data_9F6V
# 
_entry.id   9F6V 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9F6V         pdb_00009f6v 10.2210/pdb9f6v/pdb 
WWPDB D_1292138324 ?            ?                   
EMDB  EMD-50241    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-02 ? 
2 'Structure model' 1 1 2025-05-14 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 2 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.page_first'     
3 2 'Structure model' '_em_admin.last_update'    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9F6V 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'cryoEM structure of Asgard tubulin heterodimer AtubA/B2 with GTP' 
_pdbx_database_related.db_id          EMD-50241 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              pilhofer@mol.biol.ethz.ch 
_pdbx_contact_author.name_first         Martin 
_pdbx_contact_author.name_last          Pilhofer 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3649-3340 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wollweber, F.'          1 ? 
'Xu, J.'                 2 ? 
'Ponce-Toled, R.I.'      3 ? 
'Rodrigues-Oliveira, T.' 4 ? 
'Malit, J.J.L.'          5 ? 
'Kokhanovska, A.'        6 ? 
'Schleper, C.'           7 ? 
'Pilhofer, M.'           8 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Cell 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1097-4172 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            188 
_citation.language                  ? 
_citation.page_first                2451 
_citation.page_last                 ? 
_citation.title                     'Microtubules in Asgard archaea.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.cell.2025.02.027 
_citation.pdbx_database_id_PubMed   40120574 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wollweber, F.'          1  ? 
primary 'Xu, J.'                 2  ? 
primary 'Ponce-Toledo, R.I.'     3  ? 
primary 'Marxer, F.'             4  ? 
primary 'Rodrigues-Oliveira, T.' 5  ? 
primary 'Possnecker, A.'         6  ? 
primary 'Luo, Z.H.'              7  ? 
primary 'Malit, J.J.L.'          8  ? 
primary 'Kokhanovska, A.'        9  ? 
primary 'Wieczorek, M.'          10 ? 
primary 'Schleper, C.'           11 ? 
primary 'Pilhofer, M.'           12 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Asgard tubulin A (AtubA) from Candidatus Lokiarchaeum ossiferum'          46040.281 1 ? ? ? ? 
2 polymer     man 'Asgard tubulin B homolog (AtubB2) from Candidatus Lokiarchaeum ossiferum' 47882.949 1 ? ? ? ? 
3 non-polymer syn "GUANOSINE-5'-TRIPHOSPHATE"                                                523.180   1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MAGEIVCIQVGQAGNQIAGAFWQKICAEHGIDPVNGKAIDVVGDTDIFFNTIGDKYIPRAVVVDLEPAVVENIREKFGTL
FDPKSIVSGADGAGNNFAIGFNEHGAETLEKVMQVVEQRVSETESIGGFILTHSCGGGTGSGFGSKILKTIRERYPKVPI
FTFSIFPSPKISETVVEPYNAIMTLSNLIKYASCSIVLDNEALFSIAEKKLEVENPSLEDLNLIIAQVLTNVTASLRFSG
TLNLDLGKLVTNLVPFSNLHFLMASTAPLVLAGKESYEKMTAKELSAQVFGDEYICAACKPTTGRYLAASVLFRGAVKTS
DVNEAMATVKEQNSFVNWIPTGFKISKSETSPKDSALGVIMLGNNSEIVSVFERIGANFDRLWSRKAFAHWFTDSGFEEK
DLDDARALVQKVIDDYRKLTEDA
;
;MAGEIVCIQVGQAGNQIAGAFWQKICAEHGIDPVNGKAIDVVGDTDIFFNTIGDKYIPRAVVVDLEPAVVENIREKFGTL
FDPKSIVSGADGAGNNFAIGFNEHGAETLEKVMQVVEQRVSETESIGGFILTHSCGGGTGSGFGSKILKTIRERYPKVPI
FTFSIFPSPKISETVVEPYNAIMTLSNLIKYASCSIVLDNEALFSIAEKKLEVENPSLEDLNLIIAQVLTNVTASLRFSG
TLNLDLGKLVTNLVPFSNLHFLMASTAPLVLAGKESYEKMTAKELSAQVFGDEYICAACKPTTGRYLAASVLFRGAVKTS
DVNEAMATVKEQNSFVNWIPTGFKISKSETSPKDSALGVIMLGNNSEIVSVFERIGANFDRLWSRKAFAHWFTDSGFEEK
DLDDARALVQKVIDDYRKLTEDA
;
A ? 
2 'polypeptide(L)' no no 
;MAREVITIHVGELGIQIAPNFWKYLCDEHNIDYKGQEKGKIRGVIDNFFEKASIGKWIPRTILVDLGPNAIRKVTKKDMK
DFFDPKRCVMGLAGDANLFAKGYYSYGTRFMEEIMDKIQKEVDQTEHLQGFIVVHSIGDGTGAGLAPLIMEAIKKKHPKL
VMMSYSIVPSQNMDCSTILPYNAILSLDKLTSCADISMIIDNDSIYRIVATQGKENELSESIFDQVLAKALVEITATLRF
NSPLNRSMMEMSTNLVPFPRNHFLMTSMSPLETSLTSAHQKIETKELMQDLIDQDHILAPITVEKGVFTAFVIALRGENP
HSILQNSIKGFGDRVKFSEIFPTAIKADSTTLTDEKLARSGITLMNHSGVANLFQFLLTQFELMYDHDAFTTWYYQEGMQ
PSEFEAAKNNIQKLITEYKQDEY
;
;MAREVITIHVGELGIQIAPNFWKYLCDEHNIDYKGQEKGKIRGVIDNFFEKASIGKWIPRTILVDLGPNAIRKVTKKDMK
DFFDPKRCVMGLAGDANLFAKGYYSYGTRFMEEIMDKIQKEVDQTEHLQGFIVVHSIGDGTGAGLAPLIMEAIKKKHPKL
VMMSYSIVPSQNMDCSTILPYNAILSLDKLTSCADISMIIDNDSIYRIVATQGKENELSESIFDQVLAKALVEITATLRF
NSPLNRSMMEMSTNLVPFPRNHFLMTSMSPLETSLTSAHQKIETKELMQDLIDQDHILAPITVEKGVFTAFVIALRGENP
HSILQNSIKGFGDRVKFSEIFPTAIKADSTTLTDEKLARSGITLMNHSGVANLFQFLLTQFELMYDHDAFTTWYYQEGMQ
PSEFEAAKNNIQKLITEYKQDEY
;
D ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        "GUANOSINE-5'-TRIPHOSPHATE" 
_pdbx_entity_nonpoly.comp_id     GTP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   GLY n 
1 4   GLU n 
1 5   ILE n 
1 6   VAL n 
1 7   CYS n 
1 8   ILE n 
1 9   GLN n 
1 10  VAL n 
1 11  GLY n 
1 12  GLN n 
1 13  ALA n 
1 14  GLY n 
1 15  ASN n 
1 16  GLN n 
1 17  ILE n 
1 18  ALA n 
1 19  GLY n 
1 20  ALA n 
1 21  PHE n 
1 22  TRP n 
1 23  GLN n 
1 24  LYS n 
1 25  ILE n 
1 26  CYS n 
1 27  ALA n 
1 28  GLU n 
1 29  HIS n 
1 30  GLY n 
1 31  ILE n 
1 32  ASP n 
1 33  PRO n 
1 34  VAL n 
1 35  ASN n 
1 36  GLY n 
1 37  LYS n 
1 38  ALA n 
1 39  ILE n 
1 40  ASP n 
1 41  VAL n 
1 42  VAL n 
1 43  GLY n 
1 44  ASP n 
1 45  THR n 
1 46  ASP n 
1 47  ILE n 
1 48  PHE n 
1 49  PHE n 
1 50  ASN n 
1 51  THR n 
1 52  ILE n 
1 53  GLY n 
1 54  ASP n 
1 55  LYS n 
1 56  TYR n 
1 57  ILE n 
1 58  PRO n 
1 59  ARG n 
1 60  ALA n 
1 61  VAL n 
1 62  VAL n 
1 63  VAL n 
1 64  ASP n 
1 65  LEU n 
1 66  GLU n 
1 67  PRO n 
1 68  ALA n 
1 69  VAL n 
1 70  VAL n 
1 71  GLU n 
1 72  ASN n 
1 73  ILE n 
1 74  ARG n 
1 75  GLU n 
1 76  LYS n 
1 77  PHE n 
1 78  GLY n 
1 79  THR n 
1 80  LEU n 
1 81  PHE n 
1 82  ASP n 
1 83  PRO n 
1 84  LYS n 
1 85  SER n 
1 86  ILE n 
1 87  VAL n 
1 88  SER n 
1 89  GLY n 
1 90  ALA n 
1 91  ASP n 
1 92  GLY n 
1 93  ALA n 
1 94  GLY n 
1 95  ASN n 
1 96  ASN n 
1 97  PHE n 
1 98  ALA n 
1 99  ILE n 
1 100 GLY n 
1 101 PHE n 
1 102 ASN n 
1 103 GLU n 
1 104 HIS n 
1 105 GLY n 
1 106 ALA n 
1 107 GLU n 
1 108 THR n 
1 109 LEU n 
1 110 GLU n 
1 111 LYS n 
1 112 VAL n 
1 113 MET n 
1 114 GLN n 
1 115 VAL n 
1 116 VAL n 
1 117 GLU n 
1 118 GLN n 
1 119 ARG n 
1 120 VAL n 
1 121 SER n 
1 122 GLU n 
1 123 THR n 
1 124 GLU n 
1 125 SER n 
1 126 ILE n 
1 127 GLY n 
1 128 GLY n 
1 129 PHE n 
1 130 ILE n 
1 131 LEU n 
1 132 THR n 
1 133 HIS n 
1 134 SER n 
1 135 CYS n 
1 136 GLY n 
1 137 GLY n 
1 138 GLY n 
1 139 THR n 
1 140 GLY n 
1 141 SER n 
1 142 GLY n 
1 143 PHE n 
1 144 GLY n 
1 145 SER n 
1 146 LYS n 
1 147 ILE n 
1 148 LEU n 
1 149 LYS n 
1 150 THR n 
1 151 ILE n 
1 152 ARG n 
1 153 GLU n 
1 154 ARG n 
1 155 TYR n 
1 156 PRO n 
1 157 LYS n 
1 158 VAL n 
1 159 PRO n 
1 160 ILE n 
1 161 PHE n 
1 162 THR n 
1 163 PHE n 
1 164 SER n 
1 165 ILE n 
1 166 PHE n 
1 167 PRO n 
1 168 SER n 
1 169 PRO n 
1 170 LYS n 
1 171 ILE n 
1 172 SER n 
1 173 GLU n 
1 174 THR n 
1 175 VAL n 
1 176 VAL n 
1 177 GLU n 
1 178 PRO n 
1 179 TYR n 
1 180 ASN n 
1 181 ALA n 
1 182 ILE n 
1 183 MET n 
1 184 THR n 
1 185 LEU n 
1 186 SER n 
1 187 ASN n 
1 188 LEU n 
1 189 ILE n 
1 190 LYS n 
1 191 TYR n 
1 192 ALA n 
1 193 SER n 
1 194 CYS n 
1 195 SER n 
1 196 ILE n 
1 197 VAL n 
1 198 LEU n 
1 199 ASP n 
1 200 ASN n 
1 201 GLU n 
1 202 ALA n 
1 203 LEU n 
1 204 PHE n 
1 205 SER n 
1 206 ILE n 
1 207 ALA n 
1 208 GLU n 
1 209 LYS n 
1 210 LYS n 
1 211 LEU n 
1 212 GLU n 
1 213 VAL n 
1 214 GLU n 
1 215 ASN n 
1 216 PRO n 
1 217 SER n 
1 218 LEU n 
1 219 GLU n 
1 220 ASP n 
1 221 LEU n 
1 222 ASN n 
1 223 LEU n 
1 224 ILE n 
1 225 ILE n 
1 226 ALA n 
1 227 GLN n 
1 228 VAL n 
1 229 LEU n 
1 230 THR n 
1 231 ASN n 
1 232 VAL n 
1 233 THR n 
1 234 ALA n 
1 235 SER n 
1 236 LEU n 
1 237 ARG n 
1 238 PHE n 
1 239 SER n 
1 240 GLY n 
1 241 THR n 
1 242 LEU n 
1 243 ASN n 
1 244 LEU n 
1 245 ASP n 
1 246 LEU n 
1 247 GLY n 
1 248 LYS n 
1 249 LEU n 
1 250 VAL n 
1 251 THR n 
1 252 ASN n 
1 253 LEU n 
1 254 VAL n 
1 255 PRO n 
1 256 PHE n 
1 257 SER n 
1 258 ASN n 
1 259 LEU n 
1 260 HIS n 
1 261 PHE n 
1 262 LEU n 
1 263 MET n 
1 264 ALA n 
1 265 SER n 
1 266 THR n 
1 267 ALA n 
1 268 PRO n 
1 269 LEU n 
1 270 VAL n 
1 271 LEU n 
1 272 ALA n 
1 273 GLY n 
1 274 LYS n 
1 275 GLU n 
1 276 SER n 
1 277 TYR n 
1 278 GLU n 
1 279 LYS n 
1 280 MET n 
1 281 THR n 
1 282 ALA n 
1 283 LYS n 
1 284 GLU n 
1 285 LEU n 
1 286 SER n 
1 287 ALA n 
1 288 GLN n 
1 289 VAL n 
1 290 PHE n 
1 291 GLY n 
1 292 ASP n 
1 293 GLU n 
1 294 TYR n 
1 295 ILE n 
1 296 CYS n 
1 297 ALA n 
1 298 ALA n 
1 299 CYS n 
1 300 LYS n 
1 301 PRO n 
1 302 THR n 
1 303 THR n 
1 304 GLY n 
1 305 ARG n 
1 306 TYR n 
1 307 LEU n 
1 308 ALA n 
1 309 ALA n 
1 310 SER n 
1 311 VAL n 
1 312 LEU n 
1 313 PHE n 
1 314 ARG n 
1 315 GLY n 
1 316 ALA n 
1 317 VAL n 
1 318 LYS n 
1 319 THR n 
1 320 SER n 
1 321 ASP n 
1 322 VAL n 
1 323 ASN n 
1 324 GLU n 
1 325 ALA n 
1 326 MET n 
1 327 ALA n 
1 328 THR n 
1 329 VAL n 
1 330 LYS n 
1 331 GLU n 
1 332 GLN n 
1 333 ASN n 
1 334 SER n 
1 335 PHE n 
1 336 VAL n 
1 337 ASN n 
1 338 TRP n 
1 339 ILE n 
1 340 PRO n 
1 341 THR n 
1 342 GLY n 
1 343 PHE n 
1 344 LYS n 
1 345 ILE n 
1 346 SER n 
1 347 LYS n 
1 348 SER n 
1 349 GLU n 
1 350 THR n 
1 351 SER n 
1 352 PRO n 
1 353 LYS n 
1 354 ASP n 
1 355 SER n 
1 356 ALA n 
1 357 LEU n 
1 358 GLY n 
1 359 VAL n 
1 360 ILE n 
1 361 MET n 
1 362 LEU n 
1 363 GLY n 
1 364 ASN n 
1 365 ASN n 
1 366 SER n 
1 367 GLU n 
1 368 ILE n 
1 369 VAL n 
1 370 SER n 
1 371 VAL n 
1 372 PHE n 
1 373 GLU n 
1 374 ARG n 
1 375 ILE n 
1 376 GLY n 
1 377 ALA n 
1 378 ASN n 
1 379 PHE n 
1 380 ASP n 
1 381 ARG n 
1 382 LEU n 
1 383 TRP n 
1 384 SER n 
1 385 ARG n 
1 386 LYS n 
1 387 ALA n 
1 388 PHE n 
1 389 ALA n 
1 390 HIS n 
1 391 TRP n 
1 392 PHE n 
1 393 THR n 
1 394 ASP n 
1 395 SER n 
1 396 GLY n 
1 397 PHE n 
1 398 GLU n 
1 399 GLU n 
1 400 LYS n 
1 401 ASP n 
1 402 LEU n 
1 403 ASP n 
1 404 ASP n 
1 405 ALA n 
1 406 ARG n 
1 407 ALA n 
1 408 LEU n 
1 409 VAL n 
1 410 GLN n 
1 411 LYS n 
1 412 VAL n 
1 413 ILE n 
1 414 ASP n 
1 415 ASP n 
1 416 TYR n 
1 417 ARG n 
1 418 LYS n 
1 419 LEU n 
1 420 THR n 
1 421 GLU n 
1 422 ASP n 
1 423 ALA n 
2 1   MET n 
2 2   ALA n 
2 3   ARG n 
2 4   GLU n 
2 5   VAL n 
2 6   ILE n 
2 7   THR n 
2 8   ILE n 
2 9   HIS n 
2 10  VAL n 
2 11  GLY n 
2 12  GLU n 
2 13  LEU n 
2 14  GLY n 
2 15  ILE n 
2 16  GLN n 
2 17  ILE n 
2 18  ALA n 
2 19  PRO n 
2 20  ASN n 
2 21  PHE n 
2 22  TRP n 
2 23  LYS n 
2 24  TYR n 
2 25  LEU n 
2 26  CYS n 
2 27  ASP n 
2 28  GLU n 
2 29  HIS n 
2 30  ASN n 
2 31  ILE n 
2 32  ASP n 
2 33  TYR n 
2 34  LYS n 
2 35  GLY n 
2 36  GLN n 
2 37  GLU n 
2 38  LYS n 
2 39  GLY n 
2 40  LYS n 
2 41  ILE n 
2 42  ARG n 
2 43  GLY n 
2 44  VAL n 
2 45  ILE n 
2 46  ASP n 
2 47  ASN n 
2 48  PHE n 
2 49  PHE n 
2 50  GLU n 
2 51  LYS n 
2 52  ALA n 
2 53  SER n 
2 54  ILE n 
2 55  GLY n 
2 56  LYS n 
2 57  TRP n 
2 58  ILE n 
2 59  PRO n 
2 60  ARG n 
2 61  THR n 
2 62  ILE n 
2 63  LEU n 
2 64  VAL n 
2 65  ASP n 
2 66  LEU n 
2 67  GLY n 
2 68  PRO n 
2 69  ASN n 
2 70  ALA n 
2 71  ILE n 
2 72  ARG n 
2 73  LYS n 
2 74  VAL n 
2 75  THR n 
2 76  LYS n 
2 77  LYS n 
2 78  ASP n 
2 79  MET n 
2 80  LYS n 
2 81  ASP n 
2 82  PHE n 
2 83  PHE n 
2 84  ASP n 
2 85  PRO n 
2 86  LYS n 
2 87  ARG n 
2 88  CYS n 
2 89  VAL n 
2 90  MET n 
2 91  GLY n 
2 92  LEU n 
2 93  ALA n 
2 94  GLY n 
2 95  ASP n 
2 96  ALA n 
2 97  ASN n 
2 98  LEU n 
2 99  PHE n 
2 100 ALA n 
2 101 LYS n 
2 102 GLY n 
2 103 TYR n 
2 104 TYR n 
2 105 SER n 
2 106 TYR n 
2 107 GLY n 
2 108 THR n 
2 109 ARG n 
2 110 PHE n 
2 111 MET n 
2 112 GLU n 
2 113 GLU n 
2 114 ILE n 
2 115 MET n 
2 116 ASP n 
2 117 LYS n 
2 118 ILE n 
2 119 GLN n 
2 120 LYS n 
2 121 GLU n 
2 122 VAL n 
2 123 ASP n 
2 124 GLN n 
2 125 THR n 
2 126 GLU n 
2 127 HIS n 
2 128 LEU n 
2 129 GLN n 
2 130 GLY n 
2 131 PHE n 
2 132 ILE n 
2 133 VAL n 
2 134 VAL n 
2 135 HIS n 
2 136 SER n 
2 137 ILE n 
2 138 GLY n 
2 139 ASP n 
2 140 GLY n 
2 141 THR n 
2 142 GLY n 
2 143 ALA n 
2 144 GLY n 
2 145 LEU n 
2 146 ALA n 
2 147 PRO n 
2 148 LEU n 
2 149 ILE n 
2 150 MET n 
2 151 GLU n 
2 152 ALA n 
2 153 ILE n 
2 154 LYS n 
2 155 LYS n 
2 156 LYS n 
2 157 HIS n 
2 158 PRO n 
2 159 LYS n 
2 160 LEU n 
2 161 VAL n 
2 162 MET n 
2 163 MET n 
2 164 SER n 
2 165 TYR n 
2 166 SER n 
2 167 ILE n 
2 168 VAL n 
2 169 PRO n 
2 170 SER n 
2 171 GLN n 
2 172 ASN n 
2 173 MET n 
2 174 ASP n 
2 175 CYS n 
2 176 SER n 
2 177 THR n 
2 178 ILE n 
2 179 LEU n 
2 180 PRO n 
2 181 TYR n 
2 182 ASN n 
2 183 ALA n 
2 184 ILE n 
2 185 LEU n 
2 186 SER n 
2 187 LEU n 
2 188 ASP n 
2 189 LYS n 
2 190 LEU n 
2 191 THR n 
2 192 SER n 
2 193 CYS n 
2 194 ALA n 
2 195 ASP n 
2 196 ILE n 
2 197 SER n 
2 198 MET n 
2 199 ILE n 
2 200 ILE n 
2 201 ASP n 
2 202 ASN n 
2 203 ASP n 
2 204 SER n 
2 205 ILE n 
2 206 TYR n 
2 207 ARG n 
2 208 ILE n 
2 209 VAL n 
2 210 ALA n 
2 211 THR n 
2 212 GLN n 
2 213 GLY n 
2 214 LYS n 
2 215 GLU n 
2 216 ASN n 
2 217 GLU n 
2 218 LEU n 
2 219 SER n 
2 220 GLU n 
2 221 SER n 
2 222 ILE n 
2 223 PHE n 
2 224 ASP n 
2 225 GLN n 
2 226 VAL n 
2 227 LEU n 
2 228 ALA n 
2 229 LYS n 
2 230 ALA n 
2 231 LEU n 
2 232 VAL n 
2 233 GLU n 
2 234 ILE n 
2 235 THR n 
2 236 ALA n 
2 237 THR n 
2 238 LEU n 
2 239 ARG n 
2 240 PHE n 
2 241 ASN n 
2 242 SER n 
2 243 PRO n 
2 244 LEU n 
2 245 ASN n 
2 246 ARG n 
2 247 SER n 
2 248 MET n 
2 249 MET n 
2 250 GLU n 
2 251 MET n 
2 252 SER n 
2 253 THR n 
2 254 ASN n 
2 255 LEU n 
2 256 VAL n 
2 257 PRO n 
2 258 PHE n 
2 259 PRO n 
2 260 ARG n 
2 261 ASN n 
2 262 HIS n 
2 263 PHE n 
2 264 LEU n 
2 265 MET n 
2 266 THR n 
2 267 SER n 
2 268 MET n 
2 269 SER n 
2 270 PRO n 
2 271 LEU n 
2 272 GLU n 
2 273 THR n 
2 274 SER n 
2 275 LEU n 
2 276 THR n 
2 277 SER n 
2 278 ALA n 
2 279 HIS n 
2 280 GLN n 
2 281 LYS n 
2 282 ILE n 
2 283 GLU n 
2 284 THR n 
2 285 LYS n 
2 286 GLU n 
2 287 LEU n 
2 288 MET n 
2 289 GLN n 
2 290 ASP n 
2 291 LEU n 
2 292 ILE n 
2 293 ASP n 
2 294 GLN n 
2 295 ASP n 
2 296 HIS n 
2 297 ILE n 
2 298 LEU n 
2 299 ALA n 
2 300 PRO n 
2 301 ILE n 
2 302 THR n 
2 303 VAL n 
2 304 GLU n 
2 305 LYS n 
2 306 GLY n 
2 307 VAL n 
2 308 PHE n 
2 309 THR n 
2 310 ALA n 
2 311 PHE n 
2 312 VAL n 
2 313 ILE n 
2 314 ALA n 
2 315 LEU n 
2 316 ARG n 
2 317 GLY n 
2 318 GLU n 
2 319 ASN n 
2 320 PRO n 
2 321 HIS n 
2 322 SER n 
2 323 ILE n 
2 324 LEU n 
2 325 GLN n 
2 326 ASN n 
2 327 SER n 
2 328 ILE n 
2 329 LYS n 
2 330 GLY n 
2 331 PHE n 
2 332 GLY n 
2 333 ASP n 
2 334 ARG n 
2 335 VAL n 
2 336 LYS n 
2 337 PHE n 
2 338 SER n 
2 339 GLU n 
2 340 ILE n 
2 341 PHE n 
2 342 PRO n 
2 343 THR n 
2 344 ALA n 
2 345 ILE n 
2 346 LYS n 
2 347 ALA n 
2 348 ASP n 
2 349 SER n 
2 350 THR n 
2 351 THR n 
2 352 LEU n 
2 353 THR n 
2 354 ASP n 
2 355 GLU n 
2 356 LYS n 
2 357 LEU n 
2 358 ALA n 
2 359 ARG n 
2 360 SER n 
2 361 GLY n 
2 362 ILE n 
2 363 THR n 
2 364 LEU n 
2 365 MET n 
2 366 ASN n 
2 367 HIS n 
2 368 SER n 
2 369 GLY n 
2 370 VAL n 
2 371 ALA n 
2 372 ASN n 
2 373 LEU n 
2 374 PHE n 
2 375 GLN n 
2 376 PHE n 
2 377 LEU n 
2 378 LEU n 
2 379 THR n 
2 380 GLN n 
2 381 PHE n 
2 382 GLU n 
2 383 LEU n 
2 384 MET n 
2 385 TYR n 
2 386 ASP n 
2 387 HIS n 
2 388 ASP n 
2 389 ALA n 
2 390 PHE n 
2 391 THR n 
2 392 THR n 
2 393 TRP n 
2 394 TYR n 
2 395 TYR n 
2 396 GLN n 
2 397 GLU n 
2 398 GLY n 
2 399 MET n 
2 400 GLN n 
2 401 PRO n 
2 402 SER n 
2 403 GLU n 
2 404 PHE n 
2 405 GLU n 
2 406 ALA n 
2 407 ALA n 
2 408 LYS n 
2 409 ASN n 
2 410 ASN n 
2 411 ILE n 
2 412 GLN n 
2 413 LYS n 
2 414 LEU n 
2 415 ILE n 
2 416 THR n 
2 417 GLU n 
2 418 TYR n 
2 419 LYS n 
2 420 GLN n 
2 421 ASP n 
2 422 GLU n 
2 423 TYR n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 423 ? ? ? ? ? ? ? ? ? 'Candidatus Lokiarchaeum ossiferum' 2951803 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 423 ? ? ? ? ? ? ? ? ? 'Candidatus Lokiarchaeum ossiferum' 2951803 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                     ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                    ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                  ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'             ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                    ? 'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                   ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'             ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                     ? 'C2 H5 N O2'        75.067  
GTP non-polymer         n "GUANOSINE-5'-TRIPHOSPHATE" ? 'C10 H16 N5 O14 P3' 523.180 
HIS 'L-peptide linking' y HISTIDINE                   ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                  ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                     ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                      ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                  ? 'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE               ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                     ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                      ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                   ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                  ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                    ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                      ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   2   ALA ALA A . n 
A 1 3   GLY 3   3   3   GLY GLY A . n 
A 1 4   GLU 4   4   4   GLU GLU A . n 
A 1 5   ILE 5   5   5   ILE ILE A . n 
A 1 6   VAL 6   6   6   VAL VAL A . n 
A 1 7   CYS 7   7   7   CYS CYS A . n 
A 1 8   ILE 8   8   8   ILE ILE A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  VAL 10  10  10  VAL VAL A . n 
A 1 11  GLY 11  11  11  GLY GLY A . n 
A 1 12  GLN 12  12  12  GLN GLN A . n 
A 1 13  ALA 13  13  13  ALA ALA A . n 
A 1 14  GLY 14  14  14  GLY GLY A . n 
A 1 15  ASN 15  15  15  ASN ASN A . n 
A 1 16  GLN 16  16  16  GLN GLN A . n 
A 1 17  ILE 17  17  17  ILE ILE A . n 
A 1 18  ALA 18  18  18  ALA ALA A . n 
A 1 19  GLY 19  19  19  GLY GLY A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  PHE 21  21  21  PHE PHE A . n 
A 1 22  TRP 22  22  22  TRP TRP A . n 
A 1 23  GLN 23  23  23  GLN GLN A . n 
A 1 24  LYS 24  24  24  LYS LYS A . n 
A 1 25  ILE 25  25  25  ILE ILE A . n 
A 1 26  CYS 26  26  26  CYS CYS A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  GLU 28  28  28  GLU GLU A . n 
A 1 29  HIS 29  29  29  HIS HIS A . n 
A 1 30  GLY 30  30  30  GLY GLY A . n 
A 1 31  ILE 31  31  31  ILE ILE A . n 
A 1 32  ASP 32  32  32  ASP ASP A . n 
A 1 33  PRO 33  33  33  PRO PRO A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  ASN 35  35  35  ASN ASN A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  LYS 37  37  37  LYS LYS A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  ILE 39  39  39  ILE ILE A . n 
A 1 40  ASP 40  40  40  ASP ASP A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  GLY 43  43  43  GLY GLY A . n 
A 1 44  ASP 44  44  44  ASP ASP A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  ASP 46  46  46  ASP ASP A . n 
A 1 47  ILE 47  47  47  ILE ILE A . n 
A 1 48  PHE 48  48  48  PHE PHE A . n 
A 1 49  PHE 49  49  49  PHE PHE A . n 
A 1 50  ASN 50  50  50  ASN ASN A . n 
A 1 51  THR 51  51  51  THR THR A . n 
A 1 52  ILE 52  52  52  ILE ILE A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  ASP 54  54  54  ASP ASP A . n 
A 1 55  LYS 55  55  55  LYS LYS A . n 
A 1 56  TYR 56  56  56  TYR TYR A . n 
A 1 57  ILE 57  57  57  ILE ILE A . n 
A 1 58  PRO 58  58  58  PRO PRO A . n 
A 1 59  ARG 59  59  59  ARG ARG A . n 
A 1 60  ALA 60  60  60  ALA ALA A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  VAL 62  62  62  VAL VAL A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  ASP 64  64  64  ASP ASP A . n 
A 1 65  LEU 65  65  65  LEU LEU A . n 
A 1 66  GLU 66  66  66  GLU GLU A . n 
A 1 67  PRO 67  67  67  PRO PRO A . n 
A 1 68  ALA 68  68  68  ALA ALA A . n 
A 1 69  VAL 69  69  69  VAL VAL A . n 
A 1 70  VAL 70  70  70  VAL VAL A . n 
A 1 71  GLU 71  71  71  GLU GLU A . n 
A 1 72  ASN 72  72  72  ASN ASN A . n 
A 1 73  ILE 73  73  73  ILE ILE A . n 
A 1 74  ARG 74  74  74  ARG ARG A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  LYS 76  76  76  LYS LYS A . n 
A 1 77  PHE 77  77  77  PHE PHE A . n 
A 1 78  GLY 78  78  78  GLY GLY A . n 
A 1 79  THR 79  79  79  THR THR A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  PHE 81  81  81  PHE PHE A . n 
A 1 82  ASP 82  82  82  ASP ASP A . n 
A 1 83  PRO 83  83  83  PRO PRO A . n 
A 1 84  LYS 84  84  84  LYS LYS A . n 
A 1 85  SER 85  85  85  SER SER A . n 
A 1 86  ILE 86  86  86  ILE ILE A . n 
A 1 87  VAL 87  87  87  VAL VAL A . n 
A 1 88  SER 88  88  88  SER SER A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  ASP 91  91  91  ASP ASP A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  ASN 95  95  95  ASN ASN A . n 
A 1 96  ASN 96  96  96  ASN ASN A . n 
A 1 97  PHE 97  97  97  PHE PHE A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  ILE 99  99  99  ILE ILE A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 PHE 101 101 101 PHE PHE A . n 
A 1 102 ASN 102 102 102 ASN ASN A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 HIS 104 104 104 HIS HIS A . n 
A 1 105 GLY 105 105 105 GLY GLY A . n 
A 1 106 ALA 106 106 106 ALA ALA A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 THR 108 108 108 THR THR A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 GLU 110 110 110 GLU GLU A . n 
A 1 111 LYS 111 111 111 LYS LYS A . n 
A 1 112 VAL 112 112 112 VAL VAL A . n 
A 1 113 MET 113 113 113 MET MET A . n 
A 1 114 GLN 114 114 114 GLN GLN A . n 
A 1 115 VAL 115 115 115 VAL VAL A . n 
A 1 116 VAL 116 116 116 VAL VAL A . n 
A 1 117 GLU 117 117 117 GLU GLU A . n 
A 1 118 GLN 118 118 118 GLN GLN A . n 
A 1 119 ARG 119 119 119 ARG ARG A . n 
A 1 120 VAL 120 120 120 VAL VAL A . n 
A 1 121 SER 121 121 121 SER SER A . n 
A 1 122 GLU 122 122 122 GLU GLU A . n 
A 1 123 THR 123 123 123 THR THR A . n 
A 1 124 GLU 124 124 124 GLU GLU A . n 
A 1 125 SER 125 125 125 SER SER A . n 
A 1 126 ILE 126 126 126 ILE ILE A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 PHE 129 129 129 PHE PHE A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 LEU 131 131 131 LEU LEU A . n 
A 1 132 THR 132 132 132 THR THR A . n 
A 1 133 HIS 133 133 133 HIS HIS A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 CYS 135 135 135 CYS CYS A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 THR 139 139 139 THR THR A . n 
A 1 140 GLY 140 140 140 GLY GLY A . n 
A 1 141 SER 141 141 141 SER SER A . n 
A 1 142 GLY 142 142 142 GLY GLY A . n 
A 1 143 PHE 143 143 143 PHE PHE A . n 
A 1 144 GLY 144 144 144 GLY GLY A . n 
A 1 145 SER 145 145 145 SER SER A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 ILE 147 147 147 ILE ILE A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 LYS 149 149 149 LYS LYS A . n 
A 1 150 THR 150 150 150 THR THR A . n 
A 1 151 ILE 151 151 151 ILE ILE A . n 
A 1 152 ARG 152 152 152 ARG ARG A . n 
A 1 153 GLU 153 153 153 GLU GLU A . n 
A 1 154 ARG 154 154 154 ARG ARG A . n 
A 1 155 TYR 155 155 155 TYR TYR A . n 
A 1 156 PRO 156 156 156 PRO PRO A . n 
A 1 157 LYS 157 157 157 LYS LYS A . n 
A 1 158 VAL 158 158 158 VAL VAL A . n 
A 1 159 PRO 159 159 159 PRO PRO A . n 
A 1 160 ILE 160 160 160 ILE ILE A . n 
A 1 161 PHE 161 161 161 PHE PHE A . n 
A 1 162 THR 162 162 162 THR THR A . n 
A 1 163 PHE 163 163 163 PHE PHE A . n 
A 1 164 SER 164 164 164 SER SER A . n 
A 1 165 ILE 165 165 165 ILE ILE A . n 
A 1 166 PHE 166 166 166 PHE PHE A . n 
A 1 167 PRO 167 167 167 PRO PRO A . n 
A 1 168 SER 168 168 168 SER SER A . n 
A 1 169 PRO 169 169 169 PRO PRO A . n 
A 1 170 LYS 170 170 170 LYS LYS A . n 
A 1 171 ILE 171 171 171 ILE ILE A . n 
A 1 172 SER 172 172 172 SER SER A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 THR 174 174 174 THR THR A . n 
A 1 175 VAL 175 175 175 VAL VAL A . n 
A 1 176 VAL 176 176 176 VAL VAL A . n 
A 1 177 GLU 177 177 177 GLU GLU A . n 
A 1 178 PRO 178 178 178 PRO PRO A . n 
A 1 179 TYR 179 179 179 TYR TYR A . n 
A 1 180 ASN 180 180 180 ASN ASN A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 ILE 182 182 182 ILE ILE A . n 
A 1 183 MET 183 183 183 MET MET A . n 
A 1 184 THR 184 184 184 THR THR A . n 
A 1 185 LEU 185 185 185 LEU LEU A . n 
A 1 186 SER 186 186 186 SER SER A . n 
A 1 187 ASN 187 187 187 ASN ASN A . n 
A 1 188 LEU 188 188 188 LEU LEU A . n 
A 1 189 ILE 189 189 189 ILE ILE A . n 
A 1 190 LYS 190 190 190 LYS LYS A . n 
A 1 191 TYR 191 191 191 TYR TYR A . n 
A 1 192 ALA 192 192 192 ALA ALA A . n 
A 1 193 SER 193 193 193 SER SER A . n 
A 1 194 CYS 194 194 194 CYS CYS A . n 
A 1 195 SER 195 195 195 SER SER A . n 
A 1 196 ILE 196 196 196 ILE ILE A . n 
A 1 197 VAL 197 197 197 VAL VAL A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 ASP 199 199 199 ASP ASP A . n 
A 1 200 ASN 200 200 200 ASN ASN A . n 
A 1 201 GLU 201 201 201 GLU GLU A . n 
A 1 202 ALA 202 202 202 ALA ALA A . n 
A 1 203 LEU 203 203 203 LEU LEU A . n 
A 1 204 PHE 204 204 204 PHE PHE A . n 
A 1 205 SER 205 205 205 SER SER A . n 
A 1 206 ILE 206 206 206 ILE ILE A . n 
A 1 207 ALA 207 207 207 ALA ALA A . n 
A 1 208 GLU 208 208 208 GLU GLU A . n 
A 1 209 LYS 209 209 209 LYS LYS A . n 
A 1 210 LYS 210 210 210 LYS LYS A . n 
A 1 211 LEU 211 211 211 LEU LEU A . n 
A 1 212 GLU 212 212 212 GLU GLU A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 GLU 214 214 214 GLU GLU A . n 
A 1 215 ASN 215 215 215 ASN ASN A . n 
A 1 216 PRO 216 216 216 PRO PRO A . n 
A 1 217 SER 217 217 217 SER SER A . n 
A 1 218 LEU 218 218 218 LEU LEU A . n 
A 1 219 GLU 219 219 219 GLU GLU A . n 
A 1 220 ASP 220 220 220 ASP ASP A . n 
A 1 221 LEU 221 221 221 LEU LEU A . n 
A 1 222 ASN 222 222 222 ASN ASN A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 ILE 224 224 224 ILE ILE A . n 
A 1 225 ILE 225 225 225 ILE ILE A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 GLN 227 227 227 GLN GLN A . n 
A 1 228 VAL 228 228 228 VAL VAL A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 THR 230 230 230 THR THR A . n 
A 1 231 ASN 231 231 231 ASN ASN A . n 
A 1 232 VAL 232 232 232 VAL VAL A . n 
A 1 233 THR 233 233 233 THR THR A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 SER 235 235 235 SER SER A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 ARG 237 237 237 ARG ARG A . n 
A 1 238 PHE 238 238 238 PHE PHE A . n 
A 1 239 SER 239 239 239 SER SER A . n 
A 1 240 GLY 240 240 240 GLY GLY A . n 
A 1 241 THR 241 241 241 THR THR A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 ASN 243 243 243 ASN ASN A . n 
A 1 244 LEU 244 244 244 LEU LEU A . n 
A 1 245 ASP 245 245 245 ASP ASP A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 GLY 247 247 247 GLY GLY A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 VAL 250 250 250 VAL VAL A . n 
A 1 251 THR 251 251 251 THR THR A . n 
A 1 252 ASN 252 252 252 ASN ASN A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 PRO 255 255 255 PRO PRO A . n 
A 1 256 PHE 256 256 256 PHE PHE A . n 
A 1 257 SER 257 257 257 SER SER A . n 
A 1 258 ASN 258 258 258 ASN ASN A . n 
A 1 259 LEU 259 259 259 LEU LEU A . n 
A 1 260 HIS 260 260 260 HIS HIS A . n 
A 1 261 PHE 261 261 261 PHE PHE A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 MET 263 263 263 MET MET A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 SER 265 265 265 SER SER A . n 
A 1 266 THR 266 266 266 THR THR A . n 
A 1 267 ALA 267 267 267 ALA ALA A . n 
A 1 268 PRO 268 268 268 PRO PRO A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 VAL 270 270 270 VAL VAL A . n 
A 1 271 LEU 271 271 271 LEU LEU A . n 
A 1 272 ALA 272 272 272 ALA ALA A . n 
A 1 273 GLY 273 273 273 GLY GLY A . n 
A 1 274 LYS 274 274 274 LYS LYS A . n 
A 1 275 GLU 275 275 275 GLU GLU A . n 
A 1 276 SER 276 276 276 SER SER A . n 
A 1 277 TYR 277 277 277 TYR TYR A . n 
A 1 278 GLU 278 278 278 GLU GLU A . n 
A 1 279 LYS 279 279 279 LYS LYS A . n 
A 1 280 MET 280 280 280 MET MET A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 LYS 283 283 283 LYS LYS A . n 
A 1 284 GLU 284 284 284 GLU GLU A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 SER 286 286 286 SER SER A . n 
A 1 287 ALA 287 287 287 ALA ALA A . n 
A 1 288 GLN 288 288 288 GLN GLN A . n 
A 1 289 VAL 289 289 289 VAL VAL A . n 
A 1 290 PHE 290 290 290 PHE PHE A . n 
A 1 291 GLY 291 291 291 GLY GLY A . n 
A 1 292 ASP 292 292 292 ASP ASP A . n 
A 1 293 GLU 293 293 293 GLU GLU A . n 
A 1 294 TYR 294 294 294 TYR TYR A . n 
A 1 295 ILE 295 295 295 ILE ILE A . n 
A 1 296 CYS 296 296 296 CYS CYS A . n 
A 1 297 ALA 297 297 297 ALA ALA A . n 
A 1 298 ALA 298 298 298 ALA ALA A . n 
A 1 299 CYS 299 299 299 CYS CYS A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 PRO 301 301 301 PRO PRO A . n 
A 1 302 THR 302 302 302 THR THR A . n 
A 1 303 THR 303 303 303 THR THR A . n 
A 1 304 GLY 304 304 304 GLY GLY A . n 
A 1 305 ARG 305 305 305 ARG ARG A . n 
A 1 306 TYR 306 306 306 TYR TYR A . n 
A 1 307 LEU 307 307 307 LEU LEU A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 SER 310 310 310 SER SER A . n 
A 1 311 VAL 311 311 311 VAL VAL A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 PHE 313 313 313 PHE PHE A . n 
A 1 314 ARG 314 314 314 ARG ARG A . n 
A 1 315 GLY 315 315 315 GLY GLY A . n 
A 1 316 ALA 316 316 316 ALA ALA A . n 
A 1 317 VAL 317 317 317 VAL VAL A . n 
A 1 318 LYS 318 318 318 LYS LYS A . n 
A 1 319 THR 319 319 319 THR THR A . n 
A 1 320 SER 320 320 320 SER SER A . n 
A 1 321 ASP 321 321 321 ASP ASP A . n 
A 1 322 VAL 322 322 322 VAL VAL A . n 
A 1 323 ASN 323 323 323 ASN ASN A . n 
A 1 324 GLU 324 324 324 GLU GLU A . n 
A 1 325 ALA 325 325 325 ALA ALA A . n 
A 1 326 MET 326 326 326 MET MET A . n 
A 1 327 ALA 327 327 327 ALA ALA A . n 
A 1 328 THR 328 328 328 THR THR A . n 
A 1 329 VAL 329 329 329 VAL VAL A . n 
A 1 330 LYS 330 330 330 LYS LYS A . n 
A 1 331 GLU 331 331 331 GLU GLU A . n 
A 1 332 GLN 332 332 332 GLN GLN A . n 
A 1 333 ASN 333 333 333 ASN ASN A . n 
A 1 334 SER 334 334 334 SER SER A . n 
A 1 335 PHE 335 335 335 PHE PHE A . n 
A 1 336 VAL 336 336 336 VAL VAL A . n 
A 1 337 ASN 337 337 337 ASN ASN A . n 
A 1 338 TRP 338 338 338 TRP TRP A . n 
A 1 339 ILE 339 339 339 ILE ILE A . n 
A 1 340 PRO 340 340 340 PRO PRO A . n 
A 1 341 THR 341 341 341 THR THR A . n 
A 1 342 GLY 342 342 342 GLY GLY A . n 
A 1 343 PHE 343 343 343 PHE PHE A . n 
A 1 344 LYS 344 344 344 LYS LYS A . n 
A 1 345 ILE 345 345 345 ILE ILE A . n 
A 1 346 SER 346 346 346 SER SER A . n 
A 1 347 LYS 347 347 347 LYS LYS A . n 
A 1 348 SER 348 348 348 SER SER A . n 
A 1 349 GLU 349 349 349 GLU GLU A . n 
A 1 350 THR 350 350 350 THR THR A . n 
A 1 351 SER 351 351 351 SER SER A . n 
A 1 352 PRO 352 352 352 PRO PRO A . n 
A 1 353 LYS 353 353 353 LYS LYS A . n 
A 1 354 ASP 354 354 354 ASP ASP A . n 
A 1 355 SER 355 355 355 SER SER A . n 
A 1 356 ALA 356 356 356 ALA ALA A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 GLY 358 358 358 GLY GLY A . n 
A 1 359 VAL 359 359 359 VAL VAL A . n 
A 1 360 ILE 360 360 360 ILE ILE A . n 
A 1 361 MET 361 361 361 MET MET A . n 
A 1 362 LEU 362 362 362 LEU LEU A . n 
A 1 363 GLY 363 363 363 GLY GLY A . n 
A 1 364 ASN 364 364 364 ASN ASN A . n 
A 1 365 ASN 365 365 365 ASN ASN A . n 
A 1 366 SER 366 366 366 SER SER A . n 
A 1 367 GLU 367 367 367 GLU GLU A . n 
A 1 368 ILE 368 368 368 ILE ILE A . n 
A 1 369 VAL 369 369 369 VAL VAL A . n 
A 1 370 SER 370 370 370 SER SER A . n 
A 1 371 VAL 371 371 371 VAL VAL A . n 
A 1 372 PHE 372 372 372 PHE PHE A . n 
A 1 373 GLU 373 373 373 GLU GLU A . n 
A 1 374 ARG 374 374 374 ARG ARG A . n 
A 1 375 ILE 375 375 375 ILE ILE A . n 
A 1 376 GLY 376 376 376 GLY GLY A . n 
A 1 377 ALA 377 377 377 ALA ALA A . n 
A 1 378 ASN 378 378 378 ASN ASN A . n 
A 1 379 PHE 379 379 379 PHE PHE A . n 
A 1 380 ASP 380 380 380 ASP ASP A . n 
A 1 381 ARG 381 381 381 ARG ARG A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 TRP 383 383 383 TRP TRP A . n 
A 1 384 SER 384 384 384 SER SER A . n 
A 1 385 ARG 385 385 385 ARG ARG A . n 
A 1 386 LYS 386 386 386 LYS LYS A . n 
A 1 387 ALA 387 387 387 ALA ALA A . n 
A 1 388 PHE 388 388 388 PHE PHE A . n 
A 1 389 ALA 389 389 389 ALA ALA A . n 
A 1 390 HIS 390 390 390 HIS HIS A . n 
A 1 391 TRP 391 391 391 TRP TRP A . n 
A 1 392 PHE 392 392 392 PHE PHE A . n 
A 1 393 THR 393 393 393 THR THR A . n 
A 1 394 ASP 394 394 394 ASP ASP A . n 
A 1 395 SER 395 395 395 SER SER A . n 
A 1 396 GLY 396 396 396 GLY GLY A . n 
A 1 397 PHE 397 397 397 PHE PHE A . n 
A 1 398 GLU 398 398 398 GLU GLU A . n 
A 1 399 GLU 399 399 399 GLU GLU A . n 
A 1 400 LYS 400 400 400 LYS LYS A . n 
A 1 401 ASP 401 401 401 ASP ASP A . n 
A 1 402 LEU 402 402 402 LEU LEU A . n 
A 1 403 ASP 403 403 403 ASP ASP A . n 
A 1 404 ASP 404 404 404 ASP ASP A . n 
A 1 405 ALA 405 405 405 ALA ALA A . n 
A 1 406 ARG 406 406 406 ARG ARG A . n 
A 1 407 ALA 407 407 407 ALA ALA A . n 
A 1 408 LEU 408 408 408 LEU LEU A . n 
A 1 409 VAL 409 409 409 VAL VAL A . n 
A 1 410 GLN 410 410 410 GLN GLN A . n 
A 1 411 LYS 411 411 411 LYS LYS A . n 
A 1 412 VAL 412 412 412 VAL VAL A . n 
A 1 413 ILE 413 413 413 ILE ILE A . n 
A 1 414 ASP 414 414 414 ASP ASP A . n 
A 1 415 ASP 415 415 415 ASP ASP A . n 
A 1 416 TYR 416 416 416 TYR TYR A . n 
A 1 417 ARG 417 417 417 ARG ARG A . n 
A 1 418 LYS 418 418 418 LYS LYS A . n 
A 1 419 LEU 419 419 419 LEU LEU A . n 
A 1 420 THR 420 420 420 THR THR A . n 
A 1 421 GLU 421 421 421 GLU GLU A . n 
A 1 422 ASP 422 422 422 ASP ASP A . n 
A 1 423 ALA 423 423 423 ALA ALA A . n 
B 2 1   MET 1   1   ?   ?   ?   D . n 
B 2 2   ALA 2   2   2   ALA ALA D . n 
B 2 3   ARG 3   3   3   ARG ARG D . n 
B 2 4   GLU 4   4   4   GLU GLU D . n 
B 2 5   VAL 5   5   5   VAL VAL D . n 
B 2 6   ILE 6   6   6   ILE ILE D . n 
B 2 7   THR 7   7   7   THR THR D . n 
B 2 8   ILE 8   8   8   ILE ILE D . n 
B 2 9   HIS 9   9   9   HIS HIS D . n 
B 2 10  VAL 10  10  10  VAL VAL D . n 
B 2 11  GLY 11  11  11  GLY GLY D . n 
B 2 12  GLU 12  12  12  GLU GLU D . n 
B 2 13  LEU 13  13  13  LEU LEU D . n 
B 2 14  GLY 14  14  14  GLY GLY D . n 
B 2 15  ILE 15  15  15  ILE ILE D . n 
B 2 16  GLN 16  16  16  GLN GLN D . n 
B 2 17  ILE 17  17  17  ILE ILE D . n 
B 2 18  ALA 18  18  18  ALA ALA D . n 
B 2 19  PRO 19  19  19  PRO PRO D . n 
B 2 20  ASN 20  20  20  ASN ASN D . n 
B 2 21  PHE 21  21  21  PHE PHE D . n 
B 2 22  TRP 22  22  22  TRP TRP D . n 
B 2 23  LYS 23  23  23  LYS LYS D . n 
B 2 24  TYR 24  24  24  TYR TYR D . n 
B 2 25  LEU 25  25  25  LEU LEU D . n 
B 2 26  CYS 26  26  26  CYS CYS D . n 
B 2 27  ASP 27  27  27  ASP ASP D . n 
B 2 28  GLU 28  28  28  GLU GLU D . n 
B 2 29  HIS 29  29  29  HIS HIS D . n 
B 2 30  ASN 30  30  30  ASN ASN D . n 
B 2 31  ILE 31  31  31  ILE ILE D . n 
B 2 32  ASP 32  32  32  ASP ASP D . n 
B 2 33  TYR 33  33  33  TYR TYR D . n 
B 2 34  LYS 34  34  34  LYS LYS D . n 
B 2 35  GLY 35  35  35  GLY GLY D . n 
B 2 36  GLN 36  36  36  GLN GLN D . n 
B 2 37  GLU 37  37  37  GLU GLU D . n 
B 2 38  LYS 38  38  38  LYS LYS D . n 
B 2 39  GLY 39  39  39  GLY GLY D . n 
B 2 40  LYS 40  40  40  LYS LYS D . n 
B 2 41  ILE 41  41  41  ILE ILE D . n 
B 2 42  ARG 42  42  42  ARG ARG D . n 
B 2 43  GLY 43  43  43  GLY GLY D . n 
B 2 44  VAL 44  44  44  VAL VAL D . n 
B 2 45  ILE 45  45  45  ILE ILE D . n 
B 2 46  ASP 46  46  46  ASP ASP D . n 
B 2 47  ASN 47  47  47  ASN ASN D . n 
B 2 48  PHE 48  48  48  PHE PHE D . n 
B 2 49  PHE 49  49  49  PHE PHE D . n 
B 2 50  GLU 50  50  50  GLU GLU D . n 
B 2 51  LYS 51  51  51  LYS LYS D . n 
B 2 52  ALA 52  52  52  ALA ALA D . n 
B 2 53  SER 53  53  53  SER SER D . n 
B 2 54  ILE 54  54  54  ILE ILE D . n 
B 2 55  GLY 55  55  55  GLY GLY D . n 
B 2 56  LYS 56  56  56  LYS LYS D . n 
B 2 57  TRP 57  57  57  TRP TRP D . n 
B 2 58  ILE 58  58  58  ILE ILE D . n 
B 2 59  PRO 59  59  59  PRO PRO D . n 
B 2 60  ARG 60  60  60  ARG ARG D . n 
B 2 61  THR 61  61  61  THR THR D . n 
B 2 62  ILE 62  62  62  ILE ILE D . n 
B 2 63  LEU 63  63  63  LEU LEU D . n 
B 2 64  VAL 64  64  64  VAL VAL D . n 
B 2 65  ASP 65  65  65  ASP ASP D . n 
B 2 66  LEU 66  66  66  LEU LEU D . n 
B 2 67  GLY 67  67  67  GLY GLY D . n 
B 2 68  PRO 68  68  68  PRO PRO D . n 
B 2 69  ASN 69  69  69  ASN ASN D . n 
B 2 70  ALA 70  70  70  ALA ALA D . n 
B 2 71  ILE 71  71  71  ILE ILE D . n 
B 2 72  ARG 72  72  72  ARG ARG D . n 
B 2 73  LYS 73  73  73  LYS LYS D . n 
B 2 74  VAL 74  74  74  VAL VAL D . n 
B 2 75  THR 75  75  75  THR THR D . n 
B 2 76  LYS 76  76  76  LYS LYS D . n 
B 2 77  LYS 77  77  77  LYS LYS D . n 
B 2 78  ASP 78  78  78  ASP ASP D . n 
B 2 79  MET 79  79  79  MET MET D . n 
B 2 80  LYS 80  80  80  LYS LYS D . n 
B 2 81  ASP 81  81  81  ASP ASP D . n 
B 2 82  PHE 82  82  82  PHE PHE D . n 
B 2 83  PHE 83  83  83  PHE PHE D . n 
B 2 84  ASP 84  84  84  ASP ASP D . n 
B 2 85  PRO 85  85  85  PRO PRO D . n 
B 2 86  LYS 86  86  86  LYS LYS D . n 
B 2 87  ARG 87  87  87  ARG ARG D . n 
B 2 88  CYS 88  88  88  CYS CYS D . n 
B 2 89  VAL 89  89  89  VAL VAL D . n 
B 2 90  MET 90  90  90  MET MET D . n 
B 2 91  GLY 91  91  91  GLY GLY D . n 
B 2 92  LEU 92  92  92  LEU LEU D . n 
B 2 93  ALA 93  93  93  ALA ALA D . n 
B 2 94  GLY 94  94  94  GLY GLY D . n 
B 2 95  ASP 95  95  95  ASP ASP D . n 
B 2 96  ALA 96  96  96  ALA ALA D . n 
B 2 97  ASN 97  97  97  ASN ASN D . n 
B 2 98  LEU 98  98  98  LEU LEU D . n 
B 2 99  PHE 99  99  99  PHE PHE D . n 
B 2 100 ALA 100 100 100 ALA ALA D . n 
B 2 101 LYS 101 101 101 LYS LYS D . n 
B 2 102 GLY 102 102 102 GLY GLY D . n 
B 2 103 TYR 103 103 103 TYR TYR D . n 
B 2 104 TYR 104 104 104 TYR TYR D . n 
B 2 105 SER 105 105 105 SER SER D . n 
B 2 106 TYR 106 106 106 TYR TYR D . n 
B 2 107 GLY 107 107 107 GLY GLY D . n 
B 2 108 THR 108 108 108 THR THR D . n 
B 2 109 ARG 109 109 109 ARG ARG D . n 
B 2 110 PHE 110 110 110 PHE PHE D . n 
B 2 111 MET 111 111 111 MET MET D . n 
B 2 112 GLU 112 112 112 GLU GLU D . n 
B 2 113 GLU 113 113 113 GLU GLU D . n 
B 2 114 ILE 114 114 114 ILE ILE D . n 
B 2 115 MET 115 115 115 MET MET D . n 
B 2 116 ASP 116 116 116 ASP ASP D . n 
B 2 117 LYS 117 117 117 LYS LYS D . n 
B 2 118 ILE 118 118 118 ILE ILE D . n 
B 2 119 GLN 119 119 119 GLN GLN D . n 
B 2 120 LYS 120 120 120 LYS LYS D . n 
B 2 121 GLU 121 121 121 GLU GLU D . n 
B 2 122 VAL 122 122 122 VAL VAL D . n 
B 2 123 ASP 123 123 123 ASP ASP D . n 
B 2 124 GLN 124 124 124 GLN GLN D . n 
B 2 125 THR 125 125 125 THR THR D . n 
B 2 126 GLU 126 126 126 GLU GLU D . n 
B 2 127 HIS 127 127 127 HIS HIS D . n 
B 2 128 LEU 128 128 128 LEU LEU D . n 
B 2 129 GLN 129 129 129 GLN GLN D . n 
B 2 130 GLY 130 130 130 GLY GLY D . n 
B 2 131 PHE 131 131 131 PHE PHE D . n 
B 2 132 ILE 132 132 132 ILE ILE D . n 
B 2 133 VAL 133 133 133 VAL VAL D . n 
B 2 134 VAL 134 134 134 VAL VAL D . n 
B 2 135 HIS 135 135 135 HIS HIS D . n 
B 2 136 SER 136 136 136 SER SER D . n 
B 2 137 ILE 137 137 137 ILE ILE D . n 
B 2 138 GLY 138 138 138 GLY GLY D . n 
B 2 139 ASP 139 139 139 ASP ASP D . n 
B 2 140 GLY 140 140 140 GLY GLY D . n 
B 2 141 THR 141 141 141 THR THR D . n 
B 2 142 GLY 142 142 142 GLY GLY D . n 
B 2 143 ALA 143 143 143 ALA ALA D . n 
B 2 144 GLY 144 144 144 GLY GLY D . n 
B 2 145 LEU 145 145 145 LEU LEU D . n 
B 2 146 ALA 146 146 146 ALA ALA D . n 
B 2 147 PRO 147 147 147 PRO PRO D . n 
B 2 148 LEU 148 148 148 LEU LEU D . n 
B 2 149 ILE 149 149 149 ILE ILE D . n 
B 2 150 MET 150 150 150 MET MET D . n 
B 2 151 GLU 151 151 151 GLU GLU D . n 
B 2 152 ALA 152 152 152 ALA ALA D . n 
B 2 153 ILE 153 153 153 ILE ILE D . n 
B 2 154 LYS 154 154 154 LYS LYS D . n 
B 2 155 LYS 155 155 155 LYS LYS D . n 
B 2 156 LYS 156 156 156 LYS LYS D . n 
B 2 157 HIS 157 157 157 HIS HIS D . n 
B 2 158 PRO 158 158 158 PRO PRO D . n 
B 2 159 LYS 159 159 159 LYS LYS D . n 
B 2 160 LEU 160 160 160 LEU LEU D . n 
B 2 161 VAL 161 161 161 VAL VAL D . n 
B 2 162 MET 162 162 162 MET MET D . n 
B 2 163 MET 163 163 163 MET MET D . n 
B 2 164 SER 164 164 164 SER SER D . n 
B 2 165 TYR 165 165 165 TYR TYR D . n 
B 2 166 SER 166 166 166 SER SER D . n 
B 2 167 ILE 167 167 167 ILE ILE D . n 
B 2 168 VAL 168 168 168 VAL VAL D . n 
B 2 169 PRO 169 169 169 PRO PRO D . n 
B 2 170 SER 170 170 170 SER SER D . n 
B 2 171 GLN 171 171 171 GLN GLN D . n 
B 2 172 ASN 172 172 172 ASN ASN D . n 
B 2 173 MET 173 173 173 MET MET D . n 
B 2 174 ASP 174 174 174 ASP ASP D . n 
B 2 175 CYS 175 175 175 CYS CYS D . n 
B 2 176 SER 176 176 176 SER SER D . n 
B 2 177 THR 177 177 177 THR THR D . n 
B 2 178 ILE 178 178 178 ILE ILE D . n 
B 2 179 LEU 179 179 179 LEU LEU D . n 
B 2 180 PRO 180 180 180 PRO PRO D . n 
B 2 181 TYR 181 181 181 TYR TYR D . n 
B 2 182 ASN 182 182 182 ASN ASN D . n 
B 2 183 ALA 183 183 183 ALA ALA D . n 
B 2 184 ILE 184 184 184 ILE ILE D . n 
B 2 185 LEU 185 185 185 LEU LEU D . n 
B 2 186 SER 186 186 186 SER SER D . n 
B 2 187 LEU 187 187 187 LEU LEU D . n 
B 2 188 ASP 188 188 188 ASP ASP D . n 
B 2 189 LYS 189 189 189 LYS LYS D . n 
B 2 190 LEU 190 190 190 LEU LEU D . n 
B 2 191 THR 191 191 191 THR THR D . n 
B 2 192 SER 192 192 192 SER SER D . n 
B 2 193 CYS 193 193 193 CYS CYS D . n 
B 2 194 ALA 194 194 194 ALA ALA D . n 
B 2 195 ASP 195 195 195 ASP ASP D . n 
B 2 196 ILE 196 196 196 ILE ILE D . n 
B 2 197 SER 197 197 197 SER SER D . n 
B 2 198 MET 198 198 198 MET MET D . n 
B 2 199 ILE 199 199 199 ILE ILE D . n 
B 2 200 ILE 200 200 200 ILE ILE D . n 
B 2 201 ASP 201 201 201 ASP ASP D . n 
B 2 202 ASN 202 202 202 ASN ASN D . n 
B 2 203 ASP 203 203 203 ASP ASP D . n 
B 2 204 SER 204 204 204 SER SER D . n 
B 2 205 ILE 205 205 205 ILE ILE D . n 
B 2 206 TYR 206 206 206 TYR TYR D . n 
B 2 207 ARG 207 207 207 ARG ARG D . n 
B 2 208 ILE 208 208 208 ILE ILE D . n 
B 2 209 VAL 209 209 209 VAL VAL D . n 
B 2 210 ALA 210 210 210 ALA ALA D . n 
B 2 211 THR 211 211 211 THR THR D . n 
B 2 212 GLN 212 212 212 GLN GLN D . n 
B 2 213 GLY 213 213 213 GLY GLY D . n 
B 2 214 LYS 214 214 214 LYS LYS D . n 
B 2 215 GLU 215 215 215 GLU GLU D . n 
B 2 216 ASN 216 216 216 ASN ASN D . n 
B 2 217 GLU 217 217 217 GLU GLU D . n 
B 2 218 LEU 218 218 218 LEU LEU D . n 
B 2 219 SER 219 219 219 SER SER D . n 
B 2 220 GLU 220 220 220 GLU GLU D . n 
B 2 221 SER 221 221 221 SER SER D . n 
B 2 222 ILE 222 222 222 ILE ILE D . n 
B 2 223 PHE 223 223 223 PHE PHE D . n 
B 2 224 ASP 224 224 224 ASP ASP D . n 
B 2 225 GLN 225 225 225 GLN GLN D . n 
B 2 226 VAL 226 226 226 VAL VAL D . n 
B 2 227 LEU 227 227 227 LEU LEU D . n 
B 2 228 ALA 228 228 228 ALA ALA D . n 
B 2 229 LYS 229 229 229 LYS LYS D . n 
B 2 230 ALA 230 230 230 ALA ALA D . n 
B 2 231 LEU 231 231 231 LEU LEU D . n 
B 2 232 VAL 232 232 232 VAL VAL D . n 
B 2 233 GLU 233 233 233 GLU GLU D . n 
B 2 234 ILE 234 234 234 ILE ILE D . n 
B 2 235 THR 235 235 235 THR THR D . n 
B 2 236 ALA 236 236 236 ALA ALA D . n 
B 2 237 THR 237 237 237 THR THR D . n 
B 2 238 LEU 238 238 238 LEU LEU D . n 
B 2 239 ARG 239 239 239 ARG ARG D . n 
B 2 240 PHE 240 240 240 PHE PHE D . n 
B 2 241 ASN 241 241 241 ASN ASN D . n 
B 2 242 SER 242 242 242 SER SER D . n 
B 2 243 PRO 243 243 243 PRO PRO D . n 
B 2 244 LEU 244 244 244 LEU LEU D . n 
B 2 245 ASN 245 245 245 ASN ASN D . n 
B 2 246 ARG 246 246 246 ARG ARG D . n 
B 2 247 SER 247 247 247 SER SER D . n 
B 2 248 MET 248 248 248 MET MET D . n 
B 2 249 MET 249 249 249 MET MET D . n 
B 2 250 GLU 250 250 250 GLU GLU D . n 
B 2 251 MET 251 251 251 MET MET D . n 
B 2 252 SER 252 252 252 SER SER D . n 
B 2 253 THR 253 253 253 THR THR D . n 
B 2 254 ASN 254 254 254 ASN ASN D . n 
B 2 255 LEU 255 255 255 LEU LEU D . n 
B 2 256 VAL 256 256 256 VAL VAL D . n 
B 2 257 PRO 257 257 257 PRO PRO D . n 
B 2 258 PHE 258 258 258 PHE PHE D . n 
B 2 259 PRO 259 259 259 PRO PRO D . n 
B 2 260 ARG 260 260 260 ARG ARG D . n 
B 2 261 ASN 261 261 261 ASN ASN D . n 
B 2 262 HIS 262 262 262 HIS HIS D . n 
B 2 263 PHE 263 263 263 PHE PHE D . n 
B 2 264 LEU 264 264 264 LEU LEU D . n 
B 2 265 MET 265 265 265 MET MET D . n 
B 2 266 THR 266 266 266 THR THR D . n 
B 2 267 SER 267 267 267 SER SER D . n 
B 2 268 MET 268 268 268 MET MET D . n 
B 2 269 SER 269 269 269 SER SER D . n 
B 2 270 PRO 270 270 270 PRO PRO D . n 
B 2 271 LEU 271 271 271 LEU LEU D . n 
B 2 272 GLU 272 272 272 GLU GLU D . n 
B 2 273 THR 273 273 273 THR THR D . n 
B 2 274 SER 274 274 274 SER SER D . n 
B 2 275 LEU 275 275 275 LEU LEU D . n 
B 2 276 THR 276 276 276 THR THR D . n 
B 2 277 SER 277 277 277 SER SER D . n 
B 2 278 ALA 278 278 278 ALA ALA D . n 
B 2 279 HIS 279 279 279 HIS HIS D . n 
B 2 280 GLN 280 280 280 GLN GLN D . n 
B 2 281 LYS 281 281 281 LYS LYS D . n 
B 2 282 ILE 282 282 282 ILE ILE D . n 
B 2 283 GLU 283 283 283 GLU GLU D . n 
B 2 284 THR 284 284 284 THR THR D . n 
B 2 285 LYS 285 285 285 LYS LYS D . n 
B 2 286 GLU 286 286 286 GLU GLU D . n 
B 2 287 LEU 287 287 287 LEU LEU D . n 
B 2 288 MET 288 288 288 MET MET D . n 
B 2 289 GLN 289 289 289 GLN GLN D . n 
B 2 290 ASP 290 290 290 ASP ASP D . n 
B 2 291 LEU 291 291 291 LEU LEU D . n 
B 2 292 ILE 292 292 292 ILE ILE D . n 
B 2 293 ASP 293 293 293 ASP ASP D . n 
B 2 294 GLN 294 294 294 GLN GLN D . n 
B 2 295 ASP 295 295 295 ASP ASP D . n 
B 2 296 HIS 296 296 296 HIS HIS D . n 
B 2 297 ILE 297 297 297 ILE ILE D . n 
B 2 298 LEU 298 298 298 LEU LEU D . n 
B 2 299 ALA 299 299 299 ALA ALA D . n 
B 2 300 PRO 300 300 300 PRO PRO D . n 
B 2 301 ILE 301 301 301 ILE ILE D . n 
B 2 302 THR 302 302 302 THR THR D . n 
B 2 303 VAL 303 303 303 VAL VAL D . n 
B 2 304 GLU 304 304 304 GLU GLU D . n 
B 2 305 LYS 305 305 305 LYS LYS D . n 
B 2 306 GLY 306 306 306 GLY GLY D . n 
B 2 307 VAL 307 307 307 VAL VAL D . n 
B 2 308 PHE 308 308 308 PHE PHE D . n 
B 2 309 THR 309 309 309 THR THR D . n 
B 2 310 ALA 310 310 310 ALA ALA D . n 
B 2 311 PHE 311 311 311 PHE PHE D . n 
B 2 312 VAL 312 312 312 VAL VAL D . n 
B 2 313 ILE 313 313 313 ILE ILE D . n 
B 2 314 ALA 314 314 314 ALA ALA D . n 
B 2 315 LEU 315 315 315 LEU LEU D . n 
B 2 316 ARG 316 316 316 ARG ARG D . n 
B 2 317 GLY 317 317 317 GLY GLY D . n 
B 2 318 GLU 318 318 318 GLU GLU D . n 
B 2 319 ASN 319 319 319 ASN ASN D . n 
B 2 320 PRO 320 320 320 PRO PRO D . n 
B 2 321 HIS 321 321 321 HIS HIS D . n 
B 2 322 SER 322 322 322 SER SER D . n 
B 2 323 ILE 323 323 323 ILE ILE D . n 
B 2 324 LEU 324 324 324 LEU LEU D . n 
B 2 325 GLN 325 325 325 GLN GLN D . n 
B 2 326 ASN 326 326 326 ASN ASN D . n 
B 2 327 SER 327 327 327 SER SER D . n 
B 2 328 ILE 328 328 328 ILE ILE D . n 
B 2 329 LYS 329 329 329 LYS LYS D . n 
B 2 330 GLY 330 330 330 GLY GLY D . n 
B 2 331 PHE 331 331 331 PHE PHE D . n 
B 2 332 GLY 332 332 332 GLY GLY D . n 
B 2 333 ASP 333 333 333 ASP ASP D . n 
B 2 334 ARG 334 334 334 ARG ARG D . n 
B 2 335 VAL 335 335 335 VAL VAL D . n 
B 2 336 LYS 336 336 336 LYS LYS D . n 
B 2 337 PHE 337 337 337 PHE PHE D . n 
B 2 338 SER 338 338 338 SER SER D . n 
B 2 339 GLU 339 339 339 GLU GLU D . n 
B 2 340 ILE 340 340 340 ILE ILE D . n 
B 2 341 PHE 341 341 341 PHE PHE D . n 
B 2 342 PRO 342 342 342 PRO PRO D . n 
B 2 343 THR 343 343 343 THR THR D . n 
B 2 344 ALA 344 344 344 ALA ALA D . n 
B 2 345 ILE 345 345 345 ILE ILE D . n 
B 2 346 LYS 346 346 346 LYS LYS D . n 
B 2 347 ALA 347 347 347 ALA ALA D . n 
B 2 348 ASP 348 348 348 ASP ASP D . n 
B 2 349 SER 349 349 349 SER SER D . n 
B 2 350 THR 350 350 350 THR THR D . n 
B 2 351 THR 351 351 351 THR THR D . n 
B 2 352 LEU 352 352 352 LEU LEU D . n 
B 2 353 THR 353 353 353 THR THR D . n 
B 2 354 ASP 354 354 354 ASP ASP D . n 
B 2 355 GLU 355 355 355 GLU GLU D . n 
B 2 356 LYS 356 356 356 LYS LYS D . n 
B 2 357 LEU 357 357 357 LEU LEU D . n 
B 2 358 ALA 358 358 358 ALA ALA D . n 
B 2 359 ARG 359 359 359 ARG ARG D . n 
B 2 360 SER 360 360 360 SER SER D . n 
B 2 361 GLY 361 361 361 GLY GLY D . n 
B 2 362 ILE 362 362 362 ILE ILE D . n 
B 2 363 THR 363 363 363 THR THR D . n 
B 2 364 LEU 364 364 364 LEU LEU D . n 
B 2 365 MET 365 365 365 MET MET D . n 
B 2 366 ASN 366 366 366 ASN ASN D . n 
B 2 367 HIS 367 367 367 HIS HIS D . n 
B 2 368 SER 368 368 368 SER SER D . n 
B 2 369 GLY 369 369 369 GLY GLY D . n 
B 2 370 VAL 370 370 370 VAL VAL D . n 
B 2 371 ALA 371 371 371 ALA ALA D . n 
B 2 372 ASN 372 372 372 ASN ASN D . n 
B 2 373 LEU 373 373 373 LEU LEU D . n 
B 2 374 PHE 374 374 374 PHE PHE D . n 
B 2 375 GLN 375 375 375 GLN GLN D . n 
B 2 376 PHE 376 376 376 PHE PHE D . n 
B 2 377 LEU 377 377 377 LEU LEU D . n 
B 2 378 LEU 378 378 378 LEU LEU D . n 
B 2 379 THR 379 379 379 THR THR D . n 
B 2 380 GLN 380 380 380 GLN GLN D . n 
B 2 381 PHE 381 381 381 PHE PHE D . n 
B 2 382 GLU 382 382 382 GLU GLU D . n 
B 2 383 LEU 383 383 383 LEU LEU D . n 
B 2 384 MET 384 384 384 MET MET D . n 
B 2 385 TYR 385 385 385 TYR TYR D . n 
B 2 386 ASP 386 386 386 ASP ASP D . n 
B 2 387 HIS 387 387 387 HIS HIS D . n 
B 2 388 ASP 388 388 388 ASP ASP D . n 
B 2 389 ALA 389 389 389 ALA ALA D . n 
B 2 390 PHE 390 390 390 PHE PHE D . n 
B 2 391 THR 391 391 391 THR THR D . n 
B 2 392 THR 392 392 392 THR THR D . n 
B 2 393 TRP 393 393 393 TRP TRP D . n 
B 2 394 TYR 394 394 394 TYR TYR D . n 
B 2 395 TYR 395 395 395 TYR TYR D . n 
B 2 396 GLN 396 396 396 GLN GLN D . n 
B 2 397 GLU 397 397 397 GLU GLU D . n 
B 2 398 GLY 398 398 398 GLY GLY D . n 
B 2 399 MET 399 399 399 MET MET D . n 
B 2 400 GLN 400 400 400 GLN GLN D . n 
B 2 401 PRO 401 401 401 PRO PRO D . n 
B 2 402 SER 402 402 402 SER SER D . n 
B 2 403 GLU 403 403 403 GLU GLU D . n 
B 2 404 PHE 404 404 404 PHE PHE D . n 
B 2 405 GLU 405 405 405 GLU GLU D . n 
B 2 406 ALA 406 406 406 ALA ALA D . n 
B 2 407 ALA 407 407 407 ALA ALA D . n 
B 2 408 LYS 408 408 408 LYS LYS D . n 
B 2 409 ASN 409 409 409 ASN ASN D . n 
B 2 410 ASN 410 410 410 ASN ASN D . n 
B 2 411 ILE 411 411 411 ILE ILE D . n 
B 2 412 GLN 412 412 412 GLN GLN D . n 
B 2 413 LYS 413 413 413 LYS LYS D . n 
B 2 414 LEU 414 414 414 LEU LEU D . n 
B 2 415 ILE 415 415 415 ILE ILE D . n 
B 2 416 THR 416 416 416 THR THR D . n 
B 2 417 GLU 417 417 417 GLU GLU D . n 
B 2 418 TYR 418 418 418 TYR TYR D . n 
B 2 419 LYS 419 419 419 LYS LYS D . n 
B 2 420 GLN 420 420 420 GLN GLN D . n 
B 2 421 ASP 421 421 421 ASP ASP D . n 
B 2 422 GLU 422 422 422 GLU GLU D . n 
B 2 423 TYR 423 423 423 TYR TYR D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        GTP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   GTP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         C 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          GTP 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    501 
_pdbx_nonpoly_scheme.pdb_mon_id      GTP 
_pdbx_nonpoly_scheme.auth_mon_id     GTP 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9F6V 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9F6V 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9F6V 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9F6V 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.023  ? 6739 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 1.537  ? 9123 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 11.245 ? 2483 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.095  ? 1039 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.008  ? 1168 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9F6V 
_struct.title                        'cryoEM structure of Asgard tubulin heterodimer AtubA/B2 with GTP' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9F6V 
_struct_keywords.text            'cryoEM, tubulin, Asgard archaea, microtubule, CYTOSOLIC PROTEIN' 
_struct_keywords.pdbx_keywords   'CYTOSOLIC PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9F6V 9F6V ? 1 ? 1 
2 PDB 9F6V 9F6V ? 2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9F6V A 1 ? 423 ? 9F6V 1 ? 423 ? 1 423 
2 2 9F6V D 1 ? 423 ? 9F6V 1 ? 423 ? 1 423 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 11  ? HIS A 29  ? GLY A 11  HIS A 29  1 ? 19 
HELX_P HELX_P2  AA2 ASP A 44  ? ILE A 47  ? ASP A 44  ILE A 47  5 ? 4  
HELX_P HELX_P3  AA3 GLU A 66  ? ASN A 72  ? GLU A 66  ASN A 72  1 ? 7  
HELX_P HELX_P4  AA4 ASN A 72  ? PHE A 77  ? ASN A 72  PHE A 77  1 ? 6  
HELX_P HELX_P5  AA5 GLY A 78  ? PHE A 81  ? GLY A 78  PHE A 81  5 ? 4  
HELX_P HELX_P6  AA6 ASP A 82  ? LYS A 84  ? ASP A 82  LYS A 84  5 ? 3  
HELX_P HELX_P7  AA7 ASN A 96  ? GLU A 103 ? ASN A 96  GLU A 103 1 ? 8  
HELX_P HELX_P8  AA8 GLY A 105 ? GLU A 122 ? GLY A 105 GLU A 122 1 ? 18 
HELX_P HELX_P9  AA9 GLY A 138 ? TYR A 155 ? GLY A 138 TYR A 155 1 ? 18 
HELX_P HELX_P10 AB1 VAL A 176 ? ALA A 192 ? VAL A 176 ALA A 192 1 ? 17 
HELX_P HELX_P11 AB2 ASN A 200 ? LYS A 210 ? ASN A 200 LYS A 210 1 ? 11 
HELX_P HELX_P12 AB3 SER A 217 ? ALA A 234 ? SER A 217 ALA A 234 1 ? 18 
HELX_P HELX_P13 AB4 SER A 235 ? ARG A 237 ? SER A 235 ARG A 237 5 ? 3  
HELX_P HELX_P14 AB5 ASP A 245 ? VAL A 254 ? ASP A 245 VAL A 254 1 ? 10 
HELX_P HELX_P15 AB6 THR A 281 ? PHE A 290 ? THR A 281 PHE A 290 1 ? 10 
HELX_P HELX_P16 AB7 LYS A 300 ? GLY A 304 ? LYS A 300 GLY A 304 5 ? 5  
HELX_P HELX_P17 AB8 LYS A 318 ? ASN A 333 ? LYS A 318 ASN A 333 1 ? 16 
HELX_P HELX_P18 AB9 ILE A 368 ? SER A 384 ? ILE A 368 SER A 384 1 ? 17 
HELX_P HELX_P19 AC1 PHE A 388 ? SER A 395 ? PHE A 388 SER A 395 1 ? 8  
HELX_P HELX_P20 AC2 GLU A 398 ? THR A 420 ? GLU A 398 THR A 420 1 ? 23 
HELX_P HELX_P21 AC3 GLY B 11  ? HIS B 29  ? GLY D 11  HIS D 29  1 ? 19 
HELX_P HELX_P22 AC4 VAL B 44  ? ASN B 47  ? VAL D 44  ASN D 47  5 ? 4  
HELX_P HELX_P23 AC5 PRO B 68  ? LYS B 77  ? PRO D 68  LYS D 77  1 ? 10 
HELX_P HELX_P24 AC6 ASP B 84  ? LYS B 86  ? ASP D 84  LYS D 86  5 ? 3  
HELX_P HELX_P25 AC7 LEU B 98  ? TYR B 104 ? LEU D 98  TYR D 104 1 ? 7  
HELX_P HELX_P26 AC8 TYR B 106 ? ARG B 109 ? TYR D 106 ARG D 109 5 ? 4  
HELX_P HELX_P27 AC9 PHE B 110 ? ASP B 123 ? PHE D 110 ASP D 123 1 ? 14 
HELX_P HELX_P28 AD1 ASP B 139 ? LYS B 155 ? ASP D 139 LYS D 155 1 ? 17 
HELX_P HELX_P29 AD2 ILE B 178 ? THR B 191 ? ILE D 178 THR D 191 1 ? 14 
HELX_P HELX_P30 AD3 ASN B 202 ? GLN B 212 ? ASN D 202 GLN D 212 1 ? 11 
HELX_P HELX_P31 AD4 LYS B 214 ? LEU B 218 ? LYS D 214 LEU D 218 5 ? 5  
HELX_P HELX_P32 AD5 SER B 219 ? THR B 237 ? SER D 219 THR D 237 1 ? 19 
HELX_P HELX_P33 AD6 SER B 247 ? VAL B 256 ? SER D 247 VAL D 256 1 ? 10 
HELX_P HELX_P34 AD7 GLU B 272 ? THR B 276 ? GLU D 272 THR D 276 5 ? 5  
HELX_P HELX_P35 AD8 GLU B 283 ? ASP B 293 ? GLU D 283 ASP D 293 1 ? 11 
HELX_P HELX_P36 AD9 GLN B 294 ? ILE B 297 ? GLN D 294 ILE D 297 5 ? 4  
HELX_P HELX_P37 AE1 PRO B 320 ? ILE B 328 ? PRO D 320 ILE D 328 1 ? 9  
HELX_P HELX_P38 AE2 LYS B 329 ? GLY B 332 ? LYS D 329 GLY D 332 5 ? 4  
HELX_P HELX_P39 AE3 GLY B 369 ? ASP B 386 ? GLY D 369 ASP D 386 1 ? 18 
HELX_P HELX_P40 AE4 THR B 391 ? GLN B 396 ? THR D 391 GLN D 396 1 ? 6  
HELX_P HELX_P41 AE5 PRO B 401 ? ASP B 421 ? PRO D 401 ASP D 421 1 ? 21 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ALA 267 A . ? ALA 267 A PRO 268 A ? PRO 268 A 1 -2.97 
2 SER 269 B . ? SER 269 D PRO 270 B ? PRO 270 D 1 -3.21 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 10 ? 
AA2 ? 2  ? 
AA3 ? 10 ? 
AA4 ? 2  ? 
AA5 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? parallel      
AA1 2 3  ? parallel      
AA1 3 4  ? parallel      
AA1 4 5  ? parallel      
AA1 5 6  ? parallel      
AA1 6 7  ? parallel      
AA1 7 8  ? anti-parallel 
AA1 8 9  ? anti-parallel 
AA1 9 10 ? parallel      
AA2 1 2  ? anti-parallel 
AA3 1 2  ? parallel      
AA3 2 3  ? parallel      
AA3 3 4  ? parallel      
AA3 4 5  ? parallel      
AA3 5 6  ? parallel      
AA3 6 7  ? parallel      
AA3 7 8  ? anti-parallel 
AA3 8 9  ? anti-parallel 
AA3 9 10 ? parallel      
AA4 1 2  ? anti-parallel 
AA5 1 2  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  ILE A 86  ? VAL A 87  ? ILE A 86  VAL A 87  
AA1 2  ALA A 60  ? VAL A 63  ? ALA A 60  VAL A 63  
AA1 3  GLU A 4   ? VAL A 10  ? GLU A 4   VAL A 10  
AA1 4  ILE A 126 ? SER A 134 ? ILE A 126 SER A 134 
AA1 5  ILE A 160 ? PHE A 166 ? ILE A 160 PHE A 166 
AA1 6  CYS A 194 ? ASP A 199 ? CYS A 194 ASP A 199 
AA1 7  PHE A 261 ? ALA A 267 ? PHE A 261 ALA A 267 
AA1 8  LEU A 357 ? ASN A 365 ? LEU A 357 ASN A 365 
AA1 9  TYR A 306 ? GLY A 315 ? TYR A 306 GLY A 315 
AA1 10 PHE A 343 ? SER A 348 ? PHE A 343 SER A 348 
AA2 1  PHE A 49  ? ILE A 52  ? PHE A 49  ILE A 52  
AA2 2  LYS A 55  ? PRO A 58  ? LYS A 55  PRO A 58  
AA3 1  CYS B 88  ? MET B 90  ? CYS D 88  MET D 90  
AA3 2  THR B 61  ? ASP B 65  ? THR D 61  ASP D 65  
AA3 3  GLU B 4   ? VAL B 10  ? GLU D 4   VAL D 10  
AA3 4  LEU B 128 ? SER B 136 ? LEU D 128 SER D 136 
AA3 5  VAL B 161 ? VAL B 168 ? VAL D 161 VAL D 168 
AA3 6  ILE B 196 ? ASP B 201 ? ILE D 196 ASP D 201 
AA3 7  PHE B 263 ? SER B 269 ? PHE D 263 SER D 269 
AA3 8  ARG B 359 ? HIS B 367 ? ARG D 359 HIS D 367 
AA3 9  PHE B 308 ? GLY B 317 ? PHE D 308 GLY D 317 
AA3 10 LYS B 346 ? THR B 350 ? LYS D 346 THR D 350 
AA4 1  ILE B 31  ? ASP B 32  ? ILE D 31  ASP D 32  
AA4 2  GLN B 36  ? GLU B 37  ? GLN D 36  GLU D 37  
AA5 1  PHE B 49  ? LYS B 51  ? PHE D 49  LYS D 51  
AA5 2  TRP B 57  ? PRO B 59  ? TRP D 57  PRO D 59  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  O VAL A 87  ? O VAL A 87  N VAL A 62  ? N VAL A 62  
AA1 2 3  O VAL A 61  ? O VAL A 61  N GLN A 9   ? N GLN A 9   
AA1 3 4  N GLU A 4   ? N GLU A 4   O GLY A 127 ? O GLY A 127 
AA1 4 5  N LEU A 131 ? N LEU A 131 O PHE A 163 ? O PHE A 163 
AA1 5 6  N THR A 162 ? N THR A 162 O ILE A 196 ? O ILE A 196 
AA1 6 7  N SER A 195 ? N SER A 195 O LEU A 262 ? O LEU A 262 
AA1 7 8  N SER A 265 ? N SER A 265 O MET A 361 ? O MET A 361 
AA1 8 9  O GLY A 358 ? O GLY A 358 N ARG A 314 ? N ARG A 314 
AA1 9 10 N VAL A 311 ? N VAL A 311 O LYS A 344 ? O LYS A 344 
AA2 1 2  N ASN A 50  ? N ASN A 50  O ILE A 57  ? O ILE A 57  
AA3 1 2  O VAL B 89  ? O VAL D 89  N LEU B 63  ? N LEU D 63  
AA3 2 3  O VAL B 64  ? O VAL D 64  N HIS B 9   ? N HIS D 9   
AA3 3 4  N GLU B 4   ? N GLU D 4   O GLN B 129 ? O GLN D 129 
AA3 4 5  N PHE B 131 ? N PHE D 131 O MET B 163 ? O MET D 163 
AA3 5 6  N SER B 166 ? N SER D 166 O MET B 198 ? O MET D 198 
AA3 6 7  N SER B 197 ? N SER D 197 O LEU B 264 ? O LEU D 264 
AA3 7 8  N MET B 265 ? N MET D 265 O MET B 365 ? O MET D 365 
AA3 8 9  O SER B 360 ? O SER D 360 N ARG B 316 ? N ARG D 316 
AA3 9 10 N ILE B 313 ? N ILE D 313 O LYS B 346 ? O LYS D 346 
AA4 1 2  N ASP B 32  ? N ASP D 32  O GLN B 36  ? O GLN D 36  
AA5 1 2  N GLU B 50  ? N GLU D 50  O ILE B 58  ? O ILE D 58  
# 
_pdbx_entry_details.entry_id                   9F6V 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CB  A TYR 56  ? ? CG  A TYR 56  ? ? 1.416 1.512 -0.096 0.015 N 
2 1 CB  A TRP 338 ? ? CG  A TRP 338 ? ? 1.290 1.498 -0.208 0.018 N 
3 1 CB  A ASN 364 ? ? CG  A ASN 364 ? ? 1.338 1.506 -0.168 0.023 N 
4 1 CB  D CYS 175 ? ? SG  D CYS 175 ? ? 1.706 1.812 -0.106 0.016 N 
5 1 CG  D TYR 181 ? ? CD2 D TYR 181 ? ? 1.308 1.387 -0.079 0.013 N 
6 1 CE2 D TYR 181 ? ? CD2 D TYR 181 ? ? 1.295 1.389 -0.094 0.015 N 
7 1 CE2 D TRP 393 ? ? CD2 D TRP 393 ? ? 1.336 1.409 -0.073 0.012 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CB D ASP 203 ? ? CG D ASP 203 ? ? OD1 D ASP 203 ? ? 123.83 118.30 5.53 0.90 N 
2 1 CB D PHE 311 ? ? CG D PHE 311 ? ? CD1 D PHE 311 ? ? 125.50 120.80 4.70 0.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ILE A 39  ? ? -103.32 -61.76  
2  1 ASP A 40  ? ? -162.56 94.13   
3  1 ALA A 90  ? ? 52.12   -137.59 
4  1 ASN A 96  ? ? -165.94 112.93  
5  1 SER A 239 ? ? 59.74   -129.47 
6  1 GLU A 278 ? ? 46.16   -129.94 
7  1 THR A 341 ? ? -130.57 -154.79 
8  1 PHE A 388 ? ? -142.80 59.93   
9  1 TYR D 33  ? ? 60.37   -41.17  
10 1 PHE D 82  ? ? -130.68 -62.96  
11 1 MET D 173 ? ? -121.56 -160.60 
12 1 PRO D 259 ? ? -38.83  -33.73  
13 1 LEU D 298 ? ? -92.82  58.78   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9F6V 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9F6V 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.5 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               71198 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            6.8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Asgard tubulin heterodimer AtubA/B2 from Candidatus Lokiarchaeum ossiferum' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        9F6V 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        UltrAuFoil 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9F6V 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE-PROPANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9F6V 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A MET 1 ? A MET 1 
2 1 Y 1 D MET 1 ? B MET 1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
GLN N      N N N 88  
GLN CA     C N S 89  
GLN C      C N N 90  
GLN O      O N N 91  
GLN CB     C N N 92  
GLN CG     C N N 93  
GLN CD     C N N 94  
GLN OE1    O N N 95  
GLN NE2    N N N 96  
GLN OXT    O N N 97  
GLN H      H N N 98  
GLN H2     H N N 99  
GLN HA     H N N 100 
GLN HB2    H N N 101 
GLN HB3    H N N 102 
GLN HG2    H N N 103 
GLN HG3    H N N 104 
GLN HE21   H N N 105 
GLN HE22   H N N 106 
GLN HXT    H N N 107 
GLU N      N N N 108 
GLU CA     C N S 109 
GLU C      C N N 110 
GLU O      O N N 111 
GLU CB     C N N 112 
GLU CG     C N N 113 
GLU CD     C N N 114 
GLU OE1    O N N 115 
GLU OE2    O N N 116 
GLU OXT    O N N 117 
GLU H      H N N 118 
GLU H2     H N N 119 
GLU HA     H N N 120 
GLU HB2    H N N 121 
GLU HB3    H N N 122 
GLU HG2    H N N 123 
GLU HG3    H N N 124 
GLU HE2    H N N 125 
GLU HXT    H N N 126 
GLY N      N N N 127 
GLY CA     C N N 128 
GLY C      C N N 129 
GLY O      O N N 130 
GLY OXT    O N N 131 
GLY H      H N N 132 
GLY H2     H N N 133 
GLY HA2    H N N 134 
GLY HA3    H N N 135 
GLY HXT    H N N 136 
GTP PG     P N N 137 
GTP O1G    O N N 138 
GTP O2G    O N N 139 
GTP O3G    O N N 140 
GTP O3B    O N N 141 
GTP PB     P N N 142 
GTP O1B    O N N 143 
GTP O2B    O N N 144 
GTP O3A    O N N 145 
GTP PA     P N N 146 
GTP O1A    O N N 147 
GTP O2A    O N N 148 
GTP "O5'"  O N N 149 
GTP "C5'"  C N N 150 
GTP "C4'"  C N R 151 
GTP "O4'"  O N N 152 
GTP "C3'"  C N S 153 
GTP "O3'"  O N N 154 
GTP "C2'"  C N R 155 
GTP "O2'"  O N N 156 
GTP "C1'"  C N R 157 
GTP N9     N Y N 158 
GTP C8     C Y N 159 
GTP N7     N Y N 160 
GTP C5     C Y N 161 
GTP C6     C N N 162 
GTP O6     O N N 163 
GTP N1     N N N 164 
GTP C2     C N N 165 
GTP N2     N N N 166 
GTP N3     N N N 167 
GTP C4     C Y N 168 
GTP HOG2   H N N 169 
GTP HOG3   H N N 170 
GTP HOB2   H N N 171 
GTP HOA2   H N N 172 
GTP "H5'"  H N N 173 
GTP "H5''" H N N 174 
GTP "H4'"  H N N 175 
GTP "H3'"  H N N 176 
GTP "HO3'" H N N 177 
GTP "H2'"  H N N 178 
GTP "HO2'" H N N 179 
GTP "H1'"  H N N 180 
GTP H8     H N N 181 
GTP HN1    H N N 182 
GTP HN21   H N N 183 
GTP HN22   H N N 184 
HIS N      N N N 185 
HIS CA     C N S 186 
HIS C      C N N 187 
HIS O      O N N 188 
HIS CB     C N N 189 
HIS CG     C Y N 190 
HIS ND1    N Y N 191 
HIS CD2    C Y N 192 
HIS CE1    C Y N 193 
HIS NE2    N Y N 194 
HIS OXT    O N N 195 
HIS H      H N N 196 
HIS H2     H N N 197 
HIS HA     H N N 198 
HIS HB2    H N N 199 
HIS HB3    H N N 200 
HIS HD1    H N N 201 
HIS HD2    H N N 202 
HIS HE1    H N N 203 
HIS HE2    H N N 204 
HIS HXT    H N N 205 
ILE N      N N N 206 
ILE CA     C N S 207 
ILE C      C N N 208 
ILE O      O N N 209 
ILE CB     C N S 210 
ILE CG1    C N N 211 
ILE CG2    C N N 212 
ILE CD1    C N N 213 
ILE OXT    O N N 214 
ILE H      H N N 215 
ILE H2     H N N 216 
ILE HA     H N N 217 
ILE HB     H N N 218 
ILE HG12   H N N 219 
ILE HG13   H N N 220 
ILE HG21   H N N 221 
ILE HG22   H N N 222 
ILE HG23   H N N 223 
ILE HD11   H N N 224 
ILE HD12   H N N 225 
ILE HD13   H N N 226 
ILE HXT    H N N 227 
LEU N      N N N 228 
LEU CA     C N S 229 
LEU C      C N N 230 
LEU O      O N N 231 
LEU CB     C N N 232 
LEU CG     C N N 233 
LEU CD1    C N N 234 
LEU CD2    C N N 235 
LEU OXT    O N N 236 
LEU H      H N N 237 
LEU H2     H N N 238 
LEU HA     H N N 239 
LEU HB2    H N N 240 
LEU HB3    H N N 241 
LEU HG     H N N 242 
LEU HD11   H N N 243 
LEU HD12   H N N 244 
LEU HD13   H N N 245 
LEU HD21   H N N 246 
LEU HD22   H N N 247 
LEU HD23   H N N 248 
LEU HXT    H N N 249 
LYS N      N N N 250 
LYS CA     C N S 251 
LYS C      C N N 252 
LYS O      O N N 253 
LYS CB     C N N 254 
LYS CG     C N N 255 
LYS CD     C N N 256 
LYS CE     C N N 257 
LYS NZ     N N N 258 
LYS OXT    O N N 259 
LYS H      H N N 260 
LYS H2     H N N 261 
LYS HA     H N N 262 
LYS HB2    H N N 263 
LYS HB3    H N N 264 
LYS HG2    H N N 265 
LYS HG3    H N N 266 
LYS HD2    H N N 267 
LYS HD3    H N N 268 
LYS HE2    H N N 269 
LYS HE3    H N N 270 
LYS HZ1    H N N 271 
LYS HZ2    H N N 272 
LYS HZ3    H N N 273 
LYS HXT    H N N 274 
MET N      N N N 275 
MET CA     C N S 276 
MET C      C N N 277 
MET O      O N N 278 
MET CB     C N N 279 
MET CG     C N N 280 
MET SD     S N N 281 
MET CE     C N N 282 
MET OXT    O N N 283 
MET H      H N N 284 
MET H2     H N N 285 
MET HA     H N N 286 
MET HB2    H N N 287 
MET HB3    H N N 288 
MET HG2    H N N 289 
MET HG3    H N N 290 
MET HE1    H N N 291 
MET HE2    H N N 292 
MET HE3    H N N 293 
MET HXT    H N N 294 
PHE N      N N N 295 
PHE CA     C N S 296 
PHE C      C N N 297 
PHE O      O N N 298 
PHE CB     C N N 299 
PHE CG     C Y N 300 
PHE CD1    C Y N 301 
PHE CD2    C Y N 302 
PHE CE1    C Y N 303 
PHE CE2    C Y N 304 
PHE CZ     C Y N 305 
PHE OXT    O N N 306 
PHE H      H N N 307 
PHE H2     H N N 308 
PHE HA     H N N 309 
PHE HB2    H N N 310 
PHE HB3    H N N 311 
PHE HD1    H N N 312 
PHE HD2    H N N 313 
PHE HE1    H N N 314 
PHE HE2    H N N 315 
PHE HZ     H N N 316 
PHE HXT    H N N 317 
PRO N      N N N 318 
PRO CA     C N S 319 
PRO C      C N N 320 
PRO O      O N N 321 
PRO CB     C N N 322 
PRO CG     C N N 323 
PRO CD     C N N 324 
PRO OXT    O N N 325 
PRO H      H N N 326 
PRO HA     H N N 327 
PRO HB2    H N N 328 
PRO HB3    H N N 329 
PRO HG2    H N N 330 
PRO HG3    H N N 331 
PRO HD2    H N N 332 
PRO HD3    H N N 333 
PRO HXT    H N N 334 
SER N      N N N 335 
SER CA     C N S 336 
SER C      C N N 337 
SER O      O N N 338 
SER CB     C N N 339 
SER OG     O N N 340 
SER OXT    O N N 341 
SER H      H N N 342 
SER H2     H N N 343 
SER HA     H N N 344 
SER HB2    H N N 345 
SER HB3    H N N 346 
SER HG     H N N 347 
SER HXT    H N N 348 
THR N      N N N 349 
THR CA     C N S 350 
THR C      C N N 351 
THR O      O N N 352 
THR CB     C N R 353 
THR OG1    O N N 354 
THR CG2    C N N 355 
THR OXT    O N N 356 
THR H      H N N 357 
THR H2     H N N 358 
THR HA     H N N 359 
THR HB     H N N 360 
THR HG1    H N N 361 
THR HG21   H N N 362 
THR HG22   H N N 363 
THR HG23   H N N 364 
THR HXT    H N N 365 
TRP N      N N N 366 
TRP CA     C N S 367 
TRP C      C N N 368 
TRP O      O N N 369 
TRP CB     C N N 370 
TRP CG     C Y N 371 
TRP CD1    C Y N 372 
TRP CD2    C Y N 373 
TRP NE1    N Y N 374 
TRP CE2    C Y N 375 
TRP CE3    C Y N 376 
TRP CZ2    C Y N 377 
TRP CZ3    C Y N 378 
TRP CH2    C Y N 379 
TRP OXT    O N N 380 
TRP H      H N N 381 
TRP H2     H N N 382 
TRP HA     H N N 383 
TRP HB2    H N N 384 
TRP HB3    H N N 385 
TRP HD1    H N N 386 
TRP HE1    H N N 387 
TRP HE3    H N N 388 
TRP HZ2    H N N 389 
TRP HZ3    H N N 390 
TRP HH2    H N N 391 
TRP HXT    H N N 392 
TYR N      N N N 393 
TYR CA     C N S 394 
TYR C      C N N 395 
TYR O      O N N 396 
TYR CB     C N N 397 
TYR CG     C Y N 398 
TYR CD1    C Y N 399 
TYR CD2    C Y N 400 
TYR CE1    C Y N 401 
TYR CE2    C Y N 402 
TYR CZ     C Y N 403 
TYR OH     O N N 404 
TYR OXT    O N N 405 
TYR H      H N N 406 
TYR H2     H N N 407 
TYR HA     H N N 408 
TYR HB2    H N N 409 
TYR HB3    H N N 410 
TYR HD1    H N N 411 
TYR HD2    H N N 412 
TYR HE1    H N N 413 
TYR HE2    H N N 414 
TYR HH     H N N 415 
TYR HXT    H N N 416 
VAL N      N N N 417 
VAL CA     C N S 418 
VAL C      C N N 419 
VAL O      O N N 420 
VAL CB     C N N 421 
VAL CG1    C N N 422 
VAL CG2    C N N 423 
VAL OXT    O N N 424 
VAL H      H N N 425 
VAL H2     H N N 426 
VAL HA     H N N 427 
VAL HB     H N N 428 
VAL HG11   H N N 429 
VAL HG12   H N N 430 
VAL HG13   H N N 431 
VAL HG21   H N N 432 
VAL HG22   H N N 433 
VAL HG23   H N N 434 
VAL HXT    H N N 435 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
GLN N     CA     sing N N 83  
GLN N     H      sing N N 84  
GLN N     H2     sing N N 85  
GLN CA    C      sing N N 86  
GLN CA    CB     sing N N 87  
GLN CA    HA     sing N N 88  
GLN C     O      doub N N 89  
GLN C     OXT    sing N N 90  
GLN CB    CG     sing N N 91  
GLN CB    HB2    sing N N 92  
GLN CB    HB3    sing N N 93  
GLN CG    CD     sing N N 94  
GLN CG    HG2    sing N N 95  
GLN CG    HG3    sing N N 96  
GLN CD    OE1    doub N N 97  
GLN CD    NE2    sing N N 98  
GLN NE2   HE21   sing N N 99  
GLN NE2   HE22   sing N N 100 
GLN OXT   HXT    sing N N 101 
GLU N     CA     sing N N 102 
GLU N     H      sing N N 103 
GLU N     H2     sing N N 104 
GLU CA    C      sing N N 105 
GLU CA    CB     sing N N 106 
GLU CA    HA     sing N N 107 
GLU C     O      doub N N 108 
GLU C     OXT    sing N N 109 
GLU CB    CG     sing N N 110 
GLU CB    HB2    sing N N 111 
GLU CB    HB3    sing N N 112 
GLU CG    CD     sing N N 113 
GLU CG    HG2    sing N N 114 
GLU CG    HG3    sing N N 115 
GLU CD    OE1    doub N N 116 
GLU CD    OE2    sing N N 117 
GLU OE2   HE2    sing N N 118 
GLU OXT   HXT    sing N N 119 
GLY N     CA     sing N N 120 
GLY N     H      sing N N 121 
GLY N     H2     sing N N 122 
GLY CA    C      sing N N 123 
GLY CA    HA2    sing N N 124 
GLY CA    HA3    sing N N 125 
GLY C     O      doub N N 126 
GLY C     OXT    sing N N 127 
GLY OXT   HXT    sing N N 128 
GTP PG    O1G    doub N N 129 
GTP PG    O2G    sing N N 130 
GTP PG    O3G    sing N N 131 
GTP PG    O3B    sing N N 132 
GTP O2G   HOG2   sing N N 133 
GTP O3G   HOG3   sing N N 134 
GTP O3B   PB     sing N N 135 
GTP PB    O1B    doub N N 136 
GTP PB    O2B    sing N N 137 
GTP PB    O3A    sing N N 138 
GTP O2B   HOB2   sing N N 139 
GTP O3A   PA     sing N N 140 
GTP PA    O1A    doub N N 141 
GTP PA    O2A    sing N N 142 
GTP PA    "O5'"  sing N N 143 
GTP O2A   HOA2   sing N N 144 
GTP "O5'" "C5'"  sing N N 145 
GTP "C5'" "C4'"  sing N N 146 
GTP "C5'" "H5'"  sing N N 147 
GTP "C5'" "H5''" sing N N 148 
GTP "C4'" "O4'"  sing N N 149 
GTP "C4'" "C3'"  sing N N 150 
GTP "C4'" "H4'"  sing N N 151 
GTP "O4'" "C1'"  sing N N 152 
GTP "C3'" "O3'"  sing N N 153 
GTP "C3'" "C2'"  sing N N 154 
GTP "C3'" "H3'"  sing N N 155 
GTP "O3'" "HO3'" sing N N 156 
GTP "C2'" "O2'"  sing N N 157 
GTP "C2'" "C1'"  sing N N 158 
GTP "C2'" "H2'"  sing N N 159 
GTP "O2'" "HO2'" sing N N 160 
GTP "C1'" N9     sing N N 161 
GTP "C1'" "H1'"  sing N N 162 
GTP N9    C8     sing Y N 163 
GTP N9    C4     sing Y N 164 
GTP C8    N7     doub Y N 165 
GTP C8    H8     sing N N 166 
GTP N7    C5     sing Y N 167 
GTP C5    C6     sing N N 168 
GTP C5    C4     doub Y N 169 
GTP C6    O6     doub N N 170 
GTP C6    N1     sing N N 171 
GTP N1    C2     sing N N 172 
GTP N1    HN1    sing N N 173 
GTP C2    N2     sing N N 174 
GTP C2    N3     doub N N 175 
GTP N2    HN21   sing N N 176 
GTP N2    HN22   sing N N 177 
GTP N3    C4     sing N N 178 
HIS N     CA     sing N N 179 
HIS N     H      sing N N 180 
HIS N     H2     sing N N 181 
HIS CA    C      sing N N 182 
HIS CA    CB     sing N N 183 
HIS CA    HA     sing N N 184 
HIS C     O      doub N N 185 
HIS C     OXT    sing N N 186 
HIS CB    CG     sing N N 187 
HIS CB    HB2    sing N N 188 
HIS CB    HB3    sing N N 189 
HIS CG    ND1    sing Y N 190 
HIS CG    CD2    doub Y N 191 
HIS ND1   CE1    doub Y N 192 
HIS ND1   HD1    sing N N 193 
HIS CD2   NE2    sing Y N 194 
HIS CD2   HD2    sing N N 195 
HIS CE1   NE2    sing Y N 196 
HIS CE1   HE1    sing N N 197 
HIS NE2   HE2    sing N N 198 
HIS OXT   HXT    sing N N 199 
ILE N     CA     sing N N 200 
ILE N     H      sing N N 201 
ILE N     H2     sing N N 202 
ILE CA    C      sing N N 203 
ILE CA    CB     sing N N 204 
ILE CA    HA     sing N N 205 
ILE C     O      doub N N 206 
ILE C     OXT    sing N N 207 
ILE CB    CG1    sing N N 208 
ILE CB    CG2    sing N N 209 
ILE CB    HB     sing N N 210 
ILE CG1   CD1    sing N N 211 
ILE CG1   HG12   sing N N 212 
ILE CG1   HG13   sing N N 213 
ILE CG2   HG21   sing N N 214 
ILE CG2   HG22   sing N N 215 
ILE CG2   HG23   sing N N 216 
ILE CD1   HD11   sing N N 217 
ILE CD1   HD12   sing N N 218 
ILE CD1   HD13   sing N N 219 
ILE OXT   HXT    sing N N 220 
LEU N     CA     sing N N 221 
LEU N     H      sing N N 222 
LEU N     H2     sing N N 223 
LEU CA    C      sing N N 224 
LEU CA    CB     sing N N 225 
LEU CA    HA     sing N N 226 
LEU C     O      doub N N 227 
LEU C     OXT    sing N N 228 
LEU CB    CG     sing N N 229 
LEU CB    HB2    sing N N 230 
LEU CB    HB3    sing N N 231 
LEU CG    CD1    sing N N 232 
LEU CG    CD2    sing N N 233 
LEU CG    HG     sing N N 234 
LEU CD1   HD11   sing N N 235 
LEU CD1   HD12   sing N N 236 
LEU CD1   HD13   sing N N 237 
LEU CD2   HD21   sing N N 238 
LEU CD2   HD22   sing N N 239 
LEU CD2   HD23   sing N N 240 
LEU OXT   HXT    sing N N 241 
LYS N     CA     sing N N 242 
LYS N     H      sing N N 243 
LYS N     H2     sing N N 244 
LYS CA    C      sing N N 245 
LYS CA    CB     sing N N 246 
LYS CA    HA     sing N N 247 
LYS C     O      doub N N 248 
LYS C     OXT    sing N N 249 
LYS CB    CG     sing N N 250 
LYS CB    HB2    sing N N 251 
LYS CB    HB3    sing N N 252 
LYS CG    CD     sing N N 253 
LYS CG    HG2    sing N N 254 
LYS CG    HG3    sing N N 255 
LYS CD    CE     sing N N 256 
LYS CD    HD2    sing N N 257 
LYS CD    HD3    sing N N 258 
LYS CE    NZ     sing N N 259 
LYS CE    HE2    sing N N 260 
LYS CE    HE3    sing N N 261 
LYS NZ    HZ1    sing N N 262 
LYS NZ    HZ2    sing N N 263 
LYS NZ    HZ3    sing N N 264 
LYS OXT   HXT    sing N N 265 
MET N     CA     sing N N 266 
MET N     H      sing N N 267 
MET N     H2     sing N N 268 
MET CA    C      sing N N 269 
MET CA    CB     sing N N 270 
MET CA    HA     sing N N 271 
MET C     O      doub N N 272 
MET C     OXT    sing N N 273 
MET CB    CG     sing N N 274 
MET CB    HB2    sing N N 275 
MET CB    HB3    sing N N 276 
MET CG    SD     sing N N 277 
MET CG    HG2    sing N N 278 
MET CG    HG3    sing N N 279 
MET SD    CE     sing N N 280 
MET CE    HE1    sing N N 281 
MET CE    HE2    sing N N 282 
MET CE    HE3    sing N N 283 
MET OXT   HXT    sing N N 284 
PHE N     CA     sing N N 285 
PHE N     H      sing N N 286 
PHE N     H2     sing N N 287 
PHE CA    C      sing N N 288 
PHE CA    CB     sing N N 289 
PHE CA    HA     sing N N 290 
PHE C     O      doub N N 291 
PHE C     OXT    sing N N 292 
PHE CB    CG     sing N N 293 
PHE CB    HB2    sing N N 294 
PHE CB    HB3    sing N N 295 
PHE CG    CD1    doub Y N 296 
PHE CG    CD2    sing Y N 297 
PHE CD1   CE1    sing Y N 298 
PHE CD1   HD1    sing N N 299 
PHE CD2   CE2    doub Y N 300 
PHE CD2   HD2    sing N N 301 
PHE CE1   CZ     doub Y N 302 
PHE CE1   HE1    sing N N 303 
PHE CE2   CZ     sing Y N 304 
PHE CE2   HE2    sing N N 305 
PHE CZ    HZ     sing N N 306 
PHE OXT   HXT    sing N N 307 
PRO N     CA     sing N N 308 
PRO N     CD     sing N N 309 
PRO N     H      sing N N 310 
PRO CA    C      sing N N 311 
PRO CA    CB     sing N N 312 
PRO CA    HA     sing N N 313 
PRO C     O      doub N N 314 
PRO C     OXT    sing N N 315 
PRO CB    CG     sing N N 316 
PRO CB    HB2    sing N N 317 
PRO CB    HB3    sing N N 318 
PRO CG    CD     sing N N 319 
PRO CG    HG2    sing N N 320 
PRO CG    HG3    sing N N 321 
PRO CD    HD2    sing N N 322 
PRO CD    HD3    sing N N 323 
PRO OXT   HXT    sing N N 324 
SER N     CA     sing N N 325 
SER N     H      sing N N 326 
SER N     H2     sing N N 327 
SER CA    C      sing N N 328 
SER CA    CB     sing N N 329 
SER CA    HA     sing N N 330 
SER C     O      doub N N 331 
SER C     OXT    sing N N 332 
SER CB    OG     sing N N 333 
SER CB    HB2    sing N N 334 
SER CB    HB3    sing N N 335 
SER OG    HG     sing N N 336 
SER OXT   HXT    sing N N 337 
THR N     CA     sing N N 338 
THR N     H      sing N N 339 
THR N     H2     sing N N 340 
THR CA    C      sing N N 341 
THR CA    CB     sing N N 342 
THR CA    HA     sing N N 343 
THR C     O      doub N N 344 
THR C     OXT    sing N N 345 
THR CB    OG1    sing N N 346 
THR CB    CG2    sing N N 347 
THR CB    HB     sing N N 348 
THR OG1   HG1    sing N N 349 
THR CG2   HG21   sing N N 350 
THR CG2   HG22   sing N N 351 
THR CG2   HG23   sing N N 352 
THR OXT   HXT    sing N N 353 
TRP N     CA     sing N N 354 
TRP N     H      sing N N 355 
TRP N     H2     sing N N 356 
TRP CA    C      sing N N 357 
TRP CA    CB     sing N N 358 
TRP CA    HA     sing N N 359 
TRP C     O      doub N N 360 
TRP C     OXT    sing N N 361 
TRP CB    CG     sing N N 362 
TRP CB    HB2    sing N N 363 
TRP CB    HB3    sing N N 364 
TRP CG    CD1    doub Y N 365 
TRP CG    CD2    sing Y N 366 
TRP CD1   NE1    sing Y N 367 
TRP CD1   HD1    sing N N 368 
TRP CD2   CE2    doub Y N 369 
TRP CD2   CE3    sing Y N 370 
TRP NE1   CE2    sing Y N 371 
TRP NE1   HE1    sing N N 372 
TRP CE2   CZ2    sing Y N 373 
TRP CE3   CZ3    doub Y N 374 
TRP CE3   HE3    sing N N 375 
TRP CZ2   CH2    doub Y N 376 
TRP CZ2   HZ2    sing N N 377 
TRP CZ3   CH2    sing Y N 378 
TRP CZ3   HZ3    sing N N 379 
TRP CH2   HH2    sing N N 380 
TRP OXT   HXT    sing N N 381 
TYR N     CA     sing N N 382 
TYR N     H      sing N N 383 
TYR N     H2     sing N N 384 
TYR CA    C      sing N N 385 
TYR CA    CB     sing N N 386 
TYR CA    HA     sing N N 387 
TYR C     O      doub N N 388 
TYR C     OXT    sing N N 389 
TYR CB    CG     sing N N 390 
TYR CB    HB2    sing N N 391 
TYR CB    HB3    sing N N 392 
TYR CG    CD1    doub Y N 393 
TYR CG    CD2    sing Y N 394 
TYR CD1   CE1    sing Y N 395 
TYR CD1   HD1    sing N N 396 
TYR CD2   CE2    doub Y N 397 
TYR CD2   HD2    sing N N 398 
TYR CE1   CZ     doub Y N 399 
TYR CE1   HE1    sing N N 400 
TYR CE2   CZ     sing Y N 401 
TYR CE2   HE2    sing N N 402 
TYR CZ    OH     sing N N 403 
TYR OH    HH     sing N N 404 
TYR OXT   HXT    sing N N 405 
VAL N     CA     sing N N 406 
VAL N     H      sing N N 407 
VAL N     H2     sing N N 408 
VAL CA    C      sing N N 409 
VAL CA    CB     sing N N 410 
VAL CA    HA     sing N N 411 
VAL C     O      doub N N 412 
VAL C     OXT    sing N N 413 
VAL CB    CG1    sing N N 414 
VAL CB    CG2    sing N N 415 
VAL CB    HB     sing N N 416 
VAL CG1   HG11   sing N N 417 
VAL CG1   HG12   sing N N 418 
VAL CG1   HG13   sing N N 419 
VAL CG2   HG21   sing N N 420 
VAL CG2   HG22   sing N N 421 
VAL CG2   HG23   sing N N 422 
VAL OXT   HXT    sing N N 423 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-02 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9F6V 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              'cryoEM structure of Asgard tubulin heterodimer AtubA/B2 with GTP' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          2951803 
_em_entity_assembly_naturalsource.organism             'Candidatus Lokiarchaeum ossiferum' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'European Research Council (ERC)' 
_pdbx_audit_support.country                'European Union' 
_pdbx_audit_support.grant_number           101000232 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9F6V 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . ALA A 1 2   ? 126.092 111.020 130.216 1.00 81.49  ? 2   ALA A N     1 
ATOM   2    C CA    . ALA A 1 2   ? 125.341 112.236 130.471 1.00 81.49  ? 2   ALA A CA    1 
ATOM   3    C C     . ALA A 1 2   ? 123.953 112.154 129.863 1.00 81.49  ? 2   ALA A C     1 
