.01  ? 178 GLY D CA  1 
ATOM   8161  C  C   . GLY D 1 178 ? 48.967  -3.214  3.214   1.00 26.99  ? 178 GLY D C   1 
ATOM   8162  O  O   . GLY D 1 178 ? 48.097  -3.028  2.350   1.00 22.69  ? 178 GLY D O   1 
ATOM   8163  N  N   . SER D 1 179 ? 49.542  -2.267  3.959   1.00 23.87  ? 179 SER D N   1 
ATOM   8164  C  CA  . SER D 1 179 ? 49.274  -0.875  3.751   1.00 22.09  ? 179 SER D CA  1 
ATOM   8165  C  C   . SER D 1 179 ? 50.437  -0.085  4.315   1.00 22.07  ? 179 SER D C   1 
ATOM   8166  O  O   . SER D 1 179 ? 51.331  -0.643  4.953   1.00 23.47  ? 179 SER D O   1 
ATOM   8167  C  CB  . SER D 1 179 ? 47.967  -0.511  4.396   1.00 24.85  ? 179 SER D CB  1 
ATOM   8168  O  OG  . SER D 1 179 ? 47.493  0.777   4.008   1.00 25.03  ? 179 SER D OG  1 
ATOM   8169  N  N   . TYR D 1 180 ? 50.404  1.217   4.037   1.00 21.39  ? 180 TYR D N   1 
ATOM   8170  C  CA  . TYR D 1 180 ? 51.448  2.127   4.441   1.00 21.45  ? 180 TYR D CA  1 
ATOM   8171  C  C   . TYR D 1 180 ? 50.801  3.171   5.325   1.00 22.00  ? 180 TYR D C   1 
ATOM   8172  O  O   . TYR D 1 180 ? 49.881  3.872   4.895   1.00 25.41  ? 180 TYR D O   1 
ATOM   8173  C  CB  . TYR D 1 180 ? 52.168  2.772   3.240   1.00 22.15  ? 180 TYR D CB  1 
ATOM   8174  C  CG  . TYR D 1 180 ? 52.957  1.804   2.376   1.00 21.93  ? 180 TYR D CG  1 
ATOM   8175  C  CD1 . TYR D 1 180 ? 52.358  1.087   1.340   1.00 23.00  ? 180 TYR D CD1 1 
ATOM   8176  C  CD2 . TYR D 1 180 ? 54.310  1.568   2.641   1.00 26.15  ? 180 TYR D CD2 1 
ATOM   8177  C  CE1 . TYR D 1 180 ? 53.079  0.168   0.586   1.00 22.98  ? 180 TYR D CE1 1 
ATOM   8178  C  CE2 . TYR D 1 180 ? 55.049  0.657   1.894   1.00 25.14  ? 180 TYR D CE2 1 
ATOM   8179  C  CZ  . TYR D 1 180 ? 54.425  -0.034  0.868   1.00 24.17  ? 180 TYR D CZ  1 
ATOM   8180  O  OH  . TYR D 1 180 ? 55.178  -0.886  0.140   1.00 25.39  ? 180 TYR D OH  1 
ATOM   8181  N  N   . ALA D 1 181 ? 51.388  3.331   6.516   1.00 19.95  ? 181 ALA D N   1 
ATOM   8182  C  CA  . ALA D 1 181 ? 50.908  4.287   7.475   1.00 20.47  ? 181 ALA D CA  1 
ATOM   8183  C  C   . ALA D 1 181 ? 51.919  5.405   7.647   1.00 21.04  ? 181 ALA D C   1 
ATOM   8184  O  O   . ALA D 1 181 ? 53.086  5.132   7.919   1.00 19.83  ? 181 ALA D O   1 
ATOM   8185  C  CB  . ALA D 1 181 ? 50.645  3.586   8.795   1.00 22.83  ? 181 ALA D CB  1 
ATOM   8186  N  N   . VAL D 1 182 ? 51.437  6.646   7.539   1.00 19.31  ? 182 VAL D N   1 
ATOM   8187  C  CA  . VAL D 1 182 ? 52.194  7.796   7.968   1.00 20.60  ? 182 VAL D CA  1 
ATOM   8188  C  C   . VAL D 1 182 ? 51.551  8.353   9.228   1.00 19.81  ? 182 VAL D C   1 
ATOM   8189  O  O   . VAL D 1 182 ? 50.321  8.508   9.271   1.00 21.86  ? 182 VAL D O   1 
ATOM   8190  C  CB  . VAL D 1 182 ? 52.174  8.851   6.842   1.00 25.52  ? 182 VAL D CB  1 
ATOM   8191  C  CG1 . VAL D 1 182 ? 52.759  10.198  7.286   1.00 24.81  ? 182 VAL D CG1 1 
ATOM   8192  C  CG2 . VAL D 1 182 ? 52.845  8.328   5.569   1.00 27.35  ? 182 VAL D CG2 1 
ATOM   8193  N  N   . VAL D 1 183 ? 52.401  8.696   10.212  1.00 18.02  ? 183 VAL D N   1 
ATOM   8194  C  CA  . VAL D 1 183 ? 51.969  9.309   11.446  1.00 17.77  ? 183 VAL D CA  1 
ATOM   8195  C  C   . VAL D 1 183 ? 52.675  10.645  11.583  1.00 18.25  ? 183 VAL D C   1 
ATOM   8196  O  O   . VAL D 1 183 ? 53.829  10.797  11.248  1.00 19.13  ? 183 VAL D O   1 
ATOM   8197  C  CB  . VAL D 1 183 ? 52.163  8.424   12.698  1.00 17.97  ? 183 VAL D CB  1 
ATOM   8198  C  CG1 . VAL D 1 183 ? 51.410  7.092   12.605  1.00 17.65  ? 183 VAL D CG1 1 
ATOM   8199  C  CG2 . VAL D 1 183 ? 53.614  8.141   12.974  1.00 17.84  ? 183 VAL D CG2 1 
ATOM   8200  N  N   . GLN D 1 184 ? 51.936  11.634  12.075  1.00 21.33  ? 184 GLN D N   1 
ATOM   8201  C  CA  . GLN D 1 184 ? 52.510  12.888  12.514  1.00 21.90  ? 184 GLN D CA  1 
ATOM   8202  C  C   . GLN D 1 184 ? 51.731  13.377  13.732  1.00 23.76  ? 184 GLN D C   1 
ATOM   8203  O  O   . GLN D 1 184 ? 50.504  13.436  13.721  1.00 24.21  ? 184 GLN D O   1 
ATOM   8204  C  CB  . GLN D 1 184 ? 52.343  13.972  11.448  1.00 23.65  ? 184 GLN D CB  1 
ATOM   8205  C  CG  . GLN D 1 184 ? 53.104  13.759  10.150  1.00 21.95  ? 184 GLN D CG  1 
ATOM   8206  C  CD  . GLN D 1 184 ? 52.942  14.986  9.287   1.00 21.88  ? 184 GLN D CD  1 
ATOM   8207  O  OE1 . GLN D 1 184 ? 51.853  15.198  8.764   1.00 18.67  ? 184 GLN D OE1 1 
ATOM   8208  N  NE2 . GLN D 1 184 ? 53.974  15.822  9.187   1.00 22.75  ? 184 GLN D NE2 1 
ATOM   8209  N  N   . LYS D 1 185 ? 52.454  13.775  14.779  1.00 21.18  ? 185 LYS D N   1 
ATOM   8210  C  CA  . LYS D 1 185 ? 51.796  14.387  15.908  1.00 20.06  ? 185 LYS D CA  1 
ATOM   8211  C  C   . LYS D 1 185 ? 51.819  15.886  15.695  1.00 19.94  ? 185 LYS D C   1 
ATOM   8212  O  O   . LYS D 1 185 ? 52.900  16.452  15.568  1.00 19.58  ? 185 LYS D O   1 
ATOM   8213  C  CB  . LYS D 1 185 ? 52.535  13.961  17.174  1.00 20.72  ? 185 LYS D CB  1 
ATOM   8214  C  CG  . LYS D 1 185 ? 52.037  14.688  18.359  1.00 24.16  ? 185 LYS D CG  1 
ATOM   8215  C  CD  . LYS D 1 185 ? 52.293  13.997  19.683  1.00 28.93  ? 185 LYS D CD  1 
ATOM   8216  C  CE  . LYS D 1 185 ? 53.698  14.038  20.060  1.00 27.29  ? 185 LYS D CE  1 
ATOM   8217  N  NZ  . LYS D 1 185 ? 53.835  13.323  21.317  1.00 26.01  ? 185 LYS D NZ  1 
ATOM   8218  N  N   . TYR D 1 186 ? 50.647  16.523  15.702  1.00 20.52  ? 186 TYR D N   1 
ATOM   8219  C  CA  . TYR D 1 186 ? 50.549  17.984  15.584  1.00 20.46  ? 186 TYR D CA  1 
ATOM   8220  C  C   . TYR D 1 186 ? 50.107  18.635  16.894  1.00 19.73  ? 186 TYR D C   1 
ATOM   8221  O  O   . TYR D 1 186 ? 49.251  18.116  17.577  1.00 18.88  ? 186 TYR D O   1 
ATOM   8222  C  CB  . TYR D 1 186 ? 49.527  18.418  14.521  1.00 19.94  ? 186 TYR D CB  1 
ATOM   8223  C  CG  . TYR D 1 186 ? 49.952  18.208  13.080  1.00 17.22  ? 186 TYR D CG  1 
ATOM   8224  C  CD1 . TYR D 1 186 ? 49.799  16.976  12.468  1.00 17.05  ? 186 TYR D CD1 1 
ATOM   8225  C  CD2 . TYR D 1 186 ? 50.476  19.254  12.356  1.00 16.04  ? 186 TYR D CD2 1 
ATOM   8226  C  CE1 . TYR D 1 186 ? 50.188  16.797  11.156  1.00 19.71  ? 186 TYR D CE1 1 
ATOM   8227  C  CE2 . TYR D 1 186 ? 50.826  19.096  11.030  1.00 18.81  ? 186 TYR D CE2 1 
ATOM   8228  C  CZ  . TYR D 1 186 ? 50.705  17.859  10.432  1.00 19.29  ? 186 TYR D CZ  1 
ATOM   8229  O  OH  . TYR D 1 186 ? 51.096  17.669  9.141   1.00 21.44  ? 186 TYR D OH  1 
ATOM   8230  N  N   . LEU D 1 187 ? 50.681  19.795  17.205  1.00 20.02  ? 187 LEU D N   1 
ATOM   8231  C  CA  . LEU D 1 187 ? 50.219  20.615  18.300  1.00 22.97  ? 187 LEU D CA  1 
ATOM   8232  C  C   . LEU D 1 187 ? 49.632  21.900  17.725  1.00 23.89  ? 187 LEU D C   1 
ATOM   8233  O  O   . LEU D 1 187 ? 50.146  22.418  16.766  1.00 26.30  ? 187 LEU D O   1 
ATOM   8234  C  CB  . LEU D 1 187 ? 51.401  20.897  19.230  1.00 26.98  ? 187 LEU D CB  1 
ATOM   8235  C  CG  . LEU D 1 187 ? 52.003  19.674  19.941  1.00 28.07  ? 187 LEU D CG  1 
ATOM   8236  C  CD1 . LEU D 1 187 ? 53.214  19.983  20.698  1.00 29.57  ? 187 LEU D CD1 1 
ATOM   8237  C  CD2 . LEU D 1 187 ? 51.026  19.104  20.909  1.00 28.45  ? 187 LEU D CD2 1 
ATOM   8238  N  N   . HIS D 1 188 ? 48.583  22.442  18.336  1.00 22.99  ? 188 HIS D N   1 
ATOM   8239  C  CA  . HIS D 1 188 ? 47.839  23.537  17.753  1.00 21.69  ? 188 HIS D CA  1 
ATOM   8240  C  C   . HIS D 1 188 ? 48.026  24.750  18.639  1.00 22.15  ? 188 HIS D C   1 
ATOM   8241  O  O   . HIS D 1 188 ? 48.134  24.613  19.839  1.00 19.07  ? 188 HIS D O   1 
ATOM   8242  C  CB  . HIS D 1 188 ? 46.320  23.264  17.675  1.00 20.99  ? 188 HIS D CB  1 
ATOM   8243  C  CG  . HIS D 1 188 ? 45.945  22.146  16.785  1.00 19.78  ? 188 HIS D CG  1 
ATOM   8244  N  ND1 . HIS D 1 188 ? 46.071  22.266  15.427  1.00 19.66  ? 188 HIS D ND1 1 
ATOM   8245  C  CD2 . HIS D 1 188 ? 45.532  20.881  17.015  1.00 19.80  ? 188 HIS D CD2 1 
ATOM   8246  C  CE1 . HIS D 1 188 ? 45.678  21.125  14.865  1.00 22.78  ? 188 HIS D CE1 1 
ATOM   8247  N  NE2 . HIS D 1 188 ? 45.352  20.254  15.815  1.00 19.26  ? 188 HIS D NE2 1 
ATOM   8248  N  N   . ASP D 1 189 ? 48.021  25.916  17.994  1.00 22.50  ? 189 ASP D N   1 
ATOM   8249  C  CA  . ASP D 1 189 ? 47.996  27.214  18.621  1.00 21.64  ? 189 ASP D CA  1 
ATOM   8250  C  C   . ASP D 1 189 ? 46.541  27.611  18.712  1.00 19.12  ? 189 ASP D C   1 
ATOM   8251  O  O   . ASP D 1 189 ? 46.026  28.284  17.850  1.00 17.12  ? 189 ASP D O   1 
ATOM   8252  C  CB  . ASP D 1 189 ? 48.827  28.200  17.822  1.00 23.17  ? 189 ASP D CB  1 
ATOM   8253  C  CG  . ASP D 1 189 ? 48.872  29.590  18.426  1.00 28.20  ? 189 ASP D CG  1 
ATOM   8254  O  OD1 . ASP D 1 189 ? 48.144  29.814  19.463  1.00 24.92  ? 189 ASP D OD1 1 
ATOM   8255  O  OD2 . ASP D 1 189 ? 49.639  30.404  17.837  1.00 34.37  ? 189 ASP D OD2 1 
ATOM   8256  N  N   . ILE D 1 190 ? 45.907  27.187  19.785  1.00 21.63  ? 190 ILE D N   1 
ATOM   8257  C  CA  . ILE D 1 190 ? 44.480  27.343  19.946  1.00 24.19  ? 190 ILE D CA  1 
ATOM   8258  C  C   . ILE D 1 190 ? 44.127  28.802  20.177  1.00 25.82  ? 190 ILE D C   1 
ATOM   8259  O  O   . ILE D 1 190 ? 43.040  29.220  19.748  1.00 31.92  ? 190 ILE D O   1 
ATOM   8260  C  CB  . ILE D 1 190 ? 43.925  26.457  21.070  1.00 26.59  ? 190 ILE D CB  1 
ATOM   8261  C  CG1 . ILE D 1 190 ? 43.951  24.977  20.688  1.00 29.11  ? 190 ILE D CG1 1 
ATOM   8262  C  CG2 . ILE D 1 190 ? 42.507  26.916  21.409  1.00 27.75  ? 190 ILE D CG2 1 
ATOM   8263  C  CD1 . ILE D 1 190 ? 43.006  24.652  19.526  1.00 26.95  ? 190 ILE D CD1 1 
ATOM   8264  N  N   . ASP D 1 191 ? 44.988  29.570  20.843  1.00 25.02  ? 191 ASP D N   1 
ATOM   8265  C  CA  . ASP D 1 191 ? 44.647  30.960  21.096  1.00 27.98  ? 191 ASP D CA  1 
ATOM   8266  C  C   . ASP D 1 191 ? 44.514  31.677  19.765  1.00 27.22  ? 191 ASP D C   1 
ATOM   8267  O  O   . ASP D 1 191 ? 43.563  32.416  19.555  1.00 29.40  ? 191 ASP D O   1 
ATOM   8268  C  CB  . ASP D 1 191 ? 45.678  31.732  21.897  1.00 35.60  ? 191 ASP D CB  1 
ATOM   8269  C  CG  . ASP D 1 191 ? 45.836  31.301  23.340  1.00 46.22  ? 191 ASP D CG  1 
ATOM   8270  O  OD1 . ASP D 1 191 ? 44.820  30.990  23.968  1.00 46.75  ? 191 ASP D OD1 1 
ATOM   8271  O  OD2 . ASP D 1 191 ? 46.981  31.280  23.819  1.00 65.91  ? 191 ASP D OD2 1 
ATOM   8272  N  N   . ALA D 1 192 ? 45.477  31.456  18.867  1.00 26.94  ? 192 ALA D N   1 
ATOM   8273  C  CA  . ALA D 1 192 ? 45.423  32.088  17.560  1.00 25.47  ? 192 ALA D CA  1 
ATOM   8274  C  C   . ALA D 1 192 ? 44.167  31.663  16.825  1.00 26.10  ? 192 ALA D C   1 
ATOM   8275  O  O   . ALA D 1 192 ? 43.518  32.471  16.189  1.00 29.15  ? 192 ALA D O   1 
ATOM   8276  C  CB  . ALA D 1 192 ? 46.646  31.719  16.763  1.00 26.20  ? 192 ALA D CB  1 
ATOM   8277  N  N   . TRP D 1 193 ? 43.882  30.361  16.862  1.00 28.21  ? 193 TRP D N   1 
ATOM   8278  C  CA  . TRP D 1 193 ? 42.771  29.783  16.122  1.00 27.99  ? 193 TRP D CA  1 
ATOM   8279  C  C   . TRP D 1 193 ? 41.443  30.395  16.557  1.00 28.62  ? 193 TRP D C   1 
ATOM   8280  O  O   . TRP D 1 193 ? 40.630  30.772  15.717  1.00 26.44  ? 193 TRP D O   1 
ATOM   8281  C  CB  . TRP D 1 193 ? 42.760  28.278  16.357  1.00 25.67  ? 193 TRP D CB  1 
ATOM   8282  C  CG  . TRP D 1 193 ? 41.656  27.561  15.639  1.00 25.30  ? 193 TRP D CG  1 
ATOM   8283  C  CD1 . TRP D 1 193 ? 40.605  26.902  16.206  1.00 26.16  ? 193 TRP D CD1 1 
ATOM   8284  C  CD2 . TRP D 1 193 ? 41.513  27.414  14.217  1.00 23.44  ? 193 TRP D CD2 1 
ATOM   8285  N  NE1 . TRP D 1 193 ? 39.831  26.335  15.233  1.00 24.37  ? 193 TRP D NE1 1 
ATOM   8286  C  CE2 . TRP D 1 193 ? 40.356  26.640  14.009  1.00 24.95  ? 193 TRP D CE2 1 
ATOM   8287  C  CE3 . TRP D 1 193 ? 42.242  27.861  13.120  1.00 24.17  ? 193 TRP D CE3 1 
ATOM   8288  C  CZ2 . TRP D 1 193 ? 39.921  26.289  12.740  1.00 25.09  ? 193 TRP D CZ2 1 
ATOM   8289  C  CZ3 . TRP D 1 193 ? 41.798  27.547  11.862  1.00 25.88  ? 193 TRP D CZ3 1 
ATOM   8290  C  CH2 . TRP D 1 193 ? 40.669  26.742  11.676  1.00 27.91  ? 193 TRP D CH2 1 
ATOM   8291  N  N   . GLU D 1 194 ? 41.273  30.528  17.872  1.00 30.01  ? 194 GLU D N   1 
ATOM   8292  C  CA  . GLU D 1 194 ? 40.050  31.026  18.463  1.00 34.67  ? 194 GLU D CA  1 
ATOM   8293  C  C   . GLU D 1 194 ? 39.911  32.519  18.186  1.00 33.69  ? 194 GLU D C   1 
ATOM   8294  O  O   . GLU D 1 194 ? 38.828  33.073  18.364  1.00 37.52  ? 194 GLU D O   1 
ATOM   8295  C  CB  . GLU D 1 194 ? 39.996  30.692  19.951  1.00 36.77  ? 194 GLU D CB  1 
ATOM   8296  C  CG  . GLU D 1 194 ? 38.673  30.042  20.340  1.00 52.72  ? 194 GLU D CG  1 
ATOM   8297  C  CD  . GLU D 1 194 ? 38.947  28.700  21.013  1.00 71.46  ? 194 GLU D CD  1 
ATOM   8298  O  OE1 . GLU D 1 194 ? 39.452  28.558  22.159  1.00 76.66  ? 194 GLU D OE1 1 
ATOM   8299  O  OE2 . GLU D 1 194 ? 38.656  27.731  20.299  1.00 91.92  ? 194 GLU D OE2 1 
ATOM   8300  N  N   . GLY D 1 195 ? 40.967  33.161  17.695  1.00 27.99  ? 195 GLY D N   1 
ATOM   8301  C  CA  . GLY D 1 195 ? 40.852  34.564  17.342  1.00 27.85  ? 195 GLY D CA  1 
ATOM   8302  C  C   . GLY D 1 195 ? 40.304  34.794  15.938  1.00 26.08  ? 195 GLY D C   1 
ATOM   8303  O  O   . GLY D 1 195 ? 40.108  35.916  15.552  1.00 28.62  ? 195 GLY D O   1 
ATOM   8304  N  N   . LEU D 1 196 ? 40.158  33.763  15.126  1.00 26.05  ? 196 LEU D N   1 
ATOM   8305  C  CA  . LEU D 1 196 ? 39.547  33.912  13.813  1.00 27.78  ? 196 LEU D CA  1 
ATOM   8306  C  C   . LEU D 1 196 ? 38.042  33.892  13.990  1.00 24.11  ? 196 LEU D C   1 
ATOM   8307  O  O   . LEU D 1 196 ? 37.554  33.224  14.869  1.00 26.00  ? 196 LEU D O   1 
ATOM   8308  C  CB  . LEU D 1 196 ? 39.967  32.776  12.882  1.00 28.27  ? 196 LEU D CB  1 
ATOM   8309  C  CG  . LEU D 1 196 ? 41.463  32.621  12.618  1.00 32.52  ? 196 LEU D CG  1 
ATOM   8310  C  CD1 . LEU D 1 196 ? 41.768  31.646  11.477  1.00 37.41  ? 196 LEU D CD1 1 
ATOM   8311  C  CD2 . LEU D 1 196 ? 42.026  33.948  12.344  1.00 31.59  ? 196 LEU D CD2 1 
ATOM   8312  N  N   . SER D 1 197 ? 37.300  34.586  13.141  1.00 23.11  ? 197 SER D N   1 
ATOM   8313  C  CA  . SER D 1 197 ? 35.875  34.362  13.048  1.00 22.69  ? 197 SER D CA  1 
ATOM   8314  C  C   . SER D 1 197 ? 35.613  32.959  12.520  1.00 22.63  ? 197 SER D C   1 
ATOM   8315  O  O   . SER D 1 197 ? 36.474  32.318  11.956  1.00 23.10  ? 197 SER D O   1 
ATOM   8316  C  CB  . SER D 1 197 ? 35.264  35.353  12.134  1.00 24.92  ? 197 SER D CB  1 
ATOM   8317  O  OG  . SER D 1 197 ? 35.724  35.150  10.812  1.00 27.84  ? 197 SER D OG  1 
ATOM   8318  N  N   . VAL D 1 198 ? 34.396  32.474  12.661  1.00 24.04  ? 198 VAL D N   1 
ATOM   8319  C  CA  . VAL D 1 198 ? 34.074  31.169  12.105  1.00 23.97  ? 198 VAL D CA  1 
ATOM   8320  C  C   . VAL D 1 198 ? 34.249  31.165  10.585  1.00 23.18  ? 198 VAL D C   1 
ATOM   8321  O  O   . VAL D 1 198 ? 34.723  30.178  10.053  1.00 23.00  ? 198 VAL D O   1 
ATOM   8322  C  CB  . VAL D 1 198 ? 32.668  30.738  12.531  1.00 24.09  ? 198 VAL D CB  1 
ATOM   8323  C  CG1 . VAL D 1 198 ? 32.149  29.568  11.702  1.00 23.41  ? 198 VAL D CG1 1 
ATOM   8324  C  CG2 . VAL D 1 198 ? 32.680  30.436  14.012  1.00 25.99  ? 198 VAL D CG2 1 
ATOM   8325  N  N   . GLU D 1 199 ? 33.902  32.262  9.910   1.00 23.36  ? 199 GLU D N   1 
ATOM   8326  C  CA  . GLU D 1 199 ? 33.958  32.332  8.453   1.00 26.77  ? 199 GLU D CA  1 
ATOM   8327  C  C   . GLU D 1 199 ? 35.421  32.190  8.025   1.00 27.26  ? 199 GLU D C   1 
ATOM   8328  O  O   . GLU D 1 199 ? 35.731  31.528  7.050   1.00 28.04  ? 199 GLU D O   1 
ATOM   8329  C  CB  . GLU D 1 199 ? 33.339  33.605  7.854   1.00 32.22  ? 199 GLU D CB  1 
ATOM   8330  C  CG  . GLU D 1 199 ? 31.881  33.881  8.235   1.00 47.05  ? 199 GLU D CG  1 
ATOM   8331  C  CD  . GLU D 1 199 ? 31.297  33.882  9.687   1.00 46.94  ? 199 GLU D CD  1 
ATOM   8332  O  OE1 . GLU D 1 199 ? 32.029  34.465  10.545  1.00 33.95  ? 199 GLU D OE1 1 
ATOM   8333  O  OE2 . GLU D 1 199 ? 30.114  33.378  9.967   1.00 36.61  ? 199 GLU D OE2 1 
ATOM   8334  N  N   . ALA D 1 200 ? 36.337  32.760  8.810   1.00 26.10  ? 200 ALA D N   1 
ATOM   8335  C  CA  . ALA D 1 200 ? 37.766  32.690  8.529   1.00 28.91  ? 200 ALA D CA  1 
ATOM   8336  C  C   . ALA D 1 200 ? 38.298  31.269  8.714   1.00 27.64  ? 200 ALA D C   1 
ATOM   8337  O  O   . ALA D 1 200 ? 39.167  30.815  7.980   1.00 27.98  ? 200 ALA D O   1 
ATOM   8338  C  CB  . ALA D 1 200 ? 38.521  33.683  9.416   1.00 26.40  ? 200 ALA D CB  1 
ATOM   8339  N  N   . GLN D 1 201 ? 37.801  30.587  9.736   1.00 26.77  ? 201 GLN D N   1 
ATOM   8340  C  CA  . GLN D 1 201 ? 38.230  29.234  10.007  1.00 23.92  ? 201 GLN D CA  1 
ATOM   8341  C  C   . GLN D 1 201 ? 37.745  28.335  8.874   1.00 23.08  ? 201 GLN D C   1 
ATOM   8342  O  O   . GLN D 1 201 ? 38.447  27.399  8.483   1.00 20.91  ? 201 GLN D O   1 
ATOM   8343  C  CB  . GLN D 1 201 ? 37.636  28.731  11.325  1.00 23.73  ? 201 GLN D CB  1 
ATOM   8344  C  CG  . GLN D 1 201 ? 38.120  29.451  12.579  1.00 20.67  ? 201 GLN D CG  1 
ATOM   8345  C  CD  . GLN D 1 201 ? 37.540  28.855  13.830  1.00 19.77  ? 201 GLN D CD  1 
ATOM   8346  O  OE1 . GLN D 1 201 ? 36.583  28.082  13.807  1.00 21.09  ? 201 GLN D OE1 1 
ATOM   8347  N  NE2 . GLN D 1 201 ? 38.139  29.176  14.948  1.00 19.57  ? 201 GLN D NE2 1 
ATOM   8348  N  N   . GLU D 1 202 ? 36.536  28.611  8.370   1.00 24.56  ? 202 GLU D N   1 
ATOM   8349  C  CA  . GLU D 1 202 ? 35.962  27.802  7.306   1.00 28.18  ? 202 GLU D CA  1 
ATOM   8350  C  C   . GLU D 1 202 ? 36.794  27.938  6.023   1.00 29.30  ? 202 GLU D C   1 
ATOM   8351  O  O   . GLU D 1 202 ? 36.865  26.993  5.224   1.00 28.04  ? 202 GLU D O   1 
ATOM   8352  C  CB  . GLU D 1 202 ? 34.507  28.222  7.080   1.00 31.43  ? 202 GLU D CB  1 
ATOM   8353  C  CG  . GLU D 1 202 ? 33.547  27.748  8.169   1.00 31.27  ? 202 GLU D CG  1 
ATOM   8354  C  CD  . GLU D 1 202 ? 32.144  28.322  8.070   1.00 30.77  ? 202 GLU D CD  1 
ATOM   8355  O  OE1 . GLU D 1 202 ? 31.968  29.363  7.406   1.00 28.60  ? 202 GLU D OE1 1 
ATOM   8356  O  OE2 . GLU D 1 202 ? 31.219  27.706  8.642   1.00 27.21  ? 202 GLU D OE2 1 
ATOM   8357  N  N   . ARG D 1 203 ? 37.404  29.128  5.844   1.00 26.39  ? 203 ARG D N   1 
ATOM   8358  C  CA  . ARG D 1 203 ? 38.239  29.407  4.694   1.00 26.02  ? 203 ARG D CA  1 
ATOM   8359  C  C   . ARG D 1 203 ? 39.564  28.681  4.830   1.00 24.84  ? 203 ARG D C   1 
ATOM   8360  O  O   . ARG D 1 203 ? 40.177  28.347  3.810   1.00 23.13  ? 203 ARG D O   1 
ATOM   8361  C  CB  . ARG D 1 203 ? 38.494  30.910  4.563   1.00 33.07  ? 203 ARG D CB  1 
ATOM   8362  C  CG  . ARG D 1 203 ? 37.413  31.635  3.771   1.00 48.73  ? 203 ARG D CG  1 
ATOM   8363  C  CD  . ARG D 1 203 ? 37.823  32.961  3.082   1.00 60.95  ? 203 ARG D CD  1 
ATOM   8364  N  NE  . ARG D 1 203 ? 37.034  34.033  3.702   1.00 83.64  ? 203 ARG D NE  1 
ATOM   8365  C  CZ  . ARG D 1 203 ? 37.217  34.581  4.919   1.00 96.41  ? 203 ARG D CZ  1 
ATOM   8366  N  NH1 . ARG D 1 203 ? 38.423  34.580  5.474   1.00 99.14  ? 203 ARG D NH1 1 
ATOM   8367  N  NH2 . ARG D 1 203 ? 36.216  35.215  5.537   1.00 89.21  ? 203 ARG D NH2 1 
ATOM   8368  N  N   . VAL D 1 204 ? 39.995  28.431  6.076   1.00 24.37  ? 204 VAL D N   1 
ATOM   8369  C  CA  . VAL D 1 204 ? 41.188  27.645  6.316   1.00 21.60  ? 204 VAL D CA  1 
ATOM   8370  C  C   . VAL D 1 204 ? 40.957  26.169  5.987   1.00 22.37  ? 204 VAL D C   1 
ATOM   8371  O  O   . VAL D 1 204 ? 41.814  25.524  5.366   1.00 20.59  ? 204 VAL D O   1 
ATOM   8372  C  CB  . VAL D 1 204 ? 41.682  27.819  7.758   1.00 21.18  ? 204 VAL D CB  1 
ATOM   8373  C  CG1 . VAL D 1 204 ? 42.791  26.820  8.077   1.00 19.74  ? 204 VAL D CG1 1 
ATOM   8374  C  CG2 . VAL D 1 204 ? 42.113  29.262  8.042   1.00 21.54  ? 204 VAL D CG2 1 
ATOM   8375  N  N   . ILE D 1 205 ? 39.824  25.619  6.420   1.00 20.58  ? 205 ILE D N   1 
ATOM   8376  C  CA  . ILE D 1 205 ? 39.608  24.198  6.270   1.00 21.41  ? 205 ILE D CA  1 
ATOM   8377  C  C   . ILE D 1 205 ? 39.049  23.903  4.871   1.00 21.46  ? 205 ILE D C   1 
ATOM   8378  O  O   . ILE D 1 205 ? 39.505  22.993  4.184   1.00 23.35  ? 205 ILE D O   1 
ATOM   8379  C  CB  . ILE D 1 205 ? 38.666  23.748  7.401   1.00 24.96  ? 205 ILE D CB  1 
ATOM   8380  C  CG1 . ILE D 1 205 ? 39.282  23.993  8.793   1.00 25.84  ? 205 ILE D CG1 1 
ATOM   8381  C  CG2 . ILE D 1 205 ? 38.241  22.284  7.230   1.00 26.94  ? 205 ILE D CG2 1 
ATOM   8382  C  CD1 . ILE D 1 205 ? 40.507  23.132  9.065   1.00 26.07  ? 205 ILE D CD1 1 
ATOM   8383  N  N   . GLY D 1 206 ? 38.031  24.668  4.451   1.00 22.16  ? 206 GLY D N   1 
ATOM   8384  C  CA  . GLY D 1 206 ? 37.362  24.467  3.173   1.00 19.89  ? 206 GLY D CA  1 
ATOM   8385  C  C   . GLY D 1 206 ? 35.980  23.832  3.316   1.00 20.15  ? 206 GLY D C   1 
ATOM   8386  O  O   . GLY D 1 206 ? 35.370  23.433  2.344   1.00 21.06  ? 206 GLY D O   1 
ATOM   8387  N  N   . ARG D 1 207 ? 35.465  23.743  4.532   1.00 21.82  ? 207 ARG D N   1 
ATOM   8388  C  CA  . ARG D 1 207 ? 34.119  23.265  4.776   1.00 21.82  ? 207 ARG D CA  1 
ATOM   8389  C  C   . ARG D 1 207 ? 33.463  24.143  5.827   1.00 22.96  ? 207 ARG D C   1 
ATOM   8390  O  O   . ARG D 1 207 ? 34.150  24.872  6.529   1.00 24.53  ? 207 ARG D O   1 
ATOM   8391  C  CB  . ARG D 1 207 ? 34.136  21.834  5.328   1.00 23.07  ? 207 ARG D CB  1 
ATOM   8392  C  CG  . ARG D 1 207 ? 34.952  20.855  4.501   1.00 23.46  ? 207 ARG D CG  1 
ATOM   8393  C  CD  . ARG D 1 207 ? 34.850  19.475  5.156   1.00 26.78  ? 207 ARG D CD  1 
ATOM   8394  N  NE  . ARG D 1 207 ? 33.569  18.776  4.954   1.00 29.26  ? 207 ARG D NE  1 
ATOM   8395  C  CZ  . ARG D 1 207 ? 33.110  18.083  3.875   1.00 28.21  ? 207 ARG D CZ  1 
ATOM   8396  N  NH1 . ARG D 1 207 ? 33.803  17.859  2.795   1.00 33.39  ? 207 ARG D NH1 1 
ATOM   8397  N  NH2 . ARG D 1 207 ? 31.906  17.585  3.849   1.00 27.82  ? 207 ARG D NH2 1 
ATOM   8398  N  N   . ARG D 1 208 ? 32.138  24.028  5.956   1.00 29.63  ? 208 ARG D N   1 
ATOM   8399  C  CA  . ARG D 1 208 ? 31.366  24.798  6.925   1.00 28.56  ? 208 ARG D CA  1 
ATOM   8400  C  C   . ARG D 1 208 ? 31.517  24.168  8.292   1.00 25.07  ? 208 ARG D C   1 
ATOM   8401  O  O   . ARG D 1 208 ? 31.457  22.955  8.422   1.00 27.06  ? 208 ARG D O   1 
ATOM   8402  C  CB  . ARG D 1 208 ? 29.855  24.791  6.660   1.00 30.80  ? 208 ARG D CB  1 
ATOM   8403  C  CG  . ARG D 1 208 ? 29.383  25.312  5.317   1.00 34.91  ? 208 ARG D CG  1 
ATOM   8404  C  CD  . ARG D 1 208 ? 29.890  26.697  5.004   1.00 46.03  ? 208 ARG D CD  1 
ATOM   8405  N  NE  . ARG D 1 208 ? 29.439  27.702  5.972   1.00 60.29  ? 208 ARG D NE  1 
ATOM   8406  C  CZ  . ARG D 1 208 ? 28.190  28.098  6.148   1.00 66.66  ? 208 ARG D CZ  1 
ATOM   8407  N  NH1 . ARG D 1 208 ? 27.286  27.818  5.232   1.00 73.49  ? 208 ARG D NH1 1 
ATOM   8408  N  NH2 . ARG D 1 208 ? 27.867  28.817  7.215   1.00 60.02  ? 208 ARG D NH2 1 
ATOM   8409  N  N   . LYS D 1 209 ? 31.646  24.999  9.325   1.00 23.46  ? 209 LYS D N   1 
ATOM   8410  C  CA  . LYS D 1 209 ? 31.969  24.475  10.634  1.00 26.03  ? 209 LYS D CA  1 
ATOM   8411  C  C   . LYS D 1 209 ? 30.825  23.652  11.235  1.00 29.17  ? 209 LYS D C   1 
ATOM   8412  O  O   . LYS D 1 209 ? 31.033  22.463  11.524  1.00 34.97  ? 209 LYS D O   1 
ATOM   8413  C  CB  . LYS D 1 209 ? 32.390  25.594  11.573  1.00 25.09  ? 209 LYS D CB  1 
ATOM   8414  C  CG  . LYS D 1 209 ? 33.012  25.078  12.826  1.00 23.36  ? 209 LYS D CG  1 
ATOM   8415  C  CD  . LYS D 1 209 ? 33.684  26.174  13.624  1.00 25.04  ? 209 LYS D CD  1 
ATOM   8416  C  CE  . LYS D 1 209 ? 34.586  25.518  14.633  1.00 28.85  ? 209 LYS D CE  1 
ATOM   8417  N  NZ  . LYS D 1 209 ? 35.093  26.491  15.597  1.00 30.61  ? 209 LYS D NZ  1 
ATOM   8418  N  N   . MET D 1 210 ? 29.645  24.273  11.402  1.00 30.05  ? 210 MET D N   1 
ATOM   8419  C  CA  . MET D 1 210 ? 28.542  23.615  12.093  1.00 34.93  ? 210 MET D CA  1 
ATOM   8420  C  C   . MET D 1 210 ? 27.955  22.478  11.241  1.00 32.65  ? 210 MET D C   1 
ATOM   8421  O  O   . MET D 1 210 ? 27.774  21.385  11.756  1.00 29.30  ? 210 MET D O   1 
ATOM   8422  C  CB  . MET D 1 210 ? 27.437  24.591  12.523  1.00 44.40  ? 210 MET D CB  1 
ATOM   8423  C  CG  . MET D 1 210 ? 26.578  24.029  13.665  1.00 55.56  ? 210 MET D CG  1 
ATOM   8424  S  SD  . MET D 1 210 ? 25.118  24.929  14.246  1.00 76.68  ? 210 MET D SD  1 
ATOM   8425  C  CE  . MET D 1 210 ? 24.095  25.315  12.805  1.00 67.78  ? 210 MET D CE  1 
ATOM   8426  N  N   . THR D 1 211 ? 27.703  22.692  9.936   1.00 28.47  ? 211 THR D N   1 
ATOM   8427  C  CA  . THR D 1 211 ? 26.940  21.753  9.127   1.00 28.23  ? 211 THR D CA  1 
ATOM   8428  C  C   . THR D 1 211 ? 27.847  20.782  8.367   1.00 29.40  ? 211 THR D C   1 
ATOM   8429  O  O   . THR D 1 211 ? 27.362  19.806  7.818   1.00 28.08  ? 211 THR D O   1 
ATOM   8430  C  CB  . THR D 1 211 ? 26.060  22.511  8.136   1.00 31.30  ? 211 THR D CB  1 
ATOM   8431  O  OG1 . THR D 1 211 ? 26.863  23.246  7.226   1.00 31.40  ? 211 THR D OG1 1 
ATOM   8432  C  CG2 . THR D 1 211 ? 25.301  23.655  8.765   1.00 32.71  ? 211 THR D CG2 1 
ATOM   8433  N  N   . ASP D 1 212 ? 29.159  21.051  8.304   1.00 32.03  ? 212 ASP D N   1 
ATOM   8434  C  CA  . ASP D 1 212 ? 30.116  20.172  7.635   1.00 30.89  ? 212 ASP D CA  1 
ATOM   8435  C  C   . ASP D 1 212 ? 29.839  20.040  6.145   1.00 28.73  ? 212 ASP D C   1 
ATOM   8436  O  O   . ASP D 1 212 ? 30.183  19.026  5.585   1.00 26.51  ? 212 ASP D O   1 
ATOM   8437  C  CB  . ASP D 1 212 ? 30.140  18.761  8.198   1.00 27.55  ? 212 ASP D CB  1 
ATOM   8438  C  CG  . ASP D 1 212 ? 31.386  17.926  7.928   1.00 28.37  ? 212 ASP D CG  1 
ATOM   8439  O  OD1 . ASP D 1 212 ? 32.518  18.511  7.661   1.00 31.49  ? 212 ASP D OD1 1 
ATOM   8440  O  OD2 . ASP D 1 212 ? 31.210  16.693  8.066   1.00 24.71  ? 212 ASP D OD2 1 
ATOM   8441  N  N   . VAL D 1 213 ? 29.249  21.054  5.511   1.00 30.17  ? 213 VAL D N   1 
ATOM   8442  C  CA  . VAL D 1 213 ? 29.067  21.038  4.065   1.00 32.57  ? 213 VAL D CA  1 
ATOM   8443  C  C   . VAL D 1 213 ? 30.279  21.674  3.381   1.00 31.24  ? 213 VAL D C   1 
ATOM   8444  O  O   . VAL D 1 213 ? 30.729  22.751  3.789   1.00 32.20  ? 213 VAL D O   1 
ATOM   8445  C  CB  . VAL D 1 213 ? 27.776  21.794  3.696   1.00 34.19  ? 213 VAL D CB  1 
ATOM   8446  C  CG1 . VAL D 1 213 ? 27.602  21.879  2.173   1.00 35.99  ? 213 VAL D CG1 1 
ATOM   8447  C  CG2 . VAL D 1 213 ? 26.548  21.157  4.345   1.00 35.56  ? 213 VAL D CG2 1 
ATOM   8448  N  N   . GLU D 1 214 ? 30.770  21.047  2.309   1.00 25.44  ? 214 GLU D N   1 
ATOM   8449  C  CA  . GLU D 1 214 ? 31.933  21.591  1.621   1.00 30.48  ? 214 GLU D CA  1 
ATOM   8450  C  C   . GLU D 1 214 ? 31.672  22.999  1.072   1.00 25.97  ? 214 GLU D C   1 
ATOM   8451  O  O   . GLU D 1 214 ? 30.584  23.258  0.618   1.00 23.69  ? 214 GLU D O   1 
ATOM   8452  C  CB  . GLU D 1 214 ? 32.258  20.602  0.517   1.00 33.42  ? 214 GLU D CB  1 
ATOM   8453  C  CG  . GLU D 1 214 ? 33.587  20.843  -0.187  1.00 33.81  ? 214 GLU D CG  1 
ATOM   8454  C  CD  . GLU D 1 214 ? 34.083  19.581  -0.872  1.00 34.65  ? 214 GLU D CD  1 
ATOM   8455  O  OE1 . GLU D 1 214 ? 33.518  18.421  -0.739  1.00 39.22  ? 214 GLU D OE1 1 
ATOM   8456  O  OE2 . GLU D 1 214 ? 35.101  19.812  -1.539  1.00 26.36  ? 214 GLU D OE2 1 
ATOM   8457  N  N   . LEU D 1 215 ? 32.646  23.902  1.129   1.00 26.57  ? 215 LEU D N   1 
ATOM   8458  C  CA  . LEU D 1 215 ? 32.509  25.186  0.468   1.00 29.82  ? 215 LEU D CA  1 
ATOM   8459  C  C   . LEU D 1 215 ? 32.490  24.931  -1.036  1.00 37.97  ? 215 LEU D C   1 
ATOM   8460  O  O   . LEU D 1 215 ? 33.262  24.076  -1.513  1.00 38.45  ? 215 LEU D O   1 
ATOM   8461  C  CB  . LEU D 1 215 ? 33.641  26.151  0.788   1.00 30.50  ? 215 LEU D CB  1 
ATOM   8462  C  CG  . LEU D 1 215 ? 33.804  26.589  2.244   1.00 36.29  ? 215 LEU D CG  1 
ATOM   8463  C  CD1 . LEU D 1 215 ? 34.834  27.711  2.383   1.00 36.52  ? 215 LEU D CD1 1 
ATOM   8464  C  CD2 . LEU D 1 215 ? 32.520  27.009  2.872   1.00 36.11  ? 215 LEU D CD2 1 
ATOM   8465  N  N   . SER D 1 216 ? 31.654  25.685  -1.789  1.00 42.31  ? 216 SER D N   1 
ATOM   8466  C  CA  . SER D 1 216 ? 31.574  25.480  -3.234  1.00 49.29  ? 216 SER D CA  1 
ATOM   8467  C  C   . SER D 1 216 ? 32.890  25.887  -3.905  1.00 54.43  ? 216 SER D C   1 
ATOM   8468  O  O   . SER D 1 216 ? 33.621  26.726  -3.354  1.00 49.98  ? 216 SER D O   1 
ATOM   8469  C  CB  . SER D 1 216 ? 30.407  26.192  -3.836  1.00 47.59  ? 216 SER D CB  1 
ATOM   8470  O  OG  . SER D 1 216 ? 30.572  27.587  -3.693  1.00 47.59  ? 216 SER D OG  1 
ATOM   8471  N  N   . ASP D 1 217 ? 33.171  25.280  -5.082  1.00 60.26  ? 217 ASP D N   1 
ATOM   8472  C  CA  . ASP D 1 217 ? 34.441  25.449  -5.777  1.00 59.88  ? 217 ASP D CA  1 
ATOM   8473  C  C   . ASP D 1 217 ? 34.695  26.914  -6.082  1.00 52.97  ? 217 ASP D C   1 
ATOM   8474  O  O   . ASP D 1 217 ? 35.846  27.337  -6.075  1.00 56.24  ? 217 ASP D O   1 
ATOM   8475  C  CB  . ASP D 1 217 ? 34.541  24.618  -7.041  1.00 60.49  ? 217 ASP D CB  1 
ATOM   8476  C  CG  . ASP D 1 217 ? 34.507  23.130  -6.751  1.00 73.98  ? 217 ASP D CG  1 
ATOM   8477  O  OD1 . ASP D 1 217 ? 35.319  22.672  -5.880  1.00 73.25  ? 217 ASP D OD1 1 
ATOM   8478  O  OD2 . ASP D 1 217 ? 33.644  22.457  -7.357  1.00 72.96  ? 217 ASP D OD2 1 
ATOM   8479  N  N   . ASP D 1 218 ? 33.624  27.679  -6.300  1.00 49.38  ? 218 ASP D N   1 
ATOM   8480  C  CA  . ASP D 1 218 ? 33.807  29.070  -6.674  1.00 57.82  ? 218 ASP D CA  1 
ATOM   8481  C  C   . ASP D 1 218 ? 34.203  29.903  -5.449  1.00 48.26  ? 218 ASP D C   1 
ATOM   8482  O  O   . ASP D 1 218 ? 34.625  31.036  -5.602  1.00 47.34  ? 218 ASP D O   1 
ATOM   8483  C  CB  . ASP D 1 218 ? 32.705  29.593  -7.596  1.00 61.99  ? 218 ASP D CB  1 
ATOM   8484  C  CG  . ASP D 1 218 ? 31.333  29.855  -6.994  1.00 73.41  ? 218 ASP D CG  1 
ATOM   8485  O  OD1 . ASP D 1 218 ? 31.163  29.710  -5.760  1.00 67.41  ? 218 ASP D OD1 1 
ATOM   8486  O  OD2 . ASP D 1 218 ? 30.443  30.228  -7.789  1.00 88.83  ? 218 ASP D OD2 1 
ATOM   8487  N  N   . VAL D 1 219 ? 34.142  29.376  -4.222  1.00 45.28  ? 219 VAL D N   1 
ATOM   8488  C  CA  . VAL D 1 219 ? 34.519  30.208  -3.077  1.00 48.21  ? 219 VAL D CA  1 
ATOM   8489  C  C   . VAL D 1 219 ? 35.611  29.569  -2.198  1.00 37.34  ? 219 VAL D C   1 
ATOM   8490  O  O   . VAL D 1 219 ? 36.219  30.220  -1.342  1.00 31.29  ? 219 VAL D O   1 
ATOM   8491  C  CB  . VAL D 1 219 ? 33.213  30.602  -2.332  1.00 53.55  ? 219 VAL D CB  1 
ATOM   8492  C  CG1 . VAL D 1 219 ? 33.235  30.362  -0.828  1.00 51.66  ? 219 VAL D CG1 1 
ATOM   8493  C  CG2 . VAL D 1 219 ? 32.773  32.031  -2.711  1.00 54.89  ? 219 VAL D CG2 1 
ATOM   8494  N  N   . LYS D 1 220 ? 35.908  28.304  -2.432  1.00 29.96  ? 220 LYS D N   1 
ATOM   8495  C  CA  . LYS D 1 220 ? 36.876  27.642  -1.581  1.00 34.16  ? 220 LYS D CA  1 
ATOM   8496  C  C   . LYS D 1 220 ? 38.280  28.137  -1.927  1.00 32.19  ? 220 LYS D C   1 
ATOM   8497  O  O   . LYS D 1 220 ? 38.726  27.980  -3.054  1.00 34.10  ? 220 LYS D O   1 
ATOM   8498  C  CB  . LYS D 1 220 ? 36.769  26.142  -1.849  1.00 35.34  ? 220 LYS D CB  1 
ATOM   8499  C  CG  . LYS D 1 220 ? 37.675  25.261  -0.999  1.00 34.24  ? 220 LYS D CG  1 
ATOM   8500  C  CD  . LYS D 1 220 ? 37.717  23.808  -1.467  1.00 33.87  ? 220 LYS D CD  1 
ATOM   8501  C  CE  . LYS D 1 220 ? 36.489  23.392  -2.174  1.00 35.62  ? 220 LYS D CE  1 
ATOM   8502  N  NZ  . LYS D 1 220 ? 36.278  21.963  -2.012  1.00 40.97  ? 220 LYS D NZ  1 
ATOM   8503  N  N   . PRO D 1 221 ? 39.031  28.757  -1.002  1.00 27.37  ? 221 PRO D N   1 
ATOM   8504  C  CA  . PRO D 1 221 ? 40.396  29.179  -1.309  1.00 26.43  ? 221 PRO D CA  1 
ATOM   8505  C  C   . PRO D 1 221 ? 41.313  28.029  -1.749  1.00 27.04  ? 221 PRO D C   1 
ATOM   8506  O  O   . PRO D 1 221 ? 41.138  26.884  -1.325  1.00 26.27  ? 221 PRO D O   1 
ATOM   8507  C  CB  . PRO D 1 221 ? 40.880  29.816  0.010   1.00 28.02  ? 221 PRO D CB  1 
ATOM   8508  C  CG  . PRO D 1 221 ? 39.641  30.135  0.789   1.00 27.63  ? 221 PRO D CG  1 
ATOM   8509  C  CD  . PRO D 1 221 ? 38.596  29.125  0.346   1.00 28.13  ? 221 PRO D CD  1 
ATOM   8510  N  N   . ALA D 1 222 ? 42.304  28.360  -2.594  1.00 22.85  ? 222 ALA D N   1 
ATOM   8511  C  CA  . ALA D 1 222 ? 43.287  27.412  -3.095  1.00 21.84  ? 222 ALA D CA  1 
ATOM   8512  C  C   . ALA D 1 222 ? 44.220  26.953  -1.995  1.00 21.73  ? 222 ALA D C   1 
ATOM   8513  O  O   . ALA D 1 222 ? 44.853  25.910  -2.155  1.00 22.57  ? 222 ALA D O   1 
ATOM   8514  C  CB  . ALA D 1 222 ? 44.140  28.023  -4.181  1.00 21.29  ? 222 ALA D CB  1 
ATOM   8515  N  N   . ASP D 1 223 ? 44.338  27.753  -0.915  1.00 19.20  ? 223 ASP D N   1 
ATOM   8516  C  CA  . ASP D 1 223 ? 45.245  27.406  0.159   1.00 21.94  ? 223 ASP D CA  1 
ATOM   8517  C  C   . ASP D 1 223 ? 44.477  26.816  1.344   1.00 20.73  ? 223 ASP D C   1 
ATOM   8518  O  O   . ASP D 1 223 ? 45.029  26.674  2.422   1.00 26.26  ? 223 ASP D O   1 
ATOM   8519  C  CB  . ASP D 1 223 ? 46.176  28.562  0.483   1.00 20.93  ? 223 ASP D CB  1 
ATOM   8520  C  CG  . ASP D 1 223 ? 45.492  29.787  1.068   1.00 24.03  ? 223 ASP D CG  1 
ATOM   8521  O  OD1 . ASP D 1 223 ? 44.257  29.886  0.944   1.00 25.41  ? 223 ASP D OD1 1 
ATOM   8522  O  OD2 . ASP D 1 223 ? 46.195  30.641  1.661   1.00 25.98  ? 223 ASP D OD2 1 
ATOM   8523  N  N   . SER D 1 224 ? 43.229  26.430  1.126   1.00 21.13  ? 224 SER D N   1 
ATOM   8524  C  CA  . SER D 1 224 ? 42.463  25.736  2.140   1.00 23.35  ? 224 SER D CA  1 
ATOM   8525  C  C   . SER D 1 224 ? 42.924  24.288  2.174   1.00 23.13  ? 224 SER D C   1 
ATOM   8526  O  O   . SER D 1 224 ? 43.468  23.778  1.201   1.00 25.52  ? 224 SER D O   1 
ATOM   8527  C  CB  . SER D 1 224 ? 40.965  25.833  1.878   1.00 27.34  ? 224 SER D CB  1 
ATOM   8528  O  OG  . SER D 1 224 ? 40.599  25.082  0.721   1.00 28.52  ? 224 SER D OG  1 
ATOM   8529  N  N   . HIS D 1 225 ? 42.690  23.646  3.315   1.00 23.78  ? 225 HIS D N   1 
ATOM   8530  C  CA  . HIS D 1 225 ? 43.206  22.315  3.601   1.00 23.70  ? 225 HIS D CA  1 
ATOM   8531  C  C   . HIS D 1 225 ? 42.589  21.305  2.652   1.00 21.86  ? 225 HIS D C   1 
ATOM   8532  O  O   . HIS D 1 225 ? 43.277  20.431  2.145   1.00 23.67  ? 225 HIS D O   1 
ATOM   8533  C  CB  . HIS D 1 225 ? 42.984  21.986  5.080   1.00 22.71  ? 225 HIS D CB  1 
ATOM   8534  C  CG  . HIS D 1 225 ? 43.349  20.615  5.475   1.00 20.44  ? 225 HIS D CG  1 
ATOM   8535  N  ND1 . HIS D 1 225 ? 44.649  20.192  5.387   1.00 23.69  ? 225 HIS D ND1 1 
ATOM   8536  C  CD2 . HIS D 1 225 ? 42.644  19.570  5.892   1.00 21.15  ? 225 HIS D CD2 1 
ATOM   8537  C  CE1 . HIS D 1 225 ? 44.708  18.922  5.745   1.00 21.74  ? 225 HIS D CE1 1 
ATOM   8538  N  NE2 . HIS D 1 225 ? 43.510  18.537  6.072   1.00 20.76  ? 225 HIS D NE2 1 
ATOM   8539  N  N   . VAL D 1 226 ? 41.291  21.439  2.405   1.00 25.11  ? 226 VAL D N   1 
ATOM   8540  C  CA  . VAL D 1 226 ? 40.581  20.497  1.545   1.00 27.31  ? 226 VAL D CA  1 
ATOM   8541  C  C   . VAL D 1 226 ? 41.002  20.688  0.083   1.00 24.09  ? 226 VAL D C   1 
ATOM   8542  O  O   . VAL D 1 226 ? 41.018  19.740  -0.703  1.00 23.88  ? 226 VAL D O   1 
ATOM   8543  C  CB  . VAL D 1 226 ? 39.060  20.623  1.759   1.00 29.83  ? 226 VAL D CB  1 
ATOM   8544  C  CG1 . VAL D 1 226 ? 38.295  20.102  0.562   1.00 33.51  ? 226 VAL D CG1 1 
ATOM   8545  C  CG2 . VAL D 1 226 ? 38.640  19.902  3.042   1.00 30.00  ? 226 VAL D CG2 1 
ATOM   8546  N  N   . ALA D 1 227 ? 41.307  21.927  -0.289  1.00 21.17  ? 227 ALA D N   1 
ATOM   8547  C  CA  . ALA D 1 227 ? 41.783  22.201  -1.627  1.00 22.45  ? 227 ALA D CA  1 
ATOM   8548  C  C   . ALA D 1 227 ? 43.131  21.518  -1.839  1.00 24.03  ? 227 ALA D C   1 
ATOM   8549  O  O   . ALA D 1 227 ? 43.277  20.800  -2.816  1.00 27.48  ? 227 ALA D O   1 
ATOM   8550  C  CB  . ALA D 1 227 ? 41.859  23.692  -1.861  1.00 23.32  ? 227 ALA D CB  1 
ATOM   8551  N  N   . LEU D 1 228 ? 44.102  21.701  -0.926  1.00 22.43  ? 228 LEU D N   1 
ATOM   8552  C  CA  . LEU D 1 228 ? 45.423  21.152  -1.154  1.00 22.97  ? 228 LEU D CA  1 
ATOM   8553  C  C   . LEU D 1 228 ? 45.513  19.641  -0.935  1.00 26.77  ? 228 LEU D C   1 
ATOM   8554  O  O   . LEU D 1 228 ? 46.471  19.053  -1.402  1.00 27.08  ? 228 LEU D O   1 
ATOM   8555  C  CB  . LEU D 1 228 ? 46.451  21.832  -0.285  1.00 24.52  ? 228 LEU D CB  1 
ATOM   8556  C  CG  . LEU D 1 228 ? 46.744  23.279  -0.650  1.00 27.42  ? 228 LEU D CG  1 
ATOM   8557  C  CD1 . LEU D 1 228 ? 47.459  23.978  0.532   1.00 29.41  ? 228 LEU D CD1 1 
ATOM   8558  C  CD2 . LEU D 1 228 ? 47.569  23.235  -1.918  1.00 27.18  ? 228 LEU D CD2 1 
ATOM   8559  N  N   . THR D 1 229 ? 44.580  18.995  -0.230  1.00 28.40  ? 229 THR D N   1 
ATOM   8560  C  CA  . THR D 1 229 ? 44.689  17.556  -0.010  1.00 26.74  ? 229 THR D CA  1 
ATOM   8561  C  C   . THR D 1 229 ? 43.762  16.802  -0.960  1.00 29.83  ? 229 THR D C   1 
ATOM   8562  O  O   . THR D 1 229 ? 43.622  15.589  -0.814  1.00 32.10  ? 229 THR D O   1 
ATOM   8563  C  CB  . THR D 1 229 ? 44.396  17.198  1.448   1.00 27.58  ? 229 THR D CB  1 
ATOM   8564  O  OG1 . THR D 1 229 ? 43.089  17.680  1.783   1.00 23.37  ? 229 THR D OG1 1 
ATOM   8565  C  CG2 . THR D 1 229 ? 45.447  17.750  2.394   1.00 26.00  ? 229 THR D CG2 1 
ATOM   8566  N  N   . SER D 1 230 ? 43.114  17.507  -1.911  1.00 31.43  ? 230 SER D N   1 
ATOM   8567  C  CA  . SER D 1 230 ? 42.440  16.870  -3.037  1.00 33.01  ? 230 SER D CA  1 
ATOM   8568  C  C   . SER D 1 230 ? 43.414  16.726  -4.195  1.00 33.05  ? 230 SER D C   1 
ATOM   8569  O  O   . SER D 1 230 ? 43.896  17.725  -4.677  1.00 32.88  ? 230 SER D O   1 
ATOM   8570  C  CB  . SER D 1 230 ? 41.245  17.626  -3.457  1.00 32.15  ? 230 SER D CB  1 
ATOM   8571  O  OG  . SER D 1 230 ? 40.284  17.603  -2.401  1.00 43.77  ? 230 SER D OG  1 
ATOM   8572  N  N   . VAL D 1 231 ? 43.741  15.495  -4.598  1.00 35.31  ? 231 VAL D N   1 
ATOM   8573  C  CA  . VAL D 1 231 ? 44.676  15.270  -5.682  1.00 37.69  ? 231 VAL D CA  1 
ATOM   8574  C  C   . VAL D 1 231 ? 44.037  14.259  -6.621  1.00 41.29  ? 231 VAL D C   1 
ATOM   8575  O  O   . VAL D 1 231 ? 43.380  13.336  -6.136  1.00 32.09  ? 231 VAL D O   1 
ATOM   8576  C  CB  . VAL D 1 231 ? 46.051  14.799  -5.172  1.00 43.03  ? 231 VAL D CB  1 
ATOM   8577  C  CG1 . VAL D 1 231 ? 46.398  15.479  -3.859  1.00 48.08  ? 231 VAL D CG1 1 
ATOM   8578  C  CG2 . VAL D 1 231 ? 46.191  13.297  -5.002  1.00 42.82  ? 231 VAL D CG2 1 
ATOM   8579  N  N   . THR D 1 232 ? 44.191  14.464  -7.940  1.00 51.05  ? 232 THR D N   1 
ATOM   8580  C  CA  . THR D 1 232 ? 43.604  13.535  -8.909  1.00 56.13  ? 232 THR D CA  1 
ATOM   8581  C  C   . THR D 1 232 ? 44.726  12.771  -9.614  1.00 49.77  ? 232 THR D C   1 
ATOM   8582  O  O   . THR D 1 232 ? 45.800  13.295  -9.839  1.00 51.09  ? 232 THR D O   1 
ATOM   8583  C  CB  . THR D 1 232 ? 42.664  14.235  -9.897  1.00 47.16  ? 232 THR D CB  1 
ATOM   8584  O  OG1 . THR D 1 232 ? 43.555  15.266  -10.318 1.00 42.71  ? 232 THR D OG1 1 
ATOM   8585  C  CG2 . THR D 1 232 ? 41.413  14.837  -9.271  1.00 39.76  ? 232 THR D CG2 1 
ATOM   8586  N  N   . GLY D 1 233 ? 44.475  11.493  -9.898  1.00 53.04  ? 233 GLY D N   1 
ATOM   8587  C  CA  . GLY D 1 233 ? 45.438  10.636  -10.563 1.00 58.01  ? 233 GLY D CA  1 
ATOM   8588  C  C   . GLY D 1 233 ? 45.381  10.859  -12.066 1.00 64.64  ? 233 GLY D C   1 
ATOM   8589  O  O   . GLY D 1 233 ? 44.573  11.658  -12.534 1.00 69.24  ? 233 GLY D O   1 
ATOM   8590  N  N   . PRO D 1 234 ? 46.280  10.206  -12.839 1.00 75.37  ? 234 PRO D N   1 
ATOM   8591  C  CA  . PRO D 1 234 ? 46.247  10.305  -14.307 1.00 74.95  ? 234 PRO D CA  1 
ATOM   8592  C  C   . PRO D 1 234 ? 44.864  10.237  -14.974 1.00 75.51  ? 234 PRO D C   1 
ATOM   8593  O  O   . PRO D 1 234 ? 44.543  11.076  -15.811 1.00 72.77  ? 234 PRO D O   1 
ATOM   8594  C  CB  . PRO D 1 234 ? 47.194  9.165   -14.742 1.00 70.66  ? 234 PRO D CB  1 
ATOM   8595  C  CG  . PRO D 1 234 ? 48.182  9.016   -13.578 1.00 72.24  ? 234 PRO D CG  1 
ATOM   8596  C  CD  . PRO D 1 234 ? 47.408  9.401   -12.322 1.00 71.35  ? 234 PRO D CD  1 
ATOM   8597  N  N   . ASP D 1 235 ? 44.004  9.304   -14.541 1.00 74.13  ? 235 ASP D N   1 
ATOM   8598  C  CA  . ASP D 1 235 ? 42.663  9.137   -15.092 1.00 70.89  ? 235 ASP D CA  1 
ATOM   8599  C  C   . ASP D 1 235 ? 41.733  10.315  -14.778 1.00 72.25  ? 235 ASP D C   1 
ATOM   8600  O  O   . ASP D 1 235 ? 40.630  10.380  -15.314 1.00 82.16  ? 235 ASP D O   1 
ATOM   8601  C  CB  . ASP D 1 235 ? 42.027  7.852   -14.575 1.00 63.15  ? 235 ASP D CB  1 
ATOM   8602  C  CG  . ASP D 1 235 ? 42.423  7.516   -13.147 1.00 68.75  ? 235 ASP D CG  1 
ATOM   8603  O  OD1 . ASP D 1 235 ? 42.835  8.428   -12.367 1.00 64.09  ? 235 ASP D OD1 1 
ATOM   8604  O  OD2 . ASP D 1 235 ? 42.390  6.325   -12.845 1.00 73.24  ? 235 ASP D OD2 1 
ATOM   8605  N  N   . GLY D 1 236 ? 42.110  11.219  -13.858 1.00 70.76  ? 236 GLY D N   1 
ATOM   8606  C  CA  . GLY D 1 236 ? 41.161  12.199  -13.346 1.00 62.05  ? 236 GLY D CA  1 
ATOM   8607  C  C   . GLY D 1 236 ? 40.325  11.678  -12.176 1.00 57.66  ? 236 GLY D C   1 
ATOM   8608  O  O   . GLY D 1 236 ? 39.479  12.416  -11.697 1.00 49.76  ? 236 GLY D O   1 
ATOM   8609  N  N   . SER D 1 237 ? 40.558  10.426  -11.731 1.00 66.04  ? 237 SER D N   1 
ATOM   8610  C  CA  . SER D 1 237 ? 40.011  9.903   -10.483 1.00 63.31  ? 237 SER D CA  1 
ATOM   8611  C  C   . SER D 1 237 ? 40.741  10.482  -9.280  1.00 66.13  ? 237 SER D C   1 
ATOM   8612  O  O   . SER D 1 237 ? 41.973  10.556  -9.303  1.00 55.85  ? 237 SER D O   1 
ATOM   8613  C  CB  . SER D 1 237 ? 40.142  8.419   -10.414 1.00 59.98  ? 237 SER D CB  1 
ATOM   8614  O  OG  . SER D 1 237 ? 39.367  7.834   -11.441 1.00 74.53  ? 237 SER D OG  1 
ATOM   8615  N  N   . ASP D 1 238 ? 39.982  10.797  -8.213  1.00 58.71  ? 238 ASP D N   1 
ATOM   8616  C  CA  . ASP D 1 238 ? 40.553  11.219  -6.947  1.00 54.40  ? 238 ASP D CA  1 
ATOM   8617  C  C   . ASP D 1 238 ? 41.480  10.154  -6.358  1.00 49.56  ? 238 ASP D C   1 
ATOM   8618  O  O   . ASP D 1 238 ? 41.179  8.965   -6.378  1.00 50.64  ? 238 ASP D O   1 
ATOM   8619  C  CB  . ASP D 1 238 ? 39.437  11.613  -5.998  1.00 58.50  ? 238 ASP D CB  1 
ATOM   8620  C  CG  . ASP D 1 238 ? 38.798  12.947  -6.375  1.00 68.07  ? 238 ASP D CG  1 
ATOM   8621  O  OD1 . ASP D 1 238 ? 39.562  13.921  -6.574  1.00 70.96  ? 238 ASP D OD1 1 
ATOM   8622  O  OD2 . ASP D 1 238 ? 37.549  13.024  -6.479  1.00 67.92  ? 238 ASP D OD2 1 
ATOM   8623  N  N   . LEU D 1 239 ? 42.622  10.599  -5.824  1.00 42.75  ? 239 LEU D N   1 
ATOM   8624  C  CA  . LEU D 1 239 ? 43.485  9.748   -5.018  1.00 38.11  ? 239 LEU D CA  1 
ATOM   8625  C  C   . LEU D 1 239 ? 43.121  9.903   -3.545  1.00 27.26  ? 239 LEU D C   1 
ATOM   8626  O  O   . LEU D 1 239 ? 43.138  10.995  -3.039  1.00 26.13  ? 239 LEU D O   1 
ATOM   8627  C  CB  . LEU D 1 239 ? 44.936  10.162  -5.253  1.00 43.02  ? 239 LEU D CB  1 
ATOM   8628  C  CG  . LEU D 1 239 ? 45.524  9.855   -6.638  1.00 44.21  ? 239 LEU D CG  1 
ATOM   8629  C  CD1 . LEU D 1 239 ? 47.000  10.168  -6.548  1.00 44.84  ? 239 LEU D CD1 1 
ATOM   8630  C  CD2 . LEU D 1 239 ? 45.293  8.427   -7.137  1.00 41.11  ? 239 LEU D CD2 1 
ATOM   8631  N  N   . GLU D 1 240 ? 42.833  8.807   -2.856  1.00 25.11  ? 240 GLU D N   1 
ATOM   8632  C  CA  . GLU D 1 240 ? 42.243  8.880   -1.532  1.00 25.87  ? 240 GLU D CA  1 
ATOM   8633  C  C   . GLU D 1 240 ? 43.145  8.194   -0.506  1.00 27.38  ? 240 GLU D C   1 
ATOM   8634  O  O   . GLU D 1 240 ? 43.909  7.299   -0.837  1.00 30.98  ? 240 GLU D O   1 
ATOM   8635  C  CB  . GLU D 1 240 ? 40.886  8.215   -1.543  1.00 28.98  ? 240 GLU D CB  1 
ATOM   8636  C  CG  . GLU D 1 240 ? 39.980  8.723   -2.648  1.00 38.72  ? 240 GLU D CG  1 
ATOM   8637  C  CD  . GLU D 1 240 ? 38.622  8.038   -2.573  1.00 46.15  ? 240 GLU D CD  1 
ATOM   8638  O  OE1 . GLU D 1 240 ? 38.418  6.824   -2.850  1.00 49.77  ? 240 GLU D OE1 1 
ATOM   8639  O  OE2 . GLU D 1 240 ? 37.736  8.786   -2.167  1.00 50.28  ? 240 GLU D OE2 1 
ATOM   8640  N  N   . ILE D 1 241 ? 43.073  8.654   0.747   1.00 24.95  ? 241 ILE D N   1 
ATOM   8641  C  CA  . ILE D 1 241 ? 43.671  7.947   1.861   1.00 23.46  ? 241 ILE D CA  1 
ATOM   8642  C  C   . ILE D 1 241 ? 42.601  7.683   2.916   1.00 24.46  ? 241 ILE D C   1 
ATOM   8643  O  O   . ILE D 1 241 ? 41.495  8.201   2.856   1.00 24.35  ? 241 ILE D O   1 
ATOM   8644  C  CB  . ILE D 1 241 ? 44.867  8.717   2.451   1.00 25.81  ? 241 ILE D CB  1 
ATOM   8645  C  CG1 . ILE D 1 241 ? 44.436  10.022  3.091   1.00 23.55  ? 241 ILE D CG1 1 
ATOM   8646  C  CG2 . ILE D 1 241 ? 45.960  8.938   1.391   1.00 28.31  ? 241 ILE D CG2 1 
ATOM   8647  C  CD1 . ILE D 1 241 ? 45.577  10.807  3.695   1.00 23.37  ? 241 ILE D CD1 1 
ATOM   8648  N  N   . LEU D 1 242 ? 42.947  6.856   3.903   1.00 23.72  ? 242 LEU D N   1 
ATOM   8649  C  CA  . LEU D 1 242 ? 42.062  6.651   5.008   1.00 21.80  ? 242 LEU D CA  1 
ATOM   8650  C  C   . LEU D 1 242 ? 42.706  7.243   6.241   1.00 23.32  ? 242 LEU D C   1 
ATOM   8651  O  O   . LEU D 1 242 ? 43.758  6.773   6.627   1.00 24.21  ? 242 LEU D O   1 
ATOM   8652  C  CB  . LEU D 1 242 ? 41.870  5.159   5.180   1.00 22.54  ? 242 LEU D CB  1 
ATOM   8653  C  CG  . LEU D 1 242 ? 40.888  4.770   6.281   1.00 23.26  ? 242 LEU D CG  1 
ATOM   8654  C  CD1 . LEU D 1 242 ? 39.515  5.212   5.832   1.00 26.31  ? 242 LEU D CD1 1 
ATOM   8655  C  CD2 . LEU D 1 242 ? 40.927  3.273   6.466   1.00 23.69  ? 242 LEU D CD2 1 
ATOM   8656  N  N   . ARG D 1 243 ? 42.020  8.178   6.889   1.00 23.48  ? 243 ARG D N   1 
ATOM   8657  C  CA  . ARG D 1 243 ? 42.536  8.880   8.048   1.00 23.30  ? 243 ARG D CA  1 
ATOM   8658  C  C   . ARG D 1 243 ? 41.774  8.481   9.298   1.00 20.85  ? 243 ARG D C   1 
ATOM   8659  O  O   . ARG D 1 243 ? 40.609  8.177   9.215   1.00 20.56  ? 243 ARG D O   1 
ATOM   8660  C  CB  . ARG D 1 243 ? 42.332  10.389  7.922   1.00 21.27  ? 243 ARG D CB  1 
ATOM   8661  C  CG  . ARG D 1 243 ? 43.197  10.981  6.821   1.00 25.49  ? 243 ARG D CG  1 
ATOM   8662  C  CD  . ARG D 1 243 ? 42.743  12.395  6.528   1.00 25.05  ? 243 ARG D CD  1 
ATOM   8663  N  NE  . ARG D 1 243 ? 41.463  12.316  5.813   1.00 26.44  ? 243 ARG D NE  1 
ATOM   8664  C  CZ  . ARG D 1 243 ? 40.353  12.916  6.207   1.00 26.48  ? 243 ARG D CZ  1 
ATOM   8665  N  NH1 . ARG D 1 243 ? 40.381  13.738  7.246   1.00 27.95  ? 243 ARG D NH1 1 
ATOM   8666  N  NH2 . ARG D 1 243 ? 39.235  12.730  5.523   1.00 27.71  ? 243 ARG D NH2 1 
ATOM   8667  N  N   . ASP D 1 244 ? 42.427  8.539   10.457  1.00 21.85  ? 244 ASP D N   1 
ATOM   8668  C  CA  . ASP D 1 244 ? 41.721  8.361   11.705  1.00 23.45  ? 244 ASP D CA  1 
ATOM   8669  C  C   . ASP D 1 244 ? 42.363  9.266   12.753  1.00 21.65  ? 244 ASP D C   1 
ATOM   8670  O  O   . ASP D 1 244 ? 42.797  8.812   13.788  1.00 22.96  ? 244 ASP D O   1 
ATOM   8671  C  CB  . ASP D 1 244 ? 41.645  6.886   12.051  1.00 25.46  ? 244 ASP D CB  1 
ATOM   8672  C  CG  . ASP D 1 244 ? 40.514  6.545   13.003  1.00 29.84  ? 244 ASP D CG  1 
ATOM   8673  O  OD1 . ASP D 1 244 ? 39.742  7.469   13.303  1.00 34.02  ? 244 ASP D OD1 1 
ATOM   8674  O  OD2 . ASP D 1 244 ? 40.452  5.386   13.463  1.00 25.76  ? 244 ASP D OD2 1 
ATOM   8675  N  N   . ASN D 1 245 ? 42.362  10.554  12.470  1.00 18.21  ? 245 ASN D N   1 
ATOM   8676  C  CA  . ASN D 1 245 ? 42.922  11.545  13.353  1.00 21.17  ? 245 ASN D CA  1 
ATOM   8677  C  C   . ASN D 1 245 ? 42.243  11.498  14.717  1.00 23.97  ? 245 ASN D C   1 
ATOM   8678  O  O   . ASN D 1 245 ? 41.019  11.388  14.814  1.00 27.29  ? 245 ASN D O   1 
ATOM   8679  C  CB  . ASN D 1 245 ? 42.717  12.951  12.787  1.00 22.52  ? 245 ASN D CB  1 
ATOM   8680  C  CG  . ASN D 1 245 ? 43.385  13.090  11.448  1.00 25.48  ? 245 ASN D CG  1 
ATOM   8681  O  OD1 . ASN D 1 245 ? 44.164  12.212  11.039  1.00 26.00  ? 245 ASN D OD1 1 
ATOM   8682  N  ND2 . ASN D 1 245 ? 43.078  14.172  10.755  1.00 26.99  ? 245 ASN D ND2 1 
ATOM   8683  N  N   . MET D 1 246 ? 43.052  11.662  15.764  1.00 22.69  ? 246 MET D N   1 
ATOM   8684  C  CA  . MET D 1 246 ? 42.575  11.652  17.128  1.00 23.95  ? 246 MET D CA  1 
ATOM   8685  C  C   . MET D 1 246 ? 43.117  12.855  17.878  1.00 23.28  ? 246 MET D C   1 
ATOM   8686  O  O   . MET D 1 246 ? 44.318  13.081  17.949  1.00 22.04  ? 246 MET D O   1 
ATOM   8687  C  CB  . MET D 1 246 ? 43.022  10.408  17.892  1.00 25.67  ? 246 MET D CB  1 
ATOM   8688  C  CG  . MET D 1 246 ? 42.430  9.131   17.341  1.00 27.21  ? 246 MET D CG  1 
ATOM   8689  S  SD  . MET D 1 246 ? 40.642  9.093   17.537  1.00 30.36  ? 246 MET D SD  1 
ATOM   8690  C  CE  . MET D 1 246 ? 40.589  8.714   19.299  1.00 29.96  ? 246 MET D CE  1 
ATOM   8691  N  N   . PRO D 1 247 ? 42.230  13.627  18.522  1.00 21.78  ? 247 PRO D N   1 
ATOM   8692  C  CA  . PRO D 1 247 ? 42.633  14.622  19.502  1.00 20.34  ? 247 PRO D CA  1 
ATOM   8693  C  C   . PRO D 1 247 ? 43.339  14.005  20.705  1.00 18.92  ? 247 PRO D C   1 
ATOM   8694  O  O   . PRO D 1 247 ? 43.081  12.875  21.093  1.00 18.07  ? 247 PRO D O   1 
ATOM   8695  C  CB  . PRO D 1 247 ? 41.332  15.246  19.956  1.00 20.71  ? 247 PRO D CB  1 
ATOM   8696  C  CG  . PRO D 1 247 ? 40.339  14.852  18.947  1.00 21.59  ? 247 PRO D CG  1 
ATOM   8697  C  CD  . PRO D 1 247 ? 40.787  13.530  18.379  1.00 22.17  ? 247 PRO D CD  1 
ATOM   8698  N  N   . PHE D 1 248 ? 44.205  14.807  21.304  1.00 17.89  ? 248 PHE D N   1 
ATOM   8699  C  CA  . PHE D 1 248 ? 44.846  14.448  22.543  1.00 20.16  ? 248 PHE D CA  1 
ATOM   8700  C  C   . PHE D 1 248 ? 45.248  15.748  23.202  1.00 21.47  ? 248 PHE D C   1 
ATOM   8701  O  O   . PHE D 1 248 ? 45.243  16.821  22.589  1.00 21.38  ? 248 PHE D O   1 
ATOM   8702  C  CB  . PHE D 1 248 ? 46.066  13.550  22.302  1.00 21.71  ? 248 PHE D CB  1 
ATOM   8703  C  CG  . PHE D 1 248 ? 47.220  14.271  21.619  1.00 22.02  ? 248 PHE D CG  1 
ATOM   8704  C  CD1 . PHE D 1 248 ? 47.308  14.337  20.236  1.00 20.84  ? 248 PHE D CD1 1 
ATOM   8705  C  CD2 . PHE D 1 248 ? 48.205  14.909  22.365  1.00 22.32  ? 248 PHE D CD2 1 
ATOM   8706  C  CE1 . PHE D 1 248 ? 48.341  15.017  19.609  1.00 20.42  ? 248 PHE D CE1 1 
ATOM   8707  C  CE2 . PHE D 1 248 ? 49.219  15.612  21.742  1.00 23.71  ? 248 PHE D CE2 1 
ATOM   8708  C  CZ  . PHE D 1 248 ? 49.284  15.664  20.357  1.00 22.19  ? 248 PHE D CZ  1 
ATOM   8709  N  N   . GLY D 1 249 ? 45.607  15.655  24.470  1.00 23.12  ? 249 GLY D N   1 
ATOM   8710  C  CA  . GLY D 1 249 ? 45.947  16.890  25.124  1.00 23.40  ? 249 GLY D CA  1 
ATOM   8711  C  C   . GLY D 1 249 ? 46.223  16.740  26.613  1.00 21.97  ? 249 GLY D C   1 
ATOM   8712  O  O   . GLY D 1 249 ? 46.013  15.706  27.242  1.00 18.88  ? 249 GLY D O   1 
ATOM   8713  N  N   . SER D 1 250 ? 46.702  17.859  27.117  1.00 22.71  ? 250 SER D N   1 
ATOM   8714  C  CA  . SER D 1 250 ? 46.949  18.055  28.515  1.00 27.71  ? 250 SER D CA  1 
ATOM   8715  C  C   . SER D 1 250 ? 46.594  19.506  28.842  1.00 26.92  ? 250 SER D C   1 
ATOM   8716  O  O   . SER D 1 250 ? 47.112  20.430  28.252  1.00 30.56  ? 250 SER D O   1 
ATOM   8717  C  CB  . SER D 1 250 ? 48.379  17.689  28.799  1.00 29.78  ? 250 SER D CB  1 
ATOM   8718  O  OG  . SER D 1 250 ? 48.805  18.425  29.938  1.00 37.88  ? 250 SER D OG  1 
ATOM   8719  N  N   . VAL D 1 251 ? 45.668  19.725  29.755  1.00 27.13  ? 251 VAL D N   1 
ATOM   8720  C  CA  . VAL D 1 251 ? 45.132  21.053  29.987  1.00 28.07  ? 251 VAL D CA  1 
ATOM   8721  C  C   . VAL D 1 251 ? 46.138  21.869  30.803  1.00 27.80  ? 251 VAL D C   1 
ATOM   8722  O  O   . VAL D 1 251 ? 46.334  23.064  30.565  1.00 26.94  ? 251 VAL D O   1 
ATOM   8723  C  CB  . VAL D 1 251 ? 43.768  20.781  30.671  1.00 32.82  ? 251 VAL D CB  1 
ATOM   8724  C  CG1 . VAL D 1 251 ? 43.478  21.746  31.788  1.00 36.09  ? 251 VAL D CG1 1 
ATOM   8725  C  CG2 . VAL D 1 251 ? 42.632  20.715  29.659  1.00 32.69  ? 251 VAL D CG2 1 
ATOM   8726  N  N   . GLY D 1 252 ? 46.824  21.188  31.730  1.00 30.06  ? 252 GLY D N   1 
ATOM   8727  C  CA  . GLY D 1 252 ? 47.792  21.829  32.614  1.00 34.14  ? 252 GLY D CA  1 
ATOM   8728  C  C   . GLY D 1 252 ? 49.004  22.352  31.855  1.00 34.59  ? 252 GLY D C   1 
ATOM   8729  O  O   . GLY D 1 252 ? 49.523  23.390  32.184  1.00 31.27  ? 252 GLY D O   1 
ATOM   8730  N  N   . ARG D 1 253 ? 49.425  21.649  30.806  1.00 41.11  ? 253 ARG D N   1 
ATOM   8731  C  CA  . ARG D 1 253 ? 50.574  22.068  30.024  1.00 42.98  ? 253 ARG D CA  1 
ATOM   8732  C  C   . ARG D 1 253 ? 50.159  22.844  28.769  1.00 40.48  ? 253 ARG D C   1 
ATOM   8733  O  O   . ARG D 1 253 ? 51.004  23.112  27.936  1.00 38.53  ? 253 ARG D O   1 
ATOM   8734  C  CB  . ARG D 1 253 ? 51.391  20.828  29.671  1.00 43.02  ? 253 ARG D CB  1 
ATOM   8735  C  CG  . ARG D 1 253 ? 51.885  20.132  30.932  1.00 51.01  ? 253 ARG D CG  1 
ATOM   8736  C  CD  . ARG D 1 253 ? 53.250  19.503  30.718  1.00 62.30  ? 253 ARG D CD  1 
ATOM   8737  N  NE  . ARG D 1 253 ? 53.191  18.816  29.422  1.00 74.01  ? 253 ARG D NE  1 
ATOM   8738  C  CZ  . ARG D 1 253 ? 52.397  17.778  29.136  1.00 79.05  ? 253 ARG D CZ  1 
ATOM   8739  N  NH1 . ARG D 1 253 ? 51.873  17.030  30.089  1.00 78.74  ? 253 ARG D NH1 1 
ATOM   8740  N  NH2 . ARG D 1 253 ? 52.178  17.441  27.882  1.00 86.01  ? 253 ARG D NH2 1 
ATOM   8741  N  N   . GLU D 1 254 ? 48.878  23.203  28.636  1.00 37.93  ? 254 GLU D N   1 
ATOM   8742  C  CA  . GLU D 1 254 ? 48.337  23.832  27.441  1.00 35.49  ? 254 GLU D CA  1 
ATOM   8743  C  C   . GLU D 1 254 ? 48.742  23.107  26.166  1.00 31.98  ? 254 GLU D C   1 
ATOM   8744  O  O   . GLU D 1 254 ? 49.132  23.739  25.205  1.00 40.67  ? 254 GLU D O   1 
ATOM   8745  C  CB  . GLU D 1 254 ? 48.801  25.282  27.348  1.00 41.04  ? 254 GLU D CB  1 
ATOM   8746  C  CG  . GLU D 1 254 ? 48.298  26.153  28.490  1.00 53.70  ? 254 GLU D CG  1 
ATOM   8747  C  CD  . GLU D 1 254 ? 48.817  27.578  28.424  1.00 57.03  ? 254 GLU D CD  1 
ATOM   8748  O  OE1 . GLU D 1 254 ? 49.057  28.153  27.325  1.00 54.24  ? 254 GLU D OE1 1 
ATOM   8749  O  OE2 . GLU D 1 254 ? 48.922  28.117  29.542  1.00 67.85  ? 254 GLU D OE2 1 
ATOM   8750  N  N   . GLU D 1 255 ? 48.647  21.777  26.135  1.00 36.01  ? 255 GLU D N   1 
ATOM   8751  C  CA  . GLU D 1 255 ? 48.818  20.999  24.909  1.00 35.71  ? 255 GLU D CA  1 
ATOM   8752  C  C   . GLU D 1 255 ? 47.472  20.588  24.328  1.00 30.87  ? 255 GLU D C   1 
ATOM   8753  O  O   . GLU D 1 255 ? 46.710  19.875  24.959  1.00 28.68  ? 255 GLU D O   1 
ATOM   8754  C  CB  . GLU D 1 255 ? 49.628  19.728  25.109  1.00 38.65  ? 255 GLU D CB  1 
ATOM   8755  C  CG  . GLU D 1 255 ? 51.084  20.050  25.404  1.00 49.41  ? 255 GLU D CG  1 
ATOM   8756  C  CD  . GLU D 1 255 ? 51.998  18.868  25.228  1.00 51.24  ? 255 GLU D CD  1 
ATOM   8757  O  OE1 . GLU D 1 255 ? 51.537  17.743  24.880  1.00 51.70  ? 255 GLU D OE1 1 
ATOM   8758  O  OE2 . GLU D 1 255 ? 53.195  19.151  25.415  1.00 50.58  ? 255 GLU D OE2 1 
ATOM   8759  N  N   . PHE D 1 256 ? 47.184  21.061  23.119  1.00 27.70  ? 256 PHE D N   1 
ATOM   8760  C  CA  . PHE D 1 256 ? 46.005  20.649  22.386  1.00 29.44  ? 256 PHE D CA  1 
ATOM   8761  C  C   . PHE D 1 256 ? 46.482  20.138  21.036  1.00 26.58  ? 256 PHE D C   1 
ATOM   8762  O  O   . PHE D 1 256 ? 47.141  20.880  20.334  1.00 26.30  ? 256 PHE D O   1 
ATOM   8763  C  CB  . PHE D 1 256 ? 45.064  21.855  22.258  1.00 32.97  ? 256 PHE D CB  1 
ATOM   8764  C  CG  . PHE D 1 256 ? 44.710  22.449  23.609  1.00 33.76  ? 256 PHE D CG  1 
ATOM   8765  C  CD1 . PHE D 1 256 ? 43.733  21.853  24.405  1.00 33.42  ? 256 PHE D CD1 1 
ATOM   8766  C  CD2 . PHE D 1 256 ? 45.363  23.582  24.089  1.00 33.35  ? 256 PHE D CD2 1 
ATOM   8767  C  CE1 . PHE D 1 256 ? 43.442  22.362  25.658  1.00 31.84  ? 256 PHE D CE1 1 
ATOM   8768  C  CE2 . PHE D 1 256 ? 45.045  24.087  25.336  1.00 31.09  ? 256 PHE D CE2 1 
ATOM   8769  C  CZ  . PHE D 1 256 ? 44.089  23.481  26.114  1.00 28.94  ? 256 PHE D CZ  1 
ATOM   8770  N  N   . GLY D 1 257 ? 46.177  18.884  20.697  1.00 23.20  ? 257 GLY D N   1 
ATOM   8771  C  CA  . GLY D 1 257 ? 46.884  18.249  19.595  1.00 25.77  ? 257 GLY D CA  1 
ATOM   8772  C  C   . GLY D 1 257 ? 45.950  17.447  18.700  1.00 22.14  ? 257 GLY D C   1 
ATOM   8773  O  O   . GLY D 1 257 ? 44.838  17.129  19.102  1.00 25.76  ? 257 GLY D O   1 
ATOM   8774  N  N   . THR D 1 258 ? 46.397  17.173  17.476  1.00 20.75  ? 258 THR D N   1 
ATOM   8775  C  CA  . THR D 1 258 ? 45.751  16.226  16.604  1.00 22.47  ? 258 THR D CA  1 
ATOM   8776  C  C   . THR D 1 258 ? 46.818  15.213  16.245  1.00 21.05  ? 258 THR D C   1 
ATOM   8777  O  O   . THR D 1 258 ? 47.875  15.606  15.786  1.00 22.03  ? 258 THR D O   1 
ATOM   8778  C  CB  . THR D 1 258 ? 45.132  16.909  15.375  1.00 25.50  ? 258 THR D CB  1 
ATOM   8779  O  OG1 . THR D 1 258 ? 43.989  17.685  15.787  1.00 31.88  ? 258 THR D OG1 1 
ATOM   8780  C  CG2 . THR D 1 258 ? 44.726  15.850  14.354  1.00 25.30  ? 258 THR D CG2 1 
ATOM   8781  N  N   . TYR D 1 259 ? 46.575  13.931  16.511  1.00 18.40  ? 259 TYR D N   1 
ATOM   8782  C  CA  . TYR D 1 259 ? 47.484  12.893  16.066  1.00 19.61  ? 259 TYR D CA  1 
ATOM   8783  C  C   . TYR D 1 259 ? 46.977  12.419  14.701  1.00 20.51  ? 259 TYR D C   1 
ATOM   8784  O  O   . TYR D 1 259 ? 45.919  11.819  14.596  1.00 21.12  ? 259 TYR D O   1 
ATOM   8785  C  CB  . TYR D 1 259 ? 47.632  11.751  17.083  1.00 20.28  ? 259 TYR D CB  1 
ATOM   8786  C  CG  . TYR D 1 259 ? 48.876  10.894  16.913  1.00 22.61  ? 259 TYR D CG  1 
ATOM   8787  C  CD1 . TYR D 1 259 ? 48.901  9.848   15.999  1.00 24.31  ? 259 TYR D CD1 1 
ATOM   8788  C  CD2 . TYR D 1 259 ? 50.014  11.105  17.670  1.00 25.62  ? 259 TYR D CD2 1 
ATOM   8789  C  CE1 . TYR D 1 259 ? 50.022  9.063   15.816  1.00 22.61  ? 259 TYR D CE1 1 
ATOM   8790  C  CE2 . TYR D 1 259 ? 51.137  10.313  17.517  1.00 28.08  ? 259 TYR D CE2 1 
ATOM   8791  C  CZ  . TYR D 1 259 ? 51.144  9.300   16.575  1.00 26.59  ? 259 TYR D CZ  1 
ATOM   8792  O  OH  . TYR D 1 259 ? 52.243  8.514   16.409  1.00 32.46  ? 259 TYR D OH  1 
ATOM   8793  N  N   . PHE D 1 260 ? 47.738  12.718  13.650  1.00 20.07  ? 260 PHE D N   1 
ATOM   8794  C  CA  . PHE D 1 260 ? 47.404  12.328  12.307  1.00 20.87  ? 260 PHE D CA  1 
ATOM   8795  C  C   . PHE D 1 260 ? 47.892  10.917  12.030  1.00 19.74  ? 260 PHE D C   1 
ATOM   8796  O  O   . PHE D 1 260 ? 49.073  10.634  12.222  1.00 18.72  ? 260 PHE D O   1 
ATOM   8797  C  CB  . PHE D 1 260 ? 48.080  13.292  11.338  1.00 22.12  ? 260 PHE D CB  1 
ATOM   8798  C  CG  . PHE D 1 260 ? 47.940  12.810  9.910   1.00 23.43  ? 260 PHE D CG  1 
ATOM   8799  C  CD1 . PHE D 1 260 ? 46.755  13.026  9.216   1.00 26.01  ? 260 PHE D CD1 1 
ATOM   8800  C  CD2 . PHE D 1 260 ? 48.956  12.104  9.294   1.00 23.83  ? 260 PHE D CD2 1 
ATOM   8801  C  CE1 . PHE D 1 260 ? 46.596  12.565  7.909   1.00 25.66  ? 260 PHE D CE1 1 
ATOM   8802  C  CE2 . PHE D 1 260 ? 48.781  11.616  8.012   1.00 26.50  ? 260 PHE D CE2 1 
ATOM   8803  C  CZ  . PHE D 1 260 ? 47.606  11.855  7.316   1.00 25.81  ? 260 PHE D CZ  1 
ATOM   8804  N  N   . ILE D 1 261 ? 46.996  10.078  11.499  1.00 19.12  ? 261 ILE D N   1 
ATOM   8805  C  CA  . ILE D 1 261 ? 47.408  8.814   10.918  1.00 18.38  ? 261 ILE D CA  1 
ATOM   8806  C  C   . ILE D 1 261 ? 46.643  8.619   9.622   1.00 17.34  ? 261 ILE D C   1 
ATOM   8807  O  O   . ILE D 1 261 ? 45.462  8.798   9.557   1.00 16.25  ? 261 ILE D O   1 
ATOM   8808  C  CB  . ILE D 1 261 ? 47.261  7.610   11.879  1.00 20.96  ? 261 ILE D CB  1 
ATOM   8809  C  CG1 . ILE D 1 261 ? 47.855  6.357   11.290  1.00 24.09  ? 261 ILE D CG1 1 
ATOM   8810  C  CG2 . ILE D 1 261 ? 45.812  7.338   12.273  1.00 21.78  ? 261 ILE D CG2 1 
ATOM   8811  C  CD1 . ILE D 1 261 ? 48.090  5.244   12.289  1.00 26.67  ? 261 ILE D CD1 1 
ATOM   8812  N  N   . GLY D 1 262 ? 47.387  8.349   8.562   1.00 19.59  ? 262 GLY D N   1 
ATOM   8813  C  CA  . GLY D 1 262 ? 46.835  8.129   7.261   1.00 18.99  ? 262 GLY D CA  1 
ATOM   8814  C  C   . GLY D 1 262 ? 47.421  6.884   6.641   1.00 19.31  ? 262 GLY D C   1 
ATOM   8815  O  O   . GLY D 1 262 ? 48.645  6.717   6.514   1.00 26.75  ? 262 GLY D O   1 
ATOM   8816  N  N   . TYR D 1 263 ? 46.496  6.035   6.205   1.00 20.75  ? 263 TYR D N   1 
ATOM   8817  C  CA  . TYR D 1 263 ? 46.829  4.818   5.482   1.00 22.02  ? 263 TYR D CA  1 
ATOM   8818  C  C   . TYR D 1 263 ? 46.525  4.941   3.984   1.00 23.48  ? 263 TYR D C   1 
ATOM   8819  O  O   . TYR D 1 263 ? 45.512  5.520   3.581   1.00 18.61  ? 263 TYR D O   1 
ATOM   8820  C  CB  . TYR D 1 263 ? 45.984  3.695   6.051   1.00 22.87  ? 263 TYR D CB  1 
ATOM   8821  C  CG  . TYR D 1 263 ? 46.283  3.263   7.475   1.00 21.25  ? 263 TYR D CG  1 
ATOM   8822  C  CD1 . TYR D 1 263 ? 47.193  2.259   7.735   1.00 23.34  ? 263 TYR D CD1 1 
ATOM   8823  C  CD2 . TYR D 1 263 ? 45.540  3.767   8.533   1.00 20.53  ? 263 TYR D CD2 1 
ATOM   8824  C  CE1 . TYR D 1 263 ? 47.410  1.796   9.021   1.00 24.52  ? 263 TYR D CE1 1 
ATOM   8825  C  CE2 . TYR D 1 263 ? 45.755  3.323   9.826   1.00 22.80  ? 263 TYR D CE2 1 
ATOM   8826  C  CZ  . TYR D 1 263 ? 46.694  2.328   10.074  1.00 25.18  ? 263 TYR D CZ  1 
ATOM   8827  O  OH  . TYR D 1 263 ? 46.931  1.886   11.353  1.00 25.82  ? 263 TYR D OH  1 
ATOM   8828  N  N   . ALA D 1 264 ? 47.405  4.334   3.175   1.00 24.14  ? 264 ALA D N   1 
ATOM   8829  C  CA  . ALA D 1 264 ? 47.298  4.315   1.725   1.00 24.20  ? 264 ALA D CA  1 
ATOM   8830  C  C   . ALA D 1 264 ? 48.019  3.079   1.180   1.00 27.68  ? 264 ALA D C   1 
ATOM   8831  O  O   . ALA D 1 264 ? 48.951  2.603   1.821   1.00 26.64  ? 264 ALA D O   1 
ATOM   8832  C  CB  . ALA D 1 264 ? 47.919  5.562   1.187   1.00 22.79  ? 264 ALA D CB  1 
ATOM   8833  N  N   . ARG D 1 265 ? 47.631  2.608   -0.022  1.00 28.29  ? 265 ARG D N   1 
ATOM   8834  C  CA  . ARG D 1 265 ? 48.224  1.431   -0.656  1.00 28.67  ? 265 ARG D CA  1 
ATOM   8835  C  C   . ARG D 1 265 ? 49.658  1.702   -1.111  1.00 27.59  ? 265 ARG D C   1 
ATOM   8836  O  O   . ARG D 1 265 ? 50.418  0.769   -1.331  1.00 31.03  ? 265 ARG D O   1 
ATOM   8837  C  CB  . ARG D 1 265 ? 47.392  0.870   -1.827  1.00 32.66  ? 265 ARG D CB  1 
ATOM   8838  C  CG  . ARG D 1 265 ? 47.461  1.692   -3.096  1.00 41.28  ? 265 ARG D CG  1 
ATOM   8839  C  CD  . ARG D 1 265 ? 46.521  1.272   -4.238  1.00 46.99  ? 265 ARG D CD  1 
ATOM   8840  N  NE  . ARG D 1 265 ? 46.835  -0.110  -4.610  1.00 50.59  ? 265 ARG D NE  1 
ATOM   8841  C  CZ  . ARG D 1 265 ? 46.008  -1.095  -4.972  1.00 51.67  ? 265 ARG D CZ  1 
ATOM   8842  N  NH1 . ARG D 1 265 ? 44.704  -0.933  -5.035  1.00 47.53  ? 265 ARG D NH1 1 
ATOM   8843  N  NH2 . ARG D 1 265 ? 46.486  -2.283  -5.281  1.00 55.89  ? 265 ARG D NH2 1 
ATOM   8844  N  N   . THR D 1 266 ? 50.016  2.975   -1.285  1.00 26.92  ? 266 THR D N   1 
ATOM   8845  C  CA  . THR D 1 266 ? 51.369  3.396   -1.615  1.00 30.02  ? 266 THR D CA  1 
ATOM   8846  C  C   . THR D 1 266 ? 51.623  4.718   -0.902  1.00 31.36  ? 266 THR D C   1 
ATOM   8847  O  O   . THR D 1 266 ? 50.762  5.603   -0.863  1.00 33.27  ? 266 THR D O   1 
ATOM   8848  C  CB  . THR D 1 266 ? 51.600  3.557   -3.133  1.00 28.08  ? 266 THR D CB  1 
ATOM   8849  O  OG1 . THR D 1 266 ? 52.831  4.269   -3.298  1.00 33.91  ? 266 THR D OG1 1 
ATOM   8850  C  CG2 . THR D 1 266 ? 50.502  4.338   -3.833  1.00 25.63  ? 266 THR D CG2 1 
ATOM   8851  N  N   . PRO D 1 267 ? 52.835  4.943   -0.356  1.00 27.52  ? 267 PRO D N   1 
ATOM   8852  C  CA  . PRO D 1 267 ? 53.096  6.223   0.282   1.00 26.02  ? 267 PRO D CA  1 
ATOM   8853  C  C   . PRO D 1 267 ? 53.135  7.397   -0.691  1.00 28.52  ? 267 PRO D C   1 
ATOM   8854  O  O   . PRO D 1 267 ? 53.069  8.530   -0.224  1.00 26.90  ? 267 PRO D O   1 
ATOM   8855  C  CB  . PRO D 1 267 ? 54.408  5.998   1.008   1.00 27.07  ? 267 PRO D CB  1 
ATOM   8856  C  CG  . PRO D 1 267 ? 55.049  4.847   0.275   1.00 27.63  ? 267 PRO D CG  1 
ATOM   8857  C  CD  . PRO D 1 267 ? 53.952  4.002   -0.307  1.00 26.57  ? 267 PRO D CD  1 
ATOM   8858  N  N   . GLU D 1 268 ? 53.217  7.131   -2.015  1.00 29.72  ? 268 GLU D N   1 
ATOM   8859  C  CA  . GLU D 1 268 ? 53.365  8.206   -2.997  1.00 30.00  ? 268 GLU D CA  1 
ATOM   8860  C  C   . GLU D 1 268 ? 52.180  9.180   -2.824  1.00 27.13  ? 268 GLU D C   1 
ATOM   8861  O  O   . GLU D 1 268 ? 52.302  10.408  -2.894  1.00 24.61  ? 268 GLU D O   1 
ATOM   8862  C  CB  . GLU D 1 268 ? 53.657  7.676   -4.427  1.00 32.36  ? 268 GLU D CB  1 
ATOM   8863  C  CG  . GLU D 1 268 ? 54.944  6.862   -4.694  1.00 31.10  ? 268 GLU D CG  1 
ATOM   8864  N  N   . VAL D 1 269 ? 50.991  8.648   -2.542  1.00 27.32  ? 269 VAL D N   1 
ATOM   8865  C  CA  . VAL D 1 269 ? 49.788  9.479   -2.453  1.00 26.07  ? 269 VAL D CA  1 
ATOM   8866  C  C   . VAL D 1 269 ? 49.880  10.397  -1.241  1.00 24.32  ? 269 VAL D C   1 
ATOM   8867  O  O   . VAL D 1 269 ? 49.666  11.595  -1.360  1.00 20.32  ? 269 VAL D O   1 
ATOM   8868  C  CB  . VAL D 1 269 ? 48.554  8.557   -2.359  1.00 27.91  ? 269 VAL D CB  1 
ATOM   8869  C  CG1 . VAL D 1 269 ? 47.255  9.305   -2.083  1.00 27.62  ? 269 VAL D CG1 1 
ATOM   8870  C  CG2 . VAL D 1 269 ? 48.442  7.669   -3.603  1.00 27.84  ? 269 VAL D CG2 1 
ATOM   8871  N  N   . THR D 1 270 ? 50.162  9.794   -0.075  1.00 25.68  ? 270 THR D N   1 
ATOM   8872  C  CA  . THR D 1 270 ? 50.272  10.520  1.183   1.00 26.67  ? 270 THR D CA  1 
ATOM   8873  C  C   . THR D 1 270 ? 51.374  11.580  1.059   1.00 24.03  ? 270 THR D C   1 
ATOM   8874  O  O   . THR D 1 270 ? 51.204  12.702  1.516   1.00 20.71  ? 270 THR D O   1 
ATOM   8875  C  CB  . THR D 1 270 ? 50.530  9.560   2.351   1.00 26.14  ? 270 THR D CB  1 
ATOM   8876  O  OG1 . THR D 1 270 ? 49.608  8.464   2.379   1.00 25.88  ? 270 THR D OG1 1 
ATOM   8877  C  CG2 . THR D 1 270 ? 50.447  10.275  3.687   1.00 24.35  ? 270 THR D CG2 1 
ATOM   8878  N  N   . GLU D 1 271 ? 52.498  11.218  0.418   1.00 25.76  ? 271 GLU D N   1 
ATOM   8879  C  CA  . GLU D 1 271 ? 53.646  12.102  0.288   1.00 24.60  ? 271 GLU D CA  1 
ATOM   8880  C  C   . GLU D 1 271 ? 53.337  13.276  -0.646  1.00 22.29  ? 271 GLU D C   1 
ATOM   8881  O  O   . GLU D 1 271 ? 53.832  14.377  -0.451  1.00 20.70  ? 271 GLU D O   1 
ATOM   8882  C  CB  . GLU D 1 271 ? 54.893  11.331  -0.149  1.00 23.47  ? 271 GLU D CB  1 
ATOM   8883  C  CG  . GLU D 1 271 ? 55.575  10.632  1.015   1.00 26.41  ? 271 GLU D CG  1 
ATOM   8884  C  CD  . GLU D 1 271 ? 56.545  9.551   0.599   1.00 29.00  ? 271 GLU D CD  1 
ATOM   8885  O  OE1 . GLU D 1 271 ? 56.689  9.284   -0.615  1.00 29.24  ? 271 GLU D OE1 1 
ATOM   8886  O  OE2 . GLU D 1 271 ? 57.115  8.960   1.522   1.00 28.17  ? 271 GLU D OE2 1 
ATOM   8887  N  N   . THR D 1 272 ? 52.522  13.048  -1.659  1.00 21.84  ? 272 THR D N   1 
ATOM   8888  C  CA  . THR D 1 272 ? 52.122  14.140  -2.535  1.00 24.76  ? 272 THR D CA  1 
ATOM   8889  C  C   . THR D 1 272 ? 51.356  15.193  -1.736  1.00 26.32  ? 272 THR D C   1 
ATOM   8890  O  O   . THR D 1 272 ? 51.601  16.403  -1.877  1.00 25.31  ? 272 THR D O   1 
ATOM   8891  C  CB  . THR D 1 272 ? 51.236  13.602  -3.655  1.00 25.76  ? 272 THR D CB  1 
ATOM   8892  O  OG1 . THR D 1 272 ? 52.053  12.716  -4.382  1.00 23.79  ? 272 THR D OG1 1 
ATOM   8893  C  CG2 . THR D 1 272 ? 50.725  14.688  -4.580  1.00 26.54  ? 272 THR D CG2 1 
ATOM   8894  N  N   . MET D 1 273 ? 50.387  14.707  -0.942  1.00 22.88  ? 273 MET D N   1 
ATOM   8895  C  CA  . MET D 1 273 ? 49.539  15.603  -0.194  1.00 22.85  ? 273 MET D CA  1 
ATOM   8896  C  C   . MET D 1 273 ? 50.419  16.411  0.763   1.00 22.21  ? 273 MET D C   1 
ATOM   8897  O  O   . MET D 1 273 ? 50.248  17.622  0.935   1.00 20.20  ? 273 MET D O   1 
ATOM   8898  C  CB  . MET D 1 273 ? 48.473  14.802  0.559   1.00 23.77  ? 273 MET D CB  1 
ATOM   8899  C  CG  . MET D 1 273 ? 47.425  14.111  -0.302  1.00 22.62  ? 273 MET D CG  1 
ATOM   8900  S  SD  . MET D 1 273 ? 46.366  13.031  0.684   1.00 25.09  ? 273 MET D SD  1 
ATOM   8901  C  CE  . MET D 1 273 ? 45.193  12.382  -0.498  1.00 23.79  ? 273 MET D CE  1 
ATOM   8902  N  N   . LEU D 1 274 ? 51.399  15.738  1.359   1.00 20.15  ? 274 LEU D N   1 
ATOM   8903  C  CA  . LEU D 1 274 ? 52.310  16.409  2.275   1.00 21.63  ? 274 LEU D CA  1 
ATOM   8904  C  C   . LEU D 1 274 ? 53.139  17.496  1.586   1.00 20.32  ? 274 LEU D C   1 
ATOM   8905  O  O   . LEU D 1 274 ? 53.324  18.557  2.177   1.00 19.51  ? 274 LEU D O   1 
ATOM   8906  C  CB  . LEU D 1 274 ? 53.215  15.382  2.942   1.00 23.45  ? 274 LEU D CB  1 
ATOM   8907  C  CG  . LEU D 1 274 ? 52.612  14.651  4.161   1.00 23.63  ? 274 LEU D CG  1 
ATOM   8908  C  CD1 . LEU D 1 274 ? 53.387  13.463  4.670   1.00 22.30  ? 274 LEU D CD1 1 
ATOM   8909  C  CD2 . LEU D 1 274 ? 52.503  15.632  5.303   1.00 22.92  ? 274 LEU D CD2 1 
