data_9F7P
# 
_entry.id   9F7P 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9F7P         pdb_00009f7p 10.2210/pdb9f7p/pdb 
WWPDB D_1292136911 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-05-14 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9F7P 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-04 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              acamara@ual.es 
_pdbx_contact_author.name_first         ana 
_pdbx_contact_author.name_last          camara-artigas 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2197-726X 
# 
_audit_author.name               'Camara-Artigas, A.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0003-2197-726X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'SARS-CoV-2 papain-like protease (PLpro) C112S mutant' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
_citation_author.citation_id        primary 
_citation_author.name               'Camara-Artigas, A.' 
_citation_author.ordinal            1 
_citation_author.identifier_ORCID   0000-0003-2197-726X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Replicase polyprotein 1ab' 36912.844 1   3.4.19.12,3.4.22.- C112S ? ? 
2 non-polymer syn 'ZINC ION'                  65.409    1   ?                  ?     ? ? 
3 non-polymer syn 'MALONATE ION'              102.046   2   ?                  ?     ? ? 
4 non-polymer syn 'DI(HYDROXYETHYL)ETHER'     106.120   1   ?                  ?     ? ? 
5 non-polymer syn 'SODIUM ION'                22.990    2   ?                  ?     ? ? 
6 non-polymer syn 'CHLORIDE ION'              35.453    2   ?                  ?     ? ? 
7 water       nat water                       18.015    338 ?                  ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSF
LGRYMSALNHTKKWKYPQVNGLTSIKWADNNSYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV
GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQES
PFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTH
HHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSF
LGRYMSALNHTKKWKYPQVNGLTSIKWADNNSYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV
GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQES
PFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTH
HHHHH
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'ZINC ION'              ZN  
3 'MALONATE ION'          MLI 
4 'DI(HYDROXYETHYL)ETHER' PEG 
5 'SODIUM ION'            NA  
6 'CHLORIDE ION'          CL  
7 water                   HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   VAL n 
1 4   ARG n 
1 5   THR n 
1 6   ILE n 
1 7   LYS n 
1 8   VAL n 
1 9   PHE n 
1 10  THR n 
1 11  THR n 
1 12  VAL n 
1 13  ASP n 
1 14  ASN n 
1 15  ILE n 
1 16  ASN n 
1 17  LEU n 
1 18  HIS n 
1 19  THR n 
1 20  GLN n 
1 21  VAL n 
1 22  VAL n 
1 23  ASP n 
1 24  MET n 
1 25  SER n 
1 26  MET n 
1 27  THR n 
1 28  TYR n 
1 29  GLY n 
1 30  GLN n 
1 31  GLN n 
1 32  PHE n 
1 33  GLY n 
1 34  PRO n 
1 35  THR n 
1 36  TYR n 
1 37  LEU n 
1 38  ASP n 
1 39  GLY n 
1 40  ALA n 
1 41  ASP n 
1 42  VAL n 
1 43  THR n 
1 44  LYS n 
1 45  ILE n 
1 46  LYS n 
1 47  PRO n 
1 48  HIS n 
1 49  ASN n 
1 50  SER n 
1 51  HIS n 
1 52  GLU n 
1 53  GLY n 
1 54  LYS n 
1 55  THR n 
1 56  PHE n 
1 57  TYR n 
1 58  VAL n 
1 59  LEU n 
1 60  PRO n 
1 61  ASN n 
1 62  ASP n 
1 63  ASP n 
1 64  THR n 
1 65  LEU n 
1 66  ARG n 
1 67  VAL n 
1 68  GLU n 
1 69  ALA n 
1 70  PHE n 
1 71  GLU n 
1 72  TYR n 
1 73  TYR n 
1 74  HIS n 
1 75  THR n 
1 76  THR n 
1 77  ASP n 
1 78  PRO n 
1 79  SER n 
1 80  PHE n 
1 81  LEU n 
1 82  GLY n 
1 83  ARG n 
1 84  TYR n 
1 85  MET n 
1 86  SER n 
1 87  ALA n 
1 88  LEU n 
1 89  ASN n 
1 90  HIS n 
1 91  THR n 
1 92  LYS n 
1 93  LYS n 
1 94  TRP n 
1 95  LYS n 
1 96  TYR n 
1 97  PRO n 
1 98  GLN n 
1 99  VAL n 
1 100 ASN n 
1 101 GLY n 
1 102 LEU n 
1 103 THR n 
1 104 SER n 
1 105 ILE n 
1 106 LYS n 
1 107 TRP n 
1 108 ALA n 
1 109 ASP n 
1 110 ASN n 
1 111 ASN n 
1 112 SER n 
1 113 TYR n 
1 114 LEU n 
1 115 ALA n 
1 116 THR n 
1 117 ALA n 
1 118 LEU n 
1 119 LEU n 
1 120 THR n 
1 121 LEU n 
1 122 GLN n 
1 123 GLN n 
1 124 ILE n 
1 125 GLU n 
1 126 LEU n 
1 127 LYS n 
1 128 PHE n 
1 129 ASN n 
1 130 PRO n 
1 131 PRO n 
1 132 ALA n 
1 133 LEU n 
1 134 GLN n 
1 135 ASP n 
1 136 ALA n 
1 137 TYR n 
1 138 TYR n 
1 139 ARG n 
1 140 ALA n 
1 141 ARG n 
1 142 ALA n 
1 143 GLY n 
1 144 GLU n 
1 145 ALA n 
1 146 ALA n 
1 147 ASN n 
1 148 PHE n 
1 149 CYS n 
1 150 ALA n 
1 151 LEU n 
1 152 ILE n 
1 153 LEU n 
1 154 ALA n 
1 155 TYR n 
1 156 CYS n 
1 157 ASN n 
1 158 LYS n 
1 159 THR n 
1 160 VAL n 
1 161 GLY n 
1 162 GLU n 
1 163 LEU n 
1 164 GLY n 
1 165 ASP n 
1 166 VAL n 
1 167 ARG n 
1 168 GLU n 
1 169 THR n 
1 170 MET n 
1 171 SER n 
1 172 TYR n 
1 173 LEU n 
1 174 PHE n 
1 175 GLN n 
1 176 HIS n 
1 177 ALA n 
1 178 ASN n 
1 179 LEU n 
1 180 ASP n 
1 181 SER n 
1 182 CYS n 
1 183 LYS n 
1 184 ARG n 
1 185 VAL n 
1 186 LEU n 
1 187 ASN n 
1 188 VAL n 
1 189 VAL n 
1 190 CYS n 
1 191 LYS n 
1 192 THR n 
1 193 CYS n 
1 194 GLY n 
1 195 GLN n 
1 196 GLN n 
1 197 GLN n 
1 198 THR n 
1 199 THR n 
1 200 LEU n 
1 201 LYS n 
1 202 GLY n 
1 203 VAL n 
1 204 GLU n 
1 205 ALA n 
1 206 VAL n 
1 207 MET n 
1 208 TYR n 
1 209 MET n 
1 210 GLY n 
1 211 THR n 
1 212 LEU n 
1 213 SER n 
1 214 TYR n 
1 215 GLU n 
1 216 GLN n 
1 217 PHE n 
1 218 LYS n 
1 219 LYS n 
1 220 GLY n 
1 221 VAL n 
1 222 GLN n 
1 223 ILE n 
1 224 PRO n 
1 225 CYS n 
1 226 THR n 
1 227 CYS n 
1 228 GLY n 
1 229 LYS n 
1 230 GLN n 
1 231 ALA n 
1 232 THR n 
1 233 LYS n 
1 234 TYR n 
1 235 LEU n 
1 236 VAL n 
1 237 GLN n 
1 238 GLN n 
1 239 GLU n 
1 240 SER n 
1 241 PRO n 
1 242 PHE n 
1 243 VAL n 
1 244 MET n 
1 245 MET n 
1 246 SER n 
1 247 ALA n 
1 248 PRO n 
1 249 PRO n 
1 250 ALA n 
1 251 GLN n 
1 252 TYR n 
1 253 GLU n 
1 254 LEU n 
1 255 LYS n 
1 256 HIS n 
1 257 GLY n 
1 258 THR n 
1 259 PHE n 
1 260 THR n 
1 261 CYS n 
1 262 ALA n 
1 263 SER n 
1 264 GLU n 
1 265 TYR n 
1 266 THR n 
1 267 GLY n 
1 268 ASN n 
1 269 TYR n 
1 270 GLN n 
1 271 CYS n 
1 272 GLY n 
1 273 HIS n 
1 274 TYR n 
1 275 LYS n 
1 276 HIS n 
1 277 ILE n 
1 278 THR n 
1 279 SER n 
1 280 LYS n 
1 281 GLU n 
1 282 THR n 
1 283 LEU n 
1 284 TYR n 
1 285 CYS n 
1 286 ILE n 
1 287 ASP n 
1 288 GLY n 
1 289 ALA n 
1 290 LEU n 
1 291 LEU n 
1 292 THR n 
1 293 LYS n 
1 294 SER n 
1 295 SER n 
1 296 GLU n 
1 297 TYR n 
1 298 LYS n 
1 299 GLY n 
1 300 PRO n 
1 301 ILE n 
1 302 THR n 
1 303 ASP n 
1 304 VAL n 
1 305 PHE n 
1 306 TYR n 
1 307 LYS n 
1 308 GLU n 
1 309 ASN n 
1 310 SER n 
1 311 TYR n 
1 312 THR n 
1 313 THR n 
1 314 THR n 
1 315 ILE n 
1 316 LYS n 
1 317 PRO n 
1 318 VAL n 
1 319 THR n 
1 320 HIS n 
1 321 HIS n 
1 322 HIS n 
1 323 HIS n 
1 324 HIS n 
1 325 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   325 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'rep, 1a-1b' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Severe acute respiratory syndrome coronavirus 2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2697049 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                 ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE              ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'         ? 'C4 H7 N O4'     133.103 
CL  non-polymer         . 'CHLORIDE ION'          ? 'Cl -1'          35.453  
CYS 'L-peptide linking' y CYSTEINE                ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE               ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'         ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                 ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE               ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                   ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE              ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                 ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                  ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE              ? 'C5 H11 N O2 S'  149.211 
MLI non-polymer         . 'MALONATE ION'          ? 'C3 H2 O4 -2'    102.046 
NA  non-polymer         . 'SODIUM ION'            ? 'Na 1'           22.990  
PEG non-polymer         . 'DI(HYDROXYETHYL)ETHER' ? 'C4 H10 O3'      106.120 
PHE 'L-peptide linking' y PHENYLALANINE           ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                 ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                  ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE               ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN              ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                  ? 'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'              ? 'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLU 2   2   ?   ?   ?   A . n 
A 1 3   VAL 3   3   3   VAL VAL A . n 
A 1 4   ARG 4   4   4   ARG ARG A . n 
A 1 5   THR 5   5   5   THR THR A . n 
A 1 6   ILE 6   6   6   ILE ILE A . n 
A 1 7   LYS 7   7   7   LYS LYS A . n 
A 1 8   VAL 8   8   8   VAL VAL A . n 
A 1 9   PHE 9   9   9   PHE PHE A . n 
A 1 10  THR 10  10  10  THR THR A . n 
A 1 11  THR 11  11  11  THR THR A . n 
A 1 12  VAL 12  12  12  VAL VAL A . n 
A 1 13  ASP 13  13  13  ASP ASP A . n 
A 1 14  ASN 14  14  14  ASN ASN A . n 
A 1 15  ILE 15  15  15  ILE ILE A . n 
A 1 16  ASN 16  16  16  ASN ASN A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  HIS 18  18  18  HIS HIS A . n 
A 1 19  THR 19  19  19  THR THR A . n 
A 1 20  GLN 20  20  20  GLN GLN A . n 
A 1 21  VAL 21  21  21  VAL VAL A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  ASP 23  23  23  ASP ASP A . n 
A 1 24  MET 24  24  24  MET MET A . n 
A 1 25  SER 25  25  25  SER SER A . n 
A 1 26  MET 26  26  26  MET MET A . n 
A 1 27  THR 27  27  27  THR THR A . n 
A 1 28  TYR 28  28  28  TYR TYR A . n 
A 1 29  GLY 29  29  29  GLY GLY A . n 
A 1 30  GLN 30  30  30  GLN GLN A . n 
A 1 31  GLN 31  31  31  GLN GLN A . n 
A 1 32  PHE 32  32  32  PHE PHE A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  PRO 34  34  34  PRO PRO A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  TYR 36  36  36  TYR TYR A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  ASP 38  38  38  ASP ASP A . n 
A 1 39  GLY 39  39  39  GLY GLY A . n 
A 1 40  ALA 40  40  40  ALA ALA A . n 
A 1 41  ASP 41  41  41  ASP ASP A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  THR 43  43  43  THR THR A . n 
A 1 44  LYS 44  44  44  LYS LYS A . n 
A 1 45  ILE 45  45  45  ILE ILE A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  HIS 48  48  48  HIS HIS A . n 
A 1 49  ASN 49  49  49  ASN ASN A . n 
A 1 50  SER 50  50  50  SER SER A . n 
A 1 51  HIS 51  51  51  HIS HIS A . n 
A 1 52  GLU 52  52  52  GLU GLU A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  LYS 54  54  54  LYS LYS A . n 
A 1 55  THR 55  55  55  THR THR A . n 
A 1 56  PHE 56  56  56  PHE PHE A . n 
A 1 57  TYR 57  57  57  TYR TYR A . n 
A 1 58  VAL 58  58  58  VAL VAL A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  PRO 60  60  60  PRO PRO A . n 
A 1 61  ASN 61  61  61  ASN ASN A . n 
A 1 62  ASP 62  62  62  ASP ASP A . n 
A 1 63  ASP 63  63  63  ASP ASP A . n 
A 1 64  THR 64  64  64  THR THR A . n 
A 1 65  LEU 65  65  65  LEU LEU A . n 
A 1 66  ARG 66  66  66  ARG ARG A . n 
A 1 67  VAL 67  67  67  VAL VAL A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  PHE 70  70  70  PHE PHE A . n 
A 1 71  GLU 71  71  71  GLU GLU A . n 
A 1 72  TYR 72  72  72  TYR TYR A . n 
A 1 73  TYR 73  73  73  TYR TYR A . n 
A 1 74  HIS 74  74  74  HIS HIS A . n 
A 1 75  THR 75  75  75  THR THR A . n 
A 1 76  THR 76  76  76  THR THR A . n 
A 1 77  ASP 77  77  77  ASP ASP A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  PHE 80  80  80  PHE PHE A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  GLY 82  82  82  GLY GLY A . n 
A 1 83  ARG 83  83  83  ARG ARG A . n 
A 1 84  TYR 84  84  84  TYR TYR A . n 
A 1 85  MET 85  85  85  MET MET A . n 
A 1 86  SER 86  86  86  SER SER A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  ASN 89  89  89  ASN ASN A . n 
A 1 90  HIS 90  90  90  HIS HIS A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  LYS 92  92  92  LYS LYS A . n 
A 1 93  LYS 93  93  93  LYS LYS A . n 
A 1 94  TRP 94  94  94  TRP TRP A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  TYR 96  96  96  TYR TYR A . n 
A 1 97  PRO 97  97  97  PRO PRO A . n 
A 1 98  GLN 98  98  98  GLN GLN A . n 
A 1 99  VAL 99  99  99  VAL VAL A . n 
A 1 100 ASN 100 100 100 ASN ASN A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 LEU 102 102 102 LEU LEU A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 SER 104 104 104 SER SER A . n 
A 1 105 ILE 105 105 105 ILE ILE A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 TRP 107 107 107 TRP TRP A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 ASP 109 109 109 ASP ASP A . n 
A 1 110 ASN 110 110 110 ASN ASN A . n 
A 1 111 ASN 111 111 111 ASN ASN A . n 
A 1 112 SER 112 112 112 SER SER A . n 
A 1 113 TYR 113 113 113 TYR TYR A . n 
A 1 114 LEU 114 114 114 LEU LEU A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 THR 116 116 116 THR THR A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 GLN 122 122 122 GLN GLN A . n 
A 1 123 GLN 123 123 123 GLN GLN A . n 
A 1 124 ILE 124 124 124 ILE ILE A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 LYS 127 127 127 LYS LYS A . n 
A 1 128 PHE 128 128 128 PHE PHE A . n 
A 1 129 ASN 129 129 129 ASN ASN A . n 
A 1 130 PRO 130 130 130 PRO PRO A . n 
A 1 131 PRO 131 131 131 PRO PRO A . n 
A 1 132 ALA 132 132 132 ALA ALA A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 GLN 134 134 134 GLN GLN A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 ALA 136 136 136 ALA ALA A . n 
A 1 137 TYR 137 137 137 TYR TYR A . n 
A 1 138 TYR 138 138 138 TYR TYR A . n 
A 1 139 ARG 139 139 139 ARG ARG A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 ARG 141 141 141 ARG ARG A . n 
A 1 142 ALA 142 142 142 ALA ALA A . n 
A 1 143 GLY 143 143 143 GLY GLY A . n 
A 1 144 GLU 144 144 144 GLU GLU A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 ASN 147 147 147 ASN ASN A . n 
A 1 148 PHE 148 148 148 PHE PHE A . n 
A 1 149 CYS 149 149 149 CYS CYS A . n 
A 1 150 ALA 150 150 150 ALA ALA A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 TYR 155 155 155 TYR TYR A . n 
A 1 156 CYS 156 156 156 CYS CYS A . n 
A 1 157 ASN 157 157 157 ASN ASN A . n 
A 1 158 LYS 158 158 158 LYS LYS A . n 
A 1 159 THR 159 159 159 THR THR A . n 
A 1 160 VAL 160 160 160 VAL VAL A . n 
A 1 161 GLY 161 161 161 GLY GLY A . n 
A 1 162 GLU 162 162 162 GLU GLU A . n 
A 1 163 LEU 163 163 163 LEU LEU A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 ARG 167 167 167 ARG ARG A . n 
A 1 168 GLU 168 168 168 GLU GLU A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 MET 170 170 170 MET MET A . n 
A 1 171 SER 171 171 171 SER SER A . n 
A 1 172 TYR 172 172 172 TYR TYR A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 PHE 174 174 174 PHE PHE A . n 
A 1 175 GLN 175 175 175 GLN GLN A . n 
A 1 176 HIS 176 176 176 HIS HIS A . n 
A 1 177 ALA 177 177 177 ALA ALA A . n 
A 1 178 ASN 178 178 178 ASN ASN A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 ASP 180 180 180 ASP ASP A . n 
A 1 181 SER 181 181 181 SER SER A . n 
A 1 182 CYS 182 182 182 CYS CYS A . n 
A 1 183 LYS 183 183 183 LYS LYS A . n 
A 1 184 ARG 184 184 184 ARG ARG A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 ASN 187 187 187 ASN ASN A . n 
A 1 188 VAL 188 188 188 VAL VAL A . n 
A 1 189 VAL 189 189 189 VAL VAL A . n 
A 1 190 CYS 190 190 190 CYS CYS A . n 
A 1 191 LYS 191 191 191 LYS LYS A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 CYS 193 193 193 CYS CYS A . n 
A 1 194 GLY 194 194 194 GLY GLY A . n 
A 1 195 GLN 195 195 195 GLN GLN A . n 
A 1 196 GLN 196 196 196 GLN GLN A . n 
A 1 197 GLN 197 197 197 GLN GLN A . n 
A 1 198 THR 198 198 198 THR THR A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 LEU 200 200 200 LEU LEU A . n 
A 1 201 LYS 201 201 201 LYS LYS A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 VAL 203 203 203 VAL VAL A . n 
A 1 204 GLU 204 204 204 GLU GLU A . n 
A 1 205 ALA 205 205 205 ALA ALA A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 MET 207 207 207 MET MET A . n 
A 1 208 TYR 208 208 208 TYR TYR A . n 
A 1 209 MET 209 209 209 MET MET A . n 
A 1 210 GLY 210 210 210 GLY GLY A . n 
A 1 211 THR 211 211 211 THR THR A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 SER 213 213 213 SER SER A . n 
A 1 214 TYR 214 214 214 TYR TYR A . n 
A 1 215 GLU 215 215 215 GLU GLU A . n 
A 1 216 GLN 216 216 216 GLN GLN A . n 
A 1 217 PHE 217 217 217 PHE PHE A . n 
A 1 218 LYS 218 218 218 LYS LYS A . n 
A 1 219 LYS 219 219 219 LYS LYS A . n 
A 1 220 GLY 220 220 220 GLY GLY A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 GLN 222 222 222 GLN GLN A . n 
A 1 223 ILE 223 223 223 ILE ILE A . n 
A 1 224 PRO 224 224 224 PRO PRO A . n 
A 1 225 CYS 225 225 225 CYS CYS A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 CYS 227 227 227 CYS CYS A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 LYS 229 229 229 LYS LYS A . n 
A 1 230 GLN 230 230 230 GLN GLN A . n 
A 1 231 ALA 231 231 231 ALA ALA A . n 
A 1 232 THR 232 232 232 THR THR A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 TYR 234 234 234 TYR TYR A . n 
A 1 235 LEU 235 235 235 LEU LEU A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 GLN 237 237 237 GLN GLN A . n 
A 1 238 GLN 238 238 238 GLN GLN A . n 
A 1 239 GLU 239 239 239 GLU GLU A . n 
A 1 240 SER 240 240 240 SER SER A . n 
A 1 241 PRO 241 241 241 PRO PRO A . n 
A 1 242 PHE 242 242 242 PHE PHE A . n 
A 1 243 VAL 243 243 243 VAL VAL A . n 
A 1 244 MET 244 244 244 MET MET A . n 
A 1 245 MET 245 245 245 MET MET A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 ALA 247 247 247 ALA ALA A . n 
A 1 248 PRO 248 248 248 PRO PRO A . n 
A 1 249 PRO 249 249 249 PRO PRO A . n 
A 1 250 ALA 250 250 250 ALA ALA A . n 
A 1 251 GLN 251 251 251 GLN GLN A . n 
A 1 252 TYR 252 252 252 TYR TYR A . n 
A 1 253 GLU 253 253 253 GLU GLU A . n 
A 1 254 LEU 254 254 254 LEU LEU A . n 
A 1 255 LYS 255 255 255 LYS LYS A . n 
A 1 256 HIS 256 256 256 HIS HIS A . n 
A 1 257 GLY 257 257 257 GLY GLY A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 PHE 259 259 259 PHE PHE A . n 
A 1 260 THR 260 260 260 THR THR A . n 
A 1 261 CYS 261 261 261 CYS CYS A . n 
A 1 262 ALA 262 262 262 ALA ALA A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 GLU 264 264 264 GLU GLU A . n 
A 1 265 TYR 265 265 265 TYR TYR A . n 
A 1 266 THR 266 266 266 THR THR A . n 
A 1 267 GLY 267 267 267 GLY GLY A . n 
A 1 268 ASN 268 268 268 ASN ASN A . n 
A 1 269 TYR 269 269 269 TYR TYR A . n 
A 1 270 GLN 270 270 270 GLN GLN A . n 
A 1 271 CYS 271 271 271 CYS CYS A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 HIS 273 273 273 HIS HIS A . n 
A 1 274 TYR 274 274 274 TYR TYR A . n 
A 1 275 LYS 275 275 275 LYS LYS A . n 
A 1 276 HIS 276 276 276 HIS HIS A . n 
A 1 277 ILE 277 277 277 ILE ILE A . n 
A 1 278 THR 278 278 278 THR THR A . n 
A 1 279 SER 279 279 279 SER SER A . n 
A 1 280 LYS 280 280 280 LYS LYS A . n 
A 1 281 GLU 281 281 281 GLU GLU A . n 
A 1 282 THR 282 282 282 THR THR A . n 
A 1 283 LEU 283 283 283 LEU LEU A . n 
A 1 284 TYR 284 284 284 TYR TYR A . n 
A 1 285 CYS 285 285 285 CYS CYS A . n 
A 1 286 ILE 286 286 286 ILE ILE A . n 
A 1 287 ASP 287 287 287 ASP ASP A . n 
A 1 288 GLY 288 288 288 GLY GLY A . n 
A 1 289 ALA 289 289 289 ALA ALA A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 LEU 291 291 291 LEU LEU A . n 
A 1 292 THR 292 292 292 THR THR A . n 
A 1 293 LYS 293 293 293 LYS LYS A . n 
A 1 294 SER 294 294 294 SER SER A . n 
A 1 295 SER 295 295 295 SER SER A . n 
A 1 296 GLU 296 296 296 GLU GLU A . n 
A 1 297 TYR 297 297 297 TYR TYR A . n 
A 1 298 LYS 298 298 298 LYS LYS A . n 
A 1 299 GLY 299 299 299 GLY GLY A . n 
A 1 300 PRO 300 300 300 PRO PRO A . n 
A 1 301 ILE 301 301 301 ILE ILE A . n 
A 1 302 THR 302 302 302 THR THR A . n 
A 1 303 ASP 303 303 303 ASP ASP A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 PHE 305 305 305 PHE PHE A . n 
A 1 306 TYR 306 306 306 TYR TYR A . n 
A 1 307 LYS 307 307 307 LYS LYS A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 ASN 309 309 309 ASN ASN A . n 
A 1 310 SER 310 310 310 SER SER A . n 
A 1 311 TYR 311 311 311 TYR TYR A . n 
A 1 312 THR 312 312 312 THR THR A . n 
A 1 313 THR 313 313 313 THR THR A . n 
A 1 314 THR 314 314 314 THR THR A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 LYS 316 316 316 LYS LYS A . n 
A 1 317 PRO 317 317 317 PRO PRO A . n 
A 1 318 VAL 318 318 ?   ?   ?   A . n 
A 1 319 THR 319 319 ?   ?   ?   A . n 
A 1 320 HIS 320 320 ?   ?   ?   A . n 
A 1 321 HIS 321 321 ?   ?   ?   A . n 
A 1 322 HIS 322 322 ?   ?   ?   A . n 
A 1 323 HIS 323 323 ?   ?   ?   A . n 
A 1 324 HIS 324 324 ?   ?   ?   A . n 
A 1 325 HIS 325 325 ?   ?   ?   A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 ZN  1   401 401 ZN  ZN  A . 
C 3 MLI 1   402 402 MLI MLI A . 
D 4 PEG 1   403 403 PEG PEG A . 
E 3 MLI 1   404 405 MLI MLI A . 
F 5 NA  1   405 1   NA  NA  A . 
G 5 NA  1   406 2   NA  NA  A . 
H 6 CL  1   407 1   CL  CL  A . 
I 6 CL  1   408 2   CL  CL  A . 
J 7 HOH 1   501 164 HOH HOH A . 
J 7 HOH 2   502 234 HOH HOH A . 
J 7 HOH 3   503 45  HOH HOH A . 
J 7 HOH 4   504 215 HOH HOH A . 
J 7 HOH 5   505 138 HOH HOH A . 
J 7 HOH 6   506 162 HOH HOH A . 
J 7 HOH 7   507 95  HOH HOH A . 
J 7 HOH 8   508 130 HOH HOH A . 
J 7 HOH 9   509 239 HOH HOH A . 
J 7 HOH 10  510 76  HOH HOH A . 
J 7 HOH 11  511 178 HOH HOH A . 
J 7 HOH 12  512 315 HOH HOH A . 
J 7 HOH 13  513 5   HOH HOH A . 
J 7 HOH 14  514 15  HOH HOH A . 
J 7 HOH 15  515 242 HOH HOH A . 
J 7 HOH 16  516 150 HOH HOH A . 
J 7 HOH 17  517 97  HOH HOH A . 
J 7 HOH 18  518 300 HOH HOH A . 
J 7 HOH 19  519 262 HOH HOH A . 
J 7 HOH 20  520 182 HOH HOH A . 
J 7 HOH 21  521 87  HOH HOH A . 
J 7 HOH 22  522 231 HOH HOH A . 
J 7 HOH 23  523 197 HOH HOH A . 
J 7 HOH 24  524 82  HOH HOH A . 
J 7 HOH 25  525 3   HOH HOH A . 
J 7 HOH 26  526 152 HOH HOH A . 
J 7 HOH 27  527 159 HOH HOH A . 
J 7 HOH 28  528 7   HOH HOH A . 
J 7 HOH 29  529 47  HOH HOH A . 
J 7 HOH 30  530 187 HOH HOH A . 
J 7 HOH 31  531 92  HOH HOH A . 
J 7 HOH 32  532 305 HOH HOH A . 
J 7 HOH 33  533 103 HOH HOH A . 
J 7 HOH 34  534 88  HOH HOH A . 
J 7 HOH 35  535 155 HOH HOH A . 
J 7 HOH 36  536 158 HOH HOH A . 
J 7 HOH 37  537 142 HOH HOH A . 
J 7 HOH 38  538 71  HOH HOH A . 
J 7 HOH 39  539 237 HOH HOH A . 
J 7 HOH 40  540 200 HOH HOH A . 
J 7 HOH 41  541 101 HOH HOH A . 
J 7 HOH 42  542 79  HOH HOH A . 
J 7 HOH 43  543 264 HOH HOH A . 
J 7 HOH 44  544 81  HOH HOH A . 
J 7 HOH 45  545 29  HOH HOH A . 
J 7 HOH 46  546 25  HOH HOH A . 
J 7 HOH 47  547 13  HOH HOH A . 
J 7 HOH 48  548 128 HOH HOH A . 
J 7 HOH 49  549 114 HOH HOH A . 
J 7 HOH 50  550 17  HOH HOH A . 
J 7 HOH 51  551 19  HOH HOH A . 
J 7 HOH 52  552 54  HOH HOH A . 
J 7 HOH 53  553 308 HOH HOH A . 
J 7 HOH 54  554 244 HOH HOH A . 
J 7 HOH 55  555 240 HOH HOH A . 
J 7 HOH 56  556 283 HOH HOH A . 
J 7 HOH 57  557 43  HOH HOH A . 
J 7 HOH 58  558 202 HOH HOH A . 
J 7 HOH 59  559 111 HOH HOH A . 
J 7 HOH 60  560 273 HOH HOH A . 
J 7 HOH 61  561 121 HOH HOH A . 
J 7 HOH 62  562 2   HOH HOH A . 
J 7 HOH 63  563 177 HOH HOH A . 
J 7 HOH 64  564 37  HOH HOH A . 
J 7 HOH 65  565 126 HOH HOH A . 
J 7 HOH 66  566 73  HOH HOH A . 
J 7 HOH 67  567 217 HOH HOH A . 
J 7 HOH 68  568 113 HOH HOH A . 
J 7 HOH 69  569 170 HOH HOH A . 
J 7 HOH 70  570 330 HOH HOH A . 
J 7 HOH 71  571 124 HOH HOH A . 
J 7 HOH 72  572 85  HOH HOH A . 
J 7 HOH 73  573 66  HOH HOH A . 
J 7 HOH 74  574 68  HOH HOH A . 
J 7 HOH 75  575 218 HOH HOH A . 
J 7 HOH 76  576 46  HOH HOH A . 
J 7 HOH 77  577 65  HOH HOH A . 
J 7 HOH 78  578 99  HOH HOH A . 
J 7 HOH 79  579 243 HOH HOH A . 
J 7 HOH 80  580 286 HOH HOH A . 
J 7 HOH 81  581 252 HOH HOH A . 
J 7 HOH 82  582 34  HOH HOH A . 
J 7 HOH 83  583 28  HOH HOH A . 
J 7 HOH 84  584 36  HOH HOH A . 
J 7 HOH 85  585 270 HOH HOH A . 
J 7 HOH 86  586 64  HOH HOH A . 
J 7 HOH 87  587 176 HOH HOH A . 
J 7 HOH 88  588 27  HOH HOH A . 
J 7 HOH 89  589 129 HOH HOH A . 
J 7 HOH 90  590 57  HOH HOH A . 
J 7 HOH 91  591 309 HOH HOH A . 
J 7 HOH 92  592 194 HOH HOH A . 
J 7 HOH 93  593 181 HOH HOH A . 
J 7 HOH 94  594 259 HOH HOH A . 
J 7 HOH 95  595 175 HOH HOH A . 
J 7 HOH 96  596 296 HOH HOH A . 
J 7 HOH 97  597 56  HOH HOH A . 
J 7 HOH 98  598 39  HOH HOH A . 
J 7 HOH 99  599 55  HOH HOH A . 
J 7 HOH 100 600 322 HOH HOH A . 
J 7 HOH 101 601 86  HOH HOH A . 
J 7 HOH 102 602 96  HOH HOH A . 
J 7 HOH 103 603 89  HOH HOH A . 
J 7 HOH 104 604 33  HOH HOH A . 
J 7 HOH 105 605 108 HOH HOH A . 
J 7 HOH 106 606 261 HOH HOH A . 
J 7 HOH 107 607 148 HOH HOH A . 
J 7 HOH 108 608 91  HOH HOH A . 
J 7 HOH 109 609 26  HOH HOH A . 
J 7 HOH 110 610 186 HOH HOH A . 
J 7 HOH 111 611 249 HOH HOH A . 
J 7 HOH 112 612 59  HOH HOH A . 
J 7 HOH 113 613 70  HOH HOH A . 
J 7 HOH 114 614 10  HOH HOH A . 
J 7 HOH 115 615 149 HOH HOH A . 
J 7 HOH 116 616 123 HOH HOH A . 
J 7 HOH 117 617 306 HOH HOH A . 
J 7 HOH 118 618 14  HOH HOH A . 
J 7 HOH 119 619 4   HOH HOH A . 
J 7 HOH 120 620 93  HOH HOH A . 
J 7 HOH 121 621 30  HOH HOH A . 
J 7 HOH 122 622 12  HOH HOH A . 
J 7 HOH 123 623 77  HOH HOH A . 
J 7 HOH 124 624 319 HOH HOH A . 
J 7 HOH 125 625 21  HOH HOH A . 
J 7 HOH 126 626 102 HOH HOH A . 
J 7 HOH 127 627 233 HOH HOH A . 
J 7 HOH 128 628 320 HOH HOH A . 
J 7 HOH 129 629 18  HOH HOH A . 
J 7 HOH 130 630 140 HOH HOH A . 
J 7 HOH 131 631 78  HOH HOH A . 
J 7 HOH 132 632 72  HOH HOH A . 
J 7 HOH 133 633 147 HOH HOH A . 
J 7 HOH 134 634 61  HOH HOH A . 
J 7 HOH 135 635 141 HOH HOH A . 
J 7 HOH 136 636 24  HOH HOH A . 
J 7 HOH 137 637 80  HOH HOH A . 
J 7 HOH 138 638 248 HOH HOH A . 
J 7 HOH 139 639 49  HOH HOH A . 
J 7 HOH 140 640 6   HOH HOH A . 
J 7 HOH 141 641 265 HOH HOH A . 
J 7 HOH 142 642 23  HOH HOH A . 
J 7 HOH 143 643 90  HOH HOH A . 
J 7 HOH 144 644 238 HOH HOH A . 
J 7 HOH 145 645 245 HOH HOH A . 
J 7 HOH 146 646 67  HOH HOH A . 
J 7 HOH 147 647 241 HOH HOH A . 
J 7 HOH 148 648 8   HOH HOH A . 
J 7 HOH 149 649 133 HOH HOH A . 
J 7 HOH 150 650 206 HOH HOH A . 
J 7 HOH 151 651 287 HOH HOH A . 
J 7 HOH 152 652 104 HOH HOH A . 
J 7 HOH 153 653 122 HOH HOH A . 
J 7 HOH 154 654 9   HOH HOH A . 
J 7 HOH 155 655 151 HOH HOH A . 
J 7 HOH 156 656 280 HOH HOH A . 
J 7 HOH 157 657 222 HOH HOH A . 
J 7 HOH 158 658 16  HOH HOH A . 
J 7 HOH 159 659 288 HOH HOH A . 
J 7 HOH 160 660 254 HOH HOH A . 
J 7 HOH 161 661 105 HOH HOH A . 
J 7 HOH 162 662 146 HOH HOH A . 
J 7 HOH 163 663 295 HOH HOH A . 
J 7 HOH 164 664 203 HOH HOH A . 
J 7 HOH 165 665 11  HOH HOH A . 
J 7 HOH 166 666 51  HOH HOH A . 
J 7 HOH 167 667 52  HOH HOH A . 
J 7 HOH 168 668 325 HOH HOH A . 
J 7 HOH 169 669 31  HOH HOH A . 
J 7 HOH 170 670 193 HOH HOH A . 
J 7 HOH 171 671 184 HOH HOH A . 
J 7 HOH 172 672 328 HOH HOH A . 
J 7 HOH 173 673 253 HOH HOH A . 
J 7 HOH 174 674 136 HOH HOH A . 
J 7 HOH 175 675 53  HOH HOH A . 
J 7 HOH 176 676 294 HOH HOH A . 
J 7 HOH 177 677 232 HOH HOH A . 
J 7 HOH 178 678 165 HOH HOH A . 
J 7 HOH 179 679 110 HOH HOH A . 
J 7 HOH 180 680 180 HOH HOH A . 
J 7 HOH 181 681 226 HOH HOH A . 
J 7 HOH 182 682 48  HOH HOH A . 
J 7 HOH 183 683 144 HOH HOH A . 
J 7 HOH 184 684 205 HOH HOH A . 
J 7 HOH 185 685 22  HOH HOH A . 
J 7 HOH 186 686 167 HOH HOH A . 
J 7 HOH 187 687 225 HOH HOH A . 
J 7 HOH 188 688 160 HOH HOH A . 
J 7 HOH 189 689 329 HOH HOH A . 
J 7 HOH 190 690 301 HOH HOH A . 
J 7 HOH 191 691 282 HOH HOH A . 
J 7 HOH 192 692 84  HOH HOH A . 
J 7 HOH 193 693 63  HOH HOH A . 
J 7 HOH 194 694 116 HOH HOH A . 
J 7 HOH 195 695 284 HOH HOH A . 
J 7 HOH 196 696 135 HOH HOH A . 
J 7 HOH 197 697 303 HOH HOH A . 
J 7 HOH 198 698 307 HOH HOH A . 
J 7 HOH 199 699 338 HOH HOH A . 
J 7 HOH 200 700 112 HOH HOH A . 
J 7 HOH 201 701 214 HOH HOH A . 
J 7 HOH 202 702 246 HOH HOH A . 
J 7 HOH 203 703 256 HOH HOH A . 
J 7 HOH 204 704 83  HOH HOH A . 
J 7 HOH 205 705 107 HOH HOH A . 
J 7 HOH 206 706 32  HOH HOH A . 
J 7 HOH 207 707 274 HOH HOH A . 
J 7 HOH 208 708 216 HOH HOH A . 
J 7 HOH 209 709 266 HOH HOH A . 
J 7 HOH 210 710 50  HOH HOH A . 
J 7 HOH 211 711 139 HOH HOH A . 
J 7 HOH 212 712 94  HOH HOH A . 
J 7 HOH 213 713 127 HOH HOH A . 
J 7 HOH 214 714 335 HOH HOH A . 
J 7 HOH 215 715 260 HOH HOH A . 
J 7 HOH 216 716 291 HOH HOH A . 
J 7 HOH 217 717 312 HOH HOH A . 
J 7 HOH 218 718 317 HOH HOH A . 
J 7 HOH 219 719 74  HOH HOH A . 
J 7 HOH 220 720 120 HOH HOH A . 
J 7 HOH 221 721 35  HOH HOH A . 
J 7 HOH 222 722 143 HOH HOH A . 
J 7 HOH 223 723 235 HOH HOH A . 
J 7 HOH 224 724 211 HOH HOH A . 
J 7 HOH 225 725 40  HOH HOH A . 
J 7 HOH 226 726 223 HOH HOH A . 
J 7 HOH 227 727 132 HOH HOH A . 
J 7 HOH 228 728 340 HOH HOH A . 
J 7 HOH 229 729 119 HOH HOH A . 
J 7 HOH 230 730 125 HOH HOH A . 
J 7 HOH 231 731 20  HOH HOH A . 
J 7 HOH 232 732 314 HOH HOH A . 
J 7 HOH 233 733 275 HOH HOH A . 
J 7 HOH 234 734 179 HOH HOH A . 
J 7 HOH 235 735 313 HOH HOH A . 
J 7 HOH 236 736 161 HOH HOH A . 
J 7 HOH 237 737 251 HOH HOH A . 
J 7 HOH 238 738 277 HOH HOH A . 
J 7 HOH 239 739 293 HOH HOH A . 
J 7 HOH 240 740 332 HOH HOH A . 
J 7 HOH 241 741 115 HOH HOH A . 
J 7 HOH 242 742 98  HOH HOH A . 
J 7 HOH 243 743 156 HOH HOH A . 
J 7 HOH 244 744 1   HOH HOH A . 
J 7 HOH 245 745 60  HOH HOH A . 
J 7 HOH 246 746 204 HOH HOH A . 
J 7 HOH 247 747 220 HOH HOH A . 
J 7 HOH 248 748 323 HOH HOH A . 
J 7 HOH 249 749 198 HOH HOH A . 
J 7 HOH 250 750 154 HOH HOH A . 
J 7 HOH 251 751 292 HOH HOH A . 
J 7 HOH 252 752 169 HOH HOH A . 
J 7 HOH 253 753 272 HOH HOH A . 
J 7 HOH 254 754 276 HOH HOH A . 
J 7 HOH 255 755 299 HOH HOH A . 
J 7 HOH 256 756 263 HOH HOH A . 
J 7 HOH 257 757 255 HOH HOH A . 
J 7 HOH 258 758 199 HOH HOH A . 
J 7 HOH 259 759 279 HOH HOH A . 
J 7 HOH 260 760 269 HOH HOH A . 
J 7 HOH 261 761 210 HOH HOH A . 
J 7 HOH 262 762 157 HOH HOH A . 
J 7 HOH 263 763 185 HOH HOH A . 
J 7 HOH 264 764 290 HOH HOH A . 
J 7 HOH 265 765 131 HOH HOH A . 
J 7 HOH 266 766 331 HOH HOH A . 
J 7 HOH 267 767 326 HOH HOH A . 
J 7 HOH 268 768 219 HOH HOH A . 
J 7 HOH 269 769 201 HOH HOH A . 
J 7 HOH 270 770 209 HOH HOH A . 
J 7 HOH 271 771 324 HOH HOH A . 
J 7 HOH 272 772 62  HOH HOH A . 
J 7 HOH 273 773 42  HOH HOH A . 
J 7 HOH 274 774 236 HOH HOH A . 
J 7 HOH 275 775 192 HOH HOH A . 
J 7 HOH 276 776 173 HOH HOH A . 
J 7 HOH 277 777 38  HOH HOH A . 
J 7 HOH 278 778 298 HOH HOH A . 
J 7 HOH 279 779 267 HOH HOH A . 
J 7 HOH 280 780 100 HOH HOH A . 
J 7 HOH 281 781 228 HOH HOH A . 
J 7 HOH 282 782 212 HOH HOH A . 
J 7 HOH 283 783 183 HOH HOH A . 
J 7 HOH 284 784 190 HOH HOH A . 
J 7 HOH 285 785 311 HOH HOH A . 
J 7 HOH 286 786 224 HOH HOH A . 
J 7 HOH 287 787 221 HOH HOH A . 
J 7 HOH 288 788 189 HOH HOH A . 
J 7 HOH 289 789 69  HOH HOH A . 
J 7 HOH 290 790 58  HOH HOH A . 
J 7 HOH 291 791 250 HOH HOH A . 
J 7 HOH 292 792 316 HOH HOH A . 
J 7 HOH 293 793 208 HOH HOH A . 
J 7 HOH 294 794 258 HOH HOH A . 
J 7 HOH 295 795 247 HOH HOH A . 
J 7 HOH 296 796 321 HOH HOH A . 
J 7 HOH 297 797 229 HOH HOH A . 
J 7 HOH 298 798 289 HOH HOH A . 
J 7 HOH 299 799 117 HOH HOH A . 
J 7 HOH 300 800 166 HOH HOH A . 
J 7 HOH 301 801 257 HOH HOH A . 
J 7 HOH 302 802 118 HOH HOH A . 
J 7 HOH 303 803 153 HOH HOH A . 
J 7 HOH 304 804 318 HOH HOH A . 
J 7 HOH 305 805 285 HOH HOH A . 
J 7 HOH 306 806 213 HOH HOH A . 
J 7 HOH 307 807 195 HOH HOH A . 
J 7 HOH 308 808 44  HOH HOH A . 
J 7 HOH 309 809 302 HOH HOH A . 
J 7 HOH 310 810 304 HOH HOH A . 
J 7 HOH 311 811 297 HOH HOH A . 
J 7 HOH 312 812 172 HOH HOH A . 
J 7 HOH 313 813 174 HOH HOH A . 
J 7 HOH 314 814 281 HOH HOH A . 
J 7 HOH 315 815 145 HOH HOH A . 
J 7 HOH 316 816 339 HOH HOH A . 
J 7 HOH 317 817 171 HOH HOH A . 
J 7 HOH 318 818 163 HOH HOH A . 
J 7 HOH 319 819 230 HOH HOH A . 
J 7 HOH 320 820 196 HOH HOH A . 
J 7 HOH 321 821 207 HOH HOH A . 
J 7 HOH 322 822 334 HOH HOH A . 
J 7 HOH 323 823 168 HOH HOH A . 
J 7 HOH 324 824 109 HOH HOH A . 
J 7 HOH 325 825 41  HOH HOH A . 
J 7 HOH 326 826 327 HOH HOH A . 
J 7 HOH 327 827 337 HOH HOH A . 
J 7 HOH 328 828 227 HOH HOH A . 
J 7 HOH 329 829 188 HOH HOH A . 
J 7 HOH 330 830 268 HOH HOH A . 
J 7 HOH 331 831 271 HOH HOH A . 
J 7 HOH 332 832 75  HOH HOH A . 
J 7 HOH 333 833 310 HOH HOH A . 
J 7 HOH 334 834 106 HOH HOH A . 
J 7 HOH 335 835 191 HOH HOH A . 
J 7 HOH 336 836 137 HOH HOH A . 
J 7 HOH 337 837 134 HOH HOH A . 
J 7 HOH 338 838 278 HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 4   ? CG  ? A ARG 4   CG  
2  1 Y 1 A ARG 4   ? CD  ? A ARG 4   CD  
3  1 Y 1 A ARG 4   ? NE  ? A ARG 4   NE  
4  1 Y 1 A ARG 4   ? CZ  ? A ARG 4   CZ  
5  1 Y 1 A ARG 4   ? NH1 ? A ARG 4   NH1 
6  1 Y 1 A ARG 4   ? NH2 ? A ARG 4   NH2 
7  1 Y 1 A LYS 191 ? CG  ? A LYS 191 CG  
8  1 Y 1 A LYS 191 ? CD  ? A LYS 191 CD  
9  1 Y 1 A LYS 191 ? CE  ? A LYS 191 CE  
10 1 Y 1 A LYS 191 ? NZ  ? A LYS 191 NZ  
11 1 Y 1 A LYS 255 ? CG  ? A LYS 255 CG  
12 1 Y 1 A LYS 255 ? CD  ? A LYS 255 CD  
13 1 Y 1 A LYS 255 ? CE  ? A LYS 255 CE  
14 1 Y 1 A LYS 255 ? NZ  ? A LYS 255 NZ  
15 1 Y 1 A LYS 316 ? CG  ? A LYS 316 CG  
16 1 Y 1 A LYS 316 ? CD  ? A LYS 316 CD  
17 1 Y 1 A LYS 316 ? CE  ? A LYS 316 CE  
18 1 Y 1 A LYS 316 ? NZ  ? A LYS 316 NZ  
19 1 Y 1 A PRO 317 ? CG  ? A PRO 317 CG  
20 1 Y 1 A PRO 317 ? CD  ? A PRO 317 CD  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.20_4459 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .         2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .         3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .         4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9F7P 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     81.076 
_cell.length_a_esd                 ? 
_cell.length_b                     81.076 
_cell.length_b_esd                 ? 
_cell.length_c                     135.173 
_cell.length_c_esd                 ? 
_cell.volume                       769493.955 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9F7P 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9F7P 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.57 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          65.57 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '1.8 M sodium malonate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            288 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-07-13 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979264 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ALBA BEAMLINE XALOC' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979264 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   XALOC 
_diffrn_source.pdbx_synchrotron_site       ALBA 
# 
_reflns.B_iso_Wilson_estimate                          31.15 
_reflns.entry_id                                       9F7P 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.70 
_reflns.d_resolution_low                               19.69 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     53912 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           94.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                11.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          27.5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.041 
_reflns.pdbx_Rpim_I_all                                0.017 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.000 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.038 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.70 
_reflns_shell.d_res_low                                     1.73 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3052 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               10.1 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.448 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.907 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.929 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               37.46 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9F7P 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.70 
_refine.ls_d_res_low                             19.69 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     53825 
_refine.ls_number_reflns_R_free                  2679 
_refine.ls_number_reflns_R_work                  51146 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    94.08 
_refine.ls_percent_reflns_R_free                 4.98 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1658 
_refine.ls_R_factor_R_free                       0.1795 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1651 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.14 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 21.3330 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1746 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.70 
_refine_hist.d_res_low                        19.69 
_refine_hist.number_atoms_solvent             338 
_refine_hist.number_atoms_total               2843 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2479 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         26 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0083  ? 2565 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0562  ? 3482 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0548  ? 387  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0084  ? 446  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 15.6031 ? 922  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.70 1.73  . . 139 2883 99.60  . . . . 0.2525 . . . . . . . . . . . 0.3329 
'X-RAY DIFFRACTION' 1.73 1.76  . . 167 2763 99.93  . . . . 0.2286 . . . . . . . . . . . 0.2691 
'X-RAY DIFFRACTION' 1.76 1.80  . . 149 2827 99.87  . . . . 0.2227 . . . . . . . . . . . 0.2234 
'X-RAY DIFFRACTION' 1.80 1.84  . . 127 2842 99.87  . . . . 0.1974 . . . . . . . . . . . 0.2176 
'X-RAY DIFFRACTION' 1.84 1.88  . . 155 2824 99.83  . . . . 0.2004 . . . . . . . . . . . 0.2229 
'X-RAY DIFFRACTION' 1.88 1.93  . . 95  1845 65.54  . . . . 0.1920 . . . . . . . . . . . 0.2426 
'X-RAY DIFFRACTION' 1.93 1.98  . . 155 2804 99.90  . . . . 0.1752 . . . . . . . . . . . 0.1985 
'X-RAY DIFFRACTION' 1.98 2.04  . . 117 2864 99.87  . . . . 0.1728 . . . . . . . . . . . 0.1830 
'X-RAY DIFFRACTION' 2.04 2.10  . . 84  1573 55.49  . . . . 0.1805 . . . . . . . . . . . 0.1826 
'X-RAY DIFFRACTION' 2.11 2.18  . . 141 2837 99.93  . . . . 0.1689 . . . . . . . . . . . 0.1945 
'X-RAY DIFFRACTION' 2.18 2.27  . . 78  1929 66.79  . . . . 0.1683 . . . . . . . . . . . 0.1814 
'X-RAY DIFFRACTION' 2.27 2.37  . . 170 2834 100.00 . . . . 0.1723 . . . . . . . . . . . 0.2319 
'X-RAY DIFFRACTION' 2.37 2.50  . . 150 2857 100.00 . . . . 0.1759 . . . . . . . . . . . 0.1825 
'X-RAY DIFFRACTION' 2.50 2.65  . . 145 2852 100.00 . . . . 0.1882 . . . . . . . . . . . 0.2256 
'X-RAY DIFFRACTION' 2.65 2.85  . . 194 2827 100.00 . . . . 0.1874 . . . . . . . . . . . 0.2023 
'X-RAY DIFFRACTION' 2.86 3.14  . . 162 2887 100.00 . . . . 0.1895 . . . . . . . . . . . 0.2023 
'X-RAY DIFFRACTION' 3.14 3.59  . . 139 2900 100.00 . . . . 0.1531 . . . . . . . . . . . 0.1651 
'X-RAY DIFFRACTION' 3.59 4.52  . . 159 2939 100.00 . . . . 0.1300 . . . . . . . . . . . 0.1418 
'X-RAY DIFFRACTION' 4.52 19.69 . . 153 3059 99.94  . . . . 0.1541 . . . . . . . . . . . 0.1454 
# 
_struct.entry_id                     9F7P 
_struct.title                        'SARS-CoV-2 papain-like protease (PLpro) C112S mutant' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9F7P 
_struct_keywords.text            'Protease, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 3 ? 
F N N 5 ? 
G N N 5 ? 
H N N 6 ? 
I N N 6 ? 
J N N 7 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    R1AB_SARS2 
_struct_ref.pdbx_db_accession          P0DTD1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFL
GRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVG
ELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESP
FVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVT
;
_struct_ref.pdbx_align_begin           1564 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9F7P 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 2 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 319 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P0DTD1 
_struct_ref_seq.db_align_beg                  1564 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1881 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       2 
_struct_ref_seq.pdbx_auth_seq_align_end       319 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9F7P MET A 1   ? UNP P0DTD1 ?   ?    'initiating methionine' 1   1 
1 9F7P SER A 112 ? UNP P0DTD1 CYS 1674 'engineered mutation'   112 2 
1 9F7P HIS A 320 ? UNP P0DTD1 ?   ?    'expression tag'        320 3 
1 9F7P HIS A 321 ? UNP P0DTD1 ?   ?    'expression tag'        321 4 
1 9F7P HIS A 322 ? UNP P0DTD1 ?   ?    'expression tag'        322 5 
1 9F7P HIS A 323 ? UNP P0DTD1 ?   ?    'expression tag'        323 6 
1 9F7P HIS A 324 ? UNP P0DTD1 ?   ?    'expression tag'        324 7 
1 9F7P HIS A 325 ? UNP P0DTD1 ?   ?    'expression tag'        325 8 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1380  ? 
1 MORE         -31   ? 
1 'SSA (A^2)'  14820 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'light scattering' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 27  ? GLY A 33  ? THR A 27  GLY A 33  1 ? 7  
HELX_P HELX_P2  AA2 HIS A 48  ? GLU A 52  ? HIS A 48  GLU A 52  5 ? 5  
HELX_P HELX_P3  AA3 ASP A 62  ? HIS A 74  ? ASP A 62  HIS A 74  1 ? 13 
HELX_P HELX_P4  AA4 SER A 79  ? LYS A 92  ? SER A 79  LYS A 92  1 ? 14 
HELX_P HELX_P5  AA5 ASN A 111 ? GLN A 122 ? ASN A 111 GLN A 122 1 ? 12 
HELX_P HELX_P6  AA6 PRO A 130 ? GLY A 143 ? PRO A 130 GLY A 143 1 ? 14 
HELX_P HELX_P7  AA7 ALA A 145 ? ASN A 157 ? ALA A 145 ASN A 157 1 ? 13 
HELX_P HELX_P8  AA8 ASP A 165 ? HIS A 176 ? ASP A 165 HIS A 176 1 ? 12 
HELX_P HELX_P9  AA9 GLY A 202 ? VAL A 206 ? GLY A 202 VAL A 206 1 ? 5  
HELX_P HELX_P10 AB1 SER A 213 ? GLY A 220 ? SER A 213 GLY A 220 1 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A LEU 121 O  ? ? ? 1_555 F NA  . NA ? ? A LEU 121 A NA  405 1_555 ? ? ? ? ? ? ? 2.464 ? ? 
metalc2  metalc ? ? A ILE 124 O  ? ? ? 1_555 F NA  . NA ? ? A ILE 124 A NA  405 1_555 ? ? ? ? ? ? ? 2.290 ? ? 
metalc3  metalc ? ? A ALA 177 O  ? ? ? 1_555 G NA  . NA ? ? A ALA 177 A NA  406 1_555 ? ? ? ? ? ? ? 2.534 ? ? 
metalc4  metalc ? ? A CYS 190 SG ? ? ? 1_555 B ZN  . ZN ? ? A CYS 190 A ZN  401 1_555 ? ? ? ? ? ? ? 2.303 ? ? 
metalc5  metalc ? ? A CYS 193 SG ? ? ? 1_555 B ZN  . ZN ? ? A CYS 193 A ZN  401 1_555 ? ? ? ? ? ? ? 2.369 ? ? 
metalc6  metalc ? ? A CYS 225 SG ? ? ? 1_555 B ZN  . ZN ? ? A CYS 225 A ZN  401 1_555 ? ? ? ? ? ? ? 2.327 ? ? 
metalc7  metalc ? ? A CYS 227 SG ? ? ? 1_555 B ZN  . ZN ? ? A CYS 227 A ZN  401 1_555 ? ? ? ? ? ? ? 2.348 ? ? 
metalc8  metalc ? ? F NA  .   NA ? ? ? 1_555 J HOH . O  ? ? A NA  405 A HOH 583 1_555 ? ? ? ? ? ? ? 2.472 ? ? 
metalc9  metalc ? ? F NA  .   NA ? ? ? 1_555 J HOH . O  ? ? A NA  405 A HOH 701 1_555 ? ? ? ? ? ? ? 2.097 ? ? 
metalc10 metalc ? ? F NA  .   NA ? ? ? 1_555 J HOH . O  ? ? A NA  405 A HOH 742 1_555 ? ? ? ? ? ? ? 2.541 ? ? 
metalc11 metalc ? ? F NA  .   NA ? ? ? 1_555 J HOH . O  ? ? A NA  405 A HOH 749 1_555 ? ? ? ? ? ? ? 2.605 ? ? 
metalc12 metalc ? ? G NA  .   NA ? ? ? 1_555 J HOH . O  ? ? A NA  406 A HOH 504 6_554 ? ? ? ? ? ? ? 2.558 ? ? 
metalc13 metalc ? ? G NA  .   NA ? ? ? 1_555 J HOH . O  ? ? A NA  406 A HOH 547 1_555 ? ? ? ? ? ? ? 2.534 ? ? 
metalc14 metalc ? ? G NA  .   NA ? ? ? 1_555 J HOH . O  ? ? A NA  406 A HOH 567 1_555 ? ? ? ? ? ? ? 2.321 ? ? 
metalc15 metalc ? ? G NA  .   NA ? ? ? 1_555 J HOH . O  ? ? A NA  406 A HOH 666 1_555 ? ? ? ? ? ? ? 2.348 ? ? 
metalc16 metalc ? ? G NA  .   NA ? ? ? 1_555 J HOH . O  ? ? A NA  406 A HOH 708 1_555 ? ? ? ? ? ? ? 2.496 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O  ? A LEU 121 ? A LEU 121 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? A ILE 124 ? A ILE 124 ? 1_555 84.8  ? 
2  O  ? A LEU 121 ? A LEU 121 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 583 ? 1_555 100.7 ? 
3  O  ? A ILE 124 ? A ILE 124 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 583 ? 1_555 162.0 ? 
4  O  ? A LEU 121 ? A LEU 121 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 701 ? 1_555 85.9  ? 
5  O  ? A ILE 124 ? A ILE 124 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 701 ? 1_555 101.7 ? 
6  O  ? J HOH .   ? A HOH 583 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 701 ? 1_555 95.8  ? 
7  O  ? A LEU 121 ? A LEU 121 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 742 ? 1_555 97.0  ? 
8  O  ? A ILE 124 ? A ILE 124 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 742 ? 1_555 84.2  ? 
9  O  ? J HOH .   ? A HOH 583 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 742 ? 1_555 78.2  ? 
10 O  ? J HOH .   ? A HOH 701 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 742 ? 1_555 173.6 ? 
11 O  ? A LEU 121 ? A LEU 121 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 749 ? 1_555 165.2 ? 
12 O  ? A ILE 124 ? A ILE 124 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 749 ? 1_555 87.9  ? 
13 O  ? J HOH .   ? A HOH 583 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 749 ? 1_555 90.1  ? 
14 O  ? J HOH .   ? A HOH 701 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 749 ? 1_555 82.9  ? 
15 O  ? J HOH .   ? A HOH 742 ? 1_555 NA ? F NA . ? A NA 405 ? 1_555 O  ? J HOH .   ? A HOH 749 ? 1_555 95.0  ? 
16 O  ? A ALA 177 ? A ALA 177 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 504 ? 6_554 174.0 ? 
17 O  ? A ALA 177 ? A ALA 177 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 547 ? 1_555 88.8  ? 
18 O  ? J HOH .   ? A HOH 504 ? 6_554 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 547 ? 1_555 92.0  ? 
19 O  ? A ALA 177 ? A ALA 177 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 567 ? 1_555 92.4  ? 
20 O  ? J HOH .   ? A HOH 504 ? 6_554 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 567 ? 1_555 87.8  ? 
21 O  ? J HOH .   ? A HOH 547 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 567 ? 1_555 170.8 ? 
22 O  ? A ALA 177 ? A ALA 177 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 666 ? 1_555 86.0  ? 
23 O  ? J HOH .   ? A HOH 504 ? 6_554 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 666 ? 1_555 88.3  ? 
24 O  ? J HOH .   ? A HOH 547 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 666 ? 1_555 81.6  ? 
25 O  ? J HOH .   ? A HOH 567 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 666 ? 1_555 107.5 ? 
26 O  ? A ALA 177 ? A ALA 177 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 708 ? 1_555 88.7  ? 
27 O  ? J HOH .   ? A HOH 504 ? 6_554 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 708 ? 1_555 97.2  ? 
28 O  ? J HOH .   ? A HOH 547 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 708 ? 1_555 79.2  ? 
29 O  ? J HOH .   ? A HOH 567 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 708 ? 1_555 91.7  ? 
30 O  ? J HOH .   ? A HOH 666 ? 1_555 NA ? G NA . ? A NA 406 ? 1_555 O  ? J HOH .   ? A HOH 708 ? 1_555 160.2 ? 
31 SG ? A CYS 190 ? A CYS 190 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 193 ? A CYS 193 ? 1_555 111.2 ? 
32 SG ? A CYS 190 ? A CYS 190 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 225 ? A CYS 225 ? 1_555 117.0 ? 
33 SG ? A CYS 193 ? A CYS 193 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 225 ? A CYS 225 ? 1_555 104.1 ? 
34 SG ? A CYS 190 ? A CYS 190 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 227 ? A CYS 227 ? 1_555 104.9 ? 
35 SG ? A CYS 193 ? A CYS 193 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 227 ? A CYS 227 ? 1_555 112.0 ? 
36 SG ? A CYS 225 ? A CYS 225 ? 1_555 ZN ? B ZN . ? A ZN 401 ? 1_555 SG ? A CYS 227 ? A CYS 227 ? 1_555 107.8 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 HIS A 18  ? ASP A 23  ? HIS A 18  ASP A 23  
AA1 2 THR A 5   ? THR A 11  ? THR A 5   THR A 11  
AA1 3 THR A 55  ? VAL A 58  ? THR A 55  VAL A 58  
AA1 4 THR A 35  ? LEU A 37  ? THR A 35  LEU A 37  
AA1 5 ALA A 40  ? ASP A 41  ? ALA A 40  ASP A 41  
AA2 1 GLN A 98  ? VAL A 99  ? GLN A 98  VAL A 99  
AA2 2 LEU A 102 ? THR A 103 ? LEU A 102 THR A 103 
AA3 1 GLY A 194 ? LYS A 201 ? GLY A 194 LYS A 201 
AA3 2 LYS A 183 ? CYS A 190 ? LYS A 183 CYS A 190 
AA3 3 GLN A 230 ? GLU A 239 ? GLN A 230 GLU A 239 
AA3 4 VAL A 221 ? PRO A 224 ? VAL A 221 PRO A 224 
AA4 1 GLY A 194 ? LYS A 201 ? GLY A 194 LYS A 201 
AA4 2 LYS A 183 ? CYS A 190 ? LYS A 183 CYS A 190 
AA4 3 GLN A 230 ? GLU A 239 ? GLN A 230 GLU A 239 
AA4 4 SER A 310 ? THR A 312 ? SER A 310 THR A 312 
AA5 1 MET A 207 ? MET A 209 ? MET A 207 MET A 209 
AA5 2 PHE A 242 ? LEU A 254 ? PHE A 242 LEU A 254 
AA5 3 TYR A 297 ? LYS A 307 ? TYR A 297 LYS A 307 
AA5 4 CYS A 261 ? ASN A 268 ? CYS A 261 ASN A 268 
AA5 5 CYS A 271 ? SER A 279 ? CYS A 271 SER A 279 
AA5 6 LEU A 283 ? ASP A 287 ? LEU A 283 ASP A 287 
AA5 7 LEU A 290 ? SER A 294 ? LEU A 290 SER A 294 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLN A 20  ? O GLN A 20  N VAL A 8   ? N VAL A 8   
AA1 2 3 N PHE A 9   ? N PHE A 9   O PHE A 56  ? O PHE A 56  
AA1 3 4 O TYR A 57  ? O TYR A 57  N TYR A 36  ? N TYR A 36  
AA1 4 5 N LEU A 37  ? N LEU A 37  O ALA A 40  ? O ALA A 40  
AA2 1 2 N VAL A 99  ? N VAL A 99  O LEU A 102 ? O LEU A 102 
AA3 1 2 O LEU A 200 ? O LEU A 200 N ARG A 184 ? N ARG A 184 
AA3 2 3 N VAL A 189 ? N VAL A 189 O THR A 232 ? O THR A 232 
AA3 3 4 O ALA A 231 ? O ALA A 231 N ILE A 223 ? N ILE A 223 
AA4 1 2 O LEU A 200 ? O LEU A 200 N ARG A 184 ? N ARG A 184 
AA4 2 3 N VAL A 189 ? N VAL A 189 O THR A 232 ? O THR A 232 
AA4 3 4 N GLN A 238 ? N GLN A 238 O TYR A 311 ? O TYR A 311 
AA5 1 2 N TYR A 208 ? N TYR A 208 O SER A 246 ? O SER A 246 
AA5 2 3 N MET A 245 ? N MET A 245 O VAL A 304 ? O VAL A 304 
AA5 3 4 O PHE A 305 ? O PHE A 305 N CYS A 261 ? N CYS A 261 
AA5 4 5 N GLU A 264 ? N GLU A 264 O LYS A 275 ? O LYS A 275 
AA5 5 6 N HIS A 276 ? N HIS A 276 O ILE A 286 ? O ILE A 286 
AA5 6 7 N CYS A 285 ? N CYS A 285 O THR A 292 ? O THR A 292 
# 
_pdbx_entry_details.entry_id                   9F7P 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ILE A 15  ? ? -123.48 -59.83  
2 1 SER A 104 ? ? -107.80 -169.21 
3 1 CYS A 271 ? ? -157.46 52.72   
4 1 LYS A 280 ? ? -122.32 -129.85 
5 1 ASN A 309 ? A -135.53 -73.35  
6 1 ASN A 309 ? B -148.78 -66.43  
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    A 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     819 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   J 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       838 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.15 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A GLU 2   ? A GLU 2   
3  1 Y 1 A VAL 318 ? A VAL 318 
4  1 Y 1 A THR 319 ? A THR 319 
5  1 Y 1 A HIS 320 ? A HIS 320 
6  1 Y 1 A HIS 321 ? A HIS 321 
7  1 Y 1 A HIS 322 ? A HIS 322 
8  1 Y 1 A HIS 323 ? A HIS 323 
9  1 Y 1 A HIS 324 ? A HIS 324 
10 1 Y 1 A HIS 325 ? A HIS 325 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
HOH O    O  N N 159 
HOH H1   H  N N 160 
HOH H2   H  N N 161 
ILE N    N  N N 162 
ILE CA   C  N S 163 
ILE C    C  N N 164 
ILE O    O  N N 165 
ILE CB   C  N S 166 
ILE CG1  C  N N 167 
ILE CG2  C  N N 168 
ILE CD1  C  N N 169 
ILE OXT  O  N N 170 
ILE H    H  N N 171 
ILE H2   H  N N 172 
ILE HA   H  N N 173 
ILE HB   H  N N 174 
ILE HG12 H  N N 175 
ILE HG13 H  N N 176 
ILE HG21 H  N N 177 
ILE HG22 H  N N 178 
ILE HG23 H  N N 179 
ILE HD11 H  N N 180 
ILE HD12 H  N N 181 
ILE HD13 H  N N 182 
ILE HXT  H  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
MLI C1   C  N N 251 
MLI C2   C  N N 252 
MLI C3   C  N N 253 
MLI O6   O  N N 254 
MLI O7   O  N N 255 
MLI O8   O  N N 256 
MLI O9   O  N N 257 
MLI H11  H  N N 258 
MLI H12  H  N N 259 
NA  NA   NA N N 260 
PEG C1   C  N N 261 
PEG O1   O  N N 262 
PEG C2   C  N N 263 
PEG O2   O  N N 264 
PEG C3   C  N N 265 
PEG C4   C  N N 266 
PEG O4   O  N N 267 
PEG H11  H  N N 268 
PEG H12  H  N N 269 
PEG HO1  H  N N 270 
PEG H21  H  N N 271 
PEG H22  H  N N 272 
PEG H31  H  N N 273 
PEG H32  H  N N 274 
PEG H41  H  N N 275 
PEG H42  H  N N 276 
PEG HO4  H  N N 277 
PHE N    N  N N 278 
PHE CA   C  N S 279 
PHE C    C  N N 280 
PHE O    O  N N 281 
PHE CB   C  N N 282 
PHE CG   C  Y N 283 
PHE CD1  C  Y N 284 
PHE CD2  C  Y N 285 
PHE CE1  C  Y N 286 
PHE CE2  C  Y N 287 
PHE CZ   C  Y N 288 
PHE OXT  O  N N 289 
PHE H    H  N N 290 
PHE H2   H  N N 291 
PHE HA   H  N N 292 
PHE HB2  H  N N 293 
PHE HB3  H  N N 294 
PHE HD1  H  N N 295 
PHE HD2  H  N N 296 
PHE HE1  H  N N 297 
PHE HE2  H  N N 298 
PHE HZ   H  N N 299 
PHE HXT  H  N N 300 
PRO N    N  N N 301 
PRO CA   C  N S 302 
PRO C    C  N N 303 
PRO O    O  N N 304 
PRO CB   C  N N 305 
PRO CG   C  N N 306 
PRO CD   C  N N 307 
PRO OXT  O  N N 308 
PRO H    H  N N 309 
PRO HA   H  N N 310 
PRO HB2  H  N N 311 
PRO HB3  H  N N 312 
PRO HG2  H  N N 313 
PRO HG3  H  N N 314 
PRO HD2  H  N N 315 
PRO HD3  H  N N 316 
PRO HXT  H  N N 317 
SER N    N  N N 318 
SER CA   C  N S 319 
SER C    C  N N 320 
SER O    O  N N 321 
SER CB   C  N N 322 
SER OG   O  N N 323 
SER OXT  O  N N 324 
SER H    H  N N 325 
SER H2   H  N N 326 
SER HA   H  N N 327 
SER HB2  H  N N 328 
SER HB3  H  N N 329 
SER HG   H  N N 330 
SER HXT  H  N N 331 
THR N    N  N N 332 
THR CA   C  N S 333 
THR C    C  N N 334 
THR O    O  N N 335 
THR CB   C  N R 336 
THR OG1  O  N N 337 
THR CG2  C  N N 338 
THR OXT  O  N N 339 
THR H    H  N N 340 
THR H2   H  N N 341 
THR HA   H  N N 342 
THR HB   H  N N 343 
THR HG1  H  N N 344 
THR HG21 H  N N 345 
THR HG22 H  N N 346 
THR HG23 H  N N 347 
THR HXT  H  N N 348 
TRP N    N  N N 349 
TRP CA   C  N S 350 
TRP C    C  N N 351 
TRP O    O  N N 352 
TRP CB   C  N N 353 
TRP CG   C  Y N 354 
TRP CD1  C  Y N 355 
TRP CD2  C  Y N 356 
TRP NE1  N  Y N 357 
TRP CE2  C  Y N 358 
TRP CE3  C  Y N 359 
TRP CZ2  C  Y N 360 
TRP CZ3  C  Y N 361 
TRP CH2  C  Y N 362 
TRP OXT  O  N N 363 
TRP H    H  N N 364 
TRP H2   H  N N 365 
TRP HA   H  N N 366 
TRP HB2  H  N N 367 
TRP HB3  H  N N 368 
TRP HD1  H  N N 369 
TRP HE1  H  N N 370 
TRP HE3  H  N N 371 
TRP HZ2  H  N N 372 
TRP HZ3  H  N N 373 
TRP HH2  H  N N 374 
TRP HXT  H  N N 375 
TYR N    N  N N 376 
TYR CA   C  N S 377 
TYR C    C  N N 378 
TYR O    O  N N 379 
TYR CB   C  N N 380 
TYR CG   C  Y N 381 
TYR CD1  C  Y N 382 
TYR CD2  C  Y N 383 
TYR CE1  C  Y N 384 
TYR CE2  C  Y N 385 
TYR CZ   C  Y N 386 
TYR OH   O  N N 387 
TYR OXT  O  N N 388 
TYR H    H  N N 389 
TYR H2   H  N N 390 
TYR HA   H  N N 391 
TYR HB2  H  N N 392 
TYR HB3  H  N N 393 
TYR HD1  H  N N 394 
TYR HD2  H  N N 395 
TYR HE1  H  N N 396 
TYR HE2  H  N N 397 
TYR HH   H  N N 398 
TYR HXT  H  N N 399 
VAL N    N  N N 400 
VAL CA   C  N S 401 
VAL C    C  N N 402 
VAL O    O  N N 403 
VAL CB   C  N N 404 
VAL CG1  C  N N 405 
VAL CG2  C  N N 406 
VAL OXT  O  N N 407 
VAL H    H  N N 408 
VAL H2   H  N N 409 
VAL HA   H  N N 410 
VAL HB   H  N N 411 
VAL HG11 H  N N 412 
VAL HG12 H  N N 413 
VAL HG13 H  N N 414 
VAL HG21 H  N N 415 
VAL HG22 H  N N 416 
VAL HG23 H  N N 417 
VAL HXT  H  N N 418 
ZN  ZN   ZN N N 419 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
MLI C1  C2   sing N N 237 
MLI C1  C3   sing N N 238 
MLI C1  H11  sing N N 239 
MLI C1  H12  sing N N 240 
MLI C2  O6   doub N N 241 
MLI C2  O7   sing N N 242 
MLI C3  O8   doub N N 243 
MLI C3  O9   sing N N 244 
PEG C1  O1   sing N N 245 
PEG C1  C2   sing N N 246 
PEG C1  H11  sing N N 247 
PEG C1  H12  sing N N 248 
PEG O1  HO1  sing N N 249 
PEG C2  O2   sing N N 250 
PEG C2  H21  sing N N 251 
PEG C2  H22  sing N N 252 
PEG O2  C3   sing N N 253 
PEG C3  C4   sing N N 254 
PEG C3  H31  sing N N 255 
PEG C3  H32  sing N N 256 
PEG C4  O4   sing N N 257 
PEG C4  H41  sing N N 258 
PEG C4  H42  sing N N 259 
PEG O4  HO4  sing N N 260 
PHE N   CA   sing N N 261 
PHE N   H    sing N N 262 
PHE N   H2   sing N N 263 
PHE CA  C    sing N N 264 
PHE CA  CB   sing N N 265 
PHE CA  HA   sing N N 266 
PHE C   O    doub N N 267 
PHE C   OXT  sing N N 268 
PHE CB  CG   sing N N 269 
PHE CB  HB2  sing N N 270 
PHE CB  HB3  sing N N 271 
PHE CG  CD1  doub Y N 272 
PHE CG  CD2  sing Y N 273 
PHE CD1 CE1  sing Y N 274 
PHE CD1 HD1  sing N N 275 
PHE CD2 CE2  doub Y N 276 
PHE CD2 HD2  sing N N 277 
PHE CE1 CZ   doub Y N 278 
PHE CE1 HE1  sing N N 279 
PHE CE2 CZ   sing Y N 280 
PHE CE2 HE2  sing N N 281 
PHE CZ  HZ   sing N N 282 
PHE OXT HXT  sing N N 283 
PRO N   CA   sing N N 284 
PRO N   CD   sing N N 285 
PRO N   H    sing N N 286 
PRO CA  C    sing N N 287 
PRO CA  CB   sing N N 288 
PRO CA  HA   sing N N 289 
PRO C   O    doub N N 290 
PRO C   OXT  sing N N 291 
PRO CB  CG   sing N N 292 
PRO CB  HB2  sing N N 293 
PRO CB  HB3  sing N N 294 
PRO CG  CD   sing N N 295 
PRO CG  HG2  sing N N 296 
PRO CG  HG3  sing N N 297 
PRO CD  HD2  sing N N 298 
PRO CD  HD3  sing N N 299 
PRO OXT HXT  sing N N 300 
SER N   CA   sing N N 301 
SER N   H    sing N N 302 
SER N   H2   sing N N 303 
SER CA  C    sing N N 304 
SER CA  CB   sing N N 305 
SER CA  HA   sing N N 306 
SER C   O    doub N N 307 
SER C   OXT  sing N N 308 
SER CB  OG   sing N N 309 
SER CB  HB2  sing N N 310 
SER CB  HB3  sing N N 311 
SER OG  HG   sing N N 312 
SER OXT HXT  sing N N 313 
THR N   CA   sing N N 314 
THR N   H    sing N N 315 
THR N   H2   sing N N 316 
THR CA  C    sing N N 317 
THR CA  CB   sing N N 318 
THR CA  HA   sing N N 319 
THR C   O    doub N N 320 
THR C   OXT  sing N N 321 
THR CB  OG1  sing N N 322 
THR CB  CG2  sing N N 323 
THR CB  HB   sing N N 324 
THR OG1 HG1  sing N N 325 
THR CG2 HG21 sing N N 326 
THR CG2 HG22 sing N N 327 
THR CG2 HG23 sing N N 328 
THR OXT HXT  sing N N 329 
TRP N   CA   sing N N 330 
TRP N   H    sing N N 331 
TRP N   H2   sing N N 332 
TRP CA  C    sing N N 333 
TRP CA  CB   sing N N 334 
TRP CA  HA   sing N N 335 
TRP C   O    doub N N 336 
TRP C   OXT  sing N N 337 
TRP CB  CG   sing N N 338 
TRP CB  HB2  sing N N 339 
TRP CB  HB3  sing N N 340 
TRP CG  CD1  doub Y N 341 
TRP CG  CD2  sing Y N 342 
TRP CD1 NE1  sing Y N 343 
TRP CD1 HD1  sing N N 344 
TRP CD2 CE2  doub Y N 345 
TRP CD2 CE3  sing Y N 346 
TRP NE1 CE2  sing Y N 347 
TRP NE1 HE1  sing N N 348 
TRP CE2 CZ2  sing Y N 349 
TRP CE3 CZ3  doub Y N 350 
TRP CE3 HE3  sing N N 351 
TRP CZ2 CH2  doub Y N 352 
TRP CZ2 HZ2  sing N N 353 
TRP CZ3 CH2  sing Y N 354 
TRP CZ3 HZ3  sing N N 355 
TRP CH2 HH2  sing N N 356 
TRP OXT HXT  sing N N 357 
TYR N   CA   sing N N 358 
TYR N   H    sing N N 359 
TYR N   H2   sing N N 360 
TYR CA  C    sing N N 361 
TYR CA  CB   sing N N 362 
TYR CA  HA   sing N N 363 
TYR C   O    doub N N 364 
TYR C   OXT  sing N N 365 
TYR CB  CG   sing N N 366 
TYR CB  HB2  sing N N 367 
TYR CB  HB3  sing N N 368 
TYR CG  CD1  doub Y N 369 
TYR CG  CD2  sing Y N 370 
TYR CD1 CE1  sing Y N 371 
TYR CD1 HD1  sing N N 372 
TYR CD2 CE2  doub Y N 373 
TYR CD2 HD2  sing N N 374 
TYR CE1 CZ   doub Y N 375 
TYR CE1 HE1  sing N N 376 
TYR CE2 CZ   sing Y N 377 
TYR CE2 HE2  sing N N 378 
TYR CZ  OH   sing N N 379 
TYR OH  HH   sing N N 380 
TYR OXT HXT  sing N N 381 
VAL N   CA   sing N N 382 
VAL N   H    sing N N 383 
VAL N   H2   sing N N 384 
VAL CA  C    sing N N 385 
VAL CA  CB   sing N N 386 
VAL CA  HA   sing N N 387 
VAL C   O    doub N N 388 
VAL C   OXT  sing N N 389 
VAL CB  CG1  sing N N 390 
VAL CB  CG2  sing N N 391 
VAL CB  HB   sing N N 392 
VAL CG1 HG11 sing N N 393 
VAL CG1 HG12 sing N N 394 
VAL CG1 HG13 sing N N 395 
VAL CG2 HG21 sing N N 396 
VAL CG2 HG22 sing N N 397 
VAL CG2 HG23 sing N N 398 
VAL OXT HXT  sing N N 399 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                Spain 
_pdbx_audit_support.grant_number           P20_00149 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7d6h 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9F7P 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012334 
_atom_sites.fract_transf_matrix[1][2]   0.007121 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.014242 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007398 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CL ? ? 9.50761  7.44341 ? ? 1.04373  23.83732 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345  0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
NA ? ? 9.38062  1.54875 ? ? 3.38349  72.32734 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 24.64596 5.25405 ? ? 2.14387  29.76375 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . VAL A 1 3   ? 53.35000  -41.74300 7.38700   1.000 51.98781  ? 3   VAL A N    1 
ATOM   2    C  CA   . VAL A 1 3   ? 52.29000  -41.34800 6.45200   1.000 76.11176  ? 3   VAL A CA   1 
ATOM   3    C  C    . VAL A 1 3   ? 52.71500  -40.18800 5.55400   1.000 69.51623  ? 3   VAL A C    1 
ATOM   4    O  O    . VAL A 1 3   ? 52.99400  -39.08700 6.03800   1.000 69.00301  ? 3   VAL A O    1 
ATOM   5    C  CB   . VAL A 1 3   ? 50.98700  -40.96000 7.19300   1.000 72.14549  ? 3   VAL A CB   1 
ATOM   6    C  CG1  . VAL A 1 3   ? 49.82200  -40.83800 6.20500   1.000 65.90790  ? 3   VAL A CG1  1 
ATOM   7    C  CG2  . VAL A 1 3   ? 50.67900  -41.96000 8.30300   1.000 76.85658  ? 3   VAL A CG2  1 
ATOM   8    H  HA   . VAL A 1 3   ? 52.12200  -42.12100 5.89000   1.000 91.34000  ? 3   VAL A HA   1 
ATOM   9    H  HB   . VAL A 1 3   ? 51.10700  -40.09300 7.61100   1.000 86.57000  ? 3   VAL A HB   1 
ATOM   10   H  HG11 . VAL A 1 3   ? 48.99100  -40.78400 6.70200   1.000 79.09000  ? 3   VAL A HG11 1 
ATOM   11   H  HG12 . VAL A 1 3   ? 49.94200  -40.03500 5.67400   1.000 79.09000  ? 3   VAL A HG12 1 
ATOM   12   H  HG13 . VAL A 1 3   ? 49.81400  -41.61800 5.62900   1.000 79.09000  ? 3   VAL A HG13 1 
ATOM   13   H  HG21 . VAL A 1 3   ? 49.80400  -41.76200 8.67200   1.000 92.23000  ? 3   VAL A HG21 1 
ATOM   14   H  HG22 . VAL A 1 3   ? 50.68600  -42.85600 7.93100   1.000 92.23000  ? 3   VAL A HG22 1 
ATOM   15   H  HG23 . VAL A 1 3   ? 51.35500  -41.88300 8.99400   1.000 92.23000  ? 3   VAL A HG23 1 
ATOM   16   N  N    . ARG A 1 4   ? 52.73500  -40.42700 4.24500   1.000 59.80980  ? 4   ARG A N    1 
ATOM   17   C  CA   . ARG A 1 4   ? 53.22500  -39.45800 3.27400   1.000 50.87452  ? 4   ARG A CA   1 
ATOM   18   C  C    . ARG A 1 4   ? 52.04100  -38.76600 2.60800   1.000 47.37147  ? 4   ARG A C    1 
ATOM   19   O  O    . ARG A 1 4   ? 51.06300  -39.42400 2.23900   1.000 47.24251  ? 4   ARG A O    1 
ATOM   20   C  CB   . ARG A 1 4   ? 54.11100  -40.15100 2.23400   1.000 48.45581  ? 4   ARG A CB   1 
ATOM   21   H  H    . ARG A 1 4   ? 52.46400  -41.16200 3.89000   1.000 71.77000  ? 4   ARG A H    1 
ATOM   22   H  HA   . ARG A 1 4   ? 53.75400  -38.77700 3.71600   1.000 61.05000  ? 4   ARG A HA   1 
ATOM   23   N  N    . THR A 1 5   ? 52.12500  -37.44300 2.48000   1.000 46.50558  ? 5   THR A N    1 
ATOM   24   C  CA   . THR A 1 5   ? 51.04800  -36.65400 1.89600   1.000 43.02358  ? 5   THR A CA   1 
ATOM   25   C  C    . THR A 1 5   ? 51.59500  -35.61000 0.93200   1.000 42.79987  ? 5   THR A C    1 
ATOM   26   O  O    . THR A 1 5   ? 52.75200  -35.18800 1.02900   1.000 43.72893  ? 5   THR A O    1 
ATOM   27   C  CB   . THR A 1 5   ? 50.22700  -35.92800 2.97900   1.000 47.07933  ? 5   THR A CB   1 
ATOM   28   O  OG1  . THR A 1 5   ? 51.04400  -34.91500 3.59500   1.000 48.18999  ? 5   THR A OG1  1 
ATOM   29   C  CG2  . THR A 1 5   ? 49.72600  -36.88800 4.03900   1.000 45.80812  ? 5   THR A CG2  1 
ATOM   30   H  H    . THR A 1 5   ? 52.80400  -36.97600 2.72700   1.000 55.81000  ? 5   THR A H    1 
ATOM   31   H  HA   . THR A 1 5   ? 50.48000  -37.26100 1.39600   1.000 51.63000  ? 5   THR A HA   1 
ATOM   32   H  HB   . THR A 1 5   ? 49.44900  -35.52200 2.56600   1.000 56.49000  ? 5   THR A HB   1 
ATOM   33   H  HG1  . THR A 1 5   ? 50.60500  -34.51200 4.18700   1.000 57.83000  ? 5   THR A HG1  1 
ATOM   34   H  HG21 . THR A 1 5   ? 49.15400  -36.41900 4.66700   1.000 54.97000  ? 5   THR A HG21 1 
ATOM   35   H  HG22 . THR A 1 5   ? 49.21800  -37.60400 3.62600   1.000 54.97000  ? 5   THR A HG22 1 
ATOM   36   H  HG23 . THR A 1 5   ? 50.47600  -37.27100 4.52100   1.000 54.97000  ? 5   THR A HG23 1 
ATOM   37   N  N    . ILE A 1 6   ? 50.72900  -35.18600 -0.00100  1.000 42.28139  ? 6   ILE A N    1 
ATOM   38   C  CA   . ILE A 1 6   ? 50.93500  -33.97100 -0.77300  1.000 40.24956  ? 6   ILE A CA   1 
ATOM   39   C  C    . ILE A 1 6   ? 49.67800  -33.11400 -0.67700  1.000 41.85239  ? 6   ILE A C    1 
ATOM   40   O  O    . ILE A 1 6   ? 48.57900  -33.59700 -0.38000  1.000 37.71505  ? 6   ILE A O    1 
ATOM   41   C  CB   . ILE A 1 6   ? 51.26100  -34.22400 -2.26400  1.000 42.82092  ? 6   ILE A CB   1 
ATOM   42   C  CG1  . ILE A 1 6   ? 50.15700  -35.05100 -2.91900  1.000 40.87332  ? 6   ILE A CG1  1 
ATOM   43   C  CG2  . ILE A 1 6   ? 52.60800  -34.89200 -2.41100  1.000 46.50031  ? 6   ILE A CG2  1 
ATOM   44   C  CD1  . ILE A 1 6   ? 50.22300  -35.07200 -4.43300  1.000 43.06832  ? 6   ILE A CD1  1 
ATOM   45   H  H    . ILE A 1 6   ? 50.00200  -35.59900 -0.20100  1.000 50.74000  ? 6   ILE A H    1 
ATOM   46   H  HA   . ILE A 1 6   ? 51.68600  -33.49700 -0.38200  1.000 48.30000  ? 6   ILE A HA   1 
ATOM   47   H  HB   . ILE A 1 6   ? 51.30300  -33.36800 -2.71800  1.000 51.38000  ? 6   ILE A HB   1 
ATOM   48   H  HG12 . ILE A 1 6   ? 50.22600  -35.96700 -2.60700  1.000 49.05000  ? 6   ILE A HG12 1 
ATOM   49   H  HG13 . ILE A 1 6   ? 49.29700  -34.67900 -2.66600  1.000 49.05000  ? 6   ILE A HG13 1 
ATOM   50   H  HG21 . ILE A 1 6   ? 52.82400  -34.96300 -3.35400  1.000 55.80000  ? 6   ILE A HG21 1 
ATOM   51   H  HG22 . ILE A 1 6   ? 53.27800  -34.35700 -1.95800  1.000 55.80000  ? 6   ILE A HG22 1 
ATOM   52   H  HG23 . ILE A 1 6   ? 52.56800  -35.77600 -2.01400  1.000 55.80000  ? 6   ILE A HG23 1 
ATOM   53   H  HD11 . ILE A 1 6   ? 49.43400  -35.51700 -4.77800  1.000 51.68000  ? 6   ILE A HD11 1 
ATOM   54   H  HD12 . ILE A 1 6   ? 50.25800  -34.15900 -4.76000  1.000 51.68000  ? 6   ILE A HD12 1 
ATOM   55   H  HD13 . ILE A 1 6   ? 51.02000  -35.55200 -4.70700  1.000 51.68000  ? 6   ILE A HD13 1 
ATOM   56   N  N    . LYS A 1 7   ? 49.85700  -31.82600 -0.94600  1.000 39.69423  ? 7   LYS A N    1 
ATOM   57   C  CA   . LYS A 1 7   ? 48.74600  -30.90100 -1.09200  1.000 36.43595  ? 7   LYS A CA   1 
ATOM   58   C  C    . LYS A 1 7   ? 48.33600  -30.85100 -2.55000  1.000 34.90418  ? 7   LYS A C    1 
ATOM   59   O  O    . LYS A 1 7   ? 49.18600  -30.67200 -3.42700  1.000 37.57819  ? 7   LYS A O    1 
ATOM   60   C  CB   . LYS A 1 7   ? 49.13200  -29.49800 -0.63000  1.000 35.84640  ? 7   LYS A CB   1 
ATOM   61   C  CG   . LYS A 1 7   ? 47.99600  -28.49000 -0.68900  1.000 41.36549  ? 7   LYS A CG   1 
ATOM   62   C  CD   . LYS A 1 7   ? 48.51000  -27.05100 -0.50400  1.000 41.33654  ? 7   LYS A CD   1 
ATOM   63   C  CE   . LYS A 1 7   ? 49.47300  -26.64500 -1.62700  1.000 41.71026  ? 7   LYS A CE   1 
ATOM   64   N  NZ   . LYS A 1 7   ? 50.10500  -25.32100 -1.34700  1.000 42.35771  ? 7   LYS A NZ   1 
ATOM   65   H  H    . LYS A 1 7   ? 50.62800  -31.46000 -1.05100  1.000 47.63000  ? 7   LYS A H    1 
ATOM   66   H  HA   . LYS A 1 7   ? 48.00200  -31.20700 -0.55000  1.000 43.72000  ? 7   LYS A HA   1 
ATOM   67   H  HB2  . LYS A 1 7   ? 49.43500  -29.54700 0.29000   1.000 43.02000  ? 7   LYS A HB2  1 
ATOM   68   H  HB3  . LYS A 1 7   ? 49.84700  -29.17000 -1.19700  1.000 43.02000  ? 7   LYS A HB3  1 
ATOM   69   H  HG2  . LYS A 1 7   ? 47.55800  -28.54900 -1.55300  1.000 49.64000  ? 7   LYS A HG2  1 
ATOM   70   H  HG3  . LYS A 1 7   ? 47.36000  -28.68000 0.01800   1.000 49.64000  ? 7   LYS A HG3  1 
ATOM   71   H  HD2  . LYS A 1 7   ? 47.75800  -26.43800 -0.51100  1.000 49.60000  ? 7   LYS A HD2  1 
ATOM   72   H  HD3  . LYS A 1 7   ? 48.98300  -26.98600 0.34000   1.000 49.60000  ? 7   LYS A HD3  1 
ATOM   73   H  HE2  . LYS A 1 7   ? 50.17500  -27.30900 -1.70500  1.000 50.05000  ? 7   LYS A HE2  1 
ATOM   74   H  HE3  . LYS A 1 7   ? 48.98300  -26.58000 -2.46200  1.000 50.05000  ? 7   LYS A HE3  1 
ATOM   75   H  HZ1  . LYS A 1 7   ? 50.65900  -25.10300 -2.00800  1.000 50.83000  ? 7   LYS A HZ1  1 
ATOM   76   H  HZ2  . LYS A 1 7   ? 49.47800  -24.69300 -1.27700  1.000 50.83000  ? 7   LYS A HZ2  1 
ATOM   77   H  HZ3  . LYS A 1 7   ? 50.56300  -25.35800 -0.58600  1.000 50.83000  ? 7   LYS A HZ3  1 
ATOM   78   N  N    . VAL A 1 8   ? 47.03700  -30.99700 -2.80300  1.000 34.96735  ? 8   VAL A N    1 
ATOM   79   C  CA   . VAL A 1 8   ? 46.45400  -30.76100 -4.11700  1.000 31.74591  ? 8   VAL A CA   1 
ATOM   80   C  C    . VAL A 1 8   ? 45.22300  -29.89000 -3.90800  1.000 32.60391  ? 8   VAL A C    1 
ATOM   81   O  O    . VAL A 1 8   ? 44.80000  -29.62700 -2.78100  1.000 32.38283  ? 8   VAL A O    1 
ATOM   82   C  CB   . VAL A 1 8   ? 46.08400  -32.06600 -4.85900  1.000 33.86195  ? 8   VAL A CB   1 
ATOM   83   C  CG1  . VAL A 1 8   ? 47.30600  -32.96600 -4.98100  1.000 34.88576  ? 8   VAL A CG1  1 
ATOM   84   C  CG2  . VAL A 1 8   ? 44.94200  -32.78700 -4.16500  1.000 36.87284  ? 8   VAL A CG2  1 
ATOM   85   H  H    . VAL A 1 8   ? 46.46100  -31.23900 -2.21300  1.000 41.96000  ? 8   VAL A H    1 
ATOM   86   H  HA   . VAL A 1 8   ? 47.09000  -30.28800 -4.67600  1.000 38.09000  ? 8   VAL A HA   1 
ATOM   87   H  HB   . VAL A 1 8   ? 45.78100  -31.84200 -5.75300  1.000 40.63000  ? 8   VAL A HB   1 
ATOM   88   H  HG11 . VAL A 1 8   ? 47.06600  -33.75700 -5.48700  1.000 41.86000  ? 8   VAL A HG11 1 
ATOM   89   H  HG12 . VAL A 1 8   ? 48.01000  -32.48100 -5.43900  1.000 41.86000  ? 8   VAL A HG12 1 
ATOM   90   H  HG13 . VAL A 1 8   ? 47.60200  -33.21800 -4.09300  1.000 41.86000  ? 8   VAL A HG13 1 
ATOM   91   H  HG21 . VAL A 1 8   ? 44.87900  -33.68900 -4.51400  1.000 44.25000  ? 8   VAL A HG21 1 
ATOM   92   H  HG22 . VAL A 1 8   ? 45.11800  -32.81200 -3.21100  1.000 44.25000  ? 8   VAL A HG22 1 
ATOM   93   H  HG23 . VAL A 1 8   ? 44.11600  -32.30800 -4.33600  1.000 44.25000  ? 8   VAL A HG23 1 
ATOM   94   N  N    . PHE A 1 9   ? 44.64900  -29.43600 -5.01200  1.000 30.86423  ? 9   PHE A N    1 
ATOM   95   C  CA   . PHE A 1 9   ? 43.39500  -28.69900 -4.98700  1.000 32.00647  ? 9   PHE A CA   1 
ATOM   96   C  C    . PHE A 1 9   ? 42.37000  -29.45300 -5.80400  1.000 31.18005  ? 9   PHE A C    1 
ATOM   97   O  O    . PHE A 1 9   ? 42.67000  -29.93100 -6.90000  1.000 33.98302  ? 9   PHE A O    1 
ATOM   98   C  CB   . PHE A 1 9   ? 43.56400  -27.28300 -5.53400  1.000 31.41429  ? 9   PHE A CB   1 
ATOM   99   C  CG   . PHE A 1 9   ? 44.61300  -26.50400 -4.81100  1.000 30.27205  ? 9   PHE A CG   1 
ATOM   100  C  CD1  . PHE A 1 9   ? 44.36200  -25.98900 -3.54800  1.000 30.06413  ? 9   PHE A CD1  1 
ATOM   101  C  CD2  . PHE A 1 9   ? 45.86200  -26.30600 -5.37000  1.000 32.42494  ? 9   PHE A CD2  1 
ATOM   102  C  CE1  . PHE A 1 9   ? 45.32600  -25.30200 -2.88200  1.000 32.38546  ? 9   PHE A CE1  1 
ATOM   103  C  CE2  . PHE A 1 9   ? 46.83000  -25.60700 -4.70500  1.000 35.62532  ? 9   PHE A CE2  1 
ATOM   104  C  CZ   . PHE A 1 9   ? 46.56700  -25.11000 -3.44800  1.000 36.06748  ? 9   PHE A CZ   1 
ATOM   105  H  H    . PHE A 1 9   ? 44.97200  -29.54400 -5.80100  1.000 37.04000  ? 9   PHE A H    1 
ATOM   106  H  HA   . PHE A 1 9   ? 43.07600  -28.62400 -4.07400  1.000 38.41000  ? 9   PHE A HA   1 
ATOM   107  H  HB2  . PHE A 1 9   ? 43.81900  -27.33400 -6.46900  1.000 37.70000  ? 9   PHE A HB2  1 
ATOM   108  H  HB3  . PHE A 1 9   ? 42.72300  -26.80800 -5.44500  1.000 37.70000  ? 9   PHE A HB3  1 
ATOM   109  H  HD1  . PHE A 1 9   ? 43.52800  -26.11500 -3.15500  1.000 36.08000  ? 9   PHE A HD1  1 
ATOM   110  H  HD2  . PHE A 1 9   ? 46.04600  -26.65300 -6.21200  1.000 38.91000  ? 9   PHE A HD2  1 
ATOM   111  H  HE1  . PHE A 1 9   ? 45.14600  -24.95800 -2.03700  1.000 38.86000  ? 9   PHE A HE1  1 
ATOM   112  H  HE2  . PHE A 1 9   ? 47.66100  -25.46800 -5.09900  1.000 42.75000  ? 9   PHE A HE2  1 
ATOM   113  H  HZ   . PHE A 1 9   ? 47.22600  -24.64700 -2.98200  1.000 43.28000  ? 9   PHE A HZ   1 
ATOM   114  N  N    . THR A 1 10  ? 41.16800  -29.57500 -5.25700  1.000 30.15625  ? 10  THR A N    1 
ATOM   115  C  CA   . THR A 1 10  ? 40.02800  -30.07100 -6.01100  1.000 29.90359  ? 10  THR A CA   1 
ATOM   116  C  C    . THR A 1 10  ? 39.11500  -28.92000 -6.40100  1.000 28.96400  ? 10  THR A C    1 
ATOM   117  O  O    . THR A 1 10  ? 39.15100  -27.82600 -5.82300  1.000 27.96125  ? 10  THR A O    1 
ATOM   118  C  CB   . THR A 1 10  ? 39.22800  -31.12800 -5.23800  1.000 31.54326  ? 10  THR A CB   1 
ATOM   119  O  OG1  . THR A 1 10  ? 38.82900  -30.57600 -3.97500  1.000 31.26691  ? 10  THR A OG1  1 
ATOM   120  C  CG2  . THR A 1 10  ? 40.03700  -32.39400 -5.06500  1.000 32.79077  ? 10  THR A CG2  1 
ATOM   121  H  H    . THR A 1 10  ? 40.98700  -29.37300 -4.44000  1.000 36.19000  ? 10  THR A H    1 
ATOM   122  H  HA   . THR A 1 10  ? 40.36100  -30.50000 -6.81500  1.000 35.89000  ? 10  THR A HA   1 
ATOM   123  H  HB   . THR A 1 10  ? 38.43000  -31.37900 -5.72800  1.000 37.85000  ? 10  THR A HB   1 
ATOM   124  H  HG1  . THR A 1 10  ? 38.38800  -31.14400 -3.54000  1.000 37.52000  ? 10  THR A HG1  1 
ATOM   125  H  HG21 . THR A 1 10  ? 39.51000  -33.06400 -4.60300  1.000 39.35000  ? 10  THR A HG21 1 
ATOM   126  H  HG22 . THR A 1 10  ? 40.29900  -32.74100 -5.93200  1.000 39.35000  ? 10  THR A HG22 1 
ATOM   127  H  HG23 . THR A 1 10  ? 40.83600  -32.20900 -4.54600  1.000 39.35000  ? 10  THR A HG23 1 
ATOM   128  N  N    . THR A 1 11  ? 38.32700  -29.17300 -7.43800  1.000 29.77989  ? 11  THR A N    1 
ATOM   129  C  CA   . THR A 1 11  ? 37.47600  -28.15500 -8.02200  1.000 29.13244  ? 11  THR A CA   1 
ATOM   130  C  C    . THR A 1 11  ? 36.36300  -28.83300 -8.79900  1.000 26.71899  ? 11  THR A C    1 
ATOM   131  O  O    . THR A 1 11  ? 36.46400  -29.99700 -9.18100  1.000 26.69004  ? 11  THR A O    1 
ATOM   132  C  CB   . THR A 1 11  ? 38.28300  -27.24400 -8.95500  1.000 28.65870  ? 11  THR A CB   1 
ATOM   133  O  OG1  . THR A 1 11  ? 37.52800  -26.07100 -9.27200  1.000 28.73239  ? 11  THR A OG1  1 
ATOM   134  C  CG2  . THR A 1 11  ? 38.64000  -28.01000 -10.21600 1.000 29.14823  ? 11  THR A CG2  1 
ATOM   135  H  H    . THR A 1 11  ? 38.26800  -29.93800 -7.82500  1.000 35.74000  ? 11  THR A H    1 
ATOM   136  H  HA   . THR A 1 11  ? 37.07800  -27.62200 -7.31700  1.000 34.96000  ? 11  THR A HA   1 
ATOM   137  H  HB   . THR A 1 11  ? 39.10400  -26.95900 -8.52400  1.000 34.39000  ? 11  THR A HB   1 
ATOM   138  H  HG1  . THR A 1 11  ? 37.35700  -25.64200 -8.57000  1.000 34.48000  ? 11  THR A HG1  1 
ATOM   139  H  HG21 . THR A 1 11  ? 39.39800  -27.59300 -10.65400 1.000 34.98000  ? 11  THR A HG21 1 
ATOM   140  H  HG22 . THR A 1 11  ? 38.86900  -28.92600 -9.99400  1.000 34.98000  ? 11  THR A HG22 1 
ATOM   141  H  HG23 . THR A 1 11  ? 37.88600  -28.01300 -10.82600 1.000 34.98000  ? 11  THR A HG23 1 
ATOM   142  N  N    . VAL A 1 12  ? 35.29000  -28.08500 -9.01700  1.000 28.61133  ? 12  VAL A N    1 
ATOM   143  C  CA   . VAL A 1 12  ? 34.30600  -28.44000 -10.03000 1.000 28.67186  ? 12  VAL A CA   1 
ATOM   144  C  C    . VAL A 1 12  ? 34.22700  -27.42000 -11.15400 1.000 28.73766  ? 12  VAL A C    1 
ATOM   145  O  O    . VAL A 1 12  ? 33.64600  -27.73300 -12.20200 1.000 28.78240  ? 12  VAL A O    1 
ATOM   146  C  CB   . VAL A 1 12  ? 32.90100  -28.67500 -9.42800  1.000 29.25351  ? 12  VAL A CB   1 
ATOM   147  C  CG1  . VAL A 1 12  ? 32.90500  -29.91000 -8.51600  1.000 29.72198  ? 12  VAL A CG1  1 
ATOM   148  C  CG2  . VAL A 1 12  ? 32.38200  -27.44000 -8.69100  1.000 29.53249  ? 12  VAL A CG2  1 
ATOM   149  H  H    . VAL A 1 12  ? 35.10700  -27.36200 -8.58800  1.000 34.34000  ? 12  VAL A H    1 
ATOM   150  H  HA   . VAL A 1 12  ? 34.58300  -29.28300 -10.42200 1.000 34.41000  ? 12  VAL A HA   1 
ATOM   151  H  HB   . VAL A 1 12  ? 32.28500  -28.84200 -10.15800 1.000 35.10000  ? 12  VAL A HB   1 
ATOM   152  H  HG11 . VAL A 1 12  ? 32.01600  -30.03500 -8.14900  1.000 35.67000  ? 12  VAL A HG11 1 
ATOM   153  H  HG12 . VAL A 1 12  ? 33.15900  -30.68700 -9.03800  1.000 35.67000  ? 12  VAL A HG12 1 
ATOM   154  H  HG13 . VAL A 1 12  ? 33.54200  -29.77100 -7.79800  1.000 35.67000  ? 12  VAL A HG13 1 
ATOM   155  H  HG21 . VAL A 1 12  ? 31.51100  -27.63900 -8.31600  1.000 35.44000  ? 12  VAL A HG21 1 
ATOM   156  H  HG22 . VAL A 1 12  ? 33.00300  -27.21100 -7.98200  1.000 35.44000  ? 12  VAL A HG22 1 
ATOM   157  H  HG23 . VAL A 1 12  ? 32.31200  -26.70400 -9.31900  1.000 35.44000  ? 12  VAL A HG23 1 
ATOM   158  N  N    . ASP A 1 13  ? 34.80000  -26.22800 -10.99200 1.000 29.67724  ? 13  ASP A N    1 
ATOM   159  C  CA   . ASP A 1 13  ? 34.71000  -25.17900 -12.00700 1.000 31.48272  ? 13  ASP A CA   1 
ATOM   160  C  C    . ASP A 1 13  ? 36.05600  -24.61800 -12.45300 1.000 32.94869  ? 13  ASP A C    1 
ATOM   161  O  O    . ASP A 1 13  ? 36.08000  -23.74600 -13.33900 1.000 31.69854  ? 13  ASP A O    1 
ATOM   162  C  CB   . ASP A 1 13  ? 33.78300  -24.05000 -11.51100 1.000 30.57998  ? 13  ASP A CB   1 
ATOM   163  C  CG   . ASP A 1 13  ? 34.28200  -23.35800 -10.26200 1.000 32.21176  ? 13  ASP A CG   1 
ATOM   164  O  OD1  . ASP A 1 13  ? 35.48000  -23.46300 -9.93600  1.000 31.84592  ? 13  ASP A OD1  1 
ATOM   165  O  OD2  . ASP A 1 13  ? 33.45300  -22.68700 -9.59200  1.000 32.53548  ? 13  ASP A OD2  1 
ATOM   166  H  H    . ASP A 1 13  ? 35.25000  -25.99900 -10.29600 1.000 35.61000  ? 13  ASP A H    1 
ATOM   167  H  HA   . ASP A 1 13  ? 34.30800  -25.55200 -12.80700 1.000 37.78000  ? 13  ASP A HA   1 
ATOM   168  H  HB2  . ASP A 1 13  ? 33.70400  -23.38100 -12.20900 1.000 36.70000  ? 13  ASP A HB2  1 
ATOM   169  H  HB3  . ASP A 1 13  ? 32.91100  -24.42700 -11.31300 1.000 36.70000  ? 13  ASP A HB3  1 
ATOM   170  N  N    . ASN A 1 14  ? 37.17100  -25.12900 -11.91500 1.000 30.17993  ? 14  ASN A N    1 
ATOM   171  C  CA   . ASN A 1 14  ? 38.53000  -24.69300 -12.23900 1.000 31.99068  ? 14  ASN A CA   1 
ATOM   172  C  C    . ASN A 1 14  ? 38.79700  -23.24600 -11.84300 1.000 32.25387  ? 14  ASN A C    1 
ATOM   173  O  O    . ASN A 1 14  ? 39.77000  -22.63300 -12.31100 1.000 32.00910  ? 14  ASN A O    1 
ATOM   174  C  CB   . ASN A 1 14  ? 38.85100  -24.88200 -13.72900 1.000 35.04104  ? 14  ASN A CB   1 
ATOM   175  C  CG   . ASN A 1 14  ? 40.32400  -25.20200 -13.97400 1.000 37.59924  ? 14  ASN A CG   1 
ATOM   176  O  OD1  . ASN A 1 14  ? 41.01800  -25.75700 -13.11400 1.000 36.06485  ? 14  ASN A OD1  1 
ATOM   177  N  ND2  . ASN A 1 14  ? 40.80800  -24.83800 -15.14200 1.000 42.97094  ? 14  ASN A ND2  1 
ATOM   178  H  H    . ASN A 1 14  ? 37.16200  -25.76200 -11.33300 1.000 36.21000  ? 14  ASN A H    1 
ATOM   179  H  HA   . ASN A 1 14  ? 39.13500  -25.25200 -11.72600 1.000 38.39000  ? 14  ASN A HA   1 
ATOM   180  H  HB2  . ASN A 1 14  ? 38.32200  -25.61600 -14.07700 1.000 42.05000  ? 14  ASN A HB2  1 
ATOM   181  H  HB3  . ASN A 1 14  ? 38.63800  -24.06400 -14.20600 1.000 42.05000  ? 14  ASN A HB3  1 
ATOM   182  H  HD21 . ASN A 1 14  ? 41.63100  -24.99400 -15.33400 1.000 51.56000  ? 14  ASN A HD21 1 
ATOM   183  H  HD22 . ASN A 1 14  ? 40.30000  -24.44500 -15.71400 1.000 51.56000  ? 14  ASN A HD22 1 
ATOM   184  N  N    . ILE A 1 15  ? 37.97200  -22.70100 -10.95900 1.000 31.72486  ? 15  ILE A N    1 
ATOM   185  C  CA   . ILE A 1 15  ? 38.12200  -21.33300 -10.49200 1.000 29.33246  ? 15  ILE A CA   1 
ATOM   186  C  C    . ILE A 1 15  ? 38.23700  -21.37700 -8.97800  1.000 32.48021  ? 15  ILE A C    1 
ATOM   187  O  O    . ILE A 1 15  ? 39.23100  -20.94100 -8.39500  1.000 33.07502  ? 15  ILE A O    1 
ATOM   188  C  CB   . ILE A 1 15  ? 36.93800  -20.45600 -10.92100 1.000 32.87499  ? 15  ILE A CB   1 
ATOM   189  C  CG1  . ILE A 1 15  ? 36.93900  -20.27800 -12.43900 1.000 32.10648  ? 15  ILE A CG1  1 
ATOM   190  C  CG2  . ILE A 1 15  ? 37.00000  -19.11300 -10.23000 1.000 35.28055  ? 15  ILE A CG2  1 
ATOM   191  C  CD1  . ILE A 1 15  ? 35.61500  -19.80200 -12.97900 1.000 35.58585  ? 15  ILE A CD1  1 
ATOM   192  H  H    . ILE A 1 15  ? 37.30300  -23.11200 -10.60700 1.000 38.07000  ? 15  ILE A H    1 
ATOM   193  H  HA   . ILE A 1 15  ? 38.92600  -20.94400 -10.87200 1.000 35.20000  ? 15  ILE A HA   1 
ATOM   194  H  HB   . ILE A 1 15  ? 36.11500  -20.89900 -10.66000 1.000 39.45000  ? 15  ILE A HB   1 
ATOM   195  H  HG12 . ILE A 1 15  ? 37.61200  -19.62200 -12.67800 1.000 38.53000  ? 15  ILE A HG12 1 
ATOM   196  H  HG13 . ILE A 1 15  ? 37.14300  -21.13000 -12.85500 1.000 38.53000  ? 15  ILE A HG13 1 
ATOM   197  H  HG21 . ILE A 1 15  ? 36.42300  -18.49000 -10.69900 1.000 42.34000  ? 15  ILE A HG21 1 
ATOM   198  H  HG22 . ILE A 1 15  ? 36.70000  -19.21500 -9.31300  1.000 42.34000  ? 15  ILE A HG22 1 
ATOM   199  H  HG23 . ILE A 1 15  ? 37.91500  -18.79200 -10.24500 1.000 42.34000  ? 15  ILE A HG23 1 
ATOM   200  H  HD11 . ILE A 1 15  ? 35.63300  -19.85200 -13.94800 1.000 42.71000  ? 15  ILE A HD11 1 
ATOM   201  H  HD12 . ILE A 1 15  ? 34.90900  -20.37000 -12.63200 1.000 42.71000  ? 15  ILE A HD12 1 
ATOM   202  H  HD13 . ILE A 1 15  ? 35.46900  -18.88500 -12.69800 1.000 42.71000  ? 15  ILE A HD13 1 
ATOM   203  N  N    . ASN A 1 16  ? 37.20900  -21.90400 -8.34200  1.000 33.19872  ? 16  ASN A N    1 
ATOM   204  C  CA   . ASN A 1 16  ? 37.17300  -22.04200 -6.89600  1.000 31.89067  ? 16  ASN A CA   1 
ATOM   205  C  C    . ASN A 1 16  ? 37.85900  -23.33900 -6.51500  1.000 29.94570  ? 16  ASN A C    1 
ATOM   206  O  O    . ASN A 1 16  ? 37.45200  -24.41700 -6.94600  1.000 29.15350  ? 16  ASN A O    1 
ATOM   207  C  CB   . ASN A 1 16  ? 35.72300  -21.95300 -6.44900  1.000 36.12012  ? 16  ASN A CB   1 
ATOM   208  C  CG   . ASN A 1 16  ? 35.06400  -20.65300 -6.93400  1.000 45.89761  ? 16  ASN A CG   1 
ATOM   209  O  OD1  . ASN A 1 16  ? 35.39200  -19.57000 -6.45000  1.000 43.83683  ? 16  ASN A OD1  1 
ATOM   210  N  ND2  . ASN A 1 16  ? 34.22200  -20.75000 -7.96300  1.000 40.01532  ? 16  ASN A ND2  1 
ATOM   211  H  H    . ASN A 1 16  ? 36.50200  -22.19700 -8.73300  1.000 39.84000  ? 16  ASN A H    1 
ATOM   212  H  HA   . ASN A 1 16  ? 37.66300  -21.34100 -6.43900  1.000 38.27000  ? 16  ASN A HA   1 
ATOM   213  H  HB2  . ASN A 1 16  ? 35.22800  -22.70200 -6.81500  1.000 43.34000  ? 16  ASN A HB2  1 
ATOM   214  H  HB3  . ASN A 1 16  ? 35.68400  -21.97200 -5.48000  1.000 43.34000  ? 16  ASN A HB3  1 
ATOM   215  H  HD21 . ASN A 1 16  ? 34.06900  -21.51600 -8.32300  1.000 48.02000  ? 16  ASN A HD21 1 
ATOM   216  H  HD22 . ASN A 1 16  ? 33.83100  -20.04700 -8.26600  1.000 48.02000  ? 16  ASN A HD22 1 
ATOM   217  N  N    . LEU A 1 17  ? 38.90900  -23.22100 -5.70700  1.000 31.19321  ? 17  LEU A N    1 
ATOM   218  C  CA   . LEU A 1 17  ? 39.77600  -24.33100 -5.36100  1.000 25.37936  ? 17  LEU A CA   1 
ATOM   219  C  C    . LEU A 1 17  ? 39.51000  -24.76500 -3.93100  1.000 28.74555  ? 17  LEU A C    1 
ATOM   220  O  O    . LEU A 1 17  ? 39.13400  -23.95500 -3.07400  1.000 31.62484  ? 17  LEU A O    1 
ATOM   221  C  CB   . LEU A 1 17  ? 41.24800  -23.95100 -5.51700  1.000 29.71409  ? 17  LEU A CB   1 
ATOM   222  C  CG   . LEU A 1 17  ? 41.59500  -23.41900 -6.91100  1.000 30.75632  ? 17  LEU A CG   1 
ATOM   223  C  CD1  . LEU A 1 17  ? 43.08700  -23.17800 -7.04200  1.000 34.88576  ? 17  LEU A CD1  1 
ATOM   224  C  CD2  . LEU A 1 17  ? 41.11400  -24.38800 -7.96500  1.000 33.66983  ? 17  LEU A CD2  1 
ATOM   225  H  H    . LEU A 1 17  ? 39.14300  -22.48100 -5.33600  1.000 37.43000  ? 17  LEU A H    1 
ATOM   226  H  HA   . LEU A 1 17  ? 39.59500  -25.08000 -5.95100  1.000 30.46000  ? 17  LEU A HA   1 
ATOM   227  H  HB2  . LEU A 1 17  ? 41.46200  -23.25900 -4.87200  1.000 35.66000  ? 17  LEU A HB2  1 
ATOM   228  H  HB3  . LEU A 1 17  ? 41.79200  -24.73700 -5.35400  1.000 35.66000  ? 17  LEU A HB3  1 
ATOM   229  H  HG   . LEU A 1 17  ? 41.15100  -22.56800 -7.04800  1.000 36.91000  ? 17  LEU A HG   1 
ATOM   230  H  HD11 . LEU A 1 17  ? 43.27500  -22.83400 -7.92900  1.000 41.86000  ? 17  LEU A HD11 1 
ATOM   231  H  HD12 . LEU A 1 17  ? 43.36300  -22.53200 -6.37200  1.000 41.86000  ? 17  LEU A HD12 1 
ATOM   232  H  HD13 . LEU A 1 17  ? 43.55600  -24.01600 -6.90500  1.000 41.86000  ? 17  LEU A HD13 1 
ATOM   233  H  HD21 . LEU A 1 17  ? 41.57300  -24.20100 -8.79900  1.000 40.41000  ? 17  LEU A HD21 1 
ATOM   234  H  HD22 . LEU A 1 17  ? 41.31000  -25.29300 -7.67600  1.000 40.41000  ? 17  LEU A HD22 1 
ATOM   235  H  HD23 . LEU A 1 17  ? 40.15700  -24.27800 -8.08200  1.000 40.41000  ? 17  LEU A HD23 1 
ATOM   236  N  N    . HIS A 1 18  ? 39.74400  -26.04500 -3.67500  1.000 28.46657  ? 18  HIS A N    1 
ATOM   237  C  CA   . HIS A 1 18  ? 39.53000  -26.62000 -2.35000  1.000 31.50115  ? 18  HIS A CA   1 
ATOM   238  C  C    . HIS A 1 18  ? 40.77600  -27.38800 -1.95400  1.000 32.87499  ? 18  HIS A C    1 
ATOM   239  O  O    . HIS A 1 18  ? 41.13200  -28.37500 -2.60600  1.000 29.46932  ? 18  HIS A O    1 
ATOM   240  C  CB   . HIS A 1 18  ? 38.29700  -27.50700 -2.37900  1.000 30.23257  ? 18  HIS A CB   1 
ATOM   241  C  CG   . HIS A 1 18  ? 37.05500  -26.75800 -2.75400  1.000 32.34862  ? 18  HIS A CG   1 
ATOM   242  N  ND1  . HIS A 1 18  ? 36.33100  -26.02200 -1.84200  1.000 34.45676  ? 18  HIS A ND1  1 
ATOM   243  C  CD2  . HIS A 1 18  ? 36.46400  -26.55500 -3.95600  1.000 31.54589  ? 18  HIS A CD2  1 
ATOM   244  C  CE1  . HIS A 1 18  ? 35.31000  -25.44500 -2.45400  1.000 33.43296  ? 18  HIS A CE1  1 
ATOM   245  N  NE2  . HIS A 1 18  ? 35.37000  -25.75200 -3.74100  1.000 30.75106  ? 18  HIS A NE2  1 
ATOM   246  H  H    . HIS A 1 18  ? 40.03100  -26.60900 -4.25800  1.000 34.16000  ? 18  HIS A H    1 
ATOM   247  H  HA   . HIS A 1 18  ? 39.39700  -25.93000 -1.68100  1.000 37.80000  ? 18  HIS A HA   1 
ATOM   248  H  HB2  . HIS A 1 18  ? 38.43100  -28.21300 -3.03200  1.000 36.28000  ? 18  HIS A HB2  1 
ATOM   249  H  HB3  . HIS A 1 18  ? 38.16300  -27.89100 -1.49900  1.000 36.28000  ? 18  HIS A HB3  1 
ATOM   250  H  HD1  . HIS A 1 18  ? 36.51500  -25.94800 -1.00500  1.000 41.35000  ? 18  HIS A HD1  1 
ATOM   251  H  HD2  . HIS A 1 18  ? 36.74600  -26.89500 -4.77400  1.000 37.85000  ? 18  HIS A HD2  1 
ATOM   252  H  HE1  . HIS A 1 18  ? 34.66100  -24.91600 -2.05000  1.000 40.12000  ? 18  HIS A HE1  1 
ATOM   253  H  HE2  . HIS A 1 18  ? 34.81500  -25.49100 -4.34400  1.000 36.90000  ? 18  HIS A HE2  1 
ATOM   254  N  N    . THR A 1 19  ? 41.43600  -26.92300 -0.89900  1.000 30.69579  ? 19  THR A N    1 
ATOM   255  C  CA   . THR A 1 19  ? 42.69400  -27.52000 -0.46600  1.000 33.35137  ? 19  THR A CA   1 
ATOM   256  C  C    . THR A 1 19  ? 42.44400  -28.92800 0.04400   1.000 35.00683  ? 19  THR A C    1 
ATOM   257  O  O    . THR A 1 19  ? 41.52400  -29.15700 0.83500   1.000 33.47243  ? 19  THR A O    1 
ATOM   258  C  CB   . THR A 1 19  ? 43.35400  -26.68400 0.63500   1.000 31.31691  ? 19  THR A CB   1 
ATOM   259  O  OG1  . THR A 1 19  ? 43.36700  -25.29800 0.27400   1.000 31.70907  ? 19  THR A OG1  1 
ATOM   260  C  CG2  . THR A 1 19  ? 44.77900  -27.12700 0.85300   1.000 31.24848  ? 19  THR A CG2  1 
ATOM   261  H  H    . THR A 1 19  ? 41.17700  -26.26200 -0.41400  1.000 36.83000  ? 19  THR A H    1 
ATOM   262  H  HA   . THR A 1 19  ? 43.30300  -27.55300 -1.22000  1.000 40.02000  ? 19  THR A HA   1 
ATOM   263  H  HB   . THR A 1 19  ? 42.84900  -26.80200 1.45500   1.000 37.58000  ? 19  THR A HB   1 
ATOM   264  H  HG1  . THR A 1 19  ? 42.58000  -25.00600 0.22900   1.000 38.05000  ? 19  THR A HG1  1 
ATOM   265  H  HG21 . THR A 1 19  ? 45.20700  -26.55500 1.50900   1.000 37.50000  ? 19  THR A HG21 1 
ATOM   266  H  HG22 . THR A 1 19  ? 44.79600  -28.04200 1.17400   1.000 37.50000  ? 19  THR A HG22 1 
ATOM   267  H  HG23 . THR A 1 19  ? 45.27300  -27.07600 0.02000   1.000 37.50000  ? 19  THR A HG23 1 
ATOM   268  N  N    . GLN A 1 20  ? 43.27100  -29.87000 -0.39700  1.000 30.69842  ? 20  GLN A N    1 
ATOM   269  C  CA   . GLN A 1 20  ? 43.19300  -31.24400 0.07000   1.000 33.90143  ? 20  GLN A CA   1 
ATOM   270  C  C    . GLN A 1 20  ? 44.57700  -31.72200 0.46800   1.000 38.15721  ? 20  GLN A C    1 
ATOM   271  O  O    . GLN A 1 20  ? 45.56400  -31.42400 -0.20500  1.000 39.54685  ? 20  GLN A O    1 
ATOM   272  C  CB   . GLN A 1 20  ? 42.65900  -32.20300 -0.99300  1.000 35.12526  ? 20  GLN A CB   1 
ATOM   273  C  CG   . GLN A 1 20  ? 41.31700  -31.85500 -1.56300  1.000 36.88337  ? 20  GLN A CG   1 
ATOM   274  C  CD   . GLN A 1 20  ? 40.22600  -31.81100 -0.53500  1.000 37.83085  ? 20  GLN A CD   1 
ATOM   275  O  OE1  . GLN A 1 20  ? 40.29700  -32.46400 0.50800   1.000 36.12802  ? 20  GLN A OE1  1 
ATOM   276  N  NE2  . GLN A 1 20  ? 39.19300  -31.04300 -0.82700  1.000 39.73371  ? 20  GLN A NE2  1 
ATOM   277  H  H    . GLN A 1 20  ? 43.89300  -29.73300 -0.97400  1.000 36.84000  ? 20  GLN A H    1 
ATOM   278  H  HA   . GLN A 1 20  ? 42.59600  -31.26400 0.83400   1.000 40.68000  ? 20  GLN A HA   1 
ATOM   279  H  HB2  . GLN A 1 20  ? 43.28900  -32.22200 -1.73100  1.000 42.15000  ? 20  GLN A HB2  1 
ATOM   280  H  HB3  . GLN A 1 20  ? 42.58400  -33.08600 -0.59800  1.000 42.15000  ? 20  GLN A HB3  1 
ATOM   281  H  HG2  . GLN A 1 20  ? 41.37000  -30.98000 -1.97800  1.000 44.26000  ? 20  GLN A HG2  1 
ATOM   282  H  HG3  . GLN A 1 20  ? 41.07400  -32.52200 -2.22400  1.000 44.26000  ? 20  GLN A HG3  1 
ATOM   283  H  HE21 . GLN A 1 20  ? 39.17700  -30.60800 -1.56900  1.000 47.68000  ? 20  GLN A HE21 1 
ATOM   284  H  HE22 . GLN A 1 20  ? 38.53700  -30.97800 -0.27500  1.000 47.68000  ? 20  GLN A HE22 1 
ATOM   285  N  N    . VAL A 1 21  ? 44.65100  -32.47000 1.55400   1.000 35.23844  ? 21  VAL A N    1 
ATOM   286  C  CA   . VAL A 1 21  ? 45.87400  -33.16800 1.92700   1.000 36.55175  ? 21  VAL A CA   1 
ATOM   287  C  C    . VAL A 1 21  ? 45.61100  -34.63900 1.67100   1.000 40.66277  ? 21  VAL A C    1 
ATOM   288  O  O    . VAL A 1 21  ? 44.79100  -35.25500 2.36100   1.000 43.11570  ? 21  VAL A O    1 
ATOM   289  C  CB   . VAL A 1 21  ? 46.26300  -32.90900 3.38800   1.000 45.06593  ? 21  VAL A CB   1 
ATOM   290  C  CG1  . VAL A 1 21  ? 47.52300  -33.69800 3.73600   1.000 46.16869  ? 21  VAL A CG1  1 
ATOM   291  C  CG2  . VAL A 1 21  ? 46.44900  -31.41300 3.61400   1.000 45.16594  ? 21  VAL A CG2  1 
ATOM   292  H  H    . VAL A 1 21  ? 43.99800  -32.59200 2.10000   1.000 42.28000  ? 21  VAL A H    1 
ATOM   293  H  HA   . VAL A 1 21  ? 46.61200  -32.87200 1.37200   1.000 43.86000  ? 21  VAL A HA   1 
ATOM   294  H  HB   . VAL A 1 21  ? 45.55800  -33.20900 3.98200   1.000 54.08000  ? 21  VAL A HB   1 
ATOM   295  H  HG11 . VAL A 1 21  ? 47.86800  -33.38200 4.58600   1.000 55.40000  ? 21  VAL A HG11 1 
ATOM   296  H  HG12 . VAL A 1 21  ? 47.29900  -34.63900 3.79900   1.000 55.40000  ? 21  VAL A HG12 1 
ATOM   297  H  HG13 . VAL A 1 21  ? 48.18400  -33.56100 3.04000   1.000 55.40000  ? 21  VAL A HG13 1 
ATOM   298  H  HG21 . VAL A 1 21  ? 46.78300  -31.26900 4.51300   1.000 54.20000  ? 21  VAL A HG21 1 
ATOM   299  H  HG22 . VAL A 1 21  ? 47.08500  -31.07200 2.96600   1.000 54.20000  ? 21  VAL A HG22 1 
ATOM   300  H  HG23 . VAL A 1 21  ? 45.59400  -30.96900 3.50400   1.000 54.20000  ? 21  VAL A HG23 1 
ATOM   301  N  N    . VAL A 1 22  ? 46.27300  -35.20800 0.67100   1.000 40.68646  ? 22  VAL A N    1 
ATOM   302  C  CA   . VAL A 1 22  ? 45.98700  -36.56700 0.23800   1.000 40.17061  ? 22  VAL A CA   1 
ATOM   303  C  C    . VAL A 1 22  ? 47.09100  -37.50900 0.68200   1.000 43.67629  ? 22  VAL A C    1 
ATOM   304  O  O    . VAL A 1 22  ? 48.27400  -37.15000 0.70600   1.000 43.59207  ? 22  VAL A O    1 
ATOM   305  C  CB   . VAL A 1 22  ? 45.78600  -36.66300 -1.28600  1.000 42.45246  ? 22  VAL A CB   1 
ATOM   306  C  CG1  . VAL A 1 22  ? 44.49100  -35.99700 -1.65900  1.000 43.46574  ? 22  VAL A CG1  1 
ATOM   307  C  CG2  . VAL A 1 22  ? 46.95700  -36.04800 -2.03300  1.000 45.45282  ? 22  VAL A CG2  1 
ATOM   308  H  H    . VAL A 1 22  ? 46.89900  -34.82200 0.22500   1.000 48.83000  ? 22  VAL A H    1 
ATOM   309  H  HA   . VAL A 1 22  ? 45.16700  -36.84000 0.67900   1.000 48.21000  ? 22  VAL A HA   1 
ATOM   310  H  HB   . VAL A 1 22  ? 45.74400  -37.59600 -1.54800  1.000 50.94000  ? 22  VAL A HB   1 
ATOM   311  H  HG11 . VAL A 1 22  ? 44.37300  -36.05300 -2.62000  1.000 52.16000  ? 22  VAL A HG11 1 
ATOM   312  H  HG12 . VAL A 1 22  ? 43.76100  -36.45100 -1.20900  1.000 52.16000  ? 22  VAL A HG12 1 
ATOM   313  H  HG13 . VAL A 1 22  ? 44.52300  -35.06800 -1.38400  1.000 52.16000  ? 22  VAL A HG13 1 
ATOM   314  H  HG21 . VAL A 1 22  ? 46.82100  -36.16600 -2.98600  1.000 54.54000  ? 22  VAL A HG21 1 
ATOM   315  H  HG22 . VAL A 1 22  ? 47.00600  -35.10300 -1.82000  1.000 54.54000  ? 22  VAL A HG22 1 
ATOM   316  H  HG23 . VAL A 1 22  ? 47.77500  -36.49100 -1.75800  1.000 54.54000  ? 22  VAL A HG23 1 
ATOM   317  N  N    . ASP A 1 23  ? 46.67900  -38.72300 1.03200   1.000 44.16319  ? 23  ASP A N    1 
ATOM   318  C  CA   . ASP A 1 23  ? 47.56900  -39.79300 1.45800   1.000 44.95276  ? 23  ASP A CA   1 
ATOM   319  C  C    . ASP A 1 23  ? 48.10900  -40.46500 0.20800   1.000 45.76865  ? 23  ASP A C    1 
ATOM   320  O  O    . ASP A 1 23  ? 47.33300  -40.92100 -0.64100  1.000 42.87619  ? 23  ASP A O    1 
ATOM   321  C  CB   . ASP A 1 23  ? 46.76800  -40.75900 2.32100   1.000 43.18676  ? 23  ASP A CB   1 
ATOM   322  C  CG   . ASP A 1 23  ? 47.58900  -41.89900 2.87800   1.000 48.91376  ? 23  ASP A CG   1 
ATOM   323  O  OD1  . ASP A 1 23  ? 48.61700  -42.30500 2.28400   1.000 45.82918  ? 23  ASP A OD1  1 
ATOM   324  O  OD2  . ASP A 1 23  ? 47.17000  -42.39800 3.94300   1.000 53.90383  ? 23  ASP A OD2  1 
ATOM   325  H  H    . ASP A 1 23  ? 45.85300  -38.96100 1.03000   1.000 53.00000  ? 23  ASP A H    1 
ATOM   326  H  HA   . ASP A 1 23  ? 48.32000  -39.46700 1.97800   1.000 53.94000  ? 23  ASP A HA   1 
ATOM   327  H  HB2  . ASP A 1 23  ? 46.39300  -40.27100 3.07100   1.000 51.82000  ? 23  ASP A HB2  1 
ATOM   328  H  HB3  . ASP A 1 23  ? 46.05700  -41.14200 1.78400   1.000 51.82000  ? 23  ASP A HB3  1 
ATOM   329  N  N    . MET A 1 24  ? 49.42500  -40.51700 0.07900   1.000 43.94737  ? 24  MET A N    1 
ATOM   330  C  CA   . MET A 1 24  ? 50.01400  -41.05000 -1.13700  1.000 46.12922  ? 24  MET A CA   1 
ATOM   331  C  C    . MET A 1 24  ? 49.94300  -42.56500 -1.22200  1.000 48.24263  ? 24  MET A C    1 
ATOM   332  O  O    . MET A 1 24  ? 50.34200  -43.12800 -2.25000  1.000 46.65296  ? 24  MET A O    1 
ATOM   333  C  CB   . MET A 1 24  ? 51.46000  -40.58400 -1.25800  1.000 43.88947  ? 24  MET A CB   1 
ATOM   334  C  CG   . MET A 1 24  ? 51.56200  -39.08100 -1.32300  1.000 48.02418  ? 24  MET A CG   1 
ATOM   335  S  SD   . MET A 1 24  ? 53.25600  -38.53300 -1.31500  1.000 58.07802  ? 24  MET A SD   1 
ATOM   336  C  CE   . MET A 1 24  ? 53.62300  -38.80000 -3.04000  1.000 53.13795  ? 24  MET A CE   1 
ATOM   337  H  H    . MET A 1 24  ? 49.98900  -40.25300 0.67200   1.000 52.74000  ? 24  MET A H    1 
ATOM   338  H  HA   . MET A 1 24  ? 49.52900  -40.69000 -1.89600  1.000 55.35000  ? 24  MET A HA   1 
ATOM   339  H  HB2  . MET A 1 24  ? 51.95900  -40.88900 -0.48400  1.000 52.66000  ? 24  MET A HB2  1 
ATOM   340  H  HB3  . MET A 1 24  ? 51.84700  -40.95000 -2.06800  1.000 52.66000  ? 24  MET A HB3  1 
ATOM   341  H  HG2  . MET A 1 24  ? 51.14500  -38.76700 -2.14100  1.000 57.63000  ? 24  MET A HG2  1 
ATOM   342  H  HG3  . MET A 1 24  ? 51.11500  -38.69600 -0.55400  1.000 57.63000  ? 24  MET A HG3  1 
ATOM   343  H  HE1  . MET A 1 24  ? 54.54500  -38.55000 -3.20900  1.000 63.76000  ? 24  MET A HE1  1 
ATOM   344  H  HE2  . MET A 1 24  ? 53.49000  -39.73800 -3.24900  1.000 63.76000  ? 24  MET A HE2  1 
ATOM   345  H  HE3  . MET A 1 24  ? 53.02800  -38.25400 -3.57700  1.000 63.76000  ? 24  MET A HE3  1 
ATOM   346  N  N    . SER A 1 25  ? 49.43500  -43.22600 -0.18500  1.000 43.50258  ? 25  SER A N    1 
ATOM   347  C  CA   . SER A 1 25  ? 49.26000  -44.67000 -0.19800  1.000 47.10565  ? 25  SER A CA   1 
ATOM   348  C  C    . SER A 1 25  ? 47.87200  -45.09000 -0.66100  1.000 46.80561  ? 25  SER A C    1 
ATOM   349  O  O    . SER A 1 25  ? 47.62800  -46.28700 -0.83200  1.000 47.05827  ? 25  SER A O    1 
ATOM   350  C  CB   . SER A 1 25  ? 49.52700  -45.24500 1.19500   1.000 45.94498  ? 25  SER A CB   1 
ATOM   351  O  OG   . SER A 1 25  ? 48.43100  -45.00900 2.06100   1.000 52.10888  ? 25  SER A OG   1 
ATOM   352  H  H    . SER A 1 25  ? 49.18200  -42.85300 0.54700   1.000 52.20000  ? 25  SER A H    1 
ATOM   353  H  HA   . SER A 1 25  ? 49.90900  -45.05800 -0.80600  1.000 56.53000  ? 25  SER A HA   1 
ATOM   354  H  HB2  . SER A 1 25  ? 49.66800  -46.20200 1.11900   1.000 55.14000  ? 25  SER A HB2  1 
ATOM   355  H  HB3  . SER A 1 25  ? 50.31800  -44.82200 1.56400   1.000 55.14000  ? 25  SER A HB3  1 
ATOM   356  H  HG   . SER A 1 25  ? 48.27500  -44.18500 2.10800   1.000 62.53000  ? 25  SER A HG   1 
ATOM   357  N  N    . MET A 1 26  ? 46.97100  -44.13700 -0.88000  1.000 48.01628  ? 26  MET A N    1 
ATOM   358  C  CA   . MET A 1 26  ? 45.61500  -44.41000 -1.32400  1.000 43.50258  ? 26  MET A CA   1 
ATOM   359  C  C    . MET A 1 26  ? 45.42700  -43.79900 -2.70700  1.000 43.16044  ? 26  MET A C    1 
ATOM   360  O  O    . MET A 1 26  ? 46.05400  -42.79300 -3.05100  1.000 44.04212  ? 26  MET A O    1 
ATOM   361  C  CB   . MET A 1 26  ? 44.59800  -43.82600 -0.34700  1.000 48.62425  ? 26  MET A CB   1 
ATOM   362  C  CG   . MET A 1 26  ? 44.65000  -44.44400 1.05500   1.000 46.92405  ? 26  MET A CG   1 
ATOM   363  S  SD   . MET A 1 26  ? 43.67600  -43.48500 2.23600   1.000 58.62808  ? 26  MET A SD   1 
ATOM   364  C  CE   . MET A 1 26  ? 42.07600  -44.27700 2.06900   1.000 73.41933  ? 26  MET A CE   1 
ATOM   365  H  H    . MET A 1 26  ? 47.13000  -43.29900 -0.77300  1.000 57.62000  ? 26  MET A H    1 
ATOM   366  H  HA   . MET A 1 26  ? 45.45900  -45.36600 -1.37200  1.000 52.21000  ? 26  MET A HA   1 
ATOM   367  H  HB2  . MET A 1 26  ? 44.76500  -42.87500 -0.25600  1.000 58.35000  ? 26  MET A HB2  1 
ATOM   368  H  HB3  . MET A 1 26  ? 43.70700  -43.97300 -0.70200  1.000 58.35000  ? 26  MET A HB3  1 
ATOM   369  H  HG2  . MET A 1 26  ? 44.29000  -45.34500 1.02200   1.000 56.31000  ? 26  MET A HG2  1 
ATOM   370  H  HG3  . MET A 1 26  ? 45.56900  -44.46600 1.36300   1.000 56.31000  ? 26  MET A HG3  1 
ATOM   371  H  HE1  . MET A 1 26  ? 41.44400  -43.84000 2.66100   1.000 88.11000  ? 26  MET A HE1  1 
ATOM   372  H  HE2  . MET A 1 26  ? 41.77800  -44.19600 1.15000   1.000 88.11000  ? 26  MET A HE2  1 
ATOM   373  H  HE3  . MET A 1 26  ? 42.16000  -45.21300 2.30900   1.000 88.11000  ? 26  MET A HE3  1 
ATOM   374  N  N    . THR A 1 27  ? 44.58000  -44.41800 -3.51400  1.000 43.12359  ? 27  THR A N    1 
ATOM   375  C  CA   . THR A 1 27  ? 44.28300  -43.82000 -4.80800  1.000 41.85765  ? 27  THR A CA   1 
ATOM   376  C  C    . THR A 1 27  ? 43.42900  -42.56700 -4.62300  1.000 39.88899  ? 27  THR A C    1 
ATOM   377  O  O    . THR A 1 27  ? 42.83300  -42.33200 -3.57100  1.000 38.36513  ? 27  THR A O    1 
ATOM   378  C  CB   . THR A 1 27  ? 43.59700  -44.83300 -5.72700  1.000 42.74460  ? 27  THR A CB   1 
ATOM   379  O  OG1  . THR A 1 27  ? 42.24700  -45.02900 -5.29600  1.000 43.07359  ? 27  THR A OG1  1 
ATOM   380  C  CG2  . THR A 1 27  ? 44.33100  -46.15000 -5.74900  1.000 44.62904  ? 27  THR A CG2  1 
ATOM   381  H  H    . THR A 1 27  ? 44.17800  -45.15900 -3.34400  1.000 51.75000  ? 27  THR A H    1 
ATOM   382  H  HA   . THR A 1 27  ? 45.10500  -43.55300 -5.24900  1.000 50.23000  ? 27  THR A HA   1 
ATOM   383  H  HB   . THR A 1 27  ? 43.60000  -44.49100 -6.63500  1.000 51.29000  ? 27  THR A HB   1 
ATOM   384  H  HG1  . THR A 1 27  ? 41.76900  -44.38400 -5.54400  1.000 51.69000  ? 27  THR A HG1  1 
ATOM   385  H  HG21 . THR A 1 27  ? 43.92500  -46.74600 -6.39700  1.000 53.55000  ? 27  THR A HG21 1 
ATOM   386  H  HG22 . THR A 1 27  ? 45.26000  -46.00800 -5.99100  1.000 53.55000  ? 27  THR A HG22 1 
ATOM   387  H  HG23 . THR A 1 27  ? 44.29400  -46.56500 -4.87300  1.000 53.55000  ? 27  THR A HG23 1 
ATOM   388  N  N    . TYR A 1 28  ? 43.40100  -41.73200 -5.66300  1.000 36.89653  ? 28  TYR A N    1 
ATOM   389  C  CA   . TYR A 1 28  ? 42.51500  -40.58000 -5.63000  1.000 37.01233  ? 28  TYR A CA   1 
ATOM   390  C  C    . TYR A 1 28  ? 41.07400  -41.01900 -5.41600  1.000 37.75979  ? 28  TYR A C    1 
ATOM   391  O  O    . TYR A 1 28  ? 40.32400  -40.37500 -4.67200  1.000 37.47818  ? 28  TYR A O    1 
ATOM   392  C  CB   . TYR A 1 28  ? 42.66600  -39.77700 -6.92600  1.000 36.32541  ? 28  TYR A CB   1 
ATOM   393  C  CG   . TYR A 1 28  ? 43.92500  -38.95000 -6.94900  1.000 35.98589  ? 28  TYR A CG   1 
ATOM   394  C  CD1  . TYR A 1 28  ? 44.05700  -37.84800 -6.12300  1.000 34.21463  ? 28  TYR A CD1  1 
ATOM   395  C  CD2  . TYR A 1 28  ? 44.98400  -39.27600 -7.77500  1.000 35.83588  ? 28  TYR A CD2  1 
ATOM   396  C  CE1  . TYR A 1 28  ? 45.20200  -37.08400 -6.12400  1.000 39.33893  ? 28  TYR A CE1  1 
ATOM   397  C  CE2  . TYR A 1 28  ? 46.14600  -38.51900 -7.78400  1.000 37.11761  ? 28  TYR A CE2  1 
ATOM   398  C  CZ   . TYR A 1 28  ? 46.24800  -37.42000 -6.94400  1.000 38.34933  ? 28  TYR A CZ   1 
ATOM   399  O  OH   . TYR A 1 28  ? 47.38700  -36.65000 -6.91400  1.000 37.99140  ? 28  TYR A OH   1 
ATOM   400  H  H    . TYR A 1 28  ? 43.87200  -41.81100 -6.37700  1.000 44.27000  ? 28  TYR A H    1 
ATOM   401  H  HA   . TYR A 1 28  ? 42.76100  -39.99800 -4.89400  1.000 44.41000  ? 28  TYR A HA   1 
ATOM   402  H  HB2  . TYR A 1 28  ? 42.69500  -40.39100 -7.67700  1.000 43.59000  ? 28  TYR A HB2  1 
ATOM   403  H  HB3  . TYR A 1 28  ? 41.90900  -39.17700 -7.01700  1.000 43.59000  ? 28  TYR A HB3  1 
ATOM   404  H  HD1  . TYR A 1 28  ? 43.35700  -37.61900 -5.55600  1.000 41.06000  ? 28  TYR A HD1  1 
ATOM   405  H  HD2  . TYR A 1 28  ? 44.91700  -40.01600 -8.33400  1.000 43.00000  ? 28  TYR A HD2  1 
ATOM   406  H  HE1  . TYR A 1 28  ? 45.26600  -36.34100 -5.56900  1.000 47.21000  ? 28  TYR A HE1  1 
ATOM   407  H  HE2  . TYR A 1 28  ? 46.85000  -38.74500 -8.34800  1.000 44.54000  ? 28  TYR A HE2  1 
ATOM   408  H  HH   . TYR A 1 28  ? 48.06400  -37.13600 -7.02100  1.000 45.59000  ? 28  TYR A HH   1 
ATOM   409  N  N    . GLY A 1 29  ? 40.66800  -42.12100 -6.05200  1.000 39.30998  ? 29  GLY A N    1 
ATOM   410  C  CA   . GLY A 1 29  ? 39.29200  -42.56700 -5.92300  1.000 39.35998  ? 29  GLY A CA   1 
ATOM   411  C  C    . GLY A 1 29  ? 38.91000  -42.89700 -4.49300  1.000 39.56527  ? 29  GLY A C    1 
ATOM   412  O  O    . GLY A 1 29  ? 37.80400  -42.57800 -4.04500  1.000 41.42602  ? 29  GLY A O    1 
ATOM   413  H  H    . GLY A 1 29  ? 41.16300  -42.61500 -6.55300  1.000 47.17000  ? 29  GLY A H    1 
ATOM   414  H  HA2  . GLY A 1 29  ? 38.69900  -41.86800 -6.24200  1.000 47.23000  ? 29  GLY A HA2  1 
ATOM   415  H  HA3  . GLY A 1 29  ? 39.16200  -43.36200 -6.46300  1.000 47.23000  ? 29  GLY A HA3  1 
ATOM   416  N  N    . GLN A 1 30  ? 39.80900  -43.55700 -3.76400  1.000 43.11570  ? 30  GLN A N    1 
ATOM   417  C  CA   . GLN A 1 30  ? 39.51900  -43.89800 -2.37700  1.000 42.75249  ? 30  GLN A CA   1 
ATOM   418  C  C    . GLN A 1 30  ? 39.32600  -42.65900 -1.51700  1.000 44.67641  ? 30  GLN A C    1 
ATOM   419  O  O    . GLN A 1 30  ? 38.76500  -42.75600 -0.42000  1.000 43.98159  ? 30  GLN A O    1 