ATOM   4    O O     . ALA A 1 2   ? 123.764 111.445 128.885 1.00 81.49  ? 2   ALA A O     1 
ATOM   5    C CB    . ALA A 1 2   ? 126.102 113.463 129.922 1.00 111.12 ? 2   ALA A CB    1 
ATOM   6    N N     . GLY A 1 3   ? 122.998 112.926 130.400 1.00 84.04  ? 3   GLY A N     1 
ATOM   7    C CA    . GLY A 1 3   ? 121.609 112.908 129.950 1.00 84.04  ? 3   GLY A CA    1 
ATOM   8    C C     . GLY A 1 3   ? 120.834 111.792 130.597 1.00 84.04  ? 3   GLY A C     1 
ATOM   9    O O     . GLY A 1 3   ? 119.933 111.207 129.995 1.00 84.04  ? 3   GLY A O     1 
ATOM   10   N N     . GLU A 1 4   ? 121.223 111.458 131.808 1.00 83.12  ? 4   GLU A N     1 
ATOM   11   C CA    . GLU A 1 4   ? 120.730 110.361 132.600 1.00 83.12  ? 4   GLU A CA    1 
ATOM   12   C C     . GLU A 1 4   ? 119.462 110.725 133.353 1.00 83.12  ? 4   GLU A C     1 
ATOM   13   O O     . GLU A 1 4   ? 119.227 111.889 133.655 1.00 83.12  ? 4   GLU A O     1 
ATOM   14   C CB    . GLU A 1 4   ? 121.849 109.976 133.523 1.00 111.64 ? 4   GLU A CB    1 
ATOM   15   C CG    . GLU A 1 4   ? 123.039 109.401 132.741 1.00 111.64 ? 4   GLU A CG    1 
ATOM   16   C CD    . GLU A 1 4   ? 124.276 109.139 133.578 1.00 111.64 ? 4   GLU A CD    1 
ATOM   17   O OE1   . GLU A 1 4   ? 124.902 110.097 134.044 1.00 111.64 ? 4   GLU A OE1   1 
ATOM   18   O OE2   . GLU A 1 4   ? 124.624 107.973 133.777 1.00 111.64 ? 4   GLU A OE2   1 
ATOM   19   N N     . ILE A 1 5   ? 118.609 109.755 133.643 1.00 81.43  ? 5   ILE A N     1 
ATOM   20   C CA    . ILE A 1 5   ? 117.312 110.067 134.244 1.00 81.43  ? 5   ILE A CA    1 
ATOM   21   C C     . ILE A 1 5   ? 117.085 109.390 135.585 1.00 81.43  ? 5   ILE A C     1 
ATOM   22   O O     . ILE A 1 5   ? 117.248 108.181 135.714 1.00 81.43  ? 5   ILE A O     1 
ATOM   23   C CB    . ILE A 1 5   ? 116.183 109.683 133.308 1.00 120.49 ? 5   ILE A CB    1 
ATOM   24   C CG1   . ILE A 1 5   ? 116.309 110.500 132.050 1.00 120.49 ? 5   ILE A CG1   1 
ATOM   25   C CG2   . ILE A 1 5   ? 114.890 109.924 133.975 1.00 120.49 ? 5   ILE A CG2   1 
ATOM   26   C CD1   . ILE A 1 5   ? 115.416 110.063 130.917 1.00 120.49 ? 5   ILE A CD1   1 
ATOM   27   N N     . VAL A 1 6   ? 116.675 110.157 136.577 1.00 80.97  ? 6   VAL A N     1 
ATOM   28   C CA    . VAL A 1 6   ? 116.320 109.607 137.879 1.00 80.97  ? 6   VAL A CA    1 
ATOM   29   C C     . VAL A 1 6   ? 114.802 109.505 137.973 1.00 80.97  ? 6   VAL A C     1 
ATOM   30   O O     . VAL A 1 6   ? 114.108 110.484 137.721 1.00 80.97  ? 6   VAL A O     1 
ATOM   31   C CB    . VAL A 1 6   ? 116.901 110.472 139.001 1.00 117.74 ? 6   VAL A CB    1 
ATOM   32   C CG1   . VAL A 1 6   ? 116.502 109.925 140.322 1.00 117.74 ? 6   VAL A CG1   1 
ATOM   33   C CG2   . VAL A 1 6   ? 118.381 110.495 138.898 1.00 117.74 ? 6   VAL A CG2   1 
ATOM   34   N N     . CYS A 1 7   ? 114.268 108.343 138.335 1.00 90.47  ? 7   CYS A N     1 
ATOM   35   C CA    . CYS A 1 7   ? 112.821 108.109 138.392 1.00 90.47  ? 7   CYS A CA    1 
ATOM   36   C C     . CYS A 1 7   ? 112.254 108.011 139.806 1.00 90.47  ? 7   CYS A C     1 
ATOM   37   O O     . CYS A 1 7   ? 112.695 107.176 140.591 1.00 90.47  ? 7   CYS A O     1 
ATOM   38   C CB    . CYS A 1 7   ? 112.477 106.830 137.679 1.00 121.86 ? 7   CYS A CB    1 
ATOM   39   S SG    . CYS A 1 7   ? 112.936 106.889 135.977 1.00 121.86 ? 7   CYS A SG    1 
ATOM   40   N N     . ILE A 1 8   ? 111.245 108.814 140.128 1.00 93.51  ? 8   ILE A N     1 
ATOM   41   C CA    . ILE A 1 8   ? 110.688 108.854 141.477 1.00 93.51  ? 8   ILE A CA    1 
ATOM   42   C C     . ILE A 1 8   ? 109.260 108.346 141.458 1.00 93.51  ? 8   ILE A C     1 
ATOM   43   O O     . ILE A 1 8   ? 108.408 108.892 140.761 1.00 93.51  ? 8   ILE A O     1 
ATOM   44   C CB    . ILE A 1 8   ? 110.777 110.256 142.053 1.00 138.36 ? 8   ILE A CB    1 
ATOM   45   C CG1   . ILE A 1 8   ? 112.224 110.699 142.000 1.00 138.36 ? 8   ILE A CG1   1 
ATOM   46   C CG2   . ILE A 1 8   ? 110.292 110.245 143.488 1.00 138.36 ? 8   ILE A CG2   1 
ATOM   47   C CD1   . ILE A 1 8   ? 112.444 112.101 142.302 1.00 138.36 ? 8   ILE A CD1   1 
ATOM   48   N N     . GLN A 1 9   ? 108.998 107.309 142.202 1.00 101.25 ? 9   GLN A N     1 
ATOM   49   C CA    . GLN A 1 9   ? 107.708 106.654 142.225 1.00 101.25 ? 9   GLN A CA    1 
ATOM   50   C C     . GLN A 1 9   ? 106.997 106.973 143.524 1.00 101.25 ? 9   GLN A C     1 
ATOM   51   O O     . GLN A 1 9   ? 107.496 106.612 144.581 1.00 101.25 ? 9   GLN A O     1 
ATOM   52   C CB    . GLN A 1 9   ? 107.924 105.169 142.122 1.00 141.44 ? 9   GLN A CB    1 
ATOM   53   C CG    . GLN A 1 9   ? 108.725 104.788 140.973 1.00 141.44 ? 9   GLN A CG    1 
ATOM   54   C CD    . GLN A 1 9   ? 109.073 103.326 140.953 1.00 141.44 ? 9   GLN A CD    1 
ATOM   55   O OE1   . GLN A 1 9   ? 109.868 102.892 140.116 1.00 141.44 ? 9   GLN A OE1   1 
ATOM   56   N NE2   . GLN A 1 9   ? 108.477 102.543 141.856 1.00 141.44 ? 9   GLN A NE2   1 
ATOM   57   N N     . VAL A 1 10  ? 105.849 107.635 143.496 1.00 103.44 ? 10  VAL A N     1 
ATOM   58   C CA    . VAL A 1 10  ? 105.239 108.036 144.753 1.00 103.44 ? 10  VAL A CA    1 
ATOM   59   C C     . VAL A 1 10  ? 103.827 107.531 144.915 1.00 103.44 ? 10  VAL A C     1 
ATOM   60   O O     . VAL A 1 10  ? 102.949 107.895 144.136 1.00 103.44 ? 10  VAL A O     1 
ATOM   61   C CB    . VAL A 1 10  ? 105.227 109.541 144.883 1.00 150.41 ? 10  VAL A CB    1 
ATOM   62   C CG1   . VAL A 1 10  ? 104.640 109.917 146.219 1.00 150.41 ? 10  VAL A CG1   1 
ATOM   63   C CG2   . VAL A 1 10  ? 106.613 110.093 144.704 1.00 150.41 ? 10  VAL A CG2   1 
ATOM   64   N N     . GLY A 1 11  ? 103.582 106.785 145.971 1.00 108.39 ? 11  GLY A N     1 
ATOM   65   C CA    . GLY A 1 11  ? 102.265 106.279 146.304 1.00 108.39 ? 11  GLY A CA    1 
ATOM   66   C C     . GLY A 1 11  ? 102.042 104.956 145.640 1.00 108.39 ? 11  GLY A C     1 
ATOM   67   O O     . GLY A 1 11  ? 102.842 104.542 144.821 1.00 108.39 ? 11  GLY A O     1 
ATOM   68   N N     . GLN A 1 12  ? 100.912 104.334 145.961 1.00 109.09 ? 12  GLN A N     1 
ATOM   69   C CA    . GLN A 1 12  ? 100.544 103.035 145.402 1.00 109.09 ? 12  GLN A CA    1 
ATOM   70   C C     . GLN A 1 12  ? 100.458 103.066 143.931 1.00 109.09 ? 12  GLN A C     1 
ATOM   71   O O     . GLN A 1 12  ? 101.038 102.236 143.247 1.00 109.09 ? 12  GLN A O     1 
ATOM   72   C CB    . GLN A 1 12  ? 99.188  102.600 145.879 1.00 152.39 ? 12  GLN A CB    1 
ATOM   73   C CG    . GLN A 1 12  ? 98.678  101.316 145.262 1.00 152.39 ? 12  GLN A CG    1 
ATOM   74   C CD    . GLN A 1 12  ? 97.209  101.095 145.550 1.00 152.39 ? 12  GLN A CD    1 
ATOM   75   O OE1   . GLN A 1 12  ? 96.650  100.046 145.232 1.00 152.39 ? 12  GLN A OE1   1 
ATOM   76   N NE2   . GLN A 1 12  ? 96.573  102.087 146.157 1.00 152.39 ? 12  GLN A NE2   1 
ATOM   77   N N     . ALA A 1 13  ? 99.715  104.001 143.420 1.00 106.96 ? 13  ALA A N     1 
ATOM   78   C CA    . ALA A 1 13  ? 99.548  104.019 141.985 1.00 106.96 ? 13  ALA A CA    1 
ATOM   79   C C     . ALA A 1 13  ? 100.898 104.170 141.347 1.00 106.96 ? 13  ALA A C     1 
ATOM   80   O O     . ALA A 1 13  ? 101.228 103.498 140.366 1.00 106.96 ? 13  ALA A O     1 
ATOM   81   C CB    . ALA A 1 13  ? 98.638  105.151 141.550 1.00 145.85 ? 13  ALA A CB    1 
ATOM   82   N N     . GLY A 1 14  ? 101.712 105.010 141.947 1.00 106.31 ? 14  GLY A N     1 
ATOM   83   C CA    . GLY A 1 14  ? 103.025 105.272 141.421 1.00 106.31 ? 14  GLY A CA    1 
ATOM   84   C C     . GLY A 1 14  ? 103.865 104.025 141.376 1.00 106.31 ? 14  GLY A C     1 
ATOM   85   O O     . GLY A 1 14  ? 104.478 103.716 140.352 1.00 106.31 ? 14  GLY A O     1 
ATOM   86   N N     . ASN A 1 15  ? 103.880 103.277 142.466 1.00 105.92 ? 15  ASN A N     1 
ATOM   87   C CA    . ASN A 1 15  ? 104.743 102.133 142.535 1.00 105.92 ? 15  ASN A CA    1 
ATOM   88   C C     . ASN A 1 15  ? 104.255 100.997 141.670 1.00 105.92 ? 15  ASN A C     1 
ATOM   89   O O     . ASN A 1 15  ? 105.083 100.277 141.108 1.00 105.92 ? 15  ASN A O     1 
ATOM   90   C CB    . ASN A 1 15  ? 104.902 101.726 143.958 1.00 143.49 ? 15  ASN A CB    1 
ATOM   91   C CG    . ASN A 1 15  ? 105.696 102.702 144.676 1.00 143.49 ? 15  ASN A CG    1 
ATOM   92   O OD1   . ASN A 1 15  ? 106.639 103.261 144.134 1.00 143.49 ? 15  ASN A OD1   1 
ATOM   93   N ND2   . ASN A 1 15  ? 105.330 102.975 145.903 1.00 143.49 ? 15  ASN A ND2   1 
ATOM   94   N N     . GLN A 1 16  ? 102.948 100.838 141.485 1.00 102.97 ? 16  GLN A N     1 
ATOM   95   C CA    . GLN A 1 16  ? 102.503 99.737  140.645 1.00 102.97 ? 16  GLN A CA    1 
ATOM   96   C C     . GLN A 1 16  ? 102.677 100.043 139.180 1.00 102.97 ? 16  GLN A C     1 
ATOM   97   O O     . GLN A 1 16  ? 103.084 99.173  138.399 1.00 102.97 ? 16  GLN A O     1 
ATOM   98   C CB    . GLN A 1 16  ? 101.061 99.385  140.927 1.00 143.84 ? 16  GLN A CB    1 
ATOM   99   C CG    . GLN A 1 16  ? 100.837 98.811  142.288 1.00 143.84 ? 16  GLN A CG    1 
ATOM   100  C CD    . GLN A 1 16  ? 101.603 97.548  142.518 1.00 143.84 ? 16  GLN A CD    1 
ATOM   101  O OE1   . GLN A 1 16  ? 101.640 96.667  141.661 1.00 143.84 ? 16  GLN A OE1   1 
ATOM   102  N NE2   . GLN A 1 16  ? 102.235 97.447  143.672 1.00 143.84 ? 16  GLN A NE2   1 
ATOM   103  N N     . ILE A 1 17  ? 102.414 101.269 138.781 1.00 99.30  ? 17  ILE A N     1 
ATOM   104  C CA    . ILE A 1 17  ? 102.586 101.597 137.390 1.00 99.30  ? 17  ILE A CA    1 
ATOM   105  C C     . ILE A 1 17  ? 104.026 101.525 137.043 1.00 99.30  ? 17  ILE A C     1 
ATOM   106  O O     . ILE A 1 17  ? 104.416 100.970 136.018 1.00 99.30  ? 17  ILE A O     1 
ATOM   107  C CB    . ILE A 1 17  ? 102.058 102.990 137.090 1.00 146.93 ? 17  ILE A CB    1 
ATOM   108  C CG1   . ILE A 1 17  ? 100.554 103.000 137.270 1.00 146.93 ? 17  ILE A CG1   1 
ATOM   109  C CG2   . ILE A 1 17  ? 102.488 103.385 135.730 1.00 146.93 ? 17  ILE A CG2   1 
ATOM   110  C CD1   . ILE A 1 17  ? 99.937  104.378 137.353 1.00 146.93 ? 17  ILE A CD1   1 
ATOM   111  N N     . ALA A 1 18  ? 104.832 102.128 137.869 1.00 98.85  ? 18  ALA A N     1 
ATOM   112  C CA    . ALA A 1 18  ? 106.230 102.144 137.602 1.00 98.85  ? 18  ALA A CA    1 
ATOM   113  C C     . ALA A 1 18  ? 106.793 100.756 137.657 1.00 98.85  ? 18  ALA A C     1 
ATOM   114  O O     . ALA A 1 18  ? 107.683 100.430 136.880 1.00 98.85  ? 18  ALA A O     1 
ATOM   115  C CB    . ALA A 1 18  ? 106.925 103.049 138.584 1.00 134.79 ? 18  ALA A CB    1 
ATOM   116  N N     . GLY A 1 19  ? 106.312 99.920  138.544 1.00 99.63  ? 19  GLY A N     1 
ATOM   117  C CA    . GLY A 1 19  ? 106.851 98.593  138.579 1.00 99.63  ? 19  GLY A CA    1 
ATOM   118  C C     . GLY A 1 19  ? 106.635 97.902  137.262 1.00 99.63  ? 19  GLY A C     1 
ATOM   119  O O     . GLY A 1 19  ? 107.545 97.255  136.733 1.00 99.63  ? 19  GLY A O     1 
ATOM   120  N N     . ALA A 1 20  ? 105.441 98.055  136.695 1.00 96.81  ? 20  ALA A N     1 
ATOM   121  C CA    . ALA A 1 20  ? 105.180 97.463  135.394 1.00 96.81  ? 20  ALA A CA    1 
ATOM   122  C C     . ALA A 1 20  ? 106.098 98.046  134.325 1.00 96.81  ? 20  ALA A C     1 
ATOM   123  O O     . ALA A 1 20  ? 106.606 97.318  133.455 1.00 96.81  ? 20  ALA A O     1 
ATOM   124  C CB    . ALA A 1 20  ? 103.724 97.669  135.032 1.00 132.01 ? 20  ALA A CB    1 
ATOM   125  N N     . PHE A 1 21  ? 106.342 99.351  134.401 1.00 91.78  ? 21  PHE A N     1 
ATOM   126  C CA    . PHE A 1 21  ? 107.268 100.008 133.496 1.00 91.78  ? 21  PHE A CA    1 
ATOM   127  C C     . PHE A 1 21  ? 108.620 99.386  133.581 1.00 91.78  ? 21  PHE A C     1 
ATOM   128  O O     . PHE A 1 21  ? 109.239 99.087  132.557 1.00 91.78  ? 21  PHE A O     1 
ATOM   129  C CB    . PHE A 1 21  ? 107.392 101.484 133.818 1.00 128.02 ? 21  PHE A CB    1 
ATOM   130  C CG    . PHE A 1 21  ? 108.557 102.142 133.193 1.00 128.02 ? 21  PHE A CG    1 
ATOM   131  C CD1   . PHE A 1 21  ? 108.560 102.519 131.892 1.00 128.02 ? 21  PHE A CD1   1 
ATOM   132  C CD2   . PHE A 1 21  ? 109.644 102.402 133.937 1.00 128.02 ? 21  PHE A CD2   1 
ATOM   133  C CE1   . PHE A 1 21  ? 109.655 103.125 131.355 1.00 128.02 ? 21  PHE A CE1   1 
ATOM   134  C CE2   . PHE A 1 21  ? 110.741 102.998 133.409 1.00 128.02 ? 21  PHE A CE2   1 
ATOM   135  C CZ    . PHE A 1 21  ? 110.745 103.362 132.121 1.00 128.02 ? 21  PHE A CZ    1 
ATOM   136  N N     . TRP A 1 22  ? 109.121 99.231  134.787 1.00 93.06  ? 22  TRP A N     1 
ATOM   137  C CA    . TRP A 1 22  ? 110.470 98.740  134.941 1.00 93.06  ? 22  TRP A CA    1 
ATOM   138  C C     . TRP A 1 22  ? 110.585 97.331  134.407 1.00 93.06  ? 22  TRP A C     1 
ATOM   139  O O     . TRP A 1 22  ? 111.606 96.985  133.811 1.00 93.06  ? 22  TRP A O     1 
ATOM   140  C CB    . TRP A 1 22  ? 110.937 98.833  136.375 1.00 128.79 ? 22  TRP A CB    1 
ATOM   141  C CG    . TRP A 1 22  ? 111.335 100.169 136.736 1.00 128.79 ? 22  TRP A CG    1 
ATOM   142  C CD1   . TRP A 1 22  ? 110.704 100.968 137.589 1.00 128.79 ? 22  TRP A CD1   1 
ATOM   143  C CD2   . TRP A 1 22  ? 112.447 100.883 136.271 1.00 128.79 ? 22  TRP A CD2   1 
ATOM   144  N NE1   . TRP A 1 22  ? 111.347 102.135 137.691 1.00 128.79 ? 22  TRP A NE1   1 
ATOM   145  C CE2   . TRP A 1 22  ? 112.426 102.102 136.865 1.00 128.79 ? 22  TRP A CE2   1 
ATOM   146  C CE3   . TRP A 1 22  ? 113.443 100.609 135.379 1.00 128.79 ? 22  TRP A CE3   1 
ATOM   147  C CZ2   . TRP A 1 22  ? 113.363 103.040 136.629 1.00 128.79 ? 22  TRP A CZ2   1 
ATOM   148  C CZ3   . TRP A 1 22  ? 114.376 101.542 135.136 1.00 128.79 ? 22  TRP A CZ3   1 
ATOM   149  C CH2   . TRP A 1 22  ? 114.340 102.741 135.757 1.00 128.79 ? 22  TRP A CH2   1 
ATOM   150  N N     . GLN A 1 23  ? 109.546 96.518  134.540 1.00 92.12  ? 23  GLN A N     1 
ATOM   151  C CA    . GLN A 1 23  ? 109.674 95.192  133.955 1.00 92.12  ? 23  GLN A CA    1 
ATOM   152  C C     . GLN A 1 23  ? 109.753 95.269  132.438 1.00 92.12  ? 23  GLN A C     1 
ATOM   153  O O     . GLN A 1 23  ? 110.576 94.573  131.816 1.00 92.12  ? 23  GLN A O     1 
ATOM   154  C CB    . GLN A 1 23  ? 108.539 94.294  134.388 1.00 128.68 ? 23  GLN A CB    1 
ATOM   155  C CG    . GLN A 1 23  ? 108.588 93.902  135.798 1.00 128.68 ? 23  GLN A CG    1 
ATOM   156  C CD    . GLN A 1 23  ? 107.456 93.061  136.147 1.00 128.68 ? 23  GLN A CD    1 
ATOM   157  O OE1   . GLN A 1 23  ? 106.409 93.166  135.534 1.00 128.68 ? 23  GLN A OE1   1 
ATOM   158  N NE2   . GLN A 1 23  ? 107.627 92.200  137.119 1.00 128.68 ? 23  GLN A NE2   1 
ATOM   159  N N     . LYS A 1 24  ? 108.954 96.137  131.817 1.00 88.80  ? 24  LYS A N     1 
ATOM   160  C CA    . LYS A 1 24  ? 109.011 96.185  130.361 1.00 88.80  ? 24  LYS A CA    1 
ATOM   161  C C     . LYS A 1 24  ? 110.337 96.745  129.866 1.00 88.80  ? 24  LYS A C     1 
ATOM   162  O O     . LYS A 1 24  ? 110.899 96.250  128.878 1.00 88.80  ? 24  LYS A O     1 
ATOM   163  C CB    . LYS A 1 24  ? 107.863 96.983  129.775 1.00 133.08 ? 24  LYS A CB    1 
ATOM   164  C CG    . LYS A 1 24  ? 106.538 96.293  129.782 1.00 133.08 ? 24  LYS A CG    1 
ATOM   165  C CD    . LYS A 1 24  ? 105.486 97.167  129.132 1.00 133.08 ? 24  LYS A CD    1 
ATOM   166  C CE    . LYS A 1 24  ? 104.132 96.487  129.051 1.00 133.08 ? 24  LYS A CE    1 
ATOM   167  N NZ    . LYS A 1 24  ? 104.144 95.368  128.100 1.00 133.08 ? 24  LYS A NZ    1 
ATOM   168  N N     . ILE A 1 25  ? 110.855 97.767  130.525 1.00 88.85  ? 25  ILE A N     1 
ATOM   169  C CA    . ILE A 1 25  ? 112.094 98.341  130.058 1.00 88.85  ? 25  ILE A CA    1 
ATOM   170  C C     . ILE A 1 25  ? 113.207 97.347  130.248 1.00 88.85  ? 25  ILE A C     1 
ATOM   171  O O     . ILE A 1 25  ? 114.113 97.266  129.419 1.00 88.85  ? 25  ILE A O     1 
ATOM   172  C CB    . ILE A 1 25  ? 112.366 99.684  130.741 1.00 131.46 ? 25  ILE A CB    1 
ATOM   173  C CG1   . ILE A 1 25  ? 113.499 100.384 130.088 1.00 131.46 ? 25  ILE A CG1   1 
ATOM   174  C CG2   . ILE A 1 25  ? 112.670 99.494  132.114 1.00 131.46 ? 25  ILE A CG2   1 
ATOM   175  C CD1   . ILE A 1 25  ? 113.665 101.835 130.504 1.00 131.46 ? 25  ILE A CD1   1 
ATOM   176  N N     . CYS A 1 26  ? 113.156 96.544  131.300 1.00 94.58  ? 26  CYS A N     1 
ATOM   177  C CA    . CYS A 1 26  ? 114.206 95.558  131.431 1.00 94.58  ? 26  CYS A CA    1 
ATOM   178  C C     . CYS A 1 26  ? 114.169 94.599  130.267 1.00 94.58  ? 26  CYS A C     1 
ATOM   179  O O     . CYS A 1 26  ? 115.212 94.236  129.713 1.00 94.58  ? 26  CYS A O     1 
ATOM   180  C CB    . CYS A 1 26  ? 114.073 94.797  132.733 1.00 127.39 ? 26  CYS A CB    1 
ATOM   181  S SG    . CYS A 1 26  ? 114.418 95.769  134.188 1.00 127.39 ? 26  CYS A SG    1 
ATOM   182  N N     . ALA A 1 27  ? 112.986 94.194  129.861 1.00 88.77  ? 27  ALA A N     1 
ATOM   183  C CA    . ALA A 1 27  ? 112.925 93.246  128.764 1.00 88.77  ? 27  ALA A CA    1 
ATOM   184  C C     . ALA A 1 27  ? 113.502 93.818  127.505 1.00 88.77  ? 27  ALA A C     1 
ATOM   185  O O     . ALA A 1 27  ? 114.277 93.163  126.813 1.00 88.77  ? 27  ALA A O     1 
ATOM   186  C CB    . ALA A 1 27  ? 111.494 92.836  128.509 1.00 121.05 ? 27  ALA A CB    1 
ATOM   187  N N     . GLU A 1 28  ? 113.210 95.067  127.228 1.00 89.96  ? 28  GLU A N     1 
ATOM   188  C CA    . GLU A 1 28  ? 113.708 95.627  125.985 1.00 89.96  ? 28  GLU A CA    1 
ATOM   189  C C     . GLU A 1 28  ? 115.205 95.744  125.959 1.00 89.96  ? 28  GLU A C     1 
ATOM   190  O O     . GLU A 1 28  ? 115.806 95.624  124.898 1.00 89.96  ? 28  GLU A O     1 
ATOM   191  C CB    . GLU A 1 28  ? 113.122 96.995  125.713 1.00 120.83 ? 28  GLU A CB    1 
ATOM   192  C CG    . GLU A 1 28  ? 111.685 96.975  125.369 1.00 120.83 ? 28  GLU A CG    1 
ATOM   193  C CD    . GLU A 1 28  ? 111.247 98.261  124.820 1.00 120.83 ? 28  GLU A CD    1 
ATOM   194  O OE1   . GLU A 1 28  ? 112.068 99.162  124.733 1.00 120.83 ? 28  GLU A OE1   1 
ATOM   195  O OE2   . GLU A 1 28  ? 110.080 98.393  124.495 1.00 120.83 ? 28  GLU A OE2   1 
ATOM   196  N N     . HIS A 1 29  ? 115.825 95.990  127.075 1.00 85.52  ? 29  HIS A N     1 
ATOM   197  C CA    . HIS A 1 29  ? 117.242 96.197  127.058 1.00 85.52  ? 29  HIS A CA    1 
ATOM   198  C C     . HIS A 1 29  ? 118.023 94.967  127.350 1.00 85.52  ? 29  HIS A C     1 
ATOM   199  O O     . HIS A 1 29  ? 119.225 95.064  127.551 1.00 85.52  ? 29  HIS A O     1 
ATOM   200  C CB    . HIS A 1 29  ? 117.616 97.272  128.010 1.00 116.29 ? 29  HIS A CB    1 
ATOM   201  C CG    . HIS A 1 29  ? 117.191 98.562  127.523 1.00 116.29 ? 29  HIS A CG    1 
ATOM   202  N ND1   . HIS A 1 29  ? 117.934 99.279  126.644 1.00 116.29 ? 29  HIS A ND1   1 
ATOM   203  C CD2   . HIS A 1 29  ? 116.063 99.236  127.719 1.00 116.29 ? 29  HIS A CD2   1 
ATOM   204  C CE1   . HIS A 1 29  ? 117.285 100.373 126.334 1.00 116.29 ? 29  HIS A CE1   1 
ATOM   205  N NE2   . HIS A 1 29  ? 116.140 100.366 126.972 1.00 116.29 ? 29  HIS A NE2   1 
ATOM   206  N N     . GLY A 1 30  ? 117.396 93.809  127.368 1.00 88.59  ? 30  GLY A N     1 
ATOM   207  C CA    . GLY A 1 30  ? 118.164 92.602  127.577 1.00 88.59  ? 30  GLY A CA    1 
ATOM   208  C C     . GLY A 1 30  ? 118.626 92.393  128.996 1.00 88.59  ? 30  GLY A C     1 
ATOM   209  O O     . GLY A 1 30  ? 119.712 91.855  129.218 1.00 88.59  ? 30  GLY A O     1 
ATOM   210  N N     . ILE A 1 31  ? 117.853 92.848  129.954 1.00 90.93  ? 31  ILE A N     1 
ATOM   211  C CA    . ILE A 1 31  ? 118.142 92.738  131.365 1.00 90.93  ? 31  ILE A CA    1 
ATOM   212  C C     . ILE A 1 31  ? 117.103 91.830  131.991 1.00 90.93  ? 31  ILE A C     1 
ATOM   213  O O     . ILE A 1 31  ? 115.915 92.026  131.775 1.00 90.93  ? 31  ILE A O     1 
ATOM   214  C CB    . ILE A 1 31  ? 118.065 94.115  132.006 1.00 134.54 ? 31  ILE A CB    1 
ATOM   215  C CG1   . ILE A 1 31  ? 119.067 95.011  131.344 1.00 134.54 ? 31  ILE A CG1   1 
ATOM   216  C CG2   . ILE A 1 31  ? 118.248 94.002  133.490 1.00 134.54 ? 31  ILE A CG2   1 
ATOM   217  C CD1   . ILE A 1 31  ? 118.910 96.442  131.669 1.00 134.54 ? 31  ILE A CD1   1 
ATOM   218  N N     . ASP A 1 32  ? 117.520 90.832  132.725 1.00 95.34  ? 32  ASP A N     1 
ATOM   219  C CA    . ASP A 1 32  ? 116.512 89.971  133.331 1.00 95.34  ? 32  ASP A CA    1 
ATOM   220  C C     . ASP A 1 32  ? 116.024 90.624  134.610 1.00 95.34  ? 32  ASP A C     1 
ATOM   221  O O     . ASP A 1 32  ? 116.767 90.670  135.595 1.00 95.34  ? 32  ASP A O     1 
ATOM   222  C CB    . ASP A 1 32  ? 117.065 88.579  133.639 1.00 122.58 ? 32  ASP A CB    1 
ATOM   223  C CG    . ASP A 1 32  ? 116.001 87.633  134.151 1.00 122.58 ? 32  ASP A CG    1 
ATOM   224  O OD1   . ASP A 1 32  ? 114.993 88.099  134.701 1.00 122.58 ? 32  ASP A OD1   1 
ATOM   225  O OD2   . ASP A 1 32  ? 116.167 86.421  134.008 1.00 122.58 ? 32  ASP A OD2   1 
ATOM   226  N N     . PRO A 1 33  ? 114.759 91.038  134.655 1.00 94.26  ? 33  PRO A N     1 
ATOM   227  C CA    . PRO A 1 33  ? 114.227 91.822  135.767 1.00 94.26  ? 33  PRO A CA    1 
ATOM   228  C C     . PRO A 1 33  ? 114.216 91.101  137.064 1.00 94.26  ? 33  PRO A C     1 
ATOM   229  O O     . PRO A 1 33  ? 114.069 91.726  138.117 1.00 94.26  ? 33  PRO A O     1 
ATOM   230  C CB    . PRO A 1 33  ? 112.801 92.114  135.305 1.00 294.00 ? 33  PRO A CB    1 
ATOM   231  C CG    . PRO A 1 33  ? 112.506 91.020  134.369 1.00 294.00 ? 33  PRO A CG    1 
ATOM   232  C CD    . PRO A 1 33  ? 113.753 90.736  133.661 1.00 294.00 ? 33  PRO A CD    1 
ATOM   233  N N     . VAL A 1 34  ? 114.327 89.796  137.047 1.00 94.96  ? 34  VAL A N     1 
ATOM   234  C CA    . VAL A 1 34  ? 114.258 89.110  138.310 1.00 94.96  ? 34  VAL A CA    1 
ATOM   235  C C     . VAL A 1 34  ? 115.464 89.431  139.147 1.00 94.96  ? 34  VAL A C     1 
ATOM   236  O O     . VAL A 1 34  ? 115.394 89.356  140.370 1.00 94.96  ? 34  VAL A O     1 
ATOM   237  C CB    . VAL A 1 34  ? 114.122 87.593  138.115 1.00 138.08 ? 34  VAL A CB    1 
ATOM   238  C CG1   . VAL A 1 34  ? 115.468 86.954  137.740 1.00 138.08 ? 34  VAL A CG1   1 
ATOM   239  C CG2   . VAL A 1 34  ? 113.562 86.963  139.374 1.00 138.08 ? 34  VAL A CG2   1 
ATOM   240  N N     . ASN A 1 35  ? 116.605 89.700  138.539 1.00 97.02  ? 35  ASN A N     1 
ATOM   241  C CA    . ASN A 1 35  ? 117.782 89.972  139.347 1.00 97.02  ? 35  ASN A CA    1 
ATOM   242  C C     . ASN A 1 35  ? 118.725 91.020  138.785 1.00 97.02  ? 35  ASN A C     1 
ATOM   243  O O     . ASN A 1 35  ? 119.757 91.289  139.401 1.00 97.02  ? 35  ASN A O     1 
ATOM   244  C CB    . ASN A 1 35  ? 118.537 88.688  139.590 1.00 131.43 ? 35  ASN A CB    1 
ATOM   245  C CG    . ASN A 1 35  ? 118.955 88.031  138.330 1.00 131.43 ? 35  ASN A CG    1 
ATOM   246  O OD1   . ASN A 1 35  ? 119.068 88.655  137.278 1.00 131.43 ? 35  ASN A OD1   1 
ATOM   247  N ND2   . ASN A 1 35  ? 119.197 86.740  138.419 1.00 131.43 ? 35  ASN A ND2   1 
ATOM   248  N N     . GLY A 1 36  ? 118.397 91.634  137.664 1.00 93.51  ? 36  GLY A N     1 
ATOM   249  C CA    . GLY A 1 36  ? 119.230 92.654  137.087 1.00 93.51  ? 36  GLY A CA    1 
ATOM   250  C C     . GLY A 1 36  ? 120.373 92.129  136.257 1.00 93.51  ? 36  GLY A C     1 
ATOM   251  O O     . GLY A 1 36  ? 121.173 92.923  135.748 1.00 93.51  ? 36  GLY A O     1 
ATOM   252  N N     . LYS A 1 37  ? 120.496 90.825  136.098 1.00 93.40  ? 37  LYS A N     1 
ATOM   253  C CA    . LYS A 1 37  ? 121.623 90.322  135.341 1.00 93.40  ? 37  LYS A CA    1 
ATOM   254  C C     . LYS A 1 37  ? 121.467 90.573  133.867 1.00 93.40  ? 37  LYS A C     1 
ATOM   255  O O     . LYS A 1 37  ? 120.400 90.396  133.287 1.00 93.40  ? 37  LYS A O     1 
ATOM   256  C CB    . LYS A 1 37  ? 121.823 88.846  135.552 1.00 139.97 ? 37  LYS A CB    1 
ATOM   257  C CG    . LYS A 1 37  ? 122.272 88.451  136.925 1.00 139.97 ? 37  LYS A CG    1 
ATOM   258  C CD    . LYS A 1 37  ? 123.729 88.839  137.153 1.00 139.97 ? 37  LYS A CD    1 
ATOM   259  C CE    . LYS A 1 37  ? 124.301 88.243  138.438 1.00 139.97 ? 37  LYS A CE    1 
ATOM   260  N NZ    . LYS A 1 37  ? 125.755 88.583  138.612 1.00 139.97 ? 37  LYS A NZ    1 
ATOM   261  N N     . ALA A 1 38  ? 122.562 90.945  133.255 1.00 91.84  ? 38  ALA A N     1 
ATOM   262  C CA    . ALA A 1 38  ? 122.586 91.110  131.821 1.00 91.84  ? 38  ALA A CA    1 
ATOM   263  C C     . ALA A 1 38  ? 122.272 89.817  131.127 1.00 91.84  ? 38  ALA A C     1 
ATOM   264  O O     . ALA A 1 38  ? 122.783 88.772  131.502 1.00 91.84  ? 38  ALA A O     1 
ATOM   265  C CB    . ALA A 1 38  ? 123.960 91.548  131.382 1.00 125.24 ? 38  ALA A CB    1 
ATOM   266  N N     . ILE A 1 39  ? 121.485 89.893  130.072 1.00 83.52  ? 39  ILE A N     1 
ATOM   267  C CA    . ILE A 1 39  ? 121.236 88.750  129.212 1.00 83.52  ? 39  ILE A CA    1 
ATOM   268  C C     . ILE A 1 39  ? 122.072 88.969  127.972 1.00 83.52  ? 39  ILE A C     1 
ATOM   269  O O     . ILE A 1 39  ? 122.917 88.151  127.600 1.00 83.52  ? 39  ILE A O     1 
ATOM   270  C CB    . ILE A 1 39  ? 119.762 88.649  128.801 1.00 123.58 ? 39  ILE A CB    1 
ATOM   271  C CG1   . ILE A 1 39  ? 118.880 88.515  130.023 1.00 123.58 ? 39  ILE A CG1   1 
ATOM   272  C CG2   . ILE A 1 39  ? 119.579 87.514  127.853 1.00 123.58 ? 39  ILE A CG2   1 
ATOM   273  C CD1   . ILE A 1 39  ? 117.406 88.726  129.738 1.00 123.58 ? 39  ILE A CD1   1 
ATOM   274  N N     . ASP A 1 40  ? 121.750 90.064  127.290 1.00 81.84  ? 40  ASP A N     1 
ATOM   275  C CA    . ASP A 1 40  ? 122.428 90.532  126.089 1.00 81.84  ? 40  ASP A CA    1 
ATOM   276  C C     . ASP A 1 40  ? 121.986 91.991  125.986 1.00 81.84  ? 40  ASP A C     1 
ATOM   277  O O     . ASP A 1 40  ? 120.926 92.277  125.438 1.00 81.84  ? 40  ASP A O     1 
ATOM   278  C CB    . ASP A 1 40  ? 121.989 89.741  124.874 1.00 105.22 ? 40  ASP A CB    1 
ATOM   279  C CG    . ASP A 1 40  ? 122.765 90.113  123.628 1.00 105.22 ? 40  ASP A CG    1 
ATOM   280  O OD1   . ASP A 1 40  ? 123.620 90.994  123.727 1.00 105.22 ? 40  ASP A OD1   1 
ATOM   281  O OD2   . ASP A 1 40  ? 122.536 89.525  122.560 1.00 105.22 ? 40  ASP A OD2   1 
ATOM   282  N N     . VAL A 1 41  ? 122.760 92.880  126.509 1.00 80.69  ? 41  VAL A N     1 
ATOM   283  C CA    . VAL A 1 41  ? 122.218 94.195  126.716 1.00 80.69  ? 41  VAL A CA    1 
ATOM   284  C C     . VAL A 1 41  ? 122.373 95.056  125.497 1.00 80.69  ? 41  VAL A C     1 
ATOM   285  O O     . VAL A 1 41  ? 123.439 95.134  124.892 1.00 80.69  ? 41  VAL A O     1 
ATOM   286  C CB    . VAL A 1 41  ? 122.847 94.811  127.951 1.00 117.33 ? 41  VAL A CB    1 
ATOM   287  C CG1   . VAL A 1 41  ? 122.459 96.241  128.096 1.00 117.33 ? 41  VAL A CG1   1 
ATOM   288  C CG2   . VAL A 1 41  ? 122.320 94.021  129.129 1.00 117.33 ? 41  VAL A CG2   1 
ATOM   289  N N     . VAL A 1 42  ? 121.291 95.715  125.144 1.00 84.08  ? 42  VAL A N     1 
ATOM   290  C CA    . VAL A 1 42  ? 121.193 96.565  123.974 1.00 84.08  ? 42  VAL A CA    1 
ATOM   291  C C     . VAL A 1 42  ? 120.599 97.921  124.313 1.00 84.08  ? 42  VAL A C     1 
ATOM   292  O O     . VAL A 1 42  ? 119.931 98.080  125.331 1.00 84.08  ? 42  VAL A O     1 
ATOM   293  C CB    . VAL A 1 42  ? 120.334 95.882  122.948 1.00 122.26 ? 42  VAL A CB    1 
ATOM   294  C CG1   . VAL A 1 42  ? 120.981 94.584  122.535 1.00 122.26 ? 42  VAL A CG1   1 
ATOM   295  C CG2   . VAL A 1 42  ? 119.001 95.592  123.548 1.00 122.26 ? 42  VAL A CG2   1 
ATOM   296  N N     . GLY A 1 43  ? 120.817 98.899  123.443 1.00 86.91  ? 43  GLY A N     1 
ATOM   297  C CA    . GLY A 1 43  ? 120.190 100.207 123.578 1.00 86.91  ? 43  GLY A CA    1 
ATOM   298  C C     . GLY A 1 43  ? 120.931 101.062 124.580 1.00 86.91  ? 43  GLY A C     1 
ATOM   299  O O     . GLY A 1 43  ? 121.915 100.631 125.150 1.00 86.91  ? 43  GLY A O     1 
ATOM   300  N N     . ASP A 1 44  ? 120.474 102.288 124.816 1.00 91.20  ? 44  ASP A N     1 
ATOM   301  C CA    . ASP A 1 44  ? 121.197 103.126 125.758 1.00 91.20  ? 44  ASP A CA    1 
ATOM   302  C C     . ASP A 1 44  ? 120.765 102.770 127.154 1.00 91.20  ? 44  ASP A C     1 
ATOM   303  O O     . ASP A 1 44  ? 119.995 103.468 127.800 1.00 91.20  ? 44  ASP A O     1 
ATOM   304  C CB    . ASP A 1 44  ? 120.990 104.602 125.512 1.00 117.26 ? 44  ASP A CB    1 
ATOM   305  C CG    . ASP A 1 44  ? 121.959 105.446 126.333 1.00 117.26 ? 44  ASP A CG    1 
ATOM   306  O OD1   . ASP A 1 44  ? 122.852 104.852 126.947 1.00 117.26 ? 44  ASP A OD1   1 
ATOM   307  O OD2   . ASP A 1 44  ? 121.844 106.675 126.367 1.00 117.26 ? 44  ASP A OD2   1 
ATOM   308  N N     . THR A 1 45  ? 121.297 101.677 127.635 1.00 86.46  ? 45  THR A N     1 
ATOM   309  C CA    . THR A 1 45  ? 120.875 101.149 128.904 1.00 86.46  ? 45  THR A CA    1 
ATOM   310  C C     . THR A 1 45  ? 121.145 102.122 130.003 1.00 86.46  ? 45  THR A C     1 
ATOM   311  O O     . THR A 1 45  ? 120.307 102.319 130.889 1.00 86.46  ? 45  THR A O     1 
ATOM   312  C CB    . THR A 1 45  ? 121.586 99.845  129.180 1.00 121.03 ? 45  THR A CB    1 
ATOM   313  O OG1   . THR A 1 45  ? 121.208 98.914  128.166 1.00 121.03 ? 45  THR A OG1   1 
ATOM   314  C CG2   . THR A 1 45  ? 121.134 99.298  130.477 1.00 121.03 ? 45  THR A CG2   1 
ATOM   315  N N     . ASP A 1 46  ? 122.269 102.791 129.915 1.00 90.98  ? 46  ASP A N     1 
ATOM   316  C CA    . ASP A 1 46  ? 122.769 103.694 130.927 1.00 90.98  ? 46  ASP A CA    1 
ATOM   317  C C     . ASP A 1 46  ? 121.880 104.896 131.195 1.00 90.98  ? 46  ASP A C     1 
ATOM   318  O O     . ASP A 1 46  ? 122.090 105.577 132.191 1.00 90.98  ? 46  ASP A O     1 
ATOM   319  C CB    . ASP A 1 46  ? 124.138 104.200 130.514 1.00 116.97 ? 46  ASP A CB    1 
ATOM   320  C CG    . ASP A 1 46  ? 125.221 103.121 130.549 1.00 116.97 ? 46  ASP A CG    1 
ATOM   321  O OD1   . ASP A 1 46  ? 125.010 102.036 131.098 1.00 116.97 ? 46  ASP A OD1   1 
ATOM   322  O OD2   . ASP A 1 46  ? 126.306 103.378 130.024 1.00 116.97 ? 46  ASP A OD2   1 
ATOM   323  N N     . ILE A 1 47  ? 120.929 105.214 130.329 1.00 85.11  ? 47  ILE A N     1 
ATOM   324  C CA    . ILE A 1 47  ? 120.083 106.346 130.642 1.00 85.11  ? 47  ILE A CA    1 
ATOM   325  C C     . ILE A 1 47  ? 119.170 106.021 131.820 1.00 85.11  ? 47  ILE A C     1 
ATOM   326  O O     . ILE A 1 47  ? 118.872 106.902 132.624 1.00 85.11  ? 47  ILE A O     1 
ATOM   327  C CB    . ILE A 1 47  ? 119.314 106.809 129.411 1.00 125.93 ? 47  ILE A CB    1 
ATOM   328  C CG1   . ILE A 1 47  ? 118.763 108.202 129.662 1.00 125.93 ? 47  ILE A CG1   1 
ATOM   329  C CG2   . ILE A 1 47  ? 118.213 105.944 129.132 1.00 125.93 ? 47  ILE A CG2   1 
ATOM   330  C CD1   . ILE A 1 47  ? 118.123 108.897 128.462 1.00 125.93 ? 47  ILE A CD1   1 
ATOM   331  N N     . PHE A 1 48  ? 118.730 104.770 131.987 1.00 82.99  ? 48  PHE A N     1 
ATOM   332  C CA    . PHE A 1 48  ? 117.863 104.434 133.113 1.00 82.99  ? 48  PHE A CA    1 
ATOM   333  C C     . PHE A 1 48  ? 118.454 103.522 134.164 1.00 82.99  ? 48  PHE A C     1 
ATOM   334  O O     . PHE A 1 48  ? 117.925 103.486 135.279 1.00 82.99  ? 48  PHE A O     1 
ATOM   335  C CB    . PHE A 1 48  ? 116.573 103.808 132.633 1.00 115.76 ? 48  PHE A CB    1 
ATOM   336  C CG    . PHE A 1 48  ? 115.686 104.765 132.094 1.00 115.76 ? 48  PHE A CG    1 
ATOM   337  C CD1   . PHE A 1 48  ? 115.053 105.597 132.916 1.00 115.76 ? 48  PHE A CD1   1 
ATOM   338  C CD2   . PHE A 1 48  ? 115.488 104.871 130.791 1.00 115.76 ? 48  PHE A CD2   1 
ATOM   339  C CE1   . PHE A 1 48  ? 114.233 106.530 132.442 1.00 115.76 ? 48  PHE A CE1   1 
ATOM   340  C CE2   . PHE A 1 48  ? 114.672 105.795 130.314 1.00 115.76 ? 48  PHE A CE2   1 
ATOM   341  C CZ    . PHE A 1 48  ? 114.051 106.636 131.143 1.00 115.76 ? 48  PHE A CZ    1 
ATOM   342  N N     . PHE A 1 49  ? 119.518 102.801 133.881 1.00 85.22  ? 49  PHE A N     1 
ATOM   343  C CA    . PHE A 1 49  ? 120.043 101.866 134.839 1.00 85.22  ? 49  PHE A CA    1 
ATOM   344  C C     . PHE A 1 49  ? 121.457 102.208 135.225 1.00 85.22  ? 49  PHE A C     1 
ATOM   345  O O     . PHE A 1 49  ? 122.265 102.541 134.384 1.00 85.22  ? 49  PHE A O     1 
ATOM   346  C CB    . PHE A 1 49  ? 120.073 100.515 134.264 1.00 118.87 ? 49  PHE A CB    1 
ATOM   347  C CG    . PHE A 1 49  ? 118.773 99.960  133.911 1.00 118.87 ? 49  PHE A CG    1 
ATOM   348  C CD1   . PHE A 1 49  ? 118.242 100.173 132.707 1.00 118.87 ? 49  PHE A CD1   1 
ATOM   349  C CD2   . PHE A 1 49  ? 118.145 99.128  134.760 1.00 118.87 ? 49  PHE A CD2   1 
ATOM   350  C CE1   . PHE A 1 49  ? 117.072 99.625  132.370 1.00 118.87 ? 49  PHE A CE1   1 
ATOM   351  C CE2   . PHE A 1 49  ? 116.975 98.572  134.430 1.00 118.87 ? 49  PHE A CE2   1 
ATOM   352  C CZ    . PHE A 1 49  ? 116.442 98.814  133.229 1.00 118.87 ? 49  PHE A CZ    1 
ATOM   353  N N     . ASN A 1 50  ? 121.806 102.046 136.468 1.00 88.10  ? 50  ASN A N     1 
ATOM   354  C CA    . ASN A 1 50  ? 123.198 102.213 136.775 1.00 88.10  ? 50  ASN A CA    1 
ATOM   355  C C     . ASN A 1 50  ? 123.806 100.869 136.542 1.00 88.10  ? 50  ASN A C     1 
ATOM   356  O O     . ASN A 1 50  ? 123.087 99.896  136.329 1.00 88.10  ? 50  ASN A O     1 
ATOM   357  C CB    . ASN A 1 50  ? 123.385 102.664 138.207 1.00 119.35 ? 50  ASN A CB    1 
ATOM   358  C CG    . ASN A 1 50  ? 124.695 103.278 138.444 1.00 119.35 ? 50  ASN A CG    1 
ATOM   359  O OD1   . ASN A 1 50  ? 125.557 103.265 137.571 1.00 119.35 ? 50  ASN A OD1   1 
ATOM   360  N ND2   . ASN A 1 50  ? 124.878 103.837 139.621 1.00 119.35 ? 50  ASN A ND2   1 
ATOM   361  N N     . THR A 1 51  ? 125.117 100.749 136.659 1.00 92.31  ? 51  THR A N     1 
ATOM   362  C CA    . THR A 1 51  ? 125.698 99.429  136.512 1.00 92.31  ? 51  THR A CA    1 
ATOM   363  C C     . THR A 1 51  ? 126.739 99.155  137.566 1.00 92.31  ? 51  THR A C     1 
ATOM   364  O O     . THR A 1 51  ? 127.677 99.923  137.734 1.00 92.31  ? 51  THR A O     1 
ATOM   365  C CB    . THR A 1 51  ? 126.329 99.246  135.152 1.00 129.22 ? 51  THR A CB    1 
ATOM   366  O OG1   . THR A 1 51  ? 125.382 99.560  134.135 1.00 129.22 ? 51  THR A OG1   1 
ATOM   367  C CG2   . THR A 1 51  ? 126.727 97.799  134.985 1.00 129.22 ? 51  THR A CG2   1 
ATOM   368  N N     . ILE A 1 52  ? 126.603 98.046  138.250 1.00 96.61  ? 52  ILE A N     1 
ATOM   369  C CA    . ILE A 1 52  ? 127.634 97.571  139.146 1.00 96.61  ? 52  ILE A CA    1 
ATOM   370  C C     . ILE A 1 52  ? 127.908 96.128  138.782 1.00 96.61  ? 52  ILE A C     1 
ATOM   371  O O     . ILE A 1 52  ? 126.999 95.298  138.814 1.00 96.61  ? 52  ILE A O     1 
ATOM   372  C CB    . ILE A 1 52  ? 127.219 97.689  140.608 1.00 142.95 ? 52  ILE A CB    1 
ATOM   373  C CG1   . ILE A 1 52  ? 126.950 99.157  140.924 1.00 142.95 ? 52  ILE A CG1   1 
ATOM   374  C CG2   . ILE A 1 52  ? 128.276 97.086  141.496 1.00 142.95 ? 52  ILE A CG2   1 
ATOM   375  C CD1   . ILE A 1 52  ? 126.404 99.440  142.319 1.00 142.95 ? 52  ILE A CD1   1 
ATOM   376  N N     . GLY A 1 53  ? 129.139 95.813  138.456 1.00 99.85  ? 53  GLY A N     1 
ATOM   377  C CA    . GLY A 1 53  ? 129.387 94.449  138.040 1.00 99.85  ? 53  GLY A CA    1 
ATOM   378  C C     . GLY A 1 53  ? 128.591 94.170  136.793 1.00 99.85  ? 53  GLY A C     1 
ATOM   379  O O     . GLY A 1 53  ? 128.665 94.909  135.816 1.00 99.85  ? 53  GLY A O     1 
ATOM   380  N N     . ASP A 1 54  ? 127.823 93.096  136.814 1.00 98.82  ? 54  ASP A N     1 
ATOM   381  C CA    . ASP A 1 54  ? 127.003 92.712  135.689 1.00 98.82  ? 54  ASP A CA    1 
ATOM   382  C C     . ASP A 1 54  ? 125.530 92.921  135.987 1.00 98.82  ? 54  ASP A C     1 
ATOM   383  O O     . ASP A 1 54  ? 124.664 92.379  135.284 1.00 98.82  ? 54  ASP A O     1 
ATOM   384  C CB    . ASP A 1 54  ? 127.291 91.265  135.338 1.00 127.05 ? 54  ASP A CB    1 
ATOM   385  C CG    . ASP A 1 54  ? 127.054 90.370  136.497 1.00 127.05 ? 54  ASP A CG    1 
ATOM   386  O OD1   . ASP A 1 54  ? 126.919 90.892  137.603 1.00 127.05 ? 54  ASP A OD1   1 
ATOM   387  O OD2   . ASP A 1 54  ? 126.976 89.154  136.332 1.00 127.05 ? 54  ASP A OD2   1 
ATOM   388  N N     . LYS A 1 55  ? 125.238 93.704  137.021 1.00 94.13  ? 55  LYS A N     1 
ATOM   389  C CA    . LYS A 1 55  ? 123.885 93.993  137.471 1.00 94.13  ? 55  LYS A CA    1 
ATOM   390  C C     . LYS A 1 55  ? 123.412 95.369  137.036 1.00 94.13  ? 55  LYS A C     1 
ATOM   391  O O     . LYS A 1 55  ? 124.063 96.380  137.312 1.00 94.13  ? 55  LYS A O     1 
ATOM   392  C CB    . LYS A 1 55  ? 123.798 93.911  138.989 1.00 141.07 ? 55  LYS A CB    1 
ATOM   393  C CG    . LYS A 1 55  ? 122.407 94.129  139.531 1.00 141.07 ? 55  LYS A CG    1 
ATOM   394  C CD    . LYS A 1 55  ? 122.369 94.136  141.048 1.00 141.07 ? 55  LYS A CD    1 
ATOM   395  C CE    . LYS A 1 55  ? 120.930 94.308  141.567 1.00 141.07 ? 55  LYS A CE    1 
ATOM   396  N NZ    . LYS A 1 55  ? 120.872 94.525  143.044 1.00 141.07 ? 55  LYS A NZ    1 
ATOM   397  N N     . TYR A 1 56  ? 122.255 95.421  136.431 1.00 92.85  ? 56  TYR A N     1 
ATOM   398  C CA    . TYR A 1 56  ? 121.681 96.682  136.086 1.00 92.85  ? 56  TYR A CA    1 
ATOM   399  C C     . TYR A 1 56  ? 120.718 97.095  137.164 1.00 92.85  ? 56  TYR A C     1 
ATOM   400  O O     . TYR A 1 56  ? 119.828 96.337  137.541 1.00 92.85  ? 56  TYR A O     1 
ATOM   401  C CB    . TYR A 1 56  ? 121.008 96.577  134.759 1.00 128.51 ? 56  TYR A CB    1 
ATOM   402  C CG    . TYR A 1 56  ? 122.029 96.523  133.780 1.00 128.51 ? 56  TYR A CG    1 
ATOM   403  C CD1   . TYR A 1 56  ? 122.572 97.669  133.326 1.00 128.51 ? 56  TYR A CD1   1 
ATOM   404  C CD2   . TYR A 1 56  ? 122.478 95.362  133.329 1.00 128.51 ? 56  TYR A CD2   1 
ATOM   405  C CE1   . TYR A 1 56  ? 123.546 97.647  132.431 1.00 128.51 ? 56  TYR A CE1   1 
ATOM   406  C CE2   . TYR A 1 56  ? 123.460 95.330  132.429 1.00 128.51 ? 56  TYR A CE2   1 
ATOM   407  C CZ    . TYR A 1 56  ? 123.987 96.469  131.978 1.00 128.51 ? 56  TYR A CZ    1 
ATOM   408  O OH    . TYR A 1 56  ? 124.997 96.428  131.063 1.00 128.51 ? 56  TYR A OH    1 
ATOM   409  N N     . ILE A 1 57  ? 120.901 98.289  137.667 1.00 85.89  ? 57  ILE A N     1 
ATOM   410  C CA    . ILE A 1 57  ? 120.140 98.757  138.801 1.00 85.89  ? 57  ILE A CA    1 
ATOM   411  C C     . ILE A 1 57  ? 119.294 99.939  138.410 1.00 85.89  ? 57  ILE A C     1 
ATOM   412  O O     . ILE A 1 57  ? 119.829 101.019 138.194 1.00 85.89  ? 57  ILE A O     1 
ATOM   413  C CB    . ILE A 1 57  ? 121.091 99.164  139.893 1.00 127.09 ? 57  ILE A CB    1 
ATOM   414  C CG1   . ILE A 1 57  ? 121.969 97.995  140.214 1.00 127.09 ? 57  ILE A CG1   1 
ATOM   415  C CG2   . ILE A 1 57  ? 120.330 99.640  141.052 1.00 127.09 ? 57  ILE A CG2   1 
ATOM   416  C CD1   . ILE A 1 57  ? 123.172 98.336  140.997 1.00 127.09 ? 57  ILE A CD1   1 
ATOM   417  N N     . PRO A 1 58  ? 118.014 99.799  138.329 1.00 86.50  ? 58  PRO A N     1 
ATOM   418  C CA    . PRO A 1 58  ? 117.179 100.871 137.869 1.00 86.50  ? 58  PRO A CA    1 
ATOM   419  C C     . PRO A 1 58  ? 117.316 102.026 138.813 1.00 86.50  ? 58  PRO A C     1 
ATOM   420  O O     . PRO A 1 58  ? 117.255 101.842 140.008 1.00 86.50  ? 58  PRO A O     1 
ATOM   421  C CB    . PRO A 1 58  ? 115.803 100.260 137.936 1.00 269.80 ? 58  PRO A CB    1 
ATOM   422  C CG    . PRO A 1 58  ? 115.922 99.250  138.945 1.00 269.80 ? 58  PRO A CG    1 
ATOM   423  C CD    . PRO A 1 58  ? 117.277 98.692  138.850 1.00 269.80 ? 58  PRO A CD    1 
ATOM   424  N N     . ARG A 1 59  ? 117.482 103.229 138.274 1.00 89.79  ? 59  ARG A N     1 
ATOM   425  C CA    . ARG A 1 59  ? 117.692 104.392 139.112 1.00 89.79  ? 59  ARG A CA    1 
ATOM   426  C C     . ARG A 1 59  ? 116.373 104.937 139.568 1.00 89.79  ? 59  ARG A C     1 
ATOM   427  O O     . ARG A 1 59  ? 115.932 106.003 139.155 1.00 89.79  ? 59  ARG A O     1 
ATOM   428  C CB    . ARG A 1 59  ? 118.483 105.462 138.409 1.00 131.82 ? 59  ARG A CB    1 
ATOM   429  C CG    . ARG A 1 59  ? 119.907 105.065 138.332 1.00 131.82 ? 59  ARG A CG    1 
ATOM   430  C CD    . ARG A 1 59  ? 120.793 106.083 137.752 1.00 131.82 ? 59  ARG A CD    1 
ATOM   431  N NE    . ARG A 1 59  ? 120.486 106.284 136.371 1.00 131.82 ? 59  ARG A NE    1 
ATOM   432  C CZ    . ARG A 1 59  ? 121.376 106.579 135.449 1.00 131.82 ? 59  ARG A CZ    1 
ATOM   433  N NH1   . ARG A 1 59  ? 122.652 106.710 135.731 1.00 131.82 ? 59  ARG A NH1   1 
ATOM   434  N NH2   . ARG A 1 59  ? 120.973 106.713 134.204 1.00 131.82 ? 59  ARG A NH2   1 
ATOM   435  N N     . ALA A 1 60  ? 115.765 104.184 140.446 1.00 93.59  ? 60  ALA A N     1 
ATOM   436  C CA    . ALA A 1 60  ? 114.472 104.508 140.968 1.00 93.59  ? 60  ALA A CA    1 
ATOM   437  C C     . ALA A 1 60  ? 114.555 104.850 142.432 1.00 93.59  ? 60  ALA A C     1 
ATOM   438  O O     . ALA A 1 60  ? 115.387 104.324 143.165 1.00 93.59  ? 60  ALA A O     1 
ATOM   439  C CB    . ALA A 1 60  ? 113.526 103.350 140.765 1.00 127.62 ? 60  ALA A CB    1 
ATOM   440  N N     . VAL A 1 61  ? 113.671 105.735 142.834 1.00 94.10  ? 61  VAL A N     1 
ATOM   441  C CA    . VAL A 1 61  ? 113.428 106.138 144.203 1.00 94.10  ? 61  VAL A CA    1 
ATOM   442  C C     . VAL A 1 61  ? 112.022 105.666 144.516 1.00 94.10  ? 61  VAL A C     1 
ATOM   443  O O     . VAL A 1 61  ? 111.088 106.045 143.810 1.00 94.10  ? 61  VAL A O     1 
ATOM   444  C CB    . VAL A 1 61  ? 113.550 107.654 144.318 1.00 136.83 ? 61  VAL A CB    1 
ATOM   445  C CG1   . VAL A 1 61  ? 113.357 108.107 145.722 1.00 136.83 ? 61  VAL A CG1   1 
ATOM   446  C CG2   . VAL A 1 61  ? 114.877 108.086 143.793 1.00 136.83 ? 61  VAL A CG2   1 
ATOM   447  N N     . VAL A 1 62  ? 111.839 104.832 145.530 1.00 97.11  ? 62  VAL A N     1 
ATOM   448  C CA    . VAL A 1 62  ? 110.526 104.279 145.795 1.00 97.11  ? 62  VAL A CA    1 
ATOM   449  C C     . VAL A 1 62  ? 109.945 104.899 147.045 1.00 97.11  ? 62  VAL A C     1 
ATOM   450  O O     . VAL A 1 62  ? 110.473 104.703 148.137 1.00 97.11  ? 62  VAL A O     1 
ATOM   451  C CB    . VAL A 1 62  ? 110.615 102.785 145.944 1.00 141.20 ? 62  VAL A CB    1 
ATOM   452  C CG1   . VAL A 1 62  ? 109.275 102.203 146.272 1.00 141.20 ? 62  VAL A CG1   1 
ATOM   453  C CG2   . VAL A 1 62  ? 111.182 102.226 144.690 1.00 141.20 ? 62  VAL A CG2   1 
ATOM   454  N N     . VAL A 1 63  ? 108.844 105.609 146.918 1.00 98.85  ? 63  VAL A N     1 
ATOM   455  C CA    . VAL A 1 63  ? 108.349 106.433 148.009 1.00 98.85  ? 63  VAL A CA    1 
ATOM   456  C C     . VAL A 1 63  ? 106.928 106.153 148.380 1.00 98.85  ? 63  VAL A C     1 
ATOM   457  O O     . VAL A 1 63  ? 106.036 106.163 147.527 1.00 98.85  ? 63  VAL A O     1 
ATOM   458  C CB    . VAL A 1 63  ? 108.447 107.888 147.626 1.00 143.73 ? 63  VAL A CB    1 
ATOM   459  C CG1   . VAL A 1 63  ? 107.901 108.729 148.685 1.00 143.73 ? 63  VAL A CG1   1 
ATOM   460  C CG2   . VAL A 1 63  ? 109.859 108.219 147.333 1.00 143.73 ? 63  VAL A CG2   1 
ATOM   461  N N     . ASP A 1 64  ? 106.688 105.987 149.658 1.00 108.40 ? 64  ASP A N     1 
ATOM   462  C CA    . ASP A 1 64  ? 105.327 105.990 150.133 1.00 108.40 ? 64  ASP A CA    1 
ATOM   463  C C     . ASP A 1 64  ? 105.345 106.493 151.542 1.00 108.40 ? 64  ASP A C     1 
ATOM   464  O O     . ASP A 1 64  ? 106.384 106.862 152.070 1.00 108.40 ? 64  ASP A O     1 
ATOM   465  C CB    . ASP A 1 64  ? 104.657 104.644 150.043 1.00 139.37 ? 64  ASP A CB    1 
ATOM   466  C CG    . ASP A 1 64  ? 103.144 104.766 149.919 1.00 139.37 ? 64  ASP A CG    1 
ATOM   467  O OD1   . ASP A 1 64  ? 102.495 105.148 150.896 1.00 139.37 ? 64  ASP A OD1   1 
ATOM   468  O OD2   . ASP A 1 64  ? 102.605 104.527 148.840 1.00 139.37 ? 64  ASP A OD2   1 
ATOM   469  N N     . LEU A 1 65  ? 104.187 106.599 152.120 1.00 112.18 ? 65  LEU A N     1 
ATOM   470  C CA    . LEU A 1 65  ? 104.159 106.920 153.505 1.00 112.18 ? 65  LEU A CA    1 
ATOM   471  C C     . LEU A 1 65  ? 103.890 105.665 154.279 1.00 112.18 ? 65  LEU A C     1 
ATOM   472  O O     . LEU A 1 65  ? 104.439 105.474 155.363 1.00 112.18 ? 65  LEU A O     1 
ATOM   473  C CB    . LEU A 1 65  ? 103.104 107.988 153.760 1.00 165.98 ? 65  LEU A CB    1 
ATOM   474  C CG    . LEU A 1 65  ? 103.316 109.311 153.034 1.00 165.98 ? 65  LEU A CG    1 
ATOM   475  C CD1   . LEU A 1 65  ? 102.143 110.212 153.269 1.00 165.98 ? 65  LEU A CD1   1 
ATOM   476  C CD2   . LEU A 1 65  ? 104.576 110.011 153.501 1.00 165.98 ? 65  LEU A CD2   1 
ATOM   477  N N     . GLU A 1 66  ? 103.119 104.776 153.696 1.00 118.09 ? 66  GLU A N     1 
ATOM   478  C CA    . GLU A 1 66  ? 102.746 103.562 154.392 1.00 118.09 ? 66  GLU A CA    1 
ATOM   479  C C     . GLU A 1 66  ? 103.899 102.569 154.388 1.00 118.09 ? 66  GLU A C     1 
ATOM   480  O O     . GLU A 1 66  ? 104.395 102.207 153.312 1.00 118.09 ? 66  GLU A O     1 
ATOM   481  C CB    . GLU A 1 66  ? 101.520 102.927 153.765 1.00 158.61 ? 66  GLU A CB    1 
ATOM   482  C CG    . GLU A 1 66  ? 101.084 101.702 154.518 1.00 158.61 ? 66  GLU A CG    1 
ATOM   483  C CD    . GLU A 1 66  ? 99.840  101.082 153.986 1.00 158.61 ? 66  GLU A CD    1 
ATOM   484  O OE1   . GLU A 1 66  ? 99.287  101.592 153.016 1.00 158.61 ? 66  GLU A OE1   1 
ATOM   485  O OE2   . GLU A 1 66  ? 99.412  100.075 154.546 1.00 158.61 ? 66  GLU A OE2   1 
ATOM   486  N N     . PRO A 1 67  ? 104.342 102.114 155.555 1.00 119.09 ? 67  PRO A N     1 
ATOM   487  C CA    . PRO A 1 67  ? 105.446 101.152 155.660 1.00 119.09 ? 67  PRO A CA    1 
ATOM   488  C C     . PRO A 1 67  ? 105.287 99.977  154.733 1.00 119.09 ? 67  PRO A C     1 
ATOM   489  O O     . PRO A 1 67  ? 106.203 99.623  153.982 1.00 119.09 ? 67  PRO A O     1 
ATOM   490  C CB    . PRO A 1 67  ? 105.350 100.730 157.121 1.00 371.45 ? 67  PRO A CB    1 
ATOM   491  C CG    . PRO A 1 67  ? 104.808 101.957 157.807 1.00 371.45 ? 67  PRO A CG    1 
ATOM   492  C CD    . PRO A 1 67  ? 103.825 102.544 156.848 1.00 371.45 ? 67  PRO A CD    1 
ATOM   493  N N     . ALA A 1 68  ? 104.081 99.438  154.700 1.00 121.11 ? 68  ALA A N     1 
ATOM   494  C CA    . ALA A 1 68  ? 103.792 98.252  153.920 1.00 121.11 ? 68  ALA A CA    1 
ATOM   495  C C     . ALA A 1 68  ? 103.925 98.471  152.431 1.00 121.11 ? 68  ALA A C     1 
ATOM   496  O O     . ALA A 1 68  ? 104.261 97.537  151.702 1.00 121.11 ? 68  ALA A O     1 
ATOM   497  C CB    . ALA A 1 68  ? 102.379 97.787  154.223 1.00 165.15 ? 68  ALA A CB    1 
ATOM   498  N N     . VAL A 1 69  ? 103.604 99.658  151.935 1.00 120.12 ? 69  VAL A N     1 
ATOM   499  C CA    . VAL A 1 69  ? 103.606 99.809  150.489 1.00 120.12 ? 69  VAL A CA    1 
ATOM   500  C C     . VAL A 1 69  ? 105.006 99.717  149.952 1.00 120.12 ? 69  VAL A C     1 
ATOM   501  O O     . VAL A 1 69  ? 105.242 99.096  148.914 1.00 120.12 ? 69  VAL A O     1 
ATOM   502  C CB    . VAL A 1 69  ? 102.947 101.118 150.057 1.00 174.66 ? 69  VAL A CB    1 
ATOM   503  C CG1   . VAL A 1 69  ? 103.160 101.334 148.544 1.00 174.66 ? 69  VAL A CG1   1 
ATOM   504  C CG2   . VAL A 1 69  ? 101.491 101.033 150.376 1.00 174.66 ? 69  VAL A CG2   1 
ATOM   505  N N     . VAL A 1 70  ? 105.950 100.347 150.621 1.00 122.04 ? 70  VAL A N     1 
ATOM   506  C CA    . VAL A 1 70  ? 107.287 100.226 150.090 1.00 122.04 ? 70  VAL A CA    1 
ATOM   507  C C     . VAL A 1 70  ? 107.901 98.888  150.493 1.00 122.04 ? 70  VAL A C     1 
ATOM   508  O O     . VAL A 1 70  ? 108.572 98.248  149.685 1.00 122.04 ? 70  VAL A O     1 
ATOM   509  C CB    . VAL A 1 70  ? 108.157 101.432 150.485 1.00 177.45 ? 70  VAL A CB    1 
ATOM   510  C CG1   . VAL A 1 70  ? 107.466 102.700 150.102 1.00 177.45 ? 70  VAL A CG1   1 
ATOM   511  C CG2   . VAL A 1 70  ? 108.504 101.402 151.947 1.00 177.45 ? 70  VAL A CG2   1 
ATOM   512  N N     . GLU A 1 71  ? 107.643 98.397  151.708 1.00 124.62 ? 71  GLU A N     1 
ATOM   513  C CA    . GLU A 1 71  ? 108.262 97.136  152.116 1.00 124.62 ? 71  GLU A CA    1 
ATOM   514  C C     . GLU A 1 71  ? 107.823 95.972  151.245 1.00 124.62 ? 71  GLU A C     1 
ATOM   515  O O     . GLU A 1 71  ? 108.628 95.096  150.931 1.00 124.62 ? 71  GLU A O     1 
ATOM   516  C CB    . GLU A 1 71  ? 107.938 96.823  153.570 1.00 167.38 ? 71  GLU A CB    1 
ATOM   517  C CG    . GLU A 1 71  ? 108.640 97.706  154.583 1.00 167.38 ? 71  GLU A CG    1 
ATOM   518  C CD    . GLU A 1 71  ? 108.152 97.461  155.990 1.00 167.38 ? 71  GLU A CD    1 
ATOM   519  O OE1   . GLU A 1 71  ? 107.218 96.675  156.160 1.00 167.38 ? 71  GLU A OE1   1 
ATOM   520  O OE2   . GLU A 1 71  ? 108.699 98.057  156.920 1.00 167.38 ? 71  GLU A OE2   1 
ATOM   521  N N     . ASN A 1 72  ? 106.567 95.954  150.822 1.00 121.12 ? 72  ASN A N     1 
ATOM   522  C CA    . ASN A 1 72  ? 106.041 94.829  150.080 1.00 121.12 ? 72  ASN A CA    1 
ATOM   523  C C     . ASN A 1 72  ? 106.459 94.828  148.631 1.00 121.12 ? 72  ASN A C     1 
ATOM   524  O O     . ASN A 1 72  ? 106.118 93.895  147.896 1.00 121.12 ? 72  ASN A O     1 
ATOM   525  C CB    . ASN A 1 72  ? 104.543 94.809  150.192 1.00 164.08 ? 72  ASN A CB    1 
ATOM   526  C CG    . ASN A 1 72  ? 104.078 94.522  151.615 1.00 164.08 ? 72  ASN A CG    1 
ATOM   527  O OD1   . ASN A 1 72  ? 104.818 94.020  152.479 1.00 164.08 ? 72  ASN A OD1   1 
ATOM   528  N ND2   . ASN A 1 72  ? 102.829 94.839  151.862 1.00 164.08 ? 72  ASN A ND2   1 
ATOM   529  N N     . ILE A 1 73  ? 107.208 95.837  148.203 1.00 118.18 ? 73  ILE A N     1 
ATOM   530  C CA    . ILE A 1 73  ? 107.715 95.835  146.849 1.00 118.18 ? 73  ILE A CA    1 
ATOM   531  C C     . ILE A 1 73  ? 108.653 94.652  146.694 1.00 118.18 ? 73  ILE A C     1 
ATOM   532  O O     . ILE A 1 73  ? 108.816 94.123  145.590 1.00 118.18 ? 73  ILE A O     1 
ATOM   533  C CB    . ILE A 1 73  ? 108.412 97.171  146.515 1.00 174.86 ? 73  ILE A CB    1 
ATOM   534  C CG1   . ILE A 1 73  ? 108.421 97.408  145.004 1.00 174.86 ? 73  ILE A CG1   1 
ATOM   535  C CG2   . ILE A 1 73  ? 109.857 97.165  147.046 1.00 174.86 ? 73  ILE A CG2   1 
ATOM   536  C CD1   . ILE A 1 73  ? 108.824 98.819  144.552 1.00 174.86 ? 73  ILE A CD1   1 
ATOM   537  N N     . ARG A 1 74  ? 109.233 94.197  147.808 1.00 117.65 ? 74  ARG A N     1 
ATOM   538  C CA    . ARG A 1 74  ? 110.149 93.070  147.826 1.00 117.65 ? 74  ARG A CA    1 
ATOM   539  C C     . ARG A 1 74  ? 109.471 91.786  147.425 1.00 117.65 ? 74  ARG A C     1 
ATOM   540  O O     . ARG A 1 74  ? 110.152 90.801  147.152 1.00 117.65 ? 74  ARG A O     1 
ATOM   541  C CB    . ARG A 1 74  ? 110.720 92.854  149.223 1.00 172.73 ? 74  ARG A CB    1 
ATOM   542  C CG    . ARG A 1 74  ? 109.717 92.215  150.159 1.00 172.73 ? 74  ARG A CG    1 
ATOM   543  C CD    . ARG A 1 74  ? 110.129 92.157  151.594 1.00 172.73 ? 74  ARG A CD    1 
ATOM   544  N NE    . ARG A 1 74  ? 109.122 91.423  152.367 1.00 172.73 ? 74  ARG A NE    1 
ATOM   545  C CZ    . ARG A 1 74  ? 107.987 91.940  152.837 1.00 172.73 ? 74  ARG A CZ    1 
ATOM   546  N NH1   . ARG A 1 74  ? 107.688 93.212  152.663 1.00 172.73 ? 74  ARG A NH1   1 
ATOM   547  N NH2   . ARG A 1 74  ? 107.130 91.156  153.490 1.00 172.73 ? 74  ARG A NH2   1 
ATOM   548  N N     . GLU A 1 75  ? 108.158 91.733  147.489 1.00 116.08 ? 75  GLU A N     1 
ATOM   549  C CA    . GLU A 1 75  ? 107.462 90.524  147.117 1.00 116.08 ? 75  GLU A CA    1 
ATOM   550  C C     . GLU A 1 75  ? 106.884 90.635  145.727 1.00 116.08 ? 75  GLU A C     1 
ATOM   551  O O     . GLU A 1 75  ? 106.883 89.659  144.978 1.00 116.08 ? 75  GLU A O     1 
ATOM   552  C CB    . GLU A 1 75  ? 106.349 90.205  148.120 1.00 155.91 ? 75  GLU A CB    1 
ATOM   553  C CG    . GLU A 1 75  ? 106.846 89.898  149.541 1.00 155.91 ? 75  GLU A CG    1 
ATOM   554  C CD    . GLU A 1 75  ? 105.740 89.535  150.501 1.00 155.91 ? 75  GLU A CD    1 
ATOM   555  O OE1   . GLU A 1 75  ? 104.577 89.745  150.162 1.00 155.91 ? 75  GLU A OE1   1 
ATOM   556  O OE2   . GLU A 1 75  ? 106.039 89.035  151.590 1.00 155.91 ? 75  GLU A OE2   1 
ATOM   557  N N     . LYS A 1 76  ? 106.433 91.821  145.355 1.00 115.15 ? 76  LYS A N     1 
ATOM   558  C CA    . LYS A 1 76  ? 105.849 92.000  144.035 1.00 115.15 ? 76  LYS A CA    1 
ATOM   559  C C     . LYS A 1 76  ? 106.910 92.097  142.941 1.00 115.15 ? 76  LYS A C     1 
ATOM   560  O O     . LYS A 1 76  ? 106.753 91.491  141.878 1.00 115.15 ? 76  LYS A O     1 
ATOM   561  C CB    . LYS A 1 76  ? 104.961 93.236  144.031 1.00 172.57 ? 76  LYS A CB    1 
ATOM   562  C CG    . LYS A 1 76  ? 104.255 93.513  142.715 1.00 172.57 ? 76  LYS A CG    1 
ATOM   563  C CD    . LYS A 1 76  ? 103.200 92.493  142.379 1.00 172.57 ? 76  LYS A CD    1 
ATOM   564  C CE    . LYS A 1 76  ? 102.438 92.916  141.124 1.00 172.57 ? 76  LYS A CE    1 
ATOM   565  N NZ    . LYS A 1 76  ? 101.403 91.921  140.731 1.00 172.57 ? 76  LYS A NZ    1 
ATOM   566  N N     . PHE A 1 77  ? 107.981 92.861  143.160 1.00 111.45 ? 77  PHE A N     1 
ATOM   567  C CA    . PHE A 1 77  ? 109.033 93.011  142.163 1.00 111.45 ? 77  PHE A CA    1 
ATOM   568  C C     . PHE A 1 77  ? 110.376 92.500  142.644 1.00 111.45 ? 77  PHE A C     1 
ATOM   569  O O     . PHE A 1 77  ? 111.229 92.153  141.821 1.00 111.45 ? 77  PHE A O     1 
ATOM   570  C CB    . PHE A 1 77  ? 109.127 94.475  141.735 1.00 155.45 ? 77  PHE A CB    1 
ATOM   571  C CG    . PHE A 1 77  ? 107.872 94.953  141.119 1.00 155.45 ? 77  PHE A CG    1 
ATOM   572  C CD1   . PHE A 1 77  ? 107.533 94.551  139.865 1.00 155.45 ? 77  PHE A CD1   1 
ATOM   573  C CD2   . PHE A 1 77  ? 107.000 95.754  141.815 1.00 155.45 ? 77  PHE A CD2   1 
ATOM   574  C CE1   . PHE A 1 77  ? 106.351 94.945  139.292 1.00 155.45 ? 77  PHE A CE1   1 
ATOM   575  C CE2   . PHE A 1 77  ? 105.818 96.161  141.251 1.00 155.45 ? 77  PHE A CE2   1 
ATOM   576  C CZ    . PHE A 1 77  ? 105.490 95.747  139.987 1.00 155.45 ? 77  PHE A CZ    1 
ATOM   577  N N     . GLY A 1 78  ? 110.552 92.394  143.948 1.00 110.02 ? 78  GLY A N     1 
ATOM   578  C CA    . GLY A 1 78  ? 111.758 91.844  144.531 1.00 110.02 ? 78  GLY A CA    1 
ATOM   579  C C     . GLY A 1 78  ? 113.009 92.644  144.270 1.00 110.02 ? 78  GLY A C     1 
ATOM   580  O O     . GLY A 1 78  ? 113.061 93.863  144.472 1.00 110.02 ? 78  GLY A O     1 
ATOM   581  N N     . THR A 1 79  ? 114.013 91.923  143.777 1.00 100.25 ? 79  THR A N     1 
ATOM   582  C CA    . THR A 1 79  ? 115.347 92.415  143.513 1.00 100.25 ? 79  THR A CA    1 
ATOM   583  C C     . THR A 1 79  ? 115.363 93.512  142.469 1.00 100.25 ? 79  THR A C     1 
ATOM   584  O O     . THR A 1 79  ? 116.343 94.242  142.358 1.00 100.25 ? 79  THR A O     1 
ATOM   585  C CB    . THR A 1 79  ? 116.216 91.237  143.084 1.00 140.33 ? 79  THR A CB    1 
ATOM   586  O OG1   . THR A 1 79  ? 116.221 90.268  144.134 1.00 140.33 ? 79  THR A OG1   1 
ATOM   587  C CG2   . THR A 1 79  ? 117.664 91.656  142.791 1.00 140.33 ? 79  THR A CG2   1 
ATOM   588  N N     . LEU A 1 80  ? 114.291 93.665  141.710 1.00 99.97  ? 80  LEU A N     1 
ATOM   589  C CA    . LEU A 1 80  ? 114.253 94.738  140.728 1.00 99.97  ? 80  LEU A CA    1 
ATOM   590  C C     . LEU A 1 80  ? 114.569 96.094  141.363 1.00 99.97  ? 80  LEU A C     1 
ATOM   591  O O     . LEU A 1 80  ? 115.216 96.926  140.728 1.00 99.97  ? 80  LEU A O     1 
ATOM   592  C CB    . LEU A 1 80  ? 112.881 94.766  140.035 1.00 147.92 ? 80  LEU A CB    1 
ATOM   593  C CG    . LEU A 1 80  ? 112.592 95.774  138.898 1.00 147.92 ? 80  LEU A CG    1 
ATOM   594  C CD1   . LEU A 1 80  ? 113.538 95.577  137.735 1.00 147.92 ? 80  LEU A CD1   1 
ATOM   595  C CD2   . LEU A 1 80  ? 111.131 95.623  138.413 1.00 147.92 ? 80  LEU A CD2   1 
ATOM   596  N N     . PHE A 1 81  ? 114.132 96.358  142.603 1.00 99.84  ? 81  PHE A N     1 
ATOM   597  C CA    . PHE A 1 81  ? 114.399 97.659  143.232 1.00 99.84  ? 81  PHE A CA    1 
ATOM   598  C C     . PHE A 1 81  ? 115.263 97.493  144.467 1.00 99.84  ? 81  PHE A C     1 
ATOM   599  O O     . PHE A 1 81  ? 114.775 97.046  145.507 1.00 99.84  ? 81  PHE A O     1 
ATOM   600  C CB    . PHE A 1 81  ? 113.117 98.352  143.649 1.00 139.26 ? 81  PHE A CB    1 
ATOM   601  C CG    . PHE A 1 81  ? 112.209 98.640  142.552 1.00 139.26 ? 81  PHE A CG    1 
ATOM   602  C CD1   . PHE A 1 81  ? 112.284 99.814  141.894 1.00 139.26 ? 81  PHE A CD1   1 
ATOM   603  C CD2   . PHE A 1 81  ? 111.243 97.735  142.191 1.00 139.26 ? 81  PHE A CD2   1 
ATOM   604  C CE1   . PHE A 1 81  ? 111.430 100.086 140.896 1.00 139.26 ? 81  PHE A CE1   1 
ATOM   605  C CE2   . PHE A 1 81  ? 110.385 98.010  141.182 1.00 139.26 ? 81  PHE A CE2   1 
ATOM   606  C CZ    . PHE A 1 81  ? 110.481 99.179  140.536 1.00 139.26 ? 81  PHE A CZ    1 
ATOM   607  N N     . ASP A 1 82  ? 116.508 97.905  144.402 1.00 99.54  ? 82  ASP A N     1 
ATOM   608  C CA    . ASP A 1 82  ? 117.379 97.695  145.547 1.00 99.54  ? 82  ASP A CA    1 
ATOM   609  C C     . ASP A 1 82  ? 116.887 98.460  146.772 1.00 99.54  ? 82  ASP A C     1 
ATOM   610  O O     . ASP A 1 82  ? 116.469 99.611  146.649 1.00 99.54  ? 82  ASP A O     1 
ATOM   611  C CB    . ASP A 1 82  ? 118.822 98.075  145.208 1.00 127.98 ? 82  ASP A CB    1 
ATOM   612  C CG    . ASP A 1 82  ? 119.550 96.954  144.441 1.00 127.98 ? 82  ASP A CG    1 
ATOM   613  O OD1   . ASP A 1 82  ? 118.997 95.856  144.324 1.00 127.98 ? 82  ASP A OD1   1 
ATOM   614  O OD2   . ASP A 1 82  ? 120.680 97.137  143.985 1.00 127.98 ? 82  ASP A OD2   1 
ATOM   615  N N     . PRO A 1 83  ? 117.022 97.858  147.963 1.00 96.93  ? 83  PRO A N     1 
ATOM   616  C CA    . PRO A 1 83  ? 116.495 98.372  149.242 1.00 96.93  ? 83  PRO A CA    1 
ATOM   617  C C     . PRO A 1 83  ? 116.981 99.740  149.653 1.00 96.93  ? 83  PRO A C     1 
ATOM   618  O O     . PRO A 1 83  ? 116.337 100.407 150.470 1.00 96.93  ? 83  PRO A O     1 
ATOM   619  C CB    . PRO A 1 83  ? 116.985 97.311  150.240 1.00 302.33 ? 83  PRO A CB    1 
ATOM   620  C CG    . PRO A 1 83  ? 118.137 96.642  149.560 1.00 302.33 ? 83  PRO A CG    1 
ATOM   621  C CD    . PRO A 1 83  ? 117.765 96.617  148.125 1.00 302.33 ? 83  PRO A CD    1 
ATOM   622  N N     . LYS A 1 84  ? 118.098 100.186 149.125 1.00 100.50 ? 84  LYS A N     1 
ATOM   623  C CA    . LYS A 1 84  ? 118.595 101.495 149.477 1.00 100.50 ? 84  LYS A CA    1 
ATOM   624  C C     . LYS A 1 84  ? 117.687 102.609 148.973 1.00 100.50 ? 84  LYS A C     1 
ATOM   625  O O     . LYS A 1 84  ? 117.793 103.741 149.449 1.00 100.50 ? 84  LYS A O     1 
ATOM   626  C CB    . LYS A 1 84  ? 120.007 101.653 148.925 1.00 150.62 ? 84  LYS A CB    1 
ATOM   627  C CG    . LYS A 1 84  ? 121.028 100.758 149.611 1.00 150.62 ? 84  LYS A CG    1 
ATOM   628  C CD    . LYS A 1 84  ? 122.418 100.930 149.005 1.00 150.62 ? 84  LYS A CD    1 
ATOM   629  C CE    . LYS A 1 84  ? 123.445 100.043 149.701 1.00 150.62 ? 84  LYS A CE    1 
ATOM   630  N NZ    . LYS A 1 84  ? 124.802 100.178 149.098 1.00 150.62 ? 84  LYS A NZ    1 
ATOM   631  N N     . SER A 1 85  ? 116.808 102.314 148.032 1.00 96.51  ? 85  SER A N     1 
ATOM   632  C CA    . SER A 1 85  ? 115.881 103.281 147.483 1.00 96.51  ? 85  SER A CA    1 
ATOM   633  C C     . SER A 1 85  ? 114.501 103.214 148.084 1.00 96.51  ? 85  SER A C     1 
ATOM   634  O O     . SER A 1 85  ? 113.597 103.888 147.596 1.00 96.51  ? 85  SER A O     1 
ATOM   635  C CB    . SER A 1 85  ? 115.704 103.096 145.997 1.00 129.99 ? 85  SER A CB    1 
ATOM   636  O OG    . SER A 1 85  ? 116.856 103.418 145.267 1.00 129.99 ? 85  SER A OG    1 
ATOM   637  N N     . ILE A 1 86  ? 114.276 102.424 149.090 1.00 102.05 ? 86  ILE A N     1 
ATOM   638  C CA    . ILE A 1 86  ? 112.927 102.211 149.554 1.00 102.05 ? 86  ILE A CA    1 
ATOM   639  C C     . ILE A 1 86  ? 112.650 103.084 150.800 1.00 102.05 ? 86  ILE A C     1 
ATOM   640  O O     . ILE A 1 86  ? 113.165 102.802 151.885 1.00 102.05 ? 86  ILE A O     1 
ATOM   641  C CB    . ILE A 1 86  ? 112.768 100.718 149.817 1.00 151.00 ? 86  ILE A CB    1 
ATOM   642  C CG1   . ILE A 1 86  ? 113.267 99.885  148.608 1.00 151.00 ? 86  ILE A CG1   1 
ATOM   643  C CG2   . ILE A 1 86  ? 111.403 100.370 150.132 1.00 151.00 ? 86  ILE A CG2   1 
ATOM   644  C CD1   . ILE A 1 86  ? 112.634 100.131 147.262 1.00 151.00 ? 86  ILE A CD1   1 
ATOM   645  N N     . VAL A 1 87  ? 111.790 104.108 150.692 1.00 103.11 ? 87  VAL A N     1 
ATOM   646  C CA    . VAL A 1 87  ? 111.563 105.097 151.760 1.00 103.11 ? 87  VAL A CA    1 
ATOM   647  C C     . VAL A 1 87  ? 110.100 105.207 152.193 1.00 103.11 ? 87  VAL A C     1 
ATOM   648  O O     . VAL A 1 87  ? 109.223 105.451 151.356 1.00 103.11 ? 87  VAL A O     1 
ATOM   649  C CB    . VAL A 1 87  ? 112.026 106.475 151.301 1.00 149.93 ? 87  VAL A CB    1 
ATOM   650  C CG1   . VAL A 1 87  ? 111.751 107.508 152.366 1.00 149.93 ? 87  VAL A CG1   1 
ATOM   651  C CG2   . VAL A 1 87  ? 113.472 106.425 150.944 1.00 149.93 ? 87  VAL A CG2   1 
ATOM   652  N N     . SER A 1 88  ? 109.853 105.108 153.505 1.00 109.74 ? 88  SER A N     1 
ATOM   653  C CA    . SER A 1 88  ? 108.524 105.259 154.120 1.00 109.74 ? 88  SER A CA    1 
ATOM   654  C C     . SER A 1 88  ? 108.673 105.591 155.602 1.00 109.74 ? 88  SER A C     1 
ATOM   655  O O     . SER A 1 88  ? 109.791 105.639 156.109 1.00 109.74 ? 88  SER A O     1 
ATOM   656  C CB    . SER A 1 88  ? 107.698 104.003 153.966 1.00 147.81 ? 88  SER A CB    1 
ATOM   657  O OG    . SER A 1 88  ? 108.303 102.949 154.674 1.00 147.81 ? 88  SER A OG    1 
ATOM   658  N N     . GLY A 1 89  ? 107.560 105.842 156.307 1.00 114.83 ? 89  GLY A N     1 
ATOM   659  C CA    . GLY A 1 89  ? 107.710 106.144 157.728 1.00 114.83 ? 89  GLY A CA    1 
ATOM   660  C C     . GLY A 1 89  ? 106.425 106.366 158.514 1.00 114.83 ? 89  GLY A C     1 
ATOM   661  O O     . GLY A 1 89  ? 105.316 106.377 157.973 1.00 114.83 ? 89  GLY A O     1 
ATOM   662  N N     . ALA A 1 90  ? 106.606 106.571 159.822 1.00 117.64 ? 90  ALA A N     1 
ATOM   663  C CA    . ALA A 1 90  ? 105.494 106.752 160.735 1.00 117.64 ? 90  ALA A CA    1 
ATOM   664  C C     . ALA A 1 90  ? 104.510 105.608 160.562 1.00 117.64 ? 90  ALA A C     1 
ATOM   665  O O     . ALA A 1 90  ? 104.926 104.456 160.429 1.00 117.64 ? 90  ALA A O     1 
ATOM   666  C CB    . ALA A 1 90  ? 104.824 108.105 160.507 1.00 160.42 ? 90  ALA A CB    1 
ATOM   667  N N     . ASP A 1 91  ? 103.214 105.910 160.553 1.00 117.70 ? 91  ASP A N     1 
ATOM   668  C CA    . ASP A 1 91  ? 102.169 104.915 160.388 1.00 117.70 ? 91  ASP A CA    1 
ATOM   669  C C     . ASP A 1 91  ? 101.486 105.076 159.067 1.00 117.70 ? 91  ASP A C     1 
ATOM   670  O O     . ASP A 1 91  ? 100.400 104.538 158.865 1.00 117.70 ? 91  ASP A O     1 
ATOM   671  C CB    . ASP A 1 91  ? 101.125 105.042 161.493 1.00 151.33 ? 91  ASP A CB    1 
ATOM   672  C CG    . ASP A 1 91  ? 101.687 104.814 162.883 1.00 151.33 ? 91  ASP A CG    1 
ATOM   673  O OD1   . ASP A 1 91  ? 102.439 103.859 163.090 1.00 151.33 ? 91  ASP A OD1   1 
ATOM   674  O OD2   . ASP A 1 91  ? 101.360 105.601 163.775 1.00 151.33 ? 91  ASP A OD2   1 
ATOM   675  N N     . GLY A 1 92  ? 102.075 105.840 158.173 1.00 116.95 ? 92  GLY A N     1 
ATOM   676  C CA    . GLY A 1 92  ? 101.436 106.122 156.912 1.00 116.95 ? 92  GLY A CA    1 
ATOM   677  C C     . GLY A 1 92  ? 100.410 107.218 157.068 1.00 116.95 ? 92  GLY A C     1 
ATOM   678  O O     . GLY A 1 92  ? 100.251 107.806 158.128 1.00 116.95 ? 92  GLY A O     1 
ATOM   679  N N     . ALA A 1 93  ? 99.741  107.535 155.969 1.00 117.59 ? 93  ALA A N     1 
ATOM   680  C CA    . ALA A 1 93  ? 98.728  108.576 155.928 1.00 117.59 ? 93  ALA A CA    1 
ATOM   681  C C     . ALA A 1 93  ? 97.949  108.409 154.641 1.00 117.59 ? 93  ALA A C     1 
ATOM   682  O O     . ALA A 1 93  ? 98.454  107.791 153.711 1.00 117.59 ? 93  ALA A O     1 
ATOM   683  C CB    . ALA A 1 93  ? 99.354  109.956 155.968 1.00 160.35 ? 93  ALA A CB    1 
ATOM   684  N N     . GLY A 1 94  ? 96.746  108.977 154.549 1.00 112.82 ? 94  GLY A N     1 
ATOM   685  C CA    . GLY A 1 94  ? 96.055  108.837 153.272 1.00 112.82 ? 94  GLY A CA    1 
ATOM   686  C C     . GLY A 1 94  ? 94.702  109.510 153.120 1.00 112.82 ? 94  GLY A C     1 
ATOM   687  O O     . GLY A 1 94  ? 94.150  110.092 154.048 1.00 112.82 ? 94  GLY A O     1 
ATOM   688  N N     . ASN A 1 95  ? 94.231  109.460 151.872 1.00 120.13 ? 95  ASN A N     1 
ATOM   689  C CA    . ASN A 1 95  ? 92.987  110.013 151.348 1.00 120.13 ? 95  ASN A CA    1 
ATOM   690  C C     . ASN A 1 95  ? 92.786  111.486 151.644 1.00 120.13 ? 95  ASN A C     1 
ATOM   691  O O     . ASN A 1 95  ? 91.665  111.920 151.907 1.00 120.13 ? 95  ASN A O     1 
ATOM   692  C CB    . ASN A 1 95  ? 91.779  109.232 151.842 1.00 162.74 ? 95  ASN A CB    1 
ATOM   693  C CG    . ASN A 1 95  ? 90.553  109.459 150.969 1.00 162.74 ? 95  ASN A CG    1 
ATOM   694  O OD1   . ASN A 1 95  ? 90.674  109.595 149.750 1.00 162.74 ? 95  ASN A OD1   1 
ATOM   695  N ND2   . ASN A 1 95  ? 89.379  109.515 151.585 1.00 162.74 ? 95  ASN A ND2   1 
ATOM   696  N N     . ASN A 1 96  ? 93.852  112.272 151.603 1.00 117.73 ? 96  ASN A N     1 
ATOM   697  C CA    . ASN A 1 96  ? 93.748  113.712 151.837 1.00 117.73 ? 96  ASN A CA    1 
ATOM   698  C C     . ASN A 1 96  ? 95.015  114.413 151.401 1.00 117.73 ? 96  ASN A C     1 
ATOM   699  O O     . ASN A 1 96  ? 96.061  114.258 152.037 1.00 117.73 ? 96  ASN A O     1 
ATOM   700  C CB    . ASN A 1 96  ? 93.497  114.021 153.302 1.00 159.49 ? 96  ASN A CB    1 
ATOM   701  C CG    . ASN A 1 96  ? 93.226  115.494 153.575 1.00 159.49 ? 96  ASN A CG    1 
ATOM   702  O OD1   . ASN A 1 96  ? 93.560  116.402 152.798 1.00 159.49 ? 96  ASN A OD1   1 
ATOM   703  N ND2   . ASN A 1 96  ? 92.614  115.738 154.723 1.00 159.49 ? 96  ASN A ND2   1 
ATOM   704  N N     . PHE A 1 97  ? 94.917  115.227 150.358 1.00 114.65 ? 97  PHE A N     1 
ATOM   705  C CA    . PHE A 1 97  ? 96.078  115.942 149.857 1.00 114.65 ? 97  PHE A CA    1 
ATOM   706  C C     . PHE A 1 97  ? 96.769  116.666 150.969 1.00 114.65 ? 97  PHE A C     1 
ATOM   707  O O     . PHE A 1 97  ? 97.995  116.692 151.042 1.00 114.65 ? 97  PHE A O     1 
ATOM   708  C CB    . PHE A 1 97  ? 95.662  116.976 148.824 1.00 159.92 ? 97  PHE A CB    1 
ATOM   709  C CG    . PHE A 1 97  ? 96.775  117.841 148.357 1.00 159.92 ? 97  PHE A CG    1 
ATOM   710  C CD1   . PHE A 1 97  ? 97.084  119.026 148.998 1.00 159.92 ? 97  PHE A CD1   1 
ATOM   711  C CD2   . PHE A 1 97  ? 97.503  117.472 147.268 1.00 159.92 ? 97  PHE A CD2   1 
ATOM   712  C CE1   . PHE A 1 97  ? 98.111  119.808 148.558 1.00 159.92 ? 97  PHE A CE1   1 
ATOM   713  C CE2   . PHE A 1 97  ? 98.523  118.257 146.819 1.00 159.92 ? 97  PHE A CE2   1 
ATOM   714  C CZ    . PHE A 1 97  ? 98.830  119.423 147.465 1.00 159.92 ? 97  PHE A CZ    1 
ATOM   715  N N     . ALA A 1 98  ? 95.988  117.318 151.806 1.00 118.56 ? 98  ALA A N     1 
ATOM   716  C CA    . ALA A 1 98  ? 96.555  118.173 152.822 1.00 118.56 ? 98  ALA A CA    1 
ATOM   717  C C     . ALA A 1 98  ? 97.401  117.384 153.784 1.00 118.56 ? 98  ALA A C     1 
ATOM   718  O O     . ALA A 1 98  ? 98.395  117.906 154.301 1.00 118.56 ? 98  ALA A O     1 
ATOM   719  C CB    . ALA A 1 98  ? 95.448  118.902 153.571 1.00 161.67 ? 98  ALA A CB    1 
ATOM   720  N N     . ILE A 1 99  ? 97.013  116.142 154.054 1.00 116.97 ? 99  ILE A N     1 
ATOM   721  C CA    . ILE A 1 99  ? 97.776  115.337 154.985 1.00 116.97 ? 99  ILE A CA    1 
ATOM   722  C C     . ILE A 1 99  ? 99.052  114.896 154.340 1.00 116.97 ? 99  ILE A C     1 
ATOM   723  O O     . ILE A 1 99  ? 100.130 115.016 154.917 1.00 116.97 ? 99  ILE A O     1 
ATOM   724  C CB    . ILE A 1 99  ? 96.974  114.128 155.466 1.00 173.07 ? 99  ILE A CB    1 
ATOM   725  C CG1   . ILE A 1 99  ? 95.704  114.563 156.211 1.00 173.07 ? 99  ILE A CG1   1 
ATOM   726  C CG2   . ILE A 1 99  ? 97.823  113.253 156.341 1.00 173.07 ? 99  ILE A CG2   1 
ATOM   727  C CD1   . ILE A 1 99  ? 95.915  115.349 157.496 1.00 173.07 ? 99  ILE A CD1   1 
ATOM   728  N N     . GLY A 1 100 ? 98.975  114.401 153.125 1.00 117.03 ? 100 GLY A N     1 
ATOM   729  C CA    . GLY A 1 100 ? 100.207 113.989 152.490 1.00 117.03 ? 100 GLY A CA    1 
ATOM   730  C C     . GLY A 1 100 ? 101.166 115.155 152.342 1.00 117.03 ? 100 GLY A C     1 
ATOM   731  O O     . GLY A 1 100 ? 102.362 115.037 152.622 1.00 117.03 ? 100 GLY A O     1 
ATOM   732  N N     . PHE A 1 101 ? 100.630 116.316 151.978 1.00 113.22 ? 101 PHE A N     1 
ATOM   733  C CA    . PHE A 1 101 ? 101.444 117.488 151.709 1.00 113.22 ? 101 PHE A CA    1 
ATOM   734  C C     . PHE A 1 101 ? 102.064 118.074 152.963 1.00 113.22 ? 101 PHE A C     1 
ATOM   735  O O     . PHE A 1 101 ? 103.230 118.459 152.928 1.00 113.22 ? 101 PHE A O     1 
ATOM   736  C CB    . PHE A 1 101 ? 100.636 118.568 151.013 1.00 157.92 ? 101 PHE A CB    1 
ATOM   737  C CG    . PHE A 1 101 ? 101.491 119.612 150.402 1.00 157.92 ? 101 PHE A CG    1 
ATOM   738  C CD1   . PHE A 1 101 ? 101.936 119.457 149.114 1.00 157.92 ? 101 PHE A CD1   1 
ATOM   739  C CD2   . PHE A 1 101 ? 101.907 120.708 151.105 1.00 157.92 ? 101 PHE A CD2   1 
ATOM   740  C CE1   . PHE A 1 101 ? 102.752 120.388 148.534 1.00 157.92 ? 101 PHE A CE1   1 
ATOM   741  C CE2   . PHE A 1 101 ? 102.723 121.637 150.528 1.00 157.92 ? 101 PHE A CE2   1 
ATOM   742  C CZ    . PHE A 1 101 ? 103.145 121.478 149.242 1.00 157.92 ? 101 PHE A CZ    1 
ATOM   743  N N     . ASN A 1 102 ? 101.313 118.202 154.071 1.00 121.62 ? 102 ASN A N     1 
ATOM   744  C CA    . ASN A 1 102 ? 101.896 118.805 155.278 1.00 121.62 ? 102 ASN A CA    1 
ATOM   745  C C     . ASN A 1 102 ? 102.226 117.858 156.451 1.00 121.62 ? 102 ASN A C     1 
ATOM   746  O O     . ASN A 1 102 ? 103.000 118.264 157.328 1.00 121.62 ? 102 ASN A O     1 
ATOM   747  C CB    . ASN A 1 102 ? 100.994 119.894 155.847 1.00 164.76 ? 102 ASN A CB    1 
ATOM   748  C CG    . ASN A 1 102 ? 100.966 121.143 155.038 1.00 164.76 ? 102 ASN A CG    1 
ATOM   749  O OD1   . ASN A 1 102 ? 101.921 121.530 154.377 1.00 164.76 ? 102 ASN A OD1   1 
ATOM   750  N ND2   . ASN A 1 102 ? 99.851  121.828 155.130 1.00 164.76 ? 102 ASN A ND2   1 
ATOM   751  N N     . GLU A 1 103 ? 101.674 116.641 156.532 1.00 122.80 ? 103 GLU A N     1 
ATOM   752  C CA    . GLU A 1 103 ? 101.860 115.791 157.707 1.00 122.80 ? 103 GLU A CA    1 
ATOM   753  C C     . GLU A 1 103 ? 102.735 114.567 157.451 1.00 122.80 ? 103 GLU A C     1 
ATOM   754  O O     . GLU A 1 103 ? 102.728 113.622 158.243 1.00 122.80 ? 103 GLU A O     1 
ATOM   755  C CB    . GLU A 1 103 ? 100.507 115.340 158.244 1.00 164.94 ? 103 GLU A CB    1 
ATOM   756  C CG    . GLU A 1 103 ? 99.565  116.452 158.640 1.00 164.94 ? 103 GLU A CG    1 
ATOM   757  C CD    . GLU A 1 103 ? 100.047 117.246 159.808 1.00 164.94 ? 103 GLU A CD    1 
ATOM   758  O OE1   . GLU A 1 103 ? 100.659 116.669 160.701 1.00 164.94 ? 103 GLU A OE1   1 
ATOM   759  O OE2   . GLU A 1 103 ? 99.812  118.449 159.837 1.00 164.94 ? 103 GLU A OE2   1 
ATOM   760  N N     . HIS A 1 104 ? 103.487 114.571 156.366 1.00 122.22 ? 104 HIS A N     1 
ATOM   761  C CA    . HIS A 1 104 ? 104.305 113.430 156.000 1.00 122.22 ? 104 HIS A CA    1 
ATOM   762  C C     . HIS A 1 104 ? 105.425 113.165 156.990 1.00 122.22 ? 104 HIS A C     1 
ATOM   763  O O     . HIS A 1 104 ? 105.878 112.019 157.107 1.00 122.22 ? 104 HIS A O     1 
ATOM   764  C CB    . HIS A 1 104 ? 104.902 113.674 154.634 1.00 166.19 ? 104 HIS A CB    1 
ATOM   765  C CG    . HIS A 1 104 ? 105.503 115.016 154.547 1.00 166.19 ? 104 HIS A CG    1 
ATOM   766  N ND1   . HIS A 1 104 ? 104.743 116.115 154.277 1.00 166.19 ? 104 HIS A ND1   1 
ATOM   767  C CD2   . HIS A 1 104 ? 106.760 115.461 154.755 1.00 166.19 ? 104 HIS A CD2   1 
ATOM   768  C CE1   . HIS A 1 104 ? 105.502 117.189 154.311 1.00 166.19 ? 104 HIS A CE1   1 
ATOM   769  N NE2   . HIS A 1 104 ? 106.733 116.824 154.600 1.00 166.19 ? 104 HIS A NE2   1 
ATOM   770  N N     . GLY A 1 105 ? 105.883 114.192 157.697 1.00 118.16 ? 105 GLY A N     1 
ATOM   771  C CA    . GLY A 1 105 ? 106.977 114.073 158.649 1.00 118.16 ? 105 GLY A CA    1 
ATOM   772  C C     . GLY A 1 105 ? 108.244 114.713 158.114 1.00 118.16 ? 105 GLY A C     1 
ATOM   773  O O     . GLY A 1 105 ? 108.699 114.365 157.020 1.00 118.16 ? 105 GLY A O     1 
ATOM   774  N N     . ALA A 1 106 ? 108.859 115.610 158.885 1.00 108.69 ? 106 ALA A N     1 
ATOM   775  C CA    . ALA A 1 106 ? 110.033 116.285 158.366 1.00 108.69 ? 106 ALA A CA    1 
ATOM   776  C C     . ALA A 1 106 ? 111.088 115.286 157.977 1.00 108.69 ? 106 ALA A C     1 
ATOM   777  O O     . ALA A 1 106 ? 111.792 115.447 156.968 1.00 108.69 ? 106 ALA A O     1 
ATOM   778  C CB    . ALA A 1 106 ? 110.584 117.223 159.415 1.00 148.21 ? 106 ALA A CB    1 
ATOM   779  N N     . GLU A 1 107 ? 111.193 114.237 158.772 1.00 103.70 ? 107 GLU A N     1 
ATOM   780  C CA    . GLU A 1 107 ? 112.173 113.198 158.551 1.00 103.70 ? 107 GLU A CA    1 
ATOM   781  C C     . GLU A 1 107 ? 111.855 112.404 157.302 1.00 103.70 ? 107 GLU A C     1 
ATOM   782  O O     . GLU A 1 107 ? 112.766 111.961 156.596 1.00 103.70 ? 107 GLU A O     1 
ATOM   783  C CB    . GLU A 1 107 ? 112.201 112.301 159.769 1.00 139.28 ? 107 GLU A CB    1 
ATOM   784  C CG    . GLU A 1 107 ? 112.650 113.018 161.003 1.00 139.28 ? 107 GLU A CG    1 
ATOM   785  C CD    . GLU A 1 107 ? 111.559 113.867 161.650 1.00 139.28 ? 107 GLU A CD    1 
ATOM   786  O OE1   . GLU A 1 107 ? 110.405 113.830 161.191 1.00 139.28 ? 107 GLU A OE1   1 
ATOM   787  O OE2   . GLU A 1 107 ? 111.872 114.589 162.600 1.00 139.28 ? 107 GLU A OE2   1 
ATOM   788  N N     . THR A 1 108 ? 110.569 112.206 157.035 1.00 102.94 ? 108 THR A N     1 
ATOM   789  C CA    . THR A 1 108 ? 110.158 111.424 155.887 1.00 102.94 ? 108 THR A CA    1 
ATOM   790  C C     . THR A 1 108 ? 110.593 112.089 154.608 1.00 102.94 ? 108 THR A C     1 
ATOM   791  O O     . THR A 1 108 ? 111.141 111.439 153.701 1.00 102.94 ? 108 THR A O     1 
ATOM   792  C CB    . THR A 1 108 ? 108.655 111.276 155.854 1.00 144.10 ? 108 THR A CB    1 
ATOM   793  O OG1   . THR A 1 108 ? 108.184 110.677 157.067 1.00 144.10 ? 108 THR A OG1   1 
ATOM   794  C CG2   . THR A 1 108 ? 108.264 110.416 154.700 1.00 144.10 ? 108 THR A CG2   1 
ATOM   795  N N     . LEU A 1 109 ? 110.382 113.401 154.514 1.00 103.75 ? 109 LEU A N     1 
ATOM   796  C CA    . LEU A 1 109 ? 110.770 114.078 153.284 1.00 103.75 ? 109 LEU A CA    1 
ATOM   797  C C     . LEU A 1 109 ? 112.261 114.157 153.163 1.00 103.75 ? 109 LEU A C     1 
ATOM   798  O O     . LEU A 1 109 ? 112.794 114.050 152.054 1.00 103.75 ? 109 LEU A O     1 
ATOM   799  C CB    . LEU A 1 109 ? 110.219 115.481 153.161 1.00 153.51 ? 109 LEU A CB    1 
ATOM   800  C CG    . LEU A 1 109 ? 110.535 116.172 151.837 1.00 153.51 ? 109 LEU A CG    1 
ATOM   801  C CD1   . LEU A 1 109 ? 109.998 115.420 150.622 1.00 153.51 ? 109 LEU A CD1   1 
ATOM   802  C CD2   . LEU A 1 109 ? 109.939 117.485 151.856 1.00 153.51 ? 109 LEU A CD2   1 
ATOM   803  N N     . GLU A 1 110 ? 112.951 114.362 154.267 1.00 103.00 ? 110 GLU A N     1 
ATOM   804  C CA    . GLU A 1 110 ? 114.386 114.414 154.152 1.00 103.00 ? 110 GLU A CA    1 
ATOM   805  C C     . GLU A 1 110 ? 114.914 113.097 153.646 1.00 103.00 ? 110 GLU A C     1 
ATOM   806  O O     . GLU A 1 110 ? 115.814 113.074 152.816 1.00 103.00 ? 110 GLU A O     1 
ATOM   807  C CB    . GLU A 1 110 ? 115.005 114.788 155.480 1.00 138.34 ? 110 GLU A CB    1 
ATOM   808  C CG    . GLU A 1 110 ? 116.477 115.059 155.433 1.00 138.34 ? 110 GLU A CG    1 
ATOM   809  C CD    . GLU A 1 110 ? 116.833 116.284 154.634 1.00 138.34 ? 110 GLU A CD    1 
ATOM   810  O OE1   . GLU A 1 110 ? 115.967 117.126 154.402 1.00 138.34 ? 110 GLU A OE1   1 
ATOM   811  O OE2   . GLU A 1 110 ? 117.992 116.404 154.236 1.00 138.34 ? 110 GLU A OE2   1 
ATOM   812  N N     . LYS A 1 111 ? 114.373 111.987 154.115 1.00 97.93  ? 111 LYS A N     1 
ATOM   813  C CA    . LYS A 1 111 ? 114.862 110.717 153.616 1.00 97.93  ? 111 LYS A CA    1 
ATOM   814  C C     . LYS A 1 111 ? 114.628 110.599 152.133 1.00 97.93  ? 111 LYS A C     1 
ATOM   815  O O     . LYS A 1 111 ? 115.497 110.099 151.408 1.00 97.93  ? 111 LYS A O     1 
ATOM   816  C CB    . LYS A 1 111 ? 114.222 109.549 154.343 1.00 146.76 ? 111 LYS A CB    1 
ATOM   817  C CG    . LYS A 1 111 ? 114.713 109.345 155.742 1.00 146.76 ? 111 LYS A CG    1 
ATOM   818  C CD    . LYS A 1 111 ? 114.032 108.168 156.403 1.00 146.76 ? 111 LYS A CD    1 
ATOM   819  C CE    . LYS A 1 111 ? 114.502 107.986 157.831 1.00 146.76 ? 111 LYS A CE    1 
ATOM   820  N NZ    . LYS A 1 111 ? 113.843 106.825 158.500 1.00 146.76 ? 111 LYS A NZ    1 
ATOM   821  N N     . VAL A 1 112 ? 113.484 111.070 151.648 1.00 97.67  ? 112 VAL A N     1 
ATOM   822  C CA    . VAL A 1 112 ? 113.270 110.992 150.212 1.00 97.67  ? 112 VAL A CA    1 
ATOM   823  C C     . VAL A 1 112 ? 114.321 111.785 149.499 1.00 97.67  ? 112 VAL A C     1 
ATOM   824  O O     . VAL A 1 112 ? 114.904 111.316 148.517 1.00 97.67  ? 112 VAL A O     1 
ATOM   825  C CB    . VAL A 1 112 ? 111.896 111.498 149.790 1.00 142.02 ? 112 VAL A CB    1 
ATOM   826  C CG1   . VAL A 1 112 ? 111.803 111.575 148.275 1.00 142.02 ? 112 VAL A CG1   1 
ATOM   827  C CG2   . VAL A 1 112 ? 110.846 110.590 150.317 1.00 142.02 ? 112 VAL A CG2   1 
ATOM   828  N N     . MET A 1 113 ? 114.591 112.985 149.972 1.00 97.01  ? 113 MET A N     1 
ATOM   829  C CA    . MET A 1 113 ? 115.563 113.810 149.289 1.00 97.01  ? 113 MET A CA    1 
ATOM   830  C C     . MET A 1 113 ? 116.971 113.278 149.409 1.00 97.01  ? 113 MET A C     1 
ATOM   831  O O     . MET A 1 113 ? 117.763 113.465 148.493 1.00 97.01  ? 113 MET A O     1 
ATOM   832  C CB    . MET A 1 113 ? 115.503 115.225 149.789 1.00 139.32 ? 113 MET A CB    1 
ATOM   833  C CG    . MET A 1 113 ? 114.251 115.887 149.398 1.00 139.32 ? 113 MET A CG    1 
ATOM   834  S SD    . MET A 1 113 ? 114.103 116.001 147.657 1.00 139.32 ? 113 MET A SD    1 
ATOM   835  C CE    . MET A 1 113 ? 112.352 115.710 147.537 1.00 139.32 ? 113 MET A CE    1 
ATOM   836  N N     . GLN A 1 114 ? 117.318 112.640 150.500 1.00 94.59  ? 114 GLN A N     1 
ATOM   837  C CA    . GLN A 1 114 ? 118.650 112.088 150.581 1.00 94.59  ? 114 GLN A CA    1 
ATOM   838  C C     . GLN A 1 114 ? 118.810 111.008 149.549 1.00 94.59  ? 114 GLN A C     1 
ATOM   839  O O     . GLN A 1 114 ? 119.863 110.901 148.921 1.00 94.59  ? 114 GLN A O     1 
ATOM   840  C CB    . GLN A 1 114 ? 118.926 111.547 151.964 1.00 132.13 ? 114 GLN A CB    1 
ATOM   841  C CG    . GLN A 1 114 ? 120.291 111.044 152.161 1.00 132.13 ? 114 GLN A CG    1 
ATOM   842  C CD    . GLN A 1 114 ? 121.306 112.120 152.036 1.00 132.13 ? 114 GLN A CD    1 
ATOM   843  O OE1   . GLN A 1 114 ? 121.211 113.163 152.676 1.00 132.13 ? 114 GLN A OE1   1 
ATOM   844  N NE2   . GLN A 1 114 ? 122.306 111.888 151.200 1.00 132.13 ? 114 GLN A NE2   1 
ATOM   845  N N     . VAL A 1 115 ? 117.772 110.210 149.339 1.00 92.70  ? 115 VAL A N     1 
ATOM   846  C CA    . VAL A 1 115 ? 117.871 109.188 148.319 1.00 92.70  ? 115 VAL A CA    1 
ATOM   847  C C     . VAL A 1 115 ? 117.941 109.816 146.952 1.00 92.70  ? 115 VAL A C     1 
ATOM   848  O O     . VAL A 1 115 ? 118.686 109.337 146.093 1.00 92.70  ? 115 VAL A O     1 
ATOM   849  C CB    . VAL A 1 115 ? 116.725 108.189 148.408 1.00 134.79 ? 115 VAL A CB    1 
ATOM   850  C CG1   . VAL A 1 115 ? 116.766 107.256 147.251 1.00 134.79 ? 115 VAL A CG1   1 
ATOM   851  C CG2   . VAL A 1 115 ? 116.854 107.427 149.654 1.00 134.79 ? 115 VAL A CG2   1 
ATOM   852  N N     . VAL A 1 116 ? 117.161 110.860 146.702 1.00 90.90  ? 116 VAL A N     1 
ATOM   853  C CA    . VAL A 1 116 ? 117.237 111.491 145.394 1.00 90.90  ? 116 VAL A CA    1 
ATOM   854  C C     . VAL A 1 116 ? 118.622 112.004 145.147 1.00 90.90  ? 116 VAL A C     1 
ATOM   855  O O     . VAL A 1 116 ? 119.172 111.815 144.061 1.00 90.90  ? 116 VAL A O     1 
ATOM   856  C CB    . VAL A 1 116 ? 116.230 112.623 145.223 1.00 132.17 ? 116 VAL A CB    1 
ATOM   857  C CG1   . VAL A 1 116 ? 116.506 113.365 143.916 1.00 132.17 ? 116 VAL A CG1   1 
ATOM   858  C CG2   . VAL A 1 116 ? 114.817 112.072 145.220 1.00 132.17 ? 116 VAL A CG2   1 
ATOM   859  N N     . GLU A 1 117 ? 119.218 112.656 146.130 1.00 93.03  ? 117 GLU A N     1 