ATOM   8910  N  N   . GLU D 1 275 ? 53.622  17.233  0.367   1.00 21.40  ? 275 GLU D N   1 
ATOM   8911  C  CA  . GLU D 1 275 ? 54.404  18.214  -0.374  1.00 24.86  ? 275 GLU D CA  1 
ATOM   8912  C  C   . GLU D 1 275 ? 53.558  19.447  -0.670  1.00 23.32  ? 275 GLU D C   1 
ATOM   8913  O  O   . GLU D 1 275 ? 54.013  20.593  -0.499  1.00 25.22  ? 275 GLU D O   1 
ATOM   8914  C  CB  . GLU D 1 275 ? 54.942  17.713  -1.722  1.00 30.93  ? 275 GLU D CB  1 
ATOM   8915  C  CG  . GLU D 1 275 ? 56.131  16.768  -1.585  1.00 37.05  ? 275 GLU D CG  1 
ATOM   8916  C  CD  . GLU D 1 275 ? 56.483  15.922  -2.803  1.00 40.29  ? 275 GLU D CD  1 
ATOM   8917  O  OE1 . GLU D 1 275 ? 55.695  15.908  -3.755  1.00 41.46  ? 275 GLU D OE1 1 
ATOM   8918  O  OE2 . GLU D 1 275 ? 57.505  15.204  -2.740  1.00 44.16  ? 275 GLU D OE2 1 
ATOM   8919  N  N   . ARG D 1 276 ? 52.319  19.203  -1.099  1.00 22.62  ? 276 ARG D N   1 
ATOM   8920  C  CA  . ARG D 1 276 ? 51.421  20.306  -1.387  1.00 24.04  ? 276 ARG D CA  1 
ATOM   8921  C  C   . ARG D 1 276 ? 51.190  21.153  -0.150  1.00 25.33  ? 276 ARG D C   1 
ATOM   8922  O  O   . ARG D 1 276 ? 51.111  22.380  -0.271  1.00 23.26  ? 276 ARG D O   1 
ATOM   8923  C  CB  . ARG D 1 276 ? 50.084  19.798  -1.942  1.00 26.71  ? 276 ARG D CB  1 
ATOM   8924  C  CG  . ARG D 1 276 ? 50.329  19.399  -3.384  1.00 33.62  ? 276 ARG D CG  1 
ATOM   8925  C  CD  . ARG D 1 276 ? 49.509  18.270  -3.889  1.00 36.56  ? 276 ARG D CD  1 
ATOM   8926  N  NE  . ARG D 1 276 ? 48.110  18.676  -3.932  1.00 39.45  ? 276 ARG D NE  1 
ATOM   8927  C  CZ  . ARG D 1 276 ? 47.575  19.412  -4.866  1.00 41.61  ? 276 ARG D CZ  1 
ATOM   8928  N  NH1 . ARG D 1 276 ? 48.190  19.488  -6.016  1.00 47.13  ? 276 ARG D NH1 1 
ATOM   8929  N  NH2 . ARG D 1 276 ? 46.383  19.967  -4.698  1.00 39.17  ? 276 ARG D NH2 1 
ATOM   8930  N  N   . MET D 1 277 ? 51.042  20.490  1.021   1.00 23.49  ? 277 MET D N   1 
ATOM   8931  C  CA  . MET D 1 277 ? 50.714  21.212  2.235   1.00 22.87  ? 277 MET D CA  1 
ATOM   8932  C  C   . MET D 1 277 ? 51.926  22.017  2.700   1.00 22.41  ? 277 MET D C   1 
ATOM   8933  O  O   . MET D 1 277 ? 51.776  23.169  3.113   1.00 22.85  ? 277 MET D O   1 
ATOM   8934  C  CB  . MET D 1 277 ? 50.289  20.274  3.376   1.00 23.36  ? 277 MET D CB  1 
ATOM   8935  C  CG  . MET D 1 277 ? 48.942  19.607  3.239   1.00 22.48  ? 277 MET D CG  1 
ATOM   8936  S  SD  . MET D 1 277 ? 48.751  18.284  4.450   1.00 22.71  ? 277 MET D SD  1 
ATOM   8937  C  CE  . MET D 1 277 ? 48.695  19.275  5.946   1.00 22.85  ? 277 MET D CE  1 
ATOM   8938  N  N   . PHE D 1 278 ? 53.108  21.407  2.674   1.00 22.16  ? 278 PHE D N   1 
ATOM   8939  C  CA  . PHE D 1 278 ? 54.261  22.003  3.335   1.00 24.19  ? 278 PHE D CA  1 
ATOM   8940  C  C   . PHE D 1 278 ? 55.066  22.905  2.404   1.00 23.95  ? 278 PHE D C   1 
ATOM   8941  O  O   . PHE D 1 278 ? 55.641  23.924  2.855   1.00 22.60  ? 278 PHE D O   1 
ATOM   8942  C  CB  . PHE D 1 278 ? 55.139  20.875  3.910   1.00 25.77  ? 278 PHE D CB  1 
ATOM   8943  C  CG  . PHE D 1 278 ? 54.662  20.452  5.290   1.00 24.74  ? 278 PHE D CG  1 
ATOM   8944  C  CD1 . PHE D 1 278 ? 53.699  19.474  5.434   1.00 26.20  ? 278 PHE D CD1 1 
ATOM   8945  C  CD2 . PHE D 1 278 ? 55.105  21.115  6.421   1.00 24.53  ? 278 PHE D CD2 1 
ATOM   8946  C  CE1 . PHE D 1 278 ? 53.227  19.118  6.689   1.00 27.36  ? 278 PHE D CE1 1 
ATOM   8947  C  CE2 . PHE D 1 278 ? 54.656  20.745  7.684   1.00 26.16  ? 278 PHE D CE2 1 
ATOM   8948  C  CZ  . PHE D 1 278 ? 53.709  19.747  7.816   1.00 26.38  ? 278 PHE D CZ  1 
ATOM   8949  N  N   . LEU D 1 279 ? 55.130  22.496  1.125   1.00 22.36  ? 279 LEU D N   1 
ATOM   8950  C  CA  . LEU D 1 279 ? 55.962  23.204  0.163   1.00 26.01  ? 279 LEU D CA  1 
ATOM   8951  C  C   . LEU D 1 279 ? 55.151  24.186  -0.681  1.00 27.89  ? 279 LEU D C   1 
ATOM   8952  O  O   . LEU D 1 279 ? 55.703  25.164  -1.173  1.00 32.08  ? 279 LEU D O   1 
ATOM   8953  C  CB  . LEU D 1 279 ? 56.694  22.218  -0.718  1.00 26.14  ? 279 LEU D CB  1 
ATOM   8954  C  CG  . LEU D 1 279 ? 57.614  21.245  0.010   1.00 26.24  ? 279 LEU D CG  1 
ATOM   8955  C  CD1 . LEU D 1 279 ? 58.252  20.342  -1.037  1.00 25.77  ? 279 LEU D CD1 1 
ATOM   8956  C  CD2 . LEU D 1 279 ? 58.642  21.967  0.895   1.00 27.00  ? 279 LEU D CD2 1 
ATOM   8957  N  N   . GLY D 1 280 ? 53.852  23.917  -0.832  1.00 26.07  ? 280 GLY D N   1 
ATOM   8958  C  CA  . GLY D 1 280 ? 53.005  24.804  -1.585  1.00 22.59  ? 280 GLY D CA  1 
ATOM   8959  C  C   . GLY D 1 280 ? 53.066  24.433  -3.052  1.00 22.70  ? 280 GLY D C   1 
ATOM   8960  O  O   . GLY D 1 280 ? 53.780  23.516  -3.422  1.00 23.42  ? 280 GLY D O   1 
ATOM   8961  N  N   . THR D 1 281 ? 52.274  25.151  -3.847  1.00 24.74  ? 281 THR D N   1 
ATOM   8962  C  CA  . THR D 1 281 ? 52.096  24.954  -5.275  1.00 21.90  ? 281 THR D CA  1 
ATOM   8963  C  C   . THR D 1 281 ? 52.238  26.306  -5.953  1.00 21.05  ? 281 THR D C   1 
ATOM   8964  O  O   . THR D 1 281 ? 52.507  27.303  -5.311  1.00 20.75  ? 281 THR D O   1 
ATOM   8965  C  CB  . THR D 1 281 ? 50.708  24.350  -5.525  1.00 20.44  ? 281 THR D CB  1 
ATOM   8966  O  OG1 . THR D 1 281 ? 49.670  25.283  -5.263  1.00 18.61  ? 281 THR D OG1 1 
ATOM   8967  C  CG2 . THR D 1 281 ? 50.494  23.112  -4.678  1.00 21.57  ? 281 THR D CG2 1 
ATOM   8968  N  N   . ALA D 1 282 ? 52.024  26.342  -7.252  1.00 23.44  ? 282 ALA D N   1 
ATOM   8969  C  CA  . ALA D 1 282 ? 52.002  27.620  -7.948  1.00 26.43  ? 282 ALA D CA  1 
ATOM   8970  C  C   . ALA D 1 282 ? 50.917  28.515  -7.357  1.00 24.14  ? 282 ALA D C   1 
ATOM   8971  O  O   . ALA D 1 282 ? 51.173  29.676  -7.145  1.00 21.15  ? 282 ALA D O   1 
ATOM   8972  C  CB  . ALA D 1 282 ? 51.794  27.382  -9.425  1.00 29.31  ? 282 ALA D CB  1 
ATOM   8973  N  N   . SER D 1 283 ? 49.749  27.950  -7.055  1.00 22.40  ? 283 SER D N   1 
ATOM   8974  C  CA  . SER D 1 283 ? 48.603  28.690  -6.574  1.00 25.88  ? 283 SER D CA  1 
ATOM   8975  C  C   . SER D 1 283 ? 48.592  28.978  -5.079  1.00 27.05  ? 283 SER D C   1 
ATOM   8976  O  O   . SER D 1 283 ? 47.784  29.797  -4.656  1.00 33.89  ? 283 SER D O   1 
ATOM   8977  C  CB  . SER D 1 283 ? 47.367  27.875  -6.772  1.00 28.40  ? 283 SER D CB  1 
ATOM   8978  O  OG  . SER D 1 283 ? 47.221  27.548  -8.123  1.00 32.33  ? 283 SER D OG  1 
ATOM   8979  N  N   . ALA D 1 284 ? 49.330  28.218  -4.261  1.00 23.44  ? 284 ALA D N   1 
ATOM   8980  C  CA  . ALA D 1 284 ? 49.109  28.274  -2.828  1.00 20.29  ? 284 ALA D CA  1 
ATOM   8981  C  C   . ALA D 1 284 ? 50.411  28.211  -2.064  1.00 19.86  ? 284 ALA D C   1 
ATOM   8982  O  O   . ALA D 1 284 ? 51.180  27.285  -2.212  1.00 22.84  ? 284 ALA D O   1 
ATOM   8983  C  CB  . ALA D 1 284 ? 48.233  27.144  -2.434  1.00 23.40  ? 284 ALA D CB  1 
ATOM   8984  N  N   . PRO D 1 285 ? 50.714  29.203  -1.211  1.00 20.12  ? 285 PRO D N   1 
ATOM   8985  C  CA  . PRO D 1 285 ? 51.997  29.236  -0.511  1.00 22.30  ? 285 PRO D CA  1 
ATOM   8986  C  C   . PRO D 1 285 ? 52.263  28.012  0.339   1.00 22.90  ? 285 PRO D C   1 
ATOM   8987  O  O   . PRO D 1 285 ? 53.386  27.517  0.409   1.00 21.72  ? 285 PRO D O   1 
ATOM   8988  C  CB  . PRO D 1 285 ? 51.866  30.500  0.380   1.00 25.62  ? 285 PRO D CB  1 
ATOM   8989  C  CG  . PRO D 1 285 ? 50.924  31.389  -0.414  1.00 23.65  ? 285 PRO D CG  1 
ATOM   8990  C  CD  . PRO D 1 285 ? 49.900  30.397  -0.956  1.00 21.74  ? 285 PRO D CD  1 
ATOM   8991  N  N   . HIS D 1 286 ? 51.191  27.579  1.022   1.00 22.85  ? 286 HIS D N   1 
ATOM   8992  C  CA  . HIS D 1 286 ? 51.187  26.385  1.856   1.00 22.81  ? 286 HIS D CA  1 
ATOM   8993  C  C   . HIS D 1 286 ? 49.772  26.250  2.396   1.00 22.34  ? 286 HIS D C   1 
ATOM   8994  O  O   . HIS D 1 286 ? 48.977  27.190  2.270   1.00 23.15  ? 286 HIS D O   1 
ATOM   8995  C  CB  . HIS D 1 286 ? 52.195  26.482  3.023   1.00 23.04  ? 286 HIS D CB  1 
ATOM   8996  C  CG  . HIS D 1 286 ? 51.990  27.682  3.907   1.00 24.27  ? 286 HIS D CG  1 
ATOM   8997  N  ND1 . HIS D 1 286 ? 52.755  28.826  3.813   1.00 21.34  ? 286 HIS D ND1 1 
ATOM   8998  C  CD2 . HIS D 1 286 ? 51.085  27.912  4.889   1.00 21.79  ? 286 HIS D CD2 1 
ATOM   8999  C  CE1 . HIS D 1 286 ? 52.327  29.685  4.713   1.00 22.59  ? 286 HIS D CE1 1 
ATOM   9000  N  NE2 . HIS D 1 286 ? 51.316  29.151  5.376   1.00 22.76  ? 286 HIS D NE2 1 
ATOM   9001  N  N   . ASP D 1 287 ? 49.490  25.094  3.008   1.00 21.67  ? 287 ASP D N   1 
ATOM   9002  C  CA  . ASP D 1 287 ? 48.204  24.832  3.630   1.00 21.21  ? 287 ASP D CA  1 
ATOM   9003  C  C   . ASP D 1 287 ? 48.068  25.758  4.841   1.00 21.79  ? 287 ASP D C   1 
ATOM   9004  O  O   . ASP D 1 287 ? 48.896  25.756  5.759   1.00 20.26  ? 287 ASP D O   1 
ATOM   9005  C  CB  . ASP D 1 287 ? 48.130  23.361  4.003   1.00 22.58  ? 287 ASP D CB  1 
ATOM   9006  C  CG  . ASP D 1 287 ? 46.797  22.825  4.510   1.00 23.21  ? 287 ASP D CG  1 
ATOM   9007  O  OD1 . ASP D 1 287 ? 45.963  23.635  4.974   1.00 24.46  ? 287 ASP D OD1 1 
ATOM   9008  O  OD2 . ASP D 1 287 ? 46.589  21.570  4.414   1.00 24.36  ? 287 ASP D OD2 1 
ATOM   9009  N  N   . ARG D 1 288 ? 47.000  26.544  4.855   1.00 20.76  ? 288 ARG D N   1 
ATOM   9010  C  CA  . ARG D 1 288 ? 46.738  27.460  5.951   1.00 20.35  ? 288 ARG D CA  1 
ATOM   9011  C  C   . ARG D 1 288 ? 46.555  26.747  7.294   1.00 19.74  ? 288 ARG D C   1 
ATOM   9012  O  O   . ARG D 1 288 ? 46.754  27.364  8.332   1.00 18.62  ? 288 ARG D O   1 
ATOM   9013  C  CB  . ARG D 1 288 ? 45.475  28.260  5.631   1.00 23.85  ? 288 ARG D CB  1 
ATOM   9014  C  CG  . ARG D 1 288 ? 45.707  29.267  4.516   1.00 27.30  ? 288 ARG D CG  1 
ATOM   9015  C  CD  . ARG D 1 288 ? 46.389  30.460  5.145   1.00 33.49  ? 288 ARG D CD  1 
ATOM   9016  N  NE  . ARG D 1 288 ? 45.422  31.235  5.941   1.00 43.92  ? 288 ARG D NE  1 
ATOM   9017  C  CZ  . ARG D 1 288 ? 45.588  31.742  7.179   1.00 44.31  ? 288 ARG D CZ  1 
ATOM   9018  N  NH1 . ARG D 1 288 ? 46.713  31.573  7.845   1.00 43.39  ? 288 ARG D NH1 1 
ATOM   9019  N  NH2 . ARG D 1 288 ? 44.617  32.400  7.769   1.00 40.80  ? 288 ARG D NH2 1 
ATOM   9020  N  N   . ILE D 1 289 ? 46.211  25.453  7.296   1.00 19.92  ? 289 ILE D N   1 
ATOM   9021  C  CA  . ILE D 1 289 ? 46.047  24.774  8.555   1.00 21.21  ? 289 ILE D CA  1 
ATOM   9022  C  C   . ILE D 1 289 ? 47.367  24.733  9.325   1.00 22.28  ? 289 ILE D C   1 
ATOM   9023  O  O   . ILE D 1 289 ? 47.338  24.616  10.563  1.00 19.68  ? 289 ILE D O   1 
ATOM   9024  C  CB  . ILE D 1 289 ? 45.438  23.382  8.345   1.00 23.88  ? 289 ILE D CB  1 
ATOM   9025  C  CG1 . ILE D 1 289 ? 44.600  22.949  9.571   1.00 23.66  ? 289 ILE D CG1 1 
ATOM   9026  C  CG2 . ILE D 1 289 ? 46.511  22.354  8.004   1.00 26.28  ? 289 ILE D CG2 1 
ATOM   9027  C  CD1 . ILE D 1 289 ? 43.990  21.548  9.458   1.00 23.82  ? 289 ILE D CD1 1 
ATOM   9028  N  N   . LEU D 1 290 ? 48.508  24.793  8.608   1.00 20.57  ? 290 LEU D N   1 
ATOM   9029  C  CA  . LEU D 1 290 ? 49.835  24.721  9.213   1.00 18.44  ? 290 LEU D CA  1 
ATOM   9030  C  C   . LEU D 1 290 ? 50.170  26.032  9.908   1.00 17.52  ? 290 LEU D C   1 
ATOM   9031  O  O   . LEU D 1 290 ? 51.095  26.084  10.716  1.00 19.18  ? 290 LEU D O   1 
ATOM   9032  C  CB  . LEU D 1 290 ? 50.900  24.377  8.163   1.00 19.44  ? 290 LEU D CB  1 
ATOM   9033  C  CG  . LEU D 1 290 ? 50.728  23.027  7.483   1.00 20.51  ? 290 LEU D CG  1 
ATOM   9034  C  CD1 . LEU D 1 290 ? 51.748  22.788  6.439   1.00 21.30  ? 290 LEU D CD1 1 
ATOM   9035  C  CD2 . LEU D 1 290 ? 50.737  21.890  8.500   1.00 22.99  ? 290 LEU D CD2 1 
ATOM   9036  N  N   . ASP D 1 291 ? 49.411  27.091  9.641   1.00 16.46  ? 291 ASP D N   1 
ATOM   9037  C  CA  . ASP D 1 291 ? 49.624  28.286  10.421  1.00 17.39  ? 291 ASP D CA  1 
ATOM   9038  C  C   . ASP D 1 291 ? 49.054  28.137  11.828  1.00 18.49  ? 291 ASP D C   1 
ATOM   9039  O  O   . ASP D 1 291 ? 49.189  29.036  12.636  1.00 21.20  ? 291 ASP D O   1 
ATOM   9040  C  CB  . ASP D 1 291 ? 49.083  29.534  9.733   1.00 21.22  ? 291 ASP D CB  1 
ATOM   9041  C  CG  . ASP D 1 291 ? 49.777  29.932  8.451   1.00 22.15  ? 291 ASP D CG  1 
ATOM   9042  O  OD1 . ASP D 1 291 ? 51.013  29.764  8.358   1.00 25.42  ? 291 ASP D OD1 1 
ATOM   9043  O  OD2 . ASP D 1 291 ? 49.049  30.305  7.522   1.00 27.37  ? 291 ASP D OD2 1 
ATOM   9044  N  N   . PHE D 1 292 ? 48.383  27.032  12.132  1.00 18.68  ? 292 PHE D N   1 
ATOM   9045  C  CA  . PHE D 1 292 ? 47.834  26.818  13.455  1.00 18.50  ? 292 PHE D CA  1 
ATOM   9046  C  C   . PHE D 1 292 ? 48.223  25.455  13.993  1.00 20.39  ? 292 PHE D C   1 
ATOM   9047  O  O   . PHE D 1 292 ? 47.748  25.072  15.055  1.00 22.89  ? 292 PHE D O   1 
ATOM   9048  C  CB  . PHE D 1 292 ? 46.310  26.905  13.423  1.00 19.23  ? 292 PHE D CB  1 
ATOM   9049  C  CG  . PHE D 1 292 ? 45.881  28.238  12.867  1.00 19.29  ? 292 PHE D CG  1 
ATOM   9050  C  CD1 . PHE D 1 292 ? 45.787  29.350  13.698  1.00 21.58  ? 292 PHE D CD1 1 
ATOM   9051  C  CD2 . PHE D 1 292 ? 45.632  28.378  11.505  1.00 19.56  ? 292 PHE D CD2 1 
ATOM   9052  C  CE1 . PHE D 1 292 ? 45.390  30.571  13.168  1.00 21.17  ? 292 PHE D CE1 1 
ATOM   9053  C  CE2 . PHE D 1 292 ? 45.259  29.590  10.989  1.00 19.14  ? 292 PHE D CE2 1 
ATOM   9054  C  CZ  . PHE D 1 292 ? 45.191  30.689  11.818  1.00 19.11  ? 292 PHE D CZ  1 
ATOM   9055  N  N   . SER D 1 293 ? 49.070  24.730  13.267  1.00 20.53  ? 293 SER D N   1 
ATOM   9056  C  CA  . SER D 1 293 ? 49.385  23.358  13.612  1.00 20.46  ? 293 SER D CA  1 
ATOM   9057  C  C   . SER D 1 293 ? 50.878  23.133  13.365  1.00 21.63  ? 293 SER D C   1 
ATOM   9058  O  O   . SER D 1 293 ? 51.317  23.420  12.263  1.00 25.16  ? 293 SER D O   1 
ATOM   9059  C  CB  . SER D 1 293 ? 48.554  22.412  12.784  1.00 19.18  ? 293 SER D CB  1 
ATOM   9060  O  OG  . SER D 1 293 ? 47.220  22.865  12.638  1.00 18.74  ? 293 SER D OG  1 
ATOM   9061  N  N   . THR D 1 294 ? 51.627  22.630  14.357  1.00 19.84  ? 294 THR D N   1 
ATOM   9062  C  CA  . THR D 1 294 ? 53.044  22.304  14.205  1.00 21.65  ? 294 THR D CA  1 
ATOM   9063  C  C   . THR D 1 294 ? 53.251  20.809  14.350  1.00 20.30  ? 294 THR D C   1 
ATOM   9064  O  O   . THR D 1 294 ? 52.858  20.256  15.382  1.00 18.13  ? 294 THR D O   1 
ATOM   9065  C  CB  . THR D 1 294 ? 53.851  22.976  15.302  1.00 22.15  ? 294 THR D CB  1 
ATOM   9066  O  OG1 . THR D 1 294 ? 53.489  24.339  15.297  1.00 23.00  ? 294 THR D OG1 1 
ATOM   9067  C  CG2 . THR D 1 294 ? 55.330  22.761  15.086  1.00 22.98  ? 294 THR D CG2 1 
ATOM   9068  N  N   . ALA D 1 295 ? 53.896  20.193  13.347  1.00 21.40  ? 295 ALA D N   1 
ATOM   9069  C  CA  . ALA D 1 295 ? 54.256  18.784  13.405  1.00 21.78  ? 295 ALA D CA  1 
ATOM   9070  C  C   . ALA D 1 295 ? 55.523  18.618  14.235  1.00 22.81  ? 295 ALA D C   1 
ATOM   9071  O  O   . ALA D 1 295 ? 56.520  19.293  13.997  1.00 24.48  ? 295 ALA D O   1 
ATOM   9072  C  CB  . ALA D 1 295 ? 54.449  18.229  12.026  1.00 21.32  ? 295 ALA D CB  1 
ATOM   9073  N  N   . VAL D 1 296 ? 55.479  17.712  15.208  1.00 23.66  ? 296 VAL D N   1 
ATOM   9074  C  CA  . VAL D 1 296 ? 56.621  17.459  16.085  1.00 19.87  ? 296 VAL D CA  1 
ATOM   9075  C  C   . VAL D 1 296 ? 57.096  16.015  15.944  1.00 20.54  ? 296 VAL D C   1 
ATOM   9076  O  O   . VAL D 1 296 ? 58.120  15.660  16.521  1.00 24.64  ? 296 VAL D O   1 
ATOM   9077  C  CB  . VAL D 1 296 ? 56.333  17.808  17.552  1.00 18.23  ? 296 VAL D CB  1 
ATOM   9078  C  CG1 . VAL D 1 296 ? 55.771  19.194  17.683  1.00 19.35  ? 296 VAL D CG1 1 
ATOM   9079  C  CG2 . VAL D 1 296 ? 55.339  16.892  18.207  1.00 18.97  ? 296 VAL D CG2 1 
ATOM   9080  N  N   . THR D 1 297 ? 56.367  15.179  15.188  1.00 19.60  ? 297 THR D N   1 
ATOM   9081  C  CA  . THR D 1 297 ? 56.867  13.864  14.827  1.00 18.65  ? 297 THR D CA  1 
ATOM   9082  C  C   . THR D 1 297 ? 56.505  13.613  13.380  1.00 19.04  ? 297 THR D C   1 
ATOM   9083  O  O   . THR D 1 297 ? 55.746  14.355  12.750  1.00 24.21  ? 297 THR D O   1 
ATOM   9084  C  CB  . THR D 1 297 ? 56.342  12.718  15.692  1.00 19.86  ? 297 THR D CB  1 
ATOM   9085  O  OG1 . THR D 1 297 ? 54.957  12.505  15.435  1.00 22.21  ? 297 THR D OG1 1 
ATOM   9086  C  CG2 . THR D 1 297 ? 56.563  12.981  17.155  1.00 19.67  ? 297 THR D CG2 1 
ATOM   9087  N  N   . GLY D 1 298 ? 57.180  12.596  12.859  1.00 18.54  ? 298 GLY D N   1 
ATOM   9088  C  CA  . GLY D 1 298 ? 56.951  12.140  11.508  1.00 19.23  ? 298 GLY D CA  1 
ATOM   9089  C  C   . GLY D 1 298 ? 57.596  10.778  11.296  1.00 18.80  ? 298 GLY D C   1 
ATOM   9090  O  O   . GLY D 1 298 ? 58.796  10.656  11.443  1.00 22.21  ? 298 GLY D O   1 
ATOM   9091  N  N   . SER D 1 299 ? 56.807  9.758   10.957  1.00 20.08  ? 299 SER D N   1 
ATOM   9092  C  CA  . SER D 1 299 ? 57.317  8.432   10.687  1.00 18.12  ? 299 SER D CA  1 
ATOM   9093  C  C   . SER D 1 299 ? 56.435  7.739   9.672   1.00 19.48  ? 299 SER D C   1 
ATOM   9094  O  O   . SER D 1 299 ? 55.247  8.041   9.561   1.00 22.57  ? 299 SER D O   1 
ATOM   9095  C  CB  . SER D 1 299 ? 57.362  7.625   11.927  1.00 18.84  ? 299 SER D CB  1 
ATOM   9096  O  OG  . SER D 1 299 ? 58.112  8.294   12.919  1.00 18.51  ? 299 SER D OG  1 
ATOM   9097  N  N   . LEU D 1 300 ? 57.046  6.782   8.965   1.00 19.70  ? 300 LEU D N   1 
ATOM   9098  C  CA  . LEU D 1 300 ? 56.378  5.977   7.960   1.00 19.38  ? 300 LEU D CA  1 
ATOM   9099  C  C   . LEU D 1 300 ? 56.568  4.510   8.310   1.00 19.75  ? 300 LEU D C   1 
ATOM   9100  O  O   . LEU D 1 300 ? 57.657  4.101   8.675   1.00 20.91  ? 300 LEU D O   1 
ATOM   9101  C  CB  . LEU D 1 300 ? 56.940  6.342   6.594   1.00 19.99  ? 300 LEU D CB  1 
ATOM   9102  C  CG  . LEU D 1 300 ? 56.216  5.763   5.370   1.00 25.05  ? 300 LEU D CG  1 
ATOM   9103  C  CD1 . LEU D 1 300 ? 56.587  6.456   4.084   1.00 27.01  ? 300 LEU D CD1 1 
ATOM   9104  C  CD2 . LEU D 1 300 ? 56.551  4.304   5.185   1.00 27.65  ? 300 LEU D CD2 1 
ATOM   9105  N  N   . PHE D 1 301 ? 55.504  3.722   8.171   1.00 19.24  ? 301 PHE D N   1 
ATOM   9106  C  CA  . PHE D 1 301 ? 55.533  2.312   8.521   1.00 19.56  ? 301 PHE D CA  1 
ATOM   9107  C  C   . PHE D 1 301 ? 54.779  1.513   7.473   1.00 23.41  ? 301 PHE D C   1 
ATOM   9108  O  O   . PHE D 1 301 ? 53.901  2.035   6.763   1.00 25.46  ? 301 PHE D O   1 
ATOM   9109  C  CB  . PHE D 1 301 ? 54.873  2.039   9.866   1.00 16.68  ? 301 PHE D CB  1 
ATOM   9110  C  CG  . PHE D 1 301 ? 55.460  2.870   10.994  1.00 16.70  ? 301 PHE D CG  1 
ATOM   9111  C  CD1 . PHE D 1 301 ? 55.015  4.153   11.275  1.00 17.04  ? 301 PHE D CD1 1 
ATOM   9112  C  CD2 . PHE D 1 301 ? 56.430  2.336   11.833  1.00 18.45  ? 301 PHE D CD2 1 
ATOM   9113  C  CE1 . PHE D 1 301 ? 55.501  4.872   12.359  1.00 16.75  ? 301 PHE D CE1 1 
ATOM   9114  C  CE2 . PHE D 1 301 ? 56.918  3.071   12.907  1.00 17.54  ? 301 PHE D CE2 1 
ATOM   9115  C  CZ  . PHE D 1 301 ? 56.453  4.341   13.157  1.00 15.77  ? 301 PHE D CZ  1 
ATOM   9116  N  N   . PHE D 1 302 ? 55.169  0.240   7.355   1.00 23.89  ? 302 PHE D N   1 
ATOM   9117  C  CA  . PHE D 1 302 ? 54.433  -0.723  6.561   1.00 23.63  ? 302 PHE D CA  1 
ATOM   9118  C  C   . PHE D 1 302 ? 53.695  -1.646  7.513   1.00 25.91  ? 302 PHE D C   1 
ATOM   9119  O  O   . PHE D 1 302 ? 54.285  -2.182  8.452   1.00 26.19  ? 302 PHE D O   1 
ATOM   9120  C  CB  . PHE D 1 302 ? 55.393  -1.494  5.668   1.00 24.76  ? 302 PHE D CB  1 
ATOM   9121  C  CG  . PHE D 1 302 ? 54.658  -2.510  4.818   1.00 25.36  ? 302 PHE D CG  1 
ATOM   9122  C  CD1 . PHE D 1 302 ? 53.918  -2.101  3.720   1.00 25.76  ? 302 PHE D CD1 1 
ATOM   9123  C  CD2 . PHE D 1 302 ? 54.715  -3.867  5.124   1.00 26.67  ? 302 PHE D CD2 1 
ATOM   9124  C  CE1 . PHE D 1 302 ? 53.228  -3.031  2.954   1.00 24.84  ? 302 PHE D CE1 1 
ATOM   9125  C  CE2 . PHE D 1 302 ? 54.046  -4.796  4.339   1.00 25.81  ? 302 PHE D CE2 1 
ATOM   9126  C  CZ  . PHE D 1 302 ? 53.294  -4.388  3.270   1.00 24.68  ? 302 PHE D CZ  1 
ATOM   9127  N  N   . THR D 1 303 ? 52.393  -1.788  7.283   1.00 27.24  ? 303 THR D N   1 
ATOM   9128  C  CA  . THR D 1 303 ? 51.565  -2.663  8.095   1.00 26.67  ? 303 THR D CA  1 
ATOM   9129  C  C   . THR D 1 303 ? 51.262  -3.894  7.243   1.00 27.01  ? 303 THR D C   1 
ATOM   9130  O  O   . THR D 1 303 ? 50.430  -3.840  6.337   1.00 27.83  ? 303 THR D O   1 
ATOM   9131  C  CB  . THR D 1 303 ? 50.282  -1.969  8.562   1.00 26.35  ? 303 THR D CB  1 
ATOM   9132  O  OG1 . THR D 1 303 ? 49.544  -1.505  7.440   1.00 28.25  ? 303 THR D OG1 1 
ATOM   9133  C  CG2 . THR D 1 303 ? 50.537  -0.684  9.305   1.00 27.70  ? 303 THR D CG2 1 
ATOM   9134  N  N   . PRO D 1 304 ? 51.933  -5.033  7.504   1.00 25.60  ? 304 PRO D N   1 
ATOM   9135  C  CA  . PRO D 1 304 ? 51.772  -6.230  6.691   1.00 26.72  ? 304 PRO D CA  1 
ATOM   9136  C  C   . PRO D 1 304 ? 50.397  -6.840  6.822   1.00 29.90  ? 304 PRO D C   1 
ATOM   9137  O  O   . PRO D 1 304 ? 49.659  -6.545  7.771   1.00 34.04  ? 304 PRO D O   1 
ATOM   9138  C  CB  . PRO D 1 304 ? 52.817  -7.190  7.238   1.00 28.60  ? 304 PRO D CB  1 
ATOM   9139  C  CG  . PRO D 1 304 ? 53.700  -6.396  8.147   1.00 28.68  ? 304 PRO D CG  1 
ATOM   9140  C  CD  . PRO D 1 304 ? 52.897  -5.217  8.593   1.00 29.91  ? 304 PRO D CD  1 
ATOM   9141  N  N   . ALA D 1 305 ? 50.096  -7.734  5.873   1.00 32.59  ? 305 ALA D N   1 
ATOM   9142  C  CA  . ALA D 1 305 ? 48.948  -8.611  6.041   1.00 35.42  ? 305 ALA D CA  1 
ATOM   9143  C  C   . ALA D 1 305 ? 49.126  -9.410  7.331   1.00 38.85  ? 305 ALA D C   1 
ATOM   9144  O  O   . ALA D 1 305 ? 50.240  -9.692  7.746   1.00 41.45  ? 305 ALA D O   1 
ATOM   9145  C  CB  . ALA D 1 305 ? 48.762  -9.513  4.835   1.00 38.42  ? 305 ALA D CB  1 
ATOM   9146  N  N   . ALA D 1 306 ? 48.005  -9.763  7.959   1.00 40.16  ? 306 ALA D N   1 
ATOM   9147  C  CA  . ALA D 1 306 ? 48.008  -10.503 9.205   1.00 38.92  ? 306 ALA D CA  1 
ATOM   9148  C  C   . ALA D 1 306 ? 48.711  -11.847 9.034   1.00 40.32  ? 306 ALA D C   1 
ATOM   9149  O  O   . ALA D 1 306 ? 49.445  -12.206 9.934   1.00 43.97  ? 306 ALA D O   1 
ATOM   9150  C  CB  . ALA D 1 306 ? 46.599  -10.676 9.671   1.00 38.63  ? 306 ALA D CB  1 
ATOM   9151  N  N   . ASP D 1 307 ? 48.533  -12.554 7.904   1.00 43.26  ? 307 ASP D N   1 
ATOM   9152  C  CA  . ASP D 1 307 ? 49.180  -13.843 7.649   1.00 50.36  ? 307 ASP D CA  1 
ATOM   9153  C  C   . ASP D 1 307 ? 50.693  -13.742 7.771   1.00 45.87  ? 307 ASP D C   1 
ATOM   9154  O  O   . ASP D 1 307 ? 51.329  -14.647 8.310   1.00 53.47  ? 307 ASP D O   1 
ATOM   9155  C  CB  . ASP D 1 307 ? 49.016  -14.364 6.232   1.00 57.47  ? 307 ASP D CB  1 
ATOM   9156  C  CG  . ASP D 1 307 ? 47.703  -13.972 5.588   1.00 74.62  ? 307 ASP D CG  1 
ATOM   9157  O  OD1 . ASP D 1 307 ? 46.664  -14.490 6.065   1.00 64.84  ? 307 ASP D OD1 1 
ATOM   9158  O  OD2 . ASP D 1 307 ? 47.760  -13.124 4.664   1.00 88.04  ? 307 ASP D OD2 1 
ATOM   9159  N  N   . PHE D 1 308 ? 51.243  -12.642 7.245   1.00 41.39  ? 308 PHE D N   1 
ATOM   9160  C  CA  . PHE D 1 308 ? 52.681  -12.411 7.292   1.00 37.59  ? 308 PHE D CA  1 
ATOM   9161  C  C   . PHE D 1 308 ? 53.201  -12.487 8.735   1.00 38.66  ? 308 PHE D C   1 
ATOM   9162  O  O   . PHE D 1 308 ? 54.253  -13.075 8.983   1.00 43.61  ? 308 PHE D O   1 
ATOM   9163  C  CB  . PHE D 1 308 ? 53.052  -11.087 6.626   1.00 35.72  ? 308 PHE D CB  1 
ATOM   9164  C  CG  . PHE D 1 308 ? 54.543  -10.795 6.611   1.00 39.75  ? 308 PHE D CG  1 
ATOM   9165  C  CD1 . PHE D 1 308 ? 55.346  -11.285 5.581   1.00 45.25  ? 308 PHE D CD1 1 
ATOM   9166  C  CD2 . PHE D 1 308 ? 55.145  -10.027 7.609   1.00 41.20  ? 308 PHE D CD2 1 
ATOM   9167  C  CE1 . PHE D 1 308 ? 56.712  -11.007 5.540   1.00 46.08  ? 308 PHE D CE1 1 
ATOM   9168  C  CE2 . PHE D 1 308 ? 56.513  -9.772  7.569   1.00 46.78  ? 308 PHE D CE2 1 
ATOM   9169  C  CZ  . PHE D 1 308 ? 57.291  -10.264 6.536   1.00 46.73  ? 308 PHE D CZ  1 
ATOM   9170  N  N   . LEU D 1 309 ? 52.482  -11.894 9.697   1.00 38.00  ? 309 LEU D N   1 
ATOM   9171  C  CA  . LEU D 1 309 ? 52.909  -11.879 11.093  1.00 37.11  ? 309 LEU D CA  1 
ATOM   9172  C  C   . LEU D 1 309 ? 52.721  -13.251 11.753  1.00 42.27  ? 309 LEU D C   1 
ATOM   9173  O  O   . LEU D 1 309 ? 53.547  -13.614 12.593  1.00 41.96  ? 309 LEU D O   1 
ATOM   9174  C  CB  . LEU D 1 309 ? 52.163  -10.798 11.874  1.00 39.45  ? 309 LEU D CB  1 
ATOM   9175  C  CG  . LEU D 1 309 ? 52.356  -9.344  11.434  1.00 37.74  ? 309 LEU D CG  1 
ATOM   9176  C  CD1 . LEU D 1 309 ? 51.361  -8.491  12.116  1.00 38.61  ? 309 LEU D CD1 1 
ATOM   9177  C  CD2 . LEU D 1 309 ? 53.720  -8.825  11.757  1.00 39.58  ? 309 LEU D CD2 1 
ATOM   9178  N  N   . GLU D 1 310 ? 51.648  -13.996 11.387  1.00 50.98  ? 310 GLU D N   1 
ATOM   9179  C  CA  . GLU D 1 310 ? 51.322  -15.301 11.975  1.00 56.94  ? 310 GLU D CA  1 
ATOM   9180  C  C   . GLU D 1 310 ? 52.575  -16.171 11.819  1.00 60.72  ? 310 GLU D C   1 
ATOM   9181  O  O   . GLU D 1 310 ? 53.050  -16.755 12.802  1.00 64.23  ? 310 GLU D O   1 
ATOM   9182  C  CB  . GLU D 1 310 ? 50.026  -15.963 11.458  1.00 41.42  ? 310 GLU D CB  1 
ATOM   9183  N  N   . ASP D 1 311 ? 53.170  -16.175 10.617  1.00 52.84  ? 311 ASP D N   1 
ATOM   9184  C  CA  . ASP D 1 311 ? 54.049  -17.286 10.287  1.00 72.22  ? 311 ASP D CA  1 
ATOM   9185  C  C   . ASP D 1 311 ? 55.469  -16.722 10.190  1.00 77.22  ? 311 ASP D C   1 
ATOM   9186  O  O   . ASP D 1 311 ? 55.879  -16.258 9.120   1.00 68.79  ? 311 ASP D O   1 
ATOM   9187  C  CB  . ASP D 1 311 ? 53.326  -18.314 9.408   1.00 79.10  ? 311 ASP D CB  1 
ATOM   9188  C  CG  . ASP D 1 311 ? 52.505  -17.803 8.229   1.00 83.62  ? 311 ASP D CG  1 
ATOM   9189  O  OD1 . ASP D 1 311 ? 53.169  -17.220 7.369   1.00 90.09  ? 311 ASP D OD1 1 
ATOM   9190  O  OD2 . ASP D 1 311 ? 51.250  -18.041 8.148   1.00 75.67  ? 311 ASP D OD2 1 
ATOM   9191  N  N   . LEU D 1 312 ? 56.177  -16.781 11.346  1.00 84.19  ? 312 LEU D N   1 
ATOM   9192  C  CA  . LEU D 1 312 ? 57.558  -16.302 11.462  1.00 92.12  ? 312 LEU D CA  1 
ATOM   9193  C  C   . LEU D 1 312 ? 58.549  -17.324 12.083  1.00 87.69  ? 312 LEU D C   1 
ATOM   9194  O  O   . LEU D 1 312 ? 58.097  -18.315 12.683  1.00 96.29  ? 312 LEU D O   1 
ATOM   9195  C  CB  . LEU D 1 312 ? 57.533  -14.993 12.256  1.00 83.56  ? 312 LEU D CB  1 
ATOM   9196  C  CG  . LEU D 1 312 ? 57.090  -13.715 11.522  1.00 67.97  ? 312 LEU D CG  1 
ATOM   9197  C  CD1 . LEU D 1 312 ? 57.721  -12.541 12.267  1.00 58.76  ? 312 LEU D CD1 1 
ATOM   9198  C  CD2 . LEU D 1 312 ? 57.406  -13.586 10.031  1.00 63.11  ? 312 LEU D CD2 1 
ATOM   9199  N  N   . GLU E 1 7   ? 13.990  6.837   58.224  1.00 69.10  ? 7   GLU E N   1 
ATOM   9200  C  CA  . GLU E 1 7   ? 13.511  5.435   58.101  1.00 76.95  ? 7   GLU E CA  1 
ATOM   9201  C  C   . GLU E 1 7   ? 14.606  4.468   58.598  1.00 77.16  ? 7   GLU E C   1 
ATOM   9202  O  O   . GLU E 1 7   ? 15.622  4.865   59.197  1.00 61.91  ? 7   GLU E O   1 
ATOM   9203  C  CB  . GLU E 1 7   ? 12.932  5.266   56.683  1.00 67.65  ? 7   GLU E CB  1 
ATOM   9204  N  N   . PRO E 1 8   ? 14.285  3.149   58.571  1.00 86.13  ? 8   PRO E N   1 
ATOM   9205  C  CA  . PRO E 1 8   ? 15.245  2.092   58.208  1.00 69.33  ? 8   PRO E CA  1 
ATOM   9206  C  C   . PRO E 1 8   ? 15.213  1.754   56.708  1.00 57.54  ? 8   PRO E C   1 
ATOM   9207  O  O   . PRO E 1 8   ? 14.207  2.059   56.071  1.00 45.01  ? 8   PRO E O   1 
ATOM   9208  C  CB  . PRO E 1 8   ? 14.711  0.932   59.105  1.00 73.10  ? 8   PRO E CB  1 
ATOM   9209  C  CG  . PRO E 1 8   ? 13.196  1.132   59.173  1.00 73.88  ? 8   PRO E CG  1 
ATOM   9210  C  CD  . PRO E 1 8   ? 12.980  2.626   59.055  1.00 77.89  ? 8   PRO E CD  1 
ATOM   9211  N  N   . GLU E 1 9   ? 16.293  1.154   56.167  1.00 57.64  ? 9   GLU E N   1 
ATOM   9212  C  CA  . GLU E 1 9   ? 16.398  0.738   54.762  1.00 58.52  ? 9   GLU E CA  1 
ATOM   9213  C  C   . GLU E 1 9   ? 15.512  -0.517  54.585  1.00 50.90  ? 9   GLU E C   1 
ATOM   9214  O  O   . GLU E 1 9   ? 15.702  -1.558  55.230  1.00 44.76  ? 9   GLU E O   1 
ATOM   9215  C  CB  . GLU E 1 9   ? 17.858  0.608   54.251  1.00 46.04  ? 9   GLU E CB  1 
ATOM   9216  N  N   . PRO E 1 10  ? 14.479  -0.496  53.711  1.00 39.91  ? 10  PRO E N   1 
ATOM   9217  C  CA  . PRO E 1 10  ? 13.856  -1.736  53.234  1.00 39.02  ? 10  PRO E CA  1 
ATOM   9218  C  C   . PRO E 1 10  ? 14.762  -2.509  52.287  1.00 35.51  ? 10  PRO E C   1 
ATOM   9219  O  O   . PRO E 1 10  ? 15.711  -1.960  51.733  1.00 34.25  ? 10  PRO E O   1 
ATOM   9220  C  CB  . PRO E 1 10  ? 12.603  -1.261  52.474  1.00 34.58  ? 10  PRO E CB  1 
ATOM   9221  C  CG  . PRO E 1 10  ? 13.011  0.098   51.980  1.00 33.67  ? 10  PRO E CG  1 
ATOM   9222  C  CD  . PRO E 1 10  ? 13.879  0.687   53.091  1.00 35.99  ? 10  PRO E CD  1 
ATOM   9223  N  N   . GLN E 1 11  ? 14.430  -3.784  52.083  1.00 37.97  ? 11  GLN E N   1 
ATOM   9224  C  CA  . GLN E 1 11  ? 15.052  -4.572  51.040  1.00 31.68  ? 11  GLN E CA  1 
ATOM   9225  C  C   . GLN E 1 11  ? 14.583  -3.976  49.715  1.00 36.13  ? 11  GLN E C   1 
ATOM   9226  O  O   . GLN E 1 11  ? 13.712  -3.093  49.706  1.00 32.15  ? 11  GLN E O   1 
ATOM   9227  C  CB  . GLN E 1 11  ? 14.700  -6.063  51.189  1.00 29.16  ? 11  GLN E CB  1 
ATOM   9228  C  CG  . GLN E 1 11  ? 15.309  -6.748  52.402  1.00 25.58  ? 11  GLN E CG  1 
ATOM   9229  C  CD  . GLN E 1 11  ? 15.023  -8.229  52.396  1.00 27.35  ? 11  GLN E CD  1 
ATOM   9230  O  OE1 . GLN E 1 11  ? 15.481  -9.001  51.547  1.00 31.88  ? 11  GLN E OE1 1 
ATOM   9231  N  NE2 . GLN E 1 11  ? 14.226  -8.652  53.349  1.00 27.59  ? 11  GLN E NE2 1 
ATOM   9232  N  N   . MET E 1 12  ? 15.100  -4.527  48.606  1.00 39.59  ? 12  MET E N   1 
ATOM   9233  C  CA  . MET E 1 12  ? 14.766  -4.031  47.283  1.00 42.52  ? 12  MET E CA  1 
ATOM   9234  C  C   . MET E 1 12  ? 13.411  -4.565  46.818  1.00 36.17  ? 12  MET E C   1 
ATOM   9235  O  O   . MET E 1 12  ? 13.297  -5.152  45.754  1.00 35.18  ? 12  MET E O   1 
ATOM   9236  C  CB  . MET E 1 12  ? 15.866  -4.382  46.273  1.00 50.42  ? 12  MET E CB  1 
ATOM   9237  C  CG  . MET E 1 12  ? 15.867  -3.511  45.008  1.00 63.57  ? 12  MET E CG  1 
ATOM   9238  S  SD  . MET E 1 12  ? 15.925  -1.717  45.308  1.00 68.51  ? 12  MET E SD  1 
ATOM   9239  C  CE  . MET E 1 12  ? 16.996  -1.571  46.754  1.00 58.50  ? 12  MET E CE  1 
ATOM   9240  N  N   . VAL E 1 13  ? 12.359  -4.268  47.571  1.00 34.55  ? 13  VAL E N   1 
ATOM   9241  C  CA  . VAL E 1 13  ? 11.048  -4.754  47.195  1.00 37.45  ? 13  VAL E CA  1 
ATOM   9242  C  C   . VAL E 1 13  ? 10.594  -4.009  45.949  1.00 42.99  ? 13  VAL E C   1 
ATOM   9243  O  O   . VAL E 1 13  ? 10.153  -4.638  45.002  1.00 41.38  ? 13  VAL E O   1 
ATOM   9244  C  CB  . VAL E 1 13  ? 10.040  -4.627  48.349  1.00 39.74  ? 13  VAL E CB  1 
ATOM   9245  C  CG1 . VAL E 1 13  ? 8.640   -4.999  47.909  1.00 44.19  ? 13  VAL E CG1 1 
ATOM   9246  C  CG2 . VAL E 1 13  ? 10.438  -5.478  49.542  1.00 38.75  ? 13  VAL E CG2 1 
ATOM   9247  N  N   . LEU E 1 14  ? 10.726  -2.672  45.959  1.00 47.73  ? 14  LEU E N   1 
ATOM   9248  C  CA  . LEU E 1 14  ? 10.446  -1.836  44.794  1.00 48.05  ? 14  LEU E CA  1 
ATOM   9249  C  C   . LEU E 1 14  ? 11.693  -1.873  43.911  1.00 46.01  ? 14  LEU E C   1 
ATOM   9250  O  O   . LEU E 1 14  ? 12.659  -1.157  44.104  1.00 43.40  ? 14  LEU E O   1 
ATOM   9251  C  CB  . LEU E 1 14  ? 10.095  -0.410  45.204  1.00 43.43  ? 14  LEU E CB  1 
ATOM   9252  C  CG  . LEU E 1 14  ? 9.213   -0.300  46.448  1.00 44.00  ? 14  LEU E CG  1 
ATOM   9253  C  CD1 . LEU E 1 14  ? 9.295   0.994   47.270  1.00 47.28  ? 14  LEU E CD1 1 
ATOM   9254  C  CD2 . LEU E 1 14  ? 7.820   -0.529  45.947  1.00 47.55  ? 14  LEU E CD2 1 
ATOM   9255  N  N   . SER E 1 15  ? 11.687  -2.767  42.948  1.00 48.15  ? 15  SER E N   1 
ATOM   9256  C  CA  . SER E 1 15  ? 12.827  -2.938  42.088  1.00 55.49  ? 15  SER E CA  1 
ATOM   9257  C  C   . SER E 1 15  ? 12.457  -2.289  40.758  1.00 59.37  ? 15  SER E C   1 
ATOM   9258  O  O   . SER E 1 15  ? 11.277  -2.195  40.420  1.00 49.99  ? 15  SER E O   1 
ATOM   9259  C  CB  . SER E 1 15  ? 13.152  -4.427  41.994  1.00 60.53  ? 15  SER E CB  1 
ATOM   9260  O  OG  . SER E 1 15  ? 13.688  -4.837  40.744  1.00 62.38  ? 15  SER E OG  1 
ATOM   9261  N  N   . PRO E 1 16  ? 13.434  -1.750  39.992  1.00 64.45  ? 16  PRO E N   1 
ATOM   9262  C  CA  . PRO E 1 16  ? 13.185  -1.460  38.580  1.00 58.48  ? 16  PRO E CA  1 
ATOM   9263  C  C   . PRO E 1 16  ? 12.545  -2.651  37.871  1.00 60.15  ? 16  PRO E C   1 
ATOM   9264  O  O   . PRO E 1 16  ? 12.505  -3.750  38.418  1.00 64.73  ? 16  PRO E O   1 
ATOM   9265  C  CB  . PRO E 1 16  ? 14.586  -1.151  38.027  1.00 63.64  ? 16  PRO E CB  1 
ATOM   9266  C  CG  . PRO E 1 16  ? 15.569  -1.514  39.154  1.00 64.78  ? 16  PRO E CG  1 
ATOM   9267  C  CD  . PRO E 1 16  ? 14.790  -1.370  40.445  1.00 63.84  ? 16  PRO E CD  1 
ATOM   9268  N  N   . LEU E 1 17  ? 12.052  -2.414  36.652  1.00 66.14  ? 17  LEU E N   1 
ATOM   9269  C  CA  . LEU E 1 17  ? 11.686  -3.488  35.743  1.00 65.29  ? 17  LEU E CA  1 
ATOM   9270  C  C   . LEU E 1 17  ? 12.927  -4.361  35.498  1.00 61.11  ? 17  LEU E C   1 
ATOM   9271  O  O   . LEU E 1 17  ? 14.028  -3.835  35.266  1.00 61.29  ? 17  LEU E O   1 
ATOM   9272  C  CB  . LEU E 1 17  ? 11.071  -2.909  34.464  1.00 72.73  ? 17  LEU E CB  1 
ATOM   9273  C  CG  . LEU E 1 17  ? 9.565   -2.618  34.523  1.00 74.90  ? 17  LEU E CG  1 
ATOM   9274  C  CD1 . LEU E 1 17  ? 9.121   -1.780  33.326  1.00 75.79  ? 17  LEU E CD1 1 
ATOM   9275  C  CD2 . LEU E 1 17  ? 8.769   -3.925  34.618  1.00 70.17  ? 17  LEU E CD2 1 
ATOM   9276  N  N   . THR E 1 18  ? 12.751  -5.678  35.692  1.00 42.41  ? 18  THR E N   1 
ATOM   9277  C  CA  . THR E 1 18  ? 13.796  -6.665  35.478  1.00 41.02  ? 18  THR E CA  1 
ATOM   9278  C  C   . THR E 1 18  ? 13.174  -7.768  34.641  1.00 37.44  ? 18  THR E C   1 
ATOM   9279  O  O   . THR E 1 18  ? 11.985  -7.980  34.710  1.00 38.41  ? 18  THR E O   1 
ATOM   9280  C  CB  . THR E 1 18  ? 14.339  -7.241  36.792  1.00 41.17  ? 18  THR E CB  1 
ATOM   9281  O  OG1 . THR E 1 18  ? 13.210  -7.704  37.522  1.00 42.94  ? 18  THR E OG1 1 
ATOM   9282  C  CG2 . THR E 1 18  ? 15.087  -6.238  37.643  1.00 37.35  ? 18  THR E CG2 1 
ATOM   9283  N  N   . SER E 1 19  ? 13.975  -8.480  33.862  1.00 31.69  ? 19  SER E N   1 
ATOM   9284  C  CA  . SER E 1 19  ? 13.421  -9.378  32.868  1.00 32.10  ? 19  SER E CA  1 
ATOM   9285  C  C   . SER E 1 19  ? 13.715  -10.834 33.214  1.00 29.91  ? 19  SER E C   1 
ATOM   9286  O  O   . SER E 1 19  ? 13.266  -11.744 32.531  1.00 28.56  ? 19  SER E O   1 
ATOM   9287  C  CB  . SER E 1 19  ? 13.970  -8.995  31.518  1.00 33.41  ? 19  SER E CB  1 
ATOM   9288  O  OG  . SER E 1 19  ? 15.146  -8.214  31.717  1.00 32.43  ? 19  SER E OG  1 
ATOM   9289  N  N   . ALA E 1 20  ? 14.469  -11.076 34.285  1.00 24.22  ? 20  ALA E N   1 
ATOM   9290  C  CA  . ALA E 1 20  ? 14.781  -12.438 34.691  1.00 20.52  ? 20  ALA E CA  1 
ATOM   9291  C  C   . ALA E 1 20  ? 14.668  -12.542 36.207  1.00 19.25  ? 20  ALA E C   1 
ATOM   9292  O  O   . ALA E 1 20  ? 14.909  -11.583 36.927  1.00 18.38  ? 20  ALA E O   1 
ATOM   9293  C  CB  . ALA E 1 20  ? 16.170  -12.805 34.236  1.00 19.72  ? 20  ALA E CB  1 
ATOM   9294  N  N   . ALA E 1 21  ? 14.320  -13.737 36.684  1.00 21.14  ? 21  ALA E N   1 
ATOM   9295  C  CA  . ALA E 1 21  ? 14.154  -13.975 38.099  1.00 20.70  ? 21  ALA E CA  1 
ATOM   9296  C  C   . ALA E 1 21  ? 14.420  -15.428 38.403  1.00 21.02  ? 21  ALA E C   1 
ATOM   9297  O  O   . ALA E 1 21  ? 14.193  -16.305 37.586  1.00 19.74  ? 21  ALA E O   1 
ATOM   9298  C  CB  . ALA E 1 21  ? 12.772  -13.604 38.566  1.00 22.00  ? 21  ALA E CB  1 
ATOM   9299  N  N   . ILE E 1 22  ? 14.923  -15.644 39.612  1.00 22.97  ? 22  ILE E N   1 
ATOM   9300  C  CA  . ILE E 1 22  ? 14.926  -16.953 40.218  1.00 24.34  ? 22  ILE E CA  1 
ATOM   9301  C  C   . ILE E 1 22  ? 14.146  -16.822 41.521  1.00 24.55  ? 22  ILE E C   1 
ATOM   9302  O  O   . ILE E 1 22  ? 14.407  -15.933 42.312  1.00 24.16  ? 22  ILE E O   1 
ATOM   9303  C  CB  . ILE E 1 22  ? 16.354  -17.494 40.428  1.00 25.30  ? 22  ILE E CB  1 
ATOM   9304  C  CG1 . ILE E 1 22  ? 16.960  -17.986 39.129  1.00 23.37  ? 22  ILE E CG1 1 
ATOM   9305  C  CG2 . ILE E 1 22  ? 16.355  -18.605 41.475  1.00 27.20  ? 22  ILE E CG2 1 
ATOM   9306  C  CD1 . ILE E 1 22  ? 18.424  -18.364 39.250  1.00 22.75  ? 22  ILE E CD1 1 
ATOM   9307  N  N   . PHE E 1 23  ? 13.185  -17.726 41.693  1.00 24.17  ? 23  PHE E N   1 
ATOM   9308  C  CA  . PHE E 1 23  ? 12.494  -17.921 42.953  1.00 25.28  ? 23  PHE E CA  1 
ATOM   9309  C  C   . PHE E 1 23  ? 12.972  -19.241 43.565  1.00 23.10  ? 23  PHE E C   1 
ATOM   9310  O  O   . PHE E 1 23  ? 12.887  -20.329 42.975  1.00 21.29  ? 23  PHE E O   1 
ATOM   9311  C  CB  . PHE E 1 23  ? 10.973  -17.975 42.816  1.00 25.34  ? 23  PHE E CB  1 
ATOM   9312  C  CG  . PHE E 1 23  ? 10.377  -16.795 42.086  1.00 21.63  ? 23  PHE E CG  1 
ATOM   9313  C  CD1 . PHE E 1 23  ? 10.245  -16.791 40.711  1.00 22.05  ? 23  PHE E CD1 1 
ATOM   9314  C  CD2 . PHE E 1 23  ? 9.924   -15.714 42.785  1.00 20.27  ? 23  PHE E CD2 1 
ATOM   9315  C  CE1 . PHE E 1 23  ? 9.709   -15.696 40.044  1.00 21.55  ? 23  PHE E CE1 1 
ATOM   9316  C  CE2 . PHE E 1 23  ? 9.331   -14.664 42.117  1.00 20.65  ? 23  PHE E CE2 1 
ATOM   9317  C  CZ  . PHE E 1 23  ? 9.249   -14.647 40.746  1.00 20.34  ? 23  PHE E CZ  1 
ATOM   9318  N  N   . LEU E 1 24  ? 13.468  -19.119 44.789  1.00 22.33  ? 24  LEU E N   1 
ATOM   9319  C  CA  . LEU E 1 24  ? 13.919  -20.253 45.561  1.00 24.95  ? 24  LEU E CA  1 
ATOM   9320  C  C   . LEU E 1 24  ? 13.120  -20.321 46.858  1.00 24.41  ? 24  LEU E C   1 
ATOM   9321  O  O   . LEU E 1 24  ? 13.072  -19.334 47.607  1.00 22.58  ? 24  LEU E O   1 
ATOM   9322  C  CB  . LEU E 1 24  ? 15.375  -19.885 45.780  1.00 29.37  ? 24  LEU E CB  1 
ATOM   9323  C  CG  . LEU E 1 24  ? 16.329  -21.017 46.102  1.00 36.88  ? 24  LEU E CG  1 
ATOM   9324  C  CD1 . LEU E 1 24  ? 16.299  -22.073 44.987  1.00 40.00  ? 24  LEU E CD1 1 
ATOM   9325  C  CD2 . LEU E 1 24  ? 17.687  -20.349 46.266  1.00 41.86  ? 24  LEU E CD2 1 
ATOM   9326  N  N   . VAL E 1 25  ? 12.455  -21.463 47.087  1.00 22.51  ? 25  VAL E N   1 
ATOM   9327  C  CA  . VAL E 1 25  ? 11.806  -21.724 48.355  1.00 22.16  ? 25  VAL E CA  1 
ATOM   9328  C  C   . VAL E 1 25  ? 12.418  -22.940 49.013  1.00 22.12  ? 25  VAL E C   1 
ATOM   9329  O  O   . VAL E 1 25  ? 12.520  -23.983 48.411  1.00 26.06  ? 25  VAL E O   1 
ATOM   9330  C  CB  . VAL E 1 25  ? 10.302  -21.895 48.197  1.00 23.08  ? 25  VAL E CB  1 
ATOM   9331  C  CG1 . VAL E 1 25  ? 9.666   -22.182 49.542  1.00 25.86  ? 25  VAL E CG1 1 
ATOM   9332  C  CG2 . VAL E 1 25  ? 9.668   -20.630 47.625  1.00 24.79  ? 25  VAL E CG2 1 
ATOM   9333  N  N   . VAL E 1 26  ? 12.832  -22.799 50.258  1.00 24.16  ? 26  VAL E N   1 
ATOM   9334  C  CA  . VAL E 1 26  ? 13.450  -23.906 50.988  1.00 26.82  ? 26  VAL E CA  1 
ATOM   9335  C  C   . VAL E 1 26  ? 12.827  -24.057 52.377  1.00 23.32  ? 26  VAL E C   1 
ATOM   9336  O  O   . VAL E 1 26  ? 12.215  -23.132 52.908  1.00 21.12  ? 26  VAL E O   1 
ATOM   9337  C  CB  . VAL E 1 26  ? 14.978  -23.689 51.081  1.00 25.53  ? 26  VAL E CB  1 
ATOM   9338  C  CG1 . VAL E 1 26  ? 15.598  -23.557 49.694  1.00 27.91  ? 26  VAL E CG1 1 
ATOM   9339  C  CG2 . VAL E 1 26  ? 15.354  -22.487 51.930  1.00 23.50  ? 26  VAL E CG2 1 
ATOM   9340  N  N   . THR E 1 27  ? 13.001  -25.245 52.946  1.00 22.93  ? 27  THR E N   1 
ATOM   9341  C  CA  . THR E 1 27  ? 12.712  -25.480 54.356  1.00 25.31  ? 27  THR E CA  1 
ATOM   9342  C  C   . THR E 1 27  ? 14.014  -25.732 55.097  1.00 25.01  ? 27  THR E C   1 
ATOM   9343  O  O   . THR E 1 27  ? 14.976  -26.242 54.523  1.00 28.70  ? 27  THR E O   1 
ATOM   9344  C  CB  . THR E 1 27  ? 11.760  -26.660 54.519  1.00 25.02  ? 27  THR E CB  1 
ATOM   9345  O  OG1 . THR E 1 27  ? 12.355  -27.766 53.849  1.00 25.47  ? 27  THR E OG1 1 
ATOM   9346  C  CG2 . THR E 1 27  ? 10.392  -26.324 53.953  1.00 25.35  ? 27  THR E CG2 1 
ATOM   9347  N  N   . ILE E 1 28  ? 14.020  -25.362 56.364  1.00 22.45  ? 28  ILE E N   1 
ATOM   9348  C  CA  . ILE E 1 28  ? 15.196  -25.472 57.202  1.00 20.71  ? 28  ILE E CA  1 
ATOM   9349  C  C   . ILE E 1 28  ? 15.191  -26.814 57.919  1.00 21.44  ? 28  ILE E C   1 
ATOM   9350  O  O   . ILE E 1 28  ? 14.289  -27.135 58.690  1.00 22.32  ? 28  ILE E O   1 
ATOM   9351  C  CB  . ILE E 1 28  ? 15.207  -24.325 58.213  1.00 21.44  ? 28  ILE E CB  1 
ATOM   9352  C  CG1 . ILE E 1 28  ? 15.048  -22.955 57.584  1.00 20.77  ? 28  ILE E CG1 1 
ATOM   9353  C  CG2 . ILE E 1 28  ? 16.475  -24.408 59.037  1.00 22.95  ? 28  ILE E CG2 1 
ATOM   9354  C  CD1 . ILE E 1 28  ? 14.773  -21.875 58.614  1.00 21.54  ? 28  ILE E CD1 1 
ATOM   9355  N  N   . ASP E 1 29  ? 16.233  -27.591 57.714  1.00 22.16  ? 29  ASP E N   1 
ATOM   9356  C  CA  . ASP E 1 29  ? 16.329  -28.910 58.326  1.00 24.54  ? 29  ASP E CA  1 
ATOM   9357  C  C   . ASP E 1 29  ? 16.597  -28.794 59.829  1.00 23.92  ? 29  ASP E C   1 
ATOM   9358  O  O   . ASP E 1 29  ? 16.948  -27.718 60.305  1.00 25.27  ? 29  ASP E O   1 
ATOM   9359  C  CB  . ASP E 1 29  ? 17.455  -29.709 57.680  1.00 24.76  ? 29  ASP E CB  1 
ATOM   9360  C  CG  . ASP E 1 29  ? 17.306  -30.044 56.222  1.00 25.71  ? 29  ASP E CG  1 
ATOM   9361  O  OD1 . ASP E 1 29  ? 16.226  -29.692 55.649  1.00 25.32  ? 29  ASP E OD1 1 
ATOM   9362  O  OD2 . ASP E 1 29  ? 18.280  -30.657 55.720  1.00 28.50  ? 29  ASP E OD2 1 
ATOM   9363  N  N   . SER E 1 30  ? 16.519  -29.948 60.519  1.00 22.54  ? 30  SER E N   1 
ATOM   9364  C  CA  . SER E 1 30  ? 16.888  -30.048 61.916  1.00 24.96  ? 30  SER E CA  1 
ATOM   9365  C  C   . SER E 1 30  ? 18.298  -29.538 62.088  1.00 25.61  ? 30  SER E C   1 
ATOM   9366  O  O   . SER E 1 30  ? 19.189  -30.040 61.413  1.00 26.32  ? 30  SER E O   1 
ATOM   9367  C  CB  . SER E 1 30  ? 16.832  -31.460 62.427  1.00 26.84  ? 30  SER E CB  1 
ATOM   9368  O  OG  . SER E 1 30  ? 15.570  -32.018 62.108  1.00 32.22  ? 30  SER E OG  1 
ATOM   9369  N  N   . GLY E 1 31  ? 18.468  -28.574 62.993  1.00 25.19  ? 31  GLY E N   1 
ATOM   9370  C  CA  . GLY E 1 31  ? 19.793  -28.119 63.344  1.00 28.95  ? 31  GLY E CA  1 
ATOM   9371  C  C   . GLY E 1 31  ? 20.288  -27.027 62.413  1.00 31.14  ? 31  GLY E C   1 
ATOM   9372  O  O   . GLY E 1 31  ? 21.399  -26.541 62.590  1.00 35.58  ? 31  GLY E O   1 
ATOM   9373  N  N   . GLY E 1 32  ? 19.441  -26.644 61.453  1.00 27.44  ? 32  GLY E N   1 
ATOM   9374  C  CA  . GLY E 1 32  ? 19.895  -25.757 60.392  1.00 28.12  ? 32  GLY E CA  1 
ATOM   9375  C  C   . GLY E 1 32  ? 19.951  -24.283 60.812  1.00 26.80  ? 32  GLY E C   1 
ATOM   9376  O  O   . GLY E 1 32  ? 20.499  -23.461 60.069  1.00 31.33  ? 32  GLY E O   1 
ATOM   9377  N  N   . GLU E 1 33  ? 19.390  -23.945 61.982  1.00 23.63  ? 33  GLU E N   1 
ATOM   9378  C  CA  . GLU E 1 33  ? 19.062  -22.563 62.302  1.00 23.63  ? 33  GLU E CA  1 
ATOM   9379  C  C   . GLU E 1 33  ? 20.324  -21.681 62.320  1.00 29.76  ? 33  GLU E C   1 
ATOM   9380  O  O   . GLU E 1 33  ? 20.298  -20.494 61.982  1.00 26.62  ? 33  GLU E O   1 
ATOM   9381  C  CB  . GLU E 1 33  ? 18.341  -22.483 63.657  1.00 25.33  ? 33  GLU E CB  1 
ATOM   9382  C  CG  . GLU E 1 33  ? 16.979  -23.145 63.756  1.00 26.06  ? 33  GLU E CG  1 
ATOM   9383  C  CD  . GLU E 1 33  ? 16.945  -24.656 63.933  1.00 30.46  ? 33  GLU E CD  1 
ATOM   9384  O  OE1 . GLU E 1 33  ? 18.009  -25.346 64.060  1.00 27.74  ? 33  GLU E OE1 1 
ATOM   9385  O  OE2 . GLU E 1 33  ? 15.760  -25.123 63.909  1.00 27.91  ? 33  GLU E OE2 1 
ATOM   9386  N  N   . ASP E 1 34  ? 21.453  -22.230 62.779  1.00 33.58  ? 34  ASP E N   1 
ATOM   9387  C  CA  . ASP E 1 34  ? 22.651  -21.439 62.950  1.00 32.78  ? 34  ASP E CA  1 
ATOM   9388  C  C   . ASP E 1 34  ? 23.225  -21.079 61.589  1.00 29.07  ? 34  ASP E C   1 
ATOM   9389  O  O   . ASP E 1 34  ? 23.592  -19.928 61.348  1.00 30.19  ? 34  ASP E O   1 
ATOM   9390  C  CB  . ASP E 1 34  ? 23.676  -22.196 63.774  1.00 36.69  ? 34  ASP E CB  1 
ATOM   9391  C  CG  . ASP E 1 34  ? 23.451  -22.129 65.270  1.00 40.51  ? 34  ASP E CG  1 
ATOM   9392  O  OD1 . ASP E 1 34  ? 23.179  -21.011 65.752  1.00 38.92  ? 34  ASP E OD1 1 
ATOM   9393  O  OD2 . ASP E 1 34  ? 23.601  -23.172 65.924  1.00 45.70  ? 34  ASP E OD2 1 
ATOM   9394  N  N   . THR E 1 35  ? 23.327  -22.084 60.714  1.00 25.49  ? 35  THR E N   1 
ATOM   9395  C  CA  . THR E 1 35  ? 23.824  -21.829 59.379  1.00 25.26  ? 35  THR E CA  1 
ATOM   9396  C  C   . THR E 1 35  ? 22.990  -20.748 58.700  1.00 24.94  ? 35  THR E C   1 
ATOM   9397  O  O   . THR E 1 35  ? 23.530  -19.843 58.080  1.00 27.70  ? 35  THR E O   1 
ATOM   9398  C  CB  . THR E 1 35  ? 23.784  -23.113 58.581  1.00 26.96  ? 35  THR E CB  1 
ATOM   9399  O  OG1 . THR E 1 35  ? 24.768  -23.901 59.244  1.00 28.13  ? 35  THR E OG1 1 
ATOM   9400  C  CG2 . THR E 1 35  ? 24.204  -22.885 57.148  1.00 28.50  ? 35  THR E CG2 1 
ATOM   9401  N  N   . VAL E 1 36  ? 21.670  -20.865 58.834  1.00 24.38  ? 36  VAL E N   1 
ATOM   9402  C  CA  . VAL E 1 36  ? 20.740  -19.934 58.240  1.00 22.49  ? 36  VAL E CA  1 
ATOM   9403  C  C   . VAL E 1 36  ? 20.954  -18.548 58.807  1.00 22.16  ? 36  VAL E C   1 
ATOM   9404  O  O   . VAL E 1 36  ? 20.988  -17.610 58.054  1.00 26.18  ? 36  VAL E O   1 
ATOM   9405  C  CB  . VAL E 1 36  ? 19.285  -20.387 58.423  1.00 23.86  ? 36  VAL E CB  1 
ATOM   9406  C  CG1 . VAL E 1 36  ? 18.275  -19.318 58.030  1.00 25.16  ? 36  VAL E CG1 1 
ATOM   9407  C  CG2 . VAL E 1 36  ? 19.023  -21.640 57.595  1.00 24.53  ? 36  VAL E CG2 1 
ATOM   9408  N  N   . ARG E 1 37  ? 21.053  -18.395 60.102  1.00 24.79  ? 37  ARG E N   1 
ATOM   9409  C  CA  . ARG E 1 37  ? 21.255  -17.082 60.691  1.00 28.63  ? 37  ARG E CA  1 
ATOM   9410  C  C   . ARG E 1 37  ? 22.528  -16.424 60.178  1.00 27.96  ? 37  ARG E C   1 
ATOM   9411  O  O   . ARG E 1 37  ? 22.507  -15.221 59.972  1.00 27.93  ? 37  ARG E O   1 
ATOM   9412  C  CB  . ARG E 1 37  ? 21.340  -17.174 62.212  1.00 33.94  ? 37  ARG E CB  1 
ATOM   9413  C  CG  . ARG E 1 37  ? 20.091  -16.698 62.932  1.00 42.81  ? 37  ARG E CG  1 
ATOM   9414  C  CD  . ARG E 1 37  ? 20.383  -16.484 64.422  1.00 49.98  ? 37  ARG E CD  1 
ATOM   9415  N  NE  . ARG E 1 37  ? 20.688  -17.822 64.927  1.00 60.38  ? 37  ARG E NE  1 
ATOM   9416  C  CZ  . ARG E 1 37  ? 19.790  -18.767 65.205  1.00 62.67  ? 37  ARG E CZ  1 
ATOM   9417  N  NH1 . ARG E 1 37  ? 18.541  -18.454 65.510  1.00 58.51  ? 37  ARG E NH1 1 
ATOM   9418  N  NH2 . ARG E 1 37  ? 20.176  -20.028 65.276  1.00 58.94  ? 37  ARG E NH2 1 
ATOM   9419  N  N   . ASP E 1 38  ? 23.613  -17.183 59.971  1.00 29.53  ? 38  ASP E N   1 
ATOM   9420  C  CA  . ASP E 1 38  ? 24.821  -16.591 59.420  1.00 35.64  ? 38  ASP E CA  1 
ATOM   9421  C  C   . ASP E 1 38  ? 24.594  -16.038 58.015  1.00 32.64  ? 38  ASP E C   1 
ATOM   9422  O  O   . ASP E 1 38  ? 25.039  -14.941 57.686  1.00 29.85  ? 38  ASP E O   1 
ATOM   9423  C  CB  . ASP E 1 38  ? 25.976  -17.564 59.257  1.00 41.02  ? 38  ASP E CB  1 
ATOM   9424  C  CG  . ASP E 1 38  ? 26.800  -17.773 60.513  1.00 53.99  ? 38  ASP E CG  1 
ATOM   9425  O  OD1 . ASP E 1 38  ? 27.064  -16.765 61.212  1.00 64.16  ? 38  ASP E OD1 1 
ATOM   9426  O  OD2 . ASP E 1 38  ? 27.174  -18.939 60.781  1.00 65.03  ? 38  ASP E OD2 1 
ATOM   9427  N  N   . LEU E 1 39  ? 23.957  -16.852 57.174  1.00 28.75  ? 39  LEU E N   1 
ATOM   9428  C  CA  . LEU E 1 39  ? 23.689  -16.477 55.798  1.00 26.70  ? 39  LEU E CA  1 
ATOM   9429  C  C   . LEU E 1 39  ? 22.820  -15.215 55.771  1.00 27.81  ? 39  LEU E C   1 
ATOM   9430  O  O   . LEU E 1 39  ? 23.066  -14.313 54.967  1.00 27.58  ? 39  LEU E O   1 
ATOM   9431  C  CB  . LEU E 1 39  ? 23.057  -17.679 55.104  1.00 27.85  ? 39  LEU E CB  1 
ATOM   9432  C  CG  . LEU E 1 39  ? 22.608  -17.551 53.640  1.00 32.01  ? 39  LEU E CG  1 
ATOM   9433  C  CD1 . LEU E 1 39  ? 21.343  -16.764 53.409  1.00 31.22  ? 39  LEU E CD1 1 
ATOM   9434  C  CD2 . LEU E 1 39  ? 23.687  -16.922 52.820  1.00 34.82  ? 39  LEU E CD2 1 
ATOM   9435  N  N   . LEU E 1 40  ? 21.815  -15.117 56.653  1.00 28.11  ? 40  LEU E N   1 
ATOM   9436  C  CA  . LEU E 1 40  ? 20.911  -13.993 56.566  1.00 28.74  ? 40  LEU E CA  1 
ATOM   9437  C  C   . LEU E 1 40  ? 21.656  -12.700 56.837  1.00 28.42  ? 40  LEU E C   1 
ATOM   9438  O  O   . LEU E 1 40  ? 21.286  -11.647 56.325  1.00 28.18  ? 40  LEU E O   1 
ATOM   9439  C  CB  . LEU E 1 40  ? 19.737  -14.138 57.528  1.00 32.33  ? 40  LEU E CB  1 
ATOM   9440  C  CG  . LEU E 1 40  ? 18.748  -15.255 57.208  1.00 33.96  ? 40  LEU E CG  1 
ATOM   9441  C  CD1 . LEU E 1 40  ? 17.707  -15.278 58.312  1.00 39.65  ? 40  LEU E CD1 1 
ATOM   9442  C  CD2 . LEU E 1 40  ? 18.110  -15.030 55.867  1.00 31.55  ? 40  LEU E CD2 1 
ATOM   9443  N  N   . SER E 1 41  ? 22.672  -12.768 57.688  1.00 30.04  ? 41  SER E N   1 
ATOM   9444  C  CA  . SER E 1 41  ? 23.398  -11.557 58.039  1.00 40.96  ? 41  SER E CA  1 
ATOM   9445  C  C   . SER E 1 41  ? 24.356  -11.151 56.912  1.00 36.87  ? 41  SER E C   1 
ATOM   9446  O  O   . SER E 1 41  ? 24.874  -10.055 56.912  1.00 31.59  ? 41  SER E O   1 
ATOM   9447  C  CB  . SER E 1 41  ? 24.129  -11.718 59.353  1.00 44.36  ? 41  SER E CB  1 
ATOM   9448  O  OG  . SER E 1 41  ? 25.187  -12.665 59.214  1.00 50.78  ? 41  SER E OG  1 
ATOM   9449  N  N   . ASP E 1 42  ? 24.595  -12.026 55.935  1.00 34.28  ? 42  ASP E N   1 
ATOM   9450  C  CA  . ASP E 1 42  ? 25.563  -11.725 54.899  1.00 30.65  ? 42  ASP E CA  1 
ATOM   9451  C  C   . ASP E 1 42  ? 24.900  -11.550 53.528  1.00 34.02  ? 42  ASP E C   1 
ATOM   9452  O  O   . ASP E 1 42  ? 25.573  -11.299 52.529  1.00 27.38  ? 42  ASP E O   1 
ATOM   9453  C  CB  . ASP E 1 42  ? 26.547  -12.868 54.794  1.00 29.77  ? 42  ASP E CB  1 
ATOM   9454  C  CG  . ASP E 1 42  ? 27.631  -12.978 55.849  1.00 33.64  ? 42  ASP E CG  1 
ATOM   9455  O  OD1 . ASP E 1 42  ? 27.947  -12.025 56.589  1.00 39.17  ? 42  ASP E OD1 1 
ATOM   9456  O  OD2 . ASP E 1 42  ? 28.136  -14.080 55.942  1.00 37.53  ? 42  ASP E OD2 1 
ATOM   9457  N  N   . VAL E 1 43  ? 23.575  -11.747 53.434  1.00 36.33  ? 43  VAL E N   1 
ATOM   9458  C  CA  . VAL E 1 43  ? 22.960  -11.873 52.127  1.00 31.23  ? 43  VAL E CA  1 
ATOM   9459  C  C   . VAL E 1 43  ? 23.046  -10.528 51.396  1.00 28.92  ? 43  VAL E C   1 
ATOM   9460  O  O   . VAL E 1 43  ? 23.294  -10.522 50.194  1.00 22.13  ? 43  VAL E O   1 
ATOM   9461  C  CB  . VAL E 1 43  ? 21.524  -12.418 52.241  1.00 31.52  ? 43  VAL E CB  1 
ATOM   9462  C  CG1 . VAL E 1 43  ? 20.585  -11.372 52.811  1.00 33.07  ? 43  VAL E CG1 1 
ATOM   9463  C  CG2 . VAL E 1 43  ? 20.989  -12.887 50.918  1.00 31.66  ? 43  VAL E CG2 1 
ATOM   9464  N  N   . ALA E 1 44  ? 22.945  -9.382  52.098  1.00 27.41  ? 44  ALA E N   1 
ATOM   9465  C  CA  . ALA E 1 44  ? 23.109  -8.098  51.415  1.00 26.64  ? 44  ALA E CA  1 
ATOM   9466  C  C   . ALA E 1 44  ? 24.501  -7.959  50.803  1.00 29.25  ? 44  ALA E C   1 
ATOM   9467  O  O   . ALA E 1 44  ? 24.620  -7.407  49.711  1.00 26.99  ? 44  ALA E O   1 
ATOM   9468  C  CB  . ALA E 1 44  ? 22.839  -6.938  52.300  1.00 25.07  ? 44  ALA E CB  1 
ATOM   9469  N  N   . SER E 1 45  ? 25.551  -8.466  51.467  1.00 31.77  ? 45  SER E N   1 
ATOM   9470  C  CA  . SER E 1 45  ? 26.893  -8.245  50.933  1.00 32.13  ? 45  SER E CA  1 
ATOM   9471  C  C   . SER E 1 45  ? 27.197  -9.242  49.828  1.00 31.29  ? 45  SER E C   1 
ATOM   9472  O  O   . SER E 1 45  ? 27.950  -8.885  48.918  1.00 33.60  ? 45  SER E O   1 
ATOM   9473  C  CB  . SER E 1 45  ? 27.981  -8.187  51.965  1.00 34.44  ? 45  SER E CB  1 
ATOM   9474  O  OG  . SER E 1 45  ? 27.864  -9.314  52.800  1.00 43.48  ? 45  SER E OG  1 
ATOM   9475  N  N   . LEU E 1 46  ? 26.548  -10.417 49.835  1.00 29.81  ? 46  LEU E N   1 
ATOM   9476  C  CA  . LEU E 1 46  ? 26.599  -11.297 48.662  1.00 30.65  ? 46  LEU E CA  1 
ATOM   9477  C  C   . LEU E 1 46  ? 25.914  -10.656 47.443  1.00 29.93  ? 46  LEU E C   1 
ATOM   9478  O  O   . LEU E 1 46  ? 26.393  -10.765 46.322  1.00 32.08  ? 46  LEU E O   1 
ATOM   9479  C  CB  . LEU E 1 46  ? 25.971  -12.644 49.013  1.00 31.42  ? 46  LEU E CB  1 
ATOM   9480  C  CG  . LEU E 1 46  ? 26.745  -13.458 50.043  1.00 32.81  ? 46  LEU E CG  1 
ATOM   9481  C  CD1 . LEU E 1 46  ? 25.974  -14.705 50.365  1.00 37.84  ? 46  LEU E CD1 1 
ATOM   9482  C  CD2 . LEU E 1 46  ? 28.107  -13.822 49.486  1.00 32.89  ? 46  LEU E CD2 1 
ATOM   9483  N  N   . GLU E 1 47  ? 24.800  -9.965  47.678  1.00 30.48  ? 47  GLU E N   1 
ATOM   9484  C  CA  . GLU E 1 47  ? 24.124  -9.250  46.622  1.00 32.37  ? 47  GLU E CA  1 
ATOM   9485  C  C   . GLU E 1 47  ? 25.090  -8.248  45.991  1.00 29.99  ? 47  GLU E C   1 
ATOM   9486  O  O   . GLU E 1 47  ? 25.251  -8.234  44.781  1.00 28.29  ? 47  GLU E O   1 
ATOM   9487  C  CB  . GLU E 1 47  ? 22.858  -8.629  47.209  1.00 34.22  ? 47  GLU E CB  1 
ATOM   9488  C  CG  . GLU E 1 47  ? 21.977  -7.989  46.145  1.00 36.11  ? 47  GLU E CG  1 
ATOM   9489  C  CD  . GLU E 1 47  ? 20.922  -7.176  46.850  1.00 43.96  ? 47  GLU E CD  1 
ATOM   9490  O  OE1 . GLU E 1 47  ? 21.432  -6.256  47.516  1.00 57.28  ? 47  GLU E OE1 1 
ATOM   9491  O  OE2 . GLU E 1 47  ? 19.695  -7.441  46.808  1.00 53.00  ? 47  GLU E OE2 1 
ATOM   9492  N  N   . ARG E 1 48  ? 25.807  -7.461  46.797  1.00 30.76  ? 48  ARG E N   1 
ATOM   9493  C  CA  . ARG E 1 48  ? 26.776  -6.511  46.252  1.00 31.39  ? 48  ARG E CA  1 
ATOM   9494  C  C   . ARG E 1 48  ? 27.968  -7.198  45.577  1.00 29.10  ? 48  ARG E C   1 
ATOM   9495  O  O   . ARG E 1 48  ? 28.400  -6.764  44.527  1.00 30.52  ? 48  ARG E O   1 
ATOM   9496  C  CB  . ARG E 1 48  ? 27.327  -5.564  47.313  1.00 32.16  ? 48  ARG E CB  1 
ATOM   9497  C  CG  . ARG E 1 48  ? 26.186  -4.682  47.761  1.00 37.79  ? 48  ARG E CG  1 
ATOM   9498  C  CD  . ARG E 1 48  ? 26.729  -3.507  48.516  1.00 49.62  ? 48  ARG E CD  1 
ATOM   9499  N  NE  . ARG E 1 48  ? 27.404  -3.927  49.755  1.00 53.20  ? 48  ARG E NE  1 
ATOM   9500  C  CZ  . ARG E 1 48  ? 26.816  -4.290  50.890  1.00 49.22  ? 48  ARG E CZ  1 
ATOM   9501  N  NH1 . ARG E 1 48  ? 25.497  -4.275  51.024  1.00 42.92  ? 48  ARG E NH1 1 
ATOM   9502  N  NH2 . ARG E 1 48  ? 27.569  -4.665  51.909  1.00 54.49  ? 48  ARG E NH2 1 
ATOM   9503  N  N   . ALA E 1 49  ? 28.510  -8.261  46.156  1.00 25.64  ? 49  ALA E N   1 
ATOM   9504  C  CA  . ALA E 1 49  ? 29.640  -8.948  45.561  1.00 26.23  ? 49  ALA E CA  1 
ATOM   9505  C  C   . ALA E 1 49  ? 29.368  -9.366  44.128  1.00 26.49  ? 49  ALA E C   1 
ATOM   9506  O  O   . ALA E 1 49  ? 30.196  -9.169  43.239  1.00 34.47  ? 49  ALA E O   1 
ATOM   9507  C  CB  . ALA E 1 49  ? 29.986  -10.176 46.374  1.00 26.06  ? 49  ALA E CB  1 
ATOM   9508  N  N   . VAL E 1 50  ? 28.216  -10.008 43.956  1.00 27.20  ? 50  VAL E N   1 
ATOM   9509  C  CA  . VAL E 1 50  ? 27.830  -10.578 42.680  1.00 30.28  ? 50  VAL E CA  1 
ATOM   9510  C  C   . VAL E 1 50  ? 27.414  -9.458  41.709  1.00 29.85  ? 50  VAL E C   1 
ATOM   9511  O  O   . VAL E 1 50  ? 27.678  -9.486  40.503  1.00 31.70  ? 50  VAL E O   1 
ATOM   9512  C  CB  . VAL E 1 50  ? 26.721  -11.642 42.822  1.00 28.79  ? 50  VAL E CB  1 
ATOM   9513  C  CG1 . VAL E 1 50  ? 26.265  -12.115 41.437  1.00 31.57  ? 50  VAL E CG1 1 
ATOM   9514  C  CG2 . VAL E 1 50  ? 27.157  -12.829 43.689  1.00 24.07  ? 50  VAL E CG2 1 
ATOM   9515  N  N   . GLY E 1 51  ? 26.754  -8.447  42.229  1.00 27.71  ? 51  GLY E N   1 
ATOM   9516  C  CA  . GLY E 1 51  ? 26.097  -7.498  41.354  1.00 28.62  ? 51  GLY E CA  1 
ATOM   9517  C  C   . GLY E 1 51  ? 26.956  -6.292  40.999  1.00 29.05  ? 51  GLY E C   1 
ATOM   9518  O  O   . GLY E 1 51  ? 26.791  -5.729  39.926  1.00 30.84  ? 51  GLY E O   1 
ATOM   9519  N  N   . PHE E 1 52  ? 27.799  -5.823  41.918  1.00 29.28  ? 52  PHE E N   1 
ATOM   9520  C  CA  . PHE E 1 52  ? 28.392  -4.501  41.774  1.00 28.43  ? 52  PHE E CA  1 
ATOM   9521  C  C   . PHE E 1 52  ? 29.219  -4.450  40.493  1.00 31.29  ? 52  PHE E C   1 
ATOM   9522  O  O   . PHE E 1 52  ? 29.148  -3.474  39.765  1.00 34.44  ? 52  PHE E O   1 
ATOM   9523  C  CB  . PHE E 1 52  ? 29.256  -4.125  42.977  1.00 29.68  ? 52  PHE E CB  1 
ATOM   9524  C  CG  . PHE E 1 52  ? 29.966  -2.822  42.693  1.00 31.90  ? 52  PHE E CG  1 
ATOM   9525  C  CD1 . PHE E 1 52  ? 29.287  -1.622  42.778  1.00 32.66  ? 52  PHE E CD1 1 
ATOM   9526  C  CD2 . PHE E 1 52  ? 31.280  -2.813  42.255  1.00 34.10  ? 52  PHE E CD2 1 
ATOM   9527  C  CE1 . PHE E 1 52  ? 29.905  -0.451  42.413  1.00 34.60  ? 52  PHE E CE1 1 
ATOM   9528  C  CE2 . PHE E 1 52  ? 31.912  -1.626  41.949  1.00 35.40  ? 52  PHE E CE2 1 
ATOM   9529  C  CZ  . PHE E 1 52  ? 31.211  -0.453  42.017  1.00 32.59  ? 52  PHE E CZ  1 
ATOM   9530  N  N   . ARG E 1 53  ? 29.963  -5.519  40.186  1.00 38.36  ? 53  ARG E N   1 
ATOM   9531  C  CA  . ARG E 1 53  ? 30.852  -5.504  39.038  1.00 39.61  ? 53  ARG E CA  1 
ATOM   9532  C  C   . ARG E 1 53  ? 30.067  -5.493  37.713  1.00 39.21  ? 53  ARG E C   1 
ATOM   9533  O  O   . ARG E 1 53  ? 30.678  -5.272  36.666  1.00 41.97  ? 53  ARG E O   1 
ATOM   9534  C  CB  . ARG E 1 53  ? 31.855  -6.662  39.186  1.00 42.52  ? 53  ARG E CB  1 
ATOM   9535  C  CG  . ARG E 1 53  ? 31.424  -8.040  38.711  1.00 51.12  ? 53  ARG E CG  1 
ATOM   9536  C  CD  . ARG E 1 53  ? 32.614  -8.959  38.331  1.00 52.35  ? 53  ARG E CD  1 
ATOM   9537  N  NE  . ARG E 1 53  ? 32.298  -10.361 38.628  1.00 52.32  ? 53  ARG E NE  1 
ATOM   9538  C  CZ  . ARG E 1 53  ? 31.897  -10.702 39.837  1.00 55.77  ? 53  ARG E CZ  1 
ATOM   9539  N  NH1 . ARG E 1 53  ? 31.702  -9.782  40.784  1.00 67.23  ? 53  ARG E NH1 1 
ATOM   9540  N  NH2 . ARG E 1 53  ? 31.664  -11.967 40.098  1.00 56.03  ? 53  ARG E NH2 1 
ATOM   9541  N  N   . ALA E 1 54  ? 28.746  -5.747  37.739  1.00 34.33  ? 54  ALA E N   1 
ATOM   9542  C  CA  . ALA E 1 54  ? 27.906  -5.762  36.543  1.00 36.44  ? 54  ALA E CA  1 
ATOM   9543  C  C   . ALA E 1 54  ? 27.039  -4.508  36.416  1.00 38.89  ? 54  ALA E C   1 
ATOM   9544  O  O   . ALA E 1 54  ? 26.084  -4.512  35.634  1.00 38.24  ? 54  ALA E O   1 
ATOM   9545  C  CB  . ALA E 1 54  ? 27.016  -7.000  36.540  1.00 36.62  ? 54  ALA E CB  1 
ATOM   9546  N  N   . GLN E 1 55  ? 27.360  -3.450  37.184  1.00 49.33  ? 55  GLN E N   1 
ATOM   9547  C  CA  . GLN E 1 55  ? 26.669  -2.174  37.088  1.00 61.36  ? 55  GLN E CA  1 
ATOM   9548  C  C   . GLN E 1 55  ? 26.928  -1.525  35.725  1.00 66.68  ? 55  GLN E C   1 
ATOM   9549  O  O   . GLN E 1 55  ? 27.952  -1.785  35.092  1.00 65.79  ? 55  GLN E O   1 
ATOM   9550  C  CB  . GLN E 1 55  ? 27.058  -1.130  38.147  1.00 68.58  ? 55  GLN E CB  1 
ATOM   9551  C  CG  . GLN E 1 55  ? 26.424  -1.300  39.531  1.00 69.81  ? 55  GLN E CG  1 
ATOM   9552  C  CD  . GLN E 1 55  ? 24.957  -1.696  39.543  1.00 81.83  ? 55  GLN E CD  1 
ATOM   9553  O  OE1 . GLN E 1 55  ? 24.389  -2.250  38.587  1.00 104.39 ? 55  GLN E OE1 1 
ATOM   9554  N  NE2 . GLN E 1 55  ? 24.307  -1.422  40.666  1.00 75.01  ? 55  GLN E NE2 1 
ATOM   9555  N  N   . PRO E 1 56  ? 25.991  -0.676  35.234  1.00 74.58  ? 56  PRO E N   1 
ATOM   9556  C  CA  . PRO E 1 56  ? 24.661  -0.524  35.833  1.00 69.95  ? 56  PRO E CA  1 
ATOM   9557  C  C   . PRO E 1 56  ? 23.532  -1.281  35.116  1.00 62.61  ? 56  PRO E C   1 
ATOM   9558  O  O   . PRO E 1 56  ? 22.400  -1.257  35.590  1.00 64.91  ? 56  PRO E O   1 
ATOM   9559  C  CB  . PRO E 1 56  ? 24.490  1.018   35.818  1.00 67.31  ? 56  PRO E CB  1 
ATOM   9560  C  CG  . PRO E 1 56  ? 25.412  1.491   34.694  1.00 70.65  ? 56  PRO E CG  1 
ATOM   9561  C  CD  . PRO E 1 56  ? 26.181  0.279   34.139  1.00 73.25  ? 56  PRO E CD  1 
ATOM   9562  N  N   . ASP E 1 57  ? 23.834  -2.012  34.032  1.00 61.92  ? 57  ASP E N   1 
ATOM   9563  C  CA  . ASP E 1 57  ? 22.787  -2.815  33.391  1.00 64.52  ? 57  ASP E CA  1 
ATOM   9564  C  C   . ASP E 1 57  ? 22.339  -4.012  34.251  1.00 51.05  ? 57  ASP E C   1 
ATOM   9565  O  O   . ASP E 1 57  ? 21.314  -4.597  33.930  1.00 36.46  ? 57  ASP E O   1 
ATOM   9566  C  CB  . ASP E 1 57  ? 23.182  -3.518  32.098  1.00 67.93  ? 57  ASP E CB  1 
ATOM   9567  C  CG  . ASP E 1 57  ? 24.323  -2.946  31.276  1.00 75.83  ? 57  ASP E CG  1 
ATOM   9568  O  OD1 . ASP E 1 57  ? 24.074  -1.934  30.612  1.00 79.71  ? 57  ASP E OD1 1 
ATOM   9569  O  OD2 . ASP E 1 57  ? 25.426  -3.552  31.292  1.00 74.71  ? 57  ASP E OD2 1 
ATOM   9570  N  N   . GLY E 1 58  ? 23.096  -4.420  35.287  1.00 44.40  ? 58  GLY E N   1 
ATOM   9571  C  CA  . GLY E 1 58  ? 22.825  -5.678  35.963  1.00 41.68  ? 58  GLY E CA  1 
ATOM   9572  C  C   . GLY E 1 58  ? 21.491  -5.692  36.721  1.00 35.33  ? 58  GLY E C   1 
ATOM   9573  O  O   . GLY E 1 58  ? 20.673  -6.605  36.572  1.00 32.29  ? 58  GLY E O   1 
ATOM   9574  N  N   . ARG E 1 59  ? 21.321  -4.701  37.598  1.00 33.43  ? 59  ARG E N   1 
ATOM   9575  C  CA  . ARG E 1 59  ? 20.060  -4.519  38.301  1.00 35.71  ? 59  ARG E CA  1 
ATOM   9576  C  C   . ARG E 1 59  ? 19.714  -5.744  39.144  1.00 31.94  ? 59  ARG E C   1 
ATOM   9577  O  O   . ARG E 1 59  ? 18.547  -6.081  39.312  1.00 31.40  ? 59  ARG E O   1 
ATOM   9578  C  CB  . ARG E 1 59  ? 18.937  -4.204  37.296  1.00 43.86  ? 59  ARG E CB  1 
ATOM   9579  C  CG  . ARG E 1 59  ? 19.091  -2.804  36.713  1.00 53.76  ? 59  ARG E CG  1 
ATOM   9580  C  CD  . ARG E 1 59  ? 17.787  -2.306  36.101  1.00 62.88  ? 59  ARG E CD  1 
ATOM   9581  N  NE  . ARG E 1 59  ? 18.157  -1.588  34.880  1.00 77.03  ? 59  ARG E NE  1 
ATOM   9582  C  CZ  . ARG E 1 59  ? 18.555  -2.180  33.735  1.00 85.33  ? 59  ARG E CZ  1 
ATOM   9583  N  NH1 . ARG E 1 59  ? 18.282  -3.447  33.447  1.00 88.54  ? 59  ARG E NH1 1 
ATOM   9584  N  NH2 . ARG E 1 59  ? 19.176  -1.461  32.826  1.00 79.29  ? 59  ARG E NH2 1 
ATOM   9585  N  N   . LEU E 1 60  ? 20.740  -6.404  39.685  1.00 29.40  ? 60  LEU E N   1 
ATOM   9586  C  CA  . LEU E 1 60  ? 20.572  -7.592  40.506  1.00 27.21  ? 60  LEU E CA  1 
ATOM   9587  C  C   . LEU E 1 60  ? 20.076  -7.201  41.885  1.00 29.91  ? 60  LEU E C   1 
ATOM   9588  O  O   . LEU E 1 60  ? 20.639  -6.313  42.468  1.00 33.96  ? 60  LEU E O   1 
ATOM   9589  C  CB  . LEU E 1 60  ? 21.894  -8.308  40.624  1.00 27.84  ? 60  LEU E CB  1 
ATOM   9590  C  CG  . LEU E 1 60  ? 21.882  -9.528  41.546  1.00 36.17  ? 60  LEU E CG  1 
ATOM   9591  C  CD1 . LEU E 1 60  ? 21.098  -10.683 40.948  1.00 33.98  ? 60  LEU E CD1 1 
ATOM   9592  C  CD2 . LEU E 1 60  ? 23.313  -9.933  41.875  1.00 38.35  ? 60  LEU E CD2 1 
ATOM   9593  N  N   . SER E 1 61  ? 19.037  -7.865  42.394  1.00 30.32  ? 61  SER E N   1 
ATOM   9594  C  CA  . SER E 1 61  ? 18.511  -7.645  43.728  1.00 28.06  ? 61  SER E CA  1 
ATOM   9595  C  C   . SER E 1 61  ? 18.092  -9.007  44.277  1.00 29.39  ? 61  SER E C   1 
ATOM   9596  O  O   . SER E 1 61  ? 17.759  -9.897  43.525  1.00 29.76  ? 61  SER E O   1 
ATOM   9597  C  CB  . SER E 1 61  ? 17.358  -6.664  43.729  1.00 27.40  ? 61  SER E CB  1 
ATOM   9598  O  OG  . SER E 1 61  ? 16.124  -7.312  43.460  1.00 33.81  ? 61  SER E OG  1 
ATOM   9599  N  N   . CYS E 1 62  ? 18.090  -9.174  45.590  1.00 28.08  ? 62  CYS E N   1 
ATOM   9600  C  CA  . CYS E 1 62  ? 17.595  -10.381 46.220  1.00 25.94  ? 62  CYS E CA  1 
ATOM   9601  C  C   . CYS E 1 62  ? 16.667  -9.947  47.329  1.00 24.02  ? 62  CYS E C   1 
ATOM   9602  O  O   . CYS E 1 62  ? 17.038  -9.109  48.117  1.00 26.31  ? 62  CYS E O   1 
ATOM   9603  C  CB  . CYS E 1 62  ? 18.720  -11.205 46.829  1.00 25.39  ? 62  CYS E CB  1 
ATOM   9604  S  SG  . CYS E 1 62  ? 18.115  -12.696 47.663  1.00 28.37  ? 62  CYS E SG  1 
ATOM   9605  N  N   . VAL E 1 63  ? 15.438  -10.423 47.366  1.00 24.81  ? 63  VAL E N   1 
ATOM   9606  C  CA  . VAL E 1 63  ? 14.623  -10.183 48.550  1.00 25.99  ? 63  VAL E CA  1 
ATOM   9607  C  C   . VAL E 1 63  ? 14.443  -11.498 49.303  1.00 24.77  ? 63  VAL E C   1 
ATOM   9608  O  O   . VAL E 1 63  ? 14.109  -12.516 48.710  1.00 23.43  ? 63  VAL E O   1 
ATOM   9609  C  CB  . VAL E 1 63  ? 13.289  -9.550  48.167  1.00 26.27  ? 63  VAL E CB  1 
ATOM   9610  C  CG1 . VAL E 1 63  ? 12.392  -9.404  49.375  1.00 28.39  ? 63  VAL E CG1 1 
ATOM   9611  C  CG2 . VAL E 1 63  ? 13.527  -8.194  47.525  1.00 28.72  ? 63  VAL E CG2 1 
ATOM   9612  N  N   . THR E 1 64  ? 14.704  -11.452 50.608  1.00 25.10  ? 64  THR E N   1 
ATOM   9613  C  CA  . THR E 1 64  ? 14.691  -12.629 51.453  1.00 25.80  ? 64  THR E CA  1 
ATOM   9614  C  C   . THR E 1 64  ? 13.467  -12.545 52.357  1.00 27.30  ? 64  THR E C   1 
ATOM   9615  O  O   . THR E 1 64  ? 13.243  -11.545 53.038  1.00 27.07  ? 64  THR E O   1 
ATOM   9616  C  CB  . THR E 1 64  ? 15.953  -12.655 52.301  1.00 29.39  ? 64  THR E CB  1 
ATOM   9617  O  OG1 . THR E 1 64  ? 17.043  -12.680 51.403  1.00 31.50  ? 64  THR E OG1 1 
ATOM   9618  C  CG2 . THR E 1 64  ? 16.040  -13.898 53.158  1.00 28.98  ? 64  THR E CG2 1 
ATOM   9619  N  N   . GLY E 1 65  ? 12.703  -13.629 52.384  1.00 26.06  ? 65  GLY E N   1 
ATOM   9620  C  CA  . GLY E 1 65  ? 11.548  -13.723 53.236  1.00 26.72  ? 65  GLY E CA  1 
ATOM   9621  C  C   . GLY E 1 65  ? 11.597  -14.969 54.124  1.00 27.98  ? 65  GLY E C   1 
ATOM   9622  O  O   . GLY E 1 65  ? 12.202  -16.001 53.808  1.00 26.08  ? 65  GLY E O   1 
ATOM   9623  N  N   . ILE E 1 66  ? 10.884  -14.856 55.236  1.00 28.95  ? 66  ILE E N   1 
ATOM   9624  C  CA  . ILE E 1 66  ? 10.889  -15.859 56.286  1.00 31.21  ? 66  ILE E CA  1 
ATOM   9625  C  C   . ILE E 1 66  ? 9.437   -16.183 56.638  1.00 29.98  ? 66  ILE E C   1 
ATOM   9626  O  O   . ILE E 1 66  ? 8.621   -15.285 56.802  1.00 26.52  ? 66  ILE E O   1 
ATOM   9627  C  CB  . ILE E 1 66  ? 11.661  -15.307 57.496  1.00 33.16  ? 66  ILE E CB  1 
ATOM   9628  C  CG1 . ILE E 1 66  ? 13.084  -14.922 57.103  1.00 36.04  ? 66  ILE E CG1 1 
ATOM   9629  C  CG2 . ILE E 1 66  ? 11.664  -16.318 58.632  1.00 35.54  ? 66  ILE E CG2 1 
ATOM   9630  C  CD1 . ILE E 1 66  ? 13.625  -13.792 57.925  1.00 38.80  ? 66  ILE E CD1 1 
ATOM   9631  N  N   . GLY E 1 67  ? 9.125   -17.477 56.736  1.00 28.61  ? 67  GLY E N   1 
ATOM   9632  C  CA  . GLY E 1 67  ? 7.784   -17.913 57.069  1.00 24.73  ? 67  GLY E CA  1 
ATOM   9633  C  C   . GLY E 1 67  ? 7.523   -17.859 58.573  1.00 24.76  ? 67  GLY E C   1 
ATOM   9634  O  O   . GLY E 1 67  ? 8.403   -17.613 59.385  1.00 24.73  ? 67  GLY E O   1 
ATOM   9635  N  N   . SER E 1 68  ? 6.278   -18.151 58.913  1.00 24.98  ? 68  SER E N   1 
ATOM   9636  C  CA  . SER E 1 68  ? 5.736   -18.078 60.259  1.00 26.82  ? 68  SER E CA  1 
ATOM   9637  C  C   . SER E 1 68  ? 6.428   -19.050 61.218  1.00 23.67  ? 68  SER E C   1 
ATOM   9638  O  O   . SER E 1 68  ? 6.947   -18.634 62.236  1.00 25.03  ? 68  SER E O   1 
ATOM   9639  C  CB  . SER E 1 68  ? 4.253   -18.365 60.154  1.00 30.68  ? 68  SER E CB  1 
ATOM   9640  O  OG  . SER E 1 68  ? 3.631   -17.978 61.348  1.00 30.01  ? 68  SER E OG  1 
ATOM   9641  N  N   . GLU E 1 69  ? 6.450   -20.336 60.892  1.00 24.72  ? 69  GLU E N   1 
ATOM   9642  C  CA  . GLU E 1 69  ? 7.086   -21.339 61.735  1.00 27.23  ? 69  GLU E CA  1 
ATOM   9643  C  C   . GLU E 1 69  ? 8.601   -21.165 61.821  1.00 28.39  ? 69  GLU E C   1 
ATOM   9644  O  O   . GLU E 1 69  ? 9.202   -21.444 62.873  1.00 28.28  ? 69  GLU E O   1 
ATOM   9645  C  CB  . GLU E 1 69  ? 6.821   -22.755 61.241  1.00 28.94  ? 69  GLU E CB  1 
ATOM   9646  C  CG  . GLU E 1 69  ? 5.353   -23.127 61.434  1.00 31.93  ? 69  GLU E CG  1 
ATOM   9647  C  CD  . GLU E 1 69  ? 5.015   -23.363 62.880  1.00 36.20  ? 69  GLU E CD  1 
ATOM   9648  O  OE1 . GLU E 1 69  ? 5.755   -24.123 63.552  1.00 38.29  ? 69  GLU E OE1 1 
ATOM   9649  O  OE2 . GLU E 1 69  ? 4.013   -22.783 63.313  1.00 44.46  ? 69  GLU E OE2 1 
ATOM   9650  N  N   . ALA E 1 70  ? 9.222   -20.780 60.701  1.00 23.79  ? 70  ALA E N   1 
ATOM   9651  C  CA  . ALA E 1 70  ? 10.648  -20.538 60.699  1.00 23.59  ? 70  ALA E CA  1 
ATOM   9652  C  C   . ALA E 1 70  ? 10.971  -19.319 61.565  1.00 26.28  ? 70  ALA E C   1 
ATOM   9653  O  O   . ALA E 1 70  ? 12.015  -19.268 62.232  1.00 28.37  ? 70  ALA E O   1 
ATOM   9654  C  CB  . ALA E 1 70  ? 11.144  -20.362 59.304  1.00 25.30  ? 70  ALA E CB  1 
ATOM   9655  N  N   . TRP E 1 71  ? 10.089  -18.326 61.551  1.00 24.90  ? 71  TRP E N   1 
ATOM   9656  C  CA  . TRP E 1 71  ? 10.354  -17.125 62.320  1.00 28.10  ? 71  TRP E CA  1 
ATOM   9657  C  C   . TRP E 1 71  ? 10.621  -17.456 63.794  1.00 30.28  ? 71  TRP E C   1 
ATOM   9658  O  O   . TRP E 1 71  ? 11.524  -16.916 64.411  1.00 31.17  ? 71  TRP E O   1 
ATOM   9659  C  CB  . TRP E 1 71  ? 9.180   -16.143 62.185  1.00 29.22  ? 71  TRP E CB  1 