ATOM   420  C  CB   . GLN A 1 30  ? 40.66100  -44.72400 -1.78300  1.000 45.31333  ? 30  GLN A CB   1 
ATOM   421  C  CG   . GLN A 1 30  ? 40.98400  -45.99800 -2.54300  1.000 54.76446  ? 30  GLN A CG   1 
ATOM   422  C  CD   . GLN A 1 30  ? 42.17800  -46.72600 -1.94300  1.000 54.91185  ? 30  GLN A CD   1 
ATOM   423  O  OE1  . GLN A 1 30  ? 43.25100  -46.79000 -2.54400  1.000 54.47232  ? 30  GLN A OE1  1 
ATOM   424  N  NE2  . GLN A 1 30  ? 41.98500  -47.31000 -0.77000  1.000 64.64986  ? 30  GLN A NE2  1 
ATOM   425  H  H    . GLN A 1 30  ? 40.58100  -43.81300 -4.04500  1.000 51.74000  ? 30  GLN A H    1 
ATOM   426  H  HA   . GLN A 1 30  ? 38.70800  -44.42800 -2.36000  1.000 51.30000  ? 30  GLN A HA   1 
ATOM   427  H  HB2  . GLN A 1 30  ? 41.46300  -44.17900 -1.77100  1.000 54.37000  ? 30  GLN A HB2  1 
ATOM   428  H  HB3  . GLN A 1 30  ? 40.41900  -44.97800 -0.87800  1.000 54.37000  ? 30  GLN A HB3  1 
ATOM   429  H  HG2  . GLN A 1 30  ? 40.21800  -46.59200 -2.51200  1.000 65.72000  ? 30  GLN A HG2  1 
ATOM   430  H  HG3  . GLN A 1 30  ? 41.19400  -45.77600 -3.46400  1.000 65.72000  ? 30  GLN A HG3  1 
ATOM   431  H  HE21 . GLN A 1 30  ? 41.21500  -47.26600 -0.38900  1.000 77.58000  ? 30  GLN A HE21 1 
ATOM   432  H  HE22 . GLN A 1 30  ? 42.62900  -47.73500 -0.38900  1.000 77.58000  ? 30  GLN A HE22 1 
ATOM   433  N  N    . GLN A 1 31  ? 39.80400  -41.50400 -1.97300  1.000 43.24466  ? 31  GLN A N    1 
ATOM   434  C  CA   . GLN A 1 31  ? 39.83000  -40.29400 -1.16100  1.000 40.79700  ? 31  GLN A CA   1 
ATOM   435  C  C    . GLN A 1 31  ? 38.82500  -39.25300 -1.62900  1.000 41.39180  ? 31  GLN A C    1 
ATOM   436  O  O    . GLN A 1 31  ? 38.21800  -38.58000 -0.79500  1.000 40.26009  ? 31  GLN A O    1 
ATOM   437  C  CB   . GLN A 1 31  ? 41.24100  -39.68400 -1.17700  1.000 37.14656  ? 31  GLN A CB   1 
ATOM   438  C  CG   . GLN A 1 31  ? 42.30900  -40.67700 -0.75200  1.000 41.57604  ? 31  GLN A CG   1 
ATOM   439  C  CD   . GLN A 1 31  ? 43.70500  -40.10800 -0.63200  1.000 44.55534  ? 31  GLN A CD   1 
ATOM   440  O  OE1  . GLN A 1 31  ? 43.97000  -39.20400 0.16200   1.000 46.11869  ? 31  GLN A OE1  1 
ATOM   441  N  NE2  . GLN A 1 31  ? 44.59400  -40.57100 -1.51300  1.000 41.23652  ? 31  GLN A NE2  1 
ATOM   442  H  H    . GLN A 1 31  ? 40.12400  -41.39600 -2.76400  1.000 51.89000  ? 31  GLN A H    1 
ATOM   443  H  HA   . GLN A 1 31  ? 39.61800  -40.52000 -0.24200  1.000 48.96000  ? 31  GLN A HA   1 
ATOM   444  H  HB2  . GLN A 1 31  ? 41.44700  -39.38600 -2.07700  1.000 44.58000  ? 31  GLN A HB2  1 
ATOM   445  H  HB3  . GLN A 1 31  ? 41.26700  -38.93200 -0.56400  1.000 44.58000  ? 31  GLN A HB3  1 
ATOM   446  H  HG2  . GLN A 1 31  ? 42.06700  -41.03500 0.11700   1.000 49.89000  ? 31  GLN A HG2  1 
ATOM   447  H  HG3  . GLN A 1 31  ? 42.34300  -41.39200 -1.40700  1.000 49.89000  ? 31  GLN A HG3  1 
ATOM   448  H  HE21 . GLN A 1 31  ? 44.35600  -41.15500 -2.09700  1.000 49.48000  ? 31  GLN A HE21 1 
ATOM   449  H  HE22 . GLN A 1 31  ? 45.40500  -40.28500 -1.49600  1.000 49.48000  ? 31  GLN A HE22 1 
ATOM   450  N  N    . PHE A 1 32  ? 38.62700  -39.12700 -2.95100  1.000 40.75225  ? 32  PHE A N    1 
ATOM   451  C  CA   . PHE A 1 32  ? 37.75800  -38.11300 -3.52600  1.000 37.92823  ? 32  PHE A CA   1 
ATOM   452  C  C    . PHE A 1 32  ? 36.56300  -38.66000 -4.30300  1.000 40.46538  ? 32  PHE A C    1 
ATOM   453  O  O    . PHE A 1 32  ? 35.69200  -37.87500 -4.70400  1.000 39.37314  ? 32  PHE A O    1 
ATOM   454  C  CB   . PHE A 1 32  ? 38.52200  -37.22500 -4.52300  1.000 36.67282  ? 32  PHE A CB   1 
ATOM   455  C  CG   . PHE A 1 32  ? 39.68900  -36.47800 -3.96300  1.000 37.57819  ? 32  PHE A CG   1 
ATOM   456  C  CD1  . PHE A 1 32  ? 39.73600  -36.05600 -2.64600  1.000 39.92321  ? 32  PHE A CD1  1 
ATOM   457  C  CD2  . PHE A 1 32  ? 40.74600  -36.16300 -4.80400  1.000 43.02884  ? 32  PHE A CD2  1 
ATOM   458  C  CE1  . PHE A 1 32  ? 40.82300  -35.35500 -2.18300  1.000 39.39946  ? 32  PHE A CE1  1 
ATOM   459  C  CE2  . PHE A 1 32  ? 41.83200  -35.46700 -4.34400  1.000 43.27624  ? 32  PHE A CE2  1 
ATOM   460  C  CZ   . PHE A 1 32  ? 41.87300  -35.06100 -3.03800  1.000 43.34730  ? 32  PHE A CZ   1 
ATOM   461  H  H    . PHE A 1 32  ? 38.99700  -39.63200 -3.54000  1.000 48.90000  ? 32  PHE A H    1 
ATOM   462  H  HA   . PHE A 1 32  ? 37.44200  -37.57900 -2.78100  1.000 45.51000  ? 32  PHE A HA   1 
ATOM   463  H  HB2  . PHE A 1 32  ? 38.85700  -37.78800 -5.23800  1.000 44.01000  ? 32  PHE A HB2  1 
ATOM   464  H  HB3  . PHE A 1 32  ? 37.90400  -36.56700 -4.88000  1.000 44.01000  ? 32  PHE A HB3  1 
ATOM   465  H  HD1  . PHE A 1 32  ? 39.02900  -36.24700 -2.07200  1.000 47.91000  ? 32  PHE A HD1  1 
ATOM   466  H  HD2  . PHE A 1 32  ? 40.71700  -36.42800 -5.69500  1.000 51.63000  ? 32  PHE A HD2  1 
ATOM   467  H  HE1  . PHE A 1 32  ? 40.85500  -35.07900 -1.29500  1.000 47.28000  ? 32  PHE A HE1  1 
ATOM   468  H  HE2  . PHE A 1 32  ? 42.53900  -35.27100 -4.91700  1.000 51.93000  ? 32  PHE A HE2  1 
ATOM   469  H  HZ   . PHE A 1 32  ? 42.60800  -34.58600 -2.72300  1.000 52.02000  ? 32  PHE A HZ   1 
ATOM   470  N  N    . GLY A 1 33  ? 36.51100  -39.95500 -4.57600  1.000 35.56742  ? 33  GLY A N    1 
ATOM   471  C  CA   . GLY A 1 33  ? 35.65300  -40.45900 -5.62400  1.000 39.63107  ? 33  GLY A CA   1 
ATOM   472  C  C    . GLY A 1 33  ? 36.29700  -40.21100 -6.97500  1.000 37.52555  ? 33  GLY A C    1 
ATOM   473  O  O    . GLY A 1 33  ? 37.49900  -39.93600 -7.06400  1.000 37.82559  ? 33  GLY A O    1 
ATOM   474  H  H    . GLY A 1 33  ? 36.96500  -40.55900 -4.16600  1.000 42.68000  ? 33  GLY A H    1 
ATOM   475  H  HA2  . GLY A 1 33  ? 35.51400  -41.41200 -5.50900  1.000 47.56000  ? 33  GLY A HA2  1 
ATOM   476  H  HA3  . GLY A 1 33  ? 34.79400  -40.00900 -5.59500  1.000 47.56000  ? 33  GLY A HA3  1 
ATOM   477  N  N    . PRO A 1 34  ? 35.52200  -40.30500 -8.05200  1.000 35.10421  ? 34  PRO A N    1 
ATOM   478  C  CA   . PRO A 1 34  ? 36.09700  -40.09100 -9.38600  1.000 34.12514  ? 34  PRO A CA   1 
ATOM   479  C  C    . PRO A 1 34  ? 36.83700  -38.76400 -9.47400  1.000 32.17754  ? 34  PRO A C    1 
ATOM   480  O  O    . PRO A 1 34  ? 36.31900  -37.71200 -9.09000  1.000 34.93840  ? 34  PRO A O    1 
ATOM   481  C  CB   . PRO A 1 34  ? 34.87300  -40.13000 -10.30900 1.000 35.77008  ? 34  PRO A CB   1 
ATOM   482  C  CG   . PRO A 1 34  ? 33.86700  -40.99100 -9.55200  1.000 38.38881  ? 34  PRO A CG   1 
ATOM   483  C  CD   . PRO A 1 34  ? 34.08500  -40.63400 -8.10000  1.000 35.93589  ? 34  PRO A CD   1 
ATOM   484  H  HA   . PRO A 1 34  ? 36.70200  -40.81400 -9.61600  1.000 40.95000  ? 34  PRO A HA   1 
ATOM   485  H  HB2  . PRO A 1 34  ? 34.53200  -39.23300 -10.44900 1.000 42.92000  ? 34  PRO A HB2  1 
ATOM   486  H  HB3  . PRO A 1 34  ? 35.10900  -40.53100 -11.16000 1.000 42.92000  ? 34  PRO A HB3  1 
ATOM   487  H  HG2  . PRO A 1 34  ? 32.96500  -40.77400 -9.83300  1.000 46.07000  ? 34  PRO A HG2  1 
ATOM   488  H  HG3  . PRO A 1 34  ? 34.04700  -41.93100 -9.71100  1.000 46.07000  ? 34  PRO A HG3  1 
ATOM   489  H  HD2  . PRO A 1 34  ? 33.54600  -39.86900 -7.84600  1.000 43.12000  ? 34  PRO A HD2  1 
ATOM   490  H  HD3  . PRO A 1 34  ? 33.88300  -41.38800 -7.52400  1.000 43.12000  ? 34  PRO A HD3  1 
ATOM   491  N  N    . THR A 1 35  ? 38.06900  -38.82200 -9.98500  1.000 32.76709  ? 35  THR A N    1 
ATOM   492  C  CA   . THR A 1 35  ? 38.99200  -37.69400 -9.98700  1.000 31.62748  ? 35  THR A CA   1 
ATOM   493  C  C    . THR A 1 35  ? 39.68300  -37.59500 -11.33600 1.000 32.20912  ? 35  THR A C    1 
ATOM   494  O  O    . THR A 1 35  ? 40.09700  -38.61100 -11.90100 1.000 32.34072  ? 35  THR A O    1 
ATOM   495  C  CB   . THR A 1 35  ? 40.05100  -37.85300 -8.89100  1.000 35.19106  ? 35  THR A CB   1 
ATOM   496  O  OG1  . THR A 1 35  ? 39.40000  -38.04600 -7.63800  1.000 34.48571  ? 35  THR A OG1  1 
ATOM   497  C  CG2  . THR A 1 35  ? 40.92100  -36.62700 -8.80200  1.000 34.33306  ? 35  THR A CG2  1 
ATOM   498  H  H    . THR A 1 35  ? 38.40100  -39.52900 -10.34700 1.000 39.32000  ? 35  THR A H    1 
ATOM   499  H  HA   . THR A 1 35  ? 38.49500  -36.87400 -9.83800  1.000 37.95000  ? 35  THR A HA   1 
ATOM   500  H  HB   . THR A 1 35  ? 40.61600  -38.61400 -9.09800  1.000 42.23000  ? 35  THR A HB   1 
ATOM   501  H  HG1  . THR A 1 35  ? 38.93100  -38.74300 -7.66300  1.000 41.38000  ? 35  THR A HG1  1 
ATOM   502  H  HG21 . THR A 1 35  ? 41.49200  -36.68100 -8.02000  1.000 41.20000  ? 35  THR A HG21 1 
ATOM   503  H  HG22 . THR A 1 35  ? 41.47700  -36.55600 -9.59400  1.000 41.20000  ? 35  THR A HG22 1 
ATOM   504  H  HG23 . THR A 1 35  ? 40.36800  -35.83300 -8.73400  1.000 41.20000  ? 35  THR A HG23 1 
ATOM   505  N  N    . TYR A 1 36  ? 39.81400  -36.36800 -11.83700 1.000 33.09607  ? 36  TYR A N    1 
ATOM   506  C  CA   . TYR A 1 36  ? 40.34200  -36.12300 -13.16700 1.000 31.78013  ? 36  TYR A CA   1 
ATOM   507  C  C    . TYR A 1 36  ? 41.37600  -35.01300 -13.11800 1.000 35.62269  ? 36  TYR A C    1 
ATOM   508  O  O    . TYR A 1 36  ? 41.24500  -34.04900 -12.35300 1.000 32.78814  ? 36  TYR A O    1 
ATOM   509  C  CB   . TYR A 1 36  ? 39.22000  -35.73600 -14.16000 1.000 30.93792  ? 36  TYR A CB   1 
ATOM   510  C  CG   . TYR A 1 36  ? 38.10000  -36.73400 -14.23300 1.000 31.10110  ? 36  TYR A CG   1 
ATOM   511  C  CD1  . TYR A 1 36  ? 37.04600  -36.70600 -13.33100 1.000 32.84868  ? 36  TYR A CD1  1 
ATOM   512  C  CD2  . TYR A 1 36  ? 38.08700  -37.69700 -15.22500 1.000 31.51957  ? 36  TYR A CD2  1 
ATOM   513  C  CE1  . TYR A 1 36  ? 36.02300  -37.63400 -13.41700 1.000 33.93828  ? 36  TYR A CE1  1 
ATOM   514  C  CE2  . TYR A 1 36  ? 37.08400  -38.60700 -15.32000 1.000 34.29359  ? 36  TYR A CE2  1 
ATOM   515  C  CZ   . TYR A 1 36  ? 36.05000  -38.57400 -14.42800 1.000 35.13842  ? 36  TYR A CZ   1 
ATOM   516  O  OH   . TYR A 1 36  ? 35.05600  -39.52000 -14.57700 1.000 39.80214  ? 36  TYR A OH   1 
ATOM   517  H  H    . TYR A 1 36  ? 39.59700  -35.65100 -11.41400 1.000 39.71000  ? 36  TYR A H    1 
ATOM   518  H  HA   . TYR A 1 36  ? 40.77600  -36.92900 -13.48800 1.000 38.14000  ? 36  TYR A HA   1 
ATOM   519  H  HB2  . TYR A 1 36  ? 38.84100  -34.88600 -13.88500 1.000 37.12000  ? 36  TYR A HB2  1 
ATOM   520  H  HB3  . TYR A 1 36  ? 39.60300  -35.65600 -15.04700 1.000 37.12000  ? 36  TYR A HB3  1 
ATOM   521  H  HD1  . TYR A 1 36  ? 37.02600  -36.05900 -12.66300 1.000 39.42000  ? 36  TYR A HD1  1 
ATOM   522  H  HD2  . TYR A 1 36  ? 38.78200  -37.72300 -15.84200 1.000 37.82000  ? 36  TYR A HD2  1 
ATOM   523  H  HE1  . TYR A 1 36  ? 35.32700  -37.62500 -12.80100 1.000 40.72000  ? 36  TYR A HE1  1 
ATOM   524  H  HE2  . TYR A 1 36  ? 37.10000  -39.25000 -15.99100 1.000 41.15000  ? 36  TYR A HE2  1 
ATOM   525  H  HH   . TYR A 1 36  ? 34.48700  -39.43700 -13.96500 1.000 47.76000  ? 36  TYR A HH   1 
ATOM   526  N  N    . LEU A 1 37  ? 42.41200  -35.16900 -13.93400 1.000 33.06975  ? 37  LEU A N    1 
ATOM   527  C  CA   . LEU A 1 37  ? 43.50600  -34.21200 -14.06300 1.000 34.75680  ? 37  LEU A CA   1 
ATOM   528  C  C    . LEU A 1 37  ? 43.46500  -33.72000 -15.50700 1.000 38.19142  ? 37  LEU A C    1 
ATOM   529  O  O    . LEU A 1 37  ? 43.92600  -34.41900 -16.42000 1.000 37.22288  ? 37  LEU A O    1 
ATOM   530  C  CB   . LEU A 1 37  ? 44.83000  -34.87200 -13.71500 1.000 36.65439  ? 37  LEU A CB   1 
ATOM   531  C  CG   . LEU A 1 37  ? 46.07400  -34.00000 -13.82600 1.000 41.13125  ? 37  LEU A CG   1 
ATOM   532  C  CD1  . LEU A 1 37  ? 45.85400  -32.72500 -13.03600 1.000 36.18065  ? 37  LEU A CD1  1 
ATOM   533  C  CD2  . LEU A 1 37  ? 47.30300  -34.73400 -13.33600 1.000 40.64961  ? 37  LEU A CD2  1 
ATOM   534  H  H    . LEU A 1 37  ? 42.50900  -35.85400 -14.44600 1.000 39.68000  ? 37  LEU A H    1 
ATOM   535  H  HA   . LEU A 1 37  ? 43.38800  -33.45500 -13.46800 1.000 41.71000  ? 37  LEU A HA   1 
ATOM   536  H  HB2  . LEU A 1 37  ? 44.78000  -35.18100 -12.79700 1.000 43.99000  ? 37  LEU A HB2  1 
ATOM   537  H  HB3  . LEU A 1 37  ? 44.95600  -35.62600 -14.31300 1.000 43.99000  ? 37  LEU A HB3  1 
ATOM   538  H  HG   . LEU A 1 37  ? 46.23500  -33.77500 -14.75600 1.000 49.36000  ? 37  LEU A HG   1 
ATOM   539  H  HD11 . LEU A 1 37  ? 46.71000  -32.29900 -12.87900 1.000 43.42000  ? 37  LEU A HD11 1 
ATOM   540  H  HD12 . LEU A 1 37  ? 45.27800  -32.13400 -13.54500 1.000 43.42000  ? 37  LEU A HD12 1 
ATOM   541  H  HD13 . LEU A 1 37  ? 45.43500  -32.94700 -12.18900 1.000 43.42000  ? 37  LEU A HD13 1 
ATOM   542  H  HD21 . LEU A 1 37  ? 48.07900  -34.16300 -13.45000 1.000 48.78000  ? 37  LEU A HD21 1 
ATOM   543  H  HD22 . LEU A 1 37  ? 47.18800  -34.95100 -12.39700 1.000 48.78000  ? 37  LEU A HD22 1 
ATOM   544  H  HD23 . LEU A 1 37  ? 47.41200  -35.54800 -13.85200 1.000 48.78000  ? 37  LEU A HD23 1 
ATOM   545  N  N    . ASP A 1 38  ? 42.88700  -32.53600 -15.71400 1.000 39.23365  ? 38  ASP A N    1 
ATOM   546  C  CA   . ASP A 1 38  ? 42.70000  -31.97000 -17.05800 1.000 36.99391  ? 38  ASP A CA   1 
ATOM   547  C  C    . ASP A 1 38  ? 42.13700  -33.01300 -18.02000 1.000 39.52579  ? 38  ASP A C    1 
ATOM   548  O  O    . ASP A 1 38  ? 42.64600  -33.22500 -19.13400 1.000 37.13866  ? 38  ASP A O    1 
ATOM   549  C  CB   . ASP A 1 38  ? 44.00800  -31.38300 -17.59800 1.000 42.52878  ? 38  ASP A CB   1 
ATOM   550  C  CG   . ASP A 1 38  ? 43.80200  -30.57100 -18.88300 1.000 53.04583  ? 38  ASP A CG   1 
ATOM   551  O  OD1  . ASP A 1 38  ? 42.77000  -29.86700 -18.98800 1.000 47.89522  ? 38  ASP A OD1  1 
ATOM   552  O  OD2  . ASP A 1 38  ? 44.65500  -30.65000 -19.79300 1.000 55.18556  ? 38  ASP A OD2  1 
ATOM   553  H  H    . ASP A 1 38  ? 42.59000  -32.03100 -15.08500 1.000 47.08000  ? 38  ASP A H    1 
ATOM   554  H  HA   . ASP A 1 38  ? 42.05300  -31.25000 -16.99200 1.000 44.39000  ? 38  ASP A HA   1 
ATOM   555  H  HB2  . ASP A 1 38  ? 44.39200  -30.79500 -16.92900 1.000 51.04000  ? 38  ASP A HB2  1 
ATOM   556  H  HB3  . ASP A 1 38  ? 44.62300  -32.10700 -17.79500 1.000 51.04000  ? 38  ASP A HB3  1 
ATOM   557  N  N    . GLY A 1 39  ? 41.05600  -33.66600 -17.58500 1.000 34.22779  ? 39  GLY A N    1 
ATOM   558  C  CA   . GLY A 1 39  ? 40.35800  -34.63300 -18.40300 1.000 35.91746  ? 39  GLY A CA   1 
ATOM   559  C  C    . GLY A 1 39  ? 40.79100  -36.06800 -18.20900 1.000 34.12778  ? 39  GLY A C    1 
ATOM   560  O  O    . GLY A 1 39  ? 39.99900  -36.98100 -18.47200 1.000 37.15445  ? 39  GLY A O    1 
ATOM   561  H  H    . GLY A 1 39  ? 40.71000  -33.55700 -16.80600 1.000 41.07000  ? 39  GLY A H    1 
ATOM   562  H  HA2  . GLY A 1 39  ? 39.41000  -34.58100 -18.20300 1.000 43.10000  ? 39  GLY A HA2  1 
ATOM   563  H  HA3  . GLY A 1 39  ? 40.49600  -34.40700 -19.33600 1.000 43.10000  ? 39  GLY A HA3  1 
ATOM   564  N  N    . ALA A 1 40  ? 42.02100  -36.29700 -17.75900 1.000 34.61994  ? 40  ALA A N    1 
ATOM   565  C  CA   . ALA A 1 40  ? 42.52300  -37.64900 -17.57300 1.000 32.92763  ? 40  ALA A CA   1 
ATOM   566  C  C    . ALA A 1 40  ? 41.96900  -38.22300 -16.27800 1.000 34.83576  ? 40  ALA A C    1 
ATOM   567  O  O    . ALA A 1 40  ? 41.97600  -37.55300 -15.24600 1.000 35.13842  ? 40  ALA A O    1 
ATOM   568  C  CB   . ALA A 1 40  ? 44.05000  -37.65000 -17.54500 1.000 36.30962  ? 40  ALA A CB   1 
ATOM   569  H  H    . ALA A 1 40  ? 42.58500  -35.68200 -17.55400 1.000 41.54000  ? 40  ALA A H    1 
ATOM   570  H  HA   . ALA A 1 40  ? 42.23600  -38.21100 -18.31000 1.000 39.51000  ? 40  ALA A HA   1 
ATOM   571  H  HB1  . ALA A 1 40  ? 44.36300  -38.56100 -17.42800 1.000 43.57000  ? 40  ALA A HB1  1 
ATOM   572  H  HB2  . ALA A 1 40  ? 44.38100  -37.29200 -18.38300 1.000 43.57000  ? 40  ALA A HB2  1 
ATOM   573  H  HB3  . ALA A 1 40  ? 44.35300  -37.09900 -16.80700 1.000 43.57000  ? 40  ALA A HB3  1 
ATOM   574  N  N    . ASP A 1 41  ? 41.47800  -39.45900 -16.34300 1.000 35.91746  ? 41  ASP A N    1 
ATOM   575  C  CA   . ASP A 1 41  ? 40.85600  -40.11700 -15.19700 1.000 32.95921  ? 41  ASP A CA   1 
ATOM   576  C  C    . ASP A 1 41  ? 41.95600  -40.68800 -14.31600 1.000 34.58573  ? 41  ASP A C    1 
ATOM   577  O  O    . ASP A 1 41  ? 42.61300  -41.66100 -14.69500 1.000 38.69148  ? 41  ASP A O    1 
ATOM   578  C  CB   . ASP A 1 41  ? 39.90700  -41.19900 -15.69900 1.000 38.25195  ? 41  ASP A CB   1 
ATOM   579  C  CG   . ASP A 1 41  ? 39.17000  -41.90700 -14.59000 1.000 40.09691  ? 41  ASP A CG   1 
ATOM   580  O  OD1  . ASP A 1 41  ? 39.52200  -41.73800 -13.40000 1.000 38.36249  ? 41  ASP A OD1  1 
ATOM   581  O  OD2  . ASP A 1 41  ? 38.21800  -42.64800 -14.92300 1.000 40.34168  ? 41  ASP A OD2  1 
ATOM   582  H  H    . ASP A 1 41  ? 41.49300  -39.94500 -17.05200 1.000 43.10000  ? 41  ASP A H    1 
ATOM   583  H  HA   . ASP A 1 41  ? 40.34800  -39.48300 -14.66600 1.000 39.55000  ? 41  ASP A HA   1 
ATOM   584  H  HB2  . ASP A 1 41  ? 39.24800  -40.79200 -16.28300 1.000 45.90000  ? 41  ASP A HB2  1 
ATOM   585  H  HB3  . ASP A 1 41  ? 40.41900  -41.86200 -16.18800 1.000 45.90000  ? 41  ASP A HB3  1 
ATOM   586  N  N    . VAL A 1 42  ? 42.15700  -40.09100 -13.14500 1.000 37.62820  ? 42  VAL A N    1 
ATOM   587  C  CA   . VAL A 1 42  ? 43.17800  -40.53600 -12.20100 1.000 38.04667  ? 42  VAL A CA   1 
ATOM   588  C  C    . VAL A 1 42  ? 42.55100  -41.24800 -11.00200 1.000 38.06772  ? 42  VAL A C    1 
ATOM   589  O  O    . VAL A 1 42  ? 43.20100  -41.40800 -9.96300  1.000 36.19908  ? 42  VAL A O    1 
ATOM   590  C  CB   . VAL A 1 42  ? 44.06700  -39.36800 -11.73200 1.000 35.82272  ? 42  VAL A CB   1 
ATOM   591  C  CG1  . VAL A 1 42  ? 44.87300  -38.81200 -12.89800 1.000 40.01006  ? 42  VAL A CG1  1 
ATOM   592  C  CG2  . VAL A 1 42  ? 43.23800  -38.28900 -11.04200 1.000 36.81757  ? 42  VAL A CG2  1 
ATOM   593  H  H    . VAL A 1 42  ? 41.70600  -39.41300 -12.87000 1.000 45.15000  ? 42  VAL A H    1 
ATOM   594  H  HA   . VAL A 1 42  ? 43.74200  -41.17400 -12.66500 1.000 45.65000  ? 42  VAL A HA   1 
ATOM   595  H  HB   . VAL A 1 42  ? 44.69900  -39.69700 -11.07400 1.000 42.99000  ? 42  VAL A HB   1 
ATOM   596  H  HG11 . VAL A 1 42  ? 45.42700  -38.08300 -12.57900 1.000 48.01000  ? 42  VAL A HG11 1 
ATOM   597  H  HG12 . VAL A 1 42  ? 45.43100  -39.51800 -13.26100 1.000 48.01000  ? 42  VAL A HG12 1 
ATOM   598  H  HG13 . VAL A 1 42  ? 44.26200  -38.49000 -13.57900 1.000 48.01000  ? 42  VAL A HG13 1 
ATOM   599  H  HG21 . VAL A 1 42  ? 43.81800  -37.55000 -10.80300 1.000 44.18000  ? 42  VAL A HG21 1 
ATOM   600  H  HG22 . VAL A 1 42  ? 42.54700  -37.98400 -11.65100 1.000 44.18000  ? 42  VAL A HG22 1 
ATOM   601  H  HG23 . VAL A 1 42  ? 42.83300  -38.66400 -10.24400 1.000 44.18000  ? 42  VAL A HG23 1 
ATOM   602  N  N    . THR A 1 43  ? 41.29900  -41.68000 -11.13300 1.000 38.19668  ? 43  THR A N    1 
ATOM   603  C  CA   . THR A 1 43  ? 40.60000  -42.29700 -10.01400 1.000 37.55450  ? 43  THR A CA   1 
ATOM   604  C  C    . THR A 1 43  ? 41.38500  -43.46700 -9.44600  1.000 39.68634  ? 43  THR A C    1 
ATOM   605  O  O    . THR A 1 43  ? 41.45900  -43.64000 -8.22400  1.000 38.85992  ? 43  THR A O    1 
ATOM   606  C  CB   . THR A 1 43  ? 39.21500  -42.75200 -10.46800 1.000 37.57819  ? 43  THR A CB   1 
ATOM   607  O  OG1  . THR A 1 43  ? 38.48800  -41.61700 -10.94200 1.000 36.93864  ? 43  THR A OG1  1 
ATOM   608  C  CG2  . THR A 1 43  ? 38.44700  -43.37300 -9.31600  1.000 38.42303  ? 43  THR A CG2  1 
ATOM   609  H  H    . THR A 1 43  ? 40.83400  -41.62600 -11.85500 1.000 45.84000  ? 43  THR A H    1 
ATOM   610  H  HA   . THR A 1 43  ? 40.49300  -41.64300 -9.30700  1.000 45.06000  ? 43  THR A HA   1 
ATOM   611  H  HB   . THR A 1 43  ? 39.30500  -43.41600 -11.16900 1.000 45.10000  ? 43  THR A HB   1 
ATOM   612  H  HG1  . THR A 1 43  ? 38.88800  -41.27300 -11.59600 1.000 44.32000  ? 43  THR A HG1  1 
ATOM   613  H  HG21 . THR A 1 43  ? 37.52400  -43.52300 -9.57600  1.000 46.11000  ? 43  THR A HG21 1 
ATOM   614  H  HG22 . THR A 1 43  ? 38.84700  -44.22200 -9.07000  1.000 46.11000  ? 43  THR A HG22 1 
ATOM   615  H  HG23 . THR A 1 43  ? 38.46500  -42.78200 -8.54800  1.000 46.11000  ? 43  THR A HG23 1 
ATOM   616  N  N    . LYS A 1 44  ? 41.99000  -44.26800 -10.31600 1.000 38.93098  ? 44  LYS A N    1 
ATOM   617  C  CA   . LYS A 1 44  ? 42.63700  -45.51700 -9.93400  1.000 43.07095  ? 44  LYS A CA   1 
ATOM   618  C  C    . LYS A 1 44  ? 44.12600  -45.34800 -9.64700  1.000 44.00791  ? 44  LYS A C    1 
ATOM   619  O  O    . LYS A 1 44  ? 44.82500  -46.34200 -9.41200  1.000 44.07107  ? 44  LYS A O    1 
ATOM   620  C  CB   . LYS A 1 44  ? 42.44400  -46.53900 -11.05700 1.000 46.96616  ? 44  LYS A CB   1 
ATOM   621  C  CG   . LYS A 1 44  ? 41.06900  -47.18600 -11.08100 1.000 53.26165  ? 44  LYS A CG   1 
ATOM   622  C  CD   . LYS A 1 44  ? 41.04400  -48.36200 -12.05700 1.000 70.75848  ? 44  LYS A CD   1 
ATOM   623  C  CE   . LYS A 1 44  ? 39.65600  -48.60200 -12.63900 1.000 92.73743  ? 44  LYS A CE   1 
ATOM   624  N  NZ   . LYS A 1 44  ? 39.69800  -49.02000 -14.07200 1.000 118.81425 ? 44  LYS A NZ   1 
ATOM   625  H  H    . LYS A 1 44  ? 42.03900  -44.10400 -11.15800 1.000 46.72000  ? 44  LYS A H    1 
ATOM   626  H  HA   . LYS A 1 44  ? 42.22200  -45.85600 -9.12600  1.000 51.69000  ? 44  LYS A HA   1 
ATOM   627  H  HB2  . LYS A 1 44  ? 42.57300  -46.09200 -11.90900 1.000 56.36000  ? 44  LYS A HB2  1 
ATOM   628  H  HB3  . LYS A 1 44  ? 43.09900  -47.24600 -10.95000 1.000 56.36000  ? 44  LYS A HB3  1 
ATOM   629  H  HG2  . LYS A 1 44  ? 40.85000  -47.51500 -10.19600 1.000 63.92000  ? 44  LYS A HG2  1 
ATOM   630  H  HG3  . LYS A 1 44  ? 40.40900  -46.53500 -11.36600 1.000 63.92000  ? 44  LYS A HG3  1 
ATOM   631  H  HD2  . LYS A 1 44  ? 41.65100  -48.17900 -12.79200 1.000 84.91000  ? 44  LYS A HD2  1 
ATOM   632  H  HD3  . LYS A 1 44  ? 41.31900  -49.16700 -11.59200 1.000 84.91000  ? 44  LYS A HD3  1 
ATOM   633  H  HE2  . LYS A 1 44  ? 39.21700  -49.30500 -12.13400 1.000 111.29000 ? 44  LYS A HE2  1 
ATOM   634  H  HE3  . LYS A 1 44  ? 39.14100  -47.78200 -12.58100 1.000 111.29000 ? 44  LYS A HE3  1 
ATOM   635  H  HZ1  . LYS A 1 44  ? 38.87100  -49.13500 -14.38100 1.000 142.58000 ? 44  LYS A HZ1  1 
ATOM   636  H  HZ2  . LYS A 1 44  ? 40.10400  -48.39600 -14.56000 1.000 142.58000 ? 44  LYS A HZ2  1 
ATOM   637  H  HZ3  . LYS A 1 44  ? 40.14600  -49.78500 -14.15300 1.000 142.58000 ? 44  LYS A HZ3  1 
ATOM   638  N  N    . ILE A 1 45  ? 44.62000  -44.12000 -9.65600  1.000 40.98649  ? 45  ILE A N    1 
ATOM   639  C  CA   . ILE A 1 45  ? 46.04300  -43.82100 -9.56500  1.000 42.04978  ? 45  ILE A CA   1 
ATOM   640  C  C    . ILE A 1 45  ? 46.33100  -43.27800 -8.17700  1.000 39.90215  ? 45  ILE A C    1 
ATOM   641  O  O    . ILE A 1 45  ? 45.47000  -42.66300 -7.53900  1.000 41.70500  ? 45  ILE A O    1 
ATOM   642  C  CB   . ILE A 1 45  ? 46.40700  -42.81900 -10.68300 1.000 45.26595  ? 45  ILE A CB   1 
ATOM   643  C  CG1  . ILE A 1 45  ? 46.71000  -43.59600 -11.97200 1.000 47.77678  ? 45  ILE A CG1  1 
ATOM   644  C  CG2  . ILE A 1 45  ? 47.58000  -41.95100 -10.30800 1.000 46.41872  ? 45  ILE A CG2  1 
ATOM   645  C  CD1  . ILE A 1 45  ? 46.30000  -42.87600 -13.22200 1.000 57.13843  ? 45  ILE A CD1  1 
ATOM   646  H  H    . ILE A 1 45  ? 44.13200  -43.41400 -9.71700  1.000 49.18000  ? 45  ILE A H    1 
ATOM   647  H  HA   . ILE A 1 45  ? 46.59000  -44.61600 -9.66300  1.000 50.46000  ? 45  ILE A HA   1 
ATOM   648  H  HB   . ILE A 1 45  ? 45.64800  -42.22900 -10.81800 1.000 54.32000  ? 45  ILE A HB   1 
ATOM   649  H  HG12 . ILE A 1 45  ? 47.66500  -43.75600 -12.02200 1.000 57.33000  ? 45  ILE A HG12 1 
ATOM   650  H  HG13 . ILE A 1 45  ? 46.23300  -44.44000 -11.94600 1.000 57.33000  ? 45  ILE A HG13 1 
ATOM   651  H  HG21 . ILE A 1 45  ? 47.78500  -41.36000 -11.04900 1.000 55.70000  ? 45  ILE A HG21 1 
ATOM   652  H  HG22 . ILE A 1 45  ? 47.34800  -41.43000 -9.52300  1.000 55.70000  ? 45  ILE A HG22 1 
ATOM   653  H  HG23 . ILE A 1 45  ? 48.34300  -42.51700 -10.11500 1.000 55.70000  ? 45  ILE A HG23 1 
ATOM   654  H  HD11 . ILE A 1 45  ? 46.52500  -43.42500 -13.99000 1.000 68.57000  ? 45  ILE A HD11 1 
ATOM   655  H  HD12 . ILE A 1 45  ? 45.34300  -42.71900 -13.19700 1.000 68.57000  ? 45  ILE A HD12 1 
ATOM   656  H  HD13 . ILE A 1 45  ? 46.77400  -42.03100 -13.27000 1.000 68.57000  ? 45  ILE A HD13 1 
ATOM   657  N  N    . LYS A 1 46  ? 47.55300  -43.54500 -7.68700  1.000 44.82906  ? 46  LYS A N    1 
ATOM   658  C  CA   . LYS A 1 46  ? 47.93600  -42.97400 -6.40500  1.000 43.35257  ? 46  LYS A CA   1 
ATOM   659  C  C    . LYS A 1 46  ? 48.70300  -41.67500 -6.62000  1.000 42.62353  ? 46  LYS A C    1 
ATOM   660  O  O    . LYS A 1 46  ? 49.38600  -41.51600 -7.63400  1.000 47.76625  ? 46  LYS A O    1 
ATOM   661  C  CB   . LYS A 1 46  ? 48.80000  -43.95600 -5.60900  1.000 45.25543  ? 46  LYS A CB   1 
ATOM   662  C  CG   . LYS A 1 46  ? 48.04300  -45.17200 -5.07100  1.000 44.89749  ? 46  LYS A CG   1 
ATOM   663  C  CD   . LYS A 1 46  ? 48.91600  -45.94900 -4.09100  1.000 48.13209  ? 46  LYS A CD   1 
ATOM   664  C  CE   . LYS A 1 46  ? 48.51900  -47.41900 -3.92900  1.000 54.79604  ? 46  LYS A CE   1 
ATOM   665  N  NZ   . LYS A 1 46  ? 47.11500  -47.63600 -3.45800  1.000 63.61289  ? 46  LYS A NZ   1 
ATOM   666  H  H    . LYS A 1 46  ? 48.14800  -44.03500 -8.06900  1.000 53.80000  ? 46  LYS A H    1 
ATOM   667  H  HA   . LYS A 1 46  ? 47.14500  -42.78400 -5.87700  1.000 52.02000  ? 46  LYS A HA   1 
ATOM   668  H  HB2  . LYS A 1 46  ? 49.50800  -44.28300 -6.18600  1.000 54.31000  ? 46  LYS A HB2  1 
ATOM   669  H  HB3  . LYS A 1 46  ? 49.18000  -43.48800 -4.84900  1.000 54.31000  ? 46  LYS A HB3  1 
ATOM   670  H  HG2  . LYS A 1 46  ? 47.24300  -44.87900 -4.60800  1.000 53.88000  ? 46  LYS A HG2  1 
ATOM   671  H  HG3  . LYS A 1 46  ? 47.80400  -45.75800 -5.80600  1.000 53.88000  ? 46  LYS A HG3  1 
ATOM   672  H  HD2  . LYS A 1 46  ? 49.83400  -45.92600 -4.40600  1.000 57.76000  ? 46  LYS A HD2  1 
ATOM   673  H  HD3  . LYS A 1 46  ? 48.85500  -45.53000 -3.21900  1.000 57.76000  ? 46  LYS A HD3  1 
ATOM   674  H  HE2  . LYS A 1 46  ? 48.60900  -47.86000 -4.78800  1.000 65.76000  ? 46  LYS A HE2  1 
ATOM   675  H  HE3  . LYS A 1 46  ? 49.11100  -47.83000 -3.28000  1.000 65.76000  ? 46  LYS A HE3  1 
ATOM   676  H  HZ1  . LYS A 1 46  ? 46.54100  -47.29500 -4.04600  1.000 76.34000  ? 46  LYS A HZ1  1 
ATOM   677  H  HZ2  . LYS A 1 46  ? 46.95500  -48.50600 -3.36900  1.000 76.34000  ? 46  LYS A HZ2  1 
ATOM   678  H  HZ3  . LYS A 1 46  ? 46.99400  -47.23700 -2.67100  1.000 76.34000  ? 46  LYS A HZ3  1 
ATOM   679  N  N    . PRO A 1 47  ? 48.60700  -40.72200 -5.69500  1.000 44.43427  ? 47  PRO A N    1 
ATOM   680  C  CA   . PRO A 1 47  ? 49.27500  -39.42900 -5.89600  1.000 44.81590  ? 47  PRO A CA   1 
ATOM   681  C  C    . PRO A 1 47  ? 50.75800  -39.56800 -6.21200  1.000 47.61887  ? 47  PRO A C    1 
ATOM   682  O  O    . PRO A 1 47  ? 51.48400  -40.30100 -5.54000  1.000 51.05875  ? 47  PRO A O    1 
ATOM   683  C  CB   . PRO A 1 47  ? 49.06000  -38.72200 -4.55000  1.000 44.76589  ? 47  PRO A CB   1 
ATOM   684  C  CG   . PRO A 1 47  ? 47.72700  -39.22500 -4.10800  1.000 40.96281  ? 47  PRO A CG   1 
ATOM   685  C  CD   . PRO A 1 47  ? 47.73900  -40.70400 -4.50100  1.000 41.91818  ? 47  PRO A CD   1 
ATOM   686  H  HA   . PRO A 1 47  ? 48.84400  -38.94400 -6.61700  1.000 53.78000  ? 47  PRO A HA   1 
ATOM   687  H  HB2  . PRO A 1 47  ? 49.75800  -38.97100 -3.92300  1.000 53.72000  ? 47  PRO A HB2  1 
ATOM   688  H  HB3  . PRO A 1 47  ? 49.05200  -37.76000 -4.67200  1.000 53.72000  ? 47  PRO A HB3  1 
ATOM   689  H  HG2  . PRO A 1 47  ? 47.63100  -39.11900 -3.14800  1.000 49.16000  ? 47  PRO A HG2  1 
ATOM   690  H  HG3  . PRO A 1 47  ? 47.02000  -38.74600 -4.56700  1.000 49.16000  ? 47  PRO A HG3  1 
ATOM   691  H  HD2  . PRO A 1 47  ? 48.11400  -41.24800 -3.79200  1.000 50.30000  ? 47  PRO A HD2  1 
ATOM   692  H  HD3  . PRO A 1 47  ? 46.84500  -41.01100 -4.71800  1.000 50.30000  ? 47  PRO A HD3  1 
ATOM   693  N  N    . HIS A 1 48  ? 51.20300  -38.85200 -7.24500  1.000 52.53788  ? 48  HIS A N    1 
ATOM   694  C  CA   . HIS A 1 48  ? 52.62200  -38.65800 -7.50800  1.000 55.27242  ? 48  HIS A CA   1 
ATOM   695  C  C    . HIS A 1 48  ? 53.12200  -37.34500 -6.90400  1.000 50.34814  ? 48  HIS A C    1 
ATOM   696  O  O    . HIS A 1 48  ? 52.37000  -36.38600 -6.71700  1.000 46.93457  ? 48  HIS A O    1 
ATOM   697  C  CB   . HIS A 1 48  ? 52.95700  -38.63800 -9.00800  1.000 52.06677  ? 48  HIS A CB   1 
ATOM   698  C  CG   . HIS A 1 48  ? 52.40400  -39.78100 -9.79400  1.000 57.90694  ? 48  HIS A CG   1 
ATOM   699  N  ND1  . HIS A 1 48  ? 51.93600  -40.93700 -9.20700  1.000 63.99715  ? 48  HIS A ND1  1 
ATOM   700  C  CD2  . HIS A 1 48  ? 52.31600  -39.97700 -11.13100 1.000 66.65273  ? 48  HIS A CD2  1 
ATOM   701  C  CE1  . HIS A 1 48  ? 51.54800  -41.78100 -10.14700 1.000 66.89223  ? 48  HIS A CE1  1 
ATOM   702  N  NE2  . HIS A 1 48  ? 51.76600  -41.22100 -11.32400 1.000 76.20914  ? 48  HIS A NE2  1 
ATOM   703  H  H    . HIS A 1 48  ? 50.69100  -38.46300 -7.81600  1.000 63.04000  ? 48  HIS A H    1 
ATOM   704  H  HA   . HIS A 1 48  ? 53.08000  -39.41100 -7.10300  1.000 66.33000  ? 48  HIS A HA   1 
ATOM   705  H  HB2  . HIS A 1 48  ? 52.60000  -37.82200 -9.39200  1.000 62.48000  ? 48  HIS A HB2  1 
ATOM   706  H  HB3  . HIS A 1 48  ? 53.92200  -38.65700 -9.10700  1.000 62.48000  ? 48  HIS A HB3  1 
ATOM   707  H  HD2  . HIS A 1 48  ? 52.57900  -39.38000 -11.79400 1.000 79.98000  ? 48  HIS A HD2  1 
ATOM   708  H  HE1  . HIS A 1 48  ? 51.18400  -42.62500 -10.00500 1.000 80.27000  ? 48  HIS A HE1  1 
ATOM   709  H  HE2  . HIS A 1 48  ? 51.59200  -41.57800 -12.08700 1.000 91.45000  ? 48  HIS A HE2  1 
ATOM   710  N  N    . ASN A 1 49  ? 54.43000  -37.30500 -6.64100  1.000 48.03471  ? 49  ASN A N    1 
ATOM   711  C  CA   . ASN A 1 49  ? 55.08500  -36.07500 -6.20700  1.000 49.61911  ? 49  ASN A CA   1 
ATOM   712  C  C    . ASN A 1 49  ? 54.77900  -34.91100 -7.13700  1.000 46.65033  ? 49  ASN A C    1 
ATOM   713  O  O    . ASN A 1 49  ? 54.51300  -33.79200 -6.68400  1.000 45.48966  ? 49  ASN A O    1 
ATOM   714  C  CB   . ASN A 1 49  ? 56.59500  -36.30600 -6.15700  1.000 57.18054  ? 49  ASN A CB   1 
ATOM   715  C  CG   . ASN A 1 49  ? 57.00700  -37.20800 -5.03400  1.000 62.47854  ? 49  ASN A CG   1 
ATOM   716  O  OD1  . ASN A 1 49  ? 56.32900  -37.29300 -4.01200  1.000 68.85036  ? 49  ASN A OD1  1 
ATOM   717  N  ND2  . ASN A 1 49  ? 58.11000  -37.92500 -5.22900  1.000 71.36645  ? 49  ASN A ND2  1 
ATOM   718  H  H    . ASN A 1 49  ? 54.96000  -37.97900 -6.70600  1.000 57.64000  ? 49  ASN A H    1 
ATOM   719  H  HA   . ASN A 1 49  ? 54.75800  -35.84600 -5.32200  1.000 59.54000  ? 49  ASN A HA   1 
ATOM   720  H  HB2  . ASN A 1 49  ? 56.87900  -36.71400 -6.99000  1.000 68.62000  ? 49  ASN A HB2  1 
ATOM   721  H  HB3  . ASN A 1 49  ? 57.04100  -35.45300 -6.03600  1.000 68.62000  ? 49  ASN A HB3  1 
ATOM   722  H  HD21 . ASN A 1 49  ? 58.54300  -37.85400 -5.96800  1.000 85.64000  ? 49  ASN A HD21 1 
ATOM   723  H  HD22 . ASN A 1 49  ? 58.39000  -38.45800 -4.61600  1.000 85.64000  ? 49  ASN A HD22 1 
ATOM   724  N  N    . SER A 1 50  ? 54.85000  -35.15100 -8.44800  1.000 45.23174  ? 50  SER A N    1 
ATOM   725  C  CA   . SER A 1 50  ? 54.62600  -34.09800 -9.42900  1.000 42.04451  ? 50  SER A CA   1 
ATOM   726  C  C    . SER A 1 50  ? 53.22100  -33.51700 -9.36200  1.000 44.91328  ? 50  SER A C    1 
ATOM   727  O  O    . SER A 1 50  ? 52.97500  -32.45800 -9.95100  1.000 44.38953  ? 50  SER A O    1 
ATOM   728  C  CB   . SER A 1 50  ? 54.88200  -34.64800 -10.83400 1.000 43.68945  ? 50  SER A CB   1 
ATOM   729  O  OG   . SER A 1 50  ? 53.85100  -35.54600 -11.22200 1.000 47.12670  ? 50  SER A OG   1 
ATOM   730  H  H    . SER A 1 50  ? 55.02800  -35.91800 -8.79200  1.000 54.28000  ? 50  SER A H    1 
ATOM   731  H  HA   . SER A 1 50  ? 55.25200  -33.37700 -9.25800  1.000 50.45000  ? 50  SER A HA   1 
ATOM   732  H  HB2  . SER A 1 50  ? 54.91000  -33.91000 -11.46200 1.000 52.43000  ? 50  SER A HB2  1 
ATOM   733  H  HB3  . SER A 1 50  ? 55.73000  -35.12000 -10.83900 1.000 52.43000  ? 50  SER A HB3  1 
ATOM   734  H  HG   . SER A 1 50  ? 54.01000  -35.85000 -11.98900 1.000 56.55000  ? 50  SER A HG   1 
ATOM   735  N  N    . HIS A 1 51  ? 52.29600  -34.18800 -8.68200  1.000 41.88660  ? 51  HIS A N    1 
ATOM   736  C  CA   . HIS A 1 51  ? 50.92900  -33.71100 -8.56500  1.000 39.74424  ? 51  HIS A CA   1 
ATOM   737  C  C    . HIS A 1 51  ? 50.77900  -32.59300 -7.54000  1.000 40.15481  ? 51  HIS A C    1 
ATOM   738  O  O    . HIS A 1 51  ? 49.71500  -31.96400 -7.49100  1.000 35.84377  ? 51  HIS A O    1 
ATOM   739  C  CB   . HIS A 1 51  ? 50.01300  -34.86800 -8.16800  1.000 39.79688  ? 51  HIS A CB   1 
ATOM   740  C  CG   . HIS A 1 51  ? 49.76700  -35.84900 -9.26500  1.000 39.22576  ? 51  HIS A CG   1 
ATOM   741  N  ND1  . HIS A 1 51  ? 49.16200  -37.06700 -9.04700  1.000 39.63107  ? 51  HIS A ND1  1 
ATOM   742  C  CD2  . HIS A 1 51  ? 50.03300  -35.79000 -10.59300 1.000 42.01293  ? 51  HIS A CD2  1 
ATOM   743  C  CE1  . HIS A 1 51  ? 49.07100  -37.72200 -10.19100 1.000 44.61851  ? 51  HIS A CE1  1 
ATOM   744  N  NE2  . HIS A 1 51  ? 49.58700  -36.96700 -11.14700 1.000 42.74197  ? 51  HIS A NE2  1 
ATOM   745  H  H    . HIS A 1 51  ? 52.44000  -34.93200 -8.27500  1.000 50.27000  ? 51  HIS A H    1 
ATOM   746  H  HA   . HIS A 1 51  ? 50.64500  -33.37100 -9.42800  1.000 47.69000  ? 51  HIS A HA   1 
ATOM   747  H  HB2  . HIS A 1 51  ? 50.42000  -35.34700 -7.42900  1.000 47.76000  ? 51  HIS A HB2  1 
ATOM   748  H  HB3  . HIS A 1 51  ? 49.15500  -34.50600 -7.89700  1.000 47.76000  ? 51  HIS A HB3  1 
ATOM   749  H  HD2  . HIS A 1 51  ? 50.44100  -35.08700 -11.04400 1.000 50.42000  ? 51  HIS A HD2  1 
ATOM   750  H  HE1  . HIS A 1 51  ? 48.70700  -38.56900 -10.30500 1.000 53.54000  ? 51  HIS A HE1  1 
ATOM   751  H  HE2  . HIS A 1 51  ? 49.63500  -37.17700 -11.97900 1.000 51.29000  ? 51  HIS A HE2  1 
ATOM   752  N  N    . GLU A 1 52  ? 51.79900  -32.34700 -6.71200  1.000 38.81518  ? 52  GLU A N    1 
ATOM   753  C  CA   . GLU A 1 52  ? 51.66800  -31.35900 -5.65000  1.000 41.50761  ? 52  GLU A CA   1 
ATOM   754  C  C    . GLU A 1 52  ? 51.30400  -30.00100 -6.23400  1.000 38.89414  ? 52  GLU A C    1 
ATOM   755  O  O    . GLU A 1 52  ? 51.94200  -29.51500 -7.17200  1.000 37.19920  ? 52  GLU A O    1 
ATOM   756  C  CB   . GLU A 1 52  ? 52.96300  -31.25500 -4.84400  1.000 43.42626  ? 52  GLU A CB   1 
ATOM   757  C  CG   . GLU A 1 52  ? 52.89100  -30.25300 -3.68400  1.000 46.10290  ? 52  GLU A CG   1 
ATOM   758  C  CD   . GLU A 1 52  ? 53.41700  -30.82600 -2.38100  1.000 55.87512  ? 52  GLU A CD   1 
ATOM   759  O  OE1  . GLU A 1 52  ? 54.58500  -31.28000 -2.35200  1.000 59.27290  ? 52  GLU A OE1  1 
ATOM   760  O  OE2  . GLU A 1 52  ? 52.66700  -30.82100 -1.37800  1.000 59.20973  ? 52  GLU A OE2  1 
ATOM   761  H  H    . GLU A 1 52  ? 52.56500  -32.73500 -6.74700  1.000 46.58000  ? 52  GLU A H    1 
ATOM   762  H  HA   . GLU A 1 52  ? 50.96200  -31.63900 -5.04600  1.000 49.81000  ? 52  GLU A HA   1 
ATOM   763  H  HB2  . GLU A 1 52  ? 53.16800  -32.12600 -4.47000  1.000 52.11000  ? 52  GLU A HB2  1 
ATOM   764  H  HB3  . GLU A 1 52  ? 53.67700  -30.97200 -5.43600  1.000 52.11000  ? 52  GLU A HB3  1 
ATOM   765  H  HG2  . GLU A 1 52  ? 53.42400  -29.47300 -3.90600  1.000 55.32000  ? 52  GLU A HG2  1 
ATOM   766  H  HG3  . GLU A 1 52  ? 51.96600  -29.99400 -3.54600  1.000 55.32000  ? 52  GLU A HG3  1 
ATOM   767  N  N    . GLY A 1 53  ? 50.26600  -29.39500 -5.67100  1.000 37.70189  ? 53  GLY A N    1 
ATOM   768  C  CA   . GLY A 1 53  ? 49.82600  -28.08500 -6.07000  1.000 37.74137  ? 53  GLY A CA   1 
ATOM   769  C  C    . GLY A 1 53  ? 48.93100  -28.05600 -7.27800  1.000 32.99343  ? 53  GLY A C    1 
ATOM   770  O  O    . GLY A 1 53  ? 48.50300  -26.97000 -7.67800  1.000 37.19393  ? 53  GLY A O    1 
ATOM   771  H  H    . GLY A 1 53  ? 49.79300  -29.73800 -5.04000  1.000 45.24000  ? 53  GLY A H    1 
ATOM   772  H  HA2  . GLY A 1 53  ? 49.34000  -27.68300 -5.33300  1.000 45.29000  ? 53  GLY A HA2  1 
ATOM   773  H  HA3  . GLY A 1 53  ? 50.60500  -27.54300 -6.26700  1.000 45.29000  ? 53  GLY A HA3  1 
ATOM   774  N  N    . LYS A 1 54  ? 48.63000  -29.20400 -7.87100  1.000 33.87775  ? 54  LYS A N    1 
ATOM   775  C  CA   . LYS A 1 54  ? 47.84400  -29.24100 -9.08700  1.000 34.91471  ? 54  LYS A CA   1 
ATOM   776  C  C    . LYS A 1 54  ? 46.36300  -29.29700 -8.74500  1.000 35.34634  ? 54  LYS A C    1 
ATOM   777  O  O    . LYS A 1 54  ? 45.96100  -29.67000 -7.63800  1.000 33.13029  ? 54  LYS A O    1 
ATOM   778  C  CB   . LYS A 1 54  ? 48.23700  -30.44400 -9.94300  1.000 36.14118  ? 54  LYS A CB   1 
ATOM   779  C  CG   . LYS A 1 54  ? 49.59900  -30.27200 -10.58300 1.000 41.73395  ? 54  LYS A CG   1 
ATOM   780  C  CD   . LYS A 1 54  ? 49.74800  -31.10900 -11.84100 1.000 46.41872  ? 54  LYS A CD   1 
ATOM   781  C  CE   . LYS A 1 54  ? 51.06000  -30.78500 -12.53300 1.000 48.99535  ? 54  LYS A CE   1 
ATOM   782  N  NZ   . LYS A 1 54  ? 51.39100  -31.82200 -13.53800 1.000 76.46969  ? 54  LYS A NZ   1 
ATOM   783  H  H    . LYS A 1 54  ? 48.87200  -29.97800 -7.58400  1.000 40.65000  ? 54  LYS A H    1 
ATOM   784  H  HA   . LYS A 1 54  ? 48.00900  -28.44100 -9.60900  1.000 41.90000  ? 54  LYS A HA   1 
ATOM   785  H  HB2  . LYS A 1 54  ? 48.26300  -31.23700 -9.38400  1.000 43.37000  ? 54  LYS A HB2  1 
ATOM   786  H  HB3  . LYS A 1 54  ? 47.58200  -30.55900 -10.65000 1.000 43.37000  ? 54  LYS A HB3  1 
ATOM   787  H  HG2  . LYS A 1 54  ? 49.72300  -29.34000 -10.82400 1.000 50.08000  ? 54  LYS A HG2  1 
ATOM   788  H  HG3  . LYS A 1 54  ? 50.28500  -30.54600 -9.95400  1.000 50.08000  ? 54  LYS A HG3  1 
ATOM   789  H  HD2  . LYS A 1 54  ? 49.74400  -32.05100 -11.60800 1.000 55.71000  ? 54  LYS A HD2  1 
ATOM   790  H  HD3  . LYS A 1 54  ? 49.01900  -30.91500 -12.45100 1.000 55.71000  ? 54  LYS A HD3  1 
ATOM   791  H  HE2  . LYS A 1 54  ? 50.98600  -29.93000 -12.98500 1.000 58.79000  ? 54  LYS A HE2  1 
ATOM   792  H  HE3  . LYS A 1 54  ? 51.77400  -30.75300 -11.87700 1.000 58.79000  ? 54  LYS A HE3  1 
ATOM   793  H  HZ1  . LYS A 1 54  ? 52.16100  -31.62500 -13.93700 1.000 91.77000  ? 54  LYS A HZ1  1 
ATOM   794  H  HZ2  . LYS A 1 54  ? 51.46500  -32.61600 -13.14300 1.000 91.77000  ? 54  LYS A HZ2  1 
ATOM   795  H  HZ3  . LYS A 1 54  ? 50.74900  -31.86500 -14.15300 1.000 91.77000  ? 54  LYS A HZ3  1 
ATOM   796  N  N    . THR A 1 55  ? 45.55500  -28.90200 -9.71800  1.000 32.54601  ? 55  THR A N    1 
ATOM   797  C  CA   . THR A 1 55  ? 44.11000  -28.87500 -9.58400  1.000 32.61180  ? 55  THR A CA   1 
ATOM   798  C  C    . THR A 1 55  ? 43.49800  -30.09500 -10.24500 1.000 32.59075  ? 55  THR A C    1 
ATOM   799  O  O    . THR A 1 55  ? 43.77200  -30.38300 -11.42100 1.000 32.43020  ? 55  THR A O    1 
ATOM   800  C  CB   . THR A 1 55  ? 43.53300  -27.60200 -10.19900 1.000 31.24059  ? 55  THR A CB   1 
ATOM   801  O  OG1  . THR A 1 55  ? 44.04700  -26.46300 -9.50400  1.000 33.80932  ? 55  THR A OG1  1 
ATOM   802  C  CG2  . THR A 1 55  ? 42.03100  -27.61900 -10.11500 1.000 33.43032  ? 55  THR A CG2  1 
ATOM   803  H  H    . THR A 1 55  ? 45.83000  -28.63800 -10.48900 1.000 39.05000  ? 55  THR A H    1 
ATOM   804  H  HA   . THR A 1 55  ? 43.88000  -28.89700 -8.64200  1.000 39.14000  ? 55  THR A HA   1 
ATOM   805  H  HB   . THR A 1 55  ? 43.78200  -27.54200 -11.13400 1.000 37.49000  ? 55  THR A HB   1 
ATOM   806  H  HG1  . THR A 1 55  ? 43.72200  -25.75800 -9.82700  1.000 40.57000  ? 55  THR A HG1  1 
ATOM   807  H  HG21 . THR A 1 55  ? 41.68300  -26.71900 -10.21000 1.000 40.11000  ? 55  THR A HG21 1 
ATOM   808  H  HG22 . THR A 1 55  ? 41.66500  -28.17500 -10.82100 1.000 40.11000  ? 55  THR A HG22 1 
ATOM   809  H  HG23 . THR A 1 55  ? 41.75000  -27.97600 -9.25700  1.000 40.11000  ? 55  THR A HG23 1 
ATOM   810  N  N    . PHE A 1 56  ? 42.63900  -30.77700 -9.49700  1.000 29.74830  ? 56  PHE A N    1 
ATOM   811  C  CA   . PHE A 1 56  ? 41.91800  -31.95400 -9.95500  1.000 32.19597  ? 56  PHE A CA   1 
ATOM   812  C  C    . PHE A 1 56  ? 40.43100  -31.66000 -9.94500  1.000 31.75118  ? 56  PHE A C    1 
ATOM   813  O  O    . PHE A 1 56  ? 39.91100  -31.05500 -8.99900  1.000 29.59565  ? 56  PHE A O    1 
ATOM   814  C  CB   . PHE A 1 56  ? 42.21100  -33.15100 -9.03300  1.000 31.56168  ? 56  PHE A CB   1 
ATOM   815  C  CG   . PHE A 1 56  ? 43.63000  -33.59200 -9.08000  1.000 33.20924  ? 56  PHE A CG   1 
ATOM   816  C  CD1  . PHE A 1 56  ? 44.61300  -32.90900 -8.38100  1.000 30.42470  ? 56  PHE A CD1  1 
ATOM   817  C  CD2  . PHE A 1 56  ? 43.99700  -34.66000 -9.86500  1.000 33.30926  ? 56  PHE A CD2  1 
ATOM   818  C  CE1  . PHE A 1 56  ? 45.93100  -33.30000 -8.46300  1.000 32.00121  ? 56  PHE A CE1  1 
ATOM   819  C  CE2  . PHE A 1 56  ? 45.31900  -35.06400 -9.92600  1.000 35.15158  ? 56  PHE A CE2  1 
ATOM   820  C  CZ   . PHE A 1 56  ? 46.27900  -34.38300 -9.23400  1.000 35.81482  ? 56  PHE A CZ   1 
ATOM   821  H  H    . PHE A 1 56  ? 42.45100  -30.56700 -8.68500  1.000 35.70000  ? 56  PHE A H    1 
ATOM   822  H  HA   . PHE A 1 56  ? 42.18400  -32.18200 -10.86000 1.000 38.63000  ? 56  PHE A HA   1 
ATOM   823  H  HB2  . PHE A 1 56  ? 42.00700  -32.90000 -8.11900  1.000 37.87000  ? 56  PHE A HB2  1 
ATOM   824  H  HB3  . PHE A 1 56  ? 41.65700  -33.89900 -9.30400  1.000 37.87000  ? 56  PHE A HB3  1 
ATOM   825  H  HD1  . PHE A 1 56  ? 44.38100  -32.18000 -7.85200  1.000 36.51000  ? 56  PHE A HD1  1 
ATOM   826  H  HD2  . PHE A 1 56  ? 43.35200  -35.11400 -10.35800 1.000 39.97000  ? 56  PHE A HD2  1 
ATOM   827  H  HE1  . PHE A 1 56  ? 46.58500  -32.83200 -7.99600  1.000 38.40000  ? 56  PHE A HE1  1 
ATOM   828  H  HE2  . PHE A 1 56  ? 45.55400  -35.80200 -10.44100 1.000 42.18000  ? 56  PHE A HE2  1 
ATOM   829  H  HZ   . PHE A 1 56  ? 47.16700  -34.65300 -9.28300  1.000 42.97000  ? 56  PHE A HZ   1 
ATOM   830  N  N    . TYR A 1 57  ? 39.74200  -32.09600 -10.97500 1.000 29.92201  ? 57  TYR A N    1 
ATOM   831  C  CA   . TYR A 1 57  ? 38.28900  -32.06300 -10.95200 1.000 28.26128  ? 57  TYR A CA   1 
ATOM   832  C  C    . TYR A 1 57  ? 37.76500  -33.27200 -10.19600 1.000 30.56419  ? 57  TYR A C    1 
ATOM   833  O  O    . TYR A 1 57  ? 38.30600  -34.37900 -10.30600 1.000 32.19070  ? 57  TYR A O    1 
ATOM   834  C  CB   . TYR A 1 57  ? 37.71600  -32.10700 -12.35900 1.000 27.62963  ? 57  TYR A CB   1 
ATOM   835  C  CG   . TYR A 1 57  ? 37.66900  -30.80600 -13.09400 1.000 28.58237  ? 57  TYR A CG   1 
ATOM   836  C  CD1  . TYR A 1 57  ? 38.81400  -30.28200 -13.67200 1.000 33.21977  ? 57  TYR A CD1  1 
ATOM   837  C  CD2  . TYR A 1 57  ? 36.46900  -30.15000 -13.29400 1.000 29.14034  ? 57  TYR A CD2  1 
ATOM   838  C  CE1  . TYR A 1 57  ? 38.77100  -29.12400 -14.38800 1.000 33.99881  ? 57  TYR A CE1  1 
ATOM   839  C  CE2  . TYR A 1 57  ? 36.41300  -28.99100 -14.03100 1.000 31.81434  ? 57  TYR A CE2  1 
ATOM   840  C  CZ   . TYR A 1 57  ? 37.57200  -28.48400 -14.57300 1.000 32.21702  ? 57  TYR A CZ   1 
ATOM   841  O  OH   . TYR A 1 57  ? 37.55700  -27.32500 -15.31800 1.000 34.76733  ? 57  TYR A OH   1 
ATOM   842  H  H    . TYR A 1 57  ? 40.08500  -32.41500 -11.69700 1.000 35.90000  ? 57  TYR A H    1 
ATOM   843  H  HA   . TYR A 1 57  ? 38.00300  -31.24100 -10.52400 1.000 33.91000  ? 57  TYR A HA   1 
ATOM   844  H  HB2  . TYR A 1 57  ? 38.25800  -32.71400 -12.88800 1.000 33.16000  ? 57  TYR A HB2  1 
ATOM   845  H  HB3  . TYR A 1 57  ? 36.80600  -32.43800 -12.30500 1.000 33.16000  ? 57  TYR A HB3  1 
ATOM   846  H  HD1  . TYR A 1 57  ? 39.62400  -30.72700 -13.56900 1.000 39.86000  ? 57  TYR A HD1  1 
ATOM   847  H  HD2  . TYR A 1 57  ? 35.69000  -30.49700 -12.92400 1.000 34.96000  ? 57  TYR A HD2  1 
ATOM   848  H  HE1  . TYR A 1 57  ? 39.55000  -28.77000 -14.75100 1.000 40.80000  ? 57  TYR A HE1  1 
ATOM   849  H  HE2  . TYR A 1 57  ? 35.60200  -28.55600 -14.16200 1.000 38.18000  ? 57  TYR A HE2  1 
ATOM   850  H  HH   . TYR A 1 57  ? 36.76600  -27.06500 -15.42900 1.000 41.72000  ? 57  TYR A HH   1 
ATOM   851  N  N    . VAL A 1 58  ? 36.69200  -33.05800 -9.44300  1.000 30.54840  ? 58  VAL A N    1 
ATOM   852  C  CA   . VAL A 1 58  ? 35.97500  -34.11800 -8.76200  1.000 31.22743  ? 58  VAL A CA   1 
ATOM   853  C  C    . VAL A 1 58  ? 34.50000  -33.95700 -9.08500  1.000 32.82762  ? 58  VAL A C    1 
ATOM   854  O  O    . VAL A 1 58  ? 34.08100  -32.97500 -9.69400  1.000 33.18819  ? 58  VAL A O    1 
ATOM   855  C  CB   . VAL A 1 58  ? 36.20500  -34.08600 -7.23900  1.000 29.39826  ? 58  VAL A CB   1 
ATOM   856  C  CG1  . VAL A 1 58  ? 37.63800  -34.44100 -6.92200  1.000 32.77498  ? 58  VAL A CG1  1 
ATOM   857  C  CG2  . VAL A 1 58  ? 35.84000  -32.71700 -6.68500  1.000 32.69866  ? 58  VAL A CG2  1 
ATOM   858  H  H    . VAL A 1 58  ? 36.35200  -32.27900 -9.30900  1.000 36.66000  ? 58  VAL A H    1 
ATOM   859  H  HA   . VAL A 1 58  ? 36.27300  -34.98100 -9.09100  1.000 37.48000  ? 58  VAL A HA   1 
ATOM   860  H  HB   . VAL A 1 58  ? 35.63500  -34.74300 -6.81000  1.000 35.28000  ? 58  VAL A HB   1 
ATOM   861  H  HG11 . VAL A 1 58  ? 37.76000  -34.43100 -5.96000  1.000 39.33000  ? 58  VAL A HG11 1 
ATOM   862  H  HG12 . VAL A 1 58  ? 37.83000  -35.32500 -7.27100  1.000 39.33000  ? 58  VAL A HG12 1 
ATOM   863  H  HG13 . VAL A 1 58  ? 38.22400  -33.78800 -7.33600  1.000 39.33000  ? 58  VAL A HG13 1 
ATOM   864  H  HG21 . VAL A 1 58  ? 36.01900  -32.70500 -5.73200  1.000 39.24000  ? 58  VAL A HG21 1 
ATOM   865  H  HG22 . VAL A 1 58  ? 36.37600  -32.04300 -7.13100  1.000 39.24000  ? 58  VAL A HG22 1 
ATOM   866  H  HG23 . VAL A 1 58  ? 34.89800  -32.55200 -6.84700  1.000 39.24000  ? 58  VAL A HG23 1 
ATOM   867  N  N    . LEU A 1 59  ? 33.70200  -34.91400 -8.65300  1.000 31.58273  ? 59  LEU A N    1 
ATOM   868  C  CA   . LEU A 1 59  ? 32.26300  -34.75400 -8.82700  1.000 32.41441  ? 59  LEU A CA   1 
ATOM   869  C  C    . LEU A 1 59  ? 31.72500  -33.86800 -7.71100  1.000 33.76194  ? 59  LEU A C    1 
ATOM   870  O  O    . LEU A 1 59  ? 32.33200  -33.76000 -6.64600  1.000 35.07263  ? 59  LEU A O    1 
ATOM   871  C  CB   . LEU A 1 59  ? 31.55900  -36.10200 -8.83600  1.000 33.48823  ? 59  LEU A CB   1 
ATOM   872  C  CG   . LEU A 1 59  ? 31.99900  -37.09600 -9.90200  1.000 32.50916  ? 59  LEU A CG   1 
ATOM   873  C  CD1  . LEU A 1 59  ? 31.18800  -38.37200 -9.77200  1.000 36.88863  ? 59  LEU A CD1  1 
ATOM   874  C  CD2  . LEU A 1 59  ? 31.87700  -36.51600 -11.31100 1.000 32.74340  ? 59  LEU A CD2  1 
ATOM   875  H  H    . LEU A 1 59  ? 33.95500  -35.64000 -8.26800  1.000 37.90000  ? 59  LEU A H    1 
ATOM   876  H  HA   . LEU A 1 59  ? 32.07200  -34.34100 -9.68400  1.000 38.90000  ? 59  LEU A HA   1 
ATOM   877  H  HB2  . LEU A 1 59  ? 31.70800  -36.52400 -7.97500  1.000 40.19000  ? 59  LEU A HB2  1 
ATOM   878  H  HB3  . LEU A 1 59  ? 30.61100  -35.94400 -8.96800  1.000 40.19000  ? 59  LEU A HB3  1 
ATOM   879  H  HG   . LEU A 1 59  ? 32.93700  -37.30000 -9.76900  1.000 39.01000  ? 59  LEU A HG   1 
ATOM   880  H  HD11 . LEU A 1 59  ? 31.47900  -39.00100 -10.45100 1.000 44.27000  ? 59  LEU A HD11 1 
ATOM   881  H  HD12 . LEU A 1 59  ? 31.33100  -38.74800 -8.88900  1.000 44.27000  ? 59  LEU A HD12 1 
ATOM   882  H  HD13 . LEU A 1 59  ? 30.24900  -38.16300 -9.89500  1.000 44.27000  ? 59  LEU A HD13 1 
ATOM   883  H  HD21 . LEU A 1 59  ? 32.07900  -37.21000 -11.95700 1.000 39.29000  ? 59  LEU A HD21 1 
ATOM   884  H  HD22 . LEU A 1 59  ? 30.97100  -36.19500 -11.44400 1.000 39.29000  ? 59  LEU A HD22 1 
ATOM   885  H  HD23 . LEU A 1 59  ? 32.50500  -35.78200 -11.40600 1.000 39.29000  ? 59  LEU A HD23 1 
ATOM   886  N  N    . PRO A 1 60  ? 30.58700  -33.16100 -7.91300  1.000 33.57771  ? 60  PRO A N    1 
ATOM   887  C  CA   . PRO A 1 60  ? 30.06100  -32.22800 -6.91100  1.000 34.16725  ? 60  PRO A CA   1 
ATOM   888  C  C    . PRO A 1 60  ? 29.38500  -33.02600 -5.79300  1.000 36.51490  ? 60  PRO A C    1 
ATOM   889  O  O    . PRO A 1 60  ? 28.21400  -32.87000 -5.62000  1.000 41.88660  ? 60  PRO A O    1 
ATOM   890  C  CB   . PRO A 1 60  ? 29.12600  -31.31000 -7.72400  1.000 33.04080  ? 60  PRO A CB   1 
ATOM   891  C  CG   . PRO A 1 60  ? 29.39900  -31.65400 -9.16200  1.000 38.15984  ? 60  PRO A CG   1 
ATOM   892  C  CD   . PRO A 1 60  ? 29.75700  -33.11800 -9.11700  1.000 35.49899  ? 60  PRO A CD   1 
ATOM   893  H  HA   . PRO A 1 60  ? 30.80500  -31.69000 -6.54200  1.000 41.00000  ? 60  PRO A HA   1 
ATOM   894  H  HB2  . PRO A 1 60  ? 28.18500  -31.46200 -7.51400  1.000 39.65000  ? 60  PRO A HB2  1 
ATOM   895  H  HB3  . PRO A 1 60  ? 29.33500  -30.36800 -7.55300  1.000 39.65000  ? 60  PRO A HB3  1 
ATOM   896  H  HG2  . PRO A 1 60  ? 28.60700  -31.50200 -9.71700  1.000 45.79000  ? 60  PRO A HG2  1 
ATOM   897  H  HG3  . PRO A 1 60  ? 30.14300  -31.12300 -9.51400  1.000 45.79000  ? 60  PRO A HG3  1 
ATOM   898  H  HD2  . PRO A 1 60  ? 28.96500  -33.67800 -9.02200  1.000 42.60000  ? 60  PRO A HD2  1 
ATOM   899  H  HD3  . PRO A 1 60  ? 30.25200  -33.38500 -9.91200  1.000 42.60000  ? 60  PRO A HD3  1 
ATOM   900  N  N    . ASN A 1 61  ? 30.14800  -33.77400 -5.00600  1.000 41.28653  ? 61  ASN A N    1 
ATOM   901  C  CA   . ASN A 1 61  ? 29.59200  -34.71100 -3.99500  1.000 46.92142  ? 61  ASN A CA   1 
ATOM   902  C  C    . ASN A 1 61  ? 29.68100  -34.12900 -2.58000  1.000 43.61576  ? 61  ASN A C    1 
ATOM   903  O  O    . ASN A 1 61  ? 29.84400  -34.91800 -1.64800  1.000 44.22899  ? 61  ASN A O    1 
ATOM   904  C  CB   . ASN A 1 61  ? 30.23500  -36.09100 -4.16300  1.000 52.34312  ? 61  ASN A CB   1 
ATOM   905  C  CG   . ASN A 1 61  ? 29.88900  -36.75400 -5.48100  1.000 58.12539  ? 61  ASN A CG   1 
ATOM   906  O  OD1  . ASN A 1 61  ? 28.95400  -36.35400 -6.17100  1.000 56.87524  ? 61  ASN A OD1  1 
ATOM   907  N  ND2  . ASN A 1 61  ? 30.64000  -37.78100 -5.84100  1.000 45.20279  ? 61  ASN A ND2  1 
ATOM   908  H  H    . ASN A 1 61  ? 31.05600  -33.73500 -5.01300  1.000 49.54000  ? 61  ASN A H    1 
ATOM   909  H  HA   . ASN A 1 61  ? 28.63800  -34.82700 -4.19200  1.000 56.31000  ? 61  ASN A HA   1 
ATOM   910  H  HB2  . ASN A 1 61  ? 31.20300  -35.99800 -4.09900  1.000 62.81000  ? 61  ASN A HB2  1 
ATOM   911  H  HB3  . ASN A 1 61  ? 29.93900  -36.67200 -3.43500  1.000 62.81000  ? 61  ASN A HB3  1 
ATOM   912  H  HD21 . ASN A 1 61  ? 31.18000  -38.15900 -5.25400  1.000 54.24000  ? 61  ASN A HD21 1 
ATOM   913  H  HD22 . ASN A 1 61  ? 30.61100  -38.08000 -6.67300  1.000 54.24000  ? 61  ASN A HD22 1 
ATOM   914  N  N    . ASP A 1 62  ? 29.63300  -32.81000 -2.42000  1.000 41.98924  ? 62  ASP A N    1 
ATOM   915  C  CA   . ASP A 1 62  ? 29.47400  -32.16100 -1.09100  1.000 39.90215  ? 62  ASP A CA   1 
ATOM   916  C  C    . ASP A 1 62  ? 28.60400  -30.93600 -1.37200  1.000 41.60236  ? 62  ASP A C    1 
ATOM   917  O  O    . ASP A 1 62  ? 28.47100  -30.62000 -2.52300  1.000 36.69387  ? 62  ASP A O    1 
ATOM   918  C  CB   . ASP A 1 62  ? 30.77900  -31.92000 -0.33700  1.000 44.43427  ? 62  ASP A CB   1 
ATOM   919  C  CG   . ASP A 1 62  ? 31.67900  -30.81600 -0.83900  1.000 47.61624  ? 62  ASP A CG   1 
ATOM   920  O  OD1  . ASP A 1 62  ? 31.27900  -29.66100 -0.75000  1.000 38.97046  ? 62  ASP A OD1  1 
ATOM   921  O  OD2  . ASP A 1 62  ? 32.80400  -31.13600 -1.23000  1.000 49.15853  ? 62  ASP A OD2  1 
ATOM   922  H  H    . ASP A 1 62  ? 29.71300  -32.22500 -3.11300  1.000 50.38000  ? 62  ASP A H    1 
ATOM   923  H  HA   . ASP A 1 62  ? 28.94000  -32.76900 -0.53200  1.000 47.88000  ? 62  ASP A HA   1 
ATOM   924  H  HB2  . ASP A 1 62  ? 30.55700  -31.71600 0.59400   1.000 53.32000  ? 62  ASP A HB2  1 
ATOM   925  H  HB3  . ASP A 1 62  ? 31.29600  -32.75100 -0.34800  1.000 53.32000  ? 62  ASP A HB3  1 
ATOM   926  N  N    . ASP A 1 63  ? 28.01000  -30.31000 -0.37000  1.000 34.94893  ? 63  ASP A N    1 
ATOM   927  C  CA   . ASP A 1 63  ? 27.03400  -29.24200 -0.58100  1.000 36.89653  ? 63  ASP A CA   1 
ATOM   928  C  C    . ASP A 1 63  ? 27.66400  -28.01400 -1.22900  1.000 35.19633  ? 63  ASP A C    1 
ATOM   929  O  O    . ASP A 1 63  ? 27.03900  -27.34100 -2.06700  1.000 34.83312  ? 63  ASP A O    1 
ATOM   930  C  CB   . ASP A 1 63  ? 26.38400  -28.80200 0.72800   1.000 34.80154  ? 63  ASP A CB   1 
ATOM   931  C  CG   . ASP A 1 63  ? 25.51300  -29.86300 1.35300   1.000 39.54158  ? 63  ASP A CG   1 
ATOM   932  O  OD1  . ASP A 1 63  ? 25.15700  -30.85200 0.69100   1.000 37.44660  ? 63  ASP A OD1  1 
ATOM   933  O  OD2  . ASP A 1 63  ? 25.15300  -29.68100 2.53300   1.000 43.38415  ? 63  ASP A OD2  1 
ATOM   934  H  H    . ASP A 1 63  ? 28.16100  -30.50900 0.45300   1.000 41.94000  ? 63  ASP A H    1 
ATOM   935  H  HA   . ASP A 1 63  ? 26.35100  -29.61000 -1.16300  1.000 44.28000  ? 63  ASP A HA   1 
ATOM   936  H  HB2  . ASP A 1 63  ? 27.08200  -28.57900 1.36400   1.000 41.76000  ? 63  ASP A HB2  1 
ATOM   937  H  HB3  . ASP A 1 63  ? 25.83000  -28.02500 0.55700   1.000 41.76000  ? 63  ASP A HB3  1 
ATOM   938  N  N    . THR A 1 64  ? 28.88600  -27.67800 -0.82000  1.000 34.07251  ? 64  THR A N    1 
ATOM   939  C  CA   . THR A 1 64  ? 29.57000  -26.52600 -1.40000  1.000 30.54577  ? 64  THR A CA   1 
ATOM   940  C  C    . THR A 1 64  ? 29.82200  -26.74100 -2.87500  1.000 31.77223  ? 64  THR A C    1 
ATOM   941  O  O    . THR A 1 64  ? 29.57700  -25.84700 -3.68800  1.000 31.61958  ? 64  THR A O    1 
ATOM   942  C  CB   . THR A 1 64  ? 30.88500  -26.27300 -0.66700  1.000 32.85131  ? 64  THR A CB   1 
ATOM   943  O  OG1  . THR A 1 64  ? 30.58600  -26.00500 0.69800   1.000 40.34694  ? 64  THR A OG1  1 
ATOM   944  C  CG2  . THR A 1 64  ? 31.60200  -25.10600 -1.27500  1.000 37.36501  ? 64  THR A CG2  1 
ATOM   945  H  H    . THR A 1 64  ? 29.33500  -28.09500 -0.21600  1.000 40.89000  ? 64  THR A H    1 
ATOM   946  H  HA   . THR A 1 64  ? 29.01000  -25.74200 -1.29300  1.000 36.65000  ? 64  THR A HA   1 
ATOM   947  H  HB   . THR A 1 64  ? 31.47000  -27.04400 -0.73200  1.000 39.42000  ? 64  THR A HB   1 
ATOM   948  H  HG1  . THR A 1 64  ? 31.29600  -25.87400 1.12700   1.000 48.42000  ? 64  THR A HG1  1 
ATOM   949  H  HG21 . THR A 1 64  ? 32.24800  -24.74900 -0.64500  1.000 44.84000  ? 64  THR A HG21 1 
ATOM   950  H  HG22 . THR A 1 64  ? 32.06600  -25.38400 -2.07900  1.000 44.84000  ? 64  THR A HG22 1 
ATOM   951  H  HG23 . THR A 1 64  ? 30.96700  -24.40900 -1.50300  1.000 44.84000  ? 64  THR A HG23 1 
ATOM   952  N  N    . LEU A 1 65  ? 30.31000  -27.93000 -3.23800  1.000 30.76421  ? 65  LEU A N    1 
ATOM   953  C  CA   . LEU A 1 65  ? 30.55700  -28.22200 -4.64200  1.000 31.27217  ? 65  LEU A CA   1 
ATOM   954  C  C    . LEU A 1 65  ? 29.26400  -28.25000 -5.44500  1.000 33.53823  ? 65  LEU A C    1 
ATOM   955  O  O    . LEU A 1 65  ? 29.25700  -27.86500 -6.61600  1.000 28.28760  ? 65  LEU A O    1 
ATOM   956  C  CB   . LEU A 1 65  ? 31.28600  -29.56100 -4.77600  1.000 34.14883  ? 65  LEU A CB   1 
ATOM   957  C  CG   . LEU A 1 65  ? 32.66700  -29.62400 -4.13500  1.000 35.21475  ? 65  LEU A CG   1 
ATOM   958  C  CD1  . LEU A 1 65  ? 33.27300  -31.01600 -4.30400  1.000 37.16761  ? 65  LEU A CD1  1 
ATOM   959  C  CD2  . LEU A 1 65  ? 33.59200  -28.59100 -4.72000  1.000 34.42255  ? 65  LEU A CD2  1 
ATOM   960  H  H    . LEU A 1 65  ? 30.50200  -28.57000 -2.69700  1.000 36.92000  ? 65  LEU A H    1 
ATOM   961  H  HA   . LEU A 1 65  ? 31.12300  -27.52200 -5.00500  1.000 37.52000  ? 65  LEU A HA   1 
ATOM   962  H  HB2  . LEU A 1 65  ? 30.74200  -30.24700 -4.35900  1.000 40.98000  ? 65  LEU A HB2  1 
ATOM   963  H  HB3  . LEU A 1 65  ? 31.39700  -29.75400 -5.72100  1.000 40.98000  ? 65  LEU A HB3  1 
ATOM   964  H  HG   . LEU A 1 65  ? 32.56900  -29.43600 -3.18900  1.000 42.26000  ? 65  LEU A HG   1 
ATOM   965  H  HD11 . LEU A 1 65  ? 34.13500  -31.04100 -3.86100  1.000 44.60000  ? 65  LEU A HD11 1 
ATOM   966  H  HD12 . LEU A 1 65  ? 32.67700  -31.67000 -3.90600  1.000 44.60000  ? 65  LEU A HD12 1 
ATOM   967  H  HD13 . LEU A 1 65  ? 33.38200  -31.20000 -5.25000  1.000 44.60000  ? 65  LEU A HD13 1 
ATOM   968  H  HD21 . LEU A 1 65  ? 34.48800  -28.74000 -4.38000  1.000 41.31000  ? 65  LEU A HD21 1 
ATOM   969  H  HD22 . LEU A 1 65  ? 33.58700  -28.67400 -5.68700  1.000 41.31000  ? 65  LEU A HD22 1 
ATOM   970  H  HD23 . LEU A 1 65  ? 33.28300  -27.70800 -4.46300  1.000 41.31000  ? 65  LEU A HD23 1 
ATOM   971  N  N    . ARG A 1 66  ? 28.17000  -28.74200 -4.86000  1.000 29.94570  ? 66  ARG A N    1 
ATOM   972  C  CA   . ARG A 1 66  ? 26.91700  -28.78900 -5.60600  1.000 33.95144  ? 66  ARG A CA   1 
ATOM   973  C  C    . ARG A 1 66  ? 26.48700  -27.38100 -5.99900  1.000 30.15888  ? 66  ARG A C    1 
ATOM   974  O  O    . ARG A 1 66  ? 26.04600  -27.14900 -7.13000  1.000 29.66408  ? 66  ARG A O    1 
ATOM   975  C  CB   . ARG A 1 66  ? 25.82500  -29.47400 -4.77400  1.000 33.60403  ? 66  ARG A CB   1 
ATOM   976  C  CG   . ARG A 1 66  ? 24.44200  -29.55600 -5.48000  1.000 38.69148  ? 66  ARG A CG   1 
ATOM   977  C  CD   . ARG A 1 66  ? 23.49200  -30.47300 -4.69600  1.000 38.86782  ? 66  ARG A CD   1 
ATOM   978  N  NE   . ARG A 1 66  ? 22.16200  -30.65400 -5.27300  1.000 39.72055  ? 66  ARG A NE   1 
ATOM   979  C  CZ   . ARG A 1 66  ? 21.86000  -31.48900 -6.25300  1.000 38.40724  ? 66  ARG A CZ   1 
ATOM   980  N  NH1  . ARG A 1 66  ? 22.79400  -32.21300 -6.85500  1.000 47.12933  ? 66  ARG A NH1  1 
ATOM   981  N  NH2  . ARG A 1 66  ? 20.58100  -31.61900 -6.62800  1.000 36.58597  ? 66  ARG A NH2  1 
ATOM   982  H  H    . ARG A 1 66  ? 28.12900  -29.04500 -4.05600  1.000 35.94000  ? 66  ARG A H    1 
ATOM   983  H  HA   . ARG A 1 66  ? 27.04200  -29.31500 -6.41200  1.000 40.74000  ? 66  ARG A HA   1 
ATOM   984  H  HB2  . ARG A 1 66  ? 26.10900  -30.38000 -4.57600  1.000 40.32000  ? 66  ARG A HB2  1 
ATOM   985  H  HB3  . ARG A 1 66  ? 25.70500  -28.97700 -3.95000  1.000 40.32000  ? 66  ARG A HB3  1 
ATOM   986  H  HG2  . ARG A 1 66  ? 24.04900  -28.67100 -5.52800  1.000 46.43000  ? 66  ARG A HG2  1 
ATOM   987  H  HG3  . ARG A 1 66  ? 24.55400  -29.91800 -6.37300  1.000 46.43000  ? 66  ARG A HG3  1 
ATOM   988  H  HD2  . ARG A 1 66  ? 23.89900  -31.35100 -4.63300  1.000 46.64000  ? 66  ARG A HD2  1 
ATOM   989  H  HD3  . ARG A 1 66  ? 23.37000  -30.09800 -3.80900  1.000 46.64000  ? 66  ARG A HD3  1 
ATOM   990  H  HE   . ARG A 1 66  ? 21.52200  -30.17800 -4.95000  1.000 47.67000  ? 66  ARG A HE   1 
ATOM   991  H  HH11 . ARG A 1 66  ? 23.61600  -32.14500 -6.60900  1.000 56.56000  ? 66  ARG A HH11 1 
ATOM   992  H  HH12 . ARG A 1 66  ? 22.57800  -32.75100 -7.49000  1.000 56.56000  ? 66  ARG A HH12 1 
ATOM   993  H  HH21 . ARG A 1 66  ? 19.96800  -31.16200 -6.23300  1.000 43.90000  ? 66  ARG A HH21 1 
ATOM   994  H  HH22 . ARG A 1 66  ? 20.37100  -32.15900 -7.26400  1.000 43.90000  ? 66  ARG A HH22 1 
ATOM   995  N  N    . VAL A 1 67  ? 26.63100  -26.42100 -5.07500  1.000 29.47985  ? 67  VAL A N    1 
ATOM   996  C  CA   . VAL A 1 67  ? 26.27400  -25.04200 -5.39300  1.000 31.88540  ? 67  VAL A CA   1 
ATOM   997  C  C    . VAL A 1 67  ? 27.23300  -24.46400 -6.42800  1.000 29.06138  ? 67  VAL A C    1 
ATOM   998  O  O    . VAL A 1 67  ? 26.81500  -23.79600 -7.38300  1.000 30.43523  ? 67  VAL A O    1 
ATOM   999  C  CB   . VAL A 1 67  ? 26.24200  -24.19300 -4.11400  1.000 30.84317  ? 67  VAL A CB   1 
ATOM   1000 C  CG1  . VAL A 1 67  ? 26.08400  -22.72600 -4.44900  1.000 33.07765  ? 67  VAL A CG1  1 
ATOM   1001 C  CG2  . VAL A 1 67  ? 25.12800  -24.68100 -3.17000  1.000 33.14082  ? 67  VAL A CG2  1 
ATOM   1002 H  H    . VAL A 1 67  ? 26.92700  -26.54300 -4.27600  1.000 35.38000  ? 67  VAL A H    1 
ATOM   1003 H  HA   . VAL A 1 67  ? 25.38400  -25.03800 -5.77800  1.000 38.26000  ? 67  VAL A HA   1 
ATOM   1004 H  HB   . VAL A 1 67  ? 27.08600  -24.29200 -3.64800  1.000 37.01000  ? 67  VAL A HB   1 
ATOM   1005 H  HG11 . VAL A 1 67  ? 25.80000  -22.24900 -3.65300  1.000 39.69000  ? 67  VAL A HG11 1 
ATOM   1006 H  HG12 . VAL A 1 67  ? 26.93600  -22.37800 -4.75600  1.000 39.69000  ? 67  VAL A HG12 1 
ATOM   1007 H  HG13 . VAL A 1 67  ? 25.41700  -22.63100 -5.14700  1.000 39.69000  ? 67  VAL A HG13 1 
ATOM   1008 H  HG21 . VAL A 1 67  ? 25.10800  -24.11200 -2.38500  1.000 39.77000  ? 67  VAL A HG21 1 
ATOM   1009 H  HG22 . VAL A 1 67  ? 24.27800  -24.63500 -3.63400  1.000 39.77000  ? 67  VAL A HG22 1 
ATOM   1010 H  HG23 . VAL A 1 67  ? 25.31400  -25.59700 -2.91000  1.000 39.77000  ? 67  VAL A HG23 1 
ATOM   1011 N  N    . GLU A 1 68  ? 28.53500  -24.70000 -6.25700  1.000 29.14034  ? 68  GLU A N    1 
ATOM   1012 C  CA   . GLU A 1 68  ? 29.49200  -24.18700 -7.23300  1.000 27.79807  ? 68  GLU A CA   1 
ATOM   1013 C  C    . GLU A 1 68  ? 29.22100  -24.77300 -8.60800  1.000 27.02692  ? 68  GLU A C    1 
ATOM   1014 O  O    . GLU A 1 68  ? 29.21400  -24.04400 -9.60400  1.000 29.49038  ? 68  GLU A O    1 
ATOM   1015 C  CB   . GLU A 1 68  ? 30.92800  -24.47800 -6.79300  1.000 27.89808  ? 68  GLU A CB   1 
ATOM   1016 C  CG   . GLU A 1 68  ? 31.38000  -23.58600 -5.63000  1.000 30.50366  ? 68  GLU A CG   1 
ATOM   1017 C  CD   . GLU A 1 68  ? 32.68200  -24.03900 -4.99100  1.000 32.54601  ? 68  GLU A CD   1 
ATOM   1018 O  OE1  . GLU A 1 68  ? 33.28300  -25.02600 -5.46300  1.000 29.76936  ? 68  GLU A OE1  1 
ATOM   1019 O  OE2  . GLU A 1 68  ? 33.09000  -23.42600 -3.96600  1.000 32.40389  ? 68  GLU A OE2  1 
ATOM   1020 H  H    . GLU A 1 68  ? 28.87900  -25.14100 -5.60400  1.000 34.97000  ? 68  GLU A H    1 
ATOM   1021 H  HA   . GLU A 1 68  ? 29.39900  -23.22300 -7.28300  1.000 33.36000  ? 68  GLU A HA   1 
ATOM   1022 H  HB2  . GLU A 1 68  ? 30.99000  -25.40200 -6.50600  1.000 33.48000  ? 68  GLU A HB2  1 
ATOM   1023 H  HB3  . GLU A 1 68  ? 31.52600  -24.32300 -7.54100  1.000 33.48000  ? 68  GLU A HB3  1 
ATOM   1024 H  HG2  . GLU A 1 68  ? 31.50900  -22.68300 -5.95900  1.000 36.60000  ? 68  GLU A HG2  1 
ATOM   1025 H  HG3  . GLU A 1 68  ? 30.69400  -23.59400 -4.94400  1.000 36.60000  ? 68  GLU A HG3  1 
ATOM   1026 N  N    . ALA A 1 69  ? 28.95700  -26.08200 -8.68100  1.000 27.21905  ? 69  ALA A N    1 
ATOM   1027 C  CA   . ALA A 1 69  ? 28.71000  -26.69400 -9.98600  1.000 28.99032  ? 69  ALA A CA   1 
ATOM   1028 C  C    . ALA A 1 69  ? 27.42600  -26.16500 -10.60800 1.000 29.23245  ? 69  ALA A C    1 
ATOM   1029 O  O    . ALA A 1 69  ? 27.38200  -25.89200 -11.81500 1.000 28.26392  ? 69  ALA A O    1 
ATOM   1030 C  CB   . ALA A 1 69  ? 28.65500  -28.21400 -9.86800  1.000 29.65882  ? 69  ALA A CB   1 
ATOM   1031 H  H    . ALA A 1 69  ? 28.91700  -26.61900 -8.01100  1.000 32.66000  ? 69  ALA A H    1 
ATOM   1032 H  HA   . ALA A 1 69  ? 29.45000  -26.47000 -10.57100 1.000 34.79000  ? 69  ALA A HA   1 
ATOM   1033 H  HB1  . ALA A 1 69  ? 28.49600  -28.59300 -10.74600 1.000 35.59000  ? 69  ALA A HB1  1 
ATOM   1034 H  HB2  . ALA A 1 69  ? 29.50000  -28.53500 -9.51700  1.000 35.59000  ? 69  ALA A HB2  1 
ATOM   1035 H  HB3  . ALA A 1 69  ? 27.93300  -28.45800 -9.26700  1.000 35.59000  ? 69  ALA A HB3  1 
ATOM   1036 N  N    . PHE A 1 70  ? 26.36700  -26.00500 -9.81400  1.000 27.13483  ? 70  PHE A N    1 
ATOM   1037 C  CA   . PHE A 1 70  ? 25.13800  -25.48500 -10.39000 1.000 28.63764  ? 70  PHE A CA   1 
ATOM   1038 C  C    . PHE A 1 70  ? 25.31800  -24.04900 -10.86700 1.000 29.10875  ? 70  PHE A C    1 
ATOM   1039 O  O    . PHE A 1 70  ? 24.86500  -23.69000 -11.95700 1.000 29.05875  ? 70  PHE A O    1 
ATOM   1040 C  CB   . PHE A 1 70  ? 23.96600  -25.52600 -9.42800  1.000 31.76433  ? 70  PHE A CB   1 
ATOM   1041 C  CG   . PHE A 1 70  ? 22.71400  -25.00900 -10.06100 1.000 30.45365  ? 70  PHE A CG   1 
ATOM   1042 C  CD1  . PHE A 1 70  ? 22.06500  -25.77900 -11.02400 1.000 32.01173  ? 70  PHE A CD1  1 
ATOM   1043 C  CD2  . PHE A 1 70  ? 22.26400  -23.72800 -9.81500  1.000 32.16701  ? 70  PHE A CD2  1 
ATOM   1044 C  CE1  . PHE A 1 70  ? 20.94100  -25.30500 -11.67100 1.000 29.29562  ? 70  PHE A CE1  1 
ATOM   1045 C  CE2  . PHE A 1 70  ? 21.12700  -23.24500 -10.46000 1.000 31.89593  ? 70  PHE A CE2  1 
ATOM   1046 C  CZ   . PHE A 1 70  ? 20.46900  -24.03500 -11.38600 1.000 30.08519  ? 70  PHE A CZ   1 
ATOM   1047 H  H    . PHE A 1 70  ? 26.33800  -26.18500 -8.97300  1.000 32.56000  ? 70  PHE A H    1 
ATOM   1048 H  HA   . PHE A 1 70  ? 24.92300  -26.06900 -11.13400 1.000 34.36000  ? 70  PHE A HA   1 
ATOM   1049 H  HB2  . PHE A 1 70  ? 23.81100  -26.44300 -9.15000  1.000 38.12000  ? 70  PHE A HB2  1 
ATOM   1050 H  HB3  . PHE A 1 70  ? 24.16700  -24.97500 -8.65500  1.000 38.12000  ? 70  PHE A HB3  1 
ATOM   1051 H  HD1  . PHE A 1 70  ? 22.39300  -26.62400 -11.23400 1.000 38.41000  ? 70  PHE A HD1  1 
ATOM   1052 H  HD2  . PHE A 1 70  ? 22.72100  -23.18400 -9.21600  1.000 38.60000  ? 70  PHE A HD2  1 
ATOM   1053 H  HE1  . PHE A 1 70  ? 20.50300  -25.83700 -12.29600 1.000 35.15000  ? 70  PHE A HE1  1 
ATOM   1054 H  HE2  . PHE A 1 70  ? 20.81100  -22.39200 -10.26800 1.000 38.27000  ? 70  PHE A HE2  1 
ATOM   1055 H  HZ   . PHE A 1 70  ? 19.71000  -23.71300 -11.81600 1.000 36.10000  ? 70  PHE A HZ   1 
ATOM   1056 N  N    . GLU A 1 71  ? 25.97600  -23.20800 -10.06700 1.000 28.17180  ? 71  GLU A N    1 
ATOM   1057 C  CA   . GLU A 1 71  ? 26.18500  -21.82500 -10.49800 1.000 28.98505  ? 71  GLU A CA   1 
ATOM   1058 C  C    . GLU A 1 71  ? 26.99900  -21.75600 -11.78400 1.000 27.72701  ? 71  GLU A C    1 
ATOM   1059 O  O    . GLU A 1 71  ? 26.73200  -20.91200 -12.64600 1.000 31.38008  ? 71  GLU A O    1 
ATOM   1060 C  CB   . GLU A 1 71  ? 26.85900  -21.00600 -9.40000  1.000 30.74842  ? 71  GLU A CB   1 
ATOM   1061 C  CG   . GLU A 1 71  ? 25.93700  -20.81200 -8.19900  1.000 42.34455  ? 71  GLU A CG   1 
ATOM   1062 C  CD   . GLU A 1 71  ? 24.67700  -19.99000 -8.52800  1.000 58.88864  ? 71  GLU A CD   1 
ATOM   1063 O  OE1  . GLU A 1 71  ? 24.81000  -18.79200 -8.86700  1.000 55.63299  ? 71  GLU A OE1  1 
ATOM   1064 O  OE2  . GLU A 1 71  ? 23.55000  -20.55500 -8.43600  1.000 54.90132  ? 71  GLU A OE2  1 
ATOM   1065 H  H    . GLU A 1 71  ? 26.30000  -23.40500 -9.29600  1.000 33.81000  ? 71  GLU A H    1 
ATOM   1066 H  HA   . GLU A 1 71  ? 25.31500  -21.43100 -10.66700 1.000 34.78000  ? 71  GLU A HA   1 
ATOM   1067 H  HB2  . GLU A 1 71  ? 27.65700  -21.46700 -9.10000  1.000 36.90000  ? 71  GLU A HB2  1 
ATOM   1068 H  HB3  . GLU A 1 71  ? 27.09200  -20.13200 -9.75000  1.000 36.90000  ? 71  GLU A HB3  1 
ATOM   1069 H  HG2  . GLU A 1 71  ? 25.65100  -21.68200 -7.87900  1.000 50.81000  ? 71  GLU A HG2  1 
ATOM   1070 H  HG3  . GLU A 1 71  ? 26.42400  -20.34500 -7.50200  1.000 50.81000  ? 71  GLU A HG3  1 
ATOM   1071 N  N    . TYR A 1 72  ? 27.98200  -22.65400 -11.95300 1.000 28.15338  ? 72  TYR A N    1 
ATOM   1072 C  CA   . TYR A 1 72  ? 28.84800  -22.56000 -13.13100 1.000 28.62448  ? 72  TYR A CA   1 
ATOM   1073 C  C    . TYR A 1 72  ? 28.22300  -23.22100 -14.35600 1.000 29.84042  ? 72  TYR A C    1 
ATOM   1074 O  O    . TYR A 1 72  ? 28.28600  -22.66800 -15.46400 1.000 29.11665  ? 72  TYR A O    1 
ATOM   1075 C  CB   . TYR A 1 72  ? 30.22300  -23.18300 -12.84600 1.000 28.88504  ? 72  TYR A CB   1 
ATOM   1076 C  CG   . TYR A 1 72  ? 31.30400  -22.74500 -13.81200 1.000 27.68753  ? 72  TYR A CG   1 
ATOM   1077 C  CD1  . TYR A 1 72  ? 31.65600  -21.40600 -13.93200 1.000 29.15613  ? 72  TYR A CD1  1 
ATOM   1078 C  CD2  . TYR A 1 72  ? 31.96400  -23.66900 -14.60700 1.000 28.30866  ? 72  TYR A CD2  1 
ATOM   1079 C  CE1  . TYR A 1 72  ? 32.63100  -20.98700 -14.83500 1.000 28.45078  ? 72  TYR A CE1  1 
ATOM   1080 C  CE2  . TYR A 1 72  ? 32.94600  -23.27100 -15.49900 1.000 27.62700  ? 72  TYR A CE2  1 
ATOM   1081 C  CZ   . TYR A 1 72  ? 33.26900  -21.93000 -15.61900 1.000 29.85358  ? 72  TYR A CZ   1 
ATOM   1082 O  OH   . TYR A 1 72  ? 34.23500  -21.51800 -16.51800 1.000 29.85358  ? 72  TYR A OH   1 
ATOM   1083 H  H    . TYR A 1 72  ? 28.16000  -23.30200 -11.41700 1.000 33.79000  ? 72  TYR A H    1 
ATOM   1084 H  HA   . TYR A 1 72  ? 28.97800  -21.62000 -13.32700 1.000 34.35000  ? 72  TYR A HA   1 
ATOM   1085 H  HB2  . TYR A 1 72  ? 30.50200  -22.92600 -11.95300 1.000 34.66000  ? 72  TYR A HB2  1 
ATOM   1086 H  HB3  . TYR A 1 72  ? 30.14600  -24.14800 -12.90400 1.000 34.66000  ? 72  TYR A HB3  1 
ATOM   1087 H  HD1  . TYR A 1 72  ? 31.23000  -20.77500 -13.39800 1.000 34.99000  ? 72  TYR A HD1  1 
ATOM   1088 H  HD2  . TYR A 1 72  ? 31.74400  -24.57100 -14.54100 1.000 33.97000  ? 72  TYR A HD2  1 
ATOM   1089 H  HE1  . TYR A 1 72  ? 32.85000  -20.08600 -14.90900 1.000 34.14000  ? 72  TYR A HE1  1 
ATOM   1090 H  HE2  . TYR A 1 72  ? 33.38900  -23.90400 -16.01700 1.000 33.15000  ? 72  TYR A HE2  1 
ATOM   1091 H  HH   . TYR A 1 72  ? 34.30900  -20.68100 -16.49500 1.000 35.82000  ? 72  TYR A HH   1 
ATOM   1092 N  N    . TYR A 1 73  ? 27.60500  -24.39200 -14.19600 1.000 28.09021  ? 73  TYR A N    1 
ATOM   1093 C  CA   . TYR A 1 73  ? 27.12000  -25.14900 -15.35700 1.000 26.12155  ? 73  TYR A CA   1 
ATOM   1094 C  C    . TYR A 1 73  ? 25.61000  -25.10500 -15.54900 1.000 27.60594  ? 73  TYR A C    1 
ATOM   1095 O  O    . TYR A 1 73  ? 25.13300  -25.42500 -16.63800 1.000 27.76649  ? 73  TYR A O    1 
ATOM   1096 C  CB   . TYR A 1 73  ? 27.54500  -26.62100 -15.23900 1.000 26.17419  ? 73  TYR A CB   1 
ATOM   1097 C  CG   . TYR A 1 73  ? 29.03300  -26.86100 -15.11200 1.000 28.32971  ? 73  TYR A CG   1 
ATOM   1098 C  CD1  . TYR A 1 73  ? 29.88700  -26.75000 -16.20100 1.000 26.07681  ? 73  TYR A CD1  1 
ATOM   1099 C  CD2  . TYR A 1 73  ? 29.59300  -27.21100 -13.89100 1.000 27.21116  ? 73  TYR A CD2  1 
ATOM   1100 C  CE1  . TYR A 1 73  ? 31.25400  -26.98700 -16.08500 1.000 26.24262  ? 73  TYR A CE1  1 
ATOM   1101 C  CE2  . TYR A 1 73  ? 30.94600  -27.45400 -13.78200 1.000 25.87415  ? 73  TYR A CE2  1 
ATOM   1102 C  CZ   . TYR A 1 73  ? 31.77200  -27.33300 -14.84900 1.000 28.70607  ? 73  TYR A CZ   1 
ATOM   1103 O  OH   . TYR A 1 73  ? 33.10800  -27.56100 -14.69200 1.000 29.59039  ? 73  TYR A OH   1 
ATOM   1104 H  H    . TYR A 1 73  ? 27.45700  -24.76700 -13.43700 1.000 33.71000  ? 73  TYR A H    1 
ATOM   1105 H  HA   . TYR A 1 73  ? 27.52400  -24.77100 -16.15400 1.000 31.34000  ? 73  TYR A HA   1 
ATOM   1106 H  HB2  . TYR A 1 73  ? 27.12400  -26.99800 -14.45100 1.000 31.41000  ? 73  TYR A HB2  1 
ATOM   1107 H  HB3  . TYR A 1 73  ? 27.24300  -27.09100 -16.03300 1.000 31.41000  ? 73  TYR A HB3  1 
ATOM   1108 H  HD1  . TYR A 1 73  ? 29.53800  -26.51100 -17.02900 1.000 31.29000  ? 73  TYR A HD1  1 
ATOM   1109 H  HD2  . TYR A 1 73  ? 29.05100  -27.28100 -13.13900 1.000 32.65000  ? 73  TYR A HD2  1 
ATOM   1110 H  HE1  . TYR A 1 73  ? 31.81000  -26.91300 -16.82700 1.000 31.49000  ? 73  TYR A HE1  1 
ATOM   1111 H  HE2  . TYR A 1 73  ? 31.29900  -27.70500 -12.95900 1.000 31.05000  ? 73  TYR A HE2  1 
ATOM   1112 H  HH   . TYR A 1 73  ? 33.26400  -27.82800 -13.91000 1.000 35.51000  ? 73  TYR A HH   1 
ATOM   1113 N  N    . HIS A 1 74  ? 24.85000  -24.74300 -14.52000 1.000 26.20051  ? 74  HIS A N    1 
ATOM   1114 C  CA   . HIS A 1 74  ? 23.39100  -24.76000 -14.55500 1.000 26.11366  ? 74  HIS A CA   1 
ATOM   1115 C  C    . HIS A 1 74  ? 22.85400  -26.17000 -14.77100 1.000 30.59314  ? 74  HIS A C    1 
ATOM   1116 O  O    . HIS A 1 74  ? 21.89200  -26.37800 -15.50300 1.000 30.63525  ? 74  HIS A O    1 
ATOM   1117 C  CB   . HIS A 1 74  ? 22.82900  -23.80900 -15.61400 1.000 28.81924  ? 74  HIS A CB   1 
ATOM   1118 C  CG   . HIS A 1 74  ? 23.06200  -22.36200 -15.32900 1.000 31.76697  ? 74  HIS A CG   1 
ATOM   1119 N  ND1  . HIS A 1 74  ? 22.61200  -21.36200 -16.16600 1.000 33.07502  ? 74  HIS A ND1  1 
ATOM   1120 C  CD2  . HIS A 1 74  ? 23.68100  -21.74100 -14.29900 1.000 31.77223  ? 74  HIS A CD2  1 
ATOM   1121 C  CE1  . HIS A 1 74  ? 22.93900  -20.18600 -15.65600 1.000 32.30387  ? 74  HIS A CE1  1 
ATOM   1122 N  NE2  . HIS A 1 74  ? 23.60800  -20.38900 -14.53700 1.000 32.26703  ? 74  HIS A NE2  1 
ATOM   1123 H  H    . HIS A 1 74  ? 25.16600  -24.47600 -13.76600 1.000 31.44000  ? 74  HIS A H    1 
ATOM   1124 H  HA   . HIS A 1 74  ? 23.08000  -24.45200 -13.68900 1.000 31.34000  ? 74  HIS A HA   1 
ATOM   1125 H  HB2  . HIS A 1 74  ? 23.24700  -24.01100 -16.46500 1.000 34.58000  ? 74  HIS A HB2  1 
ATOM   1126 H  HB3  . HIS A 1 74  ? 21.87000  -23.94500 -15.67500 1.000 34.58000  ? 74  HIS A HB3  1 
ATOM   1127 H  HD1  . HIS A 1 74  ? 22.18700  -21.48400 -16.90300 1.000 39.69000  ? 74  HIS A HD1  1 
ATOM   1128 H  HD2  . HIS A 1 74  ? 24.08200  -22.15200 -13.56700 1.000 38.13000  ? 74  HIS A HD2  1 
ATOM   1129 H  HE1  . HIS A 1 74  ? 22.73100  -19.35700 -16.02300 1.000 38.76000  ? 74  HIS A HE1  1 
ATOM   1130 H  HE2  . HIS A 1 74  ? 23.94500  -19.77500 -14.03700 1.000 38.72000  ? 74  HIS A HE2  1 
ATOM   1131 N  N    . THR A 1 75  ? 23.49100  -27.14800 -14.14300 1.000 27.39802  ? 75  THR A N    1 
ATOM   1132 C  CA   . THR A 1 75  ? 22.99200  -28.51400 -14.14200 1.000 29.50091  ? 75  THR A CA   1 
ATOM   1133 C  C    . THR A 1 75  ? 23.22000  -29.10700 -12.76200 1.000 30.31416  ? 75  THR A C    1 
ATOM   1134 O  O    . THR A 1 75  ? 24.11300  -28.68100 -12.02100 1.000 31.69327  ? 75  THR A O    1 
ATOM   1135 C  CB   . THR A 1 75  ? 23.66800  -29.38100 -15.23400 1.000 32.46179  ? 75  THR A CB   1 
ATOM   1136 O  OG1  . THR A 1 75  ? 23.10100  -30.69300 -15.23100 1.000 32.64076  ? 75  THR A OG1  1 
ATOM   1137 C  CG2  . THR A 1 75  ? 25.14700  -29.50100 -14.96300 1.000 36.10170  ? 75  THR A CG2  1 
ATOM   1138 H  H    . THR A 1 75  ? 24.22300  -27.04300 -13.70500 1.000 32.88000  ? 75  THR A H    1 
ATOM   1139 H  HA   . THR A 1 75  ? 22.03900  -28.52200 -14.32500 1.000 35.40000  ? 75  THR A HA   1 
ATOM   1140 H  HB   . THR A 1 75  ? 23.53300  -28.96600 -16.10000 1.000 38.95000  ? 75  THR A HB   1 
ATOM   1141 H  HG1  . THR A 1 75  ? 23.44600  -31.15600 -15.84100 1.000 39.17000  ? 75  THR A HG1  1 
ATOM   1142 H  HG21 . THR A 1 75  ? 25.60700  -29.80500 -15.76100 1.000 43.32000  ? 75  THR A HG21 1 
ATOM   1143 H  HG22 . THR A 1 75  ? 25.50700  -28.63900 -14.70100 1.000 43.32000  ? 75  THR A HG22 1 
ATOM   1144 H  HG23 . THR A 1 75  ? 25.30300  -30.13700 -14.24800 1.000 43.32000  ? 75  THR A HG23 1 
ATOM   1145 N  N    . THR A 1 76  ? 22.35000  -30.04900 -12.40400 1.000 28.85609  ? 76  THR A N    1 
ATOM   1146 C  CA   . THR A 1 76  ? 22.56100  -30.95900 -11.29000 1.000 29.30088  ? 76  THR A CA   1 
ATOM   1147 C  C    . THR A 1 76  ? 22.50700  -32.41200 -11.75500 1.000 28.74292  ? 76  THR A C    1 
ATOM   1148 O  O    . THR A 1 76  ? 22.21100  -33.30500 -10.95700 1.000 30.91160  ? 76  THR A O    1 
ATOM   1149 C  CB   . THR A 1 76  ? 21.54400  -30.71200 -10.17500 1.000 27.31906  ? 76  THR A CB   1 
ATOM   1150 O  OG1  . THR A 1 76  ? 20.20900  -30.80600 -10.69400 1.000 27.34275  ? 76  THR A OG1  1 
ATOM   1151 C  CG2  . THR A 1 76  ? 21.75200  -29.34200 -9.55900  1.000 31.77749  ? 76  THR A CG2  1 
ATOM   1152 H  H    . THR A 1 76  ? 21.60300  -30.18300 -12.80800 1.000 34.63000  ? 76  THR A H    1 
ATOM   1153 H  HA   . THR A 1 76  ? 23.43800  -30.79200 -10.91100 1.000 35.16000  ? 76  THR A HA   1 
ATOM   1154 H  HB   . THR A 1 76  ? 21.66100  -31.38100 -9.48200  1.000 32.78000  ? 76  THR A HB   1 
ATOM   1155 H  HG1  . THR A 1 76  ? 19.65600  -30.83100 -10.06200 1.000 32.81000  ? 76  THR A HG1  1 
ATOM   1156 H  HG21 . THR A 1 76  ? 21.09100  -29.18500 -8.86600  1.000 38.13000  ? 76  THR A HG21 1 
ATOM   1157 H  HG22 . THR A 1 76  ? 22.63800  -29.28400 -9.16800  1.000 38.13000  ? 76  THR A HG22 1 
ATOM   1158 H  HG23 . THR A 1 76  ? 21.66300  -28.65500 -10.23900 1.000 38.13000  ? 76  THR A HG23 1 
ATOM   1159 N  N    . ASP A 1 77  ? 22.74000  -32.66000 -13.03600 1.000 29.07980  ? 77  ASP A N    1 
ATOM   1160 C  CA   . ASP A 1 77  ? 22.87600  -34.04200 -13.48800 1.000 31.95120  ? 77  ASP A CA   1 
ATOM   1161 C  C    . ASP A 1 77  ? 24.08500  -34.66400 -12.79900 1.000 28.01652  ? 77  ASP A C    1 
ATOM   1162 O  O    . ASP A 1 77  ? 25.19700  -34.12600 -12.92000 1.000 27.86124  ? 77  ASP A O    1 
ATOM   1163 C  CB   . ASP A 1 77  ? 23.03900  -34.10400 -14.99300 1.000 31.20637  ? 77  ASP A CB   1 
ATOM   1164 C  CG   . ASP A 1 77  ? 22.84900  -35.51200 -15.53500 1.000 40.50222  ? 77  ASP A CG   1 
ATOM   1165 O  OD1  . ASP A 1 77  ? 22.25400  -36.35600 -14.83000 1.000 44.63430  ? 77  ASP A OD1  1 
ATOM   1166 O  OD2  . ASP A 1 77  ? 23.28400  -35.78800 -16.65500 1.000 42.95252  ? 77  ASP A OD2  1 
ATOM   1167 H  H    . ASP A 1 77  ? 22.82200  -32.06400 -13.65000 1.000 34.90000  ? 77  ASP A H    1 
ATOM   1168 H  HA   . ASP A 1 77  ? 22.07700  -34.54400 -13.26200 1.000 38.34000  ? 77  ASP A HA   1 
ATOM   1169 H  HB2  . ASP A 1 77  ? 22.37700  -33.52800 -15.40800 1.000 37.44000  ? 77  ASP A HB2  1 
ATOM   1170 H  HB3  . ASP A 1 77  ? 23.93200  -33.80700 -15.22900 1.000 37.44000  ? 77  ASP A HB3  1 
ATOM   1171 N  N    . PRO A 1 78  ? 23.92400  -35.77500 -12.07300 1.000 31.52746  ? 78  PRO A N    1 
ATOM   1172 C  CA   . PRO A 1 78  ? 25.03100  -36.26800 -11.24400 1.000 34.10409  ? 78  PRO A CA   1 
ATOM   1173 C  C    . PRO A 1 78  ? 26.28200  -36.63900 -12.01600 1.000 31.80381  ? 78  PRO A C    1 
ATOM   1174 O  O    . PRO A 1 78  ? 27.39500  -36.53900 -11.47900 1.000 34.84102  ? 78  PRO A O    1 
ATOM   1175 C  CB   . PRO A 1 78  ? 24.42500  -37.50000 -10.55400 1.000 38.99415  ? 78  PRO A CB   1 
ATOM   1176 C  CG   . PRO A 1 78  ? 22.95700  -37.28500 -10.60100 1.000 37.99929  ? 78  PRO A CG   1 
ATOM   1177 C  CD   . PRO A 1 78  ? 22.69000  -36.56000 -11.88100 1.000 35.60690  ? 78  PRO A CD   1 
ATOM   1178 H  HA   . PRO A 1 78  ? 25.25800  -35.59000 -10.58700 1.000 40.92000  ? 78  PRO A HA   1 
ATOM   1179 H  HB2  . PRO A 1 78  ? 24.67400  -38.30400 -11.03600 1.000 46.79000  ? 78  PRO A HB2  1 
ATOM   1180 H  HB3  . PRO A 1 78  ? 24.73900  -37.55200 -9.63700  1.000 46.79000  ? 78  PRO A HB3  1 
ATOM   1181 H  HG2  . PRO A 1 78  ? 22.50100  -38.14200 -10.59000 1.000 45.60000  ? 78  PRO A HG2  1 
ATOM   1182 H  HG3  . PRO A 1 78  ? 22.67900  -36.75200 -9.84000  1.000 45.60000  ? 78  PRO A HG3  1 
ATOM   1183 H  HD2  . PRO A 1 78  ? 22.55800  -37.18400 -12.61200 1.000 42.73000  ? 78  PRO A HD2  1 
ATOM   1184 H  HD3  . PRO A 1 78  ? 21.91900  -35.97900 -11.79700 1.000 42.73000  ? 78  PRO A HD3  1 
ATOM   1185 N  N    . SER A 1 79  ? 26.14400  -37.08000 -13.25100 1.000 34.54098  ? 79  SER A N    1 
ATOM   1186 C  CA   . SER A 1 79  ? 27.30200  -37.52400 -14.00900 1.000 31.08531  ? 79  SER A CA   1 
ATOM   1187 C  C    . SER A 1 79  ? 27.86700  -36.45000 -14.91800 1.000 35.91483  ? 79  SER A C    1 
ATOM   1188 O  O    . SER A 1 79  ? 28.82000  -36.72800 -15.64200 1.000 33.87775  ? 79  SER A O    1 
ATOM   1189 C  CB   . SER A 1 79  ? 26.91400  -38.75600 -14.82100 1.000 37.05707  ? 79  SER A CB   1 
ATOM   1190 O  OG   . SER A 1 79  ? 25.99600  -38.39600 -15.83400 1.000 42.00240  ? 79  SER A OG   1 
ATOM   1191 H  H    . SER A 1 79  ? 25.39600  -37.13200 -13.67100 1.000 41.45000  ? 79  SER A H    1 
ATOM   1192 H  HA   . SER A 1 79  ? 28.01300  -37.77300 -13.39800 1.000 37.30000  ? 79  SER A HA   1 
ATOM   1193 H  HB2  . SER A 1 79  ? 27.70900  -39.13300 -15.22900 1.000 44.47000  ? 79  SER A HB2  1 
ATOM   1194 H  HB3  . SER A 1 79  ? 26.50100  -39.40900 -14.23400 1.000 44.47000  ? 79  SER A HB3  1 
ATOM   1195 H  HG   . SER A 1 79  ? 25.77100  -39.07600 -16.27200 1.000 50.40000  ? 79  SER A HG   1 
ATOM   1196 N  N    . PHE A 1 80  ? 27.32100  -35.23100 -14.88800 1.000 30.12993  ? 80  PHE A N    1 
ATOM   1197 C  CA   . PHE A 1 80  ? 27.76500  -34.20700 -15.82700 1.000 28.84293  ? 80  PHE A CA   1 
ATOM   1198 C  C    . PHE A 1 80  ? 29.28200  -34.02500 -15.82100 1.000 31.87224  ? 80  PHE A C    1 
ATOM   1199 O  O    . PHE A 1 80  ? 29.91000  -33.94400 -16.87400 1.000 30.04044  ? 80  PHE A O    1 
ATOM   1200 C  CB   . PHE A 1 80  ? 27.10900  -32.86800 -15.51200 1.000 28.60080  ? 80  PHE A CB   1 
ATOM   1201 C  CG   . PHE A 1 80  ? 27.42800  -31.78900 -16.50800 1.000 26.32158  ? 80  PHE A CG   1 
ATOM   1202 C  CD1  . PHE A 1 80  ? 26.66200  -31.61400 -17.64600 1.000 27.62963  ? 80  PHE A CD1  1 
ATOM   1203 C  CD2  . PHE A 1 80  ? 28.51700  -30.96500 -16.33100 1.000 27.37170  ? 80  PHE A CD2  1 
ATOM   1204 C  CE1  . PHE A 1 80  ? 26.95400  -30.61800 -18.53100 1.000 25.48727  ? 80  PHE A CE1  1 
ATOM   1205 C  CE2  . PHE A 1 80  ? 28.82100  -29.98600 -17.25400 1.000 27.34802  ? 80  PHE A CE2  1 
ATOM   1206 C  CZ   . PHE A 1 80  ? 28.04400  -29.82700 -18.35800 1.000 28.67449  ? 80  PHE A CZ   1 
ATOM   1207 H  H    . PHE A 1 80  ? 26.70400  -34.97900 -14.34400 1.000 36.15000  ? 80  PHE A H    1 
ATOM   1208 H  HA   . PHE A 1 80  ? 27.49100  -34.50000 -16.71100 1.000 34.61000  ? 80  PHE A HA   1 
ATOM   1209 H  HB2  . PHE A 1 80  ? 26.14600  -32.98600 -15.50300 1.000 34.32000  ? 80  PHE A HB2  1 
ATOM   1210 H  HB3  . PHE A 1 80  ? 27.41500  -32.56700 -14.64200 1.000 34.32000  ? 80  PHE A HB3  1 
ATOM   1211 H  HD1  . PHE A 1 80  ? 25.94200  -32.18000 -17.80900 1.000 33.16000  ? 80  PHE A HD1  1 
ATOM   1212 H  HD2  . PHE A 1 80  ? 29.05500  -31.07100 -15.58000 1.000 32.85000  ? 80  PHE A HD2  1 
ATOM   1213 H  HE1  . PHE A 1 80  ? 26.39900  -30.47800 -19.26400 1.000 30.59000  ? 80  PHE A HE1  1 
ATOM   1214 H  HE2  . PHE A 1 80  ? 29.55800  -29.43400 -17.12100 1.000 32.82000  ? 80  PHE A HE2  1 
ATOM   1215 H  HZ   . PHE A 1 80  ? 28.25700  -29.18000 -18.99100 1.000 34.41000  ? 80  PHE A HZ   1 
ATOM   1216 N  N    . LEU A 1 81  ? 29.88800  -33.90100 -14.64000 1.000 29.25877  ? 81  LEU A N    1 
ATOM   1217 C  CA   . LEU A 1 81  ? 31.31400  -33.59600 -14.59800 1.000 29.26404  ? 81  LEU A CA   1 
ATOM   1218 C  C    . LEU A 1 81  ? 32.14700  -34.72700 -15.18800 1.000 29.80621  ? 81  LEU A C    1 
ATOM   1219 O  O    . LEU A 1 81  ? 33.17300  -34.48000 -15.82700 1.000 31.60905  ? 81  LEU A O    1 
ATOM   1220 C  CB   . LEU A 1 81  ? 31.76000  -33.31000 -13.16500 1.000 33.66193  ? 81  LEU A CB   1 
ATOM   1221 C  CG   . LEU A 1 81  ? 31.86500  -31.87200 -12.67300 1.000 38.97046  ? 81  LEU A CG   1 
ATOM   1222 C  CD1  . LEU A 1 81  ? 32.81500  -31.06300 -13.53900 1.000 41.08387  ? 81  LEU A CD1  1 
ATOM   1223 C  CD2  . LEU A 1 81  ? 30.50900  -31.18600 -12.62400 1.000 39.04942  ? 81  LEU A CD2  1 
ATOM   1224 H  H    . LEU A 1 81  ? 29.50700  -33.98600 -13.87400 1.000 35.11000  ? 81  LEU A H    1 
ATOM   1225 H  HA   . LEU A 1 81  ? 31.46600  -32.79700 -15.12700 1.000 35.12000  ? 81  LEU A HA   1 
ATOM   1226 H  HB2  . LEU A 1 81  ? 31.12900  -33.75200 -12.57500 1.000 40.39000  ? 81  LEU A HB2  1 
ATOM   1227 H  HB3  . LEU A 1 81  ? 32.64300  -33.69700 -13.05700 1.000 40.39000  ? 81  LEU A HB3  1 
ATOM   1228 H  HG   . LEU A 1 81  ? 32.21600  -31.90300 -11.76900 1.000 46.77000  ? 81  LEU A HG   1 
ATOM   1229 H  HD11 . LEU A 1 81  ? 32.98000  -30.20700 -13.11300 1.000 49.30000  ? 81  LEU A HD11 1 
ATOM   1230 H  HD12 . LEU A 1 81  ? 33.64800  -31.55000 -13.63400 1.000 49.30000  ? 81  LEU A HD12 1 
ATOM   1231 H  HD13 . LEU A 1 81  ? 32.41100  -30.92700 -14.41000 1.000 49.30000  ? 81  LEU A HD13 1 
ATOM   1232 H  HD21 . LEU A 1 81  ? 30.62300  -30.28500 -12.28200 1.000 46.86000  ? 81  LEU A HD21 1 
ATOM   1233 H  HD22 . LEU A 1 81  ? 30.13700  -31.15600 -13.51900 1.000 46.86000  ? 81  LEU A HD22 1 
ATOM   1234 H  HD23 . LEU A 1 81  ? 29.92100  -31.69000 -12.03900 1.000 46.86000  ? 81  LEU A HD23 1 
ATOM   1235 N  N    . GLY A 1 82  ? 31.73500  -35.97500 -14.97300 1.000 30.35364  ? 82  GLY A N    1 
ATOM   1236 C  CA   . GLY A 1 82  ? 32.47500  -37.09300 -15.54100 1.000 32.47495  ? 82  GLY A CA   1 
ATOM   1237 C  C    . GLY A 1 82  ? 32.34000  -37.12900 -17.05100 1.000 33.81458  ? 82  GLY A C    1 
ATOM   1238 O  O    . GLY A 1 82  ? 33.29200  -37.44700 -17.77300 1.000 33.06712  ? 82  GLY A O    1 
ATOM   1239 H  H    . GLY A 1 82  ? 31.04400  -36.19600 -14.51100 1.000 36.42000  ? 82  GLY A H    1 
ATOM   1240 H  HA2  . GLY A 1 82  ? 33.41400  -37.01000 -15.31500 1.000 38.97000  ? 82  GLY A HA2  1 
ATOM   1241 H  HA3  . GLY A 1 82  ? 32.13500  -37.92600 -15.17900 1.000 38.97000  ? 82  GLY A HA3  1 
ATOM   1242 N  N    . ARG A 1 83  ? 31.16000  -36.78300 -17.54700 1.000 30.35890  ? 83  ARG A N    1 
ATOM   1243 C  CA   . ARG A 1 83  ? 30.95300  -36.73700 -18.98900 1.000 28.86136  ? 83  ARG A CA   1 
ATOM   1244 C  C    . ARG A 1 83  ? 31.74100  -35.59000 -19.60800 1.000 30.57735  ? 83  ARG A C    1 
ATOM   1245 O  O    . ARG A 1 83  ? 32.32200  -35.74400 -20.68600 1.000 28.30076  ? 83  ARG A O    1 
ATOM   1246 C  CB   . ARG A 1 83  ? 29.44700  -36.65100 -19.26300 1.000 30.96687  ? 83  ARG A CB   1 
ATOM   1247 C  CG   . ARG A 1 83  ? 28.78100  -37.98200 -18.85600 1.000 39.98901  ? 83  ARG A CG   1 
ATOM   1248 C  CD   . ARG A 1 83  ? 27.28300  -38.08500 -19.06300 1.000 46.95563  ? 83  ARG A CD   1 
ATOM   1249 N  NE   . ARG A 1 83  ? 26.50200  -37.04400 -18.40900 1.000 44.86591  ? 83  ARG A NE   1 
ATOM   1250 C  CZ   . ARG A 1 83  ? 26.07000  -35.96400 -19.03800 1.000 37.94402  ? 83  ARG A CZ   1 
ATOM   1251 N  NH1  . ARG A 1 83  ? 26.47600  -35.68600 -20.25400 1.000 33.44875  ? 83  ARG A NH1  1 
ATOM   1252 N  NH2  . ARG A 1 83  ? 25.20900  -35.15700 -18.43000 1.000 36.88600  ? 83  ARG A NH2  1 
ATOM   1253 H  H    . ARG A 1 83  ? 30.47000  -36.57200 -17.07800 1.000 36.43000  ? 83  ARG A H    1 
ATOM   1254 H  HA   . ARG A 1 83  ? 31.27500  -37.54700 -19.41500 1.000 34.63000  ? 83  ARG A HA   1 
ATOM   1255 H  HB2  . ARG A 1 83  ? 29.05800  -35.93100 -18.74100 1.000 37.16000  ? 83  ARG A HB2  1 
ATOM   1256 H  HB3  . ARG A 1 83  ? 29.29200  -36.49600 -20.20800 1.000 37.16000  ? 83  ARG A HB3  1 
ATOM   1257 H  HG2  . ARG A 1 83  ? 29.18800  -38.69300 -19.37500 1.000 47.99000  ? 83  ARG A HG2  1 
ATOM   1258 H  HG3  . ARG A 1 83  ? 28.94600  -38.12500 -17.91100 1.000 47.99000  ? 83  ARG A HG3  1 
ATOM   1259 H  HD2  . ARG A 1 83  ? 27.09800  -38.03300 -20.01400 1.000 56.35000  ? 83  ARG A HD2  1 
ATOM   1260 H  HD3  . ARG A 1 83  ? 26.98100  -38.93800 -18.71300 1.000 56.35000  ? 83  ARG A HD3  1 
ATOM   1261 H  HE   . ARG A 1 83  ? 26.31400  -37.13500 -17.57500 1.000 53.84000  ? 83  ARG A HE   1 
ATOM   1262 H  HH11 . ARG A 1 83  ? 27.03100  -36.20900 -20.65200 1.000 40.14000  ? 83  ARG A HH11 1 
ATOM   1263 H  HH12 . ARG A 1 83  ? 26.18800  -34.98100 -20.65300 1.000 40.14000  ? 83  ARG A HH12 1 
ATOM   1264 H  HH21 . ARG A 1 83  ? 24.93700  -35.33800 -17.63500 1.000 44.27000  ? 83  ARG A HH21 1 
ATOM   1265 H  HH22 . ARG A 1 83  ? 24.92200  -34.45300 -18.83300 1.000 44.27000  ? 83  ARG A HH22 1 
ATOM   1266 N  N    . TYR A 1 84  ? 31.82000  -34.45200 -18.91700 1.000 28.08758  ? 84  TYR A N    1 
ATOM   1267 C  CA   . TYR A 1 84  ? 32.61500  -33.32900 -19.40800 1.000 26.62161  ? 84  TYR A CA   1 
ATOM   1268 C  C    . TYR A 1 84  ? 34.09900  -33.67700 -19.41600 1.000 30.20362  ? 84  TYR A C    1 
ATOM   1269 O  O    . TYR A 1 84  ? 34.79500  -33.46300 -20.41100 1.000 28.05863  ? 84  TYR A O    1 
ATOM   1270 C  CB   . TYR A 1 84  ? 32.32800  -32.09100 -18.54800 1.000 27.71122  ? 84  TYR A CB   1 
ATOM   1271 C  CG   . TYR A 1 84  ? 33.23200  -30.90600 -18.77100 1.000 29.54038  ? 84  TYR A CG   1 
ATOM   1272 C  CD1  . TYR A 1 84  ? 33.59900  -30.51000 -20.03600 1.000 30.40628  ? 84  TYR A CD1  1 
ATOM   1273 C  CD2  . TYR A 1 84  ? 33.68600  -30.14100 -17.69300 1.000 29.62460  ? 84  TYR A CD2  1 
ATOM   1274 C  CE1  . TYR A 1 84  ? 34.41700  -29.40900 -20.22900 1.000 32.23808  ? 84  TYR A CE1  1 
ATOM   1275 C  CE2  . TYR A 1 84  ? 34.50300  -29.04700 -17.89200 1.000 30.55366  ? 84  TYR A CE2  1 
ATOM   1276 C  CZ   . TYR A 1 84  ? 34.86000  -28.68900 -19.15300 1.000 36.24119  ? 84  TYR A CZ   1 
ATOM   1277 O  OH   . TYR A 1 84  ? 35.66500  -27.59200 -19.31800 1.000 35.25949  ? 84  TYR A OH   1 
ATOM   1278 H  H    . TYR A 1 84  ? 31.42600  -34.30600 -18.16700 1.000 33.70000  ? 84  TYR A H    1 
ATOM   1279 H  HA   . TYR A 1 84  ? 32.36200  -33.12000 -20.32100 1.000 31.95000  ? 84  TYR A HA   1 
ATOM   1280 H  HB2  . TYR A 1 84  ? 31.42200  -31.79900 -18.73000 1.000 33.25000  ? 84  TYR A HB2  1 
ATOM   1281 H  HB3  . TYR A 1 84  ? 32.41300  -32.34400 -17.61500 1.000 33.25000  ? 84  TYR A HB3  1 
ATOM   1282 H  HD1  . TYR A 1 84  ? 33.29300  -30.98900 -20.77200 1.000 36.49000  ? 84  TYR A HD1  1 
ATOM   1283 H  HD2  . TYR A 1 84  ? 33.43300  -30.37200 -16.82900 1.000 35.55000  ? 84  TYR A HD2  1 
ATOM   1284 H  HE1  . TYR A 1 84  ? 34.66500  -29.16000 -21.09000 1.000 38.69000  ? 84  TYR A HE1  1 
ATOM   1285 H  HE2  . TYR A 1 84  ? 34.80900  -28.55600 -17.16400 1.000 36.66000  ? 84  TYR A HE2  1 
ATOM   1286 H  HH   . TYR A 1 84  ? 35.80700  -27.46100 -20.13600 1.000 42.31000  ? 84  TYR A HH   1 
ATOM   1287 N  N    . MET A 1 85  ? 34.60000  -34.26700 -18.33600 1.000 28.43762  ? 85  MET A N    1 
ATOM   1288 C  CA   . MET A 1 85  ? 36.01000  -34.59000 -18.33400 1.000 27.49277  ? 85  MET A CA   1 
ATOM   1289 C  C    . MET A 1 85  ? 36.34100  -35.67600 -19.34800 1.000 29.33510  ? 85  MET A C    1 
ATOM   1290 O  O    . MET A 1 85  ? 37.38300  -35.62100 -20.01200 1.000 29.09296  ? 85  MET A O    1 
ATOM   1291 C  CB   . MET A 1 85  ? 36.52300  -35.01600 -16.98400 1.000 30.71947  ? 85  MET A CB   1 
ATOM   1292 C  CG   . MET A 1 85  ? 36.43400  -33.96000 -15.93100 1.000 29.45880  ? 85  MET A CG   1 
ATOM   1293 S  SD   . MET A 1 85  ? 37.84500  -32.89400 -16.15900 1.000 33.01712  ? 85  MET A SD   1 
ATOM   1294 C  CE   . MET A 1 85  ? 37.24600  -31.48000 -16.89200 1.000 31.62484  ? 85  MET A CE   1 
ATOM   1295 H  H    . MET A 1 85  ? 34.16200  -34.47800 -17.62700 1.000 34.13000  ? 85  MET A H    1 
ATOM   1296 H  HA   . MET A 1 85  ? 36.46100  -33.76100 -18.55800 1.000 32.99000  ? 85  MET A HA   1 
ATOM   1297 H  HB2  . MET A 1 85  ? 36.00400  -35.77800 -16.68100 1.000 36.86000  ? 85  MET A HB2  1 
ATOM   1298 H  HB3  . MET A 1 85  ? 37.45600  -35.26500 -17.07100 1.000 36.86000  ? 85  MET A HB3  1 
ATOM   1299 H  HG2  . MET A 1 85  ? 35.61700  -33.44700 -16.03400 1.000 35.35000  ? 85  MET A HG2  1 
ATOM   1300 H  HG3  . MET A 1 85  ? 36.46600  -34.35800 -15.04700 1.000 35.35000  ? 85  MET A HG3  1 
ATOM   1301 H  HE1  . MET A 1 85  ? 37.98100  -30.86300 -17.03600 1.000 37.95000  ? 85  MET A HE1  1 
ATOM   1302 H  HE2  . MET A 1 85  ? 36.83700  -31.71200 -17.74000 1.000 37.95000  ? 85  MET A HE2  1 
ATOM   1303 H  HE3  . MET A 1 85  ? 36.58600  -31.07600 -16.30600 1.000 37.95000  ? 85  MET A HE3  1 
ATOM   1304 N  N    . SER A 1 86  ? 35.49100  -36.69100 -19.45200 1.000 29.91411  ? 86  SER A N    1 
ATOM   1305 C  CA   . SER A 1 86  ? 35.75400  -37.76300 -20.40500 1.000 29.08770  ? 86  SER A CA   1 
ATOM   1306 C  C    . SER A 1 86  ? 35.84700  -37.21900 -21.82200 1.000 29.80094  ? 86  SER A C    1 
ATOM   1307 O  O    . SER A 1 86  ? 36.73600  -37.61100 -22.58500 1.000 28.12179  ? 86  SER A O    1 
ATOM   1308 C  CB   . SER A 1 86  ? 34.67000  -38.82800 -20.30000 1.000 34.77259  ? 86  SER A CB   1 
ATOM   1309 O  OG   . SER A 1 86  ? 34.77900  -39.75600 -21.36100 1.000 39.06784  ? 86  SER A OG   1 
ATOM   1310 H  H    . SER A 1 86  ? 34.77000  -36.78200 -18.99200 1.000 35.90000  ? 86  SER A H    1 
ATOM   1311 H  HA   . SER A 1 86  ? 36.60200  -38.18200 -20.18900 1.000 34.91000  ? 86  SER A HA   1 
ATOM   1312 H  HB2  . SER A 1 86  ? 34.76800  -39.29800 -19.45700 1.000 41.73000  ? 86  SER A HB2  1 
ATOM   1313 H  HB3  . SER A 1 86  ? 33.80100  -38.40000 -20.34300 1.000 41.73000  ? 86  SER A HB3  1 
ATOM   1314 H  HG   . SER A 1 86  ? 34.18500  -40.34500 -21.28900 1.000 46.88000  ? 86  SER A HG   1 
ATOM   1315 N  N    . ALA A 1 87  ? 34.94800  -36.29400 -22.17700 1.000 27.81386  ? 87  ALA A N    1 
ATOM   1316 C  CA   . ALA A 1 87  ? 34.98300  -35.68500 -23.50900 1.000 25.62676  ? 87  ALA A CA   1 
ATOM   1317 C  C    . ALA A 1 87  ? 36.22000  -34.80400 -23.67000 1.000 29.05348  ? 87  ALA A C    1 
ATOM   1318 O  O    . ALA A 1 87  ? 36.89200  -34.84500 -24.70500 1.000 27.26380  ? 87  ALA A O    1 
ATOM   1319 C  CB   . ALA A 1 87  ? 33.70500  -34.87900 -23.73900 1.000 26.10313  ? 87  ALA A CB   1 
ATOM   1320 H  H    . ALA A 1 87  ? 34.31500  -36.00600 -21.67100 1.000 33.38000  ? 87  ALA A H    1 
ATOM   1321 H  HA   . ALA A 1 87  ? 35.02100  -36.38100 -24.18400 1.000 30.75000  ? 87  ALA A HA   1 
ATOM   1322 H  HB1  . ALA A 1 87  ? 33.73600  -34.48400 -24.62400 1.000 31.32000  ? 87  ALA A HB1  1 
ATOM   1323 H  HB2  . ALA A 1 87  ? 32.94000  -35.47100 -23.66700 1.000 31.32000  ? 87  ALA A HB2  1 
ATOM   1324 H  HB3  . ALA A 1 87  ? 33.64700  -34.18100 -23.06800 1.000 31.32000  ? 87  ALA A HB3  1 
ATOM   1325 N  N    . LEU A 1 88  ? 36.56400  -34.03800 -22.63600 1.000 28.90873  ? 88  LEU A N    1 
ATOM   1326 C  CA   . LEU A 1 88  ? 37.71400  -33.14300 -22.71500 1.000 28.36919  ? 88  LEU A CA   1 
ATOM   1327 C  C    . LEU A 1 88  ? 39.00400  -33.90100 -22.97800 1.000 28.71660  ? 88  LEU A C    1 
ATOM   1328 O  O    . LEU A 1 88  ? 39.88500  -33.41100 -23.69200 1.000 30.19836  ? 88  LEU A O    1 
ATOM   1329 C  CB   . LEU A 1 88  ? 37.83000  -32.34000 -21.41100 1.000 28.54553  ? 88  LEU A CB   1 
ATOM   1330 C  CG   . LEU A 1 88  ? 38.94000  -31.29700 -21.34200 1.000 31.75907  ? 88  LEU A CG   1 
ATOM   1331 C  CD1  . LEU A 1 88  ? 38.78800  -30.25200 -22.40700 1.000 31.89330  ? 88  LEU A CD1  1 
ATOM   1332 C  CD2  . LEU A 1 88  ? 39.01700  -30.64600 -19.96100 1.000 30.87475  ? 88  LEU A CD2  1 
ATOM   1333 H  H    . LEU A 1 88  ? 36.15100  -34.01800 -21.88200 1.000 34.69000  ? 88  LEU A H    1 
ATOM   1334 H  HA   . LEU A 1 88  ? 37.57700  -32.52900 -23.45300 1.000 34.04000  ? 88  LEU A HA   1 
ATOM   1335 H  HB2  . LEU A 1 88  ? 36.99200  -31.87100 -21.27300 1.000 34.25000  ? 88  LEU A HB2  1 
ATOM   1336 H  HB3  . LEU A 1 88  ? 37.98300  -32.96600 -20.68600 1.000 34.25000  ? 88  LEU A HB3  1 
ATOM   1337 H  HG   . LEU A 1 88  ? 39.78000  -31.75700 -21.49900 1.000 38.11000  ? 88  LEU A HG   1 
ATOM   1338 H  HD11 . LEU A 1 88  ? 39.47400  -29.57600 -22.28700 1.000 38.27000  ? 88  LEU A HD11 1 
ATOM   1339 H  HD12 . LEU A 1 88  ? 38.88400  -30.67100 -23.27700 1.000 38.27000  ? 88  LEU A HD12 1 
ATOM   1340 H  HD13 . LEU A 1 88  ? 37.90900  -29.84800 -22.33000 1.000 38.27000  ? 88  LEU A HD13 1 
ATOM   1341 H  HD21 . LEU A 1 88  ? 39.73800  -29.99700 -19.95700 1.000 37.05000  ? 88  LEU A HD21 1 
ATOM   1342 H  HD22 . LEU A 1 88  ? 38.17400  -30.20600 -19.77200 1.000 37.05000  ? 88  LEU A HD22 1 
ATOM   1343 H  HD23 . LEU A 1 88  ? 39.18700  -31.33300 -19.29700 1.000 37.05000  ? 88  LEU A HD23 1 
ATOM   1344 N  N    . ASN A 1 89  ? 39.16900  -35.08100 -22.36800 1.000 28.92452  ? 89  ASN A N    1 
ATOM   1345 C  CA   . ASN A 1 89  ? 40.39600  -35.82800 -22.60700 1.000 29.00611  ? 89  ASN A CA   1 
ATOM   1346 C  C    . ASN A 1 89  ? 40.60400  -36.05600 -24.09300 1.000 30.08519  ? 89  ASN A C    1 
ATOM   1347 O  O    . ASN A 1 89  ? 41.74800  -36.12200 -24.54800 1.000 30.93529  ? 89  ASN A O    1 
ATOM   1348 C  CB   . ASN A 1 89  ? 40.39200  -37.15900 -21.86600 1.000 33.86722  ? 89  ASN A CB   1 
ATOM   1349 C  CG   . ASN A 1 89  ? 41.79300  -37.59600 -21.46200 1.000 37.10708  ? 89  ASN A CG   1 
ATOM   1350 O  OD1  . ASN A 1 89  ? 42.61600  -36.78500 -21.02800 1.000 38.82834  ? 89  ASN A OD1  1 
ATOM   1351 N  ND2  . ASN A 1 89  ? 42.07300  -38.88000 -21.61400 1.000 42.76829  ? 89  ASN A ND2  1 
ATOM   1352 H  H    . ASN A 1 89  ? 38.60600  -35.45100 -21.83300 1.000 34.71000  ? 89  ASN A H    1 
ATOM   1353 H  HA   . ASN A 1 89  ? 41.14100  -35.31600 -22.25600 1.000 34.81000  ? 89  ASN A HA   1 
ATOM   1354 H  HB2  . ASN A 1 89  ? 39.85800  -37.07400 -21.06100 1.000 40.64000  ? 89  ASN A HB2  1 
ATOM   1355 H  HB3  . ASN A 1 89  ? 40.01600  -37.84300 -22.44200 1.000 40.64000  ? 89  ASN A HB3  1 
ATOM   1356 H  HD21 . ASN A 1 89  ? 42.85100  -39.17900 -21.40100 1.000 51.32000  ? 89  ASN A HD21 1 
ATOM   1357 H  HD22 . ASN A 1 89  ? 41.47800  -39.41700 -21.92500 1.000 51.32000  ? 89  ASN A HD22 1 
ATOM   1358 N  N    . HIS A 1 90  ? 39.50900  -36.14400 -24.86200 1.000 29.56407  ? 90  HIS A N    1 
ATOM   1359 C  CA   . HIS A 1 90  ? 39.59100  -36.28900 -26.31000 1.000 28.80345  ? 90  HIS A CA   1 
ATOM   1360 C  C    . HIS A 1 90  ? 39.69400  -34.95000 -27.02500 1.000 29.59039  ? 90  HIS A C    1 
ATOM   1361 O  O    . HIS A 1 90  ? 40.54800  -34.77200 -27.89700 1.000 33.03291  ? 90  HIS A O    1 
ATOM   1362 C  CB   . HIS A 1 90  ? 38.35400  -37.01400 -26.86800 1.000 28.26918  ? 90  HIS A CB   1 
ATOM   1363 C  CG   . HIS A 1 90  ? 38.19700  -38.41900 -26.38500 1.000 31.61695  ? 90  HIS A CG   1 
ATOM   1364 N  ND1  . HIS A 1 90  ? 38.73800  -39.49800 -27.06000 1.000 35.60427  ? 90  HIS A ND1  1 
ATOM   1365 C  CD2  . HIS A 1 90  ? 37.50700  -38.93400 -25.34000 1.000 33.21714  ? 90  HIS A CD2  1 
ATOM   1366 C  CE1  . HIS A 1 90  ? 38.43100  -40.61100 -26.41500 1.000 39.20207  ? 90  HIS A CE1  1 
ATOM   1367 N  NE2  . HIS A 1 90  ? 37.67900  -40.29700 -25.37200 1.000 36.90442  ? 90  HIS A NE2  1 
ATOM   1368 H  H    . HIS A 1 90  ? 38.70400  -36.12100 -24.56000 1.000 35.48000  ? 90  HIS A H    1 
ATOM   1369 H  HA   . HIS A 1 90  ? 40.38200  -36.82000 -26.49000 1.000 34.56000  ? 90  HIS A HA   1 
ATOM   1370 H  HB2  . HIS A 1 90  ? 37.56100  -36.52200 -26.60300 1.000 33.92000  ? 90  HIS A HB2  1 
ATOM   1371 H  HB3  . HIS A 1 90  ? 38.42000  -37.04100 -27.83500 1.000 33.92000  ? 90  HIS A HB3  1 
ATOM   1372 H  HD2  . HIS A 1 90  ? 37.01000  -38.45500 -24.71700 1.000 39.86000  ? 90  HIS A HD2  1 
ATOM   1373 H  HE1  . HIS A 1 90  ? 38.69700  -41.46900 -26.65400 1.000 47.04000  ? 90  HIS A HE1  1 
ATOM   1374 H  HE2  . HIS A 1 90  ? 37.35200  -40.85500 -24.80600 1.000 44.29000  ? 90  HIS A HE2  1 
ATOM   1375 N  N    . THR A 1 91  ? 38.80500  -34.01400 -26.68900 1.000 28.76398  ? 91  THR A N    1 
ATOM   1376 C  CA   . THR A 1 91  ? 38.72800  -32.77100 -27.44000 1.000 26.64530  ? 91  THR A CA   1 
ATOM   1377 C  C    . THR A 1 91  ? 39.97400  -31.91700 -27.25100 1.000 28.77977  ? 91  THR A C    1 
ATOM   1378 O  O    . THR A 1 91  ? 40.28600  -31.10400 -28.12500 1.000 30.63788  ? 91  THR A O    1 
ATOM   1379 C  CB   . THR A 1 91  ? 37.49200  -31.93100 -27.09700 1.000 26.69267  ? 91  THR A CB   1 
ATOM   1380 O  OG1  . THR A 1 91  ? 37.57000  -31.43600 -25.74400 1.000 27.13220  ? 91  THR A OG1  1 
ATOM   1381 C  CG2  . THR A 1 91  ? 36.19900  -32.73400 -27.28100 1.000 26.45054  ? 91  THR A CG2  1 
ATOM   1382 H  H    . THR A 1 91  ? 38.24500  -34.07800 -26.04000 1.000 34.52000  ? 91  THR A H    1 
ATOM   1383 H  HA   . THR A 1 91  ? 38.63300  -33.01900 -28.37300 1.000 31.97000  ? 91  THR A HA   1 
ATOM   1384 H  HB   . THR A 1 91  ? 37.46000  -31.17600 -27.70500 1.000 32.03000  ? 91  THR A HB   1 
ATOM   1385 H  HG1  . THR A 1 91  ? 36.91500  -30.93500 -25.58300 1.000 32.56000  ? 91  THR A HG1  1 
ATOM   1386 H  HG21 . THR A 1 91  ? 35.43000  -32.17300 -27.09500 1.000 31.74000  ? 91  THR A HG21 1 
ATOM   1387 H  HG22 . THR A 1 91  ? 36.13700  -33.05900 -28.19300 1.000 31.74000  ? 91  THR A HG22 1 
ATOM   1388 H  HG23 . THR A 1 91  ? 36.19000  -33.49200 -26.67600 1.000 31.74000  ? 91  THR A HG23 1 
ATOM   1389 N  N    . LYS A 1 92  ? 40.70200  -32.08200 -26.14900 1.000 30.40365  ? 92  LYS A N    1 
ATOM   1390 C  CA   . LYS A 1 92  ? 41.94300  -31.33400 -26.01500 1.000 33.25399  ? 92  LYS A CA   1 
ATOM   1391 C  C    . LYS A 1 92  ? 42.98900  -31.78100 -27.02500 1.000 35.99116  ? 92  LYS A C    1 
ATOM   1392 O  O    . LYS A 1 92  ? 43.95400  -31.04300 -27.24900 1.000 38.79939  ? 92  LYS A O    1 
ATOM   1393 C  CB   . LYS A 1 92  ? 42.44500  -31.43100 -24.57100 1.000 35.75429  ? 92  LYS A CB   1 
ATOM   1394 C  CG   . LYS A 1 92  ? 43.29300  -32.61000 -24.26800 1.000 39.48105  ? 92  LYS A CG   1 
ATOM   1395 C  CD   . LYS A 1 92  ? 43.46900  -32.78000 -22.73700 1.000 47.61360  ? 92  LYS A CD   1 
ATOM   1396 C  CE   . LYS A 1 92  ? 44.16500  -34.10200 -22.44000 1.000 50.00073  ? 92  LYS A CE   1 
ATOM   1397 N  NZ   . LYS A 1 92  ? 44.36000  -34.35400 -20.97500 1.000 43.81841  ? 92  LYS A NZ   1 
ATOM   1398 H  H    . LYS A 1 92  ? 40.50500  -32.60200 -25.49200 1.000 36.48000  ? 92  LYS A H    1 
ATOM   1399 H  HA   . LYS A 1 92  ? 41.79000  -30.39100 -26.18200 1.000 39.91000  ? 92  LYS A HA   1 
ATOM   1400 H  HB2  . LYS A 1 92  ? 42.97200  -30.64000 -24.37700 1.000 42.91000  ? 92  LYS A HB2  1 
ATOM   1401 H  HB3  . LYS A 1 92  ? 41.67600  -31.47000 -23.98200 1.000 42.91000  ? 92  LYS A HB3  1 
ATOM   1402 H  HG2  . LYS A 1 92  ? 42.87300  -33.41100 -24.62100 1.000 47.38000  ? 92  LYS A HG2  1 
ATOM   1403 H  HG3  . LYS A 1 92  ? 44.16900  -32.49100 -24.66800 1.000 47.38000  ? 92  LYS A HG3  1 
ATOM   1404 H  HD2  . LYS A 1 92  ? 44.01200  -32.05700 -22.38800 1.000 57.14000  ? 92  LYS A HD2  1 
ATOM   1405 H  HD3  . LYS A 1 92  ? 42.60100  -32.78200 -22.30600 1.000 57.14000  ? 92  LYS A HD3  1 
ATOM   1406 H  HE2  . LYS A 1 92  ? 43.62900  -34.82600 -22.79800 1.000 60.00000  ? 92  LYS A HE2  1 
ATOM   1407 H  HE3  . LYS A 1 92  ? 45.03900  -34.09700 -22.86000 1.000 60.00000  ? 92  LYS A HE3  1 
ATOM   1408 H  HZ1  . LYS A 1 92  ? 44.85800  -33.70800 -20.61900 1.000 52.58000  ? 92  LYS A HZ1  1 
ATOM   1409 H  HZ2  . LYS A 1 92  ? 43.57200  -34.37400 -20.56200 1.000 52.58000  ? 92  LYS A HZ2  1 
ATOM   1410 H  HZ3  . LYS A 1 92  ? 44.77000  -35.13500 -20.85300 1.000 52.58000  ? 92  LYS A HZ3  1 
ATOM   1411 N  N    . LYS A 1 93  ? 42.79200  -32.93100 -27.68500 1.000 33.99881  ? 93  LYS A N    1 
ATOM   1412 C  CA   . LYS A 1 93  ? 43.70900  -33.41200 -28.70900 1.000 33.49612  ? 93  LYS A CA   1 
ATOM   1413 C  C    . LYS A 1 93  ? 43.19000  -33.17600 -30.12200 1.000 33.90933  ? 93  LYS A C    1 
ATOM   1414 O  O    . LYS A 1 93  ? 43.92600  -33.40600 -31.08800 1.000 37.00970  ? 93  LYS A O    1 
ATOM   1415 C  CB   . LYS A 1 93  ? 44.00300  -34.91000 -28.52400 1.000 40.11534  ? 93  LYS A CB   1 
ATOM   1416 C  CG   . LYS A 1 93  ? 44.74700  -35.25600 -27.23000 1.000 43.48416  ? 93  LYS A CG   1 
ATOM   1417 C  CD   . LYS A 1 93  ? 44.92500  -36.77900 -26.99300 1.000 65.06833  ? 93  LYS A CD   1 
ATOM   1418 C  CE   . LYS A 1 93  ? 43.62600  -37.58100 -26.84200 1.000 66.95013  ? 93  LYS A CE   1 
ATOM   1419 N  NZ   . LYS A 1 93  ? 43.39100  -38.01900 -25.42000 1.000 63.74712  ? 93  LYS A NZ   1 
ATOM   1420 H  H    . LYS A 1 93  ? 42.12100  -33.45200 -27.55000 1.000 40.80000  ? 93  LYS A H    1 
ATOM   1421 H  HA   . LYS A 1 93  ? 44.55000  -32.93900 -28.60900 1.000 40.20000  ? 93  LYS A HA   1 
ATOM   1422 H  HB2  . LYS A 1 93  ? 43.16000  -35.39100 -28.51500 1.000 48.14000  ? 93  LYS A HB2  1 
ATOM   1423 H  HB3  . LYS A 1 93  ? 44.54900  -35.21100 -29.26600 1.000 48.14000  ? 93  LYS A HB3  1 
ATOM   1424 H  HG2  . LYS A 1 93  ? 45.63100  -34.85800 -27.26300 1.000 52.18000  ? 93  LYS A HG2  1 
ATOM   1425 H  HG3  . LYS A 1 93  ? 44.24900  -34.89800 -26.47900 1.000 52.18000  ? 93  LYS A HG3  1 
ATOM   1426 H  HD2  . LYS A 1 93  ? 45.40700  -37.15200 -27.74700 1.000 78.08000  ? 93  LYS A HD2  1 
ATOM   1427 H  HD3  . LYS A 1 93  ? 45.43600  -36.90400 -26.17800 1.000 78.08000  ? 93  LYS A HD3  1 
ATOM   1428 H  HE2  . LYS A 1 93  ? 42.87700  -37.02900 -27.11600 1.000 80.34000  ? 93  LYS A HE2  1 
ATOM   1429 H  HE3  . LYS A 1 93  ? 43.67500  -38.37400 -27.39800 1.000 80.34000  ? 93  LYS A HE3  1 
ATOM   1430 H  HZ1  . LYS A 1 93  ? 42.64400  -38.50100 -25.36900 1.000 76.50000  ? 93  LYS A HZ1  1 