ATOM   860  C CA    . GLU A 1 117 ? 120.561 113.169 145.946 1.00 93.03  ? 117 GLU A CA    1 
ATOM   861  C C     . GLU A 1 117 ? 121.554 112.062 145.709 1.00 93.03  ? 117 GLU A C     1 
ATOM   862  O O     . GLU A 1 117 ? 122.482 112.232 144.933 1.00 93.03  ? 117 GLU A O     1 
ATOM   863  C CB    . GLU A 1 117 ? 121.001 113.995 147.140 1.00 124.95 ? 117 GLU A CB    1 
ATOM   864  C CG    . GLU A 1 117 ? 122.430 114.543 147.042 1.00 124.95 ? 117 GLU A CG    1 
ATOM   865  C CD    . GLU A 1 117 ? 122.647 115.528 145.906 1.00 124.95 ? 117 GLU A CD    1 
ATOM   866  O OE1   . GLU A 1 117 ? 121.672 116.054 145.363 1.00 124.95 ? 117 GLU A OE1   1 
ATOM   867  O OE2   . GLU A 1 117 ? 123.804 115.783 145.565 1.00 124.95 ? 117 GLU A OE2   1 
ATOM   868  N N     . GLN A 1 118 ? 121.408 110.936 146.382 1.00 87.83  ? 118 GLN A N     1 
ATOM   869  C CA    . GLN A 1 118 ? 122.323 109.839 146.133 1.00 87.83  ? 118 GLN A CA    1 
ATOM   870  C C     . GLN A 1 118 ? 122.199 109.346 144.718 1.00 87.83  ? 118 GLN A C     1 
ATOM   871  O O     . GLN A 1 118 ? 123.202 109.137 144.048 1.00 87.83  ? 118 GLN A O     1 
ATOM   872  C CB    . GLN A 1 118 ? 122.058 108.719 147.107 1.00 122.69 ? 118 GLN A CB    1 
ATOM   873  C CG    . GLN A 1 118 ? 122.977 107.560 147.012 1.00 122.69 ? 118 GLN A CG    1 
ATOM   874  C CD    . GLN A 1 118 ? 124.370 107.906 147.365 1.00 122.69 ? 118 GLN A CD    1 
ATOM   875  O OE1   . GLN A 1 118 ? 124.609 108.698 148.272 1.00 122.69 ? 118 GLN A OE1   1 
ATOM   876  N NE2   . GLN A 1 118 ? 125.325 107.299 146.660 1.00 122.69 ? 118 GLN A NE2   1 
ATOM   877  N N     . ARG A 1 119 ? 120.986 109.218 144.202 1.00 88.48  ? 119 ARG A N     1 
ATOM   878  C CA    . ARG A 1 119 ? 120.889 108.773 142.821 1.00 88.48  ? 119 ARG A CA    1 
ATOM   879  C C     . ARG A 1 119 ? 121.507 109.789 141.883 1.00 88.48  ? 119 ARG A C     1 
ATOM   880  O O     . ARG A 1 119 ? 122.091 109.424 140.862 1.00 88.48  ? 119 ARG A O     1 
ATOM   881  C CB    . ARG A 1 119 ? 119.452 108.521 142.407 1.00 129.90 ? 119 ARG A CB    1 
ATOM   882  C CG    . ARG A 1 119 ? 118.740 107.413 143.130 1.00 129.90 ? 119 ARG A CG    1 
ATOM   883  C CD    . ARG A 1 119 ? 119.212 106.041 142.756 1.00 129.90 ? 119 ARG A CD    1 
ATOM   884  N NE    . ARG A 1 119 ? 120.348 105.605 143.536 1.00 129.90 ? 119 ARG A NE    1 
ATOM   885  C CZ    . ARG A 1 119 ? 120.265 105.182 144.784 1.00 129.90 ? 119 ARG A CZ    1 
ATOM   886  N NH1   . ARG A 1 119 ? 119.117 105.133 145.402 1.00 129.90 ? 119 ARG A NH1   1 
ATOM   887  N NH2   . ARG A 1 119 ? 121.370 104.801 145.427 1.00 129.90 ? 119 ARG A NH2   1 
ATOM   888  N N     . VAL A 1 120 ? 121.391 111.059 142.221 1.00 86.53  ? 120 VAL A N     1 
ATOM   889  C CA    . VAL A 1 120 ? 121.974 112.107 141.415 1.00 86.53  ? 120 VAL A CA    1 
ATOM   890  C C     . VAL A 1 120 ? 123.485 112.095 141.469 1.00 86.53  ? 120 VAL A C     1 
ATOM   891  O O     . VAL A 1 120 ? 124.131 112.237 140.443 1.00 86.53  ? 120 VAL A O     1 
ATOM   892  C CB    . VAL A 1 120 ? 121.405 113.457 141.843 1.00 125.82 ? 120 VAL A CB    1 
ATOM   893  C CG1   . VAL A 1 120 ? 122.177 114.593 141.233 1.00 125.82 ? 120 VAL A CG1   1 
ATOM   894  C CG2   . VAL A 1 120 ? 119.954 113.547 141.425 1.00 125.82 ? 120 VAL A CG2   1 
ATOM   895  N N     . SER A 1 121 ? 124.089 111.948 142.631 1.00 85.19  ? 121 SER A N     1 
ATOM   896  C CA    . SER A 1 121 ? 125.542 112.021 142.696 1.00 85.19  ? 121 SER A CA    1 
ATOM   897  C C     . SER A 1 121 ? 126.201 110.864 141.987 1.00 85.19  ? 121 SER A C     1 
ATOM   898  O O     . SER A 1 121 ? 127.327 110.997 141.521 1.00 85.19  ? 121 SER A O     1 
ATOM   899  C CB    . SER A 1 121 ? 126.015 112.066 144.136 1.00 114.74 ? 121 SER A CB    1 
ATOM   900  O OG    . SER A 1 121 ? 125.859 110.812 144.761 1.00 114.74 ? 121 SER A OG    1 
ATOM   901  N N     . GLU A 1 122 ? 125.508 109.758 141.846 1.00 88.82  ? 122 GLU A N     1 
ATOM   902  C CA    . GLU A 1 122 ? 126.002 108.580 141.154 1.00 88.82  ? 122 GLU A CA    1 
ATOM   903  C C     . GLU A 1 122 ? 125.926 108.719 139.653 1.00 88.82  ? 122 GLU A C     1 
ATOM   904  O O     . GLU A 1 122 ? 126.379 107.833 138.930 1.00 88.82  ? 122 GLU A O     1 
ATOM   905  C CB    . GLU A 1 122 ? 125.173 107.360 141.544 1.00 119.30 ? 122 GLU A CB    1 
ATOM   906  C CG    . GLU A 1 122 ? 125.291 106.912 142.976 1.00 119.30 ? 122 GLU A CG    1 
ATOM   907  C CD    . GLU A 1 122 ? 124.266 105.850 143.339 1.00 119.30 ? 122 GLU A CD    1 
ATOM   908  O OE1   . GLU A 1 122 ? 123.433 105.498 142.491 1.00 119.30 ? 122 GLU A OE1   1 
ATOM   909  O OE2   . GLU A 1 122 ? 124.284 105.385 144.482 1.00 119.30 ? 122 GLU A OE2   1 
ATOM   910  N N     . THR A 1 123 ? 125.322 109.779 139.185 1.00 89.99  ? 123 THR A N     1 
ATOM   911  C CA    . THR A 1 123 ? 125.012 109.993 137.790 1.00 89.99  ? 123 THR A CA    1 
ATOM   912  C C     . THR A 1 123 ? 125.950 111.041 137.166 1.00 89.99  ? 123 THR A C     1 
ATOM   913  O O     . THR A 1 123 ? 126.229 112.068 137.777 1.00 89.99  ? 123 THR A O     1 
ATOM   914  C CB    . THR A 1 123 ? 123.540 110.398 137.737 1.00 125.97 ? 123 THR A CB    1 
ATOM   915  O OG1   . THR A 1 123 ? 122.732 109.340 138.287 1.00 125.97 ? 123 THR A OG1   1 
ATOM   916  C CG2   . THR A 1 123 ? 123.123 110.570 136.408 1.00 125.97 ? 123 THR A CG2   1 
ATOM   917  N N     . GLU A 1 124 ? 126.465 110.780 135.959 1.00 87.66  ? 124 GLU A N     1 
ATOM   918  C CA    . GLU A 1 124 ? 127.421 111.705 135.333 1.00 87.66  ? 124 GLU A CA    1 
ATOM   919  C C     . GLU A 1 124 ? 126.823 113.070 135.098 1.00 87.66  ? 124 GLU A C     1 
ATOM   920  O O     . GLU A 1 124 ? 127.472 114.084 135.343 1.00 87.66  ? 124 GLU A O     1 
ATOM   921  C CB    . GLU A 1 124 ? 127.929 111.152 134.001 1.00 117.74 ? 124 GLU A CB    1 
ATOM   922  C CG    . GLU A 1 124 ? 128.929 112.051 133.279 1.00 117.74 ? 124 GLU A CG    1 
ATOM   923  C CD    . GLU A 1 124 ? 129.510 111.465 131.987 1.00 117.74 ? 124 GLU A CD    1 
ATOM   924  O OE1   . GLU A 1 124 ? 128.779 110.880 131.171 1.00 117.74 ? 124 GLU A OE1   1 
ATOM   925  O OE2   . GLU A 1 124 ? 130.722 111.609 131.791 1.00 117.74 ? 124 GLU A OE2   1 
ATOM   926  N N     . SER A 1 125 ? 125.606 113.119 134.583 1.00 87.16  ? 125 SER A N     1 
ATOM   927  C CA    . SER A 1 125 ? 124.936 114.398 134.356 1.00 87.16  ? 125 SER A CA    1 
ATOM   928  C C     . SER A 1 125 ? 123.430 114.223 134.208 1.00 87.16  ? 125 SER A C     1 
ATOM   929  O O     . SER A 1 125 ? 122.966 113.521 133.305 1.00 87.16  ? 125 SER A O     1 
ATOM   930  C CB    . SER A 1 125 ? 125.501 115.064 133.165 1.00 117.40 ? 125 SER A CB    1 
ATOM   931  O OG    . SER A 1 125 ? 124.819 116.258 132.916 1.00 117.40 ? 125 SER A OG    1 
ATOM   932  N N     . ILE A 1 126 ? 122.667 114.919 135.048 1.00 77.72  ? 126 ILE A N     1 
ATOM   933  C CA    . ILE A 1 126 ? 121.228 114.749 135.092 1.00 77.72  ? 126 ILE A CA    1 
ATOM   934  C C     . ILE A 1 126 ? 120.579 115.380 133.895 1.00 77.72  ? 126 ILE A C     1 
ATOM   935  O O     . ILE A 1 126 ? 120.738 116.571 133.651 1.00 77.72  ? 126 ILE A O     1 
ATOM   936  C CB    . ILE A 1 126 ? 120.680 115.399 136.348 1.00 115.00 ? 126 ILE A CB    1 
ATOM   937  C CG1   . ILE A 1 126 ? 121.297 114.767 137.547 1.00 115.00 ? 126 ILE A CG1   1 
ATOM   938  C CG2   . ILE A 1 126 ? 119.186 115.282 136.408 1.00 115.00 ? 126 ILE A CG2   1 
ATOM   939  C CD1   . ILE A 1 126 ? 121.083 113.302 137.677 1.00 115.00 ? 126 ILE A CD1   1 
ATOM   940  N N     . GLY A 1 127 ? 119.810 114.601 133.173 1.00 78.67  ? 127 GLY A N     1 
ATOM   941  C CA    . GLY A 1 127 ? 119.093 115.092 132.025 1.00 78.67  ? 127 GLY A CA    1 
ATOM   942  C C     . GLY A 1 127 ? 117.689 115.403 132.379 1.00 78.67  ? 127 GLY A C     1 
ATOM   943  O O     . GLY A 1 127 ? 116.935 115.904 131.544 1.00 78.67  ? 127 GLY A O     1 
ATOM   944  N N     . GLY A 1 128 ? 117.315 115.110 133.608 1.00 82.42  ? 128 GLY A N     1 
ATOM   945  C CA    . GLY A 1 128 ? 115.975 115.329 134.055 1.00 82.42  ? 128 GLY A CA    1 
ATOM   946  C C     . GLY A 1 128 ? 115.495 114.301 135.036 1.00 82.42  ? 128 GLY A C     1 
ATOM   947  O O     . GLY A 1 128 ? 116.159 113.294 135.282 1.00 82.42  ? 128 GLY A O     1 
ATOM   948  N N     . PHE A 1 129 ? 114.327 114.561 135.600 1.00 81.97  ? 129 PHE A N     1 
ATOM   949  C CA    . PHE A 1 129 ? 113.674 113.689 136.544 1.00 81.97  ? 129 PHE A CA    1 
ATOM   950  C C     . PHE A 1 129 ? 112.346 113.263 135.981 1.00 81.97  ? 129 PHE A C     1 
ATOM   951  O O     . PHE A 1 129 ? 111.703 114.028 135.275 1.00 81.97  ? 129 PHE A O     1 
ATOM   952  C CB    . PHE A 1 129 ? 113.399 114.364 137.839 1.00 114.33 ? 129 PHE A CB    1 
ATOM   953  C CG    . PHE A 1 129 ? 114.558 114.698 138.618 1.00 114.33 ? 129 PHE A CG    1 
ATOM   954  C CD1   . PHE A 1 129 ? 115.082 113.834 139.463 1.00 114.33 ? 129 PHE A CD1   1 
ATOM   955  C CD2   . PHE A 1 129 ? 115.085 115.922 138.560 1.00 114.33 ? 129 PHE A CD2   1 
ATOM   956  C CE1   . PHE A 1 129 ? 116.126 114.150 140.211 1.00 114.33 ? 129 PHE A CE1   1 
ATOM   957  C CE2   . PHE A 1 129 ? 116.128 116.243 139.305 1.00 114.33 ? 129 PHE A CE2   1 
ATOM   958  C CZ    . PHE A 1 129 ? 116.656 115.357 140.135 1.00 114.33 ? 129 PHE A CZ    1 
ATOM   959  N N     . ILE A 1 130 ? 111.930 112.050 136.284 1.00 88.81  ? 130 ILE A N     1 
ATOM   960  C CA    . ILE A 1 130 ? 110.614 111.570 135.901 1.00 88.81  ? 130 ILE A CA    1 
ATOM   961  C C     . ILE A 1 130 ? 109.897 111.112 137.131 1.00 88.81  ? 130 ILE A C     1 
ATOM   962  O O     . ILE A 1 130 ? 110.443 110.340 137.916 1.00 88.81  ? 130 ILE A O     1 
ATOM   963  C CB    . ILE A 1 130 ? 110.642 110.417 134.897 1.00 131.41 ? 130 ILE A CB    1 
ATOM   964  C CG1   . ILE A 1 130 ? 111.239 110.876 133.576 1.00 131.41 ? 130 ILE A CG1   1 
ATOM   965  C CG2   . ILE A 1 130 ? 109.263 109.878 134.713 1.00 131.41 ? 130 ILE A CG2   1 
ATOM   966  C CD1   . ILE A 1 130 ? 111.431 109.789 132.514 1.00 131.41 ? 130 ILE A CD1   1 
ATOM   967  N N     . LEU A 1 131 ? 108.687 111.560 137.313 1.00 89.76  ? 131 LEU A N     1 
ATOM   968  C CA    . LEU A 1 131 ? 107.922 111.115 138.454 1.00 89.76  ? 131 LEU A CA    1 
ATOM   969  C C     . LEU A 1 131 ? 106.676 110.397 138.003 1.00 89.76  ? 131 LEU A C     1 
ATOM   970  O O     . LEU A 1 131 ? 106.063 110.778 137.012 1.00 89.76  ? 131 LEU A O     1 
ATOM   971  C CB    . LEU A 1 131 ? 107.535 112.253 139.344 1.00 132.81 ? 131 LEU A CB    1 
ATOM   972  C CG    . LEU A 1 131 ? 108.674 112.955 140.040 1.00 132.81 ? 131 LEU A CG    1 
ATOM   973  C CD1   . LEU A 1 131 ? 109.081 114.175 139.274 1.00 132.81 ? 131 LEU A CD1   1 
ATOM   974  C CD2   . LEU A 1 131 ? 108.301 113.298 141.457 1.00 132.81 ? 131 LEU A CD2   1 
ATOM   975  N N     . THR A 1 132 ? 106.289 109.364 138.725 1.00 97.39  ? 132 THR A N     1 
ATOM   976  C CA    . THR A 1 132 ? 105.059 108.654 138.427 1.00 97.39  ? 132 THR A CA    1 
ATOM   977  C C     . THR A 1 132 ? 104.160 108.731 139.639 1.00 97.39  ? 132 THR A C     1 
ATOM   978  O O     . THR A 1 132 ? 104.544 108.278 140.718 1.00 97.39  ? 132 THR A O     1 
ATOM   979  C CB    . THR A 1 132 ? 105.328 107.201 138.077 1.00 136.33 ? 132 THR A CB    1 
ATOM   980  O OG1   . THR A 1 132 ? 106.233 107.118 136.981 1.00 136.33 ? 132 THR A OG1   1 
ATOM   981  C CG2   . THR A 1 132 ? 104.045 106.501 137.671 1.00 136.33 ? 132 THR A CG2   1 
ATOM   982  N N     . HIS A 1 133 ? 102.966 109.278 139.489 1.00 102.58 ? 133 HIS A N     1 
ATOM   983  C CA    . HIS A 1 133 ? 102.141 109.409 140.675 1.00 102.58 ? 133 HIS A CA    1 
ATOM   984  C C     . HIS A 1 133 ? 100.658 109.572 140.396 1.00 102.58 ? 133 HIS A C     1 
ATOM   985  O O     . HIS A 1 133 ? 100.251 109.966 139.311 1.00 102.58 ? 133 HIS A O     1 
ATOM   986  C CB    . HIS A 1 133 ? 102.600 110.581 141.501 1.00 139.48 ? 133 HIS A CB    1 
ATOM   987  C CG    . HIS A 1 133 ? 102.415 111.881 140.836 1.00 139.48 ? 133 HIS A CG    1 
ATOM   988  N ND1   . HIS A 1 133 ? 101.267 112.612 140.968 1.00 139.48 ? 133 HIS A ND1   1 
ATOM   989  C CD2   . HIS A 1 133 ? 103.226 112.593 140.040 1.00 139.48 ? 133 HIS A CD2   1 
ATOM   990  C CE1   . HIS A 1 133 ? 101.379 113.726 140.285 1.00 139.48 ? 133 HIS A CE1   1 
ATOM   991  N NE2   . HIS A 1 133 ? 102.561 113.740 139.710 1.00 139.48 ? 133 HIS A NE2   1 
ATOM   992  N N     . SER A 1 134 ? 99.852  109.270 141.404 1.00 111.35 ? 134 SER A N     1 
ATOM   993  C CA    . SER A 1 134 ? 98.431  109.560 141.360 1.00 111.35 ? 134 SER A CA    1 
ATOM   994  C C     . SER A 1 134 ? 98.198  111.037 141.544 1.00 111.35 ? 134 SER A C     1 
ATOM   995  O O     . SER A 1 134 ? 98.953  111.693 142.243 1.00 111.35 ? 134 SER A O     1 
ATOM   996  C CB    . SER A 1 134 ? 97.715  108.837 142.464 1.00 149.98 ? 134 SER A CB    1 
ATOM   997  O OG    . SER A 1 134 ? 96.367  109.232 142.535 1.00 149.98 ? 134 SER A OG    1 
ATOM   998  N N     . CYS A 1 135 ? 97.164  111.576 140.904 1.00 113.66 ? 135 CYS A N     1 
ATOM   999  C CA    . CYS A 1 135 ? 96.787  112.973 141.104 1.00 113.66 ? 135 CYS A CA    1 
ATOM   1000 C C     . CYS A 1 135 ? 95.753  113.116 142.170 1.00 113.66 ? 135 CYS A C     1 
ATOM   1001 O O     . CYS A 1 135 ? 95.274  114.218 142.416 1.00 113.66 ? 135 CYS A O     1 
ATOM   1002 C CB    . CYS A 1 135 ? 96.188  113.599 139.862 1.00 153.09 ? 135 CYS A CB    1 
ATOM   1003 S SG    . CYS A 1 135 ? 97.237  113.702 138.495 1.00 153.09 ? 135 CYS A SG    1 
ATOM   1004 N N     . GLY A 1 136 ? 95.339  112.033 142.742 1.00 115.23 ? 136 GLY A N     1 
ATOM   1005 C CA    . GLY A 1 136 ? 94.292  112.085 143.720 1.00 115.23 ? 136 GLY A CA    1 
ATOM   1006 C C     . GLY A 1 136 ? 94.705  111.398 144.982 1.00 115.23 ? 136 GLY A C     1 
ATOM   1007 O O     . GLY A 1 136 ? 95.870  111.371 145.350 1.00 115.23 ? 136 GLY A O     1 
ATOM   1008 N N     . GLY A 1 137 ? 93.718  110.834 145.635 1.00 115.21 ? 137 GLY A N     1 
ATOM   1009 C CA    . GLY A 1 137 ? 93.998  110.068 146.825 1.00 115.21 ? 137 GLY A CA    1 
ATOM   1010 C C     . GLY A 1 137 ? 94.678  110.854 147.923 1.00 115.21 ? 137 GLY A C     1 
ATOM   1011 O O     . GLY A 1 137 ? 94.174  111.873 148.400 1.00 115.21 ? 137 GLY A O     1 
ATOM   1012 N N     . GLY A 1 138 ? 95.777  110.298 148.412 1.00 116.55 ? 138 GLY A N     1 
ATOM   1013 C CA    . GLY A 1 138 ? 96.570  110.815 149.509 1.00 116.55 ? 138 GLY A CA    1 
ATOM   1014 C C     . GLY A 1 138 ? 98.014  111.051 149.156 1.00 116.55 ? 138 GLY A C     1 
ATOM   1015 O O     . GLY A 1 138 ? 98.433  112.152 148.828 1.00 116.55 ? 138 GLY A O     1 
ATOM   1016 N N     . THR A 1 139 ? 98.800  110.004 149.322 1.00 113.52 ? 139 THR A N     1 
ATOM   1017 C CA    . THR A 1 139 ? 100.243 110.103 149.186 1.00 113.52 ? 139 THR A CA    1 
ATOM   1018 C C     . THR A 1 139 ? 100.679 110.602 147.826 1.00 113.52 ? 139 THR A C     1 
ATOM   1019 O O     . THR A 1 139 ? 101.519 111.502 147.747 1.00 113.52 ? 139 THR A O     1 
ATOM   1020 C CB    . THR A 1 139 ? 100.886 108.756 149.442 1.00 158.91 ? 139 THR A CB    1 
ATOM   1021 O OG1   . THR A 1 139 ? 100.554 108.326 150.758 1.00 158.91 ? 139 THR A OG1   1 
ATOM   1022 C CG2   . THR A 1 139 ? 102.385 108.863 149.310 1.00 158.91 ? 139 THR A CG2   1 
ATOM   1023 N N     . GLY A 1 140 ? 100.130 110.045 146.746 1.00 113.81 ? 140 GLY A N     1 
ATOM   1024 C CA    . GLY A 1 140 ? 100.591 110.409 145.414 1.00 113.81 ? 140 GLY A CA    1 
ATOM   1025 C C     . GLY A 1 140 ? 100.399 111.876 145.095 1.00 113.81 ? 140 GLY A C     1 
ATOM   1026 O O     . GLY A 1 140 ? 101.215 112.470 144.387 1.00 113.81 ? 140 GLY A O     1 
ATOM   1027 N N     . SER A 1 141 ? 99.334  112.475 145.594 1.00 114.22 ? 141 SER A N     1 
ATOM   1028 C CA    . SER A 1 141 ? 99.098  113.864 145.286 1.00 114.22 ? 141 SER A CA    1 
ATOM   1029 C C     . SER A 1 141 ? 99.680  114.766 146.340 1.00 114.22 ? 141 SER A C     1 
ATOM   1030 O O     . SER A 1 141 ? 100.350 115.746 146.019 1.00 114.22 ? 141 SER A O     1 
ATOM   1031 C CB    . SER A 1 141 ? 97.613  114.106 145.117 1.00 153.84 ? 141 SER A CB    1 
ATOM   1032 O OG    . SER A 1 141 ? 96.900  113.756 146.277 1.00 153.84 ? 141 SER A OG    1 
ATOM   1033 N N     . GLY A 1 142 ? 99.553  114.395 147.576 1.00 110.09 ? 142 GLY A N     1 
ATOM   1034 C CA    . GLY A 1 142 ? 100.038 115.230 148.639 1.00 110.09 ? 142 GLY A CA    1 
ATOM   1035 C C     . GLY A 1 142 ? 101.540 115.205 148.739 1.00 110.09 ? 142 GLY A C     1 
ATOM   1036 O O     . GLY A 1 142 ? 102.229 116.216 148.535 1.00 110.09 ? 142 GLY A O     1 
ATOM   1037 N N     . PHE A 1 143 ? 102.063 114.055 149.089 1.00 103.41 ? 143 PHE A N     1 
ATOM   1038 C CA    . PHE A 1 143 ? 103.474 113.988 149.334 1.00 103.41 ? 143 PHE A CA    1 
ATOM   1039 C C     . PHE A 1 143 ? 104.176 114.148 148.031 1.00 103.41 ? 143 PHE A C     1 
ATOM   1040 O O     . PHE A 1 143 ? 105.153 114.887 147.938 1.00 103.41 ? 143 PHE A O     1 
ATOM   1041 C CB    . PHE A 1 143 ? 103.796 112.687 150.015 1.00 144.24 ? 143 PHE A CB    1 
ATOM   1042 C CG    . PHE A 1 143 ? 105.160 112.560 150.512 1.00 144.24 ? 143 PHE A CG    1 
ATOM   1043 C CD1   . PHE A 1 143 ? 105.773 113.547 151.144 1.00 144.24 ? 143 PHE A CD1   1 
ATOM   1044 C CD2   . PHE A 1 143 ? 105.780 111.383 150.421 1.00 144.24 ? 143 PHE A CD2   1 
ATOM   1045 C CE1   . PHE A 1 143 ? 107.004 113.384 151.629 1.00 144.24 ? 143 PHE A CE1   1 
ATOM   1046 C CE2   . PHE A 1 143 ? 107.000 111.225 150.902 1.00 144.24 ? 143 PHE A CE2   1 
ATOM   1047 C CZ    . PHE A 1 143 ? 107.612 112.221 151.508 1.00 144.24 ? 143 PHE A CZ    1 
ATOM   1048 N N     . GLY A 1 144 ? 103.633 113.544 146.995 1.00 103.49 ? 144 GLY A N     1 
ATOM   1049 C CA    . GLY A 1 144 ? 104.217 113.691 145.680 1.00 103.49 ? 144 GLY A CA    1 
ATOM   1050 C C     . GLY A 1 144 ? 104.336 115.138 145.225 1.00 103.49 ? 144 GLY A C     1 
ATOM   1051 O O     . GLY A 1 144 ? 105.343 115.510 144.621 1.00 103.49 ? 144 GLY A O     1 
ATOM   1052 N N     . SER A 1 145 ? 103.333 115.991 145.523 1.00 102.63 ? 145 SER A N     1 
ATOM   1053 C CA    . SER A 1 145 ? 103.455 117.378 145.116 1.00 102.63 ? 145 SER A CA    1 
ATOM   1054 C C     . SER A 1 145 ? 104.501 118.105 145.917 1.00 102.63 ? 145 SER A C     1 
ATOM   1055 O O     . SER A 1 145 ? 105.215 118.948 145.365 1.00 102.63 ? 145 SER A O     1 
ATOM   1056 C CB    . SER A 1 145 ? 102.158 118.105 145.261 1.00 138.23 ? 145 SER A CB    1 
ATOM   1057 O OG    . SER A 1 145 ? 101.206 117.596 144.366 1.00 138.23 ? 145 SER A OG    1 
ATOM   1058 N N     . LYS A 1 146 ? 104.642 117.794 147.200 1.00 97.09  ? 146 LYS A N     1 
ATOM   1059 C CA    . LYS A 1 146 ? 105.721 118.443 147.935 1.00 97.09  ? 146 LYS A CA    1 
ATOM   1060 C C     . LYS A 1 146 ? 107.080 117.992 147.436 1.00 97.09  ? 146 LYS A C     1 
ATOM   1061 O O     . LYS A 1 146 ? 108.020 118.785 147.387 1.00 97.09  ? 146 LYS A O     1 
ATOM   1062 C CB    . LYS A 1 146 ? 105.629 118.223 149.420 1.00 145.50 ? 146 LYS A CB    1 
ATOM   1063 C CG    . LYS A 1 146 ? 106.600 119.107 150.160 1.00 145.50 ? 146 LYS A CG    1 
ATOM   1064 C CD    . LYS A 1 146 ? 106.385 119.040 151.629 1.00 145.50 ? 146 LYS A CD    1 
ATOM   1065 C CE    . LYS A 1 146 ? 107.351 119.921 152.387 1.00 145.50 ? 146 LYS A CE    1 
ATOM   1066 N NZ    . LYS A 1 146 ? 107.203 119.762 153.868 1.00 145.50 ? 146 LYS A NZ    1 
ATOM   1067 N N     . ILE A 1 147 ? 107.189 116.735 147.034 1.00 93.80  ? 147 ILE A N     1 
ATOM   1068 C CA    . ILE A 1 147 ? 108.412 116.229 146.453 1.00 93.80  ? 147 ILE A CA    1 
ATOM   1069 C C     . ILE A 1 147 ? 108.732 116.977 145.183 1.00 93.80  ? 147 ILE A C     1 
ATOM   1070 O O     . ILE A 1 147 ? 109.876 117.382 144.971 1.00 93.80  ? 147 ILE A O     1 
ATOM   1071 C CB    . ILE A 1 147 ? 108.305 114.728 146.199 1.00 138.79 ? 147 ILE A CB    1 
ATOM   1072 C CG1   . ILE A 1 147 ? 108.278 114.019 147.532 1.00 138.79 ? 147 ILE A CG1   1 
ATOM   1073 C CG2   . ILE A 1 147 ? 109.445 114.244 145.345 1.00 138.79 ? 147 ILE A CG2   1 
ATOM   1074 C CD1   . ILE A 1 147 ? 107.875 112.575 147.480 1.00 138.79 ? 147 ILE A CD1   1 
ATOM   1075 N N     . LEU A 1 148 ? 107.731 117.189 144.324 1.00 87.43  ? 148 LEU A N     1 
ATOM   1076 C CA    . LEU A 1 148 ? 107.935 117.913 143.068 1.00 87.43  ? 148 LEU A CA    1 
ATOM   1077 C C     . LEU A 1 148 ? 108.449 119.294 143.336 1.00 87.43  ? 148 LEU A C     1 
ATOM   1078 O O     . LEU A 1 148 ? 109.412 119.757 142.705 1.00 87.43  ? 148 LEU A O     1 
ATOM   1079 C CB    . LEU A 1 148 ? 106.635 118.003 142.289 1.00 129.36 ? 148 LEU A CB    1 
ATOM   1080 C CG    . LEU A 1 148 ? 106.632 118.759 141.011 1.00 129.36 ? 148 LEU A CG    1 
ATOM   1081 C CD1   . LEU A 1 148 ? 107.513 118.104 140.010 1.00 129.36 ? 148 LEU A CD1   1 
ATOM   1082 C CD2   . LEU A 1 148 ? 105.227 118.866 140.473 1.00 129.36 ? 148 LEU A CD2   1 
ATOM   1083 N N     . LYS A 1 149 ? 107.844 119.949 144.296 1.00 89.26  ? 149 LYS A N     1 
ATOM   1084 C CA    . LYS A 1 149 ? 108.230 121.293 144.628 1.00 89.26  ? 149 LYS A CA    1 
ATOM   1085 C C     . LYS A 1 149 ? 109.646 121.326 145.112 1.00 89.26  ? 149 LYS A C     1 
ATOM   1086 O O     . LYS A 1 149 ? 110.463 122.140 144.654 1.00 89.26  ? 149 LYS A O     1 
ATOM   1087 C CB    . LYS A 1 149 ? 107.311 121.839 145.694 1.00 133.77 ? 149 LYS A CB    1 
ATOM   1088 C CG    . LYS A 1 149 ? 107.571 123.249 146.183 1.00 133.77 ? 149 LYS A CG    1 
ATOM   1089 C CD    . LYS A 1 149 ? 106.494 123.647 147.176 1.00 133.77 ? 149 LYS A CD    1 
ATOM   1090 C CE    . LYS A 1 149 ? 106.573 125.090 147.654 1.00 133.77 ? 149 LYS A CE    1 
ATOM   1091 N NZ    . LYS A 1 149 ? 107.776 125.400 148.495 1.00 133.77 ? 149 LYS A NZ    1 
ATOM   1092 N N     . THR A 1 150 ? 109.970 120.430 146.001 1.00 87.64  ? 150 THR A N     1 
ATOM   1093 C CA    . THR A 1 150 ? 111.282 120.438 146.608 1.00 87.64  ? 150 THR A CA    1 
ATOM   1094 C C     . THR A 1 150 ? 112.363 120.191 145.588 1.00 87.64  ? 150 THR A C     1 
ATOM   1095 O O     . THR A 1 150 ? 113.411 120.837 145.613 1.00 87.64  ? 150 THR A O     1 
ATOM   1096 C CB    . THR A 1 150 ? 111.352 119.375 147.686 1.00 122.68 ? 150 THR A CB    1 
ATOM   1097 O OG1   . THR A 1 150 ? 110.348 119.625 148.675 1.00 122.68 ? 150 THR A OG1   1 
ATOM   1098 C CG2   . THR A 1 150 ? 112.706 119.389 148.343 1.00 122.68 ? 150 THR A CG2   1 
ATOM   1099 N N     . ILE A 1 151 ? 112.139 119.260 144.684 1.00 85.56  ? 151 ILE A N     1 
ATOM   1100 C CA    . ILE A 1 151 ? 113.167 118.966 143.714 1.00 85.56  ? 151 ILE A CA    1 
ATOM   1101 C C     . ILE A 1 151 ? 113.430 120.163 142.867 1.00 85.56  ? 151 ILE A C     1 
ATOM   1102 O O     . ILE A 1 151 ? 114.587 120.486 142.614 1.00 85.56  ? 151 ILE A O     1 
ATOM   1103 C CB    . ILE A 1 151 ? 112.813 117.764 142.845 1.00 126.60 ? 151 ILE A CB    1 
ATOM   1104 C CG1   . ILE A 1 151 ? 112.825 116.547 143.698 1.00 126.60 ? 151 ILE A CG1   1 
ATOM   1105 C CG2   . ILE A 1 151 ? 113.800 117.606 141.698 1.00 126.60 ? 151 ILE A CG2   1 
ATOM   1106 C CD1   . ILE A 1 151 ? 112.195 115.373 143.077 1.00 126.60 ? 151 ILE A CD1   1 
ATOM   1107 N N     . ARG A 1 152 ? 112.396 120.835 142.380 1.00 83.94  ? 152 ARG A N     1 
ATOM   1108 C CA    . ARG A 1 152 ? 112.739 121.966 141.532 1.00 83.94  ? 152 ARG A CA    1 
ATOM   1109 C C     . ARG A 1 152 ? 113.482 123.015 142.293 1.00 83.94  ? 152 ARG A C     1 
ATOM   1110 O O     . ARG A 1 152 ? 114.402 123.632 141.755 1.00 83.94  ? 152 ARG A O     1 
ATOM   1111 C CB    . ARG A 1 152 ? 111.571 122.634 140.865 1.00 123.24 ? 152 ARG A CB    1 
ATOM   1112 C CG    . ARG A 1 152 ? 112.087 123.678 139.993 1.00 123.24 ? 152 ARG A CG    1 
ATOM   1113 C CD    . ARG A 1 152 ? 111.150 124.258 139.158 1.00 123.24 ? 152 ARG A CD    1 
ATOM   1114 N NE    . ARG A 1 152 ? 110.697 123.298 138.204 1.00 123.24 ? 152 ARG A NE    1 
ATOM   1115 C CZ    . ARG A 1 152 ? 111.298 122.969 137.076 1.00 123.24 ? 152 ARG A CZ    1 
ATOM   1116 N NH1   . ARG A 1 152 ? 112.457 123.485 136.719 1.00 123.24 ? 152 ARG A NH1   1 
ATOM   1117 N NH2   . ARG A 1 152 ? 110.689 122.114 136.276 1.00 123.24 ? 152 ARG A NH2   1 
ATOM   1118 N N     . GLU A 1 153 ? 113.128 123.240 143.535 1.00 87.18  ? 153 GLU A N     1 
ATOM   1119 C CA    . GLU A 1 153 ? 113.869 124.242 144.270 1.00 87.18  ? 153 GLU A CA    1 
ATOM   1120 C C     . GLU A 1 153 ? 115.340 123.882 144.377 1.00 87.18  ? 153 GLU A C     1 
ATOM   1121 O O     . GLU A 1 153 ? 116.203 124.751 144.257 1.00 87.18  ? 153 GLU A O     1 
ATOM   1122 C CB    . GLU A 1 153 ? 113.253 124.431 145.632 1.00 117.10 ? 153 GLU A CB    1 
ATOM   1123 C CG    . GLU A 1 153 ? 111.911 125.070 145.570 1.00 117.10 ? 153 GLU A CG    1 
ATOM   1124 C CD    . GLU A 1 153 ? 111.205 125.063 146.880 1.00 117.10 ? 153 GLU A CD    1 
ATOM   1125 O OE1   . GLU A 1 153 ? 111.729 124.488 147.823 1.00 117.10 ? 153 GLU A OE1   1 
ATOM   1126 O OE2   . GLU A 1 153 ? 110.113 125.635 146.965 1.00 117.10 ? 153 GLU A OE2   1 
ATOM   1127 N N     . ARG A 1 154 ? 115.652 122.619 144.588 1.00 86.06  ? 154 ARG A N     1 
ATOM   1128 C CA    . ARG A 1 154 ? 117.053 122.241 144.698 1.00 86.06  ? 154 ARG A CA    1 
ATOM   1129 C C     . ARG A 1 154 ? 117.775 122.191 143.364 1.00 86.06  ? 154 ARG A C     1 
ATOM   1130 O O     . ARG A 1 154 ? 118.979 122.426 143.317 1.00 86.06  ? 154 ARG A O     1 
ATOM   1131 C CB    . ARG A 1 154 ? 117.188 120.903 145.398 1.00 126.35 ? 154 ARG A CB    1 
ATOM   1132 C CG    . ARG A 1 154 ? 116.852 120.950 146.848 1.00 126.35 ? 154 ARG A CG    1 
ATOM   1133 C CD    . ARG A 1 154 ? 117.122 119.660 147.520 1.00 126.35 ? 154 ARG A CD    1 
ATOM   1134 N NE    . ARG A 1 154 ? 116.758 119.705 148.925 1.00 126.35 ? 154 ARG A NE    1 
ATOM   1135 C CZ    . ARG A 1 154 ? 117.158 118.823 149.827 1.00 126.35 ? 154 ARG A CZ    1 
ATOM   1136 N NH1   . ARG A 1 154 ? 117.976 117.837 149.507 1.00 126.35 ? 154 ARG A NH1   1 
ATOM   1137 N NH2   . ARG A 1 154 ? 116.735 118.937 151.084 1.00 126.35 ? 154 ARG A NH2   1 
ATOM   1138 N N     . TYR A 1 155 ? 117.089 121.876 142.278 1.00 87.04  ? 155 TYR A N     1 
ATOM   1139 C CA    . TYR A 1 155 ? 117.704 121.774 140.956 1.00 87.04  ? 155 TYR A CA    1 
ATOM   1140 C C     . TYR A 1 155 ? 116.911 122.604 139.949 1.00 87.04  ? 155 TYR A C     1 
ATOM   1141 O O     . TYR A 1 155 ? 116.214 122.042 139.105 1.00 87.04  ? 155 TYR A O     1 
ATOM   1142 C CB    . TYR A 1 155 ? 117.759 120.321 140.484 1.00 120.47 ? 155 TYR A CB    1 
ATOM   1143 C CG    . TYR A 1 155 ? 118.267 119.331 141.468 1.00 120.47 ? 155 TYR A CG    1 
ATOM   1144 C CD1   . TYR A 1 155 ? 119.582 119.063 141.626 1.00 120.47 ? 155 TYR A CD1   1 
ATOM   1145 C CD2   . TYR A 1 155 ? 117.390 118.648 142.212 1.00 120.47 ? 155 TYR A CD2   1 
ATOM   1146 C CE1   . TYR A 1 155 ? 119.988 118.133 142.548 1.00 120.47 ? 155 TYR A CE1   1 
ATOM   1147 C CE2   . TYR A 1 155 ? 117.769 117.743 143.104 1.00 120.47 ? 155 TYR A CE2   1 
ATOM   1148 C CZ    . TYR A 1 155 ? 119.060 117.476 143.280 1.00 120.47 ? 155 TYR A CZ    1 
ATOM   1149 O OH    . TYR A 1 155 ? 119.396 116.530 144.217 1.00 120.47 ? 155 TYR A OH    1 
ATOM   1150 N N     . PRO A 1 156 ? 117.037 123.932 139.983 1.00 80.67  ? 156 PRO A N     1 
ATOM   1151 C CA    . PRO A 1 156 ? 116.214 124.863 139.206 1.00 80.67  ? 156 PRO A CA    1 
ATOM   1152 C C     . PRO A 1 156 ? 116.206 124.722 137.716 1.00 80.67  ? 156 PRO A C     1 
ATOM   1153 O O     . PRO A 1 156 ? 115.261 125.165 137.067 1.00 80.67  ? 156 PRO A O     1 
ATOM   1154 C CB    . PRO A 1 156 ? 116.846 126.198 139.573 1.00 251.62 ? 156 PRO A CB    1 
ATOM   1155 C CG    . PRO A 1 156 ? 117.455 125.983 140.848 1.00 251.62 ? 156 PRO A CG    1 
ATOM   1156 C CD    . PRO A 1 156 ? 117.981 124.624 140.831 1.00 251.62 ? 156 PRO A CD    1 
ATOM   1157 N N     . LYS A 1 157 ? 117.235 124.172 137.125 1.00 82.05  ? 157 LYS A N     1 
ATOM   1158 C CA    . LYS A 1 157 ? 117.295 124.080 135.681 1.00 82.05  ? 157 LYS A CA    1 
ATOM   1159 C C     . LYS A 1 157 ? 117.100 122.675 135.161 1.00 82.05  ? 157 LYS A C     1 
ATOM   1160 O O     . LYS A 1 157 ? 117.295 122.433 133.972 1.00 82.05  ? 157 LYS A O     1 
ATOM   1161 C CB    . LYS A 1 157 ? 118.637 124.600 135.184 1.00 122.96 ? 157 LYS A CB    1 
ATOM   1162 C CG    . LYS A 1 157 ? 118.944 126.052 135.517 1.00 122.96 ? 157 LYS A CG    1 
ATOM   1163 C CD    . LYS A 1 157 ? 118.057 127.028 134.769 1.00 122.96 ? 157 LYS A CD    1 
ATOM   1164 C CE    . LYS A 1 157 ? 118.479 128.452 135.036 1.00 122.96 ? 157 LYS A CE    1 
ATOM   1165 N NZ    . LYS A 1 157 ? 117.684 129.421 134.265 1.00 122.96 ? 157 LYS A NZ    1 
ATOM   1166 N N     . VAL A 1 158 ? 116.775 121.719 136.002 1.00 79.25  ? 158 VAL A N     1 
ATOM   1167 C CA    . VAL A 1 158 ? 116.655 120.335 135.574 1.00 79.25  ? 158 VAL A CA    1 
ATOM   1168 C C     . VAL A 1 158 ? 115.201 120.062 135.228 1.00 79.25  ? 158 VAL A C     1 
ATOM   1169 O O     . VAL A 1 158 ? 114.342 120.206 136.094 1.00 79.25  ? 158 VAL A O     1 
ATOM   1170 C CB    . VAL A 1 158 ? 117.133 119.408 136.671 1.00 115.23 ? 158 VAL A CB    1 
ATOM   1171 C CG1   . VAL A 1 158 ? 116.917 118.027 136.269 1.00 115.23 ? 158 VAL A CG1   1 
ATOM   1172 C CG2   . VAL A 1 158 ? 118.579 119.638 136.897 1.00 115.23 ? 158 VAL A CG2   1 
ATOM   1173 N N     . PRO A 1 159 ? 114.896 119.655 134.033 1.00 81.53  ? 159 PRO A N     1 
ATOM   1174 C CA    . PRO A 1 159 ? 113.525 119.489 133.638 1.00 81.53  ? 159 PRO A CA    1 
ATOM   1175 C C     . PRO A 1 159 ? 112.913 118.343 134.381 1.00 81.53  ? 159 PRO A C     1 
ATOM   1176 O O     . PRO A 1 159 ? 113.579 117.355 134.656 1.00 81.53  ? 159 PRO A O     1 
ATOM   1177 C CB    . PRO A 1 159 ? 113.633 119.184 132.162 1.00 254.30 ? 159 PRO A CB    1 
ATOM   1178 C CG    . PRO A 1 159 ? 114.962 118.629 132.017 1.00 254.30 ? 159 PRO A CG    1 
ATOM   1179 C CD    . PRO A 1 159 ? 115.832 119.322 133.008 1.00 254.30 ? 159 PRO A CD    1 
ATOM   1180 N N     . ILE A 1 160 ? 111.637 118.471 134.701 1.00 88.27  ? 160 ILE A N     1 
ATOM   1181 C CA    . ILE A 1 160 ? 110.903 117.430 135.392 1.00 88.27  ? 160 ILE A CA    1 
ATOM   1182 C C     . ILE A 1 160 ? 109.684 117.026 134.604 1.00 88.27  ? 160 ILE A C     1 
ATOM   1183 O O     . ILE A 1 160 ? 108.833 117.862 134.295 1.00 88.27  ? 160 ILE A O     1 
ATOM   1184 C CB    . ILE A 1 160 ? 110.472 117.895 136.774 1.00 130.61 ? 160 ILE A CB    1 
ATOM   1185 C CG1   . ILE A 1 160 ? 111.671 118.300 137.601 1.00 130.61 ? 160 ILE A CG1   1 
ATOM   1186 C CG2   . ILE A 1 160 ? 109.758 116.791 137.400 1.00 130.61 ? 160 ILE A CG2   1 
ATOM   1187 C CD1   . ILE A 1 160 ? 111.333 118.961 138.921 1.00 130.61 ? 160 ILE A CD1   1 
ATOM   1188 N N     . PHE A 1 161 ? 109.575 115.754 134.307 1.00 89.62  ? 161 PHE A N     1 
ATOM   1189 C CA    . PHE A 1 161 ? 108.443 115.215 133.606 1.00 89.62  ? 161 PHE A CA    1 
ATOM   1190 C C     . PHE A 1 161 ? 107.638 114.369 134.539 1.00 89.62  ? 161 PHE A C     1 
ATOM   1191 O O     . PHE A 1 161 ? 108.194 113.552 135.273 1.00 89.62  ? 161 PHE A O     1 
ATOM   1192 C CB    . PHE A 1 161 ? 108.865 114.335 132.464 1.00 125.01 ? 161 PHE A CB    1 
ATOM   1193 C CG    . PHE A 1 161 ? 109.279 115.053 131.273 1.00 125.01 ? 161 PHE A CG    1 
ATOM   1194 C CD1   . PHE A 1 161 ? 110.424 115.829 131.269 1.00 125.01 ? 161 PHE A CD1   1 
ATOM   1195 C CD2   . PHE A 1 161 ? 108.545 114.936 130.119 1.00 125.01 ? 161 PHE A CD2   1 
ATOM   1196 C CE1   . PHE A 1 161 ? 110.804 116.484 130.135 1.00 125.01 ? 161 PHE A CE1   1 
ATOM   1197 C CE2   . PHE A 1 161 ? 108.924 115.585 128.992 1.00 125.01 ? 161 PHE A CE2   1 
ATOM   1198 C CZ    . PHE A 1 161 ? 110.053 116.360 128.994 1.00 125.01 ? 161 PHE A CZ    1 
ATOM   1199 N N     . THR A 1 162 ? 106.349 114.506 134.504 1.00 91.26  ? 162 THR A N     1 
ATOM   1200 C CA    . THR A 1 162 ? 105.567 113.662 135.357 1.00 91.26  ? 162 THR A CA    1 
ATOM   1201 C C     . THR A 1 162 ? 104.574 112.897 134.546 1.00 91.26  ? 162 THR A C     1 
ATOM   1202 O O     . THR A 1 162 ? 104.030 113.407 133.572 1.00 91.26  ? 162 THR A O     1 
ATOM   1203 C CB    . THR A 1 162 ? 104.826 114.441 136.386 1.00 127.75 ? 162 THR A CB    1 
ATOM   1204 O OG1   . THR A 1 162 ? 103.848 115.242 135.742 1.00 127.75 ? 162 THR A OG1   1 
ATOM   1205 C CG2   . THR A 1 162 ? 105.751 115.363 137.152 1.00 127.75 ? 162 THR A CG2   1 
ATOM   1206 N N     . PHE A 1 163 ? 104.303 111.699 134.972 1.00 94.88  ? 163 PHE A N     1 
ATOM   1207 C CA    . PHE A 1 163 ? 103.232 110.924 134.415 1.00 94.88  ? 163 PHE A CA    1 
ATOM   1208 C C     . PHE A 1 163 ? 102.223 110.863 135.510 1.00 94.88  ? 163 PHE A C     1 
ATOM   1209 O O     . PHE A 1 163 ? 102.514 110.323 136.577 1.00 94.88  ? 163 PHE A O     1 
ATOM   1210 C CB    . PHE A 1 163 ? 103.649 109.525 134.051 1.00 132.34 ? 163 PHE A CB    1 
ATOM   1211 C CG    . PHE A 1 163 ? 104.544 109.437 132.907 1.00 132.34 ? 163 PHE A CG    1 
ATOM   1212 C CD1   . PHE A 1 163 ? 105.883 109.470 133.072 1.00 132.34 ? 163 PHE A CD1   1 
ATOM   1213 C CD2   . PHE A 1 163 ? 104.041 109.278 131.656 1.00 132.34 ? 163 PHE A CD2   1 
ATOM   1214 C CE1   . PHE A 1 163 ? 106.711 109.362 132.011 1.00 132.34 ? 163 PHE A CE1   1 
ATOM   1215 C CE2   . PHE A 1 163 ? 104.862 109.172 130.587 1.00 132.34 ? 163 PHE A CE2   1 
ATOM   1216 C CZ    . PHE A 1 163 ? 106.202 109.212 130.766 1.00 132.34 ? 163 PHE A CZ    1 
ATOM   1217 N N     . SER A 1 164 ? 101.066 111.434 135.304 1.00 106.18 ? 164 SER A N     1 
ATOM   1218 C CA    . SER A 1 164 ? 100.186 111.494 136.444 1.00 106.18 ? 164 SER A CA    1 
ATOM   1219 C C     . SER A 1 164 ? 98.799  111.016 136.093 1.00 106.18 ? 164 SER A C     1 
ATOM   1220 O O     . SER A 1 164 ? 98.312  111.235 134.984 1.00 106.18 ? 164 SER A O     1 
ATOM   1221 C CB    . SER A 1 164 ? 100.176 112.872 137.001 1.00 143.02 ? 164 SER A CB    1 
ATOM   1222 O OG    . SER A 1 164 ? 99.609  113.785 136.109 1.00 143.02 ? 164 SER A OG    1 
ATOM   1223 N N     . ILE A 1 165 ? 98.166  110.358 137.048 1.00 111.90 ? 165 ILE A N     1 
ATOM   1224 C CA    . ILE A 1 165 ? 96.888  109.732 136.808 1.00 111.90 ? 165 ILE A CA    1 
ATOM   1225 C C     . ILE A 1 165 ? 95.742  110.482 137.456 1.00 111.90 ? 165 ILE A C     1 
ATOM   1226 O O     . ILE A 1 165 ? 95.599  110.500 138.674 1.00 111.90 ? 165 ILE A O     1 
ATOM   1227 C CB    . ILE A 1 165 ? 96.861  108.295 137.300 1.00 165.57 ? 165 ILE A CB    1 
ATOM   1228 C CG1   . ILE A 1 165 ? 98.050  107.496 136.756 1.00 165.57 ? 165 ILE A CG1   1 
ATOM   1229 C CG2   . ILE A 1 165 ? 95.507  107.646 136.891 1.00 165.57 ? 165 ILE A CG2   1 
ATOM   1230 C CD1   . ILE A 1 165 ? 98.194  107.434 135.242 1.00 165.57 ? 165 ILE A CD1   1 
ATOM   1231 N N     . PHE A 1 166 ? 94.855  110.974 136.635 1.00 113.61 ? 166 PHE A N     1 
ATOM   1232 C CA    . PHE A 1 166 ? 93.701  111.661 137.171 1.00 113.61 ? 166 PHE A CA    1 
ATOM   1233 C C     . PHE A 1 166 ? 92.582  110.655 137.459 1.00 113.61 ? 166 PHE A C     1 
ATOM   1234 O O     . PHE A 1 166 ? 92.404  109.690 136.720 1.00 113.61 ? 166 PHE A O     1 
ATOM   1235 C CB    . PHE A 1 166 ? 93.271  112.769 136.216 1.00 158.47 ? 166 PHE A CB    1 
ATOM   1236 C CG    . PHE A 1 166 ? 94.205  113.940 136.229 1.00 158.47 ? 166 PHE A CG    1 
ATOM   1237 C CD1   . PHE A 1 166 ? 94.030  114.964 137.089 1.00 158.47 ? 166 PHE A CD1   1 
ATOM   1238 C CD2   . PHE A 1 166 ? 95.276  113.984 135.389 1.00 158.47 ? 166 PHE A CD2   1 
ATOM   1239 C CE1   . PHE A 1 166 ? 94.887  116.011 137.106 1.00 158.47 ? 166 PHE A CE1   1 
ATOM   1240 C CE2   . PHE A 1 166 ? 96.133  115.033 135.409 1.00 158.47 ? 166 PHE A CE2   1 
ATOM   1241 C CZ    . PHE A 1 166 ? 95.933  116.044 136.269 1.00 158.47 ? 166 PHE A CZ    1 
ATOM   1242 N N     . PRO A 1 167 ? 91.889  110.908 138.549 1.00 113.75 ? 167 PRO A N     1 
ATOM   1243 C CA    . PRO A 1 167 ? 90.862  110.040 139.100 1.00 113.75 ? 167 PRO A CA    1 
ATOM   1244 C C     . PRO A 1 167 ? 89.589  110.043 138.303 1.00 113.75 ? 167 PRO A C     1 
ATOM   1245 O O     . PRO A 1 167 ? 89.330  110.944 137.520 1.00 113.75 ? 167 PRO A O     1 
ATOM   1246 C CB    . PRO A 1 167 ? 90.594  110.696 140.430 1.00 354.79 ? 167 PRO A CB    1 
ATOM   1247 C CG    . PRO A 1 167 ? 90.864  112.113 140.129 1.00 354.79 ? 167 PRO A CG    1 
ATOM   1248 C CD    . PRO A 1 167 ? 92.031  112.127 139.291 1.00 354.79 ? 167 PRO A CD    1 
ATOM   1249 N N     . SER A 1 168 ? 88.746  109.057 138.585 1.00 120.55 ? 168 SER A N     1 
ATOM   1250 C CA    . SER A 1 168 ? 87.433  108.981 138.002 1.00 120.55 ? 168 SER A CA    1 
ATOM   1251 C C     . SER A 1 168 ? 86.432  108.366 138.962 1.00 120.55 ? 168 SER A C     1 
ATOM   1252 O O     . SER A 1 168 ? 86.745  107.365 139.613 1.00 120.55 ? 168 SER A O     1 
ATOM   1253 C CB    . SER A 1 168 ? 87.429  108.165 136.730 1.00 162.37 ? 168 SER A CB    1 
ATOM   1254 O OG    . SER A 1 168 ? 86.097  107.976 136.305 1.00 162.37 ? 168 SER A OG    1 
ATOM   1255 N N     . PRO A 1 169 ? 85.223  108.933 139.016 1.00 125.66 ? 169 PRO A N     1 
ATOM   1256 C CA    . PRO A 1 169 ? 84.129  108.450 139.881 1.00 125.66 ? 169 PRO A CA    1 
ATOM   1257 C C     . PRO A 1 169 ? 83.628  107.069 139.511 1.00 125.66 ? 169 PRO A C     1 
ATOM   1258 O O     . PRO A 1 169 ? 82.867  106.460 140.276 1.00 125.66 ? 169 PRO A O     1 
ATOM   1259 C CB    . PRO A 1 169 ? 83.036  109.514 139.661 1.00 391.95 ? 169 PRO A CB    1 
ATOM   1260 C CG    . PRO A 1 169 ? 83.351  110.107 138.300 1.00 391.95 ? 169 PRO A CG    1 
ATOM   1261 C CD    . PRO A 1 169 ? 84.842  110.097 138.206 1.00 391.95 ? 169 PRO A CD    1 
ATOM   1262 N N     . LYS A 1 170 ? 84.017  106.568 138.343 1.00 126.38 ? 170 LYS A N     1 
ATOM   1263 C CA    . LYS A 1 170 ? 83.645  105.224 137.942 1.00 126.38 ? 170 LYS A CA    1 
ATOM   1264 C C     . LYS A 1 170 ? 84.427  104.209 138.738 1.00 126.38 ? 170 LYS A C     1 
ATOM   1265 O O     . LYS A 1 170 ? 84.040  103.039 138.803 1.00 126.38 ? 170 LYS A O     1 
ATOM   1266 C CB    . LYS A 1 170 ? 83.926  105.013 136.457 1.00 189.40 ? 170 LYS A CB    1 
ATOM   1267 C CG    . LYS A 1 170 ? 83.177  105.938 135.496 1.00 189.40 ? 170 LYS A CG    1 
ATOM   1268 C CD    . LYS A 1 170 ? 81.714  105.546 135.316 1.00 189.40 ? 170 LYS A CD    1 
ATOM   1269 C CE    . LYS A 1 170 ? 80.967  106.514 134.374 1.00 189.40 ? 170 LYS A CE    1 
ATOM   1270 N NZ    . LYS A 1 170 ? 81.473  106.501 132.952 1.00 189.40 ? 170 LYS A NZ    1 
ATOM   1271 N N     . ILE A 1 171 ? 85.537  104.646 139.321 1.00 128.14 ? 171 ILE A N     1 
ATOM   1272 C CA    . ILE A 1 171 ? 86.451  103.786 140.046 1.00 128.14 ? 171 ILE A CA    1 
ATOM   1273 C C     . ILE A 1 171 ? 86.451  104.072 141.550 1.00 128.14 ? 171 ILE A C     1 
ATOM   1274 O O     . ILE A 1 171 ? 86.417  103.136 142.351 1.00 128.14 ? 171 ILE A O     1 
ATOM   1275 C CB    . ILE A 1 171 ? 87.866  103.888 139.449 1.00 189.60 ? 171 ILE A CB    1 
ATOM   1276 C CG1   . ILE A 1 171 ? 87.788  103.378 138.005 1.00 189.60 ? 171 ILE A CG1   1 
ATOM   1277 C CG2   . ILE A 1 171 ? 88.875  103.092 140.298 1.00 189.60 ? 171 ILE A CG2   1 
ATOM   1278 C CD1   . ILE A 1 171 ? 88.965  103.676 137.198 1.00 189.60 ? 171 ILE A CD1   1 
ATOM   1279 N N     . SER A 1 172 ? 86.512  105.351 141.963 1.00 133.77 ? 172 SER A N     1 
ATOM   1280 C CA    . SER A 1 172 ? 86.608  105.668 143.394 1.00 133.77 ? 172 SER A CA    1 
ATOM   1281 C C     . SER A 1 172 ? 85.448  106.479 143.969 1.00 133.77 ? 172 SER A C     1 
ATOM   1282 O O     . SER A 1 172 ? 85.104  107.559 143.474 1.00 133.77 ? 172 SER A O     1 
ATOM   1283 C CB    . SER A 1 172 ? 87.877  106.417 143.747 1.00 180.18 ? 172 SER A CB    1 
ATOM   1284 O OG    . SER A 1 172 ? 87.824  106.739 145.123 1.00 180.18 ? 172 SER A OG    1 
ATOM   1285 N N     . GLU A 1 173 ? 84.921  105.975 145.083 1.00 137.12 ? 173 GLU A N     1 
ATOM   1286 C CA    . GLU A 1 173 ? 83.844  106.573 145.862 1.00 137.12 ? 173 GLU A CA    1 
ATOM   1287 C C     . GLU A 1 173 ? 84.343  107.645 146.820 1.00 137.12 ? 173 GLU A C     1 
ATOM   1288 O O     . GLU A 1 173 ? 83.536  108.300 147.494 1.00 137.12 ? 173 GLU A O     1 
ATOM   1289 C CB    . GLU A 1 173 ? 83.112  105.483 146.663 1.00 184.17 ? 173 GLU A CB    1 
ATOM   1290 C CG    . GLU A 1 173 ? 83.867  104.933 147.902 1.00 184.17 ? 173 GLU A CG    1 
ATOM   1291 C CD    . GLU A 1 173 ? 84.857  103.847 147.571 1.00 184.17 ? 173 GLU A CD    1 
ATOM   1292 O OE1   . GLU A 1 173 ? 85.250  103.747 146.410 1.00 184.17 ? 173 GLU A OE1   1 
ATOM   1293 O OE2   . GLU A 1 173 ? 85.241  103.095 148.469 1.00 184.17 ? 173 GLU A OE2   1 
ATOM   1294 N N     . THR A 1 174 ? 85.655  107.819 146.914 1.00 133.51 ? 174 THR A N     1 
ATOM   1295 C CA    . THR A 1 174 ? 86.238  108.717 147.894 1.00 133.51 ? 174 THR A CA    1 
ATOM   1296 C C     . THR A 1 174 ? 86.109  110.151 147.416 1.00 133.51 ? 174 THR A C     1 
ATOM   1297 O O     . THR A 1 174 ? 87.095  110.807 147.082 1.00 133.51 ? 174 THR A O     1 
ATOM   1298 C CB    . THR A 1 174 ? 87.701  108.381 148.115 1.00 186.89 ? 174 THR A CB    1 
ATOM   1299 O OG1   . THR A 1 174 ? 88.378  108.420 146.858 1.00 186.89 ? 174 THR A OG1   1 
ATOM   1300 C CG2   . THR A 1 174 ? 87.840  107.006 148.701 1.00 186.89 ? 174 THR A CG2   1 
ATOM   1301 N N     . VAL A 1 175 ? 84.885  110.662 147.441 1.00 129.61 ? 175 VAL A N     1 
ATOM   1302 C CA    . VAL A 1 175 ? 84.669  111.965 146.827 1.00 129.61 ? 175 VAL A CA    1 
ATOM   1303 C C     . VAL A 1 175 ? 85.019  113.076 147.804 1.00 129.61 ? 175 VAL A C     1 
ATOM   1304 O O     . VAL A 1 175 ? 84.165  113.799 148.330 1.00 129.61 ? 175 VAL A O     1 
ATOM   1305 C CB    . VAL A 1 175 ? 83.232  112.087 146.290 1.00 188.46 ? 175 VAL A CB    1 
ATOM   1306 C CG1   . VAL A 1 175 ? 83.012  113.440 145.596 1.00 188.46 ? 175 VAL A CG1   1 
ATOM   1307 C CG2   . VAL A 1 175 ? 82.981  110.961 145.297 1.00 188.46 ? 175 VAL A CG2   1 
ATOM   1308 N N     . VAL A 1 176 ? 86.314  113.239 147.953 1.00 123.75 ? 176 VAL A N     1 
ATOM   1309 C CA    . VAL A 1 176 ? 86.991  114.337 148.591 1.00 123.75 ? 176 VAL A CA    1 
ATOM   1310 C C     . VAL A 1 176 ? 87.953  114.735 147.509 1.00 123.75 ? 176 VAL A C     1 
ATOM   1311 O O     . VAL A 1 176 ? 88.554  115.816 147.516 1.00 123.75 ? 176 VAL A O     1 
ATOM   1312 C CB    . VAL A 1 176 ? 87.701  113.878 149.853 1.00 179.94 ? 176 VAL A CB    1 
ATOM   1313 C CG1   . VAL A 1 176 ? 86.682  113.310 150.802 1.00 179.94 ? 176 VAL A CG1   1 
ATOM   1314 C CG2   . VAL A 1 176 ? 88.769  112.822 149.518 1.00 179.94 ? 176 VAL A CG2   1 
ATOM   1315 N N     . GLU A 1 177 ? 88.014  113.839 146.537 1.00 120.81 ? 177 GLU A N     1 
ATOM   1316 C CA    . GLU A 1 177 ? 88.924  113.896 145.416 1.00 120.81 ? 177 GLU A CA    1 
ATOM   1317 C C     . GLU A 1 177 ? 88.944  115.192 144.642 1.00 120.81 ? 177 GLU A C     1 
ATOM   1318 O O     . GLU A 1 177 ? 90.038  115.619 144.260 1.00 120.81 ? 177 GLU A O     1 
ATOM   1319 C CB    . GLU A 1 177 ? 88.581  112.735 144.496 1.00 162.27 ? 177 GLU A CB    1 
ATOM   1320 C CG    . GLU A 1 177 ? 89.450  112.669 143.350 1.00 162.27 ? 177 GLU A CG    1 
ATOM   1321 C CD    . GLU A 1 177 ? 90.839  112.428 143.769 1.00 162.27 ? 177 GLU A CD    1 
ATOM   1322 O OE1   . GLU A 1 177 ? 91.067  111.631 144.689 1.00 162.27 ? 177 GLU A OE1   1 
ATOM   1323 O OE2   . GLU A 1 177 ? 91.703  113.083 143.213 1.00 162.27 ? 177 GLU A OE2   1 
ATOM   1324 N N     . PRO A 1 178 ? 87.842  115.854 144.362 1.00 118.80 ? 178 PRO A N     1 
ATOM   1325 C CA    . PRO A 1 178 ? 87.926  117.109 143.624 1.00 118.80 ? 178 PRO A CA    1 
ATOM   1326 C C     . PRO A 1 178 ? 88.778  118.144 144.331 1.00 118.80 ? 178 PRO A C     1 
ATOM   1327 O O     . PRO A 1 178 ? 89.303  119.065 143.688 1.00 118.80 ? 178 PRO A O     1 
ATOM   1328 C CB    . PRO A 1 178 ? 86.463  117.522 143.517 1.00 370.54 ? 178 PRO A CB    1 
ATOM   1329 C CG    . PRO A 1 178 ? 85.715  116.218 143.643 1.00 370.54 ? 178 PRO A CG    1 
ATOM   1330 C CD    . PRO A 1 178 ? 86.473  115.445 144.636 1.00 370.54 ? 178 PRO A CD    1 
ATOM   1331 N N     . TYR A 1 179 ? 88.905  118.046 145.641 1.00 118.71 ? 179 TYR A N     1 
ATOM   1332 C CA    . TYR A 1 179 ? 89.809  118.952 146.300 1.00 118.71 ? 179 TYR A CA    1 
ATOM   1333 C C     . TYR A 1 179 ? 91.244  118.541 145.997 1.00 118.71 ? 179 TYR A C     1 
ATOM   1334 O O     . TYR A 1 179 ? 92.068  119.371 145.597 1.00 118.71 ? 179 TYR A O     1 
ATOM   1335 C CB    . TYR A 1 179 ? 89.490  119.006 147.800 1.00 164.31 ? 179 TYR A CB    1 
ATOM   1336 C CG    . TYR A 1 179 ? 88.232  119.734 148.153 1.00 164.31 ? 179 TYR A CG    1 
ATOM   1337 C CD1   . TYR A 1 179 ? 87.096  119.575 147.424 1.00 164.31 ? 179 TYR A CD1   1 
ATOM   1338 C CD2   . TYR A 1 179 ? 88.195  120.600 149.215 1.00 164.31 ? 179 TYR A CD2   1 
ATOM   1339 C CE1   . TYR A 1 179 ? 85.946  120.244 147.731 1.00 164.31 ? 179 TYR A CE1   1 
ATOM   1340 C CE2   . TYR A 1 179 ? 87.052  121.281 149.543 1.00 164.31 ? 179 TYR A CE2   1 
ATOM   1341 C CZ    . TYR A 1 179 ? 85.922  121.101 148.795 1.00 164.31 ? 179 TYR A CZ    1 
ATOM   1342 O OH    . TYR A 1 179 ? 84.764  121.780 149.114 1.00 164.31 ? 179 TYR A OH    1 
ATOM   1343 N N     . ASN A 1 180 ? 91.547  117.262 146.126 1.00 115.22 ? 180 ASN A N     1 
ATOM   1344 C CA    . ASN A 1 180 ? 92.902  116.778 145.961 1.00 115.22 ? 180 ASN A CA    1 
ATOM   1345 C C     . ASN A 1 180 ? 93.385  117.000 144.554 1.00 115.22 ? 180 ASN A C     1 
ATOM   1346 O O     . ASN A 1 180 ? 94.549  117.350 144.323 1.00 115.22 ? 180 ASN A O     1 
ATOM   1347 C CB    . ASN A 1 180 ? 92.936  115.306 146.266 1.00 156.09 ? 180 ASN A CB    1 
ATOM   1348 C CG    . ASN A 1 180 ? 92.714  115.011 147.689 1.00 156.09 ? 180 ASN A CG    1 
ATOM   1349 O OD1   . ASN A 1 180 ? 92.949  115.835 148.547 1.00 156.09 ? 180 ASN A OD1   1 
ATOM   1350 N ND2   . ASN A 1 180 ? 92.261  113.811 147.966 1.00 156.09 ? 180 ASN A ND2   1 
ATOM   1351 N N     . ALA A 1 181 ? 92.477  116.861 143.610 1.00 111.50 ? 181 ALA A N     1 
ATOM   1352 C CA    . ALA A 1 181 ? 92.783  116.977 142.197 1.00 111.50 ? 181 ALA A CA    1 
ATOM   1353 C C     . ALA A 1 181 ? 93.267  118.364 141.816 1.00 111.50 ? 181 ALA A C     1 
ATOM   1354 O O     . ALA A 1 181 ? 94.121  118.508 140.936 1.00 111.50 ? 181 ALA A O     1 
ATOM   1355 C CB    . ALA A 1 181 ? 91.547  116.622 141.396 1.00 152.04 ? 181 ALA A CB    1 
ATOM   1356 N N     . ILE A 1 182 ? 92.753  119.397 142.458 1.00 106.82 ? 182 ILE A N     1 
ATOM   1357 C CA    . ILE A 1 182 ? 93.174  120.728 142.097 1.00 106.82 ? 182 ILE A CA    1 
ATOM   1358 C C     . ILE A 1 182 ? 94.383  121.118 142.853 1.00 106.82 ? 182 ILE A C     1 
ATOM   1359 O O     . ILE A 1 182 ? 95.242  121.808 142.321 1.00 106.82 ? 182 ILE A O     1 
ATOM   1360 C CB    . ILE A 1 182 ? 92.067  121.732 142.292 1.00 158.05 ? 182 ILE A CB    1 
ATOM   1361 C CG1   . ILE A 1 182 ? 91.056  121.440 141.239 1.00 158.05 ? 182 ILE A CG1   1 
ATOM   1362 C CG2   . ILE A 1 182 ? 92.594  123.169 142.215 1.00 158.05 ? 182 ILE A CG2   1 
ATOM   1363 C CD1   . ILE A 1 182 ? 89.841  122.193 141.378 1.00 158.05 ? 182 ILE A CD1   1 
ATOM   1364 N N     . MET A 1 183 ? 94.490  120.737 144.091 1.00 105.27 ? 183 MET A N     1 
ATOM   1365 C CA    . MET A 1 183 ? 95.696  121.144 144.762 1.00 105.27 ? 183 MET A CA    1 
ATOM   1366 C C     . MET A 1 183 ? 96.909  120.580 144.058 1.00 105.27 ? 183 MET A C     1 
ATOM   1367 O O     . MET A 1 183 ? 97.910  121.289 143.852 1.00 105.27 ? 183 MET A O     1 
ATOM   1368 C CB    . MET A 1 183 ? 95.666  120.709 146.194 1.00 151.18 ? 183 MET A CB    1 
ATOM   1369 C CG    . MET A 1 183 ? 94.598  121.354 146.998 1.00 151.18 ? 183 MET A CG    1 
ATOM   1370 S SD    . MET A 1 183 ? 94.705  123.115 147.009 1.00 151.18 ? 183 MET A SD    1 
ATOM   1371 C CE    . MET A 1 183 ? 96.154  123.400 147.983 1.00 151.18 ? 183 MET A CE    1 
ATOM   1372 N N     . THR A 1 184 ? 96.830  119.333 143.598 1.00 102.44 ? 184 THR A N     1 
ATOM   1373 C CA    . THR A 1 184 ? 98.009  118.845 142.919 1.00 102.44 ? 184 THR A CA    1 
ATOM   1374 C C     . THR A 1 184 ? 98.116  119.383 141.514 1.00 102.44 ? 184 THR A C     1 
ATOM   1375 O O     . THR A 1 184 ? 99.230  119.638 141.060 1.00 102.44 ? 184 THR A O     1 
ATOM   1376 C CB    . THR A 1 184 ? 98.100  117.341 142.918 1.00 143.40 ? 184 THR A CB    1 
ATOM   1377 O OG1   . THR A 1 184 ? 99.384  116.984 142.425 1.00 143.40 ? 184 THR A OG1   1 
ATOM   1378 C CG2   . THR A 1 184 ? 97.101  116.732 142.037 1.00 143.40 ? 184 THR A CG2   1 
ATOM   1379 N N     . LEU A 1 185 ? 97.006  119.608 140.815 1.00 95.76  ? 185 LEU A N     1 
ATOM   1380 C CA    . LEU A 1 185 ? 97.140  120.154 139.479 1.00 95.76  ? 185 LEU A CA    1 
ATOM   1381 C C     . LEU A 1 185 ? 97.818  121.485 139.550 1.00 95.76  ? 185 LEU A C     1 
ATOM   1382 O O     . LEU A 1 185 ? 98.660  121.803 138.714 1.00 95.76  ? 185 LEU A O     1 
ATOM   1383 C CB    . LEU A 1 185 ? 95.786  120.258 138.801 1.00 141.69 ? 185 LEU A CB    1 
ATOM   1384 C CG    . LEU A 1 185 ? 95.720  120.822 137.403 1.00 141.69 ? 185 LEU A CG    1 
ATOM   1385 C CD1   . LEU A 1 185 ? 96.573  120.028 136.446 1.00 141.69 ? 185 LEU A CD1   1 
ATOM   1386 C CD2   . LEU A 1 185 ? 94.292  120.802 136.936 1.00 141.69 ? 185 LEU A CD2   1 
ATOM   1387 N N     . SER A 1 186 ? 97.508  122.253 140.561 1.00 94.58  ? 186 SER A N     1 
ATOM   1388 C CA    . SER A 1 186 ? 98.137  123.533 140.716 1.00 94.58  ? 186 SER A CA    1 
ATOM   1389 C C     . SER A 1 186 ? 99.619  123.388 140.857 1.00 94.58  ? 186 SER A C     1 
ATOM   1390 O O     . SER A 1 186 ? 100.386 124.122 140.222 1.00 94.58  ? 186 SER A O     1 
ATOM   1391 C CB    . SER A 1 186 ? 97.576  124.218 141.922 1.00 127.39 ? 186 SER A CB    1 
ATOM   1392 O OG    . SER A 1 186 ? 98.174  125.467 142.100 1.00 127.39 ? 186 SER A OG    1 
ATOM   1393 N N     . ASN A 1 187 ? 100.059 122.444 141.663 1.00 92.29  ? 187 ASN A N     1 
ATOM   1394 C CA    . ASN A 1 187 ? 101.499 122.312 141.765 1.00 92.29  ? 187 ASN A CA    1 
ATOM   1395 C C     . ASN A 1 187 ? 102.119 121.784 140.487 1.00 92.29  ? 187 ASN A C     1 
ATOM   1396 O O     . ASN A 1 187 ? 103.252 122.139 140.171 1.00 92.29  ? 187 ASN A O     1 
ATOM   1397 C CB    . ASN A 1 187 ? 101.851 121.503 142.982 1.00 125.03 ? 187 ASN A CB    1 
ATOM   1398 C CG    . ASN A 1 187 ? 101.612 122.291 144.211 1.00 125.03 ? 187 ASN A CG    1 
ATOM   1399 O OD1   . ASN A 1 187 ? 101.619 123.515 144.161 1.00 125.03 ? 187 ASN A OD1   1 
ATOM   1400 N ND2   . ASN A 1 187 ? 101.383 121.641 145.306 1.00 125.03 ? 187 ASN A ND2   1 
ATOM   1401 N N     . LEU A 1 188 ? 101.413 120.970 139.722 1.00 91.44  ? 188 LEU A N     1 
ATOM   1402 C CA    . LEU A 1 188 ? 101.994 120.547 138.465 1.00 91.44  ? 188 LEU A CA    1 
ATOM   1403 C C     . LEU A 1 188 ? 102.178 121.741 137.551 1.00 91.44  ? 188 LEU A C     1 
ATOM   1404 O O     . LEU A 1 188 ? 103.213 121.877 136.891 1.00 91.44  ? 188 LEU A O     1 
ATOM   1405 C CB    . LEU A 1 188 ? 101.130 119.512 137.773 1.00 135.30 ? 188 LEU A CB    1 
ATOM   1406 C CG    . LEU A 1 188 ? 101.043 118.133 138.353 1.00 135.30 ? 188 LEU A CG    1 
ATOM   1407 C CD1   . LEU A 1 188 ? 99.904  117.359 137.677 1.00 135.30 ? 188 LEU A CD1   1 
ATOM   1408 C CD2   . LEU A 1 188 ? 102.349 117.425 138.150 1.00 135.30 ? 188 LEU A CD2   1 
ATOM   1409 N N     . ILE A 1 189 ? 101.203 122.643 137.540 1.00 87.60  ? 189 ILE A N     1 
ATOM   1410 C CA    . ILE A 1 189 ? 101.291 123.834 136.704 1.00 87.60  ? 189 ILE A CA    1 
ATOM   1411 C C     . ILE A 1 189 ? 102.473 124.669 137.116 1.00 87.60  ? 189 ILE A C     1 
ATOM   1412 O O     . ILE A 1 189 ? 103.185 125.185 136.272 1.00 87.60  ? 189 ILE A O     1 
ATOM   1413 C CB    . ILE A 1 189 ? 100.025 124.680 136.792 1.00 129.62 ? 189 ILE A CB    1 
ATOM   1414 C CG1   . ILE A 1 189 ? 98.850  123.947 136.235 1.00 129.62 ? 189 ILE A CG1   1 
ATOM   1415 C CG2   . ILE A 1 189 ? 100.231 125.872 136.065 1.00 129.62 ? 189 ILE A CG2   1 
ATOM   1416 C CD1   . ILE A 1 189 ? 97.515  124.541 136.574 1.00 129.62 ? 189 ILE A CD1   1 
ATOM   1417 N N     . LYS A 1 190 ? 102.690 124.819 138.415 1.00 85.02  ? 190 LYS A N     1 
ATOM   1418 C CA    . LYS A 1 190 ? 103.779 125.652 138.942 1.00 85.02  ? 190 LYS A CA    1 
ATOM   1419 C C     . LYS A 1 190 ? 105.165 125.033 138.799 1.00 85.02  ? 190 LYS A C     1 
ATOM   1420 O O     . LYS A 1 190 ? 106.123 125.762 138.559 1.00 85.02  ? 190 LYS A O     1 
ATOM   1421 C CB    . LYS A 1 190 ? 103.572 125.952 140.417 1.00 127.42 ? 190 LYS A CB    1 
ATOM   1422 C CG    . LYS A 1 190 ? 102.463 126.869 140.749 1.00 127.42 ? 190 LYS A CG    1 
ATOM   1423 C CD    . LYS A 1 190 ? 102.341 127.145 142.243 1.00 127.42 ? 190 LYS A CD    1 
ATOM   1424 C CE    . LYS A 1 190 ? 101.116 128.034 142.543 1.00 127.42 ? 190 LYS A CE    1 
ATOM   1425 N NZ    . LYS A 1 190 ? 100.938 128.383 143.996 1.00 127.42 ? 190 LYS A NZ    1 
ATOM   1426 N N     . TYR A 1 191 ? 105.329 123.732 138.968 1.00 87.75  ? 191 TYR A N     1 
ATOM   1427 C CA    . TYR A 1 191 ? 106.668 123.185 139.018 1.00 87.75  ? 191 TYR A CA    1 
ATOM   1428 C C     . TYR A 1 191 ? 107.123 122.180 137.946 1.00 87.75  ? 191 TYR A C     1 
ATOM   1429 O O     . TYR A 1 191 ? 108.325 121.995 137.814 1.00 87.75  ? 191 TYR A O     1 
ATOM   1430 C CB    . TYR A 1 191 ? 106.863 122.540 140.363 1.00 121.45 ? 191 TYR A CB    1 
ATOM   1431 C CG    . TYR A 1 191 ? 106.622 123.500 141.422 1.00 121.45 ? 191 TYR A CG    1 
ATOM   1432 C CD1   . TYR A 1 191 ? 107.485 124.506 141.633 1.00 121.45 ? 191 TYR A CD1   1 
ATOM   1433 C CD2   . TYR A 1 191 ? 105.540 123.401 142.221 1.00 121.45 ? 191 TYR A CD2   1 
ATOM   1434 C CE1   . TYR A 1 191 ? 107.276 125.401 142.600 1.00 121.45 ? 191 TYR A CE1   1 
ATOM   1435 C CE2   . TYR A 1 191 ? 105.323 124.303 143.190 1.00 121.45 ? 191 TYR A CE2   1 
ATOM   1436 C CZ    . TYR A 1 191 ? 106.206 125.304 143.369 1.00 121.45 ? 191 TYR A CZ    1 
ATOM   1437 O OH    . TYR A 1 191 ? 105.995 126.231 144.344 1.00 121.45 ? 191 TYR A OH    1 
ATOM   1438 N N     . ALA A 1 192 ? 106.256 121.471 137.246 1.00 85.67  ? 192 ALA A N     1 
ATOM   1439 C CA    . ALA A 1 192 ? 106.749 120.475 136.312 1.00 85.67  ? 192 ALA A CA    1 
ATOM   1440 C C     . ALA A 1 192 ? 107.159 121.149 135.013 1.00 85.67  ? 192 ALA A C     1 
ATOM   1441 O O     . ALA A 1 192 ? 106.681 122.232 134.704 1.00 85.67  ? 192 ALA A O     1 
ATOM   1442 C CB    . ALA A 1 192 ? 105.698 119.406 136.045 1.00 116.82 ? 192 ALA A CB    1 
ATOM   1443 N N     . SER A 1 193 ? 108.074 120.545 134.253 1.00 83.90  ? 193 SER A N     1 
ATOM   1444 C CA    . SER A 1 193 ? 108.387 121.107 132.947 1.00 83.90  ? 193 SER A CA    1 
ATOM   1445 C C     . SER A 1 193 ? 107.426 120.611 131.934 1.00 83.90  ? 193 SER A C     1 
ATOM   1446 O O     . SER A 1 193 ? 107.048 121.333 131.015 1.00 83.90  ? 193 SER A O     1 
ATOM   1447 C CB    . SER A 1 193 ? 109.770 120.736 132.481 1.00 113.01 ? 193 SER A CB    1 
ATOM   1448 O OG    . SER A 1 193 ? 110.772 121.245 133.321 1.00 113.01 ? 193 SER A OG    1 
ATOM   1449 N N     . CYS A 1 194 ? 107.011 119.383 132.123 1.00 86.48  ? 194 CYS A N     1 
ATOM   1450 C CA    . CYS A 1 194 ? 106.038 118.726 131.295 1.00 86.48  ? 194 CYS A CA    1 
ATOM   1451 C C     . CYS A 1 194 ? 105.267 117.736 132.110 1.00 86.48  ? 194 CYS A C     1 
ATOM   1452 O O     . CYS A 1 194 ? 105.753 117.223 133.120 1.00 86.48  ? 194 CYS A O     1 
ATOM   1453 C CB    . CYS A 1 194 ? 106.689 117.958 130.192 1.00 116.48 ? 194 CYS A CB    1 
ATOM   1454 S SG    . CYS A 1 194 ? 107.447 118.952 128.985 1.00 116.48 ? 194 CYS A SG    1 
ATOM   1455 N N     . SER A 1 195 ? 104.101 117.392 131.623 1.00 88.22  ? 195 SER A N     1 
ATOM   1456 C CA    . SER A 1 195 ? 103.378 116.353 132.296 1.00 88.22  ? 195 SER A CA    1 
ATOM   1457 C C     . SER A 1 195 ? 102.524 115.621 131.301 1.00 88.22  ? 195 SER A C     1 
ATOM   1458 O O     . SER A 1 195 ? 102.009 116.213 130.361 1.00 88.22  ? 195 SER A O     1 
ATOM   1459 C CB    . SER A 1 195 ? 102.552 116.924 133.379 1.00 118.82 ? 195 SER A CB    1 
ATOM   1460 O OG    . SER A 1 195 ? 101.618 117.786 132.847 1.00 118.82 ? 195 SER A OG    1 
ATOM   1461 N N     . ILE A 1 196 ? 102.355 114.340 131.513 1.00 91.21  ? 196 ILE A N     1 
ATOM   1462 C CA    . ILE A 1 196 ? 101.497 113.555 130.666 1.00 91.21  ? 196 ILE A CA    1 
ATOM   1463 C C     . ILE A 1 196 ? 100.228 113.329 131.413 1.00 91.21  ? 196 ILE A C     1 
ATOM   1464 O O     . ILE A 1 196 ? 100.223 112.782 132.512 1.00 91.21  ? 196 ILE A O     1 
ATOM   1465 C CB    . ILE A 1 196 ? 102.114 112.222 130.274 1.00 134.96 ? 196 ILE A CB    1 
ATOM   1466 C CG1   . ILE A 1 196 ? 103.507 112.396 129.706 1.00 134.96 ? 196 ILE A CG1   1 
ATOM   1467 C CG2   . ILE A 1 196 ? 101.192 111.513 129.326 1.00 134.96 ? 196 ILE A CG2   1 
ATOM   1468 C CD1   . ILE A 1 196 ? 103.628 113.274 128.503 1.00 134.96 ? 196 ILE A CD1   1 
ATOM   1469 N N     . VAL A 1 197 ? 99.148  113.758 130.833 1.00 97.20  ? 197 VAL A N     1 
ATOM   1470 C CA    . VAL A 1 197 ? 97.873  113.685 131.489 1.00 97.20  ? 197 VAL A CA    1 
ATOM   1471 C C     . VAL A 1 197 ? 97.237  112.410 131.075 1.00 97.20  ? 197 VAL A C     1 
ATOM   1472 O O     . VAL A 1 197 ? 96.793  112.281 129.936 1.00 97.20  ? 197 VAL A O     1 
ATOM   1473 C CB    . VAL A 1 197 ? 96.992  114.853 131.094 1.00 141.33 ? 197 VAL A CB    1 
ATOM   1474 C CG1   . VAL A 1 197 ? 95.628  114.720 131.696 1.00 141.33 ? 197 VAL A CG1   1 
ATOM   1475 C CG2   . VAL A 1 197 ? 97.654  116.143 131.525 1.00 141.33 ? 197 VAL A CG2   1 
ATOM   1476 N N     . LEU A 1 198 ? 97.153  111.487 131.988 1.00 103.66 ? 198 LEU A N     1 
ATOM   1477 C CA    . LEU A 1 198 ? 96.469  110.250 131.731 1.00 103.66 ? 198 LEU A CA    1 
ATOM   1478 C C     . LEU A 1 198 ? 95.330  110.227 132.704 1.00 103.66 ? 198 LEU A C     1 
ATOM   1479 O O     . LEU A 1 198 ? 95.429  110.833 133.761 1.00 103.66 ? 198 LEU A O     1 
ATOM   1480 C CB    . LEU A 1 198 ? 97.396  109.069 131.941 1.00 153.38 ? 198 LEU A CB    1 
ATOM   1481 C CG    . LEU A 1 198 ? 98.694  109.046 131.152 1.00 153.38 ? 198 LEU A CG    1 
ATOM   1482 C CD1   . LEU A 1 198 ? 99.513  107.884 131.587 1.00 153.38 ? 198 LEU A CD1   1 
ATOM   1483 C CD2   . LEU A 1 198 ? 98.403  108.920 129.673 1.00 153.38 ? 198 LEU A CD2   1 
ATOM   1484 N N     . ASP A 1 199 ? 94.250  109.558 132.387 1.00 109.98 ? 199 ASP A N     1 
ATOM   1485 C CA    . ASP A 1 199 ? 93.252  109.483 133.412 1.00 109.98 ? 199 ASP A CA    1 
ATOM   1486 C C     . ASP A 1 199 ? 92.539  108.188 133.299 1.00 109.98 ? 199 ASP A C     1 
ATOM   1487 O O     . ASP A 1 199 ? 92.599  107.513 132.278 1.00 109.98 ? 199 ASP A O     1 
ATOM   1488 C CB    . ASP A 1 199 ? 92.273  110.633 133.347 1.00 141.40 ? 199 ASP A CB    1 
ATOM   1489 C CG    . ASP A 1 199 ? 91.423  110.615 132.146 1.00 141.40 ? 199 ASP A CG    1 
ATOM   1490 O OD1   . ASP A 1 199 ? 90.568  109.731 132.027 1.00 141.40 ? 199 ASP A OD1   1 
ATOM   1491 O OD2   . ASP A 1 199 ? 91.562  111.535 131.336 1.00 141.40 ? 199 ASP A OD2   1 
ATOM   1492 N N     . ASN A 1 200 ? 91.841  107.855 134.330 1.00 110.89 ? 200 ASN A N     1 
ATOM   1493 C CA    . ASN A 1 200 ? 91.222  106.567 134.300 1.00 110.89 ? 200 ASN A CA    1 
ATOM   1494 C C     . ASN A 1 200 ? 89.878  106.542 133.638 1.00 110.89 ? 200 ASN A C     1 
ATOM   1495 O O     . ASN A 1 200 ? 89.343  105.457 133.460 1.00 110.89 ? 200 ASN A O     1 
ATOM   1496 C CB    . ASN A 1 200 ? 91.094  106.013 135.674 1.00 150.22 ? 200 ASN A CB    1 
ATOM   1497 C CG    . ASN A 1 200 ? 92.388  105.604 136.244 1.00 150.22 ? 200 ASN A CG    1 
ATOM   1498 O OD1   . ASN A 1 200 ? 93.323  105.227 135.549 1.00 150.22 ? 200 ASN A OD1   1 
ATOM   1499 N ND2   . ASN A 1 200 ? 92.465  105.668 137.528 1.00 150.22 ? 200 ASN A ND2   1 
ATOM   1500 N N     . GLU A 1 201 ? 89.323  107.662 133.233 1.00 109.98 ? 201 GLU A N     1 
ATOM   1501 C CA    . GLU A 1 201 ? 88.066  107.539 132.544 1.00 109.98 ? 201 GLU A CA    1 
ATOM   1502 C C     . GLU A 1 201 ? 88.332  107.045 131.157 1.00 109.98 ? 201 GLU A C     1 
ATOM   1503 O O     . GLU A 1 201 ? 87.659  106.136 130.651 1.00 109.98 ? 201 GLU A O     1 
ATOM   1504 C CB    . GLU A 1 201 ? 87.338  108.853 132.516 1.00 147.72 ? 201 GLU A CB    1 
ATOM   1505 C CG    . GLU A 1 201 ? 85.997  108.807 131.853 1.00 147.72 ? 201 GLU A CG    1 
ATOM   1506 C CD    . GLU A 1 201 ? 85.029  107.977 132.598 1.00 147.72 ? 201 GLU A CD    1 
ATOM   1507 O OE1   . GLU A 1 201 ? 85.287  107.675 133.756 1.00 147.72 ? 201 GLU A OE1   1 
ATOM   1508 O OE2   . GLU A 1 201 ? 83.988  107.627 132.034 1.00 147.72 ? 201 GLU A OE2   1 
ATOM   1509 N N     . ALA A 1 202 ? 89.362  107.587 130.556 1.00 105.05 ? 202 ALA A N     1 
ATOM   1510 C CA    . ALA A 1 202 ? 89.733  107.159 129.230 1.00 105.05 ? 202 ALA A CA    1 
ATOM   1511 C C     . ALA A 1 202 ? 90.329  105.778 129.240 1.00 105.05 ? 202 ALA A C     1 
ATOM   1512 O O     . ALA A 1 202 ? 90.022  104.972 128.376 1.00 105.05 ? 202 ALA A O     1 
ATOM   1513 C CB    . ALA A 1 202 ? 90.725  108.141 128.645 1.00 143.25 ? 202 ALA A CB    1 
ATOM   1514 N N     . LEU A 1 203 ? 91.182  105.484 130.190 1.00 105.96 ? 203 LEU A N     1 
ATOM   1515 C CA    . LEU A 1 203 ? 91.803  104.187 130.187 1.00 105.96 ? 203 LEU A CA    1 
ATOM   1516 C C     . LEU A 1 203 ? 90.774  103.125 130.408 1.00 105.96 ? 203 LEU A C     1 
ATOM   1517 O O     . LEU A 1 203 ? 90.864  102.038 129.838 1.00 105.96 ? 203 LEU A O     1 
ATOM   1518 C CB    . LEU A 1 203 ? 92.863  104.122 131.261 1.00 156.78 ? 203 LEU A CB    1 
ATOM   1519 C CG    . LEU A 1 203 ? 94.065  105.009 131.052 1.00 156.78 ? 203 LEU A CG    1 
ATOM   1520 C CD1   . LEU A 1 203 ? 94.812  105.059 132.316 1.00 156.78 ? 203 LEU A CD1   1 
ATOM   1521 C CD2   . LEU A 1 203 ? 94.940  104.456 129.976 1.00 156.78 ? 203 LEU A CD2   1 
ATOM   1522 N N     . PHE A 1 204 ? 89.795  103.416 131.239 1.00 107.54 ? 204 PHE A N     1 
ATOM   1523 C CA    . PHE A 1 204 ? 88.752  102.461 131.493 1.00 107.54 ? 204 PHE A CA    1 
ATOM   1524 C C     . PHE A 1 204 ? 87.967  102.167 130.244 1.00 107.54 ? 204 PHE A C     1 
ATOM   1525 O O     . PHE A 1 204 ? 87.728  100.995 129.922 1.00 107.54 ? 204 PHE A O     1 
ATOM   1526 C CB    . PHE A 1 204 ? 87.854  103.002 132.568 1.00 150.00 ? 204 PHE A CB    1 
ATOM   1527 C CG    . PHE A 1 204 ? 86.914  102.055 133.084 1.00 150.00 ? 204 PHE A CG    1 
ATOM   1528 C CD1   . PHE A 1 204 ? 87.273  101.250 134.099 1.00 150.00 ? 204 PHE A CD1   1 
ATOM   1529 C CD2   . PHE A 1 204 ? 85.652  101.998 132.598 1.00 150.00 ? 204 PHE A CD2   1 
ATOM   1530 C CE1   . PHE A 1 204 ? 86.410  100.375 134.620 1.00 150.00 ? 204 PHE A CE1   1 
ATOM   1531 C CE2   . PHE A 1 204 ? 84.772  101.130 133.106 1.00 150.00 ? 204 PHE A CE2   1 
ATOM   1532 C CZ    . PHE A 1 204 ? 85.147  100.308 134.128 1.00 150.00 ? 204 PHE A CZ    1 
ATOM   1533 N N     . SER A 1 205 ? 87.566  103.197 129.509 1.00 106.06 ? 205 SER A N     1 
ATOM   1534 C CA    . SER A 1 205 ? 86.814  102.910 128.299 1.00 106.06 ? 205 SER A CA    1 
ATOM   1535 C C     . SER A 1 205 ? 87.659  102.228 127.243 1.00 106.06 ? 205 SER A C     1 
ATOM   1536 O O     . SER A 1 205 ? 87.133  101.433 126.459 1.00 106.06 ? 205 SER A O     1 
ATOM   1537 C CB    . SER A 1 205 ? 86.226  104.176 127.721 1.00 142.85 ? 205 SER A CB    1 
ATOM   1538 O OG    . SER A 1 205 ? 87.233  104.952 127.126 1.00 142.85 ? 205 SER A OG    1 
ATOM   1539 N N     . ILE A 1 206 ? 88.963  102.491 127.208 1.00 105.15 ? 206 ILE A N     1 
ATOM   1540 C CA    . ILE A 1 206 ? 89.822  101.771 126.279 1.00 105.15 ? 206 ILE A CA    1 
ATOM   1541 C C     . ILE A 1 206 ? 89.832  100.317 126.646 1.00 105.15 ? 206 ILE A C     1 
ATOM   1542 O O     . ILE A 1 206 ? 89.732  99.447  125.782 1.00 105.15 ? 206 ILE A O     1 
ATOM   1543 C CB    . ILE A 1 206 ? 91.253  102.326 126.271 1.00 155.58 ? 206 ILE A CB    1 
ATOM   1544 C CG1   . ILE A 1 206 ? 91.279  103.711 125.698 1.00 155.58 ? 206 ILE A CG1   1 
ATOM   1545 C CG2   . ILE A 1 206 ? 92.165  101.412 125.503 1.00 155.58 ? 206 ILE A CG2   1 
ATOM   1546 C CD1   . ILE A 1 206 ? 92.593  104.480 125.917 1.00 155.58 ? 206 ILE A CD1   1 
ATOM   1547 N N     . ALA A 1 207 ? 89.968  100.019 127.920 1.00 106.81 ? 207 ALA A N     1 
ATOM   1548 C CA    . ALA A 1 207 ? 89.994  98.627  128.286 1.00 106.81 ? 207 ALA A CA    1 
ATOM   1549 C C     . ALA A 1 207 ? 88.706  97.952  127.881 1.00 106.81 ? 207 ALA A C     1 
ATOM   1550 O O     . ALA A 1 207 ? 88.730  96.861  127.307 1.00 106.81 ? 207 ALA A O     1 
ATOM   1551 C CB    . ALA A 1 207 ? 90.259  98.467  129.756 1.00 145.65 ? 207 ALA A CB    1 
ATOM   1552 N N     . GLU A 1 208 ? 87.584  98.619  128.065 1.00 112.22 ? 208 GLU A N     1 
ATOM   1553 C CA    . GLU A 1 208 ? 86.321  97.997  127.674 1.00 112.22 ? 208 GLU A CA    1 
ATOM   1554 C C     . GLU A 1 208 ? 86.194  97.788  126.171 1.00 112.22 ? 208 GLU A C     1 
ATOM   1555 O O     . GLU A 1 208 ? 85.671  96.759  125.736 1.00 112.22 ? 208 GLU A O     1 
ATOM   1556 C CB    . GLU A 1 208 ? 85.136  98.837  128.118 1.00 150.73 ? 208 GLU A CB    1 
ATOM   1557 C CG    . GLU A 1 208 ? 84.827  98.868  129.591 1.00 150.73 ? 208 GLU A CG    1 
ATOM   1558 C CD    . GLU A 1 208 ? 83.639  99.758  129.880 1.00 150.73 ? 208 GLU A CD    1 
ATOM   1559 O OE1   . GLU A 1 208 ? 83.344  100.609 129.040 1.00 150.73 ? 208 GLU A OE1   1 
ATOM   1560 O OE2   . GLU A 1 208 ? 82.981  99.592  130.910 1.00 150.73 ? 208 GLU A OE2   1 
ATOM   1561 N N     . LYS A 1 209 ? 86.621  98.754  125.352 1.00 110.74 ? 209 LYS A N     1 
ATOM   1562 C CA    . LYS A 1 209 ? 86.369  98.661  123.915 1.00 110.74 ? 209 LYS A CA    1 
ATOM   1563 C C     . LYS A 1 209 ? 87.518  98.138  123.063 1.00 110.74 ? 209 LYS A C     1 
ATOM   1564 O O     . LYS A 1 209 ? 87.271  97.573  122.000 1.00 110.74 ? 209 LYS A O     1 
ATOM   1565 C CB    . LYS A 1 209 ? 85.958  100.019 123.374 1.00 165.96 ? 209 LYS A CB    1 
ATOM   1566 C CG    . LYS A 1 209 ? 84.680  100.580 123.975 1.00 165.96 ? 209 LYS A CG    1 
ATOM   1567 C CD    . LYS A 1 209 ? 83.472  99.723  123.695 1.00 165.96 ? 209 LYS A CD    1 
ATOM   1568 C CE    . LYS A 1 209 ? 82.203  100.381 124.203 1.00 165.96 ? 209 LYS A CE    1 
ATOM   1569 N NZ    . LYS A 1 209 ? 80.993  99.532  123.980 1.00 165.96 ? 209 LYS A NZ    1 
ATOM   1570 N N     . LYS A 1 210 ? 88.755  98.310  123.461 1.00 108.63 ? 210 LYS A N     1 
ATOM   1571 C CA    . LYS A 1 210 ? 89.850  97.861  122.630 1.00 108.63 ? 210 LYS A CA    1 
ATOM   1572 C C     . LYS A 1 210 ? 90.540  96.629  123.182 1.00 108.63 ? 210 LYS A C     1 
ATOM   1573 O O     . LYS A 1 210 ? 91.000  95.796  122.412 1.00 108.63 ? 210 LYS A O     1 
ATOM   1574 C CB    . LYS A 1 210 ? 90.854  99.006  122.443 1.00 162.80 ? 210 LYS A CB    1 
ATOM   1575 C CG    . LYS A 1 210 ? 90.243  100.275 121.791 1.00 162.80 ? 210 LYS A CG    1 
ATOM   1576 C CD    . LYS A 1 210 ? 89.717  99.980  120.382 1.00 162.80 ? 210 LYS A CD    1 
ATOM   1577 C CE    . LYS A 1 210 ? 89.212  101.210 119.651 1.00 162.80 ? 210 LYS A CE    1 
ATOM   1578 N NZ    . LYS A 1 210 ? 88.694  100.844 118.293 1.00 162.80 ? 210 LYS A NZ    1 
ATOM   1579 N N     . LEU A 1 211 ? 90.600  96.462  124.483 1.00 107.47 ? 211 LEU A N     1 
ATOM   1580 C CA    . LEU A 1 211 ? 91.164  95.252  125.027 1.00 107.47 ? 211 LEU A CA    1 
ATOM   1581 C C     . LEU A 1 211 ? 90.100  94.227  125.299 1.00 107.47 ? 211 LEU A C     1 
ATOM   1582 O O     . LEU A 1 211 ? 90.396  93.132  125.766 1.00 107.47 ? 211 LEU A O     1 
ATOM   1583 C CB    . LEU A 1 211 ? 91.907  95.542  126.300 1.00 159.02 ? 211 LEU A CB    1 
ATOM   1584 C CG    . LEU A 1 211 ? 93.071  96.503  126.220 1.00 159.02 ? 211 LEU A CG    1 
ATOM   1585 C CD1   . LEU A 1 211 ? 93.619  96.702  127.617 1.00 159.02 ? 211 LEU A CD1   1 
ATOM   1586 C CD2   . LEU A 1 211 ? 94.161  95.960  125.320 1.00 159.02 ? 211 LEU A CD2   1 
ATOM   1587 N N     . GLU A 1 212 ? 88.861  94.577  125.024 1.00 113.09 ? 212 GLU A N     1 
ATOM   1588 C CA    . GLU A 1 212 ? 87.705  93.712  125.186 1.00 113.09 ? 212 GLU A CA    1 
ATOM   1589 C C     . GLU A 1 212 ? 87.581  93.137  126.581 1.00 113.09 ? 212 GLU A C     1 
ATOM   1590 O O     . GLU A 1 212 ? 87.338  91.954  126.755 1.00 113.09 ? 212 GLU A O     1 
ATOM   1591 C CB    . GLU A 1 212 ? 87.732  92.588  124.162 1.00 151.90 ? 212 GLU A CB    1 
ATOM   1592 C CG    . GLU A 1 212 ? 87.699  93.076  122.713 1.00 151.90 ? 212 GLU A CG    1 
ATOM   1593 C CD    . GLU A 1 212 ? 87.578  91.955  121.694 1.00 151.90 ? 212 GLU A CD    1 
ATOM   1594 O OE1   . GLU A 1 212 ? 87.684  90.785  122.066 1.00 151.90 ? 212 GLU A OE1   1 
ATOM   1595 O OE2   . GLU A 1 212 ? 87.372  92.253  120.514 1.00 151.90 ? 212 GLU A OE2   1 
ATOM   1596 N N     . VAL A 1 213 ? 87.710  93.970  127.580 1.00 115.39 ? 213 VAL A N     1 
ATOM   1597 C CA    . VAL A 1 213 ? 87.590  93.526  128.954 1.00 115.39 ? 213 VAL A CA    1 
ATOM   1598 C C     . VAL A 1 213 ? 86.215  93.929  129.461 1.00 115.39 ? 213 VAL A C     1 
ATOM   1599 O O     . VAL A 1 213 ? 85.876  95.114  129.459 1.00 115.39 ? 213 VAL A O     1 
ATOM   1600 C CB    . VAL A 1 213 ? 88.703  94.138  129.814 1.00 167.78 ? 213 VAL A CB    1 
ATOM   1601 C CG1   . VAL A 1 213 ? 88.594  93.686  131.234 1.00 167.78 ? 213 VAL A CG1   1 
ATOM   1602 C CG2   . VAL A 1 213 ? 90.029  93.760  129.248 1.00 167.78 ? 213 VAL A CG2   1 
ATOM   1603 N N     . GLU A 1 214 ? 85.428  92.966  129.930 1.00 120.03 ? 214 GLU A N     1 
ATOM   1604 C CA    . GLU A 1 214 ? 84.045  93.259  130.309 1.00 120.03 ? 214 GLU A CA    1 
ATOM   1605 C C     . GLU A 1 214 ? 83.948  94.241  131.457 1.00 120.03 ? 214 GLU A C     1 
ATOM   1606 O O     . GLU A 1 214 ? 83.039  95.073  131.506 1.00 120.03 ? 214 GLU A O     1 
ATOM   1607 C CB    . GLU A 1 214 ? 83.330  91.976  130.709 1.00 161.22 ? 214 GLU A CB    1 
ATOM   1608 C CG    . GLU A 1 214 ? 83.143  90.975  129.589 1.00 161.22 ? 214 GLU A CG    1 
ATOM   1609 C CD    . GLU A 1 214 ? 84.368  90.133  129.366 1.00 161.22 ? 214 GLU A CD    1 
ATOM   1610 O OE1   . GLU A 1 214 ? 85.357  90.332  130.079 1.00 161.22 ? 214 GLU A OE1   1 
ATOM   1611 O OE2   . GLU A 1 214 ? 84.343  89.273  128.486 1.00 161.22 ? 214 GLU A OE2   1 
ATOM   1612 N N     . ASN A 1 215 ? 84.846  94.123  132.421 1.00 113.44 ? 215 ASN A N     1 
ATOM   1613 C CA    . ASN A 1 215 ? 84.811  94.972  133.598 1.00 113.44 ? 215 ASN A CA    1 
ATOM   1614 C C     . ASN A 1 215 ? 86.223  95.199  134.043 1.00 113.44 ? 215 ASN A C     1 
ATOM   1615 O O     . ASN A 1 215 ? 86.745  94.470  134.884 1.00 113.44 ? 215 ASN A O     1 
ATOM   1616 C CB    . ASN A 1 215 ? 84.004  94.334  134.704 1.00 153.68 ? 215 ASN A CB    1 
ATOM   1617 C CG    . ASN A 1 215 ? 83.845  95.239  135.843 1.00 153.68 ? 215 ASN A CG    1 
ATOM   1618 O OD1   . ASN A 1 215 ? 84.182  96.419  135.759 1.00 153.68 ? 215 ASN A OD1   1 
ATOM   1619 N ND2   . ASN A 1 215 ? 83.319  94.722  136.935 1.00 153.68 ? 215 ASN A ND2   1 
ATOM   1620 N N     . PRO A 1 216 ? 86.877  96.200  133.492 1.00 110.76 ? 216 PRO A N     1 
ATOM   1621 C CA    . PRO A 1 216 ? 88.294  96.426  133.701 1.00 110.76 ? 216 PRO A CA    1 
ATOM   1622 C C     . PRO A 1 216 ? 88.651  96.529  135.154 1.00 110.76 ? 216 PRO A C     1 
ATOM   1623 O O     . PRO A 1 216 ? 88.005  97.219  135.926 1.00 110.76 ? 216 PRO A O     1 
ATOM   1624 C CB    . PRO A 1 216 ? 88.527  97.753  132.992 1.00 345.47 ? 216 PRO A CB    1 
ATOM   1625 C CG    . PRO A 1 216 ? 87.484  97.766  131.938 1.00 345.47 ? 216 PRO A CG    1 
ATOM   1626 C CD    . PRO A 1 216 ? 86.295  97.120  132.529 1.00 345.47 ? 216 PRO A CD    1 
ATOM   1627 N N     . SER A 1 217 ? 89.726  95.866  135.483 1.00 105.92 ? 217 SER A N     1 
ATOM   1628 C CA    . SER A 1 217 ? 90.283  95.845  136.802 1.00 105.92 ? 217 SER A CA    1 
ATOM   1629 C C     . SER A 1 217 ? 91.333  96.917  136.902 1.00 105.92 ? 217 SER A C     1 
ATOM   1630 O O     . SER A 1 217 ? 91.806  97.439  135.900 1.00 105.92 ? 217 SER A O     1 
ATOM   1631 C CB    . SER A 1 217 ? 90.890  94.490  137.071 1.00 142.66 ? 217 SER A CB    1 
ATOM   1632 O OG    . SER A 1 217 ? 92.000  94.289  136.233 1.00 142.66 ? 217 SER A OG    1 
ATOM   1633 N N     . LEU A 1 218 ? 91.744  97.219  138.120 1.00 106.56 ? 218 LEU A N     1 
ATOM   1634 C CA    . LEU A 1 218 ? 92.763  98.231  138.290 1.00 106.56 ? 218 LEU A CA    1 
ATOM   1635 C C     . LEU A 1 218 ? 94.028  97.818  137.560 1.00 106.56 ? 218 LEU A C     1 
ATOM   1636 O O     . LEU A 1 218 ? 94.751  98.658  137.001 1.00 106.56 ? 218 LEU A O     1 
ATOM   1637 C CB    . LEU A 1 218 ? 93.011  98.445  139.775 1.00 157.67 ? 218 LEU A CB    1 
ATOM   1638 C CG    . LEU A 1 218 ? 93.712  99.710  140.267 1.00 157.67 ? 218 LEU A CG    1 
ATOM   1639 C CD1   . LEU A 1 218 ? 92.928  100.939 139.904 1.00 157.67 ? 218 LEU A CD1   1 
ATOM   1640 C CD2   . LEU A 1 218 ? 93.864  99.617  141.760 1.00 157.67 ? 218 LEU A CD2   1 
ATOM   1641 N N     . GLU A 1 219 ? 94.269  96.520  137.489 1.00 106.64 ? 219 GLU A N     1 
ATOM   1642 C CA    . GLU A 1 219 ? 95.431  95.991  136.813 1.00 106.64 ? 219 GLU A CA    1 
ATOM   1643 C C     . GLU A 1 219 ? 95.369  96.129  135.300 1.00 106.64 ? 219 GLU A C     1 
ATOM   1644 O O     . GLU A 1 219 ? 96.423  96.142  134.652 1.00 106.64 ? 219 GLU A O     1 
ATOM   1645 C CB    . GLU A 1 219 ? 95.601  94.541  137.215 1.00 143.23 ? 219 GLU A CB    1 
ATOM   1646 C CG    . GLU A 1 219 ? 95.973  94.370  138.686 1.00 143.23 ? 219 GLU A CG    1 
ATOM   1647 C CD    . GLU A 1 219 ? 94.796  94.469  139.626 1.00 143.23 ? 219 GLU A CD    1 
ATOM   1648 O OE1   . GLU A 1 219 ? 93.662  94.566  139.155 1.00 143.23 ? 219 GLU A OE1   1 
ATOM   1649 O OE2   . GLU A 1 219 ? 95.007  94.457  140.840 1.00 143.23 ? 219 GLU A OE2   1 
ATOM   1650 N N     . ASP A 1 220 ? 94.187  96.263  134.706 1.00 105.21 ? 220 ASP A N     1 
ATOM   1651 C CA    . ASP A 1 220 ? 94.133  96.448  133.266 1.00 105.21 ? 220 ASP A CA    1 
ATOM   1652 C C     . ASP A 1 220 ? 94.428  97.889  132.941 1.00 105.21 ? 220 ASP A C     1 
ATOM   1653 O O     . ASP A 1 220 ? 95.038  98.213  131.916 1.00 105.21 ? 220 ASP A O     1 
ATOM   1654 C CB    . ASP A 1 220 ? 92.772  96.061  132.736 1.00 135.27 ? 220 ASP A CB    1 
ATOM   1655 C CG    . ASP A 1 220 ? 92.434  94.627  133.015 1.00 135.27 ? 220 ASP A CG    1 
ATOM   1656 O OD1   . ASP A 1 220 ? 93.234  93.759  132.671 1.00 135.27 ? 220 ASP A OD1   1 
ATOM   1657 O OD2   . ASP A 1 220 ? 91.365  94.368  133.597 1.00 135.27 ? 220 ASP A OD2   1 
ATOM   1658 N N     . LEU A 1 221 ? 94.020  98.759  133.835 1.00 104.76 ? 221 LEU A N     1 
ATOM   1659 C CA    . LEU A 1 221 ? 94.334  100.134 133.641 1.00 104.76 ? 221 LEU A CA    1 
ATOM   1660 C C     . LEU A 1 221 ? 95.832  100.284 133.706 1.00 104.76 ? 221 LEU A C     1 
ATOM   1661 O O     . LEU A 1 221 ? 96.435  100.962 132.867 1.00 104.76 ? 221 LEU A O     1 
ATOM   1662 C CB    . LEU A 1 221 ? 93.646  100.977 134.689 1.00 155.01 ? 221 LEU A CB    1 
ATOM   1663 C CG    . LEU A 1 221 ? 92.136  100.982 134.681 1.00 155.01 ? 221 LEU A CG    1 
ATOM   1664 C CD1   . LEU A 1 221 ? 91.627  101.642 135.919 1.00 155.01 ? 221 LEU A CD1   1 
ATOM   1665 C CD2   . LEU A 1 221 ? 91.632  101.723 133.524 1.00 155.01 ? 221 LEU A CD2   1 
ATOM   1666 N N     . ASN A 1 222 ? 96.459  99.586  134.642 1.00 104.15 ? 222 ASN A N     1 
ATOM   1667 C CA    . ASN A 1 222 ? 97.898  99.691  134.758 1.00 104.15 ? 222 ASN A CA    1 
ATOM   1668 C C     . ASN A 1 222 ? 98.598  99.089  133.576 1.00 104.15 ? 222 ASN A C     1 
ATOM   1669 O O     . ASN A 1 222 ? 99.650  99.574  133.186 1.00 104.15 ? 222 ASN A O     1 
ATOM   1670 C CB    . ASN A 1 222 ? 98.392  99.027  135.998 1.00 141.09 ? 222 ASN A CB    1 
ATOM   1671 C CG    . ASN A 1 222 ? 98.112  99.818  137.175 1.00 141.09 ? 222 ASN A CG    1 
ATOM   1672 O OD1   . ASN A 1 222 ? 97.842  101.003 137.084 1.00 141.09 ? 222 ASN A OD1   1 
ATOM   1673 N ND2   . ASN A 1 222 ? 98.170  99.185  138.321 1.00 141.09 ? 222 ASN A ND2   1 
ATOM   1674 N N     . LEU A 1 223 ? 98.030  98.062  132.980 1.00 101.17 ? 223 LEU A N     1 
ATOM   1675 C CA    . LEU A 1 223 ? 98.636  97.480  131.795 1.00 101.17 ? 223 LEU A CA    1 
ATOM   1676 C C     . LEU A 1 223 ? 98.727  98.494  130.676 1.00 101.17 ? 223 LEU A C     1 
ATOM   1677 O O     . LEU A 1 223 ? 99.785  98.654  130.051 1.00 101.17 ? 223 LEU A O     1 
ATOM   1678 C CB    . LEU A 1 223 ? 97.792  96.306  131.347 1.00 149.69 ? 223 LEU A CB    1 
ATOM   1679 C CG    . LEU A 1 223 ? 98.231  95.548  130.130 1.00 149.69 ? 223 LEU A CG    1 
ATOM   1680 C CD1   . LEU A 1 223 ? 99.537  94.846  130.416 1.00 149.69 ? 223 LEU A CD1   1 
ATOM   1681 C CD2   . LEU A 1 223 ? 97.134  94.588  129.763 1.00 149.69 ? 223 LEU A CD2   1 
ATOM   1682 N N     . ILE A 1 224 ? 97.622  99.203  130.410 1.00 100.06 ? 224 ILE A N     1 
ATOM   1683 C CA    . ILE A 1 224 ? 97.657  100.201 129.348 1.00 100.06 ? 224 ILE A CA    1 
ATOM   1684 C C     . ILE A 1 224 ? 98.646  101.287 129.697 1.00 100.06 ? 224 ILE A C     1 
ATOM   1685 O O     . ILE A 1 224 ? 99.399  101.757 128.841 1.00 100.06 ? 224 ILE A O     1 
ATOM   1686 C CB    . ILE A 1 224 ? 96.293  100.830 129.077 1.00 148.05 ? 224 ILE A CB    1 
ATOM   1687 C CG1   . ILE A 1 224 ? 95.315  99.809  128.592 1.00 148.05 ? 224 ILE A CG1   1 
ATOM   1688 C CG2   . ILE A 1 224 ? 96.450  101.944 128.041 1.00 148.05 ? 224 ILE A CG2   1 
ATOM   1689 C CD1   . ILE A 1 224 ? 93.884  100.289 128.597 1.00 148.05 ? 224 ILE A CD1   1 
ATOM   1690 N N     . ILE A 1 225 ? 98.640  101.722 130.940 1.00 96.58  ? 225 ILE A N     1 
ATOM   1691 C CA    . ILE A 1 225 ? 99.530  102.790 131.333 1.00 96.58  ? 225 ILE A CA    1 
ATOM   1692 C C     . ILE A 1 225 ? 100.950 102.378 131.145 1.00 96.58  ? 225 ILE A C     1 
ATOM   1693 O O     . ILE A 1 225 ? 101.775 103.164 130.681 1.00 96.58  ? 225 ILE A O     1 
ATOM   1694 C CB    . ILE A 1 225 ? 99.301  103.193 132.781 1.00 142.90 ? 225 ILE A CB    1 
ATOM   1695 C CG1   . ILE A 1 225 ? 97.963  103.825 132.947 1.00 142.90 ? 225 ILE A CG1   1 
ATOM   1696 C CG2   . ILE A 1 225 ? 100.336 104.192 133.176 1.00 142.90 ? 225 ILE A CG2   1 
ATOM   1697 C CD1   . ILE A 1 225 ? 97.516  103.924 134.397 1.00 142.90 ? 225 ILE A CD1   1 
ATOM   1698 N N     . ALA A 1 226 ? 101.279 101.169 131.537 1.00 93.29  ? 226 ALA A N     1 
ATOM   1699 C CA    . ALA A 1 226 ? 102.643 100.716 131.423 1.00 93.29  ? 226 ALA A CA    1 
ATOM   1700 C C     . ALA A 1 226 ? 103.079 100.739 129.994 1.00 93.29  ? 226 ALA A C     1 
ATOM   1701 O O     . ALA A 1 226 ? 104.209 101.138 129.694 1.00 93.29  ? 226 ALA A O     1 
ATOM   1702 C CB    . ALA A 1 226 ? 102.783 99.324  131.982 1.00 127.21 ? 226 ALA A CB    1 
ATOM   1703 N N     . GLN A 1 227 ? 102.195 100.342 129.089 1.00 93.92  ? 227 GLN A N     1 
ATOM   1704 C CA    . GLN A 1 227 ? 102.565 100.386 127.684 1.00 93.92  ? 227 GLN A CA    1 
ATOM   1705 C C     . GLN A 1 227 ? 102.826 101.805 127.227 1.00 93.92  ? 227 GLN A C     1 
ATOM   1706 O O     . GLN A 1 227 ? 103.778 102.045 126.476 1.00 93.92  ? 227 GLN A O     1 
ATOM   1707 C CB    . GLN A 1 227 ? 101.497 99.760  126.819 1.00 131.20 ? 227 GLN A CB    1 
ATOM   1708 C CG    . GLN A 1 227 ? 101.910 99.719  125.421 1.00 131.20 ? 227 GLN A CG    1 
ATOM   1709 C CD    . GLN A 1 227 ? 100.934 99.026  124.531 1.00 131.20 ? 227 GLN A CD    1 
ATOM   1710 O OE1   . GLN A 1 227 ? 100.000 98.362  124.986 1.00 131.20 ? 227 GLN A OE1   1 
ATOM   1711 N NE2   . GLN A 1 227 ? 101.141 99.176  123.234 1.00 131.20 ? 227 GLN A NE2   1 
ATOM   1712 N N     . VAL A 1 228 ? 102.024 102.772 127.680 1.00 90.99  ? 228 VAL A N     1 
ATOM   1713 C CA    . VAL A 1 228 ? 102.268 104.158 127.286 1.00 90.99  ? 228 VAL A CA    1 
ATOM   1714 C C     . VAL A 1 228 ? 103.587 104.635 127.809 1.00 90.99  ? 228 VAL A C     1 