ATOM   9660  C  CG  . TRP E 1 71  ? 9.518   -14.874 62.887  1.00 31.06  ? 71  TRP E CG  1 
ATOM   9661  C  CD1 . TRP E 1 71  ? 9.496   -14.640 64.226  1.00 30.64  ? 71  TRP E CD1 1 
ATOM   9662  C  CD2 . TRP E 1 71  ? 10.105  -13.715 62.265  1.00 33.20  ? 71  TRP E CD2 1 
ATOM   9663  N  NE1 . TRP E 1 71  ? 9.955   -13.376 64.466  1.00 31.67  ? 71  TRP E NE1 1 
ATOM   9664  C  CE2 . TRP E 1 71  ? 10.362  -12.797 63.301  1.00 30.58  ? 71  TRP E CE2 1 
ATOM   9665  C  CE3 . TRP E 1 71  ? 10.418  -13.370 60.948  1.00 29.14  ? 71  TRP E CE3 1 
ATOM   9666  C  CZ2 . TRP E 1 71  ? 10.903  -11.547 63.056  1.00 33.50  ? 71  TRP E CZ2 1 
ATOM   9667  C  CZ3 . TRP E 1 71  ? 10.992  -12.147 60.713  1.00 31.07  ? 71  TRP E CZ3 1 
ATOM   9668  C  CH2 . TRP E 1 71  ? 11.244  -11.253 61.751  1.00 32.75  ? 71  TRP E CH2 1 
ATOM   9669  N  N   . ASP E 1 72  ? 9.812   -18.369 64.338  1.00 34.40  ? 72  ASP E N   1 
ATOM   9670  C  CA  . ASP E 1 72  ? 9.854   -18.784 65.730  1.00 32.55  ? 72  ASP E CA  1 
ATOM   9671  C  C   . ASP E 1 72  ? 11.080  -19.641 66.000  1.00 32.38  ? 72  ASP E C   1 
ATOM   9672  O  O   . ASP E 1 72  ? 11.636  -19.544 67.082  1.00 32.13  ? 72  ASP E O   1 
ATOM   9673  C  CB  . ASP E 1 72  ? 8.574   -19.507 66.111  1.00 37.36  ? 72  ASP E CB  1 
ATOM   9674  C  CG  . ASP E 1 72  ? 7.339   -18.617 66.185  1.00 39.73  ? 72  ASP E CG  1 
ATOM   9675  O  OD1 . ASP E 1 72  ? 7.481   -17.427 66.446  1.00 34.95  ? 72  ASP E OD1 1 
ATOM   9676  O  OD2 . ASP E 1 72  ? 6.233   -19.128 65.970  1.00 53.44  ? 72  ASP E OD2 1 
ATOM   9677  N  N   . ARG E 1 73  ? 11.569  -20.411 65.022  1.00 33.82  ? 73  ARG E N   1 
ATOM   9678  C  CA  . ARG E 1 73  ? 12.810  -21.158 65.213  1.00 29.54  ? 73  ARG E CA  1 
ATOM   9679  C  C   . ARG E 1 73  ? 14.015  -20.237 65.227  1.00 33.03  ? 73  ARG E C   1 
ATOM   9680  O  O   . ARG E 1 73  ? 15.022  -20.606 65.810  1.00 30.14  ? 73  ARG E O   1 
ATOM   9681  C  CB  . ARG E 1 73  ? 13.016  -22.230 64.128  1.00 28.94  ? 73  ARG E CB  1 
ATOM   9682  C  CG  . ARG E 1 73  ? 11.930  -23.290 64.161  1.00 25.92  ? 73  ARG E CG  1 
ATOM   9683  C  CD  . ARG E 1 73  ? 11.864  -24.078 62.906  1.00 26.06  ? 73  ARG E CD  1 
ATOM   9684  N  NE  . ARG E 1 73  ? 13.142  -24.746 62.704  1.00 26.33  ? 73  ARG E NE  1 
ATOM   9685  C  CZ  . ARG E 1 73  ? 13.402  -25.516 61.661  1.00 28.47  ? 73  ARG E CZ  1 
ATOM   9686  N  NH1 . ARG E 1 73  ? 12.510  -25.625 60.690  1.00 29.20  ? 73  ARG E NH1 1 
ATOM   9687  N  NH2 . ARG E 1 73  ? 14.548  -26.178 61.575  1.00 32.46  ? 73  ARG E NH2 1 
ATOM   9688  N  N   . LEU E 1 74  ? 13.941  -19.077 64.545  1.00 38.08  ? 74  LEU E N   1 
ATOM   9689  C  CA  . LEU E 1 74  ? 15.155  -18.344 64.232  1.00 35.78  ? 74  LEU E CA  1 
ATOM   9690  C  C   . LEU E 1 74  ? 15.367  -17.219 65.206  1.00 32.61  ? 74  LEU E C   1 
ATOM   9691  O  O   . LEU E 1 74  ? 16.498  -16.809 65.390  1.00 37.57  ? 74  LEU E O   1 
ATOM   9692  C  CB  . LEU E 1 74  ? 15.118  -17.791 62.817  1.00 35.17  ? 74  LEU E CB  1 
ATOM   9693  C  CG  . LEU E 1 74  ? 15.336  -18.809 61.693  1.00 33.59  ? 74  LEU E CG  1 
ATOM   9694  C  CD1 . LEU E 1 74  ? 15.059  -18.154 60.344  1.00 37.35  ? 74  LEU E CD1 1 
ATOM   9695  C  CD2 . LEU E 1 74  ? 16.759  -19.354 61.764  1.00 29.01  ? 74  LEU E CD2 1 
ATOM   9696  N  N   . PHE E 1 75  ? 14.274  -16.664 65.700  1.00 32.99  ? 75  PHE E N   1 
ATOM   9697  C  CA  . PHE E 1 75  ? 14.324  -15.421 66.447  1.00 36.41  ? 75  PHE E CA  1 
ATOM   9698  C  C   . PHE E 1 75  ? 13.478  -15.589 67.695  1.00 43.88  ? 75  PHE E C   1 
ATOM   9699  O  O   . PHE E 1 75  ? 12.531  -16.369 67.725  1.00 50.89  ? 75  PHE E O   1 
ATOM   9700  C  CB  . PHE E 1 75  ? 13.760  -14.237 65.667  1.00 33.67  ? 75  PHE E CB  1 
ATOM   9701  C  CG  . PHE E 1 75  ? 14.338  -14.125 64.268  1.00 36.08  ? 75  PHE E CG  1 
ATOM   9702  C  CD1 . PHE E 1 75  ? 15.692  -13.895 64.093  1.00 37.86  ? 75  PHE E CD1 1 
ATOM   9703  C  CD2 . PHE E 1 75  ? 13.547  -14.268 63.139  1.00 40.58  ? 75  PHE E CD2 1 
ATOM   9704  C  CE1 . PHE E 1 75  ? 16.249  -13.814 62.812  1.00 41.48  ? 75  PHE E CE1 1 
ATOM   9705  C  CE2 . PHE E 1 75  ? 14.101  -14.185 61.867  1.00 41.65  ? 75  PHE E CE2 1 
ATOM   9706  C  CZ  . PHE E 1 75  ? 15.452  -13.959 61.700  1.00 39.80  ? 75  PHE E CZ  1 
ATOM   9707  N  N   . SER E 1 76  ? 13.821  -14.857 68.738  1.00 55.69  ? 76  SER E N   1 
ATOM   9708  C  CA  . SER E 1 76  ? 12.851  -14.650 69.796  1.00 58.33  ? 76  SER E CA  1 
ATOM   9709  C  C   . SER E 1 76  ? 12.635  -13.152 69.919  1.00 52.18  ? 76  SER E C   1 
ATOM   9710  O  O   . SER E 1 76  ? 13.266  -12.348 69.238  1.00 53.00  ? 76  SER E O   1 
ATOM   9711  C  CB  . SER E 1 76  ? 13.221  -15.324 71.092  1.00 65.69  ? 76  SER E CB  1 
ATOM   9712  O  OG  . SER E 1 76  ? 14.616  -15.230 71.309  1.00 78.25  ? 76  SER E OG  1 
ATOM   9713  N  N   . GLY E 1 77  ? 11.613  -12.821 70.689  1.00 47.54  ? 77  GLY E N   1 
ATOM   9714  C  CA  . GLY E 1 77  ? 11.116  -11.473 70.721  1.00 49.50  ? 77  GLY E CA  1 
ATOM   9715  C  C   . GLY E 1 77  ? 9.880   -11.379 69.852  1.00 44.62  ? 77  GLY E C   1 
ATOM   9716  O  O   . GLY E 1 77  ? 9.215   -12.367 69.570  1.00 51.52  ? 77  GLY E O   1 
ATOM   9717  N  N   . ALA E 1 78  ? 9.610   -10.165 69.402  1.00 47.12  ? 78  ALA E N   1 
ATOM   9718  C  CA  . ALA E 1 78  ? 8.377   -9.851  68.723  1.00 48.01  ? 78  ALA E CA  1 
ATOM   9719  C  C   . ALA E 1 78  ? 8.291   -10.644 67.421  1.00 43.22  ? 78  ALA E C   1 
ATOM   9720  O  O   . ALA E 1 78  ? 9.321   -10.919 66.796  1.00 42.96  ? 78  ALA E O   1 
ATOM   9721  C  CB  . ALA E 1 78  ? 8.352   -8.345  68.498  1.00 52.13  ? 78  ALA E CB  1 
ATOM   9722  N  N   . ARG E 1 79  ? 7.052   -11.001 67.036  1.00 42.86  ? 79  ARG E N   1 
ATOM   9723  C  CA  . ARG E 1 79  ? 6.715   -11.420 65.691  1.00 35.91  ? 79  ARG E CA  1 
ATOM   9724  C  C   . ARG E 1 79  ? 6.091   -10.250 64.932  1.00 39.55  ? 79  ARG E C   1 
ATOM   9725  O  O   . ARG E 1 79  ? 5.417   -9.391  65.497  1.00 40.61  ? 79  ARG E O   1 
ATOM   9726  C  CB  . ARG E 1 79  ? 5.685   -12.537 65.740  1.00 34.72  ? 79  ARG E CB  1 
ATOM   9727  C  CG  . ARG E 1 79  ? 6.352   -13.764 66.334  1.00 35.91  ? 79  ARG E CG  1 
ATOM   9728  C  CD  . ARG E 1 79  ? 5.353   -14.866 66.484  1.00 35.20  ? 79  ARG E CD  1 
ATOM   9729  N  NE  . ARG E 1 79  ? 4.532   -14.973 65.282  1.00 36.84  ? 79  ARG E NE  1 
ATOM   9730  C  CZ  . ARG E 1 79  ? 4.766   -15.853 64.338  1.00 38.17  ? 79  ARG E CZ  1 
ATOM   9731  N  NH1 . ARG E 1 79  ? 5.773   -16.709 64.403  1.00 34.91  ? 79  ARG E NH1 1 
ATOM   9732  N  NH2 . ARG E 1 79  ? 3.955   -15.896 63.315  1.00 42.28  ? 79  ARG E NH2 1 
ATOM   9733  N  N   . PRO E 1 80  ? 6.286   -10.170 63.599  1.00 45.81  ? 80  PRO E N   1 
ATOM   9734  C  CA  . PRO E 1 80  ? 5.507   -9.220  62.804  1.00 39.92  ? 80  PRO E CA  1 
ATOM   9735  C  C   . PRO E 1 80  ? 4.035   -9.529  63.042  1.00 34.03  ? 80  PRO E C   1 
ATOM   9736  O  O   . PRO E 1 80  ? 3.650   -10.702 63.063  1.00 33.54  ? 80  PRO E O   1 
ATOM   9737  C  CB  . PRO E 1 80  ? 5.969   -9.563  61.384  1.00 42.56  ? 80  PRO E CB  1 
ATOM   9738  C  CG  . PRO E 1 80  ? 7.364   -10.127 61.584  1.00 43.41  ? 80  PRO E CG  1 
ATOM   9739  C  CD  . PRO E 1 80  ? 7.240   -10.991 62.811  1.00 43.33  ? 80  PRO E CD  1 
ATOM   9740  N  N   . ALA E 1 81  ? 3.237   -8.471  63.186  1.00 32.78  ? 81  ALA E N   1 
ATOM   9741  C  CA  . ALA E 1 81  ? 1.800   -8.561  63.458  1.00 34.18  ? 81  ALA E CA  1 
ATOM   9742  C  C   . ALA E 1 81  ? 1.047   -9.524  62.526  1.00 36.53  ? 81  ALA E C   1 
ATOM   9743  O  O   . ALA E 1 81  ? 0.170   -10.255 62.968  1.00 36.31  ? 81  ALA E O   1 
ATOM   9744  C  CB  . ALA E 1 81  ? 1.179   -7.175  63.390  1.00 30.91  ? 81  ALA E CB  1 
ATOM   9745  N  N   . GLY E 1 82  ? 1.379   -9.545  61.227  1.00 35.35  ? 82  GLY E N   1 
ATOM   9746  C  CA  . GLY E 1 82  ? 0.554   -10.211 60.237  1.00 29.92  ? 82  GLY E CA  1 
ATOM   9747  C  C   . GLY E 1 82  ? 1.032   -11.606 59.887  1.00 33.33  ? 82  GLY E C   1 
ATOM   9748  O  O   . GLY E 1 82  ? 0.426   -12.241 59.030  1.00 40.21  ? 82  GLY E O   1 
ATOM   9749  N  N   . LEU E 1 83  ? 2.106   -12.086 60.530  1.00 32.91  ? 83  LEU E N   1 
ATOM   9750  C  CA  . LEU E 1 83  ? 2.773   -13.285 60.049  1.00 30.63  ? 83  LEU E CA  1 
ATOM   9751  C  C   . LEU E 1 83  ? 2.045   -14.545 60.525  1.00 27.00  ? 83  LEU E C   1 
ATOM   9752  O  O   . LEU E 1 83  ? 1.894   -14.753 61.700  1.00 28.08  ? 83  LEU E O   1 
ATOM   9753  C  CB  . LEU E 1 83  ? 4.231   -13.218 60.491  1.00 30.34  ? 83  LEU E CB  1 
ATOM   9754  C  CG  . LEU E 1 83  ? 5.088   -14.387 59.994  1.00 34.56  ? 83  LEU E CG  1 
ATOM   9755  C  CD1 . LEU E 1 83  ? 5.050   -14.579 58.477  1.00 33.32  ? 83  LEU E CD1 1 
ATOM   9756  C  CD2 . LEU E 1 83  ? 6.513   -14.216 60.500  1.00 39.79  ? 83  LEU E CD2 1 
ATOM   9757  N  N   . HIS E 1 84  ? 1.539   -15.347 59.599  1.00 26.11  ? 84  HIS E N   1 
ATOM   9758  C  CA  . HIS E 1 84  ? 0.879   -16.617 59.853  1.00 24.82  ? 84  HIS E CA  1 
ATOM   9759  C  C   . HIS E 1 84  ? 1.126   -17.511 58.635  1.00 25.64  ? 84  HIS E C   1 
ATOM   9760  O  O   . HIS E 1 84  ? 1.602   -17.064 57.589  1.00 27.52  ? 84  HIS E O   1 
ATOM   9761  C  CB  . HIS E 1 84  ? -0.643  -16.470 60.080  1.00 25.67  ? 84  HIS E CB  1 
ATOM   9762  C  CG  . HIS E 1 84  ? -1.325  -15.552 59.127  1.00 25.02  ? 84  HIS E CG  1 
ATOM   9763  N  ND1 . HIS E 1 84  ? -1.574  -14.221 59.402  1.00 27.58  ? 84  HIS E ND1 1 
ATOM   9764  C  CD2 . HIS E 1 84  ? -1.754  -15.752 57.868  1.00 24.07  ? 84  HIS E CD2 1 
ATOM   9765  C  CE1 . HIS E 1 84  ? -2.156  -13.645 58.336  1.00 26.84  ? 84  HIS E CE1 1 
ATOM   9766  N  NE2 . HIS E 1 84  ? -2.240  -14.551 57.380  1.00 26.34  ? 84  HIS E NE2 1 
ATOM   9767  N  N   . PRO E 1 85  ? 0.842   -18.823 58.725  1.00 25.47  ? 85  PRO E N   1 
ATOM   9768  C  CA  . PRO E 1 85  ? 0.885   -19.702 57.568  1.00 25.09  ? 85  PRO E CA  1 
ATOM   9769  C  C   . PRO E 1 85  ? -0.148  -19.308 56.547  1.00 26.26  ? 85  PRO E C   1 
ATOM   9770  O  O   . PRO E 1 85  ? -1.168  -18.758 56.905  1.00 25.87  ? 85  PRO E O   1 
ATOM   9771  C  CB  . PRO E 1 85  ? 0.573   -21.064 58.161  1.00 27.42  ? 85  PRO E CB  1 
ATOM   9772  C  CG  . PRO E 1 85  ? 1.082   -20.920 59.571  1.00 26.89  ? 85  PRO E CG  1 
ATOM   9773  C  CD  . PRO E 1 85  ? 0.561   -19.554 59.961  1.00 27.04  ? 85  PRO E CD  1 
ATOM   9774  N  N   . PHE E 1 86  ? 0.188   -19.577 55.290  1.00 32.29  ? 86  PHE E N   1 
ATOM   9775  C  CA  . PHE E 1 86  ? -0.705  -19.331 54.172  1.00 34.70  ? 86  PHE E CA  1 
ATOM   9776  C  C   . PHE E 1 86  ? -1.977  -20.111 54.470  1.00 33.44  ? 86  PHE E C   1 
ATOM   9777  O  O   . PHE E 1 86  ? -1.848  -21.259 54.885  1.00 36.26  ? 86  PHE E O   1 
ATOM   9778  C  CB  . PHE E 1 86  ? -0.001  -19.792 52.884  1.00 32.86  ? 86  PHE E CB  1 
ATOM   9779  C  CG  . PHE E 1 86  ? -0.819  -19.595 51.621  1.00 31.51  ? 86  PHE E CG  1 
ATOM   9780  C  CD1 . PHE E 1 86  ? -0.756  -18.397 50.939  1.00 33.52  ? 86  PHE E CD1 1 
ATOM   9781  C  CD2 . PHE E 1 86  ? -1.654  -20.590 51.124  1.00 31.72  ? 86  PHE E CD2 1 
ATOM   9782  C  CE1 . PHE E 1 86  ? -1.474  -18.210 49.771  1.00 33.59  ? 86  PHE E CE1 1 
ATOM   9783  C  CE2 . PHE E 1 86  ? -2.383  -20.397 49.961  1.00 30.40  ? 86  PHE E CE2 1 
ATOM   9784  C  CZ  . PHE E 1 86  ? -2.305  -19.204 49.294  1.00 32.36  ? 86  PHE E CZ  1 
ATOM   9785  N  N   . ARG E 1 87  ? -3.148  -19.488 54.264  1.00 32.43  ? 87  ARG E N   1 
ATOM   9786  C  CA  . ARG E 1 87  ? -4.430  -20.128 54.512  1.00 35.56  ? 87  ARG E CA  1 
ATOM   9787  C  C   . ARG E 1 87  ? -4.954  -20.730 53.215  1.00 33.66  ? 87  ARG E C   1 
ATOM   9788  O  O   . ARG E 1 87  ? -5.287  -19.969 52.303  1.00 27.62  ? 87  ARG E O   1 
ATOM   9789  C  CB  . ARG E 1 87  ? -5.531  -19.179 55.001  1.00 47.85  ? 87  ARG E CB  1 
ATOM   9790  C  CG  . ARG E 1 87  ? -5.085  -17.983 55.836  1.00 64.04  ? 87  ARG E CG  1 
ATOM   9791  C  CD  . ARG E 1 87  ? -6.184  -17.002 56.183  1.00 81.14  ? 87  ARG E CD  1 
ATOM   9792  N  NE  . ARG E 1 87  ? -5.925  -16.998 57.628  1.00 96.78  ? 87  ARG E NE  1 
ATOM   9793  C  CZ  . ARG E 1 87  ? -5.354  -16.057 58.356  1.00 89.89  ? 87  ARG E CZ  1 
ATOM   9794  N  NH1 . ARG E 1 87  ? -5.447  -14.788 57.966  1.00 88.60  ? 87  ARG E NH1 1 
ATOM   9795  N  NH2 . ARG E 1 87  ? -4.760  -16.406 59.504  1.00 72.53  ? 87  ARG E NH2 1 
ATOM   9796  N  N   . GLU E 1 88  ? -5.036  -22.082 53.180  1.00 33.09  ? 88  GLU E N   1 
ATOM   9797  C  CA  . GLU E 1 88  ? -5.741  -22.870 52.184  1.00 33.20  ? 88  GLU E CA  1 
ATOM   9798  C  C   . GLU E 1 88  ? -7.099  -22.228 51.934  1.00 33.11  ? 88  GLU E C   1 
ATOM   9799  O  O   . GLU E 1 88  ? -7.694  -21.708 52.873  1.00 32.85  ? 88  GLU E O   1 
ATOM   9800  C  CB  . GLU E 1 88  ? -6.130  -24.284 52.636  1.00 37.32  ? 88  GLU E CB  1 
ATOM   9801  C  CG  . GLU E 1 88  ? -5.004  -25.226 53.048  1.00 52.08  ? 88  GLU E CG  1 
ATOM   9802  C  CD  . GLU E 1 88  ? -4.834  -26.438 52.131  1.00 64.59  ? 88  GLU E CD  1 
ATOM   9803  O  OE1 . GLU E 1 88  ? -5.862  -26.991 51.689  1.00 65.44  ? 88  GLU E OE1 1 
ATOM   9804  O  OE2 . GLU E 1 88  ? -3.670  -26.812 51.821  1.00 68.22  ? 88  GLU E OE2 1 
ATOM   9805  N  N   . LEU E 1 89  ? -7.546  -22.192 50.664  1.00 37.73  ? 89  LEU E N   1 
ATOM   9806  C  CA  . LEU E 1 89  ? -8.895  -21.777 50.319  1.00 33.36  ? 89  LEU E CA  1 
ATOM   9807  C  C   . LEU E 1 89  ? -9.505  -22.884 49.476  1.00 37.34  ? 89  LEU E C   1 
ATOM   9808  O  O   . LEU E 1 89  ? -9.016  -23.190 48.383  1.00 34.95  ? 89  LEU E O   1 
ATOM   9809  C  CB  . LEU E 1 89  ? -8.969  -20.462 49.563  1.00 30.96  ? 89  LEU E CB  1 
ATOM   9810  C  CG  . LEU E 1 89  ? -8.398  -19.231 50.250  1.00 30.54  ? 89  LEU E CG  1 
ATOM   9811  C  CD1 . LEU E 1 89  ? -8.520  -18.049 49.306  1.00 34.24  ? 89  LEU E CD1 1 
ATOM   9812  C  CD2 . LEU E 1 89  ? -9.053  -18.943 51.558  1.00 30.58  ? 89  LEU E CD2 1 
ATOM   9813  N  N   . ASP E 1 90  ? -10.556 -23.501 50.043  1.00 48.27  ? 90  ASP E N   1 
ATOM   9814  C  CA  . ASP E 1 90  ? -11.261 -24.619 49.442  1.00 46.17  ? 90  ASP E CA  1 
ATOM   9815  C  C   . ASP E 1 90  ? -12.549 -24.067 48.836  1.00 38.85  ? 90  ASP E C   1 
ATOM   9816  O  O   . ASP E 1 90  ? -13.549 -23.904 49.513  1.00 41.83  ? 90  ASP E O   1 
ATOM   9817  C  CB  . ASP E 1 90  ? -11.370 -25.763 50.431  1.00 47.48  ? 90  ASP E CB  1 
ATOM   9818  C  CG  . ASP E 1 90  ? -11.562 -27.098 49.748  1.00 55.91  ? 90  ASP E CG  1 
ATOM   9819  O  OD1 . ASP E 1 90  ? -10.706 -27.483 48.920  1.00 63.90  ? 90  ASP E OD1 1 
ATOM   9820  O  OD2 . ASP E 1 90  ? -12.604 -27.702 50.004  1.00 80.75  ? 90  ASP E OD2 1 
ATOM   9821  N  N   . GLY E 1 91  ? -12.467 -23.691 47.569  1.00 34.67  ? 91  GLY E N   1 
ATOM   9822  C  CA  . GLY E 1 91  ? -13.566 -23.035 46.909  1.00 41.15  ? 91  GLY E CA  1 
ATOM   9823  C  C   . GLY E 1 91  ? -14.517 -24.074 46.334  1.00 42.56  ? 91  GLY E C   1 
ATOM   9824  O  O   . GLY E 1 91  ? -14.179 -25.259 46.269  1.00 41.36  ? 91  GLY E O   1 
ATOM   9825  N  N   . PRO E 1 92  ? -15.731 -23.647 45.910  1.00 44.66  ? 92  PRO E N   1 
ATOM   9826  C  CA  . PRO E 1 92  ? -16.683 -24.558 45.281  1.00 42.82  ? 92  PRO E CA  1 
ATOM   9827  C  C   . PRO E 1 92  ? -16.041 -25.366 44.156  1.00 48.42  ? 92  PRO E C   1 
ATOM   9828  O  O   . PRO E 1 92  ? -16.299 -26.548 44.039  1.00 44.75  ? 92  PRO E O   1 
ATOM   9829  C  CB  . PRO E 1 92  ? -17.817 -23.640 44.754  1.00 44.99  ? 92  PRO E CB  1 
ATOM   9830  C  CG  . PRO E 1 92  ? -17.377 -22.183 45.019  1.00 44.45  ? 92  PRO E CG  1 
ATOM   9831  C  CD  . PRO E 1 92  ? -16.241 -22.264 46.030  1.00 44.34  ? 92  PRO E CD  1 
ATOM   9832  N  N   . VAL E 1 93  ? -15.203 -24.724 43.328  1.00 50.13  ? 93  VAL E N   1 
ATOM   9833  C  CA  . VAL E 1 93  ? -14.633 -25.340 42.139  1.00 40.61  ? 93  VAL E CA  1 
ATOM   9834  C  C   . VAL E 1 93  ? -13.118 -25.389 42.258  1.00 36.15  ? 93  VAL E C   1 
ATOM   9835  O  O   . VAL E 1 93  ? -12.501 -26.369 41.868  1.00 38.70  ? 93  VAL E O   1 
ATOM   9836  C  CB  . VAL E 1 93  ? -15.038 -24.521 40.893  1.00 38.98  ? 93  VAL E CB  1 
ATOM   9837  C  CG1 . VAL E 1 93  ? -14.277 -24.966 39.654  1.00 43.55  ? 93  VAL E CG1 1 
ATOM   9838  C  CG2 . VAL E 1 93  ? -16.518 -24.586 40.627  1.00 36.05  ? 93  VAL E CG2 1 
ATOM   9839  N  N   . HIS E 1 94  ? -12.517 -24.271 42.687  1.00 32.71  ? 94  HIS E N   1 
ATOM   9840  C  CA  . HIS E 1 94  ? -11.079 -24.111 42.658  1.00 32.17  ? 94  HIS E CA  1 
ATOM   9841  C  C   . HIS E 1 94  ? -10.526 -24.048 44.084  1.00 33.44  ? 94  HIS E C   1 
ATOM   9842  O  O   . HIS E 1 94  ? -11.147 -23.443 44.954  1.00 45.36  ? 94  HIS E O   1 
ATOM   9843  C  CB  . HIS E 1 94  ? -10.741 -22.835 41.868  1.00 32.22  ? 94  HIS E CB  1 
ATOM   9844  C  CG  . HIS E 1 94  ? -11.106 -22.846 40.432  1.00 29.09  ? 94  HIS E CG  1 
ATOM   9845  N  ND1 . HIS E 1 94  ? -10.607 -23.750 39.517  1.00 27.31  ? 94  HIS E ND1 1 
ATOM   9846  C  CD2 . HIS E 1 94  ? -12.004 -22.096 39.782  1.00 29.82  ? 94  HIS E CD2 1 
ATOM   9847  C  CE1 . HIS E 1 94  ? -11.176 -23.514 38.331  1.00 30.27  ? 94  HIS E CE1 1 
ATOM   9848  N  NE2 . HIS E 1 94  ? -12.040 -22.518 38.472  1.00 32.29  ? 94  HIS E NE2 1 
ATOM   9849  N  N   . ARG E 1 95  ? -9.282  -24.505 44.262  1.00 35.06  ? 95  ARG E N   1 
ATOM   9850  C  CA  . ARG E 1 95  ? -8.579  -24.550 45.545  1.00 38.33  ? 95  ARG E CA  1 
ATOM   9851  C  C   . ARG E 1 95  ? -7.242  -23.784 45.509  1.00 34.34  ? 95  ARG E C   1 
ATOM   9852  O  O   . ARG E 1 95  ? -6.464  -23.921 44.583  1.00 32.35  ? 95  ARG E O   1 
ATOM   9853  C  CB  . ARG E 1 95  ? -8.408  -26.064 45.650  1.00 39.68  ? 95  ARG E CB  1 
ATOM   9854  C  CG  . ARG E 1 95  ? -7.758  -26.725 46.837  1.00 47.70  ? 95  ARG E CG  1 
ATOM   9855  C  CD  . ARG E 1 95  ? -8.108  -28.249 46.646  1.00 59.94  ? 95  ARG E CD  1 
ATOM   9856  N  NE  . ARG E 1 95  ? -7.986  -28.858 47.973  1.00 70.00  ? 95  ARG E NE  1 
ATOM   9857  C  CZ  . ARG E 1 95  ? -6.823  -28.886 48.636  1.00 79.11  ? 95  ARG E CZ  1 
ATOM   9858  N  NH1 . ARG E 1 95  ? -5.721  -29.250 48.008  1.00 79.88  ? 95  ARG E NH1 1 
ATOM   9859  N  NH2 . ARG E 1 95  ? -6.768  -28.673 49.945  1.00 78.82  ? 95  ARG E NH2 1 
ATOM   9860  N  N   . ALA E 1 96  ? -6.970  -22.953 46.507  1.00 33.47  ? 96  ALA E N   1 
ATOM   9861  C  CA  . ALA E 1 96  ? -5.653  -22.351 46.687  1.00 30.01  ? 96  ALA E CA  1 
ATOM   9862  C  C   . ALA E 1 96  ? -4.881  -23.183 47.707  1.00 29.20  ? 96  ALA E C   1 
ATOM   9863  O  O   . ALA E 1 96  ? -5.203  -23.176 48.887  1.00 34.04  ? 96  ALA E O   1 
ATOM   9864  C  CB  . ALA E 1 96  ? -5.808  -20.898 47.124  1.00 26.22  ? 96  ALA E CB  1 
ATOM   9865  N  N   . VAL E 1 97  ? -3.877  -23.928 47.270  1.00 29.72  ? 97  VAL E N   1 
ATOM   9866  C  CA  . VAL E 1 97  ? -3.217  -24.853 48.183  1.00 30.09  ? 97  VAL E CA  1 
ATOM   9867  C  C   . VAL E 1 97  ? -2.154  -24.131 48.975  1.00 28.65  ? 97  VAL E C   1 
ATOM   9868  O  O   . VAL E 1 97  ? -1.727  -23.051 48.575  1.00 29.74  ? 97  VAL E O   1 
ATOM   9869  C  CB  . VAL E 1 97  ? -2.579  -26.068 47.507  1.00 32.81  ? 97  VAL E CB  1 
ATOM   9870  C  CG1 . VAL E 1 97  ? -3.628  -26.875 46.789  1.00 34.60  ? 97  VAL E CG1 1 
ATOM   9871  C  CG2 . VAL E 1 97  ? -1.504  -25.664 46.534  1.00 33.43  ? 97  VAL E CG2 1 
ATOM   9872  N  N   . ALA E 1 98  ? -1.739  -24.825 50.039  1.00 30.19  ? 98  ALA E N   1 
ATOM   9873  C  CA  . ALA E 1 98  ? -0.659  -24.431 50.936  1.00 31.26  ? 98  ALA E CA  1 
ATOM   9874  C  C   . ALA E 1 98  ? 0.440   -25.466 50.817  1.00 30.66  ? 98  ALA E C   1 
ATOM   9875  O  O   . ALA E 1 98  ? 0.165   -26.659 50.931  1.00 32.09  ? 98  ALA E O   1 
ATOM   9876  C  CB  . ALA E 1 98  ? -1.150  -24.355 52.372  1.00 29.34  ? 98  ALA E CB  1 
ATOM   9877  N  N   . THR E 1 99  ? 1.663   -25.012 50.572  1.00 29.82  ? 99  THR E N   1 
ATOM   9878  C  CA  . THR E 1 99  ? 2.795   -25.925 50.515  1.00 30.04  ? 99  THR E CA  1 
ATOM   9879  C  C   . THR E 1 99  ? 3.874   -25.376 51.437  1.00 25.88  ? 99  THR E C   1 
ATOM   9880  O  O   . THR E 1 99  ? 3.862   -24.211 51.794  1.00 21.89  ? 99  THR E O   1 
ATOM   9881  C  CB  . THR E 1 99  ? 3.303   -26.136 49.084  1.00 30.40  ? 99  THR E CB  1 
ATOM   9882  O  OG1 . THR E 1 99  ? 3.559   -24.854 48.540  1.00 28.20  ? 99  THR E OG1 1 
ATOM   9883  C  CG2 . THR E 1 99  ? 2.247   -26.722 48.180  1.00 32.47  ? 99  THR E CG2 1 
ATOM   9884  N  N   . PRO E 1 100 ? 4.794   -26.230 51.914  1.00 24.33  ? 100 PRO E N   1 
ATOM   9885  C  CA  . PRO E 1 100 ? 5.799   -25.824 52.896  1.00 26.42  ? 100 PRO E CA  1 
ATOM   9886  C  C   . PRO E 1 100 ? 6.832   -24.854 52.337  1.00 27.54  ? 100 PRO E C   1 
ATOM   9887  O  O   . PRO E 1 100 ? 7.266   -25.021 51.207  1.00 26.91  ? 100 PRO E O   1 
ATOM   9888  C  CB  . PRO E 1 100 ? 6.498   -27.116 53.307  1.00 27.34  ? 100 PRO E CB  1 
ATOM   9889  C  CG  . PRO E 1 100 ? 5.700   -28.248 52.649  1.00 25.13  ? 100 PRO E CG  1 
ATOM   9890  C  CD  . PRO E 1 100 ? 4.866   -27.649 51.557  1.00 24.61  ? 100 PRO E CD  1 
ATOM   9891  N  N   . GLY E 1 101 ? 7.253   -23.896 53.160  1.00 23.75  ? 101 GLY E N   1 
ATOM   9892  C  CA  . GLY E 1 101 ? 8.339   -23.011 52.814  1.00 24.09  ? 101 GLY E CA  1 
ATOM   9893  C  C   . GLY E 1 101 ? 8.746   -22.174 54.014  1.00 25.36  ? 101 GLY E C   1 
ATOM   9894  O  O   . GLY E 1 101 ? 7.937   -21.394 54.509  1.00 29.76  ? 101 GLY E O   1 
ATOM   9895  N  N   . ASP E 1 102 ? 10.007  -22.280 54.417  1.00 24.08  ? 102 ASP E N   1 
ATOM   9896  C  CA  . ASP E 1 102 ? 10.513  -21.495 55.523  1.00 25.85  ? 102 ASP E CA  1 
ATOM   9897  C  C   . ASP E 1 102 ? 11.210  -20.226 55.040  1.00 24.09  ? 102 ASP E C   1 
ATOM   9898  O  O   . ASP E 1 102 ? 11.119  -19.207 55.693  1.00 27.27  ? 102 ASP E O   1 
ATOM   9899  C  CB  . ASP E 1 102 ? 11.453  -22.322 56.378  1.00 26.16  ? 102 ASP E CB  1 
ATOM   9900  C  CG  . ASP E 1 102 ? 10.788  -23.509 57.048  1.00 30.00  ? 102 ASP E CG  1 
ATOM   9901  O  OD1 . ASP E 1 102 ? 9.631   -23.323 57.459  1.00 27.26  ? 102 ASP E OD1 1 
ATOM   9902  O  OD2 . ASP E 1 102 ? 11.431  -24.577 57.171  1.00 26.16  ? 102 ASP E OD2 1 
ATOM   9903  N  N   . LEU E 1 103 ? 11.971  -20.309 53.946  1.00 24.63  ? 103 LEU E N   1 
ATOM   9904  C  CA  . LEU E 1 103 ? 12.715  -19.174 53.425  1.00 24.90  ? 103 LEU E CA  1 
ATOM   9905  C  C   . LEU E 1 103 ? 12.361  -18.987 51.968  1.00 24.68  ? 103 LEU E C   1 
ATOM   9906  O  O   . LEU E 1 103 ? 12.166  -19.973 51.261  1.00 30.50  ? 103 LEU E O   1 
ATOM   9907  C  CB  . LEU E 1 103 ? 14.206  -19.441 53.520  1.00 25.31  ? 103 LEU E CB  1 
ATOM   9908  C  CG  . LEU E 1 103 ? 14.805  -19.529 54.927  1.00 25.46  ? 103 LEU E CG  1 
ATOM   9909  C  CD1 . LEU E 1 103 ? 16.295  -19.792 54.809  1.00 24.30  ? 103 LEU E CD1 1 
ATOM   9910  C  CD2 . LEU E 1 103 ? 14.554  -18.244 55.719  1.00 27.22  ? 103 LEU E CD2 1 
ATOM   9911  N  N   . LEU E 1 104 ? 12.325  -17.727 51.545  1.00 21.34  ? 104 LEU E N   1 
ATOM   9912  C  CA  . LEU E 1 104 ? 12.103  -17.310 50.165  1.00 21.91  ? 104 LEU E CA  1 
ATOM   9913  C  C   . LEU E 1 104 ? 13.294  -16.463 49.731  1.00 22.12  ? 104 LEU E C   1 
ATOM   9914  O  O   . LEU E 1 104 ? 13.667  -15.543 50.437  1.00 23.70  ? 104 LEU E O   1 
ATOM   9915  C  CB  . LEU E 1 104 ? 10.831  -16.466 50.041  1.00 21.88  ? 104 LEU E CB  1 
ATOM   9916  C  CG  . LEU E 1 104 ? 10.651  -15.679 48.736  1.00 22.42  ? 104 LEU E CG  1 
ATOM   9917  C  CD1 . LEU E 1 104 ? 10.271  -16.606 47.600  1.00 25.24  ? 104 LEU E CD1 1 
ATOM   9918  C  CD2 . LEU E 1 104 ? 9.641   -14.565 48.853  1.00 21.59  ? 104 LEU E CD2 1 
ATOM   9919  N  N   . PHE E 1 105 ? 13.864  -16.750 48.562  1.00 22.27  ? 105 PHE E N   1 
ATOM   9920  C  CA  . PHE E 1 105 ? 14.788  -15.828 47.907  1.00 21.84  ? 105 PHE E CA  1 
ATOM   9921  C  C   . PHE E 1 105 ? 14.167  -15.436 46.578  1.00 19.88  ? 105 PHE E C   1 
ATOM   9922  O  O   . PHE E 1 105 ? 13.924  -16.280 45.735  1.00 23.39  ? 105 PHE E O   1 
ATOM   9923  C  CB  . PHE E 1 105 ? 16.192  -16.418 47.744  1.00 22.43  ? 105 PHE E CB  1 
ATOM   9924  C  CG  . PHE E 1 105 ? 16.799  -16.871 49.063  1.00 21.56  ? 105 PHE E CG  1 
ATOM   9925  C  CD1 . PHE E 1 105 ? 17.395  -15.963 49.912  1.00 22.33  ? 105 PHE E CD1 1 
ATOM   9926  C  CD2 . PHE E 1 105 ? 16.715  -18.177 49.473  1.00 22.39  ? 105 PHE E CD2 1 
ATOM   9927  C  CE1 . PHE E 1 105 ? 17.889  -16.368 51.140  1.00 24.07  ? 105 PHE E CE1 1 
ATOM   9928  C  CE2 . PHE E 1 105 ? 17.204  -18.570 50.706  1.00 24.38  ? 105 PHE E CE2 1 
ATOM   9929  C  CZ  . PHE E 1 105 ? 17.785  -17.666 51.543  1.00 22.30  ? 105 PHE E CZ  1 
ATOM   9930  N  N   . HIS E 1 106 ? 13.842  -14.167 46.433  1.00 19.06  ? 106 HIS E N   1 
ATOM   9931  C  CA  . HIS E 1 106 ? 13.283  -13.626 45.211  1.00 18.98  ? 106 HIS E CA  1 
ATOM   9932  C  C   . HIS E 1 106 ? 14.394  -12.777 44.604  1.00 21.73  ? 106 HIS E C   1 
ATOM   9933  O  O   . HIS E 1 106 ? 14.638  -11.626 45.007  1.00 23.31  ? 106 HIS E O   1 
ATOM   9934  C  CB  . HIS E 1 106 ? 12.061  -12.762 45.529  1.00 19.66  ? 106 HIS E CB  1 
ATOM   9935  C  CG  . HIS E 1 106 ? 11.412  -12.142 44.361  1.00 20.52  ? 106 HIS E CG  1 
ATOM   9936  N  ND1 . HIS E 1 106 ? 10.639  -10.999 44.452  1.00 24.55  ? 106 HIS E ND1 1 
ATOM   9937  C  CD2 . HIS E 1 106 ? 11.468  -12.445 43.084  1.00 22.12  ? 106 HIS E CD2 1 
ATOM   9938  C  CE1 . HIS E 1 106 ? 10.214  -10.661 43.249  1.00 24.68  ? 106 HIS E CE1 1 
ATOM   9939  N  NE2 . HIS E 1 106 ? 10.723  -11.524 42.393  1.00 24.59  ? 106 HIS E NE2 1 
ATOM   9940  N  N   . ILE E 1 107 ? 15.046  -13.391 43.620  1.00 23.51  ? 107 ILE E N   1 
ATOM   9941  C  CA  . ILE E 1 107 ? 16.245  -12.859 43.006  1.00 23.95  ? 107 ILE E CA  1 
ATOM   9942  C  C   . ILE E 1 107 ? 15.878  -12.347 41.629  1.00 23.23  ? 107 ILE E C   1 
ATOM   9943  O  O   . ILE E 1 107 ? 15.267  -13.088 40.864  1.00 22.22  ? 107 ILE E O   1 
ATOM   9944  C  CB  . ILE E 1 107 ? 17.307  -13.961 42.917  1.00 26.49  ? 107 ILE E CB  1 
ATOM   9945  C  CG1 . ILE E 1 107 ? 17.632  -14.532 44.265  1.00 26.22  ? 107 ILE E CG1 1 
ATOM   9946  C  CG2 . ILE E 1 107 ? 18.558  -13.429 42.234  1.00 30.04  ? 107 ILE E CG2 1 
ATOM   9947  C  CD1 . ILE E 1 107 ? 18.465  -15.790 44.179  1.00 28.11  ? 107 ILE E CD1 1 
ATOM   9948  N  N   . ARG E 1 108 ? 16.256  -11.095 41.342  1.00 24.15  ? 108 ARG E N   1 
ATOM   9949  C  CA  . ARG E 1 108 ? 15.852  -10.429 40.109  1.00 29.60  ? 108 ARG E CA  1 
ATOM   9950  C  C   . ARG E 1 108 ? 17.042  -9.725  39.472  1.00 28.69  ? 108 ARG E C   1 
ATOM   9951  O  O   . ARG E 1 108 ? 17.830  -9.143  40.190  1.00 30.32  ? 108 ARG E O   1 
ATOM   9952  C  CB  . ARG E 1 108 ? 14.767  -9.376  40.350  1.00 28.76  ? 108 ARG E CB  1 
ATOM   9953  C  CG  . ARG E 1 108 ? 13.403  -10.020 40.575  1.00 30.72  ? 108 ARG E CG  1 
ATOM   9954  C  CD  . ARG E 1 108 ? 12.407  -8.992  40.960  1.00 31.57  ? 108 ARG E CD  1 
ATOM   9955  N  NE  . ARG E 1 108 ? 12.644  -8.403  42.282  1.00 39.42  ? 108 ARG E NE  1 
ATOM   9956  C  CZ  . ARG E 1 108 ? 11.756  -7.612  42.859  1.00 34.45  ? 108 ARG E CZ  1 
ATOM   9957  N  NH1 . ARG E 1 108 ? 10.641  -7.297  42.237  1.00 34.34  ? 108 ARG E NH1 1 
ATOM   9958  N  NH2 . ARG E 1 108 ? 11.995  -7.162  44.065  1.00 34.42  ? 108 ARG E NH2 1 
ATOM   9959  N  N   . ALA E 1 109 ? 17.130  -9.767  38.139  1.00 25.38  ? 109 ALA E N   1 
ATOM   9960  C  CA  . ALA E 1 109 ? 18.100  -8.970  37.428  1.00 27.57  ? 109 ALA E CA  1 
ATOM   9961  C  C   . ALA E 1 109 ? 17.690  -8.806  35.976  1.00 28.51  ? 109 ALA E C   1 
ATOM   9962  O  O   . ALA E 1 109 ? 16.694  -9.371  35.526  1.00 23.47  ? 109 ALA E O   1 
ATOM   9963  C  CB  . ALA E 1 109 ? 19.428  -9.671  37.510  1.00 32.94  ? 109 ALA E CB  1 
ATOM   9964  N  N   . SER E 1 110 ? 18.544  -8.102  35.227  1.00 30.61  ? 110 SER E N   1 
ATOM   9965  C  CA  . SER E 1 110 ? 18.319  -7.966  33.801  1.00 31.75  ? 110 SER E CA  1 
ATOM   9966  C  C   . SER E 1 110 ? 18.760  -9.221  33.039  1.00 30.73  ? 110 SER E C   1 
ATOM   9967  O  O   . SER E 1 110 ? 18.347  -9.385  31.903  1.00 35.90  ? 110 SER E O   1 
ATOM   9968  C  CB  . SER E 1 110 ? 18.982  -6.758  33.273  1.00 32.36  ? 110 SER E CB  1 
ATOM   9969  O  OG  . SER E 1 110 ? 20.395  -6.921  33.359  1.00 35.31  ? 110 SER E OG  1 
ATOM   9970  N  N   . ARG E 1 111 ? 19.553  -10.132 33.631  1.00 26.87  ? 111 ARG E N   1 
ATOM   9971  C  CA  . ARG E 1 111 ? 20.000  -11.322 32.911  1.00 26.10  ? 111 ARG E CA  1 
ATOM   9972  C  C   . ARG E 1 111 ? 19.945  -12.526 33.844  1.00 24.61  ? 111 ARG E C   1 
ATOM   9973  O  O   . ARG E 1 111 ? 20.297  -12.399 35.011  1.00 24.16  ? 111 ARG E O   1 
ATOM   9974  C  CB  . ARG E 1 111 ? 21.483  -11.201 32.520  1.00 32.47  ? 111 ARG E CB  1 
ATOM   9975  C  CG  . ARG E 1 111 ? 21.987  -9.910  31.876  1.00 38.11  ? 111 ARG E CG  1 
ATOM   9976  C  CD  . ARG E 1 111 ? 23.523  -9.739  31.844  1.00 40.34  ? 111 ARG E CD  1 
ATOM   9977  N  NE  . ARG E 1 111 ? 24.314  -10.901 31.408  1.00 41.32  ? 111 ARG E NE  1 
ATOM   9978  C  CZ  . ARG E 1 111 ? 24.526  -11.373 30.175  1.00 38.18  ? 111 ARG E CZ  1 
ATOM   9979  N  NH1 . ARG E 1 111 ? 24.303  -10.623 29.122  1.00 41.96  ? 111 ARG E NH1 1 
ATOM   9980  N  NH2 . ARG E 1 111 ? 25.084  -12.550 29.947  1.00 38.13  ? 111 ARG E NH2 1 
ATOM   9981  N  N   . LEU E 1 112 ? 19.589  -13.702 33.331  1.00 24.48  ? 112 LEU E N   1 
ATOM   9982  C  CA  . LEU E 1 112 ? 19.440  -14.880 34.173  1.00 26.95  ? 112 LEU E CA  1 
ATOM   9983  C  C   . LEU E 1 112 ? 20.733  -15.250 34.907  1.00 31.74  ? 112 LEU E C   1 
ATOM   9984  O  O   . LEU E 1 112 ? 20.701  -15.682 36.069  1.00 30.70  ? 112 LEU E O   1 
ATOM   9985  C  CB  . LEU E 1 112 ? 18.954  -16.032 33.312  1.00 30.48  ? 112 LEU E CB  1 
ATOM   9986  C  CG  . LEU E 1 112 ? 18.523  -17.282 34.078  1.00 35.57  ? 112 LEU E CG  1 
ATOM   9987  C  CD1 . LEU E 1 112 ? 17.519  -16.926 35.177  1.00 36.48  ? 112 LEU E CD1 1 
ATOM   9988  C  CD2 . LEU E 1 112 ? 17.939  -18.328 33.131  1.00 38.61  ? 112 LEU E CD2 1 
ATOM   9989  N  N   . ASP E 1 113 ? 21.883  -15.067 34.245  1.00 30.91  ? 113 ASP E N   1 
ATOM   9990  C  CA  . ASP E 1 113 ? 23.137  -15.545 34.781  1.00 29.17  ? 113 ASP E CA  1 
ATOM   9991  C  C   . ASP E 1 113 ? 23.458  -14.840 36.084  1.00 26.78  ? 113 ASP E C   1 
ATOM   9992  O  O   . ASP E 1 113 ? 24.064  -15.467 36.948  1.00 27.72  ? 113 ASP E O   1 
ATOM   9993  C  CB  . ASP E 1 113 ? 24.317  -15.354 33.840  1.00 29.69  ? 113 ASP E CB  1 
ATOM   9994  C  CG  . ASP E 1 113 ? 24.495  -13.925 33.343  1.00 31.87  ? 113 ASP E CG  1 
ATOM   9995  O  OD1 . ASP E 1 113 ? 23.655  -13.571 32.487  1.00 31.83  ? 113 ASP E OD1 1 
ATOM   9996  O  OD2 . ASP E 1 113 ? 25.423  -13.170 33.833  1.00 29.98  ? 113 ASP E OD2 1 
ATOM   9997  N  N   . LEU E 1 114 ? 23.124  -13.553 36.206  1.00 24.20  ? 114 LEU E N   1 
ATOM   9998  C  CA  . LEU E 1 114 ? 23.361  -12.845 37.461  1.00 28.17  ? 114 LEU E CA  1 
ATOM   9999  C  C   . LEU E 1 114 ? 22.553  -13.445 38.609  1.00 29.10  ? 114 LEU E C   1 
ATOM   10000 O  O   . LEU E 1 114 ? 23.066  -13.553 39.733  1.00 25.72  ? 114 LEU E O   1 
ATOM   10001 C  CB  . LEU E 1 114 ? 23.020  -11.369 37.314  1.00 28.92  ? 114 LEU E CB  1 
ATOM   10002 C  CG  . LEU E 1 114 ? 24.060  -10.565 36.534  1.00 34.06  ? 114 LEU E CG  1 
ATOM   10003 C  CD1 . LEU E 1 114 ? 23.555  -9.148  36.323  1.00 35.18  ? 114 LEU E CD1 1 
ATOM   10004 C  CD2 . LEU E 1 114 ? 25.433  -10.557 37.241  1.00 32.80  ? 114 LEU E CD2 1 
ATOM   10005 N  N   . CYS E 1 115 ? 21.283  -13.760 38.311  1.00 24.56  ? 115 CYS E N   1 
ATOM   10006 C  CA  . CYS E 1 115 ? 20.408  -14.407 39.257  1.00 23.01  ? 115 CYS E CA  1 
ATOM   10007 C  C   . CYS E 1 115 ? 21.035  -15.717 39.691  1.00 23.33  ? 115 CYS E C   1 
ATOM   10008 O  O   . CYS E 1 115 ? 21.049  -16.046 40.875  1.00 22.81  ? 115 CYS E O   1 
ATOM   10009 C  CB  . CYS E 1 115 ? 19.048  -14.670 38.631  1.00 21.90  ? 115 CYS E CB  1 
ATOM   10010 S  SG  . CYS E 1 115 ? 18.195  -13.129 38.230  1.00 23.21  ? 115 CYS E SG  1 
ATOM   10011 N  N   . PHE E 1 116 ? 21.518  -16.484 38.715  1.00 23.49  ? 116 PHE E N   1 
ATOM   10012 C  CA  . PHE E 1 116 ? 22.020  -17.810 39.009  1.00 22.96  ? 116 PHE E CA  1 
ATOM   10013 C  C   . PHE E 1 116 ? 23.302  -17.734 39.842  1.00 22.88  ? 116 PHE E C   1 
ATOM   10014 O  O   . PHE E 1 116 ? 23.563  -18.556 40.697  1.00 23.50  ? 116 PHE E O   1 
ATOM   10015 C  CB  . PHE E 1 116 ? 22.199  -18.543 37.683  1.00 22.79  ? 116 PHE E CB  1 
ATOM   10016 C  CG  . PHE E 1 116 ? 22.500  -20.017 37.876  1.00 24.92  ? 116 PHE E CG  1 
ATOM   10017 C  CD1 . PHE E 1 116 ? 21.467  -20.937 37.974  1.00 27.78  ? 116 PHE E CD1 1 
ATOM   10018 C  CD2 . PHE E 1 116 ? 23.810  -20.479 37.997  1.00 26.41  ? 116 PHE E CD2 1 
ATOM   10019 C  CE1 . PHE E 1 116 ? 21.738  -22.274 38.216  1.00 30.42  ? 116 PHE E CE1 1 
ATOM   10020 C  CE2 . PHE E 1 116 ? 24.069  -21.830 38.188  1.00 25.34  ? 116 PHE E CE2 1 
ATOM   10021 C  CZ  . PHE E 1 116 ? 23.047  -22.723 38.310  1.00 26.79  ? 116 PHE E CZ  1 
ATOM   10022 N  N   . ALA E 1 117 ? 24.119  -16.735 39.587  1.00 23.15  ? 117 ALA E N   1 
ATOM   10023 C  CA  . ALA E 1 117 ? 25.371  -16.589 40.306  1.00 23.96  ? 117 ALA E CA  1 
ATOM   10024 C  C   . ALA E 1 117 ? 25.085  -16.331 41.777  1.00 22.58  ? 117 ALA E C   1 
ATOM   10025 O  O   . ALA E 1 117 ? 25.694  -16.938 42.650  1.00 23.03  ? 117 ALA E O   1 
ATOM   10026 C  CB  . ALA E 1 117 ? 26.212  -15.488 39.694  1.00 22.60  ? 117 ALA E CB  1 
ATOM   10027 N  N   . LEU E 1 118 ? 24.132  -15.448 42.047  1.00 21.73  ? 118 LEU E N   1 
ATOM   10028 C  CA  . LEU E 1 118 ? 23.774  -15.149 43.427  1.00 23.28  ? 118 LEU E CA  1 
ATOM   10029 C  C   . LEU E 1 118 ? 23.097  -16.366 44.092  1.00 25.68  ? 118 LEU E C   1 
ATOM   10030 O  O   . LEU E 1 118 ? 23.391  -16.698 45.251  1.00 23.92  ? 118 LEU E O   1 
ATOM   10031 C  CB  . LEU E 1 118 ? 22.900  -13.902 43.473  1.00 21.63  ? 118 LEU E CB  1 
ATOM   10032 C  CG  . LEU E 1 118 ? 22.397  -13.496 44.850  1.00 23.16  ? 118 LEU E CG  1 
ATOM   10033 C  CD1 . LEU E 1 118 ? 23.575  -13.265 45.762  1.00 28.06  ? 118 LEU E CD1 1 
ATOM   10034 C  CD2 . LEU E 1 118 ? 21.562  -12.245 44.793  1.00 24.07  ? 118 LEU E CD2 1 
ATOM   10035 N  N   . ALA E 1 119 ? 22.185  -17.038 43.370  1.00 24.16  ? 119 ALA E N   1 
ATOM   10036 C  CA  . ALA E 1 119 ? 21.546  -18.226 43.920  1.00 24.79  ? 119 ALA E CA  1 
ATOM   10037 C  C   . ALA E 1 119 ? 22.587  -19.272 44.323  1.00 26.33  ? 119 ALA E C   1 
ATOM   10038 O  O   . ALA E 1 119 ? 22.451  -19.928 45.359  1.00 26.98  ? 119 ALA E O   1 
ATOM   10039 C  CB  . ALA E 1 119 ? 20.578  -18.800 42.902  1.00 23.57  ? 119 ALA E CB  1 
ATOM   10040 N  N   . THR E 1 120 ? 23.606  -19.442 43.461  1.00 24.17  ? 120 THR E N   1 
ATOM   10041 C  CA  . THR E 1 120 ? 24.654  -20.401 43.693  1.00 25.84  ? 120 THR E CA  1 
ATOM   10042 C  C   . THR E 1 120 ? 25.348  -20.070 45.002  1.00 25.77  ? 120 THR E C   1 
ATOM   10043 O  O   . THR E 1 120 ? 25.620  -20.980 45.789  1.00 22.97  ? 120 THR E O   1 
ATOM   10044 C  CB  . THR E 1 120 ? 25.656  -20.374 42.543  1.00 25.62  ? 120 THR E CB  1 
ATOM   10045 O  OG1 . THR E 1 120 ? 24.957  -20.951 41.459  1.00 25.19  ? 120 THR E OG1 1 
ATOM   10046 C  CG2 . THR E 1 120 ? 26.825  -21.306 42.757  1.00 27.41  ? 120 THR E CG2 1 
ATOM   10047 N  N   . GLU E 1 121 ? 25.683  -18.793 45.192  1.00 25.32  ? 121 GLU E N   1 
ATOM   10048 C  CA  . GLU E 1 121 ? 26.397  -18.397 46.400  1.00 31.56  ? 121 GLU E CA  1 
ATOM   10049 C  C   . GLU E 1 121 ? 25.518  -18.657 47.627  1.00 28.14  ? 121 GLU E C   1 
ATOM   10050 O  O   . GLU E 1 121 ? 25.990  -19.127 48.644  1.00 26.46  ? 121 GLU E O   1 
ATOM   10051 C  CB  . GLU E 1 121 ? 26.821  -16.923 46.440  1.00 35.93  ? 121 GLU E CB  1 
ATOM   10052 C  CG  . GLU E 1 121 ? 27.972  -16.592 45.484  1.00 36.57  ? 121 GLU E CG  1 
ATOM   10053 C  CD  . GLU E 1 121 ? 29.321  -17.106 45.882  1.00 34.10  ? 121 GLU E CD  1 
ATOM   10054 O  OE1 . GLU E 1 121 ? 29.493  -17.416 47.082  1.00 40.23  ? 121 GLU E OE1 1 
ATOM   10055 O  OE2 . GLU E 1 121 ? 30.143  -17.240 44.977  1.00 34.49  ? 121 GLU E OE2 1 
ATOM   10056 N  N   . ILE E 1 122 ? 24.239  -18.294 47.559  1.00 26.23  ? 122 ILE E N   1 
ATOM   10057 C  CA  . ILE E 1 122 ? 23.378  -18.451 48.715  1.00 25.48  ? 122 ILE E CA  1 
ATOM   10058 C  C   . ILE E 1 122 ? 23.251  -19.945 49.033  1.00 25.30  ? 122 ILE E C   1 
ATOM   10059 O  O   . ILE E 1 122 ? 23.510  -20.348 50.159  1.00 29.02  ? 122 ILE E O   1 
ATOM   10060 C  CB  . ILE E 1 122 ? 22.034  -17.770 48.461  1.00 24.94  ? 122 ILE E CB  1 
ATOM   10061 C  CG1 . ILE E 1 122 ? 22.166  -16.258 48.475  1.00 24.19  ? 122 ILE E CG1 1 
ATOM   10062 C  CG2 . ILE E 1 122 ? 20.992  -18.237 49.474  1.00 28.74  ? 122 ILE E CG2 1 
ATOM   10063 C  CD1 . ILE E 1 122 ? 20.960  -15.545 47.884  1.00 23.07  ? 122 ILE E CD1 1 
ATOM   10064 N  N   . MET E 1 123 ? 22.883  -20.789 48.065  1.00 25.90  ? 123 MET E N   1 
ATOM   10065 C  CA  . MET E 1 123 ? 22.685  -22.205 48.358  1.00 29.18  ? 123 MET E CA  1 
ATOM   10066 C  C   . MET E 1 123 ? 23.974  -22.908 48.762  1.00 32.54  ? 123 MET E C   1 
ATOM   10067 O  O   . MET E 1 123 ? 23.923  -23.953 49.402  1.00 35.50  ? 123 MET E O   1 
ATOM   10068 C  CB  . MET E 1 123 ? 22.105  -22.935 47.150  1.00 31.91  ? 123 MET E CB  1 
ATOM   10069 C  CG  . MET E 1 123 ? 20.633  -22.660 46.999  1.00 41.49  ? 123 MET E CG  1 
ATOM   10070 S  SD  . MET E 1 123 ? 19.602  -23.374 48.306  1.00 40.73  ? 123 MET E SD  1 
ATOM   10071 C  CE  . MET E 1 123 ? 20.289  -25.027 48.401  1.00 37.28  ? 123 MET E CE  1 
ATOM   10072 N  N   . GLY E 1 124 ? 25.122  -22.367 48.323  1.00 36.95  ? 124 GLY E N   1 
ATOM   10073 C  CA  . GLY E 1 124 ? 26.438  -22.859 48.711  1.00 34.18  ? 124 GLY E CA  1 
ATOM   10074 C  C   . GLY E 1 124 ? 26.641  -22.750 50.217  1.00 31.79  ? 124 GLY E C   1 
ATOM   10075 O  O   . GLY E 1 124 ? 27.143  -23.689 50.813  1.00 35.69  ? 124 GLY E O   1 
ATOM   10076 N  N   . ARG E 1 125 ? 26.183  -21.653 50.815  1.00 30.81  ? 125 ARG E N   1 
ATOM   10077 C  CA  . ARG E 1 125 ? 26.309  -21.420 52.241  1.00 34.55  ? 125 ARG E CA  1 
ATOM   10078 C  C   . ARG E 1 125 ? 25.270  -22.210 53.033  1.00 32.81  ? 125 ARG E C   1 
ATOM   10079 O  O   . ARG E 1 125 ? 25.403  -22.385 54.224  1.00 34.35  ? 125 ARG E O   1 
ATOM   10080 C  CB  . ARG E 1 125 ? 26.082  -19.940 52.575  1.00 38.46  ? 125 ARG E CB  1 
ATOM   10081 C  CG  . ARG E 1 125 ? 26.643  -18.864 51.657  1.00 48.79  ? 125 ARG E CG  1 
ATOM   10082 C  CD  . ARG E 1 125 ? 28.140  -18.650 51.554  1.00 54.84  ? 125 ARG E CD  1 
ATOM   10083 N  NE  . ARG E 1 125 ? 28.332  -18.195 52.933  1.00 57.19  ? 125 ARG E NE  1 
ATOM   10084 C  CZ  . ARG E 1 125 ? 28.605  -16.956 53.232  1.00 57.73  ? 125 ARG E CZ  1 
ATOM   10085 N  NH1 . ARG E 1 125 ? 29.363  -16.267 52.358  1.00 54.02  ? 125 ARG E NH1 1 
ATOM   10086 N  NH2 . ARG E 1 125 ? 28.166  -16.507 54.416  1.00 46.28  ? 125 ARG E NH2 1 
ATOM   10087 N  N   . LEU E 1 126 ? 24.219  -22.681 52.376  1.00 30.95  ? 126 LEU E N   1 
ATOM   10088 C  CA  . LEU E 1 126 ? 23.128  -23.338 53.070  1.00 27.19  ? 126 LEU E CA  1 
ATOM   10089 C  C   . LEU E 1 126 ? 23.195  -24.844 52.877  1.00 28.71  ? 126 LEU E C   1 
ATOM   10090 O  O   . LEU E 1 126 ? 22.362  -25.494 53.468  1.00 29.62  ? 126 LEU E O   1 
ATOM   10091 C  CB  . LEU E 1 126 ? 21.778  -22.793 52.593  1.00 26.16  ? 126 LEU E CB  1 
ATOM   10092 C  CG  . LEU E 1 126 ? 21.473  -21.323 52.914  1.00 27.56  ? 126 LEU E CG  1 
ATOM   10093 C  CD1 . LEU E 1 126 ? 20.121  -20.933 52.365  1.00 30.53  ? 126 LEU E CD1 1 
ATOM   10094 C  CD2 . LEU E 1 126 ? 21.499  -21.007 54.388  1.00 30.48  ? 126 LEU E CD2 1 
ATOM   10095 N  N   . ARG E 1 127 ? 24.102  -25.370 52.026  1.00 34.17  ? 127 ARG E N   1 
ATOM   10096 C  CA  . ARG E 1 127 ? 24.242  -26.807 51.794  1.00 37.47  ? 127 ARG E CA  1 
ATOM   10097 C  C   . ARG E 1 127 ? 24.266  -27.502 53.157  1.00 35.29  ? 127 ARG E C   1 
ATOM   10098 O  O   . ARG E 1 127 ? 24.950  -27.086 54.080  1.00 33.00  ? 127 ARG E O   1 
ATOM   10099 C  CB  . ARG E 1 127 ? 25.517  -27.259 51.066  1.00 44.56  ? 127 ARG E CB  1 
ATOM   10100 C  CG  . ARG E 1 127 ? 25.643  -27.200 49.547  1.00 64.89  ? 127 ARG E CG  1 
ATOM   10101 C  CD  . ARG E 1 127 ? 24.542  -27.918 48.755  1.00 77.18  ? 127 ARG E CD  1 
ATOM   10102 N  NE  . ARG E 1 127 ? 24.311  -27.297 47.437  1.00 87.33  ? 127 ARG E NE  1 
ATOM   10103 C  CZ  . ARG E 1 127 ? 23.146  -26.834 46.925  1.00 89.00  ? 127 ARG E CZ  1 
ATOM   10104 N  NH1 . ARG E 1 127 ? 21.995  -27.072 47.534  1.00 98.16  ? 127 ARG E NH1 1 
ATOM   10105 N  NH2 . ARG E 1 127 ? 23.114  -26.216 45.747  1.00 71.30  ? 127 ARG E NH2 1 
ATOM   10106 N  N   . GLY E 1 128 ? 23.436  -28.525 53.337  1.00 36.82  ? 128 GLY E N   1 
ATOM   10107 C  CA  . GLY E 1 128 ? 23.434  -29.261 54.591  1.00 32.62  ? 128 GLY E CA  1 
ATOM   10108 C  C   . GLY E 1 128 ? 22.395  -28.738 55.573  1.00 31.55  ? 128 GLY E C   1 
ATOM   10109 O  O   . GLY E 1 128 ? 21.977  -29.483 56.434  1.00 36.88  ? 128 GLY E O   1 
ATOM   10110 N  N   . ALA E 1 129 ? 21.944  -27.486 55.460  1.00 27.15  ? 129 ALA E N   1 
ATOM   10111 C  CA  . ALA E 1 129 ? 21.018  -26.932 56.429  1.00 25.98  ? 129 ALA E CA  1 
ATOM   10112 C  C   . ALA E 1 129 ? 19.570  -26.894 55.940  1.00 26.85  ? 129 ALA E C   1 
ATOM   10113 O  O   . ALA E 1 129 ? 18.684  -26.694 56.772  1.00 24.52  ? 129 ALA E O   1 
ATOM   10114 C  CB  . ALA E 1 129 ? 21.444  -25.539 56.841  1.00 26.42  ? 129 ALA E CB  1 
ATOM   10115 N  N   . VAL E 1 130 ? 19.331  -26.988 54.624  1.00 28.54  ? 130 VAL E N   1 
ATOM   10116 C  CA  . VAL E 1 130 ? 18.007  -26.696 54.079  1.00 27.00  ? 130 VAL E CA  1 
ATOM   10117 C  C   . VAL E 1 130 ? 17.633  -27.752 53.046  1.00 26.47  ? 130 VAL E C   1 
ATOM   10118 O  O   . VAL E 1 130 ? 18.488  -28.471 52.587  1.00 23.44  ? 130 VAL E O   1 
ATOM   10119 C  CB  . VAL E 1 130 ? 17.905  -25.297 53.464  1.00 26.34  ? 130 VAL E CB  1 
ATOM   10120 C  CG1 . VAL E 1 130 ? 18.347  -24.200 54.430  1.00 28.02  ? 130 VAL E CG1 1 
ATOM   10121 C  CG2 . VAL E 1 130 ? 18.702  -25.195 52.189  1.00 27.11  ? 130 VAL E CG2 1 
ATOM   10122 N  N   . THR E 1 131 ? 16.343  -27.848 52.721  1.00 26.51  ? 131 THR E N   1 
ATOM   10123 C  CA  . THR E 1 131 ? 15.858  -28.751 51.688  1.00 26.51  ? 131 THR E CA  1 
ATOM   10124 C  C   . THR E 1 131 ? 15.096  -27.922 50.666  1.00 27.91  ? 131 THR E C   1 
ATOM   10125 O  O   . THR E 1 131 ? 14.208  -27.150 51.026  1.00 26.34  ? 131 THR E O   1 
ATOM   10126 C  CB  . THR E 1 131 ? 15.000  -29.859 52.299  1.00 27.14  ? 131 THR E CB  1 
ATOM   10127 O  OG1 . THR E 1 131 ? 15.879  -30.650 53.114  1.00 29.59  ? 131 THR E OG1 1 
ATOM   10128 C  CG2 . THR E 1 131 ? 14.350  -30.734 51.242  1.00 24.34  ? 131 THR E CG2 1 
ATOM   10129 N  N   . PRO E 1 132 ? 15.454  -27.995 49.363  1.00 32.14  ? 132 PRO E N   1 
ATOM   10130 C  CA  . PRO E 1 132 ? 14.797  -27.163 48.356  1.00 31.81  ? 132 PRO E CA  1 
ATOM   10131 C  C   . PRO E 1 132 ? 13.377  -27.657 48.188  1.00 25.55  ? 132 PRO E C   1 
ATOM   10132 O  O   . PRO E 1 132 ? 13.170  -28.845 48.099  1.00 25.30  ? 132 PRO E O   1 
ATOM   10133 C  CB  . PRO E 1 132 ? 15.642  -27.378 47.090  1.00 33.02  ? 132 PRO E CB  1 
ATOM   10134 C  CG  . PRO E 1 132 ? 16.919  -27.981 47.617  1.00 33.76  ? 132 PRO E CG  1 
ATOM   10135 C  CD  . PRO E 1 132 ? 16.490  -28.857 48.776  1.00 30.76  ? 132 PRO E CD  1 
ATOM   10136 N  N   . GLN E 1 133 ? 12.420  -26.744 48.190  1.00 24.64  ? 133 GLN E N   1 
ATOM   10137 C  CA  . GLN E 1 133 ? 11.041  -27.076 47.874  1.00 26.15  ? 133 GLN E CA  1 
ATOM   10138 C  C   . GLN E 1 133 ? 10.607  -26.599 46.490  1.00 24.91  ? 133 GLN E C   1 
ATOM   10139 O  O   . GLN E 1 133 ? 9.721   -27.189 45.936  1.00 27.37  ? 133 GLN E O   1 
ATOM   10140 C  CB  . GLN E 1 133 ? 10.058  -26.333 48.766  1.00 26.59  ? 133 GLN E CB  1 
ATOM   10141 C  CG  . GLN E 1 133 ? 10.187  -26.684 50.244  1.00 31.72  ? 133 GLN E CG  1 
ATOM   10142 C  CD  . GLN E 1 133 ? 9.965   -28.158 50.497  1.00 27.72  ? 133 GLN E CD  1 
ATOM   10143 O  OE1 . GLN E 1 133 ? 9.155   -28.825 49.852  1.00 25.36  ? 133 GLN E OE1 1 
ATOM   10144 N  NE2 . GLN E 1 133 ? 10.838  -28.704 51.310  1.00 28.01  ? 133 GLN E NE2 1 
ATOM   10145 N  N   . ASP E 1 134 ? 11.101  -25.466 46.003  1.00 24.93  ? 134 ASP E N   1 
ATOM   10146 C  CA  . ASP E 1 134 ? 10.785  -24.969 44.673  1.00 27.08  ? 134 ASP E CA  1 
ATOM   10147 C  C   . ASP E 1 134 ? 11.967  -24.156 44.134  1.00 24.40  ? 134 ASP E C   1 
ATOM   10148 O  O   . ASP E 1 134 ? 12.621  -23.440 44.889  1.00 25.19  ? 134 ASP E O   1 
ATOM   10149 C  CB  . ASP E 1 134 ? 9.494   -24.160 44.713  1.00 27.93  ? 134 ASP E CB  1 
ATOM   10150 C  CG  . ASP E 1 134 ? 8.698   -24.101 43.420  1.00 26.50  ? 134 ASP E CG  1 
ATOM   10151 O  OD1 . ASP E 1 134 ? 9.012   -24.919 42.518  1.00 25.80  ? 134 ASP E OD1 1 
ATOM   10152 O  OD2 . ASP E 1 134 ? 7.735   -23.291 43.384  1.00 29.40  ? 134 ASP E OD2 1 
ATOM   10153 N  N   . GLU E 1 135 ? 12.253  -24.313 42.845  1.00 24.14  ? 135 GLU E N   1 
ATOM   10154 C  CA  . GLU E 1 135 ? 13.199  -23.476 42.133  1.00 22.30  ? 135 GLU E CA  1 
ATOM   10155 C  C   . GLU E 1 135 ? 12.610  -23.153 40.768  1.00 19.73  ? 135 GLU E C   1 
ATOM   10156 O  O   . GLU E 1 135 ? 12.286  -24.039 40.019  1.00 19.02  ? 135 GLU E O   1 
ATOM   10157 C  CB  . GLU E 1 135 ? 14.531  -24.190 41.974  1.00 23.84  ? 135 GLU E CB  1 
ATOM   10158 C  CG  . GLU E 1 135 ? 15.562  -23.333 41.238  1.00 26.25  ? 135 GLU E CG  1 
ATOM   10159 C  CD  . GLU E 1 135 ? 16.885  -24.047 41.060  1.00 30.58  ? 135 GLU E CD  1 
ATOM   10160 O  OE1 . GLU E 1 135 ? 17.027  -25.118 41.712  1.00 29.22  ? 135 GLU E OE1 1 
ATOM   10161 O  OE2 . GLU E 1 135 ? 17.762  -23.581 40.307  1.00 30.41  ? 135 GLU E OE2 1 
ATOM   10162 N  N   . VAL E 1 136 ? 12.391  -21.880 40.481  1.00 20.81  ? 136 VAL E N   1 
ATOM   10163 C  CA  . VAL E 1 136 ? 11.802  -21.445 39.230  1.00 20.18  ? 136 VAL E CA  1 
ATOM   10164 C  C   . VAL E 1 136 ? 12.699  -20.364 38.616  1.00 18.04  ? 136 VAL E C   1 
ATOM   10165 O  O   . VAL E 1 136 ? 13.125  -19.435 39.283  1.00 18.23  ? 136 VAL E O   1 
ATOM   10166 C  CB  . VAL E 1 136 ? 10.366  -20.930 39.481  1.00 22.58  ? 136 VAL E CB  1 
ATOM   10167 C  CG1 . VAL E 1 136 ? 9.737   -20.333 38.223  1.00 23.60  ? 136 VAL E CG1 1 
ATOM   10168 C  CG2 . VAL E 1 136 ? 9.457   -22.025 39.982  1.00 24.31  ? 136 VAL E CG2 1 
ATOM   10169 N  N   . HIS E 1 137 ? 12.983  -20.520 37.336  1.00 19.43  ? 137 HIS E N   1 
ATOM   10170 C  CA  . HIS E 1 137 ? 13.727  -19.580 36.519  1.00 22.90  ? 137 HIS E CA  1 
ATOM   10171 C  C   . HIS E 1 137 ? 12.707  -18.910 35.624  1.00 20.75  ? 137 HIS E C   1 
ATOM   10172 O  O   . HIS E 1 137 ? 12.097  -19.566 34.805  1.00 25.19  ? 137 HIS E O   1 
ATOM   10173 C  CB  . HIS E 1 137 ? 14.793  -20.312 35.679  1.00 24.28  ? 137 HIS E CB  1 
ATOM   10174 C  CG  . HIS E 1 137 ? 15.836  -20.994 36.502  1.00 28.13  ? 137 HIS E CG  1 
ATOM   10175 N  ND1 . HIS E 1 137 ? 16.933  -21.567 35.918  1.00 28.23  ? 137 HIS E ND1 1 
ATOM   10176 C  CD2 . HIS E 1 137 ? 15.939  -21.241 37.827  1.00 30.13  ? 137 HIS E CD2 1 
ATOM   10177 C  CE1 . HIS E 1 137 ? 17.676  -22.126 36.867  1.00 28.75  ? 137 HIS E CE1 1 
ATOM   10178 N  NE2 . HIS E 1 137 ? 17.098  -21.933 38.047  1.00 26.61  ? 137 HIS E NE2 1 
ATOM   10179 N  N   . GLY E 1 138 ? 12.478  -17.625 35.872  1.00 21.75  ? 138 GLY E N   1 
ATOM   10180 C  CA  . GLY E 1 138 ? 11.435  -16.889 35.202  1.00 22.02  ? 138 GLY E CA  1 
ATOM   10181 C  C   . GLY E 1 138 ? 12.030  -15.976 34.139  1.00 24.35  ? 138 GLY E C   1 
ATOM   10182 O  O   . GLY E 1 138 ? 13.162  -15.550 34.287  1.00 26.96  ? 138 GLY E O   1 
ATOM   10183 N  N   . PHE E 1 139 ? 11.251  -15.672 33.099  1.00 22.04  ? 139 PHE E N   1 
ATOM   10184 C  CA  . PHE E 1 139 ? 11.661  -14.754 32.058  1.00 23.05  ? 139 PHE E CA  1 
ATOM   10185 C  C   . PHE E 1 139 ? 10.471  -13.940 31.580  1.00 24.76  ? 139 PHE E C   1 
ATOM   10186 O  O   . PHE E 1 139 ? 9.421   -14.502 31.325  1.00 25.93  ? 139 PHE E O   1 
ATOM   10187 C  CB  . PHE E 1 139 ? 12.248  -15.579 30.919  1.00 24.47  ? 139 PHE E CB  1 
ATOM   10188 C  CG  . PHE E 1 139 ? 11.435  -16.782 30.471  1.00 27.87  ? 139 PHE E CG  1 
ATOM   10189 C  CD1 . PHE E 1 139 ? 10.367  -16.644 29.589  1.00 29.77  ? 139 PHE E CD1 1 
ATOM   10190 C  CD2 . PHE E 1 139 ? 11.773  -18.060 30.909  1.00 30.05  ? 139 PHE E CD2 1 
ATOM   10191 C  CE1 . PHE E 1 139 ? 9.626   -17.751 29.181  1.00 29.24  ? 139 PHE E CE1 1 
ATOM   10192 C  CE2 . PHE E 1 139 ? 11.062  -19.171 30.460  1.00 33.26  ? 139 PHE E CE2 1 
ATOM   10193 C  CZ  . PHE E 1 139 ? 9.983   -19.009 29.591  1.00 31.75  ? 139 PHE E CZ  1 
ATOM   10194 N  N   . LYS E 1 140 ? 10.632  -12.620 31.466  1.00 29.79  ? 140 LYS E N   1 
ATOM   10195 C  CA  . LYS E 1 140 ? 9.567   -11.744 30.993  1.00 34.58  ? 140 LYS E CA  1 
ATOM   10196 C  C   . LYS E 1 140 ? 9.575   -11.821 29.475  1.00 32.96  ? 140 LYS E C   1 
ATOM   10197 O  O   . LYS E 1 140 ? 10.622  -11.999 28.897  1.00 29.73  ? 140 LYS E O   1 
ATOM   10198 C  CB  . LYS E 1 140 ? 9.728   -10.335 31.582  1.00 37.91  ? 140 LYS E CB  1 
ATOM   10199 C  CG  . LYS E 1 140 ? 8.430   -9.553  31.923  1.00 49.24  ? 140 LYS E CG  1 
ATOM   10200 C  CD  . LYS E 1 140 ? 7.382   -10.218 32.834  1.00 59.62  ? 140 LYS E CD  1 
ATOM   10201 C  CE  . LYS E 1 140 ? 5.939   -9.776  32.637  1.00 56.57  ? 140 LYS E CE  1 
ATOM   10202 N  NZ  . LYS E 1 140 ? 5.697   -8.523  33.362  1.00 56.15  ? 140 LYS E NZ  1 
ATOM   10203 N  N   . TYR E 1 141 ? 8.405   -11.780 28.842  1.00 35.01  ? 141 TYR E N   1 
ATOM   10204 C  CA  . TYR E 1 141 ? 8.295   -11.693 27.387  1.00 35.56  ? 141 TYR E CA  1 
ATOM   10205 C  C   . TYR E 1 141 ? 8.600   -10.271 26.957  1.00 38.41  ? 141 TYR E C   1 
ATOM   10206 O  O   . TYR E 1 141 ? 8.625   -9.377  27.788  1.00 34.20  ? 141 TYR E O   1 
ATOM   10207 C  CB  . TYR E 1 141 ? 6.915   -12.078 26.869  1.00 32.84  ? 141 TYR E CB  1 
ATOM   10208 C  CG  . TYR E 1 141 ? 6.773   -13.577 26.707  1.00 35.64  ? 141 TYR E CG  1 
ATOM   10209 C  CD1 . TYR E 1 141 ? 6.420   -14.355 27.776  1.00 38.90  ? 141 TYR E CD1 1 
ATOM   10210 C  CD2 . TYR E 1 141 ? 6.987   -14.206 25.491  1.00 43.46  ? 141 TYR E CD2 1 
ATOM   10211 C  CE1 . TYR E 1 141 ? 6.275   -15.723 27.650  1.00 43.73  ? 141 TYR E CE1 1 
ATOM   10212 C  CE2 . TYR E 1 141 ? 6.834   -15.569 25.341  1.00 40.16  ? 141 TYR E CE2 1 
ATOM   10213 C  CZ  . TYR E 1 141 ? 6.491   -16.325 26.434  1.00 40.79  ? 141 TYR E CZ  1 
ATOM   10214 O  OH  . TYR E 1 141 ? 6.350   -17.666 26.374  1.00 51.62  ? 141 TYR E OH  1 
ATOM   10215 N  N   . PHE E 1 142 ? 8.866   -10.055 25.667  1.00 46.33  ? 142 PHE E N   1 
ATOM   10216 C  CA  . PHE E 1 142 ? 9.631   -8.873  25.333  1.00 48.75  ? 142 PHE E CA  1 
ATOM   10217 C  C   . PHE E 1 142 ? 8.760   -7.613  25.473  1.00 50.97  ? 142 PHE E C   1 
ATOM   10218 O  O   . PHE E 1 142 ? 9.351   -6.528  25.610  1.00 47.01  ? 142 PHE E O   1 
ATOM   10219 C  CB  . PHE E 1 142 ? 10.434  -9.093  24.041  1.00 54.03  ? 142 PHE E CB  1 
ATOM   10220 C  CG  . PHE E 1 142 ? 9.734   -8.653  22.771  1.00 66.10  ? 142 PHE E CG  1 
ATOM   10221 C  CD1 . PHE E 1 142 ? 8.836   -9.506  22.130  1.00 77.15  ? 142 PHE E CD1 1 
ATOM   10222 C  CD2 . PHE E 1 142 ? 9.946   -7.371  22.252  1.00 68.59  ? 142 PHE E CD2 1 
ATOM   10223 C  CE1 . PHE E 1 142 ? 8.162   -9.076  20.989  1.00 85.70  ? 142 PHE E CE1 1 
ATOM   10224 C  CE2 . PHE E 1 142 ? 9.293   -6.951  21.098  1.00 72.90  ? 142 PHE E CE2 1 
ATOM   10225 C  CZ  . PHE E 1 142 ? 8.402   -7.804  20.468  1.00 85.65  ? 142 PHE E CZ  1 
ATOM   10226 N  N   . ASP E 1 143 ? 7.406   -7.704  25.510  1.00 45.19  ? 143 ASP E N   1 
ATOM   10227 C  CA  . ASP E 1 143 ? 6.647   -6.467  25.753  1.00 45.13  ? 143 ASP E CA  1 
ATOM   10228 C  C   . ASP E 1 143 ? 5.835   -6.541  27.036  1.00 41.16  ? 143 ASP E C   1 
ATOM   10229 O  O   . ASP E 1 143 ? 4.671   -6.181  27.049  1.00 42.58  ? 143 ASP E O   1 
ATOM   10230 C  CB  . ASP E 1 143 ? 5.771   -6.036  24.595  1.00 44.79  ? 143 ASP E CB  1 
ATOM   10231 C  CG  . ASP E 1 143 ? 5.112   -7.214  23.890  1.00 55.61  ? 143 ASP E CG  1 
ATOM   10232 O  OD1 . ASP E 1 143 ? 5.571   -8.429  24.094  1.00 43.87  ? 143 ASP E OD1 1 
ATOM   10233 O  OD2 . ASP E 1 143 ? 4.128   -6.907  23.169  1.00 58.70  ? 143 ASP E OD2 1 
ATOM   10234 N  N   . GLU E 1 144 ? 6.488   -6.967  28.103  1.00 38.61  ? 144 GLU E N   1 
ATOM   10235 C  CA  . GLU E 1 144 ? 5.900   -7.150  29.421  1.00 39.16  ? 144 GLU E CA  1 
ATOM   10236 C  C   . GLU E 1 144 ? 4.690   -8.081  29.406  1.00 36.98  ? 144 GLU E C   1 
ATOM   10237 O  O   . GLU E 1 144 ? 3.885   -8.024  30.344  1.00 42.62  ? 144 GLU E O   1 
ATOM   10238 C  CB  . GLU E 1 144 ? 5.605   -5.778  30.026  1.00 37.07  ? 144 GLU E CB  1 
ATOM   10239 C  CG  . GLU E 1 144 ? 6.862   -4.959  30.242  1.00 35.74  ? 144 GLU E CG  1 
ATOM   10240 C  CD  . GLU E 1 144 ? 7.773   -5.557  31.299  1.00 39.97  ? 144 GLU E CD  1 
ATOM   10241 O  OE1 . GLU E 1 144 ? 7.309   -6.104  32.326  1.00 46.51  ? 144 GLU E OE1 1 
ATOM   10242 O  OE2 . GLU E 1 144 ? 8.995   -5.462  31.077  1.00 49.54  ? 144 GLU E OE2 1 
ATOM   10243 N  N   . ARG E 1 145 ? 4.612   -8.977  28.409  1.00 29.81  ? 145 ARG E N   1 
ATOM   10244 C  CA  . ARG E 1 145 ? 3.512   -9.921  28.382  1.00 29.29  ? 145 ARG E CA  1 
ATOM   10245 C  C   . ARG E 1 145 ? 3.797   -11.177 29.212  1.00 33.59  ? 145 ARG E C   1 
ATOM   10246 O  O   . ARG E 1 145 ? 4.939   -11.520 29.545  1.00 34.07  ? 145 ARG E O   1 
ATOM   10247 C  CB  . ARG E 1 145 ? 3.150   -10.286 26.950  1.00 30.88  ? 145 ARG E CB  1 
ATOM   10248 C  CG  . ARG E 1 145 ? 2.685   -9.030  26.241  1.00 30.50  ? 145 ARG E CG  1 
ATOM   10249 C  CD  . ARG E 1 145 ? 2.030   -9.349  24.933  1.00 31.18  ? 145 ARG E CD  1 
ATOM   10250 N  NE  . ARG E 1 145 ? 1.713   -8.100  24.230  1.00 32.91  ? 145 ARG E NE  1 
ATOM   10251 C  CZ  . ARG E 1 145 ? 0.548   -7.469  24.186  1.00 36.11  ? 145 ARG E CZ  1 
ATOM   10252 N  NH1 . ARG E 1 145 ? -0.543  -7.998  24.736  1.00 37.37  ? 145 ARG E NH1 1 
ATOM   10253 N  NH2 . ARG E 1 145 ? 0.492   -6.267  23.619  1.00 34.19  ? 145 ARG E NH2 1 
ATOM   10254 N  N   . ASP E 1 146 ? 2.706   -11.835 29.601  1.00 31.20  ? 146 ASP E N   1 
ATOM   10255 C  CA  . ASP E 1 146 ? 2.821   -13.026 30.425  1.00 30.71  ? 146 ASP E CA  1 
ATOM   10256 C  C   . ASP E 1 146 ? 2.485   -14.199 29.533  1.00 26.99  ? 146 ASP E C   1 
ATOM   10257 O  O   . ASP E 1 146 ? 2.343   -14.032 28.322  1.00 23.10  ? 146 ASP E O   1 
ATOM   10258 C  CB  . ASP E 1 146 ? 1.968   -12.963 31.689  1.00 33.01  ? 146 ASP E CB  1 
ATOM   10259 C  CG  . ASP E 1 146 ? 0.487   -12.754 31.401  1.00 30.49  ? 146 ASP E CG  1 
ATOM   10260 O  OD1 . ASP E 1 146 ? 0.057   -13.110 30.308  1.00 25.92  ? 146 ASP E OD1 1 
ATOM   10261 O  OD2 . ASP E 1 146 ? -0.195  -12.149 32.233  1.00 34.97  ? 146 ASP E OD2 1 
ATOM   10262 N  N   . MET E 1 147 ? 2.321   -15.364 30.165  1.00 25.38  ? 147 MET E N   1 
ATOM   10263 C  CA  . MET E 1 147 ? 2.141   -16.580 29.417  1.00 28.78  ? 147 MET E CA  1 
ATOM   10264 C  C   . MET E 1 147 ? 0.795   -16.611 28.687  1.00 25.16  ? 147 MET E C   1 
ATOM   10265 O  O   . MET E 1 147 ? 0.642   -17.353 27.747  1.00 23.65  ? 147 MET E O   1 
ATOM   10266 C  CB  . MET E 1 147 ? 2.336   -17.736 30.392  1.00 33.30  ? 147 MET E CB  1 
ATOM   10267 C  CG  . MET E 1 147 ? 2.507   -19.096 29.755  1.00 35.87  ? 147 MET E CG  1 
ATOM   10268 S  SD  . MET E 1 147 ? 4.004   -19.078 28.777  1.00 37.02  ? 147 MET E SD  1 
ATOM   10269 C  CE  . MET E 1 147 ? 5.367   -19.621 29.818  1.00 42.94  ? 147 MET E CE  1 
ATOM   10270 N  N   . LEU E 1 148 ? -0.173  -15.803 29.092  1.00 26.47  ? 148 LEU E N   1 
ATOM   10271 C  CA  . LEU E 1 148 ? -1.479  -15.749 28.448  1.00 27.55  ? 148 LEU E CA  1 
ATOM   10272 C  C   . LEU E 1 148 ? -1.481  -14.705 27.352  1.00 24.20  ? 148 LEU E C   1 
ATOM   10273 O  O   . LEU E 1 148 ? -2.513  -14.482 26.750  1.00 31.20  ? 148 LEU E O   1 
ATOM   10274 C  CB  . LEU E 1 148 ? -2.576  -15.403 29.459  1.00 26.89  ? 148 LEU E CB  1 
ATOM   10275 C  CG  . LEU E 1 148 ? -2.697  -16.375 30.639  1.00 28.65  ? 148 LEU E CG  1 
ATOM   10276 C  CD1 . LEU E 1 148 ? -3.696  -15.865 31.646  1.00 29.17  ? 148 LEU E CD1 1 
ATOM   10277 C  CD2 . LEU E 1 148 ? -3.026  -17.789 30.197  1.00 26.35  ? 148 LEU E CD2 1 
ATOM   10278 N  N   . GLY E 1 149 ? -0.366  -14.010 27.143  1.00 23.85  ? 149 GLY E N   1 
ATOM   10279 C  CA  . GLY E 1 149 ? -0.288  -13.087 26.026  1.00 21.35  ? 149 GLY E CA  1 
ATOM   10280 C  C   . GLY E 1 149 ? -0.770  -11.676 26.362  1.00 24.32  ? 149 GLY E C   1 
ATOM   10281 O  O   . GLY E 1 149 ? -0.835  -10.849 25.483  1.00 23.87  ? 149 GLY E O   1 
ATOM   10282 N  N   . PHE E 1 150 ? -1.077  -11.377 27.626  1.00 29.99  ? 150 PHE E N   1 
ATOM   10283 C  CA  . PHE E 1 150 ? -1.533  -10.054 28.058  1.00 27.71  ? 150 PHE E CA  1 
ATOM   10284 C  C   . PHE E 1 150 ? -0.388  -9.333  28.759  1.00 26.07  ? 150 PHE E C   1 
ATOM   10285 O  O   . PHE E 1 150 ? 0.455   -9.932  29.430  1.00 23.02  ? 150 PHE E O   1 
ATOM   10286 C  CB  . PHE E 1 150 ? -2.719  -10.130 29.028  1.00 27.43  ? 150 PHE E CB  1 
ATOM   10287 C  CG  . PHE E 1 150 ? -4.032  -10.345 28.313  1.00 26.63  ? 150 PHE E CG  1 
ATOM   10288 C  CD1 . PHE E 1 150 ? -4.311  -11.555 27.685  1.00 29.32  ? 150 PHE E CD1 1 
ATOM   10289 C  CD2 . PHE E 1 150 ? -4.976  -9.331  28.249  1.00 25.90  ? 150 PHE E CD2 1 
ATOM   10290 C  CE1 . PHE E 1 150 ? -5.497  -11.720 26.977  1.00 28.19  ? 150 PHE E CE1 1 
ATOM   10291 C  CE2 . PHE E 1 150 ? -6.156  -9.514  27.538  1.00 25.18  ? 150 PHE E CE2 1 
ATOM   10292 C  CZ  . PHE E 1 150 ? -6.414  -10.700 26.901  1.00 24.76  ? 150 PHE E CZ  1 
ATOM   10293 N  N   . VAL E 1 151 ? -0.397  -8.006  28.621  1.00 25.66  ? 151 VAL E N   1 
ATOM   10294 C  CA  . VAL E 1 151 ? 0.528   -7.198  29.373  1.00 24.99  ? 151 VAL E CA  1 
ATOM   10295 C  C   . VAL E 1 151 ? 0.173   -7.332  30.850  1.00 26.27  ? 151 VAL E C   1 
ATOM   10296 O  O   . VAL E 1 151 ? -0.998  -7.235  31.224  1.00 28.22  ? 151 VAL E O   1 
ATOM   10297 C  CB  . VAL E 1 151 ? 0.462   -5.732  28.910  1.00 24.02  ? 151 VAL E CB  1 
ATOM   10298 C  CG1 . VAL E 1 151 ? 1.477   -4.889  29.655  1.00 23.74  ? 151 VAL E CG1 1 
ATOM   10299 C  CG2 . VAL E 1 151 ? 0.625   -5.603  27.404  1.00 23.46  ? 151 VAL E CG2 1 
ATOM   10300 N  N   . ASP E 1 152 ? 1.217   -7.500  31.658  1.00 30.28  ? 152 ASP E N   1 
ATOM   10301 C  CA  . ASP E 1 152 ? 1.126   -7.913  33.056  1.00 29.91  ? 152 ASP E CA  1 
ATOM   10302 C  C   . ASP E 1 152 ? 2.025   -6.996  33.879  1.00 24.51  ? 152 ASP E C   1 
ATOM   10303 O  O   . ASP E 1 152 ? 3.242   -6.999  33.725  1.00 23.71  ? 152 ASP E O   1 
ATOM   10304 C  CB  . ASP E 1 152 ? 1.572   -9.359  33.183  1.00 30.11  ? 152 ASP E CB  1 
ATOM   10305 C  CG  . ASP E 1 152 ? 1.291   -10.069 34.494  1.00 31.86  ? 152 ASP E CG  1 
ATOM   10306 O  OD1 . ASP E 1 152 ? 1.493   -9.423  35.523  1.00 31.42  ? 152 ASP E OD1 1 
ATOM   10307 O  OD2 . ASP E 1 152 ? 0.953   -11.286 34.450  1.00 35.91  ? 152 ASP E OD2 1 
ATOM   10308 N  N   . GLY E 1 153 ? 1.414   -6.183  34.726  1.00 23.22  ? 153 GLY E N   1 
ATOM   10309 C  CA  . GLY E 1 153 ? 2.172   -5.227  35.529  1.00 26.04  ? 153 GLY E CA  1 
ATOM   10310 C  C   . GLY E 1 153 ? 1.578   -3.818  35.524  1.00 27.53  ? 153 GLY E C   1 
ATOM   10311 O  O   . GLY E 1 153 ? 1.912   -3.035  36.387  1.00 30.34  ? 153 GLY E O   1 
ATOM   10312 N  N   . THR E 1 154 ? 0.702   -3.513  34.560  1.00 29.49  ? 154 THR E N   1 
ATOM   10313 C  CA  . THR E 1 154 ? 0.309   -2.169  34.142  1.00 28.23  ? 154 THR E CA  1 
ATOM   10314 C  C   . THR E 1 154 ? -0.202  -1.328  35.303  1.00 27.53  ? 154 THR E C   1 
ATOM   10315 O  O   . THR E 1 154 ? 0.141   -0.165  35.439  1.00 26.72  ? 154 THR E O   1 
ATOM   10316 C  CB  . THR E 1 154 ? -0.815  -2.335  33.113  1.00 29.57  ? 154 THR E CB  1 
ATOM   10317 O  OG1 . THR E 1 154 ? -0.447  -3.318  32.143  1.00 27.31  ? 154 THR E OG1 1 
ATOM   10318 C  CG2 . THR E 1 154 ? -1.230  -1.009  32.513  1.00 28.85  ? 154 THR E CG2 1 
ATOM   10319 N  N   . GLU E 1 155 ? -1.099  -1.901  36.099  1.00 29.91  ? 155 GLU E N   1 
ATOM   10320 C  CA  . GLU E 1 155 ? -1.742  -1.157  37.172  1.00 31.75  ? 155 GLU E CA  1 
ATOM   10321 C  C   . GLU E 1 155 ? -0.981  -1.279  38.488  1.00 25.98  ? 155 GLU E C   1 
ATOM   10322 O  O   . GLU E 1 155 ? -1.487  -0.849  39.484  1.00 23.18  ? 155 GLU E O   1 
ATOM   10323 C  CB  . GLU E 1 155 ? -3.207  -1.592  37.330  1.00 34.35  ? 155 GLU E CB  1 
ATOM   10324 C  CG  . GLU E 1 155 ? -4.090  -1.077  36.190  1.00 38.99  ? 155 GLU E CG  1 
ATOM   10325 C  CD  . GLU E 1 155 ? -4.235  0.433   36.063  1.00 40.52  ? 155 GLU E CD  1 
ATOM   10326 O  OE1 . GLU E 1 155 ? -4.326  1.056   37.149  1.00 40.25  ? 155 GLU E OE1 1 
ATOM   10327 O  OE2 . GLU E 1 155 ? -4.348  0.979   34.918  1.00 46.62  ? 155 GLU E OE2 1 
ATOM   10328 N  N   . ASN E 1 156 ? 0.244   -1.807  38.538  1.00 27.61  ? 156 ASN E N   1 
ATOM   10329 C  CA  . ASN E 1 156 ? 0.983   -1.781  39.794  1.00 26.83  ? 156 ASN E CA  1 
ATOM   10330 C  C   . ASN E 1 156 ? 1.191   -0.353  40.259  1.00 28.15  ? 156 ASN E C   1 
ATOM   10331 O  O   . ASN E 1 156 ? 1.440   0.524   39.445  1.00 33.92  ? 156 ASN E O   1 
ATOM   10332 C  CB  . ASN E 1 156 ? 2.395   -2.337  39.688  1.00 26.77  ? 156 ASN E CB  1 
ATOM   10333 C  CG  . ASN E 1 156 ? 2.455   -3.821  39.942  1.00 29.23  ? 156 ASN E CG  1 
ATOM   10334 O  OD1 . ASN E 1 156 ? 1.743   -4.353  40.806  1.00 34.39  ? 156 ASN E OD1 1 
ATOM   10335 N  ND2 . ASN E 1 156 ? 3.277   -4.520  39.184  1.00 26.77  ? 156 ASN E ND2 1 
ATOM   10336 N  N   . PRO E 1 157 ? 1.138   -0.060  41.570  1.00 34.04  ? 157 PRO E N   1 
ATOM   10337 C  CA  . PRO E 1 157 ? 1.405   1.304   42.039  1.00 34.76  ? 157 PRO E CA  1 
ATOM   10338 C  C   . PRO E 1 157 ? 2.885   1.625   41.829  1.00 33.39  ? 157 PRO E C   1 
ATOM   10339 O  O   . PRO E 1 157 ? 3.693   0.711   41.650  1.00 33.00  ? 157 PRO E O   1 
ATOM   10340 C  CB  . PRO E 1 157 ? 1.018   1.209   43.524  1.00 38.87  ? 157 PRO E CB  1 
ATOM   10341 C  CG  . PRO E 1 157 ? 1.289   -0.262  43.885  1.00 36.78  ? 157 PRO E CG  1 
ATOM   10342 C  CD  . PRO E 1 157 ? 0.823   -1.014  42.653  1.00 36.87  ? 157 PRO E CD  1 
ATOM   10343 N  N   . THR E 1 158 ? 3.214   2.924   41.783  1.00 35.31  ? 158 THR E N   1 
ATOM   10344 C  CA  . THR E 1 158 ? 4.592   3.384   41.660  1.00 40.96  ? 158 THR E CA  1 
ATOM   10345 C  C   . THR E 1 158 ? 4.875   4.540   42.626  1.00 46.59  ? 158 THR E C   1 
ATOM   10346 O  O   . THR E 1 158 ? 3.968   5.177   43.177  1.00 42.93  ? 158 THR E O   1 
ATOM   10347 C  CB  . THR E 1 158 ? 4.920   3.800   40.231  1.00 40.97  ? 158 THR E CB  1 
ATOM   10348 O  OG1 . THR E 1 158 ? 3.895   4.756   39.992  1.00 35.19  ? 158 THR E OG1 1 
ATOM   10349 C  CG2 . THR E 1 158 ? 4.900   2.629   39.257  1.00 46.76  ? 158 THR E CG2 1 
ATOM   10350 N  N   . GLY E 1 159 ? 6.179   4.766   42.838  1.00 48.06  ? 159 GLY E N   1 
ATOM   10351 C  CA  . GLY E 1 159 ? 6.672   5.839   43.683  1.00 47.52  ? 159 GLY E CA  1 
ATOM   10352 C  C   . GLY E 1 159 ? 6.061   5.798   45.076  1.00 49.92  ? 159 GLY E C   1 
ATOM   10353 O  O   . GLY E 1 159 ? 6.113   4.761   45.728  1.00 51.22  ? 159 GLY E O   1 
ATOM   10354 N  N   . ALA E 1 160 ? 5.497   6.939   45.509  1.00 50.86  ? 160 ALA E N   1 
ATOM   10355 C  CA  . ALA E 1 160 ? 5.079   7.114   46.889  1.00 50.66  ? 160 ALA E CA  1 
ATOM   10356 C  C   . ALA E 1 160 ? 3.871   6.217   47.170  1.00 52.44  ? 160 ALA E C   1 
ATOM   10357 O  O   . ALA E 1 160 ? 3.728   5.695   48.269  1.00 50.62  ? 160 ALA E O   1 
ATOM   10358 C  CB  . ALA E 1 160 ? 4.785   8.577   47.152  1.00 47.41  ? 160 ALA E CB  1 
ATOM   10359 N  N   . ALA E 1 161 ? 3.008   6.032   46.157  1.00 48.73  ? 161 ALA E N   1 
ATOM   10360 C  CA  . ALA E 1 161 ? 1.836   5.188   46.321  1.00 46.35  ? 161 ALA E CA  1 
ATOM   10361 C  C   . ALA E 1 161 ? 2.263   3.740   46.632  1.00 47.63  ? 161 ALA E C   1 
ATOM   10362 O  O   . ALA E 1 161 ? 1.629   3.039   47.435  1.00 49.26  ? 161 ALA E O   1 
ATOM   10363 C  CB  . ALA E 1 161 ? 0.950   5.283   45.100  1.00 41.65  ? 161 ALA E CB  1 
ATOM   10364 N  N   . ALA E 1 162 ? 3.359   3.299   46.004  1.00 37.59  ? 162 ALA E N   1 
ATOM   10365 C  CA  . ALA E 1 162 ? 3.854   1.955   46.202  1.00 37.92  ? 162 ALA E CA  1 
ATOM   10366 C  C   . ALA E 1 162 ? 4.454   1.814   47.605  1.00 41.69  ? 162 ALA E C   1 
ATOM   10367 O  O   . ALA E 1 162 ? 4.144   0.846   48.309  1.00 43.22  ? 162 ALA E O   1 
ATOM   10368 C  CB  . ALA E 1 162 ? 4.829   1.604   45.100  1.00 36.58  ? 162 ALA E CB  1 
ATOM   10369 N  N   . ARG E 1 163 ? 5.298   2.782   48.014  1.00 47.79  ? 163 ARG E N   1 
ATOM   10370 C  CA  . ARG E 1 163 ? 5.830   2.829   49.370  1.00 46.73  ? 163 ARG E CA  1 
ATOM   10371 C  C   . ARG E 1 163 ? 4.657   2.688   50.350  1.00 39.30  ? 163 ARG E C   1 
ATOM   10372 O  O   . ARG E 1 163 ? 4.717   1.810   51.197  1.00 39.37  ? 163 ARG E O   1 
ATOM   10373 C  CB  . ARG E 1 163 ? 6.731   4.053   49.631  1.00 52.21  ? 163 ARG E CB  1 
ATOM   10374 C  CG  . ARG E 1 163 ? 8.112   4.157   48.992  1.00 52.32  ? 163 ARG E CG  1 
ATOM   10375 C  CD  . ARG E 1 163 ? 8.809   5.503   49.381  1.00 47.77  ? 163 ARG E CD  1 
ATOM   10376 N  N   . ARG E 1 164 ? 3.563   3.450   50.171  1.00 36.58  ? 164 ARG E N   1 
ATOM   10377 C  CA  . ARG E 1 164 ? 2.399   3.434   51.067  1.00 39.65  ? 164 ARG E CA  1 
ATOM   10378 C  C   . ARG E 1 164 ? 1.731   2.045   51.029  1.00 39.45  ? 164 ARG E C   1 
ATOM   10379 O  O   . ARG E 1 164 ? 1.210   1.571   52.050  1.00 43.39  ? 164 ARG E O   1 
ATOM   10380 C  CB  . ARG E 1 164 ? 1.437   4.659   50.890  1.00 40.23  ? 164 ARG E CB  1 
ATOM   10381 C  CG  . ARG E 1 164 ? -0.064  4.765   51.243  1.00 32.39  ? 164 ARG E CG  1 
ATOM   10382 N  N   . ALA E 1 165 ? 1.720   1.358   49.884  1.00 29.38  ? 165 ALA E N   1 
ATOM   10383 C  CA  . ALA E 1 165 ? 0.961   0.123   49.807  1.00 26.70  ? 165 ALA E CA  1 
ATOM   10384 C  C   . ALA E 1 165 ? 1.746   -1.082  50.326  1.00 30.16  ? 165 ALA E C   1 
ATOM   10385 O  O   . ALA E 1 165 ? 1.171   -2.118  50.652  1.00 26.83  ? 165 ALA E O   1 
ATOM   10386 C  CB  . ALA E 1 165 ? 0.557   -0.122  48.388  1.00 32.12  ? 165 ALA E CB  1 
ATOM   10387 N  N   . VAL E 1 166 ? 3.079   -1.005  50.335  1.00 31.79  ? 166 VAL E N   1 
ATOM   10388 C  CA  . VAL E 1 166 ? 3.883   -2.218  50.417  1.00 35.93  ? 166 VAL E CA  1 
ATOM   10389 C  C   . VAL E 1 166 ? 4.646   -2.315  51.738  1.00 36.92  ? 166 VAL E C   1 
ATOM   10390 O  O   . VAL E 1 166 ? 4.923   -3.422  52.219  1.00 32.85  ? 166 VAL E O   1 
ATOM   10391 C  CB  . VAL E 1 166 ? 4.867   -2.156  49.222  1.00 41.28  ? 166 VAL E CB  1 
ATOM   10392 C  CG1 . VAL E 1 166 ? 6.119   -2.994  49.455  1.00 43.54  ? 166 VAL E CG1 1 
ATOM   10393 C  CG2 . VAL E 1 166 ? 4.225   -2.547  47.892  1.00 41.26  ? 166 VAL E CG2 1 
ATOM   10394 N  N   . LEU E 1 167 ? 5.038   -1.160  52.302  1.00 39.58  ? 167 LEU E N   1 
ATOM   10395 C  CA  . LEU E 1 167 ? 5.970   -1.153  53.424  1.00 40.95  ? 167 LEU E CA  1 
ATOM   10396 C  C   . LEU E 1 167 ? 5.239   -0.974  54.750  1.00 40.68  ? 167 LEU E C   1 
ATOM   10397 O  O   . LEU E 1 167 ? 4.395   -0.082  54.903  1.00 37.86  ? 167 LEU E O   1 
ATOM   10398 C  CB  . LEU E 1 167 ? 7.007   -0.059  53.220  1.00 39.37  ? 167 LEU E CB  1 
ATOM   10399 C  CG  . LEU E 1 167 ? 7.905   -0.268  52.005  1.00 42.71  ? 167 LEU E CG  1 
ATOM   10400 C  CD1 . LEU E 1 167 ? 8.891   0.873   51.819  1.00 43.56  ? 167 LEU E CD1 1 
ATOM   10401 C  CD2 . LEU E 1 167 ? 8.645   -1.585  52.144  1.00 45.86  ? 167 LEU E CD2 1 
ATOM   10402 N  N   . VAL E 1 168 ? 5.600   -1.846  55.706  1.00 35.95  ? 168 VAL E N   1 
ATOM   10403 C  CA  . VAL E 1 168 ? 5.065   -1.759  57.039  1.00 37.55  ? 168 VAL E CA  1 
ATOM   10404 C  C   . VAL E 1 168 ? 5.478   -0.399  57.607  1.00 37.33  ? 168 VAL E C   1 
ATOM   10405 O  O   . VAL E 1 168 ? 6.604   0.049   57.409  1.00 34.13  ? 168 VAL E O   1 
ATOM   10406 C  CB  . VAL E 1 168 ? 5.600   -2.945  57.871  1.00 40.39  ? 168 VAL E CB  1 
ATOM   10407 C  CG1 . VAL E 1 168 ? 5.317   -2.785  59.366  1.00 42.81  ? 168 VAL E CG1 1 
ATOM   10408 C  CG2 . VAL E 1 168 ? 5.060   -4.286  57.372  1.00 36.92  ? 168 VAL E CG2 1 
ATOM   10409 N  N   . GLY E 1 169 ? 4.558   0.264   58.307  1.00 41.32  ? 169 GLY E N   1 
