data_9F7Q
# 
_entry.id   9F7Q 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9F7Q         pdb_00009f7q 10.2210/pdb9f7q/pdb 
WWPDB D_1292136920 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-05-14 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9F7Q 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-04 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              acamara@ual.es 
_pdbx_contact_author.name_first         ana 
_pdbx_contact_author.name_last          camara-artigas 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2197-726X 
# 
_audit_author.name               'Camara-Artigas, A.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0003-2197-726X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'SARS-CoV-2 papain-like protease (PLpro) C112S mutant' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
_citation_author.citation_id        primary 
_citation_author.name               'Camara-Artigas, A.' 
_citation_author.ordinal            1 
_citation_author.identifier_ORCID   0000-0003-2197-726X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Replicase polyprotein 1ab' 36912.844 1  3.4.19.12,3.4.22.- C112S ? ? 
2 non-polymer syn 'ZINC ION'                  65.409    1  ?                  ?     ? ? 
3 non-polymer syn GLYCEROL                    92.094    1  ?                  ?     ? ? 
4 non-polymer syn 'SULFATE ION'               96.063    8  ?                  ?     ? ? 
5 water       nat water                       18.015    67 ?                  ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSF
LGRYMSALNHTKKWKYPQVNGLTSIKWADNNSYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV
GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQES
PFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTH
HHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSF
LGRYMSALNHTKKWKYPQVNGLTSIKWADNNSYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV
GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQES
PFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTH
HHHHH
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'ZINC ION'    ZN  
3 GLYCEROL      GOL 
4 'SULFATE ION' SO4 
5 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   VAL n 
1 4   ARG n 
1 5   THR n 
1 6   ILE n 
1 7   LYS n 
1 8   VAL n 
1 9   PHE n 
1 10  THR n 
1 11  THR n 
1 12  VAL n 
1 13  ASP n 
1 14  ASN n 
1 15  ILE n 
1 16  ASN n 
1 17  LEU n 
1 18  HIS n 
1 19  THR n 
1 20  GLN n 
1 21  VAL n 
1 22  VAL n 
1 23  ASP n 
1 24  MET n 
1 25  SER n 
1 26  MET n 
1 27  THR n 
1 28  TYR n 
1 29  GLY n 
1 30  GLN n 
1 31  GLN n 
1 32  PHE n 
1 33  GLY n 
1 34  PRO n 
1 35  THR n 
1 36  TYR n 
1 37  LEU n 
1 38  ASP n 
1 39  GLY n 
1 40  ALA n 
1 41  ASP n 
1 42  VAL n 
1 43  THR n 
1 44  LYS n 
1 45  ILE n 
1 46  LYS n 
1 47  PRO n 
1 48  HIS n 
1 49  ASN n 
1 50  SER n 
1 51  HIS n 
1 52  GLU n 
1 53  GLY n 
1 54  LYS n 
1 55  THR n 
1 56  PHE n 
1 57  TYR n 
1 58  VAL n 
1 59  LEU n 
1 60  PRO n 
1 61  ASN n 
1 62  ASP n 
1 63  ASP n 
1 64  THR n 
1 65  LEU n 
1 66  ARG n 
1 67  VAL n 
1 68  GLU n 
1 69  ALA n 
1 70  PHE n 
1 71  GLU n 
1 72  TYR n 
1 73  TYR n 
1 74  HIS n 
1 75  THR n 
1 76  THR n 
1 77  ASP n 
1 78  PRO n 
1 79  SER n 
1 80  PHE n 
1 81  LEU n 
1 82  GLY n 
1 83  ARG n 
1 84  TYR n 
1 85  MET n 
1 86  SER n 
1 87  ALA n 
1 88  LEU n 
1 89  ASN n 
1 90  HIS n 
1 91  THR n 
1 92  LYS n 
1 93  LYS n 
1 94  TRP n 
1 95  LYS n 
1 96  TYR n 
1 97  PRO n 
1 98  GLN n 
1 99  VAL n 
1 100 ASN n 
1 101 GLY n 
1 102 LEU n 
1 103 THR n 
1 104 SER n 
1 105 ILE n 
1 106 LYS n 
1 107 TRP n 
1 108 ALA n 
1 109 ASP n 
1 110 ASN n 
1 111 ASN n 
1 112 SER n 
1 113 TYR n 
1 114 LEU n 
1 115 ALA n 
1 116 THR n 
1 117 ALA n 
1 118 LEU n 
1 119 LEU n 
1 120 THR n 
1 121 LEU n 
1 122 GLN n 
1 123 GLN n 
1 124 ILE n 
1 125 GLU n 
1 126 LEU n 
1 127 LYS n 
1 128 PHE n 
1 129 ASN n 
1 130 PRO n 
1 131 PRO n 
1 132 ALA n 
1 133 LEU n 
1 134 GLN n 
1 135 ASP n 
1 136 ALA n 
1 137 TYR n 
1 138 TYR n 
1 139 ARG n 
1 140 ALA n 
1 141 ARG n 
1 142 ALA n 
1 143 GLY n 
1 144 GLU n 
1 145 ALA n 
1 146 ALA n 
1 147 ASN n 
1 148 PHE n 
1 149 CYS n 
1 150 ALA n 
1 151 LEU n 
1 152 ILE n 
1 153 LEU n 
1 154 ALA n 
1 155 TYR n 
1 156 CYS n 
1 157 ASN n 
1 158 LYS n 
1 159 THR n 
1 160 VAL n 
1 161 GLY n 
1 162 GLU n 
1 163 LEU n 
1 164 GLY n 
1 165 ASP n 
1 166 VAL n 
1 167 ARG n 
1 168 GLU n 
1 169 THR n 
1 170 MET n 
1 171 SER n 
1 172 TYR n 
1 173 LEU n 
1 174 PHE n 
1 175 GLN n 
1 176 HIS n 
1 177 ALA n 
1 178 ASN n 
1 179 LEU n 
1 180 ASP n 
1 181 SER n 
1 182 CYS n 
1 183 LYS n 
1 184 ARG n 
1 185 VAL n 
1 186 LEU n 
1 187 ASN n 
1 188 VAL n 
1 189 VAL n 
1 190 CYS n 
1 191 LYS n 
1 192 THR n 
1 193 CYS n 
1 194 GLY n 
1 195 GLN n 
1 196 GLN n 
1 197 GLN n 
1 198 THR n 
1 199 THR n 
1 200 LEU n 
1 201 LYS n 
1 202 GLY n 
1 203 VAL n 
1 204 GLU n 
1 205 ALA n 
1 206 VAL n 
1 207 MET n 
1 208 TYR n 
1 209 MET n 
1 210 GLY n 
1 211 THR n 
1 212 LEU n 
1 213 SER n 
1 214 TYR n 
1 215 GLU n 
1 216 GLN n 
1 217 PHE n 
1 218 LYS n 
1 219 LYS n 
1 220 GLY n 
1 221 VAL n 
1 222 GLN n 
1 223 ILE n 
1 224 PRO n 
1 225 CYS n 
1 226 THR n 
1 227 CYS n 
1 228 GLY n 
1 229 LYS n 
1 230 GLN n 
1 231 ALA n 
1 232 THR n 
1 233 LYS n 
1 234 TYR n 
1 235 LEU n 
1 236 VAL n 
1 237 GLN n 
1 238 GLN n 
1 239 GLU n 
1 240 SER n 
1 241 PRO n 
1 242 PHE n 
1 243 VAL n 
1 244 MET n 
1 245 MET n 
1 246 SER n 
1 247 ALA n 
1 248 PRO n 
1 249 PRO n 
1 250 ALA n 
1 251 GLN n 
1 252 TYR n 
1 253 GLU n 
1 254 LEU n 
1 255 LYS n 
1 256 HIS n 
1 257 GLY n 
1 258 THR n 
1 259 PHE n 
1 260 THR n 
1 261 CYS n 
1 262 ALA n 
1 263 SER n 
1 264 GLU n 
1 265 TYR n 
1 266 THR n 
1 267 GLY n 
1 268 ASN n 
1 269 TYR n 
1 270 GLN n 
1 271 CYS n 
1 272 GLY n 
1 273 HIS n 
1 274 TYR n 
1 275 LYS n 
1 276 HIS n 
1 277 ILE n 
1 278 THR n 
1 279 SER n 
1 280 LYS n 
1 281 GLU n 
1 282 THR n 
1 283 LEU n 
1 284 TYR n 
1 285 CYS n 
1 286 ILE n 
1 287 ASP n 
1 288 GLY n 
1 289 ALA n 
1 290 LEU n 
1 291 LEU n 
1 292 THR n 
1 293 LYS n 
1 294 SER n 
1 295 SER n 
1 296 GLU n 
1 297 TYR n 
1 298 LYS n 
1 299 GLY n 
1 300 PRO n 
1 301 ILE n 
1 302 THR n 
1 303 ASP n 
1 304 VAL n 
1 305 PHE n 
1 306 TYR n 
1 307 LYS n 
1 308 GLU n 
1 309 ASN n 
1 310 SER n 
1 311 TYR n 
1 312 THR n 
1 313 THR n 
1 314 THR n 
1 315 ILE n 
1 316 LYS n 
1 317 PRO n 
1 318 VAL n 
1 319 THR n 
1 320 HIS n 
1 321 HIS n 
1 322 HIS n 
1 323 HIS n 
1 324 HIS n 
1 325 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   325 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'rep, 1a-1b' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Severe acute respiratory syndrome coronavirus 2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2697049 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                               'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?                               'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                               'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                               'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ?                               'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ?                               'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                               'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?                               'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL        'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE       ?                               'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ?                               'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ?                               'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?                               'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?                               'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?                               'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?                               'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?                               'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ?                               'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ?                               'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ?                               'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                               'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?                               'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ?                               'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'      ?                               'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLU 2   2   ?   ?   ?   A . n 
A 1 3   VAL 3   3   3   VAL VAL A . n 
A 1 4   ARG 4   4   4   ARG ARG A . n 
A 1 5   THR 5   5   5   THR THR A . n 
A 1 6   ILE 6   6   6   ILE ILE A . n 
A 1 7   LYS 7   7   7   LYS LYS A . n 
A 1 8   VAL 8   8   8   VAL VAL A . n 
A 1 9   PHE 9   9   9   PHE PHE A . n 
A 1 10  THR 10  10  10  THR THR A . n 
A 1 11  THR 11  11  11  THR THR A . n 
A 1 12  VAL 12  12  12  VAL VAL A . n 
A 1 13  ASP 13  13  13  ASP ASP A . n 
A 1 14  ASN 14  14  14  ASN ASN A . n 
A 1 15  ILE 15  15  15  ILE ILE A . n 
A 1 16  ASN 16  16  16  ASN ASN A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  HIS 18  18  18  HIS HIS A . n 
A 1 19  THR 19  19  19  THR THR A . n 
A 1 20  GLN 20  20  20  GLN GLN A . n 
A 1 21  VAL 21  21  21  VAL VAL A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  ASP 23  23  23  ASP ASP A . n 
A 1 24  MET 24  24  24  MET MET A . n 
A 1 25  SER 25  25  25  SER SER A . n 
A 1 26  MET 26  26  26  MET MET A . n 
A 1 27  THR 27  27  27  THR THR A . n 
A 1 28  TYR 28  28  28  TYR TYR A . n 
A 1 29  GLY 29  29  29  GLY GLY A . n 
A 1 30  GLN 30  30  30  GLN GLN A . n 
A 1 31  GLN 31  31  31  GLN GLN A . n 
A 1 32  PHE 32  32  32  PHE PHE A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  PRO 34  34  34  PRO PRO A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  TYR 36  36  36  TYR TYR A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  ASP 38  38  38  ASP ASP A . n 
A 1 39  GLY 39  39  39  GLY GLY A . n 
A 1 40  ALA 40  40  40  ALA ALA A . n 
A 1 41  ASP 41  41  41  ASP ASP A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  THR 43  43  43  THR THR A . n 
A 1 44  LYS 44  44  44  LYS LYS A . n 
A 1 45  ILE 45  45  45  ILE ILE A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  HIS 48  48  48  HIS HIS A . n 
A 1 49  ASN 49  49  49  ASN ASN A . n 
A 1 50  SER 50  50  50  SER SER A . n 
A 1 51  HIS 51  51  51  HIS HIS A . n 
A 1 52  GLU 52  52  52  GLU GLU A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  LYS 54  54  54  LYS LYS A . n 
A 1 55  THR 55  55  55  THR THR A . n 
A 1 56  PHE 56  56  56  PHE PHE A . n 
A 1 57  TYR 57  57  57  TYR TYR A . n 
A 1 58  VAL 58  58  58  VAL VAL A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  PRO 60  60  60  PRO PRO A . n 
A 1 61  ASN 61  61  61  ASN ASN A . n 
A 1 62  ASP 62  62  62  ASP ASP A . n 
A 1 63  ASP 63  63  63  ASP ASP A . n 
A 1 64  THR 64  64  64  THR THR A . n 
A 1 65  LEU 65  65  65  LEU LEU A . n 
A 1 66  ARG 66  66  66  ARG ARG A . n 
A 1 67  VAL 67  67  67  VAL VAL A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  PHE 70  70  70  PHE PHE A . n 
A 1 71  GLU 71  71  71  GLU GLU A . n 
A 1 72  TYR 72  72  72  TYR TYR A . n 
A 1 73  TYR 73  73  73  TYR TYR A . n 
A 1 74  HIS 74  74  74  HIS HIS A . n 
A 1 75  THR 75  75  75  THR THR A . n 
A 1 76  THR 76  76  76  THR THR A . n 
A 1 77  ASP 77  77  77  ASP ASP A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  PHE 80  80  80  PHE PHE A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  GLY 82  82  82  GLY GLY A . n 
A 1 83  ARG 83  83  83  ARG ARG A . n 
A 1 84  TYR 84  84  84  TYR TYR A . n 
A 1 85  MET 85  85  85  MET MET A . n 
A 1 86  SER 86  86  86  SER SER A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  ASN 89  89  89  ASN ASN A . n 
A 1 90  HIS 90  90  90  HIS HIS A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  LYS 92  92  92  LYS LYS A . n 
A 1 93  LYS 93  93  93  LYS LYS A . n 
A 1 94  TRP 94  94  94  TRP TRP A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  TYR 96  96  96  TYR TYR A . n 
A 1 97  PRO 97  97  97  PRO PRO A . n 
A 1 98  GLN 98  98  98  GLN GLN A . n 
A 1 99  VAL 99  99  99  VAL VAL A . n 
A 1 100 ASN 100 100 100 ASN ASN A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 LEU 102 102 102 LEU LEU A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 SER 104 104 104 SER SER A . n 
A 1 105 ILE 105 105 105 ILE ILE A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 TRP 107 107 107 TRP TRP A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 ASP 109 109 109 ASP ASP A . n 
A 1 110 ASN 110 110 110 ASN ASN A . n 
A 1 111 ASN 111 111 111 ASN ASN A . n 
A 1 112 SER 112 112 112 SER SER A . n 
A 1 113 TYR 113 113 113 TYR TYR A . n 
A 1 114 LEU 114 114 114 LEU LEU A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 THR 116 116 116 THR THR A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 GLN 122 122 122 GLN GLN A . n 
A 1 123 GLN 123 123 123 GLN GLN A . n 
A 1 124 ILE 124 124 124 ILE ILE A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 LYS 127 127 127 LYS LYS A . n 
A 1 128 PHE 128 128 128 PHE PHE A . n 
A 1 129 ASN 129 129 129 ASN ASN A . n 
A 1 130 PRO 130 130 130 PRO PRO A . n 
A 1 131 PRO 131 131 131 PRO PRO A . n 
A 1 132 ALA 132 132 132 ALA ALA A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 GLN 134 134 134 GLN GLN A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 ALA 136 136 136 ALA ALA A . n 
A 1 137 TYR 137 137 137 TYR TYR A . n 
A 1 138 TYR 138 138 138 TYR TYR A . n 
A 1 139 ARG 139 139 139 ARG ARG A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 ARG 141 141 141 ARG ARG A . n 
A 1 142 ALA 142 142 142 ALA ALA A . n 
A 1 143 GLY 143 143 143 GLY GLY A . n 
A 1 144 GLU 144 144 144 GLU GLU A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 ASN 147 147 147 ASN ASN A . n 
A 1 148 PHE 148 148 148 PHE PHE A . n 
A 1 149 CYS 149 149 149 CYS CYS A . n 
A 1 150 ALA 150 150 150 ALA ALA A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 TYR 155 155 155 TYR TYR A . n 
A 1 156 CYS 156 156 156 CYS CYS A . n 
A 1 157 ASN 157 157 157 ASN ASN A . n 
A 1 158 LYS 158 158 158 LYS LYS A . n 
A 1 159 THR 159 159 159 THR THR A . n 
A 1 160 VAL 160 160 160 VAL VAL A . n 
A 1 161 GLY 161 161 161 GLY GLY A . n 
A 1 162 GLU 162 162 162 GLU GLU A . n 
A 1 163 LEU 163 163 163 LEU LEU A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 ARG 167 167 167 ARG ARG A . n 
A 1 168 GLU 168 168 168 GLU GLU A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 MET 170 170 170 MET MET A . n 
A 1 171 SER 171 171 171 SER SER A . n 
A 1 172 TYR 172 172 172 TYR TYR A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 PHE 174 174 174 PHE PHE A . n 
A 1 175 GLN 175 175 175 GLN GLN A . n 
A 1 176 HIS 176 176 176 HIS HIS A . n 
A 1 177 ALA 177 177 177 ALA ALA A . n 
A 1 178 ASN 178 178 178 ASN ASN A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 ASP 180 180 180 ASP ASP A . n 
A 1 181 SER 181 181 181 SER SER A . n 
A 1 182 CYS 182 182 182 CYS CYS A . n 
A 1 183 LYS 183 183 183 LYS LYS A . n 
A 1 184 ARG 184 184 184 ARG ARG A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 ASN 187 187 187 ASN ASN A . n 
A 1 188 VAL 188 188 188 VAL VAL A . n 
A 1 189 VAL 189 189 189 VAL VAL A . n 
A 1 190 CYS 190 190 190 CYS CYS A . n 
A 1 191 LYS 191 191 191 LYS LYS A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 CYS 193 193 193 CYS CYS A . n 
A 1 194 GLY 194 194 194 GLY GLY A . n 
A 1 195 GLN 195 195 195 GLN GLN A . n 
A 1 196 GLN 196 196 196 GLN GLN A . n 
A 1 197 GLN 197 197 197 GLN GLN A . n 
A 1 198 THR 198 198 198 THR THR A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 LEU 200 200 200 LEU LEU A . n 
A 1 201 LYS 201 201 201 LYS LYS A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 VAL 203 203 203 VAL VAL A . n 
A 1 204 GLU 204 204 204 GLU GLU A . n 
A 1 205 ALA 205 205 205 ALA ALA A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 MET 207 207 207 MET MET A . n 
A 1 208 TYR 208 208 208 TYR TYR A . n 
A 1 209 MET 209 209 209 MET MET A . n 
A 1 210 GLY 210 210 210 GLY GLY A . n 
A 1 211 THR 211 211 211 THR THR A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 SER 213 213 213 SER SER A . n 
A 1 214 TYR 214 214 214 TYR TYR A . n 
A 1 215 GLU 215 215 215 GLU GLU A . n 
A 1 216 GLN 216 216 216 GLN GLN A . n 
A 1 217 PHE 217 217 217 PHE PHE A . n 
A 1 218 LYS 218 218 218 LYS LYS A . n 
A 1 219 LYS 219 219 219 LYS LYS A . n 
A 1 220 GLY 220 220 220 GLY GLY A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 GLN 222 222 222 GLN GLN A . n 
A 1 223 ILE 223 223 223 ILE ILE A . n 
A 1 224 PRO 224 224 224 PRO PRO A . n 
A 1 225 CYS 225 225 225 CYS CYS A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 CYS 227 227 227 CYS CYS A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 LYS 229 229 229 LYS LYS A . n 
A 1 230 GLN 230 230 230 GLN GLN A . n 
A 1 231 ALA 231 231 231 ALA ALA A . n 
A 1 232 THR 232 232 232 THR THR A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 TYR 234 234 234 TYR TYR A . n 
A 1 235 LEU 235 235 235 LEU LEU A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 GLN 237 237 237 GLN GLN A . n 
A 1 238 GLN 238 238 238 GLN GLN A . n 
A 1 239 GLU 239 239 239 GLU GLU A . n 
A 1 240 SER 240 240 240 SER SER A . n 
A 1 241 PRO 241 241 241 PRO PRO A . n 
A 1 242 PHE 242 242 242 PHE PHE A . n 
A 1 243 VAL 243 243 243 VAL VAL A . n 
A 1 244 MET 244 244 244 MET MET A . n 
A 1 245 MET 245 245 245 MET MET A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 ALA 247 247 247 ALA ALA A . n 
A 1 248 PRO 248 248 248 PRO PRO A . n 
A 1 249 PRO 249 249 249 PRO PRO A . n 
A 1 250 ALA 250 250 250 ALA ALA A . n 
A 1 251 GLN 251 251 251 GLN GLN A . n 
A 1 252 TYR 252 252 252 TYR TYR A . n 
A 1 253 GLU 253 253 253 GLU GLU A . n 
A 1 254 LEU 254 254 254 LEU LEU A . n 
A 1 255 LYS 255 255 255 LYS LYS A . n 
A 1 256 HIS 256 256 256 HIS HIS A . n 
A 1 257 GLY 257 257 257 GLY GLY A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 PHE 259 259 259 PHE PHE A . n 
A 1 260 THR 260 260 260 THR THR A . n 
A 1 261 CYS 261 261 261 CYS CYS A . n 
A 1 262 ALA 262 262 262 ALA ALA A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 GLU 264 264 264 GLU GLU A . n 
A 1 265 TYR 265 265 265 TYR TYR A . n 
A 1 266 THR 266 266 266 THR THR A . n 
A 1 267 GLY 267 267 267 GLY GLY A . n 
A 1 268 ASN 268 268 268 ASN ASN A . n 
A 1 269 TYR 269 269 269 TYR TYR A . n 
A 1 270 GLN 270 270 270 GLN GLN A . n 
A 1 271 CYS 271 271 271 CYS CYS A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 HIS 273 273 273 HIS HIS A . n 
A 1 274 TYR 274 274 274 TYR TYR A . n 
A 1 275 LYS 275 275 275 LYS LYS A . n 
A 1 276 HIS 276 276 276 HIS HIS A . n 
A 1 277 ILE 277 277 277 ILE ILE A . n 
A 1 278 THR 278 278 278 THR THR A . n 
A 1 279 SER 279 279 279 SER SER A . n 
A 1 280 LYS 280 280 280 LYS LYS A . n 
A 1 281 GLU 281 281 281 GLU GLU A . n 
A 1 282 THR 282 282 282 THR THR A . n 
A 1 283 LEU 283 283 283 LEU LEU A . n 
A 1 284 TYR 284 284 284 TYR TYR A . n 
A 1 285 CYS 285 285 285 CYS CYS A . n 
A 1 286 ILE 286 286 286 ILE ILE A . n 
A 1 287 ASP 287 287 287 ASP ASP A . n 
A 1 288 GLY 288 288 288 GLY GLY A . n 
A 1 289 ALA 289 289 289 ALA ALA A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 LEU 291 291 291 LEU LEU A . n 
A 1 292 THR 292 292 292 THR THR A . n 
A 1 293 LYS 293 293 293 LYS LYS A . n 
A 1 294 SER 294 294 294 SER SER A . n 
A 1 295 SER 295 295 295 SER SER A . n 
A 1 296 GLU 296 296 296 GLU GLU A . n 
A 1 297 TYR 297 297 297 TYR TYR A . n 
A 1 298 LYS 298 298 298 LYS LYS A . n 
A 1 299 GLY 299 299 299 GLY GLY A . n 
A 1 300 PRO 300 300 300 PRO PRO A . n 
A 1 301 ILE 301 301 301 ILE ILE A . n 
A 1 302 THR 302 302 302 THR THR A . n 
A 1 303 ASP 303 303 303 ASP ASP A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 PHE 305 305 305 PHE PHE A . n 
A 1 306 TYR 306 306 306 TYR TYR A . n 
A 1 307 LYS 307 307 307 LYS LYS A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 ASN 309 309 309 ASN ASN A . n 
A 1 310 SER 310 310 310 SER SER A . n 
A 1 311 TYR 311 311 311 TYR TYR A . n 
A 1 312 THR 312 312 312 THR THR A . n 
A 1 313 THR 313 313 313 THR THR A . n 
A 1 314 THR 314 314 314 THR THR A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 LYS 316 316 316 LYS LYS A . n 
A 1 317 PRO 317 317 ?   ?   ?   A . n 
A 1 318 VAL 318 318 ?   ?   ?   A . n 
A 1 319 THR 319 319 ?   ?   ?   A . n 
A 1 320 HIS 320 320 ?   ?   ?   A . n 
A 1 321 HIS 321 321 ?   ?   ?   A . n 
A 1 322 HIS 322 322 ?   ?   ?   A . n 
A 1 323 HIS 323 323 ?   ?   ?   A . n 
A 1 324 HIS 324 324 ?   ?   ?   A . n 
A 1 325 HIS 325 325 ?   ?   ?   A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 ZN  1  401 401 ZN  ZN  A . 
C 3 GOL 1  402 402 GOL GOL A . 
D 4 SO4 1  403 1   SO4 SO4 A . 
E 4 SO4 1  404 3   SO4 SO4 A . 
F 4 SO4 1  405 4   SO4 SO4 A . 
G 4 SO4 1  406 5   SO4 SO4 A . 
H 4 SO4 1  407 6   SO4 SO4 A . 
I 4 SO4 1  408 7   SO4 SO4 A . 
J 4 SO4 1  409 8   SO4 SO4 A . 
K 4 SO4 1  410 9   SO4 SO4 A . 
L 5 HOH 1  501 56  HOH HOH A . 
L 5 HOH 2  502 45  HOH HOH A . 
L 5 HOH 3  503 53  HOH HOH A . 
L 5 HOH 4  504 41  HOH HOH A . 
L 5 HOH 5  505 21  HOH HOH A . 
L 5 HOH 6  506 11  HOH HOH A . 
L 5 HOH 7  507 48  HOH HOH A . 
L 5 HOH 8  508 66  HOH HOH A . 
L 5 HOH 9  509 3   HOH HOH A . 
L 5 HOH 10 510 19  HOH HOH A . 
L 5 HOH 11 511 23  HOH HOH A . 
L 5 HOH 12 512 8   HOH HOH A . 
L 5 HOH 13 513 15  HOH HOH A . 
L 5 HOH 14 514 5   HOH HOH A . 
L 5 HOH 15 515 29  HOH HOH A . 
L 5 HOH 16 516 47  HOH HOH A . 
L 5 HOH 17 517 25  HOH HOH A . 
L 5 HOH 18 518 36  HOH HOH A . 
L 5 HOH 19 519 55  HOH HOH A . 
L 5 HOH 20 520 22  HOH HOH A . 
L 5 HOH 21 521 6   HOH HOH A . 
L 5 HOH 22 522 31  HOH HOH A . 
L 5 HOH 23 523 13  HOH HOH A . 
L 5 HOH 24 524 4   HOH HOH A . 
L 5 HOH 25 525 34  HOH HOH A . 
L 5 HOH 26 526 1   HOH HOH A . 
L 5 HOH 27 527 14  HOH HOH A . 
L 5 HOH 28 528 12  HOH HOH A . 
L 5 HOH 29 529 10  HOH HOH A . 
L 5 HOH 30 530 49  HOH HOH A . 
L 5 HOH 31 531 20  HOH HOH A . 
L 5 HOH 32 532 44  HOH HOH A . 
L 5 HOH 33 533 16  HOH HOH A . 
L 5 HOH 34 534 57  HOH HOH A . 
L 5 HOH 35 535 43  HOH HOH A . 
L 5 HOH 36 536 42  HOH HOH A . 
L 5 HOH 37 537 37  HOH HOH A . 
L 5 HOH 38 538 69  HOH HOH A . 
L 5 HOH 39 539 50  HOH HOH A . 
L 5 HOH 40 540 27  HOH HOH A . 
L 5 HOH 41 541 33  HOH HOH A . 
L 5 HOH 42 542 7   HOH HOH A . 
L 5 HOH 43 543 58  HOH HOH A . 
L 5 HOH 44 544 54  HOH HOH A . 
L 5 HOH 45 545 2   HOH HOH A . 
L 5 HOH 46 546 38  HOH HOH A . 
L 5 HOH 47 547 26  HOH HOH A . 
L 5 HOH 48 548 40  HOH HOH A . 
L 5 HOH 49 549 65  HOH HOH A . 
L 5 HOH 50 550 61  HOH HOH A . 
L 5 HOH 51 551 9   HOH HOH A . 
L 5 HOH 52 552 28  HOH HOH A . 
L 5 HOH 53 553 63  HOH HOH A . 
L 5 HOH 54 554 30  HOH HOH A . 
L 5 HOH 55 555 32  HOH HOH A . 
L 5 HOH 56 556 62  HOH HOH A . 
L 5 HOH 57 557 60  HOH HOH A . 
L 5 HOH 58 558 64  HOH HOH A . 
L 5 HOH 59 559 67  HOH HOH A . 
L 5 HOH 60 560 17  HOH HOH A . 
L 5 HOH 61 561 39  HOH HOH A . 
L 5 HOH 62 562 18  HOH HOH A . 
L 5 HOH 63 563 68  HOH HOH A . 
L 5 HOH 64 564 70  HOH HOH A . 
L 5 HOH 65 565 71  HOH HOH A . 
L 5 HOH 66 566 52  HOH HOH A . 
L 5 HOH 67 567 24  HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLN 30  ? CG  ? A GLN 30  CG  
2  1 Y 1 A GLN 30  ? CD  ? A GLN 30  CD  
3  1 Y 1 A GLN 30  ? OE1 ? A GLN 30  OE1 
4  1 Y 1 A GLN 30  ? NE2 ? A GLN 30  NE2 
5  1 Y 1 A GLU 204 ? CG  ? A GLU 204 CG  
6  1 Y 1 A GLU 204 ? CD  ? A GLU 204 CD  
7  1 Y 1 A GLU 204 ? OE1 ? A GLU 204 OE1 
8  1 Y 1 A GLU 204 ? OE2 ? A GLU 204 OE2 
9  1 Y 1 A LYS 316 ? CG  ? A LYS 316 CG  
10 1 Y 1 A LYS 316 ? CD  ? A LYS 316 CD  
11 1 Y 1 A LYS 316 ? CE  ? A LYS 316 CE  
12 1 Y 1 A LYS 316 ? NZ  ? A LYS 316 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.20_4459 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .         2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .         3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .         4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9F7Q 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     82.230 
_cell.length_a_esd                 ? 
_cell.length_b                     82.230 
_cell.length_b_esd                 ? 
_cell.length_c                     133.603 
_cell.length_c_esd                 ? 
_cell.volume                       782361.413 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9F7Q 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9F7Q 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.62 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          66.08 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2.5 M ammonium sulfate,0.1M MES' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            288 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-03-31 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97918 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ALBA BEAMLINE XALOC' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97918 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   XALOC 
_diffrn_source.pdbx_synchrotron_site       ALBA 
# 
_reflns.B_iso_Wilson_estimate                          52.43 
_reflns.entry_id                                       9F7Q 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.30 
_reflns.d_resolution_low                               19.75 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     23804 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                7.0 
_reflns.pdbx_netI_over_av_sigmaI                       12.6 
_reflns.pdbx_netI_over_sigmaI                          12.6 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.01 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.095 
_reflns.pdbx_Rpim_I_all                                0.036 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.088 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.30 
_reflns_shell.d_res_low                                     2.38 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.4 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2295 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               6.4 
_reflns_shell.pdbx_chi_squared                              0.98 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.540 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.619 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.256 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               62.23 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9F7Q 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.30 
_refine.ls_d_res_low                             19.75 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     23749 
_refine.ls_number_reflns_R_free                  1134 
_refine.ls_number_reflns_R_work                  22615 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.89 
_refine.ls_percent_reflns_R_free                 4.77 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2066 
_refine.ls_R_factor_R_free                       0.2315 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2054 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.05 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 26.9357 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2574 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.30 
_refine_hist.d_res_low                        19.75 
_refine_hist.number_atoms_solvent             67 
_refine_hist.number_atoms_total               2594 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2480 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         47 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0044  ? 2576 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.5684  ? 3500 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0402  ? 385  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0228  ? 437  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 17.2108 ? 919  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.30 2.40  . . 149 2750 99.93  . . . . 0.2908 . . . . . . . . . . . 0.2864 
'X-RAY DIFFRACTION' 2.40 2.53  . . 148 2768 99.79  . . . . 0.2625 . . . . . . . . . . . 0.3175 
'X-RAY DIFFRACTION' 2.53 2.69  . . 147 2789 99.93  . . . . 0.2843 . . . . . . . . . . . 0.2903 
'X-RAY DIFFRACTION' 2.69 2.90  . . 127 2814 99.90  . . . . 0.2436 . . . . . . . . . . . 0.2802 
'X-RAY DIFFRACTION' 2.90 3.19  . . 130 2818 99.90  . . . . 0.2722 . . . . . . . . . . . 0.2846 
'X-RAY DIFFRACTION' 3.19 3.65  . . 149 2825 100.00 . . . . 0.2024 . . . . . . . . . . . 0.2455 
'X-RAY DIFFRACTION' 3.65 4.58  . . 145 2868 99.97  . . . . 0.1640 . . . . . . . . . . . 0.2050 
'X-RAY DIFFRACTION' 4.58 19.75 . . 139 2983 99.74  . . . . 0.1812 . . . . . . . . . . . 0.1947 
# 
_struct.entry_id                     9F7Q 
_struct.title                        'SARS-CoV-2 papain-like protease (PLpro) C112S mutant' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9F7Q 
_struct_keywords.text            'Protease, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
K N N 4 ? 
L N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    R1AB_SARS2 
_struct_ref.pdbx_db_accession          P0DTD1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFL
GRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVG
ELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESP
FVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVT
;
_struct_ref.pdbx_align_begin           1564 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9F7Q 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 2 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 319 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P0DTD1 
_struct_ref_seq.db_align_beg                  1564 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1881 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       2 
_struct_ref_seq.pdbx_auth_seq_align_end       319 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9F7Q MET A 1   ? UNP P0DTD1 ?   ?    'initiating methionine' 1   1 
1 9F7Q SER A 112 ? UNP P0DTD1 CYS 1674 'engineered mutation'   112 2 
1 9F7Q HIS A 320 ? UNP P0DTD1 ?   ?    'expression tag'        320 3 
1 9F7Q HIS A 321 ? UNP P0DTD1 ?   ?    'expression tag'        321 4 
1 9F7Q HIS A 322 ? UNP P0DTD1 ?   ?    'expression tag'        322 5 
1 9F7Q HIS A 323 ? UNP P0DTD1 ?   ?    'expression tag'        323 6 
1 9F7Q HIS A 324 ? UNP P0DTD1 ?   ?    'expression tag'        324 7 
1 9F7Q HIS A 325 ? UNP P0DTD1 ?   ?    'expression tag'        325 8 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1340  ? 
1 MORE         -74   ? 
1 'SSA (A^2)'  15550 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'light scattering' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 27  ? GLY A 33  ? THR A 27  GLY A 33  1 ? 7  
HELX_P HELX_P2  AA2 HIS A 48  ? GLU A 52  ? HIS A 48  GLU A 52  5 ? 5  
HELX_P HELX_P3  AA3 ASP A 62  ? HIS A 74  ? ASP A 62  HIS A 74  1 ? 13 
HELX_P HELX_P4  AA4 SER A 79  ? LYS A 92  ? SER A 79  LYS A 92  1 ? 14 
HELX_P HELX_P5  AA5 ASN A 111 ? GLN A 122 ? ASN A 111 GLN A 122 1 ? 12 
HELX_P HELX_P6  AA6 PRO A 130 ? ALA A 142 ? PRO A 130 ALA A 142 1 ? 13 
HELX_P HELX_P7  AA7 ALA A 145 ? CYS A 156 ? ALA A 145 CYS A 156 1 ? 12 
HELX_P HELX_P8  AA8 ASP A 165 ? HIS A 176 ? ASP A 165 HIS A 176 1 ? 12 
HELX_P HELX_P9  AA9 VAL A 203 ? ALA A 205 ? VAL A 203 ALA A 205 5 ? 3  
HELX_P HELX_P10 AB1 SER A 213 ? GLY A 220 ? SER A 213 GLY A 220 1 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A CYS 190 SG ? ? ? 1_555 B ZN . ZN ? ? A CYS 190 A ZN 401 1_555 ? ? ? ? ? ? ? 2.329 ? ? 
metalc2 metalc ? ? A CYS 193 SG ? ? ? 1_555 B ZN . ZN ? ? A CYS 193 A ZN 401 1_555 ? ? ? ? ? ? ? 2.332 ? ? 
metalc3 metalc ? ? A CYS 225 SG ? ? ? 1_555 B ZN . ZN ? ? A CYS 225 A ZN 401 1_555 ? ? ? ? ? ? ? 2.327 ? ? 
metalc4 metalc ? ? A CYS 227 SG ? ? ? 1_555 B ZN . ZN ? ? A CYS 227 A ZN 401 1_555 ? ? ? ? ? ? ? 2.331 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 SG ? A CYS 190 ? A CYS 190 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 193 ? A CYS 193 ? 1_555 106.0 ? 
2 SG ? A CYS 190 ? A CYS 190 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 225 ? A CYS 225 ? 1_555 109.6 ? 
3 SG ? A CYS 193 ? A CYS 193 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 225 ? A CYS 225 ? 1_555 108.5 ? 
4 SG ? A CYS 190 ? A CYS 190 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 227 ? A CYS 227 ? 1_555 110.0 ? 
5 SG ? A CYS 193 ? A CYS 193 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 227 ? A CYS 227 ? 1_555 114.9 ? 
6 SG ? A CYS 225 ? A CYS 225 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 227 ? A CYS 227 ? 1_555 107.8 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 HIS A 18  ? ASP A 23  ? HIS A 18  ASP A 23  
AA1 2 THR A 5   ? THR A 11  ? THR A 5   THR A 11  
AA1 3 THR A 55  ? VAL A 58  ? THR A 55  VAL A 58  
AA1 4 THR A 35  ? LEU A 37  ? THR A 35  LEU A 37  
AA1 5 ALA A 40  ? ASP A 41  ? ALA A 40  ASP A 41  
AA2 1 GLN A 98  ? VAL A 99  ? GLN A 98  VAL A 99  
AA2 2 LEU A 102 ? THR A 103 ? LEU A 102 THR A 103 
AA3 1 GLY A 194 ? LYS A 201 ? GLY A 194 LYS A 201 
AA3 2 LYS A 183 ? CYS A 190 ? LYS A 183 CYS A 190 
AA3 3 GLN A 230 ? GLU A 239 ? GLN A 230 GLU A 239 
AA3 4 VAL A 221 ? PRO A 224 ? VAL A 221 PRO A 224 
AA4 1 GLY A 194 ? LYS A 201 ? GLY A 194 LYS A 201 
AA4 2 LYS A 183 ? CYS A 190 ? LYS A 183 CYS A 190 
AA4 3 GLN A 230 ? GLU A 239 ? GLN A 230 GLU A 239 
AA4 4 SER A 310 ? THR A 312 ? SER A 310 THR A 312 
AA5 1 MET A 207 ? MET A 209 ? MET A 207 MET A 209 
AA5 2 PHE A 242 ? LEU A 254 ? PHE A 242 LEU A 254 
AA5 3 TYR A 297 ? LYS A 307 ? TYR A 297 LYS A 307 
AA5 4 CYS A 261 ? GLY A 267 ? CYS A 261 GLY A 267 
AA5 5 GLY A 272 ? SER A 279 ? GLY A 272 SER A 279 
AA5 6 LEU A 283 ? ASP A 287 ? LEU A 283 ASP A 287 
AA5 7 LEU A 290 ? SER A 294 ? LEU A 290 SER A 294 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLN A 20  ? O GLN A 20  N VAL A 8   ? N VAL A 8   
AA1 2 3 N PHE A 9   ? N PHE A 9   O PHE A 56  ? O PHE A 56  
AA1 3 4 O TYR A 57  ? O TYR A 57  N TYR A 36  ? N TYR A 36  
AA1 4 5 N LEU A 37  ? N LEU A 37  O ALA A 40  ? O ALA A 40  
AA2 1 2 N VAL A 99  ? N VAL A 99  O LEU A 102 ? O LEU A 102 
AA3 1 2 O LEU A 200 ? O LEU A 200 N ARG A 184 ? N ARG A 184 
AA3 2 3 N VAL A 189 ? N VAL A 189 O THR A 232 ? O THR A 232 
AA3 3 4 O ALA A 231 ? O ALA A 231 N ILE A 223 ? N ILE A 223 
AA4 1 2 O LEU A 200 ? O LEU A 200 N ARG A 184 ? N ARG A 184 
AA4 2 3 N VAL A 189 ? N VAL A 189 O THR A 232 ? O THR A 232 
AA4 3 4 N GLN A 238 ? N GLN A 238 O TYR A 311 ? O TYR A 311 
AA5 1 2 N TYR A 208 ? N TYR A 208 O SER A 246 ? O SER A 246 
AA5 2 3 N MET A 245 ? N MET A 245 O VAL A 304 ? O VAL A 304 
AA5 3 4 O PHE A 305 ? O PHE A 305 N CYS A 261 ? N CYS A 261 
AA5 4 5 N GLU A 264 ? N GLU A 264 O LYS A 275 ? O LYS A 275 
AA5 5 6 N THR A 278 ? N THR A 278 O TYR A 284 ? O TYR A 284 
AA5 6 7 N CYS A 285 ? N CYS A 285 O THR A 292 ? O THR A 292 
# 
_pdbx_entry_details.entry_id                   9F7Q 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PRO A 60  ? ? -60.51  99.73   
2 1 SER A 104 ? ? -111.16 -167.75 
3 1 ALA A 108 ? ? -177.06 143.21  
4 1 GLN A 196 ? ? -160.86 105.87  
5 1 LYS A 280 ? ? -115.75 -133.92 
6 1 ASN A 309 ? ? -141.59 -62.16  
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     139 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.281 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A GLU 2   ? A GLU 2   
3  1 Y 1 A PRO 317 ? A PRO 317 
4  1 Y 1 A VAL 318 ? A VAL 318 
5  1 Y 1 A THR 319 ? A THR 319 
6  1 Y 1 A HIS 320 ? A HIS 320 
7  1 Y 1 A HIS 321 ? A HIS 321 
8  1 Y 1 A HIS 322 ? A HIS 322 
9  1 Y 1 A HIS 323 ? A HIS 323 
10 1 Y 1 A HIS 324 ? A HIS 324 
11 1 Y 1 A HIS 325 ? A HIS 325 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
GOL C1   C  N N 137 
GOL O1   O  N N 138 
GOL C2   C  N N 139 
GOL O2   O  N N 140 
GOL C3   C  N N 141 
GOL O3   O  N N 142 
GOL H11  H  N N 143 
GOL H12  H  N N 144 
GOL HO1  H  N N 145 
GOL H2   H  N N 146 
GOL HO2  H  N N 147 
GOL H31  H  N N 148 
GOL H32  H  N N 149 
GOL HO3  H  N N 150 
HIS N    N  N N 151 
HIS CA   C  N S 152 
HIS C    C  N N 153 
HIS O    O  N N 154 
HIS CB   C  N N 155 
HIS CG   C  Y N 156 
HIS ND1  N  Y N 157 
HIS CD2  C  Y N 158 
HIS CE1  C  Y N 159 
HIS NE2  N  Y N 160 
HIS OXT  O  N N 161 
HIS H    H  N N 162 
HIS H2   H  N N 163 
HIS HA   H  N N 164 
HIS HB2  H  N N 165 
HIS HB3  H  N N 166 
HIS HD1  H  N N 167 
HIS HD2  H  N N 168 
HIS HE1  H  N N 169 
HIS HE2  H  N N 170 
HIS HXT  H  N N 171 
HOH O    O  N N 172 
HOH H1   H  N N 173 
HOH H2   H  N N 174 
ILE N    N  N N 175 
ILE CA   C  N S 176 
ILE C    C  N N 177 
ILE O    O  N N 178 
ILE CB   C  N S 179 
ILE CG1  C  N N 180 
ILE CG2  C  N N 181 
ILE CD1  C  N N 182 
ILE OXT  O  N N 183 
ILE H    H  N N 184 
ILE H2   H  N N 185 
ILE HA   H  N N 186 
ILE HB   H  N N 187 
ILE HG12 H  N N 188 
ILE HG13 H  N N 189 
ILE HG21 H  N N 190 
ILE HG22 H  N N 191 
ILE HG23 H  N N 192 
ILE HD11 H  N N 193 
ILE HD12 H  N N 194 
ILE HD13 H  N N 195 
ILE HXT  H  N N 196 
LEU N    N  N N 197 
LEU CA   C  N S 198 
LEU C    C  N N 199 
LEU O    O  N N 200 
LEU CB   C  N N 201 
LEU CG   C  N N 202 
LEU CD1  C  N N 203 
LEU CD2  C  N N 204 
LEU OXT  O  N N 205 
LEU H    H  N N 206 
LEU H2   H  N N 207 
LEU HA   H  N N 208 
LEU HB2  H  N N 209 
LEU HB3  H  N N 210 
LEU HG   H  N N 211 
LEU HD11 H  N N 212 
LEU HD12 H  N N 213 
LEU HD13 H  N N 214 
LEU HD21 H  N N 215 
LEU HD22 H  N N 216 
LEU HD23 H  N N 217 
LEU HXT  H  N N 218 
LYS N    N  N N 219 
LYS CA   C  N S 220 
LYS C    C  N N 221 
LYS O    O  N N 222 
LYS CB   C  N N 223 
LYS CG   C  N N 224 
LYS CD   C  N N 225 
LYS CE   C  N N 226 
LYS NZ   N  N N 227 
LYS OXT  O  N N 228 
LYS H    H  N N 229 
LYS H2   H  N N 230 
LYS HA   H  N N 231 
LYS HB2  H  N N 232 
LYS HB3  H  N N 233 
LYS HG2  H  N N 234 
LYS HG3  H  N N 235 
LYS HD2  H  N N 236 
LYS HD3  H  N N 237 
LYS HE2  H  N N 238 
LYS HE3  H  N N 239 
LYS HZ1  H  N N 240 
LYS HZ2  H  N N 241 
LYS HZ3  H  N N 242 
LYS HXT  H  N N 243 
MET N    N  N N 244 
MET CA   C  N S 245 
MET C    C  N N 246 
MET O    O  N N 247 
MET CB   C  N N 248 
MET CG   C  N N 249 
MET SD   S  N N 250 
MET CE   C  N N 251 
MET OXT  O  N N 252 
MET H    H  N N 253 
MET H2   H  N N 254 
MET HA   H  N N 255 
MET HB2  H  N N 256 
MET HB3  H  N N 257 
MET HG2  H  N N 258 
MET HG3  H  N N 259 
MET HE1  H  N N 260 
MET HE2  H  N N 261 
MET HE3  H  N N 262 
MET HXT  H  N N 263 
PHE N    N  N N 264 
PHE CA   C  N S 265 
PHE C    C  N N 266 
PHE O    O  N N 267 
PHE CB   C  N N 268 
PHE CG   C  Y N 269 
PHE CD1  C  Y N 270 
PHE CD2  C  Y N 271 
PHE CE1  C  Y N 272 
PHE CE2  C  Y N 273 
PHE CZ   C  Y N 274 
PHE OXT  O  N N 275 
PHE H    H  N N 276 
PHE H2   H  N N 277 
PHE HA   H  N N 278 
PHE HB2  H  N N 279 
PHE HB3  H  N N 280 
PHE HD1  H  N N 281 
PHE HD2  H  N N 282 
PHE HE1  H  N N 283 
PHE HE2  H  N N 284 
PHE HZ   H  N N 285 
PHE HXT  H  N N 286 
PRO N    N  N N 287 
PRO CA   C  N S 288 
PRO C    C  N N 289 
PRO O    O  N N 290 
PRO CB   C  N N 291 
PRO CG   C  N N 292 
PRO CD   C  N N 293 
PRO OXT  O  N N 294 
PRO H    H  N N 295 
PRO HA   H  N N 296 
PRO HB2  H  N N 297 
PRO HB3  H  N N 298 
PRO HG2  H  N N 299 
PRO HG3  H  N N 300 
PRO HD2  H  N N 301 
PRO HD3  H  N N 302 
PRO HXT  H  N N 303 
SER N    N  N N 304 
SER CA   C  N S 305 
SER C    C  N N 306 
SER O    O  N N 307 
SER CB   C  N N 308 
SER OG   O  N N 309 
SER OXT  O  N N 310 
SER H    H  N N 311 
SER H2   H  N N 312 
SER HA   H  N N 313 
SER HB2  H  N N 314 
SER HB3  H  N N 315 
SER HG   H  N N 316 
SER HXT  H  N N 317 
SO4 S    S  N N 318 
SO4 O1   O  N N 319 
SO4 O2   O  N N 320 
SO4 O3   O  N N 321 
SO4 O4   O  N N 322 
THR N    N  N N 323 
THR CA   C  N S 324 
THR C    C  N N 325 
THR O    O  N N 326 
THR CB   C  N R 327 
THR OG1  O  N N 328 
THR CG2  C  N N 329 
THR OXT  O  N N 330 
THR H    H  N N 331 
THR H2   H  N N 332 
THR HA   H  N N 333 
THR HB   H  N N 334 
THR HG1  H  N N 335 
THR HG21 H  N N 336 
THR HG22 H  N N 337 
THR HG23 H  N N 338 
THR HXT  H  N N 339 
TRP N    N  N N 340 
TRP CA   C  N S 341 
TRP C    C  N N 342 
TRP O    O  N N 343 
TRP CB   C  N N 344 
TRP CG   C  Y N 345 
TRP CD1  C  Y N 346 
TRP CD2  C  Y N 347 
TRP NE1  N  Y N 348 
TRP CE2  C  Y N 349 
TRP CE3  C  Y N 350 
TRP CZ2  C  Y N 351 
TRP CZ3  C  Y N 352 
TRP CH2  C  Y N 353 
TRP OXT  O  N N 354 
TRP H    H  N N 355 
TRP H2   H  N N 356 
TRP HA   H  N N 357 
TRP HB2  H  N N 358 
TRP HB3  H  N N 359 
TRP HD1  H  N N 360 
TRP HE1  H  N N 361 
TRP HE3  H  N N 362 
TRP HZ2  H  N N 363 
TRP HZ3  H  N N 364 
TRP HH2  H  N N 365 
TRP HXT  H  N N 366 
TYR N    N  N N 367 
TYR CA   C  N S 368 
TYR C    C  N N 369 
TYR O    O  N N 370 
TYR CB   C  N N 371 
TYR CG   C  Y N 372 
TYR CD1  C  Y N 373 
TYR CD2  C  Y N 374 
TYR CE1  C  Y N 375 
TYR CE2  C  Y N 376 
TYR CZ   C  Y N 377 
TYR OH   O  N N 378 
TYR OXT  O  N N 379 
TYR H    H  N N 380 
TYR H2   H  N N 381 
TYR HA   H  N N 382 
TYR HB2  H  N N 383 
TYR HB3  H  N N 384 
TYR HD1  H  N N 385 
TYR HD2  H  N N 386 
TYR HE1  H  N N 387 
TYR HE2  H  N N 388 
TYR HH   H  N N 389 
TYR HXT  H  N N 390 
VAL N    N  N N 391 
VAL CA   C  N S 392 
VAL C    C  N N 393 
VAL O    O  N N 394 
VAL CB   C  N N 395 
VAL CG1  C  N N 396 
VAL CG2  C  N N 397 
VAL OXT  O  N N 398 
VAL H    H  N N 399 
VAL H2   H  N N 400 
VAL HA   H  N N 401 
VAL HB   H  N N 402 
VAL HG11 H  N N 403 
VAL HG12 H  N N 404 
VAL HG13 H  N N 405 
VAL HG21 H  N N 406 
VAL HG22 H  N N 407 
VAL HG23 H  N N 408 
VAL HXT  H  N N 409 
ZN  ZN   ZN N N 410 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
GOL C1  O1   sing N N 129 
GOL C1  C2   sing N N 130 
GOL C1  H11  sing N N 131 
GOL C1  H12  sing N N 132 
GOL O1  HO1  sing N N 133 
GOL C2  O2   sing N N 134 
GOL C2  C3   sing N N 135 
GOL C2  H2   sing N N 136 
GOL O2  HO2  sing N N 137 
GOL C3  O3   sing N N 138 
GOL C3  H31  sing N N 139 
GOL C3  H32  sing N N 140 
GOL O3  HO3  sing N N 141 
HIS N   CA   sing N N 142 
HIS N   H    sing N N 143 
HIS N   H2   sing N N 144 
HIS CA  C    sing N N 145 
HIS CA  CB   sing N N 146 
HIS CA  HA   sing N N 147 
HIS C   O    doub N N 148 
HIS C   OXT  sing N N 149 
HIS CB  CG   sing N N 150 
HIS CB  HB2  sing N N 151 
HIS CB  HB3  sing N N 152 
HIS CG  ND1  sing Y N 153 
HIS CG  CD2  doub Y N 154 
HIS ND1 CE1  doub Y N 155 
HIS ND1 HD1  sing N N 156 
HIS CD2 NE2  sing Y N 157 
HIS CD2 HD2  sing N N 158 
HIS CE1 NE2  sing Y N 159 
HIS CE1 HE1  sing N N 160 
HIS NE2 HE2  sing N N 161 
HIS OXT HXT  sing N N 162 
HOH O   H1   sing N N 163 
HOH O   H2   sing N N 164 
ILE N   CA   sing N N 165 
ILE N   H    sing N N 166 
ILE N   H2   sing N N 167 
ILE CA  C    sing N N 168 
ILE CA  CB   sing N N 169 
ILE CA  HA   sing N N 170 
ILE C   O    doub N N 171 
ILE C   OXT  sing N N 172 
ILE CB  CG1  sing N N 173 
ILE CB  CG2  sing N N 174 
ILE CB  HB   sing N N 175 
ILE CG1 CD1  sing N N 176 
ILE CG1 HG12 sing N N 177 
ILE CG1 HG13 sing N N 178 
ILE CG2 HG21 sing N N 179 
ILE CG2 HG22 sing N N 180 
ILE CG2 HG23 sing N N 181 
ILE CD1 HD11 sing N N 182 
ILE CD1 HD12 sing N N 183 
ILE CD1 HD13 sing N N 184 
ILE OXT HXT  sing N N 185 
LEU N   CA   sing N N 186 
LEU N   H    sing N N 187 
LEU N   H2   sing N N 188 
LEU CA  C    sing N N 189 
LEU CA  CB   sing N N 190 
LEU CA  HA   sing N N 191 
LEU C   O    doub N N 192 
LEU C   OXT  sing N N 193 
LEU CB  CG   sing N N 194 
LEU CB  HB2  sing N N 195 
LEU CB  HB3  sing N N 196 
LEU CG  CD1  sing N N 197 
LEU CG  CD2  sing N N 198 
LEU CG  HG   sing N N 199 
LEU CD1 HD11 sing N N 200 
LEU CD1 HD12 sing N N 201 
LEU CD1 HD13 sing N N 202 
LEU CD2 HD21 sing N N 203 
LEU CD2 HD22 sing N N 204 
LEU CD2 HD23 sing N N 205 
LEU OXT HXT  sing N N 206 
LYS N   CA   sing N N 207 
LYS N   H    sing N N 208 
LYS N   H2   sing N N 209 
LYS CA  C    sing N N 210 
LYS CA  CB   sing N N 211 
LYS CA  HA   sing N N 212 
LYS C   O    doub N N 213 
LYS C   OXT  sing N N 214 
LYS CB  CG   sing N N 215 
LYS CB  HB2  sing N N 216 
LYS CB  HB3  sing N N 217 
LYS CG  CD   sing N N 218 
LYS CG  HG2  sing N N 219 
LYS CG  HG3  sing N N 220 
LYS CD  CE   sing N N 221 
LYS CD  HD2  sing N N 222 
LYS CD  HD3  sing N N 223 
LYS CE  NZ   sing N N 224 
LYS CE  HE2  sing N N 225 
LYS CE  HE3  sing N N 226 
LYS NZ  HZ1  sing N N 227 
LYS NZ  HZ2  sing N N 228 
LYS NZ  HZ3  sing N N 229 
LYS OXT HXT  sing N N 230 
MET N   CA   sing N N 231 
MET N   H    sing N N 232 
MET N   H2   sing N N 233 
MET CA  C    sing N N 234 
MET CA  CB   sing N N 235 
MET CA  HA   sing N N 236 
MET C   O    doub N N 237 
MET C   OXT  sing N N 238 
MET CB  CG   sing N N 239 
MET CB  HB2  sing N N 240 
MET CB  HB3  sing N N 241 
MET CG  SD   sing N N 242 
MET CG  HG2  sing N N 243 
MET CG  HG3  sing N N 244 
MET SD  CE   sing N N 245 
MET CE  HE1  sing N N 246 
MET CE  HE2  sing N N 247 
MET CE  HE3  sing N N 248 
MET OXT HXT  sing N N 249 
PHE N   CA   sing N N 250 
PHE N   H    sing N N 251 
PHE N   H2   sing N N 252 
PHE CA  C    sing N N 253 
PHE CA  CB   sing N N 254 
PHE CA  HA   sing N N 255 
PHE C   O    doub N N 256 
PHE C   OXT  sing N N 257 
PHE CB  CG   sing N N 258 
PHE CB  HB2  sing N N 259 
PHE CB  HB3  sing N N 260 
PHE CG  CD1  doub Y N 261 
PHE CG  CD2  sing Y N 262 
PHE CD1 CE1  sing Y N 263 
PHE CD1 HD1  sing N N 264 
PHE CD2 CE2  doub Y N 265 
PHE CD2 HD2  sing N N 266 
PHE CE1 CZ   doub Y N 267 
PHE CE1 HE1  sing N N 268 
PHE CE2 CZ   sing Y N 269 
PHE CE2 HE2  sing N N 270 
PHE CZ  HZ   sing N N 271 
PHE OXT HXT  sing N N 272 
PRO N   CA   sing N N 273 
PRO N   CD   sing N N 274 
PRO N   H    sing N N 275 
PRO CA  C    sing N N 276 
PRO CA  CB   sing N N 277 
PRO CA  HA   sing N N 278 
PRO C   O    doub N N 279 
PRO C   OXT  sing N N 280 
PRO CB  CG   sing N N 281 
PRO CB  HB2  sing N N 282 
PRO CB  HB3  sing N N 283 
PRO CG  CD   sing N N 284 
PRO CG  HG2  sing N N 285 
PRO CG  HG3  sing N N 286 
PRO CD  HD2  sing N N 287 
PRO CD  HD3  sing N N 288 
PRO OXT HXT  sing N N 289 
SER N   CA   sing N N 290 
SER N   H    sing N N 291 
SER N   H2   sing N N 292 
SER CA  C    sing N N 293 
SER CA  CB   sing N N 294 
SER CA  HA   sing N N 295 
SER C   O    doub N N 296 
SER C   OXT  sing N N 297 
SER CB  OG   sing N N 298 
SER CB  HB2  sing N N 299 
SER CB  HB3  sing N N 300 
SER OG  HG   sing N N 301 
SER OXT HXT  sing N N 302 
SO4 S   O1   doub N N 303 
SO4 S   O2   doub N N 304 
SO4 S   O3   sing N N 305 
SO4 S   O4   sing N N 306 
THR N   CA   sing N N 307 
THR N   H    sing N N 308 
THR N   H2   sing N N 309 
THR CA  C    sing N N 310 
THR CA  CB   sing N N 311 
THR CA  HA   sing N N 312 
THR C   O    doub N N 313 
THR C   OXT  sing N N 314 
THR CB  OG1  sing N N 315 
THR CB  CG2  sing N N 316 
THR CB  HB   sing N N 317 
THR OG1 HG1  sing N N 318 
THR CG2 HG21 sing N N 319 
THR CG2 HG22 sing N N 320 
THR CG2 HG23 sing N N 321 
THR OXT HXT  sing N N 322 
TRP N   CA   sing N N 323 
TRP N   H    sing N N 324 
TRP N   H2   sing N N 325 
TRP CA  C    sing N N 326 
TRP CA  CB   sing N N 327 
TRP CA  HA   sing N N 328 
TRP C   O    doub N N 329 
TRP C   OXT  sing N N 330 
TRP CB  CG   sing N N 331 
TRP CB  HB2  sing N N 332 
TRP CB  HB3  sing N N 333 
TRP CG  CD1  doub Y N 334 
TRP CG  CD2  sing Y N 335 
TRP CD1 NE1  sing Y N 336 
TRP CD1 HD1  sing N N 337 
TRP CD2 CE2  doub Y N 338 
TRP CD2 CE3  sing Y N 339 
TRP NE1 CE2  sing Y N 340 
TRP NE1 HE1  sing N N 341 
TRP CE2 CZ2  sing Y N 342 
TRP CE3 CZ3  doub Y N 343 
TRP CE3 HE3  sing N N 344 
TRP CZ2 CH2  doub Y N 345 
TRP CZ2 HZ2  sing N N 346 
TRP CZ3 CH2  sing Y N 347 
TRP CZ3 HZ3  sing N N 348 
TRP CH2 HH2  sing N N 349 
TRP OXT HXT  sing N N 350 
TYR N   CA   sing N N 351 
TYR N   H    sing N N 352 
TYR N   H2   sing N N 353 
TYR CA  C    sing N N 354 
TYR CA  CB   sing N N 355 
TYR CA  HA   sing N N 356 
TYR C   O    doub N N 357 
TYR C   OXT  sing N N 358 
TYR CB  CG   sing N N 359 
TYR CB  HB2  sing N N 360 
TYR CB  HB3  sing N N 361 
TYR CG  CD1  doub Y N 362 
TYR CG  CD2  sing Y N 363 
TYR CD1 CE1  sing Y N 364 
TYR CD1 HD1  sing N N 365 
TYR CD2 CE2  doub Y N 366 
TYR CD2 HD2  sing N N 367 
TYR CE1 CZ   doub Y N 368 
TYR CE1 HE1  sing N N 369 
TYR CE2 CZ   sing Y N 370 
TYR CE2 HE2  sing N N 371 
TYR CZ  OH   sing N N 372 
TYR OH  HH   sing N N 373 
TYR OXT HXT  sing N N 374 
VAL N   CA   sing N N 375 
VAL N   H    sing N N 376 
VAL N   H2   sing N N 377 
VAL CA  C    sing N N 378 
VAL CA  CB   sing N N 379 
VAL CA  HA   sing N N 380 
VAL C   O    doub N N 381 
VAL C   OXT  sing N N 382 
VAL CB  CG1  sing N N 383 
VAL CB  CG2  sing N N 384 
VAL CB  HB   sing N N 385 
VAL CG1 HG11 sing N N 386 
VAL CG1 HG12 sing N N 387 
VAL CG1 HG13 sing N N 388 
VAL CG2 HG21 sing N N 389 
VAL CG2 HG22 sing N N 390 
VAL CG2 HG23 sing N N 391 
VAL OXT HXT  sing N N 392 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                Spain 
_pdbx_audit_support.grant_number           P20_00149 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7D6H 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9F7Q 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012161 
_atom_sites.fract_transf_matrix[1][2]   0.007021 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.014042 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007485 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345  0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 24.64596 5.25405 ? ? 2.14387  29.76375 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . VAL A 1 3   ? 52.25900  -41.72400 75.52100 1.000 102.82812 ? 3   VAL A N    1 
ATOM   2    C  CA   . VAL A 1 3   ? 52.34800  -42.20200 74.14700 1.000 101.18318 ? 3   VAL A CA   1 
ATOM   3    C  C    . VAL A 1 3   ? 52.85000  -41.08500 73.24000 1.000 100.85946 ? 3   VAL A C    1 
ATOM   4    O  O    . VAL A 1 3   ? 52.76400  -39.90700 73.58500 1.000 101.31741 ? 3   VAL A O    1 
ATOM   5    C  CB   . VAL A 1 3   ? 50.98700  -42.73500 73.65400 1.000 97.66697  ? 3   VAL A CB   1 
ATOM   6    C  CG1  . VAL A 1 3   ? 50.06200  -41.58400 73.27800 1.000 98.28284  ? 3   VAL A CG1  1 
ATOM   7    C  CG2  . VAL A 1 3   ? 51.17900  -43.68000 72.47400 1.000 98.38285  ? 3   VAL A CG2  1 
ATOM   8    H  HA   . VAL A 1 3   ? 52.98200  -42.93500 74.11100 1.000 121.53000 ? 3   VAL A HA   1 
ATOM   9    H  HB   . VAL A 1 3   ? 50.56900  -43.23300 74.37400 1.000 117.31000 ? 3   VAL A HB   1 
ATOM   10   H  HG11 . VAL A 1 3   ? 49.14800  -41.90800 73.25200 1.000 118.05000 ? 3   VAL A HG11 1 
ATOM   11   H  HG12 . VAL A 1 3   ? 50.14500  -40.88200 73.94300 1.000 118.05000 ? 3   VAL A HG12 1 
ATOM   12   H  HG13 . VAL A 1 3   ? 50.31700  -41.24500 72.40600 1.000 118.05000 ? 3   VAL A HG13 1 
ATOM   13   H  HG21 . VAL A 1 3   ? 50.32800  -44.09300 72.25900 1.000 118.17000 ? 3   VAL A HG21 1 
ATOM   14   H  HG22 . VAL A 1 3   ? 51.50100  -43.17300 71.71200 1.000 118.17000 ? 3   VAL A HG22 1 
ATOM   15   H  HG23 . VAL A 1 3   ? 51.82600  -44.36100 72.71600 1.000 118.17000 ? 3   VAL A HG23 1 
ATOM   16   N  N    . ARG A 1 4   ? 53.38000  -41.46500 72.08100 1.000 97.93279  ? 4   ARG A N    1 
ATOM   17   C  CA   . ARG A 1 4   ? 53.79500  -40.48400 71.09000 1.000 94.08233  ? 4   ARG A CA   1 
ATOM   18   C  C    . ARG A 1 4   ? 52.56900  -39.84300 70.45100 1.000 87.77105  ? 4   ARG A C    1 
ATOM   19   O  O    . ARG A 1 4   ? 51.55100  -40.50400 70.22500 1.000 84.19694  ? 4   ARG A O    1 
ATOM   20   C  CB   . ARG A 1 4   ? 54.66400  -41.14600 70.02200 1.000 93.79019  ? 4   ARG A CB   1 
ATOM   21   C  CG   . ARG A 1 4   ? 55.76700  -40.25500 69.47200 1.000 99.95146  ? 4   ARG A CG   1 
ATOM   22   C  CD   . ARG A 1 4   ? 56.75400  -41.05000 68.62800 1.000 100.41730 ? 4   ARG A CD   1 
ATOM   23   N  NE   . ARG A 1 4   ? 56.08000  -41.94600 67.69500 1.000 103.44925 ? 4   ARG A NE   1 
ATOM   24   C  CZ   . ARG A 1 4   ? 56.19200  -41.89900 66.37200 1.000 103.78876 ? 4   ARG A CZ   1 
ATOM   25   N  NH1  . ARG A 1 4   ? 56.95300  -40.99800 65.77000 1.000 104.99154 ? 4   ARG A NH1  1 
ATOM   26   N  NH2  . ARG A 1 4   ? 55.52200  -42.77800 65.63400 1.000 100.39625 ? 4   ARG A NH2  1 
ATOM   27   H  H    . ARG A 1 4   ? 53.50900  -42.28300 71.84600 1.000 117.63000 ? 4   ARG A H    1 
ATOM   28   H  HA   . ARG A 1 4   ? 54.32200  -39.78800 71.51300 1.000 113.01000 ? 4   ARG A HA   1 
ATOM   29   H  HB2  . ARG A 1 4   ? 55.08500  -41.93000 70.40800 1.000 112.66000 ? 4   ARG A HB2  1 
ATOM   30   H  HB3  . ARG A 1 4   ? 54.09800  -41.40500 69.27900 1.000 112.66000 ? 4   ARG A HB3  1 
ATOM   31   H  HG2  . ARG A 1 4   ? 55.37400  -39.56500 68.91400 1.000 120.06000 ? 4   ARG A HG2  1 
ATOM   32   H  HG3  . ARG A 1 4   ? 56.25100  -39.85000 70.20900 1.000 120.06000 ? 4   ARG A HG3  1 
ATOM   33   H  HD2  . ARG A 1 4   ? 57.30300  -40.43500 68.11600 1.000 120.62000 ? 4   ARG A HD2  1 
ATOM   34   H  HD3  . ARG A 1 4   ? 57.31400  -41.58500 69.21200 1.000 120.62000 ? 4   ARG A HD3  1 
ATOM   35   H  HE   . ARG A 1 4   ? 55.56900  -42.55300 68.02700 1.000 124.25000 ? 4   ARG A HE   1 
ATOM   36   H  HH11 . ARG A 1 4   ? 57.39100  -40.42300 66.23600 1.000 126.10000 ? 4   ARG A HH11 1 
ATOM   37   H  HH12 . ARG A 1 4   ? 57.01000  -40.98700 64.91200 1.000 126.10000 ? 4   ARG A HH12 1 
ATOM   38   H  HH21 . ARG A 1 4   ? 55.02400  -43.36800 66.01400 1.000 120.59000 ? 4   ARG A HH21 1 
ATOM   39   H  HH22 . ARG A 1 4   ? 55.58600  -42.75800 64.77600 1.000 120.59000 ? 4   ARG A HH22 1 
ATOM   40   N  N    . THR A 1 5   ? 52.66600  -38.54800 70.15700 1.000 80.30700  ? 5   THR A N    1 
ATOM   41   C  CA   . THR A 1 5   ? 51.53300  -37.81900 69.60900 1.000 78.17516  ? 5   THR A CA   1 
ATOM   42   C  C    . THR A 1 5   ? 52.02600  -36.71200 68.69000 1.000 74.66158  ? 5   THR A C    1 
ATOM   43   O  O    . THR A 1 5   ? 53.17400  -36.26600 68.77600 1.000 74.83266  ? 5   THR A O    1 
ATOM   44   C  CB   . THR A 1 5   ? 50.65700  -37.21400 70.71500 1.000 78.10410  ? 5   THR A CB   1 
ATOM   45   O  OG1  . THR A 1 5   ? 51.45000  -36.34500 71.53400 1.000 79.04895  ? 5   THR A OG1  1 
ATOM   46   C  CG2  . THR A 1 5   ? 50.04600  -38.30400 71.58000 1.000 78.56731  ? 5   THR A CG2  1 
ATOM   47   H  H    . THR A 1 5   ? 53.37600  -38.07400 70.26700 1.000 96.48000  ? 5   THR A H    1 
ATOM   48   H  HA   . THR A 1 5   ? 51.00100  -38.43700 69.08400 1.000 93.92000  ? 5   THR A HA   1 
ATOM   49   H  HB   . THR A 1 5   ? 49.93400  -36.70900 70.31000 1.000 93.84000  ? 5   THR A HB   1 
ATOM   50   H  HG1  . THR A 1 5   ? 50.98200  -36.03000 72.15700 1.000 94.97000  ? 5   THR A HG1  1 
ATOM   51   H  HG21 . THR A 1 5   ? 49.36200  -37.92700 72.15500 1.000 94.40000  ? 5   THR A HG21 1 
ATOM   52   H  HG22 . THR A 1 5   ? 49.64400  -38.98700 71.02000 1.000 94.40000  ? 5   THR A HG22 1 
ATOM   53   H  HG23 . THR A 1 5   ? 50.73100  -38.71300 72.13200 1.000 94.40000  ? 5   THR A HG23 1 
ATOM   54   N  N    . ILE A 1 6   ? 51.13200  -36.27500 67.80200 1.000 72.23234  ? 6   ILE A N    1 
ATOM   55   C  CA   . ILE A 1 6   ? 51.34900  -35.10600 66.96100 1.000 72.06917  ? 6   ILE A CA   1 
ATOM   56   C  C    . ILE A 1 6   ? 50.10400  -34.23400 67.03500 1.000 66.58956  ? 6   ILE A C    1 
ATOM   57   O  O    . ILE A 1 6   ? 49.01100  -34.69300 67.37700 1.000 63.81028  ? 6   ILE A O    1 
ATOM   58   C  CB   . ILE A 1 6   ? 51.66300  -35.47300 65.49100 1.000 72.60871  ? 6   ILE A CB   1 
ATOM   59   C  CG1  . ILE A 1 6   ? 50.43400  -36.09700 64.82100 1.000 68.29766  ? 6   ILE A CG1  1 
ATOM   60   C  CG2  . ILE A 1 6   ? 52.85800  -36.40700 65.43400 1.000 71.47962  ? 6   ILE A CG2  1 
ATOM   61   C  CD1  . ILE A 1 6   ? 50.66500  -36.59400 63.40100 1.000 75.09321  ? 6   ILE A CD1  1 
ATOM   62   H  H    . ILE A 1 6   ? 50.37100  -36.65200 67.66700 1.000 86.79000  ? 6   ILE A H    1 
ATOM   63   H  HA   . ILE A 1 6   ? 52.10500  -34.60500 67.30400 1.000 86.60000  ? 6   ILE A HA   1 
ATOM   64   H  HB   . ILE A 1 6   ? 51.88500  -34.66300 65.00600 1.000 87.24000  ? 6   ILE A HB   1 
ATOM   65   H  HG12 . ILE A 1 6   ? 50.14600  -36.85500 65.35200 1.000 82.07000  ? 6   ILE A HG12 1 
ATOM   66   H  HG13 . ILE A 1 6   ? 49.73100  -35.43000 64.78600 1.000 82.07000  ? 6   ILE A HG13 1 
ATOM   67   H  HG21 . ILE A 1 6   ? 53.05500  -36.61100 64.50600 1.000 85.89000  ? 6   ILE A HG21 1 
ATOM   68   H  HG22 . ILE A 1 6   ? 53.62000  -35.97200 65.84600 1.000 85.89000  ? 6   ILE A HG22 1 
ATOM   69   H  HG23 . ILE A 1 6   ? 52.64300  -37.22300 65.91300 1.000 85.89000  ? 6   ILE A HG23 1 
ATOM   70   H  HD11 . ILE A 1 6   ? 49.82900  -36.93800 63.04800 1.000 90.23000  ? 6   ILE A HD11 1 
ATOM   71   H  HD12 . ILE A 1 6   ? 50.97600  -35.85600 62.85500 1.000 90.23000  ? 6   ILE A HD12 1 
ATOM   72   H  HD13 . ILE A 1 6   ? 51.33100  -37.29800 63.41700 1.000 90.23000  ? 6   ILE A HD13 1 
ATOM   73   N  N    . LYS A 1 7   ? 50.28400  -32.96100 66.70600 1.000 69.07934  ? 7   LYS A N    1 
ATOM   74   C  CA   . LYS A 1 7   ? 49.19200  -32.00100 66.65400 1.000 64.63143  ? 7   LYS A CA   1 
ATOM   75   C  C    . LYS A 1 7   ? 48.70400  -31.89600 65.21500 1.000 62.87596  ? 7   LYS A C    1 
ATOM   76   O  O    . LYS A 1 7   ? 49.49200  -31.60700 64.30800 1.000 65.93159  ? 7   LYS A O    1 
ATOM   77   C  CB   . LYS A 1 7   ? 49.64300  -30.63600 67.17600 1.000 68.06342  ? 7   LYS A CB   1 
ATOM   78   C  CG   . LYS A 1 7   ? 48.59000  -29.53600 67.07700 1.000 62.26799  ? 7   LYS A CG   1 
ATOM   79   C  CD   . LYS A 1 7   ? 49.20400  -28.15600 67.28200 1.000 66.59219  ? 7   LYS A CD   1 
ATOM   80   C  CE   . LYS A 1 7   ? 49.89400  -27.65500 66.01900 1.000 73.22457  ? 7   LYS A CE   1 
ATOM   81   N  NZ   . LYS A 1 7   ? 50.61800  -26.37000 66.24100 1.000 74.59315  ? 7   LYS A NZ   1 
ATOM   82   H  H    . LYS A 1 7   ? 51.04900  -32.62300 66.50400 1.000 83.01000  ? 7   LYS A H    1 
ATOM   83   H  HA   . LYS A 1 7   ? 48.45700  -32.30700 67.20900 1.000 77.67000  ? 7   LYS A HA   1 
ATOM   84   H  HB2  . LYS A 1 7   ? 49.88300  -30.72700 68.11100 1.000 81.79000  ? 7   LYS A HB2  1 
ATOM   85   H  HB3  . LYS A 1 7   ? 50.41400  -30.34900 66.66100 1.000 81.79000  ? 7   LYS A HB3  1 
ATOM   86   H  HG2  . LYS A 1 7   ? 48.18100  -29.56000 66.19800 1.000 74.84000  ? 7   LYS A HG2  1 
ATOM   87   H  HG3  . LYS A 1 7   ? 47.91600  -29.67400 67.76000 1.000 74.84000  ? 7   LYS A HG3  1 
ATOM   88   H  HD2  . LYS A 1 7   ? 48.50600  -27.52500 67.51800 1.000 80.03000  ? 7   LYS A HD2  1 
ATOM   89   H  HD3  . LYS A 1 7   ? 49.86400  -28.20100 67.99200 1.000 80.03000  ? 7   LYS A HD3  1 
ATOM   90   H  HE2  . LYS A 1 7   ? 50.53800  -28.31700 65.72400 1.000 87.98000  ? 7   LYS A HE2  1 
ATOM   91   H  HE3  . LYS A 1 7   ? 49.22700  -27.51000 65.32900 1.000 87.98000  ? 7   LYS A HE3  1 
ATOM   92   H  HZ1  . LYS A 1 7   ? 51.02000  -26.11400 65.49000 1.000 89.62000  ? 7   LYS A HZ1  1 
ATOM   93   H  HZ2  . LYS A 1 7   ? 50.04500  -25.73800 66.49300 1.000 89.62000  ? 7   LYS A HZ2  1 
ATOM   94   H  HZ3  . LYS A 1 7   ? 51.23200  -26.47300 66.87700 1.000 89.62000  ? 7   LYS A HZ3  1 
ATOM   95   N  N    . VAL A 1 8   ? 47.41200  -32.14400 65.00900 1.000 58.49649  ? 8   VAL A N    1 
ATOM   96   C  CA   . VAL A 1 8   ? 46.76600  -31.95100 63.72000 1.000 60.59937  ? 8   VAL A CA   1 
ATOM   97   C  C    . VAL A 1 8   ? 45.48900  -31.15400 63.94800 1.000 55.91986  ? 8   VAL A C    1 
ATOM   98   O  O    . VAL A 1 8   ? 45.01800  -30.99800 65.07500 1.000 54.00121  ? 8   VAL A O    1 
ATOM   99   C  CB   . VAL A 1 8   ? 46.45200  -33.28200 63.00300 1.000 57.34898  ? 8   VAL A CB   1 
ATOM   100  C  CG1  . VAL A 1 8   ? 47.68200  -34.17600 62.97100 1.000 61.37052  ? 8   VAL A CG1  1 
ATOM   101  C  CG2  . VAL A 1 8   ? 45.28300  -33.98900 63.67500 1.000 59.55977  ? 8   VAL A CG2  1 
ATOM   102  H  H    . VAL A 1 8   ? 46.87800  -32.43200 65.61900 1.000 70.31000  ? 8   VAL A H    1 
ATOM   103  H  HA   . VAL A 1 8   ? 47.35500  -31.43900 63.14400 1.000 72.83000  ? 8   VAL A HA   1 
ATOM   104  H  HB   . VAL A 1 8   ? 46.19800  -33.09100 62.08700 1.000 68.93000  ? 8   VAL A HB   1 
ATOM   105  H  HG11 . VAL A 1 8   ? 47.49000  -34.95800 62.43100 1.000 73.76000  ? 8   VAL A HG11 1 
ATOM   106  H  HG12 . VAL A 1 8   ? 48.42200  -33.68100 62.58600 1.000 73.76000  ? 8   VAL A HG12 1 
ATOM   107  H  HG13 . VAL A 1 8   ? 47.90000  -34.44500 63.87700 1.000 73.76000  ? 8   VAL A HG13 1 
ATOM   108  H  HG21 . VAL A 1 8   ? 45.28800  -34.92400 63.41500 1.000 71.58000  ? 8   VAL A HG21 1 
ATOM   109  H  HG22 . VAL A 1 8   ? 45.37900  -33.91300 64.63700 1.000 71.58000  ? 8   VAL A HG22 1 
ATOM   110  H  HG23 . VAL A 1 8   ? 44.45500  -33.57100 63.39100 1.000 71.58000  ? 8   VAL A HG23 1 
ATOM   111  N  N    . PHE A 1 9   ? 44.93000  -30.64900 62.85400 1.000 54.69340  ? 9   PHE A N    1 
ATOM   112  C  CA   . PHE A 1 9   ? 43.69200  -29.88600 62.88200 1.000 50.84031  ? 9   PHE A CA   1 
ATOM   113  C  C    . PHE A 1 9   ? 42.63300  -30.62600 62.08100 1.000 50.60870  ? 9   PHE A C    1 
ATOM   114  O  O    . PHE A 1 9   ? 42.90000  -31.07800 60.96200 1.000 55.38559  ? 9   PHE A O    1 
ATOM   115  C  CB   . PHE A 1 9   ? 43.89300  -28.48100 62.31000 1.000 51.51670  ? 9   PHE A CB   1 
ATOM   116  C  CG   . PHE A 1 9   ? 44.96700  -27.69300 63.00100 1.000 55.42243  ? 9   PHE A CG   1 
ATOM   117  C  CD1  . PHE A 1 9   ? 44.76700  -27.19300 64.27700 1.000 52.49840  ? 9   PHE A CD1  1 
ATOM   118  C  CD2  . PHE A 1 9   ? 46.17500  -27.45000 62.37300 1.000 55.20662  ? 9   PHE A CD2  1 
ATOM   119  C  CE1  . PHE A 1 9   ? 45.75400  -26.46700 64.91300 1.000 55.80406  ? 9   PHE A CE1  1 
ATOM   120  C  CE2  . PHE A 1 9   ? 47.16600  -26.72500 63.00400 1.000 59.30448  ? 9   PHE A CE2  1 
ATOM   121  C  CZ   . PHE A 1 9   ? 46.95500  -26.23200 64.27600 1.000 58.38595  ? 9   PHE A CZ   1 
ATOM   122  H  H    . PHE A 1 9   ? 45.26000  -30.73800 62.06400 1.000 65.74000  ? 9   PHE A H    1 
ATOM   123  H  HA   . PHE A 1 9   ? 43.38600  -29.80100 63.79800 1.000 61.12000  ? 9   PHE A HA   1 
ATOM   124  H  HB2  . PHE A 1 9   ? 44.13800  -28.55700 61.37400 1.000 61.94000  ? 9   PHE A HB2  1 
ATOM   125  H  HB3  . PHE A 1 9   ? 43.06300  -27.98700 62.39600 1.000 61.94000  ? 9   PHE A HB3  1 
ATOM   126  H  HD1  . PHE A 1 9   ? 43.95900  -27.34900 64.71000 1.000 63.11000  ? 9   PHE A HD1  1 
ATOM   127  H  HD2  . PHE A 1 9   ? 46.32200  -27.77900 61.51500 1.000 66.36000  ? 9   PHE A HD2  1 
ATOM   128  H  HE1  . PHE A 1 9   ? 45.60900  -26.13600 65.77000 1.000 67.08000  ? 9   PHE A HE1  1 
ATOM   129  H  HE2  . PHE A 1 9   ? 47.97500  -26.56900 62.57200 1.000 71.28000  ? 9   PHE A HE2  1 
ATOM   130  H  HZ   . PHE A 1 9   ? 47.62100  -25.74300 64.70300 1.000 70.18000  ? 9   PHE A HZ   1 
ATOM   131  N  N    . THR A 1 10  ? 41.44400  -30.75400 62.65400 1.000 47.77678  ? 10  THR A N    1 
ATOM   132  C  CA   . THR A 1 10  ? 40.29200  -31.28100 61.94100 1.000 49.43751  ? 10  THR A CA   1 
ATOM   133  C  C    . THR A 1 10  ? 39.42700  -30.12700 61.45200 1.000 49.55331  ? 10  THR A C    1 
ATOM   134  O  O    . THR A 1 10  ? 39.55800  -28.98500 61.90100 1.000 48.54003  ? 10  THR A O    1 
ATOM   135  C  CB   . THR A 1 10  ? 39.47100  -32.21800 62.82800 1.000 46.55558  ? 10  THR A CB   1 
ATOM   136  O  OG1  . THR A 1 10  ? 39.23100  -31.59900 64.09700 1.000 53.03267  ? 10  THR A OG1  1 
ATOM   137  C  CG2  . THR A 1 10  ? 40.20700  -33.53400 63.03300 1.000 51.41932  ? 10  THR A CG2  1 
ATOM   138  H  H    . THR A 1 10  ? 41.27800  -30.53800 63.47000 1.000 57.45000  ? 10  THR A H    1 
ATOM   139  H  HA   . THR A 1 10  ? 40.59100  -31.79800 61.17700 1.000 59.44000  ? 10  THR A HA   1 
ATOM   140  H  HB   . THR A 1 10  ? 38.62000  -32.40700 62.40200 1.000 55.98000  ? 10  THR A HB   1 
ATOM   141  H  HG1  . THR A 1 10  ? 38.77100  -32.10700 64.58200 1.000 63.75000  ? 10  THR A HG1  1 
ATOM   142  H  HG21 . THR A 1 10  ? 39.73300  -34.08400 63.67600 1.000 61.81000  ? 10  THR A HG21 1 
ATOM   143  H  HG22 . THR A 1 10  ? 40.26800  -34.01500 62.19300 1.000 61.81000  ? 10  THR A HG22 1 
ATOM   144  H  HG23 . THR A 1 10  ? 41.10300  -33.36500 63.36400 1.000 61.81000  ? 10  THR A HG23 1 
ATOM   145  N  N    . THR A 1 11  ? 38.53700  -30.43700 60.51700 1.000 47.72414  ? 11  THR A N    1 
ATOM   146  C  CA   . THR A 1 11  ? 37.72200  -29.40300 59.90000 1.000 45.62652  ? 11  THR A CA   1 
ATOM   147  C  C    . THR A 1 11  ? 36.61600  -30.06000 59.09200 1.000 47.50833  ? 11  THR A C    1 
ATOM   148  O  O    . THR A 1 11  ? 36.66300  -31.25700 58.79400 1.000 48.90323  ? 11  THR A O    1 
ATOM   149  C  CB   . THR A 1 11  ? 38.56300  -28.49100 58.99800 1.000 47.11354  ? 11  THR A CB   1 
ATOM   150  O  OG1  . THR A 1 11  ? 37.83700  -27.28900 58.71400 1.000 50.94295  ? 11  THR A OG1  1 
ATOM   151  C  CG2  . THR A 1 11  ? 38.90100  -29.19700 57.68800 1.000 48.32422  ? 11  THR A CG2  1 
ATOM   152  H  H    . THR A 1 11  ? 38.38900  -31.23300 60.22600 1.000 57.38000  ? 11  THR A H    1 
ATOM   153  H  HA   . THR A 1 11  ? 37.31100  -28.86700 60.59600 1.000 54.87000  ? 11  THR A HA   1 
ATOM   154  H  HB   . THR A 1 11  ? 39.39200  -28.26800 59.44900 1.000 56.65000  ? 11  THR A HB   1 
ATOM   155  H  HG1  . THR A 1 11  ? 37.66100  -26.88400 59.42900 1.000 61.24000  ? 11  THR A HG1  1 
ATOM   156  H  HG21 . THR A 1 11  ? 39.64200  -28.74900 57.25200 1.000 58.10000  ? 11  THR A HG21 1 
ATOM   157  H  HG22 . THR A 1 11  ? 39.14900  -30.11800 57.86300 1.000 58.10000  ? 11  THR A HG22 1 
ATOM   158  H  HG23 . THR A 1 11  ? 38.13300  -29.18400 57.09600 1.000 58.10000  ? 11  THR A HG23 1 
ATOM   159  N  N    . VAL A 1 12  ? 35.61400  -29.25400 58.75200 1.000 48.46897  ? 12  VAL A N    1 
ATOM   160  C  CA   . VAL A 1 12  ? 34.60900  -29.64100 57.77300 1.000 48.91376  ? 12  VAL A CA   1 
ATOM   161  C  C    . VAL A 1 12  ? 34.48800  -28.63700 56.63700 1.000 49.05325  ? 12  VAL A C    1 
ATOM   162  O  O    . VAL A 1 12  ? 33.92500  -28.98300 55.58500 1.000 50.82978  ? 12  VAL A O    1 
ATOM   163  C  CB   . VAL A 1 12  ? 33.23200  -29.85100 58.44000 1.000 46.64243  ? 12  VAL A CB   1 
ATOM   164  C  CG1  . VAL A 1 12  ? 33.28400  -31.02500 59.40100 1.000 53.29060  ? 12  VAL A CG1  1 
ATOM   165  C  CG2  . VAL A 1 12  ? 32.78600  -28.58800 59.15600 1.000 49.29802  ? 12  VAL A CG2  1 
ATOM   166  H  H    . VAL A 1 12  ? 35.49500  -28.46800 59.07900 1.000 58.28000  ? 12  VAL A H    1 
ATOM   167  H  HA   . VAL A 1 12  ? 34.87200  -30.48900 57.38300 1.000 58.81000  ? 12  VAL A HA   1 
ATOM   168  H  HB   . VAL A 1 12  ? 32.57800  -30.05100 57.75200 1.000 56.08000  ? 12  VAL A HB   1 
ATOM   169  H  HG11 . VAL A 1 12  ? 32.45300  -31.06100 59.90000 1.000 64.06000  ? 12  VAL A HG11 1 
ATOM   170  H  HG12 . VAL A 1 12  ? 33.40100  -31.84400 58.89400 1.000 64.06000  ? 12  VAL A HG12 1 
ATOM   171  H  HG13 . VAL A 1 12  ? 34.03000  -30.90300 60.00900 1.000 64.06000  ? 12  VAL A HG13 1 
ATOM   172  H  HG21 . VAL A 1 12  ? 31.92600  -28.75000 59.57400 1.000 59.27000  ? 12  VAL A HG21 1 
ATOM   173  H  HG22 . VAL A 1 12  ? 33.44400  -28.35800 59.83100 1.000 59.27000  ? 12  VAL A HG22 1 
ATOM   174  H  HG23 . VAL A 1 12  ? 32.71000  -27.86900 58.51000 1.000 59.27000  ? 12  VAL A HG23 1 
ATOM   175  N  N    . ASP A 1 13  ? 34.99500  -27.41400 56.80100 1.000 50.59028  ? 13  ASP A N    1 
ATOM   176  C  CA   . ASP A 1 13  ? 34.93700  -26.38400 55.77400 1.000 49.15063  ? 13  ASP A CA   1 
ATOM   177  C  C    . ASP A 1 13  ? 36.31200  -25.85000 55.39100 1.000 50.67976  ? 13  ASP A C    1 
ATOM   178  O  O    . ASP A 1 13  ? 36.39800  -24.95700 54.54000 1.000 51.27194  ? 13  ASP A O    1 
ATOM   179  C  CB   . ASP A 1 13  ? 34.05000  -25.22100 56.24500 1.000 54.18018  ? 13  ASP A CB   1 
ATOM   180  C  CG   . ASP A 1 13  ? 34.56300  -24.56900 57.51900 1.000 52.48524  ? 13  ASP A CG   1 
ATOM   181  O  OD1  . ASP A 1 13  ? 35.70600  -24.86400 57.92700 1.000 52.99583  ? 13  ASP A OD1  1 
ATOM   182  O  OD2  . ASP A 1 13  ? 33.81800  -23.76000 58.11400 1.000 56.52257  ? 13  ASP A OD2  1 
ATOM   183  H  H    . ASP A 1 13  ? 35.38700  -27.15300 57.52000 1.000 60.82000  ? 13  ASP A H    1 
ATOM   184  H  HA   . ASP A 1 13  ? 34.53500  -26.76100 54.97600 1.000 59.09000  ? 13  ASP A HA   1 
ATOM   185  H  HB2  . ASP A 1 13  ? 34.02200  -24.54400 55.55100 1.000 65.13000  ? 13  ASP A HB2  1 
ATOM   186  H  HB3  . ASP A 1 13  ? 33.15600  -25.55600 56.41800 1.000 65.13000  ? 13  ASP A HB3  1 
ATOM   187  N  N    . ASN A 1 14  ? 37.38000  -26.35800 56.00200 1.000 51.85359  ? 14  ASN A N    1 
ATOM   188  C  CA   . ASN A 1 14  ? 38.76000  -25.95400 55.75000 1.000 55.91986  ? 14  ASN A CA   1 
ATOM   189  C  C    . ASN A 1 14  ? 39.02600  -24.49000 56.07600 1.000 52.73264  ? 14  ASN A C    1 
ATOM   190  O  O    . ASN A 1 14  ? 40.06100  -23.94800 55.66800 1.000 56.07514  ? 14  ASN A O    1 
ATOM   191  C  CB   . ASN A 1 14  ? 39.17400  -26.23300 54.30100 1.000 51.98518  ? 14  ASN A CB   1 
ATOM   192  C  CG   . ASN A 1 14  ? 40.66600  -26.46400 54.16200 1.000 61.67318  ? 14  ASN A CG   1 
ATOM   193  O  OD1  . ASN A 1 14  ? 41.23200  -27.34100 54.81500 1.000 58.03591  ? 14  ASN A OD1  1 
ATOM   194  N  ND2  . ASN A 1 14  ? 41.31200  -25.67300 53.31200 1.000 66.71063  ? 14  ASN A ND2  1 
ATOM   195  H  H    . ASN A 1 14  ? 37.32500  -26.97300 56.60000 1.000 62.34000  ? 14  ASN A H    1 
ATOM   196  H  HA   . ASN A 1 14  ? 39.32400  -26.48400 56.33500 1.000 67.22000  ? 14  ASN A HA   1 
ATOM   197  H  HB2  . ASN A 1 14  ? 38.71600  -27.02900 53.98800 1.000 62.50000  ? 14  ASN A HB2  1 
ATOM   198  H  HB3  . ASN A 1 14  ? 38.93300  -25.47300 53.75000 1.000 62.50000  ? 14  ASN A HB3  1 
ATOM   199  H  HD21 . ASN A 1 14  ? 42.15900  -25.76600 53.19800 1.000 80.17000  ? 14  ASN A HD21 1 
ATOM   200  H  HD22 . ASN A 1 14  ? 40.88300  -25.07000 52.87500 1.000 80.17000  ? 14  ASN A HD22 1 
ATOM   201  N  N    . ILE A 1 15  ? 38.12200  -23.83300 56.79600 1.000 51.20351  ? 15  ILE A N    1 
ATOM   202  C  CA   . ILE A 1 15  ? 38.35000  -22.48900 57.32300 1.000 47.43990  ? 15  ILE A CA   1 
ATOM   203  C  C    . ILE A 1 15  ? 38.47100  -22.52300 58.84400 1.000 55.24873  ? 15  ILE A C    1 
ATOM   204  O  O    . ILE A 1 15  ? 39.48700  -22.10900 59.40500 1.000 51.52723  ? 15  ILE A O    1 
ATOM   205  C  CB   . ILE A 1 15  ? 37.23800  -21.51700 56.87100 1.000 51.17456  ? 15  ILE A CB   1 
ATOM   206  C  CG1  . ILE A 1 15  ? 37.14800  -21.47800 55.34100 1.000 54.90922  ? 15  ILE A CG1  1 
ATOM   207  C  CG2  . ILE A 1 15  ? 37.49500  -20.12100 57.42300 1.000 46.05289  ? 15  ILE A CG2  1 
ATOM   208  C  CD1  . ILE A 1 15  ? 35.92200  -20.74900 54.81000 1.000 52.51156  ? 15  ILE A CD1  1 
ATOM   209  H  H    . ILE A 1 15  ? 37.35000  -24.15200 56.99900 1.000 61.56000  ? 15  ILE A H    1 
ATOM   210  H  HA   . ILE A 1 15  ? 39.18800  -22.15500 56.96700 1.000 57.04000  ? 15  ILE A HA   1 
ATOM   211  H  HB   . ILE A 1 15  ? 36.39200  -21.83800 57.22000 1.000 61.52000  ? 15  ILE A HB   1 
ATOM   212  H  HG12 . ILE A 1 15  ? 37.93300  -21.02500 54.99500 1.000 66.00000  ? 15  ILE A HG12 1 
ATOM   213  H  HG13 . ILE A 1 15  ? 37.11700  -22.38900 55.00900 1.000 66.00000  ? 15  ILE A HG13 1 
ATOM   214  H  HG21 . ILE A 1 15  ? 36.86700  -19.50100 57.02000 1.000 54.70000  ? 15  ILE A HG21 1 
ATOM   215  H  HG22 . ILE A 1 15  ? 37.37300  -20.13500 58.38500 1.000 54.70000  ? 15  ILE A HG22 1 
ATOM   216  H  HG23 . ILE A 1 15  ? 38.40400  -19.85800 57.20800 1.000 54.70000  ? 15  ILE A HG23 1 
ATOM   217  H  HD11 . ILE A 1 15  ? 35.84500  -20.91400 53.85700 1.000 63.13000  ? 15  ILE A HD11 1 
ATOM   218  H  HD12 . ILE A 1 15  ? 35.13400  -21.08200 55.26800 1.000 63.13000  ? 15  ILE A HD12 1 
ATOM   219  H  HD13 . ILE A 1 15  ? 36.02300  -19.79900 54.97500 1.000 63.13000  ? 15  ILE A HD13 1 
ATOM   220  N  N    . ASN A 1 16  ? 37.44800  -23.03100 59.52600 1.000 49.80597  ? 16  ASN A N    1 
ATOM   221  C  CA   . ASN A 1 16  ? 37.48600  -23.18400 60.97300 1.000 52.95372  ? 16  ASN A CA   1 
ATOM   222  C  C    . ASN A 1 16  ? 38.21100  -24.47900 61.32200 1.000 49.46119  ? 16  ASN A C    1 
ATOM   223  O  O    . ASN A 1 16  ? 37.74100  -25.57100 60.98500 1.000 45.26332  ? 16  ASN A O    1 
ATOM   224  C  CB   . ASN A 1 16  ? 36.07000  -23.18400 61.54300 1.000 50.80609  ? 16  ASN A CB   1 
ATOM   225  C  CG   . ASN A 1 16  ? 35.36200  -21.85800 61.34300 1.000 54.06175  ? 16  ASN A CG   1 
ATOM   226  O  OD1  . ASN A 1 16  ? 34.27300  -21.80300 60.77300 1.000 66.22899  ? 16  ASN A OD1  1 
ATOM   227  N  ND2  . ASN A 1 16  ? 35.98100  -20.78000 61.81000 1.000 59.77296  ? 16  ASN A ND2  1 
ATOM   228  H  H    . ASN A 1 16  ? 36.71200  -23.29600 59.16800 1.000 59.88000  ? 16  ASN A H    1 
ATOM   229  H  HA   . ASN A 1 16  ? 37.97100  -22.44300 61.36800 1.000 63.66000  ? 16  ASN A HA   1 
ATOM   230  H  HB2  . ASN A 1 16  ? 35.55000  -23.87300 61.10000 1.000 61.08000  ? 16  ASN A HB2  1 
ATOM   231  H  HB3  . ASN A 1 16  ? 36.11100  -23.36200 62.49600 1.000 61.08000  ? 16  ASN A HB3  1 
ATOM   232  H  HD21 . ASN A 1 16  ? 36.74300  -20.85800 62.20200 1.000 71.84000  ? 16  ASN A HD21 1 
ATOM   233  H  HD22 . ASN A 1 16  ? 35.62000  -20.00500 61.72100 1.000 71.84000  ? 16  ASN A HD22 1 
ATOM   234  N  N    . LEU A 1 17  ? 39.35300  -24.35500 61.99200 1.000 46.31871  ? 17  LEU A N    1 
ATOM   235  C  CA   . LEU A 1 17  ? 40.16000  -25.49500 62.39800 1.000 50.21655  ? 17  LEU A CA   1 
ATOM   236  C  C    . LEU A 1 17  ? 39.88700  -25.84900 63.85600 1.000 53.45904  ? 17  LEU A C    1 
ATOM   237  O  O    . LEU A 1 17  ? 39.50100  -24.99900 64.66200 1.000 50.46658  ? 17  LEU A O    1 
ATOM   238  C  CB   . LEU A 1 17  ? 41.64900  -25.19700 62.21100 1.000 47.11091  ? 17  LEU A CB   1 
ATOM   239  C  CG   . LEU A 1 17  ? 42.05400  -24.58700 60.86900 1.000 52.78264  ? 17  LEU A CG   1 
ATOM   240  C  CD1  . LEU A 1 17  ? 43.54100  -24.26600 60.86600 1.000 54.42758  ? 17  LEU A CD1  1 
ATOM   241  C  CD2  . LEU A 1 17  ? 41.70200  -25.52100 59.72000 1.000 52.36154  ? 17  LEU A CD2  1 
ATOM   242  H  H    . LEU A 1 17  ? 39.68800  -23.59900 62.22900 1.000 55.70000  ? 17  LEU A H    1 
ATOM   243  H  HA   . LEU A 1 17  ? 39.92900  -26.26200 61.85100 1.000 60.37000  ? 17  LEU A HA   1 
ATOM   244  H  HB2  . LEU A 1 17  ? 41.92100  -24.57400 62.90200 1.000 56.65000  ? 17  LEU A HB2  1 
ATOM   245  H  HB3  . LEU A 1 17  ? 42.13700  -26.03100 62.30500 1.000 56.65000  ? 17  LEU A HB3  1 
ATOM   246  H  HG   . LEU A 1 17  ? 41.56400  -23.76100 60.73600 1.000 63.45000  ? 17  LEU A HG   1 
ATOM   247  H  HD11 . LEU A 1 17  ? 43.81600  -24.05300 59.96000 1.000 65.43000  ? 17  LEU A HD11 1 
ATOM   248  H  HD12 . LEU A 1 17  ? 43.70100  -23.50700 61.44800 1.000 65.43000  ? 17  LEU A HD12 1 
ATOM   249  H  HD13 . LEU A 1 17  ? 44.03100  -25.03900 61.18700 1.000 65.43000  ? 17  LEU A HD13 1 
ATOM   250  H  HD21 . LEU A 1 17  ? 42.00600  -25.12600 58.88800 1.000 62.95000  ? 17  LEU A HD21 1 
ATOM   251  H  HD22 . LEU A 1 17  ? 42.14000  -26.37500 59.86100 1.000 62.95000  ? 17  LEU A HD22 1 
ATOM   252  H  HD23 . LEU A 1 17  ? 40.74000  -25.64300 59.69600 1.000 62.95000  ? 17  LEU A HD23 1 
ATOM   253  N  N    . HIS A 1 18  ? 40.09900  -27.12200 64.18700 1.000 48.31106  ? 18  HIS A N    1 
ATOM   254  C  CA   . HIS A 1 18  ? 39.91600  -27.62600 65.54300 1.000 53.12742  ? 18  HIS A CA   1 
ATOM   255  C  C    . HIS A 1 18  ? 41.15100  -28.42300 65.93000 1.000 51.65356  ? 18  HIS A C    1 
ATOM   256  O  O    . HIS A 1 18  ? 41.43400  -29.46400 65.32700 1.000 49.37171  ? 18  HIS A O    1 
ATOM   257  C  CB   . HIS A 1 18  ? 38.65500  -28.48800 65.64400 1.000 52.26942  ? 18  HIS A CB   1 
ATOM   258  C  CG   . HIS A 1 18  ? 37.42200  -27.80800 65.13600 1.000 52.60104  ? 18  HIS A CG   1 
ATOM   259  N  ND1  . HIS A 1 18  ? 36.67500  -26.94500 65.90900 1.000 55.06186  ? 18  HIS A ND1  1 
ATOM   260  C  CD2  . HIS A 1 18  ? 36.80800  -27.86000 63.93000 1.000 53.61695  ? 18  HIS A CD2  1 
ATOM   261  C  CE1  . HIS A 1 18  ? 35.65300  -26.49600 65.20200 1.000 55.75669  ? 18  HIS A CE1  1 
ATOM   262  N  NE2  . HIS A 1 18  ? 35.71100  -27.03600 63.99800 1.000 53.06163  ? 18  HIS A NE2  1 
ATOM   263  H  H    . HIS A 1 18  ? 40.35500  -27.72400 63.63000 1.000 58.09000  ? 18  HIS A H    1 
ATOM   264  H  HA   . HIS A 1 18  ? 39.82600  -26.88400 66.16200 1.000 63.87000  ? 18  HIS A HA   1 
ATOM   265  H  HB2  . HIS A 1 18  ? 38.78600  -29.29400 65.12100 1.000 62.84000  ? 18  HIS A HB2  1 
ATOM   266  H  HB3  . HIS A 1 18  ? 38.50600  -28.71500 66.57500 1.000 62.84000  ? 18  HIS A HB3  1 
ATOM   267  H  HD2  . HIS A 1 18  ? 37.07900  -28.36000 63.19400 1.000 64.45000  ? 18  HIS A HD2  1 
ATOM   268  H  HE1  . HIS A 1 18  ? 35.00400  -25.90200 65.50100 1.000 67.02000  ? 18  HIS A HE1  1 
ATOM   269  H  HE2  . HIS A 1 18  ? 35.15200  -26.89400 63.35900 1.000 63.79000  ? 18  HIS A HE2  1 
ATOM   270  N  N    . THR A 1 19  ? 41.88300  -27.93500 66.92900 1.000 50.14549  ? 19  THR A N    1 
ATOM   271  C  CA   . THR A 1 19  ? 43.13300  -28.57300 67.31800 1.000 52.02203  ? 19  THR A CA   1 
ATOM   272  C  C    . THR A 1 19  ? 42.87700  -29.97800 67.85000 1.000 51.56671  ? 19  THR A C    1 
ATOM   273  O  O    . THR A 1 19  ? 41.87500  -30.23600 68.52200 1.000 53.42219  ? 19  THR A O    1 
ATOM   274  C  CB   . THR A 1 19  ? 43.85100  -27.73700 68.37800 1.000 54.65919  ? 19  THR A CB   1 
ATOM   275  O  OG1  . THR A 1 19  ? 43.86400  -26.36000 67.97900 1.000 54.92237  ? 19  THR A OG1  1 
ATOM   276  C  CG2  . THR A 1 19  ? 45.28200  -28.22500 68.56000 1.000 51.32984  ? 19  THR A CG2  1 
ATOM   277  H  H    . THR A 1 19  ? 41.67800  -27.24100 67.39400 1.000 60.29000  ? 19  THR A H    1 
ATOM   278  H  HA   . THR A 1 19  ? 43.70900  -28.64000 66.54100 1.000 62.54000  ? 19  THR A HA   1 
ATOM   279  H  HB   . THR A 1 19  ? 43.38800  -27.82100 69.22600 1.000 65.70000  ? 19  THR A HB   1 
ATOM   280  H  HG1  . THR A 1 19  ? 44.29200  -26.27300 67.26200 1.000 66.02000  ? 19  THR A HG1  1 
ATOM   281  H  HG21 . THR A 1 19  ? 45.75100  -27.65100 69.18500 1.000 61.71000  ? 19  THR A HG21 1 
ATOM   282  H  HG22 . THR A 1 19  ? 45.28200  -29.13200 68.90400 1.000 61.71000  ? 19  THR A HG22 1 
ATOM   283  H  HG23 . THR A 1 19  ? 45.74800  -28.21100 67.70900 1.000 61.71000  ? 19  THR A HG23 1 
ATOM   284  N  N    . GLN A 1 20  ? 43.79700  -30.88900 67.54400 1.000 52.26416  ? 20  GLN A N    1 
ATOM   285  C  CA   . GLN A 1 20  ? 43.69200  -32.27800 67.95900 1.000 55.30400  ? 20  GLN A CA   1 
ATOM   286  C  C    . GLN A 1 20  ? 45.07900  -32.82000 68.26300 1.000 57.22528  ? 20  GLN A C    1 
ATOM   287  O  O    . GLN A 1 20  ? 46.02900  -32.56500 67.51700 1.000 60.38882  ? 20  GLN A O    1 
ATOM   288  C  CB   . GLN A 1 20  ? 43.03700  -33.14700 66.87400 1.000 56.05146  ? 20  GLN A CB   1 
ATOM   289  C  CG   . GLN A 1 20  ? 41.66200  -32.67900 66.41700 1.000 55.60667  ? 20  GLN A CG   1 
ATOM   290  C  CD   . GLN A 1 20  ? 40.61200  -32.78200 67.50600 1.000 55.64878  ? 20  GLN A CD   1 
ATOM   291  O  OE1  . GLN A 1 20  ? 40.82700  -33.42500 68.53400 1.000 53.86172  ? 20  GLN A OE1  1 
ATOM   292  N  NE2  . GLN A 1 20  ? 39.46500  -32.15100 67.28200 1.000 51.15087  ? 20  GLN A NE2  1 
ATOM   293  H  H    . GLN A 1 20  ? 44.50600  -30.72000 67.08600 1.000 62.83000  ? 20  GLN A H    1 
ATOM   294  H  HA   . GLN A 1 20  ? 43.15200  -32.32900 68.76300 1.000 66.48000  ? 20  GLN A HA   1 
ATOM   295  H  HB2  . GLN A 1 20  ? 43.61500  -33.15200 66.09500 1.000 67.37000  ? 20  GLN A HB2  1 
ATOM   296  H  HB3  . GLN A 1 20  ? 42.93700  -34.04700 67.22000 1.000 67.37000  ? 20  GLN A HB3  1 
ATOM   297  H  HG2  . GLN A 1 20  ? 41.71900  -31.75000 66.14400 1.000 66.84000  ? 20  GLN A HG2  1 
ATOM   298  H  HG3  . GLN A 1 20  ? 41.37400  -33.22800 65.67100 1.000 66.84000  ? 20  GLN A HG3  1 
ATOM   299  H  HE21 . GLN A 1 20  ? 39.35000  -31.71500 66.54900 1.000 61.49000  ? 20  GLN A HE21 1 
ATOM   300  H  HE22 . GLN A 1 20  ? 38.83700  -32.17900 67.86900 1.000 61.49000  ? 20  GLN A HE22 1 
ATOM   301  N  N    . VAL A 1 21  ? 45.17800  -33.58100 69.35700 1.000 57.69113  ? 21  VAL A N    1 
ATOM   302  C  CA   . VAL A 1 21  ? 46.41600  -34.32600 69.71400 1.000 65.21571  ? 21  VAL A CA   1 
ATOM   303  C  C    . VAL A 1 21  ? 46.06600  -35.78500 69.42300 1.000 67.28965  ? 21  VAL A C    1 
ATOM   304  O  O    . VAL A 1 21  ? 45.12200  -36.28100 70.04900 1.000 67.15805  ? 21  VAL A O    1 
ATOM   305  C  CB   . VAL A 1 21  ? 46.88300  -34.06500 71.15700 1.000 72.09022  ? 21  VAL A CB   1 
ATOM   306  C  CG1  . VAL A 1 21  ? 47.21700  -32.59800 71.34900 1.000 71.51384  ? 21  VAL A CG1  1 
ATOM   307  C  CG2  . VAL A 1 21  ? 45.89500  -34.52000 72.21800 1.000 80.16224  ? 21  VAL A CG2  1 
ATOM   308  H  H    . VAL A 1 21  ? 44.49600  -33.70500 69.94900 1.000 69.35000  ? 21  VAL A H    1 
ATOM   309  H  HA   . VAL A 1 21  ? 47.12800  -34.05800 69.11400 1.000 78.37000  ? 21  VAL A HA   1 
ATOM   310  H  HB   . VAL A 1 21  ? 47.71600  -34.57900 71.28800 1.000 86.62000  ? 21  VAL A HB   1 
ATOM   311  H  HG11 . VAL A 1 21  ? 47.93200  -32.51000 72.00100 1.000 85.93000  ? 21  VAL A HG11 1 
ATOM   312  H  HG12 . VAL A 1 21  ? 47.50200  -32.21800 70.50000 1.000 85.93000  ? 21  VAL A HG12 1 
ATOM   313  H  HG13 . VAL A 1 21  ? 46.42800  -32.12600 71.66600 1.000 85.93000  ? 21  VAL A HG13 1 
ATOM   314  H  HG21 . VAL A 1 21  ? 46.03500  -34.00300 73.02900 1.000 96.31000  ? 21  VAL A HG21 1 
ATOM   315  H  HG22 . VAL A 1 21  ? 44.98600  -34.38300 71.90300 1.000 96.31000  ? 21  VAL A HG22 1 
ATOM   316  H  HG23 . VAL A 1 21  ? 46.03500  -35.46300 72.41000 1.000 96.31000  ? 21  VAL A HG23 1 
ATOM   317  N  N    . VAL A 1 22  ? 46.75800  -36.43800 68.49300 1.000 63.89713  ? 22  VAL A N    1 
ATOM   318  C  CA   . VAL A 1 22  ? 46.42800  -37.77300 68.01200 1.000 69.79258  ? 22  VAL A CA   1 
ATOM   319  C  C    . VAL A 1 22  ? 47.46600  -38.76200 68.51600 1.000 71.38751  ? 22  VAL A C    1 
ATOM   320  O  O    . VAL A 1 22  ? 48.66500  -38.46200 68.55300 1.000 72.98243  ? 22  VAL A O    1 
ATOM   321  C  CB   . VAL A 1 22  ? 46.33800  -37.82700 66.47400 1.000 66.57114  ? 22  VAL A CB   1 
ATOM   322  C  CG1  . VAL A 1 22  ? 45.11200  -37.09000 65.99800 1.000 65.03411  ? 22  VAL A CG1  1 
ATOM   323  C  CG2  . VAL A 1 22  ? 47.58900  -37.25300 65.83900 1.000 65.33678  ? 22  VAL A CG2  1 
ATOM   324  H  H    . VAL A 1 22  ? 47.46400  -36.10600 68.13100 1.000 76.79000  ? 22  VAL A H    1 
ATOM   325  H  HA   . VAL A 1 22  ? 45.56500  -38.02000 68.38000 1.000 83.86000  ? 22  VAL A HA   1 
ATOM   326  H  HB   . VAL A 1 22  ? 46.26600  -38.75400 66.19700 1.000 80.00000  ? 22  VAL A HB   1 
ATOM   327  H  HG11 . VAL A 1 22  ? 45.06400  -37.14800 65.03100 1.000 78.15000  ? 22  VAL A HG11 1 
ATOM   328  H  HG12 . VAL A 1 22  ? 44.32600  -37.49800 66.39300 1.000 78.15000  ? 22  VAL A HG12 1 
ATOM   329  H  HG13 . VAL A 1 22  ? 45.17600  -36.16200 66.27100 1.000 78.15000  ? 22  VAL A HG13 1 
ATOM   330  H  HG21 . VAL A 1 22  ? 47.53400  -37.36300 64.87600 1.000 78.52000  ? 22  VAL A HG21 1 
ATOM   331  H  HG22 . VAL A 1 22  ? 47.65000  -36.31000 66.06000 1.000 78.52000  ? 22  VAL A HG22 1 
ATOM   332  H  HG23 . VAL A 1 22  ? 48.36300  -37.72500 66.18200 1.000 78.52000  ? 22  VAL A HG23 1 
ATOM   333  N  N    . ASP A 1 23  ? 46.99500  -39.94200 68.90200 1.000 76.07228  ? 23  ASP A N    1 
ATOM   334  C  CA   . ASP A 1 23  ? 47.86600  -41.05400 69.25200 1.000 75.82488  ? 23  ASP A CA   1 
ATOM   335  C  C    . ASP A 1 23  ? 48.42800  -41.66400 67.97400 1.000 79.72008  ? 23  ASP A C    1 
ATOM   336  O  O    . ASP A 1 23  ? 47.67000  -42.16600 67.13600 1.000 81.32817  ? 23  ASP A O    1 
ATOM   337  C  CB   . ASP A 1 23  ? 47.08200  -42.08800 70.05500 1.000 80.29647  ? 23  ASP A CB   1 
ATOM   338  C  CG   . ASP A 1 23  ? 47.97000  -43.13300 70.69200 1.000 83.89164  ? 23  ASP A CG   1 
ATOM   339  O  OD1  . ASP A 1 23  ? 48.98000  -43.52400 70.06900 1.000 87.31573  ? 23  ASP A OD1  1 
ATOM   340  O  OD2  . ASP A 1 23  ? 47.65100  -43.57100 71.81700 1.000 84.48645  ? 23  ASP A OD2  1 
ATOM   341  H  H    . ASP A 1 23  ? 46.15700  -40.12700 68.96900 1.000 91.40000  ? 23  ASP A H    1 
ATOM   342  H  HA   . ASP A 1 23  ? 48.60800  -40.74400 69.79600 1.000 91.10000  ? 23  ASP A HA   1 
ATOM   343  H  HB2  . ASP A 1 23  ? 46.59700  -41.63600 70.76300 1.000 96.47000  ? 23  ASP A HB2  1 
ATOM   344  H  HB3  . ASP A 1 23  ? 46.46100  -42.54200 69.46400 1.000 96.47000  ? 23  ASP A HB3  1 
ATOM   345  N  N    . MET A 1 24  ? 49.75400  -41.61900 67.81800 1.000 79.98591  ? 24  MET A N    1 
ATOM   346  C  CA   . MET A 1 24  ? 50.37200  -42.14800 66.60800 1.000 81.62031  ? 24  MET A CA   1 
ATOM   347  C  C    . MET A 1 24  ? 50.19300  -43.65400 66.47100 1.000 80.44122  ? 24  MET A C    1 
ATOM   348  O  O    . MET A 1 24  ? 50.40700  -44.19300 65.38000 1.000 86.53669  ? 24  MET A O    1 
ATOM   349  C  CB   . MET A 1 24  ? 51.86600  -41.81800 66.57700 1.000 86.07348  ? 24  MET A CB   1 
ATOM   350  C  CG   . MET A 1 24  ? 52.21100  -40.40000 67.00800 1.000 83.86269  ? 24  MET A CG   1 
ATOM   351  S  SD   . MET A 1 24  ? 53.63800  -39.66300 66.17000 1.000 97.38536  ? 24  MET A SD   1 
ATOM   352  C  CE   . MET A 1 24  ? 53.32200  -40.00400 64.43700 1.000 88.42639  ? 24  MET A CE   1 
ATOM   353  H  H    . MET A 1 24  ? 50.30600  -41.29200 68.39100 1.000 96.10000  ? 24  MET A H    1 
ATOM   354  H  HA   . MET A 1 24  ? 49.95200  -41.70900 65.85100 1.000 98.06000  ? 24  MET A HA   1 
ATOM   355  H  HB2  . MET A 1 24  ? 52.32900  -42.42600 67.17500 1.000 103.40000 ? 24  MET A HB2  1 
ATOM   356  H  HB3  . MET A 1 24  ? 52.18900  -41.93500 65.67000 1.000 103.40000 ? 24  MET A HB3  1 
ATOM   357  H  HG2  . MET A 1 24  ? 51.44500  -39.83200 66.83000 1.000 100.75000 ? 24  MET A HG2  1 
ATOM   358  H  HG3  . MET A 1 24  ? 52.40500  -40.40800 67.95800 1.000 100.75000 ? 24  MET A HG3  1 
ATOM   359  H  HE1  . MET A 1 24  ? 54.02900  -39.61000 63.90300 1.000 106.23000 ? 24  MET A HE1  1 
ATOM   360  H  HE2  . MET A 1 24  ? 53.30200  -40.96500 64.30300 1.000 106.23000 ? 24  MET A HE2  1 
ATOM   361  H  HE3  . MET A 1 24  ? 52.46700  -39.61800 64.19000 1.000 106.23000 ? 24  MET A HE3  1 
ATOM   362  N  N    . SER A 1 25  ? 49.81700  -44.34500 67.54400 1.000 78.32255  ? 25  SER A N    1 
ATOM   363  C  CA   . SER A 1 25  ? 49.62300  -45.78700 67.50600 1.000 83.34684  ? 25  SER A CA   1 
ATOM   364  C  C    . SER A 1 25  ? 48.19100  -46.18500 67.16500 1.000 82.59675  ? 25  SER A C    1 
ATOM   365  O  O    . SER A 1 25  ? 47.87100  -47.37800 67.19400 1.000 82.38356  ? 25  SER A O    1 
ATOM   366  C  CB   . SER A 1 25  ? 50.02100  -46.40800 68.84800 1.000 82.19670  ? 25  SER A CB   1 
ATOM   367  O  OG   . SER A 1 25  ? 49.02600  -46.17800 69.83100 1.000 78.23043  ? 25  SER A OG   1 
ATOM   368  H  H    . SER A 1 25  ? 49.66600  -43.99400 68.31400 1.000 94.10000  ? 25  SER A H    1 
ATOM   369  H  HA   . SER A 1 25  ? 50.20300  -46.15300 66.82100 1.000 100.13000 ? 25  SER A HA   1 
ATOM   370  H  HB2  . SER A 1 25  ? 50.13400  -47.36400 68.73200 1.000 98.75000  ? 25  SER A HB2  1 
ATOM   371  H  HB3  . SER A 1 25  ? 50.85400  -46.00900 69.14500 1.000 98.75000  ? 25  SER A HB3  1 
ATOM   372  H  HG   . SER A 1 25  ? 48.96600  -45.35600 69.99200 1.000 93.99000  ? 25  SER A HG   1 
ATOM   373  N  N    . MET A 1 26  ? 47.32900  -45.22200 66.84700 1.000 81.15710  ? 26  MET A N    1 
ATOM   374  C  CA   . MET A 1 26  ? 45.95000  -45.48400 66.46700 1.000 81.53083  ? 26  MET A CA   1 
ATOM   375  C  C    . MET A 1 26  ? 45.67100  -44.86600 65.10500 1.000 77.74616  ? 26  MET A C    1 
ATOM   376  O  O    . MET A 1 26  ? 46.25500  -43.84200 64.74000 1.000 78.73049  ? 26  MET A O    1 
ATOM   377  C  CB   . MET A 1 26  ? 44.96600  -44.91200 67.49300 1.000 83.44422  ? 26  MET A CB   1 
ATOM   378  C  CG   . MET A 1 26  ? 44.58500  -45.87400 68.60100 1.000 86.56564  ? 26  MET A CG   1 
ATOM   379  S  SD   . MET A 1 26  ? 44.19100  -45.01500 70.13600 1.000 86.29982  ? 26  MET A SD   1 
ATOM   380  C  CE   . MET A 1 26  ? 42.40200  -45.06400 70.10200 1.000 84.50487  ? 26  MET A CE   1 
ATOM   381  H  H    . MET A 1 26  ? 47.52900  -44.38500 66.84600 1.000 97.50000  ? 26  MET A H    1 
ATOM   382  H  HA   . MET A 1 26  ? 45.81100  -46.44300 66.42300 1.000 97.95000  ? 26  MET A HA   1 
ATOM   383  H  HB2  . MET A 1 26  ? 45.36900  -44.13300 67.90700 1.000 100.24000 ? 26  MET A HB2  1 
ATOM   384  H  HB3  . MET A 1 26  ? 44.15100  -44.65800 67.03100 1.000 100.24000 ? 26  MET A HB3  1 
ATOM   385  H  HG2  . MET A 1 26  ? 43.80400  -46.38100 68.32800 1.000 103.99000 ? 26  MET A HG2  1 
ATOM   386  H  HG3  . MET A 1 26  ? 45.32700  -46.47500 68.77100 1.000 103.99000 ? 26  MET A HG3  1 
ATOM   387  H  HE1  . MET A 1 26  ? 42.05800  -44.62000 70.89300 1.000 101.52000 ? 26  MET A HE1  1 
ATOM   388  H  HE2  . MET A 1 26  ? 42.08800  -44.61000 69.30400 1.000 101.52000 ? 26  MET A HE2  1 
ATOM   389  H  HE3  . MET A 1 26  ? 42.11100  -45.99000 70.09000 1.000 101.52000 ? 26  MET A HE3  1 
ATOM   390  N  N    . THR A 1 27  ? 44.77100  -45.49400 64.35700 1.000 73.94571  ? 27  THR A N    1 
ATOM   391  C  CA   . THR A 1 27  ? 44.37300  -44.94300 63.07200 1.000 74.81160  ? 27  THR A CA   1 
ATOM   392  C  C    . THR A 1 27  ? 43.53400  -43.68800 63.28100 1.000 69.38463  ? 27  THR A C    1 
ATOM   393  O  O    . THR A 1 27  ? 42.89500  -43.50700 64.32000 1.000 69.46096  ? 27  THR A O    1 
ATOM   394  C  CB   . THR A 1 27  ? 43.57700  -45.96700 62.26200 1.000 74.80897  ? 27  THR A CB   1 
ATOM   395  O  OG1  . THR A 1 27  ? 42.32600  -46.22800 62.91000 1.000 74.13257  ? 27  THR A OG1  1 
ATOM   396  C  CG2  . THR A 1 27  ? 44.35900  -47.26600 62.12100 1.000 74.42208  ? 27  THR A CG2  1 
ATOM   397  H  H    . THR A 1 27  ? 44.38200  -46.23100 64.56800 1.000 88.85000  ? 27  THR A H    1 
ATOM   398  H  HA   . THR A 1 27  ? 45.16400  -44.71200 62.56000 1.000 89.89000  ? 27  THR A HA   1 
ATOM   399  H  HB   . THR A 1 27  ? 43.41200  -45.61600 61.37300 1.000 89.89000  ? 27  THR A HB   1 
ATOM   400  H  HG1  . THR A 1 27  ? 41.88600  -46.79100 62.46900 1.000 89.07000  ? 27  THR A HG1  1 
ATOM   401  H  HG21 . THR A 1 27  ? 43.84700  -47.90700 61.60300 1.000 89.42000  ? 27  THR A HG21 1 
ATOM   402  H  HG22 . THR A 1 27  ? 45.20200  -47.09900 61.67100 1.000 89.42000  ? 27  THR A HG22 1 
ATOM   403  H  HG23 . THR A 1 27  ? 44.53800  -47.64200 62.99700 1.000 89.42000  ? 27  THR A HG23 1 
ATOM   404  N  N    . TYR A 1 28  ? 43.54900  -42.81000 62.27800 1.000 70.46898  ? 28  TYR A N    1 
ATOM   405  C  CA   . TYR A 1 28  ? 42.68100  -41.64000 62.32400 1.000 67.43440  ? 28  TYR A CA   1 
ATOM   406  C  C    . TYR A 1 28  ? 41.22500  -42.04400 62.50800 1.000 64.68144  ? 28  TYR A C    1 
ATOM   407  O  O    . TYR A 1 28  ? 40.45700  -41.32400 63.15600 1.000 65.92106  ? 28  TYR A O    1 
ATOM   408  C  CB   . TYR A 1 28  ? 42.84900  -40.81400 61.04900 1.000 63.51814  ? 28  TYR A CB   1 
ATOM   409  C  CG   . TYR A 1 28  ? 44.13800  -40.02700 61.00900 1.000 65.38679  ? 28  TYR A CG   1 
ATOM   410  C  CD1  . TYR A 1 28  ? 44.31700  -38.91200 61.81800 1.000 64.87094  ? 28  TYR A CD1  1 
ATOM   411  C  CD2  . TYR A 1 28  ? 45.17800  -40.40200 60.17000 1.000 66.05266  ? 28  TYR A CD2  1 
ATOM   412  C  CE1  . TYR A 1 28  ? 45.49300  -38.19100 61.78800 1.000 63.54446  ? 28  TYR A CE1  1 
ATOM   413  C  CE2  . TYR A 1 28  ? 46.35900  -39.68700 60.13400 1.000 66.41849  ? 28  TYR A CE2  1 
ATOM   414  C  CZ   . TYR A 1 28  ? 46.51000  -38.58300 60.94600 1.000 66.14740  ? 28  TYR A CZ   1 
ATOM   415  O  OH   . TYR A 1 28  ? 47.68200  -37.86400 60.91700 1.000 66.34480  ? 28  TYR A OH   1 
ATOM   416  H  H    . TYR A 1 28  ? 44.04200  -42.86800 61.57500 1.000 84.68000  ? 28  TYR A H    1 
ATOM   417  H  HA   . TYR A 1 28  ? 42.93700  -41.08300 63.07500 1.000 81.03000  ? 28  TYR A HA   1 
ATOM   418  H  HB2  . TYR A 1 28  ? 42.84100  -41.41200 60.28500 1.000 76.33000  ? 28  TYR A HB2  1 
ATOM   419  H  HB3  . TYR A 1 28  ? 42.11300  -40.18400 60.98500 1.000 76.33000  ? 28  TYR A HB3  1 
ATOM   420  H  HD1  . TYR A 1 28  ? 43.63300  -38.64700 62.38900 1.000 77.96000  ? 28  TYR A HD1  1 
ATOM   421  H  HD2  . TYR A 1 28  ? 45.07800  -41.14700 59.62300 1.000 79.38000  ? 28  TYR A HD2  1 
ATOM   422  H  HE1  . TYR A 1 28  ? 45.59800  -37.44500 62.33300 1.000 76.37000  ? 28  TYR A HE1  1 
ATOM   423  H  HE2  . TYR A 1 28  ? 47.04700  -39.94800 59.56500 1.000 79.81000  ? 28  TYR A HE2  1 
ATOM   424  H  HH   . TYR A 1 28  ? 48.28300  -38.31000 60.53500 1.000 79.73000  ? 28  TYR A HH   1 
ATOM   425  N  N    . GLY A 1 29  ? 40.83100  -43.19500 61.96100 1.000 63.63658  ? 29  GLY A N    1 
ATOM   426  C  CA   . GLY A 1 29  ? 39.45500  -43.63700 62.10400 1.000 64.01557  ? 29  GLY A CA   1 
ATOM   427  C  C    . GLY A 1 29  ? 39.09700  -43.98300 63.53500 1.000 67.21595  ? 29  GLY A C    1 
ATOM   428  O  O    . GLY A 1 29  ? 37.98100  -43.71500 63.98800 1.000 67.58442  ? 29  GLY A O    1 
ATOM   429  H  H    . GLY A 1 29  ? 41.33600  -43.72700 61.51100 1.000 76.48000  ? 29  GLY A H    1 
ATOM   430  H  HA2  . GLY A 1 29  ? 38.86000  -42.93200 61.80300 1.000 76.93000  ? 29  GLY A HA2  1 
ATOM   431  H  HA3  . GLY A 1 29  ? 39.31300  -44.42400 61.55500 1.000 76.93000  ? 29  GLY A HA3  1 
ATOM   432  N  N    . GLN A 1 30  ? 40.03600  -44.58400 64.26800 1.000 64.96305  ? 30  GLN A N    1 
ATOM   433  C  CA   . GLN A 1 30  ? 39.77900  -44.93100 65.66000 1.000 69.97155  ? 30  GLN A CA   1 
ATOM   434  C  C    . GLN A 1 30  ? 39.61400  -43.70000 66.54200 1.000 67.75812  ? 30  GLN A C    1 
ATOM   435  O  O    . GLN A 1 30  ? 39.04600  -43.81000 67.63300 1.000 69.47149  ? 30  GLN A O    1 
ATOM   436  C  CB   . GLN A 1 30  ? 40.91200  -45.80400 66.20200 1.000 65.49733  ? 30  GLN A CB   1 
ATOM   437  H  H    . GLN A 1 30  ? 40.81900  -44.79900 63.98500 1.000 78.07000  ? 30  GLN A H    1 
ATOM   438  H  HA   . GLN A 1 30  ? 38.95600  -45.44200 65.70400 1.000 84.08000  ? 30  GLN A HA   1 
ATOM   439  N  N    . GLN A 1 31  ? 40.08400  -42.53700 66.09500 1.000 66.63167  ? 31  GLN A N    1 
ATOM   440  C  CA   . GLN A 1 31  ? 40.06600  -41.31800 66.89600 1.000 66.83696  ? 31  GLN A CA   1 
ATOM   441  C  C    . GLN A 1 31  ? 39.08200  -40.27100 66.39800 1.000 66.11845  ? 31  GLN A C    1 
ATOM   442  O  O    . GLN A 1 31  ? 38.42800  -39.61600 67.21300 1.000 60.81255  ? 31  GLN A O    1 
ATOM   443  C  CB   . GLN A 1 31  ? 41.47000  -40.70100 66.94000 1.000 65.80526  ? 31  GLN A CB   1 
ATOM   444  C  CG   . GLN A 1 31  ? 42.58500  -41.71000 67.17700 1.000 69.11092  ? 31  GLN A CG   1 
ATOM   445  C  CD   . GLN A 1 31  ? 43.92600  -41.05000 67.44200 1.000 72.29551  ? 31  GLN A CD   1 
ATOM   446  O  OE1  . GLN A 1 31  ? 44.10300  -40.35600 68.44300 1.000 71.07957  ? 31  GLN A OE1  1 
ATOM   447  N  NE2  . GLN A 1 31  ? 44.88000  -41.26500 66.54300 1.000 72.77715  ? 31  GLN A NE2  1 
ATOM   448  H  H    . GLN A 1 31  ? 40.42700  -42.42800 65.31400 1.000 80.07000  ? 31  GLN A H    1 
ATOM   449  H  HA   . GLN A 1 31  ? 39.80900  -41.55000 67.80200 1.000 80.32000  ? 31  GLN A HA   1 
ATOM   450  H  HB2  . GLN A 1 31  ? 41.64400  -40.26400 66.09100 1.000 79.08000  ? 31  GLN A HB2  1 
ATOM   451  H  HB3  . GLN A 1 31  ? 41.50200  -40.05100 67.66000 1.000 79.08000  ? 31  GLN A HB3  1 
ATOM   452  H  HG2  . GLN A 1 31  ? 42.36100  -42.25300 67.94900 1.000 83.05000  ? 31  GLN A HG2  1 
ATOM   453  H  HG3  . GLN A 1 31  ? 42.67700  -42.27100 66.39100 1.000 83.05000  ? 31  GLN A HG3  1 
ATOM   454  H  HE21 . GLN A 1 31  ? 44.72000  -41.75700 65.85600 1.000 87.45000  ? 31  GLN A HE21 1 
ATOM   455  H  HE22 . GLN A 1 31  ? 45.65700  -40.91300 66.64800 1.000 87.45000  ? 31  GLN A HE22 1 
ATOM   456  N  N    . PHE A 1 32  ? 38.95500  -40.09200 65.08000 1.000 63.67342  ? 32  PHE A N    1 
ATOM   457  C  CA   . PHE A 1 32  ? 38.10000  -39.05800 64.51700 1.000 57.69113  ? 32  PHE A CA   1 
ATOM   458  C  C    . PHE A 1 32  ? 36.92600  -39.59000 63.71000 1.000 60.98363  ? 32  PHE A C    1 
ATOM   459  O  O    . PHE A 1 32  ? 36.02500  -38.80900 63.38200 1.000 60.54937  ? 32  PHE A O    1 
ATOM   460  C  CB   . PHE A 1 32  ? 38.91100  -38.12600 63.60100 1.000 61.19681  ? 32  PHE A CB   1 
ATOM   461  C  CG   . PHE A 1 32  ? 40.05800  -37.44600 64.28200 1.000 59.07287  ? 32  PHE A CG   1 
ATOM   462  C  CD1  . PHE A 1 32  ? 39.98200  -37.09400 65.61800 1.000 59.65189  ? 32  PHE A CD1  1 
ATOM   463  C  CD2  . PHE A 1 32  ? 41.21100  -37.14800 63.57800 1.000 58.96233  ? 32  PHE A CD2  1 
ATOM   464  C  CE1  . PHE A 1 32  ? 41.03800  -36.46500 66.24100 1.000 61.24945  ? 32  PHE A CE1  1 
ATOM   465  C  CE2  . PHE A 1 32  ? 42.26900  -36.51800 64.19600 1.000 65.31573  ? 32  PHE A CE2  1 
ATOM   466  C  CZ   . PHE A 1 32  ? 42.17900  -36.17300 65.52900 1.000 63.32865  ? 32  PHE A CZ   1 
ATOM   467  H  H    . PHE A 1 32  ? 39.36200  -40.56500 64.48800 1.000 76.52000  ? 32  PHE A H    1 
ATOM   468  H  HA   . PHE A 1 32  ? 37.74600  -38.53700 65.25500 1.000 69.34000  ? 32  PHE A HA   1 
ATOM   469  H  HB2  . PHE A 1 32  ? 39.27100  -38.64800 62.86800 1.000 73.55000  ? 32  PHE A HB2  1 
ATOM   470  H  HB3  . PHE A 1 32  ? 38.32100  -37.43600 63.25900 1.000 73.55000  ? 32  PHE A HB3  1 
ATOM   471  H  HD1  . PHE A 1 32  ? 39.21100  -37.28500 66.10100 1.000 71.70000  ? 32  PHE A HD1  1 
ATOM   472  H  HD2  . PHE A 1 32  ? 41.27300  -37.37500 62.67900 1.000 70.87000  ? 32  PHE A HD2  1 
ATOM   473  H  HE1  . PHE A 1 32  ? 40.97900  -36.23700 67.14100 1.000 73.61000  ? 32  PHE A HE1  1 
ATOM   474  H  HE2  . PHE A 1 32  ? 43.04200  -36.32600 63.71600 1.000 78.49000  ? 32  PHE A HE2  1 
ATOM   475  H  HZ   . PHE A 1 32  ? 42.89000  -35.74400 65.94700 1.000 76.11000  ? 32  PHE A HZ   1 
ATOM   476  N  N    . GLY A 1 33  ? 36.90300  -40.87700 63.38000 1.000 64.37351  ? 33  GLY A N    1 
ATOM   477  C  CA   . GLY A 1 33  ? 35.96800  -41.38800 62.41000 1.000 58.04643  ? 33  GLY A CA   1 
ATOM   478  C  C    . GLY A 1 33  ? 36.54800  -41.24100 61.01800 1.000 57.84115  ? 33  GLY A C    1 