ATOM   1431 H  HZ2  . LYS A 1 93  ? 44.07400  -38.51500 -25.13700 1.000 76.50000  ? 93  LYS A HZ2  1 
ATOM   1432 H  HZ3  . LYS A 1 93  ? 43.31200  -37.30800 -24.89100 1.000 76.50000  ? 93  LYS A HZ3  1 
ATOM   1433 N  N    . TRP A 1 94  ? 41.94600  -32.73800 -30.26100 1.000 30.30363  ? 94  TRP A N    1 
ATOM   1434 C  CA   . TRP A 1 94  ? 41.44700  -32.29700 -31.55500 1.000 31.71959  ? 94  TRP A CA   1 
ATOM   1435 C  C    . TRP A 1 94  ? 42.19200  -31.04100 -32.00200 1.000 32.99080  ? 94  TRP A C    1 
ATOM   1436 O  O    . TRP A 1 94  ? 42.78400  -30.31700 -31.19200 1.000 32.49337  ? 94  TRP A O    1 
ATOM   1437 C  CB   . TRP A 1 94  ? 39.96200  -31.98400 -31.46700 1.000 29.79305  ? 94  TRP A CB   1 
ATOM   1438 C  CG   . TRP A 1 94  ? 39.04300  -33.15700 -31.32100 1.000 29.04822  ? 94  TRP A CG   1 
ATOM   1439 C  CD1  . TRP A 1 94  ? 39.37600  -34.48500 -31.34100 1.000 29.64829  ? 94  TRP A CD1  1 
ATOM   1440 C  CD2  . TRP A 1 94  ? 37.62000  -33.09900 -31.16600 1.000 26.52423  ? 94  TRP A CD2  1 
ATOM   1441 N  NE1  . TRP A 1 94  ? 38.24200  -35.25400 -31.20900 1.000 30.04834  ? 94  TRP A NE1  1 
ATOM   1442 C  CE2  . TRP A 1 94  ? 37.15200  -34.42600 -31.10100 1.000 26.21104  ? 94  TRP A CE2  1 
ATOM   1443 C  CE3  . TRP A 1 94  ? 36.69500  -32.05500 -31.10700 1.000 25.56096  ? 94  TRP A CE3  1 
ATOM   1444 C  CZ2  . TRP A 1 94  ? 35.80400  -34.72700 -30.97200 1.000 25.49516  ? 94  TRP A CZ2  1 
ATOM   1445 C  CZ3  . TRP A 1 94  ? 35.35500  -32.35300 -30.95900 1.000 26.40053  ? 94  TRP A CZ3  1 
ATOM   1446 C  CH2  . TRP A 1 94  ? 34.92000  -33.67200 -30.88700 1.000 26.19261  ? 94  TRP A CH2  1 
ATOM   1447 H  H    . TRP A 1 94  ? 41.37100  -32.68600 -29.62300 1.000 36.36000  ? 94  TRP A H    1 
ATOM   1448 H  HA   . TRP A 1 94  ? 41.58200  -32.99900 -32.21100 1.000 38.06000  ? 94  TRP A HA   1 
ATOM   1449 H  HB2  . TRP A 1 94  ? 39.81900  -31.41200 -30.69700 1.000 35.75000  ? 94  TRP A HB2  1 
ATOM   1450 H  HB3  . TRP A 1 94  ? 39.70300  -31.51900 -32.27800 1.000 35.75000  ? 94  TRP A HB3  1 
ATOM   1451 H  HD1  . TRP A 1 94  ? 40.24000  -34.81800 -31.43000 1.000 35.58000  ? 94  TRP A HD1  1 
ATOM   1452 H  HE1  . TRP A 1 94  ? 38.22000  -36.11300 -31.19600 1.000 36.06000  ? 94  TRP A HE1  1 
ATOM   1453 H  HE3  . TRP A 1 94  ? 36.97800  -31.17100 -31.16800 1.000 30.67000  ? 94  TRP A HE3  1 
ATOM   1454 H  HZ2  . TRP A 1 94  ? 35.50700  -35.60800 -30.94400 1.000 30.59000  ? 94  TRP A HZ2  1 
ATOM   1455 H  HZ3  . TRP A 1 94  ? 34.73500  -31.66200 -30.90600 1.000 31.68000  ? 94  TRP A HZ3  1 
ATOM   1456 H  HH2  . TRP A 1 94  ? 34.01200  -33.84600 -30.77900 1.000 31.43000  ? 94  TRP A HH2  1 
ATOM   1457 N  N    . LYS A 1 95  ? 42.13500  -30.76100 -33.30500 1.000 30.73790  ? 95  LYS A N    1 
ATOM   1458 C  CA   . LYS A 1 95  ? 42.69400  -29.54200 -33.87400 1.000 33.87248  ? 95  LYS A CA   1 
ATOM   1459 C  C    . LYS A 1 95  ? 41.57800  -28.56700 -34.25000 1.000 31.36429  ? 95  LYS A C    1 
ATOM   1460 O  O    . LYS A 1 95  ? 40.50300  -28.97400 -34.70300 1.000 32.00384  ? 95  LYS A O    1 
ATOM   1461 C  CB   . LYS A 1 95  ? 43.53300  -29.86500 -35.10700 1.000 32.68550  ? 95  LYS A CB   1 
ATOM   1462 C  CG   . LYS A 1 95  ? 44.79400  -30.69100 -34.86100 1.000 37.68610  ? 95  LYS A CG   1 
ATOM   1463 C  CD   . LYS A 1 95  ? 45.48900  -30.31700 -33.58200 1.000 44.89222  ? 95  LYS A CD   1 
ATOM   1464 C  CE   . LYS A 1 95  ? 46.96800  -30.69300 -33.59000 1.000 61.00731  ? 95  LYS A CE   1 
ATOM   1465 N  NZ   . LYS A 1 95  ? 47.81200  -29.62700 -32.95500 1.000 72.89821  ? 95  LYS A NZ   1 
ATOM   1466 H  H    . LYS A 1 95  ? 41.76900  -31.27500 -33.88900 1.000 36.88000  ? 95  LYS A H    1 
ATOM   1467 H  HA   . LYS A 1 95  ? 43.25700  -29.10700 -33.21400 1.000 40.65000  ? 95  LYS A HA   1 
ATOM   1468 H  HB2  . LYS A 1 95  ? 42.98000  -30.36400 -35.72800 1.000 39.22000  ? 95  LYS A HB2  1 
ATOM   1469 H  HB3  . LYS A 1 95  ? 43.81300  -29.02800 -35.51100 1.000 39.22000  ? 95  LYS A HB3  1 
ATOM   1470 H  HG2  . LYS A 1 95  ? 44.55300  -31.62900 -34.80900 1.000 45.22000  ? 95  LYS A HG2  1 
ATOM   1471 H  HG3  . LYS A 1 95  ? 45.41400  -30.54800 -35.59300 1.000 45.22000  ? 95  LYS A HG3  1 
ATOM   1472 H  HD2  . LYS A 1 95  ? 45.42400  -29.35800 -33.45400 1.000 53.87000  ? 95  LYS A HD2  1 
ATOM   1473 H  HD3  . LYS A 1 95  ? 45.06500  -30.78100 -32.84300 1.000 53.87000  ? 95  LYS A HD3  1 
ATOM   1474 H  HE2  . LYS A 1 95  ? 47.09200  -31.51600 -33.09200 1.000 73.21000  ? 95  LYS A HE2  1 
ATOM   1475 H  HE3  . LYS A 1 95  ? 47.26400  -30.81100 -34.50600 1.000 73.21000  ? 95  LYS A HE3  1 
ATOM   1476 H  HZ1  . LYS A 1 95  ? 48.66800  -29.87400 -32.96000 1.000 87.48000  ? 95  LYS A HZ1  1 
ATOM   1477 H  HZ2  . LYS A 1 95  ? 47.72900  -28.86400 -33.40600 1.000 87.48000  ? 95  LYS A HZ2  1 
ATOM   1478 H  HZ3  . LYS A 1 95  ? 47.55500  -29.49500 -32.11300 1.000 87.48000  ? 95  LYS A HZ3  1 
ATOM   1479 N  N    . TYR A 1 96  ? 41.84400  -27.27400 -34.07600 1.000 31.36429  ? 96  TYR A N    1 
ATOM   1480 C  CA   . TYR A 1 96  ? 40.84900  -26.21900 -34.27800 1.000 31.64327  ? 96  TYR A CA   1 
ATOM   1481 C  C    . TYR A 1 96  ? 41.40900  -25.20100 -35.25500 1.000 32.42494  ? 96  TYR A C    1 
ATOM   1482 O  O    . TYR A 1 96  ? 41.83700  -24.10800 -34.86600 1.000 33.21451  ? 96  TYR A O    1 
ATOM   1483 C  CB   . TYR A 1 96  ? 40.48500  -25.57200 -32.94000 1.000 30.42996  ? 96  TYR A CB   1 
ATOM   1484 C  CG   . TYR A 1 96  ? 39.94500  -26.60900 -31.97900 1.000 29.77199  ? 96  TYR A CG   1 
ATOM   1485 C  CD1  . TYR A 1 96  ? 38.64600  -27.08300 -32.10500 1.000 30.31416  ? 96  TYR A CD1  1 
ATOM   1486 C  CD2  . TYR A 1 96  ? 40.75100  -27.15800 -30.99200 1.000 29.93517  ? 96  TYR A CD2  1 
ATOM   1487 C  CE1  . TYR A 1 96  ? 38.14800  -28.05400 -31.27100 1.000 27.70595  ? 96  TYR A CE1  1 
ATOM   1488 C  CE2  . TYR A 1 96  ? 40.26000  -28.13500 -30.13800 1.000 31.19848  ? 96  TYR A CE2  1 
ATOM   1489 C  CZ   . TYR A 1 96  ? 38.95700  -28.57500 -30.28200 1.000 29.84832  ? 96  TYR A CZ   1 
ATOM   1490 O  OH   . TYR A 1 96  ? 38.43700  -29.55500 -29.47000 1.000 28.85872  ? 96  TYR A OH   1 
ATOM   1491 H  H    . TYR A 1 96  ? 42.61300  -26.97500 -33.83500 1.000 37.64000  ? 96  TYR A H    1 
ATOM   1492 H  HA   . TYR A 1 96  ? 40.04300  -26.59200 -34.66700 1.000 37.97000  ? 96  TYR A HA   1 
ATOM   1493 H  HB2  . TYR A 1 96  ? 41.27600  -25.17000 -32.54900 1.000 36.51000  ? 96  TYR A HB2  1 
ATOM   1494 H  HB3  . TYR A 1 96  ? 39.80400  -24.89600 -33.08100 1.000 36.51000  ? 96  TYR A HB3  1 
ATOM   1495 H  HD1  . TYR A 1 96  ? 38.09900  -26.73400 -32.77200 1.000 36.38000  ? 96  TYR A HD1  1 
ATOM   1496 H  HD2  . TYR A 1 96  ? 41.63000  -26.86800 -30.90200 1.000 35.92000  ? 96  TYR A HD2  1 
ATOM   1497 H  HE1  . TYR A 1 96  ? 37.27500  -28.35700 -31.37100 1.000 33.25000  ? 96  TYR A HE1  1 
ATOM   1498 H  HE2  . TYR A 1 96  ? 40.80300  -28.49300 -29.47400 1.000 37.44000  ? 96  TYR A HE2  1 
ATOM   1499 H  HH   . TYR A 1 96  ? 39.02900  -29.83800 -28.94500 1.000 34.63000  ? 96  TYR A HH   1 
ATOM   1500 N  N    . PRO A 1 97  ? 41.47200  -25.55100 -36.53500 1.000 31.73802  ? 97  PRO A N    1 
ATOM   1501 C  CA   . PRO A 1 97  ? 42.00900  -24.60400 -37.51300 1.000 30.40891  ? 97  PRO A CA   1 
ATOM   1502 C  C    . PRO A 1 97  ? 41.09100  -23.40900 -37.68800 1.000 28.71397  ? 97  PRO A C    1 
ATOM   1503 O  O    . PRO A 1 97  ? 39.86600  -23.51600 -37.59600 1.000 29.61671  ? 97  PRO A O    1 
ATOM   1504 C  CB   . PRO A 1 97  ? 42.10300  -25.43000 -38.80800 1.000 31.20374  ? 97  PRO A CB   1 
ATOM   1505 C  CG   . PRO A 1 97  ? 41.05900  -26.47200 -38.65900 1.000 31.46430  ? 97  PRO A CG   1 
ATOM   1506 C  CD   . PRO A 1 97  ? 41.00300  -26.80000 -37.16200 1.000 31.06162  ? 97  PRO A CD   1 
ATOM   1507 H  HA   . PRO A 1 97  ? 42.89500  -24.30500 -37.25400 1.000 36.49000  ? 97  PRO A HA   1 
ATOM   1508 H  HB2  . PRO A 1 97  ? 41.92500  -24.86500 -39.57600 1.000 37.44000  ? 97  PRO A HB2  1 
ATOM   1509 H  HB3  . PRO A 1 97  ? 42.98400  -25.82800 -38.88500 1.000 37.44000  ? 97  PRO A HB3  1 
ATOM   1510 H  HG2  . PRO A 1 97  ? 40.20600  -26.12800 -38.96700 1.000 37.76000  ? 97  PRO A HG2  1 
ATOM   1511 H  HG3  . PRO A 1 97  ? 41.30500  -27.25700 -39.17300 1.000 37.76000  ? 97  PRO A HG3  1 
ATOM   1512 H  HD2  . PRO A 1 97  ? 40.09700  -27.00700 -36.88600 1.000 37.27000  ? 97  PRO A HD2  1 
ATOM   1513 H  HD3  . PRO A 1 97  ? 41.59300  -27.53900 -36.94600 1.000 37.27000  ? 97  PRO A HD3  1 
ATOM   1514 N  N    . GLN A 1 98  ? 41.71200  -22.25800 -37.94800 1.000 31.87224  ? 98  GLN A N    1 
ATOM   1515 C  CA   . GLN A 1 98  ? 40.98600  -21.06400 -38.35200 1.000 31.33007  ? 98  GLN A CA   1 
ATOM   1516 C  C    . GLN A 1 98  ? 40.68400  -21.15400 -39.84300 1.000 29.25351  ? 98  GLN A C    1 
ATOM   1517 O  O    . GLN A 1 98  ? 41.61300  -21.15500 -40.65900 1.000 34.37254  ? 98  GLN A O    1 
ATOM   1518 C  CB   . GLN A 1 98  ? 41.81500  -19.81400 -38.07400 1.000 32.73287  ? 98  GLN A CB   1 
ATOM   1519 C  CG   . GLN A 1 98  ? 42.00900  -19.51900 -36.60100 1.000 34.56467  ? 98  GLN A CG   1 
ATOM   1520 C  CD   . GLN A 1 98  ? 40.70200  -19.26900 -35.89700 1.000 37.26236  ? 98  GLN A CD   1 
ATOM   1521 O  OE1  . GLN A 1 98  ? 39.93200  -18.38600 -36.28500 1.000 36.18329  ? 98  GLN A OE1  1 
ATOM   1522 N  NE2  . GLN A 1 98  ? 40.45000  -20.02900 -34.85200 1.000 33.12766  ? 98  GLN A NE2  1 
ATOM   1523 H  H    . GLN A 1 98  ? 42.56300  -22.14600 -37.89600 1.000 38.25000  ? 98  GLN A H    1 
ATOM   1524 H  HA   . GLN A 1 98  ? 40.15800  -21.00600 -37.85100 1.000 37.60000  ? 98  GLN A HA   1 
ATOM   1525 H  HB2  . GLN A 1 98  ? 42.69300  -19.92800 -38.47000 1.000 39.28000  ? 98  GLN A HB2  1 
ATOM   1526 H  HB3  . GLN A 1 98  ? 41.36900  -19.05000 -38.47200 1.000 39.28000  ? 98  GLN A HB3  1 
ATOM   1527 H  HG2  . GLN A 1 98  ? 42.44000  -20.27800 -36.17800 1.000 41.48000  ? 98  GLN A HG2  1 
ATOM   1528 H  HG3  . GLN A 1 98  ? 42.56100  -18.72700 -36.50400 1.000 41.48000  ? 98  GLN A HG3  1 
ATOM   1529 H  HE21 . GLN A 1 98  ? 41.01800  -20.62600 -34.60700 1.000 39.76000  ? 98  GLN A HE21 1 
ATOM   1530 H  HE22 . GLN A 1 98  ? 39.71700  -19.92800 -34.41400 1.000 39.76000  ? 98  GLN A HE22 1 
ATOM   1531 N  N    . VAL A 1 99  ? 39.40600  -21.23700 -40.20100 1.000 29.14297  ? 99  VAL A N    1 
ATOM   1532 C  CA   . VAL A 1 99  ? 38.98800  -21.36300 -41.60000 1.000 27.05324  ? 99  VAL A CA   1 
ATOM   1533 C  C    . VAL A 1 99  ? 38.12500  -20.16100 -41.94600 1.000 30.57209  ? 99  VAL A C    1 
ATOM   1534 O  O    . VAL A 1 99  ? 37.05900  -19.96600 -41.35500 1.000 30.92213  ? 99  VAL A O    1 
ATOM   1535 C  CB   . VAL A 1 99  ? 38.22100  -22.67100 -41.83600 1.000 26.96376  ? 99  VAL A CB   1 
ATOM   1536 C  CG1  . VAL A 1 99  ? 37.83000  -22.80100 -43.29600 1.000 29.09559  ? 99  VAL A CG1  1 
ATOM   1537 C  CG2  . VAL A 1 99  ? 39.06500  -23.85300 -41.41100 1.000 28.65080  ? 99  VAL A CG2  1 
ATOM   1538 H  H    . VAL A 1 99  ? 38.75100  -21.22200 -39.64400 1.000 34.97000  ? 99  VAL A H    1 
ATOM   1539 H  HA   . VAL A 1 99  ? 39.76900  -21.34900 -42.17500 1.000 32.46000  ? 99  VAL A HA   1 
ATOM   1540 H  HB   . VAL A 1 99  ? 37.41000  -22.66200 -41.30300 1.000 32.36000  ? 99  VAL A HB   1 
ATOM   1541 H  HG11 . VAL A 1 99  ? 37.47000  -23.68800 -43.44900 1.000 34.91000  ? 99  VAL A HG11 1 
ATOM   1542 H  HG12 . VAL A 1 99  ? 37.16000  -22.13100 -43.50500 1.000 34.91000  ? 99  VAL A HG12 1 
ATOM   1543 H  HG13 . VAL A 1 99  ? 38.61700  -22.66400 -43.84700 1.000 34.91000  ? 99  VAL A HG13 1 
ATOM   1544 H  HG21 . VAL A 1 99  ? 38.59600  -24.67200 -41.63600 1.000 34.38000  ? 99  VAL A HG21 1 
ATOM   1545 H  HG22 . VAL A 1 99  ? 39.91400  -23.81900 -41.87900 1.000 34.38000  ? 99  VAL A HG22 1 
ATOM   1546 H  HG23 . VAL A 1 99  ? 39.21300  -23.80800 -40.45400 1.000 34.38000  ? 99  VAL A HG23 1 
ATOM   1547 N  N    . ASN A 1 100 ? 38.56500  -19.37700 -42.92300 1.000 30.38259  ? 100 ASN A N    1 
ATOM   1548 C  CA   . ASN A 1 100 ? 37.85800  -18.15500 -43.30400 1.000 31.34323  ? 100 ASN A CA   1 
ATOM   1549 C  C    . ASN A 1 100 ? 37.52200  -17.27400 -42.10700 1.000 33.95144  ? 100 ASN A C    1 
ATOM   1550 O  O    . ASN A 1 100 ? 36.43300  -16.69300 -42.02800 1.000 34.02513  ? 100 ASN A O    1 
ATOM   1551 C  CB   . ASN A 1 100 ? 36.57100  -18.44200 -44.06800 1.000 31.43535  ? 100 ASN A CB   1 
ATOM   1552 C  CG   . ASN A 1 100 ? 36.15300  -17.27000 -44.93700 1.000 37.24657  ? 100 ASN A CG   1 
ATOM   1553 O  OD1  . ASN A 1 100 ? 36.97000  -16.68900 -45.63800 1.000 38.84413  ? 100 ASN A OD1  1 
ATOM   1554 N  ND2  . ASN A 1 100 ? 34.88800  -16.88200 -44.84200 1.000 36.99917  ? 100 ASN A ND2  1 
ATOM   1555 H  H    . ASN A 1 100 ? 39.27500  -19.52900 -43.38400 1.000 36.46000  ? 100 ASN A H    1 
ATOM   1556 H  HA   . ASN A 1 100 ? 38.47200  -17.67400 -43.88100 1.000 37.61000  ? 100 ASN A HA   1 
ATOM   1557 H  HB2  . ASN A 1 100 ? 36.70600  -19.21200 -44.64200 1.000 37.72000  ? 100 ASN A HB2  1 
ATOM   1558 H  HB3  . ASN A 1 100 ? 35.85800  -18.62000 -43.43600 1.000 37.72000  ? 100 ASN A HB3  1 
ATOM   1559 H  HD21 . ASN A 1 100 ? 34.60400  -16.22200 -45.31500 1.000 44.40000  ? 100 ASN A HD21 1 
ATOM   1560 H  HD22 . ASN A 1 100 ? 34.35200  -17.29000 -44.30700 1.000 44.40000  ? 100 ASN A HD22 1 
ATOM   1561 N  N    . GLY A 1 101 ? 38.46900  -17.15500 -41.18900 1.000 32.76445  ? 101 GLY A N    1 
ATOM   1562 C  CA   . GLY A 1 101 ? 38.33000  -16.28000 -40.05300 1.000 35.34634  ? 101 GLY A CA   1 
ATOM   1563 C  C    . GLY A 1 101 ? 37.54300  -16.84500 -38.89900 1.000 35.93326  ? 101 GLY A C    1 
ATOM   1564 O  O    . GLY A 1 101 ? 37.33200  -16.12200 -37.92200 1.000 32.83025  ? 101 GLY A O    1 
ATOM   1565 H  H    . GLY A 1 101 ? 39.21600  -17.58200 -41.20800 1.000 39.32000  ? 101 GLY A H    1 
ATOM   1566 H  HA2  . GLY A 1 101 ? 39.21500  -16.05700 -39.72400 1.000 42.41000  ? 101 GLY A HA2  1 
ATOM   1567 H  HA3  . GLY A 1 101 ? 37.88600  -15.46800 -40.34100 1.000 42.41000  ? 101 GLY A HA3  1 
ATOM   1568 N  N    . LEU A 1 102 ? 37.11000  -18.10400 -38.97400 1.000 31.29059  ? 102 LEU A N    1 
ATOM   1569 C  CA   . LEU A 1 102 ? 36.29700  -18.73900 -37.94600 1.000 31.35639  ? 102 LEU A CA   1 
ATOM   1570 C  C    . LEU A 1 102 ? 36.99800  -19.96000 -37.37000 1.000 30.50629  ? 102 LEU A C    1 
ATOM   1571 O  O    . LEU A 1 102 ? 37.76300  -20.64500 -38.04900 1.000 30.03255  ? 102 LEU A O    1 
ATOM   1572 C  CB   . LEU A 1 102 ? 34.95200  -19.19300 -38.50400 1.000 29.52459  ? 102 LEU A CB   1 
ATOM   1573 C  CG   . LEU A 1 102 ? 34.07400  -18.11500 -39.13400 1.000 32.32230  ? 102 LEU A CG   1 
ATOM   1574 C  CD1  . LEU A 1 102 ? 32.81000  -18.75900 -39.65400 1.000 37.56503  ? 102 LEU A CD1  1 
ATOM   1575 C  CD2  . LEU A 1 102 ? 33.75900  -17.01200 -38.15800 1.000 38.38618  ? 102 LEU A CD2  1 
ATOM   1576 H  H    . LEU A 1 102 ? 37.28200  -18.62600 -39.63600 1.000 37.55000  ? 102 LEU A H    1 
ATOM   1577 H  HA   . LEU A 1 102 ? 36.15900  -18.09500 -37.23400 1.000 37.63000  ? 102 LEU A HA   1 
ATOM   1578 H  HB2  . LEU A 1 102 ? 35.12000  -19.85900 -39.18900 1.000 35.43000  ? 102 LEU A HB2  1 
ATOM   1579 H  HB3  . LEU A 1 102 ? 34.44300  -19.58600 -37.77800 1.000 35.43000  ? 102 LEU A HB3  1 
ATOM   1580 H  HG   . LEU A 1 102 ? 34.54900  -17.69800 -39.87000 1.000 38.79000  ? 102 LEU A HG   1 
ATOM   1581 H  HD11 . LEU A 1 102 ? 32.25200  -18.07700 -40.06000 1.000 45.08000  ? 102 LEU A HD11 1 
ATOM   1582 H  HD12 . LEU A 1 102 ? 33.04600  -19.43000 -40.31300 1.000 45.08000  ? 102 LEU A HD12 1 
ATOM   1583 H  HD13 . LEU A 1 102 ? 32.33900  -19.17300 -38.91400 1.000 45.08000  ? 102 LEU A HD13 1 
ATOM   1584 H  HD21 . LEU A 1 102 ? 33.11400  -16.41000 -38.56000 1.000 46.06000  ? 102 LEU A HD21 1 
ATOM   1585 H  HD22 . LEU A 1 102 ? 33.39000  -17.40200 -37.35000 1.000 46.06000  ? 102 LEU A HD22 1 
ATOM   1586 H  HD23 . LEU A 1 102 ? 34.57600  -16.53200 -37.95100 1.000 46.06000  ? 102 LEU A HD23 1 
ATOM   1587 N  N    . THR A 1 103 ? 36.72800  -20.24800 -36.10700 1.000 29.49564  ? 103 THR A N    1 
ATOM   1588 C  CA   . THR A 1 103 ? 37.24200  -21.47400 -35.51400 1.000 27.62963  ? 103 THR A CA   1 
ATOM   1589 C  C    . THR A 1 103 ? 36.44000  -22.66700 -36.00700 1.000 26.65583  ? 103 THR A C    1 
ATOM   1590 O  O    . THR A 1 103 ? 35.23300  -22.74900 -35.75400 1.000 29.18245  ? 103 THR A O    1 
ATOM   1591 C  CB   . THR A 1 103 ? 37.18000  -21.38200 -33.99300 1.000 26.27683  ? 103 THR A CB   1 
ATOM   1592 O  OG1  . THR A 1 103 ? 37.81100  -20.15800 -33.61600 1.000 31.04056  ? 103 THR A OG1  1 
ATOM   1593 C  CG2  . THR A 1 103 ? 37.87700  -22.57600 -33.37900 1.000 31.29849  ? 103 THR A CG2  1 
ATOM   1594 H  H    . THR A 1 103 ? 36.25700  -19.75900 -35.58000 1.000 35.40000  ? 103 THR A H    1 
ATOM   1595 H  HA   . THR A 1 103 ? 38.16600  -21.59800 -35.78400 1.000 33.16000  ? 103 THR A HA   1 
ATOM   1596 H  HB   . THR A 1 103 ? 36.26800  -21.39000 -33.66200 1.000 31.53000  ? 103 THR A HB   1 
ATOM   1597 H  HG1  . THR A 1 103 ? 37.77300  -20.06000 -32.78200 1.000 37.25000  ? 103 THR A HG1  1 
ATOM   1598 H  HG21 . THR A 1 103 ? 37.96300  -22.45300 -32.42100 1.000 37.56000  ? 103 THR A HG21 1 
ATOM   1599 H  HG22 . THR A 1 103 ? 37.36600  -23.38200 -33.54900 1.000 37.56000  ? 103 THR A HG22 1 
ATOM   1600 H  HG23 . THR A 1 103 ? 38.76200  -22.67700 -33.76400 1.000 37.56000  ? 103 THR A HG23 1 
ATOM   1601 N  N    . SER A 1 104 ? 37.11100  -23.58700 -36.70200 1.000 27.80070  ? 104 SER A N    1 
ATOM   1602 C  CA   . SER A 1 104 ? 36.52000  -24.84400 -37.11200 1.000 28.09021  ? 104 SER A CA   1 
ATOM   1603 C  C    . SER A 1 104 ? 37.10400  -25.97800 -36.28500 1.000 30.57209  ? 104 SER A C    1 
ATOM   1604 O  O    . SER A 1 104 ? 37.75000  -25.75300 -35.25300 1.000 27.49540  ? 104 SER A O    1 
ATOM   1605 C  CB   . SER A 1 104 ? 36.71400  -25.04300 -38.61500 1.000 25.17933  ? 104 SER A CB   1 
ATOM   1606 O  OG   . SER A 1 104 ? 35.89100  -26.11400 -39.03100 1.000 27.65068  ? 104 SER A OG   1 
ATOM   1607 H  H    . SER A 1 104 ? 37.93000  -23.49500 -36.95100 1.000 33.36000  ? 104 SER A H    1 
ATOM   1608 H  HA   . SER A 1 104 ? 35.56600  -24.81800 -36.94000 1.000 33.71000  ? 104 SER A HA   1 
ATOM   1609 H  HB2  . SER A 1 104 ? 36.45900  -24.23500 -39.08700 1.000 30.22000  ? 104 SER A HB2  1 
ATOM   1610 H  HB3  . SER A 1 104 ? 37.64300  -25.25600 -38.79900 1.000 30.22000  ? 104 SER A HB3  1 
ATOM   1611 H  HG   . SER A 1 104 ? 35.96800  -26.23100 -39.85900 1.000 33.18000  ? 104 SER A HG   1 
ATOM   1612 N  N    . ILE A 1 105 ? 36.82000  -27.20700 -36.70100 1.000 28.42709  ? 105 ILE A N    1 
ATOM   1613 C  CA   . ILE A 1 105 ? 37.37300  -28.38800 -36.04900 1.000 28.98769  ? 105 ILE A CA   1 
ATOM   1614 C  C    . ILE A 1 105 ? 37.84600  -29.34800 -37.12900 1.000 30.37206  ? 105 ILE A C    1 
ATOM   1615 O  O    . ILE A 1 105 ? 37.06600  -29.72400 -38.00700 1.000 29.87200  ? 105 ILE A O    1 
ATOM   1616 C  CB   . ILE A 1 105 ? 36.35200  -29.13800 -35.17800 1.000 30.18520  ? 105 ILE A CB   1 
ATOM   1617 C  CG1  . ILE A 1 105 ? 35.51000  -28.21500 -34.30400 1.000 26.73742  ? 105 ILE A CG1  1 
ATOM   1618 C  CG2  . ILE A 1 105 ? 37.08300  -30.12100 -34.26100 1.000 29.20087  ? 105 ILE A CG2  1 
ATOM   1619 C  CD1  . ILE A 1 105 ? 34.34600  -28.96900 -33.65100 1.000 28.32182  ? 105 ILE A CD1  1 
ATOM   1620 H  H    . ILE A 1 105 ? 36.30400  -27.38500 -37.36600 1.000 34.11000  ? 105 ILE A H    1 
ATOM   1621 H  HA   . ILE A 1 105 ? 38.11100  -28.09300 -35.49300 1.000 34.78000  ? 105 ILE A HA   1 
ATOM   1622 H  HB   . ILE A 1 105 ? 35.75600  -29.59300 -35.79400 1.000 36.22000  ? 105 ILE A HB   1 
ATOM   1623 H  HG12 . ILE A 1 105 ? 36.06600  -27.84300 -33.60100 1.000 32.08000  ? 105 ILE A HG12 1 
ATOM   1624 H  HG13 . ILE A 1 105 ? 35.14500  -27.50100 -34.84900 1.000 32.08000  ? 105 ILE A HG13 1 
ATOM   1625 H  HG21 . ILE A 1 105 ? 36.43200  -30.69800 -33.83200 1.000 35.04000  ? 105 ILE A HG21 1 
ATOM   1626 H  HG22 . ILE A 1 105 ? 37.69600  -30.65300 -34.79300 1.000 35.04000  ? 105 ILE A HG22 1 
ATOM   1627 H  HG23 . ILE A 1 105 ? 37.57500  -29.62200 -33.59100 1.000 35.04000  ? 105 ILE A HG23 1 
ATOM   1628 H  HD11 . ILE A 1 105 ? 33.72300  -28.32600 -33.27800 1.000 33.99000  ? 105 ILE A HD11 1 
ATOM   1629 H  HD12 . ILE A 1 105 ? 33.90200  -29.50800 -34.32500 1.000 33.99000  ? 105 ILE A HD12 1 
ATOM   1630 H  HD13 . ILE A 1 105 ? 34.69400  -29.53900 -32.94800 1.000 33.99000  ? 105 ILE A HD13 1 
ATOM   1631 N  N    . LYS A 1 106 ? 39.10100  -29.76500 -37.05200 1.000 29.88253  ? 106 LYS A N    1 
ATOM   1632 C  CA   . LYS A 1 106 ? 39.56800  -30.84300 -37.90000 1.000 31.61958  ? 106 LYS A CA   1 
ATOM   1633 C  C    . LYS A 1 106 ? 38.76800  -32.10500 -37.62900 1.000 31.63011  ? 106 LYS A C    1 
ATOM   1634 O  O    . LYS A 1 106 ? 38.48400  -32.44700 -36.48300 1.000 30.37206  ? 106 LYS A O    1 
ATOM   1635 C  CB   . LYS A 1 106 ? 41.05200  -31.09200 -37.66500 1.000 30.90371  ? 106 LYS A CB   1 
ATOM   1636 C  CG   . LYS A 1 106 ? 41.62400  -32.21000 -38.51400 1.000 37.27815  ? 106 LYS A CG   1 
ATOM   1637 C  CD   . LYS A 1 106 ? 43.06400  -32.50300 -38.11300 1.000 44.41585  ? 106 LYS A CD   1 
ATOM   1638 C  CE   . LYS A 1 106 ? 43.63100  -33.66000 -38.93200 1.000 60.70991  ? 106 LYS A CE   1 
ATOM   1639 N  NZ   . LYS A 1 106 ? 44.37200  -34.61000 -38.05800 1.000 71.39540  ? 106 LYS A NZ   1 
ATOM   1640 H  H    . LYS A 1 106 ? 39.69600  -29.44100 -36.52100 1.000 35.86000  ? 106 LYS A H    1 
ATOM   1641 H  HA   . LYS A 1 106 ? 39.45100  -30.60100 -38.83200 1.000 37.94000  ? 106 LYS A HA   1 
ATOM   1642 H  HB2  . LYS A 1 106 ? 41.54200  -30.28100 -37.87300 1.000 37.09000  ? 106 LYS A HB2  1 
ATOM   1643 H  HB3  . LYS A 1 106 ? 41.18500  -31.33000 -36.73400 1.000 37.09000  ? 106 LYS A HB3  1 
ATOM   1644 H  HG2  . LYS A 1 106 ? 41.09900  -33.01500 -38.38800 1.000 44.73000  ? 106 LYS A HG2  1 
ATOM   1645 H  HG3  . LYS A 1 106 ? 41.61100  -31.94700 -39.44800 1.000 44.73000  ? 106 LYS A HG3  1 
ATOM   1646 H  HD2  . LYS A 1 106 ? 43.61000  -31.71700 -38.27100 1.000 53.30000  ? 106 LYS A HD2  1 
ATOM   1647 H  HD3  . LYS A 1 106 ? 43.09600  -32.74600 -37.17500 1.000 53.30000  ? 106 LYS A HD3  1 
ATOM   1648 H  HE2  . LYS A 1 106 ? 42.90600  -34.13900 -39.36300 1.000 72.85000  ? 106 LYS A HE2  1 
ATOM   1649 H  HE3  . LYS A 1 106 ? 44.24400  -33.31400 -39.60100 1.000 72.85000  ? 106 LYS A HE3  1 
ATOM   1650 H  HZ1  . LYS A 1 106 ? 44.68600  -35.28800 -38.54200 1.000 85.67000  ? 106 LYS A HZ1  1 
ATOM   1651 H  HZ2  . LYS A 1 106 ? 45.05500  -34.19400 -37.66700 1.000 85.67000  ? 106 LYS A HZ2  1 
ATOM   1652 H  HZ3  . LYS A 1 106 ? 43.83000  -34.93100 -37.42900 1.000 85.67000  ? 106 LYS A HZ3  1 
ATOM   1653 N  N    . TRP A 1 107 ? 38.40000  -32.81000 -38.69400 1.000 30.29311  ? 107 TRP A N    1 
ATOM   1654 C  CA   . TRP A 1 107 ? 37.54200  -33.97300 -38.52100 1.000 29.76409  ? 107 TRP A CA   1 
ATOM   1655 C  C    . TRP A 1 107 ? 38.23900  -35.03900 -37.69000 1.000 31.28007  ? 107 TRP A C    1 
ATOM   1656 O  O    . TRP A 1 107 ? 39.40700  -35.37900 -37.93000 1.000 30.94318  ? 107 TRP A O    1 
ATOM   1657 C  CB   . TRP A 1 107 ? 37.12700  -34.58600 -39.86500 1.000 29.20087  ? 107 TRP A CB   1 
ATOM   1658 C  CG   . TRP A 1 107 ? 36.12300  -35.70400 -39.63600 1.000 28.93768  ? 107 TRP A CG   1 
ATOM   1659 C  CD1  . TRP A 1 107 ? 34.76100  -35.57000 -39.56800 1.000 31.24322  ? 107 TRP A CD1  1 
ATOM   1660 C  CD2  . TRP A 1 107 ? 36.39700  -37.08700 -39.37000 1.000 29.55618  ? 107 TRP A CD2  1 
ATOM   1661 N  NE1  . TRP A 1 107 ? 34.18000  -36.77500 -39.30400 1.000 30.37733  ? 107 TRP A NE1  1 
ATOM   1662 C  CE2  . TRP A 1 107 ? 35.15700  -37.72600 -39.17700 1.000 31.85119  ? 107 TRP A CE2  1 
ATOM   1663 C  CE3  . TRP A 1 107 ? 37.56600  -37.84700 -39.27000 1.000 33.28557  ? 107 TRP A CE3  1 
ATOM   1664 C  CZ2  . TRP A 1 107 ? 35.05100  -39.08800 -38.91300 1.000 33.18029  ? 107 TRP A CZ2  1 
ATOM   1665 C  CZ3  . TRP A 1 107 ? 37.45600  -39.20300 -39.00900 1.000 33.49875  ? 107 TRP A CZ3  1 
ATOM   1666 C  CH2  . TRP A 1 107 ? 36.21100  -39.80700 -38.82700 1.000 33.47243  ? 107 TRP A CH2  1 
ATOM   1667 H  H    . TRP A 1 107 ? 38.62800  -32.63900 -39.50500 1.000 36.35000  ? 107 TRP A H    1 
ATOM   1668 H  HA   . TRP A 1 107 ? 36.73900  -33.67400 -38.06600 1.000 35.72000  ? 107 TRP A HA   1 
ATOM   1669 H  HB2  . TRP A 1 107 ? 36.71600  -33.90600 -40.42100 1.000 35.04000  ? 107 TRP A HB2  1 
ATOM   1670 H  HB3  . TRP A 1 107 ? 37.90700  -34.95200 -40.31100 1.000 35.04000  ? 107 TRP A HB3  1 
ATOM   1671 H  HD1  . TRP A 1 107 ? 34.29800  -34.77200 -39.68500 1.000 37.49000  ? 107 TRP A HD1  1 
ATOM   1672 H  HE1  . TRP A 1 107 ? 33.33500  -36.91600 -39.22800 1.000 36.45000  ? 107 TRP A HE1  1 
ATOM   1673 H  HE3  . TRP A 1 107 ? 38.40000  -37.45100 -39.37700 1.000 39.94000  ? 107 TRP A HE3  1 
ATOM   1674 H  HZ2  . TRP A 1 107 ? 34.22200  -39.49500 -38.79900 1.000 39.82000  ? 107 TRP A HZ2  1 
ATOM   1675 H  HZ3  . TRP A 1 107 ? 38.22600  -39.72100 -38.95400 1.000 40.20000  ? 107 TRP A HZ3  1 
ATOM   1676 H  HH2  . TRP A 1 107 ? 36.17000  -40.71700 -38.64300 1.000 40.17000  ? 107 TRP A HH2  1 
ATOM   1677 N  N    . ALA A 1 108 ? 37.50000  -35.57200 -36.71800 1.000 29.98517  ? 108 ALA A N    1 
ATOM   1678 C  CA   . ALA A 1 108 ? 37.91000  -36.66600 -35.85400 1.000 30.41154  ? 108 ALA A CA   1 
ATOM   1679 C  C    . ALA A 1 108 ? 36.64700  -37.16000 -35.16900 1.000 27.93756  ? 108 ALA A C    1 
ATOM   1680 O  O    . ALA A 1 108 ? 35.71700  -36.38700 -34.94800 1.000 27.09272  ? 108 ALA A O    1 
ATOM   1681 C  CB   . ALA A 1 108 ? 38.94100  -36.22500 -34.80600 1.000 32.99869  ? 108 ALA A CB   1 
ATOM   1682 H  H    . ALA A 1 108 ? 36.70800  -35.29600 -36.53000 1.000 35.99000  ? 108 ALA A H    1 
ATOM   1683 H  HA   . ALA A 1 108 ? 38.31700  -37.37700 -36.37400 1.000 36.49000  ? 108 ALA A HA   1 
ATOM   1684 H  HB1  . ALA A 1 108 ? 39.17800  -36.98800 -34.25600 1.000 39.60000  ? 108 ALA A HB1  1 
ATOM   1685 H  HB2  . ALA A 1 108 ? 39.72800  -35.88700 -35.26000 1.000 39.60000  ? 108 ALA A HB2  1 
ATOM   1686 H  HB3  . ALA A 1 108 ? 38.55200  -35.52800 -34.25400 1.000 39.60000  ? 108 ALA A HB3  1 
ATOM   1687 N  N    . ASP A 1 109 ? 36.61100  -38.45000 -34.86600 1.000 31.90909  ? 109 ASP A N    1 
ATOM   1688 C  CA   . ASP A 1 109 ? 35.58300  -38.98600 -33.97600 1.000 28.29023  ? 109 ASP A CA   1 
ATOM   1689 C  C    . ASP A 1 109 ? 34.17900  -38.55800 -34.41200 1.000 29.36405  ? 109 ASP A C    1 
ATOM   1690 O  O    . ASP A 1 109 ? 33.32900  -38.20200 -33.59600 1.000 29.85621  ? 109 ASP A O    1 
ATOM   1691 C  CB   . ASP A 1 109 ? 35.85500  -38.54300 -32.53400 1.000 28.12442  ? 109 ASP A CB   1 
ATOM   1692 C  CG   . ASP A 1 109 ? 37.18700  -39.03300 -31.99400 1.000 32.69339  ? 109 ASP A CG   1 
ATOM   1693 O  OD1  . ASP A 1 109 ? 37.41400  -40.25600 -31.93200 1.000 32.84078  ? 109 ASP A OD1  1 
ATOM   1694 O  OD2  . ASP A 1 109 ? 37.99800  -38.18800 -31.57900 1.000 34.12514  ? 109 ASP A OD2  1 
ATOM   1695 H  H    . ASP A 1 109 ? 37.16800  -39.03600 -35.16000 1.000 38.29000  ? 109 ASP A H    1 
ATOM   1696 H  HA   . ASP A 1 109 ? 35.61300  -39.95400 -34.02200 1.000 33.95000  ? 109 ASP A HA   1 
ATOM   1697 H  HB2  . ASP A 1 109 ? 35.85900  -37.57300 -32.49900 1.000 33.75000  ? 109 ASP A HB2  1 
ATOM   1698 H  HB3  . ASP A 1 109 ? 35.15500  -38.89300 -31.96100 1.000 33.75000  ? 109 ASP A HB3  1 
ATOM   1699 N  N    . ASN A 1 110 ? 33.91300  -38.61200 -35.72200 1.000 28.82188  ? 110 ASN A N    1 
ATOM   1700 C  CA   . ASN A 1 110 ? 32.56300  -38.35700 -36.22600 1.000 30.66683  ? 110 ASN A CA   1 
ATOM   1701 C  C    . ASN A 1 110 ? 32.03000  -37.00100 -35.78100 1.000 28.47710  ? 110 ASN A C    1 
ATOM   1702 O  O    . ASN A 1 110 ? 30.83800  -36.85600 -35.47500 1.000 31.81434  ? 110 ASN A O    1 
ATOM   1703 C  CB   . ASN A 1 110 ? 31.59500  -39.46000 -35.78800 1.000 30.25889  ? 110 ASN A CB   1 
ATOM   1704 C  CG   . ASN A 1 110 ? 32.02900  -40.82600 -36.23500 1.000 33.23293  ? 110 ASN A CG   1 
ATOM   1705 O  OD1  . ASN A 1 110 ? 32.45000  -41.02000 -37.37400 1.000 33.53823  ? 110 ASN A OD1  1 
ATOM   1706 N  ND2  . ASN A 1 110 ? 31.96700  -41.78900 -35.32500 1.000 33.85669  ? 110 ASN A ND2  1 
ATOM   1707 H  H    . ASN A 1 110 ? 34.49400  -38.79200 -36.33000 1.000 34.59000  ? 110 ASN A H    1 
ATOM   1708 H  HA   . ASN A 1 110 ? 32.61500  -38.34600 -37.19400 1.000 36.80000  ? 110 ASN A HA   1 
ATOM   1709 H  HB2  . ASN A 1 110 ? 31.53900  -39.46500 -34.82000 1.000 36.31000  ? 110 ASN A HB2  1 
ATOM   1710 H  HB3  . ASN A 1 110 ? 30.72100  -39.28300 -36.17000 1.000 36.31000  ? 110 ASN A HB3  1 
ATOM   1711 H  HD21 . ASN A 1 110 ? 32.20400  -42.59000 -35.52900 1.000 40.63000  ? 110 ASN A HD21 1 
ATOM   1712 H  HD22 . ASN A 1 110 ? 31.68900  -41.61200 -34.53000 1.000 40.63000  ? 110 ASN A HD22 1 
ATOM   1713 N  N    . ASN A 1 111 ? 32.89700  -35.98500 -35.76100 1.000 27.54014  ? 111 ASN A N    1 
ATOM   1714 C  CA   . ASN A 1 111 ? 32.55400  -34.69600 -35.17100 1.000 27.42171  ? 111 ASN A CA   1 
ATOM   1715 C  C    . ASN A 1 111 ? 32.09200  -33.63900 -36.18600 1.000 27.33749  ? 111 ASN A C    1 
ATOM   1716 O  O    . ASN A 1 111 ? 32.07600  -32.44600 -35.85100 1.000 27.44013  ? 111 ASN A O    1 
ATOM   1717 C  CB   . ASN A 1 111 ? 33.74200  -34.16200 -34.36100 1.000 27.42960  ? 111 ASN A CB   1 
ATOM   1718 C  CG   . ASN A 1 111 ? 34.91000  -33.69300 -35.23100 1.000 29.37984  ? 111 ASN A CG   1 
ATOM   1719 O  OD1  . ASN A 1 111 ? 34.88000  -33.76300 -36.45100 1.000 27.85860  ? 111 ASN A OD1  1 
ATOM   1720 N  ND2  . ASN A 1 111 ? 35.97700  -33.25100 -34.57800 1.000 26.44001  ? 111 ASN A ND2  1 
ATOM   1721 H  H    . ASN A 1 111 ? 33.69200  -36.02200 -36.08600 1.000 33.05000  ? 111 ASN A H    1 
ATOM   1722 H  HA   . ASN A 1 111 ? 31.80500  -34.84500 -34.57200 1.000 32.91000  ? 111 ASN A HA   1 
ATOM   1723 H  HB2  . ASN A 1 111 ? 33.44500  -33.40600 -33.83000 1.000 32.92000  ? 111 ASN A HB2  1 
ATOM   1724 H  HB3  . ASN A 1 111 ? 34.06800  -34.86700 -33.78100 1.000 32.92000  ? 111 ASN A HB3  1 
ATOM   1725 H  HD21 . ASN A 1 111 ? 36.66400  -32.97500 -35.01500 1.000 31.73000  ? 111 ASN A HD21 1 
ATOM   1726 H  HD22 . ASN A 1 111 ? 35.98200  -33.24200 -33.71800 1.000 31.73000  ? 111 ASN A HD22 1 
ATOM   1727 N  N    . SER A 1 112 ? 31.65600  -34.03300 -37.38600 1.000 27.82702  ? 112 SER A N    1 
ATOM   1728 C  CA   . SER A 1 112 ? 31.27000  -33.00200 -38.35000 1.000 28.21654  ? 112 SER A CA   1 
ATOM   1729 C  C    . SER A 1 112 ? 30.06600  -32.19400 -37.87500 1.000 25.81889  ? 112 SER A C    1 
ATOM   1730 O  O    . SER A 1 112 ? 29.97600  -30.99100 -38.14800 1.000 24.32923  ? 112 SER A O    1 
ATOM   1731 C  CB   . SER A 1 112 ? 31.01200  -33.62200 -39.73400 1.000 26.12682  ? 112 SER A CB   1 
ATOM   1732 O  OG   . SER A 1 112 ? 29.79800  -34.34600 -39.82300 1.000 27.81649  ? 112 SER A OG   1 
ATOM   1733 H  H    . SER A 1 112 ? 31.57800  -34.84700 -37.65200 1.000 33.39000  ? 112 SER A H    1 
ATOM   1734 H  HA   . SER A 1 112 ? 32.01100  -32.38300 -38.44700 1.000 33.86000  ? 112 SER A HA   1 
ATOM   1735 H  HB2  . SER A 1 112 ? 30.98600  -32.90600 -40.38700 1.000 31.35000  ? 112 SER A HB2  1 
ATOM   1736 H  HB3  . SER A 1 112 ? 31.74200  -34.22900 -39.93500 1.000 31.35000  ? 112 SER A HB3  1 
ATOM   1737 H  HG   . SER A 1 112 ? 29.81300  -34.99800 -39.29300 1.000 33.38000  ? 112 SER A HG   1 
ATOM   1738 N  N    . TYR A 1 113 ? 29.15700  -32.80900 -37.11000 1.000 25.72940  ? 113 TYR A N    1 
ATOM   1739 C  CA   . TYR A 1 113 ? 28.01100  -32.06300 -36.59400 1.000 26.56371  ? 113 TYR A CA   1 
ATOM   1740 C  C    . TYR A 1 113 ? 28.46200  -30.97700 -35.62200 1.000 26.90059  ? 113 TYR A C    1 
ATOM   1741 O  O    . TYR A 1 113 ? 27.87200  -29.89000 -35.58800 1.000 25.83204  ? 113 TYR A O    1 
ATOM   1742 C  CB   . TYR A 1 113 ? 27.00300  -33.03700 -35.94100 1.000 26.94007  ? 113 TYR A CB   1 
ATOM   1743 C  CG   . TYR A 1 113 ? 27.28500  -33.49200 -34.52500 1.000 24.88719  ? 113 TYR A CG   1 
ATOM   1744 C  CD1  . TYR A 1 113 ? 28.13600  -34.55700 -34.26900 1.000 27.04272  ? 113 TYR A CD1  1 
ATOM   1745 C  CD2  . TYR A 1 113 ? 26.63100  -32.89700 -33.46100 1.000 26.37421  ? 113 TYR A CD2  1 
ATOM   1746 C  CE1  . TYR A 1 113 ? 28.37100  -34.97500 -32.95400 1.000 27.68753  ? 113 TYR A CE1  1 
ATOM   1747 C  CE2  . TYR A 1 113 ? 26.86300  -33.31200 -32.14500 1.000 24.40029  ? 113 TYR A CE2  1 
ATOM   1748 C  CZ   . TYR A 1 113 ? 27.73000  -34.35200 -31.91900 1.000 26.88743  ? 113 TYR A CZ   1 
ATOM   1749 O  OH   . TYR A 1 113 ? 27.96500  -34.79100 -30.63200 1.000 25.32935  ? 113 TYR A OH   1 
ATOM   1750 H  H    . TYR A 1 113 ? 29.18100  -33.63800 -36.88300 1.000 30.88000  ? 113 TYR A H    1 
ATOM   1751 H  HA   . TYR A 1 113 ? 27.54700  -31.62200 -37.32300 1.000 31.87000  ? 113 TYR A HA   1 
ATOM   1752 H  HB2  . TYR A 1 113 ? 26.13600  -32.60300 -35.92900 1.000 32.33000  ? 113 TYR A HB2  1 
ATOM   1753 H  HB3  . TYR A 1 113 ? 26.96500  -33.83700 -36.48900 1.000 32.33000  ? 113 TYR A HB3  1 
ATOM   1754 H  HD1  . TYR A 1 113 ? 28.55300  -34.99600 -34.97500 1.000 32.45000  ? 113 TYR A HD1  1 
ATOM   1755 H  HD2  . TYR A 1 113 ? 26.02700  -32.21000 -33.62300 1.000 31.65000  ? 113 TYR A HD2  1 
ATOM   1756 H  HE1  . TYR A 1 113 ? 28.96100  -35.67300 -32.78500 1.000 33.22000  ? 113 TYR A HE1  1 
ATOM   1757 H  HE2  . TYR A 1 113 ? 26.43600  -32.89000 -31.43400 1.000 29.28000  ? 113 TYR A HE2  1 
ATOM   1758 H  HH   . TYR A 1 113 ? 27.50000  -34.35000 -30.08900 1.000 30.39000  ? 113 TYR A HH   1 
ATOM   1759 N  N    . LEU A 1 114 ? 29.53300  -31.22500 -34.86000 1.000 25.95048  ? 114 LEU A N    1 
ATOM   1760 C  CA   . LEU A 1 114 ? 30.02400  -30.20100 -33.94500 1.000 25.80309  ? 114 LEU A CA   1 
ATOM   1761 C  C    . LEU A 1 114 ? 30.73100  -29.09000 -34.68500 1.000 26.21367  ? 114 LEU A C    1 
ATOM   1762 O  O    . LEU A 1 114 ? 30.61400  -27.91400 -34.31400 1.000 26.12418  ? 114 LEU A O    1 
ATOM   1763 C  CB   . LEU A 1 114 ? 30.95700  -30.80900 -32.90400 1.000 26.30842  ? 114 LEU A CB   1 
ATOM   1764 C  CG   . LEU A 1 114 ? 30.25100  -31.78900 -31.98600 1.000 31.94330  ? 114 LEU A CG   1 
ATOM   1765 C  CD1  . LEU A 1 114 ? 31.28000  -32.63600 -31.26400 1.000 35.73586  ? 114 LEU A CD1  1 
ATOM   1766 C  CD2  . LEU A 1 114 ? 29.39500  -31.02800 -30.96600 1.000 28.85609  ? 114 LEU A CD2  1 
ATOM   1767 H  H    . LEU A 1 114 ? 29.97900  -31.96000 -34.85700 1.000 31.14000  ? 114 LEU A H    1 
ATOM   1768 H  HA   . LEU A 1 114 ? 29.26000  -29.82500 -33.48000 1.000 30.97000  ? 114 LEU A HA   1 
ATOM   1769 H  HB2  . LEU A 1 114 ? 31.67100  -31.28300 -33.35900 1.000 31.57000  ? 114 LEU A HB2  1 
ATOM   1770 H  HB3  . LEU A 1 114 ? 31.32600  -30.09700 -32.35800 1.000 31.57000  ? 114 LEU A HB3  1 
ATOM   1771 H  HG   . LEU A 1 114 ? 29.67200  -32.36800 -32.50700 1.000 38.33000  ? 114 LEU A HG   1 
ATOM   1772 H  HD11 . LEU A 1 114 ? 30.82100  -33.25600 -30.67600 1.000 42.88000  ? 114 LEU A HD11 1 
ATOM   1773 H  HD12 . LEU A 1 114 ? 31.80100  -33.12600 -31.91900 1.000 42.88000  ? 114 LEU A HD12 1 
ATOM   1774 H  HD13 . LEU A 1 114 ? 31.85900  -32.05500 -30.74700 1.000 42.88000  ? 114 LEU A HD13 1 
ATOM   1775 H  HD21 . LEU A 1 114 ? 28.95800  -31.66700 -30.38200 1.000 34.63000  ? 114 LEU A HD21 1 
ATOM   1776 H  HD22 . LEU A 1 114 ? 29.96900  -30.44400 -30.44600 1.000 34.63000  ? 114 LEU A HD22 1 
ATOM   1777 H  HD23 . LEU A 1 114 ? 28.73100  -30.50400 -31.44000 1.000 34.63000  ? 114 LEU A HD23 1 
ATOM   1778 N  N    . ALA A 1 115 ? 31.46100  -29.43900 -35.74600 1.000 27.50067  ? 115 ALA A N    1 
ATOM   1779 C  CA   . ALA A 1 115 ? 32.14200  -28.42500 -36.53300 1.000 29.54302  ? 115 ALA A CA   1 
ATOM   1780 C  C    . ALA A 1 115 ? 31.13800  -27.43300 -37.08900 1.000 23.43702  ? 115 ALA A C    1 
ATOM   1781 O  O    . ALA A 1 115 ? 31.31700  -26.21600 -36.98100 1.000 26.71899  ? 115 ALA A O    1 
ATOM   1782 C  CB   . ALA A 1 115 ? 32.93900  -29.09200 -37.64900 1.000 27.61121  ? 115 ALA A CB   1 
ATOM   1783 H  H    . ALA A 1 115 ? 31.57400  -30.24600 -36.02300 1.000 33.00000  ? 115 ALA A H    1 
ATOM   1784 H  HA   . ALA A 1 115 ? 32.77000  -27.93900 -35.97600 1.000 35.45000  ? 115 ALA A HA   1 
ATOM   1785 H  HB1  . ALA A 1 115 ? 33.39400  -28.40900 -38.16500 1.000 33.13000  ? 115 ALA A HB1  1 
ATOM   1786 H  HB2  . ALA A 1 115 ? 33.58700  -29.69700 -37.25600 1.000 33.13000  ? 115 ALA A HB2  1 
ATOM   1787 H  HB3  . ALA A 1 115 ? 32.33000  -29.58600 -38.22000 1.000 33.13000  ? 115 ALA A HB3  1 
ATOM   1788 N  N    . THR A 1 116 ? 30.06500  -27.93400 -37.69600 1.000 28.21391  ? 116 THR A N    1 
ATOM   1789 C  CA   . THR A 1 116 ? 29.13700  -27.00900 -38.31700 1.000 27.27959  ? 116 THR A CA   1 
ATOM   1790 C  C    . THR A 1 116 ? 28.34800  -26.23400 -37.27000 1.000 26.18472  ? 116 THR A C    1 
ATOM   1791 O  O    . THR A 1 116 ? 28.05700  -25.05200 -37.47900 1.000 26.66636  ? 116 THR A O    1 
ATOM   1792 C  CB   . THR A 1 116 ? 28.21600  -27.74200 -39.30200 1.000 30.75369  ? 116 THR A CB   1 
ATOM   1793 O  OG1  . THR A 1 116 ? 27.43200  -26.74700 -39.98100 1.000 30.68789  ? 116 THR A OG1  1 
ATOM   1794 C  CG2  . THR A 1 116 ? 27.30700  -28.71700 -38.63700 1.000 32.70655  ? 116 THR A CG2  1 
ATOM   1795 H  H    . THR A 1 116 ? 29.86500  -28.76800 -37.75800 1.000 33.85000  ? 116 THR A H    1 
ATOM   1796 H  HA   . THR A 1 116 ? 29.63400  -26.36200 -38.84200 1.000 32.73000  ? 116 THR A HA   1 
ATOM   1797 H  HB   . THR A 1 116 ? 28.75500  -28.26000 -39.92000 1.000 36.90000  ? 116 THR A HB   1 
ATOM   1798 H  HG1  . THR A 1 116 ? 26.85900  -27.11700 -40.47100 1.000 36.82000  ? 116 THR A HG1  1 
ATOM   1799 H  HG21 . THR A 1 116 ? 26.81000  -29.21700 -39.30400 1.000 39.25000  ? 116 THR A HG21 1 
ATOM   1800 H  HG22 . THR A 1 116 ? 27.82200  -29.33800 -38.09800 1.000 39.25000  ? 116 THR A HG22 1 
ATOM   1801 H  HG23 . THR A 1 116 ? 26.68000  -28.24900 -38.06300 1.000 39.25000  ? 116 THR A HG23 1 
ATOM   1802 N  N    . ALA A 1 117 ? 28.05800  -26.84100 -36.11300 1.000 25.87942  ? 117 ALA A N    1 
ATOM   1803 C  CA   . ALA A 1 117 ? 27.42300  -26.08400 -35.03700 1.000 27.75596  ? 117 ALA A CA   1 
ATOM   1804 C  C    . ALA A 1 117 ? 28.32800  -24.95600 -34.54900 1.000 26.01891  ? 117 ALA A C    1 
ATOM   1805 O  O    . ALA A 1 117 ? 27.88200  -23.81700 -34.36400 1.000 26.02944  ? 117 ALA A O    1 
ATOM   1806 C  CB   . ALA A 1 117 ? 27.05700  -27.02300 -33.88700 1.000 26.59529  ? 117 ALA A CB   1 
ATOM   1807 H  H    . ALA A 1 117 ? 28.21600  -27.66700 -35.93400 1.000 31.05000  ? 117 ALA A H    1 
ATOM   1808 H  HA   . ALA A 1 117 ? 26.60500  -25.68700 -35.37300 1.000 33.31000  ? 117 ALA A HA   1 
ATOM   1809 H  HB1  . ALA A 1 117 ? 26.64300  -26.50700 -33.17700 1.000 31.91000  ? 117 ALA A HB1  1 
ATOM   1810 H  HB2  . ALA A 1 117 ? 26.43700  -27.69500 -34.21200 1.000 31.91000  ? 117 ALA A HB2  1 
ATOM   1811 H  HB3  . ALA A 1 117 ? 27.86400  -27.44900 -33.55800 1.000 31.91000  ? 117 ALA A HB3  1 
ATOM   1812 N  N    . LEU A 1 118 ? 29.61300  -25.25800 -34.34500 1.000 25.14249  ? 118 LEU A N    1 
ATOM   1813 C  CA   . LEU A 1 118 ? 30.54300  -24.25400 -33.84200 1.000 26.55845  ? 118 LEU A CA   1 
ATOM   1814 C  C    . LEU A 1 118 ? 30.70100  -23.11300 -34.83000 1.000 28.49552  ? 118 LEU A C    1 
ATOM   1815 O  O    . LEU A 1 118 ? 30.71000  -21.93600 -34.45200 1.000 26.56634  ? 118 LEU A O    1 
ATOM   1816 C  CB   . LEU A 1 118 ? 31.88600  -24.92400 -33.52400 1.000 26.53739  ? 118 LEU A CB   1 
ATOM   1817 C  CG   . LEU A 1 118 ? 33.06900  -24.04100 -33.18900 1.000 27.66911  ? 118 LEU A CG   1 
ATOM   1818 C  CD1  . LEU A 1 118 ? 32.68200  -23.24100 -31.93300 1.000 32.16965  ? 118 LEU A CD1  1 
ATOM   1819 C  CD2  . LEU A 1 118 ? 34.34400  -24.83700 -32.91200 1.000 28.98505  ? 118 LEU A CD2  1 
ATOM   1820 H  H    . LEU A 1 118 ? 29.96500  -26.02900 -34.49000 1.000 30.17000  ? 118 LEU A H    1 
ATOM   1821 H  HA   . LEU A 1 118 ? 30.20300  -23.87100 -33.01800 1.000 31.87000  ? 118 LEU A HA   1 
ATOM   1822 H  HB2  . LEU A 1 118 ? 31.75000  -25.50600 -32.76000 1.000 31.84000  ? 118 LEU A HB2  1 
ATOM   1823 H  HB3  . LEU A 1 118 ? 32.14300  -25.44900 -34.29800 1.000 31.84000  ? 118 LEU A HB3  1 
ATOM   1824 H  HG   . LEU A 1 118 ? 33.27000  -23.46500 -33.94400 1.000 33.20000  ? 118 LEU A HG   1 
ATOM   1825 H  HD11 . LEU A 1 118 ? 33.46200  -22.76500 -31.60900 1.000 38.60000  ? 118 LEU A HD11 1 
ATOM   1826 H  HD12 . LEU A 1 118 ? 31.98200  -22.61000 -32.16400 1.000 38.60000  ? 118 LEU A HD12 1 
ATOM   1827 H  HD13 . LEU A 1 118 ? 32.36200  -23.85500 -31.25400 1.000 38.60000  ? 118 LEU A HD13 1 
ATOM   1828 H  HD21 . LEU A 1 118 ? 35.06800  -24.21900 -32.72700 1.000 34.78000  ? 118 LEU A HD21 1 
ATOM   1829 H  HD22 . LEU A 1 118 ? 34.19600  -25.41200 -32.14500 1.000 34.78000  ? 118 LEU A HD22 1 
ATOM   1830 H  HD23 . LEU A 1 118 ? 34.55700  -25.37300 -33.69200 1.000 34.78000  ? 118 LEU A HD23 1 
ATOM   1831 N  N    . LEU A 1 119 ? 30.78200  -23.43600 -36.11300 1.000 25.94258  ? 119 LEU A N    1 
ATOM   1832 C  CA   . LEU A 1 119 ? 30.90500  -22.39500 -37.11900 1.000 25.74519  ? 119 LEU A CA   1 
ATOM   1833 C  C    . LEU A 1 119 ? 29.65300  -21.53000 -37.15500 1.000 26.57687  ? 119 LEU A C    1 
ATOM   1834 O  O    . LEU A 1 119 ? 29.73400  -20.30600 -37.31100 1.000 30.21941  ? 119 LEU A O    1 
ATOM   1835 C  CB   . LEU A 1 119 ? 31.15500  -23.05300 -38.48300 1.000 27.80597  ? 119 LEU A CB   1 
ATOM   1836 C  CG   . LEU A 1 119 ? 32.51400  -23.72900 -38.62200 1.000 29.10349  ? 119 LEU A CG   1 
ATOM   1837 C  CD1  . LEU A 1 119 ? 32.48900  -24.67200 -39.81300 1.000 29.35352  ? 119 LEU A CD1  1 
ATOM   1838 C  CD2  . LEU A 1 119 ? 33.59300  -22.69800 -38.81600 1.000 29.48511  ? 119 LEU A CD2  1 
ATOM   1839 H  H    . LEU A 1 119 ? 30.76800  -24.23800 -36.42300 1.000 31.13000  ? 119 LEU A H    1 
ATOM   1840 H  HA   . LEU A 1 119 ? 31.65700  -21.81800 -36.91300 1.000 30.89000  ? 119 LEU A HA   1 
ATOM   1841 H  HB2  . LEU A 1 119 ? 30.47500  -23.73000 -38.62700 1.000 33.37000  ? 119 LEU A HB2  1 
ATOM   1842 H  HB3  . LEU A 1 119 ? 31.09400  -22.37100 -39.17000 1.000 33.37000  ? 119 LEU A HB3  1 
ATOM   1843 H  HG   . LEU A 1 119 ? 32.71200  -24.23200 -37.81700 1.000 34.92000  ? 119 LEU A HG   1 
ATOM   1844 H  HD11 . LEU A 1 119 ? 33.36200  -25.08200 -39.91000 1.000 35.23000  ? 119 LEU A HD11 1 
ATOM   1845 H  HD12 . LEU A 1 119 ? 31.81700  -25.35500 -39.66000 1.000 35.23000  ? 119 LEU A HD12 1 
ATOM   1846 H  HD13 . LEU A 1 119 ? 32.27000  -24.16700 -40.61200 1.000 35.23000  ? 119 LEU A HD13 1 
ATOM   1847 H  HD21 . LEU A 1 119 ? 34.44600  -23.14800 -38.92100 1.000 35.38000  ? 119 LEU A HD21 1 
ATOM   1848 H  HD22 . LEU A 1 119 ? 33.39400  -22.17700 -39.60900 1.000 35.38000  ? 119 LEU A HD22 1 
ATOM   1849 H  HD23 . LEU A 1 119 ? 33.61900  -22.11800 -38.03800 1.000 35.38000  ? 119 LEU A HD23 1 
ATOM   1850 N  N    . THR A 1 120 ? 28.48600  -22.15400 -36.98500 1.000 27.45066  ? 120 THR A N    1 
ATOM   1851 C  CA   . THR A 1 120 ? 27.23400  -21.41400 -36.98900 1.000 29.34299  ? 120 THR A CA   1 
ATOM   1852 C  C    . THR A 1 120 ? 27.18400  -20.42300 -35.84200 1.000 27.35328  ? 120 THR A C    1 
ATOM   1853 O  O    . THR A 1 120 ? 26.78200  -19.26800 -36.02800 1.000 27.20063  ? 120 THR A O    1 
ATOM   1854 C  CB   . THR A 1 120 ? 26.05700  -22.38700 -36.91800 1.000 27.27959  ? 120 THR A CB   1 
ATOM   1855 O  OG1  . THR A 1 120 ? 26.05900  -23.24700 -38.07500 1.000 28.44552  ? 120 THR A OG1  1 
ATOM   1856 C  CG2  . THR A 1 120 ? 24.74400  -21.62100 -36.84300 1.000 28.66923  ? 120 THR A CG2  1 
ATOM   1857 H  H    . THR A 1 120 ? 28.39500  -23.00100 -36.86700 1.000 32.94000  ? 120 THR A H    1 
ATOM   1858 H  HA   . THR A 1 120 ? 27.16200  -20.91600 -37.81800 1.000 35.21000  ? 120 THR A HA   1 
ATOM   1859 H  HB   . THR A 1 120 ? 26.13600  -22.93600 -36.12200 1.000 32.74000  ? 120 THR A HB   1 
ATOM   1860 H  HG1  . THR A 1 120 ? 26.78100  -23.67500 -38.11300 1.000 34.13000  ? 120 THR A HG1  1 
ATOM   1861 H  HG21 . THR A 1 120 ? 23.99800  -22.23000 -36.95800 1.000 34.40000  ? 120 THR A HG21 1 
ATOM   1862 H  HG22 . THR A 1 120 ? 24.66400  -21.18400 -35.98100 1.000 34.40000  ? 120 THR A HG22 1 
ATOM   1863 H  HG23 . THR A 1 120 ? 24.71200  -20.94900 -37.54100 1.000 34.40000  ? 120 THR A HG23 1 
ATOM   1864 N  N    . LEU A 1 121 ? 27.58600  -20.85400 -34.64400 1.000 26.78479  ? 121 LEU A N    1 
ATOM   1865 C  CA   . LEU A 1 121 ? 27.48500  -19.97200 -33.48700 1.000 28.80609  ? 121 LEU A CA   1 
ATOM   1866 C  C    . LEU A 1 121 ? 28.26200  -18.68800 -33.70800 1.000 30.86159  ? 121 LEU A C    1 
ATOM   1867 O  O    . LEU A 1 121 ? 27.84300  -17.62300 -33.25500 1.000 29.19034  ? 121 LEU A O    1 
ATOM   1868 C  CB   . LEU A 1 121 ? 27.99900  -20.67000 -32.23000 1.000 25.89521  ? 121 LEU A CB   1 
ATOM   1869 C  CG   . LEU A 1 121 ? 27.16000  -21.81300 -31.65500 1.000 29.35089  ? 121 LEU A CG   1 
ATOM   1870 C  CD1  . LEU A 1 121 ? 27.91600  -22.54000 -30.57200 1.000 31.86435  ? 121 LEU A CD1  1 
ATOM   1871 C  CD2  . LEU A 1 121 ? 25.86200  -21.23200 -31.09600 1.000 28.37972  ? 121 LEU A CD2  1 
ATOM   1872 H  H    . LEU A 1 121 ? 27.91200  -21.63300 -34.48000 1.000 32.14000  ? 121 LEU A H    1 
ATOM   1873 H  HA   . LEU A 1 121 ? 26.55000  -19.75600 -33.34800 1.000 34.57000  ? 121 LEU A HA   1 
ATOM   1874 H  HB2  . LEU A 1 121 ? 28.87200  -21.04000 -32.43300 1.000 31.07000  ? 121 LEU A HB2  1 
ATOM   1875 H  HB3  . LEU A 1 121 ? 28.07600  -20.00100 -31.53100 1.000 31.07000  ? 121 LEU A HB3  1 
ATOM   1876 H  HG   . LEU A 1 121 ? 26.95600  -22.45700 -32.35100 1.000 35.22000  ? 121 LEU A HG   1 
ATOM   1877 H  HD11 . LEU A 1 121 ? 27.43900  -23.35400 -30.34600 1.000 38.24000  ? 121 LEU A HD11 1 
ATOM   1878 H  HD12 . LEU A 1 121 ? 28.80400  -22.75700 -30.89700 1.000 38.24000  ? 121 LEU A HD12 1 
ATOM   1879 H  HD13 . LEU A 1 121 ? 27.98000  -21.96700 -29.79200 1.000 38.24000  ? 121 LEU A HD13 1 
ATOM   1880 H  HD21 . LEU A 1 121 ? 25.36800  -21.93600 -30.64900 1.000 34.06000  ? 121 LEU A HD21 1 
ATOM   1881 H  HD22 . LEU A 1 121 ? 26.07800  -20.52700 -30.46600 1.000 34.06000  ? 121 LEU A HD22 1 
ATOM   1882 H  HD23 . LEU A 1 121 ? 25.33700  -20.87200 -31.82800 1.000 34.06000  ? 121 LEU A HD23 1 
ATOM   1883 N  N    . GLN A 1 122 ? 29.37800  -18.75600 -34.42200 1.000 32.51442  ? 122 GLN A N    1 
ATOM   1884 C  CA   . GLN A 1 122 ? 30.19900  -17.57500 -34.64000 1.000 31.14321  ? 122 GLN A CA   1 
ATOM   1885 C  C    . GLN A 1 122 ? 29.62600  -16.63600 -35.68700 1.000 32.79341  ? 122 GLN A C    1 
ATOM   1886 O  O    . GLN A 1 122 ? 30.24800  -15.60500 -35.97800 1.000 32.66444  ? 122 GLN A O    1 
ATOM   1887 C  CB   . GLN A 1 122 ? 31.60600  -18.00800 -35.03400 1.000 28.96137  ? 122 GLN A CB   1 
ATOM   1888 C  CG   . GLN A 1 122 ? 32.32700  -18.76700 -33.92400 1.000 27.55857  ? 122 GLN A CG   1 
ATOM   1889 C  CD   . GLN A 1 122 ? 33.55100  -19.49000 -34.45400 1.000 26.79532  ? 122 GLN A CD   1 
ATOM   1890 O  OE1  . GLN A 1 122 ? 34.60800  -18.88900 -34.61900 1.000 28.44552  ? 122 GLN A OE1  1 
ATOM   1891 N  NE2  . GLN A 1 122 ? 33.40600  -20.77800 -34.73600 1.000 29.18245  ? 122 GLN A NE2  1 
ATOM   1892 H  H    . GLN A 1 122 ? 29.67900  -19.47300 -34.79000 1.000 39.02000  ? 122 GLN A H    1 
ATOM   1893 H  HA   . GLN A 1 122 ? 30.26000  -17.07300 -33.81200 1.000 37.37000  ? 122 GLN A HA   1 
ATOM   1894 H  HB2  . GLN A 1 122 ? 31.55200  -18.58900 -35.80800 1.000 34.76000  ? 122 GLN A HB2  1 
ATOM   1895 H  HB3  . GLN A 1 122 ? 32.13000  -17.21900 -35.24700 1.000 34.76000  ? 122 GLN A HB3  1 
ATOM   1896 H  HG2  . GLN A 1 122 ? 32.61400  -18.14100 -33.24100 1.000 33.07000  ? 122 GLN A HG2  1 
ATOM   1897 H  HG3  . GLN A 1 122 ? 31.72600  -19.42400 -33.54100 1.000 33.07000  ? 122 GLN A HG3  1 
ATOM   1898 H  HE21 . GLN A 1 122 ? 32.64600  -21.16200 -34.61500 1.000 35.02000  ? 122 GLN A HE21 1 
ATOM   1899 H  HE22 . GLN A 1 122 ? 34.07300  -21.23000 -35.03900 1.000 35.02000  ? 122 GLN A HE22 1 
ATOM   1900 N  N    . GLN A 1 123 ? 28.45700  -16.95900 -36.24300 1.000 29.51933  ? 123 GLN A N    1 
ATOM   1901 C  CA   . GLN A 1 123 ? 27.80100  -16.11000 -37.21400 1.000 28.87451  ? 123 GLN A CA   1 
ATOM   1902 C  C    . GLN A 1 123 ? 26.42100  -15.63300 -36.79300 1.000 31.46430  ? 123 GLN A C    1 
ATOM   1903 O  O    . GLN A 1 123 ? 25.78400  -14.91800 -37.56700 1.000 30.32732  ? 123 GLN A O    1 
ATOM   1904 C  CB   . GLN A 1 123 ? 27.68600  -16.85500 -38.55200 1.000 28.20338  ? 123 GLN A CB   1 
ATOM   1905 C  CG   . GLN A 1 123 ? 29.02600  -17.26200 -39.10000 1.000 31.49062  ? 123 GLN A CG   1 
ATOM   1906 C  CD   . GLN A 1 123 ? 28.89100  -18.13500 -40.30000 1.000 30.31679  ? 123 GLN A CD   1 
ATOM   1907 O  OE1  . GLN A 1 123 ? 28.48900  -17.68300 -41.38700 1.000 30.81159  ? 123 GLN A OE1  1 
ATOM   1908 N  NE2  . GLN A 1 123 ? 29.21100  -19.41000 -40.12800 1.000 28.76661  ? 123 GLN A NE2  1 
ATOM   1909 H  H    . GLN A 1 123 ? 28.02300  -17.68000 -36.06500 1.000 35.42000  ? 123 GLN A H    1 
ATOM   1910 H  HA   . GLN A 1 123 ? 28.34700  -15.31900 -37.34000 1.000 34.65000  ? 123 GLN A HA   1 
ATOM   1911 H  HB2  . GLN A 1 123 ? 27.15700  -17.65800 -38.42400 1.000 33.84000  ? 123 GLN A HB2  1 
ATOM   1912 H  HB3  . GLN A 1 123 ? 27.25800  -16.27600 -39.20200 1.000 33.84000  ? 123 GLN A HB3  1 
ATOM   1913 H  HG2  . GLN A 1 123 ? 29.52100  -16.46800 -39.35600 1.000 37.79000  ? 123 GLN A HG2  1 
ATOM   1914 H  HG3  . GLN A 1 123 ? 29.51400  -17.75200 -38.42000 1.000 37.79000  ? 123 GLN A HG3  1 
ATOM   1915 H  HE21 . GLN A 1 123 ? 29.47800  -19.68600 -39.35800 1.000 34.52000  ? 123 GLN A HE21 1 
ATOM   1916 H  HE22 . GLN A 1 123 ? 29.15200  -19.96100 -40.78600 1.000 34.52000  ? 123 GLN A HE22 1 
ATOM   1917 N  N    . ILE A 1 124 ? 25.94500  -15.98500 -35.59700 1.000 31.92225  ? 124 ILE A N    1 
ATOM   1918 C  CA   . ILE A 1 124 ? 24.63600  -15.53400 -35.13900 1.000 31.46956  ? 124 ILE A CA   1 
ATOM   1919 C  C    . ILE A 1 124 ? 24.80300  -14.89200 -33.77100 1.000 30.96161  ? 124 ILE A C    1 
ATOM   1920 O  O    . ILE A 1 124 ? 25.72200  -15.22600 -33.01900 1.000 32.42757  ? 124 ILE A O    1 
ATOM   1921 C  CB   . ILE A 1 124 ? 23.59800  -16.67700 -35.08300 1.000 29.87990  ? 124 ILE A CB   1 
ATOM   1922 C  CG1  . ILE A 1 124 ? 24.02300  -17.76400 -34.10300 1.000 32.30651  ? 124 ILE A CG1  1 
ATOM   1923 C  CG2  . ILE A 1 124 ? 23.38800  -17.26400 -36.46900 1.000 32.14859  ? 124 ILE A CG2  1 
ATOM   1924 C  CD1  . ILE A 1 124 ? 22.96700  -18.82600 -33.88300 1.000 33.64088  ? 124 ILE A CD1  1 
ATOM   1925 H  H    . ILE A 1 124 ? 26.36300  -16.48500 -35.03600 1.000 38.31000  ? 124 ILE A H    1 
ATOM   1926 H  HA   . ILE A 1 124 ? 24.30000  -14.86600 -35.75700 1.000 37.76000  ? 124 ILE A HA   1 
ATOM   1927 H  HB   . ILE A 1 124 ? 22.76100  -16.30300 -34.76700 1.000 35.85000  ? 124 ILE A HB   1 
ATOM   1928 H  HG12 . ILE A 1 124 ? 24.81700  -18.20200 -34.44600 1.000 38.77000  ? 124 ILE A HG12 1 
ATOM   1929 H  HG13 . ILE A 1 124 ? 24.21400  -17.35400 -33.24500 1.000 38.77000  ? 124 ILE A HG13 1 
ATOM   1930 H  HG21 . ILE A 1 124 ? 22.64400  -17.88500 -36.44000 1.000 38.58000  ? 124 ILE A HG21 1 
ATOM   1931 H  HG22 . ILE A 1 124 ? 23.19400  -16.54500 -37.09100 1.000 38.58000  ? 124 ILE A HG22 1 
ATOM   1932 H  HG23 . ILE A 1 124 ? 24.19500  -17.72800 -36.74100 1.000 38.58000  ? 124 ILE A HG23 1 
ATOM   1933 H  HD11 . ILE A 1 124 ? 23.25000  -19.40700 -33.16000 1.000 40.37000  ? 124 ILE A HD11 1 
ATOM   1934 H  HD12 . ILE A 1 124 ? 22.12900  -18.39500 -33.65200 1.000 40.37000  ? 124 ILE A HD12 1 
ATOM   1935 H  HD13 . ILE A 1 124 ? 22.86100  -19.33900 -34.69900 1.000 40.37000  ? 124 ILE A HD13 1 
ATOM   1936 N  N    . GLU A 1 125 ? 23.91700  -13.95200 -33.45600 1.000 33.19872  ? 125 GLU A N    1 
ATOM   1937 C  CA   . GLU A 1 125 ? 23.97300  -13.25200 -32.17800 1.000 32.15912  ? 125 GLU A CA   1 
ATOM   1938 C  C    . GLU A 1 125 ? 23.33100  -14.12200 -31.10400 1.000 35.83061  ? 125 GLU A C    1 
ATOM   1939 O  O    . GLU A 1 125 ? 22.11100  -14.31600 -31.09200 1.000 33.83564  ? 125 GLU A O    1 
ATOM   1940 C  CB   . GLU A 1 125 ? 23.27400  -11.90000 -32.27700 1.000 37.27026  ? 125 GLU A CB   1 
ATOM   1941 C  CG   . GLU A 1 125 ? 23.24400  -11.13800 -30.96200 1.000 48.10050  ? 125 GLU A CG   1 
ATOM   1942 C  CD   . GLU A 1 125 ? 22.41800  -9.87000  -31.03500 1.000 54.80394  ? 125 GLU A CD   1 
ATOM   1943 O  OE1  . GLU A 1 125 ? 22.50600  -9.15300  -32.05500 1.000 49.71122  ? 125 GLU A OE1  1 
ATOM   1944 O  OE2  . GLU A 1 125 ? 21.67600  -9.60400  -30.07200 1.000 59.24921  ? 125 GLU A OE2  1 
ATOM   1945 H  H    . GLU A 1 125 ? 23.27300  -13.70100 -33.96800 1.000 39.84000  ? 125 GLU A H    1 
ATOM   1946 H  HA   . GLU A 1 125 ? 24.90000  -13.10000 -31.93800 1.000 38.59000  ? 125 GLU A HA   1 
ATOM   1947 H  HB2  . GLU A 1 125 ? 23.74100  -11.35300 -32.92800 1.000 44.72000  ? 125 GLU A HB2  1 
ATOM   1948 H  HB3  . GLU A 1 125 ? 22.35700  -12.04100 -32.56000 1.000 44.72000  ? 125 GLU A HB3  1 
ATOM   1949 H  HG2  . GLU A 1 125 ? 22.86000  -11.70600 -30.27600 1.000 57.72000  ? 125 GLU A HG2  1 
ATOM   1950 H  HG3  . GLU A 1 125 ? 24.15000  -10.89200 -30.72000 1.000 57.72000  ? 125 GLU A HG3  1 
ATOM   1951 N  N    . LEU A 1 126 ? 24.14600  -14.61500 -30.17800 1.000 33.54086  ? 126 LEU A N    1 
ATOM   1952 C  CA   . LEU A 1 126 ? 23.67500  -15.52100 -29.14200 1.000 34.59889  ? 126 LEU A CA   1 
ATOM   1953 C  C    . LEU A 1 126 ? 24.58500  -15.38600 -27.93400 1.000 36.66229  ? 126 LEU A C    1 
ATOM   1954 O  O    . LEU A 1 126 ? 25.80700  -15.44300 -28.07500 1.000 37.17814  ? 126 LEU A O    1 
ATOM   1955 C  CB   . LEU A 1 126 ? 23.66300  -16.96100 -29.65800 1.000 32.63023  ? 126 LEU A CB   1 
ATOM   1956 C  CG   . LEU A 1 126 ? 23.03100  -17.97500 -28.72800 1.000 35.31476  ? 126 LEU A CG   1 
ATOM   1957 C  CD1  . LEU A 1 126 ? 21.51400  -17.95100 -28.91700 1.000 39.79951  ? 126 LEU A CD1  1 
ATOM   1958 C  CD2  . LEU A 1 126 ? 23.53200  -19.38000 -28.94100 1.000 36.40700  ? 126 LEU A CD2  1 
ATOM   1959 H  H    . LEU A 1 126 ? 24.98600  -14.43700 -30.12900 1.000 40.25000  ? 126 LEU A H    1 
ATOM   1960 H  HA   . LEU A 1 126 ? 22.77500  -15.28500 -28.86900 1.000 41.52000  ? 126 LEU A HA   1 
ATOM   1961 H  HB2  . LEU A 1 126 ? 23.16600  -16.98300 -30.49100 1.000 39.16000  ? 126 LEU A HB2  1 
ATOM   1962 H  HB3  . LEU A 1 126 ? 24.57900  -17.23800 -29.81100 1.000 39.16000  ? 126 LEU A HB3  1 
ATOM   1963 H  HG   . LEU A 1 126 ? 23.27600  -17.72800 -27.82200 1.000 42.38000  ? 126 LEU A HG   1 
ATOM   1964 H  HD11 . LEU A 1 126 ? 21.11400  -18.62000 -28.34000 1.000 47.76000  ? 126 LEU A HD11 1 
ATOM   1965 H  HD12 . LEU A 1 126 ? 21.18100  -17.07100 -28.68400 1.000 47.76000  ? 126 LEU A HD12 1 
ATOM   1966 H  HD13 . LEU A 1 126 ? 21.30900  -18.14900 -29.84400 1.000 47.76000  ? 126 LEU A HD13 1 
ATOM   1967 H  HD21 . LEU A 1 126 ? 23.14700  -19.95900 -28.26400 1.000 43.69000  ? 126 LEU A HD21 1 
ATOM   1968 H  HD22 . LEU A 1 126 ? 23.26400  -19.68100 -29.82300 1.000 43.69000  ? 126 LEU A HD22 1 
ATOM   1969 H  HD23 . LEU A 1 126 ? 24.50000  -19.38500 -28.86900 1.000 43.69000  ? 126 LEU A HD23 1 
ATOM   1970 N  N    . LYS A 1 127 ? 23.99500  -15.20200 -26.75900 1.000 33.45401  ? 127 LYS A N    1 
ATOM   1971 C  CA   . LYS A 1 127 ? 24.74700  -15.18000 -25.51600 1.000 33.96197  ? 127 LYS A CA   1 
ATOM   1972 C  C    . LYS A 1 127 ? 24.28200  -16.34500 -24.65900 1.000 29.55091  ? 127 LYS A C    1 
ATOM   1973 O  O    . LYS A 1 127 ? 23.08100  -16.60400 -24.52800 1.000 33.21188  ? 127 LYS A O    1 
ATOM   1974 C  CB   . LYS A 1 127 ? 24.57400  -13.84500 -24.78600 1.000 38.19932  ? 127 LYS A CB   1 
ATOM   1975 C  CG   . LYS A 1 127 ? 25.44600  -12.74700 -25.41300 1.000 48.13472  ? 127 LYS A CG   1 
ATOM   1976 C  CD   . LYS A 1 127 ? 25.07400  -11.35100 -24.94600 1.000 74.03519  ? 127 LYS A CD   1 
ATOM   1977 C  CE   . LYS A 1 127 ? 25.20100  -10.30700 -26.06900 1.000 97.00110  ? 127 LYS A CE   1 
ATOM   1978 N  NZ   . LYS A 1 127 ? 24.46300  -10.64700 -27.32800 1.000 80.56755  ? 127 LYS A NZ   1 
ATOM   1979 H  H    . LYS A 1 127 ? 23.14900  -15.08600 -26.65700 1.000 40.14000  ? 127 LYS A H    1 
ATOM   1980 H  HA   . LYS A 1 127 ? 25.69600  -15.28600 -25.68400 1.000 40.76000  ? 127 LYS A HA   1 
ATOM   1981 H  HB2  . LYS A 1 127 ? 23.64700  -13.56800 -24.84000 1.000 45.84000  ? 127 LYS A HB2  1 
ATOM   1982 H  HB3  . LYS A 1 127 ? 24.83600  -13.95100 -23.85800 1.000 45.84000  ? 127 LYS A HB3  1 
ATOM   1983 H  HG2  . LYS A 1 127 ? 26.37300  -12.90400 -25.17300 1.000 57.76000  ? 127 LYS A HG2  1 
ATOM   1984 H  HG3  . LYS A 1 127 ? 25.34300  -12.77500 -26.37700 1.000 57.76000  ? 127 LYS A HG3  1 
ATOM   1985 H  HD2  . LYS A 1 127 ? 24.15500  -11.35200 -24.63800 1.000 88.84000  ? 127 LYS A HD2  1 
ATOM   1986 H  HD3  . LYS A 1 127 ? 25.66600  -11.08900 -24.22300 1.000 88.84000  ? 127 LYS A HD3  1 
ATOM   1987 H  HE2  . LYS A 1 127 ? 24.85200  -9.46200  -25.74600 1.000 116.40000 ? 127 LYS A HE2  1 
ATOM   1988 H  HE3  . LYS A 1 127 ? 26.13900  -10.21300 -26.29800 1.000 116.40000 ? 127 LYS A HE3  1 
ATOM   1989 H  HZ1  . LYS A 1 127 ? 24.49600  -9.96100  -27.89400 1.000 96.68000  ? 127 LYS A HZ1  1 
ATOM   1990 H  HZ2  . LYS A 1 127 ? 24.83300  -11.35800 -27.71500 1.000 96.68000  ? 127 LYS A HZ2  1 
ATOM   1991 H  HZ3  . LYS A 1 127 ? 23.61200  -10.82800 -27.14300 1.000 96.68000  ? 127 LYS A HZ3  1 
ATOM   1992 N  N    . PHE A 1 128 ? 25.24000  -17.04500 -24.07800 1.000 30.70105  ? 128 PHE A N    1 
ATOM   1993 C  CA   . PHE A 1 128 ? 24.94500  -18.19200 -23.23400 1.000 27.26380  ? 128 PHE A CA   1 
ATOM   1994 C  C    . PHE A 1 128 ? 24.66700  -17.75100 -21.80200 1.000 30.71158  ? 128 PHE A C    1 
ATOM   1995 O  O    . PHE A 1 128 ? 25.11700  -16.69300 -21.35600 1.000 32.48547  ? 128 PHE A O    1 
ATOM   1996 C  CB   . PHE A 1 128 ? 26.11200  -19.17200 -23.25500 1.000 27.86650  ? 128 PHE A CB   1 
ATOM   1997 C  CG   . PHE A 1 128 ? 26.25100  -19.90200 -24.55200 1.000 27.76912  ? 128 PHE A CG   1 
ATOM   1998 C  CD1  . PHE A 1 128 ? 25.30000  -20.82100 -24.94500 1.000 28.86925  ? 128 PHE A CD1  1 
ATOM   1999 C  CD2  . PHE A 1 128 ? 27.32500  -19.65900 -25.37900 1.000 29.22719  ? 128 PHE A CD2  1 
ATOM   2000 C  CE1  . PHE A 1 128 ? 25.42800  -21.49400 -26.15100 1.000 32.60654  ? 128 PHE A CE1  1 
ATOM   2001 C  CE2  . PHE A 1 128 ? 27.44700  -20.33500 -26.58500 1.000 30.04044  ? 128 PHE A CE2  1 
ATOM   2002 C  CZ   . PHE A 1 128 ? 26.49900  -21.25000 -26.95200 1.000 27.84808  ? 128 PHE A CZ   1 
ATOM   2003 H  H    . PHE A 1 128 ? 26.07900  -16.87600 -24.15800 1.000 36.84000  ? 128 PHE A H    1 
ATOM   2004 H  HA   . PHE A 1 128 ? 24.15400  -18.64500 -23.56600 1.000 32.72000  ? 128 PHE A HA   1 
ATOM   2005 H  HB2  . PHE A 1 128 ? 26.93500  -18.68200 -23.09900 1.000 33.44000  ? 128 PHE A HB2  1 
ATOM   2006 H  HB3  . PHE A 1 128 ? 25.98000  -19.83100 -22.55600 1.000 33.44000  ? 128 PHE A HB3  1 
ATOM   2007 H  HD1  . PHE A 1 128 ? 24.56800  -20.99200 -24.39700 1.000 34.64000  ? 128 PHE A HD1  1 
ATOM   2008 H  HD2  . PHE A 1 128 ? 27.97100  -19.03900 -25.12800 1.000 35.07000  ? 128 PHE A HD2  1 
ATOM   2009 H  HE1  . PHE A 1 128 ? 24.78200  -22.11000 -26.41200 1.000 39.13000  ? 128 PHE A HE1  1 
ATOM   2010 H  HE2  . PHE A 1 128 ? 28.17200  -20.16600 -27.14300 1.000 36.05000  ? 128 PHE A HE2  1 
ATOM   2011 H  HZ   . PHE A 1 128 ? 26.58800  -21.71000 -27.75600 1.000 33.42000  ? 128 PHE A HZ   1 
ATOM   2012 N  N    . ASN A 1 129 ? 23.89500  -18.57200 -21.09300 1.000 29.00348  ? 129 ASN A N    1 
ATOM   2013 C  CA   . ASN A 1 129 ? 23.57200  -18.29100 -19.70200 1.000 28.29550  ? 129 ASN A CA   1 
ATOM   2014 C  C    . ASN A 1 129 ? 24.57400  -18.90100 -18.72800 1.000 30.71947  ? 129 ASN A C    1 
ATOM   2015 O  O    . ASN A 1 129 ? 25.03200  -18.20400 -17.80800 1.000 30.83791  ? 129 ASN A O    1 
ATOM   2016 C  CB   . ASN A 1 129 ? 22.15000  -18.75800 -19.36200 1.000 35.67533  ? 129 ASN A CB   1 
ATOM   2017 C  CG   . ASN A 1 129 ? 21.05300  -17.90400 -20.00400 1.000 41.93661  ? 129 ASN A CG   1 
ATOM   2018 O  OD1  . ASN A 1 129 ? 21.21600  -16.69000 -20.23200 1.000 39.21786  ? 129 ASN A OD1  1 
ATOM   2019 N  ND2  . ASN A 1 129 ? 19.91000  -18.52700 -20.26400 1.000 43.92632  ? 129 ASN A ND2  1 
ATOM   2020 H  H    . ASN A 1 129 ? 23.54800  -19.29800 -21.39700 1.000 34.81000  ? 129 ASN A H    1 
ATOM   2021 H  HA   . ASN A 1 129 ? 23.62500  -17.32900 -19.58800 1.000 33.95000  ? 129 ASN A HA   1 
ATOM   2022 H  HB2  . ASN A 1 129 ? 22.03700  -19.66900 -19.67400 1.000 42.81000  ? 129 ASN A HB2  1 
ATOM   2023 H  HB3  . ASN A 1 129 ? 22.03000  -18.71900 -18.40000 1.000 42.81000  ? 129 ASN A HB3  1 
ATOM   2024 H  HD21 . ASN A 1 129 ? 19.82100  -19.36000 -20.07100 1.000 52.71000  ? 129 ASN A HD21 1 
ATOM   2025 H  HD22 . ASN A 1 129 ? 19.25800  -18.09700 -20.62400 1.000 52.71000  ? 129 ASN A HD22 1 
ATOM   2026 N  N    . PRO A 1 130 ? 24.91700  -20.18000 -18.82800 1.000 30.30627  ? 130 PRO A N    1 
ATOM   2027 C  CA   . PRO A 1 130 ? 25.86800  -20.74700 -17.85000 1.000 27.86124  ? 130 PRO A CA   1 
ATOM   2028 C  C    . PRO A 1 130 ? 27.23400  -20.11200 -18.00500 1.000 29.16139  ? 130 PRO A C    1 
ATOM   2029 O  O    . PRO A 1 130 ? 27.76400  -20.01800 -19.12500 1.000 25.90574  ? 130 PRO A O    1 
ATOM   2030 C  CB   . PRO A 1 130 ? 25.90600  -22.24700 -18.18900 1.000 29.65882  ? 130 PRO A CB   1 
ATOM   2031 C  CG   . PRO A 1 130 ? 24.70500  -22.49300 -19.05600 1.000 31.03530  ? 130 PRO A CG   1 
ATOM   2032 C  CD   . PRO A 1 130 ? 24.47200  -21.19500 -19.80300 1.000 32.00384  ? 130 PRO A CD   1 
ATOM   2033 H  HA   . PRO A 1 130 ? 25.54200  -20.63200 -16.94400 1.000 33.43000  ? 130 PRO A HA   1 
ATOM   2034 H  HB2  . PRO A 1 130 ? 26.72500  -22.45500 -18.66500 1.000 35.59000  ? 130 PRO A HB2  1 
ATOM   2035 H  HB3  . PRO A 1 130 ? 25.85600  -22.76900 -17.37300 1.000 35.59000  ? 130 PRO A HB3  1 
ATOM   2036 H  HG2  . PRO A 1 130 ? 24.88900  -23.21800 -19.67400 1.000 37.24000  ? 130 PRO A HG2  1 
ATOM   2037 H  HG3  . PRO A 1 130 ? 23.94000  -22.71500 -18.50300 1.000 37.24000  ? 130 PRO A HG3  1 
ATOM   2038 H  HD2  . PRO A 1 130 ? 25.00500  -21.15800 -20.61200 1.000 38.41000  ? 130 PRO A HD2  1 
ATOM   2039 H  HD3  . PRO A 1 130 ? 23.53300  -21.08200 -20.01900 1.000 38.41000  ? 130 PRO A HD3  1 
ATOM   2040 N  N    . PRO A 1 131 ? 27.81600  -19.63600 -16.91200 1.000 27.16905  ? 131 PRO A N    1 
ATOM   2041 C  CA   . PRO A 1 131 ? 29.20200  -19.14300 -16.97700 1.000 29.25614  ? 131 PRO A CA   1 
ATOM   2042 C  C    . PRO A 1 131 ? 30.14600  -20.11300 -17.66600 1.000 27.68227  ? 131 PRO A C    1 
ATOM   2043 O  O    . PRO A 1 131 ? 31.05500  -19.67900 -18.38600 1.000 28.07705  ? 131 PRO A O    1 
ATOM   2044 C  CB   . PRO A 1 131 ? 29.55300  -18.92800 -15.49900 1.000 29.14823  ? 131 PRO A CB   1 
ATOM   2045 C  CG   . PRO A 1 131 ? 28.25300  -18.52000 -14.89300 1.000 28.64817  ? 131 PRO A CG   1 
ATOM   2046 C  CD   . PRO A 1 131 ? 27.20600  -19.38400 -15.58500 1.000 28.39814  ? 131 PRO A CD   1 
ATOM   2047 H  HA   . PRO A 1 131 ? 29.23700  -18.28900 -17.43600 1.000 35.11000  ? 131 PRO A HA   1 
ATOM   2048 H  HB2  . PRO A 1 131 ? 29.88300  -19.75200 -15.10700 1.000 34.98000  ? 131 PRO A HB2  1 
ATOM   2049 H  HB3  . PRO A 1 131 ? 30.22000  -18.22800 -15.41000 1.000 34.98000  ? 131 PRO A HB3  1 
ATOM   2050 H  HG2  . PRO A 1 131 ? 28.26600  -18.68900 -13.93800 1.000 34.38000  ? 131 PRO A HG2  1 
ATOM   2051 H  HG3  . PRO A 1 131 ? 28.09100  -17.57900 -15.06100 1.000 34.38000  ? 131 PRO A HG3  1 
ATOM   2052 H  HD2  . PRO A 1 131 ? 27.06700  -20.21400 -15.10300 1.000 34.08000  ? 131 PRO A HD2  1 
ATOM   2053 H  HD3  . PRO A 1 131 ? 26.36600  -18.90700 -15.67300 1.000 34.08000  ? 131 PRO A HD3  1 
ATOM   2054 N  N    . ALA A 1 132 ? 29.94700  -21.41800 -17.47800 1.000 27.43750  ? 132 ALA A N    1 
ATOM   2055 C  CA   . ALA A 1 132 ? 30.82100  -22.39400 -18.12400 1.000 23.70811  ? 132 ALA A CA   1 
ATOM   2056 C  C    . ALA A 1 132 ? 30.80600  -22.22500 -19.64000 1.000 27.07430  ? 132 ALA A C    1 
ATOM   2057 O  O    . ALA A 1 132 ? 31.85600  -22.25200 -20.29500 1.000 27.60594  ? 132 ALA A O    1 
ATOM   2058 C  CB   . ALA A 1 132 ? 30.39000  -23.81300 -17.74800 1.000 27.78228  ? 132 ALA A CB   1 
ATOM   2059 H  H    . ALA A 1 132 ? 29.32400  -21.75800 -16.99100 1.000 32.93000  ? 132 ALA A H    1 
ATOM   2060 H  HA   . ALA A 1 132 ? 31.72800  -22.25700 -17.80900 1.000 28.45000  ? 132 ALA A HA   1 
ATOM   2061 H  HB1  . ALA A 1 132 ? 31.02700  -24.44500 -18.11500 1.000 33.34000  ? 132 ALA A HB1  1 
ATOM   2062 H  HB2  . ALA A 1 132 ? 30.36700  -23.89100 -16.78100 1.000 33.34000  ? 132 ALA A HB2  1 
ATOM   2063 H  HB3  . ALA A 1 132 ? 29.50800  -23.98300 -18.11300 1.000 33.34000  ? 132 ALA A HB3  1 
ATOM   2064 N  N    . LEU A 1 133 ? 29.62900  -22.02900 -20.20900 1.000 27.59541  ? 133 LEU A N    1 
ATOM   2065 C  CA   . LEU A 1 133 ? 29.54700  -21.86400 -21.65600 1.000 24.62401  ? 133 LEU A CA   1 
ATOM   2066 C  C    . LEU A 1 133 ? 30.03000  -20.48300 -22.08700 1.000 28.45078  ? 133 LEU A C    1 
ATOM   2067 O  O    . LEU A 1 133 ? 30.71100  -20.35200 -23.11000 1.000 29.14560  ? 133 LEU A O    1 
ATOM   2068 C  CB   . LEU A 1 133 ? 28.11100  -22.10500 -22.11400 1.000 25.47411  ? 133 LEU A CB   1 
ATOM   2069 C  CG   . LEU A 1 133 ? 27.61900  -23.54300 -22.13100 1.000 27.46645  ? 133 LEU A CG   1 
ATOM   2070 C  CD1  . LEU A 1 133 ? 26.17000  -23.60900 -22.52200 1.000 28.93768  ? 133 LEU A CD1  1 
ATOM   2071 C  CD2  . LEU A 1 133 ? 28.44700  -24.37900 -23.10900 1.000 27.16905  ? 133 LEU A CD2  1 
ATOM   2072 H  H    . LEU A 1 133 ? 28.87700  -21.98800 -19.79300 1.000 33.12000  ? 133 LEU A H    1 
ATOM   2073 H  HA   . LEU A 1 133 ? 30.11500  -22.52100 -22.08900 1.000 29.55000  ? 133 LEU A HA   1 
ATOM   2074 H  HB2  . LEU A 1 133 ? 27.52300  -21.61300 -21.51900 1.000 30.57000  ? 133 LEU A HB2  1 
ATOM   2075 H  HB3  . LEU A 1 133 ? 28.02600  -21.76700 -23.01900 1.000 30.57000  ? 133 LEU A HB3  1 
ATOM   2076 H  HG   . LEU A 1 133 ? 27.71600  -23.91000 -21.23800 1.000 32.96000  ? 133 LEU A HG   1 
ATOM   2077 H  HD11 . LEU A 1 133 ? 25.87700  -24.53300 -22.49400 1.000 34.73000  ? 133 LEU A HD11 1 
ATOM   2078 H  HD12 . LEU A 1 133 ? 25.65000  -23.07800 -21.89900 1.000 34.73000  ? 133 LEU A HD12 1 
ATOM   2079 H  HD13 . LEU A 1 133 ? 26.06900  -23.25700 -23.42000 1.000 34.73000  ? 133 LEU A HD13 1 
ATOM   2080 H  HD21 . LEU A 1 133 ? 28.01800  -25.24100 -23.23000 1.000 32.60000  ? 133 LEU A HD21 1 
ATOM   2081 H  HD22 . LEU A 1 133 ? 28.49700  -23.91300 -23.95900 1.000 32.60000  ? 133 LEU A HD22 1 
ATOM   2082 H  HD23 . LEU A 1 133 ? 29.33700  -24.50100 -22.74500 1.000 32.60000  ? 133 LEU A HD23 1 
ATOM   2083 N  N    . GLN A 1 134 ? 29.71500  -19.44300 -21.31900 1.000 27.92177  ? 134 GLN A N    1 
ATOM   2084 C  CA   . GLN A 1 134 ? 30.26900  -18.12300 -21.61100 1.000 30.08782  ? 134 GLN A CA   1 
ATOM   2085 C  C    . GLN A 1 134 ? 31.79400  -18.16800 -21.67100 1.000 30.70631  ? 134 GLN A C    1 
ATOM   2086 O  O    . GLN A 1 134 ? 32.41700  -17.64400 -22.60200 1.000 29.07191  ? 134 GLN A O    1 
ATOM   2087 C  CB   . GLN A 1 134 ? 29.84300  -17.11300 -20.54500 1.000 31.53273  ? 134 GLN A CB   1 
ATOM   2088 C  CG   . GLN A 1 134 ? 28.35300  -16.88400 -20.41100 1.000 29.30088  ? 134 GLN A CG   1 
ATOM   2089 C  CD   . GLN A 1 134 ? 28.03000  -15.98800 -19.21600 1.000 34.70679  ? 134 GLN A CD   1 
ATOM   2090 O  OE1  . GLN A 1 134 ? 28.92800  -15.48000 -18.55400 1.000 42.77881  ? 134 GLN A OE1  1 
ATOM   2091 N  NE2  . GLN A 1 134 ? 26.75300  -15.83800 -18.90700 1.000 39.22839  ? 134 GLN A NE2  1 
ATOM   2092 H  H    . GLN A 1 134 ? 29.19400  -19.47400 -20.63500 1.000 33.50000  ? 134 GLN A H    1 
ATOM   2093 H  HA   . GLN A 1 134 ? 29.91900  -17.83700 -22.46900 1.000 36.10000  ? 134 GLN A HA   1 
ATOM   2094 H  HB2  . GLN A 1 134 ? 30.16400  -17.42600 -19.68500 1.000 37.84000  ? 134 GLN A HB2  1 
ATOM   2095 H  HB3  . GLN A 1 134 ? 30.24700  -16.25700 -20.75900 1.000 37.84000  ? 134 GLN A HB3  1 
ATOM   2096 H  HG2  . GLN A 1 134 ? 28.02100  -16.45300 -21.21400 1.000 35.16000  ? 134 GLN A HG2  1 
ATOM   2097 H  HG3  . GLN A 1 134 ? 27.90700  -17.73600 -20.28300 1.000 35.16000  ? 134 GLN A HG3  1 
ATOM   2098 H  HE21 . GLN A 1 134 ? 26.14800  -16.23500 -19.37200 1.000 47.08000  ? 134 GLN A HE21 1 
ATOM   2099 H  HE22 . GLN A 1 134 ? 26.52700  -15.34200 -18.24100 1.000 47.08000  ? 134 GLN A HE22 1 
ATOM   2100 N  N    . ASP A 1 135 ? 32.41500  -18.74700 -20.64300 1.000 27.90071  ? 135 ASP A N    1 
ATOM   2101 C  CA   . ASP A 1 135 ? 33.87100  -18.73400 -20.55200 1.000 26.71373  ? 135 ASP A CA   1 
ATOM   2102 C  C    . ASP A 1 135 ? 34.48300  -19.57600 -21.66000 1.000 29.29299  ? 135 ASP A C    1 
ATOM   2103 O  O    . ASP A 1 135 ? 35.46800  -19.17100 -22.29300 1.000 31.11162  ? 135 ASP A O    1 
ATOM   2104 C  CB   . ASP A 1 135 ? 34.34600  -19.26900 -19.19800 1.000 30.49576  ? 135 ASP A CB   1 
ATOM   2105 C  CG   . ASP A 1 135 ? 33.95300  -18.37900 -18.02900 1.000 32.95921  ? 135 ASP A CG   1 
ATOM   2106 O  OD1  . ASP A 1 135 ? 33.59100  -17.20500 -18.25700 1.000 33.28820  ? 135 ASP A OD1  1 
ATOM   2107 O  OD2  . ASP A 1 135 ? 34.02800  -18.83900 -16.85500 1.000 32.88289  ? 135 ASP A OD2  1 
ATOM   2108 H  H    . ASP A 1 135 ? 32.02000  -19.14800 -19.99300 1.000 33.48000  ? 135 ASP A H    1 
ATOM   2109 H  HA   . ASP A 1 135 ? 34.16700  -17.81400 -20.63300 1.000 32.06000  ? 135 ASP A HA   1 
ATOM   2110 H  HB2  . ASP A 1 135 ? 33.95500  -20.14400 -19.05100 1.000 36.59000  ? 135 ASP A HB2  1 
ATOM   2111 H  HB3  . ASP A 1 135 ? 35.31400  -19.33500 -19.20900 1.000 36.59000  ? 135 ASP A HB3  1 
ATOM   2112 N  N    . ALA A 1 136 ? 33.90900  -20.75700 -21.89100 1.000 29.19297  ? 136 ALA A N    1 
ATOM   2113 C  CA   . ALA A 1 136 ? 34.46800  -21.67300 -22.87300 1.000 27.54278  ? 136 ALA A CA   1 
ATOM   2114 C  C    . ALA A 1 136 ? 34.21200  -21.17400 -24.29000 1.000 27.79017  ? 136 ALA A C    1 
ATOM   2115 O  O    . ALA A 1 136 ? 35.05700  -21.34300 -25.16700 1.000 29.23508  ? 136 ALA A O    1 
ATOM   2116 C  CB   . ALA A 1 136 ? 33.87300  -23.06600 -22.69700 1.000 27.10062  ? 136 ALA A CB   1 
ATOM   2117 H  H    . ALA A 1 136 ? 33.20300  -21.04600 -21.49500 1.000 35.03000  ? 136 ALA A H    1 
ATOM   2118 H  HA   . ALA A 1 136 ? 35.42500  -21.73300 -22.73100 1.000 33.05000  ? 136 ALA A HA   1 
ATOM   2119 H  HB1  . ALA A 1 136 ? 34.27000  -23.66400 -23.34900 1.000 32.52000  ? 136 ALA A HB1  1 
ATOM   2120 H  HB2  . ALA A 1 136 ? 34.06500  -23.38100 -21.80000 1.000 32.52000  ? 136 ALA A HB2  1 
ATOM   2121 H  HB3  . ALA A 1 136 ? 32.91300  -23.01900 -22.83200 1.000 32.52000  ? 136 ALA A HB3  1 
ATOM   2122 N  N    . TYR A 1 137 ? 33.04600  -20.57400 -24.53200 1.000 26.22946  ? 137 TYR A N    1 
ATOM   2123 C  CA   . TYR A 1 137 ? 32.77500  -20.03800 -25.86700 1.000 26.79795  ? 137 TYR A CA   1 
ATOM   2124 C  C    . TYR A 1 137 ? 33.74000  -18.91500 -26.21000 1.000 30.10361  ? 137 TYR A C    1 
ATOM   2125 O  O    . TYR A 1 137 ? 34.23400  -18.83500 -27.33900 1.000 29.94043  ? 137 TYR A O    1 
ATOM   2126 C  CB   . TYR A 1 137 ? 31.33300  -19.55100 -25.97200 1.000 28.42709  ? 137 TYR A CB   1 
ATOM   2127 C  CG   . TYR A 1 137 ? 30.98400  -19.11600 -27.38400 1.000 26.64004  ? 137 TYR A CG   1 
ATOM   2128 C  CD1  . TYR A 1 137 ? 31.25600  -19.93100 -28.45700 1.000 31.41692  ? 137 TYR A CD1  1 
ATOM   2129 C  CD2  . TYR A 1 137 ? 30.40100  -17.89100 -27.62700 1.000 31.89330  ? 137 TYR A CD2  1 
ATOM   2130 C  CE1  . TYR A 1 137 ? 30.96700  -19.53600 -29.74200 1.000 28.89820  ? 137 TYR A CE1  1 
ATOM   2131 C  CE2  . TYR A 1 137 ? 30.09200  -17.49400 -28.91100 1.000 36.76230  ? 137 TYR A CE2  1 
ATOM   2132 C  CZ   . TYR A 1 137 ? 30.37800  -18.32500 -29.96100 1.000 34.11198  ? 137 TYR A CZ   1 
ATOM   2133 O  OH   . TYR A 1 137 ? 30.07600  -17.93700 -31.25700 1.000 35.43320  ? 137 TYR A OH   1 
ATOM   2134 H  H    . TYR A 1 137 ? 32.41400  -20.46700 -23.96000 1.000 31.47000  ? 137 TYR A H    1 
ATOM   2135 H  HA   . TYR A 1 137 ? 32.89100  -20.75300 -26.51200 1.000 32.16000  ? 137 TYR A HA   1 
ATOM   2136 H  HB2  . TYR A 1 137 ? 30.73400  -20.27100 -25.71900 1.000 34.11000  ? 137 TYR A HB2  1 
ATOM   2137 H  HB3  . TYR A 1 137 ? 31.20900  -18.79300 -25.38100 1.000 34.11000  ? 137 TYR A HB3  1 
ATOM   2138 H  HD1  . TYR A 1 137 ? 31.64200  -20.76500 -28.31100 1.000 37.70000  ? 137 TYR A HD1  1 
ATOM   2139 H  HD2  . TYR A 1 137 ? 30.21300  -17.32400 -26.91400 1.000 38.27000  ? 137 TYR A HD2  1 
ATOM   2140 H  HE1  . TYR A 1 137 ? 31.17300  -20.09200 -30.45900 1.000 34.68000  ? 137 TYR A HE1  1 
ATOM   2141 H  HE2  . TYR A 1 137 ? 29.69200  -16.66900 -29.06200 1.000 44.11000  ? 137 TYR A HE2  1 
ATOM   2142 H  HH   . TYR A 1 137 ? 29.74100  -17.16700 -31.25600 1.000 42.52000  ? 137 TYR A HH   1 
ATOM   2143 N  N    . TYR A 1 138 ? 34.03300  -18.04000 -25.24900 1.000 30.89055  ? 138 TYR A N    1 
ATOM   2144 C  CA   . TYR A 1 138 ? 35.00500  -16.98100 -25.49000 1.000 30.50366  ? 138 TYR A CA   1 
ATOM   2145 C  C    . TYR A 1 138 ? 36.34800  -17.56900 -25.88900 1.000 31.40640  ? 138 TYR A C    1 
ATOM   2146 O  O    . TYR A 1 138 ? 36.98600  -17.10400 -26.83900 1.000 33.16187  ? 138 TYR A O    1 
ATOM   2147 C  CB   . TYR A 1 138 ? 35.12300  -16.11200 -24.23500 1.000 34.89629  ? 138 TYR A CB   1 
ATOM   2148 C  CG   . TYR A 1 138 ? 36.14100  -15.01200 -24.34100 1.000 39.35735  ? 138 TYR A CG   1 
ATOM   2149 C  CD1  . TYR A 1 138 ? 37.46100  -15.22500 -23.97100 1.000 43.78157  ? 138 TYR A CD1  1 
ATOM   2150 C  CD2  . TYR A 1 138 ? 35.78500  -13.75800 -24.81400 1.000 42.54984  ? 138 TYR A CD2  1 
ATOM   2151 C  CE1  . TYR A 1 138 ? 38.40000  -14.21700 -24.07000 1.000 47.33989  ? 138 TYR A CE1  1 
ATOM   2152 C  CE2  . TYR A 1 138 ? 36.72500  -12.73900 -24.91800 1.000 46.67665  ? 138 TYR A CE2  1 
ATOM   2153 C  CZ   . TYR A 1 138 ? 38.02800  -12.97900 -24.54300 1.000 48.60320  ? 138 TYR A CZ   1 
ATOM   2154 O  OH   . TYR A 1 138 ? 38.96500  -11.97500 -24.64200 1.000 59.72821  ? 138 TYR A OH   1 
ATOM   2155 H  H    . TYR A 1 138 ? 33.68800  -18.03900 -24.46100 1.000 37.07000  ? 138 TYR A H    1 
ATOM   2156 H  HA   . TYR A 1 138 ? 34.70700  -16.41200 -26.21700 1.000 36.60000  ? 138 TYR A HA   1 
ATOM   2157 H  HB2  . TYR A 1 138 ? 34.26300  -15.70000 -24.06100 1.000 41.88000  ? 138 TYR A HB2  1 
ATOM   2158 H  HB3  . TYR A 1 138 ? 35.37800  -16.67700 -23.49000 1.000 41.88000  ? 138 TYR A HB3  1 
ATOM   2159 H  HD1  . TYR A 1 138 ? 37.71700  -16.06000 -23.65100 1.000 51.06000  ? 138 TYR A HD1  1 
ATOM   2160 H  HD2  . TYR A 1 138 ? 34.90400  -13.59600 -25.06400 1.000 52.54000  ? 138 TYR A HD2  1 
ATOM   2161 H  HE1  . TYR A 1 138 ? 39.28200  -14.37400 -23.81800 1.000 56.01000  ? 138 TYR A HE1  1 
ATOM   2162 H  HE2  . TYR A 1 138 ? 36.47600  -11.90200 -25.23900 1.000 56.81000  ? 138 TYR A HE2  1 
ATOM   2163 H  HH   . TYR A 1 138 ? 39.71300  -12.25300 -24.38000 1.000 71.67000  ? 138 TYR A HH   1 
ATOM   2164 N  N    . ARG A 1 139 ? 36.78200  -18.61400 -25.19100 1.000 30.49839  ? 139 ARG A N    1 
ATOM   2165 C  CA   . ARG A 1 139 ? 38.02300  -19.27600 -25.56500 1.000 29.89306  ? 139 ARG A CA   1 
ATOM   2166 C  C    . ARG A 1 139 ? 37.92500  -19.86200 -26.96700 1.000 32.73550  ? 139 ARG A C    1 
ATOM   2167 O  O    . ARG A 1 139 ? 38.87700  -19.78800 -27.74800 1.000 33.08028  ? 139 ARG A O    1 
ATOM   2168 C  CB   . ARG A 1 139 ? 38.33400  -20.37800 -24.56200 1.000 33.39348  ? 139 ARG A CB   1 
ATOM   2169 C  CG   . ARG A 1 139 ? 38.91700  -19.86100 -23.27200 1.000 38.55725  ? 139 ARG A CG   1 
ATOM   2170 C  CD   . ARG A 1 139 ? 39.34900  -21.05700 -22.43600 1.000 41.12862  ? 139 ARG A CD   1 
ATOM   2171 N  NE   . ARG A 1 139 ? 40.72200  -21.33300 -22.84600 1.000 64.53405  ? 139 ARG A NE   1 
ATOM   2172 C  CZ   . ARG A 1 139 ? 41.46600  -22.34400 -22.42800 1.000 61.96532  ? 139 ARG A CZ   1 
ATOM   2173 N  NH1  . ARG A 1 139 ? 41.01100  -23.22400 -21.55200 1.000 53.68012  ? 139 ARG A NH1  1 
ATOM   2174 N  NH2  . ARG A 1 139 ? 42.69700  -22.48100 -22.91400 1.000 60.49673  ? 139 ARG A NH2  1 
ATOM   2175 H  H    . ARG A 1 139 ? 36.38400  -18.95300 -24.50800 1.000 36.60000  ? 139 ARG A H    1 
ATOM   2176 H  HA   . ARG A 1 139 ? 38.74600  -18.62900 -25.55100 1.000 35.87000  ? 139 ARG A HA   1 
ATOM   2177 H  HB2  . ARG A 1 139 ? 37.51400  -20.85100 -24.35100 1.000 40.07000  ? 139 ARG A HB2  1 
ATOM   2178 H  HB3  . ARG A 1 139 ? 38.97700  -20.98800 -24.95700 1.000 40.07000  ? 139 ARG A HB3  1 
ATOM   2179 H  HG2  . ARG A 1 139 ? 39.68900  -19.30300 -23.45400 1.000 46.27000  ? 139 ARG A HG2  1 
ATOM   2180 H  HG3  . ARG A 1 139 ? 38.25000  -19.35400 -22.78400 1.000 46.27000  ? 139 ARG A HG3  1 
ATOM   2181 H  HD2  . ARG A 1 139 ? 39.32200  -20.84400 -21.49000 1.000 49.35000  ? 139 ARG A HD2  1 
ATOM   2182 H  HD3  . ARG A 1 139 ? 38.78800  -21.82700 -22.61900 1.000 49.35000  ? 139 ARG A HD3  1 
ATOM   2183 H  HE   . ARG A 1 139 ? 41.07900  -20.79000 -23.40900 1.000 77.44000  ? 139 ARG A HE   1 
ATOM   2184 H  HH11 . ARG A 1 139 ? 40.21300  -23.14700 -21.24000 1.000 64.42000  ? 139 ARG A HH11 1 
ATOM   2185 H  HH12 . ARG A 1 139 ? 41.51200  -23.87400 -21.29400 1.000 64.42000  ? 139 ARG A HH12 1 
ATOM   2186 H  HH21 . ARG A 1 139 ? 42.99800  -21.91700 -23.48900 1.000 72.60000  ? 139 ARG A HH21 1 
ATOM   2187 H  HH22 . ARG A 1 139 ? 43.19300  -23.13300 -22.65200 1.000 72.60000  ? 139 ARG A HH22 1 
ATOM   2188 N  N    . ALA A 1 140 ? 36.78200  -20.47300 -27.28800 1.000 30.98003  ? 140 ALA A N    1 
ATOM   2189 C  CA   . ALA A 1 140 ? 36.61500  -21.10100 -28.59200 1.000 28.02178  ? 140 ALA A CA   1 
ATOM   2190 C  C    . ALA A 1 140 ? 36.69800  -20.07700 -29.71600 1.000 32.65128  ? 140 ALA A C    1 
ATOM   2191 O  O    . ALA A 1 140 ? 37.30300  -20.34500 -30.75700 1.000 31.95120  ? 140 ALA A O    1 
ATOM   2192 C  CB   . ALA A 1 140 ? 35.27500  -21.83100 -28.65500 1.000 28.26918  ? 140 ALA A CB   1 
ATOM   2193 H  H    . ALA A 1 140 ? 36.09700  -20.53700 -26.77200 1.000 37.18000  ? 140 ALA A H    1 
ATOM   2194 H  HA   . ALA A 1 140 ? 37.32700  -21.74800 -28.71400 1.000 33.63000  ? 140 ALA A HA   1 
ATOM   2195 H  HB1  . ALA A 1 140 ? 35.18100  -22.24400 -29.52700 1.000 33.92000  ? 140 ALA A HB1  1 
ATOM   2196 H  HB2  . ALA A 1 140 ? 35.25200  -22.51000 -27.96200 1.000 33.92000  ? 140 ALA A HB2  1 
ATOM   2197 H  HB3  . ALA A 1 140 ? 34.56000  -21.19100 -28.51300 1.000 33.92000  ? 140 ALA A HB3  1 
ATOM   2198 N  N    . ARG A 1 141 ? 36.08400  -18.90400 -29.53600 1.000 32.27229  ? 141 ARG A N    1 
ATOM   2199 C  CA   . ARG A 1 141 ? 36.20400  -17.86100 -30.55700 1.000 32.93290  ? 141 ARG A CA   1 
ATOM   2200 C  C    . ARG A 1 141 ? 37.66400  -17.45700 -30.75300 1.000 36.66755  ? 141 ARG A C    1 
ATOM   2201 O  O    . ARG A 1 141 ? 38.08900  -17.15200 -31.87600 1.000 38.94941  ? 141 ARG A O    1 
ATOM   2202 C  CB   . ARG A 1 141 ? 35.35000  -16.64200 -30.18500 1.000 35.45425  ? 141 ARG A CB   1 
ATOM   2203 C  CG   . ARG A 1 141 ? 33.87000  -16.97700 -30.01300 1.000 38.24406  ? 141 ARG A CG   1 
ATOM   2204 C  CD   . ARG A 1 141 ? 32.96200  -15.77300 -29.68500 1.000 40.36010  ? 141 ARG A CD   1 
ATOM   2205 N  NE   . ARG A 1 141 ? 33.32800  -14.53900 -30.36600 1.000 49.20064  ? 141 ARG A NE   1 
ATOM   2206 C  CZ   . ARG A 1 141 ? 33.84500  -13.47300 -29.77100 1.000 59.98088  ? 141 ARG A CZ   1 
ATOM   2207 N  NH1  . ARG A 1 141 ? 34.04500  -13.43900 -28.46100 1.000 52.46945  ? 141 ARG A NH1  1 
ATOM   2208 N  NH2  . ARG A 1 141 ? 34.15400  -12.40800 -30.50600 1.000 58.11749  ? 141 ARG A NH2  1 
ATOM   2209 H  H    . ARG A 1 141 ? 35.60700  -18.69200 -28.85300 1.000 38.73000  ? 141 ARG A H    1 
ATOM   2210 H  HA   . ARG A 1 141 ? 35.86700  -18.20700 -31.39900 1.000 39.52000  ? 141 ARG A HA   1 
ATOM   2211 H  HB2  . ARG A 1 141 ? 35.67200  -16.27700 -29.34600 1.000 42.55000  ? 141 ARG A HB2  1 
ATOM   2212 H  HB3  . ARG A 1 141 ? 35.42600  -15.97800 -30.88700 1.000 42.55000  ? 141 ARG A HB3  1 
ATOM   2213 H  HG2  . ARG A 1 141 ? 33.54500  -17.36800 -30.83900 1.000 45.89000  ? 141 ARG A HG2  1 
ATOM   2214 H  HG3  . ARG A 1 141 ? 33.78000  -17.61400 -29.28700 1.000 45.89000  ? 141 ARG A HG3  1 
ATOM   2215 H  HD2  . ARG A 1 141 ? 32.05300  -15.99100 -29.94400 1.000 48.43000  ? 141 ARG A HD2  1 
ATOM   2216 H  HD3  . ARG A 1 141 ? 33.00400  -15.60400 -28.73100 1.000 48.43000  ? 141 ARG A HD3  1 
ATOM   2217 H  HE   . ARG A 1 141 ? 33.20000  -14.49900 -31.21500 1.000 59.04000  ? 141 ARG A HE   1 
ATOM   2218 H  HH11 . ARG A 1 141 ? 33.83900  -14.11900 -27.97600 1.000 62.96000  ? 141 ARG A HH11 1 
ATOM   2219 H  HH12 . ARG A 1 141 ? 34.38200  -12.73700 -28.09600 1.000 62.96000  ? 141 ARG A HH12 1 
ATOM   2220 H  HH21 . ARG A 1 141 ? 34.01800  -12.41700 -31.35500 1.000 69.74000  ? 141 ARG A HH21 1 
ATOM   2221 H  HH22 . ARG A 1 141 ? 34.49000  -11.71000 -30.13200 1.000 69.74000  ? 141 ARG A HH22 1 
ATOM   2222 N  N    . ALA A 1 142 ? 38.44800  -17.45800 -29.67300 1.000 36.06748  ? 142 ALA A N    1 
ATOM   2223 C  CA   . ALA A 1 142 ? 39.86800  -17.15000 -29.76400 1.000 36.45963  ? 142 ALA A CA   1 
ATOM   2224 C  C    . ALA A 1 142 ? 40.67600  -18.26500 -30.41400 1.000 37.39396  ? 142 ALA A C    1 
ATOM   2225 O  O    . ALA A 1 142 ? 41.83100  -18.03300 -30.78000 1.000 43.29203  ? 142 ALA A O    1 
ATOM   2226 C  CB   . ALA A 1 142 ? 40.42400  -16.86000 -28.37000 1.000 36.78862  ? 142 ALA A CB   1 
ATOM   2227 H  H    . ALA A 1 142 ? 38.17800  -17.63300 -28.87600 1.000 43.28000  ? 142 ALA A H    1 
ATOM   2228 H  HA   . ALA A 1 142 ? 39.97800  -16.35300 -30.30600 1.000 43.75000  ? 142 ALA A HA   1 
ATOM   2229 H  HB1  . ALA A 1 142 ? 41.37300  -16.67300 -28.44200 1.000 44.14000  ? 142 ALA A HB1  1 
ATOM   2230 H  HB2  . ALA A 1 142 ? 39.96200  -16.09100 -28.00000 1.000 44.14000  ? 142 ALA A HB2  1 
ATOM   2231 H  HB3  . ALA A 1 142 ? 40.28100  -17.63500 -27.80600 1.000 44.14000  ? 142 ALA A HB3  1 
ATOM   2232 N  N    . GLY A 1 143 ? 40.11100  -19.45900 -30.55300 1.000 35.92273  ? 143 GLY A N    1 
ATOM   2233 C  CA   . GLY A 1 143 ? 40.79000  -20.57000 -31.18800 1.000 33.50139  ? 143 GLY A CA   1 
ATOM   2234 C  C    . GLY A 1 143 ? 40.99900  -21.78000 -30.31100 1.000 37.09655  ? 143 GLY A C    1 
ATOM   2235 O  O    . GLY A 1 143 ? 41.43400  -22.82400 -30.82000 1.000 36.75177  ? 143 GLY A O    1 
ATOM   2236 H  H    . GLY A 1 143 ? 39.31900  -19.64900 -30.28000 1.000 43.11000  ? 143 GLY A H    1 
ATOM   2237 H  HA2  . GLY A 1 143 ? 40.27100  -20.85000 -31.95800 1.000 40.20000  ? 143 GLY A HA2  1 
ATOM   2238 H  HA3  . GLY A 1 143 ? 41.66200  -20.26900 -31.48700 1.000 40.20000  ? 143 GLY A HA3  1 
ATOM   2239 N  N    . GLU A 1 144 ? 40.74200  -21.68800 -29.00700 1.000 35.45951  ? 144 GLU A N    1 
ATOM   2240 C  CA   . GLU A 1 144 ? 40.97700  -22.78800 -28.07400 1.000 35.66743  ? 144 GLU A CA   1 
ATOM   2241 C  C    . GLU A 1 144 ? 39.61600  -23.34900 -27.66800 1.000 33.16977  ? 144 GLU A C    1 
ATOM   2242 O  O    . GLU A 1 144 ? 39.08400  -23.04700 -26.60000 1.000 32.79604  ? 144 GLU A O    1 
ATOM   2243 C  CB   . GLU A 1 144 ? 41.79200  -22.28400 -26.87700 1.000 39.00731  ? 144 GLU A CB   1 
ATOM   2244 C  CG   . GLU A 1 144 ? 43.28600  -22.09500 -27.19900 1.000 47.67414  ? 144 GLU A CG   1 
ATOM   2245 C  CD   . GLU A 1 144 ? 43.58100  -20.75900 -27.87900 1.000 69.48728  ? 144 GLU A CD   1 
ATOM   2246 O  OE1  . GLU A 1 144 ? 42.95900  -19.74300 -27.51100 1.000 61.88637  ? 144 GLU A OE1  1 
ATOM   2247 O  OE2  . GLU A 1 144 ? 44.45100  -20.72600 -28.78900 1.000 79.91221  ? 144 GLU A OE2  1 
ATOM   2248 H  H    . GLU A 1 144 ? 40.42400  -20.98200 -28.63200 1.000 42.55000  ? 144 GLU A H    1 
ATOM   2249 H  HA   . GLU A 1 144 ? 41.47600  -23.50000 -28.50500 1.000 42.80000  ? 144 GLU A HA   1 
ATOM   2250 H  HB2  . GLU A 1 144 ? 41.43700  -21.42700 -26.59300 1.000 46.81000  ? 144 GLU A HB2  1 
ATOM   2251 H  HB3  . GLU A 1 144 ? 41.72100  -22.92700 -26.15500 1.000 46.81000  ? 144 GLU A HB3  1 
ATOM   2252 H  HG2  . GLU A 1 144 ? 43.79400  -22.13000 -26.37300 1.000 57.20000  ? 144 GLU A HG2  1 
ATOM   2253 H  HG3  . GLU A 1 144 ? 43.57200  -22.80500 -27.79500 1.000 57.20000  ? 144 GLU A HG3  1 
ATOM   2254 N  N    . ALA A 1 145 ? 39.06500  -24.21000 -28.52300 1.000 30.78264  ? 145 ALA A N    1 
ATOM   2255 C  CA   . ALA A 1 145 ? 37.68600  -24.65000 -28.39400 1.000 27.41908  ? 145 ALA A CA   1 
ATOM   2256 C  C    . ALA A 1 145 ? 37.52200  -26.00300 -27.72200 1.000 25.92153  ? 145 ALA A C    1 
ATOM   2257 O  O    . ALA A 1 145 ? 36.40500  -26.52500 -27.70500 1.000 27.44540  ? 145 ALA A O    1 
ATOM   2258 C  CB   . ALA A 1 145 ? 37.01200  -24.71200 -29.77000 1.000 29.76409  ? 145 ALA A CB   1 
ATOM   2259 H  H    A ALA A 1 145 ? 39.48000  -24.55600 -29.19200 0.550 36.94000  ? 145 ALA A H    1 
ATOM   2260 H  H    B ALA A 1 145 ? 39.48000  -24.55600 -29.19200 0.450 36.94000  ? 145 ALA A H    1 
ATOM   2261 H  HA   . ALA A 1 145 ? 37.23700  -23.98800 -27.84400 1.000 32.90000  ? 145 ALA A HA   1 
ATOM   2262 H  HB1  . ALA A 1 145 ? 36.08700  -24.98200 -29.65700 1.000 35.72000  ? 145 ALA A HB1  1 
ATOM   2263 H  HB2  . ALA A 1 145 ? 37.05300  -23.83500 -30.18200 1.000 35.72000  ? 145 ALA A HB2  1 
ATOM   2264 H  HB3  . ALA A 1 145 ? 37.48000  -25.35900 -30.32200 1.000 35.72000  ? 145 ALA A HB3  1 
ATOM   2265 N  N    . ALA A 1 146 ? 38.58900  -26.59200 -27.18200 1.000 30.02992  ? 146 ALA A N    1 
ATOM   2266 C  CA   . ALA A 1 146 ? 38.47100  -27.90900 -26.55400 1.000 30.15888  ? 146 ALA A CA   1 
ATOM   2267 C  C    . ALA A 1 146 ? 37.44500  -27.92300 -25.41700 1.000 27.19273  ? 146 ALA A C    1 
ATOM   2268 O  O    . ALA A 1 146 ? 36.59600  -28.81900 -25.34000 1.000 26.70057  ? 146 ALA A O    1 
ATOM   2269 C  CB   . ALA A 1 146 ? 39.83700  -28.37500 -26.03700 1.000 31.35113  ? 146 ALA A CB   1 
ATOM   2270 H  H    . ALA A 1 146 ? 39.38100  -26.25600 -27.16500 1.000 36.04000  ? 146 ALA A H    1 
ATOM   2271 H  HA   . ALA A 1 146 ? 38.16500  -28.53000 -27.23300 1.000 36.19000  ? 146 ALA A HA   1 
ATOM   2272 H  HB1  . ALA A 1 146 ? 39.73700  -29.24400 -25.61800 1.000 37.62000  ? 146 ALA A HB1  1 
ATOM   2273 H  HB2  . ALA A 1 146 ? 40.45300  -28.43600 -26.78300 1.000 37.62000  ? 146 ALA A HB2  1 
ATOM   2274 H  HB3  . ALA A 1 146 ? 40.16500  -27.73200 -25.38900 1.000 37.62000  ? 146 ALA A HB3  1 
ATOM   2275 N  N    . ASN A 1 147 ? 37.51200  -26.95500 -24.49900 1.000 29.89832  ? 147 ASN A N    1 
ATOM   2276 C  CA   . ASN A 1 147 ? 36.56100  -26.97700 -23.38300 1.000 28.71660  ? 147 ASN A CA   1 
ATOM   2277 C  C    . ASN A 1 147 ? 35.13500  -26.73000 -23.86600 1.000 28.01652  ? 147 ASN A C    1 
ATOM   2278 O  O    . ASN A 1 147 ? 34.20300  -27.39400 -23.42100 1.000 25.91890  ? 147 ASN A O    1 
ATOM   2279 C  CB   . ASN A 1 147 ? 36.99900  -25.96000 -22.33400 1.000 32.44073  ? 147 ASN A CB   1 
ATOM   2280 C  CG   . ASN A 1 147 ? 38.12400  -26.49300 -21.45200 1.000 31.96962  ? 147 ASN A CG   1 
ATOM   2281 O  OD1  . ASN A 1 147 ? 37.87200  -27.10200 -20.41300 1.000 44.92907  ? 147 ASN A OD1  1 
ATOM   2282 N  ND2  . ASN A 1 147 ? 39.34700  -26.32900 -21.88400 1.000 37.49660  ? 147 ASN A ND2  1 
ATOM   2283 H  H    . ASN A 1 147 ? 38.07200  -26.30300 -24.49900 1.000 35.88000  ? 147 ASN A H    1 
ATOM   2284 H  HA   . ASN A 1 147 ? 36.56300  -27.85100 -22.96200 1.000 34.46000  ? 147 ASN A HA   1 
ATOM   2285 H  HB2  . ASN A 1 147 ? 37.31700  -25.15900 -22.78000 1.000 38.93000  ? 147 ASN A HB2  1 
ATOM   2286 H  HB3  . ASN A 1 147 ? 36.24400  -25.74500 -21.76500 1.000 38.93000  ? 147 ASN A HB3  1 
ATOM   2287 H  HD21 . ASN A 1 147 ? 39.48900  -25.93400 -22.63500 1.000 45.00000  ? 147 ASN A HD21 1 
ATOM   2288 H  HD22 . ASN A 1 147 ? 40.01000  -26.61500 -21.41700 1.000 45.00000  ? 147 ASN A HD22 1 
ATOM   2289 N  N    . PHE A 1 148 ? 34.95500  -25.84100 -24.83800 1.000 27.84808  ? 148 PHE A N    1 
ATOM   2290 C  CA   . PHE A 1 148 ? 33.62200  -25.62300 -25.38200 1.000 27.21116  ? 148 PHE A CA   1 
ATOM   2291 C  C    . PHE A 1 148 ? 33.05300  -26.89800 -26.00700 1.000 26.97955  ? 148 PHE A C    1 
ATOM   2292 O  O    . PHE A 1 148 ? 31.89300  -27.26000 -25.76600 1.000 25.47148  ? 148 PHE A O    1 
ATOM   2293 C  CB   . PHE A 1 148 ? 33.66000  -24.48200 -26.40700 1.000 24.65032  ? 148 PHE A CB   1 
ATOM   2294 C  CG   . PHE A 1 148 ? 32.30000  -24.02300 -26.83900 1.000 25.87942  ? 148 PHE A CG   1 
ATOM   2295 C  CD1  . PHE A 1 148 ? 31.43600  -23.43700 -25.94100 1.000 27.90335  ? 148 PHE A CD1  1 
ATOM   2296 C  CD2  . PHE A 1 148 ? 31.89200  -24.15600 -28.16400 1.000 28.70344  ? 148 PHE A CD2  1 
ATOM   2297 C  CE1  . PHE A 1 148 ? 30.18500  -23.00900 -26.31900 1.000 27.89545  ? 148 PHE A CE1  1 
ATOM   2298 C  CE2  . PHE A 1 148 ? 30.64000  -23.73600 -28.54700 1.000 29.73778  ? 148 PHE A CE2  1 
ATOM   2299 C  CZ   . PHE A 1 148 ? 29.78500  -23.16400 -27.62500 1.000 30.20362  ? 148 PHE A CZ   1 
ATOM   2300 H  H    . PHE A 1 148 ? 35.57500  -25.36100 -25.19200 1.000 33.42000  ? 148 PHE A H    1 
ATOM   2301 H  HA   . PHE A 1 148 ? 33.03000  -25.36300 -24.65900 1.000 32.65000  ? 148 PHE A HA   1 
ATOM   2302 H  HB2  . PHE A 1 148 ? 34.11900  -23.72400 -26.01500 1.000 29.58000  ? 148 PHE A HB2  1 
ATOM   2303 H  HB3  . PHE A 1 148 ? 34.13500  -24.78600 -27.19600 1.000 29.58000  ? 148 PHE A HB3  1 
ATOM   2304 H  HD1  . PHE A 1 148 ? 31.70600  -23.32700 -25.05700 1.000 33.49000  ? 148 PHE A HD1  1 
ATOM   2305 H  HD2  . PHE A 1 148 ? 32.46800  -24.53000 -28.79200 1.000 34.45000  ? 148 PHE A HD2  1 
ATOM   2306 H  HE1  . PHE A 1 148 ? 29.61500  -22.61900 -25.69600 1.000 33.48000  ? 148 PHE A HE1  1 
ATOM   2307 H  HE2  . PHE A 1 148 ? 30.36800  -23.83700 -29.43100 1.000 35.69000  ? 148 PHE A HE2  1 
ATOM   2308 H  HZ   . PHE A 1 148 ? 28.93800  -22.88400 -27.88800 1.000 36.25000  ? 148 PHE A HZ   1 
ATOM   2309 N  N    . CYS A 1 149 ? 33.84900  -27.58600 -26.82800 1.000 27.08483  ? 149 CYS A N    1 
ATOM   2310 C  CA   . CYS A 1 149 ? 33.34200  -28.79100 -27.48400 1.000 27.11641  ? 149 CYS A CA   1 
ATOM   2311 C  C    . CYS A 1 149 ? 33.01300  -29.87800 -26.47400 1.000 28.31918  ? 149 CYS A C    1 
ATOM   2312 O  O    . CYS A 1 149 ? 31.99700  -30.56800 -26.60300 1.000 26.34263  ? 149 CYS A O    1 
ATOM   2313 C  CB   . CYS A 1 149 ? 34.36000  -29.30500 -28.49200 1.000 27.16115  ? 149 CYS A CB   1 
ATOM   2314 S  SG   . CYS A 1 149 ? 34.50300  -28.22400 -29.95300 1.000 28.16390  ? 149 CYS A SG   1 
ATOM   2315 H  H    . CYS A 1 149 ? 34.66300  -27.38200 -27.01800 1.000 32.50000  ? 149 CYS A H    1 
ATOM   2316 H  HA   . CYS A 1 149 ? 32.52700  -28.56100 -27.95800 1.000 32.54000  ? 149 CYS A HA   1 
ATOM   2317 H  HB2  . CYS A 1 149 ? 35.23000  -29.35400 -28.06600 1.000 32.59000  ? 149 CYS A HB2  1 
ATOM   2318 H  HB3  . CYS A 1 149 ? 34.08900  -30.18600 -28.79300 1.000 32.59000  ? 149 CYS A HB3  1 
ATOM   2319 H  HG   . CYS A 1 149 ? 35.30600  -28.69500 -30.71000 1.000 33.80000  ? 149 CYS A HG   1 
ATOM   2320 N  N    . ALA A 1 150 ? 33.86300  -30.04300 -25.46000 1.000 27.01640  ? 150 ALA A N    1 
ATOM   2321 C  CA   . ALA A 1 150 ? 33.58400  -31.01300 -24.40600 1.000 25.98206  ? 150 ALA A CA   1 
ATOM   2322 C  C    . ALA A 1 150 ? 32.30800  -30.66300 -23.64600 1.000 26.74268  ? 150 ALA A C    1 
ATOM   2323 O  O    . ALA A 1 150 ? 31.55100  -31.55500 -23.26200 1.000 27.11904  ? 150 ALA A O    1 
ATOM   2324 C  CB   . ALA A 1 150 ? 34.77300  -31.10300 -23.44200 1.000 26.66636  ? 150 ALA A CB   1 
ATOM   2325 H  H    . ALA A 1 150 ? 34.60000  -29.61000 -25.36000 1.000 32.42000  ? 150 ALA A H    1 
ATOM   2326 H  HA   . ALA A 1 150 ? 33.45800  -31.88400 -24.81500 1.000 31.18000  ? 150 ALA A HA   1 
ATOM   2327 H  HB1  . ALA A 1 150 ? 34.56200  -31.73400 -22.73700 1.000 32.00000  ? 150 ALA A HB1  1 
ATOM   2328 H  HB2  . ALA A 1 150 ? 35.55500  -31.40300 -23.93200 1.000 32.00000  ? 150 ALA A HB2  1 
ATOM   2329 H  HB3  . ALA A 1 150 ? 34.93900  -30.22500 -23.06200 1.000 32.00000  ? 150 ALA A HB3  1 
ATOM   2330 N  N    . LEU A 1 151 ? 32.05200  -29.37100 -23.41600 1.000 24.10552  ? 151 LEU A N    1 
ATOM   2331 C  CA   . LEU A 1 151 ? 30.79300  -28.97900 -22.79500 1.000 27.94282  ? 151 LEU A CA   1 
ATOM   2332 C  C    . LEU A 1 151 ? 29.60100  -29.25800 -23.70400 1.000 26.26631  ? 151 LEU A C    1 
ATOM   2333 O  O    . LEU A 1 151 ? 28.56800  -29.75000 -23.23200 1.000 28.70607  ? 151 LEU A O    1 
ATOM   2334 C  CB   . LEU A 1 151 ? 30.80700  -27.50100 -22.38700 1.000 28.35866  ? 151 LEU A CB   1 
ATOM   2335 C  CG   . LEU A 1 151 ? 31.68900  -27.11900 -21.22000 1.000 27.47961  ? 151 LEU A CG   1 
ATOM   2336 C  CD1  . LEU A 1 151 ? 31.77100  -25.60500 -21.03600 1.000 28.28760  ? 151 LEU A CD1  1 
ATOM   2337 C  CD2  . LEU A 1 151 ? 31.13400  -27.75400 -19.90500 1.000 27.45592  ? 151 LEU A CD2  1 
ATOM   2338 H  H    . LEU A 1 151 ? 32.58100  -28.72000 -23.60700 1.000 28.93000  ? 151 LEU A H    1 
ATOM   2339 H  HA   . LEU A 1 151 ? 30.69400  -29.50700 -21.98700 1.000 33.53000  ? 151 LEU A HA   1 
ATOM   2340 H  HB2  . LEU A 1 151 ? 31.10900  -26.98300 -23.15000 1.000 34.03000  ? 151 LEU A HB2  1 
ATOM   2341 H  HB3  . LEU A 1 151 ? 29.90100  -27.24700 -22.15200 1.000 34.03000  ? 151 LEU A HB3  1 
ATOM   2342 H  HG   . LEU A 1 151 ? 32.58200  -27.45100 -21.40200 1.000 32.97000  ? 151 LEU A HG   1 
ATOM   2343 H  HD11 . LEU A 1 151 ? 32.36200  -25.40900 -20.29200 1.000 33.94000  ? 151 LEU A HD11 1 
ATOM   2344 H  HD12 . LEU A 1 151 ? 32.11900  -25.20700 -21.84900 1.000 33.94000  ? 151 LEU A HD12 1 
ATOM   2345 H  HD13 . LEU A 1 151 ? 30.88300  -25.26100 -20.85200 1.000 33.94000  ? 151 LEU A HD13 1 
ATOM   2346 H  HD21 . LEU A 1 151 ? 31.65100  -27.42600 -19.15300 1.000 32.95000  ? 151 LEU A HD21 1 
ATOM   2347 H  HD22 . LEU A 1 151 ? 30.20300  -27.50300 -19.80100 1.000 32.95000  ? 151 LEU A HD22 1 
ATOM   2348 H  HD23 . LEU A 1 151 ? 31.21100  -28.71900 -19.96300 1.000 32.95000  ? 151 LEU A HD23 1 
ATOM   2349 N  N    . ILE A 1 152 ? 29.70300  -28.96100 -25.00800 1.000 26.79532  ? 152 ILE A N    1 
ATOM   2350 C  CA   . ILE A 1 152 ? 28.58000  -29.29000 -25.88000 1.000 27.41381  ? 152 ILE A CA   1 
ATOM   2351 C  C    . ILE A 1 152 ? 28.22700  -30.75600 -25.71300 1.000 23.72127  ? 152 ILE A C    1 
ATOM   2352 O  O    . ILE A 1 152 ? 27.05400  -31.13200 -25.58400 1.000 25.34778  ? 152 ILE A O    1 
ATOM   2353 C  CB   . ILE A 1 152 ? 28.89700  -28.98500 -27.35100 1.000 27.74543  ? 152 ILE A CB   1 
ATOM   2354 C  CG1  . ILE A 1 152 ? 29.14100  -27.50300 -27.58000 1.000 30.58261  ? 152 ILE A CG1  1 
ATOM   2355 C  CG2  . ILE A 1 152 ? 27.74100  -29.52200 -28.22200 1.000 29.47985  ? 152 ILE A CG2  1 
ATOM   2356 C  CD1  . ILE A 1 152 ? 29.48300  -27.17100 -29.01500 1.000 28.77977  ? 152 ILE A CD1  1 
ATOM   2357 H  H    . ILE A 1 152 ? 30.37900  -28.58800 -25.38800 1.000 32.15000  ? 152 ILE A H    1 
ATOM   2358 H  HA   . ILE A 1 152 ? 27.82800  -28.73600 -25.61900 1.000 32.89000  ? 152 ILE A HA   1 
ATOM   2359 H  HB   . ILE A 1 152 ? 29.72200  -29.43000 -27.60000 1.000 33.30000  ? 152 ILE A HB   1 
ATOM   2360 H  HG12 . ILE A 1 152 ? 28.33900  -27.01200 -27.34300 1.000 36.70000  ? 152 ILE A HG12 1 
ATOM   2361 H  HG13 . ILE A 1 152 ? 29.88200  -27.21600 -27.02300 1.000 36.70000  ? 152 ILE A HG13 1 
ATOM   2362 H  HG21 . ILE A 1 152 ? 27.78500  -29.10600 -29.09700 1.000 35.38000  ? 152 ILE A HG21 1 
ATOM   2363 H  HG22 . ILE A 1 152 ? 27.83200  -30.48400 -28.30900 1.000 35.38000  ? 152 ILE A HG22 1 
ATOM   2364 H  HG23 . ILE A 1 152 ? 26.89700  -29.30600 -27.79600 1.000 35.38000  ? 152 ILE A HG23 1 
ATOM   2365 H  HD11 . ILE A 1 152 ? 29.92800  -26.31000 -29.04300 1.000 34.54000  ? 152 ILE A HD11 1 
ATOM   2366 H  HD12 . ILE A 1 152 ? 30.07000  -27.85900 -29.36700 1.000 34.54000  ? 152 ILE A HD12 1 
ATOM   2367 H  HD13 . ILE A 1 152 ? 28.66400  -27.13800 -29.53500 1.000 34.54000  ? 152 ILE A HD13 1 
ATOM   2368 N  N    . LEU A 1 153 ? 29.25200  -31.60400 -25.77200 1.000 25.27935  ? 153 LEU A N    1 
ATOM   2369 C  CA   . LEU A 1 153 ? 29.05400  -33.04200 -25.66900 1.000 24.72928  ? 153 LEU A CA   1 
ATOM   2370 C  C    . LEU A 1 153 ? 28.37300  -33.38600 -24.35800 1.000 24.67664  ? 153 LEU A C    1 
ATOM   2371 O  O    . LEU A 1 153 ? 27.40300  -34.15200 -24.32500 1.000 27.06640  ? 153 LEU A O    1 
ATOM   2372 C  CB   . LEU A 1 153 ? 30.39500  -33.75000 -25.81500 1.000 24.86877  ? 153 LEU A CB   1 
ATOM   2373 C  CG   . LEU A 1 153 ? 30.93600  -33.70600 -27.25600 1.000 25.10301  ? 153 LEU A CG   1 
ATOM   2374 C  CD1  . LEU A 1 153 ? 32.40900  -33.97100 -27.25700 1.000 27.72438  ? 153 LEU A CD1  1 
ATOM   2375 C  CD2  . LEU A 1 153 ? 30.23200  -34.72200 -28.15400 1.000 25.76888  ? 153 LEU A CD2  1 
ATOM   2376 H  H    . LEU A 1 153 ? 30.07300  -31.37000 -25.87000 1.000 30.33000  ? 153 LEU A H    1 
ATOM   2377 H  HA   . LEU A 1 153 ? 28.48300  -33.35400 -26.38900 1.000 29.68000  ? 153 LEU A HA   1 
ATOM   2378 H  HB2  . LEU A 1 153 ? 31.04300  -33.31900 -25.23600 1.000 29.84000  ? 153 LEU A HB2  1 
ATOM   2379 H  HB3  . LEU A 1 153 ? 30.29000  -34.68000 -25.56000 1.000 29.84000  ? 153 LEU A HB3  1 
ATOM   2380 H  HG   . LEU A 1 153 ? 30.76500  -32.82200 -27.61800 1.000 30.12000  ? 153 LEU A HG   1 
ATOM   2381 H  HD11 . LEU A 1 153 ? 32.73700  -33.92800 -28.16900 1.000 33.27000  ? 153 LEU A HD11 1 
ATOM   2382 H  HD12 . LEU A 1 153 ? 32.85100  -33.30000 -26.71400 1.000 33.27000  ? 153 LEU A HD12 1 
ATOM   2383 H  HD13 . LEU A 1 153 ? 32.57100  -34.85400 -26.88900 1.000 33.27000  ? 153 LEU A HD13 1 
ATOM   2384 H  HD21 . LEU A 1 153 ? 30.64100  -34.70300 -29.03400 1.000 30.92000  ? 153 LEU A HD21 1 
ATOM   2385 H  HD22 . LEU A 1 153 ? 30.32600  -35.60600 -27.76500 1.000 30.92000  ? 153 LEU A HD22 1 
ATOM   2386 H  HD23 . LEU A 1 153 ? 29.29300  -34.48800 -28.22000 1.000 30.92000  ? 153 LEU A HD23 1 
ATOM   2387 N  N    . ALA A 1 154 ? 28.84800  -32.79900 -23.26200 1.000 26.17419  ? 154 ALA A N    1 
ATOM   2388 C  CA   . ALA A 1 154 ? 28.26600  -33.10200 -21.96300 1.000 24.70823  ? 154 ALA A CA   1 
ATOM   2389 C  C    . ALA A 1 154 ? 26.82500  -32.61500 -21.85900 1.000 23.87392  ? 154 ALA A C    1 
ATOM   2390 O  O    . ALA A 1 154 ? 25.94900  -33.34300 -21.37900 1.000 27.50330  ? 154 ALA A O    1 
ATOM   2391 C  CB   . ALA A 1 154 ? 29.11900  -32.47900 -20.85800 1.000 27.32433  ? 154 ALA A CB   1 
ATOM   2392 H  H    . ALA A 1 154 ? 29.49300  -32.23100 -23.24500 1.000 31.41000  ? 154 ALA A H    1 
ATOM   2393 H  HA   . ALA A 1 154 ? 28.26100  -34.06600 -21.84700 1.000 29.65000  ? 154 ALA A HA   1 
ATOM   2394 H  HB1  . ALA A 1 154 ? 28.72600  -32.69200 -19.99700 1.000 32.79000  ? 154 ALA A HB1  1 
ATOM   2395 H  HB2  . ALA A 1 154 ? 30.01700  -32.84100 -20.91000 1.000 32.79000  ? 154 ALA A HB2  1 
ATOM   2396 H  HB3  . ALA A 1 154 ? 29.14200  -31.51700 -20.98200 1.000 32.79000  ? 154 ALA A HB3  1 
ATOM   2397 N  N    . TYR A 1 155 ? 26.56400  -31.37700 -22.27600 1.000 24.99247  ? 155 TYR A N    1 
ATOM   2398 C  CA   . TYR A 1 155 ? 25.20600  -30.85800 -22.18500 1.000 25.28198  ? 155 TYR A CA   1 
ATOM   2399 C  C    . TYR A 1 155 ? 24.24800  -31.67700 -23.03900 1.000 28.89820  ? 155 TYR A C    1 
ATOM   2400 O  O    . TYR A 1 155 ? 23.10600  -31.93600 -22.63400 1.000 27.94019  ? 155 TYR A O    1 
ATOM   2401 C  CB   . TYR A 1 155 ? 25.17700  -29.39300 -22.60000 1.000 24.73454  ? 155 TYR A CB   1 
ATOM   2402 C  CG   . TYR A 1 155 ? 25.61200  -28.40200 -21.52900 1.000 24.17395  ? 155 TYR A CG   1 
ATOM   2403 C  CD1  . TYR A 1 155 ? 24.87100  -28.22800 -20.37000 1.000 27.73490  ? 155 TYR A CD1  1 
ATOM   2404 C  CD2  . TYR A 1 155 ? 26.76300  -27.66000 -21.68100 1.000 27.06904  ? 155 TYR A CD2  1 
ATOM   2405 C  CE1  . TYR A 1 155 ? 25.25900  -27.30600 -19.41300 1.000 26.66109  ? 155 TYR A CE1  1 
ATOM   2406 C  CE2  . TYR A 1 155 ? 27.17700  -26.75900 -20.71100 1.000 27.01113  ? 155 TYR A CE2  1 
ATOM   2407 C  CZ   . TYR A 1 155 ? 26.41500  -26.59500 -19.58300 1.000 26.63214  ? 155 TYR A CZ   1 
ATOM   2408 O  OH   . TYR A 1 155 ? 26.82200  -25.67500 -18.64600 1.000 27.67174  ? 155 TYR A OH   1 
ATOM   2409 H  H    . TYR A 1 155 ? 27.14100  -30.83200 -22.60600 1.000 29.99000  ? 155 TYR A H    1 
ATOM   2410 H  HA   . TYR A 1 155 ? 24.90900  -30.91400 -21.26300 1.000 30.34000  ? 155 TYR A HA   1 
ATOM   2411 H  HB2  . TYR A 1 155 ? 25.77000  -29.27900 -23.35800 1.000 29.68000  ? 155 TYR A HB2  1 
ATOM   2412 H  HB3  . TYR A 1 155 ? 24.26800  -29.16500 -22.85200 1.000 29.68000  ? 155 TYR A HB3  1 
ATOM   2413 H  HD1  . TYR A 1 155 ? 24.10400  -28.73600 -20.23500 1.000 33.28000  ? 155 TYR A HD1  1 
ATOM   2414 H  HD2  . TYR A 1 155 ? 27.27400  -27.76600 -22.45100 1.000 32.48000  ? 155 TYR A HD2  1 
ATOM   2415 H  HE1  . TYR A 1 155 ? 24.73500  -27.17100 -18.65600 1.000 31.99000  ? 155 TYR A HE1  1 
ATOM   2416 H  HE2  . TYR A 1 155 ? 27.96100  -26.27200 -20.82400 1.000 32.41000  ? 155 TYR A HE2  1 
ATOM   2417 H  HH   . TYR A 1 155 ? 26.21600  -25.55800 -18.07600 1.000 33.21000  ? 155 TYR A HH   1 
ATOM   2418 N  N    . CYS A 1 156 ? 24.70100  -32.11500 -24.21200 1.000 26.99271  ? 156 CYS A N    1 
ATOM   2419 C  CA   . CYS A 1 156 ? 23.85500  -32.87000 -25.12800 1.000 29.63513  ? 156 CYS A CA   1 
ATOM   2420 C  C    . CYS A 1 156 ? 23.82600  -34.36500 -24.85400 1.000 29.26930  ? 156 CYS A C    1 
ATOM   2421 O  O    . CYS A 1 156 ? 23.12300  -35.09100 -25.57700 1.000 29.57986  ? 156 CYS A O    1 
ATOM   2422 C  CB   . CYS A 1 156 ? 24.30100  -32.65400 -26.57500 1.000 27.91651  ? 156 CYS A CB   1 
ATOM   2423 S  SG   . CYS A 1 156 ? 24.12500  -30.96300 -27.13600 1.000 30.22731  ? 156 CYS A SG   1 
ATOM   2424 H  H    . CYS A 1 156 ? 25.50100  -31.98600 -24.50000 1.000 32.39000  ? 156 CYS A H    1 
ATOM   2425 H  HA   . CYS A 1 156 ? 22.95300  -32.52900 -25.02500 1.000 35.56000  ? 156 CYS A HA   1 
ATOM   2426 H  HB2  . CYS A 1 156 ? 25.23800  -32.89600 -26.65300 1.000 33.50000  ? 156 CYS A HB2  1 
ATOM   2427 H  HB3  . CYS A 1 156 ? 23.76400  -33.21700 -27.15500 1.000 33.50000  ? 156 CYS A HB3  1 
ATOM   2428 H  HG   . CYS A 1 156 ? 24.58400  -30.86800 -28.24100 1.000 36.27000  ? 156 CYS A HG   1 
ATOM   2429 N  N    . ASN A 1 157 ? 24.54000  -34.85000 -23.83100 1.000 27.69016  ? 157 ASN A N    1 
ATOM   2430 C  CA   . ASN A 1 157 ? 24.54700  -36.27400 -23.50900 1.000 28.03231  ? 157 ASN A CA   1 
ATOM   2431 C  C    . ASN A 1 157 ? 25.01600  -37.09500 -24.70600 1.000 31.00898  ? 157 ASN A C    1 
ATOM   2432 O  O    . ASN A 1 157 ? 24.44700  -38.13300 -25.04900 1.000 30.48260  ? 157 ASN A O    1 
ATOM   2433 C  CB   . ASN A 1 157 ? 23.17000  -36.72200 -23.03700 1.000 30.19046  ? 157 ASN A CB   1 
ATOM   2434 C  CG   . ASN A 1 157 ? 22.95100  -36.40000 -21.59900 1.000 38.96783  ? 157 ASN A CG   1 
ATOM   2435 O  OD1  . ASN A 1 157 ? 22.41700  -35.34000 -21.27300 1.000 39.82846  ? 157 ASN A OD1  1 
ATOM   2436 N  ND2  . ASN A 1 157 ? 23.38000  -37.29300 -20.72000 1.000 36.60965  ? 157 ASN A ND2  1 
ATOM   2437 H  H    . ASN A 1 157 ? 25.02700  -34.37000 -23.31000 1.000 33.23000  ? 157 ASN A H    1 
ATOM   2438 H  HA   . ASN A 1 157 ? 25.17500  -36.43500 -22.78700 1.000 33.64000  ? 157 ASN A HA   1 
ATOM   2439 H  HB2  . ASN A 1 157 ? 22.49000  -36.26800 -23.55800 1.000 36.23000  ? 157 ASN A HB2  1 
ATOM   2440 H  HB3  . ASN A 1 157 ? 23.08900  -37.68200 -23.15000 1.000 36.23000  ? 157 ASN A HB3  1 