ATOM   10410 C  CA  . GLY E 1 169 ? 4.882   1.537   58.922  1.00 41.75  ? 169 GLY E CA  1 
ATOM   10411 C  C   . GLY E 1 169 ? 4.610   1.525   60.425  1.00 47.61  ? 169 GLY E C   1 
ATOM   10412 O  O   . GLY E 1 169 ? 4.951   0.579   61.153  1.00 44.67  ? 169 GLY E O   1 
ATOM   10413 N  N   . ALA E 1 170 ? 3.982   2.626   60.852  1.00 52.78  ? 170 ALA E N   1 
ATOM   10414 C  CA  . ALA E 1 170 ? 3.671   2.925   62.238  1.00 49.84  ? 170 ALA E CA  1 
ATOM   10415 C  C   . ALA E 1 170 ? 2.780   1.878   62.898  1.00 50.53  ? 170 ALA E C   1 
ATOM   10416 O  O   . ALA E 1 170 ? 2.824   1.738   64.108  1.00 68.30  ? 170 ALA E O   1 
ATOM   10417 C  CB  . ALA E 1 170 ? 2.981   4.264   62.250  1.00 51.34  ? 170 ALA E CB  1 
ATOM   10418 N  N   . GLU E 1 171 ? 1.962   1.158   62.123  1.00 45.54  ? 171 GLU E N   1 
ATOM   10419 C  CA  . GLU E 1 171 ? 1.023   0.202   62.692  1.00 40.34  ? 171 GLU E CA  1 
ATOM   10420 C  C   . GLU E 1 171 ? 1.738   -1.009  63.305  1.00 38.07  ? 171 GLU E C   1 
ATOM   10421 O  O   . GLU E 1 171 ? 1.100   -1.804  63.986  1.00 35.18  ? 171 GLU E O   1 
ATOM   10422 C  CB  . GLU E 1 171 ? -0.028  -0.202  61.647  1.00 44.18  ? 171 GLU E CB  1 
ATOM   10423 C  CG  . GLU E 1 171 ? 0.419   -1.227  60.595  1.00 44.29  ? 171 GLU E CG  1 
ATOM   10424 C  CD  . GLU E 1 171 ? 1.364   -0.774  59.482  1.00 43.95  ? 171 GLU E CD  1 
ATOM   10425 O  OE1 . GLU E 1 171 ? 1.761   0.415   59.459  1.00 37.21  ? 171 GLU E OE1 1 
ATOM   10426 O  OE2 . GLU E 1 171 ? 1.706   -1.628  58.625  1.00 37.31  ? 171 GLU E OE2 1 
ATOM   10427 N  N   . ASP E 1 172 ? 3.045   -1.186  63.050  1.00 38.92  ? 172 ASP E N   1 
ATOM   10428 C  CA  . ASP E 1 172 ? 3.823   -2.271  63.638  1.00 35.42  ? 172 ASP E CA  1 
ATOM   10429 C  C   . ASP E 1 172 ? 5.283   -1.829  63.649  1.00 34.64  ? 172 ASP E C   1 
ATOM   10430 O  O   . ASP E 1 172 ? 6.127   -2.350  62.913  1.00 35.37  ? 172 ASP E O   1 
ATOM   10431 C  CB  . ASP E 1 172 ? 3.618   -3.584  62.886  1.00 34.38  ? 172 ASP E CB  1 
ATOM   10432 C  CG  . ASP E 1 172 ? 4.154   -4.824  63.580  1.00 34.87  ? 172 ASP E CG  1 
ATOM   10433 O  OD1 . ASP E 1 172 ? 4.532   -4.691  64.741  1.00 36.72  ? 172 ASP E OD1 1 
ATOM   10434 O  OD2 . ASP E 1 172 ? 4.186   -5.905  62.946  1.00 38.79  ? 172 ASP E OD2 1 
ATOM   10435 N  N   . PRO E 1 173 ? 5.602   -0.818  64.476  1.00 36.84  ? 173 PRO E N   1 
ATOM   10436 C  CA  . PRO E 1 173 ? 6.810   -0.001  64.295  1.00 37.74  ? 173 PRO E CA  1 
ATOM   10437 C  C   . PRO E 1 173 ? 8.140   -0.731  64.468  1.00 33.83  ? 173 PRO E C   1 
ATOM   10438 O  O   . PRO E 1 173 ? 9.164   -0.320  63.919  1.00 33.81  ? 173 PRO E O   1 
ATOM   10439 C  CB  . PRO E 1 173 ? 6.660   1.136   65.314  1.00 38.50  ? 173 PRO E CB  1 
ATOM   10440 C  CG  . PRO E 1 173 ? 5.652   0.611   66.327  1.00 37.90  ? 173 PRO E CG  1 
ATOM   10441 C  CD  . PRO E 1 173 ? 4.787   -0.418  65.626  1.00 37.04  ? 173 PRO E CD  1 
ATOM   10442 N  N   . ALA E 1 174 ? 8.121   -1.821  65.235  1.00 33.15  ? 174 ALA E N   1 
ATOM   10443 C  CA  . ALA E 1 174 ? 9.300   -2.662  65.365  1.00 29.93  ? 174 ALA E CA  1 
ATOM   10444 C  C   . ALA E 1 174 ? 9.741   -3.240  64.019  1.00 32.79  ? 174 ALA E C   1 
ATOM   10445 O  O   . ALA E 1 174 ? 10.893  -3.621  63.918  1.00 36.54  ? 174 ALA E O   1 
ATOM   10446 C  CB  . ALA E 1 174 ? 9.001   -3.790  66.308  1.00 34.37  ? 174 ALA E CB  1 
ATOM   10447 N  N   . PHE E 1 175 ? 8.836   -3.365  63.030  1.00 33.62  ? 175 PHE E N   1 
ATOM   10448 C  CA  . PHE E 1 175 ? 9.098   -4.074  61.773  1.00 34.52  ? 175 PHE E CA  1 
ATOM   10449 C  C   . PHE E 1 175 ? 8.894   -3.190  60.543  1.00 31.11  ? 175 PHE E C   1 
ATOM   10450 O  O   . PHE E 1 175 ? 8.870   -3.690  59.427  1.00 31.22  ? 175 PHE E O   1 
ATOM   10451 C  CB  . PHE E 1 175 ? 8.186   -5.304  61.727  1.00 33.26  ? 175 PHE E CB  1 
ATOM   10452 C  CG  . PHE E 1 175 ? 8.542   -6.307  62.802  1.00 31.69  ? 175 PHE E CG  1 
ATOM   10453 C  CD1 . PHE E 1 175 ? 9.717   -7.020  62.695  1.00 33.26  ? 175 PHE E CD1 1 
ATOM   10454 C  CD2 . PHE E 1 175 ? 7.732   -6.518  63.918  1.00 37.33  ? 175 PHE E CD2 1 
ATOM   10455 C  CE1 . PHE E 1 175 ? 10.081  -7.939  63.664  1.00 34.00  ? 175 PHE E CE1 1 
ATOM   10456 C  CE2 . PHE E 1 175 ? 8.099   -7.443  64.885  1.00 35.77  ? 175 PHE E CE2 1 
ATOM   10457 C  CZ  . PHE E 1 175 ? 9.268   -8.152  64.745  1.00 34.50  ? 175 PHE E CZ  1 
ATOM   10458 N  N   . ALA E 1 176 ? 8.777   -1.881  60.768  1.00 32.39  ? 176 ALA E N   1 
ATOM   10459 C  CA  . ALA E 1 176 ? 8.738   -0.883  59.706  1.00 35.29  ? 176 ALA E CA  1 
ATOM   10460 C  C   . ALA E 1 176 ? 9.856   -1.128  58.693  1.00 39.51  ? 176 ALA E C   1 
ATOM   10461 O  O   . ALA E 1 176 ? 11.008  -1.333  59.092  1.00 42.79  ? 176 ALA E O   1 
ATOM   10462 C  CB  . ALA E 1 176 ? 8.864   0.503   60.311  1.00 28.38  ? 176 ALA E CB  1 
ATOM   10463 N  N   . GLY E 1 177 ? 9.485   -1.108  57.396  1.00 39.86  ? 177 GLY E N   1 
ATOM   10464 C  CA  . GLY E 1 177 ? 10.406  -1.315  56.278  1.00 41.56  ? 177 GLY E CA  1 
ATOM   10465 C  C   . GLY E 1 177 ? 10.284  -2.727  55.693  1.00 41.04  ? 177 GLY E C   1 
ATOM   10466 O  O   . GLY E 1 177 ? 10.910  -3.113  54.681  1.00 42.54  ? 177 GLY E O   1 
ATOM   10467 N  N   . GLY E 1 178 ? 9.481   -3.515  56.404  1.00 38.33  ? 178 GLY E N   1 
ATOM   10468 C  CA  . GLY E 1 178 ? 9.206   -4.870  55.990  1.00 34.96  ? 178 GLY E CA  1 
ATOM   10469 C  C   . GLY E 1 178 ? 8.003   -4.884  55.071  1.00 30.60  ? 178 GLY E C   1 
ATOM   10470 O  O   . GLY E 1 178 ? 7.396   -3.835  54.789  1.00 29.79  ? 178 GLY E O   1 
ATOM   10471 N  N   . SER E 1 179 ? 7.710   -6.096  54.615  1.00 26.57  ? 179 SER E N   1 
ATOM   10472 C  CA  . SER E 1 179 ? 6.587   -6.321  53.742  1.00 26.94  ? 179 SER E CA  1 
ATOM   10473 C  C   . SER E 1 179 ? 6.200   -7.795  53.854  1.00 27.89  ? 179 SER E C   1 
ATOM   10474 O  O   . SER E 1 179 ? 6.907   -8.601  54.476  1.00 26.79  ? 179 SER E O   1 
ATOM   10475 C  CB  . SER E 1 179 ? 6.908   -5.906  52.336  1.00 27.32  ? 179 SER E CB  1 
ATOM   10476 O  OG  . SER E 1 179 ? 5.743   -5.813  51.528  1.00 29.09  ? 179 SER E OG  1 
ATOM   10477 N  N   . TYR E 1 180 ? 5.044   -8.109  53.262  1.00 27.27  ? 180 TYR E N   1 
ATOM   10478 C  CA  . TYR E 1 180 ? 4.515   -9.452  53.282  1.00 31.01  ? 180 TYR E CA  1 
ATOM   10479 C  C   . TYR E 1 180 ? 4.412   -9.912  51.840  1.00 29.81  ? 180 TYR E C   1 
ATOM   10480 O  O   . TYR E 1 180 ? 3.746   -9.269  51.021  1.00 29.28  ? 180 TYR E O   1 
ATOM   10481 C  CB  . TYR E 1 180 ? 3.156   -9.529  54.003  1.00 32.51  ? 180 TYR E CB  1 
ATOM   10482 C  CG  . TYR E 1 180 ? 3.213   -9.240  55.494  1.00 30.64  ? 180 TYR E CG  1 
ATOM   10483 C  CD1 . TYR E 1 180 ? 3.114   -7.928  55.969  1.00 29.55  ? 180 TYR E CD1 1 
ATOM   10484 C  CD2 . TYR E 1 180 ? 3.379   -10.266 56.414  1.00 29.25  ? 180 TYR E CD2 1 
ATOM   10485 C  CE1 . TYR E 1 180 ? 3.182   -7.655  57.325  1.00 28.11  ? 180 TYR E CE1 1 
ATOM   10486 C  CE2 . TYR E 1 180 ? 3.439   -10.000 57.778  1.00 26.78  ? 180 TYR E CE2 1 
ATOM   10487 C  CZ  . TYR E 1 180 ? 3.327   -8.697  58.224  1.00 23.89  ? 180 TYR E CZ  1 
ATOM   10488 O  OH  . TYR E 1 180 ? 3.392   -8.419  59.546  1.00 24.80  ? 180 TYR E OH  1 
ATOM   10489 N  N   . ALA E 1 181 ? 4.994   -11.088 51.602  1.00 28.47  ? 181 ALA E N   1 
ATOM   10490 C  CA  . ALA E 1 181 ? 5.006   -11.670 50.281  1.00 30.33  ? 181 ALA E CA  1 
ATOM   10491 C  C   . ALA E 1 181 ? 4.175   -12.947 50.279  1.00 27.39  ? 181 ALA E C   1 
ATOM   10492 O  O   . ALA E 1 181 ? 4.396   -13.830 51.109  1.00 24.75  ? 181 ALA E O   1 
ATOM   10493 C  CB  . ALA E 1 181 ? 6.448   -11.924 49.852  1.00 34.06  ? 181 ALA E CB  1 
ATOM   10494 N  N   . VAL E 1 182 ? 3.270   -13.028 49.293  1.00 25.84  ? 182 VAL E N   1 
ATOM   10495 C  CA  . VAL E 1 182 ? 2.582   -14.268 48.989  1.00 25.61  ? 182 VAL E CA  1 
ATOM   10496 C  C   . VAL E 1 182 ? 3.084   -14.768 47.645  1.00 24.16  ? 182 VAL E C   1 
ATOM   10497 O  O   . VAL E 1 182 ? 3.115   -13.995 46.702  1.00 20.10  ? 182 VAL E O   1 
ATOM   10498 C  CB  . VAL E 1 182 ? 1.061   -14.046 48.964  1.00 24.98  ? 182 VAL E CB  1 
ATOM   10499 C  CG1 . VAL E 1 182 ? 0.322   -15.287 48.533  1.00 26.68  ? 182 VAL E CG1 1 
ATOM   10500 C  CG2 . VAL E 1 182 ? 0.539   -13.551 50.304  1.00 26.93  ? 182 VAL E CG2 1 
ATOM   10501 N  N   . VAL E 1 183 ? 3.406   -16.065 47.576  1.00 25.39  ? 183 VAL E N   1 
ATOM   10502 C  CA  . VAL E 1 183 ? 3.796   -16.704 46.330  1.00 28.58  ? 183 VAL E CA  1 
ATOM   10503 C  C   . VAL E 1 183 ? 2.805   -17.820 46.009  1.00 28.77  ? 183 VAL E C   1 
ATOM   10504 O  O   . VAL E 1 183 ? 2.332   -18.511 46.906  1.00 29.09  ? 183 VAL E O   1 
ATOM   10505 C  CB  . VAL E 1 183 ? 5.245   -17.247 46.338  1.00 28.21  ? 183 VAL E CB  1 
ATOM   10506 C  CG1 . VAL E 1 183 ? 6.264   -16.139 46.572  1.00 29.32  ? 183 VAL E CG1 1 
ATOM   10507 C  CG2 . VAL E 1 183 ? 5.456   -18.375 47.340  1.00 26.49  ? 183 VAL E CG2 1 
ATOM   10508 N  N   . GLN E 1 184 ? 2.521   -17.978 44.715  1.00 28.48  ? 184 GLN E N   1 
ATOM   10509 C  CA  . GLN E 1 184 ? 1.828   -19.149 44.198  1.00 28.23  ? 184 GLN E CA  1 
ATOM   10510 C  C   . GLN E 1 184 ? 2.372   -19.464 42.809  1.00 25.43  ? 184 GLN E C   1 
ATOM   10511 O  O   . GLN E 1 184 ? 2.476   -18.591 41.934  1.00 22.09  ? 184 GLN E O   1 
ATOM   10512 C  CB  . GLN E 1 184 ? 0.326   -18.942 44.000  1.00 30.25  ? 184 GLN E CB  1 
ATOM   10513 C  CG  . GLN E 1 184 ? -0.464  -18.623 45.264  1.00 35.88  ? 184 GLN E CG  1 
ATOM   10514 C  CD  . GLN E 1 184 ? -1.936  -18.409 44.948  1.00 35.44  ? 184 GLN E CD  1 
ATOM   10515 O  OE1 . GLN E 1 184 ? -2.336  -17.388 44.375  1.00 25.80  ? 184 GLN E OE1 1 
ATOM   10516 N  NE2 . GLN E 1 184 ? -2.744  -19.422 45.232  1.00 37.75  ? 184 GLN E NE2 1 
ATOM   10517 N  N   . LYS E 1 185 ? 2.682   -20.736 42.589  1.00 24.07  ? 185 LYS E N   1 
ATOM   10518 C  CA  . LYS E 1 185 ? 3.081   -21.173 41.269  1.00 22.17  ? 185 LYS E CA  1 
ATOM   10519 C  C   . LYS E 1 185 ? 1.843   -21.665 40.546  1.00 23.64  ? 185 LYS E C   1 
ATOM   10520 O  O   . LYS E 1 185 ? 1.175   -22.546 41.058  1.00 24.49  ? 185 LYS E O   1 
ATOM   10521 C  CB  . LYS E 1 185 ? 4.134   -22.264 41.391  1.00 21.50  ? 185 LYS E CB  1 
ATOM   10522 C  CG  . LYS E 1 185 ? 4.481   -22.863 40.081  1.00 24.78  ? 185 LYS E CG  1 
ATOM   10523 C  CD  . LYS E 1 185 ? 5.851   -23.503 40.003  1.00 26.55  ? 185 LYS E CD  1 
ATOM   10524 C  CE  . LYS E 1 185 ? 5.844   -24.784 40.733  1.00 29.30  ? 185 LYS E CE  1 
ATOM   10525 N  NZ  . LYS E 1 185 ? 7.186   -25.373 40.639  1.00 31.24  ? 185 LYS E NZ  1 
ATOM   10526 N  N   . TYR E 1 186 ? 1.530   -21.072 39.384  1.00 26.42  ? 186 TYR E N   1 
ATOM   10527 C  CA  . TYR E 1 186 ? 0.378   -21.462 38.562  1.00 25.43  ? 186 TYR E CA  1 
ATOM   10528 C  C   . TYR E 1 186 ? 0.842   -22.177 37.295  1.00 28.54  ? 186 TYR E C   1 
ATOM   10529 O  O   . TYR E 1 186 ? 1.821   -21.778 36.678  1.00 30.37  ? 186 TYR E O   1 
ATOM   10530 C  CB  . TYR E 1 186 ? -0.468  -20.270 38.136  1.00 24.57  ? 186 TYR E CB  1 
ATOM   10531 C  CG  . TYR E 1 186 ? -1.329  -19.663 39.228  1.00 28.40  ? 186 TYR E CG  1 
ATOM   10532 C  CD1 . TYR E 1 186 ? -2.619  -20.148 39.465  1.00 31.47  ? 186 TYR E CD1 1 
ATOM   10533 C  CD2 . TYR E 1 186 ? -0.862  -18.629 40.035  1.00 28.53  ? 186 TYR E CD2 1 
ATOM   10534 C  CE1 . TYR E 1 186 ? -3.402  -19.605 40.475  1.00 34.17  ? 186 TYR E CE1 1 
ATOM   10535 C  CE2 . TYR E 1 186 ? -1.629  -18.104 41.064  1.00 33.32  ? 186 TYR E CE2 1 
ATOM   10536 C  CZ  . TYR E 1 186 ? -2.917  -18.567 41.265  1.00 35.37  ? 186 TYR E CZ  1 
ATOM   10537 O  OH  . TYR E 1 186 ? -3.654  -17.965 42.233  1.00 33.52  ? 186 TYR E OH  1 
ATOM   10538 N  N   . LEU E 1 187 ? 0.119   -23.230 36.911  1.00 26.76  ? 187 LEU E N   1 
ATOM   10539 C  CA  . LEU E 1 187 ? 0.285   -23.852 35.614  1.00 25.19  ? 187 LEU E CA  1 
ATOM   10540 C  C   . LEU E 1 187 ? -0.946  -23.562 34.777  1.00 29.99  ? 187 LEU E C   1 
ATOM   10541 O  O   . LEU E 1 187 ? -2.045  -23.530 35.311  1.00 32.82  ? 187 LEU E O   1 
ATOM   10542 C  CB  . LEU E 1 187 ? 0.504   -25.340 35.766  1.00 24.49  ? 187 LEU E CB  1 
ATOM   10543 C  CG  . LEU E 1 187 ? 1.760   -25.727 36.539  1.00 29.02  ? 187 LEU E CG  1 
ATOM   10544 C  CD1 . LEU E 1 187 ? 1.755   -27.188 36.864  1.00 30.82  ? 187 LEU E CD1 1 
ATOM   10545 C  CD2 . LEU E 1 187 ? 2.985   -25.359 35.715  1.00 34.91  ? 187 LEU E CD2 1 
ATOM   10546 N  N   . HIS E 1 188 ? -0.755  -23.320 33.471  1.00 26.24  ? 188 HIS E N   1 
ATOM   10547 C  CA  . HIS E 1 188 ? -1.857  -22.924 32.634  1.00 25.47  ? 188 HIS E CA  1 
ATOM   10548 C  C   . HIS E 1 188 ? -2.180  -24.064 31.678  1.00 30.01  ? 188 HIS E C   1 
ATOM   10549 O  O   . HIS E 1 188 ? -1.308  -24.838 31.299  1.00 31.97  ? 188 HIS E O   1 
ATOM   10550 C  CB  . HIS E 1 188 ? -1.502  -21.706 31.805  1.00 24.11  ? 188 HIS E CB  1 
ATOM   10551 C  CG  . HIS E 1 188 ? -1.246  -20.488 32.591  1.00 24.59  ? 188 HIS E CG  1 
ATOM   10552 N  ND1 . HIS E 1 188 ? -2.260  -19.810 33.216  1.00 25.70  ? 188 HIS E ND1 1 
ATOM   10553 C  CD2 . HIS E 1 188 ? -0.136  -19.810 32.821  1.00 22.82  ? 188 HIS E CD2 1 
ATOM   10554 C  CE1 . HIS E 1 188 ? -1.767  -18.724 33.797  1.00 28.94  ? 188 HIS E CE1 1 
ATOM   10555 N  NE2 . HIS E 1 188 ? -0.461  -18.702 33.559  1.00 25.86  ? 188 HIS E NE2 1 
ATOM   10556 N  N   . ASP E 1 189 ? -3.455  -24.136 31.297  1.00 33.04  ? 189 ASP E N   1 
ATOM   10557 C  CA  . ASP E 1 189 ? -3.920  -24.990 30.228  1.00 30.14  ? 189 ASP E CA  1 
ATOM   10558 C  C   . ASP E 1 189 ? -3.936  -24.110 28.995  1.00 29.85  ? 189 ASP E C   1 
ATOM   10559 O  O   . ASP E 1 189 ? -4.931  -23.449 28.695  1.00 27.28  ? 189 ASP E O   1 
ATOM   10560 C  CB  . ASP E 1 189 ? -5.303  -25.555 30.522  1.00 30.76  ? 189 ASP E CB  1 
ATOM   10561 C  CG  . ASP E 1 189 ? -5.799  -26.522 29.467  1.00 30.98  ? 189 ASP E CG  1 
ATOM   10562 O  OD1 . ASP E 1 189 ? -5.201  -26.582 28.394  1.00 33.57  ? 189 ASP E OD1 1 
ATOM   10563 O  OD2 . ASP E 1 189 ? -6.747  -27.260 29.744  1.00 34.95  ? 189 ASP E OD2 1 
ATOM   10564 N  N   . ILE E 1 190 ? -2.806  -24.076 28.302  1.00 30.38  ? 190 ILE E N   1 
ATOM   10565 C  CA  . ILE E 1 190 ? -2.661  -23.144 27.201  1.00 32.59  ? 190 ILE E CA  1 
ATOM   10566 C  C   . ILE E 1 190 ? -3.554  -23.553 26.030  1.00 32.30  ? 190 ILE E C   1 
ATOM   10567 O  O   . ILE E 1 190 ? -4.021  -22.683 25.308  1.00 32.51  ? 190 ILE E O   1 
ATOM   10568 C  CB  . ILE E 1 190 ? -1.185  -23.059 26.772  1.00 37.87  ? 190 ILE E CB  1 
ATOM   10569 C  CG1 . ILE E 1 190 ? -0.317  -22.309 27.785  1.00 37.25  ? 190 ILE E CG1 1 
ATOM   10570 C  CG2 . ILE E 1 190 ? -1.101  -22.385 25.412  1.00 41.16  ? 190 ILE E CG2 1 
ATOM   10571 C  CD1 . ILE E 1 190 ? -0.706  -20.854 27.967  1.00 35.42  ? 190 ILE E CD1 1 
ATOM   10572 N  N   . ASP E 1 191 ? -3.769  -24.853 25.817  1.00 31.42  ? 191 ASP E N   1 
ATOM   10573 C  CA  . ASP E 1 191 ? -4.600  -25.319 24.711  1.00 30.20  ? 191 ASP E CA  1 
ATOM   10574 C  C   . ASP E 1 191 ? -6.004  -24.774 24.874  1.00 32.36  ? 191 ASP E C   1 
ATOM   10575 O  O   . ASP E 1 191 ? -6.576  -24.271 23.937  1.00 33.62  ? 191 ASP E O   1 
ATOM   10576 C  CB  . ASP E 1 191 ? -4.784  -26.824 24.662  1.00 34.75  ? 191 ASP E CB  1 
ATOM   10577 C  CG  . ASP E 1 191 ? -3.508  -27.618 24.490  1.00 42.81  ? 191 ASP E CG  1 
ATOM   10578 O  OD1 . ASP E 1 191 ? -2.603  -27.132 23.763  1.00 39.98  ? 191 ASP E OD1 1 
ATOM   10579 O  OD2 . ASP E 1 191 ? -3.441  -28.701 25.099  1.00 62.57  ? 191 ASP E OD2 1 
ATOM   10580 N  N   . ALA E 1 192 ? -6.555  -24.882 26.079  1.00 30.57  ? 192 ALA E N   1 
ATOM   10581 C  CA  . ALA E 1 192 ? -7.866  -24.335 26.361  1.00 29.99  ? 192 ALA E CA  1 
ATOM   10582 C  C   . ALA E 1 192 ? -7.903  -22.844 26.082  1.00 30.52  ? 192 ALA E C   1 
ATOM   10583 O  O   . ALA E 1 192 ? -8.838  -22.335 25.479  1.00 36.86  ? 192 ALA E O   1 
ATOM   10584 C  CB  . ALA E 1 192 ? -8.239  -24.618 27.799  1.00 28.24  ? 192 ALA E CB  1 
ATOM   10585 N  N   . TRP E 1 193 ? -6.894  -22.140 26.578  1.00 31.88  ? 193 TRP E N   1 
ATOM   10586 C  CA  . TRP E 1 193 ? -6.834  -20.688 26.505  1.00 30.51  ? 193 TRP E CA  1 
ATOM   10587 C  C   . TRP E 1 193 ? -6.835  -20.223 25.053  1.00 31.27  ? 193 TRP E C   1 
ATOM   10588 O  O   . TRP E 1 193 ? -7.587  -19.319 24.679  1.00 26.63  ? 193 TRP E O   1 
ATOM   10589 C  CB  . TRP E 1 193 ? -5.569  -20.206 27.229  1.00 29.49  ? 193 TRP E CB  1 
ATOM   10590 C  CG  . TRP E 1 193 ? -5.404  -18.719 27.223  1.00 25.94  ? 193 TRP E CG  1 
ATOM   10591 C  CD1 . TRP E 1 193 ? -4.430  -18.022 26.598  1.00 28.24  ? 193 TRP E CD1 1 
ATOM   10592 C  CD2 . TRP E 1 193 ? -6.234  -17.748 27.872  1.00 24.69  ? 193 TRP E CD2 1 
ATOM   10593 N  NE1 . TRP E 1 193 ? -4.573  -16.684 26.833  1.00 27.79  ? 193 TRP E NE1 1 
ATOM   10594 C  CE2 . TRP E 1 193 ? -5.682  -16.483 27.595  1.00 24.70  ? 193 TRP E CE2 1 
ATOM   10595 C  CE3 . TRP E 1 193 ? -7.376  -17.831 28.669  1.00 26.35  ? 193 TRP E CE3 1 
ATOM   10596 C  CZ2 . TRP E 1 193 ? -6.237  -15.298 28.061  1.00 24.40  ? 193 TRP E CZ2 1 
ATOM   10597 C  CZ3 . TRP E 1 193 ? -7.921  -16.658 29.144  1.00 27.86  ? 193 TRP E CZ3 1 
ATOM   10598 C  CH2 . TRP E 1 193 ? -7.375  -15.405 28.819  1.00 25.60  ? 193 TRP E CH2 1 
ATOM   10599 N  N   . GLU E 1 194 ? -6.013  -20.896 24.246  1.00 36.48  ? 194 GLU E N   1 
ATOM   10600 C  CA  . GLU E 1 194 ? -5.803  -20.548 22.858  1.00 41.49  ? 194 GLU E CA  1 
ATOM   10601 C  C   . GLU E 1 194 ? -7.036  -20.903 22.049  1.00 38.14  ? 194 GLU E C   1 
ATOM   10602 O  O   . GLU E 1 194 ? -7.149  -20.494 20.917  1.00 44.77  ? 194 GLU E O   1 
ATOM   10603 C  CB  . GLU E 1 194 ? -4.562  -21.252 22.284  1.00 46.69  ? 194 GLU E CB  1 
ATOM   10604 C  CG  . GLU E 1 194 ? -3.595  -20.297 21.589  1.00 58.92  ? 194 GLU E CG  1 
ATOM   10605 C  CD  . GLU E 1 194 ? -2.360  -20.033 22.437  1.00 66.76  ? 194 GLU E CD  1 
ATOM   10606 O  OE1 . GLU E 1 194 ? -1.448  -20.866 22.284  1.00 68.47  ? 194 GLU E OE1 1 
ATOM   10607 O  OE2 . GLU E 1 194 ? -2.339  -19.105 23.285  1.00 68.51  ? 194 GLU E OE2 1 
ATOM   10608 N  N   . GLY E 1 195 ? -7.979  -21.641 22.622  1.00 41.00  ? 195 GLY E N   1 
ATOM   10609 C  CA  . GLY E 1 195 ? -9.208  -21.931 21.909  1.00 39.01  ? 195 GLY E CA  1 
ATOM   10610 C  C   . GLY E 1 195 ? -10.230 -20.796 21.996  1.00 37.33  ? 195 GLY E C   1 
ATOM   10611 O  O   . GLY E 1 195 ? -11.234 -20.850 21.307  1.00 42.53  ? 195 GLY E O   1 
ATOM   10612 N  N   . LEU E 1 196 ? -10.022 -19.804 22.867  1.00 32.41  ? 196 LEU E N   1 
ATOM   10613 C  CA  . LEU E 1 196 ? -10.943 -18.687 22.936  1.00 32.51  ? 196 LEU E CA  1 
ATOM   10614 C  C   . LEU E 1 196 ? -10.593 -17.695 21.833  1.00 30.04  ? 196 LEU E C   1 
ATOM   10615 O  O   . LEU E 1 196 ? -9.431  -17.571 21.451  1.00 25.83  ? 196 LEU E O   1 
ATOM   10616 C  CB  . LEU E 1 196 ? -10.831 -18.030 24.308  1.00 36.20  ? 196 LEU E CB  1 
ATOM   10617 C  CG  . LEU E 1 196 ? -11.700 -18.633 25.408  1.00 37.30  ? 196 LEU E CG  1 
ATOM   10618 C  CD1 . LEU E 1 196 ? -11.562 -20.143 25.456  1.00 38.41  ? 196 LEU E CD1 1 
ATOM   10619 C  CD2 . LEU E 1 196 ? -11.376 -17.993 26.741  1.00 37.13  ? 196 LEU E CD2 1 
ATOM   10620 N  N   . SER E 1 197 ? -11.592 -16.956 21.373  1.00 26.15  ? 197 SER E N   1 
ATOM   10621 C  CA  . SER E 1 197 ? -11.303 -15.793 20.571  1.00 29.05  ? 197 SER E CA  1 
ATOM   10622 C  C   . SER E 1 197 ? -10.606 -14.743 21.444  1.00 32.09  ? 197 SER E C   1 
ATOM   10623 O  O   . SER E 1 197 ? -10.655 -14.788 22.662  1.00 30.51  ? 197 SER E O   1 
ATOM   10624 C  CB  . SER E 1 197 ? -12.557 -15.233 19.993  1.00 26.73  ? 197 SER E CB  1 
ATOM   10625 O  OG  . SER E 1 197 ? -13.340 -14.705 21.051  1.00 24.80  ? 197 SER E OG  1 
ATOM   10626 N  N   . VAL E 1 198 ? -9.991  -13.745 20.813  1.00 32.31  ? 198 VAL E N   1 
ATOM   10627 C  CA  . VAL E 1 198 ? -9.384  -12.678 21.566  1.00 29.46  ? 198 VAL E CA  1 
ATOM   10628 C  C   . VAL E 1 198 ? -10.448 -11.960 22.379  1.00 30.13  ? 198 VAL E C   1 
ATOM   10629 O  O   . VAL E 1 198 ? -10.143 -11.585 23.517  1.00 28.67  ? 198 VAL E O   1 
ATOM   10630 C  CB  . VAL E 1 198 ? -8.590  -11.727 20.654  1.00 30.14  ? 198 VAL E CB  1 
ATOM   10631 C  CG1 . VAL E 1 198 ? -8.281  -10.391 21.309  1.00 30.41  ? 198 VAL E CG1 1 
ATOM   10632 C  CG2 . VAL E 1 198 ? -7.288  -12.384 20.227  1.00 29.18  ? 198 VAL E CG2 1 
ATOM   10633 N  N   . GLU E 1 199 ? -11.662 -11.771 21.826  1.00 27.62  ? 199 GLU E N   1 
ATOM   10634 C  CA  . GLU E 1 199 ? -12.690 -10.984 22.511  1.00 30.82  ? 199 GLU E CA  1 
ATOM   10635 C  C   . GLU E 1 199 ? -13.077 -11.710 23.798  1.00 30.03  ? 199 GLU E C   1 
ATOM   10636 O  O   . GLU E 1 199 ? -13.223 -11.090 24.847  1.00 33.81  ? 199 GLU E O   1 
ATOM   10637 C  CB  . GLU E 1 199 ? -13.895 -10.647 21.614  1.00 35.76  ? 199 GLU E CB  1 
ATOM   10638 C  CG  . GLU E 1 199 ? -13.550 -9.735  20.423  1.00 39.68  ? 199 GLU E CG  1 
ATOM   10639 C  CD  . GLU E 1 199 ? -12.613 -10.244 19.274  1.00 43.44  ? 199 GLU E CD  1 
ATOM   10640 O  OE1 . GLU E 1 199 ? -12.470 -11.506 18.994  1.00 36.99  ? 199 GLU E OE1 1 
ATOM   10641 O  OE2 . GLU E 1 199 ? -11.998 -9.340  18.610  1.00 31.83  ? 199 GLU E OE2 1 
ATOM   10642 N  N   . ALA E 1 200 ? -13.133 -13.040 23.733  1.00 30.39  ? 200 ALA E N   1 
ATOM   10643 C  CA  . ALA E 1 200 ? -13.426 -13.875 24.894  1.00 33.80  ? 200 ALA E CA  1 
ATOM   10644 C  C   . ALA E 1 200 ? -12.336 -13.778 25.967  1.00 34.96  ? 200 ALA E C   1 
ATOM   10645 O  O   . ALA E 1 200 ? -12.632 -13.767 27.173  1.00 38.62  ? 200 ALA E O   1 
ATOM   10646 C  CB  . ALA E 1 200 ? -13.573 -15.326 24.461  1.00 33.32  ? 200 ALA E CB  1 
ATOM   10647 N  N   . GLN E 1 201 ? -11.067 -13.776 25.524  1.00 29.45  ? 201 GLN E N   1 
ATOM   10648 C  CA  . GLN E 1 201 ? -9.950  -13.700 26.450  1.00 27.68  ? 201 GLN E CA  1 
ATOM   10649 C  C   . GLN E 1 201 ? -9.982  -12.351 27.161  1.00 26.39  ? 201 GLN E C   1 
ATOM   10650 O  O   . GLN E 1 201 ? -9.677  -12.278 28.356  1.00 28.63  ? 201 GLN E O   1 
ATOM   10651 C  CB  . GLN E 1 201 ? -8.617  -13.837 25.728  1.00 25.27  ? 201 GLN E CB  1 
ATOM   10652 C  CG  . GLN E 1 201 ? -8.363  -15.198 25.113  1.00 23.99  ? 201 GLN E CG  1 
ATOM   10653 C  CD  . GLN E 1 201 ? -6.989  -15.269 24.469  1.00 24.74  ? 201 GLN E CD  1 
ATOM   10654 O  OE1 . GLN E 1 201 ? -6.274  -14.294 24.229  1.00 24.28  ? 201 GLN E OE1 1 
ATOM   10655 N  NE2 . GLN E 1 201 ? -6.564  -16.479 24.208  1.00 25.30  ? 201 GLN E NE2 1 
ATOM   10656 N  N   . GLU E 1 202 ? -10.363 -11.295 26.423  1.00 26.14  ? 202 GLU E N   1 
ATOM   10657 C  CA  . GLU E 1 202 ? -10.379 -9.956  26.992  1.00 28.26  ? 202 GLU E CA  1 
ATOM   10658 C  C   . GLU E 1 202 ? -11.430 -9.876  28.092  1.00 29.11  ? 202 GLU E C   1 
ATOM   10659 O  O   . GLU E 1 202 ? -11.276 -9.103  29.038  1.00 27.45  ? 202 GLU E O   1 
ATOM   10660 C  CB  . GLU E 1 202 ? -10.627 -8.909  25.910  1.00 29.73  ? 202 GLU E CB  1 
ATOM   10661 C  CG  . GLU E 1 202 ? -9.428  -8.702  24.986  1.00 31.97  ? 202 GLU E CG  1 
ATOM   10662 C  CD  . GLU E 1 202 ? -9.697  -7.896  23.733  1.00 32.92  ? 202 GLU E CD  1 
ATOM   10663 O  OE1 . GLU E 1 202 ? -10.865 -7.837  23.355  1.00 34.90  ? 202 GLU E OE1 1 
ATOM   10664 O  OE2 . GLU E 1 202 ? -8.758  -7.316  23.169  1.00 30.59  ? 202 GLU E OE2 1 
ATOM   10665 N  N   . ARG E 1 203 ? -12.493 -10.681 27.938  1.00 35.01  ? 203 ARG E N   1 
ATOM   10666 C  CA  . ARG E 1 203 ? -13.596 -10.704 28.884  1.00 41.26  ? 203 ARG E CA  1 
ATOM   10667 C  C   . ARG E 1 203 ? -13.162 -11.441 30.144  1.00 34.88  ? 203 ARG E C   1 
ATOM   10668 O  O   . ARG E 1 203 ? -13.637 -11.121 31.231  1.00 37.89  ? 203 ARG E O   1 
ATOM   10669 C  CB  . ARG E 1 203 ? -14.839 -11.372 28.284  1.00 49.22  ? 203 ARG E CB  1 
ATOM   10670 C  CG  . ARG E 1 203 ? -15.704 -10.441 27.454  1.00 54.01  ? 203 ARG E CG  1 
ATOM   10671 C  CD  . ARG E 1 203 ? -16.789 -11.215 26.653  1.00 61.50  ? 203 ARG E CD  1 
ATOM   10672 N  NE  . ARG E 1 203 ? -17.715 -10.312 25.949  1.00 71.53  ? 203 ARG E NE  1 
ATOM   10673 C  CZ  . ARG E 1 203 ? -17.383 -9.374  25.028  1.00 82.51  ? 203 ARG E CZ  1 
ATOM   10674 N  NH1 . ARG E 1 203 ? -18.269 -8.504  24.565  1.00 85.84  ? 203 ARG E NH1 1 
ATOM   10675 N  NH2 . ARG E 1 203 ? -16.152 -9.261  24.574  1.00 83.44  ? 203 ARG E NH2 1 
ATOM   10676 N  N   . VAL E 1 204 ? -12.246 -12.398 29.994  1.00 27.65  ? 204 VAL E N   1 
ATOM   10677 C  CA  . VAL E 1 204 ? -11.694 -13.079 31.150  1.00 27.87  ? 204 VAL E CA  1 
ATOM   10678 C  C   . VAL E 1 204 ? -10.767 -12.164 31.969  1.00 29.11  ? 204 VAL E C   1 
ATOM   10679 O  O   . VAL E 1 204 ? -10.773 -12.184 33.200  1.00 29.51  ? 204 VAL E O   1 
ATOM   10680 C  CB  . VAL E 1 204 ? -10.966 -14.358 30.725  1.00 28.31  ? 204 VAL E CB  1 
ATOM   10681 C  CG1 . VAL E 1 204 ? -10.211 -14.977 31.895  1.00 31.82  ? 204 VAL E CG1 1 
ATOM   10682 C  CG2 . VAL E 1 204 ? -11.924 -15.379 30.142  1.00 29.60  ? 204 VAL E CG2 1 
ATOM   10683 N  N   . ILE E 1 205 ? -9.949  -11.362 31.305  1.00 29.97  ? 205 ILE E N   1 
ATOM   10684 C  CA  . ILE E 1 205 ? -8.959  -10.559 31.997  1.00 31.75  ? 205 ILE E CA  1 
ATOM   10685 C  C   . ILE E 1 205 ? -9.617  -9.262  32.474  1.00 27.71  ? 205 ILE E C   1 
ATOM   10686 O  O   . ILE E 1 205 ? -9.456  -8.855  33.622  1.00 25.19  ? 205 ILE E O   1 
ATOM   10687 C  CB  . ILE E 1 205 ? -7.730  -10.317 31.076  1.00 30.65  ? 205 ILE E CB  1 
ATOM   10688 C  CG1 . ILE E 1 205 ? -7.074  -11.629 30.660  1.00 28.72  ? 205 ILE E CG1 1 
ATOM   10689 C  CG2 . ILE E 1 205 ? -6.714  -9.377  31.735  1.00 28.43  ? 205 ILE E CG2 1 
ATOM   10690 C  CD1 . ILE E 1 205 ? -6.475  -12.413 31.809  1.00 30.43  ? 205 ILE E CD1 1 
ATOM   10691 N  N   . GLY E 1 206 ? -10.290 -8.592  31.546  1.00 27.02  ? 206 GLY E N   1 
ATOM   10692 C  CA  . GLY E 1 206 ? -10.868 -7.301  31.816  1.00 27.79  ? 206 GLY E CA  1 
ATOM   10693 C  C   . GLY E 1 206 ? -10.143 -6.169  31.105  1.00 27.97  ? 206 GLY E C   1 
ATOM   10694 O  O   . GLY E 1 206 ? -10.450 -5.007  31.358  1.00 29.80  ? 206 GLY E O   1 
ATOM   10695 N  N   . ARG E 1 207 ? -9.196  -6.494  30.229  1.00 26.99  ? 207 ARG E N   1 
ATOM   10696 C  CA  . ARG E 1 207 ? -8.503  -5.457  29.475  1.00 29.73  ? 207 ARG E CA  1 
ATOM   10697 C  C   . ARG E 1 207 ? -8.351  -5.895  28.028  1.00 28.62  ? 207 ARG E C   1 
ATOM   10698 O  O   . ARG E 1 207 ? -8.512  -7.070  27.745  1.00 29.97  ? 207 ARG E O   1 
ATOM   10699 C  CB  . ARG E 1 207 ? -7.096  -5.214  30.010  1.00 31.89  ? 207 ARG E CB  1 
ATOM   10700 C  CG  . ARG E 1 207 ? -7.050  -4.910  31.501  1.00 36.26  ? 207 ARG E CG  1 
ATOM   10701 C  CD  . ARG E 1 207 ? -5.605  -4.658  31.991  1.00 33.71  ? 207 ARG E CD  1 
ATOM   10702 N  NE  . ARG E 1 207 ? -5.099  -3.357  31.536  1.00 32.42  ? 207 ARG E NE  1 
ATOM   10703 C  CZ  . ARG E 1 207 ? -5.246  -2.153  32.127  1.00 33.29  ? 207 ARG E CZ  1 
ATOM   10704 N  NH1 . ARG E 1 207 ? -5.851  -1.987  33.299  1.00 31.11  ? 207 ARG E NH1 1 
ATOM   10705 N  NH2 . ARG E 1 207 ? -4.731  -1.082  31.551  1.00 31.18  ? 207 ARG E NH2 1 
ATOM   10706 N  N   . ARG E 1 208 ? -8.006  -4.957  27.138  1.00 26.10  ? 208 ARG E N   1 
ATOM   10707 C  CA  . ARG E 1 208 ? -7.819  -5.261  25.728  1.00 29.34  ? 208 ARG E CA  1 
ATOM   10708 C  C   . ARG E 1 208 ? -6.464  -5.929  25.544  1.00 30.19  ? 208 ARG E C   1 
ATOM   10709 O  O   . ARG E 1 208 ? -5.478  -5.533  26.143  1.00 31.28  ? 208 ARG E O   1 
ATOM   10710 C  CB  . ARG E 1 208 ? -7.847  -4.032  24.816  1.00 32.24  ? 208 ARG E CB  1 
ATOM   10711 C  CG  . ARG E 1 208 ? -9.099  -3.166  24.881  1.00 36.47  ? 208 ARG E CG  1 
ATOM   10712 C  CD  . ARG E 1 208 ? -10.399 -3.933  24.669  1.00 47.22  ? 208 ARG E CD  1 
ATOM   10713 N  NE  . ARG E 1 208 ? -10.424 -4.555  23.345  1.00 61.20  ? 208 ARG E NE  1 
ATOM   10714 C  CZ  . ARG E 1 208 ? -10.499 -3.917  22.185  1.00 67.40  ? 208 ARG E CZ  1 
ATOM   10715 N  NH1 . ARG E 1 208 ? -10.785 -2.636  22.162  1.00 78.54  ? 208 ARG E NH1 1 
ATOM   10716 N  NH2 . ARG E 1 208 ? -10.343 -4.579  21.051  1.00 58.52  ? 208 ARG E NH2 1 
ATOM   10717 N  N   . LYS E 1 209 ? -6.394  -6.929  24.670  1.00 34.05  ? 209 LYS E N   1 
ATOM   10718 C  CA  . LYS E 1 209 ? -5.180  -7.720  24.541  1.00 31.64  ? 209 LYS E CA  1 
ATOM   10719 C  C   . LYS E 1 209 ? -4.056  -6.894  23.915  1.00 34.49  ? 209 LYS E C   1 
ATOM   10720 O  O   . LYS E 1 209 ? -3.030  -6.709  24.563  1.00 36.78  ? 209 LYS E O   1 
ATOM   10721 C  CB  . LYS E 1 209 ? -5.429  -9.007  23.750  1.00 29.38  ? 209 LYS E CB  1 
ATOM   10722 C  CG  . LYS E 1 209 ? -4.277  -9.938  23.877  1.00 27.33  ? 209 LYS E CG  1 
ATOM   10723 C  CD  . LYS E 1 209 ? -4.555  -11.329 23.344  1.00 31.28  ? 209 LYS E CD  1 
ATOM   10724 C  CE  . LYS E 1 209 ? -3.571  -12.319 23.859  1.00 29.00  ? 209 LYS E CE  1 
ATOM   10725 N  NZ  . LYS E 1 209 ? -3.754  -13.607 23.198  1.00 29.10  ? 209 LYS E NZ  1 
ATOM   10726 N  N   . MET E 1 210 ? -4.294  -6.383  22.690  1.00 37.58  ? 210 MET E N   1 
ATOM   10727 C  CA  . MET E 1 210 ? -3.324  -5.648  21.898  1.00 38.92  ? 210 MET E CA  1 
ATOM   10728 C  C   . MET E 1 210 ? -2.931  -4.329  22.584  1.00 32.47  ? 210 MET E C   1 
ATOM   10729 O  O   . MET E 1 210 ? -1.763  -4.046  22.770  1.00 29.81  ? 210 MET E O   1 
ATOM   10730 C  CB  . MET E 1 210 ? -3.907  -5.401  20.500  1.00 47.36  ? 210 MET E CB  1 
ATOM   10731 C  CG  . MET E 1 210 ? -3.218  -4.323  19.663  1.00 67.02  ? 210 MET E CG  1 
ATOM   10732 S  SD  . MET E 1 210 ? -2.206  -4.891  18.271  1.00 86.12  ? 210 MET E SD  1 
ATOM   10733 C  CE  . MET E 1 210 ? -0.821  -5.722  19.068  1.00 86.01  ? 210 MET E CE  1 
ATOM   10734 N  N   . THR E 1 211 ? -3.906  -3.509  22.976  1.00 29.71  ? 211 THR E N   1 
ATOM   10735 C  CA  . THR E 1 211 ? -3.669  -2.123  23.350  1.00 32.62  ? 211 THR E CA  1 
ATOM   10736 C  C   . THR E 1 211 ? -3.562  -1.963  24.869  1.00 32.63  ? 211 THR E C   1 
ATOM   10737 O  O   . THR E 1 211 ? -3.161  -0.890  25.333  1.00 31.66  ? 211 THR E O   1 
ATOM   10738 C  CB  . THR E 1 211 ? -4.789  -1.232  22.801  1.00 31.64  ? 211 THR E CB  1 
ATOM   10739 O  OG1 . THR E 1 211 ? -6.016  -1.613  23.406  1.00 33.03  ? 211 THR E OG1 1 
ATOM   10740 C  CG2 . THR E 1 211 ? -4.988  -1.416  21.313  1.00 33.47  ? 211 THR E CG2 1 
ATOM   10741 N  N   . ASP E 1 212 ? -3.944  -2.994  25.646  1.00 29.78  ? 212 ASP E N   1 
ATOM   10742 C  CA  . ASP E 1 212 ? -3.857  -2.957  27.107  1.00 28.94  ? 212 ASP E CA  1 
ATOM   10743 C  C   . ASP E 1 212 ? -4.702  -1.852  27.720  1.00 26.38  ? 212 ASP E C   1 
ATOM   10744 O  O   . ASP E 1 212 ? -4.377  -1.388  28.790  1.00 25.68  ? 212 ASP E O   1 
ATOM   10745 C  CB  . ASP E 1 212 ? -2.458  -2.745  27.660  1.00 27.64  ? 212 ASP E CB  1 
ATOM   10746 C  CG  . ASP E 1 212 ? -2.207  -3.211  29.094  1.00 32.61  ? 212 ASP E CG  1 
ATOM   10747 O  OD1 . ASP E 1 212 ? -2.984  -4.128  29.637  1.00 35.82  ? 212 ASP E OD1 1 
ATOM   10748 O  OD2 . ASP E 1 212 ? -1.186  -2.682  29.631  1.00 36.89  ? 212 ASP E OD2 1 
ATOM   10749 N  N   . VAL E 1 213 ? -5.788  -1.446  27.064  1.00 30.14  ? 213 VAL E N   1 
ATOM   10750 C  CA  . VAL E 1 213 ? -6.713  -0.471  27.622  1.00 30.92  ? 213 VAL E CA  1 
ATOM   10751 C  C   . VAL E 1 213 ? -7.802  -1.212  28.390  1.00 29.14  ? 213 VAL E C   1 
ATOM   10752 O  O   . VAL E 1 213 ? -8.372  -2.192  27.911  1.00 28.39  ? 213 VAL E O   1 
ATOM   10753 C  CB  . VAL E 1 213 ? -7.320  0.379   26.494  1.00 33.06  ? 213 VAL E CB  1 
ATOM   10754 C  CG1 . VAL E 1 213 ? -8.374  1.321   27.020  1.00 36.39  ? 213 VAL E CG1 1 
ATOM   10755 C  CG2 . VAL E 1 213 ? -6.252  1.146   25.731  1.00 33.66  ? 213 VAL E CG2 1 
ATOM   10756 N  N   . GLU E 1 214 ? -8.124  -0.720  29.584  1.00 30.72  ? 214 GLU E N   1 
ATOM   10757 C  CA  . GLU E 1 214 ? -9.096  -1.392  30.432  1.00 34.00  ? 214 GLU E CA  1 
ATOM   10758 C  C   . GLU E 1 214 ? -10.458 -1.405  29.759  1.00 34.81  ? 214 GLU E C   1 
ATOM   10759 O  O   . GLU E 1 214 ? -10.794 -0.416  29.149  1.00 43.59  ? 214 GLU E O   1 
ATOM   10760 C  CB  . GLU E 1 214 ? -9.132  -0.606  31.731  1.00 39.71  ? 214 GLU E CB  1 
ATOM   10761 C  CG  . GLU E 1 214 ? -9.816  -1.388  32.838  1.00 46.30  ? 214 GLU E CG  1 
ATOM   10762 C  CD  . GLU E 1 214 ? -9.790  -0.661  34.155  1.00 44.82  ? 214 GLU E CD  1 
ATOM   10763 O  OE1 . GLU E 1 214 ? -9.555  0.579   34.273  1.00 53.59  ? 214 GLU E OE1 1 
ATOM   10764 O  OE2 . GLU E 1 214 ? -10.151 -1.454  35.060  1.00 43.14  ? 214 GLU E OE2 1 
ATOM   10765 N  N   . LEU E 1 215 ? -11.219 -2.507  29.831  1.00 36.27  ? 215 LEU E N   1 
ATOM   10766 C  CA  . LEU E 1 215 ? -12.602 -2.501  29.360  1.00 34.76  ? 215 LEU E CA  1 
ATOM   10767 C  C   . LEU E 1 215 ? -13.414 -1.584  30.264  1.00 40.95  ? 215 LEU E C   1 
ATOM   10768 O  O   . LEU E 1 215 ? -13.182 -1.587  31.466  1.00 39.40  ? 215 LEU E O   1 
ATOM   10769 C  CB  . LEU E 1 215 ? -13.225 -3.892  29.435  1.00 35.57  ? 215 LEU E CB  1 
ATOM   10770 C  CG  . LEU E 1 215 ? -12.613 -5.003  28.587  1.00 34.53  ? 215 LEU E CG  1 
ATOM   10771 C  CD1 . LEU E 1 215 ? -13.435 -6.296  28.673  1.00 31.55  ? 215 LEU E CD1 1 
ATOM   10772 C  CD2 . LEU E 1 215 ? -12.579 -4.471  27.194  1.00 39.10  ? 215 LEU E CD2 1 
ATOM   10773 N  N   . SER E 1 216 ? -14.371 -0.829  29.700  1.00 53.55  ? 216 SER E N   1 
ATOM   10774 C  CA  . SER E 1 216 ? -15.191 0.096   30.488  1.00 59.50  ? 216 SER E CA  1 
ATOM   10775 C  C   . SER E 1 216 ? -16.072 -0.675  31.469  1.00 77.20  ? 216 SER E C   1 
ATOM   10776 O  O   . SER E 1 216 ? -16.416 -1.832  31.209  1.00 72.34  ? 216 SER E O   1 
ATOM   10777 C  CB  . SER E 1 216 ? -16.041 1.001   29.634  1.00 53.30  ? 216 SER E CB  1 
ATOM   10778 O  OG  . SER E 1 216 ? -16.924 0.243   28.827  1.00 52.91  ? 216 SER E OG  1 
ATOM   10779 N  N   . ASP E 1 217 ? -16.432 -0.018  32.584  1.00 85.17  ? 217 ASP E N   1 
ATOM   10780 C  CA  . ASP E 1 217 ? -17.206 -0.638  33.657  1.00 78.00  ? 217 ASP E CA  1 
ATOM   10781 C  C   . ASP E 1 217 ? -18.551 -1.131  33.134  1.00 64.51  ? 217 ASP E C   1 
ATOM   10782 O  O   . ASP E 1 217 ? -19.064 -2.122  33.628  1.00 51.08  ? 217 ASP E O   1 
ATOM   10783 C  CB  . ASP E 1 217 ? -17.438 0.317   34.814  1.00 82.20  ? 217 ASP E CB  1 
ATOM   10784 C  CG  . ASP E 1 217 ? -16.176 0.837   35.460  1.00 83.19  ? 217 ASP E CG  1 
ATOM   10785 O  OD1 . ASP E 1 217 ? -15.348 -0.006  35.871  1.00 85.14  ? 217 ASP E OD1 1 
ATOM   10786 O  OD2 . ASP E 1 217 ? -16.054 2.069   35.528  1.00 93.63  ? 217 ASP E OD2 1 
ATOM   10787 N  N   . ASP E 1 218 ? -19.083 -0.452  32.110  1.00 65.50  ? 218 ASP E N   1 
ATOM   10788 C  CA  . ASP E 1 218 ? -20.341 -0.803  31.479  1.00 63.16  ? 218 ASP E CA  1 
ATOM   10789 C  C   . ASP E 1 218 ? -20.203 -2.155  30.742  1.00 65.88  ? 218 ASP E C   1 
ATOM   10790 O  O   . ASP E 1 218 ? -21.218 -2.742  30.431  1.00 75.94  ? 218 ASP E O   1 
ATOM   10791 C  CB  . ASP E 1 218 ? -20.912 0.399   30.705  1.00 45.69  ? 218 ASP E CB  1 
ATOM   10792 N  N   . VAL E 1 219 ? -19.004 -2.703  30.468  1.00 63.46  ? 219 VAL E N   1 
ATOM   10793 C  CA  . VAL E 1 219 ? -18.926 -3.945  29.697  1.00 53.18  ? 219 VAL E CA  1 
ATOM   10794 C  C   . VAL E 1 219 ? -18.011 -4.984  30.369  1.00 50.24  ? 219 VAL E C   1 
ATOM   10795 O  O   . VAL E 1 219 ? -17.902 -6.146  29.954  1.00 40.94  ? 219 VAL E O   1 
ATOM   10796 C  CB  . VAL E 1 219 ? -18.509 -3.686  28.227  1.00 46.35  ? 219 VAL E CB  1 
ATOM   10797 C  CG1 . VAL E 1 219 ? -18.940 -2.325  27.661  1.00 45.85  ? 219 VAL E CG1 1 
ATOM   10798 C  CG2 . VAL E 1 219 ? -17.025 -3.851  28.022  1.00 44.69  ? 219 VAL E CG2 1 
ATOM   10799 N  N   . LYS E 1 220 ? -17.279 -4.594  31.406  1.00 46.79  ? 220 LYS E N   1 
ATOM   10800 C  CA  . LYS E 1 220 ? -16.316 -5.520  31.973  1.00 44.41  ? 220 LYS E CA  1 
ATOM   10801 C  C   . LYS E 1 220 ? -17.071 -6.518  32.830  1.00 37.73  ? 220 LYS E C   1 
ATOM   10802 O  O   . LYS E 1 220 ? -17.683 -6.115  33.803  1.00 39.24  ? 220 LYS E O   1 
ATOM   10803 C  CB  . LYS E 1 220 ? -15.333 -4.722  32.836  1.00 45.01  ? 220 LYS E CB  1 
ATOM   10804 C  CG  . LYS E 1 220 ? -14.228 -5.507  33.535  1.00 40.04  ? 220 LYS E CG  1 
ATOM   10805 C  CD  . LYS E 1 220 ? -13.477 -4.698  34.587  1.00 39.33  ? 220 LYS E CD  1 
ATOM   10806 C  CE  . LYS E 1 220 ? -13.582 -3.207  34.375  1.00 49.48  ? 220 LYS E CE  1 
ATOM   10807 N  NZ  . LYS E 1 220 ? -12.445 -2.490  34.941  1.00 53.17  ? 220 LYS E NZ  1 
ATOM   10808 N  N   . PRO E 1 221 ? -17.051 -7.827  32.540  1.00 35.26  ? 221 PRO E N   1 
ATOM   10809 C  CA  . PRO E 1 221 ? -17.746 -8.819  33.377  1.00 32.51  ? 221 PRO E CA  1 
ATOM   10810 C  C   . PRO E 1 221 ? -17.346 -8.780  34.843  1.00 35.34  ? 221 PRO E C   1 
ATOM   10811 O  O   . PRO E 1 221 ? -16.214 -8.415  35.177  1.00 42.27  ? 221 PRO E O   1 
ATOM   10812 C  CB  . PRO E 1 221 ? -17.371 -10.181 32.763  1.00 34.47  ? 221 PRO E CB  1 
ATOM   10813 C  CG  . PRO E 1 221 ? -16.975 -9.845  31.320  1.00 38.15  ? 221 PRO E CG  1 
ATOM   10814 C  CD  . PRO E 1 221 ? -16.394 -8.426  31.374  1.00 38.80  ? 221 PRO E CD  1 
ATOM   10815 N  N   . ALA E 1 222 ? -18.295 -9.135  35.722  1.00 36.82  ? 222 ALA E N   1 
ATOM   10816 C  CA  . ALA E 1 222 ? -18.040 -9.124  37.158  1.00 37.33  ? 222 ALA E CA  1 
ATOM   10817 C  C   . ALA E 1 222 ? -17.122 -10.287 37.568  1.00 34.70  ? 222 ALA E C   1 
ATOM   10818 O  O   . ALA E 1 222 ? -16.555 -10.247 38.653  1.00 41.39  ? 222 ALA E O   1 
ATOM   10819 C  CB  . ALA E 1 222 ? -19.324 -9.164  37.934  1.00 37.20  ? 222 ALA E CB  1 
ATOM   10820 N  N   . ASP E 1 223 ? -16.970 -11.310 36.722  1.00 29.49  ? 223 ASP E N   1 
ATOM   10821 C  CA  . ASP E 1 223 ? -16.090 -12.415 37.038  1.00 33.53  ? 223 ASP E CA  1 
ATOM   10822 C  C   . ASP E 1 223 ? -14.777 -12.314 36.250  1.00 40.82  ? 223 ASP E C   1 
ATOM   10823 O  O   . ASP E 1 223 ? -14.002 -13.283 36.183  1.00 35.86  ? 223 ASP E O   1 
ATOM   10824 C  CB  . ASP E 1 223 ? -16.786 -13.757 36.891  1.00 33.63  ? 223 ASP E CB  1 
ATOM   10825 C  CG  . ASP E 1 223 ? -17.226 -14.121 35.492  1.00 33.73  ? 223 ASP E CG  1 
ATOM   10826 O  OD1 . ASP E 1 223 ? -17.266 -13.207 34.636  1.00 31.08  ? 223 ASP E OD1 1 
ATOM   10827 O  OD2 . ASP E 1 223 ? -17.513 -15.315 35.294  1.00 37.87  ? 223 ASP E OD2 1 
ATOM   10828 N  N   . SER E 1 224 ? -14.502 -11.124 35.691  1.00 43.14  ? 224 SER E N   1 
ATOM   10829 C  CA  . SER E 1 224 ? -13.205 -10.865 35.076  1.00 39.60  ? 224 SER E CA  1 
ATOM   10830 C  C   . SER E 1 224 ? -12.172 -10.658 36.185  1.00 38.52  ? 224 SER E C   1 
ATOM   10831 O  O   . SER E 1 224 ? -12.529 -10.275 37.300  1.00 35.51  ? 224 SER E O   1 
ATOM   10832 C  CB  . SER E 1 224 ? -13.253 -9.691  34.121  1.00 34.66  ? 224 SER E CB  1 
ATOM   10833 O  OG  . SER E 1 224 ? -13.409 -8.501  34.853  1.00 31.11  ? 224 SER E OG  1 
ATOM   10834 N  N   . HIS E 1 225 ? -10.898 -10.911 35.849  1.00 40.00  ? 225 HIS E N   1 
ATOM   10835 C  CA  . HIS E 1 225 ? -9.808  -10.914 36.822  1.00 36.89  ? 225 HIS E CA  1 
ATOM   10836 C  C   . HIS E 1 225 ? -9.620  -9.520  37.420  1.00 32.55  ? 225 HIS E C   1 
ATOM   10837 O  O   . HIS E 1 225 ? -9.430  -9.386  38.621  1.00 30.31  ? 225 HIS E O   1 
ATOM   10838 C  CB  . HIS E 1 225 ? -8.540  -11.466 36.170  1.00 37.60  ? 225 HIS E CB  1 
ATOM   10839 C  CG  . HIS E 1 225 ? -7.333  -11.413 37.047  1.00 39.59  ? 225 HIS E CG  1 
ATOM   10840 N  ND1 . HIS E 1 225 ? -7.255  -12.145 38.197  1.00 37.62  ? 225 HIS E ND1 1 
ATOM   10841 C  CD2 . HIS E 1 225 ? -6.164  -10.768 36.955  1.00 37.98  ? 225 HIS E CD2 1 
ATOM   10842 C  CE1 . HIS E 1 225 ? -6.069  -11.947 38.754  1.00 39.69  ? 225 HIS E CE1 1 
ATOM   10843 N  NE2 . HIS E 1 225 ? -5.389  -11.125 38.009  1.00 36.10  ? 225 HIS E NE2 1 
ATOM   10844 N  N   . VAL E 1 226 ? -9.708  -8.493  36.571  1.00 31.97  ? 226 VAL E N   1 
ATOM   10845 C  CA  . VAL E 1 226 ? -9.496  -7.119  37.003  1.00 33.72  ? 226 VAL E CA  1 
ATOM   10846 C  C   . VAL E 1 226 ? -10.657 -6.653  37.885  1.00 31.62  ? 226 VAL E C   1 
ATOM   10847 O  O   . VAL E 1 226 ? -10.472 -5.827  38.791  1.00 30.06  ? 226 VAL E O   1 
ATOM   10848 C  CB  . VAL E 1 226 ? -9.322  -6.211  35.761  1.00 35.47  ? 226 VAL E CB  1 
ATOM   10849 C  CG1 . VAL E 1 226 ? -9.633  -4.756  36.050  1.00 34.95  ? 226 VAL E CG1 1 
ATOM   10850 C  CG2 . VAL E 1 226 ? -7.924  -6.310  35.187  1.00 38.66  ? 226 VAL E CG2 1 
ATOM   10851 N  N   . ALA E 1 227 ? -11.858 -7.167  37.589  1.00 30.12  ? 227 ALA E N   1 
ATOM   10852 C  CA  . ALA E 1 227 ? -13.027 -6.845  38.387  1.00 29.56  ? 227 ALA E CA  1 
ATOM   10853 C  C   . ALA E 1 227 ? -12.840 -7.387  39.796  1.00 31.87  ? 227 ALA E C   1 
ATOM   10854 O  O   . ALA E 1 227 ? -12.963 -6.644  40.749  1.00 35.49  ? 227 ALA E O   1 
ATOM   10855 C  CB  . ALA E 1 227 ? -14.273 -7.445  37.766  1.00 31.55  ? 227 ALA E CB  1 
ATOM   10856 N  N   . LEU E 1 228 ? -12.501 -8.667  39.928  1.00 30.08  ? 228 LEU E N   1 
ATOM   10857 C  CA  . LEU E 1 228 ? -12.428 -9.286  41.236  1.00 36.19  ? 228 LEU E CA  1 
ATOM   10858 C  C   . LEU E 1 228 ? -11.204 -8.864  42.047  1.00 39.02  ? 228 LEU E C   1 
ATOM   10859 O  O   . LEU E 1 228 ? -11.218 -9.069  43.253  1.00 43.59  ? 228 LEU E O   1 
ATOM   10860 C  CB  . LEU E 1 228 ? -12.432 -10.797 41.088  1.00 36.95  ? 228 LEU E CB  1 
ATOM   10861 C  CG  . LEU E 1 228 ? -13.753 -11.388 40.621  1.00 46.04  ? 228 LEU E CG  1 
ATOM   10862 C  CD1 . LEU E 1 228 ? -13.541 -12.841 40.215  1.00 49.09  ? 228 LEU E CD1 1 
ATOM   10863 C  CD2 . LEU E 1 228 ? -14.737 -11.264 41.775  1.00 48.14  ? 228 LEU E CD2 1 
ATOM   10864 N  N   . THR E 1 229 ? -10.129 -8.350  41.423  1.00 39.43  ? 229 THR E N   1 
ATOM   10865 C  CA  . THR E 1 229 ? -8.947  -7.995  42.191  1.00 36.16  ? 229 THR E CA  1 
ATOM   10866 C  C   . THR E 1 229 ? -8.904  -6.499  42.447  1.00 37.64  ? 229 THR E C   1 
ATOM   10867 O  O   . THR E 1 229 ? -7.909  -6.042  43.005  1.00 39.45  ? 229 THR E O   1 
ATOM   10868 C  CB  . THR E 1 229 ? -7.671  -8.485  41.518  1.00 35.72  ? 229 THR E CB  1 
ATOM   10869 O  OG1 . THR E 1 229 ? -7.618  -7.909  40.217  1.00 34.17  ? 229 THR E OG1 1 
ATOM   10870 C  CG2 . THR E 1 229 ? -7.589  -10.004 41.466  1.00 37.62  ? 229 THR E CG2 1 
ATOM   10871 N  N   . SER E 1 230 ? -9.954  -5.759  42.051  1.00 42.96  ? 230 SER E N   1 
ATOM   10872 C  CA  . SER E 1 230 ? -10.140 -4.379  42.490  1.00 50.57  ? 230 SER E CA  1 
ATOM   10873 C  C   . SER E 1 230 ? -11.002 -4.372  43.748  1.00 49.64  ? 230 SER E C   1 
ATOM   10874 O  O   . SER E 1 230 ? -12.124 -4.831  43.726  1.00 49.94  ? 230 SER E O   1 
ATOM   10875 C  CB  . SER E 1 230 ? -10.761 -3.538  41.426  1.00 53.70  ? 230 SER E CB  1 
ATOM   10876 O  OG  . SER E 1 230 ? -9.931  -3.481  40.270  1.00 65.32  ? 230 SER E OG  1 
ATOM   10877 N  N   . VAL E 1 231 ? -10.468 -3.898  44.860  1.00 52.60  ? 231 VAL E N   1 
ATOM   10878 C  CA  . VAL E 1 231 ? -11.165 -3.916  46.134  1.00 57.51  ? 231 VAL E CA  1 
ATOM   10879 C  C   . VAL E 1 231 ? -10.963 -2.534  46.752  1.00 61.87  ? 231 VAL E C   1 
ATOM   10880 O  O   . VAL E 1 231 ? -9.858  -1.961  46.654  1.00 52.76  ? 231 VAL E O   1 
ATOM   10881 C  CB  . VAL E 1 231 ? -10.637 -5.000  47.095  1.00 69.58  ? 231 VAL E CB  1 
ATOM   10882 C  CG1 . VAL E 1 231 ? -11.600 -5.174  48.266  1.00 79.09  ? 231 VAL E CG1 1 
ATOM   10883 C  CG2 . VAL E 1 231 ? -10.346 -6.338  46.420  1.00 62.03  ? 231 VAL E CG2 1 
ATOM   10884 N  N   . THR E 1 232 ? -12.024 -1.999  47.386  1.00 56.67  ? 232 THR E N   1 
ATOM   10885 C  CA  . THR E 1 232 ? -11.885 -0.711  48.064  1.00 64.95  ? 232 THR E CA  1 
ATOM   10886 C  C   . THR E 1 232 ? -11.940 -0.926  49.577  1.00 65.72  ? 232 THR E C   1 
ATOM   10887 O  O   . THR E 1 232 ? -12.590 -1.851  50.052  1.00 56.88  ? 232 THR E O   1 
ATOM   10888 C  CB  . THR E 1 232 ? -12.907 0.314   47.590  1.00 58.59  ? 232 THR E CB  1 
ATOM   10889 O  OG1 . THR E 1 232 ? -14.055 -0.494  47.755  1.00 58.03  ? 232 THR E OG1 1 
ATOM   10890 C  CG2 . THR E 1 232 ? -12.744 0.759   46.148  1.00 54.67  ? 232 THR E CG2 1 
ATOM   10891 N  N   . GLY E 1 233 ? -11.135 -0.136  50.295  1.00 84.04  ? 233 GLY E N   1 
ATOM   10892 C  CA  . GLY E 1 233 ? -10.983 -0.348  51.719  1.00 93.50  ? 233 GLY E CA  1 
ATOM   10893 C  C   . GLY E 1 233 ? -12.144 0.281   52.471  1.00 106.51 ? 233 GLY E C   1 
ATOM   10894 O  O   . GLY E 1 233 ? -12.909 1.074   51.903  1.00 88.89  ? 233 GLY E O   1 
ATOM   10895 N  N   . PRO E 1 234 ? -12.243 0.013   53.796  1.00 115.91 ? 234 PRO E N   1 
ATOM   10896 C  CA  . PRO E 1 234 ? -12.898 0.951   54.717  1.00 108.90 ? 234 PRO E CA  1 
ATOM   10897 C  C   . PRO E 1 234 ? -12.703 2.444   54.413  1.00 102.29 ? 234 PRO E C   1 
ATOM   10898 O  O   . PRO E 1 234 ? -13.689 3.167   54.400  1.00 85.27  ? 234 PRO E O   1 
ATOM   10899 C  CB  . PRO E 1 234 ? -12.273 0.507   56.074  1.00 118.79 ? 234 PRO E CB  1 
ATOM   10900 C  CG  . PRO E 1 234 ? -12.030 -0.998  55.915  1.00 112.52 ? 234 PRO E CG  1 
ATOM   10901 C  CD  . PRO E 1 234 ? -11.714 -1.203  54.447  1.00 106.55 ? 234 PRO E CD  1 
ATOM   10902 N  N   . ASP E 1 235 ? -11.472 2.887   54.079  1.00 111.53 ? 235 ASP E N   1 
ATOM   10903 C  CA  . ASP E 1 235 ? -11.167 4.279   53.755  1.00 101.51 ? 235 ASP E CA  1 
ATOM   10904 C  C   . ASP E 1 235 ? -11.880 4.775   52.486  1.00 98.87  ? 235 ASP E C   1 
ATOM   10905 O  O   . ASP E 1 235 ? -11.847 5.973   52.225  1.00 76.75  ? 235 ASP E O   1 
ATOM   10906 C  CB  . ASP E 1 235 ? -9.658  4.540   53.654  1.00 77.63  ? 235 ASP E CB  1 
ATOM   10907 N  N   . GLY E 1 236 ? -12.463 3.889   51.649  1.00 107.46 ? 236 GLY E N   1 
ATOM   10908 C  CA  . GLY E 1 236 ? -12.987 4.287   50.345  1.00 96.30  ? 236 GLY E CA  1 
ATOM   10909 C  C   . GLY E 1 236 ? -11.918 4.316   49.236  1.00 96.39  ? 236 GLY E C   1 
ATOM   10910 O  O   . GLY E 1 236 ? -12.224 4.219   48.047  1.00 79.96  ? 236 GLY E O   1 
ATOM   10911 N  N   . SER E 1 237 ? -10.643 4.433   49.650  1.00 99.50  ? 237 SER E N   1 
ATOM   10912 C  CA  . SER E 1 237 ? -9.469  4.280   48.813  1.00 78.04  ? 237 SER E CA  1 
ATOM   10913 C  C   . SER E 1 237 ? -9.336  2.831   48.316  1.00 73.75  ? 237 SER E C   1 
ATOM   10914 O  O   . SER E 1 237 ? -9.728  1.840   48.954  1.00 70.50  ? 237 SER E O   1 
ATOM   10915 C  CB  . SER E 1 237 ? -8.239  4.727   49.596  1.00 63.40  ? 237 SER E CB  1 
ATOM   10916 N  N   . ASP E 1 238 ? -8.776  2.725   47.117  1.00 74.07  ? 238 ASP E N   1 
ATOM   10917 C  CA  . ASP E 1 238 ? -8.430  1.432   46.522  1.00 72.78  ? 238 ASP E CA  1 
ATOM   10918 C  C   . ASP E 1 238 ? -7.349  0.737   47.356  1.00 60.43  ? 238 ASP E C   1 
ATOM   10919 O  O   . ASP E 1 238 ? -6.415  1.391   47.818  1.00 57.62  ? 238 ASP E O   1 
ATOM   10920 C  CB  . ASP E 1 238 ? -7.969  1.615   45.088  1.00 66.57  ? 238 ASP E CB  1 
ATOM   10921 C  CG  . ASP E 1 238 ? -9.012  2.243   44.181  1.00 66.49  ? 238 ASP E CG  1 
ATOM   10922 O  OD1 . ASP E 1 238 ? -10.164 1.761   44.195  1.00 62.01  ? 238 ASP E OD1 1 
ATOM   10923 O  OD2 . ASP E 1 238 ? -8.662  3.209   43.478  1.00 84.69  ? 238 ASP E OD2 1 
ATOM   10924 N  N   . LEU E 1 239 ? -7.478  -0.579  47.566  1.00 46.72  ? 239 LEU E N   1 
ATOM   10925 C  CA  . LEU E 1 239 ? -6.421  -1.352  48.195  1.00 48.91  ? 239 LEU E CA  1 
ATOM   10926 C  C   . LEU E 1 239 ? -5.446  -1.913  47.158  1.00 42.33  ? 239 LEU E C   1 
ATOM   10927 O  O   . LEU E 1 239 ? -5.886  -2.603  46.253  1.00 45.48  ? 239 LEU E O   1 
ATOM   10928 C  CB  . LEU E 1 239 ? -7.088  -2.482  48.971  1.00 58.93  ? 239 LEU E CB  1 
ATOM   10929 C  CG  . LEU E 1 239 ? -7.864  -2.087  50.228  1.00 60.65  ? 239 LEU E CG  1 
ATOM   10930 C  CD1 . LEU E 1 239 ? -8.393  -3.403  50.807  1.00 72.68  ? 239 LEU E CD1 1 
ATOM   10931 C  CD2 . LEU E 1 239 ? -7.048  -1.282  51.211  1.00 48.96  ? 239 LEU E CD2 1 
ATOM   10932 N  N   . GLU E 1 240 ? -4.140  -1.682  47.311  1.00 37.60  ? 240 GLU E N   1 
ATOM   10933 C  CA  . GLU E 1 240 ? -3.204  -2.041  46.254  1.00 40.04  ? 240 GLU E CA  1 
ATOM   10934 C  C   . GLU E 1 240 ? -2.169  -3.060  46.720  1.00 36.84  ? 240 GLU E C   1 
ATOM   10935 O  O   . GLU E 1 240 ? -1.796  -3.051  47.881  1.00 36.59  ? 240 GLU E O   1 
ATOM   10936 C  CB  . GLU E 1 240 ? -2.519  -0.775  45.762  1.00 46.24  ? 240 GLU E CB  1 
ATOM   10937 C  CG  . GLU E 1 240 ? -3.513  0.319   45.391  1.00 45.01  ? 240 GLU E CG  1 
ATOM   10938 C  CD  . GLU E 1 240 ? -2.842  1.469   44.732  1.00 49.70  ? 240 GLU E CD  1 
ATOM   10939 O  OE1 . GLU E 1 240 ? -2.091  2.245   45.366  1.00 57.47  ? 240 GLU E OE1 1 
ATOM   10940 O  OE2 . GLU E 1 240 ? -3.073  1.496   43.535  1.00 53.25  ? 240 GLU E OE2 1 
ATOM   10941 N  N   . ILE E 1 241 ? -1.713  -3.921  45.802  1.00 32.96  ? 241 ILE E N   1 
ATOM   10942 C  CA  . ILE E 1 241 ? -0.505  -4.710  46.039  1.00 34.18  ? 241 ILE E CA  1 
ATOM   10943 C  C   . ILE E 1 241 ? 0.541   -4.436  44.953  1.00 32.69  ? 241 ILE E C   1 
ATOM   10944 O  O   . ILE E 1 241 ? 0.272   -3.808  43.947  1.00 34.22  ? 241 ILE E O   1 
ATOM   10945 C  CB  . ILE E 1 241 ? -0.809  -6.216  46.157  1.00 31.33  ? 241 ILE E CB  1 
ATOM   10946 C  CG1 . ILE E 1 241 ? -1.287  -6.786  44.859  1.00 29.78  ? 241 ILE E CG1 1 
ATOM   10947 C  CG2 . ILE E 1 241 ? -1.818  -6.460  47.276  1.00 35.97  ? 241 ILE E CG2 1 
ATOM   10948 C  CD1 . ILE E 1 241 ? -1.555  -8.275  44.884  1.00 31.17  ? 241 ILE E CD1 1 
ATOM   10949 N  N   . LEU E 1 242 ? 1.754   -4.927  45.165  1.00 31.14  ? 242 LEU E N   1 
ATOM   10950 C  CA  . LEU E 1 242 ? 2.780   -4.837  44.152  1.00 28.90  ? 242 LEU E CA  1 
ATOM   10951 C  C   . LEU E 1 242 ? 3.090   -6.239  43.681  1.00 26.73  ? 242 LEU E C   1 
ATOM   10952 O  O   . LEU E 1 242 ? 3.534   -7.025  44.480  1.00 24.22  ? 242 LEU E O   1 
ATOM   10953 C  CB  . LEU E 1 242 ? 4.021   -4.199  44.736  1.00 28.87  ? 242 LEU E CB  1 
ATOM   10954 C  CG  . LEU E 1 242 ? 5.150   -3.957  43.744  1.00 31.37  ? 242 LEU E CG  1 
ATOM   10955 C  CD1 . LEU E 1 242 ? 4.735   -2.897  42.798  1.00 31.14  ? 242 LEU E CD1 1 
ATOM   10956 C  CD2 . LEU E 1 242 ? 6.422   -3.452  44.372  1.00 32.35  ? 242 LEU E CD2 1 
ATOM   10957 N  N   . ARG E 1 243 ? 2.906   -6.511  42.392  1.00 26.59  ? 243 ARG E N   1 
ATOM   10958 C  CA  . ARG E 1 243 ? 3.114   -7.840  41.844  1.00 25.63  ? 243 ARG E CA  1 
ATOM   10959 C  C   . ARG E 1 243 ? 4.325   -7.863  40.921  1.00 23.91  ? 243 ARG E C   1 
ATOM   10960 O  O   . ARG E 1 243 ? 4.674   -6.850  40.364  1.00 23.47  ? 243 ARG E O   1 
ATOM   10961 C  CB  . ARG E 1 243 ? 1.933   -8.188  40.945  1.00 29.58  ? 243 ARG E CB  1 
ATOM   10962 C  CG  . ARG E 1 243 ? 0.642   -8.373  41.711  1.00 31.85  ? 243 ARG E CG  1 
ATOM   10963 C  CD  . ARG E 1 243 ? -0.533  -8.395  40.752  1.00 32.05  ? 243 ARG E CD  1 
ATOM   10964 N  NE  . ARG E 1 243 ? -0.724  -7.049  40.193  1.00 29.15  ? 243 ARG E NE  1 
ATOM   10965 C  CZ  . ARG E 1 243 ? -0.735  -6.779  38.900  1.00 28.41  ? 243 ARG E CZ  1 
ATOM   10966 N  NH1 . ARG E 1 243 ? -0.647  -7.790  37.998  1.00 26.07  ? 243 ARG E NH1 1 
ATOM   10967 N  NH2 . ARG E 1 243 ? -0.893  -5.494  38.565  1.00 27.01  ? 243 ARG E NH2 1 
ATOM   10968 N  N   . ASP E 1 244 ? 4.941   -9.021  40.738  1.00 25.32  ? 244 ASP E N   1 
ATOM   10969 C  CA  . ASP E 1 244 ? 5.993   -9.166  39.757  1.00 27.98  ? 244 ASP E CA  1 
ATOM   10970 C  C   . ASP E 1 244 ? 5.918   -10.568 39.149  1.00 30.64  ? 244 ASP E C   1 
ATOM   10971 O  O   . ASP E 1 244 ? 6.871   -11.331 39.202  1.00 29.77  ? 244 ASP E O   1 
ATOM   10972 C  CB  . ASP E 1 244 ? 7.347   -8.779  40.326  1.00 31.63  ? 244 ASP E CB  1 
ATOM   10973 C  CG  . ASP E 1 244 ? 8.372   -8.396  39.272  1.00 33.11  ? 244 ASP E CG  1 
ATOM   10974 O  OD1 . ASP E 1 244 ? 7.958   -8.283  38.114  1.00 31.47  ? 244 ASP E OD1 1 
ATOM   10975 O  OD2 . ASP E 1 244 ? 9.556   -8.256  39.608  1.00 34.10  ? 244 ASP E OD2 1 
ATOM   10976 N  N   . ASN E 1 245 ? 4.767   -10.861 38.538  1.00 28.15  ? 245 ASN E N   1 
ATOM   10977 C  CA  . ASN E 1 245 ? 4.514   -12.159 37.954  1.00 30.99  ? 245 ASN E CA  1 
ATOM   10978 C  C   . ASN E 1 245 ? 5.539   -12.447 36.865  1.00 29.99  ? 245 ASN E C   1 
ATOM   10979 O  O   . ASN E 1 245 ? 5.849   -11.575 36.044  1.00 28.98  ? 245 ASN E O   1 
ATOM   10980 C  CB  . ASN E 1 245 ? 3.118   -12.226 37.346  1.00 36.06  ? 245 ASN E CB  1 
ATOM   10981 C  CG  . ASN E 1 245 ? 2.060   -11.895 38.364  1.00 38.89  ? 245 ASN E CG  1 
ATOM   10982 O  OD1 . ASN E 1 245 ? 2.371   -11.983 39.568  1.00 35.41  ? 245 ASN E OD1 1 
ATOM   10983 N  ND2 . ASN E 1 245 ? 0.865   -11.512 37.899  1.00 38.70  ? 245 ASN E ND2 1 
ATOM   10984 N  N   . MET E 1 246 ? 5.981   -13.706 36.816  1.00 24.87  ? 246 MET E N   1 
ATOM   10985 C  CA  . MET E 1 246 ? 6.970   -14.136 35.854  1.00 26.52  ? 246 MET E CA  1 
ATOM   10986 C  C   . MET E 1 246 ? 6.538   -15.426 35.200  1.00 24.59  ? 246 MET E C   1 
ATOM   10987 O  O   . MET E 1 246 ? 6.267   -16.410 35.865  1.00 29.13  ? 246 MET E O   1 
ATOM   10988 C  CB  . MET E 1 246 ? 8.331   -14.429 36.510  1.00 29.59  ? 246 MET E CB  1 
ATOM   10989 C  CG  . MET E 1 246 ? 9.026   -13.202 37.091  1.00 33.15  ? 246 MET E CG  1 
ATOM   10990 S  SD  . MET E 1 246 ? 9.430   -11.967 35.833  1.00 34.21  ? 246 MET E SD  1 
ATOM   10991 C  CE  . MET E 1 246 ? 10.835  -12.833 35.131  1.00 35.10  ? 246 MET E CE  1 
ATOM   10992 N  N   . PRO E 1 247 ? 6.542   -15.474 33.869  1.00 23.67  ? 247 PRO E N   1 
ATOM   10993 C  CA  . PRO E 1 247 ? 6.417   -16.726 33.141  1.00 22.95  ? 247 PRO E CA  1 
ATOM   10994 C  C   . PRO E 1 247 ? 7.574   -17.664 33.403  1.00 21.80  ? 247 PRO E C   1 
ATOM   10995 O  O   . PRO E 1 247 ? 8.698   -17.254 33.620  1.00 20.34  ? 247 PRO E O   1 
ATOM   10996 C  CB  . PRO E 1 247 ? 6.440   -16.313 31.676  1.00 26.24  ? 247 PRO E CB  1 
ATOM   10997 C  CG  . PRO E 1 247 ? 6.167   -14.834 31.690  1.00 27.98  ? 247 PRO E CG  1 
ATOM   10998 C  CD  . PRO E 1 247 ? 6.645   -14.301 33.005  1.00 26.74  ? 247 PRO E CD  1 
ATOM   10999 N  N   . PHE E 1 248 ? 7.298   -18.949 33.270  1.00 24.05  ? 248 PHE E N   1 
ATOM   11000 C  CA  . PHE E 1 248 ? 8.318   -19.983 33.290  1.00 24.12  ? 248 PHE E CA  1 
ATOM   11001 C  C   . PHE E 1 248 ? 7.751   -21.173 32.532  1.00 24.38  ? 248 PHE E C   1 
ATOM   11002 O  O   . PHE E 1 248 ? 6.561   -21.250 32.255  1.00 22.85  ? 248 PHE E O   1 
ATOM   11003 C  CB  . PHE E 1 248 ? 8.628   -20.358 34.743  1.00 25.00  ? 248 PHE E CB  1 
ATOM   11004 C  CG  . PHE E 1 248 ? 7.482   -21.094 35.437  1.00 25.38  ? 248 PHE E CG  1 
ATOM   11005 C  CD1 . PHE E 1 248 ? 7.380   -22.478 35.356  1.00 22.61  ? 248 PHE E CD1 1 
ATOM   11006 C  CD2 . PHE E 1 248 ? 6.459   -20.406 36.072  1.00 26.11  ? 248 PHE E CD2 1 
ATOM   11007 C  CE1 . PHE E 1 248 ? 6.364   -23.169 35.980  1.00 22.24  ? 248 PHE E CE1 1 
ATOM   11008 C  CE2 . PHE E 1 248 ? 5.451   -21.111 36.727  1.00 25.28  ? 248 PHE E CE2 1 
ATOM   11009 C  CZ  . PHE E 1 248 ? 5.401   -22.485 36.654  1.00 24.34  ? 248 PHE E CZ  1 
ATOM   11010 N  N   . GLY E 1 249 ? 8.611   -22.114 32.212  1.00 22.27  ? 249 GLY E N   1 
ATOM   11011 C  CA  . GLY E 1 249 ? 8.078   -23.341 31.690  1.00 23.39  ? 249 GLY E CA  1 
ATOM   11012 C  C   . GLY E 1 249 ? 9.136   -24.275 31.125  1.00 25.29  ? 249 GLY E C   1 
ATOM   11013 O  O   . GLY E 1 249 ? 10.338  -24.019 31.137  1.00 24.22  ? 249 GLY E O   1 
ATOM   11014 N  N   . SER E 1 250 ? 8.612   -25.340 30.530  1.00 28.53  ? 250 SER E N   1 
ATOM   11015 C  CA  . SER E 1 250 ? 9.405   -26.319 29.823  1.00 29.35  ? 250 SER E CA  1 
ATOM   11016 C  C   . SER E 1 250 ? 8.596   -26.842 28.635  1.00 33.45  ? 250 SER E C   1 
ATOM   11017 O  O   . SER E 1 250 ? 7.457   -27.264 28.791  1.00 33.99  ? 250 SER E O   1 
ATOM   11018 C  CB  . SER E 1 250 ? 9.773   -27.361 30.810  1.00 31.93  ? 250 SER E CB  1 
ATOM   11019 O  OG  . SER E 1 250 ? 9.905   -28.620 30.191  1.00 36.40  ? 250 SER E OG  1 
ATOM   11020 N  N   . VAL E 1 251 ? 9.152   -26.775 27.429  1.00 37.13  ? 251 VAL E N   1 
ATOM   11021 C  CA  . VAL E 1 251 ? 8.372   -27.134 26.251  1.00 42.56  ? 251 VAL E CA  1 
ATOM   11022 C  C   . VAL E 1 251 ? 8.248   -28.653 26.145  1.00 38.05  ? 251 VAL E C   1 
ATOM   11023 O  O   . VAL E 1 251 ? 7.203   -29.165 25.773  1.00 46.42  ? 251 VAL E O   1 
ATOM   11024 C  CB  . VAL E 1 251 ? 8.904   -26.496 24.953  1.00 43.83  ? 251 VAL E CB  1 
ATOM   11025 C  CG1 . VAL E 1 251 ? 8.586   -25.013 24.989  1.00 45.48  ? 251 VAL E CG1 1 
ATOM   11026 C  CG2 . VAL E 1 251 ? 10.392  -26.744 24.669  1.00 42.50  ? 251 VAL E CG2 1 
ATOM   11027 N  N   . GLY E 1 252 ? 9.298   -29.374 26.529  1.00 34.48  ? 252 GLY E N   1 
ATOM   11028 C  CA  . GLY E 1 252 ? 9.323   -30.828 26.479  1.00 36.05  ? 252 GLY E CA  1 
ATOM   11029 C  C   . GLY E 1 252 ? 8.289   -31.456 27.414  1.00 38.58  ? 252 GLY E C   1 
ATOM   11030 O  O   . GLY E 1 252 ? 7.668   -32.442 27.060  1.00 39.22  ? 252 GLY E O   1 
ATOM   11031 N  N   . ARG E 1 253 ? 8.043   -30.852 28.573  1.00 41.87  ? 253 ARG E N   1 
ATOM   11032 C  CA  . ARG E 1 253 ? 7.089   -31.390 29.526  1.00 42.06  ? 253 ARG E CA  1 
ATOM   11033 C  C   . ARG E 1 253 ? 5.735   -30.702 29.417  1.00 39.23  ? 253 ARG E C   1 
ATOM   11034 O  O   . ARG E 1 253 ? 4.875   -30.956 30.232  1.00 49.29  ? 253 ARG E O   1 
ATOM   11035 C  CB  . ARG E 1 253 ? 7.651   -31.210 30.934  1.00 49.83  ? 253 ARG E CB  1 
ATOM   11036 C  CG  . ARG E 1 253 ? 8.954   -31.986 31.086  1.00 64.71  ? 253 ARG E CG  1 
ATOM   11037 C  CD  . ARG E 1 253 ? 9.093   -32.493 32.508  1.00 77.74  ? 253 ARG E CD  1 
ATOM   11038 N  NE  . ARG E 1 253 ? 8.719   -31.383 33.391  1.00 95.24  ? 253 ARG E NE  1 
ATOM   11039 C  CZ  . ARG E 1 253 ? 9.417   -30.265 33.516  1.00 98.28  ? 253 ARG E CZ  1 
ATOM   11040 N  NH1 . ARG E 1 253 ? 10.671  -30.179 33.101  1.00 92.08  ? 253 ARG E NH1 1 
ATOM   11041 N  NH2 . ARG E 1 253 ? 8.846   -29.230 34.099  1.00 103.35 ? 253 ARG E NH2 1 
ATOM   11042 N  N   . GLU E 1 254 ? 5.538   -29.863 28.402  1.00 39.66  ? 254 GLU E N   1 
ATOM   11043 C  CA  . GLU E 1 254 ? 4.304   -29.113 28.223  1.00 40.75  ? 254 GLU E CA  1 
ATOM   11044 C  C   . GLU E 1 254 ? 3.918   -28.351 29.487  1.00 36.07  ? 254 GLU E C   1 
ATOM   11045 O  O   . GLU E 1 254 ? 2.760   -28.311 29.816  1.00 38.99  ? 254 GLU E O   1 
ATOM   11046 C  CB  . GLU E 1 254 ? 3.166   -30.016 27.747  1.00 43.06  ? 254 GLU E CB  1 
ATOM   11047 C  CG  . GLU E 1 254 ? 3.472   -30.598 26.377  1.00 57.75  ? 254 GLU E CG  1 
ATOM   11048 C  CD  . GLU E 1 254 ? 2.358   -31.271 25.621  1.00 71.49  ? 254 GLU E CD  1 
ATOM   11049 O  OE1 . GLU E 1 254 ? 1.826   -32.177 26.288  1.00 76.37  ? 254 GLU E OE1 1 
ATOM   11050 O  OE2 . GLU E 1 254 ? 2.082   -30.932 24.430  1.00 87.70  ? 254 GLU E OE2 1 
ATOM   11051 N  N   . GLU E 1 255 ? 4.865   -27.707 30.170  1.00 37.11  ? 255 GLU E N   1 
ATOM   11052 C  CA  . GLU E 1 255 ? 4.556   -26.845 31.303  1.00 37.23  ? 255 GLU E CA  1 
ATOM   11053 C  C   . GLU E 1 255 ? 4.656   -25.386 30.889  1.00 32.68  ? 255 GLU E C   1 
ATOM   11054 O  O   . GLU E 1 255 ? 5.723   -24.934 30.503  1.00 36.94  ? 255 GLU E O   1 
ATOM   11055 C  CB  . GLU E 1 255 ? 5.527   -27.055 32.458  1.00 44.97  ? 255 GLU E CB  1 
ATOM   11056 C  CG  . GLU E 1 255 ? 5.277   -28.367 33.185  1.00 61.07  ? 255 GLU E CG  1 
ATOM   11057 C  CD  . GLU E 1 255 ? 6.003   -28.403 34.507  1.00 67.51  ? 255 GLU E CD  1 
ATOM   11058 O  OE1 . GLU E 1 255 ? 5.876   -29.434 35.192  1.00 65.10  ? 255 GLU E OE1 1 
ATOM   11059 O  OE2 . GLU E 1 255 ? 6.778   -27.450 34.801  1.00 64.90  ? 255 GLU E OE2 1 
ATOM   11060 N  N   . PHE E 1 256 ? 3.559   -24.649 31.009  1.00 28.98  ? 256 PHE E N   1 
ATOM   11061 C  CA  . PHE E 1 256 ? 3.575   -23.208 30.806  1.00 26.86  ? 256 PHE E CA  1 
ATOM   11062 C  C   . PHE E 1 256 ? 2.970   -22.559 32.046  1.00 24.73  ? 256 PHE E C   1 
ATOM   11063 O  O   . PHE E 1 256 ? 1.886   -22.898 32.438  1.00 28.50  ? 256 PHE E O   1 
ATOM   11064 C  CB  . PHE E 1 256 ? 2.817   -22.837 29.530  1.00 29.44  ? 256 PHE E CB  1 
ATOM   11065 C  CG  . PHE E 1 256 ? 3.326   -23.612 28.334  1.00 33.55  ? 256 PHE E CG  1 
ATOM   11066 C  CD1 . PHE E 1 256 ? 2.975   -24.941 28.152  1.00 32.78  ? 256 PHE E CD1 1 
ATOM   11067 C  CD2 . PHE E 1 256 ? 4.163   -23.014 27.405  1.00 41.74  ? 256 PHE E CD2 1 
ATOM   11068 C  CE1 . PHE E 1 256 ? 3.479   -25.671 27.091  1.00 35.82  ? 256 PHE E CE1 1 
ATOM   11069 C  CE2 . PHE E 1 256 ? 4.667   -23.753 26.342  1.00 42.26  ? 256 PHE E CE2 1 
ATOM   11070 C  CZ  . PHE E 1 256 ? 4.337   -25.085 26.200  1.00 38.33  ? 256 PHE E CZ  1 
ATOM   11071 N  N   . GLY E 1 257 ? 3.662   -21.643 32.696  1.00 23.29  ? 257 GLY E N   1 
ATOM   11072 C  CA  . GLY E 1 257 ? 3.269   -21.252 34.027  1.00 24.19  ? 257 GLY E CA  1 
ATOM   11073 C  C   . GLY E 1 257 ? 3.408   -19.752 34.257  1.00 24.92  ? 257 GLY E C   1 
ATOM   11074 O  O   . GLY E 1 257 ? 4.043   -19.060 33.481  1.00 24.43  ? 257 GLY E O   1 
ATOM   11075 N  N   . THR E 1 258 ? 2.714   -19.263 35.290  1.00 23.83  ? 258 THR E N   1 
ATOM   11076 C  CA  . THR E 1 258 ? 2.908   -17.926 35.786  1.00 24.54  ? 258 THR E CA  1 
ATOM   11077 C  C   . THR E 1 258 ? 3.281   -18.075 37.251  1.00 28.01  ? 258 THR E C   1 
ATOM   11078 O  O   . THR E 1 258 ? 2.579   -18.750 37.974  1.00 29.63  ? 258 THR E O   1 
ATOM   11079 C  CB  . THR E 1 258 ? 1.680   -17.056 35.577  1.00 23.05  ? 258 THR E CB  1 
ATOM   11080 O  OG1 . THR E 1 258 ? 1.583   -16.753 34.178  1.00 26.45  ? 258 THR E OG1 1 
ATOM   11081 C  CG2 . THR E 1 258 ? 1.876   -15.748 36.342  1.00 25.38  ? 258 THR E CG2 1 
ATOM   11082 N  N   . TYR E 1 259 ? 4.411   -17.489 37.670  1.00 26.02  ? 259 TYR E N   1 
ATOM   11083 C  CA  . TYR E 1 259 ? 4.779   -17.500 39.072  1.00 23.83  ? 259 TYR E CA  1 
ATOM   11084 C  C   . TYR E 1 259 ? 4.291   -16.180 39.645  1.00 23.15  ? 259 TYR E C   1 
ATOM   11085 O  O   . TYR E 1 259 ? 4.759   -15.127 39.280  1.00 22.52  ? 259 TYR E O   1 
ATOM   11086 C  CB  . TYR E 1 259 ? 6.270   -17.757 39.302  1.00 25.08  ? 259 TYR E CB  1 
ATOM   11087 C  CG  . TYR E 1 259 ? 6.631   -18.214 40.709  1.00 24.07  ? 259 TYR E CG  1 
ATOM   11088 C  CD1 . TYR E 1 259 ? 6.795   -17.299 41.721  1.00 24.99  ? 259 TYR E CD1 1 
ATOM   11089 C  CD2 . TYR E 1 259 ? 6.851   -19.543 40.995  1.00 21.54  ? 259 TYR E CD2 1 
ATOM   11090 C  CE1 . TYR E 1 259 ? 7.102   -17.694 43.009  1.00 26.01  ? 259 TYR E CE1 1 
ATOM   11091 C  CE2 . TYR E 1 259 ? 7.163   -19.968 42.269  1.00 25.23  ? 259 TYR E CE2 1 
ATOM   11092 C  CZ  . TYR E 1 259 ? 7.293   -19.036 43.283  1.00 28.47  ? 259 TYR E CZ  1 
ATOM   11093 O  OH  . TYR E 1 259 ? 7.617   -19.434 44.552  1.00 29.64  ? 259 TYR E OH  1 
ATOM   11094 N  N   . PHE E 1 260 ? 3.271   -16.245 40.495  1.00 23.84  ? 260 PHE E N   1 
ATOM   11095 C  CA  . PHE E 1 260 ? 2.723   -15.064 41.114  1.00 22.26  ? 260 PHE E CA  1 
ATOM   11096 C  C   . PHE E 1 260 ? 3.492   -14.742 42.380  1.00 22.51  ? 260 PHE E C   1 
ATOM   11097 O  O   . PHE E 1 260 ? 3.686   -15.597 43.250  1.00 21.47  ? 260 PHE E O   1 
ATOM   11098 C  CB  . PHE E 1 260 ? 1.276   -15.360 41.485  1.00 23.51  ? 260 PHE E CB  1 
ATOM   11099 C  CG  . PHE E 1 260 ? 0.712   -14.273 42.378  1.00 23.89  ? 260 PHE E CG  1 
ATOM   11100 C  CD1 . PHE E 1 260 ? 0.297   -13.062 41.847  1.00 24.76  ? 260 PHE E CD1 1 
ATOM   11101 C  CD2 . PHE E 1 260 ? 0.653   -14.443 43.754  1.00 24.20  ? 260 PHE E CD2 1 
ATOM   11102 C  CE1 . PHE E 1 260 ? -0.166  -12.041 42.669  1.00 25.75  ? 260 PHE E CE1 1 
ATOM   11103 C  CE2 . PHE E 1 260 ? 0.159   -13.432 44.553  1.00 24.66  ? 260 PHE E CE2 1 
ATOM   11104 C  CZ  . PHE E 1 260 ? -0.277  -12.250 44.007  1.00 24.33  ? 260 PHE E CZ  1 
ATOM   11105 N  N   . ILE E 1 261 ? 3.874   -13.476 42.510  1.00 23.56  ? 261 ILE E N   1 
ATOM   11106 C  CA  . ILE E 1 261 ? 4.355   -12.971 43.789  1.00 25.96  ? 261 ILE E CA  1 
ATOM   11107 C  C   . ILE E 1 261 ? 3.728   -11.599 44.015  1.00 25.05  ? 261 ILE E C   1 
ATOM   11108 O  O   . ILE E 1 261 ? 3.734   -10.743 43.139  1.00 28.43  ? 261 ILE E O   1 
ATOM   11109 C  CB  . ILE E 1 261 ? 5.899   -12.950 43.868  1.00 25.68  ? 261 ILE E CB  1 
ATOM   11110 C  CG1 . ILE E 1 261 ? 6.364   -12.551 45.270  1.00 27.00  ? 261 ILE E CG1 1 
ATOM   11111 C  CG2 . ILE E 1 261 ? 6.534   -12.042 42.807  1.00 26.66  ? 261 ILE E CG2 1 
ATOM   11112 C  CD1 . ILE E 1 261 ? 7.839   -12.811 45.508  1.00 27.04  ? 261 ILE E CD1 1 
ATOM   11113 N  N   . GLY E 1 262 ? 3.099   -11.432 45.171  1.00 25.40  ? 262 GLY E N   1 
ATOM   11114 C  CA  . GLY E 1 262 ? 2.457   -10.173 45.537  1.00 27.49  ? 262 GLY E CA  1 
ATOM   11115 C  C   . GLY E 1 262 ? 2.930   -9.680  46.910  1.00 27.81  ? 262 GLY E C   1 
ATOM   11116 O  O   . GLY E 1 262 ? 2.939   -10.430 47.899  1.00 28.98  ? 262 GLY E O   1 
ATOM   11117 N  N   . TYR E 1 263 ? 3.352   -8.418  46.936  1.00 27.07  ? 263 TYR E N   1 
ATOM   11118 C  CA  . TYR E 1 263 ? 3.812   -7.779  48.158  1.00 28.03  ? 263 TYR E CA  1 
ATOM   11119 C  C   . TYR E 1 263 ? 2.778   -6.762  48.629  1.00 29.38  ? 263 TYR E C   1 
ATOM   11120 O  O   . TYR E 1 263 ? 2.212   -6.023  47.823  1.00 29.83  ? 263 TYR E O   1 
ATOM   11121 C  CB  . TYR E 1 263 ? 5.125   -7.028  47.908  1.00 28.69  ? 263 TYR E CB  1 
ATOM   11122 C  CG  . TYR E 1 263 ? 6.361   -7.872  47.649  1.00 26.96  ? 263 TYR E CG  1 
ATOM   11123 C  CD1 . TYR E 1 263 ? 7.167   -8.275  48.685  1.00 26.89  ? 263 TYR E CD1 1 
ATOM   11124 C  CD2 . TYR E 1 263 ? 6.748   -8.230  46.370  1.00 28.54  ? 263 TYR E CD2 1 
ATOM   11125 C  CE1 . TYR E 1 263 ? 8.310   -9.019  48.470  1.00 27.25  ? 263 TYR E CE1 1 
ATOM   11126 C  CE2 . TYR E 1 263 ? 7.888   -8.981  46.130  1.00 27.03  ? 263 TYR E CE2 1 
ATOM   11127 C  CZ  . TYR E 1 263 ? 8.673   -9.383  47.189  1.00 30.12  ? 263 TYR E CZ  1 
ATOM   11128 O  OH  . TYR E 1 263 ? 9.819   -10.118 46.982  1.00 31.94  ? 263 TYR E OH  1 
ATOM   11129 N  N   . ALA E 1 264 ? 2.577   -6.698  49.949  1.00 31.09  ? 264 ALA E N   1 
ATOM   11130 C  CA  . ALA E 1 264 ? 1.666   -5.749  50.576  1.00 30.17  ? 264 ALA E CA  1 
ATOM   11131 C  C   . ALA E 1 264 ? 2.107   -5.463  52.007  1.00 30.80  ? 264 ALA E C   1 
ATOM   11132 O  O   . ALA E 1 264 ? 2.752   -6.331  52.616  1.00 29.91  ? 264 ALA E O   1 
ATOM   11133 C  CB  . ALA E 1 264 ? 0.312   -6.400  50.564  1.00 34.14  ? 264 ALA E CB  1 
ATOM   11134 N  N   . ARG E 1 265 ? 1.702   -4.302  52.560  1.00 34.36  ? 265 ARG E N   1 
ATOM   11135 C  CA  . ARG E 1 265 ? 2.071   -3.903  53.921  1.00 37.00  ? 265 ARG E CA  1 
ATOM   11136 C  C   . ARG E 1 265 ? 1.381   -4.779  54.984  1.00 34.66  ? 265 ARG E C   1 
ATOM   11137 O  O   . ARG E 1 265 ? 1.829   -4.837  56.126  1.00 33.02  ? 265 ARG E O   1 
ATOM   11138 C  CB  . ARG E 1 265 ? 1.812   -2.413  54.192  1.00 39.98  ? 265 ARG E CB  1 
ATOM   11139 C  CG  . ARG E 1 265 ? 0.328   -2.086  54.372  1.00 48.56  ? 265 ARG E CG  1 
ATOM   11140 C  CD  . ARG E 1 265 ? -0.006  -0.593  54.547  1.00 55.13  ? 265 ARG E CD  1 
ATOM   11141 N  NE  . ARG E 1 265 ? 0.731   -0.093  55.720  1.00 60.82  ? 265 ARG E NE  1 
ATOM   11142 C  CZ  . ARG E 1 265 ? 1.397   1.053   55.880  1.00 56.11  ? 265 ARG E CZ  1 
ATOM   11143 N  NH1 . ARG E 1 265 ? 1.891   1.372   57.069  1.00 51.31  ? 265 ARG E NH1 1 
ATOM   11144 N  NH2 . ARG E 1 265 ? 1.569   1.888   54.883  1.00 59.34  ? 265 ARG E NH2 1 
ATOM   11145 N  N   . THR E 1 266 ? 0.285   -5.448  54.611  1.00 35.32  ? 266 THR E N   1 
ATOM   11146 C  CA  . THR E 1 266 ? -0.399  -6.411  55.460  1.00 34.68  ? 266 THR E CA  1 
ATOM   11147 C  C   . THR E 1 266 ? -0.920  -7.536  54.572  1.00 33.36  ? 266 THR E C   1 
ATOM   11148 O  O   . THR E 1 266 ? -1.432  -7.297  53.482  1.00 31.68  ? 266 THR E O   1 
ATOM   11149 C  CB  . THR E 1 266 ? -1.559  -5.769  56.238  1.00 37.66  ? 266 THR E CB  1 
ATOM   11150 O  OG1 . THR E 1 266 ? -2.379  -6.819  56.758  1.00 41.57  ? 266 THR E OG1 1 
ATOM   11151 C  CG2 . THR E 1 266 ? -2.481  -4.922  55.373  1.00 36.04  ? 266 THR E CG2 1 
ATOM   11152 N  N   . PRO E 1 267 ? -0.872  -8.807  55.017  1.00 32.78  ? 267 PRO E N   1 
ATOM   11153 C  CA  . PRO E 1 267 ? -1.425  -9.884  54.209  1.00 35.35  ? 267 PRO E CA  1 
ATOM   11154 C  C   . PRO E 1 267 ? -2.935  -9.816  54.032  1.00 36.92  ? 267 PRO E C   1 
ATOM   11155 O  O   . PRO E 1 267 ? -3.433  -10.476 53.121  1.00 36.67  ? 267 PRO E O   1 
ATOM   11156 C  CB  . PRO E 1 267 ? -0.970  -11.154 54.913  1.00 35.70  ? 267 PRO E CB  1 
ATOM   11157 C  CG  . PRO E 1 267 ? -0.700  -10.727 56.326  1.00 33.92  ? 267 PRO E CG  1 
ATOM   11158 C  CD  . PRO E 1 267 ? -0.318  -9.274  56.287  1.00 32.75  ? 267 PRO E CD  1 