ATOM   1715 O O     . VAL A 1 228 ? 104.383 105.203 127.075 1.00 90.99  ? 228 VAL A O     1 
ATOM   1716 C CB    . VAL A 1 228 ? 101.172 105.097 127.772 1.00 132.31 ? 228 VAL A CB    1 
ATOM   1717 C CG1   . VAL A 1 228 ? 101.558 106.514 127.503 1.00 132.31 ? 228 VAL A CG1   1 
ATOM   1718 C CG2   . VAL A 1 228 ? 99.876  104.775 127.111 1.00 132.31 ? 228 VAL A CG2   1 
ATOM   1719 N N     . LEU A 1 229 ? 103.863 104.408 129.071 1.00 91.70  ? 229 LEU A N     1 
ATOM   1720 C CA    . LEU A 1 229 ? 105.114 104.912 129.608 1.00 91.70  ? 229 LEU A CA    1 
ATOM   1721 C C     . LEU A 1 229 ? 106.297 104.284 128.918 1.00 91.70  ? 229 LEU A C     1 
ATOM   1722 O O     . LEU A 1 229 ? 107.279 104.961 128.630 1.00 91.70  ? 229 LEU A O     1 
ATOM   1723 C CB    . LEU A 1 229 ? 105.228 104.643 131.090 1.00 135.68 ? 229 LEU A CB    1 
ATOM   1724 C CG    . LEU A 1 229 ? 104.712 105.700 132.035 1.00 135.68 ? 229 LEU A CG    1 
ATOM   1725 C CD1   . LEU A 1 229 ? 103.249 105.996 131.750 1.00 135.68 ? 229 LEU A CD1   1 
ATOM   1726 C CD2   . LEU A 1 229 ? 104.884 105.205 133.439 1.00 135.68 ? 229 LEU A CD2   1 
ATOM   1727 N N     . THR A 1 230 ? 106.226 102.999 128.654 1.00 92.85  ? 230 THR A N     1 
ATOM   1728 C CA    . THR A 1 230 ? 107.344 102.317 128.043 1.00 92.85  ? 230 THR A CA    1 
ATOM   1729 C C     . THR A 1 230 ? 107.628 102.848 126.670 1.00 92.85  ? 230 THR A C     1 
ATOM   1730 O O     . THR A 1 230 ? 108.769 103.155 126.342 1.00 92.85  ? 230 THR A O     1 
ATOM   1731 C CB    . THR A 1 230 ? 107.063 100.839 127.951 1.00 129.97 ? 230 THR A CB    1 
ATOM   1732 O OG1   . THR A 1 230 ? 106.850 100.329 129.271 1.00 129.97 ? 230 THR A OG1   1 
ATOM   1733 C CG2   . THR A 1 230 ? 108.245 100.137 127.341 1.00 129.97 ? 230 THR A CG2   1 
ATOM   1734 N N     . ASN A 1 231 ? 106.599 102.980 125.858 1.00 90.13  ? 231 ASN A N     1 
ATOM   1735 C CA    . ASN A 1 231 ? 106.809 103.394 124.492 1.00 90.13  ? 231 ASN A CA    1 
ATOM   1736 C C     . ASN A 1 231 ? 107.078 104.887 124.353 1.00 90.13  ? 231 ASN A C     1 
ATOM   1737 O O     . ASN A 1 231 ? 107.747 105.300 123.405 1.00 90.13  ? 231 ASN A O     1 
ATOM   1738 C CB    . ASN A 1 231 ? 105.632 102.946 123.667 1.00 122.10 ? 231 ASN A CB    1 
ATOM   1739 C CG    . ASN A 1 231 ? 105.610 101.514 123.487 1.00 122.10 ? 231 ASN A CG    1 
ATOM   1740 O OD1   . ASN A 1 231 ? 106.645 100.846 123.419 1.00 122.10 ? 231 ASN A OD1   1 
ATOM   1741 N ND2   . ASN A 1 231 ? 104.440 100.987 123.394 1.00 122.10 ? 231 ASN A ND2   1 
ATOM   1742 N N     . VAL A 1 232 ? 106.578 105.703 125.272 1.00 86.22  ? 232 VAL A N     1 
ATOM   1743 C CA    . VAL A 1 232 ? 106.871 107.130 125.270 1.00 86.22  ? 232 VAL A CA    1 
ATOM   1744 C C     . VAL A 1 232 ? 108.291 107.361 125.675 1.00 86.22  ? 232 VAL A C     1 
ATOM   1745 O O     . VAL A 1 232 ? 109.019 108.121 125.041 1.00 86.22  ? 232 VAL A O     1 
ATOM   1746 C CB    . VAL A 1 232 ? 105.925 107.884 126.208 1.00 125.37 ? 232 VAL A CB    1 
ATOM   1747 C CG1   . VAL A 1 232 ? 106.365 109.293 126.394 1.00 125.37 ? 232 VAL A CG1   1 
ATOM   1748 C CG2   . VAL A 1 232 ? 104.523 107.890 125.628 1.00 125.37 ? 232 VAL A CG2   1 
ATOM   1749 N N     . THR A 1 233 ? 108.708 106.685 126.715 1.00 87.30  ? 233 THR A N     1 
ATOM   1750 C CA    . THR A 1 233 ? 110.047 106.836 127.231 1.00 87.30  ? 233 THR A CA    1 
ATOM   1751 C C     . THR A 1 233 ? 111.041 106.365 126.215 1.00 87.30  ? 233 THR A C     1 
ATOM   1752 O O     . THR A 1 233 ? 112.135 106.917 126.120 1.00 87.30  ? 233 THR A O     1 
ATOM   1753 C CB    . THR A 1 233 ? 110.194 106.076 128.539 1.00 122.20 ? 233 THR A CB    1 
ATOM   1754 O OG1   . THR A 1 233 ? 109.248 106.565 129.493 1.00 122.20 ? 233 THR A OG1   1 
ATOM   1755 C CG2   . THR A 1 233 ? 111.517 106.266 129.087 1.00 122.20 ? 233 THR A CG2   1 
ATOM   1756 N N     . ALA A 1 234 ? 110.660 105.389 125.401 1.00 92.89  ? 234 ALA A N     1 
ATOM   1757 C CA    . ALA A 1 234 ? 111.563 104.783 124.436 1.00 92.89  ? 234 ALA A CA    1 
ATOM   1758 C C     . ALA A 1 234 ? 112.221 105.774 123.500 1.00 92.89  ? 234 ALA A C     1 
ATOM   1759 O O     . ALA A 1 234 ? 113.358 105.550 123.090 1.00 92.89  ? 234 ALA A O     1 
ATOM   1760 C CB    . ALA A 1 234 ? 110.812 103.747 123.611 1.00 126.67 ? 234 ALA A CB    1 
ATOM   1761 N N     . SER A 1 235 ? 111.584 106.887 123.175 1.00 87.33  ? 235 SER A N     1 
ATOM   1762 C CA    . SER A 1 235 ? 112.205 107.823 122.239 1.00 87.33  ? 235 SER A CA    1 
ATOM   1763 C C     . SER A 1 235 ? 113.487 108.395 122.781 1.00 87.33  ? 235 SER A C     1 
ATOM   1764 O O     . SER A 1 235 ? 114.279 108.958 122.034 1.00 87.33  ? 235 SER A O     1 
ATOM   1765 C CB    . SER A 1 235 ? 111.274 108.973 121.959 1.00 117.63 ? 235 SER A CB    1 
ATOM   1766 O OG    . SER A 1 235 ? 111.226 109.835 123.063 1.00 117.63 ? 235 SER A OG    1 
ATOM   1767 N N     . LEU A 1 236 ? 113.683 108.293 124.074 1.00 86.57  ? 236 LEU A N     1 
ATOM   1768 C CA    . LEU A 1 236 ? 114.826 108.821 124.772 1.00 86.57  ? 236 LEU A CA    1 
ATOM   1769 C C     . LEU A 1 236 ? 115.940 107.840 124.895 1.00 86.57  ? 236 LEU A C     1 
ATOM   1770 O O     . LEU A 1 236 ? 117.064 108.253 125.182 1.00 86.57  ? 236 LEU A O     1 
ATOM   1771 C CB    . LEU A 1 236 ? 114.468 109.183 126.199 1.00 128.09 ? 236 LEU A CB    1 
ATOM   1772 C CG    . LEU A 1 236 ? 113.357 110.162 126.416 1.00 128.09 ? 236 LEU A CG    1 
ATOM   1773 C CD1   . LEU A 1 236 ? 113.026 110.180 127.871 1.00 128.09 ? 236 LEU A CD1   1 
ATOM   1774 C CD2   . LEU A 1 236 ? 113.793 111.522 125.957 1.00 128.09 ? 236 LEU A CD2   1 
ATOM   1775 N N     . ARG A 1 237 ? 115.669 106.562 124.749 1.00 86.82  ? 237 ARG A N     1 
ATOM   1776 C CA    . ARG A 1 237 ? 116.625 105.537 125.107 1.00 86.82  ? 237 ARG A CA    1 
ATOM   1777 C C     . ARG A 1 237 ? 117.061 104.502 124.094 1.00 86.82  ? 237 ARG A C     1 
ATOM   1778 O O     . ARG A 1 237 ? 117.946 103.718 124.423 1.00 86.82  ? 237 ARG A O     1 
ATOM   1779 C CB    . ARG A 1 237 ? 116.068 104.733 126.270 1.00 127.46 ? 237 ARG A CB    1 
ATOM   1780 C CG    . ARG A 1 237 ? 114.865 103.907 125.972 1.00 127.46 ? 237 ARG A CG    1 
ATOM   1781 C CD    . ARG A 1 237 ? 114.444 103.126 127.201 1.00 127.46 ? 237 ARG A CD    1 
ATOM   1782 N NE    . ARG A 1 237 ? 113.609 102.005 126.843 1.00 127.46 ? 237 ARG A NE    1 
ATOM   1783 C CZ    . ARG A 1 237 ? 112.299 102.048 126.822 1.00 127.46 ? 237 ARG A CZ    1 
ATOM   1784 N NH1   . ARG A 1 237 ? 111.652 103.139 127.171 1.00 127.46 ? 237 ARG A NH1   1 
ATOM   1785 N NH2   . ARG A 1 237 ? 111.619 100.974 126.448 1.00 127.46 ? 237 ARG A NH2   1 
ATOM   1786 N N     . PHE A 1 238 ? 116.450 104.412 122.943 1.00 86.47  ? 238 PHE A N     1 
ATOM   1787 C CA    . PHE A 1 238 ? 116.772 103.381 121.976 1.00 86.47  ? 238 PHE A CA    1 
ATOM   1788 C C     . PHE A 1 238 ? 117.009 104.043 120.647 1.00 86.47  ? 238 PHE A C     1 
ATOM   1789 O O     . PHE A 1 238 ? 116.163 103.973 119.771 1.00 86.47  ? 238 PHE A O     1 
ATOM   1790 C CB    . PHE A 1 238 ? 115.615 102.395 121.841 1.00 120.61 ? 238 PHE A CB    1 
ATOM   1791 C CG    . PHE A 1 238 ? 115.795 101.108 122.564 1.00 120.61 ? 238 PHE A CG    1 
ATOM   1792 C CD1   . PHE A 1 238 ? 116.831 100.278 122.263 1.00 120.61 ? 238 PHE A CD1   1 
ATOM   1793 C CD2   . PHE A 1 238 ? 114.901 100.720 123.543 1.00 120.61 ? 238 PHE A CD2   1 
ATOM   1794 C CE1   . PHE A 1 238 ? 117.007 99.088  122.937 1.00 120.61 ? 238 PHE A CE1   1 
ATOM   1795 C CE2   . PHE A 1 238 ? 115.055 99.530  124.215 1.00 120.61 ? 238 PHE A CE2   1 
ATOM   1796 C CZ    . PHE A 1 238 ? 116.113 98.707  123.913 1.00 120.61 ? 238 PHE A CZ    1 
ATOM   1797 N N     . SER A 1 239 ? 118.168 104.643 120.453 1.00 86.52  ? 239 SER A N     1 
ATOM   1798 C CA    . SER A 1 239 ? 118.539 105.136 119.127 1.00 86.52  ? 239 SER A CA    1 
ATOM   1799 C C     . SER A 1 239 ? 117.579 106.158 118.590 1.00 86.52  ? 239 SER A C     1 
ATOM   1800 O O     . SER A 1 239 ? 117.269 107.153 119.255 1.00 86.52  ? 239 SER A O     1 
ATOM   1801 C CB    . SER A 1 239 ? 118.618 103.991 118.171 1.00 116.53 ? 239 SER A CB    1 
ATOM   1802 O OG    . SER A 1 239 ? 119.048 104.454 116.898 1.00 116.53 ? 239 SER A OG    1 
ATOM   1803 N N     . GLY A 1 240 ? 117.126 105.957 117.385 1.00 86.28  ? 240 GLY A N     1 
ATOM   1804 C CA    . GLY A 1 240 ? 116.185 106.834 116.764 1.00 86.28  ? 240 GLY A CA    1 
ATOM   1805 C C     . GLY A 1 240 ? 116.822 107.881 115.879 1.00 86.28  ? 240 GLY A C     1 
ATOM   1806 O O     . GLY A 1 240 ? 117.957 108.285 116.058 1.00 86.28  ? 240 GLY A O     1 
ATOM   1807 N N     . THR A 1 241 ? 116.008 108.381 114.968 1.00 88.98  ? 241 THR A N     1 
ATOM   1808 C CA    . THR A 1 241 ? 116.385 109.378 113.991 1.00 88.98  ? 241 THR A CA    1 
ATOM   1809 C C     . THR A 1 241 ? 116.236 110.808 114.452 1.00 88.98  ? 241 THR A C     1 
ATOM   1810 O O     . THR A 1 241 ? 116.648 111.707 113.731 1.00 88.98  ? 241 THR A O     1 
ATOM   1811 C CB    . THR A 1 241 ? 115.538 109.228 112.730 1.00 124.56 ? 241 THR A CB    1 
ATOM   1812 O OG1   . THR A 1 241 ? 114.162 109.465 113.042 1.00 124.56 ? 241 THR A OG1   1 
ATOM   1813 C CG2   . THR A 1 241 ? 115.692 107.826 112.157 1.00 124.56 ? 241 THR A CG2   1 
ATOM   1814 N N     . LEU A 1 242 ? 115.659 111.074 115.609 1.00 83.62  ? 242 LEU A N     1 
ATOM   1815 C CA    . LEU A 1 242 ? 115.497 112.450 116.037 1.00 83.62  ? 242 LEU A CA    1 
ATOM   1816 C C     . LEU A 1 242 ? 116.399 112.874 117.206 1.00 83.62  ? 242 LEU A C     1 
ATOM   1817 O O     . LEU A 1 242 ? 116.406 114.048 117.554 1.00 83.62  ? 242 LEU A O     1 
ATOM   1818 C CB    . LEU A 1 242 ? 114.025 112.713 116.345 1.00 123.73 ? 242 LEU A CB    1 
ATOM   1819 C CG    . LEU A 1 242 ? 113.537 114.089 116.769 1.00 123.73 ? 242 LEU A CG    1 
ATOM   1820 C CD1   . LEU A 1 242 ? 113.905 115.113 115.759 1.00 123.73 ? 242 LEU A CD1   1 
ATOM   1821 C CD2   . LEU A 1 242 ? 112.031 114.063 116.942 1.00 123.73 ? 242 LEU A CD2   1 
ATOM   1822 N N     . ASN A 1 243 ? 117.180 111.977 117.806 1.00 86.05  ? 243 ASN A N     1 
ATOM   1823 C CA    . ASN A 1 243 ? 118.170 112.335 118.837 1.00 86.05  ? 243 ASN A CA    1 
ATOM   1824 C C     . ASN A 1 243 ? 117.626 113.121 120.025 1.00 86.05  ? 243 ASN A C     1 
ATOM   1825 O O     . ASN A 1 243 ? 118.205 114.123 120.431 1.00 86.05  ? 243 ASN A O     1 
ATOM   1826 C CB    . ASN A 1 243 ? 119.303 113.095 118.198 1.00 116.57 ? 243 ASN A CB    1 
ATOM   1827 C CG    . ASN A 1 243 ? 120.053 112.231 117.249 1.00 116.57 ? 243 ASN A CG    1 
ATOM   1828 O OD1   . ASN A 1 243 ? 120.294 111.068 117.559 1.00 116.57 ? 243 ASN A OD1   1 
ATOM   1829 N ND2   . ASN A 1 243 ? 120.402 112.752 116.076 1.00 116.57 ? 243 ASN A ND2   1 
ATOM   1830 N N     . LEU A 1 244 ? 116.541 112.640 120.624 1.00 83.45  ? 244 LEU A N     1 
ATOM   1831 C CA    . LEU A 1 244 ? 115.870 113.286 121.744 1.00 83.45  ? 244 LEU A CA    1 
ATOM   1832 C C     . LEU A 1 244 ? 116.467 112.991 123.110 1.00 83.45  ? 244 LEU A C     1 
ATOM   1833 O O     . LEU A 1 244 ? 117.113 111.979 123.338 1.00 83.45  ? 244 LEU A O     1 
ATOM   1834 C CB    . LEU A 1 244 ? 114.440 112.876 121.789 1.00 123.47 ? 244 LEU A CB    1 
ATOM   1835 C CG    . LEU A 1 244 ? 113.609 113.256 120.626 1.00 123.47 ? 244 LEU A CG    1 
ATOM   1836 C CD1   . LEU A 1 244 ? 112.312 112.586 120.788 1.00 123.47 ? 244 LEU A CD1   1 
ATOM   1837 C CD2   . LEU A 1 244 ? 113.412 114.754 120.593 1.00 123.47 ? 244 LEU A CD2   1 
ATOM   1838 N N     . ASP A 1 245 ? 116.171 113.889 124.037 1.00 90.31  ? 245 ASP A N     1 
ATOM   1839 C CA    . ASP A 1 245 ? 116.509 113.871 125.459 1.00 90.31  ? 245 ASP A CA    1 
ATOM   1840 C C     . ASP A 1 245 ? 115.339 114.526 126.173 1.00 90.31  ? 245 ASP A C     1 
ATOM   1841 O O     . ASP A 1 245 ? 114.406 115.002 125.518 1.00 90.31  ? 245 ASP A O     1 
ATOM   1842 C CB    . ASP A 1 245 ? 117.795 114.649 125.690 1.00 116.11 ? 245 ASP A CB    1 
ATOM   1843 C CG    . ASP A 1 245 ? 118.467 114.389 127.033 1.00 116.11 ? 245 ASP A CG    1 
ATOM   1844 O OD1   . ASP A 1 245 ? 117.800 113.996 127.993 1.00 116.11 ? 245 ASP A OD1   1 
ATOM   1845 O OD2   . ASP A 1 245 ? 119.678 114.638 127.127 1.00 116.11 ? 245 ASP A OD2   1 
ATOM   1846 N N     . LEU A 1 246 ? 115.360 114.603 127.497 1.00 87.97  ? 246 LEU A N     1 
ATOM   1847 C CA    . LEU A 1 246 ? 114.221 115.231 128.157 1.00 87.97  ? 246 LEU A CA    1 
ATOM   1848 C C     . LEU A 1 246 ? 114.223 116.728 127.939 1.00 87.97  ? 246 LEU A C     1 
ATOM   1849 O O     . LEU A 1 246 ? 113.162 117.337 127.748 1.00 87.97  ? 246 LEU A O     1 
ATOM   1850 C CB    . LEU A 1 246 ? 114.183 114.922 129.639 1.00 130.16 ? 246 LEU A CB    1 
ATOM   1851 C CG    . LEU A 1 246 ? 113.852 113.520 130.079 1.00 130.16 ? 246 LEU A CG    1 
ATOM   1852 C CD1   . LEU A 1 246 ? 114.029 113.403 131.576 1.00 130.16 ? 246 LEU A CD1   1 
ATOM   1853 C CD2   . LEU A 1 246 ? 112.463 113.144 129.723 1.00 130.16 ? 246 LEU A CD2   1 
ATOM   1854 N N     . GLY A 1 247 ? 115.394 117.346 127.956 1.00 87.79  ? 247 GLY A N     1 
ATOM   1855 C CA    . GLY A 1 247 ? 115.450 118.777 127.753 1.00 87.79  ? 247 GLY A CA    1 
ATOM   1856 C C     . GLY A 1 247 ? 114.965 119.140 126.374 1.00 87.79  ? 247 GLY A C     1 
ATOM   1857 O O     . GLY A 1 247 ? 114.292 120.157 126.169 1.00 87.79  ? 247 GLY A O     1 
ATOM   1858 N N     . LYS A 1 248 ? 115.280 118.289 125.417 1.00 87.14  ? 248 LYS A N     1 
ATOM   1859 C CA    . LYS A 1 248 ? 114.868 118.502 124.053 1.00 87.14  ? 248 LYS A CA    1 
ATOM   1860 C C     . LYS A 1 248 ? 113.373 118.324 123.902 1.00 87.14  ? 248 LYS A C     1 
ATOM   1861 O O     . LYS A 1 248 ? 112.747 119.095 123.186 1.00 87.14  ? 248 LYS A O     1 
ATOM   1862 C CB    . LYS A 1 248 ? 115.646 117.588 123.147 1.00 130.59 ? 248 LYS A CB    1 
ATOM   1863 C CG    . LYS A 1 248 ? 117.101 117.948 123.086 1.00 130.59 ? 248 LYS A CG    1 
ATOM   1864 C CD    . LYS A 1 248 ? 117.881 116.984 122.240 1.00 130.59 ? 248 LYS A CD    1 
ATOM   1865 C CE    . LYS A 1 248 ? 119.339 117.340 122.210 1.00 130.59 ? 248 LYS A CE    1 
ATOM   1866 N NZ    . LYS A 1 248 ? 120.106 116.375 121.414 1.00 130.59 ? 248 LYS A NZ    1 
ATOM   1867 N N     . LEU A 1 249 ? 112.767 117.369 124.604 1.00 82.77  ? 249 LEU A N     1 
ATOM   1868 C CA    . LEU A 1 249 ? 111.327 117.233 124.515 1.00 82.77  ? 249 LEU A CA    1 
ATOM   1869 C C     . LEU A 1 249 ? 110.646 118.458 125.042 1.00 82.77  ? 249 LEU A C     1 
ATOM   1870 O O     . LEU A 1 249 ? 109.615 118.868 124.507 1.00 82.77  ? 249 LEU A O     1 
ATOM   1871 C CB    . LEU A 1 249 ? 110.804 116.046 125.285 1.00 122.47 ? 249 LEU A CB    1 
ATOM   1872 C CG    . LEU A 1 249 ? 110.993 114.663 124.773 1.00 122.47 ? 249 LEU A CG    1 
ATOM   1873 C CD1   . LEU A 1 249 ? 110.561 113.704 125.833 1.00 122.47 ? 249 LEU A CD1   1 
ATOM   1874 C CD2   . LEU A 1 249 ? 110.161 114.476 123.550 1.00 122.47 ? 249 LEU A CD2   1 
ATOM   1875 N N     . VAL A 1 250 ? 111.165 119.046 126.114 1.00 82.82  ? 250 VAL A N     1 
ATOM   1876 C CA    . VAL A 1 250 ? 110.519 120.249 126.598 1.00 82.82  ? 250 VAL A CA    1 
ATOM   1877 C C     . VAL A 1 250 ? 110.587 121.294 125.522 1.00 82.82  ? 250 VAL A C     1 
ATOM   1878 O O     . VAL A 1 250 ? 109.591 121.929 125.185 1.00 82.82  ? 250 VAL A O     1 
ATOM   1879 C CB    . VAL A 1 250 ? 111.179 120.784 127.863 1.00 120.43 ? 250 VAL A CB    1 
ATOM   1880 C CG1   . VAL A 1 250 ? 110.527 122.057 128.255 1.00 120.43 ? 250 VAL A CG1   1 
ATOM   1881 C CG2   . VAL A 1 250 ? 111.093 119.807 128.971 1.00 120.43 ? 250 VAL A CG2   1 
ATOM   1882 N N     . THR A 1 251 ? 111.767 121.473 124.938 1.00 83.38  ? 251 THR A N     1 
ATOM   1883 C CA    . THR A 1 251 ? 111.896 122.485 123.904 1.00 83.38  ? 251 THR A CA    1 
ATOM   1884 C C     . THR A 1 251 ? 110.955 122.232 122.755 1.00 83.38  ? 251 THR A C     1 
ATOM   1885 O O     . THR A 1 251 ? 110.338 123.162 122.249 1.00 83.38  ? 251 THR A O     1 
ATOM   1886 C CB    . THR A 1 251 ? 113.314 122.565 123.385 1.00 116.72 ? 251 THR A CB    1 
ATOM   1887 O OG1   . THR A 1 251 ? 114.202 122.975 124.426 1.00 116.72 ? 251 THR A OG1   1 
ATOM   1888 C CG2   . THR A 1 251 ? 113.398 123.568 122.277 1.00 116.72 ? 251 THR A CG2   1 
ATOM   1889 N N     . ASN A 1 252 ? 110.814 120.998 122.319 1.00 82.15  ? 252 ASN A N     1 
ATOM   1890 C CA    . ASN A 1 252 ? 109.992 120.748 121.140 1.00 82.15  ? 252 ASN A CA    1 
ATOM   1891 C C     . ASN A 1 252 ? 108.496 120.798 121.416 1.00 82.15  ? 252 ASN A C     1 
ATOM   1892 O O     . ASN A 1 252 ? 107.735 121.258 120.572 1.00 82.15  ? 252 ASN A O     1 
ATOM   1893 C CB    . ASN A 1 252 ? 110.350 119.415 120.532 1.00 111.29 ? 252 ASN A CB    1 
ATOM   1894 C CG    . ASN A 1 252 ? 111.606 119.467 119.791 1.00 111.29 ? 252 ASN A CG    1 
ATOM   1895 O OD1   . ASN A 1 252 ? 112.065 120.545 119.393 1.00 111.29 ? 252 ASN A OD1   1 
ATOM   1896 N ND2   . ASN A 1 252 ? 112.204 118.319 119.595 1.00 111.29 ? 252 ASN A ND2   1 
ATOM   1897 N N     . LEU A 1 253 ? 108.042 120.312 122.558 1.00 75.38  ? 253 LEU A N     1 
ATOM   1898 C CA    . LEU A 1 253 ? 106.619 120.249 122.798 1.00 75.38  ? 253 LEU A CA    1 
ATOM   1899 C C     . LEU A 1 253 ? 106.058 121.361 123.674 1.00 75.38  ? 253 LEU A C     1 
ATOM   1900 O O     . LEU A 1 253 ? 104.846 121.491 123.744 1.00 75.38  ? 253 LEU A O     1 
ATOM   1901 C CB    . LEU A 1 253 ? 106.292 118.898 123.391 1.00 111.53 ? 253 LEU A CB    1 
ATOM   1902 C CG    . LEU A 1 253 ? 106.527 117.718 122.474 1.00 111.53 ? 253 LEU A CG    1 
ATOM   1903 C CD1   . LEU A 1 253 ? 106.301 116.462 123.255 1.00 111.53 ? 253 LEU A CD1   1 
ATOM   1904 C CD2   . LEU A 1 253 ? 105.549 117.740 121.314 1.00 111.53 ? 253 LEU A CD2   1 
ATOM   1905 N N     . VAL A 1 254 ? 106.848 122.184 124.332 1.00 74.79  ? 254 VAL A N     1 
ATOM   1906 C CA    . VAL A 1 254 ? 106.234 123.189 125.178 1.00 74.79  ? 254 VAL A CA    1 
ATOM   1907 C C     . VAL A 1 254 ? 106.489 124.606 124.705 1.00 74.79  ? 254 VAL A C     1 
ATOM   1908 O O     . VAL A 1 254 ? 107.491 125.198 125.061 1.00 74.79  ? 254 VAL A O     1 
ATOM   1909 C CB    . VAL A 1 254 ? 106.735 123.036 126.596 1.00 108.75 ? 254 VAL A CB    1 
ATOM   1910 C CG1   . VAL A 1 254 ? 106.105 124.038 127.489 1.00 108.75 ? 254 VAL A CG1   1 
ATOM   1911 C CG2   . VAL A 1 254 ? 106.447 121.677 127.071 1.00 108.75 ? 254 VAL A CG2   1 
ATOM   1912 N N     . PRO A 1 255 ? 105.602 125.178 123.912 1.00 78.27  ? 255 PRO A N     1 
ATOM   1913 C CA    . PRO A 1 255 ? 105.790 126.519 123.402 1.00 78.27  ? 255 PRO A CA    1 
ATOM   1914 C C     . PRO A 1 255 ? 105.633 127.579 124.438 1.00 78.27  ? 255 PRO A C     1 
ATOM   1915 O O     . PRO A 1 255 ? 106.189 128.669 124.290 1.00 78.27  ? 255 PRO A O     1 
ATOM   1916 C CB    . PRO A 1 255 ? 104.713 126.627 122.329 1.00 244.14 ? 255 PRO A CB    1 
ATOM   1917 C CG    . PRO A 1 255 ? 103.711 125.648 122.710 1.00 244.14 ? 255 PRO A CG    1 
ATOM   1918 C CD    . PRO A 1 255 ? 104.441 124.524 123.362 1.00 244.14 ? 255 PRO A CD    1 
ATOM   1919 N N     . PHE A 1 256 ? 104.933 127.316 125.493 1.00 82.61  ? 256 PHE A N     1 
ATOM   1920 C CA    . PHE A 1 256 ? 104.780 128.325 126.512 1.00 82.61  ? 256 PHE A CA    1 
ATOM   1921 C C     . PHE A 1 256 ? 104.945 127.662 127.846 1.00 82.61  ? 256 PHE A C     1 
ATOM   1922 O O     . PHE A 1 256 ? 104.507 126.534 128.043 1.00 82.61  ? 256 PHE A O     1 
ATOM   1923 C CB    . PHE A 1 256 ? 103.428 128.953 126.455 1.00 115.23 ? 256 PHE A CB    1 
ATOM   1924 C CG    . PHE A 1 256 ? 103.127 129.595 125.162 1.00 115.23 ? 256 PHE A CG    1 
ATOM   1925 C CD1   . PHE A 1 256 ? 103.469 130.862 124.941 1.00 115.23 ? 256 PHE A CD1   1 
ATOM   1926 C CD2   . PHE A 1 256 ? 102.497 128.913 124.181 1.00 115.23 ? 256 PHE A CD2   1 
ATOM   1927 C CE1   . PHE A 1 256 ? 103.209 131.449 123.770 1.00 115.23 ? 256 PHE A CE1   1 
ATOM   1928 C CE2   . PHE A 1 256 ? 102.234 129.491 122.994 1.00 115.23 ? 256 PHE A CE2   1 
ATOM   1929 C CZ    . PHE A 1 256 ? 102.597 130.763 122.788 1.00 115.23 ? 256 PHE A CZ    1 
ATOM   1930 N N     . SER A 1 257 ? 105.521 128.364 128.777 1.00 86.77  ? 257 SER A N     1 
ATOM   1931 C CA    . SER A 1 257 ? 105.512 127.749 130.062 1.00 86.77  ? 257 SER A CA    1 
ATOM   1932 C C     . SER A 1 257 ? 104.088 127.836 130.495 1.00 86.77  ? 257 SER A C     1 
ATOM   1933 O O     . SER A 1 257 ? 103.312 128.599 129.915 1.00 86.77  ? 257 SER A O     1 
ATOM   1934 C CB    . SER A 1 257 ? 106.436 128.474 131.016 1.00 116.87 ? 257 SER A CB    1 
ATOM   1935 O OG    . SER A 1 257 ? 105.922 129.748 131.305 1.00 116.87 ? 257 SER A OG    1 
ATOM   1936 N N     . ASN A 1 258 ? 103.708 127.025 131.457 1.00 87.61  ? 258 ASN A N     1 
ATOM   1937 C CA    . ASN A 1 258 ? 102.362 127.032 131.980 1.00 87.61  ? 258 ASN A CA    1 
ATOM   1938 C C     . ASN A 1 258 ? 101.349 126.396 131.043 1.00 87.61  ? 258 ASN A C     1 
ATOM   1939 O O     . ASN A 1 258 ? 100.178 126.353 131.386 1.00 87.61  ? 258 ASN A O     1 
ATOM   1940 C CB    . ASN A 1 258 ? 101.934 128.460 132.276 1.00 118.69 ? 258 ASN A CB    1 
ATOM   1941 C CG    . ASN A 1 258 ? 101.024 128.594 133.383 1.00 118.69 ? 258 ASN A CG    1 
ATOM   1942 O OD1   . ASN A 1 258 ? 101.260 128.107 134.472 1.00 118.69 ? 258 ASN A OD1   1 
ATOM   1943 N ND2   . ASN A 1 258 ? 99.949  129.299 133.142 1.00 118.69 ? 258 ASN A ND2   1 
ATOM   1944 N N     . LEU A 1 259 ? 101.748 125.872 129.891 1.00 84.10  ? 259 LEU A N     1 
ATOM   1945 C CA    . LEU A 1 259 ? 100.851 125.146 128.998 1.00 84.10  ? 259 LEU A CA    1 
ATOM   1946 C C     . LEU A 1 259 ? 101.470 123.833 128.573 1.00 84.10  ? 259 LEU A C     1 
ATOM   1947 O O     . LEU A 1 259 ? 101.334 123.401 127.439 1.00 84.10  ? 259 LEU A O     1 
ATOM   1948 C CB    . LEU A 1 259 ? 100.485 125.970 127.772 1.00 124.44 ? 259 LEU A CB    1 
ATOM   1949 C CG    . LEU A 1 259 ? 99.799  127.287 128.021 1.00 124.44 ? 259 LEU A CG    1 
ATOM   1950 C CD1   . LEU A 1 259 ? 99.659  127.963 126.763 1.00 124.44 ? 259 LEU A CD1   1 
ATOM   1951 C CD2   . LEU A 1 259 ? 98.433  127.110 128.620 1.00 124.44 ? 259 LEU A CD2   1 
ATOM   1952 N N     . HIS A 1 260 ? 102.116 123.163 129.495 1.00 84.63  ? 260 HIS A N     1 
ATOM   1953 C CA    . HIS A 1 260 ? 102.931 122.010 129.256 1.00 84.63  ? 260 HIS A CA    1 
ATOM   1954 C C     . HIS A 1 260 ? 102.246 120.688 129.467 1.00 84.63  ? 260 HIS A C     1 
ATOM   1955 O O     . HIS A 1 260 ? 102.923 119.656 129.536 1.00 84.63  ? 260 HIS A O     1 
ATOM   1956 C CB    . HIS A 1 260 ? 104.111 122.101 130.154 1.00 115.08 ? 260 HIS A CB    1 
ATOM   1957 C CG    . HIS A 1 260 ? 103.732 122.319 131.551 1.00 115.08 ? 260 HIS A CG    1 
ATOM   1958 N ND1   . HIS A 1 260 ? 103.061 123.444 131.934 1.00 115.08 ? 260 HIS A ND1   1 
ATOM   1959 C CD2   . HIS A 1 260 ? 103.927 121.595 132.666 1.00 115.08 ? 260 HIS A CD2   1 
ATOM   1960 C CE1   . HIS A 1 260 ? 102.854 123.405 133.231 1.00 115.08 ? 260 HIS A CE1   1 
ATOM   1961 N NE2   . HIS A 1 260 ? 103.370 122.288 133.700 1.00 115.08 ? 260 HIS A NE2   1 
ATOM   1962 N N     . PHE A 1 261 ? 100.947 120.675 129.548 1.00 88.16  ? 261 PHE A N     1 
ATOM   1963 C CA    . PHE A 1 261 ? 100.215 119.441 129.731 1.00 88.16  ? 261 PHE A CA    1 
ATOM   1964 C C     . PHE A 1 261 ? 100.036 118.740 128.413 1.00 88.16  ? 261 PHE A C     1 
ATOM   1965 O O     . PHE A 1 261 ? 99.428  119.296 127.507 1.00 88.16  ? 261 PHE A O     1 
ATOM   1966 C CB    . PHE A 1 261 ? 98.874  119.744 130.345 1.00 122.97 ? 261 PHE A CB    1 
ATOM   1967 C CG    . PHE A 1 261 ? 99.003  120.285 131.653 1.00 122.97 ? 261 PHE A CG    1 
ATOM   1968 C CD1   . PHE A 1 261 ? 99.136  119.460 132.694 1.00 122.97 ? 261 PHE A CD1   1 
ATOM   1969 C CD2   . PHE A 1 261 ? 99.093  121.593 131.836 1.00 122.97 ? 261 PHE A CD2   1 
ATOM   1970 C CE1   . PHE A 1 261 ? 99.321  119.931 133.911 1.00 122.97 ? 261 PHE A CE1   1 
ATOM   1971 C CE2   . PHE A 1 261 ? 99.284  122.081 133.039 1.00 122.97 ? 261 PHE A CE2   1 
ATOM   1972 C CZ    . PHE A 1 261 ? 99.401  121.247 134.093 1.00 122.97 ? 261 PHE A CZ    1 
ATOM   1973 N N     . LEU A 1 262 ? 100.493 117.508 128.314 1.00 85.49  ? 262 LEU A N     1 
ATOM   1974 C CA    . LEU A 1 262 ? 100.480 116.752 127.086 1.00 85.49  ? 262 LEU A CA    1 
ATOM   1975 C C     . LEU A 1 262 ? 99.575  115.538 127.120 1.00 85.49  ? 262 LEU A C     1 
ATOM   1976 O O     . LEU A 1 262 ? 99.455  114.852 128.124 1.00 85.49  ? 262 LEU A O     1 
ATOM   1977 C CB    . LEU A 1 262 ? 101.872 116.261 126.768 1.00 126.49 ? 262 LEU A CB    1 
ATOM   1978 C CG    . LEU A 1 262 ? 102.975 117.269 126.598 1.00 126.49 ? 262 LEU A CG    1 
ATOM   1979 C CD1   . LEU A 1 262 ? 104.278 116.606 126.504 1.00 126.49 ? 262 LEU A CD1   1 
ATOM   1980 C CD2   . LEU A 1 262 ? 102.739 118.045 125.372 1.00 126.49 ? 262 LEU A CD2   1 
ATOM   1981 N N     . MET A 1 263 ? 98.983  115.241 125.986 1.00 88.04  ? 263 MET A N     1 
ATOM   1982 C CA    . MET A 1 263 ? 98.222  114.038 125.771 1.00 88.04  ? 263 MET A CA    1 
ATOM   1983 C C     . MET A 1 263 ? 99.140  112.955 125.292 1.00 88.04  ? 263 MET A C     1 
ATOM   1984 O O     . MET A 1 263 ? 100.151 113.233 124.649 1.00 88.04  ? 263 MET A O     1 
ATOM   1985 C CB    . MET A 1 263 ? 97.183  114.227 124.693 1.00 126.44 ? 263 MET A CB    1 
ATOM   1986 C CG    . MET A 1 263 ? 96.126  115.140 124.993 1.00 126.44 ? 263 MET A CG    1 
ATOM   1987 S SD    . MET A 1 263 ? 94.994  115.190 123.647 1.00 126.44 ? 263 MET A SD    1 
ATOM   1988 C CE    . MET A 1 263 ? 93.850  116.426 124.240 1.00 126.44 ? 263 MET A CE    1 
ATOM   1989 N N     . ALA A 1 264 ? 98.768  111.715 125.527 1.00 90.81  ? 264 ALA A N     1 
ATOM   1990 C CA    . ALA A 1 264 ? 99.531  110.617 124.974 1.00 90.81  ? 264 ALA A CA    1 
ATOM   1991 C C     . ALA A 1 264 ? 98.599  109.564 124.442 1.00 90.81  ? 264 ALA A C     1 
ATOM   1992 O O     . ALA A 1 264 ? 97.539  109.314 125.015 1.00 90.81  ? 264 ALA A O     1 
ATOM   1993 C CB    . ALA A 1 264 ? 100.441 110.000 126.012 1.00 123.83 ? 264 ALA A CB    1 
ATOM   1994 N N     . SER A 1 265 ? 99.024  108.930 123.366 1.00 90.24  ? 265 SER A N     1 
ATOM   1995 C CA    . SER A 1 265 ? 98.278  107.888 122.690 1.00 90.24  ? 265 SER A CA    1 
ATOM   1996 C C     . SER A 1 265 ? 99.184  106.847 122.092 1.00 90.24  ? 265 SER A C     1 
ATOM   1997 O O     . SER A 1 265 ? 100.147 107.191 121.415 1.00 90.24  ? 265 SER A O     1 
ATOM   1998 C CB    . SER A 1 265 ? 97.459  108.491 121.585 1.00 121.55 ? 265 SER A CB    1 
ATOM   1999 O OG    . SER A 1 265 ? 96.767  107.499 120.874 1.00 121.55 ? 265 SER A OG    1 
ATOM   2000 N N     . THR A 1 266 ? 98.879  105.586 122.285 1.00 88.65  ? 266 THR A N     1 
ATOM   2001 C CA    . THR A 1 266 ? 99.693  104.548 121.690 1.00 88.65  ? 266 THR A CA    1 
ATOM   2002 C C     . THR A 1 266 ? 98.844  103.463 121.097 1.00 88.65  ? 266 THR A C     1 
ATOM   2003 O O     . THR A 1 266 ? 97.768  103.167 121.581 1.00 88.65  ? 266 THR A O     1 
ATOM   2004 C CB    . THR A 1 266 ? 100.597 103.868 122.665 1.00 124.09 ? 266 THR A CB    1 
ATOM   2005 O OG1   . THR A 1 266 ? 99.799  103.213 123.648 1.00 124.09 ? 266 THR A OG1   1 
ATOM   2006 C CG2   . THR A 1 266 ? 101.529 104.845 123.341 1.00 124.09 ? 266 THR A CG2   1 
ATOM   2007 N N     . ALA A 1 267 ? 99.410  102.779 120.131 1.00 82.87  ? 267 ALA A N     1 
ATOM   2008 C CA    . ALA A 1 267 ? 98.770  101.617 119.571 1.00 82.87  ? 267 ALA A CA    1 
ATOM   2009 C C     . ALA A 1 267 ? 99.832  100.774 118.904 1.00 82.87  ? 267 ALA A C     1 
ATOM   2010 O O     . ALA A 1 267 ? 100.886 101.288 118.561 1.00 82.87  ? 267 ALA A O     1 
ATOM   2011 C CB    . ALA A 1 267 ? 97.687  102.036 118.583 1.00 113.00 ? 267 ALA A CB    1 
ATOM   2012 N N     . PRO A 1 268 ? 99.607  99.489  118.726 1.00 86.32  ? 268 PRO A N     1 
ATOM   2013 C CA    . PRO A 1 268 ? 98.512  98.638  119.100 1.00 86.32  ? 268 PRO A CA    1 
ATOM   2014 C C     . PRO A 1 268 ? 98.571  98.364  120.545 1.00 86.32  ? 268 PRO A C     1 
ATOM   2015 O O     . PRO A 1 268 ? 99.644  98.441  121.109 1.00 86.32  ? 268 PRO A O     1 
ATOM   2016 C CB    . PRO A 1 268 ? 98.786  97.370  118.324 1.00 269.23 ? 268 PRO A CB    1 
ATOM   2017 C CG    . PRO A 1 268 ? 100.223 97.344  118.224 1.00 269.23 ? 268 PRO A CG    1 
ATOM   2018 C CD    . PRO A 1 268 ? 100.639 98.740  118.053 1.00 269.23 ? 268 PRO A CD    1 
ATOM   2019 N N     . LEU A 1 269 ? 97.452  98.022  121.160 1.00 96.97  ? 269 LEU A N     1 
ATOM   2020 C CA    . LEU A 1 269 ? 97.444  97.591  122.534 1.00 96.97  ? 269 LEU A CA    1 
ATOM   2021 C C     . LEU A 1 269 ? 97.199  96.095  122.545 1.00 96.97  ? 269 LEU A C     1 
ATOM   2022 O O     . LEU A 1 269 ? 96.521  95.558  121.674 1.00 96.97  ? 269 LEU A O     1 
ATOM   2023 C CB    . LEU A 1 269 ? 96.369  98.315  123.332 1.00 143.48 ? 269 LEU A CB    1 
ATOM   2024 C CG    . LEU A 1 269 ? 96.352  99.830  123.305 1.00 143.48 ? 269 LEU A CG    1 
ATOM   2025 C CD1   . LEU A 1 269 ? 95.190  100.315 124.132 1.00 143.48 ? 269 LEU A CD1   1 
ATOM   2026 C CD2   . LEU A 1 269 ? 97.650  100.392 123.818 1.00 143.48 ? 269 LEU A CD2   1 
ATOM   2027 N N     . VAL A 1 270 ? 97.746  95.424  123.538 1.00 108.51 ? 270 VAL A N     1 
ATOM   2028 C CA    . VAL A 1 270 ? 97.664  93.978  123.665 1.00 108.51 ? 270 VAL A CA    1 
ATOM   2029 C C     . VAL A 1 270 ? 97.228  93.602  125.084 1.00 108.51 ? 270 VAL A C     1 
ATOM   2030 O O     . VAL A 1 270 ? 97.813  94.094  126.049 1.00 108.51 ? 270 VAL A O     1 
ATOM   2031 C CB    . VAL A 1 270 ? 99.048  93.391  123.365 1.00 157.78 ? 270 VAL A CB    1 
ATOM   2032 C CG1   . VAL A 1 270 ? 99.042  91.928  123.538 1.00 157.78 ? 270 VAL A CG1   1 
ATOM   2033 C CG2   . VAL A 1 270 ? 99.483  93.769  121.950 1.00 157.78 ? 270 VAL A CG2   1 
ATOM   2034 N N     . LEU A 1 271 ? 96.252  92.693  125.244 1.00 115.40 ? 271 LEU A N     1 
ATOM   2035 C CA    . LEU A 1 271 ? 95.800  92.379  126.618 1.00 115.40 ? 271 LEU A CA    1 
ATOM   2036 C C     . LEU A 1 271 ? 96.659  91.315  127.304 1.00 115.40 ? 271 LEU A C     1 
ATOM   2037 O O     . LEU A 1 271 ? 96.219  90.199  127.581 1.00 115.40 ? 271 LEU A O     1 
ATOM   2038 C CB    . LEU A 1 271 ? 94.343  91.932  126.668 1.00 170.75 ? 271 LEU A CB    1 
ATOM   2039 C CG    . LEU A 1 271 ? 93.692  91.695  128.078 1.00 170.75 ? 271 LEU A CG    1 
ATOM   2040 C CD1   . LEU A 1 271 ? 93.681  92.949  128.947 1.00 170.75 ? 271 LEU A CD1   1 
ATOM   2041 C CD2   . LEU A 1 271 ? 92.279  91.180  127.906 1.00 170.75 ? 271 LEU A CD2   1 
ATOM   2042 N N     . ALA A 1 272 ? 97.888  91.703  127.631 1.00 119.49 ? 272 ALA A N     1 
ATOM   2043 C CA    . ALA A 1 272 ? 98.801  90.888  128.438 1.00 119.49 ? 272 ALA A CA    1 
ATOM   2044 C C     . ALA A 1 272 ? 98.972  89.459  127.926 1.00 119.49 ? 272 ALA A C     1 
ATOM   2045 O O     . ALA A 1 272 ? 98.924  88.504  128.699 1.00 119.49 ? 272 ALA A O     1 
ATOM   2046 C CB    . ALA A 1 272 ? 98.335  90.852  129.890 1.00 162.94 ? 272 ALA A CB    1 
ATOM   2047 N N     . GLY A 1 273 ? 99.205  89.304  126.632 1.00 120.93 ? 273 GLY A N     1 
ATOM   2048 C CA    . GLY A 1 273 ? 99.398  87.978  126.066 1.00 120.93 ? 273 GLY A CA    1 
ATOM   2049 C C     . GLY A 1 273 ? 99.678  88.113  124.589 1.00 120.93 ? 273 GLY A C     1 
ATOM   2050 O O     . GLY A 1 273 ? 99.638  89.203  124.037 1.00 120.93 ? 273 GLY A O     1 
ATOM   2051 N N     . LYS A 1 274 ? 99.953  87.001  123.919 1.00 123.69 ? 274 LYS A N     1 
ATOM   2052 C CA    . LYS A 1 274 ? 100.324 87.126  122.506 1.00 123.69 ? 274 LYS A CA    1 
ATOM   2053 C C     . LYS A 1 274 ? 99.087  87.162  121.608 1.00 123.69 ? 274 LYS A C     1 
ATOM   2054 O O     . LYS A 1 274 ? 98.778  86.225  120.871 1.00 123.69 ? 274 LYS A O     1 
ATOM   2055 C CB    . LYS A 1 274 ? 101.287 86.019  122.104 1.00 185.37 ? 274 LYS A CB    1 
ATOM   2056 C CG    . LYS A 1 274 ? 102.626 86.041  122.884 1.00 185.37 ? 274 LYS A CG    1 
ATOM   2057 C CD    . LYS A 1 274 ? 103.443 87.335  122.635 1.00 185.37 ? 274 LYS A CD    1 
ATOM   2058 C CE    . LYS A 1 274 ? 104.808 87.308  123.330 1.00 185.37 ? 274 LYS A CE    1 
ATOM   2059 N NZ    . LYS A 1 274 ? 105.582 88.576  123.110 1.00 185.37 ? 274 LYS A NZ    1 
ATOM   2060 N N     . GLU A 1 275 ? 98.387  88.293  121.678 1.00 125.93 ? 275 GLU A N     1 
ATOM   2061 C CA    . GLU A 1 275 ? 97.188  88.553  120.890 1.00 125.93 ? 275 GLU A CA    1 
ATOM   2062 C C     . GLU A 1 275 ? 97.524  89.232  119.585 1.00 125.93 ? 275 GLU A C     1 
ATOM   2063 O O     . GLU A 1 275 ? 96.658  89.366  118.713 1.00 125.93 ? 275 GLU A O     1 
ATOM   2064 C CB    . GLU A 1 275 ? 96.217  89.458  121.651 1.00 169.14 ? 275 GLU A CB    1 
ATOM   2065 C CG    . GLU A 1 275 ? 95.675  88.907  122.935 1.00 169.14 ? 275 GLU A CG    1 
ATOM   2066 C CD    . GLU A 1 275 ? 94.671  89.844  123.544 1.00 169.14 ? 275 GLU A CD    1 
ATOM   2067 O OE1   . GLU A 1 275 ? 94.738  91.057  123.278 1.00 169.14 ? 275 GLU A OE1   1 
ATOM   2068 O OE2   . GLU A 1 275 ? 93.795  89.357  124.258 1.00 169.14 ? 275 GLU A OE2   1 
ATOM   2069 N N     . SER A 1 276 ? 98.755  89.699  119.482 1.00 121.10 ? 276 SER A N     1 
ATOM   2070 C CA    . SER A 1 276 ? 99.220  90.450  118.343 1.00 121.10 ? 276 SER A CA    1 
ATOM   2071 C C     . SER A 1 276 ? 99.185  89.582  117.107 1.00 121.10 ? 276 SER A C     1 
ATOM   2072 O O     . SER A 1 276 ? 99.415  88.374  117.175 1.00 121.10 ? 276 SER A O     1 
ATOM   2073 C CB    . SER A 1 276 ? 100.642 90.910  118.600 1.00 163.11 ? 276 SER A CB    1 
ATOM   2074 O OG    . SER A 1 276 ? 100.705 91.746  119.730 1.00 163.11 ? 276 SER A OG    1 
ATOM   2075 N N     . TYR A 1 277 ? 98.921  90.204  115.960 1.00 113.27 ? 277 TYR A N     1 
ATOM   2076 C CA    . TYR A 1 277 ? 98.874  89.438  114.731 1.00 113.27 ? 277 TYR A CA    1 
ATOM   2077 C C     . TYR A 1 277 ? 99.331  90.255  113.534 1.00 113.27 ? 277 TYR A C     1 
ATOM   2078 O O     . TYR A 1 277 ? 99.219  91.481  113.504 1.00 113.27 ? 277 TYR A O     1 
ATOM   2079 C CB    . TYR A 1 277 ? 97.467  88.920  114.495 1.00 156.78 ? 277 TYR A CB    1 
ATOM   2080 C CG    . TYR A 1 277 ? 96.468  90.026  114.364 1.00 156.78 ? 277 TYR A CG    1 
ATOM   2081 C CD1   . TYR A 1 277 ? 95.869  90.568  115.488 1.00 156.78 ? 277 TYR A CD1   1 
ATOM   2082 C CD2   . TYR A 1 277 ? 96.129  90.534  113.119 1.00 156.78 ? 277 TYR A CD2   1 
ATOM   2083 C CE1   . TYR A 1 277 ? 94.957  91.587  115.382 1.00 156.78 ? 277 TYR A CE1   1 
ATOM   2084 C CE2   . TYR A 1 277 ? 95.218  91.555  113.001 1.00 156.78 ? 277 TYR A CE2   1 
ATOM   2085 C CZ    . TYR A 1 277 ? 94.633  92.080  114.138 1.00 156.78 ? 277 TYR A CZ    1 
ATOM   2086 O OH    . TYR A 1 277 ? 93.720  93.102  114.025 1.00 156.78 ? 277 TYR A OH    1 
ATOM   2087 N N     . GLU A 1 278 ? 99.812  89.528  112.526 1.00 118.73 ? 278 GLU A N     1 
ATOM   2088 C CA    . GLU A 1 278 ? 100.206 90.054  111.217 1.00 118.73 ? 278 GLU A CA    1 
ATOM   2089 C C     . GLU A 1 278 ? 101.053 91.301  111.396 1.00 118.73 ? 278 GLU A C     1 
ATOM   2090 O O     . GLU A 1 278 ? 102.035 91.287  112.152 1.00 118.73 ? 278 GLU A O     1 
ATOM   2091 C CB    . GLU A 1 278 ? 98.971  90.288  110.371 1.00 159.47 ? 278 GLU A CB    1 
ATOM   2092 C CG    . GLU A 1 278 ? 98.173  89.029  110.100 1.00 159.47 ? 278 GLU A CG    1 
ATOM   2093 C CD    . GLU A 1 278 ? 96.994  89.248  109.183 1.00 159.47 ? 278 GLU A CD    1 
ATOM   2094 O OE1   . GLU A 1 278 ? 96.676  90.398  108.886 1.00 159.47 ? 278 GLU A OE1   1 
ATOM   2095 O OE2   . GLU A 1 278 ? 96.386  88.263  108.760 1.00 159.47 ? 278 GLU A OE2   1 
ATOM   2096 N N     . LYS A 1 279 ? 100.721 92.373  110.706 1.00 111.45 ? 279 LYS A N     1 
ATOM   2097 C CA    . LYS A 1 279 ? 101.417 93.631  110.815 1.00 111.45 ? 279 LYS A CA    1 
ATOM   2098 C C     . LYS A 1 279 ? 100.441 94.725  110.433 1.00 111.45 ? 279 LYS A C     1 
ATOM   2099 O O     . LYS A 1 279 ? 99.690  94.583  109.471 1.00 111.45 ? 279 LYS A O     1 
ATOM   2100 C CB    . LYS A 1 279 ? 102.658 93.647  109.919 1.00 167.03 ? 279 LYS A CB    1 
ATOM   2101 C CG    . LYS A 1 279 ? 103.527 94.902  110.048 1.00 167.03 ? 279 LYS A CG    1 
ATOM   2102 C CD    . LYS A 1 279 ? 104.841 94.750  109.281 1.00 167.03 ? 279 LYS A CD    1 
ATOM   2103 C CE    . LYS A 1 279 ? 105.737 95.983  109.423 1.00 167.03 ? 279 LYS A CE    1 
ATOM   2104 N NZ    . LYS A 1 279 ? 107.018 95.828  108.668 1.00 167.03 ? 279 LYS A NZ    1 
ATOM   2105 N N     . MET A 1 280 ? 100.448 95.797  111.189 1.00 102.86 ? 280 MET A N     1 
ATOM   2106 C CA    . MET A 1 280 ? 99.639  96.940  110.849 1.00 102.86 ? 280 MET A CA    1 
ATOM   2107 C C     . MET A 1 280 ? 100.388 97.822  109.869 1.00 102.86 ? 280 MET A C     1 
ATOM   2108 O O     . MET A 1 280 ? 101.611 97.935  109.929 1.00 102.86 ? 280 MET A O     1 
ATOM   2109 C CB    . MET A 1 280 ? 99.307  97.697  112.109 1.00 147.72 ? 280 MET A CB    1 
ATOM   2110 C CG    . MET A 1 280 ? 98.458  96.902  113.022 1.00 147.72 ? 280 MET A CG    1 
ATOM   2111 S SD    . MET A 1 280 ? 98.177  97.735  114.572 1.00 147.72 ? 280 MET A SD    1 
ATOM   2112 C CE    . MET A 1 280 ? 97.086  99.064  114.104 1.00 147.72 ? 280 MET A CE    1 
ATOM   2113 N N     . THR A 1 281 ? 99.661  98.451  108.974 1.00 96.52  ? 281 THR A N     1 
ATOM   2114 C CA    . THR A 1 281 ? 100.312 99.368  108.071 1.00 96.52  ? 281 THR A CA    1 
ATOM   2115 C C     . THR A 1 281 ? 100.494 100.707 108.753 1.00 96.52  ? 281 THR A C     1 
ATOM   2116 O O     . THR A 1 281 ? 99.854  101.000 109.752 1.00 96.52  ? 281 THR A O     1 
ATOM   2117 C CB    . THR A 1 281 ? 99.485  99.559  106.810 1.00 135.11 ? 281 THR A CB    1 
ATOM   2118 O OG1   . THR A 1 281 ? 98.255  100.229 107.129 1.00 135.11 ? 281 THR A OG1   1 
ATOM   2119 C CG2   . THR A 1 281 ? 99.168  98.223  106.198 1.00 135.11 ? 281 THR A CG2   1 
ATOM   2120 N N     . ALA A 1 282 ? 101.335 101.559 108.187 1.00 91.35  ? 282 ALA A N     1 
ATOM   2121 C CA    . ALA A 1 282 ? 101.498 102.870 108.778 1.00 91.35  ? 282 ALA A CA    1 
ATOM   2122 C C     . ALA A 1 282 ? 100.198 103.618 108.769 1.00 91.35  ? 282 ALA A C     1 
ATOM   2123 O O     . ALA A 1 282 ? 99.910  104.357 109.696 1.00 91.35  ? 282 ALA A O     1 
ATOM   2124 C CB    . ALA A 1 282 ? 102.551 103.674 108.029 1.00 124.57 ? 282 ALA A CB    1 
ATOM   2125 N N     . LYS A 1 283 ? 99.387  103.427 107.744 1.00 93.97  ? 283 LYS A N     1 
ATOM   2126 C CA    . LYS A 1 283 ? 98.158  104.196 107.661 1.00 93.97  ? 283 LYS A CA    1 
ATOM   2127 C C     . LYS A 1 283 ? 97.153  103.819 108.733 1.00 93.97  ? 283 LYS A C     1 
ATOM   2128 O O     . LYS A 1 283 ? 96.568  104.705 109.368 1.00 93.97  ? 283 LYS A O     1 
ATOM   2129 C CB    . LYS A 1 283 ? 97.501  104.038 106.306 1.00 140.83 ? 283 LYS A CB    1 
ATOM   2130 C CG    . LYS A 1 283 ? 98.176  104.778 105.228 1.00 140.83 ? 283 LYS A CG    1 
ATOM   2131 C CD    . LYS A 1 283 ? 97.456  104.576 103.933 1.00 140.83 ? 283 LYS A CD    1 
ATOM   2132 C CE    . LYS A 1 283 ? 98.081  105.418 102.829 1.00 140.83 ? 283 LYS A CE    1 
ATOM   2133 N NZ    . LYS A 1 283 ? 97.398  105.236 101.516 1.00 140.83 ? 283 LYS A NZ    1 
ATOM   2134 N N     . GLU A 1 284 ? 96.912  102.526 108.950 1.00 95.57  ? 284 GLU A N     1 
ATOM   2135 C CA    . GLU A 1 284 ? 95.894  102.181 109.930 1.00 95.57  ? 284 GLU A CA    1 
ATOM   2136 C C     . GLU A 1 284 ? 96.392  102.451 111.312 1.00 95.57  ? 284 GLU A C     1 
ATOM   2137 O O     . GLU A 1 284 ? 95.611  102.785 112.201 1.00 95.57  ? 284 GLU A O     1 
ATOM   2138 C CB    . GLU A 1 284 ? 95.464  100.739 109.803 1.00 128.36 ? 284 GLU A CB    1 
ATOM   2139 C CG    . GLU A 1 284 ? 96.503  99.761  110.280 1.00 128.36 ? 284 GLU A CG    1 
ATOM   2140 C CD    . GLU A 1 284 ? 96.175  98.340  109.964 1.00 128.36 ? 284 GLU A CD    1 
ATOM   2141 O OE1   . GLU A 1 284 ? 95.165  97.831  110.454 1.00 128.36 ? 284 GLU A OE1   1 
ATOM   2142 O OE2   . GLU A 1 284 ? 96.947  97.728  109.221 1.00 128.36 ? 284 GLU A OE2   1 
ATOM   2143 N N     . LEU A 1 285 ? 97.684  102.347 111.507 1.00 90.44  ? 285 LEU A N     1 
ATOM   2144 C CA    . LEU A 1 285 ? 98.237  102.556 112.816 1.00 90.44  ? 285 LEU A CA    1 
ATOM   2145 C C     . LEU A 1 285 ? 98.287  104.029 113.147 1.00 90.44  ? 285 LEU A C     1 
ATOM   2146 O O     . LEU A 1 285 ? 97.933  104.418 114.263 1.00 90.44  ? 285 LEU A O     1 
ATOM   2147 C CB    . LEU A 1 285 ? 99.575  101.878 112.889 1.00 133.82 ? 285 LEU A CB    1 
ATOM   2148 C CG    . LEU A 1 285 ? 100.337 101.936 114.167 1.00 133.82 ? 285 LEU A CG    1 
ATOM   2149 C CD1   . LEU A 1 285 ? 99.545  101.449 115.294 1.00 133.82 ? 285 LEU A CD1   1 
ATOM   2150 C CD2   . LEU A 1 285 ? 101.539 101.038 114.000 1.00 133.82 ? 285 LEU A CD2   1 
ATOM   2151 N N     . SER A 1 286 ? 98.640  104.878 112.191 1.00 89.60  ? 286 SER A N     1 
ATOM   2152 C CA    . SER A 1 286 ? 98.605  106.299 112.470 1.00 89.60  ? 286 SER A CA    1 
ATOM   2153 C C     . SER A 1 286 ? 97.193  106.740 112.709 1.00 89.60  ? 286 SER A C     1 
ATOM   2154 O O     . SER A 1 286 ? 96.942  107.574 113.580 1.00 89.60  ? 286 SER A O     1 
ATOM   2155 C CB    . SER A 1 286 ? 99.194  107.092 111.342 1.00 120.68 ? 286 SER A CB    1 
ATOM   2156 O OG    . SER A 1 286 ? 100.571 106.862 111.222 1.00 120.68 ? 286 SER A OG    1 
ATOM   2157 N N     . ALA A 1 287 ? 96.258  106.201 111.951 1.00 90.66  ? 287 ALA A N     1 
ATOM   2158 C CA    . ALA A 1 287 ? 94.875  106.568 112.156 1.00 90.66  ? 287 ALA A CA    1 
ATOM   2159 C C     . ALA A 1 287 ? 94.402  106.217 113.548 1.00 90.66  ? 287 ALA A C     1 
ATOM   2160 O O     . ALA A 1 287 ? 93.698  107.001 114.177 1.00 90.66  ? 287 ALA A O     1 
ATOM   2161 C CB    . ALA A 1 287 ? 94.004  105.879 111.125 1.00 123.63 ? 287 ALA A CB    1 
ATOM   2162 N N     . GLN A 1 288 ? 94.769  105.054 114.059 1.00 86.96  ? 288 GLN A N     1 
ATOM   2163 C CA    . GLN A 1 288 ? 94.359  104.748 115.418 1.00 86.96  ? 288 GLN A CA    1 
ATOM   2164 C C     . GLN A 1 288 ? 94.965  105.710 116.394 1.00 86.96  ? 288 GLN A C     1 
ATOM   2165 O O     . GLN A 1 288 ? 94.285  106.216 117.281 1.00 86.96  ? 288 GLN A O     1 
ATOM   2166 C CB    . GLN A 1 288 ? 94.776  103.351 115.813 1.00 121.48 ? 288 GLN A CB    1 
ATOM   2167 C CG    . GLN A 1 288 ? 94.039  102.277 115.188 1.00 121.48 ? 288 GLN A CG    1 
ATOM   2168 C CD    . GLN A 1 288 ? 94.503  100.980 115.700 1.00 121.48 ? 288 GLN A CD    1 
ATOM   2169 O OE1   . GLN A 1 288 ? 95.445  100.924 116.457 1.00 121.48 ? 288 GLN A OE1   1 
ATOM   2170 N NE2   . GLN A 1 288 ? 93.840  99.911  115.304 1.00 121.48 ? 288 GLN A NE2   1 
ATOM   2171 N N     . VAL A 1 289 ? 96.238  106.001 116.242 1.00 84.63  ? 289 VAL A N     1 
ATOM   2172 C CA    . VAL A 1 289 ? 96.891  106.795 117.253 1.00 84.63  ? 289 VAL A CA    1 
ATOM   2173 C C     . VAL A 1 289 ? 96.280  108.171 117.346 1.00 84.63  ? 289 VAL A C     1 
ATOM   2174 O O     . VAL A 1 289 ? 96.083  108.695 118.448 1.00 84.63  ? 289 VAL A O     1 
ATOM   2175 C CB    . VAL A 1 289 ? 98.379  106.841 116.991 1.00 123.06 ? 289 VAL A CB    1 
ATOM   2176 C CG1   . VAL A 1 289 ? 99.042  107.856 117.860 1.00 123.06 ? 289 VAL A CG1   1 
ATOM   2177 C CG2   . VAL A 1 289 ? 98.936  105.488 117.300 1.00 123.06 ? 289 VAL A CG2   1 
ATOM   2178 N N     . PHE A 1 290 ? 95.940  108.759 116.221 1.00 84.96  ? 290 PHE A N     1 
ATOM   2179 C CA    . PHE A 1 290 ? 95.356  110.087 116.180 1.00 84.96  ? 290 PHE A CA    1 
ATOM   2180 C C     . PHE A 1 290 ? 93.856  110.078 116.224 1.00 84.96  ? 290 PHE A C     1 
ATOM   2181 O O     . PHE A 1 290 ? 93.244  111.122 116.026 1.00 84.96  ? 290 PHE A O     1 
ATOM   2182 C CB    . PHE A 1 290 ? 95.793  110.832 114.937 1.00 118.51 ? 290 PHE A CB    1 
ATOM   2183 C CG    . PHE A 1 290 ? 97.127  111.402 115.040 1.00 118.51 ? 290 PHE A CG    1 
ATOM   2184 C CD1   . PHE A 1 290 ? 98.220  110.672 114.742 1.00 118.51 ? 290 PHE A CD1   1 
ATOM   2185 C CD2   . PHE A 1 290 ? 97.285  112.675 115.443 1.00 118.51 ? 290 PHE A CD2   1 
ATOM   2186 C CE1   . PHE A 1 290 ? 99.445  111.216 114.852 1.00 118.51 ? 290 PHE A CE1   1 
ATOM   2187 C CE2   . PHE A 1 290 ? 98.515  113.231 115.549 1.00 118.51 ? 290 PHE A CE2   1 
ATOM   2188 C CZ    . PHE A 1 290 ? 99.584  112.507 115.254 1.00 118.51 ? 290 PHE A CZ    1 
ATOM   2189 N N     . GLY A 1 291 ? 93.252  108.952 116.437 1.00 87.64  ? 291 GLY A N     1 
ATOM   2190 C CA    . GLY A 1 291 ? 91.816  108.927 116.551 1.00 87.64  ? 291 GLY A CA    1 
ATOM   2191 C C     . GLY A 1 291 ? 91.473  109.267 117.962 1.00 87.64  ? 291 GLY A C     1 
ATOM   2192 O O     . GLY A 1 291 ? 92.349  109.361 118.799 1.00 87.64  ? 291 GLY A O     1 
ATOM   2193 N N     . ASP A 1 292 ? 90.202  109.438 118.251 1.00 89.60  ? 292 ASP A N     1 
ATOM   2194 C CA    . ASP A 1 292 ? 89.870  109.770 119.615 1.00 89.60  ? 292 ASP A CA    1 
ATOM   2195 C C     . ASP A 1 292 ? 89.865  108.535 120.492 1.00 89.60  ? 292 ASP A C     1 
ATOM   2196 O O     . ASP A 1 292 ? 90.122  108.617 121.693 1.00 89.60  ? 292 ASP A O     1 
ATOM   2197 C CB    . ASP A 1 292 ? 88.517  110.447 119.675 1.00 115.20 ? 292 ASP A CB    1 
ATOM   2198 C CG    . ASP A 1 292 ? 88.469  111.797 118.965 1.00 115.20 ? 292 ASP A CG    1 
ATOM   2199 O OD1   . ASP A 1 292 ? 89.504  112.435 118.703 1.00 115.20 ? 292 ASP A OD1   1 
ATOM   2200 O OD2   . ASP A 1 292 ? 87.348  112.223 118.662 1.00 115.20 ? 292 ASP A OD2   1 
ATOM   2201 N N     . GLU A 1 293 ? 89.639  107.376 119.891 1.00 89.23  ? 293 GLU A N     1 
ATOM   2202 C CA    . GLU A 1 293 ? 89.444  106.132 120.611 1.00 89.23  ? 293 GLU A CA    1 
ATOM   2203 C C     . GLU A 1 293 ? 90.661  105.605 121.354 1.00 89.23  ? 293 GLU A C     1 
ATOM   2204 O O     . GLU A 1 293 ? 90.481  104.817 122.284 1.00 89.23  ? 293 GLU A O     1 
ATOM   2205 C CB    . GLU A 1 293 ? 88.955  105.088 119.636 1.00 119.85 ? 293 GLU A CB    1 
ATOM   2206 C CG    . GLU A 1 293 ? 89.858  104.884 118.420 1.00 119.85 ? 293 GLU A CG    1 
ATOM   2207 C CD    . GLU A 1 293 ? 89.518  105.793 117.257 1.00 119.85 ? 293 GLU A CD    1 
ATOM   2208 O OE1   . GLU A 1 293 ? 88.878  106.823 117.475 1.00 119.85 ? 293 GLU A OE1   1 
ATOM   2209 O OE2   . GLU A 1 293 ? 89.886  105.472 116.129 1.00 119.85 ? 293 GLU A OE2   1 
ATOM   2210 N N     . TYR A 1 294 ? 91.881  105.985 121.006 1.00 89.10  ? 294 TYR A N     1 
ATOM   2211 C CA    . TYR A 1 294 ? 93.032  105.522 121.767 1.00 89.10  ? 294 TYR A CA    1 
ATOM   2212 C C     . TYR A 1 294 ? 93.656  106.583 122.633 1.00 89.10  ? 294 TYR A C     1 
ATOM   2213 O O     . TYR A 1 294 ? 94.724  106.364 123.191 1.00 89.10  ? 294 TYR A O     1 
ATOM   2214 C CB    . TYR A 1 294 ? 94.073  104.962 120.855 1.00 123.32 ? 294 TYR A CB    1 
ATOM   2215 C CG    . TYR A 1 294 ? 93.730  103.637 120.366 1.00 123.32 ? 294 TYR A CG    1 
ATOM   2216 C CD1   . TYR A 1 294 ? 94.038  102.540 121.112 1.00 123.32 ? 294 TYR A CD1   1 
ATOM   2217 C CD2   . TYR A 1 294 ? 93.133  103.462 119.159 1.00 123.32 ? 294 TYR A CD2   1 
ATOM   2218 C CE1   . TYR A 1 294 ? 93.742  101.293 120.681 1.00 123.32 ? 294 TYR A CE1   1 
ATOM   2219 C CE2   . TYR A 1 294 ? 92.824  102.213 118.713 1.00 123.32 ? 294 TYR A CE2   1 
ATOM   2220 C CZ    . TYR A 1 294 ? 93.132  101.128 119.481 1.00 123.32 ? 294 TYR A CZ    1 
ATOM   2221 O OH    . TYR A 1 294 ? 92.845  99.861  119.039 1.00 123.32 ? 294 TYR A OH    1 
ATOM   2222 N N     . ILE A 1 295 ? 93.024  107.718 122.794 1.00 89.85  ? 295 ILE A N     1 
ATOM   2223 C CA    . ILE A 1 295 ? 93.626  108.751 123.605 1.00 89.85  ? 295 ILE A CA    1 
ATOM   2224 C C     . ILE A 1 295 ? 93.500  108.325 125.042 1.00 89.85  ? 295 ILE A C     1 
ATOM   2225 O O     . ILE A 1 295 ? 92.428  107.933 125.476 1.00 89.85  ? 295 ILE A O     1 
ATOM   2226 C CB    . ILE A 1 295 ? 92.946  110.088 123.359 1.00 132.94 ? 295 ILE A CB    1 
ATOM   2227 C CG1   . ILE A 1 295 ? 92.949  110.400 121.867 1.00 132.94 ? 295 ILE A CG1   1 
ATOM   2228 C CG2   . ILE A 1 295 ? 93.603  111.204 124.143 1.00 132.94 ? 295 ILE A CG2   1 
ATOM   2229 C CD1   . ILE A 1 295 ? 94.286  110.548 121.199 1.00 132.94 ? 295 ILE A CD1   1 
ATOM   2230 N N     . CYS A 1 296 ? 94.572  108.404 125.795 1.00 97.89  ? 296 CYS A N     1 
ATOM   2231 C CA    . CYS A 1 296 ? 94.562  107.928 127.165 1.00 97.89  ? 296 CYS A CA    1 
ATOM   2232 C C     . CYS A 1 296 ? 94.188  108.998 128.162 1.00 97.89  ? 296 CYS A C     1 
ATOM   2233 O O     . CYS A 1 296 ? 94.511  108.884 129.353 1.00 97.89  ? 296 CYS A O     1 
ATOM   2234 C CB    . CYS A 1 296 ? 95.909  107.328 127.500 1.00 131.85 ? 296 CYS A CB    1 
ATOM   2235 S SG    . CYS A 1 296 ? 96.228  105.845 126.542 1.00 131.85 ? 296 CYS A SG    1 
ATOM   2236 N N     . ALA A 1 297 ? 93.479  110.001 127.696 1.00 96.39  ? 297 ALA A N     1 
ATOM   2237 C CA    . ALA A 1 297 ? 92.929  111.089 128.471 1.00 96.39  ? 297 ALA A CA    1 
ATOM   2238 C C     . ALA A 1 297 ? 91.526  111.330 127.952 1.00 96.39  ? 297 ALA A C     1 
ATOM   2239 O O     . ALA A 1 297 ? 91.272  111.202 126.757 1.00 96.39  ? 297 ALA A O     1 
ATOM   2240 C CB    . ALA A 1 297 ? 93.759  112.333 128.313 1.00 131.44 ? 297 ALA A CB    1 
ATOM   2241 N N     . ALA A 1 298 ? 90.618  111.703 128.826 1.00 99.04  ? 298 ALA A N     1 
ATOM   2242 C CA    . ALA A 1 298 ? 89.219  111.833 128.446 1.00 99.04  ? 298 ALA A CA    1 
ATOM   2243 C C     . ALA A 1 298 ? 88.994  113.139 127.704 1.00 99.04  ? 298 ALA A C     1 
ATOM   2244 O O     . ALA A 1 298 ? 88.444  114.117 128.215 1.00 99.04  ? 298 ALA A O     1 
ATOM   2245 C CB    . ALA A 1 298 ? 88.341  111.746 129.673 1.00 135.05 ? 298 ALA A CB    1 
ATOM   2246 N N     . CYS A 1 299 ? 89.442  113.125 126.478 1.00 87.00  ? 299 CYS A N     1 
ATOM   2247 C CA    . CYS A 1 299 ? 89.454  114.265 125.608 1.00 87.00  ? 299 CYS A CA    1 
ATOM   2248 C C     . CYS A 1 299 ? 88.921  113.813 124.281 1.00 87.00  ? 299 CYS A C     1 
ATOM   2249 O O     . CYS A 1 299 ? 88.735  112.623 124.049 1.00 87.00  ? 299 CYS A O     1 
ATOM   2250 C CB    . CYS A 1 299 ? 90.857  114.771 125.461 1.00 117.18 ? 299 CYS A CB    1 
ATOM   2251 S SG    . CYS A 1 299 ? 91.599  115.105 127.047 1.00 117.18 ? 299 CYS A SG    1 
ATOM   2252 N N     . LYS A 1 300 ? 88.685  114.735 123.392 1.00 81.96  ? 300 LYS A N     1 
ATOM   2253 C CA    . LYS A 1 300 ? 88.269  114.384 122.057 1.00 81.96  ? 300 LYS A CA    1 
ATOM   2254 C C     . LYS A 1 300 ? 89.081  115.209 121.070 1.00 81.96  ? 300 LYS A C     1 
ATOM   2255 O O     . LYS A 1 300 ? 88.536  116.083 120.396 1.00 81.96  ? 300 LYS A O     1 
ATOM   2256 C CB    . LYS A 1 300 ? 86.767  114.593 121.953 1.00 122.83 ? 300 LYS A CB    1 
ATOM   2257 C CG    . LYS A 1 300 ? 86.175  114.095 120.733 1.00 122.83 ? 300 LYS A CG    1 
ATOM   2258 C CD    . LYS A 1 300 ? 84.693  114.229 120.734 1.00 122.83 ? 300 LYS A CD    1 
ATOM   2259 C CE    . LYS A 1 300 ? 84.131  113.851 119.357 1.00 122.83 ? 300 LYS A CE    1 
ATOM   2260 N NZ    . LYS A 1 300 ? 84.460  112.441 118.958 1.00 122.83 ? 300 LYS A NZ    1 
ATOM   2261 N N     . PRO A 1 301 ? 90.382  114.902 120.935 1.00 83.14  ? 301 PRO A N     1 
ATOM   2262 C CA    . PRO A 1 301 ? 91.378  115.766 120.294 1.00 83.14  ? 301 PRO A CA    1 
ATOM   2263 C C     . PRO A 1 301 ? 91.131  116.086 118.853 1.00 83.14  ? 301 PRO A C     1 
ATOM   2264 O O     . PRO A 1 301 ? 91.620  117.114 118.376 1.00 83.14  ? 301 PRO A O     1 
ATOM   2265 C CB    . PRO A 1 301 ? 92.644  114.945 120.427 1.00 259.32 ? 301 PRO A CB    1 
ATOM   2266 C CG    . PRO A 1 301 ? 92.389  114.092 121.520 1.00 259.32 ? 301 PRO A CG    1 
ATOM   2267 C CD    . PRO A 1 301 ? 90.988  113.697 121.420 1.00 259.32 ? 301 PRO A CD    1 
ATOM   2268 N N     . THR A 1 302 ? 90.370  115.294 118.132 1.00 79.75  ? 302 THR A N     1 
ATOM   2269 C CA    . THR A 1 302 ? 90.156  115.657 116.757 1.00 79.75  ? 302 THR A CA    1 
ATOM   2270 C C     . THR A 1 302 ? 89.413  116.953 116.609 1.00 79.75  ? 302 THR A C     1 
ATOM   2271 O O     . THR A 1 302 ? 89.486  117.564 115.548 1.00 79.75  ? 302 THR A O     1 
ATOM   2272 C CB    . THR A 1 302 ? 89.422  114.565 116.030 1.00 111.64 ? 302 THR A CB    1 
ATOM   2273 O OG1   . THR A 1 302 ? 89.613  114.739 114.626 1.00 111.64 ? 302 THR A OG1   1 
ATOM   2274 C CG2   . THR A 1 302 ? 87.952  114.602 116.340 1.00 111.64 ? 302 THR A CG2   1 
ATOM   2275 N N     . THR A 1 303 ? 88.701  117.399 117.625 1.00 80.41  ? 303 THR A N     1 
ATOM   2276 C CA    . THR A 1 303 ? 87.933  118.625 117.533 1.00 80.41  ? 303 THR A CA    1 
ATOM   2277 C C     . THR A 1 303 ? 88.710  119.845 117.934 1.00 80.41  ? 303 THR A C     1 
ATOM   2278 O O     . THR A 1 303 ? 88.175  120.947 117.870 1.00 80.41  ? 303 THR A O     1 
ATOM   2279 C CB    . THR A 1 303 ? 86.705  118.585 118.413 1.00 112.56 ? 303 THR A CB    1 
ATOM   2280 O OG1   . THR A 1 303 ? 87.102  118.589 119.787 1.00 112.56 ? 303 THR A OG1   1 
ATOM   2281 C CG2   . THR A 1 303 ? 85.917  117.369 118.143 1.00 112.56 ? 303 THR A CG2   1 
ATOM   2282 N N     . GLY A 1 304 ? 89.938  119.692 118.343 1.00 81.18  ? 304 GLY A N     1 
ATOM   2283 C CA    . GLY A 1 304 ? 90.680  120.831 118.801 1.00 81.18  ? 304 GLY A CA    1 
ATOM   2284 C C     . GLY A 1 304 ? 91.738  121.243 117.834 1.00 81.18  ? 304 GLY A C     1 
ATOM   2285 O O     . GLY A 1 304 ? 91.582  121.091 116.625 1.00 81.18  ? 304 GLY A O     1 
ATOM   2286 N N     . ARG A 1 305 ? 92.794  121.826 118.354 1.00 87.09  ? 305 ARG A N     1 
ATOM   2287 C CA    . ARG A 1 305 ? 93.899  122.282 117.559 1.00 87.09  ? 305 ARG A CA    1 
ATOM   2288 C C     . ARG A 1 305 ? 95.187  121.952 118.278 1.00 87.09  ? 305 ARG A C     1 
ATOM   2289 O O     . ARG A 1 305 ? 95.262  122.055 119.492 1.00 87.09  ? 305 ARG A O     1 
ATOM   2290 C CB    . ARG A 1 305 ? 93.780  123.769 117.315 1.00 127.86 ? 305 ARG A CB    1 
ATOM   2291 C CG    . ARG A 1 305 ? 92.576  124.136 116.490 1.00 127.86 ? 305 ARG A CG    1 
ATOM   2292 C CD    . ARG A 1 305 ? 92.350  125.586 116.390 1.00 127.86 ? 305 ARG A CD    1 
ATOM   2293 N NE    . ARG A 1 305 ? 93.438  126.261 115.730 1.00 127.86 ? 305 ARG A NE    1 
ATOM   2294 C CZ    . ARG A 1 305 ? 93.552  126.385 114.423 1.00 127.86 ? 305 ARG A CZ    1 
ATOM   2295 N NH1   . ARG A 1 305 ? 92.683  125.837 113.598 1.00 127.86 ? 305 ARG A NH1   1 
ATOM   2296 N NH2   . ARG A 1 305 ? 94.565  127.074 113.930 1.00 127.86 ? 305 ARG A NH2   1 
ATOM   2297 N N     . TYR A 1 306 ? 96.198  121.539 117.540 1.00 84.87  ? 306 TYR A N     1 
ATOM   2298 C CA    . TYR A 1 306 ? 97.467  121.162 118.143 1.00 84.87  ? 306 TYR A CA    1 
ATOM   2299 C C     . TYR A 1 306 ? 98.504  122.268 118.107 1.00 84.87  ? 306 TYR A C     1 
ATOM   2300 O O     . TYR A 1 306 ? 98.716  122.916 117.081 1.00 84.87  ? 306 TYR A O     1 
ATOM   2301 C CB    . TYR A 1 306 ? 98.066  119.979 117.416 1.00 117.47 ? 306 TYR A CB    1 
ATOM   2302 C CG    . TYR A 1 306 ? 97.457  118.640 117.628 1.00 117.47 ? 306 TYR A CG    1 
ATOM   2303 C CD1   . TYR A 1 306 ? 96.451  118.195 116.836 1.00 117.47 ? 306 TYR A CD1   1 
ATOM   2304 C CD2   . TYR A 1 306 ? 97.933  117.812 118.570 1.00 117.47 ? 306 TYR A CD2   1 
ATOM   2305 C CE1   . TYR A 1 306 ? 95.933  116.986 117.000 1.00 117.47 ? 306 TYR A CE1   1 
ATOM   2306 C CE2   . TYR A 1 306 ? 97.423  116.601 118.731 1.00 117.47 ? 306 TYR A CE2   1 
ATOM   2307 C CZ    . TYR A 1 306 ? 96.411  116.190 117.949 1.00 117.47 ? 306 TYR A CZ    1 
ATOM   2308 O OH    . TYR A 1 306 ? 95.887  114.949 118.120 1.00 117.47 ? 306 TYR A OH    1 
ATOM   2309 N N     . LEU A 1 307 ? 99.184  122.459 119.210 1.00 83.12  ? 307 LEU A N     1 
ATOM   2310 C CA    . LEU A 1 307 ? 100.289 123.388 119.219 1.00 83.12  ? 307 LEU A CA    1 
ATOM   2311 C C     . LEU A 1 307 ? 101.517 122.663 118.770 1.00 83.12  ? 307 LEU A C     1 
ATOM   2312 O O     . LEU A 1 307 ? 102.376 123.226 118.097 1.00 83.12  ? 307 LEU A O     1 
ATOM   2313 C CB    . LEU A 1 307 ? 100.537 123.964 120.603 1.00 122.99 ? 307 LEU A CB    1 
ATOM   2314 C CG    . LEU A 1 307 ? 99.522  124.892 121.222 1.00 122.99 ? 307 LEU A CG    1 
ATOM   2315 C CD1   . LEU A 1 307 ? 99.830  125.089 122.680 1.00 122.99 ? 307 LEU A CD1   1 
ATOM   2316 C CD2   . LEU A 1 307 ? 99.559  126.245 120.521 1.00 122.99 ? 307 LEU A CD2   1 
ATOM   2317 N N     . ALA A 1 308 ? 101.626 121.416 119.158 1.00 78.72  ? 308 ALA A N     1 
ATOM   2318 C CA    . ALA A 1 308 ? 102.776 120.643 118.768 1.00 78.72  ? 308 ALA A CA    1 
ATOM   2319 C C     . ALA A 1 308 ? 102.462 119.178 118.917 1.00 78.72  ? 308 ALA A C     1 
ATOM   2320 O O     . ALA A 1 308 ? 101.582 118.795 119.683 1.00 78.72  ? 308 ALA A O     1 
ATOM   2321 C CB    . ALA A 1 308 ? 103.978 120.998 119.602 1.00 107.34 ? 308 ALA A CB    1 
ATOM   2322 N N     . ALA A 1 309 ? 103.196 118.358 118.200 1.00 74.45  ? 309 ALA A N     1 
ATOM   2323 C CA    . ALA A 1 309 ? 103.025 116.934 118.312 1.00 74.45  ? 309 ALA A CA    1 
ATOM   2324 C C     . ALA A 1 309 ? 104.306 116.223 117.964 1.00 74.45  ? 309 ALA A C     1 
ATOM   2325 O O     . ALA A 1 309 ? 105.124 116.733 117.202 1.00 74.45  ? 309 ALA A O     1 
ATOM   2326 C CB    . ALA A 1 309 ? 101.918 116.444 117.419 1.00 101.52 ? 309 ALA A CB    1 
ATOM   2327 N N     . SER A 1 310 ? 104.458 115.026 118.486 1.00 74.62  ? 310 SER A N     1 
ATOM   2328 C CA    . SER A 1 310 ? 105.624 114.207 118.220 1.00 74.62  ? 310 SER A CA    1 
ATOM   2329 C C     . SER A 1 310 ? 105.217 112.762 118.038 1.00 74.62  ? 310 SER A C     1 
ATOM   2330 O O     . SER A 1 310 ? 104.565 112.193 118.908 1.00 74.62  ? 310 SER A O     1 
ATOM   2331 C CB    . SER A 1 310 ? 106.621 114.335 119.346 1.00 100.51 ? 310 SER A CB    1 
ATOM   2332 O OG    . SER A 1 310 ? 107.698 113.474 119.128 1.00 100.51 ? 310 SER A OG    1 
ATOM   2333 N N     . VAL A 1 311 ? 105.555 112.166 116.909 1.00 70.58  ? 311 VAL A N     1 
ATOM   2334 C CA    . VAL A 1 311 ? 105.132 110.823 116.602 1.00 70.58  ? 311 VAL A CA    1 
ATOM   2335 C C     . VAL A 1 311 ? 106.303 109.917 116.356 1.00 70.58  ? 311 VAL A C     1 
ATOM   2336 O O     . VAL A 1 311 ? 107.030 110.097 115.380 1.00 70.58  ? 311 VAL A O     1 
ATOM   2337 C CB    . VAL A 1 311 ? 104.232 110.817 115.385 1.00 102.63 ? 311 VAL A CB    1 
ATOM   2338 C CG1   . VAL A 1 311 ? 103.813 109.468 115.039 1.00 102.63 ? 311 VAL A CG1   1 
ATOM   2339 C CG2   . VAL A 1 311 ? 103.088 111.636 115.665 1.00 102.63 ? 311 VAL A CG2   1 
ATOM   2340 N N     . LEU A 1 312 ? 106.407 108.867 117.138 1.00 73.64  ? 312 LEU A N     1 
ATOM   2341 C CA    . LEU A 1 312 ? 107.472 107.896 117.010 1.00 73.64  ? 312 LEU A CA    1 
ATOM   2342 C C     . LEU A 1 312 ? 106.985 106.583 116.455 1.00 73.64  ? 312 LEU A C     1 
ATOM   2343 O O     . LEU A 1 312 ? 106.037 105.983 116.976 1.00 73.64  ? 312 LEU A O     1 
ATOM   2344 C CB    . LEU A 1 312 ? 108.110 107.614 118.347 1.00 108.96 ? 312 LEU A CB    1 
ATOM   2345 C CG    . LEU A 1 312 ? 109.116 106.480 118.383 1.00 108.96 ? 312 LEU A CG    1 
ATOM   2346 C CD1   . LEU A 1 312 ? 110.295 106.763 117.552 1.00 108.96 ? 312 LEU A CD1   1 
ATOM   2347 C CD2   . LEU A 1 312 ? 109.552 106.241 119.791 1.00 108.96 ? 312 LEU A CD2   1 
ATOM   2348 N N     . PHE A 1 313 ? 107.661 106.107 115.437 1.00 75.75  ? 313 PHE A N     1 
ATOM   2349 C CA    . PHE A 1 313 ? 107.379 104.802 114.876 1.00 75.75  ? 313 PHE A CA    1 
ATOM   2350 C C     . PHE A 1 313 ? 108.465 103.835 115.306 1.00 75.75  ? 313 PHE A C     1 
ATOM   2351 O O     . PHE A 1 313 ? 109.631 104.011 114.957 1.00 75.75  ? 313 PHE A O     1 
ATOM   2352 C CB    . PHE A 1 313 ? 107.324 104.845 113.375 1.00 105.66 ? 313 PHE A CB    1 
ATOM   2353 C CG    . PHE A 1 313 ? 106.156 105.463 112.835 1.00 105.66 ? 313 PHE A CG    1 
ATOM   2354 C CD1   . PHE A 1 313 ? 106.046 106.796 112.777 1.00 105.66 ? 313 PHE A CD1   1 
ATOM   2355 C CD2   . PHE A 1 313 ? 105.222 104.729 112.248 1.00 105.66 ? 313 PHE A CD2   1 
ATOM   2356 C CE1   . PHE A 1 313 ? 104.981 107.357 112.202 1.00 105.66 ? 313 PHE A CE1   1 
ATOM   2357 C CE2   . PHE A 1 313 ? 104.155 105.282 111.681 1.00 105.66 ? 313 PHE A CE2   1 
ATOM   2358 C CZ    . PHE A 1 313 ? 104.031 106.591 111.657 1.00 105.66 ? 313 PHE A CZ    1 
ATOM   2359 N N     . ARG A 1 314 ? 108.101 102.822 116.050 1.00 82.00  ? 314 ARG A N     1 
ATOM   2360 C CA    . ARG A 1 314 ? 109.061 101.855 116.539 1.00 82.00  ? 314 ARG A CA    1 
ATOM   2361 C C     . ARG A 1 314 ? 108.918 100.587 115.743 1.00 82.00  ? 314 ARG A C     1 
ATOM   2362 O O     . ARG A 1 314 ? 107.948 99.853  115.924 1.00 82.00  ? 314 ARG A O     1 
ATOM   2363 C CB    . ARG A 1 314 ? 108.811 101.530 117.989 1.00 120.39 ? 314 ARG A CB    1 
ATOM   2364 C CG    . ARG A 1 314 ? 109.032 102.626 118.935 1.00 120.39 ? 314 ARG A CG    1 
ATOM   2365 C CD    . ARG A 1 314 ? 108.912 102.108 120.303 1.00 120.39 ? 314 ARG A CD    1 
ATOM   2366 N NE    . ARG A 1 314 ? 109.943 101.142 120.491 1.00 120.39 ? 314 ARG A NE    1 
ATOM   2367 C CZ    . ARG A 1 314 ? 110.136 100.390 121.547 1.00 120.39 ? 314 ARG A CZ    1 
ATOM   2368 N NH1   . ARG A 1 314 ? 109.361 100.454 122.607 1.00 120.39 ? 314 ARG A NH1   1 
ATOM   2369 N NH2   . ARG A 1 314 ? 111.138 99.530  121.524 1.00 120.39 ? 314 ARG A NH2   1 
ATOM   2370 N N     . GLY A 1 315 ? 109.866 100.300 114.886 1.00 80.46  ? 315 GLY A N     1 
ATOM   2371 C CA    . GLY A 1 315 ? 109.769 99.116  114.074 1.00 80.46  ? 315 GLY A CA    1 
ATOM   2372 C C     . GLY A 1 315 ? 110.139 99.362  112.633 1.00 80.46  ? 315 GLY A C     1 
ATOM   2373 O O     . GLY A 1 315 ? 110.477 100.463 112.214 1.00 80.46  ? 315 GLY A O     1 
ATOM   2374 N N     . ALA A 1 316 ? 110.019 98.314  111.853 1.00 78.71  ? 316 ALA A N     1 
ATOM   2375 C CA    . ALA A 1 316 ? 110.431 98.339  110.463 1.00 78.71  ? 316 ALA A CA    1 
ATOM   2376 C C     . ALA A 1 316 ? 109.364 98.926  109.556 1.00 78.71  ? 316 ALA A C     1 
ATOM   2377 O O     . ALA A 1 316 ? 108.592 98.212  108.921 1.00 78.71  ? 316 ALA A O     1 
ATOM   2378 C CB    . ALA A 1 316 ? 110.757 96.926  110.015 1.00 107.33 ? 316 ALA A CB    1 
ATOM   2379 N N     . VAL A 1 317 ? 109.355 100.236 109.446 1.00 80.70  ? 317 VAL A N     1 
ATOM   2380 C CA    . VAL A 1 317 ? 108.411 100.920 108.584 1.00 80.70  ? 317 VAL A CA    1 
ATOM   2381 C C     . VAL A 1 317 ? 109.190 101.715 107.557 1.00 80.70  ? 317 VAL A C     1 
ATOM   2382 O O     . VAL A 1 317 ? 110.216 102.312 107.878 1.00 80.70  ? 317 VAL A O     1 
ATOM   2383 C CB    . VAL A 1 317 ? 107.473 101.810 109.399 1.00 117.34 ? 317 VAL A CB    1 
ATOM   2384 C CG1   . VAL A 1 317 ? 108.244 102.891 110.123 1.00 117.34 ? 317 VAL A CG1   1 
ATOM   2385 C CG2   . VAL A 1 317 ? 106.401 102.389 108.520 1.00 117.34 ? 317 VAL A CG2   1 
ATOM   2386 N N     . LYS A 1 318 ? 108.731 101.699 106.315 1.00 82.97  ? 318 LYS A N     1 
ATOM   2387 C CA    . LYS A 1 318 ? 109.384 102.445 105.248 1.00 82.97  ? 318 LYS A CA    1 
ATOM   2388 C C     . LYS A 1 318 ? 109.127 103.939 105.337 1.00 82.97  ? 318 LYS A C     1 
ATOM   2389 O O     . LYS A 1 318 ? 108.017 104.371 105.647 1.00 82.97  ? 318 LYS A O     1 
ATOM   2390 C CB    . LYS A 1 318 ? 108.895 101.967 103.895 1.00 124.34 ? 318 LYS A CB    1 
ATOM   2391 C CG    . LYS A 1 318 ? 109.289 100.609 103.528 1.00 124.34 ? 318 LYS A CG    1 
ATOM   2392 C CD    . LYS A 1 318 ? 108.782 100.291 102.166 1.00 124.34 ? 318 LYS A CD    1 
ATOM   2393 C CE    . LYS A 1 318 ? 109.122 98.891  101.759 1.00 124.34 ? 318 LYS A CE    1 
ATOM   2394 N NZ    . LYS A 1 318 ? 108.565 98.552  100.422 1.00 124.34 ? 318 LYS A NZ    1 
ATOM   2395 N N     . THR A 1 319 ? 110.141 104.731 104.974 1.00 77.77  ? 319 THR A N     1 
ATOM   2396 C CA    . THR A 1 319 ? 110.036 106.185 104.993 1.00 77.77  ? 319 THR A CA    1 
ATOM   2397 C C     . THR A 1 319 ? 108.887 106.679 104.146 1.00 77.77  ? 319 THR A C     1 
ATOM   2398 O O     . THR A 1 319 ? 108.149 107.571 104.567 1.00 77.77  ? 319 THR A O     1 
ATOM   2399 C CB    . THR A 1 319 ? 111.329 106.812 104.504 1.00 108.86 ? 319 THR A CB    1 
ATOM   2400 O OG1   . THR A 1 319 ? 112.397 106.462 105.381 1.00 108.86 ? 319 THR A OG1   1 
ATOM   2401 C CG2   . THR A 1 319 ? 111.210 108.328 104.433 1.00 108.86 ? 319 THR A CG2   1 
ATOM   2402 N N     . SER A 1 320 ? 108.692 106.120 102.977 1.00 76.04  ? 320 SER A N     1 
ATOM   2403 C CA    . SER A 1 320 ? 107.620 106.600 102.147 1.00 76.04  ? 320 SER A CA    1 
ATOM   2404 C C     . SER A 1 320 ? 106.242 106.298 102.708 1.00 76.04  ? 320 SER A C     1 
ATOM   2405 O O     . SER A 1 320 ? 105.310 107.073 102.458 1.00 76.04  ? 320 SER A O     1 
ATOM   2406 C CB    . SER A 1 320 ? 107.716 106.028 100.772 1.00 102.42 ? 320 SER A CB    1 
ATOM   2407 O OG    . SER A 1 320 ? 107.479 104.654 100.807 1.00 102.42 ? 320 SER A OG    1 
ATOM   2408 N N     . ASP A 1 321 ? 106.077 105.242 103.516 1.00 84.56  ? 321 ASP A N     1 
ATOM   2409 C CA    . ASP A 1 321 ? 104.759 104.966 104.089 1.00 84.56  ? 321 ASP A CA    1 
ATOM   2410 C C     . ASP A 1 321 ? 104.516 105.848 105.282 1.00 84.56  ? 321 ASP A C     1 
ATOM   2411 O O     . ASP A 1 321 ? 103.388 106.278 105.524 1.00 84.56  ? 321 ASP A O     1 
ATOM   2412 C CB    . ASP A 1 321 ? 104.617 103.518 104.537 1.00 108.72 ? 321 ASP A CB    1 
ATOM   2413 C CG    . ASP A 1 321 ? 104.639 102.533 103.404 1.00 108.72 ? 321 ASP A CG    1 
ATOM   2414 O OD1   . ASP A 1 321 ? 104.066 102.811 102.351 1.00 108.72 ? 321 ASP A OD1   1 
ATOM   2415 O OD2   . ASP A 1 321 ? 105.213 101.457 103.587 1.00 108.72 ? 321 ASP A OD2   1 
ATOM   2416 N N     . VAL A 1 322 ? 105.572 106.148 106.016 1.00 78.63  ? 322 VAL A N     1 
ATOM   2417 C CA    . VAL A 1 322 ? 105.428 107.053 107.117 1.00 78.63  ? 322 VAL A CA    1 
ATOM   2418 C C     . VAL A 1 322 ? 104.986 108.381 106.600 1.00 78.63  ? 322 VAL A C     1 
ATOM   2419 O O     . VAL A 1 322 ? 104.059 108.980 107.134 1.00 78.63  ? 322 VAL A O     1 
ATOM   2420 C CB    . VAL A 1 322 ? 106.730 107.206 107.900 1.00 114.33 ? 322 VAL A CB    1 
ATOM   2421 C CG1   . VAL A 1 322 ? 106.589 108.275 108.904 1.00 114.33 ? 322 VAL A CG1   1 
ATOM   2422 C CG2   . VAL A 1 322 ? 107.048 105.976 108.574 1.00 114.33 ? 322 VAL A CG2   1 
ATOM   2423 N N     . ASN A 1 323 ? 105.617 108.860 105.550 1.00 77.14  ? 323 ASN A N     1 
ATOM   2424 C CA    . ASN A 1 323 ? 105.276 110.180 105.090 1.00 77.14  ? 323 ASN A CA    1 
ATOM   2425 C C     . ASN A 1 323 ? 103.901 110.236 104.471 1.00 77.14  ? 323 ASN A C     1 
ATOM   2426 O O     . ASN A 1 323 ? 103.189 111.219 104.680 1.00 77.14  ? 323 ASN A O     1 
ATOM   2427 C CB    . ASN A 1 323 ? 106.313 110.663 104.146 1.00 104.50 ? 323 ASN A CB    1 
ATOM   2428 C CG    . ASN A 1 323 ? 107.541 111.008 104.864 1.00 104.50 ? 323 ASN A CG    1 
ATOM   2429 O OD1   . ASN A 1 323 ? 107.517 111.268 106.057 1.00 104.50 ? 323 ASN A OD1   1 
ATOM   2430 N ND2   . ASN A 1 323 ? 108.648 111.004 104.165 1.00 104.50 ? 323 ASN A ND2   1 
ATOM   2431 N N     . GLU A 1 324 ? 103.457 109.200 103.778 1.00 82.32  ? 324 GLU A N     1 
ATOM   2432 C CA    . GLU A 1 324 ? 102.096 109.308 103.278 1.00 82.32  ? 324 GLU A CA    1 
ATOM   2433 C C     . GLU A 1 324 ? 101.102 109.278 104.416 1.00 82.32  ? 324 GLU A C     1 
ATOM   2434 O O     . GLU A 1 324 ? 100.130 110.055 104.433 1.00 82.32  ? 324 GLU A O     1 
ATOM   2435 C CB    . GLU A 1 324 ? 101.768 108.216 102.294 1.00 110.57 ? 324 GLU A CB    1 
ATOM   2436 C CG    . GLU A 1 324 ? 100.388 108.371 101.701 1.00 110.57 ? 324 GLU A CG    1 
ATOM   2437 C CD    . GLU A 1 324 ? 100.056 107.325 100.671 1.00 110.57 ? 324 GLU A CD    1 
ATOM   2438 O OE1   . GLU A 1 324 ? 100.937 106.552 100.309 1.00 110.57 ? 324 GLU A OE1   1 
ATOM   2439 O OE2   . GLU A 1 324 ? 98.900  107.258 100.238 1.00 110.57 ? 324 GLU A OE2   1 
ATOM   2440 N N     . ALA A 1 325 ? 101.324 108.411 105.395 1.00 84.20  ? 325 ALA A N     1 
ATOM   2441 C CA    . ALA A 1 325 ? 100.389 108.335 106.507 1.00 84.20  ? 325 ALA A CA    1 
ATOM   2442 C C     . ALA A 1 325 ? 100.351 109.633 107.292 1.00 84.20  ? 325 ALA A C     1 
ATOM   2443 O O     . ALA A 1 325 ? 99.279  110.098 107.703 1.00 84.20  ? 325 ALA A O     1 
ATOM   2444 C CB    . ALA A 1 325 ? 100.771 107.184 107.423 1.00 114.82 ? 325 ALA A CB    1 
ATOM   2445 N N     . MET A 1 326 ? 101.499 110.257 107.495 1.00 81.80  ? 326 MET A N     1 
ATOM   2446 C CA    . MET A 1 326 ? 101.471 111.467 108.280 1.00 81.80  ? 326 MET A CA    1 
ATOM   2447 C C     . MET A 1 326 ? 100.897 112.621 107.500 1.00 81.80  ? 326 MET A C     1 
ATOM   2448 O O     . MET A 1 326 ? 100.302 113.522 108.102 1.00 81.80  ? 326 MET A O     1 
ATOM   2449 C CB    . MET A 1 326 ? 102.846 111.792 108.839 1.00 117.48 ? 326 MET A CB    1 
ATOM   2450 C CG    . MET A 1 326 ? 103.336 110.748 109.833 1.00 117.48 ? 326 MET A CG    1 
ATOM   2451 S SD    . MET A 1 326 ? 102.106 110.222 111.052 1.00 117.48 ? 326 MET A SD    1 
ATOM   2452 C CE    . MET A 1 326 ? 101.698 111.725 111.887 1.00 117.48 ? 326 MET A CE    1 
ATOM   2453 N N     . ALA A 1 327 ? 101.027 112.622 106.183 1.00 81.17  ? 327 ALA A N     1 
ATOM   2454 C CA    . ALA A 1 327 ? 100.388 113.667 105.403 1.00 81.17  ? 327 ALA A CA    1 
ATOM   2455 C C     . ALA A 1 327 ? 98.895  113.614 105.584 1.00 81.17  ? 327 ALA A C     1 
ATOM   2456 O O     . ALA A 1 327 ? 98.240  114.658 105.711 1.00 81.17  ? 327 ALA A O     1 
ATOM   2457 C CB    . ALA A 1 327 ? 100.736 113.524 103.937 1.00 110.69 ? 327 ALA A CB    1 
ATOM   2458 N N     . THR A 1 328 ? 98.348  112.404 105.655 1.00 82.76  ? 328 THR A N     1 
ATOM   2459 C CA    . THR A 1 328 ? 96.920  112.249 105.904 1.00 82.76  ? 328 THR A CA    1 
ATOM   2460 C C     . THR A 1 328 ? 96.530  112.843 107.246 1.00 82.76  ? 328 THR A C     1 
ATOM   2461 O O     . THR A 1 328 ? 95.509  113.539 107.362 1.00 82.76  ? 328 THR A O     1 
ATOM   2462 C CB    . THR A 1 328 ? 96.513  110.782 105.867 1.00 115.85 ? 328 THR A CB    1 
ATOM   2463 O OG1   . THR A 1 328 ? 96.781  110.240 104.574 1.00 115.85 ? 328 THR A OG1   1 
ATOM   2464 C CG2   . THR A 1 328 ? 95.032  110.643 106.168 1.00 115.85 ? 328 THR A CG2   1 
ATOM   2465 N N     . VAL A 1 329 ? 97.342  112.592 108.269 1.00 86.97  ? 329 VAL A N     1 
ATOM   2466 C CA    . VAL A 1 329 ? 97.048  113.160 109.574 1.00 86.97  ? 329 VAL A CA    1 
ATOM   2467 C C     . VAL A 1 329 ? 97.037  114.676 109.530 1.00 86.97  ? 329 VAL A C     1 
ATOM   2468 O O     . VAL A 1 329 ? 96.164  115.309 110.130 1.00 86.97  ? 329 VAL A O     1 
ATOM   2469 C CB    . VAL A 1 329 ? 98.052  112.678 110.607 1.00 126.46 ? 329 VAL A CB    1 
ATOM   2470 C CG1   . VAL A 1 329 ? 97.866  113.430 111.909 1.00 126.46 ? 329 VAL A CG1   1 
ATOM   2471 C CG2   . VAL A 1 329 ? 97.894  111.198 110.822 1.00 126.46 ? 329 VAL A CG2   1 
ATOM   2472 N N     . LYS A 1 330 ? 98.018  115.287 108.872 1.00 80.43  ? 330 LYS A N     1 
ATOM   2473 C CA    . LYS A 1 330 ? 98.040  116.749 108.800 1.00 80.43  ? 330 LYS A CA    1 
ATOM   2474 C C     . LYS A 1 330 ? 96.798  117.283 108.138 1.00 80.43  ? 330 LYS A C     1 
ATOM   2475 O O     . LYS A 1 330 ? 96.273  118.314 108.553 1.00 80.43  ? 330 LYS A O     1 
ATOM   2476 C CB    . LYS A 1 330 ? 99.242  117.262 108.046 1.00 120.54 ? 330 LYS A CB    1 
ATOM   2477 C CG    . LYS A 1 330 ? 100.537 117.132 108.777 1.00 120.54 ? 330 LYS A CG    1 
ATOM   2478 C CD    . LYS A 1 330 ? 101.697 117.623 107.919 1.00 120.54 ? 330 LYS A CD    1 
ATOM   2479 C CE    . LYS A 1 330 ? 103.037 117.484 108.631 1.00 120.54 ? 330 LYS A CE    1 
ATOM   2480 N NZ    . LYS A 1 330 ? 104.183 117.897 107.764 1.00 120.54 ? 330 LYS A NZ    1 
ATOM   2481 N N     . GLU A 1 331 ? 96.308  116.612 107.124 1.00 82.37  ? 331 GLU A N     1 
ATOM   2482 C CA    . GLU A 1 331 ? 95.099  117.093 106.486 1.00 82.37  ? 331 GLU A CA    1 
ATOM   2483 C C     . GLU A 1 331 ? 93.894  116.997 107.390 1.00 82.37  ? 331 GLU A C     1 
ATOM   2484 O O     . GLU A 1 331 ? 93.030  117.872 107.370 1.00 82.37  ? 331 GLU A O     1 
ATOM   2485 C CB    . GLU A 1 331 ? 94.830  116.330 105.211 1.00 110.63 ? 331 GLU A CB    1 
ATOM   2486 C CG    . GLU A 1 331 ? 95.808  116.595 104.087 1.00 110.63 ? 331 GLU A CG    1 
ATOM   2487 C CD    . GLU A 1 331 ? 95.522  115.751 102.872 1.00 110.63 ? 331 GLU A CD    1 
ATOM   2488 O OE1   . GLU A 1 331 ? 94.645  114.888 102.950 1.00 110.63 ? 331 GLU A OE1   1 
ATOM   2489 O OE2   . GLU A 1 331 ? 96.171  115.948 101.844 1.00 110.63 ? 331 GLU A OE2   1 
ATOM   2490 N N     . GLN A 1 332 ? 93.796  115.929 108.168 1.00 84.66  ? 332 GLN A N     1 
ATOM   2491 C CA    . GLN A 1 332 ? 92.598  115.687 108.985 1.00 84.66  ? 332 GLN A CA    1 
ATOM   2492 C C     . GLN A 1 332 ? 92.561  116.411 110.327 1.00 84.66  ? 332 GLN A C     1 
ATOM   2493 O O     . GLN A 1 332 ? 91.486  116.764 110.789 1.00 84.66  ? 332 GLN A O     1 
ATOM   2494 C CB    . GLN A 1 332 ? 92.472  114.200 109.251 1.00 118.26 ? 332 GLN A CB    1 
ATOM   2495 C CG    . GLN A 1 332 ? 92.179  113.383 108.041 1.00 118.26 ? 332 GLN A CG    1 
ATOM   2496 C CD    . GLN A 1 332 ? 92.191  111.915 108.345 1.00 118.26 ? 332 GLN A CD    1 
ATOM   2497 O OE1   . GLN A 1 332 ? 92.637  111.494 109.408 1.00 118.26 ? 332 GLN A OE1   1 
ATOM   2498 N NE2   . GLN A 1 332 ? 91.701  111.116 107.408 1.00 118.26 ? 332 GLN A NE2   1 
ATOM   2499 N N     . ASN A 1 333 ? 93.687  116.622 110.985 1.00 85.76  ? 333 ASN A N     1 
ATOM   2500 C CA    . ASN A 1 333 ? 93.693  117.200 112.312 1.00 85.76  ? 333 ASN A CA    1 
ATOM   2501 C C     . ASN A 1 333 ? 94.400  118.539 112.338 1.00 85.76  ? 333 ASN A C     1 
ATOM   2502 O O     . ASN A 1 333 ? 95.610  118.617 112.126 1.00 85.76  ? 333 ASN A O     1 
ATOM   2503 C CB    . ASN A 1 333 ? 94.323  116.242 113.263 1.00 116.18 ? 333 ASN A CB    1 
ATOM   2504 C CG    . ASN A 1 333 ? 93.479  115.088 113.456 1.00 116.18 ? 333 ASN A CG    1 
ATOM   2505 O OD1   . ASN A 1 333 ? 92.420  115.189 114.071 1.00 116.18 ? 333 ASN A OD1   1 
ATOM   2506 N ND2   . ASN A 1 333 ? 93.890  113.954 112.927 1.00 116.18 ? 333 ASN A ND2   1 
ATOM   2507 N N     . SER A 1 334 ? 93.653  119.582 112.666 1.00 79.87  ? 334 SER A N     1 
ATOM   2508 C CA    . SER A 1 334 ? 94.160  120.939 112.616 1.00 79.87  ? 334 SER A CA    1 
ATOM   2509 C C     . SER A 1 334 ? 95.285  121.255 113.575 1.00 79.87  ? 334 SER A C     1 
ATOM   2510 O O     . SER A 1 334 ? 95.279  120.838 114.733 1.00 79.87  ? 334 SER A O     1 
ATOM   2511 C CB    . SER A 1 334 ? 93.044  121.878 112.901 1.00 107.58 ? 334 SER A CB    1 
ATOM   2512 O OG    . SER A 1 334 ? 92.080  121.798 111.882 1.00 107.58 ? 334 SER A OG    1 
ATOM   2513 N N     . PHE A 1 335 ? 96.219  122.063 113.091 1.00 84.57  ? 335 PHE A N     1 
ATOM   2514 C CA    . PHE A 1 335 ? 97.361  122.578 113.821 1.00 84.57  ? 335 PHE A CA    1 
ATOM   2515 C C     . PHE A 1 335 ? 97.353  124.096 113.796 1.00 84.57  ? 335 PHE A C     1 
ATOM   2516 O O     . PHE A 1 335 ? 96.828  124.719 112.881 1.00 84.57  ? 335 PHE A O     1 
ATOM   2517 C CB    . PHE A 1 335 ? 98.674  122.087 113.237 1.00 117.96 ? 335 PHE A CB    1 
ATOM   2518 C CG    . PHE A 1 335 ? 99.004  120.685 113.573 1.00 117.96 ? 335 PHE A CG    1 
ATOM   2519 C CD1   . PHE A 1 335 ? 98.418  119.653 112.948 1.00 117.96 ? 335 PHE A CD1   1 
ATOM   2520 C CD2   . PHE A 1 335 ? 99.954  120.411 114.516 1.00 117.96 ? 335 PHE A CD2   1 
ATOM   2521 C CE1   . PHE A 1 335 ? 98.738  118.379 113.257 1.00 117.96 ? 335 PHE A CE1   1 
ATOM   2522 C CE2   . PHE A 1 335 ? 100.275 119.128 114.835 1.00 117.96 ? 335 PHE A CE2   1 
ATOM   2523 C CZ    . PHE A 1 335 ? 99.662  118.116 114.215 1.00 117.96 ? 335 PHE A CZ    1 
ATOM   2524 N N     . VAL A 1 336 ? 97.938  124.669 114.804 1.00 82.40  ? 336 VAL A N     1 
ATOM   2525 C CA    . VAL A 1 336 ? 98.061  126.100 114.952 1.00 82.40  ? 336 VAL A CA    1 
ATOM   2526 C C     . VAL A 1 336 ? 99.169  126.562 114.034 1.00 82.40  ? 336 VAL A C     1 
ATOM   2527 O O     . VAL A 1 336 ? 100.303 126.124 114.190 1.00 82.40  ? 336 VAL A O     1 
ATOM   2528 C CB    . VAL A 1 336 ? 98.371  126.390 116.421 1.00 119.82 ? 336 VAL A CB    1 
ATOM   2529 C CG1   . VAL A 1 336 ? 98.663  127.822 116.704 1.00 119.82 ? 336 VAL A CG1   1 
ATOM   2530 C CG2   . VAL A 1 336 ? 97.177  125.922 117.267 1.00 119.82 ? 336 VAL A CG2   1 
ATOM   2531 N N     . ASN A 1 337 ? 98.894  127.501 113.119 1.00 81.30  ? 337 ASN A N     1 
ATOM   2532 C CA    . ASN A 1 337 ? 99.923  127.829 112.129 1.00 81.30  ? 337 ASN A CA    1 
ATOM   2533 C C     . ASN A 1 337 ? 101.000 128.735 112.637 1.00 81.30  ? 337 ASN A C     1 
ATOM   2534 O O     . ASN A 1 337 ? 101.890 129.075 111.880 1.00 81.30  ? 337 ASN A O     1 
ATOM   2535 C CB    . ASN A 1 337 ? 99.338  128.453 110.892 1.00 110.14 ? 337 ASN A CB    1 
ATOM   2536 C CG    . ASN A 1 337 ? 98.806  129.790 111.118 1.00 110.14 ? 337 ASN A CG    1 
ATOM   2537 O OD1   . ASN A 1 337 ? 99.024  130.417 112.144 1.00 110.14 ? 337 ASN A OD1   1 
ATOM   2538 N ND2   . ASN A 1 337 ? 98.079  130.271 110.143 1.00 110.14 ? 337 ASN A ND2   1 
ATOM   2539 N N     . TRP A 1 338 ? 100.938 129.149 113.871 1.00 85.98  ? 338 TRP A N     1 
ATOM   2540 C CA    . TRP A 1 338 ? 101.987 129.985 114.400 1.00 85.98  ? 338 TRP A CA    1 
ATOM   2541 C C     . TRP A 1 338 ? 103.243 129.247 114.401 1.00 85.98  ? 338 TRP A C     1 
ATOM   2542 O O     . TRP A 1 338 ? 104.318 129.836 114.511 1.00 85.98  ? 338 TRP A O     1 
ATOM   2543 C CB    . TRP A 1 338 ? 101.818 130.290 115.837 1.00 118.99 ? 338 TRP A CB    1 
ATOM   2544 C CG    . TRP A 1 338 ? 100.730 130.909 116.149 1.00 118.99 ? 338 TRP A CG    1 
ATOM   2545 C CD1   . TRP A 1 338 ? 99.978  131.680 115.387 1.00 118.99 ? 338 TRP A CD1   1 
ATOM   2546 C CD2   . TRP A 1 338 ? 100.162 130.830 117.366 1.00 118.99 ? 338 TRP A CD2   1 
ATOM   2547 N NE1   . TRP A 1 338 ? 98.942  132.113 116.087 1.00 118.99 ? 338 TRP A NE1   1 
ATOM   2548 C CE2   . TRP A 1 338 ? 99.040  131.578 117.328 1.00 118.99 ? 338 TRP A CE2   1 
ATOM   2549 C CE3   . TRP A 1 338 ? 100.502 130.167 118.512 1.00 118.99 ? 338 TRP A CE3   1 
ATOM   2550 C CZ2   . TRP A 1 338 ? 98.245  131.717 118.379 1.00 118.99 ? 338 TRP A CZ2   1 
ATOM   2551 C CZ3   . TRP A 1 338 ? 99.734  130.291 119.548 1.00 118.99 ? 338 TRP A CZ3   1 
ATOM   2552 C CH2   . TRP A 1 338 ? 98.606  131.060 119.497 1.00 118.99 ? 338 TRP A CH2   1 
ATOM   2553 N N     . ILE A 1 339 ? 103.117 127.948 114.493 1.00 79.82  ? 339 ILE A N     1 
ATOM   2554 C CA    . ILE A 1 339 ? 104.306 127.142 114.552 1.00 79.82  ? 339 ILE A CA    1 
ATOM   2555 C C     . ILE A 1 339 ? 104.351 126.433 113.210 1.00 79.82  ? 339 ILE A C     1 
ATOM   2556 O O     . ILE A 1 339 ? 103.520 125.563 112.961 1.00 79.82  ? 339 ILE A O     1 
ATOM   2557 C CB    . ILE A 1 339 ? 104.268 126.188 115.746 1.00 118.10 ? 339 ILE A CB    1 
ATOM   2558 C CG1   . ILE A 1 339 ? 104.047 126.990 117.027 1.00 118.10 ? 339 ILE A CG1   1 
ATOM   2559 C CG2   . ILE A 1 339 ? 105.610 125.533 115.842 1.00 118.10 ? 339 ILE A CG2   1 
ATOM   2560 C CD1   . ILE A 1 339 ? 103.745 126.199 118.255 1.00 118.10 ? 339 ILE A CD1   1 
ATOM   2561 N N     . PRO A 1 340 ? 105.234 126.845 112.304 1.00 74.46  ? 340 PRO A N     1 
ATOM   2562 C CA    . PRO A 1 340 ? 105.300 126.348 110.933 1.00 74.46  ? 340 PRO A CA    1 
ATOM   2563 C C     . PRO A 1 340 ? 105.894 124.986 110.875 1.00 74.46  ? 340 PRO A C     1 
ATOM   2564 O O     . PRO A 1 340 ? 105.946 124.336 109.823 1.00 74.46  ? 340 PRO A O     1 
ATOM   2565 C CB    . PRO A 1 340 ? 106.215 127.371 110.274 1.00 232.24 ? 340 PRO A CB    1 
ATOM   2566 C CG    . PRO A 1 340 ? 107.091 127.828 111.409 1.00 232.24 ? 340 PRO A CG    1 
ATOM   2567 C CD    . PRO A 1 340 ? 106.243 127.831 112.608 1.00 232.24 ? 340 PRO A CD    1 
ATOM   2568 N N     . THR A 1 341 ? 106.344 124.571 112.012 1.00 69.67  ? 341 THR A N     1 
ATOM   2569 C CA    . THR A 1 341 ? 107.002 123.349 112.329 1.00 69.67  ? 341 THR A CA    1 
ATOM   2570 C C     . THR A 1 341 ? 106.260 122.830 113.537 1.00 69.67  ? 341 THR A C     1 