ATOM   479  O  O    . GLY A 1 33  ? 37.75100  -41.01500 60.85400 1.000 60.43883  ? 33  GLY A O    1 
ATOM   480  H  H    . GLY A 1 33  ? 37.42700  -41.47200 63.71300 1.000 77.36000  ? 33  GLY A H    1 
ATOM   481  H  HA2  . GLY A 1 33  ? 35.79100  -42.32600 62.58200 1.000 69.77000  ? 33  GLY A HA2  1 
ATOM   482  H  HA3  . GLY A 1 33  ? 35.13400  -40.89500 62.46000 1.000 69.77000  ? 33  GLY A HA3  1 
ATOM   483  N  N    . PRO A 1 34  ? 35.71200  -41.35300 59.98600 1.000 57.06210  ? 34  PRO A N    1 
ATOM   484  C  CA   . PRO A 1 34  ? 36.23100  -41.20900 58.61700 1.000 57.60164  ? 34  PRO A CA   1 
ATOM   485  C  C    . PRO A 1 34  ? 36.99500  -39.90600 58.45100 1.000 55.97776  ? 34  PRO A C    1 
ATOM   486  O  O    . PRO A 1 34  ? 36.45900  -38.82400 58.71100 1.000 56.43571  ? 34  PRO A O    1 
ATOM   487  C  CB   . PRO A 1 34  ? 34.97100  -41.25000 57.74400 1.000 54.86710  ? 34  PRO A CB   1 
ATOM   488  C  CG   . PRO A 1 34  ? 33.91500  -41.87300 58.59700 1.000 60.51778  ? 34  PRO A CG   1 
ATOM   489  C  CD   . PRO A 1 34  ? 34.25000  -41.53300 60.01700 1.000 56.75417  ? 34  PRO A CD   1 
ATOM   490  H  HA   . PRO A 1 34  ? 36.79500  -41.96000 58.37700 1.000 69.24000  ? 34  PRO A HA   1 
ATOM   491  H  HB2  . PRO A 1 34  ? 34.72000  -40.34900 57.48700 1.000 65.96000  ? 34  PRO A HB2  1 
ATOM   492  H  HB3  . PRO A 1 34  ? 35.13700  -41.78600 56.95300 1.000 65.96000  ? 34  PRO A HB3  1 
ATOM   493  H  HG2  . PRO A 1 34  ? 33.04900  -41.51100 58.35600 1.000 72.73000  ? 34  PRO A HG2  1 
ATOM   494  H  HG3  . PRO A 1 34  ? 33.92100  -42.83400 58.46800 1.000 72.73000  ? 34  PRO A HG3  1 
ATOM   495  H  HD2  . PRO A 1 34  ? 33.80700  -40.71400 60.28900 1.000 68.22000  ? 34  PRO A HD2  1 
ATOM   496  H  HD3  . PRO A 1 34  ? 34.00300  -42.25700 60.61300 1.000 68.22000  ? 34  PRO A HD3  1 
ATOM   497  N  N    . THR A 1 35  ? 38.25400  -40.00600 58.03500 1.000 56.60416  ? 35  THR A N    1 
ATOM   498  C  CA   . THR A 1 35  ? 39.15100  -38.86300 57.95100 1.000 57.75692  ? 35  THR A CA   1 
ATOM   499  C  C    . THR A 1 35  ? 39.76800  -38.80600 56.56400 1.000 58.10697  ? 35  THR A C    1 
ATOM   500  O  O    . THR A 1 35  ? 40.11500  -39.84000 55.98600 1.000 58.43595  ? 35  THR A O    1 
ATOM   501  C  CB   . THR A 1 35  ? 40.26000  -38.94600 59.00600 1.000 57.04895  ? 35  THR A CB   1 
ATOM   502  O  OG1  . THR A 1 35  ? 39.67800  -39.14200 60.30000 1.000 59.53609  ? 35  THR A OG1  1 
ATOM   503  C  CG2  . THR A 1 35  ? 41.09300  -37.67200 59.00900 1.000 59.58609  ? 35  THR A CG2  1 
ATOM   504  H  H    . THR A 1 35  ? 38.61900  -40.74500 57.78900 1.000 68.04000  ? 35  THR A H    1 
ATOM   505  H  HA   . THR A 1 35  ? 38.64800  -38.04700 58.09900 1.000 69.42000  ? 35  THR A HA   1 
ATOM   506  H  HB   . THR A 1 35  ? 40.84700  -39.69000 58.80000 1.000 68.57000  ? 35  THR A HB   1 
ATOM   507  H  HG1  . THR A 1 35  ? 39.23100  -39.85300 60.30900 1.000 71.56000  ? 35  THR A HG1  1 
ATOM   508  H  HG21 . THR A 1 35  ? 41.71100  -37.68100 59.75700 1.000 71.62000  ? 35  THR A HG21 1 
ATOM   509  H  HG22 . THR A 1 35  ? 41.59800  -37.60300 58.18400 1.000 71.62000  ? 35  THR A HG22 1 
ATOM   510  H  HG23 . THR A 1 35  ? 40.51400  -36.89700 59.08900 1.000 71.62000  ? 35  THR A HG23 1 
ATOM   511  N  N    . TYR A 1 36  ? 39.91200  -37.59300 56.04000 1.000 54.17492  ? 36  TYR A N    1 
ATOM   512  C  CA   . TYR A 1 36  ? 40.45900  -37.38100 54.70900 1.000 56.32517  ? 36  TYR A CA   1 
ATOM   513  C  C    . TYR A 1 36  ? 41.53600  -36.31000 54.76000 1.000 55.74879  ? 36  TYR A C    1 
ATOM   514  O  O    . TYR A 1 36  ? 41.43400  -35.34600 55.52400 1.000 54.35389  ? 36  TYR A O    1 
ATOM   515  C  CB   . TYR A 1 36  ? 39.35300  -36.98400 53.72200 1.000 55.04871  ? 36  TYR A CB   1 
ATOM   516  C  CG   . TYR A 1 36  ? 38.16500  -37.92200 53.74700 1.000 51.45617  ? 36  TYR A CG   1 
ATOM   517  C  CD1  . TYR A 1 36  ? 37.11900  -37.72600 54.63800 1.000 53.55905  ? 36  TYR A CD1  1 
ATOM   518  C  CD2  . TYR A 1 36  ? 38.09500  -39.00800 52.88600 1.000 54.79078  ? 36  TYR A CD2  1 
ATOM   519  C  CE1  . TYR A 1 36  ? 36.03600  -38.58100 54.66800 1.000 51.55881  ? 36  TYR A CE1  1 
ATOM   520  C  CE2  . TYR A 1 36  ? 37.01400  -39.87000 52.90900 1.000 52.60894  ? 36  TYR A CE2  1 
ATOM   521  C  CZ   . TYR A 1 36  ? 35.98900  -39.65200 53.80200 1.000 54.91185  ? 36  TYR A CZ   1 
ATOM   522  O  OH   . TYR A 1 36  ? 34.91000  -40.50500 53.83000 1.000 60.35724  ? 36  TYR A OH   1 
ATOM   523  H  H    . TYR A 1 36  ? 39.69600  -36.86600 56.44600 1.000 65.13000  ? 36  TYR A H    1 
ATOM   524  H  HA   . TYR A 1 36  ? 40.87300  -38.19700 54.38900 1.000 67.70000  ? 36  TYR A HA   1 
ATOM   525  H  HB2  . TYR A 1 36  ? 39.03500  -36.09500 53.94700 1.000 66.17000  ? 36  TYR A HB2  1 
ATOM   526  H  HB3  . TYR A 1 36  ? 39.71800  -36.98800 52.82400 1.000 66.17000  ? 36  TYR A HB3  1 
ATOM   527  H  HD1  . TYR A 1 36  ? 37.14900  -37.00600 55.22600 1.000 64.38000  ? 36  TYR A HD1  1 
ATOM   528  H  HD2  . TYR A 1 36  ? 38.78700  -39.15800 52.28300 1.000 65.86000  ? 36  TYR A HD2  1 
ATOM   529  H  HE1  . TYR A 1 36  ? 35.34200  -38.43600 55.27000 1.000 61.99000  ? 36  TYR A HE1  1 
ATOM   530  H  HE2  . TYR A 1 36  ? 36.98000  -40.59200 52.32400 1.000 63.24000  ? 36  TYR A HE2  1 
ATOM   531  H  HH   . TYR A 1 36  ? 35.02300  -41.12900 53.27900 1.000 72.54000  ? 36  TYR A HH   1 
ATOM   532  N  N    . LEU A 1 37  ? 42.57400  -36.49400 53.94600 1.000 57.38320  ? 37  LEU A N    1 
ATOM   533  C  CA   . LEU A 1 37  ? 43.67000  -35.53700 53.80500 1.000 58.22014  ? 37  LEU A CA   1 
ATOM   534  C  C    . LEU A 1 37  ? 43.71400  -35.10400 52.34300 1.000 63.61026  ? 37  LEU A C    1 
ATOM   535  O  O    . LEU A 1 37  ? 44.17000  -35.85800 51.47900 1.000 62.46538  ? 37  LEU A O    1 
ATOM   536  C  CB   . LEU A 1 37  ? 44.99600  -36.14900 54.24500 1.000 57.57532  ? 37  LEU A CB   1 
ATOM   537  C  CG   . LEU A 1 37  ? 46.22200  -35.23500 54.17500 1.000 62.03902  ? 37  LEU A CG   1 
ATOM   538  C  CD1  . LEU A 1 37  ? 46.03500  -34.00700 55.05500 1.000 58.31752  ? 37  LEU A CD1  1 
ATOM   539  C  CD2  . LEU A 1 37  ? 47.47700  -35.99800 54.57500 1.000 62.03639  ? 37  LEU A CD2  1 
ATOM   540  H  H    . LEU A 1 37  ? 42.66800  -37.18900 53.44800 1.000 68.97000  ? 37  LEU A H    1 
ATOM   541  H  HA   . LEU A 1 37  ? 43.49600  -34.76000 54.35900 1.000 69.98000  ? 37  LEU A HA   1 
ATOM   542  H  HB2  . LEU A 1 37  ? 44.90500  -36.43400 55.16800 1.000 69.20000  ? 37  LEU A HB2  1 
ATOM   543  H  HB3  . LEU A 1 37  ? 45.17700  -36.91500 53.67800 1.000 69.20000  ? 37  LEU A HB3  1 
ATOM   544  H  HG   . LEU A 1 37  ? 46.33200  -34.92900 53.26100 1.000 74.56000  ? 37  LEU A HG   1 
ATOM   545  H  HD11 . LEU A 1 37  ? 46.87200  -33.51800 55.09700 1.000 70.10000  ? 37  LEU A HD11 1 
ATOM   546  H  HD12 . LEU A 1 37  ? 45.34300  -33.44500 54.67000 1.000 70.10000  ? 37  LEU A HD12 1 
ATOM   547  H  HD13 . LEU A 1 37  ? 45.77300  -34.29200 55.94400 1.000 70.10000  ? 37  LEU A HD13 1 
ATOM   548  H  HD21 . LEU A 1 37  ? 48.23800  -35.39900 54.52900 1.000 74.56000  ? 37  LEU A HD21 1 
ATOM   549  H  HD22 . LEU A 1 37  ? 47.37000  -36.32900 55.48000 1.000 74.56000  ? 37  LEU A HD22 1 
ATOM   550  H  HD23 . LEU A 1 37  ? 47.60300  -36.74100 53.96400 1.000 74.56000  ? 37  LEU A HD23 1 
ATOM   551  N  N    . ASP A 1 38  ? 43.23700  -33.89200 52.06700 1.000 71.80335  ? 38  ASP A N    1 
ATOM   552  C  CA   . ASP A 1 38  ? 43.20100  -33.36400 50.70500 1.000 79.02526  ? 38  ASP A CA   1 
ATOM   553  C  C    . ASP A 1 38  ? 42.47900  -34.32800 49.76500 1.000 73.20351  ? 38  ASP A C    1 
ATOM   554  O  O    . ASP A 1 38  ? 42.84500  -34.48500 48.59800 1.000 78.16727  ? 38  ASP A O    1 
ATOM   555  C  CB   . ASP A 1 38  ? 44.61500  -33.06600 50.20100 1.000 92.67953  ? 38  ASP A CB   1 
ATOM   556  C  CG   . ASP A 1 38  ? 44.66700  -31.86600 49.26700 1.000 108.16560 ? 38  ASP A CG   1 
ATOM   557  O  OD1  . ASP A 1 38  ? 43.65900  -31.13400 49.16200 1.000 121.61985 ? 38  ASP A OD1  1 
ATOM   558  O  OD2  . ASP A 1 38  ? 45.72300  -31.65400 48.63500 1.000 103.56768 ? 38  ASP A OD2  1 
ATOM   559  H  H    . ASP A 1 38  ? 42.92500  -33.35000 52.65800 1.000 86.27000  ? 38  ASP A H    1 
ATOM   560  H  HA   . ASP A 1 38  ? 42.70100  -32.53200 50.70900 1.000 94.95000  ? 38  ASP A HA   1 
ATOM   561  H  HB2  . ASP A 1 38  ? 45.18800  -32.88000 50.96000 1.000 111.33000 ? 38  ASP A HB2  1 
ATOM   562  H  HB3  . ASP A 1 38  ? 44.94600  -33.83800 49.71500 1.000 111.33000 ? 38  ASP A HB3  1 
ATOM   563  N  N    . GLY A 1 39  ? 41.44100  -34.98600 50.28400 1.000 66.71326  ? 39  GLY A N    1 
ATOM   564  C  CA   . GLY A 1 39  ? 40.63700  -35.91000 49.52000 1.000 62.82859  ? 39  GLY A CA   1 
ATOM   565  C  C    . GLY A 1 39  ? 40.98900  -37.37200 49.71400 1.000 63.47077  ? 39  GLY A C    1 
ATOM   566  O  O    . GLY A 1 39  ? 40.13900  -38.23500 49.46800 1.000 61.77583  ? 39  GLY A O    1 
ATOM   567  H  H    . GLY A 1 39  ? 41.18500  -34.90400 51.10000 1.000 80.17000  ? 39  GLY A H    1 
ATOM   568  H  HA2  . GLY A 1 39  ? 39.70700  -35.79400 49.77100 1.000 75.51000  ? 39  GLY A HA2  1 
ATOM   569  H  HA3  . GLY A 1 39  ? 40.73700  -35.70500 48.57700 1.000 75.51000  ? 39  GLY A HA3  1 
ATOM   570  N  N    . ALA A 1 40  ? 42.21200  -37.67100 50.14600 1.000 62.70489  ? 40  ALA A N    1 
ATOM   571  C  CA   . ALA A 1 40  ? 42.63500  -39.05200 50.33700 1.000 64.87883  ? 40  ALA A CA   1 
ATOM   572  C  C    . ALA A 1 40  ? 42.08200  -39.59300 51.64900 1.000 61.50474  ? 40  ALA A C    1 
ATOM   573  O  O    . ALA A 1 40  ? 42.16000  -38.92800 52.68500 1.000 63.41813  ? 40  ALA A O    1 
ATOM   574  C  CB   . ALA A 1 40  ? 44.16000  -39.14700 50.32600 1.000 59.56767  ? 40  ALA A CB   1 
ATOM   575  H  H    . ALA A 1 40  ? 42.81600  -37.08900 50.33500 1.000 75.36000  ? 40  ALA A H    1 
ATOM   576  H  HA   . ALA A 1 40  ? 42.29100  -39.59700 49.61200 1.000 77.97000  ? 40  ALA A HA   1 
ATOM   577  H  HB1  . ALA A 1 40  ? 44.41900  -40.07200 50.46100 1.000 71.59000  ? 40  ALA A HB1  1 
ATOM   578  H  HB2  . ALA A 1 40  ? 44.49000  -38.83300 49.47000 1.000 71.59000  ? 40  ALA A HB2  1 
ATOM   579  H  HB3  . ALA A 1 40  ? 44.51600  -38.59700 51.04100 1.000 71.59000  ? 40  ALA A HB3  1 
ATOM   580  N  N    . ASP A 1 41  ? 41.53400  -40.80600 51.60500 1.000 63.03651  ? 41  ASP A N    1 
ATOM   581  C  CA   . ASP A 1 41  ? 40.91600  -41.42000 52.77600 1.000 65.73420  ? 41  ASP A CA   1 
ATOM   582  C  C    . ASP A 1 41  ? 42.00400  -42.00700 53.66800 1.000 62.96808  ? 41  ASP A C    1 
ATOM   583  O  O    . ASP A 1 41  ? 42.57300  -43.05800 53.35500 1.000 68.77404  ? 41  ASP A O    1 
ATOM   584  C  CB   . ASP A 1 41  ? 39.91900  -42.49400 52.34900 1.000 64.53142  ? 41  ASP A CB   1 
ATOM   585  C  CG   . ASP A 1 41  ? 39.06100  -42.98800 53.50100 1.000 68.79509  ? 41  ASP A CG   1 
ATOM   586  O  OD1  . ASP A 1 41  ? 39.54700  -42.99800 54.65000 1.000 64.21033  ? 41  ASP A OD1  1 
ATOM   587  O  OD2  . ASP A 1 41  ? 37.89700  -43.36700 53.25500 1.000 74.39050  ? 41  ASP A OD2  1 
ATOM   588  H  H    . ASP A 1 41  ? 41.50700  -41.29800 50.90000 1.000 75.76000  ? 41  ASP A H    1 
ATOM   589  H  HA   . ASP A 1 41  ? 40.44100  -40.74100 53.28000 1.000 78.99000  ? 41  ASP A HA   1 
ATOM   590  H  HB2  . ASP A 1 41  ? 39.33000  -42.12700 51.67100 1.000 77.55000  ? 41  ASP A HB2  1 
ATOM   591  H  HB3  . ASP A 1 41  ? 40.40500  -43.25200 51.99000 1.000 77.55000  ? 41  ASP A HB3  1 
ATOM   592  N  N    . VAL A 1 42  ? 42.28700  -41.33500 54.78100 1.000 62.70225  ? 42  VAL A N    1 
ATOM   593  C  CA   . VAL A 1 42  ? 43.27600  -41.80200 55.74400 1.000 63.73133  ? 42  VAL A CA   1 
ATOM   594  C  C    . VAL A 1 42  ? 42.60900  -42.46900 56.94900 1.000 68.51874  ? 42  VAL A C    1 
ATOM   595  O  O    . VAL A 1 42  ? 43.21800  -42.57300 58.01300 1.000 71.01115  ? 42  VAL A O    1 
ATOM   596  C  CB   . VAL A 1 42  ? 44.20400  -40.66100 56.19200 1.000 64.22875  ? 42  VAL A CB   1 
ATOM   597  C  CG1  . VAL A 1 42  ? 44.91300  -40.04800 54.99500 1.000 62.60487  ? 42  VAL A CG1  1 
ATOM   598  C  CG2  . VAL A 1 42  ? 43.42300  -39.59900 56.96300 1.000 60.14669  ? 42  VAL A CG2  1 
ATOM   599  H  H    . VAL A 1 42  ? 41.91300  -40.59400 55.00300 1.000 75.36000  ? 42  VAL A H    1 
ATOM   600  H  HA   . VAL A 1 42  ? 43.82100  -42.47400 55.30700 1.000 76.59000  ? 42  VAL A HA   1 
ATOM   601  H  HB   . VAL A 1 42  ? 44.87900  -41.02500 56.78700 1.000 77.19000  ? 42  VAL A HB   1 
ATOM   602  H  HG11 . VAL A 1 42  ? 45.52600  -39.36400 55.30700 1.000 75.24000  ? 42  VAL A HG11 1 
ATOM   603  H  HG12 . VAL A 1 42  ? 45.40300  -40.74300 54.52800 1.000 75.24000  ? 42  VAL A HG12 1 
ATOM   604  H  HG13 . VAL A 1 42  ? 44.25200  -39.65500 54.40400 1.000 75.24000  ? 42  VAL A HG13 1 
ATOM   605  H  HG21 . VAL A 1 42  ? 44.01100  -38.85000 57.15100 1.000 72.29000  ? 42  VAL A HG21 1 
ATOM   606  H  HG22 . VAL A 1 42  ? 42.67400  -39.30400 56.42300 1.000 72.29000  ? 42  VAL A HG22 1 
ATOM   607  H  HG23 . VAL A 1 42  ? 43.10200  -39.98300 57.79400 1.000 72.29000  ? 42  VAL A HG23 1 
ATOM   608  N  N    . THR A 1 43  ? 41.36400  -42.92700 56.79600 1.000 66.80011  ? 43  THR A N    1 
ATOM   609  C  CA   . THR A 1 43  ? 40.63900  -43.49800 57.92700 1.000 66.28426  ? 43  THR A CA   1 
ATOM   610  C  C    . THR A 1 43  ? 41.39600  -44.67100 58.53800 1.000 70.55583  ? 43  THR A C    1 
ATOM   611  O  O    . THR A 1 43  ? 41.47200  -44.79700 59.76600 1.000 70.21631  ? 43  THR A O    1 
ATOM   612  C  CB   . THR A 1 43  ? 39.24200  -43.93900 57.48400 1.000 63.48130  ? 43  THR A CB   1 
ATOM   613  O  OG1  . THR A 1 43  ? 38.55200  -42.82900 56.89700 1.000 62.58119  ? 43  THR A OG1  1 
ATOM   614  C  CG2  . THR A 1 43  ? 38.43900  -44.46300 58.66800 1.000 59.60451  ? 43  THR A CG2  1 
ATOM   615  H  H    . THR A 1 43  ? 40.92300  -42.91700 56.05700 1.000 80.27000  ? 43  THR A H    1 
ATOM   616  H  HA   . THR A 1 43  ? 40.54100  -42.81600 58.60900 1.000 79.65000  ? 43  THR A HA   1 
ATOM   617  H  HB   . THR A 1 43  ? 39.32300  -44.65300 56.83100 1.000 76.29000  ? 43  THR A HB   1 
ATOM   618  H  HG1  . THR A 1 43  ? 38.97700  -42.54500 56.23100 1.000 75.21000  ? 43  THR A HG1  1 
ATOM   619  H  HG21 . THR A 1 43  ? 37.51100  -44.58200 58.41400 1.000 71.64000  ? 43  THR A HG21 1 
ATOM   620  H  HG22 . THR A 1 43  ? 38.79700  -45.31600 58.96000 1.000 71.64000  ? 43  THR A HG22 1 
ATOM   621  H  HG23 . THR A 1 43  ? 38.48600  -43.83400 59.40500 1.000 71.64000  ? 43  THR A HG23 1 
ATOM   622  N  N    . LYS A 1 44  ? 41.96100  -45.53900 57.70200 1.000 72.18760  ? 44  LYS A N    1 
ATOM   623  C  CA   . LYS A 1 44  ? 42.67400  -46.72000 58.16700 1.000 75.31956  ? 44  LYS A CA   1 
ATOM   624  C  C    . LYS A 1 44  ? 44.17600  -46.49700 58.29900 1.000 78.22780  ? 44  LYS A C    1 
ATOM   625  O  O    . LYS A 1 44  ? 44.90000  -47.43900 58.63700 1.000 75.86962  ? 44  LYS A O    1 
ATOM   626  C  CB   . LYS A 1 44  ? 42.41500  -47.89300 57.21600 1.000 78.71470  ? 44  LYS A CB   1 
ATOM   627  C  CG   . LYS A 1 44  ? 41.00800  -48.46600 57.30000 1.000 80.44386  ? 44  LYS A CG   1 
ATOM   628  C  CD   . LYS A 1 44  ? 40.64200  -49.22300 56.03100 1.000 87.34205  ? 44  LYS A CD   1 
ATOM   629  C  CE   . LYS A 1 44  ? 39.76000  -50.42800 56.32600 1.000 92.09525  ? 44  LYS A CE   1 
ATOM   630  N  NZ   . LYS A 1 44  ? 39.06800  -50.92900 55.10400 1.000 86.94200  ? 44  LYS A NZ   1 
ATOM   631  H  H    . LYS A 1 44  ? 41.94300  -45.46200 56.84600 1.000 86.74000  ? 44  LYS A H    1 
ATOM   632  H  HA   . LYS A 1 44  ? 42.33400  -46.96000 59.04300 1.000 90.50000  ? 44  LYS A HA   1 
ATOM   633  H  HB2  . LYS A 1 44  ? 42.55600  -47.59100 56.30500 1.000 94.57000  ? 44  LYS A HB2  1 
ATOM   634  H  HB3  . LYS A 1 44  ? 43.03700  -48.60700 57.42800 1.000 94.57000  ? 44  LYS A HB3  1 
ATOM   635  H  HG2  . LYS A 1 44  ? 40.95500  -49.08000 58.04900 1.000 96.65000  ? 44  LYS A HG2  1 
ATOM   636  H  HG3  . LYS A 1 44  ? 40.37300  -47.74200 57.41800 1.000 96.65000  ? 44  LYS A HG3  1 
ATOM   637  H  HD2  . LYS A 1 44  ? 40.15700  -48.63200 55.43300 1.000 104.92000 ? 44  LYS A HD2  1 
ATOM   638  H  HD3  . LYS A 1 44  ? 41.45200  -49.53800 55.60000 1.000 104.92000 ? 44  LYS A HD3  1 
ATOM   639  H  HE2  . LYS A 1 44  ? 40.30900  -51.14600 56.67900 1.000 110.63000 ? 44  LYS A HE2  1 
ATOM   640  H  HE3  . LYS A 1 44  ? 39.08400  -50.17700 56.97600 1.000 110.63000 ? 44  LYS A HE3  1 
ATOM   641  H  HZ1  . LYS A 1 44  ? 38.56100  -51.63200 55.30800 1.000 104.44000 ? 44  LYS A HZ1  1 
ATOM   642  H  HZ2  . LYS A 1 44  ? 38.55100  -50.29000 54.76300 1.000 104.44000 ? 44  LYS A HZ2  1 
ATOM   643  H  HZ3  . LYS A 1 44  ? 39.66700  -51.17300 54.49300 1.000 104.44000 ? 44  LYS A HZ3  1 
ATOM   644  N  N    . ILE A 1 45  ? 44.65800  -45.28600 58.04300 1.000 80.08329  ? 45  ILE A N    1 
ATOM   645  C  CA   . ILE A 1 45  ? 46.08000  -44.97000 58.12000 1.000 77.34875  ? 45  ILE A CA   1 
ATOM   646  C  C    . ILE A 1 45  ? 46.39400  -44.45300 59.51600 1.000 76.33547  ? 45  ILE A C    1 
ATOM   647  O  O    . ILE A 1 45  ? 45.54800  -43.85300 60.18700 1.000 74.55894  ? 45  ILE A O    1 
ATOM   648  C  CB   . ILE A 1 45  ? 46.46600  -43.94800 57.02700 1.000 82.35987  ? 45  ILE A CB   1 
ATOM   649  C  CG1  . ILE A 1 45  ? 46.86400  -44.68100 55.74200 1.000 84.69963  ? 45  ILE A CG1  1 
ATOM   650  C  CG2  . ILE A 1 45  ? 47.60500  -43.03500 57.48600 1.000 82.55990  ? 45  ILE A CG2  1 
ATOM   651  C  CD1  . ILE A 1 45  ? 46.96700  -43.78400 54.52400 1.000 86.19981  ? 45  ILE A CD1  1 
ATOM   652  H  H    . ILE A 1 45  ? 44.17100  -44.61500 57.81700 1.000 96.21000  ? 45  ILE A H    1 
ATOM   653  H  HA   . ILE A 1 45  ? 46.60000  -45.77600 57.97800 1.000 92.93000  ? 45  ILE A HA   1 
ATOM   654  H  HB   . ILE A 1 45  ? 45.69000  -43.39300 56.85600 1.000 98.95000  ? 45  ILE A HB   1 
ATOM   655  H  HG12 . ILE A 1 45  ? 47.73000  -45.09600 55.87700 1.000 101.75000 ? 45  ILE A HG12 1 
ATOM   656  H  HG13 . ILE A 1 45  ? 46.19700  -45.36000 55.55300 1.000 101.75000 ? 45  ILE A HG13 1 
ATOM   657  H  HG21 . ILE A 1 45  ? 47.83400  -42.42800 56.76400 1.000 99.18000  ? 45  ILE A HG21 1 
ATOM   658  H  HG22 . ILE A 1 45  ? 47.31300  -42.53000 58.26100 1.000 99.18000  ? 45  ILE A HG22 1 
ATOM   659  H  HG23 . ILE A 1 45  ? 48.37400  -43.58000 57.71600 1.000 99.18000  ? 45  ILE A HG23 1 
ATOM   660  H  HD11 . ILE A 1 45  ? 47.21700  -44.32200 53.75600 1.000 103.55000 ? 45  ILE A HD11 1 
ATOM   661  H  HD12 . ILE A 1 45  ? 46.10700  -43.36400 54.36700 1.000 103.55000 ? 45  ILE A HD12 1 
ATOM   662  H  HD13 . ILE A 1 45  ? 47.64200  -43.10700 54.68700 1.000 103.55000 ? 45  ILE A HD13 1 
ATOM   663  N  N    . LYS A 1 46  ? 47.64600  -44.69500 59.96900 1.000 82.44673  ? 46  LYS A N    1 
ATOM   664  C  CA   . LYS A 1 46  ? 48.10200  -44.15500 61.24000 1.000 78.61469  ? 46  LYS A CA   1 
ATOM   665  C  C    . LYS A 1 46  ? 48.89500  -42.87100 61.01600 1.000 79.59902  ? 46  LYS A C    1 
ATOM   666  O  O    . LYS A 1 46  ? 49.53100  -42.70200 59.97100 1.000 82.67307  ? 46  LYS A O    1 
ATOM   667  C  CB   . LYS A 1 46  ? 48.97200  -45.17300 61.98100 1.000 84.30748  ? 46  LYS A CB   1 
ATOM   668  C  CG   . LYS A 1 46  ? 48.19100  -46.05500 62.94400 1.000 86.16559  ? 46  LYS A CG   1 
ATOM   669  C  CD   . LYS A 1 46  ? 48.68800  -47.49100 62.92000 1.000 83.40737  ? 46  LYS A CD   1 
ATOM   670  C  CE   . LYS A 1 46  ? 48.00600  -48.32400 63.99300 1.000 88.61326  ? 46  LYS A CE   1 
ATOM   671  N  NZ   . LYS A 1 46  ? 48.76300  -49.56500 64.31800 1.000 93.32698  ? 46  LYS A NZ   1 
ATOM   672  H  H    . LYS A 1 46  ? 48.23400  -45.16500 59.55300 1.000 99.05000  ? 46  LYS A H    1 
ATOM   673  H  HA   . LYS A 1 46  ? 47.34000  -43.95200 61.80400 1.000 94.45000  ? 46  LYS A HA   1 
ATOM   674  H  HB2  . LYS A 1 46  ? 49.40000  -45.75100 61.33000 1.000 101.28000 ? 46  LYS A HB2  1 
ATOM   675  H  HB3  . LYS A 1 46  ? 49.64300  -44.69600 62.49400 1.000 101.28000 ? 46  LYS A HB3  1 
ATOM   676  H  HG2  . LYS A 1 46  ? 48.29300  -45.71300 63.84600 1.000 103.51000 ? 46  LYS A HG2  1 
ATOM   677  H  HG3  . LYS A 1 46  ? 47.25500  -46.05400 62.69200 1.000 103.51000 ? 46  LYS A HG3  1 
ATOM   678  H  HD2  . LYS A 1 46  ? 48.49300  -47.88600 62.05600 1.000 100.20000 ? 46  LYS A HD2  1 
ATOM   679  H  HD3  . LYS A 1 46  ? 49.64400  -47.50500 63.08300 1.000 100.20000 ? 46  LYS A HD3  1 
ATOM   680  H  HE2  . LYS A 1 46  ? 47.93000  -47.79700 64.80400 1.000 106.44000 ? 46  LYS A HE2  1 
ATOM   681  H  HE3  . LYS A 1 46  ? 47.12400  -48.58300 63.68200 1.000 106.44000 ? 46  LYS A HE3  1 
ATOM   682  H  HZ1  . LYS A 1 46  ? 48.33900  -50.02400 64.95200 1.000 112.10000 ? 46  LYS A HZ1  1 
ATOM   683  H  HZ2  . LYS A 1 46  ? 48.83700  -50.07500 63.59300 1.000 112.10000 ? 46  LYS A HZ2  1 
ATOM   684  H  HZ3  . LYS A 1 46  ? 49.57800  -49.35700 64.61000 1.000 112.10000 ? 46  LYS A HZ3  1 
ATOM   685  N  N    . PRO A 1 47  ? 48.88400  -41.94400 61.97400 1.000 77.44350  ? 47  PRO A N    1 
ATOM   686  C  CA   . PRO A 1 47  ? 49.50600  -40.63600 61.73000 1.000 77.91724  ? 47  PRO A CA   1 
ATOM   687  C  C    . PRO A 1 47  ? 51.00500  -40.74600 61.49000 1.000 79.44110  ? 47  PRO A C    1 
ATOM   688  O  O    . PRO A 1 47  ? 51.71700  -41.46700 62.19100 1.000 79.27793  ? 47  PRO A O    1 
ATOM   689  C  CB   . PRO A 1 47  ? 49.20100  -39.84800 63.01200 1.000 77.36980  ? 47  PRO A CB   1 
ATOM   690  C  CG   . PRO A 1 47  ? 48.08600  -40.58000 63.67500 1.000 76.94080  ? 47  PRO A CG   1 
ATOM   691  C  CD   . PRO A 1 47  ? 48.25900  -42.01700 63.30600 1.000 78.18832  ? 47  PRO A CD   1 
ATOM   692  H  HA   . PRO A 1 47  ? 49.08900  -40.20800 60.96600 1.000 93.61000  ? 47  PRO A HA   1 
ATOM   693  H  HB2  . PRO A 1 47  ? 49.98700  -39.82900 63.58000 1.000 92.96000  ? 47  PRO A HB2  1 
ATOM   694  H  HB3  . PRO A 1 47  ? 48.93400  -38.94400 62.78400 1.000 92.96000  ? 47  PRO A HB3  1 
ATOM   695  H  HG2  . PRO A 1 47  ? 48.14500  -40.46300 64.63600 1.000 92.44000  ? 47  PRO A HG2  1 
ATOM   696  H  HG3  . PRO A 1 47  ? 47.23600  -40.24200 63.35100 1.000 92.44000  ? 47  PRO A HG3  1 
ATOM   697  H  HD2  . PRO A 1 47  ? 48.84000  -42.46900 63.93700 1.000 93.94000  ? 47  PRO A HD2  1 
ATOM   698  H  HD3  . PRO A 1 47  ? 47.40200  -42.46900 63.26200 1.000 93.94000  ? 47  PRO A HD3  1 
ATOM   699  N  N    . HIS A 1 48  ? 51.47500  -40.01400 60.48500 1.000 85.82082  ? 48  HIS A N    1 
ATOM   700  C  CA   . HIS A 1 48  ? 52.89700  -39.87000 60.21700 1.000 89.24754  ? 48  HIS A CA   1 
ATOM   701  C  C    . HIS A 1 48  ? 53.42800  -38.61300 60.89600 1.000 84.84965  ? 48  HIS A C    1 
ATOM   702  O  O    . HIS A 1 48  ? 52.67100  -37.72500 61.29600 1.000 80.95444  ? 48  HIS A O    1 
ATOM   703  C  CB   . HIS A 1 48  ? 53.17100  -39.78700 58.71300 1.000 88.26058  ? 48  HIS A CB   1 
ATOM   704  C  CG   . HIS A 1 48  ? 52.63300  -40.94200 57.92700 1.000 92.95325  ? 48  HIS A CG   1 
ATOM   705  N  ND1  . HIS A 1 48  ? 52.68500  -40.98700 56.55000 1.000 98.78553  ? 48  HIS A ND1  1 
ATOM   706  C  CD2  . HIS A 1 48  ? 52.03700  -42.09300 58.31800 1.000 97.00110  ? 48  HIS A CD2  1 
ATOM   707  C  CE1  . HIS A 1 48  ? 52.14300  -42.11500 56.12700 1.000 101.35689 ? 48  HIS A CE1  1 
ATOM   708  N  NE2  . HIS A 1 48  ? 51.74200  -42.80400 57.18000 1.000 100.97790 ? 48  HIS A NE2  1 
ATOM   709  H  H    . HIS A 1 48  ? 50.97800  -39.58100 59.93300 1.000 103.10000 ? 48  HIS A H    1 
ATOM   710  H  HA   . HIS A 1 48  ? 53.36400  -40.64700 60.56400 1.000 107.21000 ? 48  HIS A HA   1 
ATOM   711  H  HB2  . HIS A 1 48  ? 52.76100  -38.97900 58.36700 1.000 106.03000 ? 48  HIS A HB2  1 
ATOM   712  H  HB3  . HIS A 1 48  ? 54.13100  -39.75800 58.57400 1.000 106.03000 ? 48  HIS A HB3  1 
ATOM   713  H  HD2  . HIS A 1 48  ? 51.86100  -42.35300 59.19400 1.000 116.52000 ? 48  HIS A HD2  1 
ATOM   714  H  HE1  . HIS A 1 48  ? 52.05800  -42.37900 55.24000 1.000 121.74000 ? 48  HIS A HE1  1 
ATOM   715  H  HE2  . HIS A 1 48  ? 51.35700  -43.57300 57.15700 1.000 121.29000 ? 48  HIS A HE2  1 
ATOM   716  N  N    . ASN A 1 49  ? 54.75500  -38.54100 61.01700 1.000 86.49195  ? 49  ASN A N    1 
ATOM   717  C  CA   . ASN A 1 49  ? 55.37000  -37.32000 61.52200 1.000 86.77093  ? 49  ASN A CA   1 
ATOM   718  C  C    . ASN A 1 49  ? 55.16300  -36.16100 60.55800 1.000 80.74652  ? 49  ASN A C    1 
ATOM   719  O  O    . ASN A 1 49  ? 54.99400  -35.01600 60.99200 1.000 81.22816  ? 49  ASN A O    1 
ATOM   720  C  CB   . ASN A 1 49  ? 56.86000  -37.54700 61.77200 1.000 89.35545  ? 49  ASN A CB   1 
ATOM   721  C  CG   . ASN A 1 49  ? 57.11700  -38.49600 62.92400 1.000 93.68492  ? 49  ASN A CG   1 
ATOM   722  O  OD1  . ASN A 1 49  ? 57.68200  -39.57500 62.74100 1.000 100.29887 ? 49  ASN A OD1  1 
ATOM   723  N  ND2  . ASN A 1 49  ? 56.69400  -38.10200 64.11900 1.000 94.63503  ? 49  ASN A ND2  1 
ATOM   724  H  H    . ASN A 1 49  ? 55.30500  -39.17100 60.81800 1.000 103.90000 ? 49  ASN A H    1 
ATOM   725  H  HA   . ASN A 1 49  ? 54.96100  -37.08700 62.37000 1.000 104.24000 ? 49  ASN A HA   1 
ATOM   726  H  HB2  . ASN A 1 49  ? 57.26100  -37.92600 60.97400 1.000 107.34000 ? 49  ASN A HB2  1 
ATOM   727  H  HB3  . ASN A 1 49  ? 57.27900  -36.69800 61.98200 1.000 107.34000 ? 49  ASN A HB3  1 
ATOM   728  H  HD21 . ASN A 1 49  ? 56.29900  -37.34300 64.20700 1.000 113.68000 ? 49  ASN A HD21 1 
ATOM   729  H  HD22 . ASN A 1 49  ? 56.81600  -38.60600 64.80600 1.000 113.68000 ? 49  ASN A HD22 1 
ATOM   730  N  N    . SER A 1 50  ? 55.16500  -36.43700 59.25200 1.000 83.09154  ? 50  SER A N    1 
ATOM   731  C  CA   . SER A 1 50  ? 54.90900  -35.40900 58.25300 1.000 81.17552  ? 50  SER A CA   1 
ATOM   732  C  C    . SER A 1 50  ? 53.48900  -34.86300 58.32000 1.000 75.00636  ? 50  SER A C    1 
ATOM   733  O  O    . SER A 1 50  ? 53.20700  -33.84400 57.68100 1.000 73.21404  ? 50  SER A O    1 
ATOM   734  C  CB   . SER A 1 50  ? 55.17300  -35.96700 56.85200 1.000 83.00995  ? 50  SER A CB   1 
ATOM   735  O  OG   . SER A 1 50  ? 54.02400  -36.62300 56.34200 1.000 82.41514  ? 50  SER A OG   1 
ATOM   736  H  H    . SER A 1 50  ? 55.31300  -37.21700 58.92100 1.000 99.82000  ? 50  SER A H    1 
ATOM   737  H  HA   . SER A 1 50  ? 55.52000  -34.67100 58.40600 1.000 97.53000  ? 50  SER A HA   1 
ATOM   738  H  HB2  . SER A 1 50  ? 55.40600  -35.23500 56.26100 1.000 99.72000  ? 50  SER A HB2  1 
ATOM   739  H  HB3  . SER A 1 50  ? 55.90400  -36.60200 56.89900 1.000 99.72000  ? 50  SER A HB3  1 
ATOM   740  H  HG   . SER A 1 50  ? 54.18500  -36.93300 55.57800 1.000 99.01000  ? 50  SER A HG   1 
ATOM   741  N  N    . HIS A 1 51  ? 52.59500  -35.51000 59.06700 1.000 76.14860  ? 51  HIS A N    1 
ATOM   742  C  CA   . HIS A 1 51  ? 51.21900  -35.04900 59.18000 1.000 71.49805  ? 51  HIS A CA   1 
ATOM   743  C  C    . HIS A 1 51  ? 51.03700  -33.96600 60.23600 1.000 70.81639  ? 51  HIS A C    1 
ATOM   744  O  O    . HIS A 1 51  ? 49.93600  -33.41600 60.34800 1.000 70.05840  ? 51  HIS A O    1 
ATOM   745  C  CB   . HIS A 1 51  ? 50.29900  -36.23000 59.50200 1.000 69.10829  ? 51  HIS A CB   1 
ATOM   746  C  CG   . HIS A 1 51  ? 50.09500  -37.16700 58.35200 1.000 72.00337  ? 51  HIS A CG   1 
ATOM   747  N  ND1  . HIS A 1 51  ? 49.34500  -38.31900 58.45400 1.000 72.13760  ? 51  HIS A ND1  1 
ATOM   748  C  CD2  . HIS A 1 51  ? 50.54300  -37.12200 57.07500 1.000 74.51157  ? 51  HIS A CD2  1 
ATOM   749  C  CE1  . HIS A 1 51  ? 49.33900  -38.94300 57.29000 1.000 77.55667  ? 51  HIS A CE1  1 
ATOM   750  N  NE2  . HIS A 1 51  ? 50.05900  -38.23800 56.43600 1.000 80.37016  ? 51  HIS A NE2  1 
ATOM   751  H  H    . HIS A 1 51  ? 52.76500  -36.22200 59.51900 1.000 91.49000  ? 51  HIS A H    1 
ATOM   752  H  HA   . HIS A 1 51  ? 50.94700  -34.67700 58.32600 1.000 85.91000  ? 51  HIS A HA   1 
ATOM   753  H  HB2  . HIS A 1 51  ? 50.68600  -36.73700 60.23200 1.000 83.04000  ? 51  HIS A HB2  1 
ATOM   754  H  HB3  . HIS A 1 51  ? 49.42900  -35.88700 59.76100 1.000 83.04000  ? 51  HIS A HB3  1 
ATOM   755  H  HD2  . HIS A 1 51  ? 51.07800  -36.46000 56.70100 1.000 89.53000  ? 51  HIS A HD2  1 
ATOM   756  H  HE1  . HIS A 1 51  ? 48.90300  -39.74300 57.10300 1.000 93.18000  ? 51  HIS A HE1  1 
ATOM   757  H  HE2  . HIS A 1 51  ? 50.20200  -38.44400 55.61300 1.000 96.56000  ? 51  HIS A HE2  1 
ATOM   758  N  N    . GLU A 1 52  ? 52.07700  -33.64300 61.00200 1.000 75.46957  ? 52  GLU A N    1 
ATOM   759  C  CA   . GLU A 1 52  ? 51.94000  -32.66100 62.07000 1.000 74.57736  ? 52  GLU A CA   1 
ATOM   760  C  C    . GLU A 1 52  ? 51.56100  -31.30000 61.50000 1.000 71.40856  ? 52  GLU A C    1 
ATOM   761  O  O    . GLU A 1 52  ? 52.14500  -30.83900 60.51500 1.000 74.87213  ? 52  GLU A O    1 
ATOM   762  C  CB   . GLU A 1 52  ? 53.24300  -32.55700 62.86200 1.000 77.96461  ? 52  GLU A CB   1 
ATOM   763  C  CG   . GLU A 1 52  ? 53.19400  -31.55300 64.00700 1.000 84.01007  ? 52  GLU A CG   1 
ATOM   764  C  CD   . GLU A 1 52  ? 53.67600  -32.13700 65.32100 1.000 89.12121  ? 52  GLU A CD   1 
ATOM   765  O  OE1  . GLU A 1 52  ? 54.82500  -32.62500 65.37100 1.000 96.10889  ? 52  GLU A OE1  1 
ATOM   766  O  OE2  . GLU A 1 52  ? 52.90600  -32.10500 66.30600 1.000 83.21787  ? 52  GLU A OE2  1 
ATOM   767  H  H    . GLU A 1 52  ? 52.86600  -33.97700 60.92400 1.000 90.68000  ? 52  GLU A H    1 
ATOM   768  H  HA   . GLU A 1 52  ? 51.23700  -32.94500 62.67500 1.000 89.61000  ? 52  GLU A HA   1 
ATOM   769  H  HB2  . GLU A 1 52  ? 53.44700  -33.42600 63.24100 1.000 93.67000  ? 52  GLU A HB2  1 
ATOM   770  H  HB3  . GLU A 1 52  ? 53.95300  -32.28300 62.26000 1.000 93.67000  ? 52  GLU A HB3  1 
ATOM   771  H  HG2  . GLU A 1 52  ? 53.76100  -30.79700 63.78800 1.000 100.93000 ? 52  GLU A HG2  1 
ATOM   772  H  HG3  . GLU A 1 52  ? 52.27800  -31.25700 64.12800 1.000 100.93000 ? 52  GLU A HG3  1 
ATOM   773  N  N    . GLY A 1 53  ? 50.57700  -30.65800 62.12600 1.000 66.96329  ? 53  GLY A N    1 
ATOM   774  C  CA   . GLY A 1 53  ? 50.13500  -29.34300 61.71900 1.000 63.71027  ? 53  GLY A CA   1 
ATOM   775  C  C    . GLY A 1 53  ? 49.24000  -29.30900 60.50100 1.000 64.52616  ? 53  GLY A C    1 
ATOM   776  O  O    . GLY A 1 53  ? 48.75100  -28.22900 60.14500 1.000 64.07874  ? 53  GLY A O    1 
ATOM   777  H  H    . GLY A 1 53  ? 50.14700  -30.97500 62.80100 1.000 80.47000  ? 53  GLY A H    1 
ATOM   778  H  HA2  . GLY A 1 53  ? 49.64600  -28.94000 62.45400 1.000 76.57000  ? 53  GLY A HA2  1 
ATOM   779  H  HA3  . GLY A 1 53  ? 50.91600  -28.80100 61.52500 1.000 76.57000  ? 53  GLY A HA3  1 
ATOM   780  N  N    . LYS A 1 54  ? 49.00400  -30.44600 59.85300 1.000 63.95504  ? 54  LYS A N    1 
ATOM   781  C  CA   . LYS A 1 54  ? 48.18700  -30.47400 58.65200 1.000 63.25758  ? 54  LYS A CA   1 
ATOM   782  C  C    . LYS A 1 54  ? 46.70400  -30.54000 59.00800 1.000 58.45175  ? 54  LYS A C    1 
ATOM   783  O  O    . LYS A 1 54  ? 46.31600  -30.93900 60.11100 1.000 55.58824  ? 54  LYS A O    1 
ATOM   784  C  CB   . LYS A 1 54  ? 48.57200  -31.66200 57.77000 1.000 61.78636  ? 54  LYS A CB   1 
ATOM   785  C  CG   . LYS A 1 54  ? 49.67100  -31.34600 56.76400 1.000 67.82655  ? 54  LYS A CG   1 
ATOM   786  C  CD   . LYS A 1 54  ? 50.29500  -32.61400 56.19700 1.000 73.86938  ? 54  LYS A CD   1 
ATOM   787  C  CE   . LYS A 1 54  ? 51.28900  -32.32200 55.07400 1.000 79.71482  ? 54  LYS A CE   1 
ATOM   788  N  NZ   . LYS A 1 54  ? 51.51400  -30.86800 54.83800 1.000 89.80024  ? 54  LYS A NZ   1 
ATOM   789  H  H    . LYS A 1 54  ? 49.30800  -31.21500 60.09100 1.000 76.86000  ? 54  LYS A H    1 
ATOM   790  H  HA   . LYS A 1 54  ? 48.33600  -29.66100 58.14400 1.000 76.02000  ? 54  LYS A HA   1 
ATOM   791  H  HB2  . LYS A 1 54  ? 48.88700  -32.38300 58.33700 1.000 74.26000  ? 54  LYS A HB2  1 
ATOM   792  H  HB3  . LYS A 1 54  ? 47.78900  -31.94900 57.27400 1.000 74.26000  ? 54  LYS A HB3  1 
ATOM   793  H  HG2  . LYS A 1 54  ? 49.29600  -30.83600 56.02900 1.000 81.50000  ? 54  LYS A HG2  1 
ATOM   794  H  HG3  . LYS A 1 54  ? 50.36800  -30.83300 57.20200 1.000 81.50000  ? 54  LYS A HG3  1 
ATOM   795  H  HD2  . LYS A 1 54  ? 50.76800  -33.07900 56.90400 1.000 88.76000  ? 54  LYS A HD2  1 
ATOM   796  H  HD3  . LYS A 1 54  ? 49.59400  -33.18000 55.83900 1.000 88.76000  ? 54  LYS A HD3  1 
ATOM   797  H  HE2  . LYS A 1 54  ? 52.14300  -32.72100 55.30100 1.000 95.77000  ? 54  LYS A HE2  1 
ATOM   798  H  HE3  . LYS A 1 54  ? 50.95100  -32.70700 54.25000 1.000 95.77000  ? 54  LYS A HE3  1 
ATOM   799  H  HZ1  . LYS A 1 54  ? 50.76200  -30.48600 54.55200 1.000 107.87000 ? 54  LYS A HZ1  1 
ATOM   800  H  HZ2  . LYS A 1 54  ? 51.77000  -30.47200 55.59300 1.000 107.87000 ? 54  LYS A HZ2  1 
ATOM   801  H  HZ3  . LYS A 1 54  ? 52.14700  -30.75400 54.22300 1.000 107.87000 ? 54  LYS A HZ3  1 
ATOM   802  N  N    . THR A 1 55  ? 45.87400  -30.13900 58.04900 1.000 53.21428  ? 55  THR A N    1 
ATOM   803  C  CA   . THR A 1 55  ? 44.42800  -30.08400 58.21800 1.000 52.78791  ? 55  THR A CA   1 
ATOM   804  C  C    . THR A 1 55  ? 43.79600  -31.34000 57.63100 1.000 50.09811  ? 55  THR A C    1 
ATOM   805  O  O    . THR A 1 55  ? 44.14000  -31.75400 56.51900 1.000 55.26715  ? 55  THR A O    1 
ATOM   806  C  CB   . THR A 1 55  ? 43.85200  -28.83700 57.54300 1.000 53.71170  ? 55  THR A CB   1 
ATOM   807  O  OG1  . THR A 1 55  ? 44.45500  -27.66300 58.10400 1.000 57.93063  ? 55  THR A OG1  1 
ATOM   808  C  CG2  . THR A 1 55  ? 42.34000  -28.76700 57.72700 1.000 50.50869  ? 55  THR A CG2  1 
ATOM   809  H  H    . THR A 1 55  ? 46.13400  -29.88500 57.26900 1.000 63.97000  ? 55  THR A H    1 
ATOM   810  H  HA   . THR A 1 55  ? 44.21400  -30.04900 59.16300 1.000 63.46000  ? 55  THR A HA   1 
ATOM   811  H  HB   . THR A 1 55  ? 44.03800  -28.87400 56.59100 1.000 64.57000  ? 55  THR A HB   1 
ATOM   812  H  HG1  . THR A 1 55  ? 44.28700  -27.61800 58.92500 1.000 69.63000  ? 55  THR A HG1  1 
ATOM   813  H  HG21 . THR A 1 55  ? 42.01500  -27.89000 57.46900 1.000 60.73000  ? 55  THR A HG21 1 
ATOM   814  H  HG22 . THR A 1 55  ? 41.90800  -29.43800 57.17600 1.000 60.73000  ? 55  THR A HG22 1 
ATOM   815  H  HG23 . THR A 1 55  ? 42.11200  -28.92600 58.65600 1.000 60.73000  ? 55  THR A HG23 1 
ATOM   816  N  N    . PHE A 1 56  ? 42.87200  -31.93900 58.38000 1.000 52.70895  ? 56  PHE A N    1 
ATOM   817  C  CA   . PHE A 1 56  ? 42.17300  -33.14600 57.96600 1.000 48.33211  ? 56  PHE A CA   1 
ATOM   818  C  C    . PHE A 1 56  ? 40.67000  -32.90500 57.97900 1.000 51.25878  ? 56  PHE A C    1 
ATOM   819  O  O    . PHE A 1 56  ? 40.14000  -32.27500 58.90100 1.000 51.77200  ? 56  PHE A O    1 
ATOM   820  C  CB   . PHE A 1 56  ? 42.50300  -34.32600 58.88800 1.000 48.53740  ? 56  PHE A CB   1 
ATOM   821  C  CG   . PHE A 1 56  ? 43.93300  -34.77300 58.81800 1.000 54.51180  ? 56  PHE A CG   1 
ATOM   822  C  CD1  . PHE A 1 56  ? 44.91400  -34.11800 59.54300 1.000 56.14621  ? 56  PHE A CD1  1 
ATOM   823  C  CD2  . PHE A 1 56  ? 44.29700  -35.85600 58.03500 1.000 57.42267  ? 56  PHE A CD2  1 
ATOM   824  C  CE1  . PHE A 1 56  ? 46.23100  -34.52900 59.48500 1.000 57.08842  ? 56  PHE A CE1  1 
ATOM   825  C  CE2  . PHE A 1 56  ? 45.61400  -36.27300 57.97200 1.000 59.13867  ? 56  PHE A CE2  1 
ATOM   826  C  CZ   . PHE A 1 56  ? 46.58100  -35.60800 58.69800 1.000 59.82296  ? 56  PHE A CZ   1 
ATOM   827  H  H    . PHE A 1 56  ? 42.62800  -31.65300 59.15400 1.000 63.36000  ? 56  PHE A H    1 
ATOM   828  H  HA   . PHE A 1 56  ? 42.44200  -33.37300 57.06200 1.000 58.11000  ? 56  PHE A HA   1 
ATOM   829  H  HB2  . PHE A 1 56  ? 42.32000  -34.06600 59.80400 1.000 58.36000  ? 56  PHE A HB2  1 
ATOM   830  H  HB3  . PHE A 1 56  ? 41.94600  -35.08000 58.63900 1.000 58.36000  ? 56  PHE A HB3  1 
ATOM   831  H  HD1  . PHE A 1 56  ? 44.68300  -33.39200 60.07700 1.000 67.49000  ? 56  PHE A HD1  1 
ATOM   832  H  HD2  . PHE A 1 56  ? 43.64800  -36.30800 57.54500 1.000 69.02000  ? 56  PHE A HD2  1 
ATOM   833  H  HE1  . PHE A 1 56  ? 46.88200  -34.08000 59.97400 1.000 68.62000  ? 56  PHE A HE1  1 
ATOM   834  H  HE2  . PHE A 1 56  ? 45.84700  -37.00000 57.44200 1.000 71.08000  ? 56  PHE A HE2  1 
ATOM   835  H  HZ   . PHE A 1 56  ? 47.46800  -35.88700 58.65800 1.000 71.90000  ? 56  PHE A HZ   1 
ATOM   836  N  N    . TYR A 1 57  ? 39.98700  -33.41400 56.95600 1.000 52.08519  ? 57  TYR A N    1 
ATOM   837  C  CA   . TYR A 1 57  ? 38.53200  -33.38600 56.92400 1.000 46.31345  ? 57  TYR A CA   1 
ATOM   838  C  C    . TYR A 1 57  ? 37.97100  -34.54200 57.74100 1.000 49.33749  ? 57  TYR A C    1 
ATOM   839  O  O    . TYR A 1 57  ? 38.49400  -35.66000 57.70000 1.000 54.59339  ? 57  TYR A O    1 
ATOM   840  C  CB   . TYR A 1 57  ? 38.02500  -33.48400 55.48600 1.000 50.45342  ? 57  TYR A CB   1 
ATOM   841  C  CG   . TYR A 1 57  ? 38.03100  -32.18400 54.71600 1.000 48.25842  ? 57  TYR A CG   1 
ATOM   842  C  CD1  . TYR A 1 57  ? 39.22100  -31.61300 54.28300 1.000 51.50091  ? 57  TYR A CD1  1 
ATOM   843  C  CD2  . TYR A 1 57  ? 36.84300  -31.53900 54.40400 1.000 46.93457  ? 57  TYR A CD2  1 
ATOM   844  C  CE1  . TYR A 1 57  ? 39.22600  -30.42900 53.57000 1.000 50.41131  ? 57  TYR A CE1  1 
ATOM   845  C  CE2  . TYR A 1 57  ? 36.83700  -30.35800 53.69300 1.000 51.95886  ? 57  TYR A CE2  1 
ATOM   846  C  CZ   . TYR A 1 57  ? 38.03000  -29.80800 53.27700 1.000 53.60906  ? 57  TYR A CZ   1 
ATOM   847  O  OH   . TYR A 1 57  ? 38.02100  -28.63300 52.56400 1.000 53.51957  ? 57  TYR A OH   1 
ATOM   848  H  H    . TYR A 1 57  ? 40.34700  -33.78200 56.26700 1.000 62.61000  ? 57  TYR A H    1 
ATOM   849  H  HA   . TYR A 1 57  ? 38.21700  -32.54900 57.30000 1.000 55.69000  ? 57  TYR A HA   1 
ATOM   850  H  HB2  . TYR A 1 57  ? 38.58800  -34.10900 55.00400 1.000 60.66000  ? 57  TYR A HB2  1 
ATOM   851  H  HB3  . TYR A 1 57  ? 37.11100  -33.80700 55.50500 1.000 60.66000  ? 57  TYR A HB3  1 
ATOM   852  H  HD1  . TYR A 1 57  ? 40.02700  -32.03400 54.47700 1.000 61.91000  ? 57  TYR A HD1  1 
ATOM   853  H  HD2  . TYR A 1 57  ? 36.03600  -31.90900 54.68000 1.000 56.44000  ? 57  TYR A HD2  1 
ATOM   854  H  HE1  . TYR A 1 57  ? 40.03000  -30.05500 53.28900 1.000 60.61000  ? 57  TYR A HE1  1 
ATOM   855  H  HE2  . TYR A 1 57  ? 36.03300  -29.93500 53.49500 1.000 62.47000  ? 57  TYR A HE2  1 
ATOM   856  H  HH   . TYR A 1 57  ? 37.23200  -28.36200 52.46700 1.000 64.34000  ? 57  TYR A HH   1 
ATOM   857  N  N    . VAL A 1 58  ? 36.89600  -34.27200 58.48300 1.000 48.16367  ? 58  VAL A N    1 
ATOM   858  C  CA   . VAL A 1 58  ? 36.22800  -35.28300 59.29100 1.000 51.35879  ? 58  VAL A CA   1 
ATOM   859  C  C    . VAL A 1 58  ? 34.72200  -35.11400 59.14600 1.000 50.78504  ? 58  VAL A C    1 
ATOM   860  O  O    . VAL A 1 58  ? 34.22800  -34.06700 58.72600 1.000 50.51922  ? 58  VAL A O    1 
ATOM   861  C  CB   . VAL A 1 58  ? 36.62900  -35.20300 60.78200 1.000 51.11666  ? 58  VAL A CB   1 
ATOM   862  C  CG1  . VAL A 1 58  ? 38.11900  -35.46500 60.94800 1.000 51.30615  ? 58  VAL A CG1  1 
ATOM   863  C  CG2  . VAL A 1 58  ? 36.25200  -33.84800 61.36300 1.000 51.14034  ? 58  VAL A CG2  1 
ATOM   864  H  H    . VAL A 1 58  ? 36.53000  -33.49500 58.53200 1.000 57.91000  ? 58  VAL A H    1 
ATOM   865  H  HA   . VAL A 1 58  ? 36.46900  -36.16200 58.95900 1.000 61.74000  ? 58  VAL A HA   1 
ATOM   866  H  HB   . VAL A 1 58  ? 36.14700  -35.88600 61.27400 1.000 61.45000  ? 58  VAL A HB   1 
ATOM   867  H  HG11 . VAL A 1 58  ? 38.34000  -35.44400 61.89300 1.000 61.68000  ? 58  VAL A HG11 1 
ATOM   868  H  HG12 . VAL A 1 58  ? 38.32900  -36.33700 60.57900 1.000 61.68000  ? 58  VAL A HG12 1 
ATOM   869  H  HG13 . VAL A 1 58  ? 38.61600  -34.77800 60.47700 1.000 61.68000  ? 58  VAL A HG13 1 
ATOM   870  H  HG21 . VAL A 1 58  ? 36.64800  -33.76100 62.24500 1.000 61.48000  ? 58  VAL A HG21 1 
ATOM   871  H  HG22 . VAL A 1 58  ? 36.58700  -33.15000 60.78000 1.000 61.48000  ? 58  VAL A HG22 1 
ATOM   872  H  HG23 . VAL A 1 58  ? 35.28600  -33.79000 61.42800 1.000 61.48000  ? 58  VAL A HG23 1 
ATOM   873  N  N    . LEU A 1 59  ? 33.99100  -36.17000 59.50300 1.000 56.61731  ? 59  LEU A N    1 
ATOM   874  C  CA   . LEU A 1 59  ? 32.53600  -36.09900 59.46600 1.000 59.39923  ? 59  LEU A CA   1 
ATOM   875  C  C    . LEU A 1 59  ? 32.02000  -35.28900 60.65300 1.000 60.62306  ? 59  LEU A C    1 
ATOM   876  O  O    . LEU A 1 59  ? 32.59000  -35.35700 61.74500 1.000 62.47065  ? 59  LEU A O    1 
ATOM   877  C  CB   . LEU A 1 59  ? 31.92600  -37.49700 59.49900 1.000 60.38356  ? 59  LEU A CB   1 
ATOM   878  C  CG   . LEU A 1 59  ? 31.41800  -38.02600 58.16000 1.000 65.98686  ? 59  LEU A CG   1 
ATOM   879  C  CD1  . LEU A 1 59  ? 32.58400  -38.52900 57.33800 1.000 66.87907  ? 59  LEU A CD1  1 
ATOM   880  C  CD2  . LEU A 1 59  ? 30.39000  -39.12300 58.37200 1.000 73.26142  ? 59  LEU A CD2  1 
ATOM   881  H  H    . LEU A 1 59  ? 34.30900  -36.92400 59.76700 1.000 68.05000  ? 59  LEU A H    1 
ATOM   882  H  HA   . LEU A 1 59  ? 32.25600  -35.66500 58.64500 1.000 71.39000  ? 59  LEU A HA   1 
ATOM   883  H  HB2  . LEU A 1 59  ? 32.60100  -38.11600 59.81800 1.000 72.57000  ? 59  LEU A HB2  1 
ATOM   884  H  HB3  . LEU A 1 59  ? 31.17200  -37.48500 60.11000 1.000 72.57000  ? 59  LEU A HB3  1 
ATOM   885  H  HG   . LEU A 1 59  ? 30.98200  -37.31000 57.67100 1.000 79.30000  ? 59  LEU A HG   1 
ATOM   886  H  HD11 . LEU A 1 59  ? 32.25200  -38.86200 56.49000 1.000 80.37000  ? 59  LEU A HD11 1 
ATOM   887  H  HD12 . LEU A 1 59  ? 33.20200  -37.79700 57.18600 1.000 80.37000  ? 59  LEU A HD12 1 
ATOM   888  H  HD13 . LEU A 1 59  ? 33.02800  -39.24200 57.82300 1.000 80.37000  ? 59  LEU A HD13 1 
ATOM   889  H  HD21 . LEU A 1 59  ? 30.08500  -39.44100 57.50800 1.000 88.03000  ? 59  LEU A HD21 1 
ATOM   890  H  HD22 . LEU A 1 59  ? 30.80100  -39.85000 58.86500 1.000 88.03000  ? 59  LEU A HD22 1 
ATOM   891  H  HD23 . LEU A 1 59  ? 29.64300  -38.76300 58.87500 1.000 88.03000  ? 59  LEU A HD23 1 
ATOM   892  N  N    . PRO A 1 60  ? 30.94500  -34.51500 60.47400 1.000 64.97884  ? 60  PRO A N    1 
ATOM   893  C  CA   . PRO A 1 60  ? 30.38200  -33.78000 61.61500 1.000 66.04213  ? 60  PRO A CA   1 
ATOM   894  C  C    . PRO A 1 60  ? 29.92600  -34.71600 62.72400 1.000 73.24826  ? 60  PRO A C    1 
ATOM   895  O  O    . PRO A 1 60  ? 28.84000  -35.30100 62.64700 1.000 79.02526  ? 60  PRO A O    1 
ATOM   896  C  CB   . PRO A 1 60  ? 29.20500  -33.01000 61.00000 1.000 65.12886  ? 60  PRO A CB   1 
ATOM   897  C  CG   . PRO A 1 60  ? 29.47200  -32.97800 59.53400 1.000 69.33726  ? 60  PRO A CG   1 
ATOM   898  C  CD   . PRO A 1 60  ? 30.23000  -34.22700 59.21800 1.000 68.01605  ? 60  PRO A CD   1 
ATOM   899  H  HA   . PRO A 1 60  ? 31.02500  -33.14400 61.96600 1.000 79.37000  ? 60  PRO A HA   1 
ATOM   900  H  HB2  . PRO A 1 60  ? 28.37400  -33.47400 61.19000 1.000 78.27000  ? 60  PRO A HB2  1 
ATOM   901  H  HB3  . PRO A 1 60  ? 29.17300  -32.11200 61.36500 1.000 78.27000  ? 60  PRO A HB3  1 
ATOM   902  H  HG2  . PRO A 1 60  ? 28.63200  -32.95700 59.05100 1.000 83.32000  ? 60  PRO A HG2  1 
ATOM   903  H  HG3  . PRO A 1 60  ? 30.00000  -32.19400 59.31700 1.000 83.32000  ? 60  PRO A HG3  1 
ATOM   904  H  HD2  . PRO A 1 60  ? 29.62500  -34.95000 58.99100 1.000 81.73000  ? 60  PRO A HD2  1 
ATOM   905  H  HD3  . PRO A 1 60  ? 30.85500  -34.07700 58.49100 1.000 81.73000  ? 60  PRO A HD3  1 
ATOM   906  N  N    . ASN A 1 61  ? 30.75200  -34.86800 63.75800 1.000 71.54805  ? 61  ASN A N    1 
ATOM   907  C  CA   . ASN A 1 61  ? 30.46500  -35.77000 64.86600 1.000 77.65405  ? 61  ASN A CA   1 
ATOM   908  C  C    . ASN A 1 61  ? 30.13900  -35.02900 66.15900 1.000 78.67259  ? 61  ASN A C    1 
ATOM   909  O  O    . ASN A 1 61  ? 30.04100  -35.66200 67.21600 1.000 83.05206  ? 61  ASN A O    1 
ATOM   910  C  CB   . ASN A 1 61  ? 31.64500  -36.72400 65.08500 1.000 83.32315  ? 61  ASN A CB   1 
ATOM   911  C  CG   . ASN A 1 61  ? 32.86300  -36.03000 65.67100 1.000 84.63646  ? 61  ASN A CG   1 
ATOM   912  O  OD1  . ASN A 1 61  ? 32.82100  -35.50400 66.78400 1.000 88.03687  ? 61  ASN A OD1  1 
ATOM   913  N  ND2  . ASN A 1 61  ? 33.96000  -36.03100 64.92200 1.000 84.81543  ? 61  ASN A ND2  1 
ATOM   914  H  H    . ASN A 1 61  ? 31.50000  -34.45100 63.84000 1.000 85.97000  ? 61  ASN A H    1 
ATOM   915  H  HA   . ASN A 1 61  ? 29.68800  -36.30300 64.63500 1.000 93.30000  ? 61  ASN A HA   1 
ATOM   916  H  HB2  . ASN A 1 61  ? 31.37500  -37.42400 65.69900 1.000 100.10000 ? 61  ASN A HB2  1 
ATOM   917  H  HB3  . ASN A 1 61  ? 31.90100  -37.11000 64.23300 1.000 100.10000 ? 61  ASN A HB3  1 
ATOM   918  H  HD21 . ASN A 1 61  ? 33.95400  -36.41200 64.15100 1.000 101.89000 ? 61  ASN A HD21 1 
ATOM   919  H  HD22 . ASN A 1 61  ? 34.67700  -35.65200 65.20900 1.000 101.89000 ? 61  ASN A HD22 1 
ATOM   920  N  N    . ASP A 1 62  ? 29.97500  -33.70900 66.10500 1.000 75.10111  ? 62  ASP A N    1 
ATOM   921  C  CA   . ASP A 1 62  ? 29.55300  -32.94100 67.26800 1.000 71.66386  ? 62  ASP A CA   1 
ATOM   922  C  C    . ASP A 1 62  ? 28.75200  -31.73900 66.78900 1.000 65.29993  ? 62  ASP A C    1 
ATOM   923  O  O    . ASP A 1 62  ? 28.79200  -31.37000 65.61200 1.000 68.83720  ? 62  ASP A O    1 
ATOM   924  C  CB   . ASP A 1 62  ? 30.74900  -32.50800 68.13200 1.000 71.17169  ? 62  ASP A CB   1 
ATOM   925  C  CG   . ASP A 1 62  ? 31.69200  -31.55100 67.41600 1.000 72.57712  ? 62  ASP A CG   1 
ATOM   926  O  OD1  . ASP A 1 62  ? 31.22200  -30.67900 66.65400 1.000 70.88218  ? 62  ASP A OD1  1 
ATOM   927  O  OD2  . ASP A 1 62  ? 32.91800  -31.66800 67.62600 1.000 73.28510  ? 62  ASP A OD2  1 
ATOM   928  H  H    . ASP A 1 62  ? 30.10400  -33.23400 65.40000 1.000 90.23000  ? 62  ASP A H    1 
ATOM   929  H  HA   . ASP A 1 62  ? 28.97400  -33.48300 67.82600 1.000 86.11000  ? 62  ASP A HA   1 
ATOM   930  H  HB2  . ASP A 1 62  ? 30.41700  -32.06200 68.92700 1.000 85.52000  ? 62  ASP A HB2  1 
ATOM   931  H  HB3  . ASP A 1 62  ? 31.25700  -33.29600 68.38200 1.000 85.52000  ? 62  ASP A HB3  1 
ATOM   932  N  N    . ASP A 1 63  ? 28.01700  -31.13000 67.72200 1.000 64.04715  ? 63  ASP A N    1 
ATOM   933  C  CA   . ASP A 1 63  ? 27.12000  -30.03700 67.35800 1.000 67.67917  ? 63  ASP A CA   1 
ATOM   934  C  C    . ASP A 1 63  ? 27.86700  -28.91500 66.64700 1.000 63.78133  ? 63  ASP A C    1 
ATOM   935  O  O    . ASP A 1 63  ? 27.36500  -28.34600 65.67100 1.000 58.32015  ? 63  ASP A O    1 
ATOM   936  C  CB   . ASP A 1 63  ? 26.41400  -29.50300 68.60400 1.000 63.83397  ? 63  ASP A CB   1 
ATOM   937  C  CG   . ASP A 1 63  ? 25.25300  -30.37900 69.03800 1.000 66.88697  ? 63  ASP A CG   1 
ATOM   938  O  OD1  . ASP A 1 63  ? 24.95600  -31.37100 68.33800 1.000 61.87058  ? 63  ASP A OD1  1 
ATOM   939  O  OD2  . ASP A 1 63  ? 24.63500  -30.07600 70.08000 1.000 71.25328  ? 63  ASP A OD2  1 
ATOM   940  H  H    . ASP A 1 63  ? 28.02000  -31.32800 68.55900 1.000 76.97000  ? 63  ASP A H    1 
ATOM   941  H  HA   . ASP A 1 63  ? 26.44600  -30.37900 66.74900 1.000 81.33000  ? 63  ASP A HA   1 
ATOM   942  H  HB2  . ASP A 1 63  ? 27.05000  -29.46200 69.33600 1.000 76.71000  ? 63  ASP A HB2  1 
ATOM   943  H  HB3  . ASP A 1 63  ? 26.06700  -28.61600 68.41600 1.000 76.71000  ? 63  ASP A HB3  1 
ATOM   944  N  N    . THR A 1 64  ? 29.07000  -28.58200 67.12000 1.000 61.87847  ? 64  THR A N    1 
ATOM   945  C  CA   . THR A 1 64  ? 29.82700  -27.49300 66.51000 1.000 56.04093  ? 64  THR A CA   1 
ATOM   946  C  C    . THR A 1 64  ? 30.14500  -27.79700 65.05100 1.000 58.67809  ? 64  THR A C    1 
ATOM   947  O  O    . THR A 1 64  ? 29.98600  -26.93800 64.17500 1.000 54.68550  ? 64  THR A O    1 
ATOM   948  C  CB   . THR A 1 64  ? 31.11300  -27.24300 67.29900 1.000 55.45665  ? 64  THR A CB   1 
ATOM   949  O  OG1  . THR A 1 64  ? 30.78900  -26.86200 68.64200 1.000 67.72917  ? 64  THR A OG1  1 
ATOM   950  C  CG2  . THR A 1 64  ? 31.93700  -26.14300 66.64300 1.000 49.50594  ? 64  THR A CG2  1 
ATOM   951  H  H    . THR A 1 64  ? 29.46300  -28.96600 67.78100 1.000 74.37000  ? 64  THR A H    1 
ATOM   952  H  HA   . THR A 1 64  ? 29.29100  -26.68500 66.54200 1.000 67.36000  ? 64  THR A HA   1 
ATOM   953  H  HB   . THR A 1 64  ? 31.64500  -28.05400 67.31500 1.000 66.66000  ? 64  THR A HB   1 
ATOM   954  H  HG1  . THR A 1 64  ? 31.49400  -26.72800 69.08000 1.000 81.39000  ? 64  THR A HG1  1 
ATOM   955  H  HG21 . THR A 1 64  ? 32.61600  -25.82600 67.25900 1.000 59.52000  ? 64  THR A HG21 1 
ATOM   956  H  HG22 . THR A 1 64  ? 32.37000  -26.48400 65.84500 1.000 59.52000  ? 64  THR A HG22 1 
ATOM   957  H  HG23 . THR A 1 64  ? 31.36300  -25.40100 66.39700 1.000 59.52000  ? 64  THR A HG23 1 
ATOM   958  N  N    . LEU A 1 65  ? 30.60100  -29.01800 64.77000 1.000 60.22564  ? 65  LEU A N    1 
ATOM   959  C  CA   . LEU A 1 65  ? 30.92000  -29.38300 63.39400 1.000 55.80932  ? 65  LEU A CA   1 
ATOM   960  C  C    . LEU A 1 65  ? 29.66200  -29.45700 62.53700 1.000 54.37231  ? 65  LEU A C    1 
ATOM   961  O  O    . LEU A 1 65  ? 29.68100  -29.06900 61.36300 1.000 51.71673  ? 65  LEU A O    1 
ATOM   962  C  CB   . LEU A 1 65  ? 31.67100  -30.71300 63.36500 1.000 54.57233  ? 65  LEU A CB   1 
ATOM   963  C  CG   . LEU A 1 65  ? 33.09700  -30.68700 63.92400 1.000 57.10422  ? 65  LEU A CG   1 
ATOM   964  C  CD1  . LEU A 1 65  ? 33.66600  -32.09500 64.01400 1.000 58.15434  ? 65  LEU A CD1  1 
ATOM   965  C  CD2  . LEU A 1 65  ? 34.00200  -29.80300 63.07800 1.000 53.72749  ? 65  LEU A CD2  1 
ATOM   966  H  H    . LEU A 1 65  ? 30.73200  -29.64200 65.34800 1.000 72.38000  ? 65  LEU A H    1 
ATOM   967  H  HA   . LEU A 1 65  ? 31.50000  -28.70300 63.01600 1.000 67.09000  ? 65  LEU A HA   1 
ATOM   968  H  HB2  . LEU A 1 65  ? 31.16900  -31.35600 63.89000 1.000 65.60000  ? 65  LEU A HB2  1 
ATOM   969  H  HB3  . LEU A 1 65  ? 31.72900  -31.00900 62.44300 1.000 65.60000  ? 65  LEU A HB3  1 
ATOM   970  H  HG   . LEU A 1 65  ? 33.06800  -30.31300 64.81800 1.000 68.64000  ? 65  LEU A HG   1 
ATOM   971  H  HD11 . LEU A 1 65  ? 34.56600  -32.05000 64.37300 1.000 69.90000  ? 65  LEU A HD11 1 
ATOM   972  H  HD12 . LEU A 1 65  ? 33.10300  -32.62600 64.59900 1.000 69.90000  ? 65  LEU A HD12 1 
ATOM   973  H  HD13 . LEU A 1 65  ? 33.68200  -32.48700 63.12700 1.000 69.90000  ? 65  LEU A HD13 1 
ATOM   974  H  HD21 . LEU A 1 65  ? 34.92100  -29.92800 63.36200 1.000 64.59000  ? 65  LEU A HD21 1 
ATOM   975  H  HD22 . LEU A 1 65  ? 33.90600  -30.05300 62.14600 1.000 64.59000  ? 65  LEU A HD22 1 
ATOM   976  H  HD23 . LEU A 1 65  ? 33.74100  -28.87600 63.20000 1.000 64.59000  ? 65  LEU A HD23 1 
ATOM   977  N  N    . ARG A 1 66  ? 28.55800  -29.95300 63.10300 1.000 53.99068  ? 66  ARG A N    1 
ATOM   978  C  CA   . ARG A 1 66  ? 27.31000  -30.01300 62.34800 1.000 54.51969  ? 66  ARG A CA   1 
ATOM   979  C  C    . ARG A 1 66  ? 26.89100  -28.62700 61.87200 1.000 52.16152  ? 66  ARG A C    1 
ATOM   980  O  O    . ARG A 1 66  ? 26.49200  -28.45500 60.71400 1.000 52.00097  ? 66  ARG A O    1 
ATOM   981  C  CB   . ARG A 1 66  ? 26.20500  -30.64100 63.20000 1.000 56.35676  ? 66  ARG A CB   1 
ATOM   982  C  CG   . ARG A 1 66  ? 26.39100  -32.13000 63.46800 1.000 67.52652  ? 66  ARG A CG   1 
ATOM   983  C  CD   . ARG A 1 66  ? 25.20100  -32.72500 64.21700 1.000 73.67462  ? 66  ARG A CD   1 
ATOM   984  N  NE   . ARG A 1 66  ? 25.47100  -34.07600 64.70000 1.000 77.37770  ? 66  ARG A NE   1 
ATOM   985  C  CZ   . ARG A 1 66  ? 25.97400  -34.36700 65.89400 1.000 80.85706  ? 66  ARG A CZ   1 
ATOM   986  N  NH1  . ARG A 1 66  ? 26.26600  -33.42200 66.77300 1.000 75.57748  ? 66  ARG A NH1  1 
ATOM   987  N  NH2  . ARG A 1 66  ? 26.18800  -35.64100 66.21400 1.000 83.31788  ? 66  ARG A NH2  1 
ATOM   988  H  H    . ARG A 1 66  ? 28.50800  -30.25500 63.90700 1.000 64.90000  ? 66  ARG A H    1 
ATOM   989  H  HA   . ARG A 1 66  ? 27.44400  -30.57600 61.57000 1.000 65.54000  ? 66  ARG A HA   1 
ATOM   990  H  HB2  . ARG A 1 66  ? 26.18000  -30.18900 64.05800 1.000 67.74000  ? 66  ARG A HB2  1 
ATOM   991  H  HB3  . ARG A 1 66  ? 25.35800  -30.52900 62.74100 1.000 67.74000  ? 66  ARG A HB3  1 
ATOM   992  H  HG2  . ARG A 1 66  ? 26.48300  -32.59800 62.62400 1.000 81.15000  ? 66  ARG A HG2  1 
ATOM   993  H  HG3  . ARG A 1 66  ? 27.18600  -32.26100 64.00900 1.000 81.15000  ? 66  ARG A HG3  1 
ATOM   994  H  HD2  . ARG A 1 66  ? 24.99500  -32.16600 64.98300 1.000 88.52000  ? 66  ARG A HD2  1 
ATOM   995  H  HD3  . ARG A 1 66  ? 24.43700  -32.76500 63.62100 1.000 88.52000  ? 66  ARG A HD3  1 
ATOM   996  H  HE   . ARG A 1 66  ? 25.29200  -34.73100 64.17300 1.000 92.97000  ? 66  ARG A HE   1 
ATOM   997  H  HH11 . ARG A 1 66  ? 26.13100  -32.59600 66.57700 1.000 90.81000  ? 66  ARG A HH11 1 
ATOM   998  H  HH12 . ARG A 1 66  ? 26.59100  -33.63500 67.54100 1.000 90.81000  ? 66  ARG A HH12 1 
ATOM   999  H  HH21 . ARG A 1 66  ? 26.00000  -36.26300 65.65100 1.000 100.10000 ? 66  ARG A HH21 1 
ATOM   1000 H  HH22 . ARG A 1 66  ? 26.51300  -35.84100 66.98500 1.000 100.10000 ? 66  ARG A HH22 1 
ATOM   1001 N  N    . VAL A 1 67  ? 26.98000  -27.62500 62.74800 1.000 52.15625  ? 67  VAL A N    1 
ATOM   1002 C  CA   . VAL A 1 67  ? 26.57300  -26.27300 62.37400 1.000 50.42710  ? 67  VAL A CA   1 
ATOM   1003 C  C    . VAL A 1 67  ? 27.52200  -25.70200 61.32700 1.000 53.88541  ? 67  VAL A C    1 
ATOM   1004 O  O    . VAL A 1 67  ? 27.09100  -25.10800 60.33100 1.000 49.16642  ? 67  VAL A O    1 
ATOM   1005 C  CB   . VAL A 1 67  ? 26.50200  -25.37100 63.61900 1.000 55.34085  ? 67  VAL A CB   1 
ATOM   1006 C  CG1  . VAL A 1 67  ? 26.30700  -23.91800 63.20900 1.000 51.97202  ? 67  VAL A CG1  1 
ATOM   1007 C  CG2  . VAL A 1 67  ? 25.38300  -25.82800 64.54500 1.000 56.34097  ? 67  VAL A CG2  1 
ATOM   1008 H  H    . VAL A 1 67  ? 27.26900  -27.70100 63.55500 1.000 62.70000  ? 67  VAL A H    1 
ATOM   1009 H  HA   . VAL A 1 67  ? 25.68700  -26.31700 61.98300 1.000 60.62000  ? 67  VAL A HA   1 
ATOM   1010 H  HB   . VAL A 1 67  ? 27.33900  -25.43700 64.10500 1.000 66.52000  ? 67  VAL A HB   1 
ATOM   1011 H  HG11 . VAL A 1 67  ? 25.98700  -23.41400 63.97400 1.000 62.48000  ? 67  VAL A HG11 1 
ATOM   1012 H  HG12 . VAL A 1 67  ? 27.15600  -23.55800 62.90700 1.000 62.48000  ? 67  VAL A HG12 1 
ATOM   1013 H  HG13 . VAL A 1 67  ? 25.65700  -23.87700 62.49100 1.000 62.48000  ? 67  VAL A HG13 1 
ATOM   1014 H  HG21 . VAL A 1 67  ? 25.35900  -25.24700 65.32100 1.000 67.72000  ? 67  VAL A HG21 1 
ATOM   1015 H  HG22 . VAL A 1 67  ? 24.53900  -25.77800 64.06900 1.000 67.72000  ? 67  VAL A HG22 1 
ATOM   1016 H  HG23 . VAL A 1 67  ? 25.55400  -26.74200 64.82000 1.000 67.72000  ? 67  VAL A HG23 1 
ATOM   1017 N  N    . GLU A 1 68  ? 28.83000  -25.86300 61.53900 1.000 50.00336  ? 68  GLU A N    1 
ATOM   1018 C  CA   . GLU A 1 68  ? 29.79700  -25.35100 60.57500 1.000 50.43499  ? 68  GLU A CA   1 
ATOM   1019 C  C    . GLU A 1 68  ? 29.60200  -25.99300 59.20800 1.000 51.94833  ? 68  GLU A C    1 
ATOM   1020 O  O    . GLU A 1 68  ? 29.71500  -25.32000 58.17600 1.000 49.71912  ? 68  GLU A O    1 
ATOM   1021 C  CB   . GLU A 1 68  ? 31.21900  -25.58900 61.08500 1.000 51.69304  ? 68  GLU A CB   1 
ATOM   1022 C  CG   . GLU A 1 68  ? 31.61100  -24.68300 62.24300 1.000 52.92477  ? 68  GLU A CG   1 
ATOM   1023 C  CD   . GLU A 1 68  ? 32.94100  -25.06200 62.86500 1.000 54.70130  ? 68  GLU A CD   1 
ATOM   1024 O  OE1  . GLU A 1 68  ? 33.54100  -26.06500 62.42600 1.000 52.78264  ? 68  GLU A OE1  1 
ATOM   1025 O  OE2  . GLU A 1 68  ? 33.38600  -24.35700 63.79600 1.000 55.73037  ? 68  GLU A OE2  1 
ATOM   1026 H  H    . GLU A 1 68  ? 29.17400  -26.25900 62.22100 1.000 60.12000  ? 68  GLU A H    1 
ATOM   1027 H  HA   . GLU A 1 68  ? 29.67000  -24.39400 60.47900 1.000 60.63000  ? 68  GLU A HA   1 
ATOM   1028 H  HB2  . GLU A 1 68  ? 31.29200  -26.50700 61.38900 1.000 62.15000  ? 68  GLU A HB2  1 
ATOM   1029 H  HB3  . GLU A 1 68  ? 31.84200  -25.42800 60.35900 1.000 62.15000  ? 68  GLU A HB3  1 
ATOM   1030 H  HG2  . GLU A 1 68  ? 31.68100  -23.77100 61.92000 1.000 63.63000  ? 68  GLU A HG2  1 
ATOM   1031 H  HG3  . GLU A 1 68  ? 30.93100  -24.74000 62.93200 1.000 63.63000  ? 68  GLU A HG3  1 
ATOM   1032 N  N    . ALA A 1 69  ? 29.29600  -27.29200 59.17800 1.000 49.93230  ? 69  ALA A N    1 
ATOM   1033 C  CA   . ALA A 1 69  ? 29.11100  -27.97900 57.90400 1.000 49.80597  ? 69  ALA A CA   1 
ATOM   1034 C  C    . ALA A 1 69  ? 27.90800  -27.42600 57.15000 1.000 52.36154  ? 69  ALA A C    1 
ATOM   1035 O  O    . ALA A 1 69  ? 27.99300  -27.13400 55.95200 1.000 50.16917  ? 69  ALA A O    1 
ATOM   1036 C  CB   . ALA A 1 69  ? 28.95600  -29.48200 58.13600 1.000 48.60583  ? 69  ALA A CB   1 
ATOM   1037 H  H    . ALA A 1 69  ? 29.19100  -27.78900 59.87200 1.000 60.03000  ? 69  ALA A H    1 
ATOM   1038 H  HA   . ALA A 1 69  ? 29.90000  -27.83700 57.35800 1.000 59.88000  ? 69  ALA A HA   1 
ATOM   1039 H  HB1  . ALA A 1 69  ? 28.83600  -29.92300 57.28000 1.000 58.44000  ? 69  ALA A HB1  1 
ATOM   1040 H  HB2  . ALA A 1 69  ? 29.75500  -29.81900 58.57200 1.000 58.44000  ? 69  ALA A HB2  1 
ATOM   1041 H  HB3  . ALA A 1 69  ? 28.18200  -29.63700 58.69900 1.000 58.44000  ? 69  ALA A HB3  1 
ATOM   1042 N  N    . PHE A 1 70  ? 26.77100  -27.27300 57.83500 1.000 48.49792  ? 70  PHE A N    1 
ATOM   1043 C  CA   . PHE A 1 70  ? 25.57800  -26.79000 57.14900 1.000 52.57999  ? 70  PHE A CA   1 
ATOM   1044 C  C    . PHE A 1 70  ? 25.76000  -25.35400 56.67200 1.000 52.58788  ? 70  PHE A C    1 
ATOM   1045 O  O    . PHE A 1 70  ? 25.42300  -25.02100 55.53000 1.000 52.90108  ? 70  PHE A O    1 
ATOM   1046 C  CB   . PHE A 1 70  ? 24.35000  -26.88300 58.05100 1.000 49.14273  ? 70  PHE A CB   1 
ATOM   1047 C  CG   . PHE A 1 70  ? 23.10100  -26.36600 57.39800 1.000 49.20590  ? 70  PHE A CG   1 
ATOM   1048 C  CD1  . PHE A 1 70  ? 22.41300  -27.14300 56.48100 1.000 53.83277  ? 70  PHE A CD1  1 
ATOM   1049 C  CD2  . PHE A 1 70  ? 22.63300  -25.09200 57.67300 1.000 49.71122  ? 70  PHE A CD2  1 
ATOM   1050 C  CE1  . PHE A 1 70  ? 21.27000  -26.66800 55.86500 1.000 53.00636  ? 70  PHE A CE1  1 
ATOM   1051 C  CE2  . PHE A 1 70  ? 21.49200  -24.61100 57.05700 1.000 53.03004  ? 70  PHE A CE2  1 
ATOM   1052 C  CZ   . PHE A 1 70  ? 20.80900  -25.40000 56.15400 1.000 50.47710  ? 70  PHE A CZ   1 
ATOM   1053 H  H    . PHE A 1 70  ? 26.67000  -27.43800 58.67300 1.000 58.31000  ? 70  PHE A H    1 
ATOM   1054 H  HA   . PHE A 1 70  ? 25.42900  -27.36100 56.37900 1.000 63.21000  ? 70  PHE A HA   1 
ATOM   1055 H  HB2  . PHE A 1 70  ? 24.20200  -27.81300 58.28500 1.000 59.08000  ? 70  PHE A HB2  1 
ATOM   1056 H  HB3  . PHE A 1 70  ? 24.50800  -26.36000 58.85200 1.000 59.08000  ? 70  PHE A HB3  1 
ATOM   1057 H  HD1  . PHE A 1 70  ? 22.72400  -27.99600 56.27800 1.000 64.71000  ? 70  PHE A HD1  1 
ATOM   1058 H  HD2  . PHE A 1 70  ? 23.09100  -24.55500 58.27800 1.000 59.77000  ? 70  PHE A HD2  1 
ATOM   1059 H  HE1  . PHE A 1 70  ? 20.81300  -27.20200 55.25700 1.000 63.72000  ? 70  PHE A HE1  1 
ATOM   1060 H  HE2  . PHE A 1 70  ? 21.18500  -23.75500 57.25200 1.000 63.75000  ? 70  PHE A HE2  1 
ATOM   1061 H  HZ   . PHE A 1 70  ? 20.04100  -25.07800 55.74100 1.000 60.69000  ? 70  PHE A HZ   1 
ATOM   1062 N  N    . GLU A 1 71  ? 26.27700  -24.48200 57.54100 1.000 49.32433  ? 71  GLU A N    1 
ATOM   1063 C  CA   . GLU A 1 71  ? 26.44000  -23.08400 57.15600 1.000 54.04859  ? 71  GLU A CA   1 
ATOM   1064 C  C    . GLU A 1 71  ? 27.30800  -22.94400 55.91300 1.000 50.99296  ? 71  GLU A C    1 
ATOM   1065 O  O    . GLU A 1 71  ? 27.14700  -21.98500 55.14900 1.000 48.79532  ? 71  GLU A O    1 
ATOM   1066 C  CB   . GLU A 1 71  ? 27.04200  -22.28300 58.31200 1.000 52.96425  ? 71  GLU A CB   1 
ATOM   1067 C  CG   . GLU A 1 71  ? 26.10000  -22.06900 59.49200 1.000 62.55487  ? 71  GLU A CG   1 
ATOM   1068 C  CD   . GLU A 1 71  ? 24.84800  -21.29700 59.11400 1.000 75.78014  ? 71  GLU A CD   1 
ATOM   1069 O  OE1  . GLU A 1 71  ? 24.97400  -20.24700 58.44800 1.000 80.22278  ? 71  GLU A OE1  1 
ATOM   1070 O  OE2  . GLU A 1 71  ? 23.73900  -21.73900 59.48700 1.000 72.71398  ? 71  GLU A OE2  1 
ATOM   1071 H  H    . GLU A 1 71  ? 26.53500  -24.67100 58.33900 1.000 59.30000  ? 71  GLU A H    1 
ATOM   1072 H  HA   . GLU A 1 71  ? 25.56600  -22.71400 56.95900 1.000 64.97000  ? 71  GLU A HA   1 
ATOM   1073 H  HB2  . GLU A 1 71  ? 27.82200  -22.75500 58.64300 1.000 63.67000  ? 71  GLU A HB2  1 
ATOM   1074 H  HB3  . GLU A 1 71  ? 27.29900  -21.40800 57.98100 1.000 63.67000  ? 71  GLU A HB3  1 
ATOM   1075 H  HG2  . GLU A 1 71  ? 25.82500  -22.93300 59.83800 1.000 75.18000  ? 71  GLU A HG2  1 
ATOM   1076 H  HG3  . GLU A 1 71  ? 26.56400  -21.56900 60.18100 1.000 75.18000  ? 71  GLU A HG3  1 
ATOM   1077 N  N    . TYR A 1 72  ? 28.22300  -23.88700 55.68600 1.000 46.86351  ? 72  TYR A N    1 
ATOM   1078 C  CA   . TYR A 1 72  ? 29.14000  -23.80300 54.55600 1.000 52.52998  ? 72  TYR A CA   1 
ATOM   1079 C  C    . TYR A 1 72  ? 28.57600  -24.46800 53.30200 1.000 46.52663  ? 72  TYR A C    1 
ATOM   1080 O  O    . TYR A 1 72  ? 28.64200  -23.89000 52.21400 1.000 48.95061  ? 72  TYR A O    1 
ATOM   1081 C  CB   . TYR A 1 72  ? 30.48800  -24.43700 54.92200 1.000 50.71398  ? 72  TYR A CB   1 
ATOM   1082 C  CG   . TYR A 1 72  ? 31.61100  -24.06100 53.97800 1.000 51.56671  ? 72  TYR A CG   1 
ATOM   1083 C  CD1  . TYR A 1 72  ? 32.02900  -22.74200 53.85500 1.000 52.32469  ? 72  TYR A CD1  1 
ATOM   1084 C  CD2  . TYR A 1 72  ? 32.24900  -25.02300 53.20600 1.000 54.29598  ? 72  TYR A CD2  1 
ATOM   1085 C  CE1  . TYR A 1 72  ? 33.05100  -22.39100 52.99200 1.000 49.71122  ? 72  TYR A CE1  1 
ATOM   1086 C  CE2  . TYR A 1 72  ? 33.27300  -24.68100 52.33900 1.000 50.71398  ? 72  TYR A CE2  1 
ATOM   1087 C  CZ   . TYR A 1 72  ? 33.67000  -23.36500 52.23800 1.000 51.23772  ? 72  TYR A CZ   1 
ATOM   1088 O  OH   . TYR A 1 72  ? 34.68800  -23.02300 51.37700 1.000 54.01963  ? 72  TYR A OH   1 
ATOM   1089 H  H    . TYR A 1 72  ? 28.33000  -24.58600 56.17400 1.000 56.35000  ? 72  TYR A H    1 
ATOM   1090 H  HA   . TYR A 1 72  ? 29.28900  -22.86600 54.35500 1.000 63.15000  ? 72  TYR A HA   1 
ATOM   1091 H  HB2  . TYR A 1 72  ? 30.73800  -24.14600 55.81300 1.000 60.97000  ? 72  TYR A HB2  1 
ATOM   1092 H  HB3  . TYR A 1 72  ? 30.39400  -25.40300 54.90300 1.000 60.97000  ? 72  TYR A HB3  1 
ATOM   1093 H  HD1  . TYR A 1 72  ? 31.61400  -22.08200 54.36300 1.000 62.90000  ? 72  TYR A HD1  1 
ATOM   1094 H  HD2  . TYR A 1 72  ? 31.98300  -25.91100 53.27200 1.000 65.27000  ? 72  TYR A HD2  1 
ATOM   1095 H  HE1  . TYR A 1 72  ? 33.31900  -21.50300 52.92100 1.000 59.77000  ? 72  TYR A HE1  1 
ATOM   1096 H  HE2  . TYR A 1 72  ? 33.69100  -25.33600 51.82800 1.000 60.97000  ? 72  TYR A HE2  1 
ATOM   1097 H  HH   . TYR A 1 72  ? 34.83400  -22.19700 51.41800 1.000 64.94000  ? 72  TYR A HH   1 
ATOM   1098 N  N    . TYR A 1 73  ? 28.01900  -25.67400 53.43900 1.000 50.53237  ? 73  TYR A N    1 
ATOM   1099 C  CA   . TYR A 1 73  ? 27.55900  -26.44900 52.29300 1.000 46.66349  ? 73  TYR A CA   1 
ATOM   1100 C  C    . TYR A 1 73  ? 26.05800  -26.36700 52.05800 1.000 51.30878  ? 73  TYR A C    1 
ATOM   1101 O  O    . TYR A 1 73  ? 25.60700  -26.67300 50.94900 1.000 47.11618  ? 73  TYR A O    1 
ATOM   1102 C  CB   . TYR A 1 73  ? 27.94200  -27.92400 52.46600 1.000 45.41071  ? 73  TYR A CB   1 
ATOM   1103 C  CG   . TYR A 1 73  ? 29.42900  -28.16000 52.57100 1.000 49.45067  ? 73  TYR A CG   1 
ATOM   1104 C  CD1  . TYR A 1 73  ? 30.25100  -28.01100 51.46300 1.000 46.24502  ? 73  TYR A CD1  1 
ATOM   1105 C  CD2  . TYR A 1 73  ? 30.01200  -28.53100 53.77500 1.000 43.89474  ? 73  TYR A CD2  1 
ATOM   1106 C  CE1  . TYR A 1 73  ? 31.61000  -28.22300 51.55000 1.000 44.86591  ? 73  TYR A CE1  1 
ATOM   1107 C  CE2  . TYR A 1 73  ? 31.37500  -28.74600 53.87100 1.000 46.74508  ? 73  TYR A CE2  1 
ATOM   1108 C  CZ   . TYR A 1 73  ? 32.16800  -28.59000 52.75300 1.000 47.06617  ? 73  TYR A CZ   1 
ATOM   1109 O  OH   . TYR A 1 73  ? 33.52600  -28.80100 52.83400 1.000 52.24574  ? 73  TYR A OH   1 
ATOM   1110 H  H    . TYR A 1 73  ? 27.89700  -26.06600 54.19400 1.000 60.75000  ? 73  TYR A H    1 
ATOM   1111 H  HA   . TYR A 1 73  ? 28.00100  -26.10700 51.50100 1.000 56.11000  ? 73  TYR A HA   1 
ATOM   1112 H  HB2  . TYR A 1 73  ? 27.53100  -28.25900 53.27900 1.000 54.60000  ? 73  TYR A HB2  1 
ATOM   1113 H  HB3  . TYR A 1 73  ? 27.61600  -28.42200 51.70000 1.000 54.60000  ? 73  TYR A HB3  1 
ATOM   1114 H  HD1  . TYR A 1 73  ? 29.87800  -27.76300 50.64800 1.000 55.61000  ? 73  TYR A HD1  1 
ATOM   1115 H  HD2  . TYR A 1 73  ? 29.47800  -28.63700 54.52900 1.000 52.79000  ? 73  TYR A HD2  1 
ATOM   1116 H  HE1  . TYR A 1 73  ? 32.14800  -28.11800 50.79800 1.000 53.95000  ? 73  TYR A HE1  1 
ATOM   1117 H  HE2  . TYR A 1 73  ? 31.75400  -28.99400 54.68300 1.000 56.21000  ? 73  TYR A HE2  1 
ATOM   1118 H  HH   . TYR A 1 73  ? 33.73700  -29.01800 53.61700 1.000 62.81000  ? 73  TYR A HH   1 
ATOM   1119 N  N    . HIS A 1 74  ? 25.27900  -25.97100 53.06500 1.000 46.36082  ? 74  HIS A N    1 
ATOM   1120 C  CA   . HIS A 1 74  ? 23.82000  -25.91800 52.95900 1.000 51.80621  ? 74  HIS A CA   1 
ATOM   1121 C  C    . HIS A 1 74  ? 23.23400  -27.30400 52.69300 1.000 50.72713  ? 74  HIS A C    1 
ATOM   1122 O  O    . HIS A 1 74  ? 22.27500  -27.45900 51.93500 1.000 48.73479  ? 74  HIS A O    1 
ATOM   1123 C  CB   . HIS A 1 74  ? 23.37600  -24.92800 51.87700 1.000 52.07203  ? 74  HIS A CB   1 
ATOM   1124 C  CG   . HIS A 1 74  ? 23.53300  -23.49200 52.26800 1.000 52.27995  ? 74  HIS A CG   1 
ATOM   1125 N  ND1  . HIS A 1 74  ? 23.04200  -22.45500 51.50500 1.000 57.98853  ? 74  HIS A ND1  1 
ATOM   1126 C  CD2  . HIS A 1 74  ? 24.12800  -22.91900 53.34200 1.000 53.90646  ? 74  HIS A CD2  1 
ATOM   1127 C  CE1  . HIS A 1 74  ? 23.32600  -21.30500 52.09200 1.000 57.75692  ? 74  HIS A CE1  1 
ATOM   1128 N  NE2  . HIS A 1 74  ? 23.98400  -21.55900 53.20800 1.000 53.43799  ? 74  HIS A NE2  1 
ATOM   1129 H  H    . HIS A 1 74  ? 25.57600  -25.72500 53.83400 1.000 55.75000  ? 74  HIS A H    1 
ATOM   1130 H  HA   . HIS A 1 74  ? 23.46700  -25.60800 53.80800 1.000 62.28000  ? 74  HIS A HA   1 
ATOM   1131 H  HB2  . HIS A 1 74  ? 23.91000  -25.07800 51.08100 1.000 62.60000  ? 74  HIS A HB2  1 
ATOM   1132 H  HB3  . HIS A 1 74  ? 22.43800  -25.08000 51.68200 1.000 62.60000  ? 74  HIS A HB3  1 
ATOM   1133 H  HD1  . HIS A 1 74  ? 22.61600  -22.54200 50.76300 1.000 69.70000  ? 74  HIS A HD1  1 
ATOM   1134 H  HD2  . HIS A 1 74  ? 24.55400  -23.36300 54.03900 1.000 64.80000  ? 74  HIS A HD2  1 
ATOM   1135 H  HE1  . HIS A 1 74  ? 23.10100  -20.46100 51.77300 1.000 69.42000  ? 74  HIS A HE1  1 
ATOM   1136 N  N    . THR A 1 75  ? 23.81100  -28.32300 53.32800 1.000 49.42961  ? 75  THR A N    1 
ATOM   1137 C  CA   . THR A 1 75  ? 23.30700  -29.68200 53.20200 1.000 50.09811  ? 75  THR A CA   1 
ATOM   1138 C  C    . THR A 1 75  ? 23.62300  -30.45500 54.47400 1.000 50.75082  ? 75  THR A C    1 
ATOM   1139 O  O    . THR A 1 75  ? 24.66600  -30.24800 55.10000 1.000 50.10338  ? 75  THR A O    1 
ATOM   1140 C  CB   . THR A 1 75  ? 23.91300  -30.40900 51.99400 1.000 49.95336  ? 75  THR A CB   1 
ATOM   1141 O  OG1  . THR A 1 75  ? 23.32300  -31.71000 51.87300 1.000 51.17982  ? 75  THR A OG1  1 
ATOM   1142 C  CG2  . THR A 1 75  ? 25.41800  -30.56100 52.15500 1.000 51.32721  ? 75  THR A CG2  1 
ATOM   1143 H  H    . THR A 1 75  ? 24.49900  -28.24900 53.83900 1.000 59.43000  ? 75  THR A H    1 
ATOM   1144 H  HA   . THR A 1 75  ? 22.34400  -29.64900 53.09100 1.000 60.23000  ? 75  THR A HA   1 
ATOM   1145 H  HB   . THR A 1 75  ? 23.74000  -29.89400 51.19100 1.000 60.06000  ? 75  THR A HB   1 
ATOM   1146 H  HG1  . THR A 1 75  ? 23.66300  -32.12000 51.22300 1.000 61.53000  ? 75  THR A HG1  1 
ATOM   1147 H  HG21 . THR A 1 75  ? 25.81600  -30.83800 51.31500 1.000 61.71000  ? 75  THR A HG21 1 
ATOM   1148 H  HG22 . THR A 1 75  ? 25.81000  -29.71600 52.42600 1.000 61.71000  ? 75  THR A HG22 1 
ATOM   1149 H  HG23 . THR A 1 75  ? 25.61400  -31.23000 52.83000 1.000 61.71000  ? 75  THR A HG23 1 
ATOM   1150 N  N    . THR A 1 76  ? 22.70600  -31.35100 54.84700 1.000 49.53752  ? 76  THR A N    1 
ATOM   1151 C  CA   . THR A 1 76  ? 22.91600  -32.27300 55.95700 1.000 52.68790  ? 76  THR A CA   1 
ATOM   1152 C  C    . THR A 1 76  ? 22.89900  -33.72600 55.49200 1.000 54.16439  ? 76  THR A C    1 
ATOM   1153 O  O    . THR A 1 76  ? 22.60900  -34.62700 56.28600 1.000 55.80406  ? 76  THR A O    1 
ATOM   1154 C  CB   . THR A 1 76  ? 21.86700  -32.06100 57.05100 1.000 50.79293  ? 76  THR A CB   1 
ATOM   1155 O  OG1  . THR A 1 76  ? 20.55800  -32.29200 56.51700 1.000 48.46634  ? 76  THR A OG1  1 
ATOM   1156 C  CG2  . THR A 1 76  ? 21.94800  -30.64400 57.60800 1.000 51.41932  ? 76  THR A CG2  1 
ATOM   1157 H  H    . THR A 1 76  ? 21.94200  -31.44300 54.46400 1.000 59.56000  ? 76  THR A H    1 
ATOM   1158 H  HA   . THR A 1 76  ? 23.78600  -32.09000 56.34500 1.000 63.34000  ? 76  THR A HA   1 
ATOM   1159 H  HB   . THR A 1 76  ? 22.03000  -32.68200 57.77800 1.000 61.07000  ? 76  THR A HB   1 
ATOM   1160 H  HG1  . THR A 1 76  ? 19.98100  -32.20700 57.12300 1.000 58.27000  ? 76  THR A HG1  1 
ATOM   1161 H  HG21 . THR A 1 76  ? 21.31500  -30.53700 58.33500 1.000 61.82000  ? 76  THR A HG21 1 
ATOM   1162 H  HG22 . THR A 1 76  ? 22.84200  -30.46900 57.94100 1.000 61.82000  ? 76  THR A HG22 1 
ATOM   1163 H  HG23 . THR A 1 76  ? 21.74000  -30.00200 56.91200 1.000 61.82000  ? 76  THR A HG23 1 
ATOM   1164 N  N    . ASP A 1 77  ? 23.19000  -33.96900 54.22000 1.000 50.20339  ? 77  ASP A N    1 
ATOM   1165 C  CA   . ASP A 1 77  ? 23.31400  -35.32900 53.71600 1.000 51.87990  ? 77  ASP A CA   1 
ATOM   1166 C  C    . ASP A 1 77  ? 24.48300  -36.01600 54.41600 1.000 53.99858  ? 77  ASP A C    1 
ATOM   1167 O  O    . ASP A 1 77  ? 25.62800  -35.56000 54.27700 1.000 52.51945  ? 77  ASP A O    1 
ATOM   1168 C  CB   . ASP A 1 77  ? 23.52900  -35.31800 52.20400 1.000 54.75920  ? 77  ASP A CB   1 
ATOM   1169 C  CG   . ASP A 1 77  ? 23.48800  -36.71000 51.59400 1.000 59.64399  ? 77  ASP A CG   1 
ATOM   1170 O  OD1  . ASP A 1 77  ? 23.96900  -37.66900 52.23500 1.000 62.49434  ? 77  ASP A OD1  1 
ATOM   1171 O  OD2  . ASP A 1 77  ? 22.97900  -36.84400 50.46100 1.000 65.01569  ? 77  ASP A OD2  1 
ATOM   1172 H  H    . ASP A 1 77  ? 23.32200  -33.36100 53.62700 1.000 60.36000  ? 77  ASP A H    1 
ATOM   1173 H  HA   . ASP A 1 77  ? 22.50000  -35.82500 53.89500 1.000 62.37000  ? 77  ASP A HA   1 
ATOM   1174 H  HB2  . ASP A 1 77  ? 22.83000  -34.78800 51.79000 1.000 65.82000  ? 77  ASP A HB2  1 
ATOM   1175 H  HB3  . ASP A 1 77  ? 24.39700  -34.93100 52.01100 1.000 65.82000  ? 77  ASP A HB3  1 
ATOM   1176 N  N    . PRO A 1 78  ? 24.25300  -37.10100 55.16200 1.000 58.64124  ? 78  PRO A N    1 
ATOM   1177 C  CA   . PRO A 1 78  ? 25.36300  -37.70500 55.92100 1.000 60.14932  ? 78  PRO A CA   1 
ATOM   1178 C  C    . PRO A 1 78  ? 26.55200  -38.09800 55.06200 1.000 59.86770  ? 78  PRO A C    1 
ATOM   1179 O  O    . PRO A 1 78  ? 27.69000  -38.05700 55.54600 1.000 60.59411  ? 78  PRO A O    1 
ATOM   1180 C  CB   . PRO A 1 78  ? 24.72900  -38.94000 56.58100 1.000 59.09919  ? 78  PRO A CB   1 
ATOM   1181 C  CG   . PRO A 1 78  ? 23.26700  -38.81600 56.41000 1.000 58.71493  ? 78  PRO A CG   1 
ATOM   1182 C  CD   . PRO A 1 78  ? 22.97100  -37.80100 55.36000 1.000 56.28570  ? 78  PRO A CD   1 
ATOM   1183 H  HA   . PRO A 1 78  ? 25.65000  -37.08300 56.60700 1.000 72.29000  ? 78  PRO A HA   1 
ATOM   1184 H  HB2  . PRO A 1 78  ? 25.05600  -39.74200 56.14500 1.000 71.03000  ? 78  PRO A HB2  1 
ATOM   1185 H  HB3  . PRO A 1 78  ? 24.96100  -38.95600 57.52300 1.000 71.03000  ? 78  PRO A HB3  1 
ATOM   1186 H  HG2  . PRO A 1 78  ? 22.91000  -39.67800 56.14500 1.000 70.57000  ? 78  PRO A HG2  1 
ATOM   1187 H  HG3  . PRO A 1 78  ? 22.87600  -38.54100 57.25400 1.000 70.57000  ? 78  PRO A HG3  1 
ATOM   1188 H  HD2  . PRO A 1 78  ? 22.68600  -38.23200 54.53900 1.000 67.66000  ? 78  PRO A HD2  1 
ATOM   1189 H  HD3  . PRO A 1 78  ? 22.28800  -37.18400 55.66500 1.000 67.66000  ? 78  PRO A HD3  1 
ATOM   1190 N  N    . SER A 1 79  ? 26.33100  -38.47900 53.80600 1.000 56.34360  ? 79  SER A N    1 
ATOM   1191 C  CA   . SER A 1 79  ? 27.40400  -38.97300 52.95400 1.000 52.81949  ? 79  SER A CA   1 
ATOM   1192 C  C    . SER A 1 79  ? 28.03500  -37.88800 52.09300 1.000 54.35125  ? 79  SER A C    1 
ATOM   1193 O  O    . SER A 1 79  ? 28.91400  -38.19800 51.28100 1.000 54.48022  ? 79  SER A O    1 
ATOM   1194 C  CB   . SER A 1 79  ? 26.88100  -40.09600 52.05100 1.000 55.55929  ? 79  SER A CB   1 
ATOM   1195 O  OG   . SER A 1 79  ? 25.85600  -39.62400 51.19200 1.000 61.24155  ? 79  SER A OG   1 
ATOM   1196 H  H    . SER A 1 79  ? 25.56100  -38.45900 53.42300 1.000 67.73000  ? 79  SER A H    1 
ATOM   1197 H  HA   . SER A 1 79  ? 28.09900  -39.34000 53.52200 1.000 63.49000  ? 79  SER A HA   1 
ATOM   1198 H  HB2  . SER A 1 79  ? 27.61300  -40.43300 51.51200 1.000 66.79000  ? 79  SER A HB2  1 
ATOM   1199 H  HB3  . SER A 1 79  ? 26.52400  -40.80600 52.60700 1.000 66.79000  ? 79  SER A HB3  1 
ATOM   1200 H  HG   . SER A 1 79  ? 25.55500  -40.25700 50.73000 1.000 73.60000  ? 79  SER A HG   1 
ATOM   1201 N  N    . PHE A 1 80  ? 27.62500  -36.62900 52.25400 1.000 50.60870  ? 80  PHE A N    1 
ATOM   1202 C  CA   . PHE A 1 80  ? 28.12100  -35.56900 51.38200 1.000 57.49637  ? 80  PHE A CA   1 
ATOM   1203 C  C    . PHE A 1 80  ? 29.64200  -35.48000 51.43100 1.000 56.54099  ? 80  PHE A C    1 
ATOM   1204 O  O    . PHE A 1 80  ? 30.31700  -35.57800 50.40000 1.000 53.89067  ? 80  PHE A O    1 
ATOM   1205 C  CB   . PHE A 1 80  ? 27.49700  -34.23000 51.77200 1.000 52.69053  ? 80  PHE A CB   1 
ATOM   1206 C  CG   . PHE A 1 80  ? 27.88000  -33.10300 50.85900 1.000 53.72749  ? 80  PHE A CG   1 
ATOM   1207 C  CD1  . PHE A 1 80  ? 27.17600  -32.87500 49.68800 1.000 52.55104  ? 80  PHE A CD1  1 
ATOM   1208 C  CD2  . PHE A 1 80  ? 28.95100  -32.27900 51.16300 1.000 54.16176  ? 80  PHE A CD2  1 
ATOM   1209 C  CE1  . PHE A 1 80  ? 27.52700  -31.84200 48.84300 1.000 51.09034  ? 80  PHE A CE1  1 
ATOM   1210 C  CE2  . PHE A 1 80  ? 29.30700  -31.24400 50.32100 1.000 52.44313  ? 80  PHE A CE2  1 
ATOM   1211 C  CZ   . PHE A 1 80  ? 28.59500  -31.02600 49.15900 1.000 51.69830  ? 80  PHE A CZ   1 
ATOM   1212 H  H    . PHE A 1 80  ? 27.06600  -36.36700 52.85400 1.000 60.84000  ? 80  PHE A H    1 
ATOM   1213 H  HA   . PHE A 1 80  ? 27.85700  -35.77600 50.47200 1.000 69.11000  ? 80  PHE A HA   1 
ATOM   1214 H  HB2  . PHE A 1 80  ? 26.53100  -34.31600 51.74900 1.000 63.34000  ? 80  PHE A HB2  1 
ATOM   1215 H  HB3  . PHE A 1 80  ? 27.78800  -33.99800 52.66800 1.000 63.34000  ? 80  PHE A HB3  1 
ATOM   1216 H  HD1  . PHE A 1 80  ? 26.45800  -33.42400 49.46900 1.000 63.17000  ? 80  PHE A HD1  1 
ATOM   1217 H  HD2  . PHE A 1 80  ? 29.43500  -32.42300 51.94400 1.000 65.11000  ? 80  PHE A HD2  1 
ATOM   1218 H  HE1  . PHE A 1 80  ? 27.04600  -31.69700 48.06100 1.000 61.42000  ? 80  PHE A HE1  1 
ATOM   1219 H  HE2  . PHE A 1 80  ? 30.02700  -30.69500 50.53600 1.000 63.05000  ? 80  PHE A HE2  1 
ATOM   1220 H  HZ   . PHE A 1 80  ? 28.83400  -30.33000 48.59000 1.000 62.15000  ? 80  PHE A HZ   1 
ATOM   1221 N  N    . LEU A 1 81  ? 30.19900  -35.28200 52.62900 1.000 52.04571  ? 81  LEU A N    1 
ATOM   1222 C  CA   . LEU A 1 81  ? 31.64200  -35.09700 52.74800 1.000 57.48058  ? 81  LEU A CA   1 
ATOM   1223 C  C    . LEU A 1 81  ? 32.40100  -36.26300 52.12700 1.000 54.29072  ? 81  LEU A C    1 
ATOM   1224 O  O    . LEU A 1 81  ? 33.38400  -36.06000 51.40600 1.000 54.42495  ? 81  LEU A O    1 
ATOM   1225 C  CB   . LEU A 1 81  ? 32.03300  -34.92900 54.21500 1.000 64.11821  ? 81  LEU A CB   1 
ATOM   1226 C  CG   . LEU A 1 81  ? 32.38200  -33.51000 54.67600 1.000 73.02454  ? 81  LEU A CG   1 
ATOM   1227 C  CD1  . LEU A 1 81  ? 33.58000  -32.95500 53.91000 1.000 67.13437  ? 81  LEU A CD1  1 
ATOM   1228 C  CD2  . LEU A 1 81  ? 31.18000  -32.58700 54.53600 1.000 66.87118  ? 81  LEU A CD2  1 
ATOM   1229 H  H    . LEU A 1 81  ? 29.77000  -35.25100 53.37400 1.000 62.57000  ? 81  LEU A H    1 
ATOM   1230 H  HA   . LEU A 1 81  ? 31.89100  -34.28800 52.27500 1.000 69.09000  ? 81  LEU A HA   1 
ATOM   1231 H  HB2  . LEU A 1 81  ? 31.28900  -35.22900 54.76000 1.000 77.05000  ? 81  LEU A HB2  1 
ATOM   1232 H  HB3  . LEU A 1 81  ? 32.81200  -35.48200 54.38400 1.000 77.05000  ? 81  LEU A HB3  1 
ATOM   1233 H  HG   . LEU A 1 81  ? 32.62800  -33.54600 55.61300 1.000 87.74000  ? 81  LEU A HG   1 
ATOM   1234 H  HD11 . LEU A 1 81  ? 33.79900  -32.07700 54.26000 1.000 80.67000  ? 81  LEU A HD11 1 
ATOM   1235 H  HD12 . LEU A 1 81  ? 34.33300  -33.55500 54.02400 1.000 80.67000  ? 81  LEU A HD12 1 
ATOM   1236 H  HD13 . LEU A 1 81  ? 33.35000  -32.88800 52.97000 1.000 80.67000  ? 81  LEU A HD13 1 
ATOM   1237 H  HD21 . LEU A 1 81  ? 31.42900  -31.69700 54.83000 1.000 80.36000  ? 81  LEU A HD21 1 
ATOM   1238 H  HD22 . LEU A 1 81  ? 30.90600  -32.56300 53.60600 1.000 80.36000  ? 81  LEU A HD22 1 
ATOM   1239 H  HD23 . LEU A 1 81  ? 30.45600  -32.92600 55.08500 1.000 80.36000  ? 81  LEU A HD23 1 
ATOM   1240 N  N    . GLY A 1 82  ? 31.96000  -37.49200 52.39700 1.000 56.41992  ? 82  GLY A N    1 
ATOM   1241 C  CA   . GLY A 1 82  ? 32.60400  -38.64200 51.78500 1.000 49.52173  ? 82  GLY A CA   1 
ATOM   1242 C  C    . GLY A 1 82  ? 32.61500  -38.55700 50.27100 1.000 55.85933  ? 82  GLY A C    1 
ATOM   1243 O  O    . GLY A 1 82  ? 33.63700  -38.80800 49.62800 1.000 54.59602  ? 82  GLY A O    1 
ATOM   1244 H  H    . GLY A 1 82  ? 31.30400  -37.68000 52.92100 1.000 67.82000  ? 82  GLY A H    1 
ATOM   1245 H  HA2  . GLY A 1 82  ? 33.52100  -38.70000 52.09500 1.000 59.54000  ? 82  GLY A HA2  1 
ATOM   1246 H  HA3  . GLY A 1 82  ? 32.13200  -39.45000 52.04200 1.000 59.54000  ? 82  GLY A HA3  1 
ATOM   1247 N  N    . ARG A 1 83  ? 31.47500  -38.19200 49.68000 1.000 53.88278  ? 83  ARG A N    1 
ATOM   1248 C  CA   . ARG A 1 83  ? 31.39500  -38.11100 48.22500 1.000 56.09883  ? 83  ARG A CA   1 
ATOM   1249 C  C    . ARG A 1 83  ? 32.19000  -36.92400 47.69800 1.000 51.95623  ? 83  ARG A C    1 
ATOM   1250 O  O    . ARG A 1 83  ? 32.81300  -37.01000 46.63300 1.000 52.33259  ? 83  ARG A O    1 
ATOM   1251 C  CB   . ARG A 1 83  ? 29.93200  -38.02900 47.78800 1.000 50.99559  ? 83  ARG A CB   1 
ATOM   1252 C  CG   . ARG A 1 83  ? 29.13500  -39.28300 48.13400 1.000 59.69400  ? 83  ARG A CG   1 
ATOM   1253 C  CD   . ARG A 1 83  ? 27.72400  -39.25700 47.56500 1.000 59.89666  ? 83  ARG A CD   1 
ATOM   1254 N  NE   . ARG A 1 83  ? 26.84400  -38.35800 48.30300 1.000 59.25447  ? 83  ARG A NE   1 
ATOM   1255 C  CZ   . ARG A 1 83  ? 26.56600  -37.11200 47.94300 1.000 56.60152  ? 83  ARG A CZ   1 
ATOM   1256 N  NH1  . ARG A 1 83  ? 27.09500  -36.57100 46.85700 1.000 53.44851  ? 83  ARG A NH1  1 
ATOM   1257 N  NH2  . ARG A 1 83  ? 25.73600  -36.39100 48.69000 1.000 53.28534  ? 83  ARG A NH2  1 
ATOM   1258 H  H    . ARG A 1 83  ? 30.74800  -37.99100 50.09200 1.000 64.77000  ? 83  ARG A H    1 
ATOM   1259 H  HA   . ARG A 1 83  ? 31.77500  -38.91700 47.84000 1.000 67.43000  ? 83  ARG A HA   1 
ATOM   1260 H  HB2  . ARG A 1 83  ? 29.51300  -37.27500 48.23200 1.000 61.31000  ? 83  ARG A HB2  1 
ATOM   1261 H  HB3  . ARG A 1 83  ? 29.89700  -37.90800 46.82600 1.000 61.31000  ? 83  ARG A HB3  1 
ATOM   1262 H  HG2  . ARG A 1 83  ? 29.59100  -40.05800 47.77100 1.000 71.74000  ? 83  ARG A HG2  1 
ATOM   1263 H  HG3  . ARG A 1 83  ? 29.06800  -39.35900 49.09900 1.000 71.74000  ? 83  ARG A HG3  1 
ATOM   1264 H  HD2  . ARG A 1 83  ? 27.75900  -38.95500 46.64400 1.000 71.99000  ? 83  ARG A HD2  1 
ATOM   1265 H  HD3  . ARG A 1 83  ? 27.34800  -40.15000 47.60800 1.000 71.99000  ? 83  ARG A HD3  1 
ATOM   1266 H  HE   . ARG A 1 83  ? 26.48000  -38.65700 49.02300 1.000 71.22000  ? 83  ARG A HE   1 
ATOM   1267 H  HH11 . ARG A 1 83  ? 27.63300  -37.02800 46.36600 1.000 64.25000  ? 83  ARG A HH11 1 
ATOM   1268 H  HH12 . ARG A 1 83  ? 26.90100  -35.76100 46.64200 1.000 64.25000  ? 83  ARG A HH12 1 
ATOM   1269 H  HH21 . ARG A 1 83  ? 25.38700  -36.73400 49.39800 1.000 64.06000  ? 83  ARG A HH21 1 
ATOM   1270 H  HH22 . ARG A 1 83  ? 25.54800  -35.58200 48.46700 1.000 64.06000  ? 83  ARG A HH22 1 
ATOM   1271 N  N    . TYR A 1 84  ? 32.18800  -35.81000 48.43200 1.000 47.82942  ? 84  TYR A N    1 
ATOM   1272 C  CA   . TYR A 1 84  ? 32.99700  -34.66300 48.03500 1.000 47.61097  ? 84  TYR A CA   1 
ATOM   1273 C  C    . TYR A 1 84  ? 34.48200  -35.00300 48.07000 1.000 57.35161  ? 84  TYR A C    1 
ATOM   1274 O  O    . TYR A 1 84  ? 35.22400  -34.67500 47.13600 1.000 55.02239  ? 84  TYR A O    1 
ATOM   1275 C  CB   . TYR A 1 84  ? 32.68400  -33.47500 48.94700 1.000 48.60320  ? 84  TYR A CB   1 
ATOM   1276 C  CG   . TYR A 1 84  ? 33.58700  -32.27400 48.76800 1.000 51.59303  ? 84  TYR A CG   1 
ATOM   1277 C  CD1  . TYR A 1 84  ? 33.89900  -31.79200 47.50400 1.000 52.83002  ? 84  TYR A CD1  1 
ATOM   1278 C  CD2  . TYR A 1 84  ? 34.10900  -31.60700 49.86900 1.000 54.05911  ? 84  TYR A CD2  1 
ATOM   1279 C  CE1  . TYR A 1 84  ? 34.71900  -30.69000 47.34100 1.000 51.00612  ? 84  TYR A CE1  1 
ATOM   1280 C  CE2  . TYR A 1 84  ? 34.92900  -30.50400 49.71600 1.000 52.90371  ? 84  TYR A CE2  1 
ATOM   1281 C  CZ   . TYR A 1 84  ? 35.23000  -30.05000 48.45100 1.000 57.27792  ? 84  TYR A CZ   1 
ATOM   1282 O  OH   . TYR A 1 84  ? 36.04700  -28.95200 48.29400 1.000 56.56994  ? 84  TYR A OH   1 
ATOM   1283 H  H    . TYR A 1 84  ? 31.73200  -35.69600 49.15200 1.000 57.51000  ? 84  TYR A H    1 
ATOM   1284 H  HA   . TYR A 1 84  ? 32.77400  -34.40900 47.12600 1.000 57.25000  ? 84  TYR A HA   1 
ATOM   1285 H  HB2  . TYR A 1 84  ? 31.77500  -33.18400 48.77100 1.000 58.44000  ? 84  TYR A HB2  1 
ATOM   1286 H  HB3  . TYR A 1 84  ? 32.76600  -33.76500 49.86900 1.000 58.44000  ? 84  TYR A HB3  1 
ATOM   1287 H  HD1  . TYR A 1 84  ? 33.55000  -32.21800 46.75400 1.000 63.51000  ? 84  TYR A HD1  1 
ATOM   1288 H  HD2  . TYR A 1 84  ? 33.90300  -31.90700 50.72500 1.000 64.99000  ? 84  TYR A HD2  1 
ATOM   1289 H  HE1  . TYR A 1 84  ? 34.92400  -30.38300 46.48800 1.000 61.32000  ? 84  TYR A HE1  1 
ATOM   1290 H  HE2  . TYR A 1 84  ? 35.27600  -30.07200 50.46300 1.000 63.60000  ? 84  TYR A HE2  1 
ATOM   1291 H  HH   . TYR A 1 84  ? 36.32200  -28.68900 49.04200 1.000 68.00000  ? 84  TYR A HH   1 
ATOM   1292 N  N    . MET A 1 85  ? 34.93000  -35.68400 49.12900 1.000 53.27481  ? 85  MET A N    1 
ATOM   1293 C  CA   . MET A 1 85  ? 36.34400  -36.02500 49.24900 1.000 52.06151  ? 85  MET A CA   1 
ATOM   1294 C  C    . MET A 1 85  ? 36.76100  -37.06000 48.20900 1.000 53.58011  ? 85  MET A C    1 
ATOM   1295 O  O    . MET A 1 85  ? 37.85700  -36.97000 47.64300 1.000 55.46718  ? 85  MET A O    1 
ATOM   1296 C  CB   . MET A 1 85  ? 36.63800  -36.53900 50.66000 1.000 56.05409  ? 85  MET A CB   1 
ATOM   1297 C  CG   . MET A 1 85  ? 36.70300  -35.44800 51.72400 1.000 49.79018  ? 85  MET A CG   1 
ATOM   1298 S  SD   . MET A 1 85  ? 37.99500  -34.22600 51.42600 1.000 59.82823  ? 85  MET A SD   1 
ATOM   1299 C  CE   . MET A 1 85  ? 37.00700  -32.76000 51.14900 1.000 55.45928  ? 85  MET A CE   1 
ATOM   1300 H  H    . MET A 1 85  ? 34.44100  -35.95500 49.78200 1.000 64.04000  ? 85  MET A H    1 
ATOM   1301 H  HA   . MET A 1 85  ? 36.86600  -35.21900 49.10700 1.000 62.59000  ? 85  MET A HA   1 
ATOM   1302 H  HB2  . MET A 1 85  ? 35.93700  -37.15800 50.91600 1.000 67.38000  ? 85  MET A HB2  1 
ATOM   1303 H  HB3  . MET A 1 85  ? 37.49500  -36.99300 50.65200 1.000 67.38000  ? 85  MET A HB3  1 
ATOM   1304 H  HG2  . MET A 1 85  ? 35.85300  -34.98200 51.74600 1.000 59.86000  ? 85  MET A HG2  1 
ATOM   1305 H  HG3  . MET A 1 85  ? 36.87800  -35.86000 52.58400 1.000 59.86000  ? 85  MET A HG3  1 
ATOM   1306 H  HE1  . MET A 1 85  ? 37.59400  -31.99100 51.08200 1.000 66.67000  ? 85  MET A HE1  1 
ATOM   1307 H  HE2  . MET A 1 85  ? 36.50700  -32.86800 50.32400 1.000 66.67000  ? 85  MET A HE2  1 
ATOM   1308 H  HE3  . MET A 1 85  ? 36.39600  -32.64600 51.89300 1.000 66.67000  ? 85  MET A HE3  1 
ATOM   1309 N  N    . SER A 1 86  ? 35.91000  -38.05700 47.95000 1.000 53.20112  ? 86  SER A N    1 
ATOM   1310 C  CA   . SER A 1 86  ? 36.25200  -39.06700 46.95300 1.000 55.76721  ? 86  SER A CA   1 
ATOM   1311 C  C    . SER A 1 86  ? 36.40800  -38.44100 45.57300 1.000 52.79580  ? 86  SER A C    1 
ATOM   1312 O  O    . SER A 1 86  ? 37.34100  -38.77400 44.83300 1.000 54.61181  ? 86  SER A O    1 
ATOM   1313 C  CB   . SER A 1 86  ? 35.18700  -40.16400 46.91900 1.000 55.39612  ? 86  SER A CB   1 
ATOM   1314 O  OG   . SER A 1 86  ? 34.84400  -40.58900 48.22500 1.000 69.16619  ? 86  SER A OG   1 
ATOM   1315 H  H    . SER A 1 86  ? 35.14600  -38.16700 48.33100 1.000 63.96000  ? 86  SER A H    1 
ATOM   1316 H  HA   . SER A 1 86  ? 37.09500  -39.47700 47.20300 1.000 67.03000  ? 86  SER A HA   1 
ATOM   1317 H  HB2  . SER A 1 86  ? 34.39300  -39.81700 46.48300 1.000 66.59000  ? 86  SER A HB2  1 
ATOM   1318 H  HB3  . SER A 1 86  ? 35.53300  -40.92200 46.42300 1.000 66.59000  ? 86  SER A HB3  1 
ATOM   1319 H  HG   . SER A 1 86  ? 34.23900  -41.17000 48.18800 1.000 83.11000  ? 86  SER A HG   1 
ATOM   1320 N  N    . ALA A 1 87  ? 35.50200  -37.53100 45.21100 1.000 52.06414  ? 87  ALA A N    1 
ATOM   1321 C  CA   . ALA A 1 87  ? 35.60400  -36.86400 43.91800 1.000 54.46442  ? 87  ALA A CA   1 
ATOM   1322 C  C    . ALA A 1 87  ? 36.81400  -35.94000 43.87000 1.000 56.12252  ? 87  ALA A C    1 
ATOM   1323 O  O    . ALA A 1 87  ? 37.51100  -35.87400 42.85100 1.000 54.67498  ? 87  ALA A O    1 
ATOM   1324 C  CB   . ALA A 1 87  ? 34.32200  -36.08300 43.63000 1.000 50.02968  ? 87  ALA A CB   1 
ATOM   1325 H  H    . ALA A 1 87  ? 34.83000  -37.28700 45.68900 1.000 62.59000  ? 87  ALA A H    1 
ATOM   1326 H  HA   . ALA A 1 87  ? 35.70900  -37.53500 43.22600 1.000 65.47000  ? 87  ALA A HA   1 
ATOM   1327 H  HB1  . ALA A 1 87  ? 34.40600  -35.64300 42.77000 1.000 60.15000  ? 87  ALA A HB1  1 
ATOM   1328 H  HB2  . ALA A 1 87  ? 33.57300  -36.70000 43.61400 1.000 60.15000  ? 87  ALA A HB2  1 
ATOM   1329 H  HB3  . ALA A 1 87  ? 34.19100  -35.42300 44.32800 1.000 60.15000  ? 87  ALA A HB3  1 
ATOM   1330 N  N    . LEU A 1 88  ? 37.07900  -35.22000 44.96200 1.000 57.10685  ? 88  LEU A N    1 
ATOM   1331 C  CA   . LEU A 1 88  ? 38.21800  -34.30800 44.98400 1.000 55.87512  ? 88  LEU A CA   1 
ATOM   1332 C  C    . LEU A 1 88  ? 39.52100  -35.04600 44.71100 1.000 55.98040  ? 88  LEU A C    1 
ATOM   1333 O  O    . LEU A 1 88  ? 40.42300  -34.50900 44.05700 1.000 58.68862  ? 88  LEU A O    1 
ATOM   1334 C  CB   . LEU A 1 88  ? 38.28700  -33.58600 46.32800 1.000 56.27517  ? 88  LEU A CB   1 
ATOM   1335 C  CG   . LEU A 1 88  ? 39.44300  -32.59800 46.49500 1.000 59.95719  ? 88  LEU A CG   1 
ATOM   1336 C  CD1  . LEU A 1 88  ? 39.43600  -31.56900 45.37400 1.000 57.80430  ? 88  LEU A CD1  1 
ATOM   1337 C  CD2  . LEU A 1 88  ? 39.37000  -31.91700 47.85100 1.000 61.91269  ? 88  LEU A CD2  1 
ATOM   1338 H  H    . LEU A 1 88  ? 36.62300  -35.24200 45.69000 1.000 68.64000  ? 88  LEU A H    1 
ATOM   1339 H  HA   . LEU A 1 88  ? 38.09700  -33.64100 44.28900 1.000 67.17000  ? 88  LEU A HA   1 
ATOM   1340 H  HB2  . LEU A 1 88  ? 37.46300  -33.08800 46.44800 1.000 67.64000  ? 88  LEU A HB2  1 
ATOM   1341 H  HB3  . LEU A 1 88  ? 38.37500  -34.25300 47.02700 1.000 67.64000  ? 88  LEU A HB3  1 
ATOM   1342 H  HG   . LEU A 1 88  ? 40.28100  -33.08300 46.44600 1.000 72.06000  ? 88  LEU A HG   1 
ATOM   1343 H  HD11 . LEU A 1 88  ? 40.06900  -30.86600 45.58700 1.000 69.48000  ? 88  LEU A HD11 1 
ATOM   1344 H  HD12 . LEU A 1 88  ? 39.69000  -32.00300 44.54500 1.000 69.48000  ? 88  LEU A HD12 1 
ATOM   1345 H  HD13 . LEU A 1 88  ? 38.54400  -31.19700 45.29200 1.000 69.48000  ? 88  LEU A HD13 1 
ATOM   1346 H  HD21 . LEU A 1 88  ? 40.11500  -31.30200 47.93600 1.000 74.41000  ? 88  LEU A HD21 1 
ATOM   1347 H  HD22 . LEU A 1 88  ? 38.53200  -31.43400 47.91700 1.000 74.41000  ? 88  LEU A HD22 1 
ATOM   1348 H  HD23 . LEU A 1 88  ? 39.41800  -32.59200 48.54600 1.000 74.41000  ? 88  LEU A HD23 1 
ATOM   1349 N  N    . ASN A 1 89  ? 39.64200  -36.28000 45.20600 1.000 58.89127  ? 89  ASN A N    1 
ATOM   1350 C  CA   . ASN A 1 89  ? 40.85400  -37.05400 44.96800 1.000 62.72857  ? 89  ASN A CA   1 
ATOM   1351 C  C    . ASN A 1 89  ? 41.11500  -37.26400 43.48300 1.000 57.35161  ? 89  ASN A C    1 
ATOM   1352 O  O    . ASN A 1 89  ? 42.26700  -37.48100 43.09300 1.000 65.05780  ? 89  ASN A O    1 
ATOM   1353 C  CB   . ASN A 1 89  ? 40.76500  -38.40700 45.67700 1.000 61.39420  ? 89  ASN A CB   1 
ATOM   1354 C  CG   . ASN A 1 89  ? 42.10400  -38.86600 46.22400 1.000 71.32171  ? 89  ASN A CG   1 
ATOM   1355 O  OD1  . ASN A 1 89  ? 42.84200  -38.08600 46.82500 1.000 73.99571  ? 89  ASN A OD1  1 
ATOM   1356 N  ND2  . ASN A 1 89  ? 42.42700  -40.13700 46.01200 1.000 73.99045  ? 89  ASN A ND2  1 
ATOM   1357 H  H    . ASN A 1 89  ? 39.04400  -36.68400 45.67500 1.000 70.78000  ? 89  ASN A H    1 
ATOM   1358 H  HA   . ASN A 1 89  ? 41.60900  -36.57200 45.34100 1.000 75.39000  ? 89  ASN A HA   1 
ATOM   1359 H  HB2  . ASN A 1 89  ? 40.14600  -38.33500 46.42000 1.000 73.79000  ? 89  ASN A HB2  1 
ATOM   1360 H  HB3  . ASN A 1 89  ? 40.45200  -39.07500 45.04700 1.000 73.79000  ? 89  ASN A HB3  1 
ATOM   1361 H  HD21 . ASN A 1 89  ? 43.17500  -40.44500 46.30200 1.000 88.90000  ? 89  ASN A HD21 1 
ATOM   1362 H  HD22 . ASN A 1 89  ? 41.88700  -40.65200 45.58300 1.000 88.90000  ? 89  ASN A HD22 1 
ATOM   1363 N  N    . HIS A 1 90  ? 40.07600  -37.20200 42.64900 1.000 56.43045  ? 90  HIS A N    1 
ATOM   1364 C  CA   . HIS A 1 90  ? 40.21000  -37.33800 41.20300 1.000 58.42279  ? 90  HIS A CA   1 
ATOM   1365 C  C    . HIS A 1 90  ? 40.29500  -35.98900 40.49800 1.000 55.23031  ? 90  HIS A C    1 
ATOM   1366 O  O    . HIS A 1 90  ? 41.15700  -35.79300 39.63600 1.000 60.28881  ? 90  HIS A O    1 
ATOM   1367 C  CB   . HIS A 1 90  ? 39.02700  -38.13200 40.63300 1.000 53.19059  ? 90  HIS A CB   1 
ATOM   1368 C  CG   . HIS A 1 90  ? 39.02300  -39.57800 41.01800 1.000 55.76984  ? 90  HIS A CG   1 
ATOM   1369 N  ND1  . HIS A 1 90  ? 38.18600  -40.08700 41.98900 1.000 54.86974  ? 90  HIS A ND1  1 
ATOM   1370 C  CD2  . HIS A 1 90  ? 39.74500  -40.62600 40.55700 1.000 57.97537  ? 90  HIS A CD2  1 
ATOM   1371 C  CE1  . HIS A 1 90  ? 38.39800  -41.38500 42.11300 1.000 52.40892  ? 90  HIS A CE1  1 
ATOM   1372 N  NE2  . HIS A 1 90  ? 39.33900  -41.73800 41.25600 1.000 65.97633  ? 90  HIS A NE2  1 
ATOM   1373 H  H    . HIS A 1 90  ? 39.26400  -37.07900 42.90600 1.000 67.83000  ? 90  HIS A H    1 
ATOM   1374 H  HA   . HIS A 1 90  ? 41.02400  -37.83100 41.01800 1.000 70.22000  ? 90  HIS A HA   1 
ATOM   1375 H  HB2  . HIS A 1 90  ? 38.20200  -37.73800 40.95800 1.000 63.94000  ? 90  HIS A HB2  1 
ATOM   1376 H  HB3  . HIS A 1 90  ? 39.05900  -38.08500 39.66500 1.000 63.94000  ? 90  HIS A HB3  1 
ATOM   1377 H  HD2  . HIS A 1 90  ? 40.39400  -40.59900 39.89100 1.000 69.68000  ? 90  HIS A HD2  1 
ATOM   1378 H  HE1  . HIS A 1 90  ? 37.95900  -41.95400 42.70400 1.000 63.00000  ? 90  HIS A HE1  1 
ATOM   1379 H  HE2  . HIS A 1 90  ? 39.64800  -42.53400 41.15200 1.000 79.29000  ? 90  HIS A HE2  1 
ATOM   1380 N  N    . THR A 1 91  ? 39.41100  -35.05100 40.84900 1.000 51.47986  ? 91  THR A N    1 
ATOM   1381 C  CA   . THR A 1 91  ? 39.37500  -33.77500 40.14400 1.000 54.92764  ? 91  THR A CA   1 
ATOM   1382 C  C    . THR A 1 91  ? 40.63200  -32.95400 40.39400 1.000 57.14369  ? 91  THR A C    1 
ATOM   1383 O  O    . THR A 1 91  ? 41.01500  -32.14100 39.54600 1.000 58.36752  ? 91  THR A O    1 
ATOM   1384 C  CB   . THR A 1 91  ? 38.13900  -32.97800 40.55800 1.000 55.81459  ? 91  THR A CB   1 
ATOM   1385 O  OG1  . THR A 1 91  ? 38.18700  -32.70400 41.96500 1.000 56.18305  ? 91  THR A OG1  1 
ATOM   1386 C  CG2  . THR A 1 91  ? 36.87400  -33.75600 40.23200 1.000 55.58298  ? 91  THR A CG2  1 
ATOM   1387 H  H    . THR A 1 91  ? 38.83300  -35.13000 41.48100 1.000 61.89000  ? 91  THR A H    1 
ATOM   1388 H  HA   . THR A 1 91  ? 39.31500  -33.95300 39.19300 1.000 66.03000  ? 91  THR A HA   1 
ATOM   1389 H  HB   . THR A 1 91  ? 38.11500  -32.13800 40.07200 1.000 67.09000  ? 91  THR A HB   1 
ATOM   1390 H  HG1  . THR A 1 91  ? 37.55000  -32.20200 42.18200 1.000 67.53000  ? 91  THR A HG1  1 
ATOM   1391 H  HG21 . THR A 1 91  ? 36.09200  -33.21100 40.41400 1.000 66.82000  ? 91  THR A HG21 1 
ATOM   1392 H  HG22 . THR A 1 91  ? 36.87100  -34.00700 39.29500 1.000 66.82000  ? 91  THR A HG22 1 
ATOM   1393 H  HG23 . THR A 1 91  ? 36.83000  -34.56000 40.77300 1.000 66.82000  ? 91  THR A HG23 1 
ATOM   1394 N  N    . LYS A 1 92  ? 41.28500  -33.14400 41.54100 1.000 57.82272  ? 92  LYS A N    1 
ATOM   1395 C  CA   . LYS A 1 92  ? 42.52300  -32.42200 41.80100 1.000 63.74185  ? 92  LYS A CA   1 
ATOM   1396 C  C    . LYS A 1 92  ? 43.64100  -32.86000 40.86400 1.000 63.98925  ? 92  LYS A C    1 
ATOM   1397 O  O    . LYS A 1 92  ? 44.65000  -32.15500 40.75100 1.000 69.03722  ? 92  LYS A O    1 
ATOM   1398 C  CB   . LYS A 1 92  ? 42.93900  -32.59800 43.26400 1.000 60.88098  ? 92  LYS A CB   1 
ATOM   1399 C  CG   . LYS A 1 92  ? 43.69800  -33.87500 43.57400 1.000 69.68730  ? 92  LYS A CG   1 
ATOM   1400 C  CD   . LYS A 1 92  ? 43.93700  -34.00600 45.07300 1.000 75.85910  ? 92  LYS A CD   1 
ATOM   1401 C  CE   . LYS A 1 92  ? 44.73900  -35.25400 45.40400 1.000 82.79151  ? 92  LYS A CE   1 
ATOM   1402 N  NZ   . LYS A 1 92  ? 44.48500  -35.72900 46.79300 1.000 78.68049  ? 92  LYS A NZ   1 
ATOM   1403 H  H    . LYS A 1 92  ? 41.03500  -33.67500 42.17100 1.000 69.50000  ? 92  LYS A H    1 
ATOM   1404 H  HA   . LYS A 1 92  ? 42.37700  -31.47300 41.65800 1.000 76.60000  ? 92  LYS A HA   1 
ATOM   1405 H  HB2  . LYS A 1 92  ? 43.51100  -31.85400 43.51000 1.000 73.17000  ? 92  LYS A HB2  1 
ATOM   1406 H  HB3  . LYS A 1 92  ? 42.13800  -32.59600 43.81100 1.000 73.17000  ? 92  LYS A HB3  1 
ATOM   1407 H  HG2  . LYS A 1 92  ? 43.18100  -34.64000 43.27600 1.000 83.74000  ? 92  LYS A HG2  1 
ATOM   1408 H  HG3  . LYS A 1 92  ? 44.55700  -33.85900 43.12500 1.000 83.74000  ? 92  LYS A HG3  1 
ATOM   1409 H  HD2  . LYS A 1 92  ? 44.43200  -33.23400 45.38800 1.000 91.14000  ? 92  LYS A HD2  1 
ATOM   1410 H  HD3  . LYS A 1 92  ? 43.08400  -34.06200 45.53000 1.000 91.14000  ? 92  LYS A HD3  1 
ATOM   1411 H  HE2  . LYS A 1 92  ? 44.49100  -35.96400 44.79100 1.000 99.46000  ? 92  LYS A HE2  1 
ATOM   1412 H  HE3  . LYS A 1 92  ? 45.68500  -35.05800 45.31900 1.000 99.46000  ? 92  LYS A HE3  1 
ATOM   1413 H  HZ1  . LYS A 1 92  ? 43.62100  -35.91500 46.89800 1.000 94.53000  ? 92  LYS A HZ1  1 
ATOM   1414 H  HZ2  . LYS A 1 92  ? 44.71800  -35.09900 47.37700 1.000 94.53000  ? 92  LYS A HZ2  1 
ATOM   1415 H  HZ3  . LYS A 1 92  ? 44.96000  -36.46400 46.95500 1.000 94.53000  ? 92  LYS A HZ3  1 
ATOM   1416 N  N    . LYS A 1 93  ? 43.48300  -33.99900 40.18700 1.000 60.37040  ? 93  LYS A N    1 
ATOM   1417 C  CA   . LYS A 1 93  ? 44.43100  -34.42400 39.16700 1.000 65.21835  ? 93  LYS A CA   1 
ATOM   1418 C  C    . LYS A 1 93  ? 44.06400  -33.92400 37.77500 1.000 60.94941  ? 93  LYS A C    1 
ATOM   1419 O  O    . LYS A 1 93  ? 44.91600  -33.94800 36.88000 1.000 63.86292  ? 93  LYS A O    1 
ATOM   1420 C  CB   . LYS A 1 93  ? 44.53300  -35.95300 39.13800 1.000 66.35796  ? 93  LYS A CB   1 
ATOM   1421 C  CG   . LYS A 1 93  ? 44.79400  -36.59600 40.49500 1.000 74.40629  ? 93  LYS A CG   1 
ATOM   1422 C  CD   . LYS A 1 93  ? 46.16100  -36.21600 41.04500 1.000 85.62606  ? 93  LYS A CD   1 
ATOM   1423 C  CE   . LYS A 1 93  ? 46.61300  -37.18100 42.13200 1.000 93.78493  ? 93  LYS A CE   1 
ATOM   1424 N  NZ   . LYS A 1 93  ? 47.21900  -36.47500 43.29700 1.000 106.41276 ? 93  LYS A NZ   1 
ATOM   1425 H  H    . LYS A 1 93  ? 42.82800  -34.54400 40.30400 1.000 72.56000  ? 93  LYS A H    1 
ATOM   1426 H  HA   . LYS A 1 93  ? 45.30700  -34.07200 39.39300 1.000 78.38000  ? 93  LYS A HA   1 
ATOM   1427 H  HB2  . LYS A 1 93  ? 43.69800  -36.31200 38.80000 1.000 79.74000  ? 93  LYS A HB2  1 
ATOM   1428 H  HB3  . LYS A 1 93  ? 45.26400  -36.20300 38.55100 1.000 79.74000  ? 93  LYS A HB3  1 
ATOM   1429 H  HG2  . LYS A 1 93  ? 44.11900  -36.29700 41.12500 1.000 89.40000  ? 93  LYS A HG2  1 
ATOM   1430 H  HG3  . LYS A 1 93  ? 44.76000  -37.56100 40.40400 1.000 89.40000  ? 93  LYS A HG3  1 
ATOM   1431 H  HD2  . LYS A 1 93  ? 46.81300  -36.23800 40.32800 1.000 102.86000 ? 93  LYS A HD2  1 
ATOM   1432 H  HD3  . LYS A 1 93  ? 46.11800  -35.32600 41.42700 1.000 102.86000 ? 93  LYS A HD3  1 
ATOM   1433 H  HE2  . LYS A 1 93  ? 45.84700  -37.68400 42.45000 1.000 112.65000 ? 93  LYS A HE2  1 
ATOM   1434 H  HE3  . LYS A 1 93  ? 47.27800  -37.78500 41.76600 1.000 112.65000 ? 93  LYS A HE3  1 
ATOM   1435 H  HZ1  . LYS A 1 93  ? 47.45600  -37.06400 43.92000 1.000 127.81000 ? 93  LYS A HZ1  1 
ATOM   1436 H  HZ2  . LYS A 1 93  ? 47.94100  -36.02400 43.03700 1.000 127.81000 ? 93  LYS A HZ2  1 
ATOM   1437 H  HZ3  . LYS A 1 93  ? 46.63200  -35.90400 43.64600 1.000 127.81000 ? 93  LYS A HZ3  1 
ATOM   1438 N  N    . TRP A 1 94  ? 42.82800  -33.47400 37.57200 1.000 60.11247  ? 94  TRP A N    1 
ATOM   1439 C  CA   . TRP A 1 94  ? 42.40500  -32.98500 36.26900 1.000 58.76494  ? 94  TRP A CA   1 
ATOM   1440 C  C    . TRP A 1 94  ? 43.15400  -31.70400 35.90500 1.000 62.04165  ? 94  TRP A C    1 
ATOM   1441 O  O    . TRP A 1 94  ? 43.76600  -31.04500 36.74900 1.000 64.40772  ? 94  TRP A O    1 
ATOM   1442 C  CB   . TRP A 1 94  ? 40.89800  -32.72000 36.25500 1.000 54.34862  ? 94  TRP A CB   1 
ATOM   1443 C  CG   . TRP A 1 94  ? 40.04900  -33.95800 36.33700 1.000 55.63299  ? 94  TRP A CG   1 
ATOM   1444 C  CD1  . TRP A 1 94  ? 40.48100  -35.25300 36.34000 1.000 57.07263  ? 94  TRP A CD1  1 
ATOM   1445 C  CD2  . TRP A 1 94  ? 38.61900  -34.01300 36.42700 1.000 46.62138  ? 94  TRP A CD2  1 
ATOM   1446 N  NE1  . TRP A 1 94  ? 39.41000  -36.10900 36.42700 1.000 57.27792  ? 94  TRP A NE1  1 