ATOM   11159 N  N   . GLU E 1 268 ? -3.646  -9.008  54.856  1.00 36.10  ? 268 GLU E N   1 
ATOM   11160 C  CA  . GLU E 1 268 ? -5.102  -8.954  54.789  1.00 34.93  ? 268 GLU E CA  1 
ATOM   11161 C  C   . GLU E 1 268 ? -5.479  -8.529  53.351  1.00 37.26  ? 268 GLU E C   1 
ATOM   11162 O  O   . GLU E 1 268 ? -6.434  -9.050  52.756  1.00 40.20  ? 268 GLU E O   1 
ATOM   11163 C  CB  . GLU E 1 268 ? -5.722  -8.108  55.923  1.00 38.04  ? 268 GLU E CB  1 
ATOM   11164 C  CG  . GLU E 1 268 ? -5.556  -8.607  57.371  1.00 37.94  ? 268 GLU E CG  1 
ATOM   11165 N  N   . VAL E 1 269 ? -4.687  -7.644  52.722  1.00 31.36  ? 269 VAL E N   1 
ATOM   11166 C  CA  . VAL E 1 269 ? -5.064  -7.164  51.405  1.00 31.91  ? 269 VAL E CA  1 
ATOM   11167 C  C   . VAL E 1 269 ? -4.985  -8.300  50.375  1.00 32.29  ? 269 VAL E C   1 
ATOM   11168 O  O   . VAL E 1 269 ? -5.942  -8.565  49.618  1.00 31.14  ? 269 VAL E O   1 
ATOM   11169 C  CB  . VAL E 1 269 ? -4.211  -5.947  51.004  1.00 32.34  ? 269 VAL E CB  1 
ATOM   11170 C  CG1 . VAL E 1 269 ? -4.547  -5.442  49.615  1.00 32.43  ? 269 VAL E CG1 1 
ATOM   11171 C  CG2 . VAL E 1 269 ? -4.394  -4.799  51.968  1.00 30.43  ? 269 VAL E CG2 1 
ATOM   11172 N  N   . THR E 1 270 ? -3.809  -8.937  50.341  1.00 28.94  ? 270 THR E N   1 
ATOM   11173 C  CA  . THR E 1 270 ? -3.556  -10.024 49.414  1.00 30.21  ? 270 THR E CA  1 
ATOM   11174 C  C   . THR E 1 270 ? -4.571  -11.150 49.646  1.00 31.96  ? 270 THR E C   1 
ATOM   11175 O  O   . THR E 1 270 ? -5.072  -11.745 48.673  1.00 31.92  ? 270 THR E O   1 
ATOM   11176 C  CB  . THR E 1 270 ? -2.116  -10.523 49.562  1.00 29.65  ? 270 THR E CB  1 
ATOM   11177 O  OG1 . THR E 1 270 ? -1.148  -9.479  49.481  1.00 34.72  ? 270 THR E OG1 1 
ATOM   11178 C  CG2 . THR E 1 270 ? -1.764  -11.504 48.464  1.00 31.18  ? 270 THR E CG2 1 
ATOM   11179 N  N   . GLU E 1 271 ? -4.880  -11.453 50.929  1.00 34.04  ? 271 GLU E N   1 
ATOM   11180 C  CA  . GLU E 1 271 ? -5.751  -12.579 51.277  1.00 30.83  ? 271 GLU E CA  1 
ATOM   11181 C  C   . GLU E 1 271 ? -7.184  -12.280 50.846  1.00 29.37  ? 271 GLU E C   1 
ATOM   11182 O  O   . GLU E 1 271 ? -7.911  -13.185 50.459  1.00 29.52  ? 271 GLU E O   1 
ATOM   11183 C  CB  . GLU E 1 271 ? -5.707  -12.905 52.766  1.00 31.39  ? 271 GLU E CB  1 
ATOM   11184 C  CG  . GLU E 1 271 ? -4.468  -13.688 53.159  1.00 33.72  ? 271 GLU E CG  1 
ATOM   11185 C  CD  . GLU E 1 271 ? -4.128  -13.761 54.633  1.00 35.36  ? 271 GLU E CD  1 
ATOM   11186 O  OE1 . GLU E 1 271 ? -4.756  -13.060 55.460  1.00 37.04  ? 271 GLU E OE1 1 
ATOM   11187 O  OE2 . GLU E 1 271 ? -3.179  -14.533 54.913  1.00 39.63  ? 271 GLU E OE2 1 
ATOM   11188 N  N   . THR E 1 272 ? -7.594  -11.011 50.893  1.00 27.90  ? 272 THR E N   1 
ATOM   11189 C  CA  . THR E 1 272 ? -8.931  -10.667 50.446  1.00 29.10  ? 272 THR E CA  1 
ATOM   11190 C  C   . THR E 1 272 ? -9.065  -10.949 48.947  1.00 34.38  ? 272 THR E C   1 
ATOM   11191 O  O   . THR E 1 272 ? -10.070 -11.496 48.486  1.00 39.67  ? 272 THR E O   1 
ATOM   11192 C  CB  . THR E 1 272 ? -9.187  -9.192  50.686  1.00 30.14  ? 272 THR E CB  1 
ATOM   11193 O  OG1 . THR E 1 272 ? -9.169  -9.032  52.081  1.00 33.32  ? 272 THR E OG1 1 
ATOM   11194 C  CG2 . THR E 1 272 ? -10.553 -8.741  50.218  1.00 33.85  ? 272 THR E CG2 1 
ATOM   11195 N  N   . MET E 1 273 ? -8.065  -10.515 48.174  1.00 30.31  ? 273 MET E N   1 
ATOM   11196 C  CA  . MET E 1 273 ? -8.117  -10.690 46.741  1.00 28.20  ? 273 MET E CA  1 
ATOM   11197 C  C   . MET E 1 273 ? -8.212  -12.175 46.430  1.00 26.05  ? 273 MET E C   1 
ATOM   11198 O  O   . MET E 1 273 ? -8.958  -12.603 45.541  1.00 23.47  ? 273 MET E O   1 
ATOM   11199 C  CB  . MET E 1 273 ? -6.876  -10.069 46.096  1.00 32.18  ? 273 MET E CB  1 
ATOM   11200 C  CG  . MET E 1 273 ? -6.888  -8.545  46.122  1.00 37.23  ? 273 MET E CG  1 
ATOM   11201 S  SD  . MET E 1 273 ? -5.316  -7.878  45.542  1.00 35.14  ? 273 MET E SD  1 
ATOM   11202 C  CE  . MET E 1 273 ? -5.496  -6.096  45.721  1.00 31.01  ? 273 MET E CE  1 
ATOM   11203 N  N   . LEU E 1 274 ? -7.469  -12.969 47.204  1.00 25.15  ? 274 LEU E N   1 
ATOM   11204 C  CA  . LEU E 1 274 ? -7.467  -14.406 46.982  1.00 30.07  ? 274 LEU E CA  1 
ATOM   11205 C  C   . LEU E 1 274 ? -8.840  -15.017 47.261  1.00 33.19  ? 274 LEU E C   1 
ATOM   11206 O  O   . LEU E 1 274 ? -9.270  -15.907 46.517  1.00 30.19  ? 274 LEU E O   1 
ATOM   11207 C  CB  . LEU E 1 274 ? -6.396  -15.062 47.845  1.00 32.69  ? 274 LEU E CB  1 
ATOM   11208 C  CG  . LEU E 1 274 ? -4.958  -14.998 47.323  1.00 36.13  ? 274 LEU E CG  1 
ATOM   11209 C  CD1 . LEU E 1 274 ? -3.918  -15.485 48.312  1.00 36.64  ? 274 LEU E CD1 1 
ATOM   11210 C  CD2 . LEU E 1 274 ? -4.857  -15.818 46.069  1.00 40.81  ? 274 LEU E CD2 1 
ATOM   11211 N  N   . GLU E 1 275 ? -9.512  -14.553 48.337  1.00 32.65  ? 275 GLU E N   1 
ATOM   11212 C  CA  . GLU E 1 275 ? -10.835 -15.065 48.681  1.00 36.27  ? 275 GLU E CA  1 
ATOM   11213 C  C   . GLU E 1 275 ? -11.824 -14.736 47.566  1.00 33.46  ? 275 GLU E C   1 
ATOM   11214 O  O   . GLU E 1 275 ? -12.625 -15.572 47.149  1.00 28.42  ? 275 GLU E O   1 
ATOM   11215 C  CB  . GLU E 1 275 ? -11.398 -14.500 49.983  1.00 41.81  ? 275 GLU E CB  1 
ATOM   11216 C  CG  . GLU E 1 275 ? -10.720 -15.045 51.239  1.00 47.08  ? 275 GLU E CG  1 
ATOM   11217 C  CD  . GLU E 1 275 ? -11.084 -14.344 52.538  1.00 47.10  ? 275 GLU E CD  1 
ATOM   11218 O  OE1 . GLU E 1 275 ? -12.101 -13.617 52.581  1.00 44.39  ? 275 GLU E OE1 1 
ATOM   11219 O  OE2 . GLU E 1 275 ? -10.334 -14.550 53.505  1.00 57.52  ? 275 GLU E OE2 1 
ATOM   11220 N  N   . ARG E 1 276 ? -11.754 -13.503 47.068  1.00 30.96  ? 276 ARG E N   1 
ATOM   11221 C  CA  . ARG E 1 276 ? -12.627 -13.113 45.976  1.00 28.91  ? 276 ARG E CA  1 
ATOM   11222 C  C   . ARG E 1 276 ? -12.400 -13.971 44.740  1.00 28.50  ? 276 ARG E C   1 
ATOM   11223 O  O   . ARG E 1 276 ? -13.347 -14.293 44.032  1.00 27.64  ? 276 ARG E O   1 
ATOM   11224 C  CB  . ARG E 1 276 ? -12.450 -11.636 45.684  1.00 29.83  ? 276 ARG E CB  1 
ATOM   11225 C  CG  . ARG E 1 276 ? -13.189 -10.894 46.789  1.00 33.81  ? 276 ARG E CG  1 
ATOM   11226 C  CD  . ARG E 1 276 ? -12.599 -9.531  47.038  1.00 47.13  ? 276 ARG E CD  1 
ATOM   11227 N  NE  . ARG E 1 276 ? -12.747 -8.671  45.861  1.00 57.44  ? 276 ARG E NE  1 
ATOM   11228 C  CZ  . ARG E 1 276 ? -13.861 -8.073  45.545  1.00 57.78  ? 276 ARG E CZ  1 
ATOM   11229 N  NH1 . ARG E 1 276 ? -13.983 -7.551  44.336  1.00 50.83  ? 276 ARG E NH1 1 
ATOM   11230 N  NH2 . ARG E 1 276 ? -14.840 -8.064  46.435  1.00 64.93  ? 276 ARG E NH2 1 
ATOM   11231 N  N   . MET E 1 277 ? -11.140 -14.306 44.444  1.00 29.43  ? 277 MET E N   1 
ATOM   11232 C  CA  . MET E 1 277 ? -10.863 -15.076 43.240  1.00 29.25  ? 277 MET E CA  1 
ATOM   11233 C  C   . MET E 1 277 ? -11.341 -16.516 43.401  1.00 28.00  ? 277 MET E C   1 
ATOM   11234 O  O   . MET E 1 277 ? -11.924 -17.098 42.499  1.00 23.35  ? 277 MET E O   1 
ATOM   11235 C  CB  . MET E 1 277 ? -9.366  -15.086 42.916  1.00 32.59  ? 277 MET E CB  1 
ATOM   11236 C  CG  . MET E 1 277 ? -8.761  -13.723 42.433  1.00 35.11  ? 277 MET E CG  1 
ATOM   11237 S  SD  . MET E 1 277 ? -6.948  -13.738 42.338  1.00 32.05  ? 277 MET E SD  1 
ATOM   11238 C  CE  . MET E 1 277 ? -6.749  -15.089 41.164  1.00 27.71  ? 277 MET E CE  1 
ATOM   11239 N  N   . PHE E 1 278 ? -11.063 -17.110 44.564  1.00 32.77  ? 278 PHE E N   1 
ATOM   11240 C  CA  . PHE E 1 278 ? -11.247 -18.539 44.734  1.00 34.38  ? 278 PHE E CA  1 
ATOM   11241 C  C   . PHE E 1 278 ? -12.643 -18.882 45.249  1.00 34.56  ? 278 PHE E C   1 
ATOM   11242 O  O   . PHE E 1 278 ? -13.144 -19.967 44.929  1.00 29.54  ? 278 PHE E O   1 
ATOM   11243 C  CB  . PHE E 1 278 ? -10.159 -19.023 45.697  1.00 33.30  ? 278 PHE E CB  1 
ATOM   11244 C  CG  . PHE E 1 278 ? -8.911  -19.402 44.916  1.00 37.25  ? 278 PHE E CG  1 
ATOM   11245 C  CD1 . PHE E 1 278 ? -8.756  -20.686 44.362  1.00 35.44  ? 278 PHE E CD1 1 
ATOM   11246 C  CD2 . PHE E 1 278 ? -7.913  -18.453 44.720  1.00 34.21  ? 278 PHE E CD2 1 
ATOM   11247 C  CE1 . PHE E 1 278 ? -7.631  -20.996 43.611  1.00 33.63  ? 278 PHE E CE1 1 
ATOM   11248 C  CE2 . PHE E 1 278 ? -6.778  -18.787 44.014  1.00 31.78  ? 278 PHE E CE2 1 
ATOM   11249 C  CZ  . PHE E 1 278 ? -6.636  -20.042 43.452  1.00 32.69  ? 278 PHE E CZ  1 
ATOM   11250 N  N   . LEU E 1 279 ? -13.203 -17.989 46.079  1.00 35.29  ? 279 LEU E N   1 
ATOM   11251 C  CA  . LEU E 1 279 ? -14.478 -18.256 46.732  1.00 40.44  ? 279 LEU E CA  1 
ATOM   11252 C  C   . LEU E 1 279 ? -15.611 -17.503 46.051  1.00 40.23  ? 279 LEU E C   1 
ATOM   11253 O  O   . LEU E 1 279 ? -16.765 -17.882 46.180  1.00 42.61  ? 279 LEU E O   1 
ATOM   11254 C  CB  . LEU E 1 279 ? -14.433 -17.904 48.220  1.00 34.79  ? 279 LEU E CB  1 
ATOM   11255 C  CG  . LEU E 1 279 ? -13.382 -18.656 49.032  1.00 34.86  ? 279 LEU E CG  1 
ATOM   11256 C  CD1 . LEU E 1 279 ? -13.457 -18.111 50.430  1.00 33.45  ? 279 LEU E CD1 1 
ATOM   11257 C  CD2 . LEU E 1 279 ? -13.483 -20.216 48.944  1.00 33.40  ? 279 LEU E CD2 1 
ATOM   11258 N  N   . GLY E 1 280 ? -15.293 -16.427 45.361  1.00 41.76  ? 280 GLY E N   1 
ATOM   11259 C  CA  . GLY E 1 280 ? -16.320 -15.722 44.612  1.00 45.20  ? 280 GLY E CA  1 
ATOM   11260 C  C   . GLY E 1 280 ? -16.956 -14.638 45.475  1.00 47.65  ? 280 GLY E C   1 
ATOM   11261 O  O   . GLY E 1 280 ? -16.580 -14.489 46.644  1.00 40.06  ? 280 GLY E O   1 
ATOM   11262 N  N   . THR E 1 281 ? -17.888 -13.894 44.850  1.00 45.57  ? 281 THR E N   1 
ATOM   11263 C  CA  . THR E 1 281 ? -18.651 -12.843 45.500  1.00 51.59  ? 281 THR E CA  1 
ATOM   11264 C  C   . THR E 1 281 ? -20.134 -13.108 45.301  1.00 63.09  ? 281 THR E C   1 
ATOM   11265 O  O   . THR E 1 281 ? -20.493 -14.152 44.761  1.00 60.66  ? 281 THR E O   1 
ATOM   11266 C  CB  . THR E 1 281 ? -18.260 -11.474 44.951  1.00 49.62  ? 281 THR E CB  1 
ATOM   11267 O  OG1 . THR E 1 281 ? -18.676 -11.402 43.586  1.00 41.00  ? 281 THR E OG1 1 
ATOM   11268 C  CG2 . THR E 1 281 ? -16.787 -11.230 45.190  1.00 51.03  ? 281 THR E CG2 1 
ATOM   11269 N  N   . ALA E 1 282 ? -20.966 -12.149 45.744  1.00 77.64  ? 282 ALA E N   1 
ATOM   11270 C  CA  . ALA E 1 282 ? -22.385 -12.160 45.432  1.00 70.35  ? 282 ALA E CA  1 
ATOM   11271 C  C   . ALA E 1 282 ? -22.581 -12.349 43.924  1.00 72.98  ? 282 ALA E C   1 
ATOM   11272 O  O   . ALA E 1 282 ? -23.324 -13.241 43.498  1.00 56.51  ? 282 ALA E O   1 
ATOM   11273 C  CB  . ALA E 1 282 ? -23.020 -10.888 45.934  1.00 61.84  ? 282 ALA E CB  1 
ATOM   11274 N  N   . SER E 1 283 ? -21.862 -11.545 43.125  1.00 75.71  ? 283 SER E N   1 
ATOM   11275 C  CA  . SER E 1 283 ? -22.133 -11.477 41.697  1.00 68.73  ? 283 SER E CA  1 
ATOM   11276 C  C   . SER E 1 283 ? -21.209 -12.357 40.847  1.00 63.28  ? 283 SER E C   1 
ATOM   11277 O  O   . SER E 1 283 ? -21.372 -12.351 39.635  1.00 67.01  ? 283 SER E O   1 
ATOM   11278 C  CB  . SER E 1 283 ? -22.142 -10.043 41.217  1.00 64.02  ? 283 SER E CB  1 
ATOM   11279 O  OG  . SER E 1 283 ? -21.094 -9.338  41.847  1.00 62.43  ? 283 SER E OG  1 
ATOM   11280 N  N   . ALA E 1 284 ? -20.270 -13.124 41.423  1.00 54.41  ? 284 ALA E N   1 
ATOM   11281 C  CA  . ALA E 1 284 ? -19.318 -13.858 40.599  1.00 46.67  ? 284 ALA E CA  1 
ATOM   11282 C  C   . ALA E 1 284 ? -18.950 -15.193 41.235  1.00 41.21  ? 284 ALA E C   1 
ATOM   11283 O  O   . ALA E 1 284 ? -18.431 -15.243 42.348  1.00 37.53  ? 284 ALA E O   1 
ATOM   11284 C  CB  . ALA E 1 284 ? -18.074 -13.027 40.381  1.00 43.73  ? 284 ALA E CB  1 
ATOM   11285 N  N   . PRO E 1 285 ? -19.139 -16.328 40.543  1.00 38.01  ? 285 PRO E N   1 
ATOM   11286 C  CA  . PRO E 1 285 ? -18.768 -17.622 41.120  1.00 41.78  ? 285 PRO E CA  1 
ATOM   11287 C  C   . PRO E 1 285 ? -17.291 -17.727 41.519  1.00 43.27  ? 285 PRO E C   1 
ATOM   11288 O  O   . PRO E 1 285 ? -16.972 -18.326 42.537  1.00 45.62  ? 285 PRO E O   1 
ATOM   11289 C  CB  . PRO E 1 285 ? -19.161 -18.642 40.017  1.00 37.58  ? 285 PRO E CB  1 
ATOM   11290 C  CG  . PRO E 1 285 ? -19.212 -17.821 38.723  1.00 39.77  ? 285 PRO E CG  1 
ATOM   11291 C  CD  . PRO E 1 285 ? -19.674 -16.430 39.182  1.00 37.15  ? 285 PRO E CD  1 
ATOM   11292 N  N   . HIS E 1 286 ? -16.412 -17.184 40.671  1.00 46.60  ? 286 HIS E N   1 
ATOM   11293 C  CA  . HIS E 1 286 ? -14.972 -17.187 40.866  1.00 39.95  ? 286 HIS E CA  1 
ATOM   11294 C  C   . HIS E 1 286 ? -14.331 -16.441 39.699  1.00 41.09  ? 286 HIS E C   1 
ATOM   11295 O  O   . HIS E 1 286 ? -14.986 -16.187 38.688  1.00 40.04  ? 286 HIS E O   1 
ATOM   11296 C  CB  . HIS E 1 286 ? -14.400 -18.603 40.951  1.00 34.31  ? 286 HIS E CB  1 
ATOM   11297 C  CG  . HIS E 1 286 ? -14.673 -19.443 39.766  1.00 35.31  ? 286 HIS E CG  1 
ATOM   11298 N  ND1 . HIS E 1 286 ? -15.653 -20.405 39.756  1.00 37.88  ? 286 HIS E ND1 1 
ATOM   11299 C  CD2 . HIS E 1 286 ? -14.081 -19.492 38.566  1.00 38.97  ? 286 HIS E CD2 1 
ATOM   11300 C  CE1 . HIS E 1 286 ? -15.647 -21.004 38.576  1.00 38.64  ? 286 HIS E CE1 1 
ATOM   11301 N  NE2 . HIS E 1 286 ? -14.689 -20.473 37.837  1.00 36.37  ? 286 HIS E NE2 1 
ATOM   11302 N  N   . ASP E 1 287 ? -13.045 -16.125 39.866  1.00 38.65  ? 287 ASP E N   1 
ATOM   11303 C  CA  . ASP E 1 287 ? -12.247 -15.492 38.838  1.00 32.84  ? 287 ASP E CA  1 
ATOM   11304 C  C   . ASP E 1 287 ? -12.098 -16.448 37.659  1.00 30.43  ? 287 ASP E C   1 
ATOM   11305 O  O   . ASP E 1 287 ? -11.594 -17.570 37.799  1.00 29.43  ? 287 ASP E O   1 
ATOM   11306 C  CB  . ASP E 1 287 ? -10.907 -15.088 39.424  1.00 35.91  ? 287 ASP E CB  1 
ATOM   11307 C  CG  . ASP E 1 287 ? -10.007 -14.207 38.559  1.00 40.95  ? 287 ASP E CG  1 
ATOM   11308 O  OD1 . ASP E 1 287 ? -10.180 -14.193 37.320  1.00 45.39  ? 287 ASP E OD1 1 
ATOM   11309 O  OD2 . ASP E 1 287 ? -9.149  -13.515 39.137  1.00 45.60  ? 287 ASP E OD2 1 
ATOM   11310 N  N   . ARG E 1 288 ? -12.504 -15.975 36.478  1.00 30.72  ? 288 ARG E N   1 
ATOM   11311 C  CA  . ARG E 1 288 ? -12.423 -16.801 35.274  1.00 36.26  ? 288 ARG E CA  1 
ATOM   11312 C  C   . ARG E 1 288 ? -10.992 -17.203 34.918  1.00 32.95  ? 288 ARG E C   1 
ATOM   11313 O  O   . ARG E 1 288 ? -10.802 -18.183 34.223  1.00 29.55  ? 288 ARG E O   1 
ATOM   11314 C  CB  . ARG E 1 288 ? -13.059 -16.058 34.098  1.00 39.11  ? 288 ARG E CB  1 
ATOM   11315 C  CG  . ARG E 1 288 ? -14.566 -15.973 34.234  1.00 43.39  ? 288 ARG E CG  1 
ATOM   11316 C  CD  . ARG E 1 288 ? -15.120 -17.293 33.752  1.00 43.28  ? 288 ARG E CD  1 
ATOM   11317 N  NE  . ARG E 1 288 ? -15.042 -17.360 32.285  1.00 44.83  ? 288 ARG E NE  1 
ATOM   11318 C  CZ  . ARG E 1 288 ? -14.688 -18.399 31.533  1.00 48.22  ? 288 ARG E CZ  1 
ATOM   11319 N  NH1 . ARG E 1 288 ? -14.298 -19.538 32.105  1.00 54.52  ? 288 ARG E NH1 1 
ATOM   11320 N  NH2 . ARG E 1 288 ? -14.724 -18.279 30.206  1.00 41.50  ? 288 ARG E NH2 1 
ATOM   11321 N  N   . ILE E 1 289 ? -9.989  -16.452 35.378  1.00 30.37  ? 289 ILE E N   1 
ATOM   11322 C  CA  . ILE E 1 289 ? -8.628  -16.800 35.045  1.00 32.19  ? 289 ILE E CA  1 
ATOM   11323 C  C   . ILE E 1 289 ? -8.261  -18.159 35.641  1.00 29.74  ? 289 ILE E C   1 
ATOM   11324 O  O   . ILE E 1 289 ? -7.355  -18.811 35.114  1.00 29.87  ? 289 ILE E O   1 
ATOM   11325 C  CB  . ILE E 1 289 ? -7.667  -15.685 35.504  1.00 40.02  ? 289 ILE E CB  1 
ATOM   11326 C  CG1 . ILE E 1 289 ? -6.448  -15.611 34.596  1.00 37.90  ? 289 ILE E CG1 1 
ATOM   11327 C  CG2 . ILE E 1 289 ? -7.267  -15.822 36.977  1.00 35.74  ? 289 ILE E CG2 1 
ATOM   11328 C  CD1 . ILE E 1 289 ? -5.648  -14.337 34.806  1.00 33.77  ? 289 ILE E CD1 1 
ATOM   11329 N  N   . LEU E 1 290 ? -8.946  -18.584 36.722  1.00 27.58  ? 290 LEU E N   1 
ATOM   11330 C  CA  . LEU E 1 290 ? -8.679  -19.867 37.383  1.00 25.93  ? 290 LEU E CA  1 
ATOM   11331 C  C   . LEU E 1 290 ? -9.244  -21.019 36.561  1.00 24.79  ? 290 LEU E C   1 
ATOM   11332 O  O   . LEU E 1 290 ? -8.874  -22.169 36.766  1.00 27.46  ? 290 LEU E O   1 
ATOM   11333 C  CB  . LEU E 1 290 ? -9.227  -19.926 38.813  1.00 28.65  ? 290 LEU E CB  1 
ATOM   11334 C  CG  . LEU E 1 290 ? -8.702  -18.836 39.749  1.00 29.63  ? 290 LEU E CG  1 
ATOM   11335 C  CD1 . LEU E 1 290 ? -9.383  -18.822 41.087  1.00 31.70  ? 290 LEU E CD1 1 
ATOM   11336 C  CD2 . LEU E 1 290 ? -7.236  -19.033 39.945  1.00 31.13  ? 290 LEU E CD2 1 
ATOM   11337 N  N   . ASP E 1 291 ? -10.108 -20.730 35.587  1.00 29.12  ? 291 ASP E N   1 
ATOM   11338 C  CA  . ASP E 1 291 ? -10.516 -21.793 34.679  1.00 32.19  ? 291 ASP E CA  1 
ATOM   11339 C  C   . ASP E 1 291 ? -9.389  -22.137 33.704  1.00 33.76  ? 291 ASP E C   1 
ATOM   11340 O  O   . ASP E 1 291 ? -9.527  -23.075 32.937  1.00 33.01  ? 291 ASP E O   1 
ATOM   11341 C  CB  . ASP E 1 291 ? -11.816 -21.502 33.951  1.00 33.97  ? 291 ASP E CB  1 
ATOM   11342 C  CG  . ASP E 1 291 ? -13.042 -21.359 34.856  1.00 35.74  ? 291 ASP E CG  1 
ATOM   11343 O  OD1 . ASP E 1 291 ? -13.182 -22.128 35.828  1.00 35.39  ? 291 ASP E OD1 1 
ATOM   11344 O  OD2 . ASP E 1 291 ? -13.829 -20.440 34.606  1.00 39.96  ? 291 ASP E OD2 1 
ATOM   11345 N  N   . PHE E 1 292 ? -8.267  -21.405 33.731  1.00 31.31  ? 292 PHE E N   1 
ATOM   11346 C  CA  . PHE E 1 292 ? -7.154  -21.711 32.847  1.00 32.46  ? 292 PHE E CA  1 
ATOM   11347 C  C   . PHE E 1 292 ? -5.848  -21.792 33.608  1.00 28.42  ? 292 PHE E C   1 
ATOM   11348 O  O   . PHE E 1 292 ? -4.799  -21.948 32.989  1.00 29.03  ? 292 PHE E O   1 
ATOM   11349 C  CB  . PHE E 1 292 ? -7.037  -20.613 31.786  1.00 34.08  ? 292 PHE E CB  1 
ATOM   11350 C  CG  . PHE E 1 292 ? -8.332  -20.486 31.002  1.00 37.99  ? 292 PHE E CG  1 
ATOM   11351 C  CD1 . PHE E 1 292 ? -8.576  -21.327 29.910  1.00 35.96  ? 292 PHE E CD1 1 
ATOM   11352 C  CD2 . PHE E 1 292 ? -9.314  -19.577 31.399  1.00 33.18  ? 292 PHE E CD2 1 
ATOM   11353 C  CE1 . PHE E 1 292 ? -9.753  -21.223 29.213  1.00 32.93  ? 292 PHE E CE1 1 
ATOM   11354 C  CE2 . PHE E 1 292 ? -10.488 -19.466 30.695  1.00 32.19  ? 292 PHE E CE2 1 
ATOM   11355 C  CZ  . PHE E 1 292 ? -10.709 -20.295 29.616  1.00 33.49  ? 292 PHE E CZ  1 
ATOM   11356 N  N   . SER E 1 293 ? -5.917  -21.661 34.931  1.00 29.19  ? 293 SER E N   1 
ATOM   11357 C  CA  . SER E 1 293 ? -4.718  -21.576 35.734  1.00 32.02  ? 293 SER E CA  1 
ATOM   11358 C  C   . SER E 1 293 ? -4.930  -22.403 37.002  1.00 30.22  ? 293 SER E C   1 
ATOM   11359 O  O   . SER E 1 293 ? -5.884  -22.104 37.703  1.00 36.77  ? 293 SER E O   1 
ATOM   11360 C  CB  . SER E 1 293 ? -4.418  -20.110 36.054  1.00 33.16  ? 293 SER E CB  1 
ATOM   11361 O  OG  . SER E 1 293 ? -4.676  -19.239 34.966  1.00 28.42  ? 293 SER E OG  1 
ATOM   11362 N  N   . THR E 1 294 ? -4.027  -23.344 37.316  1.00 24.61  ? 294 THR E N   1 
ATOM   11363 C  CA  . THR E 1 294 ? -4.074  -24.118 38.548  1.00 25.48  ? 294 THR E CA  1 
ATOM   11364 C  C   . THR E 1 294 ? -2.908  -23.758 39.466  1.00 26.57  ? 294 THR E C   1 
ATOM   11365 O  O   . THR E 1 294 ? -1.765  -23.861 39.022  1.00 26.53  ? 294 THR E O   1 
ATOM   11366 C  CB  . THR E 1 294 ? -3.993  -25.589 38.159  1.00 26.07  ? 294 THR E CB  1 
ATOM   11367 O  OG1 . THR E 1 294 ? -5.253  -25.821 37.553  1.00 28.26  ? 294 THR E OG1 1 
ATOM   11368 C  CG2 . THR E 1 294 ? -3.864  -26.536 39.323  1.00 25.38  ? 294 THR E CG2 1 
ATOM   11369 N  N   . ALA E 1 295 ? -3.216  -23.414 40.730  1.00 25.36  ? 295 ALA E N   1 
ATOM   11370 C  CA  . ALA E 1 295 ? -2.193  -23.176 41.746  1.00 27.63  ? 295 ALA E CA  1 
ATOM   11371 C  C   . ALA E 1 295 ? -1.670  -24.508 42.292  1.00 29.25  ? 295 ALA E C   1 
ATOM   11372 O  O   . ALA E 1 295 ? -2.451  -25.374 42.671  1.00 34.13  ? 295 ALA E O   1 
ATOM   11373 C  CB  . ALA E 1 295 ? -2.711  -22.321 42.869  1.00 25.87  ? 295 ALA E CB  1 
ATOM   11374 N  N   . VAL E 1 296 ? -0.350  -24.687 42.286  1.00 29.58  ? 296 VAL E N   1 
ATOM   11375 C  CA  . VAL E 1 296 ? 0.270   -25.908 42.785  1.00 25.20  ? 296 VAL E CA  1 
ATOM   11376 C  C   . VAL E 1 296 ? 1.200   -25.604 43.954  1.00 23.63  ? 296 VAL E C   1 
ATOM   11377 O  O   . VAL E 1 296 ? 1.733   -26.539 44.536  1.00 26.07  ? 296 VAL E O   1 
ATOM   11378 C  CB  . VAL E 1 296 ? 1.016   -26.709 41.706  1.00 27.84  ? 296 VAL E CB  1 
ATOM   11379 C  CG1 . VAL E 1 296 ? 0.102   -27.018 40.555  1.00 29.51  ? 296 VAL E CG1 1 
ATOM   11380 C  CG2 . VAL E 1 296 ? 2.235   -25.981 41.169  1.00 29.25  ? 296 VAL E CG2 1 
ATOM   11381 N  N   . THR E 1 297 ? 1.425   -24.326 44.292  1.00 22.84  ? 297 THR E N   1 
ATOM   11382 C  CA  . THR E 1 297 ? 2.092   -23.980 45.534  1.00 22.39  ? 297 THR E CA  1 
ATOM   11383 C  C   . THR E 1 297 ? 1.398   -22.773 46.147  1.00 21.38  ? 297 THR E C   1 
ATOM   11384 O  O   . THR E 1 297 ? 0.541   -22.116 45.554  1.00 23.87  ? 297 THR E O   1 
ATOM   11385 C  CB  . THR E 1 297 ? 3.578   -23.678 45.356  1.00 23.41  ? 297 THR E CB  1 
ATOM   11386 O  OG1 . THR E 1 297 ? 3.734   -22.436 44.674  1.00 26.75  ? 297 THR E OG1 1 
ATOM   11387 C  CG2 . THR E 1 297 ? 4.321   -24.784 44.660  1.00 21.54  ? 297 THR E CG2 1 
ATOM   11388 N  N   . GLY E 1 298 ? 1.735   -22.568 47.411  1.00 20.77  ? 298 GLY E N   1 
ATOM   11389 C  CA  . GLY E 1 298 ? 1.162   -21.459 48.153  1.00 24.72  ? 298 GLY E CA  1 
ATOM   11390 C  C   . GLY E 1 298 ? 1.892   -21.258 49.476  1.00 26.56  ? 298 GLY E C   1 
ATOM   11391 O  O   . GLY E 1 298 ? 1.947   -22.175 50.289  1.00 24.46  ? 298 GLY E O   1 
ATOM   11392 N  N   . SER E 1 299 ? 2.490   -20.069 49.657  1.00 24.70  ? 299 SER E N   1 
ATOM   11393 C  CA  . SER E 1 299 ? 3.281   -19.774 50.831  1.00 21.56  ? 299 SER E CA  1 
ATOM   11394 C  C   . SER E 1 299 ? 3.238   -18.277 51.089  1.00 22.40  ? 299 SER E C   1 
ATOM   11395 O  O   . SER E 1 299 ? 3.044   -17.467 50.174  1.00 24.48  ? 299 SER E O   1 
ATOM   11396 C  CB  . SER E 1 299 ? 4.689   -20.215 50.659  1.00 23.15  ? 299 SER E CB  1 
ATOM   11397 O  OG  . SER E 1 299 ? 4.736   -21.565 50.221  1.00 25.75  ? 299 SER E OG  1 
ATOM   11398 N  N   . LEU E 1 300 ? 3.484   -17.945 52.340  1.00 21.65  ? 300 LEU E N   1 
ATOM   11399 C  CA  . LEU E 1 300 ? 3.428   -16.584 52.837  1.00 24.60  ? 300 LEU E CA  1 
ATOM   11400 C  C   . LEU E 1 300 ? 4.713   -16.345 53.624  1.00 22.91  ? 300 LEU E C   1 
ATOM   11401 O  O   . LEU E 1 300 ? 5.122   -17.183 54.434  1.00 21.34  ? 300 LEU E O   1 
ATOM   11402 C  CB  . LEU E 1 300 ? 2.182   -16.372 53.714  1.00 24.96  ? 300 LEU E CB  1 
ATOM   11403 C  CG  . LEU E 1 300 ? 1.863   -14.925 54.096  1.00 27.24  ? 300 LEU E CG  1 
ATOM   11404 C  CD1 . LEU E 1 300 ? 0.420   -14.773 54.533  1.00 31.36  ? 300 LEU E CD1 1 
ATOM   11405 C  CD2 . LEU E 1 300 ? 2.749   -14.461 55.186  1.00 28.28  ? 300 LEU E CD2 1 
ATOM   11406 N  N   . PHE E 1 301 ? 5.327   -15.179 53.392  1.00 23.63  ? 301 PHE E N   1 
ATOM   11407 C  CA  . PHE E 1 301 ? 6.560   -14.820 54.053  1.00 21.71  ? 301 PHE E CA  1 
ATOM   11408 C  C   . PHE E 1 301 ? 6.520   -13.361 54.472  1.00 22.29  ? 301 PHE E C   1 
ATOM   11409 O  O   . PHE E 1 301 ? 5.788   -12.531 53.915  1.00 23.73  ? 301 PHE E O   1 
ATOM   11410 C  CB  . PHE E 1 301 ? 7.739   -14.969 53.094  1.00 22.60  ? 301 PHE E CB  1 
ATOM   11411 C  CG  . PHE E 1 301 ? 7.843   -16.338 52.454  1.00 20.85  ? 301 PHE E CG  1 
ATOM   11412 C  CD1 . PHE E 1 301 ? 8.562   -17.345 53.082  1.00 21.22  ? 301 PHE E CD1 1 
ATOM   11413 C  CD2 . PHE E 1 301 ? 7.227   -16.598 51.247  1.00 19.31  ? 301 PHE E CD2 1 
ATOM   11414 C  CE1 . PHE E 1 301 ? 8.673   -18.595 52.494  1.00 22.18  ? 301 PHE E CE1 1 
ATOM   11415 C  CE2 . PHE E 1 301 ? 7.343   -17.844 50.667  1.00 20.57  ? 301 PHE E CE2 1 
ATOM   11416 C  CZ  . PHE E 1 301 ? 8.061   -18.843 51.293  1.00 21.55  ? 301 PHE E CZ  1 
ATOM   11417 N  N   . PHE E 1 302 ? 7.349   -13.075 55.474  1.00 22.82  ? 302 PHE E N   1 
ATOM   11418 C  CA  . PHE E 1 302 ? 7.628   -11.717 55.874  1.00 21.83  ? 302 PHE E CA  1 
ATOM   11419 C  C   . PHE E 1 302 ? 9.034   -11.384 55.372  1.00 24.33  ? 302 PHE E C   1 
ATOM   11420 O  O   . PHE E 1 302 ? 9.994   -12.140 55.604  1.00 24.10  ? 302 PHE E O   1 
ATOM   11421 C  CB  . PHE E 1 302 ? 7.495   -11.611 57.393  1.00 20.74  ? 302 PHE E CB  1 
ATOM   11422 C  CG  . PHE E 1 302 ? 7.758   -10.195 57.842  1.00 21.49  ? 302 PHE E CG  1 
ATOM   11423 C  CD1 . PHE E 1 302 ? 6.819   -9.198  57.635  1.00 24.33  ? 302 PHE E CD1 1 
ATOM   11424 C  CD2 . PHE E 1 302 ? 8.952   -9.834  58.416  1.00 23.97  ? 302 PHE E CD2 1 
ATOM   11425 C  CE1 . PHE E 1 302 ? 7.068   -7.880  58.029  1.00 24.05  ? 302 PHE E CE1 1 
ATOM   11426 C  CE2 . PHE E 1 302 ? 9.177   -8.513  58.793  1.00 24.05  ? 302 PHE E CE2 1 
ATOM   11427 C  CZ  . PHE E 1 302 ? 8.244   -7.549  58.595  1.00 21.55  ? 302 PHE E CZ  1 
ATOM   11428 N  N   . THR E 1 303 ? 9.143   -10.247 54.677  1.00 23.45  ? 303 THR E N   1 
ATOM   11429 C  CA  . THR E 1 303 ? 10.423  -9.783  54.184  1.00 24.67  ? 303 THR E CA  1 
ATOM   11430 C  C   . THR E 1 303 ? 10.835  -8.597  55.042  1.00 26.80  ? 303 THR E C   1 
ATOM   11431 O  O   . THR E 1 303 ? 10.339  -7.487  54.836  1.00 27.87  ? 303 THR E O   1 
ATOM   11432 C  CB  . THR E 1 303 ? 10.357  -9.425  52.696  1.00 23.38  ? 303 THR E CB  1 
ATOM   11433 O  OG1 . THR E 1 303 ? 9.414   -8.396  52.461  1.00 23.77  ? 303 THR E OG1 1 
ATOM   11434 C  CG2 . THR E 1 303 ? 9.878   -10.579 51.829  1.00 25.98  ? 303 THR E CG2 1 
ATOM   11435 N  N   . PRO E 1 304 ? 11.764  -8.794  56.011  1.00 27.21  ? 304 PRO E N   1 
ATOM   11436 C  CA  . PRO E 1 304 ? 12.137  -7.728  56.958  1.00 27.63  ? 304 PRO E CA  1 
ATOM   11437 C  C   . PRO E 1 304 ? 12.869  -6.571  56.295  1.00 32.92  ? 304 PRO E C   1 
ATOM   11438 O  O   . PRO E 1 304 ? 13.369  -6.691  55.176  1.00 32.99  ? 304 PRO E O   1 
ATOM   11439 C  CB  . PRO E 1 304 ? 13.046  -8.375  57.979  1.00 26.56  ? 304 PRO E CB  1 
ATOM   11440 C  CG  . PRO E 1 304 ? 12.946  -9.861  57.671  1.00 27.68  ? 304 PRO E CG  1 
ATOM   11441 C  CD  . PRO E 1 304 ? 12.499  -10.043 56.231  1.00 25.52  ? 304 PRO E CD  1 
ATOM   11442 N  N   . ALA E 1 305 ? 12.928  -5.458  57.017  1.00 33.95  ? 305 ALA E N   1 
ATOM   11443 C  CA  . ALA E 1 305 ? 13.816  -4.380  56.639  1.00 35.84  ? 305 ALA E CA  1 
ATOM   11444 C  C   . ALA E 1 305 ? 15.242  -4.914  56.586  1.00 37.22  ? 305 ALA E C   1 
ATOM   11445 O  O   . ALA E 1 305 ? 15.583  -5.870  57.300  1.00 34.57  ? 305 ALA E O   1 
ATOM   11446 C  CB  . ALA E 1 305 ? 13.686  -3.223  57.605  1.00 40.25  ? 305 ALA E CB  1 
ATOM   11447 N  N   . ALA E 1 306 ? 16.041  -4.303  55.694  1.00 37.78  ? 306 ALA E N   1 
ATOM   11448 C  CA  . ALA E 1 306 ? 17.408  -4.743  55.457  1.00 38.78  ? 306 ALA E CA  1 
ATOM   11449 C  C   . ALA E 1 306 ? 18.240  -4.730  56.744  1.00 37.61  ? 306 ALA E C   1 
ATOM   11450 O  O   . ALA E 1 306 ? 18.975  -5.684  56.991  1.00 34.37  ? 306 ALA E O   1 
ATOM   11451 C  CB  . ALA E 1 306 ? 18.029  -3.896  54.383  1.00 36.58  ? 306 ALA E CB  1 
ATOM   11452 N  N   . ASP E 1 307 ? 18.085  -3.671  57.561  1.00 40.28  ? 307 ASP E N   1 
ATOM   11453 C  CA  . ASP E 1 307 ? 18.832  -3.475  58.796  1.00 45.42  ? 307 ASP E CA  1 
ATOM   11454 C  C   . ASP E 1 307 ? 18.636  -4.666  59.726  1.00 51.18  ? 307 ASP E C   1 
ATOM   11455 O  O   . ASP E 1 307 ? 19.587  -5.094  60.388  1.00 50.51  ? 307 ASP E O   1 
ATOM   11456 C  CB  . ASP E 1 307 ? 18.342  -2.296  59.624  1.00 48.00  ? 307 ASP E CB  1 
ATOM   11457 C  CG  . ASP E 1 307 ? 17.641  -1.184  58.860  1.00 62.51  ? 307 ASP E CG  1 
ATOM   11458 O  OD1 . ASP E 1 307 ? 17.170  -1.424  57.729  1.00 78.04  ? 307 ASP E OD1 1 
ATOM   11459 O  OD2 . ASP E 1 307 ? 17.557  -0.055  59.363  1.00 76.83  ? 307 ASP E OD2 1 
ATOM   11460 N  N   . PHE E 1 308 ? 17.386  -5.168  59.781  1.00 48.27  ? 308 PHE E N   1 
ATOM   11461 C  CA  . PHE E 1 308 ? 17.043  -6.280  60.657  1.00 43.66  ? 308 PHE E CA  1 
ATOM   11462 C  C   . PHE E 1 308 ? 17.977  -7.462  60.402  1.00 42.52  ? 308 PHE E C   1 
ATOM   11463 O  O   . PHE E 1 308 ? 18.459  -8.076  61.368  1.00 41.49  ? 308 PHE E O   1 
ATOM   11464 C  CB  . PHE E 1 308 ? 15.560  -6.654  60.522  1.00 43.86  ? 308 PHE E CB  1 
ATOM   11465 C  CG  . PHE E 1 308 ? 15.135  -7.834  61.390  1.00 39.67  ? 308 PHE E CG  1 
ATOM   11466 C  CD1 . PHE E 1 308 ? 15.330  -9.136  60.932  1.00 40.43  ? 308 PHE E CD1 1 
ATOM   11467 C  CD2 . PHE E 1 308 ? 14.580  -7.644  62.656  1.00 35.50  ? 308 PHE E CD2 1 
ATOM   11468 C  CE1 . PHE E 1 308 ? 14.965  -10.222 61.711  1.00 45.73  ? 308 PHE E CE1 1 
ATOM   11469 C  CE2 . PHE E 1 308 ? 14.229  -8.723  63.432  1.00 38.04  ? 308 PHE E CE2 1 
ATOM   11470 C  CZ  . PHE E 1 308 ? 14.411  -10.016 62.958  1.00 42.07  ? 308 PHE E CZ  1 
ATOM   11471 N  N   . LEU E 1 309 ? 18.225  -7.770  59.110  1.00 42.24  ? 309 LEU E N   1 
ATOM   11472 C  CA  . LEU E 1 309 ? 19.039  -8.918  58.742  1.00 43.60  ? 309 LEU E CA  1 
ATOM   11473 C  C   . LEU E 1 309 ? 20.525  -8.663  59.032  1.00 49.63  ? 309 LEU E C   1 
ATOM   11474 O  O   . LEU E 1 309 ? 21.225  -9.600  59.450  1.00 50.40  ? 309 LEU E O   1 
ATOM   11475 C  CB  . LEU E 1 309 ? 18.818  -9.275  57.272  1.00 40.42  ? 309 LEU E CB  1 
ATOM   11476 C  CG  . LEU E 1 309 ? 17.416  -9.724  56.851  1.00 35.42  ? 309 LEU E CG  1 
ATOM   11477 C  CD1 . LEU E 1 309 ? 17.286  -9.823  55.334  1.00 32.30  ? 309 LEU E CD1 1 
ATOM   11478 C  CD2 . LEU E 1 309 ? 17.121  -11.099 57.433  1.00 43.21  ? 309 LEU E CD2 1 
ATOM   11479 N  N   . GLU E 1 310 ? 20.992  -7.414  58.790  1.00 48.31  ? 310 GLU E N   1 
ATOM   11480 C  CA  . GLU E 1 310 ? 22.401  -7.061  58.915  1.00 53.93  ? 310 GLU E CA  1 
ATOM   11481 C  C   . GLU E 1 310 ? 22.852  -7.413  60.333  1.00 59.13  ? 310 GLU E C   1 
ATOM   11482 O  O   . GLU E 1 310 ? 23.910  -8.028  60.488  1.00 55.94  ? 310 GLU E O   1 
ATOM   11483 C  CB  . GLU E 1 310 ? 22.683  -5.615  58.484  1.00 56.51  ? 310 GLU E CB  1 
ATOM   11484 C  CG  . GLU E 1 310 ? 23.993  -5.407  57.715  1.00 60.13  ? 310 GLU E CG  1 
ATOM   11485 C  CD  . GLU E 1 310 ? 24.160  -3.957  57.271  1.00 70.72  ? 310 GLU E CD  1 
ATOM   11486 O  OE1 . GLU E 1 310 ? 25.050  -3.681  56.432  1.00 82.54  ? 310 GLU E OE1 1 
ATOM   11487 O  OE2 . GLU E 1 310 ? 23.399  -3.091  57.787  1.00 66.35  ? 310 GLU E OE2 1 
ATOM   11488 N  N   . ASP E 1 311 ? 21.990  -7.138  61.334  1.00 66.76  ? 311 ASP E N   1 
ATOM   11489 C  CA  . ASP E 1 311 ? 22.353  -7.182  62.746  1.00 71.84  ? 311 ASP E CA  1 
ATOM   11490 C  C   . ASP E 1 311 ? 22.149  -8.545  63.424  1.00 72.83  ? 311 ASP E C   1 
ATOM   11491 O  O   . ASP E 1 311 ? 21.360  -8.590  64.363  1.00 76.43  ? 311 ASP E O   1 
ATOM   11492 C  CB  . ASP E 1 311 ? 21.505  -6.174  63.512  1.00 66.76  ? 311 ASP E CB  1 
ATOM   11493 C  CG  . ASP E 1 311 ? 21.500  -4.750  62.965  1.00 75.42  ? 311 ASP E CG  1 
ATOM   11494 O  OD1 . ASP E 1 311 ? 22.306  -4.422  62.070  1.00 74.50  ? 311 ASP E OD1 1 
ATOM   11495 O  OD2 . ASP E 1 311 ? 20.665  -3.957  63.427  1.00 79.48  ? 311 ASP E OD2 1 
ATOM   11496 N  N   . LEU E 1 312 ? 22.859  -9.627  63.014  1.00 72.63  ? 312 LEU E N   1 
ATOM   11497 C  CA  . LEU E 1 312 ? 22.643  -10.960 63.601  1.00 70.29  ? 312 LEU E CA  1 
ATOM   11498 C  C   . LEU E 1 312 ? 23.998  -11.685 63.864  1.00 62.57  ? 312 LEU E C   1 
ATOM   11499 O  O   . LEU E 1 312 ? 25.085  -11.122 63.571  1.00 54.04  ? 312 LEU E O   1 
ATOM   11500 C  CB  . LEU E 1 312 ? 21.699  -11.920 62.845  1.00 62.77  ? 312 LEU E CB  1 
ATOM   11501 C  CG  . LEU E 1 312 ? 20.430  -11.412 62.132  1.00 52.34  ? 312 LEU E CG  1 
ATOM   11502 C  CD1 . LEU E 1 312 ? 19.827  -12.647 61.489  1.00 49.67  ? 312 LEU E CD1 1 
ATOM   11503 C  CD2 . LEU E 1 312 ? 19.338  -10.724 62.921  1.00 48.32  ? 312 LEU E CD2 1 
ATOM   11504 N  N   . PRO F 1 8   ? 19.209  22.942  51.356  1.00 71.74  ? 8   PRO F N   1 
ATOM   11505 C  CA  . PRO F 1 8   ? 20.580  23.201  50.868  1.00 73.55  ? 8   PRO F CA  1 
ATOM   11506 C  C   . PRO F 1 8   ? 21.137  22.219  49.812  1.00 69.61  ? 8   PRO F C   1 
ATOM   11507 O  O   . PRO F 1 8   ? 21.257  21.036  50.120  1.00 62.07  ? 8   PRO F O   1 
ATOM   11508 C  CB  . PRO F 1 8   ? 21.370  23.161  52.213  1.00 66.42  ? 8   PRO F CB  1 
ATOM   11509 C  CG  . PRO F 1 8   ? 20.586  22.143  53.067  1.00 70.77  ? 8   PRO F CG  1 
ATOM   11510 C  CD  . PRO F 1 8   ? 19.153  22.038  52.506  1.00 69.84  ? 8   PRO F CD  1 
ATOM   11511 N  N   . GLU F 1 9   ? 21.462  22.712  48.584  1.00 71.73  ? 9   GLU F N   1 
ATOM   11512 C  CA  . GLU F 1 9   ? 21.761  21.926  47.370  1.00 58.07  ? 9   GLU F CA  1 
ATOM   11513 C  C   . GLU F 1 9   ? 23.255  21.568  47.372  1.00 48.40  ? 9   GLU F C   1 
ATOM   11514 O  O   . GLU F 1 9   ? 24.102  22.470  47.266  1.00 39.36  ? 9   GLU F O   1 
ATOM   11515 C  CB  . GLU F 1 9   ? 21.381  22.624  46.034  1.00 43.83  ? 9   GLU F CB  1 
ATOM   11516 N  N   . PRO F 1 10  ? 23.652  20.275  47.516  1.00 38.98  ? 10  PRO F N   1 
ATOM   11517 C  CA  . PRO F 1 10  ? 25.070  19.887  47.459  1.00 40.98  ? 10  PRO F CA  1 
ATOM   11518 C  C   . PRO F 1 10  ? 25.599  19.900  46.028  1.00 41.15  ? 10  PRO F C   1 
ATOM   11519 O  O   . PRO F 1 10  ? 24.818  19.829  45.066  1.00 37.37  ? 10  PRO F O   1 
ATOM   11520 C  CB  . PRO F 1 10  ? 25.086  18.441  48.036  1.00 39.03  ? 10  PRO F CB  1 
ATOM   11521 C  CG  . PRO F 1 10  ? 23.758  17.882  47.616  1.00 37.85  ? 10  PRO F CG  1 
ATOM   11522 C  CD  . PRO F 1 10  ? 22.794  19.108  47.741  1.00 37.67  ? 10  PRO F CD  1 
ATOM   11523 N  N   . GLN F 1 11  ? 26.936  19.892  45.891  1.00 42.52  ? 11  GLN F N   1 
ATOM   11524 C  CA  . GLN F 1 11  ? 27.543  19.583  44.598  1.00 35.59  ? 11  GLN F CA  1 
ATOM   11525 C  C   . GLN F 1 11  ? 27.263  18.119  44.246  1.00 33.80  ? 11  GLN F C   1 
ATOM   11526 O  O   . GLN F 1 11  ? 26.685  17.391  45.052  1.00 30.83  ? 11  GLN F O   1 
ATOM   11527 C  CB  . GLN F 1 11  ? 29.038  19.866  44.645  1.00 33.05  ? 11  GLN F CB  1 
ATOM   11528 C  CG  . GLN F 1 11  ? 29.361  21.348  44.706  1.00 30.14  ? 11  GLN F CG  1 
ATOM   11529 C  CD  . GLN F 1 11  ? 30.843  21.576  44.537  1.00 29.70  ? 11  GLN F CD  1 
ATOM   11530 O  OE1 . GLN F 1 11  ? 31.428  21.415  43.461  1.00 30.08  ? 11  GLN F OE1 1 
ATOM   11531 N  NE2 . GLN F 1 11  ? 31.480  21.948  45.622  1.00 33.27  ? 11  GLN F NE2 1 
ATOM   11532 N  N   . MET F 1 12  ? 27.704  17.678  43.065  1.00 33.73  ? 12  MET F N   1 
ATOM   11533 C  CA  . MET F 1 12  ? 27.423  16.330  42.608  1.00 33.53  ? 12  MET F CA  1 
ATOM   11534 C  C   . MET F 1 12  ? 28.423  15.317  43.168  1.00 30.01  ? 12  MET F C   1 
ATOM   11535 O  O   . MET F 1 12  ? 29.016  14.507  42.437  1.00 29.46  ? 12  MET F O   1 
ATOM   11536 C  CB  . MET F 1 12  ? 27.408  16.243  41.081  1.00 41.69  ? 12  MET F CB  1 
ATOM   11537 C  CG  . MET F 1 12  ? 26.605  15.035  40.590  1.00 51.68  ? 12  MET F CG  1 
ATOM   11538 S  SD  . MET F 1 12  ? 24.842  15.426  40.560  1.00 60.31  ? 12  MET F SD  1 
ATOM   11539 C  CE  . MET F 1 12  ? 24.334  16.944  41.406  1.00 53.10  ? 12  MET F CE  1 
ATOM   11540 N  N   . VAL F 1 13  ? 28.535  15.311  44.487  1.00 28.60  ? 13  VAL F N   1 
ATOM   11541 C  CA  . VAL F 1 13  ? 29.387  14.357  45.165  1.00 31.82  ? 13  VAL F CA  1 
ATOM   11542 C  C   . VAL F 1 13  ? 28.909  12.923  44.898  1.00 34.20  ? 13  VAL F C   1 
ATOM   11543 O  O   . VAL F 1 13  ? 29.732  12.068  44.604  1.00 30.33  ? 13  VAL F O   1 
ATOM   11544 C  CB  . VAL F 1 13  ? 29.482  14.684  46.667  1.00 30.42  ? 13  VAL F CB  1 
ATOM   11545 C  CG1 . VAL F 1 13  ? 30.307  13.618  47.380  1.00 34.77  ? 13  VAL F CG1 1 
ATOM   11546 C  CG2 . VAL F 1 13  ? 30.026  16.092  46.909  1.00 28.75  ? 13  VAL F CG2 1 
ATOM   11547 N  N   . LEU F 1 14  ? 27.600  12.663  45.027  1.00 38.61  ? 14  LEU F N   1 
ATOM   11548 C  CA  . LEU F 1 14  ? 27.042  11.339  44.773  1.00 45.94  ? 14  LEU F CA  1 
ATOM   11549 C  C   . LEU F 1 14  ? 26.683  11.302  43.294  1.00 48.60  ? 14  LEU F C   1 
ATOM   11550 O  O   . LEU F 1 14  ? 25.627  11.744  42.906  1.00 51.91  ? 14  LEU F O   1 
ATOM   11551 C  CB  . LEU F 1 14  ? 25.840  11.043  45.671  1.00 46.55  ? 14  LEU F CB  1 
ATOM   11552 C  CG  . LEU F 1 14  ? 25.942  11.560  47.121  1.00 54.86  ? 14  LEU F CG  1 
ATOM   11553 C  CD1 . LEU F 1 14  ? 24.670  11.701  47.982  1.00 58.99  ? 14  LEU F CD1 1 
ATOM   11554 C  CD2 . LEU F 1 14  ? 26.869  10.644  47.841  1.00 61.96  ? 14  LEU F CD2 1 
ATOM   11555 N  N   . SER F 1 15  ? 27.621  10.904  42.448  1.00 53.29  ? 15  SER F N   1 
ATOM   11556 C  CA  . SER F 1 15  ? 27.363  10.821  41.024  1.00 53.05  ? 15  SER F CA  1 
ATOM   11557 C  C   . SER F 1 15  ? 26.989  9.372   40.655  1.00 52.56  ? 15  SER F C   1 
ATOM   11558 O  O   . SER F 1 15  ? 27.391  8.402   41.297  1.00 39.85  ? 15  SER F O   1 
ATOM   11559 C  CB  . SER F 1 15  ? 28.585  11.387  40.256  1.00 54.36  ? 15  SER F CB  1 
ATOM   11560 O  OG  . SER F 1 15  ? 28.655  11.000  38.876  1.00 56.80  ? 15  SER F OG  1 
ATOM   11561 N  N   . PRO F 1 16  ? 26.196  9.152   39.581  1.00 68.99  ? 16  PRO F N   1 
ATOM   11562 C  CA  . PRO F 1 16  ? 26.122  7.838   38.936  1.00 65.50  ? 16  PRO F CA  1 
ATOM   11563 C  C   . PRO F 1 16  ? 27.516  7.311   38.644  1.00 62.00  ? 16  PRO F C   1 
ATOM   11564 O  O   . PRO F 1 16  ? 28.480  8.072   38.614  1.00 69.12  ? 16  PRO F O   1 
ATOM   11565 C  CB  . PRO F 1 16  ? 25.381  8.082   37.608  1.00 71.19  ? 16  PRO F CB  1 
ATOM   11566 C  CG  . PRO F 1 16  ? 25.291  9.596   37.475  1.00 75.47  ? 16  PRO F CG  1 
ATOM   11567 C  CD  . PRO F 1 16  ? 25.368  10.156  38.891  1.00 73.98  ? 16  PRO F CD  1 
ATOM   11568 N  N   . LEU F 1 17  ? 27.592  6.017   38.363  1.00 56.86  ? 17  LEU F N   1 
ATOM   11569 C  CA  . LEU F 1 17  ? 28.823  5.435   37.862  1.00 61.41  ? 17  LEU F CA  1 
ATOM   11570 C  C   . LEU F 1 17  ? 29.153  6.127   36.536  1.00 52.47  ? 17  LEU F C   1 
ATOM   11571 O  O   . LEU F 1 17  ? 28.286  6.352   35.680  1.00 46.18  ? 17  LEU F O   1 
ATOM   11572 C  CB  . LEU F 1 17  ? 28.834  3.905   37.751  1.00 68.87  ? 17  LEU F CB  1 
ATOM   11573 C  CG  . LEU F 1 17  ? 28.811  3.110   39.073  1.00 73.65  ? 17  LEU F CG  1 
ATOM   11574 C  CD1 . LEU F 1 17  ? 29.086  1.628   38.766  1.00 71.18  ? 17  LEU F CD1 1 
ATOM   11575 C  CD2 . LEU F 1 17  ? 29.741  3.617   40.190  1.00 68.83  ? 17  LEU F CD2 1 
ATOM   11576 N  N   . THR F 1 18  ? 30.422  6.552   36.485  1.00 39.23  ? 18  THR F N   1 
ATOM   11577 C  CA  . THR F 1 18  ? 31.021  7.264   35.383  1.00 35.03  ? 18  THR F CA  1 
ATOM   11578 C  C   . THR F 1 18  ? 32.312  6.510   35.139  1.00 34.06  ? 18  THR F C   1 
ATOM   11579 O  O   . THR F 1 18  ? 32.931  5.995   36.062  1.00 29.79  ? 18  THR F O   1 
ATOM   11580 C  CB  . THR F 1 18  ? 31.282  8.752   35.670  1.00 31.97  ? 18  THR F CB  1 
ATOM   11581 O  OG1 . THR F 1 18  ? 32.109  8.847   36.818  1.00 33.61  ? 18  THR F OG1 1 
ATOM   11582 C  CG2 . THR F 1 18  ? 30.056  9.584   35.988  1.00 32.81  ? 18  THR F CG2 1 
ATOM   11583 N  N   . SER F 1 19  ? 32.729  6.496   33.890  1.00 34.97  ? 19  SER F N   1 
ATOM   11584 C  CA  . SER F 1 19  ? 33.853  5.687   33.500  1.00 34.01  ? 19  SER F CA  1 
ATOM   11585 C  C   . SER F 1 19  ? 35.016  6.566   33.068  1.00 28.10  ? 19  SER F C   1 
ATOM   11586 O  O   . SER F 1 19  ? 36.032  6.004   32.692  1.00 29.68  ? 19  SER F O   1 
ATOM   11587 C  CB  . SER F 1 19  ? 33.394  4.790   32.410  1.00 36.31  ? 19  SER F CB  1 
ATOM   11588 O  OG  . SER F 1 19  ? 32.666  5.629   31.527  1.00 41.02  ? 19  SER F OG  1 
ATOM   11589 N  N   . ALA F 1 20  ? 34.921  7.903   33.167  1.00 24.13  ? 20  ALA F N   1 
ATOM   11590 C  CA  . ALA F 1 20  ? 36.077  8.745   32.877  1.00 21.56  ? 20  ALA F CA  1 
ATOM   11591 C  C   . ALA F 1 20  ? 36.175  9.864   33.876  1.00 21.41  ? 20  ALA F C   1 
ATOM   11592 O  O   . ALA F 1 20  ? 35.153  10.341  34.331  1.00 21.25  ? 20  ALA F O   1 
ATOM   11593 C  CB  . ALA F 1 20  ? 35.999  9.346   31.506  1.00 23.25  ? 20  ALA F CB  1 
ATOM   11594 N  N   . ALA F 1 21  ? 37.404  10.289  34.195  1.00 21.00  ? 21  ALA F N   1 
ATOM   11595 C  CA  . ALA F 1 21  ? 37.557  11.419  35.093  1.00 19.55  ? 21  ALA F CA  1 
ATOM   11596 C  C   . ALA F 1 21  ? 38.814  12.185  34.735  1.00 20.48  ? 21  ALA F C   1 
ATOM   11597 O  O   . ALA F 1 21  ? 39.774  11.622  34.212  1.00 21.54  ? 21  ALA F O   1 
ATOM   11598 C  CB  . ALA F 1 21  ? 37.596  10.986  36.519  1.00 19.14  ? 21  ALA F CB  1 
ATOM   11599 N  N   . ILE F 1 22  ? 38.777  13.471  35.057  1.00 18.79  ? 22  ILE F N   1 
ATOM   11600 C  CA  . ILE F 1 22  ? 39.988  14.267  35.177  1.00 19.51  ? 22  ILE F CA  1 
ATOM   11601 C  C   . ILE F 1 22  ? 40.018  14.845  36.585  1.00 18.13  ? 22  ILE F C   1 
ATOM   11602 O  O   . ILE F 1 22  ? 39.065  15.479  37.066  1.00 20.66  ? 22  ILE F O   1 
ATOM   11603 C  CB  . ILE F 1 22  ? 40.047  15.363  34.096  1.00 19.70  ? 22  ILE F CB  1 
ATOM   11604 C  CG1 . ILE F 1 22  ? 40.278  14.760  32.733  1.00 21.91  ? 22  ILE F CG1 1 
ATOM   11605 C  CG2 . ILE F 1 22  ? 41.112  16.400  34.417  1.00 19.85  ? 22  ILE F CG2 1 
ATOM   11606 C  CD1 . ILE F 1 22  ? 40.103  15.736  31.588  1.00 22.27  ? 22  ILE F CD1 1 
ATOM   11607 N  N   . PHE F 1 23  ? 41.155  14.645  37.232  1.00 19.39  ? 23  PHE F N   1 
ATOM   11608 C  CA  . PHE F 1 23  ? 41.455  15.277  38.505  1.00 19.04  ? 23  PHE F CA  1 
ATOM   11609 C  C   . PHE F 1 23  ? 42.456  16.383  38.227  1.00 19.53  ? 23  PHE F C   1 
ATOM   11610 O  O   . PHE F 1 23  ? 43.505  16.165  37.650  1.00 18.99  ? 23  PHE F O   1 
ATOM   11611 C  CB  . PHE F 1 23  ? 42.105  14.309  39.494  1.00 20.78  ? 23  PHE F CB  1 
ATOM   11612 C  CG  . PHE F 1 23  ? 41.256  13.072  39.740  1.00 21.67  ? 23  PHE F CG  1 
ATOM   11613 C  CD1 . PHE F 1 23  ? 40.294  13.052  40.742  1.00 23.81  ? 23  PHE F CD1 1 
ATOM   11614 C  CD2 . PHE F 1 23  ? 41.394  11.957  38.945  1.00 22.12  ? 23  PHE F CD2 1 
ATOM   11615 C  CE1 . PHE F 1 23  ? 39.515  11.921  40.971  1.00 22.33  ? 23  PHE F CE1 1 
ATOM   11616 C  CE2 . PHE F 1 23  ? 40.599  10.844  39.152  1.00 22.86  ? 23  PHE F CE2 1 
ATOM   11617 C  CZ  . PHE F 1 23  ? 39.657  10.825  40.172  1.00 22.26  ? 23  PHE F CZ  1 
ATOM   11618 N  N   . LEU F 1 24  ? 42.126  17.584  38.639  1.00 20.29  ? 24  LEU F N   1 
ATOM   11619 C  CA  . LEU F 1 24  ? 43.003  18.711  38.402  1.00 21.78  ? 24  LEU F CA  1 
ATOM   11620 C  C   . LEU F 1 24  ? 43.269  19.408  39.739  1.00 20.19  ? 24  LEU F C   1 
ATOM   11621 O  O   . LEU F 1 24  ? 42.334  19.726  40.463  1.00 22.68  ? 24  LEU F O   1 
ATOM   11622 C  CB  . LEU F 1 24  ? 42.186  19.529  37.413  1.00 23.47  ? 24  LEU F CB  1 
ATOM   11623 C  CG  . LEU F 1 24  ? 42.905  20.635  36.667  1.00 28.81  ? 24  LEU F CG  1 
ATOM   11624 C  CD1 . LEU F 1 24  ? 44.106  20.132  35.859  1.00 35.04  ? 24  LEU F CD1 1 
ATOM   11625 C  CD2 . LEU F 1 24  ? 41.838  21.154  35.765  1.00 32.15  ? 24  LEU F CD2 1 
ATOM   11626 N  N   . VAL F 1 25  ? 44.535  19.538  40.125  1.00 21.31  ? 25  VAL F N   1 
ATOM   11627 C  CA  . VAL F 1 25  ? 44.910  20.221  41.349  1.00 21.71  ? 25  VAL F CA  1 
ATOM   11628 C  C   . VAL F 1 25  ? 45.776  21.415  40.985  1.00 20.47  ? 25  VAL F C   1 
ATOM   11629 O  O   . VAL F 1 25  ? 46.766  21.245  40.313  1.00 19.03  ? 25  VAL F O   1 
ATOM   11630 C  CB  . VAL F 1 25  ? 45.651  19.282  42.314  1.00 23.59  ? 25  VAL F CB  1 
ATOM   11631 C  CG1 . VAL F 1 25  ? 46.075  20.000  43.604  1.00 26.54  ? 25  VAL F CG1 1 
ATOM   11632 C  CG2 . VAL F 1 25  ? 44.785  18.099  42.693  1.00 23.19  ? 25  VAL F CG2 1 
ATOM   11633 N  N   . VAL F 1 26  ? 45.384  22.595  41.439  1.00 20.33  ? 26  VAL F N   1 
ATOM   11634 C  CA  . VAL F 1 26  ? 46.174  23.779  41.212  1.00 25.25  ? 26  VAL F CA  1 
ATOM   11635 C  C   . VAL F 1 26  ? 46.410  24.533  42.509  1.00 26.52  ? 26  VAL F C   1 
ATOM   11636 O  O   . VAL F 1 26  ? 45.640  24.380  43.456  1.00 24.34  ? 26  VAL F O   1 
ATOM   11637 C  CB  . VAL F 1 26  ? 45.504  24.719  40.192  1.00 25.79  ? 26  VAL F CB  1 
ATOM   11638 C  CG1 . VAL F 1 26  ? 45.283  23.957  38.886  1.00 31.06  ? 26  VAL F CG1 1 
ATOM   11639 C  CG2 . VAL F 1 26  ? 44.246  25.373  40.735  1.00 23.73  ? 26  VAL F CG2 1 
ATOM   11640 N  N   . THR F 1 27  ? 47.442  25.409  42.473  1.00 28.85  ? 27  THR F N   1 
ATOM   11641 C  CA  . THR F 1 27  ? 47.649  26.417  43.513  1.00 27.54  ? 27  THR F CA  1 
ATOM   11642 C  C   . THR F 1 27  ? 47.329  27.808  42.981  1.00 26.73  ? 27  THR F C   1 
ATOM   11643 O  O   . THR F 1 27  ? 47.479  28.080  41.801  1.00 28.29  ? 27  THR F O   1 
ATOM   11644 C  CB  . THR F 1 27  ? 49.070  26.300  44.044  1.00 26.92  ? 27  THR F CB  1 
ATOM   11645 O  OG1 . THR F 1 27  ? 49.984  26.443  42.968  1.00 24.59  ? 27  THR F OG1 1 
ATOM   11646 C  CG2 . THR F 1 27  ? 49.271  24.931  44.661  1.00 28.67  ? 27  THR F CG2 1 
ATOM   11647 N  N   . ILE F 1 28  ? 46.857  28.669  43.875  1.00 26.86  ? 28  ILE F N   1 
ATOM   11648 C  CA  . ILE F 1 28  ? 46.557  30.047  43.535  1.00 29.01  ? 28  ILE F CA  1 
ATOM   11649 C  C   . ILE F 1 28  ? 47.841  30.885  43.674  1.00 34.69  ? 28  ILE F C   1 
ATOM   11650 O  O   . ILE F 1 28  ? 48.476  30.933  44.737  1.00 32.72  ? 28  ILE F O   1 
ATOM   11651 C  CB  . ILE F 1 28  ? 45.411  30.553  44.434  1.00 30.32  ? 28  ILE F CB  1 
ATOM   11652 C  CG1 . ILE F 1 28  ? 44.202  29.627  44.385  1.00 32.61  ? 28  ILE F CG1 1 
ATOM   11653 C  CG2 . ILE F 1 28  ? 45.016  31.981  44.071  1.00 29.71  ? 28  ILE F CG2 1 
ATOM   11654 C  CD1 . ILE F 1 28  ? 43.097  29.988  45.359  1.00 34.66  ? 28  ILE F CD1 1 
ATOM   11655 N  N   . ASP F 1 29  ? 48.236  31.564  42.586  1.00 36.95  ? 29  ASP F N   1 
ATOM   11656 C  CA  . ASP F 1 29  ? 49.363  32.479  42.618  1.00 37.70  ? 29  ASP F CA  1 
ATOM   11657 C  C   . ASP F 1 29  ? 48.997  33.692  43.461  1.00 39.64  ? 29  ASP F C   1 
ATOM   11658 O  O   . ASP F 1 29  ? 47.822  33.990  43.679  1.00 37.29  ? 29  ASP F O   1 
ATOM   11659 C  CB  . ASP F 1 29  ? 49.731  32.942  41.224  1.00 38.89  ? 29  ASP F CB  1 
ATOM   11660 C  CG  . ASP F 1 29  ? 50.094  31.822  40.270  1.00 37.84  ? 29  ASP F CG  1 
ATOM   11661 O  OD1 . ASP F 1 29  ? 50.209  30.648  40.755  1.00 30.88  ? 29  ASP F OD1 1 
ATOM   11662 O  OD2 . ASP F 1 29  ? 50.225  32.155  39.066  1.00 44.85  ? 29  ASP F OD2 1 
ATOM   11663 N  N   . SER F 1 30  ? 50.026  34.402  43.919  1.00 38.73  ? 30  SER F N   1 
ATOM   11664 C  CA  . SER F 1 30  ? 49.792  35.628  44.644  1.00 39.25  ? 30  SER F CA  1 
ATOM   11665 C  C   . SER F 1 30  ? 49.009  36.587  43.753  1.00 37.33  ? 30  SER F C   1 
ATOM   11666 O  O   . SER F 1 30  ? 49.305  36.689  42.578  1.00 37.45  ? 30  SER F O   1 
ATOM   11667 C  CB  . SER F 1 30  ? 51.100  36.185  45.037  1.00 47.30  ? 30  SER F CB  1 
ATOM   11668 O  OG  . SER F 1 30  ? 50.873  37.191  46.004  1.00 65.10  ? 30  SER F OG  1 
ATOM   11669 N  N   . GLY F 1 31  ? 47.965  37.233  44.268  1.00 39.50  ? 31  GLY F N   1 
ATOM   11670 C  CA  . GLY F 1 31  ? 47.208  38.205  43.488  1.00 35.27  ? 31  GLY F CA  1 
ATOM   11671 C  C   . GLY F 1 31  ? 46.147  37.577  42.600  1.00 35.77  ? 31  GLY F C   1 
ATOM   11672 O  O   . GLY F 1 31  ? 45.367  38.300  42.037  1.00 44.27  ? 31  GLY F O   1 
ATOM   11673 N  N   . GLY F 1 32  ? 46.082  36.245  42.506  1.00 42.70  ? 32  GLY F N   1 
ATOM   11674 C  CA  . GLY F 1 32  ? 45.086  35.549  41.688  1.00 43.84  ? 32  GLY F CA  1 
ATOM   11675 C  C   . GLY F 1 32  ? 43.681  35.410  42.321  1.00 40.75  ? 32  GLY F C   1 
ATOM   11676 O  O   . GLY F 1 32  ? 42.745  34.913  41.693  1.00 31.30  ? 32  GLY F O   1 
ATOM   11677 N  N   . GLU F 1 33  ? 43.504  35.858  43.566  1.00 37.95  ? 33  GLU F N   1 
ATOM   11678 C  CA  . GLU F 1 33  ? 42.316  35.518  44.319  1.00 33.10  ? 33  GLU F CA  1 
ATOM   11679 C  C   . GLU F 1 33  ? 41.036  36.053  43.674  1.00 35.23  ? 33  GLU F C   1 
ATOM   11680 O  O   . GLU F 1 33  ? 39.998  35.414  43.816  1.00 31.35  ? 33  GLU F O   1 
ATOM   11681 C  CB  . GLU F 1 33  ? 42.472  36.040  45.739  1.00 31.55  ? 33  GLU F CB  1 
ATOM   11682 C  CG  . GLU F 1 33  ? 43.523  35.294  46.547  1.00 32.23  ? 33  GLU F CG  1 
ATOM   11683 C  CD  . GLU F 1 33  ? 44.901  35.865  46.434  1.00 34.81  ? 33  GLU F CD  1 
ATOM   11684 O  OE1 . GLU F 1 33  ? 45.112  36.846  45.711  1.00 35.45  ? 33  GLU F OE1 1 
ATOM   11685 O  OE2 . GLU F 1 33  ? 45.749  35.310  47.130  1.00 42.32  ? 33  GLU F OE2 1 
ATOM   11686 N  N   . ASP F 1 34  ? 41.064  37.230  43.025  1.00 40.68  ? 34  ASP F N   1 
ATOM   11687 C  CA  . ASP F 1 34  ? 39.833  37.772  42.441  1.00 43.41  ? 34  ASP F CA  1 
ATOM   11688 C  C   . ASP F 1 34  ? 39.377  36.912  41.259  1.00 39.31  ? 34  ASP F C   1 
ATOM   11689 O  O   . ASP F 1 34  ? 38.181  36.664  41.080  1.00 32.14  ? 34  ASP F O   1 
ATOM   11690 C  CB  . ASP F 1 34  ? 39.986  39.218  41.983  1.00 47.78  ? 34  ASP F CB  1 
ATOM   11691 C  CG  . ASP F 1 34  ? 39.798  40.235  43.100  1.00 55.37  ? 34  ASP F CG  1 
ATOM   11692 O  OD1 . ASP F 1 34  ? 39.157  39.883  44.107  1.00 59.66  ? 34  ASP F OD1 1 
ATOM   11693 O  OD2 . ASP F 1 34  ? 40.347  41.339  42.999  1.00 54.53  ? 34  ASP F OD2 1 
ATOM   11694 N  N   . THR F 1 35  ? 40.355  36.498  40.445  1.00 33.24  ? 35  THR F N   1 
ATOM   11695 C  CA  . THR F 1 35  ? 40.054  35.669  39.307  1.00 32.72  ? 35  THR F CA  1 
ATOM   11696 C  C   . THR F 1 35  ? 39.425  34.363  39.764  1.00 33.27  ? 35  THR F C   1 
ATOM   11697 O  O   . THR F 1 35  ? 38.460  33.953  39.153  1.00 36.88  ? 35  THR F O   1 
ATOM   11698 C  CB  . THR F 1 35  ? 41.293  35.382  38.478  1.00 33.44  ? 35  THR F CB  1 
ATOM   11699 O  OG1 . THR F 1 35  ? 41.684  36.694  38.117  1.00 33.80  ? 35  THR F OG1 1 
ATOM   11700 C  CG2 . THR F 1 35  ? 40.952  34.561  37.251  1.00 32.33  ? 35  THR F CG2 1 
ATOM   11701 N  N   . VAL F 1 36  ? 39.990  33.707  40.781  1.00 31.62  ? 36  VAL F N   1 
ATOM   11702 C  CA  . VAL F 1 36  ? 39.449  32.454  41.309  1.00 30.77  ? 36  VAL F CA  1 
ATOM   11703 C  C   . VAL F 1 36  ? 38.032  32.646  41.885  1.00 32.02  ? 36  VAL F C   1 
ATOM   11704 O  O   . VAL F 1 36  ? 37.138  31.837  41.684  1.00 32.14  ? 36  VAL F O   1 
ATOM   11705 C  CB  . VAL F 1 36  ? 40.396  31.886  42.381  1.00 29.29  ? 36  VAL F CB  1 
ATOM   11706 C  CG1 . VAL F 1 36  ? 39.766  30.717  43.114  1.00 26.52  ? 36  VAL F CG1 1 
ATOM   11707 C  CG2 . VAL F 1 36  ? 41.765  31.508  41.797  1.00 31.50  ? 36  VAL F CG2 1 
ATOM   11708 N  N   . ARG F 1 37  ? 37.786  33.738  42.596  1.00 32.39  ? 37  ARG F N   1 
ATOM   11709 C  CA  . ARG F 1 37  ? 36.450  34.016  43.098  1.00 37.35  ? 37  ARG F CA  1 
ATOM   11710 C  C   . ARG F 1 37  ? 35.439  34.083  41.959  1.00 33.53  ? 37  ARG F C   1 
ATOM   11711 O  O   . ARG F 1 37  ? 34.363  33.523  42.124  1.00 34.42  ? 37  ARG F O   1 
ATOM   11712 C  CB  . ARG F 1 37  ? 36.338  35.324  43.896  1.00 43.96  ? 37  ARG F CB  1 
ATOM   11713 C  CG  . ARG F 1 37  ? 36.417  35.150  45.400  1.00 44.40  ? 37  ARG F CG  1 
ATOM   11714 C  CD  . ARG F 1 37  ? 36.382  36.484  46.087  1.00 50.61  ? 37  ARG F CD  1 
ATOM   11715 N  NE  . ARG F 1 37  ? 37.507  36.431  47.027  1.00 53.44  ? 37  ARG F NE  1 
ATOM   11716 C  CZ  . ARG F 1 37  ? 38.599  37.208  47.079  1.00 55.63  ? 37  ARG F CZ  1 
ATOM   11717 N  NH1 . ARG F 1 37  ? 38.840  38.128  46.168  1.00 57.71  ? 37  ARG F NH1 1 
ATOM   11718 N  NH2 . ARG F 1 37  ? 39.481  37.068  48.052  1.00 53.23  ? 37  ARG F NH2 1 
ATOM   11719 N  N   . ASP F 1 38  ? 35.761  34.786  40.860  1.00 33.98  ? 38  ASP F N   1 
ATOM   11720 C  CA  . ASP F 1 38  ? 34.863  34.864  39.705  1.00 42.07  ? 38  ASP F CA  1 
ATOM   11721 C  C   . ASP F 1 38  ? 34.557  33.499  39.121  1.00 32.14  ? 38  ASP F C   1 
ATOM   11722 O  O   . ASP F 1 38  ? 33.417  33.212  38.784  1.00 33.18  ? 38  ASP F O   1 
ATOM   11723 C  CB  . ASP F 1 38  ? 35.372  35.577  38.460  1.00 44.86  ? 38  ASP F CB  1 
ATOM   11724 C  CG  . ASP F 1 38  ? 35.286  37.080  38.529  1.00 52.34  ? 38  ASP F CG  1 
ATOM   11725 O  OD1 . ASP F 1 38  ? 34.302  37.604  39.090  1.00 51.43  ? 38  ASP F OD1 1 
ATOM   11726 O  OD2 . ASP F 1 38  ? 36.223  37.689  38.026  1.00 72.04  ? 38  ASP F OD2 1 
ATOM   11727 N  N   . LEU F 1 39  ? 35.598  32.693  38.955  1.00 31.16  ? 39  LEU F N   1 
ATOM   11728 C  CA  . LEU F 1 39  ? 35.427  31.387  38.343  1.00 29.05  ? 39  LEU F CA  1 
ATOM   11729 C  C   . LEU F 1 39  ? 34.551  30.508  39.229  1.00 30.79  ? 39  LEU F C   1 
ATOM   11730 O  O   . LEU F 1 39  ? 33.696  29.774  38.734  1.00 30.86  ? 39  LEU F O   1 
ATOM   11731 C  CB  . LEU F 1 39  ? 36.826  30.837  38.139  1.00 28.60  ? 39  LEU F CB  1 
ATOM   11732 C  CG  . LEU F 1 39  ? 36.942  29.535  37.370  1.00 30.37  ? 39  LEU F CG  1 
ATOM   11733 C  CD1 . LEU F 1 39  ? 36.746  28.403  38.348  1.00 30.79  ? 39  LEU F CD1 1 
ATOM   11734 C  CD2 . LEU F 1 39  ? 35.936  29.488  36.218  1.00 33.94  ? 39  LEU F CD2 1 
ATOM   11735 N  N   . LEU F 1 40  ? 34.755  30.577  40.548  1.00 30.64  ? 40  LEU F N   1 
ATOM   11736 C  CA  . LEU F 1 40  ? 33.960  29.743  41.432  1.00 27.10  ? 40  LEU F CA  1 
ATOM   11737 C  C   . LEU F 1 40  ? 32.474  30.054  41.261  1.00 28.68  ? 40  LEU F C   1 
ATOM   11738 O  O   . LEU F 1 40  ? 31.615  29.166  41.344  1.00 27.56  ? 40  LEU F O   1 
ATOM   11739 C  CB  . LEU F 1 40  ? 34.449  29.912  42.863  1.00 25.34  ? 40  LEU F CB  1 
ATOM   11740 C  CG  . LEU F 1 40  ? 35.824  29.312  43.150  1.00 26.00  ? 40  LEU F CG  1 
ATOM   11741 C  CD1 . LEU F 1 40  ? 36.126  29.476  44.583  1.00 26.00  ? 40  LEU F CD1 1 
ATOM   11742 C  CD2 . LEU F 1 40  ? 35.938  27.844  42.784  1.00 27.32  ? 40  LEU F CD2 1 
ATOM   11743 N  N   . SER F 1 41  ? 32.150  31.324  41.008  1.00 28.45  ? 41  SER F N   1 
ATOM   11744 C  CA  . SER F 1 41  ? 30.745  31.658  40.879  1.00 33.66  ? 41  SER F CA  1 
ATOM   11745 C  C   . SER F 1 41  ? 30.193  31.208  39.521  1.00 32.08  ? 41  SER F C   1 
ATOM   11746 O  O   . SER F 1 41  ? 28.980  31.188  39.356  1.00 30.10  ? 41  SER F O   1 
ATOM   11747 C  CB  . SER F 1 41  ? 30.471  33.104  41.128  1.00 33.32  ? 41  SER F CB  1 
ATOM   11748 O  OG  . SER F 1 41  ? 31.018  33.836  40.059  1.00 34.01  ? 41  SER F OG  1 
ATOM   11749 N  N   . ASP F 1 42  ? 31.052  30.844  38.559  1.00 29.60  ? 42  ASP F N   1 
ATOM   11750 C  CA  . ASP F 1 42  ? 30.556  30.472  37.240  1.00 27.28  ? 42  ASP F CA  1 
ATOM   11751 C  C   . ASP F 1 42  ? 30.675  28.972  36.963  1.00 27.87  ? 42  ASP F C   1 
ATOM   11752 O  O   . ASP F 1 42  ? 30.248  28.499  35.910  1.00 25.41  ? 42  ASP F O   1 
ATOM   11753 C  CB  . ASP F 1 42  ? 31.270  31.234  36.141  1.00 27.90  ? 42  ASP F CB  1 
ATOM   11754 C  CG  . ASP F 1 42  ? 30.921  32.705  36.002  1.00 29.55  ? 42  ASP F CG  1 
ATOM   11755 O  OD1 . ASP F 1 42  ? 29.748  33.091  36.244  1.00 35.99  ? 42  ASP F OD1 1 
ATOM   11756 O  OD2 . ASP F 1 42  ? 31.815  33.450  35.576  1.00 36.20  ? 42  ASP F OD2 1 
ATOM   11757 N  N   . VAL F 1 43  ? 31.291  28.218  37.877  1.00 23.56  ? 43  VAL F N   1 
ATOM   11758 C  CA  . VAL F 1 43  ? 31.717  26.886  37.508  1.00 23.37  ? 43  VAL F CA  1 
ATOM   11759 C  C   . VAL F 1 43  ? 30.476  26.020  37.263  1.00 24.49  ? 43  VAL F C   1 
ATOM   11760 O  O   . VAL F 1 43  ? 30.498  25.206  36.339  1.00 26.87  ? 43  VAL F O   1 
ATOM   11761 C  CB  . VAL F 1 43  ? 32.736  26.345  38.537  1.00 25.04  ? 43  VAL F CB  1 
ATOM   11762 C  CG1 . VAL F 1 43  ? 32.107  26.176  39.884  1.00 29.85  ? 43  VAL F CG1 1 
ATOM   11763 C  CG2 . VAL F 1 43  ? 33.365  25.017  38.167  1.00 25.56  ? 43  VAL F CG2 1 
ATOM   11764 N  N   . ALA F 1 44  ? 29.360  26.265  37.985  1.00 22.91  ? 44  ALA F N   1 
ATOM   11765 C  CA  . ALA F 1 44  ? 28.103  25.563  37.742  1.00 22.39  ? 44  ALA F CA  1 
ATOM   11766 C  C   . ALA F 1 44  ? 27.589  25.881  36.337  1.00 26.99  ? 44  ALA F C   1 
ATOM   11767 O  O   . ALA F 1 44  ? 27.136  24.987  35.626  1.00 28.59  ? 44  ALA F O   1 
ATOM   11768 C  CB  . ALA F 1 44  ? 27.067  25.932  38.777  1.00 21.80  ? 44  ALA F CB  1 
ATOM   11769 N  N   . SER F 1 45  ? 27.679  27.144  35.889  1.00 26.83  ? 45  SER F N   1 
ATOM   11770 C  CA  . SER F 1 45  ? 27.104  27.431  34.580  1.00 28.77  ? 45  SER F CA  1 
ATOM   11771 C  C   . SER F 1 45  ? 27.972  26.867  33.462  1.00 25.46  ? 45  SER F C   1 
ATOM   11772 O  O   . SER F 1 45  ? 27.449  26.555  32.408  1.00 25.19  ? 45  SER F O   1 
ATOM   11773 C  CB  . SER F 1 45  ? 26.764  28.893  34.353  1.00 30.14  ? 45  SER F CB  1 
ATOM   11774 O  OG  . SER F 1 45  ? 27.835  29.737  34.728  1.00 35.19  ? 45  SER F OG  1 
ATOM   11775 N  N   . LEU F 1 46  ? 29.275  26.703  33.696  1.00 26.61  ? 46  LEU F N   1 
ATOM   11776 C  CA  . LEU F 1 46  ? 30.156  26.074  32.719  1.00 24.35  ? 46  LEU F CA  1 
ATOM   11777 C  C   . LEU F 1 46  ? 29.902  24.572  32.628  1.00 25.17  ? 46  LEU F C   1 
ATOM   11778 O  O   . LEU F 1 46  ? 30.023  24.005  31.547  1.00 28.79  ? 46  LEU F O   1 
ATOM   11779 C  CB  . LEU F 1 46  ? 31.591  26.389  33.100  1.00 23.04  ? 46  LEU F CB  1 
ATOM   11780 C  CG  . LEU F 1 46  ? 31.954  27.855  32.910  1.00 24.95  ? 46  LEU F CG  1 
ATOM   11781 C  CD1 . LEU F 1 46  ? 33.358  28.081  33.409  1.00 29.15  ? 46  LEU F CD1 1 
ATOM   11782 C  CD2 . LEU F 1 46  ? 31.850  28.331  31.470  1.00 29.17  ? 46  LEU F CD2 1 
ATOM   11783 N  N   . GLU F 1 47  ? 29.550  23.934  33.756  1.00 25.63  ? 47  GLU F N   1 
ATOM   11784 C  CA  . GLU F 1 47  ? 29.191  22.529  33.772  1.00 24.78  ? 47  GLU F CA  1 
ATOM   11785 C  C   . GLU F 1 47  ? 27.975  22.340  32.868  1.00 29.09  ? 47  GLU F C   1 
ATOM   11786 O  O   . GLU F 1 47  ? 27.912  21.390  32.078  1.00 27.67  ? 47  GLU F O   1 
ATOM   11787 C  CB  . GLU F 1 47  ? 28.953  22.170  35.223  1.00 25.05  ? 47  GLU F CB  1 
ATOM   11788 C  CG  . GLU F 1 47  ? 28.621  20.708  35.491  1.00 28.68  ? 47  GLU F CG  1 
ATOM   11789 C  CD  . GLU F 1 47  ? 28.636  20.380  36.981  1.00 33.19  ? 47  GLU F CD  1 
ATOM   11790 O  OE1 . GLU F 1 47  ? 28.994  21.220  37.824  1.00 45.70  ? 47  GLU F OE1 1 
ATOM   11791 O  OE2 . GLU F 1 47  ? 28.356  19.248  37.332  1.00 40.40  ? 47  GLU F OE2 1 
ATOM   11792 N  N   . ARG F 1 48  ? 27.018  23.275  32.937  1.00 27.21  ? 48  ARG F N   1 
ATOM   11793 C  CA  . ARG F 1 48  ? 25.846  23.146  32.093  1.00 26.53  ? 48  ARG F CA  1 
ATOM   11794 C  C   . ARG F 1 48  ? 26.154  23.475  30.648  1.00 25.30  ? 48  ARG F C   1 
ATOM   11795 O  O   . ARG F 1 48  ? 25.676  22.788  29.773  1.00 26.25  ? 48  ARG F O   1 
ATOM   11796 C  CB  . ARG F 1 48  ? 24.708  24.040  32.561  1.00 29.41  ? 48  ARG F CB  1 
ATOM   11797 C  CG  . ARG F 1 48  ? 24.260  23.546  33.917  1.00 30.57  ? 48  ARG F CG  1 
ATOM   11798 C  CD  . ARG F 1 48  ? 22.891  24.143  34.170  1.00 40.09  ? 48  ARG F CD  1 
ATOM   11799 N  NE  . ARG F 1 48  ? 22.909  25.607  34.326  1.00 42.60  ? 48  ARG F NE  1 
ATOM   11800 C  CZ  . ARG F 1 48  ? 23.319  26.270  35.397  1.00 37.37  ? 48  ARG F CZ  1 
ATOM   11801 N  NH1 . ARG F 1 48  ? 23.601  25.642  36.519  1.00 38.71  ? 48  ARG F NH1 1 
ATOM   11802 N  NH2 . ARG F 1 48  ? 23.469  27.566  35.330  1.00 36.19  ? 48  ARG F NH2 1 
ATOM   11803 N  N   . ALA F 1 49  ? 26.919  24.534  30.387  1.00 24.46  ? 49  ALA F N   1 
ATOM   11804 C  CA  . ALA F 1 49  ? 27.217  24.876  29.017  1.00 22.75  ? 49  ALA F CA  1 
ATOM   11805 C  C   . ALA F 1 49  ? 27.801  23.664  28.287  1.00 24.56  ? 49  ALA F C   1 
ATOM   11806 O  O   . ALA F 1 49  ? 27.349  23.317  27.198  1.00 30.43  ? 49  ALA F O   1 
ATOM   11807 C  CB  . ALA F 1 49  ? 28.158  26.010  28.985  1.00 25.41  ? 49  ALA F CB  1 
ATOM   11808 N  N   . VAL F 1 50  ? 28.777  23.001  28.903  1.00 21.65  ? 50  VAL F N   1 
ATOM   11809 C  CA  . VAL F 1 50  ? 29.460  21.896  28.260  1.00 24.18  ? 50  VAL F CA  1 
ATOM   11810 C  C   . VAL F 1 50  ? 28.610  20.620  28.295  1.00 26.88  ? 50  VAL F C   1 
ATOM   11811 O  O   . VAL F 1 50  ? 28.623  19.845  27.340  1.00 25.30  ? 50  VAL F O   1 
ATOM   11812 C  CB  . VAL F 1 50  ? 30.822  21.617  28.921  1.00 27.43  ? 50  VAL F CB  1 
ATOM   11813 C  CG1 . VAL F 1 50  ? 31.498  20.345  28.366  1.00 27.91  ? 50  VAL F CG1 1 
ATOM   11814 C  CG2 . VAL F 1 50  ? 31.730  22.847  28.870  1.00 26.44  ? 50  VAL F CG2 1 
ATOM   11815 N  N   . GLY F 1 51  ? 27.885  20.370  29.392  1.00 25.76  ? 51  GLY F N   1 
ATOM   11816 C  CA  . GLY F 1 51  ? 27.229  19.079  29.549  1.00 28.51  ? 51  GLY F CA  1 
ATOM   11817 C  C   . GLY F 1 51  ? 25.803  19.010  28.963  1.00 30.34  ? 51  GLY F C   1 
ATOM   11818 O  O   . GLY F 1 51  ? 25.310  17.957  28.563  1.00 26.81  ? 51  GLY F O   1 
ATOM   11819 N  N   . PHE F 1 52  ? 25.074  20.121  28.951  1.00 27.69  ? 52  PHE F N   1 
ATOM   11820 C  CA  . PHE F 1 52  ? 23.675  20.074  28.587  1.00 30.27  ? 52  PHE F CA  1 
ATOM   11821 C  C   . PHE F 1 52  ? 23.471  19.366  27.238  1.00 33.80  ? 52  PHE F C   1 
ATOM   11822 O  O   . PHE F 1 52  ? 22.653  18.444  27.122  1.00 33.32  ? 52  PHE F O   1 
ATOM   11823 C  CB  . PHE F 1 52  ? 23.092  21.491  28.605  1.00 32.50  ? 52  PHE F CB  1 
ATOM   11824 C  CG  . PHE F 1 52  ? 21.612  21.359  28.336  1.00 31.49  ? 52  PHE F CG  1 
ATOM   11825 C  CD1 . PHE F 1 52  ? 20.761  20.752  29.257  1.00 31.95  ? 52  PHE F CD1 1 
ATOM   11826 C  CD2 . PHE F 1 52  ? 21.111  21.698  27.106  1.00 31.99  ? 52  PHE F CD2 1 
ATOM   11827 C  CE1 . PHE F 1 52  ? 19.439  20.499  28.958  1.00 31.87  ? 52  PHE F CE1 1 
ATOM   11828 C  CE2 . PHE F 1 52  ? 19.779  21.473  26.833  1.00 32.92  ? 52  PHE F CE2 1 
ATOM   11829 C  CZ  . PHE F 1 52  ? 18.950  20.886  27.762  1.00 32.84  ? 52  PHE F CZ  1 
ATOM   11830 N  N   . ARG F 1 53  ? 24.231  19.783  26.218  1.00 35.92  ? 53  ARG F N   1 
ATOM   11831 C  CA  . ARG F 1 53  ? 24.043  19.293  24.857  1.00 35.28  ? 53  ARG F CA  1 
ATOM   11832 C  C   . ARG F 1 53  ? 24.310  17.788  24.740  1.00 34.31  ? 53  ARG F C   1 
ATOM   11833 O  O   . ARG F 1 53  ? 23.996  17.191  23.709  1.00 35.81  ? 53  ARG F O   1 
ATOM   11834 C  CB  . ARG F 1 53  ? 24.874  20.115  23.843  1.00 42.15  ? 53  ARG F CB  1 
ATOM   11835 C  CG  . ARG F 1 53  ? 26.387  19.936  23.772  1.00 46.10  ? 53  ARG F CG  1 
ATOM   11836 C  CD  . ARG F 1 53  ? 27.062  20.608  22.532  1.00 47.85  ? 53  ARG F CD  1 
ATOM   11837 N  NE  . ARG F 1 53  ? 28.363  21.203  22.862  1.00 43.10  ? 53  ARG F NE  1 
ATOM   11838 C  CZ  . ARG F 1 53  ? 28.427  22.043  23.909  1.00 54.73  ? 53  ARG F CZ  1 
ATOM   11839 N  NH1 . ARG F 1 53  ? 27.315  22.381  24.550  1.00 76.12  ? 53  ARG F NH1 1 
ATOM   11840 N  NH2 . ARG F 1 53  ? 29.559  22.561  24.354  1.00 53.49  ? 53  ARG F NH2 1 
ATOM   11841 N  N   . ALA F 1 54  ? 24.950  17.191  25.751  1.00 32.41  ? 54  ALA F N   1 
ATOM   11842 C  CA  . ALA F 1 54  ? 25.348  15.794  25.707  1.00 33.76  ? 54  ALA F CA  1 
ATOM   11843 C  C   . ALA F 1 54  ? 24.426  14.961  26.566  1.00 39.85  ? 54  ALA F C   1 
ATOM   11844 O  O   . ALA F 1 54  ? 24.749  13.803  26.806  1.00 51.63  ? 54  ALA F O   1 
ATOM   11845 C  CB  . ALA F 1 54  ? 26.758  15.594  26.203  1.00 31.72  ? 54  ALA F CB  1 
ATOM   11846 N  N   . GLN F 1 55  ? 23.302  15.536  26.999  1.00 41.85  ? 55  GLN F N   1 
ATOM   11847 C  CA  . GLN F 1 55  ? 22.310  14.756  27.719  1.00 55.39  ? 55  GLN F CA  1 
ATOM   11848 C  C   . GLN F 1 55  ? 21.671  13.692  26.822  1.00 67.12  ? 55  GLN F C   1 
ATOM   11849 O  O   . GLN F 1 55  ? 21.594  13.848  25.607  1.00 83.50  ? 55  GLN F O   1 
ATOM   11850 C  CB  . GLN F 1 55  ? 21.216  15.611  28.353  1.00 62.14  ? 55  GLN F CB  1 
ATOM   11851 C  CG  . GLN F 1 55  ? 21.688  16.441  29.546  1.00 68.98  ? 55  GLN F CG  1 
ATOM   11852 C  CD  . GLN F 1 55  ? 22.427  15.663  30.627  1.00 74.85  ? 55  GLN F CD  1 
ATOM   11853 O  OE1 . GLN F 1 55  ? 22.912  14.533  30.462  1.00 78.69  ? 55  GLN F OE1 1 
ATOM   11854 N  NE2 . GLN F 1 55  ? 22.570  16.311  31.769  1.00 69.67  ? 55  GLN F NE2 1 
ATOM   11855 N  N   . PRO F 1 56  ? 21.249  12.544  27.407  1.00 74.43  ? 56  PRO F N   1 
ATOM   11856 C  CA  . PRO F 1 56  ? 21.479  12.267  28.836  1.00 62.98  ? 56  PRO F CA  1 
ATOM   11857 C  C   . PRO F 1 56  ? 22.678  11.361  29.159  1.00 55.01  ? 56  PRO F C   1 
ATOM   11858 O  O   . PRO F 1 56  ? 23.074  11.294  30.308  1.00 53.01  ? 56  PRO F O   1 
ATOM   11859 C  CB  . PRO F 1 56  ? 20.118  11.680  29.219  1.00 54.87  ? 56  PRO F CB  1 
ATOM   11860 C  CG  . PRO F 1 56  ? 19.548  11.115  27.906  1.00 60.22  ? 56  PRO F CG  1 
ATOM   11861 C  CD  . PRO F 1 56  ? 20.493  11.466  26.748  1.00 63.30  ? 56  PRO F CD  1 
ATOM   11862 N  N   . ASP F 1 57  ? 23.323  10.783  28.132  1.00 57.73  ? 57  ASP F N   1 
ATOM   11863 C  CA  . ASP F 1 57  ? 24.431  9.849   28.295  1.00 60.56  ? 57  ASP F CA  1 
ATOM   11864 C  C   . ASP F 1 57  ? 25.657  10.466  28.959  1.00 55.21  ? 57  ASP F C   1 
ATOM   11865 O  O   . ASP F 1 57  ? 26.435  9.717   29.560  1.00 48.99  ? 57  ASP F O   1 
ATOM   11866 C  CB  . ASP F 1 57  ? 24.982  9.387   26.962  1.00 62.75  ? 57  ASP F CB  1 
ATOM   11867 C  CG  . ASP F 1 57  ? 23.876  9.174   25.963  1.00 69.59  ? 57  ASP F CG  1 
ATOM   11868 O  OD1 . ASP F 1 57  ? 22.967  8.414   26.325  1.00 64.28  ? 57  ASP F OD1 1 
ATOM   11869 O  OD2 . ASP F 1 57  ? 23.899  9.855   24.917  1.00 82.09  ? 57  ASP F OD2 1 
ATOM   11870 N  N   . GLY F 1 58  ? 25.836  11.796  28.834  1.00 44.95  ? 58  GLY F N   1 
ATOM   11871 C  CA  . GLY F 1 58  ? 27.082  12.472  29.185  1.00 38.60  ? 58  GLY F CA  1 
ATOM   11872 C  C   . GLY F 1 58  ? 27.449  12.331  30.663  1.00 36.90  ? 58  GLY F C   1 
ATOM   11873 O  O   . GLY F 1 58  ? 28.586  11.964  30.986  1.00 32.03  ? 58  GLY F O   1 
ATOM   11874 N  N   . ARG F 1 59  ? 26.490  12.652  31.551  1.00 35.24  ? 59  ARG F N   1 
ATOM   11875 C  CA  . ARG F 1 59  ? 26.665  12.498  32.986  1.00 36.88  ? 59  ARG F CA  1 
ATOM   11876 C  C   . ARG F 1 59  ? 27.887  13.305  33.465  1.00 34.97  ? 59  ARG F C   1 
ATOM   11877 O  O   . ARG F 1 59  ? 28.583  12.899  34.410  1.00 35.73  ? 59  ARG F O   1 
ATOM   11878 C  CB  . ARG F 1 59  ? 26.740  10.996  33.340  1.00 42.74  ? 59  ARG F CB  1 
ATOM   11879 C  CG  . ARG F 1 59  ? 25.413  10.243  33.272  1.00 48.00  ? 59  ARG F CG  1 
ATOM   11880 C  CD  . ARG F 1 59  ? 25.520  8.790   32.732  1.00 53.77  ? 59  ARG F CD  1 
ATOM   11881 N  NE  . ARG F 1 59  ? 25.369  7.742   33.746  1.00 48.27  ? 59  ARG F NE  1 
ATOM   11882 N  N   . LEU F 1 60  ? 28.128  14.472  32.852  1.00 25.06  ? 60  LEU F N   1 
ATOM   11883 C  CA  . LEU F 1 60  ? 29.240  15.338  33.225  1.00 24.22  ? 60  LEU F CA  1 
ATOM   11884 C  C   . LEU F 1 60  ? 28.928  16.023  34.547  1.00 24.61  ? 60  LEU F C   1 
ATOM   11885 O  O   . LEU F 1 60  ? 27.851  16.570  34.709  1.00 25.36  ? 60  LEU F O   1 
ATOM   11886 C  CB  . LEU F 1 60  ? 29.462  16.393  32.148  1.00 24.63  ? 60  LEU F CB  1 
ATOM   11887 C  CG  . LEU F 1 60  ? 30.578  17.407  32.389  1.00 24.17  ? 60  LEU F CG  1 
ATOM   11888 C  CD1 . LEU F 1 60  ? 31.942  16.791  32.272  1.00 25.90  ? 60  LEU F CD1 1 
ATOM   11889 C  CD2 . LEU F 1 60  ? 30.465  18.454  31.342  1.00 25.71  ? 60  LEU F CD2 1 
ATOM   11890 N  N   . SER F 1 61  ? 29.871  15.995  35.486  1.00 22.87  ? 61  SER F N   1 
ATOM   11891 C  CA  . SER F 1 61  ? 29.703  16.659  36.765  1.00 23.31  ? 61  SER F CA  1 
ATOM   11892 C  C   . SER F 1 61  ? 31.072  17.202  37.151  1.00 23.23  ? 61  SER F C   1 
ATOM   11893 O  O   . SER F 1 61  ? 32.097  16.593  36.800  1.00 22.64  ? 61  SER F O   1 
ATOM   11894 C  CB  . SER F 1 61  ? 29.138  15.732  37.821  1.00 23.81  ? 61  SER F CB  1 
ATOM   11895 O  OG  . SER F 1 61  ? 30.129  14.930  38.466  1.00 29.92  ? 61  SER F OG  1 
ATOM   11896 N  N   . CYS F 1 62  ? 31.092  18.375  37.781  1.00 23.05  ? 62  CYS F N   1 
ATOM   11897 C  CA  . CYS F 1 62  ? 32.335  18.916  38.312  1.00 25.88  ? 62  CYS F CA  1 
ATOM   11898 C  C   . CYS F 1 62  ? 32.199  19.165  39.806  1.00 24.47  ? 62  CYS F C   1 
ATOM   11899 O  O   . CYS F 1 62  ? 31.274  19.841  40.219  1.00 26.66  ? 62  CYS F O   1 
ATOM   11900 C  CB  . CYS F 1 62  ? 32.701  20.246  37.676  1.00 26.62  ? 62  CYS F CB  1 
ATOM   11901 S  SG  . CYS F 1 62  ? 34.281  20.809  38.327  1.00 29.78  ? 62  CYS F SG  1 
ATOM   11902 N  N   . VAL F 1 63  ? 33.079  18.612  40.628  1.00 23.58  ? 63  VAL F N   1 
ATOM   11903 C  CA  . VAL F 1 63  ? 33.037  18.924  42.051  1.00 22.17  ? 63  VAL F CA  1 
ATOM   11904 C  C   . VAL F 1 63  ? 34.281  19.754  42.351  1.00 22.89  ? 63  VAL F C   1 
ATOM   11905 O  O   . VAL F 1 63  ? 35.381  19.393  41.968  1.00 22.66  ? 63  VAL F O   1 
ATOM   11906 C  CB  . VAL F 1 63  ? 32.977  17.687  42.966  1.00 21.67  ? 63  VAL F CB  1 
ATOM   11907 C  CG1 . VAL F 1 63  ? 33.027  18.040  44.443  1.00 23.88  ? 63  VAL F CG1 1 
ATOM   11908 C  CG2 . VAL F 1 63  ? 31.757  16.835  42.670  1.00 22.14  ? 63  VAL F CG2 1 