ATOM   2441 H  HD21 . ASN A 1 157 ? 23.76300  -38.01400 -20.99200 1.000 43.93000  ? 157 ASN A HD21 1 
ATOM   2442 H  HD22 . ASN A 1 157 ? 23.27700  -37.15200 -19.87800 1.000 43.93000  ? 157 ASN A HD22 1 
ATOM   2443 N  N    . LYS A 1 158 ? 26.07300  -36.61500 -25.34800 1.000 28.81924  ? 158 LYS A N    1 
ATOM   2444 C  CA   . LYS A 1 158 ? 26.73900  -37.29900 -26.43600 1.000 30.18520  ? 158 LYS A CA   1 
ATOM   2445 C  C    . LYS A 1 158 ? 28.17500  -37.58900 -26.02200 1.000 27.77701  ? 158 LYS A C    1 
ATOM   2446 O  O    . LYS A 1 158 ? 28.85400  -36.72900 -25.45800 1.000 29.81673  ? 158 LYS A O    1 
ATOM   2447 C  CB   . LYS A 1 158 ? 26.73000  -36.41700 -27.69800 1.000 28.58764  ? 158 LYS A CB   1 
ATOM   2448 C  CG   . LYS A 1 158 ? 25.37300  -36.21700 -28.30500 1.000 30.05624  ? 158 LYS A CG   1 
ATOM   2449 C  CD   . LYS A 1 158 ? 24.79200  -37.52200 -28.79200 1.000 30.19836  ? 158 LYS A CD   1 
ATOM   2450 C  CE   . LYS A 1 158 ? 23.45700  -37.27700 -29.46300 1.000 37.68610  ? 158 LYS A CE   1 
ATOM   2451 N  NZ   . LYS A 1 158 ? 22.43000  -36.92500 -28.43700 1.000 43.95264  ? 158 LYS A NZ   1 
ATOM   2452 H  H    . LYS A 1 158 ? 26.43600  -35.85800 -25.16000 1.000 34.58000  ? 158 LYS A H    1 
ATOM   2453 H  HA   . LYS A 1 158 ? 26.29700  -38.13900 -26.63800 1.000 36.22000  ? 158 LYS A HA   1 
ATOM   2454 H  HB2  . LYS A 1 158 ? 27.08000  -35.54300 -27.46700 1.000 34.31000  ? 158 LYS A HB2  1 
ATOM   2455 H  HB3  . LYS A 1 158 ? 27.29200  -36.83300 -28.37000 1.000 34.31000  ? 158 LYS A HB3  1 
ATOM   2456 H  HG2  . LYS A 1 158 ? 24.77400  -35.84500 -27.63800 1.000 36.07000  ? 158 LYS A HG2  1 
ATOM   2457 H  HG3  . LYS A 1 158 ? 25.44400  -35.61300 -29.06000 1.000 36.07000  ? 158 LYS A HG3  1 
ATOM   2458 H  HD2  . LYS A 1 158 ? 25.39400  -37.92800 -29.43500 1.000 36.24000  ? 158 LYS A HD2  1 
ATOM   2459 H  HD3  . LYS A 1 158 ? 24.65600  -38.12000 -28.04000 1.000 36.24000  ? 158 LYS A HD3  1 
ATOM   2460 H  HE2  . LYS A 1 158 ? 23.53700  -36.54100 -30.09000 1.000 45.23000  ? 158 LYS A HE2  1 
ATOM   2461 H  HE3  . LYS A 1 158 ? 23.17200  -38.07900 -29.92800 1.000 45.23000  ? 158 LYS A HE3  1 
ATOM   2462 H  HZ1  . LYS A 1 158 ? 21.64500  -36.78100 -28.83000 1.000 52.74000  ? 158 LYS A HZ1  1 
ATOM   2463 H  HZ2  . LYS A 1 158 ? 22.34300  -37.59100 -27.85300 1.000 52.74000  ? 158 LYS A HZ2  1 
ATOM   2464 H  HZ3  . LYS A 1 158 ? 22.67500  -36.18900 -28.00100 1.000 52.74000  ? 158 LYS A HZ3  1 
ATOM   2465 N  N    . THR A 1 159 ? 28.63600  -38.80200 -26.28600 1.000 28.53500  ? 159 THR A N    1 
ATOM   2466 C  CA   . THR A 1 159 ? 30.04100  -39.10800 -26.06800 1.000 29.85884  ? 159 THR A CA   1 
ATOM   2467 C  C    . THR A 1 159 ? 30.83600  -38.80500 -27.33100 1.000 29.92990  ? 159 THR A C    1 
ATOM   2468 O  O    . THR A 1 159 ? 30.28800  -38.71300 -28.43400 1.000 28.32971  ? 159 THR A O    1 
ATOM   2469 C  CB   . THR A 1 159 ? 30.28200  -40.56500 -25.68000 1.000 29.83779  ? 159 THR A CB   1 
ATOM   2470 O  OG1  . THR A 1 159 ? 29.70300  -41.43500 -26.64500 1.000 35.13053  ? 159 THR A OG1  1 
ATOM   2471 C  CG2  . THR A 1 159 ? 29.70800  -40.85700 -24.30100 1.000 36.60702  ? 159 THR A CG2  1 
ATOM   2472 H  H    . THR A 1 159 ? 28.16300  -39.45400 -26.58600 1.000 34.24000  ? 159 THR A H    1 
ATOM   2473 H  HA   . THR A 1 159 ? 30.35100  -38.56000 -25.33000 1.000 35.83000  ? 159 THR A HA   1 
ATOM   2474 H  HB   . THR A 1 159 ? 31.23700  -40.73300 -25.64700 1.000 35.80000  ? 159 THR A HB   1 
ATOM   2475 H  HG1  . THR A 1 159 ? 29.86400  -42.23500 -26.44300 1.000 42.16000  ? 159 THR A HG1  1 
ATOM   2476 H  HG21 . THR A 1 159 ? 29.87600  -41.78100 -24.06000 1.000 43.93000  ? 159 THR A HG21 1 
ATOM   2477 H  HG22 . THR A 1 159 ? 30.12200  -40.27900 -23.64100 1.000 43.93000  ? 159 THR A HG22 1 
ATOM   2478 H  HG23 . THR A 1 159 ? 28.75100  -40.70000 -24.30100 1.000 43.93000  ? 159 THR A HG23 1 
ATOM   2479 N  N    . VAL A 1 160 ? 32.14700  -38.65300 -27.15700 1.000 30.00097  ? 160 VAL A N    1 
ATOM   2480 C  CA   . VAL A 1 160 ? 33.02900  -38.51900 -28.31100 1.000 28.16127  ? 160 VAL A CA   1 
ATOM   2481 C  C    . VAL A 1 160 ? 32.87800  -39.73900 -29.19900 1.000 30.05360  ? 160 VAL A C    1 
ATOM   2482 O  O    . VAL A 1 160 ? 32.93900  -40.88500 -28.73200 1.000 30.90107  ? 160 VAL A O    1 
ATOM   2483 C  CB   . VAL A 1 160 ? 34.47800  -38.34600 -27.83800 1.000 28.75608  ? 160 VAL A CB   1 
ATOM   2484 C  CG1  . VAL A 1 160 ? 35.43900  -38.45000 -29.00100 1.000 31.50641  ? 160 VAL A CG1  1 
ATOM   2485 C  CG2  . VAL A 1 160 ? 34.62800  -37.01500 -27.12400 1.000 31.39324  ? 160 VAL A CG2  1 
ATOM   2486 H  H    . VAL A 1 160 ? 32.54400  -38.62500 -26.39400 1.000 36.00000  ? 160 VAL A H    1 
ATOM   2487 H  HA   . VAL A 1 160 ? 32.77500  -37.73600 -28.82400 1.000 33.80000  ? 160 VAL A HA   1 
ATOM   2488 H  HB   . VAL A 1 160 ? 34.70000  -39.05600 -27.21600 1.000 34.51000  ? 160 VAL A HB   1 
ATOM   2489 H  HG11 . VAL A 1 160 ? 36.29800  -38.08700 -28.73500 1.000 37.81000  ? 160 VAL A HG11 1 
ATOM   2490 H  HG12 . VAL A 1 160 ? 35.53600  -39.38300 -29.24800 1.000 37.81000  ? 160 VAL A HG12 1 
ATOM   2491 H  HG13 . VAL A 1 160 ? 35.08400  -37.94600 -29.75000 1.000 37.81000  ? 160 VAL A HG13 1 
ATOM   2492 H  HG21 . VAL A 1 160 ? 35.48200  -36.99800 -26.66400 1.000 37.67000  ? 160 VAL A HG21 1 
ATOM   2493 H  HG22 . VAL A 1 160 ? 34.59000  -36.30000 -27.77800 1.000 37.67000  ? 160 VAL A HG22 1 
ATOM   2494 H  HG23 . VAL A 1 160 ? 33.90500  -36.91700 -26.48400 1.000 37.67000  ? 160 VAL A HG23 1 
ATOM   2495 N  N    . GLY A 1 161 ? 32.72100  -39.50300 -30.49900 1.000 30.18257  ? 161 GLY A N    1 
ATOM   2496 C  CA   . GLY A 1 161 ? 32.47600  -40.57000 -31.42500 1.000 30.95371  ? 161 GLY A CA   1 
ATOM   2497 C  C    . GLY A 1 161 ? 31.01900  -40.82100 -31.73300 1.000 31.61958  ? 161 GLY A C    1 
ATOM   2498 O  O    . GLY A 1 161 ? 30.71200  -41.40400 -32.77400 1.000 30.91423  ? 161 GLY A O    1 
ATOM   2499 H  H    . GLY A 1 161 ? 32.75400  -38.72300 -30.85800 1.000 36.22000  ? 161 GLY A H    1 
ATOM   2500 H  HA2  . GLY A 1 161 ? 32.92400  -40.36500 -32.26000 1.000 37.14000  ? 161 GLY A HA2  1 
ATOM   2501 H  HA3  . GLY A 1 161 ? 32.84600  -41.38900 -31.06000 1.000 37.14000  ? 161 GLY A HA3  1 
ATOM   2502 N  N    . GLU A 1 162 ? 30.11100  -40.39400 -30.86800 1.000 29.60618  ? 162 GLU A N    1 
ATOM   2503 C  CA   . GLU A 1 162 ? 28.68800  -40.64700 -31.07500 1.000 29.35615  ? 162 GLU A CA   1 
ATOM   2504 C  C    . GLU A 1 162 ? 28.13100  -39.72700 -32.15600 1.000 27.95072  ? 162 GLU A C    1 
ATOM   2505 O  O    . GLU A 1 162 ? 28.48100  -38.54200 -32.23000 1.000 29.55091  ? 162 GLU A O    1 
ATOM   2506 C  CB   . GLU A 1 162 ? 27.94500  -40.45900 -29.74800 1.000 32.59601  ? 162 GLU A CB   1 
ATOM   2507 C  CG   . GLU A 1 162 ? 26.51900  -40.95200 -29.75400 1.000 36.84389  ? 162 GLU A CG   1 
ATOM   2508 C  CD   . GLU A 1 162 ? 25.87100  -40.96800 -28.37200 1.000 37.42817  ? 162 GLU A CD   1 
ATOM   2509 O  OE1  . GLU A 1 162 ? 26.53500  -40.60300 -27.36400 1.000 38.18353  ? 162 GLU A OE1  1 
ATOM   2510 O  OE2  . GLU A 1 162 ? 24.67500  -41.32800 -28.32400 1.000 33.39611  ? 162 GLU A OE2  1 
ATOM   2511 H  H    . GLU A 1 162 ? 30.29100  -39.95500 -30.15000 1.000 35.53000  ? 162 GLU A H    1 
ATOM   2512 H  HA   . GLU A 1 162 ? 28.54400  -41.55700 -31.37800 1.000 35.23000  ? 162 GLU A HA   1 
ATOM   2513 H  HB2  . GLU A 1 162 ? 28.42000  -40.94600 -29.05600 1.000 39.11000  ? 162 GLU A HB2  1 
ATOM   2514 H  HB3  . GLU A 1 162 ? 27.92700  -39.51300 -29.53500 1.000 39.11000  ? 162 GLU A HB3  1 
ATOM   2515 H  HG2  . GLU A 1 162 ? 25.99000  -40.37100 -30.32300 1.000 44.21000  ? 162 GLU A HG2  1 
ATOM   2516 H  HG3  . GLU A 1 162 ? 26.50300  -41.85800 -30.10000 1.000 44.21000  ? 162 GLU A HG3  1 
ATOM   2517 N  N    . LEU A 1 163 ? 27.25800  -40.27200 -33.00000 1.000 30.38785  ? 163 LEU A N    1 
ATOM   2518 C  CA   . LEU A 1 163 ? 26.63200  -39.43300 -34.00600 1.000 31.66169  ? 163 LEU A CA   1 
ATOM   2519 C  C    . LEU A 1 163 ? 25.68300  -38.43400 -33.35200 1.000 29.37721  ? 163 LEU A C    1 
ATOM   2520 O  O    . LEU A 1 163 ? 25.07700  -38.70700 -32.29600 1.000 30.96161  ? 163 LEU A O    1 
ATOM   2521 C  CB   . LEU A 1 163 ? 25.89200  -40.27700 -35.04000 1.000 31.37481  ? 163 LEU A CB   1 
ATOM   2522 C  CG   . LEU A 1 163 ? 26.79700  -41.25100 -35.80000 1.000 34.64100  ? 163 LEU A CG   1 
ATOM   2523 C  CD1  . LEU A 1 163 ? 26.01100  -41.97600 -36.90100 1.000 34.09619  ? 163 LEU A CD1  1 
ATOM   2524 C  CD2  . LEU A 1 163 ? 28.02500  -40.55100 -36.39100 1.000 36.85179  ? 163 LEU A CD2  1 
ATOM   2525 H  H    . LEU A 1 163 ? 27.02200  -41.09900 -33.00700 1.000 36.46000  ? 163 LEU A H    1 
ATOM   2526 H  HA   . LEU A 1 163 ? 27.31600  -38.93500 -34.48000 1.000 37.99000  ? 163 LEU A HA   1 
ATOM   2527 H  HB2  . LEU A 1 163 ? 25.21000  -40.79700 -34.58800 1.000 37.65000  ? 163 LEU A HB2  1 
ATOM   2528 H  HB3  . LEU A 1 163 ? 25.48200  -39.68500 -35.69000 1.000 37.65000  ? 163 LEU A HB3  1 
ATOM   2529 H  HG   . LEU A 1 163 ? 27.12100  -41.91100 -35.16600 1.000 41.57000  ? 163 LEU A HG   1 
ATOM   2530 H  HD11 . LEU A 1 163 ? 26.61300  -42.56300 -37.38500 1.000 40.91000  ? 163 LEU A HD11 1 
ATOM   2531 H  HD12 . LEU A 1 163 ? 25.30100  -42.49600 -36.49300 1.000 40.91000  ? 163 LEU A HD12 1 
ATOM   2532 H  HD13 . LEU A 1 163 ? 25.63300  -41.31800 -37.50500 1.000 40.91000  ? 163 LEU A HD13 1 
ATOM   2533 H  HD21 . LEU A 1 163 ? 28.47200  -41.16000 -37.00000 1.000 44.22000  ? 163 LEU A HD21 1 
ATOM   2534 H  HD22 . LEU A 1 163 ? 27.73600  -39.75800 -36.87000 1.000 44.22000  ? 163 LEU A HD22 1 
ATOM   2535 H  HD23 . LEU A 1 163 ? 28.62500  -40.30300 -35.67100 1.000 44.22000  ? 163 LEU A HD23 1 
ATOM   2536 N  N    . GLY A 1 164 ? 25.62100  -37.24000 -33.95400 1.000 27.99020  ? 164 GLY A N    1 
ATOM   2537 C  CA   . GLY A 1 164 ? 24.75200  -36.18800 -33.48600 1.000 27.17957  ? 164 GLY A CA   1 
ATOM   2538 C  C    . GLY A 1 164 ? 24.05100  -35.47400 -34.63200 1.000 28.27444  ? 164 GLY A C    1 
ATOM   2539 O  O    . GLY A 1 164 ? 24.52600  -35.43400 -35.77900 1.000 28.75871  ? 164 GLY A O    1 
ATOM   2540 H  H    . GLY A 1 164 ? 26.08400  -37.02300 -34.64500 1.000 33.59000  ? 164 GLY A H    1 
ATOM   2541 H  HA2  . GLY A 1 164 ? 24.07700  -36.56400 -32.89900 1.000 32.62000  ? 164 GLY A HA2  1 
ATOM   2542 H  HA3  . GLY A 1 164 ? 25.27300  -35.53600 -32.99100 1.000 32.62000  ? 164 GLY A HA3  1 
ATOM   2543 N  N    . ASP A 1 165 ? 22.90700  -34.88100 -34.29100 1.000 25.42410  ? 165 ASP A N    1 
ATOM   2544 C  CA   . ASP A 1 165 ? 22.08300  -34.09800 -35.21800 1.000 24.65032  ? 165 ASP A CA   1 
ATOM   2545 C  C    . ASP A 1 165 ? 22.30200  -32.61800 -34.91000 1.000 26.68478  ? 165 ASP A C    1 
ATOM   2546 O  O    . ASP A 1 165 ? 22.26300  -32.20100 -33.75000 1.000 25.42147  ? 165 ASP A O    1 
ATOM   2547 C  CB   . ASP A 1 165 ? 20.61600  -34.51200 -35.06300 1.000 25.17144  ? 165 ASP A CB   1 
ATOM   2548 C  CG   . ASP A 1 165 ? 19.66900  -33.72800 -35.89600 1.000 30.23520  ? 165 ASP A CG   1 
ATOM   2549 O  OD1  . ASP A 1 165 ? 19.46400  -34.10000 -37.06500 1.000 28.94294  ? 165 ASP A OD1  1 
ATOM   2550 O  OD2  . ASP A 1 165 ? 19.09700  -32.75200 -35.38800 1.000 28.10337  ? 165 ASP A OD2  1 
ATOM   2551 H  H    . ASP A 1 165 ? 22.57300  -34.91700 -33.49900 1.000 30.51000  ? 165 ASP A H    1 
ATOM   2552 H  HA   . ASP A 1 165 ? 22.33100  -34.24400 -36.14400 1.000 29.58000  ? 165 ASP A HA   1 
ATOM   2553 H  HB2  . ASP A 1 165 ? 20.52900  -35.44400 -35.31700 1.000 30.21000  ? 165 ASP A HB2  1 
ATOM   2554 H  HB3  . ASP A 1 165 ? 20.35800  -34.39600 -34.13600 1.000 30.21000  ? 165 ASP A HB3  1 
ATOM   2555 N  N    . VAL A 1 166 ? 22.55300  -31.82600 -35.94700 1.000 26.91639  ? 166 VAL A N    1 
ATOM   2556 C  CA   . VAL A 1 166 ? 22.84600  -30.41000 -35.73200 1.000 24.70823  ? 166 VAL A CA   1 
ATOM   2557 C  C    . VAL A 1 166 ? 21.64300  -29.68700 -35.13800 1.000 27.12167  ? 166 VAL A C    1 
ATOM   2558 O  O    . VAL A 1 166 ? 21.78300  -28.88500 -34.20200 1.000 28.54290  ? 166 VAL A O    1 
ATOM   2559 C  CB   . VAL A 1 166 ? 23.30700  -29.75700 -37.05300 1.000 24.66085  ? 166 VAL A CB   1 
ATOM   2560 C  CG1  . VAL A 1 166 ? 23.27300  -28.25800 -36.93300 1.000 27.24800  ? 166 VAL A CG1  1 
ATOM   2561 C  CG2  . VAL A 1 166 ? 24.70700  -30.21900 -37.37800 1.000 25.73993  ? 166 VAL A CG2  1 
ATOM   2562 H  H    . VAL A 1 166 ? 22.56000  -32.07600 -36.76900 1.000 32.30000  ? 166 VAL A H    1 
ATOM   2563 H  HA   . VAL A 1 166 ? 23.57100  -30.34300 -35.09000 1.000 29.65000  ? 166 VAL A HA   1 
ATOM   2564 H  HB   . VAL A 1 166 ? 22.71000  -30.02000 -37.77100 1.000 29.60000  ? 166 VAL A HB   1 
ATOM   2565 H  HG11 . VAL A 1 166 ? 23.80800  -27.87200 -37.64400 1.000 32.70000  ? 166 VAL A HG11 1 
ATOM   2566 H  HG12 . VAL A 1 166 ? 22.35400  -27.95600 -37.00900 1.000 32.70000  ? 166 VAL A HG12 1 
ATOM   2567 H  HG13 . VAL A 1 166 ? 23.63500  -28.00200 -36.07100 1.000 32.70000  ? 166 VAL A HG13 1 
ATOM   2568 H  HG21 . VAL A 1 166 ? 24.89200  -30.03100 -38.31100 1.000 30.89000  ? 166 VAL A HG21 1 
ATOM   2569 H  HG22 . VAL A 1 166 ? 25.33500  -29.74200 -36.81300 1.000 30.89000  ? 166 VAL A HG22 1 
ATOM   2570 H  HG23 . VAL A 1 166 ? 24.77100  -31.17200 -37.21300 1.000 30.89000  ? 166 VAL A HG23 1 
ATOM   2571 N  N    . ARG A 1 167 ? 20.44200  -29.96400 -35.65800 1.000 23.28437  ? 167 ARG A N    1 
ATOM   2572 C  CA   . ARG A 1 167 ? 19.25000  -29.25500 -35.19000 1.000 24.79771  ? 167 ARG A CA   1 
ATOM   2573 C  C    . ARG A 1 167 ? 19.04400  -29.51400 -33.70600 1.000 25.61623  ? 167 ARG A C    1 
ATOM   2574 O  O    . ARG A 1 167 ? 18.76900  -28.59100 -32.93400 1.000 29.25088  ? 167 ARG A O    1 
ATOM   2575 C  CB   . ARG A 1 167 ? 18.00600  -29.67100 -35.97400 1.000 28.21391  ? 167 ARG A CB   1 
ATOM   2576 C  CG   . ARG A 1 167 ? 16.74700  -28.82900 -35.66600 1.000 28.76924  ? 167 ARG A CG   1 
ATOM   2577 C  CD   . ARG A 1 167 ? 15.46300  -29.65600 -35.62800 1.000 29.41405  ? 167 ARG A CD   1 
ATOM   2578 N  NE   . ARG A 1 167 ? 15.36900  -30.38300 -34.37300 1.000 34.72785  ? 167 ARG A NE   1 
ATOM   2579 C  CZ   . ARG A 1 167 ? 14.89400  -29.89000 -33.24100 1.000 33.25925  ? 167 ARG A CZ   1 
ATOM   2580 N  NH1  . ARG A 1 167 ? 14.26600  -28.72800 -33.20100 1.000 31.85645  ? 167 ARG A NH1  1 
ATOM   2581 N  NH2  . ARG A 1 167 ? 15.05300  -30.58100 -32.11800 1.000 34.39886  ? 167 ARG A NH2  1 
ATOM   2582 H  H    . ARG A 1 167 ? 20.29400  -30.54800 -36.27200 1.000 27.94000  ? 167 ARG A H    1 
ATOM   2583 H  HA   . ARG A 1 167 ? 19.37500  -28.30500 -35.34400 1.000 29.76000  ? 167 ARG A HA   1 
ATOM   2584 H  HB2  . ARG A 1 167 ? 18.19400  -29.58300 -36.92100 1.000 33.86000  ? 167 ARG A HB2  1 
ATOM   2585 H  HB3  . ARG A 1 167 ? 17.80100  -30.59500 -35.76000 1.000 33.86000  ? 167 ARG A HB3  1 
ATOM   2586 H  HG2  . ARG A 1 167 ? 16.85500  -28.40700 -34.80000 1.000 34.52000  ? 167 ARG A HG2  1 
ATOM   2587 H  HG3  . ARG A 1 167 ? 16.64500  -28.15300 -36.35400 1.000 34.52000  ? 167 ARG A HG3  1 
ATOM   2588 H  HD2  . ARG A 1 167 ? 14.69500  -29.06800 -35.70400 1.000 35.30000  ? 167 ARG A HD2  1 
ATOM   2589 H  HD3  . ARG A 1 167 ? 15.46500  -30.29500 -36.35700 1.000 35.30000  ? 167 ARG A HD3  1 
ATOM   2590 H  HE   . ARG A 1 167 ? 15.64400  -31.19800 -34.36500 1.000 41.67000  ? 167 ARG A HE   1 
ATOM   2591 H  HH11 . ARG A 1 167 ? 14.15800  -28.27200 -33.92300 1.000 38.23000  ? 167 ARG A HH11 1 
ATOM   2592 H  HH12 . ARG A 1 167 ? 13.96600  -28.42700 -32.45400 1.000 38.23000  ? 167 ARG A HH12 1 
ATOM   2593 H  HH21 . ARG A 1 167 ? 15.46100  -31.33800 -32.13400 1.000 41.28000  ? 167 ARG A HH21 1 
ATOM   2594 H  HH22 . ARG A 1 167 ? 14.74900  -30.27100 -31.37600 1.000 41.28000  ? 167 ARG A HH22 1 
ATOM   2595 N  N    . GLU A 1 168 ? 19.19100  -30.77100 -33.29700 1.000 26.02417  ? 168 GLU A N    1 
ATOM   2596 C  CA   . GLU A 1 168 ? 19.04900  -31.10900 -31.88400 1.000 24.75034  ? 168 GLU A CA   1 
ATOM   2597 C  C    . GLU A 1 168 ? 20.13200  -30.45500 -31.04200 1.000 28.40341  ? 168 GLU A C    1 
ATOM   2598 O  O    . GLU A 1 168 ? 19.86100  -29.95400 -29.93100 1.000 27.12694  ? 168 GLU A O    1 
ATOM   2599 C  CB   . GLU A 1 168 ? 19.09000  -32.62600 -31.72200 1.000 24.95036  ? 168 GLU A CB   1 
ATOM   2600 C  CG   . GLU A 1 168 ? 18.77500  -33.09900 -30.29100 1.000 29.81410  ? 168 GLU A CG   1 
ATOM   2601 C  CD   . GLU A 1 168 ? 17.29500  -33.13400 -29.97900 1.000 33.82511  ? 168 GLU A CD   1 
ATOM   2602 O  OE1  . GLU A 1 168 ? 16.47000  -32.80100 -30.83400 1.000 29.21929  ? 168 GLU A OE1  1 
ATOM   2603 O  OE2  . GLU A 1 168 ? 16.96100  -33.51000 -28.83500 1.000 32.05121  ? 168 GLU A OE2  1 
ATOM   2604 H  H    . GLU A 1 168 ? 19.37000  -31.43900 -33.80900 1.000 31.23000  ? 168 GLU A H    1 
ATOM   2605 H  HA   . GLU A 1 168 ? 18.19300  -30.78500 -31.56400 1.000 29.70000  ? 168 GLU A HA   1 
ATOM   2606 H  HB2  . GLU A 1 168 ? 18.43500  -33.02200 -32.31800 1.000 29.94000  ? 168 GLU A HB2  1 
ATOM   2607 H  HB3  . GLU A 1 168 ? 19.97900  -32.94100 -31.95100 1.000 29.94000  ? 168 GLU A HB3  1 
ATOM   2608 H  HG2  . GLU A 1 168 ? 19.12400  -33.99600 -30.17300 1.000 35.78000  ? 168 GLU A HG2  1 
ATOM   2609 H  HG3  . GLU A 1 168 ? 19.19600  -32.49300 -29.66100 1.000 35.78000  ? 168 GLU A HG3  1 
ATOM   2610 N  N    . THR A 1 169 ? 21.37100  -30.47100 -31.53100 1.000 26.43738  ? 169 THR A N    1 
ATOM   2611 C  CA   . THR A 1 169 ? 22.46900  -29.83800 -30.81300 1.000 27.50856  ? 169 THR A CA   1 
ATOM   2612 C  C    . THR A 1 169 ? 22.19900  -28.34800 -30.64100 1.000 29.80094  ? 169 THR A C    1 
ATOM   2613 O  O    . THR A 1 169 ? 22.33200  -27.80000 -29.54500 1.000 29.26404  ? 169 THR A O    1 
ATOM   2614 C  CB   . THR A 1 169 ? 23.78000  -30.07600 -31.55900 1.000 25.66097  ? 169 THR A CB   1 
ATOM   2615 O  OG1  . THR A 1 169 ? 24.04200  -31.49000 -31.64600 1.000 27.29801  ? 169 THR A OG1  1 
ATOM   2616 C  CG2  . THR A 1 169 ? 24.96300  -29.41400 -30.83200 1.000 27.24011  ? 169 THR A CG2  1 
ATOM   2617 H  H    . THR A 1 169 ? 21.59900  -30.84000 -32.27400 1.000 31.72000  ? 169 THR A H    1 
ATOM   2618 H  HA   . THR A 1 169 ? 22.55400  -30.23500 -29.93200 1.000 33.01000  ? 169 THR A HA   1 
ATOM   2619 H  HB   . THR A 1 169 ? 23.70400  -29.69100 -32.44600 1.000 30.80000  ? 169 THR A HB   1 
ATOM   2620 H  HG1  . THR A 1 169 ? 23.41200  -31.87400 -32.04700 1.000 32.76000  ? 169 THR A HG1  1 
ATOM   2621 H  HG21 . THR A 1 169 ? 25.79500  -29.83800 -31.09700 1.000 32.69000  ? 169 THR A HG21 1 
ATOM   2622 H  HG22 . THR A 1 169 ? 25.00500  -28.47100 -31.05600 1.000 32.69000  ? 169 THR A HG22 1 
ATOM   2623 H  HG23 . THR A 1 169 ? 24.85600  -29.50500 -29.87200 1.000 32.69000  ? 169 THR A HG23 1 
ATOM   2624 N  N    . MET A 1 170 ? 21.79200  -27.67700 -31.72000 1.000 26.52160  ? 170 MET A N    1 
ATOM   2625 C  CA   . MET A 1 170 ? 21.47000  -26.25600 -31.61300 1.000 28.59027  ? 170 MET A CA   1 
ATOM   2626 C  C    . MET A 1 170 ? 20.35400  -26.03300 -30.59500 1.000 30.23520  ? 170 MET A C    1 
ATOM   2627 O  O    . MET A 1 170 ? 20.38700  -25.07400 -29.80800 1.000 30.12730  ? 170 MET A O    1 
ATOM   2628 C  CB   . MET A 1 170 ? 21.05800  -25.72300 -32.98200 1.000 30.14572  ? 170 MET A CB   1 
ATOM   2629 C  CG   . MET A 1 170 ? 22.19400  -25.51500 -33.96800 1.000 31.02740  ? 170 MET A CG   1 
ATOM   2630 S  SD   . MET A 1 170 ? 23.81600  -24.98000 -33.45400 1.000 31.15110  ? 170 MET A SD   1 
ATOM   2631 C  CE   . MET A 1 170 ? 23.50600  -23.18200 -33.39200 1.000 29.62987  ? 170 MET A CE   1 
ATOM   2632 H  H    . MET A 1 170 ? 21.69700  -28.01300 -32.50600 1.000 31.83000  ? 170 MET A H    1 
ATOM   2633 H  HA   . MET A 1 170 ? 22.25900  -25.77000 -31.32700 1.000 34.31000  ? 170 MET A HA   1 
ATOM   2634 H  HB2  . MET A 1 170 ? 20.43900  -26.35400 -33.38200 1.000 36.17000  ? 170 MET A HB2  1 
ATOM   2635 H  HB3  . MET A 1 170 ? 20.62300  -24.86500 -32.85700 1.000 36.17000  ? 170 MET A HB3  1 
ATOM   2636 H  HG2  . MET A 1 170 ? 22.33300  -26.36400 -34.41700 1.000 37.23000  ? 170 MET A HG2  1 
ATOM   2637 H  HG3  . MET A 1 170 ? 21.89200  -24.84900 -34.60500 1.000 37.23000  ? 170 MET A HG3  1 
ATOM   2638 H  HE1  . MET A 1 170 ? 24.32600  -22.72800 -33.14100 1.000 35.55000  ? 170 MET A HE1  1 
ATOM   2639 H  HE2  . MET A 1 170 ? 23.21700  -22.88100 -34.26800 1.000 35.55000  ? 170 MET A HE2  1 
ATOM   2640 H  HE3  . MET A 1 170 ? 22.81400  -23.00300 -32.73600 1.000 35.55000  ? 170 MET A HE3  1 
ATOM   2641 N  N    . SER A 1 171 ? 19.36200  -26.91700 -30.58400 1.000 27.78228  ? 171 SER A N    1 
ATOM   2642 C  CA   . SER A 1 171 ? 18.26300  -26.78000 -29.63400 1.000 28.79293  ? 171 SER A CA   1 
ATOM   2643 C  C    . SER A 1 171 ? 18.76600  -26.79900 -28.19100 1.000 32.87499  ? 171 SER A C    1 
ATOM   2644 O  O    . SER A 1 171 ? 18.31600  -26.00300 -27.35700 1.000 33.02764  ? 171 SER A O    1 
ATOM   2645 C  CB   . SER A 1 171 ? 17.25700  -27.90100 -29.87500 1.000 31.96436  ? 171 SER A CB   1 
ATOM   2646 O  OG   . SER A 1 171 ? 16.08200  -27.69000 -29.12200 1.000 46.15027  ? 171 SER A OG   1 
ATOM   2647 H  H    . SER A 1 171 ? 19.30100  -27.59600 -31.10900 1.000 33.34000  ? 171 SER A H    1 
ATOM   2648 H  HA   . SER A 1 171 ? 17.81900  -25.92900 -29.77300 1.000 34.55000  ? 171 SER A HA   1 
ATOM   2649 H  HB2  . SER A 1 171 ? 17.02900  -27.92400 -30.81700 1.000 38.36000  ? 171 SER A HB2  1 
ATOM   2650 H  HB3  . SER A 1 171 ? 17.65500  -28.74500 -29.60900 1.000 38.36000  ? 171 SER A HB3  1 
ATOM   2651 H  HG   . SER A 1 171 ? 15.52000  -28.29000 -29.29300 1.000 55.38000  ? 171 SER A HG   1 
ATOM   2652 N  N    . TYR A 1 172 ? 19.68900  -27.70500 -27.87800 1.000 30.84580  ? 172 TYR A N    1 
ATOM   2653 C  CA   . TYR A 1 172 ? 20.26600  -27.74700 -26.53500 1.000 29.95096  ? 172 TYR A CA   1 
ATOM   2654 C  C    . TYR A 1 172 ? 21.03900  -26.47900 -26.21500 1.000 31.97489  ? 172 TYR A C    1 
ATOM   2655 O  O    . TYR A 1 172 ? 20.97000  -25.96100 -25.09200 1.000 33.63824  ? 172 TYR A O    1 
ATOM   2656 C  CB   . TYR A 1 172 ? 21.21500  -28.94200 -26.41800 1.000 34.53835  ? 172 TYR A CB   1 
ATOM   2657 C  CG   . TYR A 1 172 ? 20.56300  -30.20800 -25.96300 1.000 36.89390  ? 172 TYR A CG   1 
ATOM   2658 C  CD1  . TYR A 1 172 ? 20.36000  -30.44400 -24.60800 1.000 39.38367  ? 172 TYR A CD1  1 
ATOM   2659 C  CD2  . TYR A 1 172 ? 20.16300  -31.17300 -26.86800 1.000 40.42590  ? 172 TYR A CD2  1 
ATOM   2660 C  CE1  . TYR A 1 172 ? 19.76100  -31.61000 -24.17900 1.000 49.22959  ? 172 TYR A CE1  1 
ATOM   2661 C  CE2  . TYR A 1 172 ? 19.56400  -32.34200 -26.45200 1.000 43.23150  ? 172 TYR A CE2  1 
ATOM   2662 C  CZ   . TYR A 1 172 ? 19.37200  -32.55600 -25.10000 1.000 42.86830  ? 172 TYR A CZ   1 
ATOM   2663 O  OH   . TYR A 1 172 ? 18.77100  -33.72300 -24.69700 1.000 38.07562  ? 172 TYR A OH   1 
ATOM   2664 H  H    A TYR A 1 172 ? 19.99700  -28.30100 -28.41700 0.360 37.02000  ? 172 TYR A H    1 
ATOM   2665 H  H    B TYR A 1 172 ? 19.99700  -28.30100 -28.41700 0.640 37.02000  ? 172 TYR A H    1 
ATOM   2666 H  HA   . TYR A 1 172 ? 19.53900  -27.84100 -25.89800 1.000 35.94000  ? 172 TYR A HA   1 
ATOM   2667 H  HB2  . TYR A 1 172 ? 21.60700  -29.11100 -27.28900 1.000 41.44000  ? 172 TYR A HB2  1 
ATOM   2668 H  HB3  . TYR A 1 172 ? 21.91000  -28.72400 -25.77800 1.000 41.44000  ? 172 TYR A HB3  1 
ATOM   2669 H  HD1  . TYR A 1 172 ? 20.63200  -29.81000 -23.98400 1.000 47.26000  ? 172 TYR A HD1  1 
ATOM   2670 H  HD2  . TYR A 1 172 ? 20.30200  -31.03100 -27.77600 1.000 48.51000  ? 172 TYR A HD2  1 
ATOM   2671 H  HE1  . TYR A 1 172 ? 19.62100  -31.75600 -23.27200 1.000 59.08000  ? 172 TYR A HE1  1 
ATOM   2672 H  HE2  . TYR A 1 172 ? 19.29200  -32.97900 -27.07300 1.000 51.88000  ? 172 TYR A HE2  1 
ATOM   2673 H  HH   . TYR A 1 172 ? 18.62100  -34.21400 -25.36100 1.000 45.69000  ? 172 TYR A HH   1 
ATOM   2674 N  N    . LEU A 1 173 ? 21.83800  -26.00500 -27.16400 1.000 30.53524  ? 173 LEU A N    1 
ATOM   2675 C  CA   . LEU A 1 173 ? 22.62100  -24.79600 -26.93600 1.000 31.50641  ? 173 LEU A CA   1 
ATOM   2676 C  C    . LEU A 1 173 ? 21.69900  -23.59600 -26.72100 1.000 33.58561  ? 173 LEU A C    1 
ATOM   2677 O  O    . LEU A 1 173 ? 21.91500  -22.79600 -25.80600 1.000 33.05133  ? 173 LEU A O    1 
ATOM   2678 C  CB   . LEU A 1 173 ? 23.56900  -24.59700 -28.12100 1.000 32.25913  ? 173 LEU A CB   1 
ATOM   2679 C  CG   . LEU A 1 173 ? 24.68000  -25.67000 -28.18700 1.000 31.79329  ? 173 LEU A CG   1 
ATOM   2680 C  CD1  . LEU A 1 173 ? 25.56000  -25.51800 -29.40400 1.000 39.66002  ? 173 LEU A CD1  1 
ATOM   2681 C  CD2  . LEU A 1 173 ? 25.52600  -25.66600 -26.90400 1.000 42.81566  ? 173 LEU A CD2  1 
ATOM   2682 H  H    . LEU A 1 173 ? 21.94400  -26.35900 -27.94000 1.000 36.64000  ? 173 LEU A H    1 
ATOM   2683 H  HA   . LEU A 1 173 ? 23.16500  -24.88000 -26.13700 1.000 37.81000  ? 173 LEU A HA   1 
ATOM   2684 H  HB2  . LEU A 1 173 ? 23.05800  -24.64200 -28.94400 1.000 38.71000  ? 173 LEU A HB2  1 
ATOM   2685 H  HB3  . LEU A 1 173 ? 23.99300  -23.72800 -28.04200 1.000 38.71000  ? 173 LEU A HB3  1 
ATOM   2686 H  HG   . LEU A 1 173 ? 24.24300  -26.53200 -28.26300 1.000 38.15000  ? 173 LEU A HG   1 
ATOM   2687 H  HD11 . LEU A 1 173 ? 26.26600  -26.18200 -29.36800 1.000 47.59000  ? 173 LEU A HD11 1 
ATOM   2688 H  HD12 . LEU A 1 173 ? 25.02300  -25.64900 -30.20100 1.000 47.59000  ? 173 LEU A HD12 1 
ATOM   2689 H  HD13 . LEU A 1 173 ? 25.94300  -24.62700 -29.40700 1.000 47.59000  ? 173 LEU A HD13 1 
ATOM   2690 H  HD21 . LEU A 1 173 ? 26.35600  -26.13900 -27.07200 1.000 51.38000  ? 173 LEU A HD21 1 
ATOM   2691 H  HD22 . LEU A 1 173 ? 25.71300  -24.74800 -26.65200 1.000 51.38000  ? 173 LEU A HD22 1 
ATOM   2692 H  HD23 . LEU A 1 173 ? 25.03000  -26.10900 -26.19800 1.000 51.38000  ? 173 LEU A HD23 1 
ATOM   2693 N  N    . PHE A 1 174 ? 20.61400  -23.51100 -27.48000 1.000 31.38797  ? 174 PHE A N    1 
ATOM   2694 C  CA   . PHE A 1 174 ? 19.63900  -22.39900 -27.38900 1.000 30.88528  ? 174 PHE A CA   1 
ATOM   2695 C  C    . PHE A 1 174 ? 18.90000  -22.46300 -26.04700 1.000 34.00934  ? 174 PHE A C    1 
ATOM   2696 O  O    . PHE A 1 174 ? 18.50900  -21.41000 -25.56900 1.000 33.87511  ? 174 PHE A O    1 
ATOM   2697 C  CB   . PHE A 1 174 ? 18.69200  -22.46500 -28.58700 1.000 30.61157  ? 174 PHE A CB   1 
ATOM   2698 C  CG   . PHE A 1 174 ? 19.27400  -22.11800 -29.93500 1.000 32.73814  ? 174 PHE A CG   1 
ATOM   2699 C  CD1  . PHE A 1 174 ? 20.46700  -21.42500 -30.07200 1.000 33.25925  ? 174 PHE A CD1  1 
ATOM   2700 C  CD2  . PHE A 1 174 ? 18.59600  -22.48300 -31.08500 1.000 33.36189  ? 174 PHE A CD2  1 
ATOM   2701 C  CE1  . PHE A 1 174 ? 20.96700  -21.11700 -31.32500 1.000 37.09129  ? 174 PHE A CE1  1 
ATOM   2702 C  CE2  . PHE A 1 174 ? 19.09800  -22.17300 -32.33700 1.000 30.12730  ? 174 PHE A CE2  1 
ATOM   2703 C  CZ   . PHE A 1 174 ? 20.28200  -21.49000 -32.45500 1.000 34.75154  ? 174 PHE A CZ   1 
ATOM   2704 H  H    . PHE A 1 174 ? 20.36500  -24.14200 -28.08500 1.000 37.67000  ? 174 PHE A H    1 
ATOM   2705 H  HA   . PHE A 1 174 ? 20.13300  -21.54200 -27.42000 1.000 37.06000  ? 174 PHE A HA   1 
ATOM   2706 H  HB2  . PHE A 1 174 ? 18.33100  -23.37500 -28.63400 1.000 36.73000  ? 174 PHE A HB2  1 
ATOM   2707 H  HB3  . PHE A 1 174 ? 17.94000  -21.86300 -28.41100 1.000 36.73000  ? 174 PHE A HB3  1 
ATOM   2708 H  HD1  . PHE A 1 174 ? 20.94800  -21.15900 -29.30600 1.000 39.91000  ? 174 PHE A HD1  1 
ATOM   2709 H  HD2  . PHE A 1 174 ? 17.78100  -22.95100 -31.01200 1.000 40.03000  ? 174 PHE A HD2  1 
ATOM   2710 H  HE1  . PHE A 1 174 ? 21.78300  -20.64600 -31.40300 1.000 44.51000  ? 174 PHE A HE1  1 
ATOM   2711 H  HE2  . PHE A 1 174 ? 18.62400  -22.43200 -33.11100 1.000 36.15000  ? 174 PHE A HE2  1 
ATOM   2712 H  HZ   . PHE A 1 174 ? 20.62600  -21.28000 -33.30900 1.000 41.70000  ? 174 PHE A HZ   1 
ATOM   2713 N  N    . GLN A 1 175 ? 18.70100  -23.64900 -25.48100 1.000 31.13531  ? 175 GLN A N    1 
ATOM   2714 C  CA   . GLN A 1 175 ? 18.04500  -23.82400 -24.16200 1.000 35.59374  ? 175 GLN A CA   1 
ATOM   2715 C  C    . GLN A 1 175 ? 18.96400  -23.29600 -23.05800 1.000 34.69363  ? 175 GLN A C    1 
ATOM   2716 O  O    . GLN A 1 175 ? 18.45000  -23.02800 -21.97400 1.000 34.37517  ? 175 GLN A O    1 
ATOM   2717 C  CB   . GLN A 1 175 ? 17.70700  -25.29200 -23.94600 1.000 39.26260  ? 175 GLN A CB   1 
ATOM   2718 C  CG   . GLN A 1 175 ? 16.31700  -25.62700 -24.44700 1.000 48.91113  ? 175 GLN A CG   1 
ATOM   2719 C  CD   . GLN A 1 175 ? 16.11600  -27.09500 -24.71200 1.000 66.32111  ? 175 GLN A CD   1 
ATOM   2720 O  OE1  . GLN A 1 175 ? 16.87300  -27.94600 -24.25100 1.000 74.90109  ? 175 GLN A OE1  1 
ATOM   2721 N  NE2  . GLN A 1 175 ? 15.07500  -27.39500 -25.46800 1.000 79.57533  ? 175 GLN A NE2  1 
ATOM   2722 H  H    . GLN A 1 175 ? 18.95300  -24.43500 -25.87100 1.000 37.36000  ? 175 GLN A H    1 
ATOM   2723 H  HA   . GLN A 1 175 ? 17.21100  -23.30600 -24.15700 1.000 42.71000  ? 175 GLN A HA   1 
ATOM   2724 H  HB2  . GLN A 1 175 ? 18.36700  -25.83900 -24.41800 1.000 47.11000  ? 175 GLN A HB2  1 
ATOM   2725 H  HB3  . GLN A 1 175 ? 17.76900  -25.49500 -22.99100 1.000 47.11000  ? 175 GLN A HB3  1 
ATOM   2726 H  HG2  . GLN A 1 175 ? 15.65900  -25.32900 -23.78600 1.000 58.69000  ? 175 GLN A HG2  1 
ATOM   2727 H  HG3  . GLN A 1 175 ? 16.15200  -25.12900 -25.27700 1.000 58.69000  ? 175 GLN A HG3  1 
ATOM   2728 H  HE21 . GLN A 1 175 ? 14.85100  -26.86600 -26.14000 1.000 95.49000  ? 175 GLN A HE21 1 
ATOM   2729 H  HE22 . GLN A 1 175 ? 14.60500  -28.12500 -25.30300 1.000 95.49000  ? 175 GLN A HE22 1 
ATOM   2730 N  N    . HIS A 1 176 ? 20.26200  -23.17500 -23.32800 1.000 30.34048  ? 176 HIS A N    1 
ATOM   2731 C  CA   . HIS A 1 176 ? 21.25500  -22.63600 -22.36900 1.000 34.23568  ? 176 HIS A CA   1 
ATOM   2732 C  C    . HIS A 1 176 ? 21.67800  -21.25200 -22.86400 1.000 31.35639  ? 176 HIS A C    1 
ATOM   2733 O  O    . HIS A 1 176 ? 22.80900  -20.93000 -22.63700 1.000 32.40652  ? 176 HIS A O    1 
ATOM   2734 C  CB   . HIS A 1 176 ? 22.42900  -23.61400 -22.22000 1.000 30.93792  ? 176 HIS A CB   1 
ATOM   2735 C  CG   . HIS A 1 176 ? 22.13100  -24.82400 -21.40900 1.000 39.31787  ? 176 HIS A CG   1 
ATOM   2736 N  ND1  . HIS A 1 176 ? 21.61700  -25.98400 -21.93700 1.000 41.92608  ? 176 HIS A ND1  1 
ATOM   2737 C  CD2  . HIS A 1 176 ? 22.30700  -25.06100 -20.11000 1.000 41.12598  ? 176 HIS A CD2  1 
ATOM   2738 C  CE1  . HIS A 1 176 ? 21.47800  -26.87800 -20.97700 1.000 38.48619  ? 176 HIS A CE1  1 
ATOM   2739 N  NE2  . HIS A 1 176 ? 21.89300  -26.33900 -19.86000 1.000 38.57831  ? 176 HIS A NE2  1 
ATOM   2740 H  H    . HIS A 1 176 ? 20.61900  -23.44700 -24.11000 1.000 36.41000  ? 176 HIS A H    1 
ATOM   2741 H  HA   . HIS A 1 176 ? 20.82900  -22.52900 -21.48900 1.000 41.09000  ? 176 HIS A HA   1 
ATOM   2742 H  HB2  . HIS A 1 176 ? 22.71300  -23.89600 -23.11700 1.000 37.13000  ? 176 HIS A HB2  1 
ATOM   2743 H  HB3  . HIS A 1 176 ? 23.18400  -23.14900 -21.80200 1.000 37.13000  ? 176 HIS A HB3  1 
ATOM   2744 H  HD1  . HIS A 1 176 ? 21.40600  -26.11000 -22.76500 1.000 50.31000  ? 176 HIS A HD1  1 
ATOM   2745 H  HD2  . HIS A 1 176 ? 22.65300  -24.46700 -19.47500 1.000 49.35000  ? 176 HIS A HD2  1 
ATOM   2746 H  HE1  . HIS A 1 176 ? 21.14000  -27.75000 -21.08100 1.000 46.18000  ? 176 HIS A HE1  1 
ATOM   2747 N  N    . ALA A 1 177 ? 20.83200  -20.53400 -23.60000 1.000 31.56694  ? 177 ALA A N    1 
ATOM   2748 C  CA   . ALA A 1 177 ? 21.11600  -19.20200 -24.09800 1.000 29.33773  ? 177 ALA A CA   1 
ATOM   2749 C  C    . ALA A 1 177 ? 20.02000  -18.24100 -23.66100 1.000 33.48823  ? 177 ALA A C    1 
ATOM   2750 O  O    . ALA A 1 177 ? 18.91800  -18.65600 -23.28700 1.000 31.23532  ? 177 ALA A O    1 
ATOM   2751 C  CB   . ALA A 1 177 ? 21.22400  -19.21400 -25.64000 1.000 29.83252  ? 177 ALA A CB   1 
ATOM   2752 H  H    . ALA A 1 177 ? 20.07700  -20.84200 -23.87300 1.000 37.88000  ? 177 ALA A H    1 
ATOM   2753 H  HA   . ALA A 1 177 ? 21.95400  -18.88300 -23.73000 1.000 35.20000  ? 177 ALA A HA   1 
ATOM   2754 H  HB1  . ALA A 1 177 ? 21.42700  -18.31700 -25.94900 1.000 35.80000  ? 177 ALA A HB1  1 
ATOM   2755 H  HB2  . ALA A 1 177 ? 21.93200  -19.82300 -25.90200 1.000 35.80000  ? 177 ALA A HB2  1 
ATOM   2756 H  HB3  . ALA A 1 177 ? 20.37900  -19.50800 -26.01400 1.000 35.80000  ? 177 ALA A HB3  1 
ATOM   2757 N  N    . ASN A 1 178 ? 20.32600  -16.94800 -23.69100 1.000 32.87236  ? 178 ASN A N    1 
ATOM   2758 C  CA   . ASN A 1 178 ? 19.33900  -15.94900 -23.30500 1.000 34.17515  ? 178 ASN A CA   1 
ATOM   2759 C  C    . ASN A 1 178 ? 18.59100  -15.53600 -24.56500 1.000 35.62532  ? 178 ASN A C    1 
ATOM   2760 O  O    . ASN A 1 178 ? 19.05400  -14.67500 -25.31900 1.000 35.66743  ? 178 ASN A O    1 
ATOM   2761 C  CB   . ASN A 1 178 ? 19.96100  -14.72300 -22.66200 1.000 41.38917  ? 178 ASN A CB   1 
ATOM   2762 C  CG   . ASN A 1 178 ? 18.92100  -13.64300 -22.37700 1.000 54.89342  ? 178 ASN A CG   1 
ATOM   2763 O  OD1  . ASN A 1 178 ? 17.70900  -13.91000 -22.38500 1.000 46.10553  ? 178 ASN A OD1  1 
ATOM   2764 N  ND2  . ASN A 1 178 ? 19.38500  -12.41000 -22.18200 1.000 70.54530  ? 178 ASN A ND2  1 
ATOM   2765 H  H    . ASN A 1 178 ? 21.08900  -16.63000 -23.92900 1.000 39.45000  ? 178 ASN A H    1 
ATOM   2766 H  HA   . ASN A 1 178 ? 18.74100  -16.35700 -22.65900 1.000 41.01000  ? 178 ASN A HA   1 
ATOM   2767 H  HB2  . ASN A 1 178 ? 20.37400  -14.97700 -21.82200 1.000 49.67000  ? 178 ASN A HB2  1 
ATOM   2768 H  HB3  . ASN A 1 178 ? 20.62900  -14.35200 -23.26000 1.000 49.67000  ? 178 ASN A HB3  1 
ATOM   2769 H  HD21 . ASN A 1 178 ? 20.23000  -12.25800 -22.22000 1.000 84.65000  ? 178 ASN A HD21 1 
ATOM   2770 H  HD22 . ASN A 1 178 ? 18.83900  -11.76700 -22.01800 1.000 84.65000  ? 178 ASN A HD22 1 
ATOM   2771 N  N    . LEU A 1 179 ? 17.41800  -16.12500 -24.78000 1.000 33.15398  ? 179 LEU A N    1 
ATOM   2772 C  CA   . LEU A 1 179 ? 16.57500  -15.80700 -25.92900 1.000 31.45377  ? 179 LEU A CA   1 
ATOM   2773 C  C    . LEU A 1 179 ? 15.24700  -15.20000 -25.49100 1.000 31.93804  ? 179 LEU A C    1 
ATOM   2774 O  O    . LEU A 1 179 ? 14.26500  -15.26100 -26.22600 1.000 33.96197  ? 179 LEU A O    1 
ATOM   2775 C  CB   . LEU A 1 179 ? 16.34600  -17.06900 -26.75100 1.000 32.42757  ? 179 LEU A CB   1 
ATOM   2776 C  CG   . LEU A 1 179 ? 17.61300  -17.65500 -27.37000 1.000 34.63573  ? 179 LEU A CG   1 
ATOM   2777 C  CD1  . LEU A 1 179 ? 17.31300  -19.02700 -27.95200 1.000 31.75118  ? 179 LEU A CD1  1 
ATOM   2778 C  CD2  . LEU A 1 179 ? 18.16400  -16.73800 -28.44700 1.000 37.63872  ? 179 LEU A CD2  1 
ATOM   2779 H  H    . LEU A 1 179 ? 17.08200  -16.72500 -24.26300 1.000 39.78000  ? 179 LEU A H    1 
ATOM   2780 H  HA   . LEU A 1 179 ? 17.02000  -15.15400 -26.49200 1.000 37.75000  ? 179 LEU A HA   1 
ATOM   2781 H  HB2  . LEU A 1 179 ? 15.95900  -17.74700 -26.17500 1.000 38.91000  ? 179 LEU A HB2  1 
ATOM   2782 H  HB3  . LEU A 1 179 ? 15.73400  -16.86000 -27.47400 1.000 38.91000  ? 179 LEU A HB3  1 
ATOM   2783 H  HG   . LEU A 1 179 ? 18.29000  -17.74400 -26.68200 1.000 41.56000  ? 179 LEU A HG   1 
ATOM   2784 H  HD11 . LEU A 1 179 ? 18.12700  -19.39200 -28.33500 1.000 38.10000  ? 179 LEU A HD11 1 
ATOM   2785 H  HD12 . LEU A 1 179 ? 16.99200  -19.60700 -27.24400 1.000 38.10000  ? 179 LEU A HD12 1 
ATOM   2786 H  HD13 . LEU A 1 179 ? 16.63500  -18.93800 -28.63900 1.000 38.10000  ? 179 LEU A HD13 1 
ATOM   2787 H  HD21 . LEU A 1 179 ? 18.90200  -17.18300 -28.89300 1.000 45.17000  ? 179 LEU A HD21 1 
ATOM   2788 H  HD22 . LEU A 1 179 ? 17.46100  -16.54400 -29.08600 1.000 45.17000  ? 179 LEU A HD22 1 
ATOM   2789 H  HD23 . LEU A 1 179 ? 18.47300  -15.91700 -28.03500 1.000 45.17000  ? 179 LEU A HD23 1 
ATOM   2790 N  N    . ASP A 1 180 ? 15.18700  -14.64600 -24.28500 1.000 34.85944  ? 180 ASP A N    1 
ATOM   2791 C  CA   . ASP A 1 180 ? 13.91300  -14.16000 -23.76700 1.000 36.97285  ? 180 ASP A CA   1 
ATOM   2792 C  C    . ASP A 1 180 ? 13.41200  -12.91800 -24.50100 1.000 38.33354  ? 180 ASP A C    1 
ATOM   2793 O  O    . ASP A 1 180 ? 12.23600  -12.56400 -24.34500 1.000 43.46311  ? 180 ASP A O    1 
ATOM   2794 C  CB   . ASP A 1 180 ? 14.04800  -13.87500 -22.28000 1.000 39.02573  ? 180 ASP A CB   1 
ATOM   2795 C  CG   . ASP A 1 180 ? 14.06700  -15.14400 -21.45100 1.000 41.95766  ? 180 ASP A CG   1 
ATOM   2796 O  OD1  . ASP A 1 180 ? 13.71000  -16.22000 -21.97800 1.000 38.22300  ? 180 ASP A OD1  1 
ATOM   2797 O  OD2  . ASP A 1 180 ? 14.44100  -15.05400 -20.26800 1.000 44.36585  ? 180 ASP A OD2  1 
ATOM   2798 H  H    . ASP A 1 180 ? 15.85700  -14.54200 -23.75600 1.000 41.83000  ? 180 ASP A H    1 
ATOM   2799 H  HA   . ASP A 1 180 ? 13.23900  -14.84900 -23.88000 1.000 44.37000  ? 180 ASP A HA   1 
ATOM   2800 H  HB2  . ASP A 1 180 ? 14.87800  -13.39800 -22.12200 1.000 46.83000  ? 180 ASP A HB2  1 
ATOM   2801 H  HB3  . ASP A 1 180 ? 13.29500  -13.33600 -21.99000 1.000 46.83000  ? 180 ASP A HB3  1 
ATOM   2802 N  N    . SER A 1 181 ? 14.24900  -12.25000 -25.28900 1.000 36.17802  ? 181 SER A N    1 
ATOM   2803 C  CA   . SER A 1 181 ? 13.83300  -11.08100 -26.10600 1.000 38.07035  ? 181 SER A CA   1 
ATOM   2804 C  C    . SER A 1 181 ? 13.27100  -11.57600 -27.43500 1.000 38.97573  ? 181 SER A C    1 
ATOM   2805 O  O    . SER A 1 181 ? 12.76700  -10.74400 -28.19100 1.000 37.80716  ? 181 SER A O    1 
ATOM   2806 C  CB   . SER A 1 181 ? 14.95400  -10.12000 -26.32700 1.000 38.22564  ? 181 SER A CB   1 
ATOM   2807 O  OG   . SER A 1 181 ? 15.49400  -9.67300  -25.09600 1.000 48.42686  ? 181 SER A OG   1 
ATOM   2808 H  H    . SER A 1 181 ? 15.13800  -12.43500 -25.37500 1.000 43.41000  ? 181 SER A H    1 
ATOM   2809 H  HA   . SER A 1 181 ? 13.11000  -10.60300 -25.62300 1.000 45.68000  ? 181 SER A HA   1 
ATOM   2810 H  HB2  . SER A 1 181 ? 15.65600  -10.55700 -26.85800 1.000 45.87000  ? 181 SER A HB2  1 
ATOM   2811 H  HB3  . SER A 1 181 ? 14.62400  -9.34800  -26.83700 1.000 45.87000  ? 181 SER A HB3  1 
ATOM   2812 H  HG   . SER A 1 181 ? 16.07100  -10.23400 -24.83200 1.000 58.11000  ? 181 SER A HG   1 
ATOM   2813 N  N    . CYS A 1 182 ? 13.33700  -12.87800 -27.69700 1.000 32.07753  ? 182 CYS A N    1 
ATOM   2814 C  CA   . CYS A 1 182 ? 12.88800  -13.45300 -28.98600 1.000 32.98027  ? 182 CYS A CA   1 
ATOM   2815 C  C    . CYS A 1 182 ? 11.39400  -13.76000 -28.92600 1.000 36.57017  ? 182 CYS A C    1 
ATOM   2816 O  O    . CYS A 1 182 ? 10.96700  -14.38200 -27.97200 1.000 34.99893  ? 182 CYS A O    1 
ATOM   2817 C  CB   . CYS A 1 182 ? 13.67900  -14.68900 -29.39200 1.000 33.40401  ? 182 CYS A CB   1 
ATOM   2818 S  SG   . CYS A 1 182 ? 15.43000  -14.33900 -29.67200 1.000 34.24621  ? 182 CYS A SG   1 
ATOM   2819 H  H    . CYS A 1 182 ? 13.67800  -13.50000 -27.13300 1.000 38.49000  ? 182 CYS A H    1 
ATOM   2820 H  HA   . CYS A 1 182 ? 13.04200  -12.78700 -29.64600 1.000 39.58000  ? 182 CYS A HA   1 
ATOM   2821 H  HB2  . CYS A 1 182 ? 13.59900  -15.37000 -28.69600 1.000 40.08000  ? 182 CYS A HB2  1 
ATOM   2822 H  HB3  . CYS A 1 182 ? 13.29800  -15.05600 -30.21700 1.000 40.08000  ? 182 CYS A HB3  1 
ATOM   2823 H  HG   . CYS A 1 182 ? 15.75400  -15.46300 -29.94700 1.000 41.10000  ? 182 CYS A HG   1 
ATOM   2824 N  N    . LYS A 1 183 ? 10.64400  -13.30100 -29.91600 1.000 32.84341  ? 183 LYS A N    1 
ATOM   2825 C  CA   . LYS A 1 183 ? 9.19000   -13.54600 -29.98400 1.000 34.29622  ? 183 LYS A CA   1 
ATOM   2826 C  C    . LYS A 1 183 ? 8.79800   -13.89800 -31.40800 1.000 35.59901  ? 183 LYS A C    1 
ATOM   2827 O  O    . LYS A 1 183 ? 9.42400   -13.45900 -32.29500 1.000 34.59889  ? 183 LYS A O    1 
ATOM   2828 C  CB   . LYS A 1 183 ? 8.36700   -12.33700 -29.53700 1.000 35.62796  ? 183 LYS A CB   1 
ATOM   2829 C  CG   . LYS A 1 183 ? 6.86400   -12.56100 -29.59100 1.000 42.36034  ? 183 LYS A CG   1 
ATOM   2830 C  CD   . LYS A 1 183 ? 6.09700   -11.72200 -28.61200 1.000 46.60296  ? 183 LYS A CD   1 
ATOM   2831 C  CE   . LYS A 1 183 ? 5.79200   -10.34800 -29.15900 1.000 53.66959  ? 183 LYS A CE   1 
ATOM   2832 N  NZ   . LYS A 1 183 ? 4.43700   -10.30200 -29.75200 1.000 58.89917  ? 183 LYS A NZ   1 
ATOM   2833 H  H    . LYS A 1 183 ? 10.97400  -12.81300 -30.60700 1.000 39.41000  ? 183 LYS A H    1 
ATOM   2834 H  HA   . LYS A 1 183 ? 8.97000   -14.30900 -29.40700 1.000 41.16000  ? 183 LYS A HA   1 
ATOM   2835 H  HB2  . LYS A 1 183 ? 8.62000   -12.10900 -28.61900 1.000 42.76000  ? 183 LYS A HB2  1 
ATOM   2836 H  HB3  . LYS A 1 183 ? 8.59300   -11.57600 -30.11200 1.000 42.76000  ? 183 LYS A HB3  1 
ATOM   2837 H  HG2  . LYS A 1 183 ? 6.54500   -12.36100 -30.49700 1.000 50.83000  ? 183 LYS A HG2  1 
ATOM   2838 H  HG3  . LYS A 1 183 ? 6.67900   -13.50700 -29.41000 1.000 50.83000  ? 183 LYS A HG3  1 
ATOM   2839 H  HD2  . LYS A 1 183 ? 5.25300   -12.17200 -28.39400 1.000 55.92000  ? 183 LYS A HD2  1 
ATOM   2840 H  HD3  . LYS A 1 183 ? 6.61700   -11.63200 -27.78600 1.000 55.92000  ? 183 LYS A HD3  1 
ATOM   2841 H  HE2  . LYS A 1 183 ? 5.85100   -9.68800  -28.44400 1.000 64.40000  ? 183 LYS A HE2  1 
ATOM   2842 H  HE3  . LYS A 1 183 ? 6.44700   -10.11500 -29.84400 1.000 64.40000  ? 183 LYS A HE3  1 
ATOM   2843 H  HZ1  . LYS A 1 183 ? 4.37600   -9.60400  -30.32600 1.000 70.68000  ? 183 LYS A HZ1  1 
ATOM   2844 H  HZ2  . LYS A 1 183 ? 4.27700   -11.07300 -30.20200 1.000 70.68000  ? 183 LYS A HZ2  1 
ATOM   2845 H  HZ3  . LYS A 1 183 ? 3.81900   -10.21000 -29.09600 1.000 70.68000  ? 183 LYS A HZ3  1 
ATOM   2846 N  N    . ARG A 1 184 ? 7.82500   -14.74700 -31.57300 1.000 34.92787  ? 184 ARG A N    1 
ATOM   2847 C  CA   . ARG A 1 184 ? 7.29800   -15.15200 -32.86300 1.000 33.35400  ? 184 ARG A CA   1 
ATOM   2848 C  C    . ARG A 1 184 ? 5.78900   -15.24900 -32.74200 1.000 37.40712  ? 184 ARG A C    1 
ATOM   2849 O  O    . ARG A 1 184 ? 5.27200   -15.80500 -31.76600 1.000 35.72534  ? 184 ARG A O    1 
ATOM   2850 C  CB   . ARG A 1 184 ? 7.88900   -16.48200 -33.31800 1.000 32.97764  ? 184 ARG A CB   1 
ATOM   2851 C  CG   . ARG A 1 184 ? 7.12000   -17.12900 -34.43300 1.000 36.49385  ? 184 ARG A CG   1 
ATOM   2852 C  CD   . ARG A 1 184 ? 7.91200   -18.28300 -35.00500 1.000 34.28043  ? 184 ARG A CD   1 
ATOM   2853 N  NE   . ARG A 1 184 ? 9.10100   -17.77800 -35.68400 1.000 33.28557  ? 184 ARG A NE   1 
ATOM   2854 C  CZ   . ARG A 1 184 ? 10.06500  -18.54400 -36.17300 1.000 34.90682  ? 184 ARG A CZ   1 
ATOM   2855 N  NH1  . ARG A 1 184 ? 10.02000  -19.86000 -36.07000 1.000 33.23820  ? 184 ARG A NH1  1 
ATOM   2856 N  NH2  . ARG A 1 184 ? 11.10400  -17.97200 -36.76800 1.000 35.38056  ? 184 ARG A NH2  1 
ATOM   2857 H  H    . ARG A 1 184 ? 7.46300   -15.16100 -30.91100 1.000 41.91000  ? 184 ARG A H    1 
ATOM   2858 H  HA   . ARG A 1 184 ? 7.51800   -14.49100 -33.53800 1.000 40.03000  ? 184 ARG A HA   1 
ATOM   2859 H  HB2  . ARG A 1 184 ? 8.79500   -16.33100 -33.62900 1.000 39.57000  ? 184 ARG A HB2  1 
ATOM   2860 H  HB3  . ARG A 1 184 ? 7.89400   -17.09500 -32.56600 1.000 39.57000  ? 184 ARG A HB3  1 
ATOM   2861 H  HG2  . ARG A 1 184 ? 6.27600   -17.46700 -34.09600 1.000 43.79000  ? 184 ARG A HG2  1 
ATOM   2862 H  HG3  . ARG A 1 184 ? 6.96000   -16.48200 -35.13800 1.000 43.79000  ? 184 ARG A HG3  1 
ATOM   2863 H  HD2  . ARG A 1 184 ? 8.19000   -18.87600 -34.28900 1.000 41.13000  ? 184 ARG A HD2  1 
ATOM   2864 H  HD3  . ARG A 1 184 ? 7.36900   -18.76700 -35.64600 1.000 41.13000  ? 184 ARG A HD3  1 
ATOM   2865 H  HE   . ARG A 1 184 ? 9.18100   -16.92700 -35.77300 1.000 39.94000  ? 184 ARG A HE   1 
ATOM   2866 H  HH11 . ARG A 1 184 ? 9.35400   -20.23800 -35.67800 1.000 39.89000  ? 184 ARG A HH11 1 
ATOM   2867 H  HH12 . ARG A 1 184 ? 10.65600  -20.33900 -36.39500 1.000 39.89000  ? 184 ARG A HH12 1 
ATOM   2868 H  HH21 . ARG A 1 184 ? 11.14500  -17.11500 -36.83200 1.000 42.45000  ? 184 ARG A HH21 1 
ATOM   2869 H  HH22 . ARG A 1 184 ? 11.73600  -18.45800 -37.09000 1.000 42.45000  ? 184 ARG A HH22 1 
ATOM   2870 N  N    . VAL A 1 185 ? 5.08900   -14.67000 -33.71300 1.000 33.21714  ? 185 VAL A N    1 
ATOM   2871 C  CA   . VAL A 1 185 ? 3.64000   -14.78700 -33.81300 1.000 38.68885  ? 185 VAL A CA   1 
ATOM   2872 C  C    . VAL A 1 185 ? 3.32900   -15.45600 -35.13700 1.000 37.62293  ? 185 VAL A C    1 
ATOM   2873 O  O    . VAL A 1 185 ? 3.80200   -15.01400 -36.19300 1.000 35.78850  ? 185 VAL A O    1 
ATOM   2874 C  CB   . VAL A 1 185 ? 2.92800   -13.43100 -33.69400 1.000 40.24167  ? 185 VAL A CB   1 
ATOM   2875 C  CG1  . VAL A 1 185 ? 1.40800   -13.63500 -33.73900 1.000 38.78886  ? 185 VAL A CG1  1 
ATOM   2876 C  CG2  . VAL A 1 185 ? 3.31500   -12.75900 -32.37000 1.000 40.97333  ? 185 VAL A CG2  1 
ATOM   2877 H  H    . VAL A 1 185 ? 5.44000   -14.19500 -34.33800 1.000 39.86000  ? 185 VAL A H    1 
ATOM   2878 H  HA   . VAL A 1 185 ? 3.31200   -15.34600 -33.09200 1.000 46.43000  ? 185 VAL A HA   1 
ATOM   2879 H  HB   . VAL A 1 185 ? 3.19300   -12.86100 -34.43200 1.000 48.29000  ? 185 VAL A HB   1 
ATOM   2880 H  HG11 . VAL A 1 185 ? 0.97100   -12.79900 -33.51500 1.000 46.55000  ? 185 VAL A HG11 1 
ATOM   2881 H  HG12 . VAL A 1 185 ? 1.15300   -13.91200 -34.63300 1.000 46.55000  ? 185 VAL A HG12 1 
ATOM   2882 H  HG13 . VAL A 1 185 ? 1.16200   -14.32000 -33.09800 1.000 46.55000  ? 185 VAL A HG13 1 
ATOM   2883 H  HG21 . VAL A 1 185 ? 2.84800   -11.91200 -32.29700 1.000 49.17000  ? 185 VAL A HG21 1 
ATOM   2884 H  HG22 . VAL A 1 185 ? 3.06400   -13.34000 -31.63500 1.000 49.17000  ? 185 VAL A HG22 1 
ATOM   2885 H  HG23 . VAL A 1 185 ? 4.27400   -12.60900 -32.36100 1.000 49.17000  ? 185 VAL A HG23 1 
ATOM   2886 N  N    . LEU A 1 186 ? 2.56100   -16.53200 -35.06500 1.000 36.21487  ? 186 LEU A N    1 
ATOM   2887 C  CA   . LEU A 1 186 ? 2.17300   -17.33600 -36.21000 1.000 39.74950  ? 186 LEU A CA   1 
ATOM   2888 C  C    . LEU A 1 186 ? 0.66600   -17.25700 -36.37200 1.000 42.72354  ? 186 LEU A C    1 
ATOM   2889 O  O    . LEU A 1 186 ? -0.06900  -17.06200 -35.40200 1.000 40.31536  ? 186 LEU A O    1 
ATOM   2890 C  CB   . LEU A 1 186 ? 2.58300   -18.80700 -36.00800 1.000 38.72043  ? 186 LEU A CB   1 
ATOM   2891 C  CG   . LEU A 1 186 ? 4.07600   -19.07400 -35.90500 1.000 39.41525  ? 186 LEU A CG   1 
ATOM   2892 C  CD1  . LEU A 1 186 ? 4.37100   -20.56500 -35.89900 1.000 39.93637  ? 186 LEU A CD1  1 
ATOM   2893 C  CD2  . LEU A 1 186 ? 4.79900   -18.40000 -37.06200 1.000 42.05504  ? 186 LEU A CD2  1 
ATOM   2894 H  H    . LEU A 1 186 ? 2.23600   -16.83000 -34.32700 1.000 43.46000  ? 186 LEU A H    1 
ATOM   2895 H  HA   . LEU A 1 186 ? 2.60000   -17.00400 -37.01500 1.000 47.70000  ? 186 LEU A HA   1 
ATOM   2896 H  HB2  . LEU A 1 186 ? 2.17700   -19.12400 -35.18700 1.000 46.46000  ? 186 LEU A HB2  1 
ATOM   2897 H  HB3  . LEU A 1 186 ? 2.25100   -19.31900 -36.76200 1.000 46.46000  ? 186 LEU A HB3  1 
ATOM   2898 H  HG   . LEU A 1 186 ? 4.40400   -18.70800 -35.06900 1.000 47.30000  ? 186 LEU A HG   1 
ATOM   2899 H  HD11 . LEU A 1 186 ? 5.32800   -20.69700 -35.80900 1.000 47.92000  ? 186 LEU A HD11 1 
ATOM   2900 H  HD12 . LEU A 1 186 ? 3.90900   -20.97500 -35.15100 1.000 47.92000  ? 186 LEU A HD12 1 
ATOM   2901 H  HD13 . LEU A 1 186 ? 4.06100   -20.95200 -36.73200 1.000 47.92000  ? 186 LEU A HD13 1 
ATOM   2902 H  HD21 . LEU A 1 186 ? 5.68900   -18.77800 -37.14100 1.000 50.47000  ? 186 LEU A HD21 1 
ATOM   2903 H  HD22 . LEU A 1 186 ? 4.30000   -18.55500 -37.88000 1.000 50.47000  ? 186 LEU A HD22 1 
ATOM   2904 H  HD23 . LEU A 1 186 ? 4.85800   -17.44800 -36.88600 1.000 50.47000  ? 186 LEU A HD23 1 
ATOM   2905 N  N    . ASN A 1 187 ? 0.21000   -17.40300 -37.60600 1.000 38.73886  ? 187 ASN A N    1 
ATOM   2906 C  CA   . ASN A 1 187 ? -1.20400  -17.55800 -37.90000 1.000 43.55522  ? 187 ASN A CA   1 
ATOM   2907 C  C    . ASN A 1 187 ? -1.36900  -18.84900 -38.68400 1.000 41.63920  ? 187 ASN A C    1 
ATOM   2908 O  O    . ASN A 1 187 ? -0.59100  -19.12300 -39.60300 1.000 40.83121  ? 187 ASN A O    1 
ATOM   2909 C  CB   . ASN A 1 187 ? -1.74200  -16.36800 -38.68700 1.000 43.47890  ? 187 ASN A CB   1 
ATOM   2910 C  CG   . ASN A 1 187 ? -3.22900  -16.20600 -38.54100 1.000 48.81638  ? 187 ASN A CG   1 
ATOM   2911 O  OD1  . ASN A 1 187 ? -3.84200  -16.75600 -37.63100 1.000 48.44002  ? 187 ASN A OD1  1 
ATOM   2912 N  ND2  . ASN A 1 187 ? -3.82900  -15.45000 -39.44800 1.000 49.07167  ? 187 ASN A ND2  1 
ATOM   2913 H  H    . ASN A 1 187 ? 0.71200   -17.41500 -38.30400 1.000 46.49000  ? 187 ASN A H    1 
ATOM   2914 H  HA   . ASN A 1 187 ? -1.72100  -17.61400 -37.08100 1.000 52.27000  ? 187 ASN A HA   1 
ATOM   2915 H  HB2  . ASN A 1 187 ? -1.31800  -15.55700 -38.36500 1.000 52.18000  ? 187 ASN A HB2  1 
ATOM   2916 H  HB3  . ASN A 1 187 ? -1.54400  -16.49400 -39.62800 1.000 52.18000  ? 187 ASN A HB3  1 
ATOM   2917 H  HD21 . ASN A 1 187 ? -4.68000  -15.32500 -39.40900 1.000 58.89000  ? 187 ASN A HD21 1 
ATOM   2918 H  HD22 . ASN A 1 187 ? -3.36900  -15.08300 -40.07500 1.000 58.89000  ? 187 ASN A HD22 1 
ATOM   2919 N  N    . VAL A 1 188 ? -2.35200  -19.65100 -38.29900 1.000 40.82332  ? 188 VAL A N    1 
ATOM   2920 C  CA   . VAL A 1 188 ? -2.67900  -20.88700 -38.99400 1.000 41.46813  ? 188 VAL A CA   1 
ATOM   2921 C  C    . VAL A 1 188 ? -4.11400  -20.76700 -39.47200 1.000 46.25818  ? 188 VAL A C    1 
ATOM   2922 O  O    . VAL A 1 188 ? -5.04100  -20.66600 -38.65500 1.000 47.31883  ? 188 VAL A O    1 
ATOM   2923 C  CB   . VAL A 1 188 ? -2.49600  -22.12200 -38.10200 1.000 44.97118  ? 188 VAL A CB   1 
ATOM   2924 C  CG1  . VAL A 1 188 ? -2.89400  -23.37100 -38.86500 1.000 44.07634  ? 188 VAL A CG1  1 
ATOM   2925 C  CG2  . VAL A 1 188 ? -1.05000  -22.23400 -37.63000 1.000 42.75776  ? 188 VAL A CG2  1 
ATOM   2926 H  H    . VAL A 1 188 ? -2.85700  -19.49600 -37.62000 1.000 48.99000  ? 188 VAL A H    1 
ATOM   2927 H  HA   . VAL A 1 188 ? -2.09800  -20.99000 -39.76500 1.000 49.76000  ? 188 VAL A HA   1 
ATOM   2928 H  HB   . VAL A 1 188 ? -3.06400  -22.03500 -37.32000 1.000 53.97000  ? 188 VAL A HB   1 
ATOM   2929 H  HG11 . VAL A 1 188 ? -2.56800  -24.15000 -38.38800 1.000 52.89000  ? 188 VAL A HG11 1 
ATOM   2930 H  HG12 . VAL A 1 188 ? -3.86100  -23.40500 -38.93300 1.000 52.89000  ? 188 VAL A HG12 1 
ATOM   2931 H  HG13 . VAL A 1 188 ? -2.50100  -23.33700 -39.75200 1.000 52.89000  ? 188 VAL A HG13 1 
ATOM   2932 H  HG21 . VAL A 1 188 ? -0.96000  -23.02000 -37.06900 1.000 51.31000  ? 188 VAL A HG21 1 
ATOM   2933 H  HG22 . VAL A 1 188 ? -0.47000  -22.31200 -38.40400 1.000 51.31000  ? 188 VAL A HG22 1 
ATOM   2934 H  HG23 . VAL A 1 188 ? -0.82000  -21.43900 -37.12400 1.000 51.31000  ? 188 VAL A HG23 1 
ATOM   2935 N  N    . VAL A 1 189 ? -4.29500  -20.78800 -40.78800 1.000 43.18413  ? 189 VAL A N    1 
ATOM   2936 C  CA   . VAL A 1 189 ? -5.56900  -20.47800 -41.41600 1.000 47.53728  ? 189 VAL A CA   1 
ATOM   2937 C  C    . VAL A 1 189 ? -6.05800  -21.70800 -42.15400 1.000 45.99762  ? 189 VAL A C    1 
ATOM   2938 O  O    . VAL A 1 189 ? -5.41900  -22.16400 -43.11100 1.000 45.33438  ? 189 VAL A O    1 
ATOM   2939 C  CB   . VAL A 1 189 ? -5.46100  -19.29400 -42.38800 1.000 45.40018  ? 189 VAL A CB   1 
ATOM   2940 C  CG1  . VAL A 1 189 ? -6.83700  -18.96600 -42.94200 1.000 49.03483  ? 189 VAL A CG1  1 
ATOM   2941 C  CG2  . VAL A 1 189 ? -4.83600  -18.09500 -41.70800 1.000 46.28976  ? 189 VAL A CG2  1 
ATOM   2942 H  H    . VAL A 1 189 ? -3.67500  -20.98500 -41.35200 1.000 51.82000  ? 189 VAL A H    1 
ATOM   2943 H  HA   . VAL A 1 189 ? -6.20800  -20.26000 -40.71900 1.000 57.04000  ? 189 VAL A HA   1 
ATOM   2944 H  HB   . VAL A 1 189 ? -4.88200  -19.53000 -43.13000 1.000 54.48000  ? 189 VAL A HB   1 
ATOM   2945 H  HG11 . VAL A 1 189 ? -6.80800  -18.09500 -43.36700 1.000 58.84000  ? 189 VAL A HG11 1 
ATOM   2946 H  HG12 . VAL A 1 189 ? -7.08600  -19.64300 -43.59100 1.000 58.84000  ? 189 VAL A HG12 1 
ATOM   2947 H  HG13 . VAL A 1 189 ? -7.47700  -18.95700 -42.21200 1.000 58.84000  ? 189 VAL A HG13 1 
ATOM   2948 H  HG21 . VAL A 1 189 ? -4.86200  -17.33800 -42.31400 1.000 55.55000  ? 189 VAL A HG21 1 
ATOM   2949 H  HG22 . VAL A 1 189 ? -5.33700  -17.89200 -40.90300 1.000 55.55000  ? 189 VAL A HG22 1 
ATOM   2950 H  HG23 . VAL A 1 189 ? -3.91600  -18.30500 -41.48100 1.000 55.55000  ? 189 VAL A HG23 1 
ATOM   2951 N  N    . CYS A 1 190 ? -7.20400  -22.22000 -41.74000 1.000 51.54565  ? 190 CYS A N    1 
ATOM   2952 C  CA   . CYS A 1 190 ? -7.88400  -23.27500 -42.46700 1.000 50.28761  ? 190 CYS A CA   1 
ATOM   2953 C  C    . CYS A 1 190 ? -9.18900  -22.71700 -43.01700 1.000 56.78839  ? 190 CYS A C    1 
ATOM   2954 O  O    . CYS A 1 190 ? -9.84600  -21.89400 -42.37200 1.000 52.35628  ? 190 CYS A O    1 
ATOM   2955 C  CB   . CYS A 1 190 ? -8.15700  -24.47400 -41.57000 1.000 50.04021  ? 190 CYS A CB   1 
ATOM   2956 S  SG   . CYS A 1 190 ? -9.35100  -25.56600 -42.28700 1.000 47.32936  ? 190 CYS A SG   1 
ATOM   2957 H  H    . CYS A 1 190 ? -7.61400  -21.96800 -41.02700 1.000 61.86000  ? 190 CYS A H    1 
ATOM   2958 H  HA   . CYS A 1 190 ? -7.33600  -23.58400 -43.20500 1.000 60.35000  ? 190 CYS A HA   1 
ATOM   2959 H  HB2  . CYS A 1 190 ? -7.33200  -24.96800 -41.43700 1.000 60.05000  ? 190 CYS A HB2  1 
ATOM   2960 H  HB3  . CYS A 1 190 ? -8.49900  -24.16500 -40.71700 1.000 60.05000  ? 190 CYS A HB3  1 
ATOM   2961 N  N    . LYS A 1 191 ? -9.55400  -23.15500 -44.21900 1.000 54.60392  ? 191 LYS A N    1 
ATOM   2962 C  CA   . LYS A 1 191 ? -10.77800 -22.65100 -44.83500 1.000 64.36561  ? 191 LYS A CA   1 
ATOM   2963 C  C    . LYS A 1 191 ? -12.01200 -23.10300 -44.05800 1.000 63.68922  ? 191 LYS A C    1 
ATOM   2964 O  O    . LYS A 1 191 ? -12.96100 -22.32800 -43.88600 1.000 64.78672  ? 191 LYS A O    1 
ATOM   2965 C  CB   . LYS A 1 191 ? -10.84100 -23.10300 -46.29200 1.000 56.62258  ? 191 LYS A CB   1 
ATOM   2966 H  H    . LYS A 1 191 ? -9.12100  -23.73100 -44.68900 1.000 65.52000  ? 191 LYS A H    1 
ATOM   2967 H  HA   . LYS A 1 191 ? -10.76800 -21.68100 -44.82600 1.000 77.24000  ? 191 LYS A HA   1 
ATOM   2968 N  N    . THR A 1 192 ? -12.00900 -24.34900 -43.57500 1.000 66.78169  ? 192 THR A N    1 
ATOM   2969 C  CA   . THR A 1 192 ? -13.09200 -24.84400 -42.72900 1.000 58.68862  ? 192 THR A CA   1 
ATOM   2970 C  C    . THR A 1 192 ? -13.04200 -24.20800 -41.34100 1.000 65.33152  ? 192 THR A C    1 
ATOM   2971 O  O    . THR A 1 192 ? -14.02700 -23.62300 -40.87400 1.000 64.15506  ? 192 THR A O    1 
ATOM   2972 C  CB   . THR A 1 192 ? -12.99000 -26.37200 -42.60600 1.000 65.45258  ? 192 THR A CB   1 
ATOM   2973 O  OG1  . THR A 1 192 ? -13.27800 -27.00100 -43.86300 1.000 71.52173  ? 192 THR A OG1  1 
ATOM   2974 C  CG2  . THR A 1 192 ? -13.93000 -26.91500 -41.52100 1.000 61.06785  ? 192 THR A CG2  1 
ATOM   2975 H  H    . THR A 1 192 ? -11.39000 -24.92700 -43.72400 1.000 80.14000  ? 192 THR A H    1 
ATOM   2976 H  HA   . THR A 1 192 ? -13.93900 -24.61500 -43.14200 1.000 70.43000  ? 192 THR A HA   1 
ATOM   2977 H  HB   . THR A 1 192 ? -12.08200 -26.59700 -42.34600 1.000 78.54000  ? 192 THR A HB   1 
ATOM   2978 H  HG1  . THR A 1 192 ? -13.17600 -27.83200 -43.79800 1.000 85.82000  ? 192 THR A HG1  1 
ATOM   2979 H  HG21 . THR A 1 192 ? -14.00300 -27.87900 -41.59800 1.000 73.28000  ? 192 THR A HG21 1 
ATOM   2980 H  HG22 . THR A 1 192 ? -13.58500 -26.69400 -40.64200 1.000 73.28000  ? 192 THR A HG22 1 
ATOM   2981 H  HG23 . THR A 1 192 ? -14.81200 -26.52300 -41.62100 1.000 73.28000  ? 192 THR A HG23 1 
ATOM   2982 N  N    . CYS A 1 193 ? -11.89000 -24.30200 -40.67500 1.000 52.97740  ? 193 CYS A N    1 
ATOM   2983 C  CA   . CYS A 1 193 ? -11.79900 -24.11500 -39.23200 1.000 50.77188  ? 193 CYS A CA   1 
ATOM   2984 C  C    . CYS A 1 193 ? -11.46000 -22.69700 -38.79600 1.000 48.14788  ? 193 CYS A C    1 
ATOM   2985 O  O    . CYS A 1 193 ? -11.55600 -22.39700 -37.60200 1.000 53.65117  ? 193 CYS A O    1 
ATOM   2986 C  CB   . CYS A 1 193 ? -10.73600 -25.05600 -38.65400 1.000 46.80824  ? 193 CYS A CB   1 
ATOM   2987 S  SG   . CYS A 1 193 ? -10.98500 -26.79300 -39.01800 1.000 45.98709  ? 193 CYS A SG   1 
ATOM   2988 H  H    . CYS A 1 193 ? -11.13400 -24.47700 -41.04600 1.000 63.58000  ? 193 CYS A H    1 
ATOM   2989 H  HA   . CYS A 1 193 ? -12.66700 -24.33300 -38.85800 1.000 60.93000  ? 193 CYS A HA   1 
ATOM   2990 H  HB2  . CYS A 1 193 ? -9.87200  -24.80400 -39.01600 1.000 56.17000  ? 193 CYS A HB2  1 
ATOM   2991 H  HB3  . CYS A 1 193 ? -10.73200 -24.95900 -37.68900 1.000 56.17000  ? 193 CYS A HB3  1 
ATOM   2992 N  N    . GLY A 1 194 ? -11.03600 -21.82900 -39.69800 1.000 49.95599  ? 194 GLY A N    1 
ATOM   2993 C  CA   . GLY A 1 194 ? -10.76700 -20.46000 -39.34900 1.000 48.55319  ? 194 GLY A CA   1 
ATOM   2994 C  C    . GLY A 1 194 ? -9.31500  -20.19700 -39.02700 1.000 48.47160  ? 194 GLY A C    1 
ATOM   2995 O  O    . GLY A 1 194 ? -8.40600  -20.90900 -39.45500 1.000 50.77714  ? 194 GLY A O    1 
ATOM   2996 H  H    . GLY A 1 194 ? -10.89800 -22.01600 -40.52500 1.000 59.95000  ? 194 GLY A H    1 
ATOM   2997 H  HA2  . GLY A 1 194 ? -11.02000 -19.88800 -40.09100 1.000 58.26000  ? 194 GLY A HA2  1 
ATOM   2998 H  HA3  . GLY A 1 194 ? -11.29600 -20.22000 -38.57100 1.000 58.26000  ? 194 GLY A HA3  1 
ATOM   2999 N  N    . GLN A 1 195 ? -9.10100  -19.13500 -38.25800 1.000 54.74077  ? 195 GLN A N    1 
ATOM   3000 C  CA   . GLN A 1 195 ? -7.76800  -18.64500 -37.94500 1.000 52.16941  ? 195 GLN A CA   1 
ATOM   3001 C  C    . GLN A 1 195 ? -7.41700  -18.99300 -36.50600 1.000 53.29586  ? 195 GLN A C    1 
ATOM   3002 O  O    . GLN A 1 195 ? -8.26900  -18.93500 -35.61400 1.000 54.33283  ? 195 GLN A O    1 
ATOM   3003 C  CB   . GLN A 1 195 ? -7.67400  -17.12800 -38.13000 1.000 56.99104  ? 195 GLN A CB   1 
ATOM   3004 C  CG   . GLN A 1 195 ? -7.68800  -16.65100 -39.57100 1.000 64.01820  ? 195 GLN A CG   1 
ATOM   3005 C  CD   . GLN A 1 195 ? -7.16800  -15.22800 -39.71300 1.000 79.04632  ? 195 GLN A CD   1 
ATOM   3006 O  OE1  . GLN A 1 195 ? -6.79400  -14.58800 -38.72500 1.000 72.60081  ? 195 GLN A OE1  1 
ATOM   3007 N  NE2  . GLN A 1 195 ? -7.14800  -14.72400 -40.94600 1.000 75.23270  ? 195 GLN A NE2  1 
ATOM   3008 H  H    . GLN A 1 195 ? -9.73000  -18.67100 -37.89800 1.000 65.69000  ? 195 GLN A H    1 
ATOM   3009 H  HA   . GLN A 1 195 ? -7.12700  -19.06900 -38.53700 1.000 62.60000  ? 195 GLN A HA   1 
ATOM   3010 H  HB2  . GLN A 1 195 ? -8.42900  -16.71700 -37.68100 1.000 68.39000  ? 195 GLN A HB2  1 
ATOM   3011 H  HB3  . GLN A 1 195 ? -6.84400  -16.82100 -37.73200 1.000 68.39000  ? 195 GLN A HB3  1 
ATOM   3012 H  HG2  . GLN A 1 195 ? -7.12500  -17.23300 -40.10500 1.000 76.82000  ? 195 GLN A HG2  1 
ATOM   3013 H  HG3  . GLN A 1 195 ? -8.59900  -16.67400 -39.90500 1.000 76.82000  ? 195 GLN A HG3  1 
ATOM   3014 H  HE21 . GLN A 1 195 ? -7.42000  -15.19800 -41.60900 1.000 90.28000  ? 195 GLN A HE21 1 
ATOM   3015 H  HE22 . GLN A 1 195 ? -6.86200  -13.92300 -41.07900 1.000 90.28000  ? 195 GLN A HE22 1 
ATOM   3016 N  N    . GLN A 1 196 ? -6.15700  -19.33900 -36.28700 1.000 47.17671  ? 196 GLN A N    1 
ATOM   3017 C  CA   . GLN A 1 196 ? -5.63600  -19.57700 -34.94900 1.000 49.32697  ? 196 GLN A CA   1 
ATOM   3018 C  C    . GLN A 1 196 ? -4.27800  -18.90400 -34.85300 1.000 46.24239  ? 196 GLN A C    1 
ATOM   3019 O  O    . GLN A 1 196 ? -3.34600  -19.28300 -35.56700 1.000 46.16606  ? 196 GLN A O    1 
ATOM   3020 C  CB   . GLN A 1 196 ? -5.52700  -21.07400 -34.65300 1.000 58.42279  ? 196 GLN A CB   1 
ATOM   3021 C  CG   . GLN A 1 196 ? -5.06100  -21.36100 -33.24300 1.000 64.17612  ? 196 GLN A CG   1 
ATOM   3022 C  CD   . GLN A 1 196 ? -6.04200  -20.84800 -32.21100 1.000 69.29778  ? 196 GLN A CD   1 
ATOM   3023 O  OE1  . GLN A 1 196 ? -5.66100  -20.13800 -31.27900 1.000 66.89223  ? 196 GLN A OE1  1 
ATOM   3024 N  NE2  . GLN A 1 196 ? -7.31300  -21.20700 -32.36900 1.000 79.90695  ? 196 GLN A NE2  1 
ATOM   3025 H  H    . GLN A 1 196 ? -5.57300  -19.44500 -36.90900 1.000 56.61000  ? 196 GLN A H    1 
ATOM   3026 H  HA   . GLN A 1 196 ? -6.22800  -19.18600 -34.28700 1.000 59.19000  ? 196 GLN A HA   1 
ATOM   3027 H  HB2  . GLN A 1 196 ? -6.39800  -21.48400 -34.77000 1.000 70.10000  ? 196 GLN A HB2  1 
ATOM   3028 H  HB3  . GLN A 1 196 ? -4.88800  -21.47100 -35.26600 1.000 70.10000  ? 196 GLN A HB3  1 
ATOM   3029 H  HG2  . GLN A 1 196 ? -4.97000  -22.32000 -33.12500 1.000 77.01000  ? 196 GLN A HG2  1 
ATOM   3030 H  HG3  . GLN A 1 196 ? -4.20700  -20.92600 -33.09300 1.000 77.01000  ? 196 GLN A HG3  1 
ATOM   3031 H  HE21 . GLN A 1 196 ? -7.54000  -21.70500 -33.03200 1.000 95.89000  ? 196 GLN A HE21 1 
ATOM   3032 H  HE22 . GLN A 1 196 ? -7.90800  -20.94000 -31.80800 1.000 95.89000  ? 196 GLN A HE22 1 
ATOM   3033 N  N    . GLN A 1 197 ? -4.16800  -17.90100 -33.98500 1.000 45.55546  ? 197 GLN A N    1 
ATOM   3034 C  CA   . GLN A 1 197 ? -2.89500  -17.23700 -33.75700 1.000 43.54206  ? 197 GLN A CA   1 
ATOM   3035 C  C    . GLN A 1 197 ? -2.18900  -17.85800 -32.56500 1.000 46.89773  ? 197 GLN A C    1 
ATOM   3036 O  O    . GLN A 1 197 ? -2.81400  -18.16600 -31.54700 1.000 46.82404  ? 197 GLN A O    1 
ATOM   3037 C  CB   . GLN A 1 197 ? -3.08900  -15.74400 -33.50400 1.000 47.62676  ? 197 GLN A CB   1 
ATOM   3038 C  CG   . GLN A 1 197 ? -1.80800  -14.95400 -33.67100 1.000 50.97190  ? 197 GLN A CG   1 
ATOM   3039 C  CD   . GLN A 1 197 ? -1.97700  -13.48200 -33.37000 1.000 50.73766  ? 197 GLN A CD   1 
ATOM   3040 O  OE1  . GLN A 1 197 ? -2.27000  -12.68800 -34.26400 1.000 53.96173  ? 197 GLN A OE1  1 
ATOM   3041 N  NE2  . GLN A 1 197 ? -1.76900  -13.10400 -32.11000 1.000 51.31668  ? 197 GLN A NE2  1 
ATOM   3042 H  H    . GLN A 1 197 ? -4.81900  -17.58900 -33.51700 1.000 54.67000  ? 197 GLN A H    1 
ATOM   3043 H  HA   . GLN A 1 197 ? -2.34000  -17.34200 -34.54600 1.000 52.25000  ? 197 GLN A HA   1 
ATOM   3044 H  HB2  . GLN A 1 197 ? -3.74100  -15.39900 -34.13400 1.000 57.15000  ? 197 GLN A HB2  1 
ATOM   3045 H  HB3  . GLN A 1 197 ? -3.40600  -15.61600 -32.59600 1.000 57.15000  ? 197 GLN A HB3  1 
ATOM   3046 H  HG2  . GLN A 1 197 ? -1.13800  -15.30800 -33.06500 1.000 61.16000  ? 197 GLN A HG2  1 
ATOM   3047 H  HG3  . GLN A 1 197 ? -1.50300  -15.03800 -34.58800 1.000 61.16000  ? 197 GLN A HG3  1 
ATOM   3048 H  HE21 . GLN A 1 197 ? -1.55000  -13.68700 -31.51700 1.000 61.58000  ? 197 GLN A HE21 1 
ATOM   3049 H  HE22 . GLN A 1 197 ? -1.85300  -12.27700 -31.89000 1.000 61.58000  ? 197 GLN A HE22 1 
ATOM   3050 N  N    . THR A 1 198 ? -0.88300  -18.02700 -32.68500 1.000 43.86842  ? 198 THR A N    1 
ATOM   3051 C  CA   . THR A 1 198 ? -0.08300  -18.51300 -31.57400 1.000 42.86303  ? 198 THR A CA   1 
ATOM   3052 C  C    . THR A 1 198 ? 1.16000   -17.65200 -31.43100 1.000 38.50462  ? 198 THR A C    1 
ATOM   3053 O  O    . THR A 1 198 ? 1.68200   -17.09900 -32.40400 1.000 42.16558  ? 198 THR A O    1 
ATOM   3054 C  CB   . THR A 1 198 ? 0.32500   -19.96700 -31.75400 1.000 43.54733  ? 198 THR A CB   1 
ATOM   3055 O  OG1  . THR A 1 198 ? 1.05000   -20.09000 -32.97300 1.000 49.42172  ? 198 THR A OG1  1 
ATOM   3056 C  CG2  . THR A 1 198 ? -0.89700  -20.85200 -31.79400 1.000 46.45557  ? 198 THR A CG2  1 
ATOM   3057 H  H    . THR A 1 198 ? -0.43600  -17.86700 -33.40300 1.000 52.64000  ? 198 THR A H    1 
ATOM   3058 H  HA   . THR A 1 198 ? -0.60200  -18.44800 -30.75800 1.000 51.44000  ? 198 THR A HA   1 
ATOM   3059 H  HB   . THR A 1 198 ? 0.88000   -20.25600 -31.01200 1.000 52.26000  ? 198 THR A HB   1 
ATOM   3060 H  HG1  . THR A 1 198 ? 1.34300   -20.87300 -33.05500 1.000 59.30000  ? 198 THR A HG1  1 
ATOM   3061 H  HG21 . THR A 1 198 ? -0.66000  -21.72800 -32.13700 1.000 55.75000  ? 198 THR A HG21 1 
ATOM   3062 H  HG22 . THR A 1 198 ? -1.26400  -20.95200 -30.90200 1.000 55.75000  ? 198 THR A HG22 1 
ATOM   3063 H  HG23 . THR A 1 198 ? -1.57200  -20.46000 -32.37000 1.000 55.75000  ? 198 THR A HG23 1 
ATOM   3064 N  N    . THR A 1 199 ? 1.60700   -17.52300 -30.19400 1.000 37.67820  ? 199 THR A N    1 
ATOM   3065 C  CA   . THR A 1 199 ? 2.76500   -16.71900 -29.85400 1.000 35.71481  ? 199 THR A CA   1 
ATOM   3066 C  C    . THR A 1 199 ? 3.79500   -17.66000 -29.25400 1.000 38.05456  ? 199 THR A C    1 
ATOM   3067 O  O    . THR A 1 199 ? 3.48000   -18.41800 -28.33400 1.000 38.81255  ? 199 THR A O    1 
ATOM   3068 C  CB   . THR A 1 199 ? 2.39900   -15.60900 -28.87400 1.000 41.21284  ? 199 THR A CB   1 
ATOM   3069 O  OG1  . THR A 1 199 ? 1.58700   -14.63600 -29.54200 1.000 43.51048  ? 199 THR A OG1  1 
ATOM   3070 C  CG2  . THR A 1 199 ? 3.64900   -14.92200 -28.35800 1.000 39.58106  ? 199 THR A CG2  1 
ATOM   3071 H  H    . THR A 1 199 ? 1.24500   -17.90400 -29.51400 1.000 45.21000  ? 199 THR A H    1 
ATOM   3072 H  HA   . THR A 1 199 ? 3.13800   -16.28900 -30.64000 1.000 42.86000  ? 199 THR A HA   1 
ATOM   3073 H  HB   . THR A 1 199 ? 1.91700   -15.98900 -28.12200 1.000 49.45000  ? 199 THR A HB   1 
ATOM   3074 H  HG1  . THR A 1 199 ? 1.34800   -14.04100 -29.00000 1.000 52.21000  ? 199 THR A HG1  1 
ATOM   3075 H  HG21 . THR A 1 199 ? 3.41200   -14.09700 -27.90700 1.000 47.50000  ? 199 THR A HG21 1 
ATOM   3076 H  HG22 . THR A 1 199 ? 4.11200   -15.50100 -27.73200 1.000 47.50000  ? 199 THR A HG22 1 
ATOM   3077 H  HG23 . THR A 1 199 ? 4.24400   -14.71800 -29.09600 1.000 47.50000  ? 199 THR A HG23 1 
ATOM   3078 N  N    . LEU A 1 200 ? 5.00500   -17.62700 -29.79300 1.000 34.83049  ? 200 LEU A N    1 
ATOM   3079 C  CA   . LEU A 1 200 ? 6.11300   -18.44600 -29.33400 1.000 34.03566  ? 200 LEU A CA   1 
ATOM   3080 C  C    . LEU A 1 200 ? 7.20800   -17.53900 -28.79700 1.000 37.52818  ? 200 LEU A C    1 
ATOM   3081 O  O    . LEU A 1 200 ? 7.40000   -16.42200 -29.27700 1.000 35.98063  ? 200 LEU A O    1 
ATOM   3082 C  CB   . LEU A 1 200 ? 6.64800   -19.32600 -30.45800 1.000 34.07777  ? 200 LEU A CB   1 
ATOM   3083 C  CG   . LEU A 1 200 ? 5.62000   -20.31100 -31.00300 1.000 39.86531  ? 200 LEU A CG   1 
ATOM   3084 C  CD1  . LEU A 1 200 ? 6.17300   -20.98900 -32.21400 1.000 40.37589  ? 200 LEU A CD1  1 
ATOM   3085 C  CD2  . LEU A 1 200 ? 5.23400   -21.34700 -29.96900 1.000 43.51311  ? 200 LEU A CD2  1 
ATOM   3086 H  H    . LEU A 1 200 ? 5.21600   -17.11700 -30.45200 1.000 41.80000  ? 200 LEU A H    1 
ATOM   3087 H  HA   . LEU A 1 200 ? 5.82800   -19.03400 -28.61700 1.000 40.84000  ? 200 LEU A HA   1 
ATOM   3088 H  HB2  . LEU A 1 200 ? 6.93300   -18.75700 -31.19000 1.000 40.89000  ? 200 LEU A HB2  1 
ATOM   3089 H  HB3  . LEU A 1 200 ? 7.40100   -19.83700 -30.12300 1.000 40.89000  ? 200 LEU A HB3  1 
ATOM   3090 H  HG   . LEU A 1 200 ? 4.81700   -19.82100 -31.23800 1.000 47.84000  ? 200 LEU A HG   1 
ATOM   3091 H  HD11 . LEU A 1 200 ? 5.51300   -21.61200 -32.55600 1.000 48.45000  ? 200 LEU A HD11 1 
ATOM   3092 H  HD12 . LEU A 1 200 ? 6.37700   -20.32000 -32.88600 1.000 48.45000  ? 200 LEU A HD12 1 
ATOM   3093 H  HD13 . LEU A 1 200 ? 6.98100   -21.46700 -31.96700 1.000 48.45000  ? 200 LEU A HD13 1 
ATOM   3094 H  HD21 . LEU A 1 200 ? 4.63100   -21.98900 -30.37500 1.000 52.22000  ? 200 LEU A HD21 1 
ATOM   3095 H  HD22 . LEU A 1 200 ? 6.03600   -21.79700 -29.65900 1.000 52.22000  ? 200 LEU A HD22 1 
ATOM   3096 H  HD23 . LEU A 1 200 ? 4.79500   -20.90400 -29.22600 1.000 52.22000  ? 200 LEU A HD23 1 
ATOM   3097 N  N    . LYS A 1 201 ? 7.92300   -18.02900 -27.78600 1.000 33.16450  ? 201 LYS A N    1 
ATOM   3098 C  CA   . LYS A 1 201 ? 8.93400   -17.24400 -27.10300 1.000 34.13567  ? 201 LYS A CA   1 
ATOM   3099 C  C    . LYS A 1 201 ? 10.20700  -18.05800 -26.97100 1.000 34.09356  ? 201 LYS A C    1 
ATOM   3100 O  O    . LYS A 1 201 ? 10.17600  -19.29300 -26.93100 1.000 36.24119  ? 201 LYS A O    1 
ATOM   3101 C  CB   . LYS A 1 201 ? 8.44200   -16.79200 -25.71600 1.000 38.72570  ? 201 LYS A CB   1 
ATOM   3102 C  CG   . LYS A 1 201 ? 7.14500   -15.99500 -25.77100 1.000 44.58166  ? 201 LYS A CG   1 
ATOM   3103 C  CD   . LYS A 1 201 ? 6.77600   -15.38500 -24.42500 1.000 67.74760  ? 201 LYS A CD   1 
ATOM   3104 C  CE   . LYS A 1 201 ? 5.99200   -14.08400 -24.59000 1.000 85.13389  ? 201 LYS A CE   1 
ATOM   3105 N  NZ   . LYS A 1 201 ? 5.95600   -13.29200 -23.32300 1.000 97.21692  ? 201 LYS A NZ   1 
ATOM   3106 H  H    . LYS A 1 201 ? 7.83600   -18.82700 -27.47800 1.000 39.79000  ? 201 LYS A H    1 
ATOM   3107 H  HA   . LYS A 1 201 ? 9.14300   -16.45100 -27.62000 1.000 40.96000  ? 201 LYS A HA   1 
ATOM   3108 H  HB2  . LYS A 1 201 ? 8.28800   -17.57700 -25.16700 1.000 46.47000  ? 201 LYS A HB2  1 
ATOM   3109 H  HB3  . LYS A 1 201 ? 9.12100   -16.23100 -25.31000 1.000 46.47000  ? 201 LYS A HB3  1 
ATOM   3110 H  HG2  . LYS A 1 201 ? 7.24300   -15.27300 -26.41100 1.000 53.50000  ? 201 LYS A HG2  1 
ATOM   3111 H  HG3  . LYS A 1 201 ? 6.42300   -16.58300 -26.04200 1.000 53.50000  ? 201 LYS A HG3  1 
ATOM   3112 H  HD2  . LYS A 1 201 ? 6.22600   -16.01100 -23.92900 1.000 81.30000  ? 201 LYS A HD2  1 
ATOM   3113 H  HD3  . LYS A 1 201 ? 7.58700   -15.19000 -23.92800 1.000 81.30000  ? 201 LYS A HD3  1 
ATOM   3114 H  HE2  . LYS A 1 201 ? 6.41300   -13.54200 -25.27500 1.000 102.16000 ? 201 LYS A HE2  1 
ATOM   3115 H  HE3  . LYS A 1 201 ? 5.08000   -14.29100 -24.84500 1.000 102.16000 ? 201 LYS A HE3  1 
ATOM   3116 H  HZ1  . LYS A 1 201 ? 5.49500   -12.54100 -23.44600 1.000 116.66000 ? 201 LYS A HZ1  1 
ATOM   3117 H  HZ2  . LYS A 1 201 ? 5.56800   -13.76700 -22.67800 1.000 116.66000 ? 201 LYS A HZ2  1 
ATOM   3118 H  HZ3  . LYS A 1 201 ? 6.78400   -13.08400 -23.07000 1.000 116.66000 ? 201 LYS A HZ3  1 
ATOM   3119 N  N    . GLY A 1 202 ? 11.32500  -17.35000 -26.91400 1.000 34.22252  ? 202 GLY A N    1 
ATOM   3120 C  CA   . GLY A 1 202 ? 12.58300  -18.00600 -26.59900 1.000 36.50701  ? 202 GLY A CA   1 
ATOM   3121 C  C    . GLY A 1 202 ? 12.99800  -18.95300 -27.70200 1.000 35.23054  ? 202 GLY A C    1 
ATOM   3122 O  O    . GLY A 1 202 ? 12.94100  -18.60900 -28.88900 1.000 32.80130  ? 202 GLY A O    1 
ATOM   3123 H  H    . GLY A 1 202 ? 11.38300  -16.50300 -27.05200 1.000 41.07000  ? 202 GLY A H    1 
ATOM   3124 H  HA2  . GLY A 1 202 ? 13.27900  -17.34000 -26.48400 1.000 43.81000  ? 202 GLY A HA2  1 
ATOM   3125 H  HA3  . GLY A 1 202 ? 12.49100  -18.51100 -25.77600 1.000 43.81000  ? 202 GLY A HA3  1 
ATOM   3126 N  N    . VAL A 1 203 ? 13.40100  -20.16800 -27.31700 1.000 32.85657  ? 203 VAL A N    1 
ATOM   3127 C  CA   . VAL A 1 203 ? 13.92200  -21.10600 -28.31600 1.000 33.45138  ? 203 VAL A CA   1 
ATOM   3128 C  C    . VAL A 1 203 ? 12.87400  -21.43900 -29.37100 1.000 32.34598  ? 203 VAL A C    1 
ATOM   3129 O  O    . VAL A 1 203 ? 13.20400  -21.55700 -30.55600 1.000 31.41956  ? 203 VAL A O    1 
ATOM   3130 C  CB   . VAL A 1 203 ? 14.48600  -22.36000 -27.62600 1.000 36.99654  ? 203 VAL A CB   1 
ATOM   3131 C  CG1  . VAL A 1 203 ? 13.40200  -23.12300 -26.88300 1.000 46.69770  ? 203 VAL A CG1  1 
ATOM   3132 C  CG2  . VAL A 1 203 ? 15.11000  -23.27400 -28.64900 1.000 31.65906  ? 203 VAL A CG2  1 
ATOM   3133 H  H    . VAL A 1 203 ? 13.38300  -20.46500 -26.51000 1.000 39.43000  ? 203 VAL A H    1 
ATOM   3134 H  HA   . VAL A 1 203 ? 14.65400  -20.67300 -28.78300 1.000 40.14000  ? 203 VAL A HA   1 
ATOM   3135 H  HB   . VAL A 1 203 ? 15.15500  -22.07200 -26.98400 1.000 44.40000  ? 203 VAL A HB   1 
ATOM   3136 H  HG11 . VAL A 1 203 ? 13.79900  -23.89400 -26.44900 1.000 56.03000  ? 203 VAL A HG11 1 
ATOM   3137 H  HG12 . VAL A 1 203 ? 13.00300  -22.53900 -26.21800 1.000 56.03000  ? 203 VAL A HG12 1 
ATOM   3138 H  HG13 . VAL A 1 203 ? 12.72700  -23.41100 -27.51700 1.000 56.03000  ? 203 VAL A HG13 1 
ATOM   3139 H  HG21 . VAL A 1 203 ? 15.51200  -24.03100 -28.19300 1.000 37.99000  ? 203 VAL A HG21 1 
ATOM   3140 H  HG22 . VAL A 1 203 ? 14.42200  -23.58200 -29.25900 1.000 37.99000  ? 203 VAL A HG22 1 
ATOM   3141 H  HG23 . VAL A 1 203 ? 15.79000  -22.78400 -29.13800 1.000 37.99000  ? 203 VAL A HG23 1 
ATOM   3142 N  N    . GLU A 1 204 ? 11.60500  -21.60400 -28.97700 1.000 32.83552  ? 204 GLU A N    1 
ATOM   3143 C  CA   . GLU A 1 204 ? 10.59200  -21.89200 -29.98400 1.000 34.13304  ? 204 GLU A CA   1 
ATOM   3144 C  C    . GLU A 1 204 ? 10.35100  -20.71400 -30.92300 1.000 31.40377  ? 204 GLU A C    1 
ATOM   3145 O  O    . GLU A 1 204 ? 9.76200   -20.89400 -32.00000 1.000 33.47507  ? 204 GLU A O    1 
ATOM   3146 C  CB   . GLU A 1 204 ? 9.23500   -22.31100 -29.39200 1.000 39.11522  ? 204 GLU A CB   1 
ATOM   3147 C  CG   . GLU A 1 204 ? 9.15100   -23.68100 -28.74000 1.000 47.01880  ? 204 GLU A CG   1 
ATOM   3148 C  CD   . GLU A 1 204 ? 9.70200   -23.72900 -27.33500 1.000 59.81507  ? 204 GLU A CD   1 
ATOM   3149 O  OE1  . GLU A 1 204 ? 10.10700  -22.66700 -26.80200 1.000 53.52747  ? 204 GLU A OE1  1 
ATOM   3150 O  OE2  . GLU A 1 204 ? 9.69300   -24.84400 -26.75500 1.000 51.72462  ? 204 GLU A OE2  1 
ATOM   3151 H  H    . GLU A 1 204 ? 11.32200  -21.55500 -28.16600 1.000 39.40000  ? 204 GLU A H    1 
ATOM   3152 H  HA   . GLU A 1 204 ? 10.93100  -22.65500 -30.47700 1.000 40.96000  ? 204 GLU A HA   1 
ATOM   3153 H  HB2  . GLU A 1 204 ? 8.99300   -21.66100 -28.71400 1.000 46.94000  ? 204 GLU A HB2  1 
ATOM   3154 H  HB3  . GLU A 1 204 ? 8.58200   -22.30100 -30.10900 1.000 46.94000  ? 204 GLU A HB3  1 
ATOM   3155 H  HG2  . GLU A 1 204 ? 8.22000   -23.95000 -28.70100 1.000 56.42000  ? 204 GLU A HG2  1 
ATOM   3156 H  HG3  . GLU A 1 204 ? 9.65700   -24.31100 -29.27600 1.000 56.42000  ? 204 GLU A HG3  1 
ATOM   3157 N  N    . ALA A 1 205 ? 10.77900  -19.50900 -30.54600 1.000 27.78491  ? 205 ALA A N    1 
ATOM   3158 C  CA   . ALA A 1 205 ? 10.59300  -18.34800 -31.41300 1.000 29.98781  ? 205 ALA A CA   1 
ATOM   3159 C  C    . ALA A 1 205 ? 11.59200  -18.30000 -32.56300 1.000 29.98517  ? 205 ALA A C    1 
ATOM   3160 O  O    . ALA A 1 205 ? 11.33900  -17.59500 -33.54800 1.000 31.17216  ? 205 ALA A O    1 
ATOM   3161 C  CB   . ALA A 1 205 ? 10.69600  -17.04300 -30.61800 1.000 32.81972  ? 205 ALA A CB   1 
ATOM   3162 H  H    . ALA A 1 205 ? 11.17400  -19.34000 -29.80100 1.000 33.34000  ? 205 ALA A H    1 
ATOM   3163 H  HA   . ALA A 1 205 ? 9.69800   -18.40200 -31.78400 1.000 35.98000  ? 205 ALA A HA   1 
ATOM   3164 H  HB1  . ALA A 1 205 ? 10.55900  -16.29500 -31.22000 1.000 39.38000  ? 205 ALA A HB1  1 
ATOM   3165 H  HB2  . ALA A 1 205 ? 10.01500  -17.04100 -29.92700 1.000 39.38000  ? 205 ALA A HB2  1 
ATOM   3166 H  HB3  . ALA A 1 205 ? 11.57600  -16.98800 -30.21600 1.000 39.38000  ? 205 ALA A HB3  1 
ATOM   3167 N  N    . VAL A 1 206 ? 12.70700  -19.02800 -32.48400 1.000 28.87188  ? 206 VAL A N    1 
ATOM   3168 C  CA   . VAL A 1 206 ? 13.74600  -18.92900 -33.50100 1.000 30.92476  ? 206 VAL A CA   1 
ATOM   3169 C  C    . VAL A 1 206 ? 13.95100  -20.21300 -34.28100 1.000 31.41429  ? 206 VAL A C    1 
ATOM   3170 O  O    . VAL A 1 206 ? 14.77600  -20.23500 -35.19500 1.000 31.69327  ? 206 VAL A O    1 
ATOM   3171 C  CB   . VAL A 1 206 ? 15.09100  -18.45800 -32.90600 1.000 30.82738  ? 206 VAL A CB   1 
ATOM   3172 C  CG1  . VAL A 1 206 ? 14.93300  -17.10200 -32.24600 1.000 30.97477  ? 206 VAL A CG1  1 
ATOM   3173 C  CG2  . VAL A 1 206 ? 15.65800  -19.46400 -31.94400 1.000 32.61707  ? 206 VAL A CG2  1 
ATOM   3174 H  H    . VAL A 1 206 ? 12.88100  -19.58400 -31.85100 1.000 34.64000  ? 206 VAL A H    1 
ATOM   3175 H  HA   . VAL A 1 206 ? 13.45400  -18.25800 -34.13800 1.000 37.11000  ? 206 VAL A HA   1 
ATOM   3176 H  HB   . VAL A 1 206 ? 15.72900  -18.37200 -33.63100 1.000 36.99000  ? 206 VAL A HB   1 
ATOM   3177 H  HG11 . VAL A 1 206 ? 15.79900  -16.80500 -31.92400 1.000 37.17000  ? 206 VAL A HG11 1 
ATOM   3178 H  HG12 . VAL A 1 206 ? 14.59000  -16.47100 -32.89900 1.000 37.17000  ? 206 VAL A HG12 1 
ATOM   3179 H  HG13 . VAL A 1 206 ? 14.31300  -17.18100 -31.50500 1.000 37.17000  ? 206 VAL A HG13 1 
ATOM   3180 H  HG21 . VAL A 1 206 ? 16.43100  -19.07800 -31.50300 1.000 39.14000  ? 206 VAL A HG21 1 
ATOM   3181 H  HG22 . VAL A 1 206 ? 14.98100  -19.69000 -31.28700 1.000 39.14000  ? 206 VAL A HG22 1 
ATOM   3182 H  HG23 . VAL A 1 206 ? 15.92000  -20.25800 -32.43500 1.000 39.14000  ? 206 VAL A HG23 1 
ATOM   3183 N  N    . MET A 1 207 ? 13.21400  -21.27100 -33.97800 1.000 29.32983  ? 207 MET A N    1 
ATOM   3184 C  CA   . MET A 1 207 ? 13.39900  -22.57200 -34.61000 1.000 30.86686  ? 207 MET A CA   1 
ATOM   3185 C  C    . MET A 1 207 ? 12.10500  -22.94600 -35.32300 1.000 31.35902  ? 207 MET A C    1 
ATOM   3186 O  O    . MET A 1 207 ? 11.01000  -22.73100 -34.79800 1.000 33.64088  ? 207 MET A O    1 
ATOM   3187 C  CB   . MET A 1 207 ? 13.76700  -23.59700 -33.53800 1.000 30.90107  ? 207 MET A CB   1 
ATOM   3188 C  CG   . MET A 1 207 ? 15.24600  -23.50200 -33.10900 1.000 32.89868  ? 207 MET A CG   1 
ATOM   3189 S  SD   . MET A 1 207 ? 15.74900  -24.85900 -32.04000 1.000 36.72546  ? 207 MET A SD   1 
ATOM   3190 C  CE   . MET A 1 207 ? 16.28400  -25.99400 -33.31400 1.000 31.78013  ? 207 MET A CE   1 
ATOM   3191 H  H    . MET A 1 207 ? 12.58300  -21.26200 -33.39300 1.000 35.20000  ? 207 MET A H    1 
ATOM   3192 H  HA   . MET A 1 207 ? 14.11100  -22.56100 -35.26900 1.000 37.04000  ? 207 MET A HA   1 
ATOM   3193 H  HB2  . MET A 1 207 ? 13.21700  -23.44500 -32.75400 1.000 37.08000  ? 207 MET A HB2  1 
ATOM   3194 H  HB3  . MET A 1 207 ? 13.61200  -24.48900 -33.88500 1.000 37.08000  ? 207 MET A HB3  1 
ATOM   3195 H  HG2  . MET A 1 207 ? 15.80600  -23.52000 -33.90100 1.000 39.48000  ? 207 MET A HG2  1 
ATOM   3196 H  HG3  . MET A 1 207 ? 15.38200  -22.67200 -32.62500 1.000 39.48000  ? 207 MET A HG3  1 
ATOM   3197 H  HE1  . MET A 1 207 ? 16.58300  -26.81800 -32.89900 1.000 38.14000  ? 207 MET A HE1  1 
ATOM   3198 H  HE2  . MET A 1 207 ? 15.54000  -26.17500 -33.90900 1.000 38.14000  ? 207 MET A HE2  1 
ATOM   3199 H  HE3  . MET A 1 207 ? 17.01300  -25.59000 -33.81100 1.000 38.14000  ? 207 MET A HE3  1 
ATOM   3200 N  N    . TYR A 1 208 ? 12.21600  -23.46700 -36.53800 1.000 28.38235  ? 208 TYR A N    1 
ATOM   3201 C  CA   . TYR A 1 208 ? 11.06600  -24.01700 -37.23700 1.000 32.57759  ? 208 TYR A CA   1 
ATOM   3202 C  C    . TYR A 1 208 ? 11.51000  -25.24900 -38.01800 1.000 31.98015  ? 208 TYR A C    1 
ATOM   3203 O  O    . TYR A 1 208 ? 12.56100  -25.24100 -38.67100 1.000 30.25363  ? 208 TYR A O    1 
ATOM   3204 C  CB   . TYR A 1 208 ? 10.39500  -23.03000 -38.21100 1.000 31.81434  ? 208 TYR A CB   1 
ATOM   3205 C  CG   . TYR A 1 208 ? 9.17400   -23.66500 -38.86000 1.000 33.12239  ? 208 TYR A CG   1 
ATOM   3206 C  CD1  . TYR A 1 208 ? 8.00500   -23.85400 -38.13200 1.000 34.69890  ? 208 TYR A CD1  1 
ATOM   3207 C  CD2  . TYR A 1 208 ? 9.20500   -24.11700 -40.16700 1.000 33.84616  ? 208 TYR A CD2  1 
ATOM   3208 C  CE1  . TYR A 1 208 ? 6.89200   -24.45700 -38.69500 1.000 35.84377  ? 208 TYR A CE1  1 
ATOM   3209 C  CE2  . TYR A 1 208 ? 8.08500   -24.72200 -40.74300 1.000 32.96448  ? 208 TYR A CE2  1 
ATOM   3210 C  CZ   . TYR A 1 208 ? 6.93900   -24.88800 -40.00000 1.000 37.30184  ? 208 TYR A CZ   1 
ATOM   3211 O  OH   . TYR A 1 208 ? 5.83400   -25.49800 -40.55400 1.000 36.70177  ? 208 TYR A OH   1 
ATOM   3212 H  H    . TYR A 1 208 ? 12.95300  -23.51300 -36.98000 1.000 34.06000  ? 208 TYR A H    1 
ATOM   3213 H  HA   . TYR A 1 208 ? 10.40200  -24.25900 -36.57300 1.000 39.09000  ? 208 TYR A HA   1 
ATOM   3214 H  HB2  . TYR A 1 208 ? 10.11200  -22.23900 -37.72600 1.000 38.18000  ? 208 TYR A HB2  1 
ATOM   3215 H  HB3  . TYR A 1 208 ? 11.02400  -22.78500 -38.90700 1.000 38.18000  ? 208 TYR A HB3  1 
ATOM   3216 H  HD1  . TYR A 1 208 ? 7.96900   -23.56900 -37.24800 1.000 41.64000  ? 208 TYR A HD1  1 
ATOM   3217 H  HD2  . TYR A 1 208 ? 9.98100   -24.01700 -40.66900 1.000 40.62000  ? 208 TYR A HD2  1 
ATOM   3218 H  HE1  . TYR A 1 208 ? 6.11800   -24.57000 -38.19300 1.000 43.01000  ? 208 TYR A HE1  1 
ATOM   3219 H  HE2  . TYR A 1 208 ? 8.11400   -25.01200 -41.62600 1.000 39.56000  ? 208 TYR A HE2  1 
ATOM   3220 H  HH   . TYR A 1 208 ? 5.24200   -25.60800 -39.96800 1.000 44.04000  ? 208 TYR A HH   1 
ATOM   3221 N  N    . MET A 1 209 ? 10.70100  -26.30100 -37.95500 1.000 30.13782  ? 209 MET A N    1 
ATOM   3222 C  CA   . MET A 1 209 ? 10.98500  -27.57900 -38.63900 1.000 29.64040  ? 209 MET A CA   1 
ATOM   3223 C  C    . MET A 1 209 ? 9.91500   -27.81000 -39.69300 1.000 32.74866  ? 209 MET A C    1 
ATOM   3224 O  O    . MET A 1 209 ? 8.74900   -27.93800 -39.31100 1.000 32.05648  ? 209 MET A O    1 
ATOM   3225 C  CB   . MET A 1 209 ? 10.97400  -28.74400 -37.64700 1.000 32.69603  ? 209 MET A CB   1 
ATOM   3226 C  CG   . MET A 1 209 ? 10.90100  -30.12700 -38.26000 1.000 41.62868  ? 209 MET A CG   1 
ATOM   3227 S  SD   . MET A 1 209 ? 12.20900  -30.47500 -39.44000 1.000 39.72845  ? 209 MET A SD   1 
ATOM   3228 C  CE   . MET A 1 209 ? 13.65800  -30.18200 -38.43300 1.000 42.58142  ? 209 MET A CE   1 
ATOM   3229 H  H    . MET A 1 209 ? 9.91000   -26.30400 -37.49800 1.000 36.16000  ? 209 MET A H    1 
ATOM   3230 H  HA   . MET A 1 209 ? 11.86000  -27.52900 -39.07700 1.000 35.57000  ? 209 MET A HA   1 
ATOM   3231 H  HB2  . MET A 1 209 ? 11.77800  -28.68600 -37.09800 1.000 39.24000  ? 209 MET A HB2  1 
ATOM   3232 H  HB3  . MET A 1 209 ? 10.20800  -28.62800 -37.05200 1.000 39.24000  ? 209 MET A HB3  1 
ATOM   3233 H  HG2  . MET A 1 209 ? 10.95400  -30.79000 -37.53900 1.000 49.96000  ? 209 MET A HG2  1 
ATOM   3234 H  HG3  . MET A 1 209 ? 10.03500  -30.24400 -38.70300 1.000 49.96000  ? 209 MET A HG3  1 
ATOM   3235 H  HE1  . MET A 1 209 ? 14.45200  -30.32300 -38.96300 1.000 51.10000  ? 209 MET A HE1  1 
ATOM   3236 H  HE2  . MET A 1 209 ? 13.64700  -29.27400 -38.10900 1.000 51.10000  ? 209 MET A HE2  1 
ATOM   3237 H  HE3  . MET A 1 209 ? 13.65500  -30.78900 -37.68400 1.000 51.10000  ? 209 MET A HE3  1 
ATOM   3238 N  N    . GLY A 1 210 ? 10.28900  -27.80500 -40.96700 1.000 31.65906  ? 210 GLY A N    1 
ATOM   3239 C  CA   . GLY A 1 210 ? 9.37300   -28.18400 -42.01600 1.000 33.20398  ? 210 GLY A CA   1 
ATOM   3240 C  C    . GLY A 1 210 ? 9.70000   -27.52900 -43.34000 1.000 32.10911  ? 210 GLY A C    1 
ATOM   3241 O  O    . GLY A 1 210 ? 9.34000   -28.05400 -44.39600 1.000 34.53046  ? 210 GLY A O    1 
ATOM   3242 H  H    . GLY A 1 210 ? 11.08300  -27.61500 -41.23600 1.000 37.99000  ? 210 GLY A H    1 
ATOM   3243 H  HA2  . GLY A 1 210 ? 9.40600   -29.14600 -42.13600 1.000 39.84000  ? 210 GLY A HA2  1 
ATOM   3244 H  HA3  . GLY A 1 210 ? 8.47300   -27.92800 -41.76200 1.000 39.84000  ? 210 GLY A HA3  1 
ATOM   3245 N  N    . THR A 1 211 ? 10.36400  -26.37700 -43.30200 1.000 28.38235  ? 211 THR A N    1 
ATOM   3246 C  CA   . THR A 1 211 ? 10.88300  -25.77600 -44.52200 1.000 32.09069  ? 211 THR A CA   1 
ATOM   3247 C  C    . THR A 1 211 ? 12.18100  -25.04800 -44.22200 1.000 29.57723  ? 211 THR A C    1 
ATOM   3248 O  O    . THR A 1 211 ? 12.40700  -24.56500 -43.10600 1.000 30.54840  ? 211 THR A O    1 
ATOM   3249 C  CB   . THR A 1 211 ? 9.90300   -24.79700 -45.17300 1.000 33.74352  ? 211 THR A CB   1 
ATOM   3250 O  OG1  . THR A 1 211 ? 10.46900  -24.26500 -46.39200 1.000 34.67784  ? 211 THR A OG1  1 
ATOM   3251 C  CG2  . THR A 1 211 ? 9.59900   -23.64000 -44.27900 1.000 34.50940  ? 211 THR A CG2  1 
ATOM   3252 H  H    . THR A 1 211 ? 10.52400  -25.92800 -42.58600 1.000 34.06000  ? 211 THR A H    1 
ATOM   3253 H  HA   . THR A 1 211 ? 11.05700  -26.49400 -45.15000 1.000 38.51000  ? 211 THR A HA   1 
ATOM   3254 H  HB   . THR A 1 211 ? 9.08200   -25.28000 -45.35700 1.000 40.49000  ? 211 THR A HB   1 
ATOM   3255 H  HG1  . THR A 1 211 ? 10.65800  -24.89100 -46.91900 1.000 41.61000  ? 211 THR A HG1  1 
ATOM   3256 H  HG21 . THR A 1 211 ? 8.83500   -23.14800 -44.62000 1.000 41.41000  ? 211 THR A HG21 1 
ATOM   3257 H  HG22 . THR A 1 211 ? 9.39600   -23.95600 -43.38500 1.000 41.41000  ? 211 THR A HG22 1 
ATOM   3258 H  HG23 . THR A 1 211 ? 10.36300  -23.04400 -44.23600 1.000 41.41000  ? 211 THR A HG23 1 
ATOM   3259 N  N    . LEU A 1 212 ? 13.02400  -24.96200 -45.25000 1.000 31.07215  ? 212 LEU A N    1 
ATOM   3260 C  CA   . LEU A 1 212 ? 14.28200  -24.25000 -45.15200 1.000 30.45102  ? 212 LEU A CA   1 
ATOM   3261 C  C    . LEU A 1 212 ? 14.15900  -22.78600 -45.52400 1.000 31.76960  ? 212 LEU A C    1 
ATOM   3262 O  O    . LEU A 1 212 ? 15.07700  -22.01100 -45.23200 1.000 31.54326  ? 212 LEU A O    1 
ATOM   3263 C  CB   . LEU A 1 212 ? 15.32700  -24.87000 -46.08200 1.000 29.40879  ? 212 LEU A CB   1 
ATOM   3264 C  CG   . LEU A 1 212 ? 15.74600  -26.32300 -45.87900 1.000 28.56132  ? 212 LEU A CG   1 
ATOM   3265 C  CD1  . LEU A 1 212 ? 16.80200  -26.69700 -46.89700 1.000 30.22994  ? 212 LEU A CD1  1 
ATOM   3266 C  CD2  . LEU A 1 212 ? 16.26700  -26.51000 -44.46600 1.000 30.62209  ? 212 LEU A CD2  1 
ATOM   3267 H  H    . LEU A 1 212 ? 12.88400  -25.31500 -46.02100 1.000 37.29000  ? 212 LEU A H    1 
ATOM   3268 H  HA   . LEU A 1 212 ? 14.59400  -24.32400 -44.23700 1.000 36.54000  ? 212 LEU A HA   1 
ATOM   3269 H  HB2  . LEU A 1 212 ? 14.98000  -24.81100 -46.98600 1.000 35.29000  ? 212 LEU A HB2  1 
ATOM   3270 H  HB3  . LEU A 1 212 ? 16.13500  -24.34000 -46.00200 1.000 35.29000  ? 212 LEU A HB3  1 
ATOM   3271 H  HG   . LEU A 1 212 ? 14.98500  -26.91200 -46.00200 1.000 34.28000  ? 212 LEU A HG   1 
ATOM   3272 H  HD11 . LEU A 1 212 ? 17.11600  -27.59500 -46.71100 1.000 36.27000  ? 212 LEU A HD11 1 
ATOM   3273 H  HD12 . LEU A 1 212 ? 16.41300  -26.65900 -47.78400 1.000 36.27000  ? 212 LEU A HD12 1 
ATOM   3274 H  HD13 . LEU A 1 212 ? 17.53900  -26.06900 -46.83200 1.000 36.27000  ? 212 LEU A HD13 1 
ATOM   3275 H  HD21 . LEU A 1 212 ? 16.65600  -27.39500 -44.38700 1.000 36.75000  ? 212 LEU A HD21 1 
ATOM   3276 H  HD22 . LEU A 1 212 ? 16.94100  -25.83600 -44.28600 1.000 36.75000  ? 212 LEU A HD22 1 
ATOM   3277 H  HD23 . LEU A 1 212 ? 15.53000  -26.41600 -43.84200 1.000 36.75000  ? 212 LEU A HD23 1 
ATOM   3278 N  N    . SER A 1 213 ? 13.08700  -22.41100 -46.21900 1.000 32.83552  ? 213 SER A N    1 
ATOM   3279 C  CA   . SER A 1 213 ? 12.96900  -21.08500 -46.81300 1.000 30.82738  ? 213 SER A CA   1 
ATOM   3280 C  C    . SER A 1 213 ? 12.23000  -20.15000 -45.86400 1.000 32.59865  ? 213 SER A C    1 
ATOM   3281 O  O    . SER A 1 213 ? 11.03600  -20.32500 -45.59600 1.000 33.41716  ? 213 SER A O    1 
ATOM   3282 C  CB   . SER A 1 213 ? 12.24400  -21.15800 -48.15300 1.000 33.64614  ? 213 SER A CB   1 
ATOM   3283 O  OG   . SER A 1 213 ? 11.86700  -19.85900 -48.58600 1.000 35.51478  ? 213 SER A OG   1 
ATOM   3284 H  H    . SER A 1 213 ? 12.40500  -22.91500 -46.36100 1.000 39.41000  ? 213 SER A H    1 
ATOM   3285 H  HA   . SER A 1 213 ? 13.86300  -20.73400 -46.94800 1.000 36.99000  ? 213 SER A HA   1 
ATOM   3286 H  HB2  . SER A 1 213 ? 12.83500  -21.55300 -48.81200 1.000 40.38000  ? 213 SER A HB2  1 
ATOM   3287 H  HB3  . SER A 1 213 ? 11.44700  -21.70200 -48.05300 1.000 40.38000  ? 213 SER A HB3  1 
ATOM   3288 H  HG   . SER A 1 213 ? 12.54600  -19.36800 -48.64700 1.000 42.62000  ? 213 SER A HG   1 
ATOM   3289 N  N    . TYR A 1 214 ? 12.94500  -19.14600 -45.36300 1.000 34.12251  ? 214 TYR A N    1 
ATOM   3290 C  CA   . TYR A 1 214 ? 12.30700  -18.11000 -44.55600 1.000 34.62520  ? 214 TYR A CA   1 
ATOM   3291 C  C    . TYR A 1 214 ? 11.27200  -17.35000 -45.37800 1.000 36.68071  ? 214 TYR A C    1 
ATOM   3292 O  O    . TYR A 1 214 ? 10.18900  -17.02600 -44.87800 1.000 34.02513  ? 214 TYR A O    1 
ATOM   3293 C  CB   . TYR A 1 214 ? 13.38800  -17.18600 -43.99100 1.000 33.51191  ? 214 TYR A CB   1 
ATOM   3294 C  CG   . TYR A 1 214 ? 12.98300  -16.30300 -42.83800 1.000 31.41166  ? 214 TYR A CG   1 
ATOM   3295 C  CD1  . TYR A 1 214 ? 12.06000  -16.72300 -41.89600 1.000 32.04595  ? 214 TYR A CD1  1 
ATOM   3296 C  CD2  . TYR A 1 214 ? 13.56200  -15.05300 -42.68200 1.000 32.65128  ? 214 TYR A CD2  1 
ATOM   3297 C  CE1  . TYR A 1 214 ? 11.70100  -15.89900 -40.82800 1.000 33.15134  ? 214 TYR A CE1  1 
ATOM   3298 C  CE2  . TYR A 1 214 ? 13.21700  -14.23200 -41.63800 1.000 36.45963  ? 214 TYR A CE2  1 
ATOM   3299 C  CZ   . TYR A 1 214 ? 12.29500  -14.66100 -40.70400 1.000 36.09380  ? 214 TYR A CZ   1 
ATOM   3300 O  OH   . TYR A 1 214 ? 11.97000  -13.81800 -39.66500 1.000 35.58058  ? 214 TYR A OH   1 
ATOM   3301 H  H    . TYR A 1 214 ? 13.79100  -19.04100 -45.47500 1.000 40.95000  ? 214 TYR A H    1 
ATOM   3302 H  HA   . TYR A 1 214 ? 11.83600  -18.50400 -43.80500 1.000 41.55000  ? 214 TYR A HA   1 
ATOM   3303 H  HB2  . TYR A 1 214 ? 14.12400  -17.73700 -43.68200 1.000 40.21000  ? 214 TYR A HB2  1 
ATOM   3304 H  HB3  . TYR A 1 214 ? 13.68800  -16.60200 -44.70500 1.000 40.21000  ? 214 TYR A HB3  1 
ATOM   3305 H  HD1  . TYR A 1 214 ? 11.67300  -17.56500 -41.97600 1.000 38.46000  ? 214 TYR A HD1  1 
ATOM   3306 H  HD2  . TYR A 1 214 ? 14.19700  -14.76400 -43.29800 1.000 39.18000  ? 214 TYR A HD2  1 
ATOM   3307 H  HE1  . TYR A 1 214 ? 11.06900  -16.18100 -40.20700 1.000 39.78000  ? 214 TYR A HE1  1 
ATOM   3308 H  HE2  . TYR A 1 214 ? 13.60300  -13.39000 -41.55900 1.000 43.75000  ? 214 TYR A HE2  1 
ATOM   3309 H  HH   . TYR A 1 214 ? 12.42900  -13.11600 -39.71000 1.000 42.70000  ? 214 TYR A HH   1 
ATOM   3310 N  N    . GLU A 1 215 ? 11.56700  -17.08500 -46.65300 1.000 33.86722  ? 215 GLU A N    1 
ATOM   3311 C  CA   . GLU A 1 215 ? 10.60700  -16.37400 -47.48600 1.000 37.63346  ? 215 GLU A CA   1 
ATOM   3312 C  C    . GLU A 1 215 ? 9.31100   -17.16300 -47.62000 1.000 36.87021  ? 215 GLU A C    1 
ATOM   3313 O  O    . GLU A 1 215 ? 8.21800   -16.59300 -47.56800 1.000 37.26499  ? 215 GLU A O    1 
ATOM   3314 C  CB   . GLU A 1 215 ? 11.21100  -16.07200 -48.86200 1.000 40.41537  ? 215 GLU A CB   1 
ATOM   3315 C  CG   . GLU A 1 215 ? 12.20500  -14.89900 -48.85900 1.000 54.89079  ? 215 GLU A CG   1 
ATOM   3316 C  CD   . GLU A 1 215 ? 11.65500  -13.65200 -48.16900 1.000 65.87632  ? 215 GLU A CD   1 
ATOM   3317 O  OE1  . GLU A 1 215 ? 10.56700  -13.19200 -48.56800 1.000 50.99822  ? 215 GLU A OE1  1 
ATOM   3318 O  OE2  . GLU A 1 215 ? 12.29900  -13.15500 -47.20800 1.000 71.70860  ? 215 GLU A OE2  1 
ATOM   3319 H  H    . GLU A 1 215 ? 12.30000  -17.30200 -47.04800 1.000 40.64000  ? 215 GLU A H    1 
ATOM   3320 H  HA   . GLU A 1 215 ? 10.39900  -15.52300 -47.06800 1.000 45.16000  ? 215 GLU A HA   1 
ATOM   3321 H  HB2  . GLU A 1 215 ? 11.68300  -16.86000 -49.17400 1.000 48.50000  ? 215 GLU A HB2  1 
ATOM   3322 H  HB3  . GLU A 1 215 ? 10.49300  -15.85000 -49.47600 1.000 48.50000  ? 215 GLU A HB3  1 
ATOM   3323 H  HG2  . GLU A 1 215 ? 13.01000  -15.17000 -48.39100 1.000 65.87000  ? 215 GLU A HG2  1 
ATOM   3324 H  HG3  . GLU A 1 215 ? 12.41700  -14.66400 -49.77600 1.000 65.87000  ? 215 GLU A HG3  1 
ATOM   3325 N  N    . GLN A 1 216 ? 9.40600   -18.48100 -47.76700 1.000 35.98853  ? 216 GLN A N    1 
ATOM   3326 C  CA   . GLN A 1 216 ? 8.18600   -19.27200 -47.87800 1.000 37.30184  ? 216 GLN A CA   1 
ATOM   3327 C  C    . GLN A 1 216 ? 7.41100   -19.27600 -46.56100 1.000 36.01484  ? 216 GLN A C    1 
ATOM   3328 O  O    . GLN A 1 216 ? 6.17600   -19.25500 -46.55900 1.000 38.36249  ? 216 GLN A O    1 
ATOM   3329 C  CB   . GLN A 1 216 ? 8.51600   -20.69800 -48.30900 1.000 40.20219  ? 216 GLN A CB   1 
ATOM   3330 C  CG   . GLN A 1 216 ? 7.29800   -21.46000 -48.78400 1.000 52.29838  ? 216 GLN A CG   1 
ATOM   3331 C  CD   . GLN A 1 216 ? 6.61600   -20.77300 -49.95400 1.000 57.65428  ? 216 GLN A CD   1 
ATOM   3332 O  OE1  . GLN A 1 216 ? 7.25200   -20.47700 -50.96600 1.000 52.95635  ? 216 GLN A OE1  1 
ATOM   3333 N  NE2  . GLN A 1 216 ? 5.32400   -20.48100 -49.80400 1.000 52.67737  ? 216 GLN A NE2  1 
ATOM   3334 H  H    . GLN A 1 216 ? 10.14100  -18.92700 -47.80500 1.000 43.19000  ? 216 GLN A H    1 
ATOM   3335 H  HA   . GLN A 1 216 ? 7.62200   -18.87900 -48.56100 1.000 44.76000  ? 216 GLN A HA   1 
ATOM   3336 H  HB2  . GLN A 1 216 ? 9.15600   -20.66800 -49.03700 1.000 48.24000  ? 216 GLN A HB2  1 
ATOM   3337 H  HB3  . GLN A 1 216 ? 8.89500   -21.17700 -47.55500 1.000 48.24000  ? 216 GLN A HB3  1 
ATOM   3338 H  HG2  . GLN A 1 216 ? 7.56800   -22.34700 -49.06900 1.000 62.76000  ? 216 GLN A HG2  1 
ATOM   3339 H  HG3  . GLN A 1 216 ? 6.65900   -21.52500 -48.05700 1.000 62.76000  ? 216 GLN A HG3  1 
ATOM   3340 H  HE21 . GLN A 1 216 ? 4.91900   -20.68200 -49.07200 1.000 63.21000  ? 216 GLN A HE21 1 
ATOM   3341 H  HE22 . GLN A 1 216 ? 4.89400   -20.09100 -50.44000 1.000 63.21000  ? 216 GLN A HE22 1 
ATOM   3342 N  N    . PHE A 1 217 ? 8.12200   -19.31300 -45.43500 1.000 35.33582  ? 217 PHE A N    1 
ATOM   3343 C  CA   . PHE A 1 217 ? 7.47200   -19.22800 -44.12900 1.000 36.37805  ? 217 PHE A CA   1 
ATOM   3344 C  C    . PHE A 1 217 ? 6.67500   -17.93400 -44.00900 1.000 36.89916  ? 217 PHE A C    1 
ATOM   3345 O  O    . PHE A 1 217 ? 5.61100   -17.91200 -43.38200 1.000 34.48045  ? 217 PHE A O    1 
ATOM   3346 C  CB   . PHE A 1 217 ? 8.57000   -19.35100 -43.06700 1.000 33.03554  ? 217 PHE A CB   1 
ATOM   3347 C  CG   . PHE A 1 217 ? 8.09200   -19.66600 -41.65900 1.000 32.14070  ? 217 PHE A CG   1 
ATOM   3348 C  CD1  . PHE A 1 217 ? 7.25600   -20.73300 -41.39600 1.000 33.91722  ? 217 PHE A CD1  1 
ATOM   3349 C  CD2  . PHE A 1 217 ? 8.57300   -18.93100 -40.59800 1.000 35.17264  ? 217 PHE A CD2  1 
ATOM   3350 C  CE1  . PHE A 1 217 ? 6.87300   -21.02400 -40.10100 1.000 37.07287  ? 217 PHE A CE1  1 
ATOM   3351 C  CE2  . PHE A 1 217 ? 8.20600   -19.22600 -39.30600 1.000 34.02513  ? 217 PHE A CE2  1 
ATOM   3352 C  CZ   . PHE A 1 217 ? 7.34800   -20.26600 -39.06500 1.000 32.96711  ? 217 PHE A CZ   1 
ATOM   3353 H  H    . PHE A 1 217 ? 8.97900   -19.38600 -45.39900 1.000 42.40000  ? 217 PHE A H    1 
ATOM   3354 H  HA   . PHE A 1 217 ? 6.83800   -19.94800 -43.98800 1.000 43.65000  ? 217 PHE A HA   1 
ATOM   3355 H  HB2  . PHE A 1 217 ? 9.17200   -20.06400 -43.33300 1.000 39.65000  ? 217 PHE A HB2  1 
ATOM   3356 H  HB3  . PHE A 1 217 ? 9.05000   -18.50900 -43.02700 1.000 39.65000  ? 217 PHE A HB3  1 
ATOM   3357 H  HD1  . PHE A 1 217 ? 6.94800   -21.26100 -42.09700 1.000 40.70000  ? 217 PHE A HD1  1 
ATOM   3358 H  HD2  . PHE A 1 217 ? 9.15600   -18.22400 -40.75800 1.000 42.21000  ? 217 PHE A HD2  1 
ATOM   3359 H  HE1  . PHE A 1 217 ? 6.29400   -21.73200 -39.93400 1.000 44.49000  ? 217 PHE A HE1  1 
ATOM   3360 H  HE2  . PHE A 1 217 ? 8.53800   -18.72200 -38.59900 1.000 40.83000  ? 217 PHE A HE2  1 
ATOM   3361 H  HZ   . PHE A 1 217 ? 7.08700   -20.45800 -38.19400 1.000 39.56000  ? 217 PHE A HZ   1 
ATOM   3362 N  N    . LYS A 1 218 ? 7.15600   -16.85400 -44.62900 1.000 36.41226  ? 218 LYS A N    1 
ATOM   3363 C  CA   . LYS A 1 218 ? 6.44700   -15.58000 -44.58700 1.000 35.79903  ? 218 LYS A CA   1 
ATOM   3364 C  C    . LYS A 1 218 ? 5.23800   -15.57800 -45.51200 1.000 39.22049  ? 218 LYS A C    1 
ATOM   3365 O  O    . LYS A 1 218 ? 4.22100   -14.93300 -45.21800 1.000 39.11258  ? 218 LYS A O    1 
ATOM   3366 C  CB   . LYS A 1 218 ? 7.38600   -14.44800 -44.98900 1.000 36.66492  ? 218 LYS A CB   1 
ATOM   3367 C  CG   . LYS A 1 218 ? 8.41500   -14.09000 -43.94400 1.000 36.72282  ? 218 LYS A CG   1 
ATOM   3368 C  CD   . LYS A 1 218 ? 9.44000   -13.14500 -44.52000 1.000 38.35197  ? 218 LYS A CD   1 
ATOM   3369 C  CE   . LYS A 1 218 ? 10.45300  -12.71000 -43.47700 1.000 43.68682  ? 218 LYS A CE   1 
ATOM   3370 N  NZ   . LYS A 1 218 ? 11.51300  -11.84200 -44.10000 1.000 42.66564  ? 218 LYS A NZ   1 
ATOM   3371 H  H    . LYS A 1 218 ? 7.88900   -16.83500 -45.08000 1.000 43.69000  ? 218 LYS A H    1 
ATOM   3372 H  HA   . LYS A 1 218 ? 6.14300   -15.43000 -43.67800 1.000 42.96000  ? 218 LYS A HA   1 
ATOM   3373 H  HB2  . LYS A 1 218 ? 7.86200   -14.71200 -45.79200 1.000 44.00000  ? 218 LYS A HB2  1 
ATOM   3374 H  HB3  . LYS A 1 218 ? 6.85700   -13.65400 -45.16400 1.000 44.00000  ? 218 LYS A HB3  1 
ATOM   3375 H  HG2  . LYS A 1 218 ? 7.98000   -13.65600 -43.19300 1.000 44.07000  ? 218 LYS A HG2  1 
ATOM   3376 H  HG3  . LYS A 1 218 ? 8.86900   -14.89400 -43.64500 1.000 44.07000  ? 218 LYS A HG3  1 
ATOM   3377 H  HD2  . LYS A 1 218 ? 9.91700   -13.58800 -45.24000 1.000 46.02000  ? 218 LYS A HD2  1 
ATOM   3378 H  HD3  . LYS A 1 218 ? 8.99200   -12.35300 -44.85700 1.000 46.02000  ? 218 LYS A HD3  1 
ATOM   3379 H  HE2  . LYS A 1 218 ? 10.00600  -12.20100 -42.78200 1.000 52.43000  ? 218 LYS A HE2  1 
ATOM   3380 H  HE3  . LYS A 1 218 ? 10.88000  -13.49100 -43.09300 1.000 52.43000  ? 218 LYS A HE3  1 
ATOM   3381 H  HZ1  . LYS A 1 218 ? 12.10200  -11.59100 -43.48300 1.000 51.20000  ? 218 LYS A HZ1  1 
ATOM   3382 H  HZ2  . LYS A 1 218 ? 11.93800  -12.29300 -44.74000 1.000 51.20000  ? 218 LYS A HZ2  1 
ATOM   3383 H  HZ3  . LYS A 1 218 ? 11.14100  -11.11600 -44.45700 1.000 51.20000  ? 218 LYS A HZ3  1 
ATOM   3384 N  N    . LYS A 1 219 ? 5.34800   -16.26200 -46.65200 1.000 40.37853  ? 219 LYS A N    1 
ATOM   3385 C  CA   . LYS A 1 219 ? 4.23600   -16.33600 -47.58900 1.000 42.27875  ? 219 LYS A CA   1 
ATOM   3386 C  C    . LYS A 1 219 ? 3.17100   -17.30400 -47.09500 1.000 41.82870  ? 219 LYS A C    1 
ATOM   3387 O  O    . LYS A 1 219 ? 1.97100   -17.05900 -47.26700 1.000 46.37661  ? 219 LYS A O    1 
ATOM   3388 C  CB   . LYS A 1 219 ? 4.74000   -16.75400 -48.97700 1.000 43.70524  ? 219 LYS A CB   1 
ATOM   3389 C  CG   . LYS A 1 219 ? 5.66700   -15.73600 -49.64900 1.000 54.44863  ? 219 LYS A CG   1 
ATOM   3390 C  CD   . LYS A 1 219 ? 6.13500   -16.16400 -51.06300 1.000 64.80777  ? 219 LYS A CD   1 
ATOM   3391 C  CE   . LYS A 1 219 ? 5.21700   -15.65500 -52.18200 1.000 100.21728 ? 219 LYS A CE   1 
ATOM   3392 N  NZ   . LYS A 1 219 ? 5.31600   -16.45400 -53.44900 1.000 92.94009  ? 219 LYS A NZ   1 
ATOM   3393 H  H    . LYS A 1 219 ? 6.05200   -16.68800 -46.90100 1.000 48.45000  ? 219 LYS A H    1 
ATOM   3394 H  HA   . LYS A 1 219 ? 3.83500   -15.45700 -47.67600 1.000 50.73000  ? 219 LYS A HA   1 
ATOM   3395 H  HB2  . LYS A 1 219 ? 5.23100   -17.58500 -48.88900 1.000 52.45000  ? 219 LYS A HB2  1 
ATOM   3396 H  HB3  . LYS A 1 219 ? 3.97300   -16.88100 -49.55800 1.000 52.45000  ? 219 LYS A HB3  1 
ATOM   3397 H  HG2  . LYS A 1 219 ? 5.19500   -14.89300 -49.73600 1.000 65.34000  ? 219 LYS A HG2  1 
ATOM   3398 H  HG3  . LYS A 1 219 ? 6.45600   -15.62000 -49.09800 1.000 65.34000  ? 219 LYS A HG3  1 
ATOM   3399 H  HD2  . LYS A 1 219 ? 7.02300   -15.80800 -51.22100 1.000 77.77000  ? 219 LYS A HD2  1 
ATOM   3400 H  HD3  . LYS A 1 219 ? 6.15200   -17.13200 -51.10900 1.000 77.77000  ? 219 LYS A HD3  1 
ATOM   3401 H  HE2  . LYS A 1 219 ? 4.29800   -15.69700 -51.87600 1.000 120.26000 ? 219 LYS A HE2  1 
ATOM   3402 H  HE3  . LYS A 1 219 ? 5.45600   -14.73900 -52.39000 1.000 120.26000 ? 219 LYS A HE3  1 
ATOM   3403 H  HZ1  . LYS A 1 219 ? 4.76900   -16.11700 -54.06500 1.000 111.53000 ? 219 LYS A HZ1  1 
ATOM   3404 H  HZ2  . LYS A 1 219 ? 6.15000   -16.43200 -53.75900 1.000 111.53000 ? 219 LYS A HZ2  1 
ATOM   3405 H  HZ3  . LYS A 1 219 ? 5.08800   -17.30100 -53.29300 1.000 111.53000 ? 219 LYS A HZ3  1 
ATOM   3406 N  N    . GLY A 1 220 ? 3.59300   -18.39100 -46.46600 1.000 40.26272  ? 220 GLY A N    1 
ATOM   3407 C  CA   . GLY A 1 220 ? 2.67700   -19.41600 -46.03100 1.000 41.97082  ? 220 GLY A CA   1 
ATOM   3408 C  C    . GLY A 1 220 ? 3.15100   -20.79000 -46.43800 1.000 41.70237  ? 220 GLY A C    1 
ATOM   3409 O  O    . GLY A 1 220 ? 3.57400   -20.99600 -47.58100 1.000 40.54960  ? 220 GLY A O    1 
ATOM   3410 H  H    . GLY A 1 220 ? 4.41700   -18.55600 -46.28000 1.000 48.31000  ? 220 GLY A H    1 
ATOM   3411 H  HA2  . GLY A 1 220 ? 2.59600   -19.38900 -45.06500 1.000 50.36000  ? 220 GLY A HA2  1 
ATOM   3412 H  HA3  . GLY A 1 220 ? 1.80500   -19.25900 -46.42600 1.000 50.36000  ? 220 GLY A HA3  1 
ATOM   3413 N  N    . VAL A 1 221 ? 3.12600   -21.72500 -45.49800 1.000 38.81781  ? 221 VAL A N    1 
ATOM   3414 C  CA   . VAL A 1 221 ? 3.42600   -23.11800 -45.77800 1.000 41.46023  ? 221 VAL A CA   1 
ATOM   3415 C  C    . VAL A 1 221 ? 2.19300   -23.94100 -45.45100 1.000 44.30268  ? 221 VAL A C    1 
ATOM   3416 O  O    . VAL A 1 221 ? 1.45200   -23.65000 -44.50200 1.000 39.72318  ? 221 VAL A O    1 
ATOM   3417 C  CB   . VAL A 1 221 ? 4.64300   -23.64600 -44.99600 1.000 41.85239  ? 221 VAL A CB   1 
ATOM   3418 C  CG1  . VAL A 1 221 ? 5.89600   -22.92000 -45.44700 1.000 43.34467  ? 221 VAL A CG1  1 
ATOM   3419 C  CG2  . VAL A 1 221 ? 4.41800   -23.49700 -43.48400 1.000 38.60726  ? 221 VAL A CG2  1 
ATOM   3420 H  H    . VAL A 1 221 ? 2.93500   -21.57200 -44.67400 1.000 46.58000  ? 221 VAL A H    1 
ATOM   3421 H  HA   . VAL A 1 221 ? 3.63100   -23.20500 -46.72200 1.000 49.75000  ? 221 VAL A HA   1 
ATOM   3422 H  HB   . VAL A 1 221 ? 4.76300   -24.59100 -45.17700 1.000 50.22000  ? 221 VAL A HB   1 
ATOM   3423 H  HG11 . VAL A 1 221 ? 6.65700   -23.27300 -44.96100 1.000 52.01000  ? 221 VAL A HG11 1 
ATOM   3424 H  HG12 . VAL A 1 221 ? 6.01700   -23.06100 -46.39900 1.000 52.01000  ? 221 VAL A HG12 1 
ATOM   3425 H  HG13 . VAL A 1 221 ? 5.79600   -21.97300 -45.26300 1.000 52.01000  ? 221 VAL A HG13 1 
ATOM   3426 H  HG21 . VAL A 1 221 ? 5.22700   -23.75800 -43.01800 1.000 46.33000  ? 221 VAL A HG21 1 
ATOM   3427 H  HG22 . VAL A 1 221 ? 4.20500   -22.57200 -43.28600 1.000 46.33000  ? 221 VAL A HG22 1 
ATOM   3428 H  HG23 . VAL A 1 221 ? 3.68300   -24.07100 -43.21700 1.000 46.33000  ? 221 VAL A HG23 1 
ATOM   3429 N  N    . GLN A 1 222 ? 1.98200   -24.98300 -46.24700 1.000 45.11067  ? 222 GLN A N    1 
ATOM   3430 C  CA   . GLN A 1 222 ? 0.84400   -25.87200 -46.07000 1.000 44.70536  ? 222 GLN A CA   1 
ATOM   3431 C  C    . GLN A 1 222 ? 1.18700   -26.94500 -45.05900 1.000 43.12622  ? 222 GLN A C    1 
ATOM   3432 O  O    . GLN A 1 222 ? 2.24200   -27.57800 -45.15100 1.000 40.62329  ? 222 GLN A O    1 
ATOM   3433 C  CB   . GLN A 1 222 ? 0.45100   -26.49800 -47.40600 1.000 48.25315  ? 222 GLN A CB   1 
ATOM   3434 C  CG   . GLN A 1 222 ? 0.40900   -25.45900 -48.47800 1.000 49.36908  ? 222 GLN A CG   1 
ATOM   3435 C  CD   . GLN A 1 222 ? -0.61100  -24.40500 -48.14800 1.000 51.27720  ? 222 GLN A CD   1 
ATOM   3436 O  OE1  . GLN A 1 222 ? -0.29500  -23.21600 -48.07400 1.000 53.18532  ? 222 GLN A OE1  1 
ATOM   3437 N  NE2  . GLN A 1 222 ? -1.84700  -24.83600 -47.92300 1.000 53.30376  ? 222 GLN A NE2  1 
ATOM   3438 H  H    . GLN A 1 222 ? 2.49200   -25.19800 -46.90500 1.000 54.13000  ? 222 GLN A H    1 
ATOM   3439 H  HA   . GLN A 1 222 ? 0.08400   -25.37300 -45.73300 1.000 53.65000  ? 222 GLN A HA   1 
ATOM   3440 H  HB2  . GLN A 1 222 ? 1.10300   -27.17200 -47.65300 1.000 57.90000  ? 222 GLN A HB2  1 
ATOM   3441 H  HB3  . GLN A 1 222 ? -0.42900  -26.90000 -47.32900 1.000 57.90000  ? 222 GLN A HB3  1 
ATOM   3442 H  HG2  . GLN A 1 222 ? 1.27800   -25.03600 -48.55400 1.000 59.24000  ? 222 GLN A HG2  1 
ATOM   3443 H  HG3  . GLN A 1 222 ? 0.16500   -25.87200 -49.32100 1.000 59.24000  ? 222 GLN A HG3  1 
ATOM   3444 H  HE21 . GLN A 1 222 ? -2.02500  -25.67700 -47.97100 1.000 63.96000  ? 222 GLN A HE21 1 
ATOM   3445 H  HE22 . GLN A 1 222 ? -2.47000  -24.27500 -47.73000 1.000 63.96000  ? 222 GLN A HE22 1 
ATOM   3446 N  N    . ILE A 1 223 ? 0.30600   -27.11700 -44.08100 1.000 41.58657  ? 223 ILE A N    1 
ATOM   3447 C  CA   . ILE A 1 223 ? 0.44000   -28.14700 -43.05600 1.000 39.31261  ? 223 ILE A CA   1 
ATOM   3448 C  C    . ILE A 1 223 ? -0.91000  -28.81200 -42.86700 1.000 41.22073  ? 223 ILE A C    1 
ATOM   3449 O  O    . ILE A 1 223 ? -1.95700  -28.24300 -43.20500 1.000 45.38965  ? 223 ILE A O    1 
ATOM   3450 C  CB   . ILE A 1 223 ? 0.93800   -27.57100 -41.71500 1.000 44.81853  ? 223 ILE A CB   1 