ATOM   1447 C  CE2  . TRP A 1 94  ? 38.25500  -35.37300 36.48200 1.000 44.41585  ? 94  TRP A CE2  1 
ATOM   1448 C  CE3  . TRP A 1 94  ? 37.61100  -33.04400 36.46600 1.000 48.29526  ? 94  TRP A CE3  1 
ATOM   1449 C  CZ2  . TRP A 1 94  ? 36.92800  -35.78800 36.57300 1.000 45.55020  ? 94  TRP A CZ2  1 
ATOM   1450 C  CZ3  . TRP A 1 94  ? 36.29300  -33.45900 36.55700 1.000 44.81853  ? 94  TRP A CZ3  1 
ATOM   1451 C  CH2  . TRP A 1 94  ? 35.96400  -34.81800 36.61000 1.000 41.55498  ? 94  TRP A CH2  1 
ATOM   1452 H  H    . TRP A 1 94  ? 42.21600  -33.44300 38.17500 1.000 72.25000  ? 94  TRP A H    1 
ATOM   1453 H  HA   . TRP A 1 94  ? 42.60300  -33.65800 35.59900 1.000 70.63000  ? 94  TRP A HA   1 
ATOM   1454 H  HB2  . TRP A 1 94  ? 40.67500  -32.16100 37.01600 1.000 65.33000  ? 94  TRP A HB2  1 
ATOM   1455 H  HB3  . TRP A 1 94  ? 40.67200  -32.26300 35.43000 1.000 65.33000  ? 94  TRP A HB3  1 
ATOM   1456 H  HD1  . TRP A 1 94  ? 41.37200  -35.51700 36.29000 1.000 68.60000  ? 94  TRP A HD1  1 
ATOM   1457 H  HE1  . TRP A 1 94  ? 39.45600  -36.96800 36.44400 1.000 68.84000  ? 94  TRP A HE1  1 
ATOM   1458 H  HE3  . TRP A 1 94  ? 37.82200  -32.13900 36.43100 1.000 58.07000  ? 94  TRP A HE3  1 
ATOM   1459 H  HZ2  . TRP A 1 94  ? 36.70600  -36.69100 36.60800 1.000 54.77000  ? 94  TRP A HZ2  1 
ATOM   1460 H  HZ3  . TRP A 1 94  ? 35.61400  -32.82300 36.58400 1.000 53.89000  ? 94  TRP A HZ3  1 
ATOM   1461 H  HH2  . TRP A 1 94  ? 35.07000  -35.06700 36.67100 1.000 49.98000  ? 94  TRP A HH2  1 
ATOM   1462 N  N    . LYS A 1 95  ? 43.09500  -31.35700 34.62200 1.000 59.28606  ? 95  LYS A N    1 
ATOM   1463 C  CA   . LYS A 1 95  ? 43.68200  -30.13000 34.10200 1.000 58.21751  ? 95  LYS A CA   1 
ATOM   1464 C  C    . LYS A 1 95  ? 42.57100  -29.14900 33.75200 1.000 54.35915  ? 95  LYS A C    1 
ATOM   1465 O  O    . LYS A 1 95  ? 41.50900  -29.55000 33.26500 1.000 55.82511  ? 95  LYS A O    1 
ATOM   1466 C  CB   . LYS A 1 95  ? 44.54500  -30.40900 32.86900 1.000 62.18640  ? 95  LYS A CB   1 
ATOM   1467 C  CG   . LYS A 1 95  ? 45.67400  -31.40300 33.10900 1.000 65.26309  ? 95  LYS A CG   1 
ATOM   1468 C  CD   . LYS A 1 95  ? 46.70500  -30.86400 34.09000 1.000 71.64017  ? 95  LYS A CD   1 
ATOM   1469 C  CE   . LYS A 1 95  ? 47.85600  -31.84100 34.27700 1.000 78.63311  ? 95  LYS A CE   1 
ATOM   1470 N  NZ   . LYS A 1 95  ? 48.86100  -31.34800 35.26000 1.000 88.36323  ? 95  LYS A NZ   1 
ATOM   1471 H  H    . LYS A 1 95  ? 42.70800  -31.83100 34.01700 1.000 71.26000  ? 95  LYS A H    1 
ATOM   1472 H  HA   . LYS A 1 95  ? 44.25000  -29.72500 34.77600 1.000 69.98000  ? 95  LYS A HA   1 
ATOM   1473 H  HB2  . LYS A 1 95  ? 43.97900  -30.77100 32.16900 1.000 74.74000  ? 95  LYS A HB2  1 
ATOM   1474 H  HB3  . LYS A 1 95  ? 44.94500  -29.57600 32.57400 1.000 74.74000  ? 95  LYS A HB3  1 
ATOM   1475 H  HG2  . LYS A 1 95  ? 45.30600  -32.22200 33.47600 1.000 78.43000  ? 95  LYS A HG2  1 
ATOM   1476 H  HG3  . LYS A 1 95  ? 46.12200  -31.58800 32.26900 1.000 78.43000  ? 95  LYS A HG3  1 
ATOM   1477 H  HD2  . LYS A 1 95  ? 47.06500  -30.02900 33.75200 1.000 86.08000  ? 95  LYS A HD2  1 
ATOM   1478 H  HD3  . LYS A 1 95  ? 46.28500  -30.71900 34.95200 1.000 86.08000  ? 95  LYS A HD3  1 
ATOM   1479 H  HE2  . LYS A 1 95  ? 47.50700  -32.68600 34.60000 1.000 94.47000  ? 95  LYS A HE2  1 
ATOM   1480 H  HE3  . LYS A 1 95  ? 48.30500  -31.97000 33.42600 1.000 94.47000  ? 95  LYS A HE3  1 
ATOM   1481 H  HZ1  . LYS A 1 95  ? 49.51900  -31.94100 35.34700 1.000 106.15000 ? 95  LYS A HZ1  1 
ATOM   1482 H  HZ2  . LYS A 1 95  ? 49.20400  -30.57400 34.98400 1.000 106.15000 ? 95  LYS A HZ2  1 
ATOM   1483 H  HZ3  . LYS A 1 95  ? 48.47600  -31.22600 36.05400 1.000 106.15000 ? 95  LYS A HZ3  1 
ATOM   1484 N  N    . TYR A 1 96  ? 42.81900  -27.86300 34.00100 1.000 55.47244  ? 96  TYR A N    1 
ATOM   1485 C  CA   . TYR A 1 96  ? 41.82300  -26.80700 33.82000 1.000 55.90407  ? 96  TYR A CA   1 
ATOM   1486 C  C    . TYR A 1 96  ? 42.44600  -25.66900 33.02300 1.000 59.62031  ? 96  TYR A C    1 
ATOM   1487 O  O    . TYR A 1 96  ? 42.82500  -24.63200 33.58500 1.000 61.61791  ? 96  TYR A O    1 
ATOM   1488 C  CB   . TYR A 1 96  ? 41.29900  -26.31500 35.17000 1.000 55.88828  ? 96  TYR A CB   1 
ATOM   1489 C  CG   . TYR A 1 96  ? 40.76400  -27.43000 36.03400 1.000 53.98279  ? 96  TYR A CG   1 
ATOM   1490 C  CD1  . TYR A 1 96  ? 39.47400  -27.90900 35.85700 1.000 49.86914  ? 96  TYR A CD1  1 
ATOM   1491 C  CD2  . TYR A 1 96  ? 41.55200  -28.01400 37.01800 1.000 51.95886  ? 96  TYR A CD2  1 
ATOM   1492 C  CE1  . TYR A 1 96  ? 38.98000  -28.93100 36.63900 1.000 50.02442  ? 96  TYR A CE1  1 
ATOM   1493 C  CE2  . TYR A 1 96  ? 41.06500  -29.03800 37.80500 1.000 52.77212  ? 96  TYR A CE2  1 
ATOM   1494 C  CZ   . TYR A 1 96  ? 39.77800  -29.49300 37.61000 1.000 50.60080  ? 96  TYR A CZ   1 
ATOM   1495 O  OH   . TYR A 1 96  ? 39.28500  -30.51400 38.38700 1.000 53.29060  ? 96  TYR A OH   1 
ATOM   1496 H  H    . TYR A 1 96  ? 43.57700  -27.57100 34.28400 1.000 66.68000  ? 96  TYR A H    1 
ATOM   1497 H  HA   . TYR A 1 96  ? 41.08000  -27.15700 33.30400 1.000 67.19000  ? 96  TYR A HA   1 
ATOM   1498 H  HB2  . TYR A 1 96  ? 42.02300  -25.88400 35.65100 1.000 67.18000  ? 96  TYR A HB2  1 
ATOM   1499 H  HB3  . TYR A 1 96  ? 40.58000  -25.68300 35.01700 1.000 67.18000  ? 96  TYR A HB3  1 
ATOM   1500 H  HD1  . TYR A 1 96  ? 38.93400  -27.53400 35.20000 1.000 59.96000  ? 96  TYR A HD1  1 
ATOM   1501 H  HD2  . TYR A 1 96  ? 42.42100  -27.71000 37.14800 1.000 62.46000  ? 96  TYR A HD2  1 
ATOM   1502 H  HE1  . TYR A 1 96  ? 38.11200  -29.24000 36.51100 1.000 60.14000  ? 96  TYR A HE1  1 
ATOM   1503 H  HE2  . TYR A 1 96  ? 41.60200  -29.41900 38.46300 1.000 63.44000  ? 96  TYR A HE2  1 
ATOM   1504 H  HH   . TYR A 1 96  ? 39.87600  -30.77900 38.92200 1.000 64.06000  ? 96  TYR A HH   1 
ATOM   1505 N  N    . PRO A 1 97  ? 42.55500  -25.82200 31.70700 1.000 56.60416  ? 97  PRO A N    1 
ATOM   1506 C  CA   . PRO A 1 97  ? 43.17000  -24.77400 30.89100 1.000 62.47854  ? 97  PRO A CA   1 
ATOM   1507 C  C    . PRO A 1 97  ? 42.19700  -23.64300 30.59600 1.000 59.44660  ? 97  PRO A C    1 
ATOM   1508 O  O    . PRO A 1 97  ? 40.97600  -23.79800 30.65100 1.000 55.83827  ? 97  PRO A O    1 
ATOM   1509 C  CB   . PRO A 1 97  ? 43.56400  -25.50600 29.60200 1.000 63.85766  ? 97  PRO A CB   1 
ATOM   1510 C  CG   . PRO A 1 97  ? 42.69900  -26.74500 29.55500 1.000 62.50486  ? 97  PRO A CG   1 
ATOM   1511 C  CD   . PRO A 1 97  ? 41.99800  -26.90800 30.88200 1.000 50.94032  ? 97  PRO A CD   1 
ATOM   1512 H  HA   . PRO A 1 97  ? 43.96300  -24.42200 31.32200 1.000 75.09000  ? 97  PRO A HA   1 
ATOM   1513 H  HB2  . PRO A 1 97  ? 43.39100  -24.93600 28.83600 1.000 76.74000  ? 97  PRO A HB2  1 
ATOM   1514 H  HB3  . PRO A 1 97  ? 44.50400  -25.74200 29.63400 1.000 76.74000  ? 97  PRO A HB3  1 
ATOM   1515 H  HG2  . PRO A 1 97  ? 42.04600  -26.64500 28.84500 1.000 75.12000  ? 97  PRO A HG2  1 
ATOM   1516 H  HG3  . PRO A 1 97  ? 43.26300  -27.51400 29.38100 1.000 75.12000  ? 97  PRO A HG3  1 
ATOM   1517 H  HD2  . PRO A 1 97  ? 41.03900  -26.80500 30.77900 1.000 61.24000  ? 97  PRO A HD2  1 
ATOM   1518 H  HD3  . PRO A 1 97  ? 42.19800  -27.77300 31.27200 1.000 61.24000  ? 97  PRO A HD3  1 
ATOM   1519 N  N    . GLN A 1 98  ? 42.77100  -22.48700 30.28200 1.000 63.42603  ? 98  GLN A N    1 
ATOM   1520 C  CA   . GLN A 1 98  ? 42.00200  -21.32600 29.85200 1.000 60.54937  ? 98  GLN A CA   1 
ATOM   1521 C  C    . GLN A 1 98  ? 41.78100  -21.43700 28.34800 1.000 55.64615  ? 98  GLN A C    1 
ATOM   1522 O  O    . GLN A 1 98  ? 42.73300  -21.34100 27.56700 1.000 57.67534  ? 98  GLN A O    1 
ATOM   1523 C  CB   . GLN A 1 98  ? 42.72800  -20.03200 30.20700 1.000 63.48656  ? 98  GLN A CB   1 
ATOM   1524 C  CG   . GLN A 1 98  ? 42.85700  -19.78300 31.69800 1.000 65.15781  ? 98  GLN A CG   1 
ATOM   1525 C  CD   . GLN A 1 98  ? 41.51100  -19.66300 32.38600 1.000 58.21751  ? 98  GLN A CD   1 
ATOM   1526 O  OE1  . GLN A 1 98  ? 40.70900  -18.78900 32.05600 1.000 59.46502  ? 98  GLN A OE1  1 
ATOM   1527 N  NE2  . GLN A 1 98  ? 41.25400  -20.54800 33.34100 1.000 55.45928  ? 98  GLN A NE2  1 
ATOM   1528 H  H    . GLN A 1 98  ? 43.61900  -22.34800 30.31100 1.000 76.23000  ? 98  GLN A H    1 
ATOM   1529 H  HA   . GLN A 1 98  ? 41.14100  -21.31900 30.29800 1.000 72.77000  ? 98  GLN A HA   1 
ATOM   1530 H  HB2  . GLN A 1 98  ? 43.62300  -20.06600 29.83500 1.000 76.30000  ? 98  GLN A HB2  1 
ATOM   1531 H  HB3  . GLN A 1 98  ? 42.23900  -19.28600 29.82500 1.000 76.30000  ? 98  GLN A HB3  1 
ATOM   1532 H  HG2  . GLN A 1 98  ? 43.33700  -20.52300 32.10300 1.000 78.30000  ? 98  GLN A HG2  1 
ATOM   1533 H  HG3  . GLN A 1 98  ? 43.34300  -18.95600 31.84100 1.000 78.30000  ? 98  GLN A HG3  1 
ATOM   1534 H  HE21 . GLN A 1 98  ? 41.83700  -21.14800 33.54000 1.000 66.67000  ? 98  GLN A HE21 1 
ATOM   1535 H  HE22 . GLN A 1 98  ? 40.50400  -20.52200 33.76100 1.000 66.67000  ? 98  GLN A HE22 1 
ATOM   1536 N  N    . VAL A 1 99  ? 40.53300  -21.64600 27.94400 1.000 54.04332  ? 99  VAL A N    1 
ATOM   1537 C  CA   . VAL A 1 99  ? 40.15900  -21.74400 26.53800 1.000 53.78540  ? 99  VAL A CA   1 
ATOM   1538 C  C    . VAL A 1 99  ? 39.34000  -20.50700 26.19700 1.000 52.14573  ? 99  VAL A C    1 
ATOM   1539 O  O    . VAL A 1 99  ? 38.22700  -20.32600 26.70600 1.000 46.70034  ? 99  VAL A O    1 
ATOM   1540 C  CB   . VAL A 1 99  ? 39.37700  -23.03000 26.23900 1.000 52.36154  ? 99  VAL A CB   1 
ATOM   1541 C  CG1  . VAL A 1 99  ? 39.09900  -23.14300 24.74600 1.000 50.04284  ? 99  VAL A CG1  1 
ATOM   1542 C  CG2  . VAL A 1 99  ? 40.14400  -24.24600 26.73800 1.000 52.16152  ? 99  VAL A CG2  1 
ATOM   1543 H  H    . VAL A 1 99  ? 39.86700  -21.73700 28.48100 1.000 64.96000  ? 99  VAL A H    1 
ATOM   1544 H  HA   . VAL A 1 99  ? 40.96100  -21.74300 25.99300 1.000 64.66000  ? 99  VAL A HA   1 
ATOM   1545 H  HB   . VAL A 1 99  ? 38.52700  -22.99900 26.70500 1.000 62.95000  ? 99  VAL A HB   1 
ATOM   1546 H  HG11 . VAL A 1 99  ? 38.75300  -24.02900 24.55600 1.000 60.17000  ? 99  VAL A HG11 1 
ATOM   1547 H  HG12 . VAL A 1 99  ? 38.44500  -22.47200 24.49500 1.000 60.17000  ? 99  VAL A HG12 1 
ATOM   1548 H  HG13 . VAL A 1 99  ? 39.92500  -22.99900 24.25900 1.000 60.17000  ? 99  VAL A HG13 1 
ATOM   1549 H  HG21 . VAL A 1 99  ? 39.67300  -25.04900 26.46600 1.000 62.71000  ? 99  VAL A HG21 1 
ATOM   1550 H  HG22 . VAL A 1 99  ? 41.03400  -24.23800 26.35100 1.000 62.71000  ? 99  VAL A HG22 1 
ATOM   1551 H  HG23 . VAL A 1 99  ? 40.20300  -24.20700 27.70500 1.000 62.71000  ? 99  VAL A HG23 1 
ATOM   1552 N  N    . ASN A 1 100 ? 39.89300  -19.65400 25.33500 1.000 51.78779  ? 100 ASN A N    1 
ATOM   1553 C  CA   . ASN A 1 100 ? 39.23100  -18.42000 24.91600 1.000 54.13017  ? 100 ASN A CA   1 
ATOM   1554 C  C    . ASN A 1 100 ? 38.78800  -17.59300 26.11900 1.000 52.97214  ? 100 ASN A C    1 
ATOM   1555 O  O    . ASN A 1 100 ? 37.69600  -17.02100 26.14000 1.000 51.62987  ? 100 ASN A O    1 
ATOM   1556 C  CB   . ASN A 1 100 ? 38.04200  -18.72100 24.00300 1.000 54.68024  ? 100 ASN A CB   1 
ATOM   1557 C  CG   . ASN A 1 100 ? 37.59200  -17.50500 23.21900 1.000 55.69615  ? 100 ASN A CG   1 
ATOM   1558 O  OD1  . ASN A 1 100 ? 38.40700  -16.67600 22.81800 1.000 55.10398  ? 100 ASN A OD1  1 
ATOM   1559 N  ND2  . ASN A 1 100 ? 36.28800  -17.38800 23.00500 1.000 62.21799  ? 100 ASN A ND2  1 
ATOM   1560 H  H    . ASN A 1 100 ? 40.66500  -19.77000 24.97400 1.000 62.25000  ? 100 ASN A H    1 
ATOM   1561 H  HA   . ASN A 1 100 ? 39.87200  -17.89100 24.41500 1.000 65.07000  ? 100 ASN A HA   1 
ATOM   1562 H  HB2  . ASN A 1 100 ? 38.29500  -19.41100 23.37000 1.000 65.73000  ? 100 ASN A HB2  1 
ATOM   1563 H  HB3  . ASN A 1 100 ? 37.29600  -19.02300 24.54400 1.000 65.73000  ? 100 ASN A HB3  1 
ATOM   1564 H  HD21 . ASN A 1 100 ? 35.98300  -16.71500 22.56500 1.000 74.77000  ? 100 ASN A HD21 1 
ATOM   1565 H  HD22 . ASN A 1 100 ? 35.74700  -17.98500 23.30800 1.000 74.77000  ? 100 ASN A HD22 1 
ATOM   1566 N  N    . GLY A 1 101 ? 39.64600  -17.53000 27.13500 1.000 53.59064  ? 101 GLY A N    1 
ATOM   1567 C  CA   . GLY A 1 101 ? 39.37300  -16.73600 28.31200 1.000 49.26907  ? 101 GLY A CA   1 
ATOM   1568 C  C    . GLY A 1 101 ? 38.50500  -17.40000 29.35600 1.000 53.05899  ? 101 GLY A C    1 
ATOM   1569 O  O    . GLY A 1 101 ? 38.29400  -16.81100 30.42400 1.000 50.85083  ? 101 GLY A O    1 
ATOM   1570 H  H    . GLY A 1 101 ? 40.39800  -17.94600 27.16000 1.000 64.42000  ? 101 GLY A H    1 
ATOM   1571 H  HA2  . GLY A 1 101 ? 40.21700  -16.50900 28.73300 1.000 59.24000  ? 101 GLY A HA2  1 
ATOM   1572 H  HA3  . GLY A 1 101 ? 38.92900  -15.91900 28.03700 1.000 59.24000  ? 101 GLY A HA3  1 
ATOM   1573 N  N    . LEU A 1 102 ? 37.99400  -18.59700 29.08900 1.000 51.50618  ? 102 LEU A N    1 
ATOM   1574 C  CA   . LEU A 1 102 ? 37.15000  -19.32300 30.02400 1.000 49.34013  ? 102 LEU A CA   1 
ATOM   1575 C  C    . LEU A 1 102 ? 37.89300  -20.53700 30.56400 1.000 51.80884  ? 102 LEU A C    1 
ATOM   1576 O  O    . LEU A 1 102 ? 38.69800  -21.15600 29.86200 1.000 52.08782  ? 102 LEU A O    1 
ATOM   1577 C  CB   . LEU A 1 102 ? 35.84900  -19.78000 29.35500 1.000 52.74843  ? 102 LEU A CB   1 
ATOM   1578 C  CG   . LEU A 1 102 ? 34.97900  -18.69300 28.72400 1.000 52.82475  ? 102 LEU A CG   1 
ATOM   1579 C  CD1  . LEU A 1 102 ? 33.88900  -19.32100 27.86800 1.000 55.34085  ? 102 LEU A CD1  1 
ATOM   1580 C  CD2  . LEU A 1 102 ? 34.37100  -17.80300 29.79100 1.000 53.22217  ? 102 LEU A CD2  1 
ATOM   1581 H  H    . LEU A 1 102 ? 38.12700  -19.01900 28.35200 1.000 61.92000  ? 102 LEU A H    1 
ATOM   1582 H  HA   . LEU A 1 102 ? 36.92300  -18.74300 30.76700 1.000 59.32000  ? 102 LEU A HA   1 
ATOM   1583 H  HB2  . LEU A 1 102 ? 36.07900  -20.40500 28.64900 1.000 63.41000  ? 102 LEU A HB2  1 
ATOM   1584 H  HB3  . LEU A 1 102 ? 35.30700  -20.22300 30.02600 1.000 63.41000  ? 102 LEU A HB3  1 
ATOM   1585 H  HG   . LEU A 1 102 ? 35.53200  -18.13600 28.15400 1.000 63.50000  ? 102 LEU A HG   1 
ATOM   1586 H  HD11 . LEU A 1 102 ? 33.33700  -18.61700 27.49400 1.000 66.52000  ? 102 LEU A HD11 1 
ATOM   1587 H  HD12 . LEU A 1 102 ? 34.30300  -19.83200 27.15500 1.000 66.52000  ? 102 LEU A HD12 1 
ATOM   1588 H  HD13 . LEU A 1 102 ? 33.34900  -19.90500 28.42400 1.000 66.52000  ? 102 LEU A HD13 1 
ATOM   1589 H  HD21 . LEU A 1 102 ? 33.83400  -17.11800 29.36200 1.000 63.98000  ? 102 LEU A HD21 1 
ATOM   1590 H  HD22 . LEU A 1 102 ? 33.81500  -18.34300 30.37300 1.000 63.98000  ? 102 LEU A HD22 1 
ATOM   1591 H  HD23 . LEU A 1 102 ? 35.08500  -17.39100 30.30200 1.000 63.98000  ? 102 LEU A HD23 1 
ATOM   1592 N  N    . THR A 1 103 ? 37.61600  -20.87200 31.82200 1.000 49.92704  ? 103 THR A N    1 
ATOM   1593 C  CA   . THR A 1 103 ? 38.16500  -22.07800 32.42700 1.000 46.37398  ? 103 THR A CA   1 
ATOM   1594 C  C    . THR A 1 103 ? 37.37500  -23.28700 31.93800 1.000 49.72701  ? 103 THR A C    1 
ATOM   1595 O  O    . THR A 1 103 ? 36.15800  -23.36500 32.14400 1.000 49.62700  ? 103 THR A O    1 
ATOM   1596 C  CB   . THR A 1 103 ? 38.11800  -21.99200 33.95200 1.000 53.74592  ? 103 THR A CB   1 
ATOM   1597 O  OG1  . THR A 1 103 ? 38.78900  -20.80500 34.39500 1.000 50.59817  ? 103 THR A OG1  1 
ATOM   1598 C  CG2  . THR A 1 103 ? 38.78700  -23.21000 34.57500 1.000 49.79544  ? 103 THR A CG2  1 
ATOM   1599 H  H    . THR A 1 103 ? 37.11000  -20.41500 32.34700 1.000 60.03000  ? 103 THR A H    1 
ATOM   1600 H  HA   . THR A 1 103 ? 39.09300  -22.17600 32.16100 1.000 55.76000  ? 103 THR A HA   1 
ATOM   1601 H  HB   . THR A 1 103 ? 37.19300  -21.96500 34.24300 1.000 64.61000  ? 103 THR A HB   1 
ATOM   1602 H  HG1  . THR A 1 103 ? 38.73700  -20.74100 35.23100 1.000 60.83000  ? 103 THR A HG1  1 
ATOM   1603 H  HG21 . THR A 1 103 ? 38.87400  -23.08700 35.53400 1.000 59.87000  ? 103 THR A HG21 1 
ATOM   1604 H  HG22 . THR A 1 103 ? 38.25600  -24.00400 34.40600 1.000 59.87000  ? 103 THR A HG22 1 
ATOM   1605 H  HG23 . THR A 1 103 ? 39.67000  -23.33500 34.19300 1.000 59.87000  ? 103 THR A HG23 1 
ATOM   1606 N  N    . SER A 1 104 ? 38.06100  -24.22200 31.28900 1.000 47.85574  ? 104 SER A N    1 
ATOM   1607 C  CA   . SER A 1 104 ? 37.47200  -25.46900 30.83200 1.000 48.26631  ? 104 SER A CA   1 
ATOM   1608 C  C    . SER A 1 104 ? 38.04300  -26.63000 31.64600 1.000 49.44540  ? 104 SER A C    1 
ATOM   1609 O  O    . SER A 1 104 ? 38.69500  -26.43300 32.67900 1.000 51.30352  ? 104 SER A O    1 
ATOM   1610 C  CB   . SER A 1 104 ? 37.72500  -25.65300 29.33400 1.000 49.54015  ? 104 SER A CB   1 
ATOM   1611 O  OG   . SER A 1 104 ? 36.92400  -26.69800 28.80800 1.000 48.23473  ? 104 SER A OG   1 
ATOM   1612 H  H    . SER A 1 104 ? 38.89700  -24.15100 31.09600 1.000 57.54000  ? 104 SER A H    1 
ATOM   1613 H  HA   . SER A 1 104 ? 36.51400  -25.43200 30.97400 1.000 58.03000  ? 104 SER A HA   1 
ATOM   1614 H  HB2  . SER A 1 104 ? 37.50700  -24.82700 28.87400 1.000 59.56000  ? 104 SER A HB2  1 
ATOM   1615 H  HB3  . SER A 1 104 ? 38.66000  -25.87300 29.19600 1.000 59.56000  ? 104 SER A HB3  1 
ATOM   1616 H  HG   . SER A 1 104 ? 37.07400  -26.79000 27.98700 1.000 58.00000  ? 104 SER A HG   1 
ATOM   1617 N  N    . ILE A 1 105 ? 37.79100  -27.85000 31.17700 1.000 47.94785  ? 105 ILE A N    1 
ATOM   1618 C  CA   . ILE A 1 105 ? 38.34200  -29.05800 31.78300 1.000 48.27158  ? 105 ILE A CA   1 
ATOM   1619 C  C    . ILE A 1 105 ? 38.82600  -29.97200 30.66700 1.000 51.53776  ? 105 ILE A C    1 
ATOM   1620 O  O    . ILE A 1 105 ? 38.06300  -30.29900 29.75100 1.000 51.78779  ? 105 ILE A O    1 
ATOM   1621 C  CB   . ILE A 1 105 ? 37.31500  -29.80500 32.65900 1.000 46.01604  ? 105 ILE A CB   1 
ATOM   1622 C  CG1  . ILE A 1 105 ? 36.47000  -28.83000 33.48000 1.000 41.84975  ? 105 ILE A CG1  1 
ATOM   1623 C  CG2  . ILE A 1 105 ? 38.02700  -30.79100 33.57800 1.000 49.15063  ? 105 ILE A CG2  1 
ATOM   1624 C  CD1  . ILE A 1 105 ? 35.36000  -29.50700 34.26300 1.000 42.95515  ? 105 ILE A CD1  1 
ATOM   1625 H  H    . ILE A 1 105 ? 37.29300  -28.00600 30.49300 1.000 57.65000  ? 105 ILE A H    1 
ATOM   1626 H  HA   . ILE A 1 105 ? 39.09300  -28.80700 32.34200 1.000 58.04000  ? 105 ILE A HA   1 
ATOM   1627 H  HB   . ILE A 1 105 ? 36.72000  -30.29100 32.06800 1.000 55.33000  ? 105 ILE A HB   1 
ATOM   1628 H  HG12 . ILE A 1 105 ? 37.04500  -28.37400 34.11300 1.000 50.33000  ? 105 ILE A HG12 1 
ATOM   1629 H  HG13 . ILE A 1 105 ? 36.06200  -28.18700 32.87900 1.000 50.33000  ? 105 ILE A HG13 1 
ATOM   1630 H  HG21 . ILE A 1 105 ? 37.36500  -31.33800 34.02800 1.000 59.09000  ? 105 ILE A HG21 1 
ATOM   1631 H  HG22 . ILE A 1 105 ? 38.61400  -31.35200 33.04600 1.000 59.09000  ? 105 ILE A HG22 1 
ATOM   1632 H  HG23 . ILE A 1 105 ? 38.54600  -30.29600 34.23100 1.000 59.09000  ? 105 ILE A HG23 1 
ATOM   1633 H  HD11 . ILE A 1 105 ? 34.80300  -28.82700 34.67400 1.000 51.66000  ? 105 ILE A HD11 1 
ATOM   1634 H  HD12 . ILE A 1 105 ? 34.82900  -30.04600 33.65600 1.000 51.66000  ? 105 ILE A HD12 1 
ATOM   1635 H  HD13 . ILE A 1 105 ? 35.75400  -30.07000 34.94700 1.000 51.66000  ? 105 ILE A HD13 1 
ATOM   1636 N  N    . LYS A 1 106 ? 40.08900  -30.38100 30.73800 1.000 53.19585  ? 106 LYS A N    1 
ATOM   1637 C  CA   . LYS A 1 106 ? 40.58200  -31.41800 29.84200 1.000 55.00923  ? 106 LYS A CA   1 
ATOM   1638 C  C    . LYS A 1 106 ? 39.79500  -32.70200 30.07600 1.000 58.62019  ? 106 LYS A C    1 
ATOM   1639 O  O    . LYS A 1 106 ? 39.43200  -33.02600 31.21000 1.000 58.25172  ? 106 LYS A O    1 
ATOM   1640 C  CB   . LYS A 1 106 ? 42.07600  -31.64900 30.07200 1.000 57.20949  ? 106 LYS A CB   1 
ATOM   1641 C  CG   . LYS A 1 106 ? 42.75200  -32.51700 29.02100 1.000 62.47854  ? 106 LYS A CG   1 
ATOM   1642 C  CD   . LYS A 1 106 ? 44.00700  -33.19600 29.56400 1.000 73.03770  ? 106 LYS A CD   1 
ATOM   1643 C  CE   . LYS A 1 106 ? 45.27400  -32.56800 28.99500 1.000 86.73672  ? 106 LYS A CE   1 
ATOM   1644 N  NZ   . LYS A 1 106 ? 46.50900  -33.10500 29.63600 1.000 84.57330  ? 106 LYS A NZ   1 
ATOM   1645 H  H    . LYS A 1 106 ? 40.67400  -30.07700 31.29100 1.000 63.95000  ? 106 LYS A H    1 
ATOM   1646 H  HA   . LYS A 1 106 ? 40.46800  -31.14700 28.91700 1.000 66.12000  ? 106 LYS A HA   1 
ATOM   1647 H  HB2  . LYS A 1 106 ? 42.52500  -30.78900 30.07300 1.000 68.77000  ? 106 LYS A HB2  1 
ATOM   1648 H  HB3  . LYS A 1 106 ? 42.19300  -32.08500 30.93100 1.000 68.77000  ? 106 LYS A HB3  1 
ATOM   1649 H  HG2  . LYS A 1 106 ? 42.13500  -33.20800 28.73200 1.000 75.09000  ? 106 LYS A HG2  1 
ATOM   1650 H  HG3  . LYS A 1 106 ? 43.00800  -31.96500 28.26700 1.000 75.09000  ? 106 LYS A HG3  1 
ATOM   1651 H  HD2  . LYS A 1 106 ? 44.02900  -33.10600 30.52900 1.000 87.76000  ? 106 LYS A HD2  1 
ATOM   1652 H  HD3  . LYS A 1 106 ? 43.99600  -34.13500 29.31900 1.000 87.76000  ? 106 LYS A HD3  1 
ATOM   1653 H  HE2  . LYS A 1 106 ? 45.32200  -32.75400 28.04400 1.000 104.20000 ? 106 LYS A HE2  1 
ATOM   1654 H  HE3  . LYS A 1 106 ? 45.24800  -31.61000 29.14500 1.000 104.20000 ? 106 LYS A HE3  1 
ATOM   1655 H  HZ1  . LYS A 1 106 ? 47.22800  -32.71200 29.28800 1.000 101.60000 ? 106 LYS A HZ1  1 
ATOM   1656 H  HZ2  . LYS A 1 106 ? 46.49000  -32.94900 30.51200 1.000 101.60000 ? 106 LYS A HZ2  1 
ATOM   1657 H  HZ3  . LYS A 1 106 ? 46.56600  -33.98300 29.50000 1.000 101.60000 ? 106 LYS A HZ3  1 
ATOM   1658 N  N    . TRP A 1 107 ? 39.52300  -33.43200 28.99300 1.000 57.80956  ? 107 TRP A N    1 
ATOM   1659 C  CA   . TRP A 1 107 ? 38.66800  -34.60800 29.08400 1.000 63.64974  ? 107 TRP A CA   1 
ATOM   1660 C  C    . TRP A 1 107 ? 39.18800  -35.57900 30.13500 1.000 63.13125  ? 107 TRP A C    1 
ATOM   1661 O  O    . TRP A 1 107 ? 40.39700  -35.73500 30.32800 1.000 62.04428  ? 107 TRP A O    1 
ATOM   1662 C  CB   . TRP A 1 107 ? 38.57500  -35.32900 27.73500 1.000 67.06067  ? 107 TRP A CB   1 
ATOM   1663 C  CG   . TRP A 1 107 ? 38.28100  -36.81100 27.87200 1.000 69.45043  ? 107 TRP A CG   1 
ATOM   1664 C  CD1  . TRP A 1 107 ? 39.18800  -37.81500 28.07200 1.000 73.31142  ? 107 TRP A CD1  1 
ATOM   1665 C  CD2  . TRP A 1 107 ? 36.99200  -37.44300 27.83100 1.000 72.90085  ? 107 TRP A CD2  1 
ATOM   1666 N  NE1  . TRP A 1 107 ? 38.54500  -39.02600 28.15800 1.000 76.14071  ? 107 TRP A NE1  1 
ATOM   1667 C  CE2  . TRP A 1 107 ? 37.19800  -38.82600 28.01000 1.000 75.01426  ? 107 TRP A CE2  1 
ATOM   1668 C  CE3  . TRP A 1 107 ? 35.68600  -36.97400 27.65900 1.000 76.04859  ? 107 TRP A CE3  1 
ATOM   1669 C  CZ2  . TRP A 1 107 ? 36.14800  -39.74300 28.01800 1.000 78.39098  ? 107 TRP A CZ2  1 
ATOM   1670 C  CZ3  . TRP A 1 107 ? 34.64300  -37.88900 27.66700 1.000 74.38787  ? 107 TRP A CZ3  1 
ATOM   1671 C  CH2  . TRP A 1 107 ? 34.88100  -39.25600 27.84400 1.000 68.12396  ? 107 TRP A CH2  1 
ATOM   1672 H  H    . TRP A 1 107 ? 39.82000  -33.26700 28.20300 1.000 69.48000  ? 107 TRP A H    1 
ATOM   1673 H  HA   . TRP A 1 107 ? 37.77800  -34.31600 29.33700 1.000 76.50000  ? 107 TRP A HA   1 
ATOM   1674 H  HB2  . TRP A 1 107 ? 37.86200  -34.93000 27.21300 1.000 80.58000  ? 107 TRP A HB2  1 
ATOM   1675 H  HB3  . TRP A 1 107 ? 39.42100  -35.23500 27.26900 1.000 80.58000  ? 107 TRP A HB3  1 
ATOM   1676 H  HD1  . TRP A 1 107 ? 40.10800  -37.69500 28.14000 1.000 88.09000  ? 107 TRP A HD1  1 
ATOM   1677 H  HE1  . TRP A 1 107 ? 38.92600  -39.78600 28.28500 1.000 91.48000  ? 107 TRP A HE1  1 
ATOM   1678 H  HE3  . TRP A 1 107 ? 35.51900  -36.06600 27.54200 1.000 91.37000  ? 107 TRP A HE3  1 
ATOM   1679 H  HZ2  . TRP A 1 107 ? 36.30200  -40.65300 28.13700 1.000 94.18000  ? 107 TRP A HZ2  1 
ATOM   1680 H  HZ3  . TRP A 1 107 ? 33.77000  -37.58900 27.55300 1.000 89.38000  ? 107 TRP A HZ3  1 
ATOM   1681 H  HH2  . TRP A 1 107 ? 34.16300  -39.84700 27.84400 1.000 81.86000  ? 107 TRP A HH2  1 
ATOM   1682 N  N    . ALA A 1 108 ? 38.25000  -36.24500 30.80700 1.000 64.82093  ? 108 ALA A N    1 
ATOM   1683 C  CA   . ALA A 1 108 ? 38.56200  -37.34900 31.70300 1.000 61.35209  ? 108 ALA A CA   1 
ATOM   1684 C  C    . ALA A 1 108 ? 37.27200  -37.94000 32.25600 1.000 65.20782  ? 108 ALA A C    1 
ATOM   1685 O  O    . ALA A 1 108 ? 36.31200  -37.20500 32.50900 1.000 69.63466  ? 108 ALA A O    1 
ATOM   1686 C  CB   . ALA A 1 108 ? 39.46900  -36.88700 32.84300 1.000 62.69173  ? 108 ALA A CB   1 
ATOM   1687 H  H    . ALA A 1 108 ? 37.40900  -36.07100 30.75700 1.000 77.90000  ? 108 ALA A H    1 
ATOM   1688 H  HA   . ALA A 1 108 ? 39.04000  -38.03700 31.21400 1.000 73.74000  ? 108 ALA A HA   1 
ATOM   1689 H  HB1  . ALA A 1 108 ? 39.59200  -37.62000 33.46600 1.000 75.34000  ? 108 ALA A HB1  1 
ATOM   1690 H  HB2  . ALA A 1 108 ? 40.32600  -36.61800 32.47600 1.000 75.34000  ? 108 ALA A HB2  1 
ATOM   1691 H  HB3  . ALA A 1 108 ? 39.05200  -36.13600 33.29400 1.000 75.34000  ? 108 ALA A HB3  1 
ATOM   1692 N  N    . ASP A 1 109 ? 37.23800  -39.25900 32.42500 1.000 64.83409  ? 109 ASP A N    1 
ATOM   1693 C  CA   . ASP A 1 109 ? 36.17400  -39.94900 33.15600 1.000 72.92453  ? 109 ASP A CA   1 
ATOM   1694 C  C    . ASP A 1 109 ? 34.79500  -39.35800 32.86300 1.000 64.77882  ? 109 ASP A C    1 
ATOM   1695 O  O    . ASP A 1 109 ? 34.04300  -38.98600 33.76600 1.000 59.65189  ? 109 ASP A O    1 
ATOM   1696 C  CB   . ASP A 1 109 ? 36.44800  -39.92200 34.66200 1.000 71.56121  ? 109 ASP A CB   1 
ATOM   1697 C  CG   . ASP A 1 109 ? 37.91800  -40.09100 34.99700 1.000 79.94380  ? 109 ASP A CG   1 
ATOM   1698 O  OD1  . ASP A 1 109 ? 38.49500  -41.13800 34.63600 1.000 88.41323  ? 109 ASP A OD1  1 
ATOM   1699 O  OD2  . ASP A 1 109 ? 38.49300  -39.17900 35.63100 1.000 77.89618  ? 109 ASP A OD2  1 
ATOM   1700 H  H    . ASP A 1 109 ? 37.83600  -39.79400 32.11600 1.000 77.91000  ? 109 ASP A H    1 
ATOM   1701 H  HA   . ASP A 1 109 ? 36.16500  -40.86900 32.84900 1.000 87.63000  ? 109 ASP A HA   1 
ATOM   1702 H  HB2  . ASP A 1 109 ? 36.15500  -39.07000 35.02200 1.000 85.98000  ? 109 ASP A HB2  1 
ATOM   1703 H  HB3  . ASP A 1 109 ? 35.96000  -40.64600 35.08500 1.000 85.98000  ? 109 ASP A HB3  1 
ATOM   1704 N  N    . ASN A 1 110 ? 34.46000  -39.27400 31.57800 1.000 65.89211  ? 110 ASN A N    1 
ATOM   1705 C  CA   . ASN A 1 110 ? 33.13400  -38.82300 31.15500 1.000 62.14956  ? 110 ASN A CA   1 
ATOM   1706 C  C    . ASN A 1 110 ? 32.76100  -37.48900 31.79900 1.000 52.90898  ? 110 ASN A C    1 
ATOM   1707 O  O    . ASN A 1 110 ? 31.62000  -37.27700 32.21400 1.000 52.32469  ? 110 ASN A O    1 
ATOM   1708 C  CB   . ASN A 1 110 ? 32.07000  -39.87500 31.48100 1.000 64.91041  ? 110 ASN A CB   1 
ATOM   1709 C  CG   . ASN A 1 110 ? 32.44400  -41.25900 30.99600 1.000 76.77236  ? 110 ASN A CG   1 
ATOM   1710 O  OD1  . ASN A 1 110 ? 33.56100  -41.48900 30.53000 1.000 84.58119  ? 110 ASN A OD1  1 
ATOM   1711 N  ND2  . ASN A 1 110 ? 31.50900  -42.19600 31.11100 1.000 72.69293  ? 110 ASN A ND2  1 
ATOM   1712 H  H    . ASN A 1 110 ? 34.98600  -39.47300 30.92700 1.000 79.18000  ? 110 ASN A H    1 
ATOM   1713 H  HA   . ASN A 1 110 ? 33.16100  -38.69100 30.19400 1.000 74.69000  ? 110 ASN A HA   1 
ATOM   1714 H  HB2  . ASN A 1 110 ? 31.95100  -39.91700 32.44300 1.000 78.01000  ? 110 ASN A HB2  1 
ATOM   1715 H  HB3  . ASN A 1 110 ? 31.23600  -39.62400 31.05400 1.000 78.01000  ? 110 ASN A HB3  1 
ATOM   1716 H  HD21 . ASN A 1 110 ? 30.74200  -41.99900 31.44700 1.000 87.35000  ? 110 ASN A HD21 1 
ATOM   1717 H  HD22 . ASN A 1 110 ? 31.67100  -42.99900 30.85100 1.000 87.35000  ? 110 ASN A HD22 1 
ATOM   1718 N  N    . ASN A 1 111 ? 33.72600  -36.57700 31.88300 1.000 51.99834  ? 111 ASN A N    1 
ATOM   1719 C  CA   . ASN A 1 111 ? 33.50500  -35.28500 32.52000 1.000 48.25842  ? 111 ASN A CA   1 
ATOM   1720 C  C    . ASN A 1 111 ? 33.05600  -34.20400 31.54300 1.000 48.86112  ? 111 ASN A C    1 
ATOM   1721 O  O    . ASN A 1 111 ? 33.03700  -33.02400 31.91200 1.000 47.47675  ? 111 ASN A O    1 
ATOM   1722 C  CB   . ASN A 1 111 ? 34.77600  -34.82800 33.24500 1.000 49.42172  ? 111 ASN A CB   1 
ATOM   1723 C  CG   . ASN A 1 111 ? 35.89000  -34.43000 32.29200 1.000 53.56169  ? 111 ASN A CG   1 
ATOM   1724 O  OD1  . ASN A 1 111 ? 35.76600  -34.56100 31.07300 1.000 56.83050  ? 111 ASN A OD1  1 
ATOM   1725 N  ND2  . ASN A 1 111 ? 36.99200  -33.94400 32.85000 1.000 54.10912  ? 111 ASN A ND2  1 
ATOM   1726 H  H    . ASN A 1 111 ? 34.52200  -36.68500 31.57500 1.000 62.51000  ? 111 ASN A H    1 
ATOM   1727 H  HA   . ASN A 1 111 ? 32.80300  -35.39300 33.18200 1.000 58.02000  ? 111 ASN A HA   1 
ATOM   1728 H  HB2  . ASN A 1 111 ? 34.56500  -34.05900 33.79700 1.000 59.42000  ? 111 ASN A HB2  1 
ATOM   1729 H  HB3  . ASN A 1 111 ? 35.10200  -35.55500 33.79900 1.000 59.42000  ? 111 ASN A HB3  1 
ATOM   1730 H  HD21 . ASN A 1 111 ? 37.65300  -33.70200 32.35600 1.000 65.04000  ? 111 ASN A HD21 1 
ATOM   1731 H  HD22 . ASN A 1 111 ? 37.04400  -33.87000 33.70500 1.000 65.04000  ? 111 ASN A HD22 1 
ATOM   1732 N  N    . SER A 1 112 ? 32.68600  -34.57400 30.31500 1.000 44.71326  ? 112 SER A N    1 
ATOM   1733 C  CA   . SER A 1 112 ? 32.35100  -33.56500 29.31300 1.000 46.80824  ? 112 SER A CA   1 
ATOM   1734 C  C    . SER A 1 112 ? 31.19200  -32.68600 29.77200 1.000 46.34766  ? 112 SER A C    1 
ATOM   1735 O  O    . SER A 1 112 ? 31.19900  -31.47100 29.54600 1.000 46.99248  ? 112 SER A O    1 
ATOM   1736 C  CB   . SER A 1 112 ? 32.02100  -34.23700 27.98000 1.000 49.20327  ? 112 SER A CB   1 
ATOM   1737 O  OG   . SER A 1 112 ? 30.74000  -34.83900 28.00900 1.000 54.11438  ? 112 SER A OG   1 
ATOM   1738 H  H    . SER A 1 112 ? 32.62300  -35.38700 30.04200 1.000 53.77000  ? 112 SER A H    1 
ATOM   1739 H  HA   . SER A 1 112 ? 33.12300  -32.99300 29.18000 1.000 56.28000  ? 112 SER A HA   1 
ATOM   1740 H  HB2  . SER A 1 112 ? 32.03700  -33.56700 27.27900 1.000 59.16000  ? 112 SER A HB2  1 
ATOM   1741 H  HB3  . SER A 1 112 ? 32.68500  -34.92100 27.80100 1.000 59.16000  ? 112 SER A HB3  1 
ATOM   1742 H  HG   . SER A 1 112 ? 30.71200  -35.42700 28.60700 1.000 65.05000  ? 112 SER A HG   1 
ATOM   1743 N  N    . TYR A 1 113 ? 30.18900  -33.27700 30.42800 1.000 47.94522  ? 113 TYR A N    1 
ATOM   1744 C  CA   . TYR A 1 113 ? 29.05400  -32.48200 30.88800 1.000 46.45820  ? 113 TYR A CA   1 
ATOM   1745 C  C    . TYR A 1 113 ? 29.48000  -31.43700 31.91000 1.000 44.91328  ? 113 TYR A C    1 
ATOM   1746 O  O    . TYR A 1 113 ? 28.92600  -30.33100 31.93200 1.000 40.89438  ? 113 TYR A O    1 
ATOM   1747 C  CB   . TYR A 1 113 ? 27.96900  -33.39500 31.46300 1.000 49.03219  ? 113 TYR A CB   1 
ATOM   1748 C  CG   . TYR A 1 113 ? 28.26000  -33.97600 32.83100 1.000 48.17683  ? 113 TYR A CG   1 
ATOM   1749 C  CD1  . TYR A 1 113 ? 28.96400  -35.16400 32.96500 1.000 47.32936  ? 113 TYR A CD1  1 
ATOM   1750 C  CD2  . TYR A 1 113 ? 27.81400  -33.34600 33.98700 1.000 46.58190  ? 113 TYR A CD2  1 
ATOM   1751 C  CE1  . TYR A 1 113 ? 29.22400  -35.70500 34.20800 1.000 46.45294  ? 113 TYR A CE1  1 
ATOM   1752 C  CE2  . TYR A 1 113 ? 28.06500  -33.88400 35.23900 1.000 47.67940  ? 113 TYR A CE2  1 
ATOM   1753 C  CZ   . TYR A 1 113 ? 28.77300  -35.06100 35.34300 1.000 48.56109  ? 113 TYR A CZ   1 
ATOM   1754 O  OH   . TYR A 1 113 ? 29.03200  -35.59800 36.58500 1.000 47.58728  ? 113 TYR A OH   1 
ATOM   1755 H  H    . TYR A 1 113 ? 30.14500  -34.11500 30.61400 1.000 57.65000  ? 113 TYR A H    1 
ATOM   1756 H  HA   . TYR A 1 113 ? 28.67200  -32.01400 30.12900 1.000 55.86000  ? 113 TYR A HA   1 
ATOM   1757 H  HB2  . TYR A 1 113 ? 27.14800  -32.88400 31.53600 1.000 58.95000  ? 113 TYR A HB2  1 
ATOM   1758 H  HB3  . TYR A 1 113 ? 27.84300  -34.14000 30.85500 1.000 58.95000  ? 113 TYR A HB3  1 
ATOM   1759 H  HD1  . TYR A 1 113 ? 29.26700  -35.60400 32.20300 1.000 56.01000  ? 113 TYR A HD1  1 
ATOM   1760 H  HD2  . TYR A 1 113 ? 27.33900  -32.55000 33.91800 1.000 56.91000  ? 113 TYR A HD2  1 
ATOM   1761 H  HE1  . TYR A 1 113 ? 29.70200  -36.50000 34.28000 1.000 57.33000  ? 113 TYR A HE1  1 
ATOM   1762 H  HE2  . TYR A 1 113 ? 27.75800  -33.45400 36.00400 1.000 55.85000  ? 113 TYR A HE2  1 
ATOM   1763 H  HH   . TYR A 1 113 ? 29.49500  -36.29500 36.50600 1.000 57.22000  ? 113 TYR A HH   1 
ATOM   1764 N  N    . LEU A 1 114 ? 30.46700  -31.75600 32.75200 1.000 46.45820  ? 114 LEU A N    1 
ATOM   1765 C  CA   . LEU A 1 114 ? 30.95000  -30.78000 33.72300 1.000 44.92118  ? 114 LEU A CA   1 
ATOM   1766 C  C    . LEU A 1 114 ? 31.67200  -29.63100 33.03400 1.000 45.77391  ? 114 LEU A C    1 
ATOM   1767 O  O    . LEU A 1 114 ? 31.56200  -28.47400 33.45900 1.000 42.21822  ? 114 LEU A O    1 
ATOM   1768 C  CB   . LEU A 1 114 ? 31.87800  -31.45500 34.73100 1.000 43.48942  ? 114 LEU A CB   1 
ATOM   1769 C  CG   . LEU A 1 114 ? 31.22400  -32.46000 35.67800 1.000 48.42423  ? 114 LEU A CG   1 
ATOM   1770 C  CD1  . LEU A 1 114 ? 32.28500  -33.32000 36.34100 1.000 46.08447  ? 114 LEU A CD1  1 
ATOM   1771 C  CD2  . LEU A 1 114 ? 30.37000  -31.75100 36.72100 1.000 46.86615  ? 114 LEU A CD2  1 
ATOM   1772 H  H    . LEU A 1 114 ? 30.86500  -32.51800 32.77900 1.000 55.87000  ? 114 LEU A H    1 
ATOM   1773 H  HA   . LEU A 1 114 ? 30.19000  -30.42000 34.20500 1.000 54.02000  ? 114 LEU A HA   1 
ATOM   1774 H  HB2  . LEU A 1 114 ? 32.56400  -31.93100 34.23800 1.000 52.30000  ? 114 LEU A HB2  1 
ATOM   1775 H  HB3  . LEU A 1 114 ? 32.28200  -30.76500 35.27900 1.000 52.30000  ? 114 LEU A HB3  1 
ATOM   1776 H  HG   . LEU A 1 114 ? 30.63600  -33.03900 35.16800 1.000 58.22000  ? 114 LEU A HG   1 
ATOM   1777 H  HD11 . LEU A 1 114 ? 31.85400  -33.93600 36.95500 1.000 55.42000  ? 114 LEU A HD11 1 
ATOM   1778 H  HD12 . LEU A 1 114 ? 32.76300  -33.81500 35.65700 1.000 55.42000  ? 114 LEU A HD12 1 
ATOM   1779 H  HD13 . LEU A 1 114 ? 32.89900  -32.74600 36.82500 1.000 55.42000  ? 114 LEU A HD13 1 
ATOM   1780 H  HD21 . LEU A 1 114 ? 30.00100  -32.41100 37.32900 1.000 56.35000  ? 114 LEU A HD21 1 
ATOM   1781 H  HD22 . LEU A 1 114 ? 30.92600  -31.12500 37.21100 1.000 56.35000  ? 114 LEU A HD22 1 
ATOM   1782 H  HD23 . LEU A 1 114 ? 29.65300  -31.27600 36.27300 1.000 56.35000  ? 114 LEU A HD23 1 
ATOM   1783 N  N    . ALA A 1 115 ? 32.42200  -29.93100 31.97200 1.000 43.40257  ? 115 ALA A N    1 
ATOM   1784 C  CA   . ALA A 1 115 ? 33.12500  -28.88400 31.24000 1.000 42.36034  ? 115 ALA A CA   1 
ATOM   1785 C  C    . ALA A 1 115 ? 32.14700  -27.86500 30.67000 1.000 42.65511  ? 115 ALA A C    1 
ATOM   1786 O  O    . ALA A 1 115 ? 32.29900  -26.65500 30.87800 1.000 43.43679  ? 115 ALA A O    1 
ATOM   1787 C  CB   . ALA A 1 115 ? 33.96500  -29.50300 30.12300 1.000 47.56886  ? 115 ALA A CB   1 
ATOM   1788 H  H    . ALA A 1 115 ? 32.53900  -30.72400 31.66100 1.000 52.20000  ? 115 ALA A H    1 
ATOM   1789 H  HA   . ALA A 1 115 ? 33.72200  -28.42300 31.84900 1.000 50.95000  ? 115 ALA A HA   1 
ATOM   1790 H  HB1  . ALA A 1 115 ? 34.42700  -28.79500 29.64600 1.000 57.20000  ? 115 ALA A HB1  1 
ATOM   1791 H  HB2  . ALA A 1 115 ? 34.61000  -30.11300 30.51400 1.000 57.20000  ? 115 ALA A HB2  1 
ATOM   1792 H  HB3  . ALA A 1 115 ? 33.38000  -29.98300 29.51600 1.000 57.20000  ? 115 ALA A HB3  1 
ATOM   1793 N  N    . THR A 1 116 ? 31.13300  -28.33500 29.94000 1.000 39.81793  ? 116 THR A N    1 
ATOM   1794 C  CA   . THR A 1 116 ? 30.18100  -27.40500 29.34200 1.000 46.19238  ? 116 THR A CA   1 
ATOM   1795 C  C    . THR A 1 116 ? 29.31300  -26.73700 30.40500 1.000 45.96341  ? 116 THR A C    1 
ATOM   1796 O  O    . THR A 1 116 ? 28.89300  -25.58700 30.22800 1.000 46.39240  ? 116 THR A O    1 
ATOM   1797 C  CB   . THR A 1 116 ? 29.32000  -28.12400 28.29600 1.000 45.29754  ? 116 THR A CB   1 
ATOM   1798 O  OG1  . THR A 1 116 ? 28.29300  -27.24100 27.82600 1.000 52.82739  ? 116 THR A OG1  1 
ATOM   1799 C  CG2  . THR A 1 116 ? 28.67700  -29.38500 28.86200 1.000 44.36585  ? 116 THR A CG2  1 
ATOM   1800 H  H    . THR A 1 116 ? 30.97900  -29.16600 29.78200 1.000 47.89000  ? 116 THR A H    1 
ATOM   1801 H  HA   . THR A 1 116 ? 30.66800  -26.70600 28.88000 1.000 55.55000  ? 116 THR A HA   1 
ATOM   1802 H  HB   . THR A 1 116 ? 29.89000  -28.39000 27.55800 1.000 54.47000  ? 116 THR A HB   1 
ATOM   1803 H  HG1  . THR A 1 116 ? 27.81600  -27.63300 27.25600 1.000 63.51000  ? 116 THR A HG1  1 
ATOM   1804 H  HG21 . THR A 1 116 ? 28.13100  -29.81200 28.18400 1.000 53.35000  ? 116 THR A HG21 1 
ATOM   1805 H  HG22 . THR A 1 116 ? 29.36400  -30.00600 29.15000 1.000 53.35000  ? 116 THR A HG22 1 
ATOM   1806 H  HG23 . THR A 1 116 ? 28.11800  -29.15900 29.62200 1.000 53.35000  ? 116 THR A HG23 1 
ATOM   1807 N  N    . ALA A 1 117 ? 29.04500  -27.42700 31.51600 1.000 46.26344  ? 117 ALA A N    1 
ATOM   1808 C  CA   . ALA A 1 117 ? 28.36600  -26.78200 32.63600 1.000 43.85789  ? 117 ALA A CA   1 
ATOM   1809 C  C    . ALA A 1 117 ? 29.21300  -25.64900 33.20300 1.000 42.73144  ? 117 ALA A C    1 
ATOM   1810 O  O    . ALA A 1 117 ? 28.71600  -24.54100 33.43900 1.000 44.74484  ? 117 ALA A O    1 
ATOM   1811 C  CB   . ALA A 1 117 ? 28.05200  -27.81100 33.72200 1.000 47.59518  ? 117 ALA A CB   1 
ATOM   1812 H  H    . ALA A 1 117 ? 29.24200  -28.25400 31.64200 1.000 55.63000  ? 117 ALA A H    1 
ATOM   1813 H  HA   . ALA A 1 117 ? 27.52700  -26.41000 32.32200 1.000 52.74000  ? 117 ALA A HA   1 
ATOM   1814 H  HB1  . ALA A 1 117 ? 27.59800  -27.36800 34.45500 1.000 57.23000  ? 117 ALA A HB1  1 
ATOM   1815 H  HB2  . ALA A 1 117 ? 27.48100  -28.50000 33.34800 1.000 57.23000  ? 117 ALA A HB2  1 
ATOM   1816 H  HB3  . ALA A 1 117 ? 28.88200  -28.20300 34.03500 1.000 57.23000  ? 117 ALA A HB3  1 
ATOM   1817 N  N    . LEU A 1 118 ? 30.50400  -25.90800 33.42100 1.000 42.85251  ? 118 LEU A N    1 
ATOM   1818 C  CA   . LEU A 1 118 ? 31.38400  -24.88300 33.97200 1.000 45.11067  ? 118 LEU A CA   1 
ATOM   1819 C  C    . LEU A 1 118 ? 31.55800  -23.72200 33.00100 1.000 44.12108  ? 118 LEU A C    1 
ATOM   1820 O  O    . LEU A 1 118 ? 31.56400  -22.55600 33.41300 1.000 44.51060  ? 118 LEU A O    1 
ATOM   1821 C  CB   . LEU A 1 118 ? 32.73900  -25.49600 34.32300 1.000 45.29754  ? 118 LEU A CB   1 
ATOM   1822 C  CG   . LEU A 1 118 ? 33.88000  -24.51900 34.61600 1.000 48.46897  ? 118 LEU A CG   1 
ATOM   1823 C  CD1  . LEU A 1 118 ? 33.51400  -23.59200 35.76000 1.000 50.79293  ? 118 LEU A CD1  1 
ATOM   1824 C  CD2  . LEU A 1 118 ? 35.16100  -25.27900 34.92600 1.000 50.29287  ? 118 LEU A CD2  1 
ATOM   1825 H  H    . LEU A 1 118 ? 30.88900  -26.66100 33.26000 1.000 51.53000  ? 118 LEU A H    1 
ATOM   1826 H  HA   . LEU A 1 118 ? 30.98800  -24.53400 34.78600 1.000 54.25000  ? 118 LEU A HA   1 
ATOM   1827 H  HB2  . LEU A 1 118 ? 32.62400  -26.04400 35.11500 1.000 54.47000  ? 118 LEU A HB2  1 
ATOM   1828 H  HB3  . LEU A 1 118 ? 33.02200  -26.04700 33.57700 1.000 54.47000  ? 118 LEU A HB3  1 
ATOM   1829 H  HG   . LEU A 1 118 ? 34.03600  -23.97100 33.83100 1.000 58.28000  ? 118 LEU A HG   1 
ATOM   1830 H  HD11 . LEU A 1 118 ? 34.27200  -23.02000 35.95900 1.000 61.07000  ? 118 LEU A HD11 1 
ATOM   1831 H  HD12 . LEU A 1 118 ? 32.75200  -23.05100 35.49800 1.000 61.07000  ? 118 LEU A HD12 1 
ATOM   1832 H  HD13 . LEU A 1 118 ? 33.28800  -24.12500 36.53900 1.000 61.07000  ? 118 LEU A HD13 1 
ATOM   1833 H  HD21 . LEU A 1 118 ? 35.86900  -24.64300 35.11300 1.000 60.47000  ? 118 LEU A HD21 1 
ATOM   1834 H  HD22 . LEU A 1 118 ? 35.01300  -25.84500 35.70000 1.000 60.47000  ? 118 LEU A HD22 1 
ATOM   1835 H  HD23 . LEU A 1 118 ? 35.39900  -25.82400 34.16000 1.000 60.47000  ? 118 LEU A HD23 1 
ATOM   1836 N  N    . LEU A 1 119 ? 31.71500  -24.01800 31.70900 1.000 44.17109  ? 119 LEU A N    1 
ATOM   1837 C  CA   . LEU A 1 119 ? 31.88000  -22.95000 30.72800 1.000 45.68179  ? 119 LEU A CA   1 
ATOM   1838 C  C    . LEU A 1 119 ? 30.62100  -22.10000 30.63100 1.000 43.06832  ? 119 LEU A C    1 
ATOM   1839 O  O    . LEU A 1 119 ? 30.69900  -20.87900 30.46000 1.000 45.98709  ? 119 LEU A O    1 
ATOM   1840 C  CB   . LEU A 1 119 ? 32.23400  -23.53900 29.36400 1.000 47.77415  ? 119 LEU A CB   1 
ATOM   1841 C  CG   . LEU A 1 119 ? 33.60600  -24.20500 29.25100 1.000 47.47411  ? 119 LEU A CG   1 
ATOM   1842 C  CD1  . LEU A 1 119 ? 33.60800  -25.22100 28.12000 1.000 48.44002  ? 119 LEU A CD1  1 
ATOM   1843 C  CD2  . LEU A 1 119 ? 34.69800  -23.16800 29.03600 1.000 50.84294  ? 119 LEU A CD2  1 
ATOM   1844 H  H    . LEU A 1 119 ? 31.73000  -24.81300 31.38200 1.000 53.12000  ? 119 LEU A H    1 
ATOM   1845 H  HA   . LEU A 1 119 ? 32.61300  -22.37800 31.00700 1.000 54.93000  ? 119 LEU A HA   1 
ATOM   1846 H  HB2  . LEU A 1 119 ? 31.57000  -24.21200 29.14500 1.000 57.45000  ? 119 LEU A HB2  1 
ATOM   1847 H  HB3  . LEU A 1 119 ? 32.20800  -22.82300 28.71000 1.000 57.45000  ? 119 LEU A HB3  1 
ATOM   1848 H  HG   . LEU A 1 119 ? 33.79800  -24.66900 30.08000 1.000 57.08000  ? 119 LEU A HG   1 
ATOM   1849 H  HD11 . LEU A 1 119 ? 34.49000  -25.62000 28.05500 1.000 58.24000  ? 119 LEU A HD11 1 
ATOM   1850 H  HD12 . LEU A 1 119 ? 32.94800  -25.90600 28.31000 1.000 58.24000  ? 119 LEU A HD12 1 
ATOM   1851 H  HD13 . LEU A 1 119 ? 33.38600  -24.77000 27.29000 1.000 58.24000  ? 119 LEU A HD13 1 
ATOM   1852 H  HD21 . LEU A 1 119 ? 35.55300  -23.62000 28.95900 1.000 61.12000  ? 119 LEU A HD21 1 
ATOM   1853 H  HD22 . LEU A 1 119 ? 34.51000  -22.67500 28.22200 1.000 61.12000  ? 119 LEU A HD22 1 
ATOM   1854 H  HD23 . LEU A 1 119 ? 34.71200  -22.56200 29.79400 1.000 61.12000  ? 119 LEU A HD23 1 
ATOM   1855 N  N    . THR A 1 120 ? 29.45000  -22.73100 30.73600 1.000 44.80800  ? 120 THR A N    1 
ATOM   1856 C  CA   . THR A 1 120 ? 28.20000  -21.98100 30.69400 1.000 42.86303  ? 120 THR A CA   1 
ATOM   1857 C  C    . THR A 1 120 ? 28.09500  -21.02200 31.87300 1.000 46.76613  ? 120 THR A C    1 
ATOM   1858 O  O    . THR A 1 120 ? 27.67200  -19.87200 31.71000 1.000 48.50845  ? 120 THR A O    1 
ATOM   1859 C  CB   . THR A 1 120 ? 27.01300  -22.94500 30.68500 1.000 48.15577  ? 120 THR A CB   1 
ATOM   1860 O  OG1  . THR A 1 120 ? 27.07000  -23.77100 29.51500 1.000 47.58465  ? 120 THR A OG1  1 
ATOM   1861 C  CG2  . THR A 1 120 ? 25.70400  -22.17700 30.69700 1.000 46.72666  ? 120 THR A CG2  1 
ATOM   1862 H  H    . THR A 1 120 ? 29.35500  -23.58100 30.83000 1.000 53.88000  ? 120 THR A H    1 
ATOM   1863 H  HA   . THR A 1 120 ? 28.17500  -21.46000 29.87600 1.000 51.55000  ? 120 THR A HA   1 
ATOM   1864 H  HB   . THR A 1 120 ? 27.04600  -23.50500 31.47600 1.000 57.90000  ? 120 THR A HB   1 
ATOM   1865 H  HG1  . THR A 1 120 ? 27.77900  -24.22100 29.51600 1.000 57.21000  ? 120 THR A HG1  1 
ATOM   1866 H  HG21 . THR A 1 120 ? 24.97400  -22.76300 30.44400 1.000 56.18000  ? 120 THR A HG21 1 
ATOM   1867 H  HG22 . THR A 1 120 ? 25.53300  -21.82600 31.58500 1.000 56.18000  ? 120 THR A HG22 1 
ATOM   1868 H  HG23 . THR A 1 120 ? 25.74700  -21.43800 30.07000 1.000 56.18000  ? 120 THR A HG23 1 
ATOM   1869 N  N    . LEU A 1 121 ? 28.47300  -21.47900 33.07000 1.000 46.75297  ? 121 LEU A N    1 
ATOM   1870 C  CA   . LEU A 1 121 ? 28.39200  -20.62400 34.25000 1.000 44.79221  ? 121 LEU A CA   1 
ATOM   1871 C  C    . LEU A 1 121 ? 29.14700  -19.31900 34.04300 1.000 48.52687  ? 121 LEU A C    1 
ATOM   1872 O  O    . LEU A 1 121 ? 28.67900  -18.24900 34.44700 1.000 50.05337  ? 121 LEU A O    1 
ATOM   1873 C  CB   . LEU A 1 121 ? 28.94500  -21.36000 35.47100 1.000 47.20303  ? 121 LEU A CB   1 
ATOM   1874 C  CG   . LEU A 1 121 ? 28.08600  -22.48100 36.05400 1.000 46.39767  ? 121 LEU A CG   1 
ATOM   1875 C  CD1  . LEU A 1 121 ? 28.83100  -23.17300 37.18800 1.000 51.87201  ? 121 LEU A CD1  1 
ATOM   1876 C  CD2  . LEU A 1 121 ? 26.74500  -21.94700 36.53700 1.000 48.85586  ? 121 LEU A CD2  1 
ATOM   1877 H  H    . LEU A 1 121 ? 28.77700  -22.26900 33.22200 1.000 56.22000  ? 121 LEU A H    1 
ATOM   1878 H  HA   . LEU A 1 121 ? 27.45900  -20.41500 34.41600 1.000 53.86000  ? 121 LEU A HA   1 
ATOM   1879 H  HB2  . LEU A 1 121 ? 29.79400  -21.75500 35.22100 1.000 56.76000  ? 121 LEU A HB2  1 
ATOM   1880 H  HB3  . LEU A 1 121 ? 29.07700  -20.70800 36.17700 1.000 56.76000  ? 121 LEU A HB3  1 
ATOM   1881 H  HG   . LEU A 1 121 ? 27.90600  -23.13600 35.36100 1.000 55.79000  ? 121 LEU A HG   1 
ATOM   1882 H  HD11 . LEU A 1 121 ? 28.31000  -23.93300 37.49100 1.000 62.36000  ? 121 LEU A HD11 1 
ATOM   1883 H  HD12 . LEU A 1 121 ? 29.69500  -23.47100 36.86300 1.000 62.36000  ? 121 LEU A HD12 1 
ATOM   1884 H  HD13 . LEU A 1 121 ? 28.95200  -22.54300 37.91700 1.000 62.36000  ? 121 LEU A HD13 1 
ATOM   1885 H  HD21 . LEU A 1 121 ? 26.29600  -22.63800 37.04900 1.000 58.74000  ? 121 LEU A HD21 1 
ATOM   1886 H  HD22 . LEU A 1 121 ? 26.89800  -21.16900 37.09600 1.000 58.74000  ? 121 LEU A HD22 1 
ATOM   1887 H  HD23 . LEU A 1 121 ? 26.20700  -21.70200 35.76800 1.000 58.74000  ? 121 LEU A HD23 1 
ATOM   1888 N  N    . GLN A 1 122 ? 30.31500  -19.38700 33.41200 1.000 47.84784  ? 122 GLN A N    1 
ATOM   1889 C  CA   . GLN A 1 122 ? 31.14100  -18.20400 33.19300 1.000 48.29526  ? 122 GLN A CA   1 
ATOM   1890 C  C    . GLN A 1 122 ? 30.57700  -17.26600 32.13500 1.000 53.49589  ? 122 GLN A C    1 
ATOM   1891 O  O    . GLN A 1 122 ? 31.25900  -16.28900 31.80100 1.000 52.61947  ? 122 GLN A O    1 
ATOM   1892 C  CB   . GLN A 1 122 ? 32.55600  -18.63200 32.80200 1.000 52.29838  ? 122 GLN A CB   1 
ATOM   1893 C  CG   . GLN A 1 122 ? 33.33100  -19.30100 33.92500 1.000 51.47196  ? 122 GLN A CG   1 
ATOM   1894 C  CD   . GLN A 1 122 ? 34.49900  -20.12000 33.41700 1.000 47.67414  ? 122 GLN A CD   1 
ATOM   1895 O  OE1  . GLN A 1 122 ? 35.61000  -19.61100 33.26900 1.000 48.51634  ? 122 GLN A OE1  1 
ATOM   1896 N  NE2  . GLN A 1 122 ? 34.25400  -21.39800 33.14900 1.000 47.29778  ? 122 GLN A NE2  1 
ATOM   1897 H  H    . GLN A 1 122 ? 30.65300  -20.11200 33.09900 1.000 57.53000  ? 122 GLN A H    1 
ATOM   1898 H  HA   . GLN A 1 122 ? 31.19100  -17.70600 34.02400 1.000 58.07000  ? 122 GLN A HA   1 
ATOM   1899 H  HB2  . GLN A 1 122 ? 32.49900  -19.26200 32.06600 1.000 62.87000  ? 122 GLN A HB2  1 
ATOM   1900 H  HB3  . GLN A 1 122 ? 33.05400  -17.84600 32.52700 1.000 62.87000  ? 122 GLN A HB3  1 
ATOM   1901 H  HG2  . GLN A 1 122 ? 33.67800  -18.61900 34.52000 1.000 61.88000  ? 122 GLN A HG2  1 
ATOM   1902 H  HG3  . GLN A 1 122 ? 32.73600  -19.89400 34.41000 1.000 61.88000  ? 122 GLN A HG3  1 
ATOM   1903 H  HE21 . GLN A 1 122 ? 33.46500  -21.71800 33.26600 1.000 56.87000  ? 122 GLN A HE21 1 
ATOM   1904 H  HE22 . GLN A 1 122 ? 34.88500  -21.90500 32.85800 1.000 56.87000  ? 122 GLN A HE22 1 
ATOM   1905 N  N    . GLN A 1 123 ? 29.38100  -17.51500 31.59900 1.000 48.04523  ? 123 GLN A N    1 
ATOM   1906 C  CA   . GLN A 1 123 ? 28.78100  -16.64700 30.59800 1.000 53.13005  ? 123 GLN A CA   1 
ATOM   1907 C  C    . GLN A 1 123 ? 27.40200  -16.13900 30.98900 1.000 57.46215  ? 123 GLN A C    1 
ATOM   1908 O  O    . GLN A 1 123 ? 26.78400  -15.40900 30.20400 1.000 57.88852  ? 123 GLN A O    1 
ATOM   1909 C  CB   . GLN A 1 123 ? 28.68100  -17.37900 29.25600 1.000 50.06127  ? 123 GLN A CB   1 
ATOM   1910 C  CG   . GLN A 1 123 ? 30.02200  -17.69100 28.63600 1.000 47.73730  ? 123 GLN A CG   1 
ATOM   1911 C  CD   . GLN A 1 123 ? 29.88800  -18.50500 27.37300 1.000 48.25842  ? 123 GLN A CD   1 
ATOM   1912 O  OE1  . GLN A 1 123 ? 29.53500  -17.98300 26.31700 1.000 49.97704  ? 123 GLN A OE1  1 
ATOM   1913 N  NE2  . GLN A 1 123 ? 30.15800  -19.79600 27.47700 1.000 48.30053  ? 123 GLN A NE2  1 
ATOM   1914 H  H    . GLN A 1 123 ? 28.89300  -18.19300 31.80600 1.000 57.77000  ? 123 GLN A H    1 
ATOM   1915 H  HA   . GLN A 1 123 ? 29.35800  -15.87600 30.48100 1.000 63.87000  ? 123 GLN A HA   1 
ATOM   1916 H  HB2  . GLN A 1 123 ? 28.21500  -18.21900 29.39200 1.000 60.19000  ? 123 GLN A HB2  1 
ATOM   1917 H  HB3  . GLN A 1 123 ? 28.18800  -16.82300 28.63300 1.000 60.19000  ? 123 GLN A HB3  1 
ATOM   1918 H  HG2  . GLN A 1 123 ? 30.47100  -16.86000 28.41400 1.000 57.40000  ? 123 GLN A HG2  1 
ATOM   1919 H  HG3  . GLN A 1 123 ? 30.55500  -18.19800 29.26800 1.000 57.40000  ? 123 GLN A HG3  1 
ATOM   1920 H  HE21 . GLN A 1 123 ? 30.39500  -20.12700 28.23500 1.000 58.07000  ? 123 GLN A HE21 1 
ATOM   1921 H  HE22 . GLN A 1 123 ? 30.09700  -20.30500 26.78600 1.000 58.07000  ? 123 GLN A HE22 1 
ATOM   1922 N  N    . ILE A 1 124 ? 26.89800  -16.50600 32.16400 1.000 53.41167  ? 124 ILE A N    1 
ATOM   1923 C  CA   . ILE A 1 124 ? 25.60000  -16.04800 32.63700 1.000 58.39648  ? 124 ILE A CA   1 
ATOM   1924 C  C    . ILE A 1 124 ? 25.77800  -15.42100 34.01000 1.000 58.88864  ? 124 ILE A C    1 
ATOM   1925 O  O    . ILE A 1 124 ? 26.70400  -15.75700 34.75400 1.000 60.48357  ? 124 ILE A O    1 
ATOM   1926 C  CB   . ILE A 1 124 ? 24.56900  -17.19600 32.69300 1.000 54.26966  ? 124 ILE A CB   1 
ATOM   1927 C  CG1  . ILE A 1 124 ? 25.07400  -18.32800 33.59000 1.000 53.71960  ? 124 ILE A CG1  1 
ATOM   1928 C  CG2  . ILE A 1 124 ? 24.28200  -17.71400 31.29300 1.000 50.27182  ? 124 ILE A CG2  1 
ATOM   1929 C  CD1  . ILE A 1 124 ? 24.06300  -19.43200 33.81000 1.000 53.31692  ? 124 ILE A CD1  1 
ATOM   1930 H  H    . ILE A 1 124 ? 27.30000  -17.03000 32.71500 1.000 64.21000  ? 124 ILE A H    1 
ATOM   1931 H  HA   . ILE A 1 124 ? 25.26300  -15.36900 32.03200 1.000 70.19000  ? 124 ILE A HA   1 
ATOM   1932 H  HB   . ILE A 1 124 ? 23.74600  -16.85000 33.07200 1.000 65.24000  ? 124 ILE A HB   1 
ATOM   1933 H  HG12 . ILE A 1 124 ? 25.86000  -18.72400 33.18100 1.000 64.58000  ? 124 ILE A HG12 1 
ATOM   1934 H  HG13 . ILE A 1 124 ? 25.30300  -17.96000 34.45800 1.000 64.58000  ? 124 ILE A HG13 1 
ATOM   1935 H  HG21 . ILE A 1 124 ? 23.54000  -18.33600 31.33300 1.000 60.44000  ? 124 ILE A HG21 1 
ATOM   1936 H  HG22 . ILE A 1 124 ? 24.05600  -16.96500 30.72000 1.000 60.44000  ? 124 ILE A HG22 1 
ATOM   1937 H  HG23 . ILE A 1 124 ? 25.07300  -18.16300 30.95500 1.000 60.44000  ? 124 ILE A HG23 1 
ATOM   1938 H  HD11 . ILE A 1 124 ? 24.40700  -20.04900 34.47400 1.000 64.09000  ? 124 ILE A HD11 1 
ATOM   1939 H  HD12 . ILE A 1 124 ? 23.23100  -19.04100 34.12100 1.000 64.09000  ? 124 ILE A HD12 1 
ATOM   1940 H  HD13 . ILE A 1 124 ? 23.91600  -19.89700 32.97100 1.000 64.09000  ? 124 ILE A HD13 1 
ATOM   1941 N  N    . GLU A 1 125 ? 24.88300  -14.49600 34.34100 1.000 61.08627  ? 125 GLU A N    1 
ATOM   1942 C  CA   . GLU A 1 125 ? 24.87000  -13.89200 35.66600 1.000 64.21033  ? 125 GLU A CA   1 
ATOM   1943 C  C    . GLU A 1 125 ? 24.25300  -14.87800 36.65000 1.000 60.47830  ? 125 GLU A C    1 
ATOM   1944 O  O    . GLU A 1 125 ? 23.10200  -15.29600 36.47900 1.000 58.02538  ? 125 GLU A O    1 
ATOM   1945 C  CB   . GLU A 1 125 ? 24.09000  -12.58100 35.65000 1.000 66.63694  ? 125 GLU A CB   1 
ATOM   1946 C  CG   . GLU A 1 125 ? 24.43300  -11.64600 36.80100 1.000 79.40426  ? 125 GLU A CG   1 
ATOM   1947 C  CD   . GLU A 1 125 ? 24.14600  -10.19300 36.47500 1.000 95.03508  ? 125 GLU A CD   1 
ATOM   1948 O  OE1  . GLU A 1 125 ? 23.05100  -9.90500  35.94700 1.000 102.53335 ? 125 GLU A OE1  1 
ATOM   1949 O  OE2  . GLU A 1 125 ? 25.01700  -9.33900  36.74800 1.000 95.48776  ? 125 GLU A OE2  1 
ATOM   1950 H  H    . GLU A 1 125 ? 24.27100  -14.20000 33.81300 1.000 73.42000  ? 125 GLU A H    1 
ATOM   1951 H  HA   . GLU A 1 125 ? 25.77700  -13.69400 35.94600 1.000 77.17000  ? 125 GLU A HA   1 
ATOM   1952 H  HB2  . GLU A 1 125 ? 24.28300  -12.11400 34.82200 1.000 80.08000  ? 125 GLU A HB2  1 
ATOM   1953 H  HB3  . GLU A 1 125 ? 23.14300  -12.78200 35.70500 1.000 80.08000  ? 125 GLU A HB3  1 
ATOM   1954 H  HG2  . GLU A 1 125 ? 23.90400  -11.89000 37.57600 1.000 95.40000  ? 125 GLU A HG2  1 
ATOM   1955 H  HG3  . GLU A 1 125 ? 25.37800  -11.72800 37.00400 1.000 95.40000  ? 125 GLU A HG3  1 
ATOM   1956 N  N    . LEU A 1 126 ? 25.01800  -15.25800 37.67200 1.000 59.25184  ? 126 LEU A N    1 
ATOM   1957 C  CA   . LEU A 1 126 ? 24.54400  -16.22400 38.65500 1.000 58.74125  ? 126 LEU A CA   1 
ATOM   1958 C  C    . LEU A 1 126 ? 25.41300  -16.12500 39.89900 1.000 58.58071  ? 126 LEU A C    1 
ATOM   1959 O  O    . LEU A 1 126 ? 26.64300  -16.10400 39.79800 1.000 60.79676  ? 126 LEU A O    1 
ATOM   1960 C  CB   . LEU A 1 126 ? 24.57800  -17.64900 38.09100 1.000 50.96401  ? 126 LEU A CB   1 
ATOM   1961 C  CG   . LEU A 1 126 ? 23.81100  -18.69500 38.90200 1.000 53.89857  ? 126 LEU A CG   1 
ATOM   1962 C  CD1  . LEU A 1 126 ? 22.32000  -18.60500 38.62300 1.000 53.63801  ? 126 LEU A CD1  1 
ATOM   1963 C  CD2  . LEU A 1 126 ? 24.32700  -20.09400 38.60600 1.000 54.49074  ? 126 LEU A CD2  1 
ATOM   1964 H  H    . LEU A 1 126 ? 25.81500  -14.97000 37.81600 1.000 71.21000  ? 126 LEU A H    1 
ATOM   1965 H  HA   . LEU A 1 126 ? 23.63000  -16.01300 38.90200 1.000 70.60000  ? 126 LEU A HA   1 
ATOM   1966 H  HB2  . LEU A 1 126 ? 24.19300  -17.63400 37.20100 1.000 61.27000  ? 126 LEU A HB2  1 
ATOM   1967 H  HB3  . LEU A 1 126 ? 25.50300  -17.93800 38.04800 1.000 61.27000  ? 126 LEU A HB3  1 
ATOM   1968 H  HG   . LEU A 1 126 ? 23.95100  -18.52000 39.84500 1.000 64.79000  ? 126 LEU A HG   1 
ATOM   1969 H  HD11 . LEU A 1 126 ? 21.85900  -19.27300 39.15400 1.000 64.48000  ? 126 LEU A HD11 1 
ATOM   1970 H  HD12 . LEU A 1 126 ? 22.00800  -17.71900 38.86100 1.000 64.48000  ? 126 LEU A HD12 1 
ATOM   1971 H  HD13 . LEU A 1 126 ? 22.16500  -18.76900 37.67900 1.000 64.48000  ? 126 LEU A HD13 1 
ATOM   1972 H  HD21 . LEU A 1 126 ? 23.80200  -20.73700 39.11000 1.000 65.50000  ? 126 LEU A HD21 1 
ATOM   1973 H  HD22 . LEU A 1 126 ? 24.24000  -20.26800 37.65600 1.000 65.50000  ? 126 LEU A HD22 1 
ATOM   1974 H  HD23 . LEU A 1 126 ? 25.25900  -20.14900 38.86900 1.000 65.50000  ? 126 LEU A HD23 1 
ATOM   1975 N  N    . LYS A 1 127 ? 24.77000  -16.06700 41.06200 1.000 59.25710  ? 127 LYS A N    1 
ATOM   1976 C  CA   . LYS A 1 127 ? 25.45400  -16.00600 42.34600 1.000 56.83839  ? 127 LYS A CA   1 
ATOM   1977 C  C    . LYS A 1 127 ? 24.99000  -17.17300 43.20400 1.000 49.03746  ? 127 LYS A C    1 
ATOM   1978 O  O    . LYS A 1 127 ? 23.78600  -17.35100 43.41900 1.000 50.26129  ? 127 LYS A O    1 
ATOM   1979 C  CB   . LYS A 1 127 ? 25.18000  -14.68100 43.06400 1.000 57.09369  ? 127 LYS A CB   1 
ATOM   1980 C  CG   . LYS A 1 127 ? 25.41600  -13.44100 42.21100 1.000 72.76662  ? 127 LYS A CG   1 
ATOM   1981 C  CD   . LYS A 1 127 ? 26.85500  -12.95000 42.32900 1.000 82.84414  ? 127 LYS A CD   1 
ATOM   1982 C  CE   . LYS A 1 127 ? 27.17200  -11.81800 41.35100 1.000 85.82608  ? 127 LYS A CE   1 
ATOM   1983 N  NZ   . LYS A 1 127 ? 26.35300  -11.84300 40.10300 1.000 84.37327  ? 127 LYS A NZ   1 
ATOM   1984 H  H    . LYS A 1 127 ? 23.91300  -16.06000 41.13300 1.000 71.22000  ? 127 LYS A H    1 
ATOM   1985 H  HA   . LYS A 1 127 ? 26.41200  -16.08000 42.20900 1.000 68.32000  ? 127 LYS A HA   1 
ATOM   1986 H  HB2  . LYS A 1 127 ? 24.25200  -14.67000 43.34700 1.000 68.63000  ? 127 LYS A HB2  1 
ATOM   1987 H  HB3  . LYS A 1 127 ? 25.76300  -14.62100 43.83600 1.000 68.63000  ? 127 LYS A HB3  1 
ATOM   1988 H  HG2  . LYS A 1 127 ? 25.24000  -13.65200 41.28100 1.000 87.43000  ? 127 LYS A HG2  1 
ATOM   1989 H  HG3  . LYS A 1 127 ? 24.82600  -12.73000 42.50700 1.000 87.43000  ? 127 LYS A HG3  1 
ATOM   1990 H  HD2  . LYS A 1 127 ? 27.00500  -12.62000 43.22900 1.000 99.53000  ? 127 LYS A HD2  1 
ATOM   1991 H  HD3  . LYS A 1 127 ? 27.45800  -13.68700 42.14100 1.000 99.53000  ? 127 LYS A HD3  1 
ATOM   1992 H  HE2  . LYS A 1 127 ? 27.00800  -10.97000 41.79200 1.000 103.10000 ? 127 LYS A HE2  1 
ATOM   1993 H  HE3  . LYS A 1 127 ? 28.10400  -11.88200 41.09200 1.000 103.10000 ? 127 LYS A HE3  1 
ATOM   1994 H  HZ1  . LYS A 1 127 ? 26.60500  -11.18400 39.56000 1.000 101.36000 ? 127 LYS A HZ1  1 
ATOM   1995 H  HZ2  . LYS A 1 127 ? 26.46200  -12.62100 39.68300 1.000 101.36000 ? 127 LYS A HZ2  1 
ATOM   1996 H  HZ3  . LYS A 1 127 ? 25.49200  -11.74100 40.30200 1.000 101.36000 ? 127 LYS A HZ3  1 
ATOM   1997 N  N    . PHE A 1 128 ? 25.94000  -17.96300 43.69000 1.000 52.02729  ? 128 PHE A N    1 
ATOM   1998 C  CA   . PHE A 1 128 ? 25.61400  -19.11200 44.51600 1.000 48.80059  ? 128 PHE A CA   1 
ATOM   1999 C  C    . PHE A 1 128 ? 25.35300  -18.67900 45.95400 1.000 51.36932  ? 128 PHE A C    1 
ATOM   2000 O  O    . PHE A 1 128 ? 25.86000  -17.65500 46.42000 1.000 48.03997  ? 128 PHE A O    1 
ATOM   2001 C  CB   . PHE A 1 128 ? 26.74600  -20.13600 44.47200 1.000 48.54529  ? 128 PHE A CB   1 
ATOM   2002 C  CG   . PHE A 1 128 ? 26.87700  -20.83300 43.14800 1.000 50.10601  ? 128 PHE A CG   1 
ATOM   2003 C  CD1  . PHE A 1 128 ? 25.89600  -21.70800 42.71200 1.000 50.49816  ? 128 PHE A CD1  1 
ATOM   2004 C  CD2  . PHE A 1 128 ? 27.97900  -20.61400 42.33900 1.000 50.99822  ? 128 PHE A CD2  1 
ATOM   2005 C  CE1  . PHE A 1 128 ? 26.01200  -22.35100 41.49500 1.000 48.86375  ? 128 PHE A CE1  1 
ATOM   2006 C  CE2  . PHE A 1 128 ? 28.10000  -21.25600 41.12000 1.000 45.69758  ? 128 PHE A CE2  1 
ATOM   2007 C  CZ   . PHE A 1 128 ? 27.11500  -22.12500 40.69900 1.000 45.85287  ? 128 PHE A CZ   1 
ATOM   2008 H  H    . PHE A 1 128 ? 26.78200  -17.85300 43.55300 1.000 62.55000  ? 128 PHE A H    1 
ATOM   2009 H  HA   . PHE A 1 128 ? 24.81000  -19.53900 44.18100 1.000 58.67000  ? 128 PHE A HA   1 
ATOM   2010 H  HB2  . PHE A 1 128 ? 27.58500  -19.68300 44.65200 1.000 58.37000  ? 128 PHE A HB2  1 
ATOM   2011 H  HB3  . PHE A 1 128 ? 26.58300  -20.81200 45.14800 1.000 58.37000  ? 128 PHE A HB3  1 
ATOM   2012 H  HD1  . PHE A 1 128 ? 25.15000  -21.86400 43.24600 1.000 60.71000  ? 128 PHE A HD1  1 
ATOM   2013 H  HD2  . PHE A 1 128 ? 28.64500  -20.02800 42.61800 1.000 61.31000  ? 128 PHE A HD2  1 
ATOM   2014 H  HE1  . PHE A 1 128 ? 25.34700  -22.93600 41.21200 1.000 58.75000  ? 128 PHE A HE1  1 
ATOM   2015 H  HE2  . PHE A 1 128 ? 28.84500  -21.10300 40.58500 1.000 54.95000  ? 128 PHE A HE2  1 
ATOM   2016 H  HZ   . PHE A 1 128 ? 27.19500  -22.55700 39.87900 1.000 55.14000  ? 128 PHE A HZ   1 
ATOM   2017 N  N    . ASN A 1 129 ? 24.54600  -19.47500 46.65600 1.000 50.08758  ? 129 ASN A N    1 
ATOM   2018 C  CA   . ASN A 1 129 ? 24.19600  -19.18200 48.04000 1.000 49.95862  ? 129 ASN A CA   1 
ATOM   2019 C  C    . ASN A 1 129 ? 25.15200  -19.87500 49.00900 1.000 50.34814  ? 129 ASN A C    1 
ATOM   2020 O  O    . ASN A 1 129 ? 25.66600  -19.22400 49.92600 1.000 50.52711  ? 129 ASN A O    1 
ATOM   2021 C  CB   . ASN A 1 129 ? 22.75100  -19.59600 48.32700 1.000 52.44313  ? 129 ASN A CB   1 
ATOM   2022 C  CG   . ASN A 1 129 ? 21.73900  -18.68400 47.65400 1.000 58.87285  ? 129 ASN A CG   1 
ATOM   2023 O  OD1  . ASN A 1 129 ? 22.00800  -17.50500 47.41700 1.000 53.99332  ? 129 ASN A OD1  1 
ATOM   2024 N  ND2  . ASN A 1 129 ? 20.57000  -19.22800 47.33900 1.000 60.45725  ? 129 ASN A ND2  1 
ATOM   2025 H  H    . ASN A 1 129 ? 24.18800  -20.19400 46.34900 1.000 60.22000  ? 129 ASN A H    1 
ATOM   2026 H  HA   . ASN A 1 129 ? 24.28100  -18.22700 48.18500 1.000 60.07000  ? 129 ASN A HA   1 
ATOM   2027 H  HB2  . ASN A 1 129 ? 22.60800  -20.49700 47.99800 1.000 63.04000  ? 129 ASN A HB2  1 
ATOM   2028 H  HB3  . ASN A 1 129 ? 22.59600  -19.56300 49.28400 1.000 63.04000  ? 129 ASN A HB3  1 
ATOM   2029 H  HD21 . ASN A 1 129 ? 19.96400  -18.75300 46.95700 1.000 72.66000  ? 129 ASN A HD21 1 
ATOM   2030 H  HD22 . ASN A 1 129 ? 20.41900  -20.05600 47.51700 1.000 72.66000  ? 129 ASN A HD22 1 
ATOM   2031 N  N    . PRO A 1 130 ? 25.42600  -21.16900 48.85300 1.000 48.75321  ? 130 PRO A N    1 
ATOM   2032 C  CA   . PRO A 1 130 ? 26.32700  -21.84400 49.79600 1.000 49.58489  ? 130 PRO A CA   1 
ATOM   2033 C  C    . PRO A 1 130 ? 27.72900  -21.27200 49.70800 1.000 49.91125  ? 130 PRO A C    1 
ATOM   2034 O  O    . PRO A 1 130 ? 28.31600  -21.22100 48.61700 1.000 49.74544  ? 130 PRO A O    1 
ATOM   2035 C  CB   . PRO A 1 130 ? 26.29500  -23.31300 49.34000 1.000 51.73778  ? 130 PRO A CB   1 
ATOM   2036 C  CG   . PRO A 1 130 ? 25.12300  -23.42700 48.42200 1.000 53.99068  ? 130 PRO A CG   1 
ATOM   2037 C  CD   . PRO A 1 130 ? 24.97500  -22.08400 47.78900 1.000 50.25866  ? 130 PRO A CD   1 
ATOM   2038 H  HA   . PRO A 1 130 ? 25.99400  -21.77600 50.70400 1.000 59.61000  ? 130 PRO A HA   1 
ATOM   2039 H  HB2  . PRO A 1 130 ? 27.11800  -23.53000 48.87500 1.000 62.20000  ? 130 PRO A HB2  1 
ATOM   2040 H  HB3  . PRO A 1 130 ? 26.18700  -23.89300 50.11000 1.000 62.20000  ? 130 PRO A HB3  1 
ATOM   2041 H  HG2  . PRO A 1 130 ? 25.29700  -24.10600 47.75200 1.000 64.90000  ? 130 PRO A HG2  1 
ATOM   2042 H  HG3  . PRO A 1 130 ? 24.33000  -23.65700 48.93100 1.000 64.90000  ? 130 PRO A HG3  1 
ATOM   2043 H  HD2  . PRO A 1 130 ? 25.53800  -22.00600 47.00300 1.000 60.42000  ? 130 PRO A HD2  1 
ATOM   2044 H  HD3  . PRO A 1 130 ? 24.05000  -21.91200 47.55300 1.000 60.42000  ? 130 PRO A HD3  1 
ATOM   2045 N  N    . PRO A 1 131 ? 28.30300  -20.82700 50.83000 1.000 46.67402  ? 131 PRO A N    1 
ATOM   2046 C  CA   . PRO A 1 131 ? 29.68300  -20.31500 50.78300 1.000 47.90838  ? 131 PRO A CA   1 
ATOM   2047 C  C    . PRO A 1 131 ? 30.66600  -21.28200 50.15100 1.000 47.59255  ? 131 PRO A C    1 
ATOM   2048 O  O    . PRO A 1 131 ? 31.67200  -20.84400 49.57800 1.000 49.23222  ? 131 PRO A O    1 
ATOM   2049 C  CB   . PRO A 1 131 ? 30.01000  -20.06100 52.26200 1.000 53.09584  ? 131 PRO A CB   1 
ATOM   2050 C  CG   . PRO A 1 131 ? 28.69100  -19.81600 52.90200 1.000 49.45593  ? 131 PRO A CG   1 
ATOM   2051 C  CD   . PRO A 1 131 ? 27.71100  -20.69500 52.17500 1.000 52.84055  ? 131 PRO A CD   1 
ATOM   2052 H  HA   . PRO A 1 131 ? 29.70600  -19.47400 50.30100 1.000 57.61000  ? 131 PRO A HA   1 
ATOM   2053 H  HB2  . PRO A 1 131 ? 30.44400  -20.84000 52.64400 1.000 63.83000  ? 131 PRO A HB2  1 
ATOM   2054 H  HB3  . PRO A 1 131 ? 30.58700  -19.28600 52.34500 1.000 63.83000  ? 131 PRO A HB3  1 
ATOM   2055 H  HG2  . PRO A 1 131 ? 28.73400  -20.05400 53.84200 1.000 59.46000  ? 131 PRO A HG2  1 
ATOM   2056 H  HG3  . PRO A 1 131 ? 28.45000  -18.88100 52.80800 1.000 59.46000  ? 131 PRO A HG3  1 
ATOM   2057 H  HD2  . PRO A 1 131 ? 27.63800  -21.56000 52.60600 1.000 63.52000  ? 131 PRO A HD2  1 
ATOM   2058 H  HD3  . PRO A 1 131 ? 26.83800  -20.27300 52.12700 1.000 63.52000  ? 131 PRO A HD3  1 
ATOM   2059 N  N    . ALA A 1 132 ? 30.41000  -22.58900 50.23700 1.000 47.42148  ? 132 ALA A N    1 
ATOM   2060 C  CA   . ALA A 1 132 ? 31.29100  -23.55800 49.59300 1.000 49.77439  ? 132 ALA A CA   1 
ATOM   2061 C  C    . ALA A 1 132 ? 31.36200  -23.31500 48.09100 1.000 44.17635  ? 132 ALA A C    1 
ATOM   2062 O  O    . ALA A 1 132 ? 32.45000  -23.28500 47.50500 1.000 47.22408  ? 132 ALA A O    1 
ATOM   2063 C  CB   . ALA A 1 132 ? 30.81000  -24.97900 49.88600 1.000 49.05588  ? 132 ALA A CB   1 
ATOM   2064 H  H    . ALA A 1 132 ? 29.74200  -22.93400 50.65500 1.000 57.02000  ? 132 ALA A H    1 
ATOM   2065 H  HA   . ALA A 1 132 ? 32.18400  -23.46100 49.96000 1.000 59.84000  ? 132 ALA A HA   1 
ATOM   2066 H  HB1  . ALA A 1 132 ? 31.41900  -25.61100 49.47200 1.000 58.98000  ? 132 ALA A HB1  1 
ATOM   2067 H  HB2  . ALA A 1 132 ? 30.79400  -25.11600 50.84600 1.000 58.98000  ? 132 ALA A HB2  1 
ATOM   2068 H  HB3  . ALA A 1 132 ? 29.91800  -25.09200 49.52100 1.000 58.98000  ? 132 ALA A HB3  1 
ATOM   2069 N  N    . LEU A 1 133 ? 30.20500  -23.13700 47.44900 1.000 44.72378  ? 133 LEU A N    1 
ATOM   2070 C  CA   . LEU A 1 133 ? 30.18800  -22.90200 46.00900 1.000 47.65571  ? 133 LEU A CA   1 
ATOM   2071 C  C    . LEU A 1 133 ? 30.75800  -21.53100 45.66500 1.000 50.04021  ? 133 LEU A C    1 
ATOM   2072 O  O    . LEU A 1 133 ? 31.49800  -21.39000 44.68500 1.000 51.22456  ? 133 LEU A O    1 
ATOM   2073 C  CB   . LEU A 1 133 ? 28.76400  -23.04100 45.47300 1.000 46.31608  ? 133 LEU A CB   1 
ATOM   2074 C  CG   . LEU A 1 133 ? 28.21300  -24.46700 45.41000 1.000 42.54194  ? 133 LEU A CG   1 
ATOM   2075 C  CD1  . LEU A 1 133 ? 26.73500  -24.45000 45.06100 1.000 45.55546  ? 133 LEU A CD1  1 
ATOM   2076 C  CD2  . LEU A 1 133 ? 28.98700  -25.30500 44.40500 1.000 45.85813  ? 133 LEU A CD2  1 
ATOM   2077 H  H    . LEU A 1 133 ? 29.42900  -23.14700 47.82000 1.000 53.78000  ? 133 LEU A H    1 
ATOM   2078 H  HA   . LEU A 1 133 ? 30.73900  -23.57300 45.57700 1.000 57.30000  ? 133 LEU A HA   1 
ATOM   2079 H  HB2  . LEU A 1 133 ? 28.17300  -22.52900 46.04700 1.000 55.69000  ? 133 LEU A HB2  1 
ATOM   2080 H  HB3  . LEU A 1 133 ? 28.74300  -22.68400 44.57200 1.000 55.69000  ? 133 LEU A HB3  1 
ATOM   2081 H  HG   . LEU A 1 133 ? 28.31600  -24.87900 46.28200 1.000 51.16000  ? 133 LEU A HG   1 
ATOM   2082 H  HD11 . LEU A 1 133 ? 26.39000  -25.35600 45.10300 1.000 54.78000  ? 133 LEU A HD11 1 
ATOM   2083 H  HD12 . LEU A 1 133 ? 26.26600  -23.88800 45.69900 1.000 54.78000  ? 133 LEU A HD12 1 
ATOM   2084 H  HD13 . LEU A 1 133 ? 26.62500  -24.09500 44.16500 1.000 54.78000  ? 133 LEU A HD13 1 
ATOM   2085 H  HD21 . LEU A 1 133 ? 28.52100  -26.14500 44.27000 1.000 55.14000  ? 133 LEU A HD21 1 
ATOM   2086 H  HD22 . LEU A 1 133 ? 29.04400  -24.82000 43.56600 1.000 55.14000  ? 133 LEU A HD22 1 
ATOM   2087 H  HD23 . LEU A 1 133 ? 29.87700  -25.47200 44.75200 1.000 55.14000  ? 133 LEU A HD23 1 
ATOM   2088 N  N    . GLN A 1 134 ? 30.41700  -20.50700 46.45100 1.000 46.83193  ? 134 GLN A N    1 
ATOM   2089 C  CA   . GLN A 1 134 ? 30.99800  -19.18600 46.24600 1.000 44.77642  ? 134 GLN A CA   1 
ATOM   2090 C  C    . GLN A 1 134 ? 32.51900  -19.26800 46.20100 1.000 52.36417  ? 134 GLN A C    1 
ATOM   2091 O  O    . GLN A 1 134 ? 33.15400  -18.86700 45.21900 1.000 49.44803  ? 134 GLN A O    1 
ATOM   2092 C  CB   . GLN A 1 134 ? 30.55400  -18.23800 47.36300 1.000 50.88242  ? 134 GLN A CB   1 
ATOM   2093 C  CG   . GLN A 1 134 ? 29.11000  -17.76300 47.27500 1.000 51.56671  ? 134 GLN A CG   1 
ATOM   2094 C  CD   . GLN A 1 134 ? 28.65100  -17.08200 48.55800 1.000 54.09333  ? 134 GLN A CD   1 
ATOM   2095 O  OE1  . GLN A 1 134 ? 29.46500  -16.75500 49.42200 1.000 54.81184  ? 134 GLN A OE1  1 
ATOM   2096 N  NE2  . GLN A 1 134 ? 27.34500  -16.87000 48.68900 1.000 53.87225  ? 134 GLN A NE2  1 
ATOM   2097 H  H    . GLN A 1 134 ? 29.85700  -20.55400 47.10300 1.000 56.31000  ? 134 GLN A H    1 
ATOM   2098 H  HA   . GLN A 1 134 ? 30.67800  -18.83200 45.40200 1.000 53.85000  ? 134 GLN A HA   1 
ATOM   2099 H  HB2  . GLN A 1 134 ? 30.65800  -18.69500 48.21200 1.000 61.17000  ? 134 GLN A HB2  1 
ATOM   2100 H  HB3  . GLN A 1 134 ? 31.12000  -17.45000 47.33800 1.000 61.17000  ? 134 GLN A HB3  1 
ATOM   2101 H  HG2  . GLN A 1 134 ? 29.02700  -17.12500 46.54900 1.000 61.99000  ? 134 GLN A HG2  1 
ATOM   2102 H  HG3  . GLN A 1 134 ? 28.53300  -18.52500 47.11500 1.000 61.99000  ? 134 GLN A HG3  1 
ATOM   2103 H  HE21 . GLN A 1 134 ? 26.80600  -17.11500 48.06600 1.000 64.76000  ? 134 GLN A HE21 1 
ATOM   2104 H  HE22 . GLN A 1 134 ? 27.04000  -16.48900 49.39700 1.000 64.76000  ? 134 GLN A HE22 1 
ATOM   2105 N  N    . ASP A 1 135 ? 33.11900  -19.79900 47.27100 1.000 50.11390  ? 135 ASP A N    1 
ATOM   2106 C  CA   . ASP A 1 135 ? 34.57400  -19.86400 47.36100 1.000 46.92668  ? 135 ASP A CA   1 
ATOM   2107 C  C    . ASP A 1 135 ? 35.16100  -20.68800 46.22200 1.000 48.31895  ? 135 ASP A C    1 
ATOM   2108 O  O    . ASP A 1 135 ? 36.12800  -20.27200 45.57400 1.000 48.54793  ? 135 ASP A O    1 
ATOM   2109 C  CB   . ASP A 1 135 ? 34.98300  -20.45200 48.71100 1.000 51.18508  ? 135 ASP A CB   1 
ATOM   2110 C  CG   . ASP A 1 135 ? 34.63400  -19.54300 49.87400 1.000 54.96975  ? 135 ASP A CG   1 
ATOM   2111 O  OD1  . ASP A 1 135 ? 34.07700  -18.45200 49.62800 1.000 53.64064  ? 135 ASP A OD1  1 
ATOM   2112 O  OD2  . ASP A 1 135 ? 34.91200  -19.92300 51.03200 1.000 53.87225  ? 135 ASP A OD2  1 
ATOM   2113 H  H    . ASP A 1 135 ? 32.70700  -20.12500 47.95200 1.000 60.25000  ? 135 ASP A H    1 
ATOM   2114 H  HA   . ASP A 1 135 ? 34.93100  -18.96500 47.29600 1.000 56.43000  ? 135 ASP A HA   1 
ATOM   2115 H  HB2  . ASP A 1 135 ? 34.52300  -21.29600 48.84200 1.000 61.54000  ? 135 ASP A HB2  1 
ATOM   2116 H  HB3  . ASP A 1 135 ? 35.94300  -20.59300 48.71800 1.000 61.54000  ? 135 ASP A HB3  1 
ATOM   2117 N  N    . ALA A 1 136 ? 34.58800  -21.86600 45.96200 1.000 46.53189  ? 136 ALA A N    1 
ATOM   2118 C  CA   . ALA A 1 136 ? 35.14300  -22.74400 44.93700 1.000 48.66636  ? 136 ALA A CA   1 
ATOM   2119 C  C    . ALA A 1 136 ? 34.95400  -22.16100 43.54100 1.000 48.70847  ? 136 ALA A C    1 
ATOM   2120 O  O    . ALA A 1 136 ? 35.85500  -22.24900 42.69900 1.000 49.07957  ? 136 ALA A O    1 
ATOM   2121 C  CB   . ALA A 1 136 ? 34.50100  -24.12700 45.02900 1.000 49.90862  ? 136 ALA A CB   1 
ATOM   2122 H  H    . ALA A 1 136 ? 33.88900  -22.17300 46.35900 1.000 55.95000  ? 136 ALA A H    1 
ATOM   2123 H  HA   . ALA A 1 136 ? 36.09500  -22.84000 45.09500 1.000 58.51000  ? 136 ALA A HA   1 
ATOM   2124 H  HB1  . ALA A 1 136 ? 34.88700  -24.70100 44.34800 1.000 60.00000  ? 136 ALA A HB1  1 
ATOM   2125 H  HB2  . ALA A 1 136 ? 34.67100  -24.49700 45.90900 1.000 60.00000  ? 136 ALA A HB2  1 
ATOM   2126 H  HB3  . ALA A 1 136 ? 33.54500  -24.04200 44.88500 1.000 60.00000  ? 136 ALA A HB3  1 
ATOM   2127 N  N    . TYR A 1 137 ? 33.79000  -21.56500 43.27400 1.000 48.55845  ? 137 TYR A N    1 
ATOM   2128 C  CA   . TYR A 1 137 ? 33.55500  -20.98400 41.95700 1.000 50.60344  ? 137 TYR A CA   1 
ATOM   2129 C  C    . TYR A 1 137 ? 34.51900  -19.83700 41.68700 1.000 50.07179  ? 137 TYR A C    1 
ATOM   2130 O  O    . TYR A 1 137 ? 35.03800  -19.70100 40.57300 1.000 50.62712  ? 137 TYR A O    1 
ATOM   2131 C  CB   . TYR A 1 137 ? 32.10900  -20.50400 41.84100 1.000 51.48512  ? 137 TYR A CB   1 
ATOM   2132 C  CG   . TYR A 1 137 ? 31.74800  -20.00000 40.46200 1.000 52.14836  ? 137 TYR A CG   1 
ATOM   2133 C  CD1  . TYR A 1 137 ? 32.05500  -20.74300 39.32900 1.000 53.33271  ? 137 TYR A CD1  1 
ATOM   2134 C  CD2  . TYR A 1 137 ? 31.10400  -18.78300 40.29200 1.000 56.88314  ? 137 TYR A CD2  1 
ATOM   2135 C  CE1  . TYR A 1 137 ? 31.73200  -20.28800 38.06800 1.000 52.38260  ? 137 TYR A CE1  1 
ATOM   2136 C  CE2  . TYR A 1 137 ? 30.77400  -18.32100 39.03200 1.000 61.57054  ? 137 TYR A CE2  1 
ATOM   2137 C  CZ   . TYR A 1 137 ? 31.09100  -19.07800 37.92400 1.000 57.55164  ? 137 TYR A CZ   1 
ATOM   2138 O  OH   . TYR A 1 137 ? 30.76600  -18.62200 36.66600 1.000 62.37064  ? 137 TYR A OH   1 
ATOM   2139 H  H    . TYR A 1 137 ? 33.13600  -21.48700 43.82600 1.000 58.38000  ? 137 TYR A H    1 
ATOM   2140 H  HA   . TYR A 1 137 ? 33.69700  -21.66700 41.28300 1.000 60.84000  ? 137 TYR A HA   1 
ATOM   2141 H  HB2  . TYR A 1 137 ? 31.51700  -21.24300 42.05100 1.000 61.89000  ? 137 TYR A HB2  1 
ATOM   2142 H  HB3  . TYR A 1 137 ? 31.96900  -19.77800 42.46800 1.000 61.89000  ? 137 TYR A HB3  1 
ATOM   2143 H  HD1  . TYR A 1 137 ? 32.48600  -21.56100 39.42300 1.000 64.11000  ? 137 TYR A HD1  1 
ATOM   2144 H  HD2  . TYR A 1 137 ? 30.89000  -18.27100 41.03800 1.000 68.37000  ? 137 TYR A HD2  1 
ATOM   2145 H  HE1  . TYR A 1 137 ? 31.94500  -20.79600 37.31800 1.000 62.97000  ? 137 TYR A HE1  1 
ATOM   2146 H  HE2  . TYR A 1 137 ? 30.34200  -17.50300 38.93200 1.000 74.00000  ? 137 TYR A HE2  1 
ATOM   2147 H  HH   . TYR A 1 137 ? 30.32700  -17.90900 36.72400 1.000 74.96000  ? 137 TYR A HH   1 
ATOM   2148 N  N    . TYR A 1 138 ? 34.77200  -19.00100 42.69500 1.000 49.36908  ? 138 TYR A N    1 
ATOM   2149 C  CA   . TYR A 1 138 ? 35.74800  -17.93000 42.53400 1.000 49.66122  ? 138 TYR A CA   1 
ATOM   2150 C  C    . TYR A 1 138 ? 37.11300  -18.49200 42.15800 1.000 52.95109  ? 138 TYR A C    1 
ATOM   2151 O  O    . TYR A 1 138 ? 37.83100  -17.90700 41.33800 1.000 59.19394  ? 138 TYR A O    1 
ATOM   2152 C  CB   . TYR A 1 138 ? 35.83800  -17.10700 43.82000 1.000 53.39851  ? 138 TYR A CB   1 
ATOM   2153 C  CG   . TYR A 1 138 ? 36.84900  -15.98300 43.76800 1.000 54.35125  ? 138 TYR A CG   1 
ATOM   2154 C  CD1  . TYR A 1 138 ? 38.19300  -16.21500 44.03200 1.000 58.84127  ? 138 TYR A CD1  1 
ATOM   2155 C  CD2  . TYR A 1 138 ? 36.45700  -14.68600 43.46700 1.000 56.99894  ? 138 TYR A CD2  1 
ATOM   2156 C  CE1  . TYR A 1 138 ? 39.11700  -15.18900 43.98800 1.000 55.72773  ? 138 TYR A CE1  1 
ATOM   2157 C  CE2  . TYR A 1 138 ? 37.37500  -13.65300 43.42300 1.000 57.17791  ? 138 TYR A CE2  1 
ATOM   2158 C  CZ   . TYR A 1 138 ? 38.70300  -13.91100 43.68400 1.000 55.76195  ? 138 TYR A CZ   1 
ATOM   2159 O  OH   . TYR A 1 138 ? 39.61900  -12.88500 43.64000 1.000 68.80035  ? 138 TYR A OH   1 
ATOM   2160 H  H    . TYR A 1 138 ? 34.39800  -19.03300 43.46900 1.000 59.36000  ? 138 TYR A H    1 
ATOM   2161 H  HA   . TYR A 1 138 ? 35.45800  -17.33900 41.82100 1.000 59.71000  ? 138 TYR A HA   1 
ATOM   2162 H  HB2  . TYR A 1 138 ? 34.96900  -16.71400 43.99700 1.000 64.19000  ? 138 TYR A HB2  1 
ATOM   2163 H  HB3  . TYR A 1 138 ? 36.09000  -17.69600 44.54800 1.000 64.19000  ? 138 TYR A HB3  1 
ATOM   2164 H  HD1  . TYR A 1 138 ? 38.47500  -17.07600 44.24100 1.000 68.51000  ? 138 TYR A HD1  1 
ATOM   2165 H  HD2  . TYR A 1 138 ? 35.56100  -14.50900 43.29300 1.000 70.72000  ? 138 TYR A HD2  1 
ATOM   2166 H  HE1  . TYR A 1 138 ? 40.01500  -15.36100 44.16200 1.000 68.73000  ? 138 TYR A HE1  1 
ATOM   2167 H  HE2  . TYR A 1 138 ? 37.09800  -12.78900 43.21800 1.000 66.99000  ? 138 TYR A HE2  1 
ATOM   2168 H  HH   . TYR A 1 138 ? 40.38700  -13.17800 43.81600 1.000 82.67000  ? 138 TYR A HH   1 
ATOM   2169 N  N    . ARG A 1 139 ? 37.55800  -19.53100 42.66300 1.000 50.97453  ? 139 ARG A N    1 
ATOM   2170 C  CA   . ARG A 1 139 ? 38.87100  -20.13100 42.34000 1.000 54.36441  ? 139 ARG A CA   1 
ATOM   2171 C  C    . ARG A 1 139 ? 38.78700  -20.84900 40.99900 1.000 54.43021  ? 139 ARG A C    1 
ATOM   2172 O  O    . ARG A 1 139 ? 39.76700  -20.83400 40.32200 1.000 52.48787  ? 139 ARG A O    1 
ATOM   2173 C  CB   . ARG A 1 139 ? 39.28200  -21.12700 43.41800 1.000 57.72797  ? 139 ARG A CB   1 
ATOM   2174 C  CG   . ARG A 1 139 ? 39.52500  -20.48500 44.77100 1.000 64.39719  ? 139 ARG A CG   1 
ATOM   2175 C  CD   . ARG A 1 139 ? 39.83500  -21.51500 45.83200 1.000 74.25890  ? 139 ARG A CD   1 
ATOM   2176 N  NE   . ARG A 1 139 ? 41.07200  -22.23200 45.56900 1.000 76.23282  ? 139 ARG A NE   1 
ATOM   2177 C  CZ   . ARG A 1 139 ? 41.50800  -23.26000 46.28200 1.000 76.73288  ? 139 ARG A CZ   1 
ATOM   2178 N  NH1  . ARG A 1 139 ? 41.97300  -23.06600 47.50100 1.000 75.25376  ? 139 ARG A NH1  1 
ATOM   2179 N  NH2  . ARG A 1 139 ? 41.45200  -24.48100 45.78100 1.000 78.91472  ? 139 ARG A NH2  1 
ATOM   2180 H  H    . ARG A 1 139 ? 37.07800  -20.00600 43.28100 1.000 61.28000  ? 139 ARG A H    1 
ATOM   2181 H  HA   . ARG A 1 139 ? 39.54500  -19.41800 42.28400 1.000 65.35000  ? 139 ARG A HA   1 
ATOM   2182 H  HB2  . ARG A 1 139 ? 38.58000  -21.80400 43.50500 1.000 69.38000  ? 139 ARG A HB2  1 
ATOM   2183 H  HB3  . ARG A 1 139 ? 40.10300  -21.57800 43.12800 1.000 69.38000  ? 139 ARG A HB3  1 
ATOM   2184 H  HG2  . ARG A 1 139 ? 40.27100  -19.85300 44.70400 1.000 77.39000  ? 139 ARG A HG2  1 
ATOM   2185 H  HG3  . ARG A 1 139 ? 38.72500  -19.98300 45.03600 1.000 77.39000  ? 139 ARG A HG3  1 
ATOM   2186 H  HD2  . ARG A 1 139 ? 39.90200  -21.06500 46.69900 1.000 89.22000  ? 139 ARG A HD2  1 
ATOM   2187 H  HD3  . ARG A 1 139 ? 39.09600  -22.15700 45.88200 1.000 89.22000  ? 139 ARG A HD3  1 
ATOM   2188 H  HE   . ARG A 1 139 ? 41.56200  -21.96700 44.90100 1.000 91.59000  ? 139 ARG A HE   1 
ATOM   2189 H  HH11 . ARG A 1 139 ? 41.42000  -23.07200 48.18800 1.000 90.42000  ? 139 ARG A HH11 1 
ATOM   2190 H  HH12 . ARG A 1 139 ? 42.83200  -22.93000 47.62600 1.000 90.42000  ? 139 ARG A HH12 1 
ATOM   2191 H  HH21 . ARG A 1 139 ? 40.75400  -24.98900 45.95100 1.000 94.81000  ? 139 ARG A HH21 1 
ATOM   2192 H  HH22 . ARG A 1 139 ? 42.11100  -24.78100 45.28400 1.000 94.81000  ? 139 ARG A HH22 1 
ATOM   2193 N  N    . ALA A 1 140 ? 37.59800  -21.53600 40.70300 1.000 54.00121  ? 140 ALA A N    1 
ATOM   2194 C  CA   . ALA A 1 140 ? 37.46600  -22.11900 39.37300 1.000 53.40640  ? 140 ALA A CA   1 
ATOM   2195 C  C    . ALA A 1 140 ? 37.64600  -21.05800 38.29500 1.000 55.03291  ? 140 ALA A C    1 
ATOM   2196 O  O    . ALA A 1 140 ? 38.32400  -21.29100 37.28800 1.000 50.66134  ? 140 ALA A O    1 
ATOM   2197 C  CB   . ALA A 1 140 ? 36.10700  -22.80200 39.23200 1.000 51.89043  ? 140 ALA A CB   1 
ATOM   2198 H  H    . ALA A 1 140 ? 36.90500  -21.62300 41.20500 1.000 64.91000  ? 140 ALA A H    1 
ATOM   2199 H  HA   . ALA A 1 140 ? 38.15400  -22.79300 39.25400 1.000 64.20000  ? 140 ALA A HA   1 
ATOM   2200 H  HB1  . ALA A 1 140 ? 36.03500  -23.17900 38.34100 1.000 62.38000  ? 140 ALA A HB1  1 
ATOM   2201 H  HB2  . ALA A 1 140 ? 36.03700  -23.50600 39.89500 1.000 62.38000  ? 140 ALA A HB2  1 
ATOM   2202 H  HB3  . ALA A 1 140 ? 35.40700  -22.14600 39.37100 1.000 62.38000  ? 140 ALA A HB3  1 
ATOM   2203 N  N    . ARG A 1 141 ? 37.04900  -19.88000 38.49500 1.000 52.49577  ? 141 ARG A N    1 
ATOM   2204 C  CA   . ARG A 1 141 ? 37.20900  -18.79700 37.53100 1.000 53.31166  ? 141 ARG A CA   1 
ATOM   2205 C  C    . ARG A 1 141 ? 38.67200  -18.42100 37.35300 1.000 53.22217  ? 141 ARG A C    1 
ATOM   2206 O  O    . ARG A 1 141 ? 39.07200  -17.97600 36.27100 1.000 53.28534  ? 141 ARG A O    1 
ATOM   2207 C  CB   . ARG A 1 141 ? 36.39900  -17.57900 37.97700 1.000 52.28258  ? 141 ARG A CB   1 
ATOM   2208 C  CG   . ARG A 1 141 ? 35.01500  -17.50500 37.35800 1.000 61.85742  ? 141 ARG A CG   1 
ATOM   2209 C  CD   . ARG A 1 141 ? 34.22600  -16.30500 37.86200 1.000 68.24239  ? 141 ARG A CD   1 
ATOM   2210 N  NE   . ARG A 1 141 ? 32.88900  -16.26700 37.27700 1.000 81.65453  ? 141 ARG A NE   1 
ATOM   2211 C  CZ   . ARG A 1 141 ? 32.41800  -15.29100 36.50800 1.000 76.65130  ? 141 ARG A CZ   1 
ATOM   2212 N  NH1  . ARG A 1 141 ? 33.14500  -14.22600 36.21000 1.000 84.17062  ? 141 ARG A NH1  1 
ATOM   2213 N  NH2  . ARG A 1 141 ? 31.18200  -15.38800 36.02600 1.000 67.99763  ? 141 ARG A NH2  1 
ATOM   2214 H  H    . ARG A 1 141 ? 36.55500  -19.68700 39.17100 1.000 63.11000  ? 141 ARG A H    1 
ATOM   2215 H  HA   . ARG A 1 141 ? 36.86600  -19.08900 36.67200 1.000 64.08000  ? 141 ARG A HA   1 
ATOM   2216 H  HB2  . ARG A 1 141 ? 36.29100  -17.61200 38.94100 1.000 62.85000  ? 141 ARG A HB2  1 
ATOM   2217 H  HB3  . ARG A 1 141 ? 36.88000  -16.77500 37.72500 1.000 62.85000  ? 141 ARG A HB3  1 
ATOM   2218 H  HG2  . ARG A 1 141 ? 35.10000  -17.42800 36.39400 1.000 74.35000  ? 141 ARG A HG2  1 
ATOM   2219 H  HG3  . ARG A 1 141 ? 34.52000  -18.30900 37.58400 1.000 74.35000  ? 141 ARG A HG3  1 
ATOM   2220 H  HD2  . ARG A 1 141 ? 34.13700  -16.36100 38.82600 1.000 82.00000  ? 141 ARG A HD2  1 
ATOM   2221 H  HD3  . ARG A 1 141 ? 34.69100  -15.48900 37.61800 1.000 82.00000  ? 141 ARG A HD3  1 
ATOM   2222 H  HE   . ARG A 1 141 ? 32.36500  -16.92800 37.44300 1.000 98.10000  ? 141 ARG A HE   1 
ATOM   2223 H  HH11 . ARG A 1 141 ? 33.94500  -14.15200 36.51700 1.000 101.12000 ? 141 ARG A HH11 1 
ATOM   2224 H  HH12 . ARG A 1 141 ? 32.81700  -13.60700 35.71100 1.000 101.12000 ? 141 ARG A HH12 1 
ATOM   2225 H  HH21 . ARG A 1 141 ? 30.70000  -16.07600 36.21200 1.000 81.71000  ? 141 ARG A HH21 1 
ATOM   2226 H  HH22 . ARG A 1 141 ? 30.86500  -14.76300 35.52700 1.000 81.71000  ? 141 ARG A HH22 1 
ATOM   2227 N  N    . ALA A 1 142 ? 39.48300  -18.59400 38.39400 1.000 59.03339  ? 142 ALA A N    1 
ATOM   2228 C  CA   . ALA A 1 142 ? 40.90000  -18.26300 38.34000 1.000 57.51479  ? 142 ALA A CA   1 
ATOM   2229 C  C    . ALA A 1 142 ? 41.76000  -19.39400 37.79000 1.000 56.63574  ? 142 ALA A C    1 
ATOM   2230 O  O    . ALA A 1 142 ? 42.95800  -19.18500 37.56900 1.000 62.12587  ? 142 ALA A O    1 
ATOM   2231 C  CB   . ALA A 1 142 ? 41.40100  -17.88000 39.73700 1.000 58.73073  ? 142 ALA A CB   1 
ATOM   2232 H  H    . ALA A 1 142 ? 39.23000  -18.90500 39.15500 1.000 70.96000  ? 142 ALA A H    1 
ATOM   2233 H  HA   . ALA A 1 142 ? 41.01600  -17.49700 37.75700 1.000 69.13000  ? 142 ALA A HA   1 
ATOM   2234 H  HB1  . ALA A 1 142 ? 42.34200  -17.65100 39.68400 1.000 70.59000  ? 142 ALA A HB1  1 
ATOM   2235 H  HB2  . ALA A 1 142 ? 40.89300  -17.11800 40.05700 1.000 70.59000  ? 142 ALA A HB2  1 
ATOM   2236 H  HB3  . ALA A 1 142 ? 41.27800  -18.63400 40.33500 1.000 70.59000  ? 142 ALA A HB3  1 
ATOM   2237 N  N    . GLY A 1 143 ? 41.19300  -20.57800 37.57200 1.000 55.88038  ? 143 GLY A N    1 
ATOM   2238 C  CA   . GLY A 1 143 ? 41.92000  -21.70200 37.00800 1.000 59.47555  ? 143 GLY A CA   1 
ATOM   2239 C  C    . GLY A 1 143 ? 42.00400  -22.92700 37.89600 1.000 64.57353  ? 143 GLY A C    1 
ATOM   2240 O  O    . GLY A 1 143 ? 42.38000  -24.00100 37.40200 1.000 68.71877  ? 143 GLY A O    1 
ATOM   2241 H  H    . GLY A 1 143 ? 40.37000  -20.75400 37.74800 1.000 67.17000  ? 143 GLY A H    1 
ATOM   2242 H  HA2  . GLY A 1 143 ? 41.48600  -21.96700 36.18200 1.000 71.48000  ? 143 GLY A HA2  1 
ATOM   2243 H  HA3  . GLY A 1 143 ? 42.82600  -21.41800 36.81200 1.000 71.48000  ? 143 GLY A HA3  1 
ATOM   2244 N  N    . GLU A 1 144 ? 41.67900  -22.82700 39.18300 1.000 62.60751  ? 144 GLU A N    1 
ATOM   2245 C  CA   . GLU A 1 144 ? 41.75100  -23.95300 40.11200 1.000 61.16786  ? 144 GLU A CA   1 
ATOM   2246 C  C    . GLU A 1 144 ? 40.32400  -24.39800 40.42100 1.000 58.71493  ? 144 GLU A C    1 
ATOM   2247 O  O    . GLU A 1 144 ? 39.74700  -24.04900 41.45100 1.000 56.90682  ? 144 GLU A O    1 
ATOM   2248 C  CB   . GLU A 1 144 ? 42.51300  -23.56100 41.38100 1.000 69.17408  ? 144 GLU A CB   1 
ATOM   2249 C  CG   . GLU A 1 144 ? 43.91000  -23.02100 41.11800 1.000 74.58789  ? 144 GLU A CG   1 
ATOM   2250 C  CD   . GLU A 1 144 ? 43.95800  -21.50500 41.11100 1.000 83.13892  ? 144 GLU A CD   1 
ATOM   2251 O  OE1  . GLU A 1 144 ? 43.53700  -20.89100 42.11500 1.000 82.24934  ? 144 GLU A OE1  1 
ATOM   2252 O  OE2  . GLU A 1 144 ? 44.41700  -20.92900 40.10100 1.000 85.03388  ? 144 GLU A OE2  1 
ATOM   2253 H  H    . GLU A 1 144 ? 41.40600  -22.09900 39.55000 1.000 75.24000  ? 144 GLU A H    1 
ATOM   2254 H  HA   . GLU A 1 144 ? 42.22100  -24.68900 39.68900 1.000 73.51000  ? 144 GLU A HA   1 
ATOM   2255 H  HB2  . GLU A 1 144 ? 42.01200  -22.87200 41.84400 1.000 83.12000  ? 144 GLU A HB2  1 
ATOM   2256 H  HB3  . GLU A 1 144 ? 42.60000  -24.34500 41.94600 1.000 83.12000  ? 144 GLU A HB3  1 
ATOM   2257 H  HG2  . GLU A 1 144 ? 44.50800  -23.33700 41.81400 1.000 89.62000  ? 144 GLU A HG2  1 
ATOM   2258 H  HG3  . GLU A 1 144 ? 44.21400  -23.33600 40.25300 1.000 89.62000  ? 144 GLU A HG3  1 
ATOM   2259 N  N    . ALA A 1 145 ? 39.75600  -25.18800 39.51000 1.000 60.24407  ? 145 ALA A N    1 
ATOM   2260 C  CA   . ALA A 1 145 ? 38.37000  -25.62400 39.59700 1.000 52.62999  ? 145 ALA A CA   1 
ATOM   2261 C  C    . ALA A 1 145 ? 38.21900  -27.01300 40.20700 1.000 49.72701  ? 145 ALA A C    1 
ATOM   2262 O  O    . ALA A 1 145 ? 37.10900  -27.55500 40.21500 1.000 46.95826  ? 145 ALA A O    1 
ATOM   2263 C  CB   . ALA A 1 145 ? 37.73000  -25.60000 38.20800 1.000 56.22516  ? 145 ALA A CB   1 
ATOM   2264 H  H    . ALA A 1 145 ? 40.16700  -25.49100 38.81700 1.000 72.40000  ? 145 ALA A H    1 
ATOM   2265 H  HA   . ALA A 1 145 ? 37.89200  -25.00100 40.16700 1.000 63.27000  ? 145 ALA A HA   1 
ATOM   2266 H  HB1  . ALA A 1 145 ? 36.80400  -25.87900 38.28200 1.000 67.58000  ? 145 ALA A HB1  1 
ATOM   2267 H  HB2  . ALA A 1 145 ? 37.77700  -24.69800 37.85400 1.000 67.58000  ? 145 ALA A HB2  1 
ATOM   2268 H  HB3  . ALA A 1 145 ? 38.21300  -26.20800 37.62700 1.000 67.58000  ? 145 ALA A HB3  1 
ATOM   2269 N  N    . ALA A 1 146 ? 39.30300  -27.59800 40.72000 1.000 48.02944  ? 146 ALA A N    1 
ATOM   2270 C  CA   . ALA A 1 146 ? 39.22700  -28.95600 41.25200 1.000 51.35879  ? 146 ALA A CA   1 
ATOM   2271 C  C    . ALA A 1 146 ? 38.18300  -29.05600 42.35900 1.000 49.32170  ? 146 ALA A C    1 
ATOM   2272 O  O    . ALA A 1 146 ? 37.37600  -29.99300 42.38400 1.000 51.37721  ? 146 ALA A O    1 
ATOM   2273 C  CB   . ALA A 1 146 ? 40.59900  -29.39600 41.76300 1.000 53.66959  ? 146 ALA A CB   1 
ATOM   2274 H  H    . ALA A 1 146 ? 40.08200  -27.23600 40.77000 1.000 57.75000  ? 146 ALA A H    1 
ATOM   2275 H  HA   . ALA A 1 146 ? 38.96400  -29.55600 40.53700 1.000 61.74000  ? 146 ALA A HA   1 
ATOM   2276 H  HB1  . ALA A 1 146 ? 40.52800  -30.29100 42.12800 1.000 64.52000  ? 146 ALA A HB1  1 
ATOM   2277 H  HB2  . ALA A 1 146 ? 41.22800  -29.38800 41.02500 1.000 64.52000  ? 146 ALA A HB2  1 
ATOM   2278 H  HB3  . ALA A 1 146 ? 40.89100  -28.78000 42.45300 1.000 64.52000  ? 146 ALA A HB3  1 
ATOM   2279 N  N    . ASN A 1 147 ? 38.18200  -28.09600 43.28500 1.000 48.60320  ? 147 ASN A N    1 
ATOM   2280 C  CA   . ASN A 1 147 ? 37.21000  -28.13500 44.37300 1.000 50.77977  ? 147 ASN A CA   1 
ATOM   2281 C  C    . ASN A 1 147 ? 35.79900  -27.87500 43.86000 1.000 45.42650  ? 147 ASN A C    1 
ATOM   2282 O  O    . ASN A 1 147 ? 34.84700  -28.53900 44.28400 1.000 45.99236  ? 147 ASN A O    1 
ATOM   2283 C  CB   . ASN A 1 147 ? 37.58400  -27.11700 45.45000 1.000 50.39288  ? 147 ASN A CB   1 
ATOM   2284 C  CG   . ASN A 1 147 ? 38.79800  -27.53900 46.25400 1.000 55.35927  ? 147 ASN A CG   1 
ATOM   2285 O  OD1  . ASN A 1 147 ? 39.86300  -26.93100 46.15800 1.000 62.65751  ? 147 ASN A OD1  1 
ATOM   2286 N  ND2  . ASN A 1 147 ? 38.64200  -28.58700 47.05400 1.000 60.14142  ? 147 ASN A ND2  1 
ATOM   2287 H  H    . ASN A 1 147 ? 38.72100  -27.42700 43.30500 1.000 58.44000  ? 147 ASN A H    1 
ATOM   2288 H  HA   . ASN A 1 147 ? 37.22800  -29.01800 44.77500 1.000 61.05000  ? 147 ASN A HA   1 
ATOM   2289 H  HB2  . ASN A 1 147 ? 37.78400  -26.26700 45.02600 1.000 60.59000  ? 147 ASN A HB2  1 
ATOM   2290 H  HB3  . ASN A 1 147 ? 36.83800  -27.01500 46.06200 1.000 60.59000  ? 147 ASN A HB3  1 
ATOM   2291 H  HD21 . ASN A 1 147 ? 39.30100  -28.86500 47.53200 1.000 72.28000  ? 147 ASN A HD21 1 
ATOM   2292 H  HD22 . ASN A 1 147 ? 37.88200  -28.98700 47.09500 1.000 72.28000  ? 147 ASN A HD22 1 
ATOM   2293 N  N    . PHE A 1 148 ? 35.64500  -26.91300 42.94900 1.000 47.36621  ? 148 PHE A N    1 
ATOM   2294 C  CA   . PHE A 1 148 ? 34.32400  -26.62100 42.40300 1.000 47.30567  ? 148 PHE A CA   1 
ATOM   2295 C  C    . PHE A 1 148 ? 33.73500  -27.84700 41.71400 1.000 46.87930  ? 148 PHE A C    1 
ATOM   2296 O  O    . PHE A 1 148 ? 32.56100  -28.18000 41.91000 1.000 48.50845  ? 148 PHE A O    1 
ATOM   2297 C  CB   . PHE A 1 148 ? 34.40600  -25.44400 41.43000 1.000 46.90299  ? 148 PHE A CB   1 
ATOM   2298 C  CG   . PHE A 1 148 ? 33.06800  -24.95400 40.96000 1.000 44.90012  ? 148 PHE A CG   1 
ATOM   2299 C  CD1  . PHE A 1 148 ? 32.16900  -24.39300 41.85100 1.000 49.32433  ? 148 PHE A CD1  1 
ATOM   2300 C  CD2  . PHE A 1 148 ? 32.70600  -25.05500 39.63000 1.000 49.65859  ? 148 PHE A CD2  1 
ATOM   2301 C  CE1  . PHE A 1 148 ? 30.93500  -23.94200 41.42300 1.000 48.65583  ? 148 PHE A CE1  1 
ATOM   2302 C  CE2  . PHE A 1 148 ? 31.47700  -24.59900 39.19600 1.000 51.51670  ? 148 PHE A CE2  1 
ATOM   2303 C  CZ   . PHE A 1 148 ? 30.58800  -24.04700 40.09400 1.000 48.41896  ? 148 PHE A CZ   1 
ATOM   2304 H  H    . PHE A 1 148 ? 36.27900  -26.42300 42.63600 1.000 56.95000  ? 148 PHE A H    1 
ATOM   2305 H  HA   . PHE A 1 148 ? 33.73300  -26.36900 43.13000 1.000 56.88000  ? 148 PHE A HA   1 
ATOM   2306 H  HB2  . PHE A 1 148 ? 34.85400  -24.70600 41.87200 1.000 56.40000  ? 148 PHE A HB2  1 
ATOM   2307 H  HB3  . PHE A 1 148 ? 34.91200  -25.72000 40.64900 1.000 56.40000  ? 148 PHE A HB3  1 
ATOM   2308 H  HD1  . PHE A 1 148 ? 32.39900  -24.31800 42.74900 1.000 59.30000  ? 148 PHE A HD1  1 
ATOM   2309 H  HD2  . PHE A 1 148 ? 33.29800  -25.43400 39.02000 1.000 59.70000  ? 148 PHE A HD2  1 
ATOM   2310 H  HE1  . PHE A 1 148 ? 30.33900  -23.56700 42.03100 1.000 58.50000  ? 148 PHE A HE1  1 
ATOM   2311 H  HE2  . PHE A 1 148 ? 31.24800  -24.66400 38.29700 1.000 61.93000  ? 148 PHE A HE2  1 
ATOM   2312 H  HZ   . PHE A 1 148 ? 29.75700  -23.74800 39.80400 1.000 58.22000  ? 148 PHE A HZ   1 
ATOM   2313 N  N    . CYS A 1 149 ? 34.54100  -28.53700 40.90600 1.000 41.81291  ? 149 CYS A N    1 
ATOM   2314 C  CA   . CYS A 1 149 ? 34.03900  -29.72000 40.21400 1.000 47.69782  ? 149 CYS A CA   1 
ATOM   2315 C  C    . CYS A 1 149 ? 33.67700  -30.82100 41.20200 1.000 47.98470  ? 149 CYS A C    1 
ATOM   2316 O  O    . CYS A 1 149 ? 32.62300  -31.45600 41.07600 1.000 49.08483  ? 149 CYS A O    1 
ATOM   2317 C  CB   . CYS A 1 149 ? 35.07500  -30.21600 39.20800 1.000 50.74293  ? 149 CYS A CB   1 
ATOM   2318 S  SG   . CYS A 1 149 ? 35.35000  -29.07300 37.84500 1.000 53.15637  ? 149 CYS A SG   1 
ATOM   2319 H  H    . CYS A 1 149 ? 35.36400  -28.34500 40.74500 1.000 50.29000  ? 149 CYS A H    1 
ATOM   2320 H  HA   . CYS A 1 149 ? 33.23700  -29.48200 39.72400 1.000 57.35000  ? 149 CYS A HA   1 
ATOM   2321 H  HB2  . CYS A 1 149 ? 35.92100  -30.34300 39.66500 1.000 61.00000  ? 149 CYS A HB2  1 
ATOM   2322 H  HB3  . CYS A 1 149 ? 34.77100  -31.05700 38.83400 1.000 61.00000  ? 149 CYS A HB3  1 
ATOM   2323 H  HG   . CYS A 1 149 ? 36.17500  -29.53500 37.10700 1.000 63.90000  ? 149 CYS A HG   1 
ATOM   2324 N  N    . ALA A 1 150 ? 34.53600  -31.06400 42.19300 1.000 48.98745  ? 150 ALA A N    1 
ATOM   2325 C  CA   . ALA A 1 150 ? 34.21000  -32.05200 43.21500 1.000 46.34766  ? 150 ALA A CA   1 
ATOM   2326 C  C    . ALA A 1 150 ? 32.90100  -31.70500 43.91300 1.000 43.79472  ? 150 ALA A C    1 
ATOM   2327 O  O    . ALA A 1 150 ? 32.10600  -32.59500 44.23900 1.000 46.16080  ? 150 ALA A O    1 
ATOM   2328 C  CB   . ALA A 1 150 ? 35.35000  -32.15500 44.22700 1.000 47.72941  ? 150 ALA A CB   1 
ATOM   2329 H  H    . ALA A 1 150 ? 35.29700  -30.67700 42.29300 1.000 58.90000  ? 150 ALA A H    1 
ATOM   2330 H  HA   . ALA A 1 150 ? 34.10600  -32.92000 42.79400 1.000 55.73000  ? 150 ALA A HA   1 
ATOM   2331 H  HB1  . ALA A 1 150 ? 35.10300  -32.79100 44.91700 1.000 57.39000  ? 150 ALA A HB1  1 
ATOM   2332 H  HB2  . ALA A 1 150 ? 36.15100  -32.45700 43.77100 1.000 57.39000  ? 150 ALA A HB2  1 
ATOM   2333 H  HB3  . ALA A 1 150 ? 35.50200  -31.28200 44.62100 1.000 57.39000  ? 150 ALA A HB3  1 
ATOM   2334 N  N    . LEU A 1 151 ? 32.65200  -30.41300 44.13800 1.000 44.36585  ? 151 LEU A N    1 
ATOM   2335 C  CA   . LEU A 1 151 ? 31.41200  -30.00100 44.78900 1.000 41.96556  ? 151 LEU A CA   1 
ATOM   2336 C  C    . LEU A 1 151 ? 30.20900  -30.25800 43.88900 1.000 46.20291  ? 151 LEU A C    1 
ATOM   2337 O  O    . LEU A 1 151 ? 29.18000  -30.77000 44.34600 1.000 45.28964  ? 151 LEU A O    1 
ATOM   2338 C  CB   . LEU A 1 151 ? 31.49000  -28.52400 45.18100 1.000 46.56348  ? 151 LEU A CB   1 
ATOM   2339 C  CG   . LEU A 1 151 ? 32.27300  -28.21200 46.45900 1.000 45.97130  ? 151 LEU A CG   1 
ATOM   2340 C  CD1  . LEU A 1 151 ? 32.45200  -26.71200 46.63800 1.000 46.66875  ? 151 LEU A CD1  1 
ATOM   2341 C  CD2  . LEU A 1 151 ? 31.58400  -28.81100 47.67500 1.000 49.32170  ? 151 LEU A CD2  1 
ATOM   2342 H  H    . LEU A 1 151 ? 33.17700  -29.76600 43.92600 1.000 53.35000  ? 151 LEU A H    1 
ATOM   2343 H  HA   . LEU A 1 151 ? 31.29800  -30.52000 45.60000 1.000 50.47000  ? 151 LEU A HA   1 
ATOM   2344 H  HB2  . LEU A 1 151 ? 31.91700  -28.04000 44.45600 1.000 55.99000  ? 151 LEU A HB2  1 
ATOM   2345 H  HB3  . LEU A 1 151 ? 30.58600  -28.19700 45.31000 1.000 55.99000  ? 151 LEU A HB3  1 
ATOM   2346 H  HG   . LEU A 1 151 ? 33.15400  -28.61100 46.38300 1.000 55.28000  ? 151 LEU A HG   1 
ATOM   2347 H  HD11 . LEU A 1 151 ? 32.96500  -26.54900 47.44500 1.000 56.11000  ? 151 LEU A HD11 1 
ATOM   2348 H  HD12 . LEU A 1 151 ? 32.92200  -26.35600 45.86800 1.000 56.11000  ? 151 LEU A HD12 1 
ATOM   2349 H  HD13 . LEU A 1 151 ? 31.57800  -26.29700 46.71300 1.000 56.11000  ? 151 LEU A HD13 1 
ATOM   2350 H  HD21 . LEU A 1 151 ? 31.97800  -28.43600 48.47800 1.000 59.30000  ? 151 LEU A HD21 1 
ATOM   2351 H  HD22 . LEU A 1 151 ? 30.63900  -28.59700 47.63900 1.000 59.30000  ? 151 LEU A HD22 1 
ATOM   2352 H  HD23 . LEU A 1 151 ? 31.70600  -29.77300 47.66500 1.000 59.30000  ? 151 LEU A HD23 1 
ATOM   2353 N  N    . ILE A 1 152 ? 30.32200  -29.94900 42.59600 1.000 45.87655  ? 152 ILE A N    1 
ATOM   2354 C  CA   . ILE A 1 152 ? 29.20600  -30.16900 41.63100 1.000 46.24502  ? 152 ILE A CA   1 
ATOM   2355 C  C    . ILE A 1 152 ? 28.90500  -31.66400 41.61100 1.000 40.47327  ? 152 ILE A C    1 
ATOM   2356 O  O    . ILE A 1 152 ? 27.74700  -31.97800 41.54000 1.000 41.69184  ? 152 ILE A O    1 
ATOM   2357 C  CB   . ILE A 1 152 ? 29.49600  -29.64900 40.20900 1.000 49.17958  ? 152 ILE A CB   1 
ATOM   2358 C  CG1  . ILE A 1 152 ? 29.62800  -28.13100 40.14200 1.000 49.54278  ? 152 ILE A CG1  1 
ATOM   2359 C  CG2  . ILE A 1 152 ? 28.42900  -30.13400 39.23900 1.000 44.17372  ? 152 ILE A CG2  1 
ATOM   2360 C  CD1  . ILE A 1 152 ? 30.16600  -27.65900 38.82300 1.000 52.84844  ? 152 ILE A CD1  1 
ATOM   2361 H  H    . ILE A 1 152 ? 31.08000  -29.61700 42.21400 1.000 55.17000  ? 152 ILE A H    1 
ATOM   2362 H  HA   . ILE A 1 152 ? 28.41900  -29.70400 41.96500 1.000 55.61000  ? 152 ILE A HA   1 
ATOM   2363 H  HB   . ILE A 1 152 ? 30.35900  -30.03300 39.92200 1.000 59.13000  ? 152 ILE A HB   1 
ATOM   2364 H  HG12 . ILE A 1 152 ? 28.74600  -27.73100 40.28400 1.000 59.57000  ? 152 ILE A HG12 1 
ATOM   2365 H  HG13 . ILE A 1 152 ? 30.22100  -27.82300 40.86000 1.000 59.57000  ? 152 ILE A HG13 1 
ATOM   2366 H  HG21 . ILE A 1 152 ? 28.36600  -29.52000 38.48700 1.000 53.12000  ? 152 ILE A HG21 1 
ATOM   2367 H  HG22 . ILE A 1 152 ? 28.66000  -31.02000 38.91100 1.000 53.12000  ? 152 ILE A HG22 1 
ATOM   2368 H  HG23 . ILE A 1 152 ? 27.57100  -30.16900 39.69500 1.000 53.12000  ? 152 ILE A HG23 1 
ATOM   2369 H  HD11 . ILE A 1 152 ? 29.84100  -26.75900 38.64100 1.000 63.53000  ? 152 ILE A HD11 1 
ATOM   2370 H  HD12 . ILE A 1 152 ? 31.13500  -27.65700 38.85000 1.000 63.53000  ? 152 ILE A HD12 1 
ATOM   2371 H  HD13 . ILE A 1 152 ? 29.86500  -28.25800 38.11800 1.000 63.53000  ? 152 ILE A HD13 1 
ATOM   2372 N  N    . LEU A 1 153 ? 29.91400  -32.53200 41.58800 1.000 40.50749  ? 153 LEU A N    1 
ATOM   2373 C  CA   . LEU A 1 153 ? 29.70100  -33.97200 41.66000 1.000 40.17587  ? 153 LEU A CA   1 
ATOM   2374 C  C    . LEU A 1 153 ? 28.99600  -34.35800 42.95200 1.000 46.21607  ? 153 LEU A C    1 
ATOM   2375 O  O    . LEU A 1 153 ? 28.09100  -35.20100 42.94800 1.000 46.27923  ? 153 LEU A O    1 
ATOM   2376 C  CB   . LEU A 1 153 ? 31.04100  -34.69900 41.54300 1.000 42.45246  ? 153 LEU A CB   1 
ATOM   2377 C  CG   . LEU A 1 153 ? 31.66800  -34.67100 40.14700 1.000 47.48201  ? 153 LEU A CG   1 
ATOM   2378 C  CD1  . LEU A 1 153 ? 33.17400  -34.84600 40.22900 1.000 49.64279  ? 153 LEU A CD1  1 
ATOM   2379 C  CD2  . LEU A 1 153 ? 31.04700  -35.74600 39.27000 1.000 47.06354  ? 153 LEU A CD2  1 
ATOM   2380 H  H    . LEU A 1 153 ? 30.73100  -32.29900 41.45300 1.000 48.72000  ? 153 LEU A H    1 
ATOM   2381 H  HA   . LEU A 1 153 ? 29.14100  -34.24800 40.91800 1.000 48.32000  ? 153 LEU A HA   1 
ATOM   2382 H  HB2  . LEU A 1 153 ? 31.67000  -34.28400 42.15300 1.000 51.06000  ? 153 LEU A HB2  1 
ATOM   2383 H  HB3  . LEU A 1 153 ? 30.90700  -35.62800 41.78500 1.000 51.06000  ? 153 LEU A HB3  1 
ATOM   2384 H  HG   . LEU A 1 153 ? 31.49400  -33.80900 39.73900 1.000 57.09000  ? 153 LEU A HG   1 
ATOM   2385 H  HD11 . LEU A 1 153 ? 33.54300  -34.83700 39.33200 1.000 59.68000  ? 153 LEU A HD11 1 
ATOM   2386 H  HD12 . LEU A 1 153 ? 33.54900  -34.11800 40.74800 1.000 59.68000  ? 153 LEU A HD12 1 
ATOM   2387 H  HD13 . LEU A 1 153 ? 33.37100  -35.69400 40.65800 1.000 59.68000  ? 153 LEU A HD13 1 
ATOM   2388 H  HD21 . LEU A 1 153 ? 31.47300  -35.72800 38.39900 1.000 56.59000  ? 153 LEU A HD21 1 
ATOM   2389 H  HD22 . LEU A 1 153 ? 31.18300  -36.61100 39.68800 1.000 56.59000  ? 153 LEU A HD22 1 
ATOM   2390 H  HD23 . LEU A 1 153 ? 30.09800  -35.56900 39.17800 1.000 56.59000  ? 153 LEU A HD23 1 
ATOM   2391 N  N    . ALA A 1 154 ? 29.39200  -33.74400 44.07000 1.000 44.23688  ? 154 ALA A N    1 
ATOM   2392 C  CA   . ALA A 1 154 ? 28.79600  -34.09200 45.35600 1.000 45.51072  ? 154 ALA A CA   1 
ATOM   2393 C  C    . ALA A 1 154 ? 27.34600  -33.62900 45.43200 1.000 43.57628  ? 154 ALA A C    1 
ATOM   2394 O  O    . ALA A 1 154 ? 26.45600  -34.40400 45.80000 1.000 47.74520  ? 154 ALA A O    1 
ATOM   2395 C  CB   . ALA A 1 154 ? 29.61800  -33.48600 46.49500 1.000 46.77666  ? 154 ALA A CB   1 
ATOM   2396 H  H    . ALA A 1 154 ? 29.99400  -33.13100 44.10800 1.000 53.20000  ? 154 ALA A H    1 
ATOM   2397 H  HA   . ALA A 1 154 ? 28.80800  -35.05600 45.45600 1.000 54.73000  ? 154 ALA A HA   1 
ATOM   2398 H  HB1  . ALA A 1 154 ? 29.21100  -33.72700 47.34100 1.000 56.24000  ? 154 ALA A HB1  1 
ATOM   2399 H  HB2  . ALA A 1 154 ? 30.52200  -33.83500 46.45200 1.000 56.24000  ? 154 ALA A HB2  1 
ATOM   2400 H  HB3  . ALA A 1 154 ? 29.63100  -32.52100 46.39700 1.000 56.24000  ? 154 ALA A HB3  1 
ATOM   2401 N  N    . TYR A 1 155 ? 27.08600  -32.36600 45.08400 1.000 43.37099  ? 155 TYR A N    1 
ATOM   2402 C  CA   . TYR A 1 155 ? 25.71700  -31.86000 45.12600 1.000 46.22923  ? 155 TYR A CA   1 
ATOM   2403 C  C    . TYR A 1 155 ? 24.80200  -32.64900 44.19500 1.000 49.48751  ? 155 TYR A C    1 
ATOM   2404 O  O    . TYR A 1 155 ? 23.63400  -32.89300 44.52200 1.000 53.30376  ? 155 TYR A O    1 
ATOM   2405 C  CB   . TYR A 1 155 ? 25.69500  -30.37500 44.76000 1.000 44.92907  ? 155 TYR A CB   1 
ATOM   2406 C  CG   . TYR A 1 155 ? 26.17100  -29.46000 45.86600 1.000 46.39240  ? 155 TYR A CG   1 
ATOM   2407 C  CD1  . TYR A 1 155 ? 25.44400  -29.32100 47.04200 1.000 51.77726  ? 155 TYR A CD1  1 
ATOM   2408 C  CD2  . TYR A 1 155 ? 27.34800  -28.73400 45.73600 1.000 46.13448  ? 155 TYR A CD2  1 
ATOM   2409 C  CE1  . TYR A 1 155 ? 25.87400  -28.48400 48.05700 1.000 47.87153  ? 155 TYR A CE1  1 
ATOM   2410 C  CE2  . TYR A 1 155 ? 27.78800  -27.89600 46.74300 1.000 46.62138  ? 155 TYR A CE2  1 
ATOM   2411 C  CZ   . TYR A 1 155 ? 27.04800  -27.77500 47.90100 1.000 51.55092  ? 155 TYR A CZ   1 
ATOM   2412 O  OH   . TYR A 1 155 ? 27.48300  -26.94200 48.90400 1.000 50.54027  ? 155 TYR A OH   1 
ATOM   2413 H  H    . TYR A 1 155 ? 27.67400  -31.79500 44.82400 1.000 52.16000  ? 155 TYR A H    1 
ATOM   2414 H  HA   . TYR A 1 155 ? 25.38100  -31.95500 46.03100 1.000 55.59000  ? 155 TYR A HA   1 