ATOM   11909 N  N   . THR F 1 64  ? 34.074  20.900  43.003  1.00 23.37  ? 64  THR F N   1 
ATOM   11910 C  CA  . THR F 1 64  ? 35.113  21.892  43.203  1.00 21.85  ? 64  THR F CA  1 
ATOM   11911 C  C   . THR F 1 64  ? 35.415  21.882  44.677  1.00 21.90  ? 64  THR F C   1 
ATOM   11912 O  O   . THR F 1 64  ? 34.498  22.026  45.459  1.00 23.06  ? 64  THR F O   1 
ATOM   11913 C  CB  . THR F 1 64  ? 34.608  23.275  42.835  1.00 22.89  ? 64  THR F CB  1 
ATOM   11914 O  OG1 . THR F 1 64  ? 34.245  23.301  41.473  1.00 20.96  ? 64  THR F OG1 1 
ATOM   11915 C  CG2 . THR F 1 64  ? 35.689  24.316  42.971  1.00 25.77  ? 64  THR F CG2 1 
ATOM   11916 N  N   . GLY F 1 65  ? 36.683  21.703  45.023  1.00 24.82  ? 65  GLY F N   1 
ATOM   11917 C  CA  . GLY F 1 65  ? 37.119  21.603  46.407  1.00 25.23  ? 65  GLY F CA  1 
ATOM   11918 C  C   . GLY F 1 65  ? 38.123  22.701  46.710  1.00 23.87  ? 65  GLY F C   1 
ATOM   11919 O  O   . GLY F 1 65  ? 38.915  23.075  45.841  1.00 23.55  ? 65  GLY F O   1 
ATOM   11920 N  N   . ILE F 1 66  ? 38.097  23.199  47.948  1.00 24.02  ? 66  ILE F N   1 
ATOM   11921 C  CA  . ILE F 1 66  ? 39.006  24.269  48.347  1.00 25.79  ? 66  ILE F CA  1 
ATOM   11922 C  C   . ILE F 1 66  ? 39.811  23.811  49.551  1.00 23.13  ? 66  ILE F C   1 
ATOM   11923 O  O   . ILE F 1 66  ? 39.259  23.242  50.477  1.00 27.00  ? 66  ILE F O   1 
ATOM   11924 C  CB  . ILE F 1 66  ? 38.202  25.551  48.620  1.00 25.13  ? 66  ILE F CB  1 
ATOM   11925 C  CG1 . ILE F 1 66  ? 37.349  25.876  47.425  1.00 27.98  ? 66  ILE F CG1 1 
ATOM   11926 C  CG2 . ILE F 1 66  ? 39.120  26.711  48.984  1.00 25.19  ? 66  ILE F CG2 1 
ATOM   11927 C  CD1 . ILE F 1 66  ? 36.157  26.750  47.717  1.00 28.05  ? 66  ILE F CD1 1 
ATOM   11928 N  N   . GLY F 1 67  ? 41.111  24.064  49.499  1.00 24.07  ? 67  GLY F N   1 
ATOM   11929 C  CA  . GLY F 1 67  ? 42.035  23.710  50.570  1.00 30.35  ? 67  GLY F CA  1 
ATOM   11930 C  C   . GLY F 1 67  ? 41.988  24.672  51.772  1.00 32.22  ? 67  GLY F C   1 
ATOM   11931 O  O   . GLY F 1 67  ? 41.339  25.733  51.783  1.00 30.37  ? 67  GLY F O   1 
ATOM   11932 N  N   . SER F 1 68  ? 42.710  24.266  52.813  1.00 31.27  ? 68  SER F N   1 
ATOM   11933 C  CA  . SER F 1 68  ? 42.723  24.997  54.066  1.00 31.41  ? 68  SER F CA  1 
ATOM   11934 C  C   . SER F 1 68  ? 43.306  26.408  53.890  1.00 28.12  ? 68  SER F C   1 
ATOM   11935 O  O   . SER F 1 68  ? 42.633  27.389  54.199  1.00 26.35  ? 68  SER F O   1 
ATOM   11936 C  CB  . SER F 1 68  ? 43.444  24.177  55.134  1.00 32.33  ? 68  SER F CB  1 
ATOM   11937 O  OG  . SER F 1 68  ? 43.123  24.667  56.420  1.00 31.61  ? 68  SER F OG  1 
ATOM   11938 N  N   . GLU F 1 69  ? 44.526  26.527  53.366  1.00 26.75  ? 69  GLU F N   1 
ATOM   11939 C  CA  . GLU F 1 69  ? 45.127  27.846  53.267  1.00 31.07  ? 69  GLU F CA  1 
ATOM   11940 C  C   . GLU F 1 69  ? 44.475  28.716  52.190  1.00 33.47  ? 69  GLU F C   1 
ATOM   11941 O  O   . GLU F 1 69  ? 44.437  29.956  52.296  1.00 34.81  ? 69  GLU F O   1 
ATOM   11942 C  CB  . GLU F 1 69  ? 46.602  27.674  52.959  1.00 35.20  ? 69  GLU F CB  1 
ATOM   11943 C  CG  . GLU F 1 69  ? 47.364  26.978  54.092  1.00 49.96  ? 69  GLU F CG  1 
ATOM   11944 C  CD  . GLU F 1 69  ? 48.849  26.722  53.795  1.00 50.27  ? 69  GLU F CD  1 
ATOM   11945 O  OE1 . GLU F 1 69  ? 49.344  25.611  54.063  1.00 52.94  ? 69  GLU F OE1 1 
ATOM   11946 O  OE2 . GLU F 1 69  ? 49.484  27.626  53.208  1.00 48.14  ? 69  GLU F OE2 1 
ATOM   11947 N  N   . ALA F 1 70  ? 43.974  28.083  51.125  1.00 28.87  ? 70  ALA F N   1 
ATOM   11948 C  CA  . ALA F 1 70  ? 43.242  28.820  50.111  1.00 26.75  ? 70  ALA F CA  1 
ATOM   11949 C  C   . ALA F 1 70  ? 41.973  29.433  50.690  1.00 24.48  ? 70  ALA F C   1 
ATOM   11950 O  O   . ALA F 1 70  ? 41.602  30.552  50.347  1.00 23.95  ? 70  ALA F O   1 
ATOM   11951 C  CB  . ALA F 1 70  ? 42.928  27.887  48.970  1.00 29.39  ? 70  ALA F CB  1 
ATOM   11952 N  N   . TRP F 1 71  ? 41.300  28.668  51.556  1.00 23.75  ? 71  TRP F N   1 
ATOM   11953 C  CA  . TRP F 1 71  ? 40.068  29.118  52.178  1.00 26.41  ? 71  TRP F CA  1 
ATOM   11954 C  C   . TRP F 1 71  ? 40.259  30.508  52.806  1.00 27.23  ? 71  TRP F C   1 
ATOM   11955 O  O   . TRP F 1 71  ? 39.447  31.416  52.635  1.00 28.04  ? 71  TRP F O   1 
ATOM   11956 C  CB  . TRP F 1 71  ? 39.572  28.098  53.234  1.00 27.95  ? 71  TRP F CB  1 
ATOM   11957 C  CG  . TRP F 1 71  ? 38.164  28.435  53.640  1.00 29.74  ? 71  TRP F CG  1 
ATOM   11958 C  CD1 . TRP F 1 71  ? 37.800  29.421  54.510  1.00 32.27  ? 71  TRP F CD1 1 
ATOM   11959 C  CD2 . TRP F 1 71  ? 36.939  27.950  53.051  1.00 33.51  ? 71  TRP F CD2 1 
ATOM   11960 N  NE1 . TRP F 1 71  ? 36.441  29.559  54.542  1.00 32.57  ? 71  TRP F NE1 1 
ATOM   11961 C  CE2 . TRP F 1 71  ? 35.888  28.677  53.654  1.00 34.51  ? 71  TRP F CE2 1 
ATOM   11962 C  CE3 . TRP F 1 71  ? 36.628  26.964  52.107  1.00 36.66  ? 71  TRP F CE3 1 
ATOM   11963 C  CZ2 . TRP F 1 71  ? 34.560  28.435  53.350  1.00 34.67  ? 71  TRP F CZ2 1 
ATOM   11964 C  CZ3 . TRP F 1 71  ? 35.313  26.755  51.782  1.00 34.68  ? 71  TRP F CZ3 1 
ATOM   11965 C  CH2 . TRP F 1 71  ? 34.308  27.497  52.380  1.00 36.42  ? 71  TRP F CH2 1 
ATOM   11966 N  N   . ASP F 1 72  ? 41.359  30.634  53.549  1.00 32.35  ? 72  ASP F N   1 
ATOM   11967 C  CA  . ASP F 1 72  ? 41.748  31.808  54.299  1.00 32.39  ? 72  ASP F CA  1 
ATOM   11968 C  C   . ASP F 1 72  ? 42.046  32.977  53.382  1.00 31.91  ? 72  ASP F C   1 
ATOM   11969 O  O   . ASP F 1 72  ? 41.743  34.121  53.731  1.00 31.64  ? 72  ASP F O   1 
ATOM   11970 C  CB  . ASP F 1 72  ? 42.953  31.457  55.147  1.00 30.80  ? 72  ASP F CB  1 
ATOM   11971 C  CG  . ASP F 1 72  ? 42.578  30.609  56.349  1.00 31.31  ? 72  ASP F CG  1 
ATOM   11972 O  OD1 . ASP F 1 72  ? 41.344  30.621  56.690  1.00 32.50  ? 72  ASP F OD1 1 
ATOM   11973 O  OD2 . ASP F 1 72  ? 43.517  29.976  56.903  1.00 31.75  ? 72  ASP F OD2 1 
ATOM   11974 N  N   . ARG F 1 73  ? 42.652  32.687  52.230  1.00 28.94  ? 73  ARG F N   1 
ATOM   11975 C  CA  . ARG F 1 73  ? 42.914  33.774  51.297  1.00 30.87  ? 73  ARG F CA  1 
ATOM   11976 C  C   . ARG F 1 73  ? 41.652  34.235  50.567  1.00 31.30  ? 73  ARG F C   1 
ATOM   11977 O  O   . ARG F 1 73  ? 41.622  35.342  50.069  1.00 35.09  ? 73  ARG F O   1 
ATOM   11978 C  CB  . ARG F 1 73  ? 43.958  33.414  50.240  1.00 32.02  ? 73  ARG F CB  1 
ATOM   11979 C  CG  . ARG F 1 73  ? 45.234  32.919  50.896  1.00 33.60  ? 73  ARG F CG  1 
ATOM   11980 C  CD  . ARG F 1 73  ? 46.130  32.117  49.966  1.00 33.20  ? 73  ARG F CD  1 
ATOM   11981 N  NE  . ARG F 1 73  ? 46.472  32.842  48.742  1.00 28.82  ? 73  ARG F NE  1 
ATOM   11982 C  CZ  . ARG F 1 73  ? 47.099  32.281  47.700  1.00 30.29  ? 73  ARG F CZ  1 
ATOM   11983 N  NH1 . ARG F 1 73  ? 47.372  30.972  47.706  1.00 33.40  ? 73  ARG F NH1 1 
ATOM   11984 N  NH2 . ARG F 1 73  ? 47.435  33.021  46.641  1.00 32.20  ? 73  ARG F NH2 1 
ATOM   11985 N  N   . LEU F 1 74  ? 40.623  33.392  50.447  1.00 32.12  ? 74  LEU F N   1 
ATOM   11986 C  CA  . LEU F 1 74  ? 39.563  33.670  49.494  1.00 30.20  ? 74  LEU F CA  1 
ATOM   11987 C  C   . LEU F 1 74  ? 38.336  34.251  50.175  1.00 28.58  ? 74  LEU F C   1 
ATOM   11988 O  O   . LEU F 1 74  ? 37.611  34.970  49.510  1.00 28.43  ? 74  LEU F O   1 
ATOM   11989 C  CB  . LEU F 1 74  ? 39.159  32.412  48.737  1.00 32.50  ? 74  LEU F CB  1 
ATOM   11990 C  CG  . LEU F 1 74  ? 40.109  31.913  47.646  1.00 33.30  ? 74  LEU F CG  1 
ATOM   11991 C  CD1 . LEU F 1 74  ? 39.685  30.531  47.154  1.00 35.11  ? 74  LEU F CD1 1 
ATOM   11992 C  CD2 . LEU F 1 74  ? 40.122  32.888  46.499  1.00 33.53  ? 74  LEU F CD2 1 
ATOM   11993 N  N   . PHE F 1 75  ? 38.066  33.874  51.430  1.00 31.68  ? 75  PHE F N   1 
ATOM   11994 C  CA  . PHE F 1 75  ? 36.747  34.101  51.995  1.00 35.55  ? 75  PHE F CA  1 
ATOM   11995 C  C   . PHE F 1 75  ? 36.726  34.905  53.291  1.00 42.44  ? 75  PHE F C   1 
ATOM   11996 O  O   . PHE F 1 75  ? 37.558  34.680  54.164  1.00 39.52  ? 75  PHE F O   1 
ATOM   11997 C  CB  . PHE F 1 75  ? 36.119  32.742  52.245  1.00 33.78  ? 75  PHE F CB  1 
ATOM   11998 C  CG  . PHE F 1 75  ? 35.896  32.008  50.947  1.00 35.02  ? 75  PHE F CG  1 
ATOM   11999 C  CD1 . PHE F 1 75  ? 35.268  32.634  49.859  1.00 35.35  ? 75  PHE F CD1 1 
ATOM   12000 C  CD2 . PHE F 1 75  ? 36.352  30.701  50.825  1.00 36.93  ? 75  PHE F CD2 1 
ATOM   12001 C  CE1 . PHE F 1 75  ? 35.089  31.957  48.663  1.00 37.96  ? 75  PHE F CE1 1 
ATOM   12002 C  CE2 . PHE F 1 75  ? 36.181  30.026  49.627  1.00 41.09  ? 75  PHE F CE2 1 
ATOM   12003 C  CZ  . PHE F 1 75  ? 35.569  30.667  48.538  1.00 39.33  ? 75  PHE F CZ  1 
ATOM   12004 N  N   . SER F 1 76  ? 35.684  35.775  53.366  1.00 56.63  ? 76  SER F N   1 
ATOM   12005 C  CA  . SER F 1 76  ? 35.364  36.687  54.462  1.00 54.16  ? 76  SER F CA  1 
ATOM   12006 C  C   . SER F 1 76  ? 35.416  35.980  55.834  1.00 52.73  ? 76  SER F C   1 
ATOM   12007 O  O   . SER F 1 76  ? 36.341  36.206  56.599  1.00 52.57  ? 76  SER F O   1 
ATOM   12008 C  CB  . SER F 1 76  ? 34.026  37.402  54.189  1.00 41.09  ? 76  SER F CB  1 
ATOM   12009 N  N   . GLY F 1 77  ? 34.468  35.105  56.179  1.00 43.62  ? 77  GLY F N   1 
ATOM   12010 C  CA  . GLY F 1 77  ? 34.248  34.823  57.593  1.00 38.49  ? 77  GLY F CA  1 
ATOM   12011 C  C   . GLY F 1 77  ? 34.557  33.387  58.009  1.00 38.72  ? 77  GLY F C   1 
ATOM   12012 O  O   . GLY F 1 77  ? 35.699  32.981  57.900  1.00 35.73  ? 77  GLY F O   1 
ATOM   12013 N  N   . ALA F 1 78  ? 33.541  32.660  58.525  1.00 40.90  ? 78  ALA F N   1 
ATOM   12014 C  CA  . ALA F 1 78  ? 33.694  31.358  59.177  1.00 42.17  ? 78  ALA F CA  1 
ATOM   12015 C  C   . ALA F 1 78  ? 34.357  30.320  58.262  1.00 43.93  ? 78  ALA F C   1 
ATOM   12016 O  O   . ALA F 1 78  ? 34.201  30.362  57.036  1.00 40.73  ? 78  ALA F O   1 
ATOM   12017 C  CB  . ALA F 1 78  ? 32.340  30.867  59.656  1.00 44.06  ? 78  ALA F CB  1 
ATOM   12018 N  N   . ARG F 1 79  ? 35.145  29.433  58.897  1.00 41.39  ? 79  ARG F N   1 
ATOM   12019 C  CA  . ARG F 1 79  ? 35.736  28.267  58.274  1.00 35.62  ? 79  ARG F CA  1 
ATOM   12020 C  C   . ARG F 1 79  ? 34.904  27.014  58.549  1.00 37.66  ? 79  ARG F C   1 
ATOM   12021 O  O   . ARG F 1 79  ? 34.364  26.849  59.631  1.00 33.60  ? 79  ARG F O   1 
ATOM   12022 C  CB  . ARG F 1 79  ? 37.119  28.064  58.882  1.00 35.67  ? 79  ARG F CB  1 
ATOM   12023 C  CG  . ARG F 1 79  ? 38.118  29.067  58.342  1.00 35.48  ? 79  ARG F CG  1 
ATOM   12024 C  CD  . ARG F 1 79  ? 39.465  28.869  58.974  1.00 32.56  ? 79  ARG F CD  1 
ATOM   12025 N  NE  . ARG F 1 79  ? 39.863  27.466  58.881  1.00 37.69  ? 79  ARG F NE  1 
ATOM   12026 C  CZ  . ARG F 1 79  ? 40.705  26.940  58.003  1.00 42.61  ? 79  ARG F CZ  1 
ATOM   12027 N  NH1 . ARG F 1 79  ? 41.258  27.727  57.089  1.00 45.84  ? 79  ARG F NH1 1 
ATOM   12028 N  NH2 . ARG F 1 79  ? 40.990  25.638  58.028  1.00 36.36  ? 79  ARG F NH2 1 
ATOM   12029 N  N   . PRO F 1 80  ? 34.770  26.066  57.595  1.00 36.52  ? 80  PRO F N   1 
ATOM   12030 C  CA  . PRO F 1 80  ? 34.231  24.754  57.931  1.00 38.04  ? 80  PRO F CA  1 
ATOM   12031 C  C   . PRO F 1 80  ? 35.037  24.185  59.091  1.00 34.16  ? 80  PRO F C   1 
ATOM   12032 O  O   . PRO F 1 80  ? 36.258  24.293  59.108  1.00 31.09  ? 80  PRO F O   1 
ATOM   12033 C  CB  . PRO F 1 80  ? 34.426  23.965  56.622  1.00 40.37  ? 80  PRO F CB  1 
ATOM   12034 C  CG  . PRO F 1 80  ? 34.371  25.043  55.555  1.00 40.97  ? 80  PRO F CG  1 
ATOM   12035 C  CD  . PRO F 1 80  ? 35.101  26.202  56.172  1.00 35.68  ? 80  PRO F CD  1 
ATOM   12036 N  N   . ALA F 1 81  ? 34.327  23.569  60.035  1.00 34.07  ? 81  ALA F N   1 
ATOM   12037 C  CA  . ALA F 1 81  ? 34.916  23.013  61.246  1.00 31.65  ? 81  ALA F CA  1 
ATOM   12038 C  C   . ALA F 1 81  ? 36.098  22.081  60.996  1.00 30.41  ? 81  ALA F C   1 
ATOM   12039 O  O   . ALA F 1 81  ? 37.060  22.113  61.743  1.00 34.14  ? 81  ALA F O   1 
ATOM   12040 C  CB  . ALA F 1 81  ? 33.839  22.262  61.972  1.00 35.84  ? 81  ALA F CB  1 
ATOM   12041 N  N   . GLY F 1 82  ? 36.033  21.209  59.994  1.00 33.78  ? 82  GLY F N   1 
ATOM   12042 C  CA  . GLY F 1 82  ? 37.005  20.126  59.846  1.00 33.98  ? 82  GLY F CA  1 
ATOM   12043 C  C   . GLY F 1 82  ? 38.200  20.488  58.952  1.00 35.98  ? 82  GLY F C   1 
ATOM   12044 O  O   . GLY F 1 82  ? 39.089  19.674  58.720  1.00 35.28  ? 82  GLY F O   1 
ATOM   12045 N  N   . LEU F 1 83  ? 38.245  21.718  58.434  1.00 34.37  ? 83  LEU F N   1 
ATOM   12046 C  CA  . LEU F 1 83  ? 39.218  22.032  57.403  1.00 33.11  ? 83  LEU F CA  1 
ATOM   12047 C  C   . LEU F 1 83  ? 40.584  22.358  58.005  1.00 33.36  ? 83  LEU F C   1 
ATOM   12048 O  O   . LEU F 1 83  ? 40.770  23.331  58.715  1.00 37.33  ? 83  LEU F O   1 
ATOM   12049 C  CB  . LEU F 1 83  ? 38.678  23.175  56.542  1.00 32.09  ? 83  LEU F CB  1 
ATOM   12050 C  CG  . LEU F 1 83  ? 39.470  23.478  55.266  1.00 29.29  ? 83  LEU F CG  1 
ATOM   12051 C  CD1 . LEU F 1 83  ? 39.679  22.283  54.326  1.00 27.14  ? 83  LEU F CD1 1 
ATOM   12052 C  CD2 . LEU F 1 83  ? 38.746  24.621  54.553  1.00 33.72  ? 83  LEU F CD2 1 
ATOM   12053 N  N   . HIS F 1 84  ? 41.583  21.579  57.635  1.00 32.94  ? 84  HIS F N   1 
ATOM   12054 C  CA  . HIS F 1 84  ? 42.960  21.864  57.975  1.00 30.26  ? 84  HIS F CA  1 
ATOM   12055 C  C   . HIS F 1 84  ? 43.821  21.352  56.837  1.00 31.45  ? 84  HIS F C   1 
ATOM   12056 O  O   . HIS F 1 84  ? 43.313  20.667  55.967  1.00 37.95  ? 84  HIS F O   1 
ATOM   12057 C  CB  . HIS F 1 84  ? 43.332  21.117  59.259  1.00 27.44  ? 84  HIS F CB  1 
ATOM   12058 C  CG  . HIS F 1 84  ? 42.831  19.716  59.331  1.00 25.99  ? 84  HIS F CG  1 
ATOM   12059 N  ND1 . HIS F 1 84  ? 41.614  19.397  59.889  1.00 29.29  ? 84  HIS F ND1 1 
ATOM   12060 C  CD2 . HIS F 1 84  ? 43.372  18.545  58.938  1.00 25.84  ? 84  HIS F CD2 1 
ATOM   12061 C  CE1 . HIS F 1 84  ? 41.443  18.070  59.850  1.00 27.36  ? 84  HIS F CE1 1 
ATOM   12062 N  NE2 . HIS F 1 84  ? 42.502  17.539  59.270  1.00 25.74  ? 84  HIS F NE2 1 
ATOM   12063 N  N   . PRO F 1 85  ? 45.137  21.620  56.801  1.00 35.03  ? 85  PRO F N   1 
ATOM   12064 C  CA  . PRO F 1 85  ? 46.035  20.972  55.835  1.00 31.74  ? 85  PRO F CA  1 
ATOM   12065 C  C   . PRO F 1 85  ? 46.083  19.479  56.060  1.00 28.79  ? 85  PRO F C   1 
ATOM   12066 O  O   . PRO F 1 85  ? 45.850  19.040  57.165  1.00 29.84  ? 85  PRO F O   1 
ATOM   12067 C  CB  . PRO F 1 85  ? 47.405  21.637  56.102  1.00 34.00  ? 85  PRO F CB  1 
ATOM   12068 C  CG  . PRO F 1 85  ? 47.006  23.007  56.674  1.00 33.93  ? 85  PRO F CG  1 
ATOM   12069 C  CD  . PRO F 1 85  ? 45.827  22.649  57.593  1.00 34.43  ? 85  PRO F CD  1 
ATOM   12070 N  N   . PHE F 1 86  ? 46.299  18.705  54.997  1.00 29.35  ? 86  PHE F N   1 
ATOM   12071 C  CA  . PHE F 1 86  ? 46.475  17.275  55.135  1.00 27.44  ? 86  PHE F CA  1 
ATOM   12072 C  C   . PHE F 1 86  ? 47.694  17.019  56.023  1.00 28.09  ? 86  PHE F C   1 
ATOM   12073 O  O   . PHE F 1 86  ? 48.749  17.599  55.828  1.00 29.13  ? 86  PHE F O   1 
ATOM   12074 C  CB  . PHE F 1 86  ? 46.596  16.705  53.723  1.00 27.67  ? 86  PHE F CB  1 
ATOM   12075 C  CG  . PHE F 1 86  ? 46.940  15.222  53.643  1.00 30.28  ? 86  PHE F CG  1 
ATOM   12076 C  CD1 . PHE F 1 86  ? 48.224  14.739  53.902  1.00 28.34  ? 86  PHE F CD1 1 
ATOM   12077 C  CD2 . PHE F 1 86  ? 45.958  14.301  53.296  1.00 31.49  ? 86  PHE F CD2 1 
ATOM   12078 C  CE1 . PHE F 1 86  ? 48.497  13.381  53.814  1.00 30.74  ? 86  PHE F CE1 1 
ATOM   12079 C  CE2 . PHE F 1 86  ? 46.254  12.947  53.172  1.00 30.38  ? 86  PHE F CE2 1 
ATOM   12080 C  CZ  . PHE F 1 86  ? 47.515  12.488  53.448  1.00 30.89  ? 86  PHE F CZ  1 
ATOM   12081 N  N   . ARG F 1 87  ? 47.523  16.132  56.995  1.00 32.41  ? 87  ARG F N   1 
ATOM   12082 C  CA  . ARG F 1 87  ? 48.553  15.789  57.942  1.00 38.15  ? 87  ARG F CA  1 
ATOM   12083 C  C   . ARG F 1 87  ? 49.404  14.645  57.412  1.00 32.76  ? 87  ARG F C   1 
ATOM   12084 O  O   . ARG F 1 87  ? 48.926  13.527  57.213  1.00 31.84  ? 87  ARG F O   1 
ATOM   12085 C  CB  . ARG F 1 87  ? 47.873  15.303  59.218  1.00 46.94  ? 87  ARG F CB  1 
ATOM   12086 C  CG  . ARG F 1 87  ? 46.957  16.366  59.778  1.00 54.04  ? 87  ARG F CG  1 
ATOM   12087 C  CD  . ARG F 1 87  ? 46.482  15.817  61.086  1.00 63.47  ? 87  ARG F CD  1 
ATOM   12088 N  NE  . ARG F 1 87  ? 45.986  17.043  61.702  1.00 67.00  ? 87  ARG F NE  1 
ATOM   12089 C  CZ  . ARG F 1 87  ? 44.728  17.255  62.002  1.00 75.45  ? 87  ARG F CZ  1 
ATOM   12090 N  NH1 . ARG F 1 87  ? 43.844  16.254  61.976  1.00 94.48  ? 87  ARG F NH1 1 
ATOM   12091 N  NH2 . ARG F 1 87  ? 44.397  18.477  62.365  1.00 67.84  ? 87  ARG F NH2 1 
ATOM   12092 N  N   . GLU F 1 88  ? 50.691  14.943  57.262  1.00 33.44  ? 88  GLU F N   1 
ATOM   12093 C  CA  . GLU F 1 88  ? 51.688  13.966  56.888  1.00 35.59  ? 88  GLU F CA  1 
ATOM   12094 C  C   . GLU F 1 88  ? 51.553  12.803  57.855  1.00 32.85  ? 88  GLU F C   1 
ATOM   12095 O  O   . GLU F 1 88  ? 51.137  13.036  58.970  1.00 35.17  ? 88  GLU F O   1 
ATOM   12096 C  CB  . GLU F 1 88  ? 52.998  14.755  56.878  1.00 46.62  ? 88  GLU F CB  1 
ATOM   12097 C  CG  . GLU F 1 88  ? 54.153  14.010  56.193  1.00 63.62  ? 88  GLU F CG  1 
ATOM   12098 C  CD  . GLU F 1 88  ? 55.103  14.790  55.279  1.00 68.02  ? 88  GLU F CD  1 
ATOM   12099 O  OE1 . GLU F 1 88  ? 54.697  15.311  54.160  1.00 49.17  ? 88  GLU F OE1 1 
ATOM   12100 O  OE2 . GLU F 1 88  ? 56.302  14.795  55.705  1.00 78.31  ? 88  GLU F OE2 1 
ATOM   12101 N  N   . LEU F 1 89  ? 51.799  11.560  57.428  1.00 36.00  ? 89  LEU F N   1 
ATOM   12102 C  CA  . LEU F 1 89  ? 51.844  10.422  58.355  1.00 37.25  ? 89  LEU F CA  1 
ATOM   12103 C  C   . LEU F 1 89  ? 53.185  9.727   58.185  1.00 37.71  ? 89  LEU F C   1 
ATOM   12104 O  O   . LEU F 1 89  ? 53.535  9.303   57.080  1.00 37.37  ? 89  LEU F O   1 
ATOM   12105 C  CB  . LEU F 1 89  ? 50.727  9.379   58.234  1.00 38.74  ? 89  LEU F CB  1 
ATOM   12106 C  CG  . LEU F 1 89  ? 49.297  9.891   58.396  1.00 37.98  ? 89  LEU F CG  1 
ATOM   12107 C  CD1 . LEU F 1 89  ? 48.378  8.686   58.291  1.00 44.08  ? 89  LEU F CD1 1 
ATOM   12108 C  CD2 . LEU F 1 89  ? 49.064  10.645  59.671  1.00 33.25  ? 89  LEU F CD2 1 
ATOM   12109 N  N   . ASP F 1 90  ? 53.935  9.649   59.294  1.00 45.47  ? 90  ASP F N   1 
ATOM   12110 C  CA  . ASP F 1 90  ? 55.327  9.256   59.226  1.00 44.91  ? 90  ASP F CA  1 
ATOM   12111 C  C   . ASP F 1 90  ? 55.438  7.907   59.892  1.00 49.51  ? 90  ASP F C   1 
ATOM   12112 O  O   . ASP F 1 90  ? 55.697  7.808   61.070  1.00 56.86  ? 90  ASP F O   1 
ATOM   12113 C  CB  . ASP F 1 90  ? 56.270  10.301  59.776  1.00 46.43  ? 90  ASP F CB  1 
ATOM   12114 C  CG  . ASP F 1 90  ? 57.319  10.597  58.722  1.00 58.76  ? 90  ASP F CG  1 
ATOM   12115 O  OD1 . ASP F 1 90  ? 56.946  11.242  57.706  1.00 71.31  ? 90  ASP F OD1 1 
ATOM   12116 O  OD2 . ASP F 1 90  ? 58.444  10.065  58.840  1.00 58.71  ? 90  ASP F OD2 1 
ATOM   12117 N  N   . GLY F 1 91  ? 55.139  6.869   59.134  1.00 50.08  ? 91  GLY F N   1 
ATOM   12118 C  CA  . GLY F 1 91  ? 55.028  5.557   59.726  1.00 47.74  ? 91  GLY F CA  1 
ATOM   12119 C  C   . GLY F 1 91  ? 56.384  4.882   59.784  1.00 41.73  ? 91  GLY F C   1 
ATOM   12120 O  O   . GLY F 1 91  ? 57.324  5.271   59.120  1.00 40.09  ? 91  GLY F O   1 
ATOM   12121 N  N   . PRO F 1 92  ? 56.481  3.800   60.551  1.00 42.04  ? 92  PRO F N   1 
ATOM   12122 C  CA  . PRO F 1 92  ? 57.753  3.096   60.638  1.00 38.96  ? 92  PRO F CA  1 
ATOM   12123 C  C   . PRO F 1 92  ? 58.306  2.663   59.275  1.00 42.12  ? 92  PRO F C   1 
ATOM   12124 O  O   . PRO F 1 92  ? 59.525  2.669   59.086  1.00 40.87  ? 92  PRO F O   1 
ATOM   12125 C  CB  . PRO F 1 92  ? 57.424  1.903   61.585  1.00 41.83  ? 92  PRO F CB  1 
ATOM   12126 C  CG  . PRO F 1 92  ? 55.894  1.905   61.802  1.00 43.08  ? 92  PRO F CG  1 
ATOM   12127 C  CD  . PRO F 1 92  ? 55.357  3.229   61.336  1.00 41.44  ? 92  PRO F CD  1 
ATOM   12128 N  N   . VAL F 1 93  ? 57.417  2.265   58.341  1.00 43.56  ? 93  VAL F N   1 
ATOM   12129 C  CA  . VAL F 1 93  ? 57.839  1.783   57.023  1.00 40.42  ? 93  VAL F CA  1 
ATOM   12130 C  C   . VAL F 1 93  ? 57.373  2.727   55.911  1.00 41.23  ? 93  VAL F C   1 
ATOM   12131 O  O   . VAL F 1 93  ? 58.170  3.062   55.041  1.00 45.45  ? 93  VAL F O   1 
ATOM   12132 C  CB  . VAL F 1 93  ? 57.375  0.347   56.731  1.00 37.82  ? 93  VAL F CB  1 
ATOM   12133 C  CG1 . VAL F 1 93  ? 57.705  -0.103  55.309  1.00 30.68  ? 93  VAL F CG1 1 
ATOM   12134 C  CG2 . VAL F 1 93  ? 57.939  -0.614  57.769  1.00 39.15  ? 93  VAL F CG2 1 
ATOM   12135 N  N   . HIS F 1 94  ? 56.095  3.146   55.931  1.00 39.02  ? 94  HIS F N   1 
ATOM   12136 C  CA  . HIS F 1 94  ? 55.494  3.880   54.821  1.00 31.36  ? 94  HIS F CA  1 
ATOM   12137 C  C   . HIS F 1 94  ? 55.058  5.265   55.282  1.00 32.12  ? 94  HIS F C   1 
ATOM   12138 O  O   . HIS F 1 94  ? 54.648  5.434   56.408  1.00 37.90  ? 94  HIS F O   1 
ATOM   12139 C  CB  . HIS F 1 94  ? 54.302  3.096   54.283  1.00 29.06  ? 94  HIS F CB  1 
ATOM   12140 C  CG  . HIS F 1 94  ? 54.577  1.696   53.773  1.00 31.72  ? 94  HIS F CG  1 
ATOM   12141 N  ND1 . HIS F 1 94  ? 55.235  1.438   52.575  1.00 28.27  ? 94  HIS F ND1 1 
ATOM   12142 C  CD2 . HIS F 1 94  ? 54.212  0.460   54.289  1.00 30.10  ? 94  HIS F CD2 1 
ATOM   12143 C  CE1 . HIS F 1 94  ? 55.257  0.112   52.366  1.00 24.91  ? 94  HIS F CE1 1 
ATOM   12144 N  NE2 . HIS F 1 94  ? 54.655  -0.500  53.400  1.00 27.62  ? 94  HIS F NE2 1 
ATOM   12145 N  N   . ARG F 1 95  ? 55.082  6.225   54.373  1.00 34.86  ? 95  ARG F N   1 
ATOM   12146 C  CA  . ARG F 1 95  ? 54.864  7.641   54.625  1.00 38.27  ? 95  ARG F CA  1 
ATOM   12147 C  C   . ARG F 1 95  ? 53.717  8.155   53.732  1.00 35.01  ? 95  ARG F C   1 
ATOM   12148 O  O   . ARG F 1 95  ? 53.719  8.072   52.511  1.00 36.39  ? 95  ARG F O   1 
ATOM   12149 C  CB  . ARG F 1 95  ? 56.256  8.258   54.342  1.00 48.20  ? 95  ARG F CB  1 
ATOM   12150 C  CG  . ARG F 1 95  ? 56.482  9.765   54.375  1.00 52.86  ? 95  ARG F CG  1 
ATOM   12151 C  CD  . ARG F 1 95  ? 57.950  10.119  54.244  1.00 51.06  ? 95  ARG F CD  1 
ATOM   12152 N  NE  . ARG F 1 95  ? 58.118  11.549  53.988  1.00 54.34  ? 95  ARG F NE  1 
ATOM   12153 N  N   . ALA F 1 96  ? 52.720  8.771   54.330  1.00 35.12  ? 96  ALA F N   1 
ATOM   12154 C  CA  . ALA F 1 96  ? 51.725  9.519   53.586  1.00 35.69  ? 96  ALA F CA  1 
ATOM   12155 C  C   . ALA F 1 96  ? 52.161  10.975  53.459  1.00 34.72  ? 96  ALA F C   1 
ATOM   12156 O  O   . ALA F 1 96  ? 51.995  11.744  54.415  1.00 36.40  ? 96  ALA F O   1 
ATOM   12157 C  CB  . ALA F 1 96  ? 50.388  9.404   54.324  1.00 38.24  ? 96  ALA F CB  1 
ATOM   12158 N  N   . VAL F 1 97  ? 52.654  11.359  52.277  1.00 32.94  ? 97  VAL F N   1 
ATOM   12159 C  CA  . VAL F 1 97  ? 53.078  12.742  52.091  1.00 35.74  ? 97  VAL F CA  1 
ATOM   12160 C  C   . VAL F 1 97  ? 51.888  13.673  51.886  1.00 35.24  ? 97  VAL F C   1 
ATOM   12161 O  O   . VAL F 1 97  ? 50.798  13.218  51.485  1.00 38.30  ? 97  VAL F O   1 
ATOM   12162 C  CB  . VAL F 1 97  ? 54.034  12.915  50.917  1.00 38.33  ? 97  VAL F CB  1 
ATOM   12163 C  CG1 . VAL F 1 97  ? 55.242  12.022  51.087  1.00 48.79  ? 97  VAL F CG1 1 
ATOM   12164 C  CG2 . VAL F 1 97  ? 53.345  12.581  49.609  1.00 42.04  ? 97  VAL F CG2 1 
ATOM   12165 N  N   . ALA F 1 98  ? 52.195  14.958  52.160  1.00 31.81  ? 98  ALA F N   1 
ATOM   12166 C  CA  . ALA F 1 98  ? 51.330  16.112  51.974  1.00 29.93  ? 98  ALA F CA  1 
ATOM   12167 C  C   . ALA F 1 98  ? 51.922  16.976  50.887  1.00 28.81  ? 98  ALA F C   1 
ATOM   12168 O  O   . ALA F 1 98  ? 53.064  17.375  51.018  1.00 35.33  ? 98  ALA F O   1 
ATOM   12169 C  CB  . ALA F 1 98  ? 51.213  16.956  53.214  1.00 27.75  ? 98  ALA F CB  1 
ATOM   12170 N  N   . THR F 1 99  ? 51.128  17.298  49.872  1.00 26.84  ? 99  THR F N   1 
ATOM   12171 C  CA  . THR F 1 99  ? 51.636  18.036  48.732  1.00 26.52  ? 99  THR F CA  1 
ATOM   12172 C  C   . THR F 1 99  ? 50.727  19.225  48.526  1.00 25.77  ? 99  THR F C   1 
ATOM   12173 O  O   . THR F 1 99  ? 49.604  19.234  48.978  1.00 27.23  ? 99  THR F O   1 
ATOM   12174 C  CB  . THR F 1 99  ? 51.762  17.144  47.491  1.00 26.20  ? 99  THR F CB  1 
ATOM   12175 O  OG1 . THR F 1 99  ? 50.515  16.507  47.252  1.00 27.14  ? 99  THR F OG1 1 
ATOM   12176 C  CG2 . THR F 1 99  ? 52.745  16.021  47.728  1.00 25.78  ? 99  THR F CG2 1 
ATOM   12177 N  N   . PRO F 1 100 ? 51.223  20.298  47.898  1.00 28.72  ? 100 PRO F N   1 
ATOM   12178 C  CA  . PRO F 1 100 ? 50.435  21.517  47.696  1.00 27.78  ? 100 PRO F CA  1 
ATOM   12179 C  C   . PRO F 1 100 ? 49.232  21.284  46.801  1.00 28.78  ? 100 PRO F C   1 
ATOM   12180 O  O   . PRO F 1 100 ? 49.313  20.487  45.865  1.00 26.34  ? 100 PRO F O   1 
ATOM   12181 C  CB  . PRO F 1 100 ? 51.395  22.459  46.989  1.00 27.94  ? 100 PRO F CB  1 
ATOM   12182 C  CG  . PRO F 1 100 ? 52.749  21.819  47.127  1.00 29.72  ? 100 PRO F CG  1 
ATOM   12183 C  CD  . PRO F 1 100 ? 52.582  20.360  47.345  1.00 27.53  ? 100 PRO F CD  1 
ATOM   12184 N  N   . GLY F 1 101 ? 48.176  22.055  47.079  1.00 31.51  ? 101 GLY F N   1 
ATOM   12185 C  CA  . GLY F 1 101 ? 46.920  22.035  46.336  1.00 31.43  ? 101 GLY F CA  1 
ATOM   12186 C  C   . GLY F 1 101 ? 45.866  22.959  46.966  1.00 27.45  ? 101 GLY F C   1 
ATOM   12187 O  O   . GLY F 1 101 ? 45.389  22.757  48.070  1.00 27.45  ? 101 GLY F O   1 
ATOM   12188 N  N   . ASP F 1 102 ? 45.484  23.999  46.268  1.00 26.07  ? 102 ASP F N   1 
ATOM   12189 C  CA  . ASP F 1 102 ? 44.525  24.942  46.805  1.00 28.19  ? 102 ASP F CA  1 
ATOM   12190 C  C   . ASP F 1 102 ? 43.130  24.640  46.271  1.00 27.56  ? 102 ASP F C   1 
ATOM   12191 O  O   . ASP F 1 102 ? 42.126  24.901  46.923  1.00 30.16  ? 102 ASP F O   1 
ATOM   12192 C  CB  . ASP F 1 102 ? 44.940  26.361  46.438  1.00 30.43  ? 102 ASP F CB  1 
ATOM   12193 C  CG  . ASP F 1 102 ? 46.149  26.904  47.187  1.00 31.39  ? 102 ASP F CG  1 
ATOM   12194 O  OD1 . ASP F 1 102 ? 46.441  26.361  48.292  1.00 27.73  ? 102 ASP F OD1 1 
ATOM   12195 O  OD2 . ASP F 1 102 ? 46.764  27.860  46.642  1.00 31.81  ? 102 ASP F OD2 1 
ATOM   12196 N  N   . LEU F 1 103 ? 43.076  24.182  45.021  1.00 28.97  ? 103 LEU F N   1 
ATOM   12197 C  CA  . LEU F 1 103 ? 41.823  23.963  44.325  1.00 26.34  ? 103 LEU F CA  1 
ATOM   12198 C  C   . LEU F 1 103 ? 41.879  22.568  43.772  1.00 22.82  ? 103 LEU F C   1 
ATOM   12199 O  O   . LEU F 1 103 ? 42.923  22.189  43.271  1.00 22.23  ? 103 LEU F O   1 
ATOM   12200 C  CB  . LEU F 1 103 ? 41.577  24.953  43.192  1.00 26.57  ? 103 LEU F CB  1 
ATOM   12201 C  CG  . LEU F 1 103 ? 41.260  26.384  43.620  1.00 29.55  ? 103 LEU F CG  1 
ATOM   12202 C  CD1 . LEU F 1 103 ? 41.009  27.253  42.403  1.00 33.42  ? 103 LEU F CD1 1 
ATOM   12203 C  CD2 . LEU F 1 103 ? 40.064  26.434  44.534  1.00 33.22  ? 103 LEU F CD2 1 
ATOM   12204 N  N   . LEU F 1 104 ? 40.758  21.856  43.942  1.00 24.61  ? 104 LEU F N   1 
ATOM   12205 C  CA  . LEU F 1 104 ? 40.517  20.576  43.299  1.00 24.05  ? 104 LEU F CA  1 
ATOM   12206 C  C   . LEU F 1 104 ? 39.322  20.675  42.369  1.00 24.53  ? 104 LEU F C   1 
ATOM   12207 O  O   . LEU F 1 104 ? 38.262  21.178  42.760  1.00 24.12  ? 104 LEU F O   1 
ATOM   12208 C  CB  . LEU F 1 104 ? 40.233  19.517  44.345  1.00 24.26  ? 104 LEU F CB  1 
ATOM   12209 C  CG  . LEU F 1 104 ? 39.706  18.214  43.782  1.00 23.54  ? 104 LEU F CG  1 
ATOM   12210 C  CD1 . LEU F 1 104 ? 40.846  17.485  43.095  1.00 23.59  ? 104 LEU F CD1 1 
ATOM   12211 C  CD2 . LEU F 1 104 ? 39.151  17.472  44.955  1.00 26.93  ? 104 LEU F CD2 1 
ATOM   12212 N  N   . PHE F 1 105 ? 39.513  20.171  41.140  1.00 24.89  ? 105 PHE F N   1 
ATOM   12213 C  CA  . PHE F 1 105 ? 38.398  19.953  40.240  1.00 23.43  ? 105 PHE F CA  1 
ATOM   12214 C  C   . PHE F 1 105 ? 38.320  18.467  39.989  1.00 20.26  ? 105 PHE F C   1 
ATOM   12215 O  O   . PHE F 1 105 ? 39.261  17.909  39.449  1.00 20.18  ? 105 PHE F O   1 
ATOM   12216 C  CB  . PHE F 1 105 ? 38.559  20.760  38.964  1.00 23.99  ? 105 PHE F CB  1 
ATOM   12217 C  CG  . PHE F 1 105 ? 38.623  22.245  39.262  1.00 24.02  ? 105 PHE F CG  1 
ATOM   12218 C  CD1 . PHE F 1 105 ? 37.481  22.973  39.568  1.00 26.02  ? 105 PHE F CD1 1 
ATOM   12219 C  CD2 . PHE F 1 105 ? 39.826  22.901  39.218  1.00 24.14  ? 105 PHE F CD2 1 
ATOM   12220 C  CE1 . PHE F 1 105 ? 37.555  24.335  39.782  1.00 25.21  ? 105 PHE F CE1 1 
ATOM   12221 C  CE2 . PHE F 1 105 ? 39.881  24.265  39.458  1.00 23.69  ? 105 PHE F CE2 1 
ATOM   12222 C  CZ  . PHE F 1 105 ? 38.753  24.970  39.748  1.00 22.81  ? 105 PHE F CZ  1 
ATOM   12223 N  N   . HIS F 1 106 ? 37.198  17.867  40.429  1.00 20.63  ? 106 HIS F N   1 
ATOM   12224 C  CA  . HIS F 1 106 ? 36.944  16.444  40.272  1.00 19.27  ? 106 HIS F CA  1 
ATOM   12225 C  C   . HIS F 1 106 ? 35.879  16.341  39.204  1.00 20.02  ? 106 HIS F C   1 
ATOM   12226 O  O   . HIS F 1 106 ? 34.706  16.588  39.495  1.00 22.89  ? 106 HIS F O   1 
ATOM   12227 C  CB  . HIS F 1 106 ? 36.565  15.781  41.596  1.00 17.95  ? 106 HIS F CB  1 
ATOM   12228 C  CG  . HIS F 1 106 ? 36.296  14.325  41.466  1.00 19.44  ? 106 HIS F CG  1 
ATOM   12229 N  ND1 . HIS F 1 106 ? 35.540  13.609  42.374  1.00 21.00  ? 106 HIS F ND1 1 
ATOM   12230 C  CD2 . HIS F 1 106 ? 36.670  13.430  40.541  1.00 20.16  ? 106 HIS F CD2 1 
ATOM   12231 C  CE1 . HIS F 1 106 ? 35.503  12.324  42.008  1.00 21.07  ? 106 HIS F CE1 1 
ATOM   12232 N  NE2 . HIS F 1 106 ? 36.163  12.183  40.886  1.00 18.72  ? 106 HIS F NE2 1 
ATOM   12233 N  N   . ILE F 1 107 ? 36.351  16.125  37.967  1.00 18.90  ? 107 ILE F N   1 
ATOM   12234 C  CA  . ILE F 1 107 ? 35.478  16.127  36.803  1.00 21.24  ? 107 ILE F CA  1 
ATOM   12235 C  C   . ILE F 1 107 ? 35.232  14.685  36.338  1.00 21.53  ? 107 ILE F C   1 
ATOM   12236 O  O   . ILE F 1 107 ? 36.189  13.889  36.180  1.00 20.39  ? 107 ILE F O   1 
ATOM   12237 C  CB  . ILE F 1 107 ? 36.080  16.986  35.687  1.00 22.25  ? 107 ILE F CB  1 
ATOM   12238 C  CG1 . ILE F 1 107 ? 36.333  18.427  36.185  1.00 21.75  ? 107 ILE F CG1 1 
ATOM   12239 C  CG2 . ILE F 1 107 ? 35.197  16.910  34.434  1.00 22.35  ? 107 ILE F CG2 1 
ATOM   12240 C  CD1 . ILE F 1 107 ? 37.245  19.217  35.272  1.00 21.83  ? 107 ILE F CD1 1 
ATOM   12241 N  N   . ARG F 1 108 ? 33.939  14.343  36.189  1.00 21.10  ? 108 ARG F N   1 
ATOM   12242 C  CA  . ARG F 1 108 ? 33.564  12.992  35.821  1.00 21.50  ? 108 ARG F CA  1 
ATOM   12243 C  C   . ARG F 1 108 ? 32.526  13.063  34.723  1.00 21.98  ? 108 ARG F C   1 
ATOM   12244 O  O   . ARG F 1 108 ? 31.791  14.043  34.612  1.00 23.06  ? 108 ARG F O   1 
ATOM   12245 C  CB  . ARG F 1 108 ? 32.956  12.219  36.981  1.00 23.56  ? 108 ARG F CB  1 
ATOM   12246 C  CG  . ARG F 1 108 ? 33.976  11.852  38.042  1.00 23.88  ? 108 ARG F CG  1 
ATOM   12247 C  CD  . ARG F 1 108 ? 33.300  11.362  39.303  1.00 24.83  ? 108 ARG F CD  1 
ATOM   12248 N  NE  . ARG F 1 108 ? 32.611  12.419  40.066  1.00 25.61  ? 108 ARG F NE  1 
ATOM   12249 C  CZ  . ARG F 1 108 ? 32.103  12.169  41.264  1.00 29.00  ? 108 ARG F CZ  1 
ATOM   12250 N  NH1 . ARG F 1 108 ? 32.299  10.999  41.829  1.00 29.95  ? 108 ARG F NH1 1 
ATOM   12251 N  NH2 . ARG F 1 108 ? 31.460  13.073  41.950  1.00 32.83  ? 108 ARG F NH2 1 
ATOM   12252 N  N   . ALA F 1 109 ? 32.530  12.019  33.911  1.00 22.07  ? 109 ALA F N   1 
ATOM   12253 C  CA  . ALA F 1 109 ? 31.547  11.857  32.861  1.00 24.01  ? 109 ALA F CA  1 
ATOM   12254 C  C   . ALA F 1 109 ? 31.631  10.440  32.308  1.00 26.52  ? 109 ALA F C   1 
ATOM   12255 O  O   . ALA F 1 109 ? 32.528  9.668   32.661  1.00 24.03  ? 109 ALA F O   1 
ATOM   12256 C  CB  . ALA F 1 109 ? 31.835  12.864  31.783  1.00 27.18  ? 109 ALA F CB  1 
ATOM   12257 N  N   . SER F 1 110 ? 30.726  10.111  31.388  1.00 28.94  ? 110 SER F N   1 
ATOM   12258 C  CA  . SER F 1 110 ? 30.823  8.824   30.715  1.00 31.00  ? 110 SER F CA  1 
ATOM   12259 C  C   . SER F 1 110 ? 31.858  8.836   29.593  1.00 32.30  ? 110 SER F C   1 
ATOM   12260 O  O   . SER F 1 110 ? 32.077  7.818   28.987  1.00 36.07  ? 110 SER F O   1 
ATOM   12261 C  CB  . SER F 1 110 ? 29.482  8.364   30.216  1.00 30.13  ? 110 SER F CB  1 
ATOM   12262 O  OG  . SER F 1 110 ? 29.020  9.286   29.252  1.00 31.20  ? 110 SER F OG  1 
ATOM   12263 N  N   . ARG F 1 111 ? 32.500  9.956   29.281  1.00 35.75  ? 111 ARG F N   1 
ATOM   12264 C  CA  . ARG F 1 111 ? 33.453  9.976   28.172  1.00 34.65  ? 111 ARG F CA  1 
ATOM   12265 C  C   . ARG F 1 111 ? 34.487  11.023  28.519  1.00 27.71  ? 111 ARG F C   1 
ATOM   12266 O  O   . ARG F 1 111 ? 34.143  12.079  29.018  1.00 26.65  ? 111 ARG F O   1 
ATOM   12267 C  CB  . ARG F 1 111 ? 32.886  10.461  26.827  1.00 43.90  ? 111 ARG F CB  1 
ATOM   12268 C  CG  . ARG F 1 111 ? 31.430  10.169  26.466  1.00 52.70  ? 111 ARG F CG  1 
ATOM   12269 C  CD  . ARG F 1 111 ? 30.823  10.894  25.213  1.00 55.51  ? 111 ARG F CD  1 
ATOM   12270 N  NE  . ARG F 1 111 ? 31.693  11.126  24.039  1.00 76.38  ? 111 ARG F NE  1 
ATOM   12271 C  CZ  . ARG F 1 111 ? 32.251  10.349  23.043  1.00 71.24  ? 111 ARG F CZ  1 
ATOM   12272 N  NH1 . ARG F 1 111 ? 32.064  9.050   22.917  1.00 63.63  ? 111 ARG F NH1 1 
ATOM   12273 N  NH2 . ARG F 1 111 ? 33.036  10.894  22.124  1.00 77.00  ? 111 ARG F NH2 1 
ATOM   12274 N  N   . LEU F 1 112 ? 35.739  10.753  28.232  1.00 24.98  ? 112 LEU F N   1 
ATOM   12275 C  CA  . LEU F 1 112 ? 36.795  11.680  28.612  1.00 26.80  ? 112 LEU F CA  1 
ATOM   12276 C  C   . LEU F 1 112 ? 36.734  13.050  27.907  1.00 28.14  ? 112 LEU F C   1 
ATOM   12277 O  O   . LEU F 1 112 ? 37.243  14.010  28.460  1.00 27.66  ? 112 LEU F O   1 
ATOM   12278 C  CB  . LEU F 1 112 ? 38.111  10.990  28.308  1.00 25.31  ? 112 LEU F CB  1 
ATOM   12279 C  CG  . LEU F 1 112 ? 39.376  11.765  28.663  1.00 30.81  ? 112 LEU F CG  1 
ATOM   12280 C  CD1 . LEU F 1 112 ? 39.511  12.059  30.137  1.00 33.38  ? 112 LEU F CD1 1 
ATOM   12281 C  CD2 . LEU F 1 112 ? 40.593  10.991  28.183  1.00 31.60  ? 112 LEU F CD2 1 
ATOM   12282 N  N   . ASP F 1 113 ? 36.175  13.146  26.696  1.00 27.86  ? 113 ASP F N   1 
ATOM   12283 C  CA  . ASP F 1 113 ? 36.199  14.380  25.938  1.00 29.91  ? 113 ASP F CA  1 
ATOM   12284 C  C   . ASP F 1 113 ? 35.349  15.438  26.626  1.00 27.78  ? 113 ASP F C   1 
ATOM   12285 O  O   . ASP F 1 113 ? 35.622  16.630  26.479  1.00 31.03  ? 113 ASP F O   1 
ATOM   12286 C  CB  . ASP F 1 113 ? 35.641  14.245  24.525  1.00 35.60  ? 113 ASP F CB  1 
ATOM   12287 C  CG  . ASP F 1 113 ? 34.290  13.548  24.392  1.00 33.91  ? 113 ASP F CG  1 
ATOM   12288 O  OD1 . ASP F 1 113 ? 34.317  12.325  24.709  1.00 34.13  ? 113 ASP F OD1 1 
ATOM   12289 O  OD2 . ASP F 1 113 ? 33.273  14.191  23.906  1.00 27.49  ? 113 ASP F OD2 1 
ATOM   12290 N  N   . LEU F 1 114 ? 34.270  15.025  27.296  1.00 26.55  ? 114 LEU F N   1 
ATOM   12291 C  CA  . LEU F 1 114 ? 33.438  16.000  27.987  1.00 26.54  ? 114 LEU F CA  1 
ATOM   12292 C  C   . LEU F 1 114 ? 34.225  16.574  29.152  1.00 25.00  ? 114 LEU F C   1 
ATOM   12293 O  O   . LEU F 1 114 ? 34.124  17.777  29.407  1.00 22.85  ? 114 LEU F O   1 
ATOM   12294 C  CB  . LEU F 1 114 ? 32.152  15.373  28.523  1.00 29.86  ? 114 LEU F CB  1 
ATOM   12295 C  CG  . LEU F 1 114 ? 31.085  14.993  27.500  1.00 28.16  ? 114 LEU F CG  1 
ATOM   12296 C  CD1 . LEU F 1 114 ? 30.073  14.036  28.129  1.00 27.56  ? 114 LEU F CD1 1 
ATOM   12297 C  CD2 . LEU F 1 114 ? 30.434  16.254  27.043  1.00 26.53  ? 114 LEU F CD2 1 
ATOM   12298 N  N   . CYS F 1 115 ? 34.918  15.660  29.876  1.00 23.82  ? 115 CYS F N   1 
ATOM   12299 C  CA  . CYS F 1 115 ? 35.785  16.044  30.981  1.00 24.82  ? 115 CYS F CA  1 
ATOM   12300 C  C   . CYS F 1 115 ? 36.814  17.077  30.513  1.00 24.57  ? 115 CYS F C   1 
ATOM   12301 O  O   . CYS F 1 115 ? 37.007  18.130  31.127  1.00 23.56  ? 115 CYS F O   1 
ATOM   12302 C  CB  . CYS F 1 115 ? 36.523  14.851  31.566  1.00 23.43  ? 115 CYS F CB  1 
ATOM   12303 S  SG  . CYS F 1 115 ? 35.430  13.640  32.352  1.00 23.09  ? 115 CYS F SG  1 
ATOM   12304 N  N   . PHE F 1 116 ? 37.469  16.758  29.403  1.00 22.28  ? 116 PHE F N   1 
ATOM   12305 C  CA  . PHE F 1 116 ? 38.505  17.611  28.857  1.00 20.94  ? 116 PHE F CA  1 
ATOM   12306 C  C   . PHE F 1 116 ? 37.938  18.969  28.451  1.00 19.12  ? 116 PHE F C   1 
ATOM   12307 O  O   . PHE F 1 116 ? 38.563  20.001  28.650  1.00 20.57  ? 116 PHE F O   1 
ATOM   12308 C  CB  . PHE F 1 116 ? 39.124  16.851  27.683  1.00 23.84  ? 116 PHE F CB  1 
ATOM   12309 C  CG  . PHE F 1 116 ? 40.422  17.487  27.217  1.00 27.24  ? 116 PHE F CG  1 
ATOM   12310 C  CD1 . PHE F 1 116 ? 41.629  17.126  27.790  1.00 29.93  ? 116 PHE F CD1 1 
ATOM   12311 C  CD2 . PHE F 1 116 ? 40.425  18.460  26.230  1.00 31.90  ? 116 PHE F CD2 1 
ATOM   12312 C  CE1 . PHE F 1 116 ? 42.805  17.715  27.384  1.00 32.39  ? 116 PHE F CE1 1 
ATOM   12313 C  CE2 . PHE F 1 116 ? 41.605  19.060  25.840  1.00 29.36  ? 116 PHE F CE2 1 
ATOM   12314 C  CZ  . PHE F 1 116 ? 42.787  18.680  26.406  1.00 33.03  ? 116 PHE F CZ  1 
ATOM   12315 N  N   . ALA F 1 117 ? 36.782  18.964  27.816  1.00 18.49  ? 117 ALA F N   1 
ATOM   12316 C  CA  . ALA F 1 117 ? 36.165  20.200  27.388  1.00 20.74  ? 117 ALA F CA  1 
ATOM   12317 C  C   . ALA F 1 117 ? 35.905  21.111  28.578  1.00 20.51  ? 117 ALA F C   1 
ATOM   12318 O  O   . ALA F 1 117 ? 36.151  22.295  28.525  1.00 21.26  ? 117 ALA F O   1 
ATOM   12319 C  CB  . ALA F 1 117 ? 34.879  19.871  26.687  1.00 20.16  ? 117 ALA F CB  1 
ATOM   12320 N  N   . LEU F 1 118 ? 35.390  20.543  29.659  1.00 21.20  ? 118 LEU F N   1 
ATOM   12321 C  CA  . LEU F 1 118 ? 35.087  21.353  30.823  1.00 21.36  ? 118 LEU F CA  1 
ATOM   12322 C  C   . LEU F 1 118 ? 36.403  21.804  31.486  1.00 21.50  ? 118 LEU F C   1 
ATOM   12323 O  O   . LEU F 1 118 ? 36.544  22.973  31.871  1.00 19.80  ? 118 LEU F O   1 
ATOM   12324 C  CB  . LEU F 1 118 ? 34.158  20.607  31.786  1.00 20.95  ? 118 LEU F CB  1 
ATOM   12325 C  CG  . LEU F 1 118 ? 33.899  21.361  33.091  1.00 20.38  ? 118 LEU F CG  1 
ATOM   12326 C  CD1 . LEU F 1 118 ? 33.309  22.729  32.831  1.00 21.63  ? 118 LEU F CD1 1 
ATOM   12327 C  CD2 . LEU F 1 118 ? 33.007  20.624  34.008  1.00 20.51  ? 118 LEU F CD2 1 
ATOM   12328 N  N   . ALA F 1 119 ? 37.388  20.898  31.584  1.00 20.41  ? 119 ALA F N   1 
ATOM   12329 C  CA  . ALA F 1 119 ? 38.676  21.267  32.149  1.00 21.62  ? 119 ALA F CA  1 
ATOM   12330 C  C   . ALA F 1 119 ? 39.315  22.424  31.370  1.00 23.58  ? 119 ALA F C   1 
ATOM   12331 O  O   . ALA F 1 119 ? 39.919  23.322  31.948  1.00 23.49  ? 119 ALA F O   1 
ATOM   12332 C  CB  . ALA F 1 119 ? 39.569  20.049  32.160  1.00 23.30  ? 119 ALA F CB  1 
ATOM   12333 N  N   . THR F 1 120 ? 39.199  22.375  30.040  1.00 22.90  ? 120 THR F N   1 
ATOM   12334 C  CA  . THR F 1 120 ? 39.723  23.400  29.170  1.00 22.03  ? 120 THR F CA  1 
ATOM   12335 C  C   . THR F 1 120 ? 39.052  24.713  29.524  1.00 21.92  ? 120 THR F C   1 
ATOM   12336 O  O   . THR F 1 120 ? 39.727  25.721  29.605  1.00 22.93  ? 120 THR F O   1 
ATOM   12337 C  CB  . THR F 1 120 ? 39.472  22.992  27.710  1.00 23.59  ? 120 THR F CB  1 
ATOM   12338 O  OG1 . THR F 1 120 ? 40.393  21.920  27.516  1.00 24.96  ? 120 THR F OG1 1 
ATOM   12339 C  CG2 . THR F 1 120 ? 39.731  24.067  26.678  1.00 24.40  ? 120 THR F CG2 1 
ATOM   12340 N  N   . GLU F 1 121 ? 37.731  24.729  29.666  1.00 22.53  ? 121 GLU F N   1 
ATOM   12341 C  CA  . GLU F 1 121 ? 37.044  25.984  29.883  1.00 27.02  ? 121 GLU F CA  1 
ATOM   12342 C  C   . GLU F 1 121 ? 37.429  26.609  31.233  1.00 28.14  ? 121 GLU F C   1 
ATOM   12343 O  O   . GLU F 1 121 ? 37.612  27.816  31.323  1.00 24.75  ? 121 GLU F O   1 
ATOM   12344 C  CB  . GLU F 1 121 ? 35.537  25.762  29.806  1.00 29.56  ? 121 GLU F CB  1 
ATOM   12345 C  CG  . GLU F 1 121 ? 34.959  25.899  28.408  1.00 32.34  ? 121 GLU F CG  1 
ATOM   12346 C  CD  . GLU F 1 121 ? 34.978  27.349  27.969  1.00 33.98  ? 121 GLU F CD  1 
ATOM   12347 O  OE1 . GLU F 1 121 ? 35.013  28.374  28.733  1.00 34.95  ? 121 GLU F OE1 1 
ATOM   12348 O  OE2 . GLU F 1 121 ? 35.013  27.353  26.736  1.00 41.55  ? 121 GLU F OE2 1 
ATOM   12349 N  N   . ILE F 1 122 ? 37.511  25.771  32.278  1.00 31.15  ? 122 ILE F N   1 
ATOM   12350 C  CA  . ILE F 1 122 ? 37.868  26.201  33.628  1.00 30.82  ? 122 ILE F CA  1 
ATOM   12351 C  C   . ILE F 1 122 ? 39.264  26.809  33.602  1.00 27.75  ? 122 ILE F C   1 
ATOM   12352 O  O   . ILE F 1 122 ? 39.457  27.935  34.046  1.00 23.28  ? 122 ILE F O   1 
ATOM   12353 C  CB  . ILE F 1 122 ? 37.742  25.036  34.642  1.00 28.65  ? 122 ILE F CB  1 
ATOM   12354 C  CG1 . ILE F 1 122 ? 36.284  24.745  34.926  1.00 32.61  ? 122 ILE F CG1 1 
ATOM   12355 C  CG2 . ILE F 1 122 ? 38.490  25.268  35.950  1.00 27.34  ? 122 ILE F CG2 1 
ATOM   12356 C  CD1 . ILE F 1 122 ? 36.088  23.411  35.619  1.00 35.98  ? 122 ILE F CD1 1 
ATOM   12357 N  N   . MET F 1 123 ? 40.226  26.066  33.061  1.00 27.56  ? 123 MET F N   1 
ATOM   12358 C  CA  . MET F 1 123 ? 41.597  26.534  33.059  1.00 32.84  ? 123 MET F CA  1 
ATOM   12359 C  C   . MET F 1 123 ? 41.763  27.746  32.146  1.00 30.71  ? 123 MET F C   1 
ATOM   12360 O  O   . MET F 1 123 ? 42.636  28.577  32.376  1.00 33.33  ? 123 MET F O   1 
ATOM   12361 C  CB  . MET F 1 123 ? 42.515  25.394  32.644  1.00 36.05  ? 123 MET F CB  1 
ATOM   12362 C  CG  . MET F 1 123 ? 42.671  24.399  33.765  1.00 41.92  ? 123 MET F CG  1 
ATOM   12363 S  SD  . MET F 1 123 ? 43.776  24.996  35.059  1.00 51.84  ? 123 MET F SD  1 
ATOM   12364 C  CE  . MET F 1 123 ? 45.054  25.746  34.035  1.00 51.67  ? 123 MET F CE  1 
ATOM   12365 N  N   . GLY F 1 124 ? 40.918  27.827  31.125  1.00 27.39  ? 124 GLY F N   1 
ATOM   12366 C  CA  . GLY F 1 124 ? 40.820  29.000  30.289  1.00 29.69  ? 124 GLY F CA  1 
ATOM   12367 C  C   . GLY F 1 124 ? 40.634  30.250  31.126  1.00 29.54  ? 124 GLY F C   1 
ATOM   12368 O  O   . GLY F 1 124 ? 41.344  31.209  30.933  1.00 34.18  ? 124 GLY F O   1 
ATOM   12369 N  N   A ARG F 1 125 ? 39.703  30.217  32.078  0.60 29.81  ? 125 ARG F N   1 
ATOM   12370 N  N   B ARG F 1 125 ? 39.694  30.196  32.074  0.40 29.69  ? 125 ARG F N   1 
ATOM   12371 C  CA  A ARG F 1 125 ? 39.387  31.381  32.901  0.60 28.35  ? 125 ARG F CA  1 
ATOM   12372 C  CA  B ARG F 1 125 ? 39.329  31.353  32.883  0.40 28.41  ? 125 ARG F CA  1 
ATOM   12373 C  C   A ARG F 1 125 ? 40.485  31.628  33.942  0.60 28.93  ? 125 ARG F C   1 
ATOM   12374 C  C   B ARG F 1 125 ? 40.365  31.578  34.005  0.40 29.10  ? 125 ARG F C   1 
ATOM   12375 O  O   A ARG F 1 125 ? 40.655  32.736  34.443  0.60 26.45  ? 125 ARG F O   1 
ATOM   12376 O  O   B ARG F 1 125 ? 40.423  32.668  34.576  0.40 28.19  ? 125 ARG F O   1 
ATOM   12377 C  CB  A ARG F 1 125 ? 38.066  31.154  33.643  0.60 26.54  ? 125 ARG F CB  1 
ATOM   12378 C  CB  B ARG F 1 125 ? 37.863  31.173  33.314  0.40 26.79  ? 125 ARG F CB  1 
ATOM   12379 C  CG  A ARG F 1 125 ? 36.861  30.917  32.750  0.60 27.11  ? 125 ARG F CG  1 
ATOM   12380 C  CG  B ARG F 1 125 ? 36.773  31.428  32.270  0.40 26.68  ? 125 ARG F CG  1 
ATOM   12381 C  CD  A ARG F 1 125 ? 36.243  32.216  32.236  0.60 26.12  ? 125 ARG F CD  1 
ATOM   12382 C  CD  B ARG F 1 125 ? 36.500  30.343  31.181  0.40 25.46  ? 125 ARG F CD  1 
ATOM   12383 N  NE  A ARG F 1 125 ? 35.919  33.121  33.341  0.60 23.40  ? 125 ARG F NE  1 
ATOM   12384 N  NE  B ARG F 1 125 ? 35.418  30.672  30.243  0.40 22.33  ? 125 ARG F NE  1 
ATOM   12385 C  CZ  A ARG F 1 125 ? 34.766  33.056  33.958  0.60 24.39  ? 125 ARG F CZ  1 
ATOM   12386 C  CZ  B ARG F 1 125 ? 34.286  31.251  30.635  0.40 20.71  ? 125 ARG F CZ  1 
ATOM   12387 N  NH1 A ARG F 1 125 ? 33.725  32.527  33.323  0.60 26.77  ? 125 ARG F NH1 1 
ATOM   12388 N  NH1 B ARG F 1 125 ? 33.992  31.421  31.901  0.40 19.95  ? 125 ARG F NH1 1 
ATOM   12389 N  NH2 A ARG F 1 125 ? 34.642  33.513  35.195  0.60 23.21  ? 125 ARG F NH2 1 
ATOM   12390 N  NH2 B ARG F 1 125 ? 33.437  31.696  29.757  0.40 20.92  ? 125 ARG F NH2 1 
ATOM   12391 N  N   . LEU F 1 126 ? 41.222  30.576  34.298  1.00 28.57  ? 126 LEU F N   1 
ATOM   12392 C  CA  . LEU F 1 126 ? 42.172  30.668  35.382  1.00 27.95  ? 126 LEU F CA  1 
ATOM   12393 C  C   . LEU F 1 126 ? 43.593  30.917  34.920  1.00 33.86  ? 126 LEU F C   1 
ATOM   12394 O  O   . LEU F 1 126 ? 44.398  31.095  35.822  1.00 34.93  ? 126 LEU F O   1 
ATOM   12395 C  CB  . LEU F 1 126 ? 42.121  29.386  36.197  1.00 27.06  ? 126 LEU F CB  1 
ATOM   12396 C  CG  . LEU F 1 126 ? 40.843  29.166  37.028  1.00 28.82  ? 126 LEU F CG  1 
ATOM   12397 C  CD1 . LEU F 1 126 ? 40.908  27.882  37.906  1.00 27.45  ? 126 LEU F CD1 1 
ATOM   12398 C  CD2 . LEU F 1 126 ? 40.453  30.390  37.904  1.00 30.14  ? 126 LEU F CD2 1 
ATOM   12399 N  N   . ARG F 1 127 ? 43.900  30.872  33.598  1.00 41.63  ? 127 ARG F N   1 
ATOM   12400 C  CA  . ARG F 1 127 ? 45.273  30.974  33.080  1.00 40.37  ? 127 ARG F CA  1 
ATOM   12401 C  C   . ARG F 1 127 ? 45.775  32.324  33.605  1.00 37.57  ? 127 ARG F C   1 
ATOM   12402 O  O   . ARG F 1 127 ? 45.031  33.296  33.741  1.00 34.88  ? 127 ARG F O   1 
ATOM   12403 C  CB  . ARG F 1 127 ? 45.479  30.669  31.570  1.00 34.34  ? 127 ARG F CB  1 
ATOM   12404 N  N   . GLY F 1 128 ? 46.998  32.357  34.100  1.00 38.19  ? 128 GLY F N   1 
ATOM   12405 C  CA  . GLY F 1 128 ? 47.466  33.589  34.704  1.00 37.73  ? 128 GLY F CA  1 
ATOM   12406 C  C   . GLY F 1 128 ? 47.313  33.624  36.220  1.00 37.89  ? 128 GLY F C   1 
ATOM   12407 O  O   . GLY F 1 128 ? 48.140  34.235  36.873  1.00 48.12  ? 128 GLY F O   1 
ATOM   12408 N  N   . ALA F 1 129 ? 46.295  32.981  36.802  1.00 30.36  ? 129 ALA F N   1 
ATOM   12409 C  CA  . ALA F 1 129 ? 46.027  33.150  38.227  1.00 26.07  ? 129 ALA F CA  1 
ATOM   12410 C  C   . ALA F 1 129 ? 46.378  31.916  39.049  1.00 24.96  ? 129 ALA F C   1 
ATOM   12411 O  O   . ALA F 1 129 ? 46.352  31.999  40.262  1.00 23.72  ? 129 ALA F O   1 
ATOM   12412 C  CB  . ALA F 1 129 ? 44.568  33.505  38.465  1.00 28.00  ? 129 ALA F CB  1 
ATOM   12413 N  N   . VAL F 1 130 ? 46.704  30.787  38.421  1.00 23.88  ? 130 VAL F N   1 
ATOM   12414 C  CA  . VAL F 1 130 ? 46.888  29.558  39.153  1.00 26.50  ? 130 VAL F CA  1 
ATOM   12415 C  C   . VAL F 1 130 ? 48.081  28.865  38.529  1.00 29.56  ? 130 VAL F C   1 
ATOM   12416 O  O   . VAL F 1 130 ? 48.494  29.231  37.442  1.00 35.42  ? 130 VAL F O   1 
ATOM   12417 C  CB  . VAL F 1 130 ? 45.680  28.598  39.129  1.00 28.59  ? 130 VAL F CB  1 
ATOM   12418 C  CG1 . VAL F 1 130 ? 44.435  29.181  39.772  1.00 29.53  ? 130 VAL F CG1 1 
ATOM   12419 C  CG2 . VAL F 1 130 ? 45.336  28.179  37.713  1.00 27.61  ? 130 VAL F CG2 1 
ATOM   12420 N  N   . THR F 1 131 ? 48.604  27.856  39.220  1.00 30.33  ? 131 THR F N   1 
ATOM   12421 C  CA  . THR F 1 131 ? 49.698  27.040  38.714  1.00 31.66  ? 131 THR F CA  1 
ATOM   12422 C  C   . THR F 1 131 ? 49.285  25.575  38.850  1.00 30.09  ? 131 THR F C   1 
ATOM   12423 O  O   . THR F 1 131 ? 48.982  25.132  39.974  1.00 26.56  ? 131 THR F O   1 
ATOM   12424 C  CB  . THR F 1 131 ? 50.983  27.309  39.519  1.00 35.18  ? 131 THR F CB  1 
ATOM   12425 O  OG1 . THR F 1 131 ? 51.391  28.671  39.442  1.00 34.44  ? 131 THR F OG1 1 
ATOM   12426 C  CG2 . THR F 1 131 ? 52.139  26.402  39.110  1.00 35.86  ? 131 THR F CG2 1 
ATOM   12427 N  N   . PRO F 1 132 ? 49.314  24.786  37.747  1.00 28.51  ? 132 PRO F N   1 
ATOM   12428 C  CA  . PRO F 1 132 ? 48.937  23.379  37.792  1.00 29.21  ? 132 PRO F CA  1 
ATOM   12429 C  C   . PRO F 1 132 ? 49.886  22.651  38.716  1.00 28.68  ? 132 PRO F C   1 
ATOM   12430 O  O   . PRO F 1 132 ? 51.054  22.937  38.648  1.00 32.83  ? 132 PRO F O   1 
ATOM   12431 C  CB  . PRO F 1 132 ? 49.092  22.908  36.357  1.00 28.66  ? 132 PRO F CB  1 
ATOM   12432 C  CG  . PRO F 1 132 ? 49.008  24.163  35.534  1.00 31.06  ? 132 PRO F CG  1 
ATOM   12433 C  CD  . PRO F 1 132 ? 49.679  25.210  36.395  1.00 29.40  ? 132 PRO F CD  1 
ATOM   12434 N  N   . GLN F 1 133 ? 49.387  21.757  39.574  1.00 30.32  ? 133 GLN F N   1 
ATOM   12435 C  CA  . GLN F 1 133 ? 50.222  20.874  40.375  1.00 28.82  ? 133 GLN F CA  1 
ATOM   12436 C  C   . GLN F 1 133 ? 50.064  19.413  39.971  1.00 25.57  ? 133 GLN F C   1 
ATOM   12437 O  O   . GLN F 1 133 ? 51.000  18.638  40.077  1.00 27.34  ? 133 GLN F O   1 
ATOM   12438 C  CB  . GLN F 1 133 ? 49.875  20.819  41.854  1.00 31.13  ? 133 GLN F CB  1 
ATOM   12439 C  CG  . GLN F 1 133 ? 50.070  22.139  42.568  1.00 35.02  ? 133 GLN F CG  1 
ATOM   12440 C  CD  . GLN F 1 133 ? 51.512  22.576  42.515  1.00 36.78  ? 133 GLN F CD  1 
ATOM   12441 O  OE1 . GLN F 1 133 ? 52.425  21.795  42.798  1.00 36.81  ? 133 GLN F OE1 1 
ATOM   12442 N  NE2 . GLN F 1 133 ? 51.716  23.792  42.029  1.00 37.18  ? 133 GLN F NE2 1 
ATOM   12443 N  N   . ASP F 1 134 ? 48.860  19.008  39.588  1.00 24.04  ? 134 ASP F N   1 
ATOM   12444 C  CA  . ASP F 1 134 ? 48.629  17.633  39.185  1.00 24.86  ? 134 ASP F CA  1 
ATOM   12445 C  C   . ASP F 1 134 ? 47.471  17.609  38.190  1.00 21.26  ? 134 ASP F C   1 
ATOM   12446 O  O   . ASP F 1 134 ? 46.526  18.400  38.288  1.00 23.55  ? 134 ASP F O   1 
ATOM   12447 C  CB  . ASP F 1 134 ? 48.393  16.786  40.425  1.00 26.52  ? 134 ASP F CB  1 
ATOM   12448 C  CG  . ASP F 1 134 ? 48.618  15.292  40.279  1.00 30.76  ? 134 ASP F CG  1 
ATOM   12449 O  OD1 . ASP F 1 134 ? 49.340  14.911  39.355  1.00 29.42  ? 134 ASP F OD1 1 
ATOM   12450 O  OD2 . ASP F 1 134 ? 48.033  14.509  41.072  1.00 32.94  ? 134 ASP F OD2 1 
ATOM   12451 N  N   . GLU F 1 135 ? 47.534  16.705  37.225  1.00 18.97  ? 135 GLU F N   1 
ATOM   12452 C  CA  . GLU F 1 135 ? 46.467  16.512  36.265  1.00 19.79  ? 135 GLU F CA  1 
ATOM   12453 C  C   . GLU F 1 135 ? 46.457  15.031  35.934  1.00 21.36  ? 135 GLU F C   1 
ATOM   12454 O  O   . GLU F 1 135 ? 47.472  14.524  35.526  1.00 23.92  ? 135 GLU F O   1 
ATOM   12455 C  CB  . GLU F 1 135 ? 46.699  17.297  34.983  1.00 21.17  ? 135 GLU F CB  1 
ATOM   12456 C  CG  . GLU F 1 135 ? 45.693  16.993  33.891  1.00 23.08  ? 135 GLU F CG  1 
ATOM   12457 C  CD  . GLU F 1 135 ? 45.874  17.842  32.668  1.00 26.18  ? 135 GLU F CD  1 
ATOM   12458 O  OE1 . GLU F 1 135 ? 46.805  18.683  32.671  1.00 24.62  ? 135 GLU F OE1 1 
ATOM   12459 O  OE2 . GLU F 1 135 ? 45.121  17.581  31.702  1.00 26.85  ? 135 GLU F OE2 1 
ATOM   12460 N  N   . VAL F 1 136 ? 45.343  14.328  36.152  1.00 22.43  ? 136 VAL F N   1 
ATOM   12461 C  CA  . VAL F 1 136 ? 45.305  12.896  35.919  1.00 20.66  ? 136 VAL F CA  1 
ATOM   12462 C  C   . VAL F 1 136 ? 44.054  12.583  35.146  1.00 19.12  ? 136 VAL F C   1 
ATOM   12463 O  O   . VAL F 1 136 ? 42.999  13.123  35.458  1.00 21.63  ? 136 VAL F O   1 
ATOM   12464 C  CB  . VAL F 1 136 ? 45.349  12.142  37.247  1.00 22.06  ? 136 VAL F CB  1 
ATOM   12465 C  CG1 . VAL F 1 136 ? 45.014  10.663  37.087  1.00 21.51  ? 136 VAL F CG1 1 
ATOM   12466 C  CG2 . VAL F 1 136 ? 46.705  12.346  37.910  1.00 22.34  ? 136 VAL F CG2 1 
ATOM   12467 N  N   . HIS F 1 137 ? 44.233  11.772  34.111  1.00 19.88  ? 137 HIS F N   1 
ATOM   12468 C  CA  . HIS F 1 137 ? 43.164  11.361  33.234  1.00 21.73  ? 137 HIS F CA  1 
ATOM   12469 C  C   . HIS F 1 137 ? 42.869  9.925   33.587  1.00 22.70  ? 137 HIS F C   1 
ATOM   12470 O  O   . HIS F 1 137 ? 43.714  9.066   33.408  1.00 26.20  ? 137 HIS F O   1 
ATOM   12471 C  CB  . HIS F 1 137 ? 43.593  11.498  31.774  1.00 21.04  ? 137 HIS F CB  1 
ATOM   12472 C  CG  . HIS F 1 137 ? 43.714  12.894  31.308  1.00 23.31  ? 137 HIS F CG  1 
ATOM   12473 N  ND1 . HIS F 1 137 ? 43.948  13.202  29.984  1.00 25.01  ? 137 HIS F ND1 1 
ATOM   12474 C  CD2 . HIS F 1 137 ? 43.763  14.067  31.979  1.00 27.41  ? 137 HIS F CD2 1 
ATOM   12475 C  CE1 . HIS F 1 137 ? 44.072  14.538  29.869  1.00 28.52  ? 137 HIS F CE1 1 
ATOM   12476 N  NE2 . HIS F 1 137 ? 43.977  15.103  31.065  1.00 26.84  ? 137 HIS F NE2 1 
ATOM   12477 N  N   . GLY F 1 138 ? 41.714  9.690   34.156  1.00 23.57  ? 138 GLY F N   1 
ATOM   12478 C  CA  . GLY F 1 138 ? 41.434  8.379   34.688  1.00 24.56  ? 138 GLY F CA  1 
ATOM   12479 C  C   . GLY F 1 138 ? 40.362  7.714   33.854  1.00 24.27  ? 138 GLY F C   1 
ATOM   12480 O  O   . GLY F 1 138 ? 39.544  8.400   33.282  1.00 21.59  ? 138 GLY F O   1 
ATOM   12481 N  N   . PHE F 1 139 ? 40.375  6.386   33.877  1.00 25.70  ? 139 PHE F N   1 
ATOM   12482 C  CA  . PHE F 1 139 ? 39.475  5.553   33.113  1.00 26.91  ? 139 PHE F CA  1 
ATOM   12483 C  C   . PHE F 1 139 ? 39.169  4.303   33.934  1.00 30.44  ? 139 PHE F C   1 
ATOM   12484 O  O   . PHE F 1 139 ? 40.045  3.779   34.615  1.00 32.12  ? 139 PHE F O   1 
ATOM   12485 C  CB  . PHE F 1 139 ? 40.150  5.215   31.785  1.00 25.52  ? 139 PHE F CB  1 
ATOM   12486 C  CG  . PHE F 1 139 ? 41.534  4.593   31.908  1.00 25.65  ? 139 PHE F CG  1 
ATOM   12487 C  CD1 . PHE F 1 139 ? 41.697  3.222   32.084  1.00 27.33  ? 139 PHE F CD1 1 
ATOM   12488 C  CD2 . PHE F 1 139 ? 42.674  5.398   31.849  1.00 27.42  ? 139 PHE F CD2 1 
ATOM   12489 C  CE1 . PHE F 1 139 ? 42.971  2.675   32.172  1.00 30.18  ? 139 PHE F CE1 1 
ATOM   12490 C  CE2 . PHE F 1 139 ? 43.947  4.858   31.927  1.00 27.24  ? 139 PHE F CE2 1 
ATOM   12491 C  CZ  . PHE F 1 139 ? 44.093  3.493   32.093  1.00 30.34  ? 139 PHE F CZ  1 
ATOM   12492 N  N   . LYS F 1 140 ? 37.918  3.833   33.879  1.00 36.43  ? 140 LYS F N   1 
ATOM   12493 C  CA  . LYS F 1 140 ? 37.529  2.674   34.668  1.00 43.48  ? 140 LYS F CA  1 
ATOM   12494 C  C   . LYS F 1 140 ? 37.809  1.490   33.771  1.00 33.34  ? 140 LYS F C   1 
ATOM   12495 O  O   . LYS F 1 140 ? 37.613  1.627   32.587  1.00 26.27  ? 140 LYS F O   1 
ATOM   12496 C  CB  . LYS F 1 140 ? 36.099  2.757   35.250  1.00 62.87  ? 140 LYS F CB  1 
ATOM   12497 C  CG  . LYS F 1 140 ? 35.892  2.049   36.633  1.00 76.65  ? 140 LYS F CG  1 
ATOM   12498 C  CD  . LYS F 1 140 ? 36.811  2.370   37.831  1.00 79.39  ? 140 LYS F CD  1 
ATOM   12499 C  CE  . LYS F 1 140 ? 37.042  1.277   38.893  1.00 72.26  ? 140 LYS F CE  1 
ATOM   12500 N  NZ  . LYS F 1 140 ? 36.057  1.215   39.993  1.00 56.49  ? 140 LYS F NZ  1 
ATOM   12501 N  N   . TYR F 1 141 ? 38.336  0.395   34.332  1.00 32.42  ? 141 TYR F N   1 
ATOM   12502 C  CA  . TYR F 1 141 ? 38.368  -0.901  33.669  1.00 39.54  ? 141 TYR F CA  1 
ATOM   12503 C  C   . TYR F 1 141 ? 36.963  -1.488  33.411  1.00 53.27  ? 141 TYR F C   1 
ATOM   12504 O  O   . TYR F 1 141 ? 35.921  -1.012  33.899  1.00 51.20  ? 141 TYR F O   1 
ATOM   12505 C  CB  . TYR F 1 141 ? 39.222  -1.843  34.511  1.00 44.09  ? 141 TYR F CB  1 
ATOM   12506 C  CG  . TYR F 1 141 ? 40.666  -1.857  34.045  1.00 45.30  ? 141 TYR F CG  1 
ATOM   12507 C  CD1 . TYR F 1 141 ? 41.546  -0.928  34.502  1.00 41.73  ? 141 TYR F CD1 1 
ATOM   12508 C  CD2 . TYR F 1 141 ? 41.101  -2.777  33.101  1.00 52.01  ? 141 TYR F CD2 1 
ATOM   12509 C  CE1 . TYR F 1 141 ? 42.843  -0.910  34.041  1.00 51.43  ? 141 TYR F CE1 1 
ATOM   12510 C  CE2 . TYR F 1 141 ? 42.389  -2.766  32.624  1.00 51.91  ? 141 TYR F CE2 1 
ATOM   12511 C  CZ  . TYR F 1 141 ? 43.268  -1.826  33.103  1.00 53.78  ? 141 TYR F CZ  1 
ATOM   12512 O  OH  . TYR F 1 141 ? 44.566  -1.810  32.678  1.00 65.45  ? 141 TYR F OH  1 
ATOM   12513 N  N   . PHE F 1 142 ? 36.885  -2.517  32.564  1.00 60.92  ? 142 PHE F N   1 
ATOM   12514 C  CA  . PHE F 1 142 ? 35.591  -2.711  31.937  1.00 72.92  ? 142 PHE F CA  1 
ATOM   12515 C  C   . PHE F 1 142 ? 34.721  -3.379  33.005  1.00 58.39  ? 142 PHE F C   1 
ATOM   12516 O  O   . PHE F 1 142 ? 33.513  -3.257  32.842  1.00 83.18  ? 142 PHE F O   1 
ATOM   12517 C  CB  . PHE F 1 142 ? 35.551  -3.270  30.492  1.00 84.19  ? 142 PHE F CB  1 
ATOM   12518 C  CG  . PHE F 1 142 ? 35.470  -4.783  30.459  1.00 102.77 ? 142 PHE F CG  1 
ATOM   12519 C  CD1 . PHE F 1 142 ? 36.618  -5.544  30.677  1.00 117.87 ? 142 PHE F CD1 1 
ATOM   12520 C  CD2 . PHE F 1 142 ? 34.237  -5.427  30.329  1.00 98.27  ? 142 PHE F CD2 1 
ATOM   12521 C  CE1 . PHE F 1 142 ? 36.532  -6.928  30.733  1.00 134.65 ? 142 PHE F CE1 1 
ATOM   12522 C  CE2 . PHE F 1 142 ? 34.152  -6.810  30.390  1.00 99.65  ? 142 PHE F CE2 1 
ATOM   12523 C  CZ  . PHE F 1 142 ? 35.296  -7.557  30.586  1.00 122.69 ? 142 PHE F CZ  1 
ATOM   12524 N  N   . ASP F 1 143 ? 35.261  -4.000  34.091  1.00 37.61  ? 143 ASP F N   1 
ATOM   12525 C  CA  . ASP F 1 143 ? 34.341  -4.516  35.107  1.00 33.30  ? 143 ASP F CA  1 
ATOM   12526 C  C   . ASP F 1 143 ? 34.635  -3.995  36.495  1.00 32.73  ? 143 ASP F C   1 
ATOM   12527 O  O   . ASP F 1 143 ? 34.705  -4.736  37.475  1.00 31.66  ? 143 ASP F O   1 
ATOM   12528 C  CB  . ASP F 1 143 ? 34.027  -5.995  35.056  1.00 36.35  ? 143 ASP F CB  1 
ATOM   12529 C  CG  . ASP F 1 143 ? 35.095  -6.966  35.500  1.00 40.99  ? 143 ASP F CG  1 
ATOM   12530 O  OD1 . ASP F 1 143 ? 36.240  -6.803  35.016  1.00 44.07  ? 143 ASP F OD1 1 
ATOM   12531 O  OD2 . ASP F 1 143 ? 34.718  -7.904  36.268  1.00 41.91  ? 143 ASP F OD2 1 
ATOM   12532 N  N   . GLU F 1 144 ? 34.702  -2.675  36.567  1.00 31.92  ? 144 GLU F N   1 
ATOM   12533 C  CA  . GLU F 1 144 ? 34.912  -1.954  37.813  1.00 31.74  ? 144 GLU F CA  1 
ATOM   12534 C  C   . GLU F 1 144 ? 36.197  -2.374  38.543  1.00 29.43  ? 144 GLU F C   1 
ATOM   12535 O  O   . GLU F 1 144 ? 36.286  -2.182  39.763  1.00 30.76  ? 144 GLU F O   1 
ATOM   12536 C  CB  . GLU F 1 144 ? 33.636  -2.091  38.642  1.00 32.45  ? 144 GLU F CB  1 
ATOM   12537 C  CG  . GLU F 1 144 ? 32.433  -1.391  38.015  1.00 33.77  ? 144 GLU F CG  1 
ATOM   12538 C  CD  . GLU F 1 144 ? 32.610  0.107   37.843  1.00 33.38  ? 144 GLU F CD  1 
ATOM   12539 O  OE1 . GLU F 1 144 ? 33.362  0.724   38.616  1.00 29.79  ? 144 GLU F OE1 1 
ATOM   12540 O  OE2 . GLU F 1 144 ? 32.029  0.646   36.894  1.00 36.91  ? 144 GLU F OE2 1 
ATOM   12541 N  N   . ARG F 1 145 ? 37.200  -2.853  37.785  1.00 27.71  ? 145 ARG F N   1 
ATOM   12542 C  CA  . ARG F 1 145 ? 38.489  -3.269  38.334  1.00 31.66  ? 145 ARG F CA  1 
ATOM   12543 C  C   . ARG F 1 145 ? 39.459  -2.095  38.460  1.00 30.67  ? 145 ARG F C   1 
ATOM   12544 O  O   . ARG F 1 145 ? 39.283  -1.062  37.798  1.00 35.74  ? 145 ARG F O   1 
ATOM   12545 C  CB  . ARG F 1 145 ? 39.055  -4.441  37.527  1.00 32.92  ? 145 ARG F CB  1 
ATOM   12546 C  CG  . ARG F 1 145 ? 38.109  -5.621  37.703  1.00 31.26  ? 145 ARG F CG  1 
ATOM   12547 C  CD  . ARG F 1 145 ? 38.762  -6.936  37.517  1.00 32.01  ? 145 ARG F CD  1 
ATOM   12548 N  NE  . ARG F 1 145 ? 37.759  -7.989  37.617  1.00 33.24  ? 145 ARG F NE  1 
ATOM   12549 C  CZ  . ARG F 1 145 ? 37.543  -8.803  38.659  1.00 35.73  ? 145 ARG F CZ  1 
ATOM   12550 N  NH1 . ARG F 1 145 ? 38.402  -8.937  39.658  1.00 42.39  ? 145 ARG F NH1 1 
ATOM   12551 N  NH2 . ARG F 1 145 ? 36.440  -9.523  38.680  1.00 34.21  ? 145 ARG F NH2 1 
ATOM   12552 N  N   . ASP F 1 146 ? 40.387  -2.213  39.421  1.00 28.64  ? 146 ASP F N   1 
ATOM   12553 C  CA  . ASP F 1 146 ? 41.459  -1.237  39.549  1.00 31.36  ? 146 ASP F CA  1 
ATOM   12554 C  C   . ASP F 1 146 ? 42.697  -1.873  38.940  1.00 31.80  ? 146 ASP F C   1 
ATOM   12555 O  O   . ASP F 1 146 ? 42.671  -3.001  38.399  1.00 22.50  ? 146 ASP F O   1 
ATOM   12556 C  CB  . ASP F 1 146 ? 41.653  -0.692  40.958  1.00 32.65  ? 146 ASP F CB  1 
ATOM   12557 C  CG  . ASP F 1 146 ? 41.924  -1.773  41.996  1.00 30.23  ? 146 ASP F CG  1 
ATOM   12558 O  OD1 . ASP F 1 146 ? 42.482  -2.808  41.611  1.00 24.86  ? 146 ASP F OD1 1 
ATOM   12559 O  OD2 . ASP F 1 146 ? 41.504  -1.604  43.153  1.00 29.46  ? 146 ASP F OD2 1 
ATOM   12560 N  N   . MET F 1 147 ? 43.761  -1.080  39.010  1.00 31.76  ? 147 MET F N   1 
ATOM   12561 C  CA  . MET F 1 147 ? 45.033  -1.471  38.439  1.00 32.96  ? 147 MET F CA  1 
ATOM   12562 C  C   . MET F 1 147 ? 45.602  -2.755  39.089  1.00 27.16  ? 147 MET F C   1 
ATOM   12563 O  O   . MET F 1 147 ? 46.367  -3.454  38.477  1.00 25.40  ? 147 MET F O   1 
ATOM   12564 C  CB  . MET F 1 147 ? 45.901  -0.213  38.541  1.00 38.81  ? 147 MET F CB  1 
ATOM   12565 C  CG  . MET F 1 147 ? 47.037  -0.162  37.591  1.00 39.58  ? 147 MET F CG  1 
ATOM   12566 S  SD  . MET F 1 147 ? 46.395  -0.253  35.923  1.00 39.02  ? 147 MET F SD  1 
ATOM   12567 C  CE  . MET F 1 147 ? 46.374  1.427   35.311  1.00 45.43  ? 147 MET F CE  1 
ATOM   12568 N  N   . LEU F 1 148 ? 45.216  -3.154  40.300  1.00 26.77  ? 148 LEU F N   1 
ATOM   12569 C  CA  . LEU F 1 148 ? 45.686  -4.410  40.879  1.00 26.34  ? 148 LEU F CA  1 
ATOM   12570 C  C   . LEU F 1 148 ? 44.808  -5.582  40.462  1.00 28.18  ? 148 LEU F C   1 
ATOM   12571 O  O   . LEU F 1 148 ? 45.057  -6.699  40.931  1.00 29.14  ? 148 LEU F O   1 
ATOM   12572 C  CB  . LEU F 1 148 ? 45.693  -4.321  42.407  1.00 28.48  ? 148 LEU F CB  1 
ATOM   12573 C  CG  . LEU F 1 148 ? 46.546  -3.195  43.012  1.00 31.68  ? 148 LEU F CG  1 
ATOM   12574 C  CD1 . LEU F 1 148 ? 46.322  -3.145  44.498  1.00 31.03  ? 148 LEU F CD1 1 
ATOM   12575 C  CD2 . LEU F 1 148 ? 48.025  -3.359  42.693  1.00 33.63  ? 148 LEU F CD2 1 
ATOM   12576 N  N   . GLY F 1 149 ? 43.730  -5.327  39.689  1.00 25.55  ? 149 GLY F N   1 
ATOM   12577 C  CA  . GLY F 1 149 ? 42.915  -6.421  39.172  1.00 26.04  ? 149 GLY F CA  1 
ATOM   12578 C  C   . GLY F 1 149 ? 41.751  -6.860  40.071  1.00 26.60  ? 149 GLY F C   1 
ATOM   12579 O  O   . GLY F 1 149 ? 41.074  -7.868  39.853  1.00 22.84  ? 149 GLY F O   1 
ATOM   12580 N  N   . PHE F 1 150 ? 41.475  -6.054  41.081  1.00 29.84  ? 150 PHE F N   1 
ATOM   12581 C  CA  . PHE F 1 150 ? 40.391  -6.330  42.008  1.00 31.42  ? 150 PHE F CA  1 
ATOM   12582 C  C   . PHE F 1 150 ? 39.252  -5.393  41.689  1.00 28.51  ? 150 PHE F C   1 
ATOM   12583 O  O   . PHE F 1 150 ? 39.528  -4.252  41.342  1.00 24.08  ? 150 PHE F O   1 
ATOM   12584 C  CB  . PHE F 1 150 ? 40.867  -6.105  43.445  1.00 30.52  ? 150 PHE F CB  1 
ATOM   12585 C  CG  . PHE F 1 150 ? 41.586  -7.346  43.928  1.00 30.06  ? 150 PHE F CG  1 
ATOM   12586 C  CD1 . PHE F 1 150 ? 42.844  -7.668  43.442  1.00 31.34  ? 150 PHE F CD1 1 
ATOM   12587 C  CD2 . PHE F 1 150 ? 40.950  -8.240  44.781  1.00 32.73  ? 150 PHE F CD2 1 
ATOM   12588 C  CE1 . PHE F 1 150 ? 43.473  -8.837  43.857  1.00 31.36  ? 150 PHE F CE1 1 
ATOM   12589 C  CE2 . PHE F 1 150 ? 41.590  -9.397  45.206  1.00 29.13  ? 150 PHE F CE2 1 
ATOM   12590 C  CZ  . PHE F 1 150 ? 42.861  -9.683  44.754  1.00 30.37  ? 150 PHE F CZ  1 
ATOM   12591 N  N   . VAL F 1 151 ? 38.020  -5.855  41.905  1.00 26.50  ? 151 VAL F N   1 
ATOM   12592 C  CA  . VAL F 1 151 ? 36.895  -4.943  41.801  1.00 26.09  ? 151 VAL F CA  1 
ATOM   12593 C  C   . VAL F 1 151 ? 36.994  -3.912  42.936  1.00 28.67  ? 151 VAL F C   1 
ATOM   12594 O  O   . VAL F 1 151 ? 37.282  -4.271  44.088  1.00 31.57  ? 151 VAL F O   1 
ATOM   12595 C  CB  . VAL F 1 151 ? 35.561  -5.710  41.867  1.00 27.01  ? 151 VAL F CB  1 
ATOM   12596 C  CG1 . VAL F 1 151 ? 34.365  -4.779  41.818  1.00 26.56  ? 151 VAL F CG1 1 
ATOM   12597 C  CG2 . VAL F 1 151 ? 35.457  -6.792  40.815  1.00 27.91  ? 151 VAL F CG2 1 
ATOM   12598 N  N   . ASP F 1 152 ? 36.666  -2.654  42.603  1.00 31.10  ? 152 ASP F N   1 
ATOM   12599 C  CA  . ASP F 1 152 ? 36.973  -1.490  43.419  1.00 32.18  ? 152 ASP F CA  1 
ATOM   12600 C  C   . ASP F 1 152 ? 35.704  -0.659  43.449  1.00 30.54  ? 152 ASP F C   1 
ATOM   12601 O  O   . ASP F 1 152 ? 35.248  -0.248  42.384  1.00 31.71  ? 152 ASP F O   1 
ATOM   12602 C  CB  . ASP F 1 152 ? 38.152  -0.732  42.825  1.00 32.41  ? 152 ASP F CB  1 
ATOM   12603 C  CG  . ASP F 1 152 ? 38.748  0.397   43.653  1.00 37.21  ? 152 ASP F CG  1 
ATOM   12604 O  OD1 . ASP F 1 152 ? 37.897  1.162   44.180  1.00 31.46  ? 152 ASP F OD1 1 
ATOM   12605 O  OD2 . ASP F 1 152 ? 40.052  0.537   43.674  1.00 33.59  ? 152 ASP F OD2 1 
ATOM   12606 N  N   . GLY F 1 153 ? 35.111  -0.509  44.643  1.00 29.32  ? 153 GLY F N   1 
ATOM   12607 C  CA  . GLY F 1 153 ? 33.868  0.244   44.800  1.00 29.41  ? 153 GLY F CA  1 
ATOM   12608 C  C   . GLY F 1 153 ? 32.740  -0.539  45.491  1.00 26.78  ? 153 GLY F C   1 
ATOM   12609 O  O   . GLY F 1 153 ? 31.790  0.075   45.945  1.00 24.83  ? 153 GLY F O   1 
ATOM   12610 N  N   . THR F 1 154 ? 32.873  -1.865  45.600  1.00 24.33  ? 154 THR F N   1 
ATOM   12611 C  CA  . THR F 1 154 ? 31.825  -2.765  46.041  1.00 24.55  ? 154 THR F CA  1 
ATOM   12612 C  C   . THR F 1 154 ? 31.134  -2.298  47.327  1.00 26.63  ? 154 THR F C   1 
ATOM   12613 O  O   . THR F 1 154 ? 29.913  -2.336  47.453  1.00 26.13  ? 154 THR F O   1 
ATOM   12614 C  CB  . THR F 1 154 ? 32.462  -4.106  46.330  1.00 23.20  ? 154 THR F CB  1 
ATOM   12615 O  OG1 . THR F 1 154 ? 33.115  -4.432  45.127  1.00 23.93  ? 154 THR F OG1 1 
ATOM   12616 C  CG2 . THR F 1 154 ? 31.420  -5.159  46.560  1.00 23.97  ? 154 THR F CG2 1 
ATOM   12617 N  N   . GLU F 1 155 ? 31.908  -1.901  48.321  1.00 27.01  ? 155 GLU F N   1 
ATOM   12618 C  CA  . GLU F 1 155 ? 31.310  -1.653  49.612  1.00 25.15  ? 155 GLU F CA  1 
ATOM   12619 C  C   . GLU F 1 155 ? 30.989  -0.177  49.758  1.00 22.86  ? 155 GLU F C   1 
ATOM   12620 O  O   . GLU F 1 155 ? 30.644  0.234   50.848  1.00 25.03  ? 155 GLU F O   1 
ATOM   12621 C  CB  . GLU F 1 155 ? 32.175  -2.187  50.754  1.00 25.56  ? 155 GLU F CB  1 
ATOM   12622 C  CG  . GLU F 1 155 ? 32.167  -3.706  50.878  1.00 27.88  ? 155 GLU F CG  1 
ATOM   12623 C  CD  . GLU F 1 155 ? 30.814  -4.256  51.224  1.00 31.83  ? 155 GLU F CD  1 
ATOM   12624 O  OE1 . GLU F 1 155 ? 30.265  -3.823  52.258  1.00 36.70  ? 155 GLU F OE1 1 
ATOM   12625 O  OE2 . GLU F 1 155 ? 30.323  -5.130  50.484  1.00 40.19  ? 155 GLU F OE2 1 
ATOM   12626 N  N   . ASN F 1 156 ? 31.057  0.637   48.709  1.00 22.34  ? 156 ASN F N   1 
ATOM   12627 C  CA  . ASN F 1 156 ? 30.688  2.016   48.935  1.00 26.17  ? 156 ASN F CA  1 
ATOM   12628 C  C   . ASN F 1 156 ? 29.272  2.068   49.482  1.00 28.75  ? 156 ASN F C   1 
ATOM   12629 O  O   . ASN F 1 156 ? 28.500  1.187   49.161  1.00 32.61  ? 156 ASN F O   1 
ATOM   12630 C  CB  . ASN F 1 156 ? 30.679  2.861   47.681  1.00 27.15  ? 156 ASN F CB  1 
ATOM   12631 C  CG  . ASN F 1 156 ? 32.013  3.500   47.460  1.00 30.43  ? 156 ASN F CG  1 
ATOM   12632 O  OD1 . ASN F 1 156 ? 32.687  3.913   48.424  1.00 29.76  ? 156 ASN F OD1 1 
ATOM   12633 N  ND2 . ASN F 1 156 ? 32.392  3.553   46.191  1.00 29.51  ? 156 ASN F ND2 1 
ATOM   12634 N  N   . PRO F 1 157 ? 28.876  3.082   50.288  1.00 27.21  ? 157 PRO F N   1 
ATOM   12635 C  CA  . PRO F 1 157 ? 27.469  3.283   50.628  1.00 26.97  ? 157 PRO F CA  1 
ATOM   12636 C  C   . PRO F 1 157 ? 26.619  3.769   49.469  1.00 29.08  ? 157 PRO F C   1 
ATOM   12637 O  O   . PRO F 1 157 ? 27.126  4.351   48.528  1.00 31.71  ? 157 PRO F O   1 
ATOM   12638 C  CB  . PRO F 1 157 ? 27.529  4.328   51.757  1.00 26.71  ? 157 PRO F CB  1 
ATOM   12639 C  CG  . PRO F 1 157 ? 28.780  5.081   51.437  1.00 26.04  ? 157 PRO F CG  1 
ATOM   12640 C  CD  . PRO F 1 157 ? 29.765  4.034   50.957  1.00 27.04  ? 157 PRO F CD  1 
ATOM   12641 N  N   . THR F 1 158 ? 25.312  3.611   49.640  1.00 36.22  ? 158 THR F N   1 
ATOM   12642 C  CA  . THR F 1 158 ? 24.280  3.874   48.652  1.00 38.05  ? 158 THR F CA  1 
ATOM   12643 C  C   . THR F 1 158 ? 23.193  4.744   49.245  1.00 37.02  ? 158 THR F C   1 
ATOM   12644 O  O   . THR F 1 158 ? 22.899  4.563   50.418  1.00 39.84  ? 158 THR F O   1 
ATOM   12645 C  CB  . THR F 1 158 ? 23.629  2.528   48.373  1.00 37.52  ? 158 THR F CB  1 
ATOM   12646 O  OG1 . THR F 1 158 ? 24.693  2.073   47.570  1.00 38.35  ? 158 THR F OG1 1 
ATOM   12647 C  CG2 . THR F 1 158 ? 22.316  2.588   47.620  1.00 41.26  ? 158 THR F CG2 1 
ATOM   12648 N  N   . GLY F 1 159 ? 22.553  5.564   48.399  1.00 36.08  ? 159 GLY F N   1 
ATOM   12649 C  CA  . GLY F 1 159 ? 21.334  6.286   48.735  1.00 38.80  ? 159 GLY F CA  1 
ATOM   12650 C  C   . GLY F 1 159 ? 21.409  6.974   50.100  1.00 42.62  ? 159 GLY F C   1 
ATOM   12651 O  O   . GLY F 1 159 ? 22.340  7.707   50.369  1.00 39.62  ? 159 GLY F O   1 
ATOM   12652 N  N   . ALA F 1 160 ? 20.423  6.727   50.969  1.00 48.74  ? 160 ALA F N   1 
ATOM   12653 C  CA  . ALA F 1 160 ? 20.326  7.457   52.214  1.00 45.94  ? 160 ALA F CA  1 
ATOM   12654 C  C   . ALA F 1 160 ? 21.611  7.233   53.021  1.00 43.48  ? 160 ALA F C   1 
ATOM   12655 O  O   . ALA F 1 160 ? 22.160  8.176   53.577  1.00 36.63  ? 160 ALA F O   1 
ATOM   12656 C  CB  . ALA F 1 160 ? 19.060  7.061   52.943  1.00 43.51  ? 160 ALA F CB  1 
ATOM   12657 N  N   . ALA F 1 161 ? 22.161  6.009   53.024  1.00 45.85  ? 161 ALA F N   1 
ATOM   12658 C  CA  . ALA F 1 161 ? 23.350  5.726   53.828  1.00 46.02  ? 161 ALA F CA  1 