ATOM   2571 O O     . THR A 1 341 ? 105.063 123.077 113.671 1.00 69.67  ? 341 THR A O     1 
ATOM   2572 C CB    . THR A 1 341 ? 108.462 123.605 112.592 1.00 97.52  ? 341 THR A CB    1 
ATOM   2573 O OG1   . THR A 1 341 ? 109.113 122.368 112.792 1.00 97.52  ? 341 THR A OG1   1 
ATOM   2574 C CG2   . THR A 1 341 ? 108.684 124.530 113.753 1.00 97.52  ? 341 THR A CG2   1 
ATOM   2575 N N     . GLY A 1 342 ? 106.862 122.035 114.361 1.00 77.44  ? 342 GLY A N     1 
ATOM   2576 C CA    . GLY A 1 342 ? 106.150 121.605 115.531 1.00 77.44  ? 342 GLY A CA    1 
ATOM   2577 C C     . GLY A 1 342 ? 105.524 120.247 115.423 1.00 77.44  ? 342 GLY A C     1 
ATOM   2578 O O     . GLY A 1 342 ? 105.031 119.732 116.426 1.00 77.44  ? 342 GLY A O     1 
ATOM   2579 N N     . PHE A 1 343 ? 105.548 119.643 114.270 1.00 76.91  ? 343 PHE A N     1 
ATOM   2580 C CA    . PHE A 1 343 ? 105.049 118.292 114.106 1.00 76.91  ? 343 PHE A CA    1 
ATOM   2581 C C     . PHE A 1 343 ? 106.227 117.448 113.711 1.00 76.91  ? 343 PHE A C     1 
ATOM   2582 O O     . PHE A 1 343 ? 106.641 117.468 112.552 1.00 76.91  ? 343 PHE A O     1 
ATOM   2583 C CB    . PHE A 1 343 ? 103.991 118.251 113.040 1.00 107.28 ? 343 PHE A CB    1 
ATOM   2584 C CG    . PHE A 1 343 ? 103.176 117.020 112.989 1.00 107.28 ? 343 PHE A CG    1 
ATOM   2585 C CD1   . PHE A 1 343 ? 103.366 115.959 113.788 1.00 107.28 ? 343 PHE A CD1   1 
ATOM   2586 C CD2   . PHE A 1 343 ? 102.143 116.984 112.120 1.00 107.28 ? 343 PHE A CD2   1 
ATOM   2587 C CE1   . PHE A 1 343 ? 102.546 114.904 113.714 1.00 107.28 ? 343 PHE A CE1   1 
ATOM   2588 C CE2   . PHE A 1 343 ? 101.327 115.925 112.056 1.00 107.28 ? 343 PHE A CE2   1 
ATOM   2589 C CZ    . PHE A 1 343 ? 101.532 114.892 112.858 1.00 107.28 ? 343 PHE A CZ    1 
ATOM   2590 N N     . LYS A 1 344 ? 106.803 116.754 114.658 1.00 76.90  ? 344 LYS A N     1 
ATOM   2591 C CA    . LYS A 1 344 ? 108.020 116.029 114.394 1.00 76.90  ? 344 LYS A CA    1 
ATOM   2592 C C     . LYS A 1 344 ? 107.775 114.541 114.330 1.00 76.90  ? 344 LYS A C     1 
ATOM   2593 O O     . LYS A 1 344 ? 107.124 113.965 115.201 1.00 76.90  ? 344 LYS A O     1 
ATOM   2594 C CB    . LYS A 1 344 ? 109.082 116.364 115.426 1.00 115.25 ? 344 LYS A CB    1 
ATOM   2595 C CG    . LYS A 1 344 ? 109.489 117.800 115.420 1.00 115.25 ? 344 LYS A CG    1 
ATOM   2596 C CD    . LYS A 1 344 ? 110.074 118.182 114.057 1.00 115.25 ? 344 LYS A CD    1 
ATOM   2597 C CE    . LYS A 1 344 ? 110.618 119.581 113.985 1.00 115.25 ? 344 LYS A CE    1 
ATOM   2598 N NZ    . LYS A 1 344 ? 110.957 119.917 112.572 1.00 115.25 ? 344 LYS A NZ    1 
ATOM   2599 N N     . ILE A 1 345 ? 108.262 113.931 113.271 1.00 71.90  ? 345 ILE A N     1 
ATOM   2600 C CA    . ILE A 1 345 ? 108.074 112.531 113.032 1.00 71.90  ? 345 ILE A CA    1 
ATOM   2601 C C     . ILE A 1 345 ? 109.407 111.876 113.136 1.00 71.90  ? 345 ILE A C     1 
ATOM   2602 O O     . ILE A 1 345 ? 110.374 112.360 112.560 1.00 71.90  ? 345 ILE A O     1 
ATOM   2603 C CB    . ILE A 1 345 ? 107.516 112.267 111.648 1.00 106.38 ? 345 ILE A CB    1 
ATOM   2604 C CG1   . ILE A 1 345 ? 106.309 113.155 111.382 1.00 106.38 ? 345 ILE A CG1   1 
ATOM   2605 C CG2   . ILE A 1 345 ? 107.184 110.827 111.520 1.00 106.38 ? 345 ILE A CG2   1 
ATOM   2606 C CD1   . ILE A 1 345 ? 105.159 113.003 112.325 1.00 106.38 ? 345 ILE A CD1   1 
ATOM   2607 N N     . SER A 1 346 ? 109.475 110.784 113.860 1.00 79.60  ? 346 SER A N     1 
ATOM   2608 C CA    . SER A 1 346 ? 110.732 110.090 114.005 1.00 79.60  ? 346 SER A CA    1 
ATOM   2609 C C     . SER A 1 346 ? 110.514 108.601 114.041 1.00 79.60  ? 346 SER A C     1 
ATOM   2610 O O     . SER A 1 346 ? 109.419 108.126 114.327 1.00 79.60  ? 346 SER A O     1 
ATOM   2611 C CB    . SER A 1 346 ? 111.434 110.501 115.259 1.00 107.21 ? 346 SER A CB    1 
ATOM   2612 O OG    . SER A 1 346 ? 110.716 110.060 116.370 1.00 107.21 ? 346 SER A OG    1 
ATOM   2613 N N     . LYS A 1 347 ? 111.564 107.854 113.741 1.00 82.13  ? 347 LYS A N     1 
ATOM   2614 C CA    . LYS A 1 347 ? 111.461 106.419 113.846 1.00 82.13  ? 347 LYS A CA    1 
ATOM   2615 C C     . LYS A 1 347 ? 112.676 105.839 114.528 1.00 82.13  ? 347 LYS A C     1 
ATOM   2616 O O     . LYS A 1 347 ? 113.721 106.469 114.623 1.00 82.13  ? 347 LYS A O     1 
ATOM   2617 C CB    . LYS A 1 347 ? 111.253 105.753 112.524 1.00 123.08 ? 347 LYS A CB    1 
ATOM   2618 C CG    . LYS A 1 347 ? 112.331 105.897 111.564 1.00 123.08 ? 347 LYS A CG    1 
ATOM   2619 C CD    . LYS A 1 347 ? 112.012 105.109 110.329 1.00 123.08 ? 347 LYS A CD    1 
ATOM   2620 C CE    . LYS A 1 347 ? 113.143 105.175 109.323 1.00 123.08 ? 347 LYS A CE    1 
ATOM   2621 N NZ    . LYS A 1 347 ? 112.874 104.306 108.160 1.00 123.08 ? 347 LYS A NZ    1 
ATOM   2622 N N     . SER A 1 348 ? 112.496 104.642 115.038 1.00 85.90  ? 348 SER A N     1 
ATOM   2623 C CA    . SER A 1 348 ? 113.560 103.891 115.645 1.00 85.90  ? 348 SER A CA    1 
ATOM   2624 C C     . SER A 1 348 ? 113.417 102.456 115.218 1.00 85.90  ? 348 SER A C     1 
ATOM   2625 O O     . SER A 1 348 ? 112.310 101.921 115.155 1.00 85.90  ? 348 SER A O     1 
ATOM   2626 C CB    . SER A 1 348 ? 113.568 103.955 117.141 1.00 115.70 ? 348 SER A CB    1 
ATOM   2627 O OG    . SER A 1 348 ? 114.562 103.071 117.626 1.00 115.70 ? 348 SER A OG    1 
ATOM   2628 N N     . GLU A 1 349 ? 114.548 101.838 114.929 1.00 91.32  ? 349 GLU A N     1 
ATOM   2629 C CA    . GLU A 1 349 ? 114.596 100.492 114.400 1.00 91.32  ? 349 GLU A CA    1 
ATOM   2630 C C     . GLU A 1 349 ? 114.219 99.434  115.402 1.00 91.32  ? 349 GLU A C     1 
ATOM   2631 O O     . GLU A 1 349 ? 114.002 98.291  115.005 1.00 91.32  ? 349 GLU A O     1 
ATOM   2632 C CB    . GLU A 1 349 ? 115.997 100.206 113.864 1.00 122.66 ? 349 GLU A CB    1 
ATOM   2633 C CG    . GLU A 1 349 ? 117.139 100.217 114.909 1.00 122.66 ? 349 GLU A CG    1 
ATOM   2634 C CD    . GLU A 1 349 ? 117.687 101.605 115.182 1.00 122.66 ? 349 GLU A CD    1 
ATOM   2635 O OE1   . GLU A 1 349 ? 117.019 102.572 114.822 1.00 122.66 ? 349 GLU A OE1   1 
ATOM   2636 O OE2   . GLU A 1 349 ? 118.770 101.735 115.758 1.00 122.66 ? 349 GLU A OE2   1 
ATOM   2637 N N     . THR A 1 350 ? 114.130 99.740  116.671 1.00 85.13  ? 350 THR A N     1 
ATOM   2638 C CA    . THR A 1 350 ? 113.796 98.703  117.615 1.00 85.13  ? 350 THR A CA    1 
ATOM   2639 C C     . THR A 1 350 ? 112.337 98.709  117.972 1.00 85.13  ? 350 THR A C     1 
ATOM   2640 O O     . THR A 1 350 ? 111.827 99.666  118.563 1.00 85.13  ? 350 THR A O     1 
ATOM   2641 C CB    . THR A 1 350 ? 114.638 98.800  118.858 1.00 119.17 ? 350 THR A CB    1 
ATOM   2642 O OG1   . THR A 1 350 ? 115.998 98.574  118.486 1.00 119.17 ? 350 THR A OG1   1 
ATOM   2643 C CG2   . THR A 1 350 ? 114.221 97.733  119.857 1.00 119.17 ? 350 THR A CG2   1 
ATOM   2644 N N     . SER A 1 351 ? 111.696 97.610  117.653 1.00 84.13  ? 351 SER A N     1 
ATOM   2645 C CA    . SER A 1 351 ? 110.299 97.366  117.850 1.00 84.13  ? 351 SER A CA    1 
ATOM   2646 C C     . SER A 1 351 ? 110.029 97.049  119.302 1.00 84.13  ? 351 SER A C     1 
ATOM   2647 O O     . SER A 1 351 ? 110.940 96.677  120.022 1.00 84.13  ? 351 SER A O     1 
ATOM   2648 C CB    . SER A 1 351 ? 109.896 96.204  116.972 1.00 113.32 ? 351 SER A CB    1 
ATOM   2649 O OG    . SER A 1 351 ? 110.557 95.051  117.389 1.00 113.32 ? 351 SER A OG    1 
ATOM   2650 N N     . PRO A 1 352 ? 108.803 97.233  119.758 1.00 84.90  ? 352 PRO A N     1 
ATOM   2651 C CA    . PRO A 1 352 ? 108.392 96.816  121.088 1.00 84.90  ? 352 PRO A CA    1 
ATOM   2652 C C     . PRO A 1 352 ? 108.295 95.307  121.114 1.00 84.90  ? 352 PRO A C     1 
ATOM   2653 O O     . PRO A 1 352 ? 108.106 94.681  120.080 1.00 84.90  ? 352 PRO A O     1 
ATOM   2654 C CB    . PRO A 1 352 ? 107.027 97.471  121.228 1.00 264.81 ? 352 PRO A CB    1 
ATOM   2655 C CG    . PRO A 1 352 ? 106.536 97.562  119.836 1.00 264.81 ? 352 PRO A CG    1 
ATOM   2656 C CD    . PRO A 1 352 ? 107.723 97.853  119.014 1.00 264.81 ? 352 PRO A CD    1 
ATOM   2657 N N     . LYS A 1 353 ? 108.362 94.704  122.297 1.00 86.90  ? 353 LYS A N     1 
ATOM   2658 C CA    . LYS A 1 353 ? 108.406 93.248  122.364 1.00 86.90  ? 353 LYS A CA    1 
ATOM   2659 C C     . LYS A 1 353 ? 107.165 92.556  121.839 1.00 86.90  ? 353 LYS A C     1 
ATOM   2660 O O     . LYS A 1 353 ? 107.255 91.422  121.377 1.00 86.90  ? 353 LYS A O     1 
ATOM   2661 C CB    . LYS A 1 353 ? 108.642 92.795  123.782 1.00 130.23 ? 353 LYS A CB    1 
ATOM   2662 C CG    . LYS A 1 353 ? 110.054 93.001  124.287 1.00 130.23 ? 353 LYS A CG    1 
ATOM   2663 C CD    . LYS A 1 353 ? 111.053 92.052  123.622 1.00 130.23 ? 353 LYS A CD    1 
ATOM   2664 C CE    . LYS A 1 353 ? 112.432 92.162  124.259 1.00 130.23 ? 353 LYS A CE    1 
ATOM   2665 N NZ    . LYS A 1 353 ? 113.428 91.248  123.639 1.00 130.23 ? 353 LYS A NZ    1 
ATOM   2666 N N     . ASP A 1 354 ? 106.015 93.182  121.875 1.00 90.57  ? 354 ASP A N     1 
ATOM   2667 C CA    . ASP A 1 354 ? 104.829 92.483  121.428 1.00 90.57  ? 354 ASP A CA    1 
ATOM   2668 C C     . ASP A 1 354 ? 104.392 92.799  120.001 1.00 90.57  ? 354 ASP A C     1 
ATOM   2669 O O     . ASP A 1 354 ? 103.300 92.382  119.620 1.00 90.57  ? 354 ASP A O     1 
ATOM   2670 C CB    . ASP A 1 354 ? 103.669 92.772  122.381 1.00 116.45 ? 354 ASP A CB    1 
ATOM   2671 C CG    . ASP A 1 354 ? 103.876 92.170  123.770 1.00 116.45 ? 354 ASP A CG    1 
ATOM   2672 O OD1   . ASP A 1 354 ? 104.388 91.044  123.884 1.00 116.45 ? 354 ASP A OD1   1 
ATOM   2673 O OD2   . ASP A 1 354 ? 103.531 92.836  124.753 1.00 116.45 ? 354 ASP A OD2   1 
ATOM   2674 N N     . SER A 1 355 ? 105.168 93.515  119.196 1.00 91.12  ? 355 SER A N     1 
ATOM   2675 C CA    . SER A 1 355 ? 104.640 93.712  117.851 1.00 91.12  ? 355 SER A CA    1 
ATOM   2676 C C     . SER A 1 355 ? 105.701 94.041  116.817 1.00 91.12  ? 355 SER A C     1 
ATOM   2677 O O     . SER A 1 355 ? 106.841 94.366  117.137 1.00 91.12  ? 355 SER A O     1 
ATOM   2678 C CB    . SER A 1 355 ? 103.574 94.806  117.831 1.00 122.73 ? 355 SER A CB    1 
ATOM   2679 O OG    . SER A 1 355 ? 104.110 96.078  118.124 1.00 122.73 ? 355 SER A OG    1 
ATOM   2680 N N     . ALA A 1 356 ? 105.298 93.951  115.563 1.00 90.10  ? 356 ALA A N     1 
ATOM   2681 C CA    . ALA A 1 356 ? 106.174 94.289  114.456 1.00 90.10  ? 356 ALA A CA    1 
ATOM   2682 C C     . ALA A 1 356 ? 106.409 95.771  114.358 1.00 90.10  ? 356 ALA A C     1 
ATOM   2683 O O     . ALA A 1 356 ? 107.479 96.203  113.921 1.00 90.10  ? 356 ALA A O     1 
ATOM   2684 C CB    . ALA A 1 356 ? 105.559 93.794  113.161 1.00 122.86 ? 356 ALA A CB    1 
ATOM   2685 N N     . LEU A 1 357 ? 105.392 96.564  114.675 1.00 86.11  ? 357 LEU A N     1 
ATOM   2686 C CA    . LEU A 1 357 ? 105.467 98.009  114.574 1.00 86.11  ? 357 LEU A CA    1 
ATOM   2687 C C     . LEU A 1 357 ? 104.540 98.639  115.580 1.00 86.11  ? 357 LEU A C     1 
ATOM   2688 O O     . LEU A 1 357 ? 103.374 98.268  115.630 1.00 86.11  ? 357 LEU A O     1 
ATOM   2689 C CB    . LEU A 1 357 ? 105.090 98.468  113.167 1.00 127.41 ? 357 LEU A CB    1 
ATOM   2690 C CG    . LEU A 1 357 ? 104.998 99.959  112.869 1.00 127.41 ? 357 LEU A CG    1 
ATOM   2691 C CD1   . LEU A 1 357 ? 106.356 100.614 112.976 1.00 127.41 ? 357 LEU A CD1   1 
ATOM   2692 C CD2   . LEU A 1 357 ? 104.398 100.170 111.495 1.00 127.41 ? 357 LEU A CD2   1 
ATOM   2693 N N     . GLY A 1 358 ? 105.019 99.605  116.343 1.00 79.61  ? 358 GLY A N     1 
ATOM   2694 C CA    . GLY A 1 358 ? 104.150 100.358 117.229 1.00 79.61  ? 358 GLY A CA    1 
ATOM   2695 C C     . GLY A 1 358 ? 104.292 101.852 117.046 1.00 79.61  ? 358 GLY A C     1 
ATOM   2696 O O     . GLY A 1 358 ? 105.340 102.343 116.662 1.00 79.61  ? 358 GLY A O     1 
ATOM   2697 N N     . VAL A 1 359 ? 103.242 102.587 117.360 1.00 78.16  ? 359 VAL A N     1 
ATOM   2698 C CA    . VAL A 1 359 ? 103.293 104.028 117.184 1.00 78.16  ? 359 VAL A CA    1 
ATOM   2699 C C     . VAL A 1 359 ? 102.870 104.791 118.414 1.00 78.16  ? 359 VAL A C     1 
ATOM   2700 O O     . VAL A 1 359 ? 101.840 104.502 119.032 1.00 78.16  ? 359 VAL A O     1 
ATOM   2701 C CB    . VAL A 1 359 ? 102.479 104.490 115.983 1.00 113.65 ? 359 VAL A CB    1 
ATOM   2702 C CG1   . VAL A 1 359 ? 102.462 106.006 115.897 1.00 113.65 ? 359 VAL A CG1   1 
ATOM   2703 C CG2   . VAL A 1 359 ? 103.159 104.012 114.787 1.00 113.65 ? 359 VAL A CG2   1 
ATOM   2704 N N     . ILE A 1 360 ? 103.659 105.785 118.748 1.00 80.37  ? 360 ILE A N     1 
ATOM   2705 C CA    . ILE A 1 360 ? 103.447 106.604 119.917 1.00 80.37  ? 360 ILE A CA    1 
ATOM   2706 C C     . ILE A 1 360 ? 103.297 108.052 119.585 1.00 80.37  ? 360 ILE A C     1 
ATOM   2707 O O     . ILE A 1 360 ? 104.191 108.641 118.977 1.00 80.37  ? 360 ILE A O     1 
ATOM   2708 C CB    . ILE A 1 360 ? 104.624 106.500 120.833 1.00 118.92 ? 360 ILE A CB    1 
ATOM   2709 C CG1   . ILE A 1 360 ? 104.778 105.075 121.155 1.00 118.92 ? 360 ILE A CG1   1 
ATOM   2710 C CG2   . ILE A 1 360 ? 104.446 107.317 122.012 1.00 118.92 ? 360 ILE A CG2   1 
ATOM   2711 C CD1   . ILE A 1 360 ? 105.852 104.350 120.310 1.00 118.92 ? 360 ILE A CD1   1 
ATOM   2712 N N     . MET A 1 361 ? 102.277 108.666 120.092 1.00 84.56  ? 361 MET A N     1 
ATOM   2713 C CA    . MET A 1 361 ? 102.141 110.086 119.864 1.00 84.56  ? 361 MET A CA    1 
ATOM   2714 C C     . MET A 1 361 ? 101.953 110.880 121.133 1.00 84.56  ? 361 MET A C     1 
ATOM   2715 O O     . MET A 1 361 ? 101.182 110.496 122.018 1.00 84.56  ? 361 MET A O     1 
ATOM   2716 C CB    . MET A 1 361 ? 101.016 110.341 118.959 1.00 121.44 ? 361 MET A CB    1 
ATOM   2717 C CG    . MET A 1 361 ? 100.724 111.755 118.653 1.00 121.44 ? 361 MET A CG    1 
ATOM   2718 S SD    . MET A 1 361 ? 99.628  112.503 119.806 1.00 121.44 ? 361 MET A SD    1 
ATOM   2719 C CE    . MET A 1 361 ? 98.062  111.901 119.245 1.00 121.44 ? 361 MET A CE    1 
ATOM   2720 N N     . LEU A 1 362 ? 102.654 111.991 121.193 1.00 75.67  ? 362 LEU A N     1 
ATOM   2721 C CA    . LEU A 1 362 ? 102.516 112.956 122.247 1.00 75.67  ? 362 LEU A CA    1 
ATOM   2722 C C     . LEU A 1 362 ? 102.080 114.257 121.662 1.00 75.67  ? 362 LEU A C     1 
ATOM   2723 O O     . LEU A 1 362 ? 102.482 114.599 120.556 1.00 75.67  ? 362 LEU A O     1 
ATOM   2724 C CB    . LEU A 1 362 ? 103.778 113.232 122.968 1.00 111.96 ? 362 LEU A CB    1 
ATOM   2725 C CG    . LEU A 1 362 ? 104.494 112.137 123.670 1.00 111.96 ? 362 LEU A CG    1 
ATOM   2726 C CD1   . LEU A 1 362 ? 105.792 112.704 124.215 1.00 111.96 ? 362 LEU A CD1   1 
ATOM   2727 C CD2   . LEU A 1 362 ? 103.623 111.605 124.770 1.00 111.96 ? 362 LEU A CD2   1 
ATOM   2728 N N     . GLY A 1 363 ? 101.350 115.049 122.423 1.00 81.96  ? 363 GLY A N     1 
ATOM   2729 C CA    . GLY A 1 363 ? 101.115 116.383 121.918 1.00 81.96  ? 363 GLY A CA    1 
ATOM   2730 C C     . GLY A 1 363 ? 100.299 117.324 122.766 1.00 81.96  ? 363 GLY A C     1 
ATOM   2731 O O     . GLY A 1 363 ? 99.700  116.963 123.779 1.00 81.96  ? 363 GLY A O     1 
ATOM   2732 N N     . ASN A 1 364 ? 100.312 118.549 122.334 1.00 87.54  ? 364 ASN A N     1 
ATOM   2733 C CA    . ASN A 1 364 ? 99.622  119.624 122.986 1.00 87.54  ? 364 ASN A CA    1 
ATOM   2734 C C     . ASN A 1 364 ? 98.408  119.916 122.172 1.00 87.54  ? 364 ASN A C     1 
ATOM   2735 O O     . ASN A 1 364 ? 98.518  120.514 121.098 1.00 87.54  ? 364 ASN A O     1 
ATOM   2736 C CB    . ASN A 1 364 ? 100.399 120.901 122.985 1.00 118.59 ? 364 ASN A CB    1 
ATOM   2737 C CG    . ASN A 1 364 ? 101.537 120.833 123.685 1.00 118.59 ? 364 ASN A CG    1 
ATOM   2738 O OD1   . ASN A 1 364 ? 101.560 120.977 124.886 1.00 118.59 ? 364 ASN A OD1   1 
ATOM   2739 N ND2   . ASN A 1 364 ? 102.588 120.657 122.974 1.00 118.59 ? 364 ASN A ND2   1 
ATOM   2740 N N     . ASN A 1 365 ? 97.266  119.581 122.695 1.00 87.77  ? 365 ASN A N     1 
ATOM   2741 C CA    . ASN A 1 365 ? 96.024  119.788 122.007 1.00 87.77  ? 365 ASN A CA    1 
ATOM   2742 C C     . ASN A 1 365 ? 95.128  120.559 122.918 1.00 87.77  ? 365 ASN A C     1 
ATOM   2743 O O     . ASN A 1 365 ? 95.048  120.278 124.108 1.00 87.77  ? 365 ASN A O     1 
ATOM   2744 C CB    . ASN A 1 365 ? 95.416  118.512 121.618 1.00 118.90 ? 365 ASN A CB    1 
ATOM   2745 C CG    . ASN A 1 365 ? 94.196  118.669 120.808 1.00 118.90 ? 365 ASN A CG    1 
ATOM   2746 O OD1   . ASN A 1 365 ? 93.196  119.229 121.236 1.00 118.90 ? 365 ASN A OD1   1 
ATOM   2747 N ND2   . ASN A 1 365 ? 94.233  118.118 119.625 1.00 118.90 ? 365 ASN A ND2   1 
ATOM   2748 N N     . SER A 1 366 ? 94.475  121.537 122.376 1.00 92.57  ? 366 SER A N     1 
ATOM   2749 C CA    . SER A 1 366 ? 93.668  122.420 123.192 1.00 92.57  ? 366 SER A CA    1 
ATOM   2750 C C     . SER A 1 366 ? 92.534  121.729 123.916 1.00 92.57  ? 366 SER A C     1 
ATOM   2751 O O     . SER A 1 366 ? 92.063  122.248 124.933 1.00 92.57  ? 366 SER A O     1 
ATOM   2752 C CB    . SER A 1 366 ? 93.119  123.492 122.299 1.00 124.68 ? 366 SER A CB    1 
ATOM   2753 O OG    . SER A 1 366 ? 92.291  122.929 121.302 1.00 124.68 ? 366 SER A OG    1 
ATOM   2754 N N     . GLU A 1 367 ? 92.126  120.551 123.500 1.00 90.12  ? 367 GLU A N     1 
ATOM   2755 C CA    . GLU A 1 367 ? 91.053  119.865 124.194 1.00 90.12  ? 367 GLU A CA    1 
ATOM   2756 C C     . GLU A 1 367 ? 91.540  119.169 125.433 1.00 90.12  ? 367 GLU A C     1 
ATOM   2757 O O     . GLU A 1 367 ? 90.743  118.539 126.130 1.00 90.12  ? 367 GLU A O     1 
ATOM   2758 C CB    . GLU A 1 367 ? 90.374  118.834 123.330 1.00 121.04 ? 367 GLU A CB    1 
ATOM   2759 C CG    . GLU A 1 367 ? 89.731  119.325 122.101 1.00 121.04 ? 367 GLU A CG    1 
ATOM   2760 C CD    . GLU A 1 367 ? 88.600  120.251 122.337 1.00 121.04 ? 367 GLU A CD    1 
ATOM   2761 O OE1   . GLU A 1 367 ? 88.189  120.427 123.476 1.00 121.04 ? 367 GLU A OE1   1 
ATOM   2762 O OE2   . GLU A 1 367 ? 88.096  120.803 121.356 1.00 121.04 ? 367 GLU A OE2   1 
ATOM   2763 N N     . ILE A 1 368 ? 92.821  119.258 125.748 1.00 89.49  ? 368 ILE A N     1 
ATOM   2764 C CA    . ILE A 1 368 ? 93.311  118.603 126.937 1.00 89.49  ? 368 ILE A CA    1 
ATOM   2765 C C     . ILE A 1 368 ? 92.639  119.160 128.133 1.00 89.49  ? 368 ILE A C     1 
ATOM   2766 O O     . ILE A 1 368 ? 92.523  118.483 129.154 1.00 89.49  ? 368 ILE A O     1 
ATOM   2767 C CB    . ILE A 1 368 ? 94.804  118.756 127.086 1.00 132.41 ? 368 ILE A CB    1 
ATOM   2768 C CG1   . ILE A 1 368 ? 95.297  117.730 128.071 1.00 132.41 ? 368 ILE A CG1   1 
ATOM   2769 C CG2   . ILE A 1 368 ? 95.173  120.182 127.501 1.00 132.41 ? 368 ILE A CG2   1 
ATOM   2770 C CD1   . ILE A 1 368 ? 96.778  117.556 128.073 1.00 132.41 ? 368 ILE A CD1   1 
ATOM   2771 N N     . VAL A 1 369 ? 92.149  120.382 128.034 1.00 92.64  ? 369 VAL A N     1 
ATOM   2772 C CA    . VAL A 1 369 ? 91.504  121.010 129.155 1.00 92.64  ? 369 VAL A CA    1 
ATOM   2773 C C     . VAL A 1 369 ? 90.211  120.350 129.552 1.00 92.64  ? 369 VAL A C     1 
ATOM   2774 O O     . VAL A 1 369 ? 89.705  120.651 130.621 1.00 92.64  ? 369 VAL A O     1 
ATOM   2775 C CB    . VAL A 1 369 ? 91.201  122.478 128.882 1.00 134.70 ? 369 VAL A CB    1 
ATOM   2776 C CG1   . VAL A 1 369 ? 92.474  123.201 128.586 1.00 134.70 ? 369 VAL A CG1   1 
ATOM   2777 C CG2   . VAL A 1 369 ? 90.224  122.600 127.792 1.00 134.70 ? 369 VAL A CG2   1 
ATOM   2778 N N     . SER A 1 370 ? 89.661  119.456 128.753 1.00 93.19  ? 370 SER A N     1 
ATOM   2779 C CA    . SER A 1 370 ? 88.438  118.797 129.187 1.00 93.19  ? 370 SER A CA    1 
ATOM   2780 C C     . SER A 1 370 ? 88.635  118.104 130.502 1.00 93.19  ? 370 SER A C     1 
ATOM   2781 O O     . SER A 1 370 ? 87.709  118.015 131.303 1.00 93.19  ? 370 SER A O     1 
ATOM   2782 C CB    . SER A 1 370 ? 88.018  117.742 128.212 1.00 125.52 ? 370 SER A CB    1 
ATOM   2783 O OG    . SER A 1 370 ? 88.935  116.668 128.317 1.00 125.52 ? 370 SER A OG    1 
ATOM   2784 N N     . VAL A 1 371 ? 89.829  117.609 130.759 1.00 96.37  ? 371 VAL A N     1 
ATOM   2785 C CA    . VAL A 1 371 ? 90.076  116.952 132.019 1.00 96.37  ? 371 VAL A CA    1 
ATOM   2786 C C     . VAL A 1 371 ? 89.983  117.962 133.137 1.00 96.37  ? 371 VAL A C     1 
ATOM   2787 O O     . VAL A 1 371 ? 89.288  117.758 134.145 1.00 96.37  ? 371 VAL A O     1 
ATOM   2788 C CB    . VAL A 1 371 ? 91.452  116.271 131.992 1.00 140.13 ? 371 VAL A CB    1 
ATOM   2789 C CG1   . VAL A 1 371 ? 91.823  115.700 133.360 1.00 140.13 ? 371 VAL A CG1   1 
ATOM   2790 C CG2   . VAL A 1 371 ? 91.459  115.198 130.933 1.00 140.13 ? 371 VAL A CG2   1 
ATOM   2791 N N     . PHE A 1 372 ? 90.648  119.086 132.944 1.00 95.07  ? 372 PHE A N     1 
ATOM   2792 C CA    . PHE A 1 372 ? 90.709  120.112 133.949 1.00 95.07  ? 372 PHE A CA    1 
ATOM   2793 C C     . PHE A 1 372 ? 89.355  120.734 134.175 1.00 95.07  ? 372 PHE A C     1 
ATOM   2794 O O     . PHE A 1 372 ? 89.000  121.055 135.311 1.00 95.07  ? 372 PHE A O     1 
ATOM   2795 C CB    . PHE A 1 372 ? 91.699  121.159 133.525 1.00 132.61 ? 372 PHE A CB    1 
ATOM   2796 C CG    . PHE A 1 372 ? 93.040  120.631 133.226 1.00 132.61 ? 372 PHE A CG    1 
ATOM   2797 C CD1   . PHE A 1 372 ? 93.476  119.422 133.726 1.00 132.61 ? 372 PHE A CD1   1 
ATOM   2798 C CD2   . PHE A 1 372 ? 93.866  121.331 132.432 1.00 132.61 ? 372 PHE A CD2   1 
ATOM   2799 C CE1   . PHE A 1 372 ? 94.715  118.952 133.407 1.00 132.61 ? 372 PHE A CE1   1 
ATOM   2800 C CE2   . PHE A 1 372 ? 95.089  120.875 132.122 1.00 132.61 ? 372 PHE A CE2   1 
ATOM   2801 C CZ    . PHE A 1 372 ? 95.515  119.681 132.600 1.00 132.61 ? 372 PHE A CZ    1 
ATOM   2802 N N     . GLU A 1 373 ? 88.583  120.899 133.120 1.00 101.05 ? 373 GLU A N     1 
ATOM   2803 C CA    . GLU A 1 373 ? 87.258  121.465 133.261 1.00 101.05 ? 373 GLU A CA    1 
ATOM   2804 C C     . GLU A 1 373 ? 86.341  120.569 134.073 1.00 101.05 ? 373 GLU A C     1 
ATOM   2805 O O     . GLU A 1 373 ? 85.583  121.065 134.909 1.00 101.05 ? 373 GLU A O     1 
ATOM   2806 C CB    . GLU A 1 373 ? 86.646  121.737 131.903 1.00 135.72 ? 373 GLU A CB    1 
ATOM   2807 C CG    . GLU A 1 373 ? 87.264  122.882 131.113 1.00 135.72 ? 373 GLU A CG    1 
ATOM   2808 C CD    . GLU A 1 373 ? 86.679  122.953 129.737 1.00 135.72 ? 373 GLU A CD    1 
ATOM   2809 O OE1   . GLU A 1 373 ? 85.898  122.057 129.415 1.00 135.72 ? 373 GLU A OE1   1 
ATOM   2810 O OE2   . GLU A 1 373 ? 86.994  123.868 128.974 1.00 135.72 ? 373 GLU A OE2   1 
ATOM   2811 N N     . ARG A 1 374 ? 86.397  119.258 133.872 1.00 101.25 ? 374 ARG A N     1 
ATOM   2812 C CA    . ARG A 1 374 ? 85.570  118.378 134.679 1.00 101.25 ? 374 ARG A CA    1 
ATOM   2813 C C     . ARG A 1 374 ? 85.971  118.440 136.127 1.00 101.25 ? 374 ARG A C     1 
ATOM   2814 O O     . ARG A 1 374 ? 85.113  118.447 137.015 1.00 101.25 ? 374 ARG A O     1 
ATOM   2815 C CB    . ARG A 1 374 ? 85.662  116.942 134.216 1.00 148.65 ? 374 ARG A CB    1 
ATOM   2816 C CG    . ARG A 1 374 ? 85.015  116.646 132.900 1.00 148.65 ? 374 ARG A CG    1 
ATOM   2817 C CD    . ARG A 1 374 ? 85.020  115.169 132.649 1.00 148.65 ? 374 ARG A CD    1 
ATOM   2818 N NE    . ARG A 1 374 ? 84.606  114.839 131.291 1.00 148.65 ? 374 ARG A NE    1 
ATOM   2819 C CZ    . ARG A 1 374 ? 85.442  114.687 130.267 1.00 148.65 ? 374 ARG A CZ    1 
ATOM   2820 N NH1   . ARG A 1 374 ? 86.745  114.854 130.411 1.00 148.65 ? 374 ARG A NH1   1 
ATOM   2821 N NH2   . ARG A 1 374 ? 84.959  114.357 129.072 1.00 148.65 ? 374 ARG A NH2   1 
ATOM   2822 N N     . ILE A 1 375 ? 87.270  118.489 136.384 1.00 99.22  ? 375 ILE A N     1 
ATOM   2823 C CA    . ILE A 1 375 ? 87.730  118.571 137.755 1.00 99.22  ? 375 ILE A CA    1 
ATOM   2824 C C     . ILE A 1 375 ? 87.225  119.832 138.395 1.00 99.22  ? 375 ILE A C     1 
ATOM   2825 O O     . ILE A 1 375 ? 86.762  119.818 139.541 1.00 99.22  ? 375 ILE A O     1 
ATOM   2826 C CB    . ILE A 1 375 ? 89.247  118.519 137.824 1.00 146.81 ? 375 ILE A CB    1 
ATOM   2827 C CG1   . ILE A 1 375 ? 89.728  117.149 137.387 1.00 146.81 ? 375 ILE A CG1   1 
ATOM   2828 C CG2   . ILE A 1 375 ? 89.693  118.838 139.243 1.00 146.81 ? 375 ILE A CG2   1 
ATOM   2829 C CD1   . ILE A 1 375 ? 91.220  117.079 137.102 1.00 146.81 ? 375 ILE A CD1   1 
ATOM   2830 N N     . GLY A 1 376 ? 87.321  120.939 137.681 1.00 100.04 ? 376 GLY A N     1 
ATOM   2831 C CA    . GLY A 1 376 ? 86.824  122.188 138.202 1.00 100.04 ? 376 GLY A CA    1 
ATOM   2832 C C     . GLY A 1 376 ? 85.363  122.086 138.556 1.00 100.04 ? 376 GLY A C     1 
ATOM   2833 O O     . GLY A 1 376 ? 84.963  122.443 139.650 1.00 100.04 ? 376 GLY A O     1 
ATOM   2834 N N     . ALA A 1 377 ? 84.560  121.534 137.666 1.00 103.35 ? 377 ALA A N     1 
ATOM   2835 C CA    . ALA A 1 377 ? 83.140  121.437 137.968 1.00 103.35 ? 377 ALA A CA    1 
ATOM   2836 C C     . ALA A 1 377 ? 82.871  120.625 139.226 1.00 103.35 ? 377 ALA A C     1 
ATOM   2837 O O     . ALA A 1 377 ? 82.030  121.008 140.057 1.00 103.35 ? 377 ALA A O     1 
ATOM   2838 C CB    . ALA A 1 377 ? 82.406  120.828 136.793 1.00 140.93 ? 377 ALA A CB    1 
ATOM   2839 N N     . ASN A 1 378 ? 83.558  119.504 139.391 1.00 105.14 ? 378 ASN A N     1 
ATOM   2840 C CA    . ASN A 1 378 ? 83.304  118.703 140.573 1.00 105.14 ? 378 ASN A CA    1 
ATOM   2841 C C     . ASN A 1 378 ? 83.677  119.496 141.807 1.00 105.14 ? 378 ASN A C     1 
ATOM   2842 O O     . ASN A 1 378 ? 82.963  119.500 142.834 1.00 105.14 ? 378 ASN A O     1 
ATOM   2843 C CB    . ASN A 1 378 ? 84.119  117.424 140.542 1.00 142.44 ? 378 ASN A CB    1 
ATOM   2844 C CG    . ASN A 1 378 ? 83.687  116.440 139.487 1.00 142.44 ? 378 ASN A CG    1 
ATOM   2845 O OD1   . ASN A 1 378 ? 82.538  116.380 139.037 1.00 142.44 ? 378 ASN A OD1   1 
ATOM   2846 N ND2   . ASN A 1 378 ? 84.638  115.624 139.089 1.00 142.44 ? 378 ASN A ND2   1 
ATOM   2847 N N     . PHE A 1 379 ? 84.776  120.217 141.688 1.00 107.55 ? 379 PHE A N     1 
ATOM   2848 C CA    . PHE A 1 379 ? 85.264  121.022 142.774 1.00 107.55 ? 379 PHE A CA    1 
ATOM   2849 C C     . PHE A 1 379 ? 84.291  122.095 143.122 1.00 107.55 ? 379 PHE A C     1 
ATOM   2850 O O     . PHE A 1 379 ? 83.998  122.293 144.287 1.00 107.55 ? 379 PHE A O     1 
ATOM   2851 C CB    . PHE A 1 379 ? 86.577  121.629 142.406 1.00 150.02 ? 379 PHE A CB    1 
ATOM   2852 C CG    . PHE A 1 379 ? 87.066  122.588 143.359 1.00 150.02 ? 379 PHE A CG    1 
ATOM   2853 C CD1   . PHE A 1 379 ? 87.720  122.199 144.477 1.00 150.02 ? 379 PHE A CD1   1 
ATOM   2854 C CD2   . PHE A 1 379 ? 86.926  123.893 143.104 1.00 150.02 ? 379 PHE A CD2   1 
ATOM   2855 C CE1   . PHE A 1 379 ? 88.212  123.122 145.316 1.00 150.02 ? 379 PHE A CE1   1 
ATOM   2856 C CE2   . PHE A 1 379 ? 87.405  124.808 143.939 1.00 150.02 ? 379 PHE A CE2   1 
ATOM   2857 C CZ    . PHE A 1 379 ? 88.049  124.427 145.039 1.00 150.02 ? 379 PHE A CZ    1 
ATOM   2858 N N     . ASP A 1 380 ? 83.759  122.786 142.136 1.00 106.42 ? 380 ASP A N     1 
ATOM   2859 C CA    . ASP A 1 380 ? 82.863  123.889 142.432 1.00 106.42 ? 380 ASP A CA    1 
ATOM   2860 C C     . ASP A 1 380 ? 81.651  123.419 143.201 1.00 106.42 ? 380 ASP A C     1 
ATOM   2861 O O     . ASP A 1 380 ? 81.233  124.066 144.166 1.00 106.42 ? 380 ASP A O     1 
ATOM   2862 C CB    . ASP A 1 380 ? 82.417  124.561 141.146 1.00 136.82 ? 380 ASP A CB    1 
ATOM   2863 C CG    . ASP A 1 380 ? 83.509  125.349 140.507 1.00 136.82 ? 380 ASP A CG    1 
ATOM   2864 O OD1   . ASP A 1 380 ? 84.450  125.679 141.211 1.00 136.82 ? 380 ASP A OD1   1 
ATOM   2865 O OD2   . ASP A 1 380 ? 83.452  125.625 139.303 1.00 136.82 ? 380 ASP A OD2   1 
ATOM   2866 N N     . ARG A 1 381 ? 81.083  122.276 142.820 1.00 109.77 ? 381 ARG A N     1 
ATOM   2867 C CA    . ARG A 1 381 ? 79.881  121.850 143.526 1.00 109.77 ? 381 ARG A CA    1 
ATOM   2868 C C     . ARG A 1 381 ? 80.162  121.621 144.985 1.00 109.77 ? 381 ARG A C     1 
ATOM   2869 O O     . ARG A 1 381 ? 79.345  121.969 145.844 1.00 109.77 ? 381 ARG A O     1 
ATOM   2870 C CB    . ARG A 1 381 ? 79.310  120.592 142.930 1.00 161.16 ? 381 ARG A CB    1 
ATOM   2871 C CG    . ARG A 1 381 ? 78.717  120.809 141.586 1.00 161.16 ? 381 ARG A CG    1 
ATOM   2872 C CD    . ARG A 1 381 ? 77.919  119.636 141.163 1.00 161.16 ? 381 ARG A CD    1 
ATOM   2873 N NE    . ARG A 1 381 ? 78.721  118.424 141.163 1.00 161.16 ? 381 ARG A NE    1 
ATOM   2874 C CZ    . ARG A 1 381 ? 79.493  118.007 140.163 1.00 161.16 ? 381 ARG A CZ    1 
ATOM   2875 N NH1   . ARG A 1 381 ? 79.612  118.692 139.035 1.00 161.16 ? 381 ARG A NH1   1 
ATOM   2876 N NH2   . ARG A 1 381 ? 80.171  116.877 140.306 1.00 161.16 ? 381 ARG A NH2   1 
ATOM   2877 N N     . LEU A 1 382 ? 81.318  121.051 145.289 1.00 111.50 ? 382 LEU A N     1 
ATOM   2878 C CA    . LEU A 1 382 ? 81.655  120.824 146.692 1.00 111.50 ? 382 LEU A CA    1 
ATOM   2879 C C     . LEU A 1 382 ? 82.197  122.072 147.391 1.00 111.50 ? 382 LEU A C     1 
ATOM   2880 O O     . LEU A 1 382 ? 81.952  122.294 148.583 1.00 111.50 ? 382 LEU A O     1 
ATOM   2881 C CB    . LEU A 1 382 ? 82.687  119.715 146.781 1.00 164.98 ? 382 LEU A CB    1 
ATOM   2882 C CG    . LEU A 1 382 ? 82.265  118.337 146.304 1.00 164.98 ? 382 LEU A CG    1 
ATOM   2883 C CD1   . LEU A 1 382 ? 83.478  117.454 146.311 1.00 164.98 ? 382 LEU A CD1   1 
ATOM   2884 C CD2   . LEU A 1 382 ? 81.190  117.754 147.203 1.00 164.98 ? 382 LEU A CD2   1 
ATOM   2885 N N     . TRP A 1 383 ? 82.957  122.876 146.671 1.00 113.74 ? 383 TRP A N     1 
ATOM   2886 C CA    . TRP A 1 383 ? 83.657  123.995 147.268 1.00 113.74 ? 383 TRP A CA    1 
ATOM   2887 C C     . TRP A 1 383 ? 82.749  125.141 147.613 1.00 113.74 ? 383 TRP A C     1 
ATOM   2888 O O     . TRP A 1 383 ? 82.908  125.744 148.675 1.00 113.74 ? 383 TRP A O     1 
ATOM   2889 C CB    . TRP A 1 383 ? 84.762  124.495 146.374 1.00 157.41 ? 383 TRP A CB    1 
ATOM   2890 C CG    . TRP A 1 383 ? 85.332  125.742 146.904 1.00 157.41 ? 383 TRP A CG    1 
ATOM   2891 C CD1   . TRP A 1 383 ? 85.408  126.908 146.245 1.00 157.41 ? 383 TRP A CD1   1 
ATOM   2892 C CD2   . TRP A 1 383 ? 85.884  125.979 148.204 1.00 157.41 ? 383 TRP A CD2   1 
ATOM   2893 N NE1   . TRP A 1 383 ? 85.978  127.859 147.033 1.00 157.41 ? 383 TRP A NE1   1 
ATOM   2894 C CE2   . TRP A 1 383 ? 86.278  127.307 148.240 1.00 157.41 ? 383 TRP A CE2   1 
ATOM   2895 C CE3   . TRP A 1 383 ? 86.090  125.191 149.332 1.00 157.41 ? 383 TRP A CE3   1 
ATOM   2896 C CZ2   . TRP A 1 383 ? 86.845  127.877 149.349 1.00 157.41 ? 383 TRP A CZ2   1 
ATOM   2897 C CZ3   . TRP A 1 383 ? 86.654  125.761 150.436 1.00 157.41 ? 383 TRP A CZ3   1 
ATOM   2898 C CH2   . TRP A 1 383 ? 87.024  127.087 150.440 1.00 157.41 ? 383 TRP A CH2   1 
ATOM   2899 N N     . SER A 1 384 ? 81.783  125.461 146.772 1.00 111.55 ? 384 SER A N     1 
ATOM   2900 C CA    . SER A 1 384 ? 80.951  126.611 147.084 1.00 111.55 ? 384 SER A CA    1 
ATOM   2901 C C     . SER A 1 384 ? 80.167  126.411 148.372 1.00 111.55 ? 384 SER A C     1 
ATOM   2902 O O     . SER A 1 384 ? 79.700  127.374 148.977 1.00 111.55 ? 384 SER A O     1 
ATOM   2903 C CB    . SER A 1 384 ? 80.002  126.884 145.936 1.00 150.25 ? 384 SER A CB    1 
ATOM   2904 O OG    . SER A 1 384 ? 79.001  125.894 145.879 1.00 150.25 ? 384 SER A OG    1 
ATOM   2905 N N     . ARG A 1 385 ? 80.032  125.174 148.795 1.00 115.26 ? 385 ARG A N     1 
ATOM   2906 C CA    . ARG A 1 385 ? 79.324  124.787 149.983 1.00 115.26 ? 385 ARG A CA    1 
ATOM   2907 C C     . ARG A 1 385 ? 80.265  124.514 151.134 1.00 115.26 ? 385 ARG A C     1 
ATOM   2908 O O     . ARG A 1 385 ? 79.826  124.031 152.189 1.00 115.26 ? 385 ARG A O     1 
ATOM   2909 C CB    . ARG A 1 385 ? 78.503  123.557 149.689 1.00 169.22 ? 385 ARG A CB    1 
ATOM   2910 C CG    . ARG A 1 385 ? 77.401  123.799 148.722 1.00 169.22 ? 385 ARG A CG    1 
ATOM   2911 C CD    . ARG A 1 385 ? 76.765  122.526 148.322 1.00 169.22 ? 385 ARG A CD    1 
ATOM   2912 N NE    . ARG A 1 385 ? 75.559  122.745 147.548 1.00 169.22 ? 385 ARG A NE    1 
ATOM   2913 C CZ    . ARG A 1 385 ? 75.505  122.983 146.244 1.00 169.22 ? 385 ARG A CZ    1 
ATOM   2914 N NH1   . ARG A 1 385 ? 76.595  123.021 145.492 1.00 169.22 ? 385 ARG A NH1   1 
ATOM   2915 N NH2   . ARG A 1 385 ? 74.321  123.190 145.677 1.00 169.22 ? 385 ARG A NH2   1 
ATOM   2916 N N     . LYS A 1 386 ? 81.527  124.880 150.978 1.00 114.53 ? 386 LYS A N     1 
ATOM   2917 C CA    . LYS A 1 386 ? 82.478  124.613 152.009 1.00 114.53 ? 386 LYS A CA    1 
ATOM   2918 C C     . LYS A 1 386 ? 82.260  123.180 152.415 1.00 114.53 ? 386 LYS A C     1 
ATOM   2919 O O     . LYS A 1 386 ? 81.914  122.879 153.550 1.00 114.53 ? 386 LYS A O     1 
ATOM   2920 C CB    . LYS A 1 386 ? 82.290  125.567 153.169 1.00 171.64 ? 386 LYS A CB    1 
ATOM   2921 C CG    . LYS A 1 386 ? 82.501  127.001 152.766 1.00 171.64 ? 386 LYS A CG    1 
ATOM   2922 C CD    . LYS A 1 386 ? 83.846  127.168 152.102 1.00 171.64 ? 386 LYS A CD    1 
ATOM   2923 C CE    . LYS A 1 386 ? 83.839  128.342 151.145 1.00 171.64 ? 386 LYS A CE    1 
ATOM   2924 N NZ    . LYS A 1 386 ? 82.913  128.108 150.000 1.00 171.64 ? 386 LYS A NZ    1 
ATOM   2925 N N     . ALA A 1 387 ? 82.389  122.304 151.425 1.00 119.31 ? 387 ALA A N     1 
ATOM   2926 C CA    . ALA A 1 387 ? 82.113  120.902 151.662 1.00 119.31 ? 387 ALA A CA    1 
ATOM   2927 C C     . ALA A 1 387 ? 82.986  120.389 152.761 1.00 119.31 ? 387 ALA A C     1 
ATOM   2928 O O     . ALA A 1 387 ? 82.523  119.693 153.660 1.00 119.31 ? 387 ALA A O     1 
ATOM   2929 C CB    . ALA A 1 387 ? 82.334  120.082 150.399 1.00 162.69 ? 387 ALA A CB    1 
ATOM   2930 N N     . PHE A 1 388 ? 84.249  120.716 152.716 1.00 121.96 ? 388 PHE A N     1 
ATOM   2931 C CA    . PHE A 1 388 ? 85.140  120.185 153.674 1.00 121.96 ? 388 PHE A CA    1 
ATOM   2932 C C     . PHE A 1 388 ? 86.163  121.221 154.061 1.00 121.96 ? 388 PHE A C     1 
ATOM   2933 O O     . PHE A 1 388 ? 87.348  121.044 153.827 1.00 121.96 ? 388 PHE A O     1 
ATOM   2934 C CB    . PHE A 1 388 ? 85.835  118.945 153.172 1.00 170.12 ? 388 PHE A CB    1 
ATOM   2935 C CG    . PHE A 1 388 ? 84.962  118.058 152.343 1.00 170.12 ? 388 PHE A CG    1 
ATOM   2936 C CD1   . PHE A 1 388 ? 84.040  117.207 152.938 1.00 170.12 ? 388 PHE A CD1   1 
ATOM   2937 C CD2   . PHE A 1 388 ? 85.064  118.063 150.961 1.00 170.12 ? 388 PHE A CD2   1 
ATOM   2938 C CE1   . PHE A 1 388 ? 83.232  116.383 152.172 1.00 170.12 ? 388 PHE A CE1   1 
ATOM   2939 C CE2   . PHE A 1 388 ? 84.261  117.239 150.193 1.00 170.12 ? 388 PHE A CE2   1 
ATOM   2940 C CZ    . PHE A 1 388 ? 83.344  116.398 150.806 1.00 170.12 ? 388 PHE A CZ    1 
ATOM   2941 N N     . ALA A 1 389 ? 85.707  122.337 154.590 1.00 125.42 ? 389 ALA A N     1 
ATOM   2942 C CA    . ALA A 1 389 ? 86.603  123.393 155.038 1.00 125.42 ? 389 ALA A CA    1 
ATOM   2943 C C     . ALA A 1 389 ? 87.541  122.958 156.166 1.00 125.42 ? 389 ALA A C     1 
ATOM   2944 O O     . ALA A 1 389 ? 88.761  122.956 155.987 1.00 125.42 ? 389 ALA A O     1 
ATOM   2945 C CB    . ALA A 1 389 ? 85.789  124.610 155.481 1.00 171.03 ? 389 ALA A CB    1 
ATOM   2946 N N     . HIS A 1 390 ? 87.004  122.621 157.344 1.00 125.72 ? 390 HIS A N     1 
ATOM   2947 C CA    . HIS A 1 390 ? 87.845  122.395 158.528 1.00 125.72 ? 390 HIS A CA    1 
ATOM   2948 C C     . HIS A 1 390 ? 88.749  121.201 158.452 1.00 125.72 ? 390 HIS A C     1 
ATOM   2949 O O     . HIS A 1 390 ? 89.680  121.085 159.279 1.00 125.72 ? 390 HIS A O     1 
ATOM   2950 C CB    . HIS A 1 390 ? 87.004  122.215 159.776 1.00 170.95 ? 390 HIS A CB    1 
ATOM   2951 C CG    . HIS A 1 390 ? 86.171  123.409 160.097 1.00 170.95 ? 390 HIS A CG    1 
ATOM   2952 N ND1   . HIS A 1 390 ? 86.678  124.516 160.742 1.00 170.95 ? 390 HIS A ND1   1 
ATOM   2953 C CD2   . HIS A 1 390 ? 84.869  123.681 159.848 1.00 170.95 ? 390 HIS A CD2   1 
ATOM   2954 C CE1   . HIS A 1 390 ? 85.721  125.415 160.885 1.00 170.95 ? 390 HIS A CE1   1 
ATOM   2955 N NE2   . HIS A 1 390 ? 84.613  124.933 160.352 1.00 170.95 ? 390 HIS A NE2   1 
ATOM   2956 N N     . TRP A 1 391 ? 88.410  120.253 157.596 1.00 125.49 ? 391 TRP A N     1 
ATOM   2957 C CA    . TRP A 1 391 ? 89.267  119.112 157.505 1.00 125.49 ? 391 TRP A CA    1 
ATOM   2958 C C     . TRP A 1 391 ? 90.544  119.671 157.062 1.00 125.49 ? 391 TRP A C     1 
ATOM   2959 O O     . TRP A 1 391 ? 91.556  119.618 157.754 1.00 125.49 ? 391 TRP A O     1 
ATOM   2960 C CB    . TRP A 1 391 ? 88.783  118.149 156.451 1.00 173.67 ? 391 TRP A CB    1 
ATOM   2961 C CG    . TRP A 1 391 ? 87.945  117.048 156.933 1.00 173.67 ? 391 TRP A CG    1 
ATOM   2962 C CD1   . TRP A 1 391 ? 86.903  117.130 157.799 1.00 173.67 ? 391 TRP A CD1   1 
ATOM   2963 C CD2   . TRP A 1 391 ? 88.046  115.677 156.547 1.00 173.67 ? 391 TRP A CD2   1 
ATOM   2964 N NE1   . TRP A 1 391 ? 86.354  115.888 157.993 1.00 173.67 ? 391 TRP A NE1   1 
ATOM   2965 C CE2   . TRP A 1 391 ? 87.040  114.979 157.232 1.00 173.67 ? 391 TRP A CE2   1 
ATOM   2966 C CE3   . TRP A 1 391 ? 88.897  114.970 155.697 1.00 173.67 ? 391 TRP A CE3   1 
ATOM   2967 C CZ2   . TRP A 1 391 ? 86.860  113.609 157.091 1.00 173.67 ? 391 TRP A CZ2   1 
ATOM   2968 C CZ3   . TRP A 1 391 ? 88.720  113.626 155.558 1.00 173.67 ? 391 TRP A CZ3   1 
ATOM   2969 C CH2   . TRP A 1 391 ? 87.711  112.951 156.249 1.00 173.67 ? 391 TRP A CH2   1 
ATOM   2970 N N     . PHE A 1 392 ? 90.461  120.328 155.925 1.00 126.70 ? 392 PHE A N     1 
ATOM   2971 C CA    . PHE A 1 392 ? 91.616  120.983 155.386 1.00 126.70 ? 392 PHE A CA    1 
ATOM   2972 C C     . PHE A 1 392 ? 92.061  122.113 156.286 1.00 126.70 ? 392 PHE A C     1 
ATOM   2973 O O     . PHE A 1 392 ? 93.257  122.414 156.323 1.00 126.70 ? 392 PHE A O     1 
ATOM   2974 C CB    . PHE A 1 392 ? 91.330  121.493 153.986 1.00 176.73 ? 392 PHE A CB    1 
ATOM   2975 C CG    . PHE A 1 392 ? 91.243  120.413 152.952 1.00 176.73 ? 392 PHE A CG    1 
ATOM   2976 C CD1   . PHE A 1 392 ? 90.032  119.805 152.665 1.00 176.73 ? 392 PHE A CD1   1 
ATOM   2977 C CD2   . PHE A 1 392 ? 92.366  120.010 152.258 1.00 176.73 ? 392 PHE A CD2   1 
ATOM   2978 C CE1   . PHE A 1 392 ? 89.950  118.810 151.709 1.00 176.73 ? 392 PHE A CE1   1 
ATOM   2979 C CE2   . PHE A 1 392 ? 92.296  119.026 151.300 1.00 176.73 ? 392 PHE A CE2   1 
ATOM   2980 C CZ    . PHE A 1 392 ? 91.087  118.419 151.025 1.00 176.73 ? 392 PHE A CZ    1 
ATOM   2981 N N     . THR A 1 393 ? 91.160  122.746 157.042 1.00 128.99 ? 393 THR A N     1 
ATOM   2982 C CA    . THR A 1 393 ? 91.680  123.834 157.876 1.00 128.99 ? 393 THR A CA    1 
ATOM   2983 C C     . THR A 1 393 ? 92.693  123.322 158.927 1.00 128.99 ? 393 THR A C     1 
ATOM   2984 O O     . THR A 1 393 ? 93.673  124.003 159.225 1.00 128.99 ? 393 THR A O     1 
ATOM   2985 C CB    . THR A 1 393 ? 90.583  124.647 158.581 1.00 180.56 ? 393 THR A CB    1 
ATOM   2986 O OG1   . THR A 1 393 ? 89.967  123.855 159.600 1.00 180.56 ? 393 THR A OG1   1 
ATOM   2987 C CG2   . THR A 1 393 ? 89.548  125.203 157.611 1.00 180.56 ? 393 THR A CG2   1 
ATOM   2988 N N     . ASP A 1 394 ? 92.495  122.141 159.508 1.00 130.47 ? 394 ASP A N     1 
ATOM   2989 C CA    . ASP A 1 394 ? 93.428  121.709 160.553 1.00 130.47 ? 394 ASP A CA    1 
ATOM   2990 C C     . ASP A 1 394 ? 94.643  120.964 160.043 1.00 130.47 ? 394 ASP A C     1 
ATOM   2991 O O     . ASP A 1 394 ? 95.486  120.527 160.826 1.00 130.47 ? 394 ASP A O     1 
ATOM   2992 C CB    . ASP A 1 394 ? 92.723  120.814 161.544 1.00 167.74 ? 394 ASP A CB    1 
ATOM   2993 C CG    . ASP A 1 394 ? 91.504  121.465 162.141 1.00 167.74 ? 394 ASP A CG    1 
ATOM   2994 O OD1   . ASP A 1 394 ? 91.209  122.623 161.778 1.00 167.74 ? 394 ASP A OD1   1 
ATOM   2995 O OD2   . ASP A 1 394 ? 90.835  120.823 162.977 1.00 167.74 ? 394 ASP A OD2   1 
ATOM   2996 N N     . SER A 1 395 ? 94.721  120.743 158.766 1.00 126.36 ? 395 SER A N     1 
ATOM   2997 C CA    . SER A 1 395 ? 95.866  120.076 158.206 1.00 126.36 ? 395 SER A CA    1 
ATOM   2998 C C     . SER A 1 395 ? 96.830  121.085 157.640 1.00 126.36 ? 395 SER A C     1 
ATOM   2999 O O     . SER A 1 395 ? 97.800  120.709 156.977 1.00 126.36 ? 395 SER A O     1 
ATOM   3000 C CB    . SER A 1 395 ? 95.425  119.093 157.134 1.00 170.20 ? 395 SER A CB    1 
ATOM   3001 O OG    . SER A 1 395 ? 94.593  118.092 157.671 1.00 170.20 ? 395 SER A OG    1 
ATOM   3002 N N     . GLY A 1 396 ? 96.564  122.363 157.866 1.00 123.40 ? 396 GLY A N     1 
ATOM   3003 C CA    . GLY A 1 396 ? 97.468  123.411 157.462 1.00 123.40 ? 396 GLY A CA    1 
ATOM   3004 C C     . GLY A 1 396 ? 97.174  124.176 156.187 1.00 123.40 ? 396 GLY A C     1 
ATOM   3005 O O     . GLY A 1 396 ? 98.011  124.983 155.783 1.00 123.40 ? 396 GLY A O     1 
ATOM   3006 N N     . PHE A 1 397 ? 96.044  123.981 155.534 1.00 122.52 ? 397 PHE A N     1 
ATOM   3007 C CA    . PHE A 1 397 ? 95.774  124.779 154.347 1.00 122.52 ? 397 PHE A CA    1 
ATOM   3008 C C     . PHE A 1 397 ? 94.659  125.769 154.618 1.00 122.52 ? 397 PHE A C     1 
ATOM   3009 O O     . PHE A 1 397 ? 93.697  125.453 155.316 1.00 122.52 ? 397 PHE A O     1 
ATOM   3010 C CB    . PHE A 1 397 ? 95.398  123.903 153.174 1.00 170.90 ? 397 PHE A CB    1 
ATOM   3011 C CG    . PHE A 1 397 ? 96.525  123.264 152.559 1.00 170.90 ? 397 PHE A CG    1 
ATOM   3012 C CD1   . PHE A 1 397 ? 97.009  122.103 153.048 1.00 170.90 ? 397 PHE A CD1   1 
ATOM   3013 C CD2   . PHE A 1 397 ? 97.113  123.825 151.479 1.00 170.90 ? 397 PHE A CD2   1 
ATOM   3014 C CE1   . PHE A 1 397 ? 98.076  121.512 152.461 1.00 170.90 ? 397 PHE A CE1   1 
ATOM   3015 C CE2   . PHE A 1 397 ? 98.162  123.245 150.886 1.00 170.90 ? 397 PHE A CE2   1 
ATOM   3016 C CZ    . PHE A 1 397 ? 98.648  122.084 151.373 1.00 170.90 ? 397 PHE A CZ    1 
ATOM   3017 N N     . GLU A 1 398 ? 94.768  126.962 154.071 1.00 118.32 ? 398 GLU A N     1 
ATOM   3018 C CA    . GLU A 1 398 ? 93.703  127.919 154.268 1.00 118.32 ? 398 GLU A CA    1 
ATOM   3019 C C     . GLU A 1 398 ? 92.855  128.015 153.015 1.00 118.32 ? 398 GLU A C     1 
ATOM   3020 O O     . GLU A 1 398 ? 93.259  127.594 151.933 1.00 118.32 ? 398 GLU A O     1 
ATOM   3021 C CB    . GLU A 1 398 ? 94.277  129.272 154.635 1.00 158.92 ? 398 GLU A CB    1 
ATOM   3022 C CG    . GLU A 1 398 ? 95.021  129.273 155.948 1.00 158.92 ? 398 GLU A CG    1 
ATOM   3023 C CD    . GLU A 1 398 ? 95.477  130.655 156.366 1.00 158.92 ? 398 GLU A CD    1 
ATOM   3024 O OE1   . GLU A 1 398 ? 94.919  131.636 155.872 1.00 158.92 ? 398 GLU A OE1   1 
ATOM   3025 O OE2   . GLU A 1 398 ? 96.393  130.758 157.185 1.00 158.92 ? 398 GLU A OE2   1 
ATOM   3026 N N     . GLU A 1 399 ? 91.680  128.592 153.158 1.00 113.12 ? 399 GLU A N     1 
ATOM   3027 C CA    . GLU A 1 399 ? 90.821  128.740 152.001 1.00 113.12 ? 399 GLU A CA    1 
ATOM   3028 C C     . GLU A 1 399 ? 91.517  129.540 150.914 1.00 113.12 ? 399 GLU A C     1 
ATOM   3029 O O     . GLU A 1 399 ? 91.361  129.244 149.730 1.00 113.12 ? 399 GLU A O     1 
ATOM   3030 C CB    . GLU A 1 399 ? 89.512  129.397 152.415 1.00 151.94 ? 399 GLU A CB    1 
ATOM   3031 C CG    . GLU A 1 399 ? 88.681  128.569 153.372 1.00 151.94 ? 399 GLU A CG    1 
ATOM   3032 C CD    . GLU A 1 399 ? 89.158  128.650 154.801 1.00 151.94 ? 399 GLU A CD    1 
ATOM   3033 O OE1   . GLU A 1 399 ? 90.103  129.394 155.069 1.00 151.94 ? 399 GLU A OE1   1 
ATOM   3034 O OE2   . GLU A 1 399 ? 88.597  127.958 155.651 1.00 151.94 ? 399 GLU A OE2   1 
ATOM   3035 N N     . LYS A 1 400 ? 92.336  130.508 151.288 1.00 109.17 ? 400 LYS A N     1 
ATOM   3036 C CA    . LYS A 1 400 ? 93.027  131.300 150.281 1.00 109.17 ? 400 LYS A CA    1 
ATOM   3037 C C     . LYS A 1 400 ? 93.980  130.474 149.452 1.00 109.17 ? 400 LYS A C     1 
ATOM   3038 O O     . LYS A 1 400 ? 94.290  130.849 148.321 1.00 109.17 ? 400 LYS A O     1 
ATOM   3039 C CB    . LYS A 1 400 ? 93.821  132.418 150.926 1.00 163.61 ? 400 LYS A CB    1 
ATOM   3040 C CG    . LYS A 1 400 ? 95.083  131.946 151.659 1.00 163.61 ? 400 LYS A CG    1 
ATOM   3041 C CD    . LYS A 1 400 ? 95.862  133.088 152.310 1.00 163.61 ? 400 LYS A CD    1 
ATOM   3042 C CE    . LYS A 1 400 ? 97.069  132.579 153.145 1.00 163.61 ? 400 LYS A CE    1 
ATOM   3043 N NZ    . LYS A 1 400 ? 98.185  131.954 152.329 1.00 163.61 ? 400 LYS A NZ    1 
ATOM   3044 N N     . ASP A 1 401 ? 94.449  129.350 149.974 1.00 112.66 ? 401 ASP A N     1 
ATOM   3045 C CA    . ASP A 1 401 ? 95.432  128.573 149.264 1.00 112.66 ? 401 ASP A CA    1 
ATOM   3046 C C     . ASP A 1 401 ? 94.754  127.679 148.278 1.00 112.66 ? 401 ASP A C     1 
ATOM   3047 O O     . ASP A 1 401 ? 95.270  127.441 147.180 1.00 112.66 ? 401 ASP A O     1 
ATOM   3048 C CB    . ASP A 1 401 ? 96.241  127.737 150.234 1.00 144.85 ? 401 ASP A CB    1 
ATOM   3049 C CG    . ASP A 1 401 ? 96.995  128.580 151.234 1.00 144.85 ? 401 ASP A CG    1 
ATOM   3050 O OD1   . ASP A 1 401 ? 97.666  129.546 150.837 1.00 144.85 ? 401 ASP A OD1   1 
ATOM   3051 O OD2   . ASP A 1 401 ? 96.910  128.278 152.432 1.00 144.85 ? 401 ASP A OD2   1 
ATOM   3052 N N     . LEU A 1 402 ? 93.600  127.193 148.635 1.00 110.50 ? 402 LEU A N     1 
ATOM   3053 C CA    . LEU A 1 402 ? 92.949  126.382 147.661 1.00 110.50 ? 402 LEU A CA    1 
ATOM   3054 C C     . LEU A 1 402 ? 92.343  127.282 146.605 1.00 110.50 ? 402 LEU A C     1 
ATOM   3055 O O     . LEU A 1 402 ? 92.232  126.880 145.441 1.00 110.50 ? 402 LEU A O     1 
ATOM   3056 C CB    . LEU A 1 402 ? 91.970  125.434 148.331 1.00 163.50 ? 402 LEU A CB    1 
ATOM   3057 C CG    . LEU A 1 402 ? 90.720  126.032 148.889 1.00 163.50 ? 402 LEU A CG    1 
ATOM   3058 C CD1   . LEU A 1 402 ? 89.640  125.978 147.874 1.00 163.50 ? 402 LEU A CD1   1 
ATOM   3059 C CD2   . LEU A 1 402 ? 90.336  125.289 150.091 1.00 163.50 ? 402 LEU A CD2   1 
ATOM   3060 N N     . ASP A 1 403 ? 92.015  128.512 146.963 1.00 108.12 ? 403 ASP A N     1 
ATOM   3061 C CA    . ASP A 1 403 ? 91.521  129.445 145.968 1.00 108.12 ? 403 ASP A CA    1 
ATOM   3062 C C     . ASP A 1 403 ? 92.626  129.821 145.019 1.00 108.12 ? 403 ASP A C     1 
ATOM   3063 O O     . ASP A 1 403 ? 92.390  129.974 143.824 1.00 108.12 ? 403 ASP A O     1 
ATOM   3064 C CB    . ASP A 1 403 ? 90.961  130.703 146.621 1.00 139.01 ? 403 ASP A CB    1 
ATOM   3065 C CG    . ASP A 1 403 ? 89.623  130.489 147.293 1.00 139.01 ? 403 ASP A CG    1 
ATOM   3066 O OD1   . ASP A 1 403 ? 88.898  129.566 146.928 1.00 139.01 ? 403 ASP A OD1   1 
ATOM   3067 O OD2   . ASP A 1 403 ? 89.295  131.272 148.187 1.00 139.01 ? 403 ASP A OD2   1 
ATOM   3068 N N     . ASP A 1 404 ? 93.839  129.966 145.527 1.00 102.45 ? 404 ASP A N     1 
ATOM   3069 C CA    . ASP A 1 404 ? 94.966  130.206 144.649 1.00 102.45 ? 404 ASP A CA    1 
ATOM   3070 C C     . ASP A 1 404 ? 95.132  129.051 143.704 1.00 102.45 ? 404 ASP A C     1 
ATOM   3071 O O     . ASP A 1 404 ? 95.396  129.243 142.509 1.00 102.45 ? 404 ASP A O     1 
ATOM   3072 C CB    . ASP A 1 404 ? 96.239  130.396 145.487 1.00 131.72 ? 404 ASP A CB    1 
ATOM   3073 C CG    . ASP A 1 404 ? 97.505  130.714 144.660 1.00 131.72 ? 404 ASP A CG    1 
ATOM   3074 O OD1   . ASP A 1 404 ? 97.583  131.794 144.064 1.00 131.72 ? 404 ASP A OD1   1 
ATOM   3075 O OD2   . ASP A 1 404 ? 98.436  129.884 144.653 1.00 131.72 ? 404 ASP A OD2   1 
ATOM   3076 N N     . ALA A 1 405 ? 94.980  127.841 144.214 1.00 99.19  ? 405 ALA A N     1 
ATOM   3077 C CA    . ALA A 1 405 ? 95.129  126.695 143.348 1.00 99.19  ? 405 ALA A CA    1 
ATOM   3078 C C     . ALA A 1 405 ? 94.101  126.734 142.243 1.00 99.19  ? 405 ALA A C     1 
ATOM   3079 O O     . ALA A 1 405 ? 94.430  126.514 141.067 1.00 99.19  ? 405 ALA A O     1 
ATOM   3080 C CB    . ALA A 1 405 ? 95.022  125.417 144.160 1.00 135.26 ? 405 ALA A CB    1 
ATOM   3081 N N     . ARG A 1 406 ? 92.869  127.093 142.565 1.00 97.96  ? 406 ARG A N     1 
ATOM   3082 C CA    . ARG A 1 406 ? 91.896  127.136 141.488 1.00 97.96  ? 406 ARG A CA    1 
ATOM   3083 C C     . ARG A 1 406 ? 92.169  128.261 140.537 1.00 97.96  ? 406 ARG A C     1 
ATOM   3084 O O     . ARG A 1 406 ? 91.996  128.098 139.336 1.00 97.96  ? 406 ARG A O     1 
ATOM   3085 C CB    . ARG A 1 406 ? 90.482  127.271 141.960 1.00 143.82 ? 406 ARG A CB    1 
ATOM   3086 C CG    . ARG A 1 406 ? 89.472  127.454 140.801 1.00 143.82 ? 406 ARG A CG    1 
ATOM   3087 C CD    . ARG A 1 406 ? 89.438  126.329 139.799 1.00 143.82 ? 406 ARG A CD    1 
ATOM   3088 N NE    . ARG A 1 406 ? 88.456  126.579 138.758 1.00 143.82 ? 406 ARG A NE    1 
ATOM   3089 C CZ    . ARG A 1 406 ? 87.184  126.338 138.931 1.00 143.82 ? 406 ARG A CZ    1 
ATOM   3090 N NH1   . ARG A 1 406 ? 86.755  125.897 140.063 1.00 143.82 ? 406 ARG A NH1   1 
ATOM   3091 N NH2   . ARG A 1 406 ? 86.335  126.570 137.955 1.00 143.82 ? 406 ARG A NH2   1 
ATOM   3092 N N     . ALA A 1 407 ? 92.561  129.408 141.032 1.00 94.57  ? 407 ALA A N     1 
ATOM   3093 C CA    . ALA A 1 407 ? 92.814  130.491 140.120 1.00 94.57  ? 407 ALA A CA    1 
ATOM   3094 C C     . ALA A 1 407 ? 93.856  130.104 139.101 1.00 94.57  ? 407 ALA A C     1 
ATOM   3095 O O     . ALA A 1 407 ? 93.724  130.422 137.923 1.00 94.57  ? 407 ALA A O     1 
ATOM   3096 C CB    . ALA A 1 407 ? 93.264  131.714 140.882 1.00 128.96 ? 407 ALA A CB    1 
ATOM   3097 N N     . LEU A 1 408 ? 94.894  129.417 139.529 1.00 91.05  ? 408 LEU A N     1 
ATOM   3098 C CA    . LEU A 1 408 ? 95.916  129.028 138.585 1.00 91.05  ? 408 LEU A CA    1 
ATOM   3099 C C     . LEU A 1 408 ? 95.386  128.029 137.601 1.00 91.05  ? 408 LEU A C     1 
ATOM   3100 O O     . LEU A 1 408 ? 95.703  128.100 136.406 1.00 91.05  ? 408 LEU A O     1 
ATOM   3101 C CB    . LEU A 1 408 ? 97.114  128.469 139.303 1.00 134.72 ? 408 LEU A CB    1 
ATOM   3102 C CG    . LEU A 1 408 ? 98.243  128.014 138.431 1.00 134.72 ? 408 LEU A CG    1 
ATOM   3103 C CD1   . LEU A 1 408 ? 98.775  129.146 137.591 1.00 134.72 ? 408 LEU A CD1   1 
ATOM   3104 C CD2   . LEU A 1 408 ? 99.309  127.476 139.289 1.00 134.72 ? 408 LEU A CD2   1 
ATOM   3105 N N     . VAL A 1 409 ? 94.602  127.072 138.067 1.00 95.29  ? 409 VAL A N     1 
ATOM   3106 C CA    . VAL A 1 409 ? 94.098  126.075 137.145 1.00 95.29  ? 409 VAL A CA    1 
ATOM   3107 C C     . VAL A 1 409 ? 93.218  126.724 136.128 1.00 95.29  ? 409 VAL A C     1 
ATOM   3108 O O     . VAL A 1 409 ? 93.262  126.385 134.940 1.00 95.29  ? 409 VAL A O     1 
ATOM   3109 C CB    . VAL A 1 409 ? 93.356  124.960 137.867 1.00 138.56 ? 409 VAL A CB    1 
ATOM   3110 C CG1   . VAL A 1 409 ? 92.635  124.085 136.864 1.00 138.56 ? 409 VAL A CG1   1 
ATOM   3111 C CG2   . VAL A 1 409 ? 94.321  124.154 138.659 1.00 138.56 ? 409 VAL A CG2   1 
ATOM   3112 N N     . GLN A 1 410 ? 92.391  127.645 136.562 1.00 95.03  ? 410 GLN A N     1 
ATOM   3113 C CA    . GLN A 1 410 ? 91.506  128.294 135.622 1.00 95.03  ? 410 GLN A CA    1 
ATOM   3114 C C     . GLN A 1 410 ? 92.304  129.092 134.637 1.00 95.03  ? 410 GLN A C     1 
ATOM   3115 O O     . GLN A 1 410 ? 91.979  129.096 133.455 1.00 95.03  ? 410 GLN A O     1 
ATOM   3116 C CB    . GLN A 1 410 ? 90.509  129.181 136.329 1.00 132.75 ? 410 GLN A CB    1 
ATOM   3117 C CG    . GLN A 1 410 ? 89.415  129.674 135.440 1.00 132.75 ? 410 GLN A CG    1 
ATOM   3118 C CD    . GLN A 1 410 ? 88.532  128.566 134.997 1.00 132.75 ? 410 GLN A CD    1 
ATOM   3119 O OE1   . GLN A 1 410 ? 88.154  127.696 135.792 1.00 132.75 ? 410 GLN A OE1   1 
ATOM   3120 N NE2   . GLN A 1 410 ? 88.194  128.559 133.716 1.00 132.75 ? 410 GLN A NE2   1 
ATOM   3121 N N     . LYS A 1 411 ? 93.386  129.730 135.073 1.00 96.47  ? 411 LYS A N     1 
ATOM   3122 C CA    . LYS A 1 411 ? 94.194  130.476 134.123 1.00 96.47  ? 411 LYS A CA    1 
ATOM   3123 C C     . LYS A 1 411 ? 94.705  129.577 133.038 1.00 96.47  ? 411 LYS A C     1 
ATOM   3124 O O     . LYS A 1 411 ? 94.635  129.934 131.868 1.00 96.47  ? 411 LYS A O     1 
ATOM   3125 C CB    . LYS A 1 411 ? 95.355  131.151 134.811 1.00 144.57 ? 411 LYS A CB    1 
ATOM   3126 C CG    . LYS A 1 411 ? 96.235  131.994 133.917 1.00 144.57 ? 411 LYS A CG    1 
ATOM   3127 C CD    . LYS A 1 411 ? 95.522  133.218 133.444 1.00 144.57 ? 411 LYS A CD    1 
ATOM   3128 C CE    . LYS A 1 411 ? 96.472  134.258 132.827 1.00 144.57 ? 411 LYS A CE    1 
ATOM   3129 N NZ    . LYS A 1 411 ? 97.023  133.862 131.479 1.00 144.57 ? 411 LYS A NZ    1 
ATOM   3130 N N     . VAL A 1 412 ? 95.164  128.383 133.385 1.00 93.36  ? 412 VAL A N     1 
ATOM   3131 C CA    . VAL A 1 412 ? 95.646  127.479 132.350 1.00 93.36  ? 412 VAL A CA    1 
ATOM   3132 C C     . VAL A 1 412 ? 94.535  127.094 131.403 1.00 93.36  ? 412 VAL A C     1 
ATOM   3133 O O     . VAL A 1 412 ? 94.742  127.048 130.193 1.00 93.36  ? 412 VAL A O     1 
ATOM   3134 C CB    . VAL A 1 412 ? 96.304  126.241 132.943 1.00 135.75 ? 412 VAL A CB    1 
ATOM   3135 C CG1   . VAL A 1 412 ? 96.583  125.217 131.887 1.00 135.75 ? 412 VAL A CG1   1 
ATOM   3136 C CG2   . VAL A 1 412 ? 97.581  126.659 133.554 1.00 135.75 ? 412 VAL A CG2   1 
ATOM   3137 N N     . ILE A 1 413 ? 93.353  126.796 131.924 1.00 93.04  ? 413 ILE A N     1 
ATOM   3138 C CA    . ILE A 1 413 ? 92.266  126.417 131.043 1.00 93.04  ? 413 ILE A CA    1 
ATOM   3139 C C     . ILE A 1 413 ? 91.961  127.536 130.107 1.00 93.04  ? 413 ILE A C     1 
ATOM   3140 O O     . ILE A 1 413 ? 91.778  127.334 128.907 1.00 93.04  ? 413 ILE A O     1 
ATOM   3141 C CB    . ILE A 1 413 ? 90.999  126.073 131.810 1.00 137.66 ? 413 ILE A CB    1 
ATOM   3142 C CG1   . ILE A 1 413 ? 91.190  124.809 132.632 1.00 137.66 ? 413 ILE A CG1   1 
ATOM   3143 C CG2   . ILE A 1 413 ? 89.854  125.912 130.836 1.00 137.66 ? 413 ILE A CG2   1 
ATOM   3144 C CD1   . ILE A 1 413 ? 90.085  124.556 133.655 1.00 137.66 ? 413 ILE A CD1   1 
ATOM   3145 N N     . ASP A 1 414 ? 91.846  128.727 130.647 1.00 99.19  ? 414 ASP A N     1 
ATOM   3146 C CA    . ASP A 1 414 ? 91.463  129.856 129.838 1.00 99.19  ? 414 ASP A CA    1 
ATOM   3147 C C     . ASP A 1 414 ? 92.514  130.126 128.791 1.00 99.19  ? 414 ASP A C     1 
ATOM   3148 O O     . ASP A 1 414 ? 92.181  130.453 127.655 1.00 99.19  ? 414 ASP A O     1 
ATOM   3149 C CB    . ASP A 1 414 ? 91.262  131.103 130.682 1.00 127.53 ? 414 ASP A CB    1 
ATOM   3150 C CG    . ASP A 1 414 ? 90.021  131.066 131.569 1.00 127.53 ? 414 ASP A CG    1 
ATOM   3151 O OD1   . ASP A 1 414 ? 89.154  130.203 131.421 1.00 127.53 ? 414 ASP A OD1   1 
ATOM   3152 O OD2   . ASP A 1 414 ? 89.919  131.941 132.431 1.00 127.53 ? 414 ASP A OD2   1 
ATOM   3153 N N     . ASP A 1 415 ? 93.786  130.000 129.143 1.00 98.81  ? 415 ASP A N     1 
ATOM   3154 C CA    . ASP A 1 415 ? 94.813  130.241 128.155 1.00 98.81  ? 415 ASP A CA    1 
ATOM   3155 C C     . ASP A 1 415 ? 94.761  129.201 127.069 1.00 98.81  ? 415 ASP A C     1 
ATOM   3156 O O     . ASP A 1 415 ? 94.877  129.539 125.905 1.00 98.81  ? 415 ASP A O     1 
ATOM   3157 C CB    . ASP A 1 415 ? 96.199  130.265 128.769 1.00 127.04 ? 415 ASP A CB    1 
ATOM   3158 C CG    . ASP A 1 415 ? 96.490  131.520 129.571 1.00 127.04 ? 415 ASP A CG    1 
ATOM   3159 O OD1   . ASP A 1 415 ? 95.760  132.509 129.489 1.00 127.04 ? 415 ASP A OD1   1 
ATOM   3160 O OD2   . ASP A 1 415 ? 97.486  131.527 130.307 1.00 127.04 ? 415 ASP A OD2   1 
ATOM   3161 N N     . TYR A 1 416 ? 94.544  127.940 127.378 1.00 92.86  ? 416 TYR A N     1 
ATOM   3162 C CA    . TYR A 1 416 ? 94.448  127.015 126.253 1.00 92.86  ? 416 TYR A CA    1 
ATOM   3163 C C     . TYR A 1 416 ? 93.294  127.373 125.333 1.00 92.86  ? 416 TYR A C     1 
ATOM   3164 O O     . TYR A 1 416 ? 93.450  127.353 124.111 1.00 92.86  ? 416 TYR A O     1 
ATOM   3165 C CB    . TYR A 1 416 ? 94.319  125.572 126.708 1.00 128.53 ? 416 TYR A CB    1 
ATOM   3166 C CG    . TYR A 1 416 ? 95.585  124.827 126.632 1.00 128.53 ? 416 TYR A CG    1 
ATOM   3167 C CD1   . TYR A 1 416 ? 96.087  124.583 125.436 1.00 128.53 ? 416 TYR A CD1   1 
ATOM   3168 C CD2   . TYR A 1 416 ? 96.260  124.384 127.734 1.00 128.53 ? 416 TYR A CD2   1 
ATOM   3169 C CE1   . TYR A 1 416 ? 97.216  123.932 125.276 1.00 128.53 ? 416 TYR A CE1   1 
ATOM   3170 C CE2   . TYR A 1 416 ? 97.437  123.706 127.582 1.00 128.53 ? 416 TYR A CE2   1 
ATOM   3171 C CZ    . TYR A 1 416 ? 97.905  123.500 126.334 1.00 128.53 ? 416 TYR A CZ    1 
ATOM   3172 O OH    . TYR A 1 416 ? 99.090  122.845 126.061 1.00 128.53 ? 416 TYR A OH    1 
ATOM   3173 N N     . ARG A 1 417 ? 92.137  127.715 125.879 1.00 95.78  ? 417 ARG A N     1 
ATOM   3174 C CA    . ARG A 1 417 ? 91.011  127.994 124.992 1.00 95.78  ? 417 ARG A CA    1 
ATOM   3175 C C     . ARG A 1 417 ? 91.255  129.225 124.157 1.00 95.78  ? 417 ARG A C     1 
ATOM   3176 O O     . ARG A 1 417 ? 90.908  129.243 122.983 1.00 95.78  ? 417 ARG A O     1 
ATOM   3177 C CB    . ARG A 1 417 ? 89.715  128.172 125.777 1.00 140.62 ? 417 ARG A CB    1 
ATOM   3178 C CG    . ARG A 1 417 ? 89.153  126.944 126.467 1.00 140.62 ? 417 ARG A CG    1 
ATOM   3179 C CD    . ARG A 1 417 ? 88.730  125.893 125.493 1.00 140.62 ? 417 ARG A CD    1 
ATOM   3180 N NE    . ARG A 1 417 ? 88.019  124.791 126.124 1.00 140.62 ? 417 ARG A NE    1 
ATOM   3181 C CZ    . ARG A 1 417 ? 87.740  123.625 125.553 1.00 140.62 ? 417 ARG A CZ    1 
ATOM   3182 N NH1   . ARG A 1 417 ? 88.111  123.342 124.316 1.00 140.62 ? 417 ARG A NH1   1 
ATOM   3183 N NH2   . ARG A 1 417 ? 87.076  122.717 126.250 1.00 140.62 ? 417 ARG A NH2   1 
ATOM   3184 N N     . LYS A 1 418 ? 91.831  130.273 124.740 1.00 97.02  ? 418 LYS A N     1 
ATOM   3185 C CA    . LYS A 1 418 ? 92.047  131.511 123.998 1.00 97.02  ? 418 LYS A CA    1 
ATOM   3186 C C     . LYS A 1 418 ? 93.228  131.423 123.071 1.00 97.02  ? 418 LYS A C     1 
ATOM   3187 O O     . LYS A 1 418 ? 93.171  131.895 121.940 1.00 97.02  ? 418 LYS A O     1 
ATOM   3188 C CB    . LYS A 1 418 ? 92.242  132.678 124.962 1.00 145.40 ? 418 LYS A CB    1 
ATOM   3189 C CG    . LYS A 1 418 ? 92.529  134.046 124.319 1.00 145.40 ? 418 LYS A CG    1 
ATOM   3190 C CD    . LYS A 1 418 ? 91.447  134.528 123.318 1.00 145.40 ? 418 LYS A CD    1 
ATOM   3191 C CE    . LYS A 1 418 ? 90.083  134.794 123.956 1.00 145.40 ? 418 LYS A CE    1 
ATOM   3192 N NZ    . LYS A 1 418 ? 89.125  135.392 122.968 1.00 145.40 ? 418 LYS A NZ    1 
ATOM   3193 N N     . LEU A 1 419 ? 94.292  130.810 123.520 1.00 93.52  ? 419 LEU A N     1 
ATOM   3194 C CA    . LEU A 1 419 ? 95.518  130.748 122.748 1.00 93.52  ? 419 LEU A CA    1 
ATOM   3195 C C     . LEU A 1 419 ? 95.287  130.114 121.402 1.00 93.52  ? 419 LEU A C     1 
ATOM   3196 O O     . LEU A 1 419 ? 95.785  130.598 120.386 1.00 93.52  ? 419 LEU A O     1 
ATOM   3197 C CB    . LEU A 1 419 ? 96.543  129.921 123.495 1.00 138.37 ? 419 LEU A CB    1 
ATOM   3198 C CG    . LEU A 1 419 ? 97.901  129.802 122.871 1.00 138.37 ? 419 LEU A CG    1 
ATOM   3199 C CD1   . LEU A 1 419 ? 98.599  131.138 122.936 1.00 138.37 ? 419 LEU A CD1   1 
ATOM   3200 C CD2   . LEU A 1 419 ? 98.631  128.780 123.632 1.00 138.37 ? 419 LEU A CD2   1 
ATOM   3201 N N     . THR A 1 420 ? 94.530  129.036 121.366 1.00 95.44  ? 420 THR A N     1 
ATOM   3202 C CA    . THR A 1 420 ? 94.337  128.333 120.129 1.00 95.44  ? 420 THR A CA    1 
ATOM   3203 C C     . THR A 1 420 ? 93.013  128.646 119.465 1.00 95.44  ? 420 THR A C     1 
ATOM   3204 O O     . THR A 1 420 ? 92.576  127.879 118.614 1.00 95.44  ? 420 THR A O     1 
ATOM   3205 C CB    . THR A 1 420 ? 94.451  126.849 120.370 1.00 133.60 ? 420 THR A CB    1 
ATOM   3206 O OG1   . THR A 1 420 ? 93.397  126.447 121.237 1.00 133.60 ? 420 THR A OG1   1 
ATOM   3207 C CG2   . THR A 1 420 ? 95.780  126.553 121.021 1.00 133.60 ? 420 THR A CG2   1 
ATOM   3208 N N     . GLU A 1 421 ? 92.346  129.738 119.841 1.00 99.77  ? 421 GLU A N     1 
ATOM   3209 C CA    . GLU A 1 421 ? 91.040  130.061 119.250 1.00 99.77  ? 421 GLU A CA    1 
ATOM   3210 C C     . GLU A 1 421 ? 91.121  130.264 117.745 1.00 99.77  ? 421 GLU A C     1 
ATOM   3211 O O     . GLU A 1 421 ? 90.177  129.935 117.022 1.00 99.77  ? 421 GLU A O     1 
ATOM   3212 C CB    . GLU A 1 421 ? 90.443  131.316 119.888 1.00 134.01 ? 421 GLU A CB    1 
ATOM   3213 C CG    . GLU A 1 421 ? 89.022  131.657 119.397 1.00 134.01 ? 421 GLU A CG    1 
ATOM   3214 C CD    . GLU A 1 421 ? 88.439  132.834 120.144 1.00 134.01 ? 421 GLU A CD    1 
ATOM   3215 O OE1   . GLU A 1 421 ? 89.211  133.569 120.760 1.00 134.01 ? 421 GLU A OE1   1 
ATOM   3216 O OE2   . GLU A 1 421 ? 87.223  133.020 120.127 1.00 134.01 ? 421 GLU A OE2   1 
ATOM   3217 N N     . ASP A 1 422 ? 92.220  130.836 117.262 1.00 99.98  ? 422 ASP A N     1 
ATOM   3218 C CA    . ASP A 1 422 ? 92.436  131.108 115.847 1.00 99.98  ? 422 ASP A CA    1 
ATOM   3219 C C     . ASP A 1 422 ? 93.895  130.750 115.535 1.00 99.98  ? 422 ASP A C     1 
ATOM   3220 O O     . ASP A 1 422 ? 94.633  130.377 116.447 1.00 99.98  ? 422 ASP A O     1 
ATOM   3221 C CB    . ASP A 1 422 ? 92.095  132.578 115.562 1.00 128.54 ? 422 ASP A CB    1 
ATOM   3222 C CG    . ASP A 1 422 ? 91.734  132.852 114.114 1.00 128.54 ? 422 ASP A CG    1 
ATOM   3223 O OD1   . ASP A 1 422 ? 92.107  132.064 113.247 1.00 128.54 ? 422 ASP A OD1   1 
ATOM   3224 O OD2   . ASP A 1 422 ? 91.094  133.875 113.845 1.00 128.54 ? 422 ASP A OD2   1 
ATOM   3225 N N     . ALA A 1 423 ? 94.302  130.876 114.250 1.00 96.86  ? 423 ALA A N     1 
ATOM   3226 C CA    . ALA A 1 423 ? 95.654  130.627 113.638 1.00 96.86  ? 423 ALA A CA    1 
ATOM   3227 C C     . ALA A 1 423 ? 95.518  129.731 112.390 1.00 96.86  ? 423 ALA A C     1 
ATOM   3228 O O     . ALA A 1 423 ? 96.129  128.658 112.272 1.00 96.86  ? 423 ALA A O     1 
ATOM   3229 C CB    . ALA A 1 423 ? 96.692  130.010 114.622 1.00 125.66 ? 423 ALA A CB    1 
ATOM   3230 O OXT   . ALA A 1 423 ? 94.868  130.137 111.422 1.00 135.08 ? 423 ALA A OXT   1 
ATOM   3231 N N     . ALA B 2 2   ? 154.175 126.127 102.938 1.00 85.97  ? 2   ALA D N     1 
ATOM   3232 C CA    . ALA B 2 2   ? 152.801 125.677 103.022 1.00 85.97  ? 2   ALA D CA    1 
ATOM   3233 C C     . ALA B 2 2   ? 151.964 126.661 103.831 1.00 85.97  ? 2   ALA D C     1 
ATOM   3234 O O     . ALA B 2 2   ? 152.353 127.024 104.939 1.00 85.97  ? 2   ALA D O     1 
ATOM   3235 C CB    . ALA B 2 2   ? 152.738 124.294 103.647 1.00 117.23 ? 2   ALA D CB    1 
ATOM   3236 N N     . ARG B 2 3   ? 150.827 127.098 103.270 1.00 88.93  ? 3   ARG D N     1 
ATOM   3237 C CA    . ARG B 2 3   ? 149.886 127.996 103.924 1.00 88.93  ? 3   ARG D CA    1 
ATOM   3238 C C     . ARG B 2 3   ? 148.775 127.140 104.486 1.00 88.93  ? 3   ARG D C     1 
ATOM   3239 O O     . ARG B 2 3   ? 147.998 126.553 103.733 1.00 88.93  ? 3   ARG D O     1 
ATOM   3240 C CB    . ARG B 2 3   ? 149.347 129.032 102.943 1.00 130.56 ? 3   ARG D CB    1 
ATOM   3241 C CG    . ARG B 2 3   ? 150.378 129.977 102.354 1.00 130.56 ? 3   ARG D CG    1 
ATOM   3242 C CD    . ARG B 2 3   ? 151.050 130.820 103.425 1.00 130.56 ? 3   ARG D CD    1 
ATOM   3243 N NE    . ARG B 2 3   ? 150.103 131.569 104.264 1.00 130.56 ? 3   ARG D NE    1 
ATOM   3244 C CZ    . ARG B 2 3   ? 149.601 132.773 103.981 1.00 130.56 ? 3   ARG D CZ    1 
ATOM   3245 N NH1   . ARG B 2 3   ? 149.915 133.405 102.863 1.00 130.56 ? 3   ARG D NH1   1 
ATOM   3246 N NH2   . ARG B 2 3   ? 148.764 133.356 104.843 1.00 130.56 ? 3   ARG D NH2   1 
ATOM   3247 N N     . GLU B 2 4   ? 148.705 127.058 105.803 1.00 87.54  ? 4   GLU D N     1 
ATOM   3248 C CA    . GLU B 2 4   ? 147.936 126.041 106.493 1.00 87.54  ? 4   GLU D CA    1 
ATOM   3249 C C     . GLU B 2 4   ? 146.584 126.450 107.050 1.00 87.54  ? 4   GLU D C     1 
ATOM   3250 O O     . GLU B 2 4   ? 146.354 127.605 107.417 1.00 87.54  ? 4   GLU D O     1 
ATOM   3251 C CB    . GLU B 2 4   ? 148.808 125.514 107.591 1.00 117.58 ? 4   GLU D CB    1 
ATOM   3252 C CG    . GLU B 2 4   ? 150.093 124.913 107.029 1.00 117.58 ? 4   GLU D CG    1 
ATOM   3253 C CD    . GLU B 2 4   ? 150.920 124.353 108.096 1.00 117.58 ? 4   GLU D CD    1 
ATOM   3254 O OE1   . GLU B 2 4   ? 150.420 124.365 109.207 1.00 117.58 ? 4   GLU D OE1   1 
ATOM   3255 O OE2   . GLU B 2 4   ? 152.061 123.949 107.869 1.00 117.58 ? 4   GLU D OE2   1 
ATOM   3256 N N     . VAL B 2 5   ? 145.700 125.482 107.185 1.00 85.41  ? 5   VAL D N     1 
ATOM   3257 C CA    . VAL B 2 5   ? 144.361 125.733 107.692 1.00 85.41  ? 5   VAL D CA    1 
ATOM   3258 C C     . VAL B 2 5   ? 143.997 124.863 108.889 1.00 85.41  ? 5   VAL D C     1 
ATOM   3259 O O     . VAL B 2 5   ? 144.192 123.654 108.867 1.00 85.41  ? 5   VAL D O     1 
ATOM   3260 C CB    . VAL B 2 5   ? 143.341 125.533 106.580 1.00 124.19 ? 5   VAL D CB    1 
ATOM   3261 C CG1   . VAL B 2 5   ? 141.969 125.714 107.116 1.00 124.19 ? 5   VAL D CG1   1 
ATOM   3262 C CG2   . VAL B 2 5   ? 143.595 126.546 105.502 1.00 124.19 ? 5   VAL D CG2   1 
ATOM   3263 N N     . ILE B 2 6   ? 143.446 125.479 109.931 1.00 84.49  ? 6   ILE D N     1 
ATOM   3264 C CA    . ILE B 2 6   ? 142.981 124.769 111.118 1.00 84.49  ? 6   ILE D CA    1 
ATOM   3265 C C     . ILE B 2 6   ? 141.507 124.527 110.972 1.00 84.49  ? 6   ILE D C     1 
ATOM   3266 O O     . ILE B 2 6   ? 140.768 125.441 110.630 1.00 84.49  ? 6   ILE D O     1 
ATOM   3267 C CB    . ILE B 2 6   ? 143.249 125.536 112.408 1.00 125.01 ? 6   ILE D CB    1 
ATOM   3268 C CG1   . ILE B 2 6   ? 144.724 125.675 112.626 1.00 125.01 ? 6   ILE D CG1   1 
ATOM   3269 C CG2   . ILE B 2 6   ? 142.609 124.814 113.573 1.00 125.01 ? 6   ILE D CG2   1 
ATOM   3270 C CD1   . ILE B 2 6   ? 145.127 126.641 113.669 1.00 125.01 ? 6   ILE D CD1   1 
ATOM   3271 N N     . THR B 2 7   ? 141.059 123.305 111.195 1.00 86.04  ? 7   THR D N     1 
ATOM   3272 C CA    . THR B 2 7   ? 139.650 122.974 111.039 1.00 86.04  ? 7   THR D CA    1 
ATOM   3273 C C     . THR B 2 7   ? 139.004 122.679 112.384 1.00 86.04  ? 7   THR D C     1 
ATOM   3274 O O     . THR B 2 7   ? 139.495 121.852 113.156 1.00 86.04  ? 7   THR D O     1 
ATOM   3275 C CB    . THR B 2 7   ? 139.457 121.785 110.118 1.00 120.44 ? 7   THR D CB    1 
ATOM   3276 O OG1   . THR B 2 7   ? 140.019 122.079 108.837 1.00 120.44 ? 7   THR D OG1   1 
ATOM   3277 C CG2   . THR B 2 7   ? 137.993 121.483 109.932 1.00 120.44 ? 7   THR D CG2   1 
ATOM   3278 N N     . ILE B 2 8   ? 137.898 123.351 112.673 1.00 83.38  ? 8   ILE D N     1 
ATOM   3279 C CA    . ILE B 2 8   ? 137.192 123.182 113.931 1.00 83.38  ? 8   ILE D CA    1 
ATOM   3280 C C     . ILE B 2 8   ? 135.819 122.601 113.650 1.00 83.38  ? 8   ILE D C     1 
ATOM   3281 O O     . ILE B 2 8   ? 135.081 123.126 112.813 1.00 83.38  ? 8   ILE D O     1 
ATOM   3282 C CB    . ILE B 2 8   ? 137.074 124.509 114.667 1.00 123.37 ? 8   ILE D CB    1 
ATOM   3283 C CG1   . ILE B 2 8   ? 138.453 125.106 114.874 1.00 123.37 ? 8   ILE D CG1   1 
ATOM   3284 C CG2   . ILE B 2 8   ? 136.408 124.265 116.004 1.00 123.37 ? 8   ILE D CG2   1 
ATOM   3285 C CD1   . ILE B 2 8   ? 138.470 126.532 115.367 1.00 123.37 ? 8   ILE D CD1   1 
ATOM   3286 N N     . HIS B 2 9   ? 135.477 121.520 114.315 1.00 84.46  ? 9   HIS D N     1 
ATOM   3287 C CA    . HIS B 2 9   ? 134.202 120.864 114.110 1.00 84.46  ? 9   HIS D CA    1 
ATOM   3288 C C     . HIS B 2 9   ? 133.321 121.138 115.304 1.00 84.46  ? 9   HIS D C     1 
ATOM   3289 O O     . HIS B 2 9   ? 133.686 120.780 116.415 1.00 84.46  ? 9   HIS D O     1 
ATOM   3290 C CB    . HIS B 2 9   ? 134.404 119.373 113.941 1.00 114.84 ? 9   HIS D CB    1 
ATOM   3291 C CG    . HIS B 2 9   ? 135.161 118.986 112.725 1.00 114.84 ? 9   HIS D CG    1 
ATOM   3292 N ND1   . HIS B 2 9   ? 134.532 118.630 111.576 1.00 114.84 ? 9   HIS D ND1   1 
ATOM   3293 C CD2   . HIS B 2 9   ? 136.477 118.842 112.488 1.00 114.84 ? 9   HIS D CD2   1 
ATOM   3294 C CE1   . HIS B 2 9   ? 135.421 118.317 110.667 1.00 114.84 ? 9   HIS D CE1   1 
ATOM   3295 N NE2   . HIS B 2 9   ? 136.616 118.427 111.198 1.00 114.84 ? 9   HIS D NE2   1 
ATOM   3296 N N     . VAL B 2 10  ? 132.184 121.796 115.117 1.00 82.81  ? 10  VAL D N     1 
ATOM   3297 C CA    . VAL B 2 10  ? 131.376 122.212 116.255 1.00 82.81  ? 10  VAL D CA    1 
ATOM   3298 C C     . VAL B 2 10  ? 129.971 121.668 116.197 1.00 82.81  ? 10  VAL D C     1 
ATOM   3299 O O     . VAL B 2 10  ? 129.243 121.919 115.244 1.00 82.81  ? 10  VAL D O     1 
ATOM   3300 C CB    . VAL B 2 10  ? 131.307 123.721 116.345 1.00 120.41 ? 10  VAL D CB    1 
ATOM   3301 C CG1   . VAL B 2 10  ? 130.565 124.116 117.550 1.00 120.41 ? 10  VAL D CG1   1 
ATOM   3302 C CG2   . VAL B 2 10  ? 132.686 124.285 116.358 1.00 120.41 ? 10  VAL D CG2   1 
ATOM   3303 N N     . GLY B 2 11  ? 129.571 120.990 117.232 1.00 83.15  ? 11  GLY D N     1 
ATOM   3304 C CA    . GLY B 2 11  ? 128.218 120.516 117.361 1.00 83.15  ? 11  GLY D CA    1 
ATOM   3305 C C     . GLY B 2 11  ? 127.978 119.223 116.622 1.00 83.15  ? 11  GLY D C     1 
ATOM   3306 O O     . GLY B 2 11  ? 128.911 118.593 116.119 1.00 83.15  ? 11  GLY D O     1 
ATOM   3307 N N     . GLU B 2 12  ? 126.714 118.842 116.487 1.00 85.29  ? 12  GLU D N     1 
ATOM   3308 C CA    . GLU B 2 12  ? 126.419 117.518 115.950 1.00 85.29  ? 12  GLU D CA    1 
ATOM   3309 C C     . GLU B 2 12  ? 126.840 117.329 114.513 1.00 85.29  ? 12  GLU D C     1 
ATOM   3310 O O     . GLU B 2 12  ? 127.418 116.291 114.193 1.00 85.29  ? 12  GLU D O     1 
ATOM   3311 C CB    . GLU B 2 12  ? 124.955 117.190 116.032 1.00 114.56 ? 12  GLU D CB    1 
ATOM   3312 C CG    . GLU B 2 12  ? 124.436 117.060 117.409 1.00 114.56 ? 12  GLU D CG    1 
ATOM   3313 C CD    . GLU B 2 12  ? 124.098 118.395 117.989 1.00 114.56 ? 12  GLU D CD    1 
ATOM   3314 O OE1   . GLU B 2 12  ? 124.308 119.402 117.306 1.00 114.56 ? 12  GLU D OE1   1 
ATOM   3315 O OE2   . GLU B 2 12  ? 123.620 118.445 119.116 1.00 114.56 ? 12  GLU D OE2   1 
ATOM   3316 N N     . LEU B 2 13  ? 126.536 118.256 113.608 1.00 86.72  ? 13  LEU D N     1 
ATOM   3317 C CA    . LEU B 2 13  ? 126.921 117.916 112.252 1.00 86.72  ? 13  LEU D CA    1 
ATOM   3318 C C     . LEU B 2 13  ? 128.397 118.125 112.045 1.00 86.72  ? 13  LEU D C     1 
ATOM   3319 O O     . LEU B 2 13  ? 129.029 117.351 111.338 1.00 86.72  ? 13  LEU D O     1 
ATOM   3320 C CB    . LEU B 2 13  ? 126.144 118.681 111.216 1.00 128.31 ? 13  LEU D CB    1 
ATOM   3321 C CG    . LEU B 2 13  ? 124.676 118.380 111.092 1.00 128.31 ? 13  LEU D CG    1 
ATOM   3322 C CD1   . LEU B 2 13  ? 124.083 119.295 110.087 1.00 128.31 ? 13  LEU D CD1   1 
ATOM   3323 C CD2   . LEU B 2 13  ? 124.438 116.994 110.670 1.00 128.31 ? 13  LEU D CD2   1 
ATOM   3324 N N     . GLY B 2 14  ? 128.991 119.099 112.688 1.00 87.65  ? 14  GLY D N     1 
ATOM   3325 C CA    . GLY B 2 14  ? 130.406 119.275 112.471 1.00 87.65  ? 14  GLY D CA    1 
ATOM   3326 C C     . GLY B 2 14  ? 131.150 118.017 112.854 1.00 87.65  ? 14  GLY D C     1 
ATOM   3327 O O     . GLY B 2 14  ? 132.082 117.576 112.152 1.00 87.65  ? 14  GLY D O     1 
ATOM   3328 N N     . ILE B 2 15  ? 130.685 117.368 113.918 1.00 86.19  ? 15  ILE D N     1 
ATOM   3329 C CA    . ILE B 2 15  ? 131.395 116.216 114.399 1.00 86.19  ? 15  ILE D CA    1 
ATOM   3330 C C     . ILE B 2 15  ? 130.948 114.955 113.713 1.00 86.19  ? 15  ILE D C     1 
ATOM   3331 O O     . ILE B 2 15  ? 131.783 114.096 113.433 1.00 86.19  ? 15  ILE D O     1 
ATOM   3332 C CB    . ILE B 2 15  ? 131.314 116.177 115.905 1.00 127.53 ? 15  ILE D CB    1 
ATOM   3333 C CG1   . ILE B 2 15  ? 132.130 117.379 116.348 1.00 127.53 ? 15  ILE D CG1   1 
ATOM   3334 C CG2   . ILE B 2 15  ? 131.919 114.916 116.440 1.00 127.53 ? 15  ILE D CG2   1 
ATOM   3335 C CD1   . ILE B 2 15  ? 132.007 117.744 117.733 1.00 127.53 ? 15  ILE D CD1   1 
ATOM   3336 N N     . GLN B 2 16  ? 129.674 114.808 113.368 1.00 87.37  ? 16  GLN D N     1 
ATOM   3337 C CA    . GLN B 2 16  ? 129.293 113.596 112.657 1.00 87.37  ? 16  GLN D CA    1 
ATOM   3338 C C     . GLN B 2 16  ? 129.884 113.580 111.261 1.00 87.37  ? 16  GLN D C     1 
ATOM   3339 O O     . GLN B 2 16  ? 130.154 112.504 110.725 1.00 87.37  ? 16  GLN D O     1 
ATOM   3340 C CB    . GLN B 2 16  ? 127.781 113.413 112.595 1.00 122.05 ? 16  GLN D CB    1 
ATOM   3341 C CG    . GLN B 2 16  ? 127.155 113.100 113.911 1.00 122.05 ? 16  GLN D CG    1 
ATOM   3342 C CD    . GLN B 2 16  ? 127.724 111.850 114.532 1.00 122.05 ? 16  GLN D CD    1 
ATOM   3343 O OE1   . GLN B 2 16  ? 127.613 110.749 113.985 1.00 122.05 ? 16  GLN D OE1   1 
ATOM   3344 N NE2   . GLN B 2 16  ? 128.371 112.020 115.676 1.00 122.05 ? 16  GLN D NE2   1 
ATOM   3345 N N     . ILE B 2 17  ? 130.113 114.744 110.664 1.00 86.70  ? 17  ILE D N     1 
ATOM   3346 C CA    . ILE B 2 17  ? 130.769 114.816 109.364 1.00 86.70  ? 17  ILE D CA    1 
ATOM   3347 C C     . ILE B 2 17  ? 132.225 114.464 109.473 1.00 86.70  ? 17  ILE D C     1 
ATOM   3348 O O     . ILE B 2 17  ? 132.757 113.792 108.597 1.00 86.70  ? 17  ILE D O     1 
ATOM   3349 C CB    . ILE B 2 17  ? 130.634 116.201 108.748 1.00 128.28 ? 17  ILE D CB    1 
ATOM   3350 C CG1   . ILE B 2 17  ? 129.214 116.430 108.376 1.00 128.28 ? 17  ILE D CG1   1 
ATOM   3351 C CG2   . ILE B 2 17  ? 131.517 116.332 107.531 1.00 128.28 ? 17  ILE D CG2   1 
ATOM   3352 C CD1   . ILE B 2 17  ? 128.924 117.829 108.047 1.00 128.28 ? 17  ILE D CD1   1 
ATOM   3353 N N     . ALA B 2 18  ? 132.906 114.949 110.511 1.00 84.75  ? 18  ALA D N     1 
ATOM   3354 C CA    . ALA B 2 18  ? 134.350 114.773 110.635 1.00 84.75  ? 18  ALA D CA    1 
ATOM   3355 C C     . ALA B 2 18  ? 134.898 113.436 110.154 1.00 84.75  ? 18  ALA D C     1 
ATOM   3356 O O     . ALA B 2 18  ? 135.798 113.453 109.318 1.00 84.75  ? 18  ALA D O     1 
ATOM   3357 C CB    . ALA B 2 18  ? 134.782 115.047 112.084 1.00 115.57 ? 18  ALA D CB    1 
ATOM   3358 N N     . PRO B 2 19  ? 134.406 112.285 110.555 1.00 82.66  ? 19  PRO D N     1 
ATOM   3359 C CA    . PRO B 2 19  ? 134.956 111.031 110.060 1.00 82.66  ? 19  PRO D CA    1 
ATOM   3360 C C     . PRO B 2 19  ? 134.863 110.843 108.575 1.00 82.66  ? 19  PRO D C     1 
ATOM   3361 O O     . PRO B 2 19  ? 135.696 110.148 108.007 1.00 82.66  ? 19  PRO D O     1 
ATOM   3362 C CB    . PRO B 2 19  ? 134.089 109.997 110.745 1.00 257.83 ? 19  PRO D CB    1 
ATOM   3363 C CG    . PRO B 2 19  ? 133.551 110.669 111.894 1.00 257.83 ? 19  PRO D CG    1 
ATOM   3364 C CD    . PRO B 2 19  ? 133.323 112.060 111.482 1.00 257.83 ? 19  PRO D CD    1 
ATOM   3365 N N     . ASN B 2 20  ? 133.896 111.430 107.895 1.00 83.66  ? 20  ASN D N     1 
ATOM   3366 C CA    . ASN B 2 20  ? 133.871 111.189 106.473 1.00 83.66  ? 20  ASN D CA    1 
ATOM   3367 C C     . ASN B 2 20  ? 134.773 112.164 105.785 1.00 83.66  ? 20  ASN D C     1 
ATOM   3368 O O     . ASN B 2 20  ? 135.472 111.830 104.829 1.00 83.66  ? 20  ASN D O     1 
ATOM   3369 C CB    . ASN B 2 20  ? 132.468 111.283 105.955 1.00 113.34 ? 20  ASN D CB    1 
ATOM   3370 C CG    . ASN B 2 20  ? 131.657 110.209 106.436 1.00 113.34 ? 20  ASN D CG    1 
ATOM   3371 O OD1   . ASN B 2 20  ? 131.763 109.081 105.975 1.00 113.34 ? 20  ASN D OD1   1 
ATOM   3372 N ND2   . ASN B 2 20  ? 130.826 110.500 107.378 1.00 113.34 ? 20  ASN D ND2   1 
ATOM   3373 N N     . PHE B 2 21  ? 134.816 113.354 106.323 1.00 84.32  ? 21  PHE D N     1 
ATOM   3374 C CA    . PHE B 2 21  ? 135.644 114.370 105.737 1.00 84.32  ? 21  PHE D CA    1 
ATOM   3375 C C     . PHE B 2 21  ? 137.084 113.977 105.848 1.00 84.32  ? 21  PHE D C     1 
ATOM   3376 O O     . PHE B 2 21  ? 137.827 113.992 104.860 1.00 84.32  ? 21  PHE D O     1 
ATOM   3377 C CB    . PHE B 2 21  ? 135.383 115.685 106.428 1.00 117.61 ? 21  PHE D CB    1 
ATOM   3378 C CG    . PHE B 2 21  ? 136.284 116.734 106.024 1.00 117.61 ? 21  PHE D CG    1 
ATOM   3379 C CD1   . PHE B 2 21  ? 136.228 117.245 104.798 1.00 117.61 ? 21  PHE D CD1   1 
ATOM   3380 C CD2   . PHE B 2 21  ? 137.157 117.226 106.882 1.00 117.61 ? 21  PHE D CD2   1 
ATOM   3381 C CE1   . PHE B 2 21  ? 137.058 118.233 104.436 1.00 117.61 ? 21  PHE D CE1   1 
ATOM   3382 C CE2   . PHE B 2 21  ? 137.986 118.213 106.523 1.00 117.61 ? 21  PHE D CE2   1 
ATOM   3383 C CZ    . PHE B 2 21  ? 137.933 118.707 105.300 1.00 117.61 ? 21  PHE D CZ    1 
ATOM   3384 N N     . TRP B 2 22  ? 137.487 113.564 107.023 1.00 83.40  ? 22  TRP D N     1 
ATOM   3385 C CA    . TRP B 2 22  ? 138.875 113.242 107.215 1.00 83.40  ? 22  TRP D CA    1 
ATOM   3386 C C     . TRP B 2 22  ? 139.238 111.932 106.574 1.00 83.40  ? 22  TRP D C     1 
ATOM   3387 O O     . TRP B 2 22  ? 140.357 111.799 106.095 1.00 83.40  ? 22  TRP D O     1 
ATOM   3388 C CB    . TRP B 2 22  ? 139.213 113.267 108.683 1.00 115.42 ? 22  TRP D CB    1 
ATOM   3389 C CG    . TRP B 2 22  ? 139.294 114.633 109.109 1.00 115.42 ? 22  TRP D CG    1 
ATOM   3390 C CD1   . TRP B 2 22  ? 138.363 115.324 109.715 1.00 115.42 ? 22  TRP D CD1   1 
ATOM   3391 C CD2   . TRP B 2 22  ? 140.366 115.501 108.909 1.00 115.42 ? 22  TRP D CD2   1 
ATOM   3392 N NE1   . TRP B 2 22  ? 138.762 116.585 109.904 1.00 115.42 ? 22  TRP D NE1   1 
ATOM   3393 C CE2   . TRP B 2 22  ? 140.003 116.710 109.380 1.00 115.42 ? 22  TRP D CE2   1 
ATOM   3394 C CE3   . TRP B 2 22  ? 141.588 115.370 108.328 1.00 115.42 ? 22  TRP D CE3   1 
ATOM   3395 C CZ2   . TRP B 2 22  ? 140.793 117.768 109.316 1.00 115.42 ? 22  TRP D CZ2   1 
ATOM   3396 C CZ3   . TRP B 2 22  ? 142.390 116.437 108.280 1.00 115.42 ? 22  TRP D CZ3   1 
ATOM   3397 C CH2   . TRP B 2 22  ? 141.998 117.615 108.774 1.00 115.42 ? 22  TRP D CH2   1 
ATOM   3398 N N     . LYS B 2 23  ? 138.329 110.981 106.490 1.00 83.98  ? 23  LYS D N     1 
ATOM   3399 C CA    . LYS B 2 23  ? 138.692 109.787 105.763 1.00 83.98  ? 23  LYS D CA    1 
ATOM   3400 C C     . LYS B 2 23  ? 138.932 110.108 104.306 1.00 83.98  ? 23  LYS D C     1 
ATOM   3401 O O     . LYS B 2 23  ? 139.881 109.593 103.705 1.00 83.98  ? 23  LYS D O     1 
ATOM   3402 C CB    . LYS B 2 23  ? 137.618 108.723 105.932 1.00 125.86 ? 23  LYS D CB    1 
ATOM   3403 C CG    . LYS B 2 23  ? 137.584 108.109 107.327 1.00 125.86 ? 23  LYS D CG    1 
ATOM   3404 C CD    . LYS B 2 23  ? 136.435 107.108 107.534 1.00 125.86 ? 23  LYS D CD    1 
ATOM   3405 C CE    . LYS B 2 23  ? 136.423 106.605 108.963 1.00 125.86 ? 23  LYS D CE    1 
ATOM   3406 N NZ    . LYS B 2 23  ? 135.339 105.617 109.248 1.00 125.86 ? 23  LYS D NZ    1 
ATOM   3407 N N     . TYR B 2 24  ? 138.099 110.958 103.710 1.00 83.62  ? 24  TYR D N     1 
ATOM   3408 C CA    . TYR B 2 24  ? 138.323 111.279 102.316 1.00 83.62  ? 24  TYR D CA    1 
ATOM   3409 C C     . TYR B 2 24  ? 139.651 111.966 102.130 1.00 83.62  ? 24  TYR D C     1 
ATOM   3410 O O     . TYR B 2 24  ? 140.366 111.672 101.167 1.00 83.62  ? 24  TYR D O     1 
ATOM   3411 C CB    . TYR B 2 24  ? 137.226 112.149 101.749 1.00 115.74 ? 24  TYR D CB    1 
ATOM   3412 C CG    . TYR B 2 24  ? 135.915 111.510 101.505 1.00 115.74 ? 24  TYR D CG    1 
ATOM   3413 C CD1   . TYR B 2 24  ? 135.815 110.333 100.883 1.00 115.74 ? 24  TYR D CD1   1 
ATOM   3414 C CD2   . TYR B 2 24  ? 134.767 112.120 101.923 1.00 115.74 ? 24  TYR D CD2   1 
ATOM   3415 C CE1   . TYR B 2 24  ? 134.618 109.770 100.664 1.00 115.74 ? 24  TYR D CE1   1 
ATOM   3416 C CE2   . TYR B 2 24  ? 133.561 111.554 101.716 1.00 115.74 ? 24  TYR D CE2   1 
ATOM   3417 C CZ    . TYR B 2 24  ? 133.495 110.378 101.081 1.00 115.74 ? 24  TYR D CZ    1 
ATOM   3418 O OH    . TYR B 2 24  ? 132.277 109.784 100.865 1.00 115.74 ? 24  TYR D OH    1 
ATOM   3419 N N     . LEU B 2 25  ? 140.002 112.898 103.009 1.00 84.09  ? 25  LEU D N     1 
ATOM   3420 C CA    . LEU B 2 25  ? 141.281 113.567 102.832 1.00 84.09  ? 25  LEU D CA    1 
ATOM   3421 C C     . LEU B 2 25  ? 142.383 112.578 102.966 1.00 84.09  ? 25  LEU D C     1 
ATOM   3422 O O     . LEU B 2 25  ? 143.399 112.676 102.281 1.00 84.09  ? 25  LEU D O     1 
ATOM   3423 C CB    . LEU B 2 25  ? 141.520 114.651 103.859 1.00 124.42 ? 25  LEU D CB    1 
ATOM   3424 C CG    . LEU B 2 25  ? 140.604 115.833 103.835 1.00 124.42 ? 25  LEU D CG    1 
ATOM   3425 C CD1   . LEU B 2 25  ? 140.957 116.701 104.984 1.00 124.42 ? 25  LEU D CD1   1 
ATOM   3426 C CD2   . LEU B 2 25  ? 140.745 116.564 102.587 1.00 124.42 ? 25  LEU D CD2   1 