ATOM   2415 H  HB2  . TYR A 1 155 ? 26.27300  -30.23600 43.99300 1.000 54.03000  ? 155 TYR A HB2  1 
ATOM   2416 H  HB3  . TYR A 1 155 ? 24.78500  -30.12300 44.53900 1.000 54.03000  ? 155 TYR A HB3  1 
ATOM   2417 H  HD1  . TYR A 1 155 ? 24.65300  -29.79900 47.14900 1.000 62.25000  ? 155 TYR A HD1  1 
ATOM   2418 H  HD2  . TYR A 1 155 ? 27.85000  -28.81400 44.95700 1.000 55.47000  ? 155 TYR A HD2  1 
ATOM   2419 H  HE1  . TYR A 1 155 ? 25.37700  -28.40000 48.83800 1.000 57.56000  ? 155 TYR A HE1  1 
ATOM   2420 H  HE2  . TYR A 1 155 ? 28.57800  -27.41600 46.64100 1.000 56.06000  ? 155 TYR A HE2  1 
ATOM   2421 H  HH   . TYR A 1 155 ? 26.92500  -26.93400 49.53300 1.000 60.76000  ? 155 TYR A HH   1 
ATOM   2422 N  N    . CYS A 1 156 ? 25.31100  -33.05700 43.03500 1.000 43.81052  ? 156 CYS A N    1 
ATOM   2423 C  CA   . CYS A 1 156 ? 24.50800  -33.75000 42.03500 1.000 51.30615  ? 156 CYS A CA   1 
ATOM   2424 C  C    . CYS A 1 156 ? 24.43400  -35.25400 42.26100 1.000 50.68239  ? 156 CYS A C    1 
ATOM   2425 O  O    . CYS A 1 156 ? 23.78200  -35.95000 41.47700 1.000 52.55893  ? 156 CYS A O    1 
ATOM   2426 C  CB   . CYS A 1 156 ? 25.06400  -33.47500 40.63400 1.000 43.73945  ? 156 CYS A CB   1 
ATOM   2427 S  SG   . CYS A 1 156 ? 24.82800  -31.77600 40.08200 1.000 51.00875  ? 156 CYS A SG   1 
ATOM   2428 H  H    . CYS A 1 156 ? 26.13100  -32.94200 42.80200 1.000 52.68000  ? 156 CYS A H    1 
ATOM   2429 H  HA   . CYS A 1 156 ? 23.60400  -33.40100 42.07600 1.000 61.68000  ? 156 CYS A HA   1 
ATOM   2430 H  HB2  . CYS A 1 156 ? 26.01700  -33.65700 40.63600 1.000 52.60000  ? 156 CYS A HB2  1 
ATOM   2431 H  HB3  . CYS A 1 156 ? 24.61700  -34.05800 40.00100 1.000 52.60000  ? 156 CYS A HB3  1 
ATOM   2432 H  HG   . CYS A 1 156 ? 25.23900  -31.66800 38.96000 1.000 61.32000  ? 156 CYS A HG   1 
ATOM   2433 N  N    . ASN A 1 157 ? 25.07900  -35.77000 43.30700 1.000 50.86136  ? 157 ASN A N    1 
ATOM   2434 C  CA   . ASN A 1 157 ? 25.07700  -37.20300 43.60000 1.000 49.61911  ? 157 ASN A CA   1 
ATOM   2435 C  C    . ASN A 1 157 ? 25.58300  -38.00300 42.40000 1.000 51.21404  ? 157 ASN A C    1 
ATOM   2436 O  O    . ASN A 1 157 ? 24.99400  -39.00300 41.98600 1.000 48.76901  ? 157 ASN A O    1 
ATOM   2437 C  CB   . ASN A 1 157 ? 23.68600  -37.67000 44.03200 1.000 50.27971  ? 157 ASN A CB   1 
ATOM   2438 C  CG   . ASN A 1 157 ? 23.48600  -37.57800 45.53300 1.000 61.11785  ? 157 ASN A CG   1 
ATOM   2439 O  OD1  . ASN A 1 157 ? 22.89300  -36.62300 46.03600 1.000 60.72570  ? 157 ASN A OD1  1 
ATOM   2440 N  ND2  . ASN A 1 157 ? 23.98900  -38.57000 46.25800 1.000 56.25411  ? 157 ASN A ND2  1 
ATOM   2441 H  H    . ASN A 1 157 ? 25.53100  -35.30300 43.87000 1.000 61.15000  ? 157 ASN A H    1 
ATOM   2442 H  HA   . ASN A 1 157 ? 25.68500  -37.37000 44.33700 1.000 59.66000  ? 157 ASN A HA   1 
ATOM   2443 H  HB2  . ASN A 1 157 ? 23.01700  -37.11300 43.60400 1.000 60.45000  ? 157 ASN A HB2  1 
ATOM   2444 H  HB3  . ASN A 1 157 ? 23.56600  -38.59500 43.76800 1.000 60.45000  ? 157 ASN A HB3  1 
ATOM   2445 H  HD21 . ASN A 1 157 ? 24.40200  -39.21800 45.87100 1.000 67.62000  ? 157 ASN A HD21 1 
ATOM   2446 H  HD22 . ASN A 1 157 ? 23.90200  -38.56500 47.11300 1.000 67.62000  ? 157 ASN A HD22 1 
ATOM   2447 N  N    . LYS A 1 158 ? 26.69700  -37.54400 41.84200 1.000 47.85574  ? 158 LYS A N    1 
ATOM   2448 C  CA   . LYS A 1 158 ? 27.38200  -38.22000 40.75300 1.000 54.00911  ? 158 LYS A CA   1 
ATOM   2449 C  C    . LYS A 1 158 ? 28.80700  -38.52900 41.18500 1.000 49.46119  ? 158 LYS A C    1 
ATOM   2450 O  O    . LYS A 1 158 ? 29.46200  -37.70000 41.82500 1.000 48.82164  ? 158 LYS A O    1 
ATOM   2451 C  CB   . LYS A 1 158 ? 27.39400  -37.35600 39.48500 1.000 51.87201  ? 158 LYS A CB   1 
ATOM   2452 C  CG   . LYS A 1 158 ? 26.05800  -37.29800 38.76100 1.000 49.67175  ? 158 LYS A CG   1 
ATOM   2453 C  CD   . LYS A 1 158 ? 25.80400  -38.57300 37.97300 1.000 62.63119  ? 158 LYS A CD   1 
ATOM   2454 C  CE   . LYS A 1 158 ? 24.42000  -38.58300 37.34600 1.000 62.54960  ? 158 LYS A CE   1 
ATOM   2455 N  NZ   . LYS A 1 158 ? 23.34300  -38.48300 38.36800 1.000 67.17121  ? 158 LYS A NZ   1 
ATOM   2456 H  H    . LYS A 1 158 ? 27.08700  -36.81800 42.08700 1.000 57.54000  ? 158 LYS A H    1 
ATOM   2457 H  HA   . LYS A 1 158 ? 26.93100  -39.05200 40.54200 1.000 64.92000  ? 158 LYS A HA   1 
ATOM   2458 H  HB2  . LYS A 1 158 ? 27.63700  -36.44900 39.73000 1.000 62.36000  ? 158 LYS A HB2  1 
ATOM   2459 H  HB3  . LYS A 1 158 ? 28.04800  -37.71900 38.86800 1.000 62.36000  ? 158 LYS A HB3  1 
ATOM   2460 H  HG2  . LYS A 1 158 ? 25.34400  -37.19100 39.40900 1.000 59.72000  ? 158 LYS A HG2  1 
ATOM   2461 H  HG3  . LYS A 1 158 ? 26.05900  -36.55100 38.14200 1.000 59.72000  ? 158 LYS A HG3  1 
ATOM   2462 H  HD2  . LYS A 1 158 ? 26.46000  -38.64700 37.26300 1.000 75.27000  ? 158 LYS A HD2  1 
ATOM   2463 H  HD3  . LYS A 1 158 ? 25.87300  -39.33600 38.56900 1.000 75.27000  ? 158 LYS A HD3  1 
ATOM   2464 H  HE2  . LYS A 1 158 ? 24.33700  -37.82600 36.74500 1.000 75.17000  ? 158 LYS A HE2  1 
ATOM   2465 H  HE3  . LYS A 1 158 ? 24.29700  -39.41100 36.85700 1.000 75.17000  ? 158 LYS A HE3  1 
ATOM   2466 H  HZ1  . LYS A 1 158 ? 22.54700  -38.57400 37.98100 1.000 80.72000  ? 158 LYS A HZ1  1 
ATOM   2467 H  HZ2  . LYS A 1 158 ? 23.44200  -39.12200 38.97900 1.000 80.72000  ? 158 LYS A HZ2  1 
ATOM   2468 H  HZ3  . LYS A 1 158 ? 23.37900  -37.69000 38.77100 1.000 80.72000  ? 158 LYS A HZ3  1 
ATOM   2469 N  N    . THR A 1 159 ? 29.27900  -39.72100 40.84300 1.000 49.97968  ? 159 THR A N    1 
ATOM   2470 C  CA   . THR A 1 159 ? 30.66400  -40.10200 41.06900 1.000 50.72713  ? 159 THR A CA   1 
ATOM   2471 C  C    . THR A 1 159 ? 31.48300  -39.85100 39.80800 1.000 59.60188  ? 159 THR A C    1 
ATOM   2472 O  O    . THR A 1 159 ? 30.96000  -39.82400 38.69100 1.000 58.35173  ? 159 THR A O    1 
ATOM   2473 C  CB   . THR A 1 159 ? 30.77700  -41.57400 41.47500 1.000 57.05947  ? 159 THR A CB   1 
ATOM   2474 O  OG1  . THR A 1 159 ? 30.19800  -42.40100 40.45900 1.000 59.76243  ? 159 THR A OG1  1 
ATOM   2475 C  CG2  . THR A 1 159 ? 30.07100  -41.82400 42.80100 1.000 55.55140  ? 159 THR A CG2  1 
ATOM   2476 H  H    . THR A 1 159 ? 28.80700  -40.33700 40.47300 1.000 60.09000  ? 159 THR A H    1 
ATOM   2477 H  HA   . THR A 1 159 ? 31.02700  -39.56700 41.79300 1.000 60.99000  ? 159 THR A HA   1 
ATOM   2478 H  HB   . THR A 1 159 ? 31.71300  -41.80600 41.58300 1.000 68.58000  ? 159 THR A HB   1 
ATOM   2479 H  HG1  . THR A 1 159 ? 30.24300  -43.20800 40.68600 1.000 71.83000  ? 159 THR A HG1  1 
ATOM   2480 H  HG21 . THR A 1 159 ? 30.16100  -42.75600 43.05400 1.000 66.78000  ? 159 THR A HG21 1 
ATOM   2481 H  HG22 . THR A 1 159 ? 30.46200  -41.27100 43.49500 1.000 66.78000  ? 159 THR A HG22 1 
ATOM   2482 H  HG23 . THR A 1 159 ? 29.12900  -41.60900 42.72100 1.000 66.78000  ? 159 THR A HG23 1 
ATOM   2483 N  N    . VAL A 1 160 ? 32.78700  -39.65900 40.00600 1.000 58.73336  ? 160 VAL A N    1 
ATOM   2484 C  CA   . VAL A 1 160 ? 33.69200  -39.48500 38.87900 1.000 53.77224  ? 160 VAL A CA   1 
ATOM   2485 C  C    . VAL A 1 160 ? 33.56200  -40.67900 37.94600 1.000 55.57508  ? 160 VAL A C    1 
ATOM   2486 O  O    . VAL A 1 160 ? 33.59700  -41.83700 38.38200 1.000 56.02251  ? 160 VAL A O    1 
ATOM   2487 C  CB   . VAL A 1 160 ? 35.13200  -39.30700 39.38000 1.000 53.16690  ? 160 VAL A CB   1 
ATOM   2488 C  CG1  . VAL A 1 160 ? 36.12400  -39.47700 38.23900 1.000 57.06210  ? 160 VAL A CG1  1 
ATOM   2489 C  CG2  . VAL A 1 160 ? 35.29000  -37.94600 40.03600 1.000 53.16427  ? 160 VAL A CG2  1 
ATOM   2490 H  H    . VAL A 1 160 ? 33.16800  -39.62700 40.77700 1.000 70.59000  ? 160 VAL A H    1 
ATOM   2491 H  HA   . VAL A 1 160 ? 33.44400  -38.68600 38.38600 1.000 64.64000  ? 160 VAL A HA   1 
ATOM   2492 H  HB   . VAL A 1 160 ? 35.32400  -39.99000 40.04100 1.000 63.91000  ? 160 VAL A HB   1 
ATOM   2493 H  HG11 . VAL A 1 160 ? 36.97800  -39.10100 38.50400 1.000 68.59000  ? 160 VAL A HG11 1 
ATOM   2494 H  HG12 . VAL A 1 160 ? 36.22400  -40.42200 38.04500 1.000 68.59000  ? 160 VAL A HG12 1 
ATOM   2495 H  HG13 . VAL A 1 160 ? 35.78700  -39.01300 37.45600 1.000 68.59000  ? 160 VAL A HG13 1 
ATOM   2496 H  HG21 . VAL A 1 160 ? 36.08900  -37.95100 40.58600 1.000 63.91000  ? 160 VAL A HG21 1 
ATOM   2497 H  HG22 . VAL A 1 160 ? 35.36800  -37.26900 39.34500 1.000 63.91000  ? 160 VAL A HG22 1 
ATOM   2498 H  HG23 . VAL A 1 160 ? 34.51100  -37.76800 40.58600 1.000 63.91000  ? 160 VAL A HG23 1 
ATOM   2499 N  N    . GLY A 1 161 ? 33.39900  -40.40200 36.65300 1.000 58.79916  ? 161 GLY A N    1 
ATOM   2500 C  CA   . GLY A 1 161 ? 33.21400  -41.43700 35.66100 1.000 59.28079  ? 161 GLY A CA   1 
ATOM   2501 C  C    . GLY A 1 161 ? 31.77200  -41.76900 35.34500 1.000 57.15948  ? 161 GLY A C    1 
ATOM   2502 O  O    . GLY A 1 161 ? 31.52100  -42.51200 34.38800 1.000 55.47244  ? 161 GLY A O    1 
ATOM   2503 H  H    . GLY A 1 161 ? 33.39300  -39.60600 36.32800 1.000 70.67000  ? 161 GLY A H    1 
ATOM   2504 H  HA2  . GLY A 1 161 ? 33.64000  -41.15600 34.83600 1.000 71.25000  ? 161 GLY A HA2  1 
ATOM   2505 H  HA3  . GLY A 1 161 ? 33.64200  -42.24900 35.97600 1.000 71.25000  ? 161 GLY A HA3  1 
ATOM   2506 N  N    . GLU A 1 162 ? 30.82000  -41.24400 36.11000 1.000 55.45402  ? 162 GLU A N    1 
ATOM   2507 C  CA   . GLU A 1 162 ? 29.41000  -41.51600 35.86900 1.000 60.86256  ? 162 GLU A CA   1 
ATOM   2508 C  C    . GLU A 1 162 ? 28.87000  -40.61000 34.77100 1.000 58.92022  ? 162 GLU A C    1 
ATOM   2509 O  O    . GLU A 1 162 ? 29.26700  -39.44700 34.65300 1.000 55.69352  ? 162 GLU A O    1 
ATOM   2510 C  CB   . GLU A 1 162 ? 28.60600  -41.31200 37.15400 1.000 59.97561  ? 162 GLU A CB   1 
ATOM   2511 C  CG   . GLU A 1 162 ? 27.26800  -42.03400 37.17300 1.000 66.24215  ? 162 GLU A CG   1 
ATOM   2512 C  CD   . GLU A 1 162 ? 26.62600  -42.04100 38.54900 1.000 69.18198  ? 162 GLU A CD   1 
ATOM   2513 O  OE1  . GLU A 1 162 ? 27.25900  -41.54700 39.50600 1.000 65.47101  ? 162 GLU A OE1  1 
ATOM   2514 O  OE2  . GLU A 1 162 ? 25.48800  -42.54000 38.67400 1.000 73.46144  ? 162 GLU A OE2  1 
ATOM   2515 H  H    . GLU A 1 162 ? 30.96700  -40.72300 36.77800 1.000 66.66000  ? 162 GLU A H    1 
ATOM   2516 H  HA   . GLU A 1 162 ? 29.30400  -42.43700 35.58300 1.000 73.15000  ? 162 GLU A HA   1 
ATOM   2517 H  HB2  . GLU A 1 162 ? 29.12800  -41.64100 37.90200 1.000 72.08000  ? 162 GLU A HB2  1 
ATOM   2518 H  HB3  . GLU A 1 162 ? 28.43000  -40.36500 37.26300 1.000 72.08000  ? 162 GLU A HB3  1 
ATOM   2519 H  HG2  . GLU A 1 162 ? 26.66000  -41.59100 36.56000 1.000 79.60000  ? 162 GLU A HG2  1 
ATOM   2520 H  HG3  . GLU A 1 162 ? 27.40100  -42.95500 36.89900 1.000 79.60000  ? 162 GLU A HG3  1 
ATOM   2521 N  N    . LEU A 1 163 ? 27.95400  -41.14800 33.96900 1.000 58.95444  ? 163 LEU A N    1 
ATOM   2522 C  CA   . LEU A 1 163 ? 27.31200  -40.35600 32.92800 1.000 57.72534  ? 163 LEU A CA   1 
ATOM   2523 C  C    . LEU A 1 163 ? 26.43200  -39.28400 33.55800 1.000 51.97728  ? 163 LEU A C    1 
ATOM   2524 O  O    . LEU A 1 163 ? 25.59500  -39.57900 34.41800 1.000 57.32266  ? 163 LEU A O    1 
ATOM   2525 C  CB   . LEU A 1 163 ? 26.48000  -41.25400 32.01300 1.000 61.79951  ? 163 LEU A CB   1 
ATOM   2526 C  CG   . LEU A 1 163 ? 25.65500  -40.54800 30.93200 1.000 73.26668  ? 163 LEU A CG   1 
ATOM   2527 C  CD1  . LEU A 1 163 ? 26.55400  -40.04900 29.81100 1.000 64.14453  ? 163 LEU A CD1  1 
ATOM   2528 C  CD2  . LEU A 1 163 ? 24.57000  -41.46700 30.38200 1.000 70.25053  ? 163 LEU A CD2  1 
ATOM   2529 H  H    . LEU A 1 163 ? 27.68900  -41.96500 34.00700 1.000 70.86000  ? 163 LEU A H    1 
ATOM   2530 H  HA   . LEU A 1 163 ? 27.99000  -39.92100 32.38800 1.000 69.38000  ? 163 LEU A HA   1 
ATOM   2531 H  HB2  . LEU A 1 163 ? 27.08400  -41.86300 31.55900 1.000 74.27000  ? 163 LEU A HB2  1 
ATOM   2532 H  HB3  . LEU A 1 163 ? 25.85900  -41.75400 32.56600 1.000 74.27000  ? 163 LEU A HB3  1 
ATOM   2533 H  HG   . LEU A 1 163 ? 25.21600  -39.78000 31.33100 1.000 88.03000  ? 163 LEU A HG   1 
ATOM   2534 H  HD11 . LEU A 1 163 ? 26.00900  -39.60500 29.14300 1.000 77.09000  ? 163 LEU A HD11 1 
ATOM   2535 H  HD12 . LEU A 1 163 ? 27.20100  -39.42600 30.17800 1.000 77.09000  ? 163 LEU A HD12 1 
ATOM   2536 H  HD13 . LEU A 1 163 ? 27.01300  -40.80500 29.41400 1.000 77.09000  ? 163 LEU A HD13 1 
ATOM   2537 H  HD21 . LEU A 1 163 ? 24.06700  -40.99100 29.70300 1.000 84.41000  ? 163 LEU A HD21 1 
ATOM   2538 H  HD22 . LEU A 1 163 ? 24.98800  -42.25200 29.99500 1.000 84.41000  ? 163 LEU A HD22 1 
ATOM   2539 H  HD23 . LEU A 1 163 ? 23.98100  -41.73000 31.10700 1.000 84.41000  ? 163 LEU A HD23 1 
ATOM   2540 N  N    . GLY A 1 164 ? 26.61700  -38.03900 33.12300 1.000 51.80358  ? 164 GLY A N    1 
ATOM   2541 C  CA   . GLY A 1 164 ? 25.84800  -36.92800 33.64600 1.000 51.17192  ? 164 GLY A CA   1 
ATOM   2542 C  C    . GLY A 1 164 ? 25.03800  -36.20200 32.59100 1.000 54.72761  ? 164 GLY A C    1 
ATOM   2543 O  O    . GLY A 1 164 ? 25.34100  -36.27900 31.39600 1.000 55.10661  ? 164 GLY A O    1 
ATOM   2544 H  H    . GLY A 1 164 ? 27.18900  -37.81600 32.52000 1.000 62.28000  ? 164 GLY A H    1 
ATOM   2545 H  HA2  . GLY A 1 164 ? 25.23500  -37.25800 34.32100 1.000 61.52000  ? 164 GLY A HA2  1 
ATOM   2546 H  HA3  . GLY A 1 164 ? 26.45300  -36.28900 34.05400 1.000 61.52000  ? 164 GLY A HA3  1 
ATOM   2547 N  N    . ASP A 1 165 ? 24.00300  -35.49100 33.03000 1.000 50.98506  ? 165 ASP A N    1 
ATOM   2548 C  CA   . ASP A 1 165 ? 23.14400  -34.70000 32.15800 1.000 50.08232  ? 165 ASP A CA   1 
ATOM   2549 C  C    . ASP A 1 165 ? 23.34700  -33.22400 32.46700 1.000 50.32972  ? 165 ASP A C    1 
ATOM   2550 O  O    . ASP A 1 165 ? 23.31600  -32.82100 33.63500 1.000 49.73228  ? 165 ASP A O    1 
ATOM   2551 C  CB   . ASP A 1 165 ? 21.67700  -35.09000 32.34900 1.000 51.29826  ? 165 ASP A CB   1 
ATOM   2552 C  CG   . ASP A 1 165 ? 20.76100  -34.43500 31.33500 1.000 56.61205  ? 165 ASP A CG   1 
ATOM   2553 O  OD1  . ASP A 1 165 ? 20.84800  -34.77800 30.13700 1.000 61.19944  ? 165 ASP A OD1  1 
ATOM   2554 O  OD2  . ASP A 1 165 ? 19.95400  -33.57200 31.74200 1.000 54.92501  ? 165 ASP A OD2  1 
ATOM   2555 H  H    . ASP A 1 165 ? 23.77200  -35.45000 33.85700 1.000 61.30000  ? 165 ASP A H    1 
ATOM   2556 H  HA   . ASP A 1 165 ? 23.38100  -34.85400 31.23000 1.000 60.21000  ? 165 ASP A HA   1 
ATOM   2557 H  HB2  . ASP A 1 165 ? 21.59000  -36.05100 32.25500 1.000 61.67000  ? 165 ASP A HB2  1 
ATOM   2558 H  HB3  . ASP A 1 165 ? 21.39000  -34.81500 33.23400 1.000 61.67000  ? 165 ASP A HB3  1 
ATOM   2559 N  N    . VAL A 1 166 ? 23.55000  -32.41900 31.42200 1.000 49.22432  ? 166 VAL A N    1 
ATOM   2560 C  CA   . VAL A 1 166 ? 23.80200  -30.99500 31.62700 1.000 47.50043  ? 166 VAL A CA   1 
ATOM   2561 C  C    . VAL A 1 166 ? 22.56200  -30.31100 32.19300 1.000 48.88481  ? 166 VAL A C    1 
ATOM   2562 O  O    . VAL A 1 166 ? 22.64400  -29.54800 33.16200 1.000 48.05313  ? 166 VAL A O    1 
ATOM   2563 C  CB   . VAL A 1 166 ? 24.26300  -30.33600 30.31500 1.000 46.20554  ? 166 VAL A CB   1 
ATOM   2564 C  CG1  . VAL A 1 166 ? 24.12200  -28.82200 30.39600 1.000 42.89988  ? 166 VAL A CG1  1 
ATOM   2565 C  CG2  . VAL A 1 166 ? 25.70200  -30.72200 30.00800 1.000 48.31106  ? 166 VAL A CG2  1 
ATOM   2566 H  H    . VAL A 1 166 ? 23.54700  -32.66900 30.59900 1.000 59.18000  ? 166 VAL A H    1 
ATOM   2567 H  HA   . VAL A 1 166 ? 24.51700  -30.90000 32.27500 1.000 57.12000  ? 166 VAL A HA   1 
ATOM   2568 H  HB   . VAL A 1 166 ? 23.70000  -30.65100 29.59100 1.000 55.56000  ? 166 VAL A HB   1 
ATOM   2569 H  HG11 . VAL A 1 166 ? 24.66000  -28.41700 29.69800 1.000 51.59000  ? 166 VAL A HG11 1 
ATOM   2570 H  HG12 . VAL A 1 166 ? 23.19000  -28.58500 30.27500 1.000 51.59000  ? 166 VAL A HG12 1 
ATOM   2571 H  HG13 . VAL A 1 166 ? 24.43000  -28.52300 31.26600 1.000 51.59000  ? 166 VAL A HG13 1 
ATOM   2572 H  HG21 . VAL A 1 166 ? 25.95500  -30.34400 29.15000 1.000 58.09000  ? 166 VAL A HG21 1 
ATOM   2573 H  HG22 . VAL A 1 166 ? 26.27900  -30.37300 30.70500 1.000 58.09000  ? 166 VAL A HG22 1 
ATOM   2574 H  HG23 . VAL A 1 166 ? 25.77000  -31.68900 29.97600 1.000 58.09000  ? 166 VAL A HG23 1 
ATOM   2575 N  N    . ARG A 1 167 ? 21.39500  -30.57600 31.60300 1.000 49.30065  ? 167 ARG A N    1 
ATOM   2576 C  CA   . ARG A 1 167 ? 20.16700  -29.95400 32.09000 1.000 48.70058  ? 167 ARG A CA   1 
ATOM   2577 C  C    . ARG A 1 167 ? 19.92200  -30.29000 33.55700 1.000 48.84007  ? 167 ARG A C    1 
ATOM   2578 O  O    . ARG A 1 167 ? 19.55200  -29.41500 34.35000 1.000 46.62927  ? 167 ARG A O    1 
ATOM   2579 C  CB   . ARG A 1 167 ? 18.98300  -30.39700 31.22800 1.000 45.24227  ? 167 ARG A CB   1 
ATOM   2580 C  CG   . ARG A 1 167 ? 17.68100  -29.66800 31.52200 1.000 44.77116  ? 167 ARG A CG   1 
ATOM   2581 C  CD   . ARG A 1 167 ? 16.51000  -30.63700 31.57900 1.000 49.80334  ? 167 ARG A CD   1 
ATOM   2582 N  NE   . ARG A 1 167 ? 16.42300  -31.31700 32.86700 1.000 52.40628  ? 167 ARG A NE   1 
ATOM   2583 C  CZ   . ARG A 1 167 ? 15.84700  -30.80800 33.94800 1.000 52.01939  ? 167 ARG A CZ   1 
ATOM   2584 N  NH1  . ARG A 1 167 ? 15.28200  -29.61200 33.93400 1.000 53.20112  ? 167 ARG A NH1  1 
ATOM   2585 N  NH2  . ARG A 1 167 ? 15.83700  -31.52000 35.07200 1.000 54.41442  ? 167 ARG A NH2  1 
ATOM   2586 H  H    . ARG A 1 167 ? 21.29000  -31.10300 30.93200 1.000 59.27000  ? 167 ARG A H    1 
ATOM   2587 H  HA   . ARG A 1 167 ? 20.24900  -28.99100 32.01500 1.000 58.55000  ? 167 ARG A HA   1 
ATOM   2588 H  HB2  . ARG A 1 167 ? 19.20300  -30.23900 30.29600 1.000 54.40000  ? 167 ARG A HB2  1 
ATOM   2589 H  HB3  . ARG A 1 167 ? 18.82900  -31.34300 31.37700 1.000 54.40000  ? 167 ARG A HB3  1 
ATOM   2590 H  HG2  . ARG A 1 167 ? 17.74900  -29.21900 32.37900 1.000 53.84000  ? 167 ARG A HG2  1 
ATOM   2591 H  HG3  . ARG A 1 167 ? 17.50800  -29.02000 30.82100 1.000 53.84000  ? 167 ARG A HG3  1 
ATOM   2592 H  HD2  . ARG A 1 167 ? 15.68400  -30.14800 31.43900 1.000 59.88000  ? 167 ARG A HD2  1 
ATOM   2593 H  HD3  . ARG A 1 167 ? 16.61900  -31.30900 30.88900 1.000 59.88000  ? 167 ARG A HD3  1 
ATOM   2594 H  HE   . ARG A 1 167 ? 16.76800  -32.10200 32.92900 1.000 63.00000  ? 167 ARG A HE   1 
ATOM   2595 H  HH11 . ARG A 1 167 ? 15.28300  -29.14400 33.21200 1.000 63.95000  ? 167 ARG A HH11 1 
ATOM   2596 H  HH12 . ARG A 1 167 ? 14.91400  -29.30100 34.64700 1.000 63.95000  ? 167 ARG A HH12 1 
ATOM   2597 H  HH21 . ARG A 1 167 ? 16.20000  -32.29900 35.09100 1.000 65.41000  ? 167 ARG A HH21 1 
ATOM   2598 H  HH22 . ARG A 1 167 ? 15.46600  -31.20100 35.78000 1.000 65.41000  ? 167 ARG A HH22 1 
ATOM   2599 N  N    . GLU A 1 168 ? 20.12200  -31.55300 33.93800 1.000 50.02705  ? 168 GLU A N    1 
ATOM   2600 C  CA   . GLU A 1 168 ? 19.98100  -31.93500 35.34000 1.000 44.82906  ? 168 GLU A CA   1 
ATOM   2601 C  C    . GLU A 1 168 ? 21.02700  -31.23400 36.19800 1.000 50.29287  ? 168 GLU A C    1 
ATOM   2602 O  O    . GLU A 1 168 ? 20.71600  -30.70200 37.27000 1.000 48.55319  ? 168 GLU A O    1 
ATOM   2603 C  CB   . GLU A 1 168 ? 20.09600  -33.45400 35.47900 1.000 49.95073  ? 168 GLU A CB   1 
ATOM   2604 C  CG   . GLU A 1 168 ? 19.70000  -33.99500 36.84600 1.000 52.20889  ? 168 GLU A CG   1 
ATOM   2605 C  CD   . GLU A 1 168 ? 18.19700  -34.03100 37.05200 1.000 56.78839  ? 168 GLU A CD   1 
ATOM   2606 O  OE1  . GLU A 1 168 ? 17.45500  -33.64900 36.12200 1.000 49.76123  ? 168 GLU A OE1  1 
ATOM   2607 O  OE2  . GLU A 1 168 ? 17.75900  -34.44400 38.14900 1.000 62.29957  ? 168 GLU A OE2  1 
ATOM   2608 H  H    . GLU A 1 168 ? 20.33700  -32.19800 33.41100 1.000 60.15000  ? 168 GLU A H    1 
ATOM   2609 H  HA   . GLU A 1 168 ? 19.10300  -31.66900 35.65500 1.000 53.91000  ? 168 GLU A HA   1 
ATOM   2610 H  HB2  . GLU A 1 168 ? 19.51600  -33.86800 34.82100 1.000 60.05000  ? 168 GLU A HB2  1 
ATOM   2611 H  HB3  . GLU A 1 168 ? 21.01700  -33.71000 35.31800 1.000 60.05000  ? 168 GLU A HB3  1 
ATOM   2612 H  HG2  . GLU A 1 168 ? 20.03700  -34.90100 36.93600 1.000 62.76000  ? 168 GLU A HG2  1 
ATOM   2613 H  HG3  . GLU A 1 168 ? 20.08400  -33.42900 37.53300 1.000 62.76000  ? 168 GLU A HG3  1 
ATOM   2614 N  N    . THR A 1 169 ? 22.27900  -31.21900 35.73300 1.000 49.94020  ? 169 THR A N    1 
ATOM   2615 C  CA   . THR A 1 169 ? 23.35100  -30.57800 36.48800 1.000 48.31895  ? 169 THR A CA   1 
ATOM   2616 C  C    . THR A 1 169 ? 23.05200  -29.10100 36.72300 1.000 51.04559  ? 169 THR A C    1 
ATOM   2617 O  O    . THR A 1 169 ? 23.14300  -28.61000 37.85500 1.000 48.75848  ? 169 THR A O    1 
ATOM   2618 C  CB   . THR A 1 169 ? 24.67900  -30.74800 35.74600 1.000 49.16379  ? 169 THR A CB   1 
ATOM   2619 O  OG1  . THR A 1 169 ? 24.99100  -32.14300 35.63300 1.000 47.53991  ? 169 THR A OG1  1 
ATOM   2620 C  CG2  . THR A 1 169 ? 25.80900  -30.03400 36.47600 1.000 47.61624  ? 169 THR A CG2  1 
ATOM   2621 H  H    . THR A 1 169 ? 22.52900  -31.57000 34.98900 1.000 60.04000  ? 169 THR A H    1 
ATOM   2622 H  HA   . THR A 1 169 ? 23.42800  -31.00900 37.35300 1.000 58.10000  ? 169 THR A HA   1 
ATOM   2623 H  HB   . THR A 1 169 ? 24.60100  -30.36000 34.86000 1.000 59.11000  ? 169 THR A HB   1 
ATOM   2624 H  HG1  . THR A 1 169 ? 24.38800  -32.53900 35.20200 1.000 57.16000  ? 169 THR A HG1  1 
ATOM   2625 H  HG21 . THR A 1 169 ? 26.66400  -30.40000 36.20300 1.000 57.25000  ? 169 THR A HG21 1 
ATOM   2626 H  HG22 . THR A 1 169 ? 25.79100  -29.08700 36.26800 1.000 57.25000  ? 169 THR A HG22 1 
ATOM   2627 H  HG23 . THR A 1 169 ? 25.70800  -30.14800 37.43400 1.000 57.25000  ? 169 THR A HG23 1 
ATOM   2628 N  N    . MET A 1 170 ? 22.69700  -28.37300 35.66000 1.000 48.52950  ? 170 MET A N    1 
ATOM   2629 C  CA   . MET A 1 170 ? 22.36300  -26.96100 35.81900 1.000 48.04787  ? 170 MET A CA   1 
ATOM   2630 C  C    . MET A 1 170 ? 21.19800  -26.77400 36.78200 1.000 46.01341  ? 170 MET A C    1 
ATOM   2631 O  O    . MET A 1 170 ? 21.14400  -25.77400 37.50600 1.000 46.62138  ? 170 MET A O    1 
ATOM   2632 C  CB   . MET A 1 170 ? 22.02300  -26.33800 34.46400 1.000 47.25567  ? 170 MET A CB   1 
ATOM   2633 C  CG   . MET A 1 170 ? 23.13100  -26.41400 33.41700 1.000 53.36166  ? 170 MET A CG   1 
ATOM   2634 S  SD   . MET A 1 170 ? 24.70600  -25.71000 33.93500 1.000 47.73204  ? 170 MET A SD   1 
ATOM   2635 C  CE   . MET A 1 170 ? 24.21600  -24.04400 34.36900 1.000 51.36405  ? 170 MET A CE   1 
ATOM   2636 H  H    . MET A 1 170 ? 22.64400  -28.66800 34.85400 1.000 58.35000  ? 170 MET A H    1 
ATOM   2637 H  HA   . MET A 1 170 ? 23.14300  -26.50200 36.16800 1.000 57.77000  ? 170 MET A HA   1 
ATOM   2638 H  HB2  . MET A 1 170 ? 21.24900  -26.79700 34.10200 1.000 56.82000  ? 170 MET A HB2  1 
ATOM   2639 H  HB3  . MET A 1 170 ? 21.81700  -25.40000 34.60200 1.000 56.82000  ? 170 MET A HB3  1 
ATOM   2640 H  HG2  . MET A 1 170 ? 23.28500  -27.34600 33.19900 1.000 64.15000  ? 170 MET A HG2  1 
ATOM   2641 H  HG3  . MET A 1 170 ? 22.84200  -25.93200 32.62700 1.000 64.15000  ? 170 MET A HG3  1 
ATOM   2642 H  HE1  . MET A 1 170 ? 25.00500  -23.53800 34.62100 1.000 61.75000  ? 170 MET A HE1  1 
ATOM   2643 H  HE2  . MET A 1 170 ? 23.78900  -23.63100 33.60300 1.000 61.75000  ? 170 MET A HE2  1 
ATOM   2644 H  HE3  . MET A 1 170 ? 23.59600  -24.08100 35.11400 1.000 61.75000  ? 170 MET A HE3  1 
ATOM   2645 N  N    . SER A 1 171 ? 20.25600  -27.72100 36.79800 1.000 46.53189  ? 171 SER A N    1 
ATOM   2646 C  CA   . SER A 1 171 ? 19.12400  -27.62800 37.71300 1.000 50.50606  ? 171 SER A CA   1 
ATOM   2647 C  C    . SER A 1 171 ? 19.59700  -27.60300 39.16000 1.000 49.50594  ? 171 SER A C    1 
ATOM   2648 O  O    . SER A 1 171 ? 19.18500  -26.74200 39.94500 1.000 47.85311  ? 171 SER A O    1 
ATOM   2649 C  CB   . SER A 1 171 ? 18.16700  -28.79800 37.48500 1.000 51.23772  ? 171 SER A CB   1 
ATOM   2650 O  OG   . SER A 1 171 ? 16.85000  -28.45900 37.88200 1.000 61.90742  ? 171 SER A OG   1 
ATOM   2651 H  H    . SER A 1 171 ? 20.25100  -28.41700 36.29400 1.000 55.95000  ? 171 SER A H    1 
ATOM   2652 H  HA   . SER A 1 171 ? 18.64300  -26.80500 37.53400 1.000 60.72000  ? 171 SER A HA   1 
ATOM   2653 H  HB2  . SER A 1 171 ? 18.16400  -29.02300 36.54100 1.000 61.59000  ? 171 SER A HB2  1 
ATOM   2654 H  HB3  . SER A 1 171 ? 18.46900  -29.55800 38.00600 1.000 61.59000  ? 171 SER A HB3  1 
ATOM   2655 H  HG   . SER A 1 171 ? 16.33300  -29.10700 37.74400 1.000 74.40000  ? 171 SER A HG   1 
ATOM   2656 N  N    . TYR A 1 172 ? 20.46700  -28.54400 39.53100 1.000 50.19549  ? 172 TYR A N    1 
ATOM   2657 C  CA   . TYR A 1 172 ? 20.98500  -28.57700 40.89400 1.000 54.85658  ? 172 TYR A CA   1 
ATOM   2658 C  C    . TYR A 1 172 ? 21.70600  -27.28000 41.23500 1.000 49.02693  ? 172 TYR A C    1 
ATOM   2659 O  O    . TYR A 1 172 ? 21.49600  -26.69900 42.30500 1.000 52.77738  ? 172 TYR A O    1 
ATOM   2660 C  CB   . TYR A 1 172 ? 21.92300  -29.77100 41.06900 1.000 51.68514  ? 172 TYR A CB   1 
ATOM   2661 C  CG   . TYR A 1 172 ? 21.21700  -31.06800 41.39100 1.000 56.99104  ? 172 TYR A CG   1 
ATOM   2662 C  CD1  . TYR A 1 172 ? 20.78900  -31.91800 40.38000 1.000 57.20423  ? 172 TYR A CD1  1 
ATOM   2663 C  CD2  . TYR A 1 172 ? 20.98100  -31.44300 42.70600 1.000 57.94905  ? 172 TYR A CD2  1 
ATOM   2664 C  CE1  . TYR A 1 172 ? 20.14400  -33.10600 40.67000 1.000 60.31513  ? 172 TYR A CE1  1 
ATOM   2665 C  CE2  . TYR A 1 172 ? 20.33700  -32.62800 43.00700 1.000 61.74688  ? 172 TYR A CE2  1 
ATOM   2666 C  CZ   . TYR A 1 172 ? 19.92000  -33.45600 41.98500 1.000 58.07012  ? 172 TYR A CZ   1 
ATOM   2667 O  OH   . TYR A 1 172 ? 19.27800  -34.63600 42.27800 1.000 63.53657  ? 172 TYR A OH   1 
ATOM   2668 H  H    . TYR A 1 172 ? 20.76900  -29.16500 39.01800 1.000 60.35000  ? 172 TYR A H    1 
ATOM   2669 H  HA   . TYR A 1 172 ? 20.24200  -28.68300 41.50900 1.000 65.94000  ? 172 TYR A HA   1 
ATOM   2670 H  HB2  . TYR A 1 172 ? 22.41700  -29.90100 40.24400 1.000 62.13000  ? 172 TYR A HB2  1 
ATOM   2671 H  HB3  . TYR A 1 172 ? 22.53600  -29.58100 41.79600 1.000 62.13000  ? 172 TYR A HB3  1 
ATOM   2672 H  HD1  . TYR A 1 172 ? 20.93800  -31.68500 39.49200 1.000 68.76000  ? 172 TYR A HD1  1 
ATOM   2673 H  HD2  . TYR A 1 172 ? 21.26200  -30.88800 43.39700 1.000 69.66000  ? 172 TYR A HD2  1 
ATOM   2674 H  HE1  . TYR A 1 172 ? 19.86200  -33.66600 39.98300 1.000 72.49000  ? 172 TYR A HE1  1 
ATOM   2675 H  HE2  . TYR A 1 172 ? 20.18600  -32.86700 43.89300 1.000 74.21000  ? 172 TYR A HE2  1 
ATOM   2676 H  HH   . TYR A 1 172 ? 19.21600  -34.73100 43.11000 1.000 76.36000  ? 172 TYR A HH   1 
ATOM   2677 N  N    . LEU A 1 173 ? 22.56200  -26.80500 40.32800 1.000 48.01892  ? 173 LEU A N    1 
ATOM   2678 C  CA   . LEU A 1 173 ? 23.33300  -25.59900 40.60600 1.000 51.49038  ? 173 LEU A CA   1 
ATOM   2679 C  C    . LEU A 1 173 ? 22.42400  -24.38400 40.74200 1.000 50.88505  ? 173 LEU A C    1 
ATOM   2680 O  O    . LEU A 1 173 ? 22.60900  -23.56100 41.64700 1.000 48.52424  ? 173 LEU A O    1 
ATOM   2681 C  CB   . LEU A 1 173 ? 24.37200  -25.38000 39.50600 1.000 47.55570  ? 173 LEU A CB   1 
ATOM   2682 C  CG   . LEU A 1 173 ? 25.44600  -26.46600 39.38300 1.000 49.03746  ? 173 LEU A CG   1 
ATOM   2683 C  CD1  . LEU A 1 173 ? 26.46700  -26.09500 38.31700 1.000 47.97154  ? 173 LEU A CD1  1 
ATOM   2684 C  CD2  . LEU A 1 173 ? 26.14200  -26.71400 40.71500 1.000 52.47208  ? 173 LEU A CD2  1 
ATOM   2685 H  H    . LEU A 1 173 ? 22.71000  -27.15800 39.55700 1.000 57.74000  ? 173 LEU A H    1 
ATOM   2686 H  HA   . LEU A 1 173 ? 23.80500  -25.71200 41.44500 1.000 61.90000  ? 173 LEU A HA   1 
ATOM   2687 H  HB2  . LEU A 1 173 ? 23.90800  -25.33400 38.65500 1.000 57.18000  ? 173 LEU A HB2  1 
ATOM   2688 H  HB3  . LEU A 1 173 ? 24.82700  -24.54200 39.68100 1.000 57.18000  ? 173 LEU A HB3  1 
ATOM   2689 H  HG   . LEU A 1 173 ? 25.01100  -27.29100 39.11800 1.000 58.96000  ? 173 LEU A HG   1 
ATOM   2690 H  HD11 . LEU A 1 173 ? 27.13900  -26.79300 38.26700 1.000 57.68000  ? 173 LEU A HD11 1 
ATOM   2691 H  HD12 . LEU A 1 173 ? 26.01500  -26.00900 37.46300 1.000 57.68000  ? 173 LEU A HD12 1 
ATOM   2692 H  HD13 . LEU A 1 173 ? 26.88300  -25.25200 38.55800 1.000 57.68000  ? 173 LEU A HD13 1 
ATOM   2693 H  HD21 . LEU A 1 173 ? 26.85700  -27.35600 40.58200 1.000 63.08000  ? 173 LEU A HD21 1 
ATOM   2694 H  HD22 . LEU A 1 173 ? 26.50500  -25.87700 41.04200 1.000 63.08000  ? 173 LEU A HD22 1 
ATOM   2695 H  HD23 . LEU A 1 173 ? 25.49600  -27.06500 41.34800 1.000 63.08000  ? 173 LEU A HD23 1 
ATOM   2696 N  N    . PHE A 1 174 ? 21.43300  -24.25200 39.85500 1.000 49.24801  ? 174 PHE A N    1 
ATOM   2697 C  CA   . PHE A 1 174 ? 20.48400  -23.15200 39.98200 1.000 47.61360  ? 174 PHE A CA   1 
ATOM   2698 C  C    . PHE A 1 174 ? 19.71900  -23.23400 41.29600 1.000 52.06414  ? 174 PHE A C    1 
ATOM   2699 O  O    . PHE A 1 174 ? 19.36100  -22.20100 41.87400 1.000 49.76386  ? 174 PHE A O    1 
ATOM   2700 C  CB   . PHE A 1 174 ? 19.50800  -23.15300 38.80500 1.000 47.59518  ? 174 PHE A CB   1 
ATOM   2701 C  CG   . PHE A 1 174 ? 20.14300  -22.82400 37.47300 1.000 47.09249  ? 174 PHE A CG   1 
ATOM   2702 C  CD1  . PHE A 1 174 ? 21.44900  -22.36800 37.39100 1.000 46.66349  ? 174 PHE A CD1  1 
ATOM   2703 C  CD2  . PHE A 1 174 ? 19.42000  -22.97300 36.30200 1.000 46.44767  ? 174 PHE A CD2  1 
ATOM   2704 C  CE1  . PHE A 1 174 ? 22.01800  -22.06800 36.16800 1.000 48.57688  ? 174 PHE A CE1  1 
ATOM   2705 C  CE2  . PHE A 1 174 ? 19.98500  -22.67400 35.07700 1.000 51.72725  ? 174 PHE A CE2  1 
ATOM   2706 C  CZ   . PHE A 1 174 ? 21.28600  -22.22300 35.01000 1.000 49.25854  ? 174 PHE A CZ   1 
ATOM   2707 H  H    . PHE A 1 174 ? 21.29400  -24.77600 39.18800 1.000 59.21000  ? 174 PHE A H    1 
ATOM   2708 H  HA   . PHE A 1 174 ? 20.97300  -22.31500 39.96200 1.000 57.25000  ? 174 PHE A HA   1 
ATOM   2709 H  HB2  . PHE A 1 174 ? 19.11100  -24.03500 38.73100 1.000 57.23000  ? 174 PHE A HB2  1 
ATOM   2710 H  HB3  . PHE A 1 174 ? 18.81900  -22.49200 38.97300 1.000 57.23000  ? 174 PHE A HB3  1 
ATOM   2711 H  HD1  . PHE A 1 174 ? 21.94800  -22.26300 38.16800 1.000 56.11000  ? 174 PHE A HD1  1 
ATOM   2712 H  HD2  . PHE A 1 174 ? 18.54200  -23.27800 36.34100 1.000 55.85000  ? 174 PHE A HD2  1 
ATOM   2713 H  HE1  . PHE A 1 174 ? 22.89500  -21.76200 36.12600 1.000 58.41000  ? 174 PHE A HE1  1 
ATOM   2714 H  HE2  . PHE A 1 174 ? 19.48800  -22.77800 34.29800 1.000 62.19000  ? 174 PHE A HE2  1 
ATOM   2715 H  HZ   . PHE A 1 174 ? 21.66800  -22.02300 34.18600 1.000 59.22000  ? 174 PHE A HZ   1 
ATOM   2716 N  N    . GLN A 1 175 ? 19.45900  -24.45000 41.78400 1.000 46.58716  ? 175 GLN A N    1 
ATOM   2717 C  CA   . GLN A 1 175 ? 18.76900  -24.59800 43.06000 1.000 53.55642  ? 175 GLN A CA   1 
ATOM   2718 C  C    . GLN A 1 175 ? 19.59300  -24.03000 44.20600 1.000 52.01413  ? 175 GLN A C    1 
ATOM   2719 O  O    . GLN A 1 175 ? 19.03300  -23.61300 45.22500 1.000 53.59327  ? 175 GLN A O    1 
ATOM   2720 C  CB   . GLN A 1 175 ? 18.45300  -26.07000 43.31600 1.000 58.54123  ? 175 GLN A CB   1 
ATOM   2721 C  CG   . GLN A 1 175 ? 17.45100  -26.65900 42.34300 1.000 64.25770  ? 175 GLN A CG   1 
ATOM   2722 C  CD   . GLN A 1 175 ? 16.03600  -26.50600 42.83500 1.000 66.75537  ? 175 GLN A CD   1 
ATOM   2723 O  OE1  . GLN A 1 175 ? 15.77800  -25.73100 43.75300 1.000 66.92381  ? 175 GLN A OE1  1 
ATOM   2724 N  NE2  . GLN A 1 175 ? 15.10900  -27.24300 42.23300 1.000 73.72726  ? 175 GLN A NE2  1 
ATOM   2725 H  H    . GLN A 1 175 ? 19.66800  -25.19100 41.40000 1.000 56.02000  ? 175 GLN A H    1 
ATOM   2726 H  HA   . GLN A 1 175 ? 17.93100  -24.11200 43.02100 1.000 64.38000  ? 175 GLN A HA   1 
ATOM   2727 H  HB2  . GLN A 1 175 ? 19.27300  -26.58300 43.24200 1.000 70.36000  ? 175 GLN A HB2  1 
ATOM   2728 H  HB3  . GLN A 1 175 ? 18.08500  -26.15900 44.20900 1.000 70.36000  ? 175 GLN A HB3  1 
ATOM   2729 H  HG2  . GLN A 1 175 ? 17.52700  -26.20400 41.49100 1.000 77.22000  ? 175 GLN A HG2  1 
ATOM   2730 H  HG3  . GLN A 1 175 ? 17.63300  -27.60600 42.23100 1.000 77.22000  ? 175 GLN A HG3  1 
ATOM   2731 H  HE21 . GLN A 1 175 ? 15.33100  -27.77500 41.59500 1.000 88.58000  ? 175 GLN A HE21 1 
ATOM   2732 H  HE22 . GLN A 1 175 ? 14.28700  -27.18800 42.48100 1.000 88.58000  ? 175 GLN A HE22 1 
ATOM   2733 N  N    . HIS A 1 176 ? 20.91800  -24.00700 44.06000 1.000 48.56109  ? 176 HIS A N    1 
ATOM   2734 C  CA   . HIS A 1 176 ? 21.81400  -23.45800 45.06700 1.000 55.47507  ? 176 HIS A CA   1 
ATOM   2735 C  C    . HIS A 1 176 ? 22.26100  -22.04000 44.72800 1.000 52.47208  ? 176 HIS A C    1 
ATOM   2736 O  O    . HIS A 1 176 ? 23.31300  -21.59800 45.20100 1.000 50.78767  ? 176 HIS A O    1 
ATOM   2737 C  CB   . HIS A 1 176 ? 23.02800  -24.37100 45.23800 1.000 50.54290  ? 176 HIS A CB   1 
ATOM   2738 C  CG   . HIS A 1 176 ? 22.70900  -25.67200 45.90600 1.000 56.95683  ? 176 HIS A CG   1 
ATOM   2739 N  ND1  . HIS A 1 176 ? 22.66300  -25.81200 47.27600 1.000 59.59662  ? 176 HIS A ND1  1 
ATOM   2740 C  CD2  . HIS A 1 176 ? 22.41200  -26.88900 45.39300 1.000 55.42770  ? 176 HIS A CD2  1 
ATOM   2741 C  CE1  . HIS A 1 176 ? 22.35600  -27.06100 47.57900 1.000 62.79437  ? 176 HIS A CE1  1 
ATOM   2742 N  NE2  . HIS A 1 176 ? 22.19900  -27.73500 46.45400 1.000 60.83361  ? 176 HIS A NE2  1 
ATOM   2743 H  H    . HIS A 1 176 ? 21.32800  -24.31200 43.36800 1.000 58.39000  ? 176 HIS A H    1 
ATOM   2744 H  HA   . HIS A 1 176 ? 21.34400  -23.42300 45.91400 1.000 66.69000  ? 176 HIS A HA   1 
ATOM   2745 H  HB2  . HIS A 1 176 ? 23.39600  -24.56900 44.36300 1.000 60.77000  ? 176 HIS A HB2  1 
ATOM   2746 H  HB3  . HIS A 1 176 ? 23.68900  -23.91300 45.78000 1.000 60.77000  ? 176 HIS A HB3  1 
ATOM   2747 H  HD1  . HIS A 1 176 ? 22.81000  -25.18500 47.84600 1.000 71.63000  ? 176 HIS A HD1  1 
ATOM   2748 H  HD2  . HIS A 1 176 ? 22.36200  -27.11100 44.49100 1.000 66.63000  ? 176 HIS A HD2  1 
ATOM   2749 H  HE1  . HIS A 1 176 ? 22.26500  -27.40700 48.43700 1.000 75.47000  ? 176 HIS A HE1  1 
ATOM   2750 N  N    . ALA A 1 177 ? 21.48100  -21.32300 43.92300 1.000 51.04559  ? 177 ALA A N    1 
ATOM   2751 C  CA   . ALA A 1 177 ? 21.80600  -19.96500 43.51700 1.000 50.25076  ? 177 ALA A CA   1 
ATOM   2752 C  C    . ALA A 1 177 ? 20.64200  -19.04300 43.85000 1.000 53.45904  ? 177 ALA A C    1 
ATOM   2753 O  O    . ALA A 1 177 ? 19.51600  -19.48800 44.09000 1.000 52.11941  ? 177 ALA A O    1 
ATOM   2754 C  CB   . ALA A 1 177 ? 22.12400  -19.88800 42.01800 1.000 48.07155  ? 177 ALA A CB   1 
ATOM   2755 H  H    . ALA A 1 177 ? 20.74200  -21.61100 43.59100 1.000 61.37000  ? 177 ALA A H    1 
ATOM   2756 H  HA   . ALA A 1 177 ? 22.58400  -19.66000 44.00900 1.000 60.42000  ? 177 ALA A HA   1 
ATOM   2757 H  HB1  . ALA A 1 177 ? 22.33300  -18.96900 41.78700 1.000 57.80000  ? 177 ALA A HB1  1 
ATOM   2758 H  HB2  . ALA A 1 177 ? 22.88500  -20.45800 41.82700 1.000 57.80000  ? 177 ALA A HB2  1 
ATOM   2759 H  HB3  . ALA A 1 177 ? 21.35100  -20.18800 41.51500 1.000 57.80000  ? 177 ALA A HB3  1 
ATOM   2760 N  N    . ASN A 1 178 ? 20.93000  -17.74400 43.86200 1.000 48.51898  ? 178 ASN A N    1 
ATOM   2761 C  CA   . ASN A 1 178 ? 19.92600  -16.72600 44.16200 1.000 52.13520  ? 178 ASN A CA   1 
ATOM   2762 C  C    . ASN A 1 178 ? 19.22000  -16.36000 42.86300 1.000 54.52233  ? 178 ASN A C    1 
ATOM   2763 O  O    . ASN A 1 178 ? 19.73800  -15.58500 42.05400 1.000 52.87476  ? 178 ASN A O    1 
ATOM   2764 C  CB   . ASN A 1 178 ? 20.56400  -15.50600 44.81500 1.000 50.66660  ? 178 ASN A CB   1 
ATOM   2765 C  CG   . ASN A 1 178 ? 19.54300  -14.44200 45.18300 1.000 57.51479  ? 178 ASN A CG   1 
ATOM   2766 O  OD1  . ASN A 1 178 ? 18.33600  -14.64300 45.03700 1.000 55.96987  ? 178 ASN A OD1  1 
ATOM   2767 N  ND2  . ASN A 1 178 ? 20.02500  -13.30200 45.66600 1.000 62.47854  ? 178 ASN A ND2  1 
ATOM   2768 H  H    . ASN A 1 178 ? 21.71100  -17.42200 43.69800 1.000 58.34000  ? 178 ASN A H    1 
ATOM   2769 H  HA   . ASN A 1 178 ? 19.27200  -17.09300 44.77700 1.000 62.68000  ? 178 ASN A HA   1 
ATOM   2770 H  HB2  . ASN A 1 178 ? 21.01700  -15.78200 45.62700 1.000 60.91000  ? 178 ASN A HB2  1 
ATOM   2771 H  HB3  . ASN A 1 178 ? 21.20000  -15.11200 44.19800 1.000 60.91000  ? 178 ASN A HB3  1 
ATOM   2772 H  HD21 . ASN A 1 178 ? 20.87400  -13.19800 45.75500 1.000 75.09000  ? 178 ASN A HD21 1 
ATOM   2773 H  HD22 . ASN A 1 178 ? 19.48800  -12.66800 45.88900 1.000 75.09000  ? 178 ASN A HD22 1 
ATOM   2774 N  N    . LEU A 1 179 ? 18.03300  -16.93200 42.66100 1.000 55.26189  ? 179 LEU A N    1 
ATOM   2775 C  CA   . LEU A 1 179 ? 17.18200  -16.61000 41.52300 1.000 55.54877  ? 179 LEU A CA   1 
ATOM   2776 C  C    . LEU A 1 179 ? 15.81500  -16.11100 41.97600 1.000 58.72020  ? 179 LEU A C    1 
ATOM   2777 O  O    . LEU A 1 179 ? 14.84100  -16.20500 41.22200 1.000 58.77810  ? 179 LEU A O    1 
ATOM   2778 C  CB   . LEU A 1 179 ? 17.03200  -17.82800 40.61100 1.000 54.86974  ? 179 LEU A CB   1 
ATOM   2779 C  CG   . LEU A 1 179 ? 18.34000  -18.39100 40.05000 1.000 59.04919  ? 179 LEU A CG   1 
ATOM   2780 C  CD1  . LEU A 1 179 ? 18.10400  -19.72700 39.35900 1.000 55.00660  ? 179 LEU A CD1  1 
ATOM   2781 C  CD2  . LEU A 1 179 ? 18.98500  -17.39500 39.09300 1.000 57.40162  ? 179 LEU A CD2  1 
ATOM   2782 H  H    . LEU A 1 179 ? 17.69300  -17.52400 43.18400 1.000 66.43000  ? 179 LEU A H    1 
ATOM   2783 H  HA   . LEU A 1 179 ? 17.59900  -15.90400 41.00500 1.000 66.77000  ? 179 LEU A HA   1 
ATOM   2784 H  HB2  . LEU A 1 179 ? 16.60500  -18.53700 41.11700 1.000 65.96000  ? 179 LEU A HB2  1 
ATOM   2785 H  HB3  . LEU A 1 179 ? 16.47700  -17.57800 39.85600 1.000 65.96000  ? 179 LEU A HB3  1 
ATOM   2786 H  HG   . LEU A 1 179 ? 18.95500  -18.54300 40.78500 1.000 70.97000  ? 179 LEU A HG   1 
ATOM   2787 H  HD11 . LEU A 1 179 ? 17.49300  -19.59500 38.61700 1.000 66.12000  ? 179 LEU A HD11 1 
ATOM   2788 H  HD12 . LEU A 1 179 ? 18.95200  -20.06700 39.03200 1.000 66.12000  ? 179 LEU A HD12 1 
ATOM   2789 H  HD13 . LEU A 1 179 ? 17.72200  -20.34900 39.99600 1.000 66.12000  ? 179 LEU A HD13 1 
ATOM   2790 H  HD21 . LEU A 1 179 ? 19.69600  -17.84000 38.60700 1.000 69.00000  ? 179 LEU A HD21 1 
ATOM   2791 H  HD22 . LEU A 1 179 ? 18.31200  -17.07200 38.47400 1.000 69.00000  ? 179 LEU A HD22 1 
ATOM   2792 H  HD23 . LEU A 1 179 ? 19.34600  -16.65400 39.60500 1.000 69.00000  ? 179 LEU A HD23 1 
ATOM   2793 N  N    . ASP A 1 180 ? 15.73100  -15.57300 43.19700 1.000 59.16499  ? 180 ASP A N    1 
ATOM   2794 C  CA   . ASP A 1 180 ? 14.45200  -15.14900 43.75500 1.000 66.09477  ? 180 ASP A CA   1 
ATOM   2795 C  C    . ASP A 1 180 ? 13.82900  -13.99300 42.98500 1.000 66.08161  ? 180 ASP A C    1 
ATOM   2796 O  O    . ASP A 1 180 ? 12.62100  -13.76300 43.11100 1.000 71.81387  ? 180 ASP A O    1 
ATOM   2797 C  CB   . ASP A 1 180 ? 14.63400  -14.75100 45.22300 1.000 66.54219  ? 180 ASP A CB   1 
ATOM   2798 C  CG   . ASP A 1 180 ? 15.15500  -15.89100 46.07700 1.000 68.43452  ? 180 ASP A CG   1 
ATOM   2799 O  OD1  . ASP A 1 180 ? 15.14700  -17.04500 45.59900 1.000 73.43512  ? 180 ASP A OD1  1 
ATOM   2800 O  OD2  . ASP A 1 180 ? 15.57200  -15.63400 47.22600 1.000 70.83218  ? 180 ASP A OD2  1 
ATOM   2801 H  H    . ASP A 1 180 ? 16.40100  -15.44400 43.71900 1.000 71.11000  ? 180 ASP A H    1 
ATOM   2802 H  HA   . ASP A 1 180 ? 13.83700  -15.89800 43.71300 1.000 79.43000  ? 180 ASP A HA   1 
ATOM   2803 H  HB2  . ASP A 1 180 ? 15.27100  -14.02000 45.27600 1.000 79.96000  ? 180 ASP A HB2  1 
ATOM   2804 H  HB3  . ASP A 1 180 ? 13.77800  -14.47200 45.58400 1.000 79.96000  ? 180 ASP A HB3  1 
ATOM   2805 N  N    . SER A 1 181 ? 14.61500  -13.25900 42.20200 1.000 61.67582  ? 181 SER A N    1 
ATOM   2806 C  CA   . SER A 1 181 ? 14.09900  -12.15200 41.40800 1.000 66.36059  ? 181 SER A CA   1 
ATOM   2807 C  C    . SER A 1 181 ? 13.57800  -12.59200 40.04500 1.000 64.30245  ? 181 SER A C    1 
ATOM   2808 O  O    . SER A 1 181 ? 13.15900  -11.74000 39.25400 1.000 63.88398  ? 181 SER A O    1 
ATOM   2809 C  CB   . SER A 1 181 ? 15.18700  -11.08800 41.21700 1.000 61.52053  ? 181 SER A CB   1 
ATOM   2810 O  OG   . SER A 1 181 ? 15.10900  -10.09200 42.22200 1.000 78.83050  ? 181 SER A OG   1 
ATOM   2811 H  H    . SER A 1 181 ? 15.46100  -13.38500 42.11400 1.000 74.12000  ? 181 SER A H    1 
ATOM   2812 H  HA   . SER A 1 181 ? 13.36200  -11.74500 41.89100 1.000 79.75000  ? 181 SER A HA   1 
ATOM   2813 H  HB2  . SER A 1 181 ? 16.05600  -11.51600 41.26400 1.000 73.94000  ? 181 SER A HB2  1 
ATOM   2814 H  HB3  . SER A 1 181 ? 15.06900  -10.67000 40.35000 1.000 73.94000  ? 181 SER A HB3  1 
ATOM   2815 H  HG   . SER A 1 181 ? 15.71600  -9.52200  42.10800 1.000 94.71000  ? 181 SER A HG   1 
ATOM   2816 N  N    . CYS A 1 182 ? 13.58600  -13.88900 39.75200 1.000 57.30687  ? 182 CYS A N    1 
ATOM   2817 C  CA   . CYS A 1 182 ? 13.19600  -14.38300 38.43800 1.000 54.65392  ? 182 CYS A CA   1 
ATOM   2818 C  C    . CYS A 1 182 ? 11.71200  -14.72500 38.42300 1.000 55.15661  ? 182 CYS A C    1 
ATOM   2819 O  O    . CYS A 1 182 ? 11.21200  -15.39800 39.32900 1.000 56.96736  ? 182 CYS A O    1 
ATOM   2820 C  CB   . CYS A 1 182 ? 14.02800  -15.60700 38.05700 1.000 50.99032  ? 182 CYS A CB   1 
ATOM   2821 S  SG   . CYS A 1 182 ? 15.78700  -15.25300 37.84400 1.000 54.29072  ? 182 CYS A SG   1 
ATOM   2822 H  H    . CYS A 1 182 ? 13.81500  -14.50800 40.30300 1.000 68.88000  ? 182 CYS A H    1 
ATOM   2823 H  HA   . CYS A 1 182 ? 13.35000  -13.69000 37.77700 1.000 65.70000  ? 182 CYS A HA   1 
ATOM   2824 H  HB2  . CYS A 1 182 ? 13.94300  -16.27200 38.75700 1.000 61.30000  ? 182 CYS A HB2  1 
ATOM   2825 H  HB3  . CYS A 1 182 ? 13.69400  -15.96300 37.21900 1.000 61.30000  ? 182 CYS A HB3  1 
ATOM   2826 H  HG   . CYS A 1 182 ? 16.35900  -16.26900 37.56000 1.000 65.26000  ? 182 CYS A HG   1 
ATOM   2827 N  N    . LYS A 1 183 ? 11.01500  -14.26000 37.38600 1.000 58.35437  ? 183 LYS A N    1 
ATOM   2828 C  CA   . LYS A 1 183 ? 9.58300   -14.47700 37.24400 1.000 57.10685  ? 183 LYS A CA   1 
ATOM   2829 C  C    . LYS A 1 183 ? 9.26100   -14.80700 35.79600 1.000 58.03327  ? 183 LYS A C    1 
ATOM   2830 O  O    . LYS A 1 183 ? 9.87800   -14.26600 34.87400 1.000 58.79916  ? 183 LYS A O    1 
ATOM   2831 C  CB   . LYS A 1 183 ? 8.78400   -13.24400 37.68700 1.000 57.56743  ? 183 LYS A CB   1 
ATOM   2832 C  CG   . LYS A 1 183 ? 7.29100   -13.49400 37.84400 1.000 65.06570  ? 183 LYS A CG   1 
ATOM   2833 C  CD   . LYS A 1 183 ? 6.52800   -12.19000 38.03800 1.000 74.77212  ? 183 LYS A CD   1 
ATOM   2834 C  CE   . LYS A 1 183 ? 5.02300   -12.41000 37.99400 1.000 77.03292  ? 183 LYS A CE   1 
ATOM   2835 N  NZ   . LYS A 1 183 ? 4.29600   -11.51900 38.94100 1.000 87.72368  ? 183 LYS A NZ   1 
ATOM   2836 H  H    . LYS A 1 183 ? 11.35900  -13.80700 36.74200 1.000 70.14000  ? 183 LYS A H    1 
ATOM   2837 H  HA   . LYS A 1 183 ? 9.31500   -15.23000 37.79400 1.000 68.64000  ? 183 LYS A HA   1 
ATOM   2838 H  HB2  . LYS A 1 183 ? 9.12500   -12.94500 38.54400 1.000 69.19000  ? 183 LYS A HB2  1 
ATOM   2839 H  HB3  . LYS A 1 183 ? 8.89800   -12.54600 37.02300 1.000 69.19000  ? 183 LYS A HB3  1 
ATOM   2840 H  HG2  . LYS A 1 183 ? 6.95200   -13.93000 37.04700 1.000 78.19000  ? 183 LYS A HG2  1 
ATOM   2841 H  HG3  . LYS A 1 183 ? 7.13900   -14.05500 38.62000 1.000 78.19000  ? 183 LYS A HG3  1 
ATOM   2842 H  HD2  . LYS A 1 183 ? 6.75500   -11.81000 38.90200 1.000 89.84000  ? 183 LYS A HD2  1 
ATOM   2843 H  HD3  . LYS A 1 183 ? 6.76500   -11.57000 37.33100 1.000 89.84000  ? 183 LYS A HD3  1 
ATOM   2844 H  HE2  . LYS A 1 183 ? 4.70100   -12.22700 37.09800 1.000 92.55000  ? 183 LYS A HE2  1 
ATOM   2845 H  HE3  . LYS A 1 183 ? 4.82900   -13.33000 38.23400 1.000 92.55000  ? 183 LYS A HE3  1 
ATOM   2846 H  HZ1  . LYS A 1 183 ? 3.42100   -11.67300 38.89300 1.000 105.38000 ? 183 LYS A HZ1  1 
ATOM   2847 H  HZ2  . LYS A 1 183 ? 4.57000   -11.67200 39.77400 1.000 105.38000 ? 183 LYS A HZ2  1 
ATOM   2848 H  HZ3  . LYS A 1 183 ? 4.45100   -10.66700 38.73800 1.000 105.38000 ? 183 LYS A HZ3  1 
ATOM   2849 N  N    . ARG A 1 184 ? 8.28700   -15.69300 35.60600 1.000 58.47806  ? 184 ARG A N    1 
ATOM   2850 C  CA   . ARG A 1 184 ? 7.84300   -16.10300 34.28300 1.000 59.65189  ? 184 ARG A CA   1 
ATOM   2851 C  C    . ARG A 1 184 ? 6.33400   -16.28100 34.30300 1.000 61.13891  ? 184 ARG A C    1 
ATOM   2852 O  O    . ARG A 1 184 ? 5.78100   -16.84100 35.25400 1.000 58.33331  ? 184 ARG A O    1 
ATOM   2853 C  CB   . ARG A 1 184 ? 8.51800   -17.40800 33.84400 1.000 57.85694  ? 184 ARG A CB   1 
ATOM   2854 C  CG   . ARG A 1 184 ? 7.77900   -18.14900 32.74000 1.000 58.60176  ? 184 ARG A CG   1 
ATOM   2855 C  CD   . ARG A 1 184 ? 8.62700   -19.27000 32.16800 1.000 58.34910  ? 184 ARG A CD   1 
ATOM   2856 N  NE   . ARG A 1 184 ? 9.77400   -18.76500 31.42500 1.000 53.54326  ? 184 ARG A NE   1 
ATOM   2857 C  CZ   . ARG A 1 184 ? 10.79600  -19.51000 31.02600 1.000 55.55666  ? 184 ARG A CZ   1 
ATOM   2858 N  NH1  . ARG A 1 184 ? 10.84100  -20.80900 31.27400 1.000 56.28306  ? 184 ARG A NH1  1 
ATOM   2859 N  NH2  . ARG A 1 184 ? 11.79600  -18.93900 30.36100 1.000 58.48596  ? 184 ARG A NH2  1 
ATOM   2860 H  H    . ARG A 1 184 ? 7.86000   -16.07900 36.24500 1.000 70.29000  ? 184 ARG A H    1 
ATOM   2861 H  HA   . ARG A 1 184 ? 8.06400   -15.41700 33.63400 1.000 71.70000  ? 184 ARG A HA   1 
ATOM   2862 H  HB2  . ARG A 1 184 ? 9.40700   -17.20300 33.51700 1.000 69.54000  ? 184 ARG A HB2  1 
ATOM   2863 H  HB3  . ARG A 1 184 ? 8.57500   -18.00100 34.61000 1.000 69.54000  ? 184 ARG A HB3  1 
ATOM   2864 H  HG2  . ARG A 1 184 ? 6.96400   -18.53500 33.10000 1.000 70.44000  ? 184 ARG A HG2  1 
ATOM   2865 H  HG3  . ARG A 1 184 ? 7.56500   -17.53100 32.02400 1.000 70.44000  ? 184 ARG A HG3  1 
ATOM   2866 H  HD2  . ARG A 1 184 ? 8.95600   -19.82400 32.89300 1.000 70.13000  ? 184 ARG A HD2  1 
ATOM   2867 H  HD3  . ARG A 1 184 ? 8.08600   -19.80300 31.56400 1.000 70.13000  ? 184 ARG A HD3  1 
ATOM   2868 H  HE   . ARG A 1 184 ? 9.79000   -17.92700 31.23200 1.000 64.37000  ? 184 ARG A HE   1 
ATOM   2869 H  HH11 . ARG A 1 184 ? 10.19900  -21.18800 31.70300 1.000 67.65000  ? 184 ARG A HH11 1 
ATOM   2870 H  HH12 . ARG A 1 184 ? 11.51300  -21.27500 31.00600 1.000 67.65000  ? 184 ARG A HH12 1 
ATOM   2871 H  HH21 . ARG A 1 184 ? 11.77500  -18.09600 30.19400 1.000 70.30000  ? 184 ARG A HH21 1 
ATOM   2872 H  HH22 . ARG A 1 184 ? 12.46300  -19.41300 30.09700 1.000 70.30000  ? 184 ARG A HH22 1 
ATOM   2873 N  N    . VAL A 1 185 ? 5.67300   -15.80400 33.25200 1.000 61.77583  ? 185 VAL A N    1 
ATOM   2874 C  CA   . VAL A 1 185 ? 4.23100   -15.93600 33.09700 1.000 64.25244  ? 185 VAL A CA   1 
ATOM   2875 C  C    . VAL A 1 185 ? 3.95900   -16.60900 31.76100 1.000 65.20782  ? 185 VAL A C    1 
ATOM   2876 O  O    . VAL A 1 185 ? 4.42900   -16.14100 30.71700 1.000 66.40533  ? 185 VAL A O    1 
ATOM   2877 C  CB   . VAL A 1 185 ? 3.52000   -14.57300 33.17900 1.000 66.16320  ? 185 VAL A CB   1 
ATOM   2878 C  CG1  . VAL A 1 185 ? 2.01200   -14.75400 33.06800 1.000 68.93984  ? 185 VAL A CG1  1 
ATOM   2879 C  CG2  . VAL A 1 185 ? 3.88400   -13.86200 34.47500 1.000 68.20028  ? 185 VAL A CG2  1 
ATOM   2880 H  H    . VAL A 1 185 ? 6.05000   -15.38900 32.60100 1.000 74.25000  ? 185 VAL A H    1 
ATOM   2881 H  HA   . VAL A 1 185 ? 3.88200   -16.50200 33.80300 1.000 77.22000  ? 185 VAL A HA   1 
ATOM   2882 H  HB   . VAL A 1 185 ? 3.81100   -14.01900 32.43800 1.000 79.51000  ? 185 VAL A HB   1 
ATOM   2883 H  HG11 . VAL A 1 185 ? 1.58000   -13.89900 33.21800 1.000 82.84000  ? 185 VAL A HG11 1 
ATOM   2884 H  HG12 . VAL A 1 185 ? 1.79800   -15.08200 32.18100 1.000 82.84000  ? 185 VAL A HG12 1 
ATOM   2885 H  HG13 . VAL A 1 185 ? 1.72100   -15.39400 33.73700 1.000 82.84000  ? 185 VAL A HG13 1 
ATOM   2886 H  HG21 . VAL A 1 185 ? 3.37400   -13.04000 34.53800 1.000 81.95000  ? 185 VAL A HG21 1 
ATOM   2887 H  HG22 . VAL A 1 185 ? 3.67100   -14.44200 35.22300 1.000 81.95000  ? 185 VAL A HG22 1 
ATOM   2888 H  HG23 . VAL A 1 185 ? 4.83300   -13.66400 34.47000 1.000 81.95000  ? 185 VAL A HG23 1 
ATOM   2889 N  N    . LEU A 1 186 ? 3.20600   -17.70600 31.79600 1.000 67.92657  ? 186 LEU A N    1 
ATOM   2890 C  CA   . LEU A 1 186 ? 2.83500   -18.44900 30.60400 1.000 71.11905  ? 186 LEU A CA   1 
ATOM   2891 C  C    . LEU A 1 186 ? 1.32500   -18.41200 30.42400 1.000 71.74808  ? 186 LEU A C    1 
ATOM   2892 O  O    . LEU A 1 186 ? 0.57200   -18.11000 31.35300 1.000 73.44038  ? 186 LEU A O    1 
ATOM   2893 C  CB   . LEU A 1 186 ? 3.30800   -19.90600 30.68200 1.000 68.88194  ? 186 LEU A CB   1 
ATOM   2894 C  CG   . LEU A 1 186 ? 4.78200   -20.12200 31.01800 1.000 69.81363  ? 186 LEU A CG   1 
ATOM   2895 C  CD1  . LEU A 1 186 ? 5.01900   -21.55500 31.46600 1.000 71.17169  ? 186 LEU A CD1  1 
ATOM   2896 C  CD2  . LEU A 1 186 ? 5.64900   -19.77400 29.82000 1.000 68.61612  ? 186 LEU A CD2  1 
ATOM   2897 H  H    . LEU A 1 186 ? 2.89200   -18.04500 32.52100 1.000 81.63000  ? 186 LEU A H    1 
ATOM   2898 H  HA   . LEU A 1 186 ? 3.25000   -18.03700 29.83000 1.000 85.46000  ? 186 LEU A HA   1 
ATOM   2899 H  HB2  . LEU A 1 186 ? 2.78900   -20.35500 31.36700 1.000 82.77000  ? 186 LEU A HB2  1 
ATOM   2900 H  HB3  . LEU A 1 186 ? 3.14800   -20.32100 29.81900 1.000 82.77000  ? 186 LEU A HB3  1 
ATOM   2901 H  HG   . LEU A 1 186 ? 5.03600   -19.53800 31.75100 1.000 83.89000  ? 186 LEU A HG   1 
ATOM   2902 H  HD11 . LEU A 1 186 ? 5.95900   -21.66800 31.67900 1.000 85.52000  ? 186 LEU A HD11 1 
ATOM   2903 H  HD12 . LEU A 1 186 ? 4.47900   -21.73400 32.25100 1.000 85.52000  ? 186 LEU A HD12 1 
ATOM   2904 H  HD13 . LEU A 1 186 ? 4.76800   -22.15600 30.74700 1.000 85.52000  ? 186 LEU A HD13 1 
ATOM   2905 H  HD21 . LEU A 1 186 ? 6.57900   -19.92600 30.04800 1.000 82.45000  ? 186 LEU A HD21 1 
ATOM   2906 H  HD22 . LEU A 1 186 ? 5.39500   -20.33700 29.07200 1.000 82.45000  ? 186 LEU A HD22 1 
ATOM   2907 H  HD23 . LEU A 1 186 ? 5.51300   -18.84100 29.59200 1.000 82.45000  ? 186 LEU A HD23 1 
ATOM   2908 N  N    . ASN A 1 187 ? 0.88800   -18.72800 29.20700 1.000 73.09297  ? 187 ASN A N    1 
ATOM   2909 C  CA   . ASN A 1 187 ? -0.53100  -18.80000 28.88200 1.000 75.66434  ? 187 ASN A CA   1 
ATOM   2910 C  C    . ASN A 1 187 ? -0.73800  -19.95400 27.91500 1.000 74.24574  ? 187 ASN A C    1 
ATOM   2911 O  O    . ASN A 1 187 ? -0.14400  -19.97200 26.83300 1.000 72.31130  ? 187 ASN A O    1 
ATOM   2912 C  CB   . ASN A 1 187 ? -1.02800  -17.48200 28.27600 1.000 72.93506  ? 187 ASN A CB   1 
ATOM   2913 C  CG   . ASN A 1 187 ? -2.53100  -17.47100 28.03400 1.000 74.31417  ? 187 ASN A CG   1 
ATOM   2914 O  OD1  . ASN A 1 187 ? -3.00500  -16.86400 27.07400 1.000 76.91449  ? 187 ASN A OD1  1 
ATOM   2915 N  ND2  . ASN A 1 187 ? -3.28600  -18.13000 28.90700 1.000 75.57748  ? 187 ASN A ND2  1 
ATOM   2916 H  H    . ASN A 1 187 ? 1.40500   -18.90700 28.54300 1.000 87.82000  ? 187 ASN A H    1 
ATOM   2917 H  HA   . ASN A 1 187 ? -1.04700  -18.97400 29.68500 1.000 90.91000  ? 187 ASN A HA   1 
ATOM   2918 H  HB2  . ASN A 1 187 ? -0.81700  -16.75700 28.88400 1.000 87.64000  ? 187 ASN A HB2  1 
ATOM   2919 H  HB3  . ASN A 1 187 ? -0.58600  -17.34000 27.42400 1.000 87.64000  ? 187 ASN A HB3  1 
ATOM   2920 H  HD21 . ASN A 1 187 ? -4.14000  -18.14900 28.80900 1.000 90.81000  ? 187 ASN A HD21 1 
ATOM   2921 H  HD22 . ASN A 1 187 ? -2.92000  -18.53700 29.57100 1.000 90.81000  ? 187 ASN A HD22 1 
ATOM   2922 N  N    . VAL A 1 188 ? -1.56800  -20.91500 28.31100 1.000 75.86436  ? 188 VAL A N    1 
ATOM   2923 C  CA   . VAL A 1 188 ? -1.85800  -22.09600 27.50800 1.000 72.05864  ? 188 VAL A CA   1 
ATOM   2924 C  C    . VAL A 1 188 ? -3.24700  -21.92800 26.90900 1.000 76.04859  ? 188 VAL A C    1 
ATOM   2925 O  O    . VAL A 1 188 ? -4.23500  -21.78700 27.64100 1.000 79.98064  ? 188 VAL A O    1 
ATOM   2926 C  CB   . VAL A 1 188 ? -1.77000  -23.38100 28.34600 1.000 73.44038  ? 188 VAL A CB   1 
ATOM   2927 C  CG1  . VAL A 1 188 ? -1.79500  -24.60400 27.44300 1.000 72.90348  ? 188 VAL A CG1  1 
ATOM   2928 C  CG2  . VAL A 1 188 ? -0.51200  -23.37400 29.20800 1.000 70.84534  ? 188 VAL A CG2  1 
ATOM   2929 H  H    . VAL A 1 188 ? -1.98700  -20.90300 29.06200 1.000 91.15000  ? 188 VAL A H    1 
ATOM   2930 H  HA   . VAL A 1 188 ? -1.21600  -22.16000 26.78400 1.000 86.58000  ? 188 VAL A HA   1 
ATOM   2931 H  HB   . VAL A 1 188 ? -2.53800  -23.42500 28.93700 1.000 88.24000  ? 188 VAL A HB   1 
ATOM   2932 H  HG11 . VAL A 1 188 ? -1.73700  -25.40300 27.99100 1.000 87.60000  ? 188 VAL A HG11 1 
ATOM   2933 H  HG12 . VAL A 1 188 ? -2.62300  -24.60800 26.93900 1.000 87.60000  ? 188 VAL A HG12 1 
ATOM   2934 H  HG13 . VAL A 1 188 ? -1.03900  -24.56400 26.83600 1.000 87.60000  ? 188 VAL A HG13 1 
ATOM   2935 H  HG21 . VAL A 1 188 ? -0.46400  -24.20600 29.70400 1.000 85.13000  ? 188 VAL A HG21 1 
ATOM   2936 H  HG22 . VAL A 1 188 ? 0.26400   -23.28600 28.63300 1.000 85.13000  ? 188 VAL A HG22 1 
ATOM   2937 H  HG23 . VAL A 1 188 ? -0.55500  -22.62400 29.82200 1.000 85.13000  ? 188 VAL A HG23 1 
ATOM   2938 N  N    . VAL A 1 189 ? -3.32500  -21.94600 25.58100 1.000 76.03806  ? 189 VAL A N    1 
ATOM   2939 C  CA   . VAL A 1 189 ? -4.56700  -21.71000 24.85200 1.000 80.73600  ? 189 VAL A CA   1 
ATOM   2940 C  C    . VAL A 1 189 ? -5.00900  -23.02200 24.22000 1.000 80.84390  ? 189 VAL A C    1 
ATOM   2941 O  O    . VAL A 1 189 ? -4.30700  -23.57700 23.36400 1.000 77.86197  ? 189 VAL A O    1 
ATOM   2942 C  CB   . VAL A 1 189 ? -4.39600  -20.61900 23.78200 1.000 78.51205  ? 189 VAL A CB   1 
ATOM   2943 C  CG1  . VAL A 1 189 ? -5.73900  -20.27300 23.15300 1.000 79.27793  ? 189 VAL A CG1  1 
ATOM   2944 C  CG2  . VAL A 1 189 ? -3.74800  -19.37700 24.38100 1.000 82.62043  ? 189 VAL A CG2  1 
ATOM   2945 H  H    . VAL A 1 189 ? -2.65300  -22.09700 25.06700 1.000 91.36000  ? 189 VAL A H    1 
ATOM   2946 H  HA   . VAL A 1 189 ? -5.25200  -21.42800 25.47800 1.000 97.00000  ? 189 VAL A HA   1 
ATOM   2947 H  HB   . VAL A 1 189 ? -3.81300  -20.95500 23.08400 1.000 94.33000  ? 189 VAL A HB   1 
ATOM   2948 H  HG11 . VAL A 1 189 ? -5.60600  -19.58300 22.48500 1.000 95.25000  ? 189 VAL A HG11 1 
ATOM   2949 H  HG12 . VAL A 1 189 ? -6.10800  -21.06900 22.73800 1.000 95.25000  ? 189 VAL A HG12 1 
ATOM   2950 H  HG13 . VAL A 1 189 ? -6.33900  -19.95300 23.84500 1.000 95.25000  ? 189 VAL A HG13 1 
ATOM   2951 H  HG21 . VAL A 1 189 ? -3.65500  -18.70400 23.68900 1.000 99.26000  ? 189 VAL A HG21 1 
ATOM   2952 H  HG22 . VAL A 1 189 ? -4.31100  -19.04100 25.09600 1.000 99.26000  ? 189 VAL A HG22 1 
ATOM   2953 H  HG23 . VAL A 1 189 ? -2.87500  -19.61400 24.73100 1.000 99.26000  ? 189 VAL A HG23 1 
ATOM   2954 N  N    . CYS A 1 190 ? -6.17000  -23.51700 24.63900 1.000 81.22026  ? 190 CYS A N    1 
ATOM   2955 C  CA   . CYS A 1 190 ? -6.80700  -24.67500 24.02700 1.000 80.12013  ? 190 CYS A CA   1 
ATOM   2956 C  C    . CYS A 1 190 ? -8.11300  -24.23200 23.38400 1.000 80.49913  ? 190 CYS A C    1 
ATOM   2957 O  O    . CYS A 1 190 ? -8.93800  -23.57800 24.03200 1.000 82.60990  ? 190 CYS A O    1 
ATOM   2958 C  CB   . CYS A 1 190 ? -7.07300  -25.77400 25.05700 1.000 81.03866  ? 190 CYS A CB   1 
ATOM   2959 S  SG   . CYS A 1 190 ? -7.86900  -27.24600 24.36400 1.000 75.71171  ? 190 CYS A SG   1 
ATOM   2960 H  H    . CYS A 1 190 ? -6.61800  -23.18900 25.29500 1.000 97.58000  ? 190 CYS A H    1 
ATOM   2961 H  HA   . CYS A 1 190 ? -6.22700  -25.04300 23.34200 1.000 96.26000  ? 190 CYS A HA   1 
ATOM   2962 H  HB2  . CYS A 1 190 ? -6.22700  -26.04900 25.44400 1.000 97.36000  ? 190 CYS A HB2  1 
ATOM   2963 H  HB3  . CYS A 1 190 ? -7.65400  -25.42000 25.74800 1.000 97.36000  ? 190 CYS A HB3  1 
ATOM   2964 N  N    . LYS A 1 191 ? -8.29800  -24.58700 22.11000 1.000 81.33870  ? 191 LYS A N    1 
ATOM   2965 C  CA   . LYS A 1 191 ? -9.50000  -24.17500 21.39500 1.000 77.79354  ? 191 LYS A CA   1 
ATOM   2966 C  C    . LYS A 1 191 ? -10.77300 -24.68800 22.05800 1.000 81.84402  ? 191 LYS A C    1 
ATOM   2967 O  O    . LYS A 1 191 ? -11.85000 -24.13000 21.82100 1.000 80.49649  ? 191 LYS A O    1 
ATOM   2968 C  CB   . LYS A 1 191 ? -9.44500  -24.66300 19.94600 1.000 84.83912  ? 191 LYS A CB   1 
ATOM   2969 C  CG   . LYS A 1 191 ? -8.19200  -24.25200 19.18500 1.000 86.26297  ? 191 LYS A CG   1 
ATOM   2970 C  CD   . LYS A 1 191 ? -8.43600  -24.23500 17.67600 1.000 92.27159  ? 191 LYS A CD   1 
ATOM   2971 C  CE   . LYS A 1 191 ? -8.57300  -25.64300 17.10400 1.000 89.32913  ? 191 LYS A CE   1 
ATOM   2972 N  NZ   . LYS A 1 191 ? -9.43800  -25.69000 15.88800 1.000 88.54483  ? 191 LYS A NZ   1 
ATOM   2973 H  H    . LYS A 1 191 ? -7.74900  -25.05900 21.64600 1.000 97.72000  ? 191 LYS A H    1 
ATOM   2974 H  HA   . LYS A 1 191 ? -9.53500  -23.20600 21.38700 1.000 93.47000  ? 191 LYS A HA   1 
ATOM   2975 H  HB2  . LYS A 1 191 ? -9.48300  -25.63200 19.94500 1.000 101.92000 ? 191 LYS A HB2  1 
ATOM   2976 H  HB3  . LYS A 1 191 ? -10.20800 -24.30000 19.46900 1.000 101.92000 ? 191 LYS A HB3  1 
ATOM   2977 H  HG2  . LYS A 1 191 ? -7.92500  -23.36100 19.46100 1.000 103.63000 ? 191 LYS A HG2  1 
ATOM   2978 H  HG3  . LYS A 1 191 ? -7.48000  -24.88400 19.37200 1.000 103.63000 ? 191 LYS A HG3  1 
ATOM   2979 H  HD2  . LYS A 1 191 ? -9.25600  -23.75100 17.49000 1.000 110.84000 ? 191 LYS A HD2  1 
ATOM   2980 H  HD3  . LYS A 1 191 ? -7.68800  -23.80100 17.23600 1.000 110.84000 ? 191 LYS A HD3  1 
ATOM   2981 H  HE2  . LYS A 1 191 ? -7.69400  -25.97300 16.86000 1.000 107.31000 ? 191 LYS A HE2  1 
ATOM   2982 H  HE3  . LYS A 1 191 ? -8.96800  -26.22100 17.77600 1.000 107.31000 ? 191 LYS A HE3  1 
ATOM   2983 H  HZ1  . LYS A 1 191 ? -9.49400  -26.52600 15.58600 1.000 106.37000 ? 191 LYS A HZ1  1 
ATOM   2984 H  HZ2  . LYS A 1 191 ? -10.25600 -25.39900 16.08500 1.000 106.37000 ? 191 LYS A HZ2  1 
ATOM   2985 H  HZ3  . LYS A 1 191 ? -9.09400  -25.17500 15.24900 1.000 106.37000 ? 191 LYS A HZ3  1 
ATOM   2986 N  N    . THR A 1 192 ? -10.67600 -25.73100 22.88300 1.000 84.53119  ? 192 THR A N    1 
ATOM   2987 C  CA   . THR A 1 192 ? -11.83700 -26.30600 23.55100 1.000 87.64998  ? 192 THR A CA   1 
ATOM   2988 C  C    . THR A 1 192 ? -11.94200 -25.91700 25.01900 1.000 86.28929  ? 192 THR A C    1 
ATOM   2989 O  O    . THR A 1 192 ? -13.05700 -25.81700 25.54100 1.000 86.79199  ? 192 THR A O    1 
ATOM   2990 C  CB   . THR A 1 192 ? -11.80400 -27.83700 23.44400 1.000 85.16284  ? 192 THR A CB   1 
ATOM   2991 O  OG1  . THR A 1 192 ? -12.07200 -28.23300 22.09300 1.000 80.64651  ? 192 THR A OG1  1 
ATOM   2992 C  CG2  . THR A 1 192 ? -12.83700 -28.47400 24.37000 1.000 79.63586  ? 192 THR A CG2  1 
ATOM   2993 H  H    . THR A 1 192 ? -9.93700  -26.12700 23.07300 1.000 101.55000 ? 192 THR A H    1 
ATOM   2994 H  HA   . THR A 1 192 ? -12.63900 -25.99200 23.10300 1.000 105.29000 ? 192 THR A HA   1 
ATOM   2995 H  HB   . THR A 1 192 ? -10.92600 -28.15400 23.70900 1.000 102.31000 ? 192 THR A HB   1 
ATOM   2996 H  HG1  . THR A 1 192 ? -12.04500 -29.07000 22.02800 1.000 96.89000  ? 192 THR A HG1  1 
ATOM   2997 H  HG21 . THR A 1 192 ? -13.02100 -29.38300 24.08600 1.000 95.67000  ? 192 THR A HG21 1 
ATOM   2998 H  HG22 . THR A 1 192 ? -12.50100 -28.49000 25.28000 1.000 95.67000  ? 192 THR A HG22 1 
ATOM   2999 H  HG23 . THR A 1 192 ? -13.66100 -27.96400 24.34800 1.000 95.67000  ? 192 THR A HG23 1 
ATOM   3000 N  N    . CYS A 1 193 ? -10.81500 -25.69200 25.69500 1.000 88.02371  ? 193 CYS A N    1 
ATOM   3001 C  CA   . CYS A 1 193 ? -10.80400 -25.39400 27.12100 1.000 91.81890  ? 193 CYS A CA   1 
ATOM   3002 C  C    . CYS A 1 193 ? -10.37400 -23.96200 27.42100 1.000 90.64245  ? 193 CYS A C    1 
ATOM   3003 O  O    . CYS A 1 193 ? -10.06300 -23.64800 28.57600 1.000 92.88219  ? 193 CYS A O    1 
ATOM   3004 C  CB   . CYS A 1 193 ? -9.89100  -26.38200 27.85300 1.000 93.54806  ? 193 CYS A CB   1 
ATOM   3005 S  SG   . CYS A 1 193 ? -10.03500 -28.09600 27.27100 1.000 98.20914  ? 193 CYS A SG   1 
ATOM   3006 H  H    . CYS A 1 193 ? -10.03200 -25.70900 25.34000 1.000 105.74000 ? 193 CYS A H    1 
ATOM   3007 H  HA   . CYS A 1 193 ? -11.70400 -25.50200 27.46500 1.000 110.29000 ? 193 CYS A HA   1 
ATOM   3008 H  HB2  . CYS A 1 193 ? -8.97000  -26.10500 27.72700 1.000 112.37000 ? 193 CYS A HB2  1 
ATOM   3009 H  HB3  . CYS A 1 193 ? -10.11600 -26.37100 28.79600 1.000 112.37000 ? 193 CYS A HB3  1 
ATOM   3010 N  N    . GLY A 1 194 ? -10.34700 -23.08800 26.41600 1.000 89.09752  ? 194 GLY A N    1 
ATOM   3011 C  CA   . GLY A 1 194 ? -10.05200 -21.68900 26.66000 1.000 92.68480  ? 194 GLY A CA   1 
ATOM   3012 C  C    . GLY A 1 194 ? -8.60400  -21.45000 27.05800 1.000 90.75825  ? 194 GLY A C    1 
ATOM   3013 O  O    . GLY A 1 194 ? -7.69600  -22.21700 26.72300 1.000 85.84714  ? 194 GLY A O    1 
ATOM   3014 H  H    . GLY A 1 194 ? -10.49600 -23.28200 25.59100 1.000 107.03000 ? 194 GLY A H    1 
ATOM   3015 H  HA2  . GLY A 1 194 ? -10.23300 -21.17900 25.85400 1.000 111.33000 ? 194 GLY A HA2  1 
ATOM   3016 H  HA3  . GLY A 1 194 ? -10.62000 -21.36200 27.37500 1.000 111.33000 ? 194 GLY A HA3  1 
ATOM   3017 N  N    . GLN A 1 195 ? -8.39200  -20.35900 27.78800 1.000 92.86377  ? 195 GLN A N    1 
ATOM   3018 C  CA   . GLN A 1 195 ? -7.07100  -19.92700 28.21600 1.000 88.62905  ? 195 GLN A CA   1 
ATOM   3019 C  C    . GLN A 1 195 ? -6.79000  -20.38100 29.64400 1.000 88.69748  ? 195 GLN A C    1 
ATOM   3020 O  O    . GLN A 1 195 ? -7.69600  -20.73000 30.40400 1.000 92.22948  ? 195 GLN A O    1 
ATOM   3021 C  CB   . GLN A 1 195 ? -6.94700  -18.40200 28.12400 1.000 86.09453  ? 195 GLN A CB   1 
ATOM   3022 C  CG   . GLN A 1 195 ? -6.30300  -17.90200 26.83900 1.000 89.26333  ? 195 GLN A CG   1 
ATOM   3023 C  CD   . GLN A 1 195 ? -6.94900  -16.63400 26.30900 1.000 95.19826  ? 195 GLN A CD   1 
ATOM   3024 O  OE1  . GLN A 1 195 ? -7.75200  -15.99900 26.99200 1.000 99.88040  ? 195 GLN A OE1  1 
ATOM   3025 N  NE2  . GLN A 1 195 ? -6.59800  -16.25900 25.08400 1.000 95.62199  ? 195 GLN A NE2  1 
ATOM   3026 H  H    . GLN A 1 195 ? -9.02100  -19.83700 28.05600 1.000 111.55000 ? 195 GLN A H    1 
ATOM   3027 H  HA   . GLN A 1 195 ? -6.40400  -20.32600 27.63500 1.000 106.47000 ? 195 GLN A HA   1 
ATOM   3028 H  HB2  . GLN A 1 195 ? -7.83400  -18.01500 28.17800 1.000 103.43000 ? 195 GLN A HB2  1 
ATOM   3029 H  HB3  . GLN A 1 195 ? -6.40400  -18.09000 28.86500 1.000 103.43000 ? 195 GLN A HB3  1 
ATOM   3030 H  HG2  . GLN A 1 195 ? -5.36600  -17.71300 27.00800 1.000 107.23000 ? 195 GLN A HG2  1 
ATOM   3031 H  HG3  . GLN A 1 195 ? -6.38500  -18.58700 26.15700 1.000 107.23000 ? 195 GLN A HG3  1 
ATOM   3032 H  HE21 . GLN A 1 195 ? -6.03300  -16.72800 24.63600 1.000 114.86000 ? 195 GLN A HE21 1 
ATOM   3033 H  HE22 . GLN A 1 195 ? -6.93600  -15.54800 24.73900 1.000 114.86000 ? 195 GLN A HE22 1 
ATOM   3034 N  N    . GLN A 1 196 ? -5.50600  -20.36700 30.00200 1.000 86.91305  ? 196 GLN A N    1 
ATOM   3035 C  CA   . GLN A 1 196 ? -5.09000  -20.70900 31.36100 1.000 84.95755  ? 196 GLN A CA   1 
ATOM   3036 C  C    . GLN A 1 196 ? -3.69000  -20.14900 31.57400 1.000 81.66769  ? 196 GLN A C    1 
ATOM   3037 O  O    . GLN A 1 196 ? -2.71800  -20.69400 31.04200 1.000 81.50977  ? 196 GLN A O    1 
ATOM   3038 C  CB   . GLN A 1 196 ? -5.12200  -22.21800 31.57800 1.000 87.55787  ? 196 GLN A CB   1 
ATOM   3039 C  CG   . GLN A 1 196 ? -4.63600  -22.67100 32.95100 1.000 86.73408  ? 196 GLN A CG   1 
ATOM   3040 C  CD   . GLN A 1 196 ? -5.15400  -21.80000 34.08300 1.000 94.29025  ? 196 GLN A CD   1 
ATOM   3041 O  OE1  . GLN A 1 196 ? -4.64400  -20.70600 34.32400 1.000 93.15591  ? 196 GLN A OE1  1 
ATOM   3042 N  NE2  . GLN A 1 196 ? -6.17400  -22.28500 34.78300 1.000 92.47425  ? 196 GLN A NE2  1 
ATOM   3043 H  H    . GLN A 1 196 ? -4.85700  -20.16300 29.47600 1.000 104.41000 ? 196 GLN A H    1 
ATOM   3044 H  HA   . GLN A 1 196 ? -5.69200  -20.29400 31.99800 1.000 102.06000 ? 196 GLN A HA   1 
ATOM   3045 H  HB2  . GLN A 1 196 ? -6.03700  -22.52500 31.47600 1.000 105.18000 ? 196 GLN A HB2  1 
ATOM   3046 H  HB3  . GLN A 1 196 ? -4.55500  -22.63800 30.91300 1.000 105.18000 ? 196 GLN A HB3  1 
ATOM   3047 H  HG2  . GLN A 1 196 ? -4.93900  -23.57800 33.11000 1.000 104.19000 ? 196 GLN A HG2  1 
ATOM   3048 H  HG3  . GLN A 1 196 ? -3.66600  -22.63700 32.96900 1.000 104.19000 ? 196 GLN A HG3  1 
ATOM   3049 H  HE21 . GLN A 1 196 ? -6.50400  -23.05400 34.58500 1.000 111.08000 ? 196 GLN A HE21 1 
ATOM   3050 H  HE22 . GLN A 1 196 ? -6.50300  -21.82900 35.43400 1.000 111.08000 ? 196 GLN A HE22 1 
ATOM   3051 N  N    . GLN A 1 197 ? -3.59400  -19.06900 32.34500 1.000 80.78863  ? 197 GLN A N    1 
ATOM   3052 C  CA   . GLN A 1 197 ? -2.32000  -18.42800 32.63300 1.000 79.08843  ? 197 GLN A CA   1 
ATOM   3053 C  C    . GLN A 1 197 ? -1.66200  -19.08000 33.84200 1.000 75.41431  ? 197 GLN A C    1 
ATOM   3054 O  O    . GLN A 1 197 ? -2.34000  -19.48800 34.78900 1.000 74.26680  ? 197 GLN A O    1 
ATOM   3055 C  CB   . GLN A 1 197 ? -2.52100  -16.93300 32.88900 1.000 79.12528  ? 197 GLN A CB   1 
ATOM   3056 C  CG   . GLN A 1 197 ? -1.28900  -16.08000 32.63300 1.000 79.68587  ? 197 GLN A CG   1 
ATOM   3057 C  CD   . GLN A 1 197 ? -1.41300  -14.68900 33.22600 1.000 80.20962  ? 197 GLN A CD   1 
ATOM   3058 O  OE1  . GLN A 1 197 ? -1.49100  -13.69600 32.50100 1.000 78.76997  ? 197 GLN A OE1  1 
ATOM   3059 N  NE2  . GLN A 1 197 ? -1.43000  -14.61100 34.55200 1.000 77.39086  ? 197 GLN A NE2  1 
ATOM   3060 H  H    . GLN A 1 197 ? -4.26600  -18.68400 32.71900 1.000 97.06000  ? 197 GLN A H    1 
ATOM   3061 H  HA   . GLN A 1 197 ? -1.72600  -18.53000 31.87300 1.000 95.02000  ? 197 GLN A HA   1 
ATOM   3062 H  HB2  . GLN A 1 197 ? -3.22700  -16.61200 32.30600 1.000 95.06000  ? 197 GLN A HB2  1 
ATOM   3063 H  HB3  . GLN A 1 197 ? -2.77600  -16.81000 33.81700 1.000 95.06000  ? 197 GLN A HB3  1 
ATOM   3064 H  HG2  . GLN A 1 197 ? -0.51700  -16.51000 33.03200 1.000 95.74000  ? 197 GLN A HG2  1 
ATOM   3065 H  HG3  . GLN A 1 197 ? -1.16000  -15.98900 31.67600 1.000 95.74000  ? 197 GLN A HG3  1 
ATOM   3066 H  HE21 . GLN A 1 197 ? -1.37300  -15.32600 35.02600 1.000 92.98000  ? 197 GLN A HE21 1 
ATOM   3067 H  HE22 . GLN A 1 197 ? -1.49900  -13.84500 34.93700 1.000 92.98000  ? 197 GLN A HE22 1 
ATOM   3068 N  N    . THR A 1 198 ? -0.33400  -19.17600 33.80100 1.000 77.12240  ? 198 THR A N    1 
ATOM   3069 C  CA   . THR A 1 198 ? 0.44000   -19.76700 34.88300 1.000 73.62988  ? 198 THR A CA   1 
ATOM   3070 C  C    . THR A 1 198 ? 1.65700   -18.89900 35.16300 1.000 72.05338  ? 198 THR A C    1 
ATOM   3071 O  O    . THR A 1 198 ? 2.22500   -18.28800 34.25400 1.000 69.94260  ? 198 THR A O    1 
ATOM   3072 C  CB   . THR A 1 198 ? 0.89300   -21.19600 34.55000 1.000 78.41203  ? 198 THR A CB   1 
ATOM   3073 O  OG1  . THR A 1 198 ? -0.15900  -21.89100 33.86800 1.000 83.63634  ? 198 THR A OG1  1 
ATOM   3074 C  CG2  . THR A 1 198 ? 1.26200   -21.95100 35.82000 1.000 82.08616  ? 198 THR A CG2  1 
ATOM   3075 H  H    . THR A 1 198 ? 0.14800   -18.89900 33.14500 1.000 92.66000  ? 198 THR A H    1 
ATOM   3076 H  HA   . THR A 1 198 ? -0.10700  -19.80200 35.68400 1.000 88.47000  ? 198 THR A HA   1 
ATOM   3077 H  HB   . THR A 1 198 ? 1.67600   -21.16100 33.97800 1.000 94.21000  ? 198 THR A HB   1 
ATOM   3078 H  HG1  . THR A 1 198 ? 0.09500   -22.66400 33.66000 1.000 100.48000 ? 198 THR A HG1  1 
ATOM   3079 H  HG21 . THR A 1 198 ? 1.51900   -22.86100 35.60300 1.000 98.62000  ? 198 THR A HG21 1 
ATOM   3080 H  HG22 . THR A 1 198 ? 2.00400   -21.51100 36.26400 1.000 98.62000  ? 198 THR A HG22 1 
ATOM   3081 H  HG23 . THR A 1 198 ? 0.50300   -21.97400 36.42500 1.000 98.62000  ? 198 THR A HG23 1 
ATOM   3082 N  N    . THR A 1 199 ? 2.05600   -18.85800 36.43300 1.000 69.05302  ? 199 THR A N    1 
ATOM   3083 C  CA   . THR A 1 199 ? 3.17300   -18.04400 36.89100 1.000 65.14728  ? 199 THR A CA   1 
ATOM   3084 C  C    . THR A 1 199 ? 4.22800   -18.94300 37.52000 1.000 65.53681  ? 199 THR A C    1 
ATOM   3085 O  O    . THR A 1 199 ? 3.89900   -19.83300 38.31100 1.000 65.58681  ? 199 THR A O    1 
ATOM   3086 C  CB   . THR A 1 199 ? 2.70500   -16.98800 37.90000 1.000 66.81327  ? 199 THR A CB   1 
ATOM   3087 O  OG1  . THR A 1 199 ? 1.95500   -15.97300 37.21900 1.000 71.42962  ? 199 THR A OG1  1 
ATOM   3088 C  CG2  . THR A 1 199 ? 3.89200   -16.35000 38.60700 1.000 67.37387  ? 199 THR A CG2  1 
ATOM   3089 H  H    . THR A 1 199 ? 1.68200   -19.30800 37.06400 1.000 82.98000  ? 199 THR A H    1 
ATOM   3090 H  HA   . THR A 1 199 ? 3.57500   -17.58800 36.13500 1.000 78.29000  ? 199 THR A HA   1 
ATOM   3091 H  HB   . THR A 1 199 ? 2.14500   -17.41100 38.56900 1.000 80.29000  ? 199 THR A HB   1 
ATOM   3092 H  HG1  . THR A 1 199 ? 1.71100   -15.38200 37.76400 1.000 85.83000  ? 199 THR A HG1  1 
ATOM   3093 H  HG21 . THR A 1 199 ? 3.62800   -15.50300 39.00000 1.000 80.96000  ? 199 THR A HG21 1 
ATOM   3094 H  HG22 . THR A 1 199 ? 4.21300   -16.93700 39.31000 1.000 80.96000  ? 199 THR A HG22 1 
ATOM   3095 H  HG23 . THR A 1 199 ? 4.61000   -16.19400 37.97400 1.000 80.96000  ? 199 THR A HG23 1 
ATOM   3096 N  N    . LEU A 1 200 ? 5.49100   -18.70600 37.16700 1.000 64.41825  ? 200 LEU A N    1 
ATOM   3097 C  CA   . LEU A 1 200 ? 6.61100   -19.48300 37.67500 1.000 63.97609  ? 200 LEU A CA   1 
ATOM   3098 C  C    . LEU A 1 200 ? 7.65200   -18.54600 38.27100 1.000 63.22074  ? 200 LEU A C    1 
ATOM   3099 O  O    . LEU A 1 200 ? 7.81700   -17.40900 37.82000 1.000 61.32051  ? 200 LEU A O    1 
ATOM   3100 C  CB   . LEU A 1 200 ? 7.24900   -20.33600 36.57200 1.000 57.58848  ? 200 LEU A CB   1 
ATOM   3101 C  CG   . LEU A 1 200 ? 6.29100   -21.26300 35.82200 1.000 67.49493  ? 200 LEU A CG   1 
ATOM   3102 C  CD1  . LEU A 1 200 ? 6.92400   -21.75400 34.52900 1.000 61.33893  ? 200 LEU A CD1  1 
ATOM   3103 C  CD2  . LEU A 1 200 ? 5.88300   -22.43400 36.70600 1.000 68.27924  ? 200 LEU A CD2  1 
ATOM   3104 H  H    . LEU A 1 200 ? 5.72600   -18.08500 36.62100 1.000 77.41000  ? 200 LEU A H    1 
ATOM   3105 H  HA   . LEU A 1 200 ? 6.30300   -20.07800 38.37700 1.000 76.88000  ? 200 LEU A HA   1 
ATOM   3106 H  HB2  . LEU A 1 200 ? 7.64600   -19.74000 35.91800 1.000 69.22000  ? 200 LEU A HB2  1 
ATOM   3107 H  HB3  . LEU A 1 200 ? 7.93500   -20.89100 36.97400 1.000 69.22000  ? 200 LEU A HB3  1 
ATOM   3108 H  HG   . LEU A 1 200 ? 5.48800   -20.77000 35.59100 1.000 81.11000  ? 200 LEU A HG   1 
ATOM   3109 H  HD11 . LEU A 1 200 ? 6.29800   -22.33900 34.07300 1.000 73.72000  ? 200 LEU A HD11 1 
ATOM   3110 H  HD12 . LEU A 1 200 ? 7.13000   -20.99000 33.96800 1.000 73.72000  ? 200 LEU A HD12 1 
ATOM   3111 H  HD13 . LEU A 1 200 ? 7.73700   -22.23900 34.73900 1.000 73.72000  ? 200 LEU A HD13 1 
ATOM   3112 H  HD21 . LEU A 1 200 ? 5.27700   -23.00700 36.21000 1.000 82.05000  ? 200 LEU A HD21 1 
ATOM   3113 H  HD22 . LEU A 1 200 ? 6.67600   -22.93100 36.95800 1.000 82.05000  ? 200 LEU A HD22 1 
ATOM   3114 H  HD23 . LEU A 1 200 ? 5.44000   -22.09200 37.49900 1.000 82.05000  ? 200 LEU A HD23 1 
ATOM   3115 N  N    . LYS A 1 201 ? 8.35400   -19.03700 39.29200 1.000 61.87584  ? 201 LYS A N    1 
ATOM   3116 C  CA   . LYS A 1 201 ? 9.33500   -18.24000 40.01300 1.000 65.89211  ? 201 LYS A CA   1 
ATOM   3117 C  C    . LYS A 1 201 ? 10.59600  -19.06500 40.22700 1.000 62.14692  ? 201 LYS A C    1 
ATOM   3118 O  O    . LYS A 1 201 ? 10.57800  -20.29600 40.16700 1.000 65.37889  ? 201 LYS A O    1 
ATOM   3119 C  CB   . LYS A 1 201 ? 8.79300   -17.76100 41.37000 1.000 65.91843  ? 201 LYS A CB   1 
ATOM   3120 C  CG   . LYS A 1 201 ? 7.46000   -17.01800 41.30400 1.000 73.00612  ? 201 LYS A CG   1 
ATOM   3121 C  CD   . LYS A 1 201 ? 7.64600   -15.50900 41.40300 1.000 74.12731  ? 201 LYS A CD   1 
ATOM   3122 C  CE   . LYS A 1 201 ? 6.35500   -14.80500 41.80700 1.000 84.28642  ? 201 LYS A CE   1 
ATOM   3123 N  NZ   . LYS A 1 201 ? 5.86300   -15.22400 43.15100 1.000 91.07408  ? 201 LYS A NZ   1 
ATOM   3124 H  H    . LYS A 1 201 ? 8.27500   -19.84100 39.58700 1.000 74.36000  ? 201 LYS A H    1 
ATOM   3125 H  HA   . LYS A 1 201 ? 9.56300   -17.46300 39.48000 1.000 79.18000  ? 201 LYS A HA   1 
ATOM   3126 H  HB2  . LYS A 1 201 ? 8.66700   -18.53500 41.94200 1.000 79.21000  ? 201 LYS A HB2  1 
ATOM   3127 H  HB3  . LYS A 1 201 ? 9.44300   -17.15900 41.76500 1.000 79.21000  ? 201 LYS A HB3  1 
ATOM   3128 H  HG2  . LYS A 1 201 ? 7.02600   -17.21500 40.45900 1.000 87.72000  ? 201 LYS A HG2  1 
ATOM   3129 H  HG3  . LYS A 1 201 ? 6.89800   -17.30400 42.04000 1.000 87.72000  ? 201 LYS A HG3  1 
ATOM   3130 H  HD2  . LYS A 1 201 ? 8.32000   -15.31200 42.07200 1.000 89.07000  ? 201 LYS A HD2  1 
ATOM   3131 H  HD3  . LYS A 1 201 ? 7.92300   -15.16200 40.54100 1.000 89.07000  ? 201 LYS A HD3  1 
ATOM   3132 H  HE2  . LYS A 1 201 ? 6.51100   -13.84800 41.83000 1.000 101.26000 ? 201 LYS A HE2  1 
ATOM   3133 H  HE3  . LYS A 1 201 ? 5.66600   -15.01300 41.15700 1.000 101.26000 ? 201 LYS A HE3  1 
ATOM   3134 H  HZ1  . LYS A 1 201 ? 5.18200   -14.70800 43.40000 1.000 109.40000 ? 201 LYS A HZ1  1 
ATOM   3135 H  HZ2  . LYS A 1 201 ? 5.58900   -16.07000 43.12400 1.000 109.40000 ? 201 LYS A HZ2  1 
ATOM   3136 H  HZ3  . LYS A 1 201 ? 6.51600   -15.15000 43.75100 1.000 109.40000 ? 201 LYS A HZ3  1 
ATOM   3137 N  N    . GLY A 1 202 ? 11.70100  -18.36300 40.47300 1.000 62.14692  ? 202 GLY A N    1 
ATOM   3138 C  CA   . GLY A 1 202 ? 12.94400  -19.04300 40.80100 1.000 56.25938  ? 202 GLY A CA   1 
ATOM   3139 C  C    . GLY A 1 202 ? 13.47500  -19.86500 39.64200 1.000 54.31704  ? 202 GLY A C    1 
ATOM   3140 O  O    . GLY A 1 202 ? 13.46100  -19.43900 38.48200 1.000 56.66206  ? 202 GLY A O    1 
ATOM   3141 H  H    . GLY A 1 202 ? 11.75500  -17.50500 40.45600 1.000 74.69000  ? 202 GLY A H    1 
ATOM   3142 H  HA2  . GLY A 1 202 ? 13.61500  -18.38600 41.04300 1.000 67.63000  ? 202 GLY A HA2  1 
ATOM   3143 H  HA3  . GLY A 1 202 ? 12.79700  -19.63600 41.55500 1.000 67.63000  ? 202 GLY A HA3  1 
ATOM   3144 N  N    . VAL A 1 203 ? 13.96000  -21.06700 39.96500 1.000 52.77212  ? 203 VAL A N    1 
ATOM   3145 C  CA   . VAL A 1 203 ? 14.56200  -21.93200 38.95400 1.000 51.38511  ? 203 VAL A CA   1 
ATOM   3146 C  C    . VAL A 1 203 ? 13.56600  -22.22100 37.83900 1.000 53.81435  ? 203 VAL A C    1 
ATOM   3147 O  O    . VAL A 1 203 ? 13.89200  -22.12600 36.65000 1.000 52.06940  ? 203 VAL A O    1 
ATOM   3148 C  CB   . VAL A 1 203 ? 15.07000  -23.23500 39.60000 1.000 55.44612  ? 203 VAL A CB   1 
ATOM   3149 C  CG1  . VAL A 1 203 ? 15.56100  -24.20200 38.53000 1.000 52.94319  ? 203 VAL A CG1  1 
ATOM   3150 C  CG2  . VAL A 1 203 ? 16.16800  -22.93600 40.61100 1.000 55.59877  ? 203 VAL A CG2  1 
ATOM   3151 H  H    . VAL A 1 203 ? 13.95100  -21.40100 40.75800 1.000 63.44000  ? 203 VAL A H    1 
ATOM   3152 H  HA   . VAL A 1 203 ? 15.32100  -21.46900 38.56700 1.000 61.78000  ? 203 VAL A HA   1 
ATOM   3153 H  HB   . VAL A 1 203 ? 14.33800  -23.65900 40.07300 1.000 66.65000  ? 203 VAL A HB   1 
ATOM   3154 H  HG11 . VAL A 1 203 ? 16.09400  -24.89500 38.95100 1.000 63.64000  ? 203 VAL A HG11 1 
ATOM   3155 H  HG12 . VAL A 1 203 ? 14.79500  -24.59800 38.08600 1.000 63.64000  ? 203 VAL A HG12 1 
ATOM   3156 H  HG13 . VAL A 1 203 ? 16.10000  -23.71600 37.88700 1.000 63.64000  ? 203 VAL A HG13 1 
ATOM   3157 H  HG21 . VAL A 1 203 ? 16.48600  -23.77200 40.98700 1.000 66.83000  ? 203 VAL A HG21 1 
ATOM   3158 H  HG22 . VAL A 1 203 ? 16.89500  -22.47800 40.16200 1.000 66.83000  ? 203 VAL A HG22 1 
ATOM   3159 H  HG23 . VAL A 1 203 ? 15.80600  -22.37400 41.31300 1.000 66.83000  ? 203 VAL A HG23 1 
ATOM   3160 N  N    . GLU A 1 204 ? 12.33500  -22.58000 38.20800 1.000 53.36429  ? 204 GLU A N    1 
ATOM   3161 C  CA   . GLU A 1 204 ? 11.32000  -22.90200 37.21300 1.000 52.69053  ? 204 GLU A CA   1 
ATOM   3162 C  C    . GLU A 1 204 ? 11.03600  -21.74300 36.26700 1.000 54.10912  ? 204 GLU A C    1 
ATOM   3163 O  O    . GLU A 1 204 ? 10.40300  -21.95800 35.22700 1.000 53.79856  ? 204 GLU A O    1 
ATOM   3164 C  CB   . GLU A 1 204 ? 10.02600  -23.32700 37.91200 1.000 53.64327  ? 204 GLU A CB   1 
ATOM   3165 H  H    . GLU A 1 204 ? 12.06700  -22.64300 39.02200 1.000 64.15000  ? 204 GLU A H    1 
ATOM   3166 H  HA   . GLU A 1 204 ? 11.63400  -23.64900 36.68000 1.000 63.34000  ? 204 GLU A HA   1 
ATOM   3167 N  N    . ALA A 1 205 ? 11.48900  -20.53200 36.59200 1.000 50.72713  ? 205 ALA A N    1 
ATOM   3168 C  CA   . ALA A 1 205 ? 11.23200  -19.36800 35.75700 1.000 55.64878  ? 205 ALA A CA   1 
ATOM   3169 C  C    . ALA A 1 205 ? 12.26300  -19.17300 34.65200 1.000 53.00372  ? 205 ALA A C    1 
ATOM   3170 O  O    . ALA A 1 205 ? 11.98800  -18.43500 33.69900 1.000 58.28594  ? 205 ALA A O    1 
ATOM   3171 C  CB   . ALA A 1 205 ? 11.18200  -18.10400 36.62200 1.000 54.71445  ? 205 ALA A CB   1 
ATOM   3172 H  H    . ALA A 1 205 ? 11.95100  -20.36100 37.29700 1.000 60.98000  ? 205 ALA A H    1 
ATOM   3173 H  HA   . ALA A 1 205 ? 10.36700  -19.48100 35.33300 1.000 66.89000  ? 205 ALA A HA   1 
ATOM   3174 H  HB1  . ALA A 1 205 ? 11.00200  -17.33900 36.05400 1.000 65.77000  ? 205 ALA A HB1  1 
ATOM   3175 H  HB2  . ALA A 1 205 ? 10.47700  -18.20000 37.28100 1.000 65.77000  ? 205 ALA A HB2  1 
ATOM   3176 H  HB3  . ALA A 1 205 ? 12.03700  -17.99100 37.06600 1.000 65.77000  ? 205 ALA A HB3  1 
ATOM   3177 N  N    . VAL A 1 206 ? 13.43000  -19.81100 34.74600 1.000 50.09022  ? 206 VAL A N    1 
ATOM   3178 C  CA   . VAL A 1 206 ? 14.49500  -19.63900 33.76200 1.000 51.61672  ? 206 VAL A CA   1 
ATOM   3179 C  C    . VAL A 1 206 ? 14.73400  -20.88700 32.92800 1.000 52.48261  ? 206 VAL A C    1 
ATOM   3180 O  O    . VAL A 1 206 ? 15.59100  -20.86000 32.03200 1.000 49.95073  ? 206 VAL A O    1 
ATOM   3181 C  CB   . VAL A 1 206 ? 15.81100  -19.19800 34.43300 1.000 52.57209  ? 206 VAL A CB   1 
ATOM   3182 C  CG1  . VAL A 1 206 ? 15.56900  -18.02100 35.36500 1.000 53.30376  ? 206 VAL A CG1  1 
ATOM   3183 C  CG2  . VAL A 1 206 ? 16.44900  -20.36300 35.18200 1.000 54.13807  ? 206 VAL A CG2  1 
ATOM   3184 H  H    . VAL A 1 206 ? 13.63000  -20.35600 35.38000 1.000 60.22000  ? 206 VAL A H    1 
ATOM   3185 H  HA   . VAL A 1 206 ? 14.21900  -18.93800 33.15200 1.000 62.05000  ? 206 VAL A HA   1 
ATOM   3186 H  HB   . VAL A 1 206 ? 16.43200  -18.91100 33.74500 1.000 63.20000  ? 206 VAL A HB   1 
ATOM   3187 H  HG11 . VAL A 1 206 ? 16.42400  -17.67800 35.67000 1.000 64.08000  ? 206 VAL A HG11 1 
ATOM   3188 H  HG12 . VAL A 1 206 ? 15.08900  -17.33000 34.88200 1.000 64.08000  ? 206 VAL A HG12 1 
ATOM   3189 H  HG13 . VAL A 1 206 ? 15.04400  -18.32100 36.12300 1.000 64.08000  ? 206 VAL A HG13 1 
ATOM   3190 H  HG21 . VAL A 1 206 ? 17.09600  -20.01500 35.81600 1.000 65.08000  ? 206 VAL A HG21 1 
ATOM   3191 H  HG22 . VAL A 1 206 ? 15.75700  -20.85300 35.65200 1.000 65.08000  ? 206 VAL A HG22 1 
ATOM   3192 H  HG23 . VAL A 1 206 ? 16.89200  -20.94500 34.54400 1.000 65.08000  ? 206 VAL A HG23 1 
ATOM   3193 N  N    . MET A 1 207 ? 14.01100  -21.97600 33.18100 1.000 53.08794  ? 207 MET A N    1 
ATOM   3194 C  CA   . MET A 1 207 ? 14.22800  -23.23700 32.48500 1.000 51.63514  ? 207 MET A CA   1 
ATOM   3195 C  C    . MET A 1 207 ? 12.94800  -23.69600 31.80500 1.000 50.95348  ? 207 MET A C    1 
ATOM   3196 O  O    . MET A 1 207 ? 11.85800  -23.60200 32.37900 1.000 53.45378  ? 207 MET A O    1 
ATOM   3197 C  CB   . MET A 1 207 ? 14.70600  -24.32200 33.45300 1.000 48.90323  ? 207 MET A CB   1 
ATOM   3198 C  CG   . MET A 1 207 ? 16.21400  -24.45700 33.53900 1.000 56.06988  ? 207 MET A CG   1 
ATOM   3199 S  SD   . MET A 1 207 ? 16.73200  -25.20500 35.09500 1.000 57.88326  ? 207 MET A SD   1 
ATOM   3200 C  CE   . MET A 1 207 ? 17.15500  -26.85100 34.53600 1.000 55.97776  ? 207 MET A CE   1 
ATOM   3201 H  H    . MET A 1 207 ? 13.37700  -22.00600 33.76200 1.000 63.82000  ? 207 MET A H    1 
ATOM   3202 H  HA   . MET A 1 207 ? 14.91000  -23.10200 31.80900 1.000 62.08000  ? 207 MET A HA   1 
ATOM   3203 H  HB2  . MET A 1 207 ? 14.37800  -24.11100 34.34200 1.000 58.80000  ? 207 MET A HB2  1 
ATOM   3204 H  HB3  . MET A 1 207 ? 14.35000  -25.17600 33.16200 1.000 58.80000  ? 207 MET A HB3  1 
ATOM   3205 H  HG2  . MET A 1 207 ? 16.52600  -25.01900 32.81300 1.000 67.40000  ? 207 MET A HG2  1 
ATOM   3206 H  HG3  . MET A 1 207 ? 16.61800  -23.57700 33.47600 1.000 67.40000  ? 207 MET A HG3  1 
ATOM   3207 H  HE1  . MET A 1 207 ? 17.45700  -27.37400 35.29500 1.000 67.28000  ? 207 MET A HE1  1 
ATOM   3208 H  HE2  . MET A 1 207 ? 16.37000  -27.26200 34.14200 1.000 67.28000  ? 207 MET A HE2  1 
ATOM   3209 H  HE3  . MET A 1 207 ? 17.86300  -26.78800 33.87600 1.000 67.28000  ? 207 MET A HE3  1 
ATOM   3210 N  N    . TYR A 1 208 ? 13.08600  -24.19700 30.57900 1.000 51.48512  ? 208 TYR A N    1 
ATOM   3211 C  CA   . TYR A 1 208 ? 11.98000  -24.81600 29.86600 1.000 55.10398  ? 208 TYR A CA   1 
ATOM   3212 C  C    . TYR A 1 208 ? 12.49200  -26.01600 29.08400 1.000 53.66433  ? 208 TYR A C    1 
ATOM   3213 O  O    . TYR A 1 208 ? 13.57400  -25.96700 28.49100 1.000 50.26129  ? 208 TYR A O    1 
ATOM   3214 C  CB   . TYR A 1 208 ? 11.28400  -23.84300 28.91000 1.000 53.03004  ? 208 TYR A CB   1 
ATOM   3215 C  CG   . TYR A 1 208 ? 10.08600  -24.46700 28.23000 1.000 53.50905  ? 208 TYR A CG   1 
ATOM   3216 C  CD1  . TYR A 1 208 ? 8.89100   -24.64000 28.91400 1.000 55.86459  ? 208 TYR A CD1  1 
ATOM   3217 C  CD2  . TYR A 1 208 ? 10.15700  -24.90300 26.91500 1.000 58.33857  ? 208 TYR A CD2  1 
ATOM   3218 C  CE1  . TYR A 1 208 ? 7.79700   -25.21900 28.30600 1.000 58.85706  ? 208 TYR A CE1  1 
ATOM   3219 C  CE2  . TYR A 1 208 ? 9.06400   -25.48400 26.29600 1.000 60.00456  ? 208 TYR A CE2  1 
ATOM   3220 C  CZ   . TYR A 1 208 ? 7.88800   -25.63900 26.99700 1.000 61.57844  ? 208 TYR A CZ   1 
ATOM   3221 O  OH   . TYR A 1 208 ? 6.79700   -26.21700 26.38900 1.000 63.54972  ? 208 TYR A OH   1 
ATOM   3222 H  H    . TYR A 1 208 ? 13.82300  -24.18800 30.13500 1.000 61.90000  ? 208 TYR A H    1 
ATOM   3223 H  HA   . TYR A 1 208 ? 11.32400  -25.12000 30.51400 1.000 66.24000  ? 208 TYR A HA   1 
ATOM   3224 H  HB2  . TYR A 1 208 ? 10.97900  -23.07000 29.41000 1.000 63.75000  ? 208 TYR A HB2  1 
ATOM   3225 H  HB3  . TYR A 1 208 ? 11.91200  -23.56800 28.22400 1.000 63.75000  ? 208 TYR A HB3  1 
ATOM   3226 H  HD1  . TYR A 1 208 ? 8.82700   -24.36100 29.79900 1.000 67.15000  ? 208 TYR A HD1  1 
ATOM   3227 H  HD2  . TYR A 1 208 ? 10.95100  -24.80400 26.44200 1.000 70.12000  ? 208 TYR A HD2  1 
ATOM   3228 H  HE1  . TYR A 1 208 ? 7.00200   -25.32600 28.77700 1.000 70.74000  ? 208 TYR A HE1  1 
ATOM   3229 H  HE2  . TYR A 1 208 ? 9.12400   -25.76800 25.41200 1.000 72.12000  ? 208 TYR A HE2  1 
ATOM   3230 H  HH   . TYR A 1 208 ? 6.15900   -26.26800 26.93200 1.000 76.37000  ? 208 TYR A HH   1 
ATOM   3231 N  N    . MET A 1 209 ? 11.69700  -27.08400 29.07800 1.000 51.09560  ? 209 MET A N    1 
ATOM   3232 C  CA   . MET A 1 209 ? 12.04100  -28.34700 28.43300 1.000 52.76685  ? 209 MET A CA   1 
ATOM   3233 C  C    . MET A 1 209 ? 11.01900  -28.60800 27.33500 1.000 57.80167  ? 209 MET A C    1 
ATOM   3234 O  O    . MET A 1 209 ? 9.85000   -28.88400 27.62400 1.000 56.18042  ? 209 MET A O    1 
ATOM   3235 C  CB   . MET A 1 209 ? 12.05300  -29.48200 29.45700 1.000 54.16965  ? 209 MET A CB   1 
ATOM   3236 C  CG   . MET A 1 209 ? 12.65000  -30.81200 28.99100 1.000 64.74197  ? 209 MET A CG   1 
ATOM   3237 S  SD   . MET A 1 209 ? 14.01500  -30.70400 27.82100 1.000 67.89761  ? 209 MET A SD   1 
ATOM   3238 C  CE   . MET A 1 209 ? 14.15200  -32.41200 27.29800 1.000 72.89295  ? 209 MET A CE   1 
ATOM   3239 H  H    . MET A 1 209 ? 10.92500  -27.10000 29.45500 1.000 61.43000  ? 209 MET A H    1 
ATOM   3240 H  HA   . MET A 1 209 ? 12.92400  -28.28400 28.03600 1.000 63.43000  ? 209 MET A HA   1 
ATOM   3241 H  HB2  . MET A 1 209 ? 12.57000  -29.19000 30.22400 1.000 65.12000  ? 209 MET A HB2  1 
ATOM   3242 H  HB3  . MET A 1 209 ? 11.13600  -29.65800 29.72200 1.000 65.12000  ? 209 MET A HB3  1 
ATOM   3243 H  HG2  . MET A 1 209 ? 12.97900  -31.28600 29.77100 1.000 77.80000  ? 209 MET A HG2  1 
ATOM   3244 H  HG3  . MET A 1 209 ? 11.94700  -31.32600 28.56300 1.000 77.80000  ? 209 MET A HG3  1 
ATOM   3245 H  HE1  . MET A 1 209 ? 14.86900  -32.48700 26.64900 1.000 87.58000  ? 209 MET A HE1  1 
ATOM   3246 H  HE2  . MET A 1 209 ? 14.34700  -32.96500 28.07100 1.000 87.58000  ? 209 MET A HE2  1 
ATOM   3247 H  HE3  . MET A 1 209 ? 13.31300  -32.68800 26.89700 1.000 87.58000  ? 209 MET A HE3  1 
ATOM   3248 N  N    . GLY A 1 210 ? 11.45400  -28.51700 26.08100 1.000 56.41466  ? 210 GLY A N    1 
ATOM   3249 C  CA   . GLY A 1 210 ? 10.56900  -28.79400 24.96700 1.000 58.79916  ? 210 GLY A CA   1 
ATOM   3250 C  C    . GLY A 1 210 ? 11.04400  -28.21200 23.65200 1.000 60.14932  ? 210 GLY A C    1 
ATOM   3251 O  O    . GLY A 1 210 ? 10.86000  -28.82300 22.59500 1.000 62.80227  ? 210 GLY A O    1 
ATOM   3252 H  H    . GLY A 1 210 ? 12.25400  -28.29600 25.85500 1.000 67.81000  ? 210 GLY A H    1 
ATOM   3253 H  HA2  . GLY A 1 210 ? 10.48900  -29.75500 24.85900 1.000 70.67000  ? 210 GLY A HA2  1 
ATOM   3254 H  HA3  . GLY A 1 210 ? 9.69300   -28.42400 25.16000 1.000 70.67000  ? 210 GLY A HA3  1 
ATOM   3255 N  N    . THR A 1 211 ? 11.65000  -27.02900 23.70100 1.000 56.23306  ? 211 THR A N    1 
ATOM   3256 C  CA   . THR A 1 211 ? 12.12200  -26.36300 22.49700 1.000 60.72833  ? 211 THR A CA   1 
ATOM   3257 C  C    . THR A 1 211 ? 13.37800  -25.57400 22.83100 1.000 56.61205  ? 211 THR A C    1 
ATOM   3258 O  O    . THR A 1 211 ? 13.53800  -25.07900 23.95000 1.000 53.38798  ? 211 THR A O    1 
ATOM   3259 C  CB   . THR A 1 211 ? 11.05300  -25.43200 21.91100 1.000 62.34695  ? 211 THR A CB   1 
ATOM   3260 O  OG1  . THR A 1 211 ? 11.60800  -24.68500 20.82200 1.000 67.00014  ? 211 THR A OG1  1 
ATOM   3261 C  CG2  . THR A 1 211 ? 10.53800  -24.47000 22.97200 1.000 63.53657  ? 211 THR A CG2  1 
ATOM   3262 H  H    . THR A 1 211 ? 11.80000  -26.59100 24.42600 1.000 67.59000  ? 211 THR A H    1 
ATOM   3263 H  HA   . THR A 1 211 ? 12.34700  -27.02600 21.82700 1.000 72.99000  ? 211 THR A HA   1 
ATOM   3264 H  HB   . THR A 1 211 ? 10.30600  -25.96200 21.59100 1.000 74.93000  ? 211 THR A HB   1 
ATOM   3265 H  HG1  . THR A 1 211 ? 11.03200  -24.15700 20.51200 1.000 80.51000  ? 211 THR A HG1  1 
ATOM   3266 H  HG21 . THR A 1 211 ? 9.96000   -23.80600 22.56500 1.000 76.36000  ? 211 THR A HG21 1 
ATOM   3267 H  HG22 . THR A 1 211 ? 10.03400  -24.95600 23.64400 1.000 76.36000  ? 211 THR A HG22 1 
ATOM   3268 H  HG23 . THR A 1 211 ? 11.28200  -24.01900 23.40000 1.000 76.36000  ? 211 THR A HG23 1 
ATOM   3269 N  N    . LEU A 1 212 ? 14.26900  -25.46500 21.84700 1.000 53.68275  ? 212 LEU A N    1 
ATOM   3270 C  CA   . LEU A 1 212 ? 15.51500  -24.73200 22.02200 1.000 54.06701  ? 212 LEU A CA   1 
ATOM   3271 C  C    . LEU A 1 212 ? 15.39800  -23.26000 21.65500 1.000 53.51957  ? 212 LEU A C    1 
ATOM   3272 O  O    . LEU A 1 212 ? 16.21600  -22.45400 22.11600 1.000 55.59614  ? 212 LEU A O    1 
ATOM   3273 C  CB   . LEU A 1 212 ? 16.62400  -25.36500 21.17500 1.000 53.02741  ? 212 LEU A CB   1 
ATOM   3274 C  CG   . LEU A 1 212 ? 16.88200  -26.86100 21.35800 1.000 50.55606  ? 212 LEU A CG   1 
ATOM   3275 C  CD1  . LEU A 1 212 ? 17.87600  -27.34600 20.31200 1.000 52.09046  ? 212 LEU A CD1  1 
ATOM   3276 C  CD2  . LEU A 1 212 ? 17.38900  -27.16700 22.76100 1.000 53.16690  ? 212 LEU A CD2  1 
ATOM   3277 H  H    . LEU A 1 212 ? 14.17300  -25.80900 21.06500 1.000 64.53000  ? 212 LEU A H    1 
ATOM   3278 H  HA   . LEU A 1 212 ? 15.77600  -24.79000 22.95500 1.000 65.00000  ? 212 LEU A HA   1 
ATOM   3279 H  HB2  . LEU A 1 212 ? 16.39800  -25.23100 20.24200 1.000 63.75000  ? 212 LEU A HB2  1 
ATOM   3280 H  HB3  . LEU A 1 212 ? 17.45400  -24.90900 21.38500 1.000 63.75000  ? 212 LEU A HB3  1 
ATOM   3281 H  HG   . LEU A 1 212 ? 16.04800  -27.34100 21.24200 1.000 60.78000  ? 212 LEU A HG   1 
ATOM   3282 H  HD11 . LEU A 1 212 ? 18.03800  -28.29300 20.44500 1.000 62.62000  ? 212 LEU A HD11 1 
ATOM   3283 H  HD12 . LEU A 1 212 ? 17.50400  -27.19500 19.42900 1.000 62.62000  ? 212 LEU A HD12 1 
ATOM   3284 H  HD13 . LEU A 1 212 ? 18.70500  -26.85200 20.41100 1.000 62.62000  ? 212 LEU A HD13 1 
ATOM   3285 H  HD21 . LEU A 1 212 ? 17.58500  -28.11500 22.82700 1.000 63.91000  ? 212 LEU A HD21 1 
ATOM   3286 H  HD22 . LEU A 1 212 ? 18.19300  -26.65100 22.92600 1.000 63.91000  ? 212 LEU A HD22 1 
ATOM   3287 H  HD23 . LEU A 1 212 ? 16.70300  -26.92600 23.40400 1.000 63.91000  ? 212 LEU A HD23 1 
ATOM   3288 N  N    . SER A 1 213 ? 14.40500  -22.89000 20.85000 1.000 57.91747  ? 213 SER A N    1 
ATOM   3289 C  CA   . SER A 1 213 ? 14.29600  -21.53800 20.31600 1.000 55.96987  ? 213 SER A CA   1 
ATOM   3290 C  C    . SER A 1 213 ? 13.52300  -20.65700 21.28800 1.000 56.09620  ? 213 SER A C    1 
ATOM   3291 O  O    . SER A 1 213 ? 12.35400  -20.92800 21.58700 1.000 54.07227  ? 213 SER A O    1 
ATOM   3292 C  CB   . SER A 1 213 ? 13.60700  -21.55400 18.95100 1.000 58.87285  ? 213 SER A CB   1 
ATOM   3293 O  OG   . SER A 1 213 ? 13.26700  -20.24100 18.53700 1.000 56.91209  ? 213 SER A OG   1 
ATOM   3294 H  H    . SER A 1 213 ? 13.77300  -23.41400 20.59600 1.000 69.62000  ? 213 SER A H    1 
ATOM   3295 H  HA   . SER A 1 213 ? 15.18600  -21.16700 20.21200 1.000 67.28000  ? 213 SER A HA   1 
ATOM   3296 H  HB2  . SER A 1 213 ? 14.21000  -21.94400 18.29800 1.000 70.76000  ? 213 SER A HB2  1 
ATOM   3297 H  HB3  . SER A 1 213 ? 12.79800  -22.08500 19.01300 1.000 70.76000  ? 213 SER A HB3  1 
ATOM   3298 H  HG   . SER A 1 213 ? 13.95600  -19.76200 18.50800 1.000 68.41000  ? 213 SER A HG   1 
ATOM   3299 N  N    . TYR A 1 214 ? 14.17700  -19.60100 21.77600 1.000 60.82045  ? 214 TYR A N    1 
ATOM   3300 C  CA   . TYR A 1 214 ? 13.49800  -18.64100 22.64100 1.000 56.83576  ? 214 TYR A CA   1 
ATOM   3301 C  C    . TYR A 1 214 ? 12.41400  -17.89000 21.87700 1.000 59.70189  ? 214 TYR A C    1 
ATOM   3302 O  O    . TYR A 1 214 ? 11.36000  -17.56900 22.43900 1.000 62.27326  ? 214 TYR A O    1 
ATOM   3303 C  CB   . TYR A 1 214 ? 14.52200  -17.66900 23.23200 1.000 54.94606  ? 214 TYR A CB   1 
ATOM   3304 C  CG   . TYR A 1 214 ? 14.04300  -16.86300 24.42600 1.000 56.61995  ? 214 TYR A CG   1 
ATOM   3305 C  CD1  . TYR A 1 214 ? 13.08900  -17.36500 25.30300 1.000 56.70154  ? 214 TYR A CD1  1 
ATOM   3306 C  CD2  . TYR A 1 214 ? 14.56300  -15.60100 24.68000 1.000 55.61983  ? 214 TYR A CD2  1 
ATOM   3307 C  CE1  . TYR A 1 214 ? 12.66000  -16.62800 26.39200 1.000 56.80681  ? 214 TYR A CE1  1 
ATOM   3308 C  CE2  . TYR A 1 214 ? 14.14100  -14.85800 25.76500 1.000 56.28306  ? 214 TYR A CE2  1 
ATOM   3309 C  CZ   . TYR A 1 214 ? 13.19000  -15.37600 26.61800 1.000 60.11247  ? 214 TYR A CZ   1 
ATOM   3310 O  OH   . TYR A 1 214 ? 12.76900  -14.63800 27.70000 1.000 60.78624  ? 214 TYR A OH   1 
ATOM   3311 H  H    . TYR A 1 214 ? 15.00400  -19.42100 21.62300 1.000 73.10000  ? 214 TYR A H    1 
ATOM   3312 H  HA   . TYR A 1 214 ? 13.07400  -19.11300 23.37400 1.000 68.31000  ? 214 TYR A HA   1 
ATOM   3313 H  HB2  . TYR A 1 214 ? 15.29600  -18.17800 23.51900 1.000 66.05000  ? 214 TYR A HB2  1 
ATOM   3314 H  HB3  . TYR A 1 214 ? 14.77700  -17.03800 22.54100 1.000 66.05000  ? 214 TYR A HB3  1 
ATOM   3315 H  HD1  . TYR A 1 214 ? 12.73200  -18.21100 25.15500 1.000 68.16000  ? 214 TYR A HD1  1 
ATOM   3316 H  HD2  . TYR A 1 214 ? 15.20700  -15.24900 24.10900 1.000 66.86000  ? 214 TYR A HD2  1 
ATOM   3317 H  HE1  . TYR A 1 214 ? 12.01800  -16.97500 26.96800 1.000 68.28000  ? 214 TYR A HE1  1 
ATOM   3318 H  HE2  . TYR A 1 214 ? 14.49700  -14.01300 25.92000 1.000 67.65000  ? 214 TYR A HE2  1 
ATOM   3319 H  HH   . TYR A 1 214 ? 13.18400  -13.90900 27.72900 1.000 73.06000  ? 214 TYR A HH   1 
ATOM   3320 N  N    . GLU A 1 215 ? 12.64800  -17.60900 20.59300 1.000 64.05505  ? 215 GLU A N    1 
ATOM   3321 C  CA   . GLU A 1 215 ? 11.64500  -16.90900 19.79600 1.000 65.38416  ? 215 GLU A CA   1 
ATOM   3322 C  C    . GLU A 1 215 ? 10.38700  -17.75700 19.64000 1.000 65.11307  ? 215 GLU A C    1 
ATOM   3323 O  O    . GLU A 1 215 ? 9.26900   -17.27300 19.84900 1.000 65.35257  ? 215 GLU A O    1 
ATOM   3324 C  CB   . GLU A 1 215 ? 12.22200  -16.53900 18.42900 1.000 65.65261  ? 215 GLU A CB   1 
ATOM   3325 C  CG   . GLU A 1 215 ? 13.46200  -15.65200 18.49100 1.000 71.65859  ? 215 GLU A CG   1 
ATOM   3326 C  CD   . GLU A 1 215 ? 13.27900  -14.44800 19.39900 1.000 84.40486  ? 215 GLU A CD   1 
ATOM   3327 O  OE1  . GLU A 1 215 ? 12.42400  -13.59100 19.08600 1.000 83.24946  ? 215 GLU A OE1  1 
ATOM   3328 O  OE2  . GLU A 1 215 ? 13.98800  -14.36300 20.42600 1.000 79.87800  ? 215 GLU A OE2  1 
ATOM   3329 H  H    . GLU A 1 215 ? 13.36900  -17.80900 20.16800 1.000 76.98000  ? 215 GLU A H    1 
ATOM   3330 H  HA   . GLU A 1 215 ? 11.40100  -16.08700 20.24900 1.000 78.57000  ? 215 GLU A HA   1 
ATOM   3331 H  HB2  . GLU A 1 215 ? 12.46800  -17.35500 17.96500 1.000 78.90000  ? 215 GLU A HB2  1 
ATOM   3332 H  HB3  . GLU A 1 215 ? 11.54500  -16.06200 17.92500 1.000 78.90000  ? 215 GLU A HB3  1 
ATOM   3333 H  HG2  . GLU A 1 215 ? 14.20600  -16.17300 18.83000 1.000 86.10000  ? 215 GLU A HG2  1 
ATOM   3334 H  HG3  . GLU A 1 215 ? 13.66300  -15.32700 17.59900 1.000 86.10000  ? 215 GLU A HG3  1 
ATOM   3335 N  N    . GLN A 1 216 ? 10.55100  -19.03100 19.27300 1.000 63.49972  ? 216 GLN A N    1 
ATOM   3336 C  CA   . GLN A 1 216 ? 9.39400   -19.91500 19.15800 1.000 67.41071  ? 216 GLN A CA   1 
ATOM   3337 C  C    . GLN A 1 216 ? 8.62400   -19.99500 20.47000 1.000 67.67127  ? 216 GLN A C    1 
ATOM   3338 O  O    . GLN A 1 216 ? 7.39300   -20.11000 20.46100 1.000 66.48166  ? 216 GLN A O    1 
ATOM   3339 C  CB   . GLN A 1 216 ? 9.84100   -21.30900 18.71700 1.000 68.88457  ? 216 GLN A CB   1 
ATOM   3340 C  CG   . GLN A 1 216 ? 8.71300   -22.21000 18.21900 1.000 72.17444  ? 216 GLN A CG   1 
ATOM   3341 C  CD   . GLN A 1 216 ? 7.90300   -21.58200 17.09900 1.000 79.01737  ? 216 GLN A CD   1 
ATOM   3342 O  OE1  . GLN A 1 216 ? 8.45100   -20.92900 16.21000 1.000 79.23582  ? 216 GLN A OE1  1 
ATOM   3343 N  NE2  . GLN A 1 216 ? 6.59000   -21.77800 17.13900 1.000 77.06713  ? 216 GLN A NE2  1 
ATOM   3344 H  H    . GLN A 1 216 ? 11.30600  -19.39900 19.08900 1.000 76.31000  ? 216 GLN A H    1 
ATOM   3345 H  HA   . GLN A 1 216 ? 8.79700   -19.56400 18.47900 1.000 81.01000  ? 216 GLN A HA   1 
ATOM   3346 H  HB2  . GLN A 1 216 ? 10.48000  -21.21400 17.99300 1.000 82.78000  ? 216 GLN A HB2  1 
ATOM   3347 H  HB3  . GLN A 1 216 ? 10.25800  -21.75300 19.47100 1.000 82.78000  ? 216 GLN A HB3  1 
ATOM   3348 H  HG2  . GLN A 1 216 ? 9.09400   -23.03700 17.88500 1.000 86.72000  ? 216 GLN A HG2  1 
ATOM   3349 H  HG3  . GLN A 1 216 ? 8.11000   -22.39600 18.95600 1.000 86.72000  ? 216 GLN A HG3  1 
ATOM   3350 H  HE21 . GLN A 1 216 ? 6.24300   -22.23900 17.77600 1.000 92.59000  ? 216 GLN A HE21 1 
ATOM   3351 H  HE22 . GLN A 1 216 ? 6.08700   -21.44300 16.52700 1.000 92.59000  ? 216 GLN A HE22 1 
ATOM   3352 N  N    . PHE A 1 217 ? 9.32700   -19.94100 21.60400 1.000 66.97908  ? 217 PHE A N    1 
ATOM   3353 C  CA   . PHE A 1 217 ? 8.64800   -19.91100 22.89700 1.000 63.61552  ? 217 PHE A CA   1 
ATOM   3354 C  C    . PHE A 1 217 ? 7.71500   -18.70800 22.99400 1.000 63.31812  ? 217 PHE A C    1 
ATOM   3355 O  O    . PHE A 1 217 ? 6.59100   -18.82200 23.49600 1.000 64.40246  ? 217 PHE A O    1 
ATOM   3356 C  CB   . PHE A 1 217 ? 9.68500   -19.88800 24.02300 1.000 59.07024  ? 217 PHE A CB   1 
ATOM   3357 C  CG   . PHE A 1 217 ? 9.16800   -20.37400 25.35500 1.000 63.39181  ? 217 PHE A CG   1 
ATOM   3358 C  CD1  . PHE A 1 217 ? 8.41700   -21.53500 25.45200 1.000 62.35221  ? 217 PHE A CD1  1 
ATOM   3359 C  CD2  . PHE A 1 217 ? 9.45400   -19.67200 26.51400 1.000 61.02837  ? 217 PHE A CD2  1 
ATOM   3360 C  CE1  . PHE A 1 217 ? 7.95300   -21.97600 26.67900 1.000 66.72642  ? 217 PHE A CE1  1 
ATOM   3361 C  CE2  . PHE A 1 217 ? 8.99300   -20.11000 27.74200 1.000 57.67797  ? 217 PHE A CE2  1 
ATOM   3362 C  CZ   . PHE A 1 217 ? 8.24300   -21.26300 27.82400 1.000 56.76733  ? 217 PHE A CZ   1 
ATOM   3363 H  H    . PHE A 1 217 ? 10.18500  -19.92100 21.65100 1.000 80.49000  ? 217 PHE A H    1 
ATOM   3364 H  HA   . PHE A 1 217 ? 8.11200   -20.71300 22.99800 1.000 76.45000  ? 217 PHE A HA   1 
ATOM   3365 H  HB2  . PHE A 1 217 ? 10.42800  -20.45800 23.77100 1.000 71.00000  ? 217 PHE A HB2  1 
ATOM   3366 H  HB3  . PHE A 1 217 ? 9.99200   -18.97600 24.14200 1.000 71.00000  ? 217 PHE A HB3  1 
ATOM   3367 H  HD1  . PHE A 1 217 ? 8.22400   -22.02300 24.68500 1.000 74.93000  ? 217 PHE A HD1  1 
ATOM   3368 H  HD2  . PHE A 1 217 ? 9.96400   -18.89600 26.46700 1.000 73.34000  ? 217 PHE A HD2  1 
ATOM   3369 H  HE1  . PHE A 1 217 ? 7.44600   -22.75400 26.73100 1.000 80.19000  ? 217 PHE A HE1  1 
ATOM   3370 H  HE2  . PHE A 1 217 ? 9.18900   -19.62700 28.51200 1.000 69.33000  ? 217 PHE A HE2  1 
ATOM   3371 H  HZ   . PHE A 1 217 ? 7.93200   -21.55900 28.64900 1.000 68.23000  ? 217 PHE A HZ   1 
ATOM   3372 N  N    . LYS A 1 218 ? 8.16200   -17.54700 22.50700 1.000 58.75968  ? 218 LYS A N    1 
ATOM   3373 C  CA   . LYS A 1 218 ? 7.31800   -16.35800 22.54000 1.000 61.73109  ? 218 LYS A CA   1 
ATOM   3374 C  C    . LYS A 1 218 ? 6.13500   -16.49100 21.58700 1.000 66.94487  ? 218 LYS A C    1 
ATOM   3375 O  O    . LYS A 1 218 ? 5.02700   -16.04000 21.89900 1.000 67.93972  ? 218 LYS A O    1 
ATOM   3376 C  CB   . LYS A 1 218 ? 8.14400   -15.11900 22.19200 1.000 64.26034  ? 218 LYS A CB   1 
ATOM   3377 C  CG   . LYS A 1 218 ? 9.19300   -14.75400 23.23000 1.000 61.99164  ? 218 LYS A CG   1 
ATOM   3378 C  CD   . LYS A 1 218 ? 10.18300  -13.73800 22.68200 1.000 65.01043  ? 218 LYS A CD   1 
ATOM   3379 C  CE   . LYS A 1 218 ? 11.25200  -13.39100 23.70400 1.000 65.71577  ? 218 LYS A CE   1 
ATOM   3380 N  NZ   . LYS A 1 218 ? 12.35200  -12.58400 23.10800 1.000 70.73743  ? 218 LYS A NZ   1 
ATOM   3381 H  H    . LYS A 1 218 ? 8.93900   -17.42600 22.15800 1.000 70.62000  ? 218 LYS A H    1 
ATOM   3382 H  HA   . LYS A 1 218 ? 6.97100   -16.24800 23.43900 1.000 74.19000  ? 218 LYS A HA   1 