ATOM   3451 C  CG1  . ILE A 1 223 ? -0.02400  -26.50100 -41.19800 1.000 40.99439  ? 223 ILE A CG1  1 
ATOM   3452 C  CG2  . ILE A 1 223 ? 2.35000   -27.00300 -41.87800 1.000 43.26835  ? 223 ILE A CG2  1 
ATOM   3453 C  CD1  . ILE A 1 223 ? 0.26200   -26.03900 -39.77700 1.000 41.07335  ? 223 ILE A CD1  1 
ATOM   3454 H  H    . ILE A 1 223 ? -0.40000  -26.63500 -43.98600 1.000 49.90000  ? 223 ILE A H    1 
ATOM   3455 H  HA   . ILE A 1 223 ? 1.07900   -28.81600 -43.34800 1.000 47.18000  ? 223 ILE A HA   1 
ATOM   3456 H  HB   . ILE A 1 223 ? 0.96700   -28.28900 -41.06300 1.000 53.78000  ? 223 ILE A HB   1 
ATOM   3457 H  HG12 . ILE A 1 223 ? 0.03500   -25.72600 -41.77700 1.000 49.19000  ? 223 ILE A HG12 1 
ATOM   3458 H  HG13 . ILE A 1 223 ? -0.92500  -26.86000 -41.21500 1.000 49.19000  ? 223 ILE A HG13 1 
ATOM   3459 H  HG21 . ILE A 1 223 ? 2.67800   -26.71800 -41.01000 1.000 51.92000  ? 223 ILE A HG21 1 
ATOM   3460 H  HG22 . ILE A 1 223 ? 2.92800   -27.69300 -42.23900 1.000 51.92000  ? 223 ILE A HG22 1 
ATOM   3461 H  HG23 . ILE A 1 223 ? 2.31800   -26.24700 -42.48400 1.000 51.92000  ? 223 ILE A HG23 1 
ATOM   3462 H  HD11 . ILE A 1 223 ? -0.40100  -25.37900 -39.52000 1.000 49.29000  ? 223 ILE A HD11 1 
ATOM   3463 H  HD12 . ILE A 1 223 ? 0.21600   -26.80300 -39.18100 1.000 49.29000  ? 223 ILE A HD12 1 
ATOM   3464 H  HD13 . ILE A 1 223 ? 1.14900   -25.64700 -39.74500 1.000 49.29000  ? 223 ILE A HD13 1 
ATOM   3465 N  N    . PRO A 1 224 ? -0.91900  -30.01500 -42.30600 1.000 45.83707  ? 224 PRO A N    1 
ATOM   3466 C  CA   . PRO A 1 224 ? -2.19600  -30.68700 -42.04100 1.000 49.07167  ? 224 PRO A CA   1 
ATOM   3467 C  C    . PRO A 1 224 ? -3.05400  -29.90100 -41.06400 1.000 46.78456  ? 224 PRO A C    1 
ATOM   3468 O  O    . PRO A 1 224 ? -2.55300  -29.30600 -40.10500 1.000 44.61588  ? 224 PRO A O    1 
ATOM   3469 C  CB   . PRO A 1 224 ? -1.76800  -32.03600 -41.44300 1.000 48.05839  ? 224 PRO A CB   1 
ATOM   3470 C  CG   . PRO A 1 224 ? -0.36800  -32.23900 -41.94000 1.000 50.88768  ? 224 PRO A CG   1 
ATOM   3471 C  CD   . PRO A 1 224 ? 0.23100   -30.85700 -41.92900 1.000 50.19812  ? 224 PRO A CD   1 
ATOM   3472 H  HA   . PRO A 1 224 ? -2.68500  -30.82500 -42.86800 1.000 58.88000  ? 224 PRO A HA   1 
ATOM   3473 H  HB2  . PRO A 1 224 ? -1.79100  -31.99300 -40.47400 1.000 57.67000  ? 224 PRO A HB2  1 
ATOM   3474 H  HB3  . PRO A 1 224 ? -2.35600  -32.74100 -41.75800 1.000 57.67000  ? 224 PRO A HB3  1 
ATOM   3475 H  HG2  . PRO A 1 224 ? 0.11400   -32.83500 -41.34600 1.000 61.06000  ? 224 PRO A HG2  1 
ATOM   3476 H  HG3  . PRO A 1 224 ? -0.38300  -32.60700 -42.83800 1.000 61.06000  ? 224 PRO A HG3  1 
ATOM   3477 H  HD2  . PRO A 1 224 ? 0.55800   -30.62600 -41.04500 1.000 60.24000  ? 224 PRO A HD2  1 
ATOM   3478 H  HD3  . PRO A 1 224 ? 0.94700   -30.78200 -42.57800 1.000 60.24000  ? 224 PRO A HD3  1 
ATOM   3479 N  N    . CYS A 1 225 ? -4.35700  -29.90400 -41.31500 1.000 42.15505  ? 225 CYS A N    1 
ATOM   3480 C  CA   . CYS A 1 225 ? -5.34200  -29.48900 -40.33400 1.000 39.76793  ? 225 CYS A CA   1 
ATOM   3481 C  C    . CYS A 1 225 ? -6.04600  -30.71900 -39.78500 1.000 45.38176  ? 225 CYS A C    1 
ATOM   3482 O  O    . CYS A 1 225 ? -6.17800  -31.73900 -40.47200 1.000 44.08950  ? 225 CYS A O    1 
ATOM   3483 C  CB   . CYS A 1 225 ? -6.38200  -28.53300 -40.92000 1.000 41.51550  ? 225 CYS A CB   1 
ATOM   3484 S  SG   . CYS A 1 225 ? -7.47500  -27.80400 -39.62800 1.000 40.32326  ? 225 CYS A SG   1 
ATOM   3485 H  H    . CYS A 1 225 ? -4.69900  -30.14900 -42.06500 1.000 50.59000  ? 225 CYS A H    1 
ATOM   3486 H  HA   . CYS A 1 225 ? -4.89200  -29.01800 -39.61500 1.000 47.72000  ? 225 CYS A HA   1 
ATOM   3487 H  HB2  . CYS A 1 225 ? -5.92600  -27.80700 -41.37400 1.000 49.82000  ? 225 CYS A HB2  1 
ATOM   3488 H  HB3  . CYS A 1 225 ? -6.94000  -29.01900 -41.54800 1.000 49.82000  ? 225 CYS A HB3  1 
ATOM   3489 N  N    . THR A 1 226 ? -6.51200  -30.61600 -38.53700 1.000 41.91818  ? 226 THR A N    1 
ATOM   3490 C  CA   . THR A 1 226 ? -7.23300  -31.73300 -37.95200 1.000 44.45533  ? 226 THR A CA   1 
ATOM   3491 C  C    . THR A 1 226 ? -8.49600  -32.07600 -38.73500 1.000 51.37195  ? 226 THR A C    1 
ATOM   3492 O  O    . THR A 1 226 ? -8.97400  -33.21300 -38.65100 1.000 53.32481  ? 226 THR A O    1 
ATOM   3493 C  CB   . THR A 1 226 ? -7.58800  -31.44300 -36.48900 1.000 48.89797  ? 226 THR A CB   1 
ATOM   3494 O  OG1  . THR A 1 226 ? -8.39200  -32.52000 -35.99000 1.000 60.79413  ? 226 THR A OG1  1 
ATOM   3495 C  CG2  . THR A 1 226 ? -8.36200  -30.13700 -36.31900 1.000 47.27935  ? 226 THR A CG2  1 
ATOM   3496 H  H    . THR A 1 226 ? -6.42300  -29.92900 -38.02800 1.000 50.30000  ? 226 THR A H    1 
ATOM   3497 H  HA   . THR A 1 226 ? -6.65200  -32.51000 -37.96300 1.000 53.35000  ? 226 THR A HA   1 
ATOM   3498 H  HB   . THR A 1 226 ? -6.76400  -31.35300 -35.98400 1.000 58.68000  ? 226 THR A HB   1 
ATOM   3499 H  HG1  . THR A 1 226 ? -8.63400  -32.35700 -35.20200 1.000 72.96000  ? 226 THR A HG1  1 
ATOM   3500 H  HG21 . THR A 1 226 ? -8.56000  -29.98800 -35.38100 1.000 56.74000  ? 226 THR A HG21 1 
ATOM   3501 H  HG22 . THR A 1 226 ? -7.83500  -29.39300 -36.65100 1.000 56.74000  ? 226 THR A HG22 1 
ATOM   3502 H  HG23 . THR A 1 226 ? -9.19500  -30.17900 -36.81400 1.000 56.74000  ? 226 THR A HG23 1 
ATOM   3503 N  N    . CYS A 1 227 ? -9.04900  -31.12900 -39.49700 1.000 48.85849  ? 227 CYS A N    1 
ATOM   3504 C  CA   . CYS A 1 227 ? -10.24400 -31.41200 -40.28400 1.000 44.23162  ? 227 CYS A CA   1 
ATOM   3505 C  C    . CYS A 1 227 ? -9.93900  -32.23400 -41.52700 1.000 46.37135  ? 227 CYS A C    1 
ATOM   3506 O  O    . CYS A 1 227 ? -10.87600 -32.62200 -42.24200 1.000 47.06617  ? 227 CYS A O    1 
ATOM   3507 C  CB   . CYS A 1 227 ? -10.94000 -30.10800 -40.68900 1.000 45.48440  ? 227 CYS A CB   1 
ATOM   3508 S  SG   . CYS A 1 227 ? -10.08600 -29.16700 -41.99200 1.000 43.23939  ? 227 CYS A SG   1 
ATOM   3509 H  H    . CYS A 1 227 ? -8.75300  -30.32500 -39.57100 1.000 58.63000  ? 227 CYS A H    1 
ATOM   3510 H  HA   . CYS A 1 227 ? -10.86500 -31.91400 -39.73400 1.000 53.08000  ? 227 CYS A HA   1 
ATOM   3511 H  HB2  . CYS A 1 227 ? -11.82900 -30.32100 -41.01500 1.000 54.58000  ? 227 CYS A HB2  1 
ATOM   3512 H  HB3  . CYS A 1 227 ? -11.00200 -29.53600 -39.90800 1.000 54.58000  ? 227 CYS A HB3  1 
ATOM   3513 N  N    . GLY A 1 228 ? -8.66300  -32.50100 -41.80200 1.000 46.71086  ? 228 GLY A N    1 
ATOM   3514 C  CA   . GLY A 1 228 ? -8.25400  -33.27300 -42.94400 1.000 46.46873  ? 228 GLY A CA   1 
ATOM   3515 C  C    . GLY A 1 228 ? -7.81000  -32.44300 -44.12700 1.000 40.46801  ? 228 GLY A C    1 
ATOM   3516 O  O    . GLY A 1 228 ? -7.12600  -32.96300 -45.00800 1.000 40.26535  ? 228 GLY A O    1 
ATOM   3517 H  H    . GLY A 1 228 ? -8.00500  -32.23200 -41.31900 1.000 56.05000  ? 228 GLY A H    1 
ATOM   3518 H  HA2  . GLY A 1 228 ? -7.51400  -33.84500 -42.68700 1.000 55.76000  ? 228 GLY A HA2  1 
ATOM   3519 H  HA3  . GLY A 1 228 ? -8.99700  -33.82700 -43.23100 1.000 55.76000  ? 228 GLY A HA3  1 
ATOM   3520 N  N    . LYS A 1 229 ? -8.18300  -31.17700 -44.16100 1.000 40.50222  ? 229 LYS A N    1 
ATOM   3521 C  CA   . LYS A 1 229 ? -7.74500  -30.27100 -45.24100 1.000 40.16271  ? 229 LYS A CA   1 
ATOM   3522 C  C    . LYS A 1 229 ? -6.35000  -29.77800 -44.88900 1.000 45.46598  ? 229 LYS A C    1 
ATOM   3523 O  O    . LYS A 1 229 ? -5.89400  -30.19200 -43.87600 1.000 42.42088  ? 229 LYS A O    1 
ATOM   3524 C  CB   . LYS A 1 229 ? -8.73300  -29.11700 -45.38700 1.000 42.27875  ? 229 LYS A CB   1 
ATOM   3525 C  CG   . LYS A 1 229 ? -10.16000 -29.54300 -45.68400 1.000 42.68670  ? 229 LYS A CG   1 
ATOM   3526 C  CD   . LYS A 1 229 ? -11.14700 -28.42400 -45.51800 1.000 47.20829  ? 229 LYS A CD   1 
ATOM   3527 C  CE   . LYS A 1 229 ? -10.95800 -27.28700 -46.49500 1.000 54.97501  ? 229 LYS A CE   1 
ATOM   3528 N  NZ   . LYS A 1 229 ? -10.84000 -27.77300 -47.88800 1.000 58.00169  ? 229 LYS A NZ   1 
ATOM   3529 H  H    . LYS A 1 229 ? -8.70800  -30.77700 -43.53000 1.000 48.60000  ? 229 LYS A H    1 
ATOM   3530 H  HA   . LYS A 1 229 ? -7.71000  -30.76900 -46.08700 1.000 48.19000  ? 229 LYS A HA   1 
ATOM   3531 H  HB2  . LYS A 1 229 ? -8.72700  -28.59500 -44.55900 1.000 50.74000  ? 229 LYS A HB2  1 
ATOM   3532 H  HB3  . LYS A 1 229 ? -8.42300  -28.53300 -46.11000 1.000 50.74000  ? 229 LYS A HB3  1 
ATOM   3533 H  HG2  . LYS A 1 229 ? -10.20500 -29.88700 -46.60000 1.000 51.23000  ? 229 LYS A HG2  1 
ATOM   3534 H  HG3  . LYS A 1 229 ? -10.40600 -30.27200 -45.07800 1.000 51.23000  ? 229 LYS A HG3  1 
ATOM   3535 H  HD2  . LYS A 1 229 ? -12.05300 -28.78200 -45.62100 1.000 56.65000  ? 229 LYS A HD2  1 
ATOM   3536 H  HD3  . LYS A 1 229 ? -11.06400 -28.07000 -44.60900 1.000 56.65000  ? 229 LYS A HD3  1 
ATOM   3537 H  HE2  . LYS A 1 229 ? -11.71700 -26.67800 -46.43400 1.000 65.97000  ? 229 LYS A HE2  1 
ATOM   3538 H  HE3  . LYS A 1 229 ? -10.15300 -26.78900 -46.26200 1.000 65.97000  ? 229 LYS A HE3  1 
ATOM   3539 H  HZ1  . LYS A 1 229 ? -11.40700 -28.46800 -48.01900 1.000 69.60000  ? 229 LYS A HZ1  1 
ATOM   3540 H  HZ2  . LYS A 1 229 ? -11.05000 -27.10500 -48.46300 1.000 69.60000  ? 229 LYS A HZ2  1 
ATOM   3541 H  HZ3  . LYS A 1 229 ? -9.98900  -28.04400 -48.04900 1.000 69.60000  ? 229 LYS A HZ3  1 
ATOM   3542 N  N    . GLN A 1 230 ? -5.67700  -29.04900 -45.76200 1.000 42.66564  ? 230 GLN A N    1 
ATOM   3543 C  CA   . GLN A 1 230 ? -4.41800  -28.37900 -45.47200 1.000 42.56826  ? 230 GLN A CA   1 
ATOM   3544 C  C    . GLN A 1 230 ? -4.70700  -26.99100 -44.91500 1.000 42.22085  ? 230 GLN A C    1 
ATOM   3545 O  O    . GLN A 1 230 ? -5.49500  -26.23400 -45.49200 1.000 45.82655  ? 230 GLN A O    1 
ATOM   3546 C  CB   . GLN A 1 230 ? -3.53900  -28.22700 -46.72100 1.000 47.45306  ? 230 GLN A CB   1 
ATOM   3547 C  CG   . GLN A 1 230 ? -3.40800  -29.43600 -47.63200 1.000 48.08998  ? 230 GLN A CG   1 
ATOM   3548 C  CD   . GLN A 1 230 ? -2.74500  -30.62800 -46.97200 1.000 57.46215  ? 230 GLN A CD   1 
ATOM   3549 O  OE1  . GLN A 1 230 ? -3.11100  -31.78000 -47.23200 1.000 62.02323  ? 230 GLN A OE1  1 
ATOM   3550 N  NE2  . GLN A 1 230 ? -1.75400  -30.36300 -46.12500 1.000 57.84641  ? 230 GLN A NE2  1 
ATOM   3551 H  H    . GLN A 1 230 ? -5.97400  -28.90900 -46.55800 1.000 51.20000  ? 230 GLN A H    1 
ATOM   3552 H  HA   . GLN A 1 230 ? -3.93300  -28.91400 -44.82500 1.000 51.08000  ? 230 GLN A HA   1 
ATOM   3553 H  HB2  . GLN A 1 230 ? -3.90700  -27.50900 -47.25900 1.000 56.94000  ? 230 GLN A HB2  1 
ATOM   3554 H  HB3  . GLN A 1 230 ? -2.64300  -27.99700 -46.42900 1.000 56.94000  ? 230 GLN A HB3  1 
ATOM   3555 H  HG2  . GLN A 1 230 ? -4.29400  -29.71100 -47.91600 1.000 57.71000  ? 230 GLN A HG2  1 
ATOM   3556 H  HG3  . GLN A 1 230 ? -2.87400  -29.19000 -48.40300 1.000 57.71000  ? 230 GLN A HG3  1 
ATOM   3557 H  HE21 . GLN A 1 230 ? -1.52100  -29.54800 -45.97800 1.000 69.41000  ? 230 GLN A HE21 1 
ATOM   3558 H  HE22 . GLN A 1 230 ? -1.34600  -31.00600 -45.72500 1.000 69.41000  ? 230 GLN A HE22 1 
ATOM   3559 N  N    . ALA A 1 231 ? -4.06900  -26.64400 -43.80700 1.000 47.37936  ? 231 ALA A N    1 
ATOM   3560 C  CA   . ALA A 1 231 ? -4.07000  -25.26300 -43.35200 1.000 46.91615  ? 231 ALA A CA   1 
ATOM   3561 C  C    . ALA A 1 231 ? -2.81100  -24.56100 -43.84700 1.000 43.56049  ? 231 ALA A C    1 
ATOM   3562 O  O    . ALA A 1 231 ? -1.83500  -25.19400 -44.26100 1.000 42.28139  ? 231 ALA A O    1 
ATOM   3563 C  CB   . ALA A 1 231 ? -4.15500  -25.17500 -41.82600 1.000 43.76314  ? 231 ALA A CB   1 
ATOM   3564 H  H    . ALA A 1 231 ? -3.63200  -27.18800 -43.30500 1.000 56.86000  ? 231 ALA A H    1 
ATOM   3565 H  HA   . ALA A 1 231 ? -4.84800  -24.80700 -43.70900 1.000 56.30000  ? 231 ALA A HA   1 
ATOM   3566 H  HB1  . ALA A 1 231 ? -4.16500  -24.24200 -41.56400 1.000 52.52000  ? 231 ALA A HB1  1 
ATOM   3567 H  HB2  . ALA A 1 231 ? -4.96900  -25.61100 -41.53000 1.000 52.52000  ? 231 ALA A HB2  1 
ATOM   3568 H  HB3  . ALA A 1 231 ? -3.38300  -25.61900 -41.44100 1.000 52.52000  ? 231 ALA A HB3  1 
ATOM   3569 N  N    . THR A 1 232 ? -2.84100  -23.23700 -43.79500 1.000 43.77367  ? 232 THR A N    1 
ATOM   3570 C  CA   . THR A 1 232 ? -1.68500  -22.41900 -44.14100 1.000 41.42865  ? 232 THR A CA   1 
ATOM   3571 C  C    . THR A 1 232 ? -1.14700  -21.78000 -42.87300 1.000 39.15996  ? 232 THR A C    1 
ATOM   3572 O  O    . THR A 1 232 ? -1.88800  -21.08800 -42.16900 1.000 37.47818  ? 232 THR A O    1 
ATOM   3573 C  CB   . THR A 1 232 ? -2.05800  -21.34700 -45.16700 1.000 45.63179  ? 232 THR A CB   1 
ATOM   3574 O  OG1  . THR A 1 232 ? -2.54500  -21.98400 -46.35300 1.000 47.52938  ? 232 THR A OG1  1 
ATOM   3575 C  CG2  . THR A 1 232 ? -0.84900  -20.49500 -45.49800 1.000 41.68658  ? 232 THR A CG2  1 
ATOM   3576 H  H    . THR A 1 232 ? -3.53100  -22.78100 -43.55800 1.000 52.53000  ? 232 THR A H    1 
ATOM   3577 H  HA   . THR A 1 232 ? -0.99200  -22.97900 -44.52500 1.000 49.72000  ? 232 THR A HA   1 
ATOM   3578 H  HB   . THR A 1 232 ? -2.74700  -20.76600 -44.80900 1.000 54.76000  ? 232 THR A HB   1 
ATOM   3579 H  HG1  . THR A 1 232 ? -1.96700  -22.51500 -46.65200 1.000 57.03000  ? 232 THR A HG1  1 
ATOM   3580 H  HG21 . THR A 1 232 ? -1.00500  -20.00200 -46.31800 1.000 50.02000  ? 232 THR A HG21 1 
ATOM   3581 H  HG22 . THR A 1 232 ? -0.68000  -19.86500 -44.77900 1.000 50.02000  ? 232 THR A HG22 1 
ATOM   3582 H  HG23 . THR A 1 232 ? -0.06700  -21.05800 -45.61200 1.000 50.02000  ? 232 THR A HG23 1 
ATOM   3583 N  N    . LYS A 1 233 ? 0.12600   -22.03400 -42.57800 1.000 37.81506  ? 233 LYS A N    1 
ATOM   3584 C  CA   . LYS A 1 233 ? 0.83000   -21.42500 -41.45900 1.000 37.55187  ? 233 LYS A CA   1 
ATOM   3585 C  C    . LYS A 1 233 ? 1.74800   -20.34900 -42.01300 1.000 36.94917  ? 233 LYS A C    1 
ATOM   3586 O  O    . LYS A 1 233 ? 2.55800   -20.62600 -42.90000 1.000 39.99164  ? 233 LYS A O    1 
ATOM   3587 C  CB   . LYS A 1 233 ? 1.64800   -22.46900 -40.69900 1.000 38.95993  ? 233 LYS A CB   1 
ATOM   3588 C  CG   . LYS A 1 233 ? 2.54300   -21.89800 -39.60600 1.000 40.07849  ? 233 LYS A CG   1 
ATOM   3589 C  CD   . LYS A 1 233 ? 3.21100   -23.02000 -38.80400 1.000 36.49911  ? 233 LYS A CD   1 
ATOM   3590 C  CE   . LYS A 1 233 ? 2.27900   -23.59100 -37.74800 1.000 41.95503  ? 233 LYS A CE   1 
ATOM   3591 N  NZ   . LYS A 1 233 ? 2.98000   -24.64900 -36.94000 1.000 40.99176  ? 233 LYS A NZ   1 
ATOM   3592 H  H    . LYS A 1 233 ? 0.61900   -22.57500 -43.02900 1.000 45.38000  ? 233 LYS A H    1 
ATOM   3593 H  HA   . LYS A 1 233 ? 0.20000   -21.02900 -40.83800 1.000 45.07000  ? 233 LYS A HA   1 
ATOM   3594 H  HB2  . LYS A 1 233 ? 1.03700   -23.09500 -40.28000 1.000 46.76000  ? 233 LYS A HB2  1 
ATOM   3595 H  HB3  . LYS A 1 233 ? 2.21900   -22.93400 -41.33100 1.000 46.76000  ? 233 LYS A HB3  1 
ATOM   3596 H  HG2  . LYS A 1 233 ? 3.23700   -21.35300 -40.00900 1.000 48.10000  ? 233 LYS A HG2  1 
ATOM   3597 H  HG3  . LYS A 1 233 ? 2.00900   -21.36200 -38.99900 1.000 48.10000  ? 233 LYS A HG3  1 
ATOM   3598 H  HD2  . LYS A 1 233 ? 3.46400   -23.73700 -39.40600 1.000 43.80000  ? 233 LYS A HD2  1 
ATOM   3599 H  HD3  . LYS A 1 233 ? 3.99700   -22.66900 -38.35700 1.000 43.80000  ? 233 LYS A HD3  1 
ATOM   3600 H  HE2  . LYS A 1 233 ? 1.99400   -22.88300 -37.15000 1.000 50.35000  ? 233 LYS A HE2  1 
ATOM   3601 H  HE3  . LYS A 1 233 ? 1.50700   -23.99100 -38.17900 1.000 50.35000  ? 233 LYS A HE3  1 
ATOM   3602 H  HZ1  . LYS A 1 233 ? 3.70200   -24.30500 -36.54900 1.000 49.19000  ? 233 LYS A HZ1  1 
ATOM   3603 H  HZ2  . LYS A 1 233 ? 2.43500   -24.96500 -36.31200 1.000 49.19000  ? 233 LYS A HZ2  1 
ATOM   3604 H  HZ3  . LYS A 1 233 ? 3.23000   -25.32000 -37.46900 1.000 49.19000  ? 233 LYS A HZ3  1 
ATOM   3605 N  N    . TYR A 1 234 ? 1.62800   -19.13000 -41.50300 1.000 39.64686  ? 234 TYR A N    1 
ATOM   3606 C  CA   . TYR A 1 234 ? 2.53900   -18.08300 -41.92700 1.000 38.77570  ? 234 TYR A CA   1 
ATOM   3607 C  C    . TYR A 1 234 ? 2.97400   -17.23000 -40.74900 1.000 38.91519  ? 234 TYR A C    1 
ATOM   3608 O  O    . TYR A 1 234 ? 2.33400   -17.19000 -39.69300 1.000 40.19429  ? 234 TYR A O    1 
ATOM   3609 C  CB   . TYR A 1 234 ? 1.91800   -17.21500 -43.03500 1.000 40.61803  ? 234 TYR A CB   1 
ATOM   3610 C  CG   . TYR A 1 234 ? 0.71500   -16.39000 -42.64200 1.000 42.62880  ? 234 TYR A CG   1 
ATOM   3611 C  CD1  . TYR A 1 234 ? 0.87000   -15.10600 -42.13200 1.000 44.47639  ? 234 TYR A CD1  1 
ATOM   3612 C  CD2  . TYR A 1 234 ? -0.57800  -16.88500 -42.79700 1.000 42.19453  ? 234 TYR A CD2  1 
ATOM   3613 C  CE1  . TYR A 1 234 ? -0.22600  -14.33900 -41.78100 1.000 45.70811  ? 234 TYR A CE1  1 
ATOM   3614 C  CE2  . TYR A 1 234 ? -1.67700  -16.12600 -42.45400 1.000 43.54206  ? 234 TYR A CE2  1 
ATOM   3615 C  CZ   . TYR A 1 234 ? -1.49700  -14.85200 -41.94500 1.000 47.99786  ? 234 TYR A CZ   1 
ATOM   3616 O  OH   . TYR A 1 234 ? -2.58900  -14.08200 -41.59500 1.000 45.55020  ? 234 TYR A OH   1 
ATOM   3617 H  H    . TYR A 1 234 ? 1.03900   -18.89300 -40.92300 1.000 47.58000  ? 234 TYR A H    1 
ATOM   3618 H  HA   . TYR A 1 234 ? 3.34500   -18.49600 -42.27500 1.000 46.53000  ? 234 TYR A HA   1 
ATOM   3619 H  HB2  . TYR A 1 234 ? 2.59600   -16.59800 -43.35200 1.000 48.74000  ? 234 TYR A HB2  1 
ATOM   3620 H  HB3  . TYR A 1 234 ? 1.63900   -17.80100 -43.75700 1.000 48.74000  ? 234 TYR A HB3  1 
ATOM   3621 H  HD1  . TYR A 1 234 ? 1.72500   -14.75600 -42.02600 1.000 53.37000  ? 234 TYR A HD1  1 
ATOM   3622 H  HD2  . TYR A 1 234 ? -0.70100  -17.74100 -43.13800 1.000 50.63000  ? 234 TYR A HD2  1 
ATOM   3623 H  HE1  . TYR A 1 234 ? -0.10700  -13.48300 -41.43700 1.000 54.85000  ? 234 TYR A HE1  1 
ATOM   3624 H  HE2  . TYR A 1 234 ? -2.53500  -16.46800 -42.56400 1.000 52.25000  ? 234 TYR A HE2  1 
ATOM   3625 H  HH   . TYR A 1 234 ? -2.33500  -13.32800 -41.32600 1.000 54.66000  ? 234 TYR A HH   1 
ATOM   3626 N  N    . LEU A 1 235 ? 4.10100   -16.55800 -40.95700 1.000 37.06760  ? 235 LEU A N    1 
ATOM   3627 C  CA   . LEU A 1 235 ? 4.72500   -15.72300 -39.94300 1.000 34.56730  ? 235 LEU A CA   1 
ATOM   3628 C  C    . LEU A 1 235 ? 4.04800   -14.36200 -39.92200 1.000 36.97285  ? 235 LEU A C    1 
ATOM   3629 O  O    . LEU A 1 235 ? 4.02500   -13.65300 -40.94000 1.000 38.25195  ? 235 LEU A O    1 
ATOM   3630 C  CB   . LEU A 1 235 ? 6.21000   -15.59300 -40.25200 1.000 34.79365  ? 235 LEU A CB   1 
ATOM   3631 C  CG   . LEU A 1 235 ? 7.06300   -14.78400 -39.29400 1.000 37.08076  ? 235 LEU A CG   1 
ATOM   3632 C  CD1  . LEU A 1 235 ? 7.01900   -15.37800 -37.91100 1.000 36.03327  ? 235 LEU A CD1  1 
ATOM   3633 C  CD2  . LEU A 1 235 ? 8.47800   -14.75000 -39.82800 1.000 33.89354  ? 235 LEU A CD2  1 
ATOM   3634 H  H    . LEU A 1 235 ? 4.53400   -16.57100 -41.69900 1.000 44.48000  ? 235 LEU A H    1 
ATOM   3635 H  HA   . LEU A 1 235 ? 4.62200   -16.12000 -39.06400 1.000 41.48000  ? 235 LEU A HA   1 
ATOM   3636 H  HB2  . LEU A 1 235 ? 6.58700   -16.48700 -40.27500 1.000 41.75000  ? 235 LEU A HB2  1 
ATOM   3637 H  HB3  . LEU A 1 235 ? 6.29500   -15.17500 -41.12300 1.000 41.75000  ? 235 LEU A HB3  1 
ATOM   3638 H  HG   . LEU A 1 235 ? 6.72700   -13.87700 -39.22100 1.000 44.50000  ? 235 LEU A HG   1 
ATOM   3639 H  HD11 . LEU A 1 235 ? 7.68900   -14.94600 -37.36000 1.000 43.24000  ? 235 LEU A HD11 1 
ATOM   3640 H  HD12 . LEU A 1 235 ? 6.13700   -15.23400 -37.53300 1.000 43.24000  ? 235 LEU A HD12 1 
ATOM   3641 H  HD13 . LEU A 1 235 ? 7.20200   -16.32900 -37.97000 1.000 43.24000  ? 235 LEU A HD13 1 
ATOM   3642 H  HD21 . LEU A 1 235 ? 9.02800   -14.21800 -39.23200 1.000 40.67000  ? 235 LEU A HD21 1 
ATOM   3643 H  HD22 . LEU A 1 235 ? 8.82000   -15.65700 -39.87300 1.000 40.67000  ? 235 LEU A HD22 1 
ATOM   3644 H  HD23 . LEU A 1 235 ? 8.47200   -14.35500 -40.71400 1.000 40.67000  ? 235 LEU A HD23 1 
ATOM   3645 N  N    . VAL A 1 236 ? 3.48700   -14.01000 -38.77000 1.000 37.54134  ? 236 VAL A N    1 
ATOM   3646 C  CA   . VAL A 1 236 ? 2.86100   -12.70500 -38.58000 1.000 41.90766  ? 236 VAL A CA   1 
ATOM   3647 C  C    . VAL A 1 236 ? 3.87600   -11.68500 -38.09000 1.000 42.37087  ? 236 VAL A C    1 
ATOM   3648 O  O    . VAL A 1 236 ? 3.90900   -10.54700 -38.56100 1.000 40.77331  ? 236 VAL A O    1 
ATOM   3649 C  CB   . VAL A 1 236 ? 1.68600   -12.83500 -37.58800 1.000 42.27612  ? 236 VAL A CB   1 
ATOM   3650 C  CG1  . VAL A 1 236 ? 1.11500   -11.45800 -37.23500 1.000 39.65475  ? 236 VAL A CG1  1 
ATOM   3651 C  CG2  . VAL A 1 236 ? 0.61800   -13.75200 -38.13300 1.000 39.94953  ? 236 VAL A CG2  1 
ATOM   3652 H  H    . VAL A 1 236 ? 3.45500   -14.51400 -38.07400 1.000 45.05000  ? 236 VAL A H    1 
ATOM   3653 H  HA   . VAL A 1 236 ? 2.51000   -12.39800 -39.43100 1.000 50.29000  ? 236 VAL A HA   1 
ATOM   3654 H  HB   . VAL A 1 236 ? 2.01800   -13.23200 -36.76800 1.000 50.73000  ? 236 VAL A HB   1 
ATOM   3655 H  HG11 . VAL A 1 236 ? 0.25600   -11.57500 -36.80000 1.000 47.58000  ? 236 VAL A HG11 1 
ATOM   3656 H  HG12 . VAL A 1 236 ? 1.73000   -11.00500 -36.63700 1.000 47.58000  ? 236 VAL A HG12 1 
ATOM   3657 H  HG13 . VAL A 1 236 ? 1.00600   -10.94300 -38.05000 1.000 47.58000  ? 236 VAL A HG13 1 
ATOM   3658 H  HG21 . VAL A 1 236 ? -0.12800  -13.77100 -37.51300 1.000 47.94000  ? 236 VAL A HG21 1 
ATOM   3659 H  HG22 . VAL A 1 236 ? 0.32400   -13.41700 -38.99500 1.000 47.94000  ? 236 VAL A HG22 1 
ATOM   3660 H  HG23 . VAL A 1 236 ? 0.98700   -14.64300 -38.23300 1.000 47.94000  ? 236 VAL A HG23 1 
ATOM   3661 N  N    . GLN A 1 237 ? 4.71800   -12.08000 -37.13900 1.000 38.51514  ? 237 GLN A N    1 
ATOM   3662 C  CA   . GLN A 1 237 ? 5.59100   -11.13000 -36.47400 1.000 38.90730  ? 237 GLN A CA   1 
ATOM   3663 C  C    . GLN A 1 237 ? 6.79100   -11.88800 -35.92500 1.000 39.13101  ? 237 GLN A C    1 
ATOM   3664 O  O    . GLN A 1 237 ? 6.64900   -12.98200 -35.37600 1.000 38.16773  ? 237 GLN A O    1 
ATOM   3665 C  CB   . GLN A 1 237 ? 4.80900   -10.39100 -35.38600 1.000 43.89474  ? 237 GLN A CB   1 
ATOM   3666 C  CG   . GLN A 1 237 ? 5.05900   -8.91800  -35.40300 1.000 55.23557  ? 237 GLN A CG   1 
ATOM   3667 C  CD   . GLN A 1 237 ? 6.16200   -8.51600  -34.46400 1.000 61.93111  ? 237 GLN A CD   1 
ATOM   3668 O  OE1  . GLN A 1 237 ? 6.20800   -8.96400  -33.31900 1.000 67.75549  ? 237 GLN A OE1  1 
ATOM   3669 N  NE2  . GLN A 1 237 ? 7.10000   -7.71700  -34.96100 1.000 59.45713  ? 237 GLN A NE2  1 
ATOM   3670 H  H    . GLN A 1 237 ? 4.79900   -12.89000 -36.86400 1.000 46.22000  ? 237 GLN A H    1 
ATOM   3671 H  HA   . GLN A 1 237 ? 5.94300   -10.46800 -37.08900 1.000 46.69000  ? 237 GLN A HA   1 
ATOM   3672 H  HB2  . GLN A 1 237 ? 3.86000   -10.53700 -35.52300 1.000 52.67000  ? 237 GLN A HB2  1 
ATOM   3673 H  HB3  . GLN A 1 237 ? 5.07600   -10.73200 -34.51800 1.000 52.67000  ? 237 GLN A HB3  1 
ATOM   3674 H  HG2  . GLN A 1 237 ? 5.31300   -8.64900  -36.30000 1.000 66.28000  ? 237 GLN A HG2  1 
ATOM   3675 H  HG3  . GLN A 1 237 ? 4.25000   -8.45500  -35.13500 1.000 66.28000  ? 237 GLN A HG3  1 
ATOM   3676 H  HE21 . GLN A 1 237 ? 7.05500   -7.45900  -35.78000 1.000 71.35000  ? 237 GLN A HE21 1 
ATOM   3677 H  HE22 . GLN A 1 237 ? 7.75200   -7.45900  -34.46400 1.000 71.35000  ? 237 GLN A HE22 1 
ATOM   3678 N  N    . GLN A 1 238 ? 7.98000   -11.32500 -36.11900 1.000 38.51778  ? 238 GLN A N    1 
ATOM   3679 C  CA   . GLN A 1 238 ? 9.23900   -11.92800 -35.63000 1.000 37.63083  ? 238 GLN A CA   1 
ATOM   3680 C  C    . GLN A 1 238 ? 10.06200  -10.86200 -34.92700 1.000 40.01269  ? 238 GLN A C    1 
ATOM   3681 O  O    . GLN A 1 238 ? 10.12900  -9.77700  -35.42100 1.000 41.77869  ? 238 GLN A O    1 
ATOM   3682 C  CB   . GLN A 1 238 ? 10.05600  -12.50700 -36.78300 1.000 34.40676  ? 238 GLN A CB   1 
ATOM   3683 C  CG   . GLN A 1 238 ? 11.31100  -13.25200 -36.34400 1.000 34.28569  ? 238 GLN A CG   1 
ATOM   3684 C  CD   . GLN A 1 238 ? 10.93800  -14.46300 -35.53300 1.000 35.53058  ? 238 GLN A CD   1 
ATOM   3685 O  OE1  . GLN A 1 238 ? 9.77800   -14.83100 -35.49200 1.000 37.04392  ? 238 GLN A OE1  1 
ATOM   3686 N  NE2  . GLN A 1 238 ? 11.89400  -15.06800 -34.85700 1.000 32.42231  ? 238 GLN A NE2  1 
ATOM   3687 H  H    . GLN A 1 238 ? 8.10300   -10.53500 -36.56000 1.000 46.22000  ? 238 GLN A H    1 
ATOM   3688 H  HA   . GLN A 1 238 ? 9.02600   -12.62500 -34.98300 1.000 45.16000  ? 238 GLN A HA   1 
ATOM   3689 H  HB2  . GLN A 1 238 ? 9.48300   -13.10900 -37.30200 1.000 41.29000  ? 238 GLN A HB2  1 
ATOM   3690 H  HB3  . GLN A 1 238 ? 10.31800  -11.76900 -37.37200 1.000 41.29000  ? 238 GLN A HB3  1 
ATOM   3691 H  HG2  . GLN A 1 238 ? 11.81900  -13.53400 -37.12900 1.000 41.14000  ? 238 GLN A HG2  1 
ATOM   3692 H  HG3  . GLN A 1 238 ? 11.88200  -12.66200 -35.80800 1.000 41.14000  ? 238 GLN A HG3  1 
ATOM   3693 H  HE21 . GLN A 1 238 ? 12.72500  -15.03500 -35.14400 1.000 38.91000  ? 238 GLN A HE21 1 
ATOM   3694 H  HE22 . GLN A 1 238 ? 11.70100  -15.51000 -34.11600 1.000 38.91000  ? 238 GLN A HE22 1 
ATOM   3695 N  N    . GLU A 1 239 ? 10.60900  -11.15800 -33.76400 1.000 36.21750  ? 239 GLU A N    1 
ATOM   3696 C  CA   . GLU A 1 239 ? 11.51600  -10.23700 -33.05000 1.000 38.19668  ? 239 GLU A CA   1 
ATOM   3697 C  C    . GLU A 1 239 ? 12.68000  -11.11400 -32.60500 1.000 37.51766  ? 239 GLU A C    1 
ATOM   3698 O  O    . GLU A 1 239 ? 12.62200  -11.60200 -31.53000 1.000 34.08040  ? 239 GLU A O    1 
ATOM   3699 C  CB   . GLU A 1 239 ? 10.82300  -9.55100  -31.87700 1.000 41.14441  ? 239 GLU A CB   1 
ATOM   3700 C  CG   . GLU A 1 239 ? 9.79600   -8.51600  -32.28200 1.000 55.86196  ? 239 GLU A CG   1 
ATOM   3701 C  CD   . GLU A 1 239 ? 10.29800  -7.09100  -32.16100 1.000 60.60727  ? 239 GLU A CD   1 
ATOM   3702 O  OE1  . GLU A 1 239 ? 11.10800  -6.68600  -32.99900 1.000 62.52855  ? 239 GLU A OE1  1 
ATOM   3703 O  OE2  . GLU A 1 239 ? 9.88900   -6.40300  -31.21000 1.000 73.38511  ? 239 GLU A OE2  1 
ATOM   3704 H  H    . GLU A 1 239 ? 10.47200  -11.94700 -33.32600 1.000 43.46000  ? 239 GLU A H    1 
ATOM   3705 H  HA   . GLU A 1 239 ? 11.85100  -9.55600  -33.67400 1.000 45.84000  ? 239 GLU A HA   1 
ATOM   3706 H  HB2  . GLU A 1 239 ? 10.38100  -10.23700 -31.33300 1.000 49.37000  ? 239 GLU A HB2  1 
ATOM   3707 H  HB3  . GLU A 1 239 ? 11.50500  -9.11900  -31.32200 1.000 49.37000  ? 239 GLU A HB3  1 
ATOM   3708 H  HG2  . GLU A 1 239 ? 9.52500   -8.67100  -33.20700 1.000 67.04000  ? 239 GLU A HG2  1 
ATOM   3709 H  HG3  . GLU A 1 239 ? 9.00100   -8.61600  -31.71800 1.000 67.04000  ? 239 GLU A HG3  1 
ATOM   3710 N  N    . SER A 1 240 ? 13.67600  -11.31900 -33.44500 1.000 34.29885  ? 240 SER A N    1 
ATOM   3711 C  CA   . SER A 1 240 ? 14.81800  -12.21100 -33.15000 1.000 35.09631  ? 240 SER A CA   1 
ATOM   3712 C  C    . SER A 1 240 ? 16.01600  -11.68500 -33.91900 1.000 34.63310  ? 240 SER A C    1 
ATOM   3713 O  O    . SER A 1 240 ? 15.80800  -11.07800 -34.96000 1.000 36.20960  ? 240 SER A O    1 
ATOM   3714 C  CB   . SER A 1 240 ? 14.52700  -13.62300 -33.54400 1.000 31.67485  ? 240 SER A CB   1 
ATOM   3715 O  OG   . SER A 1 240 ? 14.30200  -13.71700 -34.93400 1.000 32.43020  ? 240 SER A OG   1 
ATOM   3716 H  H    . SER A 1 240 ? 13.73100  -10.93600 -34.26900 1.000 41.16000  ? 240 SER A H    1 
ATOM   3717 H  HA   . SER A 1 240 ? 15.01000  -12.17500 -32.17800 1.000 42.11000  ? 240 SER A HA   1 
ATOM   3718 H  HB2  . SER A 1 240 ? 15.28600  -14.19400 -33.29000 1.000 38.01000  ? 240 SER A HB2  1 
ATOM   3719 H  HB3  . SER A 1 240 ? 13.73100  -13.93900 -33.06100 1.000 38.01000  ? 240 SER A HB3  1 
ATOM   3720 H  HG   . SER A 1 240 ? 15.03100  -13.86900 -35.33400 1.000 38.91000  ? 240 SER A HG   1 
ATOM   3721 N  N    . PRO A 1 241 ? 17.24800  -11.85000 -33.42600 1.000 33.25925  ? 241 PRO A N    1 
ATOM   3722 C  CA   . PRO A 1 241 ? 18.41200  -11.45700 -34.23600 1.000 33.09344  ? 241 PRO A CA   1 
ATOM   3723 C  C    . PRO A 1 241 ? 18.79400  -12.47000 -35.30000 1.000 35.27528  ? 241 PRO A C    1 
ATOM   3724 O  O    . PRO A 1 241 ? 19.67700  -12.17900 -36.12300 1.000 33.43032  ? 241 PRO A O    1 
ATOM   3725 C  CB   . PRO A 1 241 ? 19.53100  -11.31900 -33.20400 1.000 38.53357  ? 241 PRO A CB   1 
ATOM   3726 C  CG   . PRO A 1 241 ? 19.12700  -12.24300 -32.08700 1.000 36.35699  ? 241 PRO A CG   1 
ATOM   3727 C  CD   . PRO A 1 241 ? 17.61800  -12.19800 -32.04100 1.000 36.19118  ? 241 PRO A CD   1 
ATOM   3728 H  HA   . PRO A 1 241 ? 18.25000  -10.59500 -34.65100 1.000 39.71000  ? 241 PRO A HA   1 
ATOM   3729 H  HB2  . PRO A 1 241 ? 20.37800  -11.58900 -33.59200 1.000 46.24000  ? 241 PRO A HB2  1 
ATOM   3730 H  HB3  . PRO A 1 241 ? 19.58700  -10.40100 -32.89400 1.000 46.24000  ? 241 PRO A HB3  1 
ATOM   3731 H  HG2  . PRO A 1 241 ? 19.43800  -13.14200 -32.27700 1.000 43.63000  ? 241 PRO A HG2  1 
ATOM   3732 H  HG3  . PRO A 1 241 ? 19.50600  -11.93100 -31.25000 1.000 43.63000  ? 241 PRO A HG3  1 
ATOM   3733 H  HD2  . PRO A 1 241 ? 17.25300  -13.06200 -31.79300 1.000 43.43000  ? 241 PRO A HD2  1 
ATOM   3734 H  HD3  . PRO A 1 241 ? 17.31100  -11.51800 -31.42000 1.000 43.43000  ? 241 PRO A HD3  1 
ATOM   3735 N  N    . PHE A 1 242 ? 18.17000  -13.63800 -35.28900 1.000 32.19333  ? 242 PHE A N    1 
ATOM   3736 C  CA   . PHE A 1 242 ? 18.38500  -14.68800 -36.26700 1.000 32.45915  ? 242 PHE A CA   1 
ATOM   3737 C  C    . PHE A 1 242 ? 17.15600  -15.57700 -36.22400 1.000 33.55139  ? 242 PHE A C    1 
ATOM   3738 O  O    . PHE A 1 242 ? 16.36600  -15.52300 -35.28400 1.000 31.01951  ? 242 PHE A O    1 
ATOM   3739 C  CB   . PHE A 1 242 ? 19.66000  -15.49600 -35.98300 1.000 31.55905  ? 242 PHE A CB   1 
ATOM   3740 C  CG   . PHE A 1 242 ? 19.58100  -16.35400 -34.75800 1.000 30.52208  ? 242 PHE A CG   1 
ATOM   3741 C  CD1  . PHE A 1 242 ? 19.08700  -17.64700 -34.81900 1.000 30.81159  ? 242 PHE A CD1  1 
ATOM   3742 C  CD2  . PHE A 1 242 ? 19.97900  -15.85500 -33.53300 1.000 33.39085  ? 242 PHE A CD2  1 
ATOM   3743 C  CE1  . PHE A 1 242 ? 19.00400  -18.43500 -33.66900 1.000 32.27492  ? 242 PHE A CE1  1 
ATOM   3744 C  CE2  . PHE A 1 242 ? 19.89400  -16.63400 -32.38700 1.000 30.37996  ? 242 PHE A CE2  1 
ATOM   3745 C  CZ   . PHE A 1 242 ? 19.40100  -17.91800 -32.45400 1.000 32.16965  ? 242 PHE A CZ   1 
ATOM   3746 H  H    . PHE A 1 242 ? 17.58800  -13.85700 -34.69500 1.000 38.64000  ? 242 PHE A H    1 
ATOM   3747 H  HA   . PHE A 1 242 ? 18.48500  -14.30900 -37.15400 1.000 38.95000  ? 242 PHE A HA   1 
ATOM   3748 H  HB2  . PHE A 1 242 ? 19.83400  -16.07700 -36.73900 1.000 37.87000  ? 242 PHE A HB2  1 
ATOM   3749 H  HB3  . PHE A 1 242 ? 20.39800  -14.87800 -35.86300 1.000 37.87000  ? 242 PHE A HB3  1 
ATOM   3750 H  HD1  . PHE A 1 242 ? 18.80800  -17.99400 -35.63500 1.000 36.97000  ? 242 PHE A HD1  1 
ATOM   3751 H  HD2  . PHE A 1 242 ? 20.30700  -14.98600 -33.47600 1.000 40.07000  ? 242 PHE A HD2  1 
ATOM   3752 H  HE1  . PHE A 1 242 ? 18.68200  -19.30600 -33.72200 1.000 38.73000  ? 242 PHE A HE1  1 
ATOM   3753 H  HE2  . PHE A 1 242 ? 20.17100  -16.28700 -31.57000 1.000 36.46000  ? 242 PHE A HE2  1 
ATOM   3754 H  HZ   . PHE A 1 242 ? 19.33600  -18.43400 -31.68400 1.000 38.60000  ? 242 PHE A HZ   1 
ATOM   3755 N  N    . VAL A 1 243 ? 16.97300  -16.35900 -37.28500 1.000 29.85358  ? 243 VAL A N    1 
ATOM   3756 C  CA   . VAL A 1 243 ? 16.05100  -17.48100 -37.26700 1.000 30.07466  ? 243 VAL A CA   1 
ATOM   3757 C  C    . VAL A 1 243 ? 16.76400  -18.69700 -37.83300 1.000 28.61133  ? 243 VAL A C    1 
ATOM   3758 O  O    . VAL A 1 243 ? 17.68300  -18.58600 -38.65300 1.000 30.54577  ? 243 VAL A O    1 
ATOM   3759 C  CB   . VAL A 1 243 ? 14.73700  -17.22400 -38.03100 1.000 30.66420  ? 243 VAL A CB   1 
ATOM   3760 C  CG1  . VAL A 1 243 ? 13.98600  -16.05700 -37.44600 1.000 31.71959  ? 243 VAL A CG1  1 
ATOM   3761 C  CG2  . VAL A 1 243 ? 15.00300  -16.97000 -39.51000 1.000 31.88014  ? 243 VAL A CG2  1 
ATOM   3762 H  H    . VAL A 1 243 ? 17.37900  -16.25500 -38.03600 1.000 35.82000  ? 243 VAL A H    1 
ATOM   3763 H  HA   . VAL A 1 243 ? 15.80900  -17.65100 -36.34300 1.000 36.09000  ? 243 VAL A HA   1 
ATOM   3764 H  HB   . VAL A 1 243 ? 14.18900  -18.02000 -37.94500 1.000 36.80000  ? 243 VAL A HB   1 
ATOM   3765 H  HG11 . VAL A 1 243 ? 13.14800  -15.95000 -37.92200 1.000 38.06000  ? 243 VAL A HG11 1 
ATOM   3766 H  HG12 . VAL A 1 243 ? 13.81400  -16.23000 -36.50700 1.000 38.06000  ? 243 VAL A HG12 1 
ATOM   3767 H  HG13 . VAL A 1 243 ? 14.52500  -15.25500 -37.54100 1.000 38.06000  ? 243 VAL A HG13 1 
ATOM   3768 H  HG21 . VAL A 1 243 ? 14.16700  -16.74200 -39.94600 1.000 38.26000  ? 243 VAL A HG21 1 
ATOM   3769 H  HG22 . VAL A 1 243 ? 15.63200  -16.23700 -39.59700 1.000 38.26000  ? 243 VAL A HG22 1 
ATOM   3770 H  HG23 . VAL A 1 243 ? 15.37400  -17.77400 -39.90700 1.000 38.26000  ? 243 VAL A HG23 1 
ATOM   3771 N  N    . MET A 1 244 ? 16.32600  -19.87000 -37.39900 1.000 28.61659  ? 244 MET A N    1 
ATOM   3772 C  CA   . MET A 1 244 ? 16.82500  -21.14400 -37.90600 1.000 27.94809  ? 244 MET A CA   1 
ATOM   3773 C  C    . MET A 1 244 ? 15.67500  -21.93800 -38.50800 1.000 29.67198  ? 244 MET A C    1 
ATOM   3774 O  O    . MET A 1 244 ? 14.69000  -22.23900 -37.82500 1.000 29.57197  ? 244 MET A O    1 
ATOM   3775 C  CB   . MET A 1 244 ? 17.53900  -21.91300 -36.79600 1.000 28.10600  ? 244 MET A CB   1 
ATOM   3776 C  CG   . MET A 1 244 ? 18.06900  -23.27600 -37.19900 1.000 27.20853  ? 244 MET A CG   1 
ATOM   3777 S  SD   . MET A 1 244 ? 18.63500  -24.16900 -35.74100 1.000 30.30100  ? 244 MET A SD   1 
ATOM   3778 C  CE   . MET A 1 244 ? 19.11300  -25.73000 -36.41600 1.000 30.86686  ? 244 MET A CE   1 
ATOM   3779 H  H    . MET A 1 244 ? 15.72200  -19.95800 -36.79300 1.000 34.34000  ? 244 MET A H    1 
ATOM   3780 H  HA   . MET A 1 244 ? 17.46700  -20.98600 -38.61600 1.000 33.54000  ? 244 MET A HA   1 
ATOM   3781 H  HB2  . MET A 1 244 ? 18.29500  -21.38500 -36.49400 1.000 33.72000  ? 244 MET A HB2  1 
ATOM   3782 H  HB3  . MET A 1 244 ? 16.91600  -22.04800 -36.06500 1.000 33.72000  ? 244 MET A HB3  1 
ATOM   3783 H  HG2  . MET A 1 244 ? 17.36400  -23.78800 -37.62500 1.000 32.65000  ? 244 MET A HG2  1 
ATOM   3784 H  HG3  . MET A 1 244 ? 18.81600  -23.16900 -37.81000 1.000 32.65000  ? 244 MET A HG3  1 
ATOM   3785 H  HE1  . MET A 1 244 ? 19.45900  -26.29000 -35.70300 1.000 37.04000  ? 244 MET A HE1  1 
ATOM   3786 H  HE2  . MET A 1 244 ? 18.33800  -26.15000 -36.82000 1.000 37.04000  ? 244 MET A HE2  1 
ATOM   3787 H  HE3  . MET A 1 244 ? 19.80000  -25.58700 -37.08600 1.000 37.04000  ? 244 MET A HE3  1 
ATOM   3788 N  N    . MET A 1 245 ? 15.80400  -22.25100 -39.79500 1.000 26.34526  ? 245 MET A N    1 
ATOM   3789 C  CA   . MET A 1 245 ? 14.83400  -23.01600 -40.55600 1.000 29.26404  ? 245 MET A CA   1 
ATOM   3790 C  C    . MET A 1 245 ? 15.43600  -24.38000 -40.86100 1.000 29.96149  ? 245 MET A C    1 
ATOM   3791 O  O    . MET A 1 245 ? 16.56400  -24.46900 -41.35700 1.000 29.80094  ? 245 MET A O    1 
ATOM   3792 C  CB   . MET A 1 245 ? 14.50600  -22.27800 -41.84100 1.000 27.57962  ? 245 MET A CB   1 
ATOM   3793 C  CG   . MET A 1 245 ? 14.07100  -20.82500 -41.72300 1.000 29.76409  ? 245 MET A CG   1 
ATOM   3794 S  SD   . MET A 1 245 ? 12.58500  -20.50200 -40.76900 1.000 31.42482  ? 245 MET A SD   1 
ATOM   3795 C  CE   . MET A 1 245 ? 11.42400  -21.55600 -41.44600 1.000 32.37493  ? 245 MET A CE   1 
ATOM   3796 H  H    . MET A 1 245 ? 16.48300  -22.01700 -40.27000 1.000 31.61000  ? 245 MET A H    1 
ATOM   3797 H  HA   . MET A 1 245 ? 14.01400  -23.13700 -40.05200 1.000 35.12000  ? 245 MET A HA   1 
ATOM   3798 H  HB2  . MET A 1 245 ? 15.29800  -22.28900 -42.40100 1.000 33.10000  ? 245 MET A HB2  1 
ATOM   3799 H  HB3  . MET A 1 245 ? 13.78300  -22.75200 -42.28000 1.000 33.10000  ? 245 MET A HB3  1 
ATOM   3800 H  HG2  . MET A 1 245 ? 14.79000  -20.32800 -41.30300 1.000 35.71000  ? 245 MET A HG2  1 
ATOM   3801 H  HG3  . MET A 1 245 ? 13.91200  -20.48500 -42.61800 1.000 35.71000  ? 245 MET A HG3  1 
ATOM   3802 H  HE1  . MET A 1 245 ? 10.59000  -21.46100 -40.96100 1.000 38.85000  ? 245 MET A HE1  1 
ATOM   3803 H  HE2  . MET A 1 245 ? 11.29300  -21.32300 -42.37900 1.000 38.85000  ? 245 MET A HE2  1 
ATOM   3804 H  HE3  . MET A 1 245 ? 11.74700  -22.46800 -41.37500 1.000 38.85000  ? 245 MET A HE3  1 
ATOM   3805 N  N    . SER A 1 246 ? 14.69300  -25.44800 -40.54700 1.000 27.01903  ? 246 SER A N    1 
ATOM   3806 C  CA   . SER A 1 246 ? 15.19400  -26.80900 -40.70000 1.000 26.89796  ? 246 SER A CA   1 
ATOM   3807 C  C    . SER A 1 246 ? 14.18400  -27.67500 -41.43500 1.000 30.18257  ? 246 SER A C    1 
ATOM   3808 O  O    . SER A 1 246 ? 12.97900  -27.42200 -41.40800 1.000 29.56144  ? 246 SER A O    1 
ATOM   3809 C  CB   . SER A 1 246 ? 15.50100  -27.45500 -39.33100 1.000 31.69591  ? 246 SER A CB   1 
ATOM   3810 O  OG   . SER A 1 246 ? 16.39300  -26.65200 -38.58100 1.000 30.06150  ? 246 SER A OG   1 
ATOM   3811 H  H    . SER A 1 246 ? 13.89100  -25.40400 -40.24200 1.000 32.43000  ? 246 SER A H    1 
ATOM   3812 H  HA   . SER A 1 246 ? 16.00600  -26.78000 -41.23000 1.000 32.28000  ? 246 SER A HA   1 
ATOM   3813 H  HB2  . SER A 1 246 ? 14.67200  -27.55300 -38.83600 1.000 38.04000  ? 246 SER A HB2  1 
ATOM   3814 H  HB3  . SER A 1 246 ? 15.90500  -28.32500 -39.47600 1.000 38.04000  ? 246 SER A HB3  1 
ATOM   3815 H  HG   . SER A 1 246 ? 17.12200  -26.57200 -38.99100 1.000 36.07000  ? 246 SER A HG   1 
ATOM   3816 N  N    . ALA A 1 247 ? 14.69400  -28.71700 -42.07900 1.000 28.15864  ? 247 ALA A N    1 
ATOM   3817 C  CA   . ALA A 1 247 ? 13.85900  -29.65400 -42.80500 1.000 27.28222  ? 247 ALA A CA   1 
ATOM   3818 C  C    . ALA A 1 247 ? 14.66500  -30.91800 -43.03400 1.000 30.59051  ? 247 ALA A C    1 
ATOM   3819 O  O    . ALA A 1 247 ? 15.90400  -30.86800 -43.10300 1.000 30.94845  ? 247 ALA A O    1 
ATOM   3820 C  CB   . ALA A 1 247 ? 13.39500  -29.05900 -44.14900 1.000 30.47734  ? 247 ALA A CB   1 
ATOM   3821 H  H    . ALA A 1 247 ? 15.53300  -28.90200 -42.10900 1.000 33.79000  ? 247 ALA A H    1 
ATOM   3822 H  HA   . ALA A 1 247 ? 13.07500  -29.87600 -42.27900 1.000 32.74000  ? 247 ALA A HA   1 
ATOM   3823 H  HB1  . ALA A 1 247 ? 12.83300  -29.70500 -44.60300 1.000 36.57000  ? 247 ALA A HB1  1 
ATOM   3824 H  HB2  . ALA A 1 247 ? 12.89400  -28.24600 -43.97700 1.000 36.57000  ? 247 ALA A HB2  1 
ATOM   3825 H  HB3  . ALA A 1 247 ? 14.17400  -28.85800 -44.69100 1.000 36.57000  ? 247 ALA A HB3  1 
ATOM   3826 N  N    . PRO A 1 248 ? 14.00500  -32.05400 -43.21600 1.000 31.57221  ? 248 PRO A N    1 
ATOM   3827 C  CA   . PRO A 1 248 ? 14.73300  -33.26100 -43.63600 1.000 28.99295  ? 248 PRO A CA   1 
ATOM   3828 C  C    . PRO A 1 248 ? 15.56900  -32.95800 -44.86500 1.000 32.09595  ? 248 PRO A C    1 
ATOM   3829 O  O    . PRO A 1 248 ? 15.10000  -32.24800 -45.76900 1.000 32.89868  ? 248 PRO A O    1 
ATOM   3830 C  CB   . PRO A 1 248 ? 13.61300  -34.26600 -43.94700 1.000 35.30160  ? 248 PRO A CB   1 
ATOM   3831 C  CG   . PRO A 1 248 ? 12.43900  -33.77700 -43.12000 1.000 34.28043  ? 248 PRO A CG   1 
ATOM   3832 C  CD   . PRO A 1 248 ? 12.54500  -32.26900 -43.20100 1.000 33.17503  ? 248 PRO A CD   1 
ATOM   3833 H  HA   . PRO A 1 248 ? 15.29100  -33.61200 -42.92400 1.000 34.79000  ? 248 PRO A HA   1 
ATOM   3834 H  HB2  . PRO A 1 248 ? 13.40500  -34.25200 -44.89400 1.000 42.37000  ? 248 PRO A HB2  1 
ATOM   3835 H  HB3  . PRO A 1 248 ? 13.88200  -35.15900 -43.68000 1.000 42.37000  ? 248 PRO A HB3  1 
ATOM   3836 H  HG2  . PRO A 1 248 ? 11.60500  -34.09200 -43.50200 1.000 41.14000  ? 248 PRO A HG2  1 
ATOM   3837 H  HG3  . PRO A 1 248 ? 12.52100  -34.08600 -42.20400 1.000 41.14000  ? 248 PRO A HG3  1 
ATOM   3838 H  HD2  . PRO A 1 248 ? 12.13500  -31.93400 -44.01500 1.000 39.81000  ? 248 PRO A HD2  1 
ATOM   3839 H  HD3  . PRO A 1 248 ? 12.13800  -31.84800 -42.42800 1.000 39.81000  ? 248 PRO A HD3  1 
ATOM   3840 N  N    . PRO A 1 249 ? 16.80200  -33.46500 -44.93500 1.000 32.48284  ? 249 PRO A N    1 
ATOM   3841 C  CA   . PRO A 1 249 ? 17.70100  -33.05400 -46.02300 1.000 30.18257  ? 249 PRO A CA   1 
ATOM   3842 C  C    . PRO A 1 249 ? 17.08600  -33.34800 -47.38100 1.000 33.49349  ? 249 PRO A C    1 
ATOM   3843 O  O    . PRO A 1 249 ? 16.52900  -34.42400 -47.62300 1.000 33.43822  ? 249 PRO A O    1 
ATOM   3844 C  CB   . PRO A 1 249 ? 18.97300  -33.88000 -45.78700 1.000 31.93541  ? 249 PRO A CB   1 
ATOM   3845 C  CG   . PRO A 1 249 ? 18.63000  -34.90100 -44.77100 1.000 36.44648  ? 249 PRO A CG   1 
ATOM   3846 C  CD   . PRO A 1 249 ? 17.42800  -34.44100 -44.02900 1.000 33.05396  ? 249 PRO A CD   1 
ATOM   3847 H  HA   . PRO A 1 249 ? 17.91200  -32.11000 -45.94900 1.000 36.22000  ? 249 PRO A HA   1 
ATOM   3848 H  HB2  . PRO A 1 249 ? 19.24300  -34.30200 -46.61800 1.000 38.32000  ? 249 PRO A HB2  1 
ATOM   3849 H  HB3  . PRO A 1 249 ? 19.68000  -33.30000 -45.46400 1.000 38.32000  ? 249 PRO A HB3  1 
ATOM   3850 H  HG2  . PRO A 1 249 ? 18.44600  -35.74200 -45.21700 1.000 43.74000  ? 249 PRO A HG2  1 
ATOM   3851 H  HG3  . PRO A 1 249 ? 19.37800  -35.00500 -44.16300 1.000 43.74000  ? 249 PRO A HG3  1 
ATOM   3852 H  HD2  . PRO A 1 249 ? 16.82700  -35.18300 -43.85700 1.000 39.66000  ? 249 PRO A HD2  1 
ATOM   3853 H  HD3  . PRO A 1 249 ? 17.68200  -34.02000 -43.19300 1.000 39.66000  ? 249 PRO A HD3  1 
ATOM   3854 N  N    . ALA A 1 250 ? 17.16800  -32.35700 -48.25900 1.000 29.16929  ? 250 ALA A N    1 
ATOM   3855 C  CA   . ALA A 1 250 ? 16.66600  -32.46300 -49.61900 1.000 29.45880  ? 250 ALA A CA   1 
ATOM   3856 C  C    . ALA A 1 250 ? 17.53200  -31.56000 -50.47300 1.000 31.92488  ? 250 ALA A C    1 
ATOM   3857 O  O    . ALA A 1 250 ? 18.07200  -30.56200 -49.98700 1.000 31.74065  ? 250 ALA A O    1 
ATOM   3858 C  CB   . ALA A 1 250 ? 15.19500  -32.06000 -49.71700 1.000 34.31990  ? 250 ALA A CB   1 
ATOM   3859 H  H    . ALA A 1 250 ? 17.52100  -31.59200 -48.08500 1.000 35.00000  ? 250 ALA A H    1 
ATOM   3860 H  HA   . ALA A 1 250 ? 16.72900  -33.37500 -49.94400 1.000 35.35000  ? 250 ALA A HA   1 
ATOM   3861 H  HB1  . ALA A 1 250 ? 14.90200  -32.15400 -50.63700 1.000 41.19000  ? 250 ALA A HB1  1 
ATOM   3862 H  HB2  . ALA A 1 250 ? 14.67000  -32.64000 -49.14200 1.000 41.19000  ? 250 ALA A HB2  1 
ATOM   3863 H  HB3  . ALA A 1 250 ? 15.10000  -31.13800 -49.43100 1.000 41.19000  ? 250 ALA A HB3  1 
ATOM   3864 N  N    . GLN A 1 251 ? 17.67900  -31.92400 -51.74500 1.000 33.28031  ? 251 GLN A N    1 
ATOM   3865 C  CA   . GLN A 1 251 ? 18.37400  -31.04800 -52.67700 1.000 35.02788  ? 251 GLN A CA   1 
ATOM   3866 C  C    . GLN A 1 251 ? 17.75100  -29.65900 -52.64000 1.000 34.43044  ? 251 GLN A C    1 
ATOM   3867 O  O    . GLN A 1 251 ? 16.53200  -29.50400 -52.78000 1.000 33.82774  ? 251 GLN A O    1 
ATOM   3868 C  CB   . GLN A 1 251 ? 18.29900  -31.63700 -54.08100 1.000 37.43344  ? 251 GLN A CB   1 
ATOM   3869 C  CG   . GLN A 1 251 ? 19.12500  -32.89400 -54.23100 1.000 45.63705  ? 251 GLN A CG   1 
ATOM   3870 C  CD   . GLN A 1 251 ? 20.60200  -32.63900 -53.97700 1.000 47.26883  ? 251 GLN A CD   1 
ATOM   3871 O  OE1  . GLN A 1 251 ? 21.15500  -31.65200 -54.45000 1.000 48.90586  ? 251 GLN A OE1  1 
ATOM   3872 N  NE2  . GLN A 1 251 ? 21.24100  -33.53300 -53.23200 1.000 47.84258  ? 251 GLN A NE2  1 
ATOM   3873 H  H    . GLN A 1 251 ? 17.39000  -32.65900 -52.08500 1.000 39.94000  ? 251 GLN A H    1 
ATOM   3874 H  HA   . GLN A 1 251 ? 19.31000  -30.97200 -52.43400 1.000 42.04000  ? 251 GLN A HA   1 
ATOM   3875 H  HB2  . GLN A 1 251 ? 17.37600  -31.85800 -54.28300 1.000 44.92000  ? 251 GLN A HB2  1 
ATOM   3876 H  HB3  . GLN A 1 251 ? 18.63000  -30.98200 -54.71600 1.000 44.92000  ? 251 GLN A HB3  1 
ATOM   3877 H  HG2  . GLN A 1 251 ? 18.81800  -33.55600 -53.59200 1.000 54.76000  ? 251 GLN A HG2  1 
ATOM   3878 H  HG3  . GLN A 1 251 ? 19.02800  -33.23400 -55.13400 1.000 54.76000  ? 251 GLN A HG3  1 
ATOM   3879 H  HE21 . GLN A 1 251 ? 20.81900  -34.21400 -52.92100 1.000 57.41000  ? 251 GLN A HE21 1 
ATOM   3880 H  HE22 . GLN A 1 251 ? 22.07800  -33.43000 -53.06100 1.000 57.41000  ? 251 GLN A HE22 1 
ATOM   3881 N  N    . TYR A 1 252 ? 18.59700  -28.64500 -52.48600 1.000 31.84856  ? 252 TYR A N    1 
ATOM   3882 C  CA   . TYR A 1 252 ? 18.14600  -27.29300 -52.19800 1.000 31.66695  ? 252 TYR A CA   1 
ATOM   3883 C  C    . TYR A 1 252 ? 19.21200  -26.31400 -52.65600 1.000 34.04092  ? 252 TYR A C    1 
ATOM   3884 O  O    . TYR A 1 252 ? 20.40100  -26.53600 -52.41800 1.000 36.04643  ? 252 TYR A O    1 
ATOM   3885 C  CB   . TYR A 1 252 ? 17.87400  -27.13100 -50.69200 1.000 30.20099  ? 252 TYR A CB   1 
ATOM   3886 C  CG   . TYR A 1 252 ? 17.30700  -25.80100 -50.28600 1.000 32.81183  ? 252 TYR A CG   1 
ATOM   3887 C  CD1  . TYR A 1 252 ? 15.94500  -25.56000 -50.36700 1.000 35.75955  ? 252 TYR A CD1  1 
ATOM   3888 C  CD2  . TYR A 1 252 ? 18.12100  -24.78700 -49.80100 1.000 31.93541  ? 252 TYR A CD2  1 
ATOM   3889 C  CE1  . TYR A 1 252 ? 15.40700  -24.34300 -49.99900 1.000 36.37541  ? 252 TYR A CE1  1 
ATOM   3890 C  CE2  . TYR A 1 252 ? 17.58400  -23.55600 -49.42500 1.000 32.37493  ? 252 TYR A CE2  1 
ATOM   3891 C  CZ   . TYR A 1 252 ? 16.22600  -23.35500 -49.51800 1.000 33.62508  ? 252 TYR A CZ   1 
ATOM   3892 O  OH   . TYR A 1 252 ? 15.64700  -22.15900 -49.16500 1.000 37.61240  ? 252 TYR A OH   1 
ATOM   3893 H  H    . TYR A 1 252 ? 19.45200  -28.71800 -52.54500 1.000 38.22000  ? 252 TYR A H    1 
ATOM   3894 H  HA   . TYR A 1 252 ? 17.33100  -27.09700 -52.68700 1.000 38.00000  ? 252 TYR A HA   1 
ATOM   3895 H  HB2  . TYR A 1 252 ? 17.24000  -27.81200 -50.41900 1.000 36.24000  ? 252 TYR A HB2  1 
ATOM   3896 H  HB3  . TYR A 1 252 ? 18.71100  -27.24700 -50.21500 1.000 36.24000  ? 252 TYR A HB3  1 
ATOM   3897 H  HD1  . TYR A 1 252 ? 15.38200  -26.23200 -50.67600 1.000 42.91000  ? 252 TYR A HD1  1 
ATOM   3898 H  HD2  . TYR A 1 252 ? 19.03600  -24.93000 -49.72500 1.000 38.32000  ? 252 TYR A HD2  1 
ATOM   3899 H  HE1  . TYR A 1 252 ? 14.49300  -24.19500 -50.07600 1.000 43.65000  ? 252 TYR A HE1  1 
ATOM   3900 H  HE2  . TYR A 1 252 ? 18.13900  -22.87800 -49.11300 1.000 38.85000  ? 252 TYR A HE2  1 
ATOM   3901 H  HH   . TYR A 1 252 ? 16.23300  -21.63100 -48.87400 1.000 45.14000  ? 252 TYR A HH   1 
ATOM   3902 N  N    . GLU A 1 253 ? 18.78700  -25.24100 -53.31900 1.000 35.78850  ? 253 GLU A N    1 
ATOM   3903 C  CA   . GLU A 1 253 ? 19.73100  -24.24800 -53.81200 1.000 35.86219  ? 253 GLU A CA   1 
ATOM   3904 C  C    . GLU A 1 253 ? 19.88000  -23.12000 -52.79800 1.000 37.67820  ? 253 GLU A C    1 
ATOM   3905 O  O    . GLU A 1 253 ? 18.89000  -22.49300 -52.39600 1.000 37.53345  ? 253 GLU A O    1 
ATOM   3906 C  CB   . GLU A 1 253 ? 19.27800  -23.69400 -55.16300 1.000 41.40496  ? 253 GLU A CB   1 
ATOM   3907 C  CG   . GLU A 1 253 ? 19.93100  -22.36700 -55.48700 1.000 50.50079  ? 253 GLU A CG   1 
ATOM   3908 C  CD   . GLU A 1 253 ? 19.94900  -22.08000 -56.95900 1.000 59.11235  ? 253 GLU A CD   1 
ATOM   3909 O  OE1  . GLU A 1 253 ? 18.85100  -21.98100 -57.54800 1.000 54.18808  ? 253 GLU A OE1  1 
ATOM   3910 O  OE2  . GLU A 1 253 ? 21.06300  -21.94400 -57.51500 1.000 58.00959  ? 253 GLU A OE2  1 
ATOM   3911 H  H    . GLU A 1 253 ? 17.96300  -25.06900 -53.49200 1.000 42.95000  ? 253 GLU A H    1 
ATOM   3912 H  HA   . GLU A 1 253 ? 20.59700  -24.67100 -53.92500 1.000 43.03000  ? 253 GLU A HA   1 
ATOM   3913 H  HB2  . GLU A 1 253 ? 19.51300  -24.32500 -55.86100 1.000 49.69000  ? 253 GLU A HB2  1 
ATOM   3914 H  HB3  . GLU A 1 253 ? 18.31700  -23.56200 -55.14600 1.000 49.69000  ? 253 GLU A HB3  1 
ATOM   3915 H  HG2  . GLU A 1 253 ? 19.44000  -21.65600 -55.04700 1.000 60.60000  ? 253 GLU A HG2  1 
ATOM   3916 H  HG3  . GLU A 1 253 ? 20.84900  -22.38000 -55.17200 1.000 60.60000  ? 253 GLU A HG3  1 
ATOM   3917 N  N    . LEU A 1 254 ? 21.11900  -22.86700 -52.39300 1.000 33.83300  ? 254 LEU A N    1 
ATOM   3918 C  CA   . LEU A 1 254 ? 21.47000  -21.76400 -51.51100 1.000 35.20159  ? 254 LEU A CA   1 
ATOM   3919 C  C    . LEU A 1 254 ? 21.96500  -20.59800 -52.35300 1.000 36.22013  ? 254 LEU A C    1 
ATOM   3920 O  O    . LEU A 1 254 ? 22.98500  -20.71800 -53.04000 1.000 38.66253  ? 254 LEU A O    1 
ATOM   3921 C  CB   . LEU A 1 254 ? 22.55100  -22.20600 -50.52400 1.000 34.03040  ? 254 LEU A CB   1 
ATOM   3922 C  CG   . LEU A 1 254 ? 22.12800  -23.19400 -49.42400 1.000 34.75154  ? 254 LEU A CG   1 
ATOM   3923 C  CD1  . LEU A 1 254 ? 23.34900  -23.76600 -48.74400 1.000 30.56419  ? 254 LEU A CD1  1 
ATOM   3924 C  CD2  . LEU A 1 254 ? 21.22600  -22.54600 -48.38900 1.000 34.38833  ? 254 LEU A CD2  1 
ATOM   3925 H  H    . LEU A 1 254 ? 21.79900  -23.33900 -52.62600 1.000 40.60000  ? 254 LEU A H    1 
ATOM   3926 H  HA   . LEU A 1 254 ? 20.68900  -21.47400 -51.01500 1.000 42.24000  ? 254 LEU A HA   1 
ATOM   3927 H  HB2  . LEU A 1 254 ? 23.26100  -22.63100 -51.02900 1.000 40.84000  ? 254 LEU A HB2  1 
ATOM   3928 H  HB3  . LEU A 1 254 ? 22.89000  -21.41400 -50.07800 1.000 40.84000  ? 254 LEU A HB3  1 
ATOM   3929 H  HG   . LEU A 1 254 ? 21.62300  -23.90800 -49.84400 1.000 41.70000  ? 254 LEU A HG   1 
ATOM   3930 H  HD11 . LEU A 1 254 ? 23.06500  -24.37300 -48.04300 1.000 36.68000  ? 254 LEU A HD11 1 
ATOM   3931 H  HD12 . LEU A 1 254 ? 23.88100  -24.24400 -49.40000 1.000 36.68000  ? 254 LEU A HD12 1 
ATOM   3932 H  HD13 . LEU A 1 254 ? 23.86800  -23.04100 -48.36300 1.000 36.68000  ? 254 LEU A HD13 1 
ATOM   3933 H  HD21 . LEU A 1 254 ? 20.99700  -23.20300 -47.71400 1.000 41.27000  ? 254 LEU A HD21 1 
ATOM   3934 H  HD22 . LEU A 1 254 ? 21.69700  -21.80200 -47.98100 1.000 41.27000  ? 254 LEU A HD22 1 
ATOM   3935 H  HD23 . LEU A 1 254 ? 20.42100  -22.22700 -48.82700 1.000 41.27000  ? 254 LEU A HD23 1 
ATOM   3936 N  N    . LYS A 1 255 ? 21.24600  -19.48000 -52.30500 1.000 35.82008  ? 255 LYS A N    1 
ATOM   3937 C  CA   . LYS A 1 255 ? 21.54200  -18.31700 -53.13900 1.000 37.25710  ? 255 LYS A CA   1 
ATOM   3938 C  C    . LYS A 1 255 ? 22.36600  -17.31700 -52.32900 1.000 38.69411  ? 255 LYS A C    1 
ATOM   3939 O  O    . LYS A 1 255 ? 21.95600  -16.89200 -51.23900 1.000 35.26475  ? 255 LYS A O    1 
ATOM   3940 C  CB   . LYS A 1 255 ? 20.24900  -17.68900 -53.67000 1.000 39.00468  ? 255 LYS A CB   1 
ATOM   3941 H  H    . LYS A 1 255 ? 20.56900  -19.36800 -51.78600 1.000 42.99000  ? 255 LYS A H    1 
ATOM   3942 H  HA   . LYS A 1 255 ? 22.07500  -18.58600 -53.90300 1.000 44.71000  ? 255 LYS A HA   1 
ATOM   3943 N  N    . HIS A 1 256 ? 23.53800  -16.96800 -52.85700 1.000 34.78049  ? 256 HIS A N    1 
ATOM   3944 C  CA   . HIS A 1 256 ? 24.41600  -15.99100 -52.22900 1.000 38.54410  ? 256 HIS A CA   1 
ATOM   3945 C  C    . HIS A 1 256 ? 23.67400  -14.73700 -51.79700 1.000 37.51239  ? 256 HIS A C    1 
ATOM   3946 O  O    . HIS A 1 256 ? 22.90300  -14.15600 -52.56400 1.000 37.13603  ? 256 HIS A O    1 
ATOM   3947 C  CB   . HIS A 1 256 ? 25.52700  -15.63100 -53.21500 1.000 39.10206  ? 256 HIS A CB   1 
ATOM   3948 C  CG   . HIS A 1 256 ? 26.44300  -14.54800 -52.74400 1.000 40.02585  ? 256 HIS A CG   1 
ATOM   3949 N  ND1  . HIS A 1 256 ? 26.62200  -13.37200 -53.44600 1.000 44.73694  ? 256 HIS A ND1  1 
ATOM   3950 C  CD2  . HIS A 1 256 ? 27.25800  -14.47300 -51.66800 1.000 41.69447  ? 256 HIS A CD2  1 
ATOM   3951 C  CE1  . HIS A 1 256 ? 27.49400  -12.61300 -52.80500 1.000 47.35831  ? 256 HIS A CE1  1 
ATOM   3952 N  NE2  . HIS A 1 256 ? 27.89100  -13.25700 -51.72200 1.000 43.57365  ? 256 HIS A NE2  1 
ATOM   3953 H  H    . HIS A 1 256 ? 23.85100  -17.28900 -53.59100 1.000 41.73000  ? 256 HIS A H    1 
ATOM   3954 H  HA   . HIS A 1 256 ? 24.79900  -16.38000 -51.42700 1.000 46.25000  ? 256 HIS A HA   1 
ATOM   3955 H  HB2  . HIS A 1 256 ? 26.06600  -16.42200 -53.37600 1.000 46.92000  ? 256 HIS A HB2  1 
ATOM   3956 H  HB3  . HIS A 1 256 ? 25.12000  -15.33200 -54.04300 1.000 46.92000  ? 256 HIS A HB3  1 
ATOM   3957 H  HD2  . HIS A 1 256 ? 27.36800  -15.12400 -51.01300 1.000 50.03000  ? 256 HIS A HD2  1 
ATOM   3958 H  HE1  . HIS A 1 256 ? 27.77800  -11.76900 -53.07100 1.000 56.83000  ? 256 HIS A HE1  1 
ATOM   3959 H  HE2  . HIS A 1 256 ? 28.45600  -12.96200 -51.14400 1.000 52.29000  ? 256 HIS A HE2  1 
ATOM   3960 N  N    . GLY A 1 257 ? 23.91700  -14.32500 -50.55300 1.000 36.13854  ? 257 GLY A N    1 
ATOM   3961 C  CA   . GLY A 1 257 ? 23.35900  -13.10300 -50.01400 1.000 38.57041  ? 257 GLY A CA   1 
ATOM   3962 C  C    . GLY A 1 257 ? 21.95100  -13.19800 -49.46800 1.000 36.92811  ? 257 GLY A C    1 
ATOM   3963 O  O    . GLY A 1 257 ? 21.40700  -12.16800 -49.05000 1.000 39.96269  ? 257 GLY A O    1 
ATOM   3964 H  H    . GLY A 1 257 ? 24.41400  -14.75100 -49.99500 1.000 43.36000  ? 257 GLY A H    1 
ATOM   3965 H  HA2  . GLY A 1 257 ? 23.93100  -12.79800 -49.29200 1.000 46.28000  ? 257 GLY A HA2  1 
ATOM   3966 H  HA3  . GLY A 1 257 ? 23.35400  -12.43400 -50.71700 1.000 46.28000  ? 257 GLY A HA3  1 
ATOM   3967 N  N    . THR A 1 258 ? 21.33000  -14.37700 -49.48900 1.000 34.27516  ? 258 THR A N    1 
ATOM   3968 C  CA   . THR A 1 258 ? 19.94800  -14.52200 -49.05900 1.000 34.73574  ? 258 THR A CA   1 
ATOM   3969 C  C    . THR A 1 258 ? 19.83200  -15.24100 -47.72700 1.000 34.13830  ? 258 THR A C    1 
ATOM   3970 O  O    . THR A 1 258 ? 18.71000  -15.44300 -47.25100 1.000 34.95419  ? 258 THR A O    1 
ATOM   3971 C  CB   . THR A 1 258 ? 19.11800  -15.30700 -50.08200 1.000 34.22516  ? 258 THR A CB   1 
ATOM   3972 O  OG1  . THR A 1 258 ? 19.63100  -16.63700 -50.19500 1.000 36.37278  ? 258 THR A OG1  1 
ATOM   3973 C  CG2  . THR A 1 258 ? 19.14900  -14.63300 -51.44400 1.000 39.51790  ? 258 THR A CG2  1 
ATOM   3974 H  H    . THR A 1 258 ? 21.69400  -15.11100 -49.75200 1.000 41.13000  ? 258 THR A H    1 
ATOM   3975 H  HA   . THR A 1 258 ? 19.57500  -13.63000 -48.98900 1.000 41.69000  ? 258 THR A HA   1 
ATOM   3976 H  HB   . THR A 1 258 ? 18.19400  -15.34000 -49.78700 1.000 41.07000  ? 258 THR A HB   1 
ATOM   3977 H  HG1  . THR A 1 258 ? 19.14700  -17.08900 -50.71200 1.000 43.65000  ? 258 THR A HG1  1 
ATOM   3978 H  HG21 . THR A 1 258 ? 18.57100  -15.10700 -52.06300 1.000 47.42000  ? 258 THR A HG21 1 
ATOM   3979 H  HG22 . THR A 1 258 ? 18.84100  -13.71600 -51.36800 1.000 47.42000  ? 258 THR A HG22 1 
ATOM   3980 H  HG23 . THR A 1 258 ? 20.05300  -14.63300 -51.79400 1.000 47.42000  ? 258 THR A HG23 1 
ATOM   3981 N  N    . PHE A 1 259 ? 20.95400  -15.64800 -47.14100 1.000 32.25650  ? 259 PHE A N    1 
ATOM   3982 C  CA   . PHE A 1 259 ? 21.00200  -16.41700 -45.90600 1.000 33.07502  ? 259 PHE A CA   1 
ATOM   3983 C  C    . PHE A 1 259 ? 22.35000  -16.14200 -45.25000 1.000 31.65380  ? 259 PHE A C    1 
ATOM   3984 O  O    . PHE A 1 259 ? 23.28000  -15.60800 -45.87500 1.000 33.63035  ? 259 PHE A O    1 
ATOM   3985 C  CB   . PHE A 1 259 ? 20.76800  -17.91200 -46.18900 1.000 33.06449  ? 259 PHE A CB   1 
ATOM   3986 C  CG   . PHE A 1 259 ? 21.93100  -18.58900 -46.84900 1.000 31.33797  ? 259 PHE A CG   1 
ATOM   3987 C  CD1  . PHE A 1 259 ? 22.17200  -18.40900 -48.20500 1.000 31.69327  ? 259 PHE A CD1  1 
ATOM   3988 C  CD2  . PHE A 1 259 ? 22.78200  -19.40400 -46.12400 1.000 31.48272  ? 259 PHE A CD2  1 
ATOM   3989 C  CE1  . PHE A 1 259 ? 23.25900  -19.02700 -48.81500 1.000 31.84592  ? 259 PHE A CE1  1 
ATOM   3990 C  CE2  . PHE A 1 259 ? 23.86600  -20.03100 -46.73100 1.000 32.56443  ? 259 PHE A CE2  1 
ATOM   3991 C  CZ   . PHE A 1 259 ? 24.10400  -19.82500 -48.08000 1.000 29.48775  ? 259 PHE A CZ   1 
ATOM   3992 H  H    . PHE A 1 259 ? 21.73800  -15.48200 -47.45500 1.000 38.71000  ? 259 PHE A H    1 
ATOM   3993 H  HA   . PHE A 1 259 ? 20.31100  -16.13500 -45.28600 1.000 39.69000  ? 259 PHE A HA   1 
ATOM   3994 H  HB2  . PHE A 1 259 ? 20.59900  -18.36600 -45.34900 1.000 39.68000  ? 259 PHE A HB2  1 
ATOM   3995 H  HB3  . PHE A 1 259 ? 20.00100  -18.00200 -46.77600 1.000 39.68000  ? 259 PHE A HB3  1 
ATOM   3996 H  HD1  . PHE A 1 259 ? 21.60300  -17.87300 -48.70900 1.000 38.03000  ? 259 PHE A HD1  1 
ATOM   3997 H  HD2  . PHE A 1 259 ? 22.62700  -19.53600 -45.21600 1.000 37.78000  ? 259 PHE A HD2  1 
ATOM   3998 H  HE1  . PHE A 1 259 ? 23.41500  -18.89900 -49.72300 1.000 38.21000  ? 259 PHE A HE1  1 
ATOM   3999 H  HE2  . PHE A 1 259 ? 24.42600  -20.58300 -46.23500 1.000 39.08000  ? 259 PHE A HE2  1 
ATOM   4000 H  HZ   . PHE A 1 259 ? 24.83600  -20.22800 -48.48800 1.000 35.39000  ? 259 PHE A HZ   1 
ATOM   4001 N  N    . THR A 1 260 ? 22.46700  -16.52000 -43.97600 1.000 28.74555  ? 260 THR A N    1 
ATOM   4002 C  CA   . THR A 1 260 ? 23.73500  -16.37400 -43.27000 1.000 27.73754  ? 260 THR A CA   1 
ATOM   4003 C  C    . THR A 1 260 ? 24.62100  -17.60000 -43.45500 1.000 28.56395  ? 260 THR A C    1 
ATOM   4004 O  O    . THR A 1 260 ? 25.75400  -17.50100 -43.94300 1.000 30.11677  ? 260 THR A O    1 
ATOM   4005 C  CB   . THR A 1 260 ? 23.47300  -16.12700 -41.77500 1.000 31.44588  ? 260 THR A CB   1 
ATOM   4006 O  OG1  . THR A 1 260 ? 22.64600  -14.96800 -41.62600 1.000 35.32002  ? 260 THR A OG1  1 
ATOM   4007 C  CG2  . THR A 1 260 ? 24.77000  -15.92300 -41.04100 1.000 33.57771  ? 260 THR A CG2  1 
ATOM   4008 H  H    . THR A 1 260 ? 21.83200  -16.86000 -43.50600 1.000 34.49000  ? 260 THR A H    1 
ATOM   4009 H  HA   . THR A 1 260 ? 24.20300  -15.60500 -43.63100 1.000 33.29000  ? 260 THR A HA   1 
ATOM   4010 H  HB   . THR A 1 260 ? 23.02500  -16.89500 -41.38600 1.000 37.74000  ? 260 THR A HB   1 
ATOM   4011 H  HG1  . THR A 1 260 ? 22.49700  -14.82300 -40.81200 1.000 42.39000  ? 260 THR A HG1  1 
ATOM   4012 H  HG21 . THR A 1 260 ? 24.59900  -15.54700 -40.16300 1.000 40.29000  ? 260 THR A HG21 1 
ATOM   4013 H  HG22 . THR A 1 260 ? 25.22800  -16.77200 -40.93500 1.000 40.29000  ? 260 THR A HG22 1 
ATOM   4014 H  HG23 . THR A 1 260 ? 25.34100  -15.31700 -41.53800 1.000 40.29000  ? 260 THR A HG23 1 
ATOM   4015 N  N    . CYS A 1 261 ? 24.14200  -18.76000 -43.02300 1.000 30.47734  ? 261 CYS A N    1 
ATOM   4016 C  CA   . CYS A 1 261 ? 24.90400  -19.99000 -43.18000 1.000 29.43774  ? 261 CYS A CA   1 
ATOM   4017 C  C    . CYS A 1 261 ? 23.92100  -21.14800 -43.11900 1.000 29.99307  ? 261 CYS A C    1 
ATOM   4018 O  O    . CYS A 1 261 ? 22.73300  -20.96800 -42.84100 1.000 30.57209  ? 261 CYS A O    1 
ATOM   4019 C  CB   . CYS A 1 261 ? 25.98900  -20.12000 -42.11900 1.000 27.86124  ? 261 CYS A CB   1 
ATOM   4020 S  SG   . CYS A 1 261 ? 25.32400  -20.09300 -40.42000 1.000 31.15900  ? 261 CYS A SG   1 
ATOM   4021 H  H    . CYS A 1 261 ? 23.38100  -18.86000 -42.63700 1.000 36.57000  ? 261 CYS A H    1 
ATOM   4022 H  HA   . CYS A 1 261 ? 25.34100  -19.99700 -44.04600 1.000 35.32000  ? 261 CYS A HA   1 
ATOM   4023 H  HB2  . CYS A 1 261 ? 26.45400  -20.96200 -42.24600 1.000 33.43000  ? 261 CYS A HB2  1 
ATOM   4024 H  HB3  . CYS A 1 261 ? 26.61000  -19.38000 -42.21000 1.000 33.43000  ? 261 CYS A HB3  1 
ATOM   4025 H  HG   . CYS A 1 261 ? 26.23600  -20.14300 -39.64200 1.000 37.39000  ? 261 CYS A HG   1 
ATOM   4026 N  N    . ALA A 1 262 ? 24.42800  -22.34100 -43.41700 1.000 30.73790  ? 262 ALA A N    1 
ATOM   4027 C  CA   . ALA A 1 262 ? 23.56600  -23.49700 -43.55000 1.000 26.72162  ? 262 ALA A CA   1 
ATOM   4028 C  C    . ALA A 1 262 ? 24.36600  -24.75400 -43.27300 1.000 27.12694  ? 262 ALA A C    1 
ATOM   4029 O  O    . ALA A 1 262 ? 25.59700  -24.76800 -43.35600 1.000 29.69830  ? 262 ALA A O    1 
ATOM   4030 C  CB   . ALA A 1 262 ? 22.96100  -23.56400 -44.95700 1.000 27.03745  ? 262 ALA A CB   1 
ATOM   4031 H  H    . ALA A 1 262 ? 25.26400  -22.50000 -43.54600 1.000 36.89000  ? 262 ALA A H    1 
ATOM   4032 H  HA   . ALA A 1 262 ? 22.85500  -23.44000 -42.89300 1.000 32.07000  ? 262 ALA A HA   1 
ATOM   4033 H  HB1  . ALA A 1 262 ? 22.37400  -24.33500 -45.01200 1.000 32.45000  ? 262 ALA A HB1  1 
ATOM   4034 H  HB2  . ALA A 1 262 ? 22.45700  -22.75200 -45.12300 1.000 32.45000  ? 262 ALA A HB2  1 
ATOM   4035 H  HB3  . ALA A 1 262 ? 23.67700  -23.64700 -45.60500 1.000 32.45000  ? 262 ALA A HB3  1 
ATOM   4036 N  N    . SER A 1 263 ? 23.63600  -25.82700 -43.00000 1.000 25.61623  ? 263 SER A N    1 
ATOM   4037 C  CA   . SER A 1 263 ? 24.20500  -27.14600 -42.78500 1.000 25.93732  ? 263 SER A CA   1 
ATOM   4038 C  C    . SER A 1 263 ? 23.69900  -28.10700 -43.84900 1.000 27.80860  ? 263 SER A C    1 
ATOM   4039 O  O    . SER A 1 263 ? 22.49700  -28.16700 -44.13000 1.000 28.17443  ? 263 SER A O    1 
ATOM   4040 C  CB   . SER A 1 263 ? 23.85300  -27.66100 -41.39500 1.000 34.74627  ? 263 SER A CB   1 
ATOM   4041 O  OG   . SER A 1 263 ? 24.57200  -26.88100 -40.44900 1.000 32.51706  ? 263 SER A OG   1 
ATOM   4042 H  H    . SER A 1 263 ? 22.77800  -25.81400 -42.93300 1.000 30.74000  ? 263 SER A H    1 
ATOM   4043 H  HA   . SER A 1 263 ? 25.17000  -27.09800 -42.86600 1.000 31.13000  ? 263 SER A HA   1 
ATOM   4044 H  HB2  . SER A 1 263 ? 22.90000  -27.56700 -41.24100 1.000 41.70000  ? 263 SER A HB2  1 
ATOM   4045 H  HB3  . SER A 1 263 ? 24.11200  -28.59300 -41.31600 1.000 41.70000  ? 263 SER A HB3  1 
ATOM   4046 H  HG   . SER A 1 263 ? 24.37300  -27.12000 -39.66900 1.000 39.02000  ? 263 SER A HG   1 
ATOM   4047 N  N    . GLU A 1 264 ? 24.62300  -28.86100 -44.40800 1.000 27.32433  ? 264 GLU A N    1 
ATOM   4048 C  CA   . GLU A 1 264 ? 24.37100  -29.84500 -45.44100 1.000 29.84832  ? 264 GLU A CA   1 
ATOM   4049 C  C    . GLU A 1 264 ? 24.62400  -31.21900 -44.85900 1.000 29.15613  ? 264 GLU A C    1 
ATOM   4050 O  O    . GLU A 1 264 ? 25.66300  -31.44200 -44.24700 1.000 30.18520  ? 264 GLU A O    1 
ATOM   4051 C  CB   . GLU A 1 264 ? 25.31500  -29.62400 -46.62600 1.000 28.94558  ? 264 GLU A CB   1 
ATOM   4052 C  CG   . GLU A 1 264 ? 25.20300  -30.66100 -47.72600 1.000 31.09057  ? 264 GLU A CG   1 
ATOM   4053 C  CD   . GLU A 1 264 ? 26.31900  -30.55900 -48.73600 1.000 35.93852  ? 264 GLU A CD   1 
ATOM   4054 O  OE1  . GLU A 1 264 ? 27.43800  -31.03100 -48.44200 1.000 32.24071  ? 264 GLU A OE1  1 
ATOM   4055 O  OE2  . GLU A 1 264 ? 26.07600  -30.02400 -49.84400 1.000 37.21236  ? 264 GLU A OE2  1 
ATOM   4056 H  H    . GLU A 1 264 ? 25.45400  -28.81800 -44.19400 1.000 32.79000  ? 264 GLU A H    1 
ATOM   4057 H  HA   . GLU A 1 264 ? 23.45400  -29.78600 -45.75400 1.000 35.82000  ? 264 GLU A HA   1 
ATOM   4058 H  HB2  . GLU A 1 264 ? 25.11900  -28.75900 -47.01900 1.000 34.73000  ? 264 GLU A HB2  1 
ATOM   4059 H  HB3  . GLU A 1 264 ? 26.22900  -29.64100 -46.30000 1.000 34.73000  ? 264 GLU A HB3  1 
ATOM   4060 H  HG2  . GLU A 1 264 ? 25.23600  -31.54600 -47.33000 1.000 37.31000  ? 264 GLU A HG2  1 
ATOM   4061 H  HG3  . GLU A 1 264 ? 24.36200  -30.53800 -48.19300 1.000 37.31000  ? 264 GLU A HG3  1 
ATOM   4062 N  N    . TYR A 1 265 ? 23.72800  -32.16500 -45.11800 1.000 29.99307  ? 265 TYR A N    1 
ATOM   4063 C  CA   . TYR A 1 265 ? 23.93100  -33.53900 -44.67800 1.000 28.47710  ? 265 TYR A CA   1 
ATOM   4064 C  C    . TYR A 1 265 ? 23.86100  -34.48800 -45.86400 1.000 31.32481  ? 265 TYR A C    1 
ATOM   4065 O  O    . TYR A 1 265 ? 22.78500  -34.70500 -46.41700 1.000 29.20350  ? 265 TYR A O    1 
ATOM   4066 C  CB   . TYR A 1 265 ? 22.89600  -33.95300 -43.63900 1.000 31.79855  ? 265 TYR A CB   1 
ATOM   4067 C  CG   . TYR A 1 265 ? 23.29500  -35.23300 -42.96300 1.000 30.48523  ? 265 TYR A CG   1 
ATOM   4068 C  CD1  . TYR A 1 265 ? 24.24500  -35.21700 -41.95900 1.000 30.21678  ? 265 TYR A CD1  1 
ATOM   4069 C  CD2  . TYR A 1 265 ? 22.77300  -36.44800 -43.34400 1.000 30.45628  ? 265 TYR A CD2  1 
ATOM   4070 C  CE1  . TYR A 1 265 ? 24.64200  -36.36600 -41.34100 1.000 30.22731  ? 265 TYR A CE1  1 
ATOM   4071 C  CE2  . TYR A 1 265 ? 23.18100  -37.62500 -42.73500 1.000 31.94067  ? 265 TYR A CE2  1 
ATOM   4072 C  CZ   . TYR A 1 265 ? 24.11500  -37.56400 -41.71800 1.000 31.36429  ? 265 TYR A CZ   1 
ATOM   4073 O  OH   . TYR A 1 265 ? 24.54400  -38.71500 -41.07400 1.000 34.60941  ? 265 TYR A OH   1 
ATOM   4074 H  H    . TYR A 1 265 ? 22.99400  -32.03400 -45.54700 1.000 35.99000  ? 265 TYR A H    1 
ATOM   4075 H  HA   . TYR A 1 265 ? 24.82100  -33.58800 -44.29500 1.000 34.17000  ? 265 TYR A HA   1 
ATOM   4076 H  HB2  . TYR A 1 265 ? 22.81900  -33.25900 -42.96600 1.000 38.16000  ? 265 TYR A HB2  1 
ATOM   4077 H  HB3  . TYR A 1 265 ? 22.03900  -34.08900 -44.07400 1.000 38.16000  ? 265 TYR A HB3  1 
ATOM   4078 H  HD1  . TYR A 1 265 ? 24.62100  -34.40700 -41.70000 1.000 36.26000  ? 265 TYR A HD1  1 
ATOM   4079 H  HD2  . TYR A 1 265 ? 22.13500  -36.48000 -44.02000 1.000 36.55000  ? 265 TYR A HD2  1 
ATOM   4080 H  HE1  . TYR A 1 265 ? 25.27500  -36.33200 -40.66000 1.000 36.27000  ? 265 TYR A HE1  1 
ATOM   4081 H  HE2  . TYR A 1 265 ? 22.83200  -38.44300 -43.00700 1.000 38.33000  ? 265 TYR A HE2  1 
ATOM   4082 H  HH   . TYR A 1 265 ? 24.12500  -39.38100 -41.36700 1.000 41.53000  ? 265 TYR A HH   1 
ATOM   4083 N  N    . THR A 1 266 ? 24.98400  -35.10200 -46.20500 1.000 31.57221  ? 266 THR A N    1 
ATOM   4084 C  CA   . THR A 1 266 ? 25.05100  -36.06100 -47.30000 1.000 32.70129  ? 266 THR A CA   1 
ATOM   4085 C  C    . THR A 1 266 ? 24.97500  -37.47300 -46.75400 1.000 35.84114  ? 266 THR A C    1 
ATOM   4086 O  O    . THR A 1 266 ? 25.68700  -37.80600 -45.80800 1.000 37.77295  ? 266 THR A O    1 
ATOM   4087 C  CB   . THR A 1 266 ? 26.34900  -35.87700 -48.07900 1.000 33.24609  ? 266 THR A CB   1 
ATOM   4088 O  OG1  . THR A 1 266 ? 26.41200  -34.52400 -48.53300 1.000 36.29383  ? 266 THR A OG1  1 
ATOM   4089 C  CG2  . THR A 1 266 ? 26.40200  -36.83500 -49.25800 1.000 38.00456  ? 266 THR A CG2  1 
ATOM   4090 H  H    . THR A 1 266 ? 25.73700  -34.97800 -45.80900 1.000 37.89000  ? 266 THR A H    1 
ATOM   4091 H  HA   . THR A 1 266 ? 24.29900  -35.92600 -47.89800 1.000 39.24000  ? 266 THR A HA   1 
ATOM   4092 H  HB   . THR A 1 266 ? 27.11600  -36.06700 -47.51700 1.000 39.90000  ? 266 THR A HB   1 
ATOM   4093 H  HG1  . THR A 1 266 ? 27.13200  -34.39300 -48.94600 1.000 43.55000  ? 266 THR A HG1  1 
ATOM   4094 H  HG21 . THR A 1 266 ? 27.11600  -36.57800 -49.86200 1.000 45.61000  ? 266 THR A HG21 1 
ATOM   4095 H  HG22 . THR A 1 266 ? 26.56600  -37.73800 -48.94400 1.000 45.61000  ? 266 THR A HG22 1 
ATOM   4096 H  HG23 . THR A 1 266 ? 25.56000  -36.81700 -49.73900 1.000 45.61000  ? 266 THR A HG23 1 
ATOM   4097 N  N    . GLY A 1 267 ? 24.12300  -38.29900 -47.35600 1.000 37.35448  ? 267 GLY A N    1 
ATOM   4098 C  CA   . GLY A 1 267 ? 23.99600  -39.69800 -46.99200 1.000 39.50737  ? 267 GLY A CA   1 
ATOM   4099 C  C    . GLY A 1 267 ? 22.63200  -39.99900 -46.39000 1.000 38.64148  ? 267 GLY A C    1 
ATOM   4100 O  O    . GLY A 1 267 ? 21.74200  -39.15100 -46.31800 1.000 43.83157  ? 267 GLY A O    1 
ATOM   4101 H  H    . GLY A 1 267 ? 23.59700  -38.06200 -47.99300 1.000 44.83000  ? 267 GLY A H    1 
ATOM   4102 H  HA2  . GLY A 1 267 ? 24.11300  -40.25000 -47.78000 1.000 47.41000  ? 267 GLY A HA2  1 
ATOM   4103 H  HA3  . GLY A 1 267 ? 24.67700  -39.92700 -46.34100 1.000 47.41000  ? 267 GLY A HA3  1 
ATOM   4104 N  N    . ASN A 1 268 ? 22.48500  -41.24400 -45.95800 1.000 42.37087  ? 268 ASN A N    1 
ATOM   4105 C  CA   . ASN A 1 268 ? 21.27800  -41.65200 -45.26500 1.000 50.15338  ? 268 ASN A CA   1 
ATOM   4106 C  C    . ASN A 1 268 ? 21.37000  -41.28600 -43.79000 1.000 41.24968  ? 268 ASN A C    1 
ATOM   4107 O  O    . ASN A 1 268 ? 22.43800  -40.96900 -43.27000 1.000 45.44492  ? 268 ASN A O    1 
ATOM   4108 C  CB   . ASN A 1 268 ? 21.04600  -43.15100 -45.41400 1.000 59.46502  ? 268 ASN A CB   1 
ATOM   4109 C  CG   . ASN A 1 268 ? 20.32600  -43.49900 -46.70500 1.000 83.18629  ? 268 ASN A CG   1 
ATOM   4110 O  OD1  . ASN A 1 268 ? 20.91600  -43.47700 -47.78700 1.000 67.21595  ? 268 ASN A OD1  1 
ATOM   4111 N  ND2  . ASN A 1 268 ? 19.03500  -43.80300 -46.59700 1.000 96.81950  ? 268 ASN A ND2  1 
ATOM   4112 H  H    . ASN A 1 268 ? 23.07000  -41.86700 -46.05400 1.000 50.85000  ? 268 ASN A H    1 
ATOM   4113 H  HA   . ASN A 1 268 ? 20.52000  -41.19100 -45.65700 1.000 60.19000  ? 268 ASN A HA   1 
ATOM   4114 H  HB2  . ASN A 1 268 ? 21.90200  -43.60600 -45.41400 1.000 71.36000  ? 268 ASN A HB2  1 
ATOM   4115 H  HB3  . ASN A 1 268 ? 20.50300  -43.46300 -44.67300 1.000 71.36000  ? 268 ASN A HB3  1 
ATOM   4116 H  HD21 . ASN A 1 268 ? 18.65500  -43.79500 -45.82600 1.000 116.18000 ? 268 ASN A HD21 1 
ATOM   4117 H  HD22 . ASN A 1 268 ? 18.58200  -44.00800 -47.29900 1.000 116.18000 ? 268 ASN A HD22 1 
ATOM   4118 N  N    . TYR A 1 269 ? 20.22200  -41.33000 -43.11600 1.000 43.24992  ? 269 TYR A N    1 
ATOM   4119 C  CA   . TYR A 1 269 ? 20.17600  -41.03500 -41.69000 1.000 43.89210  ? 269 TYR A CA   1 
ATOM   4120 C  C    . TYR A 1 269 ? 21.09900  -41.96000 -40.91100 1.000 40.88911  ? 269 TYR A C    1 
ATOM   4121 O  O    . TYR A 1 269 ? 21.10000  -43.17800 -41.11100 1.000 40.77331  ? 269 TYR A O    1 
ATOM   4122 C  CB   . TYR A 1 269 ? 18.74200  -41.15900 -41.18500 1.000 45.20805  ? 269 TYR A CB   1 
ATOM   4123 C  CG   . TYR A 1 269 ? 17.81900  -40.13500 -41.80000 1.000 46.33450  ? 269 TYR A CG   1 
ATOM   4124 C  CD1  . TYR A 1 269 ? 17.86500  -38.80500 -41.39300 1.000 48.83217  ? 269 TYR A CD1  1 
ATOM   4125 C  CD2  . TYR A 1 269 ? 16.91700  -40.48800 -42.79700 1.000 46.45294  ? 269 TYR A CD2  1 
ATOM   4126 C  CE1  . TYR A 1 269 ? 17.03100  -37.85200 -41.94600 1.000 41.18652  ? 269 TYR A CE1  1 
ATOM   4127 C  CE2  . TYR A 1 269 ? 16.07900  -39.54000 -43.36500 1.000 45.95551  ? 269 TYR A CE2  1 
ATOM   4128 C  CZ   . TYR A 1 269 ? 16.14500  -38.22800 -42.93600 1.000 42.07873  ? 269 TYR A CZ   1 
ATOM   4129 O  OH   . TYR A 1 269 ? 15.32500  -37.26500 -43.47700 1.000 45.19489  ? 269 TYR A OH   1 
ATOM   4130 H  H    . TYR A 1 269 ? 19.46000  -41.52700 -43.46100 1.000 51.90000  ? 269 TYR A H    1 
ATOM   4131 H  HA   . TYR A 1 269 ? 20.47700  -40.12600 -41.54100 1.000 52.67000  ? 269 TYR A HA   1 
ATOM   4132 H  HB2  . TYR A 1 269 ? 18.40400  -42.04100 -41.40600 1.000 54.25000  ? 269 TYR A HB2  1 
ATOM   4133 H  HB3  . TYR A 1 269 ? 18.73400  -41.03200 -40.22300 1.000 54.25000  ? 269 TYR A HB3  1 
ATOM   4134 H  HD1  . TYR A 1 269 ? 18.47100  -38.55200 -40.73500 1.000 58.60000  ? 269 TYR A HD1  1 
ATOM   4135 H  HD2  . TYR A 1 269 ? 16.87500  -41.37000 -43.08700 1.000 55.74000  ? 269 TYR A HD2  1 
ATOM   4136 H  HE1  . TYR A 1 269 ? 17.06700  -36.96900 -41.65600 1.000 49.42000  ? 269 TYR A HE1  1 
ATOM   4137 H  HE2  . TYR A 1 269 ? 15.47800  -39.78600 -44.03100 1.000 55.14000  ? 269 TYR A HE2  1 
ATOM   4138 H  HH   . TYR A 1 269 ? 14.85700  -37.59700 -44.09000 1.000 54.23000  ? 269 TYR A HH   1 
ATOM   4139 N  N    . GLN A 1 270 ? 21.88800  -41.36400 -40.01800 1.000 40.36800  ? 270 GLN A N    1 
ATOM   4140 C  CA   . GLN A 1 270 ? 22.84900  -42.07400 -39.18000 1.000 37.77295  ? 270 GLN A CA   1 
ATOM   4141 C  C    . GLN A 1 270 ? 23.95100  -42.75400 -39.97600 1.000 42.52352  ? 270 GLN A C    1 
ATOM   4142 O  O    . GLN A 1 270 ? 24.60600  -43.66700 -39.47200 1.000 38.65463  ? 270 GLN A O    1 
ATOM   4143 C  CB   . GLN A 1 270 ? 22.16500  -43.11400 -38.29200 1.000 43.64734  ? 270 GLN A CB   1 
ATOM   4144 C  CG   . GLN A 1 270 ? 21.05800  -42.56300 -37.42500 1.000 48.39528  ? 270 GLN A CG   1 
ATOM   4145 C  CD   . GLN A 1 270 ? 20.52200  -43.61800 -36.49100 1.000 45.99499  ? 270 GLN A CD   1 
ATOM   4146 O  OE1  . GLN A 1 270 ? 19.77700  -44.50200 -36.91500 1.000 49.43487  ? 270 GLN A OE1  1 
ATOM   4147 N  NE2  . GLN A 1 270 ? 20.87300  -43.52500 -35.21000 1.000 45.30280  ? 270 GLN A NE2  1 
ATOM   4148 H  H    . GLN A 1 270 ? 21.88300  -40.51600 -39.87500 1.000 48.44000  ? 270 GLN A H    1 
ATOM   4149 H  HA   . GLN A 1 270 ? 23.26700  -41.40700 -38.61300 1.000 45.33000  ? 270 GLN A HA   1 
ATOM   4150 H  HB2  . GLN A 1 270 ? 21.77900  -43.80000 -38.86000 1.000 52.38000  ? 270 GLN A HB2  1 
ATOM   4151 H  HB3  . GLN A 1 270 ? 22.83000  -43.50600 -37.70500 1.000 52.38000  ? 270 GLN A HB3  1 
ATOM   4152 H  HG2  . GLN A 1 270 ? 21.40000  -41.82700 -36.89400 1.000 58.07000  ? 270 GLN A HG2  1 
ATOM   4153 H  HG3  . GLN A 1 270 ? 20.33100  -42.25400 -37.98900 1.000 58.07000  ? 270 GLN A HG3  1 
ATOM   4154 H  HE21 . GLN A 1 270 ? 21.38400  -42.88300 -34.95000 1.000 54.36000  ? 270 GLN A HE21 1 
ATOM   4155 H  HE22 . GLN A 1 270 ? 20.59000  -44.10600 -34.64300 1.000 54.36000  ? 270 GLN A HE22 1 
ATOM   4156 N  N    . CYS A 1 271 ? 24.18000  -42.32800 -41.21100 1.000 40.32326  ? 271 CYS A N    1 
ATOM   4157 C  CA   . CYS A 1 271 ? 25.31400  -42.83400 -41.97700 1.000 40.08112  ? 271 CYS A CA   1 
ATOM   4158 C  C    . CYS A 1 271 ? 25.66600  -41.82900 -43.06200 1.000 38.97046  ? 271 CYS A C    1 
ATOM   4159 O  O    . CYS A 1 271 ? 25.78400  -42.18500 -44.23800 1.000 43.77893  ? 271 CYS A O    1 
ATOM   4160 C  CB   . CYS A 1 271 ? 25.01700  -44.22100 -42.54200 1.000 48.69005  ? 271 CYS A CB   1 
ATOM   4161 S  SG   . CYS A 1 271 ? 23.45000  -44.39400 -43.42200 1.000 62.06797  ? 271 CYS A SG   1 
ATOM   4162 H  H    . CYS A 1 271 ? 23.69800  -41.75000 -41.62700 1.000 48.39000  ? 271 CYS A H    1 
ATOM   4163 H  HA   . CYS A 1 271 ? 26.09000  -42.94600 -41.40600 1.000 48.10000  ? 271 CYS A HA   1 
ATOM   4164 H  HB2  . CYS A 1 271 ? 25.72400  -44.45300 -43.16500 1.000 58.43000  ? 271 CYS A HB2  1 
ATOM   4165 H  HB3  . CYS A 1 271 ? 25.00400  -44.85300 -41.80500 1.000 58.43000  ? 271 CYS A HB3  1 
ATOM   4166 H  HG   . CYS A 1 271 ? 23.35700  -45.51500 -43.83900 1.000 74.48000  ? 271 CYS A HG   1 
ATOM   4167 N  N    . GLY A 1 272 ? 25.86200  -40.57700 -42.65800 1.000 37.18341  ? 272 GLY A N    1 
ATOM   4168 C  CA   . GLY A 1 272 ? 26.24200  -39.49700 -43.54700 1.000 35.76218  ? 272 GLY A CA   1 
ATOM   4169 C  C    . GLY A 1 272 ? 27.28800  -38.58800 -42.92700 1.000 31.50904  ? 272 GLY A C    1 
ATOM   4170 O  O    . GLY A 1 272 ? 28.08100  -39.03000 -42.09700 1.000 34.81470  ? 272 GLY A O    1 
ATOM   4171 H  H    . GLY A 1 272 ? 25.77600  -40.32200 -41.84100 1.000 44.62000  ? 272 GLY A H    1 
ATOM   4172 H  HA2  . GLY A 1 272 ? 26.60500  -39.86700 -44.36700 1.000 42.91000  ? 272 GLY A HA2  1 
ATOM   4173 H  HA3  . GLY A 1 272 ? 25.46000  -38.96400 -43.75900 1.000 42.91000  ? 272 GLY A HA3  1 
ATOM   4174 N  N    . HIS A 1 273 ? 27.29400  -37.31100 -43.31600 1.000 31.54589  ? 273 HIS A N    1 
ATOM   4175 C  CA   . HIS A 1 273 ? 28.35700  -36.37800 -42.96700 1.000 30.17467  ? 273 HIS A CA   1 
ATOM   4176 C  C    . HIS A 1 273 ? 27.82800  -34.97300 -43.18500 1.000 31.38797  ? 273 HIS A C    1 
ATOM   4177 O  O    . HIS A 1 273 ? 27.11500  -34.72600 -44.16100 1.000 29.89832  ? 273 HIS A O    1 
ATOM   4178 C  CB   . HIS A 1 273 ? 29.60300  -36.63200 -43.82800 1.000 32.28282  ? 273 HIS A CB   1 
ATOM   4179 C  CG   . HIS A 1 273 ? 30.76000  -35.73400 -43.52600 1.000 30.78527  ? 273 HIS A CG   1 
ATOM   4180 N  ND1  . HIS A 1 273 ? 31.70100  -36.03200 -42.56200 1.000 30.71684  ? 273 HIS A ND1  1 
ATOM   4181 C  CD2  . HIS A 1 273 ? 31.15100  -34.56300 -44.08200 1.000 31.55115  ? 273 HIS A CD2  1 
ATOM   4182 C  CE1  . HIS A 1 273 ? 32.61000  -35.07600 -42.52300 1.000 31.51694  ? 273 HIS A CE1  1 
ATOM   4183 N  NE2  . HIS A 1 273 ? 32.30000  -34.17100 -43.43600 1.000 31.83276  ? 273 HIS A NE2  1 
ATOM   4184 H  H    . HIS A 1 273 ? 26.67500  -36.95500 -43.79500 1.000 37.86000  ? 273 HIS A H    1 
ATOM   4185 H  HA   . HIS A 1 273 ? 28.61000  -36.47300 -42.03500 1.000 36.21000  ? 273 HIS A HA   1 
ATOM   4186 H  HB2  . HIS A 1 273 ? 29.89600  -37.54500 -43.68500 1.000 38.74000  ? 273 HIS A HB2  1 
ATOM   4187 H  HB3  . HIS A 1 273 ? 29.36600  -36.50100 -44.75900 1.000 38.74000  ? 273 HIS A HB3  1 
ATOM   4188 H  HD1  . HIS A 1 273 ? 31.69600  -36.73300 -42.06400 1.000 36.86000  ? 273 HIS A HD1  1 
ATOM   4189 H  HD2  . HIS A 1 273 ? 30.72200  -34.10900 -44.77100 1.000 37.86000  ? 273 HIS A HD2  1 
ATOM   4190 H  HE1  . HIS A 1 273 ? 33.34300  -35.04400 -41.95200 1.000 37.82000  ? 273 HIS A HE1  1 
ATOM   4191 H  HE2  . HIS A 1 273 ? 32.74400  -33.45300 -43.59900 1.000 38.20000  ? 273 HIS A HE2  1 
ATOM   4192 N  N    . TYR A 1 274 ? 28.18100  -34.06400 -42.27500 1.000 29.70356  ? 274 TYR A N    1 
ATOM   4193 C  CA   . TYR A 1 274 ? 27.77100  -32.67500 -42.36800 1.000 27.60068  ? 274 TYR A CA   1 
ATOM   4194 C  C    . TYR A 1 274 ? 28.86600  -31.81800 -42.97500 1.000 29.40879  ? 274 TYR A C    1 
ATOM   4195 O  O    . TYR A 1 274 ? 30.05400  -32.03000 -42.70200 1.000 28.90347  ? 274 TYR A O    1 
ATOM   4196 C  CB   . TYR A 1 274 ? 27.45500  -32.07100 -40.98900 1.000 26.98218  ? 274 TYR A CB   1 
ATOM   4197 C  CG   . TYR A 1 274 ? 26.09600  -32.34900 -40.41600 1.000 26.59003  ? 274 TYR A CG   1 
ATOM   4198 C  CD1  . TYR A 1 274 ? 24.99900  -31.60600 -40.79100 1.000 25.82152  ? 274 TYR A CD1  1 
ATOM   4199 C  CD2  . TYR A 1 274 ? 25.92800  -33.31400 -39.42000 1.000 27.22168  ? 274 TYR A CD2  1 
ATOM   4200 C  CE1  . TYR A 1 274 ? 23.73800  -31.85200 -40.23800 1.000 26.96639  ? 274 TYR A CE1  1 
ATOM   4201 C  CE2  . TYR A 1 274 ? 24.69000  -33.55500 -38.86500 1.000 26.23736  ? 274 TYR A CE2  1 
ATOM   4202 C  CZ   . TYR A 1 274 ? 23.60200  -32.81800 -39.26700 1.000 27.87966  ? 274 TYR A CZ   1 
ATOM   4203 O  OH   . TYR A 1 274 ? 22.35900  -33.03100 -38.69400 1.000 26.23999  ? 274 TYR A OH   1 
ATOM   4204 H  H    . TYR A 1 274 ? 28.66500  -34.23600 -41.58600 1.000 35.65000  ? 274 TYR A H    1 
ATOM   4205 H  HA   . TYR A 1 274 ? 26.98000  -32.65500 -42.92900 1.000 33.12000  ? 274 TYR A HA   1 
ATOM   4206 H  HB2  . TYR A 1 274 ? 28.10400  -32.41700 -40.35600 1.000 32.38000  ? 274 TYR A HB2  1 
ATOM   4207 H  HB3  . TYR A 1 274 ? 27.54000  -31.10800 -41.05900 1.000 32.38000  ? 274 TYR A HB3  1 
ATOM   4208 H  HD1  . TYR A 1 274 ? 25.09800  -30.93100 -41.42200 1.000 30.98000  ? 274 TYR A HD1  1 
ATOM   4209 H  HD2  . TYR A 1 274 ? 26.66400  -33.80200 -39.12700 1.000 32.66000  ? 274 TYR A HD2  1 
ATOM   4210 H  HE1  . TYR A 1 274 ? 22.99800  -31.36600 -40.52300 1.000 32.36000  ? 274 TYR A HE1  1 
ATOM   4211 H  HE2  . TYR A 1 274 ? 24.59100  -34.21600 -38.21900 1.000 31.49000  ? 274 TYR A HE2  1 
ATOM   4212 H  HH   . TYR A 1 274 ? 22.39100  -33.69300 -38.17700 1.000 31.49000  ? 274 TYR A HH   1 
ATOM   4213 N  N    . LYS A 1 275 ? 28.45500  -30.83000 -43.77100 1.000 29.80884  ? 275 LYS A N    1 
ATOM   4214 C  CA   . LYS A 1 275 ? 29.30400  -29.71500 -44.14400 1.000 26.17419  ? 275 LYS A CA   1 
ATOM   4215 C  C    . LYS A 1 275 ? 28.57300  -28.41700 -43.82800 1.000 26.20051  ? 275 LYS A C    1 
ATOM   4216 O  O    . LYS A 1 275 ? 27.35100  -28.38600 -43.64900 1.000 27.36644  ? 275 LYS A O    1 
ATOM   4217 C  CB   . LYS A 1 275 ? 29.70400  -29.74300 -45.64000 1.000 25.89258  ? 275 LYS A CB   1 
ATOM   4218 C  CG   . LYS A 1 275 ? 30.42300  -30.99200 -46.09100 1.000 29.20877  ? 275 LYS A CG   1 
ATOM   4219 C  CD   . LYS A 1 275 ? 30.86900  -30.88500 -47.56200 1.000 31.94594  ? 275 LYS A CD   1 
ATOM   4220 C  CE   . LYS A 1 275 ? 31.51200  -32.19800 -47.98900 1.000 35.86219  ? 275 LYS A CE   1 
ATOM   4221 N  NZ   . LYS A 1 275 ? 31.81700  -32.29800 -49.43200 1.000 37.66504  ? 275 LYS A NZ   1 
ATOM   4222 H  H    . LYS A 1 275 ? 27.66700  -30.78800 -44.11300 1.000 35.77000  ? 275 LYS A H    1 
ATOM   4223 H  HA   . LYS A 1 275 ? 30.12400  -29.75400 -43.62600 1.000 31.41000  ? 275 LYS A HA   1 
ATOM   4224 H  HB2  . LYS A 1 275 ? 28.89800  -29.66400 -46.17300 1.000 31.07000  ? 275 LYS A HB2  1 
ATOM   4225 H  HB3  . LYS A 1 275 ? 30.29200  -28.99200 -45.81400 1.000 31.07000  ? 275 LYS A HB3  1 
ATOM   4226 H  HG2  . LYS A 1 275 ? 31.21100  -31.12500 -45.54100 1.000 35.05000  ? 275 LYS A HG2  1 
ATOM   4227 H  HG3  . LYS A 1 275 ? 29.82700  -31.75400 -46.00700 1.000 35.05000  ? 275 LYS A HG3  1 
ATOM   4228 H  HD2  . LYS A 1 275 ? 30.10100  -30.71300 -48.12800 1.000 38.34000  ? 275 LYS A HD2  1 
ATOM   4229 H  HD3  . LYS A 1 275 ? 31.51900  -30.17200 -47.65900 1.000 38.34000  ? 275 LYS A HD3  1 
ATOM   4230 H  HE2  . LYS A 1 275 ? 32.34700  -32.30300 -47.50700 1.000 43.03000  ? 275 LYS A HE2  1 
ATOM   4231 H  HE3  . LYS A 1 275 ? 30.90800  -32.92400 -47.76800 1.000 43.03000  ? 275 LYS A HE3  1 
ATOM   4232 H  HZ1  . LYS A 1 275 ? 32.38100  -31.65200 -49.67000 1.000 45.20000  ? 275 LYS A HZ1  1 
ATOM   4233 H  HZ2  . LYS A 1 275 ? 32.18900  -33.08600 -49.61100 1.000 45.20000  ? 275 LYS A HZ2  1 
ATOM   4234 H  HZ3  . LYS A 1 275 ? 31.06900  -32.21700 -49.90800 1.000 45.20000  ? 275 LYS A HZ3  1 
ATOM   4235 N  N    . HIS A 1 276 ? 29.34000  -27.33700 -43.81100 1.000 28.00336  ? 276 HIS A N    1 
ATOM   4236 C  CA   . HIS A 1 276 ? 28.85900  -26.00300 -43.49100 1.000 27.86650  ? 276 HIS A CA   1 
ATOM   4237 C  C    . HIS A 1 276 ? 29.01700  -25.09100 -44.69600 1.000 28.29023  ? 276 HIS A C    1 
ATOM   4238 O  O    . HIS A 1 276 ? 30.07500  -25.08000 -45.32600 1.000 30.46681  ? 276 HIS A O    1 
ATOM   4239 C  CB   . HIS A 1 276 ? 29.67000  -25.45600 -42.32700 1.000 29.15876  ? 276 HIS A CB   1 
ATOM   4240 C  CG   . HIS A 1 276 ? 29.25900  -24.09800 -41.88000 1.000 27.37170  ? 276 HIS A CG   1 
ATOM   4241 N  ND1  . HIS A 1 276 ? 28.28000  -23.89500 -40.93700 1.000 29.93517  ? 276 HIS A ND1  1 
ATOM   4242 C  CD2  . HIS A 1 276 ? 29.69400  -22.87000 -42.24300 1.000 27.69543  ? 276 HIS A CD2  1 
ATOM   4243 C  CE1  . HIS A 1 276 ? 28.13300  -22.59800 -40.73200 1.000 27.81123  ? 276 HIS A CE1  1 
ATOM   4244 N  NE2  . HIS A 1 276 ? 28.97100  -21.95400 -41.52100 1.000 29.97201  ? 276 HIS A NE2  1 
ATOM   4245 H  H    . HIS A 1 276 ? 30.18100  -27.35300 -43.99000 1.000 33.60000  ? 276 HIS A H    1 
ATOM   4246 H  HA   . HIS A 1 276 ? 27.91600  -26.03000 -43.26500 1.000 33.44000  ? 276 HIS A HA   1 
ATOM   4247 H  HB2  . HIS A 1 276 ? 29.57100  -26.05600 -41.57200 1.000 34.99000  ? 276 HIS A HB2  1 
ATOM   4248 H  HB3  . HIS A 1 276 ? 30.60100  -25.40800 -42.59400 1.000 34.99000  ? 276 HIS A HB3  1 
ATOM   4249 H  HD1  . HIS A 1 276 ? 27.83300  -24.51500 -40.54200 1.000 35.92000  ? 276 HIS A HD1  1 
ATOM   4250 H  HD2  . HIS A 1 276 ? 30.35900  -22.68200 -42.86600 1.000 33.23000  ? 276 HIS A HD2  1 
ATOM   4251 H  HE1  . HIS A 1 276 ? 27.53900  -22.20500 -40.13300 1.000 33.38000  ? 276 HIS A HE1  1 
ATOM   4252 N  N    . ILE A 1 277 ? 27.96800  -24.33400 -45.01700 1.000 26.78742  ? 277 ILE A N    1 
ATOM   4253 C  CA   . ILE A 1 277 ? 28.01400  -23.33500 -46.08000 1.000 27.61384  ? 277 ILE A CA   1 
ATOM   4254 C  C    . ILE A 1 277 ? 27.75100  -21.97000 -45.46400 1.000 31.41429  ? 277 ILE A C    1 
ATOM   4255 O  O    . ILE A 1 277 ? 26.76800  -21.78600 -44.73400 1.000 31.54589  ? 277 ILE A O    1 
ATOM   4256 C  CB   . ILE A 1 277 ? 27.00500  -23.64900 -47.19500 1.000 29.32194  ? 277 ILE A CB   1 
ATOM   4257 C  CG1  . ILE A 1 277 ? 27.33000  -25.01200 -47.79500 1.000 34.67521  ? 277 ILE A CG1  1 
ATOM   4258 C  CG2  . ILE A 1 277 ? 27.11900  -22.61000 -48.31600 1.000 31.14058  ? 277 ILE A CG2  1 
ATOM   4259 C  CD1  . ILE A 1 277 ? 26.45400  -26.09000 -47.30400 1.000 33.82774  ? 277 ILE A CD1  1 
ATOM   4260 H  H    . ILE A 1 277 ? 27.20500  -24.38300 -44.62300 1.000 32.15000  ? 277 ILE A H    1 
ATOM   4261 H  HA   . ILE A 1 277 ? 28.90000  -23.32100 -46.47500 1.000 33.14000  ? 277 ILE A HA   1 
ATOM   4262 H  HB   . ILE A 1 277 ? 26.11300  -23.63800 -46.81500 1.000 35.18000  ? 277 ILE A HB   1 
ATOM   4263 H  HG12 . ILE A 1 277 ? 27.22900  -24.96200 -48.75900 1.000 41.61000  ? 277 ILE A HG12 1 
ATOM   4264 H  HG13 . ILE A 1 277 ? 28.24400  -25.24400 -47.56900 1.000 41.61000  ? 277 ILE A HG13 1 
ATOM   4265 H  HG21 . ILE A 1 277 ? 26.47500  -22.82200 -49.01000 1.000 37.37000  ? 277 ILE A HG21 1 
ATOM   4266 H  HG22 . ILE A 1 277 ? 26.93400  -21.73000 -47.95200 1.000 37.37000  ? 277 ILE A HG22 1 
ATOM   4267 H  HG23 . ILE A 1 277 ? 28.01800  -22.63500 -48.68000 1.000 37.37000  ? 277 ILE A HG23 1 
ATOM   4268 H  HD11 . ILE A 1 277 ? 26.71700  -26.92500 -47.72100 1.000 40.59000  ? 277 ILE A HD11 1 
ATOM   4269 H  HD12 . ILE A 1 277 ? 26.54700  -26.15700 -46.34100 1.000 40.59000  ? 277 ILE A HD12 1 
ATOM   4270 H  HD13 . ILE A 1 277 ? 25.53600  -25.88000 -47.53400 1.000 40.59000  ? 277 ILE A HD13 1 
ATOM   4271 N  N    . THR A 1 278 ? 28.65000  -21.02200 -45.73200 1.000 28.35603  ? 278 THR A N    1 
ATOM   4272 C  CA   . THR A 1 278 ? 28.52900  -19.65900 -45.23700 1.000 30.67999  ? 278 THR A CA   1 
ATOM   4273 C  C    . THR A 1 278 ? 28.52500  -18.68600 -46.40800 1.000 30.60367  ? 278 THR A C    1 
ATOM   4274 O  O    . THR A 1 278 ? 29.32200  -18.81600 -47.34200 1.000 32.90658  ? 278 THR A O    1 
ATOM   4275 C  CB   . THR A 1 278 ? 29.65100  -19.35800 -44.22500 1.000 31.11689  ? 278 THR A CB   1 
ATOM   4276 O  OG1  . THR A 1 278 ? 29.56800  -18.00100 -43.78500 1.000 32.10122  ? 278 THR A OG1  1 
ATOM   4277 C  CG2  . THR A 1 278 ? 31.02500  -19.61800 -44.82200 1.000 32.71971  ? 278 THR A CG2  1 
ATOM   4278 H  H    . THR A 1 278 ? 29.35300  -21.15200 -46.21100 1.000 34.03000  ? 278 THR A H    1 
ATOM   4279 H  HA   . THR A 1 278 ? 27.68300  -19.53600 -44.78000 1.000 36.82000  ? 278 THR A HA   1 
ATOM   4280 H  HB   . THR A 1 278 ? 29.54500  -19.94800 -43.46300 1.000 37.34000  ? 278 THR A HB   1 
ATOM   4281 H  HG1  . THR A 1 278 ? 28.81700  -17.85700 -43.43800 1.000 38.53000  ? 278 THR A HG1  1 
ATOM   4282 H  HG21 . THR A 1 278 ? 31.71400  -19.40600 -44.17300 1.000 39.26000  ? 278 THR A HG21 1 
ATOM   4283 H  HG22 . THR A 1 278 ? 31.10600  -20.55200 -45.07300 1.000 39.26000  ? 278 THR A HG22 1 
ATOM   4284 H  HG23 . THR A 1 278 ? 31.15400  -19.06800 -45.61000 1.000 39.26000  ? 278 THR A HG23 1 
ATOM   4285 N  N    . SER A 1 279 ? 27.59700  -17.74000 -46.37800 1.000 30.54840  ? 279 SER A N    1 
ATOM   4286 C  CA   . SER A 1 279 ? 27.44400  -16.76700 -47.46200 1.000 31.61168  ? 279 SER A CA   1 
ATOM   4287 C  C    . SER A 1 279 ? 28.16100  -15.48000 -47.05900 1.000 33.75405  ? 279 SER A C    1 
ATOM   4288 O  O    . SER A 1 279 ? 27.67000  -14.72600 -46.21400 1.000 34.81996  ? 279 SER A O    1 
ATOM   4289 C  CB   . SER A 1 279 ? 25.96800  -16.49800 -47.75900 1.000 32.99343  ? 279 SER A CB   1 
ATOM   4290 O  OG   . SER A 1 279 ? 25.83400  -15.50100 -48.76800 1.000 33.78037  ? 279 SER A OG   1 
ATOM   4291 H  H    . SER A 1 279 ? 27.03500  -17.63700 -45.73400 1.000 36.66000  ? 279 SER A H    1 
ATOM   4292 H  HA   . SER A 1 279 ? 27.85700  -17.11800 -48.26600 1.000 37.93000  ? 279 SER A HA   1 
ATOM   4293 H  HB2  . SER A 1 279 ? 25.55200  -17.31800 -48.06600 1.000 39.59000  ? 279 SER A HB2  1 
ATOM   4294 H  HB3  . SER A 1 279 ? 25.53300  -16.18800 -46.94900 1.000 39.59000  ? 279 SER A HB3  1 
ATOM   4295 H  HG   . SER A 1 279 ? 26.16000  -14.77500 -48.50000 1.000 40.54000  ? 279 SER A HG   1 
ATOM   4296 N  N    . LYS A 1 280 ? 29.31700  -15.23000 -47.66900 1.000 35.52531  ? 280 LYS A N    1 
ATOM   4297 C  CA   . LYS A 1 280 ? 30.10500  -14.02600 -47.41400 1.000 36.43858  ? 280 LYS A CA   1 
ATOM   4298 C  C    . LYS A 1 280 ? 30.28300  -13.30800 -48.74500 1.000 37.39659  ? 280 LYS A C    1 
ATOM   4299 O  O    . LYS A 1 280 ? 29.29200  -13.09100 -49.44900 1.000 38.89677  ? 280 LYS A O    1 
ATOM   4300 C  CB   . LYS A 1 280 ? 31.43100  -14.38800 -46.75200 1.000 38.22827  ? 280 LYS A CB   1 
ATOM   4301 C  CG   . LYS A 1 280 ? 31.25800  -15.39200 -45.62600 1.000 38.44145  ? 280 LYS A CG   1 
ATOM   4302 C  CD   . LYS A 1 280 ? 30.66000  -14.83100 -44.33900 1.000 37.77821  ? 280 LYS A CD   1 
ATOM   4303 C  CE   . LYS A 1 280 ? 31.16500  -13.46300 -43.95700 1.000 45.71074  ? 280 LYS A CE   1 
ATOM   4304 N  NZ   . LYS A 1 280 ? 30.76900  -13.14200 -42.54900 1.000 49.76913  ? 280 LYS A NZ   1 
ATOM   4305 H  H    . LYS A 1 280 ? 29.67600  -15.75400 -48.24900 1.000 42.63000  ? 280 LYS A H    1 
ATOM   4306 H  HA   . LYS A 1 280 ? 29.66600  -13.42500 -46.79200 1.000 43.73000  ? 280 LYS A HA   1 
ATOM   4307 H  HB2  . LYS A 1 280 ? 32.02200  -14.77800 -47.41600 1.000 45.87000  ? 280 LYS A HB2  1 
ATOM   4308 H  HB3  . LYS A 1 280 ? 31.83100  -13.58600 -46.38300 1.000 45.87000  ? 280 LYS A HB3  1 
ATOM   4309 H  HG2  . LYS A 1 280 ? 30.67000  -16.09900 -45.93300 1.000 46.13000  ? 280 LYS A HG2  1 
ATOM   4310 H  HG3  . LYS A 1 280 ? 32.12900  -15.75800 -45.40400 1.000 46.13000  ? 280 LYS A HG3  1 
ATOM   4311 H  HD2  . LYS A 1 280 ? 29.69800  -14.76700 -44.44700 1.000 45.34000  ? 280 LYS A HD2  1 
ATOM   4312 H  HD3  . LYS A 1 280 ? 30.87300  -15.43400 -43.61000 1.000 45.34000  ? 280 LYS A HD3  1 
ATOM   4313 H  HE2  . LYS A 1 280 ? 32.13300  -13.44300 -44.01900 1.000 54.85000  ? 280 LYS A HE2  1 
ATOM   4314 H  HE3  . LYS A 1 280 ? 30.78100  -12.79700 -44.54700 1.000 54.85000  ? 280 LYS A HE3  1 
ATOM   4315 H  HZ1  . LYS A 1 280 ? 31.10300  -13.75000 -41.99200 1.000 59.72000  ? 280 LYS A HZ1  1 
ATOM   4316 H  HZ2  . LYS A 1 280 ? 31.08000  -12.34000 -42.32000 1.000 59.72000  ? 280 LYS A HZ2  1 
ATOM   4317 H  HZ3  . LYS A 1 280 ? 29.88200  -13.13900 -42.47500 1.000 59.72000  ? 280 LYS A HZ3  1 
ATOM   4318 N  N    . GLU A 1 281 ? 31.51600  -12.93300 -49.10800 1.000 37.50186  ? 281 GLU A N    1 
ATOM   4319 C  CA   . GLU A 1 281 ? 31.72500  -12.31400 -50.41500 1.000 38.12562  ? 281 GLU A CA   1 
ATOM   4320 C  C    . GLU A 1 281 ? 31.41700  -13.29400 -51.53900 1.000 39.45736  ? 281 GLU A C    1 
ATOM   4321 O  O    . GLU A 1 281 ? 31.16100  -12.87300 -52.67800 1.000 38.78360  ? 281 GLU A O    1 
ATOM   4322 C  CB   . GLU A 1 281 ? 33.15900  -11.78400 -50.56500 1.000 41.11019  ? 281 GLU A CB   1 
ATOM   4323 C  CG   . GLU A 1 281 ? 34.28700  -12.80900 -50.41100 1.000 45.37913  ? 281 GLU A CG   1 
ATOM   4324 C  CD   . GLU A 1 281 ? 34.76000  -12.99100 -48.96300 1.000 44.81327  ? 281 GLU A CD   1 
ATOM   4325 O  OE1  . GLU A 1 281 ? 33.98300  -12.70200 -48.02700 1.000 38.90466  ? 281 GLU A OE1  1 
ATOM   4326 O  OE2  . GLU A 1 281 ? 35.91800  -13.43800 -48.76600 1.000 42.94725  ? 281 GLU A OE2  1 
ATOM   4327 H  H    . GLU A 1 281 ? 32.22500  -13.02500 -48.62900 1.000 45.00000  ? 281 GLU A H    1 
ATOM   4328 H  HA   . GLU A 1 281 ? 31.13700  -11.54600 -50.48900 1.000 45.75000  ? 281 GLU A HA   1 
ATOM   4329 H  HB2  . GLU A 1 281 ? 33.24500  -11.39800 -51.45100 1.000 49.33000  ? 281 GLU A HB2  1 
ATOM   4330 H  HB3  . GLU A 1 281 ? 33.30000  -11.10200 -49.89000 1.000 49.33000  ? 281 GLU A HB3  1 
ATOM   4331 H  HG2  . GLU A 1 281 ? 33.97400  -13.67000 -50.73100 1.000 54.46000  ? 281 GLU A HG2  1 
ATOM   4332 H  HG3  . GLU A 1 281 ? 35.04900  -12.51700 -50.93600 1.000 54.46000  ? 281 GLU A HG3  1 
ATOM   4333 N  N    . THR A 1 282 ? 31.47400  -14.58600 -51.24200 1.000 38.40724  ? 282 THR A N    1 
ATOM   4334 C  CA   . THR A 1 282 ? 30.99600  -15.65000 -52.11100 1.000 36.42016  ? 282 THR A CA   1 
ATOM   4335 C  C    . THR A 1 282 ? 30.53300  -16.77600 -51.18400 1.000 35.25160  ? 282 THR A C    1 
ATOM   4336 O  O    . THR A 1 282 ? 30.48500  -16.61000 -49.95700 1.000 34.08040  ? 282 THR A O    1 
ATOM   4337 C  CB   . THR A 1 282 ? 32.08900  -16.06500 -53.10500 1.000 39.37577  ? 282 THR A CB   1 
ATOM   4338 O  OG1  . THR A 1 282 ? 31.54900  -16.98300 -54.06300 1.000 37.12814  ? 282 THR A OG1  1 
ATOM   4339 C  CG2  . THR A 1 282 ? 33.27200  -16.71500 -52.39300 1.000 37.50713  ? 282 THR A CG2  1 
ATOM   4340 H  H    . THR A 1 282 ? 31.80100  -14.88500 -50.50500 1.000 46.09000  ? 282 THR A H    1 
ATOM   4341 H  HA   . THR A 1 282 ? 30.24000  -15.35400 -52.64200 1.000 43.70000  ? 282 THR A HA   1 
ATOM   4342 H  HB   . THR A 1 282 ? 32.41400  -15.27200 -53.56100 1.000 47.25000  ? 282 THR A HB   1 
ATOM   4343 H  HG1  . THR A 1 282 ? 32.14600  -17.21900 -54.60400 1.000 44.55000  ? 282 THR A HG1  1 
ATOM   4344 H  HG21 . THR A 1 282 ? 33.99800  -16.86100 -53.02000 1.000 45.01000  ? 282 THR A HG21 1 
ATOM   4345 H  HG22 . THR A 1 282 ? 33.58500  -16.14000 -51.67700 1.000 45.01000  ? 282 THR A HG22 1 
ATOM   4346 H  HG23 . THR A 1 282 ? 33.00500  -17.56900 -52.01700 1.000 45.01000  ? 282 THR A HG23 1 
ATOM   4347 N  N    . LEU A 1 283 ? 30.17200  -17.91800 -51.75800 1.000 32.47495  ? 283 LEU A N    1 
ATOM   4348 C  CA   . LEU A 1 283 ? 29.73900  -19.06000 -50.95900 1.000 30.67736  ? 283 LEU A CA   1 
ATOM   4349 C  C    . LEU A 1 283 ? 30.92800  -19.94200 -50.61200 1.000 30.73526  ? 283 LEU A C    1 
ATOM   4350 O  O    . LEU A 1 283 ? 31.55600  -20.52600 -51.50700 1.000 32.93026  ? 283 LEU A O    1 
ATOM   4351 C  CB   . LEU A 1 283 ? 28.69400  -19.89000 -51.69700 1.000 30.71421  ? 283 LEU A CB   1 
ATOM   4352 C  CG   . LEU A 1 283 ? 27.38000  -19.18800 -52.00300 1.000 34.39886  ? 283 LEU A CG   1 
ATOM   4353 C  CD1  . LEU A 1 283 ? 26.53700  -20.03800 -52.94100 1.000 38.00192  ? 283 LEU A CD1  1 
ATOM   4354 C  CD2  . LEU A 1 283 ? 26.64500  -18.91300 -50.73100 1.000 38.43092  ? 283 LEU A CD2  1 
ATOM   4355 H  H    . LEU A 1 283 ? 30.16900  -18.05700 -52.60600 1.000 38.97000  ? 283 LEU A H    1 
ATOM   4356 H  HA   . LEU A 1 283 ? 29.35000  -18.71700 -50.14000 1.000 36.81000  ? 283 LEU A HA   1 
ATOM   4357 H  HB2  . LEU A 1 283 ? 29.07300  -20.17100 -52.54400 1.000 36.86000  ? 283 LEU A HB2  1 
ATOM   4358 H  HB3  . LEU A 1 283 ? 28.48500  -20.66600 -51.15400 1.000 36.86000  ? 283 LEU A HB3  1 
ATOM   4359 H  HG   . LEU A 1 283 ? 27.55400  -18.34200 -52.44300 1.000 41.28000  ? 283 LEU A HG   1 
ATOM   4360 H  HD11 . LEU A 1 283 ? 25.76600  -19.52400 -53.22600 1.000 45.60000  ? 283 LEU A HD11 1 
ATOM   4361 H  HD12 . LEU A 1 283 ? 27.07300  -20.28500 -53.71000 1.000 45.60000  ? 283 LEU A HD12 1 
ATOM   4362 H  HD13 . LEU A 1 283 ? 26.24700  -20.83500 -52.47000 1.000 45.60000  ? 283 LEU A HD13 1 
ATOM   4363 H  HD21 . LEU A 1 283 ? 25.75700  -18.58600 -50.94400 1.000 46.12000  ? 283 LEU A HD21 1 
ATOM   4364 H  HD22 . LEU A 1 283 ? 26.58100  -19.73500 -50.22000 1.000 46.12000  ? 283 LEU A HD22 1 
ATOM   4365 H  HD23 . LEU A 1 283 ? 27.13200  -18.24500 -50.22400 1.000 46.12000  ? 283 LEU A HD23 1 
ATOM   4366 N  N    . TYR A 1 284 ? 31.21800  -20.06400 -49.31300 1.000 28.34814  ? 284 TYR A N    1 
ATOM   4367 C  CA   . TYR A 1 284 ? 32.30500  -20.90500 -48.83300 1.000 29.43511  ? 284 TYR A CA   1 
ATOM   4368 C  C    . TYR A 1 284 ? 31.71700  -22.16200 -48.21600 1.000 29.75094  ? 284 TYR A C    1 
ATOM   4369 O  O    . TYR A 1 284 ? 30.74400  -22.08700 -47.45800 1.000 29.56670  ? 284 TYR A O    1 
ATOM   4370 C  CB   . TYR A 1 284 ? 33.16700  -20.15800 -47.82200 1.000 29.82200  ? 284 TYR A CB   1 
ATOM   4371 C  CG   . TYR A 1 284 ? 33.94900  -19.01800 -48.39600 1.000 30.09571  ? 284 TYR A CG   1 
ATOM   4372 C  CD1  . TYR A 1 284 ? 34.99700  -19.24700 -49.27400 1.000 32.06437  ? 284 TYR A CD1  1 
ATOM   4373 C  CD2  . TYR A 1 284 ? 33.66000  -17.70900 -48.06000 1.000 35.80956  ? 284 TYR A CD2  1 
ATOM   4374 C  CE1  . TYR A 1 284 ? 35.71700  -18.20600 -49.81300 1.000 35.87009  ? 284 TYR A CE1  1 
ATOM   4375 C  CE2  . TYR A 1 284 ? 34.38000  -16.66500 -48.57700 1.000 35.91746  ? 284 TYR A CE2  1 
ATOM   4376 C  CZ   . TYR A 1 284 ? 35.41000  -16.91400 -49.45300 1.000 33.94091  ? 284 TYR A CZ   1 
ATOM   4377 O  OH   . TYR A 1 284 ? 36.13200  -15.87100 -49.98000 1.000 37.23604  ? 284 TYR A OH   1 
ATOM   4378 H  H    . TYR A 1 284 ? 30.78800  -19.66200 -48.68600 1.000 34.02000  ? 284 TYR A H    1 
ATOM   4379 H  HA   . TYR A 1 284 ? 32.87500  -21.16500 -49.57300 1.000 35.32000  ? 284 TYR A HA   1 
ATOM   4380 H  HB2  . TYR A 1 284 ? 32.59100  -19.79900 -47.12900 1.000 35.79000  ? 284 TYR A HB2  1 
ATOM   4381 H  HB3  . TYR A 1 284 ? 33.80100  -20.78300 -47.43500 1.000 35.79000  ? 284 TYR A HB3  1 
ATOM   4382 H  HD1  . TYR A 1 284 ? 35.21800  -20.12100 -49.50400 1.000 38.48000  ? 284 TYR A HD1  1 
ATOM   4383 H  HD2  . TYR A 1 284 ? 32.96200  -17.53400 -47.47000 1.000 42.97000  ? 284 TYR A HD2  1 
ATOM   4384 H  HE1  . TYR A 1 284 ? 36.40600  -18.37400 -50.41500 1.000 43.05000  ? 284 TYR A HE1  1 
ATOM   4385 H  HE2  . TYR A 1 284 ? 34.17300  -15.79000 -48.33600 1.000 43.10000  ? 284 TYR A HE2  1 
ATOM   4386 H  HH   . TYR A 1 284 ? 35.87300  -15.14500 -49.64700 1.000 44.68000  ? 284 TYR A HH   1 
ATOM   4387 N  N    . CYS A 1 285 ? 32.29000  -23.30300 -48.55100 1.000 30.09571  ? 285 CYS A N    1 
ATOM   4388 C  CA   . CYS A 1 285 ? 31.88400  -24.58700 -47.99300 1.000 29.64829  ? 285 CYS A CA   1 
ATOM   4389 C  C    . CYS A 1 285 ? 33.01100  -25.05800 -47.08300 1.000 29.10349  ? 285 CYS A C    1 
ATOM   4390 O  O    . CYS A 1 285 ? 34.11500  -25.35000 -47.54900 1.000 28.56395  ? 285 CYS A O    1 
ATOM   4391 C  CB   . CYS A 1 285 ? 31.59900  -25.60800 -49.08200 1.000 31.91698  ? 285 CYS A CB   1 
ATOM   4392 S  SG   . CYS A 1 285 ? 31.11100  -27.21800 -48.43600 1.000 34.76469  ? 285 CYS A SG   1 
ATOM   4393 H  H    . CYS A 1 285 ? 32.93500  -23.36400 -49.11600 1.000 36.11000  ? 285 CYS A H    1 
ATOM   4394 H  HA   . CYS A 1 285 ? 31.07200  -24.47600 -47.47500 1.000 35.58000  ? 285 CYS A HA   1 
ATOM   4395 H  HB2  . CYS A 1 285 ? 30.87600  -25.27900 -49.64000 1.000 38.30000  ? 285 CYS A HB2  1 
ATOM   4396 H  HB3  . CYS A 1 285 ? 32.40000  -25.73100 -49.61500 1.000 38.30000  ? 285 CYS A HB3  1 
ATOM   4397 H  HG   . CYS A 1 285 ? 30.89500  -27.95900 -49.35500 1.000 41.72000  ? 285 CYS A HG   1 
ATOM   4398 N  N    . ILE A 1 286 ? 32.73900  -25.10800 -45.78200 1.000 29.35352  ? 286 ILE A N    1 
ATOM   4399 C  CA   . ILE A 1 286 ? 33.73000  -25.48100 -44.78000 1.000 29.64829  ? 286 ILE A CA   1 
ATOM   4400 C  C    . ILE A 1 286 ? 33.39200  -26.88700 -44.31600 1.000 26.53739  ? 286 ILE A C    1 
ATOM   4401 O  O    . ILE A 1 286 ? 32.26900  -27.14300 -43.86700 1.000 29.49564  ? 286 ILE A O    1 
ATOM   4402 C  CB   . ILE A 1 286 ? 33.76000  -24.49000 -43.60500 1.000 31.11162  ? 286 ILE A CB   1 
ATOM   4403 C  CG1  . ILE A 1 286 ? 34.06500  -23.08000 -44.12300 1.000 32.01963  ? 286 ILE A CG1  1 
ATOM   4404 C  CG2  . ILE A 1 286 ? 34.78900  -24.96300 -42.55100 1.000 29.88779  ? 286 ILE A CG2  1 
ATOM   4405 C  CD1  . ILE A 1 286 ? 34.00200  -21.99700 -43.06300 1.000 31.78802  ? 286 ILE A CD1  1 
ATOM   4406 H  H    . ILE A 1 286 ? 31.96800  -24.92600 -45.44800 1.000 35.22000  ? 286 ILE A H    1 
ATOM   4407 H  HA   . ILE A 1 286 ? 34.61400  -25.48900 -45.18000 1.000 35.58000  ? 286 ILE A HA   1 
ATOM   4408 H  HB   . ILE A 1 286 ? 32.89200  -24.45900 -43.17400 1.000 37.33000  ? 286 ILE A HB   1 
ATOM   4409 H  HG12 . ILE A 1 286 ? 34.96000  -23.07300 -44.49700 1.000 38.42000  ? 286 ILE A HG12 1 
ATOM   4410 H  HG13 . ILE A 1 286 ? 33.41700  -22.85600 -44.81000 1.000 38.42000  ? 286 ILE A HG13 1 
ATOM   4411 H  HG21 . ILE A 1 286 ? 34.91900  -24.25800 -41.89800 1.000 35.87000  ? 286 ILE A HG21 1 
ATOM   4412 H  HG22 . ILE A 1 286 ? 34.45000  -25.76000 -42.11500 1.000 35.87000  ? 286 ILE A HG22 1 
ATOM   4413 H  HG23 . ILE A 1 286 ? 35.62800  -25.16100 -42.99600 1.000 35.87000  ? 286 ILE A HG23 1 
ATOM   4414 H  HD11 . ILE A 1 286 ? 34.06900  -21.13000 -43.49300 1.000 38.14000  ? 286 ILE A HD11 1 
ATOM   4415 H  HD12 . ILE A 1 286 ? 33.15800  -22.06700 -42.59000 1.000 38.14000  ? 286 ILE A HD12 1 
ATOM   4416 H  HD13 . ILE A 1 286 ? 34.73900  -22.11800 -42.44500 1.000 38.14000  ? 286 ILE A HD13 1 
ATOM   4417 N  N    . ASP A 1 287 ? 34.33800  -27.80500 -44.46200 1.000 27.94282  ? 287 ASP A N    1 
ATOM   4418 C  CA   . ASP A 1 287 ? 34.16200  -29.21000 -44.07000 1.000 30.54050  ? 287 ASP A CA   1 
ATOM   4419 C  C    . ASP A 1 287 ? 35.29200  -29.50200 -43.08800 1.000 27.67963  ? 287 ASP A C    1 
ATOM   4420 O  O    . ASP A 1 287 ? 36.34300  -30.01300 -43.47900 1.000 28.41920  ? 287 ASP A O    1 
ATOM   4421 C  CB   . ASP A 1 287 ? 34.18200  -30.15400 -45.27600 1.000 28.91662  ? 287 ASP A CB   1 
ATOM   4422 C  CG   . ASP A 1 287 ? 33.93300  -31.61300 -44.90600 1.000 32.60128  ? 287 ASP A CG   1 
ATOM   4423 O  OD1  . ASP A 1 287 ? 33.62500  -31.89400 -43.71900 1.000 33.89880  ? 287 ASP A OD1  1 
ATOM   4424 O  OD2  . ASP A 1 287 ? 34.05900  -32.48200 -45.81200 1.000 35.60953  ? 287 ASP A OD2  1 
ATOM   4425 H  H    . ASP A 1 287 ? 35.11400  -27.64000 -44.79500 1.000 33.53000  ? 287 ASP A H    1 
ATOM   4426 H  HA   . ASP A 1 287 ? 33.30300  -29.33400 -43.63700 1.000 36.65000  ? 287 ASP A HA   1 
ATOM   4427 H  HB2  . ASP A 1 287 ? 33.49000  -29.88300 -45.89900 1.000 34.70000  ? 287 ASP A HB2  1 
ATOM   4428 H  HB3  . ASP A 1 287 ? 35.05200  -30.10000 -45.70300 1.000 34.70000  ? 287 ASP A HB3  1 
ATOM   4429 N  N    . GLY A 1 288 ? 35.07500  -29.17700 -41.82200 1.000 30.46155  ? 288 GLY A N    1 
ATOM   4430 C  CA   . GLY A 1 288 ? 36.13900  -29.29700 -40.84400 1.000 32.32230  ? 288 GLY A CA   1 
ATOM   4431 C  C    . GLY A 1 288 ? 37.30400  -28.39500 -41.19000 1.000 30.16414  ? 288 GLY A C    1 
ATOM   4432 O  O    . GLY A 1 288 ? 37.16600  -27.17100 -41.15800 1.000 30.44839  ? 288 GLY A O    1 
ATOM   4433 H  H    . GLY A 1 288 ? 34.32800  -28.88700 -41.51000 1.000 36.56000  ? 288 GLY A H    1 
ATOM   4434 H  HA2  . GLY A 1 288 ? 35.80400  -29.05100 -39.96800 1.000 38.79000  ? 288 GLY A HA2  1 
ATOM   4435 H  HA3  . GLY A 1 288 ? 36.45300  -30.21400 -40.81600 1.000 38.79000  ? 288 GLY A HA3  1 
ATOM   4436 N  N    . ALA A 1 289 ? 38.45400  -28.98600 -41.52100 1.000 29.56670  ? 289 ALA A N    1 
ATOM   4437 C  CA   . ALA A 1 289 ? 39.62700  -28.21800 -41.91400 1.000 29.65356  ? 289 ALA A CA   1 
ATOM   4438 C  C    . ALA A 1 289 ? 39.59900  -27.81200 -43.38100 1.000 28.55079  ? 289 ALA A C    1 
ATOM   4439 O  O    . ALA A 1 289 ? 40.44000  -27.01200 -43.80600 1.000 31.22480  ? 289 ALA A O    1 
ATOM   4440 C  CB   . ALA A 1 289 ? 40.90000  -29.02600 -41.65900 1.000 30.25363  ? 289 ALA A CB   1 
ATOM   4441 H  H    . ALA A 1 289 ? 38.57700  -29.83700 -41.52500 1.000 35.48000  ? 289 ALA A H    1 
ATOM   4442 H  HA   . ALA A 1 289 ? 39.66100  -27.41600 -41.36900 1.000 35.58000  ? 289 ALA A HA   1 
ATOM   4443 H  HB1  . ALA A 1 289 ? 41.66800  -28.49500 -41.92100 1.000 36.31000  ? 289 ALA A HB1  1 
ATOM   4444 H  HB2  . ALA A 1 289 ? 40.95300  -29.24200 -40.71500 1.000 36.31000  ? 289 ALA A HB2  1 
ATOM   4445 H  HB3  . ALA A 1 289 ? 40.86700  -29.84100 -42.18400 1.000 36.31000  ? 289 ALA A HB3  1 
ATOM   4446 N  N    . LEU A 1 290 ? 38.68100  -28.36300 -44.15900 1.000 31.17216  ? 290 LEU A N    1 
ATOM   4447 C  CA   . LEU A 1 290 ? 38.69800  -28.20100 -45.60100 1.000 29.22456  ? 290 LEU A CA   1 
ATOM   4448 C  C    . LEU A 1 290 ? 37.83100  -27.03100 -46.03400 1.000 28.89820  ? 290 LEU A C    1 
ATOM   4449 O  O    . LEU A 1 290 ? 36.78500  -26.75500 -45.44700 1.000 31.13794  ? 290 LEU A O    1 
ATOM   4450 C  CB   . LEU A 1 290 ? 38.19700  -29.47400 -46.28100 1.000 32.07227  ? 290 LEU A CB   1 
ATOM   4451 C  CG   . LEU A 1 290 ? 38.76200  -30.80100 -45.78200 1.000 37.60188  ? 290 LEU A CG   1 
ATOM   4452 C  CD1  . LEU A 1 290 ? 38.09900  -31.95000 -46.50500 1.000 45.38176  ? 290 LEU A CD1  1 
ATOM   4453 C  CD2  . LEU A 1 290 ? 40.25000  -30.82300 -46.04100 1.000 40.07849  ? 290 LEU A CD2  1 
ATOM   4454 H  H    . LEU A 1 290 ? 38.02800  -28.84400 -43.87100 1.000 37.41000  ? 290 LEU A H    1 
ATOM   4455 H  HA   . LEU A 1 290 ? 39.60800  -28.02200 -45.88500 1.000 35.07000  ? 290 LEU A HA   1 
ATOM   4456 H  HB2  . LEU A 1 290 ? 37.23500  -29.51600 -46.16400 1.000 38.48000  ? 290 LEU A HB2  1 
ATOM   4457 H  HB3  . LEU A 1 290 ? 38.41400  -29.41300 -47.22400 1.000 38.48000  ? 290 LEU A HB3  1 
ATOM   4458 H  HG   . LEU A 1 290 ? 38.59500  -30.90200 -44.83100 1.000 45.12000  ? 290 LEU A HG   1 
ATOM   4459 H  HD11 . LEU A 1 290 ? 38.46000  -32.78500 -46.16900 1.000 54.46000  ? 290 LEU A HD11 1 
ATOM   4460 H  HD12 . LEU A 1 290 ? 37.14300  -31.91500 -46.34500 1.000 54.46000  ? 290 LEU A HD12 1 
ATOM   4461 H  HD13 . LEU A 1 290 ? 38.27800  -31.87000 -47.45500 1.000 54.46000  ? 290 LEU A HD13 1 