ATOM   3427 N N     . CYS B 2 26  ? 142.230 111.642 103.882 1.00 87.18  ? 26  CYS D N     1 
ATOM   3428 C CA    . CYS B 2 26  ? 143.290 110.686 104.073 1.00 87.18  ? 26  CYS D CA    1 
ATOM   3429 C C     . CYS B 2 26  ? 143.509 109.911 102.809 1.00 87.18  ? 26  CYS D C     1 
ATOM   3430 O O     . CYS B 2 26  ? 144.650 109.697 102.398 1.00 87.18  ? 26  CYS D O     1 
ATOM   3431 C CB    . CYS B 2 26  ? 142.975 109.758 105.230 1.00 117.42 ? 26  CYS D CB    1 
ATOM   3432 S SG    . CYS B 2 26  ? 143.054 110.524 106.855 1.00 117.42 ? 26  CYS D SG    1 
ATOM   3433 N N     . ASP B 2 27  ? 142.448 109.499 102.148 1.00 88.41  ? 27  ASP D N     1 
ATOM   3434 C CA    . ASP B 2 27  ? 142.692 108.730 100.946 1.00 88.41  ? 27  ASP D CA    1 
ATOM   3435 C C     . ASP B 2 27  ? 143.273 109.586 99.860  1.00 88.41  ? 27  ASP D C     1 
ATOM   3436 O O     . ASP B 2 27  ? 144.176 109.160 99.147  1.00 88.41  ? 27  ASP D O     1 
ATOM   3437 C CB    . ASP B 2 27  ? 141.429 108.049 100.475 1.00 113.67 ? 27  ASP D CB    1 
ATOM   3438 C CG    . ASP B 2 27  ? 141.088 106.839 101.323 1.00 113.67 ? 27  ASP D CG    1 
ATOM   3439 O OD1   . ASP B 2 27  ? 141.978 106.311 101.997 1.00 113.67 ? 27  ASP D OD1   1 
ATOM   3440 O OD2   . ASP B 2 27  ? 139.934 106.415 101.325 1.00 113.67 ? 27  ASP D OD2   1 
ATOM   3441 N N     . GLU B 2 28  ? 142.830 110.822 99.760  1.00 89.80  ? 28  GLU D N     1 
ATOM   3442 C CA    . GLU B 2 28  ? 143.301 111.671 98.682  1.00 89.80  ? 28  GLU D CA    1 
ATOM   3443 C C     . GLU B 2 28  ? 144.803 111.812 98.694  1.00 89.80  ? 28  GLU D C     1 
ATOM   3444 O O     . GLU B 2 28  ? 145.420 111.845 97.630  1.00 89.80  ? 28  GLU D O     1 
ATOM   3445 C CB    . GLU B 2 28  ? 142.660 113.046 98.761  1.00 120.61 ? 28  GLU D CB    1 
ATOM   3446 C CG    . GLU B 2 28  ? 142.973 113.907 97.560  1.00 120.61 ? 28  GLU D CG    1 
ATOM   3447 C CD    . GLU B 2 28  ? 142.349 115.244 97.629  1.00 120.61 ? 28  GLU D CD    1 
ATOM   3448 O OE1   . GLU B 2 28  ? 142.410 115.856 98.684  1.00 120.61 ? 28  GLU D OE1   1 
ATOM   3449 O OE2   . GLU B 2 28  ? 141.800 115.696 96.631  1.00 120.61 ? 28  GLU D OE2   1 
ATOM   3450 N N     . HIS B 2 29  ? 145.405 111.910 99.877  1.00 87.56  ? 29  HIS D N     1 
ATOM   3451 C CA    . HIS B 2 29  ? 146.825 112.141 100.067 1.00 87.56  ? 29  HIS D CA    1 
ATOM   3452 C C     . HIS B 2 29  ? 147.645 110.898 100.330 1.00 87.56  ? 29  HIS D C     1 
ATOM   3453 O O     . HIS B 2 29  ? 148.836 111.034 100.620 1.00 87.56  ? 29  HIS D O     1 
ATOM   3454 C CB    . HIS B 2 29  ? 147.078 113.002 101.259 1.00 119.06 ? 29  HIS D CB    1 
ATOM   3455 C CG    . HIS B 2 29  ? 146.602 114.351 101.151 1.00 119.06 ? 29  HIS D CG    1 
ATOM   3456 N ND1   . HIS B 2 29  ? 147.150 115.255 100.301 1.00 119.06 ? 29  HIS D ND1   1 
ATOM   3457 C CD2   . HIS B 2 29  ? 145.636 114.980 101.815 1.00 119.06 ? 29  HIS D CD2   1 
ATOM   3458 C CE1   . HIS B 2 29  ? 146.531 116.401 100.442 1.00 119.06 ? 29  HIS D CE1   1 
ATOM   3459 N NE2   . HIS B 2 29  ? 145.610 116.258 101.363 1.00 119.06 ? 29  HIS D NE2   1 
ATOM   3460 N N     . ASN B 2 30  ? 147.055 109.710 100.287 1.00 92.47  ? 30  ASN D N     1 
ATOM   3461 C CA    . ASN B 2 30  ? 147.695 108.432 100.675 1.00 92.47  ? 30  ASN D CA    1 
ATOM   3462 C C     . ASN B 2 30  ? 148.107 108.338 102.147 1.00 92.47  ? 30  ASN D C     1 
ATOM   3463 O O     . ASN B 2 30  ? 149.193 107.891 102.492 1.00 92.47  ? 30  ASN D O     1 
ATOM   3464 C CB    . ASN B 2 30  ? 148.875 108.102 99.796  1.00 125.27 ? 30  ASN D CB    1 
ATOM   3465 C CG    . ASN B 2 30  ? 148.481 107.772 98.423  1.00 125.27 ? 30  ASN D CG    1 
ATOM   3466 O OD1   . ASN B 2 30  ? 147.393 107.278 98.167  1.00 125.27 ? 30  ASN D OD1   1 
ATOM   3467 N ND2   . ASN B 2 30  ? 149.386 108.007 97.506  1.00 125.27 ? 30  ASN D ND2   1 
ATOM   3468 N N     . ILE B 2 31  ? 147.195 108.701 103.017 1.00 88.48  ? 31  ILE D N     1 
ATOM   3469 C CA    . ILE B 2 31  ? 147.349 108.549 104.433 1.00 88.48  ? 31  ILE D CA    1 
ATOM   3470 C C     . ILE B 2 31  ? 146.462 107.393 104.799 1.00 88.48  ? 31  ILE D C     1 
ATOM   3471 O O     . ILE B 2 31  ? 145.273 107.413 104.512 1.00 88.48  ? 31  ILE D O     1 
ATOM   3472 C CB    . ILE B 2 31  ? 146.902 109.808 105.160 1.00 130.92 ? 31  ILE D CB    1 
ATOM   3473 C CG1   . ILE B 2 31  ? 147.683 111.003 104.642 1.00 130.92 ? 31  ILE D CG1   1 
ATOM   3474 C CG2   . ILE B 2 31  ? 147.055 109.636 106.645 1.00 130.92 ? 31  ILE D CG2   1 
ATOM   3475 C CD1   . ILE B 2 31  ? 147.054 112.322 105.004 1.00 130.92 ? 31  ILE D CD1   1 
ATOM   3476 N N     . ASP B 2 32  ? 146.982 106.393 105.460 1.00 91.08  ? 32  ASP D N     1 
ATOM   3477 C CA    . ASP B 2 32  ? 146.169 105.201 105.691 1.00 91.08  ? 32  ASP D CA    1 
ATOM   3478 C C     . ASP B 2 32  ? 145.318 105.277 106.958 1.00 91.08  ? 32  ASP D C     1 
ATOM   3479 O O     . ASP B 2 32  ? 145.548 104.555 107.917 1.00 91.08  ? 32  ASP D O     1 
ATOM   3480 C CB    . ASP B 2 32  ? 147.063 103.975 105.760 1.00 117.10 ? 32  ASP D CB    1 
ATOM   3481 C CG    . ASP B 2 32  ? 146.275 102.688 105.666 1.00 117.10 ? 32  ASP D CG    1 
ATOM   3482 O OD1   . ASP B 2 32  ? 145.130 102.748 105.209 1.00 117.10 ? 32  ASP D OD1   1 
ATOM   3483 O OD2   . ASP B 2 32  ? 146.793 101.626 106.022 1.00 117.10 ? 32  ASP D OD2   1 
ATOM   3484 N N     . TYR B 2 33  ? 144.358 106.182 106.974 1.00 86.19  ? 33  TYR D N     1 
ATOM   3485 C CA    . TYR B 2 33  ? 143.326 106.349 107.998 1.00 86.19  ? 33  TYR D CA    1 
ATOM   3486 C C     . TYR B 2 33  ? 143.747 106.648 109.423 1.00 86.19  ? 33  TYR D C     1 
ATOM   3487 O O     . TYR B 2 33  ? 143.215 107.587 110.011 1.00 86.19  ? 33  TYR D O     1 
ATOM   3488 C CB    . TYR B 2 33  ? 142.453 105.123 108.030 1.00 119.30 ? 33  TYR D CB    1 
ATOM   3489 C CG    . TYR B 2 33  ? 141.564 105.142 106.868 1.00 119.30 ? 33  TYR D CG    1 
ATOM   3490 C CD1   . TYR B 2 33  ? 142.002 104.748 105.634 1.00 119.30 ? 33  TYR D CD1   1 
ATOM   3491 C CD2   . TYR B 2 33  ? 140.302 105.555 106.977 1.00 119.30 ? 33  TYR D CD2   1 
ATOM   3492 C CE1   . TYR B 2 33  ? 141.164 104.809 104.551 1.00 119.30 ? 33  TYR D CE1   1 
ATOM   3493 C CE2   . TYR B 2 33  ? 139.479 105.598 105.907 1.00 119.30 ? 33  TYR D CE2   1 
ATOM   3494 C CZ    . TYR B 2 33  ? 139.901 105.258 104.714 1.00 119.30 ? 33  TYR D CZ    1 
ATOM   3495 O OH    . TYR B 2 33  ? 139.042 105.314 103.665 1.00 119.30 ? 33  TYR D OH    1 
ATOM   3496 N N     . LYS B 2 34  ? 144.778 106.021 109.938 1.00 91.72  ? 34  LYS D N     1 
ATOM   3497 C CA    . LYS B 2 34  ? 145.261 106.282 111.286 1.00 91.72  ? 34  LYS D CA    1 
ATOM   3498 C C     . LYS B 2 34  ? 146.455 107.187 111.272 1.00 91.72  ? 34  LYS D C     1 
ATOM   3499 O O     . LYS B 2 34  ? 147.146 107.308 112.275 1.00 91.72  ? 34  LYS D O     1 
ATOM   3500 C CB    . LYS B 2 34  ? 145.630 104.995 112.011 1.00 137.46 ? 34  LYS D CB    1 
ATOM   3501 C CG    . LYS B 2 34  ? 144.477 104.113 112.402 1.00 137.46 ? 34  LYS D CG    1 
ATOM   3502 C CD    . LYS B 2 34  ? 144.972 102.907 113.168 1.00 137.46 ? 34  LYS D CD    1 
ATOM   3503 C CE    . LYS B 2 34  ? 143.822 102.060 113.664 1.00 137.46 ? 34  LYS D CE    1 
ATOM   3504 N NZ    . LYS B 2 34  ? 144.304 100.836 114.368 1.00 137.46 ? 34  LYS D NZ    1 
ATOM   3505 N N     . GLY B 2 35  ? 146.736 107.789 110.149 1.00 93.97  ? 35  GLY D N     1 
ATOM   3506 C CA    . GLY B 2 35  ? 147.864 108.670 110.008 1.00 93.97  ? 35  GLY D CA    1 
ATOM   3507 C C     . GLY B 2 35  ? 149.082 108.018 109.394 1.00 93.97  ? 35  GLY D C     1 
ATOM   3508 O O     . GLY B 2 35  ? 150.045 108.709 109.064 1.00 93.97  ? 35  GLY D O     1 
ATOM   3509 N N     . GLN B 2 36  ? 149.055 106.715 109.213 1.00 94.13  ? 36  GLN D N     1 
ATOM   3510 C CA    . GLN B 2 36  ? 150.195 106.001 108.669 1.00 94.13  ? 36  GLN D CA    1 
ATOM   3511 C C     . GLN B 2 36  ? 150.440 106.332 107.213 1.00 94.13  ? 36  GLN D C     1 
ATOM   3512 O O     . GLN B 2 36  ? 149.534 106.283 106.391 1.00 94.13  ? 36  GLN D O     1 
ATOM   3513 C CB    . GLN B 2 36  ? 149.965 104.516 108.832 1.00 131.49 ? 36  GLN D CB    1 
ATOM   3514 C CG    . GLN B 2 36  ? 150.970 103.630 108.130 1.00 131.49 ? 36  GLN D CG    1 
ATOM   3515 C CD    . GLN B 2 36  ? 152.366 103.712 108.710 1.00 131.49 ? 36  GLN D CD    1 
ATOM   3516 O OE1   . GLN B 2 36  ? 152.560 103.566 109.919 1.00 131.49 ? 36  GLN D OE1   1 
ATOM   3517 N NE2   . GLN B 2 36  ? 153.352 103.942 107.845 1.00 131.49 ? 36  GLN D NE2   1 
ATOM   3518 N N     . GLU B 2 37  ? 151.672 106.635 106.873 1.00 98.07  ? 37  GLU D N     1 
ATOM   3519 C CA    . GLU B 2 37  ? 152.004 106.932 105.490 1.00 98.07  ? 37  GLU D CA    1 
ATOM   3520 C C     . GLU B 2 37  ? 152.026 105.676 104.649 1.00 98.07  ? 37  GLU D C     1 
ATOM   3521 O O     . GLU B 2 37  ? 152.599 104.669 105.049 1.00 98.07  ? 37  GLU D O     1 
ATOM   3522 C CB    . GLU B 2 37  ? 153.363 107.599 105.419 1.00 131.72 ? 37  GLU D CB    1 
ATOM   3523 C CG    . GLU B 2 37  ? 153.814 107.926 104.052 1.00 131.72 ? 37  GLU D CG    1 
ATOM   3524 C CD    . GLU B 2 37  ? 155.096 108.664 104.061 1.00 131.72 ? 37  GLU D CD    1 
ATOM   3525 O OE1   . GLU B 2 37  ? 155.690 108.776 105.125 1.00 131.72 ? 37  GLU D OE1   1 
ATOM   3526 O OE2   . GLU B 2 37  ? 155.519 109.143 103.014 1.00 131.72 ? 37  GLU D OE2   1 
ATOM   3527 N N     . LYS B 2 38  ? 151.429 105.727 103.472 1.00 93.31  ? 38  LYS D N     1 
ATOM   3528 C CA    . LYS B 2 38  ? 151.510 104.608 102.555 1.00 93.31  ? 38  LYS D CA    1 
ATOM   3529 C C     . LYS B 2 38  ? 151.904 105.138 101.201 1.00 93.31  ? 38  LYS D C     1 
ATOM   3530 O O     . LYS B 2 38  ? 151.525 106.236 100.835 1.00 93.31  ? 38  LYS D O     1 
ATOM   3531 C CB    . LYS B 2 38  ? 150.194 103.844 102.450 1.00 139.84 ? 38  LYS D CB    1 
ATOM   3532 C CG    . LYS B 2 38  ? 149.043 104.607 101.878 1.00 139.84 ? 38  LYS D CG    1 
ATOM   3533 C CD    . LYS B 2 38  ? 147.799 103.771 101.806 1.00 139.84 ? 38  LYS D CD    1 
ATOM   3534 C CE    . LYS B 2 38  ? 146.645 104.531 101.226 1.00 139.84 ? 38  LYS D CE    1 
ATOM   3535 N NZ    . LYS B 2 38  ? 145.403 103.717 101.138 1.00 139.84 ? 38  LYS D NZ    1 
ATOM   3536 N N     . GLY B 2 39  ? 152.638 104.355 100.447 1.00 94.22  ? 39  GLY D N     1 
ATOM   3537 C CA    . GLY B 2 39  ? 152.987 104.819 99.126  1.00 94.22  ? 39  GLY D CA    1 
ATOM   3538 C C     . GLY B 2 39  ? 153.765 106.096 99.246  1.00 94.22  ? 39  GLY D C     1 
ATOM   3539 O O     . GLY B 2 39  ? 154.731 106.177 99.998  1.00 94.22  ? 39  GLY D O     1 
ATOM   3540 N N     . LYS B 2 40  ? 153.348 107.103 98.509  1.00 94.32  ? 40  LYS D N     1 
ATOM   3541 C CA    . LYS B 2 40  ? 153.999 108.389 98.511  1.00 94.32  ? 40  LYS D CA    1 
ATOM   3542 C C     . LYS B 2 40  ? 152.980 109.462 98.804  1.00 94.32  ? 40  LYS D C     1 
ATOM   3543 O O     . LYS B 2 40  ? 151.838 109.390 98.362  1.00 94.32  ? 40  LYS D O     1 
ATOM   3544 C CB    . LYS B 2 40  ? 154.640 108.693 97.179  1.00 141.35 ? 40  LYS D CB    1 
ATOM   3545 C CG    . LYS B 2 40  ? 155.676 107.675 96.699  1.00 141.35 ? 40  LYS D CG    1 
ATOM   3546 C CD    . LYS B 2 40  ? 156.955 107.702 97.533  1.00 141.35 ? 40  LYS D CD    1 
ATOM   3547 C CE    . LYS B 2 40  ? 158.008 106.750 96.975  1.00 141.35 ? 40  LYS D CE    1 
ATOM   3548 N NZ    . LYS B 2 40  ? 159.243 106.722 97.814  1.00 141.35 ? 40  LYS D NZ    1 
ATOM   3549 N N     . ILE B 2 41  ? 153.396 110.479 99.539  1.00 91.21  ? 41  ILE D N     1 
ATOM   3550 C CA    . ILE B 2 41  ? 152.474 111.551 99.838  1.00 91.21  ? 41  ILE D CA    1 
ATOM   3551 C C     . ILE B 2 41  ? 152.272 112.380 98.605  1.00 91.21  ? 41  ILE D C     1 
ATOM   3552 O O     . ILE B 2 41  ? 153.235 112.744 97.925  1.00 91.21  ? 41  ILE D O     1 
ATOM   3553 C CB    . ILE B 2 41  ? 152.989 112.416 100.973 1.00 134.96 ? 41  ILE D CB    1 
ATOM   3554 C CG1   . ILE B 2 41  ? 153.063 111.597 102.272 1.00 134.96 ? 41  ILE D CG1   1 
ATOM   3555 C CG2   . ILE B 2 41  ? 152.101 113.613 101.122 1.00 134.96 ? 41  ILE D CG2   1 
ATOM   3556 C CD1   . ILE B 2 41  ? 151.730 110.957 102.782 1.00 134.96 ? 41  ILE D CD1   1 
ATOM   3557 N N     . ARG B 2 42  ? 151.031 112.688 98.313  1.00 89.94  ? 42  ARG D N     1 
ATOM   3558 C CA    . ARG B 2 42  ? 150.712 113.506 97.172  1.00 89.94  ? 42  ARG D CA    1 
ATOM   3559 C C     . ARG B 2 42  ? 149.797 114.631 97.595  1.00 89.94  ? 42  ARG D C     1 
ATOM   3560 O O     . ARG B 2 42  ? 148.928 114.429 98.438  1.00 89.94  ? 42  ARG D O     1 
ATOM   3561 C CB    . ARG B 2 42  ? 150.081 112.674 96.109  1.00 132.05 ? 42  ARG D CB    1 
ATOM   3562 C CG    . ARG B 2 42  ? 148.863 111.958 96.519  1.00 132.05 ? 42  ARG D CG    1 
ATOM   3563 C CD    . ARG B 2 42  ? 148.446 110.992 95.484  1.00 132.05 ? 42  ARG D CD    1 
ATOM   3564 N NE    . ARG B 2 42  ? 147.278 110.237 95.897  1.00 132.05 ? 42  ARG D NE    1 
ATOM   3565 C CZ    . ARG B 2 42  ? 146.875 109.103 95.338  1.00 132.05 ? 42  ARG D CZ    1 
ATOM   3566 N NH1   . ARG B 2 42  ? 147.532 108.562 94.334  1.00 132.05 ? 42  ARG D NH1   1 
ATOM   3567 N NH2   . ARG B 2 42  ? 145.792 108.491 95.809  1.00 132.05 ? 42  ARG D NH2   1 
ATOM   3568 N N     . GLY B 2 43  ? 150.006 115.813 97.027  1.00 88.27  ? 43  GLY D N     1 
ATOM   3569 C CA    . GLY B 2 43  ? 149.272 117.007 97.381  1.00 88.27  ? 43  GLY D CA    1 
ATOM   3570 C C     . GLY B 2 43  ? 149.989 117.745 98.478  1.00 88.27  ? 43  GLY D C     1 
ATOM   3571 O O     . GLY B 2 43  ? 150.962 117.264 99.043  1.00 88.27  ? 43  GLY D O     1 
ATOM   3572 N N     . VAL B 2 44  ? 149.522 118.928 98.829  1.00 86.09  ? 44  VAL D N     1 
ATOM   3573 C CA    . VAL B 2 44  ? 150.226 119.683 99.851  1.00 86.09  ? 44  VAL D CA    1 
ATOM   3574 C C     . VAL B 2 44  ? 149.678 119.243 101.188 1.00 86.09  ? 44  VAL D C     1 
ATOM   3575 O O     . VAL B 2 44  ? 148.847 119.904 101.789 1.00 86.09  ? 44  VAL D O     1 
ATOM   3576 C CB    . VAL B 2 44  ? 150.073 121.166 99.680  1.00 125.18 ? 44  VAL D CB    1 
ATOM   3577 C CG1   . VAL B 2 44  ? 150.907 121.888 100.733 1.00 125.18 ? 44  VAL D CG1   1 
ATOM   3578 C CG2   . VAL B 2 44  ? 150.462 121.548 98.293  1.00 125.18 ? 44  VAL D CG2   1 
ATOM   3579 N N     . ILE B 2 45  ? 150.247 118.170 101.699 1.00 85.63  ? 45  ILE D N     1 
ATOM   3580 C CA    . ILE B 2 45  ? 149.711 117.529 102.867 1.00 85.63  ? 45  ILE D CA    1 
ATOM   3581 C C     . ILE B 2 45  ? 149.748 118.423 104.074 1.00 85.63  ? 45  ILE D C     1 
ATOM   3582 O O     . ILE B 2 45  ? 148.836 118.371 104.906 1.00 85.63  ? 45  ILE D O     1 
ATOM   3583 C CB    . ILE B 2 45  ? 150.465 116.239 103.114 1.00 126.70 ? 45  ILE D CB    1 
ATOM   3584 C CG1   . ILE B 2 45  ? 149.748 115.480 104.187 1.00 126.70 ? 45  ILE D CG1   1 
ATOM   3585 C CG2   . ILE B 2 45  ? 151.876 116.524 103.501 1.00 126.70 ? 45  ILE D CG2   1 
ATOM   3586 C CD1   . ILE B 2 45  ? 150.153 114.077 104.282 1.00 126.70 ? 45  ILE D CD1   1 
ATOM   3587 N N     . ASP B 2 46  ? 150.753 119.288 104.165 1.00 85.65  ? 46  ASP D N     1 
ATOM   3588 C CA    . ASP B 2 46  ? 150.928 120.149 105.319 1.00 85.65  ? 46  ASP D CA    1 
ATOM   3589 C C     . ASP B 2 46  ? 149.734 121.034 105.548 1.00 85.65  ? 46  ASP D C     1 
ATOM   3590 O O     . ASP B 2 46  ? 149.490 121.468 106.676 1.00 85.65  ? 46  ASP D O     1 
ATOM   3591 C CB    . ASP B 2 46  ? 152.131 121.043 105.153 1.00 110.12 ? 46  ASP D CB    1 
ATOM   3592 C CG    . ASP B 2 46  ? 153.431 120.342 105.243 1.00 110.12 ? 46  ASP D CG    1 
ATOM   3593 O OD1   . ASP B 2 46  ? 153.529 119.254 105.782 1.00 110.12 ? 46  ASP D OD1   1 
ATOM   3594 O OD2   . ASP B 2 46  ? 154.408 120.896 104.760 1.00 110.12 ? 46  ASP D OD2   1 
ATOM   3595 N N     . ASN B 2 47  ? 148.979 121.325 104.515 1.00 86.77  ? 47  ASN D N     1 
ATOM   3596 C CA    . ASN B 2 47  ? 147.913 122.265 104.703 1.00 86.77  ? 47  ASN D CA    1 
ATOM   3597 C C     . ASN B 2 47  ? 146.836 121.745 105.628 1.00 86.77  ? 47  ASN D C     1 
ATOM   3598 O O     . ASN B 2 47  ? 146.210 122.540 106.332 1.00 86.77  ? 47  ASN D O     1 
ATOM   3599 C CB    . ASN B 2 47  ? 147.363 122.661 103.367 1.00 117.55 ? 47  ASN D CB    1 
ATOM   3600 C CG    . ASN B 2 47  ? 148.326 123.507 102.633 1.00 117.55 ? 47  ASN D CG    1 
ATOM   3601 O OD1   . ASN B 2 47  ? 149.317 123.938 103.202 1.00 117.55 ? 47  ASN D OD1   1 
ATOM   3602 N ND2   . ASN B 2 47  ? 148.063 123.778 101.380 1.00 117.55 ? 47  ASN D ND2   1 
ATOM   3603 N N     . PHE B 2 48  ? 146.624 120.449 105.693 1.00 82.62  ? 48  PHE D N     1 
ATOM   3604 C CA    . PHE B 2 48  ? 145.624 119.923 106.600 1.00 82.62  ? 48  PHE D CA    1 
ATOM   3605 C C     . PHE B 2 48  ? 146.120 118.939 107.635 1.00 82.62  ? 48  PHE D C     1 
ATOM   3606 O O     . PHE B 2 48  ? 145.403 118.707 108.614 1.00 82.62  ? 48  PHE D O     1 
ATOM   3607 C CB    . PHE B 2 48  ? 144.472 119.365 105.791 1.00 115.24 ? 48  PHE D CB    1 
ATOM   3608 C CG    . PHE B 2 48  ? 143.730 120.451 105.194 1.00 115.24 ? 48  PHE D CG    1 
ATOM   3609 C CD1   . PHE B 2 48  ? 144.104 120.983 104.031 1.00 115.24 ? 48  PHE D CD1   1 
ATOM   3610 C CD2   . PHE B 2 48  ? 142.705 120.979 105.843 1.00 115.24 ? 48  PHE D CD2   1 
ATOM   3611 C CE1   . PHE B 2 48  ? 143.454 122.041 103.531 1.00 115.24 ? 48  PHE D CE1   1 
ATOM   3612 C CE2   . PHE B 2 48  ? 142.049 122.019 105.365 1.00 115.24 ? 48  PHE D CE2   1 
ATOM   3613 C CZ    . PHE B 2 48  ? 142.432 122.566 104.208 1.00 115.24 ? 48  PHE D CZ    1 
ATOM   3614 N N     . PHE B 2 49  ? 147.315 118.411 107.510 1.00 85.88  ? 49  PHE D N     1 
ATOM   3615 C CA    . PHE B 2 49  ? 147.806 117.457 108.472 1.00 85.88  ? 49  PHE D CA    1 
ATOM   3616 C C     . PHE B 2 49  ? 149.120 117.889 109.090 1.00 85.88  ? 49  PHE D C     1 
ATOM   3617 O O     . PHE B 2 49  ? 150.015 118.368 108.410 1.00 85.88  ? 49  PHE D O     1 
ATOM   3618 C CB    . PHE B 2 49  ? 147.995 116.133 107.834 1.00 119.79 ? 49  PHE D CB    1 
ATOM   3619 C CG    . PHE B 2 49  ? 146.760 115.501 107.360 1.00 119.79 ? 49  PHE D CG    1 
ATOM   3620 C CD1   . PHE B 2 49  ? 146.234 115.813 106.175 1.00 119.79 ? 49  PHE D CD1   1 
ATOM   3621 C CD2   . PHE B 2 49  ? 146.157 114.539 108.097 1.00 119.79 ? 49  PHE D CD2   1 
ATOM   3622 C CE1   . PHE B 2 49  ? 145.127 115.219 105.742 1.00 119.79 ? 49  PHE D CE1   1 
ATOM   3623 C CE2   . PHE B 2 49  ? 145.048 113.942 107.659 1.00 119.79 ? 49  PHE D CE2   1 
ATOM   3624 C CZ    . PHE B 2 49  ? 144.533 114.283 106.479 1.00 119.79 ? 49  PHE D CZ    1 
ATOM   3625 N N     . GLU B 2 50  ? 149.265 117.659 110.358 1.00 87.61  ? 50  GLU D N     1 
ATOM   3626 C CA    . GLU B 2 50  ? 150.481 118.009 111.048 1.00 87.61  ? 50  GLU D CA    1 
ATOM   3627 C C     . GLU B 2 50  ? 151.408 116.821 111.071 1.00 87.61  ? 50  GLU D C     1 
ATOM   3628 O O     . GLU B 2 50  ? 150.979 115.673 110.975 1.00 87.61  ? 50  GLU D O     1 
ATOM   3629 C CB    . GLU B 2 50  ? 150.151 118.457 112.462 1.00 117.67 ? 50  GLU D CB    1 
ATOM   3630 C CG    . GLU B 2 50  ? 151.294 119.034 113.202 1.00 117.67 ? 50  GLU D CG    1 
ATOM   3631 C CD    . GLU B 2 50  ? 151.885 120.125 112.408 1.00 117.67 ? 50  GLU D CD    1 
ATOM   3632 O OE1   . GLU B 2 50  ? 151.371 121.238 112.469 1.00 117.67 ? 50  GLU D OE1   1 
ATOM   3633 O OE2   . GLU B 2 50  ? 152.816 119.847 111.650 1.00 117.67 ? 50  GLU D OE2   1 
ATOM   3634 N N     . LYS B 2 51  ? 152.687 117.089 111.239 1.00 87.56  ? 51  LYS D N     1 
ATOM   3635 C CA    . LYS B 2 51  ? 153.691 116.037 111.271 1.00 87.56  ? 51  LYS D CA    1 
ATOM   3636 C C     . LYS B 2 51  ? 153.932 115.454 112.649 1.00 87.56  ? 51  LYS D C     1 
ATOM   3637 O O     . LYS B 2 51  ? 154.218 116.181 113.594 1.00 87.56  ? 51  LYS D O     1 
ATOM   3638 C CB    . LYS B 2 51  ? 155.019 116.567 110.765 1.00 131.22 ? 51  LYS D CB    1 
ATOM   3639 C CG    . LYS B 2 51  ? 155.036 116.950 109.318 1.00 131.22 ? 51  LYS D CG    1 
ATOM   3640 C CD    . LYS B 2 51  ? 156.399 117.514 108.902 1.00 131.22 ? 51  LYS D CD    1 
ATOM   3641 C CE    . LYS B 2 51  ? 156.452 117.880 107.406 1.00 131.22 ? 51  LYS D CE    1 
ATOM   3642 N NZ    . LYS B 2 51  ? 155.627 119.088 107.057 1.00 131.22 ? 51  LYS D NZ    1 
ATOM   3643 N N     . ALA B 2 52  ? 153.896 114.137 112.741 1.00 87.10  ? 52  ALA D N     1 
ATOM   3644 C CA    . ALA B 2 52  ? 154.358 113.442 113.918 1.00 87.10  ? 52  ALA D CA    1 
ATOM   3645 C C     . ALA B 2 52  ? 155.848 113.481 113.876 1.00 87.10  ? 52  ALA D C     1 
ATOM   3646 O O     . ALA B 2 52  ? 156.429 113.751 112.829 1.00 87.10  ? 52  ALA D O     1 
ATOM   3647 C CB    . ALA B 2 52  ? 153.921 111.994 113.932 1.00 118.77 ? 52  ALA D CB    1 
ATOM   3648 N N     . SER B 2 53  ? 156.496 113.191 114.989 1.00 87.15  ? 53  SER D N     1 
ATOM   3649 C CA    . SER B 2 53  ? 157.948 113.187 114.901 1.00 87.15  ? 53  SER D CA    1 
ATOM   3650 C C     . SER B 2 53  ? 158.443 112.153 113.895 1.00 87.15  ? 53  SER D C     1 
ATOM   3651 O O     . SER B 2 53  ? 159.472 112.368 113.237 1.00 87.15  ? 53  SER D O     1 
ATOM   3652 C CB    . SER B 2 53  ? 158.550 112.916 116.263 1.00 117.38 ? 53  SER D CB    1 
ATOM   3653 O OG    . SER B 2 53  ? 158.206 111.614 116.675 1.00 117.38 ? 53  SER D OG    1 
ATOM   3654 N N     . ILE B 2 54  ? 157.733 111.032 113.741 1.00 85.28  ? 54  ILE D N     1 
ATOM   3655 C CA    . ILE B 2 54  ? 158.153 110.017 112.778 1.00 85.28  ? 54  ILE D CA    1 
ATOM   3656 C C     . ILE B 2 54  ? 156.987 109.527 111.929 1.00 85.28  ? 54  ILE D C     1 
ATOM   3657 O O     . ILE B 2 54  ? 156.108 108.828 112.430 1.00 85.28  ? 54  ILE D O     1 
ATOM   3658 C CB    . ILE B 2 54  ? 158.832 108.818 113.458 1.00 126.18 ? 54  ILE D CB    1 
ATOM   3659 C CG1   . ILE B 2 54  ? 160.065 109.275 114.268 1.00 126.18 ? 54  ILE D CG1   1 
ATOM   3660 C CG2   . ILE B 2 54  ? 159.207 107.774 112.388 1.00 126.18 ? 54  ILE D CG2   1 
ATOM   3661 C CD1   . ILE B 2 54  ? 160.711 108.198 115.125 1.00 126.18 ? 54  ILE D CD1   1 
ATOM   3662 N N     . GLY B 2 55  ? 157.005 109.838 110.640 1.00 87.39  ? 55  GLY D N     1 
ATOM   3663 C CA    . GLY B 2 55  ? 156.049 109.265 109.705 1.00 87.39  ? 55  GLY D CA    1 
ATOM   3664 C C     . GLY B 2 55  ? 154.609 109.751 109.774 1.00 87.39  ? 55  GLY D C     1 
ATOM   3665 O O     . GLY B 2 55  ? 154.079 110.340 108.832 1.00 87.39  ? 55  GLY D O     1 
ATOM   3666 N N     . LYS B 2 56  ? 153.977 109.488 110.907 1.00 89.74  ? 56  LYS D N     1 
ATOM   3667 C CA    . LYS B 2 56  ? 152.547 109.662 111.116 1.00 89.74  ? 56  LYS D CA    1 
ATOM   3668 C C     . LYS B 2 56  ? 152.038 111.077 110.888 1.00 89.74  ? 56  LYS D C     1 
ATOM   3669 O O     . LYS B 2 56  ? 152.651 112.066 111.279 1.00 89.74  ? 56  LYS D O     1 
ATOM   3670 C CB    . LYS B 2 56  ? 152.223 109.203 112.535 1.00 134.49 ? 56  LYS D CB    1 
ATOM   3671 C CG    . LYS B 2 56  ? 150.780 109.352 112.984 1.00 134.49 ? 56  LYS D CG    1 
ATOM   3672 C CD    . LYS B 2 56  ? 150.625 108.863 114.428 1.00 134.49 ? 56  LYS D CD    1 
ATOM   3673 C CE    . LYS B 2 56  ? 149.219 109.117 114.989 1.00 134.49 ? 56  LYS D CE    1 
ATOM   3674 N NZ    . LYS B 2 56  ? 148.209 108.153 114.467 1.00 134.49 ? 56  LYS D NZ    1 
ATOM   3675 N N     . TRP B 2 57  ? 150.879 111.159 110.273 1.00 87.88  ? 57  TRP D N     1 
ATOM   3676 C CA    . TRP B 2 57  ? 150.214 112.410 110.065 1.00 87.88  ? 57  TRP D CA    1 
ATOM   3677 C C     . TRP B 2 57  ? 149.026 112.569 111.002 1.00 87.88  ? 57  TRP D C     1 
ATOM   3678 O O     . TRP B 2 57  ? 148.311 111.614 111.284 1.00 87.88  ? 57  TRP D O     1 
ATOM   3679 C CB    . TRP B 2 57  ? 149.814 112.493 108.612 1.00 121.62 ? 57  TRP D CB    1 
ATOM   3680 C CG    . TRP B 2 57  ? 151.010 112.623 107.783 1.00 121.62 ? 57  TRP D CG    1 
ATOM   3681 C CD1   . TRP B 2 57  ? 151.690 111.636 107.195 1.00 121.62 ? 57  TRP D CD1   1 
ATOM   3682 C CD2   . TRP B 2 57  ? 151.690 113.817 107.469 1.00 121.62 ? 57  TRP D CD2   1 
ATOM   3683 N NE1   . TRP B 2 57  ? 152.748 112.147 106.518 1.00 121.62 ? 57  TRP D NE1   1 
ATOM   3684 C CE2   . TRP B 2 57  ? 152.751 113.494 106.674 1.00 121.62 ? 57  TRP D CE2   1 
ATOM   3685 C CE3   . TRP B 2 57  ? 151.478 115.134 107.775 1.00 121.62 ? 57  TRP D CE3   1 
ATOM   3686 C CZ2   . TRP B 2 57  ? 153.601 114.405 106.210 1.00 121.62 ? 57  TRP D CZ2   1 
ATOM   3687 C CZ3   . TRP B 2 57  ? 152.318 116.044 107.291 1.00 121.62 ? 57  TRP D CZ3   1 
ATOM   3688 C CH2   . TRP B 2 57  ? 153.371 115.682 106.523 1.00 121.62 ? 57  TRP D CH2   1 
ATOM   3689 N N     . ILE B 2 58  ? 148.814 113.790 111.472 1.00 82.03  ? 58  ILE D N     1 
ATOM   3690 C CA    . ILE B 2 58  ? 147.775 114.132 112.437 1.00 82.03  ? 58  ILE D CA    1 
ATOM   3691 C C     . ILE B 2 58  ? 146.801 115.123 111.818 1.00 82.03  ? 58  ILE D C     1 
ATOM   3692 O O     . ILE B 2 58  ? 147.216 116.194 111.393 1.00 82.03  ? 58  ILE D O     1 
ATOM   3693 C CB    . ILE B 2 58  ? 148.401 114.766 113.680 1.00 121.37 ? 58  ILE D CB    1 
ATOM   3694 C CG1   . ILE B 2 58  ? 149.325 113.799 114.338 1.00 121.37 ? 58  ILE D CG1   1 
ATOM   3695 C CG2   . ILE B 2 58  ? 147.403 115.295 114.608 1.00 121.37 ? 58  ILE D CG2   1 
ATOM   3696 C CD1   . ILE B 2 58  ? 150.773 114.035 114.018 1.00 121.37 ? 58  ILE D CD1   1 
ATOM   3697 N N     . PRO B 2 59  ? 145.532 114.869 111.801 1.00 82.06  ? 59  PRO D N     1 
ATOM   3698 C CA    . PRO B 2 59  ? 144.590 115.842 111.300 1.00 82.06  ? 59  PRO D CA    1 
ATOM   3699 C C     . PRO B 2 59  ? 144.680 117.100 112.109 1.00 82.06  ? 59  PRO D C     1 
ATOM   3700 O O     . PRO B 2 59  ? 144.585 117.044 113.324 1.00 82.06  ? 59  PRO D O     1 
ATOM   3701 C CB    . PRO B 2 59  ? 143.269 115.172 111.546 1.00 255.94 ? 59  PRO D CB    1 
ATOM   3702 C CG    . PRO B 2 59  ? 143.543 114.306 112.707 1.00 255.94 ? 59  PRO D CG    1 
ATOM   3703 C CD    . PRO B 2 59  ? 144.911 113.797 112.517 1.00 255.94 ? 59  PRO D CD    1 
ATOM   3704 N N     . ARG B 2 60  ? 144.770 118.258 111.470 1.00 87.10  ? 60  ARG D N     1 
ATOM   3705 C CA    . ARG B 2 60  ? 144.880 119.488 112.263 1.00 87.10  ? 60  ARG D CA    1 
ATOM   3706 C C     . ARG B 2 60  ? 143.502 119.969 112.689 1.00 87.10  ? 60  ARG D C     1 
ATOM   3707 O O     . ARG B 2 60  ? 142.969 120.929 112.147 1.00 87.10  ? 60  ARG D O     1 
ATOM   3708 C CB    . ARG B 2 60  ? 145.611 120.559 111.481 1.00 127.88 ? 60  ARG D CB    1 
ATOM   3709 C CG    . ARG B 2 60  ? 145.970 121.752 112.285 1.00 127.88 ? 60  ARG D CG    1 
ATOM   3710 C CD    . ARG B 2 60  ? 146.802 122.759 111.518 1.00 127.88 ? 60  ARG D CD    1 
ATOM   3711 N NE    . ARG B 2 60  ? 148.140 122.284 111.185 1.00 127.88 ? 60  ARG D NE    1 
ATOM   3712 C CZ    . ARG B 2 60  ? 148.556 121.995 109.970 1.00 127.88 ? 60  ARG D CZ    1 
ATOM   3713 N NH1   . ARG B 2 60  ? 147.758 122.056 108.931 1.00 127.88 ? 60  ARG D NH1   1 
ATOM   3714 N NH2   . ARG B 2 60  ? 149.802 121.617 109.786 1.00 127.88 ? 60  ARG D NH2   1 
ATOM   3715 N N     . THR B 2 61  ? 142.926 119.282 113.675 1.00 87.37  ? 61  THR D N     1 
ATOM   3716 C CA    . THR B 2 61  ? 141.557 119.517 114.110 1.00 87.37  ? 61  THR D CA    1 
ATOM   3717 C C     . THR B 2 61  ? 141.298 119.609 115.582 1.00 87.37  ? 61  THR D C     1 
ATOM   3718 O O     . THR B 2 61  ? 141.907 118.929 116.403 1.00 87.37  ? 61  THR D O     1 
ATOM   3719 C CB    . THR B 2 61  ? 140.618 118.401 113.794 1.00 122.30 ? 61  THR D CB    1 
ATOM   3720 O OG1   . THR B 2 61  ? 141.053 117.229 114.481 1.00 122.30 ? 61  THR D OG1   1 
ATOM   3721 C CG2   . THR B 2 61  ? 140.590 118.155 112.415 1.00 122.30 ? 61  THR D CG2   1 
ATOM   3722 N N     . ILE B 2 62  ? 140.213 120.304 115.857 1.00 85.92  ? 62  ILE D N     1 
ATOM   3723 C CA    . ILE B 2 62  ? 139.604 120.398 117.169 1.00 85.92  ? 62  ILE D CA    1 
ATOM   3724 C C     . ILE B 2 62  ? 138.148 119.954 117.086 1.00 85.92  ? 62  ILE D C     1 
ATOM   3725 O O     . ILE B 2 62  ? 137.429 120.373 116.181 1.00 85.92  ? 62  ILE D O     1 
ATOM   3726 C CB    . ILE B 2 62  ? 139.731 121.825 117.699 1.00 127.13 ? 62  ILE D CB    1 
ATOM   3727 C CG1   . ILE B 2 62  ? 141.212 122.159 117.829 1.00 127.13 ? 62  ILE D CG1   1 
ATOM   3728 C CG2   . ILE B 2 62  ? 139.010 121.977 119.007 1.00 127.13 ? 62  ILE D CG2   1 
ATOM   3729 C CD1   . ILE B 2 62  ? 141.534 123.597 118.089 1.00 127.13 ? 62  ILE D CD1   1 
ATOM   3730 N N     . LEU B 2 63  ? 137.700 119.109 118.009 1.00 82.68  ? 63  LEU D N     1 
ATOM   3731 C CA    . LEU B 2 63  ? 136.300 118.694 118.034 1.00 82.68  ? 63  LEU D CA    1 
ATOM   3732 C C     . LEU B 2 63  ? 135.610 119.282 119.252 1.00 82.68  ? 63  LEU D C     1 
ATOM   3733 O O     . LEU B 2 63  ? 135.992 118.963 120.369 1.00 82.68  ? 63  LEU D O     1 
ATOM   3734 C CB    . LEU B 2 63  ? 136.135 117.188 118.065 1.00 122.34 ? 63  LEU D CB    1 
ATOM   3735 C CG    . LEU B 2 63  ? 136.748 116.283 117.018 1.00 122.34 ? 63  LEU D CG    1 
ATOM   3736 C CD1   . LEU B 2 63  ? 136.368 114.855 117.309 1.00 122.34 ? 63  LEU D CD1   1 
ATOM   3737 C CD2   . LEU B 2 63  ? 136.353 116.649 115.652 1.00 122.34 ? 63  LEU D CD2   1 
ATOM   3738 N N     . VAL B 2 64  ? 134.574 120.090 119.060 1.00 82.49  ? 64  VAL D N     1 
ATOM   3739 C CA    . VAL B 2 64  ? 133.900 120.765 120.167 1.00 82.49  ? 64  VAL D CA    1 
ATOM   3740 C C     . VAL B 2 64  ? 132.447 120.352 120.260 1.00 82.49  ? 64  VAL D C     1 
ATOM   3741 O O     . VAL B 2 64  ? 131.680 120.606 119.333 1.00 82.49  ? 64  VAL D O     1 
ATOM   3742 C CB    . VAL B 2 64  ? 133.959 122.274 120.007 1.00 119.95 ? 64  VAL D CB    1 
ATOM   3743 C CG1   . VAL B 2 64  ? 133.307 122.928 121.175 1.00 119.95 ? 64  VAL D CG1   1 
ATOM   3744 C CG2   . VAL B 2 64  ? 135.370 122.729 119.849 1.00 119.95 ? 64  VAL D CG2   1 
ATOM   3745 N N     . ASP B 2 65  ? 132.044 119.773 121.382 1.00 84.11  ? 65  ASP D N     1 
ATOM   3746 C CA    . ASP B 2 65  ? 130.652 119.398 121.554 1.00 84.11  ? 65  ASP D CA    1 
ATOM   3747 C C     . ASP B 2 65  ? 130.256 119.481 122.997 1.00 84.11  ? 65  ASP D C     1 
ATOM   3748 O O     . ASP B 2 65  ? 130.843 118.814 123.845 1.00 84.11  ? 65  ASP D O     1 
ATOM   3749 C CB    . ASP B 2 65  ? 130.346 118.006 121.061 1.00 108.14 ? 65  ASP D CB    1 
ATOM   3750 C CG    . ASP B 2 65  ? 128.858 117.752 121.023 1.00 108.14 ? 65  ASP D CG    1 
ATOM   3751 O OD1   . ASP B 2 65  ? 128.116 118.625 121.504 1.00 108.14 ? 65  ASP D OD1   1 
ATOM   3752 O OD2   . ASP B 2 65  ? 128.412 116.714 120.507 1.00 108.14 ? 65  ASP D OD2   1 
ATOM   3753 N N     . LEU B 2 66  ? 129.235 120.256 123.263 1.00 80.55  ? 66  LEU D N     1 
ATOM   3754 C CA    . LEU B 2 66  ? 128.784 120.413 124.621 1.00 80.55  ? 66  LEU D CA    1 
ATOM   3755 C C     . LEU B 2 66  ? 128.195 119.119 125.131 1.00 80.55  ? 66  LEU D C     1 
ATOM   3756 O O     . LEU B 2 66  ? 128.309 118.823 126.317 1.00 80.55  ? 66  LEU D O     1 
ATOM   3757 C CB    . LEU B 2 66  ? 127.812 121.581 124.703 1.00 119.18 ? 66  LEU D CB    1 
ATOM   3758 C CG    . LEU B 2 66  ? 128.408 122.957 124.399 1.00 119.18 ? 66  LEU D CG    1 
ATOM   3759 C CD1   . LEU B 2 66  ? 127.304 123.993 124.298 1.00 119.18 ? 66  LEU D CD1   1 
ATOM   3760 C CD2   . LEU B 2 66  ? 129.412 123.376 125.402 1.00 119.18 ? 66  LEU D CD2   1 
ATOM   3761 N N     . GLY B 2 67  ? 127.580 118.320 124.278 1.00 81.99  ? 67  GLY D N     1 
ATOM   3762 C CA    . GLY B 2 67  ? 127.124 117.024 124.722 1.00 81.99  ? 67  GLY D CA    1 
ATOM   3763 C C     . GLY B 2 67  ? 128.216 116.028 124.401 1.00 81.99  ? 67  GLY D C     1 
ATOM   3764 O O     . GLY B 2 67  ? 128.908 116.176 123.411 1.00 81.99  ? 67  GLY D O     1 
ATOM   3765 N N     . PRO B 2 68  ? 128.389 114.980 125.176 1.00 82.61  ? 68  PRO D N     1 
ATOM   3766 C CA    . PRO B 2 68  ? 129.498 114.072 124.963 1.00 82.61  ? 68  PRO D CA    1 
ATOM   3767 C C     . PRO B 2 68  ? 129.299 113.086 123.856 1.00 82.61  ? 68  PRO D C     1 
ATOM   3768 O O     . PRO B 2 68  ? 130.260 112.414 123.469 1.00 82.61  ? 68  PRO D O     1 
ATOM   3769 C CB    . PRO B 2 68  ? 129.590 113.355 126.280 1.00 257.66 ? 68  PRO D CB    1 
ATOM   3770 C CG    . PRO B 2 68  ? 128.213 113.385 126.776 1.00 257.66 ? 68  PRO D CG    1 
ATOM   3771 C CD    . PRO B 2 68  ? 127.622 114.679 126.354 1.00 257.66 ? 68  PRO D CD    1 
ATOM   3772 N N     . ASN B 2 69  ? 128.106 112.963 123.304 1.00 85.78  ? 69  ASN D N     1 
ATOM   3773 C CA    . ASN B 2 69  ? 127.852 111.834 122.409 1.00 85.78  ? 69  ASN D CA    1 
ATOM   3774 C C     . ASN B 2 69  ? 128.499 111.945 121.031 1.00 85.78  ? 69  ASN D C     1 
ATOM   3775 O O     . ASN B 2 69  ? 128.968 110.934 120.494 1.00 85.78  ? 69  ASN D O     1 
ATOM   3776 C CB    . ASN B 2 69  ? 126.377 111.638 122.265 1.00 116.21 ? 69  ASN D CB    1 
ATOM   3777 C CG    . ASN B 2 69  ? 125.793 111.051 123.492 1.00 116.21 ? 69  ASN D CG    1 
ATOM   3778 O OD1   . ASN B 2 69  ? 126.493 110.446 124.306 1.00 116.21 ? 69  ASN D OD1   1 
ATOM   3779 N ND2   . ASN B 2 69  ? 124.507 111.227 123.657 1.00 116.21 ? 69  ASN D ND2   1 
ATOM   3780 N N     . ALA B 2 70  ? 128.516 113.114 120.403 1.00 83.35  ? 70  ALA D N     1 
ATOM   3781 C CA    . ALA B 2 70  ? 129.075 113.100 119.065 1.00 83.35  ? 70  ALA D CA    1 
ATOM   3782 C C     . ALA B 2 70  ? 130.534 112.755 119.128 1.00 83.35  ? 70  ALA D C     1 
ATOM   3783 O O     . ALA B 2 70  ? 131.042 111.999 118.292 1.00 83.35  ? 70  ALA D O     1 
ATOM   3784 C CB    . ALA B 2 70  ? 128.875 114.438 118.370 1.00 113.66 ? 70  ALA D CB    1 
ATOM   3785 N N     . ILE B 2 71  ? 131.213 113.264 120.134 1.00 83.16  ? 71  ILE D N     1 
ATOM   3786 C CA    . ILE B 2 71  ? 132.624 113.030 120.216 1.00 83.16  ? 71  ILE D CA    1 
ATOM   3787 C C     . ILE B 2 71  ? 132.897 111.612 120.614 1.00 83.16  ? 71  ILE D C     1 
ATOM   3788 O O     . ILE B 2 71  ? 133.806 110.985 120.066 1.00 83.16  ? 71  ILE D O     1 
ATOM   3789 C CB    . ILE B 2 71  ? 133.318 114.016 121.134 1.00 123.04 ? 71  ILE D CB    1 
ATOM   3790 C CG1   . ILE B 2 71  ? 133.259 115.374 120.506 1.00 123.04 ? 71  ILE D CG1   1 
ATOM   3791 C CG2   . ILE B 2 71  ? 134.755 113.589 121.316 1.00 123.04 ? 71  ILE D CG2   1 
ATOM   3792 C CD1   . ILE B 2 71  ? 133.716 116.540 121.390 1.00 123.04 ? 71  ILE D CD1   1 
ATOM   3793 N N     . ARG B 2 72  ? 132.156 111.071 121.565 1.00 85.33  ? 72  ARG D N     1 
ATOM   3794 C CA    . ARG B 2 72  ? 132.469 109.716 121.988 1.00 85.33  ? 72  ARG D CA    1 
ATOM   3795 C C     . ARG B 2 72  ? 132.303 108.727 120.859 1.00 85.33  ? 72  ARG D C     1 
ATOM   3796 O O     . ARG B 2 72  ? 133.134 107.830 120.717 1.00 85.33  ? 72  ARG D O     1 
ATOM   3797 C CB    . ARG B 2 72  ? 131.638 109.308 123.187 1.00 125.28 ? 72  ARG D CB    1 
ATOM   3798 C CG    . ARG B 2 72  ? 132.121 109.969 124.464 1.00 125.28 ? 72  ARG D CG    1 
ATOM   3799 C CD    . ARG B 2 72  ? 131.277 109.687 125.682 1.00 125.28 ? 72  ARG D CD    1 
ATOM   3800 N NE    . ARG B 2 72  ? 131.878 110.303 126.863 1.00 125.28 ? 72  ARG D NE    1 
ATOM   3801 C CZ    . ARG B 2 72  ? 131.276 110.502 128.031 1.00 125.28 ? 72  ARG D CZ    1 
ATOM   3802 N NH1   . ARG B 2 72  ? 130.012 110.172 128.232 1.00 125.28 ? 72  ARG D NH1   1 
ATOM   3803 N NH2   . ARG B 2 72  ? 131.961 111.055 129.028 1.00 125.28 ? 72  ARG D NH2   1 
ATOM   3804 N N     . LYS B 2 73  ? 131.273 108.858 120.016 1.00 85.79  ? 73  LYS D N     1 
ATOM   3805 C CA    . LYS B 2 73  ? 131.242 107.832 118.984 1.00 85.79  ? 73  LYS D CA    1 
ATOM   3806 C C     . LYS B 2 73  ? 132.302 108.093 117.932 1.00 85.79  ? 73  LYS D C     1 
ATOM   3807 O O     . LYS B 2 73  ? 132.922 107.159 117.439 1.00 85.79  ? 73  LYS D O     1 
ATOM   3808 C CB    . LYS B 2 73  ? 129.854 107.675 118.380 1.00 128.57 ? 73  LYS D CB    1 
ATOM   3809 C CG    . LYS B 2 73  ? 129.440 108.703 117.450 1.00 128.57 ? 73  LYS D CG    1 
ATOM   3810 C CD    . LYS B 2 73  ? 128.009 108.518 116.995 1.00 128.57 ? 73  LYS D CD    1 
ATOM   3811 C CE    . LYS B 2 73  ? 127.853 107.556 115.849 1.00 128.57 ? 73  LYS D CE    1 
ATOM   3812 N NZ    . LYS B 2 73  ? 128.492 108.028 114.595 1.00 128.57 ? 73  LYS D NZ    1 
ATOM   3813 N N     . VAL B 2 74  ? 132.641 109.341 117.664 1.00 83.87  ? 74  VAL D N     1 
ATOM   3814 C CA    . VAL B 2 74  ? 133.668 109.544 116.663 1.00 83.87  ? 74  VAL D CA    1 
ATOM   3815 C C     . VAL B 2 74  ? 134.984 108.982 117.091 1.00 83.87  ? 74  VAL D C     1 
ATOM   3816 O O     . VAL B 2 74  ? 135.675 108.356 116.294 1.00 83.87  ? 74  VAL D O     1 
ATOM   3817 C CB    . VAL B 2 74  ? 133.805 111.013 116.316 1.00 121.95 ? 74  VAL D CB    1 
ATOM   3818 C CG1   . VAL B 2 74  ? 135.060 111.253 115.542 1.00 121.95 ? 74  VAL D CG1   1 
ATOM   3819 C CG2   . VAL B 2 74  ? 132.630 111.386 115.498 1.00 121.95 ? 74  VAL D CG2   1 
ATOM   3820 N N     . THR B 2 75  ? 135.368 109.179 118.325 1.00 84.56  ? 75  THR D N     1 
ATOM   3821 C CA    . THR B 2 75  ? 136.689 108.722 118.702 1.00 84.56  ? 75  THR D CA    1 
ATOM   3822 C C     . THR B 2 75  ? 136.727 107.278 119.166 1.00 84.56  ? 75  THR D C     1 
ATOM   3823 O O     . THR B 2 75  ? 137.813 106.691 119.204 1.00 84.56  ? 75  THR D O     1 
ATOM   3824 C CB    . THR B 2 75  ? 137.299 109.634 119.779 1.00 118.37 ? 75  THR D CB    1 
ATOM   3825 O OG1   . THR B 2 75  ? 136.535 109.560 120.988 1.00 118.37 ? 75  THR D OG1   1 
ATOM   3826 C CG2   . THR B 2 75  ? 137.304 111.081 119.291 1.00 118.37 ? 75  THR D CG2   1 
ATOM   3827 N N     . LYS B 2 76  ? 135.601 106.666 119.495 1.00 87.35  ? 76  LYS D N     1 
ATOM   3828 C CA    . LYS B 2 76  ? 135.641 105.271 119.890 1.00 87.35  ? 76  LYS D CA    1 
ATOM   3829 C C     . LYS B 2 76  ? 135.110 104.303 118.845 1.00 87.35  ? 76  LYS D C     1 
ATOM   3830 O O     . LYS B 2 76  ? 135.498 103.146 118.859 1.00 87.35  ? 76  LYS D O     1 
ATOM   3831 C CB    . LYS B 2 76  ? 134.857 105.065 121.184 1.00 130.91 ? 76  LYS D CB    1 
ATOM   3832 C CG    . LYS B 2 76  ? 135.370 105.838 122.386 1.00 130.91 ? 76  LYS D CG    1 
ATOM   3833 C CD    . LYS B 2 76  ? 136.774 105.404 122.802 1.00 130.91 ? 76  LYS D CD    1 
ATOM   3834 C CE    . LYS B 2 76  ? 137.216 106.089 124.096 1.00 130.91 ? 76  LYS D CE    1 
ATOM   3835 N NZ    . LYS B 2 76  ? 138.597 105.690 124.497 1.00 130.91 ? 76  LYS D NZ    1 
ATOM   3836 N N     . LYS B 2 77  ? 134.233 104.718 117.962 1.00 88.63  ? 77  LYS D N     1 
ATOM   3837 C CA    . LYS B 2 77  ? 133.653 103.814 117.002 1.00 88.63  ? 77  LYS D CA    1 
ATOM   3838 C C     . LYS B 2 77  ? 133.939 104.151 115.547 1.00 88.63  ? 77  LYS D C     1 
ATOM   3839 O O     . LYS B 2 77  ? 134.184 103.246 114.757 1.00 88.63  ? 77  LYS D O     1 
ATOM   3840 C CB    . LYS B 2 77  ? 132.150 103.769 117.202 1.00 132.83 ? 77  LYS D CB    1 
ATOM   3841 C CG    . LYS B 2 77  ? 131.688 103.351 118.589 1.00 132.83 ? 77  LYS D CG    1 
ATOM   3842 C CD    . LYS B 2 77  ? 132.052 101.908 118.932 1.00 132.83 ? 77  LYS D CD    1 
ATOM   3843 C CE    . LYS B 2 77  ? 131.455 101.488 120.276 1.00 132.83 ? 77  LYS D CE    1 
ATOM   3844 N NZ    . LYS B 2 77  ? 131.814 100.086 120.650 1.00 132.83 ? 77  LYS D NZ    1 
ATOM   3845 N N     . ASP B 2 78  ? 133.928 105.426 115.150 1.00 87.32  ? 78  ASP D N     1 
ATOM   3846 C CA    . ASP B 2 78  ? 134.045 105.747 113.725 1.00 87.32  ? 78  ASP D CA    1 
ATOM   3847 C C     . ASP B 2 78  ? 135.479 105.856 113.202 1.00 87.32  ? 78  ASP D C     1 
ATOM   3848 O O     . ASP B 2 78  ? 135.746 105.436 112.074 1.00 87.32  ? 78  ASP D O     1 
ATOM   3849 C CB    . ASP B 2 78  ? 133.337 107.066 113.408 1.00 112.27 ? 78  ASP D CB    1 
ATOM   3850 C CG    . ASP B 2 78  ? 131.828 107.007 113.598 1.00 112.27 ? 78  ASP D CG    1 
ATOM   3851 O OD1   . ASP B 2 78  ? 131.172 106.207 112.928 1.00 112.27 ? 78  ASP D OD1   1 
ATOM   3852 O OD2   . ASP B 2 78  ? 131.297 107.783 114.408 1.00 112.27 ? 78  ASP D OD2   1 
ATOM   3853 N N     . MET B 2 79  ? 136.413 106.431 113.960 1.00 86.74  ? 79  MET D N     1 
ATOM   3854 C CA    . MET B 2 79  ? 137.765 106.597 113.436 1.00 86.74  ? 79  MET D CA    1 
ATOM   3855 C C     . MET B 2 79  ? 138.734 106.657 114.598 1.00 86.74  ? 79  MET D C     1 
ATOM   3856 O O     . MET B 2 79  ? 138.843 107.674 115.275 1.00 86.74  ? 79  MET D O     1 
ATOM   3857 C CB    . MET B 2 79  ? 137.836 107.838 112.569 1.00 124.57 ? 79  MET D CB    1 
ATOM   3858 C CG    . MET B 2 79  ? 139.102 108.022 111.790 1.00 124.57 ? 79  MET D CG    1 
ATOM   3859 S SD    . MET B 2 79  ? 138.954 109.387 110.642 1.00 124.57 ? 79  MET D SD    1 
ATOM   3860 C CE    . MET B 2 79  ? 140.319 109.122 109.524 1.00 124.57 ? 79  MET D CE    1 
ATOM   3861 N N     . LYS B 2 80  ? 139.429 105.588 114.821 1.00 84.59  ? 80  LYS D N     1 
ATOM   3862 C CA    . LYS B 2 80  ? 140.250 105.502 116.007 1.00 84.59  ? 80  LYS D CA    1 
ATOM   3863 C C     . LYS B 2 80  ? 141.631 106.093 115.820 1.00 84.59  ? 80  LYS D C     1 
ATOM   3864 O O     . LYS B 2 80  ? 142.156 106.145 114.713 1.00 84.59  ? 80  LYS D O     1 
ATOM   3865 C CB    . LYS B 2 80  ? 140.369 104.046 116.421 1.00 126.77 ? 80  LYS D CB    1 
ATOM   3866 C CG    . LYS B 2 80  ? 139.050 103.439 116.863 1.00 126.77 ? 80  LYS D CG    1 
ATOM   3867 C CD    . LYS B 2 80  ? 139.214 101.980 117.243 1.00 126.77 ? 80  LYS D CD    1 
ATOM   3868 C CE    . LYS B 2 80  ? 137.915 101.396 117.738 1.00 126.77 ? 80  LYS D CE    1 
ATOM   3869 N NZ    . LYS B 2 80  ? 138.038 99.947  118.041 1.00 126.77 ? 80  LYS D NZ    1 
ATOM   3870 N N     . ASP B 2 81  ? 142.216 106.533 116.926 1.00 84.18  ? 81  ASP D N     1 
ATOM   3871 C CA    . ASP B 2 81  ? 143.614 106.954 116.996 1.00 84.18  ? 81  ASP D CA    1 
ATOM   3872 C C     . ASP B 2 81  ? 143.967 108.007 115.961 1.00 84.18  ? 81  ASP D C     1 
ATOM   3873 O O     . ASP B 2 81  ? 145.041 107.999 115.363 1.00 84.18  ? 81  ASP D O     1 
ATOM   3874 C CB    . ASP B 2 81  ? 144.512 105.748 116.887 1.00 108.23 ? 81  ASP D CB    1 
ATOM   3875 C CG    . ASP B 2 81  ? 144.216 104.766 117.990 1.00 108.23 ? 81  ASP D CG    1 
ATOM   3876 O OD1   . ASP B 2 81  ? 143.529 105.168 118.939 1.00 108.23 ? 81  ASP D OD1   1 
ATOM   3877 O OD2   . ASP B 2 81  ? 144.652 103.617 117.925 1.00 108.23 ? 81  ASP D OD2   1 
ATOM   3878 N N     . PHE B 2 82  ? 143.036 108.904 115.734 1.00 85.35  ? 82  PHE D N     1 
ATOM   3879 C CA    . PHE B 2 82  ? 143.206 109.953 114.764 1.00 85.35  ? 82  PHE D CA    1 
ATOM   3880 C C     . PHE B 2 82  ? 142.843 111.275 115.402 1.00 85.35  ? 82  PHE D C     1 
ATOM   3881 O O     . PHE B 2 82  ? 143.694 112.133 115.612 1.00 85.35  ? 82  PHE D O     1 
ATOM   3882 C CB    . PHE B 2 82  ? 142.316 109.574 113.597 1.00 119.05 ? 82  PHE D CB    1 
ATOM   3883 C CG    . PHE B 2 82  ? 142.408 110.431 112.432 1.00 119.05 ? 82  PHE D CG    1 
ATOM   3884 C CD1   . PHE B 2 82  ? 143.432 110.319 111.575 1.00 119.05 ? 82  PHE D CD1   1 
ATOM   3885 C CD2   . PHE B 2 82  ? 141.414 111.292 112.165 1.00 119.05 ? 82  PHE D CD2   1 
ATOM   3886 C CE1   . PHE B 2 82  ? 143.488 111.081 110.478 1.00 119.05 ? 82  PHE D CE1   1 
ATOM   3887 C CE2   . PHE B 2 82  ? 141.461 112.068 111.089 1.00 119.05 ? 82  PHE D CE2   1 
ATOM   3888 C CZ    . PHE B 2 82  ? 142.504 111.962 110.231 1.00 119.05 ? 82  PHE D CZ    1 
ATOM   3889 N N     . PHE B 2 83  ? 141.590 111.417 115.804 1.00 80.42  ? 83  PHE D N     1 
ATOM   3890 C CA    . PHE B 2 83  ? 141.130 112.650 116.406 1.00 80.42  ? 83  PHE D CA    1 
ATOM   3891 C C     . PHE B 2 83  ? 141.547 112.612 117.855 1.00 80.42  ? 83  PHE D C     1 
ATOM   3892 O O     . PHE B 2 83  ? 140.731 112.374 118.750 1.00 80.42  ? 83  PHE D O     1 
ATOM   3893 C CB    . PHE B 2 83  ? 139.634 112.775 116.343 1.00 112.17 ? 83  PHE D CB    1 
ATOM   3894 C CG    . PHE B 2 83  ? 139.076 112.853 115.017 1.00 112.17 ? 83  PHE D CG    1 
ATOM   3895 C CD1   . PHE B 2 83  ? 139.180 113.969 114.308 1.00 112.17 ? 83  PHE D CD1   1 
ATOM   3896 C CD2   . PHE B 2 83  ? 138.363 111.809 114.504 1.00 112.17 ? 83  PHE D CD2   1 
ATOM   3897 C CE1   . PHE B 2 83  ? 138.629 114.055 113.079 1.00 112.17 ? 83  PHE D CE1   1 
ATOM   3898 C CE2   . PHE B 2 83  ? 137.805 111.884 113.291 1.00 112.17 ? 83  PHE D CE2   1 
ATOM   3899 C CZ    . PHE B 2 83  ? 137.935 113.006 112.573 1.00 112.17 ? 83  PHE D CZ    1 
ATOM   3900 N N     . ASP B 2 84  ? 142.824 112.861 118.089 1.00 87.87  ? 84  ASP D N     1 
ATOM   3901 C CA    . ASP B 2 84  ? 143.452 112.753 119.402 1.00 87.87  ? 84  ASP D CA    1 
ATOM   3902 C C     . ASP B 2 84  ? 142.646 113.465 120.486 1.00 87.87  ? 84  ASP D C     1 
ATOM   3903 O O     . ASP B 2 84  ? 142.416 114.675 120.369 1.00 87.87  ? 84  ASP D O     1 
ATOM   3904 C CB    . ASP B 2 84  ? 144.858 113.350 119.342 1.00 112.97 ? 84  ASP D CB    1 
ATOM   3905 C CG    . ASP B 2 84  ? 145.665 113.167 120.638 1.00 112.97 ? 84  ASP D CG    1 
ATOM   3906 O OD1   . ASP B 2 84  ? 145.080 113.090 121.729 1.00 112.97 ? 84  ASP D OD1   1 
ATOM   3907 O OD2   . ASP B 2 84  ? 146.903 113.137 120.555 1.00 112.97 ? 84  ASP D OD2   1 
ATOM   3908 N N     . PRO B 2 85  ? 142.269 112.764 121.566 1.00 88.27  ? 85  PRO D N     1 
ATOM   3909 C CA    . PRO B 2 85  ? 141.458 113.293 122.669 1.00 88.27  ? 85  PRO D CA    1 
ATOM   3910 C C     . PRO B 2 85  ? 141.988 114.549 123.281 1.00 88.27  ? 85  PRO D C     1 
ATOM   3911 O O     . PRO B 2 85  ? 141.218 115.321 123.858 1.00 88.27  ? 85  PRO D O     1 
ATOM   3912 C CB    . PRO B 2 85  ? 141.510 112.159 123.683 1.00 275.32 ? 85  PRO D CB    1 
ATOM   3913 C CG    . PRO B 2 85  ? 141.681 110.949 122.858 1.00 275.32 ? 85  PRO D CG    1 
ATOM   3914 C CD    . PRO B 2 85  ? 142.541 111.344 121.710 1.00 275.32 ? 85  PRO D CD    1 
ATOM   3915 N N     . LYS B 2 86  ? 143.280 114.792 123.167 1.00 86.79  ? 86  LYS D N     1 
ATOM   3916 C CA    . LYS B 2 86  ? 143.843 116.005 123.719 1.00 86.79  ? 86  LYS D CA    1 
ATOM   3917 C C     . LYS B 2 86  ? 143.264 117.234 123.079 1.00 86.79  ? 86  LYS D C     1 
ATOM   3918 O O     . LYS B 2 86  ? 143.337 118.317 123.661 1.00 86.79  ? 86  LYS D O     1 
ATOM   3919 C CB    . LYS B 2 86  ? 145.348 116.047 123.546 1.00 130.07 ? 86  LYS D CB    1 
ATOM   3920 C CG    . LYS B 2 86  ? 146.135 115.040 124.367 1.00 130.07 ? 86  LYS D CG    1 
ATOM   3921 C CD    . LYS B 2 86  ? 147.654 115.301 124.307 1.00 130.07 ? 86  LYS D CD    1 
ATOM   3922 C CE    . LYS B 2 86  ? 148.274 115.009 122.919 1.00 130.07 ? 86  LYS D CE    1 
ATOM   3923 N NZ    . LYS B 2 86  ? 148.244 113.561 122.555 1.00 130.07 ? 86  LYS D NZ    1 
ATOM   3924 N N     . ARG B 2 87  ? 142.728 117.110 121.885 1.00 86.01  ? 87  ARG D N     1 
ATOM   3925 C CA    . ARG B 2 87  ? 142.174 118.239 121.171 1.00 86.01  ? 87  ARG D CA    1 
ATOM   3926 C C     . ARG B 2 87  ? 140.660 118.220 121.132 1.00 86.01  ? 87  ARG D C     1 
ATOM   3927 O O     . ARG B 2 87  ? 140.060 118.935 120.331 1.00 86.01  ? 87  ARG D O     1 
ATOM   3928 C CB    . ARG B 2 87  ? 142.716 118.279 119.764 1.00 126.28 ? 87  ARG D CB    1 
ATOM   3929 C CG    . ARG B 2 87  ? 144.196 118.510 119.701 1.00 126.28 ? 87  ARG D CG    1 
ATOM   3930 C CD    . ARG B 2 87  ? 144.635 118.740 118.292 1.00 126.28 ? 87  ARG D CD    1 
ATOM   3931 N NE    . ARG B 2 87  ? 144.291 117.612 117.447 1.00 126.28 ? 87  ARG D NE    1 
ATOM   3932 C CZ    . ARG B 2 87  ? 145.034 116.526 117.296 1.00 126.28 ? 87  ARG D CZ    1 
ATOM   3933 N NH1   . ARG B 2 87  ? 146.207 116.401 117.896 1.00 126.28 ? 87  ARG D NH1   1 
ATOM   3934 N NH2   . ARG B 2 87  ? 144.579 115.533 116.540 1.00 126.28 ? 87  ARG D NH2   1 
ATOM   3935 N N     . CYS B 2 88  ? 140.021 117.431 121.969 1.00 85.47  ? 88  CYS D N     1 
ATOM   3936 C CA    . CYS B 2 88  ? 138.576 117.428 122.021 1.00 85.47  ? 88  CYS D CA    1 
ATOM   3937 C C     . CYS B 2 88  ? 138.068 118.233 123.206 1.00 85.47  ? 88  CYS D C     1 
ATOM   3938 O O     . CYS B 2 88  ? 138.585 118.107 124.312 1.00 85.47  ? 88  CYS D O     1 
ATOM   3939 C CB    . CYS B 2 88  ? 138.069 116.007 122.103 1.00 115.12 ? 88  CYS D CB    1 
ATOM   3940 S SG    . CYS B 2 88  ? 138.499 115.037 120.652 1.00 115.12 ? 88  CYS D SG    1 
ATOM   3941 N N     . VAL B 2 89  ? 137.057 119.051 122.986 1.00 81.49  ? 89  VAL D N     1 
ATOM   3942 C CA    . VAL B 2 89  ? 136.456 119.825 124.044 1.00 81.49  ? 89  VAL D CA    1 
ATOM   3943 C C     . VAL B 2 89  ? 135.098 119.262 124.314 1.00 81.49  ? 89  VAL D C     1 
ATOM   3944 O O     . VAL B 2 89  ? 134.189 119.422 123.507 1.00 81.49  ? 89  VAL D O     1 
ATOM   3945 C CB    . VAL B 2 89  ? 136.324 121.274 123.667 1.00 118.49 ? 89  VAL D CB    1 
ATOM   3946 C CG1   . VAL B 2 89  ? 135.665 122.028 124.793 1.00 118.49 ? 89  VAL D CG1   1 
ATOM   3947 C CG2   . VAL B 2 89  ? 137.647 121.794 123.366 1.00 118.49 ? 89  VAL D CG2   1 
ATOM   3948 N N     . MET B 2 90  ? 134.925 118.640 125.451 1.00 82.96  ? 90  MET D N     1 
ATOM   3949 C CA    . MET B 2 90  ? 133.708 117.917 125.727 1.00 82.96  ? 90  MET D CA    1 
ATOM   3950 C C     . MET B 2 90  ? 132.975 118.459 126.926 1.00 82.96  ? 90  MET D C     1 
ATOM   3951 O O     . MET B 2 90  ? 133.541 118.567 128.008 1.00 82.96  ? 90  MET D O     1 
ATOM   3952 C CB    . MET B 2 90  ? 134.042 116.473 125.953 1.00 119.14 ? 90  MET D CB    1 
ATOM   3953 C CG    . MET B 2 90  ? 132.924 115.639 126.235 1.00 119.14 ? 90  MET D CG    1 
ATOM   3954 S SD    . MET B 2 90  ? 133.411 113.944 126.421 1.00 119.14 ? 90  MET D SD    1 
ATOM   3955 C CE    . MET B 2 90  ? 133.572 113.436 124.731 1.00 119.14 ? 90  MET D CE    1 
ATOM   3956 N N     . GLY B 2 91  ? 131.710 118.781 126.745 1.00 83.65  ? 91  GLY D N     1 
ATOM   3957 C CA    . GLY B 2 91  ? 130.865 119.192 127.839 1.00 83.65  ? 91  GLY D CA    1 
ATOM   3958 C C     . GLY B 2 91  ? 130.105 117.978 128.332 1.00 83.65  ? 91  GLY D C     1 
ATOM   3959 O O     . GLY B 2 91  ? 130.325 116.871 127.861 1.00 83.65  ? 91  GLY D O     1 
ATOM   3960 N N     . LEU B 2 92  ? 129.217 118.170 129.299 1.00 77.63  ? 92  LEU D N     1 
ATOM   3961 C CA    . LEU B 2 92  ? 128.445 117.038 129.780 1.00 77.63  ? 92  LEU D CA    1 
ATOM   3962 C C     . LEU B 2 92  ? 126.995 117.397 129.868 1.00 77.63  ? 92  LEU D C     1 
ATOM   3963 O O     . LEU B 2 92  ? 126.285 116.964 130.769 1.00 77.63  ? 92  LEU D O     1 
ATOM   3964 C CB    . LEU B 2 92  ? 128.926 116.555 131.118 1.00 114.86 ? 92  LEU D CB    1 
ATOM   3965 C CG    . LEU B 2 92  ? 130.298 115.973 131.162 1.00 114.86 ? 92  LEU D CG    1 
ATOM   3966 C CD1   . LEU B 2 92  ? 130.651 115.721 132.583 1.00 114.86 ? 92  LEU D CD1   1 
ATOM   3967 C CD2   . LEU B 2 92  ? 130.341 114.692 130.371 1.00 114.86 ? 92  LEU D CD2   1 
ATOM   3968 N N     . ALA B 2 93  ? 126.518 118.196 128.935 1.00 78.88  ? 93  ALA D N     1 
ATOM   3969 C CA    . ALA B 2 93  ? 125.124 118.565 128.960 1.00 78.88  ? 93  ALA D CA    1 
ATOM   3970 C C     . ALA B 2 93  ? 124.670 118.893 127.570 1.00 78.88  ? 93  ALA D C     1 
ATOM   3971 O O     . ALA B 2 93  ? 125.453 119.339 126.737 1.00 78.88  ? 93  ALA D O     1 
ATOM   3972 C CB    . ALA B 2 93  ? 124.921 119.769 129.845 1.00 107.56 ? 93  ALA D CB    1 
ATOM   3973 N N     . GLY B 2 94  ? 123.418 118.704 127.308 1.00 80.66  ? 94  GLY D N     1 
ATOM   3974 C CA    . GLY B 2 94  ? 122.925 119.101 126.019 1.00 80.66  ? 94  GLY D CA    1 
ATOM   3975 C C     . GLY B 2 94  ? 122.611 120.561 126.050 1.00 80.66  ? 94  GLY D C     1 
ATOM   3976 O O     . GLY B 2 94  ? 122.733 121.215 127.072 1.00 80.66  ? 94  GLY D O     1 
ATOM   3977 N N     . ASP B 2 95  ? 122.152 121.059 124.927 1.00 81.81  ? 95  ASP D N     1 
ATOM   3978 C CA    . ASP B 2 95  ? 121.732 122.424 124.783 1.00 81.81  ? 95  ASP D CA    1 
ATOM   3979 C C     . ASP B 2 95  ? 120.216 122.557 124.753 1.00 81.81  ? 95  ASP D C     1 
ATOM   3980 O O     . ASP B 2 95  ? 119.684 123.669 124.683 1.00 81.81  ? 95  ASP D O     1 
ATOM   3981 C CB    . ASP B 2 95  ? 122.316 122.899 123.494 1.00 105.18 ? 95  ASP D CB    1 
ATOM   3982 C CG    . ASP B 2 95  ? 121.921 121.967 122.405 1.00 105.18 ? 95  ASP D CG    1 
ATOM   3983 O OD1   . ASP B 2 95  ? 121.146 121.056 122.734 1.00 105.18 ? 95  ASP D OD1   1 
ATOM   3984 O OD2   . ASP B 2 95  ? 122.352 122.077 121.246 1.00 105.18 ? 95  ASP D OD2   1 
ATOM   3985 N N     . ALA B 2 96  ? 119.516 121.450 124.800 1.00 82.58  ? 96  ALA D N     1 
ATOM   3986 C CA    . ALA B 2 96  ? 118.080 121.433 124.638 1.00 82.58  ? 96  ALA D CA    1 
ATOM   3987 C C     . ALA B 2 96  ? 117.723 122.122 123.345 1.00 82.58  ? 96  ALA D C     1 
ATOM   3988 O O     . ALA B 2 96  ? 116.674 122.759 123.228 1.00 82.58  ? 96  ALA D O     1 
ATOM   3989 C CB    . ALA B 2 96  ? 117.361 122.071 125.824 1.00 112.61 ? 96  ALA D CB    1 
ATOM   3990 N N     . ASN B 2 97  ? 118.630 122.004 122.398 1.00 81.29  ? 97  ASN D N     1 
ATOM   3991 C CA    . ASN B 2 97  ? 118.567 122.564 121.070 1.00 81.29  ? 97  ASN D CA    1 
ATOM   3992 C C     . ASN B 2 97  ? 118.607 124.085 121.040 1.00 81.29  ? 97  ASN D C     1 
ATOM   3993 O O     . ASN B 2 97  ? 118.511 124.653 119.960 1.00 81.29  ? 97  ASN D O     1 
ATOM   3994 C CB    . ASN B 2 97  ? 117.345 122.105 120.322 1.00 110.13 ? 97  ASN D CB    1 
ATOM   3995 C CG    . ASN B 2 97  ? 117.324 120.647 120.079 1.00 110.13 ? 97  ASN D CG    1 
ATOM   3996 O OD1   . ASN B 2 97  ? 118.311 120.042 119.680 1.00 110.13 ? 97  ASN D OD1   1 
ATOM   3997 N ND2   . ASN B 2 97  ? 116.162 120.055 120.295 1.00 110.13 ? 97  ASN D ND2   1 
ATOM   3998 N N     . LEU B 2 98  ? 118.842 124.771 122.158 1.00 82.30  ? 98  LEU D N     1 
ATOM   3999 C CA    . LEU B 2 98  ? 118.799 126.240 122.206 1.00 82.30  ? 98  LEU D CA    1 
ATOM   4000 C C     . LEU B 2 98  ? 120.068 126.982 121.817 1.00 82.30  ? 98  LEU D C     1 
ATOM   4001 O O     . LEU B 2 98  ? 121.138 126.728 122.360 1.00 82.30  ? 98  LEU D O     1 
ATOM   4002 C CB    . LEU B 2 98  ? 118.490 126.702 123.610 1.00 121.77 ? 98  LEU D CB    1 
ATOM   4003 C CG    . LEU B 2 98  ? 117.168 126.368 124.219 1.00 121.77 ? 98  LEU D CG    1 
ATOM   4004 C CD1   . LEU B 2 98  ? 117.232 126.725 125.658 1.00 121.77 ? 98  LEU D CD1   1 
ATOM   4005 C CD2   . LEU B 2 98  ? 116.109 127.192 123.556 1.00 121.77 ? 98  LEU D CD2   1 
ATOM   4006 N N     . PHE B 2 99  ? 119.909 128.008 120.986 1.00 81.79  ? 99  PHE D N     1 
ATOM   4007 C CA    . PHE B 2 99  ? 121.008 128.889 120.638 1.00 81.79  ? 99  PHE D CA    1 
ATOM   4008 C C     . PHE B 2 99  ? 121.652 129.412 121.869 1.00 81.79  ? 99  PHE D C     1 
ATOM   4009 O O     . PHE B 2 99  ? 122.875 129.403 122.004 1.00 81.79  ? 99  PHE D O     1 
ATOM   4010 C CB    . PHE B 2 99  ? 120.510 130.060 119.806 1.00 114.08 ? 99  PHE D CB    1 
ATOM   4011 C CG    . PHE B 2 99  ? 121.520 131.106 119.531 1.00 114.08 ? 99  PHE D CG    1 
ATOM   4012 C CD1   . PHE B 2 99  ? 122.404 130.970 118.530 1.00 114.08 ? 99  PHE D CD1   1 
ATOM   4013 C CD2   . PHE B 2 99  ? 121.539 132.243 120.231 1.00 114.08 ? 99  PHE D CD2   1 
ATOM   4014 C CE1   . PHE B 2 99  ? 123.303 131.953 118.267 1.00 114.08 ? 99  PHE D CE1   1 
ATOM   4015 C CE2   . PHE B 2 99  ? 122.433 133.205 119.971 1.00 114.08 ? 99  PHE D CE2   1 
ATOM   4016 C CZ    . PHE B 2 99  ? 123.313 133.058 119.000 1.00 114.08 ? 99  PHE D CZ    1 
ATOM   4017 N N     . ALA B 2 100 ? 120.835 129.847 122.793 1.00 81.98  ? 100 ALA D N     1 
ATOM   4018 C CA    . ALA B 2 100 ? 121.307 130.504 123.985 1.00 81.98  ? 100 ALA D CA    1 
ATOM   4019 C C     . ALA B 2 100 ? 122.322 129.690 124.746 1.00 81.98  ? 100 ALA D C     1 
ATOM   4020 O O     . ALA B 2 100 ? 123.271 130.241 125.301 1.00 81.98  ? 100 ALA D O     1 
ATOM   4021 C CB    . ALA B 2 100 ? 120.157 130.790 124.904 1.00 111.79 ? 100 ALA D CB    1 
ATOM   4022 N N     . LYS B 2 101 ? 122.172 128.385 124.780 1.00 82.26  ? 101 LYS D N     1 
ATOM   4023 C CA    . LYS B 2 101 ? 123.071 127.619 125.610 1.00 82.26  ? 101 LYS D CA    1 
ATOM   4024 C C     . LYS B 2 101 ? 124.494 127.692 125.120 1.00 82.26  ? 101 LYS D C     1 
ATOM   4025 O O     . LYS B 2 101 ? 125.413 127.711 125.937 1.00 82.26  ? 101 LYS D O     1 
ATOM   4026 C CB    . LYS B 2 101 ? 122.639 126.184 125.671 1.00 123.28 ? 101 LYS D CB    1 
ATOM   4027 C CG    . LYS B 2 101 ? 121.412 125.938 126.438 1.00 123.28 ? 101 LYS D CG    1 
ATOM   4028 C CD    . LYS B 2 101 ? 121.642 126.009 127.898 1.00 123.28 ? 101 LYS D CD    1 
ATOM   4029 C CE    . LYS B 2 101 ? 120.432 125.497 128.649 1.00 123.28 ? 101 LYS D CE    1 
ATOM   4030 N NZ    . LYS B 2 101 ? 120.603 125.628 130.117 1.00 123.28 ? 101 LYS D NZ    1 
ATOM   4031 N N     . GLY B 2 102 ? 124.714 127.753 123.828 1.00 85.90  ? 102 GLY D N     1 
ATOM   4032 C CA    . GLY B 2 102 ? 126.069 127.773 123.362 1.00 85.90  ? 102 GLY D CA    1 
ATOM   4033 C C     . GLY B 2 102 ? 126.633 129.138 123.174 1.00 85.90  ? 102 GLY D C     1 
ATOM   4034 O O     . GLY B 2 102 ? 127.777 129.269 122.730 1.00 85.90  ? 102 GLY D O     1 
ATOM   4035 N N     . TYR B 2 103 ? 125.894 130.171 123.490 1.00 86.20  ? 103 TYR D N     1 
ATOM   4036 C CA    . TYR B 2 103 ? 126.374 131.511 123.254 1.00 86.20  ? 103 TYR D CA    1 
ATOM   4037 C C     . TYR B 2 103 ? 126.387 132.350 124.501 1.00 86.20  ? 103 TYR D C     1 
ATOM   4038 O O     . TYR B 2 103 ? 127.256 133.200 124.652 1.00 86.20  ? 103 TYR D O     1 
ATOM   4039 C CB    . TYR B 2 103 ? 125.567 132.232 122.186 1.00 119.31 ? 103 TYR D CB    1 
ATOM   4040 C CG    . TYR B 2 103 ? 126.280 133.428 121.656 1.00 119.31 ? 103 TYR D CG    1 
ATOM   4041 C CD1   . TYR B 2 103 ? 127.163 133.324 120.613 1.00 119.31 ? 103 TYR D CD1   1 
ATOM   4042 C CD2   . TYR B 2 103 ? 126.106 134.640 122.217 1.00 119.31 ? 103 TYR D CD2   1 
ATOM   4043 C CE1   . TYR B 2 103 ? 127.837 134.417 120.149 1.00 119.31 ? 103 TYR D CE1   1 
ATOM   4044 C CE2   . TYR B 2 103 ? 126.774 135.729 121.767 1.00 119.31 ? 103 TYR D CE2   1 
ATOM   4045 C CZ    . TYR B 2 103 ? 127.629 135.628 120.739 1.00 119.31 ? 103 TYR D CZ    1 
ATOM   4046 O OH    . TYR B 2 103 ? 128.290 136.768 120.314 1.00 119.31 ? 103 TYR D OH    1 
ATOM   4047 N N     . TYR B 2 104 ? 125.442 132.155 125.391 1.00 86.49  ? 104 TYR D N     1 
ATOM   4048 C CA    . TYR B 2 104 ? 125.379 132.967 126.585 1.00 86.49  ? 104 TYR D CA    1 
ATOM   4049 C C     . TYR B 2 104 ? 125.578 132.207 127.881 1.00 86.49  ? 104 TYR D C     1 
ATOM   4050 O O     . TYR B 2 104 ? 126.300 132.685 128.751 1.00 86.49  ? 104 TYR D O     1 
ATOM   4051 C CB    . TYR B 2 104 ? 124.059 133.656 126.673 1.00 119.71 ? 104 TYR D CB    1 
ATOM   4052 C CG    . TYR B 2 104 ? 123.759 134.541 125.575 1.00 119.71 ? 104 TYR D CG    1 
ATOM   4053 C CD1   . TYR B 2 104 ? 124.115 135.852 125.599 1.00 119.71 ? 104 TYR D CD1   1 
ATOM   4054 C CD2   . TYR B 2 104 ? 123.077 134.076 124.536 1.00 119.71 ? 104 TYR D CD2   1 
ATOM   4055 C CE1   . TYR B 2 104 ? 123.797 136.666 124.582 1.00 119.71 ? 104 TYR D CE1   1 
ATOM   4056 C CE2   . TYR B 2 104 ? 122.754 134.865 123.518 1.00 119.71 ? 104 TYR D CE2   1 
ATOM   4057 C CZ    . TYR B 2 104 ? 123.120 136.170 123.536 1.00 119.71 ? 104 TYR D CZ    1 
ATOM   4058 O OH    . TYR B 2 104 ? 122.783 136.958 122.482 1.00 119.71 ? 104 TYR D OH    1 
ATOM   4059 N N     . SER B 2 105 ? 124.940 131.062 128.075 1.00 87.12  ? 105 SER D N     1 
ATOM   4060 C CA    . SER B 2 105 ? 124.944 130.507 129.419 1.00 87.12  ? 105 SER D CA    1 
ATOM   4061 C C     . SER B 2 105 ? 125.792 129.271 129.703 1.00 87.12  ? 105 SER D C     1 
ATOM   4062 O O     . SER B 2 105 ? 126.218 129.111 130.837 1.00 87.12  ? 105 SER D O     1 
ATOM   4063 C CB    . SER B 2 105 ? 123.521 130.189 129.828 1.00 117.34 ? 105 SER D CB    1 
ATOM   4064 O OG    . SER B 2 105 ? 122.965 129.222 128.975 1.00 117.34 ? 105 SER D OG    1 
ATOM   4065 N N     . TYR B 2 106 ? 125.999 128.361 128.768 1.00 84.51  ? 106 TYR D N     1 
ATOM   4066 C CA    . TYR B 2 106 ? 126.751 127.166 129.103 1.00 84.51  ? 106 TYR D CA    1 
ATOM   4067 C C     . TYR B 2 106 ? 128.035 127.133 128.332 1.00 84.51  ? 106 TYR D C     1 
ATOM   4068 O O     . TYR B 2 106 ? 129.105 127.028 128.923 1.00 84.51  ? 106 TYR D O     1 
ATOM   4069 C CB    . TYR B 2 106 ? 125.952 125.876 128.847 1.00 116.97 ? 106 TYR D CB    1 
ATOM   4070 C CG    . TYR B 2 106 ? 126.653 124.589 129.261 1.00 116.97 ? 106 TYR D CG    1 
ATOM   4071 C CD1   . TYR B 2 106 ? 126.947 124.337 130.552 1.00 116.97 ? 106 TYR D CD1   1 
ATOM   4072 C CD2   . TYR B 2 106 ? 126.989 123.640 128.357 1.00 116.97 ? 106 TYR D CD2   1 
ATOM   4073 C CE1   . TYR B 2 106 ? 127.565 123.199 130.927 1.00 116.97 ? 106 TYR D CE1   1 
ATOM   4074 C CE2   . TYR B 2 106 ? 127.612 122.491 128.739 1.00 116.97 ? 106 TYR D CE2   1 
ATOM   4075 C CZ    . TYR B 2 106 ? 127.900 122.278 130.027 1.00 116.97 ? 106 TYR D CZ    1 
ATOM   4076 O OH    . TYR B 2 106 ? 128.532 121.124 130.438 1.00 116.97 ? 106 TYR D OH    1 
ATOM   4077 N N     . GLY B 2 107 ? 127.959 127.305 127.034 1.00 82.88  ? 107 GLY D N     1 
ATOM   4078 C CA    . GLY B 2 107 ? 129.116 127.158 126.197 1.00 82.88  ? 107 GLY D CA    1 
ATOM   4079 C C     . GLY B 2 107 ? 130.167 128.187 126.475 1.00 82.88  ? 107 GLY D C     1 
ATOM   4080 O O     . GLY B 2 107 ? 131.337 127.991 126.135 1.00 82.88  ? 107 GLY D O     1 
ATOM   4081 N N     . THR B 2 108 ? 129.795 129.245 127.145 1.00 84.23  ? 108 THR D N     1 
ATOM   4082 C CA    . THR B 2 108 ? 130.720 130.299 127.418 1.00 84.23  ? 108 THR D CA    1 
ATOM   4083 C C     . THR B 2 108 ? 131.737 129.890 128.449 1.00 84.23  ? 108 THR D C     1 
ATOM   4084 O O     . THR B 2 108 ? 132.852 130.412 128.446 1.00 84.23  ? 108 THR D O     1 
ATOM   4085 C CB    . THR B 2 108 ? 129.965 131.499 127.891 1.00 117.91 ? 108 THR D CB    1 
ATOM   4086 O OG1   . THR B 2 108 ? 129.227 131.139 129.063 1.00 117.91 ? 108 THR D OG1   1 
ATOM   4087 C CG2   . THR B 2 108 ? 129.001 131.898 126.845 1.00 117.91 ? 108 THR D CG2   1 
ATOM   4088 N N     . ARG B 2 109 ? 131.430 128.908 129.273 1.00 83.82  ? 109 ARG D N     1 
ATOM   4089 C CA    . ARG B 2 109 ? 132.386 128.510 130.287 1.00 83.82  ? 109 ARG D CA    1 
ATOM   4090 C C     . ARG B 2 109 ? 133.498 127.687 129.712 1.00 83.82  ? 109 ARG D C     1 
ATOM   4091 O O     . ARG B 2 109 ? 134.468 127.400 130.404 1.00 83.82  ? 109 ARG D O     1 
ATOM   4092 C CB    . ARG B 2 109 ? 131.712 127.732 131.408 1.00 123.06 ? 109 ARG D CB    1 
ATOM   4093 C CG    . ARG B 2 109 ? 131.350 126.335 131.114 1.00 123.06 ? 109 ARG D CG    1 
ATOM   4094 C CD    . ARG B 2 109 ? 130.492 125.803 132.211 1.00 123.06 ? 109 ARG D CD    1 
ATOM   4095 N NE    . ARG B 2 109 ? 129.222 126.513 132.224 1.00 123.06 ? 109 ARG D NE    1 
ATOM   4096 C CZ    . ARG B 2 109 ? 128.339 126.480 133.213 1.00 123.06 ? 109 ARG D CZ    1 
ATOM   4097 N NH1   . ARG B 2 109 ? 128.559 125.771 134.301 1.00 123.06 ? 109 ARG D NH1   1 
ATOM   4098 N NH2   . ARG B 2 109 ? 127.210 127.184 133.107 1.00 123.06 ? 109 ARG D NH2   1 
ATOM   4099 N N     . PHE B 2 110 ? 133.378 127.298 128.469 1.00 83.66  ? 110 PHE D N     1 
ATOM   4100 C CA    . PHE B 2 110 ? 134.398 126.535 127.813 1.00 83.66  ? 110 PHE D CA    1 
ATOM   4101 C C     . PHE B 2 110 ? 135.276 127.405 126.955 1.00 83.66  ? 110 PHE D C     1 
ATOM   4102 O O     . PHE B 2 110 ? 136.206 126.896 126.334 1.00 83.66  ? 110 PHE D O     1 
ATOM   4103 C CB    . PHE B 2 110 ? 133.787 125.466 126.946 1.00 116.69 ? 110 PHE D CB    1 
ATOM   4104 C CG    . PHE B 2 110 ? 133.048 124.473 127.671 1.00 116.69 ? 110 PHE D CG    1 
ATOM   4105 C CD1   . PHE B 2 110 ? 131.763 124.665 127.938 1.00 116.69 ? 110 PHE D CD1   1 
ATOM   4106 C CD2   . PHE B 2 110 ? 133.628 123.342 128.078 1.00 116.69 ? 110 PHE D CD2   1 
ATOM   4107 C CE1   . PHE B 2 110 ? 131.055 123.748 128.613 1.00 116.69 ? 110 PHE D CE1   1 
ATOM   4108 C CE2   . PHE B 2 110 ? 132.927 122.424 128.735 1.00 116.69 ? 110 PHE D CE2   1 
ATOM   4109 C CZ    . PHE B 2 110 ? 131.644 122.625 129.007 1.00 116.69 ? 110 PHE D CZ    1 
ATOM   4110 N N     . MET B 2 111 ? 135.041 128.702 126.893 1.00 90.55  ? 111 MET D N     1 
ATOM   4111 C CA    . MET B 2 111 ? 135.826 129.435 125.929 1.00 90.55  ? 111 MET D CA    1 
ATOM   4112 C C     . MET B 2 111 ? 137.272 129.511 126.322 1.00 90.55  ? 111 MET D C     1 
ATOM   4113 O O     . MET B 2 111 ? 138.126 129.601 125.446 1.00 90.55  ? 111 MET D O     1 
ATOM   4114 C CB    . MET B 2 111 ? 135.268 130.803 125.671 1.00 130.04 ? 111 MET D CB    1 
ATOM   4115 C CG    . MET B 2 111 ? 134.021 130.777 124.870 1.00 130.04 ? 111 MET D CG    1 
ATOM   4116 S SD    . MET B 2 111 ? 134.149 129.842 123.379 1.00 130.04 ? 111 MET D SD    1 
ATOM   4117 C CE    . MET B 2 111 ? 135.375 130.740 122.464 1.00 130.04 ? 111 MET D CE    1 
ATOM   4118 N N     . GLU B 2 112 ? 137.599 129.438 127.593 1.00 92.72  ? 112 GLU D N     1 
ATOM   4119 C CA    . GLU B 2 112 ? 139.008 129.433 127.928 1.00 92.72  ? 112 GLU D CA    1 
ATOM   4120 C C     . GLU B 2 112 ? 139.662 128.187 127.386 1.00 92.72  ? 112 GLU D C     1 
ATOM   4121 O O     . GLU B 2 112 ? 140.728 128.247 126.769 1.00 92.72  ? 112 GLU D O     1 
ATOM   4122 C CB    . GLU B 2 112 ? 139.212 129.505 129.418 1.00 124.54 ? 112 GLU D CB    1 
ATOM   4123 C CG    . GLU B 2 112 ? 140.665 129.552 129.806 1.00 124.54 ? 112 GLU D CG    1 
ATOM   4124 C CD    . GLU B 2 112 ? 140.853 129.672 131.287 1.00 124.54 ? 112 GLU D CD    1 
ATOM   4125 O OE1   . GLU B 2 112 ? 139.852 129.696 132.003 1.00 124.54 ? 112 GLU D OE1   1 
ATOM   4126 O OE2   . GLU B 2 112 ? 141.996 129.742 131.736 1.00 124.54 ? 112 GLU D OE2   1 
ATOM   4127 N N     . GLU B 2 113 ? 139.012 127.053 127.570 1.00 92.09  ? 113 GLU D N     1 
ATOM   4128 C CA    . GLU B 2 113 ? 139.544 125.790 127.099 1.00 92.09  ? 113 GLU D CA    1 
ATOM   4129 C C     . GLU B 2 113 ? 139.636 125.748 125.586 1.00 92.09  ? 113 GLU D C     1 
ATOM   4130 O O     . GLU B 2 113 ? 140.619 125.240 125.034 1.00 92.09  ? 113 GLU D O     1 
ATOM   4131 C CB    . GLU B 2 113 ? 138.669 124.654 127.582 1.00 123.69 ? 113 GLU D CB    1 
ATOM   4132 C CG    . GLU B 2 113 ? 139.142 123.321 127.142 1.00 123.69 ? 113 GLU D CG    1 
ATOM   4133 C CD    . GLU B 2 113 ? 138.332 122.187 127.669 1.00 123.69 ? 113 GLU D CD    1 
ATOM   4134 O OE1   . GLU B 2 113 ? 137.442 122.403 128.486 1.00 123.69 ? 113 GLU D OE1   1 
ATOM   4135 O OE2   . GLU B 2 113 ? 138.587 121.061 127.249 1.00 123.69 ? 113 GLU D OE2   1 
ATOM   4136 N N     . ILE B 2 114 ? 138.614 126.246 124.899 1.00 91.44  ? 114 ILE D N     1 
ATOM   4137 C CA    . ILE B 2 114 ? 138.600 126.198 123.447 1.00 91.44  ? 114 ILE D CA    1 
ATOM   4138 C C     . ILE B 2 114 ? 139.685 127.081 122.888 1.00 91.44  ? 114 ILE D C     1 
ATOM   4139 O O     . ILE B 2 114 ? 140.422 126.667 121.990 1.00 91.44  ? 114 ILE D O     1 
ATOM   4140 C CB    . ILE B 2 114 ? 137.233 126.590 122.865 1.00 135.30 ? 114 ILE D CB    1 
ATOM   4141 C CG1   . ILE B 2 114 ? 136.205 125.564 123.223 1.00 135.30 ? 114 ILE D CG1   1 
ATOM   4142 C CG2   . ILE B 2 114 ? 137.312 126.691 121.376 1.00 135.30 ? 114 ILE D CG2   1 
ATOM   4143 C CD1   . ILE B 2 114 ? 134.792 125.993 123.016 1.00 135.30 ? 114 ILE D CD1   1 
ATOM   4144 N N     . MET B 2 115 ? 139.819 128.296 123.399 1.00 93.23  ? 115 MET D N     1 
ATOM   4145 C CA    . MET B 2 115 ? 140.836 129.160 122.833 1.00 93.23  ? 115 MET D CA    1 
ATOM   4146 C C     . MET B 2 115 ? 142.223 128.694 123.206 1.00 93.23  ? 115 MET D C     1 
ATOM   4147 O O     . MET B 2 115 ? 143.169 128.917 122.446 1.00 93.23  ? 115 MET D O     1 
ATOM   4148 C CB    . MET B 2 115 ? 140.632 130.596 123.251 1.00 133.89 ? 115 MET D CB    1 
ATOM   4149 C CG    . MET B 2 115 ? 139.415 131.232 122.642 1.00 133.89 ? 115 MET D CG    1 
ATOM   4150 S SD    . MET B 2 115 ? 139.321 131.093 120.857 1.00 133.89 ? 115 MET D SD    1 
ATOM   4151 C CE    . MET B 2 115 ? 140.715 132.067 120.300 1.00 133.89 ? 115 MET D CE    1 
ATOM   4152 N N     . ASP B 2 116 ? 142.378 128.012 124.326 1.00 90.72  ? 116 ASP D N     1 
ATOM   4153 C CA    . ASP B 2 116 ? 143.685 127.486 124.647 1.00 90.72  ? 116 ASP D CA    1 
ATOM   4154 C C     . ASP B 2 116 ? 144.053 126.387 123.678 1.00 90.72  ? 116 ASP D C     1 
ATOM   4155 O O     . ASP B 2 116 ? 145.180 126.350 123.170 1.00 90.72  ? 116 ASP D O     1 
ATOM   4156 C CB    . ASP B 2 116 ? 143.703 126.980 126.068 1.00 116.64 ? 116 ASP D CB    1 
ATOM   4157 C CG    . ASP B 2 116 ? 145.070 126.552 126.528 1.00 116.64 ? 116 ASP D CG    1 
ATOM   4158 O OD1   . ASP B 2 116 ? 145.938 127.405 126.709 1.00 116.64 ? 116 ASP D OD1   1 
ATOM   4159 O OD2   . ASP B 2 116 ? 145.287 125.348 126.709 1.00 116.64 ? 116 ASP D OD2   1 
ATOM   4160 N N     . LYS B 2 117 ? 143.110 125.511 123.360 1.00 89.84  ? 117 LYS D N     1 
ATOM   4161 C CA    . LYS B 2 117 ? 143.446 124.465 122.409 1.00 89.84  ? 117 LYS D CA    1 
ATOM   4162 C C     . LYS B 2 117 ? 143.718 125.038 121.030 1.00 89.84  ? 117 LYS D C     1 
ATOM   4163 O O     . LYS B 2 117 ? 144.597 124.548 120.304 1.00 89.84  ? 117 LYS D O     1 
ATOM   4164 C CB    . LYS B 2 117 ? 142.352 123.430 122.351 1.00 134.64 ? 117 LYS D CB    1 
ATOM   4165 C CG    . LYS B 2 117 ? 142.294 122.621 123.577 1.00 134.64 ? 117 LYS D CG    1 
ATOM   4166 C CD    . LYS B 2 117 ? 141.283 121.576 123.470 1.00 134.64 ? 117 LYS D CD    1 
ATOM   4167 C CE    . LYS B 2 117 ? 141.074 120.866 124.788 1.00 134.64 ? 117 LYS D CE    1 
ATOM   4168 N NZ    . LYS B 2 117 ? 142.305 120.260 125.323 1.00 134.64 ? 117 LYS D NZ    1 
ATOM   4169 N N     . ILE B 2 118 ? 142.977 126.072 120.641 1.00 90.96  ? 118 ILE D N     1 
ATOM   4170 C CA    . ILE B 2 118 ? 143.225 126.643 119.341 1.00 90.96  ? 118 ILE D CA    1 
ATOM   4171 C C     . ILE B 2 118 ? 144.597 127.212 119.292 1.00 90.96  ? 118 ILE D C     1 
ATOM   4172 O O     . ILE B 2 118 ? 145.319 126.972 118.335 1.00 90.96  ? 118 ILE D O     1 
ATOM   4173 C CB    . ILE B 2 118 ? 142.196 127.690 118.961 1.00 134.59 ? 118 ILE D CB    1 
ATOM   4174 C CG1   . ILE B 2 118 ? 140.887 127.008 118.737 1.00 134.59 ? 118 ILE D CG1   1 
ATOM   4175 C CG2   . ILE B 2 118 ? 142.649 128.389 117.711 1.00 134.59 ? 118 ILE D CG2   1 
ATOM   4176 C CD1   . ILE B 2 118 ? 139.729 127.924 118.705 1.00 134.59 ? 118 ILE D CD1   1 
ATOM   4177 N N     . GLN B 2 119 ? 145.006 127.949 120.306 1.00 91.69  ? 119 GLN D N     1 
ATOM   4178 C CA    . GLN B 2 119 ? 146.347 128.489 120.218 1.00 91.69  ? 119 GLN D CA    1 
ATOM   4179 C C     . GLN B 2 119 ? 147.353 127.384 120.120 1.00 91.69  ? 119 GLN D C     1 
ATOM   4180 O O     . GLN B 2 119 ? 148.315 127.494 119.358 1.00 91.69  ? 119 GLN D O     1 
ATOM   4181 C CB    . GLN B 2 119 ? 146.722 129.368 121.367 1.00 128.08 ? 119 GLN D CB    1 
ATOM   4182 C CG    . GLN B 2 119 ? 148.064 129.980 121.125 1.00 128.08 ? 119 GLN D CG    1 
ATOM   4183 C CD    . GLN B 2 119 ? 148.491 130.898 122.209 1.00 128.08 ? 119 GLN D CD    1 
ATOM   4184 O OE1   . GLN B 2 119 ? 147.728 131.748 122.686 1.00 128.08 ? 119 GLN D OE1   1 
ATOM   4185 N NE2   . GLN B 2 119 ? 149.739 130.743 122.623 1.00 128.08 ? 119 GLN D NE2   1 
ATOM   4186 N N     . LYS B 2 120 ? 147.147 126.290 120.832 1.00 91.90  ? 120 LYS D N     1 
ATOM   4187 C CA    . LYS B 2 120 ? 148.139 125.230 120.705 1.00 91.90  ? 120 LYS D CA    1 
ATOM   4188 C C     . LYS B 2 120 ? 148.255 124.737 119.278 1.00 91.90  ? 120 LYS D C     1 
ATOM   4189 O O     . LYS B 2 120 ? 149.348 124.349 118.864 1.00 91.90  ? 120 LYS D O     1 
ATOM   4190 C CB    . LYS B 2 120 ? 147.842 124.085 121.647 1.00 137.73 ? 120 LYS D CB    1 
ATOM   4191 C CG    . LYS B 2 120 ? 148.154 124.435 123.073 1.00 137.73 ? 120 LYS D CG    1 
ATOM   4192 C CD    . LYS B 2 120 ? 147.929 123.287 124.026 1.00 137.73 ? 120 LYS D CD    1 
ATOM   4193 C CE    . LYS B 2 120 ? 148.403 123.641 125.437 1.00 137.73 ? 120 LYS D CE    1 
ATOM   4194 N NZ    . LYS B 2 120 ? 147.582 124.719 126.064 1.00 137.73 ? 120 LYS D NZ    1 
ATOM   4195 N N     . GLU B 2 121 ? 147.169 124.742 118.502 1.00 91.38  ? 121 GLU D N     1 
ATOM   4196 C CA    . GLU B 2 121 ? 147.309 124.360 117.096 1.00 91.38  ? 121 GLU D CA    1 
ATOM   4197 C C     . GLU B 2 121 ? 148.020 125.448 116.302 1.00 91.38  ? 121 GLU D C     1 
ATOM   4198 O O     . GLU B 2 121 ? 148.866 125.167 115.449 1.00 91.38  ? 121 GLU D O     1 
ATOM   4199 C CB    . GLU B 2 121 ? 145.955 124.064 116.484 1.00 122.74 ? 121 GLU D CB    1 
ATOM   4200 C CG    . GLU B 2 121 ? 145.292 122.897 117.070 1.00 122.74 ? 121 GLU D CG    1 
ATOM   4201 C CD    . GLU B 2 121 ? 146.139 121.691 116.965 1.00 122.74 ? 121 GLU D CD    1 
ATOM   4202 O OE1   . GLU B 2 121 ? 146.533 121.343 115.854 1.00 122.74 ? 121 GLU D OE1   1 
ATOM   4203 O OE2   . GLU B 2 121 ? 146.456 121.111 117.999 1.00 122.74 ? 121 GLU D OE2   1 
ATOM   4204 N N     . VAL B 2 122 ? 147.719 126.697 116.602 1.00 89.56  ? 122 VAL D N     1 
ATOM   4205 C CA    . VAL B 2 122 ? 148.309 127.812 115.888 1.00 89.56  ? 122 VAL D CA    1 
ATOM   4206 C C     . VAL B 2 122 ? 149.798 127.828 116.090 1.00 89.56  ? 122 VAL D C     1 
ATOM   4207 O O     . VAL B 2 122 ? 150.557 128.110 115.168 1.00 89.56  ? 122 VAL D O     1 
ATOM   4208 C CB    . VAL B 2 122 ? 147.712 129.129 116.377 1.00 130.23 ? 122 VAL D CB    1 
ATOM   4209 C CG1   . VAL B 2 122 ? 148.465 130.301 115.784 1.00 130.23 ? 122 VAL D CG1   1 
ATOM   4210 C CG2   . VAL B 2 122 ? 146.240 129.204 116.049 1.00 130.23 ? 122 VAL D CG2   1 
ATOM   4211 N N     . ASP B 2 123 ? 150.240 127.545 117.297 1.00 91.39  ? 123 ASP D N     1 
ATOM   4212 C CA    . ASP B 2 123 ? 151.642 127.608 117.654 1.00 91.39  ? 123 ASP D CA    1 
ATOM   4213 C C     . ASP B 2 123 ? 152.489 126.564 116.972 1.00 91.39  ? 123 ASP D C     1 
ATOM   4214 O O     . ASP B 2 123 ? 153.714 126.650 117.034 1.00 91.39  ? 123 ASP D O     1 
ATOM   4215 C CB    . ASP B 2 123 ? 151.819 127.449 119.160 1.00 117.50 ? 123 ASP D CB    1 
ATOM   4216 C CG    . ASP B 2 123 ? 151.438 128.709 119.963 1.00 117.50 ? 123 ASP D CG    1 
ATOM   4217 O OD1   . ASP B 2 123 ? 151.321 129.787 119.375 1.00 117.50 ? 123 ASP D OD1   1 
ATOM   4218 O OD2   . ASP B 2 123 ? 151.283 128.613 121.191 1.00 117.50 ? 123 ASP D OD2   1 
ATOM   4219 N N     . GLN B 2 124 ? 151.901 125.567 116.350 1.00 93.98  ? 124 GLN D N     1 
ATOM   4220 C CA    . GLN B 2 124 ? 152.696 124.562 115.668 1.00 93.98  ? 124 GLN D CA    1 
ATOM   4221 C C     . GLN B 2 124 ? 152.938 124.901 114.222 1.00 93.98  ? 124 GLN D C     1 
ATOM   4222 O O     . GLN B 2 124 ? 153.638 124.156 113.541 1.00 93.98  ? 124 GLN D O     1 
ATOM   4223 C CB    . GLN B 2 124 ? 152.033 123.203 115.746 1.00 131.28 ? 124 GLN D CB    1 
ATOM   4224 C CG    . GLN B 2 124 ? 151.970 122.689 117.119 1.00 131.28 ? 124 GLN D CG    1 
ATOM   4225 C CD    . GLN B 2 124 ? 151.176 121.453 117.203 1.00 131.28 ? 124 GLN D CD    1 
ATOM   4226 O OE1   . GLN B 2 124 ? 151.600 120.396 116.747 1.00 131.28 ? 124 GLN D OE1   1 
ATOM   4227 N NE2   . GLN B 2 124 ? 149.987 121.566 117.785 1.00 131.28 ? 124 GLN D NE2   1 
ATOM   4228 N N     . THR B 2 125 ? 152.378 125.999 113.726 1.00 91.77  ? 125 THR D N     1 
ATOM   4229 C CA    . THR B 2 125 ? 152.512 126.300 112.317 1.00 91.77  ? 125 THR D CA    1 
ATOM   4230 C C     . THR B 2 125 ? 153.057 127.678 112.009 1.00 91.77  ? 125 THR D C     1 
ATOM   4231 O O     . THR B 2 125 ? 152.611 128.683 112.563 1.00 91.77  ? 125 THR D O     1 
ATOM   4232 C CB    . THR B 2 125 ? 151.194 126.106 111.612 1.00 128.46 ? 125 THR D CB    1 
ATOM   4233 O OG1   . THR B 2 125 ? 151.332 126.563 110.267 1.00 128.46 ? 125 THR D OG1   1 
ATOM   4234 C CG2   . THR B 2 125 ? 150.088 126.831 112.281 1.00 128.46 ? 125 THR D CG2   1 
ATOM   4235 N N     . GLU B 2 126 ? 153.999 127.705 111.082 1.00 89.72  ? 126 GLU D N     1 
ATOM   4236 C CA    . GLU B 2 126 ? 154.653 128.929 110.657 1.00 89.72  ? 126 GLU D CA    1 
ATOM   4237 C C     . GLU B 2 126 ? 153.749 129.863 109.871 1.00 89.72  ? 126 GLU D C     1 
ATOM   4238 O O     . GLU B 2 126 ? 153.901 131.086 109.968 1.00 89.72  ? 126 GLU D O     1 
ATOM   4239 C CB    . GLU B 2 126 ? 155.848 128.600 109.805 1.00 120.51 ? 126 GLU D CB    1 
ATOM   4240 C CG    . GLU B 2 126 ? 156.969 127.927 110.552 1.00 120.51 ? 126 GLU D CG    1 
ATOM   4241 C CD    . GLU B 2 126 ? 156.743 126.455 110.739 1.00 120.51 ? 126 GLU D CD    1 
ATOM   4242 O OE1   . GLU B 2 126 ? 155.716 125.950 110.277 1.00 120.51 ? 126 GLU D OE1   1 
ATOM   4243 O OE2   . GLU B 2 126 ? 157.593 125.803 111.343 1.00 120.51 ? 126 GLU D OE2   1 
ATOM   4244 N N     . HIS B 2 127 ? 152.846 129.341 109.051 1.00 88.20  ? 127 HIS D N     1 
ATOM   4245 C CA    . HIS B 2 127 ? 152.066 130.234 108.183 1.00 88.20  ? 127 HIS D CA    1 
ATOM   4246 C C     . HIS B 2 127 ? 150.582 129.936 108.111 1.00 88.20  ? 127 HIS D C     1 
ATOM   4247 O O     . HIS B 2 127 ? 150.172 129.243 107.190 1.00 88.20  ? 127 HIS D O     1 
ATOM   4248 C CB    . HIS B 2 127 ? 152.598 130.172 106.784 1.00 119.93 ? 127 HIS D CB    1 
ATOM   4249 C CG    . HIS B 2 127 ? 154.024 130.495 106.670 1.00 119.93 ? 127 HIS D CG    1 
ATOM   4250 N ND1   . HIS B 2 127 ? 154.506 131.774 106.772 1.00 119.93 ? 127 HIS D ND1   1 
ATOM   4251 C CD2   . HIS B 2 127 ? 155.083 129.707 106.442 1.00 119.93 ? 127 HIS D CD2   1 
ATOM   4252 C CE1   . HIS B 2 127 ? 155.813 131.756 106.620 1.00 119.93 ? 127 HIS D CE1   1 
ATOM   4253 N NE2   . HIS B 2 127 ? 156.187 130.513 106.417 1.00 119.93 ? 127 HIS D NE2   1 
ATOM   4254 N N     . LEU B 2 128 ? 149.771 130.455 109.020 1.00 86.48  ? 128 LEU D N     1 
ATOM   4255 C CA    . LEU B 2 128 ? 148.358 130.176 108.858 1.00 86.48  ? 128 LEU D CA    1 
ATOM   4256 C C     . LEU B 2 128 ? 147.795 130.980 107.729 1.00 86.48  ? 128 LEU D C     1 
ATOM   4257 O O     . LEU B 2 128 ? 148.148 132.128 107.511 1.00 86.48  ? 128 LEU D O     1 
ATOM   4258 C CB    . LEU B 2 128 ? 147.523 130.491 110.054 1.00 127.96 ? 128 LEU D CB    1 
ATOM   4259 C CG    . LEU B 2 128 ? 147.628 129.582 111.195 1.00 127.96 ? 128 LEU D CG    1 
ATOM   4260 C CD1   . LEU B 2 128 ? 146.864 130.162 112.305 1.00 127.96 ? 128 LEU D CD1   1 
ATOM   4261 C CD2   . LEU B 2 128 ? 147.039 128.257 110.853 1.00 127.96 ? 128 LEU D CD2   1 
ATOM   4262 N N     . GLN B 2 129 ? 146.919 130.343 107.010 1.00 88.52  ? 129 GLN D N     1 
ATOM   4263 C CA    . GLN B 2 129 ? 146.124 130.935 105.986 1.00 88.52  ? 129 GLN D CA    1 
ATOM   4264 C C     . GLN B 2 129 ? 144.811 131.315 106.562 1.00 88.52  ? 129 GLN D C     1 
ATOM   4265 O O     . GLN B 2 129 ? 144.281 132.381 106.258 1.00 88.52  ? 129 GLN D O     1 
ATOM   4266 C CB    . GLN B 2 129 ? 145.913 129.909 104.896 1.00 123.65 ? 129 GLN D CB    1 
ATOM   4267 C CG    . GLN B 2 129 ? 145.398 130.427 103.687 1.00 123.65 ? 129 GLN D CG    1 
ATOM   4268 C CD    . GLN B 2 129 ? 145.153 129.346 102.715 1.00 123.65 ? 129 GLN D CD    1 
ATOM   4269 O OE1   . GLN B 2 129 ? 144.020 128.958 102.512 1.00 123.65 ? 129 GLN D OE1   1 
ATOM   4270 N NE2   . GLN B 2 129 ? 146.197 128.846 102.093 1.00 123.65 ? 129 GLN D NE2   1 
ATOM   4271 N N     . GLY B 2 130 ? 144.282 130.447 107.408 1.00 86.00  ? 130 GLY D N     1 
ATOM   4272 C CA    . GLY B 2 130 ? 142.977 130.698 107.947 1.00 86.00  ? 130 GLY D CA    1 
ATOM   4273 C C     . GLY B 2 130 ? 142.414 129.559 108.755 1.00 86.00  ? 130 GLY D C     1 
ATOM   4274 O O     . GLY B 2 130 ? 143.082 128.565 109.039 1.00 86.00  ? 130 GLY D O     1 
ATOM   4275 N N     . PHE B 2 131 ? 141.161 129.746 109.133 1.00 86.32  ? 131 PHE D N     1 
ATOM   4276 C CA    . PHE B 2 131 ? 140.383 128.795 109.909 1.00 86.32  ? 131 PHE D CA    1 
ATOM   4277 C C     . PHE B 2 131 ? 139.117 128.413 109.184 1.00 86.32  ? 131 PHE D C     1 
ATOM   4278 O O     . PHE B 2 131 ? 138.482 129.249 108.555 1.00 86.32  ? 131 PHE D O     1 
ATOM   4279 C CB    . PHE B 2 131 ? 139.931 129.378 111.194 1.00 120.40 ? 131 PHE D CB    1 
ATOM   4280 C CG    . PHE B 2 131 ? 140.951 129.545 112.190 1.00 120.40 ? 131 PHE D CG    1 
ATOM   4281 C CD1   . PHE B 2 131 ? 141.717 130.626 112.239 1.00 120.40 ? 131 PHE D CD1   1 