ATOM   3383 H  HB2  . LYS A 1 218 ? 8.60500   -15.28000 21.35300 1.000 77.23000  ? 218 LYS A HB2  1 
ATOM   3384 H  HB3  . LYS A 1 218 ? 7.54500   -14.36200 22.10100 1.000 77.23000  ? 218 LYS A HB3  1 
ATOM   3385 H  HG2  . LYS A 1 218 ? 8.75700   -14.36800 24.00600 1.000 74.50000  ? 218 LYS A HG2  1 
ATOM   3386 H  HG3  . LYS A 1 218 ? 9.68300   -15.55000 23.48700 1.000 74.50000  ? 218 LYS A HG3  1 
ATOM   3387 H  HD2  . LYS A 1 218 ? 10.61900  -14.10700 21.89800 1.000 78.12000  ? 218 LYS A HD2  1 
ATOM   3388 H  HD3  . LYS A 1 218 ? 9.71000   -12.92400 22.44700 1.000 78.12000  ? 218 LYS A HD3  1 
ATOM   3389 H  HE2  . LYS A 1 218 ? 10.85100  -12.87600 24.42200 1.000 78.97000  ? 218 LYS A HE2  1 
ATOM   3390 H  HE3  . LYS A 1 218 ? 11.63400  -14.21000 24.05700 1.000 78.97000  ? 218 LYS A HE3  1 
ATOM   3391 H  HZ1  . LYS A 1 218 ? 12.95400  -12.38200 23.73200 1.000 85.00000  ? 218 LYS A HZ1  1 
ATOM   3392 H  HZ2  . LYS A 1 218 ? 12.75100  -13.04400 22.46000 1.000 85.00000  ? 218 LYS A HZ2  1 
ATOM   3393 H  HZ3  . LYS A 1 218 ? 12.02500  -11.82900 22.76800 1.000 85.00000  ? 218 LYS A HZ3  1 
ATOM   3394 N  N    . LYS A 1 219 ? 6.35100   -17.10400 20.42000 1.000 66.42112  ? 219 LYS A N    1 
ATOM   3395 C  CA   . LYS A 1 219 ? 5.26400   -17.25700 19.45700 1.000 71.54542  ? 219 LYS A CA   1 
ATOM   3396 C  C    . LYS A 1 219 ? 4.26600   -18.31500 19.91100 1.000 72.31920  ? 219 LYS A C    1 
ATOM   3397 O  O    . LYS A 1 219 ? 3.05100   -18.11200 19.81300 1.000 72.02443  ? 219 LYS A O    1 
ATOM   3398 C  CB   . LYS A 1 219 ? 5.82600   -17.61100 18.07900 1.000 72.59028  ? 219 LYS A CB   1 
ATOM   3399 C  CG   . LYS A 1 219 ? 7.04600   -16.79700 17.67300 1.000 79.08580  ? 219 LYS A CG   1 
ATOM   3400 C  CD   . LYS A 1 219 ? 7.18400   -16.70100 16.15900 1.000 91.65836  ? 219 LYS A CD   1 
ATOM   3401 C  CE   . LYS A 1 219 ? 8.60100   -16.31700 15.74700 1.000 95.99309  ? 219 LYS A CE   1 
ATOM   3402 N  NZ   . LYS A 1 219 ? 9.03500   -17.01900 14.50500 1.000 105.18366 ? 219 LYS A NZ   1 
ATOM   3403 H  H    . LYS A 1 219 ? 7.10300   -17.43400 20.16800 1.000 79.82000  ? 219 LYS A H    1 
ATOM   3404 H  HA   . LYS A 1 219 ? 4.79600   -16.41100 19.38300 1.000 85.97000  ? 219 LYS A HA   1 
ATOM   3405 H  HB2  . LYS A 1 219 ? 6.08400   -18.54600 18.08100 1.000 87.22000  ? 219 LYS A HB2  1 
ATOM   3406 H  HB3  . LYS A 1 219 ? 5.13600   -17.45900 17.41500 1.000 87.22000  ? 219 LYS A HB3  1 
ATOM   3407 H  HG2  . LYS A 1 219 ? 6.96400   -15.89900 18.02900 1.000 95.02000  ? 219 LYS A HG2  1 
ATOM   3408 H  HG3  . LYS A 1 219 ? 7.84500   -17.22100 18.02400 1.000 95.02000  ? 219 LYS A HG3  1 
ATOM   3409 H  HD2  . LYS A 1 219 ? 6.97300   -17.56000 15.76200 1.000 110.10000 ? 219 LYS A HD2  1 
ATOM   3410 H  HD3  . LYS A 1 219 ? 6.57600   -16.02300 15.82400 1.000 110.10000 ? 219 LYS A HD3  1 
ATOM   3411 H  HE2  . LYS A 1 219 ? 8.63800   -15.36200 15.58200 1.000 115.31000 ? 219 LYS A HE2  1 
ATOM   3412 H  HE3  . LYS A 1 219 ? 9.21500   -16.55600 16.45900 1.000 115.31000 ? 219 LYS A HE3  1 
ATOM   3413 H  HZ1  . LYS A 1 219 ? 9.86400   -16.77700 14.29300 1.000 126.34000 ? 219 LYS A HZ1  1 
ATOM   3414 H  HZ2  . LYS A 1 219 ? 9.01300   -17.90000 14.63000 1.000 126.34000 ? 219 LYS A HZ2  1 
ATOM   3415 H  HZ3  . LYS A 1 219 ? 8.49200   -16.81000 13.83200 1.000 126.34000 ? 219 LYS A HZ3  1 
ATOM   3416 N  N    . GLY A 1 220 ? 4.75800   -19.45100 20.40300 1.000 69.69257  ? 220 GLY A N    1 
ATOM   3417 C  CA   . GLY A 1 220 ? 3.88900   -20.51100 20.87600 1.000 70.42687  ? 220 GLY A CA   1 
ATOM   3418 C  C    . GLY A 1 220 ? 4.39100   -21.89500 20.52300 1.000 70.56636  ? 220 GLY A C    1 
ATOM   3419 O  O    . GLY A 1 220 ? 4.94100   -22.10500 19.43900 1.000 71.14537  ? 220 GLY A O    1 
ATOM   3420 H  H    . GLY A 1 220 ? 5.59600   -19.62800 20.47200 1.000 83.74000  ? 220 GLY A H    1 
ATOM   3421 H  HA2  . GLY A 1 220 ? 3.81400   -20.45300 21.84200 1.000 84.62000  ? 220 GLY A HA2  1 
ATOM   3422 H  HA3  . GLY A 1 220 ? 3.00900   -20.39900 20.48400 1.000 84.62000  ? 220 GLY A HA3  1 
ATOM   3423 N  N    . VAL A 1 221 ? 4.20700   -22.85000 21.43500 1.000 74.29049  ? 221 VAL A N    1 
ATOM   3424 C  CA   . VAL A 1 221 ? 4.62900   -24.22900 21.23200 1.000 70.46634  ? 221 VAL A CA   1 
ATOM   3425 C  C    . VAL A 1 221 ? 3.44600   -25.14400 21.51200 1.000 73.63514  ? 221 VAL A C    1 
ATOM   3426 O  O    . VAL A 1 221 ? 2.61600   -24.87200 22.38500 1.000 74.40103  ? 221 VAL A O    1 
ATOM   3427 C  CB   . VAL A 1 221 ? 5.83100   -24.60500 22.12600 1.000 71.42435  ? 221 VAL A CB   1 
ATOM   3428 C  CG1  . VAL A 1 221 ? 6.91100   -23.53800 22.04000 1.000 70.50319  ? 221 VAL A CG1  1 
ATOM   3429 C  CG2  . VAL A 1 221 ? 5.38600   -24.80500 23.56800 1.000 70.76638  ? 221 VAL A CG2  1 
ATOM   3430 H  H    . VAL A 1 221 ? 3.83200   -22.71600 22.19700 1.000 89.26000  ? 221 VAL A H    1 
ATOM   3431 H  HA   . VAL A 1 221 ? 4.89500   -24.34700 20.30700 1.000 84.67000  ? 221 VAL A HA   1 
ATOM   3432 H  HB   . VAL A 1 221 ? 6.20700   -25.44200 21.81100 1.000 85.82000  ? 221 VAL A HB   1 
ATOM   3433 H  HG11 . VAL A 1 221 ? 7.69600   -23.84400 22.52100 1.000 84.71000  ? 221 VAL A HG11 1 
ATOM   3434 H  HG12 . VAL A 1 221 ? 7.13200   -23.38800 21.10700 1.000 84.71000  ? 221 VAL A HG12 1 
ATOM   3435 H  HG13 . VAL A 1 221 ? 6.57800   -22.71900 22.43700 1.000 84.71000  ? 221 VAL A HG13 1 
ATOM   3436 H  HG21 . VAL A 1 221 ? 6.16100   -24.75000 24.14900 1.000 85.03000  ? 221 VAL A HG21 1 
ATOM   3437 H  HG22 . VAL A 1 221 ? 4.74800   -24.11300 23.80100 1.000 85.03000  ? 221 VAL A HG22 1 
ATOM   3438 H  HG23 . VAL A 1 221 ? 4.97200   -25.67800 23.65300 1.000 85.03000  ? 221 VAL A HG23 1 
ATOM   3439 N  N    . GLN A 1 222 ? 3.37800   -26.24200 20.76500 1.000 74.95109  ? 222 GLN A N    1 
ATOM   3440 C  CA   . GLN A 1 222 ? 2.26000   -27.16700 20.87000 1.000 76.43022  ? 222 GLN A CA   1 
ATOM   3441 C  C    . GLN A 1 222 ? 2.48700   -28.14300 22.01900 1.000 73.00875  ? 222 GLN A C    1 
ATOM   3442 O  O    . GLN A 1 222 ? 3.56800   -28.72600 22.14600 1.000 72.44290  ? 222 GLN A O    1 
ATOM   3443 C  CB   . GLN A 1 222 ? 2.08000   -27.92900 19.55800 1.000 82.85730  ? 222 GLN A CB   1 
ATOM   3444 C  CG   . GLN A 1 222 ? 2.01700   -27.04200 18.32000 1.000 82.49410  ? 222 GLN A CG   1 
ATOM   3445 C  CD   . GLN A 1 222 ? 1.23300   -25.76300 18.55100 1.000 88.77643  ? 222 GLN A CD   1 
ATOM   3446 O  OE1  . GLN A 1 222 ? 0.06200   -25.79900 18.93200 1.000 86.44194  ? 222 GLN A OE1  1 
ATOM   3447 N  NE2  . GLN A 1 222 ? 1.87600   -24.62300 18.32100 1.000 84.97071  ? 222 GLN A NE2  1 
ATOM   3448 H  H    . GLN A 1 222 ? 3.97100   -26.47300 20.18600 1.000 90.06000  ? 222 GLN A H    1 
ATOM   3449 H  HA   . GLN A 1 222 ? 1.44700   -26.67000 21.05200 1.000 91.83000  ? 222 GLN A HA   1 
ATOM   3450 H  HB2  . GLN A 1 222 ? 2.83000   -28.53500 19.44700 1.000 99.54000  ? 222 GLN A HB2  1 
ATOM   3451 H  HB3  . GLN A 1 222 ? 1.25100   -28.43100 19.60200 1.000 99.54000  ? 222 GLN A HB3  1 
ATOM   3452 H  HG2  . GLN A 1 222 ? 2.92000   -26.79700 18.06100 1.000 99.11000  ? 222 GLN A HG2  1 
ATOM   3453 H  HG3  . GLN A 1 222 ? 1.58700   -27.53100 17.60200 1.000 99.11000  ? 222 GLN A HG3  1 
ATOM   3454 H  HE21 . GLN A 1 222 ? 2.69400   -24.63700 18.05600 1.000 102.08000 ? 222 GLN A HE21 1 
ATOM   3455 H  HE22 . GLN A 1 222 ? 1.47500   -23.87100 18.43800 1.000 102.08000 ? 222 GLN A HE22 1 
ATOM   3456 N  N    . ILE A 1 223 ? 1.46700   -28.31400 22.85800 1.000 72.54028  ? 223 ILE A N    1 
ATOM   3457 C  CA   . ILE A 1 223 ? 1.52500   -29.28400 23.95500 1.000 73.42459  ? 223 ILE A CA   1 
ATOM   3458 C  C    . ILE A 1 223 ? 0.19000   -29.99400 24.06000 1.000 74.54315  ? 223 ILE A C    1 
ATOM   3459 O  O    . ILE A 1 223 ? -0.86000  -29.45400 23.68800 1.000 77.13293  ? 223 ILE A O    1 
ATOM   3460 C  CB   . ILE A 1 223 ? 1.86600   -28.61200 25.30700 1.000 72.02179  ? 223 ILE A CB   1 
ATOM   3461 C  CG1  . ILE A 1 223 ? 0.66200   -27.84200 25.86900 1.000 74.70896  ? 223 ILE A CG1  1 
ATOM   3462 C  CG2  . ILE A 1 223 ? 3.07400   -27.69200 25.14700 1.000 69.33200  ? 223 ILE A CG2  1 
ATOM   3463 C  CD1  . ILE A 1 223 ? 0.89200   -27.25000 27.25400 1.000 70.52951  ? 223 ILE A CD1  1 
ATOM   3464 H  H    . ILE A 1 223 ? 0.72600   -27.88000 22.81400 1.000 87.16000  ? 223 ILE A H    1 
ATOM   3465 H  HA   . ILE A 1 223 ? 2.21000   -29.94300 23.76600 1.000 88.22000  ? 223 ILE A HA   1 
ATOM   3466 H  HB   . ILE A 1 223 ? 2.08700   -29.31100 25.94200 1.000 86.54000  ? 223 ILE A HB   1 
ATOM   3467 H  HG12 . ILE A 1 223 ? 0.45400   -27.11000 25.26700 1.000 89.76000  ? 223 ILE A HG12 1 
ATOM   3468 H  HG13 . ILE A 1 223 ? -0.09300  -28.44700 25.92900 1.000 89.76000  ? 223 ILE A HG13 1 
ATOM   3469 H  HG21 . ILE A 1 223 ? 3.28600   -27.29700 26.00800 1.000 83.31000  ? 223 ILE A HG21 1 
ATOM   3470 H  HG22 . ILE A 1 223 ? 3.82700   -28.21300 24.82800 1.000 83.31000  ? 223 ILE A HG22 1 
ATOM   3471 H  HG23 . ILE A 1 223 ? 2.85800   -26.99600 24.50800 1.000 83.31000  ? 223 ILE A HG23 1 
ATOM   3472 H  HD11 . ILE A 1 223 ? 0.08500   -26.79400 27.54100 1.000 84.75000  ? 223 ILE A HD11 1 
ATOM   3473 H  HD12 . ILE A 1 223 ? 1.10500   -27.96600 27.87200 1.000 84.75000  ? 223 ILE A HD12 1 
ATOM   3474 H  HD13 . ILE A 1 223 ? 1.62900   -26.62100 27.21100 1.000 84.75000  ? 223 ILE A HD13 1 
ATOM   3475 N  N    . PRO A 1 224 ? 0.19900   -31.22200 24.58000 1.000 76.81974  ? 224 PRO A N    1 
ATOM   3476 C  CA   . PRO A 1 224 ? -1.06300  -31.95900 24.71700 1.000 80.68599  ? 224 PRO A CA   1 
ATOM   3477 C  C    . PRO A 1 224 ? -1.93800  -31.37100 25.81300 1.000 79.16212  ? 224 PRO A C    1 
ATOM   3478 O  O    . PRO A 1 224 ? -1.44900  -30.92300 26.85300 1.000 78.86209  ? 224 PRO A O    1 
ATOM   3479 C  CB   . PRO A 1 224 ? -0.61700  -33.38600 25.06700 1.000 82.55990  ? 224 PRO A CB   1 
ATOM   3480 C  CG   . PRO A 1 224 ? 0.86400   -33.42500 24.83900 1.000 79.24634  ? 224 PRO A CG   1 
ATOM   3481 C  CD   . PRO A 1 224 ? 1.34900   -32.02700 25.02600 1.000 77.91987  ? 224 PRO A CD   1 
ATOM   3482 H  HA   . PRO A 1 224 ? -1.54700  -31.96200 23.87700 1.000 96.94000  ? 224 PRO A HA   1 
ATOM   3483 H  HB2  . PRO A 1 224 ? -0.82600  -33.57500 25.99500 1.000 99.18000  ? 224 PRO A HB2  1 
ATOM   3484 H  HB3  . PRO A 1 224 ? -1.07000  -34.02000 24.48900 1.000 99.18000  ? 224 PRO A HB3  1 
ATOM   3485 H  HG2  . PRO A 1 224 ? 1.27700   -34.02000 25.48300 1.000 95.21000  ? 224 PRO A HG2  1 
ATOM   3486 H  HG3  . PRO A 1 224 ? 1.04600   -33.73300 23.93700 1.000 95.21000  ? 224 PRO A HG3  1 
ATOM   3487 H  HD2  . PRO A 1 224 ? 1.55500   -31.85300 25.95800 1.000 93.62000  ? 224 PRO A HD2  1 
ATOM   3488 H  HD3  . PRO A 1 224 ? 2.12900   -31.85400 24.47600 1.000 93.62000  ? 224 PRO A HD3  1 
ATOM   3489 N  N    . CYS A 1 225 ? -3.24400  -31.37700 25.56700 1.000 79.87010  ? 225 CYS A N    1 
ATOM   3490 C  CA   . CYS A 1 225 ? -4.23800  -30.99100 26.55500 1.000 78.24096  ? 225 CYS A CA   1 
ATOM   3491 C  C    . CYS A 1 225 ? -5.01400  -32.22500 26.99800 1.000 83.87848  ? 225 CYS A C    1 
ATOM   3492 O  O    . CYS A 1 225 ? -5.12800  -33.20600 26.25700 1.000 80.12276  ? 225 CYS A O    1 
ATOM   3493 C  CB   . CYS A 1 225 ? -5.20000  -29.93900 25.99600 1.000 76.12492  ? 225 CYS A CB   1 
ATOM   3494 S  SG   . CYS A 1 225 ? -6.51200  -29.46100 27.14500 1.000 84.14430  ? 225 CYS A SG   1 
ATOM   3495 H  H    . CYS A 1 225 ? -3.58500  -31.60800 24.81200 1.000 95.96000  ? 225 CYS A H    1 
ATOM   3496 H  HA   . CYS A 1 225 ? -3.79900  -30.60500 27.32900 1.000 94.00000  ? 225 CYS A HA   1 
ATOM   3497 H  HB2  . CYS A 1 225 ? -4.69400  -29.14100 25.77600 1.000 91.46000  ? 225 CYS A HB2  1 
ATOM   3498 H  HB3  . CYS A 1 225 ? -5.62100  -30.29600 25.19900 1.000 91.46000  ? 225 CYS A HB3  1 
ATOM   3499 N  N    . THR A 1 226 ? -5.54600  -32.16800 28.22100 1.000 88.19742  ? 226 THR A N    1 
ATOM   3500 C  CA   . THR A 1 226 ? -6.24800  -33.32500 28.76800 1.000 90.93985  ? 226 THR A CA   1 
ATOM   3501 C  C    . THR A 1 226 ? -7.40800  -33.75600 27.87700 1.000 87.92107  ? 226 THR A C    1 
ATOM   3502 O  O    . THR A 1 226 ? -7.72400  -34.95000 27.80900 1.000 83.58634  ? 226 THR A O    1 
ATOM   3503 C  CB   . THR A 1 226 ? -6.75200  -33.02300 30.18400 1.000 92.05051  ? 226 THR A CB   1 
ATOM   3504 O  OG1  . THR A 1 226 ? -7.67800  -34.03900 30.59200 1.000 90.03185  ? 226 THR A OG1  1 
ATOM   3505 C  CG2  . THR A 1 226 ? -7.43700  -31.66100 30.25100 1.000 90.44242  ? 226 THR A CG2  1 
ATOM   3506 H  H    . THR A 1 226 ? -5.51500  -31.48500 28.74300 1.000 105.95000 ? 226 THR A H    1 
ATOM   3507 H  HA   . THR A 1 226 ? -5.62200  -34.06300 28.82500 1.000 109.24000 ? 226 THR A HA   1 
ATOM   3508 H  HB   . THR A 1 226 ? -5.99600  -33.00600 30.79000 1.000 110.58000 ? 226 THR A HB   1 
ATOM   3509 H  HG1  . THR A 1 226 ? -7.93500  -33.89500 31.37900 1.000 108.15000 ? 226 THR A HG1  1 
ATOM   3510 H  HG21 . THR A 1 226 ? -7.97700  -31.60000 31.05400 1.000 108.65000 ? 226 THR A HG21 1 
ATOM   3511 H  HG22 . THR A 1 226 ? -6.77200  -30.95500 30.26500 1.000 108.65000 ? 226 THR A HG22 1 
ATOM   3512 H  HG23 . THR A 1 226 ? -8.00900  -31.53900 29.47700 1.000 108.65000 ? 226 THR A HG23 1 
ATOM   3513 N  N    . CYS A 1 227 ? -8.04700  -32.81100 27.18200 1.000 88.32375  ? 227 CYS A N    1 
ATOM   3514 C  CA   . CYS A 1 227 ? -9.18100  -33.15700 26.33200 1.000 86.85778  ? 227 CYS A CA   1 
ATOM   3515 C  C    . CYS A 1 227 ? -8.76900  -33.96600 25.11000 1.000 80.07539  ? 227 CYS A C    1 
ATOM   3516 O  O    . CYS A 1 227 ? -9.63200  -34.56900 24.46300 1.000 77.20663  ? 227 CYS A O    1 
ATOM   3517 C  CB   . CYS A 1 227 ? -9.91100  -31.88900 25.88200 1.000 90.04501  ? 227 CYS A CB   1 
ATOM   3518 S  SG   . CYS A 1 227 ? -8.99600  -30.87700 24.69600 1.000 82.96521  ? 227 CYS A SG   1 
ATOM   3519 H  H    . CYS A 1 227 ? -7.84500  -31.97500 27.18700 1.000 106.10000 ? 227 CYS A H    1 
ATOM   3520 H  HA   . CYS A 1 227 ? -9.79900  -33.69300 26.85300 1.000 104.34000 ? 227 CYS A HA   1 
ATOM   3521 H  HB2  . CYS A 1 227 ? -10.74700 -32.14600 25.46300 1.000 108.17000 ? 227 CYS A HB2  1 
ATOM   3522 H  HB3  . CYS A 1 227 ? -10.08500 -31.33900 26.66200 1.000 108.17000 ? 227 CYS A HB3  1 
ATOM   3523 N  N    . GLY A 1 228 ? -7.47800  -33.99500 24.78100 1.000 81.61242  ? 228 GLY A N    1 
ATOM   3524 C  CA   . GLY A 1 228 ? -6.97300  -34.68900 23.61700 1.000 75.21428  ? 228 GLY A CA   1 
ATOM   3525 C  C    . GLY A 1 228 ? -6.47200  -33.77300 22.52100 1.000 75.66434  ? 228 GLY A C    1 
ATOM   3526 O  O    . GLY A 1 228 ? -5.67800  -34.21200 21.67800 1.000 68.10817  ? 228 GLY A O    1 
ATOM   3527 H  H    . GLY A 1 228 ? -6.86200  -33.60300 25.23600 1.000 98.05000  ? 228 GLY A H    1 
ATOM   3528 H  HA2  . GLY A 1 228 ? -6.23800  -35.26200 23.88700 1.000 90.37000  ? 228 GLY A HA2  1 
ATOM   3529 H  HA3  . GLY A 1 228 ? -7.68200  -35.23800 23.24600 1.000 90.37000  ? 228 GLY A HA3  1 
ATOM   3530 N  N    . LYS A 1 229 ? -6.91200  -32.51700 22.50800 1.000 80.58598  ? 229 LYS A N    1 
ATOM   3531 C  CA   . LYS A 1 229 ? -6.44000  -31.55900 21.52200 1.000 75.84594  ? 229 LYS A CA   1 
ATOM   3532 C  C    . LYS A 1 229 ? -4.98000  -31.20200 21.79100 1.000 78.94368  ? 229 LYS A C    1 
ATOM   3533 O  O    . LYS A 1 229 ? -4.36000  -31.65900 22.75600 1.000 78.91209  ? 229 LYS A O    1 
ATOM   3534 C  CB   . LYS A 1 229 ? -7.30200  -30.29800 21.54800 1.000 80.73600  ? 229 LYS A CB   1 
ATOM   3535 C  CG   . LYS A 1 229 ? -8.67400  -30.46100 20.92500 1.000 78.07515  ? 229 LYS A CG   1 
ATOM   3536 C  CD   . LYS A 1 229 ? -9.07800  -29.23200 20.12000 1.000 82.56253  ? 229 LYS A CD   1 
ATOM   3537 C  CE   . LYS A 1 229 ? -9.93200  -29.62000 18.93000 1.000 72.90085  ? 229 LYS A CE   1 
ATOM   3538 N  NZ   . LYS A 1 229 ? -9.11000  -29.83100 17.70800 1.000 79.88326  ? 229 LYS A NZ   1 
ATOM   3539 H  H    . LYS A 1 229 ? -7.48600  -32.19600 23.06200 1.000 96.82000  ? 229 LYS A H    1 
ATOM   3540 H  HA   . LYS A 1 229 ? -6.50900  -31.96500 20.64400 1.000 91.13000  ? 229 LYS A HA   1 
ATOM   3541 H  HB2  . LYS A 1 229 ? -7.42900  -30.03000 22.47100 1.000 97.00000  ? 229 LYS A HB2  1 
ATOM   3542 H  HB3  . LYS A 1 229 ? -6.84000  -29.59800 21.06000 1.000 97.00000  ? 229 LYS A HB3  1 
ATOM   3543 H  HG2  . LYS A 1 229 ? -8.66700  -31.22600 20.32800 1.000 93.80000  ? 229 LYS A HG2  1 
ATOM   3544 H  HG3  . LYS A 1 229 ? -9.33100  -30.59400 21.62600 1.000 93.80000  ? 229 LYS A HG3  1 
ATOM   3545 H  HD2  . LYS A 1 229 ? -9.59100  -28.63200 20.68300 1.000 99.19000  ? 229 LYS A HD2  1 
ATOM   3546 H  HD3  . LYS A 1 229 ? -8.28300  -28.78300 19.79400 1.000 99.19000  ? 229 LYS A HD3  1 
ATOM   3547 H  HE2  . LYS A 1 229 ? -10.40000 -30.44600 19.12800 1.000 87.59000  ? 229 LYS A HE2  1 
ATOM   3548 H  HE3  . LYS A 1 229 ? -10.56900 -28.91200 18.74900 1.000 87.59000  ? 229 LYS A HE3  1 
ATOM   3549 H  HZ1  . LYS A 1 229 ? -9.63200  -30.06200 17.02600 1.000 95.97000  ? 229 LYS A HZ1  1 
ATOM   3550 H  HZ2  . LYS A 1 229 ? -8.67600  -29.08200 17.50000 1.000 95.97000  ? 229 LYS A HZ2  1 
ATOM   3551 H  HZ3  . LYS A 1 229 ? -8.51600  -30.47900 17.84900 1.000 95.97000  ? 229 LYS A HZ3  1 
ATOM   3552 N  N    . GLN A 1 230 ? -4.43100  -30.36300 20.91900 1.000 77.10661  ? 230 GLN A N    1 
ATOM   3553 C  CA   . GLN A 1 230 ? -3.09500  -29.80100 21.08300 1.000 80.78863  ? 230 GLN A CA   1 
ATOM   3554 C  C    . GLN A 1 230 ? -3.24000  -28.33700 21.47500 1.000 78.70681  ? 230 GLN A C    1 
ATOM   3555 O  O    . GLN A 1 230 ? -3.73500  -27.52500 20.68700 1.000 77.74616  ? 230 GLN A O    1 
ATOM   3556 C  CB   . GLN A 1 230 ? -2.28000  -29.93800 19.80100 1.000 80.12276  ? 230 GLN A CB   1 
ATOM   3557 C  CG   . GLN A 1 230 ? -1.69300  -31.31900 19.59200 1.000 83.31788  ? 230 GLN A CG   1 
ATOM   3558 C  CD   . GLN A 1 230 ? -0.18400  -31.33500 19.71500 1.000 87.57629  ? 230 GLN A CD   1 
ATOM   3559 O  OE1  . GLN A 1 230 ? 0.53200   -31.00900 18.76700 1.000 87.30520  ? 230 GLN A OE1  1 
ATOM   3560 N  NE2  . GLN A 1 230 ? 0.31000   -31.71400 20.88800 1.000 87.07886  ? 230 GLN A NE2  1 
ATOM   3561 H  H    . GLN A 1 230 ? -4.82500  -30.09600 20.20300 1.000 92.64000  ? 230 GLN A H    1 
ATOM   3562 H  HA   . GLN A 1 230 ? -2.63500  -30.27400 21.79400 1.000 97.06000  ? 230 GLN A HA   1 
ATOM   3563 H  HB2  . GLN A 1 230 ? -2.85500  -29.74400 19.04500 1.000 96.26000  ? 230 GLN A HB2  1 
ATOM   3564 H  HB3  . GLN A 1 230 ? -1.54500  -29.30600 19.83100 1.000 96.26000  ? 230 GLN A HB3  1 
ATOM   3565 H  HG2  . GLN A 1 230 ? -2.05500  -31.92200 20.26000 1.000 100.09000 ? 230 GLN A HG2  1 
ATOM   3566 H  HG3  . GLN A 1 230 ? -1.92500  -31.63000 18.70300 1.000 100.09000 ? 230 GLN A HG3  1 
ATOM   3567 H  HE21 . GLN A 1 230 ? -0.22200  -31.93400 21.52800 1.000 104.61000 ? 230 GLN A HE21 1 
ATOM   3568 H  HE22 . GLN A 1 230 ? 1.16100   -31.73900 21.00900 1.000 104.61000 ? 230 GLN A HE22 1 
ATOM   3569 N  N    . ALA A 1 231 ? -2.80900  -28.00400 22.68600 1.000 80.36227  ? 231 ALA A N    1 
ATOM   3570 C  CA   . ALA A 1 231 ? -2.85500  -26.63400 23.16600 1.000 79.63060  ? 231 ALA A CA   1 
ATOM   3571 C  C    . ALA A 1 231 ? -1.59000  -25.88600 22.75800 1.000 79.58059  ? 231 ALA A C    1 
ATOM   3572 O  O    . ALA A 1 231 ? -0.57800  -26.48200 22.38300 1.000 77.99619  ? 231 ALA A O    1 
ATOM   3573 C  CB   . ALA A 1 231 ? -3.02000  -26.60000 24.68600 1.000 77.75932  ? 231 ALA A CB   1 
ATOM   3574 H  H    . ALA A 1 231 ? -2.48200  -28.56200 23.25300 1.000 96.55000  ? 231 ALA A H    1 
ATOM   3575 H  HA   . ALA A 1 231 ? -3.61800  -26.18000 22.77300 1.000 95.67000  ? 231 ALA A HA   1 
ATOM   3576 H  HB1  . ALA A 1 231 ? -3.04800  -25.67600 24.98000 1.000 93.42000  ? 231 ALA A HB1  1 
ATOM   3577 H  HB2  . ALA A 1 231 ? -3.84600  -27.04900 24.92400 1.000 93.42000  ? 231 ALA A HB2  1 
ATOM   3578 H  HB3  . ALA A 1 231 ? -2.26700  -27.05500 25.09500 1.000 93.42000  ? 231 ALA A HB3  1 
ATOM   3579 N  N    . THR A 1 232 ? -1.66300  -24.55900 22.83700 1.000 76.06702  ? 232 THR A N    1 
ATOM   3580 C  CA   . THR A 1 232 ? -0.54900  -23.68000 22.50000 1.000 77.57772  ? 232 THR A CA   1 
ATOM   3581 C  C    . THR A 1 232 ? -0.11400  -22.94700 23.76100 1.000 74.58526  ? 232 THR A C    1 
ATOM   3582 O  O    . THR A 1 232 ? -0.91100  -22.22300 24.36700 1.000 72.16392  ? 232 THR A O    1 
ATOM   3583 C  CB   . THR A 1 232 ? -0.94300  -22.68900 21.40000 1.000 76.74078  ? 232 THR A CB   1 
ATOM   3584 O  OG1  . THR A 1 232 ? -0.84200  -23.33200 20.12200 1.000 82.02299  ? 232 THR A OG1  1 
ATOM   3585 C  CG2  . THR A 1 232 ? -0.04100  -21.45100 21.41000 1.000 78.00409  ? 232 THR A CG2  1 
ATOM   3586 H  H    . THR A 1 232 ? -2.36700  -24.13500 23.09000 1.000 91.40000  ? 232 THR A H    1 
ATOM   3587 H  HA   . THR A 1 232 ? 0.19900   -24.20700 22.17800 1.000 93.21000  ? 232 THR A HA   1 
ATOM   3588 H  HB   . THR A 1 232 ? -1.85500  -22.39500 21.55500 1.000 92.20000  ? 232 THR A HB   1 
ATOM   3589 H  HG1  . THR A 1 232 ? -1.04500  -22.79100 19.51200 1.000 98.54000  ? 232 THR A HG1  1 
ATOM   3590 H  HG21 . THR A 1 232 ? -0.28900  -20.85500 20.68600 1.000 93.72000  ? 232 THR A HG21 1 
ATOM   3591 H  HG22 . THR A 1 232 ? -0.13500  -20.98000 22.25200 1.000 93.72000  ? 232 THR A HG22 1 
ATOM   3592 H  HG23 . THR A 1 232 ? 0.88500   -21.71500 21.29800 1.000 93.72000  ? 232 THR A HG23 1 
ATOM   3593 N  N    . LYS A 1 233 ? 1.14300   -23.13500 24.14800 1.000 73.98519  ? 233 LYS A N    1 
ATOM   3594 C  CA   . LYS A 1 233 ? 1.74200   -22.44900 25.28500 1.000 75.35114  ? 233 LYS A CA   1 
ATOM   3595 C  C    . LYS A 1 233 ? 2.73900   -21.42300 24.76400 1.000 74.06941  ? 233 LYS A C    1 
ATOM   3596 O  O    . LYS A 1 233 ? 3.59600   -21.75300 23.93700 1.000 74.11941  ? 233 LYS A O    1 
ATOM   3597 C  CB   . LYS A 1 233 ? 2.42800   -23.44900 26.22100 1.000 69.04249  ? 233 LYS A CB   1 
ATOM   3598 C  CG   . LYS A 1 233 ? 3.49700   -22.85600 27.13500 1.000 74.68001  ? 233 LYS A CG   1 
ATOM   3599 C  CD   . LYS A 1 233 ? 4.17300   -23.93200 27.98300 1.000 69.02933  ? 233 LYS A CD   1 
ATOM   3600 C  CE   . LYS A 1 233 ? 3.24600   -24.47800 29.06000 1.000 69.30568  ? 233 LYS A CE   1 
ATOM   3601 N  NZ   . LYS A 1 233 ? 3.83100   -25.66200 29.75100 1.000 68.01868  ? 233 LYS A NZ   1 
ATOM   3602 H  H    . LYS A 1 233 ? 1.68600   -23.67300 23.75400 1.000 88.89000  ? 233 LYS A H    1 
ATOM   3603 H  HA   . LYS A 1 233 ? 1.06200   -21.98200 25.79600 1.000 90.53000  ? 233 LYS A HA   1 
ATOM   3604 H  HB2  . LYS A 1 233 ? 1.75200   -23.85100 26.78900 1.000 82.96000  ? 233 LYS A HB2  1 
ATOM   3605 H  HB3  . LYS A 1 233 ? 2.85500   -24.13200 25.68000 1.000 82.96000  ? 233 LYS A HB3  1 
ATOM   3606 H  HG2  . LYS A 1 233 ? 4.17600   -22.42300 26.59500 1.000 89.73000  ? 233 LYS A HG2  1 
ATOM   3607 H  HG3  . LYS A 1 233 ? 3.08700   -22.21100 27.73200 1.000 89.73000  ? 233 LYS A HG3  1 
ATOM   3608 H  HD2  . LYS A 1 233 ? 4.43900   -24.66900 27.41100 1.000 82.95000  ? 233 LYS A HD2  1 
ATOM   3609 H  HD3  . LYS A 1 233 ? 4.95200   -23.55200 28.41800 1.000 82.95000  ? 233 LYS A HD3  1 
ATOM   3610 H  HE2  . LYS A 1 233 ? 3.08600   -23.78800 29.72400 1.000 83.28000  ? 233 LYS A HE2  1 
ATOM   3611 H  HE3  . LYS A 1 233 ? 2.40800   -24.74800 28.65400 1.000 83.28000  ? 233 LYS A HE3  1 
ATOM   3612 H  HZ1  . LYS A 1 233 ? 3.26600   -25.96400 30.36900 1.000 81.74000  ? 233 LYS A HZ1  1 
ATOM   3613 H  HZ2  . LYS A 1 233 ? 3.99000   -26.31000 29.16200 1.000 81.74000  ? 233 LYS A HZ2  1 
ATOM   3614 H  HZ3  . LYS A 1 233 ? 4.59700   -25.43600 30.14500 1.000 81.74000  ? 233 LYS A HZ3  1 
ATOM   3615 N  N    . TYR A 1 234 ? 2.62200   -20.18400 25.23800 1.000 70.87692  ? 234 TYR A N    1 
ATOM   3616 C  CA   . TYR A 1 234 ? 3.52800   -19.12100 24.82700 1.000 70.37686  ? 234 TYR A CA   1 
ATOM   3617 C  C    . TYR A 1 234 ? 3.89800   -18.27000 26.03300 1.000 66.58956  ? 234 TYR A C    1 
ATOM   3618 O  O    . TYR A 1 234 ? 3.22900   -18.29200 27.06900 1.000 69.31094  ? 234 TYR A O    1 
ATOM   3619 C  CB   . TYR A 1 234 ? 2.91600   -18.24200 23.72600 1.000 69.21356  ? 234 TYR A CB   1 
ATOM   3620 C  CG   . TYR A 1 234 ? 1.69700   -17.46000 24.15600 1.000 73.71937  ? 234 TYR A CG   1 
ATOM   3621 C  CD1  . TYR A 1 234 ? 0.44400   -18.05600 24.19600 1.000 73.92202  ? 234 TYR A CD1  1 
ATOM   3622 C  CD2  . TYR A 1 234 ? 1.79600   -16.12100 24.50800 1.000 77.06713  ? 234 TYR A CD2  1 
ATOM   3623 C  CE1  . TYR A 1 234 ? -0.67500  -17.34300 24.58300 1.000 78.75681  ? 234 TYR A CE1  1 
ATOM   3624 C  CE2  . TYR A 1 234 ? 0.68400   -15.40000 24.89700 1.000 78.66733  ? 234 TYR A CE2  1 
ATOM   3625 C  CZ   . TYR A 1 234 ? -0.55000  -16.01600 24.93300 1.000 78.87261  ? 234 TYR A CZ   1 
ATOM   3626 O  OH   . TYR A 1 234 ? -1.66200  -15.30200 25.31900 1.000 78.11989  ? 234 TYR A OH   1 
ATOM   3627 H  H    . TYR A 1 234 ? 2.02200   -19.93500 25.80200 1.000 85.17000  ? 234 TYR A H    1 
ATOM   3628 H  HA   . TYR A 1 234 ? 4.34100   -19.51800 24.47900 1.000 84.56000  ? 234 TYR A HA   1 
ATOM   3629 H  HB2  . TYR A 1 234 ? 3.58500   -17.60400 23.43300 1.000 83.17000  ? 234 TYR A HB2  1 
ATOM   3630 H  HB3  . TYR A 1 234 ? 2.65300   -18.81200 22.98700 1.000 83.17000  ? 234 TYR A HB3  1 
ATOM   3631 H  HD1  . TYR A 1 234 ? 0.35600   -18.95100 23.95800 1.000 92.59000  ? 234 TYR A HD1  1 
ATOM   3632 H  HD2  . TYR A 1 234 ? 2.62600   -15.70200 24.48300 1.000 88.82000  ? 234 TYR A HD2  1 
ATOM   3633 H  HE1  . TYR A 1 234 ? -1.50800  -17.75700 24.60700 1.000 94.51000  ? 234 TYR A HE1  1 
ATOM   3634 H  HE2  . TYR A 1 234 ? 0.76600   -14.50400 25.13400 1.000 94.62000  ? 234 TYR A HE2  1 
ATOM   3635 H  HH   . TYR A 1 234 ? -2.33600  -15.80400 25.32900 1.000 93.86000  ? 234 TYR A HH   1 
ATOM   3636 N  N    . LEU A 1 235 ? 4.98100   -17.51200 25.87700 1.000 64.23402  ? 235 LEU A N    1 
ATOM   3637 C  CA   . LEU A 1 235 ? 5.55700   -16.72900 26.96300 1.000 65.99475  ? 235 LEU A CA   1 
ATOM   3638 C  C    . LEU A 1 235 ? 4.84700   -15.38400 27.06100 1.000 65.67630  ? 235 LEU A C    1 
ATOM   3639 O  O    . LEU A 1 235 ? 4.81800   -14.61800 26.09100 1.000 67.85550  ? 235 LEU A O    1 
ATOM   3640 C  CB   . LEU A 1 235 ? 7.05500   -16.53200 26.73400 1.000 63.49445  ? 235 LEU A CB   1 
ATOM   3641 C  CG   . LEU A 1 235 ? 7.80900   -15.68000 27.75400 1.000 62.94965  ? 235 LEU A CG   1 
ATOM   3642 C  CD1  . LEU A 1 235 ? 7.70700   -16.28000 29.14700 1.000 59.60715  ? 235 LEU A CD1  1 
ATOM   3643 C  CD2  . LEU A 1 235 ? 9.26300   -15.53800 27.33400 1.000 60.32302  ? 235 LEU A CD2  1 
ATOM   3644 H  H    . LEU A 1 235 ? 5.40800   -17.43400 25.13500 1.000 77.19000  ? 235 LEU A H    1 
ATOM   3645 H  HA   . LEU A 1 235 ? 5.42800   -17.19700 27.80300 1.000 79.31000  ? 235 LEU A HA   1 
ATOM   3646 H  HB2  . LEU A 1 235 ? 7.47300   -17.40700 26.73200 1.000 76.31000  ? 235 LEU A HB2  1 
ATOM   3647 H  HB3  . LEU A 1 235 ? 7.17100   -16.10700 25.87000 1.000 76.31000  ? 235 LEU A HB3  1 
ATOM   3648 H  HG   . LEU A 1 235 ? 7.41000   -14.79700 27.78900 1.000 75.66000  ? 235 LEU A HG   1 
ATOM   3649 H  HD11 . LEU A 1 235 ? 8.25800   -15.76300 29.75500 1.000 71.64000  ? 235 LEU A HD11 1 
ATOM   3650 H  HD12 . LEU A 1 235 ? 6.78100   -16.25100 29.43500 1.000 71.64000  ? 235 LEU A HD12 1 
ATOM   3651 H  HD13 . LEU A 1 235 ? 8.01700   -17.19800 29.11900 1.000 71.64000  ? 235 LEU A HD13 1 
ATOM   3652 H  HD21 . LEU A 1 235 ? 9.69400   -14.88300 27.90600 1.000 72.50000  ? 235 LEU A HD21 1 
ATOM   3653 H  HD22 . LEU A 1 235 ? 9.70400   -16.39700 27.42400 1.000 72.50000  ? 235 LEU A HD22 1 
ATOM   3654 H  HD23 . LEU A 1 235 ? 9.29700   -15.24400 26.41000 1.000 72.50000  ? 235 LEU A HD23 1 
ATOM   3655 N  N    . VAL A 1 236 ? 4.28100   -15.10000 28.23000 1.000 66.54219  ? 236 VAL A N    1 
ATOM   3656 C  CA   . VAL A 1 236 ? 3.59600   -13.83100 28.46100 1.000 67.67654  ? 236 VAL A CA   1 
ATOM   3657 C  C    . VAL A 1 236 ? 4.55400   -12.77500 28.99500 1.000 66.17899  ? 236 VAL A C    1 
ATOM   3658 O  O    . VAL A 1 236 ? 4.59600   -11.64900 28.49400 1.000 66.21320  ? 236 VAL A O    1 
ATOM   3659 C  CB   . VAL A 1 236 ? 2.40700   -14.04200 29.42400 1.000 69.13197  ? 236 VAL A CB   1 
ATOM   3660 C  CG1  . VAL A 1 236 ? 1.64100   -12.74100 29.61500 1.000 66.83696  ? 236 VAL A CG1  1 
ATOM   3661 C  CG2  . VAL A 1 236 ? 1.48800   -15.13900 28.90800 1.000 70.89271  ? 236 VAL A CG2  1 
ATOM   3662 H  H    . VAL A 1 236 ? 4.28100   -15.62700 28.90900 1.000 79.96000  ? 236 VAL A H    1 
ATOM   3663 H  HA   . VAL A 1 236 ? 3.24500   -13.51500 27.61400 1.000 81.33000  ? 236 VAL A HA   1 
ATOM   3664 H  HB   . VAL A 1 236 ? 2.74900   -14.32000 30.28800 1.000 83.07000  ? 236 VAL A HB   1 
ATOM   3665 H  HG11 . VAL A 1 236 ? 0.81700   -12.92700 30.09100 1.000 80.32000  ? 236 VAL A HG11 1 
ATOM   3666 H  HG12 . VAL A 1 236 ? 2.18700   -12.12500 30.12700 1.000 80.32000  ? 236 VAL A HG12 1 
ATOM   3667 H  HG13 . VAL A 1 236 ? 1.44200   -12.36100 28.74500 1.000 80.32000  ? 236 VAL A HG13 1 
ATOM   3668 H  HG21 . VAL A 1 236 ? 0.69600   -15.17600 29.46700 1.000 85.18000  ? 236 VAL A HG21 1 
ATOM   3669 H  HG22 . VAL A 1 236 ? 1.23900   -14.93800 27.99300 1.000 85.18000  ? 236 VAL A HG22 1 
ATOM   3670 H  HG23 . VAL A 1 236 ? 1.95800   -15.98700 28.94400 1.000 85.18000  ? 236 VAL A HG23 1 
ATOM   3671 N  N    . GLN A 1 237 ? 5.33400   -13.11900 30.01600 1.000 63.37076  ? 237 GLN A N    1 
ATOM   3672 C  CA   . GLN A 1 237 ? 6.24300   -12.16900 30.64000 1.000 68.17923  ? 237 GLN A CA   1 
ATOM   3673 C  C    . GLN A 1 237 ? 7.45000   -12.91900 31.18100 1.000 62.52855  ? 237 GLN A C    1 
ATOM   3674 O  O    . GLN A 1 237 ? 7.31900   -14.02600 31.71000 1.000 61.24419  ? 237 GLN A O    1 
ATOM   3675 C  CB   . GLN A 1 237 ? 5.55400   -11.39300 31.76900 1.000 65.97896  ? 237 GLN A CB   1 
ATOM   3676 C  CG   . GLN A 1 237 ? 6.34700   -10.19300 32.27000 1.000 71.38487  ? 237 GLN A CG   1 
ATOM   3677 C  CD   . GLN A 1 237 ? 5.98200   -9.79800  33.69000 1.000 86.77883  ? 237 GLN A CD   1 
ATOM   3678 O  OE1  . GLN A 1 237 ? 5.08500   -10.38400 34.29900 1.000 88.37375  ? 237 GLN A OE1  1 
ATOM   3679 N  NE2  . GLN A 1 237 ? 6.67800   -8.80200  34.22500 1.000 91.71100  ? 237 GLN A NE2  1 
ATOM   3680 H  H    . GLN A 1 237 ? 5.35400   -13.90400 30.36800 1.000 76.16000  ? 237 GLN A H    1 
ATOM   3681 H  HA   . GLN A 1 237 ? 6.55200   -11.53300 29.97600 1.000 81.93000  ? 237 GLN A HA   1 
ATOM   3682 H  HB2  . GLN A 1 237 ? 4.70000   -11.06700 31.44600 1.000 79.29000  ? 237 GLN A HB2  1 
ATOM   3683 H  HB3  . GLN A 1 237 ? 5.41900   -11.99100 32.52100 1.000 79.29000  ? 237 GLN A HB3  1 
ATOM   3684 H  HG2  . GLN A 1 237 ? 7.29300   -10.40900 32.25300 1.000 85.77000  ? 237 GLN A HG2  1 
ATOM   3685 H  HG3  . GLN A 1 237 ? 6.17000   -9.43300  31.69300 1.000 85.77000  ? 237 GLN A HG3  1 
ATOM   3686 H  HE21 . GLN A 1 237 ? 7.29800   -8.41700  33.77000 1.000 110.17000 ? 237 GLN A HE21 1 
ATOM   3687 H  HE22 . GLN A 1 237 ? 6.50900   -8.54100  35.02700 1.000 110.17000 ? 237 GLN A HE22 1 
ATOM   3688 N  N    . GLN A 1 238 ? 8.62200   -12.30400 31.04500 1.000 58.38068  ? 238 GLN A N    1 
ATOM   3689 C  CA   . GLN A 1 238 ? 9.86900   -12.87200 31.53500 1.000 61.09417  ? 238 GLN A CA   1 
ATOM   3690 C  C    . GLN A 1 238 ? 10.66300  -11.79000 32.24600 1.000 63.45234  ? 238 GLN A C    1 
ATOM   3691 O  O    . GLN A 1 238 ? 10.77700  -10.66400 31.75200 1.000 64.84725  ? 238 GLN A O    1 
ATOM   3692 C  CB   . GLN A 1 238 ? 10.70300  -13.46600 30.39300 1.000 60.18353  ? 238 GLN A CB   1 
ATOM   3693 C  CG   . GLN A 1 238 ? 11.98800  -14.15100 30.84200 1.000 60.10984  ? 238 GLN A CG   1 
ATOM   3694 C  CD   . GLN A 1 238 ? 11.73200  -15.42100 31.63100 1.000 60.47041  ? 238 GLN A CD   1 
ATOM   3695 O  OE1  . GLN A 1 238 ? 10.75600  -16.13100 31.38900 1.000 60.67833  ? 238 GLN A OE1  1 
ATOM   3696 N  NE2  . GLN A 1 238 ? 12.61600  -15.71800 32.57900 1.000 57.38320  ? 238 GLN A NE2  1 
ATOM   3697 H  H    . GLN A 1 238 ? 8.72100   -11.54000 30.66300 1.000 70.17000  ? 238 GLN A H    1 
ATOM   3698 H  HA   . GLN A 1 238 ? 9.67700   -13.58000 32.17000 1.000 73.43000  ? 238 GLN A HA   1 
ATOM   3699 H  HB2  . GLN A 1 238 ? 10.16500  -14.12600 29.92800 1.000 72.33000  ? 238 GLN A HB2  1 
ATOM   3700 H  HB3  . GLN A 1 238 ? 10.94800  -12.75100 29.78500 1.000 72.33000  ? 238 GLN A HB3  1 
ATOM   3701 H  HG2  . GLN A 1 238 ? 12.51100  -14.38500 30.05900 1.000 72.25000  ? 238 GLN A HG2  1 
ATOM   3702 H  HG3  . GLN A 1 238 ? 12.49000  -13.54300 31.40700 1.000 72.25000  ? 238 GLN A HG3  1 
ATOM   3703 H  HE21 . GLN A 1 238 ? 13.28800  -15.20000 32.71700 1.000 68.97000  ? 238 GLN A HE21 1 
ATOM   3704 H  HE22 . GLN A 1 238 ? 12.51500  -16.42700 33.05400 1.000 68.97000  ? 238 GLN A HE22 1 
ATOM   3705 N  N    . GLU A 1 239 ? 11.20800  -12.14000 33.40900 1.000 59.95719  ? 239 GLU A N    1 
ATOM   3706 C  CA   . GLU A 1 239 ? 12.06700  -11.24300 34.18100 1.000 61.10206  ? 239 GLU A CA   1 
ATOM   3707 C  C    . GLU A 1 239 ? 13.18700  -12.09800 34.76500 1.000 59.18868  ? 239 GLU A C    1 
ATOM   3708 O  O    . GLU A 1 239 ? 12.97800  -12.81400 35.74700 1.000 58.06749  ? 239 GLU A O    1 
ATOM   3709 C  CB   . GLU A 1 239 ? 11.28400  -10.52200 35.27200 1.000 64.87620  ? 239 GLU A CB   1 
ATOM   3710 C  CG   . GLU A 1 239 ? 11.55900  -9.02800  35.34200 1.000 76.16440  ? 239 GLU A CG   1 
ATOM   3711 C  CD   . GLU A 1 239 ? 11.10700  -8.41200  36.65200 1.000 94.49028  ? 239 GLU A CD   1 
ATOM   3712 O  OE1  . GLU A 1 239 ? 11.91100  -8.39100  37.60900 1.000 95.82728  ? 239 GLU A OE1  1 
ATOM   3713 O  OE2  . GLU A 1 239 ? 9.94900   -7.94800  36.72400 1.000 93.99285  ? 239 GLU A OE2  1 
ATOM   3714 H  H    . GLU A 1 239 ? 11.09300  -12.90700 33.78000 1.000 72.06000  ? 239 GLU A H    1 
ATOM   3715 H  HA   . GLU A 1 239 ? 12.45200  -10.57100 33.59700 1.000 73.44000  ? 239 GLU A HA   1 
ATOM   3716 H  HB2  . GLU A 1 239 ? 10.33600  -10.64100 35.10500 1.000 77.96000  ? 239 GLU A HB2  1 
ATOM   3717 H  HB3  . GLU A 1 239 ? 11.52000  -10.90700 36.13100 1.000 77.96000  ? 239 GLU A HB3  1 
ATOM   3718 H  HG2  . GLU A 1 239 ? 12.51300  -8.87800  35.25200 1.000 91.51000  ? 239 GLU A HG2  1 
ATOM   3719 H  HG3  . GLU A 1 239 ? 11.08400  -8.58500  34.62100 1.000 91.51000  ? 239 GLU A HG3  1 
ATOM   3720 N  N    . SER A 1 240 ? 14.36100  -12.03200 34.15200 1.000 53.28270  ? 240 SER A N    1 
ATOM   3721 C  CA   . SER A 1 240 ? 15.52100  -12.79600 34.59000 1.000 53.26165  ? 240 SER A CA   1 
ATOM   3722 C  C    . SER A 1 240 ? 16.73000  -12.32300 33.79100 1.000 56.11199  ? 240 SER A C    1 
ATOM   3723 O  O    . SER A 1 240 ? 16.57100  -11.73300 32.71900 1.000 53.79592  ? 240 SER A O    1 
ATOM   3724 C  CB   . SER A 1 240 ? 15.30500  -14.30600 34.39600 1.000 57.41741  ? 240 SER A CB   1 
ATOM   3725 O  OG   . SER A 1 240 ? 15.07300  -14.62500 33.03300 1.000 54.98554  ? 240 SER A OG   1 
ATOM   3726 H  H    . SER A 1 240 ? 14.51500  -11.54100 33.46300 1.000 64.05000  ? 240 SER A H    1 
ATOM   3727 H  HA   . SER A 1 240 ? 15.68800  -12.62900 35.53100 1.000 64.03000  ? 240 SER A HA   1 
ATOM   3728 H  HB2  . SER A 1 240 ? 16.09800  -14.77800 34.69700 1.000 69.02000  ? 240 SER A HB2  1 
ATOM   3729 H  HB3  . SER A 1 240 ? 14.53600  -14.58300 34.91800 1.000 69.02000  ? 240 SER A HB3  1 
ATOM   3730 H  HG   . SER A 1 240 ? 15.74300  -14.41800 32.57100 1.000 66.10000  ? 240 SER A HG   1 
ATOM   3731 N  N    . PRO A 1 241 ? 17.94400  -12.56700 34.29500 1.000 53.85383  ? 241 PRO A N    1 
ATOM   3732 C  CA   . PRO A 1 241 ? 19.14500  -12.17400 33.54300 1.000 54.84868  ? 241 PRO A CA   1 
ATOM   3733 C  C    . PRO A 1 241 ? 19.51300  -13.13700 32.43000 1.000 52.76422  ? 241 PRO A C    1 
ATOM   3734 O  O    . PRO A 1 241 ? 20.41900  -12.83000 31.64300 1.000 55.67246  ? 241 PRO A O    1 
ATOM   3735 C  CB   . PRO A 1 241 ? 20.24100  -12.13700 34.62000 1.000 58.32541  ? 241 PRO A CB   1 
ATOM   3736 C  CG   . PRO A 1 241 ? 19.72300  -12.95500 35.76900 1.000 55.05134  ? 241 PRO A CG   1 
ATOM   3737 C  CD   . PRO A 1 241 ? 18.27100  -13.27500 35.54500 1.000 52.51945  ? 241 PRO A CD   1 
ATOM   3738 H  HA   . PRO A 1 241 ? 19.03500  -11.28300 33.17700 1.000 65.93000  ? 241 PRO A HA   1 
ATOM   3739 H  HB2  . PRO A 1 241 ? 21.05800  -12.52100 34.26600 1.000 70.11000  ? 241 PRO A HB2  1 
ATOM   3740 H  HB3  . PRO A 1 241 ? 20.39700  -11.22000 34.89400 1.000 70.11000  ? 241 PRO A HB3  1 
ATOM   3741 H  HG2  . PRO A 1 241 ? 20.23700  -13.77600 35.82400 1.000 66.18000  ? 241 PRO A HG2  1 
ATOM   3742 H  HG3  . PRO A 1 241 ? 19.82600  -12.44400 36.58700 1.000 66.18000  ? 241 PRO A HG3  1 
ATOM   3743 H  HD2  . PRO A 1 241 ? 18.14200  -14.23100 35.44200 1.000 63.14000  ? 241 PRO A HD2  1 
ATOM   3744 H  HD3  . PRO A 1 241 ? 17.73000  -12.94400 36.27800 1.000 63.14000  ? 241 PRO A HD3  1 
ATOM   3745 N  N    . PHE A 1 242 ? 18.84600  -14.28200 32.34300 1.000 50.61396  ? 242 PHE A N    1 
ATOM   3746 C  CA   . PHE A 1 242 ? 19.11700  -15.27900 31.31700 1.000 49.08746  ? 242 PHE A CA   1 
ATOM   3747 C  C    . PHE A 1 242 ? 17.95400  -16.25800 31.31600 1.000 51.02980  ? 242 PHE A C    1 
ATOM   3748 O  O    . PHE A 1 242 ? 17.12800  -16.27100 32.23300 1.000 50.98243  ? 242 PHE A O    1 
ATOM   3749 C  CB   . PHE A 1 242 ? 20.44000  -16.00900 31.56500 1.000 52.39049  ? 242 PHE A CB   1 
ATOM   3750 C  CG   . PHE A 1 242 ? 20.41900  -16.90400 32.77500 1.000 53.03004  ? 242 PHE A CG   1 
ATOM   3751 C  CD1  . PHE A 1 242 ? 19.97500  -18.21400 32.68200 1.000 51.10086  ? 242 PHE A CD1  1 
ATOM   3752 C  CD2  . PHE A 1 242 ? 20.83900  -16.43000 34.00600 1.000 51.79042  ? 242 PHE A CD2  1 
ATOM   3753 C  CE1  . PHE A 1 242 ? 19.95200  -19.03300 33.79600 1.000 56.09094  ? 242 PHE A CE1  1 
ATOM   3754 C  CE2  . PHE A 1 242 ? 20.81800  -17.24500 35.12400 1.000 53.38008  ? 242 PHE A CE2  1 
ATOM   3755 C  CZ   . PHE A 1 242 ? 20.37400  -18.54700 35.01800 1.000 54.91711  ? 242 PHE A CZ   1 
ATOM   3756 H  H    . PHE A 1 242 ? 18.21500  -14.51100 32.88100 1.000 60.85000  ? 242 PHE A H    1 
ATOM   3757 H  HA   . PHE A 1 242 ? 19.17000  -14.84600 30.45000 1.000 59.02000  ? 242 PHE A HA   1 
ATOM   3758 H  HB2  . PHE A 1 242 ? 20.64200  -16.56000 30.79300 1.000 62.98000  ? 242 PHE A HB2  1 
ATOM   3759 H  HB3  . PHE A 1 242 ? 21.14000  -15.35100 31.69500 1.000 62.98000  ? 242 PHE A HB3  1 
ATOM   3760 H  HD1  . PHE A 1 242 ? 19.69000  -18.54600 31.86200 1.000 61.43000  ? 242 PHE A HD1  1 
ATOM   3761 H  HD2  . PHE A 1 242 ? 21.13800  -15.55300 34.08300 1.000 62.26000  ? 242 PHE A HD2  1 
ATOM   3762 H  HE1  . PHE A 1 242 ? 19.65300  -19.91000 33.72300 1.000 67.42000  ? 242 PHE A HE1  1 
ATOM   3763 H  HE2  . PHE A 1 242 ? 21.10200  -16.91500 35.94500 1.000 64.17000  ? 242 PHE A HE2  1 
ATOM   3764 H  HZ   . PHE A 1 242 ? 20.36000  -19.09600 35.76900 1.000 66.02000  ? 242 PHE A HZ   1 
ATOM   3765 N  N    . VAL A 1 243 ? 17.90300  -17.08400 30.27600 1.000 49.48751  ? 243 VAL A N    1 
ATOM   3766 C  CA   . VAL A 1 243 ? 16.95900  -18.19000 30.21000 1.000 47.87679  ? 243 VAL A CA   1 
ATOM   3767 C  C    . VAL A 1 243 ? 17.67300  -19.38500 29.60000 1.000 45.31596  ? 243 VAL A C    1 
ATOM   3768 O  O    . VAL A 1 243 ? 18.60600  -19.23900 28.80600 1.000 50.50869  ? 243 VAL A O    1 
ATOM   3769 C  CB   . VAL A 1 243 ? 15.69300  -17.84200 29.40000 1.000 50.99559  ? 243 VAL A CB   1 
ATOM   3770 C  CG1  . VAL A 1 243 ? 14.93900  -16.70300 30.07000 1.000 48.35580  ? 243 VAL A CG1  1 
ATOM   3771 C  CG2  . VAL A 1 243 ? 16.05000  -17.49500 27.96100 1.000 53.01951  ? 243 VAL A CG2  1 
ATOM   3772 H  H    . VAL A 1 243 ? 18.41200  -17.02100 29.58600 1.000 59.50000  ? 243 VAL A H    1 
ATOM   3773 H  HA   . VAL A 1 243 ? 16.67700  -18.41800 31.10900 1.000 57.57000  ? 243 VAL A HA   1 
ATOM   3774 H  HB   . VAL A 1 243 ? 15.10800  -18.61600 29.37600 1.000 61.31000  ? 243 VAL A HB   1 
ATOM   3775 H  HG11 . VAL A 1 243 ? 14.11200  -16.54500 29.58700 1.000 58.14000  ? 243 VAL A HG11 1 
ATOM   3776 H  HG12 . VAL A 1 243 ? 14.74400  -16.95000 30.98700 1.000 58.14000  ? 243 VAL A HG12 1 
ATOM   3777 H  HG13 . VAL A 1 243 ? 15.49100  -15.90500 30.05100 1.000 58.14000  ? 243 VAL A HG13 1 
ATOM   3778 H  HG21 . VAL A 1 243 ? 15.26000  -17.15700 27.51200 1.000 63.74000  ? 243 VAL A HG21 1 
ATOM   3779 H  HG22 . VAL A 1 243 ? 16.74500  -16.81800 27.96300 1.000 63.74000  ? 243 VAL A HG22 1 
ATOM   3780 H  HG23 . VAL A 1 243 ? 16.36900  -18.29500 27.51300 1.000 63.74000  ? 243 VAL A HG23 1 
ATOM   3781 N  N    . MET A 1 244 ? 17.22900  -20.57600 29.99000 1.000 46.46347  ? 244 MET A N    1 
ATOM   3782 C  CA   . MET A 1 244 ? 17.78500  -21.83100 29.50700 1.000 46.03973  ? 244 MET A CA   1 
ATOM   3783 C  C    . MET A 1 244 ? 16.68700  -22.58100 28.77200 1.000 45.13436  ? 244 MET A C    1 
ATOM   3784 O  O    . MET A 1 244 ? 15.66200  -22.92800 29.36800 1.000 51.88254  ? 244 MET A O    1 
ATOM   3785 C  CB   . MET A 1 244 ? 18.33600  -22.67000 30.66100 1.000 51.71410  ? 244 MET A CB   1 
ATOM   3786 C  CG   . MET A 1 244 ? 18.98000  -23.97800 30.23200 1.000 49.76123  ? 244 MET A CG   1 
ATOM   3787 S  SD   . MET A 1 244 ? 19.55300  -24.95000 31.64200 1.000 49.76913  ? 244 MET A SD   1 
ATOM   3788 C  CE   . MET A 1 244 ? 20.34400  -26.31900 30.80400 1.000 52.76685  ? 244 MET A CE   1 
ATOM   3789 H  H    . MET A 1 244 ? 16.58600  -20.68300 30.55100 1.000 55.87000  ? 244 MET A H    1 
ATOM   3790 H  HA   . MET A 1 244 ? 18.51800  -21.65000 28.89700 1.000 55.36000  ? 244 MET A HA   1 
ATOM   3791 H  HB2  . MET A 1 244 ? 19.00800  -22.15000 31.12800 1.000 62.17000  ? 244 MET A HB2  1 
ATOM   3792 H  HB3  . MET A 1 244 ? 17.60600  -22.88500 31.26300 1.000 62.17000  ? 244 MET A HB3  1 
ATOM   3793 H  HG2  . MET A 1 244 ? 18.33000  -24.50800 29.74400 1.000 59.83000  ? 244 MET A HG2  1 
ATOM   3794 H  HG3  . MET A 1 244 ? 19.74400  -23.78600 29.66700 1.000 59.83000  ? 244 MET A HG3  1 
ATOM   3795 H  HE1  . MET A 1 244 ? 20.77800  -26.88500 31.46200 1.000 63.43000  ? 244 MET A HE1  1 
ATOM   3796 H  HE2  . MET A 1 244 ? 19.67200  -26.82700 30.32400 1.000 63.43000  ? 244 MET A HE2  1 
ATOM   3797 H  HE3  . MET A 1 244 ? 21.00300  -25.97200 30.18200 1.000 63.43000  ? 244 MET A HE3  1 
ATOM   3798 N  N    . MET A 1 245 ? 16.89700  -22.81500 27.48400 1.000 48.20841  ? 245 MET A N    1 
ATOM   3799 C  CA   . MET A 1 245 ? 15.97200  -23.57200 26.65600 1.000 49.58752  ? 245 MET A CA   1 
ATOM   3800 C  C    . MET A 1 245 ? 16.59500  -24.93000 26.37200 1.000 50.28234  ? 245 MET A C    1 
ATOM   3801 O  O    . MET A 1 245 ? 17.73500  -25.00500 25.90100 1.000 51.13245  ? 245 MET A O    1 
ATOM   3802 C  CB   . MET A 1 245 ? 15.67400  -22.83200 25.35200 1.000 48.94008  ? 245 MET A CB   1 
ATOM   3803 C  CG   . MET A 1 245 ? 15.12700  -21.42500 25.55300 1.000 52.26942  ? 245 MET A CG   1 
ATOM   3804 S  SD   . MET A 1 245 ? 13.58400  -21.36800 26.48500 1.000 52.49840  ? 245 MET A SD   1 
ATOM   3805 C  CE   . MET A 1 245 ? 12.47700  -22.23500 25.37500 1.000 53.01951  ? 245 MET A CE   1 
ATOM   3806 H  H    . MET A 1 245 ? 17.58800  -22.53700 27.05600 1.000 57.96000  ? 245 MET A H    1 
ATOM   3807 H  HA   . MET A 1 245 ? 15.12800  -23.69200 27.11900 1.000 59.62000  ? 245 MET A HA   1 
ATOM   3808 H  HB2  . MET A 1 245 ? 16.49500  -22.76000 24.84100 1.000 58.84000  ? 245 MET A HB2  1 
ATOM   3809 H  HB3  . MET A 1 245 ? 15.01500  -23.33700 24.85200 1.000 58.84000  ? 245 MET A HB3  1 
ATOM   3810 H  HG2  . MET A 1 245 ? 15.78400  -20.90100 26.03700 1.000 62.83000  ? 245 MET A HG2  1 
ATOM   3811 H  HG3  . MET A 1 245 ? 14.96100  -21.02800 24.68400 1.000 62.83000  ? 245 MET A HG3  1 
ATOM   3812 H  HE1  . MET A 1 245 ? 11.57700  -22.19900 25.73500 1.000 63.74000  ? 245 MET A HE1  1 
ATOM   3813 H  HE2  . MET A 1 245 ? 12.50300  -21.80700 24.50500 1.000 63.74000  ? 245 MET A HE2  1 
ATOM   3814 H  HE3  . MET A 1 245 ? 12.76600  -23.15800 25.29800 1.000 63.74000  ? 245 MET A HE3  1 
ATOM   3815 N  N    . SER A 1 246 ? 15.85700  -25.99400 26.67200 1.000 49.00324  ? 246 SER A N    1 
ATOM   3816 C  CA   . SER A 1 246 ? 16.35200  -27.35100 26.51000 1.000 54.03279  ? 246 SER A CA   1 
ATOM   3817 C  C    . SER A 1 246 ? 15.34100  -28.17600 25.73100 1.000 54.43811  ? 246 SER A C    1 
ATOM   3818 O  O    . SER A 1 246 ? 14.16600  -27.81600 25.61700 1.000 55.76984  ? 246 SER A O    1 
ATOM   3819 C  CB   . SER A 1 246 ? 16.63600  -28.00800 27.86700 1.000 51.42459  ? 246 SER A CB   1 
ATOM   3820 O  OG   . SER A 1 246 ? 17.38400  -27.13900 28.70000 1.000 53.39588  ? 246 SER A OG   1 
ATOM   3821 H  H    . SER A 1 246 ? 15.05300  -25.95200 26.97500 1.000 58.92000  ? 246 SER A H    1 
ATOM   3822 H  HA   . SER A 1 246 ? 17.17900  -27.33400 26.00200 1.000 64.95000  ? 246 SER A HA   1 
ATOM   3823 H  HB2  . SER A 1 246 ? 15.79300  -28.21300 28.30100 1.000 61.82000  ? 246 SER A HB2  1 
ATOM   3824 H  HB3  . SER A 1 246 ? 17.14200  -28.82300 27.72400 1.000 61.82000  ? 246 SER A HB3  1 
ATOM   3825 H  HG   . SER A 1 246 ? 17.51500  -27.50000 29.44700 1.000 64.19000  ? 246 SER A HG   1 
ATOM   3826 N  N    . ALA A 1 247 ? 15.81400  -29.29200 25.19500 1.000 54.61181  ? 247 ALA A N    1 
ATOM   3827 C  CA   . ALA A 1 247 ? 14.99000  -30.18400 24.39300 1.000 55.44349  ? 247 ALA A CA   1 
ATOM   3828 C  C    . ALA A 1 247 ? 15.79100  -31.45000 24.10900 1.000 57.34635  ? 247 ALA A C    1 
ATOM   3829 O  O    . ALA A 1 247 ? 17.02300  -31.43200 24.17300 1.000 58.00169  ? 247 ALA A O    1 
ATOM   3830 C  CB   . ALA A 1 247 ? 14.55700  -29.51500 23.07800 1.000 55.12766  ? 247 ALA A CB   1 
ATOM   3831 H  H    . ALA A 1 247 ? 16.62700  -29.56000 25.28400 1.000 65.65000  ? 247 ALA A H    1 
ATOM   3832 H  HA   . ALA A 1 247 ? 14.19400  -30.43000 24.88900 1.000 66.65000  ? 247 ALA A HA   1 
ATOM   3833 H  HB1  . ALA A 1 247 ? 14.03500  -30.14700 22.55900 1.000 66.27000  ? 247 ALA A HB1  1 
ATOM   3834 H  HB2  . ALA A 1 247 ? 14.02200  -28.73300 23.28400 1.000 66.27000  ? 247 ALA A HB2  1 
ATOM   3835 H  HB3  . ALA A 1 247 ? 15.34900  -29.25300 22.58200 1.000 66.27000  ? 247 ALA A HB3  1 
ATOM   3836 N  N    . PRO A 1 248 ? 15.11500  -32.55400 23.80100 1.000 57.79114  ? 248 PRO A N    1 
ATOM   3837 C  CA   . PRO A 1 248 ? 15.82900  -33.77800 23.42400 1.000 62.50223  ? 248 PRO A CA   1 
ATOM   3838 C  C    . PRO A 1 248 ? 16.75700  -33.52000 22.25100 1.000 65.60260  ? 248 PRO A C    1 
ATOM   3839 O  O    . PRO A 1 248 ? 16.41800  -32.74700 21.34200 1.000 60.39935  ? 248 PRO A O    1 
ATOM   3840 C  CB   . PRO A 1 248 ? 14.69800  -34.74700 23.04500 1.000 62.48644  ? 248 PRO A CB   1 
ATOM   3841 C  CG   . PRO A 1 248 ? 13.50700  -34.24400 23.78200 1.000 62.57066  ? 248 PRO A CG   1 
ATOM   3842 C  CD   . PRO A 1 248 ? 13.65400  -32.75000 23.82400 1.000 61.39947  ? 248 PRO A CD   1 
ATOM   3843 H  HA   . PRO A 1 248 ? 16.33100  -34.13800 24.17200 1.000 75.12000  ? 248 PRO A HA   1 
ATOM   3844 H  HB2  . PRO A 1 248 ? 14.55000  -34.72400 22.08600 1.000 75.10000  ? 248 PRO A HB2  1 
ATOM   3845 H  HB3  . PRO A 1 248 ? 14.92600  -35.64700 23.32400 1.000 75.10000  ? 248 PRO A HB3  1 
ATOM   3846 H  HG2  . PRO A 1 248 ? 12.69900  -34.49600 23.30900 1.000 75.20000  ? 248 PRO A HG2  1 
ATOM   3847 H  HG3  . PRO A 1 248 ? 13.49700  -34.61400 24.67800 1.000 75.20000  ? 248 PRO A HG3  1 
ATOM   3848 H  HD2  . PRO A 1 248 ? 13.23800  -32.34000 23.05000 1.000 73.79000  ? 248 PRO A HD2  1 
ATOM   3849 H  HD3  . PRO A 1 248 ? 13.27000  -32.38800 24.63800 1.000 73.79000  ? 248 PRO A HD3  1 
ATOM   3850 N  N    . PRO A 1 249 ? 17.93600  -34.14100 22.23500 1.000 66.33690  ? 249 PRO A N    1 
ATOM   3851 C  CA   . PRO A 1 249 ? 18.90100  -33.86200 21.16400 1.000 61.34946  ? 249 PRO A CA   1 
ATOM   3852 C  C    . PRO A 1 249 ? 18.26900  -33.97700 19.78500 1.000 67.40808  ? 249 PRO A C    1 
ATOM   3853 O  O    . PRO A 1 249 ? 17.53400  -34.92200 19.49200 1.000 70.29264  ? 249 PRO A O    1 
ATOM   3854 C  CB   . PRO A 1 249 ? 19.98500  -34.92500 21.37900 1.000 66.48692  ? 249 PRO A CB   1 
ATOM   3855 C  CG   . PRO A 1 249 ? 19.88600  -35.29500 22.81500 1.000 68.47400  ? 249 PRO A CG   1 
ATOM   3856 C  CD   . PRO A 1 249 ? 18.45200  -35.11600 23.21500 1.000 66.74484  ? 249 PRO A CD   1 
ATOM   3857 H  HA   . PRO A 1 249 ? 19.28000  -32.97600 21.27400 1.000 73.73000  ? 249 PRO A HA   1 
ATOM   3858 H  HB2  . PRO A 1 249 ? 19.81300  -35.69100 20.81000 1.000 79.90000  ? 249 PRO A HB2  1 
ATOM   3859 H  HB3  . PRO A 1 249 ? 20.85700  -34.55100 21.17600 1.000 79.90000  ? 249 PRO A HB3  1 
ATOM   3860 H  HG2  . PRO A 1 249 ? 20.15700  -36.22000 22.92900 1.000 82.28000  ? 249 PRO A HG2  1 
ATOM   3861 H  HG3  . PRO A 1 249 ? 20.45900  -34.71400 23.33900 1.000 82.28000  ? 249 PRO A HG3  1 
ATOM   3862 H  HD2  . PRO A 1 249 ? 17.97000  -35.95600 23.15100 1.000 80.21000  ? 249 PRO A HD2  1 
ATOM   3863 H  HD3  . PRO A 1 249 ? 18.38800  -34.76500 24.11700 1.000 80.21000  ? 249 PRO A HD3  1 
ATOM   3864 N  N    . ALA A 1 250 ? 18.55900  -32.99600 18.93500 1.000 63.28917  ? 250 ALA A N    1 
ATOM   3865 C  CA   . ALA A 1 250 ? 18.02800  -32.97600 17.58200 1.000 68.71350  ? 250 ALA A CA   1 
ATOM   3866 C  C    . ALA A 1 250 ? 18.84400  -31.99500 16.75600 1.000 64.85251  ? 250 ALA A C    1 
ATOM   3867 O  O    . ALA A 1 250 ? 19.34400  -30.99400 17.27600 1.000 59.87034  ? 250 ALA A O    1 
ATOM   3868 C  CB   . ALA A 1 250 ? 16.54500  -32.58900 17.56400 1.000 66.67378  ? 250 ALA A CB   1 
ATOM   3869 H  H    . ALA A 1 250 ? 19.06500  -32.32700 19.12200 1.000 76.06000  ? 250 ALA A H    1 
ATOM   3870 H  HA   . ALA A 1 250 ? 18.11300  -33.85700 17.18500 1.000 82.57000  ? 250 ALA A HA   1 
ATOM   3871 H  HB1  . ALA A 1 250 ? 16.23000  -32.58400 16.64700 1.000 80.12000  ? 250 ALA A HB1  1 
ATOM   3872 H  HB2  . ALA A 1 250 ? 16.04300  -33.23700 18.08300 1.000 80.12000  ? 250 ALA A HB2  1 
ATOM   3873 H  HB3  . ALA A 1 250 ? 16.44500  -31.70600 17.95300 1.000 80.12000  ? 250 ALA A HB3  1 
ATOM   3874 N  N    . GLN A 1 251 ? 18.97900  -32.29800 15.46700 1.000 61.80741  ? 251 GLN A N    1 
ATOM   3875 C  CA   . GLN A 1 251 ? 19.69400  -31.41100 14.56100 1.000 63.60236  ? 251 GLN A CA   1 
ATOM   3876 C  C    . GLN A 1 251 ? 19.12000  -30.00300 14.64900 1.000 65.62103  ? 251 GLN A C    1 
ATOM   3877 O  O    . GLN A 1 251 ? 17.90900  -29.80200 14.52000 1.000 65.53944  ? 251 GLN A O    1 
ATOM   3878 C  CB   . GLN A 1 251 ? 19.60400  -31.93900 13.12900 1.000 65.53681  ? 251 GLN A CB   1 
ATOM   3879 C  CG   . GLN A 1 251 ? 20.41700  -33.20100 12.89200 1.000 67.46598  ? 251 GLN A CG   1 
ATOM   3880 C  CD   . GLN A 1 251 ? 21.89900  -32.99300 13.13000 1.000 71.65070  ? 251 GLN A CD   1 
ATOM   3881 O  OE1  . GLN A 1 251 ? 22.55200  -32.23100 12.41700 1.000 76.93554  ? 251 GLN A OE1  1 
ATOM   3882 N  NE2  . GLN A 1 251 ? 22.43800  -33.66500 14.14200 1.000 72.47448  ? 251 GLN A NE2  1 
ATOM   3883 H  H    . GLN A 1 251 ? 18.66600  -33.00900 15.09600 1.000 74.28000  ? 251 GLN A H    1 
ATOM   3884 H  HA   . GLN A 1 251 ? 20.63200  -31.37800 14.80600 1.000 76.43000  ? 251 GLN A HA   1 
ATOM   3885 H  HB2  . GLN A 1 251 ? 18.67700  -32.14100 12.92900 1.000 78.76000  ? 251 GLN A HB2  1 
ATOM   3886 H  HB3  . GLN A 1 251 ? 19.93300  -31.25600 12.52400 1.000 78.76000  ? 251 GLN A HB3  1 
ATOM   3887 H  HG2  . GLN A 1 251 ? 20.11000  -33.89400 13.49700 1.000 81.07000  ? 251 GLN A HG2  1 
ATOM   3888 H  HG3  . GLN A 1 251 ? 20.29700  -33.48700 11.97300 1.000 81.07000  ? 251 GLN A HG3  1 
ATOM   3889 H  HE21 . GLN A 1 251 ? 21.94800  -34.18400 14.62200 1.000 87.08000  ? 251 GLN A HE21 1 
ATOM   3890 H  HE22 . GLN A 1 251 ? 23.27500  -33.58000 14.31800 1.000 87.08000  ? 251 GLN A HE22 1 
ATOM   3891 N  N    . TYR A 1 252 ? 19.99700  -29.02900 14.87700 1.000 63.16020  ? 252 TYR A N    1 
ATOM   3892 C  CA   . TYR A 1 252 ? 19.57300  -27.66100 15.13100 1.000 58.48070  ? 252 TYR A CA   1 
ATOM   3893 C  C    . TYR A 1 252 ? 20.69000  -26.71200 14.72900 1.000 61.35999  ? 252 TYR A C    1 
ATOM   3894 O  O    . TYR A 1 252 ? 21.86800  -26.99100 14.97200 1.000 60.29934  ? 252 TYR A O    1 
ATOM   3895 C  CB   . TYR A 1 252 ? 19.20700  -27.47400 16.60700 1.000 61.66792  ? 252 TYR A CB   1 
ATOM   3896 C  CG   . TYR A 1 252 ? 18.62700  -26.12100 16.94100 1.000 57.64902  ? 252 TYR A CG   1 
ATOM   3897 C  CD1  . TYR A 1 252 ? 17.26600  -25.87500 16.81300 1.000 58.94654  ? 252 TYR A CD1  1 
ATOM   3898 C  CD2  . TYR A 1 252 ? 19.43900  -25.09200 17.39600 1.000 56.59100  ? 252 TYR A CD2  1 
ATOM   3899 C  CE1  . TYR A 1 252 ? 16.73200  -24.63700 17.12400 1.000 59.41765  ? 252 TYR A CE1  1 
ATOM   3900 C  CE2  . TYR A 1 252 ? 18.91600  -23.85400 17.70900 1.000 57.18580  ? 252 TYR A CE2  1 
ATOM   3901 C  CZ   . TYR A 1 252 ? 17.56300  -23.63100 17.57300 1.000 58.93338  ? 252 TYR A CZ   1 
ATOM   3902 O  OH   . TYR A 1 252 ? 17.04300  -22.39600 17.88500 1.000 57.80167  ? 252 TYR A OH   1 
ATOM   3903 H  H    . TYR A 1 252 ? 20.85000  -29.13900 14.88900 1.000 75.90000  ? 252 TYR A H    1 
ATOM   3904 H  HA   . TYR A 1 252 ? 18.79500  -27.44600 14.59200 1.000 70.29000  ? 252 TYR A HA   1 
ATOM   3905 H  HB2  . TYR A 1 252 ? 18.54800  -28.14300 16.85000 1.000 74.12000  ? 252 TYR A HB2  1 
ATOM   3906 H  HB3  . TYR A 1 252 ? 20.00900  -27.58800 17.14100 1.000 74.12000  ? 252 TYR A HB3  1 
ATOM   3907 H  HD1  . TYR A 1 252 ? 16.70400  -26.55400 16.51500 1.000 70.85000  ? 252 TYR A HD1  1 
ATOM   3908 H  HD2  . TYR A 1 252 ? 20.35200  -25.24000 17.49200 1.000 68.02000  ? 252 TYR A HD2  1 
ATOM   3909 H  HE1  . TYR A 1 252 ? 15.81900  -24.48400 17.03000 1.000 71.41000  ? 252 TYR A HE1  1 
ATOM   3910 H  HE2  . TYR A 1 252 ? 19.47400  -23.17400 18.01100 1.000 68.74000  ? 252 TYR A HE2  1 
ATOM   3911 H  HH   . TYR A 1 252 ? 17.65200  -21.89100 18.16700 1.000 69.48000  ? 252 TYR A HH   1 
ATOM   3912 N  N    . GLU A 1 253 ? 20.30900  -25.59300 14.11800 1.000 61.14154  ? 253 GLU A N    1 
ATOM   3913 C  CA   . GLU A 1 253 ? 21.25300  -24.61300 13.59400 1.000 65.56839  ? 253 GLU A CA   1 
ATOM   3914 C  C    . GLU A 1 253 ? 21.40300  -23.47100 14.59100 1.000 59.28079  ? 253 GLU A C    1 
ATOM   3915 O  O    . GLU A 1 253 ? 20.41000  -22.84700 14.98100 1.000 59.28342  ? 253 GLU A O    1 
ATOM   3916 C  CB   . GLU A 1 253 ? 20.77900  -24.08900 12.23800 1.000 69.75047  ? 253 GLU A CB   1 
ATOM   3917 C  CG   . GLU A 1 253 ? 21.80000  -23.25000 11.48800 1.000 74.92214  ? 253 GLU A CG   1 
ATOM   3918 C  CD   . GLU A 1 253 ? 21.21800  -22.61700 10.23500 1.000 90.07659  ? 253 GLU A CD   1 
ATOM   3919 O  OE1  . GLU A 1 253 ? 20.53500  -23.33100 9.46900  1.000 86.95779  ? 253 GLU A OE1  1 
ATOM   3920 O  OE2  . GLU A 1 253 ? 21.44100  -21.40800 10.01600 1.000 90.03711  ? 253 GLU A OE2  1 
ATOM   3921 H  H    . GLU A 1 253 ? 19.48700  -25.37400 13.99200 1.000 73.48000  ? 253 GLU A H    1 
ATOM   3922 H  HA   . GLU A 1 253 ? 22.12200  -25.02800 13.48000 1.000 78.80000  ? 253 GLU A HA   1 
ATOM   3923 H  HB2  . GLU A 1 253 ? 20.55400  -24.84700 11.67600 1.000 83.81000  ? 253 GLU A HB2  1 
ATOM   3924 H  HB3  . GLU A 1 253 ? 19.99400  -23.53600 12.37900 1.000 83.81000  ? 253 GLU A HB3  1 
ATOM   3925 H  HG2  . GLU A 1 253 ? 22.11400  -22.53900 12.06700 1.000 90.02000  ? 253 GLU A HG2  1 
ATOM   3926 H  HG3  . GLU A 1 253 ? 22.54300  -23.81500 11.22300 1.000 90.02000  ? 253 GLU A HG3  1 
ATOM   3927 N  N    . LEU A 1 254 ? 22.64200  -23.20200 15.00200 1.000 58.59650  ? 254 LEU A N    1 
ATOM   3928 C  CA   . LEU A 1 254 ? 22.95600  -22.10400 15.91100 1.000 62.19693  ? 254 LEU A CA   1 
ATOM   3929 C  C    . LEU A 1 254 ? 23.53000  -20.95600 15.08800 1.000 62.21009  ? 254 LEU A C    1 
ATOM   3930 O  O    . LEU A 1 254 ? 24.63000  -21.07000 14.53700 1.000 59.28079  ? 254 LEU A O    1 
ATOM   3931 C  CB   . LEU A 1 254 ? 23.94100  -22.54800 16.99100 1.000 53.38008  ? 254 LEU A CB   1 
ATOM   3932 C  CG   . LEU A 1 254 ? 23.48500  -23.66800 17.92600 1.000 57.45689  ? 254 LEU A CG   1 
ATOM   3933 C  CD1  . LEU A 1 254 ? 24.64700  -24.17000 18.77600 1.000 52.35628  ? 254 LEU A CD1  1 
ATOM   3934 C  CD2  . LEU A 1 254 ? 22.34200  -23.19700 18.81000 1.000 55.76721  ? 254 LEU A CD2  1 
ATOM   3935 H  H    . LEU A 1 254 ? 23.33300  -23.65300 14.76100 1.000 70.43000  ? 254 LEU A H    1 
ATOM   3936 H  HA   . LEU A 1 254 ? 22.14300  -21.80500 16.34800 1.000 74.75000  ? 254 LEU A HA   1 
ATOM   3937 H  HB2  . LEU A 1 254 ? 24.74800  -22.85800 16.54900 1.000 64.17000  ? 254 LEU A HB2  1 
ATOM   3938 H  HB3  . LEU A 1 254 ? 24.14200  -21.77900 17.54600 1.000 64.17000  ? 254 LEU A HB3  1 
ATOM   3939 H  HG   . LEU A 1 254 ? 23.16400  -24.41000 17.39000 1.000 69.06000  ? 254 LEU A HG   1 
ATOM   3940 H  HD11 . LEU A 1 254 ? 24.32900  -24.87700 19.36100 1.000 62.94000  ? 254 LEU A HD11 1 
ATOM   3941 H  HD12 . LEU A 1 254 ? 25.34100  -24.51300 18.19200 1.000 62.94000  ? 254 LEU A HD12 1 
ATOM   3942 H  HD13 . LEU A 1 254 ? 24.99200  -23.43400 19.30500 1.000 62.94000  ? 254 LEU A HD13 1 
ATOM   3943 H  HD21 . LEU A 1 254 ? 22.06800  -23.92600 19.38900 1.000 67.04000  ? 254 LEU A HD21 1 
ATOM   3944 H  HD22 . LEU A 1 254 ? 22.64500  -22.44600 19.34500 1.000 67.04000  ? 254 LEU A HD22 1 
ATOM   3945 H  HD23 . LEU A 1 254 ? 21.60000  -22.92400 18.24800 1.000 67.04000  ? 254 LEU A HD23 1 
ATOM   3946 N  N    . LYS A 1 255 ? 22.79100  -19.85400 15.00700 1.000 64.24718  ? 255 LYS A N    1 
ATOM   3947 C  CA   . LYS A 1 255 ? 23.22700  -18.70000 14.23300 1.000 70.71374  ? 255 LYS A CA   1 
ATOM   3948 C  C    . LYS A 1 255 ? 23.97000  -17.71400 15.12600 1.000 67.44230  ? 255 LYS A C    1 
ATOM   3949 O  O    . LYS A 1 255 ? 23.61300  -17.51400 16.29100 1.000 61.94690  ? 255 LYS A O    1 
ATOM   3950 C  CB   . LYS A 1 255 ? 22.03800  -18.01000 13.56300 1.000 69.14513  ? 255 LYS A CB   1 
ATOM   3951 C  CG   . LYS A 1 255 ? 21.56300  -18.67500 12.27000 1.000 78.38308  ? 255 LYS A CG   1 
ATOM   3952 C  CD   . LYS A 1 255 ? 22.67700  -18.79800 11.22600 1.000 89.85288  ? 255 LYS A CD   1 
ATOM   3953 C  CE   . LYS A 1 255 ? 22.45500  -17.89000 10.02500 1.000 90.47137  ? 255 LYS A CE   1 
ATOM   3954 N  NZ   . LYS A 1 255 ? 23.75200  -17.40900 9.47100  1.000 85.04704  ? 255 LYS A NZ   1 
ATOM   3955 H  H    . LYS A 1 255 ? 22.03000  -19.75000 15.39400 1.000 77.21000  ? 255 LYS A H    1 
ATOM   3956 H  HA   . LYS A 1 255 ? 23.83300  -18.99600 13.53600 1.000 84.97000  ? 255 LYS A HA   1 
ATOM   3957 H  HB2  . LYS A 1 255 ? 21.29200  -18.00900 14.18300 1.000 83.09000  ? 255 LYS A HB2  1 
ATOM   3958 H  HB3  . LYS A 1 255 ? 22.29100  -17.09800 13.34800 1.000 83.09000  ? 255 LYS A HB3  1 
ATOM   3959 H  HG2  . LYS A 1 255 ? 21.24200  -19.56700 12.47300 1.000 94.17000  ? 255 LYS A HG2  1 
ATOM   3960 H  HG3  . LYS A 1 255 ? 20.84800  -18.14500 11.88500 1.000 94.17000  ? 255 LYS A HG3  1 
ATOM   3961 H  HD2  . LYS A 1 255 ? 23.52300  -18.55500 11.63400 1.000 107.93000 ? 255 LYS A HD2  1 
ATOM   3962 H  HD3  . LYS A 1 255 ? 22.71300  -19.71400 10.90800 1.000 107.93000 ? 255 LYS A HD3  1 
ATOM   3963 H  HE2  . LYS A 1 255 ? 21.98800  -18.38100 9.33100  1.000 108.68000 ? 255 LYS A HE2  1 
ATOM   3964 H  HE3  . LYS A 1 255 ? 21.93200  -17.11900 10.29500 1.000 108.68000 ? 255 LYS A HE3  1 
ATOM   3965 H  HZ1  . LYS A 1 255 ? 23.60600  -16.87300 8.77600  1.000 102.17000 ? 255 LYS A HZ1  1 
ATOM   3966 H  HZ2  . LYS A 1 255 ? 24.20100  -16.95800 10.09400 1.000 102.17000 ? 255 LYS A HZ2  1 
ATOM   3967 H  HZ3  . LYS A 1 255 ? 24.24500  -18.10000 9.20400  1.000 102.17000 ? 255 LYS A HZ3  1 
ATOM   3968 N  N    . HIS A 1 256 ? 25.00600  -17.09900 14.56200 1.000 64.62354  ? 256 HIS A N    1 
ATOM   3969 C  CA   . HIS A 1 256 ? 25.86400  -16.20200 15.32100 1.000 66.49218  ? 256 HIS A CA   1 
ATOM   3970 C  C    . HIS A 1 256 ? 25.09100  -14.96200 15.75400 1.000 63.40760  ? 256 HIS A C    1 
ATOM   3971 O  O    . HIS A 1 256 ? 24.42200  -14.31800 14.94100 1.000 65.05254  ? 256 HIS A O    1 
ATOM   3972 C  CB   . HIS A 1 256 ? 27.07600  -15.81300 14.47200 1.000 62.75489  ? 256 HIS A CB   1 
ATOM   3973 C  CG   . HIS A 1 256 ? 27.88100  -14.68400 15.03500 1.000 64.34982  ? 256 HIS A CG   1 
ATOM   3974 N  ND1  . HIS A 1 256 ? 28.47900  -13.73200 14.23800 1.000 70.45055  ? 256 HIS A ND1  1 
ATOM   3975 C  CD2  . HIS A 1 256 ? 28.20500  -14.36400 16.31000 1.000 71.18485  ? 256 HIS A CD2  1 
ATOM   3976 C  CE1  . HIS A 1 256 ? 29.12700  -12.86700 14.99800 1.000 69.44254  ? 256 HIS A CE1  1 
ATOM   3977 N  NE2  . HIS A 1 256 ? 28.97600  -13.22700 16.25900 1.000 71.37961  ? 256 HIS A NE2  1 
ATOM   3978 H  H    . HIS A 1 256 ? 25.23300  -17.18600 13.73700 1.000 77.66000  ? 256 HIS A H    1 
ATOM   3979 H  HA   . HIS A 1 256 ? 26.17900  -16.64700 16.12300 1.000 79.90000  ? 256 HIS A HA   1 
ATOM   3980 H  HB2  . HIS A 1 256 ? 27.66100  -16.58300 14.39600 1.000 75.42000  ? 256 HIS A HB2  1 
ATOM   3981 H  HB3  . HIS A 1 256 ? 26.76500  -15.54400 13.59400 1.000 75.42000  ? 256 HIS A HB3  1 
ATOM   3982 H  HD2  . HIS A 1 256 ? 27.95300  -14.82600 17.07600 1.000 85.54000  ? 256 HIS A HD2  1 
ATOM   3983 H  HE1  . HIS A 1 256 ? 29.60600  -12.13000 14.69600 1.000 83.45000  ? 256 HIS A HE1  1 
ATOM   3984 H  HE2  . HIS A 1 256 ? 29.30700  -12.81800 16.93900 1.000 85.77000  ? 256 HIS A HE2  1 
ATOM   3985 N  N    . GLY A 1 257 ? 25.17900  -14.63300 17.04200 1.000 68.18712  ? 257 GLY A N    1 
ATOM   3986 C  CA   . GLY A 1 257 ? 24.57600  -13.42900 17.57200 1.000 59.13341  ? 257 GLY A CA   1 
ATOM   3987 C  C    . GLY A 1 257 ? 23.16000  -13.57600 18.08200 1.000 57.24107  ? 257 GLY A C    1 
ATOM   3988 O  O    . GLY A 1 257 ? 22.58900  -12.58600 18.55700 1.000 58.42543  ? 257 GLY A O    1 
ATOM   3989 H  H    . GLY A 1 257 ? 25.59100  -15.10300 17.63200 1.000 81.94000  ? 257 GLY A H    1 
ATOM   3990 H  HA2  . GLY A 1 257 ? 25.12100  -13.11100 18.30800 1.000 71.07000  ? 257 GLY A HA2  1 
ATOM   3991 H  HA3  . GLY A 1 257 ? 24.56700  -12.75700 16.87200 1.000 71.07000  ? 257 GLY A HA3  1 
ATOM   3992 N  N    . THR A 1 258 ? 22.57300  -14.77000 18.00500 1.000 55.46981  ? 258 THR A N    1 
ATOM   3993 C  CA   . THR A 1 258 ? 21.19900  -14.99800 18.43300 1.000 55.52245  ? 258 THR A CA   1 
ATOM   3994 C  C    . THR A 1 258 ? 21.11400  -15.73500 19.76300 1.000 55.83038  ? 258 THR A C    1 
ATOM   3995 O  O    . THR A 1 258 ? 20.01300  -16.08100 20.20100 1.000 51.23509  ? 258 THR A O    1 
ATOM   3996 C  CB   . THR A 1 258 ? 20.43400  -15.78500 17.36600 1.000 56.31728  ? 258 THR A CB   1 
ATOM   3997 O  OG1  . THR A 1 258 ? 21.27200  -16.82200 16.84100 1.000 58.93075  ? 258 THR A OG1  1 
ATOM   3998 C  CG2  . THR A 1 258 ? 19.99100  -14.86700 16.23600 1.000 61.23366  ? 258 THR A CG2  1 
ATOM   3999 H  H    . THR A 1 258 ? 22.96000  -15.47600 17.70100 1.000 66.68000  ? 258 THR A H    1 
ATOM   4000 H  HA   . THR A 1 258 ? 20.76900  -14.13400 18.53800 1.000 66.74000  ? 258 THR A HA   1 
ATOM   4001 H  HB   . THR A 1 258 ? 19.64100  -16.18100 17.76200 1.000 67.69000  ? 258 THR A HB   1 
ATOM   4002 H  HG1  . THR A 1 258 ? 20.86600  -17.24100 16.23700 1.000 70.83000  ? 258 THR A HG1  1 
ATOM   4003 H  HG21 . THR A 1 258 ? 19.51100  -15.37500 15.56400 1.000 73.59000  ? 258 THR A HG21 1 
ATOM   4004 H  HG22 . THR A 1 258 ? 19.40900  -14.17200 16.58200 1.000 73.59000  ? 258 THR A HG22 1 
ATOM   4005 H  HG23 . THR A 1 258 ? 20.76500  -14.45200 15.82300 1.000 73.59000  ? 258 THR A HG23 1 
ATOM   4006 N  N    . PHE A 1 259 ? 22.24700  -15.98200 20.41100 1.000 53.79066  ? 259 PHE A N    1 
ATOM   4007 C  CA   . PHE A 1 259 ? 22.26700  -16.73600 21.65500 1.000 51.06665  ? 259 PHE A CA   1 
ATOM   4008 C  C    . PHE A 1 259 ? 23.60600  -16.50200 22.33400 1.000 53.36956  ? 259 PHE A C    1 
ATOM   4009 O  O    . PHE A 1 259 ? 24.55200  -15.98800 21.73100 1.000 49.29802  ? 259 PHE A O    1 
ATOM   4010 C  CB   . PHE A 1 259 ? 22.03800  -18.22800 21.40400 1.000 49.70333  ? 259 PHE A CB   1 
ATOM   4011 C  CG   . PHE A 1 259 ? 23.21000  -18.91300 20.76900 1.000 53.39588  ? 259 PHE A CG   1 
ATOM   4012 C  CD1  . PHE A 1 259 ? 23.50700  -18.70700 19.43200 1.000 52.22731  ? 259 PHE A CD1  1 
ATOM   4013 C  CD2  . PHE A 1 259 ? 24.02300  -19.75200 21.51100 1.000 46.26081  ? 259 PHE A CD2  1 
ATOM   4014 C  CE1  . PHE A 1 259 ? 24.58900  -19.33000 18.84400 1.000 52.50893  ? 259 PHE A CE1  1 
ATOM   4015 C  CE2  . PHE A 1 259 ? 25.10800  -20.37900 20.92900 1.000 51.30615  ? 259 PHE A CE2  1 
ATOM   4016 C  CZ   . PHE A 1 259 ? 25.39100  -20.16800 19.59300 1.000 48.11366  ? 259 PHE A CZ   1 
ATOM   4017 H  H    . PHE A 1 259 ? 23.02300  -15.72100 20.14800 1.000 64.66000  ? 259 PHE A H    1 
ATOM   4018 H  HA   . PHE A 1 259 ? 21.56300  -16.41200 22.23800 1.000 61.40000  ? 259 PHE A HA   1 
ATOM   4019 H  HB2  . PHE A 1 259 ? 21.86200  -18.66500 22.25200 1.000 59.75000  ? 259 PHE A HB2  1 
ATOM   4020 H  HB3  . PHE A 1 259 ? 21.27600  -18.33300 20.81200 1.000 59.75000  ? 259 PHE A HB3  1 
ATOM   4021 H  HD1  . PHE A 1 259 ? 22.97000  -18.14200 18.92300 1.000 62.78000  ? 259 PHE A HD1  1 
ATOM   4022 H  HD2  . PHE A 1 259 ? 23.83800  -19.89600 22.41100 1.000 55.63000  ? 259 PHE A HD2  1 
ATOM   4023 H  HE1  . PHE A 1 259 ? 24.77800  -19.18600 17.94500 1.000 63.12000  ? 259 PHE A HE1  1 
ATOM   4024 H  HE2  . PHE A 1 259 ? 25.64700  -20.94200 21.43500 1.000 61.68000  ? 259 PHE A HE2  1 
ATOM   4025 H  HZ   . PHE A 1 259 ? 26.12100  -20.58900 19.19900 1.000 57.85000  ? 259 PHE A HZ   1 
ATOM   4026 N  N    . THR A 1 260 ? 23.67300  -16.89500 23.60400 1.000 50.36657  ? 260 THR A N    1 
ATOM   4027 C  CA   . THR A 1 260 ? 24.89000  -16.76700 24.39400 1.000 47.89258  ? 260 THR A CA   1 
ATOM   4028 C  C    . THR A 1 260 ? 25.78700  -17.99000 24.24900 1.000 47.22145  ? 260 THR A C    1 
ATOM   4029 O  O    . THR A 1 260 ? 26.97300  -17.86200 23.93000 1.000 49.82703  ? 260 THR A O    1 
ATOM   4030 C  CB   . THR A 1 260 ? 24.53200  -16.55500 25.86900 1.000 52.64579  ? 260 THR A CB   1 
ATOM   4031 O  OG1  . THR A 1 260 ? 23.40500  -15.67500 25.96600 1.000 56.00672  ? 260 THR A OG1  1 
ATOM   4032 C  CG2  . THR A 1 260 ? 25.71000  -15.97100 26.63100 1.000 54.73025  ? 260 THR A CG2  1 
ATOM   4033 H  H    . THR A 1 260 ? 23.01600  -17.24400 24.03600 1.000 60.55000  ? 260 THR A H    1 
ATOM   4034 H  HA   . THR A 1 260 ? 25.38300  -15.99100 24.08700 1.000 57.58000  ? 260 THR A HA   1 
ATOM   4035 H  HB   . THR A 1 260 ? 24.30800  -17.40800 26.27500 1.000 63.29000  ? 260 THR A HB   1 
ATOM   4036 H  HG1  . THR A 1 260 ? 23.15600  -15.61500 26.76500 1.000 67.32000  ? 260 THR A HG1  1 
ATOM   4037 H  HG21 . THR A 1 260 ? 25.44300  -15.75300 27.53800 1.000 65.79000  ? 260 THR A HG21 1 
ATOM   4038 H  HG22 . THR A 1 260 ? 26.43600  -16.61300 26.66200 1.000 65.79000  ? 260 THR A HG22 1 
ATOM   4039 H  HG23 . THR A 1 260 ? 26.02200  -15.16400 26.19200 1.000 65.79000  ? 260 THR A HG23 1 
ATOM   4040 N  N    . CYS A 1 261 ? 25.23600  -19.17700 24.48300 1.000 46.33713  ? 261 CYS A N    1 
ATOM   4041 C  CA   . CYS A 1 261 ? 26.00300  -20.41300 24.42100 1.000 45.40018  ? 261 CYS A CA   1 
ATOM   4042 C  C    . CYS A 1 261 ? 25.02700  -21.57800 24.46000 1.000 44.44480  ? 261 CYS A C    1 
ATOM   4043 O  O    . CYS A 1 261 ? 23.85400  -21.41500 24.80700 1.000 47.47148  ? 261 CYS A O    1 
ATOM   4044 C  CB   . CYS A 1 261 ? 27.01500  -20.50700 25.56700 1.000 50.35077  ? 261 CYS A CB   1 
ATOM   4045 S  SG   . CYS A 1 261 ? 26.27800  -20.72900 27.19800 1.000 48.49529  ? 261 CYS A SG   1 
ATOM   4046 H  H    . CYS A 1 261 ? 24.40800  -19.29300 24.68400 1.000 55.72000  ? 261 CYS A H    1 
ATOM   4047 H  HA   . CYS A 1 261 ? 26.49300  -20.45400 23.58500 1.000 54.59000  ? 261 CYS A HA   1 
ATOM   4048 H  HB2  . CYS A 1 261 ? 27.59800  -21.26500 25.40200 1.000 60.53000  ? 261 CYS A HB2  1 
ATOM   4049 H  HB3  . CYS A 1 261 ? 27.53400  -19.68800 25.58800 1.000 60.53000  ? 261 CYS A HB3  1 
ATOM   4050 H  HG   . CYS A 1 261 ? 27.15400  -20.80200 28.01500 1.000 58.31000  ? 261 CYS A HG   1 
ATOM   4051 N  N    . ALA A 1 262 ? 25.52800  -22.75500 24.09700 1.000 46.46873  ? 262 ALA A N    1 
ATOM   4052 C  CA   . ALA A 1 262 ? 24.68700  -23.93400 23.96500 1.000 46.36872  ? 262 ALA A CA   1 
ATOM   4053 C  C    . ALA A 1 262 ? 25.51700  -25.17100 24.26400 1.000 43.45258  ? 262 ALA A C    1 
ATOM   4054 O  O    . ALA A 1 262 ? 26.74900  -25.12700 24.29600 1.000 43.72630  ? 262 ALA A O    1 
ATOM   4055 C  CB   . ALA A 1 262 ? 24.07400  -24.03400 22.56100 1.000 50.02705  ? 262 ALA A CB   1 
ATOM   4056 H  H    . ALA A 1 262 ? 26.35800  -22.89500 23.92100 1.000 55.87000  ? 262 ALA A H    1 
ATOM   4057 H  HA   . ALA A 1 262 ? 23.96900  -23.87800 24.61500 1.000 55.75000  ? 262 ALA A HA   1 
ATOM   4058 H  HB1  . ALA A 1 262 ? 23.54600  -24.84600 22.50400 1.000 60.15000  ? 262 ALA A HB1  1 
ATOM   4059 H  HB2  . ALA A 1 262 ? 23.50900  -23.26100 22.40700 1.000 60.15000  ? 262 ALA A HB2  1 
ATOM   4060 H  HB3  . ALA A 1 262 ? 24.78800  -24.05700 21.90500 1.000 60.15000  ? 262 ALA A HB3  1 
ATOM   4061 N  N    . SER A 1 263 ? 24.82200  -26.28500 24.47600 1.000 43.53417  ? 263 SER A N    1 
ATOM   4062 C  CA   . SER A 1 263 ? 25.45200  -27.58000 24.67700 1.000 46.47136  ? 263 SER A CA   1 
ATOM   4063 C  C    . SER A 1 263 ? 25.00400  -28.54500 23.58800 1.000 50.87452  ? 263 SER A C    1 
ATOM   4064 O  O    . SER A 1 263 ? 23.81900  -28.60600 23.24300 1.000 51.70094  ? 263 SER A O    1 
ATOM   4065 C  CB   . SER A 1 263 ? 25.11500  -28.15000 26.05700 1.000 48.55845  ? 263 SER A CB   1 
ATOM   4066 O  OG   . SER A 1 263 ? 25.42500  -27.21200 27.07400 1.000 50.20865  ? 263 SER A OG   1 
ATOM   4067 H  H    . SER A 1 263 ? 23.96300  -26.31300 24.50800 1.000 52.35000  ? 263 SER A H    1 
ATOM   4068 H  HA   . SER A 1 263 ? 26.41500  -27.48500 24.61700 1.000 55.88000  ? 263 SER A HA   1 
ATOM   4069 H  HB2  . SER A 1 263 ? 24.16700  -28.35400 26.09200 1.000 58.38000  ? 263 SER A HB2  1 
ATOM   4070 H  HB3  . SER A 1 263 ? 25.63400  -28.95700 26.20100 1.000 58.38000  ? 263 SER A HB3  1 
ATOM   4071 H  HG   . SER A 1 263 ? 25.22100  -27.52600 27.82600 1.000 60.36000  ? 263 SER A HG   1 
ATOM   4072 N  N    . GLU A 1 264 ? 25.96600  -29.25000 23.00500 1.000 47.87942  ? 264 GLU A N    1 
ATOM   4073 C  CA   . GLU A 1 264 ? 25.71200  -30.28400 21.98700 1.000 49.72965  ? 264 GLU A CA   1 
ATOM   4074 C  C    . GLU A 1 264 ? 25.86300  -31.62600 22.69100 1.000 51.70357  ? 264 GLU A C    1 
ATOM   4075 O  O    . GLU A 1 264 ? 26.58400  -31.68900 23.63700 1.000 46.80561  ? 264 GLU A O    1 
ATOM   4076 C  CB   . GLU A 1 264 ? 26.71700  -30.14200 20.85200 1.000 56.12252  ? 264 GLU A CB   1 
ATOM   4077 C  CG   . GLU A 1 264 ? 26.61300  -31.22200 19.80200 1.000 60.07826  ? 264 GLU A CG   1 
ATOM   4078 C  CD   . GLU A 1 264 ? 27.64300  -31.07400 18.70200 1.000 67.04225  ? 264 GLU A CD   1 
ATOM   4079 O  OE1  . GLU A 1 264 ? 28.76600  -31.57700 18.87300 1.000 69.06091  ? 264 GLU A OE1  1 
ATOM   4080 O  OE2  . GLU A 1 264 ? 27.31400  -30.45400 17.68600 1.000 72.60607  ? 264 GLU A OE2  1 
ATOM   4081 H  H    . GLU A 1 264 ? 26.84400  -29.13800 23.17800 1.000 57.57000  ? 264 GLU A H    1 
ATOM   4082 H  HA   . GLU A 1 264 ? 24.80100  -30.19200 21.63500 1.000 59.79000  ? 264 GLU A HA   1 
ATOM   4083 H  HB2  . GLU A 1 264 ? 26.58300  -29.27100 20.42400 1.000 67.46000  ? 264 GLU A HB2  1 
ATOM   4084 H  HB3  . GLU A 1 264 ? 27.62000  -30.15400 21.23200 1.000 67.46000  ? 264 GLU A HB3  1 
ATOM   4085 H  HG2  . GLU A 1 264 ? 26.73000  -32.10000 20.21800 1.000 72.21000  ? 264 GLU A HG2  1 
ATOM   4086 H  HG3  . GLU A 1 264 ? 25.71900  -31.19600 19.40100 1.000 72.21000  ? 264 GLU A HG3  1 
ATOM   4087 N  N    . TYR A 1 265 ? 25.10100  -32.62300 22.31500 1.000 54.77236  ? 265 TYR A N    1 
ATOM   4088 C  CA   . TYR A 1 265 ? 25.20200  -33.97100 22.85500 1.000 55.15661  ? 265 TYR A CA   1 
ATOM   4089 C  C    . TYR A 1 265 ? 25.15600  -34.99000 21.72900 1.000 54.10912  ? 265 TYR A C    1 
ATOM   4090 O  O    . TYR A 1 265 ? 24.23700  -34.96800 20.90400 1.000 58.73599  ? 265 TYR A O    1 
ATOM   4091 C  CB   . TYR A 1 265 ? 24.08000  -34.26600 23.85300 1.000 52.79054  ? 265 TYR A CB   1 
ATOM   4092 C  CG   . TYR A 1 265 ? 24.24400  -35.60300 24.53700 1.000 56.08304  ? 265 TYR A CG   1 
ATOM   4093 C  CD1  . TYR A 1 265 ? 25.17400  -35.77300 25.55300 1.000 55.39875  ? 265 TYR A CD1  1 
ATOM   4094 C  CD2  . TYR A 1 265 ? 23.48300  -36.70000 24.15500 1.000 58.55965  ? 265 TYR A CD2  1 
ATOM   4095 C  CE1  . TYR A 1 265 ? 25.33500  -36.99300 26.17800 1.000 57.10948  ? 265 TYR A CE1  1 
ATOM   4096 C  CE2  . TYR A 1 265 ? 23.63700  -37.92600 24.77500 1.000 62.19167  ? 265 TYR A CE2  1 
ATOM   4097 C  CZ   . TYR A 1 265 ? 24.56300  -38.06600 25.78700 1.000 62.24694  ? 265 TYR A CZ   1 
ATOM   4098 O  OH   . TYR A 1 265 ? 24.72300  -39.28400 26.40800 1.000 60.33355  ? 265 TYR A OH   1 
ATOM   4099 H  H    . TYR A 1 265 ? 24.43100  -32.50700 21.78900 1.000 65.84000  ? 265 TYR A H    1 
ATOM   4100 H  HA   . TYR A 1 265 ? 26.05600  -34.05400 23.30800 1.000 66.30000  ? 265 TYR A HA   1 
ATOM   4101 H  HB2  . TYR A 1 265 ? 24.07500  -33.57800 24.53600 1.000 63.46000  ? 265 TYR A HB2  1 
ATOM   4102 H  HB3  . TYR A 1 265 ? 23.23200  -34.27200 23.38200 1.000 63.46000  ? 265 TYR A HB3  1 
ATOM   4103 H  HD1  . TYR A 1 265 ? 25.69900  -35.05200 25.81700 1.000 66.59000  ? 265 TYR A HD1  1 
ATOM   4104 H  HD2  . TYR A 1 265 ? 22.86000  -36.60900 23.47100 1.000 70.39000  ? 265 TYR A HD2  1 
ATOM   4105 H  HE1  . TYR A 1 265 ? 25.96000  -37.09100 26.86000 1.000 68.64000  ? 265 TYR A HE1  1 
ATOM   4106 H  HE2  . TYR A 1 265 ? 23.11800  -38.65200 24.51100 1.000 74.74000  ? 265 TYR A HE2  1 
ATOM   4107 H  HH   . TYR A 1 265 ? 24.17000  -39.83700 26.10100 1.000 72.51000  ? 265 TYR A HH   1 
ATOM   4108 N  N    . THR A 1 266 ? 26.13800  -35.88700 21.71200 1.000 53.99068  ? 266 THR A N    1 
ATOM   4109 C  CA   . THR A 1 266 ? 26.18600  -37.00600 20.78000 1.000 57.53585  ? 266 THR A CA   1 
ATOM   4110 C  C    . THR A 1 266 ? 26.19700  -38.29600 21.58800 1.000 62.15745  ? 266 THR A C    1 
ATOM   4111 O  O    . THR A 1 266 ? 27.05700  -38.48000 22.45600 1.000 65.16044  ? 266 THR A O    1 
ATOM   4112 C  CB   . THR A 1 266 ? 27.42000  -36.92000 19.87900 1.000 64.03926  ? 266 THR A CB   1 
ATOM   4113 O  OG1  . THR A 1 266 ? 27.38800  -35.69200 19.13900 1.000 65.73420  ? 266 THR A OG1  1 
ATOM   4114 C  CG2  . THR A 1 266 ? 27.46200  -38.08900 18.90600 1.000 58.94128  ? 266 THR A CG2  1 
ATOM   4115 H  H    . THR A 1 266 ? 26.80900  -35.86600 22.25000 1.000 64.90000  ? 266 THR A H    1 
ATOM   4116 H  HA   . THR A 1 266 ? 25.39900  -36.99900 20.21300 1.000 69.15000  ? 266 THR A HA   1 
ATOM   4117 H  HB   . THR A 1 266 ? 28.22000  -36.95100 20.42600 1.000 76.96000  ? 266 THR A HB   1 
ATOM   4118 H  HG1  . THR A 1 266 ? 28.06800  -35.63300 18.65100 1.000 78.99000  ? 266 THR A HG1  1 
ATOM   4119 H  HG21 . THR A 1 266 ? 28.22800  -38.00300 18.31600 1.000 70.84000  ? 266 THR A HG21 1 
ATOM   4120 H  HG22 . THR A 1 266 ? 27.53400  -38.92500 19.39400 1.000 70.84000  ? 266 THR A HG22 1 
ATOM   4121 H  HG23 . THR A 1 266 ? 26.65300  -38.10600 18.37100 1.000 70.84000  ? 266 THR A HG23 1 
ATOM   4122 N  N    . GLY A 1 267 ? 25.24200  -39.18000 21.30600 1.000 66.62904  ? 267 GLY A N    1 
ATOM   4123 C  CA   . GLY A 1 267 ? 25.14500  -40.44200 22.01200 1.000 72.91137  ? 267 GLY A CA   1 
ATOM   4124 C  C    . GLY A 1 267 ? 23.71200  -40.85200 22.27900 1.000 73.11929  ? 267 GLY A C    1 
ATOM   4125 O  O    . GLY A 1 267 ? 22.82900  -40.61100 21.44900 1.000 74.64053  ? 267 GLY A O    1 
ATOM   4126 H  H    . GLY A 1 267 ? 24.63700  -39.06600 20.70600 1.000 80.07000  ? 267 GLY A H    1 
ATOM   4127 H  HA2  . GLY A 1 267 ? 25.56800  -41.13700 21.48400 1.000 87.61000  ? 267 GLY A HA2  1 
ATOM   4128 H  HA3  . GLY A 1 267 ? 25.60400  -40.36900 22.86400 1.000 87.61000  ? 267 GLY A HA3  1 
ATOM   4129 N  N    . ASN A 1 268 ? 23.46700  -41.47000 23.42900 1.000 71.18222  ? 268 ASN A N    1 
ATOM   4130 C  CA   . ASN A 1 268 ? 22.12800  -41.91300 23.80200 1.000 69.91101  ? 268 ASN A CA   1 
ATOM   4131 C  C    . ASN A 1 268 ? 21.96500  -41.69600 25.30300 1.000 75.15901  ? 268 ASN A C    1 
ATOM   4132 O  O    . ASN A 1 268 ? 22.73400  -40.96600 25.93700 1.000 75.37219  ? 268 ASN A O    1 
ATOM   4133 C  CB   . ASN A 1 268 ? 21.90500  -43.37400 23.37400 1.000 74.15100  ? 268 ASN A CB   1 
ATOM   4134 C  CG   . ASN A 1 268 ? 22.91800  -44.32600 23.98500 1.000 75.92752  ? 268 ASN A CG   1 
ATOM   4135 O  OD1  . ASN A 1 268 ? 23.53100  -44.03000 25.01000 1.000 73.56408  ? 268 ASN A OD1  1 
ATOM   4136 N  ND2  . ASN A 1 268 ? 23.09600  -45.48100 23.35400 1.000 73.42196  ? 268 ASN A ND2  1 
ATOM   4137 H  H    . ASN A 1 268 ? 24.06800  -41.64600 24.01800 1.000 85.53000  ? 268 ASN A H    1 
ATOM   4138 H  HA   . ASN A 1 268 ? 21.48200  -41.35600 23.34000 1.000 84.01000  ? 268 ASN A HA   1 
ATOM   4139 H  HB2  . ASN A 1 268 ? 21.02100  -43.65500 23.65800 1.000 89.09000  ? 268 ASN A HB2  1 
ATOM   4140 H  HB3  . ASN A 1 268 ? 21.97900  -43.43500 22.40900 1.000 89.09000  ? 268 ASN A HB3  1 
ATOM   4141 H  HD21 . ASN A 1 268 ? 22.64800  -45.65400 22.64000 1.000 88.22000  ? 268 ASN A HD21 1 
ATOM   4142 H  HD22 . ASN A 1 268 ? 23.65800  -46.05500 23.65900 1.000 88.22000  ? 268 ASN A HD22 1 
ATOM   4143 N  N    . TYR A 1 269 ? 20.89000  -42.43900 25.86700 1.000 81.04393  ? 269 TYR A N    1 
ATOM   4144 C  CA   . TYR A 1 269 ? 20.59000  -42.25400 27.30400 1.000 85.53131  ? 269 TYR A CA   1 
ATOM   4145 C  C    . TYR A 1 269 ? 21.62100  -42.99300 28.16200 1.000 83.48369  ? 269 TYR A C    1 
ATOM   4146 O  O    . TYR A 1 269 ? 21.65100  -42.67800 29.35900 1.000 85.58395  ? 269 TYR A O    1 
ATOM   4147 C  CB   . TYR A 1 269 ? 19.17300  -42.70700 27.64300 1.000 91.50571  ? 269 TYR A CB   1 
ATOM   4148 C  CG   . TYR A 1 269 ? 18.41700  -41.70600 28.47500 1.000 85.46288  ? 269 TYR A CG   1 
ATOM   4149 C  CD1  . TYR A 1 269 ? 18.12500  -40.44900 27.97800 1.000 84.30748  ? 269 TYR A CD1  1 
ATOM   4150 C  CD2  . TYR A 1 269 ? 18.01700  -42.00300 29.76400 1.000 81.27817  ? 269 TYR A CD2  1 
ATOM   4151 C  CE1  . TYR A 1 269 ? 17.44300  -39.51500 28.73500 1.000 85.34181  ? 269 TYR A CE1  1 
ATOM   4152 C  CE2  . TYR A 1 269 ? 17.32900  -41.08300 30.53400 1.000 75.77751  ? 269 TYR A CE2  1 
ATOM   4153 C  CZ   . TYR A 1 269 ? 17.04100  -39.83400 30.01800 1.000 79.39373  ? 269 TYR A CZ   1 
ATOM   4154 O  OH   . TYR A 1 269 ? 16.36400  -38.90800 30.76500 1.000 82.63886  ? 269 TYR A OH   1 
ATOM   4155 H  H    . TYR A 1 269 ? 20.32100  -43.01500 25.45300 1.000 97.37000  ? 269 TYR A H    1 
ATOM   4156 H  HA   . TYR A 1 269 ? 20.65700  -41.29000 27.51500 1.000 102.75000 ? 269 TYR A HA   1 
ATOM   4157 H  HB2  . TYR A 1 269 ? 18.68500  -42.86300 26.80900 1.000 109.92000 ? 269 TYR A HB2  1 
ATOM   4158 H  HB3  . TYR A 1 269 ? 19.22400  -43.55600 28.12900 1.000 109.92000 ? 269 TYR A HB3  1 
ATOM   4159 H  HD1  . TYR A 1 269 ? 18.39800  -40.22200 27.10500 1.000 101.28000 ? 269 TYR A HD1  1 
ATOM   4160 H  HD2  . TYR A 1 269 ? 18.20800  -42.85400 30.12100 1.000 97.65000  ? 269 TYR A HD2  1 
ATOM   4161 H  HE1  . TYR A 1 269 ? 17.25000  -38.66400 28.37900 1.000 102.52000 ? 269 TYR A HE1  1 
ATOM   4162 H  HE2  . TYR A 1 269 ? 17.05800  -41.30500 31.40900 1.000 91.05000  ? 269 TYR A HE2  1 
ATOM   4163 H  HH   . TYR A 1 269 ? 16.33900  -38.08800 30.50400 1.000 99.28000  ? 269 TYR A HH   1 
ATOM   4164 N  N    . GLN A 1 270 ? 22.49700  -43.80200 27.61500 1.000 81.34133  ? 270 GLN A N    1 
ATOM   4165 C  CA   . GLN A 1 270 ? 23.44500  -44.59700 28.37900 1.000 82.55727  ? 270 GLN A CA   1 
ATOM   4166 C  C    . GLN A 1 270 ? 24.89700  -44.24400 28.10100 1.000 79.38320  ? 270 GLN A C    1 
ATOM   4167 O  O    . GLN A 1 270 ? 25.77400  -44.67500 28.85800 1.000 78.96999  ? 270 GLN A O    1 
ATOM   4168 C  CB   . GLN A 1 270 ? 23.25200  -46.09700 28.09300 1.000 84.96282  ? 270 GLN A CB   1 
ATOM   4169 C  CG   . GLN A 1 270 ? 21.88600  -46.47900 27.53000 1.000 90.83721  ? 270 GLN A CG   1 
ATOM   4170 C  CD   . GLN A 1 270 ? 21.78500  -47.96000 27.19600 1.000 92.56110  ? 270 GLN A CD   1 
ATOM   4171 O  OE1  . GLN A 1 270 ? 22.39100  -48.80000 27.86200 1.000 90.41347  ? 270 GLN A OE1  1 
ATOM   4172 N  NE2  . GLN A 1 270 ? 21.01500  -48.28500 26.16200 1.000 88.27111  ? 270 GLN A NE2  1 
ATOM   4173 H  H    . GLN A 1 270 ? 22.55500  -43.92000 26.76500 1.000 97.72000  ? 270 GLN A H    1 
ATOM   4174 H  HA   . GLN A 1 270 ? 23.27100  -44.44900 29.32200 1.000 99.18000  ? 270 GLN A HA   1 
ATOM   4175 H  HB2  . GLN A 1 270 ? 23.92000  -46.37500 27.44700 1.000 102.07000 ? 270 GLN A HB2  1 
ATOM   4176 H  HB3  . GLN A 1 270 ? 23.37000  -46.58500 28.92300 1.000 102.07000 ? 270 GLN A HB3  1 
ATOM   4177 H  HG2  . GLN A 1 270 ? 21.20300  -46.27100 28.18600 1.000 109.12000 ? 270 GLN A HG2  1 
ATOM   4178 H  HG3  . GLN A 1 270 ? 21.72800  -45.97600 26.71600 1.000 109.12000 ? 270 GLN A HG3  1 
ATOM   4179 H  HE21 . GLN A 1 270 ? 20.60600  -47.67100 25.72000 1.000 106.04000 ? 270 GLN A HE21 1 
ATOM   4180 H  HE22 . GLN A 1 270 ? 20.92600  -49.11000 25.93500 1.000 106.04000 ? 270 GLN A HE22 1 
ATOM   4181 N  N    . CYS A 1 271 ? 25.17900  -43.47800 27.04800 1.000 73.17193  ? 271 CYS A N    1 
ATOM   4182 C  CA   . CYS A 1 271 ? 26.55300  -43.24200 26.62600 1.000 68.18712  ? 271 CYS A CA   1 
ATOM   4183 C  C    . CYS A 1 271 ? 26.61400  -42.11200 25.60700 1.000 68.86089  ? 271 CYS A C    1 
ATOM   4184 O  O    . CYS A 1 271 ? 25.93400  -42.16100 24.57700 1.000 72.00337  ? 271 CYS A O    1 
ATOM   4185 C  CB   . CYS A 1 271 ? 27.14300  -44.52400 26.03500 1.000 74.78528  ? 271 CYS A CB   1 
ATOM   4186 S  SG   . CYS A 1 271 ? 28.93300  -44.54000 25.92200 1.000 81.65190  ? 271 CYS A SG   1 
ATOM   4187 H  H    . CYS A 1 271 ? 24.58900  -43.08400 26.56200 1.000 87.92000  ? 271 CYS A H    1 
ATOM   4188 H  HA   . CYS A 1 271 ? 27.08700  -42.98300 27.39300 1.000 81.94000  ? 271 CYS A HA   1 
ATOM   4189 H  HB2  . CYS A 1 271 ? 26.87800  -45.27100 26.59500 1.000 89.86000  ? 271 CYS A HB2  1 
ATOM   4190 H  HB3  . CYS A 1 271 ? 26.79200  -44.64000 25.13900 1.000 89.86000  ? 271 CYS A HB3  1 
ATOM   4191 H  HG   . CYS A 1 271 ? 29.28300  -45.57100 25.41500 1.000 98.10000  ? 271 CYS A HG   1 
ATOM   4192 N  N    . GLY A 1 272 ? 27.42200  -41.09400 25.88000 1.000 66.24215  ? 272 GLY A N    1 
ATOM   4193 C  CA   . GLY A 1 272 ? 27.52800  -39.97900 24.95700 1.000 65.85526  ? 272 GLY A CA   1 
ATOM   4194 C  C    . GLY A 1 272 ? 28.59200  -39.00400 25.40600 1.000 60.69938  ? 272 GLY A C    1 
ATOM   4195 O  O    . GLY A 1 272 ? 29.29200  -39.22100 26.39800 1.000 59.22026  ? 272 GLY A O    1 
ATOM   4196 H  H    . GLY A 1 272 ? 27.91200  -41.02800 26.58400 1.000 79.60000  ? 272 GLY A H    1 
ATOM   4197 H  HA2  . GLY A 1 272 ? 27.75900  -40.30700 24.07400 1.000 79.14000  ? 272 GLY A HA2  1 
ATOM   4198 H  HA3  . GLY A 1 272 ? 26.67900  -39.51300 24.91000 1.000 79.14000  ? 272 GLY A HA3  1 
ATOM   4199 N  N    . HIS A 1 273 ? 28.69800  -37.91100 24.65100 1.000 58.36226  ? 273 HIS A N    1 
ATOM   4200 C  CA   . HIS A 1 273 ? 29.70800  -36.89000 24.88300 1.000 53.52484  ? 273 HIS A CA   1 
ATOM   4201 C  C    . HIS A 1 273 ? 29.09700  -35.51800 24.64800 1.000 53.63801  ? 273 HIS A C    1 
ATOM   4202 O  O    . HIS A 1 273 ? 28.28600  -35.34000 23.73400 1.000 55.05397  ? 273 HIS A O    1 
ATOM   4203 C  CB   . HIS A 1 273 ? 30.91800  -37.08700 23.96500 1.000 59.62294  ? 273 HIS A CB   1 
ATOM   4204 C  CG   . HIS A 1 273 ? 32.06400  -36.17400 24.27000 1.000 61.61002  ? 273 HIS A CG   1 
ATOM   4205 N  ND1  . HIS A 1 273 ? 32.98000  -36.43600 25.26700 1.000 54.78288  ? 273 HIS A ND1  1 
ATOM   4206 C  CD2  . HIS A 1 273 ? 32.44400  -35.00200 23.70800 1.000 57.63059  ? 273 HIS A CD2  1 
ATOM   4207 C  CE1  . HIS A 1 273 ? 33.87400  -35.46400 25.30400 1.000 59.97298  ? 273 HIS A CE1  1 
ATOM   4208 N  NE2  . HIS A 1 273 ? 33.57200  -34.58200 24.36900 1.000 56.90419  ? 273 HIS A NE2  1 
ATOM   4209 H  H    . HIS A 1 273 ? 28.18300  -37.73800 23.98500 1.000 70.15000  ? 273 HIS A H    1 
ATOM   4210 H  HA   . HIS A 1 273 ? 30.01100  -36.93300 25.80300 1.000 64.34000  ? 273 HIS A HA   1 
ATOM   4211 H  HB2  . HIS A 1 273 ? 31.23400  -38.00000 24.05800 1.000 71.66000  ? 273 HIS A HB2  1 
ATOM   4212 H  HB3  . HIS A 1 273 ? 30.64500  -36.92300 23.04900 1.000 71.66000  ? 273 HIS A HB3  1 
ATOM   4213 H  HD2  . HIS A 1 273 ? 32.02000  -34.56400 23.00500 1.000 69.27000  ? 273 HIS A HD2  1 
ATOM   4214 H  HE1  . HIS A 1 273 ? 34.59500  -35.41100 25.89000 1.000 72.08000  ? 273 HIS A HE1  1 
ATOM   4215 H  HE2  . HIS A 1 273 ? 34.01000  -33.86100 24.20200 1.000 68.40000  ? 273 HIS A HE2  1 
ATOM   4216 N  N    . TYR A 1 274 ? 29.49000  -34.55400 25.47400 1.000 51.96676  ? 274 TYR A N    1 
ATOM   4217 C  CA   . TYR A 1 274 ? 28.98800  -33.19200 25.38400 1.000 48.68478  ? 274 TYR A CA   1 
ATOM   4218 C  C    . TYR A 1 274 ? 30.03000  -32.28300 24.74400 1.000 50.13233  ? 274 TYR A C    1 
ATOM   4219 O  O    . TYR A 1 274 ? 31.23800  -32.50200 24.86900 1.000 47.56623  ? 274 TYR A O    1 
ATOM   4220 C  CB   . TYR A 1 274 ? 28.62100  -32.64200 26.76500 1.000 50.66923  ? 274 TYR A CB   1 
ATOM   4221 C  CG   . TYR A 1 274 ? 27.20400  -32.93200 27.21600 1.000 47.72677  ? 274 TYR A CG   1 
ATOM   4222 C  CD1  . TYR A 1 274 ? 26.12900  -32.20400 26.72300 1.000 46.27134  ? 274 TYR A CD1  1 
ATOM   4223 C  CD2  . TYR A 1 274 ? 26.94500  -33.92500 28.15000 1.000 46.80298  ? 274 TYR A CD2  1 
ATOM   4224 C  CE1  . TYR A 1 274 ? 24.83500  -32.46500 27.14200 1.000 50.70345  ? 274 TYR A CE1  1 
ATOM   4225 C  CE2  . TYR A 1 274 ? 25.65900  -34.19500 28.57300 1.000 47.01616  ? 274 TYR A CE2  1 
ATOM   4226 C  CZ   . TYR A 1 274 ? 24.60700  -33.46300 28.06900 1.000 50.68766  ? 274 TYR A CZ   1 
ATOM   4227 O  OH   . TYR A 1 274 ? 23.32600  -33.73300 28.49600 1.000 49.79281  ? 274 TYR A OH   1 
ATOM   4228 H  H    . TYR A 1 274 ? 30.05900  -34.66900 26.10900 1.000 62.47000  ? 274 TYR A H    1 
ATOM   4229 H  HA   . TYR A 1 274 ? 28.19000  -33.19000 24.83200 1.000 58.53000  ? 274 TYR A HA   1 
ATOM   4230 H  HB2  . TYR A 1 274 ? 29.22000  -33.03300 27.42000 1.000 60.91000  ? 274 TYR A HB2  1 
ATOM   4231 H  HB3  . TYR A 1 274 ? 28.73000  -31.67800 26.75100 1.000 60.91000  ? 274 TYR A HB3  1 
ATOM   4232 H  HD1  . TYR A 1 274 ? 26.28100  -31.53000 26.10000 1.000 55.64000  ? 274 TYR A HD1  1 
ATOM   4233 H  HD2  . TYR A 1 274 ? 27.65200  -34.42000 28.49800 1.000 56.28000  ? 274 TYR A HD2  1 
ATOM   4234 H  HE1  . TYR A 1 274 ? 24.12400  -31.97200 26.80200 1.000 60.96000  ? 274 TYR A HE1  1 
ATOM   4235 H  HE2  . TYR A 1 274 ? 25.50300  -34.86700 29.19700 1.000 56.54000  ? 274 TYR A HE2  1 
ATOM   4236 H  HH   . TYR A 1 274 ? 22.78500  -33.20100 28.13700 1.000 59.86000  ? 274 TYR A HH   1 
ATOM   4237 N  N    . LYS A 1 275 ? 29.54300  -31.25500 24.05600 1.000 44.29215  ? 275 LYS A N    1 
ATOM   4238 C  CA   . LYS A 1 275 ? 30.38000  -30.20000 23.51000 1.000 47.21356  ? 275 LYS A CA   1 
ATOM   4239 C  C    . LYS A 1 275 ? 29.73000  -28.85900 23.81500 1.000 42.67091  ? 275 LYS A C    1 
ATOM   4240 O  O    . LYS A 1 275 ? 28.50800  -28.76000 23.94500 1.000 42.17611  ? 275 LYS A O    1 
ATOM   4241 C  CB   . LYS A 1 275 ? 30.58200  -30.36500 21.99400 1.000 45.13699  ? 275 LYS A CB   1 
ATOM   4242 C  CG   . LYS A 1 275 ? 31.77500  -31.23400 21.62300 1.000 46.37398  ? 275 LYS A CG   1 
ATOM   4243 C  CD   . LYS A 1 275 ? 32.03000  -31.23200 20.12200 1.000 50.66660  ? 275 LYS A CD   1 
ATOM   4244 C  CE   . LYS A 1 275 ? 32.40600  -32.61900 19.62400 1.000 54.36968  ? 275 LYS A CE   1 
ATOM   4245 N  NZ   . LYS A 1 275 ? 32.77000  -32.61900 18.18200 1.000 62.35484  ? 275 LYS A NZ   1 
ATOM   4246 H  H    . LYS A 1 275 ? 28.70600  -31.14600 23.89000 1.000 53.27000  ? 275 LYS A H    1 
ATOM   4247 H  HA   . LYS A 1 275 ? 31.25700  -30.21900 23.92300 1.000 56.77000  ? 275 LYS A HA   1 
ATOM   4248 H  HB2  . LYS A 1 275 ? 29.78800  -30.77500 21.61700 1.000 53.60000  ? 275 LYS A HB2  1 
ATOM   4249 H  HB3  . LYS A 1 275 ? 30.72000  -29.48900 21.60200 1.000 53.60000  ? 275 LYS A HB3  1 
ATOM   4250 H  HG2  . LYS A 1 275 ? 32.56800  -30.89400 22.06600 1.000 55.42000  ? 275 LYS A HG2  1 
ATOM   4251 H  HG3  . LYS A 1 275 ? 31.60500  -32.14700 21.90100 1.000 55.42000  ? 275 LYS A HG3  1 
ATOM   4252 H  HD2  . LYS A 1 275 ? 31.22600  -30.94900 19.65800 1.000 60.91000  ? 275 LYS A HD2  1 
ATOM   4253 H  HD3  . LYS A 1 275 ? 32.76000  -30.62700 19.91900 1.000 60.91000  ? 275 LYS A HD3  1 
ATOM   4254 H  HE2  . LYS A 1 275 ? 33.16900  -32.94200 20.12900 1.000 65.36000  ? 275 LYS A HE2  1 
ATOM   4255 H  HE3  . LYS A 1 275 ? 31.65100  -33.21600 19.74500 1.000 65.36000  ? 275 LYS A HE3  1 
ATOM   4256 H  HZ1  . LYS A 1 275 ? 32.97600  -33.44400 17.92000 1.000 74.94000  ? 275 LYS A HZ1  1 
ATOM   4257 H  HZ2  . LYS A 1 275 ? 32.08600  -32.32300 17.69500 1.000 74.94000  ? 275 LYS A HZ2  1 
ATOM   4258 H  HZ3  . LYS A 1 275 ? 33.47200  -32.08900 18.04600 1.000 74.94000  ? 275 LYS A HZ3  1 
ATOM   4259 N  N    . HIS A 1 276 ? 30.55900  -27.82800 23.93100 1.000 46.03447  ? 276 HIS A N    1 
ATOM   4260 C  CA   . HIS A 1 276 ? 30.10700  -26.48000 24.24400 1.000 46.66086  ? 276 HIS A CA   1 
ATOM   4261 C  C    . HIS A 1 276 ? 30.29900  -25.57500 23.03400 1.000 45.91077  ? 276 HIS A C    1 
ATOM   4262 O  O    . HIS A 1 276 ? 31.32600  -25.64500 22.35200 1.000 50.20865  ? 276 HIS A O    1 
ATOM   4263 C  CB   . HIS A 1 276 ? 30.87300  -25.92400 25.44700 1.000 43.11833  ? 276 HIS A CB   1 
ATOM   4264 C  CG   . HIS A 1 276 ? 30.42800  -24.56200 25.87000 1.000 45.49230  ? 276 HIS A CG   1 
ATOM   4265 N  ND1  . HIS A 1 276 ? 29.45600  -24.36000 26.82600 1.000 49.50857  ? 276 HIS A ND1  1 
ATOM   4266 C  CD2  . HIS A 1 276 ? 30.82400  -23.33100 25.46900 1.000 46.87141  ? 276 HIS A CD2  1 
ATOM   4267 C  CE1  . HIS A 1 276 ? 29.27100  -23.06300 26.99400 1.000 46.73718  ? 276 HIS A CE1  1 
ATOM   4268 N  NE2  . HIS A 1 276 ? 30.08800  -22.41800 26.18200 1.000 47.80836  ? 276 HIS A NE2  1 
ATOM   4269 H  H    . HIS A 1 276 ? 31.41100  -27.88700 23.83100 1.000 55.35000  ? 276 HIS A H    1 
ATOM   4270 H  HA   . HIS A 1 276 ? 29.16200  -26.49000 24.46100 1.000 56.11000  ? 276 HIS A HA   1 
ATOM   4271 H  HB2  . HIS A 1 276 ? 30.74800  -26.52300 26.19900 1.000 51.85000  ? 276 HIS A HB2  1 
ATOM   4272 H  HB3  . HIS A 1 276 ? 31.81400  -25.87000 25.21800 1.000 51.85000  ? 276 HIS A HB3  1 
ATOM   4273 H  HD1  . HIS A 1 276 ? 29.03500  -24.98100 27.24600 1.000 59.52000  ? 276 HIS A HD1  1 
ATOM   4274 H  HD2  . HIS A 1 276 ? 31.47300  -23.14100 24.83100 1.000 56.36000  ? 276 HIS A HD2  1 
ATOM   4275 H  HE1  . HIS A 1 276 ? 28.66900  -22.67100 27.58500 1.000 56.20000  ? 276 HIS A HE1  1 
ATOM   4276 N  N    . ILE A 1 277 ? 29.30500  -24.72800 22.77000 1.000 45.23963  ? 277 ILE A N    1 
ATOM   4277 C  CA   . ILE A 1 277 ? 29.32800  -23.78500 21.65500 1.000 49.54278  ? 277 ILE A CA   1 
ATOM   4278 C  C    . ILE A 1 277 ? 28.99800  -22.40500 22.20900 1.000 51.47459  ? 277 ILE A C    1 
ATOM   4279 O  O    . ILE A 1 277 ? 27.92300  -22.20800 22.79000 1.000 47.08986  ? 277 ILE A O    1 
ATOM   4280 C  CB   . ILE A 1 277 ? 28.33400  -24.17600 20.54800 1.000 49.04535  ? 277 ILE A CB   1 
ATOM   4281 C  CG1  . ILE A 1 277 ? 28.82000  -25.42600 19.81100 1.000 56.69890  ? 277 ILE A CG1  1 
ATOM   4282 C  CG2  . ILE A 1 277 ? 28.14800  -23.03700 19.54600 1.000 53.02215  ? 277 ILE A CG2  1 
ATOM   4283 C  CD1  . ILE A 1 277 ? 27.95200  -26.63800 20.04000 1.000 60.63885  ? 277 ILE A CD1  1 
ATOM   4284 H  H    . ILE A 1 277 ? 28.58500  -24.68100 23.23800 1.000 54.40000  ? 277 ILE A H    1 
ATOM   4285 H  HA   . ILE A 1 277 ? 30.21800  -23.75800 21.27000 1.000 59.57000  ? 277 ILE A HA   1 
ATOM   4286 H  HB   . ILE A 1 277 ? 27.48200  -24.36200 20.97400 1.000 58.97000  ? 277 ILE A HB   1 
ATOM   4287 H  HG12 . ILE A 1 277 ? 28.82900  -25.24300 18.85900 1.000 68.15000  ? 277 ILE A HG12 1 
ATOM   4288 H  HG13 . ILE A 1 277 ? 29.71500  -25.64000 20.11700 1.000 68.15000  ? 277 ILE A HG13 1 
ATOM   4289 H  HG21 . ILE A 1 277 ? 27.53200  -23.32400 18.85300 1.000 63.74000  ? 277 ILE A HG21 1 
ATOM   4290 H  HG22 . ILE A 1 277 ? 27.78700  -22.26500 20.00900 1.000 63.74000  ? 277 ILE A HG22 1 
ATOM   4291 H  HG23 . ILE A 1 277 ? 29.00700  -22.81700 19.15500 1.000 63.74000  ? 277 ILE A HG23 1 
ATOM   4292 H  HD11 . ILE A 1 277 ? 28.31600  -27.38500 19.54200 1.000 72.88000  ? 277 ILE A HD11 1 
ATOM   4293 H  HD12 . ILE A 1 277 ? 27.94300  -26.84500 20.98800 1.000 72.88000  ? 277 ILE A HD12 1 
ATOM   4294 H  HD13 . ILE A 1 277 ? 27.05200  -26.44400 19.73600 1.000 72.88000  ? 277 ILE A HD13 1 
ATOM   4295 N  N    . THR A 1 278 ? 29.91100  -21.45300 22.02500 1.000 50.75082  ? 278 THR A N    1 
ATOM   4296 C  CA   . THR A 1 278 ? 29.75200  -20.09600 22.52800 1.000 51.34300  ? 278 THR A CA   1 
ATOM   4297 C  C    . THR A 1 278 ? 29.80300  -19.11100 21.36700 1.000 48.41896  ? 278 THR A C    1 
ATOM   4298 O  O    . THR A 1 278 ? 30.58800  -19.28400 20.42900 1.000 51.87464  ? 278 THR A O    1 
ATOM   4299 C  CB   . THR A 1 278 ? 30.83700  -19.75300 23.56200 1.000 50.04547  ? 278 THR A CB   1 
ATOM   4300 O  OG1  . THR A 1 278 ? 30.66900  -18.40100 24.00700 1.000 52.62736  ? 278 THR A OG1  1 
ATOM   4301 C  CG2  . THR A 1 278 ? 32.23200  -19.92200 22.97100 1.000 46.60296  ? 278 THR A CG2  1 
ATOM   4302 H  H    . THR A 1 278 ? 30.64800  -21.57600 21.60000 1.000 61.01000  ? 278 THR A H    1 
ATOM   4303 H  HA   . THR A 1 278 ? 28.88800  -20.00800 22.96000 1.000 61.72000  ? 278 THR A HA   1 
ATOM   4304 H  HB   . THR A 1 278 ? 30.75700  -20.35600 24.31800 1.000 60.17000  ? 278 THR A HB   1 
ATOM   4305 H  HG1  . THR A 1 278 ? 29.91800  -18.31000 24.37300 1.000 63.27000  ? 278 THR A HG1  1 
ATOM   4306 H  HG21 . THR A 1 278 ? 32.90300  -19.77500 23.65600 1.000 56.04000  ? 278 THR A HG21 1 
ATOM   4307 H  HG22 . THR A 1 278 ? 32.33600  -20.81900 22.61700 1.000 56.04000  ? 278 THR A HG22 1 
ATOM   4308 H  HG23 . THR A 1 278 ? 32.36800  -19.28300 22.25400 1.000 56.04000  ? 278 THR A HG23 1 
ATOM   4309 N  N    . SER A 1 279 ? 28.96800  -18.07500 21.44100 1.000 49.30328  ? 279 SER A N    1 
ATOM   4310 C  CA   . SER A 1 279 ? 28.79700  -17.10200 20.36300 1.000 56.92525  ? 279 SER A CA   1 
ATOM   4311 C  C    . SER A 1 279 ? 29.46400  -15.78800 20.76200 1.000 58.03591  ? 279 SER A C    1 
ATOM   4312 O  O    . SER A 1 279 ? 28.89800  -14.99800 21.52000 1.000 56.93841  ? 279 SER A O    1 
ATOM   4313 C  CB   . SER A 1 279 ? 27.31300  -16.89700 20.06200 1.000 53.96963  ? 279 SER A CB   1 
ATOM   4314 O  OG   . SER A 1 279 ? 27.12300  -15.98000 18.99800 1.000 57.98590  ? 279 SER A OG   1 
ATOM   4315 H  H    . SER A 1 279 ? 28.47500  -17.91000 22.12600 1.000 59.28000  ? 279 SER A H    1 
ATOM   4316 H  HA   . SER A 1 279 ? 29.24500  -17.43200 19.56900 1.000 68.42000  ? 279 SER A HA   1 
ATOM   4317 H  HB2  . SER A 1 279 ? 26.92300  -17.75000 19.81500 1.000 64.88000  ? 279 SER A HB2  1 
ATOM   4318 H  HB3  . SER A 1 279 ? 26.87700  -16.55000 20.85600 1.000 64.88000  ? 279 SER A HB3  1 
ATOM   4319 H  HG   . SER A 1 279 ? 27.44700  -15.23300 19.20100 1.000 69.70000  ? 279 SER A HG   1 
ATOM   4320 N  N    . LYS A 1 280 ? 30.66900  -15.55800 20.23900 1.000 62.13377  ? 280 LYS A N    1 
ATOM   4321 C  CA   . LYS A 1 280 ? 31.41900  -14.32800 20.47700 1.000 65.83158  ? 280 LYS A CA   1 
ATOM   4322 C  C    . LYS A 1 280 ? 31.57300  -13.59800 19.13900 1.000 66.85802  ? 280 LYS A C    1 
ATOM   4323 O  O    . LYS A 1 280 ? 30.58500  -13.47200 18.41300 1.000 68.14501  ? 280 LYS A O    1 
ATOM   4324 C  CB   . LYS A 1 280 ? 32.75600  -14.65600 21.14600 1.000 66.57640  ? 280 LYS A CB   1 
ATOM   4325 C  CG   . LYS A 1 280 ? 32.67500  -15.58900 22.34100 1.000 62.21272  ? 280 LYS A CG   1 
ATOM   4326 C  CD   . LYS A 1 280 ? 31.86800  -14.98800 23.47200 1.000 70.18736  ? 280 LYS A CD   1 
ATOM   4327 C  CE   . LYS A 1 280 ? 32.55400  -13.77000 24.07300 1.000 85.58658  ? 280 LYS A CE   1 
ATOM   4328 N  NZ   . LYS A 1 280 ? 31.90000  -13.34700 25.34000 1.000 89.02910  ? 280 LYS A NZ   1 
ATOM   4329 H  H    . LYS A 1 280 ? 31.08300  -16.11300 19.73000 1.000 74.67000  ? 280 LYS A H    1 
ATOM   4330 H  HA   . LYS A 1 280 ? 30.96200  -13.72900 21.08900 1.000 79.11000  ? 280 LYS A HA   1 
ATOM   4331 H  HB2  . LYS A 1 280 ? 33.33100  -15.07800 20.48900 1.000 80.01000  ? 280 LYS A HB2  1 
ATOM   4332 H  HB3  . LYS A 1 280 ? 33.15500  -13.82800 21.45400 1.000 80.01000  ? 280 LYS A HB3  1 
ATOM   4333 H  HG2  . LYS A 1 280 ? 32.24900  -16.41800 22.07100 1.000 74.77000  ? 280 LYS A HG2  1 
ATOM   4334 H  HG3  . LYS A 1 280 ? 33.57000  -15.76800 22.66800 1.000 74.77000  ? 280 LYS A HG3  1 
ATOM   4335 H  HD2  . LYS A 1 280 ? 31.00100  -14.71200 23.13500 1.000 84.34000  ? 280 LYS A HD2  1 
ATOM   4336 H  HD3  . LYS A 1 280 ? 31.75600  -15.65000 24.17200 1.000 84.34000  ? 280 LYS A HD3  1 
ATOM   4337 H  HE2  . LYS A 1 280 ? 33.48100  -13.98500 24.26500 1.000 102.82000 ? 280 LYS A HE2  1 
ATOM   4338 H  HE3  . LYS A 1 280 ? 32.50800  -13.03200 23.44500 1.000 102.82000 ? 280 LYS A HE3  1 
ATOM   4339 H  HZ1  . LYS A 1 280 ? 32.32400  -12.64300 25.68200 1.000 106.95000 ? 280 LYS A HZ1  1 
ATOM   4340 H  HZ2  . LYS A 1 280 ? 31.05200  -13.12700 25.18600 1.000 106.95000 ? 280 LYS A HZ2  1 
ATOM   4341 H  HZ3  . LYS A 1 280 ? 31.92300  -14.01300 25.93100 1.000 106.95000 ? 280 LYS A HZ3  1 
ATOM   4342 N  N    . GLU A 1 281 ? 32.77400  -13.10600 18.79800 1.000 68.94511  ? 281 GLU A N    1 
ATOM   4343 C  CA   . GLU A 1 281 ? 33.00800  -12.55000 17.46300 1.000 65.82368  ? 281 GLU A CA   1 
ATOM   4344 C  C    . GLU A 1 281 ? 32.65100  -13.55500 16.37400 1.000 68.47137  ? 281 GLU A C    1 
ATOM   4345 O  O    . GLU A 1 281 ? 32.32500  -13.16800 15.24500 1.000 70.95851  ? 281 GLU A O    1 
ATOM   4346 C  CB   . GLU A 1 281 ? 34.47100  -12.11300 17.34300 1.000 65.51049  ? 281 GLU A CB   1 
ATOM   4347 C  CG   . GLU A 1 281 ? 35.49700  -13.21800 17.62100 1.000 69.35832  ? 281 GLU A CG   1 
ATOM   4348 C  CD   . GLU A 1 281 ? 35.87600  -13.33800 19.09200 1.000 74.68264  ? 281 GLU A CD   1 
ATOM   4349 O  OE1  . GLU A 1 281 ? 35.01400  -13.08000 19.96000 1.000 74.86424  ? 281 GLU A OE1  1 
ATOM   4350 O  OE2  . GLU A 1 281 ? 37.03800  -13.69700 19.38000 1.000 78.03830  ? 281 GLU A OE2  1 