ATOM   4462 H  HD21 . LEU A 1 290 ? 40.60300  -31.68800 -45.78100 1.000 48.09000  ? 290 LEU A HD21 1 
ATOM   4463 H  HD22 . LEU A 1 290 ? 40.40800  -30.67200 -46.98600 1.000 48.09000  ? 290 LEU A HD22 1 
ATOM   4464 H  HD23 . LEU A 1 290 ? 40.67200  -30.12300 -45.51900 1.000 48.09000  ? 290 LEU A HD23 1 
ATOM   4465 N  N    . LEU A 1 291 ? 38.24700  -26.37500 -47.12200 1.000 30.17204  ? 291 LEU A N    1 
ATOM   4466 C  CA   . LEU A 1 291 ? 37.53400  -25.19500 -47.58500 1.000 28.59027  ? 291 LEU A CA   1 
ATOM   4467 C  C    . LEU A 1 291 ? 37.50500  -25.22000 -49.10300 1.000 26.93744  ? 291 LEU A C    1 
ATOM   4468 O  O    . LEU A 1 291 ? 38.54000  -25.43100 -49.73800 1.000 30.54050  ? 291 LEU A O    1 
ATOM   4469 C  CB   . LEU A 1 291 ? 38.21400  -23.91100 -47.11700 1.000 31.59589  ? 291 LEU A CB   1 
ATOM   4470 C  CG   . LEU A 1 291 ? 37.62000  -22.59100 -47.60900 1.000 34.06461  ? 291 LEU A CG   1 
ATOM   4471 C  CD1  . LEU A 1 291 ? 36.23600  -22.34100 -47.07900 1.000 31.80381  ? 291 LEU A CD1  1 
ATOM   4472 C  CD2  . LEU A 1 291 ? 38.56000  -21.44300 -47.22500 1.000 35.24107  ? 291 LEU A CD2  1 
ATOM   4473 H  H    . LEU A 1 291 ? 38.93000  -26.59400 -47.59700 1.000 36.21000  ? 291 LEU A H    1 
ATOM   4474 H  HA   . LEU A 1 291 ? 36.62700  -25.20800 -47.24100 1.000 34.31000  ? 291 LEU A HA   1 
ATOM   4475 H  HB2  . LEU A 1 291 ? 38.18200  -23.89200 -46.14800 1.000 37.91000  ? 291 LEU A HB2  1 
ATOM   4476 H  HB3  . LEU A 1 291 ? 39.13600  -23.93500 -47.41700 1.000 37.91000  ? 291 LEU A HB3  1 
ATOM   4477 H  HG   . LEU A 1 291 ? 37.53100  -22.63700 -48.57400 1.000 40.88000  ? 291 LEU A HG   1 
ATOM   4478 H  HD11 . LEU A 1 291 ? 35.89100  -21.52400 -47.47100 1.000 38.16000  ? 291 LEU A HD11 1 
ATOM   4479 H  HD12 . LEU A 1 291 ? 35.66600  -23.08900 -47.31700 1.000 38.16000  ? 291 LEU A HD12 1 
ATOM   4480 H  HD13 . LEU A 1 291 ? 36.27800  -22.25200 -46.11400 1.000 38.16000  ? 291 LEU A HD13 1 
ATOM   4481 H  HD21 . LEU A 1 291 ? 38.15700  -20.60300 -47.49300 1.000 42.29000  ? 291 LEU A HD21 1 
ATOM   4482 H  HD22 . LEU A 1 291 ? 38.69600  -21.45400 -46.26500 1.000 42.29000  ? 291 LEU A HD22 1 
ATOM   4483 H  HD23 . LEU A 1 291 ? 39.40800  -21.56400 -47.68100 1.000 42.29000  ? 291 LEU A HD23 1 
ATOM   4484 N  N    . THR A 1 292 ? 36.32500  -24.99900 -49.67200 1.000 28.75871  ? 292 THR A N    1 
ATOM   4485 C  CA   . THR A 1 292 ? 36.15400  -24.76400 -51.10000 1.000 29.08507  ? 292 THR A CA   1 
ATOM   4486 C  C    . THR A 1 292 ? 35.21300  -23.57700 -51.27300 1.000 31.32744  ? 292 THR A C    1 
ATOM   4487 O  O    . THR A 1 292 ? 34.53000  -23.16100 -50.34000 1.000 31.14058  ? 292 THR A O    1 
ATOM   4488 C  CB   . THR A 1 292 ? 35.60300  -26.00000 -51.83200 1.000 30.90371  ? 292 THR A CB   1 
ATOM   4489 O  OG1  . THR A 1 292 ? 34.31900  -26.35500 -51.26800 1.000 30.16941  ? 292 THR A OG1  1 
ATOM   4490 C  CG2  . THR A 1 292 ? 36.56300  -27.16200 -51.71900 1.000 33.94881  ? 292 THR A CG2  1 
ATOM   4491 H  H    . THR A 1 292 ? 35.58300  -24.98100 -49.23600 1.000 34.51000  ? 292 THR A H    1 
ATOM   4492 H  HA   . THR A 1 292 ? 37.01200  -24.55500 -51.50100 1.000 34.90000  ? 292 THR A HA   1 
ATOM   4493 H  HB   . THR A 1 292 ? 35.49300  -25.80200 -52.77500 1.000 37.08000  ? 292 THR A HB   1 
ATOM   4494 H  HG1  . THR A 1 292 ? 34.01600  -27.03800 -51.65100 1.000 36.20000  ? 292 THR A HG1  1 
ATOM   4495 H  HG21 . THR A 1 292 ? 36.24200  -27.91000 -52.24600 1.000 40.74000  ? 292 THR A HG21 1 
ATOM   4496 H  HG22 . THR A 1 292 ? 37.43900  -26.90100 -52.04400 1.000 40.74000  ? 292 THR A HG22 1 
ATOM   4497 H  HG23 . THR A 1 292 ? 36.64100  -27.44000 -50.79300 1.000 40.74000  ? 292 THR A HG23 1 
ATOM   4498 N  N    . LYS A 1 293 ? 35.17300  -23.02800 -52.49200 1.000 31.32481  ? 293 LYS A N    1 
ATOM   4499 C  CA   . LYS A 1 293 ? 34.31200  -21.88700 -52.76900 1.000 32.23018  ? 293 LYS A CA   1 
ATOM   4500 C  C    . LYS A 1 293 ? 33.56400  -22.12000 -54.07300 1.000 32.16175  ? 293 LYS A C    1 
ATOM   4501 O  O    . LYS A 1 293 ? 34.00500  -22.88900 -54.93900 1.000 34.43044  ? 293 LYS A O    1 
ATOM   4502 C  CB   . LYS A 1 293 ? 35.11400  -20.57400 -52.86800 1.000 35.84640  ? 293 LYS A CB   1 
ATOM   4503 C  CG   . LYS A 1 293 ? 35.89600  -20.42300 -54.14500 1.000 38.74675  ? 293 LYS A CG   1 
ATOM   4504 C  CD   . LYS A 1 293 ? 36.57600  -19.05700 -54.23700 1.000 39.57317  ? 293 LYS A CD   1 
ATOM   4505 C  CE   . LYS A 1 293 ? 37.10800  -18.81300 -55.64100 1.000 44.65009  ? 293 LYS A CE   1 
ATOM   4506 N  NZ   . LYS A 1 293 ? 37.54400  -17.40500 -55.78200 1.000 59.10709  ? 293 LYS A NZ   1 
ATOM   4507 H  H    . LYS A 1 293 ? 35.63300  -23.30100 -53.16500 1.000 37.59000  ? 293 LYS A H    1 
ATOM   4508 H  HA   . LYS A 1 293 ? 33.66600  -21.79900 -52.05000 1.000 38.68000  ? 293 LYS A HA   1 
ATOM   4509 H  HB2  . LYS A 1 293 ? 34.49600  -19.82800 -52.81200 1.000 43.02000  ? 293 LYS A HB2  1 
ATOM   4510 H  HB3  . LYS A 1 293 ? 35.74400  -20.53900 -52.13200 1.000 43.02000  ? 293 LYS A HB3  1 
ATOM   4511 H  HG2  . LYS A 1 293 ? 36.58400  -21.10700 -54.18200 1.000 46.49000  ? 293 LYS A HG2  1 
ATOM   4512 H  HG3  . LYS A 1 293 ? 35.29600  -20.51500 -54.90100 1.000 46.49000  ? 293 LYS A HG3  1 
ATOM   4513 H  HD2  . LYS A 1 293 ? 35.93400  -18.36100 -54.02600 1.000 47.49000  ? 293 LYS A HD2  1 
ATOM   4514 H  HD3  . LYS A 1 293 ? 37.31900  -19.02200 -53.61600 1.000 47.49000  ? 293 LYS A HD3  1 
ATOM   4515 H  HE2  . LYS A 1 293 ? 37.86900  -19.39100 -55.80600 1.000 53.58000  ? 293 LYS A HE2  1 
ATOM   4516 H  HE3  . LYS A 1 293 ? 36.41000  -18.98900 -56.29000 1.000 53.58000  ? 293 LYS A HE3  1 
ATOM   4517 H  HZ1  . LYS A 1 293 ? 38.19600  -17.22800 -55.20300 1.000 70.93000  ? 293 LYS A HZ1  1 
ATOM   4518 H  HZ2  . LYS A 1 293 ? 37.84400  -17.26100 -56.60800 1.000 70.93000  ? 293 LYS A HZ2  1 
ATOM   4519 H  HZ3  . LYS A 1 293 ? 36.86100  -16.85700 -55.62400 1.000 70.93000  ? 293 LYS A HZ3  1 
ATOM   4520 N  N    . SER A 1 294 ? 32.44300  -21.40800 -54.22700 1.000 33.78563  ? 294 SER A N    1 
ATOM   4521 C  CA   . SER A 1 294 ? 31.65300  -21.47900 -55.45600 1.000 34.32517  ? 294 SER A CA   1 
ATOM   4522 C  C    . SER A 1 294 ? 30.69900  -20.29400 -55.51100 1.000 35.03315  ? 294 SER A C    1 
ATOM   4523 O  O    . SER A 1 294 ? 30.36500  -19.69900 -54.49000 1.000 36.65703  ? 294 SER A O    1 
ATOM   4524 C  CB   . SER A 1 294 ? 30.88300  -22.80400 -55.55400 1.000 35.53847  ? 294 SER A CB   1 
ATOM   4525 O  OG   . SER A 1 294 ? 29.89500  -22.89700 -54.54600 1.000 37.31500  ? 294 SER A OG   1 
ATOM   4526 H  H    . SER A 1 294 ? 32.12000  -20.87800 -53.63200 1.000 40.54000  ? 294 SER A H    1 
ATOM   4527 H  HA   . SER A 1 294 ? 32.24900  -21.41300 -56.21800 1.000 41.19000  ? 294 SER A HA   1 
ATOM   4528 H  HB2  . SER A 1 294 ? 30.45200  -22.85400 -56.42200 1.000 42.65000  ? 294 SER A HB2  1 
ATOM   4529 H  HB3  . SER A 1 294 ? 31.50800  -23.53900 -55.45200 1.000 42.65000  ? 294 SER A HB3  1 
ATOM   4530 H  HG   . SER A 1 294 ? 29.49000  -23.63100 -54.60700 1.000 44.78000  ? 294 SER A HG   1 
ATOM   4531 N  N    . SER A 1 295 ? 30.27300  -19.94500 -56.72600 1.000 33.79879  ? 295 SER A N    1 
ATOM   4532 C  CA   . SER A 1 295 ? 29.32800  -18.83500 -56.85500 1.000 35.45951  ? 295 SER A CA   1 
ATOM   4533 C  C    . SER A 1 295 ? 27.89300  -19.28500 -56.59700 1.000 39.23892  ? 295 SER A C    1 
ATOM   4534 O  O    . SER A 1 295 ? 27.07600  -18.49000 -56.11600 1.000 41.22863  ? 295 SER A O    1 
ATOM   4535 C  CB   . SER A 1 295 ? 29.45900  -18.20600 -58.23700 1.000 39.45210  ? 295 SER A CB   1 
ATOM   4536 O  OG   . SER A 1 295 ? 29.35300  -19.19600 -59.22800 1.000 47.96628  ? 295 SER A OG   1 
ATOM   4537 H  H    . SER A 1 295 ? 30.50700  -20.32100 -57.46400 1.000 40.56000  ? 295 SER A H    1 
ATOM   4538 H  HA   . SER A 1 295 ? 29.54100  -18.15100 -56.20100 1.000 42.55000  ? 295 SER A HA   1 
ATOM   4539 H  HB2  . SER A 1 295 ? 28.75000  -17.55500 -58.35900 1.000 47.34000  ? 295 SER A HB2  1 
ATOM   4540 H  HB3  . SER A 1 295 ? 30.32400  -17.77300 -58.30900 1.000 47.34000  ? 295 SER A HB3  1 
ATOM   4541 H  HG   . SER A 1 295 ? 29.42100  -18.84900 -59.99000 1.000 57.56000  ? 295 SER A HG   1 
ATOM   4542 N  N    . GLU A 1 296 ? 27.58500  -20.55100 -56.87400 1.000 39.06784  ? 296 GLU A N    1 
ATOM   4543 C  CA   . GLU A 1 296 ? 26.27200  -21.13900 -56.64700 1.000 41.25231  ? 296 GLU A CA   1 
ATOM   4544 C  C    . GLU A 1 296 ? 26.45700  -22.39800 -55.81100 1.000 39.09942  ? 296 GLU A C    1 
ATOM   4545 O  O    . GLU A 1 296 ? 27.56200  -22.93100 -55.70400 1.000 38.74149  ? 296 GLU A O    1 
ATOM   4546 C  CB   . GLU A 1 296 ? 25.59100  -21.45000 -57.98200 1.000 45.56862  ? 296 GLU A CB   1 
ATOM   4547 C  CG   . GLU A 1 296 ? 25.17800  -20.19000 -58.75000 1.000 53.50905  ? 296 GLU A CG   1 
ATOM   4548 C  CD   . GLU A 1 296 ? 24.51500  -20.50800 -60.07800 1.000 80.37279  ? 296 GLU A CD   1 
ATOM   4549 O  OE1  . GLU A 1 296 ? 24.35200  -21.70700 -60.39200 1.000 83.32315  ? 296 GLU A OE1  1 
ATOM   4550 O  OE2  . GLU A 1 296 ? 24.16300  -19.55800 -60.81100 1.000 83.00469  ? 296 GLU A OE2  1 
ATOM   4551 H  H    . GLU A 1 296 ? 28.14600  -21.11100 -57.20800 1.000 46.88000  ? 296 GLU A H    1 
ATOM   4552 H  HA   . GLU A 1 296 ? 25.69100  -20.53800 -56.15500 1.000 49.50000  ? 296 GLU A HA   1 
ATOM   4553 H  HB2  . GLU A 1 296 ? 26.20600  -21.95200 -58.54000 1.000 54.68000  ? 296 GLU A HB2  1 
ATOM   4554 H  HB3  . GLU A 1 296 ? 24.79200  -21.97300 -57.81400 1.000 54.68000  ? 296 GLU A HB3  1 
ATOM   4555 H  HG2  . GLU A 1 296 ? 24.54800  -19.68400 -58.21300 1.000 64.21000  ? 296 GLU A HG2  1 
ATOM   4556 H  HG3  . GLU A 1 296 ? 25.96700  -19.65500 -58.92900 1.000 64.21000  ? 296 GLU A HG3  1 
ATOM   4557 N  N    . TYR A 1 297 ? 25.38000  -22.86400 -55.18400 1.000 37.09129  ? 297 TYR A N    1 
ATOM   4558 C  CA   . TYR A 1 297 ? 25.49000  -24.04900 -54.33900 1.000 35.18317  ? 297 TYR A CA   1 
ATOM   4559 C  C    . TYR A 1 297 ? 24.16100  -24.77700 -54.31900 1.000 38.38881  ? 297 TYR A C    1 
ATOM   4560 O  O    . TYR A 1 297 ? 23.12200  -24.15800 -54.06500 1.000 42.97357  ? 297 TYR A O    1 
ATOM   4561 C  CB   . TYR A 1 297 ? 25.90600  -23.71500 -52.90200 1.000 35.98326  ? 297 TYR A CB   1 
ATOM   4562 C  CG   . TYR A 1 297 ? 26.45000  -24.92800 -52.16900 1.000 36.10959  ? 297 TYR A CG   1 
ATOM   4563 C  CD1  . TYR A 1 297 ? 25.60200  -25.86000 -51.57200 1.000 36.27803  ? 297 TYR A CD1  1 
ATOM   4564 C  CD2  . TYR A 1 297 ? 27.82200  -25.16300 -52.11400 1.000 42.51562  ? 297 TYR A CD2  1 
ATOM   4565 C  CE1  . TYR A 1 297 ? 26.11900  -26.99000 -50.91100 1.000 34.68311  ? 297 TYR A CE1  1 
ATOM   4566 C  CE2  . TYR A 1 297 ? 28.34100  -26.28200 -51.47400 1.000 42.01820  ? 297 TYR A CE2  1 
ATOM   4567 C  CZ   . TYR A 1 297 ? 27.49100  -27.18900 -50.87600 1.000 39.55737  ? 297 TYR A CZ   1 
ATOM   4568 O  OH   . TYR A 1 297 ? 28.03600  -28.29700 -50.24200 1.000 42.22348  ? 297 TYR A OH   1 
ATOM   4569 H  H    . TYR A 1 297 ? 24.59300  -22.51900 -55.23100 1.000 44.51000  ? 297 TYR A H    1 
ATOM   4570 H  HA   . TYR A 1 297 ? 26.16700  -24.62600 -54.72400 1.000 42.22000  ? 297 TYR A HA   1 
ATOM   4571 H  HB2  . TYR A 1 297 ? 26.59800  -23.03600 -52.92000 1.000 43.18000  ? 297 TYR A HB2  1 
ATOM   4572 H  HB3  . TYR A 1 297 ? 25.13300  -23.38800 -52.41500 1.000 43.18000  ? 297 TYR A HB3  1 
ATOM   4573 H  HD1  . TYR A 1 297 ? 24.68100  -25.73300 -51.61100 1.000 43.53000  ? 297 TYR A HD1  1 
ATOM   4574 H  HD2  . TYR A 1 297 ? 28.40300  -24.55800 -52.51400 1.000 51.02000  ? 297 TYR A HD2  1 
ATOM   4575 H  HE1  . TYR A 1 297 ? 25.54600  -27.59700 -50.50100 1.000 41.62000  ? 297 TYR A HE1  1 
ATOM   4576 H  HE2  . TYR A 1 297 ? 29.26100  -26.41900 -51.45000 1.000 50.42000  ? 297 TYR A HE2  1 
ATOM   4577 H  HH   . TYR A 1 297 ? 27.46000  -28.90600 -50.18200 1.000 50.67000  ? 297 TYR A HH   1 
ATOM   4578 N  N    . LYS A 1 298 ? 24.20400  -26.07900 -54.59200 1.000 40.10744  ? 298 LYS A N    1 
ATOM   4579 C  CA   . LYS A 1 298 ? 23.05500  -26.96700 -54.48300 1.000 38.24143  ? 298 LYS A CA   1 
ATOM   4580 C  C    . LYS A 1 298 ? 23.52000  -28.20900 -53.74600 1.000 38.66779  ? 298 LYS A C    1 
ATOM   4581 O  O    . LYS A 1 298 ? 24.59800  -28.74500 -54.02300 1.000 40.05217  ? 298 LYS A O    1 
ATOM   4582 C  CB   . LYS A 1 298 ? 22.45900  -27.37700 -55.84200 1.000 40.50486  ? 298 LYS A CB   1 
ATOM   4583 C  CG   . LYS A 1 298 ? 21.84700  -26.25100 -56.67100 1.000 61.62318  ? 298 LYS A CG   1 
ATOM   4584 C  CD   . LYS A 1 298 ? 20.75000  -26.76700 -57.63000 1.000 76.53023  ? 298 LYS A CD   1 
ATOM   4585 C  CE   . LYS A 1 298 ? 20.16200  -25.63300 -58.48800 1.000 82.92310  ? 298 LYS A CE   1 
ATOM   4586 N  NZ   . LYS A 1 298 ? 18.70400  -25.37200 -58.26500 1.000 90.54243  ? 298 LYS A NZ   1 
ATOM   4587 H  H    . LYS A 1 298 ? 24.91700  -26.48400 -54.85200 1.000 48.13000  ? 298 LYS A H    1 
ATOM   4588 H  HA   . LYS A 1 298 ? 22.34500  -26.51600 -54.00000 1.000 45.89000  ? 298 LYS A HA   1 
ATOM   4589 H  HB2  . LYS A 1 298 ? 23.16500  -27.77400 -56.37600 1.000 48.61000  ? 298 LYS A HB2  1 
ATOM   4590 H  HB3  . LYS A 1 298 ? 21.75800  -28.02800 -55.68200 1.000 48.61000  ? 298 LYS A HB3  1 
ATOM   4591 H  HG2  . LYS A 1 298 ? 21.44600  -25.59800 -56.07600 1.000 73.95000  ? 298 LYS A HG2  1 
ATOM   4592 H  HG3  . LYS A 1 298 ? 22.54100  -25.83200 -57.20300 1.000 73.95000  ? 298 LYS A HG3  1 
ATOM   4593 H  HD2  . LYS A 1 298 ? 21.13100  -27.43200 -58.22500 1.000 91.84000  ? 298 LYS A HD2  1 
ATOM   4594 H  HD3  . LYS A 1 298 ? 20.03000  -27.16000 -57.11200 1.000 91.84000  ? 298 LYS A HD3  1 
ATOM   4595 H  HE2  . LYS A 1 298 ? 20.64000  -24.81400 -58.28500 1.000 99.51000  ? 298 LYS A HE2  1 
ATOM   4596 H  HE3  . LYS A 1 298 ? 20.27800  -25.86200 -59.42300 1.000 99.51000  ? 298 LYS A HE3  1 
ATOM   4597 H  HZ1  . LYS A 1 298 ? 18.42900  -24.71000 -58.79300 1.000 108.65000 ? 298 LYS A HZ1  1 
ATOM   4598 H  HZ2  . LYS A 1 298 ? 18.23100  -26.10300 -58.45000 1.000 108.65000 ? 298 LYS A HZ2  1 
ATOM   4599 H  HZ3  . LYS A 1 298 ? 18.56100  -25.14300 -57.41700 1.000 108.65000 ? 298 LYS A HZ3  1 
ATOM   4600 N  N    . GLY A 1 299 ? 22.72500  -28.66100 -52.79600 1.000 38.80992  ? 299 GLY A N    1 
ATOM   4601 C  CA   . GLY A 1 299 ? 23.06300  -29.85200 -52.06500 1.000 37.74137  ? 299 GLY A CA   1 
ATOM   4602 C  C    . GLY A 1 299 ? 21.96100  -30.21900 -51.10700 1.000 33.17503  ? 299 GLY A C    1 
ATOM   4603 O  O    . GLY A 1 299 ? 20.95100  -29.51800 -50.98900 1.000 33.67246  ? 299 GLY A O    1 
ATOM   4604 H  H    . GLY A 1 299 ? 21.98500  -28.29200 -52.55900 1.000 46.57000  ? 299 GLY A H    1 
ATOM   4605 H  HA2  . GLY A 1 299 ? 23.19900  -30.58800 -52.68200 1.000 45.29000  ? 299 GLY A HA2  1 
ATOM   4606 H  HA3  . GLY A 1 299 ? 23.88000  -29.70700 -51.56200 1.000 45.29000  ? 299 GLY A HA3  1 
ATOM   4607 N  N    . PRO A 1 300 ? 22.13700  -31.32100 -50.40600 1.000 35.90430  ? 300 PRO A N    1 
ATOM   4608 C  CA   . PRO A 1 300 ? 21.13200  -31.78000 -49.42000 1.000 31.54852  ? 300 PRO A CA   1 
ATOM   4609 C  C    . PRO A 1 300 ? 21.21700  -30.96800 -48.12900 1.000 31.52220  ? 300 PRO A C    1 
ATOM   4610 O  O    . PRO A 1 300 ? 21.88200  -31.32900 -47.15400 1.000 35.49899  ? 300 PRO A O    1 
ATOM   4611 C  CB   . PRO A 1 300 ? 21.50800  -33.24900 -49.22300 1.000 32.76445  ? 300 PRO A CB   1 
ATOM   4612 C  CG   . PRO A 1 300 ? 22.98700  -33.28400 -49.48700 1.000 35.90694  ? 300 PRO A CG   1 
ATOM   4613 C  CD   . PRO A 1 300 ? 23.28500  -32.24300 -50.50900 1.000 34.60415  ? 300 PRO A CD   1 
ATOM   4614 H  HA   . PRO A 1 300 ? 20.23200  -31.74100 -49.77900 1.000 37.86000  ? 300 PRO A HA   1 
ATOM   4615 H  HB2  . PRO A 1 300 ? 21.30700  -33.52700 -48.31500 1.000 39.32000  ? 300 PRO A HB2  1 
ATOM   4616 H  HB3  . PRO A 1 300 ? 21.02600  -33.80600 -49.85400 1.000 39.32000  ? 300 PRO A HB3  1 
ATOM   4617 H  HG2  . PRO A 1 300 ? 23.46400  -33.09500 -48.66400 1.000 43.09000  ? 300 PRO A HG2  1 
ATOM   4618 H  HG3  . PRO A 1 300 ? 23.23300  -34.16200 -49.81800 1.000 43.09000  ? 300 PRO A HG3  1 
ATOM   4619 H  HD2  . PRO A 1 300 ? 24.11400  -31.78500 -50.30200 1.000 41.53000  ? 300 PRO A HD2  1 
ATOM   4620 H  HD3  . PRO A 1 300 ? 23.33400  -32.63400 -51.39500 1.000 41.53000  ? 300 PRO A HD3  1 
ATOM   4621 N  N    . ILE A 1 301 ? 20.53700  -29.83000 -48.13000 1.000 32.73024  ? 301 ILE A N    1 
ATOM   4622 C  CA   . ILE A 1 301 ? 20.56200  -28.91700 -46.99700 1.000 29.07717  ? 301 ILE A CA   1 
ATOM   4623 C  C    . ILE A 1 301 ? 19.52800  -29.35500 -45.97900 1.000 30.90371  ? 301 ILE A C    1 
ATOM   4624 O  O    . ILE A 1 301 ? 18.42500  -29.80100 -46.32400 1.000 29.26930  ? 301 ILE A O    1 
ATOM   4625 C  CB   . ILE A 1 301 ? 20.29500  -27.47600 -47.45200 1.000 29.10086  ? 301 ILE A CB   1 
ATOM   4626 C  CG1  . ILE A 1 301 ? 21.27300  -27.05900 -48.56200 1.000 29.87200  ? 301 ILE A CG1  1 
ATOM   4627 C  CG2  . ILE A 1 301 ? 20.41700  -26.50000 -46.28900 1.000 30.97477  ? 301 ILE A CG2  1 
ATOM   4628 C  CD1  . ILE A 1 301 ? 22.71900  -27.44000 -48.26500 1.000 33.91459  ? 301 ILE A CD1  1 
ATOM   4629 H  H    . ILE A 1 301 ? 20.04600  -29.56100 -48.78300 1.000 39.27000  ? 301 ILE A H    1 
ATOM   4630 H  HA   . ILE A 1 301 ? 21.44100  -28.95400 -46.58900 1.000 34.89000  ? 301 ILE A HA   1 
ATOM   4631 H  HB   . ILE A 1 301 ? 19.38900  -27.45100 -47.79600 1.000 34.92000  ? 301 ILE A HB   1 
ATOM   4632 H  HG12 . ILE A 1 301 ? 21.01300  -27.49600 -49.38900 1.000 35.85000  ? 301 ILE A HG12 1 
ATOM   4633 H  HG13 . ILE A 1 301 ? 21.23400  -26.09600 -48.67000 1.000 35.85000  ? 301 ILE A HG13 1 
ATOM   4634 H  HG21 . ILE A 1 301 ? 20.38900  -25.59300 -46.63400 1.000 37.17000  ? 301 ILE A HG21 1 
ATOM   4635 H  HG22 . ILE A 1 301 ? 19.67800  -26.64400 -45.67700 1.000 37.17000  ? 301 ILE A HG22 1 
ATOM   4636 H  HG23 . ILE A 1 301 ? 21.25900  -26.65500 -45.83400 1.000 37.17000  ? 301 ILE A HG23 1 
ATOM   4637 H  HD11 . ILE A 1 301 ? 23.30000  -26.99900 -48.90500 1.000 40.70000  ? 301 ILE A HD11 1 
ATOM   4638 H  HD12 . ILE A 1 301 ? 22.94200  -27.15400 -47.36500 1.000 40.70000  ? 301 ILE A HD12 1 
ATOM   4639 H  HD13 . ILE A 1 301 ? 22.81500  -28.40200 -48.34000 1.000 40.70000  ? 301 ILE A HD13 1 
ATOM   4640 N  N    . THR A 1 302 ? 19.86700  -29.19800 -44.71100 1.000 30.66420  ? 302 THR A N    1 
ATOM   4641 C  CA   . THR A 1 302 ? 18.95300  -29.54600 -43.63600 1.000 31.14847  ? 302 THR A CA   1 
ATOM   4642 C  C    . THR A 1 302 ? 18.69400  -28.41400 -42.65200 1.000 29.56144  ? 302 THR A C    1 
ATOM   4643 O  O    . THR A 1 302 ? 17.63200  -28.42600 -42.02100 1.000 27.93756  ? 302 THR A O    1 
ATOM   4644 C  CB   . THR A 1 302 ? 19.47300  -30.80200 -42.90900 1.000 34.32780  ? 302 THR A CB   1 
ATOM   4645 O  OG1  . THR A 1 302 ? 18.42100  -31.34200 -42.10100 1.000 37.32290  ? 302 THR A OG1  1 
ATOM   4646 C  CG2  . THR A 1 302 ? 20.73100  -30.46300 -42.14900 1.000 27.02166  ? 302 THR A CG2  1 
ATOM   4647 H  H    . THR A 1 302 ? 20.62500  -28.89100 -44.44600 1.000 36.80000  ? 302 THR A H    1 
ATOM   4648 H  HA   . THR A 1 302 ? 18.08400  -29.77400 -44.00100 1.000 37.38000  ? 302 THR A HA   1 
ATOM   4649 H  HB   . THR A 1 302 ? 19.72800  -31.50700 -43.52500 1.000 41.19000  ? 302 THR A HB   1 
ATOM   4650 H  HG1  . THR A 1 302 ? 18.68200  -32.04300 -41.72000 1.000 44.79000  ? 302 THR A HG1  1 
ATOM   4651 H  HG21 . THR A 1 302 ? 21.26000  -31.26300 -42.00800 1.000 32.43000  ? 302 THR A HG21 1 
ATOM   4652 H  HG22 . THR A 1 302 ? 21.25800  -29.82100 -42.65000 1.000 32.43000  ? 302 THR A HG22 1 
ATOM   4653 H  HG23 . THR A 1 302 ? 20.50400  -30.07900 -41.28800 1.000 32.43000  ? 302 THR A HG23 1 
ATOM   4654 N  N    . ASP A 1 303 ? 19.57400  -27.41700 -42.54800 1.000 27.76386  ? 303 ASP A N    1 
ATOM   4655 C  CA   . ASP A 1 303 ? 19.35200  -26.24600 -41.69500 1.000 26.87164  ? 303 ASP A CA   1 
ATOM   4656 C  C    . ASP A 1 303 ? 19.87300  -24.98100 -42.35900 1.000 28.81924  ? 303 ASP A C    1 
ATOM   4657 O  O    . ASP A 1 303 ? 20.97500  -24.97500 -42.92100 1.000 30.62999  ? 303 ASP A O    1 
ATOM   4658 C  CB   . ASP A 1 303 ? 20.04700  -26.38500 -40.31100 1.000 28.44288  ? 303 ASP A CB   1 
ATOM   4659 C  CG   . ASP A 1 303 ? 19.84200  -27.74500 -39.66000 1.000 27.19273  ? 303 ASP A CG   1 
ATOM   4660 O  OD1  . ASP A 1 303 ? 18.73100  -27.99400 -39.13400 1.000 29.67198  ? 303 ASP A OD1  1 
ATOM   4661 O  OD2  . ASP A 1 303 ? 20.77500  -28.57000 -39.67300 1.000 31.09583  ? 303 ASP A OD2  1 
ATOM   4662 H  H    A ASP A 1 303 ? 20.32200  -27.39400 -42.97000 0.370 33.32000  ? 303 ASP A H    1 
ATOM   4663 H  H    B ASP A 1 303 ? 20.32200  -27.39400 -42.97000 0.630 33.32000  ? 303 ASP A H    1 
ATOM   4664 H  HA   . ASP A 1 303 ? 18.39400  -26.15900 -41.57000 1.000 32.25000  ? 303 ASP A HA   1 
ATOM   4665 H  HB2  . ASP A 1 303 ? 21.00100  -26.25300 -40.42600 1.000 34.13000  ? 303 ASP A HB2  1 
ATOM   4666 H  HB3  . ASP A 1 303 ? 19.68800  -25.71200 -39.71200 1.000 34.13000  ? 303 ASP A HB3  1 
ATOM   4667 N  N    . VAL A 1 304 ? 19.09000  -23.90300 -42.28900 1.000 29.60355  ? 304 VAL A N    1 
ATOM   4668 C  CA   . VAL A 1 304 ? 19.50700  -22.61200 -42.81900 1.000 27.47435  ? 304 VAL A CA   1 
ATOM   4669 C  C    . VAL A 1 304 ? 19.26800  -21.53600 -41.76400 1.000 29.16929  ? 304 VAL A C    1 
ATOM   4670 O  O    . VAL A 1 304 ? 18.20200  -21.49500 -41.13900 1.000 29.92727  ? 304 VAL A O    1 
ATOM   4671 C  CB   . VAL A 1 304 ? 18.78100  -22.26100 -44.13300 1.000 27.47171  ? 304 VAL A CB   1 
ATOM   4672 C  CG1  . VAL A 1 304 ? 19.37100  -20.99300 -44.71700 1.000 31.45640  ? 304 VAL A CG1  1 
ATOM   4673 C  CG2  . VAL A 1 304 ? 18.89400  -23.39800 -45.14500 1.000 30.52998  ? 304 VAL A CG2  1 
ATOM   4674 H  H    . VAL A 1 304 ? 18.30700  -23.89800 -41.93500 1.000 35.52000  ? 304 VAL A H    1 
ATOM   4675 H  HA   . VAL A 1 304 ? 20.46000  -22.64300 -42.99700 1.000 32.97000  ? 304 VAL A HA   1 
ATOM   4676 H  HB   . VAL A 1 304 ? 17.84000  -22.12300 -43.94200 1.000 32.97000  ? 304 VAL A HB   1 
ATOM   4677 H  HG11 . VAL A 1 304 ? 19.01700  -20.86200 -45.61000 1.000 37.75000  ? 304 VAL A HG11 1 
ATOM   4678 H  HG12 . VAL A 1 304 ? 19.12900  -20.24300 -44.15200 1.000 37.75000  ? 304 VAL A HG12 1 
ATOM   4679 H  HG13 . VAL A 1 304 ? 20.33600  -21.08200 -44.75400 1.000 37.75000  ? 304 VAL A HG13 1 
ATOM   4680 H  HG21 . VAL A 1 304 ? 18.46400  -23.12900 -45.97200 1.000 36.63000  ? 304 VAL A HG21 1 
ATOM   4681 H  HG22 . VAL A 1 304 ? 19.83200  -23.58500 -45.30700 1.000 36.63000  ? 304 VAL A HG22 1 
ATOM   4682 H  HG23 . VAL A 1 304 ? 18.45700  -24.18600 -44.78600 1.000 36.63000  ? 304 VAL A HG23 1 
ATOM   4683 N  N    . PHE A 1 305 ? 20.25500  -20.67100 -41.57800 1.000 27.89282  ? 305 PHE A N    1 
ATOM   4684 C  CA   . PHE A 1 305 ? 20.20200  -19.56900 -40.62700 1.000 29.62724  ? 305 PHE A CA   1 
ATOM   4685 C  C    . PHE A 1 305 ? 20.08700  -18.26000 -41.38500 1.000 30.27731  ? 305 PHE A C    1 
ATOM   4686 O  O    . PHE A 1 305 ? 20.71900  -18.07600 -42.43300 1.000 31.05636  ? 305 PHE A O    1 
ATOM   4687 C  CB   . PHE A 1 305 ? 21.44600  -19.59100 -39.73500 1.000 27.78228  ? 305 PHE A CB   1 
ATOM   4688 C  CG   . PHE A 1 305 ? 21.51200  -20.81100 -38.87000 1.000 28.97189  ? 305 PHE A CG   1 
ATOM   4689 C  CD1  . PHE A 1 305 ? 21.96200  -22.01200 -39.37900 1.000 30.24047  ? 305 PHE A CD1  1 
ATOM   4690 C  CD2  . PHE A 1 305 ? 21.10000  -20.75700 -37.54900 1.000 30.88265  ? 305 PHE A CD2  1 
ATOM   4691 C  CE1  . PHE A 1 305 ? 22.00000  -23.14600 -38.59400 1.000 29.84568  ? 305 PHE A CE1  1 
ATOM   4692 C  CE2  . PHE A 1 305 ? 21.13800  -21.88900 -36.75500 1.000 31.40903  ? 305 PHE A CE2  1 
ATOM   4693 C  CZ   . PHE A 1 305 ? 21.57800  -23.07900 -37.27400 1.000 29.01927  ? 305 PHE A CZ   1 
ATOM   4694 H  H    . PHE A 1 305 ? 20.99800  -20.70300 -42.01000 1.000 33.47000  ? 305 PHE A H    1 
ATOM   4695 H  HA   . PHE A 1 305 ? 19.42400  -19.63900 -40.05300 1.000 35.55000  ? 305 PHE A HA   1 
ATOM   4696 H  HB2  . PHE A 1 305 ? 22.23800  -19.57600 -40.29500 1.000 33.34000  ? 305 PHE A HB2  1 
ATOM   4697 H  HB3  . PHE A 1 305 ? 21.43400  -18.81200 -39.15700 1.000 33.34000  ? 305 PHE A HB3  1 
ATOM   4698 H  HD1  . PHE A 1 305 ? 22.24400  -22.05800 -40.26400 1.000 36.29000  ? 305 PHE A HD1  1 
ATOM   4699 H  HD2  . PHE A 1 305 ? 20.79600  -19.95300 -37.19300 1.000 37.06000  ? 305 PHE A HD2  1 
ATOM   4700 H  HE1  . PHE A 1 305 ? 22.30700  -23.95000 -38.94800 1.000 35.81000  ? 305 PHE A HE1  1 
ATOM   4701 H  HE2  . PHE A 1 305 ? 20.86400  -21.84300 -35.86700 1.000 37.69000  ? 305 PHE A HE2  1 
ATOM   4702 H  HZ   . PHE A 1 305 ? 21.59400  -23.84100 -36.74100 1.000 34.82000  ? 305 PHE A HZ   1 
ATOM   4703 N  N    . TYR A 1 306 ? 19.22800  -17.38300 -40.88400 1.000 29.29825  ? 306 TYR A N    1 
ATOM   4704 C  CA   . TYR A 1 306 ? 18.98800  -16.08000 -41.48000 1.000 32.78025  ? 306 TYR A CA   1 
ATOM   4705 C  C    . TYR A 1 306 ? 19.11900  -14.98200 -40.43600 1.000 31.46430  ? 306 TYR A C    1 
ATOM   4706 O  O    . TYR A 1 306 ? 18.78800  -15.17700 -39.27000 1.000 31.99068  ? 306 TYR A O    1 
ATOM   4707 C  CB   . TYR A 1 306 ? 17.59200  -15.98800 -42.09500 1.000 33.73299  ? 306 TYR A CB   1 
ATOM   4708 C  CG   . TYR A 1 306 ? 17.25000  -17.04400 -43.11400 1.000 31.02477  ? 306 TYR A CG   1 
ATOM   4709 C  CD1  . TYR A 1 306 ? 16.80500  -18.30600 -42.73900 1.000 29.84568  ? 306 TYR A CD1  1 
ATOM   4710 C  CD2  . TYR A 1 306 ? 17.35100  -16.76700 -44.46100 1.000 33.82511  ? 306 TYR A CD2  1 
ATOM   4711 C  CE1  . TYR A 1 306 ? 16.47400  -19.26200 -43.69600 1.000 30.47207  ? 306 TYR A CE1  1 
ATOM   4712 C  CE2  . TYR A 1 306 ? 17.02500  -17.69800 -45.40500 1.000 35.29897  ? 306 TYR A CE2  1 
ATOM   4713 C  CZ   . TYR A 1 306 ? 16.59200  -18.93800 -45.03100 1.000 33.50402  ? 306 TYR A CZ   1 
ATOM   4714 O  OH   . TYR A 1 306 ? 16.28600  -19.82700 -46.03900 1.000 32.42494  ? 306 TYR A OH   1 
ATOM   4715 H  H    . TYR A 1 306 ? 18.75900  -17.52600 -40.17700 1.000 35.16000  ? 306 TYR A H    1 
ATOM   4716 H  HA   . TYR A 1 306 ? 19.65500  -15.93700 -42.17000 1.000 39.33000  ? 306 TYR A HA   1 
ATOM   4717 H  HB2  . TYR A 1 306 ? 16.94000  -16.05800 -41.37900 1.000 40.48000  ? 306 TYR A HB2  1 
ATOM   4718 H  HB3  . TYR A 1 306 ? 17.51000  -15.12700 -42.53500 1.000 40.48000  ? 306 TYR A HB3  1 
ATOM   4719 H  HD1  . TYR A 1 306 ? 16.72700  -18.51600 -41.83600 1.000 35.81000  ? 306 TYR A HD1  1 
ATOM   4720 H  HD2  . TYR A 1 306 ? 17.64800  -15.92800 -44.73200 1.000 40.59000  ? 306 TYR A HD2  1 
ATOM   4721 H  HE1  . TYR A 1 306 ? 16.17900  -20.10500 -43.43800 1.000 36.57000  ? 306 TYR A HE1  1 
ATOM   4722 H  HE2  . TYR A 1 306 ? 17.09900  -17.48600 -46.30800 1.000 42.36000  ? 306 TYR A HE2  1 
ATOM   4723 H  HH   . TYR A 1 306 ? 16.06500  -20.56800 -45.71100 1.000 38.91000  ? 306 TYR A HH   1 
ATOM   4724 N  N    . LYS A 1 307 ? 19.57600  -13.81400 -40.88400 1.000 38.07035  ? 307 LYS A N    1 
ATOM   4725 C  CA   . LYS A 1 307 ? 19.57600  -12.62200 -40.05100 1.000 35.78850  ? 307 LYS A CA   1 
ATOM   4726 C  C    . LYS A 1 307 ? 18.15300  -12.09500 -39.89100 1.000 36.81231  ? 307 LYS A C    1 
ATOM   4727 O  O    . LYS A 1 307 ? 17.32100  -12.18400 -40.79500 1.000 37.00180  ? 307 LYS A O    1 
ATOM   4728 C  CB   . LYS A 1 307 ? 20.43200  -11.51000 -40.66700 1.000 43.27624  ? 307 LYS A CB   1 
ATOM   4729 C  CG   . LYS A 1 307 ? 21.96200  -11.65600 -40.66700 1.000 57.19107  ? 307 LYS A CG   1 
ATOM   4730 C  CD   . LYS A 1 307 ? 22.64400  -11.25900 -39.34900 1.000 74.56684  ? 307 LYS A CD   1 
ATOM   4731 C  CE   . LYS A 1 307 ? 23.76400  -12.24300 -38.93500 1.000 78.79629  ? 307 LYS A CE   1 
ATOM   4732 N  NZ   . LYS A 1 307 ? 23.36100  -13.44200 -38.12200 1.000 46.27397  ? 307 LYS A NZ   1 
ATOM   4733 H  H    . LYS A 1 307 ? 19.89400  -13.68800 -41.67300 1.000 45.68000  ? 307 LYS A H    1 
ATOM   4734 H  HA   . LYS A 1 307 ? 19.94600  -12.85200 -39.18400 1.000 42.94000  ? 307 LYS A HA   1 
ATOM   4735 H  HB2  . LYS A 1 307 ? 20.16700  -11.42000 -41.59600 1.000 51.93000  ? 307 LYS A HB2  1 
ATOM   4736 H  HB3  . LYS A 1 307 ? 20.23600  -10.69100 -40.18500 1.000 51.93000  ? 307 LYS A HB3  1 
ATOM   4737 H  HG2  . LYS A 1 307 ? 22.18300  -12.58500 -40.84100 1.000 68.63000  ? 307 LYS A HG2  1 
ATOM   4738 H  HG3  . LYS A 1 307 ? 22.32600  -11.09200 -41.36600 1.000 68.63000  ? 307 LYS A HG3  1 
ATOM   4739 H  HD2  . LYS A 1 307 ? 23.04100  -10.37900 -39.45100 1.000 89.48000  ? 307 LYS A HD2  1 
ATOM   4740 H  HD3  . LYS A 1 307 ? 21.98100  -11.24300 -38.64100 1.000 89.48000  ? 307 LYS A HD3  1 
ATOM   4741 H  HE2  . LYS A 1 307 ? 24.18000  -12.58000 -39.74400 1.000 94.56000  ? 307 LYS A HE2  1 
ATOM   4742 H  HE3  . LYS A 1 307 ? 24.41400  -11.75200 -38.40800 1.000 94.56000  ? 307 LYS A HE3  1 
ATOM   4743 H  HZ1  . LYS A 1 307 ? 24.07500  -13.94200 -37.94200 1.000 55.53000  ? 307 LYS A HZ1  1 
ATOM   4744 H  HZ2  . LYS A 1 307 ? 22.99200  -13.18000 -37.35500 1.000 55.53000  ? 307 LYS A HZ2  1 
ATOM   4745 H  HZ3  . LYS A 1 307 ? 22.77100  -13.93200 -38.57300 1.000 55.53000  ? 307 LYS A HZ3  1 
ATOM   4746 N  N    . GLU A 1 308 ? 17.88200  -11.50600 -38.73500 1.000 34.50940  ? 308 GLU A N    1 
ATOM   4747 C  CA   . GLU A 1 308 ? 16.59600  -10.87500 -38.49500 1.000 32.98817  ? 308 GLU A CA   1 
ATOM   4748 C  C    . GLU A 1 308 ? 16.81600  -9.76800  -37.48000 1.000 34.60678  ? 308 GLU A C    1 
ATOM   4749 O  O    . GLU A 1 308 ? 17.87500  -9.67200  -36.85500 1.000 35.05947  ? 308 GLU A O    1 
ATOM   4750 C  CB   . GLU A 1 308 ? 15.57100  -11.91000 -38.02300 1.000 35.42530  ? 308 GLU A CB   1 
ATOM   4751 C  CG   . GLU A 1 308 ? 14.14800  -11.43400 -37.83200 1.000 35.09368  ? 308 GLU A CG   1 
ATOM   4752 C  CD   . GLU A 1 308 ? 13.57400  -10.73600 -39.04100 1.000 37.03076  ? 308 GLU A CD   1 
ATOM   4753 O  OE1  . GLU A 1 308 ? 13.77300  -9.50400  -39.16800 1.000 37.43080  ? 308 GLU A OE1  1 
ATOM   4754 O  OE2  . GLU A 1 308 ? 12.94200  -11.42500 -39.86300 1.000 38.85992  ? 308 GLU A OE2  1 
ATOM   4755 H  H    . GLU A 1 308 ? 18.42900  -11.45800 -38.07300 1.000 41.41000  ? 308 GLU A H    1 
ATOM   4756 H  HA   . GLU A 1 308 ? 16.24600  -10.47000 -39.30400 1.000 39.59000  ? 308 GLU A HA   1 
ATOM   4757 H  HB2  . GLU A 1 308 ? 15.54300  -12.62400 -38.68000 1.000 42.51000  ? 308 GLU A HB2  1 
ATOM   4758 H  HB3  . GLU A 1 308 ? 15.86800  -12.25800 -37.16800 1.000 42.51000  ? 308 GLU A HB3  1 
ATOM   4759 H  HG2  . GLU A 1 308 ? 13.58500  -12.19900 -37.63800 1.000 42.11000  ? 308 GLU A HG2  1 
ATOM   4760 H  HG3  . GLU A 1 308 ? 14.12500  -10.80800 -37.09100 1.000 42.11000  ? 308 GLU A HG3  1 
ATOM   4761 N  N    A ASN A 1 309 ? 15.84500  -8.86000  -37.42300 0.500 36.34646  ? 309 ASN A N    1 
ATOM   4762 N  N    B ASN A 1 309 ? 15.78900  -8.94000  -37.31400 0.500 36.37015  ? 309 ASN A N    1 
ATOM   4763 C  CA   A ASN A 1 309 ? 15.73900  -7.87000  -36.35900 0.500 38.09667  ? 309 ASN A CA   1 
ATOM   4764 C  CA   B ASN A 1 309 ? 15.70800  -7.98300  -36.21500 0.500 37.92560  ? 309 ASN A CA   1 
ATOM   4765 C  C    A ASN A 1 309 ? 14.27400  -7.83800  -35.94300 0.500 38.44935  ? 309 ASN A C    1 
ATOM   4766 C  C    B ASN A 1 309 ? 14.22700  -7.81900  -35.88400 0.500 38.44671  ? 309 ASN A C    1 
ATOM   4767 O  O    A ASN A 1 309 ? 13.88500  -8.36300  -34.89200 0.500 37.88086  ? 309 ASN A O    1 
ATOM   4768 O  O    B ASN A 1 309 ? 13.77600  -8.24400  -34.81400 0.500 37.92034  ? 309 ASN A O    1 
ATOM   4769 C  CB   A ASN A 1 309 ? 16.20900  -6.47500  -36.79500 0.500 39.17575  ? 309 ASN A CB   1 
ATOM   4770 C  CB   B ASN A 1 309 ? 16.38300  -6.66600  -36.58500 0.500 38.89677  ? 309 ASN A CB   1 
ATOM   4771 C  CG   A ASN A 1 309 ? 15.90400  -6.16000  -38.25900 0.500 39.88373  ? 309 ASN A CG   1 
ATOM   4772 C  CG   B ASN A 1 309 ? 16.24300  -5.60700  -35.50200 0.500 40.12586  ? 309 ASN A CG   1 
ATOM   4773 O  OD1  A ASN A 1 309 ? 14.75500  -6.20600  -38.70400 0.500 39.96269  ? 309 ASN A OD1  1 
ATOM   4774 O  OD1  B ASN A 1 309 ? 15.54600  -5.79500  -34.50200 0.500 43.25255  ? 309 ASN A OD1  1 
ATOM   4775 N  ND2  A ASN A 1 309 ? 16.93900  -5.79000  -39.00100 0.500 42.24191  ? 309 ASN A ND2  1 
ATOM   4776 N  ND2  B ASN A 1 309 ? 16.92600  -4.48300  -35.69500 0.500 44.15793  ? 309 ASN A ND2  1 
ATOM   4777 H  H    A ASN A 1 309 ? 15.21800  -8.79500  -38.00700 0.500 43.61000  ? 309 ASN A H    1 
ATOM   4778 H  H    B ASN A 1 309 ? 15.10800  -8.91100  -37.83900 0.500 43.65000  ? 309 ASN A H    1 
ATOM   4779 H  HA   A ASN A 1 309 ? 16.31700  -8.10700  -35.61700 0.500 45.72000  ? 309 ASN A HA   1 
ATOM   4780 H  HA   B ASN A 1 309 ? 16.18200  -8.28800  -35.42600 0.500 45.51000  ? 309 ASN A HA   1 
ATOM   4781 H  HB2  A ASN A 1 309 ? 15.76200  -5.80900  -36.24800 0.500 47.01000  ? 309 ASN A HB2  1 
ATOM   4782 H  HB2  B ASN A 1 309 ? 17.32900  -6.82500  -36.72900 0.500 46.68000  ? 309 ASN A HB2  1 
ATOM   4783 H  HB3  A ASN A 1 309 ? 17.16900  -6.41500  -36.67100 0.500 47.01000  ? 309 ASN A HB3  1 
ATOM   4784 H  HB3  B ASN A 1 309 ? 15.97700  -6.32000  -37.39600 0.500 46.68000  ? 309 ASN A HB3  1 
ATOM   4785 H  HD21 A ASN A 1 309 ? 16.82600  -5.60000  -39.83300 0.500 50.69000  ? 309 ASN A HD21 1 
ATOM   4786 H  HD21 B ASN A 1 309 ? 16.88500  -3.85000  -35.11500 0.500 52.99000  ? 309 ASN A HD21 1 
ATOM   4787 H  HD22 A ASN A 1 309 ? 17.72300  -5.73900  -38.65200 0.500 50.69000  ? 309 ASN A HD22 1 
ATOM   4788 H  HD22 B ASN A 1 309 ? 17.40900  -4.38900  -36.40000 0.500 52.99000  ? 309 ASN A HD22 1 
ATOM   4789 N  N    . SER A 1 310 ? 13.45200  -7.24700  -36.80800 1.000 38.58094  ? 310 SER A N    1 
ATOM   4790 C  CA   . SER A 1 310 ? 12.01700  -7.11700  -36.60600 1.000 40.29430  ? 310 SER A CA   1 
ATOM   4791 C  C    . SER A 1 310 ? 11.31700  -7.26400  -37.94700 1.000 41.74974  ? 310 SER A C    1 
ATOM   4792 O  O    . SER A 1 310 ? 11.64200  -6.55900  -38.90700 1.000 43.20781  ? 310 SER A O    1 
ATOM   4793 C  CB   . SER A 1 310 ? 11.67200  -5.76400  -35.97000 1.000 43.45521  ? 310 SER A CB   1 
ATOM   4794 O  OG   . SER A 1 310 ? 10.29400  -5.67800  -35.67900 1.000 50.40078  ? 310 SER A OG   1 
ATOM   4795 H  H    A SER A 1 310 ? 13.71600  -6.90100  -37.55000 0.500 46.30000  ? 310 SER A H    1 
ATOM   4796 H  H    B SER A 1 310 ? 13.73700  -6.93000  -37.55500 0.500 46.30000  ? 310 SER A H    1 
ATOM   4797 H  HA   . SER A 1 310 ? 11.70400  -7.82200  -36.01700 1.000 48.35000  ? 310 SER A HA   1 
ATOM   4798 H  HB2  . SER A 1 310 ? 12.17400  -5.66600  -35.14600 1.000 52.15000  ? 310 SER A HB2  1 
ATOM   4799 H  HB3  . SER A 1 310 ? 11.90800  -5.05600  -36.58900 1.000 52.15000  ? 310 SER A HB3  1 
ATOM   4800 H  HG   . SER A 1 310 ? 10.11700  -4.92700  -35.34600 1.000 60.48000  ? 310 SER A HG   1 
ATOM   4801 N  N    . TYR A 1 311 ? 10.35500  -8.17400  -38.00500 1.000 41.29969  ? 311 TYR A N    1 
ATOM   4802 C  CA   . TYR A 1 311 ? 9.55600   -8.40100  -39.19800 1.000 40.87859  ? 311 TYR A CA   1 
ATOM   4803 C  C    . TYR A 1 311 ? 8.08700   -8.37100  -38.80300 1.000 43.28151  ? 311 TYR A C    1 
ATOM   4804 O  O    . TYR A 1 311 ? 7.69900   -8.96200  -37.78700 1.000 41.39180  ? 311 TYR A O    1 
ATOM   4805 C  CB   . TYR A 1 311 ? 9.91900   -9.73700  -39.86200 1.000 37.98350  ? 311 TYR A CB   1 
ATOM   4806 C  CG   . TYR A 1 311 ? 8.93900   -10.15100 -40.92400 1.000 38.48619  ? 311 TYR A CG   1 
ATOM   4807 C  CD1  . TYR A 1 311 ? 9.05500   -9.66500  -42.22500 1.000 38.90203  ? 311 TYR A CD1  1 
ATOM   4808 C  CD2  . TYR A 1 311 ? 7.89000   -11.01400 -40.64000 1.000 37.66767  ? 311 TYR A CD2  1 
ATOM   4809 C  CE1  . TYR A 1 311 ? 8.16200   -10.02600 -43.20000 1.000 40.59434  ? 311 TYR A CE1  1 
ATOM   4810 C  CE2  . TYR A 1 311 ? 6.98300   -11.38300 -41.61800 1.000 36.84652  ? 311 TYR A CE2  1 
ATOM   4811 C  CZ   . TYR A 1 311 ? 7.12700   -10.87700 -42.90100 1.000 40.36010  ? 311 TYR A CZ   1 
ATOM   4812 O  OH   . TYR A 1 311 ? 6.24100   -11.22700 -43.89400 1.000 40.17850  ? 311 TYR A OH   1 
ATOM   4813 H  H    . TYR A 1 311 ? 10.14000  -8.68600  -37.34800 1.000 49.56000  ? 311 TYR A H    1 
ATOM   4814 H  HA   . TYR A 1 311 ? 9.71400   -7.69700  -39.84700 1.000 49.05000  ? 311 TYR A HA   1 
ATOM   4815 H  HB2  . TYR A 1 311 ? 10.79200  -9.65500  -40.27700 1.000 45.58000  ? 311 TYR A HB2  1 
ATOM   4816 H  HB3  . TYR A 1 311 ? 9.93600   -10.43000 -39.18500 1.000 45.58000  ? 311 TYR A HB3  1 
ATOM   4817 H  HD1  . TYR A 1 311 ? 9.75100   -9.08500  -42.43500 1.000 46.68000  ? 311 TYR A HD1  1 
ATOM   4818 H  HD2  . TYR A 1 311 ? 7.79500   -11.35000 -39.77800 1.000 45.20000  ? 311 TYR A HD2  1 
ATOM   4819 H  HE1  . TYR A 1 311 ? 8.25700   -9.69500  -44.06300 1.000 48.72000  ? 311 TYR A HE1  1 
ATOM   4820 H  HE2  . TYR A 1 311 ? 6.28400   -11.96400 -41.41700 1.000 44.22000  ? 311 TYR A HE2  1 
ATOM   4821 H  HH   . TYR A 1 311 ? 5.65400   -11.74500 -43.58600 1.000 48.21000  ? 311 TYR A HH   1 
ATOM   4822 N  N    . THR A 1 312 ? 7.28400   -7.66200  -39.59100 1.000 40.36010  ? 312 THR A N    1 
ATOM   4823 C  CA   . THR A 1 312 ? 5.83400   -7.70400  -39.48500 1.000 42.32876  ? 312 THR A CA   1 
ATOM   4824 C  C    . THR A 1 312 ? 5.23800   -7.98900  -40.85500 1.000 43.83420  ? 312 THR A C    1 
ATOM   4825 O  O    . THR A 1 312 ? 5.60700   -7.34500  -41.84300 1.000 46.00815  ? 312 THR A O    1 
ATOM   4826 C  CB   . THR A 1 312 ? 5.26400   -6.39500  -38.93200 1.000 43.82894  ? 312 THR A CB   1 
ATOM   4827 O  OG1  . THR A 1 312 ? 5.91200   -6.07200  -37.69500 1.000 50.06653  ? 312 THR A OG1  1 
ATOM   4828 C  CG2  . THR A 1 312 ? 3.77200   -6.53400  -38.71200 1.000 46.99511  ? 312 THR A CG2  1 
ATOM   4829 H  H    . THR A 1 312 ? 7.56600   -7.13600  -40.21000 1.000 48.43000  ? 312 THR A H    1 
ATOM   4830 H  HA   . THR A 1 312 ? 5.58400   -8.42100  -38.88200 1.000 50.80000  ? 312 THR A HA   1 
ATOM   4831 H  HB   . THR A 1 312 ? 5.41600   -5.67400  -39.56200 1.000 52.60000  ? 312 THR A HB   1 
ATOM   4832 H  HG1  . THR A 1 312 ? 5.59800   -5.35700  -37.38500 1.000 60.08000  ? 312 THR A HG1  1 
ATOM   4833 H  HG21 . THR A 1 312 ? 3.44800   -5.80100  -38.16600 1.000 56.40000  ? 312 THR A HG21 1 
ATOM   4834 H  HG22 . THR A 1 312 ? 3.30900   -6.52200  -39.56400 1.000 56.40000  ? 312 THR A HG22 1 
ATOM   4835 H  HG23 . THR A 1 312 ? 3.58000   -7.37200  -38.26100 1.000 56.40000  ? 312 THR A HG23 1 
ATOM   4836 N  N    . THR A 1 313 ? 4.31400   -8.94200  -40.90800 1.000 41.57341  ? 313 THR A N    1 
ATOM   4837 C  CA   . THR A 1 313 ? 3.69800   -9.32500  -42.16300 1.000 43.62365  ? 313 THR A CA   1 
ATOM   4838 C  C    . THR A 1 313 ? 2.86100   -8.18700  -42.74200 1.000 47.14513  ? 313 THR A C    1 
ATOM   4839 O  O    . THR A 1 313 ? 2.45800   -7.24200  -42.05200 1.000 46.28713  ? 313 THR A O    1 
ATOM   4840 C  CB   . THR A 1 313 ? 2.80000   -10.55000 -41.98100 1.000 43.39204  ? 313 THR A CB   1 
ATOM   4841 O  OG1  . THR A 1 313 ? 2.45400   -11.09300 -43.26300 1.000 46.26081  ? 313 THR A OG1  1 
ATOM   4842 C  CG2  . THR A 1 313 ? 1.51300   -10.18000 -41.25500 1.000 44.83169  ? 313 THR A CG2  1 
ATOM   4843 H  H    . THR A 1 313 ? 4.02800   -9.38100  -40.22600 1.000 49.89000  ? 313 THR A H    1 
ATOM   4844 H  HA   . THR A 1 313 ? 4.40500   -9.54400  -42.79000 1.000 52.35000  ? 313 THR A HA   1 
ATOM   4845 H  HB   . THR A 1 313 ? 3.27700   -11.21100 -41.45500 1.000 52.07000  ? 313 THR A HB   1 
ATOM   4846 H  HG1  . THR A 1 313 ? 1.94100   -11.75100 -43.16700 1.000 55.51000  ? 313 THR A HG1  1 
ATOM   4847 H  HG21 . THR A 1 313 ? 1.09800   -10.97700 -40.88800 1.000 53.80000  ? 313 THR A HG21 1 
ATOM   4848 H  HG22 . THR A 1 313 ? 1.70500   -9.56500  -40.53000 1.000 53.80000  ? 313 THR A HG22 1 
ATOM   4849 H  HG23 . THR A 1 313 ? 0.89400   -9.75800  -41.87100 1.000 53.80000  ? 313 THR A HG23 1 
ATOM   4850 N  N    . THR A 1 314 ? 2.58400   -8.30500  -44.03400 1.000 50.86136  ? 314 THR A N    1 
ATOM   4851 C  CA   . THR A 1 314 ? 1.60500   -7.46100  -44.69900 1.000 48.31632  ? 314 THR A CA   1 
ATOM   4852 C  C    . THR A 1 314 ? 0.33200   -8.21400  -45.04600 1.000 55.03818  ? 314 THR A C    1 
ATOM   4853 O  O    . THR A 1 314 ? -0.65200  -7.58500  -45.44700 1.000 54.66182  ? 314 THR A O    1 
ATOM   4854 C  CB   . THR A 1 314 ? 2.20900   -6.85200  -45.96900 1.000 47.81100  ? 314 THR A CB   1 
ATOM   4855 O  OG1  . THR A 1 314 ? 2.45800   -7.89300  -46.91900 1.000 50.49290  ? 314 THR A OG1  1 
ATOM   4856 C  CG2  . THR A 1 314 ? 3.50800   -6.13900  -45.64700 1.000 54.81710  ? 314 THR A CG2  1 
ATOM   4857 H  H    . THR A 1 314 ? 2.95800   -8.87700  -44.55600 1.000 61.03000  ? 314 THR A H    1 
ATOM   4858 H  HA   . THR A 1 314 ? 1.36500   -6.72400  -44.11600 1.000 57.98000  ? 314 THR A HA   1 
ATOM   4859 H  HB   . THR A 1 314 ? 1.59300   -6.20600  -46.34900 1.000 57.37000  ? 314 THR A HB   1 
ATOM   4860 H  HG1  . THR A 1 314 ? 2.78100   -7.56700  -47.62300 1.000 60.59000  ? 314 THR A HG1  1 
ATOM   4861 H  HG21 . THR A 1 314 ? 3.80300   -5.62500  -46.41500 1.000 65.78000  ? 314 THR A HG21 1 
ATOM   4862 H  HG22 . THR A 1 314 ? 3.37900   -5.53800  -44.89700 1.000 65.78000  ? 314 THR A HG22 1 
ATOM   4863 H  HG23 . THR A 1 314 ? 4.19400   -6.78600  -45.41900 1.000 65.78000  ? 314 THR A HG23 1 
ATOM   4864 N  N    . ILE A 1 315 ? 0.32200   -9.53600  -44.89900 1.000 51.26404  ? 315 ILE A N    1 
ATOM   4865 C  CA   . ILE A 1 315 ? -0.88200  -10.33400 -45.10200 1.000 52.40628  ? 315 ILE A CA   1 
ATOM   4866 C  C    . ILE A 1 315 ? -2.00000  -9.78700  -44.21800 1.000 56.77260  ? 315 ILE A C    1 
ATOM   4867 O  O    . ILE A 1 315 ? -1.90900  -9.80800  -42.98500 1.000 52.58788  ? 315 ILE A O    1 
ATOM   4868 C  CB   . ILE A 1 315 ? -0.59200  -11.81800 -44.80000 1.000 50.64028  ? 315 ILE A CB   1 
ATOM   4869 C  CG1  . ILE A 1 315 ? 0.42100   -12.37100 -45.80400 1.000 51.95097  ? 315 ILE A CG1  1 
ATOM   4870 C  CG2  . ILE A 1 315 ? -1.87800  -12.62900 -44.81900 1.000 53.78276  ? 315 ILE A CG2  1 
ATOM   4871 C  CD1  . ILE A 1 315 ? 0.82700   -13.81400 -45.55300 1.000 49.45330  ? 315 ILE A CD1  1 
ATOM   4872 H  H    . ILE A 1 315 ? 1.01100   -10.00100 -44.67900 1.000 61.52000  ? 315 ILE A H    1 
ATOM   4873 H  HA   . ILE A 1 315 ? -1.17600  -10.26100 -46.02300 1.000 62.89000  ? 315 ILE A HA   1 
ATOM   4874 H  HB   . ILE A 1 315 ? -0.21000  -11.88500 -43.91100 1.000 60.77000  ? 315 ILE A HB   1 
ATOM   4875 H  HG12 . ILE A 1 315 ? 0.03300   -12.32500 -46.69200 1.000 62.34000  ? 315 ILE A HG12 1 
ATOM   4876 H  HG13 . ILE A 1 315 ? 1.22400   -11.82800 -45.76400 1.000 62.34000  ? 315 ILE A HG13 1 
ATOM   4877 H  HG21 . ILE A 1 315 ? -1.66000  -13.57000 -44.72600 1.000 64.54000  ? 315 ILE A HG21 1 
ATOM   4878 H  HG22 . ILE A 1 315 ? -2.44100  -12.34600 -44.08200 1.000 64.54000  ? 315 ILE A HG22 1 
ATOM   4879 H  HG23 . ILE A 1 315 ? -2.33500  -12.47700 -45.66100 1.000 64.54000  ? 315 ILE A HG23 1 
ATOM   4880 H  HD11 . ILE A 1 315 ? 1.61200   -14.01800 -46.08500 1.000 59.34000  ? 315 ILE A HD11 1 
ATOM   4881 H  HD12 . ILE A 1 315 ? 1.02700   -13.92600 -44.61100 1.000 59.34000  ? 315 ILE A HD12 1 
ATOM   4882 H  HD13 . ILE A 1 315 ? 0.09400   -14.39700 -45.80700 1.000 59.34000  ? 315 ILE A HD13 1 
ATOM   4883 N  N    . LYS A 1 316 ? -3.06200  -9.27500  -44.84400 1.000 66.51324  ? 316 LYS A N    1 
ATOM   4884 C  CA   . LYS A 1 316 ? -4.23800  -8.82600  -44.11200 1.000 68.49769  ? 316 LYS A CA   1 
ATOM   4885 C  C    . LYS A 1 316 ? -5.24800  -9.96400  -44.13000 1.000 72.16392  ? 316 LYS A C    1 
ATOM   4886 O  O    . LYS A 1 316 ? -6.01200  -10.09000 -45.09900 1.000 76.38021  ? 316 LYS A O    1 
ATOM   4887 C  CB   . LYS A 1 316 ? -4.83600  -7.56100  -44.73700 1.000 58.52807  ? 316 LYS A CB   1 
ATOM   4888 H  H    . LYS A 1 316 ? -3.12200  -9.17900  -45.69700 1.000 79.81000  ? 316 LYS A H    1 
ATOM   4889 H  HA   . LYS A 1 316 ? -3.99600  -8.61300  -43.19700 1.000 82.20000  ? 316 LYS A HA   1 
ATOM   4890 N  N    . PRO A 1 317 ? -5.29500  -10.82200 -43.10500 1.000 64.72618  ? 317 PRO A N    1 
ATOM   4891 C  CA   . PRO A 1 317 ? -6.16300  -11.99600 -43.23400 1.000 72.12181  ? 317 PRO A CA   1 
ATOM   4892 C  C    . PRO A 1 317 ? -7.42700  -11.89900 -42.38700 1.000 71.92441  ? 317 PRO A C    1 
ATOM   4893 O  O    . PRO A 1 317 ? -8.49900  -11.67400 -42.95500 1.000 66.97908  ? 317 PRO A O    1 
ATOM   4894 C  CB   . PRO A 1 317 ? -5.25700  -13.14300 -42.76200 1.000 67.20016  ? 317 PRO A CB   1 
ATOM   4895 H  HA   . PRO A 1 317 ? -6.41800  -12.14300 -44.15800 1.000 86.55000  ? 317 PRO A HA   1 
HETATM 4896 ZN ZN   . ZN  B 2 .   ? -9.44500  -27.28000 -40.75100 1.000 43.03000  ? 401 ZN  A ZN   1 
HETATM 4897 C  C1   . MLI C 3 .   ? 30.56400  -39.21400 -39.59900 1.000 32.18000  ? 402 MLI A C1   1 
HETATM 4898 C  C2   . MLI C 3 .   ? 31.61100  -39.57200 -40.64900 1.000 35.82000  ? 402 MLI A C2   1 
HETATM 4899 C  C3   . MLI C 3 .   ? 30.26400  -37.73200 -39.42800 1.000 30.39000  ? 402 MLI A C3   1 
HETATM 4900 O  O6   . MLI C 3 .   ? 32.37200  -38.69800 -41.04300 1.000 31.42000  ? 402 MLI A O6   1 
HETATM 4901 O  O7   . MLI C 3 .   ? 31.65300  -40.73100 -41.04700 1.000 36.05000  ? 402 MLI A O7   1 
HETATM 4902 O  O8   . MLI C 3 .   ? 29.18500  -37.31400 -39.81300 1.000 30.81000  ? 402 MLI A O8   1 
HETATM 4903 O  O9   . MLI C 3 .   ? 31.08900  -37.03600 -38.87200 1.000 29.69000  ? 402 MLI A O9   1 
HETATM 4904 H  H11  . MLI C 3 .   ? 29.73400  -39.66900 -39.82900 1.000 38.61000  ? 402 MLI A H11  1 
HETATM 4905 H  H12  . MLI C 3 .   ? 30.86000  -39.56200 -38.74100 1.000 38.61000  ? 402 MLI A H12  1 
HETATM 4906 C  C1   . PEG D 4 .   ? 19.73500  -35.62500 -40.86800 1.000 32.75000  ? 403 PEG A C1   1 
HETATM 4907 O  O1   . PEG D 4 .   ? 19.91200  -34.25000 -41.04200 1.000 31.65000  ? 403 PEG A O1   1 
HETATM 4908 C  C2   . PEG D 4 .   ? 20.99400  -36.30500 -40.46800 1.000 47.39000  ? 403 PEG A C2   1 
HETATM 4909 O  O2   . PEG D 4 .   ? 20.94500  -36.68300 -39.09900 1.000 46.24000  ? 403 PEG A O2   1 
HETATM 4910 C  C3   . PEG D 4 .   ? 21.64500  -37.89600 -38.84800 1.000 42.00000  ? 403 PEG A C3   1 
HETATM 4911 C  C4   . PEG D 4 .   ? 22.59300  -37.71200 -37.70800 1.000 36.79000  ? 403 PEG A C4   1 
HETATM 4912 O  O4   . PEG D 4 .   ? 23.20300  -38.92800 -37.32500 1.000 29.18000  ? 403 PEG A O4   1 
HETATM 4913 H  H11  . PEG D 4 .   ? 19.41200  -36.01400 -41.70900 1.000 39.30000  ? 403 PEG A H11  1 
HETATM 4914 H  H12  . PEG D 4 .   ? 19.05400  -35.77800 -40.18100 1.000 39.30000  ? 403 PEG A H12  1 
HETATM 4915 H  HO1  . PEG D 4 .   ? 20.47400  -34.11500 -41.66200 1.000 37.98000  ? 403 PEG A HO1  1 
HETATM 4916 H  H21  . PEG D 4 .   ? 21.75400  -35.70300 -40.61300 1.000 56.87000  ? 403 PEG A H21  1 
HETATM 4917 H  H22  . PEG D 4 .   ? 21.12200  -37.10200 -41.02400 1.000 56.87000  ? 403 PEG A H22  1 
HETATM 4918 H  H31  . PEG D 4 .   ? 21.00500  -38.60900 -38.63500 1.000 50.40000  ? 403 PEG A H31  1 
HETATM 4919 H  H32  . PEG D 4 .   ? 22.14500  -38.16500 -39.64800 1.000 50.40000  ? 403 PEG A H32  1 
HETATM 4920 H  H41  . PEG D 4 .   ? 23.28900  -37.07400 -37.97000 1.000 44.15000  ? 403 PEG A H41  1 
HETATM 4921 H  H42  . PEG D 4 .   ? 22.10900  -37.33900 -36.94200 1.000 44.15000  ? 403 PEG A H42  1 
HETATM 4922 H  HO4  . PEG D 4 .   ? 23.43200  -39.35300 -38.01900 1.000 35.01000  ? 403 PEG A HO4  1 
HETATM 4923 C  C1   . MLI E 3 .   ? 16.17000  -17.06400 -49.50000 1.000 52.63000  ? 404 MLI A C1   1 
HETATM 4924 C  C2   . MLI E 3 .   ? 16.04800  -16.92500 -51.01200 1.000 61.97000  ? 404 MLI A C2   1 
HETATM 4925 C  C3   . MLI E 3 .   ? 14.95500  -17.79700 -48.96400 1.000 47.00000  ? 404 MLI A C3   1 
HETATM 4926 O  O6   . MLI E 3 .   ? 15.53800  -15.89100 -51.46300 1.000 56.89000  ? 404 MLI A O6   1 
HETATM 4927 O  O7   . MLI E 3 .   ? 16.43500  -17.87100 -51.71600 1.000 57.25000  ? 404 MLI A O7   1 
HETATM 4928 O  O8   . MLI E 3 .   ? 14.36900  -18.53700 -49.74800 1.000 44.61000  ? 404 MLI A O8   1 
HETATM 4929 O  O9   . MLI E 3 .   ? 14.61100  -17.60500 -47.79200 1.000 38.98000  ? 404 MLI A O9   1 
HETATM 4930 H  H11  . MLI E 3 .   ? 16.22300  -16.18100 -49.09500 1.000 63.15000  ? 404 MLI A H11  1 
HETATM 4931 H  H12  . MLI E 3 .   ? 16.97600  -17.56800 -49.28200 1.000 63.15000  ? 404 MLI A H12  1 
HETATM 4932 NA NA   . NA  F 5 .   ? 27.75600  -15.50200 -32.00300 1.000 43.76000  ? 405 NA  A NA   1 
HETATM 4933 NA NA   . NA  G 5 .   ? 16.93600  -19.43300 -21.91300 1.000 40.06000  ? 406 NA  A NA   1 
HETATM 4934 CL CL   . CL  H 6 .   ? 28.33900  -16.11100 -24.31300 1.000 34.81000  ? 407 CL  A CL   1 
HETATM 4935 CL CL   . CL  I 6 .   ? 21.16100  -22.18400 -18.69400 1.000 35.56000  ? 408 CL  A CL   1 
HETATM 4936 O  O    . HOH J 7 .   ? 36.76000  -15.00000 -35.92600 1.000 43.73000  ? 501 HOH A O    1 
HETATM 4937 O  O    . HOH J 7 .   ? 42.25200  -22.07400 -33.53100 1.000 41.62000  ? 502 HOH A O    1 
HETATM 4938 O  O    . HOH J 7 .   ? 14.383    -16.496   -18.260   1.000 35.61000  ? 503 HOH A O    1 
HETATM 4939 O  O    . HOH J 7 .   ? 10.229    -23.129   -24.363   1.000 39.00000  ? 504 HOH A O    1 
HETATM 4940 O  O    . HOH J 7 .   ? 21.15100  -36.44000 -47.15100 1.000 42.36000  ? 505 HOH A O    1 
HETATM 4941 O  O    . HOH J 7 .   ? 0.92600   -25.55500 -35.82600 1.000 44.51000  ? 506 HOH A O    1 
HETATM 4942 O  O    . HOH J 7 .   ? 31.83700  -21.76700 -2.56200  1.000 41.98000  ? 507 HOH A O    1 
HETATM 4943 O  O    . HOH J 7 .   ? 32.99300  -39.73800 -13.15500 1.000 39.79000  ? 508 HOH A O    1 
HETATM 4944 O  O    . HOH J 7 .   ? 23.43900  -33.93500 -8.85200  1.000 38.30000  ? 509 HOH A O    1 
HETATM 4945 O  O    . HOH J 7 .   ? 36.60100  -41.54000 -21.31200 1.000 40.52000  ? 510 HOH A O    1 
HETATM 4946 O  O    . HOH J 7 .   ? 14.47300  -20.99300 -51.14200 1.000 46.01000  ? 511 HOH A O    1 
HETATM 4947 O  O    . HOH J 7 .   ? 14.99100  -35.79400 -49.17900 1.000 43.73000  ? 512 HOH A O    1 
HETATM 4948 O  O    . HOH J 7 .   ? 29.74600  -36.95700 -30.63000 1.000 27.08000  ? 513 HOH A O    1 
HETATM 4949 O  O    . HOH J 7 .   ? 4.39100   -13.05600 -43.43200 1.000 38.42000  ? 514 HOH A O    1 
HETATM 4950 O  O    . HOH J 7 .   ? -2.02200  -11.61300 -41.05500 1.000 53.20000  ? 515 HOH A O    1 
HETATM 4951 O  O    . HOH J 7 .   ? 51.83400  -42.59800 -4.30100  1.000 48.91000  ? 516 HOH A O    1 
HETATM 4952 O  O    . HOH J 7 .   ? 26.69400  -30.84900 -52.22200 1.000 41.71000  ? 517 HOH A O    1 
HETATM 4953 O  O    . HOH J 7 .   ? 32.25100  -11.08000 -42.02000 1.000 54.06000  ? 518 HOH A O    1 
HETATM 4954 O  O    . HOH J 7 .   ? 53.94900  -41.11300 9.84100   1.000 53.43000  ? 519 HOH A O    1 
HETATM 4955 O  O    . HOH J 7 .   ? 44.30900  -28.36400 -30.39000 1.000 45.01000  ? 520 HOH A O    1 
HETATM 4956 O  O    . HOH J 7 .   ? 33.29700  -17.37800 -14.82400 1.000 39.45000  ? 521 HOH A O    1 
HETATM 4957 O  O    . HOH J 7 .   ? 27.48400  -33.14700 -46.59300 1.000 33.17000  ? 522 HOH A O    1 
HETATM 4958 O  O    . HOH J 7 .   ? 39.53200  -17.08900 -54.11100 1.000 39.58000  ? 523 HOH A O    1 
HETATM 4959 O  O    . HOH J 7 .   ? 22.38800  -12.89400 -35.75400 1.000 34.59000  ? 524 HOH A O    1 
HETATM 4960 O  O    . HOH J 7 .   ? 34.54800  -37.34100 -7.18900  1.000 33.31000  ? 525 HOH A O    1 
HETATM 4961 O  O    . HOH J 7 .   ? 30.15000  -29.40200 -51.34500 1.000 46.83000  ? 526 HOH A O    1 
HETATM 4962 O  O    . HOH J 7 .   ? 34.86600  -25.44600 -18.02800 1.000 43.11000  ? 527 HOH A O    1 
HETATM 4963 O  O    . HOH J 7 .   ? 30.99100  -21.76700 -9.56200  1.000 29.28000  ? 528 HOH A O    1 
HETATM 4964 O  O    . HOH J 7 .   ? 26.47200  -32.40400 -11.39500 1.000 33.35000  ? 529 HOH A O    1 
HETATM 4965 O  O    . HOH J 7 .   ? 31.75600  -14.96300 -40.92600 1.000 42.68000  ? 530 HOH A O    1 
HETATM 4966 O  O    . HOH J 7 .   ? 23.20200  -20.84100 -55.66000 1.000 42.55000  ? 531 HOH A O    1 
HETATM 4967 O  O    . HOH J 7 .   ? -5.91100  -22.16400 -45.69700 1.000 51.55000  ? 532 HOH A O    1 
HETATM 4968 O  O    . HOH J 7 .   ? 26.74200  -14.52700 -43.75500 1.000 38.29000  ? 533 HOH A O    1 
HETATM 4969 O  O    . HOH J 7 .   ? 41.01900  -16.46500 -37.72600 1.000 46.40000  ? 534 HOH A O    1 
HETATM 4970 O  O    . HOH J 7 .   ? 36.58800  -41.95200 -23.63200 1.000 42.99000  ? 535 HOH A O    1 
HETATM 4971 O  O    . HOH J 7 .   ? 51.05500  -32.59400 2.34000   1.000 49.07000  ? 536 HOH A O    1 
HETATM 4972 O  O    . HOH J 7 .   ? 33.676    -42.244   -41.835   1.000 41.27000  ? 537 HOH A O    1 
HETATM 4973 O  O    . HOH J 7 .   ? 13.01600  -10.42000 -42.31000 1.000 42.45000  ? 538 HOH A O    1 
HETATM 4974 O  O    . HOH J 7 .   ? 24.47700  -39.55600 -21.56200 1.000 48.54000  ? 539 HOH A O    1 
HETATM 4975 O  O    . HOH J 7 .   ? 26.33200  -29.85200 -11.15700 1.000 43.25000  ? 540 HOH A O    1 
HETATM 4976 O  O    . HOH J 7 .   ? 31.27600  -42.91400 -28.32900 1.000 43.48000  ? 541 HOH A O    1 
HETATM 4977 O  O    . HOH J 7 .   ? 26.66700  -12.98500 -48.57200 1.000 40.27000  ? 542 HOH A O    1 
HETATM 4978 O  O    . HOH J 7 .   ? 41.92000  -18.76700 -25.26800 1.000 50.07000  ? 543 HOH A O    1 
HETATM 4979 O  O    . HOH J 7 .   ? 41.48300  -28.40000 -17.18300 1.000 42.42000  ? 544 HOH A O    1 
HETATM 4980 O  O    . HOH J 7 .   ? 42.85600  -23.11800 -41.95300 1.000 35.49000  ? 545 HOH A O    1 
HETATM 4981 O  O    . HOH J 7 .   ? 15.59900  -29.83700 -46.77900 1.000 34.39000  ? 546 HOH A O    1 
HETATM 4982 O  O    . HOH J 7 .   ? 15.47900  -17.80100 -23.19100 1.000 37.06000  ? 547 HOH A O    1 
HETATM 4983 O  O    . HOH J 7 .   ? 37.95500  -17.43400 -34.77300 1.000 38.53000  ? 548 HOH A O    1 
HETATM 4984 O  O    . HOH J 7 .   ? 34.61600  -40.55700 -16.99500 1.000 44.27000  ? 549 HOH A O    1 
HETATM 4985 O  O    . HOH J 7 .   ? 20.44900  -30.98800 -38.59200 1.000 30.00000  ? 550 HOH A O    1 
HETATM 4986 O  O    . HOH J 7 .   ? 41.579    -20.134   -9.378    1.000 29.34000  ? 551 HOH A O    1 
HETATM 4987 O  O    . HOH J 7 .   ? 6.23100   -27.18400 -42.58900 1.000 42.89000  ? 552 HOH A O    1 
HETATM 4988 O  O    . HOH J 7 .   ? 14.11600  -30.21100 -29.64200 1.000 45.30000  ? 553 HOH A O    1 
HETATM 4989 O  O    . HOH J 7 .   ? 36.50100  -31.34300 -2.90600  1.000 43.15000  ? 554 HOH A O    1 
HETATM 4990 O  O    . HOH J 7 .   ? 22.550    -38.629   -18.554   1.000 44.98000  ? 555 HOH A O    1 
HETATM 4991 O  O    . HOH J 7 .   ? 0.64600   -6.78600  -40.13200 1.000 48.76000  ? 556 HOH A O    1 
HETATM 4992 O  O    . HOH J 7 .   ? 21.29500  -14.28700 -26.73500 1.000 36.72000  ? 557 HOH A O    1 
HETATM 4993 O  O    . HOH J 7 .   ? 16.30400  -22.17000 -53.02800 1.000 41.81000  ? 558 HOH A O    1 
HETATM 4994 O  O    . HOH J 7 .   ? 36.59600  -22.44900 -15.65000 1.000 36.45000  ? 559 HOH A O    1 
HETATM 4995 O  O    . HOH J 7 .   ? 37.67200  -43.03700 -17.52300 1.000 46.97000  ? 560 HOH A O    1 
HETATM 4996 O  O    . HOH J 7 .   ? 38.66200  -27.32500 -17.85600 1.000 38.55000  ? 561 HOH A O    1 
HETATM 4997 O  O    . HOH J 7 .   ? 24.89600  -24.13800 -40.32700 1.000 30.55000  ? 562 HOH A O    1 
HETATM 4998 O  O    . HOH J 7 .   ? 15.32400  -8.49100  -32.62600 1.000 46.97000  ? 563 HOH A O    1 
HETATM 4999 O  O    . HOH J 7 .   ? 34.87100  -35.02300 -45.47600 1.000 34.88000  ? 564 HOH A O    1 
HETATM 5000 O  O    . HOH J 7 .   ? 20.51000  -13.52200 -29.08300 1.000 41.47000  ? 565 HOH A O    1 
HETATM 5001 O  O    . HOH J 7 .   ? 26.76200  -38.33800 -39.24100 1.000 32.96000  ? 566 HOH A O    1 
HETATM 5002 O  O    . HOH J 7 .   ? 18.28700  -20.66400 -20.48300 1.000 35.72000  ? 567 HOH A O    1 
HETATM 5003 O  O    . HOH J 7 .   ? 36.97600  -15.33600 -52.48200 1.000 42.70000  ? 568 HOH A O    1 
HETATM 5004 O  O    . HOH J 7 .   ? 3.69100   -17.87200 -25.70300 1.000 46.65000  ? 569 HOH A O    1 
HETATM 5005 O  O    . HOH J 7 .   ? 37.39800  -15.13200 -33.52200 1.000 43.85000  ? 570 HOH A O    1 
HETATM 5006 O  O    . HOH J 7 .   ? 34.30900  -42.92900 -37.79600 1.000 39.99000  ? 571 HOH A O    1 
HETATM 5007 O  O    . HOH J 7 .   ? 43.25200  -24.63700 -11.32600 1.000 39.93000  ? 572 HOH A O    1 
HETATM 5008 O  O    . HOH J 7 .   ? 32.26700  -25.40500 -52.74500 1.000 34.48000  ? 573 HOH A O    1 
HETATM 5009 O  O    . HOH J 7 .   ? 37.07700  -26.05100 0.75500   1.000 35.79000  ? 574 HOH A O    1 
HETATM 5010 O  O    . HOH J 7 .   ? 17.63900  -30.60500 -39.62100 1.000 30.92000  ? 575 HOH A O    1 
HETATM 5011 O  O    . HOH J 7 .   ? 40.77100  -24.70200 0.73500   1.000 32.51000  ? 576 HOH A O    1 
HETATM 5012 O  O    . HOH J 7 .   ? 4.47400   -26.75600 -38.58400 1.000 40.29000  ? 577 HOH A O    1 
HETATM 5013 O  O    . HOH J 7 .   ? 17.63300  -20.53000 -48.31500 1.000 39.06000  ? 578 HOH A O    1 
HETATM 5014 O  O    . HOH J 7 .   ? 8.45500   -21.83900 -34.76300 1.000 43.08000  ? 579 HOH A O    1 
HETATM 5015 O  O    . HOH J 7 .   ? 17.54800  -7.98700  -40.46400 1.000 46.85000  ? 580 HOH A O    1 
HETATM 5016 O  O    . HOH J 7 .   ? 40.30400  -46.57400 -6.38200  1.000 50.26000  ? 581 HOH A O    1 
HETATM 5017 O  O    . HOH J 7 .   ? 24.91700  -18.90000 -12.63100 1.000 32.47000  ? 582 HOH A O    1 
HETATM 5018 O  O    . HOH J 7 .   ? 30.13600  -15.23000 -31.39300 1.000 39.28000  ? 583 HOH A O    1 
HETATM 5019 O  O    . HOH J 7 .   ? 42.29600  -30.68500 -13.67600 1.000 32.90000  ? 584 HOH A O    1 
HETATM 5020 O  O    . HOH J 7 .   ? 6.89900   -6.82900  -44.17100 1.000 51.03000  ? 585 HOH A O    1 
HETATM 5021 O  O    . HOH J 7 .   ? 39.08100  -39.42000 -19.22500 1.000 37.90000  ? 586 HOH A O    1 
HETATM 5022 O  O    . HOH J 7 .   ? 31.22900  -15.79400 -17.14800 1.000 42.03000  ? 587 HOH A O    1 
HETATM 5023 O  O    . HOH J 7 .   ? 31.41300  -37.73800 -22.28900 1.000 31.09000  ? 588 HOH A O    1 
HETATM 5024 O  O    . HOH J 7 .   ? 51.92400  -27.51100 -9.00400  1.000 47.59000  ? 589 HOH A O    1 
HETATM 5025 O  O    . HOH J 7 .   ? 15.08400  -25.18800 -36.70300 1.000 31.02000  ? 590 HOH A O    1 
HETATM 5026 O  O    . HOH J 7 .   ? 27.81000  -43.34300 -26.24000 1.000 50.71000  ? 591 HOH A O    1 
HETATM 5027 O  O    . HOH J 7 .   ? 44.33400  -28.62000 -26.07400 1.000 48.71000  ? 592 HOH A O    1 
HETATM 5028 O  O    . HOH J 7 .   ? 43.74200  -24.26400 -30.88500 1.000 45.28000  ? 593 HOH A O    1 
HETATM 5029 O  O    . HOH J 7 .   ? 33.16500  -15.11800 -19.95700 1.000 43.66000  ? 594 HOH A O    1 
HETATM 5030 O  O    . HOH J 7 .   ? 42.46000  -38.68600 2.37300   1.000 47.26000  ? 595 HOH A O    1 
HETATM 5031 O  O    . HOH J 7 .   ? -7.96400  -24.98200 -45.47600 1.000 51.09000  ? 596 HOH A O    1 
HETATM 5032 O  O    . HOH J 7 .   ? 41.27200  -25.02700 -45.48700 1.000 31.73000  ? 597 HOH A O    1 
HETATM 5033 O  O    . HOH J 7 .   ? 34.92800  -32.17900 -48.38400 1.000 36.92000  ? 598 HOH A O    1 
HETATM 5034 O  O    . HOH J 7 .   ? 31.48600  -15.72700 -24.31100 1.000 36.14000  ? 599 HOH A O    1 
HETATM 5035 O  O    . HOH J 7 .   ? 20.83700  -47.02000 -36.84300 1.000 49.39000  ? 600 HOH A O    1 
HETATM 5036 O  O    . HOH J 7 .   ? 14.36700  -28.80900 -51.26100 1.000 33.58000  ? 601 HOH A O    1 
HETATM 5037 O  O    . HOH J 7 .   ? 35.16700  -26.03700 -15.66800 1.000 35.75000  ? 602 HOH A O    1 
HETATM 5038 O  O    . HOH J 7 .   ? 33.25500  -18.00600 -55.94400 1.000 39.46000  ? 603 HOH A O    1 
HETATM 5039 O  O    . HOH J 7 .   ? 40.85100  -35.21600 -40.25100 1.000 32.38000  ? 604 HOH A O    1 
HETATM 5040 O  O    . HOH J 7 .   ? -5.79400  -32.25900 -47.50800 1.000 37.86000  ? 605 HOH A O    1 
HETATM 5041 O  O    . HOH J 7 .   ? 8.44700   -5.03400  -37.66600 1.000 50.23000  ? 606 HOH A O    1 
HETATM 5042 O  O    . HOH J 7 .   ? 34.01100  -41.94600 -26.44000 1.000 44.64000  ? 607 HOH A O    1 
HETATM 5043 O  O    . HOH J 7 .   ? 25.83300  -40.92200 -24.72800 1.000 36.41000  ? 608 HOH A O    1 
HETATM 5044 O  O    . HOH J 7 .   ? 28.69400  -37.04200 -22.73400 1.000 32.71000  ? 609 HOH A O    1 
HETATM 5045 O  O    . HOH J 7 .   ? 34.90700  -29.37600 -1.02200  1.000 43.36000  ? 610 HOH A O    1 
HETATM 5046 O  O    . HOH J 7 .   ? 8.99900   -27.12100 -28.13500 1.000 49.87000  ? 611 HOH A O    1 
HETATM 5047 O  O    . HOH J 7 .   ? 38.11400  -39.88500 -21.87400 1.000 34.14000  ? 612 HOH A O    1 
HETATM 5048 O  O    . HOH J 7 .   ? 29.01200  -32.12700 -50.42700 1.000 36.18000  ? 613 HOH A O    1 
HETATM 5049 O  O    . HOH J 7 .   ? 35.04400  -31.73600 -38.31800 1.000 27.92000  ? 614 HOH A O    1 
HETATM 5050 O  O    . HOH J 7 .   ? 40.24900  -20.71800 -14.24200 1.000 45.36000  ? 615 HOH A O    1 
HETATM 5051 O  O    . HOH J 7 .   ? 24.16600  -13.13600 -46.75300 1.000 41.44000  ? 616 HOH A O    1 
HETATM 5052 O  O    . HOH J 7 .   ? 39.07100  -45.05300 -13.84700 1.000 51.41000  ? 617 HOH A O    1 
HETATM 5053 O  O    . HOH J 7 .   ? 26.43500  -37.08500 -36.92500 1.000 30.86000  ? 618 HOH A O    1 
HETATM 5054 O  O    . HOH J 7 .   ? 36.77900  -23.65400 -25.18500 1.000 29.77000  ? 619 HOH A O    1 
HETATM 5055 O  O    . HOH J 7 .   ? 35.08700  -16.22100 -34.03300 1.000 42.62000  ? 620 HOH A O    1 
HETATM 5056 O  O    . HOH J 7 .   ? 27.09800  -13.49400 -39.55900 1.000 36.27000  ? 621 HOH A O    1 
HETATM 5057 O  O    . HOH J 7 .   ? 35.04000  -25.63900 -7.58800  1.000 31.08000  ? 622 HOH A O    1 
HETATM 5058 O  O    . HOH J 7 .   ? 12.885    -18.538   -20.686   1.000 43.67000  ? 623 HOH A O    1 
HETATM 5059 O  O    . HOH J 7 .   ? 49.53700  -37.94700 -13.75300 1.000 47.05000  ? 624 HOH A O    1 
HETATM 5060 O  O    . HOH J 7 .   ? 42.23000  -22.05500 -11.14100 1.000 30.64000  ? 625 HOH A O    1 
HETATM 5061 O  O    . HOH J 7 .   ? 39.81600  -38.97600 -29.57400 1.000 36.81000  ? 626 HOH A O    1 
HETATM 5062 O  O    . HOH J 7 .   ? 34.55200  -13.92800 -45.59000 1.000 42.49000  ? 627 HOH A O    1 
HETATM 5063 O  O    . HOH J 7 .   ? -4.54600  -23.87100 -46.81100 1.000 53.16000  ? 628 HOH A O    1 
HETATM 5064 O  O    . HOH J 7 .   ? 28.68300  -34.12400 -12.01700 1.000 31.26000  ? 629 HOH A O    1 
HETATM 5065 O  O    . HOH J 7 .   ? -0.08800  -29.62600 -38.83400 1.000 48.43000  ? 630 HOH A O    1 
HETATM 5066 O  O    . HOH J 7 .   ? 6.780     -27.941   -37.329   1.000 40.65000  ? 631 HOH A O    1 
HETATM 5067 O  O    . HOH J 7 .   ? 28.26000  -14.91400 -41.69100 1.000 34.61000  ? 632 HOH A O    1 
HETATM 5068 O  O    . HOH J 7 .   ? 23.21800  -40.62500 -31.46100 1.000 45.99000  ? 633 HOH A O    1 
HETATM 5069 O  O    . HOH J 7 .   ? 27.66600  -39.66400 -46.49300 1.000 39.98000  ? 634 HOH A O    1 
HETATM 5070 O  O    . HOH J 7 .   ? 42.34400  -44.10600 -13.35800 1.000 40.93000  ? 635 HOH A O    1 
HETATM 5071 O  O    . HOH J 7 .   ? 32.46800  -36.69500 -31.39900 1.000 28.82000  ? 636 HOH A O    1 
HETATM 5072 O  O    . HOH J 7 .   ? 41.37600  -36.91600 -29.49700 1.000 39.95000  ? 637 HOH A O    1 
HETATM 5073 O  O    . HOH J 7 .   ? -1.13400  -15.24400 -29.83000 1.000 47.17000  ? 638 HOH A O    1 
HETATM 5074 O  O    . HOH J 7 .   ? 30.81300  -23.26900 -51.91800 1.000 34.35000  ? 639 HOH A O    1 
HETATM 5075 O  O    . HOH J 7 .   ? 28.90500  -35.81800 -37.22900 1.000 28.45000  ? 640 HOH A O    1 
HETATM 5076 O  O    . HOH J 7 .   ? -10.87900 -35.35800 -42.88100 1.000 45.69000  ? 641 HOH A O    1 
HETATM 5077 O  O    . HOH J 7 .   ? 42.52300  -25.71100 -42.43700 1.000 30.89000  ? 642 HOH A O    1 
HETATM 5078 O  O    . HOH J 7 .   ? 41.25900  -17.11500 -40.83800 1.000 38.46000  ? 643 HOH A O    1 
HETATM 5079 O  O    . HOH J 7 .   ? 32.29300  -14.46500 -26.51400 1.000 40.41000  ? 644 HOH A O    1 
HETATM 5080 O  O    . HOH J 7 .   ? 26.40600  -33.95000 -51.28700 1.000 42.49000  ? 645 HOH A O    1 
HETATM 5081 O  O    . HOH J 7 .   ? 25.40300  -29.42100 -8.66300  1.000 37.18000  ? 646 HOH A O    1 
HETATM 5082 O  O    . HOH J 7 .   ? 33.48000  -34.97800 -4.38200  1.000 43.87000  ? 647 HOH A O    1 
HETATM 5083 O  O    . HOH J 7 .   ? 34.28100  -22.90800 -19.02200 1.000 29.13000  ? 648 HOH A O    1 
HETATM 5084 O  O    . HOH J 7 .   ? 12.51200  -32.50400 -46.85200 1.000 38.31000  ? 649 HOH A O    1 
HETATM 5085 O  O    . HOH J 7 .   ? 16.54500  -29.42600 -26.75300 1.000 49.07000  ? 650 HOH A O    1 
HETATM 5086 O  O    . HOH J 7 .   ? 30.89700  -42.77900 -39.26600 1.000 47.35000  ? 651 HOH A O    1 
HETATM 5087 O  O    . HOH J 7 .   ? 30.19200  -28.52900 1.88700   1.000 42.77000  ? 652 HOH A O    1 
HETATM 5088 O  O    . HOH J 7 .   ? 34.71000  -14.65300 -41.12700 1.000 38.18000  ? 653 HOH A O    1 
HETATM 5089 O  O    . HOH J 7 .   ? 32.60800  -28.03900 -41.07300 1.000 26.10000  ? 654 HOH A O    1 
HETATM 5090 O  O    . HOH J 7 .   ? 10.61900  -9.65900  -45.64400 1.000 46.50000  ? 655 HOH A O    1 
HETATM 5091 O  O    . HOH J 7 .   ? 46.73500  -33.19300 -30.91400 1.000 52.15000  ? 656 HOH A O    1 
HETATM 5092 O  O    . HOH J 7 .   ? 12.66800  -20.22100 -37.44800 1.000 31.18000  ? 657 HOH A O    1 
HETATM 5093 O  O    . HOH J 7 .   ? 40.73000  -32.78500 -34.80600 1.000 31.17000  ? 658 HOH A O    1 
HETATM 5094 O  O    . HOH J 7 .   ? 44.94800  -41.26500 5.26800   1.000 51.52000  ? 659 HOH A O    1 
HETATM 5095 O  O    . HOH J 7 .   ? 23.67000  -32.87100 -19.08100 1.000 47.52000  ? 660 HOH A O    1 
HETATM 5096 O  O    . HOH J 7 .   ? 24.23800  -17.97000 -55.41300 1.000 36.12000  ? 661 HOH A O    1 
HETATM 5097 O  O    . HOH J 7 .   ? 38.93500  -28.09000 1.27900   1.000 40.80000  ? 662 HOH A O    1 
HETATM 5098 O  O    . HOH J 7 .   ? 11.40100  -19.40700 -51.34600 1.000 49.51000  ? 663 HOH A O    1 
HETATM 5099 O  O    . HOH J 7 .   ? -3.36100  -27.25500 -38.32100 1.000 46.07000  ? 664 HOH A O    1 
HETATM 5100 O  O    . HOH J 7 .   ? 38.79700  -31.80400 -41.45500 1.000 29.09000  ? 665 HOH A O    1 
HETATM 5101 O  O    . HOH J 7 .   ? 16.41300  -20.80300 -23.74700 1.000 39.02000  ? 666 HOH A O    1 
HETATM 5102 O  O    . HOH J 7 .   ? 28.34800  -14.73100 -26.98900 1.000 37.99000  ? 667 HOH A O    1 
HETATM 5103 O  O    . HOH J 7 .   ? 5.09100   -27.52300 -44.98200 1.000 51.34000  ? 668 HOH A O    1 
HETATM 5104 O  O    . HOH J 7 .   ? 34.44200  -27.87700 -48.84400 1.000 35.88000  ? 669 HOH A O    1 
HETATM 5105 O  O    . HOH J 7 .   ? 41.43900  -37.27000 -37.23900 1.000 46.82000  ? 670 HOH A O    1 
HETATM 5106 O  O    . HOH J 7 .   ? 18.77600  -19.35000 -50.50200 1.000 41.46000  ? 671 HOH A O    1 
HETATM 5107 O  O    . HOH J 7 .   ? 35.38200  -42.64800 -2.52100  1.000 52.21000  ? 672 HOH A O    1 
HETATM 5108 O  O    . HOH J 7 .   ? 18.90400  -35.34100 -27.05700 1.000 48.20000  ? 673 HOH A O    1 
HETATM 5109 O  O    . HOH J 7 .   ? 31.19200  -14.19400 -38.29100 1.000 39.84000  ? 674 HOH A O    1 
HETATM 5110 O  O    . HOH J 7 .   ? 44.56800  -22.16700 -38.25800 1.000 39.71000  ? 675 HOH A O    1 
HETATM 5111 O  O    . HOH J 7 .   ? 13.64100  -27.54200 -30.63400 1.000 44.01000  ? 676 HOH A O    1 
HETATM 5112 O  O    . HOH J 7 .   ? 38.81600  -40.17000 -35.55700 1.000 36.25000  ? 677 HOH A O    1 
HETATM 5113 O  O    . HOH J 7 .   ? -0.05900  -18.53300 -28.06700 1.000 45.40000  ? 678 HOH A O    1 
HETATM 5114 O  O    . HOH J 7 .   ? 27.28900  -36.10900 -8.62800  1.000 42.10000  ? 679 HOH A O    1 
HETATM 5115 O  O    . HOH J 7 .   ? 10.02100  -28.10800 -47.20400 1.000 46.17000  ? 680 HOH A O    1 
HETATM 5116 O  O    . HOH J 7 .   ? 39.61100  -24.91800 -24.39400 1.000 33.07000  ? 681 HOH A O    1 
HETATM 5117 O  O    . HOH J 7 .   ? 27.27500  -40.94700 -40.08200 1.000 40.44000  ? 682 HOH A O    1 
HETATM 5118 O  O    . HOH J 7 .   ? 37.50000  -14.40900 -27.78100 1.000 40.56000  ? 683 HOH A O    1 
HETATM 5119 O  O    . HOH J 7 .   ? 31.10000  -30.09000 -40.81500 1.000 40.44000  ? 684 HOH A O    1 
HETATM 5120 O  O    . HOH J 7 .   ? 19.734    -36.432   -13.392   1.000 27.05000  ? 685 HOH A O    1 
HETATM 5121 O  O    . HOH J 7 .   ? 37.20200  -17.16700 -21.10800 1.000 38.92000  ? 686 HOH A O    1 
HETATM 5122 O  O    . HOH J 7 .   ? 13.31900  -27.05800 -35.37900 1.000 31.23000  ? 687 HOH A O    1 
HETATM 5123 O  O    . HOH J 7 .   ? 29.22400  -43.68800 -33.78100 1.000 44.78000  ? 688 HOH A O    1 
HETATM 5124 O  O    . HOH J 7 .   ? 51.782    -25.848   0.971     1.000 50.26000  ? 689 HOH A O    1 
HETATM 5125 O  O    . HOH J 7 .   ? 15.24900  -14.88700 -46.95000 1.000 51.31000  ? 690 HOH A O    1 
HETATM 5126 O  O    . HOH J 7 .   ? 42.08300  -28.04200 -21.16600 1.000 51.39000  ? 691 HOH A O    1 
HETATM 5127 O  O    . HOH J 7 .   ? 36.39500  -32.82700 -42.68400 1.000 37.96000  ? 692 HOH A O    1 
HETATM 5128 O  O    . HOH J 7 .   ? 12.57000  -26.38600 -47.76800 1.000 32.77000  ? 693 HOH A O    1 
HETATM 5129 O  O    . HOH J 7 .   ? 17.15300  -12.57500 -26.06500 1.000 42.66000  ? 694 HOH A O    1 
HETATM 5130 O  O    . HOH J 7 .   ? 15.57800  -13.65600 -49.56600 1.000 52.44000  ? 695 HOH A O    1 
HETATM 5131 O  O    . HOH J 7 .   ? 15.96000  -25.03100 -54.07600 1.000 40.05000  ? 696 HOH A O    1 
HETATM 5132 O  O    . HOH J 7 .   ? 1.53700   -11.71800 -29.22100 1.000 53.23000  ? 697 HOH A O    1 
HETATM 5133 O  O    . HOH J 7 .   ? 3.93100   -25.53400 -48.39300 1.000 48.00000  ? 698 HOH A O    1 
HETATM 5134 O  O    . HOH J 7 .   ? 35.70300  -15.25300 -54.95300 1.000 53.40000  ? 699 HOH A O    1 
HETATM 5135 O  O    . HOH J 7 .   ? 42.19200  -28.13400 -14.41400 1.000 41.08000  ? 700 HOH A O    1 
HETATM 5136 O  O    . HOH J 7 .   ? 27.24600  -16.67600 -30.34200 1.000 40.73000  ? 701 HOH A O    1 
HETATM 5137 O  O    . HOH J 7 .   ? 36.74000  -30.22600 0.60800   1.000 46.49000  ? 702 HOH A O    1 
HETATM 5138 O  O    . HOH J 7 .   ? 4.14200   -10.13100 -45.96500 1.000 48.43000  ? 703 HOH A O    1 
HETATM 5139 O  O    . HOH J 7 .   ? 26.67100  -26.92200 -55.99400 1.000 43.28000  ? 704 HOH A O    1 
HETATM 5140 O  O    . HOH J 7 .   ? 19.18600  -7.91000  -34.86800 1.000 44.62000  ? 705 HOH A O    1 
HETATM 5141 O  O    . HOH J 7 .   ? 44.29100  -26.35800 -32.67700 1.000 37.16000  ? 706 HOH A O    1 
HETATM 5142 O  O    . HOH J 7 .   ? 8.70600   -5.53800  -41.10000 1.000 47.10000  ? 707 HOH A O    1 
HETATM 5143 O  O    . HOH J 7 .   ? 17.18000  -17.38600 -20.50500 1.000 38.42000  ? 708 HOH A O    1 
HETATM 5144 O  O    . HOH J 7 .   ? 28.41600  -11.50900 -43.33500 1.000 48.92000  ? 709 HOH A O    1 
HETATM 5145 O  O    . HOH J 7 .   ? 41.34400  -41.02700 -18.86200 1.000 36.44000  ? 710 HOH A O    1 
HETATM 5146 O  O    . HOH J 7 .   ? 28.24500  -31.60700 2.29700   1.000 42.20000  ? 711 HOH A O    1 
HETATM 5147 O  O    . HOH J 7 .   ? 26.56000  -43.15500 -32.74500 1.000 39.85000  ? 712 HOH A O    1 
HETATM 5148 O  O    . HOH J 7 .   ? 22.54600  -37.46400 -49.74100 1.000 42.18000  ? 713 HOH A O    1 
HETATM 5149 O  O    . HOH J 7 .   ? 15.97100  -34.09600 -52.85800 1.000 40.65000  ? 714 HOH A O    1 
HETATM 5150 O  O    . HOH J 7 .   ? 40.37200  -40.67800 -23.28000 1.000 42.64000  ? 715 HOH A O    1 
HETATM 5151 O  O    . HOH J 7 .   ? 45.75800  -29.26900 -13.34900 1.000 47.93000  ? 716 HOH A O    1 
HETATM 5152 O  O    . HOH J 7 .   ? 40.918    -27.258   -48.119   1.000 33.39000  ? 717 HOH A O    1 
HETATM 5153 O  O    . HOH J 7 .   ? 11.00900  -16.48700 -23.23100 1.000 42.93000  ? 718 HOH A O    1 
HETATM 5154 O  O    . HOH J 7 .   ? 7.55700   -30.63200 -39.86700 1.000 40.36000  ? 719 HOH A O    1 
HETATM 5155 O  O    . HOH J 7 .   ? 13.76000  -20.19900 -24.33800 1.000 38.73000  ? 720 HOH A O    1 
HETATM 5156 O  O    . HOH J 7 .   ? 34.04000  -32.47600 -40.80300 1.000 31.33000  ? 721 HOH A O    1 
HETATM 5157 O  O    . HOH J 7 .   ? 29.22000  -22.18200 -58.88200 1.000 44.26000  ? 722 HOH A O    1 
HETATM 5158 O  O    . HOH J 7 .   ? 5.26600   -23.86200 -35.14000 1.000 38.24000  ? 723 HOH A O    1 
HETATM 5159 O  O    . HOH J 7 .   ? 33.12800  -25.77700 -55.22600 1.000 44.95000  ? 724 HOH A O    1 
HETATM 5160 O  O    . HOH J 7 .   ? 41.50600  -25.76100 -27.10700 1.000 32.82000  ? 725 HOH A O    1 
HETATM 5161 O  O    . HOH J 7 .   ? 42.89700  -28.04800 -45.26000 1.000 40.72000  ? 726 HOH A O    1 
HETATM 5162 O  O    . HOH J 7 .   ? -5.05900  -28.73600 -36.64300 1.000 43.64000  ? 727 HOH A O    1 
HETATM 5163 O  O    . HOH J 7 .   ? 42.72600  -25.41800 -20.33400 1.000 53.93000  ? 728 HOH A O    1 
HETATM 5164 O  O    . HOH J 7 .   ? 20.52900  -45.30500 -32.76600 1.000 42.28000  ? 729 HOH A O    1 
HETATM 5165 O  O    . HOH J 7 .   ? 22.70000  -33.49500 -29.78300 1.000 34.83000  ? 730 HOH A O    1 
HETATM 5166 O  O    . HOH J 7 .   ? 20.25000  -13.63300 -43.86100 1.000 33.79000  ? 731 HOH A O    1 
HETATM 5167 O  O    . HOH J 7 .   ? 32.73000  -29.56200 -50.44800 1.000 43.84000  ? 732 HOH A O    1 
HETATM 5168 O  O    . HOH J 7 .   ? 46.95300  -27.53400 -12.07600 1.000 41.61000  ? 733 HOH A O    1 
HETATM 5169 O  O    . HOH J 7 .   ? 43.48100  -18.78300 -41.19400 1.000 41.59000  ? 734 HOH A O    1 
HETATM 5170 O  O    . HOH J 7 .   ? -4.147    -34.650   -46.791   1.000 47.09000  ? 735 HOH A O    1 
HETATM 5171 O  O    . HOH J 7 .   ? 29.36600  -22.89900 -2.76800  1.000 42.05000  ? 736 HOH A O    1 
HETATM 5172 O  O    . HOH J 7 .   ? 49.60700  -45.13600 -9.37200  1.000 51.26000  ? 737 HOH A O    1 
HETATM 5173 O  O    . HOH J 7 .   ? 42.38200  -32.19700 3.64600   1.000 47.98000  ? 738 HOH A O    1 
HETATM 5174 O  O    . HOH J 7 .   ? 35.40000  -42.43500 -32.85200 1.000 45.27000  ? 739 HOH A O    1 
HETATM 5175 O  O    . HOH J 7 .   ? 56.24700  -37.75200 -9.43500  1.000 52.87000  ? 740 HOH A O    1 
HETATM 5176 O  O    . HOH J 7 .   ? 32.39300  -17.19700 -42.74600 1.000 39.42000  ? 741 HOH A O    1 
HETATM 5177 O  O    . HOH J 7 .   ? 28.60400  -14.00300 -33.87100 1.000 40.40000  ? 742 HOH A O    1 
HETATM 5178 O  O    . HOH J 7 .   ? 31.82400  -21.44200 -59.00500 1.000 44.46000  ? 743 HOH A O    1 
HETATM 5179 O  O    . HOH J 7 .   ? 33.36600  -38.80500 -24.27000 1.000 22.54000  ? 744 HOH A O    1 
HETATM 5180 O  O    . HOH J 7 .   ? 8.49600   -26.35700 -35.72100 1.000 35.05000  ? 745 HOH A O    1 
HETATM 5181 O  O    . HOH J 7 .   ? 9.244     -31.189   -44.218   1.000 45.28000  ? 746 HOH A O    1 
HETATM 5182 O  O    . HOH J 7 .   ? 32.43300  -14.91600 -33.36600 1.000 42.94000  ? 747 HOH A O    1 
HETATM 5183 O  O    . HOH J 7 .   ? 29.09000  -25.75100 -55.62100 1.000 51.25000  ? 748 HOH A O    1 
HETATM 5184 O  O    . HOH J 7 .   ? 27.11800  -13.54300 -30.40900 1.000 41.73000  ? 749 HOH A O    1 
HETATM 5185 O  O    . HOH J 7 .   ? 22.45200  -19.55100 -11.23400 1.000 45.78000  ? 750 HOH A O    1 
HETATM 5186 O  O    . HOH J 7 .   ? 18.56600  -10.51600 -24.89300 1.000 52.74000  ? 751 HOH A O    1 
HETATM 5187 O  O    . HOH J 7 .   ? 14.86300  -9.54800  -30.30300 1.000 43.33000  ? 752 HOH A O    1 
HETATM 5188 O  O    . HOH J 7 .   ? 40.74300  -16.27400 -33.47900 1.000 49.66000  ? 753 HOH A O    1 
HETATM 5189 O  O    . HOH J 7 .   ? 35.843    -22.252   -57.519   1.000 47.39000  ? 754 HOH A O    1 
HETATM 5190 O  O    . HOH J 7 .   ? -8.25800  -25.79900 -48.05900 1.000 48.73000  ? 755 HOH A O    1 
HETATM 5191 O  O    . HOH J 7 .   ? 17.77500  -7.60500  -32.93900 1.000 49.14000  ? 756 HOH A O    1 
HETATM 5192 O  O    . HOH J 7 .   ? 24.63100  -12.75200 -42.99900 1.000 50.87000  ? 757 HOH A O    1 
HETATM 5193 O  O    . HOH J 7 .   ? 30.37700  -38.99700 -13.78800 1.000 41.40000  ? 758 HOH A O    1 
HETATM 5194 O  O    . HOH J 7 .   ? 44.01300  -40.94500 -19.86100 1.000 53.85000  ? 759 HOH A O    1 
HETATM 5195 O  O    . HOH J 7 .   ? 26.50000  -12.37600 -35.53200 1.000 50.32000  ? 760 HOH A O    1 
HETATM 5196 O  O    . HOH J 7 .   ? 34.97700  -42.98800 -20.50800 1.000 45.44000  ? 761 HOH A O    1 
HETATM 5197 O  O    . HOH J 7 .   ? 31.89300  -40.47800 -18.23400 1.000 39.47000  ? 762 HOH A O    1 
HETATM 5198 O  O    . HOH J 7 .   ? 34.07400  -41.46400 -24.19000 1.000 44.63000  ? 763 HOH A O    1 
HETATM 5199 O  O    . HOH J 7 .   ? 38.23700  -23.92500 -17.22900 1.000 46.68000  ? 764 HOH A O    1 
HETATM 5200 O  O    . HOH J 7 .   ? 32.44800  -42.22900 -21.93000 1.000 39.31000  ? 765 HOH A O    1 
HETATM 5201 O  O    . HOH J 7 .   ? 25.51800  -32.18300 -8.97800  1.000 43.20000  ? 766 HOH A O    1 
HETATM 5202 O  O    . HOH J 7 .   ? 35.92200  -42.50500 -28.05400 1.000 48.43000  ? 767 HOH A O    1 
HETATM 5203 O  O    . HOH J 7 .   ? 10.92600  -26.15800 -34.30400 1.000 34.75000  ? 768 HOH A O    1 
HETATM 5204 O  O    . HOH J 7 .   ? 35.676    -25.736   -56.034   1.000 44.83000  ? 769 HOH A O    1 
HETATM 5205 O  O    . HOH J 7 .   ? 23.694    -17.140   -6.015    1.000 48.03000  ? 770 HOH A O    1 
HETATM 5206 O  O    . HOH J 7 .   ? 28.64500  -9.93000  -51.02500 1.000 52.77000  ? 771 HOH A O    1 
HETATM 5207 O  O    . HOH J 7 .   ? 36.68900  -22.04000 -20.22700 1.000 38.23000  ? 772 HOH A O    1 
HETATM 5208 O  O    . HOH J 7 .   ? 36.90300  -40.91900 -18.77300 1.000 38.54000  ? 773 HOH A O    1 
HETATM 5209 O  O    . HOH J 7 .   ? 30.13400  -14.06800 -28.88800 1.000 46.54000  ? 774 HOH A O    1 
HETATM 5210 O  O    . HOH J 7 .   ? 34.33500  -26.92400 0.99300   1.000 46.66000  ? 775 HOH A O    1 
HETATM 5211 O  O    . HOH J 7 .   ? 19.49500  -22.33200 -14.68500 1.000 42.15000  ? 776 HOH A O    1 
HETATM 5212 O  O    . HOH J 7 .   ? 31.21300  -40.17600 -20.83600 1.000 34.45000  ? 777 HOH A O    1 
HETATM 5213 O  O    . HOH J 7 .   ? 35.84300  -43.81200 -7.17000  1.000 48.26000  ? 778 HOH A O    1 
HETATM 5214 O  O    . HOH J 7 .   ? 14.81600  -22.89300 -22.16300 1.000 49.12000  ? 779 HOH A O    1 
HETATM 5215 O  O    . HOH J 7 .   ? 26.94700  -39.19400 -22.61600 1.000 36.41000  ? 780 HOH A O    1 
HETATM 5216 O  O    . HOH J 7 .   ? 40.76500  -14.40900 -41.99900 1.000 47.17000  ? 781 HOH A O    1 
HETATM 5217 O  O    . HOH J 7 .   ? 32.40200  -14.00600 -22.09900 1.000 47.16000  ? 782 HOH A O    1 
HETATM 5218 O  O    . HOH J 7 .   ? 37.60200  -13.66000 -30.29400 1.000 47.03000  ? 783 HOH A O    1 
HETATM 5219 O  O    . HOH J 7 .   ? 42.44100  -36.66700 -32.08900 1.000 44.92000  ? 784 HOH A O    1 
HETATM 5220 O  O    . HOH J 7 .   ? 43.94600  -20.17900 -33.58300 1.000 47.50000  ? 785 HOH A O    1 
HETATM 5221 O  O    . HOH J 7 .   ? 37.52000  -45.63300 -6.18600  1.000 49.56000  ? 786 HOH A O    1 
HETATM 5222 O  O    . HOH J 7 .   ? 18.571    -39.325   -37.852   1.000 41.63000  ? 787 HOH A O    1 
HETATM 5223 O  O    . HOH J 7 .   ? 20.14400  -20.32500 -13.02200 1.000 47.46000  ? 788 HOH A O    1 
HETATM 5224 O  O    . HOH J 7 .   ? 30.51500  -20.17300 -7.39500  1.000 33.52000  ? 789 HOH A O    1 
HETATM 5225 O  O    . HOH J 7 .   ? 30.05500  -19.52400 -11.27400 1.000 34.21000  ? 790 HOH A O    1 
HETATM 5226 O  O    . HOH J 7 .   ? 35.83900  -15.00900 -20.46700 1.000 44.80000  ? 791 HOH A O    1 
HETATM 5227 O  O    . HOH J 7 .   ? 42.48800  -26.06500 -24.31000 1.000 42.66000  ? 792 HOH A O    1 
HETATM 5228 O  O    . HOH J 7 .   ? 24.61400  -44.20400 -34.30000 1.000 45.79000  ? 793 HOH A O    1 
HETATM 5229 O  O    . HOH J 7 .   ? 37.88700  -20.11100 -16.02400 1.000 45.63000  ? 794 HOH A O    1 
HETATM 5230 O  O    . HOH J 7 .   ? 42.55600  -35.00800 -34.42400 1.000 48.88000  ? 795 HOH A O    1 
HETATM 5231 O  O    . HOH J 7 .   ? 38.58400  -13.29100 -42.07300 1.000 48.66000  ? 796 HOH A O    1 
HETATM 5232 O  O    . HOH J 7 .   ? 21.31100  -47.37300 -34.28000 1.000 50.46000  ? 797 HOH A O    1 
HETATM 5233 O  O    . HOH J 7 .   ? 34.70100  -12.69800 -43.15800 1.000 47.61000  ? 798 HOH A O    1 
HETATM 5234 O  O    . HOH J 7 .   ? 6.907     -31.100   -43.474   1.000 46.01000  ? 799 HOH A O    1 
HETATM 5235 O  O    . HOH J 7 .   ? 30.27000  -40.46000 -16.22800 1.000 42.31000  ? 800 HOH A O    1 
HETATM 5236 O  O    . HOH J 7 .   ? 6.57300   -11.79100 -47.86200 1.000 48.52000  ? 801 HOH A O    1 
HETATM 5237 O  O    . HOH J 7 .   ? 18.07000  -12.44600 -28.52600 1.000 40.55000  ? 802 HOH A O    1 
HETATM 5238 O  O    . HOH J 7 .   ? 29.22400  -31.41200 -52.55400 1.000 47.33000  ? 803 HOH A O    1 
HETATM 5239 O  O    . HOH J 7 .   ? 27.26700  -11.48800 -32.62100 1.000 49.45000  ? 804 HOH A O    1 
HETATM 5240 O  O    . HOH J 7 .   ? 32.83500  -42.44000 -12.51300 1.000 49.01000  ? 805 HOH A O    1 
HETATM 5241 O  O    . HOH J 7 .   ? 37.92600  -20.02100 -18.96300 1.000 48.75000  ? 806 HOH A O    1 
HETATM 5242 O  O    . HOH J 7 .   ? 10.78000  -25.75500 -31.80800 1.000 42.80000  ? 807 HOH A O    1 
HETATM 5243 O  O    . HOH J 7 .   ? 41.17700  -33.09000 -41.99200 1.000 34.06000  ? 808 HOH A O    1 
HETATM 5244 O  O    . HOH J 7 .   ? -2.55300  -10.99500 -38.25600 1.000 53.39000  ? 809 HOH A O    1 
HETATM 5245 O  O    . HOH J 7 .   ? 13.41900  -26.46600 -52.74100 1.000 50.72000  ? 810 HOH A O    1 
HETATM 5246 O  O    . HOH J 7 .   ? 27.670    -16.863   -6.208    1.000 53.63000  ? 811 HOH A O    1 
HETATM 5247 O  O    . HOH J 7 .   ? -5.045    -27.025   -49.928   1.000 42.46000  ? 812 HOH A O    1 
HETATM 5248 O  O    . HOH J 7 .   ? 17.40700  -9.94300  -29.22100 1.000 46.12000  ? 813 HOH A O    1 
HETATM 5249 O  O    . HOH J 7 .   ? 36.91300  -34.45300 -48.50900 1.000 50.28000  ? 814 HOH A O    1 
HETATM 5250 O  O    . HOH J 7 .   ? 35.98000  -29.91300 -49.20300 1.000 39.98000  ? 815 HOH A O    1 
HETATM 5251 O  O    . HOH J 7 .   ? 34.95300  -28.40700 -55.17800 1.000 50.67000  ? 816 HOH A O    1 
HETATM 5252 O  O    . HOH J 7 .   ? 44.35800  -45.81900 -14.45200 1.000 46.94000  ? 817 HOH A O    1 
HETATM 5253 O  O    . HOH J 7 .   ? 43.61400  -26.63800 -28.35000 1.000 43.01000  ? 818 HOH A O    1 
HETATM 5254 O  O    . HOH J 7 .   ? 11.70583  -20.27510 -22.52883 0.50  49.92000  ? 819 HOH A O    1 
HETATM 5255 O  O    . HOH J 7 .   ? 40.48800  -18.19300 -13.14800 1.000 47.33000  ? 820 HOH A O    1 
HETATM 5256 O  O    . HOH J 7 .   ? -5.74100  -25.41600 -38.79900 1.000 46.12000  ? 821 HOH A O    1 
HETATM 5257 O  O    . HOH J 7 .   ? 25.69300  -16.40400 -12.90000 1.000 47.30000  ? 822 HOH A O    1 
HETATM 5258 O  O    . HOH J 7 .   ? 11.79200  -30.18100 -48.31400 1.000 45.57000  ? 823 HOH A O    1 
HETATM 5259 O  O    . HOH J 7 .   ? 43.83200  -28.86800 -38.85700 1.000 40.54000  ? 824 HOH A O    1 
HETATM 5260 O  O    . HOH J 7 .   ? 14.01100  -28.63500 -48.58900 1.000 34.06000  ? 825 HOH A O    1 
HETATM 5261 O  O    . HOH J 7 .   ? 35.14600  -44.76500 -9.52700  1.000 51.69000  ? 826 HOH A O    1 
HETATM 5262 O  O    . HOH J 7 .   ? 1.56200   -9.59800  -34.00800 1.000 50.86000  ? 827 HOH A O    1 
HETATM 5263 O  O    . HOH J 7 .   ? 26.959    -18.961   -4.631    1.000 46.80000  ? 828 HOH A O    1 
HETATM 5264 O  O    . HOH J 7 .   ? 23.757    -25.207   0.640     1.000 42.65000  ? 829 HOH A O    1 
HETATM 5265 O  O    . HOH J 7 .   ? 9.50400   -7.07300  -44.57000 1.000 52.48000  ? 830 HOH A O    1 
HETATM 5266 O  O    . HOH J 7 .   ? 2.28100   -27.03600 -50.57900 1.000 49.05000  ? 831 HOH A O    1 
HETATM 5267 O  O    . HOH J 7 .   ? 44.32600  -27.39400 -40.93900 1.000 36.00000  ? 832 HOH A O    1 
HETATM 5268 O  O    . HOH J 7 .   ? 27.36500  -44.65800 -30.67100 1.000 50.62000  ? 833 HOH A O    1 
HETATM 5269 O  O    . HOH J 7 .   ? -1.86200  -26.17200 -36.39300 1.000 41.67000  ? 834 HOH A O    1 
HETATM 5270 O  O    . HOH J 7 .   ? 31.85100  -17.92800 -12.55200 1.000 36.96000  ? 835 HOH A O    1 
HETATM 5271 O  O    . HOH J 7 .   ? 39.85200  -16.44500 -21.87700 1.000 47.59000  ? 836 HOH A O    1 
HETATM 5272 O  O    . HOH J 7 .   ? 28.31600  -41.00400 -20.88900 1.000 39.68000  ? 837 HOH A O    1 
HETATM 5273 O  O    . HOH J 7 .   ? 25.94600  -21.43800 -0.75300  1.000 47.90000  ? 838 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . VAL A 3   ? 0.70850 0.60940 0.65740 0.01300  -0.25700 0.10860  3   VAL A N   
2    C CA  . VAL A 3   ? 1.01340 0.91590 0.96260 0.00920  -0.23570 0.09890  3   VAL A CA  
3    C C   . VAL A 3   ? 0.91320 0.84200 0.88610 0.01070  -0.22630 0.08620  3   VAL A C   
4    O O   . VAL A 3   ? 0.90450 0.84550 0.87180 0.00370  -0.22790 0.08310  3   VAL A O   
5    C CB  . VAL A 3   ? 0.98010 0.86880 0.89230 -0.00530 -0.22630 0.10100  3   VAL A CB  
6    C CG1 . VAL A 3   ? 0.90070 0.78810 0.81540 -0.00770 -0.20640 0.09270  3   VAL A CG1 
7    C CG2 . VAL A 3   ? 1.05740 0.92100 0.94180 -0.00910 -0.23680 0.11540  3   VAL A CG2 
16   N N   . ARG A 4   ? 0.77960 0.71560 0.77730 0.01930  -0.21620 0.07870  4   ARG A N   
17   C CA  . ARG A 4   ? 0.65020 0.61060 0.67220 0.02200  -0.20700 0.06790  4   ARG A CA  
18   C C   . ARG A 4   ? 0.60960 0.56910 0.62120 0.01490  -0.18830 0.05980  4   ARG A C   
19   O O   . ARG A 4   ? 0.61620 0.56040 0.61840 0.01480  -0.18070 0.05990  4   ARG A O   
20   C CB  . ARG A 4   ? 0.60500 0.57520 0.66090 0.03700  -0.20790 0.06470  4   ARG A CB  
23   N N   . THR A 5   ? 0.59260 0.56800 0.60640 0.00880  -0.18200 0.05320  5   THR A N   
24   C CA  . THR A 5   ? 0.55150 0.52700 0.55620 0.00230  -0.16560 0.04570  5   THR A CA  
25   C C   . THR A 5   ? 0.53430 0.53110 0.56080 0.00410  -0.15760 0.03710  5   THR A C   
26   O O   . THR A 5   ? 0.53480 0.54770 0.57900 0.00620  -0.16480 0.03690  5   THR A O   
27   C CB  . THR A 5   ? 0.61570 0.58270 0.59040 -0.01070 -0.16430 0.04700  5   THR A CB  
28   O OG1 . THR A 5   ? 0.62500 0.60480 0.60120 -0.01520 -0.17160 0.04570  5   THR A OG1 
29   C CG2 . THR A 5   ? 0.61460 0.56090 0.56500 -0.01400 -0.17170 0.05680  5   THR A CG2 
37   N N   . ILE A 6   ? 0.52820 0.52490 0.55340 0.00270  -0.14280 0.03030  6   ILE A N   
38   C CA  . ILE A 6   ? 0.49310 0.50600 0.53020 0.00080  -0.13350 0.02290  6   ILE A CA  
39   C C   . ILE A 6   ? 0.52250 0.52820 0.53950 -0.00860 -0.12350 0.01900  6   ILE A C   
40   O O   . ILE A 6   ? 0.48120 0.47160 0.48020 -0.01160 -0.12050 0.02060  6   ILE A O   
41   C CB  . ILE A 6   ? 0.51510 0.53760 0.57430 0.01060  -0.12470 0.01790  6   ILE A CB  
42   C CG1 . ILE A 6   ? 0.49870 0.50590 0.54840 0.01380  -0.11730 0.01600  6   ILE A CG1 
43   C CG2 . ILE A 6   ? 0.54990 0.58360 0.63330 0.02050  -0.13300 0.02020  6   ILE A CG2 
44   C CD1 . ILE A 6   ? 0.51920 0.53380 0.58340 0.02140  -0.10670 0.00930  6   ILE A CD1 
56   N N   . LYS A 7   ? 0.48960 0.50680 0.51180 -0.01310 -0.11830 0.01400  7   LYS A N   
57   C CA  . LYS A 7   ? 0.45440 0.46700 0.46300 -0.02000 -0.10780 0.00890  7   LYS A CA  
58   C C   . LYS A 7   ? 0.43040 0.44620 0.44960 -0.01480 -0.09620 0.00410  7   LYS A C   
59   O O   . LYS A 7   ? 0.45360 0.48230 0.49190 -0.00950 -0.09410 0.00240  7   LYS A O   
60   C CB  . LYS A 7   ? 0.44450 0.46520 0.45230 -0.02770 -0.10890 0.00590  7   LYS A CB  
61   C CG  . LYS A 7   ? 0.52100 0.53570 0.51500 -0.03420 -0.09890 0.00040  7   LYS A CG  
62   C CD  . LYS A 7   ? 0.51650 0.53940 0.51470 -0.04050 -0.09940 -0.00360 7   LYS A CD  
63   C CE  . LYS A 7   ? 0.50770 0.54590 0.53120 -0.03660 -0.09660 -0.00460 7   LYS A CE  
64   N NZ  . LYS A 7   ? 0.51150 0.55710 0.54080 -0.04380 -0.09900 -0.00740 7   LYS A NZ  
78   N N   . VAL A 8   ? 0.43910 0.44390 0.44560 -0.01640 -0.08880 0.00200  8   VAL A N   
79   C CA  . VAL A 8   ? 0.39590 0.40230 0.40800 -0.01310 -0.07840 -0.00310 8   VAL A CA  
80   C C   . VAL A 8   ? 0.41340 0.41380 0.41160 -0.02030 -0.07170 -0.00650 8   VAL A C   
81   O O   . VAL A 8   ? 0.41720 0.41180 0.40140 -0.02710 -0.07400 -0.00530 8   VAL A O   
82   C CB  . VAL A 8   ? 0.42440 0.42310 0.43910 -0.00550 -0.07730 -0.00290 8   VAL A CB  
83   C CG1 . VAL A 8   ? 0.43090 0.43460 0.46000 0.00270  -0.08420 0.00000  8   VAL A CG1 
84   C CG2 . VAL A 8   ? 0.47300 0.45620 0.47180 -0.00960 -0.07840 -0.00050 8   VAL A CG2 
94   N N   . PHE A 9   ? 0.38970 0.39150 0.39150 -0.01830 -0.06340 -0.01100 9   PHE A N   
95   C CA  . PHE A 9   ? 0.40920 0.40570 0.40120 -0.02330 -0.05700 -0.01460 9   PHE A CA  
96   C C   . PHE A 9   ? 0.40130 0.39100 0.39240 -0.01960 -0.05290 -0.01630 9   PHE A C   
97   O O   . PHE A 9   ? 0.43330 0.42520 0.43270 -0.01280 -0.05170 -0.01750 9   PHE A O   
98   C CB  . PHE A 9   ? 0.39770 0.40120 0.39470 -0.02510 -0.05210 -0.01820 9   PHE A CB  
99   C CG  . PHE A 9   ? 0.38000 0.39020 0.38000 -0.02940 -0.05680 -0.01710 9   PHE A CG  
100  C CD1 . PHE A 9   ? 0.38300 0.38850 0.37080 -0.03650 -0.05970 -0.01780 9   PHE A CD1 
101  C CD2 . PHE A 9   ? 0.39850 0.42000 0.41350 -0.02660 -0.05830 -0.01580 9   PHE A CD2 
102  C CE1 . PHE A 9   ? 0.40990 0.42070 0.39990 -0.04080 -0.06550 -0.01740 9   PHE A CE1 
103  C CE2 . PHE A 9   ? 0.43500 0.46350 0.45510 -0.03130 -0.06360 -0.01480 9   PHE A CE2 
104  C CZ  . PHE A 9   ? 0.44690 0.46940 0.45410 -0.03850 -0.06810 -0.01580 9   PHE A CZ  
114  N N   . THR A 10  ? 0.39420 0.37620 0.37540 -0.02420 -0.05060 -0.01690 10  THR A N   
115  C CA  . THR A 10  ? 0.39260 0.36920 0.37440 -0.02230 -0.04670 -0.01940 10  THR A CA  
116  C C   . THR A 10  ? 0.38000 0.35890 0.36160 -0.02450 -0.04040 -0.02420 10  THR A C   
117  O O   . THR A 10  ? 0.36750 0.34920 0.34570 -0.02870 -0.03840 -0.02560 10  THR A O   
118  C CB  . THR A 10  ? 0.41900 0.38600 0.39350 -0.02590 -0.04820 -0.01630 10  THR A CB  
119  O OG1 . THR A 10  ? 0.41940 0.38540 0.38320 -0.03350 -0.04640 -0.01520 10  THR A OG1 
120  C CG2 . THR A 10  ? 0.43600 0.39800 0.41190 -0.02220 -0.05520 -0.01130 10  THR A CG2 
128  N N   . THR A 11  ? 0.38970 0.36660 0.37520 -0.02120 -0.03800 -0.02720 11  THR A N   
129  C CA  . THR A 11  ? 0.38030 0.35910 0.36750 -0.02150 -0.03340 -0.03140 11  THR A CA  
130  C C   . THR A 11  ? 0.35010 0.32490 0.34020 -0.01940 -0.03310 -0.03380 11  THR A C   
131  O O   . THR A 11  ? 0.35080 0.32130 0.34200 -0.01650 -0.03640 -0.03290 11  THR A O   
132  C CB  . THR A 11  ? 0.37110 0.35550 0.36230 -0.01770 -0.03230 -0.03230 11  THR A CB  
133  O OG1 . THR A 11  ? 0.37180 0.35650 0.36340 -0.01890 -0.02870 -0.03540 11  THR A OG1 
134  C CG2 . THR A 11  ? 0.37630 0.36040 0.37080 -0.01070 -0.03350 -0.03270 11  THR A CG2 
142  N N   . VAL A 12  ? 0.37300 0.34890 0.36520 -0.02070 -0.02990 -0.03720 12  VAL A N   
143  C CA  . VAL A 12  ? 0.37280 0.34680 0.36980 -0.01790 -0.03080 -0.04020 12  VAL A CA  
144  C C   . VAL A 12  ? 0.37230 0.34870 0.37090 -0.01360 -0.03030 -0.04270 12  VAL A C   
145  O O   . VAL A 12  ? 0.37290 0.34730 0.37340 -0.00990 -0.03280 -0.04510 12  VAL A O   
146  C CB  . VAL A 12  ? 0.37900 0.35250 0.38000 -0.02280 -0.02880 -0.04170 12  VAL A CB  
147  C CG1 . VAL A 12  ? 0.38740 0.35630 0.38560 -0.02730 -0.02980 -0.03800 12  VAL A CG1 
148  C CG2 . VAL A 12  ? 0.38080 0.35880 0.38250 -0.02620 -0.02350 -0.04360 12  VAL A CG2 
158  N N   . ASP A 13  ? 0.38370 0.36310 0.38080 -0.01410 -0.02780 -0.04210 13  ASP A N   
159  C CA  . ASP A 13  ? 0.40620 0.38610 0.40390 -0.01070 -0.02720 -0.04320 13  ASP A CA  
160  C C   . ASP A 13  ? 0.42490 0.40710 0.41990 -0.00890 -0.02620 -0.04040 13  ASP A C   
161  O O   . ASP A 13  ? 0.40970 0.39120 0.40350 -0.00660 -0.02530 -0.04010 13  ASP A O   
162  C CB  . ASP A 13  ? 0.39340 0.37380 0.39470 -0.01320 -0.02470 -0.04570 13  ASP A CB  
163  C CG  . ASP A 13  ? 0.41450 0.39590 0.41350 -0.01810 -0.02170 -0.04540 13  ASP A CG  
164  O OD1 . ASP A 13  ? 0.41070 0.39320 0.40610 -0.01950 -0.02230 -0.04260 13  ASP A OD1 
165  O OD2 . ASP A 13  ? 0.41790 0.39910 0.41920 -0.02050 -0.01880 -0.04850 13  ASP A OD2 
170  N N   . ASN A 14  ? 0.38910 0.37400 0.38360 -0.01000 -0.02650 -0.03800 14  ASN A N   
171  C CA  . ASN A 14  ? 0.41010 0.39980 0.40560 -0.00900 -0.02520 -0.03520 14  ASN A CA  
172  C C   . ASN A 14  ? 0.41270 0.40350 0.40930 -0.01330 -0.02320 -0.03440 14  ASN A C   
173  O O   . ASN A 14  ? 0.40770 0.40220 0.40630 -0.01330 -0.02150 -0.03190 14  ASN A O   
174  C CB  . ASN A 14  ? 0.44930 0.43930 0.44280 -0.00290 -0.02400 -0.03490 14  ASN A CB  
175  C CG  . ASN A 14  ? 0.47830 0.47520 0.47510 -0.00070 -0.02240 -0.03240 14  ASN A CG  
176  O OD1 . ASN A 14  ? 0.45620 0.45660 0.45750 -0.00200 -0.02430 -0.03110 14  ASN A OD1 
177  N ND2 . ASN A 14  ? 0.54620 0.54550 0.54100 0.00280  -0.01880 -0.03130 14  ASN A ND2 
184  N N   . ILE A 15  ? 0.40740 0.39500 0.40300 -0.01730 -0.02290 -0.03680 15  ILE A N   
185  C CA  . ILE A 15  ? 0.37740 0.36370 0.37340 -0.02130 -0.02150 -0.03740 15  ILE A CA  
186  C C   . ILE A 15  ? 0.41810 0.40450 0.41150 -0.02670 -0.02240 -0.03890 15  ILE A C   
187  O O   . ILE A 15  ? 0.42490 0.41340 0.41840 -0.03050 -0.02390 -0.03780 15  ILE A O   
188  C CB  . ILE A 15  ? 0.42380 0.40480 0.42050 -0.01980 -0.02010 -0.04020 15  ILE A CB  
189  C CG1 . ILE A 15  ? 0.41460 0.39430 0.41100 -0.01480 -0.02020 -0.03780 15  ILE A CG1 
190  C CG2 . ILE A 15  ? 0.45540 0.43270 0.45240 -0.02390 -0.01880 -0.04210 15  ILE A CG2 
191  C CD1 . ILE A 15  ? 0.46000 0.43470 0.45740 -0.01160 -0.02110 -0.04010 15  ILE A CD1 
203  N N   . ASN A 16  ? 0.42890 0.41300 0.41950 -0.02750 -0.02160 -0.04150 16  ASN A N   
204  C CA  . ASN A 16  ? 0.41470 0.39790 0.39910 -0.03270 -0.02170 -0.04270 16  ASN A CA  
205  C C   . ASN A 16  ? 0.39020 0.37550 0.37210 -0.03300 -0.02540 -0.03860 16  ASN A C   
206  O O   . ASN A 16  ? 0.37990 0.36450 0.36330 -0.03020 -0.02600 -0.03720 16  ASN A O   
207  C CB  . ASN A 16  ? 0.46940 0.45010 0.45290 -0.03360 -0.01760 -0.04690 16  ASN A CB  
208  C CG  . ASN A 16  ? 0.59240 0.57080 0.58070 -0.03170 -0.01490 -0.05100 16  ASN A CG  
209  O OD1 . ASN A 16  ? 0.56800 0.54350 0.55410 -0.03410 -0.01420 -0.05340 16  ASN A OD1 
210  N ND2 . ASN A 16  ? 0.51550 0.49420 0.51070 -0.02700 -0.01470 -0.05140 16  ASN A ND2 
217  N N   . LEU A 17  ? 0.40660 0.39350 0.38510 -0.03650 -0.02880 -0.03680 17  LEU A N   
218  C CA  . LEU A 17  ? 0.33250 0.32150 0.31030 -0.03600 -0.03390 -0.03220 17  LEU A CA  
219  C C   . LEU A 17  ? 0.38040 0.36530 0.34650 -0.04100 -0.03560 -0.03150 17  LEU A C   
220  O O   . LEU A 17  ? 0.42040 0.40270 0.37850 -0.04580 -0.03350 -0.03490 17  LEU A O   
221  C CB  . LEU A 17  ? 0.38310 0.37850 0.36740 -0.03580 -0.03780 -0.02990 17  LEU A CB  
222  C CG  . LEU A 17  ? 0.39150 0.39140 0.38570 -0.03180 -0.03470 -0.02990 17  LEU A CG  
223  C CD1 . LEU A 17  ? 0.43790 0.44640 0.44120 -0.03220 -0.03760 -0.02700 17  LEU A CD1 
224  C CD2 . LEU A 17  ? 0.42800 0.42690 0.42440 -0.02530 -0.03290 -0.02940 17  LEU A CD2 
236  N N   . HIS A 18  ? 0.37810 0.36140 0.34210 -0.03990 -0.03940 -0.02690 18  HIS A N   
237  C CA  . HIS A 18  ? 0.42270 0.40070 0.37350 -0.04480 -0.04150 -0.02430 18  HIS A CA  
238  C C   . HIS A 18  ? 0.43980 0.41880 0.39050 -0.04370 -0.05030 -0.01860 18  HIS A C   
239  O O   . HIS A 18  ? 0.39390 0.37320 0.35260 -0.03840 -0.05320 -0.01530 18  HIS A O   
240  C CB  . HIS A 18  ? 0.40910 0.38200 0.35760 -0.04520 -0.03730 -0.02360 18  HIS A CB  
241  C CG  . HIS A 18  ? 0.43450 0.40840 0.38620 -0.04580 -0.02930 -0.02930 18  HIS A CG  
242  N ND1 . HIS A 18  ? 0.46450 0.43720 0.40750 -0.05070 -0.02390 -0.03300 18  HIS A ND1 
243  C CD2 . HIS A 18  ? 0.41990 0.39600 0.38270 -0.04140 -0.02640 -0.03240 18  HIS A CD2 
244  C CE1 . HIS A 18  ? 0.44810 0.42290 0.39930 -0.04900 -0.01790 -0.03800 18  HIS A CE1 
245  N NE2 . HIS A 18  ? 0.40970 0.38630 0.37240 -0.04350 -0.02000 -0.03730 18  HIS A NE2 
254  N N   . THR A 19  ? 0.41500 0.39430 0.35700 -0.04830 -0.05520 -0.01780 19  THR A N   
255  C CA  . THR A 19  ? 0.44740 0.42890 0.39090 -0.04710 -0.06540 -0.01240 19  THR A CA  
256  C C   . THR A 19  ? 0.47370 0.44720 0.40920 -0.04660 -0.06900 -0.00600 19  THR A C   
257  O O   . THR A 19  ? 0.46210 0.42760 0.38210 -0.05150 -0.06560 -0.00510 19  THR A O   
258  C CB  . THR A 19  ? 0.42450 0.40690 0.35850 -0.05310 -0.07110 -0.01340 19  THR A CB  
259  O OG1 . THR A 19  ? 0.42630 0.41290 0.36560 -0.05510 -0.06690 -0.01980 19  THR A OG1 
260  C CG2 . THR A 19  ? 0.41910 0.40730 0.36090 -0.05100 -0.08260 -0.00840 19  THR A CG2 
268  N N   . GLN A 20  ? 0.41500 0.39020 0.36120 -0.04050 -0.07540 -0.00150 20  GLN A N   
269  C CA  . GLN A 20  ? 0.46080 0.42660 0.40070 -0.03940 -0.08060 0.00530  20  GLN A CA  
270  C C   . GLN A 20  ? 0.51190 0.48080 0.45710 -0.03590 -0.09270 0.01070  20  GLN A C   
271  O O   . GLN A 20  ? 0.52000 0.50000 0.48260 -0.03080 -0.09510 0.00890  20  GLN A O   
272  C CB  . GLN A 20  ? 0.47440 0.43620 0.42400 -0.03360 -0.07690 0.00520  20  GLN A CB  
273  C CG  . GLN A 20  ? 0.49750 0.45770 0.44620 -0.03580 -0.06650 0.00000  20  GLN A CG  
274  C CD  . GLN A 20  ? 0.51740 0.47040 0.44960 -0.04400 -0.06220 0.00130  20  GLN A CD  
275  O OE1 . GLN A 20  ? 0.50280 0.44800 0.42190 -0.04780 -0.06660 0.00770  20  GLN A OE1 
276  N NE2 . GLN A 20  ? 0.54050 0.49610 0.47310 -0.04660 -0.05310 -0.00460 20  GLN A NE2 
285  N N   . VAL A 21  ? 0.48290 0.44230 0.41370 -0.03870 -0.10020 0.01770  21  VAL A N   
286  C CA  . VAL A 21  ? 0.49730 0.45760 0.43390 -0.03420 -0.11340 0.02410  21  VAL A CA  
287  C C   . VAL A 21  ? 0.55260 0.50140 0.49100 -0.02910 -0.11560 0.02980  21  VAL A C   
288  O O   . VAL A 21  ? 0.59410 0.52910 0.51500 -0.03410 -0.11490 0.03480  21  VAL A O   
289  C CB  . VAL A 21  ? 0.61280 0.56930 0.53020 -0.04080 -0.12280 0.02860  21  VAL A CB  
290  C CG1 . VAL A 21  ? 0.62370 0.58130 0.54920 -0.03520 -0.13810 0.03590  21  VAL A CG1 
291  C CG2 . VAL A 21  ? 0.61160 0.57760 0.52690 -0.04630 -0.12050 0.02160  21  VAL A CG2 
301  N N   . VAL A 22  ? 0.54420 0.49800 0.50370 -0.01940 -0.11750 0.02870  22  VAL A N   
302  C CA  . VAL A 22  ? 0.54040 0.48220 0.50370 -0.01370 -0.11880 0.03210  22  VAL A CA  
303  C C   . VAL A 22  ? 0.58380 0.52220 0.55350 -0.00710 -0.13250 0.03940  22  VAL A C   
304  O O   . VAL A 22  ? 0.57390 0.52530 0.55710 -0.00280 -0.13930 0.03910  22  VAL A O   
305  C CB  . VAL A 22  ? 0.56200 0.50870 0.54230 -0.00650 -0.11040 0.02450  22  VAL A CB  
306  C CG1 . VAL A 22  ? 0.57780 0.52360 0.55010 -0.01280 -0.09860 0.01900  22  VAL A CG1 
307  C CG2 . VAL A 22  ? 0.58730 0.55200 0.58770 0.00030  -0.11050 0.01990  22  VAL A CG2 
317  N N   . ASP A 23  ? 0.59870 0.51930 0.56000 -0.00650 -0.13690 0.04620  23  ASP A N   
318  C CA  . ASP A 23  ? 0.60960 0.52250 0.57590 0.00030  -0.15070 0.05430  23  ASP A CA  
319  C C   . ASP A 23  ? 0.61060 0.52680 0.60160 0.01310  -0.15010 0.04930  23  ASP A C   
320  O O   . ASP A 23  ? 0.57580 0.48440 0.56890 0.01480  -0.14220 0.04490  23  ASP A O   
321  C CB  . ASP A 23  ? 0.60200 0.49200 0.54690 -0.00560 -0.15420 0.06390  23  ASP A CB  
322  C CG  . ASP A 23  ? 0.67790 0.55600 0.62460 0.00080  -0.16970 0.07400  23  ASP A CG  
323  O OD1 . ASP A 23  ? 0.62900 0.51370 0.59860 0.01280  -0.17630 0.07210  23  ASP A OD1 
324  O OD2 . ASP A 23  ? 0.75410 0.61560 0.67840 -0.00620 -0.17500 0.08420  23  ASP A OD2 
329  N N   . MET A 24  ? 0.57720 0.50530 0.58730 0.02210  -0.15820 0.04940  24  MET A N   
330  C CA  . MET A 24  ? 0.59470 0.52880 0.62920 0.03490  -0.15590 0.04330  24  MET A CA  
331  C C   . MET A 24  ? 0.62760 0.54140 0.66400 0.04260  -0.16250 0.04750  24  MET A C   
332  O O   . MET A 24  ? 0.60070 0.51640 0.65550 0.05400  -0.16010 0.04140  24  MET A O   
333  C CB  . MET A 24  ? 0.55140 0.50730 0.60890 0.04210  -0.16120 0.04170  24  MET A CB  
334  C CG  . MET A 24  ? 0.59720 0.57220 0.65530 0.03460  -0.15410 0.03670  24  MET A CG  
335  S SD  . MET A 24  ? 0.70640 0.70750 0.79280 0.04060  -0.16150 0.03620  24  MET A SD  
336  C CE  . MET A 24  ? 0.63150 0.64420 0.74330 0.05310  -0.14900 0.02670  24  MET A CE  
346  N N   . SER A 25  ? 0.58060 0.47450 0.59780 0.03650  -0.17020 0.05760  25  SER A N   
347  C CA  . SER A 25  ? 0.63390 0.50500 0.65090 0.04220  -0.17690 0.06270  25  SER A CA  
348  C C   . SER A 25  ? 0.63940 0.49420 0.64480 0.03610  -0.16730 0.06000  25  SER A C   
349  O O   . SER A 25  ? 0.64900 0.48360 0.65540 0.04020  -0.17160 0.06280  25  SER A O   
350  C CB  . SER A 25  ? 0.62890 0.48540 0.63140 0.03880  -0.19170 0.07680  25  SER A CB  
351  O OG  . SER A 25  ? 0.72020 0.56530 0.69440 0.02410  -0.18800 0.08300  25  SER A OG  
357  N N   . MET A 26  ? 0.65510 0.51810 0.65120 0.02660  -0.15520 0.05460  26  MET A N   
358  C CA  . MET A 26  ? 0.60490 0.45580 0.59220 0.02000  -0.14610 0.05150  26  MET A CA  
359  C C   . MET A 26  ? 0.59170 0.45660 0.59160 0.02440  -0.13510 0.03830  26  MET A C   
360  O O   . MET A 26  ? 0.59330 0.47850 0.60160 0.02700  -0.13120 0.03290  26  MET A O   
361  C CB  . MET A 26  ? 0.67810 0.52630 0.64310 0.00500  -0.14130 0.05680  26  MET A CB  
362  C CG  . MET A 26  ? 0.66780 0.50010 0.61500 -0.00090 -0.15110 0.07080  26  MET A CG  
363  S SD  . MET A 26  ? 0.82410 0.65910 0.74440 -0.01760 -0.14350 0.07520  26  MET A SD  
364  C CE  . MET A 26  ? 1.01990 0.83700 0.93270 -0.02670 -0.13480 0.07720  26  MET A CE  
374  N N   . THR A 27  ? 0.59480 0.44800 0.59570 0.02490  -0.13050 0.03330  27  THR A N   
375  C CA  . THR A 27  ? 0.57230 0.43710 0.58100 0.02800  -0.12050 0.02120  27  THR A CA  
376  C C   . THR A 27  ? 0.54690 0.42310 0.54560 0.01700  -0.11130 0.01940  27  THR A C   
377  O O   . THR A 27  ? 0.53340 0.40580 0.51850 0.00650  -0.11130 0.02620  27  THR A O   
378  C CB  . THR A 27  ? 0.58810 0.43640 0.59960 0.03140  -0.11960 0.01570  27  THR A CB  
379  O OG1 . THR A 27  ? 0.60040 0.43650 0.59970 0.01920  -0.11730 0.01930  27  THR A OG1 
380  C CG2 . THR A 27  ? 0.61440 0.44710 0.63420 0.04160  -0.12940 0.01810  27  THR A CG2 
388  N N   . TYR A 28  ? 0.50200 0.39250 0.50740 0.02000  -0.10320 0.01000  28  TYR A N   
389  C CA  . TYR A 28  ? 0.50300 0.40260 0.50070 0.01090  -0.09480 0.00740  28  TYR A CA  
390  C C   . TYR A 28  ? 0.51990 0.40630 0.50850 0.00200  -0.09230 0.00880  28  TYR A C   
391  O O   . TYR A 28  ? 0.51860 0.40780 0.49760 -0.00790 -0.08810 0.01160  28  TYR A O   
392  C CB  . TYR A 28  ? 0.48700 0.40030 0.49290 0.01630  -0.08740 -0.00240 28  TYR A CB  
393  C CG  . TYR A 28  ? 0.47420 0.40480 0.48830 0.02080  -0.08710 -0.00280 28  TYR A CG  
394  C CD1 . TYR A 28  ? 0.45000 0.39080 0.45920 0.01360  -0.08600 0.00030  28  TYR A CD1 
395  C CD2 . TYR A 28  ? 0.46570 0.40260 0.49330 0.03210  -0.08770 -0.00660 28  TYR A CD2 
396  C CE1 . TYR A 28  ? 0.50660 0.46320 0.52490 0.01650  -0.08650 0.00000  28  TYR A CE1 
397  C CE2 . TYR A 28  ? 0.47260 0.42710 0.51060 0.03540  -0.08700 -0.00660 28  TYR A CE2 
398  C CZ  . TYR A 28  ? 0.48640 0.45060 0.52010 0.02700  -0.08690 -0.00300 28  TYR A CZ  
399  O OH  . TYR A 28  ? 0.47220 0.45380 0.51750 0.02890  -0.08700 -0.00280 28  TYR A OH  
409  N N   . GLY A 29  ? 0.54310 0.41510 0.53540 0.00530  -0.09480 0.00650  29  GLY A N   
410  C CA  . GLY A 29  ? 0.54930 0.40990 0.53630 -0.00380 -0.09260 0.00750  29  GLY A CA  
411  C C   . GLY A 29  ? 0.55870 0.41020 0.53440 -0.01390 -0.09480 0.01880  29  GLY A C   
412  O O   . GLY A 29  ? 0.58410 0.43630 0.55360 -0.02440 -0.08890 0.02040  29  GLY A O   
416  N N   . GLN A 30  ? 0.60750 0.45040 0.58030 -0.01070 -0.10310 0.02680  30  GLN A N   
417  C CA  . GLN A 30  ? 0.61100 0.44380 0.56960 -0.02020 -0.10580 0.03860  30  GLN A CA  
418  C C   . GLN A 30  ? 0.63450 0.48140 0.58160 -0.02820 -0.09970 0.04040  30  GLN A C   
419  O O   . GLN A 30  ? 0.63280 0.47310 0.56520 -0.03830 -0.09820 0.04850  30  GLN A O   
420  C CB  . GLN A 30  ? 0.64740 0.46940 0.60490 -0.01390 -0.11760 0.04710  30  GLN A CB  
421  C CG  . GLN A 30  ? 0.76860 0.57460 0.73760 -0.00450 -0.12460 0.04530  30  GLN A CG  
422  C CD  . GLN A 30  ? 0.77310 0.57000 0.74330 0.00330  -0.13690 0.05350  30  GLN A CD  
423  O OE1 . GLN A 30  ? 0.76060 0.56440 0.74470 0.01590  -0.14110 0.04850  30  GLN A OE1 
424  N NE2 . GLN A 30  ? 0.90630 0.68770 0.86240 -0.00410 -0.14280 0.06650  30  GLN A NE2 
433  N N   . GLN A 31  ? 0.60850 0.47360 0.56100 -0.02400 -0.09600 0.03290  31  GLN A N   
434  C CA  . GLN A 31  ? 0.57680 0.45420 0.51910 -0.03010 -0.09180 0.03360  31  GLN A CA  
435  C C   . GLN A 31  ? 0.58000 0.46870 0.52400 -0.03480 -0.08060 0.02550  31  GLN A C   
436  O O   . GLN A 31  ? 0.56830 0.46050 0.50090 -0.04330 -0.07490 0.02700  31  GLN A O   
437  C CB  . GLN A 31  ? 0.52470 0.41410 0.47260 -0.02270 -0.09730 0.03230  31  GLN A CB  