ATOM   4282 C CD2   . PHE B 2 131 ? 141.095 128.614 113.131 1.00 120.40 ? 131 PHE D CD2   1 
ATOM   4283 C CE1   . PHE B 2 131 ? 142.639 130.757 113.193 1.00 120.40 ? 131 PHE D CE1   1 
ATOM   4284 C CE2   . PHE B 2 131 ? 141.997 128.745 114.084 1.00 120.40 ? 131 PHE D CE2   1 
ATOM   4285 C CZ    . PHE B 2 131 ? 142.779 129.827 114.117 1.00 120.40 ? 131 PHE D CZ    1 
ATOM   4286 N N     . ILE B 2 132 ? 138.728 127.168 109.301 1.00 87.90  ? 132 ILE D N     1 
ATOM   4287 C CA    . ILE B 2 132 ? 137.454 126.718 108.802 1.00 87.90  ? 132 ILE D CA    1 
ATOM   4288 C C     . ILE B 2 132 ? 136.656 126.135 109.939 1.00 87.90  ? 132 ILE D C     1 
ATOM   4289 O O     . ILE B 2 132 ? 137.141 125.266 110.666 1.00 87.90  ? 132 ILE D O     1 
ATOM   4290 C CB    . ILE B 2 132 ? 137.592 125.687 107.689 1.00 130.06 ? 132 ILE D CB    1 
ATOM   4291 C CG1   . ILE B 2 132 ? 138.318 126.309 106.508 1.00 130.06 ? 132 ILE D CG1   1 
ATOM   4292 C CG2   . ILE B 2 132 ? 136.196 125.201 107.286 1.00 130.06 ? 132 ILE D CG2   1 
ATOM   4293 C CD1   . ILE B 2 132 ? 138.677 125.353 105.375 1.00 130.06 ? 132 ILE D CD1   1 
ATOM   4294 N N     . VAL B 2 133 ? 135.444 126.619 110.120 1.00 86.65  ? 133 VAL D N     1 
ATOM   4295 C CA    . VAL B 2 133 ? 134.594 126.148 111.189 1.00 86.65  ? 133 VAL D CA    1 
ATOM   4296 C C     . VAL B 2 133 ? 133.412 125.459 110.562 1.00 86.65  ? 133 VAL D C     1 
ATOM   4297 O O     . VAL B 2 133 ? 132.636 126.082 109.838 1.00 86.65  ? 133 VAL D O     1 
ATOM   4298 C CB    . VAL B 2 133 ? 134.170 127.303 112.091 1.00 125.99 ? 133 VAL D CB    1 
ATOM   4299 C CG1   . VAL B 2 133 ? 133.269 126.811 113.199 1.00 125.99 ? 133 VAL D CG1   1 
ATOM   4300 C CG2   . VAL B 2 133 ? 135.414 127.955 112.672 1.00 125.99 ? 133 VAL D CG2   1 
ATOM   4301 N N     . VAL B 2 134 ? 133.243 124.197 110.858 1.00 86.17  ? 134 VAL D N     1 
ATOM   4302 C CA    . VAL B 2 134 ? 132.169 123.411 110.310 1.00 86.17  ? 134 VAL D CA    1 
ATOM   4303 C C     . VAL B 2 134 ? 131.088 123.218 111.336 1.00 86.17  ? 134 VAL D C     1 
ATOM   4304 O O     . VAL B 2 134 ? 131.348 122.648 112.397 1.00 86.17  ? 134 VAL D O     1 
ATOM   4305 C CB    . VAL B 2 134 ? 132.679 122.054 109.870 1.00 125.30 ? 134 VAL D CB    1 
ATOM   4306 C CG1   . VAL B 2 134 ? 131.563 121.255 109.273 1.00 125.30 ? 134 VAL D CG1   1 
ATOM   4307 C CG2   . VAL B 2 134 ? 133.823 122.232 108.905 1.00 125.30 ? 134 VAL D CG2   1 
ATOM   4308 N N     . HIS B 2 135 ? 129.867 123.644 111.047 1.00 88.72  ? 135 HIS D N     1 
ATOM   4309 C CA    . HIS B 2 135 ? 128.858 123.539 112.069 1.00 88.72  ? 135 HIS D CA    1 
ATOM   4310 C C     . HIS B 2 135 ? 127.462 123.500 111.528 1.00 88.72  ? 135 HIS D C     1 
ATOM   4311 O O     . HIS B 2 135 ? 127.189 123.951 110.423 1.00 88.72  ? 135 HIS D O     1 
ATOM   4312 C CB    . HIS B 2 135 ? 128.952 124.694 113.012 1.00 120.64 ? 135 HIS D CB    1 
ATOM   4313 C CG    . HIS B 2 135 ? 128.545 125.972 112.422 1.00 120.64 ? 135 HIS D CG    1 
ATOM   4314 N ND1   . HIS B 2 135 ? 129.301 126.639 111.513 1.00 120.64 ? 135 HIS D ND1   1 
ATOM   4315 C CD2   . HIS B 2 135 ? 127.466 126.740 112.652 1.00 120.64 ? 135 HIS D CD2   1 
ATOM   4316 C CE1   . HIS B 2 135 ? 128.701 127.760 111.183 1.00 120.64 ? 135 HIS D CE1   1 
ATOM   4317 N NE2   . HIS B 2 135 ? 127.582 127.847 111.861 1.00 120.64 ? 135 HIS D NE2   1 
ATOM   4318 N N     . SER B 2 136 ? 126.572 122.980 112.329 1.00 88.61  ? 136 SER D N     1 
ATOM   4319 C CA    . SER B 2 136 ? 125.169 122.986 111.996 1.00 88.61  ? 136 SER D CA    1 
ATOM   4320 C C     . SER B 2 136 ? 124.584 124.292 112.422 1.00 88.61  ? 136 SER D C     1 
ATOM   4321 O O     . SER B 2 136 ? 124.911 124.803 113.491 1.00 88.61  ? 136 SER D O     1 
ATOM   4322 C CB    . SER B 2 136 ? 124.443 121.893 112.741 1.00 119.35 ? 136 SER D CB    1 
ATOM   4323 O OG    . SER B 2 136 ? 123.081 121.961 112.431 1.00 119.35 ? 136 SER D OG    1 
ATOM   4324 N N     . ILE B 2 137 ? 123.709 124.842 111.621 1.00 90.60  ? 137 ILE D N     1 
ATOM   4325 C CA    . ILE B 2 137 ? 123.072 126.086 111.976 1.00 90.60  ? 137 ILE D CA    1 
ATOM   4326 C C     . ILE B 2 137 ? 121.640 125.759 112.293 1.00 90.60  ? 137 ILE D C     1 
ATOM   4327 O O     . ILE B 2 137 ? 120.975 125.078 111.520 1.00 90.60  ? 137 ILE D O     1 
ATOM   4328 C CB    . ILE B 2 137 ? 123.193 127.142 110.878 1.00 134.05 ? 137 ILE D CB    1 
ATOM   4329 C CG1   . ILE B 2 137 ? 122.552 128.376 111.378 1.00 134.05 ? 137 ILE D CG1   1 
ATOM   4330 C CG2   . ILE B 2 137 ? 122.536 126.714 109.615 1.00 134.05 ? 137 ILE D CG2   1 
ATOM   4331 C CD1   . ILE B 2 137 ? 122.862 129.619 110.588 1.00 134.05 ? 137 ILE D CD1   1 
ATOM   4332 N N     . GLY B 2 138 ? 121.165 126.183 113.436 1.00 87.52  ? 138 GLY D N     1 
ATOM   4333 C CA    . GLY B 2 138 ? 119.820 125.823 113.862 1.00 87.52  ? 138 GLY D CA    1 
ATOM   4334 C C     . GLY B 2 138 ? 119.783 124.823 114.999 1.00 87.52  ? 138 GLY D C     1 
ATOM   4335 O O     . GLY B 2 138 ? 118.756 124.664 115.658 1.00 87.52  ? 138 GLY D O     1 
ATOM   4336 N N     . ASP B 2 139 ? 120.892 124.189 115.268 1.00 87.21  ? 139 ASP D N     1 
ATOM   4337 C CA    . ASP B 2 139 ? 121.065 123.276 116.379 1.00 87.21  ? 139 ASP D CA    1 
ATOM   4338 C C     . ASP B 2 139 ? 121.890 123.976 117.435 1.00 87.21  ? 139 ASP D C     1 
ATOM   4339 O O     . ASP B 2 139 ? 123.068 124.234 117.216 1.00 87.21  ? 139 ASP D O     1 
ATOM   4340 C CB    . ASP B 2 139 ? 121.816 122.033 115.936 1.00 112.13 ? 139 ASP D CB    1 
ATOM   4341 C CG    . ASP B 2 139 ? 121.056 121.198 114.946 1.00 112.13 ? 139 ASP D CG    1 
ATOM   4342 O OD1   . ASP B 2 139 ? 119.825 121.241 114.915 1.00 112.13 ? 139 ASP D OD1   1 
ATOM   4343 O OD2   . ASP B 2 139 ? 121.717 120.465 114.206 1.00 112.13 ? 139 ASP D OD2   1 
ATOM   4344 N N     . GLY B 2 140 ? 121.299 124.258 118.575 1.00 84.66  ? 140 GLY D N     1 
ATOM   4345 C CA    . GLY B 2 140 ? 121.901 125.082 119.601 1.00 84.66  ? 140 GLY D CA    1 
ATOM   4346 C C     . GLY B 2 140 ? 123.392 124.988 119.793 1.00 84.66  ? 140 GLY D C     1 
ATOM   4347 O O     . GLY B 2 140 ? 124.072 126.003 119.767 1.00 84.66  ? 140 GLY D O     1 
ATOM   4348 N N     . THR B 2 141 ? 123.942 123.808 119.982 1.00 82.65  ? 141 THR D N     1 
ATOM   4349 C CA    . THR B 2 141 ? 125.375 123.727 120.233 1.00 82.65  ? 141 THR D CA    1 
ATOM   4350 C C     . THR B 2 141 ? 126.188 124.336 119.125 1.00 82.65  ? 141 THR D C     1 
ATOM   4351 O O     . THR B 2 141 ? 127.157 125.048 119.384 1.00 82.65  ? 141 THR D O     1 
ATOM   4352 C CB    . THR B 2 141 ? 125.798 122.308 120.398 1.00 115.69 ? 141 THR D CB    1 
ATOM   4353 O OG1   . THR B 2 141 ? 125.132 121.767 121.540 1.00 115.69 ? 141 THR D OG1   1 
ATOM   4354 C CG2   . THR B 2 141 ? 127.299 122.230 120.590 1.00 115.69 ? 141 THR D CG2   1 
ATOM   4355 N N     . GLY B 2 142 ? 125.818 124.082 117.889 1.00 85.00  ? 142 GLY D N     1 
ATOM   4356 C CA    . GLY B 2 142 ? 126.520 124.622 116.751 1.00 85.00  ? 142 GLY D CA    1 
ATOM   4357 C C     . GLY B 2 142 ? 126.161 126.063 116.522 1.00 85.00  ? 142 GLY D C     1 
ATOM   4358 O O     . GLY B 2 142 ? 127.024 126.924 116.382 1.00 85.00  ? 142 GLY D O     1 
ATOM   4359 N N     . ALA B 2 143 ? 124.872 126.330 116.556 1.00 84.58  ? 143 ALA D N     1 
ATOM   4360 C CA    . ALA B 2 143 ? 124.357 127.655 116.303 1.00 84.58  ? 143 ALA D CA    1 
ATOM   4361 C C     . ALA B 2 143 ? 124.916 128.650 117.279 1.00 84.58  ? 143 ALA D C     1 
ATOM   4362 O O     . ALA B 2 143 ? 125.179 129.794 116.933 1.00 84.58  ? 143 ALA D O     1 
ATOM   4363 C CB    . ALA B 2 143 ? 122.844 127.616 116.400 1.00 115.34 ? 143 ALA D CB    1 
ATOM   4364 N N     . GLY B 2 144 ? 125.129 128.219 118.488 1.00 85.56  ? 144 GLY D N     1 
ATOM   4365 C CA    . GLY B 2 144 ? 125.675 128.990 119.557 1.00 85.56  ? 144 GLY D CA    1 
ATOM   4366 C C     . GLY B 2 144 ? 127.175 129.035 119.547 1.00 85.56  ? 144 GLY D C     1 
ATOM   4367 O O     . GLY B 2 144 ? 127.745 130.113 119.359 1.00 85.56  ? 144 GLY D O     1 
ATOM   4368 N N     . LEU B 2 145 ? 127.851 127.911 119.726 1.00 86.37  ? 145 LEU D N     1 
ATOM   4369 C CA    . LEU B 2 145 ? 129.288 128.006 119.847 1.00 86.37  ? 145 LEU D CA    1 
ATOM   4370 C C     . LEU B 2 145 ? 129.975 128.420 118.567 1.00 86.37  ? 145 LEU D C     1 
ATOM   4371 O O     . LEU B 2 145 ? 131.000 129.089 118.631 1.00 86.37  ? 145 LEU D O     1 
ATOM   4372 C CB    . LEU B 2 145 ? 129.906 126.719 120.277 1.00 127.79 ? 145 LEU D CB    1 
ATOM   4373 C CG    . LEU B 2 145 ? 129.797 126.305 121.686 1.00 127.79 ? 145 LEU D CG    1 
ATOM   4374 C CD1   . LEU B 2 145 ? 130.303 124.925 121.750 1.00 127.79 ? 145 LEU D CD1   1 
ATOM   4375 C CD2   . LEU B 2 145 ? 130.641 127.185 122.533 1.00 127.79 ? 145 LEU D CD2   1 
ATOM   4376 N N     . ALA B 2 146 ? 129.521 127.992 117.406 1.00 86.05  ? 146 ALA D N     1 
ATOM   4377 C CA    . ALA B 2 146 ? 130.338 128.326 116.258 1.00 86.05  ? 146 ALA D CA    1 
ATOM   4378 C C     . ALA B 2 146 ? 130.604 129.809 116.162 1.00 86.05  ? 146 ALA D C     1 
ATOM   4379 O O     . ALA B 2 146 ? 131.780 130.176 116.090 1.00 86.05  ? 146 ALA D O     1 
ATOM   4380 C CB    . ALA B 2 146 ? 129.721 127.760 114.987 1.00 117.34 ? 146 ALA D CB    1 
ATOM   4381 N N     . PRO B 2 147 ? 129.622 130.701 116.201 1.00 85.85  ? 147 PRO D N     1 
ATOM   4382 C CA    . PRO B 2 147 ? 129.927 132.112 116.180 1.00 85.85  ? 147 PRO D CA    1 
ATOM   4383 C C     . PRO B 2 147 ? 130.592 132.600 117.428 1.00 85.85  ? 147 PRO D C     1 
ATOM   4384 O O     . PRO B 2 147 ? 131.368 133.557 117.354 1.00 85.85  ? 147 PRO D O     1 
ATOM   4385 C CB    . PRO B 2 147 ? 128.568 132.750 115.962 1.00 267.77 ? 147 PRO D CB    1 
ATOM   4386 C CG    . PRO B 2 147 ? 127.625 131.779 116.403 1.00 267.77 ? 147 PRO D CG    1 
ATOM   4387 C CD    . PRO B 2 147 ? 128.192 130.471 116.065 1.00 267.77 ? 147 PRO D CD    1 
ATOM   4388 N N     . LEU B 2 148 ? 130.426 131.948 118.559 1.00 87.11  ? 148 LEU D N     1 
ATOM   4389 C CA    . LEU B 2 148 ? 131.157 132.422 119.729 1.00 87.11  ? 148 LEU D CA    1 
ATOM   4390 C C     . LEU B 2 148 ? 132.647 132.209 119.543 1.00 87.11  ? 148 LEU D C     1 
ATOM   4391 O O     . LEU B 2 148 ? 133.467 133.087 119.862 1.00 87.11  ? 148 LEU D O     1 
ATOM   4392 C CB    . LEU B 2 148 ? 130.699 131.685 120.969 1.00 128.89 ? 148 LEU D CB    1 
ATOM   4393 C CG    . LEU B 2 148 ? 131.250 132.141 122.299 1.00 128.89 ? 148 LEU D CG    1 
ATOM   4394 C CD1   . LEU B 2 148 ? 130.801 133.525 122.584 1.00 128.89 ? 148 LEU D CD1   1 
ATOM   4395 C CD2   . LEU B 2 148 ? 130.741 131.188 123.379 1.00 128.89 ? 148 LEU D CD2   1 
ATOM   4396 N N     . ILE B 2 149 ? 132.997 131.043 118.991 1.00 87.28  ? 149 ILE D N     1 
ATOM   4397 C CA    . ILE B 2 149 ? 134.378 130.652 118.731 1.00 87.28  ? 149 ILE D CA    1 
ATOM   4398 C C     . ILE B 2 149 ? 134.967 131.512 117.651 1.00 87.28  ? 149 ILE D C     1 
ATOM   4399 O O     . ILE B 2 149 ? 136.100 131.980 117.767 1.00 87.28  ? 149 ILE D O     1 
ATOM   4400 C CB    . ILE B 2 149 ? 134.456 129.180 118.320 1.00 129.14 ? 149 ILE D CB    1 
ATOM   4401 C CG1   . ILE B 2 149 ? 134.021 128.310 119.491 1.00 129.14 ? 149 ILE D CG1   1 
ATOM   4402 C CG2   . ILE B 2 149 ? 135.832 128.847 117.896 1.00 129.14 ? 149 ILE D CG2   1 
ATOM   4403 C CD1   . ILE B 2 149 ? 133.757 126.852 119.150 1.00 129.14 ? 149 ILE D CD1   1 
ATOM   4404 N N     . MET B 2 150 ? 134.211 131.719 116.576 1.00 88.80  ? 150 MET D N     1 
ATOM   4405 C CA    . MET B 2 150 ? 134.701 132.501 115.460 1.00 88.80  ? 150 MET D CA    1 
ATOM   4406 C C     . MET B 2 150 ? 135.029 133.912 115.873 1.00 88.80  ? 150 MET D C     1 
ATOM   4407 O O     . MET B 2 150 ? 136.074 134.446 115.505 1.00 88.80  ? 150 MET D O     1 
ATOM   4408 C CB    . MET B 2 150 ? 133.663 132.494 114.371 1.00 127.53 ? 150 MET D CB    1 
ATOM   4409 C CG    . MET B 2 150 ? 133.490 131.159 113.721 1.00 127.53 ? 150 MET D CG    1 
ATOM   4410 S SD    . MET B 2 150 ? 132.074 131.079 112.669 1.00 127.53 ? 150 MET D SD    1 
ATOM   4411 C CE    . MET B 2 150 ? 132.582 132.081 111.299 1.00 127.53 ? 150 MET D CE    1 
ATOM   4412 N N     . GLU B 2 151 ? 134.163 134.529 116.662 1.00 90.10  ? 151 GLU D N     1 
ATOM   4413 C CA    . GLU B 2 151 ? 134.435 135.877 117.098 1.00 90.10  ? 151 GLU D CA    1 
ATOM   4414 C C     . GLU B 2 151 ? 135.666 135.921 117.977 1.00 90.10  ? 151 GLU D C     1 
ATOM   4415 O O     . GLU B 2 151 ? 136.493 136.828 117.843 1.00 90.10  ? 151 GLU D O     1 
ATOM   4416 C CB    . GLU B 2 151 ? 133.229 136.439 117.836 1.00 121.02 ? 151 GLU D CB    1 
ATOM   4417 C CG    . GLU B 2 151 ? 132.029 136.700 116.953 1.00 121.02 ? 151 GLU D CG    1 
ATOM   4418 C CD    . GLU B 2 151 ? 130.772 137.063 117.721 1.00 121.02 ? 151 GLU D CD    1 
ATOM   4419 O OE1   . GLU B 2 151 ? 130.714 136.820 118.926 1.00 121.02 ? 151 GLU D OE1   1 
ATOM   4420 O OE2   . GLU B 2 151 ? 129.837 137.596 117.117 1.00 121.02 ? 151 GLU D OE2   1 
ATOM   4421 N N     . ALA B 2 152 ? 135.818 134.952 118.867 1.00 88.64  ? 152 ALA D N     1 
ATOM   4422 C CA    . ALA B 2 152 ? 136.981 134.934 119.741 1.00 88.64  ? 152 ALA D CA    1 
ATOM   4423 C C     . ALA B 2 152 ? 138.272 134.821 118.960 1.00 88.64  ? 152 ALA D C     1 
ATOM   4424 O O     . ALA B 2 152 ? 139.281 135.423 119.323 1.00 88.64  ? 152 ALA D O     1 
ATOM   4425 C CB    . ALA B 2 152 ? 136.868 133.768 120.711 1.00 120.87 ? 152 ALA D CB    1 
ATOM   4426 N N     . ILE B 2 153 ? 138.262 134.041 117.888 1.00 89.14  ? 153 ILE D N     1 
ATOM   4427 C CA    . ILE B 2 153 ? 139.448 133.900 117.060 1.00 89.14  ? 153 ILE D CA    1 
ATOM   4428 C C     . ILE B 2 153 ? 139.759 135.183 116.327 1.00 89.14  ? 153 ILE D C     1 
ATOM   4429 O O     . ILE B 2 153 ? 140.900 135.633 116.326 1.00 89.14  ? 153 ILE D O     1 
ATOM   4430 C CB    . ILE B 2 153 ? 139.276 132.780 116.038 1.00 131.89 ? 153 ILE D CB    1 
ATOM   4431 C CG1   . ILE B 2 153 ? 139.177 131.434 116.715 1.00 131.89 ? 153 ILE D CG1   1 
ATOM   4432 C CG2   . ILE B 2 153 ? 140.443 132.823 115.048 1.00 131.89 ? 153 ILE D CG2   1 
ATOM   4433 C CD1   . ILE B 2 153 ? 138.705 130.348 115.787 1.00 131.89 ? 153 ILE D CD1   1 
ATOM   4434 N N     . LYS B 2 154 ? 138.773 135.783 115.668 1.00 89.61  ? 154 LYS D N     1 
ATOM   4435 C CA    . LYS B 2 154 ? 139.104 136.940 114.849 1.00 89.61  ? 154 LYS D CA    1 
ATOM   4436 C C     . LYS B 2 154 ? 139.607 138.111 115.651 1.00 89.61  ? 154 LYS D C     1 
ATOM   4437 O O     . LYS B 2 154 ? 140.385 138.905 115.123 1.00 89.61  ? 154 LYS D O     1 
ATOM   4438 C CB    . LYS B 2 154 ? 137.953 137.395 113.977 1.00 134.29 ? 154 LYS D CB    1 
ATOM   4439 C CG    . LYS B 2 154 ? 137.798 136.511 112.779 1.00 134.29 ? 154 LYS D CG    1 
ATOM   4440 C CD    . LYS B 2 154 ? 136.702 136.972 111.848 1.00 134.29 ? 154 LYS D CD    1 
ATOM   4441 C CE    . LYS B 2 154 ? 137.068 138.223 111.040 1.00 134.29 ? 154 LYS D CE    1 
ATOM   4442 N NZ    . LYS B 2 154 ? 138.177 138.020 110.025 1.00 134.29 ? 154 LYS D NZ    1 
ATOM   4443 N N     . LYS B 2 155 ? 139.213 138.261 116.899 1.00 90.68  ? 155 LYS D N     1 
ATOM   4444 C CA    . LYS B 2 155 ? 139.780 139.380 117.631 1.00 90.68  ? 155 LYS D CA    1 
ATOM   4445 C C     . LYS B 2 155 ? 141.206 139.116 118.063 1.00 90.68  ? 155 LYS D C     1 
ATOM   4446 O O     . LYS B 2 155 ? 141.874 140.029 118.549 1.00 90.68  ? 155 LYS D O     1 
ATOM   4447 C CB    . LYS B 2 155 ? 138.937 139.766 118.849 1.00 135.90 ? 155 LYS D CB    1 
ATOM   4448 C CG    . LYS B 2 155 ? 138.955 138.827 119.994 1.00 135.90 ? 155 LYS D CG    1 
ATOM   4449 C CD    . LYS B 2 155 ? 138.049 139.334 121.102 1.00 135.90 ? 155 LYS D CD    1 
ATOM   4450 C CE    . LYS B 2 155 ? 138.076 138.412 122.312 1.00 135.90 ? 155 LYS D CE    1 
ATOM   4451 N NZ    . LYS B 2 155 ? 137.182 138.897 123.402 1.00 135.90 ? 155 LYS D NZ    1 
ATOM   4452 N N     . LYS B 2 156 ? 141.685 137.895 117.914 1.00 93.76  ? 156 LYS D N     1 
ATOM   4453 C CA    . LYS B 2 156 ? 143.035 137.534 118.283 1.00 93.76  ? 156 LYS D CA    1 
ATOM   4454 C C     . LYS B 2 156 ? 143.935 137.376 117.071 1.00 93.76  ? 156 LYS D C     1 
ATOM   4455 O O     . LYS B 2 156 ? 145.115 137.715 117.131 1.00 93.76  ? 156 LYS D O     1 
ATOM   4456 C CB    . LYS B 2 156 ? 143.000 136.240 119.084 1.00 140.51 ? 156 LYS D CB    1 
ATOM   4457 C CG    . LYS B 2 156 ? 144.319 135.784 119.637 1.00 140.51 ? 156 LYS D CG    1 
ATOM   4458 C CD    . LYS B 2 156 ? 144.132 134.605 120.551 1.00 140.51 ? 156 LYS D CD    1 
ATOM   4459 C CE    . LYS B 2 156 ? 145.434 134.095 121.066 1.00 140.51 ? 156 LYS D CE    1 
ATOM   4460 N NZ    . LYS B 2 156 ? 145.234 132.938 121.966 1.00 140.51 ? 156 LYS D NZ    1 
ATOM   4461 N N     . HIS B 2 157 ? 143.385 136.908 115.957 1.00 94.07  ? 157 HIS D N     1 
ATOM   4462 C CA    . HIS B 2 157 ? 144.117 136.700 114.710 1.00 94.07  ? 157 HIS D CA    1 
ATOM   4463 C C     . HIS B 2 157 ? 143.390 137.375 113.549 1.00 94.07  ? 157 HIS D C     1 
ATOM   4464 O O     . HIS B 2 157 ? 142.972 136.706 112.604 1.00 94.07  ? 157 HIS D O     1 
ATOM   4465 C CB    . HIS B 2 157 ? 144.250 135.217 114.405 1.00 127.91 ? 157 HIS D CB    1 
ATOM   4466 C CG    . HIS B 2 157 ? 144.915 134.440 115.468 1.00 127.91 ? 157 HIS D CG    1 
ATOM   4467 N ND1   . HIS B 2 157 ? 146.262 134.512 115.691 1.00 127.91 ? 157 HIS D ND1   1 
ATOM   4468 C CD2   . HIS B 2 157 ? 144.430 133.548 116.353 1.00 127.91 ? 157 HIS D CD2   1 
ATOM   4469 C CE1   . HIS B 2 157 ? 146.584 133.712 116.685 1.00 127.91 ? 157 HIS D CE1   1 
ATOM   4470 N NE2   . HIS B 2 157 ? 145.490 133.109 117.101 1.00 127.91 ? 157 HIS D NE2   1 
ATOM   4471 N N     . PRO B 2 158 ? 143.336 138.704 113.549 1.00 94.04  ? 158 PRO D N     1 
ATOM   4472 C CA    . PRO B 2 158 ? 142.509 139.491 112.631 1.00 94.04  ? 158 PRO D CA    1 
ATOM   4473 C C     . PRO B 2 158 ? 142.898 139.452 111.180 1.00 94.04  ? 158 PRO D C     1 
ATOM   4474 O O     . PRO B 2 158 ? 142.100 139.866 110.330 1.00 94.04  ? 158 PRO D O     1 
ATOM   4475 C CB    . PRO B 2 158 ? 142.707 140.900 113.169 1.00 293.32 ? 158 PRO D CB    1 
ATOM   4476 C CG    . PRO B 2 158 ? 144.024 140.844 113.856 1.00 293.32 ? 158 PRO D CG    1 
ATOM   4477 C CD    . PRO B 2 158 ? 144.105 139.528 114.465 1.00 293.32 ? 158 PRO D CD    1 
ATOM   4478 N N     . LYS B 2 159 ? 144.105 139.040 110.853 1.00 94.05  ? 159 LYS D N     1 
ATOM   4479 C CA    . LYS B 2 159 ? 144.561 139.040 109.473 1.00 94.05  ? 159 LYS D CA    1 
ATOM   4480 C C     . LYS B 2 159 ? 144.295 137.739 108.752 1.00 94.05  ? 159 LYS D C     1 
ATOM   4481 O O     . LYS B 2 159 ? 144.617 137.627 107.574 1.00 94.05  ? 159 LYS D O     1 
ATOM   4482 C CB    . LYS B 2 159 ? 146.054 139.318 109.412 1.00 140.95 ? 159 LYS D CB    1 
ATOM   4483 C CG    . LYS B 2 159 ? 146.492 140.653 109.967 1.00 140.95 ? 159 LYS D CG    1 
ATOM   4484 C CD    . LYS B 2 159 ? 145.983 141.809 109.133 1.00 140.95 ? 159 LYS D CD    1 
ATOM   4485 C CE    . LYS B 2 159 ? 146.562 143.137 109.609 1.00 140.95 ? 159 LYS D CE    1 
ATOM   4486 N NZ    . LYS B 2 159 ? 146.046 144.295 108.819 1.00 140.95 ? 159 LYS D NZ    1 
ATOM   4487 N N     . LEU B 2 160 ? 143.741 136.752 109.415 1.00 90.17  ? 160 LEU D N     1 
ATOM   4488 C CA    . LEU B 2 160 ? 143.476 135.485 108.780 1.00 90.17  ? 160 LEU D CA    1 
ATOM   4489 C C     . LEU B 2 160 ? 142.078 135.458 108.217 1.00 90.17  ? 160 LEU D C     1 
ATOM   4490 O O     . LEU B 2 160 ? 141.194 136.144 108.708 1.00 90.17  ? 160 LEU D O     1 
ATOM   4491 C CB    . LEU B 2 160 ? 143.624 134.375 109.762 1.00 133.42 ? 160 LEU D CB    1 
ATOM   4492 C CG    . LEU B 2 160 ? 144.980 134.215 110.375 1.00 133.42 ? 160 LEU D CG    1 
ATOM   4493 C CD1   . LEU B 2 160 ? 144.878 133.097 111.372 1.00 133.42 ? 160 LEU D CD1   1 
ATOM   4494 C CD2   . LEU B 2 160 ? 146.013 133.869 109.310 1.00 133.42 ? 160 LEU D CD2   1 
ATOM   4495 N N     . VAL B 2 161 ? 141.868 134.682 107.198 1.00 89.86  ? 161 VAL D N     1 
ATOM   4496 C CA    . VAL B 2 161 ? 140.538 134.563 106.639 1.00 89.86  ? 161 VAL D CA    1 
ATOM   4497 C C     . VAL B 2 161 ? 139.804 133.493 107.376 1.00 89.86  ? 161 VAL D C     1 
ATOM   4498 O O     . VAL B 2 161 ? 140.324 132.387 107.573 1.00 89.86  ? 161 VAL D O     1 
ATOM   4499 C CB    . VAL B 2 161 ? 140.576 134.230 105.156 1.00 130.66 ? 161 VAL D CB    1 
ATOM   4500 C CG1   . VAL B 2 161 ? 139.172 133.993 104.623 1.00 130.66 ? 161 VAL D CG1   1 
ATOM   4501 C CG2   . VAL B 2 161 ? 141.193 135.349 104.446 1.00 130.66 ? 161 VAL D CG2   1 
ATOM   4502 N N     . MET B 2 162 ? 138.593 133.784 107.768 1.00 91.76  ? 162 MET D N     1 
ATOM   4503 C CA    . MET B 2 162 ? 137.800 132.752 108.386 1.00 91.76  ? 162 MET D CA    1 
ATOM   4504 C C     . MET B 2 162 ? 136.619 132.360 107.532 1.00 91.76  ? 162 MET D C     1 
ATOM   4505 O O     . MET B 2 162 ? 135.849 133.205 107.071 1.00 91.76  ? 162 MET D O     1 
ATOM   4506 C CB    . MET B 2 162 ? 137.352 133.180 109.747 1.00 131.78 ? 162 MET D CB    1 
ATOM   4507 C CG    . MET B 2 162 ? 136.519 132.194 110.351 1.00 131.78 ? 162 MET D CG    1 
ATOM   4508 S SD    . MET B 2 162 ? 136.210 132.632 111.967 1.00 131.78 ? 162 MET D SD    1 
ATOM   4509 C CE    . MET B 2 162 ? 137.656 131.993 112.719 1.00 131.78 ? 162 MET D CE    1 
ATOM   4510 N N     . MET B 2 163 ? 136.477 131.076 107.335 1.00 91.94  ? 163 MET D N     1 
ATOM   4511 C CA    . MET B 2 163 ? 135.417 130.553 106.514 1.00 91.94  ? 163 MET D CA    1 
ATOM   4512 C C     . MET B 2 163 ? 134.585 129.602 107.313 1.00 91.94  ? 163 MET D C     1 
ATOM   4513 O O     . MET B 2 163 ? 135.101 128.850 108.137 1.00 91.94  ? 163 MET D O     1 
ATOM   4514 C CB    . MET B 2 163 ? 135.986 129.881 105.291 1.00 132.04 ? 163 MET D CB    1 
ATOM   4515 C CG    . MET B 2 163 ? 134.954 129.255 104.361 1.00 132.04 ? 163 MET D CG    1 
ATOM   4516 S SD    . MET B 2 163 ? 135.617 128.801 102.740 1.00 132.04 ? 163 MET D SD    1 
ATOM   4517 C CE    . MET B 2 163 ? 136.729 127.453 103.106 1.00 132.04 ? 163 MET D CE    1 
ATOM   4518 N N     . SER B 2 164 ? 133.305 129.628 107.094 1.00 90.33  ? 164 SER D N     1 
ATOM   4519 C CA    . SER B 2 164 ? 132.477 128.697 107.803 1.00 90.33  ? 164 SER D CA    1 
ATOM   4520 C C     . SER B 2 164 ? 131.680 127.869 106.838 1.00 90.33  ? 164 SER D C     1 
ATOM   4521 O O     . SER B 2 164 ? 131.383 128.285 105.723 1.00 90.33  ? 164 SER D O     1 
ATOM   4522 C CB    . SER B 2 164 ? 131.550 129.379 108.736 1.00 121.67 ? 164 SER D CB    1 
ATOM   4523 O OG    . SER B 2 164 ? 130.607 130.173 108.068 1.00 121.67 ? 164 SER D OG    1 
ATOM   4524 N N     . TYR B 2 165 ? 131.352 126.692 107.279 1.00 89.25  ? 165 TYR D N     1 
ATOM   4525 C CA    . TYR B 2 165 ? 130.533 125.791 106.523 1.00 89.25  ? 165 TYR D CA    1 
ATOM   4526 C C     . TYR B 2 165 ? 129.296 125.602 107.350 1.00 89.25  ? 165 TYR D C     1 
ATOM   4527 O O     . TYR B 2 165 ? 129.327 124.928 108.378 1.00 89.25  ? 165 TYR D O     1 
ATOM   4528 C CB    . TYR B 2 165 ? 131.273 124.506 106.274 1.00 123.53 ? 165 TYR D CB    1 
ATOM   4529 C CG    . TYR B 2 165 ? 130.651 123.587 105.330 1.00 123.53 ? 165 TYR D CG    1 
ATOM   4530 C CD1   . TYR B 2 165 ? 130.770 123.785 104.018 1.00 123.53 ? 165 TYR D CD1   1 
ATOM   4531 C CD2   . TYR B 2 165 ? 129.990 122.498 105.761 1.00 123.53 ? 165 TYR D CD2   1 
ATOM   4532 C CE1   . TYR B 2 165 ? 130.226 122.933 103.160 1.00 123.53 ? 165 TYR D CE1   1 
ATOM   4533 C CE2   . TYR B 2 165 ? 129.466 121.654 104.914 1.00 123.53 ? 165 TYR D CE2   1 
ATOM   4534 C CZ    . TYR B 2 165 ? 129.589 121.872 103.623 1.00 123.53 ? 165 TYR D CZ    1 
ATOM   4535 O OH    . TYR B 2 165 ? 129.026 120.996 102.749 1.00 123.53 ? 165 TYR D OH    1 
ATOM   4536 N N     . SER B 2 166 ? 128.226 126.214 106.921 1.00 90.34  ? 166 SER D N     1 
ATOM   4537 C CA    . SER B 2 166 ? 126.994 126.271 107.668 1.00 90.34  ? 166 SER D CA    1 
ATOM   4538 C C     . SER B 2 166 ? 126.002 125.291 107.075 1.00 90.34  ? 166 SER D C     1 
ATOM   4539 O O     . SER B 2 166 ? 125.648 125.399 105.899 1.00 90.34  ? 166 SER D O     1 
ATOM   4540 C CB    . SER B 2 166 ? 126.456 127.689 107.602 1.00 121.68 ? 166 SER D CB    1 
ATOM   4541 O OG    . SER B 2 166 ? 125.173 127.783 108.151 1.00 121.68 ? 166 SER D OG    1 
ATOM   4542 N N     . ILE B 2 167 ? 125.551 124.336 107.864 1.00 89.90  ? 167 ILE D N     1 
ATOM   4543 C CA    . ILE B 2 167 ? 124.659 123.339 107.327 1.00 89.90  ? 167 ILE D CA    1 
ATOM   4544 C C     . ILE B 2 167 ? 123.281 123.520 107.879 1.00 89.90  ? 167 ILE D C     1 
ATOM   4545 O O     . ILE B 2 167 ? 123.104 123.485 109.083 1.00 89.90  ? 167 ILE D O     1 
ATOM   4546 C CB    . ILE B 2 167 ? 125.131 121.957 107.667 1.00 133.02 ? 167 ILE D CB    1 
ATOM   4547 C CG1   . ILE B 2 167 ? 126.531 121.801 107.186 1.00 133.02 ? 167 ILE D CG1   1 
ATOM   4548 C CG2   . ILE B 2 167 ? 124.213 120.979 106.974 1.00 133.02 ? 167 ILE D CG2   1 
ATOM   4549 C CD1   . ILE B 2 167 ? 127.187 120.655 107.799 1.00 133.02 ? 167 ILE D CD1   1 
ATOM   4550 N N     . VAL B 2 168 ? 122.284 123.673 107.031 1.00 89.51  ? 168 VAL D N     1 
ATOM   4551 C CA    . VAL B 2 168 ? 120.915 123.888 107.484 1.00 89.51  ? 168 VAL D CA    1 
ATOM   4552 C C     . VAL B 2 168 ? 120.221 122.537 107.589 1.00 89.51  ? 168 VAL D C     1 
ATOM   4553 O O     . VAL B 2 168 ? 120.117 121.833 106.578 1.00 89.51  ? 168 VAL D O     1 
ATOM   4554 C CB    . VAL B 2 168 ? 120.139 124.786 106.525 1.00 130.15 ? 168 VAL D CB    1 
ATOM   4555 C CG1   . VAL B 2 168 ? 118.758 124.966 107.001 1.00 130.15 ? 168 VAL D CG1   1 
ATOM   4556 C CG2   . VAL B 2 168 ? 120.832 126.074 106.347 1.00 130.15 ? 168 VAL D CG2   1 
ATOM   4557 N N     . PRO B 2 169 ? 119.735 122.160 108.752 1.00 87.83  ? 169 PRO D N     1 
ATOM   4558 C CA    . PRO B 2 169 ? 119.039 120.900 108.958 1.00 87.83  ? 169 PRO D CA    1 
ATOM   4559 C C     . PRO B 2 169 ? 117.772 120.811 108.144 1.00 87.83  ? 169 PRO D C     1 
ATOM   4560 O O     . PRO B 2 169 ? 117.086 121.796 107.952 1.00 87.83  ? 169 PRO D O     1 
ATOM   4561 C CB    . PRO B 2 169 ? 118.730 120.947 110.436 1.00 273.95 ? 169 PRO D CB    1 
ATOM   4562 C CG    . PRO B 2 169 ? 119.726 121.835 110.988 1.00 273.95 ? 169 PRO D CG    1 
ATOM   4563 C CD    . PRO B 2 169 ? 119.981 122.856 109.976 1.00 273.95 ? 169 PRO D CD    1 
ATOM   4564 N N     . SER B 2 170 ? 117.454 119.615 107.693 1.00 92.23  ? 170 SER D N     1 
ATOM   4565 C CA    . SER B 2 170 ? 116.281 119.352 106.885 1.00 92.23  ? 170 SER D CA    1 
ATOM   4566 C C     . SER B 2 170 ? 115.148 118.872 107.738 1.00 92.23  ? 170 SER D C     1 
ATOM   4567 O O     . SER B 2 170 ? 115.355 118.274 108.783 1.00 92.23  ? 170 SER D O     1 
ATOM   4568 C CB    . SER B 2 170 ? 116.576 118.276 105.872 1.00 124.23 ? 170 SER D CB    1 
ATOM   4569 O OG    . SER B 2 170 ? 116.890 117.087 106.533 1.00 124.23 ? 170 SER D OG    1 
ATOM   4570 N N     . GLN B 2 171 ? 113.946 118.982 107.223 1.00 90.90  ? 171 GLN D N     1 
ATOM   4571 C CA    . GLN B 2 171 ? 112.818 118.628 108.063 1.00 90.90  ? 171 GLN D CA    1 
ATOM   4572 C C     . GLN B 2 171 ? 112.549 117.140 108.156 1.00 90.90  ? 171 GLN D C     1 
ATOM   4573 O O     . GLN B 2 171 ? 111.690 116.722 108.932 1.00 90.90  ? 171 GLN D O     1 
ATOM   4574 C CB    . GLN B 2 171 ? 111.566 119.318 107.576 1.00 126.98 ? 171 GLN D CB    1 
ATOM   4575 C CG    . GLN B 2 171 ? 111.648 120.766 107.697 1.00 126.98 ? 171 GLN D CG    1 
ATOM   4576 C CD    . GLN B 2 171 ? 111.942 121.195 109.107 1.00 126.98 ? 171 GLN D CD    1 
ATOM   4577 O OE1   . GLN B 2 171 ? 111.275 120.789 110.067 1.00 126.98 ? 171 GLN D OE1   1 
ATOM   4578 N NE2   . GLN B 2 171 ? 112.957 122.023 109.250 1.00 126.98 ? 171 GLN D NE2   1 
ATOM   4579 N N     . ASN B 2 172 ? 113.232 116.333 107.396 1.00 90.04  ? 172 ASN D N     1 
ATOM   4580 C CA    . ASN B 2 172 ? 113.036 114.920 107.485 1.00 90.04  ? 172 ASN D CA    1 
ATOM   4581 C C     . ASN B 2 172 ? 114.121 114.285 108.306 1.00 90.04  ? 172 ASN D C     1 
ATOM   4582 O O     . ASN B 2 172 ? 114.177 113.057 108.416 1.00 90.04  ? 172 ASN D O     1 
ATOM   4583 C CB    . ASN B 2 172 ? 112.977 114.351 106.095 1.00 121.98 ? 172 ASN D CB    1 
ATOM   4584 C CG    . ASN B 2 172 ? 111.778 114.830 105.367 1.00 121.98 ? 172 ASN D CG    1 
ATOM   4585 O OD1   . ASN B 2 172 ? 110.674 114.374 105.619 1.00 121.98 ? 172 ASN D OD1   1 
ATOM   4586 N ND2   . ASN B 2 172 ? 111.967 115.771 104.471 1.00 121.98 ? 172 ASN D ND2   1 
ATOM   4587 N N     . MET B 2 173 ? 114.958 115.104 108.916 1.00 90.92  ? 173 MET D N     1 
ATOM   4588 C CA    . MET B 2 173 ? 116.057 114.640 109.734 1.00 90.92  ? 173 MET D CA    1 
ATOM   4589 C C     . MET B 2 173 ? 115.860 115.228 111.122 1.00 90.92  ? 173 MET D C     1 
ATOM   4590 O O     . MET B 2 173 ? 114.743 115.597 111.485 1.00 90.92  ? 173 MET D O     1 
ATOM   4591 C CB    . MET B 2 173 ? 117.395 115.020 109.120 1.00 130.57 ? 173 MET D CB    1 
ATOM   4592 C CG    . MET B 2 173 ? 117.642 114.391 107.751 1.00 130.57 ? 173 MET D CG    1 
ATOM   4593 S SD    . MET B 2 173 ? 117.769 112.608 107.757 1.00 130.57 ? 173 MET D SD    1 
ATOM   4594 C CE    . MET B 2 173 ? 119.388 112.307 108.454 1.00 130.57 ? 173 MET D CE    1 
ATOM   4595 N N     . ASP B 2 174 ? 116.900 115.282 111.933 1.00 89.99  ? 174 ASP D N     1 
ATOM   4596 C CA    . ASP B 2 174 ? 116.713 115.617 113.332 1.00 89.99  ? 174 ASP D CA    1 
ATOM   4597 C C     . ASP B 2 174 ? 116.641 117.112 113.635 1.00 89.99  ? 174 ASP D C     1 
ATOM   4598 O O     . ASP B 2 174 ? 117.484 117.661 114.339 1.00 89.99  ? 174 ASP D O     1 
ATOM   4599 C CB    . ASP B 2 174 ? 117.826 114.979 114.131 1.00 115.70 ? 174 ASP D CB    1 
ATOM   4600 C CG    . ASP B 2 174 ? 119.172 115.322 113.598 1.00 115.70 ? 174 ASP D CG    1 
ATOM   4601 O OD1   . ASP B 2 174 ? 119.245 115.702 112.430 1.00 115.70 ? 174 ASP D OD1   1 
ATOM   4602 O OD2   . ASP B 2 174 ? 120.164 115.165 114.324 1.00 115.70 ? 174 ASP D OD2   1 
ATOM   4603 N N     . CYS B 2 175 ? 115.564 117.750 113.198 1.00 86.88  ? 175 CYS D N     1 
ATOM   4604 C CA    . CYS B 2 175 ? 115.351 119.157 113.490 1.00 86.88  ? 175 CYS D CA    1 
ATOM   4605 C C     . CYS B 2 175 ? 114.573 119.413 114.755 1.00 86.88  ? 175 CYS D C     1 
ATOM   4606 O O     . CYS B 2 175 ? 113.730 118.619 115.162 1.00 86.88  ? 175 CYS D O     1 
ATOM   4607 C CB    . CYS B 2 175 ? 114.559 119.838 112.406 1.00 117.02 ? 175 CYS D CB    1 
ATOM   4608 S SG    . CYS B 2 175 ? 115.418 120.092 110.954 1.00 117.02 ? 175 CYS D SG    1 
ATOM   4609 N N     . SER B 2 176 ? 114.799 120.580 115.317 1.00 83.44  ? 176 SER D N     1 
ATOM   4610 C CA    . SER B 2 176 ? 114.072 121.091 116.452 1.00 83.44  ? 176 SER D CA    1 
ATOM   4611 C C     . SER B 2 176 ? 112.925 121.985 116.013 1.00 83.44  ? 176 SER D C     1 
ATOM   4612 O O     . SER B 2 176 ? 112.945 122.546 114.930 1.00 83.44  ? 176 SER D O     1 
ATOM   4613 C CB    . SER B 2 176 ? 114.990 121.892 117.309 1.00 112.39 ? 176 SER D CB    1 
ATOM   4614 O OG    . SER B 2 176 ? 114.240 122.527 118.281 1.00 112.39 ? 176 SER D OG    1 
ATOM   4615 N N     . THR B 2 177 ? 111.941 122.169 116.887 1.00 80.15  ? 177 THR D N     1 
ATOM   4616 C CA    . THR B 2 177 ? 110.797 123.010 116.554 1.00 80.15  ? 177 THR D CA    1 
ATOM   4617 C C     . THR B 2 177 ? 111.134 124.465 116.662 1.00 80.15  ? 177 THR D C     1 
ATOM   4618 O O     . THR B 2 177 ? 110.336 125.322 116.287 1.00 80.15  ? 177 THR D O     1 
ATOM   4619 C CB    . THR B 2 177 ? 109.627 122.748 117.457 1.00 112.20 ? 177 THR D CB    1 
ATOM   4620 O OG1   . THR B 2 177 ? 109.999 123.110 118.781 1.00 112.20 ? 177 THR D OG1   1 
ATOM   4621 C CG2   . THR B 2 177 ? 109.279 121.308 117.428 1.00 112.20 ? 177 THR D CG2   1 
ATOM   4622 N N     . ILE B 2 178 ? 112.300 124.757 117.163 1.00 79.31  ? 178 ILE D N     1 
ATOM   4623 C CA    . ILE B 2 178 ? 112.758 126.100 117.281 1.00 79.31  ? 178 ILE D CA    1 
ATOM   4624 C C     . ILE B 2 178 ? 113.829 126.378 116.256 1.00 79.31  ? 178 ILE D C     1 
ATOM   4625 O O     . ILE B 2 178 ? 114.547 127.360 116.365 1.00 79.31  ? 178 ILE D O     1 
ATOM   4626 C CB    . ILE B 2 178 ? 113.249 126.404 118.690 1.00 117.35 ? 178 ILE D CB    1 
ATOM   4627 C CG1   . ILE B 2 178 ? 114.367 125.467 119.047 1.00 117.35 ? 178 ILE D CG1   1 
ATOM   4628 C CG2   . ILE B 2 178 ? 112.140 126.287 119.637 1.00 117.35 ? 178 ILE D CG2   1 
ATOM   4629 C CD1   . ILE B 2 178 ? 115.176 125.831 120.214 1.00 117.35 ? 178 ILE D CD1   1 
ATOM   4630 N N     . LEU B 2 179 ? 113.905 125.553 115.227 1.00 78.52  ? 179 LEU D N     1 
ATOM   4631 C CA    . LEU B 2 179 ? 114.896 125.769 114.184 1.00 78.52  ? 179 LEU D CA    1 
ATOM   4632 C C     . LEU B 2 179 ? 114.919 127.188 113.669 1.00 78.52  ? 179 LEU D C     1 
ATOM   4633 O O     . LEU B 2 179 ? 116.015 127.748 113.579 1.00 78.52  ? 179 LEU D O     1 
ATOM   4634 C CB    . LEU B 2 179 ? 114.709 124.774 113.033 1.00 116.18 ? 179 LEU D CB    1 
ATOM   4635 C CG    . LEU B 2 179 ? 115.566 124.952 111.800 1.00 116.18 ? 179 LEU D CG    1 
ATOM   4636 C CD1   . LEU B 2 179 ? 116.915 124.796 112.115 1.00 116.18 ? 179 LEU D CD1   1 
ATOM   4637 C CD2   . LEU B 2 179 ? 115.184 123.984 110.769 1.00 116.18 ? 179 LEU D CD2   1 
ATOM   4638 N N     . PRO B 2 180 ? 113.808 127.818 113.326 1.00 79.35  ? 180 PRO D N     1 
ATOM   4639 C CA    . PRO B 2 180 ? 113.835 129.172 112.810 1.00 79.35  ? 180 PRO D CA    1 
ATOM   4640 C C     . PRO B 2 180 ? 114.400 130.172 113.756 1.00 79.35  ? 180 PRO D C     1 
ATOM   4641 O O     . PRO B 2 180 ? 114.934 131.212 113.333 1.00 79.35  ? 180 PRO D O     1 
ATOM   4642 C CB    . PRO B 2 180 ? 112.367 129.445 112.553 1.00 247.50 ? 180 PRO D CB    1 
ATOM   4643 C CG    . PRO B 2 180 ? 111.760 128.111 112.442 1.00 247.50 ? 180 PRO D CG    1 
ATOM   4644 C CD    . PRO B 2 180 ? 112.464 127.300 113.399 1.00 247.50 ? 180 PRO D CD    1 
ATOM   4645 N N     . TYR B 2 181 ? 114.342 129.902 115.025 1.00 81.25  ? 181 TYR D N     1 
ATOM   4646 C CA    . TYR B 2 181 ? 114.890 130.860 115.942 1.00 81.25  ? 181 TYR D CA    1 
ATOM   4647 C C     . TYR B 2 181 ? 116.366 130.690 115.957 1.00 81.25  ? 181 TYR D C     1 
ATOM   4648 O O     . TYR B 2 181 ? 117.111 131.654 115.801 1.00 81.25  ? 181 TYR D O     1 
ATOM   4649 C CB    . TYR B 2 181 ? 114.352 130.668 117.338 1.00 112.46 ? 181 TYR D CB    1 
ATOM   4650 C CG    . TYR B 2 181 ? 112.984 131.139 117.615 1.00 112.46 ? 181 TYR D CG    1 
ATOM   4651 C CD1   . TYR B 2 181 ? 112.273 131.874 116.731 1.00 112.46 ? 181 TYR D CD1   1 
ATOM   4652 C CD2   . TYR B 2 181 ? 112.437 130.856 118.769 1.00 112.46 ? 181 TYR D CD2   1 
ATOM   4653 C CE1   . TYR B 2 181 ? 111.053 132.311 117.049 1.00 112.46 ? 181 TYR D CE1   1 
ATOM   4654 C CE2   . TYR B 2 181 ? 111.251 131.277 119.075 1.00 112.46 ? 181 TYR D CE2   1 
ATOM   4655 C CZ    . TYR B 2 181 ? 110.565 132.010 118.227 1.00 112.46 ? 181 TYR D CZ    1 
ATOM   4656 O OH    . TYR B 2 181 ? 109.344 132.456 118.545 1.00 112.46 ? 181 TYR D OH    1 
ATOM   4657 N N     . ASN B 2 182 ? 116.813 129.474 116.097 1.00 81.83  ? 182 ASN D N     1 
ATOM   4658 C CA    . ASN B 2 182 ? 118.235 129.325 116.209 1.00 81.83  ? 182 ASN D CA    1 
ATOM   4659 C C     . ASN B 2 182 ? 118.893 129.729 114.923 1.00 81.83  ? 182 ASN D C     1 
ATOM   4660 O O     . ASN B 2 182 ? 119.995 130.274 114.927 1.00 81.83  ? 182 ASN D O     1 
ATOM   4661 C CB    . ASN B 2 182 ? 118.576 127.924 116.540 1.00 110.86 ? 182 ASN D CB    1 
ATOM   4662 C CG    . ASN B 2 182 ? 118.233 127.545 117.896 1.00 110.86 ? 182 ASN D CG    1 
ATOM   4663 O OD1   . ASN B 2 182 ? 118.023 128.345 118.818 1.00 110.86 ? 182 ASN D OD1   1 
ATOM   4664 N ND2   . ASN B 2 182 ? 118.175 126.270 118.060 1.00 110.86 ? 182 ASN D ND2   1 
ATOM   4665 N N     . ALA B 2 183 ? 118.219 129.507 113.819 1.00 80.89  ? 183 ALA D N     1 
ATOM   4666 C CA    . ALA B 2 183 ? 118.799 129.822 112.541 1.00 80.89  ? 183 ALA D CA    1 
ATOM   4667 C C     . ALA B 2 183 ? 119.003 131.308 112.349 1.00 80.89  ? 183 ALA D C     1 
ATOM   4668 O O     . ALA B 2 183 ? 120.072 131.703 111.885 1.00 80.89  ? 183 ALA D O     1 
ATOM   4669 C CB    . ALA B 2 183 ? 117.946 129.260 111.429 1.00 110.30 ? 183 ALA D CB    1 
ATOM   4670 N N     . ILE B 2 184 ? 118.046 132.173 112.693 1.00 77.71  ? 184 ILE D N     1 
ATOM   4671 C CA    . ILE B 2 184 ? 118.430 133.538 112.402 1.00 77.71  ? 184 ILE D CA    1 
ATOM   4672 C C     . ILE B 2 184 ? 119.178 134.149 113.546 1.00 77.71  ? 184 ILE D C     1 
ATOM   4673 O O     . ILE B 2 184 ? 119.945 135.096 113.335 1.00 77.71  ? 184 ILE D O     1 
ATOM   4674 C CB    . ILE B 2 184 ? 117.318 134.462 111.953 1.00 114.98 ? 184 ILE D CB    1 
ATOM   4675 C CG1   . ILE B 2 184 ? 116.461 134.881 113.078 1.00 114.98 ? 184 ILE D CG1   1 
ATOM   4676 C CG2   . ILE B 2 184 ? 116.573 133.828 110.877 1.00 114.98 ? 184 ILE D CG2   1 
ATOM   4677 C CD1   . ILE B 2 184 ? 115.636 136.107 112.698 1.00 114.98 ? 184 ILE D CD1   1 
ATOM   4678 N N     . LEU B 2 185 ? 119.059 133.604 114.733 1.00 78.76  ? 185 LEU D N     1 
ATOM   4679 C CA    . LEU B 2 185 ? 119.856 134.114 115.814 1.00 78.76  ? 185 LEU D CA    1 
ATOM   4680 C C     . LEU B 2 185 ? 121.316 133.873 115.506 1.00 78.76  ? 185 LEU D C     1 
ATOM   4681 O O     . LEU B 2 185 ? 122.175 134.698 115.836 1.00 78.76  ? 185 LEU D O     1 
ATOM   4682 C CB    . LEU B 2 185 ? 119.452 133.476 117.131 1.00 116.53 ? 185 LEU D CB    1 
ATOM   4683 C CG    . LEU B 2 185 ? 118.064 133.793 117.691 1.00 116.53 ? 185 LEU D CG    1 
ATOM   4684 C CD1   . LEU B 2 185 ? 117.743 132.801 118.827 1.00 116.53 ? 185 LEU D CD1   1 
ATOM   4685 C CD2   . LEU B 2 185 ? 117.956 135.232 118.176 1.00 116.53 ? 185 LEU D CD2   1 
ATOM   4686 N N     . SER B 2 186 ? 121.619 132.752 114.845 1.00 81.16  ? 186 SER D N     1 
ATOM   4687 C CA    . SER B 2 186 ? 122.995 132.483 114.486 1.00 81.16  ? 186 SER D CA    1 
ATOM   4688 C C     . SER B 2 186 ? 123.413 133.099 113.157 1.00 81.16  ? 186 SER D C     1 
ATOM   4689 O O     . SER B 2 186 ? 124.554 133.543 113.058 1.00 81.16  ? 186 SER D O     1 
ATOM   4690 C CB    . SER B 2 186 ? 123.249 131.000 114.505 1.00 109.32 ? 186 SER D CB    1 
ATOM   4691 O OG    . SER B 2 186 ? 122.371 130.369 113.649 1.00 109.32 ? 186 SER D OG    1 
ATOM   4692 N N     . LEU B 2 187 ? 122.521 133.275 112.175 1.00 81.17  ? 187 LEU D N     1 
ATOM   4693 C CA    . LEU B 2 187 ? 122.954 133.996 110.976 1.00 81.17  ? 187 LEU D CA    1 
ATOM   4694 C C     . LEU B 2 187 ? 123.357 135.399 111.353 1.00 81.17  ? 187 LEU D C     1 
ATOM   4695 O O     . LEU B 2 187 ? 124.295 135.962 110.791 1.00 81.17  ? 187 LEU D O     1 
ATOM   4696 C CB    . LEU B 2 187 ? 121.880 134.065 109.895 1.00 120.10 ? 187 LEU D CB    1 
ATOM   4697 C CG    . LEU B 2 187 ? 121.491 132.839 109.114 1.00 120.10 ? 187 LEU D CG    1 
ATOM   4698 C CD1   . LEU B 2 187 ? 120.232 133.135 108.314 1.00 120.10 ? 187 LEU D CD1   1 
ATOM   4699 C CD2   . LEU B 2 187 ? 122.609 132.457 108.184 1.00 120.10 ? 187 LEU D CD2   1 
ATOM   4700 N N     . ASP B 2 188 ? 122.682 135.951 112.334 1.00 78.37  ? 188 ASP D N     1 
ATOM   4701 C CA    . ASP B 2 188 ? 122.998 137.271 112.804 1.00 78.37  ? 188 ASP D CA    1 
ATOM   4702 C C     . ASP B 2 188 ? 124.424 137.386 113.253 1.00 78.37  ? 188 ASP D C     1 
ATOM   4703 O O     . ASP B 2 188 ? 125.003 138.470 113.163 1.00 78.37  ? 188 ASP D O     1 
ATOM   4704 C CB    . ASP B 2 188 ? 122.087 137.623 113.957 1.00 100.76 ? 188 ASP D CB    1 
ATOM   4705 C CG    . ASP B 2 188 ? 122.236 139.044 114.416 1.00 100.76 ? 188 ASP D CG    1 
ATOM   4706 O OD1   . ASP B 2 188 ? 121.933 139.924 113.620 1.00 100.76 ? 188 ASP D OD1   1 
ATOM   4707 O OD2   . ASP B 2 188 ? 122.610 139.298 115.574 1.00 100.76 ? 188 ASP D OD2   1 
ATOM   4708 N N     . LYS B 2 189 ? 125.013 136.338 113.780 1.00 81.79  ? 189 LYS D N     1 
ATOM   4709 C CA    . LYS B 2 189 ? 126.374 136.500 114.229 1.00 81.79  ? 189 LYS D CA    1 
ATOM   4710 C C     . LYS B 2 189 ? 127.336 136.149 113.116 1.00 81.79  ? 189 LYS D C     1 
ATOM   4711 O O     . LYS B 2 189 ? 128.384 136.771 112.990 1.00 81.79  ? 189 LYS D O     1 
ATOM   4712 C CB    . LYS B 2 189 ? 126.620 135.647 115.466 1.00 122.57 ? 189 LYS D CB    1 
ATOM   4713 C CG    . LYS B 2 189 ? 125.695 135.954 116.643 1.00 122.57 ? 189 LYS D CG    1 
ATOM   4714 C CD    . LYS B 2 189 ? 125.912 137.347 117.203 1.00 122.57 ? 189 LYS D CD    1 
ATOM   4715 C CE    . LYS B 2 189 ? 124.961 137.656 118.332 1.00 122.57 ? 189 LYS D CE    1 
ATOM   4716 N NZ    . LYS B 2 189 ? 123.540 137.800 117.852 1.00 122.57 ? 189 LYS D NZ    1 
ATOM   4717 N N     . LEU B 2 190 ? 126.971 135.206 112.255 1.00 82.03  ? 190 LEU D N     1 
ATOM   4718 C CA    . LEU B 2 190 ? 127.855 134.861 111.167 1.00 82.03  ? 190 LEU D CA    1 
ATOM   4719 C C     . LEU B 2 190 ? 128.053 136.050 110.268 1.00 82.03  ? 190 LEU D C     1 
ATOM   4720 O O     . LEU B 2 190 ? 129.163 136.295 109.787 1.00 82.03  ? 190 LEU D O     1 
ATOM   4721 C CB    . LEU B 2 190 ? 127.316 133.687 110.375 1.00 121.37 ? 190 LEU D CB    1 
ATOM   4722 C CG    . LEU B 2 190 ? 127.267 132.340 111.056 1.00 121.37 ? 190 LEU D CG    1 
ATOM   4723 C CD1   . LEU B 2 190 ? 126.525 131.366 110.180 1.00 121.37 ? 190 LEU D CD1   1 
ATOM   4724 C CD2   . LEU B 2 190 ? 128.664 131.831 111.367 1.00 121.37 ? 190 LEU D CD2   1 
ATOM   4725 N N     . THR B 2 191 ? 127.017 136.852 110.109 1.00 80.10  ? 191 THR D N     1 
ATOM   4726 C CA    . THR B 2 191 ? 127.043 138.011 109.228 1.00 80.10  ? 191 THR D CA    1 
ATOM   4727 C C     . THR B 2 191 ? 128.063 139.033 109.678 1.00 80.10  ? 191 THR D C     1 
ATOM   4728 O O     . THR B 2 191 ? 128.459 139.886 108.896 1.00 80.10  ? 191 THR D O     1 
ATOM   4729 C CB    . THR B 2 191 ? 125.644 138.645 109.168 1.00 112.13 ? 191 THR D CB    1 
ATOM   4730 O OG1   . THR B 2 191 ? 124.690 137.662 108.732 1.00 112.13 ? 191 THR D OG1   1 
ATOM   4731 C CG2   . THR B 2 191 ? 125.588 139.784 108.175 1.00 112.13 ? 191 THR D CG2   1 
ATOM   4732 N N     . SER B 2 192 ? 128.488 138.985 110.919 1.00 80.08  ? 192 SER D N     1 
ATOM   4733 C CA    . SER B 2 192 ? 129.464 139.913 111.454 1.00 80.08  ? 192 SER D CA    1 
ATOM   4734 C C     . SER B 2 192 ? 130.815 139.281 111.747 1.00 80.08  ? 192 SER D C     1 
ATOM   4735 O O     . SER B 2 192 ? 131.686 139.963 112.274 1.00 80.08  ? 192 SER D O     1 
ATOM   4736 C CB    . SER B 2 192 ? 128.942 140.528 112.744 1.00 107.86 ? 192 SER D CB    1 
ATOM   4737 O OG    . SER B 2 192 ? 127.771 141.283 112.527 1.00 107.86 ? 192 SER D OG    1 
ATOM   4738 N N     . CYS B 2 193 ? 131.010 137.999 111.474 1.00 87.90  ? 193 CYS D N     1 
ATOM   4739 C CA    . CYS B 2 193 ? 132.288 137.382 111.792 1.00 87.90  ? 193 CYS D CA    1 
ATOM   4740 C C     . CYS B 2 193 ? 132.879 136.498 110.720 1.00 87.90  ? 193 CYS D C     1 
ATOM   4741 O O     . CYS B 2 193 ? 134.091 136.333 110.708 1.00 87.90  ? 193 CYS D O     1 
ATOM   4742 C CB    . CYS B 2 193 ? 132.187 136.581 113.074 1.00 118.39 ? 193 CYS D CB    1 
ATOM   4743 S SG    . CYS B 2 193 ? 131.157 135.174 113.014 1.00 118.39 ? 193 CYS D SG    1 
ATOM   4744 N N     . ALA B 2 194 ? 132.113 135.931 109.820 1.00 89.12  ? 194 ALA D N     1 
ATOM   4745 C CA    . ALA B 2 194 ? 132.723 135.135 108.777 1.00 89.12  ? 194 ALA D CA    1 
ATOM   4746 C C     . ALA B 2 194 ? 133.219 136.037 107.660 1.00 89.12  ? 194 ALA D C     1 
ATOM   4747 O O     . ALA B 2 194 ? 132.626 137.071 107.385 1.00 89.12  ? 194 ALA D O     1 
ATOM   4748 C CB    . ALA B 2 194 ? 131.726 134.137 108.209 1.00 121.53 ? 194 ALA D CB    1 
ATOM   4749 N N     . ASP B 2 195 ? 134.299 135.650 107.005 1.00 90.94  ? 195 ASP D N     1 
ATOM   4750 C CA    . ASP B 2 195 ? 134.676 136.365 105.804 1.00 90.94  ? 195 ASP D CA    1 
ATOM   4751 C C     . ASP B 2 195 ? 134.025 135.699 104.618 1.00 90.94  ? 195 ASP D C     1 
ATOM   4752 O O     . ASP B 2 195 ? 133.597 136.359 103.678 1.00 90.94  ? 195 ASP D O     1 
ATOM   4753 C CB    . ASP B 2 195 ? 136.182 136.368 105.647 1.00 116.92 ? 195 ASP D CB    1 
ATOM   4754 C CG    . ASP B 2 195 ? 136.892 137.131 106.755 1.00 116.92 ? 195 ASP D CG    1 
ATOM   4755 O OD1   . ASP B 2 195 ? 136.717 138.351 106.809 1.00 116.92 ? 195 ASP D OD1   1 
ATOM   4756 O OD2   . ASP B 2 195 ? 137.624 136.525 107.567 1.00 116.92 ? 195 ASP D OD2   1 
ATOM   4757 N N     . ILE B 2 196 ? 133.939 134.392 104.667 1.00 88.52  ? 196 ILE D N     1 
ATOM   4758 C CA    . ILE B 2 196 ? 133.306 133.578 103.654 1.00 88.52  ? 196 ILE D CA    1 
ATOM   4759 C C     . ILE B 2 196 ? 132.363 132.639 104.366 1.00 88.52  ? 196 ILE D C     1 
ATOM   4760 O O     . ILE B 2 196 ? 132.766 131.994 105.331 1.00 88.52  ? 196 ILE D O     1 
ATOM   4761 C CB    . ILE B 2 196 ? 134.329 132.745 102.877 1.00 130.98 ? 196 ILE D CB    1 
ATOM   4762 C CG1   . ILE B 2 196 ? 135.374 133.627 102.241 1.00 130.98 ? 196 ILE D CG1   1 
ATOM   4763 C CG2   . ILE B 2 196 ? 133.630 131.896 101.868 1.00 130.98 ? 196 ILE D CG2   1 
ATOM   4764 C CD1   . ILE B 2 196 ? 136.565 132.849 101.690 1.00 130.98 ? 196 ILE D CD1   1 
ATOM   4765 N N     . SER B 2 197 ? 131.134 132.535 103.945 1.00 87.85  ? 197 SER D N     1 
ATOM   4766 C CA    . SER B 2 197 ? 130.315 131.543 104.618 1.00 87.85  ? 197 SER D CA    1 
ATOM   4767 C C     . SER B 2 197 ? 129.501 130.784 103.619 1.00 87.85  ? 197 SER D C     1 
ATOM   4768 O O     . SER B 2 197 ? 128.746 131.384 102.852 1.00 87.85  ? 197 SER D O     1 
ATOM   4769 C CB    . SER B 2 197 ? 129.414 132.181 105.632 1.00 118.33 ? 197 SER D CB    1 
ATOM   4770 O OG    . SER B 2 197 ? 128.670 131.189 106.281 1.00 118.33 ? 197 SER D OG    1 
ATOM   4771 N N     . MET B 2 198 ? 129.646 129.484 103.601 1.00 90.23  ? 198 MET D N     1 
ATOM   4772 C CA    . MET B 2 198 ? 128.917 128.696 102.631 1.00 90.23  ? 198 MET D CA    1 
ATOM   4773 C C     . MET B 2 198 ? 127.741 128.036 103.289 1.00 90.23  ? 198 MET D C     1 
ATOM   4774 O O     . MET B 2 198 ? 127.873 127.481 104.371 1.00 90.23  ? 198 MET D O     1 
ATOM   4775 C CB    . MET B 2 198 ? 129.831 127.659 102.007 1.00 129.58 ? 198 MET D CB    1 
ATOM   4776 C CG    . MET B 2 198 ? 130.910 128.319 101.238 1.00 129.58 ? 198 MET D CG    1 
ATOM   4777 S SD    . MET B 2 198 ? 132.084 127.223 100.548 1.00 129.58 ? 198 MET D SD    1 
ATOM   4778 C CE    . MET B 2 198 ? 133.189 128.392 99.757  1.00 129.58 ? 198 MET D CE    1 
ATOM   4779 N N     . ILE B 2 199 ? 126.585 128.095 102.657 1.00 89.38  ? 199 ILE D N     1 
ATOM   4780 C CA    . ILE B 2 199 ? 125.401 127.495 103.221 1.00 89.38  ? 199 ILE D CA    1 
ATOM   4781 C C     . ILE B 2 199 ? 124.994 126.344 102.370 1.00 89.38  ? 199 ILE D C     1 
ATOM   4782 O O     . ILE B 2 199 ? 124.756 126.499 101.170 1.00 89.38  ? 199 ILE D O     1 
ATOM   4783 C CB    . ILE B 2 199 ? 124.239 128.470 103.324 1.00 132.25 ? 199 ILE D CB    1 
ATOM   4784 C CG1   . ILE B 2 199 ? 124.605 129.595 104.243 1.00 132.25 ? 199 ILE D CG1   1 
ATOM   4785 C CG2   . ILE B 2 199 ? 123.016 127.733 103.845 1.00 132.25 ? 199 ILE D CG2   1 
ATOM   4786 C CD1   . ILE B 2 199 ? 123.597 130.720 104.270 1.00 132.25 ? 199 ILE D CD1   1 
ATOM   4787 N N     . ILE B 2 200 ? 124.882 125.195 102.974 1.00 90.21  ? 200 ILE D N     1 
ATOM   4788 C CA    . ILE B 2 200 ? 124.440 124.031 102.265 1.00 90.21  ? 200 ILE D CA    1 
ATOM   4789 C C     . ILE B 2 200 ? 123.159 123.571 102.922 1.00 90.21  ? 200 ILE D C     1 
ATOM   4790 O O     . ILE B 2 200 ? 123.065 123.550 104.149 1.00 90.21  ? 200 ILE D O     1 
ATOM   4791 C CB    . ILE B 2 200 ? 125.541 122.973 102.221 1.00 133.48 ? 200 ILE D CB    1 
ATOM   4792 C CG1   . ILE B 2 200 ? 125.084 121.778 101.405 1.00 133.48 ? 200 ILE D CG1   1 
ATOM   4793 C CG2   . ILE B 2 200 ? 125.943 122.581 103.601 1.00 133.48 ? 200 ILE D CG2   1 
ATOM   4794 C CD1   . ILE B 2 200 ? 126.212 120.878 100.939 1.00 133.48 ? 200 ILE D CD1   1 
ATOM   4795 N N     . ASP B 2 201 ? 122.148 123.337 102.131 1.00 91.24  ? 201 ASP D N     1 
ATOM   4796 C CA    . ASP B 2 201 ? 120.830 123.012 102.637 1.00 91.24  ? 201 ASP D CA    1 
ATOM   4797 C C     . ASP B 2 201 ? 120.505 121.522 102.580 1.00 91.24  ? 201 ASP D C     1 
ATOM   4798 O O     . ASP B 2 201 ? 120.375 120.947 101.497 1.00 91.24  ? 201 ASP D O     1 
ATOM   4799 C CB    . ASP B 2 201 ? 119.782 123.760 101.851 1.00 117.31 ? 201 ASP D CB    1 
ATOM   4800 C CG    . ASP B 2 201 ? 118.446 123.590 102.455 1.00 117.31 ? 201 ASP D CG    1 
ATOM   4801 O OD1   . ASP B 2 201 ? 118.360 122.856 103.443 1.00 117.31 ? 201 ASP D OD1   1 
ATOM   4802 O OD2   . ASP B 2 201 ? 117.477 124.169 101.972 1.00 117.31 ? 201 ASP D OD2   1 
ATOM   4803 N N     . ASN B 2 202 ? 120.300 120.897 103.741 1.00 89.92  ? 202 ASN D N     1 
ATOM   4804 C CA    . ASN B 2 202 ? 120.011 119.483 103.722 1.00 89.92  ? 202 ASN D CA    1 
ATOM   4805 C C     . ASN B 2 202 ? 118.667 119.180 103.077 1.00 89.92  ? 202 ASN D C     1 
ATOM   4806 O O     . ASN B 2 202 ? 118.453 118.044 102.654 1.00 89.92  ? 202 ASN D O     1 
ATOM   4807 C CB    . ASN B 2 202 ? 120.106 118.875 105.110 1.00 121.82 ? 202 ASN D CB    1 
ATOM   4808 C CG    . ASN B 2 202 ? 121.502 118.658 105.560 1.00 121.82 ? 202 ASN D CG    1 
ATOM   4809 O OD1   . ASN B 2 202 ? 122.440 118.740 104.789 1.00 121.82 ? 202 ASN D OD1   1 
ATOM   4810 N ND2   . ASN B 2 202 ? 121.662 118.343 106.821 1.00 121.82 ? 202 ASN D ND2   1 
ATOM   4811 N N     . ASP B 2 203 ? 117.751 120.133 102.991 1.00 89.17  ? 203 ASP D N     1 
ATOM   4812 C CA    . ASP B 2 203 ? 116.495 119.834 102.337 1.00 89.17  ? 203 ASP D CA    1 
ATOM   4813 C C     . ASP B 2 203 ? 116.716 119.648 100.860 1.00 89.17  ? 203 ASP D C     1 
ATOM   4814 O O     . ASP B 2 203 ? 115.929 118.958 100.217 1.00 89.17  ? 203 ASP D O     1 
ATOM   4815 C CB    . ASP B 2 203 ? 115.435 120.934 102.498 1.00 114.65 ? 203 ASP D CB    1 
ATOM   4816 C CG    . ASP B 2 203 ? 114.606 120.919 103.836 1.00 114.65 ? 203 ASP D CG    1 
ATOM   4817 O OD1   . ASP B 2 203 ? 114.447 119.910 104.538 1.00 114.65 ? 203 ASP D OD1   1 
ATOM   4818 O OD2   . ASP B 2 203 ? 114.050 121.983 104.146 1.00 114.65 ? 203 ASP D OD2   1 
ATOM   4819 N N     . SER B 2 204 ? 117.742 120.268 100.275 1.00 88.28  ? 204 SER D N     1 
ATOM   4820 C CA    . SER B 2 204 ? 117.962 120.018 98.862  1.00 88.28  ? 204 SER D CA    1 
ATOM   4821 C C     . SER B 2 204 ? 118.650 118.705 98.673  1.00 88.28  ? 204 SER D C     1 
ATOM   4822 O O     . SER B 2 204 ? 118.378 117.997 97.703  1.00 88.28  ? 204 SER D O     1 
ATOM   4823 C CB    . SER B 2 204 ? 118.755 121.123 98.220  1.00 118.91 ? 204 SER D CB    1 
ATOM   4824 O OG    . SER B 2 204 ? 118.010 122.307 98.203  1.00 118.91 ? 204 SER D OG    1 
ATOM   4825 N N     . ILE B 2 205 ? 119.494 118.316 99.602  1.00 86.79  ? 205 ILE D N     1 
ATOM   4826 C CA    . ILE B 2 205 ? 120.070 117.004 99.476  1.00 86.79  ? 205 ILE D CA    1 
ATOM   4827 C C     . ILE B 2 205 ? 118.967 115.978 99.522  1.00 86.79  ? 205 ILE D C     1 
ATOM   4828 O O     . ILE B 2 205 ? 118.907 115.067 98.695  1.00 86.79  ? 205 ILE D O     1 
ATOM   4829 C CB    . ILE B 2 205 ? 121.113 116.765 100.553 1.00 128.42 ? 205 ILE D CB    1 
ATOM   4830 C CG1   . ILE B 2 205 ? 122.277 117.698 100.345 1.00 128.42 ? 205 ILE D CG1   1 
ATOM   4831 C CG2   . ILE B 2 205 ? 121.563 115.293 100.520 1.00 128.42 ? 205 ILE D CG2   1 
ATOM   4832 C CD1   . ILE B 2 205 ? 123.266 117.757 101.489 1.00 128.42 ? 205 ILE D CD1   1 
ATOM   4833 N N     . TYR B 2 206 ? 118.055 116.143 100.463 1.00 88.84  ? 206 TYR D N     1 
ATOM   4834 C CA    . TYR B 2 206 ? 116.928 115.247 100.593 1.00 88.84  ? 206 TYR D CA    1 
ATOM   4835 C C     . TYR B 2 206 ? 116.104 115.218 99.334  1.00 88.84  ? 206 TYR D C     1 
ATOM   4836 O O     . TYR B 2 206 ? 115.770 114.141 98.843  1.00 88.84  ? 206 TYR D O     1 
ATOM   4837 C CB    . TYR B 2 206 ? 116.044 115.660 101.754 1.00 122.96 ? 206 TYR D CB    1 
ATOM   4838 C CG    . TYR B 2 206 ? 114.944 114.701 101.997 1.00 122.96 ? 206 TYR D CG    1 
ATOM   4839 C CD1   . TYR B 2 206 ? 113.763 114.812 101.337 1.00 122.96 ? 206 TYR D CD1   1 
ATOM   4840 C CD2   . TYR B 2 206 ? 115.101 113.697 102.871 1.00 122.96 ? 206 TYR D CD2   1 
ATOM   4841 C CE1   . TYR B 2 206 ? 112.771 113.924 101.545 1.00 122.96 ? 206 TYR D CE1   1 
ATOM   4842 C CE2   . TYR B 2 206 ? 114.129 112.812 103.089 1.00 122.96 ? 206 TYR D CE2   1 
ATOM   4843 C CZ    . TYR B 2 206 ? 112.961 112.918 102.429 1.00 122.96 ? 206 TYR D CZ    1 
ATOM   4844 O OH    . TYR B 2 206 ? 111.959 111.999 102.639 1.00 122.96 ? 206 TYR D OH    1 
ATOM   4845 N N     . ARG B 2 207 ? 115.743 116.377 98.810  1.00 89.07  ? 207 ARG D N     1 
ATOM   4846 C CA    . ARG B 2 207 ? 114.892 116.432 97.634  1.00 89.07  ? 207 ARG D CA    1 
ATOM   4847 C C     . ARG B 2 207 ? 115.522 115.735 96.466  1.00 89.07  ? 207 ARG D C     1 
ATOM   4848 O O     . ARG B 2 207 ? 114.830 115.052 95.714  1.00 89.07  ? 207 ARG D O     1 
ATOM   4849 C CB    . ARG B 2 207 ? 114.605 117.859 97.220  1.00 130.77 ? 207 ARG D CB    1 
ATOM   4850 C CG    . ARG B 2 207 ? 113.683 117.976 96.012  1.00 130.77 ? 207 ARG D CG    1 
ATOM   4851 C CD    . ARG B 2 207 ? 113.516 119.391 95.523  1.00 130.77 ? 207 ARG D CD    1 
ATOM   4852 N NE    . ARG B 2 207 ? 114.737 119.945 94.953  1.00 130.77 ? 207 ARG D NE    1 
ATOM   4853 C CZ    . ARG B 2 207 ? 115.195 119.682 93.730  1.00 130.77 ? 207 ARG D CZ    1 
ATOM   4854 N NH1   . ARG B 2 207 ? 114.565 118.865 92.913  1.00 130.77 ? 207 ARG D NH1   1 
ATOM   4855 N NH2   . ARG B 2 207 ? 116.325 120.243 93.316  1.00 130.77 ? 207 ARG D NH2   1 
ATOM   4856 N N     . ILE B 2 208 ? 116.819 115.945 96.250  1.00 87.56  ? 208 ILE D N     1 
ATOM   4857 C CA    . ILE B 2 208 ? 117.484 115.345 95.105  1.00 87.56  ? 208 ILE D CA    1 
ATOM   4858 C C     . ILE B 2 208 ? 117.469 113.849 95.235  1.00 87.56  ? 208 ILE D C     1 
ATOM   4859 O O     . ILE B 2 208 ? 117.157 113.143 94.280  1.00 87.56  ? 208 ILE D O     1 
ATOM   4860 C CB    . ILE B 2 208 ? 118.903 115.865 94.972  1.00 129.56 ? 208 ILE D CB    1 
ATOM   4861 C CG1   . ILE B 2 208 ? 118.859 117.323 94.634  1.00 129.56 ? 208 ILE D CG1   1 
ATOM   4862 C CG2   . ILE B 2 208 ? 119.629 115.092 93.916  1.00 129.56 ? 208 ILE D CG2   1 
ATOM   4863 C CD1   . ILE B 2 208 ? 120.140 118.052 94.812  1.00 129.56 ? 208 ILE D CD1   1 
ATOM   4864 N N     . VAL B 2 209 ? 117.786 113.334 96.419  1.00 87.41  ? 209 VAL D N     1 
ATOM   4865 C CA    . VAL B 2 209 ? 117.781 111.890 96.571  1.00 87.41  ? 209 VAL D CA    1 
ATOM   4866 C C     . VAL B 2 209 ? 116.390 111.325 96.441  1.00 87.41  ? 209 VAL D C     1 
ATOM   4867 O O     . VAL B 2 209 ? 116.193 110.250 95.872  1.00 87.41  ? 209 VAL D O     1 
ATOM   4868 C CB    . VAL B 2 209 ? 118.408 111.483 97.885  1.00 127.10 ? 209 VAL D CB    1 
ATOM   4869 C CG1   . VAL B 2 209 ? 118.218 109.990 98.065  1.00 127.10 ? 209 VAL D CG1   1 
ATOM   4870 C CG2   . VAL B 2 209 ? 119.851 111.827 97.834  1.00 127.10 ? 209 VAL D CG2   1 
ATOM   4871 N N     . ALA B 2 210 ? 115.418 111.977 97.013  1.00 87.03  ? 210 ALA D N     1 
ATOM   4872 C CA    . ALA B 2 210 ? 114.069 111.490 96.871  1.00 87.03  ? 210 ALA D CA    1 
ATOM   4873 C C     . ALA B 2 210 ? 113.639 111.512 95.418  1.00 87.03  ? 210 ALA D C     1 
ATOM   4874 O O     . ALA B 2 210 ? 112.974 110.591 94.951  1.00 87.03  ? 210 ALA D O     1 
ATOM   4875 C CB    . ALA B 2 210 ? 113.137 112.312 97.749  1.00 118.68 ? 210 ALA D CB    1 
ATOM   4876 N N     . THR B 2 211 ? 114.064 112.511 94.669  1.00 86.97  ? 211 THR D N     1 
ATOM   4877 C CA    . THR B 2 211 ? 113.715 112.607 93.260  1.00 86.97  ? 211 THR D CA    1 
ATOM   4878 C C     . THR B 2 211 ? 114.248 111.412 92.496  1.00 86.97  ? 211 THR D C     1 
ATOM   4879 O O     . THR B 2 211 ? 113.569 110.867 91.627  1.00 86.97  ? 211 THR D O     1 
ATOM   4880 C CB    . THR B 2 211 ? 114.266 113.904 92.666  1.00 121.74 ? 211 THR D CB    1 
ATOM   4881 O OG1   . THR B 2 211 ? 113.674 115.029 93.331  1.00 121.74 ? 211 THR D OG1   1 
ATOM   4882 C CG2   . THR B 2 211 ? 113.960 113.998 91.187  1.00 121.74 ? 211 THR D CG2   1 
ATOM   4883 N N     . GLN B 2 212 ? 115.445 110.967 92.844  1.00 89.30  ? 212 GLN D N     1 
ATOM   4884 C CA    . GLN B 2 212 ? 116.090 109.805 92.260  1.00 89.30  ? 212 GLN D CA    1 
ATOM   4885 C C     . GLN B 2 212 ? 115.378 108.502 92.579  1.00 89.30  ? 212 GLN D C     1 
ATOM   4886 O O     . GLN B 2 212 ? 115.728 107.470 92.018  1.00 89.30  ? 212 GLN D O     1 
ATOM   4887 C CB    . GLN B 2 212 ? 117.517 109.675 92.766  1.00 124.74 ? 212 GLN D CB    1 
ATOM   4888 C CG    . GLN B 2 212 ? 118.472 110.745 92.365  1.00 124.74 ? 212 GLN D CG    1 
ATOM   4889 C CD    . GLN B 2 212 ? 119.793 110.647 93.128  1.00 124.74 ? 212 GLN D CD    1 
ATOM   4890 O OE1   . GLN B 2 212 ? 119.872 110.037 94.197  1.00 124.74 ? 212 GLN D OE1   1 
ATOM   4891 N NE2   . GLN B 2 212 ? 120.826 111.257 92.586  1.00 124.74 ? 212 GLN D NE2   1 
ATOM   4892 N N     . GLY B 2 213 ? 114.431 108.508 93.503  1.00 89.21  ? 213 GLY D N     1 
ATOM   4893 C CA    . GLY B 2 213 ? 113.749 107.305 93.895  1.00 89.21  ? 213 GLY D CA    1 
ATOM   4894 C C     . GLY B 2 213 ? 114.429 106.563 95.001  1.00 89.21  ? 213 GLY D C     1 
ATOM   4895 O O     . GLY B 2 213 ? 114.210 105.365 95.147  1.00 89.21  ? 213 GLY D O     1 
ATOM   4896 N N     . LYS B 2 214 ? 115.269 107.218 95.773  1.00 88.97  ? 214 LYS D N     1 
ATOM   4897 C CA    . LYS B 2 214 ? 116.016 106.554 96.819  1.00 88.97  ? 214 LYS D CA    1 
ATOM   4898 C C     . LYS B 2 214 ? 115.703 107.105 98.202  1.00 88.97  ? 214 LYS D C     1 
ATOM   4899 O O     . LYS B 2 214 ? 116.551 107.052 99.090  1.00 88.97  ? 214 LYS D O     1 
ATOM   4900 C CB    . LYS B 2 214 ? 117.510 106.640 96.515  1.00 133.33 ? 214 LYS D CB    1 
ATOM   4901 C CG    . LYS B 2 214 ? 117.915 105.883 95.257  1.00 133.33 ? 214 LYS D CG    1 
ATOM   4902 C CD    . LYS B 2 214 ? 119.414 105.993 94.932  1.00 133.33 ? 214 LYS D CD    1 
ATOM   4903 C CE    . LYS B 2 214 ? 120.287 105.140 95.855  1.00 133.33 ? 214 LYS D CE    1 
ATOM   4904 N NZ    . LYS B 2 214 ? 120.060 103.673 95.665  1.00 133.33 ? 214 LYS D NZ    1 
ATOM   4905 N N     . GLU B 2 215 ? 114.499 107.638 98.428  1.00 90.08  ? 215 GLU D N     1 
ATOM   4906 C CA    . GLU B 2 215 ? 114.234 108.217 99.740  1.00 90.08  ? 215 GLU D CA    1 
ATOM   4907 C C     . GLU B 2 215 ? 114.235 107.182 100.833 1.00 90.08  ? 215 GLU D C     1 
ATOM   4908 O O     . GLU B 2 215 ? 114.561 107.501 101.973 1.00 90.08  ? 215 GLU D O     1 
ATOM   4909 C CB    . GLU B 2 215 ? 112.911 108.981 99.774  1.00 120.99 ? 215 GLU D CB    1 
ATOM   4910 C CG    . GLU B 2 215 ? 111.641 108.155 99.708  1.00 120.99 ? 215 GLU D CG    1 
ATOM   4911 C CD    . GLU B 2 215 ? 111.234 107.797 98.313  1.00 120.99 ? 215 GLU D CD    1 
ATOM   4912 O OE1   . GLU B 2 215 ? 112.092 107.761 97.435  1.00 120.99 ? 215 GLU D OE1   1 
ATOM   4913 O OE2   . GLU B 2 215 ? 110.048 107.545 98.090  1.00 120.99 ? 215 GLU D OE2   1 
ATOM   4914 N N     . ASN B 2 216 ? 113.952 105.943 100.509 1.00 87.28  ? 216 ASN D N     1 
ATOM   4915 C CA    . ASN B 2 216 ? 113.859 104.918 101.520 1.00 87.28  ? 216 ASN D CA    1 
ATOM   4916 C C     . ASN B 2 216 ? 115.211 104.420 101.950 1.00 87.28  ? 216 ASN D C     1 
ATOM   4917 O O     . ASN B 2 216 ? 115.296 103.578 102.848 1.00 87.28  ? 216 ASN D O     1 
ATOM   4918 C CB    . ASN B 2 216 ? 113.029 103.774 101.016 1.00 118.24 ? 216 ASN D CB    1 
ATOM   4919 C CG    . ASN B 2 216 ? 111.610 104.114 100.933 1.00 118.24 ? 216 ASN D CG    1 
ATOM   4920 O OD1   . ASN B 2 216 ? 111.008 104.545 101.922 1.00 118.24 ? 216 ASN D OD1   1 
ATOM   4921 N ND2   . ASN B 2 216 ? 111.044 103.968 99.765  1.00 118.24 ? 216 ASN D ND2   1 
ATOM   4922 N N     . GLU B 2 217 ? 116.269 104.909 101.325 1.00 89.40  ? 217 GLU D N     1 
ATOM   4923 C CA    . GLU B 2 217 ? 117.618 104.560 101.706 1.00 89.40  ? 217 GLU D CA    1 
ATOM   4924 C C     . GLU B 2 217 ? 118.255 105.665 102.514 1.00 89.40  ? 217 GLU D C     1 
ATOM   4925 O O     . GLU B 2 217 ? 119.347 105.484 103.028 1.00 89.40  ? 217 GLU D O     1 
ATOM   4926 C CB    . GLU B 2 217 ? 118.449 104.264 100.472 1.00 120.08 ? 217 GLU D CB    1 
ATOM   4927 C CG    . GLU B 2 217 ? 117.915 103.113 99.644  1.00 120.08 ? 217 GLU D CG    1 
ATOM   4928 C CD    . GLU B 2 217 ? 118.759 102.807 98.430  1.00 120.08 ? 217 GLU D CD    1 
ATOM   4929 O OE1   . GLU B 2 217 ? 119.973 102.639 98.584  1.00 120.08 ? 217 GLU D OE1   1 
ATOM   4930 O OE2   . GLU B 2 217 ? 118.209 102.746 97.321  1.00 120.08 ? 217 GLU D OE2   1 
ATOM   4931 N N     . LEU B 2 218 ? 117.596 106.803 102.633 1.00 87.66  ? 218 LEU D N     1 
ATOM   4932 C CA    . LEU B 2 218 ? 118.218 107.916 103.305 1.00 87.66  ? 218 LEU D CA    1 
ATOM   4933 C C     . LEU B 2 218 ? 118.355 107.655 104.771 1.00 87.66  ? 218 LEU D C     1 
ATOM   4934 O O     . LEU B 2 218 ? 117.436 107.193 105.452 1.00 87.66  ? 218 LEU D O     1 
ATOM   4935 C CB    . LEU B 2 218 ? 117.452 109.211 103.086 1.00 129.70 ? 218 LEU D CB    1 
ATOM   4936 C CG    . LEU B 2 218 ? 117.633 109.878 101.725 1.00 129.70 ? 218 LEU D CG    1 
ATOM   4937 C CD1   . LEU B 2 218 ? 116.653 111.007 101.570 1.00 129.70 ? 218 LEU D CD1   1 
ATOM   4938 C CD2   . LEU B 2 218 ? 119.049 110.434 101.594 1.00 129.70 ? 218 LEU D CD2   1 
ATOM   4939 N N     . SER B 2 219 ? 119.526 107.986 105.245 1.00 89.46  ? 219 SER D N     1 
ATOM   4940 C CA    . SER B 2 219 ? 119.906 107.865 106.619 1.00 89.46  ? 219 SER D CA    1 
ATOM   4941 C C     . SER B 2 219 ? 120.994 108.869 106.831 1.00 89.46  ? 219 SER D C     1 
ATOM   4942 O O     . SER B 2 219 ? 121.434 109.528 105.896 1.00 89.46  ? 219 SER D O     1 
ATOM   4943 C CB    . SER B 2 219 ? 120.394 106.471 106.919 1.00 120.49 ? 219 SER D CB    1 
ATOM   4944 O OG    . SER B 2 219 ? 121.643 106.281 106.314 1.00 120.49 ? 219 SER D OG    1 
ATOM   4945 N N     . GLU B 2 220 ? 121.452 108.962 108.056 1.00 90.90  ? 220 GLU D N     1 
ATOM   4946 C CA    . GLU B 2 220 ? 122.490 109.909 108.365 1.00 90.90  ? 220 GLU D CA    1 
ATOM   4947 C C     . GLU B 2 220 ? 123.704 109.689 107.498 1.00 90.90  ? 220 GLU D C     1 
ATOM   4948 O O     . GLU B 2 220 ? 124.328 110.654 107.061 1.00 90.90  ? 220 GLU D O     1 
ATOM   4949 C CB    . GLU B 2 220 ? 122.882 109.807 109.825 1.00 122.09 ? 220 GLU D CB    1 
ATOM   4950 C CG    . GLU B 2 220 ? 121.777 110.126 110.822 1.00 122.09 ? 220 GLU D CG    1 
ATOM   4951 C CD    . GLU B 2 220 ? 120.891 108.934 111.096 1.00 122.09 ? 220 GLU D CD    1 
ATOM   4952 O OE1   . GLU B 2 220 ? 121.015 107.937 110.383 1.00 122.09 ? 220 GLU D OE1   1 
ATOM   4953 O OE2   . GLU B 2 220 ? 120.091 108.977 112.029 1.00 122.09 ? 220 GLU D OE2   1 
ATOM   4954 N N     . SER B 2 221 ? 124.025 108.442 107.180 1.00 89.84  ? 221 SER D N     1 
ATOM   4955 C CA    . SER B 2 221 ? 125.236 108.187 106.423 1.00 89.84  ? 221 SER D CA    1 
ATOM   4956 C C     . SER B 2 221 ? 125.208 108.779 105.021 1.00 89.84  ? 221 SER D C     1 
ATOM   4957 O O     . SER B 2 221 ? 126.264 109.161 104.505 1.00 89.84  ? 221 SER D O     1 
ATOM   4958 C CB    . SER B 2 221 ? 125.498 106.707 106.342 1.00 121.01 ? 221 SER D CB    1 
ATOM   4959 O OG    . SER B 2 221 ? 124.508 106.073 105.562 1.00 121.01 ? 221 SER D OG    1 
ATOM   4960 N N     . ILE B 2 222 ? 124.052 108.887 104.385 1.00 91.21  ? 222 ILE D N     1 
ATOM   4961 C CA    . ILE B 2 222 ? 124.073 109.484 103.064 1.00 91.21  ? 222 ILE D CA    1 
ATOM   4962 C C     . ILE B 2 222 ? 124.255 110.963 103.186 1.00 91.21  ? 222 ILE D C     1 
ATOM   4963 O O     . ILE B 2 222 ? 125.011 111.567 102.420 1.00 91.21  ? 222 ILE D O     1 
ATOM   4964 C CB    . ILE B 2 222 ? 122.846 109.145 102.239 1.00 134.96 ? 222 ILE D CB    1 
ATOM   4965 C CG1   . ILE B 2 222 ? 122.912 107.669 101.916 1.00 134.96 ? 222 ILE D CG1   1 
ATOM   4966 C CG2   . ILE B 2 222 ? 122.806 110.006 100.961 1.00 134.96 ? 222 ILE D CG2   1 
ATOM   4967 C CD1   . ILE B 2 222 ? 121.660 107.090 101.282 1.00 134.96 ? 222 ILE D CD1   1 
ATOM   4968 N N     . PHE B 2 223 ? 123.584 111.572 104.138 1.00 89.73  ? 223 PHE D N     1 
ATOM   4969 C CA    . PHE B 2 223 ? 123.777 112.988 104.320 1.00 89.73  ? 223 PHE D CA    1 
ATOM   4970 C C     . PHE B 2 223 ? 125.201 113.301 104.695 1.00 89.73  ? 223 PHE D C     1 
ATOM   4971 O O     . PHE B 2 223 ? 125.778 114.261 104.180 1.00 89.73  ? 223 PHE D O     1 
ATOM   4972 C CB    . PHE B 2 223 ? 122.842 113.510 105.355 1.00 125.16 ? 223 PHE D CB    1 
ATOM   4973 C CG    . PHE B 2 223 ? 121.517 113.734 104.839 1.00 125.16 ? 223 PHE D CG    1 
ATOM   4974 C CD1   . PHE B 2 223 ? 121.201 114.899 104.242 1.00 125.16 ? 223 PHE D CD1   1 
ATOM   4975 C CD2   . PHE B 2 223 ? 120.569 112.772 104.938 1.00 125.16 ? 223 PHE D CD2   1 
ATOM   4976 C CE1   . PHE B 2 223 ? 119.975 115.112 103.774 1.00 125.16 ? 223 PHE D CE1   1 
ATOM   4977 C CE2   . PHE B 2 223 ? 119.330 112.987 104.454 1.00 125.16 ? 223 PHE D CE2   1 
ATOM   4978 C CZ    . PHE B 2 223 ? 119.042 114.166 103.874 1.00 125.16 ? 223 PHE D CZ    1 
ATOM   4979 N N     . ASP B 2 224 ? 125.800 112.495 105.544 1.00 90.36  ? 224 ASP D N     1 
ATOM   4980 C CA    . ASP B 2 224 ? 127.171 112.741 105.933 1.00 90.36  ? 224 ASP D CA    1 
ATOM   4981 C C     . ASP B 2 224 ? 128.114 112.595 104.752 1.00 90.36  ? 224 ASP D C     1 
ATOM   4982 O O     . ASP B 2 224 ? 129.061 113.373 104.628 1.00 90.36  ? 224 ASP D O     1 
ATOM   4983 C CB    . ASP B 2 224 ? 127.613 111.779 107.008 1.00 116.18 ? 224 ASP D CB    1 
ATOM   4984 C CG    . ASP B 2 224 ? 126.936 111.983 108.338 1.00 116.18 ? 224 ASP D CG    1 
ATOM   4985 O OD1   . ASP B 2 224 ? 126.373 113.044 108.612 1.00 116.18 ? 224 ASP D OD1   1 
ATOM   4986 O OD2   . ASP B 2 224 ? 126.986 111.035 109.124 1.00 116.18 ? 224 ASP D OD2   1 
ATOM   4987 N N     . GLN B 2 225 ? 127.886 111.616 103.872 1.00 87.87  ? 225 GLN D N     1 
ATOM   4988 C CA    . GLN B 2 225 ? 128.750 111.487 102.709 1.00 87.87  ? 225 GLN D CA    1 
ATOM   4989 C C     . GLN B 2 225 ? 128.627 112.675 101.781 1.00 87.87  ? 225 GLN D C     1 
ATOM   4990 O O     . GLN B 2 225 ? 129.642 113.165 101.272 1.00 87.87  ? 225 GLN D O     1 
ATOM   4991 C CB    . GLN B 2 225 ? 128.449 110.237 101.923 1.00 122.75 ? 225 GLN D CB    1 
ATOM   4992 C CG    . GLN B 2 225 ? 128.840 109.006 102.583 1.00 122.75 ? 225 GLN D CG    1 
ATOM   4993 C CD    . GLN B 2 225 ? 128.291 107.827 101.876 1.00 122.75 ? 225 GLN D CD    1 
ATOM   4994 O OE1   . GLN B 2 225 ? 127.469 107.976 100.978 1.00 122.75 ? 225 GLN D OE1   1 
ATOM   4995 N NE2   . GLN B 2 225 ? 128.711 106.636 102.279 1.00 122.75 ? 225 GLN D NE2   1 
ATOM   4996 N N     . VAL B 2 226 ? 127.413 113.164 101.541 1.00 87.43  ? 226 VAL D N     1 
ATOM   4997 C CA    . VAL B 2 226 ? 127.302 114.296 100.641 1.00 87.43  ? 226 VAL D CA    1 
ATOM   4998 C C     . VAL B 2 226 ? 127.946 115.519 101.241 1.00 87.43  ? 226 VAL D C     1 
ATOM   4999 O O     . VAL B 2 226 ? 128.666 116.250 100.559 1.00 87.43  ? 226 VAL D O     1 
ATOM   5000 C CB    . VAL B 2 226 ? 125.847 114.572 100.282 1.00 127.13 ? 226 VAL D CB    1 
ATOM   5001 C CG1   . VAL B 2 226 ? 125.743 115.867 99.480  1.00 127.13 ? 226 VAL D CG1   1 
ATOM   5002 C CG2   . VAL B 2 226 ? 125.292 113.441 99.535  1.00 127.13 ? 226 VAL D CG2   1 
ATOM   5003 N N     . LEU B 2 227 ? 127.701 115.769 102.502 1.00 87.09  ? 227 LEU D N     1 
ATOM   5004 C CA    . LEU B 2 227 ? 128.259 116.942 103.127 1.00 87.09  ? 227 LEU D CA    1 
ATOM   5005 C C     . LEU B 2 227 ? 129.770 116.849 103.181 1.00 87.09  ? 227 LEU D C     1 
ATOM   5006 O O     . LEU B 2 227 ? 130.475 117.826 102.915 1.00 87.09  ? 227 LEU D O     1 
ATOM   5007 C CB    . LEU B 2 227 ? 127.642 117.080 104.503 1.00 128.86 ? 227 LEU D CB    1 
ATOM   5008 C CG    . LEU B 2 227 ? 126.153 117.414 104.543 1.00 128.86 ? 227 LEU D CG    1 
ATOM   5009 C CD1   . LEU B 2 227 ? 125.595 117.201 105.909 1.00 128.86 ? 227 LEU D CD1   1 
ATOM   5010 C CD2   . LEU B 2 227 ? 125.953 118.823 104.158 1.00 128.86 ? 227 LEU D CD2   1 
ATOM   5011 N N     . ALA B 2 228 ? 130.300 115.683 103.488 1.00 87.03  ? 228 ALA D N     1 
ATOM   5012 C CA    . ALA B 2 228 ? 131.734 115.551 103.565 1.00 87.03  ? 228 ALA D CA    1 
ATOM   5013 C C     . ALA B 2 228 ? 132.370 115.729 102.219 1.00 87.03  ? 228 ALA D C     1 
ATOM   5014 O O     . ALA B 2 228 ? 133.417 116.361 102.118 1.00 87.03  ? 228 ALA D O     1 
ATOM   5015 C CB    . ALA B 2 228 ? 132.105 114.194 104.122 1.00 118.68 ? 228 ALA D CB    1 
ATOM   5016 N N     . LYS B 2 229 ? 131.757 115.211 101.160 1.00 89.79  ? 229 LYS D N     1 
ATOM   5017 C CA    . LYS B 2 229 ? 132.348 115.428 99.850  1.00 89.79  ? 229 LYS D CA    1 
ATOM   5018 C C     . LYS B 2 229 ? 132.348 116.893 99.513  1.00 89.79  ? 229 LYS D C     1 
ATOM   5019 O O     . LYS B 2 229 ? 133.328 117.403 98.980  1.00 89.79  ? 229 LYS D O     1 
ATOM   5020 C CB    . LYS B 2 229 ? 131.624 114.657 98.757  1.00 134.56 ? 229 LYS D CB    1 
ATOM   5021 C CG    . LYS B 2 229 ? 131.802 113.132 98.771  1.00 134.56 ? 229 LYS D CG    1 
ATOM   5022 C CD    . LYS B 2 229 ? 133.178 112.645 98.327  1.00 134.56 ? 229 LYS D CD    1 
ATOM   5023 C CE    . LYS B 2 229 ? 133.436 112.862 96.849  1.00 134.56 ? 229 LYS D CE    1 
ATOM   5024 N NZ    . LYS B 2 229 ? 134.681 112.164 96.387  1.00 134.56 ? 229 LYS D NZ    1 
ATOM   5025 N N     . ALA B 2 230 ? 131.279 117.601 99.838  1.00 89.55  ? 230 ALA D N     1 
ATOM   5026 C CA    . ALA B 2 230 ? 131.290 119.014 99.537  1.00 89.55  ? 230 ALA D CA    1 
ATOM   5027 C C     . ALA B 2 230 ? 132.455 119.683 100.210 1.00 89.55  ? 230 ALA D C     1 
ATOM   5028 O O     . ALA B 2 230 ? 133.162 120.464 99.585  1.00 89.55  ? 230 ALA D O     1 
ATOM   5029 C CB    . ALA B 2 230 ? 129.980 119.652 99.955  1.00 122.11 ? 230 ALA D CB    1 
ATOM   5030 N N     . LEU B 2 231 ? 132.705 119.379 101.467 1.00 89.11  ? 231 LEU D N     1 
ATOM   5031 C CA    . LEU B 2 231 ? 133.838 120.021 102.115 1.00 89.11  ? 231 LEU D CA    1 
ATOM   5032 C C     . LEU B 2 231 ? 135.125 119.680 101.424 1.00 89.11  ? 231 LEU D C     1 
ATOM   5033 O O     . LEU B 2 231 ? 136.000 120.536 101.277 1.00 89.11  ? 231 LEU D O     1 
ATOM   5034 C CB    . LEU B 2 231 ? 133.963 119.613 103.564 1.00 131.85 ? 231 LEU D CB    1 
ATOM   5035 C CG    . LEU B 2 231 ? 133.017 120.165 104.581 1.00 131.85 ? 231 LEU D CG    1 
ATOM   5036 C CD1   . LEU B 2 231 ? 133.150 119.362 105.855 1.00 131.85 ? 231 LEU D CD1   1 
ATOM   5037 C CD2   . LEU B 2 231 ? 133.407 121.581 104.852 1.00 131.85 ? 231 LEU D CD2   1 
ATOM   5038 N N     . VAL B 2 232 ? 135.276 118.432 101.020 1.00 90.14  ? 232 VAL D N     1 
ATOM   5039 C CA    . VAL B 2 232 ? 136.521 118.019 100.400 1.00 90.14  ? 232 VAL D CA    1 
ATOM   5040 C C     . VAL B 2 232 ? 136.742 118.747 99.099  1.00 90.14  ? 232 VAL D C     1 
ATOM   5041 O O     . VAL B 2 232 ? 137.846 119.228 98.834  1.00 90.14  ? 232 VAL D O     1 
ATOM   5042 C CB    . VAL B 2 232 ? 136.545 116.510 100.184 1.00 131.07 ? 232 VAL D CB    1 
ATOM   5043 C CG1   . VAL B 2 232 ? 137.746 116.104 99.390  1.00 131.07 ? 232 VAL D CG1   1 
ATOM   5044 C CG2   . VAL B 2 232 ? 136.600 115.826 101.512 1.00 131.07 ? 232 VAL D CG2   1 
ATOM   5045 N N     . GLU B 2 233 ? 135.716 118.835 98.266  1.00 91.86  ? 233 GLU D N     1 
ATOM   5046 C CA    . GLU B 2 233 ? 135.890 119.463 96.969  1.00 91.86  ? 233 GLU D CA    1 
ATOM   5047 C C     . GLU B 2 233 ? 136.083 120.963 97.085  1.00 91.86  ? 233 GLU D C     1 
ATOM   5048 O O     . GLU B 2 233 ? 136.869 121.546 96.340  1.00 91.86  ? 233 GLU D O     1 
ATOM   5049 C CB    . GLU B 2 233 ? 134.706 119.171 96.079  1.00 123.38 ? 233 GLU D CB    1 
ATOM   5050 C CG    . GLU B 2 233 ? 134.543 117.751 95.665  1.00 123.38 ? 233 GLU D CG    1 
ATOM   5051 C CD    . GLU B 2 233 ? 135.719 117.223 94.937  1.00 123.38 ? 233 GLU D CD    1 
ATOM   5052 O OE1   . GLU B 2 233 ? 136.402 117.998 94.270  1.00 123.38 ? 233 GLU D OE1   1 
ATOM   5053 O OE2   . GLU B 2 233 ? 135.972 116.021 95.032  1.00 123.38 ? 233 GLU D OE2   1 
ATOM   5054 N N     . ILE B 2 234 ? 135.375 121.604 98.000  1.00 88.86  ? 234 ILE D N     1 
ATOM   5055 C CA    . ILE B 2 234 ? 135.514 123.040 98.183  1.00 88.86  ? 234 ILE D CA    1 
ATOM   5056 C C     . ILE B 2 234 ? 136.889 123.368 98.637  1.00 88.86  ? 234 ILE D C     1 
ATOM   5057 O O     . ILE B 2 234 ? 137.501 124.323 98.174  1.00 88.86  ? 234 ILE D O     1 
ATOM   5058 C CB    . ILE B 2 234 ? 134.503 123.542 99.198  1.00 131.48 ? 234 ILE D CB    1 
ATOM   5059 C CG1   . ILE B 2 234 ? 133.097 123.379 98.630  1.00 131.48 ? 234 ILE D CG1   1 
ATOM   5060 C CG2   . ILE B 2 234 ? 134.817 124.991 99.550  1.00 131.48 ? 234 ILE D CG2   1 
ATOM   5061 C CD1   . ILE B 2 234 ? 131.979 123.499 99.641  1.00 131.48 ? 234 ILE D CD1   1 
ATOM   5062 N N     . THR B 2 235 ? 137.399 122.564 99.534  1.00 89.36  ? 235 THR D N     1 
ATOM   5063 C CA    . THR B 2 235 ? 138.699 122.750 100.108 1.00 89.36  ? 235 THR D CA    1 
ATOM   5064 C C     . THR B 2 235 ? 139.800 122.263 99.189  1.00 89.36  ? 235 THR D C     1 
ATOM   5065 O O     . THR B 2 235 ? 140.938 122.700 99.329  1.00 89.36  ? 235 THR D O     1 
ATOM   5066 C CB    . THR B 2 235 ? 138.735 122.030 101.444 1.00 125.09 ? 235 THR D CB    1 
ATOM   5067 O OG1   . THR B 2 235 ? 137.638 122.469 102.259 1.00 125.09 ? 235 THR D OG1   1 
ATOM   5068 C CG2   . THR B 2 235 ? 139.966 122.318 102.166 1.00 125.09 ? 235 THR D CG2   1 
ATOM   5069 N N     . ALA B 2 236 ? 139.469 121.446 98.198  1.00 90.85  ? 236 ALA D N     1 
ATOM   5070 C CA    . ALA B 2 236 ? 140.463 120.808 97.338  1.00 90.85  ? 236 ALA D CA    1 
ATOM   5071 C C     . ALA B 2 236 ? 141.389 121.773 96.638  1.00 90.85  ? 236 ALA D C     1 
ATOM   5072 O O     . ALA B 2 236 ? 142.549 121.436 96.421  1.00 90.85  ? 236 ALA D O     1 
ATOM   5073 C CB    . ALA B 2 236 ? 139.784 119.961 96.280  1.00 123.89 ? 236 ALA D CB    1 
ATOM   5074 N N     . THR B 2 237 ? 140.931 122.941 96.251  1.00 92.30  ? 237 THR D N     1 
ATOM   5075 C CA    . THR B 2 237 ? 141.853 123.775 95.530  1.00 92.30  ? 237 THR D CA    1 
ATOM   5076 C C     . THR B 2 237 ? 142.934 124.336 96.431  1.00 92.30  ? 237 THR D C     1 
ATOM   5077 O O     . THR B 2 237 ? 143.921 124.864 95.934  1.00 92.30  ? 237 THR D O     1 
ATOM   5078 C CB    . THR B 2 237 ? 141.122 124.888 94.817  1.00 129.20 ? 237 THR D CB    1 
ATOM   5079 O OG1   . THR B 2 237 ? 140.394 125.675 95.753  1.00 129.20 ? 237 THR D OG1   1 
ATOM   5080 C CG2   . THR B 2 237 ? 140.166 124.324 93.816  1.00 129.20 ? 237 THR D CG2   1 
ATOM   5081 N N     . LEU B 2 238 ? 142.798 124.199 97.734  1.00 90.67  ? 238 LEU D N     1 
ATOM   5082 C CA    . LEU B 2 238 ? 143.801 124.653 98.679  1.00 90.67  ? 238 LEU D CA    1 
ATOM   5083 C C     . LEU B 2 238 ? 144.807 123.576 98.959  1.00 90.67  ? 238 LEU D C     1 
ATOM   5084 O O     . LEU B 2 238 ? 145.710 123.802 99.760  1.00 90.67  ? 238 LEU D O     1 
ATOM   5085 C CB    . LEU B 2 238 ? 143.158 125.052 100.006 1.00 134.16 ? 238 LEU D CB    1 
ATOM   5086 C CG    . LEU B 2 238 ? 142.067 126.115 100.025 1.00 134.16 ? 238 LEU D CG    1 
ATOM   5087 C CD1   . LEU B 2 238 ? 141.489 126.238 101.409 1.00 134.16 ? 238 LEU D CD1   1 
ATOM   5088 C CD2   . LEU B 2 238 ? 142.623 127.447 99.564  1.00 134.16 ? 238 LEU D CD2   1 
ATOM   5089 N N     . ARG B 2 239 ? 144.640 122.385 98.385  1.00 89.36  ? 239 ARG D N     1 
ATOM   5090 C CA    . ARG B 2 239 ? 145.533 121.273 98.659  1.00 89.36  ? 239 ARG D CA    1 
ATOM   5091 C C     . ARG B 2 239 ? 146.433 120.893 97.505  1.00 89.36  ? 239 ARG D C     1 
ATOM   5092 O O     . ARG B 2 239 ? 147.190 119.935 97.620  1.00 89.36  ? 239 ARG D O     1 
ATOM   5093 C CB    . ARG B 2 239 ? 144.735 120.069 99.087  1.00 131.19 ? 239 ARG D CB    1 
ATOM   5094 C CG    . ARG B 2 239 ? 144.001 120.302 100.339 1.00 131.19 ? 239 ARG D CG    1 
ATOM   5095 C CD    . ARG B 2 239 ? 143.556 119.071 100.961 1.00 131.19 ? 239 ARG D CD    1 
ATOM   5096 N NE    . ARG B 2 239 ? 142.690 118.329 100.100 1.00 131.19 ? 239 ARG D NE    1 
ATOM   5097 C CZ    . ARG B 2 239 ? 141.403 118.522 100.021 1.00 131.19 ? 239 ARG D CZ    1 
ATOM   5098 N NH1   . ARG B 2 239 ? 140.801 119.437 100.732 1.00 131.19 ? 239 ARG D NH1   1 
ATOM   5099 N NH2   . ARG B 2 239 ? 140.703 117.787 99.196  1.00 131.19 ? 239 ARG D NH2   1 
ATOM   5100 N N     . PHE B 2 240 ? 146.403 121.610 96.416  1.00 88.11  ? 240 PHE D N     1 
ATOM   5101 C CA    . PHE B 2 240 ? 147.225 121.289 95.275  1.00 88.11  ? 240 PHE D CA    1 
ATOM   5102 C C     . PHE B 2 240 ? 147.634 122.584 94.607  1.00 88.11  ? 240 PHE D C     1 
ATOM   5103 O O     . PHE B 2 240 ? 147.191 123.665 94.987  1.00 88.11  ? 240 PHE D O     1 
ATOM   5104 C CB    . PHE B 2 240 ? 146.486 120.430 94.292  1.00 122.90 ? 240 PHE D CB    1 
ATOM   5105 C CG    . PHE B 2 240 ? 146.078 119.102 94.805  1.00 122.90 ? 240 PHE D CG    1 
ATOM   5106 C CD1   . PHE B 2 240 ? 146.886 118.024 94.651  1.00 122.90 ? 240 PHE D CD1   1 
ATOM   5107 C CD2   . PHE B 2 240 ? 144.869 118.919 95.369  1.00 122.90 ? 240 PHE D CD2   1 
ATOM   5108 C CE1   . PHE B 2 240 ? 146.509 116.816 95.072  1.00 122.90 ? 240 PHE D CE1   1 
ATOM   5109 C CE2   . PHE B 2 240 ? 144.496 117.693 95.808  1.00 122.90 ? 240 PHE D CE2   1 
ATOM   5110 C CZ    . PHE B 2 240 ? 145.324 116.652 95.658  1.00 122.90 ? 240 PHE D CZ    1 
ATOM   5111 N N     . ASN B 2 241 ? 148.406 122.492 93.551  1.00 87.57  ? 241 ASN D N     1 
ATOM   5112 C CA    . ASN B 2 241 ? 148.843 123.711 92.904  1.00 87.57  ? 241 ASN D CA    1 
ATOM   5113 C C     . ASN B 2 241 ? 147.822 124.192 91.890  1.00 87.57  ? 241 ASN D C     1 
ATOM   5114 O O     . ASN B 2 241 ? 148.016 124.164 90.682  1.00 87.57  ? 241 ASN D O     1 
ATOM   5115 C CB    . ASN B 2 241 ? 150.195 123.492 92.303  1.00 118.63 ? 241 ASN D CB    1 
ATOM   5116 C CG    . ASN B 2 241 ? 151.181 123.211 93.350  1.00 118.63 ? 241 ASN D CG    1 
ATOM   5117 O OD1   . ASN B 2 241 ? 151.140 123.800 94.418  1.00 118.63 ? 241 ASN D OD1   1 
ATOM   5118 N ND2   . ASN B 2 241 ? 152.067 122.285 93.081  1.00 118.63 ? 241 ASN D ND2   1 
ATOM   5119 N N     . SER B 2 242 ? 146.738 124.661 92.434  1.00 93.83  ? 242 SER D N     1 
ATOM   5120 C CA    . SER B 2 242 ? 145.593 125.121 91.691  1.00 93.83  ? 242 SER D CA    1 
ATOM   5121 C C     . SER B 2 242 ? 145.863 126.456 91.021  1.00 93.83  ? 242 SER D C     1 
ATOM   5122 O O     . SER B 2 242 ? 146.601 127.269 91.555  1.00 93.83  ? 242 SER D O     1 
ATOM   5123 C CB    . SER B 2 242 ? 144.420 125.295 92.643  1.00 126.38 ? 242 SER D CB    1 
ATOM   5124 O OG    . SER B 2 242 ? 143.310 125.875 91.983  1.00 126.38 ? 242 SER D OG    1 
ATOM   5125 N N     . PRO B 2 243 ? 145.275 126.689 89.855  1.00 95.10  ? 243 PRO D N     1 
ATOM   5126 C CA    . PRO B 2 243 ? 145.264 127.985 89.191  1.00 95.10  ? 243 PRO D CA    1 
ATOM   5127 C C     . PRO B 2 243 ? 144.155 128.962 89.627  1.00 95.10  ? 243 PRO D C     1 
ATOM   5128 O O     . PRO B 2 243 ? 144.177 130.114 89.180  1.00 95.10  ? 243 PRO D O     1 
ATOM   5129 C CB    . PRO B 2 243 ? 145.062 127.572 87.751  1.00 296.62 ? 243 PRO D CB    1 
ATOM   5130 C CG    . PRO B 2 243 ? 144.251 126.340 87.862  1.00 296.62 ? 243 PRO D CG    1 
ATOM   5131 C CD    . PRO B 2 243 ? 144.740 125.627 89.032  1.00 296.62 ? 243 PRO D CD    1 
ATOM   5132 N N     . LEU B 2 244 ? 143.166 128.570 90.435  1.00 94.62  ? 244 LEU D N     1 
ATOM   5133 C CA    . LEU B 2 244 ? 142.029 129.458 90.733  1.00 94.62  ? 244 LEU D CA    1 
ATOM   5134 C C     . LEU B 2 244 ? 142.027 130.073 92.109  1.00 94.62  ? 244 LEU D C     1 
ATOM   5135 O O     . LEU B 2 244 ? 141.807 131.267 92.249  1.00 94.62  ? 244 LEU D O     1 
ATOM   5136 C CB    . LEU B 2 244 ? 140.709 128.732 90.642  1.00 140.00 ? 244 LEU D CB    1 
ATOM   5137 C CG    . LEU B 2 244 ? 140.265 128.220 89.312  1.00 140.00 ? 244 LEU D CG    1 