ATOM   12659 C  C   . ALA F 1 161 ? 24.509  6.615   53.382  1.00 44.67  ? 161 ALA F C   1 
ATOM   12660 O  O   . ALA F 1 161 ? 25.288  7.102   54.198  1.00 39.69  ? 161 ALA F O   1 
ATOM   12661 C  CB  . ALA F 1 161 ? 23.751  4.269   53.726  1.00 42.46  ? 161 ALA F CB  1 
ATOM   12662 N  N   . ALA F 1 162 ? 24.585  6.821   52.063  1.00 38.48  ? 162 ALA F N   1 
ATOM   12663 C  CA  . ALA F 1 162 ? 25.637  7.610   51.479  1.00 36.23  ? 162 ALA F CA  1 
ATOM   12664 C  C   . ALA F 1 162 ? 25.440  9.083   51.800  1.00 30.31  ? 162 ALA F C   1 
ATOM   12665 O  O   . ALA F 1 162 ? 26.424  9.682   52.190  1.00 26.05  ? 162 ALA F O   1 
ATOM   12666 C  CB  . ALA F 1 162 ? 25.677  7.352   50.028  1.00 34.89  ? 162 ALA F CB  1 
ATOM   12667 N  N   . ARG F 1 163 ? 24.213  9.610   51.609  1.00 34.99  ? 163 ARG F N   1 
ATOM   12668 C  CA  . ARG F 1 163 ? 23.827  10.991  51.951  1.00 41.49  ? 163 ARG F CA  1 
ATOM   12669 C  C   . ARG F 1 163 ? 24.318  11.255  53.389  1.00 42.21  ? 163 ARG F C   1 
ATOM   12670 O  O   . ARG F 1 163 ? 24.959  12.272  53.652  1.00 46.65  ? 163 ARG F O   1 
ATOM   12671 C  CB  . ARG F 1 163 ? 22.343  11.432  51.734  1.00 40.03  ? 163 ARG F CB  1 
ATOM   12672 C  CG  . ARG F 1 163 ? 21.714  11.753  50.374  1.00 33.06  ? 163 ARG F CG  1 
ATOM   12673 N  N   . ARG F 1 164 ? 24.112  10.313  54.318  1.00 38.42  ? 164 ARG F N   1 
ATOM   12674 C  CA  . ARG F 1 164 ? 24.434  10.561  55.709  1.00 42.86  ? 164 ARG F CA  1 
ATOM   12675 C  C   . ARG F 1 164 ? 25.926  10.464  55.967  1.00 37.01  ? 164 ARG F C   1 
ATOM   12676 O  O   . ARG F 1 164 ? 26.416  11.177  56.808  1.00 40.39  ? 164 ARG F O   1 
ATOM   12677 C  CB  . ARG F 1 164 ? 23.690  9.658   56.698  1.00 59.85  ? 164 ARG F CB  1 
ATOM   12678 C  CG  . ARG F 1 164 ? 22.458  10.321  57.316  1.00 84.99  ? 164 ARG F CG  1 
ATOM   12679 C  CD  . ARG F 1 164 ? 21.423  9.339   57.908  1.00 99.93  ? 164 ARG F CD  1 
ATOM   12680 N  NE  . ARG F 1 164 ? 22.111  8.271   58.650  1.00 108.49 ? 164 ARG F NE  1 
ATOM   12681 C  CZ  . ARG F 1 164 ? 22.160  6.977   58.325  1.00 96.60  ? 164 ARG F CZ  1 
ATOM   12682 N  NH1 . ARG F 1 164 ? 23.089  6.199   58.867  1.00 90.41  ? 164 ARG F NH1 1 
ATOM   12683 N  NH2 . ARG F 1 164 ? 21.348  6.492   57.396  1.00 84.23  ? 164 ARG F NH2 1 
ATOM   12684 N  N   . ALA F 1 165 ? 26.659  9.620   55.250  1.00 32.27  ? 165 ALA F N   1 
ATOM   12685 C  CA  . ALA F 1 165 ? 28.069  9.445   55.531  1.00 28.14  ? 165 ALA F CA  1 
ATOM   12686 C  C   . ALA F 1 165 ? 28.915  10.575  54.940  1.00 25.36  ? 165 ALA F C   1 
ATOM   12687 O  O   . ALA F 1 165 ? 30.009  10.782  55.408  1.00 25.25  ? 165 ALA F O   1 
ATOM   12688 C  CB  . ALA F 1 165 ? 28.516  8.114   55.007  1.00 27.29  ? 165 ALA F CB  1 
ATOM   12689 N  N   . VAL F 1 166 ? 28.395  11.326  53.962  1.00 29.25  ? 166 VAL F N   1 
ATOM   12690 C  CA  . VAL F 1 166 ? 29.155  12.222  53.085  1.00 26.95  ? 166 VAL F CA  1 
ATOM   12691 C  C   . VAL F 1 166 ? 28.852  13.703  53.334  1.00 28.52  ? 166 VAL F C   1 
ATOM   12692 O  O   . VAL F 1 166 ? 29.743  14.537  53.202  1.00 29.78  ? 166 VAL F O   1 
ATOM   12693 C  CB  . VAL F 1 166 ? 28.775  11.834  51.636  1.00 27.29  ? 166 VAL F CB  1 
ATOM   12694 C  CG1 . VAL F 1 166 ? 28.739  13.015  50.673  1.00 28.54  ? 166 VAL F CG1 1 
ATOM   12695 C  CG2 . VAL F 1 166 ? 29.612  10.668  51.130  1.00 24.88  ? 166 VAL F CG2 1 
ATOM   12696 N  N   . LEU F 1 167 ? 27.591  14.047  53.608  1.00 26.41  ? 167 LEU F N   1 
ATOM   12697 C  CA  . LEU F 1 167 ? 27.191  15.445  53.597  1.00 31.13  ? 167 LEU F CA  1 
ATOM   12698 C  C   . LEU F 1 167 ? 27.168  16.024  55.006  1.00 33.51  ? 167 LEU F C   1 
ATOM   12699 O  O   . LEU F 1 167 ? 26.593  15.437  55.918  1.00 35.23  ? 167 LEU F O   1 
ATOM   12700 C  CB  . LEU F 1 167 ? 25.822  15.593  52.937  1.00 30.91  ? 167 LEU F CB  1 
ATOM   12701 C  CG  . LEU F 1 167 ? 25.755  15.253  51.445  1.00 30.34  ? 167 LEU F CG  1 
ATOM   12702 C  CD1 . LEU F 1 167 ? 24.357  15.421  50.912  1.00 29.02  ? 167 LEU F CD1 1 
ATOM   12703 C  CD2 . LEU F 1 167 ? 26.711  16.144  50.651  1.00 32.13  ? 167 LEU F CD2 1 
ATOM   12704 N  N   . VAL F 1 168 ? 27.800  17.191  55.153  1.00 32.02  ? 168 VAL F N   1 
ATOM   12705 C  CA  . VAL F 1 168 ? 27.759  17.947  56.383  1.00 29.48  ? 168 VAL F CA  1 
ATOM   12706 C  C   . VAL F 1 168 ? 26.301  18.283  56.634  1.00 32.43  ? 168 VAL F C   1 
ATOM   12707 O  O   . VAL F 1 168 ? 25.617  18.695  55.695  1.00 29.91  ? 168 VAL F O   1 
ATOM   12708 C  CB  . VAL F 1 168 ? 28.624  19.211  56.269  1.00 28.20  ? 168 VAL F CB  1 
ATOM   12709 C  CG1 . VAL F 1 168 ? 28.439  20.167  57.449  1.00 24.42  ? 168 VAL F CG1 1 
ATOM   12710 C  CG2 . VAL F 1 168 ? 30.091  18.828  56.073  1.00 30.70  ? 168 VAL F CG2 1 
ATOM   12711 N  N   . GLY F 1 169 ? 25.866  18.104  57.895  1.00 35.80  ? 169 GLY F N   1 
ATOM   12712 C  CA  . GLY F 1 169 ? 24.542  18.501  58.345  1.00 39.06  ? 169 GLY F CA  1 
ATOM   12713 C  C   . GLY F 1 169 ? 24.577  19.571  59.453  1.00 47.18  ? 169 GLY F C   1 
ATOM   12714 O  O   . GLY F 1 169 ? 25.307  20.579  59.379  1.00 47.05  ? 169 GLY F O   1 
ATOM   12715 N  N   . ALA F 1 170 ? 23.719  19.356  60.475  1.00 57.26  ? 170 ALA F N   1 
ATOM   12716 C  CA  . ALA F 1 170 ? 23.419  20.349  61.509  1.00 47.59  ? 170 ALA F CA  1 
ATOM   12717 C  C   . ALA F 1 170 ? 24.610  20.541  62.457  1.00 42.69  ? 170 ALA F C   1 
ATOM   12718 O  O   . ALA F 1 170 ? 24.688  21.570  63.102  1.00 45.46  ? 170 ALA F O   1 
ATOM   12719 C  CB  . ALA F 1 170 ? 22.171  19.947  62.233  1.00 41.43  ? 170 ALA F CB  1 
ATOM   12720 N  N   . GLU F 1 171 ? 25.588  19.625  62.456  1.00 39.47  ? 171 GLU F N   1 
ATOM   12721 C  CA  . GLU F 1 171 ? 26.799  19.756  63.256  1.00 39.53  ? 171 GLU F CA  1 
ATOM   12722 C  C   . GLU F 1 171 ? 27.690  20.896  62.759  1.00 36.13  ? 171 GLU F C   1 
ATOM   12723 O  O   . GLU F 1 171 ? 28.681  21.161  63.427  1.00 38.46  ? 171 GLU F O   1 
ATOM   12724 C  CB  . GLU F 1 171 ? 27.638  18.465  63.355  1.00 38.71  ? 171 GLU F CB  1 
ATOM   12725 C  CG  . GLU F 1 171 ? 28.471  18.073  62.131  1.00 38.47  ? 171 GLU F CG  1 
ATOM   12726 C  CD  . GLU F 1 171 ? 27.783  17.589  60.859  1.00 41.84  ? 171 GLU F CD  1 
ATOM   12727 O  OE1 . GLU F 1 171 ? 26.546  17.553  60.845  1.00 43.86  ? 171 GLU F OE1 1 
ATOM   12728 O  OE2 . GLU F 1 171 ? 28.463  17.248  59.851  1.00 48.05  ? 171 GLU F OE2 1 
ATOM   12729 N  N   . ASP F 1 172 ? 27.428  21.465  61.570  1.00 33.60  ? 172 ASP F N   1 
ATOM   12730 C  CA  . ASP F 1 172 ? 28.177  22.624  61.090  1.00 36.54  ? 172 ASP F CA  1 
ATOM   12731 C  C   . ASP F 1 172 ? 27.280  23.401  60.140  1.00 38.79  ? 172 ASP F C   1 
ATOM   12732 O  O   . ASP F 1 172 ? 27.539  23.519  58.956  1.00 40.23  ? 172 ASP F O   1 
ATOM   12733 C  CB  . ASP F 1 172 ? 29.511  22.287  60.428  1.00 39.80  ? 172 ASP F CB  1 
ATOM   12734 C  CG  . ASP F 1 172 ? 30.489  23.450  60.284  1.00 35.95  ? 172 ASP F CG  1 
ATOM   12735 O  OD1 . ASP F 1 172 ? 30.052  24.572  60.609  1.00 36.58  ? 172 ASP F OD1 1 
ATOM   12736 O  OD2 . ASP F 1 172 ? 31.665  23.219  59.864  1.00 31.70  ? 172 ASP F OD2 1 
ATOM   12737 N  N   . PRO F 1 173 ? 26.187  23.956  60.664  1.00 47.20  ? 173 PRO F N   1 
ATOM   12738 C  CA  . PRO F 1 173 ? 25.033  24.324  59.836  1.00 47.36  ? 173 PRO F CA  1 
ATOM   12739 C  C   . PRO F 1 173 ? 25.280  25.390  58.773  1.00 38.81  ? 173 PRO F C   1 
ATOM   12740 O  O   . PRO F 1 173 ? 24.617  25.428  57.745  1.00 33.99  ? 173 PRO F O   1 
ATOM   12741 C  CB  . PRO F 1 173 ? 23.983  24.782  60.854  1.00 51.69  ? 173 PRO F CB  1 
ATOM   12742 C  CG  . PRO F 1 173 ? 24.775  25.057  62.120  1.00 54.24  ? 173 PRO F CG  1 
ATOM   12743 C  CD  . PRO F 1 173 ? 26.032  24.235  62.095  1.00 48.88  ? 173 PRO F CD  1 
ATOM   12744 N  N   . ALA F 1 174 ? 26.275  26.237  58.977  1.00 38.12  ? 174 ALA F N   1 
ATOM   12745 C  CA  . ALA F 1 174 ? 26.603  27.171  57.912  1.00 37.38  ? 174 ALA F CA  1 
ATOM   12746 C  C   . ALA F 1 174 ? 27.115  26.443  56.646  1.00 39.09  ? 174 ALA F C   1 
ATOM   12747 O  O   . ALA F 1 174 ? 27.118  26.998  55.545  1.00 44.11  ? 174 ALA F O   1 
ATOM   12748 C  CB  . ALA F 1 174 ? 27.612  28.149  58.460  1.00 35.71  ? 174 ALA F CB  1 
ATOM   12749 N  N   . PHE F 1 175 ? 27.572  25.186  56.768  1.00 35.33  ? 175 PHE F N   1 
ATOM   12750 C  CA  . PHE F 1 175 ? 28.252  24.497  55.674  1.00 35.83  ? 175 PHE F CA  1 
ATOM   12751 C  C   . PHE F 1 175 ? 27.542  23.194  55.295  1.00 35.77  ? 175 PHE F C   1 
ATOM   12752 O  O   . PHE F 1 175 ? 28.056  22.418  54.513  1.00 32.94  ? 175 PHE F O   1 
ATOM   12753 C  CB  . PHE F 1 175 ? 29.702  24.262  56.111  1.00 36.50  ? 175 PHE F CB  1 
ATOM   12754 C  CG  . PHE F 1 175 ? 30.466  25.568  56.247  1.00 38.45  ? 175 PHE F CG  1 
ATOM   12755 C  CD1 . PHE F 1 175 ? 30.697  26.364  55.139  1.00 36.92  ? 175 PHE F CD1 1 
ATOM   12756 C  CD2 . PHE F 1 175 ? 30.931  26.002  57.480  1.00 40.27  ? 175 PHE F CD2 1 
ATOM   12757 C  CE1 . PHE F 1 175 ? 31.373  27.555  55.261  1.00 38.12  ? 175 PHE F CE1 1 
ATOM   12758 C  CE2 . PHE F 1 175 ? 31.594  27.213  57.603  1.00 40.88  ? 175 PHE F CE2 1 
ATOM   12759 C  CZ  . PHE F 1 175 ? 31.801  27.988  56.496  1.00 41.60  ? 175 PHE F CZ  1 
ATOM   12760 N  N   . ALA F 1 176 ? 26.348  22.963  55.835  1.00 31.79  ? 176 ALA F N   1 
ATOM   12761 C  CA  . ALA F 1 176 ? 25.518  21.847  55.441  1.00 29.84  ? 176 ALA F CA  1 
ATOM   12762 C  C   . ALA F 1 176 ? 25.427  21.722  53.930  1.00 28.72  ? 176 ALA F C   1 
ATOM   12763 O  O   . ALA F 1 176 ? 25.183  22.710  53.254  1.00 33.45  ? 176 ALA F O   1 
ATOM   12764 C  CB  . ALA F 1 176 ? 24.164  22.100  56.015  1.00 31.17  ? 176 ALA F CB  1 
ATOM   12765 N  N   . GLY F 1 177 ? 25.620  20.502  53.399  1.00 32.16  ? 177 GLY F N   1 
ATOM   12766 C  CA  . GLY F 1 177 ? 25.625  20.266  51.948  1.00 33.24  ? 177 GLY F CA  1 
ATOM   12767 C  C   . GLY F 1 177 ? 27.039  20.143  51.370  1.00 32.14  ? 177 GLY F C   1 
ATOM   12768 O  O   . GLY F 1 177 ? 27.275  19.820  50.192  1.00 44.44  ? 177 GLY F O   1 
ATOM   12769 N  N   . GLY F 1 178 ? 27.992  20.477  52.227  1.00 30.22  ? 178 GLY F N   1 
ATOM   12770 C  CA  . GLY F 1 178 ? 29.396  20.348  51.901  1.00 29.43  ? 178 GLY F CA  1 
ATOM   12771 C  C   . GLY F 1 178 ? 29.899  18.947  52.208  1.00 27.90  ? 178 GLY F C   1 
ATOM   12772 O  O   . GLY F 1 178 ? 29.155  18.090  52.675  1.00 30.00  ? 178 GLY F O   1 
ATOM   12773 N  N   . SER F 1 179 ? 31.160  18.714  51.869  1.00 26.69  ? 179 SER F N   1 
ATOM   12774 C  CA  . SER F 1 179 ? 31.787  17.441  52.141  1.00 26.90  ? 179 SER F CA  1 
ATOM   12775 C  C   . SER F 1 179 ? 33.303  17.643  52.213  1.00 27.43  ? 179 SER F C   1 
ATOM   12776 O  O   . SER F 1 179 ? 33.802  18.713  51.853  1.00 29.08  ? 179 SER F O   1 
ATOM   12777 C  CB  . SER F 1 179 ? 31.362  16.420  51.087  1.00 25.51  ? 179 SER F CB  1 
ATOM   12778 O  OG  . SER F 1 179 ? 31.839  15.136  51.470  1.00 26.70  ? 179 SER F OG  1 
ATOM   12779 N  N   . TYR F 1 180 ? 34.013  16.634  52.730  1.00 25.76  ? 180 TYR F N   1 
ATOM   12780 C  CA  . TYR F 1 180 ? 35.454  16.686  52.797  1.00 26.30  ? 180 TYR F CA  1 
ATOM   12781 C  C   . TYR F 1 180 ? 36.029  15.601  51.899  1.00 24.80  ? 180 TYR F C   1 
ATOM   12782 O  O   . TYR F 1 180 ? 35.750  14.413  52.064  1.00 24.33  ? 180 TYR F O   1 
ATOM   12783 C  CB  . TYR F 1 180 ? 35.985  16.550  54.229  1.00 27.14  ? 180 TYR F CB  1 
ATOM   12784 C  CG  . TYR F 1 180 ? 35.594  17.711  55.131  1.00 28.18  ? 180 TYR F CG  1 
ATOM   12785 C  CD1 . TYR F 1 180 ? 34.378  17.690  55.798  1.00 28.93  ? 180 TYR F CD1 1 
ATOM   12786 C  CD2 . TYR F 1 180 ? 36.429  18.804  55.336  1.00 25.92  ? 180 TYR F CD2 1 
ATOM   12787 C  CE1 . TYR F 1 180 ? 33.976  18.731  56.615  1.00 29.70  ? 180 TYR F CE1 1 
ATOM   12788 C  CE2 . TYR F 1 180 ? 36.043  19.846  56.165  1.00 26.79  ? 180 TYR F CE2 1 
ATOM   12789 C  CZ  . TYR F 1 180 ? 34.817  19.815  56.816  1.00 29.41  ? 180 TYR F CZ  1 
ATOM   12790 O  OH  . TYR F 1 180 ? 34.345  20.803  57.676  1.00 31.43  ? 180 TYR F OH  1 
ATOM   12791 N  N   . ALA F 1 181 ? 36.934  16.053  51.030  1.00 26.11  ? 181 ALA F N   1 
ATOM   12792 C  CA  . ALA F 1 181 ? 37.619  15.181  50.093  1.00 30.97  ? 181 ALA F CA  1 
ATOM   12793 C  C   . ALA F 1 181 ? 39.102  15.087  50.416  1.00 29.68  ? 181 ALA F C   1 
ATOM   12794 O  O   . ALA F 1 181 ? 39.781  16.092  50.518  1.00 28.69  ? 181 ALA F O   1 
ATOM   12795 C  CB  . ALA F 1 181 ? 37.455  15.701  48.681  1.00 29.96  ? 181 ALA F CB  1 
ATOM   12796 N  N   . VAL F 1 182 ? 39.590  13.853  50.470  1.00 30.83  ? 182 VAL F N   1 
ATOM   12797 C  CA  . VAL F 1 182 ? 41.007  13.548  50.537  1.00 29.33  ? 182 VAL F CA  1 
ATOM   12798 C  C   . VAL F 1 182 ? 41.399  12.906  49.223  1.00 28.20  ? 182 VAL F C   1 
ATOM   12799 O  O   . VAL F 1 182 ? 40.754  11.968  48.769  1.00 25.26  ? 182 VAL F O   1 
ATOM   12800 C  CB  . VAL F 1 182 ? 41.292  12.564  51.679  1.00 31.09  ? 182 VAL F CB  1 
ATOM   12801 C  CG1 . VAL F 1 182 ? 42.694  11.961  51.626  1.00 32.76  ? 182 VAL F CG1 1 
ATOM   12802 C  CG2 . VAL F 1 182 ? 40.947  13.181  53.032  1.00 33.11  ? 182 VAL F CG2 1 
ATOM   12803 N  N   . VAL F 1 183 ? 42.497  13.396  48.663  1.00 28.65  ? 183 VAL F N   1 
ATOM   12804 C  CA  . VAL F 1 183 ? 43.042  12.806  47.454  1.00 28.59  ? 183 VAL F CA  1 
ATOM   12805 C  C   . VAL F 1 183 ? 44.446  12.319  47.778  1.00 28.41  ? 183 VAL F C   1 
ATOM   12806 O  O   . VAL F 1 183 ? 45.172  12.926  48.576  1.00 26.35  ? 183 VAL F O   1 
ATOM   12807 C  CB  . VAL F 1 183 ? 43.028  13.753  46.231  1.00 27.70  ? 183 VAL F CB  1 
ATOM   12808 C  CG1 . VAL F 1 183 ? 41.608  14.177  45.886  1.00 27.50  ? 183 VAL F CG1 1 
ATOM   12809 C  CG2 . VAL F 1 183 ? 43.892  14.972  46.466  1.00 27.74  ? 183 VAL F CG2 1 
ATOM   12810 N  N   . GLN F 1 184 ? 44.799  11.207  47.134  1.00 28.36  ? 184 GLN F N   1 
ATOM   12811 C  CA  . GLN F 1 184 ? 46.151  10.692  47.166  1.00 26.82  ? 184 GLN F CA  1 
ATOM   12812 C  C   . GLN F 1 184 ? 46.416  9.994   45.855  1.00 25.11  ? 184 GLN F C   1 
ATOM   12813 O  O   . GLN F 1 184 ? 45.683  9.090   45.520  1.00 28.62  ? 184 GLN F O   1 
ATOM   12814 C  CB  . GLN F 1 184 ? 46.325  9.621   48.242  1.00 26.69  ? 184 GLN F CB  1 
ATOM   12815 C  CG  . GLN F 1 184 ? 46.331  10.139  49.675  1.00 27.13  ? 184 GLN F CG  1 
ATOM   12816 C  CD  . GLN F 1 184 ? 46.770  9.018   50.584  1.00 30.10  ? 184 GLN F CD  1 
ATOM   12817 O  OE1 . GLN F 1 184 ? 46.098  7.984   50.655  1.00 25.61  ? 184 GLN F OE1 1 
ATOM   12818 N  NE2 . GLN F 1 184 ? 47.949  9.170   51.182  1.00 33.22  ? 184 GLN F NE2 1 
ATOM   12819 N  N   . LYS F 1 185 ? 47.462  10.374  45.133  1.00 27.24  ? 185 LYS F N   1 
ATOM   12820 C  CA  . LYS F 1 185 ? 47.837  9.673   43.922  1.00 24.20  ? 185 LYS F CA  1 
ATOM   12821 C  C   . LYS F 1 185 ? 48.771  8.520   44.271  1.00 21.61  ? 185 LYS F C   1 
ATOM   12822 O  O   . LYS F 1 185 ? 49.763  8.746   44.919  1.00 21.92  ? 185 LYS F O   1 
ATOM   12823 C  CB  . LYS F 1 185 ? 48.449  10.692  42.963  1.00 26.06  ? 185 LYS F CB  1 
ATOM   12824 C  CG  . LYS F 1 185 ? 48.974  10.025  41.709  1.00 29.03  ? 185 LYS F CG  1 
ATOM   12825 C  CD  . LYS F 1 185 ? 49.192  10.889  40.487  1.00 28.72  ? 185 LYS F CD  1 
ATOM   12826 C  CE  . LYS F 1 185 ? 50.294  11.811  40.695  1.00 31.24  ? 185 LYS F CE  1 
ATOM   12827 N  NZ  . LYS F 1 185 ? 50.465  12.531  39.433  1.00 32.80  ? 185 LYS F NZ  1 
ATOM   12828 N  N   . TYR F 1 186 ? 48.485  7.304   43.812  1.00 21.54  ? 186 TYR F N   1 
ATOM   12829 C  CA  . TYR F 1 186 ? 49.262  6.124   44.188  1.00 20.50  ? 186 TYR F CA  1 
ATOM   12830 C  C   . TYR F 1 186 ? 49.850  5.527   42.944  1.00 20.83  ? 186 TYR F C   1 
ATOM   12831 O  O   . TYR F 1 186 ? 49.161  5.388   41.965  1.00 24.77  ? 186 TYR F O   1 
ATOM   12832 C  CB  . TYR F 1 186 ? 48.526  4.961   44.862  1.00 21.48  ? 186 TYR F CB  1 
ATOM   12833 C  CG  . TYR F 1 186 ? 48.207  5.181   46.346  1.00 23.88  ? 186 TYR F CG  1 
ATOM   12834 C  CD1 . TYR F 1 186 ? 47.095  5.929   46.739  1.00 25.88  ? 186 TYR F CD1 1 
ATOM   12835 C  CD2 . TYR F 1 186 ? 48.969  4.624   47.365  1.00 23.82  ? 186 TYR F CD2 1 
ATOM   12836 C  CE1 . TYR F 1 186 ? 46.775  6.165   48.066  1.00 26.57  ? 186 TYR F CE1 1 
ATOM   12837 C  CE2 . TYR F 1 186 ? 48.661  4.852   48.698  1.00 25.56  ? 186 TYR F CE2 1 
ATOM   12838 C  CZ  . TYR F 1 186 ? 47.566  5.628   49.059  1.00 26.57  ? 186 TYR F CZ  1 
ATOM   12839 O  OH  . TYR F 1 186 ? 47.221  5.910   50.352  1.00 27.07  ? 186 TYR F OH  1 
ATOM   12840 N  N   . LEU F 1 187 ? 51.116  5.132   42.999  1.00 24.96  ? 187 LEU F N   1 
ATOM   12841 C  CA  . LEU F 1 187 ? 51.722  4.378   41.910  1.00 25.50  ? 187 LEU F CA  1 
ATOM   12842 C  C   . LEU F 1 187 ? 52.021  2.975   42.403  1.00 28.54  ? 187 LEU F C   1 
ATOM   12843 O  O   . LEU F 1 187 ? 52.466  2.790   43.526  1.00 37.51  ? 187 LEU F O   1 
ATOM   12844 C  CB  . LEU F 1 187 ? 53.008  5.089   41.518  1.00 27.79  ? 187 LEU F CB  1 
ATOM   12845 C  CG  . LEU F 1 187 ? 52.826  6.494   40.932  1.00 33.71  ? 187 LEU F CG  1 
ATOM   12846 C  CD1 . LEU F 1 187 ? 54.138  7.165   40.800  1.00 35.48  ? 187 LEU F CD1 1 
ATOM   12847 C  CD2 . LEU F 1 187 ? 52.142  6.423   39.569  1.00 37.66  ? 187 LEU F CD2 1 
ATOM   12848 N  N   . HIS F 1 188 ? 51.796  1.987   41.564  1.00 25.06  ? 188 HIS F N   1 
ATOM   12849 C  CA  . HIS F 1 188 ? 51.895  0.614   42.011  1.00 27.23  ? 188 HIS F CA  1 
ATOM   12850 C  C   . HIS F 1 188 ? 53.170  -0.040  41.492  1.00 26.32  ? 188 HIS F C   1 
ATOM   12851 O  O   . HIS F 1 188 ? 53.684  0.331   40.474  1.00 28.12  ? 188 HIS F O   1 
ATOM   12852 C  CB  . HIS F 1 188 ? 50.682  -0.184  41.530  1.00 25.86  ? 188 HIS F CB  1 
ATOM   12853 C  CG  . HIS F 1 188 ? 49.423  0.236   42.172  1.00 28.92  ? 188 HIS F CG  1 
ATOM   12854 N  ND1 . HIS F 1 188 ? 49.142  0.028   43.503  1.00 32.33  ? 188 HIS F ND1 1 
ATOM   12855 C  CD2 . HIS F 1 188 ? 48.369  0.886   41.682  1.00 31.92  ? 188 HIS F CD2 1 
ATOM   12856 C  CE1 . HIS F 1 188 ? 47.947  0.543   43.788  1.00 33.54  ? 188 HIS F CE1 1 
ATOM   12857 N  NE2 . HIS F 1 188 ? 47.452  1.061   42.695  1.00 34.51  ? 188 HIS F NE2 1 
ATOM   12858 N  N   . ASP F 1 189 ? 53.663  -1.031  42.219  1.00 29.33  ? 189 ASP F N   1 
ATOM   12859 C  CA  . ASP F 1 189 ? 54.706  -1.906  41.751  1.00 29.01  ? 189 ASP F CA  1 
ATOM   12860 C  C   . ASP F 1 189 ? 54.025  -3.169  41.245  1.00 28.76  ? 189 ASP F C   1 
ATOM   12861 O  O   . ASP F 1 189 ? 53.859  -4.158  41.953  1.00 26.53  ? 189 ASP F O   1 
ATOM   12862 C  CB  . ASP F 1 189 ? 55.749  -2.151  42.833  1.00 29.91  ? 189 ASP F CB  1 
ATOM   12863 C  CG  . ASP F 1 189 ? 56.913  -3.040  42.440  1.00 28.89  ? 189 ASP F CG  1 
ATOM   12864 O  OD1 . ASP F 1 189 ? 56.883  -3.657  41.336  1.00 30.75  ? 189 ASP F OD1 1 
ATOM   12865 O  OD2 . ASP F 1 189 ? 57.822  -3.139  43.260  1.00 30.46  ? 189 ASP F OD2 1 
ATOM   12866 N  N   . ILE F 1 190 ? 53.709  -3.113  39.963  1.00 30.54  ? 190 ILE F N   1 
ATOM   12867 C  CA  . ILE F 1 190 ? 53.028  -4.179  39.250  1.00 32.42  ? 190 ILE F CA  1 
ATOM   12868 C  C   . ILE F 1 190 ? 53.902  -5.419  39.178  1.00 29.66  ? 190 ILE F C   1 
ATOM   12869 O  O   . ILE F 1 190 ? 53.372  -6.517  39.267  1.00 29.59  ? 190 ILE F O   1 
ATOM   12870 C  CB  . ILE F 1 190 ? 52.562  -3.666  37.868  1.00 31.84  ? 190 ILE F CB  1 
ATOM   12871 C  CG1 . ILE F 1 190 ? 51.415  -2.697  38.055  1.00 32.65  ? 190 ILE F CG1 1 
ATOM   12872 C  CG2 . ILE F 1 190 ? 52.168  -4.766  36.889  1.00 28.39  ? 190 ILE F CG2 1 
ATOM   12873 C  CD1 . ILE F 1 190 ? 50.189  -3.311  38.698  1.00 32.81  ? 190 ILE F CD1 1 
ATOM   12874 N  N   . ASP F 1 191 ? 55.222  -5.250  39.036  1.00 34.48  ? 191 ASP F N   1 
ATOM   12875 C  CA  . ASP F 1 191 ? 56.100  -6.404  38.884  1.00 37.05  ? 191 ASP F CA  1 
ATOM   12876 C  C   . ASP F 1 191 ? 56.034  -7.244  40.152  1.00 30.64  ? 191 ASP F C   1 
ATOM   12877 O  O   . ASP F 1 191 ? 55.787  -8.444  40.097  1.00 27.64  ? 191 ASP F O   1 
ATOM   12878 C  CB  . ASP F 1 191 ? 57.518  -6.023  38.502  1.00 41.59  ? 191 ASP F CB  1 
ATOM   12879 C  CG  . ASP F 1 191 ? 57.698  -5.601  37.047  1.00 52.11  ? 191 ASP F CG  1 
ATOM   12880 O  OD1 . ASP F 1 191 ? 57.333  -6.385  36.123  1.00 57.04  ? 191 ASP F OD1 1 
ATOM   12881 O  OD2 . ASP F 1 191 ? 58.216  -4.490  36.832  1.00 62.99  ? 191 ASP F OD2 1 
ATOM   12882 N  N   . ALA F 1 192 ? 56.194  -6.572  41.282  1.00 29.42  ? 192 ALA F N   1 
ATOM   12883 C  CA  . ALA F 1 192 ? 56.130  -7.231  42.577  1.00 30.86  ? 192 ALA F CA  1 
ATOM   12884 C  C   . ALA F 1 192 ? 54.793  -7.931  42.761  1.00 31.53  ? 192 ALA F C   1 
ATOM   12885 O  O   . ALA F 1 192 ? 54.737  -9.034  43.293  1.00 29.87  ? 192 ALA F O   1 
ATOM   12886 C  CB  . ALA F 1 192 ? 56.352  -6.226  43.708  1.00 33.43  ? 192 ALA F CB  1 
ATOM   12887 N  N   . TRP F 1 193 ? 53.730  -7.196  42.432  1.00 33.95  ? 193 TRP F N   1 
ATOM   12888 C  CA  . TRP F 1 193 ? 52.378  -7.619  42.721  1.00 33.69  ? 193 TRP F CA  1 
ATOM   12889 C  C   . TRP F 1 193 ? 52.058  -8.862  41.905  1.00 32.15  ? 193 TRP F C   1 
ATOM   12890 O  O   . TRP F 1 193 ? 51.473  -9.794  42.443  1.00 28.79  ? 193 TRP F O   1 
ATOM   12891 C  CB  . TRP F 1 193 ? 51.418  -6.480  42.376  1.00 40.01  ? 193 TRP F CB  1 
ATOM   12892 C  CG  . TRP F 1 193 ? 49.946  -6.811  42.514  1.00 45.73  ? 193 TRP F CG  1 
ATOM   12893 C  CD1 . TRP F 1 193 ? 49.004  -6.950  41.532  1.00 39.62  ? 193 TRP F CD1 1 
ATOM   12894 C  CD2 . TRP F 1 193 ? 49.244  -7.013  43.761  1.00 41.12  ? 193 TRP F CD2 1 
ATOM   12895 N  NE1 . TRP F 1 193 ? 47.776  -7.204  42.078  1.00 33.91  ? 193 TRP F NE1 1 
ATOM   12896 C  CE2 . TRP F 1 193 ? 47.890  -7.254  43.435  1.00 34.34  ? 193 TRP F CE2 1 
ATOM   12897 C  CE3 . TRP F 1 193 ? 49.652  -7.010  45.094  1.00 31.67  ? 193 TRP F CE3 1 
ATOM   12898 C  CZ2 . TRP F 1 193 ? 46.924  -7.491  44.393  1.00 31.51  ? 193 TRP F CZ2 1 
ATOM   12899 C  CZ3 . TRP F 1 193 ? 48.689  -7.233  46.034  1.00 36.15  ? 193 TRP F CZ3 1 
ATOM   12900 C  CH2 . TRP F 1 193 ? 47.344  -7.454  45.691  1.00 35.19  ? 193 TRP F CH2 1 
ATOM   12901 N  N   . GLU F 1 194 ? 52.477  -8.866  40.624  1.00 35.57  ? 194 GLU F N   1 
ATOM   12902 C  CA  . GLU F 1 194 ? 52.236  -9.996  39.735  1.00 39.64  ? 194 GLU F CA  1 
ATOM   12903 C  C   . GLU F 1 194 ? 53.095  -11.195 40.147  1.00 36.31  ? 194 GLU F C   1 
ATOM   12904 O  O   . GLU F 1 194 ? 52.887  -12.317 39.724  1.00 35.47  ? 194 GLU F O   1 
ATOM   12905 C  CB  . GLU F 1 194 ? 52.417  -9.600  38.273  1.00 47.33  ? 194 GLU F CB  1 
ATOM   12906 C  CG  . GLU F 1 194 ? 51.230  -9.973  37.388  1.00 60.75  ? 194 GLU F CG  1 
ATOM   12907 C  CD  . GLU F 1 194 ? 50.076  -8.985  37.485  1.00 74.29  ? 194 GLU F CD  1 
ATOM   12908 O  OE1 . GLU F 1 194 ? 50.292  -7.883  36.922  1.00 74.54  ? 194 GLU F OE1 1 
ATOM   12909 O  OE2 . GLU F 1 194 ? 49.008  -9.287  38.105  1.00 78.36  ? 194 GLU F OE2 1 
ATOM   12910 N  N   . GLY F 1 195 ? 54.051  -10.987 41.037  1.00 36.74  ? 195 GLY F N   1 
ATOM   12911 C  CA  . GLY F 1 195 ? 54.826  -12.101 41.539  1.00 35.93  ? 195 GLY F CA  1 
ATOM   12912 C  C   . GLY F 1 195 ? 54.048  -12.920 42.555  1.00 35.60  ? 195 GLY F C   1 
ATOM   12913 O  O   . GLY F 1 195 ? 54.501  -13.983 42.923  1.00 39.87  ? 195 GLY F O   1 
ATOM   12914 N  N   . LEU F 1 196 ? 52.934  -12.397 43.074  1.00 39.40  ? 196 LEU F N   1 
ATOM   12915 C  CA  . LEU F 1 196 ? 52.148  -13.089 44.099  1.00 37.38  ? 196 LEU F CA  1 
ATOM   12916 C  C   . LEU F 1 196 ? 51.156  -14.021 43.413  1.00 37.55  ? 196 LEU F C   1 
ATOM   12917 O  O   . LEU F 1 196 ? 50.653  -13.716 42.332  1.00 38.51  ? 196 LEU F O   1 
ATOM   12918 C  CB  . LEU F 1 196 ? 51.366  -12.151 45.010  1.00 37.70  ? 196 LEU F CB  1 
ATOM   12919 C  CG  . LEU F 1 196 ? 52.082  -11.635 46.262  1.00 40.52  ? 196 LEU F CG  1 
ATOM   12920 C  CD1 . LEU F 1 196 ? 53.386  -11.013 45.864  1.00 48.44  ? 196 LEU F CD1 1 
ATOM   12921 C  CD2 . LEU F 1 196 ? 51.231  -10.610 47.036  1.00 39.28  ? 196 LEU F CD2 1 
ATOM   12922 N  N   . SER F 1 197 ? 50.883  -15.147 44.067  1.00 38.55  ? 197 SER F N   1 
ATOM   12923 C  CA  . SER F 1 197 ? 49.797  -16.014 43.652  1.00 38.72  ? 197 SER F CA  1 
ATOM   12924 C  C   . SER F 1 197 ? 48.513  -15.228 43.865  1.00 36.33  ? 197 SER F C   1 
ATOM   12925 O  O   . SER F 1 197 ? 48.490  -14.243 44.616  1.00 35.03  ? 197 SER F O   1 
ATOM   12926 C  CB  . SER F 1 197 ? 49.754  -17.304 44.452  1.00 34.71  ? 197 SER F CB  1 
ATOM   12927 O  OG  . SER F 1 197 ? 49.404  -16.970 45.786  1.00 30.84  ? 197 SER F OG  1 
ATOM   12928 N  N   . VAL F 1 198 ? 47.442  -15.691 43.226  1.00 39.13  ? 198 VAL F N   1 
ATOM   12929 C  CA  . VAL F 1 198 ? 46.157  -15.057 43.452  1.00 39.34  ? 198 VAL F CA  1 
ATOM   12930 C  C   . VAL F 1 198 ? 45.775  -15.176 44.937  1.00 42.97  ? 198 VAL F C   1 
ATOM   12931 O  O   . VAL F 1 198 ? 45.288  -14.182 45.506  1.00 37.24  ? 198 VAL F O   1 
ATOM   12932 C  CB  . VAL F 1 198 ? 45.080  -15.630 42.524  1.00 33.76  ? 198 VAL F CB  1 
ATOM   12933 C  CG1 . VAL F 1 198 ? 43.711  -15.116 42.943  1.00 34.08  ? 198 VAL F CG1 1 
ATOM   12934 C  CG2 . VAL F 1 198 ? 45.410  -15.311 41.072  1.00 29.77  ? 198 VAL F CG2 1 
ATOM   12935 N  N   . GLU F 1 199 ? 46.010  -16.364 45.562  1.00 35.21  ? 199 GLU F N   1 
ATOM   12936 C  CA  . GLU F 1 199 ? 45.596  -16.549 46.938  1.00 36.98  ? 199 GLU F CA  1 
ATOM   12937 C  C   . GLU F 1 199 ? 46.316  -15.509 47.813  1.00 34.77  ? 199 GLU F C   1 
ATOM   12938 O  O   . GLU F 1 199 ? 45.704  -14.900 48.698  1.00 32.29  ? 199 GLU F O   1 
ATOM   12939 C  CB  . GLU F 1 199 ? 45.706  -18.016 47.357  1.00 47.90  ? 199 GLU F CB  1 
ATOM   12940 C  CG  . GLU F 1 199 ? 44.956  -18.331 48.660  1.00 62.41  ? 199 GLU F CG  1 
ATOM   12941 C  CD  . GLU F 1 199 ? 45.114  -19.745 49.233  1.00 70.05  ? 199 GLU F CD  1 
ATOM   12942 O  OE1 . GLU F 1 199 ? 46.284  -20.182 49.323  1.00 71.63  ? 199 GLU F OE1 1 
ATOM   12943 O  OE2 . GLU F 1 199 ? 44.116  -20.428 49.588  1.00 66.03  ? 199 GLU F OE2 1 
ATOM   12944 N  N   . ALA F 1 200 ? 47.599  -15.222 47.530  1.00 28.40  ? 200 ALA F N   1 
ATOM   12945 C  CA  . ALA F 1 200 ? 48.340  -14.258 48.328  1.00 25.70  ? 200 ALA F CA  1 
ATOM   12946 C  C   . ALA F 1 200 ? 47.817  -12.824 48.157  1.00 29.84  ? 200 ALA F C   1 
ATOM   12947 O  O   . ALA F 1 200 ? 47.810  -11.996 49.100  1.00 26.87  ? 200 ALA F O   1 
ATOM   12948 C  CB  . ALA F 1 200 ? 49.745  -14.338 47.893  1.00 25.91  ? 200 ALA F CB  1 
ATOM   12949 N  N   . GLN F 1 201 ? 47.408  -12.514 46.915  1.00 26.44  ? 201 GLN F N   1 
ATOM   12950 C  CA  . GLN F 1 201 ? 46.860  -11.199 46.641  1.00 27.63  ? 201 GLN F CA  1 
ATOM   12951 C  C   . GLN F 1 201 ? 45.546  -11.000 47.393  1.00 24.77  ? 201 GLN F C   1 
ATOM   12952 O  O   . GLN F 1 201 ? 45.258  -9.924  47.906  1.00 20.43  ? 201 GLN F O   1 
ATOM   12953 C  CB  . GLN F 1 201 ? 46.619  -11.085 45.143  1.00 30.04  ? 201 GLN F CB  1 
ATOM   12954 C  CG  . GLN F 1 201 ? 47.883  -10.904 44.324  1.00 30.89  ? 201 GLN F CG  1 
ATOM   12955 C  CD  . GLN F 1 201 ? 47.584  -10.726 42.854  1.00 28.35  ? 201 GLN F CD  1 
ATOM   12956 O  OE1 . GLN F 1 201 ? 46.440  -10.876 42.424  1.00 28.45  ? 201 GLN F OE1 1 
ATOM   12957 N  NE2 . GLN F 1 201 ? 48.602  -10.439 42.059  1.00 27.56  ? 201 GLN F NE2 1 
ATOM   12958 N  N   . GLU F 1 202 ? 44.736  -12.063 47.427  1.00 27.99  ? 202 GLU F N   1 
ATOM   12959 C  CA  . GLU F 1 202 ? 43.448  -12.039 48.113  1.00 30.35  ? 202 GLU F CA  1 
ATOM   12960 C  C   . GLU F 1 202 ? 43.632  -11.800 49.608  1.00 30.66  ? 202 GLU F C   1 
ATOM   12961 O  O   . GLU F 1 202 ? 42.792  -11.161 50.241  1.00 29.72  ? 202 GLU F O   1 
ATOM   12962 C  CB  . GLU F 1 202 ? 42.693  -13.358 47.920  1.00 32.59  ? 202 GLU F CB  1 
ATOM   12963 C  CG  . GLU F 1 202 ? 42.147  -13.511 46.504  1.00 31.36  ? 202 GLU F CG  1 
ATOM   12964 C  CD  . GLU F 1 202 ? 41.590  -14.865 46.130  1.00 33.97  ? 202 GLU F CD  1 
ATOM   12965 O  OE1 . GLU F 1 202 ? 41.929  -15.855 46.825  1.00 32.93  ? 202 GLU F OE1 1 
ATOM   12966 O  OE2 . GLU F 1 202 ? 40.805  -14.914 45.139  1.00 33.47  ? 202 GLU F OE2 1 
ATOM   12967 N  N   . ARG F 1 203 ? 44.734  -12.342 50.143  1.00 31.43  ? 203 ARG F N   1 
ATOM   12968 C  CA  . ARG F 1 203 ? 45.089  -12.112 51.525  1.00 34.74  ? 203 ARG F CA  1 
ATOM   12969 C  C   . ARG F 1 203 ? 45.458  -10.643 51.751  1.00 32.93  ? 203 ARG F C   1 
ATOM   12970 O  O   . ARG F 1 203 ? 45.179  -10.081 52.823  1.00 36.01  ? 203 ARG F O   1 
ATOM   12971 C  CB  . ARG F 1 203 ? 46.201  -13.077 51.950  1.00 36.99  ? 203 ARG F CB  1 
ATOM   12972 C  CG  . ARG F 1 203 ? 45.696  -14.417 52.445  1.00 39.67  ? 203 ARG F CG  1 
ATOM   12973 C  CD  . ARG F 1 203 ? 46.841  -15.431 52.541  1.00 51.12  ? 203 ARG F CD  1 
ATOM   12974 N  NE  . ARG F 1 203 ? 46.292  -16.735 52.158  1.00 66.13  ? 203 ARG F NE  1 
ATOM   12975 C  CZ  . ARG F 1 203 ? 45.481  -17.480 52.929  1.00 79.91  ? 203 ARG F CZ  1 
ATOM   12976 N  NH1 . ARG F 1 203 ? 45.649  -17.531 54.246  1.00 72.54  ? 203 ARG F NH1 1 
ATOM   12977 N  NH2 . ARG F 1 203 ? 44.560  -18.244 52.352  1.00 82.05  ? 203 ARG F NH2 1 
ATOM   12978 N  N   . VAL F 1 204 ? 46.110  -10.014 50.767  1.00 29.12  ? 204 VAL F N   1 
ATOM   12979 C  CA  . VAL F 1 204 ? 46.461  -8.607  50.929  1.00 30.32  ? 204 VAL F CA  1 
ATOM   12980 C  C   . VAL F 1 204 ? 45.205  -7.722  50.976  1.00 32.25  ? 204 VAL F C   1 
ATOM   12981 O  O   . VAL F 1 204 ? 45.150  -6.781  51.777  1.00 34.27  ? 204 VAL F O   1 
ATOM   12982 C  CB  . VAL F 1 204 ? 47.423  -8.182  49.814  1.00 29.38  ? 204 VAL F CB  1 
ATOM   12983 C  CG1 . VAL F 1 204 ? 47.673  -6.688  49.814  1.00 28.92  ? 204 VAL F CG1 1 
ATOM   12984 C  CG2 . VAL F 1 204 ? 48.715  -8.967  49.908  1.00 34.11  ? 204 VAL F CG2 1 
ATOM   12985 N  N   . ILE F 1 205 ? 44.202  -8.018  50.124  1.00 31.71  ? 205 ILE F N   1 
ATOM   12986 C  CA  . ILE F 1 205 ? 43.038  -7.149  49.953  1.00 30.98  ? 205 ILE F CA  1 
ATOM   12987 C  C   . ILE F 1 205 ? 41.973  -7.532  50.990  1.00 29.31  ? 205 ILE F C   1 
ATOM   12988 O  O   . ILE F 1 205 ? 41.417  -6.667  51.670  1.00 25.27  ? 205 ILE F O   1 
ATOM   12989 C  CB  . ILE F 1 205 ? 42.483  -7.204  48.506  1.00 30.31  ? 205 ILE F CB  1 
ATOM   12990 C  CG1 . ILE F 1 205 ? 43.517  -6.794  47.442  1.00 34.03  ? 205 ILE F CG1 1 
ATOM   12991 C  CG2 . ILE F 1 205 ? 41.215  -6.364  48.351  1.00 31.90  ? 205 ILE F CG2 1 
ATOM   12992 C  CD1 . ILE F 1 205 ? 43.935  -5.329  47.506  1.00 33.10  ? 205 ILE F CD1 1 
ATOM   12993 N  N   . GLY F 1 206 ? 41.671  -8.834  51.093  1.00 26.55  ? 206 GLY F N   1 
ATOM   12994 C  CA  . GLY F 1 206 ? 40.667  -9.286  52.038  1.00 27.17  ? 206 GLY F CA  1 
ATOM   12995 C  C   . GLY F 1 206 ? 39.381  -9.704  51.336  1.00 28.88  ? 206 GLY F C   1 
ATOM   12996 O  O   . GLY F 1 206 ? 38.366  -9.871  51.987  1.00 34.23  ? 206 GLY F O   1 
ATOM   12997 N  N   . ARG F 1 207 ? 39.427  -9.891  50.013  1.00 28.54  ? 207 ARG F N   1 
ATOM   12998 C  CA  . ARG F 1 207 ? 38.279  -10.352 49.242  1.00 25.61  ? 207 ARG F CA  1 
ATOM   12999 C  C   . ARG F 1 207 ? 38.785  -11.228 48.119  1.00 26.68  ? 207 ARG F C   1 
ATOM   13000 O  O   . ARG F 1 207 ? 39.982  -11.174 47.801  1.00 31.22  ? 207 ARG F O   1 
ATOM   13001 C  CB  . ARG F 1 207 ? 37.519  -9.243  48.527  1.00 23.53  ? 207 ARG F CB  1 
ATOM   13002 C  CG  . ARG F 1 207 ? 37.307  -8.032  49.406  1.00 26.48  ? 207 ARG F CG  1 
ATOM   13003 C  CD  . ARG F 1 207 ? 36.616  -6.945  48.638  1.00 31.40  ? 207 ARG F CD  1 
ATOM   13004 N  NE  . ARG F 1 207 ? 35.253  -7.367  48.299  1.00 30.16  ? 207 ARG F NE  1 
ATOM   13005 C  CZ  . ARG F 1 207 ? 34.206  -7.256  49.081  1.00 30.56  ? 207 ARG F CZ  1 
ATOM   13006 N  NH1 . ARG F 1 207 ? 33.197  -8.036  48.793  1.00 29.84  ? 207 ARG F NH1 1 
ATOM   13007 N  NH2 . ARG F 1 207 ? 34.187  -6.446  50.142  1.00 35.01  ? 207 ARG F NH2 1 
ATOM   13008 N  N   . ARG F 1 208 ? 37.879  -12.007 47.511  1.00 29.80  ? 208 ARG F N   1 
ATOM   13009 C  CA  . ARG F 1 208 ? 38.260  -12.929 46.435  1.00 35.27  ? 208 ARG F CA  1 
ATOM   13010 C  C   . ARG F 1 208 ? 38.455  -12.125 45.153  1.00 33.62  ? 208 ARG F C   1 
ATOM   13011 O  O   . ARG F 1 208 ? 37.740  -11.153 44.929  1.00 37.81  ? 208 ARG F O   1 
ATOM   13012 C  CB  . ARG F 1 208 ? 37.245  -14.046 46.162  1.00 38.47  ? 208 ARG F CB  1 
ATOM   13013 C  CG  . ARG F 1 208 ? 36.970  -14.964 47.342  1.00 47.30  ? 208 ARG F CG  1 
ATOM   13014 C  CD  . ARG F 1 208 ? 38.170  -15.720 47.928  1.00 58.33  ? 208 ARG F CD  1 
ATOM   13015 N  NE  . ARG F 1 208 ? 38.765  -16.648 46.950  1.00 79.03  ? 208 ARG F NE  1 
ATOM   13016 C  CZ  . ARG F 1 208 ? 38.179  -17.706 46.342  1.00 69.75  ? 208 ARG F CZ  1 
ATOM   13017 N  NH1 . ARG F 1 208 ? 36.994  -18.123 46.725  1.00 75.04  ? 208 ARG F NH1 1 
ATOM   13018 N  NH2 . ARG F 1 208 ? 38.783  -18.377 45.373  1.00 56.47  ? 208 ARG F NH2 1 
ATOM   13019 N  N   . LYS F 1 209 ? 39.405  -12.540 44.306  1.00 34.06  ? 209 LYS F N   1 
ATOM   13020 C  CA  . LYS F 1 209 ? 39.742  -11.767 43.114  1.00 33.62  ? 209 LYS F CA  1 
ATOM   13021 C  C   . LYS F 1 209 ? 38.647  -11.849 42.042  1.00 30.22  ? 209 LYS F C   1 
ATOM   13022 O  O   . LYS F 1 209 ? 38.142  -10.797 41.634  1.00 26.37  ? 209 LYS F O   1 
ATOM   13023 C  CB  . LYS F 1 209 ? 41.099  -12.162 42.525  1.00 30.75  ? 209 LYS F CB  1 
ATOM   13024 C  CG  . LYS F 1 209 ? 41.601  -11.159 41.510  1.00 31.23  ? 209 LYS F CG  1 
ATOM   13025 C  CD  . LYS F 1 209 ? 43.101  -11.284 41.246  1.00 29.75  ? 209 LYS F CD  1 
ATOM   13026 C  CE  . LYS F 1 209 ? 43.574  -10.049 40.523  1.00 30.95  ? 209 LYS F CE  1 
ATOM   13027 N  NZ  . LYS F 1 209 ? 44.917  -10.289 40.036  1.00 32.88  ? 209 LYS F NZ  1 
ATOM   13028 N  N   . MET F 1 210 ? 38.304  -13.079 41.593  1.00 30.34  ? 210 MET F N   1 
ATOM   13029 C  CA  . MET F 1 210 ? 37.393  -13.246 40.451  1.00 32.17  ? 210 MET F CA  1 
ATOM   13030 C  C   . MET F 1 210 ? 35.975  -12.895 40.895  1.00 30.57  ? 210 MET F C   1 
ATOM   13031 O  O   . MET F 1 210 ? 35.363  -12.044 40.273  1.00 30.64  ? 210 MET F O   1 
ATOM   13032 C  CB  . MET F 1 210 ? 37.441  -14.591 39.681  1.00 34.93  ? 210 MET F CB  1 
ATOM   13033 C  CG  . MET F 1 210 ? 38.812  -15.005 39.041  1.00 38.09  ? 210 MET F CG  1 
ATOM   13034 S  SD  . MET F 1 210 ? 39.968  -13.852 38.206  1.00 53.93  ? 210 MET F SD  1 
ATOM   13035 C  CE  . MET F 1 210 ? 38.799  -13.150 37.025  1.00 66.95  ? 210 MET F CE  1 
ATOM   13036 N  N   . THR F 1 211 ? 35.500  -13.434 42.025  1.00 31.74  ? 211 THR F N   1 
ATOM   13037 C  CA  . THR F 1 211 ? 34.099  -13.302 42.441  1.00 30.20  ? 211 THR F CA  1 
ATOM   13038 C  C   . THR F 1 211 ? 33.819  -12.099 43.357  1.00 28.18  ? 211 THR F C   1 
ATOM   13039 O  O   . THR F 1 211 ? 32.663  -11.766 43.561  1.00 32.01  ? 211 THR F O   1 
ATOM   13040 C  CB  . THR F 1 211 ? 33.663  -14.607 43.112  1.00 30.75  ? 211 THR F CB  1 
ATOM   13041 O  OG1 . THR F 1 211 ? 34.439  -14.785 44.302  1.00 33.36  ? 211 THR F OG1 1 
ATOM   13042 C  CG2 . THR F 1 211 ? 33.899  -15.788 42.193  1.00 31.54  ? 211 THR F CG2 1 
ATOM   13043 N  N   . ASP F 1 212 ? 34.834  -11.474 43.964  1.00 27.98  ? 212 ASP F N   1 
ATOM   13044 C  CA  . ASP F 1 212 ? 34.679  -10.259 44.777  1.00 29.02  ? 212 ASP F CA  1 
ATOM   13045 C  C   . ASP F 1 212 ? 33.941  -10.538 46.079  1.00 29.64  ? 212 ASP F C   1 
ATOM   13046 O  O   . ASP F 1 212 ? 33.508  -9.611  46.740  1.00 30.36  ? 212 ASP F O   1 
ATOM   13047 C  CB  . ASP F 1 212 ? 34.012  -9.104  44.056  1.00 28.86  ? 212 ASP F CB  1 
ATOM   13048 C  CG  . ASP F 1 212 ? 34.169  -7.712  44.655  1.00 30.49  ? 212 ASP F CG  1 
ATOM   13049 O  OD1 . ASP F 1 212 ? 35.170  -7.428  45.403  1.00 33.46  ? 212 ASP F OD1 1 
ATOM   13050 O  OD2 . ASP F 1 212 ? 33.277  -6.910  44.311  1.00 30.86  ? 212 ASP F OD2 1 
ATOM   13051 N  N   . VAL F 1 213 ? 33.890  -11.803 46.499  1.00 32.56  ? 213 VAL F N   1 
ATOM   13052 C  CA  . VAL F 1 213 ? 33.241  -12.176 47.750  1.00 33.03  ? 213 VAL F CA  1 
ATOM   13053 C  C   . VAL F 1 213 ? 34.220  -11.937 48.899  1.00 29.00  ? 213 VAL F C   1 
ATOM   13054 O  O   . VAL F 1 213 ? 35.401  -12.270 48.775  1.00 28.19  ? 213 VAL F O   1 
ATOM   13055 C  CB  . VAL F 1 213 ? 32.774  -13.650 47.652  1.00 34.16  ? 213 VAL F CB  1 
ATOM   13056 C  CG1 . VAL F 1 213 ? 32.296  -14.182 48.989  1.00 34.28  ? 213 VAL F CG1 1 
ATOM   13057 C  CG2 . VAL F 1 213 ? 31.699  -13.860 46.585  1.00 32.41  ? 213 VAL F CG2 1 
ATOM   13058 N  N   . GLU F 1 214 ? 33.746  -11.353 50.008  1.00 28.05  ? 214 GLU F N   1 
ATOM   13059 C  CA  . GLU F 1 214 ? 34.607  -11.108 51.152  1.00 31.98  ? 214 GLU F CA  1 
ATOM   13060 C  C   . GLU F 1 214 ? 35.097  -12.414 51.787  1.00 35.83  ? 214 GLU F C   1 
ATOM   13061 O  O   . GLU F 1 214 ? 34.365  -13.397 51.847  1.00 31.28  ? 214 GLU F O   1 
ATOM   13062 C  CB  . GLU F 1 214 ? 33.782  -10.290 52.119  1.00 34.17  ? 214 GLU F CB  1 
ATOM   13063 C  CG  . GLU F 1 214 ? 34.622  -9.665  53.220  1.00 37.27  ? 214 GLU F CG  1 
ATOM   13064 C  CD  . GLU F 1 214 ? 33.796  -8.801  54.148  1.00 40.39  ? 214 GLU F CD  1 
ATOM   13065 O  OE1 . GLU F 1 214 ? 32.661  -8.424  53.788  1.00 47.40  ? 214 GLU F OE1 1 
ATOM   13066 O  OE2 . GLU F 1 214 ? 34.302  -8.537  55.251  1.00 45.18  ? 214 GLU F OE2 1 
ATOM   13067 N  N   . LEU F 1 215 ? 36.379  -12.434 52.199  1.00 45.07  ? 215 LEU F N   1 
ATOM   13068 C  CA  . LEU F 1 215 ? 36.959  -13.566 52.909  1.00 46.04  ? 215 LEU F CA  1 
ATOM   13069 C  C   . LEU F 1 215 ? 36.319  -13.620 54.288  1.00 51.19  ? 215 LEU F C   1 
ATOM   13070 O  O   . LEU F 1 215 ? 36.084  -12.574 54.918  1.00 47.13  ? 215 LEU F O   1 
ATOM   13071 C  CB  . LEU F 1 215 ? 38.469  -13.414 53.081  1.00 41.56  ? 215 LEU F CB  1 
ATOM   13072 C  CG  . LEU F 1 215 ? 39.343  -13.466 51.839  1.00 36.58  ? 215 LEU F CG  1 
ATOM   13073 C  CD1 . LEU F 1 215 ? 40.800  -13.343 52.273  1.00 37.28  ? 215 LEU F CD1 1 
ATOM   13074 C  CD2 . LEU F 1 215 ? 39.075  -14.750 51.093  1.00 38.14  ? 215 LEU F CD2 1 
ATOM   13075 N  N   . SER F 1 216 ? 36.100  -14.843 54.777  1.00 58.17  ? 216 SER F N   1 
ATOM   13076 C  CA  . SER F 1 216 ? 35.396  -15.007 56.044  1.00 58.74  ? 216 SER F CA  1 
ATOM   13077 C  C   . SER F 1 216 ? 36.299  -14.539 57.171  1.00 58.63  ? 216 SER F C   1 
ATOM   13078 O  O   . SER F 1 216 ? 37.517  -14.480 56.982  1.00 67.03  ? 216 SER F O   1 
ATOM   13079 C  CB  . SER F 1 216 ? 34.946  -16.417 56.251  1.00 58.29  ? 216 SER F CB  1 
ATOM   13080 O  OG  . SER F 1 216 ? 36.070  -17.280 56.254  1.00 66.90  ? 216 SER F OG  1 
ATOM   13081 N  N   . ASP F 1 217 ? 35.698  -14.206 58.320  1.00 63.43  ? 217 ASP F N   1 
ATOM   13082 C  CA  . ASP F 1 217 ? 36.445  -13.570 59.400  1.00 63.54  ? 217 ASP F CA  1 
ATOM   13083 C  C   . ASP F 1 217 ? 37.561  -14.488 59.893  1.00 57.71  ? 217 ASP F C   1 
ATOM   13084 O  O   . ASP F 1 217 ? 38.642  -14.011 60.230  1.00 54.58  ? 217 ASP F O   1 
ATOM   13085 C  CB  . ASP F 1 217 ? 35.531  -13.078 60.505  1.00 59.63  ? 217 ASP F CB  1 
ATOM   13086 C  CG  . ASP F 1 217 ? 34.478  -12.126 59.979  1.00 64.74  ? 217 ASP F CG  1 
ATOM   13087 O  OD1 . ASP F 1 217 ? 34.822  -11.306 59.101  1.00 71.61  ? 217 ASP F OD1 1 
ATOM   13088 O  OD2 . ASP F 1 217 ? 33.335  -12.240 60.427  1.00 64.78  ? 217 ASP F OD2 1 
ATOM   13089 N  N   . ASP F 1 218 ? 37.340  -15.806 59.883  1.00 59.25  ? 218 ASP F N   1 
ATOM   13090 C  CA  . ASP F 1 218 ? 38.378  -16.690 60.403  1.00 68.17  ? 218 ASP F CA  1 
ATOM   13091 C  C   . ASP F 1 218 ? 39.508  -16.898 59.380  1.00 57.41  ? 218 ASP F C   1 
ATOM   13092 O  O   . ASP F 1 218 ? 40.531  -17.477 59.719  1.00 48.39  ? 218 ASP F O   1 
ATOM   13093 C  CB  . ASP F 1 218 ? 37.769  -17.921 61.060  1.00 76.85  ? 218 ASP F CB  1 
ATOM   13094 C  CG  . ASP F 1 218 ? 36.979  -18.799 60.114  1.00 79.63  ? 218 ASP F CG  1 
ATOM   13095 O  OD1 . ASP F 1 218 ? 37.241  -18.733 58.895  1.00 74.62  ? 218 ASP F OD1 1 
ATOM   13096 O  OD2 . ASP F 1 218 ? 36.100  -19.497 60.613  1.00 87.01  ? 218 ASP F OD2 1 
ATOM   13097 N  N   . VAL F 1 219 ? 39.406  -16.369 58.150  1.00 54.60  ? 219 VAL F N   1 
ATOM   13098 C  CA  . VAL F 1 219 ? 40.541  -16.438 57.226  1.00 46.66  ? 219 VAL F CA  1 
ATOM   13099 C  C   . VAL F 1 219 ? 41.100  -15.058 56.844  1.00 39.49  ? 219 VAL F C   1 
ATOM   13100 O  O   . VAL F 1 219 ? 42.249  -14.968 56.447  1.00 33.14  ? 219 VAL F O   1 
ATOM   13101 C  CB  . VAL F 1 219 ? 40.112  -17.312 56.033  1.00 44.42  ? 219 VAL F CB  1 
ATOM   13102 C  CG1 . VAL F 1 219 ? 40.628  -16.801 54.700  1.00 46.65  ? 219 VAL F CG1 1 
ATOM   13103 C  CG2 . VAL F 1 219 ? 40.498  -18.777 56.240  1.00 41.42  ? 219 VAL F CG2 1 
ATOM   13104 N  N   . LYS F 1 220 ? 40.352  -13.973 57.067  1.00 43.61  ? 220 LYS F N   1 
ATOM   13105 C  CA  . LYS F 1 220 ? 40.788  -12.645 56.655  1.00 44.78  ? 220 LYS F CA  1 
ATOM   13106 C  C   . LYS F 1 220 ? 41.902  -12.110 57.554  1.00 39.84  ? 220 LYS F C   1 
ATOM   13107 O  O   . LYS F 1 220 ? 41.666  -11.802 58.712  1.00 39.92  ? 220 LYS F O   1 
ATOM   13108 C  CB  . LYS F 1 220 ? 39.622  -11.655 56.731  1.00 44.12  ? 220 LYS F CB  1 
ATOM   13109 C  CG  . LYS F 1 220 ? 39.870  -10.273 56.114  1.00 46.38  ? 220 LYS F CG  1 
ATOM   13110 C  CD  . LYS F 1 220 ? 38.803  -9.267  56.521  1.00 48.35  ? 220 LYS F CD  1 
ATOM   13111 C  CE  . LYS F 1 220 ? 37.501  -9.972  56.622  1.00 52.87  ? 220 LYS F CE  1 
ATOM   13112 N  NZ  . LYS F 1 220 ? 36.414  -9.076  56.267  1.00 54.92  ? 220 LYS F NZ  1 
ATOM   13113 N  N   . PRO F 1 221 ? 43.125  -11.890 57.033  1.00 37.12  ? 221 PRO F N   1 
ATOM   13114 C  CA  . PRO F 1 221 ? 44.207  -11.321 57.823  1.00 33.62  ? 221 PRO F CA  1 
ATOM   13115 C  C   . PRO F 1 221 ? 43.834  -9.973  58.421  1.00 30.76  ? 221 PRO F C   1 
ATOM   13116 O  O   . PRO F 1 221 ? 43.043  -9.234  57.861  1.00 29.41  ? 221 PRO F O   1 
ATOM   13117 C  CB  . PRO F 1 221 ? 45.380  -11.169 56.840  1.00 33.36  ? 221 PRO F CB  1 
ATOM   13118 C  CG  . PRO F 1 221 ? 45.056  -12.064 55.689  1.00 34.62  ? 221 PRO F CG  1 
ATOM   13119 C  CD  . PRO F 1 221 ? 43.536  -12.163 55.651  1.00 36.20  ? 221 PRO F CD  1 
ATOM   13120 N  N   . ALA F 1 222 ? 44.496  -9.673  59.535  1.00 29.45  ? 222 ALA F N   1 
ATOM   13121 C  CA  . ALA F 1 222 ? 44.366  -8.418  60.252  1.00 30.57  ? 222 ALA F CA  1 
ATOM   13122 C  C   . ALA F 1 222 ? 45.081  -7.275  59.544  1.00 34.45  ? 222 ALA F C   1 
ATOM   13123 O  O   . ALA F 1 222 ? 44.756  -6.110  59.828  1.00 39.00  ? 222 ALA F O   1 
ATOM   13124 C  CB  . ALA F 1 222 ? 44.976  -8.562  61.623  1.00 28.93  ? 222 ALA F CB  1 
ATOM   13125 N  N   . ASP F 1 223 ? 46.070  -7.607  58.686  1.00 33.63  ? 223 ASP F N   1 
ATOM   13126 C  CA  . ASP F 1 223 ? 46.793  -6.568  57.972  1.00 33.22  ? 223 ASP F CA  1 
ATOM   13127 C  C   . ASP F 1 223 ? 46.273  -6.463  56.541  1.00 34.79  ? 223 ASP F C   1 
ATOM   13128 O  O   . ASP F 1 223 ? 46.866  -5.710  55.753  1.00 35.58  ? 223 ASP F O   1 
ATOM   13129 C  CB  . ASP F 1 223 ? 48.299  -6.724  58.094  1.00 32.94  ? 223 ASP F CB  1 
ATOM   13130 C  CG  . ASP F 1 223 ? 48.826  -8.038  57.538  1.00 32.81  ? 223 ASP F CG  1 
ATOM   13131 O  OD1 . ASP F 1 223 ? 48.015  -8.932  57.301  1.00 33.82  ? 223 ASP F OD1 1 
ATOM   13132 O  OD2 . ASP F 1 223 ? 50.027  -8.132  57.294  1.00 36.62  ? 223 ASP F OD2 1 
ATOM   13133 N  N   . SER F 1 224 ? 45.148  -7.168  56.245  1.00 32.90  ? 224 SER F N   1 
ATOM   13134 C  CA  . SER F 1 224 ? 44.444  -6.995  54.981  1.00 31.42  ? 224 SER F CA  1 
ATOM   13135 C  C   . SER F 1 224 ? 43.811  -5.601  54.912  1.00 31.88  ? 224 SER F C   1 
ATOM   13136 O  O   . SER F 1 224 ? 43.449  -5.009  55.941  1.00 30.06  ? 224 SER F O   1 
ATOM   13137 C  CB  . SER F 1 224 ? 43.432  -8.085  54.717  1.00 30.28  ? 224 SER F CB  1 
ATOM   13138 O  OG  . SER F 1 224 ? 42.269  -7.929  55.498  1.00 27.03  ? 224 SER F OG  1 
ATOM   13139 N  N   . HIS F 1 225 ? 43.699  -5.084  53.675  1.00 27.88  ? 225 HIS F N   1 
ATOM   13140 C  CA  . HIS F 1 225 ? 43.239  -3.723  53.415  1.00 27.86  ? 225 HIS F CA  1 
ATOM   13141 C  C   . HIS F 1 225 ? 41.821  -3.540  53.948  1.00 27.94  ? 225 HIS F C   1 
ATOM   13142 O  O   . HIS F 1 225 ? 41.517  -2.541  54.601  1.00 26.76  ? 225 HIS F O   1 
ATOM   13143 C  CB  . HIS F 1 225 ? 43.367  -3.442  51.913  1.00 27.23  ? 225 HIS F CB  1 
ATOM   13144 C  CG  . HIS F 1 225 ? 42.842  -2.123  51.489  1.00 25.67  ? 225 HIS F CG  1 
ATOM   13145 N  ND1 . HIS F 1 225 ? 43.345  -0.958  52.006  1.00 25.11  ? 225 HIS F ND1 1 
ATOM   13146 C  CD2 . HIS F 1 225 ? 41.842  -1.775  50.652  1.00 25.54  ? 225 HIS F CD2 1 
ATOM   13147 C  CE1 . HIS F 1 225 ? 42.668  0.066   51.495  1.00 26.25  ? 225 HIS F CE1 1 
ATOM   13148 N  NE2 . HIS F 1 225 ? 41.753  -0.406  50.652  1.00 25.49  ? 225 HIS F NE2 1 
ATOM   13149 N  N   . VAL F 1 226 ? 40.969  -4.532  53.659  1.00 27.15  ? 226 VAL F N   1 
ATOM   13150 C  CA  . VAL F 1 226 ? 39.574  -4.490  54.061  1.00 31.01  ? 226 VAL F CA  1 
ATOM   13151 C  C   . VAL F 1 226 ? 39.472  -4.522  55.585  1.00 32.59  ? 226 VAL F C   1 
ATOM   13152 O  O   . VAL F 1 226 ? 38.600  -3.885  56.137  1.00 36.15  ? 226 VAL F O   1 
ATOM   13153 C  CB  . VAL F 1 226 ? 38.802  -5.649  53.408  1.00 31.29  ? 226 VAL F CB  1 
ATOM   13154 C  CG1 . VAL F 1 226 ? 37.585  -6.064  54.194  1.00 34.31  ? 226 VAL F CG1 1 
ATOM   13155 C  CG2 . VAL F 1 226 ? 38.386  -5.267  52.003  1.00 35.54  ? 226 VAL F CG2 1 
ATOM   13156 N  N   . ALA F 1 227 ? 40.356  -5.279  56.250  1.00 34.44  ? 227 ALA F N   1 
ATOM   13157 C  CA  . ALA F 1 227 ? 40.408  -5.334  57.698  1.00 30.15  ? 227 ALA F CA  1 
ATOM   13158 C  C   . ALA F 1 227 ? 40.716  -3.957  58.279  1.00 31.49  ? 227 ALA F C   1 
ATOM   13159 O  O   . ALA F 1 227 ? 39.980  -3.501  59.142  1.00 33.21  ? 227 ALA F O   1 
ATOM   13160 C  CB  . ALA F 1 227 ? 41.430  -6.356  58.153  1.00 30.79  ? 227 ALA F CB  1 
ATOM   13161 N  N   . LEU F 1 228 ? 41.785  -3.288  57.829  1.00 31.05  ? 228 LEU F N   1 
ATOM   13162 C  CA  . LEU F 1 228 ? 42.197  -2.020  58.426  1.00 32.67  ? 228 LEU F CA  1 
ATOM   13163 C  C   . LEU F 1 228 ? 41.266  -0.859  58.087  1.00 33.03  ? 228 LEU F C   1 
ATOM   13164 O  O   . LEU F 1 228 ? 41.252  0.137   58.798  1.00 33.77  ? 228 LEU F O   1 
ATOM   13165 C  CB  . LEU F 1 228 ? 43.631  -1.687  58.032  1.00 36.22  ? 228 LEU F CB  1 
ATOM   13166 C  CG  . LEU F 1 228 ? 44.700  -2.615  58.625  1.00 42.39  ? 228 LEU F CG  1 
ATOM   13167 C  CD1 . LEU F 1 228 ? 46.017  -2.567  57.869  1.00 45.15  ? 228 LEU F CD1 1 
ATOM   13168 C  CD2 . LEU F 1 228 ? 44.946  -2.247  60.066  1.00 40.48  ? 228 LEU F CD2 1 
ATOM   13169 N  N   . THR F 1 229 ? 40.535  -0.920  56.982  1.00 34.14  ? 229 THR F N   1 
ATOM   13170 C  CA  . THR F 1 229 ? 39.728  0.222   56.601  1.00 33.59  ? 229 THR F CA  1 
ATOM   13171 C  C   . THR F 1 229 ? 38.287  -0.013  57.000  1.00 38.38  ? 229 THR F C   1 
ATOM   13172 O  O   . THR F 1 229 ? 37.447  0.800   56.643  1.00 40.97  ? 229 THR F O   1 
ATOM   13173 C  CB  . THR F 1 229 ? 39.824  0.483   55.107  1.00 37.18  ? 229 THR F CB  1 
ATOM   13174 O  OG1 . THR F 1 229 ? 39.499  -0.704  54.390  1.00 33.85  ? 229 THR F OG1 1 
ATOM   13175 C  CG2 . THR F 1 229 ? 41.237  0.885   54.739  1.00 46.80  ? 229 THR F CG2 1 
ATOM   13176 N  N   . SER F 1 230 ? 38.008  -1.123  57.711  1.00 40.12  ? 230 SER F N   1 
ATOM   13177 C  CA  . SER F 1 230 ? 36.776  -1.273  58.494  1.00 40.25  ? 230 SER F CA  1 
ATOM   13178 C  C   . SER F 1 230 ? 36.964  -0.623  59.858  1.00 40.86  ? 230 SER F C   1 
ATOM   13179 O  O   . SER F 1 230 ? 37.885  -0.921  60.586  1.00 43.86  ? 230 SER F O   1 
ATOM   13180 C  CB  . SER F 1 230 ? 36.353  -2.681  58.679  1.00 35.54  ? 230 SER F CB  1 
ATOM   13181 O  OG  . SER F 1 230 ? 36.126  -3.236  57.405  1.00 32.77  ? 230 SER F OG  1 
ATOM   13182 N  N   . VAL F 1 231 ? 36.117  0.343   60.152  1.00 45.55  ? 231 VAL F N   1 
ATOM   13183 C  CA  . VAL F 1 231 ? 36.198  1.086   61.385  1.00 49.99  ? 231 VAL F CA  1 
ATOM   13184 C  C   . VAL F 1 231 ? 34.777  1.205   61.918  1.00 54.86  ? 231 VAL F C   1 
ATOM   13185 O  O   . VAL F 1 231 ? 33.822  1.445   61.173  1.00 49.52  ? 231 VAL F O   1 
ATOM   13186 C  CB  . VAL F 1 231 ? 36.862  2.442   61.104  1.00 54.68  ? 231 VAL F CB  1 
ATOM   13187 C  CG1 . VAL F 1 231 ? 36.515  3.503   62.141  1.00 52.66  ? 231 VAL F CG1 1 
ATOM   13188 C  CG2 . VAL F 1 231 ? 38.361  2.240   60.972  1.00 57.67  ? 231 VAL F CG2 1 
ATOM   13189 N  N   . THR F 1 232 ? 34.647  0.930   63.214  1.00 64.67  ? 232 THR F N   1 
ATOM   13190 C  CA  . THR F 1 232 ? 33.387  1.129   63.901  1.00 71.23  ? 232 THR F CA  1 
ATOM   13191 C  C   . THR F 1 232 ? 33.579  2.347   64.792  1.00 75.67  ? 232 THR F C   1 
ATOM   13192 O  O   . THR F 1 232 ? 34.675  2.579   65.306  1.00 65.05  ? 232 THR F O   1 
ATOM   13193 C  CB  . THR F 1 232 ? 32.981  -0.121  64.678  1.00 69.81  ? 232 THR F CB  1 
ATOM   13194 O  OG1 . THR F 1 232 ? 34.229  -0.323  65.331  1.00 60.98  ? 232 THR F OG1 1 
ATOM   13195 C  CG2 . THR F 1 232 ? 32.545  -1.270  63.778  1.00 68.36  ? 232 THR F CG2 1 
ATOM   13196 N  N   . GLY F 1 233 ? 32.525  3.162   64.880  1.00 85.05  ? 233 GLY F N   1 
ATOM   13197 C  CA  . GLY F 1 233 ? 32.618  4.381   65.648  1.00 96.34  ? 233 GLY F CA  1 
ATOM   13198 C  C   . GLY F 1 233 ? 32.613  4.020   67.128  1.00 109.63 ? 233 GLY F C   1 
ATOM   13199 O  O   . GLY F 1 233 ? 32.298  2.870   67.472  1.00 84.40  ? 233 GLY F O   1 
ATOM   13200 N  N   . PRO F 1 234 ? 32.966  4.976   68.030  1.00 116.99 ? 234 PRO F N   1 
ATOM   13201 C  CA  . PRO F 1 234 ? 32.359  4.986   69.364  1.00 105.78 ? 234 PRO F CA  1 
ATOM   13202 C  C   . PRO F 1 234 ? 30.886  4.519   69.380  1.00 109.76 ? 234 PRO F C   1 
ATOM   13203 O  O   . PRO F 1 234 ? 30.553  3.689   70.224  1.00 93.03  ? 234 PRO F O   1 
ATOM   13204 C  CB  . PRO F 1 234 ? 32.606  6.470   69.740  1.00 95.03  ? 234 PRO F CB  1 
ATOM   13205 C  CG  . PRO F 1 234 ? 33.990  6.788   69.156  1.00 83.92  ? 234 PRO F CG  1 
ATOM   13206 C  CD  . PRO F 1 234 ? 33.968  6.053   67.828  1.00 97.39  ? 234 PRO F CD  1 
ATOM   13207 N  N   . ASP F 1 235 ? 30.062  4.956   68.385  1.00 115.29 ? 235 ASP F N   1 
ATOM   13208 C  CA  . ASP F 1 235 ? 28.655  4.590   68.148  1.00 92.61  ? 235 ASP F CA  1 
ATOM   13209 C  C   . ASP F 1 235 ? 28.377  3.070   68.196  1.00 87.92  ? 235 ASP F C   1 
ATOM   13210 O  O   . ASP F 1 235 ? 27.276  2.680   68.560  1.00 69.73  ? 235 ASP F O   1 
ATOM   13211 C  CB  . ASP F 1 235 ? 28.121  5.250   66.867  1.00 59.61  ? 235 ASP F CB  1 
ATOM   13212 N  N   . GLY F 1 236 ? 29.331  2.192   67.816  1.00 95.35  ? 236 GLY F N   1 
ATOM   13213 C  CA  . GLY F 1 236 ? 29.049  0.773   67.578  1.00 77.59  ? 236 GLY F CA  1 
ATOM   13214 C  C   . GLY F 1 236 ? 28.794  0.493   66.089  1.00 79.58  ? 236 GLY F C   1 
ATOM   13215 O  O   . GLY F 1 236 ? 29.058  -0.599  65.592  1.00 62.56  ? 236 GLY F O   1 
ATOM   13216 N  N   . SER F 1 237 ? 28.260  1.510   65.395  1.00 85.74  ? 237 SER F N   1 
ATOM   13217 C  CA  . SER F 1 237 ? 27.989  1.513   63.965  1.00 75.90  ? 237 SER F CA  1 
ATOM   13218 C  C   . SER F 1 237 ? 29.288  1.655   63.167  1.00 72.35  ? 237 SER F C   1 
ATOM   13219 O  O   . SER F 1 237 ? 30.229  2.317   63.615  1.00 58.74  ? 237 SER F O   1 
ATOM   13220 C  CB  . SER F 1 237 ? 27.043  2.652   63.651  1.00 73.54  ? 237 SER F CB  1 
ATOM   13221 O  OG  . SER F 1 237 ? 27.380  3.764   64.478  1.00 88.73  ? 237 SER F OG  1 
ATOM   13222 N  N   . ASP F 1 238 ? 29.297  1.021   61.983  1.00 64.90  ? 238 ASP F N   1 
ATOM   13223 C  CA  . ASP F 1 238 ? 30.240  1.254   60.895  1.00 60.91  ? 238 ASP F CA  1 
ATOM   13224 C  C   . ASP F 1 238 ? 30.420  2.743   60.538  1.00 53.68  ? 238 ASP F C   1 
ATOM   13225 O  O   . ASP F 1 238 ? 29.443  3.488   60.403  1.00 49.25  ? 238 ASP F O   1 
ATOM   13226 C  CB  . ASP F 1 238 ? 29.729  0.550   59.645  1.00 68.64  ? 238 ASP F CB  1 
ATOM   13227 C  CG  . ASP F 1 238 ? 29.710  -0.968  59.686  1.00 69.56  ? 238 ASP F CG  1 
ATOM   13228 O  OD1 . ASP F 1 238 ? 29.892  -1.520  60.777  1.00 70.56  ? 238 ASP F OD1 1 
ATOM   13229 O  OD2 . ASP F 1 238 ? 29.565  -1.571  58.611  1.00 71.71  ? 238 ASP F OD2 1 
ATOM   13230 N  N   . LEU F 1 239 ? 31.688  3.161   60.347  1.00 46.58  ? 239 LEU F N   1 
ATOM   13231 C  CA  . LEU F 1 239 ? 32.046  4.435   59.738  1.00 48.57  ? 239 LEU F CA  1 
ATOM   13232 C  C   . LEU F 1 239 ? 32.444  4.285   58.258  1.00 41.33  ? 239 LEU F C   1 
ATOM   13233 O  O   . LEU F 1 239 ? 33.344  3.533   57.895  1.00 40.67  ? 239 LEU F O   1 
ATOM   13234 C  CB  . LEU F 1 239 ? 33.180  5.052   60.548  1.00 42.98  ? 239 LEU F CB  1 
ATOM   13235 C  CG  . LEU F 1 239 ? 32.729  5.630   61.891  1.00 46.29  ? 239 LEU F CG  1 
ATOM   13236 C  CD1 . LEU F 1 239 ? 33.980  6.285   62.420  1.00 48.16  ? 239 LEU F CD1 1 
ATOM   13237 C  CD2 . LEU F 1 239 ? 31.554  6.621   61.903  1.00 43.24  ? 239 LEU F CD2 1 
ATOM   13238 N  N   . GLU F 1 240 ? 31.780  5.056   57.403  1.00 33.09  ? 240 GLU F N   1 
ATOM   13239 C  CA  . GLU F 1 240 ? 31.845  4.844   55.978  1.00 33.52  ? 240 GLU F CA  1 
ATOM   13240 C  C   . GLU F 1 240 ? 32.348  6.115   55.304  1.00 32.38  ? 240 GLU F C   1 
ATOM   13241 O  O   . GLU F 1 240 ? 32.030  7.251   55.714  1.00 28.92  ? 240 GLU F O   1 
ATOM   13242 C  CB  . GLU F 1 240 ? 30.443  4.476   55.471  1.00 39.46  ? 240 GLU F CB  1 
ATOM   13243 C  CG  . GLU F 1 240 ? 29.884  3.187   56.071  1.00 41.50  ? 240 GLU F CG  1 
ATOM   13244 C  CD  . GLU F 1 240 ? 29.048  2.404   55.092  1.00 46.69  ? 240 GLU F CD  1 
ATOM   13245 O  OE1 . GLU F 1 240 ? 27.871  2.760   55.203  1.00 44.39  ? 240 GLU F OE1 1 
ATOM   13246 O  OE2 . GLU F 1 240 ? 29.523  1.553   54.258  1.00 49.47  ? 240 GLU F OE2 1 
ATOM   13247 N  N   . ILE F 1 241 ? 33.114  5.881   54.229  1.00 34.19  ? 241 ILE F N   1 
ATOM   13248 C  CA  . ILE F 1 241 ? 33.445  6.923   53.266  1.00 31.10  ? 241 ILE F CA  1 
ATOM   13249 C  C   . ILE F 1 241 ? 32.932  6.503   51.886  1.00 27.13  ? 241 ILE F C   1 
ATOM   13250 O  O   . ILE F 1 241 ? 32.478  5.367   51.667  1.00 23.28  ? 241 ILE F O   1 
ATOM   13251 C  CB  . ILE F 1 241 ? 34.954  7.234   53.244  1.00 27.69  ? 241 ILE F CB  1 
ATOM   13252 C  CG1 . ILE F 1 241 ? 35.742  6.041   52.734  1.00 28.31  ? 241 ILE F CG1 1 
ATOM   13253 C  CG2 . ILE F 1 241 ? 35.427  7.682   54.626  1.00 27.46  ? 241 ILE F CG2 1 
ATOM   13254 C  CD1 . ILE F 1 241 ? 37.185  6.363   52.456  1.00 28.87  ? 241 ILE F CD1 1 
ATOM   13255 N  N   . LEU F 1 242 ? 32.996  7.478   50.976  1.00 23.90  ? 242 LEU F N   1 
ATOM   13256 C  CA  . LEU F 1 242 ? 32.557  7.283   49.610  1.00 24.00  ? 242 LEU F CA  1 
ATOM   13257 C  C   . LEU F 1 242 ? 33.763  7.482   48.733  1.00 22.72  ? 242 LEU F C   1 
ATOM   13258 O  O   . LEU F 1 242 ? 34.270  8.585   48.680  1.00 22.79  ? 242 LEU F O   1 
ATOM   13259 C  CB  . LEU F 1 242 ? 31.468  8.266   49.201  1.00 22.30  ? 242 LEU F CB  1 
ATOM   13260 C  CG  . LEU F 1 242 ? 30.930  8.091   47.778  1.00 22.80  ? 242 LEU F CG  1 
ATOM   13261 C  CD1 . LEU F 1 242 ? 30.211  6.795   47.624  1.00 24.07  ? 242 LEU F CD1 1 
ATOM   13262 C  CD2 . LEU F 1 242 ? 30.006  9.209   47.384  1.00 24.83  ? 242 LEU F CD2 1 
ATOM   13263 N  N   . ARG F 1 243 ? 34.160  6.417   48.041  1.00 22.30  ? 243 ARG F N   1 
ATOM   13264 C  CA  . ARG F 1 243 ? 35.354  6.436   47.225  1.00 24.05  ? 243 ARG F CA  1 
ATOM   13265 C  C   . ARG F 1 243 ? 34.964  6.402   45.749  1.00 28.23  ? 243 ARG F C   1 
ATOM   13266 O  O   . ARG F 1 243 ? 33.871  5.911   45.428  1.00 25.98  ? 243 ARG F O   1 
ATOM   13267 C  CB  . ARG F 1 243 ? 36.214  5.203   47.518  1.00 24.19  ? 243 ARG F CB  1 
ATOM   13268 C  CG  . ARG F 1 243 ? 36.857  5.183   48.893  1.00 23.15  ? 243 ARG F CG  1 
ATOM   13269 C  CD  . ARG F 1 243 ? 37.264  3.776   49.230  1.00 25.43  ? 243 ARG F CD  1 
ATOM   13270 N  NE  . ARG F 1 243 ? 36.084  2.905   49.425  1.00 29.42  ? 243 ARG F NE  1 
ATOM   13271 C  CZ  . ARG F 1 243 ? 35.888  1.740   48.747  1.00 29.75  ? 243 ARG F CZ  1 
ATOM   13272 N  NH1 . ARG F 1 243 ? 36.800  1.280   47.916  1.00 29.64  ? 243 ARG F NH1 1 
ATOM   13273 N  NH2 . ARG F 1 243 ? 34.812  1.004   48.906  1.00 29.10  ? 243 ARG F NH2 1 
ATOM   13274 N  N   . ASP F 1 244 ? 35.843  6.958   44.887  1.00 28.16  ? 244 ASP F N   1 
ATOM   13275 C  CA  . ASP F 1 244 ? 35.700  6.870   43.445  1.00 26.73  ? 244 ASP F CA  1 
ATOM   13276 C  C   . ASP F 1 244 ? 37.098  6.739   42.821  1.00 27.44  ? 244 ASP F C   1 
ATOM   13277 O  O   . ASP F 1 244 ? 37.519  7.571   42.013  1.00 26.56  ? 244 ASP F O   1 
ATOM   13278 C  CB  . ASP F 1 244 ? 34.851  8.024   42.911  1.00 24.66  ? 244 ASP F CB  1 
ATOM   13279 C  CG  . ASP F 1 244 ? 34.167  7.703   41.591  1.00 27.16  ? 244 ASP F CG  1 
ATOM   13280 O  OD1 . ASP F 1 244 ? 34.335  6.547   41.103  1.00 25.93  ? 244 ASP F OD1 1 
ATOM   13281 O  OD2 . ASP F 1 244 ? 33.506  8.595   41.030  1.00 32.42  ? 244 ASP F OD2 1 
ATOM   13282 N  N   . ASN F 1 245 ? 37.823  5.699   43.229  1.00 27.21  ? 245 ASN F N   1 
ATOM   13283 C  CA  . ASN F 1 245 ? 39.193  5.470   42.789  1.00 26.69  ? 245 ASN F CA  1 
ATOM   13284 C  C   . ASN F 1 245 ? 39.229  5.208   41.277  1.00 24.39  ? 245 ASN F C   1 
ATOM   13285 O  O   . ASN F 1 245 ? 38.363  4.541   40.725  1.00 25.55  ? 245 ASN F O   1 
ATOM   13286 C  CB  . ASN F 1 245 ? 39.795  4.270   43.510  1.00 29.38  ? 245 ASN F CB  1 
ATOM   13287 C  CG  . ASN F 1 245 ? 39.816  4.444   45.013  1.00 32.60  ? 245 ASN F CG  1 
ATOM   13288 O  OD1 . ASN F 1 245 ? 39.598  5.552   45.526  1.00 29.00  ? 245 ASN F OD1 1 
ATOM   13289 N  ND2 . ASN F 1 245 ? 40.107  3.355   45.718  1.00 37.63  ? 245 ASN F ND2 1 
ATOM   13290 N  N   . MET F 1 246 ? 40.210  5.795   40.605  1.00 23.30  ? 246 MET F N   1 
ATOM   13291 C  CA  . MET F 1 246 ? 40.345  5.738   39.159  1.00 23.63  ? 246 MET F CA  1 
ATOM   13292 C  C   . MET F 1 246 ? 41.748  5.254   38.820  1.00 21.45  ? 246 MET F C   1 
ATOM   13293 O  O   . MET F 1 246 ? 42.744  5.852   39.220  1.00 22.26  ? 246 MET F O   1 
ATOM   13294 C  CB  . MET F 1 246 ? 40.097  7.092   38.478  1.00 26.05  ? 246 MET F CB  1 
ATOM   13295 C  CG  . MET F 1 246 ? 38.640  7.507   38.436  1.00 29.01  ? 246 MET F CG  1 
ATOM   13296 S  SD  . MET F 1 246 ? 37.519  6.306   37.677  1.00 30.33  ? 246 MET F SD  1 
ATOM   13297 C  CE  . MET F 1 246 ? 37.757  7.051   36.082  1.00 32.22  ? 246 MET F CE  1 
ATOM   13298 N  N   . PRO F 1 247 ? 41.861  4.170   38.043  1.00 18.89  ? 247 PRO F N   1 
ATOM   13299 C  CA  . PRO F 1 247 ? 43.119  3.819   37.433  1.00 21.60  ? 247 PRO F CA  1 
ATOM   13300 C  C   . PRO F 1 247 ? 43.590  4.930   36.489  1.00 25.66  ? 247 PRO F C   1 
ATOM   13301 O  O   . PRO F 1 247 ? 42.780  5.640   35.872  1.00 25.71  ? 247 PRO F O   1 
ATOM   13302 C  CB  . PRO F 1 247 ? 42.772  2.536   36.647  1.00 21.03  ? 247 PRO F CB  1 
ATOM   13303 C  CG  . PRO F 1 247 ? 41.462  2.059   37.151  1.00 19.74  ? 247 PRO F CG  1 
ATOM   13304 C  CD  . PRO F 1 247 ? 40.764  3.276   37.659  1.00 19.35  ? 247 PRO F CD  1 
ATOM   13305 N  N   . PHE F 1 248 ? 44.914  5.034   36.343  1.00 29.15  ? 248 PHE F N   1 
ATOM   13306 C  CA  . PHE F 1 248 ? 45.531  5.918   35.358  1.00 28.47  ? 248 PHE F CA  1 
ATOM   13307 C  C   . PHE F 1 248 ? 46.894  5.335   35.024  1.00 29.42  ? 248 PHE F C   1 
ATOM   13308 O  O   . PHE F 1 248 ? 47.382  4.463   35.750  1.00 27.40  ? 248 PHE F O   1 
ATOM   13309 C  CB  . PHE F 1 248 ? 45.662  7.346   35.889  1.00 26.27  ? 248 PHE F CB  1 
ATOM   13310 C  CG  . PHE F 1 248 ? 46.689  7.462   37.001  1.00 26.65  ? 248 PHE F CG  1 
ATOM   13311 C  CD1 . PHE F 1 248 ? 48.041  7.622   36.719  1.00 24.62  ? 248 PHE F CD1 1 
ATOM   13312 C  CD2 . PHE F 1 248 ? 46.303  7.330   38.323  1.00 28.65  ? 248 PHE F CD2 1 
ATOM   13313 C  CE1 . PHE F 1 248 ? 48.977  7.702   37.722  1.00 24.96  ? 248 PHE F CE1 1 
ATOM   13314 C  CE2 . PHE F 1 248 ? 47.252  7.417   39.328  1.00 29.16  ? 248 PHE F CE2 1 
ATOM   13315 C  CZ  . PHE F 1 248 ? 48.583  7.629   39.028  1.00 26.11  ? 248 PHE F CZ  1 
ATOM   13316 N  N   . GLY F 1 249 ? 47.523  5.806   33.947  1.00 29.59  ? 249 GLY F N   1 
ATOM   13317 C  CA  . GLY F 1 249 ? 48.914  5.427   33.789  1.00 28.88  ? 249 GLY F CA  1 
ATOM   13318 C  C   . GLY F 1 249 ? 49.478  5.716   32.413  1.00 28.50  ? 249 GLY F C   1 
ATOM   13319 O  O   . GLY F 1 249 ? 48.848  6.332   31.560  1.00 25.23  ? 249 GLY F O   1 
ATOM   13320 N  N   . SER F 1 250 ? 50.698  5.218   32.229  1.00 33.58  ? 250 SER F N   1 
ATOM   13321 C  CA  . SER F 1 250 ? 51.429  5.376   30.993  1.00 33.23  ? 250 SER F CA  1 
ATOM   13322 C  C   . SER F 1 250 ? 52.286  4.135   30.786  1.00 32.66  ? 250 SER F C   1 
ATOM   13323 O  O   . SER F 1 250 ? 53.052  3.773   31.676  1.00 34.69  ? 250 SER F O   1 
ATOM   13324 C  CB  . SER F 1 250 ? 52.231  6.616   31.079  1.00 35.48  ? 250 SER F CB  1 
ATOM   13325 O  OG  . SER F 1 250 ? 53.311  6.517   30.168  1.00 48.07  ? 250 SER F OG  1 
ATOM   13326 N  N   . VAL F 1 251 ? 52.120  3.437   29.665  1.00 29.32  ? 251 VAL F N   1 
ATOM   13327 C  CA  . VAL F 1 251 ? 52.734  2.134   29.524  1.00 33.81  ? 251 VAL F CA  1 
ATOM   13328 C  C   . VAL F 1 251 ? 54.206  2.338   29.222  1.00 37.52  ? 251 VAL F C   1 
ATOM   13329 O  O   . VAL F 1 251 ? 55.061  1.581   29.670  1.00 36.85  ? 251 VAL F O   1 
ATOM   13330 C  CB  . VAL F 1 251 ? 52.077  1.309   28.421  1.00 42.51  ? 251 VAL F CB  1 
ATOM   13331 C  CG1 . VAL F 1 251 ? 52.374  -0.166  28.574  1.00 53.51  ? 251 VAL F CG1 1 
ATOM   13332 C  CG2 . VAL F 1 251 ? 50.582  1.446   28.488  1.00 51.69  ? 251 VAL F CG2 1 
ATOM   13333 N  N   . GLY F 1 252 ? 54.483  3.358   28.422  1.00 38.46  ? 252 GLY F N   1 
ATOM   13334 C  CA  . GLY F 1 252 ? 55.844  3.706   28.083  1.00 38.48  ? 252 GLY F CA  1 
ATOM   13335 C  C   . GLY F 1 252 ? 56.663  3.995   29.326  1.00 34.49  ? 252 GLY F C   1 
ATOM   13336 O  O   . GLY F 1 252 ? 57.804  3.578   29.366  1.00 38.53  ? 252 GLY F O   1 
ATOM   13337 N  N   . ARG F 1 253 ? 56.104  4.701   30.312  1.00 32.09  ? 253 ARG F N   1 
ATOM   13338 C  CA  . ARG F 1 253 ? 56.862  5.143   31.481  1.00 35.92  ? 253 ARG F CA  1 
ATOM   13339 C  C   . ARG F 1 253 ? 56.770  4.127   32.612  1.00 36.95  ? 253 ARG F C   1 
ATOM   13340 O  O   . ARG F 1 253 ? 57.246  4.359   33.703  1.00 44.06  ? 253 ARG F O   1 
ATOM   13341 C  CB  . ARG F 1 253 ? 56.377  6.493   32.014  1.00 37.02  ? 253 ARG F CB  1 
ATOM   13342 C  CG  . ARG F 1 253 ? 56.616  7.579   30.979  1.00 48.26  ? 253 ARG F CG  1 
ATOM   13343 C  CD  . ARG F 1 253 ? 57.009  8.920   31.617  1.00 62.14  ? 253 ARG F CD  1 
ATOM   13344 N  NE  . ARG F 1 253 ? 55.948  9.354   32.521  1.00 72.88  ? 253 ARG F NE  1 
ATOM   13345 C  CZ  . ARG F 1 253 ? 54.725  9.656   32.086  1.00 86.35  ? 253 ARG F CZ  1 
ATOM   13346 N  NH1 . ARG F 1 253 ? 54.504  9.886   30.794  1.00 86.83  ? 253 ARG F NH1 1 
ATOM   13347 N  NH2 . ARG F 1 253 ? 53.731  9.761   32.953  1.00 90.41  ? 253 ARG F NH2 1 
ATOM   13348 N  N   . GLU F 1 254 ? 56.137  2.990   32.351  1.00 39.33  ? 254 GLU F N   1 
ATOM   13349 C  CA  . GLU F 1 254 ? 55.866  1.995   33.369  1.00 39.31  ? 254 GLU F CA  1 
ATOM   13350 C  C   . GLU F 1 254 ? 55.144  2.602   34.585  1.00 34.28  ? 254 GLU F C   1 
ATOM   13351 O  O   . GLU F 1 254 ? 55.353  2.126   35.667  1.00 36.60  ? 254 GLU F O   1 
ATOM   13352 C  CB  . GLU F 1 254 ? 57.219  1.316   33.604  1.00 44.92  ? 254 GLU F CB  1 
ATOM   13353 C  CG  . GLU F 1 254 ? 57.112  -0.204  33.680  1.00 56.00  ? 254 GLU F CG  1 
ATOM   13354 C  CD  . GLU F 1 254 ? 58.396  -0.942  34.030  1.00 69.60  ? 254 GLU F CD  1 
ATOM   13355 O  OE1 . GLU F 1 254 ? 59.400  -0.768  33.310  1.00 86.06  ? 254 GLU F OE1 1 
ATOM   13356 O  OE2 . GLU F 1 254 ? 58.391  -1.715  35.014  1.00 73.88  ? 254 GLU F OE2 1 
ATOM   13357 N  N   . GLU F 1 255 ? 54.256  3.595   34.442  1.00 32.56  ? 255 GLU F N   1 
ATOM   13358 C  CA  . GLU F 1 255 ? 53.431  4.059   35.539  1.00 30.85  ? 255 GLU F CA  1 
ATOM   13359 C  C   . GLU F 1 255 ? 52.050  3.407   35.515  1.00 34.74  ? 255 GLU F C   1 
ATOM   13360 O  O   . GLU F 1 255 ? 51.287  3.560   34.557  1.00 27.20  ? 255 GLU F O   1 
ATOM   13361 C  CB  . GLU F 1 255 ? 53.074  5.524   35.454  1.00 31.47  ? 255 GLU F CB  1 
ATOM   13362 C  CG  . GLU F 1 255 ? 54.311  6.381   35.447  1.00 38.68  ? 255 GLU F CG  1 
ATOM   13363 C  CD  . GLU F 1 255 ? 53.848  7.801   35.571  1.00 48.93  ? 255 GLU F CD  1 
ATOM   13364 O  OE1 . GLU F 1 255 ? 52.648  8.046   35.870  1.00 52.11  ? 255 GLU F OE1 1 
ATOM   13365 O  OE2 . GLU F 1 255 ? 54.746  8.641   35.363  1.00 52.97  ? 255 GLU F OE2 1 
ATOM   13366 N  N   . PHE F 1 256 ? 51.743  2.673   36.598  1.00 33.20  ? 256 PHE F N   1 
ATOM   13367 C  CA  . PHE F 1 256 ? 50.423  2.112   36.762  1.00 31.56  ? 256 PHE F CA  1 
ATOM   13368 C  C   . PHE F 1 256 ? 49.901  2.597   38.091  1.00 29.42  ? 256 PHE F C   1 
ATOM   13369 O  O   . PHE F 1 256 ? 50.524  2.337   39.086  1.00 32.16  ? 256 PHE F O   1 
ATOM   13370 C  CB  . PHE F 1 256 ? 50.518  0.596   36.714  1.00 35.73  ? 256 PHE F CB  1 
ATOM   13371 C  CG  . PHE F 1 256 ? 51.163  0.057   35.452  1.00 38.52  ? 256 PHE F CG  1 
ATOM   13372 C  CD1 . PHE F 1 256 ? 50.415  -0.190  34.323  1.00 42.64  ? 256 PHE F CD1 1 
ATOM   13373 C  CD2 . PHE F 1 256 ? 52.516  -0.217  35.407  1.00 43.89  ? 256 PHE F CD2 1 
ATOM   13374 C  CE1 . PHE F 1 256 ? 51.005  -0.710  33.181  1.00 46.91  ? 256 PHE F CE1 1 
ATOM   13375 C  CE2 . PHE F 1 256 ? 53.108  -0.738  34.263  1.00 44.43  ? 256 PHE F CE2 1 
ATOM   13376 C  CZ  . PHE F 1 256 ? 52.353  -0.980  33.153  1.00 46.11  ? 256 PHE F CZ  1 
ATOM   13377 N  N   . GLY F 1 257 ? 48.762  3.275   38.098  1.00 28.71  ? 257 GLY F N   1 
ATOM   13378 C  CA  . GLY F 1 257 ? 48.376  4.058   39.248  1.00 27.00  ? 257 GLY F CA  1 
ATOM   13379 C  C   . GLY F 1 257 ? 46.911  3.858   39.631  1.00 24.72  ? 257 GLY F C   1 
ATOM   13380 O  O   . GLY F 1 257 ? 46.108  3.296   38.868  1.00 24.17  ? 257 GLY F O   1 
ATOM   13381 N  N   . THR F 1 258 ? 46.628  4.272   40.874  1.00 22.01  ? 258 THR F N   1 
ATOM   13382 C  CA  . THR F 1 258 ? 45.282  4.391   41.386  1.00 21.43  ? 258 THR F CA  1 
ATOM   13383 C  C   . THR F 1 258 ? 45.168  5.779   41.974  1.00 20.97  ? 258 THR F C   1 
ATOM   13384 O  O   . THR F 1 258 ? 45.988  6.150   42.794  1.00 22.06  ? 258 THR F O   1 
ATOM   13385 C  CB  . THR F 1 258 ? 45.015  3.311   42.434  1.00 23.58  ? 258 THR F CB  1 
ATOM   13386 O  OG1 . THR F 1 258 ? 44.905  2.051   41.737  1.00 25.45  ? 258 THR F OG1 1 
ATOM   13387 C  CG2 . THR F 1 258 ? 43.746  3.660   43.206  1.00 25.52  ? 258 THR F CG2 1 
ATOM   13388 N  N   . TYR F 1 259 ? 44.224  6.568   41.487  1.00 20.13  ? 259 TYR F N   1 
ATOM   13389 C  CA  . TYR F 1 259 ? 43.961  7.889   42.021  1.00 20.23  ? 259 TYR F CA  1 
ATOM   13390 C  C   . TYR F 1 259 ? 42.870  7.712   43.062  1.00 22.85  ? 259 TYR F C   1 
ATOM   13391 O  O   . TYR F 1 259 ? 41.718  7.436   42.747  1.00 23.04  ? 259 TYR F O   1 
ATOM   13392 C  CB  . TYR F 1 259 ? 43.607  8.924   40.940  1.00 20.35  ? 259 TYR F CB  1 
ATOM   13393 C  CG  . TYR F 1 259 ? 43.825  10.350  41.419  1.00 20.22  ? 259 TYR F CG  1 
ATOM   13394 C  CD1 . TYR F 1 259 ? 42.889  10.980  42.217  1.00 21.01  ? 259 TYR F CD1 1 
ATOM   13395 C  CD2 . TYR F 1 259 ? 44.998  11.031  41.138  1.00 22.12  ? 259 TYR F CD2 1 
ATOM   13396 C  CE1 . TYR F 1 259 ? 43.087  12.268  42.680  1.00 22.71  ? 259 TYR F CE1 1 
ATOM   13397 C  CE2 . TYR F 1 259 ? 45.212  12.316  41.596  1.00 24.67  ? 259 TYR F CE2 1 
ATOM   13398 C  CZ  . TYR F 1 259 ? 44.258  12.954  42.376  1.00 27.65  ? 259 TYR F CZ  1 
ATOM   13399 O  OH  . TYR F 1 259 ? 44.516  14.240  42.840  1.00 27.63  ? 259 TYR F OH  1 
ATOM   13400 N  N   . PHE F 1 260 ? 43.262  7.841   44.330  1.00 26.62  ? 260 PHE F N   1 
ATOM   13401 C  CA  . PHE F 1 260 ? 42.348  7.715   45.453  1.00 27.60  ? 260 PHE F CA  1 
ATOM   13402 C  C   . PHE F 1 260 ? 41.643  9.048   45.668  1.00 26.00  ? 260 PHE F C   1 
ATOM   13403 O  O   . PHE F 1 260 ? 42.285  10.078  45.773  1.00 22.99  ? 260 PHE F O   1 
ATOM   13404 C  CB  . PHE F 1 260 ? 43.116  7.313   46.726  1.00 26.49  ? 260 PHE F CB  1 
ATOM   13405 C  CG  . PHE F 1 260 ? 42.224  7.316   47.949  1.00 25.34  ? 260 PHE F CG  1 
ATOM   13406 C  CD1 . PHE F 1 260 ? 41.358  6.245   48.185  1.00 25.31  ? 260 PHE F CD1 1 
ATOM   13407 C  CD2 . PHE F 1 260 ? 42.214  8.415   48.800  1.00 25.11  ? 260 PHE F CD2 1 