438  C CG  . GLN A 31  ? 0.58330 0.46360 0.53280 -0.01660 -0.10950 0.03990  31  GLN A CG  
439  C CD  . GLN A 31  ? 0.61400 0.50770 0.57120 -0.01020 -0.11580 0.03940  31  GLN A CD  
440  O OE1 . GLN A 31  ? 0.63400 0.53610 0.58220 -0.01540 -0.11650 0.04090  31  GLN A OE1 
441  N NE2 . GLN A 31  ? 0.56470 0.46200 0.54010 0.00140  -0.11970 0.03600  31  GLN A NE2 
450  N N   . PHE A 32  ? 0.56580 0.45940 0.52320 -0.02890 -0.07750 0.01700  32  PHE A N   
451  C CA  . PHE A 32  ? 0.52530 0.42970 0.48610 -0.03160 -0.06860 0.00930  32  PHE A CA  
452  C C   . PHE A 32  ? 0.55710 0.45580 0.52460 -0.03340 -0.06550 0.00540  32  PHE A C   
453  O O   . PHE A 32  ? 0.53940 0.44640 0.51020 -0.03620 -0.05880 -0.00020 32  PHE A O   
454  C CB  . PHE A 32  ? 0.50200 0.41940 0.47200 -0.02350 -0.06750 0.00200  32  PHE A CB  
455  C CG  . PHE A 32  ? 0.51120 0.43760 0.47900 -0.02190 -0.07010 0.00400  32  PHE A CG  
456  C CD1 . PHE A 32  ? 0.54500 0.47160 0.50030 -0.02900 -0.07080 0.00900  32  PHE A CD1 
457  C CD2 . PHE A 32  ? 0.57370 0.50910 0.55210 -0.01340 -0.07170 0.00020  32  PHE A CD2 
458  C CE1 . PHE A 32  ? 0.53590 0.47090 0.49020 -0.02780 -0.07460 0.01000  32  PHE A CE1 
459  C CE2 . PHE A 32  ? 0.57320 0.51830 0.55280 -0.01250 -0.07440 0.00180  32  PHE A CE2 
460  C CZ  . PHE A 32  ? 0.57810 0.52280 0.54610 -0.01980 -0.07670 0.00650  32  PHE A CZ  
470  N N   . GLY A 33  ? 0.49870 0.38330 0.46940 -0.03160 -0.07100 0.00770  33  GLY A N   
471  C CA  . GLY A 33  ? 0.54880 0.42860 0.52840 -0.03080 -0.07040 0.00170  33  GLY A CA  
472  C C   . GLY A 33  ? 0.51770 0.40310 0.50500 -0.01980 -0.07180 -0.00700 33  GLY A C   
473  O O   . GLY A 33  ? 0.51950 0.41040 0.50730 -0.01250 -0.07380 -0.00700 33  GLY A O   
477  N N   . PRO A 34  ? 0.48530 0.36990 0.47860 -0.01860 -0.07080 -0.01430 34  PRO A N   
478  C CA  . PRO A 34  ? 0.47020 0.35890 0.46750 -0.00820 -0.07150 -0.02260 34  PRO A CA  
479  C C   . PRO A 34  ? 0.44050 0.34550 0.43660 -0.00490 -0.06680 -0.02390 34  PRO A C   
480  O O   . PRO A 34  ? 0.47290 0.38750 0.46710 -0.01060 -0.06170 -0.02350 34  PRO A O   
481  C CB  . PRO A 34  ? 0.49030 0.37740 0.49140 -0.01050 -0.07090 -0.02950 34  PRO A CB  
482  C CG  . PRO A 34  ? 0.52650 0.40270 0.52940 -0.02030 -0.07260 -0.02450 34  PRO A CG  
483  C CD  . PRO A 34  ? 0.49620 0.37620 0.49300 -0.02680 -0.06920 -0.01530 34  PRO A CD  
491  N N   . THR A 35  ? 0.44620 0.35420 0.44460 0.00440  -0.06840 -0.02570 35  THR A N   
492  C CA  . THR A 35  ? 0.42660 0.34940 0.42570 0.00720  -0.06470 -0.02560 35  THR A CA  
493  C C   . THR A 35  ? 0.43110 0.35880 0.43390 0.01710  -0.06290 -0.03220 35  THR A C   
494  O O   . THR A 35  ? 0.43460 0.35420 0.44000 0.02440  -0.06610 -0.03510 35  THR A O   
495  C CB  . THR A 35  ? 0.47110 0.39550 0.47050 0.00730  -0.06840 -0.01850 35  THR A CB  
496  O OG1 . THR A 35  ? 0.46660 0.38460 0.45910 -0.00190 -0.06990 -0.01200 35  THR A OG1 
497  C CG2 . THR A 35  ? 0.45420 0.39440 0.45590 0.00820  -0.06520 -0.01840 35  THR A CG2 
505  N N   . TYR A 36  ? 0.43840 0.37840 0.44070 0.01730  -0.05730 -0.03460 36  TYR A N   
506  C CA  . TYR A 36  ? 0.41980 0.36490 0.42280 0.02530  -0.05390 -0.04030 36  TYR A CA  
507  C C   . TYR A 36  ? 0.46220 0.42240 0.46890 0.02620  -0.04920 -0.03820 36  TYR A C   
508  O O   . TYR A 36  ? 0.42440 0.39090 0.43050 0.01940  -0.04780 -0.03450 36  TYR A O   
509  C CB  . TYR A 36  ? 0.41190 0.35460 0.40900 0.02420  -0.05200 -0.04580 36  TYR A CB  
510  C CG  . TYR A 36  ? 0.41900 0.34810 0.41460 0.02180  -0.05700 -0.04840 36  TYR A CG  
511  C CD1 . TYR A 36  ? 0.44180 0.36800 0.43830 0.01270  -0.05840 -0.04490 36  TYR A CD1 
512  C CD2 . TYR A 36  ? 0.42830 0.34760 0.42170 0.02850  -0.06000 -0.05470 36  TYR A CD2 
513  C CE1 . TYR A 36  ? 0.45910 0.37380 0.45660 0.00950  -0.06280 -0.04690 36  TYR A CE1 
514  C CE2 . TYR A 36  ? 0.46790 0.37420 0.46090 0.02560  -0.06550 -0.05730 36  TYR A CE2 
515  C CZ  . TYR A 36  ? 0.47820 0.38260 0.47430 0.01570  -0.06690 -0.05310 36  TYR A CZ  
516  O OH  . TYR A 36  ? 0.54080 0.43280 0.53870 0.01220  -0.07230 -0.05570 36  TYR A OH  
526  N N   . LEU A 37  ? 0.42650 0.39240 0.43760 0.03460  -0.04660 -0.04080 37  LEU A N   
527  C CA  . LEU A 37  ? 0.44070 0.42200 0.45790 0.03590  -0.04150 -0.03900 37  LEU A CA  
528  C C   . LEU A 37  ? 0.48490 0.46950 0.49670 0.04020  -0.03470 -0.04390 37  LEU A C   
529  O O   . LEU A 37  ? 0.47310 0.45640 0.48480 0.04870  -0.03260 -0.04860 37  LEU A O   
530  C CB  . LEU A 37  ? 0.45890 0.44580 0.48800 0.04200  -0.04370 -0.03710 37  LEU A CB  
531  C CG  . LEU A 37  ? 0.50610 0.51090 0.54580 0.04320  -0.03880 -0.03500 37  LEU A CG  
532  C CD1 . LEU A 37  ? 0.44210 0.45260 0.48000 0.03300  -0.03870 -0.03060 37  LEU A CD1 
533  C CD2 . LEU A 37  ? 0.49300 0.50400 0.54750 0.04920  -0.04280 -0.03290 37  LEU A CD2 
545  N N   . ASP A 38  ? 0.49900 0.48670 0.50500 0.03460  -0.03140 -0.04300 38  ASP A N   
546  C CA  . ASP A 38  ? 0.47310 0.46190 0.47060 0.03760  -0.02590 -0.04630 38  ASP A CA  
547  C C   . ASP A 38  ? 0.51180 0.48930 0.50070 0.04390  -0.02800 -0.05300 38  ASP A C   
548  O O   . ASP A 38  ? 0.48280 0.46160 0.46670 0.05110  -0.02340 -0.05710 38  ASP A O   
549  C CB  . ASP A 38  ? 0.53690 0.53920 0.53980 0.04090  -0.01830 -0.04470 38  ASP A CB  
550  C CG  . ASP A 38  ? 0.67350 0.67680 0.66520 0.04210  -0.01190 -0.04600 38  ASP A CG  
551  O OD1 . ASP A 38  ? 0.61300 0.61050 0.59630 0.03730  -0.01380 -0.04530 38  ASP A OD1 
552  O OD2 . ASP A 38  ? 0.69870 0.70850 0.68960 0.04800  -0.00500 -0.04760 38  ASP A OD2 
557  N N   . GLY A 39  ? 0.44920 0.41530 0.43600 0.04080  -0.03470 -0.05440 39  GLY A N   
558  C CA  . GLY A 39  ? 0.47730 0.43100 0.45640 0.04500  -0.03860 -0.06110 39  GLY A CA  
559  C C   . GLY A 39  ? 0.45590 0.40120 0.43960 0.05050  -0.04240 -0.06390 39  GLY A C   
560  O O   . GLY A 39  ? 0.50000 0.43190 0.47980 0.05100  -0.04810 -0.06850 39  GLY A O   
564  N N   . ALA A 40  ? 0.45660 0.40900 0.44980 0.05450  -0.04030 -0.06130 40  ALA A N   
565  C CA  . ALA A 40  ? 0.43610 0.38000 0.43500 0.06100  -0.04440 -0.06360 40  ALA A CA  
566  C C   . ALA A 40  ? 0.46180 0.39670 0.46510 0.05420  -0.05210 -0.05820 40  ALA A C   
567  O O   . ALA A 40  ? 0.46210 0.40400 0.46900 0.04700  -0.05230 -0.05120 40  ALA A O   
568  C CB  . ALA A 40  ? 0.47110 0.42750 0.48100 0.06820  -0.03980 -0.06240 40  ALA A CB  
574  N N   . ASP A 41  ? 0.48140 0.39990 0.48340 0.05620  -0.05830 -0.06160 41  ASP A N   
575  C CA  . ASP A 41  ? 0.44670 0.35430 0.45130 0.04910  -0.06520 -0.05600 41  ASP A CA  
576  C C   . ASP A 41  ? 0.46420 0.37210 0.47780 0.05300  -0.06830 -0.05050 41  ASP A C   
577  O O   . ASP A 41  ? 0.51710 0.41780 0.53520 0.06230  -0.07080 -0.05420 41  ASP A O   
578  C CB  . ASP A 41  ? 0.52130 0.41050 0.52160 0.04920  -0.07080 -0.06170 41  ASP A CB  
579  C CG  . ASP A 41  ? 0.54790 0.42490 0.55070 0.04060  -0.07710 -0.05550 41  ASP A CG  
580  O OD1 . ASP A 41  ? 0.52350 0.40450 0.52960 0.03630  -0.07760 -0.04670 41  ASP A OD1 
581  O OD2 . ASP A 41  ? 0.55640 0.41930 0.55710 0.03780  -0.08160 -0.05930 41  ASP A OD2 
586  N N   . VAL A 42  ? 0.49920 0.41500 0.51550 0.04620  -0.06890 -0.04210 42  VAL A N   
587  C CA  . VAL A 42  ? 0.50150 0.41840 0.52570 0.04900  -0.07360 -0.03570 42  VAL A CA  
588  C C   . VAL A 42  ? 0.50780 0.41040 0.52820 0.04140  -0.08080 -0.02820 42  VAL A C   
589  O O   . VAL A 42  ? 0.48290 0.38630 0.50620 0.04060  -0.08560 -0.02070 42  VAL A O   
590  C CB  . VAL A 42  ? 0.46510 0.40150 0.49450 0.04730  -0.07020 -0.03150 42  VAL A CB  
591  C CG1 . VAL A 42  ? 0.51160 0.46190 0.54670 0.05520  -0.06270 -0.03760 42  VAL A CG1 
592  C CG2 . VAL A 42  ? 0.47880 0.41980 0.50030 0.03550  -0.06790 -0.02760 42  VAL A CG2 
602  N N   . THR A 43  ? 0.51590 0.40560 0.52980 0.03550  -0.08180 -0.02980 43  THR A N   
603  C CA  . THR A 43  ? 0.51350 0.39020 0.52320 0.02670  -0.08680 -0.02200 43  THR A CA  
604  C C   . THR A 43  ? 0.54340 0.40750 0.55700 0.03200  -0.09500 -0.01670 43  THR A C   
605  O O   . THR A 43  ? 0.53560 0.39540 0.54550 0.02630  -0.09920 -0.00700 43  THR A O   
606  C CB  . THR A 43  ? 0.51890 0.38380 0.52510 0.02090  -0.08690 -0.02590 43  THR A CB  
607  O OG1 . THR A 43  ? 0.50750 0.38480 0.51120 0.01650  -0.08030 -0.03010 43  THR A OG1 
608  C CG2 . THR A 43  ? 0.53500 0.38740 0.53750 0.01050  -0.09040 -0.01710 43  THR A CG2 
616  N N   . LYS A 44  ? 0.53390 0.39120 0.55410 0.04340  -0.09740 -0.02310 44  LYS A N   
617  C CA  . LYS A 44  ? 0.58970 0.43160 0.61520 0.05000  -0.10600 -0.01940 44  LYS A CA  
618  C C   . LYS A 44  ? 0.59410 0.44830 0.62970 0.05930  -0.10810 -0.01680 44  LYS A C   
619  O O   . LYS A 44  ? 0.59610 0.43950 0.63890 0.06730  -0.11560 -0.01430 44  LYS A O   
620  C CB  . LYS A 44  ? 0.64340 0.46960 0.67150 0.05810  -0.10780 -0.02920 44  LYS A CB  
621  C CG  . LYS A 44  ? 0.73160 0.53910 0.75300 0.04890  -0.11050 -0.02950 44  LYS A CG  
622  C CD  . LYS A 44  ? 0.95870 0.74690 0.98290 0.05760  -0.11490 -0.03900 44  LYS A CD  
623  C CE  . LYS A 44  ? 1.24260 1.01980 1.26120 0.04940  -0.11520 -0.04470 44  LYS A CE  
624  N NZ  . LYS A 44  ? 1.57530 1.34590 1.59320 0.05920  -0.11510 -0.05910 44  LYS A NZ  
638  N N   . ILE A 45  ? 0.54770 0.42410 0.58550 0.05840  -0.10210 -0.01710 45  ILE A N   
639  C CA  . ILE A 45  ? 0.55160 0.44380 0.60230 0.06690  -0.10290 -0.01610 45  ILE A CA  
640  C C   . ILE A 45  ? 0.52310 0.42190 0.57110 0.05910  -0.10790 -0.00540 45  ILE A C   
641  O O   . ILE A 45  ? 0.55030 0.44860 0.58570 0.04710  -0.10600 -0.00130 45  ILE A O   
642  C CB  . ILE A 45  ? 0.58420 0.49620 0.63950 0.07100  -0.09230 -0.02470 45  ILE A CB  
643  C CG1 . ILE A 45  ? 0.61590 0.52260 0.67680 0.08360  -0.08940 -0.03500 45  ILE A CG1 
644  C CG2 . ILE A 45  ? 0.58770 0.52170 0.65430 0.07260  -0.09110 -0.02130 45  ILE A CG2 
645  C CD1 . ILE A 45  ? 0.73400 0.64850 0.78850 0.08390  -0.07910 -0.04400 45  ILE A CD1 
657  N N   . LYS A 46  ? 0.57950 0.48430 0.63950 0.06620  -0.11480 -0.00100 46  LYS A N   
658  C CA  . LYS A 46  ? 0.55950 0.47150 0.61620 0.05920  -0.12070 0.00840  46  LYS A CA  
659  C C   . LYS A 46  ? 0.53870 0.47630 0.60450 0.05910  -0.11510 0.00550  46  LYS A C   
660  O O   . LYS A 46  ? 0.59470 0.54520 0.67500 0.06790  -0.10930 -0.00160 46  LYS A O   
661  C CB  . LYS A 46  ? 0.58400 0.48750 0.64800 0.06580  -0.13380 0.01630  46  LYS A CB  
662  C CG  . LYS A 46  ? 0.59260 0.46840 0.64490 0.06300  -0.14110 0.02270  46  LYS A CG  
663  C CD  . LYS A 46  ? 0.63470 0.50250 0.69160 0.06800  -0.15550 0.03280  46  LYS A CD  
664  C CE  . LYS A 46  ? 0.73010 0.56900 0.78290 0.07090  -0.16340 0.03750  46  LYS A CE  
665  N NZ  . LYS A 46  ? 0.85510 0.67540 0.88650 0.05710  -0.16110 0.04260  46  LYS A NZ  
679  N N   . PRO A 47  ? 0.56190 0.50710 0.61930 0.04880  -0.11620 0.01060  47  PRO A N   
680  C CA  . PRO A 47  ? 0.55630 0.52420 0.62230 0.04720  -0.11110 0.00780  47  PRO A CA  
681  C C   . PRO A 47  ? 0.57850 0.56250 0.66830 0.05800  -0.11420 0.00680  47  PRO A C   
682  O O   . PRO A 47  ? 0.62040 0.60150 0.71810 0.06310  -0.12540 0.01230  47  PRO A O   
683  C CB  . PRO A 47  ? 0.56010 0.52830 0.61250 0.03550  -0.11630 0.01470  47  PRO A CB  
684  C CG  . PRO A 47  ? 0.52540 0.47340 0.55760 0.02830  -0.11580 0.01760  47  PRO A CG  
685  C CD  . PRO A 47  ? 0.54090 0.47340 0.57840 0.03710  -0.12030 0.01830  47  PRO A CD  
693  N N   . HIS A 48  ? 0.63110 0.63230 0.73280 0.06140  -0.10420 -0.00010 48  HIS A N   
694  C CA  . HIS A 48  ? 0.65060 0.67270 0.77680 0.06910  -0.10470 -0.00100 48  HIS A CA  
695  C C   . HIS A 48  ? 0.58100 0.62070 0.71130 0.06010  -0.10560 0.00200  48  HIS A C   
696  O O   . HIS A 48  ? 0.54340 0.58150 0.65840 0.04940  -0.10120 0.00180  48  HIS A O   
697  C CB  . HIS A 48  ? 0.60250 0.63510 0.74070 0.07820  -0.09210 -0.00990 48  HIS A CB  
698  C CG  . HIS A 48  ? 0.68420 0.69940 0.81660 0.08670  -0.08970 -0.01540 48  HIS A CG  
699  N ND1 . HIS A 48  ? 0.77120 0.76460 0.89580 0.08860  -0.09940 -0.01200 48  HIS A ND1 
700  C CD2 . HIS A 48  ? 0.79440 0.81040 0.92770 0.09410  -0.07910 -0.02420 48  HIS A CD2 
701  C CE1 . HIS A 48  ? 0.81290 0.79380 0.93490 0.09640  -0.09530 -0.01910 48  HIS A CE1 
702  N NE2 . HIS A 48  ? 0.92500 0.91930 1.05130 0.10010  -0.08310 -0.02700 48  HIS A NE2 
710  N N   . ASN A 49  ? 0.53830 0.59540 0.69140 0.06490  -0.11150 0.00420  49  ASN A N   
711  C CA  . ASN A 49  ? 0.54920 0.62510 0.71100 0.05700  -0.11260 0.00600  49  ASN A CA  
712  C C   . ASN A 49  ? 0.50910 0.59460 0.66880 0.05150  -0.09800 0.00070  49  ASN A C   
713  O O   . ASN A 49  ? 0.49640 0.58460 0.64740 0.04040  -0.09750 0.00190  49  ASN A O   
714  C CB  . ASN A 49  ? 0.62760 0.72420 0.82080 0.06530  -0.11880 0.00740  49  ASN A CB  
715  C CG  . ASN A 49  ? 0.69650 0.78530 0.89210 0.06900  -0.13630 0.01430  49  ASN A CG  
716  O OD1 . ASN A 49  ? 0.79050 0.86230 0.96320 0.06130  -0.14500 0.01970  49  ASN A OD1 
717  N ND2 . ASN A 49  ? 0.79600 0.89660 1.01900 0.08120  -0.14130 0.01440  49  ASN A ND2 
724  N N   . SER A 50  ? 0.48710 0.57720 0.65430 0.05960  -0.08620 -0.00520 50  SER A N   
725  C CA  . SER A 50  ? 0.44470 0.54330 0.60950 0.05530  -0.07230 -0.00940 50  SER A CA  
726  C C   . SER A 50  ? 0.49540 0.57780 0.63330 0.04580  -0.06900 -0.01000 50  SER A C   
727  O O   . SER A 50  ? 0.48830 0.57610 0.62220 0.04020  -0.05990 -0.01200 50  SER A O   
728  C CB  . SER A 50  ? 0.46130 0.56450 0.63420 0.06660  -0.06090 -0.01570 50  SER A CB  
729  O OG  . SER A 50  ? 0.51800 0.59990 0.67270 0.07100  -0.06010 -0.01920 50  SER A OG  
735  N N   . HIS A 51  ? 0.46940 0.53220 0.58990 0.04390  -0.07590 -0.00820 51  HIS A N   
736  C CA  . HIS A 51  ? 0.45460 0.50330 0.55220 0.03540  -0.07280 -0.00900 51  HIS A CA  
737  C C   . HIS A 51  ? 0.46150 0.51250 0.55170 0.02370  -0.07640 -0.00570 51  HIS A C   
738  O O   . HIS A 51  ? 0.41510 0.45760 0.48920 0.01660  -0.07220 -0.00710 51  HIS A O   
739  C CB  . HIS A 51  ? 0.46690 0.49480 0.55040 0.03700  -0.07820 -0.00790 51  HIS A CB  
740  C CG  . HIS A 51  ? 0.46180 0.48210 0.54650 0.04660  -0.07370 -0.01300 51  HIS A CG  
741  N ND1 . HIS A 51  ? 0.47560 0.47760 0.55260 0.04960  -0.07920 -0.01230 51  HIS A ND1 
742  C CD2 . HIS A 51  ? 0.49250 0.52000 0.58380 0.05360  -0.06430 -0.01910 51  HIS A CD2 
743  C CE1 . HIS A 51  ? 0.53940 0.53710 0.61880 0.05830  -0.07400 -0.01860 51  HIS A CE1 
744  N NE2 . HIS A 51  ? 0.50800 0.52110 0.59490 0.06110  -0.06470 -0.02300 51  HIS A NE2 
752  N N   . GLU A 52  ? 0.43700 0.49890 0.53890 0.02170  -0.08470 -0.00190 52  GLU A N   
753  C CA  . GLU A 52  ? 0.47420 0.53600 0.56690 0.01060  -0.08960 0.00040  52  GLU A CA  
754  C C   . GLU A 52  ? 0.44050 0.50700 0.53030 0.00410  -0.07970 -0.00330 52  GLU A C   
755  O O   . GLU A 52  ? 0.40950 0.48950 0.51440 0.00640  -0.07260 -0.00510 52  GLU A O   
756  C CB  . GLU A 52  ? 0.48880 0.56380 0.59740 0.01000  -0.10060 0.00420  52  GLU A CB  
757  C CG  . GLU A 52  ? 0.52690 0.60060 0.62420 -0.00160 -0.10730 0.00570  52  GLU A CG  
758  C CD  . GLU A 52  ? 0.65250 0.72340 0.74710 -0.00230 -0.12310 0.01120  52  GLU A CD  
759  O OE1 . GLU A 52  ? 0.68400 0.76780 0.80030 0.00370  -0.13080 0.01380  52  GLU A OE1 
760  O OE2 . GLU A 52  ? 0.70760 0.76380 0.77830 -0.00880 -0.12790 0.01310  52  GLU A OE2 
767  N N   . GLY A 53  ? 0.43570 0.49070 0.50610 -0.00410 -0.07900 -0.00410 53  GLY A N   
768  C CA  . GLY A 53  ? 0.43710 0.49350 0.50340 -0.01040 -0.07120 -0.00720 53  GLY A CA  
769  C C   . GLY A 53  ? 0.38060 0.43160 0.44140 -0.00700 -0.06060 -0.01070 53  GLY A C   
770  O O   . GLY A 53  ? 0.43520 0.48590 0.49210 -0.01160 -0.05440 -0.01280 53  GLY A O   
774  N N   . LYS A 54  ? 0.39390 0.43950 0.45380 0.00090  -0.05910 -0.01140 54  LYS A N   
775  C CA  . LYS A 54  ? 0.41050 0.45110 0.46500 0.00460  -0.05040 -0.01510 54  LYS A CA  
776  C C   . LYS A 54  ? 0.42670 0.45240 0.46390 0.00050  -0.05020 -0.01660 54  LYS A C   
777  O O   . LYS A 54  ? 0.40380 0.42200 0.43300 -0.00340 -0.05600 -0.01440 54  LYS A O   
778  C CB  . LYS A 54  ? 0.42330 0.46480 0.48510 0.01510  -0.04910 -0.01660 54  LYS A CB  
779  C CG  . LYS A 54  ? 0.48220 0.54080 0.56270 0.02000  -0.04550 -0.01650 54  LYS A CG  
780  C CD  . LYS A 54  ? 0.54030 0.59930 0.62410 0.03050  -0.03930 -0.02040 54  LYS A CD  
781  C CE  . LYS A 54  ? 0.56030 0.63850 0.66280 0.03460  -0.03290 -0.02050 54  LYS A CE  
782  N NZ  . LYS A 54  ? 0.90650 0.98550 1.01350 0.04640  -0.02800 -0.02490 54  LYS A NZ  
796  N N   . THR A 55  ? 0.39420 0.41640 0.42600 0.00130  -0.04340 -0.01990 55  THR A N   
797  C CA  . THR A 55  ? 0.40310 0.41370 0.42230 -0.00200 -0.04230 -0.02190 55  THR A CA  
798  C C   . THR A 55  ? 0.40660 0.40880 0.42290 0.00400  -0.04250 -0.02400 55  THR A C   
799  O O   . THR A 55  ? 0.40280 0.40710 0.42230 0.01060  -0.03920 -0.02650 55  THR A O   
800  C CB  . THR A 55  ? 0.38660 0.39790 0.40250 -0.00500 -0.03640 -0.02420 55  THR A CB  
801  O OG1 . THR A 55  ? 0.41660 0.43320 0.43480 -0.01130 -0.03690 -0.02280 55  THR A OG1 
802  C CG2 . THR A 55  ? 0.42080 0.42220 0.42720 -0.00730 -0.03550 -0.02670 55  THR A CG2 
810  N N   . PHE A 56  ? 0.37620 0.36850 0.38560 0.00100  -0.04600 -0.02310 56  PHE A N   
811  C CA  . PHE A 56  ? 0.41150 0.39360 0.41820 0.00470  -0.04740 -0.02500 56  PHE A CA  
812  C C   . PHE A 56  ? 0.41030 0.38610 0.41000 -0.00040 -0.04510 -0.02720 56  PHE A C   
813  O O   . PHE A 56  ? 0.38450 0.36020 0.37980 -0.00740 -0.04430 -0.02570 56  PHE A O   
814  C CB  . PHE A 56  ? 0.40580 0.38090 0.41250 0.00500  -0.05420 -0.02080 56  PHE A CB  
815  C CG  . PHE A 56  ? 0.42140 0.40270 0.43770 0.01150  -0.05760 -0.01890 56  PHE A CG  
816  C CD1 . PHE A 56  ? 0.38100 0.37270 0.40230 0.00910  -0.05970 -0.01560 56  PHE A CD1 
817  C CD2 . PHE A 56  ? 0.42210 0.39950 0.44400 0.02030  -0.05880 -0.02120 56  PHE A CD2 
818  C CE1 . PHE A 56  ? 0.39400 0.39390 0.42800 0.01550  -0.06310 -0.01410 56  PHE A CE1 
819  C CE2 . PHE A 56  ? 0.43910 0.42380 0.47270 0.02730  -0.06140 -0.02010 56  PHE A CE2 
820  C CZ  . PHE A 56  ? 0.44110 0.43790 0.48180 0.02490  -0.06350 -0.01620 56  PHE A CZ  
830  N N   . TYR A 57  ? 0.38900 0.35990 0.38800 0.00320  -0.04420 -0.03120 57  TYR A N   
831  C CA  . TYR A 57  ? 0.37100 0.33620 0.36660 -0.00120 -0.04350 -0.03320 57  TYR A CA  
832  C C   . TYR A 57  ? 0.40370 0.35940 0.39820 -0.00440 -0.04730 -0.03080 57  TYR A C   
833  O O   . TYR A 57  ? 0.42590 0.37540 0.42180 -0.00020 -0.05140 -0.02990 57  TYR A O   
834  C CB  . TYR A 57  ? 0.36390 0.32690 0.35900 0.00350  -0.04280 -0.03840 57  TYR A CB  
835  C CG  . TYR A 57  ? 0.37420 0.34380 0.36800 0.00440  -0.03880 -0.04010 57  TYR A CG  
836  C CD1 . TYR A 57  ? 0.43060 0.40680 0.42480 0.00850  -0.03590 -0.03950 57  TYR A CD1 
837  C CD2 . TYR A 57  ? 0.38170 0.35060 0.37490 0.00150  -0.03800 -0.04230 57  TYR A CD2 
838  C CE1 . TYR A 57  ? 0.43990 0.42010 0.43180 0.00890  -0.03230 -0.04000 57  TYR A CE1 
839  C CE2 . TYR A 57  ? 0.41490 0.38760 0.40630 0.00290  -0.03540 -0.04320 57  TYR A CE2 
840  C CZ  . TYR A 57  ? 0.41900 0.39640 0.40870 0.00630  -0.03260 -0.04160 57  TYR A CZ  
841  O OH  . TYR A 57  ? 0.45150 0.43120 0.43830 0.00710  -0.02980 -0.04130 57  TYR A OH  
851  N N   . VAL A 58  ? 0.40470 0.35880 0.39720 -0.01170 -0.04560 -0.02990 58  VAL A N   
852  C CA  . VAL A 58  ? 0.41670 0.36180 0.40800 -0.01650 -0.04780 -0.02710 58  VAL A CA  
853  C C   . VAL A 58  ? 0.43580 0.38080 0.43070 -0.02040 -0.04530 -0.03070 58  VAL A C   
854  O O   . VAL A 58  ? 0.43730 0.38900 0.43470 -0.01920 -0.04240 -0.03480 58  VAL A O   
855  C CB  . VAL A 58  ? 0.39590 0.34040 0.38070 -0.02290 -0.04750 -0.02090 58  VAL A CB  
856  C CG1 . VAL A 58  ? 0.43930 0.38330 0.42270 -0.01870 -0.05250 -0.01690 58  VAL A CG1 
857  C CG2 . VAL A 58  ? 0.43590 0.38880 0.41770 -0.02760 -0.04180 -0.02230 58  VAL A CG2 
867  N N   . LEU A 59  ? 0.42200 0.35960 0.41840 -0.02550 -0.04660 -0.02860 59  LEU A N   
868  C CA  . LEU A 59  ? 0.42960 0.36950 0.43250 -0.03030 -0.04400 -0.03170 59  LEU A CA  
869  C C   . LEU A 59  ? 0.44470 0.39210 0.44600 -0.03710 -0.03700 -0.02980 59  LEU A C   
870  O O   . LEU A 59  ? 0.46440 0.41120 0.45700 -0.03990 -0.03530 -0.02520 59  LEU A O   
871  C CB  . LEU A 59  ? 0.44510 0.37480 0.45250 -0.03420 -0.04760 -0.03040 59  LEU A CB  
872  C CG  . LEU A 59  ? 0.43570 0.35540 0.44410 -0.02750 -0.05480 -0.03350 59  LEU A CG  
873  C CD1 . LEU A 59  ? 0.49330 0.40150 0.50680 -0.03320 -0.05850 -0.03200 59  LEU A CD1 
874  C CD2 . LEU A 59  ? 0.43640 0.36070 0.44700 -0.02070 -0.05630 -0.04110 59  LEU A CD2 
886  N N   . PRO A 60  ? 0.43730 0.39190 0.44660 -0.03930 -0.03300 -0.03400 60  PRO A N   
887  C CA  . PRO A 60  ? 0.44270 0.40490 0.45060 -0.04440 -0.02530 -0.03370 60  PRO A CA  
888  C C   . PRO A 60  ? 0.47360 0.43340 0.48040 -0.05340 -0.02100 -0.02920 60  PRO A C   
889  O O   . PRO A 60  ? 0.53650 0.50230 0.55270 -0.05810 -0.01570 -0.03110 60  PRO A O   
890  C CB  . PRO A 60  ? 0.42180 0.39230 0.44130 -0.04190 -0.02350 -0.04010 60  PRO A CB  
891  C CG  . PRO A 60  ? 0.48670 0.45370 0.50950 -0.03500 -0.03110 -0.04300 60  PRO A CG  
892  C CD  . PRO A 60  ? 0.45730 0.41420 0.47730 -0.03630 -0.03580 -0.03960 60  PRO A CD  
900  N N   . ASN A 61  ? 0.54060 0.49200 0.53610 -0.05590 -0.02320 -0.02270 61  ASN A N   
901  C CA  . ASN A 61  ? 0.61510 0.56080 0.60690 -0.06460 -0.02020 -0.01650 61  ASN A CA  
902  C C   . ASN A 61  ? 0.57730 0.52520 0.55470 -0.07020 -0.01340 -0.01290 61  ASN A C   
903  O O   . ASN A 61  ? 0.59160 0.53130 0.55760 -0.07590 -0.01340 -0.00520 61  ASN A O   
904  C CB  . ASN A 61  ? 0.68950 0.62130 0.67800 -0.06370 -0.02840 -0.01080 61  ASN A CB  
905  C CG  . ASN A 61  ? 0.75970 0.68680 0.76200 -0.06130 -0.03400 -0.01460 61  ASN A CG  
906  O OD1 . ASN A 61  ? 0.74830 0.66270 0.75000 -0.06140 -0.04010 -0.01100 61  ASN A OD1 
907  N ND2 . ASN A 61  ? 0.58890 0.52540 0.60320 -0.05910 -0.03250 -0.02200 61  ASN A ND2 
914  N N   . ASP A 62  ? 0.55390 0.51130 0.53020 -0.06850 -0.00810 -0.01830 62  ASP A N   
915  C CA  . ASP A 62  ? 0.53010 0.49120 0.49480 -0.07440 0.00070  -0.01790 62  ASP A CA  
916  C C   . ASP A 62  ? 0.54420 0.51690 0.51960 -0.07220 0.00770  -0.02660 62  ASP A C   
917  O O   . ASP A 62  ? 0.47610 0.45300 0.46510 -0.06590 0.00420  -0.03170 62  ASP A O   
918  C CB  . ASP A 62  ? 0.59580 0.55150 0.54100 -0.07400 -0.00320 -0.01420 62  ASP A CB  
919  C CG  . ASP A 62  ? 0.63430 0.59480 0.58010 -0.06730 -0.00610 -0.02010 62  ASP A CG  
920  O OD1 . ASP A 62  ? 0.52010 0.48820 0.47240 -0.06570 -0.00060 -0.02720 62  ASP A OD1 
921  O OD2 . ASP A 62  ? 0.65720 0.61360 0.59700 -0.06400 -0.01410 -0.01700 62  ASP A OD2 
926  N N   . ASP A 63  ? 0.49540 0.48500 0.34750 -0.06430 -0.01190 -0.00470 63  ASP A N   
927  C CA  . ASP A 63  ? 0.51750 0.51100 0.37340 -0.06320 -0.00230 -0.01180 63  ASP A CA  
928  C C   . ASP A 63  ? 0.49260 0.48730 0.35740 -0.05860 -0.00200 -0.01610 63  ASP A C   
929  O O   . ASP A 63  ? 0.48390 0.48130 0.35830 -0.05340 0.00400  -0.02010 63  ASP A O   
930  C CB  . ASP A 63  ? 0.49680 0.48870 0.33680 -0.07000 0.00320  -0.01550 63  ASP A CB  
931  C CG  . ASP A 63  ? 0.56000 0.55200 0.39040 -0.07590 0.00520  -0.01210 63  ASP A CG  
932  O OD1 . ASP A 63  ? 0.53110 0.52410 0.36760 -0.07490 0.00390  -0.00780 63  ASP A OD1 
933  O OD2 . ASP A 63  ? 0.61430 0.60470 0.42940 -0.08250 0.00840  -0.01400 63  ASP A OD2 
938  N N   . THR A 64  ? 0.48040 0.47310 0.34110 -0.06120 -0.00840 -0.01520 64  THR A N   
939  C CA  . THR A 64  ? 0.43360 0.42640 0.30060 -0.05910 -0.00870 -0.01880 64  THR A CA  
940  C C   . THR A 64  ? 0.44150 0.43940 0.32630 -0.05170 -0.00990 -0.01680 64  THR A C   
941  O O   . THR A 64  ? 0.43740 0.43470 0.32930 -0.04800 -0.00550 -0.02080 64  THR A O   
942  C CB  . THR A 64  ? 0.46540 0.45810 0.32470 -0.06500 -0.01640 -0.01730 64  THR A CB  
943  O OG1 . THR A 64  ? 0.56840 0.55520 0.40940 -0.07240 -0.01470 -0.01970 64  THR A OG1 
944  C CG2 . THR A 64  ? 0.52070 0.51360 0.38540 -0.06510 -0.01670 -0.02070 64  THR A CG2 
952  N N   . LEU A 65  ? 0.42560 0.42700 0.31630 -0.04910 -0.01590 -0.01070 65  LEU A N   
953  C CA  . LEU A 65  ? 0.42540 0.43110 0.33170 -0.04180 -0.01690 -0.00900 65  LEU A CA  
954  C C   . LEU A 65  ? 0.45210 0.45740 0.36480 -0.03800 -0.00980 -0.01120 65  LEU A C   
955  O O   . LEU A 65  ? 0.38090 0.38880 0.30510 -0.03280 -0.00800 -0.01260 65  LEU A O   
956  C CB  . LEU A 65  ? 0.46060 0.46790 0.36900 -0.03880 -0.02450 -0.00230 65  LEU A CB  
957  C CG  . LEU A 65  ? 0.47360 0.48550 0.37890 -0.04060 -0.03270 0.00090  65  LEU A CG  
958  C CD1 . LEU A 65  ? 0.49780 0.50990 0.40450 -0.03490 -0.03970 0.00760  65  LEU A CD1 
959  C CD2 . LEU A 65  ? 0.45770 0.47780 0.37240 -0.04040 -0.03370 -0.00150 65  LEU A CD2 
971  N N   . ARG A 66  ? 0.40970 0.41310 0.31500 -0.04080 -0.00590 -0.01130 66  ARG A N   
972  C CA  . ARG A 66  ? 0.45700 0.46370 0.36930 -0.03780 0.00050  -0.01320 66  ARG A CA  
973  C C   . ARG A 66  ? 0.40700 0.41520 0.32370 -0.03430 0.00670  -0.01930 66  ARG A C   
974  O O   . ARG A 66  ? 0.39600 0.40750 0.32360 -0.02870 0.00930  -0.02030 66  ARG A O   
975  C CB  . ARG A 66  ? 0.45560 0.46280 0.35840 -0.04320 0.00400  -0.01250 66  ARG A CB  
976  C CG  . ARG A 66  ? 0.51500 0.52970 0.42540 -0.04130 0.01060  -0.01420 66  ARG A CG  
977  C CD  . ARG A 66  ? 0.51980 0.53640 0.42060 -0.04880 0.01300  -0.01220 66  ARG A CD  
978  N NE  . ARG A 66  ? 0.52470 0.55190 0.43260 -0.04880 0.01880  -0.01330 66  ARG A NE  
979  C CZ  . ARG A 66  ? 0.50540 0.53390 0.42000 -0.04850 0.01690  -0.01020 66  ARG A CZ  
980  N NH1 . ARG A 66  ? 0.61890 0.63740 0.53440 -0.04650 0.00990  -0.00620 66  ARG A NH1 
981  N NH2 . ARG A 66  ? 0.47650 0.51720 0.39640 -0.05030 0.02220  -0.01130 66  ARG A NH2 
995  N N   . VAL A 67  ? 0.40310 0.40720 0.30980 -0.03740 0.00880  -0.02330 67  VAL A N   
996  C CA  . VAL A 67  ? 0.43430 0.43550 0.34170 -0.03350 0.01440  -0.02920 67  VAL A CA  
997  C C   . VAL A 67  ? 0.39660 0.39530 0.31230 -0.03050 0.01090  -0.02880 67  VAL A C   
998  O O   . VAL A 67  ? 0.41190 0.40990 0.33460 -0.02460 0.01450  -0.03110 67  VAL A O   
999  C CB  . VAL A 67  ? 0.42880 0.42290 0.32020 -0.03810 0.01740  -0.03380 67  VAL A CB  
1000 C CG1 . VAL A 67  ? 0.46060 0.44660 0.34960 -0.03370 0.02220  -0.03980 67  VAL A CG1 
1001 C CG2 . VAL A 67  ? 0.45910 0.45740 0.34270 -0.04060 0.02260  -0.03480 67  VAL A CG2 
1011 N N   . GLU A 68  ? 0.39800 0.39640 0.31280 -0.03440 0.00390  -0.02580 68  GLU A N   
1012 C CA  . GLU A 68  ? 0.37810 0.37700 0.30110 -0.03270 0.00090  -0.02520 68  GLU A CA  
1013 C C   . GLU A 68  ? 0.36170 0.36610 0.29910 -0.02590 0.00110  -0.02270 68  GLU A C   
1014 O O   . GLU A 68  ? 0.39140 0.39430 0.33480 -0.02230 0.00320  -0.02440 68  GLU A O   
1015 C CB  . GLU A 68  ? 0.37860 0.38140 0.30000 -0.03800 -0.00700 -0.02190 68  GLU A CB  
1016 C CG  . GLU A 68  ? 0.41860 0.41510 0.32530 -0.04600 -0.00780 -0.02510 68  GLU A CG  
1017 C CD  . GLU A 68  ? 0.44290 0.44640 0.34730 -0.05180 -0.01620 -0.02110 68  GLU A CD  
1018 O OE1 . GLU A 68  ? 0.40110 0.41420 0.31580 -0.04810 -0.02140 -0.01580 68  GLU A OE1 
1019 O OE2 . GLU A 68  ? 0.44690 0.44610 0.33820 -0.05970 -0.01790 -0.02320 68  GLU A OE2 
1026 N N   . ALA A 69  ? 0.36140 0.37040 0.30240 -0.02460 -0.00100 -0.01870 69  ALA A N   
1027 C CA  . ALA A 69  ? 0.37860 0.39150 0.33140 -0.01880 -0.00100 -0.01650 69  ALA A CA  
1028 C C   . ALA A 69  ? 0.38030 0.39350 0.33690 -0.01490 0.00560  -0.01970 69  ALA A C   
1029 O O   . ALA A 69  ? 0.36470 0.37920 0.33000 -0.01030 0.00640  -0.01990 69  ALA A O   
1030 C CB  . ALA A 69  ? 0.38690 0.40080 0.33920 -0.01890 -0.00460 -0.01180 69  ALA A CB  
1036 N N   . PHE A 70  ? 0.35580 0.36920 0.30600 -0.01640 0.01030  -0.02220 70  PHE A N   
1037 C CA  . PHE A 70  ? 0.37210 0.38900 0.32700 -0.01140 0.01640  -0.02510 70  PHE A CA  
1038 C C   . PHE A 70  ? 0.38010 0.39080 0.33510 -0.00710 0.01880  -0.02890 70  PHE A C   
1039 O O   . PHE A 70  ? 0.37630 0.38870 0.33910 -0.00120 0.02060  -0.02930 70  PHE A O   
1040 C CB  . PHE A 70  ? 0.41230 0.43360 0.36100 -0.01320 0.02170  -0.02740 70  PHE A CB  
1041 C CG  . PHE A 70  ? 0.39100 0.41970 0.34640 -0.00670 0.02760  -0.03000 70  PHE A CG  
1042 C CD1 . PHE A 70  ? 0.40420 0.44220 0.36990 -0.00500 0.02710  -0.02730 70  PHE A CD1 
1043 C CD2 . PHE A 70  ? 0.41510 0.44060 0.36650 -0.00160 0.03290  -0.03510 70  PHE A CD2 
1044 C CE1 . PHE A 70  ? 0.36420 0.41160 0.33730 0.00120  0.03170  -0.02930 70  PHE A CE1 
1045 C CE2 . PHE A 70  ? 0.40670 0.44020 0.36500 0.00630  0.03780  -0.03720 70  PHE A CE2 
1046 C CZ  . PHE A 70  ? 0.37570 0.42170 0.34570 0.00760  0.03700  -0.03410 70  PHE A CZ  
1056 N N   . GLU A 71  ? 0.37450 0.37660 0.31930 -0.01060 0.01860  -0.03150 71  GLU A N   
1057 C CA  . GLU A 71  ? 0.38930 0.38130 0.33070 -0.00770 0.02060  -0.03500 71  GLU A CA  
1058 C C   . GLU A 71  ? 0.37040 0.36240 0.32070 -0.00630 0.01700  -0.03240 71  GLU A C   
1059 O O   . GLU A 71  ? 0.41800 0.40450 0.36980 -0.00140 0.01930  -0.03390 71  GLU A O   
1060 C CB  . GLU A 71  ? 0.42020 0.40130 0.34680 -0.01380 0.02030  -0.03820 71  GLU A CB  
1061 C CG  . GLU A 71  ? 0.57140 0.55040 0.48710 -0.01390 0.02550  -0.04210 71  GLU A CG  
1062 C CD  . GLU A 71  ? 0.78190 0.75840 0.69720 -0.00440 0.03290  -0.04650 71  GLU A CD  
1063 O OE1 . GLU A 71  ? 0.73480 0.72330 0.65570 -0.00050 0.03680  -0.04640 71  GLU A OE1 
1064 O OE2 . GLU A 71  ? 0.73820 0.70090 0.64690 -0.00100 0.03470  -0.04980 71  GLU A OE2 
1071 N N   . TYR A 72  ? 0.37190 0.37010 0.32770 -0.01000 0.01140  -0.02820 72  TYR A N   
1072 C CA  . TYR A 72  ? 0.37470 0.37440 0.33850 -0.00900 0.00840  -0.02600 72  TYR A CA  
1073 C C   . TYR A 72  ? 0.38440 0.39010 0.35930 -0.00280 0.00920  -0.02390 72  TYR A C   
1074 O O   . TYR A 72  ? 0.37450 0.37810 0.35370 0.00040  0.01010  -0.02400 72  TYR A O   
1075 C CB  . TYR A 72  ? 0.37540 0.38120 0.34090 -0.01410 0.00230  -0.02280 72  TYR A CB  
1076 C CG  . TYR A 72  ? 0.35760 0.36570 0.32870 -0.01520 -0.00000 -0.02150 72  TYR A CG  
1077 C CD1 . TYR A 72  ? 0.38130 0.38080 0.34570 -0.01910 0.00150  -0.02420 72  TYR A CD1 
1078 C CD2 . TYR A 72  ? 0.35860 0.37680 0.34020 -0.01260 -0.00330 -0.01780 72  TYR A CD2 
1079 C CE1 . TYR A 72  ? 0.37000 0.37230 0.33870 -0.02160 -0.00030 -0.02290 72  TYR A CE1 
1080 C CE2 . TYR A 72  ? 0.34670 0.36940 0.33360 -0.01370 -0.00460 -0.01680 72  TYR A CE2 
1081 C CZ  . TYR A 72  ? 0.37930 0.39490 0.36010 -0.01890 -0.00310 -0.01920 72  TYR A CZ  
1082 O OH  . TYR A 72  ? 0.37600 0.39690 0.36140 -0.02160 -0.00410 -0.01800 72  TYR A OH  
1092 N N   . TYR A 73  ? 0.35900 0.37110 0.33720 -0.00180 0.00880  -0.02190 73  TYR A N   
1093 C CA  . TYR A 73  ? 0.32930 0.34660 0.31660 0.00240  0.00870  -0.01970 73  TYR A CA  
1094 C C   . TYR A 73  ? 0.34630 0.36720 0.33540 0.00580  0.01300  -0.02110 73  TYR A C   
1095 O O   . TYR A 73  ? 0.34470 0.36950 0.34080 0.00930  0.01310  -0.01990 73  TYR A O   
1096 C CB  . TYR A 73  ? 0.32840 0.34900 0.31710 0.00070  0.00440  -0.01590 73  TYR A CB  
1097 C CG  . TYR A 73  ? 0.35540 0.37660 0.34440 -0.00090 -0.00040 -0.01380 73  TYR A CG  
1098 C CD1 . TYR A 73  ? 0.32370 0.34750 0.31960 0.00180  -0.00200 -0.01280 73  TYR A CD1 
1099 C CD2 . TYR A 73  ? 0.34360 0.36440 0.32590 -0.00490 -0.00350 -0.01270 73  TYR A CD2 
1100 C CE1 . TYR A 73  ? 0.32370 0.35210 0.32130 0.00090  -0.00620 -0.01080 73  TYR A CE1 
1101 C CE2 . TYR A 73  ? 0.32490 0.34950 0.30870 -0.00550 -0.00840 -0.01040 73  TYR A CE2 
1102 C CZ  . TYR A 73  ? 0.35640 0.38590 0.34840 -0.00250 -0.00970 -0.00950 73  TYR A CZ  
1103 O OH  . TYR A 73  ? 0.36430 0.40120 0.35880 -0.00280 -0.01430 -0.00730 73  TYR A OH  
1113 N N   . HIS A 74  ? 0.33040 0.35160 0.31350 0.00490  0.01660  -0.02370 74  HIS A N   
1114 C CA  . HIS A 74  ? 0.32580 0.35490 0.31150 0.00810  0.02110  -0.02500 74  HIS A CA  
1115 C C   . HIS A 74  ? 0.37830 0.41590 0.36820 0.00490  0.01940  -0.02180 74  HIS A C   
1116 O O   . HIS A 74  ? 0.37390 0.41990 0.37020 0.00740  0.02100  -0.02140 74  HIS A O   
1117 C CB  . HIS A 74  ? 0.35820 0.38760 0.34920 0.01570  0.02360  -0.02660 74  HIS A CB  
1118 C CG  . HIS A 74  ? 0.40170 0.42000 0.38530 0.01910  0.02610  -0.03030 74  HIS A CG  
1119 N ND1 . HIS A 74  ? 0.41920 0.43350 0.40400 0.02680  0.02820  -0.03170 74  HIS A ND1 
1120 C CD2 . HIS A 74  ? 0.40870 0.41700 0.38150 0.01560  0.02670  -0.03280 74  HIS A CD2 
1121 C CE1 . HIS A 74  ? 0.41760 0.41800 0.39180 0.02800  0.03020  -0.03500 74  HIS A CE1 
1122 N NE2 . HIS A 74  ? 0.42080 0.41760 0.38760 0.02070  0.02930  -0.03590 74  HIS A NE2 
1131 N N   . THR A 75  ? 0.34050 0.37490 0.32560 -0.00080 0.01580  -0.01920 75  THR A N   
1132 C CA  . THR A 75  ? 0.36620 0.40410 0.35060 -0.00530 0.01420  -0.01610 75  THR A CA  
1133 C C   . THR A 75  ? 0.38120 0.41550 0.35510 -0.01170 0.01310  -0.01490 75  THR A C   
1134 O O   . THR A 75  ? 0.40240 0.43090 0.37090 -0.01250 0.01150  -0.01560 75  THR A O   
1135 C CB  . THR A 75  ? 0.40400 0.43740 0.39200 -0.00410 0.00950  -0.01290 75  THR A CB  
1136 O OG1 . THR A 75  ? 0.40750 0.44080 0.39190 -0.00910 0.00800  -0.01020 75  THR A OG1 
1137 C CG2 . THR A 75  ? 0.45370 0.47930 0.43870 -0.00380 0.00510  -0.01150 75  THR A CG2 
1145 N N   . THR A 76  ? 0.36270 0.40090 0.33280 -0.01730 0.01400  -0.01320 76  THR A N   
1146 C CA  . THR A 76  ? 0.37420 0.40650 0.33260 -0.02440 0.01170  -0.01050 76  THR A CA  
1147 C C   . THR A 76  ? 0.37030 0.39660 0.32520 -0.02830 0.00760  -0.00620 76  THR A C   
1148 O O   . THR A 76  ? 0.40280 0.42490 0.34680 -0.03570 0.00670  -0.00360 76  THR A O   
1149 C CB  . THR A 76  ? 0.34840 0.38860 0.30100 -0.02940 0.01710  -0.01260 76  THR A CB  
1150 O OG1 . THR A 76  ? 0.34200 0.39570 0.30120 -0.03030 0.02150  -0.01350 76  THR A OG1 
1151 C CG2 . THR A 76  ? 0.40480 0.44590 0.35670 -0.02550 0.02070  -0.01720 76  THR A CG2 
1159 N N   . ASP A 77  ? 0.37290 0.39730 0.33470 -0.02400 0.00550  -0.00540 77  ASP A N   
1160 C CA  . ASP A 77  ? 0.41480 0.42890 0.37030 -0.02690 0.00120  -0.00160 77  ASP A CA  
1161 C C   . ASP A 77  ? 0.37260 0.37330 0.31860 -0.02620 -0.00420 0.00150  77  ASP A C   
1162 O O   . ASP A 77  ? 0.36930 0.36930 0.32000 -0.01980 -0.00630 0.00090  77  ASP A O   
1163 C CB  . ASP A 77  ? 0.40280 0.41630 0.36660 -0.02140 -0.00000 -0.00190 77  ASP A CB  
1164 C CG  . ASP A 77  ? 0.52700 0.52940 0.48250 -0.02540 -0.00330 0.00110  77  ASP A CG  
1165 O OD1 . ASP A 77  ? 0.58010 0.57720 0.53860 -0.02070 -0.00530 0.00130  77  ASP A OD1 
1166 O OD2 . ASP A 77  ? 0.56340 0.56090 0.50770 -0.03390 -0.00370 0.00330  77  ASP A OD2 
1171 N N   . PRO A 78  ? 0.42520 0.41550 0.35720 -0.03270 -0.00670 0.00500  78  PRO A N   
1172 C CA  . PRO A 78  ? 0.46500 0.44370 0.38710 -0.03130 -0.01200 0.00820  78  PRO A CA  
1173 C C   . PRO A 78  ? 0.43740 0.40850 0.36250 -0.02200 -0.01710 0.00980  78  PRO A C   
1174 O O   . PRO A 78  ? 0.47680 0.44640 0.40060 -0.01770 -0.02100 0.01120  78  PRO A O   
1175 C CB  . PRO A 78  ? 0.53670 0.50330 0.44160 -0.04040 -0.01360 0.01200  78  PRO A CB  
1176 C CG  . PRO A 78  ? 0.51940 0.49760 0.42680 -0.04860 -0.00750 0.00990  78  PRO A CG  
1177 C CD  . PRO A 78  ? 0.47970 0.46960 0.40360 -0.04260 -0.00470 0.00640  78  PRO A CD  
1185 N N   . SER A 79  ? 0.47200 0.43960 0.40080 -0.01890 -0.01720 0.00950  79  SER A N   
1186 C CA  . SER A 79  ? 0.43000 0.39050 0.36060 -0.00950 -0.02130 0.01080  79  SER A CA  
1187 C C   . SER A 79  ? 0.48140 0.45490 0.42830 -0.00250 -0.01930 0.00760  79  SER A C   
1188 O O   . SER A 79  ? 0.45530 0.42640 0.40550 0.00540  -0.02180 0.00810  79  SER A O   
1189 C CB  . SER A 79  ? 0.51390 0.45890 0.43520 -0.01010 -0.02280 0.01240  79  SER A CB  
1190 O OG  . SER A 79  ? 0.57130 0.52400 0.50060 -0.01280 -0.01870 0.00950  79  SER A OG  
1196 N N   . PHE A 80  ? 0.40070 0.38730 0.35680 -0.00500 -0.01480 0.00420  80  PHE A N   
1197 C CA  . PHE A 80  ? 0.37680 0.37300 0.34610 0.00050  -0.01280 0.00150  80  PHE A CA  
1198 C C   . PHE A 80  ? 0.41320 0.41160 0.38620 0.00660  -0.01630 0.00240  80  PHE A C   
1199 O O   . PHE A 80  ? 0.38670 0.38780 0.36690 0.01240  -0.01660 0.00190  80  PHE A O   
1200 C CB  . PHE A 80  ? 0.36840 0.37480 0.34350 -0.00240 -0.00810 -0.00190 80  PHE A CB  
1201 C CG  . PHE A 80  ? 0.33370 0.34680 0.31960 0.00230  -0.00600 -0.00440 80  PHE A CG  
1202 C CD1 . PHE A 80  ? 0.34750 0.36330 0.33900 0.00380  -0.00340 -0.00570 80  PHE A CD1 
1203 C CD2 . PHE A 80  ? 0.34470 0.36120 0.33410 0.00430  -0.00710 -0.00520 80  PHE A CD2 
1204 C CE1 . PHE A 80  ? 0.31630 0.33640 0.31570 0.00770  -0.00170 -0.00750 80  PHE A CE1 
1205 C CE2 . PHE A 80  ? 0.34030 0.36120 0.33760 0.00720  -0.00520 -0.00710 80  PHE A CE2 
1206 C CZ  . PHE A 80  ? 0.35530 0.37710 0.35710 0.00930  -0.00250 -0.00820 80  PHE A CZ  
1216 N N   . LEU A 81  ? 0.38120 0.38060 0.34990 0.00500  -0.01900 0.00370  81  LEU A N   
1217 C CA  . LEU A 81  ? 0.37720 0.38350 0.35120 0.00980  -0.02240 0.00450  81  LEU A CA  
1218 C C   . LEU A 81  ? 0.38600 0.38750 0.35900 0.01790  -0.02650 0.00740  81  LEU A C   
1219 O O   . LEU A 81  ? 0.40290 0.41340 0.38470 0.02380  -0.02750 0.00720  81  LEU A O   
1220 C CB  . LEU A 81  ? 0.43410 0.44270 0.40220 0.00570  -0.02520 0.00570  81  LEU A CB  
1221 C CG  . LEU A 81  ? 0.49730 0.51450 0.46890 0.00080  -0.02280 0.00240  81  LEU A CG  
1222 C CD1 . LEU A 81  ? 0.51700 0.54420 0.49980 0.00390  -0.02270 0.00100  81  LEU A CD1 
1223 C CD2 . LEU A 81  ? 0.49950 0.51450 0.46970 -0.00390 -0.01670 -0.00110 81  LEU A CD2 
1235 N N   . GLY A 82  ? 0.40160 0.38870 0.36300 0.01830  -0.02870 0.01000  82  GLY A N   
1236 C CA  . GLY A 82  ? 0.43250 0.41120 0.39020 0.02730  -0.03230 0.01240  82  GLY A CA  
1237 C C   . GLY A 82  ? 0.44730 0.42600 0.41150 0.03160  -0.02910 0.01000  82  GLY A C   
1238 O O   . GLY A 82  ? 0.43560 0.41680 0.40400 0.04080  -0.03040 0.01020  82  GLY A O   
1242 N N   . ARG A 83  ? 0.40360 0.38110 0.36880 0.02520  -0.02480 0.00760  83  ARG A N   
1243 C CA  . ARG A 83  ? 0.38270 0.36050 0.35340 0.02820  -0.02200 0.00530  83  ARG A CA  
1244 C C   . ARG A 83  ? 0.39420 0.38840 0.37920 0.03180  -0.01990 0.00320  83  ARG A C   
1245 O O   . ARG A 83  ? 0.36330 0.35940 0.35260 0.03810  -0.01920 0.00240  83  ARG A O   
1246 C CB  . ARG A 83  ? 0.41130 0.38590 0.37940 0.02000  -0.01870 0.00380  83  ARG A CB  
1247 C CG  . ARG A 83  ? 0.53690 0.49370 0.48880 0.01560  -0.02100 0.00620  83  ARG A CG  
1248 C CD  . ARG A 83  ? 0.62670 0.58220 0.57520 0.00610  -0.01830 0.00530  83  ARG A CD  
1249 N NE  . ARG A 83  ? 0.59300 0.56300 0.54870 -0.00000 -0.01490 0.00390  83  ARG A NE  
1250 C CZ  . ARG A 83  ? 0.49690 0.48030 0.46450 0.00050  -0.01130 0.00110  83  ARG A CZ  
1251 N NH1 . ARG A 83  ? 0.43690 0.42250 0.41150 0.00620  -0.01070 -0.00030 83  ARG A NH1 
1252 N NH2 . ARG A 83  ? 0.47850 0.47280 0.45020 -0.00430 -0.00800 -0.00020 83  ARG A NH2 
1266 N N   . TYR A 84  ? 0.35700 0.36220 0.34800 0.02740  -0.01880 0.00230  84  TYR A N   
1267 C CA  . TYR A 84  ? 0.33020 0.34900 0.33230 0.02880  -0.01720 0.00060  84  TYR A CA  
1268 C C   . TYR A 84  ? 0.37160 0.39840 0.37760 0.03570  -0.02060 0.00240  84  TYR A C   
1269 O O   . TYR A 84  ? 0.33930 0.37410 0.35270 0.04010  -0.01920 0.00150  84  TYR A O   
1270 C CB  . TYR A 84  ? 0.34150 0.36620 0.34520 0.02190  -0.01570 -0.00080 84  TYR A CB  
1271 C CG  . TYR A 84  ? 0.35820 0.39440 0.36980 0.02100  -0.01490 -0.00210 84  TYR A CG  
1272 C CD1 . TYR A 84  ? 0.36510 0.40640 0.38380 0.02370  -0.01270 -0.00320 84  TYR A CD1 
1273 C CD2 . TYR A 84  ? 0.35800 0.39920 0.36840 0.01600  -0.01620 -0.00230 84  TYR A CD2 
1274 C CE1 . TYR A 84  ? 0.38320 0.43430 0.40740 0.02100  -0.01180 -0.00410 84  TYR A CE1 
1275 C CE2 . TYR A 84  ? 0.36490 0.41540 0.38060 0.01310  -0.01560 -0.00350 84  TYR A CE2 
1276 C CZ  . TYR A 84  ? 0.43310 0.48830 0.45560 0.01540  -0.01340 -0.00420 84  TYR A CZ  
1277 O OH  . TYR A 84  ? 0.41670 0.48030 0.44270 0.01080  -0.01280 -0.00510 84  TYR A OH  
1287 N N   . MET A 85  ? 0.35150 0.37690 0.35210 0.03700  -0.02500 0.00510  85  MET A N   
1288 C CA  . MET A 85  ? 0.33440 0.37040 0.33980 0.04470  -0.02860 0.00700  85  MET A CA  
1289 C C   . MET A 85  ? 0.36030 0.39010 0.36420 0.05520  -0.02870 0.00740  85  MET A C   
1290 O O   . MET A 85  ? 0.35000 0.39290 0.36250 0.06210  -0.02840 0.00710  85  MET A O   
1291 C CB  . MET A 85  ? 0.37700 0.41350 0.37670 0.04520  -0.03410 0.01030  85  MET A CB  
1292 C CG  . MET A 85  ? 0.35850 0.40210 0.35870 0.03550  -0.03450 0.00970  85  MET A CG  
1293 S SD  . MET A 85  ? 0.39070 0.45910 0.40470 0.03500  -0.03520 0.00900  85  MET A SD  
1294 C CE  . MET A 85  ? 0.37090 0.44070 0.39000 0.02690  -0.02890 0.00480  85  MET A CE  
1304 N N   . SER A 86  ? 0.37830 0.38810 0.37020 0.05600  -0.02890 0.00790  86  SER A N   
1305 C CA  . SER A 86  ? 0.37290 0.37240 0.35990 0.06580  -0.02900 0.00790  86  SER A CA  
1306 C C   . SER A 86  ? 0.37600 0.38400 0.37230 0.06730  -0.02410 0.00460  86  SER A C   
1307 O O   . SER A 86  ? 0.35210 0.36490 0.35150 0.07710  -0.02370 0.00410  86  SER A O   
1308 C CB  . SER A 86  ? 0.45880 0.43320 0.42920 0.06300  -0.02980 0.00870  86  SER A CB  
1309 O OG  . SER A 86  ? 0.51980 0.48120 0.48340 0.07090  -0.02910 0.00770  86  SER A OG  
1315 N N   . ALA A 87  ? 0.34880 0.35900 0.34900 0.05830  -0.02050 0.00240  87  ALA A N   
1316 C CA  . ALA A 87  ? 0.31620 0.33360 0.32390 0.05880  -0.01620 -0.00020 87  ALA A CA  
1317 C C   . ALA A 87  ? 0.34820 0.38710 0.36860 0.06080  -0.01530 -0.00050 87  ALA A C   
1318 O O   . ALA A 87  ? 0.32150 0.36770 0.34670 0.06650  -0.01300 -0.00160 87  ALA A O   
1319 C CB  . ALA A 87  ? 0.32300 0.33760 0.33120 0.04940  -0.01320 -0.00190 87  ALA A CB  
1325 N N   . LEU A 88  ? 0.34140 0.39070 0.36630 0.05570  -0.01710 0.00060  88  LEU A N   
1326 C CA  . LEU A 88  ? 0.32390 0.39420 0.35980 0.05490  -0.01670 0.00060  88  LEU A CA  
1327 C C   . LEU A 88  ? 0.32270 0.40510 0.36330 0.06570  -0.01840 0.00190  88  LEU A C   
1328 O O   . LEU A 88  ? 0.33250 0.43240 0.38250 0.06710  -0.01620 0.00110  88  LEU A O   
1329 C CB  . LEU A 88  ? 0.32380 0.40030 0.36050 0.04690  -0.01920 0.00160  88  LEU A CB  
1330 C CG  . LEU A 88  ? 0.35440 0.45180 0.40050 0.04250  -0.01930 0.00160  88  LEU A CG  
1331 C CD1 . LEU A 88  ? 0.35390 0.45400 0.40390 0.03730  -0.01440 -0.00070 88  LEU A CD1 
1332 C CD2 . LEU A 88  ? 0.34310 0.44330 0.38670 0.03430  -0.02250 0.00240  88  LEU A CD2 
1344 N N   . ASN A 89  ? 0.33040 0.40440 0.36420 0.07370  -0.02250 0.00400  89  ASN A N   
1345 C CA  . ASN A 89  ? 0.32620 0.41180 0.36410 0.08640  -0.02420 0.00520  89  ASN A CA  
1346 C C   . ASN A 89  ? 0.33850 0.42560 0.37900 0.09300  -0.01930 0.00260  89  ASN A C   
1347 O O   . ASN A 89  ? 0.33980 0.44640 0.38920 0.10100  -0.01840 0.00250  89  ASN A O   
1348 C CB  . ASN A 89  ? 0.39690 0.46670 0.42320 0.09550  -0.02930 0.00790  89  ASN A CB  
1349 C CG  . ASN A 89  ? 0.42960 0.51790 0.46240 0.10710  -0.03330 0.01060  89  ASN A CG  
1350 O OD1 . ASN A 89  ? 0.43890 0.55260 0.48380 0.10340  -0.03480 0.01160  89  ASN A OD1 
1351 N ND2 . ASN A 89  ? 0.50840 0.58420 0.53240 0.12130  -0.03540 0.01170  89  ASN A ND2 
1358 N N   . HIS A 90  ? 0.34060 0.40920 0.37350 0.08930  -0.01600 0.00030  90  HIS A N   
1359 C CA  . HIS A 90  ? 0.33090 0.39910 0.36440 0.09390  -0.01120 -0.00240 90  HIS A CA  
1360 C C   . HIS A 90  ? 0.33220 0.41630 0.37580 0.08530  -0.00690 -0.00400 90  HIS A C   
1361 O O   . HIS A 90  ? 0.36830 0.46790 0.41890 0.08950  -0.00360 -0.00510 90  HIS A O   
1362 C CB  . HIS A 90  ? 0.33790 0.37900 0.35720 0.09290  -0.01020 -0.00400 90  HIS A CB  
1363 C CG  . HIS A 90  ? 0.39190 0.41210 0.39730 0.10060  -0.01380 -0.00270 90  HIS A CG  
1364 N ND1 . HIS A 90  ? 0.44780 0.45920 0.44580 0.11360  -0.01320 -0.00380 90  HIS A ND1 
1365 C CD2 . HIS A 90  ? 0.42110 0.42480 0.41620 0.09690  -0.01790 -0.00040 90  HIS A CD2 
1366 C CE1 . HIS A 90  ? 0.50590 0.49470 0.48890 0.11780  -0.01720 -0.00210 90  HIS A CE1 
1367 N NE2 . HIS A 90  ? 0.47890 0.46330 0.46000 0.10710  -0.02020 0.00020  90  HIS A NE2 
1375 N N   . THR A 91  ? 0.32360 0.40270 0.36660 0.07350  -0.00670 -0.00400 91  THR A N   
1376 C CA  . THR A 91  ? 0.29200 0.37960 0.34080 0.06550  -0.00280 -0.00530 91  THR A CA  
1377 C C   . THR A 91  ? 0.30720 0.41930 0.36700 0.06260  -0.00240 -0.00450 91  THR A C   
1378 O O   . THR A 91  ? 0.32620 0.44770 0.39020 0.05820  0.00130  -0.00540 91  THR A O   
1379 C CB  . THR A 91  ? 0.29780 0.37380 0.34260 0.05520  -0.00270 -0.00560 91  THR A CB  
1380 O OG1 . THR A 91  ? 0.30170 0.38140 0.34780 0.04990  -0.00570 -0.00420 91  THR A OG1 
1381 C CG2 . THR A 91  ? 0.30490 0.36030 0.33980 0.05630  -0.00310 -0.00620 91  THR A CG2 
1389 N N   . LYS A 92  ? 0.32280 0.44590 0.38650 0.06410  -0.00650 -0.00250 92  LYS A N   
1390 C CA  . LYS A 92  ? 0.34660 0.49590 0.42100 0.06060  -0.00650 -0.00160 92  LYS A CA  
1391 C C   . LYS A 92  ? 0.37280 0.54020 0.45450 0.06950  -0.00350 -0.00220 92  LYS A C   
1392 O O   . LYS A 92  ? 0.39720 0.58860 0.48840 0.06480  -0.00190 -0.00180 92  LYS A O   
1393 C CB  . LYS A 92  ? 0.37480 0.53260 0.45110 0.05980  -0.01230 0.00080  92  LYS A CB  
1394 C CG  . LYS A 92  ? 0.41770 0.58530 0.49710 0.07330  -0.01560 0.00260  92  LYS A CG  
1395 C CD  . LYS A 92  ? 0.52080 0.69000 0.59830 0.07200  -0.02230 0.00550  92  LYS A CD  
1396 C CE  . LYS A 92  ? 0.54960 0.72310 0.62710 0.08770  -0.02620 0.00780  92  LYS A CE  
1397 N NZ  . LYS A 92  ? 0.47200 0.64650 0.54640 0.08740  -0.03330 0.01110  92  LYS A NZ  
1411 N N   . LYS A 93  ? 0.35300 0.50920 0.42960 0.08160  -0.00210 -0.00340 93  LYS A N   
1412 C CA  . LYS A 93  ? 0.33980 0.51120 0.42170 0.09160  0.00170  -0.00470 93  LYS A CA  
1413 C C   . LYS A 93  ? 0.34960 0.51180 0.42700 0.08930  0.00760  -0.00740 93  LYS A C   
1414 O O   . LYS A 93  ? 0.38310 0.55880 0.46430 0.09580  0.01190  -0.00900 93  LYS A O   
1415 C CB  . LYS A 93  ? 0.42750 0.59200 0.50470 0.10860  -0.00060 -0.00450 93  LYS A CB  
1416 C CG  . LYS A 93  ? 0.46420 0.64160 0.54640 0.11380  -0.00670 -0.00130 93  LYS A CG  
1417 C CD  . LYS A 93  ? 0.74470 0.90900 0.81860 0.13150  -0.00970 -0.00060 93  LYS A CD  
1418 C CE  . LYS A 93  ? 0.78740 0.91330 0.84310 0.13170  -0.01130 -0.00110 93  LYS A CE  
1419 N NZ  . LYS A 93  ? 0.75260 0.86760 0.80190 0.13170  -0.01830 0.00240  93  LYS A NZ  
1433 N N   . TRP A 94  ? 0.31380 0.45470 0.38290 0.08060  0.00780  -0.00800 94  TRP A N   
1434 C CA  . TRP A 94  ? 0.33530 0.46940 0.40050 0.07640  0.01260  -0.00990 94  TRP A CA  
1435 C C   . TRP A 94  ? 0.34170 0.49670 0.41510 0.06720  0.01590  -0.00940 94  TRP A C   
1436 O O   . TRP A 94  ? 0.32800 0.49810 0.40850 0.06050  0.01390  -0.00770 94  TRP A O   
1437 C CB  . TRP A 94  ? 0.32180 0.43220 0.37800 0.06900  0.01130  -0.01000 94  TRP A CB  
1438 C CG  . TRP A 94  ? 0.32330 0.41140 0.36900 0.07490  0.00900  -0.01070 94  TRP A CG  
1439 C CD1 . TRP A 94  ? 0.33460 0.41650 0.37540 0.08650  0.00810  -0.01140 94  TRP A CD1 
1440 C CD2 . TRP A 94  ? 0.30050 0.36900 0.33830 0.06890  0.00740  -0.01070 94  TRP A CD2 
1441 N NE1 . TRP A 94  ? 0.35180 0.40940 0.38050 0.08640  0.00590  -0.01180 94  TRP A NE1 
1442 C CE2 . TRP A 94  ? 0.30560 0.35690 0.33340 0.07540  0.00550  -0.01130 94  TRP A CE2 
1443 C CE3 . TRP A 94  ? 0.28990 0.35390 0.32740 0.05910  0.00750  -0.01020 94  TRP A CE3 
1444 C CZ2 . TRP A 94  ? 0.30570 0.33850 0.32450 0.07070  0.00370  -0.01130 94  TRP A CZ2 
1445 C CZ3 . TRP A 94  ? 0.30860 0.35590 0.33860 0.05640  0.00580  -0.01040 94  TRP A CZ3 
1446 C CH2 . TRP A 94  ? 0.31350 0.34680 0.33490 0.06120  0.00400  -0.01080 94  TRP A CH2 
1457 N N   . LYS A 95  ? 0.31420 0.46880 0.38490 0.06560  0.02080  -0.01090 95  LYS A N   
1458 C CA  . LYS A 95  ? 0.34740 0.51720 0.42240 0.05510  0.02420  -0.01020 95  LYS A CA  
1459 C C   . LYS A 95  ? 0.32500 0.47530 0.39140 0.04470  0.02450  -0.00980 95  LYS A C   
1460 O O   . LYS A 95  ? 0.34270 0.47270 0.40060 0.04750  0.02420  -0.01080 95  LYS A O   
1461 C CB  . LYS A 95  ? 0.32640 0.51170 0.40380 0.06060  0.03000  -0.01190 95  LYS A CB  
1462 C CG  . LYS A 95  ? 0.37820 0.58810 0.46560 0.07200  0.03070  -0.01230 95  LYS A CG  
1463 C CD  . LYS A 95  ? 0.45990 0.68830 0.55750 0.06820  0.02640  -0.00980 95  LYS A CD  
1464 C CE  . LYS A 95  ? 0.64800 0.91130 0.75870 0.07600  0.02820  -0.00960 95  LYS A CE  
1465 N NZ  . LYS A 95  ? 0.78640 1.07600 0.90740 0.06300  0.02660  -0.00710 95  LYS A NZ  
1479 N N   . TYR A 96  ? 0.32250 0.47900 0.39020 0.03260  0.02480  -0.00820 96  TYR A N   
1480 C CA  . TYR A 96  ? 0.33530 0.47280 0.39420 0.02340  0.02450  -0.00740 96  TYR A CA  
1481 C C   . TYR A 96  ? 0.34350 0.48840 0.40010 0.01410  0.02850  -0.00650 96  TYR A C   
1482 O O   . TYR A 96  ? 0.35220 0.50150 0.40830 0.00300  0.02820  -0.00490 96  TYR A O   
1483 C CB  . TYR A 96  ? 0.32250 0.45300 0.38070 0.01730  0.02030  -0.00640 96  TYR A CB  
1484 C CG  . TYR A 96  ? 0.31610 0.43960 0.37550 0.02560  0.01650  -0.00700 96  TYR A CG  
1485 C CD1 . TYR A 96  ? 0.33170 0.43550 0.38460 0.02980  0.01550  -0.00770 96  TYR A CD1 
1486 C CD2 . TYR A 96  ? 0.31100 0.44880 0.37760 0.02900  0.01390  -0.00650 96  TYR A CD2 
1487 C CE1 . TYR A 96  ? 0.30120 0.39800 0.35350 0.03590  0.01230  -0.00810 96  TYR A CE1 
1488 C CE2 . TYR A 96  ? 0.33020 0.45950 0.39570 0.03630  0.01030  -0.00660 96  TYR A CE2 
1489 C CZ  . TYR A 96  ? 0.32270 0.43080 0.38060 0.03910  0.00970  -0.00740 96  TYR A CZ  
1490 O OH  . TYR A 96  ? 0.31430 0.41290 0.36930 0.04470  0.00640  -0.00730 96  TYR A OH  
1500 N N   . PRO A 97  ? 0.33540 0.48140 0.38910 0.01770  0.03260  -0.00740 97  PRO A N   
1501 C CA  . PRO A 97  ? 0.31750 0.47030 0.36760 0.00810  0.03670  -0.00620 97  PRO A CA  
1502 C C   . PRO A 97  ? 0.30740 0.43780 0.34580 -0.00120 0.03540  -0.00430 97  PRO A C   
1503 O O   . PRO A 97  ? 0.32760 0.43750 0.36020 0.00280  0.03260  -0.00450 97  PRO A O   
1504 C CB  . PRO A 97  ? 0.32730 0.48310 0.37520 0.01590  0.04110  -0.00810 97  PRO A CB  
1505 C CG  . PRO A 97  ? 0.33770 0.47560 0.38220 0.02650  0.03820  -0.00980 97  PRO A CG  
1506 C CD  . PRO A 97  ? 0.33010 0.46880 0.38130 0.02950  0.03340  -0.00960 97  PRO A CD  
1514 N N   . GLN A 98  ? 0.34710 0.48230 0.38160 -0.01360 0.03730  -0.00230 98  GLN A N   
1515 C CA  . GLN A 98  ? 0.35230 0.46510 0.37300 -0.02200 0.03670  -0.00020 98  GLN A CA  
1516 C C   . GLN A 98  ? 0.33060 0.43740 0.34350 -0.02050 0.04000  0.00020  98  GLN A C   
1517 O O   . GLN A 98  ? 0.38980 0.51270 0.40350 -0.02450 0.04460  0.00040  98  GLN A O   
1518 C CB  . GLN A 98  ? 0.37000 0.48720 0.38650 -0.03720 0.03740  0.00190  98  GLN A CB  
1519 C CG  . GLN A 98  ? 0.39130 0.51020 0.41180 -0.04100 0.03360  0.00160  98  GLN A CG  
1520 C CD  . GLN A 98  ? 0.43650 0.52910 0.45020 -0.03660 0.02950  0.00120  98  GLN A CD  
1521 O OE1 . GLN A 98  ? 0.43490 0.50450 0.43540 -0.03980 0.02910  0.00260  98  GLN A OE1 
1522 N NE2 . GLN A 98  ? 0.38010 0.47640 0.40220 -0.02900 0.02660  -0.00050 98  GLN A NE2 
1531 N N   . VAL A 99  ? 0.33880 0.42440 0.34410 -0.01500 0.03760  0.00040  99  VAL A N   
1532 C CA  . VAL A 99  ? 0.31770 0.39600 0.31420 -0.01320 0.03970  0.00090  99  VAL A CA  
1533 C C   . VAL A 99  ? 0.37470 0.42970 0.35720 -0.01890 0.03750  0.00410  99  VAL A C   
1534 O O   . VAL A 99  ? 0.38500 0.42450 0.36540 -0.01480 0.03320  0.00450  99  VAL A O   
1535 C CB  . VAL A 99  ? 0.31670 0.39180 0.31600 -0.00100 0.03850  -0.00160 99  VAL A CB  
1536 C CG1 . VAL A 99  ? 0.34940 0.41750 0.33860 -0.00020 0.04050  -0.00130 99  VAL A CG1 
1537 C CG2 . VAL A 99  ? 0.32770 0.42200 0.33890 0.00600  0.04030  -0.00470 99  VAL A CG2 
1547 N N   . ASN A 100 ? 0.37660 0.42920 0.34860 -0.02760 0.04030  0.00660  100 ASN A N   
1548 C CA  . ASN A 100 ? 0.40210 0.43070 0.35810 -0.03300 0.03810  0.01030  100 ASN A CA  
1549 C C   . ASN A 100 ? 0.44060 0.45530 0.39410 -0.03590 0.03450  0.01110  100 ASN A C   
1550 O O   . ASN A 100 ? 0.45170 0.44480 0.39630 -0.03230 0.03090  0.01270  100 ASN A O   
1551 C CB  . ASN A 100 ? 0.41040 0.42410 0.35990 -0.02460 0.03530  0.01100  100 ASN A CB  
1552 C CG  . ASN A 100 ? 0.49700 0.49010 0.42810 -0.03030 0.03420  0.01540  100 ASN A CG  
1553 O OD1 . ASN A 100 ? 0.51970 0.51420 0.44200 -0.04030 0.03770  0.01750  100 ASN A OD1 
1554 N ND2 . ASN A 100 ? 0.50220 0.47640 0.42720 -0.02410 0.02940  0.01710  100 ASN A ND2 
1561 N N   . GLY A 101 ? 0.41890 0.44650 0.37950 -0.04210 0.03550  0.01000  101 GLY A N   
1562 C CA  . GLY A 101 ? 0.45730 0.47210 0.41360 -0.04680 0.03270  0.01030  101 GLY A CA  
1563 C C   . GLY A 101 ? 0.46240 0.47510 0.42780 -0.03680 0.02920  0.00780  101 GLY A C   
1564 O O   . GLY A 101 ? 0.42880 0.42920 0.38940 -0.03970 0.02700  0.00760  101 GLY A O   
1568 N N   . LEU A 102 ? 0.39650 0.41940 0.37300 -0.02570 0.02880  0.00570  102 LEU A N   
1569 C CA  . LEU A 102 ? 0.39530 0.41650 0.37960 -0.01680 0.02560  0.00350  102 LEU A CA  
1570 C C   . LEU A 102 ? 0.37240 0.41530 0.37140 -0.01280 0.02630  0.00100  102 LEU A C   
1571 O O   . LEU A 102 ? 0.35950 0.41800 0.36360 -0.01190 0.02910  0.00040  102 LEU A O   
1572 C CB  . LEU A 102 ? 0.37620 0.38710 0.35850 -0.00720 0.02360  0.00360  102 LEU A CB  
1573 C CG  . LEU A 102 ? 0.42330 0.41320 0.39160 -0.00770 0.02220  0.00650  102 LEU A CG  
1574 C CD1 . LEU A 102 ? 0.49050 0.47690 0.45990 0.00180  0.01980  0.00650  102 LEU A CD1 
1575 C CD2 . LEU A 102 ? 0.50770 0.48180 0.46900 -0.01000 0.02040  0.00690  102 LEU A CD2 
1587 N N   . THR A 103 ? 0.35770 0.40070 0.36230 -0.00970 0.02370  -0.00040 103 THR A N   
1588 C CA  . THR A 103 ? 0.32420 0.38450 0.34110 -0.00420 0.02330  -0.00240 103 THR A CA  
1589 C C   . THR A 103 ? 0.31180 0.36990 0.33110 0.00600  0.02280  -0.00360 103 THR A C   
1590 O O   . THR A 103 ? 0.34890 0.39440 0.36550 0.01000  0.02040  -0.00380 103 THR A O   
1591 C CB  . THR A 103 ? 0.30620 0.36580 0.32640 -0.00500 0.02040  -0.00320 103 THR A CB  
1592 O OG1 . THR A 103 ? 0.36910 0.42660 0.38370 -0.01590 0.02070  -0.00220 103 THR A OG1 
1593 C CG2 . THR A 103 ? 0.36010 0.43750 0.39160 0.00010  0.01970  -0.00450 103 THR A CG2 
1601 N N   . SER A 104 ? 0.32060 0.39140 0.34430 0.00990  0.02520  -0.00460 104 SER A N   
1602 C CA  . SER A 104 ? 0.32500 0.39300 0.34930 0.01890  0.02470  -0.00620 104 SER A CA  
1603 C C   . SER A 104 ? 0.35010 0.42890 0.38260 0.02510  0.02380  -0.00790 104 SER A C   
1604 O O   . SER A 104 ? 0.30620 0.39390 0.34460 0.02280  0.02270  -0.00750 104 SER A O   
1605 C CB  . SER A 104 ? 0.28940 0.35870 0.30860 0.01960  0.02810  -0.00650 104 SER A CB  
1606 O OG  . SER A 104 ? 0.32440 0.38560 0.34060 0.02670  0.02690  -0.00800 104 SER A OG  
1612 N N   . ILE A 105 ? 0.32440 0.40010 0.35560 0.03300  0.02390  -0.00960 105 ILE A N   
1613 C CA  . ILE A 105 ? 0.32750 0.41010 0.36380 0.04070  0.02300  -0.01100 105 ILE A CA  
1614 C C   . ILE A 105 ? 0.34490 0.43060 0.37850 0.04780  0.02630  -0.01310 105 ILE A C   
1615 O O   . ILE A 105 ? 0.34560 0.41860 0.37080 0.04920  0.02670  -0.01410 105 ILE A O   
1616 C CB  . ILE A 105 ? 0.34790 0.41720 0.38180 0.04400  0.01890  -0.01130 105 ILE A CB  
1617 C CG1 . ILE A 105 ? 0.30660 0.36900 0.34030 0.03770  0.01630  -0.00980 105 ILE A CG1 
1618 C CG2 . ILE A 105 ? 0.33170 0.40770 0.37010 0.05070  0.01730  -0.01180 105 ILE A CG2 
1619 C CD1 . ILE A 105 ? 0.33180 0.38210 0.36220 0.04010  0.01300  -0.01010 105 ILE A CD1 
1631 N N   . LYS A 106 ? 0.33080 0.43360 0.37100 0.05280  0.02850  -0.01390 106 LYS A N   
1632 C CA  . LYS A 106 ? 0.35320 0.45790 0.39030 0.06240  0.03180  -0.01650 106 LYS A CA  
1633 C C   . LYS A 106 ? 0.36240 0.44780 0.39160 0.06990  0.02870  -0.01800 106 LYS A C   
1634 O O   . LYS A 106 ? 0.34760 0.42790 0.37850 0.07120  0.02450  -0.01700 106 LYS A O   
1635 C CB  . LYS A 106 ? 0.33270 0.46170 0.37980 0.06820  0.03420  -0.01690 106 LYS A CB  
1636 C CG  . LYS A 106 ? 0.41360 0.54550 0.45730 0.08030  0.03830  -0.02010 106 LYS A CG  
1637 C CD  . LYS A 106 ? 0.49110 0.64990 0.54660 0.08810  0.04010  -0.02020 106 LYS A CD  
1638 C CE  . LYS A 106 ? 0.69830 0.85900 0.74940 0.10260  0.04450  -0.02390 106 LYS A CE  
1639 N NZ  . LYS A 106 ? 0.82880 0.99820 0.88570 0.11630  0.04230  -0.02400 106 LYS A NZ  
1653 N N   . TRP A 107 ? 0.35290 0.42640 0.37170 0.07390  0.03070  -0.02040 107 TRP A N   
1654 C CA  . TRP A 107 ? 0.35680 0.40900 0.36510 0.07850  0.02760  -0.02190 107 TRP A CA  
1655 C C   . TRP A 107 ? 0.37540 0.42820 0.38490 0.08920  0.02630  -0.02260 107 TRP A C   
1656 O O   . TRP A 107 ? 0.36520 0.43170 0.37880 0.09800  0.02960  -0.02400 107 TRP A O   
1657 C CB  . TRP A 107 ? 0.35860 0.39740 0.35350 0.08050  0.03010  -0.02480 107 TRP A CB  
1658 C CG  . TRP A 107 ? 0.36740 0.38240 0.34970 0.08210  0.02620  -0.02590 107 TRP A CG  
1659 C CD1 . TRP A 107 ? 0.40280 0.40470 0.37960 0.07370  0.02230  -0.02470 107 TRP A CD1 
1660 C CD2 . TRP A 107 ? 0.38270 0.38440 0.35590 0.09190  0.02550  -0.02820 107 TRP A CD2 
1661 N NE1 . TRP A 107 ? 0.40220 0.38480 0.36720 0.07590  0.01950  -0.02600 107 TRP A NE1 
1662 C CE2 . TRP A 107 ? 0.42310 0.40270 0.38440 0.08710  0.02120  -0.02810 107 TRP A CE2 
1663 C CE3 . TRP A 107 ? 0.42830 0.43470 0.40170 0.10470  0.02800  -0.03000 107 TRP A CE3 
1664 C CZ2 . TRP A 107 ? 0.45160 0.41030 0.39880 0.09330  0.01930  -0.02990 107 TRP A CZ2 
1665 C CZ3 . TRP A 107 ? 0.44270 0.42770 0.40240 0.11300  0.02600  -0.03180 107 TRP A CZ3 
1666 C CH2 . TRP A 107 ? 0.45530 0.41530 0.40120 0.10660  0.02170  -0.03170 107 TRP A CH2 
1677 N N   . ALA A 108 ? 0.36520 0.40350 0.37060 0.08870  0.02140  -0.02150 108 ALA A N   
1678 C CA  . ALA A 108 ? 0.37360 0.40580 0.37610 0.09810  0.01880  -0.02150 108 ALA A CA  
1679 C C   . ALA A 108 ? 0.35270 0.36310 0.34570 0.09290  0.01390  -0.02040 108 ALA A C   
1680 O O   . ALA A 108 ? 0.34140 0.35110 0.33690 0.08250  0.01230  -0.01890 108 ALA A O   
1681 C CB  . ALA A 108 ? 0.39440 0.44820 0.41120 0.10060  0.01760  -0.01920 108 ALA A CB  
1687 N N   . ASP A 109 ? 0.41290 0.40540 0.39410 0.10030  0.01180  -0.02120 109 ASP A N   
1688 C CA  . ASP A 109 ? 0.37620 0.35010 0.34860 0.09500  0.00700  -0.01960 109 ASP A CA  
1689 C C   . ASP A 109 ? 0.39380 0.35990 0.36200 0.08250  0.00630  -0.01960 109 ASP A C   
1690 O O   . ASP A 109 ? 0.39940 0.36490 0.37010 0.07430  0.00340  -0.01740 109 ASP A O   
1691 C CB  . ASP A 109 ? 0.36680 0.35220 0.34960 0.09340  0.00370  -0.01620 109 ASP A CB  
1692 C CG  . ASP A 109 ? 0.42040 0.41460 0.40720 0.10570  0.00310  -0.01550 109 ASP A CG  
1693 O OD1 . ASP A 109 ? 0.43200 0.40940 0.40640 0.11530  0.00170  -0.01620 109 ASP A OD1 
1694 O OD2 . ASP A 109 ? 0.42570 0.44350 0.42740 0.10570  0.00360  -0.01410 109 ASP A OD2 
1699 N N   . ASN A 110 ? 0.39080 0.35190 0.35240 0.08150  0.00890  -0.02210 110 ASN A N   
1700 C CA  . ASN A 110 ? 0.41840 0.37210 0.37470 0.07070  0.00760  -0.02200 110 ASN A CA  
1701 C C   . ASN A 110 ? 0.38070 0.35040 0.35090 0.06260  0.00690  -0.01940 110 ASN A C   
1702 O O   . ASN A 110 ? 0.42480 0.39060 0.39340 0.05450  0.00420  -0.01810 110 ASN A O   
1703 C CB  . ASN A 110 ? 0.42560 0.35720 0.36690 0.06650  0.00370  -0.02190 110 ASN A CB  
1704 C CG  . ASN A 110 ? 0.47640 0.38640 0.39990 0.07430  0.00410  -0.02470 110 ASN A CG  
1705 O OD1 . ASN A 110 ? 0.48320 0.39020 0.40090 0.07910  0.00730  -0.02770 110 ASN A OD1 
1706 N ND2 . ASN A 110 ? 0.49320 0.38660 0.40660 0.07620  0.00090  -0.02370 110 ASN A ND2 
1713 N N   . ASN A 111 ? 0.35850 0.34640 0.34150 0.06450  0.00940  -0.01860 111 ASN A N   
1714 C CA  . ASN A 111 ? 0.34920 0.34930 0.34340 0.05790  0.00880  -0.01630 111 ASN A CA  
1715 C C   . ASN A 111 ? 0.34570 0.35110 0.34190 0.05280  0.01050  -0.01600 111 ASN A C   
1716 O O   . ASN A 111 ? 0.34110 0.35600 0.34550 0.04900  0.01080  -0.01430 111 ASN A O   
1717 C CB  . ASN A 111 ? 0.34060 0.35580 0.34580 0.06120  0.00960  -0.01520 111 ASN A CB  
1718 C CG  . ASN A 111 ? 0.35910 0.38780 0.36940 0.06460  0.01380  -0.01610 111 ASN A CG  
1719 O OD1 . ASN A 111 ? 0.34240 0.36850 0.34760 0.06530  0.01640  -0.01770 111 ASN A OD1 
1720 N ND2 . ASN A 111 ? 0.31340 0.35770 0.33350 0.06630  0.01430  -0.01510 111 ASN A ND2 
1727 N N   . SER A 112 ? 0.35760 0.35500 0.34470 0.05220  0.01120  -0.01750 112 SER A N   
1728 C CA  . SER A 112 ? 0.36050 0.36280 0.34880 0.04780  0.01240  -0.01660 112 SER A CA  
1729 C C   . SER A 112 ? 0.32840 0.33210 0.32050 0.04170  0.00940  -0.01430 112 SER A C   
1730 O O   . SER A 112 ? 0.30600 0.31590 0.30250 0.03930  0.01010  -0.01260 112 SER A O   
1731 C CB  . SER A 112 ? 0.34100 0.33430 0.31740 0.04800  0.01330  -0.01870 112 SER A CB  
1732 O OG  . SER A 112 ? 0.36920 0.35090 0.33680 0.04390  0.00970  -0.01900 112 SER A OG  
1738 N N   . TYR A 113 ? 0.32980 0.32780 0.32000 0.03950  0.00620  -0.01400 113 TYR A N   
1739 C CA  . TYR A 113 ? 0.33740 0.33960 0.33230 0.03490  0.00400  -0.01210 113 TYR A CA  
1740 C C   . TYR A 113 ? 0.33570 0.34620 0.34020 0.03550  0.00500  -0.01080 113 TYR A C   
1741 O O   . TYR A 113 ? 0.31960 0.33410 0.32780 0.03380  0.00480  -0.00940 113 TYR A O   
1742 C CB  . TYR A 113 ? 0.34560 0.34200 0.33600 0.03140  0.00090  -0.01220 113 TYR A CB  
1743 C CG  . TYR A 113 ? 0.31940 0.31430 0.31190 0.03200  0.00030  -0.01200 113 TYR A CG  
1744 C CD1 . TYR A 113 ? 0.35160 0.33770 0.33820 0.03590  0.00040  -0.01310 113 TYR A CD1 
1745 C CD2 . TYR A 113 ? 0.33380 0.33540 0.33290 0.02920  -0.00050 -0.01060 113 TYR A CD2 
1746 C CE1 . TYR A 113 ? 0.36020 0.34430 0.34750 0.03650  -0.00080 -0.01230 113 TYR A CE1 
1747 C CE2 . TYR A 113 ? 0.30920 0.30910 0.30880 0.02910  -0.00120 -0.01030 113 TYR A CE2 
1748 C CZ  . TYR A 113 ? 0.34570 0.33670 0.33920 0.03240  -0.00170 -0.01090 113 TYR A CZ  
1749 O OH  . TYR A 113 ? 0.32710 0.31550 0.31980 0.03250  -0.00300 -0.01000 113 TYR A OH  
1759 N N   . LEU A 114 ? 0.32200 0.33440 0.32960 0.03830  0.00610  -0.01130 114 LEU A N   
1760 C CA  . LEU A 114 ? 0.31520 0.33490 0.33030 0.03750  0.00680  -0.01030 114 LEU A CA  
1761 C C   . LEU A 114 ? 0.31790 0.34290 0.33520 0.03680  0.00930  -0.00980 114 LEU A C   
1762 O O   . LEU A 114 ? 0.31530 0.34210 0.33520 0.03410  0.00960  -0.00870 114 LEU A O   
1763 C CB  . LEU A 114 ? 0.32000 0.34200 0.33760 0.04010  0.00640  -0.01060 114 LEU A CB  
1764 C CG  . LEU A 114 ? 0.39500 0.40990 0.40880 0.03960  0.00370  -0.01060 114 LEU A CG  
1765 C CD1 . LEU A 114 ? 0.44330 0.45780 0.45670 0.04400  0.00290  -0.01060 114 LEU A CD1 
1766 C CD2 . LEU A 114 ? 0.35390 0.37130 0.37120 0.03530  0.00280  -0.00960 114 LEU A CD2 
1778 N N   . ALA A 115 ? 0.33470 0.36090 0.34930 0.03890  0.01140  -0.01060 115 ALA A N   
1779 C CA  . ALA A 115 ? 0.35860 0.39000 0.37390 0.03680  0.01420  -0.00980 115 ALA A CA  
1780 C C   . ALA A 115 ? 0.28430 0.31020 0.29600 0.03360  0.01320  -0.00810 115 ALA A C   
1781 O O   . ALA A 115 ? 0.32550 0.35190 0.33780 0.03050  0.01400  -0.00660 115 ALA A O   
1782 C CB  . ALA A 115 ? 0.33450 0.36830 0.34630 0.03990  0.01700  -0.01130 115 ALA A CB  
1788 N N   . THR A 116 ? 0.34830 0.36850 0.35520 0.03420  0.01130  -0.00820 116 THR A N   
1789 C CA  . THR A 116 ? 0.33860 0.35550 0.34240 0.03250  0.01000  -0.00620 116 THR A CA  
1790 C C   . THR A 116 ? 0.32350 0.34010 0.33130 0.03240  0.00820  -0.00510 116 THR A C   
1791 O O   . THR A 116 ? 0.33130 0.34480 0.33710 0.03200  0.00810  -0.00330 116 THR A O   
1792 C CB  . THR A 116 ? 0.38580 0.39920 0.38350 0.03270  0.00790  -0.00640 116 THR A CB  
1793 O OG1 . THR A 116 ? 0.38650 0.39820 0.38130 0.03190  0.00630  -0.00390 116 THR A OG1 
1794 C CG2 . THR A 116 ? 0.41050 0.42310 0.40910 0.03250  0.00520  -0.00740 116 THR A CG2 
1802 N N   . ALA A 117 ? 0.31760 0.33600 0.32970 0.03290  0.00710  -0.00620 117 ALA A N   
1803 C CA  . ALA A 117 ? 0.34010 0.35890 0.35560 0.03300  0.00630  -0.00570 117 ALA A CA  
1804 C C   . ALA A 117 ? 0.31850 0.33570 0.33440 0.03160  0.00820  -0.00530 117 ALA A C   
1805 O O   . ALA A 117 ? 0.32080 0.33360 0.33460 0.03200  0.00820  -0.00440 117 ALA A O   
1806 C CB  . ALA A 117 ? 0.32360 0.34480 0.34210 0.03280  0.00520  -0.00690 117 ALA A CB  
1812 N N   . LEU A 118 ? 0.30560 0.32640 0.32330 0.03000  0.00980  -0.00610 118 LEU A N   
1813 C CA  . LEU A 118 ? 0.32340 0.34450 0.34120 0.02660  0.01120  -0.00580 118 LEU A CA  
1814 C C   . LEU A 118 ? 0.35190 0.36730 0.36350 0.02410  0.01250  -0.00410 118 LEU A C   
1815 O O   . LEU A 118 ? 0.33120 0.33960 0.33860 0.02150  0.01280  -0.00340 118 LEU A O   
1816 C CB  . LEU A 118 ? 0.31860 0.34890 0.34080 0.02570  0.01220  -0.00670 118 LEU A CB  
1817 C CG  . LEU A 118 ? 0.33110 0.36610 0.35410 0.02040  0.01370  -0.00630 118 LEU A CG  
1818 C CD1 . LEU A 118 ? 0.39060 0.41970 0.41200 0.01790  0.01240  -0.00650 118 LEU A CD1 
1819 C CD2 . LEU A 118 ? 0.34120 0.38970 0.37040 0.02110  0.01420  -0.00690 118 LEU A CD2 
1831 N N   . LEU A 119 ? 0.32020 0.33640 0.32910 0.02470  0.01320  -0.00350 119 LEU A N   
1832 C CA  . LEU A 119 ? 0.32240 0.33210 0.32370 0.02190  0.01420  -0.00140 119 LEU A CA  
1833 C C   . LEU A 119 ? 0.33830 0.33720 0.33430 0.02460  0.01200  0.00030  119 LEU A C   
1834 O O   . LEU A 119 ? 0.39030 0.37920 0.37870 0.02230  0.01230  0.00200  119 LEU A O   
1835 C CB  . LEU A 119 ? 0.34830 0.36130 0.34690 0.02240  0.01550  -0.00120 119 LEU A CB  
1836 C CG  . LEU A 119 ? 0.35970 0.38390 0.36220 0.02100  0.01860  -0.00280 119 LEU A CG  
1837 C CD1 . LEU A 119 ? 0.36330 0.38930 0.36270 0.02370  0.01970  -0.00380 119 LEU A CD1 
1838 C CD2 . LEU A 119 ? 0.36450 0.39130 0.36450 0.01420  0.02130  -0.00150 119 LEU A CD2 
1850 N N   . THR A 120 ? 0.34750 0.34850 0.34700 0.02940  0.00970  -0.00020 120 THR A N   
1851 C CA  . THR A 120 ? 0.37450 0.36940 0.37100 0.03370  0.00750  0.00130  120 THR A CA  
1852 C C   . THR A 120 ? 0.35200 0.34010 0.34720 0.03420  0.00810  0.00080  120 THR A C   
1853 O O   . THR A 120 ? 0.35640 0.33320 0.34390 0.03650  0.00770  0.00240  120 THR A O   
1854 C CB  . THR A 120 ? 0.34380 0.34680 0.34590 0.03730  0.00510  0.00060  120 THR A CB  
1855 O OG1 . THR A 120 ? 0.35810 0.36430 0.35840 0.03610  0.00430  0.00090  120 THR A OG1 
1856 C CG2 . THR A 120 ? 0.36220 0.36360 0.36350 0.04280  0.00300  0.00220  120 THR A CG2 
1864 N N   . LEU A 121 ? 0.34130 0.33430 0.34210 0.03250  0.00910  -0.00160 121 LEU A N   
1865 C CA  . LEU A 121 ? 0.37010 0.35610 0.36830 0.03270  0.00970  -0.00260 121 LEU A CA  
1866 C C   . LEU A 121 ? 0.40400 0.37670 0.39190 0.02840  0.01090  -0.00150 121 LEU A C   
1867 O O   . LEU A 121 ? 0.38970 0.34950 0.36990 0.03050  0.01100  -0.00160 121 LEU A O   
1868 C CB  . LEU A 121 ? 0.32860 0.32210 0.33320 0.03000  0.01030  -0.00490 121 LEU A CB  
1869 C CG  . LEU A 121 ? 0.36670 0.36980 0.37870 0.03320  0.00920  -0.00610 121 LEU A CG  
1870 C CD1 . LEU A 121 ? 0.39530 0.40400 0.41140 0.02980  0.00940  -0.00770 121 LEU A CD1 
1871 C CD2 . LEU A 121 ? 0.35540 0.35630 0.36660 0.03830  0.00910  -0.00660 121 LEU A CD2 
1883 N N   . GLN A 122 ? 0.42470 0.39960 0.41110 0.02230  0.01200  -0.00050 122 GLN A N   
1884 C CA  . GLN A 122 ? 0.41490 0.37790 0.39050 0.01550  0.01330  0.00080  122 GLN A CA  
1885 C C   . GLN A 122 ? 0.44480 0.39260 0.40860 0.01780  0.01250  0.00380  122 GLN A C   
1886 O O   . GLN A 122 ? 0.45160 0.38610 0.40340 0.01150  0.01340  0.00540  122 GLN A O   
1887 C CB  . GLN A 122 ? 0.38230 0.35680 0.36130 0.00780  0.01510  0.00090  122 GLN A CB  
1888 C CG  . GLN A 122 ? 0.35660 0.34490 0.34560 0.00560  0.01530  -0.00140 122 GLN A CG  
1889 C CD  . GLN A 122 ? 0.33930 0.34400 0.33480 0.00170  0.01700  -0.00140 122 GLN A CD  
1890 O OE1 . GLN A 122 ? 0.36040 0.36770 0.35270 -0.00650 0.01860  -0.00050 122 GLN A OE1 
1891 N NE2 . GLN A 122 ? 0.36320 0.37860 0.36700 0.00760  0.01690  -0.00230 122 GLN A NE2 
1900 N N   . GLN A 123 ? 0.40210 0.35140 0.36810 0.02610  0.01050  0.00480  123 GLN A N   
1901 C CA  . GLN A 123 ? 0.40210 0.33790 0.35710 0.03000  0.00890  0.00800  123 GLN A CA  
1902 C C   . GLN A 123 ? 0.43740 0.36700 0.39110 0.04060  0.00680  0.00820  123 GLN A C   
1903 O O   . GLN A 123 ? 0.42970 0.34830 0.37430 0.04580  0.00480  0.01120  123 GLN A O   
1904 C CB  . GLN A 123 ? 0.38990 0.33460 0.34710 0.03030  0.00790  0.00990  123 GLN A CB  
1905 C CG  . GLN A 123 ? 0.42930 0.38050 0.38670 0.02140  0.01060  0.00970  123 GLN A CG  
1906 C CD  . GLN A 123 ? 0.41080 0.37090 0.37020 0.02230  0.01010  0.01050  123 GLN A CD  
1907 O OE1 . GLN A 123 ? 0.42280 0.37500 0.37290 0.02330  0.00860  0.01360  123 GLN A OE1 
1908 N NE2 . GLN A 123 ? 0.38270 0.35770 0.35260 0.02210  0.01120  0.00780  123 GLN A NE2 
1917 N N   . ILE A 124 ? 0.43800 0.37490 0.40000 0.04420  0.00730  0.00510  124 ILE A N   
1918 C CA  . ILE A 124 ? 0.43320 0.36740 0.39510 0.05490  0.00610  0.00490  124 ILE A CA  
1919 C C   . ILE A 124 ? 0.43140 0.35590 0.38910 0.05490  0.00830  0.00180  124 ILE A C   
1920 O O   . ILE A 124 ? 0.44800 0.37570 0.40840 0.04690  0.01000  -0.00050 124 ILE A O   
1921 C CB  . ILE A 124 ? 0.40110 0.35680 0.37740 0.06000  0.00460  0.00410  124 ILE A CB  
1922 C CG1 . ILE A 124 ? 0.42390 0.39290 0.41070 0.05470  0.00620  0.00090  124 ILE A CG1 
1923 C CG2 . ILE A 124 ? 0.42680 0.39000 0.40470 0.05950  0.00200  0.00700  124 ILE A CG2 
1924 C CD1 . ILE A 124 ? 0.43080 0.41820 0.42920 0.05810  0.00500  0.00010  124 ILE A CD1 
1936 N N   . GLU A 125 ? 0.46630 0.37870 0.41640 0.06440  0.00820  0.00170  125 GLU A N   
1937 C CA  . GLU A 125 ? 0.45950 0.35970 0.40270 0.06540  0.01050  -0.00170 125 GLU A CA  
1938 C C   . GLU A 125 ? 0.49480 0.41460 0.45200 0.06860  0.01180  -0.00500 125 GLU A C   
1939 O O   . GLU A 125 ? 0.46350 0.39450 0.42760 0.07860  0.01130  -0.00490 125 GLU A O   
1940 C CB  . GLU A 125 ? 0.53700 0.41450 0.46460 0.07570  0.01030  -0.00080 125 GLU A CB  
1941 C CG  . GLU A 125 ? 0.68250 0.54470 0.60040 0.07790  0.01310  -0.00490 125 GLU A CG  
1942 C CD  . GLU A 125 ? 0.78040 0.61950 0.68240 0.09110  0.01310  -0.00450 125 GLU A CD  
1943 O OE1 . GLU A 125 ? 0.72610 0.54740 0.61530 0.09270  0.01090  -0.00060 125 GLU A OE1 
1944 O OE2 . GLU A 125 ? 0.83700 0.67560 0.73860 0.10050  0.01530  -0.00800 125 GLU A OE2 
1951 N N   . LEU A 126 ? 0.46310 0.38750 0.42380 0.05990  0.01340  -0.00760 126 LEU A N   
1952 C CA  . LEU A 126 ? 0.46680 0.40860 0.43920 0.06090  0.01450  -0.01030 126 LEU A CA  
1953 C C   . LEU A 126 ? 0.49660 0.43210 0.46430 0.05310  0.01620  -0.01330 126 LEU A C   
1954 O O   . LEU A 126 ? 0.50500 0.43730 0.47030 0.04330  0.01570  -0.01270 126 LEU A O   
1955 C CB  . LEU A 126 ? 0.43010 0.39310 0.41660 0.05760  0.01280  -0.00890 126 LEU A CB  
1956 C CG  . LEU A 126 ? 0.45480 0.43500 0.45200 0.05810  0.01350  -0.01090 126 LEU A CG  
1957 C CD1 . LEU A 126 ? 0.50640 0.49710 0.50870 0.06790  0.01320  -0.01040 126 LEU A CD1 
1958 C CD2 . LEU A 126 ? 0.46120 0.45480 0.46730 0.05130  0.01200  -0.01020 126 LEU A CD2 
1970 N N   . LYS A 127 ? 0.45650 0.39170 0.42290 0.05710  0.01840  -0.01660 127 LYS A N   
1971 C CA  . LYS A 127 ? 0.46560 0.39690 0.42790 0.04960  0.01970  -0.01950 127 LYS A CA  
1972 C C   . LYS A 127 ? 0.39910 0.35030 0.37340 0.04950  0.02030  -0.02100 127 LYS A C   
1973 O O   . LYS A 127 ? 0.44000 0.40160 0.42030 0.05750  0.02140  -0.02150 127 LYS A O   
1974 C CB  . LYS A 127 ? 0.53240 0.44110 0.47790 0.05290  0.02210  -0.02260 127 LYS A CB  
1975 C CG  . LYS A 127 ? 0.67140 0.55640 0.60110 0.04750  0.02110  -0.02120 127 LYS A CG  
1976 C CD  . LYS A 127 ? 1.01530 0.87270 0.92500 0.05310  0.02320  -0.02390 127 LYS A CD  
1977 C CE  . LYS A 127 ? 1.31870 1.15310 1.21380 0.05480  0.02190  -0.02090 127 LYS A CE  
1978 N NZ  . LYS A 127 ? 1.10370 0.94900 1.00850 0.06370  0.02010  -0.01690 127 LYS A NZ  
1992 N N   . PHE A 128 ? 0.41060 0.36780 0.38810 0.04040  0.01930  -0.02120 128 PHE A N   
1993 C CA  . PHE A 128 ? 0.35880 0.33190 0.34520 0.03890  0.01930  -0.02200 128 PHE A CA  
1994 C C   . PHE A 128 ? 0.40670 0.37450 0.38570 0.03900  0.02190  -0.02570 128 PHE A C   
1995 O O   . PHE A 128 ? 0.43890 0.39000 0.40540 0.03720  0.02300  -0.02790 128 PHE A O   
1996 C CB  . PHE A 128 ? 0.36190 0.34300 0.35390 0.03050  0.01670  -0.02030 128 PHE A CB  
1997 C CG  . PHE A 128 ? 0.35540 0.34440 0.35530 0.03100  0.01470  -0.01730 128 PHE A CG  
1998 C CD1 . PHE A 128 ? 0.36290 0.36330 0.37070 0.03490  0.01430  -0.01630 128 PHE A CD1 
1999 C CD2 . PHE A 128 ? 0.37560 0.36090 0.37400 0.02690  0.01360  -0.01570 128 PHE A CD2 
2000 C CE1 . PHE A 128 ? 0.40670 0.41250 0.41970 0.03500  0.01250  -0.01390 128 PHE A CE1 
2001 C CE2 . PHE A 128 ? 0.38160 0.37370 0.38610 0.02770  0.01230  -0.01330 128 PHE A CE2 
2002 C CZ  . PHE A 128 ? 0.34860 0.34980 0.35970 0.03190  0.01170  -0.01260 128 PHE A CZ  
2012 N N   . ASN A 129 ? 0.37830 0.35980 0.36390 0.04060  0.02310  -0.02660 129 ASN A N   
2013 C CA  . ASN A 129 ? 0.37250 0.35130 0.35130 0.04050  0.02600  -0.03020 129 ASN A CA  
2014 C C   . ASN A 129 ? 0.40340 0.38360 0.38020 0.03060  0.02420  -0.03030 129 ASN A C   
2015 O O   . ASN A 129 ? 0.41240 0.38120 0.37810 0.02710  0.02520  -0.03310 129 ASN A O   
2016 C CB  . ASN A 129 ? 0.45870 0.45260 0.44420 0.04680  0.02890  -0.03110 129 ASN A CB  
2017 C CG  . ASN A 129 ? 0.53830 0.53130 0.52380 0.05860  0.03120  -0.03180 129 ASN A CG  
2018 O OD1 . ASN A 129 ? 0.51340 0.48830 0.48840 0.06340  0.03220  -0.03310 129 ASN A OD1 
2019 N ND2 . ASN A 129 ? 0.55350 0.56580 0.54970 0.06330  0.03200  -0.03070 129 ASN A ND2 
2026 N N   . PRO A 130 ? 0.39100 0.38370 0.37680 0.02620  0.02130  -0.02760 130 PRO A N   
2027 C CA  . PRO A 130 ? 0.36040 0.35450 0.34370 0.01820  0.01900  -0.02730 130 PRO A CA  
2028 C C   . PRO A 130 ? 0.38150 0.36680 0.35970 0.01250  0.01660  -0.02700 130 PRO A C   
2029 O O   . PRO A 130 ? 0.33900 0.32410 0.32120 0.01260  0.01510  -0.02490 130 PRO A O   
2030 C CB  . PRO A 130 ? 0.37570 0.38250 0.36870 0.01670  0.01620  -0.02390 130 PRO A CB  
2031 C CG  . PRO A 130 ? 0.38860 0.40220 0.38840 0.02270  0.01780  -0.02320 130 PRO A CG  
2032 C CD  . PRO A 130 ? 0.40470 0.40970 0.40160 0.02830  0.01970  -0.02450 130 PRO A CD  
2040 N N   . PRO A 131 ? 0.36170 0.34030 0.33030 0.00680  0.01640  -0.02910 131 PRO A N   
2041 C CA  . PRO A 131 ? 0.39110 0.36500 0.35550 -0.00090 0.01340  -0.02840 131 PRO A CA  
2042 C C   . PRO A 131 ? 0.36300 0.35020 0.33860 -0.00320 0.00950  -0.02450 131 PRO A C   
2043 O O   . PRO A 131 ? 0.36800 0.35460 0.34420 -0.00680 0.00820  -0.02330 131 PRO A O   
2044 C CB  . PRO A 131 ? 0.39450 0.36440 0.34860 -0.00740 0.01290  -0.03080 131 PRO A CB  
2045 C CG  . PRO A 131 ? 0.39280 0.35550 0.34020 -0.00150 0.01770  -0.03440 131 PRO A CG  
2046 C CD  . PRO A 131 ? 0.38160 0.35610 0.34130 0.00650  0.01910  -0.03250 131 PRO A CD  
2054 N N   . ALA A 132 ? 0.35340 0.35210 0.33700 -0.00110 0.00790  -0.02250 132 ALA A N   
2055 C CA  . ALA A 132 ? 0.29940 0.30910 0.29230 -0.00130 0.00450  -0.01910 132 ALA A CA  
2056 C C   . ALA A 132 ? 0.34000 0.35010 0.33860 0.00230  0.00550  -0.01790 132 ALA A C   
2057 O O   . ALA A 132 ? 0.34360 0.35910 0.34620 0.00010  0.00390  -0.01630 132 ALA A O   
2058 C CB  . ALA A 132 ? 0.34720 0.36400 0.34440 0.00140  0.00300  -0.01730 132 ALA A CB  
2064 N N   . LEU A 133 ? 0.34800 0.35360 0.34690 0.00780  0.00830  -0.01870 133 LEU A N   
2065 C CA  . LEU A 133 ? 0.30910 0.31440 0.31210 0.01110  0.00890  -0.01740 133 LEU A CA  
2066 C C   . LEU A 133 ? 0.36340 0.35830 0.35930 0.00820  0.01010  -0.01810 133 LEU A C   
2067 O O   . LEU A 133 ? 0.37090 0.36740 0.36910 0.00670  0.00950  -0.01650 133 LEU A O   
2068 C CB  . LEU A 133 ? 0.31890 0.32460 0.32440 0.01760  0.01080  -0.01760 133 LEU A CB  
2069 C CG  . LEU A 133 ? 0.33890 0.35390 0.35080 0.01910  0.00950  -0.01620 133 LEU A CG  
2070 C CD1 . LEU A 133 ? 0.35600 0.37350 0.37000 0.02380  0.01130  -0.01650 133 LEU A CD1 
2071 C CD2 . LEU A 133 ? 0.33190 0.35150 0.34890 0.01910  0.00730  -0.01390 133 LEU A CD2 
2083 N N   . GLN A 134 ? 0.36410 0.34700 0.34980 0.00690  0.01180  -0.02070 134 GLN A N   
2084 C CA  . GLN A 134 ? 0.39960 0.36870 0.37490 0.00240  0.01240  -0.02150 134 GLN A CA  
2085 C C   . GLN A 134 ? 0.40470 0.38060 0.38140 -0.00700 0.00990  -0.01990 134 GLN A C   
2086 O O   . GLN A 134 ? 0.38540 0.35880 0.36040 -0.01060 0.00990  -0.01850 134 GLN A O   
2087 C CB  . GLN A 134 ? 0.42770 0.38110 0.38930 0.00170  0.01440  -0.02510 134 GLN A CB  
2088 C CG  . GLN A 134 ? 0.40190 0.34980 0.36160 0.01180  0.01760  -0.02700 134 GLN A CG  
2089 C CD  . GLN A 134 ? 0.48010 0.41320 0.42540 0.01140  0.02000  -0.03120 134 GLN A CD  
2090 O OE1 . GLN A 134 ? 0.58840 0.51310 0.52390 0.00260  0.01900  -0.03260 134 GLN A OE1 
2091 N NE2 . GLN A 134 ? 0.53830 0.46970 0.48250 0.02080  0.02340  -0.03350 134 GLN A NE2 
2100 N N   . ASP A 135 ? 0.36520 0.35060 0.34430 -0.01140 0.00760  -0.02010 135 ASP A N   
2101 C CA  . ASP A 135 ? 0.34640 0.34140 0.32720 -0.02030 0.00480  -0.01870 135 ASP A CA  
2102 C C   . ASP A 135 ? 0.36960 0.38040 0.36300 -0.01780 0.00390  -0.01570 135 ASP A C   
2103 O O   . ASP A 135 ? 0.39060 0.40670 0.38480 -0.02380 0.00360  -0.01440 135 ASP A O   
2104 C CB  . ASP A 135 ? 0.39140 0.39480 0.37250 -0.02410 0.00190  -0.01910 135 ASP A CB  
2105 C CG  . ASP A 135 ? 0.43250 0.42060 0.39920 -0.02840 0.00280  -0.02250 135 ASP A CG  
2106 O OD1 . ASP A 135 ? 0.44650 0.41670 0.40160 -0.02980 0.00540  -0.02460 135 ASP A OD1 
2107 O OD2 . ASP A 135 ? 0.43060 0.42310 0.39570 -0.03030 0.00090  -0.02310 135 ASP A OD2 
2112 N N   . ALA A 136 ? 0.36300 0.38100 0.36520 -0.00960 0.00370  -0.01470 136 ALA A N   
2113 C CA  . ALA A 136 ? 0.33430 0.36550 0.34670 -0.00620 0.00300  -0.01240 136 ALA A CA  
2114 C C   . ALA A 136 ? 0.33940 0.36530 0.35120 -0.00460 0.00560  -0.01190 136 ALA A C   
2115 O O   . ALA A 136 ? 0.35290 0.38830 0.36960 -0.00580 0.00580  -0.01040 136 ALA A O   
2116 C CB  . ALA A 136 ? 0.32510 0.36110 0.34350 0.00130  0.00200  -0.01180 136 ALA A CB  
2122 N N   . TYR A 137 ? 0.32630 0.33820 0.33210 -0.00130 0.00760  -0.01290 137 TYR A N   
2123 C CA  . TYR A 137 ? 0.33640 0.34190 0.33990 0.00040  0.00940  -0.01190 137 TYR A CA  
2124 C C   . TYR A 137 ? 0.38230 0.38290 0.37860 -0.00830 0.01000  -0.01140 137 TYR A C   
2125 O O   . TYR A 137 ? 0.37860 0.38280 0.37620 -0.00990 0.01090  -0.00960 137 TYR A O   
2126 C CB  . TYR A 137 ? 0.36320 0.35560 0.36130 0.00660  0.01080  -0.01290 137 TYR A CB  
2127 C CG  . TYR A 137 ? 0.34330 0.32980 0.33910 0.00930  0.01180  -0.01120 137 TYR A CG  
2128 C CD1 . TYR A 137 ? 0.39820 0.39450 0.40100 0.01090  0.01160  -0.00950 137 TYR A CD1 
2129 C CD2 . TYR A 137 ? 0.41900 0.38870 0.40410 0.01070  0.01290  -0.01140 137 TYR A CD2 
2130 C CE1 . TYR A 137 ? 0.36920 0.36010 0.36870 0.01270  0.01230  -0.00790 137 TYR A CE1 
2131 C CE2 . TYR A 137 ? 0.48380 0.44740 0.46560 0.01330  0.01330  -0.00930 137 TYR A CE2 
2132 C CZ  . TYR A 137 ? 0.44400 0.41890 0.43320 0.01380  0.01290  -0.00750 137 TYR A CZ  
2133 O OH  . TYR A 137 ? 0.46420 0.43310 0.44900 0.01590  0.01300  -0.00530 137 TYR A OH  
2143 N N   . TYR A 138 ? 0.39820 0.39010 0.38540 -0.01500 0.00960  -0.01290 138 TYR A N   
2144 C CA  . TYR A 138 ? 0.39790 0.38460 0.37650 -0.02580 0.00980  -0.01230 138 TYR A CA  
2145 C C   . TYR A 138 ? 0.39860 0.40740 0.38730 -0.03130 0.00880  -0.01040 138 TYR A C   
2146 O O   . TYR A 138 ? 0.42090 0.43150 0.40760 -0.03690 0.01010  -0.00870 138 TYR A O   
2147 C CB  . TYR A 138 ? 0.46180 0.43590 0.42820 -0.03280 0.00900  -0.01460 138 TYR A CB  
2148 C CG  . TYR A 138 ? 0.52440 0.49160 0.47940 -0.04640 0.00880  -0.01420 138 TYR A CG  
2149 C CD1 . TYR A 138 ? 0.59450 0.53640 0.53260 -0.04930 0.01050  -0.01440 138 TYR A CD1 
2150 C CD2 . TYR A 138 ? 0.55680 0.54270 0.51720 -0.05670 0.00670  -0.01330 138 TYR A CD2 
2151 C CE1 . TYR A 138 ? 0.64680 0.58000 0.57190 -0.06370 0.01020  -0.01390 138 TYR A CE1 
2152 C CE2 . TYR A 138 ? 0.61420 0.59550 0.56380 -0.07120 0.00630  -0.01280 138 TYR A CE2 
2153 C CZ  . TYR A 138 ? 0.65390 0.60770 0.58510 -0.07540 0.00820  -0.01310 138 TYR A CZ  
2154 O OH  . TYR A 138 ? 0.80140 0.74850 0.71950 -0.09170 0.00780  -0.01240 138 TYR A OH  
2164 N N   . ARG A 139 ? 0.37760 0.40410 0.37710 -0.02910 0.00670  -0.01040 139 ARG A N   
2165 C CA  . ARG A 139 ? 0.35840 0.40840 0.36900 -0.03130 0.00590  -0.00860 139 ARG A CA  
2166 C C   . ARG A 139 ? 0.39040 0.44600 0.40740 -0.02470 0.00820  -0.00730 139 ARG A C   
2167 O O   . ARG A 139 ? 0.38920 0.45780 0.40990 -0.02900 0.00950  -0.00600 139 ARG A O   
2168 C CB  . ARG A 139 ? 0.39480 0.45960 0.41440 -0.02710 0.00280  -0.00860 139 ARG A CB  
2169 C CG  . ARG A 139 ? 0.46110 0.52790 0.47600 -0.03610 -0.00010 -0.00920 139 ARG A CG  
2170 C CD  . ARG A 139 ? 0.48480 0.56860 0.50930 -0.03110 -0.00370 -0.00830 139 ARG A CD  
2171 N NE  . ARG A 139 ? 0.76970 0.87820 0.80410 -0.03390 -0.00480 -0.00630 139 ARG A NE  
2172 C CZ  . ARG A 139 ? 0.72690 0.85580 0.77170 -0.02880 -0.00800 -0.00470 139 ARG A CZ  
2173 N NH1 . ARG A 139 ? 0.62300 0.74850 0.66810 -0.02170 -0.01080 -0.00450 139 ARG A NH1 
2174 N NH2 . ARG A 139 ? 0.69700 0.85030 0.75130 -0.03080 -0.00820 -0.00310 139 ARG A NH2 
2188 N N   . ALA A 140 ? 0.37060 0.41780 0.38870 -0.01480 0.00880  -0.00780 140 ALA A N   
2189 C CA  . ALA A 140 ? 0.33030 0.38150 0.35290 -0.00870 0.01060  -0.00690 140 ALA A CA  
2190 C C   . ALA A 140 ? 0.39420 0.43720 0.40920 -0.01390 0.01310  -0.00580 140 ALA A C   
2191 O O   . ALA A 140 ? 0.38080 0.43390 0.39930 -0.01420 0.01500  -0.00470 140 ALA A O   
2192 C CB  . ALA A 140 ? 0.33620 0.37860 0.35930 0.00060  0.01030  -0.00760 140 ALA A CB  
2198 N N   . ARG A 141 ? 0.39980 0.42340 0.40300 -0.01760 0.01330  -0.00600 141 ARG A N   
2199 C CA  . ARG A 141 ? 0.41520 0.42780 0.40830 -0.02330 0.01510  -0.00440 141 ARG A CA  
2200 C C   . ARG A 141 ? 0.45820 0.48360 0.45140 -0.03500 0.01610  -0.00330 141 ARG A C   
2201 O O   . ARG A 141 ? 0.48750 0.51470 0.47770 -0.03910 0.01830  -0.00150 141 ARG A O   
2202 C CB  . ARG A 141 ? 0.46060 0.44770 0.43880 -0.02440 0.01490  -0.00500 141 ARG A CB  
2203 C CG  . ARG A 141 ? 0.49860 0.47670 0.47780 -0.01260 0.01430  -0.00600 141 ARG A CG  
2204 C CD  . ARG A 141 ? 0.53840 0.49200 0.50310 -0.01090 0.01440  -0.00670 141 ARG A CD  
2205 N NE  . ARG A 141 ? 0.66110 0.59750 0.61080 -0.01780 0.01520  -0.00500 141 ARG A NE  
2206 C CZ  . ARG A 141 ? 0.80720 0.72870 0.74310 -0.02700 0.01520  -0.00570 141 ARG A CZ  
2207 N NH1 . ARG A 141 ? 0.71200 0.63410 0.64750 -0.03010 0.01450  -0.00840 141 ARG A NH1 
2208 N NH2 . ARG A 141 ? 0.79460 0.69850 0.71510 -0.03390 0.01580  -0.00370 141 ARG A NH2 
2222 N N   . ALA A 142 ? 0.44600 0.48190 0.44250 -0.04110 0.01440  -0.00410 142 ALA A N   
2223 C CA  . ALA A 142 ? 0.44440 0.49780 0.44310 -0.05290 0.01490  -0.00300 142 ALA A CA  
2224 C C   . ALA A 142 ? 0.44180 0.52310 0.45590 -0.04810 0.01620  -0.00220 142 ALA A C   
2225 O O   . ALA A 142 ? 0.50940 0.60880 0.52670 -0.05690 0.01760  -0.00100 142 ALA A O   
2226 C CB  . ALA A 142 ? 0.44740 0.50530 0.44510 -0.06060 0.01190  -0.00400 142 ALA A CB  
2232 N N   . GLY A 143 ? 0.41890 0.50420 0.44180 -0.03480 0.01600  -0.00300 143 GLY A N   
2233 C CA  . GLY A 143 ? 0.37660 0.48440 0.41190 -0.02810 0.01750  -0.00280 143 GLY A CA  
2234 C C   . GLY A 143 ? 0.41400 0.53530 0.46020 -0.01920 0.01480  -0.00360 143 GLY A C   
2235 O O   . GLY A 143 ? 0.40180 0.53790 0.45670 -0.01080 0.01600  -0.00380 143 GLY A O   
2239 N N   . GLU A 144 ? 0.39560 0.51140 0.44030 -0.02050 0.01130  -0.00410 144 GLU A N   
2240 C CA  . GLU A 144 ? 0.39160 0.51880 0.44480 -0.01300 0.00810  -0.00430 144 GLU A CA  
2241 C C   . GLU A 144 ? 0.36790 0.47560 0.41680 -0.00490 0.00680  -0.00540 144 GLU A C   
2242 O O   . GLU A 144 ? 0.36820 0.46570 0.41220 -0.00740 0.00460  -0.00600 144 GLU A O   
2243 C CB  . GLU A 144 ? 0.43000 0.56800 0.48410 -0.02200 0.00480  -0.00380 144 GLU A CB  
2244 C CG  . GLU A 144 ? 0.52770 0.69370 0.59000 -0.02860 0.00540  -0.00240 144 GLU A CG  
2245 C CD  . GLU A 144 ? 0.80810 0.96980 0.86230 -0.04260 0.00830  -0.00200 144 GLU A CD  
2246 O OE1 . GLU A 144 ? 0.70360 0.88430 0.76350 -0.04560 0.01130  -0.00100 144 GLU A OE1 
2247 O OE2 . GLU A 144 ? 0.95200 1.09110 0.99320 -0.05060 0.00780  -0.00260 144 GLU A OE2 
2254 N N   . ALA A 145 ? 0.33850 0.44220 0.38890 0.00420  0.00840  -0.00570 145 ALA A N   
2255 C CA  . ALA A 145 ? 0.30340 0.38940 0.34900 0.00990  0.00770  -0.00660 145 ALA A CA  
2256 C C   . ALA A 145 ? 0.28280 0.37050 0.33160 0.01800  0.00510  -0.00660 145 ALA A C   
2257 O O   . ALA A 145 ? 0.30760 0.38260 0.35260 0.02210  0.00470  -0.00720 145 ALA A O   
2258 C CB  . ALA A 145 ? 0.33690 0.41460 0.37940 0.01320  0.01050  -0.00680 145 ALA A CB  
2265 N N   . ALA A 146 ? 0.32760 0.43070 0.38270 0.02040  0.00310  -0.00580 146 ALA A N   
2266 C CA  . ALA A 146 ? 0.32940 0.43130 0.38520 0.02870  0.00020  -0.00540 146 ALA A CA  
2267 C C   . ALA A 146 ? 0.29860 0.38640 0.34820 0.02660  -0.00220 -0.00550 146 ALA A C   
2268 O O   . ALA A 146 ? 0.29750 0.37400 0.34300 0.03140  -0.00300 -0.00560 146 ALA A O   
2269 C CB  . ALA A 146 ? 0.33540 0.45720 0.39860 0.03180  -0.00230 -0.00400 146 ALA A CB  
2275 N N   . ASN A 147 ? 0.33340 0.42150 0.38110 0.01870  -0.00330 -0.00550 147 ASN A N   
2276 C CA  . ASN A 147 ? 0.32460 0.40060 0.36590 0.01700  -0.00490 -0.00600 147 ASN A CA  
2277 C C   . ASN A 147 ? 0.32240 0.38340 0.35870 0.01740  -0.00220 -0.00740 147 ASN A C   
2278 O O   . ASN A 147 ? 0.29960 0.35260 0.33260 0.01980  -0.00290 -0.00740 147 ASN A O   
2279 C CB  . ASN A 147 ? 0.37170 0.45050 0.41040 0.00840  -0.00640 -0.00630 147 ASN A CB  
2280 C CG  . ASN A 147 ? 0.35950 0.45300 0.40220 0.00860  -0.01070 -0.00450 147 ASN A CG  
2281 O OD1 . ASN A 147 ? 0.52600 0.61590 0.56520 0.01020  -0.01370 -0.00370 147 ASN A OD1 
2282 N ND2 . ASN A 147 ? 0.42130 0.53230 0.47110 0.00740  -0.01120 -0.00350 147 ASN A ND2 
2289 N N   . PHE A 148 ? 0.32140 0.37950 0.35720 0.01520  0.00070  -0.00810 148 PHE A N   
2290 C CA  . PHE A 148 ? 0.31850 0.36490 0.35050 0.01680  0.00270  -0.00900 148 PHE A CA  
2291 C C   . PHE A 148 ? 0.31590 0.36030 0.34890 0.02300  0.00240  -0.00860 148 PHE A C   
2292 O O   . PHE A 148 ? 0.30000 0.33760 0.33020 0.02410  0.00230  -0.00890 148 PHE A O   
2293 C CB  . PHE A 148 ? 0.28780 0.33090 0.31790 0.01400  0.00530  -0.00920 148 PHE A CB  
2294 C CG  . PHE A 148 ? 0.30860 0.34030 0.33440 0.01600  0.00680  -0.00980 148 PHE A CG  
2295 C CD1 . PHE A 148 ? 0.33830 0.36230 0.35960 0.01530  0.00700  -0.01100 148 PHE A CD1 
2296 C CD2 . PHE A 148 ? 0.34490 0.37480 0.37090 0.01910  0.00790  -0.00910 148 PHE A CD2 
2297 C CE1 . PHE A 148 ? 0.34160 0.35820 0.36010 0.01860  0.00830  -0.01140 148 PHE A CE1 
2298 C CE2 . PHE A 148 ? 0.36170 0.38370 0.38450 0.02150  0.00860  -0.00930 148 PHE A CE2 
2299 C CZ  . PHE A 148 ? 0.37050 0.38680 0.39030 0.02170  0.00880  -0.01030 148 PHE A CZ  
2309 N N   . CYS A 149 ? 0.31400 0.36470 0.35040 0.02680  0.00250  -0.00800 149 CYS A N   
2310 C CA  . CYS A 149 ? 0.31670 0.36240 0.35120 0.03220  0.00230  -0.00800 149 CYS A CA  
2311 C C   . CYS A 149 ? 0.33460 0.37550 0.36590 0.03410  -0.00050 -0.00750 149 CYS A C   
2312 O O   . CYS A 149 ? 0.31400 0.34620 0.34070 0.03470  -0.00090 -0.00760 149 CYS A O   
2313 C CB  . CYS A 149 ? 0.31400 0.36670 0.35130 0.03670  0.00340  -0.00810 149 CYS A CB  
2314 S SG  . CYS A 149 ? 0.32560 0.38090 0.36360 0.03380  0.00720  -0.00850 149 CYS A SG  
2320 N N   . ALA A 150 ? 0.31560 0.36240 0.34850 0.03430  -0.00280 -0.00650 150 ALA A N   
2321 C CA  . ALA A 150 ? 0.30610 0.34690 0.33420 0.03560  -0.00580 -0.00550 150 ALA A CA  
2322 C C   . ALA A 150 ? 0.31960 0.35320 0.34330 0.03020  -0.00540 -0.00590 150 ALA A C   
2323 O O   . ALA A 150 ? 0.32900 0.35450 0.34690 0.03000  -0.00660 -0.00530 150 ALA A O   
2324 C CB  . ALA A 150 ? 0.31080 0.36090 0.34150 0.03670  -0.00880 -0.00400 150 ALA A CB  
2330 N N   . LEU A 151 ? 0.28470 0.32090 0.31030 0.02560  -0.00360 -0.00710 151 LEU A N   
2331 C CA  . LEU A 151 ? 0.33630 0.36720 0.35820 0.02220  -0.00230 -0.00800 151 LEU A CA  
2332 C C   . LEU A 151 ? 0.31660 0.34350 0.33790 0.02330  -0.00070 -0.00850 151 LEU A C   
2333 O O   . LEU A 151 ? 0.34960 0.37360 0.36750 0.02150  -0.00080 -0.00840 151 LEU A O   
2334 C CB  . LEU A 151 ? 0.34120 0.37310 0.36320 0.01850  -0.00050 -0.00960 151 LEU A CB  
2335 C CG  . LEU A 151 ? 0.32960 0.36460 0.34990 0.01480  -0.00230 -0.00950 151 LEU A CG  
2336 C CD1 . LEU A 151 ? 0.34150 0.37400 0.35930 0.01060  -0.00020 -0.01140 151 LEU A CD1 
2337 C CD2 . LEU A 151 ? 0.33210 0.36400 0.34710 0.01320  -0.00370 -0.00920 151 LEU A CD2 
2349 N N   . ILE A 152 ? 0.32210 0.34980 0.34620 0.02550  0.00060  -0.00880 152 ILE A N   
2350 C CA  . ILE A 152 ? 0.33120 0.35620 0.35420 0.02610  0.00130  -0.00890 152 ILE A CA  
2351 C C   . ILE A 152 ? 0.28780 0.30770 0.30580 0.02580  -0.00070 -0.00810 152 ILE A C   
2352 O O   . ILE A 152 ? 0.30970 0.32830 0.32510 0.02300  -0.00080 -0.00800 152 ILE A O   
2353 C CB  . ILE A 152 ? 0.33460 0.36020 0.35940 0.02840  0.00240  -0.00900 152 ILE A CB  
2354 C CG1 . ILE A 152 ? 0.36930 0.39660 0.39610 0.02760  0.00430  -0.00940 152 ILE A CG1 
2355 C CG2 . ILE A 152 ? 0.35820 0.38120 0.38070 0.02840  0.00220  -0.00890 152 ILE A CG2 
2356 C CD1 . ILE A 152 ? 0.34630 0.37370 0.37350 0.02890  0.00550  -0.00900 152 ILE A CD1 
2368 N N   . LEU A 153 ? 0.30910 0.32630 0.32510 0.02890  -0.00230 -0.00740 153 LEU A N   
2369 C CA  . LEU A 153 ? 0.30780 0.31570 0.31610 0.02940  -0.00450 -0.00660 153 LEU A CA  
2370 C C   . LEU A 153 ? 0.30970 0.31460 0.31330 0.02470  -0.00580 -0.00560 153 LEU A C   
2371 O O   . LEU A 153 ? 0.34420 0.34290 0.34130 0.02070  -0.00650 -0.00510 153 LEU A O   
2372 C CB  . LEU A 153 ? 0.31070 0.31650 0.31770 0.03570  -0.00600 -0.00600 153 LEU A CB  
2373 C CG  . LEU A 153 ? 0.31230 0.31990 0.32160 0.04020  -0.00410 -0.00730 153 LEU A CG  
2374 C CD1 . LEU A 153 ? 0.34270 0.35580 0.35490 0.04700  -0.00460 -0.00700 153 LEU A CD1 
2375 C CD2 . LEU A 153 ? 0.32780 0.32330 0.32800 0.04030  -0.00440 -0.00800 153 LEU A CD2 
2387 N N   . ALA A 154 ? 0.32630 0.33600 0.33220 0.02390  -0.00610 -0.00530 154 ALA A N   
2388 C CA  . ALA A 154 ? 0.31040 0.31750 0.31090 0.01920  -0.00700 -0.00440 154 ALA A CA  
2389 C C   . ALA A 154 ? 0.29820 0.30930 0.29960 0.01420  -0.00440 -0.00550 154 ALA A C   
2390 O O   . ALA A 154 ? 0.34730 0.35520 0.34250 0.00930  -0.00470 -0.00460 154 ALA A O   
2391 C CB  . ALA A 154 ? 0.34130 0.35330 0.34360 0.01910  -0.00790 -0.00410 154 ALA A CB  
2397 N N   . TYR A 155 ? 0.30750 0.32610 0.31600 0.01530  -0.00160 -0.00720 155 TYR A N   
2398 C CA  . TYR A 155 ? 0.30860 0.33310 0.31890 0.01280  0.00090  -0.00830 155 TYR A CA  
2399 C C   . TYR A 155 ? 0.35480 0.37950 0.36370 0.01060  0.00040  -0.00760 155 TYR A C   
2400 O O   . TYR A 155 ? 0.34150 0.37110 0.34900 0.00590  0.00130  -0.00750 155 TYR A O   
2401 C CB  . TYR A 155 ? 0.29800 0.32740 0.31440 0.01620  0.00350  -0.01000 155 TYR A CB  
2402 C CG  . TYR A 155 ? 0.29120 0.32060 0.30670 0.01600  0.00480  -0.01140 155 TYR A CG  
2403 C CD1 . TYR A 155 ? 0.33650 0.36830 0.34900 0.01340  0.00670  -0.01250 155 TYR A CD1 
2404 C CD2 . TYR A 155 ? 0.32830 0.35540 0.34480 0.01740  0.00440  -0.01180 155 TYR A CD2 
2405 C CE1 . TYR A 155 ? 0.32450 0.35440 0.33410 0.01290  0.00800  -0.01420 155 TYR A CE1 
2406 C CE2 . TYR A 155 ? 0.32900 0.35460 0.34270 0.01570  0.00530  -0.01320 155 TYR A CE2 
2407 C CZ  . TYR A 155 ? 0.32540 0.35140 0.33510 0.01370  0.00700  -0.01460 155 TYR A CZ  
2408 O OH  . TYR A 155 ? 0.34130 0.36390 0.34620 0.01180  0.00800  -0.01650 155 TYR A OH  
2418 N N   . CYS A 156 ? 0.33240 0.35230 0.34090 0.01310  -0.00100 -0.00730 156 CYS A N   
2419 C CA  . CYS A 156 ? 0.36730 0.38590 0.37280 0.01020  -0.00190 -0.00690 156 CYS A CA  
2420 C C   . CYS A 156 ? 0.37020 0.37720 0.36470 0.00570  -0.00450 -0.00560 156 CYS A C   
2421 O O   . CYS A 156 ? 0.37690 0.38070 0.36630 0.00150  -0.00560 -0.00530 156 CYS A O   
2422 C CB  . CYS A 156 ? 0.34530 0.36230 0.35310 0.01460  -0.00210 -0.00740 156 CYS A CB  
2423 S SG  . CYS A 156 ? 0.36810 0.39510 0.38530 0.01880  0.00040  -0.00830 156 CYS A SG  
2429 N N   . ASN A 157 ? 0.35450 0.35410 0.34350 0.00590  -0.00580 -0.00450 157 ASN A N   
2430 C CA  . ASN A 157 ? 0.36820 0.35300 0.34390 0.00220  -0.00850 -0.00280 157 ASN A CA  
2431 C C   . ASN A 157 ? 0.41210 0.38460 0.38150 0.00570  -0.01020 -0.00320 157 ASN A C   
2432 O O   . ASN A 157 ? 0.41310 0.37400 0.37110 0.00040  -0.01180 -0.00270 157 ASN A O   
2433 C CB  . ASN A 157 ? 0.39650 0.38360 0.36700 -0.00800 -0.00820 -0.00200 157 ASN A CB  
2434 C CG  . ASN A 157 ? 0.50570 0.49850 0.47640 -0.01140 -0.00710 -0.00130 157 ASN A CG  
2435 O OD1 . ASN A 157 ? 0.50840 0.51640 0.48850 -0.01130 -0.00400 -0.00270 157 ASN A OD1 
2436 N ND2 . ASN A 157 ? 0.48420 0.46370 0.44310 -0.01370 -0.00950 0.00080  157 ASN A ND2 
2443 N N   . LYS A 158 ? 0.38150 0.35630 0.35720 0.01400  -0.00950 -0.00420 158 LYS A N   
2444 C CA  . LYS A 158 ? 0.40410 0.36850 0.37430 0.01940  -0.01030 -0.00510 158 LYS A CA  
2445 C C   . LYS A 158 ? 0.37520 0.33550 0.34470 0.02800  -0.01140 -0.00440 158 LYS A C   
2446 O O   . LYS A 158 ? 0.39380 0.36600 0.37310 0.03090  -0.01070 -0.00420 158 LYS A O   
2447 C CB  . LYS A 158 ? 0.37760 0.35190 0.35670 0.02190  -0.00790 -0.00680 158 LYS A CB  
2448 C CG  . LYS A 158 ? 0.39450 0.37350 0.37400 0.01510  -0.00760 -0.00720 158 LYS A CG  
2449 C CD  . LYS A 158 ? 0.40590 0.37030 0.37120 0.00980  -0.00970 -0.00720 158 LYS A CD  
2450 C CE  . LYS A 158 ? 0.49730 0.47030 0.46430 0.00250  -0.00980 -0.00740 158 LYS A CE  
2451 N NZ  . LYS A 158 ? 0.57090 0.55610 0.54300 -0.00420 -0.00950 -0.00610 158 LYS A NZ  
2465 N N   . THR A 159 ? 0.39450 0.33800 0.35170 0.03220  -0.01330 -0.00420 159 THR A N   
2466 C CA  . THR A 159 ? 0.41170 0.35360 0.36920 0.04270  -0.01440 -0.00370 159 THR A CA  
2467 C C   . THR A 159 ? 0.40830 0.35680 0.37210 0.05030  -0.01190 -0.00590 159 THR A C   
2468 O O   . THR A 159 ? 0.38900 0.33590 0.35150 0.04780  -0.01000 -0.00780 159 THR A O   
2469 C CB  . THR A 159 ? 0.42480 0.34410 0.36480 0.04620  -0.01780 -0.00210 159 THR A CB  
2470 O OG1 . THR A 159 ? 0.50230 0.40380 0.42870 0.04410  -0.01770 -0.00370 159 THR A OG1 
2471 C CG2 . THR A 159 ? 0.51480 0.42820 0.44790 0.03880  -0.02050 0.00070  159 THR A CG2 
2479 N N   . VAL A 160 ? 0.40400 0.36140 0.37450 0.05930  -0.01190 -0.00560 160 VAL A N   
2480 C CA  . VAL A 160 ? 0.37690 0.34100 0.35210 0.06720  -0.00910 -0.00770 160 VAL A CA  
2481 C C   . VAL A 160 ? 0.41280 0.35640 0.37270 0.07160  -0.00900 -0.00950 160 VAL A C   
2482 O O   . VAL A 160 ? 0.43430 0.35940 0.38040 0.07540  -0.01180 -0.00850 160 VAL A O   
2483 C CB  . VAL A 160 ? 0.37660 0.35520 0.36080 0.07620  -0.00960 -0.00670 160 VAL A CB  
2484 C CG1 . VAL A 160 ? 0.40810 0.39350 0.39550 0.08550  -0.00630 -0.00890 160 VAL A CG1 
2485 C CG2 . VAL A 160 ? 0.39890 0.39700 0.39690 0.07000  -0.00930 -0.00560 160 VAL A CG2 
2495 N N   . GLY A 161 ? 0.41380 0.35890 0.37410 0.07130  -0.00580 -0.01200 161 GLY A N   
2496 C CA  . GLY A 161 ? 0.43580 0.36040 0.37990 0.07380  -0.00550 -0.01430 161 GLY A CA  
2497 C C   . GLY A 161 ? 0.45180 0.36370 0.38590 0.06210  -0.00680 -0.01460 161 GLY A C   
2498 O O   . GLY A 161 ? 0.45130 0.34980 0.37350 0.06160  -0.00600 -0.01700 161 GLY A O   
2502 N N   . GLU A 162 ? 0.42330 0.34010 0.36150 0.05240  -0.00860 -0.01240 162 GLU A N   
2503 C CA  . GLU A 162 ? 0.42550 0.33440 0.35550 0.04060  -0.01000 -0.01230 162 GLU A CA  
2504 C C   . GLU A 162 ? 0.40040 0.32270 0.33890 0.03650  -0.00790 -0.01360 162 GLU A C   
2505 O O   . GLU A 162 ? 0.40940 0.35030 0.36310 0.03870  -0.00580 -0.01340 162 GLU A O   
2506 C CB  . GLU A 162 ? 0.46420 0.37730 0.39700 0.03250  -0.01210 -0.00950 162 GLU A CB  
2507 C CG  . GLU A 162 ? 0.52390 0.42920 0.44680 0.01990  -0.01380 -0.00900 162 GLU A CG  
2508 C CD  . GLU A 162 ? 0.53040 0.43840 0.45330 0.01230  -0.01540 -0.00640 162 GLU A CD  
2509 O OE1 . GLU A 162 ? 0.54310 0.44850 0.45920 0.00090  -0.01650 -0.00570 162 GLU A OE1 
2510 O OE2 . GLU A 162 ? 0.47500 0.38920 0.40470 0.01690  -0.01540 -0.00490 162 GLU A OE2 
2517 N N   . LEU A 163 ? 0.43860 0.35030 0.36570 0.02990  -0.00880 -0.01490 163 LEU A N   
2518 C CA  . LEU A 163 ? 0.44820 0.37250 0.38230 0.02570  -0.00770 -0.01550 163 LEU A CA  
2519 C C   . LEU A 163 ? 0.40880 0.35130 0.35610 0.01900  -0.00830 -0.01330 163 LEU A C   
2520 O O   . LEU A 163 ? 0.42950 0.37140 0.37550 0.01330  -0.01000 -0.01170 163 LEU A O   
2521 C CB  . LEU A 163 ? 0.45480 0.36450 0.37280 0.01940  -0.00920 -0.01730 163 LEU A CB  
2522 C CG  . LEU A 163 ? 0.50800 0.39750 0.41070 0.02710  -0.00800 -0.02030 163 LEU A CG  
2523 C CD1 . LEU A 163 ? 0.51190 0.38630 0.39730 0.01940  -0.00950 -0.02240 163 LEU A CD1 
2524 C CD2 . LEU A 163 ? 0.52880 0.42960 0.44180 0.03830  -0.00390 -0.02160 163 LEU A CD2 
2536 N N   . GLY A 164 ? 0.38200 0.34030 0.34120 0.02030  -0.00660 -0.01320 164 GLY A N   
2537 C CA  . GLY A 164 ? 0.36230 0.33710 0.33330 0.01630  -0.00670 -0.01150 164 GLY A CA  
2538 C C   . GLY A 164 ? 0.37210 0.35580 0.34640 0.01430  -0.00690 -0.01140 164 GLY A C   
2539 O O   . GLY A 164 ? 0.38070 0.36070 0.35130 0.01730  -0.00600 -0.01260 164 GLY A O   
2543 N N   . ASP A 165 ? 0.32940 0.32600 0.31060 0.00980  -0.00800 -0.00990 165 ASP A N   
2544 C CA  . ASP A 165 ? 0.31440 0.32210 0.30010 0.00870  -0.00890 -0.00900 165 ASP A CA  
2545 C C   . ASP A 165 ? 0.33250 0.35110 0.33030 0.01470  -0.00690 -0.00800 165 ASP A C   
2546 O O   . ASP A 165 ? 0.31270 0.33640 0.31680 0.01570  -0.00570 -0.00760 165 ASP A O   
2547 C CB  . ASP A 165 ? 0.31850 0.33460 0.30330 0.00020  -0.01180 -0.00790 165 ASP A CB  
2548 C CG  . ASP A 165 ? 0.37590 0.40650 0.36640 -0.00020 -0.01350 -0.00650 165 ASP A CG  
2549 O OD1 . ASP A 165 ? 0.36320 0.39020 0.34630 -0.00320 -0.01560 -0.00680 165 ASP A OD1 
2550 O OD2 . ASP A 165 ? 0.34030 0.38570 0.34180 0.00270  -0.01290 -0.00520 165 ASP A OD2 
2555 N N   . VAL A 166 ? 0.33450 0.35480 0.33340 0.01830  -0.00630 -0.00750 166 VAL A N   
2556 C CA  . VAL A 166 ? 0.30190 0.32800 0.30890 0.02340  -0.00450 -0.00650 166 VAL A CA  
2557 C C   . VAL A 166 ? 0.32610 0.36420 0.34020 0.02370  -0.00540 -0.00510 166 VAL A C   
2558 O O   . VAL A 166 ? 0.34140 0.38210 0.36100 0.02680  -0.00350 -0.00510 166 VAL A O   
2559 C CB  . VAL A 166 ? 0.30310 0.32670 0.30720 0.02610  -0.00400 -0.00590 166 VAL A CB  
2560 C CG1 . VAL A 166 ? 0.33280 0.36030 0.34220 0.03010  -0.00300 -0.00420 166 VAL A CG1 
2561 C CG2 . VAL A 166 ? 0.32110 0.33620 0.32070 0.02760  -0.00150 -0.00750 166 VAL A CG2 
2571 N N   . ARG A 167 ? 0.27480 0.32120 0.28870 0.02050  -0.00830 -0.00410 167 ARG A N   
2572 C CA  . ARG A 167 ? 0.28630 0.34770 0.30820 0.02220  -0.00900 -0.00270 167 ARG A CA  
2573 C C   . ARG A 167 ? 0.29400 0.35950 0.31980 0.02030  -0.00720 -0.00370 167 ARG A C   
2574 O O   . ARG A 167 ? 0.33580 0.40770 0.36790 0.02500  -0.00530 -0.00370 167 ARG A O   
2575 C CB  . ARG A 167 ? 0.32570 0.39900 0.34730 0.01790  -0.01280 -0.00140 167 ARG A CB  
2576 C CG  . ARG A 167 ? 0.32300 0.41580 0.35430 0.02180  -0.01370 0.00040  167 ARG A CG  
2577 C CD  . ARG A 167 ? 0.32470 0.43460 0.35830 0.01400  -0.01660 0.00110  167 ARG A CD  
2578 N NE  . ARG A 167 ? 0.39140 0.50260 0.42550 0.00810  -0.01450 -0.00040 167 ARG A NE  
2579 C CZ  . ARG A 167 ? 0.36620 0.48910 0.40840 0.01110  -0.01190 -0.00060 167 ARG A CZ  
2580 N NH1 . ARG A 167 ? 0.34090 0.47760 0.39190 0.02020  -0.01120 0.00030  167 ARG A NH1 
2581 N NH2 . ARG A 167 ? 0.38250 0.50200 0.42250 0.00530  -0.00980 -0.00190 167 ARG A NH2 
2595 N N   . GLU A 168 ? 0.30290 0.36270 0.32320 0.01350  -0.00770 -0.00460 168 GLU A N   
2596 C CA  . GLU A 168 ? 0.28550 0.34750 0.30740 0.01070  -0.00620 -0.00520 168 GLU A CA  
2597 C C   . GLU A 168 ? 0.33360 0.38820 0.35740 0.01610  -0.00330 -0.00620 168 GLU A C   
2598 O O   . GLU A 168 ? 0.31400 0.37450 0.34220 0.01730  -0.00140 -0.00660 168 GLU A O   
2599 C CB  . GLU A 168 ? 0.29430 0.34710 0.30660 0.00220  -0.00780 -0.00560 168 GLU A CB  
2600 C CG  . GLU A 168 ? 0.35530 0.41030 0.36720 -0.00270 -0.00680 -0.00560 168 GLU A CG  
2601 C CD  . GLU A 168 ? 0.39820 0.47220 0.41480 -0.00870 -0.00720 -0.00470 168 GLU A CD  
2602 O OE1 . GLU A 168 ? 0.33410 0.42090 0.35520 -0.00870 -0.00880 -0.00390 168 GLU A OE1 
2603 O OE2 . GLU A 168 ? 0.37500 0.45220 0.39060 -0.01360 -0.00590 -0.00450 168 GLU A OE2 
2610 N N   . THR A 169 ? 0.31390 0.35660 0.33400 0.01880  -0.00290 -0.00670 169 THR A N   
2611 C CA  . THR A 169 ? 0.32850 0.36620 0.35050 0.02270  -0.00070 -0.00740 169 THR A CA  
2612 C C   . THR A 169 ? 0.35400 0.39700 0.38130 0.02750  0.00100  -0.00720 169 THR A C   
2613 O O   . THR A 169 ? 0.34630 0.39000 0.37560 0.02860  0.00270  -0.00800 169 THR A O   
2614 C CB  . THR A 169 ? 0.30950 0.33780 0.32770 0.02470  -0.00050 -0.00780 169 THR A CB  
2615 O OG1 . THR A 169 ? 0.33510 0.35570 0.34640 0.02190  -0.00190 -0.00820 169 THR A OG1 
2616 C CG2 . THR A 169 ? 0.32940 0.35550 0.35010 0.02750  0.00140  -0.00820 169 THR A CG2 
2624 N N   . MET A 170 ? 0.31140 0.35680 0.33950 0.03050  0.00030  -0.00620 170 MET A N   
2625 C CA  . MET A 170 ? 0.33600 0.38340 0.36690 0.03610  0.00160  -0.00580 170 MET A CA  
2626 C C   . MET A 170 ? 0.35180 0.40970 0.38730 0.03740  0.00250  -0.00640 170 MET A C   
2627 O O   . MET A 170 ? 0.35090 0.40690 0.38690 0.04140  0.00480  -0.00740 170 MET A O   
2628 C CB  . MET A 170 ? 0.35590 0.40400 0.38550 0.03920  -0.00020 -0.00400 170 MET A CB  
2629 C CG  . MET A 170 ? 0.37230 0.40990 0.39670 0.03900  -0.00000 -0.00340 170 MET A CG  
2630 S SD  . MET A 170 ? 0.37820 0.40530 0.40010 0.03830  0.00290  -0.00450 170 MET A SD  
2631 C CE  . MET A 170 ? 0.36180 0.38290 0.38110 0.04350  0.00380  -0.00350 170 MET A CE  
2641 N N   . SER A 171 ? 0.31620 0.38530 0.35410 0.03350  0.00100  -0.00600 171 SER A N   
2642 C CA  . SER A 171 ? 0.32270 0.40560 0.36570 0.03400  0.00250  -0.00650 171 SER A CA  
2643 C C   . SER A 171 ? 0.37650 0.45460 0.41800 0.03240  0.00530  -0.00830 171 SER A C   
2644 O O   . SER A 171 ? 0.37600 0.45910 0.41980 0.03670  0.00800  -0.00960 171 SER A O   
2645 C CB  . SER A 171 ? 0.35800 0.45390 0.40260 0.02700  0.00020  -0.00550 171 SER A CB  
2646 O OG  . SER A 171 ? 0.52960 0.64340 0.58050 0.02760  0.00180  -0.00580 171 SER A OG  
2652 N N   . TYR A 172 ? 0.35560 0.42400 0.39240 0.02690  0.00460  -0.00860 172 TYR A N   
2653 C CA  . TYR A 172 ? 0.34670 0.41010 0.38120 0.02520  0.00650  -0.00980 172 TYR A CA  
2654 C C   . TYR A 172 ? 0.37520 0.43080 0.40890 0.03050  0.00840  -0.01110 172 TYR A C   
2655 O O   . TYR A 172 ? 0.39660 0.45230 0.42920 0.03130  0.01080  -0.01260 172 TYR A O   
2656 C CB  . TYR A 172 ? 0.41000 0.46340 0.43890 0.02000  0.00460  -0.00930 172 TYR A CB  
2657 C CG  . TYR A 172 ? 0.44000 0.49630 0.46550 0.01270  0.00340  -0.00860 172 TYR A CG  
2658 C CD1 . TYR A 172 ? 0.47160 0.52980 0.49500 0.00910  0.00480  -0.00890 172 TYR A CD1 
2659 C CD2 . TYR A 172 ? 0.48610 0.54160 0.50830 0.00840  0.00090  -0.00750 172 TYR A CD2 
2660 C CE1 . TYR A 172 ? 0.59770 0.65690 0.61590 0.00110  0.00370  -0.00780 172 TYR A CE1 
2661 C CE2 . TYR A 172 ? 0.52350 0.57910 0.54000 0.00010  -0.00040 -0.00670 172 TYR A CE2 