ATOM   4351 H  H    . GLU A 1 281 ? 33.46000  -13.08300 19.31700 1.000 82.84000  ? 281 GLU A H    1 
ATOM   4352 H  HA   . GLU A 1 281 ? 32.44800  -11.76800 17.33500 1.000 79.10000  ? 281 GLU A HA   1 
ATOM   4353 H  HB2  . GLU A 1 281 ? 34.62300  -11.79500 16.43900 1.000 78.73000  ? 281 GLU A HB2  1 
ATOM   4354 H  HB3  . GLU A 1 281 ? 34.63200  -11.39900 17.97800 1.000 78.73000  ? 281 GLU A HB3  1 
ATOM   4355 H  HG2  . GLU A 1 281 ? 35.12600  -14.06900 17.34000 1.000 83.34000  ? 281 GLU A HG2  1 
ATOM   4356 H  HG3  . GLU A 1 281 ? 36.30600  -13.02800 17.12100 1.000 83.34000  ? 281 GLU A HG3  1 
ATOM   4357 N  N    . THR A 1 282 ? 32.72000  -14.84300 16.69300 1.000 66.53956  ? 282 THR A N    1 
ATOM   4358 C  CA   . THR A 1 282 ? 32.23700  -15.91000 15.82900 1.000 65.44469  ? 282 THR A CA   1 
ATOM   4359 C  C    . THR A 1 282 ? 31.81900  -17.06400 16.73300 1.000 58.79389  ? 282 THR A C    1 
ATOM   4360 O  O    . THR A 1 282 ? 31.80600  -16.93400 17.96100 1.000 60.73097  ? 282 THR A O    1 
ATOM   4361 C  CB   . THR A 1 282 ? 33.30500  -16.31100 14.80200 1.000 64.43141  ? 282 THR A CB   1 
ATOM   4362 O  OG1  . THR A 1 282 ? 32.74700  -17.24400 13.86700 1.000 67.01593  ? 282 THR A OG1  1 
ATOM   4363 C  CG2  . THR A 1 282 ? 34.51300  -16.94300 15.48400 1.000 62.01796  ? 282 THR A CG2  1 
ATOM   4364 H  H    . THR A 1 282 ? 33.05400  -15.13300 17.43100 1.000 79.96000  ? 282 THR A H    1 
ATOM   4365 H  HA   . THR A 1 282 ? 31.46300  -15.60100 15.33400 1.000 78.65000  ? 282 THR A HA   1 
ATOM   4366 H  HB   . THR A 1 282 ? 33.60600  -15.51800 14.33200 1.000 77.43000  ? 282 THR A HB   1 
ATOM   4367 H  HG1  . THR A 1 282 ? 33.33100  -17.47500 13.30900 1.000 80.53000  ? 282 THR A HG1  1 
ATOM   4368 H  HG21 . THR A 1 282 ? 35.22700  -17.07200 14.84100 1.000 74.53000  ? 282 THR A HG21 1 
ATOM   4369 H  HG22 . THR A 1 282 ? 34.83100  -16.36500 16.19600 1.000 74.53000  ? 282 THR A HG22 1 
ATOM   4370 H  HG23 . THR A 1 282 ? 34.26900  -17.80200 15.86200 1.000 74.53000  ? 282 THR A HG23 1 
ATOM   4371 N  N    . LEU A 1 283 ? 31.46900  -18.19900 16.13400 1.000 59.32290  ? 283 LEU A N    1 
ATOM   4372 C  CA   . LEU A 1 283 ? 31.05500  -19.36900 16.90000 1.000 54.84868  ? 283 LEU A CA   1 
ATOM   4373 C  C    . LEU A 1 283 ? 32.28400  -20.19900 17.24900 1.000 54.94343  ? 283 LEU A C    1 
ATOM   4374 O  O    . LEU A 1 283 ? 33.02600  -20.62500 16.35700 1.000 57.78061  ? 283 LEU A O    1 
ATOM   4375 C  CB   . LEU A 1 283 ? 30.04500  -20.21100 16.12300 1.000 53.49326  ? 283 LEU A CB   1 
ATOM   4376 C  CG   . LEU A 1 283 ? 28.72700  -19.52400 15.76100 1.000 60.99416  ? 283 LEU A CG   1 
ATOM   4377 C  CD1  . LEU A 1 283 ? 27.80900  -20.49100 15.02800 1.000 62.16535  ? 283 LEU A CD1  1 
ATOM   4378 C  CD2  . LEU A 1 283 ? 28.04400  -18.97200 17.00300 1.000 57.44373  ? 283 LEU A CD2  1 
ATOM   4379 H  H    . LEU A 1 283 ? 31.46300  -18.31500 15.28200 1.000 71.30000  ? 283 LEU A H    1 
ATOM   4380 H  HA   . LEU A 1 283 ? 30.63100  -19.07500 17.72200 1.000 65.93000  ? 283 LEU A HA   1 
ATOM   4381 H  HB2  . LEU A 1 283 ? 30.46000  -20.48800 15.29200 1.000 64.30000  ? 283 LEU A HB2  1 
ATOM   4382 H  HB3  . LEU A 1 283 ? 29.82400  -20.98800 16.66000 1.000 64.30000  ? 283 LEU A HB3  1 
ATOM   4383 H  HG   . LEU A 1 283 ? 28.91400  -18.77800 15.17100 1.000 73.30000  ? 283 LEU A HG   1 
ATOM   4384 H  HD11 . LEU A 1 283 ? 26.99300  -20.02800 14.78500 1.000 74.71000  ? 283 LEU A HD11 1 
ATOM   4385 H  HD12 . LEU A 1 283 ? 28.25900  -20.81000 14.23000 1.000 74.71000  ? 283 LEU A HD12 1 
ATOM   4386 H  HD13 . LEU A 1 283 ? 27.60500  -21.23700 15.61300 1.000 74.71000  ? 283 LEU A HD13 1 
ATOM   4387 H  HD21 . LEU A 1 283 ? 27.14800  -18.68400 16.76800 1.000 69.05000  ? 283 LEU A HD21 1 
ATOM   4388 H  HD22 . LEU A 1 283 ? 28.00100  -19.66900 17.67600 1.000 69.05000  ? 283 LEU A HD22 1 
ATOM   4389 H  HD23 . LEU A 1 283 ? 28.55600  -18.21900 17.33700 1.000 69.05000  ? 283 LEU A HD23 1 
ATOM   4390 N  N    . TYR A 1 284 ? 32.49700  -20.42400 18.54200 1.000 53.24849  ? 284 TYR A N    1 
ATOM   4391 C  CA   . TYR A 1 284 ? 33.58900  -21.25000 19.03600 1.000 55.78827  ? 284 TYR A CA   1 
ATOM   4392 C  C    . TYR A 1 284 ? 33.01600  -22.52300 19.63800 1.000 52.71422  ? 284 TYR A C    1 
ATOM   4393 O  O    . TYR A 1 284 ? 32.03700  -22.47200 20.38900 1.000 53.32481  ? 284 TYR A O    1 
ATOM   4394 C  CB   . TYR A 1 284 ? 34.41600  -20.50400 20.08600 1.000 52.64579  ? 284 TYR A CB   1 
ATOM   4395 C  CG   . TYR A 1 284 ? 35.21600  -19.35000 19.53700 1.000 50.49290  ? 284 TYR A CG   1 
ATOM   4396 C  CD1  . TYR A 1 284 ? 36.35200  -19.57000 18.77100 1.000 57.52532  ? 284 TYR A CD1  1 
ATOM   4397 C  CD2  . TYR A 1 284 ? 34.83900  -18.03800 19.78800 1.000 56.10410  ? 284 TYR A CD2  1 
ATOM   4398 C  CE1  . TYR A 1 284 ? 37.08800  -18.51700 18.26600 1.000 54.52759  ? 284 TYR A CE1  1 
ATOM   4399 C  CE2  . TYR A 1 284 ? 35.56900  -16.97800 19.28700 1.000 61.93374  ? 284 TYR A CE2  1 
ATOM   4400 C  CZ   . TYR A 1 284 ? 36.69300  -17.22400 18.52700 1.000 56.30675  ? 284 TYR A CZ   1 
ATOM   4401 O  OH   . TYR A 1 284 ? 37.42500  -16.17400 18.02700 1.000 62.16008  ? 284 TYR A OH   1 
ATOM   4402 H  H    . TYR A 1 284 ? 32.00600  -20.09900 19.16900 1.000 64.01000  ? 284 TYR A H    1 
ATOM   4403 H  HA   . TYR A 1 284 ? 34.17500  -21.48500 18.29900 1.000 67.06000  ? 284 TYR A HA   1 
ATOM   4404 H  HB2  . TYR A 1 284 ? 33.81400  -20.15100 20.76000 1.000 63.29000  ? 284 TYR A HB2  1 
ATOM   4405 H  HB3  . TYR A 1 284 ? 35.03800  -21.12800 20.49100 1.000 63.29000  ? 284 TYR A HB3  1 
ATOM   4406 H  HD1  . TYR A 1 284 ? 36.62200  -20.44300 18.59500 1.000 69.14000  ? 284 TYR A HD1  1 
ATOM   4407 H  HD2  . TYR A 1 284 ? 34.08200  -17.87000 20.30100 1.000 67.43000  ? 284 TYR A HD2  1 
ATOM   4408 H  HE1  . TYR A 1 284 ? 37.84600  -18.68000 17.75100 1.000 65.55000  ? 284 TYR A HE1  1 
ATOM   4409 H  HE2  . TYR A 1 284 ? 35.30500  -16.10300 19.46200 1.000 74.43000  ? 284 TYR A HE2  1 
ATOM   4410 H  HH   . TYR A 1 284 ? 37.08000  -15.44500 18.26300 1.000 74.71000  ? 284 TYR A HH   1 
ATOM   4411 N  N    . CYS A 1 285 ? 33.62300  -23.65900 19.30700 1.000 52.26679  ? 285 CYS A N    1 
ATOM   4412 C  CA   . CYS A 1 285 ? 33.25600  -24.94500 19.88500 1.000 53.40640  ? 285 CYS A CA   1 
ATOM   4413 C  C    . CYS A 1 285 ? 34.36500  -25.37900 20.83300 1.000 52.01413  ? 285 CYS A C    1 
ATOM   4414 O  O    . CYS A 1 285 ? 35.49900  -25.61300 20.40000 1.000 51.13508  ? 285 CYS A O    1 
ATOM   4415 C  CB   . CYS A 1 285 ? 33.03300  -26.00000 18.80300 1.000 53.61432  ? 285 CYS A CB   1 
ATOM   4416 S  SG   . CYS A 1 285 ? 32.51600  -27.60800 19.46000 1.000 59.98088  ? 285 CYS A SG   1 
ATOM   4417 H  H    . CYS A 1 285 ? 34.26400  -23.70900 18.73700 1.000 62.84000  ? 285 CYS A H    1 
ATOM   4418 H  HA   . CYS A 1 285 ? 32.43100  -24.85100 20.38600 1.000 64.20000  ? 285 CYS A HA   1 
ATOM   4419 H  HB2  . CYS A 1 285 ? 32.34000  -25.68800 18.20000 1.000 64.45000  ? 285 CYS A HB2  1 
ATOM   4420 H  HB3  . CYS A 1 285 ? 33.86200  -26.13000 18.31700 1.000 64.45000  ? 285 CYS A HB3  1 
ATOM   4421 H  HG   . CYS A 1 285 ? 32.36500  -28.37300 18.54800 1.000 72.09000  ? 285 CYS A HG   1 
ATOM   4422 N  N    . ILE A 1 286 ? 34.03900  -25.47800 22.11700 1.000 48.52950  ? 286 ILE A N    1 
ATOM   4423 C  CA   . ILE A 1 286 ? 34.98300  -25.88800 23.14800 1.000 52.94056  ? 286 ILE A CA   1 
ATOM   4424 C  C    . ILE A 1 286 ? 34.63300  -27.31400 23.54700 1.000 46.01604  ? 286 ILE A C    1 
ATOM   4425 O  O    . ILE A 1 286 ? 33.55500  -27.57000 24.09900 1.000 49.11642  ? 286 ILE A O    1 
ATOM   4426 C  CB   . ILE A 1 286 ? 34.95300  -24.94800 24.36200 1.000 51.77463  ? 286 ILE A CB   1 
ATOM   4427 C  CG1  . ILE A 1 286 ? 35.15100  -23.49700 23.91300 1.000 53.29850  ? 286 ILE A CG1  1 
ATOM   4428 C  CG2  . ILE A 1 286 ? 36.02200  -25.35900 25.37400 1.000 48.80322  ? 286 ILE A CG2  1 
ATOM   4429 C  CD1  . ILE A 1 286 ? 35.23700  -22.50400 25.05900 1.000 52.35628  ? 286 ILE A CD1  1 
ATOM   4430 H  H    . ILE A 1 286 ? 33.25300  -25.30700 22.42300 1.000 58.35000  ? 286 ILE A H    1 
ATOM   4431 H  HA   . ILE A 1 286 ? 35.88100  -25.88200 22.78000 1.000 63.64000  ? 286 ILE A HA   1 
ATOM   4432 H  HB   . ILE A 1 286 ? 34.08600  -25.01700 24.79000 1.000 62.24000  ? 286 ILE A HB   1 
ATOM   4433 H  HG12 . ILE A 1 286 ? 35.97700  -23.43800 23.40800 1.000 64.07000  ? 286 ILE A HG12 1 
ATOM   4434 H  HG13 . ILE A 1 286 ? 34.40100  -23.23900 23.35500 1.000 64.07000  ? 286 ILE A HG13 1 
ATOM   4435 H  HG21 . ILE A 1 286 ? 35.94300  -24.79900 26.16200 1.000 58.68000  ? 286 ILE A HG21 1 
ATOM   4436 H  HG22 . ILE A 1 286 ? 35.88900  -26.28900 25.61400 1.000 58.68000  ? 286 ILE A HG22 1 
ATOM   4437 H  HG23 . ILE A 1 286 ? 36.89800  -25.24300 24.97300 1.000 58.68000  ? 286 ILE A HG23 1 
ATOM   4438 H  HD11 . ILE A 1 286 ? 35.16200  -21.60400 24.70300 1.000 62.94000  ? 286 ILE A HD11 1 
ATOM   4439 H  HD12 . ILE A 1 286 ? 34.51300  -22.67500 25.68000 1.000 62.94000  ? 286 ILE A HD12 1 
ATOM   4440 H  HD13 . ILE A 1 286 ? 36.09100  -22.61200 25.50700 1.000 62.94000  ? 286 ILE A HD13 1 
ATOM   4441 N  N    . ASP A 1 287 ? 35.54200  -28.24400 23.26800 1.000 47.80310  ? 287 ASP A N    1 
ATOM   4442 C  CA   . ASP A 1 287 ? 35.40600  -29.65100 23.63800 1.000 49.62174  ? 287 ASP A CA   1 
ATOM   4443 C  C    . ASP A 1 287 ? 36.52100  -29.95700 24.63100 1.000 45.63442  ? 287 ASP A C    1 
ATOM   4444 O  O    . ASP A 1 287 ? 37.57500  -30.48100 24.26500 1.000 46.84246  ? 287 ASP A O    1 
ATOM   4445 C  CB   . ASP A 1 287 ? 35.47500  -30.56400 22.39500 1.000 53.12742  ? 287 ASP A CB   1 
ATOM   4446 C  CG   . ASP A 1 287 ? 35.14300  -32.00900 22.71400 1.000 53.55905  ? 287 ASP A CG   1 
ATOM   4447 O  OD1  . ASP A 1 287 ? 34.71300  -32.28300 23.85400 1.000 54.20913  ? 287 ASP A OD1  1 
ATOM   4448 O  OD2  . ASP A 1 287 ? 35.31400  -32.87100 21.82700 1.000 58.80179  ? 287 ASP A OD2  1 
ATOM   4449 H  H    . ASP A 1 287 ? 36.27400  -28.07700 22.84900 1.000 57.48000  ? 287 ASP A H    1 
ATOM   4450 H  HA   . ASP A 1 287 ? 34.54600  -29.79600 24.06300 1.000 59.66000  ? 287 ASP A HA   1 
ATOM   4451 H  HB2  . ASP A 1 287 ? 34.83800  -30.24800 21.73400 1.000 63.87000  ? 287 ASP A HB2  1 
ATOM   4452 H  HB3  . ASP A 1 287 ? 36.37300  -30.53600 22.03000 1.000 63.87000  ? 287 ASP A HB3  1 
ATOM   4453 N  N    . GLY A 1 288 ? 36.28500  -29.61700 25.89500 1.000 48.23210  ? 288 GLY A N    1 
ATOM   4454 C  CA   . GLY A 1 288 ? 37.31300  -29.74200 26.90700 1.000 48.89534  ? 288 GLY A CA   1 
ATOM   4455 C  C    . GLY A 1 288 ? 38.45200  -28.77600 26.66300 1.000 49.10852  ? 288 GLY A C    1 
ATOM   4456 O  O    . GLY A 1 288 ? 38.26700  -27.55700 26.73000 1.000 48.71637  ? 288 GLY A O    1 
ATOM   4457 H  H    . GLY A 1 288 ? 35.53600  -29.31300 26.18700 1.000 57.31000  ? 288 GLY A H    1 
ATOM   4458 H  HA2  . GLY A 1 288 ? 36.93200  -29.55800 27.78000 1.000 58.11000  ? 288 GLY A HA2  1 
ATOM   4459 H  HA3  . GLY A 1 288 ? 37.66600  -30.64500 26.90100 1.000 58.11000  ? 288 GLY A HA3  1 
ATOM   4460 N  N    . ALA A 1 289 ? 39.63900  -29.30900 26.37600 1.000 49.92967  ? 289 ALA A N    1 
ATOM   4461 C  CA   . ALA A 1 289 ? 40.77800  -28.47500 26.02200 1.000 52.82212  ? 289 ALA A CA   1 
ATOM   4462 C  C    . ALA A 1 289 ? 40.80700  -28.10800 24.54500 1.000 50.47447  ? 289 ALA A C    1 
ATOM   4463 O  O    . ALA A 1 289 ? 41.65300  -27.30200 24.14200 1.000 51.24035  ? 289 ALA A O    1 
ATOM   4464 C  CB   . ALA A 1 289 ? 42.08400  -29.18400 26.39000 1.000 51.52197  ? 289 ALA A CB   1 
ATOM   4465 H  H    . ALA A 1 289 ? 39.80700  -30.15200 26.37900 1.000 59.35000  ? 289 ALA A H    1 
ATOM   4466 H  HA   . ALA A 1 289 ? 40.72800  -27.65300 26.53500 1.000 63.50000  ? 289 ALA A HA   1 
ATOM   4467 H  HB1  . ALA A 1 289 ? 42.83100  -28.61600 26.14700 1.000 61.26000  ? 289 ALA A HB1  1 
ATOM   4468 H  HB2  . ALA A 1 289 ? 42.09300  -29.35200 27.34500 1.000 61.26000  ? 289 ALA A HB2  1 
ATOM   4469 H  HB3  . ALA A 1 289 ? 42.13500  -30.02300 25.90600 1.000 61.26000  ? 289 ALA A HB3  1 
ATOM   4470 N  N    . LEU A 1 290 ? 39.91100  -28.66800 23.73500 1.000 49.88756  ? 290 LEU A N    1 
ATOM   4471 C  CA   . LEU A 1 290 ? 39.93200  -28.45900 22.29400 1.000 54.05122  ? 290 LEU A CA   1 
ATOM   4472 C  C    . LEU A 1 290 ? 39.07000  -27.26200 21.91700 1.000 52.83265  ? 290 LEU A C    1 
ATOM   4473 O  O    . LEU A 1 290 ? 38.01400  -27.02800 22.51100 1.000 53.59327  ? 290 LEU A O    1 
ATOM   4474 C  CB   . LEU A 1 290 ? 39.43500  -29.70600 21.56100 1.000 50.30077  ? 290 LEU A CB   1 
ATOM   4475 C  CG   . LEU A 1 290 ? 40.23900  -30.99000 21.77100 1.000 51.47196  ? 290 LEU A CG   1 
ATOM   4476 C  CD1  . LEU A 1 290 ? 39.54200  -32.16500 21.09800 1.000 51.42722  ? 290 LEU A CD1  1 
ATOM   4477 C  CD2  . LEU A 1 290 ? 41.65900  -30.83100 21.24700 1.000 52.05098  ? 290 LEU A CD2  1 
ATOM   4478 H  H    . LEU A 1 290 ? 39.27300  -29.17900 24.00300 1.000 59.30000  ? 290 LEU A H    1 
ATOM   4479 H  HA   . LEU A 1 290 ? 40.84300  -28.28100 22.01200 1.000 64.98000  ? 290 LEU A HA   1 
ATOM   4480 H  HB2  . LEU A 1 290 ? 38.52900  -29.88600 21.85700 1.000 59.79000  ? 290 LEU A HB2  1 
ATOM   4481 H  HB3  . LEU A 1 290 ? 39.44200  -29.51800 20.61000 1.000 59.79000  ? 290 LEU A HB3  1 
ATOM   4482 H  HG   . LEU A 1 290 ? 40.29600  -31.17600 22.72100 1.000 61.88000  ? 290 LEU A HG   1 
ATOM   4483 H  HD11 . LEU A 1 290 ? 40.06700  -32.96800 21.24200 1.000 61.15000  ? 290 LEU A HD11 1 
ATOM   4484 H  HD12 . LEU A 1 290 ? 38.65900  -32.27200 21.48500 1.000 61.15000  ? 290 LEU A HD12 1 
ATOM   4485 H  HD13 . LEU A 1 290 ? 39.46800  -31.98500 20.14700 1.000 61.15000  ? 290 LEU A HD13 1 
ATOM   4486 H  HD21 . LEU A 1 290 ? 42.11500  -31.68600 21.30500 1.000 61.89000  ? 290 LEU A HD21 1 
ATOM   4487 H  HD22 . LEU A 1 290 ? 41.62300  -30.53800 20.32300 1.000 61.89000  ? 290 LEU A HD22 1 
ATOM   4488 H  HD23 . LEU A 1 290 ? 42.12300  -30.17100 21.78600 1.000 61.89000  ? 290 LEU A HD23 1 
ATOM   4489 N  N    . LEU A 1 291 ? 39.52800  -26.51000 20.91700 1.000 50.27971  ? 291 LEU A N    1 
ATOM   4490 C  CA   . LEU A 1 291 ? 38.83800  -25.31100 20.46200 1.000 51.76936  ? 291 LEU A CA   1 
ATOM   4491 C  C    . LEU A 1 291 ? 38.83400  -25.27700 18.94100 1.000 51.44301  ? 291 LEU A C    1 
ATOM   4492 O  O    . LEU A 1 291 ? 39.88900  -25.40000 18.31100 1.000 52.12993  ? 291 LEU A O    1 
ATOM   4493 C  CB   . LEU A 1 291 ? 39.50800  -24.04800 21.01900 1.000 54.28546  ? 291 LEU A CB   1 
ATOM   4494 C  CG   . LEU A 1 291 ? 38.99800  -22.69800 20.51200 1.000 51.16929  ? 291 LEU A CG   1 
ATOM   4495 C  CD1  . LEU A 1 291 ? 37.53600  -22.50400 20.86700 1.000 50.51132  ? 291 LEU A CD1  1 
ATOM   4496 C  CD2  . LEU A 1 291 ? 39.83900  -21.56500 21.08100 1.000 53.57484  ? 291 LEU A CD2  1 
ATOM   4497 H  H    . LEU A 1 291 ? 40.25000  -26.67900 20.48100 1.000 59.77000  ? 291 LEU A H    1 
ATOM   4498 H  HA   . LEU A 1 291 ? 37.91600  -25.33300 20.76300 1.000 62.24000  ? 291 LEU A HA   1 
ATOM   4499 H  HB2  . LEU A 1 291 ? 39.39000  -24.05000 21.98200 1.000 65.26000  ? 291 LEU A HB2  1 
ATOM   4500 H  HB3  . LEU A 1 291 ? 40.45200  -24.09200 20.80100 1.000 65.26000  ? 291 LEU A HB3  1 
ATOM   4501 H  HG   . LEU A 1 291 ? 39.07500  -22.67800 19.54500 1.000 60.84000  ? 291 LEU A HG   1 
ATOM   4502 H  HD11 . LEU A 1 291 ? 37.25600  -21.62100 20.58100 1.000 60.73000  ? 291 LEU A HD11 1 
ATOM   4503 H  HD12 . LEU A 1 291 ? 37.00900  -23.18200 20.41500 1.000 60.73000  ? 291 LEU A HD12 1 
ATOM   4504 H  HD13 . LEU A 1 291 ? 37.43100  -22.59000 21.82800 1.000 60.73000  ? 291 LEU A HD13 1 
ATOM   4505 H  HD21 . LEU A 1 291 ? 39.49600  -20.72000 20.75100 1.000 64.40000  ? 291 LEU A HD21 1 
ATOM   4506 H  HD22 . LEU A 1 291 ? 39.78600  -21.58800 22.04900 1.000 64.40000  ? 291 LEU A HD22 1 
ATOM   4507 H  HD23 . LEU A 1 291 ? 40.75900  -21.68200 20.79700 1.000 64.40000  ? 291 LEU A HD23 1 
ATOM   4508 N  N    . THR A 1 292 ? 37.64600  -25.12100 18.36100 1.000 53.62222  ? 292 THR A N    1 
ATOM   4509 C  CA   . THR A 1 292 ? 37.49200  -24.91600 16.92800 1.000 53.28007  ? 292 THR A CA   1 
ATOM   4510 C  C    . THR A 1 292 ? 36.48900  -23.79100 16.71100 1.000 55.51455  ? 292 THR A C    1 
ATOM   4511 O  O    . THR A 1 292 ? 35.68600  -23.47400 17.59300 1.000 52.70106  ? 292 THR A O    1 
ATOM   4512 C  CB   . THR A 1 292 ? 37.02400  -26.18700 16.20500 1.000 55.55929  ? 292 THR A CB   1 
ATOM   4513 O  OG1  . THR A 1 292 ? 35.70200  -26.53100 16.63900 1.000 56.08304  ? 292 THR A OG1  1 
ATOM   4514 C  CG2  . THR A 1 292 ? 37.96700  -27.35000 16.48400 1.000 52.16941  ? 292 THR A CG2  1 
ATOM   4515 H  H    . THR A 1 292 ? 36.90000  -25.13000 18.78800 1.000 64.46000  ? 292 THR A H    1 
ATOM   4516 H  HA   . THR A 1 292 ? 38.34500  -24.65900 16.54500 1.000 64.05000  ? 292 THR A HA   1 
ATOM   4517 H  HB   . THR A 1 292 ? 37.01800  -26.02600 15.24900 1.000 66.79000  ? 292 THR A HB   1 
ATOM   4518 H  HG1  . THR A 1 292 ? 35.45300  -27.24100 16.26600 1.000 67.41000  ? 292 THR A HG1  1 
ATOM   4519 H  HG21 . THR A 1 292 ? 37.71100  -28.12000 15.95200 1.000 62.03000  ? 292 THR A HG21 1 
ATOM   4520 H  HG22 . THR A 1 292 ? 38.87700  -27.10000 16.26000 1.000 62.03000  ? 292 THR A HG22 1 
ATOM   4521 H  HG23 . THR A 1 292 ? 37.92900  -27.59000 17.42400 1.000 62.03000  ? 292 THR A HG23 1 
ATOM   4522 N  N    . LYS A 1 293 ? 36.54000  -23.18700 15.52600 1.000 53.81698  ? 293 LYS A N    1 
ATOM   4523 C  CA   . LYS A 1 293 ? 35.68300  -22.05800 15.20100 1.000 55.68826  ? 293 LYS A CA   1 
ATOM   4524 C  C    . LYS A 1 293 ? 35.00800  -22.27800 13.85500 1.000 63.43129  ? 293 LYS A C    1 
ATOM   4525 O  O    . LYS A 1 293 ? 35.45500  -23.07900 13.02900 1.000 61.19418  ? 293 LYS A O    1 
ATOM   4526 C  CB   . LYS A 1 293 ? 36.47100  -20.73600 15.17800 1.000 60.40461  ? 293 LYS A CB   1 
ATOM   4527 C  CG   . LYS A 1 293 ? 37.46300  -20.60600 14.02800 1.000 60.54937  ? 293 LYS A CG   1 
ATOM   4528 C  CD   . LYS A 1 293 ? 38.05700  -19.20400 13.95900 1.000 62.00480  ? 293 LYS A CD   1 
ATOM   4529 C  CE   . LYS A 1 293 ? 38.49400  -18.85400 12.54400 1.000 71.91125  ? 293 LYS A CE   1 
ATOM   4530 N  NZ   . LYS A 1 293 ? 38.80700  -17.40600 12.39500 1.000 77.19610  ? 293 LYS A NZ   1 
ATOM   4531 H  H    . LYS A 1 293 ? 37.07000  -23.41800 14.88900 1.000 64.69000  ? 293 LYS A H    1 
ATOM   4532 H  HA   . LYS A 1 293 ? 34.98800  -21.99100 15.87400 1.000 66.94000  ? 293 LYS A HA   1 
ATOM   4533 H  HB2  . LYS A 1 293 ? 35.84000  -20.00300 15.10400 1.000 72.60000  ? 293 LYS A HB2  1 
ATOM   4534 H  HB3  . LYS A 1 293 ? 36.97100  -20.66100 16.00500 1.000 72.60000  ? 293 LYS A HB3  1 
ATOM   4535 H  HG2  . LYS A 1 293 ? 38.18700  -21.23800 14.15500 1.000 72.77000  ? 293 LYS A HG2  1 
ATOM   4536 H  HG3  . LYS A 1 293 ? 37.00900  -20.78600 13.19000 1.000 72.77000  ? 293 LYS A HG3  1 
ATOM   4537 H  HD2  . LYS A 1 293 ? 37.39000  -18.55900 14.24100 1.000 74.52000  ? 293 LYS A HD2  1 
ATOM   4538 H  HD3  . LYS A 1 293 ? 38.83200  -19.15500 14.53900 1.000 74.52000  ? 293 LYS A HD3  1 
ATOM   4539 H  HE2  . LYS A 1 293 ? 39.29200  -19.36000 12.32200 1.000 86.41000  ? 293 LYS A HE2  1 
ATOM   4540 H  HE3  . LYS A 1 293 ? 37.78000  -19.07400 11.92600 1.000 86.41000  ? 293 LYS A HE3  1 
ATOM   4541 H  HZ1  . LYS A 1 293 ? 39.06400  -17.23400 11.56000 1.000 92.75000  ? 293 LYS A HZ1  1 
ATOM   4542 H  HZ2  . LYS A 1 293 ? 38.08700  -16.91800 12.58100 1.000 92.75000  ? 293 LYS A HZ2  1 
ATOM   4543 H  HZ3  . LYS A 1 293 ? 39.46300  -17.17800 12.95200 1.000 92.75000  ? 293 LYS A HZ3  1 
ATOM   4544 N  N    . SER A 1 294 ? 33.92100  -21.54000 13.64700 1.000 60.59411  ? 294 SER A N    1 
ATOM   4545 C  CA   . SER A 1 294 ? 33.17800  -21.56300 12.39500 1.000 67.73970  ? 294 SER A CA   1 
ATOM   4546 C  C    . SER A 1 294 ? 32.17500  -20.41900 12.42700 1.000 67.81603  ? 294 SER A C    1 
ATOM   4547 O  O    . SER A 1 294 ? 31.81100  -19.92400 13.49700 1.000 63.08125  ? 294 SER A O    1 
ATOM   4548 C  CB   . SER A 1 294 ? 32.46600  -22.90200 12.18300 1.000 67.56336  ? 294 SER A CB   1 
ATOM   4549 O  OG   . SER A 1 294 ? 31.43700  -23.08600 13.13900 1.000 68.17660  ? 294 SER A OG   1 
ATOM   4550 H  H    . SER A 1 294 ? 33.58700  -21.00600 14.23100 1.000 72.83000  ? 294 SER A H    1 
ATOM   4551 H  HA   . SER A 1 294 ? 33.78400  -21.42400 11.65100 1.000 81.40000  ? 294 SER A HA   1 
ATOM   4552 H  HB2  . SER A 1 294 ? 32.07700  -22.91500 11.29500 1.000 81.19000  ? 294 SER A HB2  1 
ATOM   4553 H  HB3  . SER A 1 294 ? 33.11200  -23.62000 12.27300 1.000 81.19000  ? 294 SER A HB3  1 
ATOM   4554 H  HG   . SER A 1 294 ? 31.04300  -23.81400 13.00100 1.000 81.93000  ? 294 SER A HG   1 
ATOM   4555 N  N    . SER A 1 295 ? 31.73800  -20.00100 11.23800 1.000 66.91855  ? 295 SER A N    1 
ATOM   4556 C  CA   . SER A 1 295 ? 30.73200  -18.94900 11.15300 1.000 67.35018  ? 295 SER A CA   1 
ATOM   4557 C  C    . SER A 1 295 ? 29.32100  -19.49700 11.32500 1.000 65.00253  ? 295 SER A C    1 
ATOM   4558 O  O    . SER A 1 295 ? 28.44900  -18.79800 11.85300 1.000 63.10757  ? 295 SER A O    1 
ATOM   4559 C  CB   . SER A 1 295 ? 30.84800  -18.21600 9.81600  1.000 67.62127  ? 295 SER A CB   1 
ATOM   4560 O  OG   . SER A 1 295 ? 31.03200  -19.13000 8.75000  1.000 72.84558  ? 295 SER A OG   1 
ATOM   4561 H  H    . SER A 1 295 ? 32.00500  -20.30600 10.47900 1.000 80.41000  ? 295 SER A H    1 
ATOM   4562 H  HA   . SER A 1 295 ? 30.89300  -18.30500 11.86100 1.000 80.93000  ? 295 SER A HA   1 
ATOM   4563 H  HB2  . SER A 1 295 ? 30.03400  -17.71100 9.66100  1.000 81.26000  ? 295 SER A HB2  1 
ATOM   4564 H  HB3  . SER A 1 295 ? 31.60900  -17.61500 9.85100  1.000 81.26000  ? 295 SER A HB3  1 
ATOM   4565 H  HG   . SER A 1 295 ? 31.09400  -18.71500 8.02300  1.000 87.53000  ? 295 SER A HG   1 
ATOM   4566 N  N    . GLU A 1 296 ? 29.08000  -20.73300 10.89500 1.000 66.29742  ? 296 GLU A N    1 
ATOM   4567 C  CA   . GLU A 1 296 ? 27.78000  -21.37500 11.01600 1.000 66.88697  ? 296 GLU A CA   1 
ATOM   4568 C  C    . GLU A 1 296 ? 27.95200  -22.71800 11.71000 1.000 68.90300  ? 296 GLU A C    1 
ATOM   4569 O  O    . GLU A 1 296 ? 28.98300  -23.38000 11.56300 1.000 67.39492  ? 296 GLU A O    1 
ATOM   4570 C  CB   . GLU A 1 296 ? 27.12300  -21.56800 9.64100  1.000 71.79019  ? 296 GLU A CB   1 
ATOM   4571 C  CG   . GLU A 1 296 ? 26.71500  -20.26200 8.96600  1.000 75.51432  ? 296 GLU A CG   1 
ATOM   4572 C  CD   . GLU A 1 296 ? 26.78200  -20.32700 7.44900  1.000 88.98962  ? 296 GLU A CD   1 
ATOM   4573 O  OE1  . GLU A 1 296 ? 27.56600  -21.14000 6.91300  1.000 96.83793  ? 296 GLU A OE1  1 
ATOM   4574 O  OE2  . GLU A 1 296 ? 26.05200  -19.55700 6.79100  1.000 97.33272  ? 296 GLU A OE2  1 
ATOM   4575 H  H    . GLU A 1 296 ? 29.67100  -21.23100 10.51900 1.000 79.67000  ? 296 GLU A H    1 
ATOM   4576 H  HA   . GLU A 1 296 ? 27.18700  -20.82900 11.55600 1.000 80.38000  ? 296 GLU A HA   1 
ATOM   4577 H  HB2  . GLU A 1 296 ? 27.75100  -22.02000 9.05600  1.000 86.26000  ? 296 GLU A HB2  1 
ATOM   4578 H  HB3  . GLU A 1 296 ? 26.32400  -22.10700 9.75000  1.000 86.26000  ? 296 GLU A HB3  1 
ATOM   4579 H  HG2  . GLU A 1 296 ? 25.80100  -20.05100 9.21500  1.000 90.73000  ? 296 GLU A HG2  1 
ATOM   4580 H  HG3  . GLU A 1 296 ? 27.31100  -19.55500 9.26000  1.000 90.73000  ? 296 GLU A HG3  1 
ATOM   4581 N  N    . TYR A 1 297 ? 26.95400  -23.09300 12.50100 1.000 66.07634  ? 297 TYR A N    1 
ATOM   4582 C  CA   . TYR A 1 297 ? 26.99000  -24.35800 13.25800 1.000 68.69508  ? 297 TYR A CA   1 
ATOM   4583 C  C    . TYR A 1 297 ? 25.66700  -25.08400 13.11000 1.000 68.40031  ? 297 TYR A C    1 
ATOM   4584 O  O    . TYR A 1 297 ? 24.65300  -24.41200 13.02500 1.000 69.01091  ? 297 TYR A O    1 
ATOM   4585 C  CB   . TYR A 1 297 ? 27.27000  -24.10900 14.73800 1.000 65.33678  ? 297 TYR A CB   1 
ATOM   4586 C  CG   . TYR A 1 297 ? 27.82400  -25.30700 15.46100 1.000 68.94511  ? 297 TYR A CG   1 
ATOM   4587 C  CD1  . TYR A 1 297 ? 26.98900  -26.23900 16.05000 1.000 66.85802  ? 297 TYR A CD1  1 
ATOM   4588 C  CD2  . TYR A 1 297 ? 29.18800  -25.51500 15.53600 1.000 66.92118  ? 297 TYR A CD2  1 
ATOM   4589 C  CE1  . TYR A 1 297 ? 27.49700  -27.34600 16.70500 1.000 64.83146  ? 297 TYR A CE1  1 
ATOM   4590 C  CE2  . TYR A 1 297 ? 29.71400  -26.61500 16.18800 1.000 63.30233  ? 297 TYR A CE2  1 
ATOM   4591 C  CZ   . TYR A 1 297 ? 28.86600  -27.53500 16.77300 1.000 71.47173  ? 297 TYR A CZ   1 
ATOM   4592 O  OH   . TYR A 1 297 ? 29.41600  -28.61400 17.41600 1.000 73.59567  ? 297 TYR A OH   1 
ATOM   4593 H  H    . TYR A 1 297 ? 26.18800  -22.61600 12.64400 1.000 79.41000  ? 297 TYR A H    1 
ATOM   4594 H  HA   . TYR A 1 297 ? 27.70100  -24.93900 12.89700 1.000 82.55000  ? 297 TYR A HA   1 
ATOM   4595 H  HB2  . TYR A 1 297 ? 27.90900  -23.37100 14.81200 1.000 78.52000  ? 297 TYR A HB2  1 
ATOM   4596 H  HB3  . TYR A 1 297 ? 26.43600  -23.83100 15.17100 1.000 78.52000  ? 297 TYR A HB3  1 
ATOM   4597 H  HD1  . TYR A 1 297 ? 26.05400  -26.11700 16.00500 1.000 80.34000  ? 297 TYR A HD1  1 
ATOM   4598 H  HD2  . TYR A 1 297 ? 29.77200  -24.89200 15.13700 1.000 80.42000  ? 297 TYR A HD2  1 
ATOM   4599 H  HE1  . TYR A 1 297 ? 26.91300  -27.96600 17.10600 1.000 77.91000  ? 297 TYR A HE1  1 
ATOM   4600 H  HE2  . TYR A 1 297 ? 30.64700  -26.73800 16.23400 1.000 76.08000  ? 297 TYR A HE2  1 
ATOM   4601 H  HH   . TYR A 1 297 ? 29.67500  -28.53800 18.23400 1.000 88.43000  ? 297 TYR A HH   1 
ATOM   4602 N  N    . LYS A 1 298 ? 25.70700  -26.38800 12.91900 1.000 67.85814  ? 298 LYS A N    1 
ATOM   4603 C  CA   . LYS A 1 298 ? 24.53300  -27.25000 12.93100 1.000 69.34779  ? 298 LYS A CA   1 
ATOM   4604 C  C    . LYS A 1 298 ? 24.92200  -28.56700 13.58200 1.000 68.82404  ? 298 LYS A C    1 
ATOM   4605 O  O    . LYS A 1 298 ? 25.92200  -29.17800 13.19300 1.000 70.93745  ? 298 LYS A O    1 
ATOM   4606 C  CB   . LYS A 1 298 ? 24.00000  -27.49000 11.51400 1.000 75.11427  ? 298 LYS A CB   1 
ATOM   4607 C  CG   . LYS A 1 298 ? 22.62700  -28.14500 11.47100 1.000 79.60428  ? 298 LYS A CG   1 
ATOM   4608 C  CD   . LYS A 1 298 ? 22.25600  -28.58000 10.06000 1.000 90.98986  ? 298 LYS A CD   1 
ATOM   4609 C  CE   . LYS A 1 298 ? 20.96400  -29.38600 10.04800 1.000 93.33751  ? 298 LYS A CE   1 
ATOM   4610 N  NZ   . LYS A 1 298 ? 21.21500  -30.85500 10.02300 1.000 97.69066  ? 298 LYS A NZ   1 
ATOM   4611 H  H    . LYS A 1 298 ? 26.43700  -26.81000 12.75100 1.000 81.54000  ? 298 LYS A H    1 
ATOM   4612 H  HA   . LYS A 1 298 ? 23.82200  -26.84000 13.44800 1.000 83.33000  ? 298 LYS A HA   1 
ATOM   4613 H  HB2  . LYS A 1 298 ? 23.93400  -26.63600 11.05900 1.000 90.25000  ? 298 LYS A HB2  1 
ATOM   4614 H  HB3  . LYS A 1 298 ? 24.61800  -28.07100 11.04400 1.000 90.25000  ? 298 LYS A HB3  1 
ATOM   4615 H  HG2  . LYS A 1 298 ? 22.62800  -28.93000 12.04100 1.000 95.64000  ? 298 LYS A HG2  1 
ATOM   4616 H  HG3  . LYS A 1 298 ? 21.96000  -27.51200 11.77900 1.000 95.64000  ? 298 LYS A HG3  1 
ATOM   4617 H  HD2  . LYS A 1 298 ? 22.13000  -27.79500 9.50400  1.000 109.30000 ? 298 LYS A HD2  1 
ATOM   4618 H  HD3  . LYS A 1 298 ? 22.96400  -29.13400 9.69800  1.000 109.30000 ? 298 LYS A HD3  1 
ATOM   4619 H  HE2  . LYS A 1 298 ? 20.45400  -29.18100 10.84700 1.000 112.12000 ? 298 LYS A HE2  1 
ATOM   4620 H  HE3  . LYS A 1 298 ? 20.45200  -29.15400 9.25800  1.000 112.12000 ? 298 LYS A HE3  1 
ATOM   4621 H  HZ1  . LYS A 1 298 ? 20.44200  -31.29600 10.03100 1.000 117.34000 ? 298 LYS A HZ1  1 
ATOM   4622 H  HZ2  . LYS A 1 298 ? 21.66600  -31.07400 9.28800  1.000 117.34000 ? 298 LYS A HZ2  1 
ATOM   4623 H  HZ3  . LYS A 1 298 ? 21.69100  -31.09500 10.73600 1.000 117.34000 ? 298 LYS A HZ3  1 
ATOM   4624 N  N    . GLY A 1 299 ? 24.14400  -28.99700 14.57200 1.000 67.87130  ? 299 GLY A N    1 
ATOM   4625 C  CA   . GLY A 1 299 ? 24.43200  -30.22300 15.27700 1.000 62.24167  ? 299 GLY A CA   1 
ATOM   4626 C  C    . GLY A 1 299 ? 23.33800  -30.61400 16.24800 1.000 61.66002  ? 299 GLY A C    1 
ATOM   4627 O  O    . GLY A 1 299 ? 22.29100  -29.96500 16.33900 1.000 56.67785  ? 299 GLY A O    1 
ATOM   4628 H  H    . GLY A 1 299 ? 23.44100  -28.58700 14.85000 1.000 81.56000  ? 299 GLY A H    1 
ATOM   4629 H  HA2  . GLY A 1 299 ? 24.53900  -30.94200 14.63500 1.000 74.80000  ? 299 GLY A HA2  1 
ATOM   4630 H  HA3  . GLY A 1 299 ? 25.25700  -30.11800 15.77500 1.000 74.80000  ? 299 GLY A HA3  1 
ATOM   4631 N  N    . PRO A 1 300 ? 23.56300  -31.69900 16.99500 1.000 59.22026  ? 300 PRO A N    1 
ATOM   4632 C  CA   . PRO A 1 300 ? 22.57100  -32.17100 17.98600 1.000 56.59626  ? 300 PRO A CA   1 
ATOM   4633 C  C    . PRO A 1 300 ? 22.58400  -31.33200 19.26100 1.000 56.29622  ? 300 PRO A C    1 
ATOM   4634 O  O    . PRO A 1 300 ? 23.15000  -31.68700 20.29500 1.000 57.95958  ? 300 PRO A O    1 
ATOM   4635 C  CB   . PRO A 1 300 ? 23.01400  -33.61400 18.24100 1.000 54.84868  ? 300 PRO A CB   1 
ATOM   4636 C  CG   . PRO A 1 300 ? 24.49100  -33.58700 18.03400 1.000 62.07586  ? 300 PRO A CG   1 
ATOM   4637 C  CD   . PRO A 1 300 ? 24.75600  -32.56400 16.95000 1.000 57.79377  ? 300 PRO A CD   1 
ATOM   4638 H  HA   . PRO A 1 300 ? 21.67900  -32.17500 17.60500 1.000 68.03000  ? 300 PRO A HA   1 
ATOM   4639 H  HB2  . PRO A 1 300 ? 22.79200  -33.87500 19.14800 1.000 65.93000  ? 300 PRO A HB2  1 
ATOM   4640 H  HB3  . PRO A 1 300 ? 22.58300  -34.21100 17.60900 1.000 65.93000  ? 300 PRO A HB3  1 
ATOM   4641 H  HG2  . PRO A 1 300 ? 24.93000  -33.32900 18.86000 1.000 74.60000  ? 300 PRO A HG2  1 
ATOM   4642 H  HG3  . PRO A 1 300 ? 24.79600  -34.46500 17.75600 1.000 74.60000  ? 300 PRO A HG3  1 
ATOM   4643 H  HD2  . PRO A 1 300 ? 25.55800  -32.05600 17.14500 1.000 69.47000  ? 300 PRO A HD2  1 
ATOM   4644 H  HD3  . PRO A 1 300 ? 24.83800  -32.99400 16.08400 1.000 69.47000  ? 300 PRO A HD3  1 
ATOM   4645 N  N    . ILE A 1 301 ? 21.93900  -30.17600 19.18500 1.000 52.09309  ? 301 ILE A N    1 
ATOM   4646 C  CA   . ILE A 1 301 ? 21.88600  -29.25500 20.31200 1.000 55.05923  ? 301 ILE A CA   1 
ATOM   4647 C  C    . ILE A 1 301 ? 20.83300  -29.73500 21.30100 1.000 54.29598  ? 301 ILE A C    1 
ATOM   4648 O  O    . ILE A 1 301 ? 19.75700  -30.20500 20.91200 1.000 54.44863  ? 301 ILE A O    1 
ATOM   4649 C  CB   . ILE A 1 301 ? 21.58900  -27.82600 19.82700 1.000 51.70094  ? 301 ILE A CB   1 
ATOM   4650 C  CG1  . ILE A 1 301 ? 22.56600  -27.42500 18.71900 1.000 56.08304  ? 301 ILE A CG1  1 
ATOM   4651 C  CG2  . ILE A 1 301 ? 21.66200  -26.84900 20.99000 1.000 55.89091  ? 301 ILE A CG2  1 
ATOM   4652 C  CD1  . ILE A 1 301 ? 24.02500  -27.66600 19.05800 1.000 60.12826  ? 301 ILE A CD1  1 
ATOM   4653 H  H    . ILE A 1 301 ? 21.52100  -29.89800 18.48600 1.000 62.63000  ? 301 ILE A H    1 
ATOM   4654 H  HA   . ILE A 1 301 ? 22.74600  -29.25000 20.75900 1.000 66.18000  ? 301 ILE A HA   1 
ATOM   4655 H  HB   . ILE A 1 301 ? 20.69000  -27.80500 19.46200 1.000 62.15000  ? 301 ILE A HB   1 
ATOM   4656 H  HG12 . ILE A 1 301 ? 22.36000  -27.94000 17.92300 1.000 67.41000  ? 301 ILE A HG12 1 
ATOM   4657 H  HG13 . ILE A 1 301 ? 22.45800  -26.47800 18.53900 1.000 67.41000  ? 301 ILE A HG13 1 
ATOM   4658 H  HG21 . ILE A 1 301 ? 21.62300  -25.94400 20.64400 1.000 67.18000  ? 301 ILE A HG21 1 
ATOM   4659 H  HG22 . ILE A 1 301 ? 20.91200  -27.00900 21.58400 1.000 67.18000  ? 301 ILE A HG22 1 
ATOM   4660 H  HG23 . ILE A 1 301 ? 22.49600  -26.98700 21.46600 1.000 67.18000  ? 301 ILE A HG23 1 
ATOM   4661 H  HD11 . ILE A 1 301 ? 24.58000  -27.22600 18.39600 1.000 72.27000  ? 301 ILE A HD11 1 
ATOM   4662 H  HD12 . ILE A 1 301 ? 24.20900  -27.30200 19.93800 1.000 72.27000  ? 301 ILE A HD12 1 
ATOM   4663 H  HD13 . ILE A 1 301 ? 24.19700  -28.62100 19.05200 1.000 72.27000  ? 301 ILE A HD13 1 
ATOM   4664 N  N    . THR A 1 302 ? 21.14700  -29.61500 22.58900 1.000 50.80872  ? 302 THR A N    1 
ATOM   4665 C  CA   . THR A 1 302 ? 20.24300  -30.03300 23.65300 1.000 53.48273  ? 302 THR A CA   1 
ATOM   4666 C  C    . THR A 1 302 ? 19.94300  -28.93800 24.66400 1.000 49.31907  ? 302 THR A C    1 
ATOM   4667 O  O    . THR A 1 302 ? 18.95900  -29.06500 25.40400 1.000 50.07706  ? 302 THR A O    1 
ATOM   4668 C  CB   . THR A 1 302 ? 20.82100  -31.25100 24.39200 1.000 55.44612  ? 302 THR A CB   1 
ATOM   4669 O  OG1  . THR A 1 302 ? 19.82700  -31.80500 25.26400 1.000 64.76303  ? 302 THR A OG1  1 
ATOM   4670 C  CG2  . THR A 1 302 ? 22.05400  -30.86300 25.19600 1.000 50.09285  ? 302 THR A CG2  1 
ATOM   4671 H  H    . THR A 1 302 ? 21.88900  -29.28900 22.87500 1.000 61.08000  ? 302 THR A H    1 
ATOM   4672 H  HA   . THR A 1 302 ? 19.39900  -30.30600 23.26100 1.000 64.30000  ? 302 THR A HA   1 
ATOM   4673 H  HB   . THR A 1 302 ? 21.08600  -31.92200 23.74400 1.000 66.65000  ? 302 THR A HB   1 
ATOM   4674 H  HG1  . THR A 1 302 ? 19.20300  -32.13900 24.81200 1.000 77.83000  ? 302 THR A HG1  1 
ATOM   4675 H  HG21 . THR A 1 302 ? 22.69800  -31.58800 25.18600 1.000 60.23000  ? 302 THR A HG21 1 
ATOM   4676 H  HG22 . THR A 1 302 ? 22.46400  -30.07200 24.81400 1.000 60.23000  ? 302 THR A HG22 1 
ATOM   4677 H  HG23 . THR A 1 302 ? 21.80600  -30.67600 26.11500 1.000 60.23000  ? 302 THR A HG23 1 
ATOM   4678 N  N    . ASP A 1 303 ? 20.73800  -27.87000 24.71600 1.000 46.36872  ? 303 ASP A N    1 
ATOM   4679 C  CA   . ASP A 1 303 ? 20.51000  -26.76300 25.63300 1.000 50.06653  ? 303 ASP A CA   1 
ATOM   4680 C  C    . ASP A 1 303 ? 21.03800  -25.48700 24.99500 1.000 48.99535  ? 303 ASP A C    1 
ATOM   4681 O  O    . ASP A 1 303 ? 22.13700  -25.47900 24.43400 1.000 46.66349  ? 303 ASP A O    1 
ATOM   4682 C  CB   . ASP A 1 303 ? 21.20400  -26.98600 26.98200 1.000 46.47136  ? 303 ASP A CB   1 
ATOM   4683 C  CG   . ASP A 1 303 ? 20.67900  -28.20100 27.71800 1.000 51.64830  ? 303 ASP A CG   1 
ATOM   4684 O  OD1  . ASP A 1 303 ? 19.52800  -28.16300 28.20300 1.000 57.23055  ? 303 ASP A OD1  1 
ATOM   4685 O  OD2  . ASP A 1 303 ? 21.42500  -29.19500 27.82500 1.000 56.46993  ? 303 ASP A OD2  1 
ATOM   4686 H  H    . ASP A 1 303 ? 21.43000  -27.76300 24.21700 1.000 55.74000  ? 303 ASP A H    1 
ATOM   4687 H  HA   . ASP A 1 303 ? 19.55700  -26.67100 25.79100 1.000 60.19000  ? 303 ASP A HA   1 
ATOM   4688 H  HB2  . ASP A 1 303 ? 22.15300  -27.11400 26.83200 1.000 55.88000  ? 303 ASP A HB2  1 
ATOM   4689 H  HB3  . ASP A 1 303 ? 21.05800  -26.20900 27.54400 1.000 55.88000  ? 303 ASP A HB3  1 
ATOM   4690 N  N    . VAL A 1 304 ? 20.26100  -24.41200 25.09300 1.000 46.34240  ? 304 VAL A N    1 
ATOM   4691 C  CA   . VAL A 1 304 ? 20.65200  -23.11400 24.55400 1.000 48.20315  ? 304 VAL A CA   1 
ATOM   4692 C  C    . VAL A 1 304 ? 20.34200  -22.04700 25.59300 1.000 49.30328  ? 304 VAL A C    1 
ATOM   4693 O  O    . VAL A 1 304 ? 19.24200  -22.02000 26.15600 1.000 49.38224  ? 304 VAL A O    1 
ATOM   4694 C  CB   . VAL A 1 304 ? 19.93700  -22.80000 23.22500 1.000 46.75297  ? 304 VAL A CB   1 
ATOM   4695 C  CG1  . VAL A 1 304 ? 20.47200  -21.50900 22.62800 1.000 46.73718  ? 304 VAL A CG1  1 
ATOM   4696 C  CG2  . VAL A 1 304 ? 20.11100  -23.95100 22.24700 1.000 47.81363  ? 304 VAL A CG2  1 
ATOM   4697 H  H    . VAL A 1 304 ? 19.48900  -24.41000 25.47300 1.000 55.72000  ? 304 VAL A H    1 
ATOM   4698 H  HA   . VAL A 1 304 ? 21.60800  -23.11300 24.39100 1.000 57.96000  ? 304 VAL A HA   1 
ATOM   4699 H  HB   . VAL A 1 304 ? 18.98900  -22.68500 23.39600 1.000 56.22000  ? 304 VAL A HB   1 
ATOM   4700 H  HG11 . VAL A 1 304 ? 20.04900  -21.35900 21.76900 1.000 55.52000  ? 304 VAL A HG11 1 
ATOM   4701 H  HG12 . VAL A 1 304 ? 20.27000  -20.77500 23.22900 1.000 55.52000  ? 304 VAL A HG12 1 
ATOM   4702 H  HG13 . VAL A 1 304 ? 21.43200  -21.58800 22.51500 1.000 55.52000  ? 304 VAL A HG13 1 
ATOM   4703 H  HG21 . VAL A 1 304 ? 19.74200  -23.69300 21.38800 1.000 57.49000  ? 304 VAL A HG21 1 
ATOM   4704 H  HG22 . VAL A 1 304 ? 21.05700  -24.14700 22.15500 1.000 57.49000  ? 304 VAL A HG22 1 
ATOM   4705 H  HG23 . VAL A 1 304 ? 19.64400  -24.72900 22.58800 1.000 57.49000  ? 304 VAL A HG23 1 
ATOM   4706 N  N    . PHE A 1 305 ? 21.30700  -21.16600 25.84100 1.000 47.58728  ? 305 PHE A N    1 
ATOM   4707 C  CA   . PHE A 1 305 ? 21.18800  -20.10700 26.83300 1.000 47.38726  ? 305 PHE A CA   1 
ATOM   4708 C  C    . PHE A 1 305 ? 21.09600  -18.76200 26.12800 1.000 48.12682  ? 305 PHE A C    1 
ATOM   4709 O  O    . PHE A 1 305 ? 21.86800  -18.48700 25.20200 1.000 48.61636  ? 305 PHE A O    1 
ATOM   4710 C  CB   . PHE A 1 305 ? 22.37900  -20.12500 27.79200 1.000 49.89282  ? 305 PHE A CB   1 
ATOM   4711 C  CG   . PHE A 1 305 ? 22.39900  -21.31800 28.70300 1.000 51.09560  ? 305 PHE A CG   1 
ATOM   4712 C  CD1  . PHE A 1 305 ? 22.80200  -22.55700 28.23500 1.000 53.46431  ? 305 PHE A CD1  1 
ATOM   4713 C  CD2  . PHE A 1 305 ? 22.00500  -21.20200 30.02400 1.000 52.67210  ? 305 PHE A CD2  1 
ATOM   4714 C  CE1  . PHE A 1 305 ? 22.81600  -23.65700 29.06900 1.000 52.96688  ? 305 PHE A CE1  1 
ATOM   4715 C  CE2  . PHE A 1 305 ? 22.01800  -22.29800 30.86200 1.000 52.91161  ? 305 PHE A CE2  1 
ATOM   4716 C  CZ   . PHE A 1 305 ? 22.42200  -23.52700 30.38200 1.000 51.54039  ? 305 PHE A CZ   1 
ATOM   4717 H  H    . PHE A 1 305 ? 22.06400  -21.16400 25.43300 1.000 57.22000  ? 305 PHE A H    1 
ATOM   4718 H  HA   . PHE A 1 305 ? 20.37700  -20.23300 27.35000 1.000 56.98000  ? 305 PHE A HA   1 
ATOM   4719 H  HB2  . PHE A 1 305 ? 23.19800  -20.13500 27.27300 1.000 59.98000  ? 305 PHE A HB2  1 
ATOM   4720 H  HB3  . PHE A 1 305 ? 22.34700  -19.32900 28.34600 1.000 59.98000  ? 305 PHE A HB3  1 
ATOM   4721 H  HD1  . PHE A 1 305 ? 23.06700  -22.64900 27.34800 1.000 64.27000  ? 305 PHE A HD1  1 
ATOM   4722 H  HD2  . PHE A 1 305 ? 21.72900  -20.37600 30.35100 1.000 63.32000  ? 305 PHE A HD2  1 
ATOM   4723 H  HE1  . PHE A 1 305 ? 23.09000  -24.48400 28.74400 1.000 63.67000  ? 305 PHE A HE1  1 
ATOM   4724 H  HE2  . PHE A 1 305 ? 21.75400  -22.20900 31.74900 1.000 63.60000  ? 305 PHE A HE2  1 
ATOM   4725 H  HZ   . PHE A 1 305 ? 22.42900  -24.26800 30.94500 1.000 61.96000  ? 305 PHE A HZ   1 
ATOM   4726 N  N    . TYR A 1 306 ? 20.15200  -17.93300 26.56400 1.000 50.49290  ? 306 TYR A N    1 
ATOM   4727 C  CA   . TYR A 1 306 ? 19.94100  -16.61000 26.00000 1.000 50.21128  ? 306 TYR A CA   1 
ATOM   4728 C  C    . TYR A 1 306 ? 20.03700  -15.56000 27.09700 1.000 52.77475  ? 306 TYR A C    1 
ATOM   4729 O  O    . TYR A 1 306 ? 19.77200  -15.83700 28.27100 1.000 51.27983  ? 306 TYR A O    1 
ATOM   4730 C  CB   . TYR A 1 306 ? 18.57000  -16.50200 25.31500 1.000 50.14022  ? 306 TYR A CB   1 
ATOM   4731 C  CG   . TYR A 1 306 ? 18.33400  -17.51600 24.21700 1.000 52.40892  ? 306 TYR A CG   1 
ATOM   4732 C  CD1  . TYR A 1 306 ? 17.91500  -18.80600 24.51400 1.000 47.41884  ? 306 TYR A CD1  1 
ATOM   4733 C  CD2  . TYR A 1 306 ? 18.51600  -17.17700 22.88100 1.000 51.96413  ? 306 TYR A CD2  1 
ATOM   4734 C  CE1  . TYR A 1 306 ? 17.69200  -19.73400 23.51400 1.000 50.23760  ? 306 TYR A CE1  1 
ATOM   4735 C  CE2  . TYR A 1 306 ? 18.29600  -18.09800 21.87300 1.000 50.12706  ? 306 TYR A CE2  1 
ATOM   4736 C  CZ   . TYR A 1 306 ? 17.88500  -19.37400 22.19500 1.000 52.25627  ? 306 TYR A CZ   1 
ATOM   4737 O  OH   . TYR A 1 306 ? 17.66500  -20.29400 21.19500 1.000 51.03243  ? 306 TYR A OH   1 
ATOM   4738 H  H    . TYR A 1 306 ? 19.60800  -18.12300 27.20200 1.000 60.71000  ? 306 TYR A H    1 
ATOM   4739 H  HA   . TYR A 1 306 ? 20.62700  -16.43200 25.33800 1.000 60.36000  ? 306 TYR A HA   1 
ATOM   4740 H  HB2  . TYR A 1 306 ? 17.88000  -16.63000 25.98400 1.000 60.28000  ? 306 TYR A HB2  1 
ATOM   4741 H  HB3  . TYR A 1 306 ? 18.49100  -15.62000 24.92000 1.000 60.28000  ? 306 TYR A HB3  1 
ATOM   4742 H  HD1  . TYR A 1 306 ? 17.78200  -19.05100 25.40200 1.000 56.33000  ? 306 TYR A HD1  1 
ATOM   4743 H  HD2  . TYR A 1 306 ? 18.79000  -16.31600 22.66100 1.000 62.47000  ? 306 TYR A HD2  1 
ATOM   4744 H  HE1  . TYR A 1 306 ? 17.41400  -20.59500 23.72800 1.000 60.40000  ? 306 TYR A HE1  1 
ATOM   4745 H  HE2  . TYR A 1 306 ? 18.42500  -17.85800 20.98400 1.000 60.26000  ? 306 TYR A HE2  1 
ATOM   4746 H  HH   . TYR A 1 306 ? 17.43300  -21.03000 21.52700 1.000 61.35000  ? 306 TYR A HH   1 
ATOM   4747 N  N    . LYS A 1 307 ? 20.42500  -14.35000 26.70500 1.000 56.30412  ? 307 LYS A N    1 
ATOM   4748 C  CA   . LYS A 1 307 ? 20.42100  -13.22000 27.61800 1.000 58.42806  ? 307 LYS A CA   1 
ATOM   4749 C  C    . LYS A 1 307 ? 19.00300  -12.67500 27.76000 1.000 59.27816  ? 307 LYS A C    1 
ATOM   4750 O  O    . LYS A 1 307 ? 18.14800  -12.86200 26.89100 1.000 58.29646  ? 307 LYS A O    1 
ATOM   4751 C  CB   . LYS A 1 307 ? 21.36400  -12.12400 27.12100 1.000 66.80801  ? 307 LYS A CB   1 
ATOM   4752 C  CG   . LYS A 1 307 ? 22.83700  -12.39300 27.40700 1.000 74.24838  ? 307 LYS A CG   1 
ATOM   4753 C  CD   . LYS A 1 307 ? 23.74300  -11.76000 26.35300 1.000 94.82716  ? 307 LYS A CD   1 
ATOM   4754 C  CE   . LYS A 1 307 ? 24.17600  -12.76900 25.29400 1.000 104.00458 ? 307 LYS A CE   1 
ATOM   4755 N  NZ   . LYS A 1 307 ? 25.42200  -12.36200 24.58600 1.000 106.47066 ? 307 LYS A NZ   1 
ATOM   4756 H  H    . LYS A 1 307 ? 20.69500  -14.16000 25.91100 1.000 67.68000  ? 307 LYS A H    1 
ATOM   4757 H  HA   . LYS A 1 307 ? 20.73300  -13.50200 28.49200 1.000 70.23000  ? 307 LYS A HA   1 
ATOM   4758 H  HB2  . LYS A 1 307 ? 21.26100  -12.03700 26.16100 1.000 80.28000  ? 307 LYS A HB2  1 
ATOM   4759 H  HB3  . LYS A 1 307 ? 21.12700  -11.29000 27.55700 1.000 80.28000  ? 307 LYS A HB3  1 
ATOM   4760 H  HG2  . LYS A 1 307 ? 23.06900  -12.01900 28.27200 1.000 89.21000  ? 307 LYS A HG2  1 
ATOM   4761 H  HG3  . LYS A 1 307 ? 22.99300  -13.35000 27.40700 1.000 89.21000  ? 307 LYS A HG3  1 
ATOM   4762 H  HD2  . LYS A 1 307 ? 23.26500  -11.04100 25.91000 1.000 113.91000 ? 307 LYS A HD2  1 
ATOM   4763 H  HD3  . LYS A 1 307 ? 24.54000  -11.41200 26.78400 1.000 113.91000 ? 307 LYS A HD3  1 
ATOM   4764 H  HE2  . LYS A 1 307 ? 24.33900  -13.62400 25.72100 1.000 124.92000 ? 307 LYS A HE2  1 
ATOM   4765 H  HE3  . LYS A 1 307 ? 23.47000  -12.85600 24.63400 1.000 124.92000 ? 307 LYS A HE3  1 
ATOM   4766 H  HZ1  . LYS A 1 307 ? 25.63300  -12.96800 23.96900 1.000 127.88000 ? 307 LYS A HZ1  1 
ATOM   4767 H  HZ2  . LYS A 1 307 ? 25.30300  -11.57500 24.18800 1.000 127.88000 ? 307 LYS A HZ2  1 
ATOM   4768 H  HZ3  . LYS A 1 307 ? 26.09300  -12.29400 25.16600 1.000 127.88000 ? 307 LYS A HZ3  1 
ATOM   4769 N  N    . GLU A 1 308 ? 18.75600  -11.99400 28.87500 1.000 57.35688  ? 308 GLU A N    1 
ATOM   4770 C  CA   . GLU A 1 308 ? 17.41800  -11.48700 29.15000 1.000 59.27816  ? 308 GLU A CA   1 
ATOM   4771 C  C    . GLU A 1 308 ? 17.49500  -10.46300 30.27000 1.000 60.75202  ? 308 GLU A C    1 
ATOM   4772 O  O    . GLU A 1 308 ? 18.45700  -10.42900 31.04200 1.000 58.72283  ? 308 GLU A O    1 
ATOM   4773 C  CB   . GLU A 1 308 ? 16.46000  -12.62600 29.52400 1.000 59.68874  ? 308 GLU A CB   1 
ATOM   4774 C  CG   . GLU A 1 308 ? 15.00400  -12.20900 29.71100 1.000 61.26787  ? 308 GLU A CG   1 
ATOM   4775 C  CD   . GLU A 1 308 ? 14.42900  -11.50600 28.49500 1.000 64.57353  ? 308 GLU A CD   1 
ATOM   4776 O  OE1  . GLU A 1 308 ? 14.63500  -10.28000 28.36300 1.000 63.09441  ? 308 GLU A OE1  1 
ATOM   4777 O  OE2  . GLU A 1 308 ? 13.76700  -12.17700 27.67500 1.000 60.86782  ? 308 GLU A OE2  1 
ATOM   4778 H  H    . GLU A 1 308 ? 19.34000  -11.81600 29.48100 1.000 68.94000  ? 308 GLU A H    1 
ATOM   4779 H  HA   . GLU A 1 308 ? 17.07700  -11.03800 28.36100 1.000 71.25000  ? 308 GLU A HA   1 
ATOM   4780 H  HB2  . GLU A 1 308 ? 16.48300  -13.29200 28.81900 1.000 71.74000  ? 308 GLU A HB2  1 
ATOM   4781 H  HB3  . GLU A 1 308 ? 16.75900  -13.01700 30.36000 1.000 71.74000  ? 308 GLU A HB3  1 
ATOM   4782 H  HG2  . GLU A 1 308 ? 14.46800  -13.00100 29.87900 1.000 73.64000  ? 308 GLU A HG2  1 
ATOM   4783 H  HG3  . GLU A 1 308 ? 14.94400  -11.60200 30.46400 1.000 73.64000  ? 308 GLU A HG3  1 
ATOM   4784 N  N    . ASN A 1 309 ? 16.46700  -9.61700  30.33500 1.000 60.92309  ? 309 ASN A N    1 
ATOM   4785 C  CA   . ASN A 1 309 ? 16.27600  -8.70400  31.45500 1.000 64.31034  ? 309 ASN A CA   1 
ATOM   4786 C  C    . ASN A 1 309 ? 14.78900  -8.61400  31.77600 1.000 65.34731  ? 309 ASN A C    1 
ATOM   4787 O  O    . ASN A 1 309 ? 14.35800  -8.99100  32.87000 1.000 65.08938  ? 309 ASN A O    1 
ATOM   4788 C  CB   . ASN A 1 309 ? 16.85500  -7.32200  31.14400 1.000 68.37925  ? 309 ASN A CB   1 
ATOM   4789 C  CG   . ASN A 1 309 ? 16.61500  -6.89200  29.70700 1.000 79.98591  ? 309 ASN A CG   1 
ATOM   4790 O  OD1  . ASN A 1 309 ? 15.48600  -6.93200  29.21300 1.000 77.76459  ? 309 ASN A OD1  1 
ATOM   4791 N  ND2  . ASN A 1 309 ? 17.67800  -6.47300  29.03000 1.000 83.32052  ? 309 ASN A ND2  1 
ATOM   4792 H  H    . ASN A 1 309 ? 15.85800  -9.55200  29.73100 1.000 73.22000  ? 309 ASN A H    1 
ATOM   4793 H  HA   . ASN A 1 309 ? 16.74900  -9.03500  32.23500 1.000 77.29000  ? 309 ASN A HA   1 
ATOM   4794 H  HB2  . ASN A 1 309 ? 16.43900  -6.66700  31.72700 1.000 82.17000  ? 309 ASN A HB2  1 
ATOM   4795 H  HB3  . ASN A 1 309 ? 17.81300  -7.33900  31.29500 1.000 82.17000  ? 309 ASN A HB3  1 
ATOM   4796 H  HD21 . ASN A 1 309 ? 18.45000  -6.45600  29.40900 1.000 100.10000 ? 309 ASN A HD21 1 
ATOM   4797 H  HD22 . ASN A 1 309 ? 17.59400  -6.21900  28.21300 1.000 100.10000 ? 309 ASN A HD22 1 
ATOM   4798 N  N    . SER A 1 310 ? 13.99500  -8.13200  30.82100 1.000 68.50295  ? 310 SER A N    1 
ATOM   4799 C  CA   . SER A 1 310 ? 12.55100  -8.04000  30.98900 1.000 67.63969  ? 310 SER A CA   1 
ATOM   4800 C  C    . SER A 1 310 ? 11.89400  -8.11500  29.62100 1.000 66.66326  ? 310 SER A C    1 
ATOM   4801 O  O    . SER A 1 310 ? 12.30500  -7.40900  28.69500 1.000 67.84761  ? 310 SER A O    1 
ATOM   4802 C  CB   . SER A 1 310 ? 12.15900  -6.74000  31.70000 1.000 70.39265  ? 310 SER A CB   1 
ATOM   4803 O  OG   . SER A 1 310 ? 10.86100  -6.84000  32.25900 1.000 73.86149  ? 310 SER A OG   1 
ATOM   4804 H  H    A SER A 1 310 ? 14.27400  -7.85100  30.05800 0.500 82.32000  ? 310 SER A H    1 
ATOM   4805 H  H    B SER A 1 310 ? 14.27400  -7.85100  30.05800 0.500 82.32000  ? 310 SER A H    1 
ATOM   4806 H  HA   . SER A 1 310 ? 12.23700  -8.78600  31.52400 1.000 81.28000  ? 310 SER A HA   1 
ATOM   4807 H  HB2  . SER A 1 310 ? 12.79500  -6.56500  32.41000 1.000 84.59000  ? 310 SER A HB2  1 
ATOM   4808 H  HB3  . SER A 1 310 ? 12.17100  -6.01400  31.05700 1.000 84.59000  ? 310 SER A HB3  1 
ATOM   4809 H  HG   . SER A 1 310 ? 10.83000  -7.48100  32.80100 1.000 88.75000  ? 310 SER A HG   1 
ATOM   4810 N  N    . TYR A 1 311 ? 10.88000  -8.96900  29.49700 1.000 66.70537  ? 311 TYR A N    1 
ATOM   4811 C  CA   . TYR A 1 311 ? 10.15300  -9.13800  28.24800 1.000 63.08914  ? 311 TYR A CA   1 
ATOM   4812 C  C    . TYR A 1 311 ? 8.66300   -9.21100  28.53800 1.000 68.77667  ? 311 TYR A C    1 
ATOM   4813 O  O    . TYR A 1 311 ? 8.24600   -9.78200  29.55000 1.000 65.53154  ? 311 TYR A O    1 
ATOM   4814 C  CB   . TYR A 1 311 ? 10.60100  -10.40300 27.50100 1.000 62.55750  ? 311 TYR A CB   1 
ATOM   4815 C  CG   . TYR A 1 311 ? 9.62200   -10.87100 26.44400 1.000 67.25806  ? 311 TYR A CG   1 
ATOM   4816 C  CD1  . TYR A 1 311 ? 9.63500   -10.32400 25.16600 1.000 65.58418  ? 311 TYR A CD1  1 
ATOM   4817 C  CD2  . TYR A 1 311 ? 8.68400   -11.85700 26.72400 1.000 68.43452  ? 311 TYR A CD2  1 
ATOM   4818 C  CE1  . TYR A 1 311 ? 8.74300   -10.74700 24.19800 1.000 68.32661  ? 311 TYR A CE1  1 
ATOM   4819 C  CE2  . TYR A 1 311 ? 7.78800   -12.28600 25.76200 1.000 65.22624  ? 311 TYR A CE2  1 
ATOM   4820 C  CZ   . TYR A 1 311 ? 7.82100   -11.72700 24.50100 1.000 72.32446  ? 311 TYR A CZ   1 
ATOM   4821 O  OH   . TYR A 1 311 ? 6.93100   -12.15100 23.54000 1.000 72.23498  ? 311 TYR A OH   1 
ATOM   4822 H  H    . TYR A 1 311 ? 10.59100  -9.46800  30.13500 1.000 80.16000  ? 311 TYR A H    1 
ATOM   4823 H  HA   . TYR A 1 311 ? 10.31700  -8.37300  27.67400 1.000 75.82000  ? 311 TYR A HA   1 
ATOM   4824 H  HB2  . TYR A 1 311 ? 11.44600  -10.22300 27.06200 1.000 75.18000  ? 311 TYR A HB2  1 
ATOM   4825 H  HB3  . TYR A 1 311 ? 10.70800  -11.12200 28.14300 1.000 75.18000  ? 311 TYR A HB3  1 
ATOM   4826 H  HD1  . TYR A 1 311 ? 10.25600  -9.66300  24.95900 1.000 78.82000  ? 311 TYR A HD1  1 
ATOM   4827 H  HD2  . TYR A 1 311 ? 8.65900   -12.23600 27.57300 1.000 82.23000  ? 311 TYR A HD2  1 
ATOM   4828 H  HE1  . TYR A 1 311 ? 8.76300   -10.37200 23.34700 1.000 82.10000  ? 311 TYR A HE1  1 
ATOM   4829 H  HE2  . TYR A 1 311 ? 7.16600   -12.94700 25.96400 1.000 78.38000  ? 311 TYR A HE2  1 
ATOM   4830 H  HH   . TYR A 1 311 ? 6.42800   -12.74500 23.85600 1.000 86.79000  ? 311 TYR A HH   1 
ATOM   4831 N  N    . THR A 1 312 ? 7.86800   -8.62900  27.64200 1.000 69.13987  ? 312 THR A N    1 
ATOM   4832 C  CA   . THR A 1 312 ? 6.41500   -8.66600  27.74000 1.000 69.97681  ? 312 THR A CA   1 
ATOM   4833 C  C    . THR A 1 312 ? 5.84000   -8.89900  26.35200 1.000 70.73216  ? 312 THR A C    1 
ATOM   4834 O  O    . THR A 1 312 ? 6.27000   -8.26700  25.38100 1.000 72.30077  ? 312 THR A O    1 
ATOM   4835 C  CB   . THR A 1 312 ? 5.85600   -7.36900  28.33500 1.000 70.27158  ? 312 THR A CB   1 
ATOM   4836 O  OG1  . THR A 1 312 ? 6.52300   -7.08100  29.57000 1.000 72.58239  ? 312 THR A OG1  1 
ATOM   4837 C  CG2  . THR A 1 312 ? 4.36000   -7.49900  28.58800 1.000 71.05062  ? 312 THR A CG2  1 
ATOM   4838 H  H    . THR A 1 312 ? 8.15400   -8.19800  26.95600 1.000 83.08000  ? 312 THR A H    1 
ATOM   4839 H  HA   . THR A 1 312 ? 6.14600   -9.39800  28.31600 1.000 84.09000  ? 312 THR A HA   1 
ATOM   4840 H  HB   . THR A 1 312 ? 5.99900   -6.63900  27.71300 1.000 84.44000  ? 312 THR A HB   1 
ATOM   4841 H  HG1  . THR A 1 312 ? 6.20800   -6.38100  29.91100 1.000 87.21000  ? 312 THR A HG1  1 
ATOM   4842 H  HG21 . THR A 1 312 ? 4.03400   -6.71900  29.06300 1.000 85.37000  ? 312 THR A HG21 1 
ATOM   4843 H  HG22 . THR A 1 312 ? 3.88700   -7.57400  27.74400 1.000 85.37000  ? 312 THR A HG22 1 
ATOM   4844 H  HG23 . THR A 1 312 ? 4.18100   -8.29000  29.12100 1.000 85.37000  ? 312 THR A HG23 1 
ATOM   4845 N  N    . THR A 1 313 ? 4.87200   -9.80300  26.26400 1.000 74.44314  ? 313 THR A N    1 
ATOM   4846 C  CA   . THR A 1 313 ? 4.33900   -10.21900 24.97700 1.000 74.75633  ? 313 THR A CA   1 
ATOM   4847 C  C    . THR A 1 313 ? 3.40000   -9.16600  24.40300 1.000 79.30161  ? 313 THR A C    1 
ATOM   4848 O  O    . THR A 1 313 ? 2.77200   -8.39400  25.13300 1.000 79.69640  ? 313 THR A O    1 
ATOM   4849 C  CB   . THR A 1 313 ? 3.59200   -11.54900 25.10500 1.000 76.00911  ? 313 THR A CB   1 
ATOM   4850 O  OG1  . THR A 1 313 ? 2.96900   -11.87200 23.85600 1.000 83.87321  ? 313 THR A OG1  1 
ATOM   4851 C  CG2  . THR A 1 313 ? 2.51800   -11.47000 26.18700 1.000 76.00648  ? 313 THR A CG2  1 
ATOM   4852 H  H    . THR A 1 313 ? 4.50500   -10.19100 26.93900 1.000 89.45000  ? 313 THR A H    1 
ATOM   4853 H  HA   . THR A 1 313 ? 5.07700   -10.33800 24.35900 1.000 89.82000  ? 313 THR A HA   1 
ATOM   4854 H  HB   . THR A 1 313 ? 4.22200   -12.24400 25.35000 1.000 91.32000  ? 313 THR A HB   1 
ATOM   4855 H  HG1  . THR A 1 313 ? 2.58000   -12.61400 23.91200 1.000 100.76000 ? 313 THR A HG1  1 
ATOM   4856 H  HG21 . THR A 1 313 ? 2.02800   -12.30600 26.23000 1.000 91.32000  ? 313 THR A HG21 1 
ATOM   4857 H  HG22 . THR A 1 313 ? 2.92800   -11.30100 27.05000 1.000 91.32000  ? 313 THR A HG22 1 
ATOM   4858 H  HG23 . THR A 1 313 ? 1.89700   -10.75200 25.98700 1.000 91.32000  ? 313 THR A HG23 1 
ATOM   4859 N  N    . THR A 1 314 ? 3.31500   -9.14300  23.07400 1.000 86.52880  ? 314 THR A N    1 
ATOM   4860 C  CA   . THR A 1 314 ? 2.33100   -8.33500  22.36800 1.000 87.87896  ? 314 THR A CA   1 
ATOM   4861 C  C    . THR A 1 314 ? 1.07100   -9.11900  22.02200 1.000 94.75610  ? 314 THR A C    1 
ATOM   4862 O  O    . THR A 1 314 ? 0.11100   -8.52900  21.51500 1.000 94.78505  ? 314 THR A O    1 
ATOM   4863 C  CB   . THR A 1 314 ? 2.93800   -7.76400  21.08000 1.000 88.05266  ? 314 THR A CB   1 
ATOM   4864 O  OG1  . THR A 1 314 ? 3.26100   -8.83500  20.18400 1.000 93.02958  ? 314 THR A OG1  1 
ATOM   4865 C  CG2  . THR A 1 314 ? 4.19700   -6.96200  21.38700 1.000 84.30484  ? 314 THR A CG2  1 
ATOM   4866 H  H    . THR A 1 314 ? 3.82600   -9.59700  22.55200 1.000 103.95000 ? 314 THR A H    1 
ATOM   4867 H  HA   . THR A 1 314 ? 2.07900   -7.58700  22.93300 1.000 105.57000 ? 314 THR A HA   1 
ATOM   4868 H  HB   . THR A 1 314 ? 2.29600   -7.17200  20.65800 1.000 105.78000 ? 314 THR A HB   1 
ATOM   4869 H  HG1  . THR A 1 314 ? 3.60600   -8.52800  19.48300 1.000 111.75000 ? 314 THR A HG1  1 
ATOM   4870 H  HG21 . THR A 1 314 ? 4.53200   -6.54900  20.57600 1.000 101.28000 ? 314 THR A HG21 1 
ATOM   4871 H  HG22 . THR A 1 314 ? 3.99900   -6.26800  22.03500 1.000 101.28000 ? 314 THR A HG22 1 
ATOM   4872 H  HG23 . THR A 1 314 ? 4.88100   -7.54600  21.74900 1.000 101.28000 ? 314 THR A HG23 1 
ATOM   4873 N  N    . ILE A 1 315 ? 1.05500   -10.42800 22.28200 1.000 98.92502  ? 315 ILE A N    1 
ATOM   4874 C  CA   . ILE A 1 315 ? -0.11100  -11.24700 21.97600 1.000 99.69353  ? 315 ILE A CA   1 
ATOM   4875 C  C    . ILE A 1 315 ? -1.28500  -10.81600 22.84800 1.000 102.46492 ? 315 ILE A C    1 
ATOM   4876 O  O    . ILE A 1 315 ? -1.11800  -10.40400 24.00400 1.000 96.81687  ? 315 ILE A O    1 
ATOM   4877 C  CB   . ILE A 1 315 ? 0.22600   -12.73700 22.17700 1.000 98.49076  ? 315 ILE A CB   1 
ATOM   4878 C  CG1  . ILE A 1 315 ? 0.83300   -13.32400 20.89800 1.000 102.66231 ? 315 ILE A CG1  1 
ATOM   4879 C  CG2  . ILE A 1 315 ? -1.00900  -13.54600 22.57900 1.000 96.14311  ? 315 ILE A CG2  1 
ATOM   4880 C  CD1  . ILE A 1 315 ? 2.23800   -12.84100 20.60000 1.000 99.93567  ? 315 ILE A CD1  1 
ATOM   4881 H  H    . ILE A 1 315 ? 1.70700   -10.86200 22.63600 1.000 118.83000 ? 315 ILE A H    1 
ATOM   4882 H  HA   . ILE A 1 315 ? -0.36500  -11.11500 21.04900 1.000 119.74000 ? 315 ILE A HA   1 
ATOM   4883 H  HB   . ILE A 1 315 ? 0.87400   -12.79100 22.89700 1.000 118.30000 ? 315 ILE A HB   1 
ATOM   4884 H  HG12 . ILE A 1 315 ? 0.86600   -14.29000 20.98500 1.000 123.31000 ? 315 ILE A HG12 1 
ATOM   4885 H  HG13 . ILE A 1 315 ? 0.27100   -13.07800 20.14700 1.000 123.31000 ? 315 ILE A HG13 1 
ATOM   4886 H  HG21 . ILE A 1 315 ? -0.76400  -14.48200 22.64900 1.000 115.49000 ? 315 ILE A HG21 1 
ATOM   4887 H  HG22 . ILE A 1 315 ? -1.33200  -13.22300 23.43500 1.000 115.49000 ? 315 ILE A HG22 1 
ATOM   4888 H  HG23 . ILE A 1 315 ? -1.69400  -13.43200 21.90200 1.000 115.49000 ? 315 ILE A HG23 1 
ATOM   4889 H  HD11 . ILE A 1 315 ? 2.55000   -13.25900 19.78200 1.000 120.03000 ? 315 ILE A HD11 1 
ATOM   4890 H  HD12 . ILE A 1 315 ? 2.22500   -11.87600 20.49300 1.000 120.03000 ? 315 ILE A HD12 1 
ATOM   4891 H  HD13 . ILE A 1 315 ? 2.81900   -13.08400 21.33800 1.000 120.03000 ? 315 ILE A HD13 1 
ATOM   4892 N  N    . LYS A 1 316 ? -2.48800  -10.91700 22.28900 1.000 102.78074 ? 316 LYS A N    1 
ATOM   4893 C  CA   . LYS A 1 316 ? -3.70500  -10.57200 23.01600 1.000 100.25939 ? 316 LYS A CA   1 
ATOM   4894 C  C    . LYS A 1 316 ? -4.78500  -11.62500 22.78700 1.000 101.13055 ? 316 LYS A C    1 
ATOM   4895 O  O    . LYS A 1 316 ? -4.86300  -12.61600 23.51300 1.000 95.71937  ? 316 LYS A O    1 
ATOM   4896 C  CB   . LYS A 1 316 ? -4.21400  -9.19500  22.58700 1.000 97.10375  ? 316 LYS A CB   1 
ATOM   4897 H  H    . LYS A 1 316 ? -2.62600  -11.18500 21.48400 1.000 123.45000 ? 316 LYS A H    1 
ATOM   4898 H  HA   . LYS A 1 316 ? -3.51100  -10.53600 23.96500 1.000 120.43000 ? 316 LYS A HA   1 
HETATM 4899 ZN ZN   . ZN  B 2 .   ? -8.38600  -28.95300 25.86200 1.000 85.81000  ? 401 ZN  A ZN   1 
HETATM 4900 C  C1   . GOL C 3 .   ? 20.62000  -36.16900 26.38600 0.970 72.79000  ? 402 GOL A C1   1 
HETATM 4901 O  O1   . GOL C 3 .   ? 19.50500  -36.83700 25.80200 0.970 73.10000  ? 402 GOL A O1   1 
HETATM 4902 C  C2   . GOL C 3 .   ? 21.39300  -37.08900 27.30600 0.970 74.72000  ? 402 GOL A C2   1 
HETATM 4903 O  O2   . GOL C 3 .   ? 22.52200  -36.39900 27.83700 0.970 69.12000  ? 402 GOL A O2   1 
HETATM 4904 C  C3   . GOL C 3 .   ? 20.55000  -37.64100 28.43500 0.970 71.25000  ? 402 GOL A C3   1 
HETATM 4905 O  O3   . GOL C 3 .   ? 21.28800  -37.71400 29.65200 0.970 77.72000  ? 402 GOL A O3   1 
HETATM 4906 H  H11  . GOL C 3 .   ? 20.30400  -35.38800 26.90200 0.970 87.46000  ? 402 GOL A H11  1 
HETATM 4907 H  H12  . GOL C 3 .   ? 21.21800  -35.84700 25.67000 0.970 87.46000  ? 402 GOL A H12  1 
HETATM 4908 H  HO1  . GOL C 3 .   ? 18.84200  -36.31200 25.80500 0.970 87.83000  ? 402 GOL A HO1  1 
HETATM 4909 H  H2   . GOL C 3 .   ? 21.71800  -37.85000 26.77200 0.970 89.78000  ? 402 GOL A H2   1 
HETATM 4910 H  HO2  . GOL C 3 .   ? 22.72700  -35.78000 27.29600 0.970 83.06000  ? 402 GOL A HO2  1 
HETATM 4911 H  H31  . GOL C 3 .   ? 20.23400  -38.54400 28.19200 0.970 85.61000  ? 402 GOL A H31  1 
HETATM 4912 H  H32  . GOL C 3 .   ? 19.76200  -37.06100 28.56600 0.970 85.61000  ? 402 GOL A H32  1 
HETATM 4913 H  HO3  . GOL C 3 .   ? 21.66000  -36.96400 29.77700 0.970 93.38000  ? 402 GOL A HO3  1 
HETATM 4914 S  S    . SO4 D 4 .   ? 20.54500  -22.90200 49.08500 1.000 79.63000  ? 403 SO4 A S    1 
HETATM 4915 O  O1   . SO4 D 4 .   ? 21.93400  -23.24400 48.79500 1.000 62.86000  ? 403 SO4 A O1   1 
HETATM 4916 O  O2   . SO4 D 4 .   ? 19.91100  -22.38600 47.87500 1.000 73.49000  ? 403 SO4 A O2   1 
HETATM 4917 O  O3   . SO4 D 4 .   ? 19.83500  -24.09600 49.53900 1.000 80.37000  ? 403 SO4 A O3   1 
HETATM 4918 O  O4   . SO4 D 4 .   ? 20.50000  -21.88400 50.13100 1.000 73.81000  ? 403 SO4 A O4   1 
HETATM 4919 S  S    . SO4 E 4 .   ? 45.46000  -26.28300 53.06400 0.800 100.96000 ? 404 SO4 A S    1 
HETATM 4920 O  O1   . SO4 E 4 .   ? 46.63600  -26.96100 52.52400 0.800 95.96000  ? 404 SO4 A O1   1 
HETATM 4921 O  O2   . SO4 E 4 .   ? 44.39800  -26.27600 52.06100 0.800 92.45000  ? 404 SO4 A O2   1 
HETATM 4922 O  O3   . SO4 E 4 .   ? 45.00000  -26.98600 54.25800 0.800 84.52000  ? 404 SO4 A O3   1 
HETATM 4923 O  O4   . SO4 E 4 .   ? 45.80900  -24.90800 53.41300 0.800 93.73000  ? 404 SO4 A O4   1 
HETATM 4924 S  S    . SO4 F 4 .   ? 33.46100  -21.38100 8.21900  0.720 86.29000  ? 405 SO4 A S    1 
HETATM 4925 O  O1   . SO4 F 4 .   ? 34.50400  -22.24900 7.67900  0.720 79.53000  ? 405 SO4 A O1   1 
HETATM 4926 O  O2   . SO4 F 4 .   ? 32.95400  -20.51300 7.15900  0.720 78.44000  ? 405 SO4 A O2   1 
HETATM 4927 O  O3   . SO4 F 4 .   ? 32.37000  -22.19900 8.74300  0.720 70.38000  ? 405 SO4 A O3   1 
HETATM 4928 O  O4   . SO4 F 4 .   ? 34.01900  -20.56000 9.29000  0.720 74.82000  ? 405 SO4 A O4   1 
HETATM 4929 S  S    . SO4 G 4 .   ? 29.65900  -29.57600 71.08700 1.000 114.67000 ? 406 SO4 A S    1 
HETATM 4930 O  O1   . SO4 G 4 .   ? 30.54200  -29.64100 69.92600 1.000 88.52000  ? 406 SO4 A O1   1 
HETATM 4931 O  O2   . SO4 G 4 .   ? 28.90600  -28.32500 71.05400 1.000 101.84000 ? 406 SO4 A O2   1 
HETATM 4932 O  O3   . SO4 G 4 .   ? 28.73200  -30.70500 71.05700 1.000 99.24000  ? 406 SO4 A O3   1 
HETATM 4933 O  O4   . SO4 G 4 .   ? 30.45600  -29.63300 72.30900 1.000 242.33000 ? 406 SO4 A O4   1 
HETATM 4934 S  S    . SO4 H 4 .   ? 46.42200  -21.81800 31.03200 1.000 234.87000 ? 407 SO4 A S    1 
HETATM 4935 O  O1   . SO4 H 4 .   ? 47.84000  -21.96700 31.34700 1.000 175.14000 ? 407 SO4 A O1   1 
HETATM 4936 O  O2   . SO4 H 4 .   ? 46.04500  -22.79600 30.01600 1.000 117.17000 ? 407 SO4 A O2   1 
HETATM 4937 O  O3   . SO4 H 4 .   ? 45.62900  -22.03800 32.23700 1.000 120.25000 ? 407 SO4 A O3   1 
HETATM 4938 O  O4   . SO4 H 4 .   ? 46.17500  -20.47100 30.52600 1.000 129.55000 ? 407 SO4 A O4   1 
HETATM 4939 S  S    . SO4 I 4 .   ? 28.44500  -12.66000 32.86800 1.000 120.38000 ? 408 SO4 A S    1 
HETATM 4940 O  O1   . SO4 I 4 .   ? 29.43000  -12.13800 31.92500 1.000 103.38000 ? 408 SO4 A O1   1 
HETATM 4941 O  O2   . SO4 I 4 .   ? 27.14700  -12.76500 32.20700 1.000 79.37000  ? 408 SO4 A O2   1 
HETATM 4942 O  O3   . SO4 I 4 .   ? 28.86600  -13.98000 33.33000 1.000 85.46000  ? 408 SO4 A O3   1 
HETATM 4943 O  O4   . SO4 I 4 .   ? 28.33600  -11.75600 34.01000 1.000 102.39000 ? 408 SO4 A O4   1 
HETATM 4944 S  S    . SO4 J 4 .   ? 35.72200  -11.88300 25.04700 1.000 163.84000 ? 409 SO4 A S    1 
HETATM 4945 O  O1   . SO4 J 4 .   ? 36.76000  -11.73600 24.03100 1.000 165.67000 ? 409 SO4 A O1   1 
HETATM 4946 O  O2   . SO4 J 4 .   ? 34.44400  -11.42600 24.50900 1.000 145.84000 ? 409 SO4 A O2   1 
HETATM 4947 O  O3   . SO4 J 4 .   ? 35.61400  -13.28700 25.43100 1.000 140.73000 ? 409 SO4 A O3   1 
HETATM 4948 O  O4   . SO4 J 4 .   ? 36.07100  -11.08400 26.21800 1.000 214.03000 ? 409 SO4 A O4   1 
HETATM 4949 S  S    . SO4 K 4 .   ? 17.93300  -35.81400 14.14600 0.610 78.88000  ? 410 SO4 A S    1 
HETATM 4950 O  O1   . SO4 K 4 .   ? 19.04700  -36.11700 13.25300 0.610 76.24000  ? 410 SO4 A O1   1 
HETATM 4951 O  O2   . SO4 K 4 .   ? 16.70200  -35.69600 13.36900 0.610 74.31000  ? 410 SO4 A O2   1 
HETATM 4952 O  O3   . SO4 K 4 .   ? 17.79100  -36.88500 15.12800 0.610 74.07000  ? 410 SO4 A O3   1 
HETATM 4953 O  O4   . SO4 K 4 .   ? 18.19000  -34.55500 14.83700 0.610 73.42000  ? 410 SO4 A O4   1 
HETATM 4954 O  O    . HOH L 5 .   ? 25.56500  -20.09300 54.96900 1.000 54.17000  ? 501 HOH A O    1 
HETATM 4955 O  O    . HOH L 5 .   ? 29.58700  -15.48000 26.29800 1.000 54.10000  ? 502 HOH A O    1 
HETATM 4956 O  O    . HOH L 5 .   ? 42.15500  -45.13300 54.73500 1.000 66.49000  ? 503 HOH A O    1 
HETATM 4957 O  O    . HOH L 5 .   ? 33.21700  -37.48500 35.65700 1.000 53.37000  ? 504 HOH A O    1 
HETATM 4958 O  O    . HOH L 5 .   ? 28.98800  -38.22800 44.27800 1.000 50.22000  ? 505 HOH A O    1 
HETATM 4959 O  O    . HOH L 5 .   ? 22.01800  -15.19500 40.94300 1.000 52.22000  ? 506 HOH A O    1 
HETATM 4960 O  O    . HOH L 5 .   ? 8.78800   -5.86700  29.69600 1.000 67.40000  ? 507 HOH A O    1 
HETATM 4961 O  O    . HOH L 5 .   ? 37.52800  -24.57700 42.65000 1.000 48.93000  ? 508 HOH A O    1 
HETATM 4962 O  O    . HOH L 5 .   ? 18.42000  -20.36300 18.71400 1.000 53.48000  ? 509 HOH A O    1 
HETATM 4963 O  O    . HOH L 5 .   ? 42.47700  -25.13300 22.87100 1.000 51.91000  ? 510 HOH A O    1 
HETATM 4964 O  O    . HOH L 5 .   ? 42.54000  -23.69100 56.56700 1.000 57.11000  ? 511 HOH A O    1 
HETATM 4965 O  O    . HOH L 5 .   ? 37.26100  -26.91500 68.50500 1.000 48.95000  ? 512 HOH A O    1 
HETATM 4966 O  O    . HOH L 5 .   ? 28.15800  -13.99200 28.37200 1.000 53.96000  ? 513 HOH A O    1 
HETATM 4967 O  O    . HOH L 5 .   ? 21.43800  -31.82900 28.77400 1.000 46.70000  ? 514 HOH A O    1 
HETATM 4968 O  O    . HOH L 5 .   ? 36.16600  -32.19500 29.43700 1.000 48.61000  ? 515 HOH A O    1 
HETATM 4969 O  O    . HOH L 5 .   ? 25.82500  -41.77100 41.81000 1.000 53.73000  ? 516 HOH A O    1 
HETATM 4970 O  O    . HOH L 5 .   ? 33.85800  -28.61200 26.62300 1.000 46.86000  ? 517 HOH A O    1 
HETATM 4971 O  O    . HOH L 5 .   ? 31.80800  -22.61900 65.19800 1.000 56.04000  ? 518 HOH A O    1 
HETATM 4972 O  O    . HOH L 5 .   ? 41.26000  -25.65400 68.43300 1.000 51.16000  ? 519 HOH A O    1 
HETATM 4973 O  O    . HOH L 5 .   ? 8.50900   -31.18600 26.95700 1.000 58.90000  ? 520 HOH A O    1 
HETATM 4974 O  O    . HOH L 5 .   ? 23.04600  -13.41800 32.20300 1.000 53.83000  ? 521 HOH A O    1 
HETATM 4975 O  O    . HOH L 5 .   ? 13.43800  -21.01800 29.61900 1.000 50.50000  ? 522 HOH A O    1 
HETATM 4976 O  O    . HOH L 5 .   ? 37.51000  -23.07000 64.54600 1.000 51.17000  ? 523 HOH A O    1 
HETATM 4977 O  O    . HOH L 5 .   ? 30.53600  -37.93400 36.63100 1.000 52.88000  ? 524 HOH A O    1 
HETATM 4978 O  O    . HOH L 5 .   ? 35.30800  -26.72500 60.28800 1.000 49.31000  ? 525 HOH A O    1 
HETATM 4979 O  O    . HOH L 5 .   ? 41.87100  -21.27000 58.21600 1.000 51.27000  ? 526 HOH A O    1 
HETATM 4980 O  O    . HOH L 5 .   ? 28.22500  -16.76200 36.89900 1.000 54.42000  ? 527 HOH A O    1 
HETATM 4981 O  O    . HOH L 5 .   ? 34.78300  -24.23500 48.82400 1.000 47.93000  ? 528 HOH A O    1 
HETATM 4982 O  O    . HOH L 5 .   ? 31.14400  -22.83900 58.09100 1.000 48.79000  ? 529 HOH A O    1 
HETATM 4983 O  O    . HOH L 5 .   ? 15.36300  -18.10400 19.68200 1.000 57.82000  ? 530 HOH A O    1 
HETATM 4984 O  O    . HOH L 5 .   ? 31.71500  -38.75100 44.67800 1.000 51.33000  ? 531 HOH A O    1 
HETATM 4985 O  O    . HOH L 5 .   ? 15.59700  -28.63600 15.75700 1.000 61.56000  ? 532 HOH A O    1 
HETATM 4986 O  O    . HOH L 5 .   ? 14.15000  -27.80100 32.01300 1.000 53.28000  ? 533 HOH A O    1 
HETATM 4987 O  O    . HOH L 5 .   ? 35.78500  -17.99700 61.07600 1.000 60.29000  ? 534 HOH A O    1 
HETATM 4988 O  O    . HOH L 5 .   ? 33.73300  -18.34600 53.15700 1.000 53.65000  ? 535 HOH A O    1 
HETATM 4989 O  O    . HOH L 5 .   ? 41.88800  -33.39300 32.91400 1.000 56.82000  ? 536 HOH A O    1 
HETATM 4990 O  O    . HOH L 5 .   ? 27.83900  -13.00400 19.33600 1.000 67.02000  ? 537 HOH A O    1 
HETATM 4991 O  O    . HOH L 5 .   ? 42.55600  -31.80000 54.04500 1.000 56.43000  ? 538 HOH A O    1 
HETATM 4992 O  O    . HOH L 5 .   ? 17.21100  -21.34600 43.85000 1.000 55.11000  ? 539 HOH A O    1 
HETATM 4993 O  O    . HOH L 5 .   ? 45.13300  -26.76700 35.51500 1.000 58.71000  ? 540 HOH A O    1 
HETATM 4994 O  O    . HOH L 5 .   ? 39.91100  -32.29300 26.25900 1.000 48.28000  ? 541 HOH A O    1 
HETATM 4995 O  O    . HOH L 5 .   ? 43.55600  -25.90800 25.99400 1.000 49.75000  ? 542 HOH A O    1 
HETATM 4996 O  O    . HOH L 5 .   ? 23.60600  -34.24900 37.29100 1.000 56.79000  ? 543 HOH A O    1 
HETATM 4997 O  O    . HOH L 5 .   ? 11.35400  -10.15800 21.58200 1.000 63.97000  ? 544 HOH A O    1 
HETATM 4998 O  O    . HOH L 5 .   ? 22.49400  -36.06500 35.60100 1.000 47.08000  ? 545 HOH A O    1 
HETATM 4999 O  O    . HOH L 5 .   ? 27.69900  -13.77600 37.86800 1.000 58.57000  ? 546 HOH A O    1 
HETATM 5000 O  O    . HOH L 5 .   ? 13.77700  -27.21300 19.32900 1.000 54.45000  ? 547 HOH A O    1 
HETATM 5001 O  O    . HOH L 5 .   ? 28.92900  -17.04400 43.54300 1.000 80.71000  ? 548 HOH A O    1 
HETATM 5002 O  O    . HOH L 5 .   ? 19.80500  -23.92400 52.70100 1.000 63.84000  ? 549 HOH A O    1 
HETATM 5003 O  O    . HOH L 5 .   ? 21.41400  -13.97100 23.71700 1.000 49.26000  ? 550 HOH A O    1 
HETATM 5004 O  O    . HOH L 5 .   ? 34.03600  -39.67900 42.97000 1.000 50.30000  ? 551 HOH A O    1 
HETATM 5005 O  O    . HOH L 5 .   ? 9.55300   -27.24200 31.59800 1.000 51.97000  ? 552 HOH A O    1 
HETATM 5006 O  O    . HOH L 5 .   ? 56.72100  -39.32100 58.13700 1.000 81.63000  ? 553 HOH A O    1 
HETATM 5007 O  O    . HOH L 5 .   ? 11.84200  -27.05700 32.66300 1.000 51.93000  ? 554 HOH A O    1 
HETATM 5008 O  O    . HOH L 5 .   ? 37.22400  -23.51100 47.57300 1.000 53.94000  ? 555 HOH A O    1 
HETATM 5009 O  O    . HOH L 5 .   ? 31.48900  -11.05400 21.36300 1.000 64.46000  ? 556 HOH A O    1 
HETATM 5010 O  O    . HOH L 5 .   ? 42.79600  -27.07100 40.89100 1.000 56.97000  ? 557 HOH A O    1 
HETATM 5011 O  O    . HOH L 5 .   ? 49.86800  -46.75800 57.94200 1.000 71.17000  ? 558 HOH A O    1 
HETATM 5012 O  O    . HOH L 5 .   ? 39.96500  -25.32800 49.61100 1.000 65.60000  ? 559 HOH A O    1 
HETATM 5013 O  O    . HOH L 5 .   ? 30.46600  -20.73700 56.33100 1.000 50.98000  ? 560 HOH A O    1 
HETATM 5014 O  O    . HOH L 5 .   ? 38.67400  -21.38200 48.87600 1.000 58.90000  ? 561 HOH A O    1 
HETATM 5015 O  O    . HOH L 5 .   ? 31.70500  -41.24600 45.89200 1.000 52.27000  ? 562 HOH A O    1 
HETATM 5016 O  O    . HOH L 5 .   ? 17.96700  -13.01500 39.48200 1.000 61.72000  ? 563 HOH A O    1 
HETATM 5017 O  O    . HOH L 5 .   ? 19.53800  -46.85000 21.63400 1.000 30.00000  ? 564 HOH A O    1 
HETATM 5018 O  O    . HOH L 5 .   ? 21.57500  -45.28600 19.38000 1.000 30.00000  ? 565 HOH A O    1 
HETATM 5019 O  O    . HOH L 5 .   ? 42.17800  -33.15300 25.33100 1.000 63.50000  ? 566 HOH A O    1 
HETATM 5020 O  O    . HOH L 5 .   ? 32.08500  -19.25400 55.04500 1.000 54.59000  ? 567 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . VAL A 3   ? 1.13210 1.39040 1.38450 0.18060  -0.40810 0.09270  3   VAL A N   
2    C CA  . VAL A 3   ? 1.09930 1.35050 1.39470 0.21540  -0.39170 0.07220  3   VAL A CA  
3    C C   . VAL A 3   ? 1.06140 1.37370 1.39710 0.21760  -0.35390 0.04130  3   VAL A C   
4    O O   . VAL A 3   ? 1.06270 1.40540 1.38150 0.18780  -0.33510 0.03630  3   VAL A O   
5    C CB  . VAL A 3   ? 1.09040 1.27650 1.34400 0.20880  -0.37640 0.07640  3   VAL A CB  
6    C CG1 . VAL A 3   ? 1.10320 1.30110 1.33000 0.18040  -0.33210 0.06200  3   VAL A CG1 
7    C CG2 . VAL A 3   ? 1.09530 1.25670 1.38610 0.24880  -0.37710 0.06170  3   VAL A CG2 
16   N N   . ARG A 4   ? 1.00230 1.33020 1.38850 0.25160  -0.34320 0.02010  4   ARG A N   
17   C CA  . ARG A 4   ? 0.92470 1.30650 1.34350 0.25060  -0.30510 -0.00760 4   ARG A CA  
18   C C   . ARG A 4   ? 0.87000 1.22020 1.24470 0.22800  -0.26830 -0.01430 4   ARG A C   
19   O O   . ARG A 4   ? 0.85520 1.14720 1.19670 0.22990  -0.26800 -0.00730 4   ARG A O   
20   C CB  . ARG A 4   ? 0.89520 1.29900 1.36940 0.28790  -0.29680 -0.02800 4   ARG A CB  
21   C CG  . ARG A 4   ? 0.92990 1.41430 1.45350 0.28590  -0.27270 -0.04940 4   ARG A CG  
22   C CD  . ARG A 4   ? 0.91370 1.41750 1.48420 0.31730  -0.26310 -0.06540 4   ARG A CD  
23   N NE  . ARG A 4   ? 0.97710 1.42400 1.52950 0.33790  -0.25210 -0.07520 4   ARG A NE  
24   C CZ  . ARG A 4   ? 0.97190 1.43360 1.53800 0.34840  -0.21910 -0.10120 4   ARG A CZ  
25   N NH1 . ARG A 4   ? 0.95280 1.48520 1.55120 0.33950  -0.19130 -0.11940 4   ARG A NH1 
26   N NH2 . ARG A 4   ? 0.95600 1.35930 1.49930 0.36500  -0.21430 -0.10880 4   ARG A NH2 
40   N N   . THR A 5   ? 0.76270 1.15050 1.13810 0.20570  -0.23950 -0.02730 5   THR A N   
41   C CA  . THR A 5   ? 0.75830 1.11760 1.09440 0.18490  -0.20840 -0.03290 5   THR A CA  
42   C C   . THR A 5   ? 0.69220 1.09450 1.05010 0.17650  -0.17770 -0.05300 5   THR A C   
43   O O   . THR A 5   ? 0.66290 1.12170 1.05870 0.17530  -0.17930 -0.06020 5   THR A O   
44   C CB  . THR A 5   ? 0.78190 1.11850 1.06720 0.15230  -0.21110 -0.01860 5   THR A CB  
45   O OG1 . THR A 5   ? 0.77690 1.15660 1.07000 0.13390  -0.21800 -0.01870 5   THR A OG1 
46   C CG2 . THR A 5   ? 0.81280 1.10480 1.06760 0.15350  -0.23840 0.00400  5   THR A CG2 
54   N N   . ILE A 6   ? 0.67910 1.05380 1.01160 0.16840  -0.15130 -0.06050 6   ILE A N   
55   C CA  . ILE A 6   ? 0.66710 1.06720 1.00400 0.15280  -0.12290 -0.07450 6   ILE A CA  
56   C C   . ILE A 6   ? 0.62670 0.98650 0.91690 0.12890  -0.10960 -0.07070 6   ILE A C   
57   O O   . ILE A 6   ? 0.61580 0.93260 0.87610 0.12930  -0.11580 -0.06150 6   ILE A O   
58   C CB  . ILE A 6   ? 0.66300 1.07450 1.02130 0.17190  -0.10350 -0.09090 6   ILE A CB  
59   C CG1 . ILE A 6   ? 0.63900 0.99170 0.96430 0.18110  -0.09830 -0.08990 6   ILE A CG1 
60   C CG2 . ILE A 6   ? 0.61720 1.07090 1.02780 0.20140  -0.11650 -0.09910 6   ILE A CG2 
61   C CD1 . ILE A 6   ? 0.71950 1.07640 1.05730 0.20040  -0.08140 -0.10750 6   ILE A CD1 
73   N N   . LYS A 7   ? 0.65450 1.02950 0.94070 0.10750  -0.09200 -0.07810 7   LYS A N   
74   C CA  . LYS A 7   ? 0.62310 0.96110 0.87150 0.08840  -0.07970 -0.07780 7   LYS A CA  
75   C C   . LYS A 7   ? 0.61030 0.92810 0.85060 0.09340  -0.06050 -0.08400 7   LYS A C   
76   O O   . LYS A 7   ? 0.63440 0.97920 0.89150 0.09160  -0.04740 -0.09180 7   LYS A O   
77   C CB  . LYS A 7   ? 0.66230 1.01740 0.90640 0.06120  -0.07630 -0.08150 7   LYS A CB  
78   C CG  . LYS A 7   ? 0.61400 0.92840 0.82350 0.04480  -0.06480 -0.08450 7   LYS A CG  
79   C CD  . LYS A 7   ? 0.66580 0.99140 0.87300 0.01830  -0.06080 -0.09060 7   LYS A CD  
80   C CE  . LYS A 7   ? 0.74020 1.08130 0.96070 0.01010  -0.04580 -0.09390 7   LYS A CE  
81   N NZ  . LYS A 7   ? 0.75410 1.10670 0.97340 -0.02020 -0.04440 -0.09760 7   LYS A NZ  
95   N N   . VAL A 8   ? 0.57840 0.85220 0.79200 0.09760  -0.05930 -0.08030 8   VAL A N   
96   C CA  . VAL A 8   ? 0.61840 0.86710 0.81700 0.09920  -0.04500 -0.08420 8   VAL A CA  
97   C C   . VAL A 8   ? 0.58040 0.79310 0.75120 0.08740  -0.04330 -0.08110 8   VAL A C   
98   O O   . VAL A 8   ? 0.56030 0.76790 0.72360 0.08150  -0.05090 -0.07800 8   VAL A O   
99   C CB  . VAL A 8   ? 0.58200 0.81470 0.78230 0.12160  -0.04790 -0.08530 8   VAL A CB  
100  C CG1 . VAL A 8   ? 0.61030 0.87780 0.84370 0.13970  -0.05310 -0.09120 8   VAL A CG1 
101  C CG2 . VAL A 8   ? 0.62670 0.82550 0.81080 0.12580  -0.06120 -0.07590 8   VAL A CG2 
111  N N   . PHE A 9   ? 0.57760 0.76720 0.73330 0.08460  -0.03350 -0.08300 9   PHE A N   
112  C CA  . PHE A 9   ? 0.54660 0.70270 0.68240 0.07830  -0.03340 -0.08160 9   PHE A CA  
113  C C   . PHE A 9   ? 0.55550 0.68600 0.68140 0.09040  -0.03530 -0.07900 9   PHE A C   
114  O O   . PHE A 9   ? 0.61810 0.74590 0.74040 0.09620  -0.03100 -0.08040 9   PHE A O   
115  C CB  . PHE A 9   ? 0.56290 0.70720 0.68730 0.06210  -0.02620 -0.08360 9   PHE A CB  
116  C CG  . PHE A 9   ? 0.60180 0.76940 0.73460 0.04570  -0.02510 -0.08660 9   PHE A CG  
117  C CD1 . PHE A 9   ? 0.56570 0.73210 0.69690 0.03900  -0.03140 -0.09030 9   PHE A CD1 
118  C CD2 . PHE A 9   ? 0.58740 0.78130 0.72890 0.03460  -0.01720 -0.08720 9   PHE A CD2 
119  C CE1 . PHE A 9   ? 0.59930 0.78520 0.73580 0.02150  -0.03270 -0.09390 9   PHE A CE1 
120  C CE2 . PHE A 9   ? 0.62770 0.84630 0.77930 0.01600  -0.01770 -0.08960 9   PHE A CE2 
121  C CZ  . PHE A 9   ? 0.61940 0.83140 0.76760 0.00940  -0.02700 -0.09270 9   PHE A CZ  
131  N N   . THR A 10  ? 0.52630 0.64150 0.64750 0.09240  -0.04120 -0.07670 10  THR A N   
132  C CA  . THR A 10  ? 0.55750 0.64990 0.67100 0.09970  -0.04490 -0.07410 10  THR A CA  
133  C C   . THR A 10  ? 0.56870 0.64030 0.67380 0.09560  -0.04390 -0.07560 10  THR A C   
134  O O   . THR A 10  ? 0.55640 0.62660 0.66130 0.08810  -0.04130 -0.07940 10  THR A O   
135  C CB  . THR A 10  ? 0.51930 0.61300 0.63660 0.10240  -0.05250 -0.06960 10  THR A CB  
136  O OG1 . THR A 10  ? 0.59610 0.70310 0.71580 0.09400  -0.05100 -0.07160 10  THR A OG1 
137  C CG2 . THR A 10  ? 0.57720 0.67710 0.69940 0.10970  -0.05940 -0.06530 10  THR A CG2 
145  N N   . THR A 11  ? 0.55440 0.60670 0.65220 0.10090  -0.04880 -0.07290 11  THR A N   
146  C CA  . THR A 11  ? 0.53760 0.56740 0.62860 0.09980  -0.05280 -0.07240 11  THR A CA  
147  C C   . THR A 11  ? 0.56710 0.58330 0.65470 0.10610  -0.06220 -0.06860 11  THR A C   
148  O O   . THR A 11  ? 0.58520 0.60340 0.66950 0.10910  -0.06410 -0.06720 11  THR A O   
149  C CB  . THR A 11  ? 0.56710 0.58260 0.64040 0.09080  -0.04900 -0.07010 11  THR A CB  
150  O OG1 . THR A 11  ? 0.62680 0.61460 0.69420 0.08930  -0.05680 -0.06830 11  THR A OG1 
151  C CG2 . THR A 11  ? 0.59060 0.60010 0.64540 0.09080  -0.04750 -0.06690 11  THR A CG2 
159  N N   . VAL A 12  ? 0.58380 0.58430 0.67350 0.10870  -0.07060 -0.06780 12  VAL A N   
160  C CA  . VAL A 12  ? 0.59580 0.58200 0.68070 0.11270  -0.08320 -0.06310 12  VAL A CA  
161  C C   . VAL A 12  ? 0.61440 0.57000 0.67940 0.11080  -0.09270 -0.05710 12  VAL A C   
162  O O   . VAL A 12  ? 0.64680 0.58710 0.69740 0.11100  -0.10450 -0.05150 12  VAL A O   
163  C CB  . VAL A 12  ? 0.55210 0.55520 0.66490 0.11860  -0.08970 -0.06610 12  VAL A CB  
164  C CG1 . VAL A 12  ? 0.62490 0.65240 0.74750 0.11490  -0.08310 -0.06720 12  VAL A CG1 
165  C CG2 . VAL A 12  ? 0.57790 0.58510 0.71010 0.12430  -0.08890 -0.07360 12  VAL A CG2 
175  N N   . ASP A 13  ? 0.63990 0.58220 0.70010 0.10670  -0.09030 -0.05690 13  ASP A N   
176  C CA  . ASP A 13  ? 0.64190 0.54740 0.67820 0.10160  -0.10200 -0.04760 13  ASP A CA  
177  C C   . ASP A 13  ? 0.67390 0.56930 0.68240 0.08430  -0.09120 -0.04300 13  ASP A C   
178  O O   . ASP A 13  ? 0.70180 0.56310 0.68320 0.07420  -0.10040 -0.03230 13  ASP A O   
179  C CB  . ASP A 13  ? 0.70440 0.59300 0.76120 0.11220  -0.11490 -0.05070 13  ASP A CB  
180  C CG  . ASP A 13  ? 0.67440 0.57270 0.74710 0.11170  -0.10320 -0.06230 13  ASP A CG  
181  O OD1 . ASP A 13  ? 0.67800 0.59300 0.74260 0.10010  -0.08770 -0.06410 13  ASP A OD1 
182  O OD2 . ASP A 13  ? 0.72090 0.61150 0.81520 0.12380  -0.11020 -0.07130 13  ASP A OD2 
187  N N   . ASN A 14  ? 0.67660 0.60190 0.69170 0.07910  -0.07360 -0.04960 14  ASN A N   
188  C CA  . ASN A 14  ? 0.73200 0.66270 0.73000 0.06140  -0.06070 -0.04750 14  ASN A CA  
189  C C   . ASN A 14  ? 0.70160 0.60770 0.69430 0.04940  -0.06470 -0.04420 14  ASN A C   
190  O O   . ASN A 14  ? 0.75110 0.65500 0.72450 0.02870  -0.05710 -0.03880 14  ASN A O   
191  C CB  . ASN A 14  ? 0.69670 0.61910 0.65940 0.05010  -0.05750 -0.04010 14  ASN A CB  
192  C CG  . ASN A 14  ? 0.81020 0.76490 0.76820 0.03640  -0.03690 -0.04440 14  ASN A CG  
193  O OD1 . ASN A 14  ? 0.74360 0.73480 0.72670 0.04570  -0.02650 -0.05500 14  ASN A OD1 
194  N ND2 . ASN A 14  ? 0.88840 0.83110 0.81520 0.01350  -0.03200 -0.03550 14  ASN A ND2 
201  N N   . ILE A 15  ? 0.68240 0.57070 0.69240 0.06090  -0.07620 -0.04880 15  ILE A N   
202  C CA  . ILE A 15  ? 0.64430 0.50550 0.65270 0.05280  -0.08090 -0.05080 15  ILE A CA  
203  C C   . ILE A 15  ? 0.72490 0.61330 0.76100 0.05910  -0.07250 -0.06740 15  ILE A C   
204  O O   . ILE A 15  ? 0.67570 0.57270 0.70940 0.04380  -0.06470 -0.07100 15  ILE A O   
205  C CB  . ILE A 15  ? 0.71020 0.52090 0.71330 0.06270  -0.10330 -0.04560 15  ILE A CB  
206  C CG1 . ILE A 15  ? 0.77920 0.56030 0.74680 0.05270  -0.11470 -0.02620 15  ILE A CG1 
207  C CG2 . ILE A 15  ? 0.65880 0.43230 0.65870 0.05550  -0.11020 -0.04990 15  ILE A CG2 
208  C CD1 . ILE A 15  ? 0.76490 0.49960 0.73070 0.06680  -0.14240 -0.01860 15  ILE A CD1 
220  N N   . ASN A 16  ? 0.64200 0.54750 0.70290 0.07880  -0.07410 -0.07720 16  ASN A N   
221  C CA  . ASN A 16  ? 0.66540 0.60020 0.74640 0.08260  -0.06510 -0.09240 16  ASN A CA  
222  C C   . ASN A 16  ? 0.60550 0.58300 0.69080 0.07830  -0.05370 -0.09010 16  ASN A C   
223  O O   . ASN A 16  ? 0.54570 0.53780 0.63630 0.08680  -0.05390 -0.08560 16  ASN A O   
224  C CB  . ASN A 16  ? 0.62840 0.56880 0.73320 0.10240  -0.06950 -0.10400 16  ASN A CB  
225  C CG  . ASN A 16  ? 0.68250 0.58110 0.79050 0.11240  -0.08310 -0.11030 16  ASN A CG  
226  O OD1 . ASN A 16  ? 0.83590 0.72390 0.95660 0.12820  -0.09520 -0.10850 16  ASN A OD1 
227  N ND2 . ASN A 16  ? 0.76690 0.63960 0.86460 0.10360  -0.08350 -0.11810 16  ASN A ND2 
234  N N   . LEU A 17  ? 0.56040 0.55540 0.64410 0.06530  -0.04640 -0.09330 17  LEU A N   
235  C CA  . LEU A 17  ? 0.59430 0.62830 0.68540 0.06330  -0.03940 -0.09120 17  LEU A CA  
236  C C   . LEU A 17  ? 0.62380 0.68140 0.72600 0.06650  -0.03800 -0.09980 17  LEU A C   
237  O O   . LEU A 17  ? 0.58870 0.63820 0.69060 0.06480  -0.03810 -0.11120 17  LEU A O   
238  C CB  . LEU A 17  ? 0.55200 0.59940 0.63860 0.04630  -0.03410 -0.08840 17  LEU A CB  
239  C CG  . LEU A 17  ? 0.63720 0.66250 0.70580 0.03450  -0.03290 -0.07980 17  LEU A CG  
240  C CD1 . LEU A 17  ? 0.64940 0.69950 0.71910 0.01380  -0.02530 -0.07880 17  LEU A CD1 
241  C CD2 . LEU A 17  ? 0.63420 0.65910 0.69620 0.04450  -0.03170 -0.07300 17  LEU A CD2 
253  N N   . HIS A 18  ? 0.54750 0.63170 0.65640 0.07050  -0.03730 -0.09490 18  HIS A N   
254  C CA  . HIS A 18  ? 0.59980 0.70650 0.71230 0.06940  -0.03750 -0.09830 18  HIS A CA  
255  C C   . HIS A 18  ? 0.57140 0.70360 0.68760 0.06520  -0.04040 -0.09180 18  HIS A C   
256  O O   . HIS A 18  ? 0.53900 0.67600 0.66090 0.07330  -0.04310 -0.08370 18  HIS A O   
257  C CB  . HIS A 18  ? 0.58670 0.69580 0.70350 0.07820  -0.03870 -0.09550 18  HIS A CB  
258  C CG  . HIS A 18  ? 0.59520 0.68630 0.71710 0.08600  -0.03830 -0.10180 18  HIS A CG  
259  N ND1 . HIS A 18  ? 0.62410 0.71710 0.75090 0.08720  -0.03430 -0.11620 18  HIS A ND1 
260  C CD2 . HIS A 18  ? 0.61360 0.68570 0.73790 0.09420  -0.04320 -0.09680 18  HIS A CD2 
261  C CE1 . HIS A 18  ? 0.63460 0.71190 0.77200 0.09850  -0.03780 -0.11950 18  HIS A CE1 
262  N NE2 . HIS A 18  ? 0.60600 0.66970 0.74040 0.10160  -0.04450 -0.10630 18  HIS A NE2 
270  N N   . THR A 19  ? 0.54790 0.69560 0.66180 0.05360  -0.04160 -0.09670 19  THR A N   
271  C CA  . THR A 19  ? 0.55950 0.73520 0.68190 0.05030  -0.04800 -0.09060 19  THR A CA  
272  C C   . THR A 19  ? 0.55030 0.73540 0.67360 0.05860  -0.05640 -0.08050 19  THR A C   
273  O O   . THR A 19  ? 0.57960 0.75900 0.69120 0.05690  -0.05660 -0.07980 19  THR A O   
274  C CB  . THR A 19  ? 0.58990 0.77980 0.70710 0.03370  -0.05090 -0.09780 19  THR A CB  
275  O OG1 . THR A 19  ? 0.60220 0.77140 0.71320 0.02380  -0.04490 -0.10750 19  THR A OG1 
276  C CG2 . THR A 19  ? 0.53090 0.75470 0.66470 0.03040  -0.05950 -0.09170 19  THR A CG2 
284  N N   . GLN A 20  ? 0.54930 0.74910 0.68740 0.06710  -0.06380 -0.07320 20  GLN A N   
285  C CA  . GLN A 20  ? 0.58760 0.78740 0.72630 0.07610  -0.07650 -0.06180 20  GLN A CA  
286  C C   . GLN A 20  ? 0.59670 0.82300 0.75460 0.08160  -0.08940 -0.05740 20  GLN A C   
287  O O   . GLN A 20  ? 0.62350 0.86850 0.80250 0.08670  -0.08450 -0.06360 20  GLN A O   
288  C CB  . GLN A 20  ? 0.60410 0.78090 0.74470 0.09050  -0.07510 -0.05870 20  GLN A CB  
289  C CG  . GLN A 20  ? 0.60980 0.76480 0.73820 0.08740  -0.06540 -0.06240 20  GLN A CG  
290  C CD  . GLN A 20  ? 0.61510 0.76940 0.72990 0.07720  -0.06690 -0.05890 20  GLN A CD  
291  O OE1 . GLN A 20  ? 0.59210 0.75510 0.69930 0.07100  -0.07670 -0.05010 20  GLN A OE1 
292  N NE2 . GLN A 20  ? 0.56180 0.70800 0.67370 0.07490  -0.05780 -0.06580 20  GLN A NE2 
301  N N   . VAL A 21  ? 0.60360 0.83390 0.75450 0.07960  -0.10660 -0.04620 21  VAL A N   
302  C CA  . VAL A 21  ? 0.68490 0.93590 0.85710 0.09040  -0.12570 -0.03900 21  VAL A CA  
303  C C   . VAL A 21  ? 0.72010 0.94400 0.89260 0.10790  -0.13890 -0.02810 21  VAL A C   
304  O O   . VAL A 21  ? 0.73580 0.93410 0.88180 0.09960  -0.14580 -0.01630 21  VAL A O   
305  C CB  . VAL A 21  ? 0.76950 1.03950 0.93010 0.07450  -0.14180 -0.03180 21  VAL A CB  
306  C CG1 . VAL A 21  ? 0.76120 1.04490 0.91110 0.05350  -0.12800 -0.04490 21  VAL A CG1 
307  C CG2 . VAL A 21  ? 0.89080 1.13730 1.01770 0.06550  -0.15420 -0.01610 21  VAL A CG2 
317  N N   . VAL A 22  ? 0.66580 0.89480 0.86720 0.13070  -0.14140 -0.03350 22  VAL A N   
318  C CA  . VAL A 22  ? 0.75150 0.94690 0.95340 0.14980  -0.15270 -0.02820 22  VAL A CA  
319  C C   . VAL A 22  ? 0.76140 0.96440 0.98660 0.16860  -0.18000 -0.02050 22  VAL A C   
320  O O   . VAL A 22  ? 0.75640 1.00190 1.01470 0.17720  -0.18280 -0.02790 22  VAL A O   
321  C CB  . VAL A 22  ? 0.70950 0.89740 0.92250 0.16460  -0.13460 -0.04430 22  VAL A CB  
322  C CG1 . VAL A 22  ? 0.70500 0.87390 0.89210 0.14840  -0.11590 -0.04700 22  VAL A CG1 
323  C CG2 . VAL A 22  ? 0.66770 0.90090 0.91390 0.17310  -0.12250 -0.05990 22  VAL A CG2 
333  N N   . ASP A 23  ? 0.83990 1.00140 1.04910 0.17430  -0.20200 -0.00500 23  ASP A N   
334  C CA  . ASP A 23  ? 0.83210 0.98620 1.06270 0.19740  -0.23310 0.00340  23  ASP A CA  
335  C C   . ASP A 23  ? 0.87020 1.02290 1.13590 0.23110  -0.22810 -0.01660 23  ASP A C   
336  O O   . ASP A 23  ? 0.90830 1.02220 1.15960 0.23660  -0.22010 -0.02260 23  ASP A O   
337  C CB  . ASP A 23  ? 0.91880 1.01900 1.11310 0.18780  -0.25910 0.02880  23  ASP A CB  
338  C CG  . ASP A 23  ? 0.96370 1.05030 1.17350 0.20780  -0.29860 0.04360  23  ASP A CG  
339  O OD1 . ASP A 23  ? 0.98660 1.08900 1.24200 0.24170  -0.30550 0.02870  23  ASP A OD1 
340  O OD2 . ASP A 23  ? 0.99100 1.05180 1.16730 0.18940  -0.32340 0.07010  23  ASP A OD2 
345  N N   . MET A 24  ? 0.84260 1.04140 1.15510 0.25300  -0.23220 -0.02900 24  MET A N   
346  C CA  . MET A 24  ? 0.84810 1.05620 1.19690 0.28590  -0.22330 -0.05320 24  MET A CA  
347  C C   . MET A 24  ? 0.85300 1.00260 1.20080 0.31330  -0.24980 -0.04990 24  MET A C   
348  O O   . MET A 24  ? 0.92830 1.06890 1.29080 0.33610  -0.23780 -0.07170 24  MET A O   
349  C CB  . MET A 24  ? 0.86150 1.14140 1.26750 0.30330  -0.22290 -0.06760 24  MET A CB  
350  C CG  . MET A 24  ? 0.81460 1.14920 1.22260 0.27330  -0.20700 -0.06620 24  MET A CG  
351  S SD  . MET A 24  ? 0.93600 1.36000 1.40420 0.28220  -0.18240 -0.09340 24  MET A SD  
352  C CE  . MET A 24  ? 0.82820 1.23740 1.29420 0.29960  -0.15060 -0.11950 24  MET A CE  
362  N N   . SER A 25  ? 0.84890 0.95460 1.17240 0.30620  -0.28290 -0.02270 25  SER A N   
363  C CA  . SER A 25  ? 0.93880 0.97760 1.25040 0.32240  -0.30700 -0.01480 25  SER A CA  
364  C C   . SER A 25  ? 0.96550 0.94000 1.23280 0.30810  -0.30740 -0.00750 25  SER A C   
365  O O   . SER A 25  ? 0.99030 0.90120 1.23870 0.31290  -0.32780 0.00190  25  SER A O   
366  C CB  . SER A 25  ? 0.93300 0.95340 1.23670 0.31800  -0.34400 0.01430  25  SER A CB  
367  O OG  . SER A 25  ? 0.90700 0.90090 1.16450 0.28580  -0.36040 0.04310  25  SER A OG  
373  N N   . MET A 26  ? 0.95030 0.94080 1.19250 0.27900  -0.27560 -0.01070 26  MET A N   
374  C CA  . MET A 26  ? 0.98480 0.92660 1.18640 0.25860  -0.26820 -0.00510 26  MET A CA  
375  C C   . MET A 26  ? 0.92950 0.88920 1.13530 0.26140  -0.23400 -0.03160 26  MET A C   
376  O O   . MET A 26  ? 0.91680 0.93140 1.14320 0.26270  -0.21020 -0.04650 26  MET A O   
377  C CB  . MET A 26  ? 1.02110 0.96440 1.18500 0.21760  -0.26550 0.01920  26  MET A CB  
378  C CG  . MET A 26  ? 1.08630 0.98220 1.22060 0.20310  -0.29930 0.05030  26  MET A CG  
379  S SD  . MET A 26  ? 1.08230 1.01120 1.18550 0.16240  -0.29720 0.07410  26  MET A SD  
380  C CE  . MET A 26  ? 1.08260 0.98450 1.14370 0.12530  -0.28170 0.08400  26  MET A CE  
390  N N   . THR A 27  ? 0.90530 0.81620 1.08810 0.25940  -0.23360 -0.03580 27  THR A N   
391  C CA  . THR A 27  ? 0.91430 0.83610 1.09210 0.25810  -0.20490 -0.05750 27  THR A CA  
392  C C   . THR A 27  ? 0.84200 0.79220 1.00210 0.22600  -0.18370 -0.04900 27  THR A C   
393  O O   . THR A 27  ? 0.84940 0.79680 0.99300 0.20250  -0.19110 -0.02770 27  THR A O   
394  C CB  . THR A 27  ? 0.94260 0.80240 1.09740 0.26170  -0.21380 -0.06370 27  THR A CB  
395  O OG1 . THR A 27  ? 0.95630 0.78110 1.07930 0.23110  -0.22620 -0.03890 27  THR A OG1 
396  C CG2 . THR A 27  ? 0.94520 0.76630 1.11620 0.29580  -0.23830 -0.07360 27  THR A CG2 
404  N N   . TYR A 28  ? 0.84590 0.82310 1.00850 0.22540  -0.15740 -0.06670 28  TYR A N   
405  C CA  . TYR A 28  ? 0.80670 0.80190 0.95360 0.19920  -0.14010 -0.06090 28  TYR A CA  
406  C C   . TYR A 28  ? 0.79290 0.75140 0.91330 0.17960  -0.14870 -0.04720 28  TYR A C   
407  O O   . TYR A 28  ? 0.80650 0.77980 0.91840 0.15780  -0.14280 -0.03630 28  TYR A O   
408  C CB  . TYR A 28  ? 0.75030 0.76570 0.89740 0.20170  -0.11610 -0.07970 28  TYR A CB  
409  C CG  . TYR A 28  ? 0.74900 0.81430 0.92110 0.20870  -0.10200 -0.08980 28  TYR A CG  
410  C CD1 . TYR A 28  ? 0.72970 0.82760 0.90750 0.19210  -0.09580 -0.08130 28  TYR A CD1 
411  C CD2 . TYR A 28  ? 0.74550 0.82780 0.93640 0.23050  -0.09440 -0.10980 28  TYR A CD2 
412  C CE1 . TYR A 28  ? 0.68990 0.83370 0.89080 0.19410  -0.08450 -0.08970 28  TYR A CE1 
413  C CE2 . TYR A 28  ? 0.72330 0.85930 0.94100 0.23330  -0.08050 -0.11880 28  TYR A CE2 
414  C CZ  . TYR A 28  ? 0.70850 0.87400 0.93080 0.21350  -0.07670 -0.10730 28  TYR A CZ  
415  O OH  . TYR A 28  ? 0.68420 0.90340 0.93320 0.21190  -0.06440 -0.11540 28  TYR A OH  
425  N N   . GLY A 29  ? 0.79890 0.71130 0.90770 0.18650  -0.16250 -0.04930 29  GLY A N   
426  C CA  . GLY A 29  ? 0.82170 0.70260 0.90800 0.16440  -0.17170 -0.03590 29  GLY A CA  
427  C C   . GLY A 29  ? 0.86660 0.74230 0.94500 0.14540  -0.18680 -0.01120 29  GLY A C   
428  O O   . GLY A 29  ? 0.87300 0.75550 0.93940 0.11930  -0.18330 0.00070  29  GLY A O   
432  N N   . GLN A 30  ? 0.83890 0.70530 0.92410 0.15760  -0.20430 -0.00320 30  GLN A N   
433  C CA  . GLN A 30  ? 0.90960 0.76900 0.98000 0.13690  -0.22090 0.02290  30  GLN A CA  
434  C C   . GLN A 30  ? 0.86420 0.77600 0.93430 0.11770  -0.20340 0.02810  30  GLN A C   
435  O O   . GLN A 30  ? 0.89210 0.80510 0.94240 0.09220  -0.20970 0.04770  30  GLN A O   
436  C CB  . GLN A 30  ? 0.85790 0.69440 0.93630 0.15730  -0.24790 0.03080  30  GLN A CB  
439  N N   . GLN A 31  ? 0.83000 0.78300 0.91870 0.12750  -0.18150 0.01030  31  GLN A N   
440  C CA  . GLN A 31  ? 0.81770 0.81500 0.90680 0.11260  -0.16630 0.01100  31  GLN A CA  
441  C C   . GLN A 31  ? 0.80230 0.81900 0.89090 0.10140  -0.14320 0.00030  31  GLN A C   
442  O O   . GLN A 31  ? 0.73040 0.76940 0.81080 0.08210  -0.13420 0.00430  31  GLN A O   
443  C CB  . GLN A 31  ? 0.78670 0.81550 0.89810 0.12950  -0.16300 0.00090  31  GLN A CB  
444  C CG  . GLN A 31  ? 0.82890 0.84380 0.95320 0.14980  -0.18710 0.00640  31  GLN A CG  
445  C CD  . GLN A 31  ? 0.84600 0.90430 0.99660 0.16140  -0.18520 -0.00150 31  GLN A CD  
446  O OE1 . GLN A 31  ? 0.82360 0.90890 0.96820 0.14530  -0.18500 0.00560  31  GLN A OE1 
447  N NE2 . GLN A 31  ? 0.83890 0.90720 1.01910 0.18810  -0.18310 -0.01790 31  GLN A NE2 
456  N N   . PHE A 32  ? 0.77140 0.78010 0.86780 0.11360  -0.13420 -0.01400 32  PHE A N   
457  C CA  . PHE A 32  ? 0.69030 0.71390 0.78780 0.10640  -0.11690 -0.02310 32  PHE A CA  
458  C C   . PHE A 32  ? 0.74240 0.74210 0.83260 0.10110  -0.12050 -0.02270 32  PHE A C   
459  O O   . PHE A 32  ? 0.73130 0.74450 0.82480 0.09390  -0.11060 -0.02740 32  PHE A O   
460  C CB  . PHE A 32  ? 0.72630 0.76440 0.83450 0.12010  -0.10340 -0.03860 32  PHE A CB  
461  C CG  . PHE A 32  ? 0.68630 0.75310 0.80510 0.12220  -0.09890 -0.04090 32  PHE A CG  
462  C CD1 . PHE A 32  ? 0.68900 0.77340 0.80410 0.10860  -0.10060 -0.03310 32  PHE A CD1 
463  C CD2 . PHE A 32  ? 0.67640 0.75610 0.80780 0.13520  -0.09240 -0.05160 32  PHE A CD2 
464  C CE1 . PHE A 32  ? 0.69790 0.80820 0.82110 0.10830  -0.09900 -0.03570 32  PHE A CE1 
465  C CE2 . PHE A 32  ? 0.74230 0.85270 0.88670 0.13420  -0.08960 -0.05350 32  PHE A CE2 
466  C CZ  . PHE A 32  ? 0.71420 0.83790 0.85410 0.12080  -0.09440 -0.04530 32  PHE A CZ  
476  N N   . GLY A 33  ? 0.80030 0.76370 0.88190 0.10470  -0.13660 -0.01800 33  GLY A N   
477  C CA  . GLY A 33  ? 0.73140 0.66910 0.80500 0.10070  -0.14170 -0.02090 33  GLY A CA  
478  C C   . GLY A 33  ? 0.73270 0.65950 0.80550 0.12010  -0.13620 -0.03860 33  GLY A C   
479  O O   . GLY A 33  ? 0.75980 0.69660 0.84000 0.13700  -0.13000 -0.04760 33  GLY A O   
483  N N   . PRO A 34  ? 0.73160 0.64190 0.79460 0.11600  -0.13830 -0.04420 34  PRO A N   
484  C CA  . PRO A 34  ? 0.74500 0.64480 0.79880 0.13090  -0.13220 -0.06120 34  PRO A CA  
485  C C   . PRO A 34  ? 0.71030 0.64420 0.77240 0.13740  -0.11360 -0.06780 34  PRO A C   
486  O O   . PRO A 34  ? 0.70660 0.66290 0.77480 0.12770  -0.10640 -0.06290 34  PRO A O   
487  C CB  . PRO A 34  ? 0.71960 0.60450 0.76060 0.11860  -0.13880 -0.06180 34  PRO A CB  
488  C CG  . PRO A 34  ? 0.79130 0.67100 0.83710 0.09950  -0.15170 -0.04660 34  PRO A CG  
489  C CD  . PRO A 34  ? 0.72960 0.63670 0.79010 0.09550  -0.14550 -0.03560 34  PRO A CD  
497  N N   . THR A 35  ? 0.71610 0.65450 0.78010 0.15360  -0.10620 -0.07990 35  THR A N   
498  C CA  . THR A 35  ? 0.71650 0.68890 0.78910 0.15620  -0.08900 -0.08500 35  THR A CA  
499  C C   . THR A 35  ? 0.72630 0.69690 0.78460 0.16440  -0.07790 -0.10140 35  THR A C   
500  O O   . THR A 35  ? 0.73890 0.69060 0.79080 0.17770  -0.08150 -0.11400 35  THR A O   
501  C CB  . THR A 35  ? 0.69200 0.68840 0.78720 0.16420  -0.08840 -0.08290 35  THR A CB  
502  O OG1 . THR A 35  ? 0.72240 0.71720 0.82250 0.15410  -0.09970 -0.06730 35  THR A OG1 
503  C CG2 . THR A 35  ? 0.70850 0.74200 0.81350 0.16070  -0.07180 -0.08670 35  THR A CG2 
511  N N   . TYR A 36  ? 0.67300 0.66160 0.72380 0.15540  -0.06450 -0.10190 36  TYR A N   
512  C CA  . TYR A 36  ? 0.70650 0.69710 0.73650 0.15640  -0.05150 -0.11500 36  TYR A CA  
513  C C   . TYR A 36  ? 0.68360 0.71140 0.72320 0.15070  -0.03390 -0.11610 36  TYR A C   
514  O O   . TYR A 36  ? 0.65820 0.69820 0.70880 0.14040  -0.03370 -0.10460 36  TYR A O   
515  C CB  . TYR A 36  ? 0.70940 0.67440 0.70780 0.14370  -0.05720 -0.11060 36  TYR A CB  
516  C CG  . TYR A 36  ? 0.67660 0.60950 0.66900 0.14380  -0.07650 -0.10740 36  TYR A CG  
517  C CD1 . TYR A 36  ? 0.69820 0.63030 0.70650 0.13590  -0.08840 -0.09260 36  TYR A CD1 
518  C CD2 . TYR A 36  ? 0.73500 0.64070 0.70610 0.15010  -0.08220 -0.12070 36  TYR A CD2 
519  C CE1 . TYR A 36  ? 0.68160 0.59060 0.68680 0.13140  -0.10520 -0.08870 36  TYR A CE1 
520  C CE2 . TYR A 36  ? 0.71990 0.59440 0.68460 0.14600  -0.10160 -0.11710 36  TYR A CE2 
521  C CZ  . TYR A 36  ? 0.74160 0.62010 0.72470 0.13520  -0.11300 -0.09980 36  TYR A CZ  
522  O OH  . TYR A 36  ? 0.82020 0.67370 0.79940 0.12670  -0.13160 -0.09520 36  TYR A OH  
532  N N   . LEU A 37  ? 0.69920 0.74640 0.73470 0.15640  -0.01840 -0.13190 37  LEU A N   
533  C CA  . LEU A 37  ? 0.69390 0.78130 0.73690 0.14660  0.00060  -0.13430 37  LEU A CA  
534  C C   . LEU A 37  ? 0.77680 0.85990 0.78020 0.13310  0.01430  -0.14020 37  LEU A C   
535  O O   . LEU A 37  ? 0.76400 0.85320 0.75620 0.14260  0.02460  -0.15920 37  LEU A O   
536  C CB  . LEU A 37  ? 0.65960 0.78810 0.73990 0.16390  0.00870  -0.14840 37  LEU A CB  
537  C CG  . LEU A 37  ? 0.69340 0.87430 0.78950 0.15180  0.02850  -0.15180 37  LEU A CG  
538  C CD1 . LEU A 37  ? 0.64400 0.82710 0.74470 0.13140  0.02340  -0.13260 37  LEU A CD1 
539  C CD2 . LEU A 37  ? 0.66320 0.88980 0.80410 0.17370  0.03330  -0.16810 37  LEU A CD2 
551  N N   . ASP A 38  ? 0.89260 0.96300 0.87260 0.11090  0.01330  -0.12450 38  ASP A N   
552  C CA  . ASP A 38  ? 1.00270 1.06290 0.93700 0.09290  0.02240  -0.12410 38  ASP A CA  
553  C C   . ASP A 38  ? 0.94980 0.97890 0.85270 0.10080  0.01490  -0.13400 38  ASP A C   
554  O O   . ASP A 38  ? 1.02320 1.05580 0.89100 0.09390  0.02810  -0.14570 38  ASP A O   
555  C CB  . ASP A 38  ? 1.15990 1.26690 1.09460 0.08280  0.04900  -0.13540 38  ASP A CB  
556  C CG  . ASP A 38  ? 1.37330 1.47280 1.26370 0.05090  0.05700  -0.12230 38  ASP A CG  
557  O OD1 . ASP A 38  ? 1.53390 1.67200 1.41510 0.03680  0.08090  -0.13130 38  ASP A OD1 
558  O OD2 . ASP A 38  ? 1.33780 1.39400 1.20330 0.03930  0.03870  -0.10280 38  ASP A OD2 
563  N N   . GLY A 39  ? 0.87400 0.87360 0.78720 0.11290  -0.00620 -0.12980 39  GLY A N   
564  C CA  . GLY A 39  ? 0.84520 0.81110 0.73090 0.11800  -0.01810 -0.13780 39  GLY A CA  
565  C C   . GLY A 39  ? 0.84850 0.81220 0.75090 0.14070  -0.01840 -0.15820 39  GLY A C   
566  O O   . GLY A 39  ? 0.84340 0.77180 0.73200 0.14520  -0.03500 -0.16180 39  GLY A O   
570  N N   . ALA A 40  ? 0.81690 0.81570 0.74990 0.15490  -0.00300 -0.17150 40  ALA A N   
571  C CA  . ALA A 40  ? 0.84000 0.83310 0.79200 0.18070  -0.00610 -0.19180 40  ALA A CA  
572  C C   . ALA A 40  ? 0.79340 0.76730 0.77620 0.18960  -0.02840 -0.17760 40  ALA A C   
573  O O   . ALA A 40  ? 0.80220 0.79640 0.81100 0.18410  -0.03040 -0.16070 40  ALA A O   
574  C CB  . ALA A 40  ? 0.74660 0.79010 0.72660 0.19510  0.01650  -0.21150 40  ALA A CB  
580  N N   . ASP A 41  ? 0.82860 0.76190 0.80460 0.20080  -0.04550 -0.18470 41  ASP A N   
581  C CA  . ASP A 41  ? 0.86360 0.77350 0.86050 0.20380  -0.06790 -0.16910 41  ASP A CA  
582  C C   . ASP A 41  ? 0.81000 0.73740 0.84510 0.22590  -0.06900 -0.17460 41  ASP A C   
583  O O   . ASP A 41  ? 0.88710 0.79900 0.92700 0.24840  -0.07210 -0.19490 41  ASP A O   
584  C CB  . ASP A 41  ? 0.87450 0.73060 0.84680 0.20250  -0.08780 -0.17280 41  ASP A CB  
585  C CG  . ASP A 41  ? 0.93130 0.76450 0.91810 0.19520  -0.11040 -0.15170 41  ASP A CG  
586  O OD1 . ASP A 41  ? 0.85790 0.70790 0.87390 0.20130  -0.11280 -0.14120 41  ASP A OD1 
587  O OD2 . ASP A 41  ? 1.01930 0.82010 0.98710 0.18090  -0.12600 -0.14500 41  ASP A OD2 
592  N N   . VAL A 42  ? 0.78740 0.74540 0.84960 0.22070  -0.06860 -0.15760 42  VAL A N   
593  C CA  . VAL A 42  ? 0.78190 0.75880 0.88080 0.23920  -0.07440 -0.15820 42  VAL A CA  
594  C C   . VAL A 42  ? 0.85140 0.79650 0.95550 0.23600  -0.10010 -0.13750 42  VAL A C   
595  O O   . VAL A 42  ? 0.86890 0.83060 0.99860 0.24280  -0.10860 -0.12840 42  VAL A O   
596  C CB  . VAL A 42  ? 0.76060 0.79550 0.88430 0.23360  -0.05820 -0.15460 42  VAL A CB  
597  C CG1 . VAL A 42  ? 0.73150 0.79950 0.84770 0.23200  -0.03200 -0.17330 42  VAL A CG1 
598  C CG2 . VAL A 42  ? 0.70980 0.74870 0.82680 0.20850  -0.06030 -0.13130 42  VAL A CG2 
608  N N   . THR A 43  ? 0.85270 0.75420 0.93120 0.22310  -0.11330 -0.12910 43  THR A N   
609  C CA  . THR A 43  ? 0.85470 0.73000 0.93380 0.21260  -0.13520 -0.10730 43  THR A CA  
610  C C   . THR A 43  ? 0.91140 0.76340 1.00600 0.23370  -0.15450 -0.10790 43  THR A C   
611  O O   . THR A 43  ? 0.90290 0.75730 1.00770 0.22840  -0.16800 -0.08820 43  THR A O   
612  C CB  . THR A 43  ? 0.84180 0.67660 0.89360 0.19490  -0.14620 -0.10160 43  THR A CB  
613  O OG1 . THR A 43  ? 0.82660 0.68340 0.86780 0.17870  -0.13200 -0.10060 43  THR A OG1 
614  C CG2 . THR A 43  ? 0.79950 0.61460 0.85060 0.17740  -0.16550 -0.07740 43  THR A CG2 
622  N N   . LYS A 44  ? 0.94020 0.76770 1.03490 0.25820  -0.15750 -0.13080 44  LYS A N   
623  C CA  . LYS A 44  ? 0.98440 0.78160 1.09580 0.28380  -0.17970 -0.13430 44  LYS A CA  
624  C C   . LYS A 44  ? 0.99150 0.83780 1.14300 0.31200  -0.17060 -0.14900 44  LYS A C   
625  O O   . LYS A 44  ? 0.96100 0.78760 1.13410 0.33950  -0.19020 -0.15470 44  LYS A O   
626  C CB  . LYS A 44  ? 1.05430 0.79090 1.14560 0.29810  -0.19120 -0.15480 44  LYS A CB  
627  C CG  . LYS A 44  ? 1.10690 0.78580 1.16380 0.27090  -0.21060 -0.13750 44  LYS A CG  
628  C CD  . LYS A 44  ? 1.21960 0.84990 1.24910 0.27760  -0.21360 -0.16290 44  LYS A CD  
629  C CE  . LYS A 44  ? 1.31330 0.86640 1.31950 0.26420  -0.24610 -0.14970 44  LYS A CE  
630  N NZ  . LYS A 44  ? 1.27400 0.78340 1.24600 0.25780  -0.24870 -0.17030 44  LYS A NZ  
644  N N   . ILE A 45  ? 0.99000 0.89900 1.15380 0.30540  -0.14350 -0.15490 45  ILE A N   
645  C CA  . ILE A 45  ? 0.92230 0.88910 1.12750 0.32690  -0.13210 -0.16920 45  ILE A CA  
646  C C   . ILE A 45  ? 0.89270 0.88910 1.11860 0.31670  -0.14310 -0.14420 45  ILE A C   
647  O O   . ILE A 45  ? 0.87900 0.86980 1.08410 0.28790  -0.14520 -0.12080 45  ILE A O   
648  C CB  . ILE A 45  ? 0.96980 0.98710 1.17240 0.31990  -0.09680 -0.18850 45  ILE A CB  
649  C CG1 . ILE A 45  ? 1.00400 1.01160 1.20260 0.34400  -0.08560 -0.22320 45  ILE A CG1 