ATOM   13408 C  CE1 . PHE F 1 260 ? 40.511  6.269   49.283  1.00 24.65  ? 260 PHE F CE1 1 
ATOM   13409 C  CE2 . PHE F 1 260 ? 41.334  8.462   49.870  1.00 25.80  ? 260 PHE F CE2 1 
ATOM   13410 C  CZ  . PHE F 1 260 ? 40.492  7.387   50.121  1.00 23.74  ? 260 PHE F CZ  1 
ATOM   13411 N  N   . ILE F 1 261 ? 40.322  9.001   45.775  1.00 27.06  ? 261 ILE F N   1 
ATOM   13412 C  CA  . ILE F 1 261 ? 39.586  10.133  46.293  1.00 26.04  ? 261 ILE F CA  1 
ATOM   13413 C  C   . ILE F 1 261 ? 38.498  9.545   47.175  1.00 26.19  ? 261 ILE F C   1 
ATOM   13414 O  O   . ILE F 1 261 ? 37.806  8.613   46.758  1.00 25.00  ? 261 ILE F O   1 
ATOM   13415 C  CB  . ILE F 1 261 ? 39.014  11.053  45.190  1.00 27.36  ? 261 ILE F CB  1 
ATOM   13416 C  CG1 . ILE F 1 261 ? 38.340  12.270  45.800  1.00 29.49  ? 261 ILE F CG1 1 
ATOM   13417 C  CG2 . ILE F 1 261 ? 38.031  10.319  44.262  1.00 27.67  ? 261 ILE F CG2 1 
ATOM   13418 C  CD1 . ILE F 1 261 ? 38.050  13.355  44.787  1.00 29.59  ? 261 ILE F CD1 1 
ATOM   13419 N  N   . GLY F 1 262 ? 38.392  10.102  48.388  1.00 26.11  ? 262 GLY F N   1 
ATOM   13420 C  CA  . GLY F 1 262 ? 37.378  9.719   49.350  1.00 25.99  ? 262 GLY F CA  1 
ATOM   13421 C  C   . GLY F 1 262 ? 36.650  10.926  49.936  1.00 24.82  ? 262 GLY F C   1 
ATOM   13422 O  O   . GLY F 1 262 ? 37.258  11.834  50.514  1.00 26.50  ? 262 GLY F O   1 
ATOM   13423 N  N   . TYR F 1 263 ? 35.323  10.870  49.857  1.00 21.88  ? 263 TYR F N   1 
ATOM   13424 C  CA  . TYR F 1 263 ? 34.537  11.890  50.495  1.00 23.25  ? 263 TYR F CA  1 
ATOM   13425 C  C   . TYR F 1 263 ? 34.008  11.385  51.830  1.00 27.09  ? 263 TYR F C   1 
ATOM   13426 O  O   . TYR F 1 263 ? 33.646  10.216  51.918  1.00 29.78  ? 263 TYR F O   1 
ATOM   13427 C  CB  . TYR F 1 263 ? 33.397  12.195  49.553  1.00 21.87  ? 263 TYR F CB  1 
ATOM   13428 C  CG  . TYR F 1 263 ? 33.788  12.886  48.260  1.00 22.71  ? 263 TYR F CG  1 
ATOM   13429 C  CD1 . TYR F 1 263 ? 33.766  14.267  48.186  1.00 23.05  ? 263 TYR F CD1 1 
ATOM   13430 C  CD2 . TYR F 1 263 ? 34.083  12.174  47.100  1.00 23.79  ? 263 TYR F CD2 1 
ATOM   13431 C  CE1 . TYR F 1 263 ? 34.051  14.935  47.012  1.00 24.35  ? 263 TYR F CE1 1 
ATOM   13432 C  CE2 . TYR F 1 263 ? 34.400  12.829  45.921  1.00 23.72  ? 263 TYR F CE2 1 
ATOM   13433 C  CZ  . TYR F 1 263 ? 34.374  14.213  45.883  1.00 23.42  ? 263 TYR F CZ  1 
ATOM   13434 O  OH  . TYR F 1 263 ? 34.622  14.955  44.768  1.00 27.25  ? 263 TYR F OH  1 
ATOM   13435 N  N   . ALA F 1 264 ? 33.985  12.269  52.846  1.00 29.00  ? 264 ALA F N   1 
ATOM   13436 C  CA  . ALA F 1 264 ? 33.325  12.040  54.134  1.00 26.73  ? 264 ALA F CA  1 
ATOM   13437 C  C   . ALA F 1 264 ? 32.748  13.359  54.718  1.00 27.12  ? 264 ALA F C   1 
ATOM   13438 O  O   . ALA F 1 264 ? 33.184  14.454  54.353  1.00 28.93  ? 264 ALA F O   1 
ATOM   13439 C  CB  . ALA F 1 264 ? 34.308  11.324  55.052  1.00 27.14  ? 264 ALA F CB  1 
ATOM   13440 N  N   . ARG F 1 265 ? 31.752  13.275  55.617  1.00 27.04  ? 265 ARG F N   1 
ATOM   13441 C  CA  . ARG F 1 265 ? 31.105  14.449  56.206  1.00 30.04  ? 265 ARG F CA  1 
ATOM   13442 C  C   . ARG F 1 265 ? 32.018  15.121  57.233  1.00 29.44  ? 265 ARG F C   1 
ATOM   13443 O  O   . ARG F 1 265 ? 31.802  16.296  57.552  1.00 26.03  ? 265 ARG F O   1 
ATOM   13444 C  CB  . ARG F 1 265 ? 29.745  14.181  56.866  1.00 37.11  ? 265 ARG F CB  1 
ATOM   13445 C  CG  . ARG F 1 265 ? 29.832  13.453  58.197  1.00 46.86  ? 265 ARG F CG  1 
ATOM   13446 C  CD  . ARG F 1 265 ? 28.482  13.018  58.751  1.00 55.60  ? 265 ARG F CD  1 
ATOM   13447 N  NE  . ARG F 1 265 ? 27.671  14.221  58.934  1.00 55.12  ? 265 ARG F NE  1 
ATOM   13448 C  CZ  . ARG F 1 265 ? 26.363  14.285  59.066  1.00 55.93  ? 265 ARG F CZ  1 
ATOM   13449 N  NH1 . ARG F 1 265 ? 25.585  13.255  58.814  1.00 62.50  ? 265 ARG F NH1 1 
ATOM   13450 N  NH2 . ARG F 1 265 ? 25.813  15.428  59.399  1.00 58.71  ? 265 ARG F NH2 1 
ATOM   13451 N  N   . THR F 1 266 ? 33.025  14.370  57.721  1.00 28.97  ? 266 THR F N   1 
ATOM   13452 C  CA  . THR F 1 266 ? 34.122  14.920  58.509  1.00 30.73  ? 266 THR F CA  1 
ATOM   13453 C  C   . THR F 1 266 ? 35.398  14.207  58.084  1.00 30.28  ? 266 THR F C   1 
ATOM   13454 O  O   . THR F 1 266 ? 35.386  13.007  57.821  1.00 32.25  ? 266 THR F O   1 
ATOM   13455 C  CB  . THR F 1 266 ? 33.883  14.741  60.017  1.00 30.25  ? 266 THR F CB  1 
ATOM   13456 O  OG1 . THR F 1 266 ? 35.076  15.156  60.681  1.00 32.72  ? 266 THR F OG1 1 
ATOM   13457 C  CG2 . THR F 1 266 ? 33.614  13.299  60.425  1.00 27.21  ? 266 THR F CG2 1 
ATOM   13458 N  N   . PRO F 1 267 ? 36.560  14.877  58.093  1.00 28.39  ? 267 PRO F N   1 
ATOM   13459 C  CA  . PRO F 1 267 ? 37.801  14.205  57.740  1.00 28.06  ? 267 PRO F CA  1 
ATOM   13460 C  C   . PRO F 1 267 ? 38.311  13.245  58.796  1.00 31.50  ? 267 PRO F C   1 
ATOM   13461 O  O   . PRO F 1 267 ? 39.239  12.491  58.503  1.00 30.09  ? 267 PRO F O   1 
ATOM   13462 C  CB  . PRO F 1 267 ? 38.826  15.286  57.450  1.00 27.93  ? 267 PRO F CB  1 
ATOM   13463 C  CG  . PRO F 1 267 ? 38.202  16.547  57.984  1.00 29.71  ? 267 PRO F CG  1 
ATOM   13464 C  CD  . PRO F 1 267 ? 36.715  16.318  58.284  1.00 30.50  ? 267 PRO F CD  1 
ATOM   13465 N  N   . GLU F 1 268 ? 37.710  13.272  60.002  1.00 33.04  ? 268 GLU F N   1 
ATOM   13466 C  CA  . GLU F 1 268 ? 38.145  12.401  61.091  1.00 37.06  ? 268 GLU F CA  1 
ATOM   13467 C  C   . GLU F 1 268 ? 38.057  10.943  60.618  1.00 32.42  ? 268 GLU F C   1 
ATOM   13468 O  O   . GLU F 1 268 ? 38.928  10.119  60.922  1.00 25.42  ? 268 GLU F O   1 
ATOM   13469 C  CB  . GLU F 1 268 ? 37.347  12.644  62.376  1.00 45.77  ? 268 GLU F CB  1 
ATOM   13470 C  CG  . GLU F 1 268 ? 37.637  13.960  63.090  1.00 58.33  ? 268 GLU F CG  1 
ATOM   13471 C  CD  . GLU F 1 268 ? 36.930  13.822  64.411  1.00 78.31  ? 268 GLU F CD  1 
ATOM   13472 O  OE1 . GLU F 1 268 ? 35.676  13.752  64.436  1.00 80.50  ? 268 GLU F OE1 1 
ATOM   13473 O  OE2 . GLU F 1 268 ? 37.666  13.685  65.402  1.00 107.71 ? 268 GLU F OE2 1 
ATOM   13474 N  N   . VAL F 1 269 ? 37.026  10.632  59.815  1.00 29.53  ? 269 VAL F N   1 
ATOM   13475 C  CA  . VAL F 1 269 ? 36.799  9.261   59.402  1.00 28.22  ? 269 VAL F CA  1 
ATOM   13476 C  C   . VAL F 1 269 ? 37.911  8.817   58.458  1.00 31.99  ? 269 VAL F C   1 
ATOM   13477 O  O   . VAL F 1 269 ? 38.552  7.761   58.663  1.00 30.02  ? 269 VAL F O   1 
ATOM   13478 C  CB  . VAL F 1 269 ? 35.427  9.122   58.744  1.00 30.03  ? 269 VAL F CB  1 
ATOM   13479 C  CG1 . VAL F 1 269 ? 35.167  7.671   58.373  1.00 30.68  ? 269 VAL F CG1 1 
ATOM   13480 C  CG2 . VAL F 1 269 ? 34.312  9.645   59.638  1.00 31.78  ? 269 VAL F CG2 1 
ATOM   13481 N  N   . THR F 1 270 ? 38.122  9.630   57.405  1.00 29.53  ? 270 THR F N   1 
ATOM   13482 C  CA  . THR F 1 270 ? 39.143  9.335   56.408  1.00 30.71  ? 270 THR F CA  1 
ATOM   13483 C  C   . THR F 1 270 ? 40.538  9.240   57.073  1.00 29.78  ? 270 THR F C   1 
ATOM   13484 O  O   . THR F 1 270 ? 41.316  8.312   56.821  1.00 21.42  ? 270 THR F O   1 
ATOM   13485 C  CB  . THR F 1 270 ? 39.083  10.368  55.278  1.00 31.60  ? 270 THR F CB  1 
ATOM   13486 O  OG1 . THR F 1 270 ? 37.748  10.726  54.913  1.00 32.03  ? 270 THR F OG1 1 
ATOM   13487 C  CG2 . THR F 1 270 ? 39.815  9.843   54.057  1.00 31.77  ? 270 THR F CG2 1 
ATOM   13488 N  N   . GLU F 1 271 ? 40.836  10.175  57.990  1.00 33.53  ? 271 GLU F N   1 
ATOM   13489 C  CA  . GLU F 1 271 ? 42.125  10.263  58.683  1.00 30.23  ? 271 GLU F CA  1 
ATOM   13490 C  C   . GLU F 1 271 ? 42.365  9.066   59.603  1.00 26.70  ? 271 GLU F C   1 
ATOM   13491 O  O   . GLU F 1 271 ? 43.494  8.603   59.776  1.00 24.76  ? 271 GLU F O   1 
ATOM   13492 C  CB  . GLU F 1 271 ? 42.241  11.587  59.450  1.00 32.19  ? 271 GLU F CB  1 
ATOM   13493 C  CG  . GLU F 1 271 ? 42.645  12.751  58.548  1.00 32.33  ? 271 GLU F CG  1 
ATOM   13494 C  CD  . GLU F 1 271 ? 42.550  14.154  59.106  1.00 34.57  ? 271 GLU F CD  1 
ATOM   13495 O  OE1 . GLU F 1 271 ? 41.925  14.316  60.202  1.00 31.85  ? 271 GLU F OE1 1 
ATOM   13496 O  OE2 . GLU F 1 271 ? 43.091  15.057  58.367  1.00 32.49  ? 271 GLU F OE2 1 
ATOM   13497 N  N   . THR F 1 272 ? 41.295  8.541   60.202  1.00 29.52  ? 272 THR F N   1 
ATOM   13498 C  CA  . THR F 1 272 ? 41.436  7.344   61.017  1.00 28.69  ? 272 THR F CA  1 
ATOM   13499 C  C   . THR F 1 272 ? 41.897  6.183   60.150  1.00 30.09  ? 272 THR F C   1 
ATOM   13500 O  O   . THR F 1 272 ? 42.865  5.497   60.500  1.00 28.16  ? 272 THR F O   1 
ATOM   13501 C  CB  . THR F 1 272 ? 40.109  7.011   61.664  1.00 28.88  ? 272 THR F CB  1 
ATOM   13502 O  OG1 . THR F 1 272 ? 39.965  8.074   62.583  1.00 27.26  ? 272 THR F OG1 1 
ATOM   13503 C  CG2 . THR F 1 272 ? 40.106  5.669   62.365  1.00 28.87  ? 272 THR F CG2 1 
ATOM   13504 N  N   . MET F 1 273 ? 41.206  5.990   59.016  1.00 32.05  ? 273 MET F N   1 
ATOM   13505 C  CA  . MET F 1 273 ? 41.536  4.875   58.136  1.00 32.05  ? 273 MET F CA  1 
ATOM   13506 C  C   . MET F 1 273 ? 42.987  4.986   57.673  1.00 30.55  ? 273 MET F C   1 
ATOM   13507 O  O   . MET F 1 273 ? 43.698  3.984   57.556  1.00 27.48  ? 273 MET F O   1 
ATOM   13508 C  CB  . MET F 1 273 ? 40.587  4.880   56.938  1.00 36.68  ? 273 MET F CB  1 
ATOM   13509 C  CG  . MET F 1 273 ? 39.133  4.573   57.288  1.00 33.72  ? 273 MET F CG  1 
ATOM   13510 S  SD  . MET F 1 273 ? 38.020  4.866   55.897  1.00 30.08  ? 273 MET F SD  1 
ATOM   13511 C  CE  . MET F 1 273 ? 36.447  4.318   56.554  1.00 29.72  ? 273 MET F CE  1 
ATOM   13512 N  N   . LEU F 1 274 ? 43.422  6.230   57.425  1.00 27.38  ? 274 LEU F N   1 
ATOM   13513 C  CA  . LEU F 1 274 ? 44.777  6.465   56.972  1.00 30.34  ? 274 LEU F CA  1 
ATOM   13514 C  C   . LEU F 1 274 ? 45.788  6.117   58.065  1.00 30.80  ? 274 LEU F C   1 
ATOM   13515 O  O   . LEU F 1 274 ? 46.817  5.527   57.736  1.00 30.14  ? 274 LEU F O   1 
ATOM   13516 C  CB  . LEU F 1 274 ? 44.925  7.919   56.529  1.00 34.23  ? 274 LEU F CB  1 
ATOM   13517 C  CG  . LEU F 1 274 ? 44.398  8.259   55.130  1.00 38.20  ? 274 LEU F CG  1 
ATOM   13518 C  CD1 . LEU F 1 274 ? 44.295  9.756   54.843  1.00 34.69  ? 274 LEU F CD1 1 
ATOM   13519 C  CD2 . LEU F 1 274 ? 45.285  7.589   54.080  1.00 40.02  ? 274 LEU F CD2 1 
ATOM   13520 N  N   . GLU F 1 275 ? 45.518  6.500   59.340  1.00 30.75  ? 275 GLU F N   1 
ATOM   13521 C  CA  . GLU F 1 275 ? 46.412  6.161   60.452  1.00 29.42  ? 275 GLU F CA  1 
ATOM   13522 C  C   . GLU F 1 275 ? 46.551  4.642   60.577  1.00 30.37  ? 275 GLU F C   1 
ATOM   13523 O  O   . GLU F 1 275 ? 47.659  4.117   60.625  1.00 37.64  ? 275 GLU F O   1 
ATOM   13524 C  CB  . GLU F 1 275 ? 45.973  6.623   61.837  1.00 32.01  ? 275 GLU F CB  1 
ATOM   13525 C  CG  . GLU F 1 275 ? 46.001  8.132   62.051  1.00 39.21  ? 275 GLU F CG  1 
ATOM   13526 C  CD  . GLU F 1 275 ? 45.364  8.643   63.334  1.00 43.66  ? 275 GLU F CD  1 
ATOM   13527 O  OE1 . GLU F 1 275 ? 45.088  7.886   64.284  1.00 55.88  ? 275 GLU F OE1 1 
ATOM   13528 O  OE2 . GLU F 1 275 ? 45.084  9.842   63.359  1.00 48.44  ? 275 GLU F OE2 1 
ATOM   13529 N  N   . ARG F 1 276 ? 45.423  3.929   60.591  1.00 33.14  ? 276 ARG F N   1 
ATOM   13530 C  CA  . ARG F 1 276 ? 45.411  2.471   60.590  1.00 34.08  ? 276 ARG F CA  1 
ATOM   13531 C  C   . ARG F 1 276 ? 46.287  1.894   59.485  1.00 34.82  ? 276 ARG F C   1 
ATOM   13532 O  O   . ARG F 1 276 ? 47.039  0.967   59.744  1.00 36.61  ? 276 ARG F O   1 
ATOM   13533 C  CB  . ARG F 1 276 ? 43.971  1.957   60.522  1.00 38.01  ? 276 ARG F CB  1 
ATOM   13534 C  CG  . ARG F 1 276 ? 43.443  2.167   61.937  1.00 47.06  ? 276 ARG F CG  1 
ATOM   13535 C  CD  . ARG F 1 276 ? 41.952  2.260   62.075  1.00 56.19  ? 276 ARG F CD  1 
ATOM   13536 N  NE  . ARG F 1 276 ? 41.317  1.003   61.662  1.00 68.06  ? 276 ARG F NE  1 
ATOM   13537 C  CZ  . ARG F 1 276 ? 41.261  -0.110  62.379  1.00 63.58  ? 276 ARG F CZ  1 
ATOM   13538 N  NH1 . ARG F 1 276 ? 41.707  -0.102  63.619  1.00 76.64  ? 276 ARG F NH1 1 
ATOM   13539 N  NH2 . ARG F 1 276 ? 40.720  -1.211  61.877  1.00 53.91  ? 276 ARG F NH2 1 
ATOM   13540 N  N   . MET F 1 277 ? 46.214  2.450   58.270  1.00 34.06  ? 277 MET F N   1 
ATOM   13541 C  CA  . MET F 1 277 ? 46.938  1.910   57.129  1.00 30.59  ? 277 MET F CA  1 
ATOM   13542 C  C   . MET F 1 277 ? 48.435  2.145   57.274  1.00 30.44  ? 277 MET F C   1 
ATOM   13543 O  O   . MET F 1 277 ? 49.223  1.253   57.010  1.00 27.60  ? 277 MET F O   1 
ATOM   13544 C  CB  . MET F 1 277 ? 46.453  2.557   55.821  1.00 32.86  ? 277 MET F CB  1 
ATOM   13545 C  CG  . MET F 1 277 ? 45.106  2.027   55.325  1.00 34.67  ? 277 MET F CG  1 
ATOM   13546 S  SD  . MET F 1 277 ? 44.438  2.959   53.939  1.00 31.87  ? 277 MET F SD  1 
ATOM   13547 C  CE  . MET F 1 277 ? 45.722  2.623   52.713  1.00 35.31  ? 277 MET F CE  1 
ATOM   13548 N  N   . PHE F 1 278 ? 48.820  3.376   57.626  1.00 35.86  ? 278 PHE F N   1 
ATOM   13549 C  CA  . PHE F 1 278 ? 50.220  3.801   57.574  1.00 38.06  ? 278 PHE F CA  1 
ATOM   13550 C  C   . PHE F 1 278 ? 50.944  3.493   58.893  1.00 35.12  ? 278 PHE F C   1 
ATOM   13551 O  O   . PHE F 1 278 ? 52.119  3.186   58.897  1.00 30.27  ? 278 PHE F O   1 
ATOM   13552 C  CB  . PHE F 1 278 ? 50.310  5.295   57.203  1.00 39.98  ? 278 PHE F CB  1 
ATOM   13553 C  CG  . PHE F 1 278 ? 50.200  5.523   55.701  1.00 37.01  ? 278 PHE F CG  1 
ATOM   13554 C  CD1 . PHE F 1 278 ? 48.971  5.536   55.066  1.00 34.43  ? 278 PHE F CD1 1 
ATOM   13555 C  CD2 . PHE F 1 278 ? 51.326  5.649   54.911  1.00 38.43  ? 278 PHE F CD2 1 
ATOM   13556 C  CE1 . PHE F 1 278 ? 48.869  5.658   53.694  1.00 33.16  ? 278 PHE F CE1 1 
ATOM   13557 C  CE2 . PHE F 1 278 ? 51.209  5.766   53.530  1.00 37.35  ? 278 PHE F CE2 1 
ATOM   13558 C  CZ  . PHE F 1 278 ? 49.983  5.762   52.926  1.00 33.02  ? 278 PHE F CZ  1 
ATOM   13559 N  N   . LEU F 1 279 ? 50.253  3.628   60.019  1.00 35.45  ? 279 LEU F N   1 
ATOM   13560 C  CA  . LEU F 1 279 ? 50.894  3.496   61.308  1.00 39.52  ? 279 LEU F CA  1 
ATOM   13561 C  C   . LEU F 1 279 ? 50.615  2.143   61.956  1.00 41.13  ? 279 LEU F C   1 
ATOM   13562 O  O   . LEU F 1 279 ? 51.405  1.700   62.787  1.00 45.43  ? 279 LEU F O   1 
ATOM   13563 C  CB  . LEU F 1 279 ? 50.406  4.657   62.157  1.00 39.81  ? 279 LEU F CB  1 
ATOM   13564 C  CG  . LEU F 1 279 ? 50.703  6.035   61.559  1.00 42.02  ? 279 LEU F CG  1 
ATOM   13565 C  CD1 . LEU F 1 279 ? 50.158  7.080   62.503  1.00 37.94  ? 279 LEU F CD1 1 
ATOM   13566 C  CD2 . LEU F 1 279 ? 52.189  6.247   61.302  1.00 42.20  ? 279 LEU F CD2 1 
ATOM   13567 N  N   . GLY F 1 280 ? 49.531  1.471   61.575  1.00 37.91  ? 280 GLY F N   1 
ATOM   13568 C  CA  . GLY F 1 280 ? 49.324  0.109   62.034  1.00 38.52  ? 280 GLY F CA  1 
ATOM   13569 C  C   . GLY F 1 280 ? 48.402  0.100   63.235  1.00 42.49  ? 280 GLY F C   1 
ATOM   13570 O  O   . GLY F 1 280 ? 47.926  1.166   63.605  1.00 42.44  ? 280 GLY F O   1 
ATOM   13571 N  N   . THR F 1 281 ? 48.142  -1.092  63.793  1.00 44.47  ? 281 THR F N   1 
ATOM   13572 C  CA  . THR F 1 281 ? 47.281  -1.252  64.964  1.00 51.49  ? 281 THR F CA  1 
ATOM   13573 C  C   . THR F 1 281 ? 47.994  -2.160  65.945  1.00 50.93  ? 281 THR F C   1 
ATOM   13574 O  O   . THR F 1 281 ? 49.141  -2.497  65.709  1.00 53.18  ? 281 THR F O   1 
ATOM   13575 C  CB  . THR F 1 281 ? 45.924  -1.879  64.631  1.00 50.52  ? 281 THR F CB  1 
ATOM   13576 O  OG1 . THR F 1 281 ? 46.244  -3.196  64.146  1.00 45.05  ? 281 THR F OG1 1 
ATOM   13577 C  CG2 . THR F 1 281 ? 45.113  -0.945  63.751  1.00 46.83  ? 281 THR F CG2 1 
ATOM   13578 N  N   . ALA F 1 282 ? 47.272  -2.555  67.002  1.00 50.73  ? 282 ALA F N   1 
ATOM   13579 C  CA  . ALA F 1 282 ? 47.639  -3.652  67.878  1.00 46.47  ? 282 ALA F CA  1 
ATOM   13580 C  C   . ALA F 1 282 ? 48.104  -4.875  67.072  1.00 49.72  ? 282 ALA F C   1 
ATOM   13581 O  O   . ALA F 1 282 ? 49.210  -5.340  67.287  1.00 49.60  ? 282 ALA F O   1 
ATOM   13582 C  CB  . ALA F 1 282 ? 46.452  -3.967  68.773  1.00 41.94  ? 282 ALA F CB  1 
ATOM   13583 N  N   . SER F 1 283 ? 47.326  -5.378  66.102  1.00 51.02  ? 283 SER F N   1 
ATOM   13584 C  CA  . SER F 1 283 ? 47.632  -6.681  65.506  1.00 59.00  ? 283 SER F CA  1 
ATOM   13585 C  C   . SER F 1 283 ? 48.210  -6.612  64.081  1.00 60.01  ? 283 SER F C   1 
ATOM   13586 O  O   . SER F 1 283 ? 48.417  -7.663  63.454  1.00 48.48  ? 283 SER F O   1 
ATOM   13587 C  CB  . SER F 1 283 ? 46.416  -7.578  65.525  1.00 58.57  ? 283 SER F CB  1 
ATOM   13588 O  OG  . SER F 1 283 ? 45.302  -6.859  65.016  1.00 57.81  ? 283 SER F OG  1 
ATOM   13589 N  N   . ALA F 1 284 ? 48.511  -5.402  63.581  1.00 58.44  ? 284 ALA F N   1 
ATOM   13590 C  CA  . ALA F 1 284 ? 48.964  -5.248  62.207  1.00 54.29  ? 284 ALA F CA  1 
ATOM   13591 C  C   . ALA F 1 284 ? 50.006  -4.142  62.096  1.00 43.37  ? 284 ALA F C   1 
ATOM   13592 O  O   . ALA F 1 284 ? 49.757  -3.021  62.538  1.00 39.69  ? 284 ALA F O   1 
ATOM   13593 C  CB  . ALA F 1 284 ? 47.760  -4.948  61.351  1.00 62.66  ? 284 ALA F CB  1 
ATOM   13594 N  N   . PRO F 1 285 ? 51.184  -4.415  61.485  1.00 40.69  ? 285 PRO F N   1 
ATOM   13595 C  CA  . PRO F 1 285 ? 52.214  -3.378  61.315  1.00 42.34  ? 285 PRO F CA  1 
ATOM   13596 C  C   . PRO F 1 285 ? 51.736  -2.208  60.442  1.00 48.60  ? 285 PRO F C   1 
ATOM   13597 O  O   . PRO F 1 285 ? 51.974  -1.056  60.767  1.00 48.61  ? 285 PRO F O   1 
ATOM   13598 C  CB  . PRO F 1 285 ? 53.449  -4.122  60.737  1.00 38.75  ? 285 PRO F CB  1 
ATOM   13599 C  CG  . PRO F 1 285 ? 52.896  -5.419  60.202  1.00 41.93  ? 285 PRO F CG  1 
ATOM   13600 C  CD  . PRO F 1 285 ? 51.568  -5.721  60.914  1.00 40.38  ? 285 PRO F CD  1 
ATOM   13601 N  N   . HIS F 1 286 ? 51.055  -2.502  59.327  1.00 53.88  ? 286 HIS F N   1 
ATOM   13602 C  CA  . HIS F 1 286 ? 50.530  -1.504  58.400  1.00 43.55  ? 286 HIS F CA  1 
ATOM   13603 C  C   . HIS F 1 286 ? 49.704  -2.272  57.365  1.00 40.57  ? 286 HIS F C   1 
ATOM   13604 O  O   . HIS F 1 286 ? 49.683  -3.507  57.404  1.00 36.33  ? 286 HIS F O   1 
ATOM   13605 C  CB  . HIS F 1 286 ? 51.650  -0.722  57.709  1.00 37.90  ? 286 HIS F CB  1 
ATOM   13606 C  CG  . HIS F 1 286 ? 52.641  -1.619  57.024  1.00 40.53  ? 286 HIS F CG  1 
ATOM   13607 N  ND1 . HIS F 1 286 ? 53.879  -1.907  57.558  1.00 35.84  ? 286 HIS F ND1 1 
ATOM   13608 C  CD2 . HIS F 1 286 ? 52.583  -2.284  55.854  1.00 38.20  ? 286 HIS F CD2 1 
ATOM   13609 C  CE1 . HIS F 1 286 ? 54.529  -2.703  56.721  1.00 38.22  ? 286 HIS F CE1 1 
ATOM   13610 N  NE2 . HIS F 1 286 ? 53.772  -2.945  55.670  1.00 40.27  ? 286 HIS F NE2 1 
ATOM   13611 N  N   . ASP F 1 287 ? 49.012  -1.536  56.479  1.00 35.01  ? 287 ASP F N   1 
ATOM   13612 C  CA  . ASP F 1 287 ? 48.199  -2.121  55.418  1.00 30.95  ? 287 ASP F CA  1 
ATOM   13613 C  C   . ASP F 1 287 ? 49.094  -2.766  54.368  1.00 26.12  ? 287 ASP F C   1 
ATOM   13614 O  O   . ASP F 1 287 ? 49.883  -2.084  53.739  1.00 23.84  ? 287 ASP F O   1 
ATOM   13615 C  CB  . ASP F 1 287 ? 47.333  -1.057  54.753  1.00 31.43  ? 287 ASP F CB  1 
ATOM   13616 C  CG  . ASP F 1 287 ? 46.191  -1.577  53.890  1.00 27.05  ? 287 ASP F CG  1 
ATOM   13617 O  OD1 . ASP F 1 287 ? 46.377  -2.628  53.264  1.00 24.73  ? 287 ASP F OD1 1 
ATOM   13618 O  OD2 . ASP F 1 287 ? 45.134  -0.936  53.875  1.00 27.75  ? 287 ASP F OD2 1 
ATOM   13619 N  N   . ARG F 1 288 ? 48.933  -4.062  54.134  1.00 24.73  ? 288 ARG F N   1 
ATOM   13620 C  CA  . ARG F 1 288 ? 49.773  -4.760  53.168  1.00 30.40  ? 288 ARG F CA  1 
ATOM   13621 C  C   . ARG F 1 288 ? 49.677  -4.164  51.755  1.00 28.46  ? 288 ARG F C   1 
ATOM   13622 O  O   . ARG F 1 288 ? 50.562  -4.338  50.919  1.00 25.56  ? 288 ARG F O   1 
ATOM   13623 C  CB  . ARG F 1 288 ? 49.362  -6.238  53.119  1.00 35.62  ? 288 ARG F CB  1 
ATOM   13624 C  CG  . ARG F 1 288 ? 49.805  -6.956  54.385  1.00 42.54  ? 288 ARG F CG  1 
ATOM   13625 C  CD  . ARG F 1 288 ? 51.277  -7.315  54.371  1.00 43.69  ? 288 ARG F CD  1 
ATOM   13626 N  NE  . ARG F 1 288 ? 51.480  -8.415  53.412  1.00 44.23  ? 288 ARG F NE  1 
ATOM   13627 C  CZ  . ARG F 1 288 ? 52.372  -8.479  52.413  1.00 44.13  ? 288 ARG F CZ  1 
ATOM   13628 N  NH1 . ARG F 1 288 ? 53.200  -7.479  52.118  1.00 40.56  ? 288 ARG F NH1 1 
ATOM   13629 N  NH2 . ARG F 1 288 ? 52.402  -9.569  51.669  1.00 50.04  ? 288 ARG F NH2 1 
ATOM   13630 N  N   . ILE F 1 289 ? 48.581  -3.482  51.463  1.00 27.15  ? 289 ILE F N   1 
ATOM   13631 C  CA  . ILE F 1 289 ? 48.443  -2.905  50.146  1.00 30.04  ? 289 ILE F CA  1 
ATOM   13632 C  C   . ILE F 1 289 ? 49.570  -1.891  49.919  1.00 31.00  ? 289 ILE F C   1 
ATOM   13633 O  O   . ILE F 1 289 ? 49.952  -1.680  48.756  1.00 33.17  ? 289 ILE F O   1 
ATOM   13634 C  CB  . ILE F 1 289 ? 47.055  -2.275  49.945  1.00 35.22  ? 289 ILE F CB  1 
ATOM   13635 C  CG1 . ILE F 1 289 ? 46.615  -2.364  48.449  1.00 33.67  ? 289 ILE F CG1 1 
ATOM   13636 C  CG2 . ILE F 1 289 ? 46.989  -0.837  50.516  1.00 36.12  ? 289 ILE F CG2 1 
ATOM   13637 C  CD1 . ILE F 1 289 ? 45.204  -1.831  48.168  1.00 28.27  ? 289 ILE F CD1 1 
ATOM   13638 N  N   . LEU F 1 290 ? 50.097  -1.271  50.985  1.00 25.41  ? 290 LEU F N   1 
ATOM   13639 C  CA  . LEU F 1 290 ? 51.114  -0.233  50.833  1.00 27.49  ? 290 LEU F CA  1 
ATOM   13640 C  C   . LEU F 1 290 ? 52.475  -0.841  50.475  1.00 31.06  ? 290 LEU F C   1 
ATOM   13641 O  O   . LEU F 1 290 ? 53.399  -0.132  50.052  1.00 29.51  ? 290 LEU F O   1 
ATOM   13642 C  CB  . LEU F 1 290 ? 51.218  0.616   52.094  1.00 26.86  ? 290 LEU F CB  1 
ATOM   13643 C  CG  . LEU F 1 290 ? 49.935  1.368   52.461  1.00 28.93  ? 290 LEU F CG  1 
ATOM   13644 C  CD1 . LEU F 1 290 ? 50.020  2.036   53.831  1.00 31.04  ? 290 LEU F CD1 1 
ATOM   13645 C  CD2 . LEU F 1 290 ? 49.634  2.428   51.420  1.00 27.63  ? 290 LEU F CD2 1 
ATOM   13646 N  N   . ASP F 1 291 ? 52.577  -2.177  50.610  1.00 30.68  ? 291 ASP F N   1 
ATOM   13647 C  CA  . ASP F 1 291 ? 53.757  -2.896  50.155  1.00 30.69  ? 291 ASP F CA  1 
ATOM   13648 C  C   . ASP F 1 291 ? 53.793  -2.943  48.624  1.00 29.58  ? 291 ASP F C   1 
ATOM   13649 O  O   . ASP F 1 291 ? 54.814  -3.299  48.085  1.00 32.20  ? 291 ASP F O   1 
ATOM   13650 C  CB  . ASP F 1 291 ? 53.937  -4.231  50.876  1.00 31.03  ? 291 ASP F CB  1 
ATOM   13651 C  CG  . ASP F 1 291 ? 54.245  -4.127  52.382  1.00 38.06  ? 291 ASP F CG  1 
ATOM   13652 O  OD1 . ASP F 1 291 ? 54.892  -3.139  52.843  1.00 41.73  ? 291 ASP F OD1 1 
ATOM   13653 O  OD2 . ASP F 1 291 ? 53.827  -5.015  53.142  1.00 37.67  ? 291 ASP F OD2 1 
ATOM   13654 N  N   . PHE F 1 292 ? 52.712  -2.573  47.918  1.00 25.78  ? 292 PHE F N   1 
ATOM   13655 C  CA  . PHE F 1 292 ? 52.716  -2.509  46.461  1.00 25.45  ? 292 PHE F CA  1 
ATOM   13656 C  C   . PHE F 1 292 ? 52.201  -1.169  45.922  1.00 26.02  ? 292 PHE F C   1 
ATOM   13657 O  O   . PHE F 1 292 ? 51.974  -1.030  44.725  1.00 24.16  ? 292 PHE F O   1 
ATOM   13658 C  CB  . PHE F 1 292 ? 51.846  -3.635  45.943  1.00 24.05  ? 292 PHE F CB  1 
ATOM   13659 C  CG  . PHE F 1 292 ? 52.275  -4.959  46.529  1.00 24.60  ? 292 PHE F CG  1 
ATOM   13660 C  CD1 . PHE F 1 292 ? 53.230  -5.744  45.879  1.00 26.45  ? 292 PHE F CD1 1 
ATOM   13661 C  CD2 . PHE F 1 292 ? 51.721  -5.408  47.720  1.00 27.27  ? 292 PHE F CD2 1 
ATOM   13662 C  CE1 . PHE F 1 292 ? 53.615  -6.969  46.413  1.00 25.34  ? 292 PHE F CE1 1 
ATOM   13663 C  CE2 . PHE F 1 292 ? 52.134  -6.620  48.267  1.00 26.74  ? 292 PHE F CE2 1 
ATOM   13664 C  CZ  . PHE F 1 292 ? 53.082  -7.392  47.612  1.00 24.77  ? 292 PHE F CZ  1 
ATOM   13665 N  N   . SER F 1 293 ? 52.109  -0.152  46.786  1.00 25.67  ? 293 SER F N   1 
ATOM   13666 C  CA  . SER F 1 293 ? 51.496  1.113   46.424  1.00 29.17  ? 293 SER F CA  1 
ATOM   13667 C  C   . SER F 1 293 ? 52.220  2.260   47.132  1.00 29.91  ? 293 SER F C   1 
ATOM   13668 O  O   . SER F 1 293 ? 52.271  2.238   48.351  1.00 36.60  ? 293 SER F O   1 
ATOM   13669 C  CB  . SER F 1 293 ? 50.007  1.073   46.789  1.00 27.94  ? 293 SER F CB  1 
ATOM   13670 O  OG  . SER F 1 293 ? 49.428  -0.170  46.388  1.00 24.08  ? 293 SER F OG  1 
ATOM   13671 N  N   . THR F 1 294 ? 52.722  3.254   46.380  1.00 26.10  ? 294 THR F N   1 
ATOM   13672 C  CA  . THR F 1 294 ? 53.371  4.413   46.954  1.00 26.29  ? 294 THR F CA  1 
ATOM   13673 C  C   . THR F 1 294 ? 52.519  5.632   46.657  1.00 26.62  ? 294 THR F C   1 
ATOM   13674 O  O   . THR F 1 294 ? 52.252  5.880   45.483  1.00 26.52  ? 294 THR F O   1 
ATOM   13675 C  CB  . THR F 1 294 ? 54.760  4.627   46.351  1.00 28.27  ? 294 THR F CB  1 
ATOM   13676 O  OG1 . THR F 1 294 ? 55.450  3.482   46.800  1.00 29.03  ? 294 THR F OG1 1 
ATOM   13677 C  CG2 . THR F 1 294 ? 55.504  5.860   46.852  1.00 27.56  ? 294 THR F CG2 1 
ATOM   13678 N  N   . ALA F 1 295 ? 52.174  6.381   47.721  1.00 24.03  ? 295 ALA F N   1 
ATOM   13679 C  CA  . ALA F 1 295 ? 51.456  7.628   47.614  1.00 24.14  ? 295 ALA F CA  1 
ATOM   13680 C  C   . ALA F 1 295 ? 52.466  8.683   47.250  1.00 27.66  ? 295 ALA F C   1 
ATOM   13681 O  O   . ALA F 1 295 ? 53.446  8.798   47.936  1.00 31.98  ? 295 ALA F O   1 
ATOM   13682 C  CB  . ALA F 1 295 ? 50.840  8.017   48.930  1.00 26.10  ? 295 ALA F CB  1 
ATOM   13683 N  N   . VAL F 1 296 ? 52.203  9.477   46.223  1.00 31.19  ? 296 VAL F N   1 
ATOM   13684 C  CA  . VAL F 1 296 ? 53.083  10.560  45.832  1.00 28.63  ? 296 VAL F CA  1 
ATOM   13685 C  C   . VAL F 1 296 ? 52.401  11.922  45.945  1.00 27.58  ? 296 VAL F C   1 
ATOM   13686 O  O   . VAL F 1 296 ? 53.075  12.900  45.695  1.00 30.61  ? 296 VAL F O   1 
ATOM   13687 C  CB  . VAL F 1 296 ? 53.595  10.275  44.412  1.00 27.26  ? 296 VAL F CB  1 
ATOM   13688 C  CG1 . VAL F 1 296 ? 54.031  8.825   44.288  1.00 28.46  ? 296 VAL F CG1 1 
ATOM   13689 C  CG2 . VAL F 1 296 ? 52.592  10.580  43.332  1.00 28.80  ? 296 VAL F CG2 1 
ATOM   13690 N  N   . THR F 1 297 ? 51.098  11.982  46.274  1.00 24.92  ? 297 THR F N   1 
ATOM   13691 C  CA  . THR F 1 297 ? 50.440  13.234  46.601  1.00 26.45  ? 297 THR F CA  1 
ATOM   13692 C  C   . THR F 1 297 ? 49.538  12.972  47.794  1.00 25.67  ? 297 THR F C   1 
ATOM   13693 O  O   . THR F 1 297 ? 49.333  11.810  48.226  1.00 28.69  ? 297 THR F O   1 
ATOM   13694 C  CB  . THR F 1 297 ? 49.617  13.850  45.461  1.00 27.32  ? 297 THR F CB  1 
ATOM   13695 O  OG1 . THR F 1 297 ? 48.467  13.064  45.157  1.00 25.81  ? 297 THR F OG1 1 
ATOM   13696 C  CG2 . THR F 1 297 ? 50.412  14.033  44.181  1.00 29.40  ? 297 THR F CG2 1 
ATOM   13697 N  N   . GLY F 1 298 ? 49.065  14.091  48.348  1.00 22.79  ? 298 GLY F N   1 
ATOM   13698 C  CA  . GLY F 1 298 ? 48.146  14.018  49.472  1.00 21.67  ? 298 GLY F CA  1 
ATOM   13699 C  C   . GLY F 1 298 ? 47.631  15.399  49.796  1.00 20.94  ? 298 GLY F C   1 
ATOM   13700 O  O   . GLY F 1 298 ? 48.423  16.280  50.073  1.00 22.32  ? 298 GLY F O   1 
ATOM   13701 N  N   . SER F 1 299 ? 46.320  15.576  49.727  1.00 21.77  ? 299 SER F N   1 
ATOM   13702 C  CA  . SER F 1 299 ? 45.721  16.860  50.028  1.00 22.95  ? 299 SER F CA  1 
ATOM   13703 C  C   . SER F 1 299 ? 44.310  16.592  50.517  1.00 23.75  ? 299 SER F C   1 
ATOM   13704 O  O   . SER F 1 299 ? 43.689  15.581  50.177  1.00 21.54  ? 299 SER F O   1 
ATOM   13705 C  CB  . SER F 1 299 ? 45.620  17.827  48.843  1.00 25.30  ? 299 SER F CB  1 
ATOM   13706 O  OG  . SER F 1 299 ? 46.717  17.868  47.957  1.00 28.60  ? 299 SER F OG  1 
ATOM   13707 N  N   . LEU F 1 300 ? 43.799  17.582  51.243  1.00 25.26  ? 300 LEU F N   1 
ATOM   13708 C  CA  . LEU F 1 300 ? 42.448  17.581  51.762  1.00 25.96  ? 300 LEU F CA  1 
ATOM   13709 C  C   . LEU F 1 300 ? 41.759  18.862  51.298  1.00 24.64  ? 300 LEU F C   1 
ATOM   13710 O  O   . LEU F 1 300 ? 42.355  19.939  51.238  1.00 26.27  ? 300 LEU F O   1 
ATOM   13711 C  CB  . LEU F 1 300 ? 42.613  17.443  53.278  1.00 30.08  ? 300 LEU F CB  1 
ATOM   13712 C  CG  . LEU F 1 300 ? 41.352  17.349  54.147  1.00 33.59  ? 300 LEU F CG  1 
ATOM   13713 C  CD1 . LEU F 1 300 ? 41.805  17.148  55.597  1.00 38.75  ? 300 LEU F CD1 1 
ATOM   13714 C  CD2 . LEU F 1 300 ? 40.440  18.544  54.117  1.00 36.98  ? 300 LEU F CD2 1 
ATOM   13715 N  N   . PHE F 1 301 ? 40.478  18.739  50.942  1.00 25.99  ? 301 PHE F N   1 
ATOM   13716 C  CA  . PHE F 1 301 ? 39.702  19.875  50.477  1.00 23.08  ? 301 PHE F CA  1 
ATOM   13717 C  C   . PHE F 1 301 ? 38.302  19.804  51.064  1.00 21.53  ? 301 PHE F C   1 
ATOM   13718 O  O   . PHE F 1 301 ? 37.796  18.727  51.389  1.00 20.60  ? 301 PHE F O   1 
ATOM   13719 C  CB  . PHE F 1 301 ? 39.546  19.821  48.963  1.00 24.05  ? 301 PHE F CB  1 
ATOM   13720 C  CG  . PHE F 1 301 ? 40.851  19.767  48.191  1.00 23.09  ? 301 PHE F CG  1 
ATOM   13721 C  CD1 . PHE F 1 301 ? 41.463  20.931  47.761  1.00 23.72  ? 301 PHE F CD1 1 
ATOM   13722 C  CD2 . PHE F 1 301 ? 41.435  18.556  47.866  1.00 22.50  ? 301 PHE F CD2 1 
ATOM   13723 C  CE1 . PHE F 1 301 ? 42.645  20.877  47.042  1.00 23.93  ? 301 PHE F CE1 1 
ATOM   13724 C  CE2 . PHE F 1 301 ? 42.608  18.509  47.144  1.00 23.56  ? 301 PHE F CE2 1 
ATOM   13725 C  CZ  . PHE F 1 301 ? 43.213  19.660  46.738  1.00 23.49  ? 301 PHE F CZ  1 
ATOM   13726 N  N   . PHE F 1 302 ? 37.690  20.975  51.146  1.00 20.29  ? 302 PHE F N   1 
ATOM   13727 C  CA  . PHE F 1 302 ? 36.282  21.124  51.446  1.00 22.09  ? 302 PHE F CA  1 
ATOM   13728 C  C   . PHE F 1 302 ? 35.538  21.459  50.149  1.00 21.85  ? 302 PHE F C   1 
ATOM   13729 O  O   . PHE F 1 302 ? 35.906  22.408  49.450  1.00 18.19  ? 302 PHE F O   1 
ATOM   13730 C  CB  . PHE F 1 302 ? 36.069  22.217  52.508  1.00 22.16  ? 302 PHE F CB  1 
ATOM   13731 C  CG  . PHE F 1 302 ? 34.605  22.341  52.919  1.00 22.83  ? 302 PHE F CG  1 
ATOM   13732 C  CD1 . PHE F 1 302 ? 33.981  21.340  53.675  1.00 22.68  ? 302 PHE F CD1 1 
ATOM   13733 C  CD2 . PHE F 1 302 ? 33.837  23.435  52.513  1.00 23.52  ? 302 PHE F CD2 1 
ATOM   13734 C  CE1 . PHE F 1 302 ? 32.645  21.429  54.005  1.00 21.39  ? 302 PHE F CE1 1 
ATOM   13735 C  CE2 . PHE F 1 302 ? 32.494  23.515  52.862  1.00 24.01  ? 302 PHE F CE2 1 
ATOM   13736 C  CZ  . PHE F 1 302 ? 31.918  22.526  53.623  1.00 22.97  ? 302 PHE F CZ  1 
ATOM   13737 N  N   . THR F 1 303 ? 34.483  20.681  49.865  1.00 22.71  ? 303 THR F N   1 
ATOM   13738 C  CA  . THR F 1 303 ? 33.643  20.868  48.700  1.00 22.29  ? 303 THR F CA  1 
ATOM   13739 C  C   . THR F 1 303 ? 32.333  21.469  49.186  1.00 23.68  ? 303 THR F C   1 
ATOM   13740 O  O   . THR F 1 303 ? 31.436  20.765  49.656  1.00 27.50  ? 303 THR F O   1 
ATOM   13741 C  CB  . THR F 1 303 ? 33.415  19.552  47.954  1.00 24.62  ? 303 THR F CB  1 
ATOM   13742 O  OG1 . THR F 1 303 ? 32.870  18.537  48.790  1.00 25.42  ? 303 THR F OG1 1 
ATOM   13743 C  CG2 . THR F 1 303 ? 34.682  18.934  47.405  1.00 25.75  ? 303 THR F CG2 1 
ATOM   13744 N  N   . PRO F 1 304 ? 32.166  22.801  49.051  1.00 24.86  ? 304 PRO F N   1 
ATOM   13745 C  CA  . PRO F 1 304 ? 30.972  23.488  49.511  1.00 26.18  ? 304 PRO F CA  1 
ATOM   13746 C  C   . PRO F 1 304 ? 29.693  23.020  48.834  1.00 27.60  ? 304 PRO F C   1 
ATOM   13747 O  O   . PRO F 1 304 ? 29.680  22.360  47.805  1.00 30.88  ? 304 PRO F O   1 
ATOM   13748 C  CB  . PRO F 1 304 ? 31.219  24.966  49.217  1.00 25.20  ? 304 PRO F CB  1 
ATOM   13749 C  CG  . PRO F 1 304 ? 32.689  25.075  49.012  1.00 26.16  ? 304 PRO F CG  1 
ATOM   13750 C  CD  . PRO F 1 304 ? 33.112  23.740  48.436  1.00 27.44  ? 304 PRO F CD  1 
ATOM   13751 N  N   . ALA F 1 305 ? 28.601  23.418  49.452  1.00 28.36  ? 305 ALA F N   1 
ATOM   13752 C  CA  . ALA F 1 305 ? 27.318  23.314  48.811  1.00 31.48  ? 305 ALA F CA  1 
ATOM   13753 C  C   . ALA F 1 305 ? 27.375  24.144  47.527  1.00 31.23  ? 305 ALA F C   1 
ATOM   13754 O  O   . ALA F 1 305 ? 28.139  25.101  47.407  1.00 25.77  ? 305 ALA F O   1 
ATOM   13755 C  CB  . ALA F 1 305 ? 26.204  23.714  49.782  1.00 30.08  ? 305 ALA F CB  1 
ATOM   13756 N  N   . ALA F 1 306 ? 26.541  23.731  46.560  1.00 33.99  ? 306 ALA F N   1 
ATOM   13757 C  CA  . ALA F 1 306 ? 26.437  24.436  45.304  1.00 29.64  ? 306 ALA F CA  1 
ATOM   13758 C  C   . ALA F 1 306 ? 26.059  25.897  45.532  1.00 31.60  ? 306 ALA F C   1 
ATOM   13759 O  O   . ALA F 1 306 ? 26.632  26.745  44.853  1.00 31.15  ? 306 ALA F O   1 
ATOM   13760 C  CB  . ALA F 1 306 ? 25.472  23.690  44.420  1.00 27.01  ? 306 ALA F CB  1 
ATOM   13761 N  N   . ASP F 1 307 ? 25.145  26.162  46.499  1.00 38.08  ? 307 ASP F N   1 
ATOM   13762 C  CA  . ASP F 1 307 ? 24.576  27.486  46.728  1.00 45.68  ? 307 ASP F CA  1 
ATOM   13763 C  C   . ASP F 1 307 ? 25.688  28.428  47.170  1.00 49.74  ? 307 ASP F C   1 
ATOM   13764 O  O   . ASP F 1 307 ? 25.723  29.601  46.781  1.00 58.76  ? 307 ASP F O   1 
ATOM   13765 C  CB  . ASP F 1 307 ? 23.562  27.577  47.863  1.00 51.86  ? 307 ASP F CB  1 
ATOM   13766 C  CG  . ASP F 1 307 ? 22.720  26.345  48.121  1.00 66.06  ? 307 ASP F CG  1 
ATOM   13767 O  OD1 . ASP F 1 307 ? 21.820  26.054  47.299  1.00 84.11  ? 307 ASP F OD1 1 
ATOM   13768 O  OD2 . ASP F 1 307 ? 22.991  25.665  49.129  1.00 74.26  ? 307 ASP F OD2 1 
ATOM   13769 N  N   . PHE F 1 308 ? 26.581  27.901  48.015  1.00 42.74  ? 308 PHE F N   1 
ATOM   13770 C  CA  . PHE F 1 308 ? 27.687  28.692  48.510  1.00 37.41  ? 308 PHE F CA  1 
ATOM   13771 C  C   . PHE F 1 308 ? 28.442  29.312  47.331  1.00 37.96  ? 308 PHE F C   1 
ATOM   13772 O  O   . PHE F 1 308 ? 28.697  30.516  47.329  1.00 41.26  ? 308 PHE F O   1 
ATOM   13773 C  CB  . PHE F 1 308 ? 28.551  27.817  49.420  1.00 35.47  ? 308 PHE F CB  1 
ATOM   13774 C  CG  . PHE F 1 308 ? 29.755  28.572  49.953  1.00 36.06  ? 308 PHE F CG  1 
ATOM   13775 C  CD1 . PHE F 1 308 ? 29.663  29.277  51.146  1.00 36.86  ? 308 PHE F CD1 1 
ATOM   13776 C  CD2 . PHE F 1 308 ? 30.973  28.569  49.266  1.00 38.85  ? 308 PHE F CD2 1 
ATOM   13777 C  CE1 . PHE F 1 308 ? 30.761  29.961  51.640  1.00 36.53  ? 308 PHE F CE1 1 
ATOM   13778 C  CE2 . PHE F 1 308 ? 32.072  29.250  49.764  1.00 39.55  ? 308 PHE F CE2 1 
ATOM   13779 C  CZ  . PHE F 1 308 ? 31.955  29.956  50.937  1.00 39.29  ? 308 PHE F CZ  1 
ATOM   13780 N  N   . LEU F 1 309 ? 28.798  28.503  46.322  1.00 35.82  ? 309 LEU F N   1 
ATOM   13781 C  CA  . LEU F 1 309 ? 29.632  28.989  45.223  1.00 39.91  ? 309 LEU F CA  1 
ATOM   13782 C  C   . LEU F 1 309 ? 28.896  30.005  44.341  1.00 38.16  ? 309 LEU F C   1 
ATOM   13783 O  O   . LEU F 1 309 ? 29.473  31.020  43.973  1.00 37.83  ? 309 LEU F O   1 
ATOM   13784 C  CB  . LEU F 1 309 ? 30.153  27.806  44.404  1.00 41.68  ? 309 LEU F CB  1 
ATOM   13785 C  CG  . LEU F 1 309 ? 31.085  26.833  45.135  1.00 40.74  ? 309 LEU F CG  1 
ATOM   13786 C  CD1 . LEU F 1 309 ? 31.270  25.559  44.346  1.00 41.69  ? 309 LEU F CD1 1 
ATOM   13787 C  CD2 . LEU F 1 309 ? 32.427  27.439  45.425  1.00 39.76  ? 309 LEU F CD2 1 
ATOM   13788 N  N   . GLU F 1 310 ? 27.623  29.718  44.031  1.00 48.79  ? 310 GLU F N   1 
ATOM   13789 C  CA  . GLU F 1 310 ? 26.741  30.564  43.234  1.00 47.15  ? 310 GLU F CA  1 
ATOM   13790 C  C   . GLU F 1 310 ? 26.782  32.004  43.730  1.00 43.51  ? 310 GLU F C   1 
ATOM   13791 O  O   . GLU F 1 310 ? 26.955  32.897  42.929  1.00 45.76  ? 310 GLU F O   1 
ATOM   13792 C  CB  . GLU F 1 310 ? 25.316  30.008  43.222  1.00 47.77  ? 310 GLU F CB  1 
ATOM   13793 C  CG  . GLU F 1 310 ? 24.436  30.645  42.150  1.00 57.23  ? 310 GLU F CG  1 
ATOM   13794 C  CD  . GLU F 1 310 ? 23.666  29.601  41.366  1.00 62.60  ? 310 GLU F CD  1 
ATOM   13795 O  OE1 . GLU F 1 310 ? 22.873  28.847  41.971  1.00 80.05  ? 310 GLU F OE1 1 
ATOM   13796 O  OE2 . GLU F 1 310 ? 23.911  29.518  40.147  1.00 57.81  ? 310 GLU F OE2 1 
ATOM   13797 N  N   . ASP F 1 311 ? 26.693  32.222  45.045  1.00 51.58  ? 311 ASP F N   1 
ATOM   13798 C  CA  . ASP F 1 311 ? 26.564  33.561  45.623  1.00 57.82  ? 311 ASP F CA  1 
ATOM   13799 C  C   . ASP F 1 311 ? 27.928  34.089  46.051  1.00 61.46  ? 311 ASP F C   1 
ATOM   13800 O  O   . ASP F 1 311 ? 28.238  34.017  47.247  1.00 70.30  ? 311 ASP F O   1 
ATOM   13801 C  CB  . ASP F 1 311 ? 25.630  33.584  46.829  1.00 54.48  ? 311 ASP F CB  1 
ATOM   13802 C  CG  . ASP F 1 311 ? 24.341  32.776  46.669  1.00 69.05  ? 311 ASP F CG  1 
ATOM   13803 O  OD1 . ASP F 1 311 ? 23.705  32.867  45.573  1.00 72.47  ? 311 ASP F OD1 1 
ATOM   13804 O  OD2 . ASP F 1 311 ? 23.972  32.037  47.637  1.00 71.95  ? 311 ASP F OD2 1 
ATOM   13805 N  N   . LEU F 1 312 ? 28.706  34.617  45.081  1.00 66.19  ? 312 LEU F N   1 
ATOM   13806 C  CA  . LEU F 1 312 ? 30.001  35.233  45.368  1.00 79.30  ? 312 LEU F CA  1 
ATOM   13807 C  C   . LEU F 1 312 ? 30.116  36.658  44.753  1.00 69.91  ? 312 LEU F C   1 
ATOM   13808 O  O   . LEU F 1 312 ? 29.817  36.828  43.552  1.00 59.12  ? 312 LEU F O   1 
ATOM   13809 C  CB  . LEU F 1 312 ? 31.146  34.288  44.964  1.00 72.92  ? 312 LEU F CB  1 
ATOM   13810 C  CG  . LEU F 1 312 ? 31.384  33.053  45.857  1.00 60.70  ? 312 LEU F CG  1 
ATOM   13811 C  CD1 . LEU F 1 312 ? 32.672  32.382  45.458  1.00 56.19  ? 312 LEU F CD1 1 
ATOM   13812 C  CD2 . LEU F 1 312 ? 31.457  33.292  47.354  1.00 55.93  ? 312 LEU F CD2 1 
HETATM 13813 C  CHA . HEM G 2 .   ? 16.899  30.913  26.688  1.00 27.61  ? 401 HEM A CHA 1 
HETATM 13814 C  CHB . HEM G 2 .   ? 15.695  29.943  22.090  1.00 26.00  ? 401 HEM A CHB 1 
HETATM 13815 C  CHC . HEM G 2 .   ? 11.235  31.853  22.834  1.00 25.10  ? 401 HEM A CHC 1 
HETATM 13816 C  CHD . HEM G 2 .   ? 12.408  32.320  27.533  1.00 28.42  ? 401 HEM A CHD 1 
HETATM 13817 C  C1A . HEM G 2 .   ? 16.946  30.510  25.341  1.00 30.15  ? 401 HEM A C1A 1 
HETATM 13818 C  C2A . HEM G 2 .   ? 18.127  30.038  24.689  1.00 28.89  ? 401 HEM A C2A 1 
HETATM 13819 C  C3A . HEM G 2 .   ? 17.780  29.712  23.403  1.00 24.19  ? 401 HEM A C3A 1 
HETATM 13820 C  C4A . HEM G 2 .   ? 16.419  30.032  23.230  1.00 24.58  ? 401 HEM A C4A 1 
HETATM 13821 C  CMA . HEM G 2 .   ? 18.715  29.186  22.390  1.00 24.03  ? 401 HEM A CMA 1 
HETATM 13822 C  CAA . HEM G 2 .   ? 19.479  29.922  25.367  1.00 29.83  ? 401 HEM A CAA 1 
HETATM 13823 C  CBA . HEM G 2 .   ? 19.715  28.534  25.973  1.00 29.34  ? 401 HEM A CBA 1 
HETATM 13824 C  CGA . HEM G 2 .   ? 18.779  28.183  27.065  1.00 30.67  ? 401 HEM A CGA 1 
HETATM 13825 O  O1A . HEM G 2 .   ? 17.855  27.418  26.712  1.00 26.53  ? 401 HEM A O1A 1 
HETATM 13826 O  O2A . HEM G 2 .   ? 19.010  28.613  28.239  1.00 32.01  ? 401 HEM A O2A 1 
HETATM 13827 C  C1B . HEM G 2 .   ? 14.387  30.407  21.918  1.00 29.55  ? 401 HEM A C1B 1 
HETATM 13828 C  C2B . HEM G 2 .   ? 13.727  30.303  20.687  1.00 31.24  ? 401 HEM A C2B 1 
HETATM 13829 C  C3B . HEM G 2 .   ? 12.459  30.788  20.849  1.00 31.87  ? 401 HEM A C3B 1 
HETATM 13830 C  C4B . HEM G 2 .   ? 12.358  31.252  22.256  1.00 29.46  ? 401 HEM A C4B 1 
HETATM 13831 C  CMB . HEM G 2 .   ? 14.304  29.658  19.440  1.00 32.57  ? 401 HEM A CMB 1 
HETATM 13832 C  CAB . HEM G 2 .   ? 11.561  30.931  19.676  1.00 34.89  ? 401 HEM A CAB 1 
HETATM 13833 C  CBB . HEM G 2 .   ? 10.845  32.026  19.453  1.00 35.98  ? 401 HEM A CBB 1 
HETATM 13834 C  C1C . HEM G 2 .   ? 11.121  32.163  24.165  1.00 26.52  ? 401 HEM A C1C 1 
HETATM 13835 C  C2C . HEM G 2 .   ? 10.035  32.761  24.844  1.00 28.63  ? 401 HEM A C2C 1 
HETATM 13836 C  C3C . HEM G 2 .   ? 10.392  32.909  26.188  1.00 26.33  ? 401 HEM A C3C 1 
HETATM 13837 C  C4C . HEM G 2 .   ? 11.700  32.372  26.318  1.00 27.65  ? 401 HEM A C4C 1 
HETATM 13838 C  CMC . HEM G 2 .   ? 8.739   33.147  24.208  1.00 30.93  ? 401 HEM A CMC 1 
HETATM 13839 C  CAC . HEM G 2 .   ? 9.728   33.405  27.403  1.00 24.17  ? 401 HEM A CAC 1 
HETATM 13840 C  CBC . HEM G 2 .   ? 8.503   33.813  27.477  1.00 25.46  ? 401 HEM A CBC 1 
HETATM 13841 C  C1D . HEM G 2 .   ? 13.726  31.957  27.689  1.00 26.18  ? 401 HEM A C1D 1 
HETATM 13842 C  C2D . HEM G 2 .   ? 14.378  31.996  28.970  1.00 27.95  ? 401 HEM A C2D 1 
HETATM 13843 C  C3D . HEM G 2 .   ? 15.665  31.648  28.767  1.00 30.83  ? 401 HEM A C3D 1 
HETATM 13844 C  C4D . HEM G 2 .   ? 15.728  31.382  27.303  1.00 30.19  ? 401 HEM A C4D 1 
HETATM 13845 C  CMD . HEM G 2 .   ? 13.735  32.352  30.275  1.00 28.97  ? 401 HEM A CMD 1 
HETATM 13846 C  CAD . HEM G 2 .   ? 16.804  31.472  29.792  1.00 30.14  ? 401 HEM A CAD 1 
HETATM 13847 C  CBD . HEM G 2 .   ? 17.486  32.818  30.270  1.00 32.73  ? 401 HEM A CBD 1 
HETATM 13848 C  CGD . HEM G 2 .   ? 18.665  32.667  31.279  1.00 29.51  ? 401 HEM A CGD 1 
HETATM 13849 O  O1D . HEM G 2 .   ? 18.677  32.839  32.546  1.00 34.36  ? 401 HEM A O1D 1 
HETATM 13850 O  O2D . HEM G 2 .   ? 19.745  32.323  30.762  1.00 27.47  ? 401 HEM A O2D 1 
HETATM 13851 N  NA  . HEM G 2 .   ? 15.904  30.526  24.387  1.00 28.25  ? 401 HEM A NA  1 
HETATM 13852 N  NB  . HEM G 2 .   ? 13.564  30.972  22.812  1.00 31.37  ? 401 HEM A NB  1 
HETATM 13853 N  NC  . HEM G 2 .   ? 12.095  31.940  25.085  1.00 27.91  ? 401 HEM A NC  1 
HETATM 13854 N  ND  . HEM G 2 .   ? 14.530  31.593  26.698  1.00 28.80  ? 401 HEM A ND  1 
HETATM 13855 FE FE  . HEM G 2 .   ? 14.110  31.385  24.809  1.00 25.37  ? 401 HEM A FE  1 
HETATM 13856 MG MG  . MG  H 3 .   ? 12.306  32.267  2.910   1.00 26.75  ? 402 MG  A MG  1 
HETATM 13857 C  CHA . HEM I 2 .   ? 39.088  -23.919 24.123  1.00 26.10  ? 401 HEM B CHA 1 
HETATM 13858 C  CHB . HEM I 2 .   ? 36.028  -24.684 27.798  1.00 22.53  ? 401 HEM B CHB 1 
HETATM 13859 C  CHC . HEM I 2 .   ? 34.748  -28.952 25.937  1.00 24.91  ? 401 HEM B CHC 1 
HETATM 13860 C  CHD . HEM I 2 .   ? 37.251  -27.784 21.950  1.00 23.76  ? 401 HEM B CHD 1 
HETATM 13861 C  C1A . HEM I 2 .   ? 38.402  -23.843 25.361  1.00 24.40  ? 401 HEM B C1A 1 
HETATM 13862 C  C2A . HEM I 2 .   ? 38.573  -22.757 26.292  1.00 22.07  ? 401 HEM B C2A 1 
HETATM 13863 C  C3A . HEM I 2 .   ? 37.714  -22.968 27.317  1.00 20.69  ? 401 HEM B C3A 1 
HETATM 13864 C  C4A . HEM I 2 .   ? 36.985  -24.148 26.986  1.00 22.24  ? 401 HEM B C4A 1 
HETATM 13865 C  CMA . HEM I 2 .   ? 37.529  -22.090 28.561  1.00 19.64  ? 401 HEM B CMA 1 
HETATM 13866 C  CAA . HEM I 2 .   ? 39.522  -21.596 26.173  1.00 24.41  ? 401 HEM B CAA 1 
HETATM 13867 C  CBA . HEM I 2 .   ? 38.901  -20.308 25.565  1.00 26.86  ? 401 HEM B CBA 1 
HETATM 13868 C  CGA . HEM I 2 .   ? 38.465  -20.554 24.084  1.00 31.18  ? 401 HEM B CGA 1 
HETATM 13869 O  O1A . HEM I 2 .   ? 37.306  -20.959 23.695  1.00 28.80  ? 401 HEM B O1A 1 
HETATM 13870 O  O2A . HEM I 2 .   ? 39.299  -20.342 23.151  1.00 35.98  ? 401 HEM B O2A 1 
HETATM 13871 C  C1B . HEM I 2 .   ? 35.447  -25.895 27.570  1.00 23.40  ? 401 HEM B C1B 1 
HETATM 13872 C  C2B . HEM I 2 .   ? 34.577  -26.438 28.553  1.00 24.92  ? 401 HEM B C2B 1 
HETATM 13873 C  C3B . HEM I 2 .   ? 34.177  -27.644 28.072  1.00 27.19  ? 401 HEM B C3B 1 
HETATM 13874 C  C4B . HEM I 2 .   ? 34.872  -27.847 26.759  1.00 26.34  ? 401 HEM B C4B 1 
HETATM 13875 C  CMB . HEM I 2 .   ? 34.172  -25.845 29.859  1.00 23.50  ? 401 HEM B CMB 1 
HETATM 13876 C  CAB . HEM I 2 .   ? 33.389  -28.540 28.913  1.00 32.93  ? 401 HEM B CAB 1 
HETATM 13877 C  CBB . HEM I 2 .   ? 33.790  -29.797 28.975  1.00 35.73  ? 401 HEM B CBB 1 
HETATM 13878 C  C1C . HEM I 2 .   ? 35.322  -29.018 24.670  1.00 24.33  ? 401 HEM B C1C 1 
HETATM 13879 C  C2C . HEM I 2 .   ? 35.207  -30.100 23.749  1.00 22.55  ? 401 HEM B C2C 1 
HETATM 13880 C  C3C . HEM I 2 .   ? 35.922  -29.789 22.605  1.00 22.83  ? 401 HEM B C3C 1 
HETATM 13881 C  C4C . HEM I 2 .   ? 36.471  -28.495 22.867  1.00 22.08  ? 401 HEM B C4C 1 
HETATM 13882 C  CMC . HEM I 2 .   ? 34.446  -31.340 24.026  1.00 23.13  ? 401 HEM B CMC 1 
HETATM 13883 C  CAC . HEM I 2 .   ? 36.102  -30.515 21.290  1.00 23.69  ? 401 HEM B CAC 1 
HETATM 13884 C  CBC . HEM I 2 .   ? 35.500  -31.610 20.816  1.00 23.87  ? 401 HEM B CBC 1 
HETATM 13885 C  C1D . HEM I 2 .   ? 37.971  -26.605 22.224  1.00 25.76  ? 401 HEM B C1D 1 
HETATM 13886 C  C2D . HEM I 2 .   ? 38.857  -25.965 21.217  1.00 26.06  ? 401 HEM B C2D 1 
HETATM 13887 C  C3D . HEM I 2 .   ? 39.438  -24.881 21.782  1.00 27.81  ? 401 HEM B C3D 1 
HETATM 13888 C  C4D . HEM I 2 .   ? 38.800  -24.889 23.148  1.00 24.02  ? 401 HEM B C4D 1 
HETATM 13889 C  CMD . HEM I 2 .   ? 39.159  -26.457 19.791  1.00 26.33  ? 401 HEM B CMD 1 
HETATM 13890 C  CAD . HEM I 2 .   ? 40.553  -23.922 21.117  1.00 32.55  ? 401 HEM B CAD 1 
HETATM 13891 C  CBD . HEM I 2 .   ? 41.860  -24.383 20.260  1.00 35.99  ? 401 HEM B CBD 1 
HETATM 13892 C  CGD . HEM I 2 .   ? 42.925  -23.266 20.192  1.00 35.07  ? 401 HEM B CGD 1 
HETATM 13893 O  O1D . HEM I 2 .   ? 43.051  -22.710 21.333  1.00 27.88  ? 401 HEM B O1D 1 
HETATM 13894 O  O2D . HEM I 2 .   ? 43.620  -22.853 19.136  1.00 48.81  ? 401 HEM B O2D 1 
HETATM 13895 N  NA  . HEM I 2 .   ? 37.395  -24.698 25.812  1.00 22.15  ? 401 HEM B NA  1 
HETATM 13896 N  NB  . HEM I 2 .   ? 35.642  -26.748 26.548  1.00 24.28  ? 401 HEM B NB  1 
HETATM 13897 N  NC  . HEM I 2 .   ? 36.104  -28.085 24.112  1.00 20.94  ? 401 HEM B NC  1 
HETATM 13898 N  ND  . HEM I 2 .   ? 37.919  -25.920 23.368  1.00 24.26  ? 401 HEM B ND  1 
HETATM 13899 FE FE  . HEM I 2 .   ? 36.862  -26.392 24.910  1.00 24.46  ? 401 HEM B FE  1 
HETATM 13900 C  CHA . HEM J 2 .   ? 2.901   -8.655  3.236   1.00 31.58  ? 401 HEM C CHA 1 
HETATM 13901 C  CHB . HEM J 2 .   ? 0.744   -4.730  5.075   1.00 32.18  ? 401 HEM C CHB 1 
HETATM 13902 C  CHC . HEM J 2 .   ? 0.451   -2.944  0.547   1.00 26.25  ? 401 HEM C CHC 1 
HETATM 13903 C  CHD . HEM J 2 .   ? 3.189   -6.656  -1.092  1.00 30.31  ? 401 HEM C CHD 1 
HETATM 13904 C  C1A . HEM J 2 .   ? 2.293   -7.751  4.117   1.00 30.55  ? 401 HEM C C1A 1 
HETATM 13905 C  C2A . HEM J 2 .   ? 1.993   -8.027  5.499   1.00 27.82  ? 401 HEM C C2A 1 
HETATM 13906 C  C3A . HEM J 2 .   ? 1.408   -6.936  5.989   1.00 28.31  ? 401 HEM C C3A 1 
HETATM 13907 C  C4A . HEM J 2 .   ? 1.364   -5.953  4.968   1.00 31.49  ? 401 HEM C C4A 1 
HETATM 13908 C  CMA . HEM J 2 .   ? 0.872   -6.776  7.361   1.00 28.70  ? 401 HEM C CMA 1 
HETATM 13909 C  CAA . HEM J 2 .   ? 2.248   -9.311  6.254   1.00 29.22  ? 401 HEM C CAA 1 
HETATM 13910 C  CBA . HEM J 2 .   ? 3.668   -9.365  6.890   1.00 28.93  ? 401 HEM C CBA 1 
HETATM 13911 C  CGA . HEM J 2 .   ? 4.796   -9.115  5.949   1.00 26.87  ? 401 HEM C CGA 1 
HETATM 13912 O  O1A . HEM J 2 .   ? 5.336   -10.076 5.382   1.00 28.50  ? 401 HEM C O1A 1 
HETATM 13913 O  O2A . HEM J 2 .   ? 5.177   -7.950  5.726   1.00 25.52  ? 401 HEM C O2A 1 
HETATM 13914 C  C1B . HEM J 2 .   ? 0.455   -3.943  3.944   1.00 32.05  ? 401 HEM C C1B 1 
HETATM 13915 C  C2B . HEM J 2 .   ? -0.258  -2.678  4.047   1.00 33.52  ? 401 HEM C C2B 1 
HETATM 13916 C  C3B . HEM J 2 .   ? -0.277  -2.177  2.750   1.00 31.01  ? 401 HEM C C3B 1 
HETATM 13917 C  C4B . HEM J 2 .   ? 0.354   -3.176  1.894   1.00 28.83  ? 401 HEM C C4B 1 
HETATM 13918 C  CMB . HEM J 2 .   ? -0.765  -2.012  5.337   1.00 29.21  ? 401 HEM C CMB 1 
HETATM 13919 C  CAB . HEM J 2 .   ? -0.934  -1.044  2.128   1.00 32.77  ? 401 HEM C CAB 1 
HETATM 13920 C  CBB . HEM J 2 .   ? -2.075  -0.757  2.649   1.00 36.06  ? 401 HEM C CBB 1 
HETATM 13921 C  C1C . HEM J 2 .   ? 1.156   -3.760  -0.299  1.00 28.03  ? 401 HEM C C1C 1 
HETATM 13922 C  C2C . HEM J 2 .   ? 1.326   -3.514  -1.712  1.00 29.64  ? 401 HEM C C2C 1 
HETATM 13923 C  C3C . HEM J 2 .   ? 2.105   -4.619  -2.194  1.00 25.97  ? 401 HEM C C3C 1 
HETATM 13924 C  C4C . HEM J 2 .   ? 2.386   -5.482  -1.027  1.00 29.48  ? 401 HEM C C4C 1 
HETATM 13925 C  CMC . HEM J 2 .   ? 0.726   -2.266  -2.425  1.00 29.25  ? 401 HEM C CMC 1 
HETATM 13926 C  CAC . HEM J 2 .   ? 2.689   -4.959  -3.502  1.00 22.54  ? 401 HEM C CAC 1 
HETATM 13927 C  CBC . HEM J 2 .   ? 2.556   -4.158  -4.498  1.00 25.49  ? 401 HEM C CBC 1 
HETATM 13928 C  C1D . HEM J 2 .   ? 3.392   -7.512  -0.025  1.00 29.21  ? 401 HEM C C1D 1 
HETATM 13929 C  C2D . HEM J 2 .   ? 4.108   -8.770  -0.155  1.00 28.39  ? 401 HEM C C2D 1 
HETATM 13930 C  C3D . HEM J 2 .   ? 3.994   -9.365  1.043   1.00 30.58  ? 401 HEM C C3D 1 
HETATM 13931 C  C4D . HEM J 2 .   ? 3.184   -8.419  1.879   1.00 30.20  ? 401 HEM C C4D 1 
HETATM 13932 C  CMD . HEM J 2 .   ? 4.814   -9.323  -1.364  1.00 32.30  ? 401 HEM C CMD 1 
HETATM 13933 C  CAD . HEM J 2 .   ? 4.538   -10.732 1.520   1.00 33.47  ? 401 HEM C CAD 1 
HETATM 13934 C  CBD . HEM J 2 .   ? 3.811   -12.020 0.989   1.00 34.85  ? 401 HEM C CBD 1 
HETATM 13935 C  CGD . HEM J 2 .   ? 4.557   -13.342 1.348   1.00 38.03  ? 401 HEM C CGD 1 
HETATM 13936 O  O1D . HEM J 2 .   ? 4.343   -13.750 2.518   1.00 35.08  ? 401 HEM C O1D 1 
HETATM 13937 O  O2D . HEM J 2 .   ? 5.374   -14.023 0.584   1.00 37.31  ? 401 HEM C O2D 1 
HETATM 13938 N  NA  . HEM J 2 .   ? 1.880   -6.471  3.798   1.00 29.90  ? 401 HEM C NA  1 
HETATM 13939 N  NB  . HEM J 2 .   ? 0.794   -4.175  2.654   1.00 29.76  ? 401 HEM C NB  1 
HETATM 13940 N  NC  . HEM J 2 .   ? 1.791   -4.905  0.087   1.00 25.46  ? 401 HEM C NC  1 
HETATM 13941 N  ND  . HEM J 2 .   ? 2.837   -7.305  1.205   1.00 31.02  ? 401 HEM C ND  1 
HETATM 13942 FE FE  . HEM J 2 .   ? 1.774   -5.831  1.899   1.00 28.33  ? 401 HEM C FE  1 
HETATM 13943 C  CHA . HEM K 2 .   ? 40.167  16.524  5.326   1.00 22.71  ? 401 HEM D CHA 1 
HETATM 13944 C  CHB . HEM K 2 .   ? 41.592  18.129  9.691   1.00 26.12  ? 401 HEM D CHB 1 
HETATM 13945 C  CHC . HEM K 2 .   ? 46.121  16.790  8.647   1.00 23.53  ? 401 HEM D CHC 1 
HETATM 13946 C  CHD . HEM K 2 .   ? 44.543  14.818  4.589   1.00 21.06  ? 401 HEM D CHD 1 
HETATM 13947 C  C1A . HEM K 2 .   ? 40.197  17.092  6.627   1.00 23.62  ? 401 HEM D C1A 1 
HETATM 13948 C  C2A . HEM K 2 .   ? 39.059  17.718  7.245   1.00 21.06  ? 401 HEM D C2A 1 
HETATM 13949 C  C3A . HEM K 2 .   ? 39.441  18.149  8.457   1.00 20.30  ? 401 HEM D C3A 1 
HETATM 13950 C  C4A . HEM K 2 .   ? 40.818  17.802  8.615   1.00 24.30  ? 401 HEM D C4A 1 
HETATM 13951 C  CMA . HEM K 2 .   ? 38.638  18.900  9.444   1.00 20.47  ? 401 HEM D CMA 1 
HETATM 13952 C  CAA . HEM K 2 .   ? 37.720  17.892  6.575   1.00 21.47  ? 401 HEM D CAA 1 
HETATM 13953 C  CBA . HEM K 2 .   ? 36.766  16.754  6.850   1.00 21.52  ? 401 HEM D CBA 1 
HETATM 13954 C  CGA . HEM K 2 .   ? 37.216  15.414  6.348   1.00 21.92  ? 401 HEM D CGA 1 
HETATM 13955 O  O1A . HEM K 2 .   ? 36.951  15.018  5.175   1.00 22.88  ? 401 HEM D O1A 1 
HETATM 13956 O  O2A . HEM K 2 .   ? 37.842  14.681  7.181   1.00 26.22  ? 401 HEM D O2A 1 
HETATM 13957 C  C1B . HEM K 2 .   ? 42.973  17.936  9.735   1.00 26.76  ? 401 HEM D C1B 1 
HETATM 13958 C  C2B . HEM K 2 .   ? 43.760  18.259  10.891  1.00 26.31  ? 401 HEM D C2B 1 
HETATM 13959 C  C3B . HEM K 2 .   ? 45.025  17.833  10.567  1.00 27.08  ? 401 HEM D C3B 1 
HETATM 13960 C  C4B . HEM K 2 .   ? 44.995  17.273  9.245   1.00 25.82  ? 401 HEM D C4B 1 
HETATM 13961 C  CMB . HEM K 2 .   ? 43.274  18.886  12.203  1.00 25.89  ? 401 HEM D CMB 1 
HETATM 13962 C  CAB . HEM K 2 .   ? 46.329  17.970  11.160  1.00 30.96  ? 401 HEM D CAB 1 
HETATM 13963 C  CBB . HEM K 2 .   ? 46.539  18.994  11.930  1.00 34.38  ? 401 HEM D CBB 1 
HETATM 13964 C  C1C . HEM K 2 .   ? 46.121  16.145  7.436   1.00 25.15  ? 401 HEM D C1C 1 
HETATM 13965 C  C2C . HEM K 2 .   ? 47.254  15.658  6.783   1.00 25.47  ? 401 HEM D C2C 1 
HETATM 13966 C  C3C . HEM K 2 .   ? 46.811  15.108  5.619   1.00 23.17  ? 401 HEM D C3C 1 
HETATM 13967 C  C4C . HEM K 2 .   ? 45.386  15.253  5.605   1.00 21.65  ? 401 HEM D C4C 1 
HETATM 13968 C  CMC . HEM K 2 .   ? 48.633  15.786  7.365   1.00 27.81  ? 401 HEM D CMC 1 
HETATM 13969 C  CAC . HEM K 2 .   ? 47.513  14.402  4.530   1.00 24.82  ? 401 HEM D CAC 1 
HETATM 13970 C  CBC . HEM K 2 .   ? 48.762  14.030  4.541   1.00 27.33  ? 401 HEM D CBC 1 
HETATM 13971 C  C1D . HEM K 2 .   ? 43.199  15.102  4.480   1.00 20.38  ? 401 HEM D C1D 1 
HETATM 13972 C  C2D . HEM K 2 .   ? 42.422  14.666  3.331   1.00 19.92  ? 401 HEM D C2D 1 
HETATM 13973 C  C3D . HEM K 2 .   ? 41.174  15.197  3.471   1.00 19.43  ? 401 HEM D C3D 1 
HETATM 13974 C  C4D . HEM K 2 .   ? 41.246  15.904  4.754   1.00 19.33  ? 401 HEM D C4D 1 
HETATM 13975 C  CMD . HEM K 2 .   ? 42.954  13.799  2.212   1.00 20.10  ? 401 HEM D CMD 1 
HETATM 13976 C  CAD . HEM K 2 .   ? 40.005  15.022  2.544   1.00 19.26  ? 401 HEM D CAD 1 
HETATM 13977 C  CBD . HEM K 2 .   ? 40.030  15.799  1.191   1.00 21.34  ? 401 HEM D CBD 1 
HETATM 13978 C  CGD . HEM K 2 .   ? 38.753  15.677  0.321   1.00 25.63  ? 401 HEM D CGD 1 
HETATM 13979 O  O1D . HEM K 2 .   ? 37.950  16.440  0.908   1.00 25.27  ? 401 HEM D O1D 1 
HETATM 13980 O  O2D . HEM K 2 .   ? 38.372  14.997  -0.786  1.00 34.09  ? 401 HEM D O2D 1 
HETATM 13981 N  NA  . HEM K 2 .   ? 41.294  17.157  7.514   1.00 22.64  ? 401 HEM D NA  1 
HETATM 13982 N  NB  . HEM K 2 .   ? 43.754  17.381  8.808   1.00 23.79  ? 401 HEM D NB  1 
HETATM 13983 N  NC  . HEM K 2 .   ? 45.033  15.889  6.709   1.00 22.21  ? 401 HEM D NC  1 
HETATM 13984 N  ND  . HEM K 2 .   ? 42.490  15.843  5.343   1.00 21.80  ? 401 HEM D ND  1 
HETATM 13985 FE FE  . HEM K 2 .   ? 43.156  16.660  7.004   1.00 21.43  ? 401 HEM D FE  1 
HETATM 13986 O  O1  . PG4 L 4 .   ? 68.955  -10.855 8.859   1.00 45.18  ? 402 PG4 D O1  1 
HETATM 13987 C  C1  . PG4 L 4 .   ? 67.616  -11.163 9.063   1.00 52.52  ? 402 PG4 D C1  1 
HETATM 13988 C  C2  . PG4 L 4 .   ? 67.385  -11.700 10.447  1.00 67.22  ? 402 PG4 D C2  1 
HETATM 13989 O  O2  . PG4 L 4 .   ? 67.596  -13.110 10.456  1.00 81.36  ? 402 PG4 D O2  1 
HETATM 13990 C  C3  . PG4 L 4 .   ? 66.606  -13.855 11.171  1.00 80.73  ? 402 PG4 D C3  1 
HETATM 13991 C  C4  . PG4 L 4 .   ? 65.276  -14.001 10.383  1.00 87.21  ? 402 PG4 D C4  1 
HETATM 13992 O  O3  . PG4 L 4 .   ? 65.423  -14.095 8.957   1.00 78.39  ? 402 PG4 D O3  1 
HETATM 13993 C  C5  . PG4 L 4 .   ? 64.253  -13.765 8.203   1.00 72.48  ? 402 PG4 D C5  1 
HETATM 13994 C  C6  . PG4 L 4 .   ? 63.433  -14.995 7.865   1.00 70.16  ? 402 PG4 D C6  1 
HETATM 13995 O  O4  . PG4 L 4 .   ? 62.036  -14.684 7.905   1.00 81.74  ? 402 PG4 D O4  1 
HETATM 13996 C  C7  . PG4 L 4 .   ? 61.605  -13.719 6.937   1.00 80.07  ? 402 PG4 D C7  1 
HETATM 13997 C  C8  . PG4 L 4 .   ? 60.088  -13.634 6.872   1.00 74.27  ? 402 PG4 D C8  1 
HETATM 13998 O  O5  . PG4 L 4 .   ? 59.423  -14.375 7.915   1.00 66.08  ? 402 PG4 D O5  1 
HETATM 13999 C  CHA . HEM M 2 .   ? -4.033  -7.428  37.213  1.00 25.22  ? 401 HEM E CHA 1 
HETATM 14000 C  CHB . HEM M 2 .   ? -2.468  -11.526 35.223  1.00 29.43  ? 401 HEM E CHB 1 
HETATM 14001 C  CHC . HEM M 2 .   ? -2.860  -13.806 39.407  1.00 27.81  ? 401 HEM E CHC 1 
HETATM 14002 C  CHD . HEM M 2 .   ? -3.809  -9.486  41.503  1.00 22.76  ? 401 HEM E CHD 1 
HETATM 14003 C  C1A . HEM M 2 .   ? -3.626  -8.345  36.298  1.00 25.69  ? 401 HEM E C1A 1 
HETATM 14004 C  C2A . HEM M 2 .   ? -3.562  -8.078  34.888  1.00 23.43  ? 401 HEM E C2A 1 
HETATM 14005 C  C3A . HEM M 2 .   ? -3.147  -9.253  34.345  1.00 25.82  ? 401 HEM E C3A 1 
HETATM 14006 C  C4A . HEM M 2 .   ? -2.951  -10.221 35.381  1.00 27.89  ? 401 HEM E C4A 1 
HETATM 14007 C  CMA . HEM M 2 .   ? -2.885  -9.550  32.871  1.00 28.15  ? 401 HEM E CMA 1 
HETATM 14008 C  CAA . HEM M 2 .   ? -3.955  -6.840  34.137  1.00 23.30  ? 401 HEM E CAA 1 
HETATM 14009 C  CBA . HEM M 2 .   ? -2.776  -5.889  33.928  1.00 25.97  ? 401 HEM E CBA 1 
HETATM 14010 C  CGA . HEM M 2 .   ? -2.166  -5.465  35.231  1.00 26.95  ? 401 HEM E CGA 1 
HETATM 14011 O  O1A . HEM M 2 .   ? -2.720  -4.477  35.852  1.00 28.68  ? 401 HEM E O1A 1 
HETATM 14012 O  O2A . HEM M 2 .   ? -1.142  -6.176  35.620  1.00 23.43  ? 401 HEM E O2A 1 
HETATM 14013 C  C1B . HEM M 2 .   ? -2.404  -12.504 36.185  1.00 27.75  ? 401 HEM E C1B 1 
HETATM 14014 C  C2B . HEM M 2 .   ? -2.017  -13.836 35.882  1.00 26.20  ? 401 HEM E C2B 1 
HETATM 14015 C  C3B . HEM M 2 .   ? -2.114  -14.535 37.043  1.00 30.99  ? 401 HEM E C3B 1 
HETATM 14016 C  C4B . HEM M 2 .   ? -2.628  -13.546 38.068  1.00 31.07  ? 401 HEM E C4B 1 
HETATM 14017 C  CMB . HEM M 2 .   ? -1.570  -14.485 34.600  1.00 26.07  ? 401 HEM E CMB 1 
HETATM 14018 C  CAB . HEM M 2 .   ? -1.937  -16.021 36.997  1.00 34.97  ? 401 HEM E CAB 1 
HETATM 14019 C  CBB . HEM M 2 .   ? -2.650  -16.897 37.695  1.00 33.67  ? 401 HEM E CBB 1 
HETATM 14020 C  C1C . HEM M 2 .   ? -3.163  -12.820 40.377  1.00 26.69  ? 401 HEM E C1C 1 
HETATM 14021 C  C2C . HEM M 2 .   ? -3.399  -13.036 41.777  1.00 25.57  ? 401 HEM E C2C 1 
HETATM 14022 C  C3C . HEM M 2 .   ? -3.673  -11.773 42.341  1.00 25.08  ? 401 HEM E C3C 1 
HETATM 14023 C  C4C . HEM M 2 .   ? -3.597  -10.817 41.304  1.00 22.94  ? 401 HEM E C4C 1 
HETATM 14024 C  CMC . HEM M 2 .   ? -3.340  -14.434 42.422  1.00 27.74  ? 401 HEM E CMC 1 
HETATM 14025 C  CAC . HEM M 2 .   ? -3.915  -11.377 43.731  1.00 26.33  ? 401 HEM E CAC 1 
HETATM 14026 C  CBC . HEM M 2 .   ? -3.659  -12.215 44.692  1.00 27.82  ? 401 HEM E CBC 1 
HETATM 14027 C  C1D . HEM M 2 .   ? -3.936  -8.652  40.428  1.00 22.67  ? 401 HEM E C1D 1 
HETATM 14028 C  C2D . HEM M 2 .   ? -4.254  -7.279  40.665  1.00 23.90  ? 401 HEM E C2D 1 
HETATM 14029 C  C3D . HEM M 2 .   ? -4.384  -6.676  39.469  1.00 23.93  ? 401 HEM E C3D 1 
HETATM 14030 C  C4D . HEM M 2 .   ? -4.036  -7.737  38.543  1.00 23.86  ? 401 HEM E C4D 1 
HETATM 14031 C  CMD . HEM M 2 .   ? -4.514  -6.681  42.017  1.00 27.45  ? 401 HEM E CMD 1 
HETATM 14032 C  CAD . HEM M 2 .   ? -4.764  -5.234  39.146  1.00 26.61  ? 401 HEM E CAD 1 
HETATM 14033 C  CBD . HEM M 2 .   ? -6.250  -4.836  39.413  1.00 27.85  ? 401 HEM E CBD 1 
HETATM 14034 C  CGD . HEM M 2 .   ? -6.502  -3.351  39.071  1.00 31.33  ? 401 HEM E CGD 1 
HETATM 14035 O  O1D . HEM M 2 .   ? -6.721  -2.333  39.865  1.00 34.42  ? 401 HEM E O1D 1 
HETATM 14036 O  O2D . HEM M 2 .   ? -6.495  -3.170  37.843  1.00 26.11  ? 401 HEM E O2D 1 
HETATM 14037 N  NA  . HEM M 2 .   ? -3.254  -9.661  36.571  1.00 27.12  ? 401 HEM E NA  1 
HETATM 14038 N  NB  . HEM M 2 .   ? -2.761  -12.388 37.451  1.00 27.94  ? 401 HEM E NB  1 
HETATM 14039 N  NC  . HEM M 2 .   ? -3.298  -11.493 40.145  1.00 25.19  ? 401 HEM E NC  1 
HETATM 14040 N  ND  . HEM M 2 .   ? -3.820  -8.935  39.133  1.00 23.74  ? 401 HEM E ND  1 
HETATM 14041 FE FE  . HEM M 2 .   ? -3.345  -10.631 38.302  1.00 27.39  ? 401 HEM E FE  1 
HETATM 14042 C  CHA . HEM N 2 .   ? 38.035  -1.275  49.864  1.00 27.93  ? 401 HEM F CHA 1 
HETATM 14043 C  CHB . HEM N 2 .   ? 41.556  -0.877  46.614  1.00 32.52  ? 401 HEM F CHB 1 
HETATM 14044 C  CHC . HEM N 2 .   ? 43.250  3.037   49.031  1.00 24.31  ? 401 HEM F CHC 1 
HETATM 14045 C  CHD . HEM N 2 .   ? 39.457  2.843   51.890  1.00 22.45  ? 401 HEM F CHD 1 
HETATM 14046 C  C1A . HEM N 2 .   ? 38.832  -1.499  48.777  1.00 26.01  ? 401 HEM F C1A 1 
HETATM 14047 C  C2A . HEM N 2 .   ? 38.679  -2.623  47.922  1.00 24.21  ? 401 HEM F C2A 1 
HETATM 14048 C  C3A . HEM N 2 .   ? 39.710  -2.517  47.030  1.00 25.31  ? 401 HEM F C3A 1 
HETATM 14049 C  C4A . HEM N 2 .   ? 40.442  -1.332  47.317  1.00 27.19  ? 401 HEM F C4A 1 
HETATM 14050 C  CMA . HEM N 2 .   ? 40.033  -3.477  45.926  1.00 25.27  ? 401 HEM F CMA 1 
HETATM 14051 C  CAA . HEM N 2 .   ? 37.695  -3.758  48.051  1.00 23.33  ? 401 HEM F CAA 1 
HETATM 14052 C  CBA . HEM N 2 .   ? 36.395  -3.552  47.288  1.00 24.68  ? 401 HEM F CBA 1 
HETATM 14053 C  CGA . HEM N 2 .   ? 35.612  -2.435  47.865  1.00 25.54  ? 401 HEM F CGA 1 
HETATM 14054 O  O1A . HEM N 2 .   ? 35.678  -1.369  47.249  1.00 25.90  ? 401 HEM F O1A 1 
HETATM 14055 O  O2A . HEM N 2 .   ? 34.952  -2.561  48.909  1.00 28.32  ? 401 HEM F O2A 1 
HETATM 14056 C  C1B . HEM N 2 .   ? 42.325  0.233   46.983  1.00 31.68  ? 401 HEM F C1B 1 
HETATM 14057 C  C2B . HEM N 2 .   ? 43.506  0.708   46.315  1.00 30.85  ? 401 HEM F C2B 1 
HETATM 14058 C  C3B . HEM N 2 .   ? 43.953  1.787   46.986  1.00 31.00  ? 401 HEM F C3B 1 
HETATM 14059 C  C4B . HEM N 2 .   ? 43.059  1.986   48.125  1.00 29.28  ? 401 HEM F C4B 1 
HETATM 14060 C  CMB . HEM N 2 .   ? 44.174  0.139   45.113  1.00 35.23  ? 401 HEM F CMB 1 
HETATM 14061 C  CAB . HEM N 2 .   ? 45.170  2.603   46.901  1.00 39.56  ? 401 HEM F CAB 1 
HETATM 14062 C  CBB . HEM N 2 .   ? 46.308  2.103   46.447  1.00 42.42  ? 401 HEM F CBB 1 
HETATM 14063 C  C1C . HEM N 2 .   ? 42.366  3.328   50.012  1.00 23.61  ? 401 HEM F C1C 1 
HETATM 14064 C  C2C . HEM N 2 .   ? 42.530  4.319   50.970  1.00 23.61  ? 401 HEM F C2C 1 
HETATM 14065 C  C3C . HEM N 2 .   ? 41.440  4.278   51.769  1.00 22.03  ? 401 HEM F C3C 1 
HETATM 14066 C  C4C . HEM N 2 .   ? 40.641  3.190   51.318  1.00 22.42  ? 401 HEM F C4C 1 
HETATM 14067 C  CMC . HEM N 2 .   ? 43.696  5.264   51.046  1.00 23.89  ? 401 HEM F CMC 1 
HETATM 14068 C  CAC . HEM N 2 .   ? 41.049  5.106   52.915  1.00 24.76  ? 401 HEM F CAC 1 
HETATM 14069 C  CBC . HEM N 2 .   ? 41.649  6.193   53.328  1.00 27.21  ? 401 HEM F CBC 1 
HETATM 14070 C  C1D . HEM N 2 .   ? 38.772  1.720   51.581  1.00 23.82  ? 401 HEM F C1D 1 
HETATM 14071 C  C2D . HEM N 2 .   ? 37.515  1.369   52.259  1.00 24.68  ? 401 HEM F C2D 1 
HETATM 14072 C  C3D . HEM N 2 .   ? 37.109  0.190   51.731  1.00 27.09  ? 401 HEM F C3D 1 
HETATM 14073 C  C4D . HEM N 2 .   ? 38.158  -0.156  50.706  1.00 28.61  ? 401 HEM F C4D 1 
HETATM 14074 C  CMD . HEM N 2 .   ? 36.813  2.150   53.323  1.00 24.54  ? 401 HEM F CMD 1 
HETATM 14075 C  CAD . HEM N 2 .   ? 35.874  -0.653  52.097  1.00 28.64  ? 401 HEM F CAD 1 
HETATM 14076 C  CBD . HEM N 2 .   ? 35.862  -1.211  53.547  1.00 29.45  ? 401 HEM F CBD 1 
HETATM 14077 C  CGD . HEM N 2 .   ? 34.749  -2.201  53.839  1.00 30.29  ? 401 HEM F CGD 1 
HETATM 14078 O  O1D . HEM N 2 .   ? 34.907  -3.289  53.177  1.00 29.55  ? 401 HEM F O1D 1 
HETATM 14079 O  O2D . HEM N 2 .   ? 33.791  -1.919  54.696  1.00 33.64  ? 401 HEM F O2D 1 
HETATM 14080 N  NA  . HEM N 2 .   ? 39.920  -0.729  48.396  1.00 26.56  ? 401 HEM F NA  1 
HETATM 14081 N  NB  . HEM N 2 .   ? 42.101  1.018   48.045  1.00 30.83  ? 401 HEM F NB  1 
HETATM 14082 N  NC  . HEM N 2 .   ? 41.224  2.639   50.257  1.00 23.95  ? 401 HEM F NC  1 
HETATM 14083 N  ND  . HEM N 2 .   ? 39.139  0.812   50.654  1.00 27.14  ? 401 HEM F ND  1 
HETATM 14084 FE FE  . HEM N 2 .   ? 40.589  0.848   49.438  1.00 25.50  ? 401 HEM F FE  1 
HETATM 14085 O  O   . HOH O 5 .   ? -4.696  28.736  18.858  1.00 30.55  ? 501 HOH A O   1 
HETATM 14086 O  O   . HOH O 5 .   ? 12.185  30.139  2.887   1.00 23.43  ? 502 HOH A O   1 
HETATM 14087 O  O   . HOH O 5 .   ? -2.875  29.506  41.053  1.00 23.71  ? 503 HOH A O   1 
HETATM 14088 O  O   . HOH O 5 .   ? 13.352  29.625  24.863  0.65 23.08  ? 504 HOH A O   1 
HETATM 14089 O  O   . HOH O 5 .   ? 15.977  20.927  23.382  1.00 28.14  ? 505 HOH A O   1 
HETATM 14090 O  O   . HOH O 5 .   ? 7.118   18.538  12.552  1.00 20.04  ? 506 HOH A O   1 
HETATM 14091 O  O   . HOH O 5 .   ? 13.170  37.119  4.179   1.00 27.24  ? 507 HOH A O   1 
HETATM 14092 O  O   . HOH O 5 .   ? 9.397   29.130  8.421   1.00 16.54  ? 508 HOH A O   1 
HETATM 14093 O  O   . HOH O 5 .   ? 3.726   29.768  32.006  1.00 18.02  ? 509 HOH A O   1 
HETATM 14094 O  O   . HOH O 5 .   ? -0.453  26.410  19.348  1.00 21.31  ? 510 HOH A O   1 
HETATM 14095 O  O   . HOH O 5 .   ? -6.598  30.806  29.405  1.00 23.20  ? 511 HOH A O   1 
HETATM 14096 O  O   . HOH O 5 .   ? -11.940 33.526  30.519  1.00 22.26  ? 512 HOH A O   1 
HETATM 14097 O  O   . HOH O 5 .   ? 20.421  31.046  28.481  1.00 18.48  ? 513 HOH A O   1 
HETATM 14098 O  O   . HOH O 5 .   ? 12.919  32.013  5.020   1.00 23.82  ? 514 HOH A O   1 
HETATM 14099 O  O   . HOH O 5 .   ? 13.605  24.355  25.615  1.00 27.63  ? 515 HOH A O   1 
HETATM 14100 O  O   . HOH O 5 .   ? 13.785  21.063  24.424  1.00 28.28  ? 516 HOH A O   1 
HETATM 14101 O  O   . HOH O 5 .   ? 5.446   37.384  16.563  1.00 23.48  ? 517 HOH A O   1 
HETATM 14102 O  O   . HOH O 5 .   ? 12.165  32.163  0.781   1.00 39.91  ? 518 HOH A O   1 
HETATM 14103 O  O   . HOH O 5 .   ? -6.843  28.520  47.106  1.00 25.15  ? 519 HOH A O   1 
HETATM 14104 O  O   . HOH O 5 .   ? 15.482  33.321  32.713  1.00 25.24  ? 520 HOH A O   1 
HETATM 14105 O  O   . HOH O 5 .   ? 8.082   45.513  18.988  1.00 29.78  ? 521 HOH A O   1 
HETATM 14106 O  O   . HOH O 5 .   ? 8.130   19.377  24.734  1.00 20.18  ? 522 HOH A O   1 
HETATM 14107 O  O   . HOH O 5 .   ? -9.342  33.456  38.782  1.00 21.31  ? 523 HOH A O   1 
HETATM 14108 O  O   . HOH O 5 .   ? 14.162  28.754  31.564  1.00 24.01  ? 524 HOH A O   1 
HETATM 14109 O  O   . HOH O 5 .   ? 14.677  17.324  23.271  1.00 30.33  ? 525 HOH A O   1 
HETATM 14110 O  O   . HOH O 5 .   ? -10.436 28.364  27.333  1.00 24.56  ? 526 HOH A O   1 
HETATM 14111 O  O   . HOH O 5 .   ? 14.201  30.838  33.587  1.00 24.37  ? 527 HOH A O   1 
HETATM 14112 O  O   . HOH P 5 .   ? 22.193  -33.316 24.554  1.00 24.75  ? 501 HOH B O   1 
HETATM 14113 O  O   . HOH P 5 .   ? 42.043  -21.405 23.329  1.00 16.53  ? 502 HOH B O   1 
HETATM 14114 O  O   . HOH P 5 .   ? 45.910  -35.921 32.021  1.00 30.14  ? 503 HOH B O   1 
HETATM 14115 O  O   . HOH P 5 .   ? 24.549  -21.646 21.807  1.00 23.58  ? 504 HOH B O   1 
HETATM 14116 O  O   . HOH P 5 .   ? 37.220  -23.375 18.622  1.00 25.21  ? 505 HOH B O   1 
HETATM 14117 O  O   . HOH P 5 .   ? 32.141  -21.399 23.074  1.00 29.06  ? 506 HOH B O   1 
HETATM 14118 O  O   . HOH Q 5 .   ? 3.720   -4.285  2.322   0.65 25.72  ? 501 HOH C O   1 
HETATM 14119 O  O   . HOH Q 5 .   ? 8.038   6.347   -14.112 1.00 27.67  ? 502 HOH C O   1 
HETATM 14120 O  O   . HOH Q 5 .   ? 7.632   -2.144  9.398   1.00 27.05  ? 503 HOH C O   1 
HETATM 14121 O  O   . HOH Q 5 .   ? 3.571   9.633   -2.923  1.00 18.21  ? 504 HOH C O   1 
HETATM 14122 O  O   . HOH Q 5 .   ? -7.171  7.635   7.577   1.00 25.70  ? 505 HOH C O   1 
HETATM 14123 O  O   . HOH Q 5 .   ? 25.620  11.956  -5.944  1.00 32.70  ? 506 HOH C O   1 
HETATM 14124 O  O   . HOH Q 5 .   ? 8.869   -0.923  7.659   1.00 28.98  ? 507 HOH C O   1 
HETATM 14125 O  O   . HOH Q 5 .   ? 3.630   -12.163 4.772   1.00 18.64  ? 508 HOH C O   1 
HETATM 14126 O  O   . HOH Q 5 .   ? 5.208   7.157   -12.438 1.00 26.21  ? 509 HOH C O   1 
HETATM 14127 O  O   . HOH Q 5 .   ? 17.550  12.550  18.383  1.00 27.37  ? 510 HOH C O   1 
HETATM 14128 O  O   . HOH R 5 .   ? 43.105  14.733  7.822   0.55 25.34  ? 501 HOH D O   1 
HETATM 14129 O  O   . HOH R 5 .   ? 48.799  23.090  21.780  1.00 24.12  ? 502 HOH D O   1 
HETATM 14130 O  O   . HOH R 5 .   ? 54.281  10.323  16.585  1.00 25.98  ? 503 HOH D O   1 
HETATM 14131 O  O   . HOH R 5 .   ? 49.028  29.805  2.409   1.00 19.53  ? 504 HOH D O   1 
HETATM 14132 O  O   . HOH R 5 .   ? 45.654  12.843  25.599  1.00 21.83  ? 505 HOH D O   1 
HETATM 14133 O  O   . HOH R 5 .   ? 38.982  10.087  13.778  1.00 35.45  ? 506 HOH D O   1 
HETATM 14134 O  O   . HOH R 5 .   ? 60.261  3.716   7.141   1.00 27.40  ? 507 HOH D O   1 
HETATM 14135 O  O   . HOH R 5 .   ? 40.293  11.629  10.462  1.00 26.03  ? 508 HOH D O   1 
HETATM 14136 O  O   . HOH R 5 .   ? 55.986  26.328  3.951   1.00 18.82  ? 509 HOH D O   1 
HETATM 14137 O  O   . HOH R 5 .   ? 36.765  17.028  3.405   1.00 20.56  ? 510 HOH D O   1 
HETATM 14138 O  O   . HOH R 5 .   ? 55.124  28.818  2.502   1.00 22.81  ? 511 HOH D O   1 
HETATM 14139 O  O   . HOH R 5 .   ? 62.715  1.486   11.007  1.00 19.18  ? 512 HOH D O   1 
HETATM 14140 O  O   . HOH R 5 .   ? 40.633  10.766  3.666   1.00 21.23  ? 513 HOH D O   1 
HETATM 14141 O  O   . HOH R 5 .   ? 55.715  26.764  -3.448  1.00 22.21  ? 514 HOH D O   1 
HETATM 14142 O  O   . HOH R 5 .   ? 54.014  28.818  -3.206  1.00 30.91  ? 515 HOH D O   1 
HETATM 14143 O  O   . HOH R 5 .   ? 40.651  11.125  0.549   1.00 26.86  ? 516 HOH D O   1 
HETATM 14144 O  O   . HOH S 5 .   ? 3.652   -6.142  60.348  1.00 25.50  ? 501 HOH E O   1 
HETATM 14145 O  O   . HOH S 5 .   ? 10.575  -26.710 58.234  1.00 20.05  ? 502 HOH E O   1 
HETATM 14146 O  O   . HOH S 5 .   ? 1.293   -25.973 31.700  1.00 29.82  ? 503 HOH E O   1 
HETATM 14147 O  O   . HOH S 5 .   ? 16.068  -27.971 64.193  1.00 27.75  ? 504 HOH E O   1 
HETATM 14148 O  O   . HOH S 5 .   ? 8.283   -20.893 58.071  1.00 24.32  ? 505 HOH E O   1 
HETATM 14149 O  O   . HOH S 5 .   ? 10.096  -24.134 60.317  1.00 23.35  ? 506 HOH E O   1 
HETATM 14150 O  O   . HOH S 5 .   ? 7.891   -22.608 65.176  1.00 29.85  ? 507 HOH E O   1 
HETATM 14151 O  O   . HOH T 5 .   ? 46.946  14.621  43.560  1.00 22.51  ? 501 HOH F O   1 
HETATM 14152 O  O   . HOH T 5 .   ? 34.033  2.996   51.003  1.00 25.33  ? 502 HOH F O   1 
HETATM 14153 O  O   . HOH T 5 .   ? 39.543  2.116   47.926  0.60 28.66  ? 503 HOH F O   1 
HETATM 14154 O  O   . HOH T 5 .   ? 28.791  19.374  40.943  1.00 23.80  ? 504 HOH F O   1 
HETATM 14155 O  O   . HOH T 5 .   ? 29.273  28.024  40.299  1.00 24.32  ? 505 HOH F O   1 
HETATM 14156 O  O   . HOH T 5 .   ? 45.768  -18.894 44.366  1.00 27.59  ? 506 HOH F O   1 
HETATM 14157 O  O   . HOH T 5 .   ? 33.304  2.849   53.905  1.00 27.21  ? 507 HOH F O   1 
# 