2662 C CZ  . TYR A 172 ? 0.51900 0.57630 0.53350 -0.00370 0.00110  -0.00670 172 TYR A CZ  
2663 O OH  . TYR A 172 ? 0.46120 0.51730 0.46820 -0.01330 -0.00020 -0.00550 172 TYR A OH  
2674 N N   . LEU A 173 ? 0.36010 0.40770 0.39240 0.03300  0.00760  -0.01050 173 LEU A N   
2675 C CA  . LEU A 173 ? 0.37630 0.41490 0.40590 0.03600  0.00910  -0.01140 173 LEU A CA  
2676 C C   . LEU A 173 ? 0.40210 0.44230 0.43170 0.04220  0.01120  -0.01230 173 LEU A C   
2677 O O   . LEU A 173 ? 0.39860 0.43280 0.42440 0.04360  0.01340  -0.01420 173 LEU A O   
2678 C CB  . LEU A 173 ? 0.38880 0.42040 0.41650 0.03620  0.00800  -0.01010 173 LEU A CB  
2679 C CG  . LEU A 173 ? 0.38380 0.41330 0.41090 0.03200  0.00670  -0.00980 173 LEU A CG  
2680 C CD1 . LEU A 173 ? 0.48520 0.51070 0.51100 0.03240  0.00630  -0.00890 173 LEU A CD1 
2681 C CD2 . LEU A 173 ? 0.52460 0.55180 0.55040 0.02940  0.00720  -0.01090 173 LEU A CD2 
2693 N N   . PHE A 174 ? 0.37030 0.41880 0.40350 0.04640  0.01040  -0.01110 174 PHE A N   
2694 C CA  . PHE A 174 ? 0.36300 0.41410 0.39640 0.05460  0.01220  -0.01180 174 PHE A CA  
2695 C C   . PHE A 174 ? 0.39900 0.45890 0.43430 0.05540  0.01520  -0.01410 174 PHE A C   
2696 O O   . PHE A 174 ? 0.39960 0.45570 0.43180 0.06220  0.01800  -0.01600 174 PHE A O   
2697 C CB  . PHE A 174 ? 0.35420 0.41650 0.39240 0.05870  0.00980  -0.00950 174 PHE A CB  
2698 C CG  . PHE A 174 ? 0.38570 0.43820 0.42000 0.05960  0.00730  -0.00720 174 PHE A CG  
2699 C CD1 . PHE A 174 ? 0.40060 0.43560 0.42750 0.05860  0.00800  -0.00740 174 PHE A CD1 
2700 C CD2 . PHE A 174 ? 0.38950 0.45120 0.42690 0.06060  0.00430  -0.00480 174 PHE A CD2 
2701 C CE1 . PHE A 174 ? 0.45320 0.48020 0.47590 0.05850  0.00620  -0.00520 174 PHE A CE1 
2702 C CE2 . PHE A 174 ? 0.35320 0.40570 0.38580 0.06100  0.00210  -0.00270 174 PHE A CE2 
2703 C CZ  . PHE A 174 ? 0.42000 0.45520 0.44520 0.06010  0.00340  -0.00290 174 PHE A CZ  
2713 N N   . GLN A 175 ? 0.35790 0.42830 0.39680 0.04850  0.01490  -0.01400 175 GLN A N   
2714 C CA  . GLN A 175 ? 0.41120 0.49030 0.45090 0.04740  0.01800  -0.01600 175 GLN A CA  
2715 C C   . GLN A 175 ? 0.40670 0.47240 0.43910 0.04640  0.02030  -0.01840 175 GLN A C   
2716 O O   . GLN A 175 ? 0.40180 0.47170 0.43260 0.04770  0.02380  -0.02080 175 GLN A O   
2717 C CB  . GLN A 175 ? 0.45400 0.54210 0.49570 0.03790  0.01650  -0.01480 175 GLN A CB  
2718 C CG  . GLN A 175 ? 0.56840 0.67340 0.61660 0.03690  0.01490  -0.01300 175 GLN A CG  
2719 C CD  . GLN A 175 ? 0.78650 0.89940 0.83400 0.02720  0.01510  -0.01270 175 GLN A CD  
2720 O OE1 . GLN A 175 ? 0.89880 1.00550 0.94160 0.02390  0.01690  -0.01390 175 GLN A OE1 
2721 N NE2 . GLN A 175 ? 0.94860 1.07530 0.99960 0.02180  0.01310  -0.01100 175 GLN A NE2 
2730 N N   . HIS A 176 ? 0.35790 0.40920 0.38570 0.04320  0.01840  -0.01790 176 HIS A N   
2731 C CA  . HIS A 176 ? 0.41390 0.45260 0.43430 0.04120  0.01960  -0.01990 176 HIS A CA  
2732 C C   . HIS A 176 ? 0.38420 0.40870 0.39850 0.04630  0.02040  -0.02080 176 HIS A C   
2733 O O   . HIS A 176 ? 0.40380 0.41610 0.41140 0.04260  0.02020  -0.02170 176 HIS A O   
2734 C CB  . HIS A 176 ? 0.37370 0.40850 0.39330 0.03360  0.01670  -0.01840 176 HIS A CB  
2735 C CG  . HIS A 176 ? 0.47690 0.51950 0.49750 0.02810  0.01610  -0.01780 176 HIS A CG  
2736 N ND1 . HIS A 176 ? 0.50590 0.55650 0.53060 0.02560  0.01430  -0.01580 176 HIS A ND1 
2737 C CD2 . HIS A 176 ? 0.50140 0.54360 0.51760 0.02410  0.01710  -0.01890 176 HIS A CD2 
2738 C CE1 . HIS A 176 ? 0.46230 0.51570 0.48430 0.01990  0.01420  -0.01550 176 HIS A CE1 
2739 N NE2 . HIS A 176 ? 0.46650 0.51550 0.48380 0.01920  0.01580  -0.01720 176 HIS A NE2 
2747 N N   . ALA A 177 ? 0.48380 0.35490 0.36070 0.04710  -0.00330 0.00560  177 ALA A N   
2748 C CA  . ALA A 177 ? 0.45250 0.32300 0.33920 0.05000  -0.00340 0.00170  177 ALA A CA  
2749 C C   . ALA A 177 ? 0.50570 0.37670 0.39000 0.05230  0.00400  -0.00360 177 ALA A C   
2750 O O   . ALA A 177 ? 0.47760 0.35280 0.35640 0.05190  0.01020  -0.00350 177 ALA A O   
2751 C CB  . ALA A 177 ? 0.45090 0.32780 0.35480 0.05220  -0.00340 0.00540  177 ALA A CB  
2757 N N   . ASN A 178 ? 0.49780 0.36420 0.38700 0.05450  0.00360  -0.00840 178 ASN A N   
2758 C CA  . ASN A 178 ? 0.51470 0.38040 0.40340 0.05770  0.01070  -0.01420 178 ASN A CA  
2759 C C   . ASN A 178 ? 0.52490 0.39790 0.43080 0.06200  0.01500  -0.01110 178 ASN A C   
2760 O O   . ASN A 178 ? 0.52240 0.39290 0.43990 0.06430  0.01300  -0.01050 178 ASN A O   
2761 C CB  . ASN A 178 ? 0.61040 0.46600 0.49620 0.05800  0.00850  -0.02170 178 ASN A CB  
2762 C CG  . ASN A 178 ? 0.78130 0.63530 0.66910 0.06240  0.01650  -0.02830 178 ASN A CG  
2763 O OD1 . ASN A 178 ? 0.66730 0.52880 0.55570 0.06470  0.02390  -0.02760 178 ASN A OD1 
2764 N ND2 . ASN A 178 ? 0.98160 0.82610 0.87270 0.06370  0.01510  -0.03470 178 ASN A ND2 
2771 N N   . LEU A 179 ? 0.48990 0.37230 0.39750 0.06290  0.02080  -0.00870 179 LEU A N   
2772 C CA  . LEU A 179 ? 0.46010 0.35170 0.38330 0.06710  0.02450  -0.00540 179 LEU A CA  
2773 C C   . LEU A 179 ? 0.46420 0.36010 0.38920 0.07110  0.03280  -0.00950 179 LEU A C   
2774 O O   . LEU A 179 ? 0.48250 0.38940 0.41850 0.07390  0.03660  -0.00650 179 LEU A O   
2775 C CB  . LEU A 179 ? 0.46800 0.36920 0.39490 0.06460  0.02330  0.00090  179 LEU A CB  
2776 C CG  . LEU A 179 ? 0.49650 0.39490 0.42460 0.06190  0.01600  0.00470  179 LEU A CG  
2777 C CD1 . LEU A 179 ? 0.45700 0.36320 0.38620 0.05910  0.01550  0.00910  179 LEU A CD1 
2778 C CD2 . LEU A 179 ? 0.53030 0.42880 0.47100 0.06500  0.01350  0.00670  179 LEU A CD2 
2790 N N   . ASP A 180 ? 0.50720 0.39570 0.42160 0.07130  0.03580  -0.01670 180 ASP A N   
2791 C CA  . ASP A 180 ? 0.53190 0.42540 0.44750 0.07520  0.04480  -0.02150 180 ASP A CA  
2792 C C   . ASP A 180 ? 0.54310 0.43750 0.47590 0.08260  0.04760  -0.02240 180 ASP A C   
2793 O O   . ASP A 180 ? 0.60360 0.50530 0.54250 0.08710  0.05510  -0.02490 180 ASP A O   
2794 C CB  . ASP A 180 ? 0.56650 0.45160 0.46470 0.07360  0.04740  -0.02990 180 ASP A CB  
2795 C CG  . ASP A 180 ? 0.60850 0.49610 0.48960 0.06730  0.04740  -0.02790 180 ASP A CG  
2796 O OD1 . ASP A 180 ? 0.55710 0.45350 0.44170 0.06470  0.04740  -0.02080 180 ASP A OD1 
2797 O OD2 . ASP A 180 ? 0.64720 0.52750 0.51100 0.06470  0.04730  -0.03340 180 ASP A OD2 
2802 N N   . SER A 181 ? 0.51520 0.40270 0.45670 0.08400  0.04190  -0.01990 181 SER A N   
2803 C CA  . SER A 181 ? 0.53320 0.42140 0.49190 0.09090  0.04380  -0.01830 181 SER A CA  
2804 C C   . SER A 181 ? 0.53550 0.43810 0.50730 0.09270  0.04300  -0.00920 181 SER A C   
2805 O O   . SER A 181 ? 0.51480 0.42040 0.50130 0.09880  0.04430  -0.00610 181 SER A O   
2806 C CB  . SER A 181 ? 0.53840 0.41270 0.50130 0.09120  0.03860  -0.01890 181 SER A CB  
2807 O OG  . SER A 181 ? 0.67580 0.53660 0.62760 0.08950  0.03880  -0.02850 181 SER A OG  
2813 N N   . CYS A 182 ? 0.44680 0.35820 0.41380 0.08760  0.04080  -0.00490 182 CYS A N   
2814 C CA  . CYS A 182 ? 0.45010 0.37500 0.42800 0.08830  0.03910  0.00280  182 CYS A CA  
2815 C C   . CYS A 182 ? 0.48870 0.42850 0.47230 0.09030  0.04510  0.00280  182 CYS A C   
2816 O O   . CYS A 182 ? 0.47090 0.41330 0.44560 0.08690  0.04910  -0.00070 182 CYS A O   
2817 C CB  . CYS A 182 ? 0.45700 0.38360 0.42860 0.08190  0.03350  0.00670  182 CYS A CB  
2818 S SG  . CYS A 182 ? 0.47310 0.38660 0.44150 0.07940  0.02630  0.00780  182 CYS A SG  
2824 N N   . LYS A 183 ? 0.43290 0.38320 0.43180 0.09570  0.04560  0.00720  183 LYS A N   
2825 C CA  . LYS A 183 ? 0.44290 0.40940 0.45080 0.09830  0.05090  0.00750  183 LYS A CA  
2826 C C   . LYS A 183 ? 0.45050 0.43190 0.47020 0.09920  0.04680  0.01510  183 LYS A C   
2827 O O   . LYS A 183 ? 0.43690 0.41570 0.46200 0.10180  0.04190  0.02020  183 LYS A O   
2828 C CB  . LYS A 183 ? 0.45720 0.42250 0.47400 0.10660  0.05720  0.00330  183 LYS A CB  
2829 C CG  . LYS A 183 ? 0.53210 0.51640 0.56100 0.11000  0.06290  0.00360  183 LYS A CG  
2830 C CD  . LYS A 183 ? 0.58420 0.56670 0.61980 0.11780  0.07090  -0.00280 183 LYS A CD  
2831 C CE  . LYS A 183 ? 0.66770 0.65030 0.72120 0.12780  0.06980  0.00080  183 LYS A CE  
2832 N NZ  . LYS A 183 ? 0.72400 0.72090 0.79300 0.13540  0.07730  -0.00140 183 LYS A NZ  
2846 N N   . ARG A 184 ? 0.43560 0.43280 0.45870 0.09630  0.04870  0.01590  184 ARG A N   
2847 C CA  . ARG A 184 ? 0.40670 0.42030 0.44030 0.09630  0.04470  0.02190  184 ARG A CA  
2848 C C   . ARG A 184 ? 0.44790 0.47980 0.49360 0.09860  0.04970  0.02120  184 ARG A C   
2849 O O   . ARG A 184 ? 0.42730 0.46140 0.46870 0.09510  0.05550  0.01670  184 ARG A O   
2850 C CB  . ARG A 184 ? 0.40450 0.41920 0.42930 0.08780  0.04000  0.02320  184 ARG A CB  
2851 C CG  . ARG A 184 ? 0.43960 0.47330 0.47370 0.08610  0.03700  0.02700  184 ARG A CG  
2852 C CD  . ARG A 184 ? 0.41520 0.44670 0.44060 0.07880  0.03190  0.02750  184 ARG A CD  
2853 N NE  . ARG A 184 ? 0.40700 0.42900 0.42870 0.08070  0.02710  0.03050  184 ARG A NE  
2854 C CZ  . ARG A 184 ? 0.43170 0.44890 0.44570 0.07590  0.02290  0.03070  184 ARG A CZ  
2855 N NH1 . ARG A 184 ? 0.41160 0.43070 0.42060 0.06910  0.02240  0.02800  184 ARG A NH1 
2856 N NH2 . ARG A 184 ? 0.44060 0.45080 0.45290 0.07800  0.01960  0.03370  184 ARG A NH2 
2870 N N   . VAL A 185 ? 0.38520 0.43050 0.44640 0.10480  0.04760  0.02610  185 VAL A N   
2871 C CA  . VAL A 185 ? 0.44250 0.50900 0.51850 0.10720  0.05100  0.02650  185 VAL A CA  
2872 C C   . VAL A 185 ? 0.42130 0.50460 0.50360 0.10410  0.04400  0.03210  185 VAL A C   
2873 O O   . VAL A 185 ? 0.39760 0.48050 0.48170 0.10710  0.03770  0.03780  185 VAL A O   
2874 C CB  . VAL A 185 ? 0.45620 0.52560 0.54720 0.11850  0.05470  0.02700  185 VAL A CB  
2875 C CG1 . VAL A 185 ? 0.42410 0.51770 0.53200 0.12080  0.05850  0.02710  185 VAL A CG1 
2876 C CG2 . VAL A 185 ? 0.47430 0.52530 0.55720 0.12100  0.06160  0.01980  185 VAL A CG2 
2886 N N   . LEU A 186 ? 0.39780 0.49560 0.48260 0.09760  0.04530  0.03020  186 LEU A N   
2887 C CA  . LEU A 186 ? 0.43510 0.54990 0.52530 0.09300  0.03900  0.03340  186 LEU A CA  
2888 C C   . LEU A 186 ? 0.45830 0.59750 0.56750 0.09580  0.04100  0.03420  186 LEU A C   
2889 O O   . LEU A 186 ? 0.42440 0.56740 0.54000 0.09780  0.04880  0.03080  186 LEU A O   
2890 C CB  . LEU A 186 ? 0.42760 0.53810 0.50550 0.08140  0.03830  0.02980  186 LEU A CB  
2891 C CG  . LEU A 186 ? 0.44950 0.53820 0.50990 0.07810  0.03560  0.02900  186 LEU A CG  
2892 C CD1 . LEU A 186 ? 0.45980 0.54630 0.51130 0.06760  0.03400  0.02630  186 LEU A CD1 
2893 C CD2 . LEU A 186 ? 0.48360 0.57030 0.54400 0.08280  0.02900  0.03400  186 LEU A CD2 
2905 N N   . ASN A 187 ? 0.39880 0.55580 0.51730 0.09610  0.03390  0.03870  187 ASN A N   
2906 C CA  . ASN A 187 ? 0.44480 0.62820 0.58190 0.09680  0.03390  0.03960  187 ASN A CA  
2907 C C   . ASN A 187 ? 0.41710 0.61280 0.55220 0.08630  0.02790  0.03860  187 ASN A C   
2908 O O   . ASN A 187 ? 0.41170 0.60270 0.53700 0.08370  0.02080  0.04050  187 ASN A O   
2909 C CB  . ASN A 187 ? 0.43440 0.63030 0.58730 0.10830  0.03000  0.04640  187 ASN A CB  
2910 C CG  . ASN A 187 ? 0.48640 0.70700 0.66140 0.11220  0.03290  0.04650  187 ASN A CG  
2911 O OD1 . ASN A 187 ? 0.47850 0.70460 0.65740 0.10760  0.04020  0.04100  187 ASN A OD1 
2912 N ND2 . ASN A 187 ? 0.47900 0.71600 0.66950 0.12080  0.02710  0.05330  187 ASN A ND2 
2919 N N   . VAL A 188 ? 0.39860 0.60960 0.54290 0.07990  0.03130  0.03500  188 VAL A N   
2920 C CA  . VAL A 188 ? 0.40210 0.62610 0.54740 0.06930  0.02600  0.03310  188 VAL A CA  
2921 C C   . VAL A 188 ? 0.44500 0.69960 0.61300 0.07110  0.02390  0.03480  188 VAL A C   
2922 O O   . VAL A 188 ? 0.45050 0.71570 0.63170 0.07200  0.03130  0.03320  188 VAL A O   
2923 C CB  . VAL A 188 ? 0.45320 0.66660 0.58890 0.05780  0.03140  0.02740  188 VAL A CB  
2924 C CG1 . VAL A 188 ? 0.43650 0.66290 0.57530 0.04680  0.02570  0.02480  188 VAL A CG1 
2925 C CG2 . VAL A 188 ? 0.44210 0.62630 0.55620 0.05670  0.03250  0.02610  188 VAL A CG2 
2935 N N   . VAL A 189 ? 0.39950 0.66940 0.57190 0.07140  0.01390  0.03800  189 VAL A N   
2936 C CA  . VAL A 189 ? 0.43720 0.73740 0.63160 0.07510  0.00960  0.04120  189 VAL A CA  
2937 C C   . VAL A 189 ? 0.41090 0.72850 0.60830 0.06320  0.00300  0.03740  189 VAL A C   
2938 O O   . VAL A 189 ? 0.40780 0.72190 0.59280 0.05880  -0.00490 0.03690  189 VAL A O   
2939 C CB  . VAL A 189 ? 0.40690 0.71280 0.60530 0.08700  0.00230  0.04950  189 VAL A CB  
2940 C CG1 . VAL A 189 ? 0.43390 0.77240 0.65680 0.09160  -0.00230 0.05330  189 VAL A CG1 
2941 C CG2 . VAL A 189 ? 0.42650 0.71150 0.62080 0.09800  0.00830  0.05260  189 VAL A CG2 
2951 N N   . CYS A 190 ? 0.46900 0.80600 0.68350 0.05780  0.00640  0.03450  190 CYS A N   
2952 C CA  . CYS A 190 ? 0.44360 0.80130 0.66580 0.04670  -0.00030 0.03090  190 CYS A CA  
2953 C C   . CYS A 190 ? 0.50610 0.89780 0.75380 0.05240  -0.00520 0.03490  190 CYS A C   
2954 O O   . CYS A 190 ? 0.44190 0.84200 0.70540 0.06130  0.00110  0.03790  190 CYS A O   
2955 C CB  . CYS A 190 ? 0.44170 0.79520 0.66440 0.03360  0.00700  0.02420  190 CYS A CB  
2956 S SG  . CYS A 190 ? 0.39110 0.77540 0.63180 0.02080  0.00030  0.01980  190 CYS A SG  
2961 N N   . LYS A 191 ? 0.47050 0.88200 0.72220 0.04760  -0.01670 0.03460  191 LYS A N   
2962 C CA  . LYS A 191 ? 0.57460 1.02040 0.85060 0.05290  -0.02320 0.03900  191 LYS A CA  
2963 C C   . LYS A 191 ? 0.55120 1.01770 0.85100 0.04720  -0.01660 0.03540  191 LYS A C   
2964 O O   . LYS A 191 ? 0.55040 1.03820 0.87300 0.05630  -0.01500 0.03980  191 LYS A O   
2965 C CB  . LYS A 191 ? 0.47220 0.93460 0.74460 0.04770  -0.03760 0.03870  191 LYS A CB  
2968 N N   . THR A 192 ? 0.59400 1.05410 0.88930 0.03240  -0.01220 0.02780  192 THR A N   
2969 C CA  . THR A 192 ? 0.47900 0.95580 0.79510 0.02550  -0.00400 0.02460  192 THR A CA  
2970 C C   . THR A 192 ? 0.56730 1.03050 0.88450 0.03300  0.01060  0.02620  192 THR A C   
2971 O O   . THR A 192 ? 0.53800 1.02170 0.87790 0.03950  0.01620  0.02830  192 THR A O   
2972 C CB  . THR A 192 ? 0.56950 1.03910 0.87830 0.00700  -0.00340 0.01680  192 THR A CB  
2973 O OG1 . THR A 192 ? 0.63930 1.12680 0.95140 -0.00090 -0.01660 0.01360  192 THR A OG1 
2974 C CG2 . THR A 192 ? 0.50430 0.98500 0.83100 -0.00120 0.00780  0.01430  192 THR A CG2 
2982 N N   . CYS A 193 ? 0.43030 0.85950 0.72310 0.03250  0.01690  0.02480  193 CYS A N   
2983 C CA  . CYS A 193 ? 0.40840 0.82270 0.69800 0.03430  0.03130  0.02380  193 CYS A CA  
2984 C C   . CYS A 193 ? 0.37940 0.78310 0.66690 0.05080  0.03610  0.02790  193 CYS A C   
2985 O O   . CYS A 193 ? 0.45170 0.84750 0.73930 0.05370  0.04830  0.02650  193 CYS A O   
2986 C CB  . CYS A 193 ? 0.37710 0.76010 0.64130 0.02400  0.03540  0.01990  193 CYS A CB  
2987 S SG  . CYS A 193 ? 0.36510 0.75280 0.62940 0.00390  0.03130  0.01440  193 CYS A SG  
2992 N N   . GLY A 194 ? 0.40380 0.80590 0.68840 0.06130  0.02730  0.03270  194 GLY A N   
2993 C CA  . GLY A 194 ? 0.38920 0.78140 0.67420 0.07680  0.03130  0.03670  194 GLY A CA  
2994 C C   . GLY A 194 ? 0.40910 0.76560 0.66700 0.07890  0.03300  0.03640  194 GLY A C   
2995 O O   . GLY A 194 ? 0.44980 0.79090 0.68860 0.07100  0.02780  0.03500  194 GLY A O   
2999 N N   . GLN A 195 ? 0.49300 0.83660 0.75030 0.09010  0.04060  0.03730  195 GLN A N   
3000 C CA  . GLN A 195 ? 0.47860 0.79020 0.71340 0.09400  0.04200  0.03750  195 GLN A CA  
3001 C C   . GLN A 195 ? 0.50330 0.79620 0.72550 0.08920  0.05390  0.03160  195 GLN A C   
3002 O O   . GLN A 195 ? 0.50890 0.81250 0.74300 0.08990  0.06360  0.02870  195 GLN A O   
3003 C CB  . GLN A 195 ? 0.53870 0.84620 0.78050 0.10990  0.04130  0.04260  195 GLN A CB  
3004 C CG  . GLN A 195 ? 0.62180 0.94080 0.86980 0.11560  0.02880  0.05040  195 GLN A CG  
3005 C CD  . GLN A 195 ? 0.81720 1.12150 1.06470 0.12960  0.02800  0.05620  195 GLN A CD  
3006 O OE1 . GLN A 195 ? 0.74350 1.02860 0.98640 0.13490  0.03670  0.05310  195 GLN A OE1 
3007 N NE2 . GLN A 195 ? 0.76450 1.07760 1.01640 0.13530  0.01750  0.06460  195 GLN A NE2 
3016 N N   . GLN A 196 ? 0.44280 0.70880 0.64090 0.08440  0.05310  0.03000  196 GLN A N   
3017 C CA  . GLN A 196 ? 0.48200 0.72750 0.66470 0.08080  0.06290  0.02540  196 GLN A CA  
3018 C C   . GLN A 196 ? 0.45860 0.67600 0.62240 0.08610  0.06100  0.02610  196 GLN A C   
3019 O O   . GLN A 196 ? 0.46560 0.67180 0.61670 0.08230  0.05310  0.02780  196 GLN A O   
3020 C CB  . GLN A 196 ? 0.60150 0.84400 0.77430 0.06580  0.06390  0.02250  196 GLN A CB  
3021 C CG  . GLN A 196 ? 0.68620 0.90940 0.84280 0.06180  0.07380  0.01900  196 GLN A CG  
3022 C CD  . GLN A 196 ? 0.74320 0.97820 0.91160 0.06610  0.08550  0.01670  196 GLN A CD  
3023 O OE1 . GLN A 196 ? 0.72070 0.94120 0.87970 0.07210  0.09250  0.01430  196 GLN A OE1 
3024 N NE2 . GLN A 196 ? 0.86160 1.12360 1.05090 0.06300  0.08790  0.01690  196 GLN A NE2 
3033 N N   . GLN A 197 ? 0.45380 0.66060 0.61650 0.09480  0.06820  0.02420  197 GLN A N   
3034 C CA  . GLN A 197 ? 0.44300 0.62280 0.58860 0.09900  0.06700  0.02400  197 GLN A CA  
3035 C C   . GLN A 197 ? 0.49870 0.65920 0.62400 0.09150  0.07310  0.01900  197 GLN A C   
3036 O O   . GLN A 197 ? 0.49590 0.66120 0.62200 0.08850  0.08220  0.01520  197 GLN A O   
3037 C CB  . GLN A 197 ? 0.49250 0.66920 0.64790 0.11260  0.07070  0.02410  197 GLN A CB  
3038 C CG  . GLN A 197 ? 0.54750 0.69950 0.68970 0.11730  0.06660  0.02560  197 GLN A CG  
3039 C CD  . GLN A 197 ? 0.54330 0.68930 0.69520 0.13020  0.07060  0.02520  197 GLN A CD  
3040 O OE1 . GLN A 197 ? 0.57690 0.73030 0.74310 0.13880  0.06560  0.03120  197 GLN A OE1 
3041 N NE2 . GLN A 197 ? 0.55820 0.68980 0.70180 0.13180  0.07930  0.01800  197 GLN A NE2 
3050 N N   . THR A 198 ? 0.47350 0.61270 0.58060 0.08860  0.06810  0.01950  198 THR A N   
3051 C CA  . THR A 198 ? 0.47400 0.59350 0.56110 0.08260  0.07240  0.01560  198 THR A CA  
3052 C C   . THR A 198 ? 0.43050 0.52730 0.50520 0.08790  0.06970  0.01510  198 THR A C   
3053 O O   . THR A 198 ? 0.47690 0.57060 0.55460 0.09240  0.06270  0.01890  198 THR A O   
3054 C CB  . THR A 198 ? 0.48710 0.60360 0.56390 0.07070  0.06860  0.01630  198 THR A CB  
3055 O OG1 . THR A 198 ? 0.56310 0.67650 0.63820 0.07040  0.05870  0.01960  198 THR A OG1 
3056 C CG2 . THR A 198 ? 0.51280 0.65040 0.60190 0.06400  0.07170  0.01630  198 THR A CG2 
3064 N N   . THR A 199 ? 0.42970 0.51130 0.49060 0.08700  0.07560  0.01050  199 THR A N   
3065 C CA  . THR A 199 ? 0.41610 0.47600 0.46490 0.09100  0.07380  0.00870  199 THR A CA  
3066 C C   . THR A 199 ? 0.45780 0.50200 0.48610 0.08210  0.07200  0.00760  199 THR A C   
3067 O O   . THR A 199 ? 0.46980 0.51490 0.49000 0.07610  0.07740  0.00540  199 THR A O   
3068 C CB  . THR A 199 ? 0.48660 0.54210 0.53720 0.09860  0.08200  0.00310  199 THR A CB  
3069 O OG1 . THR A 199 ? 0.50480 0.57250 0.57590 0.10840  0.08240  0.00500  199 THR A OG1 
3070 C CG2 . THR A 199 ? 0.47870 0.51050 0.51470 0.10040  0.08010  -0.00010 199 THR A CG2 
3078 N N   . LEU A 200 ? 0.42390 0.45490 0.44460 0.08140  0.06430  0.00970  200 LEU A N   
3079 C CA  . LEU A 200 ? 0.42480 0.44060 0.42780 0.07430  0.06120  0.00920  200 LEU A CA  
3080 C C   . LEU A 200 ? 0.47860 0.47570 0.47160 0.07790  0.05980  0.00650  200 LEU A C   
3081 O O   . LEU A 200 ? 0.45740 0.45170 0.45800 0.08480  0.05800  0.00690  200 LEU A O   
3082 C CB  . LEU A 200 ? 0.42450 0.44210 0.42820 0.06960  0.05340  0.01350  200 LEU A CB  
3083 C CG  . LEU A 200 ? 0.48880 0.52410 0.50180 0.06460  0.05390  0.01530  200 LEU A CG  
3084 C CD1 . LEU A 200 ? 0.49460 0.53110 0.50840 0.06120  0.04610  0.01810  200 LEU A CD1 
3085 C CD2 . LEU A 200 ? 0.53790 0.57240 0.54300 0.05690  0.05930  0.01370  200 LEU A CD2 
3097 N N   . LYS A 201 ? 0.43320 0.41760 0.40930 0.07290  0.06010  0.00400  201 LYS A N   
3098 C CA  . LYS A 201 ? 0.45470 0.42210 0.42020 0.07510  0.05870  0.00030  201 LYS A CA  
3099 C C   . LYS A 201 ? 0.46260 0.41810 0.41470 0.06900  0.05210  0.00210  201 LYS A C   
3100 O O   . LYS A 201 ? 0.49060 0.44870 0.43770 0.06270  0.05120  0.00480  201 LYS A O   
3101 C CB  . LYS A 201 ? 0.51660 0.48110 0.47370 0.07640  0.06680  -0.00620 201 LYS A CB  
3102 C CG  . LYS A 201 ? 0.58170 0.55870 0.55350 0.08320  0.07430  -0.00860 201 LYS A CG  
3103 C CD  . LYS A 201 ? 0.87940 0.85210 0.84260 0.08560  0.08280  -0.01660 201 LYS A CD  
3104 C CE  . LYS A 201 ? 1.09280 1.07010 1.07180 0.09560  0.08800  -0.02050 201 LYS A CE  
3105 N NZ  . LYS A 201 ? 1.25220 1.22040 1.22120 0.09870  0.09510  -0.03010 201 LYS A NZ  
3119 N N   . GLY A 202 ? 0.47000 0.41250 0.41780 0.07090  0.04750  0.00060  202 GLY A N   
3120 C CA  . GLY A 202 ? 0.50680 0.43810 0.44220 0.06590  0.04140  0.00150  202 GLY A CA  
3121 C C   . GLY A 202 ? 0.48750 0.42300 0.42810 0.06290  0.03590  0.00700  202 GLY A C   
3122 O O   . GLY A 202 ? 0.45060 0.39240 0.40330 0.06590  0.03380  0.00970  202 GLY A O   
3126 N N   . VAL A 203 ? 0.46180 0.39370 0.39290 0.05710  0.03370  0.00870  203 VAL A N   
3127 C CA  . VAL A 203 ? 0.46730 0.40110 0.40260 0.05430  0.02840  0.01260  203 VAL A CA  
3128 C C   . VAL A 203 ? 0.44430 0.39270 0.39200 0.05440  0.03050  0.01460  203 VAL A C   
3129 O O   . VAL A 203 ? 0.42860 0.38130 0.38390 0.05520  0.02650  0.01660  203 VAL A O   
3130 C CB  . VAL A 203 ? 0.51870 0.44460 0.44240 0.04860  0.02590  0.01420  203 VAL A CB  
3131 C CG1 . VAL A 203 ? 0.64180 0.57200 0.56050 0.04450  0.03180  0.01480  203 VAL A CG1 
3132 C CG2 . VAL A 203 ? 0.44920 0.37560 0.37810 0.04670  0.02080  0.01700  203 VAL A CG2 
3142 N N   . GLU A 204 ? 0.44670 0.40420 0.39670 0.05340  0.03660  0.01380  204 GLU A N   
3143 C CA  . GLU A 204 ? 0.45360 0.42670 0.41660 0.05320  0.03770  0.01540  204 GLU A CA  
3144 C C   . GLU A 204 ? 0.41240 0.39320 0.38760 0.06010  0.03680  0.01610  204 GLU A C   
3145 O O   . GLU A 204 ? 0.43080 0.42460 0.41650 0.06050  0.03530  0.01820  204 GLU A O   
3146 C CB  . GLU A 204 ? 0.51240 0.49590 0.47790 0.05040  0.04470  0.01470  204 GLU A CB  
3147 C CG  . GLU A 204 ? 0.61660 0.59640 0.57350 0.04230  0.04600  0.01580  204 GLU A CG  
3148 C CD  . GLU A 204 ? 0.78860 0.75490 0.72920 0.04060  0.04800  0.01520  204 GLU A CD  
3149 O OE1 . GLU A 204 ? 0.71310 0.67500 0.64570 0.03410  0.04880  0.01740  204 GLU A OE1 
3150 O OE2 . GLU A 204 ? 0.68990 0.65000 0.62540 0.04550  0.04860  0.01240  204 GLU A OE2 
3157 N N   . ALA A 205 ? 0.36960 0.34250 0.34360 0.06550  0.03740  0.01470  205 ALA A N   
3158 C CA  . ALA A 205 ? 0.39190 0.36990 0.37760 0.07230  0.03650  0.01650  205 ALA A CA  
3159 C C   . ALA A 205 ? 0.39190 0.36770 0.37970 0.07260  0.02990  0.02020  205 ALA A C   
3160 O O   . ALA A 205 ? 0.40110 0.38430 0.39900 0.07710  0.02850  0.02360  205 ALA A O   
3161 C CB  . ALA A 205 ? 0.43120 0.39980 0.41600 0.07780  0.03970  0.01320  205 ALA A CB  
3167 N N   . VAL A 206 ? 0.38380 0.35050 0.36270 0.06810  0.02600  0.01990  206 VAL A N   
3168 C CA  . VAL A 206 ? 0.40990 0.37450 0.39060 0.06850  0.02080  0.02280  206 VAL A CA  
3169 C C   . VAL A 206 ? 0.41450 0.38480 0.39430 0.06390  0.01780  0.02370  206 VAL A C   
3170 O O   . VAL A 206 ? 0.41750 0.38800 0.39870 0.06410  0.01420  0.02560  206 VAL A O   
3171 C CB  . VAL A 206 ? 0.41590 0.36530 0.39010 0.06850  0.01840  0.02160  206 VAL A CB  
3172 C CG1 . VAL A 206 ? 0.41940 0.36220 0.39530 0.07300  0.02100  0.01970  206 VAL A CG1 
3173 C CG2 . VAL A 206 ? 0.44520 0.38600 0.40810 0.06350  0.01720  0.01900  206 VAL A CG2 
3183 N N   . MET A 207 ? 0.38720 0.36210 0.36510 0.05960  0.01960  0.02210  207 MET A N   
3184 C CA  . MET A 207 ? 0.40600 0.38390 0.38290 0.05460  0.01690  0.02160  207 MET A CA  
3185 C C   . MET A 207 ? 0.40410 0.39830 0.38910 0.05320  0.01810  0.02170  207 MET A C   
3186 O O   . MET A 207 ? 0.42960 0.43030 0.41830 0.05360  0.02210  0.02140  207 MET A O   
3187 C CB  . MET A 207 ? 0.41330 0.38000 0.38080 0.04970  0.01730  0.01990  207 MET A CB  
3188 C CG  . MET A 207 ? 0.44570 0.39820 0.40610 0.05040  0.01390  0.01990  207 MET A CG  
3189 S SD  . MET A 207 ? 0.50170 0.44190 0.45180 0.04510  0.01270  0.01950  207 MET A SD  
3190 C CE  . MET A 207 ? 0.43660 0.37920 0.39170 0.04290  0.00900  0.01890  207 MET A CE  
3200 N N   . TYR A 208 ? 0.36280 0.36470 0.35090 0.05170  0.01470  0.02180  208 TYR A N   
3201 C CA  . TYR A 208 ? 0.40840 0.42600 0.40340 0.04890  0.01460  0.02100  208 TYR A CA  
3202 C C   . TYR A 208 ? 0.40170 0.41920 0.39420 0.04380  0.01130  0.01800  208 TYR A C   
3203 O O   . TYR A 208 ? 0.38230 0.39560 0.37160 0.04520  0.00840  0.01800  208 TYR A O   
3204 C CB  . TYR A 208 ? 0.39060 0.42360 0.39460 0.05400  0.01340  0.02420  208 TYR A CB  
3205 C CG  . TYR A 208 ? 0.39870 0.44950 0.41030 0.05050  0.01250  0.02290  208 TYR A CG  
3206 C CD1 . TYR A 208 ? 0.41440 0.47210 0.43190 0.04840  0.01630  0.02190  208 TYR A CD1 
3207 C CD2 . TYR A 208 ? 0.40410 0.46520 0.41670 0.04860  0.00790  0.02220  208 TYR A CD2 
3208 C CE1 . TYR A 208 ? 0.42040 0.49520 0.44630 0.04430  0.01520  0.02050  208 TYR A CE1 
3209 C CE2 . TYR A 208 ? 0.38500 0.46290 0.40460 0.04450  0.00630  0.02020  208 TYR A CE2 
3210 C CZ  . TYR A 208 ? 0.43520 0.51990 0.46220 0.04230  0.00980  0.01950  208 TYR A CZ  
3211 O OH  . TYR A 208 ? 0.41890 0.52120 0.45440 0.03750  0.00790  0.01730  208 TYR A OH  
3221 N N   . MET A 209 ? 0.37590 0.39840 0.37080 0.03770  0.01200  0.01520  209 MET A N   
3222 C CA  . MET A 209 ? 0.37030 0.39210 0.36380 0.03220  0.00930  0.01110  209 MET A CA  
3223 C C   . MET A 209 ? 0.40070 0.44160 0.40200 0.02970  0.00740  0.00920  209 MET A C   
3224 O O   . MET A 209 ? 0.38660 0.43690 0.39450 0.02690  0.00940  0.00930  209 MET A O   
3225 C CB  . MET A 209 ? 0.41450 0.42360 0.40420 0.02610  0.01130  0.00920  209 MET A CB  
3226 C CG  . MET A 209 ? 0.52680 0.53660 0.51830 0.01920  0.00930  0.00430  209 MET A CG  
3227 S SD  . MET A 209 ? 0.50640 0.50940 0.49370 0.02070  0.00520  0.00020  209 MET A SD  
3228 C CE  . MET A 209 ? 0.55050 0.53670 0.53070 0.02640  0.00560  0.00430  209 MET A CE  
3238 N N   . GLY A 210 ? 0.38490 0.43260 0.38540 0.03060  0.00340  0.00750  210 GLY A N   
3239 C CA  . GLY A 210 ? 0.39670 0.46220 0.40270 0.02720  0.00040  0.00460  210 GLY A CA  
3240 C C   . GLY A 210 ? 0.37960 0.45640 0.38400 0.03150  -0.00340 0.00610  210 GLY A C   
3241 O O   . GLY A 210 ? 0.40600 0.49510 0.41090 0.02810  -0.00690 0.00210  210 GLY A O   
3245 N N   . THR A 211 ? 0.33440 0.40740 0.33660 0.03860  -0.00270 0.01190  211 THR A N   
3246 C CA  . THR A 211 ? 0.37970 0.46090 0.37870 0.04240  -0.00560 0.01450  211 THR A CA  
3247 C C   . THR A 211 ? 0.35410 0.42140 0.34830 0.04720  -0.00380 0.01840  211 THR A C   
3248 O O   . THR A 211 ? 0.37010 0.42540 0.36520 0.04950  -0.00100 0.02080  211 THR A O   
3249 C CB  . THR A 211 ? 0.39230 0.49210 0.39770 0.04650  -0.00800 0.02040  211 THR A CB  
3250 O OG1 . THR A 211 ? 0.40330 0.51050 0.40380 0.04970  -0.01090 0.02390  211 THR A OG1 
3251 C CG2 . THR A 211 ? 0.40140 0.49710 0.41270 0.05240  -0.00510 0.02680  211 THR A CG2 
3259 N N   . LEU A 212 ? 0.37380 0.44390 0.36290 0.04850  -0.00530 0.01870  212 LEU A N   
3260 C CA  . LEU A 212 ? 0.37040 0.43020 0.35640 0.05250  -0.00380 0.02260  212 LEU A CA  
3261 C C   . LEU A 212 ? 0.38410 0.45000 0.37300 0.05830  -0.00410 0.03170  212 LEU A C   
3262 O O   . LEU A 212 ? 0.38460 0.44080 0.37310 0.06140  -0.00250 0.03580  212 LEU A O   
3263 C CB  . LEU A 212 ? 0.35920 0.41930 0.33890 0.05100  -0.00420 0.01870  212 LEU A CB  
3264 C CG  . LEU A 212 ? 0.35210 0.40390 0.32920 0.04620  -0.00380 0.00950  212 LEU A CG  
3265 C CD1 . LEU A 212 ? 0.37420 0.42820 0.34620 0.04630  -0.00340 0.00600  212 LEU A CD1 
3266 C CD2 . LEU A 212 ? 0.38380 0.41740 0.36230 0.04620  -0.00190 0.00940  212 LEU A CD2 
3278 N N   . SER A 213 ? 0.39100 0.47320 0.38340 0.05960  -0.00660 0.03500  213 SER A N   
3279 C CA  . SER A 213 ? 0.36230 0.45170 0.35730 0.06540  -0.00760 0.04460  213 SER A CA  
3280 C C   . SER A 213 ? 0.38310 0.46850 0.38700 0.06990  -0.00610 0.04900  213 SER A C   
3281 O O   . SER A 213 ? 0.38840 0.48270 0.39860 0.06960  -0.00680 0.04770  213 SER A O   
3282 C CB  . SER A 213 ? 0.39150 0.50170 0.38520 0.06510  -0.01190 0.04670  213 SER A CB  
3283 O OG  . SER A 213 ? 0.41130 0.52870 0.40940 0.07130  -0.01340 0.05740  213 SER A OG  
3289 N N   . TYR A 214 ? 0.40630 0.47880 0.41140 0.07390  -0.00380 0.05380  214 TYR A N   
3290 C CA  . TYR A 214 ? 0.41130 0.47950 0.42480 0.07910  -0.00200 0.05770  214 TYR A CA  
3291 C C   . TYR A 214 ? 0.42950 0.51390 0.45030 0.08410  -0.00480 0.06520  214 TYR A C   
3292 O O   . TYR A 214 ? 0.39130 0.48060 0.42090 0.08720  -0.00410 0.06570  214 TYR A O   
3293 C CB  . TYR A 214 ? 0.40320 0.45400 0.41610 0.08170  0.00040  0.06070  214 TYR A CB  
3294 C CG  . TYR A 214 ? 0.37790 0.41840 0.39720 0.08590  0.00320  0.06100  214 TYR A CG  
3295 C CD1 . TYR A 214 ? 0.38470 0.42610 0.40680 0.08520  0.00530  0.05570  214 TYR A CD1 
3296 C CD2 . TYR A 214 ? 0.39620 0.42560 0.41880 0.09010  0.00430  0.06630  214 TYR A CD2 
3297 C CE1 . TYR A 214 ? 0.40010 0.43230 0.42720 0.08920  0.00880  0.05500  214 TYR A CE1 
3298 C CE2 . TYR A 214 ? 0.44600 0.46510 0.47420 0.09390  0.00720  0.06530  214 TYR A CE2 
3299 C CZ  . TYR A 214 ? 0.44030 0.46100 0.47010 0.09370  0.00960  0.05920  214 TYR A CZ  
3300 O OH  . TYR A 214 ? 0.43550 0.44630 0.47010 0.09790  0.01310  0.05730  214 TYR A OH  
3310 N N   . GLU A 215 ? 0.39190 0.48580 0.40910 0.08500  -0.00790 0.07130  215 GLU A N   
3311 C CA  . GLU A 215 ? 0.43210 0.54220 0.45560 0.09000  -0.01160 0.07970  215 GLU A CA  
3312 C C   . GLU A 215 ? 0.41510 0.54280 0.44300 0.08780  -0.01440 0.07520  215 GLU A C   
3313 O O   . GLU A 215 ? 0.41310 0.55090 0.45190 0.09260  -0.01590 0.07950  215 GLU A O   
3314 C CB  . GLU A 215 ? 0.46710 0.58520 0.48330 0.09040  -0.01450 0.08720  215 GLU A CB  
3315 C CG  . GLU A 215 ? 0.65510 0.75910 0.67140 0.09410  -0.01200 0.09570  215 GLU A CG  
3316 C CD  . GLU A 215 ? 0.79280 0.88880 0.82140 0.10130  -0.01080 0.10190  215 GLU A CD  
3317 O OE1 . GLU A 215 ? 0.59750 0.70640 0.63380 0.10630  -0.01390 0.10790  215 GLU A OE1 
3318 O OE2 . GLU A 215 ? 0.87220 0.94920 0.90320 0.10200  -0.00680 0.10010  215 GLU A OE2 
3325 N N   . GLN A 216 ? 0.40490 0.53640 0.42610 0.08040  -0.01520 0.06620  216 GLN A N   
3326 C CA  . GLN A 216 ? 0.41440 0.56220 0.44070 0.07700  -0.01800 0.06130  216 GLN A CA  
3327 C C   . GLN A 216 ? 0.39630 0.53930 0.43280 0.07770  -0.01410 0.05800  216 GLN A C   
3328 O O   . GLN A 216 ? 0.41740 0.57580 0.46440 0.07880  -0.01580 0.05860  216 GLN A O   
3329 C CB  . GLN A 216 ? 0.45340 0.60370 0.47040 0.06850  -0.01940 0.05180  216 GLN A CB  
3330 C CG  . GLN A 216 ? 0.59830 0.76870 0.62010 0.06420  -0.02380 0.04750  216 GLN A CG  
3331 C CD  . GLN A 216 ? 0.65810 0.84990 0.68260 0.06840  -0.03000 0.05550  216 GLN A CD  
3332 O OE1 . GLN A 216 ? 0.60060 0.79590 0.61560 0.06970  -0.03240 0.05980  216 GLN A OE1 
3333 N NE2 . GLN A 216 ? 0.58570 0.79240 0.62340 0.07080  -0.03240 0.05810  216 GLN A NE2 
3342 N N   . PHE A 217 ? 0.39540 0.51830 0.42890 0.07690  -0.00890 0.05440  217 PHE A N   
3343 C CA  . PHE A 217 ? 0.40800 0.52530 0.44890 0.07780  -0.00430 0.05150  217 PHE A CA  
3344 C C   . PHE A 217 ? 0.40850 0.53190 0.46160 0.08650  -0.00370 0.05850  217 PHE A C   
3345 O O   . PHE A 217 ? 0.37200 0.50280 0.43530 0.08770  -0.00130 0.05680  217 PHE A O   
3346 C CB  . PHE A 217 ? 0.37600 0.47030 0.40890 0.07600  0.00020  0.04770  217 PHE A CB  
3347 C CG  . PHE A 217 ? 0.36630 0.45330 0.40160 0.07420  0.00530  0.04260  217 PHE A CG  
3348 C CD1 . PHE A 217 ? 0.38510 0.48070 0.42290 0.06820  0.00600  0.03750  217 PHE A CD1 
3349 C CD2 . PHE A 217 ? 0.41060 0.48140 0.44440 0.07760  0.00940  0.04270  217 PHE A CD2 
3350 C CE1 . PHE A 217 ? 0.42700 0.51590 0.46570 0.06600  0.01130  0.03380  217 PHE A CE1 
3351 C CE2 . PHE A 217 ? 0.39840 0.46260 0.43180 0.07570  0.01430  0.03810  217 PHE A CE2 
3352 C CZ  . PHE A 217 ? 0.38110 0.45470 0.41680 0.07000  0.01550  0.03410  217 PHE A CZ  
3362 N N   . LYS A 218 ? 0.40320 0.52390 0.45640 0.09260  -0.00550 0.06670  218 LYS A N   
3363 C CA  . LYS A 218 ? 0.38990 0.51470 0.45560 0.10170  -0.00520 0.07410  218 LYS A CA  
3364 C C   . LYS A 218 ? 0.42170 0.57160 0.49690 0.10410  -0.01060 0.07860  218 LYS A C   
3365 O O   . LYS A 218 ? 0.41280 0.57100 0.50230 0.11050  -0.00980 0.08160  218 LYS A O   
3366 C CB  . LYS A 218 ? 0.40590 0.51840 0.46880 0.10680  -0.00570 0.08220  218 LYS A CB  
3367 C CG  . LYS A 218 ? 0.41630 0.50470 0.47430 0.10640  -0.00060 0.07870  218 LYS A CG  
3368 C CD  . LYS A 218 ? 0.44140 0.51940 0.49640 0.10930  -0.00160 0.08660  218 LYS A CD  
3369 C CE  . LYS A 218 ? 0.51790 0.57250 0.56950 0.10860  0.00270  0.08290  218 LYS A CE  
3370 N NZ  . LYS A 218 ? 0.50870 0.55400 0.55840 0.11000  0.00170  0.09080  218 LYS A NZ  
3384 N N   . LYS A 219 ? 0.43450 0.59730 0.50240 0.09940  -0.01620 0.07920  219 LYS A N   
3385 C CA  . LYS A 219 ? 0.44740 0.63580 0.52320 0.10070  -0.02260 0.08300  219 LYS A CA  
3386 C C   . LYS A 219 ? 0.43480 0.63600 0.51850 0.09540  -0.02200 0.07470  219 LYS A C   
3387 O O   . LYS A 219 ? 0.48120 0.70170 0.57920 0.09890  -0.02480 0.07760  219 LYS A O   
3388 C CB  . LYS A 219 ? 0.46640 0.66450 0.52970 0.09680  -0.02880 0.08540  219 LYS A CB  
3389 C CG  . LYS A 219 ? 0.60750 0.79730 0.66400 0.10200  -0.02960 0.09580  219 LYS A CG  
3390 C CD  . LYS A 219 ? 0.73940 0.94090 0.78210 0.09810  -0.03510 0.09810  219 LYS A CD  
3391 C CE  . LYS A 219 ? 1.17840 1.40370 1.22570 0.10270  -0.04290 0.10800  219 LYS A CE  
3392 N NZ  . LYS A 219 ? 1.08510 1.32740 1.11880 0.09660  -0.04880 0.10580  219 LYS A NZ  
3406 N N   . GLY A 220 ? 0.42100 0.61190 0.49690 0.08700  -0.01850 0.06500  220 GLY A N   
3407 C CA  . GLY A 220 ? 0.43690 0.63850 0.51930 0.08030  -0.01760 0.05730  220 GLY A CA  
3408 C C   . GLY A 220 ? 0.43780 0.63820 0.50850 0.06990  -0.01970 0.04920  220 GLY A C   
3409 O O   . GLY A 220 ? 0.42400 0.63060 0.48610 0.06820  -0.02520 0.05010  220 GLY A O   
3413 N N   . VAL A 221 ? 0.40460 0.59590 0.47440 0.06300  -0.01510 0.04130  221 VAL A N   
3414 C CA  . VAL A 221 ? 0.44150 0.63080 0.50300 0.05290  -0.01670 0.03290  221 VAL A CA  
3415 C C   . VAL A 221 ? 0.46900 0.67240 0.54190 0.04620  -0.01650 0.02780  221 VAL A C   
3416 O O   . VAL A 221 ? 0.40670 0.61210 0.49050 0.04800  -0.01170 0.02890  221 VAL A O   
3417 C CB  . VAL A 221 ? 0.45910 0.62260 0.50850 0.04970  -0.01170 0.02860  221 VAL A CB  
3418 C CG1 . VAL A 221 ? 0.48520 0.63720 0.52450 0.05510  -0.01240 0.03300  221 VAL A CG1 
3419 C CG2 . VAL A 221 ? 0.42040 0.57220 0.47430 0.05050  -0.00460 0.02810  221 VAL A CG2 
3429 N N   . GLN A 222 ? 0.47670 0.69000 0.54730 0.03800  -0.02140 0.02170  222 GLN A N   
3430 C CA  . GLN A 222 ? 0.46310 0.69050 0.54500 0.02980  -0.02200 0.01630  222 GLN A CA  
3431 C C   . GLN A 222 ? 0.45080 0.65930 0.52850 0.02180  -0.01600 0.00980  222 GLN A C   
3432 O O   . GLN A 222 ? 0.42930 0.62030 0.49390 0.01860  -0.01580 0.00560  222 GLN A O   
3433 C CB  . GLN A 222 ? 0.50190 0.74830 0.58320 0.02410  -0.03070 0.01200  222 GLN A CB  
3434 C CG  . GLN A 222 ? 0.51130 0.77280 0.59170 0.03230  -0.03700 0.01950  222 GLN A CG  
3435 C CD  . GLN A 222 ? 0.52480 0.80150 0.62200 0.04020  -0.03670 0.02770  222 GLN A CD  
3436 O OE1 . GLN A 222 ? 0.55060 0.82250 0.64770 0.05050  -0.03540 0.03630  222 GLN A OE1 
3437 N NE2 . GLN A 222 ? 0.53910 0.83400 0.65220 0.03550  -0.03760 0.02480  222 GLN A NE2 
3446 N N   . ILE A 223 ? 0.42620 0.63850 0.51540 0.01900  -0.01100 0.00950  223 ILE A N   
3447 C CA  . ILE A 223 ? 0.40360 0.60000 0.49010 0.01080  -0.00510 0.00480  223 ILE A CA  
3448 C C   . ILE A 223 ? 0.41650 0.63100 0.51870 0.00260  -0.00450 0.00190  223 ILE A C   
3449 O O   . ILE A 223 ? 0.45660 0.69480 0.57320 0.00540  -0.00680 0.00460  223 ILE A O   
3450 C CB  . ILE A 223 ? 0.48110 0.65890 0.56290 0.01610  0.00300  0.00870  223 ILE A CB  
3451 C CG1 . ILE A 223 ? 0.42350 0.61540 0.51870 0.02310  0.00670  0.01380  223 ILE A CG1 
3452 C CG2 . ILE A 223 ? 0.47250 0.63180 0.53970 0.02280  0.00210  0.01100  223 ILE A CG2 
3453 C CD1 . ILE A 223 ? 0.43130 0.60690 0.52240 0.02680  0.01540  0.01590  223 ILE A CD1 
3465 N N   . PRO A 224 ? 0.47900 0.68280 0.57980 -0.00780 -0.00130 -0.00310 224 PRO A N   
3466 C CA  . PRO A 224 ? 0.50930 0.72940 0.62580 -0.01690 0.00030  -0.00560 224 PRO A CA  
3467 C C   . PRO A 224 ? 0.47280 0.70320 0.60160 -0.01220 0.00740  -0.00010 224 PRO A C   
3468 O O   . PRO A 224 ? 0.45270 0.66810 0.57440 -0.00590 0.01400  0.00380  224 PRO A O   
3469 C CB  . PRO A 224 ? 0.50570 0.70500 0.61530 -0.02770 0.00380  -0.01030 224 PRO A CB  
3470 C CG  . PRO A 224 ? 0.55420 0.73300 0.64630 -0.02510 0.00040  -0.01270 224 PRO A CG  
3471 C CD  . PRO A 224 ? 0.54830 0.72500 0.63400 -0.01190 0.00080  -0.00640 224 PRO A CD  
3479 N N   . CYS A 225 ? 0.39900 0.65600 0.54670 -0.01530 0.00600  -0.00040 225 CYS A N   
3480 C CA  . CYS A 225 ? 0.35980 0.62890 0.52230 -0.01380 0.01410  0.00300  225 CYS A CA  
3481 C C   . CYS A 225 ? 0.42710 0.69920 0.59800 -0.02790 0.01840  -0.00070 225 CYS A C   
3482 O O   . CYS A 225 ? 0.40910 0.68430 0.58180 -0.03830 0.01270  -0.00610 225 CYS A O   
3483 C CB  . CYS A 225 ? 0.36560 0.66490 0.54690 -0.00630 0.01030  0.00630  225 CYS A CB  
3484 S SG  . CYS A 225 ? 0.34000 0.65280 0.53930 -0.00130 0.02200  0.01030  225 CYS A SG  
3489 N N   . THR A 226 ? 0.38190 0.65290 0.55790 -0.02850 0.02890  0.00210  226 THR A N   
3490 C CA  . THR A 226 ? 0.40980 0.68450 0.59480 -0.04220 0.03410  0.00010  226 THR A CA  
3491 C C   . THR A 226 ? 0.47930 0.78530 0.68730 -0.04930 0.02890  -0.00290 226 THR A C   
3492 O O   . THR A 226 ? 0.50090 0.80920 0.71600 -0.06320 0.02970  -0.00630 226 THR A O   
3493 C CB  . THR A 226 ? 0.46650 0.73830 0.65310 -0.04090 0.04700  0.00420  226 THR A CB  
3494 O OG1 . THR A 226 ? 0.61150 0.88970 0.80870 -0.05500 0.05220  0.00320  226 THR A OG1 
3495 C CG2 . THR A 226 ? 0.43390 0.72760 0.63490 -0.02920 0.05050  0.00740  226 THR A CG2 
3503 N N   . CYS A 227 ? 0.43530 0.76550 0.65560 -0.04040 0.02310  -0.00140 227 CYS A N   
3504 C CA  . CYS A 227 ? 0.35850 0.72080 0.60130 -0.04670 0.01680  -0.00400 227 CYS A CA  
3505 C C   . CYS A 227 ? 0.38760 0.74960 0.62470 -0.05480 0.00500  -0.01040 227 CYS A C   
3506 O O   . CYS A 227 ? 0.38210 0.76980 0.63640 -0.06200 -0.00170 -0.01400 227 CYS A O   
3507 C CB  . CYS A 227 ? 0.36040 0.74910 0.61870 -0.03360 0.01380  0.00060  227 CYS A CB  
3508 S SG  . CYS A 227 ? 0.33740 0.72330 0.58220 -0.02060 0.00170  0.00290  227 CYS A SG  
3513 N N   . GLY A 228 ? 0.40860 0.74340 0.62280 -0.05370 0.00220  -0.01260 228 GLY A N   
3514 C CA  . GLY A 228 ? 0.40910 0.74100 0.61550 -0.06050 -0.00780 -0.01970 228 GLY A CA  
3515 C C   . GLY A 228 ? 0.33310 0.67280 0.53170 -0.05020 -0.01750 -0.01870 228 GLY A C   
3516 O O   . GLY A 228 ? 0.33780 0.66880 0.52330 -0.05340 -0.02440 -0.02440 228 GLY A O   
3520 N N   . LYS A 229 ? 0.32560 0.68130 0.53200 -0.03770 -0.01770 -0.01150 229 LYS A N   
3521 C CA  . LYS A 229 ? 0.32240 0.68330 0.52030 -0.02680 -0.02600 -0.00820 229 LYS A CA  
3522 C C   . LYS A 229 ? 0.40710 0.73740 0.58300 -0.01860 -0.02180 -0.00530 229 LYS A C   
3523 O O   . LYS A 229 ? 0.37890 0.68590 0.54700 -0.02060 -0.01310 -0.00560 229 LYS A O   
3524 C CB  . LYS A 229 ? 0.33380 0.72230 0.55030 -0.01650 -0.02770 -0.00080 229 LYS A CB  
3525 C CG  . LYS A 229 ? 0.32020 0.74300 0.55870 -0.02400 -0.03480 -0.00380 229 LYS A CG  
3526 C CD  . LYS A 229 ? 0.36090 0.81180 0.62100 -0.01310 -0.03580 0.00400  229 LYS A CD  
3527 C CE  . LYS A 229 ? 0.45280 0.92320 0.71280 -0.00570 -0.04880 0.00780  229 LYS A CE  
3528 N NZ  . LYS A 229 ? 0.49320 0.96800 0.74260 -0.01620 -0.05970 0.00010  229 LYS A NZ  
3542 N N   . GLN A 230 ? 0.37490 0.70570 0.54050 -0.00970 -0.02820 -0.00200 230 GLN A N   
3543 C CA  . GLN A 230 ? 0.38780 0.69360 0.53600 -0.00050 -0.02450 0.00220  230 GLN A CA  
3544 C C   . GLN A 230 ? 0.37900 0.68960 0.53560 0.01240  -0.02020 0.01110  230 GLN A C   
3545 O O   . GLN A 230 ? 0.41250 0.74660 0.58210 0.01870  -0.02530 0.01590  230 GLN A O   
3546 C CB  . GLN A 230 ? 0.45580 0.75890 0.58830 0.00250  -0.03260 0.00170  230 GLN A CB  
3547 C CG  . GLN A 230 ? 0.46540 0.77080 0.59100 -0.00870 -0.03910 -0.00790 230 GLN A CG  
3548 C CD  . GLN A 230 ? 0.59540 0.87560 0.71230 -0.01790 -0.03360 -0.01540 230 GLN A CD  
3549 O OE1 . GLN A 230 ? 0.65110 0.93440 0.77110 -0.02950 -0.03610 -0.02390 230 GLN A OE1 
3550 N NE2 . GLN A 230 ? 0.61230 0.86710 0.71850 -0.01280 -0.02650 -0.01220 230 GLN A NE2 
3559 N N   . ALA A 231 ? 0.45420 0.74240 0.60360 0.01660  -0.01140 0.01330  231 ALA A N   
3560 C CA  . ALA A 231 ? 0.44740 0.73440 0.60080 0.02960  -0.00750 0.02060  231 ALA A CA  
3561 C C   . ALA A 231 ? 0.41620 0.68600 0.55290 0.03740  -0.01030 0.02440  231 ALA A C   
3562 O O   . ALA A 231 ? 0.41010 0.66540 0.53100 0.03260  -0.01290 0.02080  231 ALA A O   
3563 C CB  . ALA A 231 ? 0.41120 0.68520 0.56640 0.03010  0.00390  0.02040  231 ALA A CB  
3569 N N   . THR A 232 ? 0.41680 0.68820 0.55820 0.04940  -0.00950 0.03160  232 THR A N   
3570 C CA  . THR A 232 ? 0.39720 0.65190 0.52500 0.05710  -0.01100 0.03630  232 THR A CA  
3571 C C   . THR A 232 ? 0.37700 0.61000 0.50090 0.06250  -0.00200 0.03730  232 THR A C   
3572 O O   . THR A 232 ? 0.34940 0.58840 0.48620 0.06840  0.00310  0.03940  232 THR A O   
3573 C CB  . THR A 232 ? 0.44220 0.71400 0.57760 0.06660  -0.01790 0.04460  232 THR A CB  
3574 O OG1 . THR A 232 ? 0.45860 0.75160 0.59570 0.06090  -0.02700 0.04310  232 THR A OG1 
3575 C CG2 . THR A 232 ? 0.40280 0.65650 0.52460 0.07370  -0.01870 0.05020  232 THR A CG2 
3583 N N   . LYS A 233 ? 0.37380 0.58260 0.48040 0.06030  0.00000  0.03520  233 LYS A N   
3584 C CA  . LYS A 233 ? 0.38000 0.56680 0.48000 0.06490  0.00710  0.03580  233 LYS A CA  
3585 C C   . LYS A 233 ? 0.37790 0.55470 0.47130 0.07320  0.00420  0.04170  233 LYS A C   
3586 O O   . LYS A 233 ? 0.42100 0.59430 0.50420 0.07100  -0.00090 0.04230  233 LYS A O   
3587 C CB  . LYS A 233 ? 0.40910 0.57600 0.49520 0.05650  0.01070  0.03000  233 LYS A CB  
3588 C CG  . LYS A 233 ? 0.43420 0.57790 0.51070 0.06050  0.01660  0.03020  233 LYS A CG  
3589 C CD  . LYS A 233 ? 0.39870 0.52530 0.46280 0.05200  0.01960  0.02530  233 LYS A CD  
3590 C CE  . LYS A 233 ? 0.46440 0.59550 0.53420 0.04690  0.02610  0.02250  233 LYS A CE  
3591 N NZ  . LYS A 233 ? 0.46270 0.57540 0.51940 0.03910  0.02880  0.01930  233 LYS A NZ  
3605 N N   . TYR A 234 ? 0.41140 0.58380 0.51120 0.08260  0.00780  0.04580  234 TYR A N   
3606 C CA  . TYR A 234 ? 0.40620 0.56660 0.50050 0.08980  0.00570  0.05170  234 TYR A CA  
3607 C C   . TYR A 234 ? 0.41500 0.55590 0.50770 0.09510  0.01260  0.05100  234 TYR A C   
3608 O O   . TYR A 234 ? 0.42920 0.57010 0.52790 0.09590  0.01900  0.04720  234 TYR A O   
3609 C CB  . TYR A 234 ? 0.41990 0.59810 0.52530 0.09740  -0.00020 0.06010  234 TYR A CB  
3610 C CG  . TYR A 234 ? 0.43490 0.62560 0.55920 0.10560  0.00240  0.06290  234 TYR A CG  
3611 C CD1 . TYR A 234 ? 0.46060 0.63930 0.59000 0.11550  0.00630  0.06670  234 TYR A CD1 
3612 C CD2 . TYR A 234 ? 0.41660 0.63170 0.55490 0.10360  0.00100  0.06150  234 TYR A CD2 
3613 C CE1 . TYR A 234 ? 0.46630 0.65620 0.61420 0.12390  0.00910  0.06880  234 TYR A CE1 
3614 C CE2 . TYR A 234 ? 0.42290 0.65110 0.58040 0.11180  0.00360  0.06410  234 TYR A CE2 
3615 C CZ  . TYR A 234 ? 0.48200 0.69740 0.64430 0.12240  0.00790  0.06760  234 TYR A CZ  
3616 O OH  . TYR A 234 ? 0.44010 0.66800 0.62260 0.13150  0.01110  0.06960  234 TYR A OH  
3626 N N   . LEU A 235 ? 0.39980 0.52450 0.48410 0.09830  0.01130  0.05430  235 LEU A N   
3627 C CA  . LEU A 235 ? 0.37610 0.48020 0.45710 0.10260  0.01660  0.05310  235 LEU A CA  
3628 C C   . LEU A 235 ? 0.40060 0.50830 0.49590 0.11340  0.01810  0.05810  235 LEU A C   
3629 O O   . LEU A 235 ? 0.41290 0.52670 0.51380 0.11880  0.01320  0.06620  235 LEU A O   
3630 C CB  . LEU A 235 ? 0.38910 0.47590 0.45700 0.10080  0.01420  0.05470  235 LEU A CB  
3631 C CG  . LEU A 235 ? 0.42710 0.49160 0.49020 0.10370  0.01820  0.05300  235 LEU A CG  
3632 C CD1 . LEU A 235 ? 0.41870 0.47460 0.47580 0.09940  0.02380  0.04470  235 LEU A CD1 
3633 C CD2 . LEU A 235 ? 0.39420 0.44660 0.44700 0.10110  0.01480  0.05540  235 LEU A CD2 
3645 N N   . VAL A 236 ? 0.40710 0.51110 0.50820 0.11660  0.02510  0.05340  236 VAL A N   
3646 C CA  . VAL A 236 ? 0.45730 0.56210 0.57290 0.12750  0.02780  0.05640  236 VAL A CA  
3647 C C   . VAL A 236 ? 0.47340 0.55350 0.58300 0.13160  0.03000  0.05630  236 VAL A C   
3648 O O   . VAL A 236 ? 0.45160 0.52790 0.56970 0.13980  0.02830  0.06270  236 VAL A O   
3649 C CB  . VAL A 236 ? 0.45520 0.57010 0.58100 0.12920  0.03510  0.05040  236 VAL A CB  
3650 C CG1 . VAL A 236 ? 0.41770 0.53050 0.55850 0.14130  0.03930  0.05180  236 VAL A CG1 
3651 C CG2 . VAL A 236 ? 0.41400 0.55490 0.54900 0.12510  0.03260  0.05120  236 VAL A CG2 
3661 N N   . GLN A 237 ? 0.43500 0.49810 0.53030 0.12570  0.03340  0.04920  237 GLN A N   
3662 C CA  . GLN A 237 ? 0.44920 0.48950 0.53960 0.12890  0.03590  0.04700  237 GLN A CA  
3663 C C   . GLN A 237 ? 0.46300 0.48860 0.53520 0.11990  0.03550  0.04200  237 GLN A C   
3664 O O   . GLN A 237 ? 0.45210 0.48150 0.51660 0.11320  0.03740  0.03690  237 GLN A O   
3665 C CB  . GLN A 237 ? 0.51060 0.54790 0.60930 0.13560  0.04360  0.04110  237 GLN A CB  
3666 C CG  . GLN A 237 ? 0.65630 0.67950 0.76290 0.14450  0.04430  0.04360  237 GLN A CG  
3667 C CD  . GLN A 237 ? 0.75340 0.75210 0.84760 0.14190  0.04670  0.03690  237 GLN A CD  
3668 O OE1 . GLN A 237 ? 0.83220 0.82570 0.91650 0.13790  0.05160  0.02780  237 GLN A OE1 
3669 N NE2 . GLN A 237 ? 0.72700 0.71120 0.82090 0.14340  0.04290  0.04170  237 GLN A NE2 
3678 N N   . GLN A 238 ? 0.46250 0.47200 0.52900 0.11980  0.03280  0.04420  238 GLN A N   
3679 C CA  . GLN A 238 ? 0.46090 0.45690 0.51200 0.11220  0.03140  0.04030  238 GLN A CA  
3680 C C   . GLN A 238 ? 0.49880 0.47400 0.54750 0.11460  0.03280  0.03760  238 GLN A C   
3681 O O   . GLN A 238 ? 0.52020 0.49020 0.57700 0.11980  0.03130  0.04310  238 GLN A O   
3682 C CB  . GLN A 238 ? 0.42030 0.42030 0.46670 0.10760  0.02520  0.04590  238 GLN A CB  
3683 C CG  . GLN A 238 ? 0.42730 0.41570 0.45970 0.10000  0.02390  0.04160  238 GLN A CG  
3684 C CD  . GLN A 238 ? 0.44440 0.43660 0.46900 0.09400  0.02580  0.03560  238 GLN A CD  
3685 O OE1 . GLN A 238 ? 0.45730 0.46330 0.48690 0.09400  0.02760  0.03510  238 GLN A OE1 
3686 N NE2 . GLN A 238 ? 0.41320 0.39230 0.42640 0.08920  0.02580  0.03100  238 GLN A NE2 
3695 N N   . GLU A 239 ? 0.45840 0.42180 0.49590 0.11050  0.03540  0.02960  239 GLU A N   
3696 C CA  . GLU A 239 ? 0.49150 0.43510 0.52470 0.11100  0.03580  0.02550  239 GLU A CA  
3697 C C   . GLU A 239 ? 0.49030 0.42670 0.50850 0.10260  0.03290  0.02220  239 GLU A C   
3698 O O   . GLU A 239 ? 0.45030 0.38590 0.45870 0.09900  0.03540  0.01600  239 GLU A O   
3699 C CB  . GLU A 239 ? 0.53050 0.46750 0.56530 0.11570  0.04230  0.01760  239 GLU A CB  
3700 C CG  . GLU A 239 ? 0.71990 0.64090 0.76170 0.12140  0.04320  0.01630  239 GLU A CG  
3701 C CD  . GLU A 239 ? 0.77220 0.69910 0.83150 0.12970  0.04290  0.02460  239 GLU A CD  
3702 O OE1 . GLU A 239 ? 0.79890 0.71210 0.86480 0.13310  0.04170  0.02700  239 GLU A OE1 
3703 O OE2 . GLU A 239 ? 0.92540 0.87050 0.99240 0.13250  0.04330  0.02910  239 GLU A OE2 
3710 N N   . SER A 240 ? 0.45110 0.38400 0.46810 0.09950  0.02770  0.02690  240 SER A N   
3711 C CA  . SER A 240 ? 0.46710 0.39390 0.47250 0.09240  0.02430  0.02460  240 SER A CA  
3712 C C   . SER A 240 ? 0.46190 0.38330 0.47070 0.09130  0.02000  0.02990  240 SER A C   
3713 O O   . SER A 240 ? 0.47690 0.40370 0.49520 0.09490  0.01930  0.03700  240 SER A O   
3714 C CB  . SER A 240 ? 0.42170 0.36030 0.42150 0.08780  0.02330  0.02520  240 SER A CB  
3715 O OG  . SER A 240 ? 0.42460 0.37620 0.43140 0.08880  0.02120  0.03170  240 SER A OG  
3721 N N   . PRO A 241 ? 0.45010 0.36180 0.45180 0.08640  0.01690  0.02710  241 PRO A N   
3722 C CA  . PRO A 241 ? 0.44760 0.35600 0.45380 0.08470  0.01340  0.03220  241 PRO A CA  
3723 C C   . PRO A 241 ? 0.47170 0.39170 0.47690 0.08190  0.01080  0.03710  241 PRO A C   
3724 O O   . PRO A 241 ? 0.44680 0.36710 0.45630 0.08070  0.00880  0.04210  241 PRO A O   
3725 C CB  . PRO A 241 ? 0.52310 0.41800 0.52300 0.08050  0.01100  0.02620  241 PRO A CB  
3726 C CG  . PRO A 241 ? 0.49930 0.39440 0.48770 0.07850  0.01190  0.01950  241 PRO A CG  
3727 C CD  . PRO A 241 ? 0.49400 0.39650 0.48460 0.08290  0.01700  0.01910  241 PRO A CD  
3735 N N   . PHE A 242 ? 0.43120 0.36070 0.43130 0.08040  0.01130  0.03540  242 PHE A N   
3736 C CA  . PHE A 242 ? 0.43130 0.37180 0.43020 0.07790  0.00930  0.03830  242 PHE A CA  
3737 C C   . PHE A 242 ? 0.44240 0.39320 0.43920 0.07780  0.01110  0.03640  242 PHE A C   
3738 O O   . PHE A 242 ? 0.41170 0.36030 0.40660 0.07870  0.01390  0.03260  242 PHE A O   
3739 C CB  . PHE A 242 ? 0.42360 0.35890 0.41660 0.07300  0.00640  0.03560  242 PHE A CB  
3740 C CG  . PHE A 242 ? 0.41530 0.34510 0.39930 0.07020  0.00620  0.02960  242 PHE A CG  
3741 C CD1 . PHE A 242 ? 0.41820 0.35460 0.39790 0.06790  0.00640  0.02830  242 PHE A CD1 
3742 C CD2 . PHE A 242 ? 0.45710 0.37490 0.43670 0.06960  0.00570  0.02550  242 PHE A CD2 
3743 C CE1 . PHE A 242 ? 0.44150 0.37220 0.41260 0.06510  0.00640  0.02420  242 PHE A CE1 
3744 C CE2 . PHE A 242 ? 0.42380 0.33710 0.39340 0.06690  0.00550  0.02100  242 PHE A CE2 
3745 C CZ  . PHE A 242 ? 0.44580 0.36530 0.41120 0.06480  0.00600  0.02100  242 PHE A CZ  
3755 N N   . VAL A 243 ? 0.39130 0.35420 0.38880 0.07640  0.00980  0.03900  243 VAL A N   
3756 C CA  . VAL A 243 ? 0.39180 0.36390 0.38700 0.07420  0.01050  0.03630  243 VAL A CA  
3757 C C   . VAL A 243 ? 0.37390 0.34860 0.36460 0.06970  0.00800  0.03500  243 VAL A C   
3758 O O   . VAL A 243 ? 0.39780 0.37340 0.38940 0.06960  0.00610  0.03750  243 VAL A O   
3759 C CB  . VAL A 243 ? 0.39190 0.37880 0.39440 0.07740  0.01150  0.03960  243 VAL A CB  
3760 C CG1 . VAL A 243 ? 0.40410 0.38840 0.41270 0.08270  0.01440  0.04050  243 VAL A CG1 
3761 C CG2 . VAL A 243 ? 0.40300 0.39940 0.40890 0.07870  0.00880  0.04550  243 VAL A CG2 
3771 N N   . MET A 244 ? 0.37500 0.35090 0.36140 0.06600  0.00840  0.03110  244 MET A N   
3772 C CA  . MET A 244 ? 0.36700 0.34480 0.35010 0.06200  0.00640  0.02890  244 MET A CA  
3773 C C   . MET A 244 ? 0.38390 0.37440 0.36910 0.05980  0.00670  0.02750  244 MET A C   
3774 O O   . MET A 244 ? 0.38200 0.37410 0.36750 0.05830  0.00890  0.02590  244 MET A O   
3775 C CB  . MET A 244 ? 0.37550 0.34040 0.35200 0.05890  0.00570  0.02550  244 MET A CB  
3776 C CG  . MET A 244 ? 0.36500 0.32950 0.33930 0.05540  0.00380  0.02290  244 MET A CG  
3777 S SD  . MET A 244 ? 0.41170 0.36110 0.37850 0.05230  0.00280  0.02070  244 MET A SD  
3778 C CE  . MET A 244 ? 0.41880 0.36800 0.38600 0.04930  0.00090  0.01780  244 MET A CE  
3788 N N   . MET A 245 ? 0.33800 0.33830 0.32470 0.05930  0.00480  0.02810  245 MET A N   
3789 C CA  . MET A 245 ? 0.36990 0.38350 0.35850 0.05660  0.00410  0.02610  245 MET A CA  
3790 C C   . MET A 245 ? 0.38120 0.39160 0.36560 0.05200  0.00280  0.02090  245 MET A C   
3791 O O   . MET A 245 ? 0.38110 0.38800 0.36320 0.05270  0.00180  0.02050  245 MET A O   
3792 C CB  . MET A 245 ? 0.34260 0.37050 0.33480 0.05980  0.00250  0.03040  245 MET A CB  
3793 C CG  . MET A 245 ? 0.36770 0.39770 0.36550 0.06550  0.00340  0.03670  245 MET A CG  
3794 S SD  . MET A 245 ? 0.38530 0.41910 0.38960 0.06710  0.00600  0.03640  245 MET A SD  
3795 C CE  . MET A 245 ? 0.39050 0.44170 0.39790 0.06280  0.00430  0.03350  245 MET A CE  
3805 N N   . SER A 246 ? 0.34370 0.35490 0.32800 0.04730  0.00310  0.01680  246 SER A N   
3806 C CA  . SER A 246 ? 0.34510 0.35050 0.32640 0.04290  0.00210  0.01140  246 SER A CA  
3807 C C   . SER A 246 ? 0.38200 0.39890 0.36590 0.03820  0.00110  0.00710  246 SER A C   
3808 O O   . SER A 246 ? 0.36910 0.39660 0.35750 0.03720  0.00160  0.00830  246 SER A O   
3809 C CB  . SER A 246 ? 0.41230 0.40170 0.39030 0.04050  0.00330  0.01060  246 SER A CB  
3810 O OG  . SER A 246 ? 0.39580 0.37530 0.37110 0.04430  0.00350  0.01390  246 SER A OG  
3816 N N   . ALA A 247 ? 0.35780 0.37250 0.33960 0.03520  -0.00020 0.00160  247 ALA A N   
3817 C CA  . ALA A 247 ? 0.34290 0.36690 0.32680 0.02980  -0.00160 -0.00420 247 ALA A CA  
3818 C C   . ALA A 247 ? 0.38920 0.40260 0.37050 0.02680  -0.00210 -0.01110 247 ALA A C   
3819 O O   . ALA A 247 ? 0.39740 0.40260 0.37590 0.03040  -0.00180 -0.01110 247 ALA A O   
3820 C CB  . ALA A 247 ? 0.37670 0.42000 0.36130 0.03140  -0.00390 -0.00380 247 ALA A CB  
3826 N N   . PRO A 248 ? 0.40080 0.41460 0.38420 0.02050  -0.00270 -0.01720 248 PRO A N   
3827 C CA  . PRO A 248 ? 0.37190 0.37600 0.35370 0.01810  -0.00320 -0.02500 248 PRO A CA  
3828 C C   . PRO A 248 ? 0.40980 0.42170 0.38800 0.02210  -0.00400 -0.02810 248 PRO A C   
3829 O O   . PRO A 248 ? 0.41470 0.44370 0.39160 0.02310  -0.00530 -0.02700 248 PRO A O   
3830 C CB  . PRO A 248 ? 0.44890 0.45790 0.43450 0.01010  -0.00440 -0.03150 248 PRO A CB  
3831 C CG  . PRO A 248 ? 0.43260 0.44740 0.42250 0.00790  -0.00340 -0.02540 248 PRO A CG  
3832 C CD  . PRO A 248 ? 0.41580 0.44050 0.40420 0.01510  -0.00320 -0.01810 248 PRO A CD  
3840 N N   . PRO A 249 ? 0.41890 0.41970 0.39560 0.02450  -0.00300 -0.03150 249 PRO A N   
3841 C CA  . PRO A 249 ? 0.38820 0.39710 0.36150 0.02880  -0.00250 -0.03340 249 PRO A CA  
3842 C C   . PRO A 249 ? 0.42590 0.45060 0.39610 0.02560  -0.00390 -0.04050 249 PRO A C   
3843 O O   . PRO A 249 ? 0.42540 0.44850 0.39660 0.02010  -0.00500 -0.04890 249 PRO A O   
3844 C CB  . PRO A 249 ? 0.41500 0.40870 0.38970 0.03100  -0.00100 -0.03780 249 PRO A CB  
3845 C CG  . PRO A 249 ? 0.47630 0.45410 0.45440 0.02700  -0.00160 -0.03920 249 PRO A CG  
3846 C CD  . PRO A 249 ? 0.43210 0.41300 0.41080 0.02370  -0.00230 -0.03310 249 PRO A CD  
3854 N N   . ALA A 250 ? 0.36740 0.40750 0.33340 0.02880  -0.00410 -0.03680 250 ALA A N   
3855 C CA  . ALA A 250 ? 0.36700 0.42450 0.32780 0.02650  -0.00590 -0.04220 250 ALA A CA  
3856 C C   . ALA A 250 ? 0.39690 0.46400 0.35210 0.03170  -0.00420 -0.03800 250 ALA A C   
3857 O O   . ALA A 250 ? 0.39500 0.45900 0.35200 0.03640  -0.00270 -0.02860 250 ALA A O   
3858 C CB  . ALA A 250 ? 0.42330 0.49480 0.38590 0.02330  -0.00950 -0.03890 250 ALA A CB  
3864 N N   . GLN A 251 ? 0.41260 0.49130 0.36060 0.03050  -0.00420 -0.04540 251 GLN A N   
3865 C CA  . GLN A 251 ? 0.43290 0.52370 0.37430 0.03470  -0.00230 -0.04060 251 GLN A CA  
3866 C C   . GLN A 251 ? 0.42180 0.52290 0.36350 0.03710  -0.00450 -0.02730 251 GLN A C   
3867 O O   . GLN A 251 ? 0.41060 0.52190 0.35280 0.03470  -0.00870 -0.02570 251 GLN A O   
3868 C CB  . GLN A 251 ? 0.46190 0.56680 0.39360 0.03200  -0.00270 -0.05060 251 GLN A CB  
3869 C CG  . GLN A 251 ? 0.56940 0.66370 0.50090 0.03100  0.00070  -0.06400 251 GLN A CG  
3870 C CD  . GLN A 251 ? 0.59190 0.67770 0.52640 0.03660  0.00620  -0.06110 251 GLN A CD  
3871 O OE1 . GLN A 251 ? 0.61070 0.70610 0.54140 0.04010  0.00840  -0.05320 251 GLN A OE1 
3872 N NE2 . GLN A 251 ? 0.60260 0.67070 0.54450 0.03740  0.00810  -0.06710 251 GLN A NE2 
3881 N N   . TYR A 252 ? 0.38960 0.48840 0.33210 0.04200  -0.00180 -0.01800 252 TYR A N   
3882 C CA  . TYR A 252 ? 0.38500 0.48790 0.33030 0.04510  -0.00320 -0.00490 252 TYR A CA  
3883 C C   . TYR A 252 ? 0.41500 0.52050 0.35790 0.04920  0.00020  0.00310  252 TYR A C   
3884 O O   . TYR A 252 ? 0.44290 0.53920 0.38750 0.05040  0.00400  0.00080  252 TYR A O   
3885 C CB  . TYR A 252 ? 0.36850 0.45600 0.32300 0.04580  -0.00350 -0.00160 252 TYR A CB  
3886 C CG  . TYR A 252 ? 0.39930 0.48940 0.35800 0.04920  -0.00470 0.01000  252 TYR A CG  
3887 C CD1 . TYR A 252 ? 0.43240 0.53300 0.39330 0.04840  -0.00820 0.01250  252 TYR A CD1 
3888 C CD2 . TYR A 252 ? 0.39000 0.47180 0.35160 0.05320  -0.00230 0.01810  252 TYR A CD2 
3889 C CE1 . TYR A 252 ? 0.43780 0.54040 0.40390 0.05240  -0.00900 0.02270  252 TYR A CE1 
3890 C CE2 . TYR A 252 ? 0.39380 0.47630 0.36000 0.05660  -0.00320 0.02800  252 TYR A CE2 
3891 C CZ  . TYR A 252 ? 0.40550 0.49810 0.37400 0.05650  -0.00640 0.03010  252 TYR A CZ  
3892 O OH  . TYR A 252 ? 0.45390 0.54720 0.42800 0.06070  -0.00710 0.03940  252 TYR A OH  
3902 N N   . GLU A 253 ? 0.43390 0.55220 0.37370 0.05120  -0.00140 0.01300  253 GLU A N   
3903 C CA  . GLU A 253 ? 0.43460 0.55580 0.37220 0.05430  0.00200  0.02210  253 GLU A CA  
3904 C C   . GLU A 253 ? 0.45850 0.56790 0.40520 0.05760  0.00240  0.03250  253 GLU A C   
3905 O O   . GLU A 253 ? 0.45510 0.56510 0.40590 0.05910  -0.00080 0.03850  253 GLU A O   
3906 C CB  . GLU A 253 ? 0.50140 0.64240 0.42940 0.05470  0.00020  0.02830  253 GLU A CB  
3907 C CG  . GLU A 253 ? 0.61600 0.75880 0.54400 0.05800  0.00280  0.04210  253 GLU A CG  
3908 C CD  . GLU A 253 ? 0.72290 0.88470 0.63840 0.05770  0.00300  0.04660  253 GLU A CD  
3909 O OE1 . GLU A 253 ? 0.65780 0.83300 0.56810 0.05740  -0.00230 0.04910  253 GLU A OE1 
3910 O OE2 . GLU A 253 ? 0.70960 0.87380 0.62070 0.05770  0.00840  0.04810  253 GLU A OE2 
3917 N N   . LEU A 254 ? 0.41180 0.51120 0.36250 0.05880  0.00640  0.03400  254 LEU A N   
3918 C CA  . LEU A 254 ? 0.43030 0.51820 0.38900 0.06130  0.00710  0.04300  254 LEU A CA  
3919 C C   . LEU A 254 ? 0.44120 0.53680 0.39820 0.06310  0.00920  0.05430  254 LEU A C   
3920 O O   . LEU A 254 ? 0.47150 0.57210 0.42540 0.06220  0.01320  0.05380  254 LEU A O   
3921 C CB  . LEU A 254 ? 0.41840 0.49130 0.38330 0.06090  0.00930  0.03770  254 LEU A CB  
3922 C CG  . LEU A 254 ? 0.43040 0.49190 0.39810 0.05950  0.00720  0.02920  254 LEU A CG  
3923 C CD1 . LEU A 254 ? 0.37980 0.42960 0.35190 0.05940  0.00910  0.02420  254 LEU A CD1 
3924 C CD2 . LEU A 254 ? 0.42690 0.48070 0.39900 0.06060  0.00470  0.03370  254 LEU A CD2 
3936 N N   . LYS A 255 ? 0.43490 0.53150 0.39460 0.06550  0.00700  0.06480  255 LYS A N   
3937 C CA  . LYS A 255 ? 0.45140 0.55470 0.40950 0.06720  0.00850  0.07750  255 LYS A CA  
3938 C C   . LYS A 255 ? 0.47130 0.55970 0.43920 0.06830  0.01090  0.08400  255 LYS A C   
3939 O O   . LYS A 255 ? 0.42950 0.50530 0.40510 0.06990  0.00900  0.08440  255 LYS A O   
3940 C CB  . LYS A 255 ? 0.47080 0.58450 0.42670 0.06970  0.00410  0.08580  255 LYS A CB  
3943 N N   . HIS A 256 ? 0.42120 0.51140 0.38890 0.06690  0.01520  0.08830  256 HIS A N   
3944 C CA  . HIS A 256 ? 0.46980 0.54740 0.44730 0.06690  0.01750  0.09470  256 HIS A CA  
3945 C C   . HIS A 256 ? 0.45740 0.52680 0.44110 0.06990  0.01490  0.10450  256 HIS A C   
3946 O O   . HIS A 256 ? 0.45100 0.52900 0.43100 0.07210  0.01330  0.11360  256 HIS A O   
3947 C CB  . HIS A 256 ? 0.47460 0.56080 0.45030 0.06480  0.02270  0.10110  256 HIS A CB  
3948 C CG  . HIS A 256 ? 0.48640 0.56150 0.47290 0.06380  0.02510  0.10890  256 HIS A CG  
3949 N ND1 . HIS A 256 ? 0.54480 0.62270 0.53230 0.06350  0.02730  0.12300  256 HIS A ND1 
3950 C CD2 . HIS A 256 ? 0.50850 0.57030 0.50540 0.06230  0.02550  0.10450  256 HIS A CD2 
3951 C CE1 . HIS A 256 ? 0.57820 0.64400 0.57720 0.06170  0.02910  0.12650  256 HIS A CE1 
3952 N NE2 . HIS A 256 ? 0.53150 0.58800 0.53610 0.06090  0.02780  0.11510  256 HIS A NE2 
3960 N N   . GLY A 257 ? 0.44250 0.49520 0.43540 0.07010  0.01440  0.10250  257 GLY A N   
3961 C CA  . GLY A 257 ? 0.47440 0.51650 0.47460 0.07310  0.01280  0.11020  257 GLY A CA  
3962 C C   . GLY A 257 ? 0.45390 0.49470 0.45450 0.07670  0.00910  0.10740  257 GLY A C   
3963 O O   . GLY A 257 ? 0.49290 0.52530 0.50020 0.08010  0.00810  0.11340  257 GLY A O   
3967 N N   . THR A 258 ? 0.41960 0.46860 0.41410 0.07600  0.00730  0.09850  258 THR A N   
3968 C CA  . THR A 258 ? 0.42450 0.47520 0.42010 0.07880  0.00420  0.09610  258 THR A CA  
3969 C C   . THR A 258 ? 0.41990 0.45970 0.41750 0.07750  0.00400  0.08510  258 THR A C   
3970 O O   . THR A 258 ? 0.42930 0.47050 0.42830 0.07920  0.00220  0.08210  258 THR A O   
3971 C CB  . THR A 258 ? 0.41440 0.48380 0.40220 0.07850  0.00180  0.09470  258 THR A CB  
3972 O OG1 . THR A 258 ? 0.44260 0.51540 0.42400 0.07420  0.00270  0.08400  258 THR A OG1 
3973 C CG2 . THR A 258 ? 0.47860 0.56080 0.46210 0.07980  0.00140  0.10620  258 THR A CG2 
3981 N N   . PHE A 259 ? 0.39920 0.42950 0.39690 0.07450  0.00570  0.07950  259 PHE A N   
3982 C CA  . PHE A 259 ? 0.41290 0.43300 0.41080 0.07280  0.00520  0.06980  259 PHE A CA  
3983 C C   . PHE A 259 ? 0.39780 0.40560 0.39930 0.07100  0.00640  0.06870  259 PHE A C   
3984 O O   . PHE A 259 ? 0.42150 0.43100 0.42530 0.07010  0.00810  0.07400  259 PHE A O   
3985 C CB  . PHE A 259 ? 0.41220 0.44030 0.40380 0.07020  0.00440  0.06140  259 PHE A CB  
3986 C CG  . PHE A 259 ? 0.39010 0.42210 0.37850 0.06760  0.00600  0.05850  259 PHE A CG  
3987 C CD1 . PHE A 259 ? 0.39140 0.43650 0.37630 0.06760  0.00730  0.06320  259 PHE A CD1 
3988 C CD2 . PHE A 259 ? 0.39460 0.41780 0.38380 0.06560  0.00640  0.05120  259 PHE A CD2 
3989 C CE1 . PHE A 259 ? 0.39270 0.44230 0.37500 0.06560  0.00990  0.05980  259 PHE A CE1 
3990 C CE2 . PHE A 259 ? 0.40720 0.43470 0.39540 0.06410  0.00830  0.04820  259 PHE A CE2 
3991 C CZ  . PHE A 259 ? 0.36490 0.40570 0.34980 0.06410  0.01050  0.05210  259 PHE A CZ  
4001 N N   . THR A 260 ? 0.36460 0.36090 0.36670 0.07000  0.00550  0.06190  260 THR A N   
4002 C CA  . THR A 260 ? 0.35420 0.34000 0.35970 0.06800  0.00550  0.05990  260 THR A CA  
4003 C C   . THR A 260 ? 0.36420 0.35360 0.36750 0.06550  0.00540  0.05420  260 THR A C   
4004 O O   . THR A 260 ? 0.38180 0.37390 0.38860 0.06420  0.00680  0.05590  260 THR A O   
4005 C CB  . THR A 260 ? 0.40560 0.37750 0.41170 0.06820  0.00400  0.05580  260 THR A CB  
4006 O OG1 . THR A 260 ? 0.45480 0.42310 0.46410 0.07130  0.00470  0.06030  260 THR A OG1 
4007 C CG2 . THR A 260 ? 0.43470 0.39680 0.44430 0.06580  0.00280  0.05370  260 THR A CG2 
4015 N N   . CYS A 261 ? 0.37790 0.40230 0.37780 0.03560  0.02380  0.03830  261 CYS A N   
4016 C CA  . CYS A 261 ? 0.36570 0.39180 0.36100 0.03380  0.02430  0.03310  261 CYS A CA  
4017 C C   . CYS A 261 ? 0.37230 0.40100 0.36630 0.03370  0.02050  0.03210  261 CYS A C   
4018 O O   . CYS A 261 ? 0.37750 0.40850 0.37560 0.03480  0.01790  0.03520  261 CYS A O   
4019 C CB  . CYS A 261 ? 0.34440 0.37000 0.34420 0.03470  0.02710  0.02750  261 CYS A CB  
4020 S SG  . CYS A 261 ? 0.38340 0.40990 0.39060 0.03860  0.02590  0.02590  261 CYS A SG  
4026 N N   . ALA A 262 ? 0.38330 0.41180 0.37280 0.03220  0.02070  0.02760  262 ALA A N   
4027 C CA  . ALA A 262 ? 0.33240 0.36180 0.32110 0.03070  0.01750  0.02600  262 ALA A CA  
4028 C C   . ALA A 262 ? 0.33930 0.36520 0.32620 0.03070  0.01950  0.02040  262 ALA A C   
4029 O O   . ALA A 262 ? 0.37320 0.39790 0.35730 0.03180  0.02260  0.01760  262 ALA A O   
4030 C CB  . ALA A 262 ? 0.33740 0.37040 0.31950 0.02810  0.01390  0.02710  262 ALA A CB  
4036 N N   . SER A 263 ? 0.32000 0.34410 0.30920 0.02940  0.01790  0.01900  263 SER A N   
4037 C CA  . SER A 263 ? 0.32640 0.34490 0.31420 0.02970  0.01980  0.01440  263 SER A CA  
4038 C C   . SER A 263 ? 0.35210 0.36860 0.33590 0.02550  0.01710  0.01020  263 SER A C   
4039 O O   . SER A 263 ? 0.35460 0.37430 0.34160 0.02210  0.01340  0.01140  263 SER A O   
4040 C CB  . SER A 263 ? 0.43640 0.45260 0.43120 0.03210  0.02140  0.01650  263 SER A CB  
4041 O OG  . SER A 263 ? 0.40680 0.42550 0.40320 0.03660  0.02370  0.01800  263 SER A OG  
4047 N N   . GLU A 264 ? 0.34950 0.36150 0.32720 0.02590  0.01900  0.00470  264 GLU A N   
4048 C CA  . GLU A 264 ? 0.38420 0.39300 0.35690 0.02240  0.01690  -0.00160 264 GLU A CA  
4049 C C   . GLU A 264 ? 0.37780 0.37630 0.35370 0.02320  0.01960  -0.00540 264 GLU A C   
4050 O O   . GLU A 264 ? 0.39210 0.38690 0.36790 0.02820  0.02380  -0.00540 264 GLU A O   
4051 C CB  . GLU A 264 ? 0.37550 0.38690 0.33740 0.02330  0.01800  -0.00550 264 GLU A CB  
4052 C CG  . GLU A 264 ? 0.40610 0.41440 0.36080 0.02060  0.01620  -0.01400 264 GLU A CG  
4053 C CD  . GLU A 264 ? 0.47040 0.48110 0.41400 0.02290  0.01900  -0.01790 264 GLU A CD  
4054 O OE1 . GLU A 264 ? 0.42520 0.43130 0.36850 0.02680  0.02390  -0.02070 264 GLU A OE1 
4055 O OE2 . GLU A 264 ? 0.48700 0.50510 0.42180 0.02140  0.01660  -0.01800 264 GLU A OE2 
4062 N N   . TYR A 265 ? 0.38900 0.38270 0.36790 0.01850  0.01730  -0.00900 265 TYR A N   
4063 C CA  . TYR A 265 ? 0.37290 0.35400 0.35510 0.01880  0.02050  -0.01250 265 TYR A CA  
4064 C C   . TYR A 265 ? 0.41260 0.38790 0.38970 0.01480  0.01860  -0.02270 265 TYR A C   
4065 O O   . TYR A 265 ? 0.38400 0.36180 0.36380 0.00820  0.01400  -0.02600 265 TYR A O   
4066 C CB  . TYR A 265 ? 0.41230 0.39010 0.40580 0.01630  0.02100  -0.00740 265 TYR A CB  
4067 C CG  . TYR A 265 ? 0.39940 0.36270 0.39620 0.01860  0.02590  -0.00790 265 TYR A CG  
4068 C CD1 . TYR A 265 ? 0.39720 0.35780 0.39310 0.02670  0.03050  -0.00310 265 TYR A CD1 
4069 C CD2 . TYR A 265 ? 0.40140 0.35360 0.40220 0.01320  0.02600  -0.01360 265 TYR A CD2 
4070 C CE1 . TYR A 265 ? 0.40090 0.34850 0.39910 0.03030  0.03520  -0.00220 265 TYR A CE1 
4071 C CE2 . TYR A 265 ? 0.42440 0.36100 0.42820 0.01610  0.03140  -0.01320 265 TYR A CE2 
4072 C CZ  . TYR A 265 ? 0.41840 0.35280 0.42050 0.02520  0.03600  -0.00660 265 TYR A CZ  
4073 O OH  . TYR A 265 ? 0.46380 0.38290 0.46830 0.02970  0.04160  -0.00470 265 TYR A OH  
4083 N N   . THR A 266 ? 0.42030 0.38840 0.39090 0.01890  0.02210  -0.02830 266 THR A N   
4084 C CA  . THR A 266 ? 0.43880 0.40010 0.40360 0.01620  0.02110  -0.03950 266 THR A CA  
4085 C C   . THR A 266 ? 0.48200 0.42600 0.45380 0.01580  0.02440  -0.04280 266 THR A C   
4086 O O   . THR A 266 ? 0.50790 0.44450 0.48280 0.02210  0.02960  -0.03800 266 THR A O   
4087 C CB  . THR A 266 ? 0.44860 0.41270 0.40190 0.02160  0.02380  -0.04410 266 THR A CB  
4088 O OG1 . THR A 266 ? 0.48410 0.46310 0.43180 0.02180  0.02170  -0.03940 266 THR A OG1 
4089 C CG2 . THR A 266 ? 0.51350 0.47140 0.45910 0.01950  0.02280  -0.05690 266 THR A CG2 
4097 N N   . GLY A 267 ? 0.50240 0.44000 0.47690 0.00850  0.02140  -0.05090 267 GLY A N   
4098 C CA  . GLY A 267 ? 0.53350 0.45220 0.51540 0.00680  0.02480  -0.05500 267 GLY A CA  
4099 C C   . GLY A 267 ? 0.51860 0.43510 0.51450 -0.00140 0.02320  -0.05110 267 GLY A C   
4100 O O   . GLY A 267 ? 0.57820 0.50910 0.57810 -0.00560 0.01880  -0.04620 267 GLY A O   
4104 N N   . ASN A 268 ? 0.56930 0.46710 0.57350 -0.00340 0.02740  -0.05300 268 ASN A N   
4105 C CA  . ASN A 268 ? 0.66400 0.55810 0.68350 -0.01120 0.02790  -0.04810 268 ASN A CA  
4106 C C   . ASN A 268 ? 0.54930 0.44420 0.57380 -0.00520 0.03320  -0.03260 268 ASN A C   
4107 O O   . ASN A 268 ? 0.60490 0.49970 0.62210 0.00500  0.03670  -0.02710 268 ASN A O   
4108 C CB  . ASN A 268 ? 0.78660 0.65880 0.81400 -0.01670 0.03110  -0.05620 268 ASN A CB  
4109 C CG  . ASN A 268 ? 1.08590 0.96070 1.11410 -0.02720 0.02410  -0.07170 268 ASN A CG  
4110 O OD1 . ASN A 268 ? 0.88710 0.76400 0.90280 -0.02510 0.02100  -0.08290 268 ASN A OD1 
4111 N ND2 . ASN A 268 ? 1.25290 1.12970 1.29610 -0.03840 0.02160  -0.07250 268 ASN A ND2 
4118 N N   . TYR A 269 ? 0.56940 0.46690 0.60700 -0.01150 0.03370  -0.02580 269 TYR A N   
4119 C CA  . TYR A 269 ? 0.57550 0.47460 0.61760 -0.00610 0.03910  -0.01130 269 TYR A CA  
4120 C C   . TYR A 269 ? 0.54430 0.42460 0.58470 0.00220  0.04700  -0.00650 269 TYR A C   
4121 O O   . TYR A 269 ? 0.54770 0.40870 0.59280 -0.00080 0.05040  -0.01110 269 TYR A O   
4122 C CB  . TYR A 269 ? 0.58560 0.48890 0.64320 -0.01500 0.03950  -0.00590 269 TYR A CB  
4123 C CG  . TYR A 269 ? 0.59190 0.51670 0.65190 -0.02110 0.03170  -0.00860 269 TYR A CG  
4124 C CD1 . TYR A 269 ? 0.61950 0.56120 0.67470 -0.01520 0.02980  -0.00130 269 TYR A CD1 
4125 C CD2 . TYR A 269 ? 0.58980 0.51810 0.65710 -0.03210 0.02590  -0.01870 269 TYR A CD2 
4126 C CE1 . TYR A 269 ? 0.51570 0.47610 0.57310 -0.01930 0.02300  -0.00260 269 TYR A CE1 
4127 C CE2 . TYR A 269 ? 0.57580 0.52530 0.64500 -0.03620 0.01830  -0.02030 269 TYR A CE2 
4128 C CZ  . TYR A 269 ? 0.52330 0.48810 0.58740 -0.02930 0.01720  -0.01170 269 TYR A CZ  
4129 O OH  . TYR A 269 ? 0.55540 0.54030 0.62150 -0.03200 0.01010  -0.01210 269 TYR A OH  
4139 N N   . GLN A 270 ? 0.53800 0.42400 0.57180 0.01290  0.04970  0.00260  270 GLN A N   
4140 C CA  . GLN A 270 ? 0.51060 0.38320 0.54140 0.02320  0.05640  0.00880  270 GLN A CA  
4141 C C   . GLN A 270 ? 0.57730 0.43760 0.60080 0.02790  0.05710  -0.00080 270 GLN A C   
4142 O O   . GLN A 270 ? 0.53360 0.37820 0.55690 0.03530  0.06300  0.00270  270 GLN A O   
4143 C CB  . GLN A 270 ? 0.58650 0.44370 0.62820 0.02090  0.06340  0.01750  270 GLN A CB  
4144 C CG  . GLN A 270 ? 0.64000 0.50910 0.68970 0.01690  0.06430  0.02770  270 GLN A CG  
4145 C CD  . GLN A 270 ? 0.61150 0.46500 0.67110 0.01570  0.07280  0.03800  270 GLN A CD  
4146 O OE1 . GLN A 270 ? 0.65560 0.49620 0.72650 0.00550  0.07450  0.03410  270 GLN A OE1 
4147 N NE2 . GLN A 270 ? 0.60340 0.45870 0.65920 0.02600  0.07830  0.05130  270 GLN A NE2 
4156 N N   . CYS A 271 ? 0.54910 0.41670 0.56630 0.02460  0.05160  -0.01230 271 CYS A N   
4157 C CA  . CYS A 271 ? 0.55160 0.41090 0.56040 0.03040  0.05270  -0.02160 271 CYS A CA  
4158 C C   . CYS A 271 ? 0.53500 0.41130 0.53440 0.02920  0.04680  -0.02960 271 CYS A C   
4159 O O   . CYS A 271 ? 0.59870 0.47140 0.59330 0.02590  0.04470  -0.04170 271 CYS A O   
4160 C CB  . CYS A 271 ? 0.66640 0.50340 0.68020 0.02520  0.05510  -0.03050 271 CYS A CB  
4161 S SG  . CYS A 271 ? 0.83260 0.67050 0.85520 0.00810  0.04930  -0.03990 271 CYS A SG  
4167 N N   . GLY A 272 ? 0.50740 0.40170 0.50370 0.03230  0.04470  -0.02280 272 GLY A N   
4168 C CA  . GLY A 272 ? 0.48690 0.39720 0.47470 0.03190  0.04030  -0.02750 272 GLY A CA  
4169 C C   . GLY A 272 ? 0.43040 0.35250 0.41430 0.04060  0.04170  -0.02120 272 GLY A C   
4170 O O   . GLY A 272 ? 0.47370 0.39050 0.45860 0.04900  0.04600  -0.01700 272 GLY A O   
4174 N N   . HIS A 273 ? 0.42680 0.36490 0.40690 0.03880  0.03810  -0.02060 273 HIS A N   
4175 C CA  . HIS A 273 ? 0.40650 0.35640 0.38360 0.04540  0.03920  -0.01720 273 HIS A CA  
4176 C C   . HIS A 273 ? 0.41740 0.38140 0.39380 0.04090  0.03520  -0.01420 273 HIS A C   
4177 O O   . HIS A 273 ? 0.39850 0.36530 0.37220 0.03450  0.03160  -0.01770 273 HIS A O   
4178 C CB  . HIS A 273 ? 0.43540 0.38570 0.40550 0.04990  0.04150  -0.02460 273 HIS A CB  
4179 C CG  . HIS A 273 ? 0.41240 0.37580 0.38150 0.05580  0.04290  -0.02210 273 HIS A CG  
4180 N ND1 . HIS A 273 ? 0.41030 0.37420 0.38260 0.06460  0.04610  -0.01890 273 HIS A ND1 
4181 C CD2 . HIS A 273 ? 0.41870 0.39550 0.38460 0.05410  0.04180  -0.02230 273 HIS A CD2 
4182 C CE1 . HIS A 273 ? 0.41560 0.39390 0.38800 0.06720  0.04630  -0.01840 273 HIS A CE1 
4183 N NE2 . HIS A 273 ? 0.41850 0.40370 0.38730 0.06060  0.04420  -0.02020 273 HIS A NE2 
4192 N N   . TYR A 274 ? 0.39220 0.36520 0.37120 0.04470  0.03570  -0.00800 274 TYR A N   
4193 C CA  . TYR A 274 ? 0.36160 0.34620 0.34090 0.04160  0.03270  -0.00470 274 TYR A CA  
4194 C C   . TYR A 274 ? 0.38310 0.37650 0.35780 0.04340  0.03360  -0.00700 274 TYR A C   
4195 O O   . TYR A 274 ? 0.37630 0.37110 0.35080 0.04900  0.03660  -0.00860 274 TYR A O   
4196 C CB  . TYR A 274 ? 0.35030 0.33940 0.33550 0.04420  0.03290  0.00250  274 TYR A CB  
4197 C CG  . TYR A 274 ? 0.34450 0.33040 0.33540 0.04090  0.03190  0.00700  274 TYR A CG  
4198 C CD1 . TYR A 274 ? 0.33210 0.32370 0.32530 0.03540  0.02840  0.00870  274 TYR A CD1 
4199 C CD2 . TYR A 274 ? 0.35380 0.33200 0.34850 0.04400  0.03500  0.01080  274 TYR A CD2 
4200 C CE1 . TYR A 274 ? 0.34450 0.33540 0.34470 0.03230  0.02790  0.01290  274 TYR A CE1 
4201 C CE2 . TYR A 274 ? 0.33990 0.31620 0.34080 0.04060  0.03510  0.01560  274 TYR A CE2 
4202 C CZ  . TYR A 274 ? 0.35720 0.34060 0.36150 0.03460  0.03150  0.01630  274 TYR A CZ  
4203 O OH  . TYR A 274 ? 0.33360 0.31760 0.34580 0.03120  0.03200  0.02130  274 TYR A OH  
4213 N N   . LYS A 275 ? 0.38690 0.38690 0.35880 0.03890  0.03110  -0.00630 275 LYS A N   
4214 C CA  . LYS A 275 ? 0.33860 0.34740 0.30850 0.03960  0.03250  -0.00560 275 LYS A CA  
4215 C C   . LYS A 275 ? 0.33590 0.35010 0.30950 0.03710  0.03010  0.00030  275 LYS A C   
4216 O O   . LYS A 275 ? 0.35040 0.36310 0.32630 0.03450  0.02700  0.00310  275 LYS A O   
4217 C CB  . LYS A 275 ? 0.33730 0.34820 0.29830 0.03760  0.03330  -0.00990 275 LYS A CB  
4218 C CG  . LYS A 275 ? 0.38260 0.38800 0.33920 0.04050  0.03590  -0.01700 275 LYS A CG  
4219 C CD  . LYS A 275 ? 0.41920 0.42890 0.36570 0.03930  0.03730  -0.02140 275 LYS A CD  
4220 C CE  . LYS A 275 ? 0.47240 0.47560 0.41460 0.04280  0.04010  -0.02980 275 LYS A CE  
4221 N NZ  . LYS A 275 ? 0.49790 0.50460 0.42860 0.04210  0.04140  -0.03560 275 LYS A NZ  
4235 N N   . HIS A 276 ? 0.35620 0.37670 0.33110 0.03770  0.03200  0.00180  276 HIS A N   
4236 C CA  . HIS A 276 ? 0.35190 0.37600 0.33090 0.03610  0.03080  0.00680  276 HIS A CA  
4237 C C   . HIS A 276 ? 0.35780 0.38510 0.33200 0.03310  0.03160  0.00880  276 HIS A C   
4238 O O   . HIS A 276 ? 0.38550 0.41560 0.35650 0.03320  0.03510  0.00660  276 HIS A O   
4239 C CB  . HIS A 276 ? 0.36460 0.39250 0.35080 0.03920  0.03260  0.00660  276 HIS A CB  
4240 C CG  . HIS A 276 ? 0.33960 0.36950 0.33090 0.03790  0.03180  0.01010  276 HIS A CG  
4241 N ND1 . HIS A 276 ? 0.37120 0.39990 0.36630 0.03930  0.02960  0.01260  276 HIS A ND1 
4242 C CD2 . HIS A 276 ? 0.34220 0.37440 0.33570 0.03570  0.03350  0.01160  276 HIS A CD2 
4243 C CE1 . HIS A 276 ? 0.34250 0.37250 0.34170 0.03840  0.02970  0.01460  276 HIS A CE1 
4244 N NE2 . HIS A 276 ? 0.36970 0.40080 0.36830 0.03590  0.03200  0.01420  276 HIS A NE2 
4252 N N   . ILE A 277 ? 0.33890 0.36640 0.31250 0.03100  0.02890  0.01380  277 ILE A N   
4253 C CA  . ILE A 277 ? 0.35010 0.38010 0.31900 0.02910  0.02990  0.01800  277 ILE A CA  
4254 C C   . ILE A 277 ? 0.39600 0.42530 0.37230 0.02930  0.03040  0.02330  277 ILE A C   
4255 O O   . ILE A 277 ? 0.39640 0.42460 0.37760 0.03030  0.02740  0.02530  277 ILE A O   
4256 C CB  . ILE A 277 ? 0.37420 0.40540 0.33450 0.02760  0.02590  0.01930  277 ILE A CB  
4257 C CG1 . ILE A 277 ? 0.44460 0.47510 0.39780 0.02730  0.02580  0.01210  277 ILE A CG1 
4258 C CG2 . ILE A 277 ? 0.39840 0.43280 0.35200 0.02700  0.02750  0.02520  277 ILE A CG2 
4259 C CD1 . ILE A 277 ? 0.43400 0.46100 0.39030 0.02650  0.02190  0.00840  277 ILE A CD1 
4271 N N   . THR A 278 ? 0.35650 0.38650 0.33440 0.02820  0.03470  0.02530  278 THR A N   
4272 C CA  . THR A 278 ? 0.38420 0.41170 0.36980 0.02780  0.03590  0.02950  278 THR A CA  
4273 C C   . THR A 278 ? 0.38530 0.41140 0.36610 0.02620  0.03860  0.03690  278 THR A C   
4274 O O   . THR A 278 ? 0.41550 0.44440 0.39040 0.02470  0.04230  0.03730  278 THR A O   
4275 C CB  . THR A 278 ? 0.38620 0.41480 0.38130 0.02750  0.03900  0.02460  278 THR A CB  
4276 O OG1 . THR A 278 ? 0.39730 0.42210 0.40030 0.02650  0.04040  0.02720  278 THR A OG1 
4277 C CG2 . THR A 278 ? 0.40530 0.43860 0.39930 0.02570  0.04350  0.02170  278 THR A CG2 
4285 N N   . SER A 279 ? 0.38510 0.40740 0.36820 0.02730  0.03700  0.04320  279 SER A N   
4286 C CA  . SER A 279 ? 0.40100 0.42100 0.37910 0.02710  0.03950  0.05220  279 SER A CA  
4287 C C   . SER A 279 ? 0.42700 0.44050 0.41500 0.02510  0.04510  0.05460  279 SER A C   
4288 O O   . SER A 279 ? 0.43950 0.44740 0.43610 0.02640  0.04420  0.05510  279 SER A O   
4289 C CB  . SER A 279 ? 0.41950 0.43960 0.39450 0.03040  0.03430  0.05850  279 SER A CB  
4290 O OG  . SER A 279 ? 0.43200 0.44970 0.40180 0.03150  0.03680  0.06860  279 SER A OG  
4296 N N   . LYS A 280 ? 0.44930 0.46370 0.43680 0.02170  0.05120  0.05570  280 LYS A N   
4297 C CA  . LYS A 280 ? 0.45930 0.46760 0.45760 0.01820  0.05750  0.05770  280 LYS A CA  
4298 C C   . LYS A 280 ? 0.47460 0.48020 0.46610 0.01710  0.06320  0.06880  280 LYS A C   
4299 O O   . LYS A 280 ? 0.49730 0.50100 0.47960 0.02090  0.06070  0.07720  280 LYS A O   
4300 C CB  . LYS A 280 ? 0.47720 0.49090 0.48440 0.01460  0.06020  0.04820  280 LYS A CB  
4301 C CG  . LYS A 280 ? 0.47760 0.49610 0.48690 0.01720  0.05440  0.03860  280 LYS A CG  
4302 C CD  . LYS A 280 ? 0.46780 0.48140 0.48620 0.01890  0.05120  0.03540  280 LYS A CD  
4303 C CE  . LYS A 280 ? 0.56640 0.57340 0.59700 0.01530  0.05540  0.03530  280 LYS A CE  
4304 N NZ  . LYS A 280 ? 0.61590 0.62060 0.65450 0.01750  0.05190  0.02850  280 LYS A NZ  
4318 N N   . GLU A 281 ? 0.47410 0.48070 0.47010 0.01230  0.07080  0.06960  281 GLU A N   
4319 C CA  . GLU A 281 ? 0.48520 0.49000 0.47340 0.01150  0.07740  0.08140  281 GLU A CA  
4320 C C   . GLU A 281 ? 0.50520 0.51930 0.47470 0.01520  0.07500  0.08350  281 GLU A C   
4321 O O   . GLU A 281 ? 0.50050 0.51440 0.45870 0.01710  0.07800  0.09450  281 GLU A O   
4322 C CB  . GLU A 281 ? 0.51930 0.52510 0.51760 0.00490  0.08700  0.08150  281 GLU A CB  
4323 C CG  . GLU A 281 ? 0.56840 0.58700 0.56880 0.00250  0.08830  0.07110  281 GLU A CG  
4324 C CD  . GLU A 281 ? 0.55520 0.57600 0.57150 0.00040  0.08500  0.05850  281 GLU A CD  
4325 O OE1 . GLU A 281 ? 0.48110 0.49480 0.50230 0.00220  0.07940  0.05580  281 GLU A OE1 
4326 O OE2 . GLU A 281 ? 0.52590 0.55670 0.54920 -0.00250 0.08790  0.05140  281 GLU A OE2 
4333 N N   . THR A 282 ? 0.49040 0.51260 0.45630 0.01630  0.07010  0.07310  282 THR A N   
4334 C CA  . THR A 282 ? 0.46820 0.49810 0.41750 0.01980  0.06580  0.07180  282 THR A CA  
4335 C C   . THR A 282 ? 0.45180 0.48370 0.40390 0.02120  0.05820  0.06080  282 THR A C   
4336 O O   . THR A 282 ? 0.43410 0.46190 0.39890 0.02040  0.05630  0.05640  282 THR A O   
4337 C CB  . THR A 282 ? 0.50570 0.54370 0.44670 0.01850  0.07260  0.07150  282 THR A CB  
4338 O OG1 . THR A 282 ? 0.48090 0.52560 0.40420 0.02220  0.06850  0.07020  282 THR A OG1 
4339 C CG2 . THR A 282 ? 0.47700 0.51980 0.42830 0.01580  0.07540  0.06080  282 THR A CG2 
4347 N N   . LEU A 283 ? 0.41860 0.45640 0.35890 0.02330  0.05400  0.05630  283 LEU A N   
4348 C CA  . LEU A 283 ? 0.39480 0.43310 0.33770 0.02430  0.04770  0.04670  283 LEU A CA  
4349 C C   . LEU A 283 ? 0.39340 0.43490 0.33950 0.02350  0.05100  0.03770  283 LEU A C   
4350 O O   . LEU A 283 ? 0.42250 0.46920 0.35950 0.02390  0.05410  0.03520  283 LEU A O   
4351 C CB  . LEU A 283 ? 0.39810 0.44020 0.32870 0.02630  0.04110  0.04530  283 LEU A CB  
4352 C CG  . LEU A 283 ? 0.44580 0.48760 0.37360 0.02820  0.03620  0.05340  283 LEU A CG  
4353 C CD1 . LEU A 283 ? 0.49340 0.54220 0.40830 0.02950  0.02980  0.05070  283 LEU A CD1 
4354 C CD2 . LEU A 283 ? 0.49410 0.53100 0.43510 0.02850  0.03260  0.05300  283 LEU A CD2 
4366 N N   . TYR A 284 ? 0.35970 0.39910 0.31830 0.02330  0.05020  0.03260  284 TYR A N   
4367 C CA  . TYR A 284 ? 0.37070 0.41400 0.33370 0.02390  0.05250  0.02450  284 TYR A CA  
4368 C C   . TYR A 284 ? 0.37580 0.41700 0.33760 0.02660  0.04690  0.01810  284 TYR A C   
4369 O O   . TYR A 284 ? 0.37360 0.41060 0.33920 0.02710  0.04220  0.01920  284 TYR A O   
4370 C CB  . TYR A 284 ? 0.37030 0.41470 0.34810 0.02210  0.05560  0.02320  284 TYR A CB  
4371 C CG  . TYR A 284 ? 0.37180 0.41800 0.35370 0.01830  0.06250  0.02850  284 TYR A CG  
4372 C CD1 . TYR A 284 ? 0.39550 0.44890 0.37390 0.01740  0.06880  0.02800  284 TYR A CD1 
4373 C CD2 . TYR A 284 ? 0.44350 0.48380 0.43330 0.01560  0.06350  0.03400  284 TYR A CD2 
4374 C CE1 . TYR A 284 ? 0.44150 0.49680 0.42460 0.01320  0.07620  0.03390  284 TYR A CE1 
4375 C CE2 . TYR A 284 ? 0.44320 0.48340 0.43810 0.01140  0.07060  0.03940  284 TYR A CE2 
4376 C CZ  . TYR A 284 ? 0.41660 0.46460 0.40840 0.00990  0.07720  0.03970  284 TYR A CZ  
4377 O OH  . TYR A 284 ? 0.45630 0.50440 0.45410 0.00500  0.08540  0.04610  284 TYR A OH  
4387 N N   . CYS A 285 ? 0.38110 0.42460 0.33780 0.02840  0.04800  0.01180  285 CYS A N   
4388 C CA  . CYS A 285 ? 0.37680 0.41650 0.33320 0.03090  0.04410  0.00580  285 CYS A CA  
4389 C C   . CYS A 285 ? 0.36630 0.40850 0.33100 0.03390  0.04680  0.00100  285 CYS A C   
4390 O O   . CYS A 285 ? 0.35810 0.40550 0.32170 0.03530  0.05140  -0.00230 285 CYS A O   
4391 C CB  . CYS A 285 ? 0.41000 0.44860 0.35410 0.03140  0.04300  0.00160  285 CYS A CB  
4392 S SG  . CYS A 285 ? 0.44820 0.47920 0.39350 0.03360  0.03920  -0.00570 285 CYS A SG  
4398 N N   . ILE A 286 ? 0.36750 0.40740 0.34040 0.03550  0.04410  0.00080  286 ILE A N   
4399 C CA  . ILE A 286 ? 0.36730 0.41120 0.34800 0.03930  0.04560  -0.00310 286 ILE A CA  
4400 C C   . ILE A 286 ? 0.33070 0.36860 0.30900 0.04350  0.04340  -0.00620 286 ILE A C   
4401 O O   . ILE A 286 ? 0.37050 0.40200 0.34820 0.04300  0.03980  -0.00410 286 ILE A O   
4402 C CB  . ILE A 286 ? 0.38140 0.42830 0.37240 0.03880  0.04430  -0.00140 286 ILE A CB  
4403 C CG1 . ILE A 286 ? 0.39070 0.44070 0.38520 0.03390  0.04720  0.00180  286 ILE A CG1 
4404 C CG2 . ILE A 286 ? 0.36130 0.41490 0.35940 0.04370  0.04480  -0.00600 286 ILE A CG2 
4405 C CD1 . ILE A 286 ? 0.38410 0.43510 0.38860 0.03260  0.04590  0.00240  286 ILE A CD1 
4417 N N   . ASP A 287 ? 0.34830 0.38780 0.32560 0.04770  0.04620  -0.01090 287 ASP A N   
4418 C CA  . ASP A 287 ? 0.38440 0.41620 0.35980 0.05240  0.04530  -0.01370 287 ASP A CA  
4419 C C   . ASP A 287 ? 0.34360 0.38190 0.32620 0.05910  0.04700  -0.01530 287 ASP A C   
4420 O O   . ASP A 287 ? 0.35150 0.39420 0.33410 0.06300  0.05040  -0.01930 287 ASP A O   
4421 C CB  . ASP A 287 ? 0.36870 0.39490 0.33510 0.05250  0.04700  -0.01850 287 ASP A CB  
4422 C CG  . ASP A 287 ? 0.41950 0.43440 0.38480 0.05670  0.04660  -0.02160 287 ASP A CG  
4423 O OD1 . ASP A 287 ? 0.43530 0.44660 0.40610 0.05940  0.04510  -0.01830 287 ASP A OD1 
4424 O OD2 . ASP A 287 ? 0.46160 0.47100 0.42040 0.05750  0.04820  -0.02720 287 ASP A OD2 
4429 N N   . GLY A 288 ? 0.37620 0.41650 0.36470 0.06090  0.04450  -0.01250 288 GLY A N   
4430 C CA  . GLY A 288 ? 0.39440 0.44410 0.38960 0.06750  0.04510  -0.01400 288 GLY A CA  
4431 C C   . GLY A 288 ? 0.36030 0.42400 0.36180 0.06560  0.04740  -0.01690 288 GLY A C   
4432 O O   . GLY A 288 ? 0.36110 0.42910 0.36670 0.05990  0.04670  -0.01570 288 GLY A O   
4436 N N   . ALA A 289 ? 0.34980 0.42040 0.35320 0.07030  0.05060  -0.02070 289 ALA A N   
4437 C CA  . ALA A 289 ? 0.34330 0.42890 0.35450 0.06820  0.05380  -0.02360 289 ALA A CA  
4438 C C   . ALA A 289 ? 0.33160 0.41560 0.33760 0.06190  0.05800  -0.02330 289 ALA A C   
4439 O O   . ALA A 289 ? 0.35950 0.45490 0.37200 0.05830  0.06160  -0.02410 289 ALA A O   
4440 C CB  . ALA A 289 ? 0.34550 0.44200 0.36200 0.07670  0.05580  -0.02760 289 ALA A CB  
4446 N N   . LEU A 290 ? 0.37290 0.44400 0.36750 0.06050  0.05770  -0.02220 290 LEU A N   
4447 C CA  . LEU A 290 ? 0.35100 0.42160 0.33780 0.05660  0.06150  -0.02250 290 LEU A CA  
4448 C C   . LEU A 290 ? 0.34880 0.41640 0.33280 0.04880  0.06030  -0.01710 290 LEU A C   
4449 O O   . LEU A 290 ? 0.37970 0.43990 0.36350 0.04690  0.05560  -0.01390 290 LEU A O   
4450 C CB  . LEU A 290 ? 0.39460 0.45400 0.37000 0.05970  0.06140  -0.02580 290 LEU A CB  
4451 C CG  . LEU A 290 ? 0.46500 0.52160 0.44210 0.06840  0.06210  -0.03030 290 LEU A CG  
4452 C CD1 . LEU A 290 ? 0.57190 0.61430 0.53810 0.06970  0.06190  -0.03420 290 LEU A CD1 
4453 C CD2 . LEU A 290 ? 0.48970 0.56060 0.47250 0.07290  0.06750  -0.03380 290 LEU A CD2 
4465 N N   . LEU A 291 ? 0.36400 0.43720 0.34520 0.04490  0.06500  -0.01550 291 LEU A N   
4466 C CA  . LEU A 291 ? 0.34570 0.41620 0.32440 0.03850  0.06470  -0.00900 291 LEU A CA  
4467 C C   . LEU A 291 ? 0.32870 0.39990 0.29490 0.03710  0.06860  -0.00750 291 LEU A C   
4468 O O   . LEU A 291 ? 0.37170 0.45140 0.33730 0.03850  0.07460  -0.01000 291 LEU A O   
4469 C CB  . LEU A 291 ? 0.37680 0.45500 0.36870 0.03430  0.06740  -0.00640 291 LEU A CB  
4470 C CG  . LEU A 291 ? 0.40980 0.48390 0.40060 0.02810  0.06840  0.00120  291 LEU A CG  
4471 C CD1 . LEU A 291 ? 0.38550 0.44920 0.37370 0.02770  0.06200  0.00440  291 LEU A CD1 
4472 C CD2 . LEU A 291 ? 0.41710 0.49890 0.42300 0.02350  0.07270  0.00210  291 LEU A CD2 
4484 N N   . THR A 292 ? 0.35750 0.42150 0.31370 0.03470  0.06510  -0.00360 292 THR A N   
4485 C CA  . THR A 292 ? 0.36540 0.43130 0.30840 0.03320  0.06800  -0.00050 292 THR A CA  
4486 C C   . THR A 292 ? 0.39550 0.45770 0.33710 0.02910  0.06580  0.00860  292 THR A C   
4487 O O   . THR A 292 ? 0.39240 0.44920 0.34160 0.02800  0.06120  0.01080  292 THR A O   
4488 C CB  . THR A 292 ? 0.39440 0.45630 0.32350 0.03610  0.06510  -0.00670 292 THR A CB  
4489 O OG1 . THR A 292 ? 0.38820 0.44090 0.31720 0.03540  0.05720  -0.00710 292 THR A OG1 
4490 C CG2 . THR A 292 ? 0.43190 0.49570 0.36230 0.04110  0.06810  -0.01550 292 THR A CG2 
4498 N N   . LYS A 293 ? 0.39790 0.46340 0.32890 0.02790  0.06930  0.01420  293 LYS A N   
4499 C CA  . LYS A 293 ? 0.41130 0.47330 0.34000 0.02530  0.06780  0.02410  293 LYS A CA  
4500 C C   . LYS A 293 ? 0.41610 0.47970 0.32620 0.02690  0.06570  0.02650  293 LYS A C   
4501 O O   . LYS A 293 ? 0.44680 0.51580 0.34560 0.02910  0.06820  0.02140  293 LYS A O   
4502 C CB  . LYS A 293 ? 0.45350 0.51800 0.39050 0.02180  0.07560  0.03210  293 LYS A CB  
4503 C CG  . LYS A 293 ? 0.49080 0.56320 0.41820 0.02170  0.08380  0.03590  293 LYS A CG  
4504 C CD  . LYS A 293 ? 0.49770 0.57100 0.43490 0.01710  0.09210  0.04530  293 LYS A CD  
4505 C CE  . LYS A 293 ? 0.56370 0.64440 0.48840 0.01740  0.10070  0.05210  293 LYS A CE  
4506 N NZ  . LYS A 293 ? 0.74440 0.82310 0.67830 0.01240  0.10890  0.06350  293 LYS A NZ  
4520 N N   . SER A 294 ? 0.43890 0.49900 0.34580 0.02640  0.06120  0.03410  294 SER A N   
4521 C CA  . SER A 294 ? 0.45030 0.51420 0.33970 0.02840  0.05820  0.03740  294 SER A CA  
4522 C C   . SER A 294 ? 0.46010 0.52100 0.35000 0.02830  0.05550  0.04910  294 SER A C   
4523 O O   . SER A 294 ? 0.47830 0.53260 0.38190 0.02700  0.05380  0.05180  294 SER A O   
4524 C CB  . SER A 294 ? 0.46800 0.53200 0.35030 0.02980  0.05020  0.02690  294 SER A CB  
4525 O OG  . SER A 294 ? 0.48910 0.54710 0.38160 0.02870  0.04310  0.02590  294 SER A OG  
4531 N N   . SER A 295 ? 0.44790 0.51410 0.32220 0.03070  0.05530  0.05610  295 SER A N   
4532 C CA  . SER A 295 ? 0.46990 0.53350 0.34390 0.03220  0.05270  0.06820  295 SER A CA  
4533 C C   . SER A 295 ? 0.51760 0.58210 0.39120 0.03370  0.04150  0.06490  295 SER A C   
4534 O O   . SER A 295 ? 0.54160 0.60200 0.42290 0.03470  0.03840  0.07200  295 SER A O   
4535 C CB  . SER A 295 ? 0.52390 0.59380 0.38130 0.03510  0.05730  0.07910  295 SER A CB  
4536 O OG  . SER A 295 ? 0.63440 0.71420 0.47390 0.03750  0.05420  0.07210  295 SER A OG  
4542 N N   . GLU A 296 ? 0.51610 0.58580 0.38250 0.03370  0.03580  0.05360  296 GLU A N   
4543 C CA  . GLU A 296 ? 0.54260 0.61450 0.41030 0.03380  0.02550  0.04860  296 GLU A CA  
4544 C C   . GLU A 296 ? 0.51400 0.58140 0.39020 0.03080  0.02360  0.03530  296 GLU A C   
4545 O O   . GLU A 296 ? 0.51020 0.57510 0.38670 0.03010  0.02930  0.02930  296 GLU A O   
4546 C CB  . GLU A 296 ? 0.59950 0.68290 0.44900 0.03650  0.01970  0.04810  296 GLU A CB  
4547 C CG  . GLU A 296 ? 0.70130 0.78960 0.54220 0.04080  0.02030  0.06320  296 GLU A CG  
4548 C CD  . GLU A 296 ? 1.04340 1.14570 0.86470 0.04440  0.01390  0.06250  296 GLU A CD  
4549 O OE1 . GLU A 296 ? 1.08210 1.18990 0.89390 0.04930  0.01400  0.07540  296 GLU A OE1 
4550 O OE2 . GLU A 296 ? 1.07700 1.18460 0.89220 0.04270  0.00870  0.04880  296 GLU A OE2 
4557 N N   . TYR A 297 ? 0.48620 0.55270 0.37040 0.02950  0.01610  0.03140  297 TYR A N   
4558 C CA  . TYR A 297 ? 0.46110 0.52180 0.35390 0.02690  0.01490  0.02050  297 TYR A CA  
4559 C C   . TYR A 297 ? 0.49990 0.56390 0.39480 0.02490  0.00600  0.01520  297 TYR A C   
4560 O O   . TYR A 297 ? 0.55490 0.62230 0.45560 0.02530  0.00130  0.02150  297 TYR A O   
4561 C CB  . TYR A 297 ? 0.46870 0.52110 0.37740 0.02630  0.01870  0.02260  297 TYR A CB  
4562 C CG  . TYR A 297 ? 0.47040 0.51680 0.38480 0.02520  0.02010  0.01270  297 TYR A CG  
4563 C CD1 . TYR A 297 ? 0.47140 0.51470 0.39230 0.02340  0.01510  0.00720  297 TYR A CD1 
4564 C CD2 . TYR A 297 ? 0.55240 0.59680 0.46620 0.02640  0.02690  0.00950  297 TYR A CD2 
4565 C CE1 . TYR A 297 ? 0.45200 0.48820 0.37760 0.02320  0.01710  -0.00050 297 TYR A CE1 
4566 C CE2 . TYR A 297 ? 0.54630 0.58540 0.46480 0.02680  0.02820  0.00120  297 TYR A CE2 
4567 C CZ  . TYR A 297 ? 0.51500 0.54910 0.43890 0.02550  0.02340  -0.00330 297 TYR A CZ  
4568 O OH  . TYR A 297 ? 0.54960 0.57680 0.47790 0.02670  0.02550  -0.01010 297 TYR A OH  
4578 N N   . LYS A 298 ? 0.52330 0.58610 0.41450 0.02280  0.00390  0.00340  298 LYS A N   
4579 C CA  . LYS A 298 ? 0.49750 0.56190 0.39360 0.01920  -0.00380 -0.00380 298 LYS A CA  
4580 C C   . LYS A 298 ? 0.50420 0.55740 0.40760 0.01690  -0.00120 -0.01330 298 LYS A C   
4581 O O   . LYS A 298 ? 0.52540 0.57400 0.42240 0.01840  0.00390  -0.01900 298 LYS A O   
4582 C CB  . LYS A 298 ? 0.52720 0.60230 0.40950 0.01850  -0.01050 -0.01000 298 LYS A CB  
4583 C CG  . LYS A 298 ? 0.79320 0.88130 0.66690 0.02180  -0.01440 -0.00020 298 LYS A CG  
4584 C CD  . LYS A 298 ? 0.98000 1.08140 0.84640 0.02020  -0.02460 -0.00730 298 LYS A CD  
4585 C CE  . LYS A 298 ? 1.05960 1.17520 0.91590 0.02520  -0.02870 0.00380  298 LYS A CE  
4586 N NZ  . LYS A 298 ? 1.14910 1.27510 1.01600 0.02450  -0.03780 0.00690  298 LYS A NZ  
4600 N N   . GLY A 299 ? 0.50280 0.55190 0.41990 0.01390  -0.00400 -0.01430 299 GLY A N   
4601 C CA  . GLY A 299 ? 0.49070 0.52830 0.41500 0.01210  -0.00130 -0.02170 299 GLY A CA  
4602 C C   . GLY A 299 ? 0.42870 0.46400 0.36780 0.00840  -0.00450 -0.02060 299 GLY A C   
4603 O O   . GLY A 299 ? 0.43030 0.47420 0.37490 0.00740  -0.00890 -0.01450 299 GLY A O   
4607 N N   . PRO A 300 ? 0.46460 0.48860 0.41100 0.00670  -0.00190 -0.02580 300 PRO A N   
4608 C CA  . PRO A 300 ? 0.40550 0.42640 0.36680 0.00290  -0.00340 -0.02400 300 PRO A CA  
4609 C C   . PRO A 300 ? 0.40250 0.42300 0.37220 0.00660  0.00040  -0.01350 300 PRO A C   
4610 O O   . PRO A 300 ? 0.45450 0.46600 0.42830 0.00940  0.00570  -0.01200 300 PRO A O   
4611 C CB  . PRO A 300 ? 0.42480 0.43160 0.38850 0.00090  -0.00040 -0.03270 300 PRO A CB  
4612 C CG  . PRO A 300 ? 0.46990 0.47130 0.42310 0.00670  0.00490  -0.03500 300 PRO A CG  
4613 C CD  . PRO A 300 ? 0.45350 0.46670 0.39460 0.00890  0.00320  -0.03310 300 PRO A CD  
4621 N N   . ILE A 301 ? 0.41360 0.44460 0.38540 0.00740  -0.00260 -0.00630 301 ILE A N   
4622 C CA  . ILE A 301 ? 0.36480 0.39630 0.34370 0.01110  0.00050  0.00260  301 ILE A CA  
4623 C C   . ILE A 301 ? 0.38340 0.41480 0.37600 0.00870  0.00010  0.00490  301 ILE A C   
4624 O O   . ILE A 301 ? 0.35900 0.39580 0.35730 0.00370  -0.00440 0.00260  301 ILE A O   
4625 C CB  . ILE A 301 ? 0.36300 0.40410 0.33860 0.01380  -0.00170 0.00950  301 ILE A CB  
4626 C CG1 . ILE A 301 ? 0.37710 0.41900 0.33890 0.01580  -0.00060 0.00830  301 ILE A CG1 
4627 C CG2 . ILE A 301 ? 0.38480 0.42480 0.36730 0.01790  0.00190  0.01700  301 ILE A CG2 
4628 C CD1 . ILE A 301 ? 0.43240 0.46560 0.39060 0.01790  0.00570  0.00510  301 ILE A CD1 
4640 N N   . THR A 302 ? 0.38020 0.40680 0.37810 0.01220  0.00500  0.00950  302 THR A N   
4641 C CA  . THR A 302 ? 0.38210 0.40920 0.39220 0.01090  0.00610  0.01320  302 THR A CA  
4642 C C   . THR A 302 ? 0.35860 0.39110 0.37350 0.01560  0.00790  0.02080  302 THR A C   
4643 O O   . THR A 302 ? 0.33290 0.37070 0.35790 0.01440  0.00770  0.02450  302 THR A O   
4644 C CB  . THR A 302 ? 0.42570 0.44060 0.43800 0.01080  0.01100  0.01100  302 THR A CB  
4645 O OG1 . THR A 302 ? 0.45950 0.47490 0.48370 0.00770  0.01220  0.01430  302 THR A OG1 
4646 C CG2 . THR A 302 ? 0.33650 0.34650 0.34370 0.01770  0.01570  0.01320  302 THR A CG2 
4654 N N   . ASP A 303 ? 0.33790 0.37010 0.34690 0.02050  0.00960  0.02280  303 ASP A N   
4655 C CA  . ASP A 303 ? 0.32380 0.36020 0.33700 0.02500  0.01100  0.02840  303 ASP A CA  
4656 C C   . ASP A 303 ? 0.34980 0.38810 0.35710 0.02730  0.01020  0.02990  303 ASP A C   
4657 O O   . ASP A 303 ? 0.37670 0.41090 0.37620 0.02740  0.01150  0.02710  303 ASP A O   
4658 C CB  . ASP A 303 ? 0.34480 0.37640 0.35950 0.02940  0.01610  0.02920  303 ASP A CB  
4659 C CG  . ASP A 303 ? 0.32930 0.35610 0.34780 0.02790  0.01860  0.02880  303 ASP A CG  
4660 O OD1 . ASP A 303 ? 0.35660 0.38740 0.38340 0.02640  0.01890  0.03220  303 ASP A OD1 
4661 O OD2 . ASP A 303 ? 0.38280 0.40200 0.39670 0.02860  0.02070  0.02560  303 ASP A OD2 
4667 N N   . VAL A 304 ? 0.35640 0.40050 0.36790 0.02950  0.00860  0.03480  304 VAL A N   
4668 C CA  . VAL A 304 ? 0.33090 0.37480 0.33820 0.03200  0.00870  0.03770  304 VAL A CA  
4669 C C   . VAL A 304 ? 0.35020 0.39400 0.36410 0.03670  0.01100  0.04120  304 VAL A C   
4670 O O   . VAL A 304 ? 0.35550 0.40450 0.37710 0.03820  0.01020  0.04350  304 VAL A O   
4671 C CB  . VAL A 304 ? 0.32990 0.38030 0.33360 0.03090  0.00390  0.04060  304 VAL A CB  
4672 C CG1 . VAL A 304 ? 0.38310 0.43080 0.38130 0.03380  0.00540  0.04490  304 VAL A CG1 
4673 C CG2 . VAL A 304 ? 0.37050 0.42210 0.36740 0.02630  0.00100  0.03540  304 VAL A CG2 
4683 N N   . PHE A 305 ? 0.33660 0.37500 0.34820 0.03870  0.01410  0.04080  305 PHE A N   
4684 C CA  . PHE A 305 ? 0.35730 0.39390 0.37450 0.04290  0.01640  0.04210  305 PHE A CA  
4685 C C   . PHE A 305 ? 0.36650 0.40070 0.38320 0.04450  0.01620  0.04690  305 PHE A C   
4686 O O   . PHE A 305 ? 0.37930 0.41100 0.38970 0.04230  0.01650  0.04820  305 PHE A O   
4687 C CB  . PHE A 305 ? 0.33550 0.36780 0.35230 0.04370  0.02000  0.03690  305 PHE A CB  
4688 C CG  . PHE A 305 ? 0.34980 0.38410 0.36690 0.04400  0.02060  0.03390  305 PHE A CG  
4689 C CD1 . PHE A 305 ? 0.36780 0.40090 0.38030 0.04100  0.02020  0.03180  305 PHE A CD1 
4690 C CD2 . PHE A 305 ? 0.37170 0.40850 0.39320 0.04790  0.02210  0.03360  305 PHE A CD2 
4691 C CE1 . PHE A 305 ? 0.36270 0.39560 0.37570 0.04180  0.02140  0.03020  305 PHE A CE1 
4692 C CE2 . PHE A 305 ? 0.37800 0.41630 0.39910 0.04880  0.02340  0.03260  305 PHE A CE2 
4693 C CZ  . PHE A 305 ? 0.34990 0.38550 0.36720 0.04570  0.02310  0.03140  305 PHE A CZ  
4703 N N   . TYR A 306 ? 0.35160 0.38680 0.37480 0.04880  0.01620  0.05010  306 TYR A N   
4704 C CA  . TYR A 306 ? 0.39670 0.42810 0.42070 0.05160  0.01650  0.05580  306 TYR A CA  
4705 C C   . TYR A 306 ? 0.38000 0.40490 0.41060 0.05570  0.02010  0.05410  306 TYR A C   
4706 O O   . TYR A 306 ? 0.38410 0.41190 0.41950 0.05810  0.02090  0.05030  306 TYR A O   
4707 C CB  . TYR A 306 ? 0.40520 0.44500 0.43150 0.05440  0.01230  0.06210  306 TYR A CB  
4708 C CG  . TYR A 306 ? 0.37000 0.41810 0.39070 0.05040  0.00770  0.06250  306 TYR A CG  
4709 C CD1 . TYR A 306 ? 0.35190 0.40680 0.37530 0.04710  0.00560  0.05830  306 TYR A CD1 
4710 C CD2 . TYR A 306 ? 0.40780 0.45680 0.42060 0.05000  0.00550  0.06700  306 TYR A CD2 
4711 C CE1 . TYR A 306 ? 0.35890 0.42070 0.37820 0.04290  0.00110  0.05710  306 TYR A CE1 
4712 C CE2 . TYR A 306 ? 0.42560 0.48300 0.43260 0.04670  0.00070  0.06590  306 TYR A CE2 
4713 C CZ  . TYR A 306 ? 0.39960 0.46310 0.41030 0.04280  -0.00170 0.06020  306 TYR A CZ  
4714 O OH  . TYR A 306 ? 0.38520 0.45630 0.39050 0.03890  -0.00670 0.05780  306 TYR A OH  
4724 N N   . LYS A 307 ? 0.46660 0.48250 0.49740 0.05650  0.02250  0.05700  307 LYS A N   
4725 C CA  . LYS A 307 ? 0.43800 0.44590 0.47590 0.06050  0.02570  0.05520  307 LYS A CA  
4726 C C   . LYS A 307 ? 0.44800 0.45930 0.49140 0.06730  0.02420  0.06030  307 LYS A C   
4727 O O   . LYS A 307 ? 0.44900 0.46610 0.49080 0.06900  0.02110  0.06770  307 LYS A O   
4728 C CB  . LYS A 307 ? 0.53690 0.53250 0.57490 0.05870  0.02940  0.05780  307 LYS A CB  
4729 C CG  . LYS A 307 ? 0.71500 0.70660 0.75140 0.05230  0.03240  0.05200  307 LYS A CG  
4730 C CD  . LYS A 307 ? 0.93400 0.92190 0.97730 0.05190  0.03460  0.04180  307 LYS A CD  
4731 C CE  . LYS A 307 ? 0.98620 0.98070 1.02700 0.04750  0.03430  0.03400  307 LYS A CE  
4732 N NZ  . LYS A 307 ? 0.57190 0.57660 0.60970 0.04980  0.03130  0.03020  307 LYS A NZ  
4746 N N   . GLU A 308 ? 0.41750 0.42620 0.46750 0.07180  0.02650  0.05590  308 GLU A N   
4747 C CA  . GLU A 308 ? 0.39520 0.40660 0.45160 0.07940  0.02610  0.06010  308 GLU A CA  
4748 C C   . GLU A 308 ? 0.41720 0.41830 0.47940 0.08370  0.03030  0.05420  308 GLU A C   
4749 O O   . GLU A 308 ? 0.42530 0.42020 0.48660 0.08020  0.03250  0.04590  308 GLU A O   
4750 C CB  . GLU A 308 ? 0.42010 0.44720 0.47870 0.08080  0.02350  0.06010  308 GLU A CB  
4751 C CG  . GLU A 308 ? 0.41080 0.44530 0.47730 0.08860  0.02280  0.06480  308 GLU A CG  
4752 C CD  . GLU A 308 ? 0.43540 0.46900 0.50260 0.09200  0.02040  0.07430  308 GLU A CD  
4753 O OE1 . GLU A 308 ? 0.44420 0.46490 0.51310 0.09650  0.02320  0.07660  308 GLU A OE1 
4754 O OE2 . GLU A 308 ? 0.45490 0.50060 0.52100 0.09040  0.01570  0.07930  308 GLU A OE2 
4761 N N   A ASN A 309 ? 0.43800 0.43670 0.50630 0.09150  0.03120  0.05830  309 ASN A N   
4762 N N   B ASN A 309 ? 0.43780 0.43780 0.50630 0.09160  0.03110  0.05780  309 ASN A N   
4763 C CA  A ASN A 309 ? 0.46080 0.45130 0.53540 0.09730  0.03490  0.05180  309 ASN A CA  
4764 C CA  B ASN A 309 ? 0.45810 0.45030 0.53260 0.09740  0.03490  0.05090  309 ASN A CA  
4765 C C   A ASN A 309 ? 0.45970 0.46120 0.54000 0.10610  0.03440  0.05510  309 ASN A C   
4766 C C   B ASN A 309 ? 0.45950 0.46120 0.54010 0.10650  0.03450  0.05480  309 ASN A C   
4767 O O   A ASN A 309 ? 0.44860 0.46040 0.53030 0.10820  0.03500  0.04950  309 ASN A O   
4768 O O   B ASN A 309 ? 0.44890 0.46050 0.53140 0.10940  0.03540  0.04940  309 ASN A O   
4769 C CB  A ASN A 309 ? 0.47990 0.45080 0.55780 0.09850  0.03840  0.05360  309 ASN A CB  
4770 C CB  B ASN A 309 ? 0.47610 0.44850 0.55330 0.09730  0.03830  0.05110  309 ASN A CB  
4771 C CG  A ASN A 309 ? 0.49060 0.45820 0.56660 0.09930  0.03720  0.06690  309 ASN A CG  
4772 C CG  B ASN A 309 ? 0.49260 0.45520 0.57680 0.10340  0.04220  0.04280  309 ASN A CG  
4773 O OD1 A ASN A 309 ? 0.48810 0.46470 0.56560 0.10560  0.03450  0.07520  309 ASN A OD1 
4774 O OD1 B ASN A 309 ? 0.52850 0.50020 0.61470 0.10910  0.04240  0.03780  309 ASN A OD1 
4775 N ND2 A ASN A 309 ? 0.52550 0.48110 0.59840 0.09340  0.03930  0.06930  309 ASN A ND2 
4776 N ND2 B ASN A 309 ? 0.54870 0.49230 0.63680 0.10200  0.04570  0.04110  309 ASN A ND2 
4789 N N   . SER A 310 ? 0.46040 0.46130 0.54420 0.11150  0.03320  0.06490  310 SER A N   
4790 C CA  . SER A 310 ? 0.47570 0.48850 0.56680 0.12050  0.03240  0.06940  310 SER A CA  
4791 C C   . SER A 310 ? 0.49150 0.51250 0.58230 0.12170  0.02770  0.08150  310 SER A C   
4792 O O   . SER A 310 ? 0.51470 0.52430 0.60270 0.12240  0.02770  0.08840  310 SER A O   
4793 C CB  . SER A 310 ? 0.51740 0.51810 0.61560 0.13020  0.03700  0.06690  310 SER A CB  
4794 O OG  . SER A 310 ? 0.59820 0.61250 0.70430 0.13970  0.03680  0.07060  310 SER A OG  
4801 N N   . TYR A 311 ? 0.47790 0.51940 0.57190 0.12190  0.02390  0.08420  311 TYR A N   
4802 C CA  . TYR A 311 ? 0.46820 0.52210 0.56290 0.12340  0.01830  0.09410  311 TYR A CA  
4803 C C   . TYR A 311 ? 0.48870 0.56050 0.59530 0.13160  0.01720  0.09690  311 TYR A C   
4804 O O   . TYR A 311 ? 0.45960 0.54170 0.57140 0.13100  0.01920  0.09120  311 TYR A O   
4805 C CB  . TYR A 311 ? 0.43070 0.49430 0.51820 0.11280  0.01350  0.09340  311 TYR A CB  
4806 C CG  . TYR A 311 ? 0.43050 0.51190 0.51990 0.11390  0.00670  0.10100  311 TYR A CG  
4807 C CD1 . TYR A 311 ? 0.43900 0.51730 0.52180 0.11580  0.00340  0.10930  311 TYR A CD1 
4808 C CD2 . TYR A 311 ? 0.41020 0.51260 0.50840 0.11300  0.00360  0.10000  311 TYR A CD2 
4809 C CE1 . TYR A 311 ? 0.45400 0.55060 0.53780 0.11730  -0.00370 0.11540  311 TYR A CE1 
4810 C CE2 . TYR A 311 ? 0.39260 0.51340 0.49400 0.11340  -0.00350 0.10560  311 TYR A CE2 
4811 C CZ  . TYR A 311 ? 0.44060 0.55880 0.53410 0.11590  -0.00760 0.11300  311 TYR A CZ  
4812 O OH  . TYR A 311 ? 0.43090 0.56920 0.52650 0.11700  -0.01560 0.11790  311 TYR A OH  
4822 N N   . THR A 312 ? 0.44880 0.52500 0.55970 0.14000  0.01450  0.10620  312 THR A N   
4823 C CA  . THR A 312 ? 0.46250 0.56010 0.58570 0.14780  0.01200  0.11030  312 THR A CA  
4824 C C   . THR A 312 ? 0.47670 0.58960 0.59920 0.14800  0.00400  0.11940  312 THR A C   
4825 O O   . THR A 312 ? 0.51020 0.61280 0.62510 0.15070  0.00230  0.12670  312 THR A O   
4826 C CB  . THR A 312 ? 0.48110 0.57140 0.61280 0.16150  0.01680  0.11230  312 THR A CB  
4827 O OG1 . THR A 312 ? 0.56550 0.64060 0.69620 0.16120  0.02390  0.10230  312 THR A OG1 
4828 C CG2 . THR A 312 ? 0.50810 0.62350 0.65400 0.16950  0.01480  0.11570  312 THR A CG2 
4836 N N   . THR A 313 ? 0.43710 0.57500 0.56750 0.14510  -0.00080 0.11910  313 THR A N   
4837 C CA  . THR A 313 ? 0.45700 0.61310 0.58740 0.14450  -0.00960 0.12560  313 THR A CA  
4838 C C   . THR A 313 ? 0.49800 0.65930 0.63400 0.15880  -0.01190 0.13610  313 THR A C   
4839 O O   . THR A 313 ? 0.48640 0.64190 0.63040 0.16960  -0.00670 0.13770  313 THR A O   
4840 C CB  . THR A 313 ? 0.44150 0.62430 0.58290 0.13800  -0.01390 0.12180  313 THR A CB  
4841 O OG1 . THR A 313 ? 0.47330 0.67230 0.61210 0.13430  -0.02330 0.12520  313 THR A OG1 
4842 C CG2 . THR A 313 ? 0.44780 0.64830 0.60730 0.14750  -0.01210 0.12370  313 THR A CG2 
4850 N N   . THR A 314 ? 0.54280 0.71580 0.67390 0.15950  -0.02000 0.14310  314 THR A N   
4851 C CA  . THR A 314 ? 0.50440 0.68980 0.64160 0.17330  -0.02430 0.15400  314 THR A CA  
4852 C C   . THR A 314 ? 0.57350 0.79440 0.72330 0.17320  -0.03300 0.15430  314 THR A C   
4853 O O   . THR A 314 ? 0.56060 0.79730 0.71900 0.18550  -0.03700 0.16260  314 THR A O   
4854 C CB  . THR A 314 ? 0.50730 0.68060 0.62870 0.17670  -0.02690 0.16370  314 THR A CB  
4855 O OG1 . THR A 314 ? 0.54040 0.72630 0.65180 0.16640  -0.03450 0.16160  314 THR A OG1 
4856 C CG2 . THR A 314 ? 0.61110 0.74970 0.72200 0.17510  -0.01790 0.16300  314 THR A CG2 
4864 N N   . ILE A 315 ? 0.52050 0.75460 0.67270 0.15960  -0.03600 0.14550  315 ILE A N   
4865 C CA  . ILE A 315 ? 0.51860 0.78660 0.68600 0.15720  -0.04350 0.14380  315 ILE A CA  
4866 C C   . ILE A 315 ? 0.56250 0.84460 0.75000 0.16790  -0.03990 0.14610  315 ILE A C   
4867 O O   . ILE A 315 ? 0.51020 0.78400 0.70390 0.16690  -0.03120 0.14090  315 ILE A O   
4868 C CB  . ILE A 315 ? 0.49430 0.76730 0.66250 0.14000  -0.04410 0.13290  315 ILE A CB  
4869 C CG1 . ILE A 315 ? 0.52100 0.78310 0.66980 0.13070  -0.04850 0.13050  315 ILE A CG1 
4870 C CG2 . ILE A 315 ? 0.51620 0.82330 0.70400 0.13620  -0.05030 0.13030  315 ILE A CG2 
4871 C CD1 . ILE A 315 ? 0.48940 0.75200 0.63760 0.11450  -0.04860 0.11970  315 ILE A CD1 
4883 N N   . LYS A 316 ? 0.67510 0.97980 0.87230 0.17930  -0.04650 0.15400  316 LYS A N   
4884 C CA  . LYS A 316 ? 0.68700 1.01030 0.90530 0.19010  -0.04390 0.15630  316 LYS A CA  
4885 C C   . LYS A 316 ? 0.71550 1.07460 0.95180 0.18130  -0.05020 0.15130  316 LYS A C   
4886 O O   . LYS A 316 ? 0.75800 1.14370 1.00040 0.18400  -0.06070 0.15520  316 LYS A O   
4887 C CB  . LYS A 316 ? 0.55860 0.88620 0.77900 0.20900  -0.04690 0.16840  316 LYS A CB  
4890 N N   . PRO A 317 ? 0.61730 0.97920 0.86280 0.17070  -0.04410 0.14300  317 PRO A N   
4891 C CA  . PRO A 317 ? 0.69460 1.08850 0.95720 0.15980  -0.05000 0.13810  317 PRO A CA  
4892 C C   . PRO A 317 ? 0.67460 1.09500 0.96320 0.16600  -0.04610 0.13920  317 PRO A C   
4893 O O   . PRO A 317 ? 0.59690 1.04730 0.90070 0.17330  -0.05370 0.14370  317 PRO A O   
4894 C CB  . PRO A 317 ? 0.64060 1.01790 0.89480 0.14230  -0.04560 0.12900  317 PRO A CB  
# 