650  C CG2 . ILE A 45  ? 0.93530 1.02560 1.17600 0.31980  -0.08280 -0.18850 45  ILE A CG2 
651  C CD1 . ILE A 45  ? 1.01800 1.06130 1.19590 0.32940  -0.05220 -0.23940 45  ILE A CD1 
663  N N   . LYS A 46  ? 0.94400 0.97550 1.21310 0.34150  -0.15060 -0.15110 46  LYS A N   
664  C CA  . LYS A 46  ? 0.87730 0.94350 1.16620 0.33170  -0.16140 -0.13000 46  LYS A CA  
665  C C   . LYS A 46  ? 0.85720 0.99850 1.16870 0.32190  -0.13370 -0.13960 46  LYS A C   
666  O O   . LYS A 46  ? 0.87930 1.05480 1.20710 0.33400  -0.11080 -0.16510 46  LYS A O   
667  C CB  . LYS A 46  ? 0.94230 1.00040 1.26060 0.35620  -0.18970 -0.12520 46  LYS A CB  
668  C CG  . LYS A 46  ? 0.99730 0.98820 1.28840 0.34890  -0.22470 -0.09740 46  LYS A CG  
669  C CD  . LYS A 46  ? 0.97470 0.92230 1.27210 0.37070  -0.24530 -0.10040 46  LYS A CD  
670  C CE  . LYS A 46  ? 1.07190 0.95470 1.34030 0.35830  -0.28190 -0.06860 46  LYS A CE  
671  N NZ  . LYS A 46  ? 1.13750 0.98900 1.41950 0.37940  -0.30710 -0.06630 46  LYS A NZ  
685  N N   . PRO A 47  ? 0.82140 0.98930 1.13180 0.29770  -0.13480 -0.12030 47  PRO A N   
686  C CA  . PRO A 47  ? 0.80210 1.03180 1.12660 0.28170  -0.10930 -0.12760 47  PRO A CA  
687  C C   . PRO A 47  ? 0.78260 1.07510 1.16070 0.30470  -0.10400 -0.14710 47  PRO A C   
688  O O   . PRO A 47  ? 0.76550 1.06860 1.17810 0.32760  -0.12810 -0.14500 47  PRO A O   
689  C CB  . PRO A 47  ? 0.79730 1.03260 1.10980 0.25480  -0.11910 -0.10400 47  PRO A CB  
690  C CG  . PRO A 47  ? 0.82260 0.99790 1.10290 0.24970  -0.14050 -0.08490 47  PRO A CG  
691  C CD  . PRO A 47  ? 0.84650 0.98710 1.13720 0.28030  -0.15820 -0.09190 47  PRO A CD  
699  N N   . HIS A 48  ? 0.84650 1.18270 1.23160 0.29750  -0.07310 -0.16530 48  HIS A N   
700  C CA  . HIS A 48  ? 0.84680 1.25920 1.28500 0.31120  -0.06100 -0.18470 48  HIS A CA  
701  C C   . HIS A 48  ? 0.76950 1.23350 1.22090 0.28160  -0.05590 -0.17260 48  HIS A C   
702  O O   . HIS A 48  ? 0.74110 1.17990 1.15490 0.25040  -0.05450 -0.15460 48  HIS A O   
703  C CB  . HIS A 48  ? 0.82710 1.26390 1.26250 0.31510  -0.02750 -0.21220 48  HIS A CB  
704  C CG  . HIS A 48  ? 0.91200 1.29400 1.32580 0.33920  -0.02980 -0.22690 48  HIS A CG  
705  N ND1 . HIS A 48  ? 0.98900 1.37870 1.38570 0.34080  -0.00160 -0.25140 48  HIS A ND1 
706  C CD2 . HIS A 48  ? 0.99130 1.30430 1.39000 0.35600  -0.05720 -0.21840 48  HIS A CD2 
707  C CE1 . HIS A 48  ? 1.05000 1.37770 1.42340 0.35910  -0.01230 -0.25910 48  HIS A CE1 
708  N NE2 . HIS A 48  ? 1.06060 1.34030 1.43580 0.36790  -0.04610 -0.23890 48  HIS A NE2 
716  N N   . ASN A 49  ? 0.74670 1.28510 1.25450 0.29210  -0.05360 -0.18480 49  ASN A N   
717  C CA  . ASN A 49  ? 0.72740 1.31990 1.24960 0.26080  -0.04710 -0.17660 49  ASN A CA  
718  C C   . ASN A 49  ? 0.65830 1.26050 1.14920 0.22660  -0.01290 -0.18060 49  ASN A C   
719  O O   . ASN A 49  ? 0.67140 1.27310 1.14180 0.19180  -0.01060 -0.16620 49  ASN A O   
720  C CB  . ASN A 49  ? 0.71420 1.38060 1.30030 0.27460  -0.05130 -0.18650 49  ASN A CB  
721  C CG  . ASN A 49  ? 0.77180 1.41350 1.37430 0.29620  -0.08950 -0.17120 49  ASN A CG  
722  O OD1 . ASN A 49  ? 0.85000 1.48540 1.47550 0.32530  -0.09690 -0.17840 49  ASN A OD1 
723  N ND2 . ASN A 49  ? 0.79350 1.42040 1.38180 0.28100  -0.11450 -0.15000 49  ASN A ND2 
730  N N   . SER A 50  ? 0.68910 1.29580 1.17220 0.23520  0.01220  -0.20010 50  SER A N   
731  C CA  . SER A 50  ? 0.67730 1.28500 1.12200 0.20160  0.04200  -0.20100 50  SER A CA  
732  C C   . SER A 50  ? 0.64670 1.17530 1.02790 0.18000  0.03600  -0.18050 50  SER A C   
733  O O   . SER A 50  ? 0.63830 1.15870 0.98480 0.14910  0.05350  -0.17510 50  SER A O   
734  C CB  . SER A 50  ? 0.69450 1.32120 1.13830 0.21680  0.06840  -0.22730 50  SER A CB  
735  O OG  . SER A 50  ? 0.72750 1.27920 1.12470 0.22930  0.06330  -0.22750 50  SER A OG  
741  N N   . HIS A 51  ? 0.68510 1.15690 1.05130 0.19480  0.01090  -0.16850 51  HIS A N   
742  C CA  . HIS A 51  ? 0.66560 1.07110 0.97990 0.17710  0.00520  -0.15150 51  HIS A CA  
743  C C   . HIS A 51  ? 0.66040 1.06330 0.96700 0.15070  -0.00370 -0.13400 51  HIS A C   
744  O O   . HIS A 51  ? 0.67930 1.03460 0.94800 0.13570  -0.00630 -0.12240 51  HIS A O   
745  C CB  . HIS A 51  ? 0.65820 1.00820 0.95940 0.20040  -0.01560 -0.14700 51  HIS A CB  
746  C CG  . HIS A 51  ? 0.70500 1.03480 0.99600 0.22110  -0.00770 -0.16400 51  HIS A CG  
747  N ND1 . HIS A 51  ? 0.72820 1.00580 1.00690 0.24100  -0.02600 -0.16280 51  HIS A ND1 
748  C CD2 . HIS A 51  ? 0.73010 1.08360 1.01740 0.22240  0.01660  -0.18350 51  HIS A CD2 
749  C CE1 . HIS A 51  ? 0.80370 1.07080 1.07230 0.25550  -0.01460 -0.18250 51  HIS A CE1 
750  N NE2 . HIS A 51  ? 0.82230 1.13660 1.09480 0.24510  0.01230  -0.19610 51  HIS A NE2 
758  N N   . GLU A 52  ? 0.69040 1.14410 1.03300 0.14520  -0.00900 -0.13380 52  GLU A N   
759  C CA  . GLU A 52  ? 0.68410 1.13290 1.01660 0.12020  -0.01920 -0.12020 52  GLU A CA  
760  C C   . GLU A 52  ? 0.66110 1.09200 0.96010 0.08800  -0.00240 -0.11670 52  GLU A C   
761  O O   . GLU A 52  ? 0.69490 1.15330 0.99660 0.07510  0.01760  -0.12370 52  GLU A O   
762  C CB  . GLU A 52  ? 0.69060 1.20270 1.06900 0.11790  -0.02860 -0.12240 52  GLU A CB  
763  C CG  . GLU A 52  ? 0.77280 1.28070 1.13850 0.09050  -0.04050 -0.11120 52  GLU A CG  
764  C CD  . GLU A 52  ? 0.82240 1.35110 1.21270 0.10140  -0.06820 -0.10500 52  GLU A CD  
765  O OE1 . GLU A 52  ? 0.87510 1.46180 1.31480 0.11520  -0.07480 -0.11150 52  GLU A OE1 
766  O OE2 . GLU A 52  ? 0.77070 1.26020 1.13100 0.09590  -0.08380 -0.09380 52  GLU A OE2 
773  N N   . GLY A 53  ? 0.63110 1.01530 0.89790 0.07480  -0.01100 -0.10610 53  GLY A N   
774  C CA  . GLY A 53  ? 0.60960 0.96620 0.84490 0.04760  -0.00130 -0.10190 53  GLY A CA  
775  C C   . GLY A 53  ? 0.64450 0.96000 0.84720 0.04930  0.00910  -0.10080 53  GLY A C   
776  O O   . GLY A 53  ? 0.65920 0.94240 0.83310 0.02900  0.01260  -0.09500 53  GLY A O   
780  N N   . LYS A 54  ? 0.63780 0.94980 0.84240 0.07260  0.01140  -0.10620 54  LYS A N   
781  C CA  . LYS A 54  ? 0.65230 0.92760 0.82360 0.07300  0.01930  -0.10580 54  LYS A CA  
782  C C   . LYS A 54  ? 0.61720 0.83840 0.76530 0.07930  0.00530  -0.09740 54  LYS A C   
783  O O   . LYS A 54  ? 0.57940 0.79470 0.73800 0.08840  -0.00810 -0.09410 54  LYS A O   
784  C CB  . LYS A 54  ? 0.62440 0.91800 0.80520 0.09430  0.02790  -0.11890 54  LYS A CB  
785  C CG  . LYS A 54  ? 0.68380 1.02320 0.87010 0.08190  0.05070  -0.12910 54  LYS A CG  
786  C CD  . LYS A 54  ? 0.74190 1.11330 0.95150 0.10900  0.05930  -0.14880 54  LYS A CD  
787  C CE  . LYS A 54  ? 0.79850 1.22050 1.00980 0.09550  0.08710  -0.16230 54  LYS A CE  
788  N NZ  . LYS A 54  ? 0.93140 1.35970 1.12090 0.05470  0.09750  -0.14910 54  LYS A NZ  
802  N N   . THR A 55  ? 0.57370 0.75850 0.68970 0.07270  0.00810  -0.09340 55  THR A N   
803  C CA  . THR A 55  ? 0.58920 0.72910 0.68740 0.07750  -0.00430 -0.08650 55  THR A CA  
804  C C   . THR A 55  ? 0.56250 0.68680 0.65420 0.09580  -0.00850 -0.08990 55  THR A C   
805  O O   . THR A 55  ? 0.63080 0.75860 0.71050 0.09830  0.00040  -0.09640 55  THR A O   
806  C CB  . THR A 55  ? 0.62160 0.72820 0.69100 0.06020  -0.00430 -0.07880 55  THR A CB  
807  O OG1 . THR A 55  ? 0.67150 0.78500 0.74460 0.04150  -0.00230 -0.07640 55  THR A OG1 
808  C CG2 . THR A 55  ? 0.59680 0.66520 0.65710 0.06850  -0.01820 -0.07380 55  THR A CG2 
816  N N   . PHE A 56  ? 0.59930 0.70690 0.69650 0.10610  -0.02150 -0.08630 56  PHE A N   
817  C CA  . PHE A 56  ? 0.55270 0.64020 0.64350 0.12000  -0.02920 -0.08800 56  PHE A CA  
818  C C   . PHE A 56  ? 0.60410 0.66130 0.68220 0.11640  -0.03950 -0.08050 56  PHE A C   
819  O O   . PHE A 56  ? 0.60760 0.66560 0.69390 0.11110  -0.04330 -0.07560 56  PHE A O   
820  C CB  . PHE A 56  ? 0.54470 0.64260 0.65690 0.13400  -0.03780 -0.08920 56  PHE A CB  
821  C CG  . PHE A 56  ? 0.60270 0.73300 0.73550 0.14430  -0.03140 -0.09880 56  PHE A CG  
822  C CD1 . PHE A 56  ? 0.60460 0.77080 0.75790 0.13760  -0.02730 -0.09830 56  PHE A CD1 
823  C CD2 . PHE A 56  ? 0.64030 0.76710 0.77440 0.16140  -0.03020 -0.11060 56  PHE A CD2 
824  C CE1 . PHE A 56  ? 0.59470 0.79950 0.77490 0.14810  -0.02240 -0.10810 56  PHE A CE1 
825  C CE2 . PHE A 56  ? 0.64110 0.80410 0.80180 0.17490  -0.02390 -0.12290 56  PHE A CE2 
826  C CZ  . PHE A 56  ? 0.62700 0.83250 0.81350 0.16840  -0.02010 -0.12090 56  PHE A CZ  
836  N N   . TYR A 57  ? 0.62850 0.66230 0.68820 0.11950  -0.04400 -0.08150 57  TYR A N   
837  C CA  . TYR A 57  ? 0.56460 0.57620 0.61890 0.11760  -0.05640 -0.07510 57  TYR A CA  
838  C C   . TYR A 57  ? 0.59890 0.60910 0.66660 0.12320  -0.06610 -0.07310 57  TYR A C   
839  O O   . TYR A 57  ? 0.66630 0.67330 0.73470 0.13150  -0.06810 -0.07730 57  TYR A O   
840  C CB  . TYR A 57  ? 0.63420 0.62170 0.66110 0.11560  -0.06080 -0.07580 57  TYR A CB  
841  C CG  . TYR A 57  ? 0.61630 0.59380 0.62350 0.10490  -0.05850 -0.07070 57  TYR A CG  
842  C CD1 . TYR A 57  ? 0.65750 0.64640 0.65290 0.09680  -0.04420 -0.07310 57  TYR A CD1 
843  C CD2 . TYR A 57  ? 0.60830 0.56530 0.60970 0.10190  -0.07250 -0.06260 57  TYR A CD2 
844  C CE1 . TYR A 57  ? 0.65690 0.63010 0.62840 0.08260  -0.04430 -0.06490 57  TYR A CE1 
845  C CE2 . TYR A 57  ? 0.68480 0.62410 0.66530 0.09240  -0.07540 -0.05520 57  TYR A CE2 
846  C CZ  . TYR A 57  ? 0.71030 0.65420 0.67240 0.08100  -0.06150 -0.05510 57  TYR A CZ  
847  O OH  . TYR A 57  ? 0.72600 0.64580 0.66170 0.06730  -0.06640 -0.04440 57  TYR A OH  
857  N N   . VAL A 58  ? 0.57980 0.59200 0.65820 0.11830  -0.07240 -0.06700 58  VAL A N   
858  C CA  . VAL A 58  ? 0.61710 0.62970 0.70460 0.11670  -0.08100 -0.06220 58  VAL A CA  
859  C C   . VAL A 58  ? 0.60920 0.61900 0.70140 0.11060  -0.08870 -0.05870 58  VAL A C   
860  O O   . VAL A 58  ? 0.60470 0.61560 0.69920 0.11070  -0.08830 -0.06010 58  VAL A O   
861  C CB  . VAL A 58  ? 0.60220 0.63690 0.70310 0.11320  -0.07740 -0.05880 58  VAL A CB  
862  C CG1 . VAL A 58  ? 0.60160 0.64380 0.70400 0.12040  -0.07380 -0.06160 58  VAL A CG1 
863  C CG2 . VAL A 58  ? 0.59400 0.64560 0.70350 0.10780  -0.07000 -0.06130 58  VAL A CG2 
873  N N   . LEU A 59  ? 0.68310 0.68950 0.77860 0.10460  -0.09780 -0.05350 59  LEU A N   
874  C CA  . LEU A 59  ? 0.71160 0.72630 0.81900 0.09660  -0.10490 -0.05060 59  LEU A CA  
875  C C   . LEU A 59  ? 0.70840 0.75710 0.83790 0.09220  -0.09610 -0.05140 59  LEU A C   
876  O O   . LEU A 59  ? 0.72750 0.78890 0.85720 0.08870  -0.08850 -0.05000 59  LEU A O   
877  C CB  . LEU A 59  ? 0.72970 0.73160 0.83300 0.08630  -0.11720 -0.04420 59  LEU A CB  
878  C CG  . LEU A 59  ? 0.81430 0.78950 0.90340 0.08570  -0.13070 -0.04630 59  LEU A CG  
879  C CD1 . LEU A 59  ? 0.84450 0.78850 0.90810 0.09680  -0.13030 -0.05350 59  LEU A CD1 
880  C CD2 . LEU A 59  ? 0.90670 0.87730 0.99960 0.06900  -0.14410 -0.03920 59  LEU A CD2 
892  N N   . PRO A 60  ? 0.75200 0.81660 0.90030 0.09330  -0.09770 -0.05510 60  PRO A N   
893  C CA  . PRO A 60  ? 0.74590 0.84590 0.91750 0.09140  -0.08730 -0.06100 60  PRO A CA  
894  C C   . PRO A 60  ? 0.82760 0.95170 1.00380 0.07470  -0.08350 -0.05550 60  PRO A C   
895  O O   . PRO A 60  ? 0.89120 1.03050 1.08090 0.06420  -0.08940 -0.05180 60  PRO A O   
896  C CB  . PRO A 60  ? 0.72250 0.83370 0.91840 0.09910  -0.09440 -0.06660 60  PRO A CB  
897  C CG  . PRO A 60  ? 0.79430 0.86920 0.97100 0.10550  -0.10790 -0.06220 60  PRO A CG  
898  C CD  . PRO A 60  ? 0.79440 0.84610 0.94380 0.09810  -0.11020 -0.05550 60  PRO A CD  
906  N N   . ASN A 61  ? 0.80890 0.93730 0.97230 0.06920  -0.07520 -0.05330 61  ASN A N   
907  C CA  . ASN A 61  ? 0.88240 1.02780 1.04030 0.04970  -0.07320 -0.04410 61  ASN A CA  
908  C C   . ASN A 61  ? 0.87880 1.06510 1.04530 0.04250  -0.05670 -0.05300 61  ASN A C   
909  O O   . ASN A 61  ? 0.93310 1.13520 1.08730 0.02310  -0.05300 -0.04480 61  ASN A O   
910  C CB  . ASN A 61  ? 0.97300 1.08820 1.10470 0.04730  -0.08150 -0.03220 61  ASN A CB  
911  C CG  . ASN A 61  ? 0.99150 1.10910 1.11520 0.05530  -0.07440 -0.03700 61  ASN A CG  
912  O OD1 . ASN A 61  ? 1.02600 1.17010 1.14890 0.04710  -0.06430 -0.04070 61  ASN A OD1 
913  N ND2 . ASN A 61  ? 1.00390 1.09720 1.12150 0.06980  -0.07910 -0.03830 61  ASN A ND2 
920  N N   . ASP A 62  ? 0.82320 1.02350 1.00680 0.05680  -0.04760 -0.07000 62  ASP A N   
921  C CA  . ASP A 62  ? 0.76340 1.00270 0.95680 0.05270  -0.03070 -0.08470 62  ASP A CA  
922  C C   . ASP A 62  ? 0.66740 0.92020 0.89350 0.07170  -0.02720 -0.10370 62  ASP A C   
923  O O   . ASP A 62  ? 0.71910 0.94410 0.95230 0.08710  -0.03930 -0.10260 62  ASP A O   
924  C CB  . ASP A 62  ? 0.76790 0.99950 0.93680 0.05110  -0.02450 -0.08780 62  ASP A CB  
925  C CG  . ASP A 62  ? 0.79680 0.99720 0.96360 0.06920  -0.02860 -0.09450 62  ASP A CG  
926  O OD1 . ASP A 62  ? 0.77150 0.96460 0.95710 0.08440  -0.03010 -0.10470 62  ASP A OD1 
927  O OD2 . ASP A 62  ? 0.81800 1.00200 0.96450 0.06680  -0.03190 -0.08830 62  ASP A OD2 
932  N N   . ASP A 63  ? 0.79160 0.98430 0.65760 0.12550  0.02020  0.02280  63  ASP A N   
933  C CA  . ASP A 63  ? 0.83840 1.02320 0.70990 0.11950  0.02230  0.00740  63  ASP A CA  
934  C C   . ASP A 63  ? 0.78700 0.96990 0.66650 0.11200  0.00980  -0.00480 63  ASP A C   
935  O O   . ASP A 63  ? 0.71730 0.88820 0.61040 0.10870  0.01180  -0.01250 63  ASP A O   
936  C CB  . ASP A 63  ? 0.79760 0.98390 0.64390 0.12330  0.02680  0.00080  63  ASP A CB  
937  C CG  . ASP A 63  ? 0.83660 1.02530 0.67950 0.12670  0.04270  0.01040  63  ASP A CG  
938  O OD1 . ASP A 63  ? 0.76970 0.95380 0.62730 0.12270  0.04980  0.02100  63  ASP A OD1 
939  O OD2 . ASP A 63  ? 0.89700 1.09090 0.71940 0.13160  0.04870  0.00730  63  ASP A OD2 
944  N N   . THR A 64  ? 0.76150 0.95850 0.63110 0.10780  -0.00310 -0.00590 64  THR A N   
945  C CA  . THR A 64  ? 0.68710 0.88250 0.55970 0.09470  -0.01500 -0.01720 64  THR A CA  
946  C C   . THR A 64  ? 0.71040 0.90600 0.61310 0.09280  -0.01470 -0.01250 64  THR A C   
947  O O   . THR A 64  ? 0.66340 0.84230 0.57210 0.08490  -0.01630 -0.02250 64  THR A O   
948  C CB  . THR A 64  ? 0.67570 0.89750 0.53390 0.08620  -0.02960 -0.01670 64  THR A CB  
949  O OG1 . THR A 64  ? 0.84380 1.06080 0.66880 0.08650  -0.03030 -0.02320 64  THR A OG1 
950  C CG2 . THR A 64  ? 0.60000 0.82170 0.45930 0.06620  -0.04170 -0.02760 64  THR A CG2 
958  N N   . LEU A 65  ? 0.72050 0.93040 0.63740 0.10180  -0.01190 0.00310  65  LEU A N   
959  C CA  . LEU A 65  ? 0.65740 0.86490 0.59820 0.10200  -0.01030 0.00770  65  LEU A CA  
960  C C   . LEU A 65  ? 0.64500 0.82540 0.59550 0.10160  0.00040  0.00380  65  LEU A C   
961  O O   . LEU A 65  ? 0.60900 0.78120 0.57480 0.09620  -0.00070 -0.00080 65  LEU A O   
962  C CB  . LEU A 65  ? 0.63570 0.85760 0.58020 0.11640  -0.00760 0.02570  65  LEU A CB  
963  C CG  . LEU A 65  ? 0.65460 0.91800 0.59710 0.11980  -0.01940 0.03270  65  LEU A CG  
964  C CD1 . LEU A 65  ? 0.66610 0.93860 0.60490 0.14290  -0.01340 0.05270  65  LEU A CD1 
965  C CD2 . LEU A 65  ? 0.59880 0.88390 0.55870 0.10580  -0.02980 0.02630  65  LEU A CD2 
977  N N   . ARG A 66  ? 0.64630 0.81730 0.58780 0.10600  0.01060  0.00620  66  ARG A N   
978  C CA  . ARG A 66  ? 0.65410 0.81150 0.60590 0.10340  0.01990  0.00320  66  ARG A CA  
979  C C   . ARG A 66  ? 0.62510 0.77660 0.58020 0.09990  0.01620  -0.01130 66  ARG A C   
980  O O   . ARG A 66  ? 0.62030 0.76480 0.59070 0.09730  0.01770  -0.01380 66  ARG A O   
981  C CB  . ARG A 66  ? 0.68090 0.83920 0.62120 0.10550  0.03120  0.00830  66  ARG A CB  
982  C CG  . ARG A 66  ? 0.82820 0.97850 0.75900 0.10760  0.03830  0.02390  66  ARG A CG  
983  C CD  . ARG A 66  ? 0.91040 1.06040 0.82850 0.10400  0.05070  0.02920  66  ARG A CD  
984  N NE  . ARG A 66  ? 0.96970 1.10300 0.86730 0.10630  0.05780  0.04460  66  ARG A NE  
985  C CZ  . ARG A 66  ? 1.02000 1.15620 0.89600 0.11590  0.05720  0.05180  66  ARG A CZ  
986  N NH1 . ARG A 66  ? 0.94740 1.10470 0.81950 0.12150  0.04930  0.04400  66  ARG A NH1 
987  N NH2 . ARG A 66  ? 1.06650 1.17990 0.91930 0.12020  0.06510  0.06730  66  ARG A NH2 
1001 N N   . VAL A 67  ? 0.63210 0.78180 0.56780 0.10060  0.01150  -0.02090 67  VAL A N   
1002 C CA  . VAL A 67  ? 0.61880 0.75090 0.54630 0.10040  0.00980  -0.03450 67  VAL A CA  
1003 C C   . VAL A 67  ? 0.66310 0.78550 0.59880 0.09020  0.00050  -0.03830 67  VAL A C   
1004 O O   . VAL A 67  ? 0.60640 0.71360 0.54810 0.09080  0.00190  -0.04330 67  VAL A O   
1005 C CB  . VAL A 67  ? 0.69570 0.81740 0.58960 0.10320  0.00810  -0.04450 67  VAL A CB  
1006 C CG1 . VAL A 67  ? 0.67030 0.76000 0.54440 0.10350  0.00610  -0.05880 67  VAL A CG1 
1007 C CG2 . VAL A 67  ? 0.70720 0.84010 0.59340 0.11520  0.01980  -0.04100 67  VAL A CG2 
1017 N N   . GLU A 68  ? 0.60950 0.74520 0.54520 0.08110  -0.00890 -0.03490 68  GLU A N   
1018 C CA  . GLU A 68  ? 0.61250 0.74690 0.55690 0.06880  -0.01710 -0.03710 68  GLU A CA  
1019 C C   . GLU A 68  ? 0.62260 0.75710 0.59410 0.07260  -0.01200 -0.03020 68  GLU A C   
1020 O O   . GLU A 68  ? 0.59740 0.71800 0.57370 0.06630  -0.01410 -0.03510 68  GLU A O   
1021 C CB  . GLU A 68  ? 0.61830 0.78310 0.56270 0.05970  -0.02740 -0.03150 68  GLU A CB  
1022 C CG  . GLU A 68  ? 0.64490 0.80780 0.55820 0.04770  -0.03610 -0.04120 68  GLU A CG  
1023 C CD  . GLU A 68  ? 0.65200 0.85900 0.56740 0.03970  -0.04700 -0.03330 68  GLU A CD  
1024 O OE1 . GLU A 68  ? 0.60880 0.84720 0.54950 0.04880  -0.04620 -0.01900 68  GLU A OE1 
1025 O OE2 . GLU A 68  ? 0.67270 0.88330 0.56150 0.02530  -0.05630 -0.04100 68  GLU A OE2 
1032 N N   . ALA A 69  ? 0.58950 0.73420 0.57350 0.08180  -0.00480 -0.01910 69  ALA A N   
1033 C CA  . ALA A 69  ? 0.58340 0.72290 0.58610 0.08350  0.00040  -0.01330 69  ALA A CA  
1034 C C   . ALA A 69  ? 0.61980 0.74330 0.62640 0.08340  0.00480  -0.02050 69  ALA A C   
1035 O O   . ALA A 69  ? 0.59140 0.70660 0.60820 0.08000  0.00350  -0.02230 69  ALA A O   
1036 C CB  . ALA A 69  ? 0.56710 0.70910 0.57060 0.09120  0.00840  -0.00070 69  ALA A CB  
1042 N N   . PHE A 70  ? 0.57370 0.69710 0.57190 0.08880  0.01040  -0.02360 70  PHE A N   
1043 C CA  . PHE A 70  ? 0.62500 0.74440 0.62840 0.09270  0.01490  -0.02820 70  PHE A CA  
1044 C C   . PHE A 70  ? 0.63520 0.73470 0.62820 0.09400  0.00960  -0.03840 70  PHE A C   
1045 O O   . PHE A 70  ? 0.63880 0.73110 0.64010 0.09500  0.00970  -0.03970 70  PHE A O   
1046 C CB  . PHE A 70  ? 0.57920 0.71200 0.57600 0.10040  0.02300  -0.02810 70  PHE A CB  
1047 C CG  . PHE A 70  ? 0.57500 0.71610 0.57850 0.10800  0.02780  -0.03100 70  PHE A CG  
1048 C CD1 . PHE A 70  ? 0.62180 0.77910 0.64450 0.10160  0.03130  -0.02490 70  PHE A CD1 
1049 C CD2 . PHE A 70  ? 0.59010 0.72200 0.57670 0.12230  0.02860  -0.03960 70  PHE A CD2 
1050 C CE1 . PHE A 70  ? 0.60250 0.77820 0.63330 0.10910  0.03440  -0.02610 70  PHE A CE1 
1051 C CE2 . PHE A 70  ? 0.62600 0.77090 0.61800 0.13490  0.03340  -0.04020 70  PHE A CE2 
1052 C CZ  . PHE A 70  ? 0.57600 0.74870 0.59320 0.12820  0.03560  -0.03300 70  PHE A CZ  
1062 N N   . GLU A 71  ? 0.60620 0.69220 0.57570 0.09280  0.00500  -0.04580 71  GLU A N   
1063 C CA  . GLU A 71  ? 0.68360 0.73800 0.63200 0.09170  0.00120  -0.05600 71  GLU A CA  
1064 C C   . GLU A 71  ? 0.64320 0.69060 0.60370 0.07950  -0.00450 -0.05440 71  GLU A C   
1065 O O   . GLU A 71  ? 0.62860 0.64860 0.57680 0.08040  -0.00500 -0.05980 71  GLU A O   
1066 C CB  . GLU A 71  ? 0.68710 0.72330 0.60200 0.08540  -0.00380 -0.06460 71  GLU A CB  
1067 C CG  . GLU A 71  ? 0.81710 0.84980 0.70990 0.10060  0.00320  -0.06890 71  GLU A CG  
1068 C CD  . GLU A 71  ? 0.99510 1.00900 0.87520 0.12130  0.01190  -0.07340 71  GLU A CD  
1069 O OE1 . GLU A 71  ? 1.07080 1.04710 0.93020 0.12200  0.01010  -0.08010 71  GLU A OE1 
1070 O OE2 . GLU A 71  ? 0.94500 0.98370 0.83410 0.13760  0.02110  -0.06920 71  GLU A OE2 
1077 N N   . TYR A 72  ? 0.57630 0.64680 0.55750 0.07060  -0.00770 -0.04620 72  TYR A N   
1078 C CA  . TYR A 72  ? 0.64440 0.71440 0.63710 0.05990  -0.01200 -0.04370 72  TYR A CA  
1079 C C   . TYR A 72  ? 0.56050 0.63300 0.57430 0.06610  -0.00670 -0.03810 72  TYR A C   
1080 O O   . TYR A 72  ? 0.59600 0.65360 0.61030 0.06290  -0.00780 -0.04010 72  TYR A O   
1081 C CB  . TYR A 72  ? 0.60870 0.70740 0.61080 0.05100  -0.01730 -0.03660 72  TYR A CB  
1082 C CG  . TYR A 72  ? 0.61520 0.71960 0.62450 0.03730  -0.02240 -0.03500 72  TYR A CG  
1083 C CD1 . TYR A 72  ? 0.63860 0.72210 0.62740 0.02030  -0.02810 -0.04360 72  TYR A CD1 
1084 C CD2 . TYR A 72  ? 0.63440 0.76220 0.66640 0.04100  -0.02010 -0.02460 72  TYR A CD2 
1085 C CE1 . TYR A 72  ? 0.60060 0.69270 0.59550 0.00430  -0.03200 -0.04120 72  TYR A CE1 
1086 C CE2 . TYR A 72  ? 0.58260 0.72210 0.62220 0.02950  -0.02340 -0.02210 72  TYR A CE2 
1087 C CZ  . TYR A 72  ? 0.59960 0.72450 0.62270 0.00960  -0.02950 -0.03010 72  TYR A CZ  
1088 O OH  . TYR A 72  ? 0.62740 0.76730 0.65780 -0.00540 -0.03210 -0.02670 72  TYR A OH  
1098 N N   . TYR A 73  ? 0.60170 0.68980 0.62850 0.07280  -0.00100 -0.03120 73  TYR A N   
1099 C CA  . TYR A 73  ? 0.54750 0.63640 0.58910 0.07400  0.00340  -0.02620 73  TYR A CA  
1100 C C   . TYR A 73  ? 0.60520 0.69580 0.64850 0.07980  0.00800  -0.02830 73  TYR A C   
1101 O O   . TYR A 73  ? 0.54900 0.63970 0.60150 0.07790  0.00950  -0.02640 73  TYR A O   
1102 C CB  . TYR A 73  ? 0.52670 0.62470 0.57400 0.07440  0.00770  -0.01650 73  TYR A CB  
1103 C CG  . TYR A 73  ? 0.57430 0.68150 0.62310 0.07400  0.00420  -0.01130 73  TYR A CG  
1104 C CD1 . TYR A 73  ? 0.53120 0.63820 0.58770 0.07110  0.00240  -0.00980 73  TYR A CD1 
1105 C CD2 . TYR A 73  ? 0.50110 0.62310 0.54360 0.07770  0.00290  -0.00680 73  TYR A CD2 
1106 C CE1 . TYR A 73  ? 0.50570 0.63280 0.56620 0.07210  -0.00020 -0.00340 73  TYR A CE1 
1107 C CE2 . TYR A 73  ? 0.52930 0.67160 0.57520 0.07950  -0.00090 -0.00030 73  TYR A CE2 
1108 C CZ  . TYR A 73  ? 0.52820 0.67580 0.58430 0.07680  -0.00210 0.00160  73  TYR A CZ  
1109 O OH  . TYR A 73  ? 0.58140 0.76020 0.64350 0.07990  -0.00510 0.00970  73  TYR A OH  
1119 N N   . HIS A 74  ? 0.54350 0.64020 0.57780 0.08700  0.01040  -0.03160 74  HIS A N   
1120 C CA  . HIS A 74  ? 0.60600 0.71820 0.64420 0.09470  0.01570  -0.03160 74  HIS A CA  
1121 C C   . HIS A 74  ? 0.58160 0.71260 0.63320 0.08540  0.02060  -0.02390 74  HIS A C   
1122 O O   . HIS A 74  ? 0.54790 0.69500 0.60880 0.08350  0.02240  -0.02250 74  HIS A O   
1123 C CB  . HIS A 74  ? 0.61260 0.71620 0.64970 0.10230  0.01360  -0.03550 74  HIS A CB  
1124 C CG  . HIS A 74  ? 0.63210 0.70940 0.64490 0.11350  0.01190  -0.04330 74  HIS A CG  
1125 N ND1 . HIS A 74  ? 0.71350 0.77490 0.71490 0.12620  0.01190  -0.04630 74  HIS A ND1 
1126 C CD2 . HIS A 74  ? 0.66620 0.72470 0.65730 0.11330  0.01040  -0.04890 74  HIS A CD2 
1127 C CE1 . HIS A 74  ? 0.73260 0.75920 0.70270 0.13350  0.01160  -0.05360 74  HIS A CE1 
1128 N NE2 . HIS A 74  ? 0.68060 0.70570 0.64410 0.12390  0.01020  -0.05610 74  HIS A NE2 
1136 N N   . THR A 75  ? 0.56730 0.69500 0.61580 0.07870  0.02280  -0.01850 75  THR A N   
1137 C CA  . THR A 75  ? 0.57380 0.70600 0.62370 0.06740  0.02900  -0.01120 75  THR A CA  
1138 C C   . THR A 75  ? 0.58710 0.71640 0.62480 0.06720  0.03340  -0.00550 75  THR A C   
1139 O O   . THR A 75  ? 0.58370 0.70520 0.61480 0.07420  0.02990  -0.00540 75  THR A O   
1140 C CB  . THR A 75  ? 0.57860 0.69030 0.62910 0.05940  0.02820  -0.00830 75  THR A CB  
1141 O OG1 . THR A 75  ? 0.59880 0.70470 0.64110 0.04560  0.03500  -0.00240 75  THR A OG1 
1142 C CG2 . THR A 75  ? 0.60360 0.69800 0.64860 0.06560  0.02580  -0.00580 75  THR A CG2 
1150 N N   . THR A 76  ? 0.57030 0.70840 0.60350 0.05730  0.04100  -0.00000 76  THR A N   
1151 C CA  . THR A 76  ? 0.61870 0.74800 0.63520 0.05540  0.04700  0.00750  76  THR A CA  
1152 C C   . THR A 76  ? 0.65170 0.75370 0.65260 0.04100  0.05370  0.01570  76  THR A C   
1153 O O   . THR A 76  ? 0.68170 0.77440 0.66420 0.03400  0.06160  0.02310  76  THR A O   
1154 C CB  . THR A 76  ? 0.58570 0.74320 0.60100 0.05550  0.05250  0.00790  76  THR A CB  
1155 O OG1 . THR A 76  ? 0.54480 0.72710 0.56960 0.04160  0.05710  0.00900  76  THR A OG1 
1156 C CG2 . THR A 76  ? 0.58750 0.75940 0.60680 0.07270  0.04750  -0.00070 76  THR A CG2 
1164 N N   . ASP A 77  ? 0.60720 0.69070 0.60960 0.03600  0.05170  0.01430  77  ASP A N   
1165 C CA  . ASP A 77  ? 0.64980 0.69390 0.62750 0.02410  0.05870  0.02080  77  ASP A CA  
1166 C C   . ASP A 77  ? 0.69390 0.70820 0.64960 0.03970  0.06250  0.02910  77  ASP A C   
1167 O O   . ASP A 77  ? 0.67170 0.68830 0.63550 0.05770  0.05700  0.02860  77  ASP A O   
1168 C CB  . ASP A 77  ? 0.69010 0.71910 0.67140 0.01970  0.05540  0.01650  77  ASP A CB  
1169 C CG  . ASP A 77  ? 0.77910 0.76010 0.72700 0.00480  0.06370  0.02130  77  ASP A CG  
1170 O OD1 . ASP A 77  ? 0.83720 0.78210 0.75520 0.00960  0.07170  0.02950  77  ASP A OD1 
1171 O OD2 . ASP A 77  ? 0.84950 0.82480 0.79600 -0.01110 0.06230  0.01700  77  ASP A OD2 
1176 N N   . PRO A 78  ? 0.77100 0.75970 0.69740 0.03370  0.07200  0.03800  78  PRO A N   
1177 C CA  . PRO A 78  ? 0.80580 0.77020 0.70940 0.05440  0.07550  0.04780  78  PRO A CA  
1178 C C   . PRO A 78  ? 0.81520 0.75110 0.70840 0.07140  0.07590  0.05110  78  PRO A C   
1179 O O   . PRO A 78  ? 0.82240 0.76550 0.71440 0.09530  0.07370  0.05720  78  PRO A O   
1180 C CB  . PRO A 78  ? 0.81740 0.74560 0.68250 0.04090  0.08790  0.05730  78  PRO A CB  
1181 C CG  . PRO A 78  ? 0.80230 0.75140 0.67720 0.01090  0.08960  0.05190  78  PRO A CG  
1182 C CD  . PRO A 78  ? 0.74800 0.73160 0.65900 0.00710  0.08000  0.04050  78  PRO A CD  
1190 N N   . SER A 79  ? 0.78260 0.69080 0.66740 0.06040  0.07860  0.04760  79  SER A N   
1191 C CA  . SER A 79  ? 0.75400 0.63030 0.62260 0.07820  0.08180  0.05140  79  SER A CA  
1192 C C   . SER A 79  ? 0.74960 0.66130 0.65420 0.08640  0.07180  0.04400  79  SER A C   
1193 O O   . SER A 79  ? 0.76040 0.65390 0.65570 0.10110  0.07470  0.04680  79  SER A O   
1194 C CB  . SER A 79  ? 0.82250 0.63760 0.65090 0.06130  0.09200  0.05180  79  SER A CB  
1195 O OG  . SER A 79  ? 0.88270 0.71450 0.72970 0.03380  0.08660  0.04090  79  SER A OG  
1201 N N   . PHE A 80  ? 0.67450 0.63300 0.61540 0.07850  0.06140  0.03530  80  PHE A N   
1202 C CA  . PHE A 80  ? 0.74400 0.72780 0.71280 0.08200  0.05270  0.02820  80  PHE A CA  
1203 C C   . PHE A 80  ? 0.72680 0.72240 0.69910 0.10440  0.05110  0.03440  80  PHE A C   
1204 O O   . PHE A 80  ? 0.69590 0.68370 0.66800 0.11170  0.05260  0.03530  80  PHE A O   
1205 C CB  . PHE A 80  ? 0.66080 0.68360 0.65760 0.07410  0.04350  0.01920  80  PHE A CB  
1206 C CG  . PHE A 80  ? 0.66120 0.70060 0.67960 0.07480  0.03550  0.01200  80  PHE A CG  
1207 C CD1 . PHE A 80  ? 0.64640 0.68010 0.67020 0.06410  0.03450  0.00630  80  PHE A CD1 
1208 C CD2 . PHE A 80  ? 0.65550 0.71660 0.68580 0.08390  0.02890  0.01150  80  PHE A CD2 
1209 C CE1 . PHE A 80  ? 0.61930 0.66340 0.65850 0.06540  0.02810  0.00080  80  PHE A CE1 
1210 C CE2 . PHE A 80  ? 0.62570 0.69640 0.67050 0.08100  0.02260  0.00560  80  PHE A CE2 
1211 C CZ  . PHE A 80  ? 0.61880 0.67830 0.66720 0.07320  0.02270  0.00060  80  PHE A CZ  
1221 N N   . LEU A 81  ? 0.66050 0.68080 0.63620 0.11530  0.04780  0.03930  81  LEU A N   
1222 C CA  . LEU A 81  ? 0.71760 0.76540 0.70100 0.13420  0.04430  0.04590  81  LEU A CA  
1223 C C   . LEU A 81  ? 0.69420 0.71440 0.65420 0.15480  0.05490  0.05690  81  LEU A C   
1224 O O   . LEU A 81  ? 0.68600 0.72540 0.65650 0.16630  0.05400  0.05960  81  LEU A O   
1225 C CB  . LEU A 81  ? 0.79200 0.86870 0.77550 0.14180  0.03950  0.05090  81  LEU A CB  
1226 C CG  . LEU A 81  ? 0.88170 1.00300 0.88990 0.13210  0.02620  0.04270  81  LEU A CG  
1227 C CD1 . LEU A 81  ? 0.79110 0.94280 0.81690 0.13510  0.02070  0.04370  81  LEU A CD1 
1228 C CD2 . LEU A 81  ? 0.80340 0.91670 0.82070 0.11230  0.02280  0.02890  81  LEU A CD2 
1240 N N   . GLY A 82  ? 0.74920 0.72160 0.67290 0.16000  0.06610  0.06370  82  GLY A N   
1241 C CA  . GLY A 82  ? 0.68680 0.61810 0.57670 0.18230  0.07860  0.07370  82  GLY A CA  
1242 C C   . GLY A 82  ? 0.77220 0.68610 0.66410 0.17670  0.08080  0.06700  82  GLY A C   
1243 O O   . GLY A 82  ? 0.75700 0.67370 0.64370 0.19960  0.08580  0.07340  82  GLY A O   
1247 N N   . ARG A 83  ? 0.74920 0.64970 0.64840 0.14750  0.07750  0.05490  83  ARG A N   
1248 C CA  . ARG A 83  ? 0.78340 0.66640 0.68170 0.14030  0.07890  0.04820  83  ARG A CA  
1249 C C   . ARG A 83  ? 0.70030 0.63580 0.63800 0.14480  0.06970  0.04500  83  ARG A C   
1250 O O   . ARG A 83  ? 0.70830 0.63770 0.64240 0.15440  0.07370  0.04580  83  ARG A O   
1251 C CB  . ARG A 83  ? 0.72580 0.58980 0.62200 0.10780  0.07640  0.03740  83  ARG A CB  
1252 C CG  . ARG A 83  ? 0.86970 0.67740 0.72100 0.09580  0.08660  0.04050  83  ARG A CG  
1253 C CD  . ARG A 83  ? 0.87590 0.67440 0.72550 0.06030  0.08370  0.03070  83  ARG A CD  
1254 N NE  . ARG A 83  ? 0.83880 0.68860 0.72400 0.04510  0.07440  0.02620  83  ARG A NE  
1255 C CZ  . ARG A 83  ? 0.77610 0.67330 0.70120 0.04080  0.06350  0.01850  83  ARG A CZ  
1256 N NH1 . ARG A 83  ? 0.73010 0.63310 0.66760 0.04730  0.05950  0.01450  83  ARG A NH1 
1257 N NH2 . ARG A 83  ? 0.71290 0.64980 0.66190 0.03160  0.05760  0.01540  83  ARG A NH2 
1271 N N   . TYR A 84  ? 0.62090 0.60470 0.59170 0.13690  0.05820  0.04120  84  TYR A N   
1272 C CA  . TYR A 84  ? 0.59280 0.62170 0.59450 0.13700  0.04970  0.03880  84  TYR A CA  
1273 C C   . TYR A 84  ? 0.70730 0.76270 0.70910 0.16220  0.05370  0.05080  84  TYR A C   
1274 O O   . TYR A 84  ? 0.66830 0.74150 0.68080 0.16660  0.05430  0.05190  84  TYR A O   
1275 C CB  . TYR A 84  ? 0.58610 0.64940 0.61120 0.12270  0.03790  0.03210  84  TYR A CB  
1276 C CG  . TYR A 84  ? 0.60200 0.70710 0.65120 0.11820  0.02900  0.03000  84  TYR A CG  
1277 C CD1 . TYR A 84  ? 0.61450 0.72060 0.67220 0.11330  0.02890  0.02720  84  TYR A CD1 
1278 C CD2 . TYR A 84  ? 0.61770 0.75920 0.67710 0.11550  0.02070  0.03050  84  TYR A CD2 
1279 C CE1 . TYR A 84  ? 0.57380 0.71500 0.64920 0.10450  0.02150  0.02580  84  TYR A CE1 
1280 C CE2 . TYR A 84  ? 0.58610 0.76220 0.66180 0.10480  0.01240  0.02810  84  TYR A CE2 
1281 C CZ  . TYR A 84  ? 0.63920 0.81440 0.72270 0.09850  0.01320  0.02610  84  TYR A CZ  
1282 O OH  . TYR A 84  ? 0.61570 0.82230 0.71140 0.08350  0.00570  0.02420  84  TYR A OH  
1292 N N   . MET A 85  ? 0.65770 0.71980 0.64670 0.18060  0.05690  0.06130  85  MET A N   
1293 C CA  . MET A 85  ? 0.62980 0.72840 0.61990 0.20900  0.06040  0.07510  85  MET A CA  
1294 C C   . MET A 85  ? 0.67080 0.73230 0.63270 0.23310  0.07540  0.08220  85  MET A C   
1295 O O   . MET A 85  ? 0.67890 0.77720 0.65140 0.25100  0.07830  0.08960  85  MET A O   
1296 C CB  . MET A 85  ? 0.67930 0.79220 0.65830 0.22570  0.06030  0.08560  85  MET A CB  
1297 C CG  . MET A 85  ? 0.57330 0.73860 0.57990 0.20800  0.04510  0.08090  85  MET A CG  
1298 S SD  . MET A 85  ? 0.66090 0.90690 0.70540 0.20010  0.03340  0.08130  85  MET A SD  
1299 C CE  . MET A 85  ? 0.60410 0.83710 0.66600 0.15930  0.02230  0.06100  85  MET A CE  
1309 N N   . SER A 86  ? 0.70350 0.69190 0.62600 0.23310  0.08580  0.08030  86  SER A N   
1310 C CA  . SER A 86  ? 0.76490 0.70430 0.64970 0.25530  0.10130  0.08550  86  SER A CA  
1311 C C   . SER A 86  ? 0.71770 0.66820 0.62010 0.24520  0.09980  0.07770  86  SER A C   
1312 O O   . SER A 86  ? 0.74190 0.69810 0.63500 0.27080  0.10920  0.08520  86  SER A O   
1313 C CB  . SER A 86  ? 0.80640 0.65830 0.64010 0.24670  0.11130  0.08230  86  SER A CB  
1314 O OG  . SER A 86  ? 0.98890 0.83040 0.80870 0.24790  0.11140  0.08800  86  SER A OG  
1320 N N   . ALA A 87  ? 0.69920 0.65390 0.62510 0.21060  0.08900  0.06370  87  ALA A N   
1321 C CA  . ALA A 87  ? 0.72130 0.68560 0.66250 0.20020  0.08690  0.05680  87  ALA A CA  
1322 C C   . ALA A 87  ? 0.70580 0.74260 0.68400 0.20750  0.08140  0.06240  87  ALA A C   
1323 O O   . ALA A 87  ? 0.68310 0.73140 0.66290 0.21740  0.08720  0.06530  87  ALA A O   
1324 C CB  . ALA A 87  ? 0.66370 0.61810 0.61910 0.16510  0.07640  0.04240  87  ALA A CB  
1330 N N   . LEU A 88  ? 0.69230 0.77930 0.69820 0.20050  0.07060  0.06410  88  LEU A N   
1331 C CA  . LEU A 88  ? 0.64200 0.80040 0.68060 0.19980  0.06410  0.06910  88  LEU A CA  
1332 C C   . LEU A 88  ? 0.63520 0.82440 0.66740 0.23490  0.07550  0.08490  88  LEU A C   
1333 O O   . LEU A 88  ? 0.64650 0.88440 0.69900 0.23540  0.07560  0.08910  88  LEU A O   
1334 C CB  . LEU A 88  ? 0.62640 0.82640 0.68540 0.18640  0.05110  0.06840  88  LEU A CB  
1335 C CG  . LEU A 88  ? 0.63780 0.91340 0.72690 0.17740  0.04230  0.07270  88  LEU A CG  
1336 C CD1 . LEU A 88  ? 0.60520 0.88300 0.70810 0.15360  0.03910  0.06460  88  LEU A CD1 
1337 C CD2 . LEU A 88  ? 0.64940 0.95360 0.74940 0.16070  0.02910  0.06950  88  LEU A CD2 
1349 N N   . ASN A 89  ? 0.69150 0.85320 0.69290 0.26600  0.08610  0.09480  89  ASN A N   
1350 C CA  . ASN A 89  ? 0.73510 0.92360 0.72470 0.30760  0.09910  0.11150  89  ASN A CA  
1351 C C   . ASN A 89  ? 0.67840 0.84540 0.65530 0.31740  0.11100  0.11070  89  ASN A C   
1352 O O   . ASN A 89  ? 0.75920 0.97270 0.74000 0.34700  0.11990  0.12380  89  ASN A O   
1353 C CB  . ASN A 89  ? 0.74890 0.88920 0.69460 0.34130  0.11070  0.12170  89  ASN A CB  
1354 C CG  . ASN A 89  ? 0.85310 1.05610 0.80070 0.38450  0.11660  0.14240  89  ASN A CG  
1355 O OD1 . ASN A 89  ? 0.84350 1.13610 0.83190 0.37810  0.10460  0.14800  89  ASN A OD1 
1356 N ND2 . ASN A 89  ? 0.91890 1.07430 0.81810 0.42750  0.13500  0.15410  89  ASN A ND2 
1363 N N   . HIS A 90  ? 0.69340 0.79610 0.65460 0.29420  0.11130  0.09620  90  HIS A N   
1364 C CA  . HIS A 90  ? 0.73200 0.80960 0.67820 0.29920  0.12130  0.09340  90  HIS A CA  
1365 C C   . HIS A 90  ? 0.66340 0.78590 0.64920 0.26860  0.11070  0.08600  90  HIS A C   
1366 O O   . HIS A 90  ? 0.71330 0.87000 0.70740 0.27950  0.11740  0.09180  90  HIS A O   
1367 C CB  . HIS A 90  ? 0.71410 0.69340 0.61350 0.29050  0.12790  0.08240  90  HIS A CB  
1368 C CG  . HIS A 90  ? 0.78610 0.70210 0.63080 0.32160  0.14300  0.09000  90  HIS A CG  
1369 N ND1 . HIS A 90  ? 0.79580 0.66890 0.62010 0.31180  0.14050  0.08770  90  HIS A ND1 
1370 C CD2 . HIS A 90  ? 0.83990 0.72250 0.64040 0.36330  0.16220  0.10020  90  HIS A CD2 
1371 C CE1 . HIS A 90  ? 0.80400 0.61570 0.57160 0.34380  0.15710  0.09640  90  HIS A CE1 
1372 N NE2 . HIS A 90  ? 0.98090 0.79460 0.73130 0.37740  0.17080  0.10400  90  HIS A NE2 
1380 N N   . THR A 91  ? 0.60940 0.73030 0.61630 0.23180  0.09530  0.07390  91  THR A N   
1381 C CA  . THR A 91  ? 0.63540 0.78220 0.66940 0.20320  0.08630  0.06660  91  THR A CA  
1382 C C   . THR A 91  ? 0.62420 0.85460 0.69240 0.20080  0.08200  0.07580  91  THR A C   
1383 O O   . THR A 91  ? 0.62680 0.88140 0.70950 0.18570  0.08090  0.07480  91  THR A O   
1384 C CB  . THR A 91  ? 0.65150 0.77490 0.69430 0.17060  0.07230  0.05300  91  THR A CB  
1385 O OG1 . THR A 91  ? 0.64140 0.79400 0.69930 0.16600  0.06350  0.05470  91  THR A OG1 
1386 C CG2 . THR A 91  ? 0.68250 0.73510 0.69430 0.16780  0.07590  0.04460  91  THR A CG2 
1394 N N   . LYS A 92  ? 0.61330 0.89060 0.69310 0.21300  0.07920  0.08530  92  LYS A N   
1395 C CA  . LYS A 92  ? 0.64810 1.01410 0.75970 0.20750  0.07430  0.09500  92  LYS A CA  
1396 C C   . LYS A 92  ? 0.63760 1.04380 0.74990 0.23440  0.08870  0.10830  92  LYS A C   
1397 O O   . LYS A 92  ? 0.66630 1.15030 0.80650 0.22360  0.08570  0.11600  92  LYS A O   
1398 C CB  . LYS A 92  ? 0.59370 1.00440 0.71510 0.21560  0.06730  0.10270  92  LYS A CB  
1399 C CG  . LYS A 92  ? 0.70310 1.13460 0.81010 0.26360  0.08010  0.11980  92  LYS A CG  
1400 C CD  . LYS A 92  ? 0.76620 1.23590 0.88020 0.26960  0.07120  0.12650  92  LYS A CD  
1401 C CE  . LYS A 92  ? 0.85220 1.34470 0.94880 0.32220  0.08430  0.14590  92  LYS A CE  
1402 N NZ  . LYS A 92  ? 0.80620 1.29220 0.89110 0.33330  0.07900  0.15000  92  LYS A NZ  
1416 N N   . LYS A 93  ? 0.62010 0.97450 0.69920 0.26760  0.10470  0.11110  93  LYS A N   
1417 C CA  . LYS A 93  ? 0.67440 1.05610 0.74750 0.29620  0.12080  0.12230  93  LYS A CA  
1418 C C   . LYS A 93  ? 0.63340 0.98150 0.70090 0.27660  0.12380  0.11260  93  LYS A C   
1419 O O   . LYS A 93  ? 0.65730 1.04170 0.72750 0.29150  0.13530  0.12130  93  LYS A O   
1420 C CB  . LYS A 93  ? 0.71890 1.05400 0.74840 0.34690  0.13890  0.13080  93  LYS A CB  
1421 C CG  . LYS A 93  ? 0.81590 1.17000 0.84120 0.37180  0.13770  0.14140  93  LYS A CG  
1422 C CD  . LYS A 93  ? 0.91070 1.37400 0.96870 0.37660  0.13180  0.15730  93  LYS A CD  
1423 C CE  . LYS A 93  ? 1.02250 1.48630 1.05460 0.40490  0.13260  0.16970  93  LYS A CE  
1424 N NZ  . LYS A 93  ? 1.13990 1.69360 1.20970 0.38760  0.11630  0.17590  93  LYS A NZ  
1438 N N   . TRP A 94  ? 0.64670 0.93120 0.70610 0.24560  0.11430  0.09610  94  TRP A N   
1439 C CA  . TRP A 94  ? 0.64310 0.89480 0.69490 0.22770  0.11590  0.08740  94  TRP A CA  
1440 C C   . TRP A 94  ? 0.65130 0.96940 0.73660 0.20170  0.11010  0.09090  94  TRP A C   
1441 O O   . TRP A 94  ? 0.65040 1.03200 0.76480 0.18710  0.10110  0.09630  94  TRP A O   
1442 C CB  . TRP A 94  ? 0.61490 0.79640 0.65370 0.20120  0.10520  0.07070  94  TRP A CB  
1443 C CG  . TRP A 94  ? 0.66850 0.77710 0.66820 0.21770  0.11180  0.06580  94  TRP A CG  
1444 C CD1 . TRP A 94  ? 0.70530 0.79040 0.67280 0.25430  0.12720  0.07370  94  TRP A CD1 
1445 C CD2 . TRP A 94  ? 0.57930 0.62830 0.56380 0.19680  0.10370  0.05240  94  TRP A CD2 
1446 N NE1 . TRP A 94  ? 0.74670 0.75360 0.67600 0.25300  0.12910  0.06530  94  TRP A NE1 
1447 C CE2 . TRP A 94  ? 0.58500 0.57520 0.52740 0.21650  0.11430  0.05240  94  TRP A CE2 
1448 C CE3 . TRP A 94  ? 0.59820 0.63890 0.59790 0.16450  0.08920  0.04130  94  TRP A CE3 
1449 C CZ2 . TRP A 94  ? 0.62720 0.55760 0.54590 0.19890  0.11000  0.04150  94  TRP A CZ2 
1450 C CZ3 . TRP A 94  ? 0.57820 0.56670 0.55800 0.15280  0.08520  0.03150  94  TRP A CZ3 
1451 C CH2 . TRP A 94  ? 0.56670 0.50400 0.50820 0.16710  0.09500  0.03160  94  TRP A CH2 
1462 N N   . LYS A 95  ? 0.62520 0.92540 0.70200 0.19340  0.11540  0.08780  95  LYS A N   
1463 C CA  . LYS A 95  ? 0.58810 0.93590 0.68800 0.16470  0.11150  0.09050  95  LYS A CA  
1464 C C   . LYS A 95  ? 0.55920 0.85320 0.65300 0.13010  0.09940  0.07620  95  LYS A C   
1465 O O   . LYS A 95  ? 0.60850 0.83490 0.67770 0.13430  0.09960  0.06630  95  LYS A O   
1466 C CB  . LYS A 95  ? 0.63200 1.00550 0.72530 0.18330  0.12830  0.10010  95  LYS A CB  
1467 C CG  . LYS A 95  ? 0.65130 1.08120 0.74720 0.22560  0.14310  0.11630  95  LYS A CG  
1468 C CD  . LYS A 95  ? 0.68560 1.21540 0.82100 0.21520  0.13610  0.12840  95  LYS A CD  
1469 C CE  . LYS A 95  ? 0.75060 1.34740 0.88970 0.26260  0.15140  0.14700  95  LYS A CE  
1470 N NZ  . LYS A 95  ? 0.82450 1.52960 1.00330 0.25150  0.14280  0.15980  95  LYS A NZ  
1484 N N   . TYR A 96  ? 0.55720 0.88090 0.66960 0.09590  0.08910  0.07570  96  TYR A N   
1485 C CA  . TYR A 96  ? 0.58230 0.85600 0.68580 0.06610  0.07760  0.06380  96  TYR A CA  
1486 C C   . TYR A 96  ? 0.62120 0.91650 0.72760 0.03910  0.07860  0.06800  96  TYR A C   
1487 O O   . TYR A 96  ? 0.63530 0.95470 0.75120 0.00880  0.07020  0.06860  96  TYR A O   
1488 C CB  . TYR A 96  ? 0.58180 0.84900 0.69270 0.05020  0.06340  0.05690  96  TYR A CB  
1489 C CG  . TYR A 96  ? 0.56410 0.81500 0.67200 0.07460  0.06330  0.05450  96  TYR A CG  
1490 C CD1 . TYR A 96  ? 0.53910 0.72760 0.62810 0.08220  0.06200  0.04480  96  TYR A CD1 
1491 C CD2 . TYR A 96  ? 0.51720 0.81770 0.63930 0.08890  0.06450  0.06310  96  TYR A CD2 
1492 C CE1 . TYR A 96  ? 0.54930 0.71980 0.63160 0.10010  0.06270  0.04320  96  TYR A CE1 
1493 C CE2 . TYR A 96  ? 0.53720 0.81660 0.65130 0.11120  0.06550  0.06200  96  TYR A CE2 
1494 C CZ  . TYR A 96  ? 0.53940 0.75090 0.63230 0.11510  0.06500  0.05190  96  TYR A CZ  
1495 O OH  . TYR A 96  ? 0.58540 0.77290 0.66650 0.13300  0.06680  0.05130  96  TYR A OH  
1505 N N   . PRO A 97  ? 0.59160 0.87400 0.68510 0.04700  0.08910  0.07080  97  PRO A N   
1506 C CA  . PRO A 97  ? 0.65980 0.96130 0.75280 0.02080  0.09170  0.07620  97  PRO A CA  
1507 C C   . PRO A 97  ? 0.64890 0.88790 0.72190 -0.00490 0.08170  0.06660  97  PRO A C   
1508 O O   . PRO A 97  ? 0.62690 0.80910 0.68560 0.00370  0.07530  0.05630  97  PRO A O   
1509 C CB  . PRO A 97  ? 0.67930 0.98540 0.76160 0.04500  0.10800  0.08260  97  PRO A CB  
1510 C CG  . PRO A 97  ? 0.68470 0.94090 0.74930 0.07760  0.11080  0.07510  97  PRO A CG  
1511 C CD  . PRO A 97  ? 0.54140 0.78090 0.61320 0.07650  0.09840  0.06760  97  PRO A CD  
1519 N N   . GLN A 98  ? 0.69600 0.94810 0.76580 -0.03680 0.08120  0.07120  98  GLN A N   
1520 C CA  . GLN A 98  ? 0.68950 0.87880 0.73230 -0.05890 0.07460  0.06490  98  GLN A CA  
1521 C C   . GLN A 98  ? 0.64270 0.80500 0.66660 -0.04830 0.08370  0.06740  98  GLN A C   
1522 O O   . GLN A 98  ? 0.65570 0.85410 0.68160 -0.05530 0.09460  0.07750  98  GLN A O   
1523 C CB  . GLN A 98  ? 0.72340 0.92750 0.76130 -0.10080 0.07090  0.06870  98  GLN A CB  
1524 C CG  . GLN A 98  ? 0.73480 0.95710 0.78380 -0.11570 0.06010  0.06440  98  GLN A CG  
1525 C CD  . GLN A 98  ? 0.67330 0.83120 0.70750 -0.10460 0.04960  0.05130  98  GLN A CD  
1526 O OE1 . GLN A 98  ? 0.72090 0.81370 0.72480 -0.11270 0.04600  0.04560  98  GLN A OE1 
1527 N NE2 . GLN A 98  ? 0.62540 0.80270 0.67910 -0.08390 0.04560  0.04770  98  GLN A NE2 
1536 N N   . VAL A 99  ? 0.64790 0.75220 0.65330 -0.03210 0.07930  0.05870  99  VAL A N   
1537 C CA  . VAL A 99  ? 0.66220 0.73600 0.64540 -0.02220 0.08550  0.05960  99  VAL A CA  
1538 C C   . VAL A 99  ? 0.66940 0.68690 0.62500 -0.03800 0.07750  0.05640  99  VAL A C   
1539 O O   . VAL A 99  ? 0.61510 0.59580 0.56350 -0.03200 0.06690  0.04800  99  VAL A O   
1540 C CB  . VAL A 99  ? 0.65190 0.70680 0.63080 0.00820  0.08670  0.05300  99  VAL A CB  
1541 C CG1 . VAL A 99  ? 0.64020 0.66790 0.59330 0.01590  0.09300  0.05390  99  VAL A CG1 
1542 C CG2 . VAL A 99  ? 0.62830 0.72710 0.62650 0.02770  0.09520  0.05640  99  VAL A CG2 
1552 N N   . ASN A 100 ? 0.67280 0.68430 0.61060 -0.05660 0.08370  0.06430  100 ASN A N   
1553 C CA  . ASN A 100 ? 0.73380 0.68590 0.63700 -0.06970 0.07850  0.06380  100 ASN A CA  
1554 C C   . ASN A 100 ? 0.73070 0.65450 0.62750 -0.08280 0.06770  0.05770  100 ASN A C   
1555 O O   . ASN A 100 ? 0.73970 0.60980 0.61220 -0.07450 0.06030  0.05270  100 ASN A O   
1556 C CB  . ASN A 100 ? 0.76080 0.67250 0.64430 -0.04550 0.07530  0.05960  100 ASN A CB  
1557 C CG  . ASN A 100 ? 0.80500 0.66260 0.64860 -0.05410 0.07400  0.06370  100 ASN A CG  
1558 O OD1 . ASN A 100 ? 0.80490 0.65710 0.63170 -0.07760 0.08110  0.07220  100 ASN A OD1 
1559 N ND2 . ASN A 100 ? 0.90630 0.72510 0.73260 -0.03500 0.06510  0.05870  100 ASN A ND2 
1566 N N   . GLY A 101 ? 0.71900 0.68150 0.63570 -0.10190 0.06710  0.05850  101 GLY A N   
1567 C CA  . GLY A 101 ? 0.67670 0.61240 0.58290 -0.11760 0.05780  0.05230  101 GLY A CA  
1568 C C   . GLY A 101 ? 0.71860 0.65470 0.64270 -0.09490 0.04900  0.04250  101 GLY A C   
1569 O O   . GLY A 101 ? 0.69980 0.61670 0.61560 -0.10580 0.04190  0.03680  101 GLY A O   
1573 N N   . LEU A 102 ? 0.68650 0.64020 0.63030 -0.06570 0.04990  0.04020  102 LEU A N   
1574 C CA  . LEU A 102 ? 0.65330 0.60860 0.61280 -0.04610 0.04270  0.03180  102 LEU A CA  
1575 C C   . LEU A 102 ? 0.65460 0.66690 0.64700 -0.03760 0.04670  0.03380  102 LEU A C   
1576 O O   . LEU A 102 ? 0.64400 0.68930 0.64580 -0.03270 0.05620  0.04080  102 LEU A O   
1577 C CB  . LEU A 102 ? 0.70940 0.63540 0.65940 -0.02170 0.03980  0.02730  102 LEU A CB  
1578 C CG  . LEU A 102 ? 0.73900 0.61260 0.65550 -0.02070 0.03600  0.02710  102 LEU A CG  
1579 C CD1 . LEU A 102 ? 0.77540 0.63990 0.68740 0.00150  0.03350  0.02500  102 LEU A CD1 
1580 C CD2 . LEU A 102 ? 0.75880 0.60160 0.66180 -0.02320 0.02860  0.02190  102 LEU A CD2 
1592 N N   . THR A 103 ? 0.62270 0.64510 0.62920 -0.03290 0.04040  0.02850  103 THR A N   
1593 C CA  . THR A 103 ? 0.55350 0.62240 0.58610 -0.01930 0.04380  0.03080  103 THR A CA  
1594 C C   . THR A 103 ? 0.60150 0.65510 0.63280 0.00720  0.04690  0.02760  103 THR A C   
1595 O O   . THR A 103 ? 0.61360 0.63490 0.63710 0.01440  0.04030  0.02010  103 THR A O   
1596 C CB  . THR A 103 ? 0.63900 0.72040 0.68270 -0.02460 0.03580  0.02670  103 THR A CB  
1597 O OG1 . THR A 103 ? 0.59950 0.68680 0.63620 -0.05440 0.03190  0.02790  103 THR A OG1 
1598 C CG2 . THR A 103 ? 0.56460 0.69530 0.63210 -0.00860 0.04000  0.03150  103 THR A CG2 
1606 N N   . SER A 104 ? 0.56860 0.64550 0.60420 0.02100  0.05750  0.03350  104 SER A N   
1607 C CA  . SER A 104 ? 0.58350 0.64070 0.60970 0.04350  0.06220  0.03030  104 SER A CA  
1608 C C   . SER A 104 ? 0.58530 0.67010 0.62330 0.06130  0.06800  0.03380  104 SER A C   
1609 O O   . SER A 104 ? 0.59020 0.71190 0.64720 0.05680  0.06550  0.03770  104 SER A O   
1610 C CB  . SER A 104 ? 0.60870 0.65580 0.61780 0.04910  0.07160  0.03360  104 SER A CB  
1611 O OG  . SER A 104 ? 0.60950 0.62350 0.59970 0.06470  0.07380  0.02770  104 SER A OG  
1617 N N   . ILE A 105 ? 0.57890 0.64220 0.60070 0.08170  0.07580  0.03250  105 ILE A N   
1618 C CA  . ILE A 105 ? 0.57820 0.65570 0.60020 0.10450  0.08440  0.03710  105 ILE A CA  
1619 C C   . ILE A 105 ? 0.63160 0.69660 0.63000 0.12600  0.09970  0.04100  105 ILE A C   
1620 O O   . ILE A 105 ? 0.65910 0.67780 0.63080 0.12570  0.10090  0.03400  105 ILE A O   
1621 C CB  . ILE A 105 ? 0.56340 0.60800 0.57700 0.10890  0.07890  0.02990  105 ILE A CB  
1622 C CG1 . ILE A 105 ? 0.50600 0.54930 0.53480 0.08800  0.06400  0.02330  105 ILE A CG1 
1623 C CG2 . ILE A 105 ? 0.59580 0.66000 0.61170 0.13080  0.08640  0.03710  105 ILE A CG2 
1624 C CD1 . ILE A 105 ? 0.53180 0.54730 0.55300 0.08970  0.05910  0.01660  105 ILE A CD1 
1636 N N   . LYS A 106 ? 0.63560 0.74410 0.64150 0.14540  0.11170  0.05240  106 LYS A N   
1637 C CA  . LYS A 106 ? 0.67310 0.76620 0.65080 0.17410  0.12900  0.05670  106 LYS A CA  
1638 C C   . LYS A 106 ? 0.75150 0.78170 0.69410 0.19050  0.13250  0.04970  106 LYS A C   
1639 O O   . LYS A 106 ? 0.74660 0.77170 0.69500 0.19100  0.12650  0.04820  106 LYS A O   
1640 C CB  . LYS A 106 ? 0.67260 0.83390 0.66720 0.19710  0.14150  0.07230  106 LYS A CB  
1641 C CG  . LYS A 106 ? 0.75140 0.90560 0.71690 0.22990  0.16210  0.07870  106 LYS A CG  
1642 C CD  . LYS A 106 ? 0.86260 1.07550 0.83700 0.26630  0.17570  0.09450  106 LYS A CD  
1643 C CE  . LYS A 106 ? 0.99940 1.29620 1.00000 0.26760  0.18450  0.10840  106 LYS A CE  
1644 N NZ  . LYS A 106 ? 0.94070 1.31470 0.95800 0.30200  0.19550  0.12590  106 LYS A NZ  
1658 N N   . TRP A 107 ? 0.77210 0.75080 0.67360 0.20160  0.14260  0.04510  107 TRP A N   
1659 C CA  . TRP A 107 ? 0.88400 0.79170 0.74270 0.20860  0.14540  0.03660  107 TRP A CA  
1660 C C   . TRP A 107 ? 0.88030 0.78790 0.73050 0.23650  0.15430  0.04420  107 TRP A C   
1661 O O   . TRP A 107 ? 0.84750 0.80140 0.70850 0.26440  0.16560  0.05730  107 TRP A O   
1662 C CB  . TRP A 107 ? 0.96250 0.81520 0.77030 0.21940  0.15800  0.03170  107 TRP A CB  
1663 C CG  . TRP A 107 ? 1.03560 0.81590 0.78730 0.23810  0.16920  0.02770  107 TRP A CG  
1664 C CD1 . TRP A 107 ? 1.09860 0.86570 0.82120 0.27800  0.18840  0.03680  107 TRP A CD1 
1665 C CD2 . TRP A 107 ? 1.11550 0.82530 0.82910 0.21680  0.16270  0.01440  107 TRP A CD2 
1666 N NE1 . TRP A 107 ? 1.18290 0.86410 0.84600 0.28270  0.19480  0.02940  107 TRP A NE1 
1667 C CE2 . TRP A 107 ? 1.18200 0.82870 0.83950 0.24210  0.17890  0.01530  107 TRP A CE2 
1668 C CE3 . TRP A 107 ? 1.15780 0.85420 0.87750 0.17900  0.14510  0.00280  107 TRP A CE3 
1669 C CZ2 . TRP A 107 ? 1.26890 0.83550 0.87410 0.22450  0.17770  0.00400  107 TRP A CZ2 
1670 C CZ3 . TRP A 107 ? 1.17400 0.80400 0.84840 0.16260  0.14320  -0.00770 107 TRP A CZ3 
1671 C CH2 . TRP A 107 ? 1.13600 0.69970 0.75270 0.18230  0.15920  -0.00750 107 TRP A CH2 
1682 N N   . ALA A 108 ? 0.92540 0.78310 0.75440 0.22920  0.14950  0.03700  108 ALA A N   
1683 C CA  . ALA A 108 ? 0.89690 0.73220 0.70200 0.25630  0.15950  0.04330  108 ALA A CA  
1684 C C   . ALA A 108 ? 0.97510 0.74850 0.75400 0.23580  0.15230  0.03300  108 ALA A C   
1685 O O   . ALA A 108 ? 1.01870 0.80330 0.82380 0.20250  0.13560  0.02480  108 ALA A O   
1686 C CB  . ALA A 108 ? 0.87290 0.78510 0.72400 0.26880  0.15640  0.05610  108 ALA A CB  
1692 N N   . ASP A 109 ? 1.01090 0.71790 0.73460 0.25570  0.16590  0.03400  109 ASP A N   
1693 C CA  . ASP A 109 ? 1.14130 0.79240 0.83710 0.23740  0.16160  0.02730  109 ASP A CA  
1694 C C   . ASP A 109 ? 1.03560 0.68100 0.74470 0.19110  0.14410  0.01330  109 ASP A C   
1695 O O   . ASP A 109 ? 0.95460 0.62050 0.69140 0.16920  0.13120  0.01080  109 ASP A O   
1696 C CB  . ASP A 109 ? 1.10230 0.79030 0.82640 0.24770  0.15800  0.03670  109 ASP A CB  
1697 C CG  . ASP A 109 ? 1.19070 0.92260 0.92420 0.29240  0.17020  0.05310  109 ASP A CG  
1698 O OD1 . ASP A 109 ? 1.33130 1.01540 1.01260 0.32770  0.18930  0.05920  109 ASP A OD1 
1699 O OD2 . ASP A 109 ? 1.11830 0.93290 0.90850 0.29240  0.16090  0.06010  109 ASP A OD2 
1704 N N   . ASN A 110 ? 1.06490 0.68560 0.75310 0.17830  0.14400  0.00490  110 ASN A N   
1705 C CA  . ASN A 110 ? 1.01710 0.63310 0.71120 0.13770  0.12820  -0.00720 110 ASN A CA  
1706 C C   . ASN A 110 ? 0.85360 0.54240 0.61430 0.12100  0.11050  -0.00640 110 ASN A C   
1707 O O   . ASN A 110 ? 0.84090 0.53440 0.61280 0.09410  0.09800  -0.01250 110 ASN A O   
1708 C CB  . ASN A 110 ? 1.08960 0.64040 0.73630 0.11520  0.12840  -0.01490 110 ASN A CB  
1709 C CG  . ASN A 110 ? 1.29530 0.75790 0.86380 0.13210  0.14770  -0.01590 110 ASN A CG  
1710 O OD1 . ASN A 110 ? 1.40260 0.85670 0.95440 0.16790  0.16250  -0.00940 110 ASN A OD1 
1711 N ND2 . ASN A 110 ? 1.28350 0.67860 0.79990 0.10610  0.14850  -0.02370 110 ASN A ND2 
1718 N N   . ASN A 111 ? 0.80920 0.55510 0.61140 0.13660  0.11000  0.00160  111 ASN A N   
1719 C CA  . ASN A 111 ? 0.72410 0.52900 0.58050 0.12260  0.09510  0.00250  111 ASN A CA  
1720 C C   . ASN A 111 ? 0.72030 0.54350 0.59270 0.10510  0.08510  -0.00250 111 ASN A C   
1721 O O   . ASN A 111 ? 0.67600 0.54150 0.58640 0.09720  0.07510  -0.00100 111 ASN A O   
1722 C CB  . ASN A 111 ? 0.71080 0.56720 0.59980 0.14290  0.09870  0.01370  111 ASN A CB  
1723 C CG  . ASN A 111 ? 0.75290 0.63490 0.64730 0.15700  0.10680  0.01990  111 ASN A CG  
1724 O OD1 . ASN A 111 ? 0.81130 0.66650 0.68150 0.15560  0.11140  0.01590  111 ASN A OD1 
1725 N ND2 . ASN A 111 ? 0.73090 0.66880 0.65620 0.16900  0.10860  0.03010  111 ASN A ND2 
1732 N N   . SER A 112 ? 0.69060 0.47850 0.52980 0.09920  0.08780  -0.00830 112 SER A N   
1733 C CA  . SER A 112 ? 0.70760 0.51270 0.55820 0.08670  0.07930  -0.01110 112 SER A CA  
1734 C C   . SER A 112 ? 0.68450 0.51420 0.56230 0.06620  0.06240  -0.01520 112 SER A C   
1735 O O   . SER A 112 ? 0.67470 0.53370 0.57710 0.06290  0.05500  -0.01310 112 SER A O   
1736 C CB  . SER A 112 ? 0.76810 0.52850 0.57290 0.08210  0.08400  -0.01760 112 SER A CB  
1737 O OG  . SER A 112 ? 0.84750 0.57930 0.62930 0.05970  0.07620  -0.02660 112 SER A OG  
1743 N N   . TYR A 113 ? 0.71140 0.52840 0.58190 0.05320  0.05720  -0.02020 113 TYR A N   
1744 C CA  . TYR A 113 ? 0.67410 0.52090 0.57020 0.03780  0.04270  -0.02290 113 TYR A CA  
1745 C C   . TYR A 113 ? 0.62930 0.51310 0.56410 0.04600  0.03890  -0.01770 113 TYR A C   
1746 O O   . TYR A 113 ? 0.56390 0.47160 0.51830 0.04150  0.02910  -0.01810 113 TYR A O   
1747 C CB  . TYR A 113 ? 0.71650 0.54890 0.59760 0.02080  0.03970  -0.02790 113 TYR A CB  
1748 C CG  . TYR A 113 ? 0.70550 0.53350 0.59150 0.02710  0.04540  -0.02460 113 TYR A CG  
1749 C CD1 . TYR A 113 ? 0.67210 0.53550 0.59070 0.02500  0.03800  -0.02300 113 TYR A CD1 
1750 C CD2 . TYR A 113 ? 0.71060 0.49570 0.56360 0.03740  0.05880  -0.02280 113 TYR A CD2 
1751 C CE1 . TYR A 113 ? 0.66150 0.52120 0.58230 0.03050  0.04300  -0.01960 113 TYR A CE1 
1752 C CE2 . TYR A 113 ? 0.72590 0.50580 0.57990 0.04530  0.06410  -0.01840 113 TYR A CE2 
1753 C CZ  . TYR A 113 ? 0.71230 0.53130 0.60150 0.04050  0.05560  -0.01690 113 TYR A CZ  
1754 O OH  . TYR A 113 ? 0.70180 0.51610 0.59020 0.04840  0.06060  -0.01210 113 TYR A OH  
1764 N N   . LEU A 114 ? 0.64530 0.53260 0.58730 0.05890  0.04680  -0.01260 114 LEU A N   
1765 C CA  . LEU A 114 ? 0.60370 0.52520 0.57790 0.06310  0.04270  -0.00840 114 LEU A CA  
1766 C C   . LEU A 114 ? 0.60500 0.54350 0.59070 0.06430  0.04170  -0.00500 114 LEU A C   
1767 O O   . LEU A 114 ? 0.54810 0.50440 0.55160 0.05900  0.03430  -0.00480 114 LEU A O   
1768 C CB  . LEU A 114 ? 0.58270 0.50980 0.55990 0.07630  0.05060  -0.00270 114 LEU A CB  
1769 C CG  . LEU A 114 ? 0.65500 0.56430 0.62060 0.07460  0.05180  -0.00440 114 LEU A CG  
1770 C CD1 . LEU A 114 ? 0.62940 0.53500 0.58660 0.09420  0.06260  0.00320  114 LEU A CD1 
1771 C CD2 . LEU A 114 ? 0.62000 0.55220 0.60850 0.06410  0.04120  -0.00720 114 LEU A CD2 
1783 N N   . ALA A 115 ? 0.58300 0.51220 0.55390 0.07100  0.05030  -0.00220 115 ALA A N   
1784 C CA  . ALA A 115 ? 0.56210 0.50670 0.54070 0.06930  0.05090  0.00210  115 ALA A CA  
1785 C C   . ALA A 115 ? 0.56860 0.50640 0.54570 0.05820  0.04040  -0.00170 115 ALA A C   
1786 O O   . ALA A 115 ? 0.57100 0.51980 0.55960 0.05270  0.03560  0.00050  115 ALA A O   
1787 C CB  . ALA A 115 ? 0.63770 0.57290 0.59680 0.08000  0.06330  0.00570  115 ALA A CB  
1793 N N   . THR A 116 ? 0.54540 0.46350 0.50400 0.05470  0.03700  -0.00700 116 THR A N   
1794 C CA  . THR A 116 ? 0.62710 0.54490 0.58310 0.04880  0.02700  -0.00870 116 THR A CA  
1795 C C   . THR A 116 ? 0.61370 0.54590 0.58680 0.04700  0.01750  -0.01050 116 THR A C   
1796 O O   . THR A 116 ? 0.61820 0.55240 0.59210 0.04830  0.01130  -0.00900 116 THR A O   
1797 C CB  . THR A 116 ? 0.62910 0.53120 0.56080 0.04380  0.02450  -0.01350 116 THR A CB  
1798 O OG1 . THR A 116 ? 0.72140 0.63290 0.65290 0.04110  0.01350  -0.01370 116 THR A OG1 
1799 C CG2 . THR A 116 ? 0.62280 0.51640 0.54650 0.03730  0.02450  -0.01910 116 THR A CG2 
1807 N N   . ALA A 117 ? 0.61200 0.55110 0.59470 0.04610  0.01740  -0.01300 117 ALA A N   
1808 C CA  . ALA A 117 ? 0.57110 0.52560 0.56970 0.04670  0.01040  -0.01410 117 ALA A CA  
1809 C C   . ALA A 117 ? 0.55280 0.51000 0.56080 0.04920  0.01100  -0.01090 117 ALA A C   
1810 O O   . ALA A 117 ? 0.57900 0.53460 0.58650 0.05160  0.00550  -0.01120 117 ALA A O   
1811 C CB  . ALA A 117 ? 0.61470 0.57460 0.61910 0.04420  0.01200  -0.01650 117 ALA A CB  
1817 N N   . LEU A 118 ? 0.55140 0.51240 0.56440 0.04860  0.01800  -0.00750 118 LEU A N   
1818 C CA  . LEU A 118 ? 0.57540 0.54320 0.59540 0.04420  0.01790  -0.00460 118 LEU A CA  
1819 C C   . LEU A 118 ? 0.57230 0.52500 0.57910 0.03940  0.01710  -0.00210 118 LEU A C   
1820 O O   . LEU A 118 ? 0.58280 0.52470 0.58370 0.03420  0.01350  -0.00230 118 LEU A O   
1821 C CB  . LEU A 118 ? 0.56770 0.55570 0.59770 0.04460  0.02540  0.00020  118 LEU A CB  
1822 C CG  . LEU A 118 ? 0.60040 0.60460 0.63660 0.03380  0.02580  0.00460  118 LEU A CG  
1823 C CD1 . LEU A 118 ? 0.63120 0.63050 0.66820 0.02600  0.01800  0.00040  118 LEU A CD1 
1824 C CD2 . LEU A 118 ? 0.60770 0.64620 0.65700 0.03790  0.03310  0.01130  118 LEU A CD2 
1836 N N   . LEU A 119 ? 0.57880 0.52460 0.57490 0.04080  0.02120  0.00030  119 LEU A N   
1837 C CA  . LEU A 119 ? 0.60890 0.53790 0.58890 0.03640  0.02130  0.00390  119 LEU A CA  
1838 C C   . LEU A 119 ? 0.58660 0.49630 0.55350 0.04230  0.01300  0.00170  119 LEU A C   
1839 O O   . LEU A 119 ? 0.63650 0.52400 0.58680 0.03980  0.01200  0.00450  119 LEU A O   
1840 C CB  . LEU A 119 ? 0.63980 0.56630 0.60910 0.03860  0.02780  0.00680  119 LEU A CB  
1841 C CG  . LEU A 119 ? 0.62670 0.57320 0.60390 0.03790  0.03870  0.01150  119 LEU A CG  
1842 C CD1 . LEU A 119 ? 0.64650 0.58510 0.60890 0.04660  0.04550  0.01120  119 LEU A CD1 
1843 C CD2 . LEU A 119 ? 0.66660 0.62170 0.64350 0.02520  0.04290  0.01860  119 LEU A CD2 
1855 N N   . THR A 120 ? 0.60450 0.52260 0.57540 0.05050  0.00770  -0.00240 120 THR A N   
1856 C CA  . THR A 120 ? 0.58490 0.49740 0.54630 0.06080  0.00010  -0.00280 120 THR A CA  
1857 C C   . THR A 120 ? 0.63790 0.54060 0.59840 0.06450  -0.00160 -0.00390 120 THR A C   
1858 O O   . THR A 120 ? 0.67460 0.55410 0.61440 0.07360  -0.00360 -0.00150 120 THR A O   
1859 C CB  . THR A 120 ? 0.64120 0.57750 0.61100 0.06440  -0.00520 -0.00640 120 THR A CB  
1860 O OG1 . THR A 120 ? 0.63680 0.57320 0.59800 0.05900  -0.00380 -0.00660 120 THR A OG1 
1861 C CG2 . THR A 120 ? 0.62210 0.56710 0.58620 0.07840  -0.01280 -0.00500 120 THR A CG2 
1869 N N   . LEU A 121 ? 0.62770 0.54360 0.60510 0.05910  -0.00030 -0.00730 121 LEU A N   
1870 C CA  . LEU A 121 ? 0.60820 0.51280 0.58090 0.06120  -0.00190 -0.00960 121 LEU A CA  
1871 C C   . LEU A 121 ? 0.67600 0.54430 0.62350 0.05360  0.00030  -0.00720 121 LEU A C   
1872 O O   . LEU A 121 ? 0.71310 0.55150 0.63720 0.06140  -0.00110 -0.00830 121 LEU A O   
1873 C CB  . LEU A 121 ? 0.62510 0.55030 0.61810 0.05360  -0.00050 -0.01270 121 LEU A CB  
1874 C CG  . LEU A 121 ? 0.60030 0.55170 0.61090 0.05970  -0.00200 -0.01540 121 LEU A CG  
1875 C CD1 . LEU A 121 ? 0.65980 0.62600 0.68510 0.05320  0.00050  -0.01650 121 LEU A CD1 
1876 C CD2 . LEU A 121 ? 0.63200 0.58630 0.63800 0.07330  -0.00630 -0.01740 121 LEU A CD2 
1888 N N   . GLN A 122 ? 0.66740 0.53560 0.61500 0.03820  0.00480  -0.00350 122 GLN A N   
1889 C CA  . GLN A 122 ? 0.69230 0.52820 0.61450 0.02330  0.00760  -0.00050 122 GLN A CA  
1890 C C   . GLN A 122 ? 0.78240 0.57860 0.67160 0.03240  0.00780  0.00370  122 GLN A C   
1891 O O   . GLN A 122 ? 0.79210 0.55370 0.65350 0.01790  0.01140  0.00730  122 GLN A O   
1892 C CB  . GLN A 122 ? 0.73030 0.59060 0.66620 0.00400  0.01320  0.00400  122 GLN A CB  
1893 C CG  . GLN A 122 ? 0.69870 0.59630 0.66070 -0.00500 0.01330  0.00210  122 GLN A CG  
1894 C CD  . GLN A 122 ? 0.63090 0.56770 0.61280 -0.01180 0.01990  0.00820  122 GLN A CD  
1895 O OE1 . GLN A 122 ? 0.63880 0.58660 0.61800 -0.03140 0.02340  0.01320  122 GLN A OE1 
1896 N NE2 . GLN A 122 ? 0.61360 0.57120 0.61230 0.00400  0.02240  0.00820  122 GLN A NE2 
1905 N N   . GLN A 123 ? 0.71180 0.51310 0.60060 0.05440  0.00420  0.00430  123 GLN A N   
1906 C CA  . GLN A 123 ? 0.79800 0.56620 0.65450 0.06800  0.00380  0.00980  123 GLN A CA  
1907 C C   . GLN A 123 ? 0.86020 0.61990 0.70320 0.09560  -0.00070 0.00930  123 GLN A C   
1908 O O   . GLN A 123 ? 0.88340 0.61850 0.69760 0.11350  -0.00130 0.01530  123 GLN A O   
1909 C CB  . GLN A 123 ? 0.74930 0.53900 0.61380 0.07010  0.00360  0.01370  123 GLN A CB  
1910 C CG  . GLN A 123 ? 0.71710 0.51060 0.58610 0.04880  0.01050  0.01660  123 GLN A CG  
1911 C CD  . GLN A 123 ? 0.71630 0.52790 0.58940 0.05270  0.01110  0.01890  123 GLN A CD  
1912 O OE1 . GLN A 123 ? 0.75280 0.54480 0.60130 0.06020  0.01050  0.02420  123 GLN A OE1 
1913 N NE2 . GLN A 123 ? 0.69710 0.54200 0.59610 0.04860  0.01260  0.01490  123 GLN A NE2 
1922 N N   . ILE A 124 ? 0.79510 0.57730 0.65700 0.10200  -0.00320 0.00350  124 ILE A N   
1923 C CA  . ILE A 124 ? 0.86150 0.64440 0.71290 0.13050  -0.00600 0.00370  124 ILE A CA  
1924 C C   . ILE A 124 ? 0.88170 0.63690 0.71890 0.13030  -0.00330 -0.00180 124 ILE A C   
1925 O O   . ILE A 124 ? 0.89610 0.65490 0.74710 0.10710  -0.00210 -0.00700 124 ILE A O   
1926 C CB  . ILE A 124 ? 0.77610 0.62230 0.66360 0.13960  -0.01160 0.00260  124 ILE A CB  
1927 C CG1 . ILE A 124 ? 0.74760 0.62420 0.66930 0.11970  -0.01120 -0.00400 124 ILE A CG1 
1928 C CG2 . ILE A 124 ? 0.71660 0.58460 0.60890 0.13950  -0.01530 0.00730  124 ILE A CG2 
1929 C CD1 . ILE A 124 ? 0.71500 0.64530 0.66550 0.12360  -0.01550 -0.00560 124 ILE A CD1 
1941 N N   . GLU A 125 ? 0.92890 0.65680 0.73530 0.15830  -0.00200 -0.00040 125 GLU A N   
1942 C CA  . GLU A 125 ? 0.98510 0.68320 0.77140 0.16270  0.00120  -0.00650 125 GLU A CA  
1943 C C   . GLU A 125 ? 0.90400 0.66230 0.73160 0.16760  -0.00160 -0.01110 125 GLU A C   
1944 O O   . GLU A 125 ? 0.85160 0.65540 0.69770 0.18990  -0.00420 -0.00750 125 GLU A O   
1945 C CB  . GLU A 125 ? 1.05230 0.69520 0.78440 0.19660  0.00570  -0.00270 125 GLU A CB  
1946 C CG  . GLU A 125 ? 1.24980 0.82900 0.93820 0.19440  0.01120  -0.00990 125 GLU A CG  
1947 C CD  . GLU A 125 ? 1.50080 0.99380 1.11630 0.21860  0.01830  -0.00550 125 GLU A CD  
1948 O OE1 . GLU A 125 ? 1.63710 1.05450 1.20420 0.19630  0.02270  -0.00980 125 GLU A OE1 
1949 O OE2 . GLU A 125 ? 1.50810 1.00850 1.11150 0.25960  0.01950  0.00280  125 GLU A OE2 
1956 N N   . LEU A 126 ? 0.88260 0.64470 0.72400 0.14540  -0.00130 -0.01810 126 LEU A N   
1957 C CA  . LEU A 126 ? 0.84700 0.66090 0.72400 0.14710  -0.00310 -0.02190 126 LEU A CA  
1958 C C   . LEU A 126 ? 0.85250 0.64890 0.72440 0.12840  -0.00190 -0.02910 126 LEU A C   
1959 O O   . LEU A 126 ? 0.88610 0.66750 0.75640 0.10140  -0.00230 -0.03040 126 LEU A O   
1960 C CB  . LEU A 126 ? 0.71500 0.58490 0.63650 0.13370  -0.00670 -0.01970 126 LEU A CB  
1961 C CG  . LEU A 126 ? 0.72400 0.64640 0.67750 0.13710  -0.00800 -0.02150 126 LEU A CG  
1962 C CD1 . LEU A 126 ? 0.70900 0.66400 0.66500 0.16270  -0.00940 -0.01710 126 LEU A CD1 
1963 C CD2 . LEU A 126 ? 0.71060 0.66450 0.69530 0.11530  -0.00940 -0.02150 126 LEU A CD2 
1975 N N   . LYS A 127 ? 0.85950 0.66320 0.72880 0.14260  -0.00040 -0.03330 127 LYS A N   
1976 C CA  . LYS A 127 ? 0.83510 0.62650 0.69800 0.12690  0.00000  -0.04050 127 LYS A CA  
1977 C C   . LYS A 127 ? 0.70420 0.55310 0.60590 0.12900  -0.00100 -0.04140 127 LYS A C   
1978 O O   . LYS A 127 ? 0.70800 0.58410 0.61760 0.15240  0.00090  -0.03950 127 LYS A O   
1979 C CB  . LYS A 127 ? 0.87670 0.60700 0.68560 0.14170  0.00440  -0.04580 127 LYS A CB  
1980 C CG  . LYS A 127 ? 1.11510 0.77610 0.87360 0.14420  0.00730  -0.04390 127 LYS A CG  
1981 C CD  . LYS A 127 ? 1.26480 0.88350 0.99940 0.10520  0.00580  -0.04840 127 LYS A CD  
1982 C CE  . LYS A 127 ? 1.34260 0.89160 1.02680 0.10100  0.00920  -0.04510 127 LYS A CE  
1983 N NZ  . LYS A 127 ? 1.31910 0.87750 1.00920 0.12870  0.01070  -0.03560 127 LYS A NZ  
1997 N N   . PHE A 128 ? 0.72770 0.59730 0.65180 0.10520  -0.00340 -0.04300 128 PHE A N   
1998 C CA  . PHE A 128 ? 0.66090 0.57700 0.61630 0.10520  -0.00350 -0.04290 128 PHE A CA  
1999 C C   . PHE A 128 ? 0.70300 0.60850 0.64030 0.11270  -0.00160 -0.04870 128 PHE A C   
2000 O O   . PHE A 128 ? 0.68740 0.54850 0.58940 0.10800  -0.00150 -0.05440 128 PHE A O   
2001 C CB  . PHE A 128 ? 0.64150 0.58060 0.62240 0.08270  -0.00560 -0.04060 128 PHE A CB  
2002 C CG  . PHE A 128 ? 0.65020 0.60420 0.64940 0.07830  -0.00580 -0.03510 128 PHE A CG  
2003 C CD1 . PHE A 128 ? 0.63970 0.62200 0.65700 0.08650  -0.00510 -0.03210 128 PHE A CD1 
2004 C CD2 . PHE A 128 ? 0.66710 0.60770 0.66290 0.06400  -0.00630 -0.03290 128 PHE A CD2 
2005 C CE1 . PHE A 128 ? 0.61290 0.60320 0.64050 0.08090  -0.00530 -0.02830 128 PHE A CE1 
2006 C CE2 . PHE A 128 ? 0.59200 0.54370 0.60060 0.06180  -0.00540 -0.02830 128 PHE A CE2 
2007 C CZ  . PHE A 128 ? 0.58220 0.55530 0.60470 0.07060  -0.00510 -0.02660 128 PHE A CZ  
2017 N N   . ASN A 129 ? 0.66680 0.61150 0.62480 0.12210  0.00040  -0.04760 129 ASN A N   
2018 C CA  . ASN A 129 ? 0.67160 0.61250 0.61410 0.13140  0.00330  -0.05250 129 ASN A CA  
2019 C C   . ASN A 129 ? 0.66870 0.62220 0.62210 0.11120  0.00070  -0.05430 129 ASN A C   
2020 O O   . ASN A 129 ? 0.68850 0.61560 0.61570 0.10580  -0.00030 -0.06070 129 ASN A O   
2021 C CB  . ASN A 129 ? 0.68470 0.66610 0.64180 0.15320  0.00810  -0.04900 129 ASN A CB  
2022 C CG  . ASN A 129 ? 0.77520 0.74740 0.71430 0.18100  0.01130  -0.04690 129 ASN A CG  
2023 O OD1 . ASN A 129 ? 0.74390 0.66260 0.64500 0.19000  0.01230  -0.05020 129 ASN A OD1 
2024 N ND2 . ASN A 129 ? 0.76970 0.79440 0.73300 0.19430  0.01300  -0.04040 129 ASN A ND2 
2031 N N   . PRO A 130 ? 0.62530 0.61540 0.61170 0.10030  -0.00040 -0.04870 130 PRO A N   
2032 C CA  . PRO A 130 ? 0.62870 0.63250 0.62280 0.08650  -0.00240 -0.04830 130 PRO A CA  
2033 C C   . PRO A 130 ? 0.64330 0.62780 0.62530 0.06840  -0.00780 -0.05060 130 PRO A C   
2034 O O   . PRO A 130 ? 0.64060 0.62060 0.62890 0.05980  -0.00930 -0.04770 130 PRO A O   
2035 C CB  . PRO A 130 ? 0.63530 0.67100 0.65950 0.08220  -0.00080 -0.04050 130 PRO A CB  
2036 C CG  . PRO A 130 ? 0.65820 0.70280 0.69040 0.09160  0.00170  -0.03850 130 PRO A CG  
2037 C CD  . PRO A 130 ? 0.62700 0.64320 0.63940 0.10000  0.00030  -0.04230 130 PRO A CD  
2045 N N   . PRO A 131 ? 0.61140 0.58730 0.57470 0.06000  -0.01080 -0.05570 131 PRO A N   
2046 C CA  . PRO A 131 ? 0.63320 0.60100 0.58610 0.03680  -0.01690 -0.05720 131 PRO A CA  
2047 C C   . PRO A 131 ? 0.60630 0.61130 0.59070 0.02720  -0.01860 -0.04810 131 PRO A C   
2048 O O   . PRO A 131 ? 0.62820 0.63230 0.61010 0.00980  -0.02200 -0.04700 131 PRO A O   
2049 C CB  . PRO A 131 ? 0.70550 0.67310 0.63880 0.02970  -0.02050 -0.06290 131 PRO A CB  
2050 C CG  . PRO A 131 ? 0.67070 0.62070 0.58770 0.05160  -0.01460 -0.06770 131 PRO A CG  
2051 C CD  . PRO A 131 ? 0.69520 0.66960 0.64290 0.06950  -0.00880 -0.06050 131 PRO A CD  
2059 N N   . ALA A 132 ? 0.58530 0.62100 0.59550 0.03830  -0.01530 -0.04110 132 ALA A N   
2060 C CA  . ALA A 132 ? 0.59800 0.66180 0.63140 0.03540  -0.01450 -0.03200 132 ALA A CA  
2061 C C   . ALA A 132 ? 0.52990 0.58110 0.56750 0.03300  -0.01260 -0.03050 132 ALA A C   
2062 O O   . ALA A 132 ? 0.56180 0.62660 0.60590 0.02270  -0.01380 -0.02610 132 ALA A O   
2063 C CB  . ALA A 132 ? 0.57810 0.65940 0.62640 0.04910  -0.00920 -0.02550 132 ALA A CB  
2069 N N   . LEU A 133 ? 0.54500 0.57540 0.57890 0.04290  -0.00960 -0.03310 133 LEU A N   
2070 C CA  . LEU A 133 ? 0.58590 0.60370 0.62110 0.04190  -0.00820 -0.03140 133 LEU A CA  
2071 C C   . LEU A 133 ? 0.63220 0.62330 0.64580 0.02910  -0.01130 -0.03510 133 LEU A C   
2072 O O   . LEU A 133 ? 0.64630 0.63750 0.66250 0.01950  -0.01090 -0.03140 133 LEU A O   
2073 C CB  . LEU A 133 ? 0.57140 0.58120 0.60720 0.05570  -0.00560 -0.03240 133 LEU A CB  
2074 C CG  . LEU A 133 ? 0.51080 0.54180 0.56380 0.06100  -0.00200 -0.02810 133 LEU A CG  
2075 C CD1 . LEU A 133 ? 0.54820 0.58150 0.60120 0.07000  -0.00100 -0.02940 133 LEU A CD1 
2076 C CD2 . LEU A 133 ? 0.54850 0.58370 0.61020 0.05660  0.00060  -0.02260 133 LEU A CD2 
2088 N N   . GLN A 134 ? 0.60950 0.57300 0.59690 0.02810  -0.01340 -0.04230 134 GLN A N   
2089 C CA  . GLN A 134 ? 0.60620 0.53270 0.56240 0.01170  -0.01560 -0.04650 134 GLN A CA  
2090 C C   . GLN A 134 ? 0.69080 0.64290 0.65590 -0.01390 -0.01920 -0.04270 134 GLN A C   
2091 O O   . GLN A 134 ? 0.65720 0.60280 0.61880 -0.02740 -0.01850 -0.03940 134 GLN A O   
2092 C CB  . GLN A 134 ? 0.70760 0.59790 0.62780 0.01340  -0.01670 -0.05560 134 GLN A CB  
2093 C CG  . GLN A 134 ? 0.73250 0.59250 0.63430 0.04070  -0.01180 -0.05870 134 GLN A CG  
2094 C CD  . GLN A 134 ? 0.78530 0.61670 0.65330 0.04800  -0.01090 -0.06720 134 GLN A CD  
2095 O OE1 . GLN A 134 ? 0.80340 0.62570 0.65350 0.02790  -0.01490 -0.07240 134 GLN A OE1 
2096 N NE2 . GLN A 134 ? 0.78930 0.61030 0.64730 0.07730  -0.00540 -0.06830 134 GLN A NE2 
2105 N N   . ASP A 135 ? 0.64670 0.63380 0.62360 -0.02030 -0.02280 -0.04200 135 ASP A N   
2106 C CA  . ASP A 135 ? 0.59040 0.61530 0.57730 -0.04340 -0.02690 -0.03710 135 ASP A CA  
2107 C C   . ASP A 135 ? 0.58660 0.64610 0.60320 -0.03880 -0.02260 -0.02670 135 ASP A C   
2108 O O   . ASP A 135 ? 0.58500 0.65770 0.60190 -0.05820 -0.02310 -0.02270 135 ASP A O   
2109 C CB  . ASP A 135 ? 0.62830 0.69160 0.62490 -0.04380 -0.03150 -0.03620 135 ASP A CB  
2110 C CG  . ASP A 135 ? 0.69900 0.72900 0.66060 -0.05320 -0.03620 -0.04720 135 ASP A CG  
2111 O OD1 . ASP A 135 ? 0.71280 0.68550 0.63980 -0.05730 -0.03480 -0.05540 135 ASP A OD1 
2112 O OD2 . ASP A 135 ? 0.67490 0.73270 0.63930 -0.05440 -0.04060 -0.04740 135 ASP A OD2 
2117 N N   . ALA A 136 ? 0.55250 0.62500 0.59050 -0.01460 -0.01750 -0.02210 136 ALA A N   
2118 C CA  . ALA A 136 ? 0.56360 0.66260 0.62290 -0.00710 -0.01200 -0.01280 136 ALA A CA  
2119 C C   . ALA A 136 ? 0.57630 0.64730 0.62710 -0.01140 -0.00880 -0.01320 136 ALA A C   
2120 O O   . ALA A 136 ? 0.57110 0.66320 0.63050 -0.01820 -0.00570 -0.00660 136 ALA A O   
2121 C CB  . ALA A 136 ? 0.57260 0.67820 0.64550 0.01690  -0.00670 -0.00930 136 ALA A CB  
2127 N N   . TYR A 137 ? 0.59480 0.62210 0.62810 -0.00530 -0.00900 -0.01980 137 TYR A N   
2128 C CA  . TYR A 137 ? 0.63390 0.63320 0.65560 -0.00680 -0.00640 -0.01930 137 TYR A CA  
2129 C C   . TYR A 137 ? 0.63730 0.62480 0.64040 -0.03250 -0.00800 -0.01890 137 TYR A C   
2130 O O   . TYR A 137 ? 0.64360 0.63280 0.64720 -0.03960 -0.00440 -0.01360 137 TYR A O   
2131 C CB  . TYR A 137 ? 0.66370 0.62440 0.66810 0.00810  -0.00680 -0.02500 137 TYR A CB  
2132 C CG  . TYR A 137 ? 0.68520 0.61930 0.67690 0.01140  -0.00460 -0.02300 137 TYR A CG  
2133 C CD1 . TYR A 137 ? 0.68940 0.64080 0.69620 0.01340  -0.00090 -0.01720 137 TYR A CD1 
2134 C CD2 . TYR A 137 ? 0.77100 0.65960 0.73070 0.01490  -0.00530 -0.02660 137 TYR A CD2 
2135 C CE1 . TYR A 137 ? 0.68950 0.61790 0.68290 0.01640  0.00070  -0.01510 137 TYR A CE1 
2136 C CE2 . TYR A 137 ? 0.84320 0.70760 0.78860 0.02030  -0.00340 -0.02330 137 TYR A CE2 
2137 C CZ  . TYR A 137 ? 0.77870 0.66540 0.74260 0.01970  -0.00090 -0.01770 137 TYR A CZ  
2138 O OH  . TYR A 137 ? 0.85270 0.71650 0.80060 0.02500  0.00060  -0.01420 137 TYR A OH  
2148 N N   . TYR A 138 ? 0.63980 0.61340 0.62260 -0.04900 -0.01290 -0.02450 138 TYR A N   
2149 C CA  . TYR A 138 ? 0.65520 0.61650 0.61520 -0.08110 -0.01480 -0.02450 138 TYR A CA  
2150 C C   . TYR A 138 ? 0.66650 0.69040 0.65500 -0.09600 -0.01370 -0.01470 138 TYR A C   
2151 O O   . TYR A 138 ? 0.74890 0.77170 0.72850 -0.11730 -0.01140 -0.01040 138 TYR A O   
2152 C CB  . TYR A 138 ? 0.71990 0.65830 0.65070 -0.09880 -0.02090 -0.03320 138 TYR A CB  
2153 C CG  . TYR A 138 ? 0.74790 0.66930 0.64790 -0.13950 -0.02360 -0.03430 138 TYR A CG  
2154 C CD1 . TYR A 138 ? 0.84860 0.69130 0.69580 -0.15080 -0.02180 -0.04040 138 TYR A CD1 
2155 C CD2 . TYR A 138 ? 0.75380 0.73800 0.67390 -0.16710 -0.02760 -0.02860 138 TYR A CD2 
2156 C CE1 . TYR A 138 ? 0.82900 0.64790 0.64050 -0.19350 -0.02370 -0.04180 138 TYR A CE1 
2157 C CE2 . TYR A 138 ? 0.76920 0.74310 0.66020 -0.21080 -0.03060 -0.02940 138 TYR A CE2 
2158 C CZ  . TYR A 138 ? 0.79900 0.68600 0.63370 -0.22640 -0.02850 -0.03650 138 TYR A CZ  
2159 O OH  . TYR A 138 ? 0.98230 0.85100 0.78080 -0.27510 -0.03090 -0.03760 138 TYR A OH  
2169 N N   . ARG A 139 ? 0.61210 0.69180 0.63290 -0.08340 -0.01420 -0.01000 139 ARG A N   
2170 C CA  . ARG A 139 ? 0.62380 0.76990 0.67190 -0.08940 -0.01170 0.00120  139 ARG A CA  
2171 C C   . ARG A 139 ? 0.61850 0.76910 0.68050 -0.07080 -0.00240 0.00820  139 ARG A C   
2172 O O   . ARG A 139 ? 0.57890 0.76490 0.65050 -0.08150 0.00200  0.01660  139 ARG A O   
2173 C CB  . ARG A 139 ? 0.64090 0.84000 0.71250 -0.07610 -0.01430 0.00530  139 ARG A CB  
2174 C CG  . ARG A 139 ? 0.71720 0.94720 0.78240 -0.10480 -0.02360 0.00380  139 ARG A CG  
2175 C CD  . ARG A 139 ? 0.83090 1.08540 0.90520 -0.08970 -0.02840 0.00320  139 ARG A CD  
2176 N NE  . ARG A 139 ? 0.82680 1.13830 0.93140 -0.06200 -0.02370 0.01540  139 ARG A NE  
2177 C CZ  . ARG A 139 ? 0.80340 1.18210 0.93000 -0.06160 -0.02090 0.02820  139 ARG A CZ  
2178 N NH1 . ARG A 139 ? 0.77500 1.18230 0.90200 -0.09230 -0.02270 0.03120  139 ARG A NH1 
2179 N NH2 . ARG A 139 ? 0.81150 1.22970 0.95720 -0.02880 -0.01510 0.03920  139 ARG A NH2 
2193 N N   . ALA A 140 ? 0.62410 0.74200 0.68570 -0.04470 0.00090  0.00490  140 ALA A N   
2194 C CA  . ALA A 140 ? 0.61640 0.72960 0.68320 -0.02980 0.00890  0.00960  140 ALA A CA  
2195 C C   . ALA A 140 ? 0.65180 0.73900 0.70020 -0.04790 0.01070  0.01020  140 ALA A C   
2196 O O   . ALA A 140 ? 0.58720 0.69530 0.64240 -0.04850 0.01750  0.01770  140 ALA A O   
2197 C CB  . ALA A 140 ? 0.60930 0.68920 0.67310 -0.00620 0.01000  0.00450  140 ALA A CB  
2203 N N   . ARG A 141 ? 0.64520 0.68350 0.66590 -0.06100 0.00570  0.00300  141 ARG A N   
2204 C CA  . ARG A 141 ? 0.67570 0.67930 0.67060 -0.07870 0.00790  0.00430  141 ARG A CA  
2205 C C   . ARG A 141 ? 0.65990 0.70310 0.65920 -0.10880 0.00990  0.01180  141 ARG A C   
2206 O O   . ARG A 141 ? 0.66700 0.70200 0.65560 -0.12060 0.01530  0.01720  141 ARG A O   
2207 C CB  . ARG A 141 ? 0.69710 0.63600 0.65340 -0.08540 0.00310  -0.00420 141 ARG A CB  
2208 C CG  . ARG A 141 ? 0.83790 0.73230 0.78010 -0.05890 0.00420  -0.00720 141 ARG A CG  
2209 C CD  . ARG A 141 ? 0.95360 0.78510 0.85420 -0.05830 0.00130  -0.01430 141 ARG A CD  
2210 N NE  . ARG A 141 ? 1.13650 0.93890 1.02710 -0.02880 0.00210  -0.01500 141 ARG A NE  
2211 C CZ  . ARG A 141 ? 1.10320 0.85270 0.95650 -0.02350 0.00430  -0.01340 141 ARG A CZ  
2212 N NH1 . ARG A 141 ? 1.22450 0.93250 1.04110 -0.04790 0.00690  -0.01160 141 ARG A NH1 
2213 N NH2 . ARG A 141 ? 0.99810 0.73710 0.84840 0.00640  0.00400  -0.01270 141 ARG A NH2 
2227 N N   . ALA A 142 ? 0.71240 0.80340 0.72720 -0.12250 0.00560  0.01300  142 ALA A N   
2228 C CA  . ALA A 142 ? 0.67270 0.81720 0.69540 -0.15390 0.00630  0.02100  142 ALA A CA  
2229 C C   . ALA A 142 ? 0.62420 0.84330 0.68440 -0.13690 0.01420  0.03330  142 ALA A C   
2230 O O   . ALA A 142 ? 0.67120 0.94700 0.74230 -0.15970 0.01660  0.04260  142 ALA A O   
2231 C CB  . ALA A 142 ? 0.68100 0.84960 0.70090 -0.17830 -0.00330 0.01720  142 ALA A CB  
2237 N N   . GLY A 143 ? 0.60890 0.82900 0.68530 -0.09820 0.01890  0.03410  143 GLY A N   
2238 C CA  . GLY A 143 ? 0.62730 0.90330 0.72920 -0.07550 0.02860  0.04520  143 GLY A CA  
2239 C C   . GLY A 143 ? 0.67290 0.98520 0.79540 -0.04700 0.02880  0.04800  143 GLY A C   
2240 O O   . GLY A 143 ? 0.71200 1.05240 0.84660 -0.01890 0.03880  0.05620  143 GLY A O   
2244 N N   . GLU A 144 ? 0.64930 0.95810 0.77140 -0.05120 0.01930  0.04210  144 GLU A N   
2245 C CA  . GLU A 144 ? 0.61570 0.95530 0.75310 -0.02470 0.01930  0.04570  144 GLU A CA  
2246 C C   . GLU A 144 ? 0.61010 0.88650 0.73430 -0.00630 0.01770  0.03560  144 GLU A C   
2247 O O   . GLU A 144 ? 0.59590 0.85310 0.71320 -0.01350 0.00930  0.02800  144 GLU A O   
2248 C CB  . GLU A 144 ? 0.69660 1.08840 0.84330 -0.04440 0.00960  0.04790  144 GLU A CB  
2249 C CG  . GLU A 144 ? 0.73670 1.20040 0.89690 -0.07040 0.00960  0.05810  144 GLU A CG  
2250 C CD  . GLU A 144 ? 0.86110 1.29790 0.99990 -0.11830 0.00160  0.05030  144 GLU A CD  
2251 O OE1 . GLU A 144 ? 0.85010 1.29050 0.98450 -0.13790 0.00670  0.05430  144 GLU A OE1 
2252 O OE2 . GLU A 144 ? 0.90070 1.30800 1.02220 -0.13630 -0.00880 0.04020  144 GLU A OE2 
2259 N N   . ALA A 145 ? 0.64120 0.88750 0.76030 0.01650  0.02620  0.03580  145 ALA A N   
2260 C CA  . ALA A 145 ? 0.56720 0.75890 0.67360 0.02950  0.02520  0.02710  145 ALA A CA  
2261 C C   . ALA A 145 ? 0.52810 0.72450 0.63680 0.05590  0.02990  0.03060  145 ALA A C   
2262 O O   . ALA A 145 ? 0.51060 0.66570 0.60790 0.06490  0.03060  0.02460  145 ALA A O   
2263 C CB  . ALA A 145 ? 0.63030 0.78220 0.72380 0.03280  0.03020  0.02400  145 ALA A CB  
2269 N N   . ALA A 146 ? 0.48600 0.73240 0.60650 0.06800  0.03340  0.04100  146 ALA A N   
2270 C CA  . ALA A 146 ? 0.53120 0.77420 0.64600 0.09660  0.03980  0.04620  146 ALA A CA  
2271 C C   . ALA A 146 ? 0.51750 0.73090 0.62560 0.09370  0.03290  0.03860  146 ALA A C   
2272 O O   . ALA A 146 ? 0.56170 0.73590 0.65450 0.10760  0.03790  0.03660  146 ALA A O   
2273 C CB  . ALA A 146 ? 0.53350 0.84340 0.66230 0.11210  0.04330  0.06030  146 ALA A CB  
2279 N N   . ASN A 147 ? 0.50020 0.73040 0.61610 0.07390  0.02190  0.03400  147 ASN A N   
2280 C CA  . ASN A 147 ? 0.53830 0.74400 0.64710 0.07230  0.01630  0.02700  147 ASN A CA  
2281 C C   . ASN A 147 ? 0.49180 0.64500 0.58920 0.06650  0.01580  0.01650  147 ASN A C   
2282 O O   . ASN A 147 ? 0.51000 0.63830 0.59920 0.07440  0.01750  0.01380  147 ASN A O   
2283 C CB  . ASN A 147 ? 0.52280 0.75530 0.63660 0.05250  0.00530  0.02380  147 ASN A CB  
2284 C CG  . ASN A 147 ? 0.56190 0.85430 0.68720 0.05970  0.00380  0.03480  147 ASN A CG  
2285 O OD1 . ASN A 147 ? 0.63500 0.97440 0.77130 0.04480  -0.00010 0.03930  147 ASN A OD1 
2286 N ND2 . ASN A 147 ? 0.62330 0.91710 0.74470 0.08180  0.00700  0.04020  147 ASN A ND2 
2293 N N   . PHE A 148 ? 0.52170 0.66080 0.61720 0.05240  0.01360  0.01160  148 PHE A N   
2294 C CA  . PHE A 148 ? 0.53810 0.63590 0.62340 0.05000  0.01250  0.00340  148 PHE A CA  
2295 C C   . PHE A 148 ? 0.54180 0.61910 0.62030 0.06370  0.02000  0.00490  148 PHE A C   
2296 O O   . PHE A 148 ? 0.57170 0.62780 0.64360 0.06480  0.01920  0.00010  148 PHE A O   
2297 C CB  . PHE A 148 ? 0.53900 0.62410 0.61900 0.03620  0.01020  0.00040  148 PHE A CB  
2298 C CG  . PHE A 148 ? 0.52940 0.57870 0.59790 0.03640  0.00770  -0.00670 148 PHE A CG  
2299 C CD1 . PHE A 148 ? 0.59190 0.62810 0.65410 0.03590  0.00260  -0.01310 148 PHE A CD1 
2300 C CD2 . PHE A 148 ? 0.59710 0.62980 0.65990 0.03920  0.01080  -0.00630 148 PHE A CD2 
2301 C CE1 . PHE A 148 ? 0.59440 0.60720 0.64710 0.04070  0.00100  -0.01770 148 PHE A CE1 
2302 C CE2 . PHE A 148 ? 0.63170 0.64070 0.68500 0.04140  0.00770  -0.01130 148 PHE A CE2 
2303 C CZ  . PHE A 148 ? 0.59620 0.59800 0.64550 0.04340  0.00290  -0.01640 148 PHE A CZ  
2313 N N   . CYS A 149 ? 0.47610 0.55980 0.55280 0.07330  0.02790  0.01160  149 CYS A N   
2314 C CA  . CYS A 149 ? 0.56590 0.62000 0.62640 0.08450  0.03580  0.01200  149 CYS A CA  
2315 C C   . CYS A 149 ? 0.57640 0.61940 0.62740 0.09430  0.03910  0.01390  149 CYS A C   
2316 O O   . CYS A 149 ? 0.60590 0.61730 0.64180 0.09110  0.04070  0.00960  149 CYS A O   
2317 C CB  . CYS A 149 ? 0.60430 0.66450 0.65920 0.09660  0.04550  0.01900  149 CYS A CB  
2318 S SG  . CYS A 149 ? 0.63200 0.69640 0.69130 0.08350  0.04380  0.01730  149 CYS A SG  
2324 N N   . ALA A 150 ? 0.57770 0.64810 0.63550 0.10450  0.04010  0.02100  150 ALA A N   
2325 C CA  . ALA A 150 ? 0.55260 0.61020 0.59820 0.11440  0.04340  0.02410  150 ALA A CA  
2326 C C   . ALA A 150 ? 0.52420 0.56880 0.57100 0.09940  0.03650  0.01580  150 ALA A C   
2327 O O   . ALA A 150 ? 0.56880 0.58620 0.59890 0.09980  0.04070  0.01550  150 ALA A O   
2328 C CB  . ALA A 150 ? 0.55340 0.65170 0.60840 0.12780  0.04320  0.03370  150 ALA A CB  
2334 N N   . LEU A 151 ? 0.52030 0.58230 0.58310 0.08600  0.02710  0.00960  151 LEU A N   
2335 C CA  . LEU A 151 ? 0.49240 0.54650 0.55560 0.07660  0.02190  0.00240  151 LEU A CA  
2336 C C   . LEU A 151 ? 0.55670 0.58690 0.61190 0.07000  0.02320  -0.00240 151 LEU A C   
2337 O O   . LEU A 151 ? 0.54990 0.57200 0.59890 0.06570  0.02430  -0.00410 151 LEU A O   
2338 C CB  . LEU A 151 ? 0.54220 0.61160 0.61540 0.06750  0.01310  -0.00310 151 LEU A CB  
2339 C CG  . LEU A 151 ? 0.52510 0.61920 0.60240 0.06740  0.00900  -0.00090 151 LEU A CG  
2340 C CD1 . LEU A 151 ? 0.53290 0.63020 0.61010 0.05410  0.00120  -0.00750 151 LEU A CD1 
2341 C CD2 . LEU A 151 ? 0.57000 0.66220 0.64180 0.07240  0.01010  -0.00070 151 LEU A CD2 
2353 N N   . ILE A 152 ? 0.55520 0.57800 0.60990 0.06720  0.02300  -0.00420 152 ILE A N   
2354 C CA  . ILE A 152 ? 0.56890 0.57380 0.61440 0.06000  0.02320  -0.00820 152 ILE A CA  
2355 C C   . ILE A 152 ? 0.51020 0.49180 0.53580 0.05890  0.03060  -0.00600 152 ILE A C   
2356 O O   . ILE A 152 ? 0.52940 0.50600 0.54870 0.04770  0.02970  -0.00890 152 ILE A O   
2357 C CB  . ILE A 152 ? 0.60920 0.60710 0.65230 0.05920  0.02320  -0.00890 152 ILE A CB  
2358 C CG1 . ILE A 152 ? 0.60560 0.61650 0.66030 0.05700  0.01650  -0.01090 152 ILE A CG1 
2359 C CG2 . ILE A 152 ? 0.55540 0.53730 0.58570 0.05080  0.02270  -0.01270 152 ILE A CG2 
2360 C CD1 . ILE A 152 ? 0.65130 0.65490 0.70180 0.05570  0.01730  -0.01000 152 ILE A CD1 
2372 N N   . LEU A 153 ? 0.52040 0.48650 0.53220 0.07050  0.03890  -0.00020 153 LEU A N   
2373 C CA  . LEU A 153 ? 0.53850 0.46810 0.51990 0.07150  0.04800  0.00240  153 LEU A CA  
2374 C C   . LEU A 153 ? 0.61530 0.54610 0.59460 0.06560  0.04770  0.00340  153 LEU A C   
2375 O O   . LEU A 153 ? 0.63230 0.53660 0.58950 0.05180  0.05110  0.00180  153 LEU A O   
2376 C CB  . LEU A 153 ? 0.57690 0.49330 0.54280 0.09370  0.05820  0.01070  153 LEU A CB  
2377 C CG  . LEU A 153 ? 0.64660 0.55310 0.60440 0.10030  0.06270  0.01050  153 LEU A CG  
2378 C CD1 . LEU A 153 ? 0.66720 0.59180 0.62720 0.12600  0.07030  0.02050  153 LEU A CD1 
2379 C CD2 . LEU A 153 ? 0.67310 0.52490 0.59020 0.09320  0.07000  0.00660  153 LEU A CD2 
2391 N N   . ALA A 154 ? 0.57340 0.53460 0.57280 0.07310  0.04360  0.00600  154 ALA A N   
2392 C CA  . ALA A 154 ? 0.58970 0.55360 0.58590 0.06950  0.04410  0.00760  154 ALA A CA  
2393 C C   . ALA A 154 ? 0.55760 0.53470 0.56340 0.05120  0.03860  0.00090  154 ALA A C   
2394 O O   . ALA A 154 ? 0.61940 0.58430 0.61040 0.03870  0.04240  0.00150  154 ALA A O   
2395 C CB  . ALA A 154 ? 0.58980 0.58470 0.60280 0.08170  0.04020  0.01130  154 ALA A CB  
2401 N N   . TYR A 155 ? 0.53900 0.54200 0.56690 0.04970  0.03030  -0.00460 155 TYR A N   
2402 C CA  . TYR A 155 ? 0.56540 0.58840 0.60270 0.03880  0.02570  -0.00940 155 TYR A CA  
2403 C C   . TYR A 155 ? 0.61510 0.62630 0.63890 0.02190  0.02750  -0.01080 155 TYR A C   
2404 O O   . TYR A 155 ? 0.65770 0.68570 0.68190 0.00830  0.02710  -0.01130 155 TYR A O   
2405 C CB  . TYR A 155 ? 0.53670 0.57910 0.59130 0.04520  0.01810  -0.01390 155 TYR A CB  
2406 C CG  . TYR A 155 ? 0.54840 0.60320 0.61110 0.05470  0.01520  -0.01490 155 TYR A CG  
2407 C CD1 . TYR A 155 ? 0.61070 0.68110 0.67550 0.05600  0.01550  -0.01570 155 TYR A CD1 
2408 C CD2 . TYR A 155 ? 0.54520 0.59690 0.61080 0.06000  0.01240  -0.01510 155 TYR A CD2 
2409 C CE1 . TYR A 155 ? 0.55890 0.63530 0.62470 0.06350  0.01290  -0.01780 155 TYR A CE1 
2410 C CE2 . TYR A 155 ? 0.54800 0.60810 0.61530 0.06340  0.00890  -0.01710 155 TYR A CE2 
2411 C CZ  . TYR A 155 ? 0.60790 0.67730 0.67350 0.06580  0.00900  -0.01900 155 TYR A CZ  
2412 O OH  . TYR A 155 ? 0.59550 0.66810 0.65670 0.06810  0.00550  -0.02210 155 TYR A OH  
2422 N N   . CYS A 156 ? 0.55650 0.54170 0.56640 0.02070  0.02950  -0.01130 156 CYS A N   
2423 C CA  . CYS A 156 ? 0.66230 0.63300 0.65410 0.00180  0.02990  -0.01400 156 CYS A CA  
2424 C C   . CYS A 156 ? 0.68020 0.60900 0.63650 -0.01100 0.03920  -0.01150 156 CYS A C   
2425 O O   . CYS A 156 ? 0.71840 0.62740 0.65120 -0.03210 0.04000  -0.01460 156 CYS A O   
2426 C CB  . CYS A 156 ? 0.57270 0.52950 0.55970 0.00620  0.02840  -0.01640 156 CYS A CB  
2427 S SG  . CYS A 156 ? 0.64210 0.63730 0.65870 0.01480  0.01790  -0.01920 156 CYS A SG  
2433 N N   . ASN A 157 ? 0.69130 0.60300 0.63820 0.00040  0.04610  -0.00590 157 ASN A N   
2434 C CA  . ASN A 157 ? 0.70650 0.56750 0.61130 -0.00800 0.05680  -0.00210 157 ASN A CA  
2435 C C   . ASN A 157 ? 0.75710 0.56450 0.62430 -0.00790 0.06350  -0.00360 157 ASN A C   
2436 O O   . ASN A 157 ? 0.75400 0.51800 0.58100 -0.03020 0.06860  -0.00580 157 ASN A O   
2437 C CB  . ASN A 157 ? 0.71510 0.58390 0.61140 -0.03840 0.05640  -0.00320 157 ASN A CB  
2438 C CG  . ASN A 157 ? 0.84060 0.73220 0.74940 -0.03410 0.05800  0.00200  157 ASN A CG  
2439 O OD1 . ASN A 157 ? 0.80600 0.75160 0.74970 -0.03340 0.05100  0.00030  157 ASN A OD1 
2440 N ND2 . ASN A 157 ? 0.80460 0.65210 0.68070 -0.02840 0.06820  0.00880  157 ASN A ND2 
2447 N N   . LYS A 158 ? 0.71040 0.52030 0.58760 0.01620  0.06390  -0.00250 158 LYS A N   
2448 C CA  . LYS A 158 ? 0.81590 0.57810 0.65810 0.02470  0.07220  -0.00280 158 LYS A CA  
2449 C C   . LYS A 158 ? 0.76480 0.51490 0.59960 0.05910  0.08160  0.00640  158 LYS A C   
2450 O O   . LYS A 158 ? 0.72850 0.52590 0.60060 0.07540  0.07680  0.01060  158 LYS A O   
2451 C CB  . LYS A 158 ? 0.77490 0.55970 0.63630 0.02230  0.06480  -0.00870 158 LYS A CB  
2452 C CG  . LYS A 158 ? 0.74660 0.53700 0.60370 -0.00910 0.05680  -0.01670 158 LYS A CG  
2453 C CD  . LYS A 158 ? 0.95150 0.67690 0.75130 -0.02630 0.06480  -0.02050 158 LYS A CD  
2454 C CE  . LYS A 158 ? 0.94730 0.68700 0.74230 -0.06320 0.05540  -0.02790 158 LYS A CE  
2455 N NZ  . LYS A 158 ? 0.98590 0.76480 0.80150 -0.08340 0.04980  -0.02650 158 LYS A NZ  
2469 N N   . THR A 159 ? 0.80960 0.49660 0.59280 0.07050  0.09530  0.00980  159 THR A N   
2470 C CA  . THR A 159 ? 0.82620 0.50370 0.59750 0.10890  0.10600  0.02020  159 THR A CA  
2471 C C   . THR A 159 ? 0.93800 0.61760 0.70900 0.12510  0.10960  0.01930  159 THR A C   
2472 O O   . THR A 159 ? 0.93360 0.59240 0.69110 0.10720  0.10790  0.01050  159 THR A O   
2473 C CB  . THR A 159 ? 0.95300 0.55460 0.66040 0.12000  0.12180  0.02660  159 THR A CB  
2474 O OG1 . THR A 159 ? 1.02910 0.55950 0.68210 0.10110  0.12870  0.01890  159 THR A OG1 
2475 C CG2 . THR A 159 ? 0.93380 0.53580 0.64110 0.10550  0.11950  0.02960  159 THR A CG2 
2483 N N   . VAL A 160 ? 0.91150 0.62220 0.69790 0.15880  0.11460  0.02910  160 VAL A N   
2484 C CA  . VAL A 160 ? 0.84660 0.56460 0.63190 0.17760  0.12050  0.03070  160 VAL A CA  
2485 C C   . VAL A 160 ? 0.91960 0.55400 0.63800 0.18280  0.13510  0.02770  160 VAL A C   
2486 O O   . VAL A 160 ? 0.96270 0.53610 0.62980 0.19610  0.14750  0.03240  160 VAL A O   
2487 C CB  . VAL A 160 ? 0.81500 0.58310 0.62200 0.21400  0.12560  0.04440  160 VAL A CB  
2488 C CG1 . VAL A 160 ? 0.86940 0.63640 0.66230 0.23960  0.13730  0.04870  160 VAL A CG1 
2489 C CG2 . VAL A 160 ? 0.76720 0.61590 0.63690 0.20140  0.10980  0.04450  160 VAL A CG2 
2499 N N   . GLY A 161 ? 0.96530 0.59070 0.67810 0.17180  0.13410  0.01970  161 GLY A N   
2500 C CA  . GLY A 161 ? 1.02100 0.56460 0.66680 0.17200  0.14660  0.01440  161 GLY A CA  
2501 C C   . GLY A 161 ? 1.01850 0.51700 0.63630 0.12810  0.13940  0.00150  161 GLY A C   
2502 O O   . GLY A 161 ? 1.03860 0.46990 0.59920 0.11980  0.14720  -0.00560 161 GLY A O   
2506 N N   . GLU A 162 ? 0.97230 0.50820 0.62650 0.09910  0.12500  -0.00170 162 GLU A N   
2507 C CA  . GLU A 162 ? 1.05610 0.56630 0.69010 0.05540  0.11720  -0.01220 162 GLU A CA  
2508 C C   . GLU A 162 ? 1.00960 0.55800 0.67110 0.03490  0.10420  -0.02090 162 GLU A C   
2509 O O   . GLU A 162 ? 0.92990 0.54170 0.64450 0.04640  0.09620  -0.01860 162 GLU A O   
2510 C CB  . GLU A 162 ? 1.02430 0.56730 0.68720 0.03630  0.10850  -0.01040 162 GLU A CB  
2511 C CG  . GLU A 162 ? 1.12850 0.63350 0.75490 -0.00680 0.10610  -0.01760 162 GLU A CG  
2512 C CD  . GLU A 162 ? 1.15070 0.68090 0.79700 -0.02020 0.10230  -0.01330 162 GLU A CD  
2513 O OE1 . GLU A 162 ? 1.07840 0.64770 0.76150 0.00600  0.10200  -0.00520 162 GLU A OE1 
2514 O OE2 . GLU A 162 ? 1.21790 0.73150 0.84180 -0.05880 0.09970  -0.01780 162 GLU A OE2 
2521 N N   . LEU A 163 ? 1.03720 0.54480 0.65800 0.00290  0.10200  -0.03060 163 LEU A N   
2522 C CA  . LEU A 163 ? 1.00200 0.54680 0.64450 -0.01780 0.08860  -0.03820 163 LEU A CA  
2523 C C   . LEU A 163 ? 0.88220 0.50590 0.58680 -0.03400 0.07170  -0.03770 163 LEU A C   
2524 O O   . LEU A 163 ? 0.94680 0.57770 0.65350 -0.05510 0.06820  -0.03770 163 LEU A O   
2525 C CB  . LEU A 163 ? 1.09360 0.57980 0.67470 -0.05220 0.08900  -0.04870 163 LEU A CB  
2526 C CG  . LEU A 163 ? 1.21970 0.74640 0.81770 -0.07740 0.07350  -0.05630 163 LEU A CG  
2527 C CD1 . LEU A 163 ? 1.10380 0.63050 0.70290 -0.05170 0.07710  -0.05630 163 LEU A CD1 
2528 C CD2 . LEU A 163 ? 1.21500 0.69740 0.75680 -0.12290 0.07030  -0.06640 163 LEU A CD2 
2540 N N   . GLY A 164 ? 0.84590 0.52570 0.59670 -0.02340 0.06260  -0.03680 164 GLY A N   
2541 C CA  . GLY A 164 ? 0.79730 0.54600 0.60100 -0.03180 0.04830  -0.03590 164 GLY A CA  
2542 C C   . GLY A 164 ? 0.82760 0.60890 0.64290 -0.04720 0.03570  -0.04070 164 GLY A C   
2543 O O   . GLY A 164 ? 0.84770 0.60630 0.63980 -0.04610 0.03730  -0.04390 164 GLY A O   
2547 N N   . ASP A 165 ? 0.75060 0.58680 0.59980 -0.05890 0.02360  -0.04030 165 ASP A N   
2548 C CA  . ASP A 165 ? 0.72020 0.59840 0.58430 -0.06870 0.01070  -0.04250 165 ASP A CA  
2549 C C   . ASP A 165 ? 0.69300 0.61730 0.60200 -0.04480 0.00500  -0.03730 165 ASP A C   
2550 O O   . ASP A 165 ? 0.66910 0.61620 0.60430 -0.03590 0.00500  -0.03390 165 ASP A O   
2551 C CB  . ASP A 165 ? 0.72590 0.63530 0.58790 -0.10060 0.00190  -0.04510 165 ASP A CB  
2552 C CG  . ASP A 165 ? 0.77460 0.73050 0.64590 -0.11040 -0.01170 -0.04630 165 ASP A CG  
2553 O OD1 . ASP A 165 ? 0.85180 0.78150 0.69200 -0.12060 -0.01300 -0.05090 165 ASP A OD1 
2554 O OD2 . ASP A 165 ? 0.72010 0.73920 0.62760 -0.10540 -0.02070 -0.04210 165 ASP A OD2 
2559 N N   . VAL A 166 ? 0.67160 0.55340 0.64530 0.04840  0.02350  -0.01190 166 VAL A N   
2560 C CA  . VAL A 166 ? 0.64820 0.54090 0.61570 0.04930  0.02320  -0.01040 166 VAL A CA  
2561 C C   . VAL A 166 ? 0.66160 0.56620 0.62960 0.04430  0.01700  -0.01430 166 VAL A C   
2562 O O   . VAL A 166 ? 0.64460 0.56400 0.61720 0.04170  0.01630  -0.01120 166 VAL A O   
2563 C CB  . VAL A 166 ? 0.63980 0.52320 0.59260 0.05600  0.02580  -0.01480 166 VAL A CB  
2564 C CG1 . VAL A 166 ? 0.59680 0.48810 0.54510 0.05580  0.02300  -0.01440 166 VAL A CG1 
2565 C CG2 . VAL A 166 ? 0.66730 0.54600 0.62230 0.06110  0.03390  -0.00940 166 VAL A CG2 
2575 N N   . ARG A 167 ? 0.66960 0.56960 0.63400 0.04310  0.01220  -0.02260 167 ARG A N   
2576 C CA  . ARG A 167 ? 0.65650 0.56970 0.62420 0.03930  0.00670  -0.02700 167 ARG A CA  
2577 C C   . ARG A 167 ? 0.64810 0.57880 0.62880 0.03240  0.00760  -0.02070 167 ARG A C   
2578 O O   . ARG A 167 ? 0.61360 0.56100 0.59710 0.03080  0.00640  -0.02210 167 ARG A O   
2579 C CB  . ARG A 167 ? 0.61580 0.52260 0.58060 0.03840  0.00090  -0.03590 167 ARG A CB  
2580 C CG  . ARG A 167 ? 0.60350 0.52460 0.57300 0.03620  -0.00520 -0.04140 167 ARG A CG  
2581 C CD  . ARG A 167 ? 0.66270 0.58740 0.64220 0.02970  -0.00930 -0.04510 167 ARG A CD  
2582 N NE  . ARG A 167 ? 0.68660 0.62410 0.68050 0.02230  -0.00570 -0.03720 167 ARG A NE  
2583 C CZ  . ARG A 167 ? 0.67140 0.63130 0.67380 0.01860  -0.00510 -0.03550 167 ARG A CZ  
2584 N NH1 . ARG A 167 ? 0.68340 0.65380 0.68420 0.02240  -0.00790 -0.04280 167 ARG A NH1 
2585 N NH2 . ARG A 167 ? 0.69380 0.66670 0.70700 0.01140  -0.00130 -0.02620 167 ARG A NH2 
2599 N N   . GLU A 168 ? 0.66120 0.58900 0.65060 0.02850  0.00970  -0.01360 168 GLU A N   
2600 C CA  . GLU A 168 ? 0.58550 0.53180 0.58600 0.02160  0.01100  -0.00410 168 GLU A CA  
2601 C C   . GLU A 168 ? 0.65110 0.60980 0.65000 0.02300  0.01380  0.00230  168 GLU A C   
2602 O O   . GLU A 168 ? 0.62120 0.60170 0.62190 0.01920  0.01340  0.00330  168 GLU A O   
2603 C CB  . GLU A 168 ? 0.64950 0.58690 0.66150 0.01760  0.01210  0.00490  168 GLU A CB  
2604 C CG  . GLU A 168 ? 0.66740 0.62480 0.69150 0.00890  0.01270  0.01720  168 GLU A CG  
2605 C CD  . GLU A 168 ? 0.71930 0.68940 0.74900 0.00200  0.00990  0.01270  168 GLU A CD  
2606 O OE1 . GLU A 168 ? 0.63430 0.59680 0.65960 0.00440  0.00640  -0.00040 168 GLU A OE1 
2607 O OE2 . GLU A 168 ? 0.77940 0.76920 0.81850 -0.00580 0.01130  0.02330  168 GLU A OE2 
2614 N N   . THR A 169 ? 0.65160 0.59840 0.64750 0.02840  0.01660  0.00560  169 THR A N   
2615 C CA  . THR A 169 ? 0.62690 0.58550 0.62350 0.02920  0.01830  0.01150  169 THR A CA  
2616 C C   . THR A 169 ? 0.65960 0.62920 0.65070 0.02960  0.01590  0.00250  169 THR A C   
2617 O O   . THR A 169 ? 0.62320 0.61270 0.61670 0.02620  0.01500  0.00360  169 THR A O   
2618 C CB  . THR A 169 ? 0.64260 0.58660 0.63880 0.03540  0.02220  0.01530  169 THR A CB  
2619 O OG1 . THR A 169 ? 0.62260 0.55640 0.62730 0.03600  0.02430  0.02270  169 THR A OG1 
2620 C CG2 . THR A 169 ? 0.61760 0.57470 0.61690 0.03560  0.02290  0.02110  169 THR A CG2 
2628 N N   . MET A 170 ? 0.63420 0.59130 0.61840 0.03410  0.01440  -0.00660 170 MET A N   
2629 C CA  . MET A 170 ? 0.62620 0.59050 0.60890 0.03520  0.01130  -0.01510 170 MET A CA  
2630 C C   . MET A 170 ? 0.59240 0.57630 0.57960 0.03100  0.00890  -0.02100 170 MET A C   
2631 O O   . MET A 170 ? 0.59480 0.59220 0.58440 0.03070  0.00730  -0.02720 170 MET A O   
2632 C CB  . MET A 170 ? 0.62410 0.57170 0.59970 0.04070  0.00920  -0.02110 170 MET A CB  
2633 C CG  . MET A 170 ? 0.70900 0.64030 0.67820 0.04520  0.01300  -0.01580 170 MET A CG  
2634 S SD  . MET A 170 ? 0.63410 0.57030 0.60920 0.04510  0.01630  -0.00880 170 MET A SD  
2635 C CE  . MET A 170 ? 0.67630 0.61930 0.65600 0.04450  0.01060  -0.01720 170 MET A CE  
2645 N N   . SER A 171 ? 0.59720 0.58380 0.58700 0.02760  0.00860  -0.02000 171 SER A N   
2646 C CA  . SER A 171 ? 0.63830 0.64700 0.63370 0.02310  0.00780  -0.02440 171 SER A CA  
2647 C C   . SER A 171 ? 0.61720 0.64930 0.61450 0.01860  0.01020  -0.01920 171 SER A C   
2648 O O   . SER A 171 ? 0.58940 0.64110 0.58770 0.01820  0.00980  -0.02790 171 SER A O   
2649 C CB  . SER A 171 ? 0.64620 0.65380 0.64680 0.01860  0.00740  -0.02120 171 SER A CB  
2650 O OG  . SER A 171 ? 0.77320 0.79910 0.77990 0.01620  0.00600  -0.02880 171 SER A OG  
2656 N N   . TYR A 172 ? 0.62590 0.65730 0.62400 0.01560  0.01250  -0.00560 172 TYR A N   
2657 C CA  . TYR A 172 ? 0.67690 0.73230 0.67510 0.01120  0.01370  0.00140  172 TYR A CA  
2658 C C   . TYR A 172 ? 0.60210 0.66400 0.59670 0.01420  0.01200  -0.00750 172 TYR A C   
2659 O O   . TYR A 172 ? 0.64190 0.72850 0.63490 0.01150  0.01150  -0.01350 172 TYR A O   
2660 C CB  . TYR A 172 ? 0.63730 0.68730 0.63920 0.00910  0.01520  0.01900  172 TYR A CB  
2661 C CG  . TYR A 172 ? 0.70070 0.75510 0.70960 0.00290  0.01650  0.03070  172 TYR A CG  
2662 C CD1 . TYR A 172 ? 0.70930 0.74040 0.72380 0.00360  0.01650  0.03140  172 TYR A CD1 
2663 C CD2 . TYR A 172 ? 0.70300 0.78550 0.71330 -0.00420 0.01760  0.04130  172 TYR A CD2 
2664 C CE1 . TYR A 172 ? 0.74460 0.77790 0.76920 -0.00310 0.01700  0.04220  172 TYR A CE1 
2665 C CE2 . TYR A 172 ? 0.74680 0.83330 0.76600 -0.01090 0.01890  0.05470  172 TYR A CE2 
2666 C CZ  . TYR A 172 ? 0.70600 0.76650 0.73390 -0.01060 0.01840  0.05500  172 TYR A CZ  
2667 O OH  . TYR A 172 ? 0.77040 0.83310 0.81060 -0.01840 0.01910  0.06830  172 TYR A OH  
2677 N N   . LEU A 173 ? 0.59660 0.63740 0.59050 0.01940  0.01110  -0.00900 173 LEU A N   
2678 C CA  . LEU A 173 ? 0.63920 0.68390 0.63330 0.02110  0.00880  -0.01620 173 LEU A CA  
2679 C C   . LEU A 173 ? 0.62910 0.68010 0.62420 0.02290  0.00630  -0.03330 173 LEU A C   
2680 O O   . LEU A 173 ? 0.59320 0.66090 0.58960 0.02150  0.00430  -0.04220 173 LEU A O   
2681 C CB  . LEU A 173 ? 0.59690 0.61810 0.59190 0.02560  0.00940  -0.01230 173 LEU A CB  
2682 C CG  . LEU A 173 ? 0.61670 0.63250 0.61400 0.02560  0.01240  0.00280  173 LEU A CG  
2683 C CD1 . LEU A 173 ? 0.60890 0.60610 0.60770 0.03040  0.01430  0.00490  173 LEU A CD1 
2684 C CD2 . LEU A 173 ? 0.65140 0.69040 0.65190 0.02090  0.01090  0.01040  173 LEU A CD2 
2696 N N   . PHE A 174 ? 0.61240 0.65080 0.60800 0.02640  0.00570  -0.03910 174 PHE A N   
2697 C CA  . PHE A 174 ? 0.58810 0.63290 0.58810 0.02930  0.00300  -0.05480 174 PHE A CA  
2698 C C   . PHE A 174 ? 0.63370 0.70960 0.63490 0.02530  0.00470  -0.06130 174 PHE A C   
2699 O O   . PHE A 174 ? 0.59890 0.68750 0.60440 0.02730  0.00310  -0.07640 174 PHE A O   
2700 C CB  . PHE A 174 ? 0.59290 0.62150 0.59400 0.03360  0.00110  -0.05740 174 PHE A CB  
2701 C CG  . PHE A 174 ? 0.59670 0.59800 0.59460 0.03830  -0.00060 -0.05300 174 PHE A CG  
2702 C CD1 . PHE A 174 ? 0.59420 0.58700 0.59180 0.03860  -0.00010 -0.04850 174 PHE A CD1 
2703 C CD2 . PHE A 174 ? 0.59420 0.58100 0.58960 0.04200  -0.00290 -0.05300 174 PHE A CD2 
2704 C CE1 . PHE A 174 ? 0.62670 0.59780 0.62120 0.04250  -0.00040 -0.04300 174 PHE A CE1 
2705 C CE2 . PHE A 174 ? 0.67020 0.63530 0.65990 0.04610  -0.00400 -0.04810 174 PHE A CE2 
2706 C CZ  . PHE A 174 ? 0.64160 0.59920 0.63080 0.04630  -0.00200 -0.04260 174 PHE A CZ  
2716 N N   . GLN A 175 ? 0.56090 0.64990 0.55930 0.01970  0.00810  -0.05020 175 GLN A N   
2717 C CA  . GLN A 175 ? 0.63820 0.76050 0.63620 0.01500  0.01100  -0.05350 175 GLN A CA  
2718 C C   . GLN A 175 ? 0.61350 0.75610 0.60670 0.01300  0.01040  -0.05790 175 GLN A C   
2719 O O   . GLN A 175 ? 0.62440 0.79570 0.61620 0.01150  0.01210  -0.06860 175 GLN A O   
2720 C CB  . GLN A 175 ? 0.69880 0.82920 0.69630 0.00830  0.01460  -0.03640 175 GLN A CB  
2721 C CG  . GLN A 175 ? 0.77390 0.88980 0.77780 0.00870  0.01450  -0.03500 175 GLN A CG  
2722 C CD  . GLN A 175 ? 0.79520 0.93570 0.80550 0.00680  0.01680  -0.04350 175 GLN A CD  
2723 O OE1 . GLN A 175 ? 0.78920 0.95490 0.79870 0.00750  0.01860  -0.05450 175 GLN A OE1 
2724 N NE2 . GLN A 175 ? 0.88280 1.01780 0.90070 0.00440  0.01670  -0.03960 175 GLN A NE2 
2733 N N   . HIS A 176 ? 0.57460 0.70480 0.56570 0.01300  0.00790  -0.05060 176 HIS A N   
2734 C CA  . HIS A 176 ? 0.65730 0.80550 0.64500 0.01060  0.00550  -0.05490 176 HIS A CA  
2735 C C   . HIS A 176 ? 0.62170 0.75650 0.61550 0.01520  0.00100  -0.07130 176 HIS A C   
2736 O O   . HIS A 176 ? 0.59870 0.73830 0.59270 0.01320  -0.00260 -0.07290 176 HIS A O   
2737 C CB  . HIS A 176 ? 0.59610 0.74320 0.58110 0.00700  0.00490  -0.03510 176 HIS A CB  
2738 C CG  . HIS A 176 ? 0.67260 0.83810 0.65340 0.00140  0.00820  -0.01810 176 HIS A CG  
2739 N ND1 . HIS A 176 ? 0.69670 0.89780 0.66990 -0.00410 0.00840  -0.01590 176 HIS A ND1 
2740 C CD2 . HIS A 176 ? 0.65630 0.80950 0.64020 0.00010  0.01110  -0.00220 176 HIS A CD2 
2741 C CE1 . HIS A 176 ? 0.73450 0.94440 0.70700 -0.00890 0.01150  0.00340  176 HIS A CE1 
2742 N NE2 . HIS A 176 ? 0.71700 0.89690 0.69750 -0.00650 0.01290  0.01130  176 HIS A NE2 
2750 N N   . ALA A 177 ? 0.60690 0.72500 0.60760 0.02080  0.00020  -0.08260 177 ALA A N   
2751 C CA  . ALA A 177 ? 0.59910 0.70120 0.60900 0.02520  -0.00450 -0.09630 177 ALA A CA  
2752 C C   . ALA A 177 ? 0.63400 0.74620 0.65100 0.02960  -0.00520 -0.11730 177 ALA A C   
2753 O O   . ALA A 177 ? 0.61240 0.74010 0.62780 0.03020  -0.00150 -0.11970 177 ALA A O   
2754 C CB  . ALA A 177 ? 0.58160 0.64950 0.59540 0.02930  -0.00550 -0.08690 177 ALA A CB  
2760 N N   . ASN A 178 ? 0.57080 0.67430 0.59840 0.03290  -0.01010 -0.13280 178 ASN A N   
2761 C CA  . ASN A 178 ? 0.61060 0.72100 0.64930 0.03870  -0.01160 -0.15520 178 ASN A CA  
2762 C C   . ASN A 178 ? 0.64640 0.72980 0.69540 0.04580  -0.01370 -0.15280 178 ASN A C   
2763 O O   . ASN A 178 ? 0.63130 0.68800 0.68970 0.04860  -0.01850 -0.15110 178 ASN A O   
2764 C CB  . ASN A 178 ? 0.58830 0.70040 0.63640 0.03880  -0.01690 -0.17410 178 ASN A CB  
2765 C CG  . ASN A 178 ? 0.66800 0.78720 0.73010 0.04600  -0.01830 -0.20000 178 ASN A CG  
2766 O OD1 . ASN A 178 ? 0.64500 0.77210 0.70950 0.05090  -0.01470 -0.20330 178 ASN A OD1 
2767 N ND2 . ASN A 178 ? 0.72780 0.84440 0.80170 0.04680  -0.02380 -0.21930 178 ASN A ND2 
2774 N N   . LEU A 179 ? 0.65320 0.74540 0.70110 0.04820  -0.01030 -0.15130 179 LEU A N   
2775 C CA  . LEU A 179 ? 0.66010 0.73280 0.71770 0.05530  -0.01330 -0.15030 179 LEU A CA  
2776 C C   . LEU A 179 ? 0.68970 0.78140 0.76000 0.06140  -0.01270 -0.16850 179 LEU A C   
2777 O O   . LEU A 179 ? 0.69000 0.77620 0.76710 0.06610  -0.01410 -0.16620 179 LEU A O   
2778 C CB  . LEU A 179 ? 0.65830 0.72130 0.70520 0.05270  -0.01130 -0.13050 179 LEU A CB  
2779 C CG  . LEU A 179 ? 0.72110 0.76560 0.75690 0.04830  -0.01090 -0.11290 179 LEU A CG  
2780 C CD1 . LEU A 179 ? 0.67510 0.71440 0.70050 0.04570  -0.00810 -0.09740 179 LEU A CD1 
2781 C CD2 . LEU A 179 ? 0.70740 0.72370 0.74990 0.05240  -0.01600 -0.11090 179 LEU A CD2 
2793 N N   . ASP A 180 ? 0.68600 0.80190 0.76010 0.06160  -0.01060 -0.18760 180 ASP A N   
2794 C CA  . ASP A 180 ? 0.76180 0.90120 0.84830 0.06770  -0.00810 -0.20670 180 ASP A CA  
2795 C C   . ASP A 180 ? 0.76100 0.87950 0.87030 0.07880  -0.01470 -0.21760 180 ASP A C   
2796 O O   . ASP A 180 ? 0.82380 0.95810 0.94670 0.08550  -0.01310 -0.22940 180 ASP A O   
2797 C CB  . ASP A 180 ? 0.75820 0.92820 0.84190 0.06600  -0.00440 -0.22690 180 ASP A CB  
2798 C CG  . ASP A 180 ? 0.78120 0.97650 0.84250 0.05530  0.00150  -0.21470 180 ASP A CG  
2799 O OD1 . ASP A 180 ? 0.84910 1.04050 0.90060 0.05000  0.00400  -0.19220 180 ASP A OD1 
2800 O OD2 . ASP A 180 ? 0.80600 1.02520 0.86010 0.05240  0.00320  -0.22760 180 ASP A OD2 
2805 N N   . SER A 181 ? 0.71420 0.79920 0.83000 0.08090  -0.02190 -0.21270 181 SER A N   
2806 C CA  . SER A 181 ? 0.77340 0.83590 0.91210 0.09120  -0.02930 -0.21890 181 SER A CA  
2807 C C   . SER A 181 ? 0.75360 0.79850 0.89110 0.09390  -0.03280 -0.19940 181 SER A C   
2808 O O   . SER A 181 ? 0.74890 0.77430 0.90410 0.10230  -0.04000 -0.19980 181 SER A O   
2809 C CB  . SER A 181 ? 0.71790 0.75300 0.86660 0.09130  -0.03590 -0.22130 181 SER A CB  
2810 O OG  . SER A 181 ? 0.92830 0.97370 1.09320 0.09520  -0.03700 -0.24840 181 SER A OG  
2816 N N   . CYS A 182 ? 0.66940 0.72070 0.78730 0.08700  -0.02850 -0.18280 182 CYS A N   
2817 C CA  . CYS A 182 ? 0.64270 0.67760 0.75630 0.08850  -0.03230 -0.16560 182 CYS A CA  
2818 C C   . CYS A 182 ? 0.63910 0.69440 0.76220 0.09260  -0.03200 -0.17120 182 CYS A C   
2819 O O   . CYS A 182 ? 0.65320 0.73780 0.77350 0.08850  -0.02490 -0.17740 182 CYS A O   
2820 C CB  . CYS A 182 ? 0.60630 0.63490 0.69620 0.07920  -0.02860 -0.14630 182 CYS A CB  
2821 S SG  . CYS A 182 ? 0.65890 0.66370 0.74020 0.07480  -0.02920 -0.13650 182 CYS A SG  
2827 N N   . LYS A 183 ? 0.68020 0.72160 0.81540 0.10040  -0.03990 -0.16760 183 LYS A N   
2828 C CA  . LYS A 183 ? 0.65380 0.71380 0.80220 0.10520  -0.04140 -0.17250 183 LYS A CA  
2829 C C   . LYS A 183 ? 0.67310 0.71530 0.81660 0.10680  -0.04960 -0.15610 183 LYS A C   
2830 O O   . LYS A 183 ? 0.69320 0.70790 0.83300 0.10960  -0.05610 -0.14560 183 LYS A O   
2831 C CB  . LYS A 183 ? 0.64700 0.71580 0.82450 0.11690  -0.04440 -0.19220 183 LYS A CB  
2832 C CG  . LYS A 183 ? 0.72690 0.82400 0.92130 0.12160  -0.04360 -0.20050 183 LYS A CG  
2833 C CD  . LYS A 183 ? 0.83780 0.93860 1.06460 0.13570  -0.04810 -0.21870 183 LYS A CD  
2834 C CE  . LYS A 183 ? 0.85060 0.97890 1.09740 0.14150  -0.04860 -0.22460 183 LYS A CE  
2835 N NZ  . LYS A 183 ? 0.96880 1.12030 1.24400 0.15220  -0.04470 -0.25010 183 LYS A NZ  
2849 N N   . ARG A 184 ? 0.67280 0.73260 0.81650 0.10440  -0.04940 -0.15380 184 ARG A N   
2850 C CA  . ARG A 184 ? 0.69330 0.74140 0.83180 0.10530  -0.05800 -0.14100 184 ARG A CA  
2851 C C   . ARG A 184 ? 0.69720 0.77020 0.85560 0.10890  -0.06120 -0.14820 184 ARG A C   
2852 O O   . ARG A 184 ? 0.65010 0.75130 0.81500 0.10430  -0.05330 -0.15650 184 ARG A O   
2853 C CB  . ARG A 184 ? 0.68220 0.72190 0.79420 0.09450  -0.05470 -0.12730 184 ARG A CB  
2854 C CG  . ARG A 184 ? 0.69370 0.73200 0.80090 0.09330  -0.06210 -0.11940 184 ARG A CG  
2855 C CD  . ARG A 184 ? 0.70410 0.72760 0.78530 0.08470  -0.05960 -0.10750 184 ARG A CD  
2856 N NE  . ARG A 184 ? 0.65730 0.65410 0.72300 0.08720  -0.06130 -0.09800 184 ARG A NE  
2857 C CZ  . ARG A 184 ? 0.69480 0.67730 0.73880 0.08150  -0.05710 -0.08880 184 ARG A CZ  
2858 N NH1 . ARG A 184 ? 0.70470 0.69370 0.74010 0.07320  -0.05200 -0.08780 184 ARG A NH1 
2859 N NH2 . ARG A 184 ? 0.74260 0.70430 0.77530 0.08420  -0.05800 -0.08000 184 ARG A NH2 
2873 N N   . VAL A 185 ? 0.70460 0.76930 0.87330 0.11680  -0.07290 -0.14380 185 VAL A N   
2874 C CA  . VAL A 185 ? 0.72120 0.80900 0.91110 0.12090  -0.07820 -0.14910 185 VAL A CA  
2875 C C   . VAL A 185 ? 0.74090 0.81880 0.91790 0.11800  -0.08840 -0.13540 185 VAL A C   
2876 O O   . VAL A 185 ? 0.76780 0.82120 0.93410 0.12230  -0.09710 -0.12450 185 VAL A O   
2877 C CB  . VAL A 185 ? 0.73360 0.82540 0.95490 0.13560  -0.08450 -0.15950 185 VAL A CB  
2878 C CG1 . VAL A 185 ? 0.75110 0.87110 0.99720 0.13990  -0.08950 -0.16510 185 VAL A CG1 
2879 C CG2 . VAL A 185 ? 0.75310 0.85270 0.98550 0.13870  -0.07470 -0.17600 185 VAL A CG2 
2889 N N   . LEU A 186 ? 0.76830 0.86630 0.94630 0.11030  -0.08750 -0.13600 186 LEU A N   
2890 C CA  . LEU A 186 ? 0.81410 0.90670 0.98140 0.10650  -0.09780 -0.12680 186 LEU A CA  
2891 C C   . LEU A 186 ? 0.80420 0.92280 0.99910 0.11060  -0.10630 -0.13240 186 LEU A C   
2892 O O   . LEU A 186 ? 0.80820 0.95280 1.02940 0.11380  -0.10100 -0.14350 186 LEU A O   
2893 C CB  . LEU A 186 ? 0.79350 0.88420 0.93950 0.09230  -0.09100 -0.12220 186 LEU A CB  
2894 C CG  . LEU A 186 ? 0.82020 0.89050 0.94190 0.08740  -0.08110 -0.11700 186 LEU A CG  
2895 C CD1 . LEU A 186 ? 0.83900 0.91490 0.95030 0.07410  -0.07300 -0.11470 186 LEU A CD1 
2896 C CD2 . LEU A 186 ? 0.82230 0.86280 0.92200 0.09120  -0.08780 -0.10660 186 LEU A CD2 
2908 N N   . ASN A 187 ? 0.82490 0.93850 1.01380 0.11050  -0.11970 -0.12520 187 ASN A N   
2909 C CA  . ASN A 187 ? 0.84060 0.97920 1.05510 0.11320  -0.13020 -0.12910 187 ASN A CA  
2910 C C   . ASN A 187 ? 0.82900 0.96520 1.02680 0.10330  -0.13890 -0.12370 187 ASN A C   
2911 O O   . ASN A 187 ? 0.82080 0.93400 0.99270 0.10410  -0.14690 -0.11490 187 ASN A O   
2912 C CB  . ASN A 187 ? 0.80070 0.93680 1.03370 0.12900  -0.14320 -0.12710 187 ASN A CB  
2913 C CG  . ASN A 187 ? 0.79780 0.96340 1.06240 0.13330  -0.15430 -0.13160 187 ASN A CG  
2914 O OD1 . ASN A 187 ? 0.82920 0.99200 1.10120 0.14260  -0.17020 -0.12510 187 ASN A OD1 
2915 N ND2 . ASN A 187 ? 0.79700 0.99300 1.08160 0.12650  -0.14610 -0.14150 187 ASN A ND2 
2922 N N   . VAL A 188 ? 0.83640 0.99690 1.04920 0.09360  -0.13690 -0.12930 188 VAL A N   
2923 C CA  . VAL A 188 ? 0.79200 0.95190 0.99400 0.08270  -0.14520 -0.12720 188 VAL A CA  
2924 C C   . VAL A 188 ? 0.82580 1.00970 1.05400 0.08660  -0.16110 -0.13010 188 VAL A C   
2925 O O   . VAL A 188 ? 0.85410 1.06850 1.11630 0.08760  -0.15840 -0.13660 188 VAL A O   
2926 C CB  . VAL A 188 ? 0.80640 0.97480 1.00920 0.06720  -0.13290 -0.12970 188 VAL A CB  
2927 C CG1 . VAL A 188 ? 0.80790 0.96630 0.99580 0.05600  -0.14140 -0.12850 188 VAL A CG1 
2928 C CG2 . VAL A 188 ? 0.78500 0.93720 0.96960 0.06530  -0.11660 -0.12710 188 VAL A CG2 
2938 N N   . VAL A 189 ? 0.83460 1.00740 1.04710 0.08880  -0.17750 -0.12520 189 VAL A N   
2939 C CA  . VAL A 189 ? 0.87960 1.07390 1.11410 0.09350  -0.19570 -0.12620 189 VAL A CA  
2940 C C   . VAL A 189 ? 0.88100 1.08140 1.10930 0.07960  -0.20460 -0.12990 189 VAL A C   
2941 O O   . VAL A 189 ? 0.86210 1.03990 1.05640 0.07470  -0.20910 -0.12750 189 VAL A O   
2942 C CB  . VAL A 189 ? 0.86020 1.04020 1.08270 0.10760  -0.21020 -0.11680 189 VAL A CB  
2943 C CG1 . VAL A 189 ? 0.85200 1.05800 1.10220 0.11410  -0.22960 -0.11690 189 VAL A CG1 
2944 C CG2 . VAL A 189 ? 0.91540 1.08190 1.14190 0.11990  -0.20080 -0.11310 189 VAL A CG2 
2954 N N   . CYS A 190 ? 0.86400 1.09570 1.12630 0.07290  -0.20700 -0.13650 190 CYS A N   
2955 C CA  . CYS A 190 ? 0.84580 1.08720 1.11120 0.05960  -0.21850 -0.14130 190 CYS A CA  
2956 C C   . CYS A 190 ? 0.83190 1.10150 1.12520 0.06570  -0.23830 -0.14270 190 CYS A C   
2957 O O   . CYS A 190 ? 0.83720 1.13410 1.16750 0.07290  -0.23630 -0.14420 190 CYS A O   
2958 C CB  . CYS A 190 ? 0.84620 1.10180 1.13110 0.04360  -0.20510 -0.14610 190 CYS A CB  
2959 S SG  . CYS A 190 ? 0.77220 1.03780 1.06670 0.02530  -0.21950 -0.15300 190 CYS A SG  
2964 N N   . LYS A 191 ? 0.84990 1.11460 1.12600 0.06330  -0.25760 -0.14300 191 LYS A N   
2965 C CA  . LYS A 191 ? 0.78780 1.07980 1.08820 0.06930  -0.27910 -0.14320 191 LYS A CA  
2966 C C   . LYS A 191 ? 0.81030 1.14050 1.15890 0.06050  -0.27950 -0.15070 191 LYS A C   
2967 O O   . LYS A 191 ? 0.77280 1.13220 1.15350 0.06810  -0.29330 -0.15050 191 LYS A O   
2968 C CB  . LYS A 191 ? 0.89050 1.17270 1.16030 0.06530  -0.29950 -0.14400 191 LYS A CB  
2969 C CG  . LYS A 191 ? 0.93660 1.18420 1.15680 0.07260  -0.29880 -0.13600 191 LYS A CG  
2970 C CD  . LYS A 191 ? 1.02010 1.26960 1.21620 0.07510  -0.32300 -0.13410 191 LYS A CD  
2971 C CE  . LYS A 191 ? 0.98750 1.23680 1.16980 0.05850  -0.33100 -0.14790 191 LYS A CE  
2972 N NZ  . LYS A 191 ? 0.97150 1.24120 1.15160 0.05890  -0.35850 -0.15050 191 LYS A NZ  
2986 N N   . THR A 192 ? 0.84120 1.17320 1.19740 0.04470  -0.26490 -0.15590 192 THR A N   
2987 C CA  . THR A 192 ? 0.85300 1.22220 1.25510 0.03400  -0.26340 -0.16120 192 THR A CA  
2988 C C   . THR A 192 ? 0.82080 1.20830 1.24950 0.03680  -0.24110 -0.16020 192 THR A C   
2989 O O   . THR A 192 ? 0.79940 1.22610 1.27220 0.03620  -0.24060 -0.16300 192 THR A O   
2990 C CB  . THR A 192 ? 0.82520 1.18760 1.22300 0.01220  -0.26400 -0.16670 192 THR A CB  
2991 O OG1 . THR A 192 ? 0.77440 1.13170 1.15810 0.00870  -0.28770 -0.17170 192 THR A OG1 
2992 C CG2 . THR A 192 ? 0.72690 1.12600 1.17290 -0.00110 -0.25700 -0.16910 192 THR A CG2 
3000 N N   . CYS A 193 ? 0.85940 1.22220 1.26290 0.03990  -0.22250 -0.15690 193 CYS A N   
3001 C CA  . CYS A 193 ? 0.89540 1.27510 1.31820 0.04150  -0.20070 -0.15730 193 CYS A CA  
3002 C C   . CYS A 193 ? 0.88440 1.25690 1.30270 0.06160  -0.19490 -0.15650 193 CYS A C   
3003 O O   . CYS A 193 ? 0.90890 1.28770 1.33250 0.06410  -0.17590 -0.15830 193 CYS A O   
3004 C CB  . CYS A 193 ? 0.93040 1.29170 1.33230 0.02680  -0.18310 -0.15450 193 CYS A CB  
3005 S SG  . CYS A 193 ? 0.99350 1.34620 1.39180 0.00370  -0.19180 -0.15510 193 CYS A SG  
3010 N N   . GLY A 194 ? 0.87230 1.23180 1.28120 0.07570  -0.21130 -0.15370 194 GLY A N   
3011 C CA  . GLY A 194 ? 0.91910 1.27180 1.33070 0.09490  -0.20790 -0.15270 194 GLY A CA  
3012 C C   . GLY A 194 ? 0.91860 1.23580 1.29400 0.09640  -0.19330 -0.14950 194 GLY A C   
3013 O O   . GLY A 194 ? 0.87710 1.16750 1.21720 0.08610  -0.19110 -0.14550 194 GLY A O   
3017 N N   . GLN A 195 ? 0.94140 1.25920 1.32780 0.10970  -0.18360 -0.15240 195 GLN A N   
3018 C CA  . GLN A 195 ? 0.90760 1.19460 1.26530 0.11290  -0.17100 -0.15030 195 GLN A CA  
3019 C C   . GLN A 195 ? 0.90310 1.20280 1.26420 0.10440  -0.14890 -0.15680 195 GLN A C   
3020 O O   . GLN A 195 ? 0.92600 1.26160 1.31670 0.09980  -0.14200 -0.16330 195 GLN A O   
3021 C CB  . GLN A 195 ? 0.87540 1.15240 1.24340 0.13250  -0.17520 -0.15010 195 GLN A CB  
3022 C CG  . GLN A 195 ? 0.93570 1.17930 1.27660 0.13900  -0.19020 -0.13760 195 GLN A CG  
3023 C CD  . GLN A 195 ? 1.00070 1.24860 1.36780 0.15730  -0.20500 -0.13440 195 GLN A CD  
3024 O OE1 . GLN A 195 ? 1.03890 1.31090 1.44520 0.16720  -0.20230 -0.14350 195 GLN A OE1 
3025 N NE2 . GLN A 195 ? 1.02060 1.24590 1.36670 0.16230  -0.22060 -0.12070 195 GLN A NE2 
3034 N N   . GLN A 196 ? 0.90000 1.17200 1.23030 0.10210  -0.13790 -0.15400 196 GLN A N   
3035 C CA  . GLN A 196 ? 0.87220 1.15470 1.20110 0.09500  -0.11770 -0.15870 196 GLN A CA  
3036 C C   . GLN A 196 ? 0.85100 1.10100 1.15100 0.09940  -0.11050 -0.15640 196 GLN A C   
3037 O O   . GLN A 196 ? 0.86940 1.09030 1.13730 0.09260  -0.11170 -0.14790 196 GLN A O   
3038 C CB  . GLN A 196 ? 0.90520 1.19500 1.22660 0.07580  -0.11220 -0.15420 196 GLN A CB  
3039 C CG  . GLN A 196 ? 0.89260 1.19340 1.20950 0.06720  -0.09200 -0.15520 196 GLN A CG  
3040 C CD  . GLN A 196 ? 0.96920 1.30180 1.31160 0.07630  -0.08070 -0.16610 196 GLN A CD  
3041 O OE1 . GLN A 196 ? 0.96000 1.28140 1.29810 0.08920  -0.07830 -0.17220 196 GLN A OE1 
3042 N NE2 . GLN A 196 ? 0.92340 1.29660 1.29360 0.06960  -0.07350 -0.16930 196 GLN A NE2 
3051 N N   . GLN A 197 ? 0.83360 1.08940 1.14660 0.11080  -0.10330 -0.16510 197 GLN A N   
3052 C CA  . GLN A 197 ? 0.82880 1.05650 1.11970 0.11510  -0.09700 -0.16460 197 GLN A CA  
3053 C C   . GLN A 197 ? 0.78420 1.01980 1.06140 0.10410  -0.07930 -0.16700 197 GLN A C   
3054 O O   . GLN A 197 ? 0.75260 1.02230 1.04690 0.09910  -0.06930 -0.17360 197 GLN A O   
3055 C CB  . GLN A 197 ? 0.82140 1.05000 1.13500 0.13240  -0.09880 -0.17450 197 GLN A CB  
3056 C CG  . GLN A 197 ? 0.84740 1.03870 1.14160 0.13860  -0.10030 -0.17050 197 GLN A CG  
3057 C CD  . GLN A 197 ? 0.84490 1.03830 1.16440 0.15370  -0.09860 -0.18380 197 GLN A CD  
3058 O OE1 . GLN A 197 ? 0.82860 1.00420 1.16010 0.16590  -0.11060 -0.18040 197 GLN A OE1 
3059 N NE2 . GLN A 197 ? 0.79890 1.01440 1.12720 0.15290  -0.08400 -0.19900 197 GLN A NE2 
3068 N N   . THR A 198 ? 0.82580 1.03180 1.07270 0.10040  -0.07560 -0.16050 198 THR A N   
3069 C CA  . THR A 198 ? 0.78520 0.99580 1.01660 0.09050  -0.06070 -0.16040 198 THR A CA  
3070 C C   . THR A 198 ? 0.77830 0.96520 0.99420 0.09640  -0.05720 -0.16240 198 THR A C   
3071 O O   . THR A 198 ? 0.76470 0.92180 0.97100 0.10290  -0.06620 -0.15710 198 THR A O   
3072 C CB  . THR A 198 ? 0.85660 1.05630 1.06640 0.07550  -0.05970 -0.14780 198 THR A CB  
3073 O OG1 . THR A 198 ? 0.91430 1.12590 1.13760 0.07080  -0.06830 -0.14520 198 THR A OG1 
3074 C CG2 . THR A 198 ? 0.89940 1.11620 1.10330 0.06460  -0.04450 -0.14650 198 THR A CG2 
3082 N N   . THR A 199 ? 0.73600 0.93800 0.94970 0.09350  -0.04430 -0.16960 199 THR A N   
3083 C CA  . THR A 199 ? 0.69620 0.88090 0.89820 0.09790  -0.04050 -0.17420 199 THR A CA  
3084 C C   . THR A 199 ? 0.71070 0.89210 0.88730 0.08550  -0.03100 -0.16610 199 THR A C   
3085 O O   . THR A 199 ? 0.70270 0.91010 0.87920 0.07620  -0.02220 -0.16460 199 THR A O   
3086 C CB  . THR A 199 ? 0.70220 0.90990 0.92650 0.10770  -0.03490 -0.19390 199 THR A CB  
3087 O OG1 . THR A 199 ? 0.75420 0.95660 1.00320 0.12160  -0.04540 -0.20030 199 THR A OG1 
3088 C CG2 . THR A 199 ? 0.71790 0.91280 0.92920 0.10870  -0.02960 -0.20040 199 THR A CG2 
3096 N N   . LEU A 200 ? 0.71330 0.86400 0.87030 0.08540  -0.03300 -0.15960 200 LEU A N   
3097 C CA  . LEU A 200 ? 0.71720 0.86210 0.85150 0.07520  -0.02550 -0.15090 200 LEU A CA  
3098 C C   . LEU A 200 ? 0.71270 0.84810 0.84130 0.07910  -0.02280 -0.15790 200 LEU A C   
3099 O O   . LEU A 200 ? 0.69180 0.80960 0.82850 0.08860  -0.02930 -0.16360 200 LEU A O   
3100 C CB  . LEU A 200 ? 0.65200 0.76900 0.76710 0.06950  -0.03040 -0.13460 200 LEU A CB  
3101 C CG  . LEU A 200 ? 0.77420 0.89600 0.89430 0.06520  -0.03550 -0.12900 200 LEU A CG  
3102 C CD1 . LEU A 200 ? 0.71270 0.80360 0.81430 0.06360  -0.04240 -0.11760 200 LEU A CD1 
3103 C CD2 . LEU A 200 ? 0.77460 0.92190 0.89780 0.05370  -0.02690 -0.12580 200 LEU A CD2 
3115 N N   . LYS A 201 ? 0.69590 0.84330 0.81180 0.07130  -0.01400 -0.15670 201 LYS A N   
3116 C CA  . LYS A 201 ? 0.74980 0.89330 0.86050 0.07320  -0.01160 -0.16480 201 LYS A CA  
3117 C C   . LYS A 201 ? 0.71290 0.84700 0.80140 0.06360  -0.00790 -0.15090 201 LYS A C   
3118 O O   . LYS A 201 ? 0.75550 0.89380 0.83480 0.05520  -0.00480 -0.13750 201 LYS A O   
3119 C CB  . LYS A 201 ? 0.73480 0.91370 0.85610 0.07530  -0.00430 -0.18350 201 LYS A CB  
3120 C CG  . LYS A 201 ? 0.81080 1.00510 0.95800 0.08560  -0.00620 -0.19890 201 LYS A CG  
3121 C CD  . LYS A 201 ? 0.82390 1.00670 0.98590 0.09730  -0.01070 -0.21710 201 LYS A CD  
3122 C CE  . LYS A 201 ? 0.93490 1.14350 1.12410 0.10780  -0.00920 -0.23710 201 LYS A CE  
3123 N NZ  . LYS A 201 ? 1.00630 1.25980 1.19430 0.10350  0.00330  -0.24850 201 LYS A NZ  
3137 N N   . GLY A 202 ? 0.71920 0.84010 0.80200 0.06490  -0.00880 -0.15420 202 GLY A N   
3138 C CA  . GLY A 202 ? 0.65230 0.76810 0.71720 0.05670  -0.00550 -0.14220 202 GLY A CA  
3139 C C   . GLY A 202 ? 0.64030 0.72940 0.69410 0.05370  -0.00820 -0.12370 202 GLY A C   
3140 O O   . GLY A 202 ? 0.67730 0.74230 0.73330 0.05910  -0.01430 -0.12080 202 GLY A O   
3144 N N   . VAL A 203 ? 0.62290 0.71740 0.66480 0.04520  -0.00350 -0.11080 203 VAL A N   
3145 C CA  . VAL A 203 ? 0.61680 0.68710 0.64850 0.04260  -0.00490 -0.09520 203 VAL A CA  
3146 C C   . VAL A 203 ? 0.64940 0.70990 0.68540 0.04520  -0.00950 -0.09400 203 VAL A C   
3147 O O   . VAL A 203 ? 0.63740 0.67320 0.66780 0.04870  -0.01410 -0.08890 203 VAL A O   
3148 C CB  . VAL A 203 ? 0.66780 0.74790 0.69100 0.03360  0.00070  -0.08240 203 VAL A CB  
3149 C CG1 . VAL A 203 ? 0.64690 0.70220 0.66250 0.03200  -0.00050 -0.06910 203 VAL A CG1 
3150 C CG2 . VAL A 203 ? 0.66850 0.75800 0.68600 0.03130  0.00340  -0.08210 203 VAL A CG2 
3160 N N   . GLU A 204 ? 0.63310 0.71530 0.67920 0.04330  -0.00840 -0.09850 204 GLU A N   
3161 C CA  . GLU A 204 ? 0.62430 0.70100 0.67670 0.04480  -0.01390 -0.09810 204 GLU A CA  
3162 C C   . GLU A 204 ? 0.64560 0.70700 0.70330 0.05490  -0.02200 -0.10460 204 GLU A C   
3163 O O   . GLU A 204 ? 0.64410 0.69680 0.70320 0.05690  -0.02860 -0.10250 204 GLU A O   
3164 C CB  . GLU A 204 ? 0.62130 0.72880 0.68810 0.04080  -0.01090 -0.10270 204 GLU A CB  
3167 N N   . ALA A 205 ? 0.60250 0.66060 0.66430 0.06110  -0.02260 -0.11210 205 ALA A N   
3168 C CA  . ALA A 205 ? 0.66710 0.71000 0.73730 0.07080  -0.03070 -0.11630 205 ALA A CA  
3169 C C   . ALA A 205 ? 0.64830 0.66080 0.70480 0.07230  -0.03450 -0.10500 205 ALA A C   
3170 O O   . ALA A 205 ? 0.71850 0.71700 0.77910 0.07930  -0.04220 -0.10330 205 ALA A O   
3171 C CB  . ALA A 205 ? 0.64710 0.69930 0.73250 0.07680  -0.03000 -0.13090 205 ALA A CB  
3177 N N   . VAL A 206 ? 0.61950 0.62320 0.66050 0.06630  -0.02920 -0.09610 206 VAL A N   
3178 C CA  . VAL A 206 ? 0.65140 0.62990 0.67990 0.06760  -0.03070 -0.08540 206 VAL A CA  
3179 C C   . VAL A 206 ? 0.67090 0.64020 0.68300 0.06360  -0.02940 -0.07540 206 VAL A C   
3180 O O   . VAL A 206 ? 0.64900 0.60000 0.64890 0.06490  -0.02950 -0.06660 206 VAL A O   
3181 C CB  . VAL A 206 ? 0.66540 0.63990 0.69220 0.06530  -0.02610 -0.08400 206 VAL A CB  
3182 C CG1 . VAL A 206 ? 0.66570 0.65020 0.70940 0.06870  -0.02750 -0.09760 206 VAL A CG1 
3183 C CG2 . VAL A 206 ? 0.68500 0.66940 0.70260 0.05750  -0.01870 -0.07930 206 VAL A CG2 
3193 N N   . MET A 207 ? 0.67420 0.65600 0.68690 0.05870  -0.02800 -0.07680 207 MET A N   
3194 C CA  . MET A 207 ? 0.66320 0.63540 0.66330 0.05450  -0.02700 -0.06980 207 MET A CA  
3195 C C   . MET A 207 ? 0.65200 0.62840 0.65560 0.05450  -0.03370 -0.07360 207 MET A C   
3196 O O   . MET A 207 ? 0.67240 0.66760 0.69100 0.05360  -0.03550 -0.08030 207 MET A O   
3197 C CB  . MET A 207 ? 0.62590 0.60670 0.62550 0.04670  -0.01940 -0.06590 207 MET A CB  
3198 C CG  . MET A 207 ? 0.72370 0.69300 0.71370 0.04600  -0.01380 -0.05790 207 MET A CG  
3199 S SD  . MET A 207 ? 0.73920 0.72620 0.73390 0.03850  -0.00650 -0.05340 207 MET A SD  
3200 C CE  . MET A 207 ? 0.72170 0.69490 0.71030 0.03440  -0.00390 -0.04390 207 MET A CE  
3210 N N   . TYR A 208 ? 0.66850 0.62920 0.65850 0.05540  -0.03750 -0.07020 208 TYR A N   
3211 C CA  . TYR A 208 ? 0.71270 0.67670 0.70430 0.05390  -0.04490 -0.07420 208 TYR A CA  
3212 C C   . TYR A 208 ? 0.70440 0.65370 0.68090 0.05030  -0.04380 -0.07190 208 TYR A C   
3213 O O   . TYR A 208 ? 0.67180 0.60550 0.63240 0.05330  -0.04050 -0.06710 208 TYR A O   
3214 C CB  . TYR A 208 ? 0.68690 0.64930 0.67870 0.06160  -0.05520 -0.07600 208 TYR A CB  
3215 C CG  . TYR A 208 ? 0.68950 0.65890 0.68470 0.05960  -0.06440 -0.08110 208 TYR A CG  
3216 C CD1 . TYR A 208 ? 0.70510 0.69570 0.72180 0.05630  -0.06660 -0.08730 208 TYR A CD1 
3217 C CD2 . TYR A 208 ? 0.76080 0.71780 0.73800 0.06050  -0.07070 -0.08030 208 TYR A CD2 
3218 C CE1 . TYR A 208 ? 0.73840 0.73680 0.76110 0.05350  -0.07570 -0.09200 208 TYR A CE1 
3219 C CE2 . TYR A 208 ? 0.77830 0.74260 0.75900 0.05800  -0.08050 -0.08630 208 TYR A CE2 
3220 C CZ  . TYR A 208 ? 0.78340 0.76810 0.78820 0.05420  -0.08340 -0.09180 208 TYR A CZ  
3221 O OH  . TYR A 208 ? 0.80320 0.79680 0.81460 0.05070  -0.09390 -0.09790 208 TYR A OH  
3231 N N   . MET A 209 ? 0.66770 0.62260 0.65110 0.04390  -0.04650 -0.07600 209 MET A N   
3232 C CA  . MET A 209 ? 0.69670 0.63770 0.67050 0.03990  -0.04610 -0.07690 209 MET A CA  
3233 C C   . MET A 209 ? 0.76130 0.70240 0.73250 0.03990  -0.05750 -0.08470 209 MET A C   
3234 O O   . MET A 209 ? 0.73020 0.68590 0.71850 0.03490  -0.06300 -0.08910 209 MET A O   
3235 C CB  . MET A 209 ? 0.70810 0.65430 0.69580 0.03080  -0.04000 -0.07430 209 MET A CB  
3236 C CG  . MET A 209 ? 0.84990 0.77830 0.83170 0.02720  -0.03780 -0.07440 209 MET A CG  
3237 S SD  . MET A 209 ? 0.90590 0.81180 0.86210 0.03560  -0.03470 -0.07460 209 MET A SD  
3238 C CE  . MET A 209 ? 0.97430 0.86360 0.93170 0.03080  -0.03490 -0.08100 209 MET A CE  
3248 N N   . GLY A 210 ? 0.75540 0.68270 0.70540 0.04510  -0.06120 -0.08620 210 GLY A N   
3249 C CA  . GLY A 210 ? 0.78740 0.71550 0.73120 0.04510  -0.07320 -0.09420 210 GLY A CA  
3250 C C   . GLY A 210 ? 0.81630 0.73520 0.73390 0.05300  -0.07720 -0.09300 210 GLY A C   
3251 O O   . GLY A 210 ? 0.85650 0.77040 0.75930 0.05270  -0.08360 -0.10050 210 GLY A O   
3255 N N   . THR A 211 ? 0.76910 0.68650 0.68100 0.05980  -0.07370 -0.08340 211 THR A N   
3256 C CA  . THR A 211 ? 0.83620 0.74690 0.72430 0.06690  -0.07670 -0.07830 211 THR A CA  
3257 C C   . THR A 211 ? 0.78810 0.69110 0.67180 0.07070  -0.06610 -0.06710 211 THR A C   
3258 O O   . THR A 211 ? 0.74020 0.64660 0.64170 0.06980  -0.06110 -0.06360 211 THR A O   
3259 C CB  . THR A 211 ? 0.85250 0.77360 0.74280 0.07150  -0.09050 -0.07640 211 THR A CB  
3260 O OG1 . THR A 211 ? 0.92100 0.83640 0.78830 0.07820  -0.09260 -0.06720 211 THR A OG1 
3261 C CG2 . THR A 211 ? 0.85550 0.78640 0.77220 0.07320  -0.09100 -0.07270 211 THR A CG2 
3269 N N   . LEU A 212 ? 0.76180 0.65610 0.62180 0.07470  -0.06260 -0.06200 212 LEU A N   
3270 C CA  . LEU A 212 ? 0.77010 0.65780 0.62640 0.07760  -0.05260 -0.05040 212 LEU A CA  
3271 C C   . LEU A 212 ? 0.76270 0.65170 0.61910 0.08290  -0.05820 -0.03850 212 LEU A C   
3272 O O   . LEU A 212 ? 0.78800 0.67280 0.65160 0.08400  -0.05180 -0.02920 212 LEU A O   
3273 C CB  . LEU A 212 ? 0.76740 0.64710 0.60030 0.07910  -0.04400 -0.04990 212 LEU A CB  
3274 C CG  . LEU A 212 ? 0.73780 0.61260 0.57050 0.07530  -0.03830 -0.06170 212 LEU A CG  
3275 C CD1 . LEU A 212 ? 0.76730 0.63620 0.57570 0.07910  -0.03070 -0.06310 212 LEU A CD1 
3276 C CD2 . LEU A 212 ? 0.76400 0.63750 0.61860 0.07120  -0.03000 -0.05980 212 LEU A CD2 
3288 N N   . SER A 213 ? 0.81830 0.71300 0.66930 0.08610  -0.07090 -0.03820 213 SER A N   
3289 C CA  . SER A 213 ? 0.79390 0.68850 0.64420 0.09180  -0.07750 -0.02460 213 SER A CA  
3290 C C   . SER A 213 ? 0.78390 0.68290 0.66460 0.09340  -0.08310 -0.02500 213 SER A C   
3291 O O   . SER A 213 ? 0.75040 0.65950 0.64460 0.09280  -0.09130 -0.03450 213 SER A O   
3292 C CB  . SER A 213 ? 0.83570 0.73620 0.66500 0.09520  -0.08950 -0.02260 213 SER A CB  
3293 O OG  . SER A 213 ? 0.80890 0.71040 0.64310 0.10100  -0.09850 -0.00810 213 SER A OG  
3299 N N   . TYR A 214 ? 0.84200 0.73410 0.73480 0.09540  -0.07870 -0.01560 214 TYR A N   
3300 C CA  . TYR A 214 ? 0.78070 0.67610 0.70270 0.09830  -0.08390 -0.01760 214 TYR A CA  
3301 C C   . TYR A 214 ? 0.81380 0.71370 0.74090 0.10500  -0.09890 -0.01220 214 TYR A C   
3302 O O   . TYR A 214 ? 0.83550 0.74450 0.78610 0.10780  -0.10600 -0.01980 214 TYR A O   
3303 C CB  . TYR A 214 ? 0.75630 0.64150 0.68990 0.09860  -0.07680 -0.00980 214 TYR A CB  
3304 C CG  . TYR A 214 ? 0.76610 0.65450 0.73070 0.10050  -0.07870 -0.01750 214 TYR A CG  
3305 C CD1 . TYR A 214 ? 0.75750 0.66020 0.73670 0.09930  -0.07980 -0.03260 214 TYR A CD1 
3306 C CD2 . TYR A 214 ? 0.75160 0.62970 0.73200 0.10330  -0.07880 -0.01030 214 TYR A CD2 
3307 C CE1 . TYR A 214 ? 0.74790 0.65650 0.75400 0.10170  -0.08040 -0.04150 214 TYR A CE1 
3308 C CE2 . TYR A 214 ? 0.74960 0.63060 0.75830 0.10570  -0.08050 -0.02050 214 TYR A CE2 
3309 C CZ  . TYR A 214 ? 0.78880 0.68610 0.80910 0.10530  -0.08080 -0.03670 214 TYR A CZ  
3310 O OH  . TYR A 214 ? 0.78640 0.68960 0.83360 0.10830  -0.08140 -0.04870 214 TYR A OH  
3320 N N   . GLU A 215 ? 0.87750 0.77320 0.78310 0.10800  -0.10390 0.00150  215 GLU A N   
3321 C CA  . GLU A 215 ? 0.89140 0.79240 0.80050 0.11470  -0.11960 0.00930  215 GLU A CA  
3322 C C   . GLU A 215 ? 0.88260 0.79920 0.79220 0.11390  -0.12930 -0.00420 215 GLU A C   
3323 O O   . GLU A 215 ? 0.87490 0.80070 0.80750 0.11850  -0.14030 -0.00700 215 GLU A O   
3324 C CB  . GLU A 215 ? 0.90560 0.80180 0.78710 0.11700  -0.12220 0.02830  215 GLU A CB  
3325 C CG  . GLU A 215 ? 0.98580 0.86780 0.86910 0.11680  -0.11300 0.04440  215 GLU A CG  
3326 C CD  . GLU A 215 ? 1.13770 1.01150 1.05780 0.12030  -0.11580 0.04670  215 GLU A CD  
3327 O OE1 . GLU A 215 ? 1.11770 0.99220 1.05320 0.12710  -0.12910 0.05430  215 GLU A OE1 
3328 O OE2 . GLU A 215 ? 1.07790 0.94490 1.01220 0.11660  -0.10530 0.04020  215 GLU A OE2 
3335 N N   . GLN A 216 ? 0.86860 0.78850 0.75560 0.10810  -0.12560 -0.01340 216 GLN A N   
3336 C CA  . GLN A 216 ? 0.91250 0.84640 0.80240 0.10550  -0.13480 -0.02730 216 GLN A CA  
3337 C C   . GLN A 216 ? 0.90150 0.84430 0.82540 0.10360  -0.13360 -0.03920 216 GLN A C   
3338 O O   . GLN A 216 ? 0.87630 0.83400 0.81570 0.10440  -0.14460 -0.04590 216 GLN A O   
3339 C CB  . GLN A 216 ? 0.94030 0.87250 0.80450 0.09890  -0.12910 -0.03730 216 GLN A CB  
3340 C CG  . GLN A 216 ? 0.97840 0.92370 0.84020 0.09570  -0.14130 -0.05020 216 GLN A CG  
3341 C CD  . GLN A 216 ? 1.06450 1.02020 0.91760 0.10160  -0.15890 -0.04250 216 GLN A CD  
3342 O OE1 . GLN A 216 ? 1.07590 1.02750 0.90720 0.10660  -0.16050 -0.02790 216 GLN A OE1 
3343 N NE2 . GLN A 216 ? 1.02860 0.99980 0.89980 0.10090  -0.17230 -0.05080 216 GLN A NE2 
3352 N N   . PHE A 217 ? 0.89090 0.82740 0.82660 0.10080  -0.12030 -0.04180 217 PHE A N   
3353 C CA  . PHE A 217 ? 0.83440 0.78220 0.80050 0.09940  -0.11790 -0.05230 217 PHE A CA  
3354 C C   . PHE A 217 ? 0.81950 0.77520 0.81110 0.10800  -0.12830 -0.05000 217 PHE A C   
3355 O O   . PHE A 217 ? 0.81980 0.79280 0.83440 0.10850  -0.13310 -0.05950 217 PHE A O   
3356 C CB  . PHE A 217 ? 0.77770 0.71800 0.74870 0.09590  -0.10280 -0.05360 217 PHE A CB  
3357 C CG  . PHE A 217 ? 0.82050 0.77510 0.81300 0.09100  -0.09700 -0.06570 217 PHE A CG  
3358 C CD1 . PHE A 217 ? 0.80250 0.76920 0.79740 0.08450  -0.09850 -0.07420 217 PHE A CD1 
3359 C CD2 . PHE A 217 ? 0.78390 0.74070 0.79420 0.09240  -0.09000 -0.06840 217 PHE A CD2 
3360 C CE1 . PHE A 217 ? 0.84620 0.82830 0.86080 0.07920  -0.09240 -0.08250 217 PHE A CE1 
3361 C CE2 . PHE A 217 ? 0.73030 0.70370 0.75750 0.08790  -0.08390 -0.07870 217 PHE A CE2 
3362 C CZ  . PHE A 217 ? 0.71370 0.70030 0.74290 0.08120  -0.08460 -0.08440 217 PHE A CZ  
3372 N N   . LYS A 218 ? 0.76620 0.70990 0.75650 0.11510  -0.13180 -0.03670 218 LYS A N   
3373 C CA  . LYS A 218 ? 0.79330 0.74160 0.81060 0.12470  -0.14250 -0.03340 218 LYS A CA  
3374 C C   . LYS A 218 ? 0.85480 0.81680 0.87200 0.12850  -0.15900 -0.03150 218 LYS A C   
3375 O O   . LYS A 218 ? 0.85310 0.82910 0.89920 0.13430  -0.16740 -0.03670 218 LYS A O   
3376 C CB  . LYS A 218 ? 0.83170 0.76120 0.84870 0.13040  -0.14280 -0.01740 218 LYS A CB  
3377 C CG  . LYS A 218 ? 0.80420 0.72190 0.82930 0.12750  -0.12920 -0.02050 218 LYS A CG  
3378 C CD  . LYS A 218 ? 0.85080 0.74850 0.87080 0.13020  -0.12890 -0.00240 218 LYS A CD  
3379 C CE  . LYS A 218 ? 0.86020 0.74720 0.88950 0.12630  -0.11650 -0.00650 218 LYS A CE  
3380 N NZ  . LYS A 218 ? 0.93230 0.80050 0.95490 0.12630  -0.11480 0.01240  218 LYS A NZ  
3394 N N   . LYS A 219 ? 0.85930 0.81950 0.84490 0.12550  -0.16390 -0.02500 219 LYS A N   
3395 C CA  . LYS A 219 ? 0.92020 0.89510 0.90310 0.12850  -0.18100 -0.02340 219 LYS A CA  
3396 C C   . LYS A 219 ? 0.91940 0.91330 0.91510 0.12230  -0.18330 -0.04130 219 LYS A C   
3397 O O   . LYS A 219 ? 0.90240 0.91410 0.92010 0.12630  -0.19620 -0.04440 219 LYS A O   
3398 C CB  . LYS A 219 ? 0.94880 0.91810 0.89120 0.12680  -0.18530 -0.01300 219 LYS A CB  
3399 C CG  . LYS A 219 ? 1.04280 0.99360 0.96850 0.12980  -0.17860 0.00540  219 LYS A CG  
3400 C CD  . LYS A 219 ? 1.21250 1.16520 1.10490 0.13210  -0.18840 0.02070  219 LYS A CD  
3401 C CE  . LYS A 219 ? 1.28060 1.21740 1.14930 0.13120  -0.17680 0.03660  219 LYS A CE  
3402 N NZ  . LYS A 219 ? 1.40980 1.35170 1.23500 0.12840  -0.17730 0.04010  219 LYS A NZ  
3416 N N   . GLY A 220 ? 0.89060 0.88190 0.87550 0.11240  -0.17120 -0.05220 220 GLY A N   
3417 C CA  . GLY A 220 ? 0.88980 0.89760 0.88850 0.10470  -0.17220 -0.06730 220 GLY A CA  
3418 C C   . GLY A 220 ? 0.90220 0.90360 0.87540 0.09450  -0.16720 -0.07460 220 GLY A C   
3419 O O   . GLY A 220 ? 0.92300 0.91510 0.86510 0.09490  -0.17050 -0.07010 220 GLY A O   
3423 N N   . VAL A 221 ? 0.94290 0.95000 0.92980 0.08560  -0.15900 -0.08580 221 VAL A N   
3424 C CA  . VAL A 221 ? 0.90270 0.90240 0.87230 0.07580  -0.15430 -0.09390 221 VAL A CA  
3425 C C   . VAL A 221 ? 0.92960 0.94700 0.92120 0.06740  -0.16090 -0.10550 221 VAL A C   
3426 O O   . VAL A 221 ? 0.92310 0.95800 0.94580 0.06700  -0.16070 -0.10760 221 VAL A O   
3427 C CB  . VAL A 221 ? 0.92150 0.90630 0.88600 0.07170  -0.13580 -0.09280 221 VAL A CB  
3428 C CG1 . VAL A 221 ? 0.91890 0.88970 0.87020 0.07960  -0.12930 -0.08080 221 VAL A CG1 
3429 C CG2 . VAL A 221 ? 0.89890 0.89630 0.89360 0.06670  -0.12790 -0.09740 221 VAL A CG2 
3439 N N   . GLN A 222 ? 0.95250 0.96620 0.92910 0.06040  -0.16650 -0.11390 222 GLN A N   
3440 C CA  . GLN A 222 ? 0.95900 0.98820 0.95680 0.05090  -0.17480 -0.12510 222 GLN A CA  
3441 C C   . GLN A 222 ? 0.91120 0.93740 0.92540 0.04030  -0.16100 -0.12900 222 GLN A C   
3442 O O   . GLN A 222 ? 0.91610 0.92280 0.91360 0.03760  -0.14990 -0.12870 222 GLN A O   
3443 C CB  . GLN A 222 ? 1.04890 1.07470 1.02460 0.04740  -0.18800 -0.13430 222 GLN A CB  
3444 C CG  . GLN A 222 ? 1.05120 1.07980 1.00340 0.05750  -0.20130 -0.12810 222 GLN A CG  
3445 C CD  . GLN A 222 ? 1.11760 1.16340 1.09210 0.06650  -0.20890 -0.11800 222 GLN A CD  
3446 O OE1 . GLN A 222 ? 1.07060 1.13730 1.07650 0.06390  -0.21700 -0.12250 222 GLN A OE1 
3447 N NE2 . GLN A 222 ? 1.07690 1.11390 1.03770 0.07720  -0.20630 -0.10410 222 GLN A NE2 
3456 N N   . ILE A 223 ? 0.88690 0.93430 0.93500 0.03460  -0.16170 -0.13160 223 ILE A N   
3457 C CA  . ILE A 223 ? 0.89160 0.94040 0.95780 0.02320  -0.14990 -0.13300 223 ILE A CA  
3458 C C   . ILE A 223 ? 0.88860 0.95900 0.98470 0.01290  -0.15900 -0.14000 223 ILE A C   
3459 O O   . ILE A 223 ? 0.90950 1.00060 1.02060 0.01630  -0.17150 -0.14230 223 ILE A O   
3460 C CB  . ILE A 223 ? 0.86720 0.92310 0.94620 0.02640  -0.13470 -0.12510 223 ILE A CB  
3461 C CG1 . ILE A 223 ? 0.88090 0.96680 0.99090 0.02970  -0.13840 -0.12560 223 ILE A CG1 
3462 C CG2 . ILE A 223 ? 0.84780 0.88500 0.90150 0.03720  -0.12820 -0.11810 223 ILE A CG2 
3463 C CD1 . ILE A 223 ? 0.81970 0.91660 0.94350 0.03220  -0.12350 -0.12140 223 ILE A CD1 
3475 N N   . PRO A 224 ? 0.91450 0.98140 1.02290 -0.00030 -0.15320 -0.14240 224 PRO A N   
3476 C CA  . PRO A 224 ? 0.94580 1.03360 1.08630 -0.01220 -0.16150 -0.14800 224 PRO A CA  
3477 C C   . PRO A 224 ? 0.90490 1.02470 1.07820 -0.01230 -0.15580 -0.14240 224 PRO A C   
3478 O O   . PRO A 224 ? 0.89950 1.02250 1.07440 -0.00890 -0.14090 -0.13480 224 PRO A O   
3479 C CB  . PRO A 224 ? 0.97380 1.04470 1.11840 -0.02590 -0.15460 -0.14910 224 PRO A CB  
3480 C CG  . PRO A 224 ? 0.95330 0.99340 1.06430 -0.01940 -0.14570 -0.14680 224 PRO A CG  
3481 C CD  . PRO A 224 ? 0.94040 0.98390 1.03630 -0.00520 -0.14000 -0.13930 224 PRO A CD  
3489 N N   . CYS A 225 ? 0.89630 1.04210 1.09630 -0.01590 -0.16810 -0.14740 225 CYS A N   
3490 C CA  . CYS A 225 ? 0.85180 1.03280 1.08820 -0.01740 -0.16310 -0.14420 225 CYS A CA  
3491 C C   . CYS A 225 ? 0.90780 1.10390 1.17530 -0.03570 -0.16290 -0.14500 225 CYS A C   
3492 O O   . CYS A 225 ? 0.86500 1.04810 1.13120 -0.04580 -0.17350 -0.15150 225 CYS A O   
3493 C CB  . CYS A 225 ? 0.81310 1.01680 1.06250 -0.00630 -0.17680 -0.14780 225 CYS A CB  
3494 S SG  . CYS A 225 ? 0.88260 1.13380 1.18070 -0.00660 -0.17060 -0.14650 225 CYS A SG  
3499 N N   . THR A 226 ? 0.94340 1.16800 1.23970 -0.04040 -0.15060 -0.13870 226 THR A N   
3500 C CA  . THR A 226 ? 0.96210 1.20290 1.29030 -0.05910 -0.14810 -0.13580 226 THR A CA  
3501 C C   . THR A 226 ? 0.91120 1.16630 1.26310 -0.06670 -0.16750 -0.14490 226 THR A C   
3502 O O   . THR A 226 ? 0.85160 1.10360 1.22070 -0.08360 -0.17140 -0.14570 226 THR A O   
3503 C CB  . THR A 226 ? 0.95510 1.23200 1.31040 -0.06130 -0.13180 -0.12740 226 THR A CB  
3504 O OG1 . THR A 226 ? 0.90970 1.20940 1.30170 -0.07970 -0.13160 -0.12360 226 THR A OG1 
3505 C CG2 . THR A 226 ? 0.92140 1.22680 1.28820 -0.04590 -0.13380 -0.13220 226 THR A CG2 
3513 N N   . CYS A 227 ? 0.91030 1.18080 1.26480 -0.05480 -0.18060 -0.15140 227 CYS A N   
3514 C CA  . CYS A 227 ? 0.87820 1.16610 1.25590 -0.06150 -0.20070 -0.16000 227 CYS A CA  
3515 C C   . CYS A 227 ? 0.81090 1.06720 1.16440 -0.06730 -0.21610 -0.16970 227 CYS A C   
3516 O O   . CYS A 227 ? 0.76430 1.03170 1.13750 -0.07750 -0.23270 -0.17820 227 CYS A O   
3517 C CB  . CYS A 227 ? 0.90770 1.21990 1.29370 -0.04560 -0.21190 -0.16300 227 CYS A CB  
3518 S SG  . CYS A 227 ? 0.84470 1.12580 1.18180 -0.02580 -0.22240 -0.16530 227 CYS A SG  
3523 N N   . GLY A 228 ? 0.85660 1.07560 1.16870 -0.06110 -0.21090 -0.16970 228 GLY A N   
3524 C CA  . GLY A 228 ? 0.79460 0.98360 1.07960 -0.06420 -0.22330 -0.18070 228 GLY A CA  
3525 C C   . GLY A 228 ? 0.81750 0.99380 1.06360 -0.04760 -0.23310 -0.18450 228 GLY A C   
3526 O O   . GLY A 228 ? 0.74230 0.89000 0.95550 -0.04680 -0.23740 -0.19190 228 GLY A O   
3530 N N   . LYS A 229 ? 0.87150 1.06880 1.12160 -0.03400 -0.23650 -0.17920 229 LYS A N   
3531 C CA  . LYS A 229 ? 0.82680 1.01300 1.04200 -0.01810 -0.24530 -0.17880 229 LYS A CA  
3532 C C   . LYS A 229 ? 0.88760 1.04370 1.06820 -0.00960 -0.22850 -0.17150 229 LYS A C   
3533 O O   . LYS A 229 ? 0.88970 1.03500 1.07360 -0.01520 -0.21100 -0.16710 229 LYS A O   
3534 C CB  . LYS A 229 ? 0.87250 1.08800 1.10710 -0.00560 -0.25280 -0.17320 229 LYS A CB  
3535 C CG  . LYS A 229 ? 0.81960 1.06490 1.08200 -0.01030 -0.27420 -0.18030 229 LYS A CG  
3536 C CD  . LYS A 229 ? 0.87420 1.13240 1.13040 0.00620  -0.29000 -0.17600 229 LYS A CD  
3537 C CE  . LYS A 229 ? 0.74620 1.01920 1.00450 0.00140  -0.31600 -0.18510 229 LYS A CE  
3538 N NZ  . LYS A 229 ? 0.86010 1.10660 1.06850 0.00370  -0.32540 -0.18960 229 LYS A NZ  
3552 N N   . GLN A 230 ? 0.87920 1.02340 1.02710 0.00380  -0.23450 -0.16890 230 GLN A N   
3553 C CA  . GLN A 230 ? 0.94430 1.06380 1.06150 0.01340  -0.22020 -0.16070 230 GLN A CA  
3554 C C   . GLN A 230 ? 0.91100 1.04270 1.03680 0.02760  -0.21770 -0.15010 230 GLN A C   
3555 O O   . GLN A 230 ? 0.89630 1.03820 1.01950 0.03710  -0.23230 -0.14770 230 GLN A O   
3556 C CB  . GLN A 230 ? 0.95790 1.05450 1.03190 0.01750  -0.22730 -0.16450 230 GLN A CB  
3557 C CG  . GLN A 230 ? 1.00990 1.08520 1.07060 0.00620  -0.22350 -0.17530 230 GLN A CG  
3558 C CD  . GLN A 230 ? 1.08330 1.13020 1.11400 0.01090  -0.20700 -0.17050 230 GLN A CD  
3559 O OE1 . GLN A 230 ? 1.09590 1.12990 1.09140 0.01890  -0.20950 -0.17050 230 GLN A OE1 
3560 N NE2 . GLN A 230 ? 1.07480 1.11410 1.11970 0.00600  -0.19000 -0.16550 230 GLN A NE2 
3569 N N   . ALA A 231 ? 0.92860 1.05950 1.06530 0.02920  -0.19980 -0.14410 231 ALA A N   
3570 C CA  . ALA A 231 ? 0.91310 1.05290 1.05960 0.04270  -0.19580 -0.13660 231 ALA A CA  
3571 C C   . ALA A 231 ? 0.93300 1.04570 1.04500 0.05290  -0.19080 -0.12880 231 ALA A C   
3572 O O   . ALA A 231 ? 0.93070 1.01970 1.01310 0.04910  -0.18570 -0.12880 231 ALA A O   
3573 C CB  . ALA A 231 ? 0.87510 1.03000 1.04940 0.03940  -0.17910 -0.13590 231 ALA A CB  
3579 N N   . THR A 232 ? 0.88480 1.00170 1.00370 0.06620  -0.19230 -0.12210 232 THR A N   
3580 C CA  . THR A 232 ? 0.92050 1.01410 1.01300 0.07600  -0.18820 -0.11260 232 THR A CA  
3581 C C   . THR A 232 ? 0.87790 0.97070 0.98530 0.08060  -0.17260 -0.11040 232 THR A C   
3582 O O   . THR A 232 ? 0.83060 0.94280 0.96850 0.08680  -0.17360 -0.11240 232 THR A O   
3583 C CB  . THR A 232 ? 0.91080 1.00690 0.99810 0.08770  -0.20530 -0.10500 232 THR A CB  
3584 O OG1 . THR A 232 ? 0.98960 1.07920 1.04770 0.08380  -0.21710 -0.10580 232 THR A OG1 
3585 C CG2 . THR A 232 ? 0.93650 1.01440 1.01290 0.09910  -0.19980 -0.09310 232 THR A CG2 
3593 N N   . LYS A 233 ? 0.88430 0.95600 0.97080 0.07790  -0.15860 -0.10740 233 LYS A N   
3594 C CA  . LYS A 233 ? 0.89970 0.96840 0.99490 0.08170  -0.14450 -0.10580 233 LYS A CA  
3595 C C   . LYS A 233 ? 0.89750 0.94370 0.97310 0.09120  -0.14450 -0.09610 233 LYS A C   
3596 O O   . LYS A 233 ? 0.91450 0.94170 0.96000 0.08940  -0.14480 -0.09040 233 LYS A O   
3597 C CB  . LYS A 233 ? 0.82300 0.88750 0.91280 0.07070  -0.12890 -0.10850 233 LYS A CB  
3598 C CG  . LYS A 233 ? 0.89950 0.95350 0.98450 0.07370  -0.11490 -0.10530 233 LYS A CG  
3599 C CD  . LYS A 233 ? 0.83110 0.88210 0.90960 0.06270  -0.10140 -0.10580 233 LYS A CD  
3600 C CE  . LYS A 233 ? 0.81670 0.89500 0.92160 0.05530  -0.09630 -0.11130 233 LYS A CE  
3601 N NZ  . LYS A 233 ? 0.80350 0.87850 0.90240 0.04360  -0.08530 -0.10870 233 LYS A NZ  
3615 N N   . TYR A 234 ? 0.85000 0.89890 0.94410 0.10110  -0.14390 -0.09450 234 TYR A N   
3616 C CA  . TYR A 234 ? 0.85500 0.88250 0.93650 0.10940  -0.14420 -0.08420 234 TYR A CA  
3617 C C   . TYR A 234 ? 0.80110 0.82780 0.90120 0.11360  -0.13350 -0.08810 234 TYR A C   
3618 O O   . TYR A 234 ? 0.82070 0.86740 0.94540 0.11310  -0.12840 -0.09900 234 TYR A O   
3619 C CB  . TYR A 234 ? 0.83890 0.86660 0.92430 0.11960  -0.16120 -0.07540 234 TYR A CB  
3620 C CG  . TYR A 234 ? 0.87650 0.92430 1.00020 0.12850  -0.16860 -0.08070 234 TYR A CG  
3621 C CD1 . TYR A 234 ? 0.87470 0.91570 1.01830 0.13970  -0.16880 -0.07790 234 TYR A CD1 
3622 C CD2 . TYR A 234 ? 0.90390 0.97770 1.04660 0.12580  -0.17570 -0.08920 234 TYR A CD2 
3623 C CE1 . TYR A 234 ? 0.91730 0.97670 1.09840 0.14920  -0.17530 -0.08430 234 TYR A CE1 
3624 C CE2 . TYR A 234 ? 0.90470 0.99940 1.08490 0.13480  -0.18180 -0.09450 234 TYR A CE2 
3625 C CZ  . TYR A 234 ? 0.90340 0.99080 1.10260 0.14710  -0.18140 -0.09250 234 TYR A CZ  
3626 O OH  . TYR A 234 ? 0.87360 0.98200 1.11260 0.15750  -0.18710 -0.09930 234 TYR A OH  
3636 N N   . LEU A 235 ? 0.78260 0.78740 0.87060 0.11740  -0.13010 -0.07960 235 LEU A N   
3637 C CA  . LEU A 235 ? 0.80190 0.80210 0.90350 0.12020  -0.12020 -0.08420 235 LEU A CA  
3638 C C   . LEU A 235 ? 0.78660 0.79030 0.91850 0.13270  -0.12840 -0.08620 235 LEU A C   
3639 O O   . LEU A 235 ? 0.81850 0.80980 0.94990 0.14010  -0.13950 -0.07430 235 LEU A O   
3640 C CB  . LEU A 235 ? 0.78620 0.76160 0.86470 0.11770  -0.11350 -0.07410 235 LEU A CB  
3641 C CG  . LEU A 235 ? 0.77770 0.74570 0.86840 0.11960  -0.10490 -0.07840 235 LEU A CG  
3642 C CD1 . LEU A 235 ? 0.72650 0.71260 0.82570 0.11350  -0.09360 -0.09280 235 LEU A CD1 
3643 C CD2 . LEU A 235 ? 0.75950 0.70440 0.82810 0.11640  -0.09990 -0.06620 235 LEU A CD2 
3655 N N   . VAL A 236 ? 0.78270 0.80420 0.94140 0.13530  -0.12270 -0.10090 236 VAL A N   
3656 C CA  . VAL A 236 ? 0.78460 0.81030 0.97650 0.14820  -0.12910 -0.10650 236 VAL A CA  
3657 C C   . VAL A 236 ? 0.77030 0.77620 0.96800 0.15240  -0.12390 -0.10800 236 VAL A C   
3658 O O   . VAL A 236 ? 0.77160 0.76110 0.98310 0.16200  -0.13270 -0.10100 236 VAL A O   
3659 C CB  . VAL A 236 ? 0.78260 0.84130 1.00280 0.15000  -0.12540 -0.12380 236 VAL A CB  
3660 C CG1 . VAL A 236 ? 0.73930 0.80330 0.99690 0.16520  -0.13230 -0.13130 236 VAL A CG1 
3661 C CG2 . VAL A 236 ? 0.79940 0.87790 1.01630 0.14390  -0.13090 -0.12200 236 VAL A CG2 
3671 N N   . GLN A 237 ? 0.73730 0.74450 0.92600 0.14480  -0.11030 -0.11660 237 GLN A N   
3672 C CA  . GLN A 237 ? 0.80130 0.79240 0.99680 0.14730  -0.10540 -0.12100 237 GLN A CA  
3673 C C   . GLN A 237 ? 0.74000 0.72640 0.90940 0.13530  -0.09330 -0.12000 237 GLN A C   
3674 O O   . GLN A 237 ? 0.72150 0.72590 0.87960 0.12700  -0.08560 -0.12460 237 GLN A O   
3675 C CB  . GLN A 237 ? 0.75670 0.76470 0.98550 0.15550  -0.10260 -0.14220 237 GLN A CB  
3676 C CG  . GLN A 237 ? 0.82710 0.81580 1.06940 0.16020  -0.10140 -0.14880 237 GLN A CG  
3677 C CD  . GLN A 237 ? 1.00780 1.01750 1.27190 0.16400  -0.09330 -0.17460 237 GLN A CD  
3678 O OE1 . GLN A 237 ? 1.01560 1.05630 1.28590 0.16370  -0.08790 -0.18630 237 GLN A OE1 
3679 N NE2 . GLN A 237 ? 1.07140 1.06550 1.34770 0.16720  -0.09230 -0.18410 237 GLN A NE2 
3688 N N   . GLN A 238 ? 0.69770 0.66030 0.86020 0.13430  -0.09230 -0.11280 238 GLN A N   
3689 C CA  . GLN A 238 ? 0.74100 0.69820 0.88210 0.12410  -0.08190 -0.11090 238 GLN A CA  
3690 C C   . GLN A 238 ? 0.77010 0.71560 0.92520 0.12590  -0.07970 -0.11830 238 GLN A C   
3691 O O   . GLN A 238 ? 0.78890 0.71530 0.95970 0.13270  -0.08740 -0.11330 238 GLN A O   
3692 C CB  . GLN A 238 ? 0.74480 0.68440 0.85750 0.11850  -0.08270 -0.09100 238 GLN A CB  
3693 C CG  . GLN A 238 ? 0.75190 0.68760 0.84440 0.10850  -0.07200 -0.08810 238 GLN A CG  
3694 C CD  . GLN A 238 ? 0.75240 0.70930 0.83590 0.10120  -0.06400 -0.09600 238 GLN A CD  
3695 O OE1 . GLN A 238 ? 0.75080 0.72090 0.83380 0.10080  -0.06640 -0.09770 238 GLN A OE1 
3696 N NE2 . GLN A 238 ? 0.71390 0.67470 0.79170 0.09470  -0.05500 -0.09970 238 GLN A NE2 
3705 N N   . GLU A 239 ? 0.72340 0.68090 0.87380 0.11940  -0.07000 -0.12960 239 GLU A N   
3706 C CA  . GLU A 239 ? 0.73720 0.68600 0.89840 0.11900  -0.06780 -0.13890 239 GLU A CA  
3707 C C   . GLU A 239 ? 0.71900 0.67250 0.85740 0.10760  -0.05850 -0.13600 239 GLU A C   
3708 O O   . GLU A 239 ? 0.69870 0.67630 0.83130 0.10310  -0.05130 -0.14620 239 GLU A O   
3709 C CB  . GLU A 239 ? 0.77060 0.73660 0.95780 0.12610  -0.06730 -0.16340 239 GLU A CB  
3710 C CG  . GLU A 239 ? 0.91150 0.85720 1.12520 0.13340  -0.07380 -0.17130 239 GLU A CG  
3711 C CD  . GLU A 239 ? 1.13030 1.09440 1.36550 0.13850  -0.07060 -0.20010 239 GLU A CD  
3712 O OE1 . GLU A 239 ? 1.13600 1.11040 1.39460 0.14930  -0.07400 -0.21210 239 GLU A OE1 
3713 O OE2 . GLU A 239 ? 1.12410 1.09410 1.35310 0.13220  -0.06490 -0.21150 239 GLU A OE2 
3720 N N   . SER A 240 ? 0.65510 0.58760 0.78180 0.10300  -0.05860 -0.12080 240 SER A N   
3721 C CA  . SER A 240 ? 0.66010 0.59560 0.76800 0.09320  -0.05070 -0.11590 240 SER A CA  
3722 C C   . SER A 240 ? 0.70580 0.61640 0.80980 0.09070  -0.05230 -0.09990 240 SER A C   
3723 O O   . SER A 240 ? 0.68080 0.57370 0.78950 0.09550  -0.05860 -0.08830 240 SER A O   
3724 C CB  . SER A 240 ? 0.71600 0.66400 0.80160 0.08790  -0.04540 -0.10810 240 SER A CB  
3725 O OG  . SER A 240 ? 0.69310 0.62790 0.76820 0.09010  -0.04950 -0.09330 240 SER A OG  
3731 N N   . PRO A 241 ? 0.67960 0.59050 0.77610 0.08300  -0.04680 -0.09770 241 PRO A N   
3732 C CA  . PRO A 241 ? 0.69970 0.59030 0.79400 0.07970  -0.04700 -0.08140 241 PRO A CA  
3733 C C   . PRO A 241 ? 0.68300 0.56810 0.75370 0.07750  -0.04310 -0.06230 241 PRO A C   
3734 O O   . PRO A 241 ? 0.72580 0.59610 0.79340 0.07560  -0.04240 -0.04700 241 PRO A O   
3735 C CB  . PRO A 241 ? 0.74040 0.63820 0.83750 0.07240  -0.04280 -0.08860 241 PRO A CB  
3736 C CG  . PRO A 241 ? 0.69260 0.61650 0.78260 0.07060  -0.03850 -0.10300 241 PRO A CG  
3737 C CD  . PRO A 241 ? 0.65790 0.59030 0.74730 0.07680  -0.04010 -0.10800 241 PRO A CD  
3745 N N   . PHE A 242 ? 0.65680 0.55430 0.71200 0.07760  -0.04040 -0.06330 242 PHE A N   
3746 C CA  . PHE A 242 ? 0.64640 0.53940 0.67930 0.07610  -0.03690 -0.04910 242 PHE A CA  
3747 C C   . PHE A 242 ? 0.66930 0.57530 0.69430 0.07730  -0.03760 -0.05530 242 PHE A C   
3748 O O   . PHE A 242 ? 0.66010 0.58120 0.69580 0.07800  -0.03850 -0.06870 242 PHE A O   
3749 C CB  . PHE A 242 ? 0.69140 0.58590 0.71330 0.06940  -0.02850 -0.04260 242 PHE A CB  
3750 C CG  . PHE A 242 ? 0.69390 0.60690 0.71410 0.06490  -0.02380 -0.05210 242 PHE A CG  
3751 C CD1 . PHE A 242 ? 0.67130 0.59220 0.67810 0.06340  -0.02050 -0.05120 242 PHE A CD1 
3752 C CD2 . PHE A 242 ? 0.67090 0.59370 0.70320 0.06170  -0.02320 -0.06170 242 PHE A CD2 
3753 C CE1 . PHE A 242 ? 0.72890 0.66690 0.73540 0.05870  -0.01640 -0.05670 242 PHE A CE1 
3754 C CE2 . PHE A 242 ? 0.68570 0.62800 0.71450 0.05730  -0.01910 -0.06820 242 PHE A CE2 
3755 C CZ  . PHE A 242 ? 0.70680 0.65660 0.72320 0.05580  -0.01560 -0.06430 242 PHE A CZ  
3765 N N   . VAL A 243 ? 0.65740 0.55870 0.66420 0.07730  -0.03700 -0.04590 243 VAL A N   
3766 C CA  . VAL A 243 ? 0.63600 0.54810 0.63500 0.07650  -0.03750 -0.05090 243 VAL A CA  
3767 C C   . VAL A 243 ? 0.61200 0.51920 0.59060 0.07280  -0.03160 -0.04300 243 VAL A C   
3768 O O   . VAL A 243 ? 0.68530 0.58060 0.65320 0.07340  -0.02890 -0.03260 243 VAL A O   
3769 C CB  . VAL A 243 ? 0.67450 0.58640 0.67670 0.08260  -0.04710 -0.05190 243 VAL A CB  
3770 C CG1 . VAL A 243 ? 0.63100 0.54880 0.65750 0.08760  -0.05250 -0.06150 243 VAL A CG1 
3771 C CG2 . VAL A 243 ? 0.70990 0.60620 0.69840 0.08600  -0.05100 -0.03810 243 VAL A CG2 
3781 N N   . MET A 244 ? 0.62440 0.54160 0.59940 0.06890  -0.02910 -0.04810 244 MET A N   
3782 C CA  . MET A 244 ? 0.62590 0.53810 0.58530 0.06580  -0.02390 -0.04350 244 MET A CA  
3783 C C   . MET A 244 ? 0.61610 0.52970 0.56910 0.06620  -0.02950 -0.04770 244 MET A C   
3784 O O   . MET A 244 ? 0.69380 0.62000 0.65750 0.06380  -0.03230 -0.05500 244 MET A O   
3785 C CB  . MET A 244 ? 0.69340 0.61430 0.65720 0.06000  -0.01670 -0.04450 244 MET A CB  
3786 C CG  . MET A 244 ? 0.67480 0.58880 0.62710 0.05770  -0.01120 -0.03990 244 MET A CG  
3787 S SD  . MET A 244 ? 0.66840 0.59350 0.62910 0.05120  -0.00440 -0.03790 244 MET A SD  
3788 C CE  . MET A 244 ? 0.71460 0.62580 0.66450 0.05150  0.00080  -0.03280 244 MET A CE  
3798 N N   . MET A 245 ? 0.66430 0.56710 0.60030 0.06890  -0.03110 -0.04330 245 MET A N   
3799 C CA  . MET A 245 ? 0.68430 0.58790 0.61190 0.06890  -0.03730 -0.04840 245 MET A CA  
3800 C C   . MET A 245 ? 0.69920 0.59630 0.61500 0.06560  -0.03110 -0.04960 245 MET A C   
3801 O O   . MET A 245 ? 0.71700 0.60510 0.62070 0.06740  -0.02440 -0.04400 245 MET A O   
3802 C CB  . MET A 245 ? 0.68210 0.58020 0.59720 0.07480  -0.04520 -0.04380 245 MET A CB  
3803 C CG  . MET A 245 ? 0.71830 0.61960 0.64810 0.07940  -0.05200 -0.04100 245 MET A CG  
3804 S SD  . MET A 245 ? 0.70730 0.62580 0.66160 0.07870  -0.05890 -0.05270 245 MET A SD  
3805 C CE  . MET A 245 ? 0.71590 0.63890 0.65970 0.07830  -0.06900 -0.05720 245 MET A CE  
3815 N N   . SER A 246 ? 0.67940 0.58120 0.60130 0.06070  -0.03300 -0.05700 246 SER A N   
3816 C CA  . SER A 246 ? 0.74750 0.64170 0.66380 0.05750  -0.02790 -0.05950 246 SER A CA  
3817 C C   . SER A 246 ? 0.75430 0.64750 0.66660 0.05540  -0.03600 -0.06900 246 SER A C   
3818 O O   . SER A 246 ? 0.76590 0.66850 0.68460 0.05490  -0.04520 -0.07300 246 SER A O   
3819 C CB  . SER A 246 ? 0.70730 0.60690 0.63970 0.05160  -0.02140 -0.05720 246 SER A CB  
3820 O OG  . SER A 246 ? 0.72880 0.63330 0.66670 0.05280  -0.01630 -0.05050 246 SER A OG  
3826 N N   . ALA A 247 ? 0.76300 0.64530 0.66670 0.05450  -0.03290 -0.07350 247 ALA A N   
3827 C CA  . ALA A 247 ? 0.77600 0.65520 0.67540 0.05200  -0.04080 -0.08490 247 ALA A CA  
3828 C C   . ALA A 247 ? 0.80630 0.67120 0.70140 0.05130  -0.03430 -0.09020 247 ALA A C   
3829 O O   . ALA A 247 ? 0.81870 0.67700 0.70810 0.05520  -0.02440 -0.08450 247 ALA A O   
3830 C CB  . ALA A 247 ? 0.77820 0.65890 0.65750 0.05740  -0.04950 -0.08820 247 ALA A CB  
3836 N N   . PRO A 248 ? 0.81180 0.67180 0.71220 0.04640  -0.04010 -0.10150 248 PRO A N   
3837 C CA  . PRO A 248 ? 0.87760 0.72160 0.77560 0.04680  -0.03500 -0.10920 248 PRO A CA  
3838 C C   . PRO A 248 ? 0.92800 0.76570 0.79890 0.05580  -0.03030 -0.11300 248 PRO A C   
3839 O O   . PRO A 248 ? 0.86650 0.71080 0.71760 0.05960  -0.03600 -0.11480 248 PRO A O   
3840 C CB  . PRO A 248 ? 0.87550 0.71660 0.78210 0.03990  -0.04570 -0.12320 248 PRO A CB  
3841 C CG  . PRO A 248 ? 0.86530 0.72300 0.78910 0.03350  -0.05290 -0.11800 248 PRO A CG  
3842 C CD  . PRO A 248 ? 0.85030 0.71960 0.76300 0.03990  -0.05180 -0.10820 248 PRO A CD  
3850 N N   . PRO A 249 ? 0.94120 0.76810 0.81120 0.05960  -0.01960 -0.11330 249 PRO A N   
3851 C CA  . PRO A 249 ? 0.88720 0.71180 0.73200 0.06850  -0.01280 -0.11600 249 PRO A CA  
3852 C C   . PRO A 249 ? 0.97150 0.79710 0.79260 0.07060  -0.02120 -0.13100 249 PRO A C   
3853 O O   . PRO A 249 ? 1.00860 0.82800 0.83420 0.06660  -0.02900 -0.14650 249 PRO A O   
3854 C CB  . PRO A 249 ? 0.95310 0.76510 0.80800 0.07140  -0.00210 -0.11920 249 PRO A CB  
3855 C CG  . PRO A 249 ? 0.96890 0.77960 0.85320 0.06480  -0.00140 -0.10910 249 PRO A CG  
3856 C CD  . PRO A 249 ? 0.94150 0.75960 0.83490 0.05640  -0.01320 -0.10980 249 PRO A CD  
3864 N N   . ALA A 250 ? 0.92480 0.75920 0.72070 0.07650  -0.02010 -0.12590 250 ALA A N   
3865 C CA  . ALA A 250 ? 1.00100 0.84020 0.76960 0.07910  -0.02830 -0.13780 250 ALA A CA  
3866 C C   . ALA A 250 ? 0.95810 0.80620 0.69980 0.08660  -0.02120 -0.12730 250 ALA A C   
3867 O O   . ALA A 250 ? 0.89160 0.74400 0.63920 0.08760  -0.01580 -0.10880 250 ALA A O   
3868 C CB  . ALA A 250 ? 0.97090 0.81880 0.74360 0.07370  -0.04490 -0.13910 250 ALA A CB  
3874 N N   . GLN A 251 ? 0.92800 0.77960 0.64080 0.09120  -0.02140 -0.13940 251 GLN A N   
3875 C CA  . GLN A 251 ? 0.95630 0.81940 0.64090 0.09770  -0.01470 -0.12850 251 GLN A CA  
3876 C C   . GLN A 251 ? 0.97900 0.85180 0.66250 0.09630  -0.02320 -0.10850 251 GLN A C   
3877 O O   . GLN A 251 ? 0.97630 0.85350 0.66040 0.09320  -0.03860 -0.11130 251 GLN A O   
3878 C CB  . GLN A 251 ? 0.98990 0.85960 0.64060 0.10190  -0.01700 -0.14620 251 GLN A CB  
3879 C CG  . GLN A 251 ? 1.01770 0.87830 0.66740 0.10600  -0.00560 -0.16630 251 GLN A CG  
3880 C CD  . GLN A 251 ? 1.06930 0.93060 0.72250 0.11170  0.01390  -0.15450 251 GLN A CD  
3881 O OE1 . GLN A 251 ? 1.13930 1.01450 0.76940 0.11640  0.02190  -0.14310 251 GLN A OE1 
3882 N NE2 . GLN A 251 ? 1.07410 0.92190 0.75770 0.11090  0.02130  -0.15570 251 GLN A NE2 
3891 N N   . TYR A 252 ? 0.94630 0.82230 0.63120 0.09870  -0.01350 -0.08850 252 TYR A N   
3892 C CA  . TYR A 252 ? 0.88310 0.76460 0.57430 0.09760  -0.02060 -0.06890 252 TYR A CA  
3893 C C   . TYR A 252 ? 0.92150 0.80860 0.60130 0.10130  -0.00930 -0.04950 252 TYR A C   
3894 O O   . TYR A 252 ? 0.90740 0.79210 0.59160 0.10270  0.00560  -0.04770 252 TYR A O   
3895 C CB  . TYR A 252 ? 0.91400 0.78860 0.64050 0.09260  -0.02320 -0.06500 252 TYR A CB  
3896 C CG  . TYR A 252 ? 0.85810 0.73700 0.59530 0.09200  -0.03170 -0.04920 252 TYR A CG  
3897 C CD1 . TYR A 252 ? 0.87170 0.75580 0.61220 0.09080  -0.04760 -0.05250 252 TYR A CD1 
3898 C CD2 . TYR A 252 ? 0.84180 0.71960 0.58880 0.09280  -0.02430 -0.03170 252 TYR A CD2 
3899 C CE1 . TYR A 252 ? 0.87220 0.75970 0.62570 0.09170  -0.05530 -0.03910 252 TYR A CE1 
3900 C CE2 . TYR A 252 ? 0.84450 0.72400 0.60430 0.09280  -0.03240 -0.01900 252 TYR A CE2 
3901 C CZ  . TYR A 252 ? 0.86400 0.74800 0.62720 0.09290  -0.04760 -0.02280 252 TYR A CZ  
3902 O OH  . TYR A 252 ? 0.84400 0.72920 0.62300 0.09430  -0.05560 -0.01110 252 TYR A OH  
3912 N N   . GLU A 253 ? 0.92010 0.81530 0.58770 0.10250  -0.01690 -0.03400 253 GLU A N   
3913 C CA  . GLU A 253 ? 0.97780 0.87950 0.63400 0.10500  -0.00790 -0.01270 253 GLU A CA  
3914 C C   . GLU A 253 ? 0.89050 0.78580 0.57610 0.10220  -0.00850 0.00530  253 GLU A C   
3915 O O   . GLU A 253 ? 0.88670 0.77950 0.58630 0.10090  -0.02180 0.00880  253 GLU A O   
3916 C CB  . GLU A 253 ? 1.03710 0.95200 0.66110 0.10800  -0.01620 -0.00440 253 GLU A CB  
3917 C CG  . GLU A 253 ? 1.10500 1.02970 0.71200 0.11020  -0.00530 0.01790  253 GLU A CG  
3918 C CD  . GLU A 253 ? 1.30230 1.24120 0.87900 0.11260  -0.01570 0.03040  253 GLU A CD  
3919 O OE1 . GLU A 253 ? 1.26840 1.21560 0.82000 0.11450  -0.02400 0.01410  253 GLU A OE1 
3920 O OE2 . GLU A 253 ? 1.30010 1.24200 0.87890 0.11230  -0.01640 0.05690  253 GLU A OE2 
3927 N N   . LEU A 254 ? 0.87890 0.77240 0.57510 0.10150  0.00570  0.01530  254 LEU A N   
3928 C CA  . LEU A 254 ? 0.91720 0.80490 0.64110 0.09840  0.00590  0.03110  254 LEU A CA  
3929 C C   . LEU A 254 ? 0.91890 0.81260 0.63220 0.09920  0.00920  0.05500  254 LEU A C   
3930 O O   . LEU A 254 ? 0.88340 0.78460 0.58440 0.10000  0.02300  0.06200  254 LEU A O   
3931 C CB  . LEU A 254 ? 0.79970 0.68260 0.54590 0.09590  0.01780  0.02690  254 LEU A CB  
3932 C CG  . LEU A 254 ? 0.84880 0.72560 0.60870 0.09420  0.01560  0.00720  254 LEU A CG  
3933 C CD1 . LEU A 254 ? 0.77900 0.65400 0.55630 0.09280  0.02830  0.00610  254 LEU A CD1 
3934 C CD2 . LEU A 254 ? 0.82210 0.69480 0.60200 0.09130  0.00230  0.00490  254 LEU A CD2 
3946 N N   . LYS A 255 ? 0.94320 0.83440 0.66350 0.09900  -0.00330 0.06830  255 LYS A N   
3947 C CA  . LYS A 255 ? 1.02600 0.92140 0.73940 0.09910  -0.00220 0.09410  255 LYS A CA  
3948 C C   . LYS A 255 ? 0.97680 0.86290 0.72280 0.09490  0.00230  0.10800  255 LYS A C   
3949 O O   . LYS A 255 ? 0.90110 0.77710 0.67550 0.09290  -0.00310 0.09970  255 LYS A O   
3950 C CB  . LYS A 255 ? 1.00850 0.90570 0.71300 0.10190  -0.01930 0.10340  255 LYS A CB  
3951 C CG  . LYS A 255 ? 1.13390 1.04550 0.79880 0.10570  -0.02320 0.09810  255 LYS A CG  
3952 C CD  . LYS A 255 ? 1.28440 1.20970 0.91990 0.10630  -0.00830 0.10930  255 LYS A CD  
3953 C CE  . LYS A 255 ? 1.29600 1.23290 0.90860 0.10800  -0.01490 0.13460  255 LYS A CE  
3954 N NZ  . LYS A 255 ? 1.22720 1.17360 0.83060 0.10610  0.00150  0.15670  255 LYS A NZ  
3968 N N   . HIS A 256 ? 0.94070 0.83210 0.68260 0.09300  0.01240  0.12870  256 HIS A N   
3969 C CA  . HIS A 256 ? 0.95650 0.84020 0.72970 0.08780  0.01760  0.14180  256 HIS A CA  
3970 C C   . HIS A 256 ? 0.91350 0.78390 0.71180 0.08690  0.00260  0.15160  256 HIS A C   
3971 O O   . HIS A 256 ? 0.93760 0.80840 0.72570 0.08950  -0.00730 0.16600  256 HIS A O   
3972 C CB  . HIS A 256 ? 0.90890 0.80360 0.67190 0.08540  0.03140  0.16390  256 HIS A CB  
3973 C CG  . HIS A 256 ? 0.92070 0.80780 0.71650 0.07880  0.03430  0.18200  256 HIS A CG  
3974 N ND1 . HIS A 256 ? 0.99660 0.88860 0.79160 0.07540  0.03860  0.21070  256 HIS A ND1 
3975 C CD2 . HIS A 256 ? 0.99930 0.87520 0.83020 0.07440  0.03320  0.17540  256 HIS A CD2 
3976 C CE1 . HIS A 256 ? 0.97520 0.85740 0.80590 0.06880  0.03950  0.22050  256 HIS A CE1 
3977 N NE2 . HIS A 256 ? 0.99580 0.86850 0.84780 0.06830  0.03600  0.19830  256 HIS A NE2 
3985 N N   . GLY A 257 ? 0.96670 0.82600 0.79810 0.08370  0.00060  0.14330  257 GLY A N   
3986 C CA  . GLY A 257 ? 0.84700 0.69280 0.70700 0.08330  -0.01210 0.14960  257 GLY A CA  
3987 C C   . GLY A 257 ? 0.82230 0.66380 0.68880 0.08790  -0.02600 0.13230  257 GLY A C   
3988 O O   . GLY A 257 ? 0.83220 0.66310 0.72460 0.08900  -0.03660 0.13490  257 GLY A O   
3992 N N   . THR A 258 ? 0.80380 0.65360 0.65020 0.09060  -0.02630 0.11430  258 THR A N   
3993 C CA  . THR A 258 ? 0.80250 0.65180 0.65530 0.09430  -0.03890 0.09840  258 THR A CA  
3994 C C   . THR A 258 ? 0.80130 0.65050 0.66950 0.09190  -0.03560 0.07600  258 THR A C   
3995 O O   . THR A 258 ? 0.74030 0.59210 0.61430 0.09400  -0.04390 0.06150  258 THR A O   
3996 C CB  . THR A 258 ? 0.81970 0.67920 0.64090 0.09830  -0.04420 0.09450  258 THR A CB  
3997 O OG1 . THR A 258 ? 0.85890 0.72620 0.65400 0.09680  -0.03140 0.09060  258 THR A OG1 
3998 C CG2 . THR A 258 ? 0.88490 0.74570 0.69600 0.10200  -0.05430 0.11570  258 THR A CG2 
4006 N N   . PHE A 259 ? 0.77310 0.62170 0.64900 0.08730  -0.02380 0.07430  259 PHE A N   
4007 C CA  . PHE A 259 ? 0.73380 0.58450 0.62200 0.08460  -0.02020 0.05590  259 PHE A CA  
4008 C C   . PHE A 259 ? 0.75860 0.60780 0.66140 0.07960  -0.01010 0.06030  259 PHE A C   
4009 O O   . PHE A 259 ? 0.70830 0.55610 0.60870 0.07790  -0.00400 0.07640  259 PHE A O   
4010 C CB  . PHE A 259 ? 0.72120 0.57910 0.58820 0.08540  -0.01640 0.04300  259 PHE A CB  
4011 C CG  . PHE A 259 ? 0.77290 0.63420 0.62170 0.08470  -0.00350 0.04780  259 PHE A CG  
4012 C CD1 . PHE A 259 ? 0.76460 0.62900 0.59080 0.08720  -0.00100 0.06070  259 PHE A CD1 
4013 C CD2 . PHE A 259 ? 0.67970 0.54320 0.53480 0.08200  0.00640  0.04010  259 PHE A CD2 
4014 C CE1 . PHE A 259 ? 0.77150 0.64190 0.58170 0.08740  0.01230  0.06370  259 PHE A CE1 
4015 C CE2 . PHE A 259 ? 0.74670 0.61440 0.58830 0.08270  0.01870  0.04370  259 PHE A CE2 
4016 C CZ  . PHE A 259 ? 0.71240 0.58400 0.53170 0.08550  0.02230  0.05460  259 PHE A CZ  
4026 N N   . THR A 260 ? 0.71470 0.56620 0.63280 0.07670  -0.00850 0.04660  260 THR A N   
4027 C CA  . THR A 260 ? 0.67790 0.53070 0.61110 0.07160  -0.00060 0.04840  260 THR A CA  
4028 C C   . THR A 260 ? 0.67150 0.53150 0.59120 0.07080  0.01100  0.04720  260 THR A C   
4029 O O   . THR A 260 ? 0.70350 0.56570 0.62400 0.06880  0.01990  0.05810  260 THR A O   
4030 C CB  . THR A 260 ? 0.73010 0.58470 0.68550 0.06920  -0.00540 0.03450  260 THR A CB  
4031 O OG1 . THR A 260 ? 0.77080 0.62010 0.73710 0.07230  -0.01650 0.03060  260 THR A OG1 
4032 C CG2 . THR A 260 ? 0.74990 0.60470 0.72490 0.06360  -0.00130 0.03790  260 THR A CG2 
4040 N N   . CYS A 261 ? 0.66220 0.52620 0.57220 0.07230  0.01120  0.03430  261 CYS A N   
4041 C CA  . CYS A 261 ? 0.65170 0.52060 0.55270 0.07250  0.02130  0.03130  261 CYS A CA  
4042 C C   . CYS A 261 ? 0.64280 0.51230 0.53360 0.07430  0.01780  0.01760  261 CYS A C   
4043 O O   . CYS A 261 ? 0.68000 0.54900 0.57470 0.07420  0.00840  0.01030  261 CYS A O   
4044 C CB  . CYS A 261 ? 0.70630 0.58020 0.62660 0.06830  0.02660  0.03130  261 CYS A CB  
4045 S SG  . CYS A 261 ? 0.67580 0.55410 0.61270 0.06480  0.01950  0.01780  261 CYS A SG  
4051 N N   . ALA A 262 ? 0.67160 0.54240 0.55160 0.07610  0.02560  0.01390  262 ALA A N   
4052 C CA  . ALA A 262 ? 0.67390 0.54320 0.54470 0.07730  0.02260  0.00120  262 ALA A CA  
4053 C C   . ALA A 262 ? 0.63580 0.50550 0.50970 0.07770  0.03170  -0.00290 262 ALA A C   
4054 O O   . ALA A 262 ? 0.63660 0.50940 0.51540 0.07850  0.04090  0.00430  262 ALA A O   
4055 C CB  . ALA A 262 ? 0.72890 0.59620 0.57570 0.08140  0.01920  -0.00090 262 ALA A CB  
4061 N N   . SER A 263 ? 0.63780 0.50480 0.51150 0.07720  0.02870  -0.01400 263 SER A N   
4062 C CA  . SER A 263 ? 0.67430 0.53880 0.55260 0.07840  0.03580  -0.01860 263 SER A CA  
4063 C C   . SER A 263 ? 0.73800 0.59580 0.59920 0.08200  0.03550  -0.03030 263 SER A C   
4064 O O   . SER A 263 ? 0.75170 0.60760 0.60510 0.08060  0.02620  -0.03790 263 SER A O   
4065 C CB  . SER A 263 ? 0.69360 0.56000 0.59140 0.07330  0.03250  -0.02030 263 SER A CB  
4066 O OG  . SER A 263 ? 0.70730 0.58180 0.61860 0.06980  0.03140  -0.01230 263 SER A OG  
4072 N N   . GLU A 264 ? 0.70230 0.55790 0.55900 0.08690  0.04540  -0.03280 264 GLU A N   
4073 C CA  . GLU A 264 ? 0.73290 0.58220 0.57440 0.09120  0.04650  -0.04690 264 GLU A CA  
4074 C C   . GLU A 264 ? 0.75480 0.59590 0.61380 0.09150  0.04940  -0.05440 264 GLU A C   
4075 O O   . GLU A 264 ? 0.68640 0.52940 0.56260 0.09240  0.05640  -0.04660 264 GLU A O   
4076 C CB  . GLU A 264 ? 0.81860 0.67310 0.64070 0.09800  0.05680  -0.04580 264 GLU A CB  
4077 C CG  . GLU A 264 ? 0.87580 0.72550 0.68140 0.10360  0.05980  -0.06320 264 GLU A CG  
4078 C CD  . GLU A 264 ? 0.96680 0.82560 0.75490 0.11090  0.07300  -0.06180 264 GLU A CD  
4079 O OE1 . GLU A 264 ? 0.98900 0.84760 0.78740 0.11610  0.08430  -0.06530 264 GLU A OE1 
4080 O OE2 . GLU A 264 ? 1.04200 0.90960 0.80710 0.11160  0.07210  -0.05620 264 GLU A OE2 
4087 N N   . TYR A 265 ? 0.79760 0.62960 0.65390 0.09050  0.04310  -0.06880 265 TYR A N   
4088 C CA  . TYR A 265 ? 0.79960 0.62090 0.67520 0.09000  0.04410  -0.07540 265 TYR A CA  
4089 C C   . TYR A 265 ? 0.79360 0.60470 0.65760 0.09530  0.04580  -0.09440 265 TYR A C   
4090 O O   . TYR A 265 ? 0.85850 0.66850 0.70470 0.09420  0.03810  -0.10600 265 TYR A O   
4091 C CB  . TYR A 265 ? 0.76490 0.58390 0.65700 0.08100  0.03370  -0.07420 265 TYR A CB  
4092 C CG  . TYR A 265 ? 0.80240 0.61050 0.71800 0.07940  0.03470  -0.07590 265 TYR A CG  
4093 C CD1 . TYR A 265 ? 0.78630 0.59720 0.72140 0.07990  0.04070  -0.06250 265 TYR A CD1 
4094 C CD2 . TYR A 265 ? 0.83670 0.63180 0.75650 0.07730  0.02900  -0.09030 265 TYR A CD2 
4095 C CE1 . TYR A 265 ? 0.80360 0.60450 0.76180 0.07870  0.04090  -0.06130 265 TYR A CE1 
4096 C CE2 . TYR A 265 ? 0.87850 0.66150 0.82300 0.07550  0.02950  -0.09020 265 TYR A CE2 
4097 C CZ  . TYR A 265 ? 0.87190 0.65780 0.83540 0.07660  0.03550  -0.07460 265 TYR A CZ  
4098 O OH  . TYR A 265 ? 0.84300 0.61690 0.83250 0.07510  0.03530  -0.07170 265 TYR A OH  
4108 N N   . THR A 266 ? 0.79050 0.59480 0.66610 0.10150  0.05510  -0.09850 266 THR A N   
4109 C CA  . THR A 266 ? 0.84110 0.63380 0.71120 0.10740  0.05740  -0.11930 266 THR A CA  
4110 C C   . THR A 266 ? 0.89460 0.67130 0.79580 0.10590  0.05570  -0.12220 266 THR A C   
4111 O O   . THR A 266 ? 0.92510 0.70240 0.84830 0.10760  0.06170  -0.10910 266 THR A O   
4112 C CB  . THR A 266 ? 0.92560 0.72530 0.78230 0.11840  0.07160  -0.12330 266 THR A CB  
4113 O OG1 . THR A 266 ? 0.95130 0.76650 0.77980 0.11870  0.07290  -0.11710 266 THR A OG1 
4114 C CG2 . THR A 266 ? 0.86680 0.65530 0.71740 0.12550  0.07440  -0.14850 266 THR A CG2 
4122 N N   . GLY A 267 ? 0.95480 0.71770 0.85910 0.10210  0.04680  -0.13830 267 GLY A N   
4123 C CA  . GLY A 267 ? 1.02970 0.77520 0.96540 0.09940  0.04400  -0.14040 267 GLY A CA  
4124 C C   . GLY A 267 ? 1.03220 0.77010 0.97590 0.08810  0.03010  -0.14540 267 GLY A C   
4125 O O   . GLY A 267 ? 1.05750 0.79770 0.98080 0.08550  0.02260  -0.15910 267 GLY A O   
4129 N N   . ASN A 268 ? 1.00000 0.73080 0.97380 0.08100  0.02640  -0.13340 268 ASN A N   
4130 C CA  . ASN A 268 ? 0.98140 0.70700 0.96790 0.06890  0.01430  -0.13540 268 ASN A CA  
4131 C C   . ASN A 268 ? 1.03770 0.77300 1.04500 0.06060  0.01320  -0.11040 268 ASN A C   
4132 O O   . ASN A 268 ? 1.03680 0.78520 1.04180 0.06360  0.01970  -0.09400 268 ASN A O   
4133 C CB  . ASN A 268 ? 1.03700 0.73810 1.04230 0.06850  0.01030  -0.15370 268 ASN A CB  
4134 C CG  . ASN A 268 ? 1.05460 0.74090 1.08940 0.07380  0.01730  -0.14580 268 ASN A CG  
4135 O OD1 . ASN A 268 ? 1.01770 0.71310 1.06430 0.07380  0.02220  -0.12290 268 ASN A OD1 
4136 N ND2 . ASN A 268 ? 1.02610 0.68970 1.07390 0.07850  0.01710  -0.16550 268 ASN A ND2 
4143 N N   . TYR A 269 ? 1.10700 0.83750 1.13480 0.04940  0.00470  -0.10760 269 TYR A N   
4144 C CA  . TYR A 269 ? 1.15370 0.89660 1.19950 0.04050  0.00360  -0.08440 269 TYR A CA  
4145 C C   . TYR A 269 ? 1.12190 0.85690 1.19320 0.04260  0.00910  -0.06840 269 TYR A C   
4146 O O   . TYR A 269 ? 1.14000 0.88810 1.22370 0.03610  0.00910  -0.04720 269 TYR A O   
4147 C CB  . TYR A 269 ? 1.22440 0.96780 1.28460 0.02720  -0.00650 -0.08560 269 TYR A CB  
4148 C CG  . TYR A 269 ? 1.14080 0.90980 1.19660 0.01950  -0.00890 -0.07220 269 TYR A CG  
4149 C CD1 . TYR A 269 ? 1.12960 0.91400 1.15970 0.02280  -0.01010 -0.07810 269 TYR A CD1 
4150 C CD2 . TYR A 269 ? 1.07700 0.85590 1.15530 0.00940  -0.00970 -0.05340 269 TYR A CD2 
4151 C CE1 . TYR A 269 ? 1.13560 0.94270 1.16430 0.01710  -0.01200 -0.06810 269 TYR A CE1 
4152 C CE2 . TYR A 269 ? 1.00020 0.80470 1.07430 0.00330  -0.01080 -0.04350 269 TYR A CE2 
4153 C CZ  . TYR A 269 ? 1.04950 0.86730 1.09980 0.00760  -0.01200 -0.05210 269 TYR A CZ  
4154 O OH  . TYR A 269 ? 1.08290 0.92550 1.13150 0.00280  -0.01290 -0.04450 269 TYR A OH  
4164 N N   . GLN A 270 ? 1.09860 0.81390 1.17810 0.05180  0.01360  -0.07800 270 GLN A N   
4165 C CA  . GLN A 270 ? 1.10780 0.81460 1.21440 0.05550  0.01800  -0.06280 270 GLN A CA  
4166 C C   . GLN A 270 ? 1.06890 0.77940 1.16790 0.06940  0.02840  -0.06200 270 GLN A C   
4167 O O   . GLN A 270 ? 1.05690 0.76640 1.17720 0.07300  0.03200  -0.04570 270 GLN A O   
4168 C CB  . GLN A 270 ? 1.13850 0.81640 1.27330 0.05460  0.01400  -0.07290 270 GLN A CB  
4169 C CG  . GLN A 270 ? 1.21610 0.88440 1.35090 0.04470  0.00410  -0.08990 270 GLN A CG  
4170 C CD  . GLN A 270 ? 1.23830 0.87540 1.40320 0.04410  -0.00020 -0.10220 270 GLN A CD  
4171 O OE1 . GLN A 270 ? 1.20530 0.82940 1.40060 0.04580  0.00160  -0.08800 270 GLN A OE1 
4172 N NE2 . GLN A 270 ? 1.19040 0.81530 1.34820 0.04160  -0.00690 -0.12880 270 GLN A NE2 
4181 N N   . CYS A 271 ? 0.99790 0.71410 1.06820 0.07700  0.03310  -0.07750 271 CYS A N   
4182 C CA  . CYS A 271 ? 0.93540 0.65510 1.00030 0.09020  0.04400  -0.07890 271 CYS A CA  
4183 C C   . CYS A 271 ? 0.95140 0.68420 0.98080 0.09460  0.04820  -0.09040 271 CYS A C   
4184 O O   . CYS A 271 ? 0.99930 0.72590 1.01060 0.09460  0.04480  -0.11030 271 CYS A O   
4185 C CB  . CYS A 271 ? 1.02020 0.71680 1.10450 0.09980  0.04780  -0.09360 271 CYS A CB  
4186 S SG  . CYS A 271 ? 1.10240 0.80440 1.19560 0.11600  0.06160  -0.08920 271 CYS A SG  
4192 N N   . GLY A 272 ? 0.91520 0.66650 0.93520 0.09790  0.05470  -0.07730 272 GLY A N   
4193 C CA  . GLY A 272 ? 0.91650 0.68040 0.90530 0.10140  0.05870  -0.08420 272 GLY A CA  
4194 C C   . GLY A 272 ? 0.84550 0.62780 0.83300 0.10450  0.06620  -0.06750 272 GLY A C   
4195 O O   . GLY A 272 ? 0.81800 0.60430 0.82780 0.10470  0.06810  -0.05210 272 GLY A O   
4199 N N   . HIS A 273 ? 0.82050 0.61460 0.78240 0.10640  0.06970  -0.06990 273 HIS A N   
4200 C CA  . HIS A 273 ? 0.75420 0.56550 0.71400 0.10880  0.07690  -0.05570 273 HIS A CA  
4201 C C   . HIS A 273 ? 0.75950 0.58180 0.69670 0.10330  0.07270  -0.05200 273 HIS A C   
4202 O O   . HIS A 273 ? 0.78580 0.60450 0.70150 0.10290  0.06890  -0.06370 273 HIS A O   
4203 C CB  . HIS A 273 ? 0.83150 0.64570 0.78820 0.12040  0.09020  -0.06200 273 HIS A CB  
4204 C CG  . HIS A 273 ? 0.84900 0.68140 0.81050 0.12220  0.09790  -0.04620 273 HIS A CG  
4205 N ND1 . HIS A 273 ? 0.75150 0.58960 0.74040 0.12350  0.10030  -0.03270 273 HIS A ND1 
4206 C CD2 . HIS A 273 ? 0.79970 0.64620 0.74380 0.12240  0.10320  -0.04100 273 HIS A CD2 
4207 C CE1 . HIS A 273 ? 0.81160 0.66700 0.80010 0.12400  0.10650  -0.02140 273 HIS A CE1 
4208 N NE2 . HIS A 273 ? 0.77990 0.63990 0.74230 0.12310  0.10870  -0.02570 273 HIS A NE2 
4216 N N   . TYR A 274 ? 0.73190 0.56740 0.67520 0.09930  0.07250  -0.03620 274 TYR A N   
4217 C CA  . TYR A 274 ? 0.69250 0.53720 0.62010 0.09440  0.06810  -0.03130 274 TYR A CA  
4218 C C   . TYR A 274 ? 0.71020 0.56550 0.62910 0.09880  0.07730  -0.02480 274 TYR A C   
4219 O O   . TYR A 274 ? 0.67150 0.53250 0.60330 0.10340  0.08630  -0.01910 274 TYR A O   
4220 C CB  . TYR A 274 ? 0.71060 0.56300 0.65160 0.08600  0.06080  -0.02000 274 TYR A CB  
4221 C CG  . TYR A 274 ? 0.67470 0.52250 0.61620 0.07920  0.05040  -0.02500 274 TYR A CG  
4222 C CD1 . TYR A 274 ? 0.66140 0.50980 0.58690 0.07650  0.04370  -0.03080 274 TYR A CD1 
4223 C CD2 . TYR A 274 ? 0.65800 0.50250 0.61780 0.07540  0.04730  -0.02240 274 TYR A CD2 
4224 C CE1 . TYR A 274 ? 0.71680 0.56400 0.64570 0.07030  0.03460  -0.03530 274 TYR A CE1 
4225 C CE2 . TYR A 274 ? 0.66040 0.50340 0.62260 0.06830  0.03880  -0.02570 274 TYR A CE2 
4226 C CZ  . TYR A 274 ? 0.71120 0.55630 0.65840 0.06580  0.03280  -0.03280 274 TYR A CZ  
4227 O OH  . TYR A 274 ? 0.69780 0.54400 0.65010 0.05880  0.02480  -0.03600 274 TYR A OH  
4237 N N   . LYS A 275 ? 0.64170 0.50050 0.54070 0.09720  0.07470  -0.02450 275 LYS A N   
4238 C CA  . LYS A 275 ? 0.67760 0.54710 0.56920 0.09900  0.08190  -0.01480 275 LYS A CA  
4239 C C   . LYS A 275 ? 0.62020 0.49310 0.50800 0.09230  0.07340  -0.00670 275 LYS A C   
4240 O O   . LYS A 275 ? 0.61770 0.48530 0.49950 0.08880  0.06310  -0.01220 275 LYS A O   
4241 C CB  . LYS A 275 ? 0.65890 0.52930 0.52680 0.10590  0.08970  -0.02250 275 LYS A CB  
4242 C CG  . LYS A 275 ? 0.67110 0.54490 0.54600 0.11420  0.10330  -0.02650 275 LYS A CG  
4243 C CD  . LYS A 275 ? 0.73210 0.61190 0.58110 0.12110  0.11240  -0.03380 275 LYS A CD  
4244 C CE  . LYS A 275 ? 0.78040 0.65480 0.63060 0.13020  0.12030  -0.05140 275 LYS A CE  
4245 N NZ  . LYS A 275 ? 0.88700 0.77140 0.71080 0.13750  0.13110  -0.05980 275 LYS A NZ  
4259 N N   . HIS A 276 ? 0.65770 0.53970 0.55170 0.09070  0.07750  0.00620  276 HIS A N   
4260 C CA  . HIS A 276 ? 0.66460 0.54850 0.55980 0.08500  0.06990  0.01410  276 HIS A CA  
4261 C C   . HIS A 276 ? 0.65980 0.54660 0.53800 0.08670  0.07370  0.02160  276 HIS A C   
4262 O O   . HIS A 276 ? 0.71300 0.60690 0.58780 0.09030  0.08520  0.02690  276 HIS A O   
4263 C CB  . HIS A 276 ? 0.60930 0.50060 0.52840 0.08010  0.06970  0.02320  276 HIS A CB  
4264 C CG  . HIS A 276 ? 0.63760 0.52930 0.56160 0.07440  0.06150  0.02850  276 HIS A CG  
4265 N ND1 . HIS A 276 ? 0.68690 0.57680 0.61740 0.07030  0.05120  0.02280  276 HIS A ND1 
4266 C CD2 . HIS A 276 ? 0.65390 0.54750 0.57950 0.07230  0.06230  0.03870  276 HIS A CD2 
4267 C CE1 . HIS A 276 ? 0.65000 0.53990 0.58590 0.06690  0.04580  0.02720  276 HIS A CE1 
4268 N NE2 . HIS A 276 ? 0.66390 0.55470 0.59790 0.06770  0.05180  0.03760  276 HIS A NE2 
4276 N N   . ILE A 277 ? 0.65580 0.53850 0.52460 0.08440  0.06420  0.02300  277 ILE A N   
4277 C CA  . ILE A 277 ? 0.71470 0.59990 0.56780 0.08550  0.06540  0.03310  277 ILE A CA  
4278 C C   . ILE A 277 ? 0.73540 0.61800 0.60240 0.08010  0.05670  0.04280  277 ILE A C   
4279 O O   . ILE A 277 ? 0.68020 0.55710 0.55190 0.07830  0.04550  0.03620  277 ILE A O   
4280 C CB  . ILE A 277 ? 0.71850 0.60080 0.54420 0.08950  0.06080  0.02480  277 ILE A CB  
4281 C CG1 . ILE A 277 ? 0.81940 0.70460 0.63030 0.09540  0.07080  0.01420  277 ILE A CG1 
4282 C CG2 . ILE A 277 ? 0.77300 0.65830 0.58330 0.08970  0.05840  0.03820  277 ILE A CG2 
4283 C CD1 . ILE A 277 ? 0.87280 0.74960 0.68160 0.09660  0.06470  -0.00430 277 ILE A CD1 
4295 N N   . THR A 278 ? 0.72200 0.60890 0.59740 0.07760  0.06190  0.05790  278 THR A N   
4296 C CA  . THR A 278 ? 0.72520 0.60780 0.61780 0.07240  0.05410  0.06700  278 THR A CA  
4297 C C   . THR A 278 ? 0.69190 0.57420 0.57360 0.07260  0.05470  0.08330  278 THR A C   
4298 O O   . THR A 278 ? 0.73710 0.62790 0.60600 0.07440  0.06570  0.09240  278 THR A O   
4299 C CB  . THR A 278 ? 0.69820 0.58540 0.61790 0.06710  0.05780  0.07130  278 THR A CB  
4300 O OG1 . THR A 278 ? 0.72690 0.60830 0.66440 0.06200  0.04950  0.07790  278 THR A OG1 
4301 C CG2 . THR A 278 ? 0.65070 0.54860 0.57140 0.06740  0.07190  0.08230  278 THR A CG2 
4309 N N   . SER A 279 ? 0.70390 0.57750 0.59190 0.07110  0.04310  0.08770  279 SER A N   
4310 C CA  . SER A 279 ? 0.80420 0.67590 0.68280 0.07150  0.04070  0.10510  279 SER A CA  
4311 C C   . SER A 279 ? 0.81070 0.67760 0.71680 0.06520  0.03960  0.12010  279 SER A C   
4312 O O   . SER A 279 ? 0.79340 0.65000 0.72000 0.06310  0.02880  0.11680  279 SER A O   
4313 C CB  . SER A 279 ? 0.77260 0.63740 0.64060 0.07540  0.02690  0.10010  279 SER A CB  
4314 O OG  . SER A 279 ? 0.82710 0.69060 0.68550 0.07630  0.02330  0.11890  279 SER A OG  
4320 N N   . LYS A 280 ? 0.85920 0.73430 0.76730 0.06200  0.05120  0.13600  280 LYS A N   
4321 C CA  . LYS A 280 ? 0.89810 0.76950 0.83370 0.05460  0.05120  0.15260  280 LYS A CA  
4322 C C   . LYS A 280 ? 0.91440 0.78830 0.83760 0.05410  0.05440  0.17740  280 LYS A C   
4323 O O   . LYS A 280 ? 0.93870 0.80850 0.84200 0.05880  0.04690  0.18050  280 LYS A O   
4324 C CB  . LYS A 280 ? 0.89790 0.77950 0.85220 0.04970  0.06170  0.15140  280 LYS A CB  
4325 C CG  . LYS A 280 ? 0.83990 0.72320 0.80070 0.05110  0.05990  0.12930  280 LYS A CG  
4326 C CD  . LYS A 280 ? 0.93870 0.80990 0.91820 0.04870  0.04560  0.11750  280 LYS A CD  
4327 C CE  . LYS A 280 ? 1.12430 0.99110 1.13650 0.04030  0.04210  0.12560  280 LYS A CE  
4328 N NZ  . LYS A 280 ? 1.16450 1.02310 1.19510 0.03860  0.02970  0.10890  280 LYS A NZ  
4342 N N   . GLU A 281 ? 0.93410 0.81630 0.86920 0.04800  0.06490  0.19640  281 GLU A N   
4343 C CA  . GLU A 281 ? 0.89730 0.78660 0.81710 0.04720  0.07050  0.22230  281 GLU A CA  
4344 C C   . GLU A 281 ? 0.94060 0.84360 0.81740 0.05540  0.07720  0.21820  281 GLU A C   
4345 O O   . GLU A 281 ? 0.97780 0.88550 0.83280 0.05710  0.07670  0.23540  281 GLU A O   
4346 C CB  . GLU A 281 ? 0.88270 0.78390 0.82250 0.03900  0.08390  0.24110  281 GLU A CB  
4347 C CG  . GLU A 281 ? 0.92580 0.84510 0.86440 0.04030  0.09890  0.22940  281 GLU A CG  
4348 C CD  . GLU A 281 ? 0.98450 0.89810 0.95500 0.03630  0.09440  0.21300  281 GLU A CD  
4349 O OE1 . GLU A 281 ? 0.98900 0.88580 0.96970 0.03640  0.07980  0.19930  281 GLU A OE1 
4350 O OE2 . GLU A 281 ? 1.01720 0.94550 1.00240 0.03330  0.10560  0.21380  281 GLU A OE2 
4357 N N   . THR A 282 ? 0.91790 0.82770 0.78260 0.06050  0.08310  0.19560  282 THR A N   
4358 C CA  . THR A 282 ? 0.91360 0.83290 0.74010 0.06880  0.08690  0.18440  282 THR A CA  
4359 C C   . THR A 282 ? 0.83070 0.74430 0.65890 0.07290  0.08360  0.15580  282 THR A C   
4360 O O   . THR A 282 ? 0.84940 0.75320 0.70490 0.06940  0.07770  0.14740  282 THR A O   
4361 C CB  . THR A 282 ? 0.89950 0.84130 0.70730 0.07020  0.10580  0.19470  282 THR A CB  
4362 O OG1 . THR A 282 ? 0.94240 0.89300 0.71090 0.07840  0.10800  0.18260  282 THR A OG1 
4363 C CG2 . THR A 282 ? 0.85910 0.80980 0.68750 0.06910  0.11910  0.18670  282 THR A CG2 
4371 N N   . LEU A 283 ? 0.84480 0.76510 0.64410 0.07980  0.08720  0.14090  283 LEU A N   
4372 C CA  . LEU A 283 ? 0.78950 0.70390 0.59060 0.08330  0.08430  0.11560  283 LEU A CA  
4373 C C   . LEU A 283 ? 0.78390 0.70800 0.59570 0.08440  0.09930  0.10970  283 LEU A C   
4374 O O   . LEU A 283 ? 0.82030 0.75900 0.61610 0.08820  0.11320  0.11260  283 LEU A O   
4375 C CB  . LEU A 283 ? 0.78290 0.69770 0.55190 0.08970  0.07930  0.10090  283 LEU A CB  
4376 C CG  . LEU A 283 ? 0.88390 0.79120 0.64240 0.08980  0.06300  0.10510  283 LEU A CG  
4377 C CD1 . LEU A 283 ? 0.90790 0.81800 0.63610 0.09540  0.05790  0.08800  283 LEU A CD1 
4378 C CD2 . LEU A 283 ? 0.83420 0.72670 0.62170 0.08600  0.04990  0.10130  283 LEU A CD2 
4390 N N   . TYR A 284 ? 0.75560 0.67320 0.59440 0.08160  0.09640  0.10150  284 TYR A N   
4391 C CA  . TYR A 284 ? 0.78010 0.70620 0.63340 0.08310  0.10800  0.09570  284 TYR A CA  
4392 C C   . TYR A 284 ? 0.74420 0.66290 0.59580 0.08740  0.10370  0.07410  284 TYR A C   
4393 O O   . TYR A 284 ? 0.75400 0.66110 0.61100 0.08510  0.09070  0.06630  284 TYR A O   
4394 C CB  . TYR A 284 ? 0.72830 0.65580 0.61620 0.07570  0.10760  0.10570  284 TYR A CB  
4395 C CG  . TYR A 284 ? 0.69550 0.63130 0.59170 0.07030  0.11380  0.12800  284 TYR A CG  
4396 C CD1 . TYR A 284 ? 0.77950 0.73350 0.67270 0.07210  0.13050  0.13750  284 TYR A CD1 
4397 C CD2 . TYR A 284 ? 0.76550 0.69140 0.67480 0.06330  0.10320  0.13990  284 TYR A CD2 
4398 C CE1 . TYR A 284 ? 0.73530 0.69860 0.63790 0.06600  0.13680  0.16010  284 TYR A CE1 
4399 C CE2 . TYR A 284 ? 0.83370 0.76570 0.75380 0.05730  0.10840  0.16210  284 TYR A CE2 
4400 C CZ  . TYR A 284 ? 0.75720 0.70850 0.67370 0.05810  0.12530  0.17310  284 TYR A CZ  
4401 O OH  . TYR A 284 ? 0.82460 0.78370 0.75350 0.05090  0.13110  0.19730  284 TYR A OH  
4411 N N   . CYS A 285 ? 0.73810 0.66380 0.58400 0.09370  0.11500  0.06470  285 CYS A N   
4412 C CA  . CYS A 285 ? 0.75400 0.67200 0.60320 0.09760  0.11220  0.04620  285 CYS A CA  
4413 C C   . CYS A 285 ? 0.72480 0.64870 0.60280 0.09750  0.11890  0.04780  285 CYS A C   
4414 O O   . CYS A 285 ? 0.70780 0.64460 0.59050 0.10140  0.13260  0.05220  285 CYS A O   
4415 C CB  . CYS A 285 ? 0.76490 0.68390 0.58830 0.10580  0.11830  0.03160  285 CYS A CB  
4416 S SG  . CYS A 285 ? 0.84740 0.75330 0.67830 0.10980  0.11370  0.00930  285 CYS A SG  
4422 N N   . ILE A 286 ? 0.67670 0.59340 0.57380 0.09320  0.10910  0.04490  286 ILE A N   
4423 C CA  . ILE A 286 ? 0.72130 0.64440 0.64580 0.09250  0.11230  0.04730  286 ILE A CA  
4424 C C   . ILE A 286 ? 0.63550 0.55090 0.56200 0.09740  0.11070  0.03330  286 ILE A C   
4425 O O   . ILE A 286 ? 0.67930 0.58400 0.60290 0.09460  0.09970  0.02590  286 ILE A O   
4426 C CB  . ILE A 286 ? 0.69960 0.62320 0.64440 0.08360  0.10240  0.05490  286 ILE A CB  
4427 C CG1 . ILE A 286 ? 0.71790 0.64470 0.66250 0.07820  0.10230  0.06800  286 ILE A CG1 
4428 C CG2 . ILE A 286 ? 0.64950 0.58340 0.62140 0.08280  0.10520  0.05850  286 ILE A CG2 
4429 C CD1 . ILE A 286 ? 0.69840 0.62550 0.66540 0.06950  0.09290  0.07340  286 ILE A CD1 
4441 N N   . ASP A 287 ? 0.65380 0.57490 0.58760 0.10470  0.12180  0.03010  287 ASP A N   
4442 C CA  . ASP A 287 ? 0.67700 0.58980 0.61860 0.11010  0.12120  0.01860  287 ASP A CA  
4443 C C   . ASP A 287 ? 0.61300 0.53550 0.58540 0.11060  0.12420  0.02710  287 ASP A C   
4444 O O   . ASP A 287 ? 0.62160 0.55310 0.60510 0.11810  0.13580  0.02750  287 ASP A O   
4445 C CB  . ASP A 287 ? 0.72800 0.63770 0.65290 0.12000  0.13100  0.00490  287 ASP A CB  
4446 C CG  . ASP A 287 ? 0.73500 0.63120 0.66880 0.12490  0.12840  -0.00880 287 ASP A CG  
4447 O OD1 . ASP A 287 ? 0.74040 0.62960 0.68970 0.11980  0.11840  -0.00580 287 ASP A OD1 
4448 O OD2 . ASP A 287 ? 0.80520 0.69810 0.73090 0.13380  0.13640  -0.02240 287 ASP A OD2 
4453 N N   . GLY A 288 ? 0.63270 0.55020 0.64970 0.08150  0.03430  0.01440  288 GLY A N   
4454 C CA  . GLY A 288 ? 0.62950 0.56990 0.65840 0.09420  0.03250  0.00930  288 GLY A CA  
4455 C C   . GLY A 288 ? 0.62490 0.58090 0.66010 0.08950  0.03760  -0.00960 288 GLY A C   
4456 O O   . GLY A 288 ? 0.61900 0.57930 0.65270 0.08220  0.03990  -0.01330 288 GLY A O   
4460 N N   . ALA A 289 ? 0.62900 0.59350 0.67460 0.09330  0.04010  -0.02280 289 ALA A N   
4461 C CA  . ALA A 289 ? 0.65740 0.63720 0.71240 0.08660  0.04730  -0.04290 289 ALA A CA  
4462 C C   . ALA A 289 ? 0.63630 0.59880 0.68270 0.06940  0.05690  -0.04730 289 ALA A C   
4463 O O   . ALA A 289 ? 0.64060 0.61230 0.69400 0.06060  0.06590  -0.06130 289 ALA A O   
4464 C CB  . ALA A 289 ? 0.62820 0.62990 0.69950 0.09910  0.04560  -0.05750 289 ALA A CB  
4470 N N   . LEU A 290 ? 0.64080 0.58140 0.67330 0.06480  0.05590  -0.03630 290 LEU A N   
4471 C CA  . LEU A 290 ? 0.70070 0.63080 0.72220 0.05150  0.06410  -0.04010 290 LEU A CA  
4472 C C   . LEU A 290 ? 0.69470 0.61220 0.70050 0.04140  0.06760  -0.02920 290 LEU A C   
4473 O O   . LEU A 290 ? 0.70870 0.61860 0.70900 0.04460  0.06070  -0.01660 290 LEU A O   
4474 C CB  . LEU A 290 ? 0.65840 0.57700 0.67580 0.05320  0.06070  -0.03840 290 LEU A CB  
4475 C CG  . LEU A 290 ? 0.66460 0.59070 0.70040 0.06360  0.05760  -0.04880 290 LEU A CG  
4476 C CD1 . LEU A 290 ? 0.66820 0.58030 0.70550 0.06430  0.05430  -0.04770 290 LEU A CD1 
4477 C CD2 . LEU A 290 ? 0.66300 0.60690 0.70780 0.06030  0.06530  -0.06900 290 LEU A CD2 
4489 N N   . LEU A 291 ? 0.66510 0.58110 0.66420 0.02990  0.07870  -0.03330 291 LEU A N   
4490 C CA  . LEU A 291 ? 0.69330 0.59550 0.67820 0.02140  0.08360  -0.02120 291 LEU A CA  
4491 C C   . LEU A 291 ? 0.69750 0.59400 0.66310 0.01290  0.09220  -0.01830 291 LEU A C   
4492 O O   . LEU A 291 ? 0.70120 0.60880 0.67070 0.00740  0.10210  -0.02970 291 LEU A O   
4493 C CB  . LEU A 291 ? 0.71800 0.62570 0.71890 0.01620  0.09160  -0.02660 291 LEU A CB  
4494 C CG  . LEU A 291 ? 0.68730 0.57760 0.67930 0.00700  0.09950  -0.01420 291 LEU A CG  
4495 C CD1 . LEU A 291 ? 0.68740 0.56420 0.66760 0.01280  0.08800  0.00100  291 LEU A CD1 
4496 C CD2 . LEU A 291 ? 0.70700 0.60400 0.72460 0.00090  0.10920  -0.02480 291 LEU A CD2 
4508 N N   . THR A 292 ? 0.73640 0.61990 0.68110 0.01280  0.08810  -0.00420 292 THR A N   
4509 C CA  . THR A 292 ? 0.74030 0.62210 0.66200 0.00700  0.09560  0.00130  292 THR A CA  
4510 C C   . THR A 292 ? 0.77970 0.64520 0.68440 0.00620  0.09540  0.02060  292 THR A C   
4511 O O   . THR A 292 ? 0.74530 0.60170 0.65540 0.01090  0.08640  0.02700  292 THR A O   
4512 C CB  . THR A 292 ? 0.76940 0.65910 0.68250 0.01140  0.08850  -0.00550 292 THR A CB  
4513 O OG1 . THR A 292 ? 0.78000 0.66070 0.69020 0.01800  0.07560  0.00180  292 THR A OG1 
4514 C CG2 . THR A 292 ? 0.71500 0.61790 0.64930 0.01420  0.08750  -0.02440 292 THR A CG2 
4522 N N   . LYS A 293 ? 0.76600 0.62920 0.64960 0.00120  0.10560  0.03040  293 LYS A N   
4523 C CA  . LYS A 293 ? 0.80100 0.64740 0.66750 0.00200  0.10680  0.05100  293 LYS A CA  
4524 C C   . LYS A 293 ? 0.90770 0.76040 0.74200 0.00590  0.10570  0.06000  293 LYS A C   
4525 O O   . LYS A 293 ? 0.87590 0.74750 0.70170 0.00480  0.10900  0.04960  293 LYS A O   
4526 C CB  . LYS A 293 ? 0.86190 0.69640 0.73680 -0.00710 0.12360  0.05960  293 LYS A CB  
4527 C CG  . LYS A 293 ? 0.86460 0.70780 0.72820 -0.01590 0.14170  0.06120  293 LYS A CG  
4528 C CD  . LYS A 293 ? 0.88540 0.71190 0.75860 -0.02580 0.16030  0.07380  293 LYS A CD  
4529 C CE  . LYS A 293 ? 1.01810 0.84790 0.86630 -0.03190 0.17840  0.08870  293 LYS A CE  
4530 N NZ  . LYS A 293 ? 1.09040 0.89650 0.94620 -0.04060 0.19750  0.10820  293 LYS A NZ  
4544 N N   . SER A 294 ? 0.88170 0.72160 0.69900 0.01170  0.10050  0.07760  294 SER A N   
4545 C CA  . SER A 294 ? 0.98030 0.82880 0.76470 0.01840  0.09840  0.08800  294 SER A CA  
4546 C C   . SER A 294 ? 0.99190 0.82070 0.76410 0.02520  0.09440  0.11000  294 SER A C   
4547 O O   . SER A 294 ? 0.93100 0.74320 0.72260 0.02580  0.08870  0.11150  294 SER A O   
4548 C CB  . SER A 294 ? 0.97220 0.84090 0.75400 0.02500  0.08400  0.07090  294 SER A CB  
4549 O OG  . SER A 294 ? 0.97860 0.83850 0.77330 0.03030  0.06930  0.06880  294 SER A OG  
4555 N N   . SER A 295 ? 0.98980 0.82320 0.72960 0.03190  0.09730  0.12670  295 SER A N   
4556 C CA  . SER A 295 ? 1.00590 0.82120 0.73190 0.04150  0.09230  0.14880  295 SER A CA  
4557 C C   . SER A 295 ? 0.97440 0.80020 0.69520 0.05340  0.07120  0.14070  295 SER A C   
4558 O O   . SER A 295 ? 0.95430 0.76410 0.67940 0.06000  0.06270  0.14980  295 SER A O   
4559 C CB  . SER A 295 ? 1.02050 0.83680 0.71200 0.04620  0.10450  0.17380  295 SER A CB  
4560 O OG  . SER A 295 ? 1.08310 0.93330 0.75140 0.04870  0.10520  0.16420  295 SER A OG  
4566 N N   . GLU A 296 ? 0.98340 0.83690 0.69870 0.05580  0.06330  0.12150  296 GLU A N   
4567 C CA  . GLU A 296 ? 0.98630 0.85330 0.70180 0.06510  0.04500  0.10950  296 GLU A CA  
4568 C C   . GLU A 296 ? 0.99920 0.87640 0.74240 0.05820  0.03980  0.08340  296 GLU A C   
4569 O O   . GLU A 296 ? 0.97460 0.86000 0.72610 0.05050  0.04820  0.07210  296 GLU A O   
4570 C CB  . GLU A 296 ? 1.05020 0.94480 0.73270 0.07730  0.03990  0.11070  296 GLU A CB  
4571 C CG  . GLU A 296 ? 1.11080 0.99540 0.76300 0.08870  0.04250  0.14020  296 GLU A CG  
4572 C CD  . GLU A 296 ? 1.28410 1.19860 0.89850 0.09820  0.04670  0.14700  296 GLU A CD  
4573 O OE1 . GLU A 296 ? 1.39230 1.30910 0.97800 0.11350  0.04260  0.16750  296 GLU A OE1 
4574 O OE2 . GLU A 296 ? 1.38240 1.32030 0.99550 0.09160  0.05390  0.13180  296 GLU A OE2 
4581 N N   . TYR A 297 ? 0.95840 0.83510 0.71710 0.06140  0.02660  0.07470  297 TYR A N   
4582 C CA  . TYR A 297 ? 0.98040 0.86250 0.76720 0.05570  0.02250  0.05450  297 TYR A CA  
4583 C C   . TYR A 297 ? 0.96990 0.86750 0.76150 0.06150  0.00920  0.04110  297 TYR A C   
4584 O O   . TYR A 297 ? 0.98070 0.87600 0.76540 0.06850  0.00050  0.04820  297 TYR A O   
4585 C CB  . TYR A 297 ? 0.93630 0.79850 0.74770 0.05000  0.02400  0.05820  297 TYR A CB  
4586 C CG  . TYR A 297 ? 0.97200 0.83810 0.80950 0.04440  0.02470  0.04270  297 TYR A CG  
4587 C CD1 . TYR A 297 ? 0.93850 0.80800 0.79380 0.04540  0.01600  0.03360  297 TYR A CD1 
4588 C CD2 . TYR A 297 ? 0.94380 0.80990 0.78900 0.03860  0.03460  0.03780  297 TYR A CD2 
4589 C CE1 . TYR A 297 ? 0.90470 0.77450 0.78410 0.04170  0.01770  0.02340  297 TYR A CE1 
4590 C CE2 . TYR A 297 ? 0.88920 0.75780 0.75820 0.03610  0.03450  0.02530  297 TYR A CE2 
4591 C CZ  . TYR A 297 ? 0.98700 0.85590 0.87270 0.03810  0.02620  0.01970  297 TYR A CZ  
4592 O OH  . TYR A 297 ? 1.00610 0.87430 0.91590 0.03680  0.02720  0.01100  297 TYR A OH  
4602 N N   . LYS A 298 ? 0.95250 0.86610 0.75970 0.05840  0.00790  0.01990  298 LYS A N   
4603 C CA  . LYS A 298 ? 0.96150 0.89000 0.78340 0.06090  -0.00240 0.00260  298 LYS A CA  
4604 C C   . LYS A 298 ? 0.94450 0.86970 0.80080 0.05280  0.00040  -0.01310 298 LYS A C   
4605 O O   . LYS A 298 ? 0.96780 0.89760 0.82990 0.04910  0.00720  -0.02210 298 LYS A O   
4606 C CB  . LYS A 298 ? 1.03010 0.99010 0.83380 0.06890  -0.00750 -0.01090 298 LYS A CB  
4607 C CG  . LYS A 298 ? 1.07560 1.05430 0.89470 0.07260  -0.01900 -0.03030 298 LYS A CG  
4608 C CD  . LYS A 298 ? 1.21090 1.22870 1.01760 0.08070  -0.02390 -0.05080 298 LYS A CD  
4609 C CE  . LYS A 298 ? 1.22510 1.26470 1.05660 0.08230  -0.03410 -0.07680 298 LYS A CE  
4610 N NZ  . LYS A 298 ? 1.26420 1.31330 1.13430 0.07310  -0.03050 -0.10550 298 LYS A NZ  
4624 N N   . GLY A 299 ? 0.92730 0.84480 0.80670 0.05040  -0.00410 -0.01530 299 GLY A N   
4625 C CA  . GLY A 299 ? 0.84720 0.75780 0.75990 0.04390  -0.00050 -0.02500 299 GLY A CA  
4626 C C   . GLY A 299 ? 0.83420 0.73970 0.76890 0.04180  -0.00460 -0.02510 299 GLY A C   
4627 O O   . GLY A 299 ? 0.77240 0.68320 0.69790 0.04530  -0.01150 -0.02150 299 GLY A O   
4631 N N   . PRO A 300 ? 0.79640 0.69210 0.76160 0.03660  0.00020  -0.02850 300 PRO A N   
4632 C CA  . PRO A 300 ? 0.75710 0.64770 0.74560 0.03320  -0.00050 -0.02620 300 PRO A CA  
4633 C C   . PRO A 300 ? 0.75980 0.63930 0.73990 0.03470  -0.00050 -0.00420 300 PRO A C   
4634 O O   . PRO A 300 ? 0.78060 0.64860 0.77300 0.03370  0.00490  0.00700  300 PRO A O   
4635 C CB  . PRO A 300 ? 0.72650 0.60820 0.74930 0.02830  0.00670  -0.03430 300 PRO A CB  
4636 C CG  . PRO A 300 ? 0.82300 0.69840 0.83720 0.03060  0.01100  -0.03110 300 PRO A CG  
4637 C CD  . PRO A 300 ? 0.77540 0.66440 0.75610 0.03420  0.00740  -0.03400 300 PRO A CD  
4645 N N   . ILE A 301 ? 0.71150 0.59700 0.67080 0.03870  -0.00720 0.00130  301 ILE A N   
4646 C CA  . ILE A 301 ? 0.75310 0.63270 0.70620 0.04080  -0.00830 0.01770  301 ILE A CA  
4647 C C   . ILE A 301 ? 0.73520 0.61900 0.70880 0.03770  -0.00880 0.01870  301 ILE A C   
4648 O O   . ILE A 301 ? 0.73010 0.62400 0.71470 0.03520  -0.01170 0.00630  301 ILE A O   
4649 C CB  . ILE A 301 ? 0.71820 0.60080 0.64540 0.04690  -0.01500 0.02260  301 ILE A CB  
4650 C CG1 . ILE A 301 ? 0.78150 0.66110 0.68830 0.04900  -0.01200 0.02310  301 ILE A CG1 
4651 C CG2 . ILE A 301 ? 0.77330 0.65080 0.69950 0.04890  -0.01570 0.03580  301 ILE A CG2 
4652 C CD1 . ILE A 301 ? 0.83450 0.70400 0.74610 0.04560  -0.00310 0.02760  301 ILE A CD1 
4664 N N   . THR A 302 ? 0.69050 0.57010 0.66990 0.03790  -0.00530 0.03240  302 THR A N   
4665 C CA  . THR A 302 ? 0.71650 0.60230 0.71330 0.03500  -0.00350 0.03700  302 THR A CA  
4666 C C   . THR A 302 ? 0.66350 0.55860 0.65180 0.03920  -0.00760 0.04630  302 THR A C   
4667 O O   . THR A 302 ? 0.66580 0.57200 0.66490 0.03710  -0.00760 0.04760  302 THR A O   
4668 C CB  . THR A 302 ? 0.73760 0.61440 0.75470 0.03240  0.00630  0.04560  302 THR A CB  
4669 O OG1 . THR A 302 ? 0.84750 0.73020 0.88300 0.02810  0.01050  0.05090  302 THR A OG1 
4670 C CG2 . THR A 302 ? 0.67380 0.54770 0.68180 0.03850  0.00860  0.05910  302 THR A CG2 
4678 N N   . ASP A 303 ? 0.63230 0.52490 0.60460 0.04440  -0.01020 0.05090  303 ASP A N   
4679 C CA  . ASP A 303 ? 0.67680 0.57990 0.64560 0.04870  -0.01440 0.05540  303 ASP A CA  
4680 C C   . ASP A 303 ? 0.67100 0.56670 0.62390 0.05290  -0.01850 0.05420  303 ASP A C   
4681 O O   . ASP A 303 ? 0.64750 0.53200 0.59350 0.05250  -0.01420 0.05540  303 ASP A O   
4682 C CB  . ASP A 303 ? 0.62590 0.53690 0.60290 0.05100  -0.00910 0.06510  303 ASP A CB  
4683 C CG  . ASP A 303 ? 0.68450 0.60130 0.67660 0.04770  -0.00300 0.07190  303 ASP A CG  
4684 O OD1 . ASP A 303 ? 0.74850 0.67880 0.74720 0.04570  -0.00450 0.07120  303 ASP A OD1 
4685 O OD2 . ASP A 303 ? 0.74630 0.65400 0.74530 0.04740  0.00410  0.07860  303 ASP A OD2 
4690 N N   . VAL A 304 ? 0.63660 0.53820 0.58600 0.05680  -0.02590 0.05200  304 VAL A N   
4691 C CA  . VAL A 304 ? 0.66730 0.55880 0.60540 0.06120  -0.02880 0.05340  304 VAL A CA  
4692 C C   . VAL A 304 ? 0.67450 0.57640 0.62240 0.06540  -0.03320 0.05200  304 VAL A C   
4693 O O   . VAL A 304 ? 0.66780 0.58520 0.62330 0.06700  -0.03890 0.04760  304 VAL A O   
4694 C CB  . VAL A 304 ? 0.65620 0.54150 0.57870 0.06470  -0.03470 0.05120  304 VAL A CB  
4695 C CG1 . VAL A 304 ? 0.66510 0.53540 0.57530 0.06940  -0.03470 0.05800  304 VAL A CG1 
4696 C CG2 . VAL A 304 ? 0.67230 0.55560 0.58880 0.06090  -0.03120 0.04740  304 VAL A CG2 
4706 N N   . PHE A 305 ? 0.65370 0.54960 0.60480 0.06680  -0.03010 0.05320  305 PHE A N   
4707 C CA  . PHE A 305 ? 0.64230 0.55000 0.60820 0.07080  -0.03360 0.04780  305 PHE A CA  
4708 C C   . PHE A 305 ? 0.65830 0.54830 0.62200 0.07480  -0.03660 0.04860  305 PHE A C   
4709 O O   . PHE A 305 ? 0.67480 0.54390 0.62850 0.07310  -0.03080 0.05530  305 PHE A O   
4710 C CB  . PHE A 305 ? 0.66610 0.58500 0.64460 0.06990  -0.02730 0.04500  305 PHE A CB  
4711 C CG  . PHE A 305 ? 0.67360 0.61250 0.65530 0.06940  -0.02490 0.04710  305 PHE A CG  
4712 C CD1 . PHE A 305 ? 0.70960 0.63870 0.68310 0.06570  -0.01940 0.05420  305 PHE A CD1 
4713 C CD2 . PHE A 305 ? 0.67970 0.64800 0.67360 0.07340  -0.02770 0.04260  305 PHE A CD2 
4714 C CE1 . PHE A 305 ? 0.69700 0.64030 0.67520 0.06620  -0.01600 0.05950  305 PHE A CE1 
4715 C CE2 . PHE A 305 ? 0.67650 0.66270 0.67120 0.07410  -0.02400 0.04910  305 PHE A CE2 
4716 C CZ  . PHE A 305 ? 0.66660 0.63780 0.65390 0.07060  -0.01780 0.05900  305 PHE A CZ  
4726 N N   . TYR A 306 ? 0.68200 0.58060 0.65590 0.08040  -0.04510 0.04260  306 TYR A N   
4727 C CA  . TYR A 306 ? 0.68390 0.56420 0.65970 0.08630  -0.04870 0.04460  306 TYR A CA  
4728 C C   . TYR A 306 ? 0.70310 0.59510 0.70700 0.08910  -0.05070 0.03260  306 TYR A C   
4729 O O   . TYR A 306 ? 0.66960 0.59130 0.68750 0.08910  -0.05350 0.02160  306 TYR A O   
4730 C CB  . TYR A 306 ? 0.68730 0.56650 0.65130 0.09360  -0.05930 0.04610  306 TYR A CB  
4731 C CG  . TYR A 306 ? 0.72550 0.60040 0.66540 0.09210  -0.05890 0.05260  306 TYR A CG  
4732 C CD1 . TYR A 306 ? 0.65630 0.54940 0.59600 0.08670  -0.05890 0.04700  306 TYR A CD1 
4733 C CD2 . TYR A 306 ? 0.73370 0.58790 0.65280 0.09640  -0.05780 0.06390  306 TYR A CD2 
4734 C CE1 . TYR A 306 ? 0.69780 0.58930 0.62170 0.08510  -0.05850 0.04830  306 TYR A CE1 
4735 C CE2 . TYR A 306 ? 0.71630 0.57330 0.61500 0.09610  -0.05810 0.06570  306 TYR A CE2 
4736 C CZ  . TYR A 306 ? 0.73540 0.61130 0.63880 0.09020  -0.05890 0.05590  306 TYR A CZ  
4737 O OH  . TYR A 306 ? 0.72300 0.60380 0.61220 0.08950  -0.05920 0.05330  306 TYR A OH  
4747 N N   . LYS A 307 ? 0.75190 0.62170 0.76570 0.09160  -0.04840 0.03470  307 LYS A N   
4748 C CA  . LYS A 307 ? 0.76490 0.64380 0.81130 0.09490  -0.05090 0.02010  307 LYS A CA  
4749 C C   . LYS A 307 ? 0.77100 0.65760 0.82370 0.10440  -0.06420 0.01420  307 LYS A C   
4750 O O   . LYS A 307 ? 0.76920 0.64490 0.80090 0.10960  -0.07040 0.02420  307 LYS A O   
4751 C CB  . LYS A 307 ? 0.87640 0.72510 0.93690 0.09300  -0.04160 0.02430  307 LYS A CB  
4752 C CG  . LYS A 307 ? 0.96660 0.81860 1.03590 0.08370  -0.02890 0.02000  307 LYS A CG  
4753 C CD  . LYS A 307 ? 1.24010 1.05520 1.30770 0.07880  -0.01610 0.03350  307 LYS A CD  
4754 C CE  . LYS A 307 ? 1.37230 1.17540 1.40400 0.07420  -0.00980 0.05070  307 LYS A CE  
4755 N NZ  . LYS A 307 ? 1.41060 1.19020 1.44460 0.06620  0.00620  0.05870  307 LYS A NZ  
4769 N N   . GLU A 308 ? 0.72870 0.63850 0.81210 0.10760  -0.06910 -0.00480 308 GLU A N   
4770 C CA  . GLU A 308 ? 0.74520 0.66830 0.83880 0.11680  -0.08210 -0.01460 308 GLU A CA  
4771 C C   . GLU A 308 ? 0.74330 0.68720 0.87780 0.12010  -0.08500 -0.03780 308 GLU A C   
4772 O O   . GLU A 308 ? 0.70620 0.66650 0.85850 0.11490  -0.07800 -0.04900 308 GLU A O   
4773 C CB  . GLU A 308 ? 0.74530 0.69950 0.82310 0.11590  -0.08800 -0.01720 308 GLU A CB  
4774 C CG  . GLU A 308 ? 0.75680 0.72780 0.84330 0.12490  -0.10140 -0.02830 308 GLU A CG  
4775 C CD  . GLU A 308 ? 0.81280 0.75110 0.88960 0.13480  -0.10840 -0.01790 308 GLU A CD  
4776 O OE1 . GLU A 308 ? 0.79460 0.71190 0.89080 0.14150  -0.10980 -0.01910 308 GLU A OE1 
4777 O OE2 . GLU A 308 ? 0.77550 0.71030 0.82690 0.13680  -0.11230 -0.00880 308 GLU A OE2 
4784 N N   . ASN A 309 ? 0.73940 0.68490 0.89050 0.12980  -0.09600 -0.04720 309 ASN A N   
4785 C CA  . ASN A 309 ? 0.75910 0.73240 0.95200 0.13440  -0.10140 -0.07440 309 ASN A CA  
4786 C C   . ASN A 309 ? 0.76250 0.76110 0.95930 0.14330  -0.11580 -0.08610 309 ASN A C   
4787 O O   . ASN A 309 ? 0.74020 0.78660 0.94630 0.14250  -0.11950 -0.10410 309 ASN A O   
4788 C CB  . ASN A 309 ? 0.81110 0.75050 1.03650 0.13730  -0.09760 -0.07760 309 ASN A CB  
4789 C CG  . ASN A 309 ? 0.98200 0.86880 1.18830 0.14310  -0.09730 -0.05120 309 ASN A CG  
4790 O OD1 . ASN A 309 ? 0.96040 0.84390 1.15040 0.15270  -0.10840 -0.04440 309 ASN A OD1 
4791 N ND2 . ASN A 309 ? 1.03640 0.88480 1.24460 0.13780  -0.08420 -0.03640 309 ASN A ND2 
4798 N N   . SER A 310 ? 0.81480 0.78440 1.00360 0.15270  -0.12360 -0.07560 310 SER A N   
4799 C CA  . SER A 310 ? 0.79500 0.78770 0.98730 0.16230  -0.13800 -0.08730 310 SER A CA  
4800 C C   . SER A 310 ? 0.80320 0.76350 0.96620 0.17070  -0.14380 -0.06630 310 SER A C   
4801 O O   . SER A 310 ? 0.83390 0.75050 0.99350 0.17650  -0.14120 -0.04910 310 SER A O   
4802 C CB  . SER A 310 ? 0.81050 0.81530 1.04880 0.17200  -0.14660 -0.11270 310 SER A CB  
4803 O OG  . SER A 310 ? 0.83870 0.88340 1.08430 0.17840  -0.15930 -0.13150 310 SER A OG  
4810 N N   . TYR A 311 ? 0.80260 0.78660 0.94530 0.17160  -0.15080 -0.06790 311 TYR A N   
4811 C CA  . TYR A 311 ? 0.77240 0.73700 0.88770 0.18100  -0.15810 -0.05310 311 TYR A CA  
4812 C C   . TYR A 311 ? 0.83020 0.82990 0.95310 0.18930  -0.17260 -0.07210 311 TYR A C   
4813 O O   . TYR A 311 ? 0.77140 0.81310 0.90540 0.18130  -0.17230 -0.08990 311 TYR A O   
4814 C CB  . TYR A 311 ? 0.78070 0.73730 0.85890 0.17090  -0.14910 -0.03490 311 TYR A CB  
4815 C CG  . TYR A 311 ? 0.84860 0.80590 0.90100 0.17940  -0.15810 -0.02910 311 TYR A CG  
4816 C CD1 . TYR A 311 ? 0.84490 0.76930 0.87770 0.19250  -0.16190 -0.01050 311 TYR A CD1 
4817 C CD2 . TYR A 311 ? 0.85260 0.84620 0.90140 0.17470  -0.16220 -0.04270 311 TYR A CD2 
4818 C CE1 . TYR A 311 ? 0.88500 0.81700 0.89410 0.20250  -0.17140 -0.00790 311 TYR A CE1 
4819 C CE2 . TYR A 311 ? 0.81640 0.81570 0.84620 0.18260  -0.17070 -0.04230 311 TYR A CE2 
4820 C CZ  . TYR A 311 ? 0.92270 0.89330 0.93200 0.19730  -0.17630 -0.02610 311 TYR A CZ  
4821 O OH  . TYR A 311 ? 0.92390 0.90680 0.91390 0.20720  -0.18590 -0.02820 311 TYR A OH  
4831 N N   . THR A 312 ? 0.84210 0.82630 0.95860 0.20610  -0.18490 -0.06750 312 THR A N   
4832 C CA  . THR A 312 ? 0.83970 0.85650 0.96260 0.21620  -0.20000 -0.08620 312 THR A CA  
4833 C C   . THR A 312 ? 0.86450 0.86680 0.95620 0.22860  -0.20790 -0.07190 312 THR A C   
4834 O O   . THR A 312 ? 0.90240 0.86510 0.97960 0.24000  -0.20820 -0.04990 312 THR A O   
4835 C CB  . THR A 312 ? 0.82860 0.85190 0.98950 0.23020  -0.21190 -0.10520 312 THR A CB  
4836 O OG1 . THR A 312 ? 0.84280 0.88120 1.03380 0.21970  -0.20410 -0.11990 312 THR A OG1 
4837 C CG2 . THR A 312 ? 0.82130 0.88670 0.99160 0.23880  -0.22690 -0.12900 312 THR A CG2 
4845 N N   . THR A 313 ? 0.90300 0.93990 0.98560 0.22660  -0.21350 -0.08480 313 THR A N   
4846 C CA  . THR A 313 ? 0.91800 0.95130 0.97110 0.23710  -0.22060 -0.07610 313 THR A CA  
4847 C C   . THR A 313 ? 0.97520 1.00520 1.03270 0.26370  -0.23930 -0.07940 313 THR A C   
4848 O O   . THR A 313 ? 0.96530 1.00980 1.05300 0.27180  -0.24900 -0.09780 313 THR A O   
4849 C CB  . THR A 313 ? 0.92160 0.99570 0.97070 0.22520  -0.21950 -0.09320 313 THR A CB  
4850 O OG1 . THR A 313 ? 1.02780 1.10570 1.05330 0.23780  -0.22880 -0.09120 313 THR A OG1 
4851 C CG2 . THR A 313 ? 0.89670 1.01430 0.97690 0.22380  -0.22670 -0.12260 313 THR A CG2 
4859 N N   . THR A 314 ? 1.08280 1.09550 1.10940 0.27870  -0.24480 -0.06160 314 THR A N   
4860 C CA  . THR A 314 ? 1.10030 1.11470 1.12400 0.30710  -0.26390 -0.06280 314 THR A CA  
4861 C C   . THR A 314 ? 1.17380 1.23540 1.19110 0.31290  -0.27650 -0.08620 314 THR A C   
4862 O O   . THR A 314 ? 1.17050 1.24340 1.18750 0.33780  -0.29460 -0.09280 314 THR A O   
4863 C CB  . THR A 314 ? 1.12730 1.09910 1.11920 0.32400  -0.26310 -0.02780 314 THR A CB  
4864 O OG1 . THR A 314 ? 1.20000 1.17860 1.15610 0.31700  -0.25640 -0.01810 314 THR A OG1 
4865 C CG2 . THR A 314 ? 1.09220 1.01620 1.09480 0.31680  -0.24870 -0.00560 314 THR A CG2 
4873 N N   . ILE A 315 ? 1.21810 1.30760 1.23300 0.29110  -0.26700 -0.09940 315 ILE A N   
4874 C CA  . ILE A 315 ? 1.21240 1.34810 1.22740 0.29320  -0.27620 -0.12480 315 ILE A CA  
4875 C C   . ILE A 315 ? 1.22420 1.39570 1.27330 0.29890  -0.28860 -0.15500 315 ILE A C   
4876 O O   . ILE A 315 ? 1.14360 1.31560 1.21940 0.28950  -0.28390 -0.16200 315 ILE A O   
4877 C CB  . ILE A 315 ? 1.19270 1.34460 1.20490 0.26570  -0.25990 -0.13120 315 ILE A CB  
4878 C CG1 . ILE A 315 ? 1.26230 1.39870 1.23970 0.26790  -0.25550 -0.11340 315 ILE A CG1 
4879 C CG2 . ILE A 315 ? 1.13810 1.34240 1.17250 0.25800  -0.26390 -0.16560 315 ILE A CG2 
4880 C CD1 . ILE A 315 ? 1.25120 1.33790 1.20800 0.26670  -0.24450 -0.07930 315 ILE A CD1 
4892 N N   . LYS A 316 ? 1.21640 1.42300 1.26580 0.31510  -0.30480 -0.17570 316 LYS A N   
4893 C CA  . LYS A 316 ? 1.16010 1.40710 1.24220 0.32160  -0.31760 -0.20810 316 LYS A CA  
4894 C C   . LYS A 316 ? 1.15140 1.45110 1.24000 0.31590  -0.32130 -0.23880 316 LYS A C   
4895 O O   . LYS A 316 ? 1.06950 1.39300 1.17440 0.28930  -0.30690 -0.25330 316 LYS A O   
4896 C CB  . LYS A 316 ? 1.12340 1.35840 1.20770 0.35560  -0.33870 -0.20500 316 LYS A CB  
# 