ATOM   5138 C CD1   . LEU B 2 244 ? 139.019 127.388 89.520  1.00 140.00 ? 244 LEU D CD1   1 
ATOM   5139 C CD2   . LEU B 2 244 ? 139.963 129.377 88.382  1.00 140.00 ? 244 LEU D CD2   1 
ATOM   5140 N N     . ASN B 2 245 ? 142.170 129.264 93.122  1.00 92.85  ? 245 ASN D N     1 
ATOM   5141 C CA    . ASN B 2 245 ? 142.094 129.721 94.489  1.00 92.85  ? 245 ASN D CA    1 
ATOM   5142 C C     . ASN B 2 245 ? 143.199 129.033 95.241  1.00 92.85  ? 245 ASN D C     1 
ATOM   5143 O O     . ASN B 2 245 ? 143.008 127.948 95.762  1.00 92.85  ? 245 ASN D O     1 
ATOM   5144 C CB    . ASN B 2 245 ? 140.765 129.388 95.084  1.00 125.79 ? 245 ASN D CB    1 
ATOM   5145 C CG    . ASN B 2 245 ? 139.662 130.146 94.464  1.00 125.79 ? 245 ASN D CG    1 
ATOM   5146 O OD1   . ASN B 2 245 ? 139.541 131.357 94.649  1.00 125.79 ? 245 ASN D OD1   1 
ATOM   5147 N ND2   . ASN B 2 245 ? 138.815 129.457 93.747  1.00 125.79 ? 245 ASN D ND2   1 
ATOM   5148 N N     . ARG B 2 246 ? 144.335 129.656 95.304  1.00 90.02  ? 246 ARG D N     1 
ATOM   5149 C CA    . ARG B 2 246 ? 145.443 129.009 95.958  1.00 90.02  ? 246 ARG D CA    1 
ATOM   5150 C C     . ARG B 2 246 ? 145.447 129.267 97.440  1.00 90.02  ? 246 ARG D C     1 
ATOM   5151 O O     . ARG B 2 246 ? 146.309 128.744 98.160  1.00 90.02  ? 246 ARG D O     1 
ATOM   5152 C CB    . ARG B 2 246 ? 146.730 129.515 95.363  1.00 132.16 ? 246 ARG D CB    1 
ATOM   5153 C CG    . ARG B 2 246 ? 146.912 129.142 93.958  1.00 132.16 ? 246 ARG D CG    1 
ATOM   5154 C CD    . ARG B 2 246 ? 148.133 129.773 93.401  1.00 132.16 ? 246 ARG D CD    1 
ATOM   5155 N NE    . ARG B 2 246 ? 148.337 129.362 92.017  1.00 132.16 ? 246 ARG D NE    1 
ATOM   5156 C CZ    . ARG B 2 246 ? 149.292 129.837 91.223  1.00 132.16 ? 246 ARG D CZ    1 
ATOM   5157 N NH1   . ARG B 2 246 ? 150.142 130.757 91.645  1.00 132.16 ? 246 ARG D NH1   1 
ATOM   5158 N NH2   . ARG B 2 246 ? 149.398 129.377 89.977  1.00 132.16 ? 246 ARG D NH2   1 
ATOM   5159 N N     . SER B 2 247 ? 144.522 130.091 97.899  1.00 93.14  ? 247 SER D N     1 
ATOM   5160 C CA    . SER B 2 247 ? 144.478 130.493 99.290  1.00 93.14  ? 247 SER D CA    1 
ATOM   5161 C C     . SER B 2 247 ? 143.116 130.999 99.668  1.00 93.14  ? 247 SER D C     1 
ATOM   5162 O O     . SER B 2 247 ? 142.421 131.588 98.847  1.00 93.14  ? 247 SER D O     1 
ATOM   5163 C CB    . SER B 2 247 ? 145.461 131.592 99.571  1.00 125.45 ? 247 SER D CB    1 
ATOM   5164 O OG    . SER B 2 247 ? 145.273 132.068 100.884 1.00 125.45 ? 247 SER D OG    1 
ATOM   5165 N N     . MET B 2 248 ? 142.781 130.846 100.941 1.00 92.45  ? 248 MET D N     1 
ATOM   5166 C CA    . MET B 2 248 ? 141.550 131.414 101.433 1.00 92.45  ? 248 MET D CA    1 
ATOM   5167 C C     . MET B 2 248 ? 141.552 132.911 101.239 1.00 92.45  ? 248 MET D C     1 
ATOM   5168 O O     . MET B 2 248 ? 140.486 133.533 101.110 1.00 92.45  ? 248 MET D O     1 
ATOM   5169 C CB    . MET B 2 248 ? 141.379 131.058 102.890 1.00 132.77 ? 248 MET D CB    1 
ATOM   5170 C CG    . MET B 2 248 ? 141.036 129.656 103.113 1.00 132.77 ? 248 MET D CG    1 
ATOM   5171 S SD    . MET B 2 248 ? 141.083 129.192 104.816 1.00 132.77 ? 248 MET D SD    1 
ATOM   5172 C CE    . MET B 2 248 ? 139.652 130.011 105.447 1.00 132.77 ? 248 MET D CE    1 
ATOM   5173 N N     . MET B 2 249 ? 142.740 133.501 101.178 1.00 91.63  ? 249 MET D N     1 
ATOM   5174 C CA    . MET B 2 249 ? 142.849 134.921 100.916 1.00 91.63  ? 249 MET D CA    1 
ATOM   5175 C C     . MET B 2 249 ? 142.380 135.246 99.505  1.00 91.63  ? 249 MET D C     1 
ATOM   5176 O O     . MET B 2 249 ? 141.773 136.305 99.251  1.00 91.63  ? 249 MET D O     1 
ATOM   5177 C CB    . MET B 2 249 ? 144.282 135.352 101.133 1.00 131.59 ? 249 MET D CB    1 
ATOM   5178 C CG    . MET B 2 249 ? 144.479 136.819 101.158 1.00 131.59 ? 249 MET D CG    1 
ATOM   5179 S SD    . MET B 2 249 ? 143.571 137.618 102.477 1.00 131.59 ? 249 MET D SD    1 
ATOM   5180 C CE    . MET B 2 249 ? 144.537 137.195 103.926 1.00 131.59 ? 249 MET D CE    1 
ATOM   5181 N N     . GLU B 2 250 ? 142.620 134.332 98.572  1.00 90.41  ? 250 GLU D N     1 
ATOM   5182 C CA    . GLU B 2 250 ? 142.190 134.548 97.214  1.00 90.41  ? 250 GLU D CA    1 
ATOM   5183 C C     . GLU B 2 250 ? 140.728 134.254 97.097  1.00 90.41  ? 250 GLU D C     1 
ATOM   5184 O O     . GLU B 2 250 ? 140.030 134.928 96.343  1.00 90.41  ? 250 GLU D O     1 
ATOM   5185 C CB    . GLU B 2 250 ? 142.985 133.680 96.244  1.00 121.43 ? 250 GLU D CB    1 
ATOM   5186 C CG    . GLU B 2 250 ? 144.460 133.997 96.182  1.00 121.43 ? 250 GLU D CG    1 
ATOM   5187 C CD    . GLU B 2 250 ? 145.209 133.142 95.185  1.00 121.43 ? 250 GLU D CD    1 
ATOM   5188 O OE1   . GLU B 2 250 ? 144.573 132.363 94.472  1.00 121.43 ? 250 GLU D OE1   1 
ATOM   5189 O OE2   . GLU B 2 250 ? 146.435 133.249 95.120  1.00 121.43 ? 250 GLU D OE2   1 
ATOM   5190 N N     . MET B 2 251 ? 140.249 133.274 97.850  1.00 90.23  ? 251 MET D N     1 
ATOM   5191 C CA    . MET B 2 251 ? 138.842 132.970 97.802  1.00 90.23  ? 251 MET D CA    1 
ATOM   5192 C C     . MET B 2 251 ? 138.061 134.181 98.220  1.00 90.23  ? 251 MET D C     1 
ATOM   5193 O O     . MET B 2 251 ? 137.113 134.579 97.549  1.00 90.23  ? 251 MET D O     1 
ATOM   5194 C CB    . MET B 2 251 ? 138.496 131.805 98.704  1.00 129.58 ? 251 MET D CB    1 
ATOM   5195 C CG    . MET B 2 251 ? 138.983 130.496 98.242  1.00 129.58 ? 251 MET D CG    1 
ATOM   5196 S SD    . MET B 2 251 ? 138.600 129.165 99.376  1.00 129.58 ? 251 MET D SD    1 
ATOM   5197 C CE    . MET B 2 251 ? 136.850 128.948 99.168  1.00 129.58 ? 251 MET D CE    1 
ATOM   5198 N N     . SER B 2 252 ? 138.500 134.839 99.270  1.00 89.83  ? 252 SER D N     1 
ATOM   5199 C CA    . SER B 2 252 ? 137.794 136.025 99.687  1.00 89.83  ? 252 SER D CA    1 
ATOM   5200 C C     . SER B 2 252 ? 137.737 137.012 98.554  1.00 89.83  ? 252 SER D C     1 
ATOM   5201 O O     . SER B 2 252 ? 136.663 137.521 98.217  1.00 89.83  ? 252 SER D O     1 
ATOM   5202 C CB    . SER B 2 252 ? 138.470 136.625 100.888 1.00 120.99 ? 252 SER D CB    1 
ATOM   5203 O OG    . SER B 2 252 ? 137.800 137.775 101.324 1.00 120.99 ? 252 SER D OG    1 
ATOM   5204 N N     . THR B 2 253 ? 138.868 137.242 97.892  1.00 89.52  ? 253 THR D N     1 
ATOM   5205 C CA    . THR B 2 253 ? 138.856 138.193 96.783  1.00 89.52  ? 253 THR D CA    1 
ATOM   5206 C C     . THR B 2 253 ? 137.928 137.779 95.635  1.00 89.52  ? 253 THR D C     1 
ATOM   5207 O O     . THR B 2 253 ? 137.211 138.607 95.081  1.00 89.52  ? 253 THR D O     1 
ATOM   5208 C CB    . THR B 2 253 ? 140.259 138.383 96.258  1.00 125.31 ? 253 THR D CB    1 
ATOM   5209 O OG1   . THR B 2 253 ? 141.084 138.930 97.290  1.00 125.31 ? 253 THR D OG1   1 
ATOM   5210 C CG2   . THR B 2 253 ? 140.250 139.318 95.077  1.00 125.31 ? 253 THR D CG2   1 
ATOM   5211 N N     . ASN B 2 254 ? 137.943 136.513 95.256  1.00 88.58  ? 254 ASN D N     1 
ATOM   5212 C CA    . ASN B 2 254 ? 137.177 136.033 94.111  1.00 88.58  ? 254 ASN D CA    1 
ATOM   5213 C C     . ASN B 2 254 ? 135.693 135.873 94.386  1.00 88.58  ? 254 ASN D C     1 
ATOM   5214 O O     . ASN B 2 254 ? 134.883 136.024 93.473  1.00 88.58  ? 254 ASN D O     1 
ATOM   5215 C CB    . ASN B 2 254 ? 137.718 134.695 93.660  1.00 120.00 ? 254 ASN D CB    1 
ATOM   5216 C CG    . ASN B 2 254 ? 139.010 134.807 92.969  1.00 120.00 ? 254 ASN D CG    1 
ATOM   5217 O OD1   . ASN B 2 254 ? 139.308 135.824 92.355  1.00 120.00 ? 254 ASN D OD1   1 
ATOM   5218 N ND2   . ASN B 2 254 ? 139.795 133.777 93.040  1.00 120.00 ? 254 ASN D ND2   1 
ATOM   5219 N N     . LEU B 2 255 ? 135.319 135.528 95.591  1.00 85.97  ? 255 LEU D N     1 
ATOM   5220 C CA    . LEU B 2 255 ? 133.949 135.209 95.878  1.00 85.97  ? 255 LEU D CA    1 
ATOM   5221 C C     . LEU B 2 255 ? 133.141 136.322 96.530  1.00 85.97  ? 255 LEU D C     1 
ATOM   5222 O O     . LEU B 2 255 ? 131.921 136.338 96.346  1.00 85.97  ? 255 LEU D O     1 
ATOM   5223 C CB    . LEU B 2 255 ? 133.919 133.988 96.754  1.00 127.20 ? 255 LEU D CB    1 
ATOM   5224 C CG    . LEU B 2 255 ? 134.574 132.769 96.169  1.00 127.20 ? 255 LEU D CG    1 
ATOM   5225 C CD1   . LEU B 2 255 ? 134.657 131.693 97.200  1.00 127.20 ? 255 LEU D CD1   1 
ATOM   5226 C CD2   . LEU B 2 255 ? 133.827 132.285 94.983  1.00 127.20 ? 255 LEU D CD2   1 
ATOM   5227 N N     . VAL B 2 256 ? 133.726 137.237 97.296  1.00 82.68  ? 256 VAL D N     1 
ATOM   5228 C CA    . VAL B 2 256 ? 132.910 138.240 97.977  1.00 82.68  ? 256 VAL D CA    1 
ATOM   5229 C C     . VAL B 2 256 ? 133.381 139.670 97.757  1.00 82.68  ? 256 VAL D C     1 
ATOM   5230 O O     . VAL B 2 256 ? 134.094 140.209 98.599  1.00 82.68  ? 256 VAL D O     1 
ATOM   5231 C CB    . VAL B 2 256 ? 132.903 137.994 99.478  1.00 120.22 ? 256 VAL D CB    1 
ATOM   5232 C CG1   . VAL B 2 256 ? 131.918 138.983 100.148 1.00 120.22 ? 256 VAL D CG1   1 
ATOM   5233 C CG2   . VAL B 2 256 ? 132.585 136.550 99.781  1.00 120.22 ? 256 VAL D CG2   1 
ATOM   5234 N N     . PRO B 2 257 ? 132.973 140.323 96.689  1.00 84.99  ? 257 PRO D N     1 
ATOM   5235 C CA    . PRO B 2 257 ? 133.406 141.686 96.380  1.00 84.99  ? 257 PRO D CA    1 
ATOM   5236 C C     . PRO B 2 257 ? 132.734 142.772 97.209  1.00 84.99  ? 257 PRO D C     1 
ATOM   5237 O O     . PRO B 2 257 ? 133.200 143.921 97.214  1.00 84.99  ? 257 PRO D O     1 
ATOM   5238 C CB    . PRO B 2 257 ? 133.025 141.809 94.917  1.00 265.09 ? 257 PRO D CB    1 
ATOM   5239 C CG    . PRO B 2 257 ? 131.926 140.842 94.757  1.00 265.09 ? 257 PRO D CG    1 
ATOM   5240 C CD    . PRO B 2 257 ? 132.192 139.714 95.648  1.00 265.09 ? 257 PRO D CD    1 
ATOM   5241 N N     . PHE B 2 258 ? 131.644 142.451 97.886  1.00 86.82  ? 258 PHE D N     1 
ATOM   5242 C CA    . PHE B 2 258 ? 130.879 143.397 98.692  1.00 86.82  ? 258 PHE D CA    1 
ATOM   5243 C C     . PHE B 2 258 ? 130.712 142.788 100.073 1.00 86.82  ? 258 PHE D C     1 
ATOM   5244 O O     . PHE B 2 258 ? 129.640 142.253 100.372 1.00 86.82  ? 258 PHE D O     1 
ATOM   5245 C CB    . PHE B 2 258 ? 129.509 143.684 98.078  1.00 121.10 ? 258 PHE D CB    1 
ATOM   5246 C CG    . PHE B 2 258 ? 129.571 144.232 96.697  1.00 121.10 ? 258 PHE D CG    1 
ATOM   5247 C CD1   . PHE B 2 258 ? 129.891 145.546 96.470  1.00 121.10 ? 258 PHE D CD1   1 
ATOM   5248 C CD2   . PHE B 2 258 ? 129.330 143.420 95.610  1.00 121.10 ? 258 PHE D CD2   1 
ATOM   5249 C CE1   . PHE B 2 258 ? 129.971 146.044 95.189  1.00 121.10 ? 258 PHE D CE1   1 
ATOM   5250 C CE2   . PHE B 2 258 ? 129.404 143.912 94.327  1.00 121.10 ? 258 PHE D CE2   1 
ATOM   5251 C CZ    . PHE B 2 258 ? 129.726 145.230 94.120  1.00 121.10 ? 258 PHE D CZ    1 
ATOM   5252 N N     . PRO B 2 259 ? 131.682 142.998 100.973 1.00 81.30  ? 259 PRO D N     1 
ATOM   5253 C CA    . PRO B 2 259 ? 131.907 142.226 102.210 1.00 81.30  ? 259 PRO D CA    1 
ATOM   5254 C C     . PRO B 2 259 ? 130.738 141.744 103.048 1.00 81.30  ? 259 PRO D C     1 
ATOM   5255 O O     . PRO B 2 259 ? 130.834 140.698 103.688 1.00 81.30  ? 259 PRO D O     1 
ATOM   5256 C CB    . PRO B 2 259 ? 132.722 143.206 103.017 1.00 253.58 ? 259 PRO D CB    1 
ATOM   5257 C CG    . PRO B 2 259 ? 133.443 143.967 102.009 1.00 253.58 ? 259 PRO D CG    1 
ATOM   5258 C CD    . PRO B 2 259 ? 132.568 144.137 100.862 1.00 253.58 ? 259 PRO D CD    1 
ATOM   5259 N N     . ARG B 2 260 ? 129.657 142.486 103.116 1.00 83.71  ? 260 ARG D N     1 
ATOM   5260 C CA    . ARG B 2 260 ? 128.553 141.995 103.904 1.00 83.71  ? 260 ARG D CA    1 
ATOM   5261 C C     . ARG B 2 260 ? 127.891 140.823 103.223 1.00 83.71  ? 260 ARG D C     1 
ATOM   5262 O O     . ARG B 2 260 ? 127.405 139.908 103.890 1.00 83.71  ? 260 ARG D O     1 
ATOM   5263 C CB    . ARG B 2 260 ? 127.549 143.106 104.120 1.00 122.90 ? 260 ARG D CB    1 
ATOM   5264 C CG    . ARG B 2 260 ? 126.455 142.761 105.080 1.00 122.90 ? 260 ARG D CG    1 
ATOM   5265 C CD    . ARG B 2 260 ? 125.679 143.982 105.461 1.00 122.90 ? 260 ARG D CD    1 
ATOM   5266 N NE    . ARG B 2 260 ? 124.618 143.675 106.395 1.00 122.90 ? 260 ARG D NE    1 
ATOM   5267 C CZ    . ARG B 2 260 ? 124.786 143.582 107.700 1.00 122.90 ? 260 ARG D CZ    1 
ATOM   5268 N NH1   . ARG B 2 260 ? 125.965 143.765 108.253 1.00 122.90 ? 260 ARG D NH1   1 
ATOM   5269 N NH2   . ARG B 2 260 ? 123.747 143.294 108.471 1.00 122.90 ? 260 ARG D NH2   1 
ATOM   5270 N N     . ASN B 2 261 ? 127.869 140.815 101.903 1.00 84.79  ? 261 ASN D N     1 
ATOM   5271 C CA    . ASN B 2 261 ? 127.210 139.749 101.173 1.00 84.79  ? 261 ASN D CA    1 
ATOM   5272 C C     . ASN B 2 261 ? 128.160 138.601 100.885 1.00 84.79  ? 261 ASN D C     1 
ATOM   5273 O O     . ASN B 2 261 ? 128.545 138.356 99.744  1.00 84.79  ? 261 ASN D O     1 
ATOM   5274 C CB    . ASN B 2 261 ? 126.626 140.285 99.891  1.00 114.87 ? 261 ASN D CB    1 
ATOM   5275 C CG    . ASN B 2 261 ? 125.450 141.149 100.140 1.00 114.87 ? 261 ASN D CG    1 
ATOM   5276 O OD1   . ASN B 2 261 ? 124.737 140.978 101.129 1.00 114.87 ? 261 ASN D OD1   1 
ATOM   5277 N ND2   . ASN B 2 261 ? 125.216 142.087 99.253  1.00 114.87 ? 261 ASN D ND2   1 
ATOM   5278 N N     . HIS B 2 262 ? 128.509 137.877 101.933 1.00 84.32  ? 262 HIS D N     1 
ATOM   5279 C CA    . HIS B 2 262 ? 129.474 136.812 101.818 1.00 84.32  ? 262 HIS D CA    1 
ATOM   5280 C C     . HIS B 2 262 ? 128.877 135.448 101.869 1.00 84.32  ? 262 HIS D C     1 
ATOM   5281 O O     . HIS B 2 262 ? 129.609 134.472 102.035 1.00 84.32  ? 262 HIS D O     1 
ATOM   5282 C CB    . HIS B 2 262 ? 130.529 136.912 102.881 1.00 114.65 ? 262 HIS D CB    1 
ATOM   5283 C CG    . HIS B 2 262 ? 130.016 136.899 104.250 1.00 114.65 ? 262 HIS D CG    1 
ATOM   5284 N ND1   . HIS B 2 262 ? 129.765 138.047 104.945 1.00 114.65 ? 262 HIS D ND1   1 
ATOM   5285 C CD2   . HIS B 2 262 ? 129.766 135.883 105.087 1.00 114.65 ? 262 HIS D CD2   1 
ATOM   5286 C CE1   . HIS B 2 262 ? 129.346 137.736 106.150 1.00 114.65 ? 262 HIS D CE1   1 
ATOM   5287 N NE2   . HIS B 2 262 ? 129.335 136.427 106.262 1.00 114.65 ? 262 HIS D NE2   1 
ATOM   5288 N N     . PHE B 2 263 ? 127.590 135.324 101.753 1.00 83.72  ? 263 PHE D N     1 
ATOM   5289 C CA    . PHE B 2 263 ? 126.999 134.015 101.866 1.00 83.72  ? 263 PHE D CA    1 
ATOM   5290 C C     . PHE B 2 263 ? 126.945 133.365 100.510 1.00 83.72  ? 263 PHE D C     1 
ATOM   5291 O O     . PHE B 2 263 ? 126.390 133.929 99.568  1.00 83.72  ? 263 PHE D O     1 
ATOM   5292 C CB    . PHE B 2 263 ? 125.622 134.109 102.492 1.00 116.78 ? 263 PHE D CB    1 
ATOM   5293 C CG    . PHE B 2 263 ? 125.664 134.484 103.929 1.00 116.78 ? 263 PHE D CG    1 
ATOM   5294 C CD1   . PHE B 2 263 ? 125.853 133.538 104.874 1.00 116.78 ? 263 PHE D CD1   1 
ATOM   5295 C CD2   . PHE B 2 263 ? 125.543 135.771 104.329 1.00 116.78 ? 263 PHE D CD2   1 
ATOM   5296 C CE1   . PHE B 2 263 ? 125.907 133.859 106.167 1.00 116.78 ? 263 PHE D CE1   1 
ATOM   5297 C CE2   . PHE B 2 263 ? 125.602 136.089 105.628 1.00 116.78 ? 263 PHE D CE2   1 
ATOM   5298 C CZ    . PHE B 2 263 ? 125.782 135.141 106.544 1.00 116.78 ? 263 PHE D CZ    1 
ATOM   5299 N N     . LEU B 2 264 ? 127.497 132.176 100.413 1.00 84.63  ? 264 LEU D N     1 
ATOM   5300 C CA    . LEU B 2 264 ? 127.619 131.469 99.158  1.00 84.63  ? 264 LEU D CA    1 
ATOM   5301 C C     . LEU B 2 264 ? 126.758 130.216 99.069  1.00 84.63  ? 264 LEU D C     1 
ATOM   5302 O O     . LEU B 2 264 ? 126.398 129.598 100.063 1.00 84.63  ? 264 LEU D O     1 
ATOM   5303 C CB    . LEU B 2 264 ? 129.058 131.112 98.933  1.00 125.22 ? 264 LEU D CB    1 
ATOM   5304 C CG    . LEU B 2 264 ? 130.027 132.257 98.979  1.00 125.22 ? 264 LEU D CG    1 
ATOM   5305 C CD1   . LEU B 2 264 ? 131.365 131.685 98.883  1.00 125.22 ? 264 LEU D CD1   1 
ATOM   5306 C CD2   . LEU B 2 264 ? 129.813 133.186 97.890  1.00 125.22 ? 264 LEU D CD2   1 
ATOM   5307 N N     . MET B 2 265 ? 126.428 129.853 97.848  1.00 88.55  ? 265 MET D N     1 
ATOM   5308 C CA    . MET B 2 265 ? 125.628 128.700 97.500  1.00 88.55  ? 265 MET D CA    1 
ATOM   5309 C C     . MET B 2 265 ? 126.523 127.787 96.679  1.00 88.55  ? 265 MET D C     1 
ATOM   5310 O O     . MET B 2 265 ? 127.393 128.277 95.963  1.00 88.55  ? 265 MET D O     1 
ATOM   5311 C CB    . MET B 2 265 ? 124.435 129.179 96.695  1.00 127.17 ? 265 MET D CB    1 
ATOM   5312 C CG    . MET B 2 265 ? 123.737 130.326 97.335  1.00 127.17 ? 265 MET D CG    1 
ATOM   5313 S SD    . MET B 2 265 ? 122.824 129.844 98.746  1.00 127.17 ? 265 MET D SD    1 
ATOM   5314 C CE    . MET B 2 265 ? 121.304 129.495 97.952  1.00 127.17 ? 265 MET D CE    1 
ATOM   5315 N N     . THR B 2 266 ? 126.370 126.468 96.755  1.00 91.00  ? 266 THR D N     1 
ATOM   5316 C CA    . THR B 2 266 ? 127.276 125.611 95.990  1.00 91.00  ? 266 THR D CA    1 
ATOM   5317 C C     . THR B 2 266 ? 126.566 124.519 95.210  1.00 91.00  ? 266 THR D C     1 
ATOM   5318 O O     . THR B 2 266 ? 125.437 124.150 95.515  1.00 91.00  ? 266 THR D O     1 
ATOM   5319 C CB    . THR B 2 266 ? 128.287 124.955 96.882  1.00 127.38 ? 266 THR D CB    1 
ATOM   5320 O OG1   . THR B 2 266 ? 127.634 124.013 97.732  1.00 127.38 ? 266 THR D OG1   1 
ATOM   5321 C CG2   . THR B 2 266 ? 128.998 126.001 97.761  1.00 127.38 ? 266 THR D CG2   1 
ATOM   5322 N N     . SER B 2 267 ? 127.271 123.941 94.243  1.00 89.61  ? 267 SER D N     1 
ATOM   5323 C CA    . SER B 2 267 ? 126.725 122.833 93.481  1.00 89.61  ? 267 SER D CA    1 
ATOM   5324 C C     . SER B 2 267 ? 127.798 121.806 93.241  1.00 89.61  ? 267 SER D C     1 
ATOM   5325 O O     . SER B 2 267 ? 128.983 122.124 93.274  1.00 89.61  ? 267 SER D O     1 
ATOM   5326 C CB    . SER B 2 267 ? 126.143 123.261 92.142  1.00 120.70 ? 267 SER D CB    1 
ATOM   5327 O OG    . SER B 2 267 ? 127.130 123.680 91.247  1.00 120.70 ? 267 SER D OG    1 
ATOM   5328 N N     . MET B 2 268 ? 127.400 120.554 93.009  1.00 90.94  ? 268 MET D N     1 
ATOM   5329 C CA    . MET B 2 268 ? 128.386 119.499 92.838  1.00 90.94  ? 268 MET D CA    1 
ATOM   5330 C C     . MET B 2 268 ? 127.983 118.506 91.801  1.00 90.94  ? 268 MET D C     1 
ATOM   5331 O O     . MET B 2 268 ? 126.815 118.181 91.685  1.00 90.94  ? 268 MET D O     1 
ATOM   5332 C CB    . MET B 2 268 ? 128.568 118.657 94.049  1.00 130.60 ? 268 MET D CB    1 
ATOM   5333 C CG    . MET B 2 268 ? 128.870 119.376 95.276  1.00 130.60 ? 268 MET D CG    1 
ATOM   5334 S SD    . MET B 2 268 ? 129.173 118.227 96.596  1.00 130.60 ? 268 MET D SD    1 
ATOM   5335 C CE    . MET B 2 268 ? 130.805 117.643 96.170  1.00 130.60 ? 268 MET D CE    1 
ATOM   5336 N N     . SER B 2 269 ? 128.960 117.954 91.119  1.00 89.80  ? 269 SER D N     1 
ATOM   5337 C CA    . SER B 2 269 ? 128.698 116.822 90.286  1.00 89.80  ? 269 SER D CA    1 
ATOM   5338 C C     . SER B 2 269 ? 129.916 115.954 90.122  1.00 89.80  ? 269 SER D C     1 
ATOM   5339 O O     . SER B 2 269 ? 131.011 116.476 89.923  1.00 89.80  ? 269 SER D O     1 
ATOM   5340 C CB    . SER B 2 269 ? 128.209 117.191 88.912  1.00 120.95 ? 269 SER D CB    1 
ATOM   5341 O OG    . SER B 2 269 ? 128.029 116.005 88.161  1.00 120.95 ? 269 SER D OG    1 
ATOM   5342 N N     . PRO B 2 270 ? 129.777 114.685 90.236  1.00 86.48  ? 270 PRO D N     1 
ATOM   5343 C CA    . PRO B 2 270 ? 128.630 113.899 90.564  1.00 86.48  ? 270 PRO D CA    1 
ATOM   5344 C C     . PRO B 2 270 ? 128.258 113.884 92.015  1.00 86.48  ? 270 PRO D C     1 
ATOM   5345 O O     . PRO B 2 270 ? 129.112 114.030 92.869  1.00 86.48  ? 270 PRO D O     1 
ATOM   5346 C CB    . PRO B 2 270 ? 129.085 112.521 90.185  1.00 269.75 ? 270 PRO D CB    1 
ATOM   5347 C CG    . PRO B 2 270 ? 130.497 112.544 90.457  1.00 269.75 ? 270 PRO D CG    1 
ATOM   5348 C CD    . PRO B 2 270 ? 130.947 113.867 90.070  1.00 269.75 ? 270 PRO D CD    1 
ATOM   5349 N N     . LEU B 2 271 ? 126.985 113.638 92.305  1.00 92.65  ? 271 LEU D N     1 
ATOM   5350 C CA    . LEU B 2 271 ? 126.535 113.309 93.637  1.00 92.65  ? 271 LEU D CA    1 
ATOM   5351 C C     . LEU B 2 271 ? 126.467 111.805 93.686  1.00 92.65  ? 271 LEU D C     1 
ATOM   5352 O O     . LEU B 2 271 ? 126.122 111.170 92.694  1.00 92.65  ? 271 LEU D O     1 
ATOM   5353 C CB    . LEU B 2 271 ? 125.176 113.914 93.936  1.00 137.09 ? 271 LEU D CB    1 
ATOM   5354 C CG    . LEU B 2 271 ? 125.051 115.422 93.902  1.00 137.09 ? 271 LEU D CG    1 
ATOM   5355 C CD1   . LEU B 2 271 ? 123.614 115.828 94.033  1.00 137.09 ? 271 LEU D CD1   1 
ATOM   5356 C CD2   . LEU B 2 271 ? 125.850 116.047 95.015  1.00 137.09 ? 271 LEU D CD2   1 
ATOM   5357 N N     . GLU B 2 272 ? 126.813 111.211 94.815  1.00 93.19  ? 272 GLU D N     1 
ATOM   5358 C CA    . GLU B 2 272 ? 126.844 109.760 94.849  1.00 93.19  ? 272 GLU D CA    1 
ATOM   5359 C C     . GLU B 2 272 ? 125.980 109.204 95.965  1.00 93.19  ? 272 GLU D C     1 
ATOM   5360 O O     . GLU B 2 272 ? 126.478 108.775 97.001  1.00 93.19  ? 272 GLU D O     1 
ATOM   5361 C CB    . GLU B 2 272 ? 128.292 109.299 94.990  1.00 125.17 ? 272 GLU D CB    1 
ATOM   5362 C CG    . GLU B 2 272 ? 129.200 109.689 93.813  1.00 125.17 ? 272 GLU D CG    1 
ATOM   5363 C CD    . GLU B 2 272 ? 130.632 109.221 93.976  1.00 125.17 ? 272 GLU D CD    1 
ATOM   5364 O OE1   . GLU B 2 272 ? 131.240 109.540 94.998  1.00 125.17 ? 272 GLU D OE1   1 
ATOM   5365 O OE2   . GLU B 2 272 ? 131.144 108.534 93.086  1.00 125.17 ? 272 GLU D OE2   1 
ATOM   5366 N N     . THR B 2 273 ? 124.685 109.134 95.722  1.00 96.19  ? 273 THR D N     1 
ATOM   5367 C CA    . THR B 2 273 ? 123.801 108.596 96.732  1.00 96.19  ? 273 THR D CA    1 
ATOM   5368 C C     . THR B 2 273 ? 124.198 107.153 97.002  1.00 96.19  ? 273 THR D C     1 
ATOM   5369 O O     . THR B 2 273 ? 124.293 106.350 96.073  1.00 96.19  ? 273 THR D O     1 
ATOM   5370 C CB    . THR B 2 273 ? 122.353 108.642 96.255  1.00 134.65 ? 273 THR D CB    1 
ATOM   5371 O OG1   . THR B 2 273 ? 122.005 109.967 95.851  1.00 134.65 ? 273 THR D OG1   1 
ATOM   5372 C CG2   . THR B 2 273 ? 121.429 108.203 97.374  1.00 134.65 ? 273 THR D CG2   1 
ATOM   5373 N N     . SER B 2 274 ? 124.466 106.839 98.259  1.00 95.85  ? 274 SER D N     1 
ATOM   5374 C CA    . SER B 2 274 ? 124.822 105.501 98.733  1.00 95.85  ? 274 SER D CA    1 
ATOM   5375 C C     . SER B 2 274 ? 126.101 104.962 98.130  1.00 95.85  ? 274 SER D C     1 
ATOM   5376 O O     . SER B 2 274 ? 126.447 103.795 98.361  1.00 95.85  ? 274 SER D O     1 
ATOM   5377 C CB    . SER B 2 274 ? 123.715 104.497 98.458  1.00 129.10 ? 274 SER D CB    1 
ATOM   5378 O OG    . SER B 2 274 ? 122.506 104.874 99.061  1.00 129.10 ? 274 SER D OG    1 
ATOM   5379 N N     . LEU B 2 275 ? 126.790 105.777 97.346  1.00 93.79  ? 275 LEU D N     1 
ATOM   5380 C CA    . LEU B 2 275 ? 127.976 105.382 96.596  1.00 93.79  ? 275 LEU D CA    1 
ATOM   5381 C C     . LEU B 2 275 ? 127.678 104.271 95.577  1.00 93.79  ? 275 LEU D C     1 
ATOM   5382 O O     . LEU B 2 275 ? 128.575 103.505 95.218  1.00 93.79  ? 275 LEU D O     1 
ATOM   5383 C CB    . LEU B 2 275 ? 129.101 104.962 97.551  1.00 138.77 ? 275 LEU D CB    1 
ATOM   5384 C CG    . LEU B 2 275 ? 129.442 105.951 98.685  1.00 138.77 ? 275 LEU D CG    1 
ATOM   5385 C CD1   . LEU B 2 275 ? 130.562 105.376 99.533  1.00 138.77 ? 275 LEU D CD1   1 
ATOM   5386 C CD2   . LEU B 2 275 ? 129.819 107.338 98.139  1.00 138.77 ? 275 LEU D CD2   1 
ATOM   5387 N N     . THR B 2 276 ? 126.430 104.179 95.077  1.00 93.34  ? 276 THR D N     1 
ATOM   5388 C CA    . THR B 2 276 ? 126.032 103.155 94.100  1.00 93.34  ? 276 THR D CA    1 
ATOM   5389 C C     . THR B 2 276 ? 125.634 103.753 92.760  1.00 93.34  ? 276 THR D C     1 
ATOM   5390 O O     . THR B 2 276 ? 124.995 103.081 91.944  1.00 93.34  ? 276 THR D O     1 
ATOM   5391 C CB    . THR B 2 276 ? 124.851 102.316 94.601  1.00 130.66 ? 276 THR D CB    1 
ATOM   5392 O OG1   . THR B 2 276 ? 123.699 103.157 94.764  1.00 130.66 ? 276 THR D OG1   1 
ATOM   5393 C CG2   . THR B 2 276 ? 125.184 101.667 95.917  1.00 130.66 ? 276 THR D CG2   1 
ATOM   5394 N N     . SER B 2 277 ? 125.967 105.010 92.540  1.00 86.79  ? 277 SER D N     1 
ATOM   5395 C CA    . SER B 2 277 ? 125.540 105.776 91.379  1.00 86.79  ? 277 SER D CA    1 
ATOM   5396 C C     . SER B 2 277 ? 126.168 105.354 90.048  1.00 86.79  ? 277 SER D C     1 
ATOM   5397 O O     . SER B 2 277 ? 125.596 105.649 88.993  1.00 86.79  ? 277 SER D O     1 
ATOM   5398 C CB    . SER B 2 277 ? 125.868 107.227 91.645  1.00 116.90 ? 277 SER D CB    1 
ATOM   5399 O OG    . SER B 2 277 ? 127.260 107.367 91.822  1.00 116.90 ? 277 SER D OG    1 
ATOM   5400 N N     . ALA B 2 278 ? 127.325 104.704 90.056  1.00 83.07  ? 278 ALA D N     1 
ATOM   5401 C CA    . ALA B 2 278 ? 127.948 104.217 88.829  1.00 83.07  ? 278 ALA D CA    1 
ATOM   5402 C C     . ALA B 2 278 ? 128.152 105.297 87.774  1.00 83.07  ? 278 ALA D C     1 
ATOM   5403 O O     . ALA B 2 278 ? 127.861 105.091 86.600  1.00 83.07  ? 278 ALA D O     1 
ATOM   5404 C CB    . ALA B 2 278 ? 127.128 103.084 88.235  1.00 113.28 ? 278 ALA D CB    1 
ATOM   5405 N N     . HIS B 2 279 ? 128.700 106.438 88.164  1.00 85.94  ? 279 HIS D N     1 
ATOM   5406 C CA    . HIS B 2 279 ? 128.951 107.478 87.176  1.00 85.94  ? 279 HIS D CA    1 
ATOM   5407 C C     . HIS B 2 279 ? 130.178 107.119 86.382  1.00 85.94  ? 279 HIS D C     1 
ATOM   5408 O O     . HIS B 2 279 ? 131.243 107.709 86.547  1.00 85.94  ? 279 HIS D O     1 
ATOM   5409 C CB    . HIS B 2 279 ? 129.208 108.815 87.803  1.00 116.86 ? 279 HIS D CB    1 
ATOM   5410 C CG    . HIS B 2 279 ? 128.061 109.357 88.543  1.00 116.86 ? 279 HIS D CG    1 
ATOM   5411 N ND1   . HIS B 2 279 ? 126.908 109.799 87.934  1.00 116.86 ? 279 HIS D ND1   1 
ATOM   5412 C CD2   . HIS B 2 279 ? 127.898 109.554 89.862  1.00 116.86 ? 279 HIS D CD2   1 
ATOM   5413 C CE1   . HIS B 2 279 ? 126.080 110.249 88.858  1.00 116.86 ? 279 HIS D CE1   1 
ATOM   5414 N NE2   . HIS B 2 279 ? 126.662 110.118 90.035  1.00 116.86 ? 279 HIS D NE2   1 
ATOM   5415 N N     . GLN B 2 280 ? 129.996 106.143 85.510  1.00 91.45  ? 280 GLN D N     1 
ATOM   5416 C CA    . GLN B 2 280 ? 131.117 105.566 84.789  1.00 91.45  ? 280 GLN D CA    1 
ATOM   5417 C C     . GLN B 2 280 ? 131.773 106.578 83.874  1.00 91.45  ? 280 GLN D C     1 
ATOM   5418 O O     . GLN B 2 280 ? 132.996 106.566 83.693  1.00 91.45  ? 280 GLN D O     1 
ATOM   5419 C CB    . GLN B 2 280 ? 130.645 104.362 83.986  1.00 127.75 ? 280 GLN D CB    1 
ATOM   5420 C CG    . GLN B 2 280 ? 130.258 103.166 84.836  1.00 127.75 ? 280 GLN D CG    1 
ATOM   5421 C CD    . GLN B 2 280 ? 129.741 102.013 84.002  1.00 127.75 ? 280 GLN D CD    1 
ATOM   5422 O OE1   . GLN B 2 280 ? 129.316 102.204 82.861  1.00 127.75 ? 280 GLN D OE1   1 
ATOM   5423 N NE2   . GLN B 2 280 ? 129.778 100.810 84.562  1.00 127.75 ? 280 GLN D NE2   1 
ATOM   5424 N N     . LYS B 2 281 ? 130.979 107.444 83.267  1.00 91.55  ? 281 LYS D N     1 
ATOM   5425 C CA    . LYS B 2 281 ? 131.568 108.425 82.385  1.00 91.55  ? 281 LYS D CA    1 
ATOM   5426 C C     . LYS B 2 281 ? 130.774 109.710 82.387  1.00 91.55  ? 281 LYS D C     1 
ATOM   5427 O O     . LYS B 2 281 ? 129.559 109.714 82.199  1.00 91.55  ? 281 LYS D O     1 
ATOM   5428 C CB    . LYS B 2 281 ? 131.676 107.893 80.962  1.00 137.20 ? 281 LYS D CB    1 
ATOM   5429 C CG    . LYS B 2 281 ? 132.398 108.850 80.010  1.00 137.20 ? 281 LYS D CG    1 
ATOM   5430 C CD    . LYS B 2 281 ? 132.585 108.237 78.633  1.00 137.20 ? 281 LYS D CD    1 
ATOM   5431 C CE    . LYS B 2 281 ? 133.358 109.176 77.716  1.00 137.20 ? 281 LYS D CE    1 
ATOM   5432 N NZ    . LYS B 2 281 ? 133.488 108.628 76.340  1.00 137.20 ? 281 LYS D NZ    1 
ATOM   5433 N N     . ILE B 2 282 ? 131.490 110.784 82.578  1.00 89.48  ? 282 ILE D N     1 
ATOM   5434 C CA    . ILE B 2 282 ? 130.986 112.121 82.486  1.00 89.48  ? 282 ILE D CA    1 
ATOM   5435 C C     . ILE B 2 282 ? 131.850 112.776 81.452  1.00 89.48  ? 282 ILE D C     1 
ATOM   5436 O O     . ILE B 2 282 ? 133.074 112.673 81.530  1.00 89.48  ? 282 ILE D O     1 
ATOM   5437 C CB    . ILE B 2 282 ? 131.111 112.844 83.826  1.00 132.40 ? 282 ILE D CB    1 
ATOM   5438 C CG1   . ILE B 2 282 ? 130.337 112.092 84.908  1.00 132.40 ? 282 ILE D CG1   1 
ATOM   5439 C CG2   . ILE B 2 282 ? 130.634 114.250 83.695  1.00 132.40 ? 282 ILE D CG2   1 
ATOM   5440 C CD1   . ILE B 2 282 ? 130.606 112.572 86.355  1.00 132.40 ? 282 ILE D CD1   1 
ATOM   5441 N N     . GLU B 2 283 ? 131.256 113.387 80.467  1.00 92.49  ? 283 GLU D N     1 
ATOM   5442 C CA    . GLU B 2 283 ? 132.042 114.128 79.495  1.00 92.49  ? 283 GLU D CA    1 
ATOM   5443 C C     . GLU B 2 283 ? 132.238 115.540 80.017  1.00 92.49  ? 283 GLU D C     1 
ATOM   5444 O O     . GLU B 2 283 ? 131.458 116.009 80.842  1.00 92.49  ? 283 GLU D O     1 
ATOM   5445 C CB    . GLU B 2 283 ? 131.322 114.148 78.162  1.00 124.23 ? 283 GLU D CB    1 
ATOM   5446 C CG    . GLU B 2 283 ? 131.125 112.798 77.537  1.00 124.23 ? 283 GLU D CG    1 
ATOM   5447 C CD    . GLU B 2 283 ? 130.484 112.908 76.178  1.00 124.23 ? 283 GLU D CD    1 
ATOM   5448 O OE1   . GLU B 2 283 ? 130.206 114.034 75.767  1.00 124.23 ? 283 GLU D OE1   1 
ATOM   5449 O OE2   . GLU B 2 283 ? 130.257 111.887 75.520  1.00 124.23 ? 283 GLU D OE2   1 
ATOM   5450 N N     . THR B 2 284 ? 133.257 116.243 79.521  1.00 93.47  ? 284 THR D N     1 
ATOM   5451 C CA    . THR B 2 284 ? 133.499 117.599 80.012  1.00 93.47  ? 284 THR D CA    1 
ATOM   5452 C C     . THR B 2 284 ? 132.291 118.501 79.805  1.00 93.47  ? 284 THR D C     1 
ATOM   5453 O O     . THR B 2 284 ? 131.918 119.280 80.701  1.00 93.47  ? 284 THR D O     1 
ATOM   5454 C CB    . THR B 2 284 ? 134.721 118.190 79.336  1.00 130.84 ? 284 THR D CB    1 
ATOM   5455 O OG1   . THR B 2 284 ? 135.844 117.352 79.609  1.00 130.84 ? 284 THR D OG1   1 
ATOM   5456 C CG2   . THR B 2 284 ? 135.027 119.575 79.884  1.00 130.84 ? 284 THR D CG2   1 
ATOM   5457 N N     . LYS B 2 285 ? 131.653 118.412 78.651  1.00 89.40  ? 285 LYS D N     1 
ATOM   5458 C CA    . LYS B 2 285 ? 130.518 119.277 78.400  1.00 89.40  ? 285 LYS D CA    1 
ATOM   5459 C C     . LYS B 2 285 ? 129.399 119.010 79.376  1.00 89.40  ? 285 LYS D C     1 
ATOM   5460 O O     . LYS B 2 285 ? 128.698 119.940 79.817  1.00 89.40  ? 285 LYS D O     1 
ATOM   5461 C CB    . LYS B 2 285 ? 129.999 119.088 76.999  1.00 133.98 ? 285 LYS D CB    1 
ATOM   5462 C CG    . LYS B 2 285 ? 130.860 119.634 75.978  1.00 133.98 ? 285 LYS D CG    1 
ATOM   5463 C CD    . LYS B 2 285 ? 130.269 119.431 74.611  1.00 133.98 ? 285 LYS D CD    1 
ATOM   5464 C CE    . LYS B 2 285 ? 131.180 119.999 73.530  1.00 133.98 ? 285 LYS D CE    1 
ATOM   5465 N NZ    . LYS B 2 285 ? 130.638 119.764 72.160  1.00 133.98 ? 285 LYS D NZ    1 
ATOM   5466 N N     . GLU B 2 286 ? 129.183 117.750 79.702  1.00 91.95  ? 286 GLU D N     1 
ATOM   5467 C CA    . GLU B 2 286 ? 128.114 117.430 80.623  1.00 91.95  ? 286 GLU D CA    1 
ATOM   5468 C C     . GLU B 2 286 ? 128.460 117.893 82.012  1.00 91.95  ? 286 GLU D C     1 
ATOM   5469 O O     . GLU B 2 286 ? 127.591 118.357 82.735  1.00 91.95  ? 286 GLU D O     1 
ATOM   5470 C CB    . GLU B 2 286 ? 127.818 115.956 80.629  1.00 123.50 ? 286 GLU D CB    1 
ATOM   5471 C CG    . GLU B 2 286 ? 127.204 115.450 79.375  1.00 123.50 ? 286 GLU D CG    1 
ATOM   5472 C CD    . GLU B 2 286 ? 126.961 113.994 79.482  1.00 123.50 ? 286 GLU D CD    1 
ATOM   5473 O OE1   . GLU B 2 286 ? 127.468 113.414 80.442  1.00 123.50 ? 286 GLU D OE1   1 
ATOM   5474 O OE2   . GLU B 2 286 ? 126.260 113.428 78.647  1.00 123.50 ? 286 GLU D OE2   1 
ATOM   5475 N N     . LEU B 2 287 ? 129.709 117.792 82.412  1.00 91.74  ? 287 LEU D N     1 
ATOM   5476 C CA    . LEU B 2 287 ? 130.008 118.189 83.762  1.00 91.74  ? 287 LEU D CA    1 
ATOM   5477 C C     . LEU B 2 287 ? 129.608 119.621 83.964  1.00 91.74  ? 287 LEU D C     1 
ATOM   5478 O O     . LEU B 2 287 ? 128.997 119.960 84.984  1.00 91.74  ? 287 LEU D O     1 
ATOM   5479 C CB    . LEU B 2 287 ? 131.475 117.973 84.062  1.00 135.74 ? 287 LEU D CB    1 
ATOM   5480 C CG    . LEU B 2 287 ? 132.000 118.356 85.425  1.00 135.74 ? 287 LEU D CG    1 
ATOM   5481 C CD1   . LEU B 2 287 ? 131.303 117.589 86.492  1.00 135.74 ? 287 LEU D CD1   1 
ATOM   5482 C CD2   . LEU B 2 287 ? 133.488 118.080 85.466  1.00 135.74 ? 287 LEU D CD2   1 
ATOM   5483 N N     . MET B 2 288 ? 129.887 120.480 82.994  1.00 93.32  ? 288 MET D N     1 
ATOM   5484 C CA    . MET B 2 288 ? 129.460 121.850 83.229  1.00 93.32  ? 288 MET D CA    1 
ATOM   5485 C C     . MET B 2 288 ? 127.949 121.994 83.214  1.00 93.32  ? 288 MET D C     1 
ATOM   5486 O O     . MET B 2 288 ? 127.397 122.775 84.010  1.00 93.32  ? 288 MET D O     1 
ATOM   5487 C CB    . MET B 2 288 ? 130.108 122.792 82.262  1.00 134.02 ? 288 MET D CB    1 
ATOM   5488 C CG    . MET B 2 288 ? 131.515 123.030 82.607  1.00 134.02 ? 288 MET D CG    1 
ATOM   5489 S SD    . MET B 2 288 ? 132.284 124.053 81.424  1.00 134.02 ? 288 MET D SD    1 
ATOM   5490 C CE    . MET B 2 288 ? 131.591 125.666 81.729  1.00 134.02 ? 288 MET D CE    1 
ATOM   5491 N N     . GLN B 2 289 ? 127.247 121.252 82.360  1.00 90.49  ? 289 GLN D N     1 
ATOM   5492 C CA    . GLN B 2 289 ? 125.799 121.398 82.423  1.00 90.49  ? 289 GLN D CA    1 
ATOM   5493 C C     . GLN B 2 289 ? 125.249 120.896 83.749  1.00 90.49  ? 289 GLN D C     1 
ATOM   5494 O O     . GLN B 2 289 ? 124.290 121.461 84.271  1.00 90.49  ? 289 GLN D O     1 
ATOM   5495 C CB    . GLN B 2 289 ? 125.104 120.687 81.282  1.00 126.41 ? 289 GLN D CB    1 
ATOM   5496 C CG    . GLN B 2 289 ? 125.377 121.277 79.955  1.00 126.41 ? 289 GLN D CG    1 
ATOM   5497 C CD    . GLN B 2 289 ? 124.952 122.692 79.859  1.00 126.41 ? 289 GLN D CD    1 
ATOM   5498 O OE1   . GLN B 2 289 ? 123.872 123.073 80.314  1.00 126.41 ? 289 GLN D OE1   1 
ATOM   5499 N NE2   . GLN B 2 289 ? 125.798 123.510 79.253  1.00 126.41 ? 289 GLN D NE2   1 
ATOM   5500 N N     . ASP B 2 290 ? 125.837 119.856 84.323  1.00 93.11  ? 290 ASP D N     1 
ATOM   5501 C CA    . ASP B 2 290 ? 125.342 119.378 85.602  1.00 93.11  ? 290 ASP D CA    1 
ATOM   5502 C C     . ASP B 2 290 ? 125.540 120.430 86.655  1.00 93.11  ? 290 ASP D C     1 
ATOM   5503 O O     . ASP B 2 290 ? 124.675 120.636 87.505  1.00 93.11  ? 290 ASP D O     1 
ATOM   5504 C CB    . ASP B 2 290 ? 126.093 118.150 86.107  1.00 119.71 ? 290 ASP D CB    1 
ATOM   5505 C CG    . ASP B 2 290 ? 125.787 116.856 85.413  1.00 119.71 ? 290 ASP D CG    1 
ATOM   5506 O OD1   . ASP B 2 290 ? 124.843 116.725 84.636  1.00 119.71 ? 290 ASP D OD1   1 
ATOM   5507 O OD2   . ASP B 2 290 ? 126.538 115.922 85.717  1.00 119.71 ? 290 ASP D OD2   1 
ATOM   5508 N N     . LEU B 2 291 ? 126.683 121.076 86.636  1.00 89.85  ? 291 LEU D N     1 
ATOM   5509 C CA    . LEU B 2 291 ? 126.973 122.016 87.687  1.00 89.85  ? 291 LEU D CA    1 
ATOM   5510 C C     . LEU B 2 291 ? 126.036 123.207 87.666  1.00 89.85  ? 291 LEU D C     1 
ATOM   5511 O O     . LEU B 2 291 ? 125.788 123.802 88.724  1.00 89.85  ? 291 LEU D O     1 
ATOM   5512 C CB    . LEU B 2 291 ? 128.416 122.431 87.584  1.00 132.94 ? 291 LEU D CB    1 
ATOM   5513 C CG    . LEU B 2 291 ? 129.404 121.354 87.959  1.00 132.94 ? 291 LEU D CG    1 
ATOM   5514 C CD1   . LEU B 2 291 ? 130.793 121.815 87.658  1.00 132.94 ? 291 LEU D CD1   1 
ATOM   5515 C CD2   . LEU B 2 291 ? 129.301 120.982 89.418  1.00 132.94 ? 291 LEU D CD2   1 
ATOM   5516 N N     . ILE B 2 292 ? 125.542 123.594 86.484  1.00 89.46  ? 292 ILE D N     1 
ATOM   5517 C CA    . ILE B 2 292 ? 124.591 124.699 86.393  1.00 89.46  ? 292 ILE D CA    1 
ATOM   5518 C C     . ILE B 2 292 ? 123.172 124.253 86.675  1.00 89.46  ? 292 ILE D C     1 
ATOM   5519 O O     . ILE B 2 292 ? 122.379 125.010 87.222  1.00 89.46  ? 292 ILE D O     1 
ATOM   5520 C CB    . ILE B 2 292 ? 124.689 125.406 85.048  1.00 132.37 ? 292 ILE D CB    1 
ATOM   5521 C CG1   . ILE B 2 292 ? 123.821 126.610 85.110  1.00 132.37 ? 292 ILE D CG1   1 
ATOM   5522 C CG2   . ILE B 2 292 ? 124.259 124.554 83.936  1.00 132.37 ? 292 ILE D CG2   1 
ATOM   5523 C CD1   . ILE B 2 292 ? 124.012 127.619 84.023  1.00 132.37 ? 292 ILE D CD1   1 
ATOM   5524 N N     . ASP B 2 293 ? 122.836 123.022 86.338  1.00 92.96  ? 293 ASP D N     1 
ATOM   5525 C CA    . ASP B 2 293 ? 121.485 122.486 86.471  1.00 92.96  ? 293 ASP D CA    1 
ATOM   5526 C C     . ASP B 2 293 ? 120.967 122.409 87.896  1.00 92.96  ? 293 ASP D C     1 
ATOM   5527 O O     . ASP B 2 293 ? 121.688 122.096 88.847  1.00 92.96  ? 293 ASP D O     1 
ATOM   5528 C CB    . ASP B 2 293 ? 121.412 121.090 85.869  1.00 119.52 ? 293 ASP D CB    1 
ATOM   5529 C CG    . ASP B 2 293 ? 120.011 120.568 85.807  1.00 119.52 ? 293 ASP D CG    1 
ATOM   5530 O OD1   . ASP B 2 293 ? 119.501 120.068 86.814  1.00 119.52 ? 293 ASP D OD1   1 
ATOM   5531 O OD2   . ASP B 2 293 ? 119.385 120.709 84.757  1.00 119.52 ? 293 ASP D OD2   1 
ATOM   5532 N N     . GLN B 2 294 ? 119.665 122.619 88.000  1.00 90.87  ? 294 GLN D N     1 
ATOM   5533 C CA    . GLN B 2 294 ? 118.916 122.690 89.242  1.00 90.87  ? 294 GLN D CA    1 
ATOM   5534 C C     . GLN B 2 294 ? 119.105 121.506 90.167  1.00 90.87  ? 294 GLN D C     1 
ATOM   5535 O O     . GLN B 2 294 ? 119.165 121.677 91.384  1.00 90.87  ? 294 GLN D O     1 
ATOM   5536 C CB    . GLN B 2 294 ? 117.458 122.802 88.878  1.00 126.94 ? 294 GLN D CB    1 
ATOM   5537 C CG    . GLN B 2 294 ? 116.512 122.980 89.994  1.00 126.94 ? 294 GLN D CG    1 
ATOM   5538 C CD    . GLN B 2 294 ? 115.108 123.057 89.458  1.00 126.94 ? 294 GLN D CD    1 
ATOM   5539 O OE1   . GLN B 2 294 ? 114.694 122.185 88.700  1.00 126.94 ? 294 GLN D OE1   1 
ATOM   5540 N NE2   . GLN B 2 294 ? 114.377 124.110 89.806  1.00 126.94 ? 294 GLN D NE2   1 
ATOM   5541 N N     . ASP B 2 295 ? 119.209 120.302 89.639  1.00 88.65  ? 295 ASP D N     1 
ATOM   5542 C CA    . ASP B 2 295 ? 119.228 119.155 90.538  1.00 88.65  ? 295 ASP D CA    1 
ATOM   5543 C C     . ASP B 2 295 ? 120.594 118.808 91.085  1.00 88.65  ? 295 ASP D C     1 
ATOM   5544 O O     . ASP B 2 295 ? 120.749 117.790 91.749  1.00 88.65  ? 295 ASP D O     1 
ATOM   5545 C CB    . ASP B 2 295 ? 118.617 117.954 89.858  1.00 113.98 ? 295 ASP D CB    1 
ATOM   5546 C CG    . ASP B 2 295 ? 117.116 118.059 89.775  1.00 113.98 ? 295 ASP D CG    1 
ATOM   5547 O OD1   . ASP B 2 295 ? 116.494 118.755 90.601  1.00 113.98 ? 295 ASP D OD1   1 
ATOM   5548 O OD2   . ASP B 2 295 ? 116.541 117.428 88.891  1.00 113.98 ? 295 ASP D OD2   1 
ATOM   5549 N N     . HIS B 2 296 ? 121.583 119.634 90.853  1.00 89.34  ? 296 HIS D N     1 
ATOM   5550 C CA    . HIS B 2 296 ? 122.863 119.443 91.455  1.00 89.34  ? 296 HIS D CA    1 
ATOM   5551 C C     . HIS B 2 296 ? 123.200 120.592 92.363  1.00 89.34  ? 296 HIS D C     1 
ATOM   5552 O O     . HIS B 2 296 ? 124.323 120.666 92.860  1.00 89.34  ? 296 HIS D O     1 
ATOM   5553 C CB    . HIS B 2 296 ? 123.891 119.303 90.385  1.00 121.48 ? 296 HIS D CB    1 
ATOM   5554 C CG    . HIS B 2 296 ? 123.667 118.136 89.531  1.00 121.48 ? 296 HIS D CG    1 
ATOM   5555 N ND1   . HIS B 2 296 ? 123.997 116.873 89.925  1.00 121.48 ? 296 HIS D ND1   1 
ATOM   5556 C CD2   . HIS B 2 296 ? 123.176 118.027 88.290  1.00 121.48 ? 296 HIS D CD2   1 
ATOM   5557 C CE1   . HIS B 2 296 ? 123.707 116.028 88.965  1.00 121.48 ? 296 HIS D CE1   1 
ATOM   5558 N NE2   . HIS B 2 296 ? 123.208 116.705 87.960  1.00 121.48 ? 296 HIS D NE2   1 
ATOM   5559 N N     . ILE B 2 297 ? 122.264 121.498 92.608  1.00 86.67  ? 297 ILE D N     1 
ATOM   5560 C CA    . ILE B 2 297 ? 122.531 122.634 93.477  1.00 86.67  ? 297 ILE D CA    1 
ATOM   5561 C C     . ILE B 2 297 ? 122.063 122.272 94.854  1.00 86.67  ? 297 ILE D C     1 
ATOM   5562 O O     . ILE B 2 297 ? 120.891 121.963 95.055  1.00 86.67  ? 297 ILE D O     1 
ATOM   5563 C CB    . ILE B 2 297 ? 121.856 123.914 93.003  1.00 128.24 ? 297 ILE D CB    1 
ATOM   5564 C CG1   . ILE B 2 297 ? 122.336 124.282 91.628  1.00 128.24 ? 297 ILE D CG1   1 
ATOM   5565 C CG2   . ILE B 2 297 ? 122.176 125.026 93.970  1.00 128.24 ? 297 ILE D CG2   1 
ATOM   5566 C CD1   . ILE B 2 297 ? 121.562 125.399 90.947  1.00 128.24 ? 297 ILE D CD1   1 
ATOM   5567 N N     . LEU B 2 298 ? 122.938 122.338 95.816  1.00 87.71  ? 298 LEU D N     1 
ATOM   5568 C CA    . LEU B 2 298 ? 122.568 121.919 97.137  1.00 87.71  ? 298 LEU D CA    1 
ATOM   5569 C C     . LEU B 2 298 ? 122.065 123.109 97.949  1.00 87.71  ? 298 LEU D C     1 
ATOM   5570 O O     . LEU B 2 298 ? 122.563 123.451 99.015  1.00 87.71  ? 298 LEU D O     1 
ATOM   5571 C CB    . LEU B 2 298 ? 123.749 121.215 97.759  1.00 129.78 ? 298 LEU D CB    1 
ATOM   5572 C CG    . LEU B 2 298 ? 124.311 120.071 96.903  1.00 129.78 ? 298 LEU D CG    1 
ATOM   5573 C CD1   . LEU B 2 298 ? 125.478 119.422 97.590  1.00 129.78 ? 298 LEU D CD1   1 
ATOM   5574 C CD2   . LEU B 2 298 ? 123.257 119.029 96.584  1.00 129.78 ? 298 LEU D CD2   1 
ATOM   5575 N N     . ALA B 2 299 ? 121.022 123.716 97.411  1.00 88.24  ? 299 ALA D N     1 
ATOM   5576 C CA    . ALA B 2 299 ? 120.322 124.853 97.962  1.00 88.24  ? 299 ALA D CA    1 
ATOM   5577 C C     . ALA B 2 299 ? 119.007 125.008 97.215  1.00 88.24  ? 299 ALA D C     1 
ATOM   5578 O O     . ALA B 2 299 ? 118.927 124.615 96.055  1.00 88.24  ? 299 ALA D O     1 
ATOM   5579 C CB    . ALA B 2 299 ? 121.187 126.086 97.827  1.00 120.33 ? 299 ALA D CB    1 
ATOM   5580 N N     . PRO B 2 300 ? 117.994 125.604 97.784  1.00 85.99  ? 300 PRO D N     1 
ATOM   5581 C CA    . PRO B 2 300 ? 116.689 125.787 97.147  1.00 85.99  ? 300 PRO D CA    1 
ATOM   5582 C C     . PRO B 2 300 ? 116.640 126.954 96.189  1.00 85.99  ? 300 PRO D C     1 
ATOM   5583 O O     . PRO B 2 300 ? 115.852 127.863 96.349  1.00 85.99  ? 300 PRO D O     1 
ATOM   5584 C CB    . PRO B 2 300 ? 115.786 126.045 98.342  1.00 268.21 ? 300 PRO D CB    1 
ATOM   5585 C CG    . PRO B 2 300 ? 116.681 126.759 99.295  1.00 268.21 ? 300 PRO D CG    1 
ATOM   5586 C CD    . PRO B 2 300 ? 118.014 126.100 99.155  1.00 268.21 ? 300 PRO D CD    1 
ATOM   5587 N N     . ILE B 2 301 ? 117.500 126.941 95.198  1.00 84.92  ? 301 ILE D N     1 
ATOM   5588 C CA    . ILE B 2 301 ? 117.523 128.015 94.231  1.00 84.92  ? 301 ILE D CA    1 
ATOM   5589 C C     . ILE B 2 301 ? 117.546 127.435 92.840  1.00 84.92  ? 301 ILE D C     1 
ATOM   5590 O O     . ILE B 2 301 ? 117.927 126.289 92.628  1.00 84.92  ? 301 ILE D O     1 
ATOM   5591 C CB    . ILE B 2 301 ? 118.706 128.957 94.415  1.00 125.65 ? 301 ILE D CB    1 
ATOM   5592 C CG1   . ILE B 2 301 ? 120.033 128.256 94.221  1.00 125.65 ? 301 ILE D CG1   1 
ATOM   5593 C CG2   . ILE B 2 301 ? 118.626 129.548 95.763  1.00 125.65 ? 301 ILE D CG2   1 
ATOM   5594 C CD1   . ILE B 2 301 ? 121.225 129.160 94.156  1.00 125.65 ? 301 ILE D CD1   1 
ATOM   5595 N N     . THR B 2 302 ? 117.151 128.239 91.878  1.00 85.24  ? 302 THR D N     1 
ATOM   5596 C CA    . THR B 2 302 ? 117.257 127.834 90.497  1.00 85.24  ? 302 THR D CA    1 
ATOM   5597 C C     . THR B 2 302 ? 118.142 128.859 89.832  1.00 85.24  ? 302 THR D C     1 
ATOM   5598 O O     . THR B 2 302 ? 117.948 130.055 90.033  1.00 85.24  ? 302 THR D O     1 
ATOM   5599 C CB    . THR B 2 302 ? 115.894 127.749 89.845  1.00 119.32 ? 302 THR D CB    1 
ATOM   5600 O OG1   . THR B 2 302 ? 115.087 126.830 90.581  1.00 119.32 ? 302 THR D OG1   1 
ATOM   5601 C CG2   . THR B 2 302 ? 116.018 127.249 88.441  1.00 119.32 ? 302 THR D CG2   1 
ATOM   5602 N N     . VAL B 2 303 ? 119.129 128.408 89.072  1.00 89.26  ? 303 VAL D N     1 
ATOM   5603 C CA    . VAL B 2 303 ? 120.107 129.298 88.469  1.00 89.26  ? 303 VAL D CA    1 
ATOM   5604 C C     . VAL B 2 303 ? 119.504 130.233 87.455  1.00 89.26  ? 303 VAL D C     1 
ATOM   5605 O O     . VAL B 2 303 ? 120.098 131.239 87.098  1.00 89.26  ? 303 VAL D O     1 
ATOM   5606 C CB    . VAL B 2 303 ? 121.180 128.475 87.803  1.00 129.79 ? 303 VAL D CB    1 
ATOM   5607 C CG1   . VAL B 2 303 ? 120.619 127.866 86.508  1.00 129.79 ? 303 VAL D CG1   1 
ATOM   5608 C CG2   . VAL B 2 303 ? 122.390 129.325 87.547  1.00 129.79 ? 303 VAL D CG2   1 
ATOM   5609 N N     . GLU B 2 304 ? 118.336 129.909 86.974  1.00 89.57  ? 304 GLU D N     1 
ATOM   5610 C CA    . GLU B 2 304 ? 117.627 130.683 85.993  1.00 89.57  ? 304 GLU D CA    1 
ATOM   5611 C C     . GLU B 2 304 ? 117.022 131.927 86.589  1.00 89.57  ? 304 GLU D C     1 
ATOM   5612 O O     . GLU B 2 304 ? 116.522 132.775 85.845  1.00 89.57  ? 304 GLU D O     1 
ATOM   5613 C CB    . GLU B 2 304 ? 116.518 129.828 85.408  1.00 120.31 ? 304 GLU D CB    1 
ATOM   5614 C CG    . GLU B 2 304 ? 117.001 128.586 84.687  1.00 120.31 ? 304 GLU D CG    1 
ATOM   5615 C CD    . GLU B 2 304 ? 115.869 127.733 84.176  1.00 120.31 ? 304 GLU D CD    1 
ATOM   5616 O OE1   . GLU B 2 304 ? 114.714 128.128 84.337  1.00 120.31 ? 304 GLU D OE1   1 
ATOM   5617 O OE2   . GLU B 2 304 ? 116.134 126.662 83.627  1.00 120.31 ? 304 GLU D OE2   1 
ATOM   5618 N N     . LYS B 2 305 ? 117.000 132.034 87.908  1.00 86.78  ? 305 LYS D N     1 
ATOM   5619 C CA    . LYS B 2 305 ? 116.410 133.165 88.604  1.00 86.78  ? 305 LYS D CA    1 
ATOM   5620 C C     . LYS B 2 305 ? 117.481 133.916 89.360  1.00 86.78  ? 305 LYS D C     1 
ATOM   5621 O O     . LYS B 2 305 ? 118.466 133.338 89.796  1.00 86.78  ? 305 LYS D O     1 
ATOM   5622 C CB    . LYS B 2 305 ? 115.348 132.704 89.584  1.00 130.05 ? 305 LYS D CB    1 
ATOM   5623 C CG    . LYS B 2 305 ? 114.224 131.881 88.958  1.00 130.05 ? 305 LYS D CG    1 
ATOM   5624 C CD    . LYS B 2 305 ? 113.373 132.691 87.980  1.00 130.05 ? 305 LYS D CD    1 
ATOM   5625 C CE    . LYS B 2 305 ? 112.185 131.881 87.469  1.00 130.05 ? 305 LYS D CE    1 
ATOM   5626 N NZ    . LYS B 2 305 ? 111.362 132.643 86.482  1.00 130.05 ? 305 LYS D NZ    1 
ATOM   5627 N N     . GLY B 2 306 ? 117.287 135.194 89.503  1.00 88.12  ? 306 GLY D N     1 
ATOM   5628 C CA    . GLY B 2 306 ? 118.178 135.996 90.309  1.00 88.12  ? 306 GLY D CA    1 
ATOM   5629 C C     . GLY B 2 306 ? 119.424 136.392 89.559  1.00 88.12  ? 306 GLY D C     1 
ATOM   5630 O O     . GLY B 2 306 ? 119.495 136.274 88.346  1.00 88.12  ? 306 GLY D O     1 
ATOM   5631 N N     . VAL B 2 307 ? 120.397 136.904 90.290  1.00 89.65  ? 307 VAL D N     1 
ATOM   5632 C CA    . VAL B 2 307 ? 121.615 137.387 89.685  1.00 89.65  ? 307 VAL D CA    1 
ATOM   5633 C C     . VAL B 2 307 ? 122.822 136.894 90.426  1.00 89.65  ? 307 VAL D C     1 
ATOM   5634 O O     . VAL B 2 307 ? 122.776 136.600 91.620  1.00 89.65  ? 307 VAL D O     1 
ATOM   5635 C CB    . VAL B 2 307 ? 121.695 138.890 89.643  1.00 130.36 ? 307 VAL D CB    1 
ATOM   5636 C CG1   . VAL B 2 307 ? 120.597 139.431 88.784  1.00 130.36 ? 307 VAL D CG1   1 
ATOM   5637 C CG2   . VAL B 2 307 ? 121.603 139.456 91.056  1.00 130.36 ? 307 VAL D CG2   1 
ATOM   5638 N N     . PHE B 2 308 ? 123.926 136.893 89.716  1.00 89.90  ? 308 PHE D N     1 
ATOM   5639 C CA    . PHE B 2 308 ? 125.192 136.532 90.291  1.00 89.90  ? 308 PHE D CA    1 
ATOM   5640 C C     . PHE B 2 308 ? 126.030 137.747 90.589  1.00 89.90  ? 308 PHE D C     1 
ATOM   5641 O O     . PHE B 2 308 ? 125.948 138.774 89.922  1.00 89.90  ? 308 PHE D O     1 
ATOM   5642 C CB    . PHE B 2 308 ? 125.983 135.677 89.357  1.00 125.40 ? 308 PHE D CB    1 
ATOM   5643 C CG    . PHE B 2 308 ? 125.551 134.315 89.268  1.00 125.40 ? 308 PHE D CG    1 
ATOM   5644 C CD1   . PHE B 2 308 ? 124.595 133.930 88.412  1.00 125.40 ? 308 PHE D CD1   1 
ATOM   5645 C CD2   . PHE B 2 308 ? 126.195 133.391 89.966  1.00 125.40 ? 308 PHE D CD2   1 
ATOM   5646 C CE1   . PHE B 2 308 ? 124.265 132.638 88.322  1.00 125.40 ? 308 PHE D CE1   1 
ATOM   5647 C CE2   . PHE B 2 308 ? 125.865 132.120 89.867  1.00 125.40 ? 308 PHE D CE2   1 
ATOM   5648 C CZ    . PHE B 2 308 ? 124.898 131.744 89.049  1.00 125.40 ? 308 PHE D CZ    1 
ATOM   5649 N N     . THR B 2 309 ? 126.853 137.599 91.578  1.00 90.59  ? 309 THR D N     1 
ATOM   5650 C CA    . THR B 2 309 ? 127.885 138.542 91.871  1.00 90.59  ? 309 THR D CA    1 
ATOM   5651 C C     . THR B 2 309 ? 129.224 137.914 91.641  1.00 90.59  ? 309 THR D C     1 
ATOM   5652 O O     . THR B 2 309 ? 130.173 138.589 91.256  1.00 90.59  ? 309 THR D O     1 
ATOM   5653 C CB    . THR B 2 309 ? 127.771 139.012 93.312  1.00 126.81 ? 309 THR D CB    1 
ATOM   5654 O OG1   . THR B 2 309 ? 126.497 139.620 93.514  1.00 126.81 ? 309 THR D OG1   1 
ATOM   5655 C CG2   . THR B 2 309 ? 128.831 140.006 93.626  1.00 126.81 ? 309 THR D CG2   1 
ATOM   5656 N N     . ALA B 2 310 ? 129.309 136.617 91.828  1.00 87.61  ? 310 ALA D N     1 
ATOM   5657 C CA    . ALA B 2 310 ? 130.549 135.933 91.585  1.00 87.61  ? 310 ALA D CA    1 
ATOM   5658 C C     . ALA B 2 310 ? 130.251 134.497 91.254  1.00 87.61  ? 310 ALA D C     1 
ATOM   5659 O O     . ALA B 2 310 ? 129.296 133.926 91.757  1.00 87.61  ? 310 ALA D O     1 
ATOM   5660 C CB    . ALA B 2 310 ? 131.449 136.019 92.788  1.00 119.47 ? 310 ALA D CB    1 
ATOM   5661 N N     . PHE B 2 311 ? 131.095 133.886 90.457  1.00 85.97  ? 311 PHE D N     1 
ATOM   5662 C CA    . PHE B 2 311 ? 130.830 132.512 90.076  1.00 85.97  ? 311 PHE D CA    1 
ATOM   5663 C C     . PHE B 2 311 ? 132.111 131.847 89.687  1.00 85.97  ? 311 PHE D C     1 
ATOM   5664 O O     . PHE B 2 311 ? 132.745 132.249 88.713  1.00 85.97  ? 311 PHE D O     1 
ATOM   5665 C CB    . PHE B 2 311 ? 129.861 132.519 88.949  1.00 119.91 ? 311 PHE D CB    1 
ATOM   5666 C CG    . PHE B 2 311 ? 129.379 131.227 88.469  1.00 119.91 ? 311 PHE D CG    1 
ATOM   5667 C CD1   . PHE B 2 311 ? 129.557 130.052 89.087  1.00 119.91 ? 311 PHE D CD1   1 
ATOM   5668 C CD2   . PHE B 2 311 ? 128.625 131.241 87.353  1.00 119.91 ? 311 PHE D CD2   1 
ATOM   5669 C CE1   . PHE B 2 311 ? 129.018 128.912 88.542  1.00 119.91 ? 311 PHE D CE1   1 
ATOM   5670 C CE2   . PHE B 2 311 ? 128.105 130.125 86.821  1.00 119.91 ? 311 PHE D CE2   1 
ATOM   5671 C CZ    . PHE B 2 311 ? 128.299 128.962 87.410  1.00 119.91 ? 311 PHE D CZ    1 
ATOM   5672 N N     . VAL B 2 312 ? 132.510 130.862 90.448  1.00 84.05  ? 312 VAL D N     1 
ATOM   5673 C CA    . VAL B 2 312 ? 133.747 130.159 90.203  1.00 84.05  ? 312 VAL D CA    1 
ATOM   5674 C C     . VAL B 2 312 ? 133.472 128.700 89.985  1.00 84.05  ? 312 VAL D C     1 
ATOM   5675 O O     . VAL B 2 312 ? 132.862 128.048 90.831  1.00 84.05  ? 312 VAL D O     1 
ATOM   5676 C CB    . VAL B 2 312 ? 134.707 130.339 91.356  1.00 122.21 ? 312 VAL D CB    1 
ATOM   5677 C CG1   . VAL B 2 312 ? 135.946 129.578 91.079  1.00 122.21 ? 312 VAL D CG1   1 
ATOM   5678 C CG2   . VAL B 2 312 ? 135.005 131.805 91.517  1.00 122.21 ? 312 VAL D CG2   1 
ATOM   5679 N N     . ILE B 2 313 ? 133.925 128.178 88.881  1.00 84.72  ? 313 ILE D N     1 
ATOM   5680 C CA    . ILE B 2 313 ? 133.759 126.783 88.569  1.00 84.72  ? 313 ILE D CA    1 
ATOM   5681 C C     . ILE B 2 313 ? 135.090 126.102 88.750  1.00 84.72  ? 313 ILE D C     1 
ATOM   5682 O O     . ILE B 2 313 ? 136.035 126.364 88.013  1.00 84.72  ? 313 ILE D O     1 
ATOM   5683 C CB    . ILE B 2 313 ? 133.239 126.587 87.158  1.00 125.35 ? 313 ILE D CB    1 
ATOM   5684 C CG1   . ILE B 2 313 ? 131.919 127.298 87.001  1.00 125.35 ? 313 ILE D CG1   1 
ATOM   5685 C CG2   . ILE B 2 313 ? 133.135 125.149 86.858  1.00 125.35 ? 313 ILE D CG2   1 
ATOM   5686 C CD1   . ILE B 2 313 ? 131.399 127.352 85.584  1.00 125.35 ? 313 ILE D CD1   1 
ATOM   5687 N N     . ALA B 2 314 ? 135.182 125.234 89.713  1.00 88.10  ? 314 ALA D N     1 
ATOM   5688 C CA    . ALA B 2 314 ? 136.430 124.577 90.022  1.00 88.10  ? 314 ALA D CA    1 
ATOM   5689 C C     . ALA B 2 314 ? 136.294 123.127 89.651  1.00 88.10  ? 314 ALA D C     1 
ATOM   5690 O O     . ALA B 2 314 ? 135.556 122.379 90.292  1.00 88.10  ? 314 ALA D O     1 
ATOM   5691 C CB    . ALA B 2 314 ? 136.759 124.732 91.487  1.00 120.14 ? 314 ALA D CB    1 
ATOM   5692 N N     . LEU B 2 315 ? 136.971 122.728 88.612  1.00 89.63  ? 315 LEU D N     1 
ATOM   5693 C CA    . LEU B 2 315 ? 136.824 121.372 88.170  1.00 89.63  ? 315 LEU D CA    1 
ATOM   5694 C C     . LEU B 2 315 ? 138.028 120.565 88.561  1.00 89.63  ? 315 LEU D C     1 
ATOM   5695 O O     . LEU B 2 315 ? 139.064 121.092 88.937  1.00 89.63  ? 315 LEU D O     1 
ATOM   5696 C CB    . LEU B 2 315 ? 136.615 121.324 86.676  1.00 132.62 ? 315 LEU D CB    1 
ATOM   5697 C CG    . LEU B 2 315 ? 135.455 122.144 86.163  1.00 132.62 ? 315 LEU D CG    1 
ATOM   5698 C CD1   . LEU B 2 315 ? 135.400 121.997 84.737  1.00 132.62 ? 315 LEU D CD1   1 
ATOM   5699 C CD2   . LEU B 2 315 ? 134.174 121.695 86.756  1.00 132.62 ? 315 LEU D CD2   1 
ATOM   5700 N N     . ARG B 2 316 ? 137.859 119.273 88.542  1.00 94.67  ? 316 ARG D N     1 
ATOM   5701 C CA    . ARG B 2 316 ? 138.924 118.351 88.852  1.00 94.67  ? 316 ARG D CA    1 
ATOM   5702 C C     . ARG B 2 316 ? 139.111 117.420 87.670  1.00 94.67  ? 316 ARG D C     1 
ATOM   5703 O O     . ARG B 2 316 ? 138.141 116.987 87.052  1.00 94.67  ? 316 ARG D O     1 
ATOM   5704 C CB    . ARG B 2 316 ? 138.572 117.499 90.044  1.00 138.99 ? 316 ARG D CB    1 
ATOM   5705 C CG    . ARG B 2 316 ? 138.090 118.159 91.293  1.00 138.99 ? 316 ARG D CG    1 
ATOM   5706 C CD    . ARG B 2 316 ? 139.156 118.837 92.017  1.00 138.99 ? 316 ARG D CD    1 
ATOM   5707 N NE    . ARG B 2 316 ? 140.217 117.936 92.438  1.00 138.99 ? 316 ARG D NE    1 
ATOM   5708 C CZ    . ARG B 2 316 ? 140.216 117.194 93.536  1.00 138.99 ? 316 ARG D CZ    1 
ATOM   5709 N NH1   . ARG B 2 316 ? 139.169 117.129 94.324  1.00 138.99 ? 316 ARG D NH1   1 
ATOM   5710 N NH2   . ARG B 2 316 ? 141.309 116.515 93.845  1.00 138.99 ? 316 ARG D NH2   1 
ATOM   5711 N N     . GLY B 2 317 ? 140.339 117.037 87.411  1.00 95.09  ? 317 GLY D N     1 
ATOM   5712 C CA    . GLY B 2 317 ? 140.594 116.071 86.379  1.00 95.09  ? 317 GLY D CA    1 
ATOM   5713 C C     . GLY B 2 317 ? 140.757 116.740 85.042  1.00 95.09  ? 317 GLY D C     1 
ATOM   5714 O O     . GLY B 2 317 ? 140.879 117.950 84.942  1.00 95.09  ? 317 GLY D O     1 
ATOM   5715 N N     . GLU B 2 318 ? 140.748 115.941 83.988  1.00 95.72  ? 318 GLU D N     1 
ATOM   5716 C CA    . GLU B 2 318 ? 141.035 116.480 82.674  1.00 95.72  ? 318 GLU D CA    1 
ATOM   5717 C C     . GLU B 2 318 ? 139.823 117.196 82.108  1.00 95.72  ? 318 GLU D C     1 
ATOM   5718 O O     . GLU B 2 318 ? 138.813 116.577 81.763  1.00 95.72  ? 318 GLU D O     1 
ATOM   5719 C CB    . GLU B 2 318 ? 141.481 115.383 81.732  1.00 128.57 ? 318 GLU D CB    1 
ATOM   5720 C CG    . GLU B 2 318 ? 141.847 115.873 80.360  1.00 128.57 ? 318 GLU D CG    1 
ATOM   5721 C CD    . GLU B 2 318 ? 142.295 114.767 79.467  1.00 128.57 ? 318 GLU D CD    1 
ATOM   5722 O OE1   . GLU B 2 318 ? 142.270 113.617 79.902  1.00 128.57 ? 318 GLU D OE1   1 
ATOM   5723 O OE2   . GLU B 2 318 ? 142.679 115.040 78.331  1.00 128.57 ? 318 GLU D OE2   1 
ATOM   5724 N N     . ASN B 2 319 ? 139.984 118.505 81.955  1.00 97.26  ? 319 ASN D N     1 
ATOM   5725 C CA    . ASN B 2 319 ? 138.952 119.412 81.478  1.00 97.26  ? 319 ASN D CA    1 
ATOM   5726 C C     . ASN B 2 319 ? 139.600 120.412 80.548  1.00 97.26  ? 319 ASN D C     1 
ATOM   5727 O O     . ASN B 2 319 ? 140.032 121.479 80.976  1.00 97.26  ? 319 ASN D O     1 
ATOM   5728 C CB    . ASN B 2 319 ? 138.301 120.113 82.649  1.00 131.76 ? 319 ASN D CB    1 
ATOM   5729 C CG    . ASN B 2 319 ? 137.519 119.190 83.498  1.00 131.76 ? 319 ASN D CG    1 
ATOM   5730 O OD1   . ASN B 2 319 ? 136.347 118.962 83.243  1.00 131.76 ? 319 ASN D OD1   1 
ATOM   5731 N ND2   . ASN B 2 319 ? 138.142 118.654 84.528  1.00 131.76 ? 319 ASN D ND2   1 
ATOM   5732 N N     . PRO B 2 320 ? 139.732 120.076 79.279  1.00 99.85  ? 320 PRO D N     1 
ATOM   5733 C CA    . PRO B 2 320 ? 140.398 120.934 78.312  1.00 99.85  ? 320 PRO D CA    1 
ATOM   5734 C C     . PRO B 2 320 ? 139.707 122.272 78.307  1.00 99.85  ? 320 PRO D C     1 
ATOM   5735 O O     . PRO B 2 320 ? 138.484 122.345 78.411  1.00 99.85  ? 320 PRO D O     1 
ATOM   5736 C CB    . PRO B 2 320 ? 140.184 120.187 77.008  1.00 311.44 ? 320 PRO D CB    1 
ATOM   5737 C CG    . PRO B 2 320 ? 139.990 118.802 77.436  1.00 311.44 ? 320 PRO D CG    1 
ATOM   5738 C CD    . PRO B 2 320 ? 139.229 118.862 78.695  1.00 311.44 ? 320 PRO D CD    1 
ATOM   5739 N N     . HIS B 2 321 ? 140.481 123.332 78.193  1.00 98.16  ? 321 HIS D N     1 
ATOM   5740 C CA    . HIS B 2 321 ? 139.909 124.657 78.291  1.00 98.16  ? 321 HIS D CA    1 
ATOM   5741 C C     . HIS B 2 321 ? 139.141 125.069 77.058  1.00 98.16  ? 321 HIS D C     1 
ATOM   5742 O O     . HIS B 2 321 ? 138.335 125.989 77.133  1.00 98.16  ? 321 HIS D O     1 
ATOM   5743 C CB    . HIS B 2 321 ? 141.017 125.611 78.530  1.00 133.47 ? 321 HIS D CB    1 
ATOM   5744 C CG    . HIS B 2 321 ? 142.037 125.466 77.497  1.00 133.47 ? 321 HIS D CG    1 
ATOM   5745 N ND1   . HIS B 2 321 ? 142.834 124.348 77.413  1.00 133.47 ? 321 HIS D ND1   1 
ATOM   5746 C CD2   . HIS B 2 321 ? 142.347 126.243 76.440  1.00 133.47 ? 321 HIS D CD2   1 
ATOM   5747 C CE1   . HIS B 2 321 ? 143.627 124.463 76.364  1.00 133.47 ? 321 HIS D CE1   1 
ATOM   5748 N NE2   . HIS B 2 321 ? 143.351 125.604 75.757  1.00 133.47 ? 321 HIS D NE2   1 
ATOM   5749 N N     . SER B 2 322 ? 139.372 124.447 75.930  1.00 97.30  ? 322 SER D N     1 
ATOM   5750 C CA    . SER B 2 322 ? 138.613 124.840 74.768  1.00 97.30  ? 322 SER D CA    1 
ATOM   5751 C C     . SER B 2 322 ? 137.176 124.444 74.936  1.00 97.30  ? 322 SER D C     1 
ATOM   5752 O O     . SER B 2 322 ? 136.261 125.174 74.524  1.00 97.30  ? 322 SER D O     1 
ATOM   5753 C CB    . SER B 2 322 ? 139.174 124.184 73.537  1.00 131.05 ? 322 SER D CB    1 
ATOM   5754 O OG    . SER B 2 322 ? 138.962 122.796 73.611  1.00 131.05 ? 322 SER D OG    1 
ATOM   5755 N N     . ILE B 2 323 ? 136.962 123.313 75.589  1.00 98.52  ? 323 ILE D N     1 
ATOM   5756 C CA    . ILE B 2 323 ? 135.615 122.862 75.843  1.00 98.52  ? 323 ILE D CA    1 
ATOM   5757 C C     . ILE B 2 323 ? 134.979 123.714 76.888  1.00 98.52  ? 323 ILE D C     1 
ATOM   5758 O O     . ILE B 2 323 ? 133.818 124.089 76.761  1.00 98.52  ? 323 ILE D O     1 
ATOM   5759 C CB    . ILE B 2 323 ? 135.569 121.415 76.280  1.00 145.77 ? 323 ILE D CB    1 
ATOM   5760 C CG1   . ILE B 2 323 ? 136.065 120.547 75.157  1.00 145.77 ? 323 ILE D CG1   1 
ATOM   5761 C CG2   . ILE B 2 323 ? 134.128 121.073 76.685  1.00 145.77 ? 323 ILE D CG2   1 
ATOM   5762 C CD1   . ILE B 2 323 ? 136.318 119.110 75.559  1.00 145.77 ? 323 ILE D CD1   1 
ATOM   5763 N N     . LEU B 2 324 ? 135.705 124.017 77.947  1.00 98.27  ? 324 LEU D N     1 
ATOM   5764 C CA    . LEU B 2 324 ? 135.108 124.803 78.998  1.00 98.27  ? 324 LEU D CA    1 
ATOM   5765 C C     . LEU B 2 324 ? 134.680 126.143 78.459  1.00 98.27  ? 324 LEU D C     1 
ATOM   5766 O O     . LEU B 2 324 ? 133.591 126.628 78.770  1.00 98.27  ? 324 LEU D O     1 
ATOM   5767 C CB    . LEU B 2 324 ? 136.089 125.003 80.144  1.00 145.40 ? 324 LEU D CB    1 
ATOM   5768 C CG    . LEU B 2 324 ? 136.605 123.785 80.879  1.00 145.40 ? 324 LEU D CG    1 
ATOM   5769 C CD1   . LEU B 2 324 ? 137.636 124.200 81.911  1.00 145.40 ? 324 LEU D CD1   1 
ATOM   5770 C CD2   . LEU B 2 324 ? 135.494 123.031 81.508  1.00 145.40 ? 324 LEU D CD2   1 
ATOM   5771 N N     . GLN B 2 325 ? 135.509 126.754 77.636  1.00 100.54 ? 325 GLN D N     1 
ATOM   5772 C CA    . GLN B 2 325 ? 135.165 128.069 77.128  1.00 100.54 ? 325 GLN D CA    1 
ATOM   5773 C C     . GLN B 2 325 ? 133.992 128.021 76.171  1.00 100.54 ? 325 GLN D C     1 
ATOM   5774 O O     . GLN B 2 325 ? 133.208 128.958 76.129  1.00 100.54 ? 325 GLN D O     1 
ATOM   5775 C CB    . GLN B 2 325 ? 136.351 128.700 76.447  1.00 140.45 ? 325 GLN D CB    1 
ATOM   5776 C CG    . GLN B 2 325 ? 136.093 130.095 76.014  1.00 140.45 ? 325 GLN D CG    1 
ATOM   5777 C CD    . GLN B 2 325 ? 135.800 130.976 77.182  1.00 140.45 ? 325 GLN D CD    1 
ATOM   5778 O OE1   . GLN B 2 325 ? 136.536 130.973 78.166  1.00 140.45 ? 325 GLN D OE1   1 
ATOM   5779 N NE2   . GLN B 2 325 ? 134.721 131.748 77.095  1.00 140.45 ? 325 GLN D NE2   1 
ATOM   5780 N N     . ASN B 2 326 ? 133.863 126.985 75.365  1.00 94.38  ? 326 ASN D N     1 
ATOM   5781 C CA    . ASN B 2 326 ? 132.693 126.974 74.505  1.00 94.38  ? 326 ASN D CA    1 
ATOM   5782 C C     . ASN B 2 326 ? 131.447 126.588 75.254  1.00 94.38  ? 326 ASN D C     1 
ATOM   5783 O O     . ASN B 2 326 ? 130.370 127.109 74.985  1.00 94.38  ? 326 ASN D O     1 
ATOM   5784 C CB    . ASN B 2 326 ? 132.907 126.026 73.356  1.00 127.86 ? 326 ASN D CB    1 
ATOM   5785 C CG    . ASN B 2 326 ? 133.897 126.561 72.361  1.00 127.86 ? 326 ASN D CG    1 
ATOM   5786 O OD1   . ASN B 2 326 ? 134.108 127.773 72.254  1.00 127.86 ? 326 ASN D OD1   1 
ATOM   5787 N ND2   . ASN B 2 326 ? 134.512 125.666 71.620  1.00 127.86 ? 326 ASN D ND2   1 
ATOM   5788 N N     . SER B 2 327 ? 131.589 125.717 76.222  1.00 95.96  ? 327 SER D N     1 
ATOM   5789 C CA    . SER B 2 327 ? 130.455 125.248 76.996  1.00 95.96  ? 327 SER D CA    1 
ATOM   5790 C C     . SER B 2 327 ? 129.804 126.372 77.761  1.00 95.96  ? 327 SER D C     1 
ATOM   5791 O O     . SER B 2 327 ? 128.576 126.464 77.801  1.00 95.96  ? 327 SER D O     1 
ATOM   5792 C CB    . SER B 2 327 ? 130.922 124.177 77.953  1.00 129.25 ? 327 SER D CB    1 
ATOM   5793 O OG    . SER B 2 327 ? 129.857 123.700 78.723  1.00 129.25 ? 327 SER D OG    1 
ATOM   5794 N N     . ILE B 2 328 ? 130.610 127.274 78.318  1.00 94.13  ? 328 ILE D N     1 
ATOM   5795 C CA    . ILE B 2 328 ? 130.147 128.399 79.127  1.00 94.13  ? 328 ILE D CA    1 
ATOM   5796 C C     . ILE B 2 328 ? 129.214 129.306 78.357  1.00 94.13  ? 328 ILE D C     1 
ATOM   5797 O O     . ILE B 2 328 ? 128.461 130.064 78.952  1.00 94.13  ? 328 ILE D O     1 
ATOM   5798 C CB    . ILE B 2 328 ? 131.342 129.233 79.610  1.00 139.28 ? 328 ILE D CB    1 
ATOM   5799 C CG1   . ILE B 2 328 ? 131.047 129.963 80.896  1.00 139.28 ? 328 ILE D CG1   1 
ATOM   5800 C CG2   . ILE B 2 328 ? 131.666 130.303 78.617  1.00 139.28 ? 328 ILE D CG2   1 
ATOM   5801 C CD1   . ILE B 2 328 ? 130.997 129.067 82.090  1.00 139.28 ? 328 ILE D CD1   1 
ATOM   5802 N N     . LYS B 2 329 ? 129.250 129.274 77.041  1.00 90.53  ? 329 LYS D N     1 
ATOM   5803 C CA    . LYS B 2 329 ? 128.376 130.132 76.277  1.00 90.53  ? 329 LYS D CA    1 
ATOM   5804 C C     . LYS B 2 329 ? 126.950 129.647 76.339  1.00 90.53  ? 329 LYS D C     1 
ATOM   5805 O O     . LYS B 2 329 ? 126.024 130.399 76.048  1.00 90.53  ? 329 LYS D O     1 
ATOM   5806 C CB    . LYS B 2 329 ? 128.843 130.198 74.837  1.00 135.67 ? 329 LYS D CB    1 
ATOM   5807 C CG    . LYS B 2 329 ? 130.190 130.860 74.665  1.00 135.67 ? 329 LYS D CG    1 
ATOM   5808 C CD    . LYS B 2 329 ? 130.597 130.892 73.204  1.00 135.67 ? 329 LYS D CD    1 
ATOM   5809 C CE    . LYS B 2 329 ? 131.983 131.490 73.016  1.00 135.67 ? 329 LYS D CE    1 
ATOM   5810 N NZ    . LYS B 2 329 ? 132.371 131.557 71.574  1.00 135.67 ? 329 LYS D NZ    1 
ATOM   5811 N N     . GLY B 2 330 ? 126.755 128.424 76.750  1.00 90.03  ? 330 GLY D N     1 
ATOM   5812 C CA    . GLY B 2 330 ? 125.438 127.860 76.882  1.00 90.03  ? 330 GLY D CA    1 
ATOM   5813 C C     . GLY B 2 330 ? 124.727 128.373 78.096  1.00 90.03  ? 330 GLY D C     1 
ATOM   5814 O O     . GLY B 2 330 ? 123.564 128.081 78.351  1.00 90.03  ? 330 GLY D O     1 
ATOM   5815 N N     . PHE B 2 331 ? 125.432 129.129 78.875  1.00 93.78  ? 331 PHE D N     1 
ATOM   5816 C CA    . PHE B 2 331 ? 124.881 129.717 80.043  1.00 93.78  ? 331 PHE D CA    1 
ATOM   5817 C C     . PHE B 2 331 ? 124.387 131.114 79.721  1.00 93.78  ? 331 PHE D C     1 
ATOM   5818 O O     . PHE B 2 331 ? 123.933 131.832 80.614  1.00 93.78  ? 331 PHE D O     1 
ATOM   5819 C CB    . PHE B 2 331 ? 125.946 129.811 81.145  1.00 130.81 ? 331 PHE D CB    1 
ATOM   5820 C CG    . PHE B 2 331 ? 126.546 128.513 81.662  1.00 130.81 ? 331 PHE D CG    1 
ATOM   5821 C CD1   . PHE B 2 331 ? 126.217 127.276 81.216  1.00 130.81 ? 331 PHE D CD1   1 
ATOM   5822 C CD2   . PHE B 2 331 ? 127.454 128.605 82.686  1.00 130.81 ? 331 PHE D CD2   1 
ATOM   5823 C CE1   . PHE B 2 331 ? 126.809 126.177 81.786  1.00 130.81 ? 331 PHE D CE1   1 
ATOM   5824 C CE2   . PHE B 2 331 ? 128.024 127.522 83.239  1.00 130.81 ? 331 PHE D CE2   1 
ATOM   5825 C CZ    . PHE B 2 331 ? 127.707 126.314 82.796  1.00 130.81 ? 331 PHE D CZ    1 
ATOM   5826 N N     . GLY B 2 332 ? 124.454 131.519 78.459  1.00 94.63  ? 332 GLY D N     1 
ATOM   5827 C CA    . GLY B 2 332 ? 124.111 132.894 78.106  1.00 94.63  ? 332 GLY D CA    1 
ATOM   5828 C C     . GLY B 2 332 ? 122.706 133.331 78.493  1.00 94.63  ? 332 GLY D C     1 
ATOM   5829 O O     . GLY B 2 332 ? 122.469 134.498 78.785  1.00 94.63  ? 332 GLY D O     1 
ATOM   5830 N N     . ASP B 2 333 ? 121.761 132.426 78.491  1.00 94.42  ? 333 ASP D N     1 
ATOM   5831 C CA    . ASP B 2 333 ? 120.408 132.780 78.845  1.00 94.42  ? 333 ASP D CA    1 
ATOM   5832 C C     . ASP B 2 333 ? 120.101 132.511 80.298  1.00 94.42  ? 333 ASP D C     1 
ATOM   5833 O O     . ASP B 2 333 ? 118.950 132.607 80.705  1.00 94.42  ? 333 ASP D O     1 
ATOM   5834 C CB    . ASP B 2 333 ? 119.436 131.998 77.982  1.00 121.40 ? 333 ASP D CB    1 
ATOM   5835 C CG    . ASP B 2 333 ? 119.554 132.328 76.518  1.00 121.40 ? 333 ASP D CG    1 
ATOM   5836 O OD1   . ASP B 2 333 ? 119.782 133.489 76.175  1.00 121.40 ? 333 ASP D OD1   1 
ATOM   5837 O OD2   . ASP B 2 333 ? 119.421 131.414 75.702  1.00 121.40 ? 333 ASP D OD2   1 
ATOM   5838 N N     . ARG B 2 334 ? 121.078 132.090 81.064  1.00 90.42  ? 334 ARG D N     1 
ATOM   5839 C CA    . ARG B 2 334 ? 120.833 131.741 82.437  1.00 90.42  ? 334 ARG D CA    1 
ATOM   5840 C C     . ARG B 2 334 ? 121.726 132.483 83.393  1.00 90.42  ? 334 ARG D C     1 
ATOM   5841 O O     . ARG B 2 334 ? 121.268 133.036 84.386  1.00 90.42  ? 334 ARG D O     1 
ATOM   5842 C CB    . ARG B 2 334 ? 121.002 130.252 82.618  1.00 132.75 ? 334 ARG D CB    1 
ATOM   5843 C CG    . ARG B 2 334 ? 119.918 129.445 81.919  1.00 132.75 ? 334 ARG D CG    1 
ATOM   5844 C CD    . ARG B 2 334 ? 120.110 127.952 82.053  1.00 132.75 ? 334 ARG D CD    1 
ATOM   5845 N NE    . ARG B 2 334 ? 121.175 127.456 81.195  1.00 132.75 ? 334 ARG D NE    1 
ATOM   5846 C CZ    . ARG B 2 334 ? 121.645 126.216 81.215  1.00 132.75 ? 334 ARG D CZ    1 
ATOM   5847 N NH1   . ARG B 2 334 ? 121.171 125.323 82.059  1.00 132.75 ? 334 ARG D NH1   1 
ATOM   5848 N NH2   . ARG B 2 334 ? 122.615 125.872 80.365  1.00 132.75 ? 334 ARG D NH2   1 
ATOM   5849 N N     . VAL B 2 335 ? 123.009 132.502 83.152  1.00 90.25  ? 335 VAL D N     1 
ATOM   5850 C CA    . VAL B 2 335 ? 123.867 133.041 84.151  1.00 90.25  ? 335 VAL D CA    1 
ATOM   5851 C C     . VAL B 2 335 ? 124.061 134.512 83.886  1.00 90.25  ? 335 VAL D C     1 
ATOM   5852 O O     . VAL B 2 335 ? 124.897 134.902 83.081  1.00 90.25  ? 335 VAL D O     1 
ATOM   5853 C CB    . VAL B 2 335 ? 125.172 132.309 84.184  1.00 131.23 ? 335 VAL D CB    1 
ATOM   5854 C CG1   . VAL B 2 335 ? 126.068 132.938 85.200  1.00 131.23 ? 335 VAL D CG1   1 
ATOM   5855 C CG2   . VAL B 2 335 ? 124.860 130.939 84.542  1.00 131.23 ? 335 VAL D CG2   1 
ATOM   5856 N N     . LYS B 2 336 ? 123.327 135.325 84.636  1.00 94.60  ? 336 LYS D N     1 
ATOM   5857 C CA    . LYS B 2 336 ? 123.317 136.762 84.482  1.00 94.60  ? 336 LYS D CA    1 
ATOM   5858 C C     . LYS B 2 336 ? 123.885 137.458 85.702  1.00 94.60  ? 336 LYS D C     1 
ATOM   5859 O O     . LYS B 2 336 ? 123.418 137.221 86.808  1.00 94.60  ? 336 LYS D O     1 
ATOM   5860 C CB    . LYS B 2 336 ? 121.886 137.173 84.268  1.00 141.77 ? 336 LYS D CB    1 
ATOM   5861 C CG    . LYS B 2 336 ? 120.909 136.228 84.899  1.00 141.77 ? 336 LYS D CG    1 
ATOM   5862 C CD    . LYS B 2 336 ? 119.509 136.536 84.457  1.00 141.77 ? 336 LYS D CD    1 
ATOM   5863 C CE    . LYS B 2 336 ? 119.427 136.523 82.954  1.00 141.77 ? 336 LYS D CE    1 
ATOM   5864 N NZ    . LYS B 2 336 ? 118.043 136.777 82.462  1.00 141.77 ? 336 LYS D NZ    1 
ATOM   5865 N N     . PHE B 2 337 ? 124.862 138.314 85.510  1.00 93.25  ? 337 PHE D N     1 
ATOM   5866 C CA    . PHE B 2 337 ? 125.498 139.021 86.598  1.00 93.25  ? 337 PHE D CA    1 
ATOM   5867 C C     . PHE B 2 337 ? 124.879 140.388 86.734  1.00 93.25  ? 337 PHE D C     1 
ATOM   5868 O O     . PHE B 2 337 ? 124.463 140.983 85.745  1.00 93.25  ? 337 PHE D O     1 
ATOM   5869 C CB    . PHE B 2 337 ? 126.973 139.153 86.336  1.00 130.07 ? 337 PHE D CB    1 
ATOM   5870 C CG    . PHE B 2 337 ? 127.685 137.884 86.416  1.00 130.07 ? 337 PHE D CG    1 
ATOM   5871 C CD1   . PHE B 2 337 ? 127.802 137.082 85.343  1.00 130.07 ? 337 PHE D CD1   1 
ATOM   5872 C CD2   . PHE B 2 337 ? 128.246 137.498 87.592  1.00 130.07 ? 337 PHE D CD2   1 
ATOM   5873 C CE1   . PHE B 2 337 ? 128.476 135.917 85.438  1.00 130.07 ? 337 PHE D CE1   1 
ATOM   5874 C CE2   . PHE B 2 337 ? 128.914 136.331 87.693  1.00 130.07 ? 337 PHE D CE2   1 
ATOM   5875 C CZ    . PHE B 2 337 ? 129.030 135.541 86.618  1.00 130.07 ? 337 PHE D CZ    1 
ATOM   5876 N N     . SER B 2 338 ? 124.801 140.882 87.951  1.00 95.26  ? 338 SER D N     1 
ATOM   5877 C CA    . SER B 2 338 ? 124.230 142.203 88.138  1.00 95.26  ? 338 SER D CA    1 
ATOM   5878 C C     . SER B 2 338 ? 125.212 143.279 87.732  1.00 95.26  ? 338 SER D C     1 
ATOM   5879 O O     . SER B 2 338 ? 126.400 143.203 88.040  1.00 95.26  ? 338 SER D O     1 
ATOM   5880 C CB    . SER B 2 338 ? 123.804 142.411 89.577  1.00 128.31 ? 338 SER D CB    1 
ATOM   5881 O OG    . SER B 2 338 ? 123.333 143.726 89.743  1.00 128.31 ? 338 SER D OG    1 
ATOM   5882 N N     . GLU B 2 339 ? 124.711 144.315 87.079  1.00 96.17  ? 339 GLU D N     1 
ATOM   5883 C CA    . GLU B 2 339 ? 125.573 145.354 86.526  1.00 96.17  ? 339 GLU D CA    1 
ATOM   5884 C C     . GLU B 2 339 ? 125.969 146.382 87.566  1.00 96.17  ? 339 GLU D C     1 
ATOM   5885 O O     . GLU B 2 339 ? 125.700 147.572 87.457  1.00 96.17  ? 339 GLU D O     1 
ATOM   5886 C CB    . GLU B 2 339 ? 124.897 146.050 85.366  1.00 129.17 ? 339 GLU D CB    1 
ATOM   5887 C CG    . GLU B 2 339 ? 124.651 145.153 84.193  1.00 129.17 ? 339 GLU D CG    1 
ATOM   5888 C CD    . GLU B 2 339 ? 124.008 145.866 83.039  1.00 129.17 ? 339 GLU D CD    1 
ATOM   5889 O OE1   . GLU B 2 339 ? 123.685 147.045 83.173  1.00 129.17 ? 339 GLU D OE1   1 
ATOM   5890 O OE2   . GLU B 2 339 ? 123.824 145.243 81.993  1.00 129.17 ? 339 GLU D OE2   1 
ATOM   5891 N N     . ILE B 2 340 ? 126.590 145.869 88.608  1.00 97.62  ? 340 ILE D N     1 
ATOM   5892 C CA    . ILE B 2 340 ? 127.203 146.654 89.658  1.00 97.62  ? 340 ILE D CA    1 
ATOM   5893 C C     . ILE B 2 340 ? 128.596 146.178 89.804  1.00 97.62  ? 340 ILE D C     1 
ATOM   5894 O O     . ILE B 2 340 ? 129.443 146.816 90.431  1.00 97.62  ? 340 ILE D O     1 
ATOM   5895 C CB    . ILE B 2 340 ? 126.402 146.463 90.965  1.00 144.44 ? 340 ILE D CB    1 
ATOM   5896 C CG1   . ILE B 2 340 ? 126.478 144.979 91.436  1.00 144.44 ? 340 ILE D CG1   1 
ATOM   5897 C CG2   . ILE B 2 340 ? 124.946 146.867 90.727  1.00 144.44 ? 340 ILE D CG2   1 
ATOM   5898 C CD1   . ILE B 2 340 ? 125.928 144.693 92.830  1.00 144.44 ? 340 ILE D CD1   1 
ATOM   5899 N N     . PHE B 2 341 ? 128.836 145.035 89.178  1.00 101.24 ? 341 PHE D N     1 
ATOM   5900 C CA    . PHE B 2 341 ? 130.102 144.341 89.284  1.00 101.24 ? 341 PHE D CA    1 
ATOM   5901 C C     . PHE B 2 341 ? 130.395 143.630 87.968  1.00 101.24 ? 341 PHE D C     1 
ATOM   5902 O O     . PHE B 2 341 ? 129.838 142.558 87.692  1.00 101.24 ? 341 PHE D O     1 
ATOM   5903 C CB    . PHE B 2 341 ? 130.013 143.381 90.449  1.00 141.21 ? 341 PHE D CB    1 
ATOM   5904 C CG    . PHE B 2 341 ? 131.272 142.754 90.779  1.00 141.21 ? 341 PHE D CG    1 
ATOM   5905 C CD1   . PHE B 2 341 ? 132.354 143.508 91.177  1.00 141.21 ? 341 PHE D CD1   1 
ATOM   5906 C CD2   . PHE B 2 341 ? 131.383 141.394 90.724  1.00 141.21 ? 341 PHE D CD2   1 
ATOM   5907 C CE1   . PHE B 2 341 ? 133.539 142.898 91.500  1.00 141.21 ? 341 PHE D CE1   1 
ATOM   5908 C CE2   . PHE B 2 341 ? 132.555 140.778 91.048  1.00 141.21 ? 341 PHE D CE2   1 
ATOM   5909 C CZ    . PHE B 2 341 ? 133.639 141.526 91.433  1.00 141.21 ? 341 PHE D CZ    1 
ATOM   5910 N N     . PRO B 2 342 ? 131.260 144.178 87.152  1.00 103.08 ? 342 PRO D N     1 
ATOM   5911 C CA    . PRO B 2 342 ? 131.540 143.723 85.785  1.00 103.08 ? 342 PRO D CA    1 
ATOM   5912 C C     . PRO B 2 342 ? 132.430 142.491 85.758  1.00 103.08 ? 342 PRO D C     1 
ATOM   5913 O O     . PRO B 2 342 ? 133.587 142.547 85.326  1.00 103.08 ? 342 PRO D O     1 
ATOM   5914 C CB    . PRO B 2 342 ? 132.247 144.937 85.183  1.00 321.51 ? 342 PRO D CB    1 
ATOM   5915 C CG    . PRO B 2 342 ? 132.988 145.533 86.356  1.00 321.51 ? 342 PRO D CG    1 
ATOM   5916 C CD    . PRO B 2 342 ? 132.085 145.323 87.549  1.00 321.51 ? 342 PRO D CD    1 
ATOM   5917 N N     . THR B 2 343 ? 131.899 141.371 86.224  1.00 98.76  ? 343 THR D N     1 
ATOM   5918 C CA    . THR B 2 343 ? 132.689 140.162 86.329  1.00 98.76  ? 343 THR D CA    1 
ATOM   5919 C C     . THR B 2 343 ? 132.370 139.145 85.249  1.00 98.76  ? 343 THR D C     1 
ATOM   5920 O O     . THR B 2 343 ? 131.632 139.402 84.300  1.00 98.76  ? 343 THR D O     1 
ATOM   5921 C CB    . THR B 2 343 ? 132.534 139.523 87.705  1.00 138.25 ? 343 THR D CB    1 
ATOM   5922 O OG1   . THR B 2 343 ? 133.478 138.451 87.830  1.00 138.25 ? 343 THR D OG1   1 
ATOM   5923 C CG2   . THR B 2 343 ? 131.147 138.986 87.902  1.00 138.25 ? 343 THR D CG2   1 
ATOM   5924 N N     . ALA B 2 344 ? 132.986 137.978 85.389  1.00 91.23  ? 344 ALA D N     1 
ATOM   5925 C CA    . ALA B 2 344 ? 132.902 136.900 84.423  1.00 91.23  ? 344 ALA D CA    1 
ATOM   5926 C C     . ALA B 2 344 ? 133.001 135.588 85.159  1.00 91.23  ? 344 ALA D C     1 
ATOM   5927 O O     . ALA B 2 344 ? 133.417 135.552 86.315  1.00 91.23  ? 344 ALA D O     1 
ATOM   5928 C CB    . ALA B 2 344 ? 134.019 136.999 83.399  1.00 124.40 ? 344 ALA D CB    1 
ATOM   5929 N N     . ILE B 2 345 ? 132.602 134.511 84.514  1.00 87.73  ? 345 ILE D N     1 
ATOM   5930 C CA    . ILE B 2 345 ? 132.669 133.237 85.195  1.00 87.73  ? 345 ILE D CA    1 
ATOM   5931 C C     . ILE B 2 345 ? 134.076 132.745 85.115  1.00 87.73  ? 345 ILE D C     1 
ATOM   5932 O O     . ILE B 2 345 ? 134.631 132.675 84.023  1.00 87.73  ? 345 ILE D O     1 
ATOM   5933 C CB    . ILE B 2 345 ? 131.761 132.222 84.554  1.00 129.81 ? 345 ILE D CB    1 
ATOM   5934 C CG1   . ILE B 2 345 ? 130.388 132.754 84.553  1.00 129.81 ? 345 ILE D CG1   1 
ATOM   5935 C CG2   . ILE B 2 345 ? 131.823 130.964 85.396  1.00 129.81 ? 345 ILE D CG2   1 
ATOM   5936 C CD1   . ILE B 2 345 ? 129.440 131.987 83.725  1.00 129.81 ? 345 ILE D CD1   1 
ATOM   5937 N N     . LYS B 2 346 ? 134.664 132.412 86.229  1.00 89.12  ? 346 LYS D N     1 
ATOM   5938 C CA    . LYS B 2 346 ? 136.012 131.883 86.209  1.00 89.12  ? 346 LYS D CA    1 
ATOM   5939 C C     . LYS B 2 346 ? 135.934 130.377 86.231  1.00 89.12  ? 346 LYS D C     1 
ATOM   5940 O O     . LYS B 2 346 ? 135.138 129.820 86.977  1.00 89.12  ? 346 LYS D O     1 
ATOM   5941 C CB    . LYS B 2 346 ? 136.804 132.387 87.392  1.00 133.56 ? 346 LYS D CB    1 
ATOM   5942 C CG    . LYS B 2 346 ? 137.031 133.857 87.359  1.00 133.56 ? 346 LYS D CG    1 
ATOM   5943 C CD    . LYS B 2 346 ? 137.849 134.357 88.509  1.00 133.56 ? 346 LYS D CD    1 
ATOM   5944 C CE    . LYS B 2 346 ? 138.062 135.836 88.397  1.00 133.56 ? 346 LYS D CE    1 
ATOM   5945 N NZ    . LYS B 2 346 ? 138.908 136.394 89.473  1.00 133.56 ? 346 LYS D NZ    1 
ATOM   5946 N N     . ALA B 2 347 ? 136.715 129.709 85.402  1.00 89.84  ? 347 ALA D N     1 
ATOM   5947 C CA    . ALA B 2 347 ? 136.669 128.264 85.388  1.00 89.84  ? 347 ALA D CA    1 
ATOM   5948 C C     . ALA B 2 347 ? 138.017 127.694 85.019  1.00 89.84  ? 347 ALA D C     1 
ATOM   5949 O O     . ALA B 2 347 ? 138.655 128.170 84.085  1.00 89.84  ? 347 ALA D O     1 
ATOM   5950 C CB    . ALA B 2 347 ? 135.640 127.761 84.401  1.00 122.51 ? 347 ALA D CB    1 
ATOM   5951 N N     . ASP B 2 348 ? 138.450 126.689 85.758  1.00 92.49  ? 348 ASP D N     1 
ATOM   5952 C CA    . ASP B 2 348 ? 139.713 126.012 85.498  1.00 92.49  ? 348 ASP D CA    1 
ATOM   5953 C C     . ASP B 2 348 ? 139.718 124.716 86.282  1.00 92.49  ? 348 ASP D C     1 
ATOM   5954 O O     . ASP B 2 348 ? 138.748 124.425 86.984  1.00 92.49  ? 348 ASP D O     1 
ATOM   5955 C CB    . ASP B 2 348 ? 140.877 126.895 85.863  1.00 118.91 ? 348 ASP D CB    1 
ATOM   5956 C CG    . ASP B 2 348 ? 142.117 126.580 85.088  1.00 118.91 ? 348 ASP D CG    1 
ATOM   5957 O OD1   . ASP B 2 348 ? 142.244 125.466 84.587  1.00 118.91 ? 348 ASP D OD1   1 
ATOM   5958 O OD2   . ASP B 2 348 ? 142.985 127.451 84.988  1.00 118.91 ? 348 ASP D OD2   1 
ATOM   5959 N N     . SER B 2 349 ? 140.806 123.939 86.196  1.00 96.66  ? 349 SER D N     1 
ATOM   5960 C CA    . SER B 2 349 ? 140.854 122.676 86.940  1.00 96.66  ? 349 SER D CA    1 
ATOM   5961 C C     . SER B 2 349 ? 142.174 122.313 87.604  1.00 96.66  ? 349 SER D C     1 
ATOM   5962 O O     . SER B 2 349 ? 143.254 122.747 87.216  1.00 96.66  ? 349 SER D O     1 
ATOM   5963 C CB    . SER B 2 349 ? 140.505 121.508 86.063  1.00 130.19 ? 349 SER D CB    1 
ATOM   5964 O OG    . SER B 2 349 ? 141.485 121.329 85.092  1.00 130.19 ? 349 SER D OG    1 
ATOM   5965 N N     . THR B 2 350 ? 142.050 121.456 88.606  1.00 99.50  ? 350 THR D N     1 
ATOM   5966 C CA    . THR B 2 350 ? 143.130 120.845 89.363  1.00 99.50  ? 350 THR D CA    1 
ATOM   5967 C C     . THR B 2 350 ? 143.068 119.341 89.165  1.00 99.50  ? 350 THR D C     1 
ATOM   5968 O O     . THR B 2 350 ? 142.156 118.833 88.513  1.00 99.50  ? 350 THR D O     1 
ATOM   5969 C CB    . THR B 2 350 ? 143.020 121.150 90.844  1.00 139.28 ? 350 THR D CB    1 
ATOM   5970 O OG1   . THR B 2 350 ? 141.898 120.471 91.380  1.00 139.28 ? 350 THR D OG1   1 
ATOM   5971 C CG2   . THR B 2 350 ? 142.820 122.594 91.032  1.00 139.28 ? 350 THR D CG2   1 
ATOM   5972 N N     . THR B 2 351 ? 144.041 118.619 89.700  1.00 95.80  ? 351 THR D N     1 
ATOM   5973 C CA    . THR B 2 351 ? 144.068 117.189 89.491  1.00 95.80  ? 351 THR D CA    1 
ATOM   5974 C C     . THR B 2 351 ? 143.212 116.430 90.482  1.00 95.80  ? 351 THR D C     1 
ATOM   5975 O O     . THR B 2 351 ? 142.806 116.957 91.511  1.00 95.80  ? 351 THR D O     1 
ATOM   5976 C CB    . THR B 2 351 ? 145.472 116.681 89.589  1.00 134.10 ? 351 THR D CB    1 
ATOM   5977 O OG1   . THR B 2 351 ? 145.977 116.974 90.889  1.00 134.10 ? 351 THR D OG1   1 
ATOM   5978 C CG2   . THR B 2 351 ? 146.331 117.368 88.560  1.00 134.10 ? 351 THR D CG2   1 
ATOM   5979 N N     . LEU B 2 352 ? 142.956 115.163 90.136  1.00 92.84  ? 352 LEU D N     1 
ATOM   5980 C CA    . LEU B 2 352 ? 142.267 114.165 90.944  1.00 92.84  ? 352 LEU D CA    1 
ATOM   5981 C C     . LEU B 2 352 ? 143.246 113.111 91.354  1.00 92.84  ? 352 LEU D C     1 
ATOM   5982 O O     . LEU B 2 352 ? 144.102 112.719 90.561  1.00 92.84  ? 352 LEU D O     1 
ATOM   5983 C CB    . LEU B 2 352 ? 141.182 113.414 90.181  1.00 137.37 ? 352 LEU D CB    1 
ATOM   5984 C CG    . LEU B 2 352 ? 139.930 114.141 89.811  1.00 137.37 ? 352 LEU D CG    1 
ATOM   5985 C CD1   . LEU B 2 352 ? 139.113 113.300 88.875  1.00 137.37 ? 352 LEU D CD1   1 
ATOM   5986 C CD2   . LEU B 2 352 ? 139.133 114.378 91.087  1.00 137.37 ? 352 LEU D CD2   1 
ATOM   5987 N N     . THR B 2 353 ? 143.081 112.608 92.549  1.00 95.83  ? 353 THR D N     1 
ATOM   5988 C CA    . THR B 2 353 ? 143.820 111.438 92.952  1.00 95.83  ? 353 THR D CA    1 
ATOM   5989 C C     . THR B 2 353 ? 142.829 110.323 93.172  1.00 95.83  ? 353 THR D C     1 
ATOM   5990 O O     . THR B 2 353 ? 143.195 109.225 93.613  1.00 95.83  ? 353 THR D O     1 
ATOM   5991 C CB    . THR B 2 353 ? 144.654 111.718 94.197  1.00 134.14 ? 353 THR D CB    1 
ATOM   5992 O OG1   . THR B 2 353 ? 143.794 112.001 95.289  1.00 134.14 ? 353 THR D OG1   1 
ATOM   5993 C CG2   . THR B 2 353 ? 145.544 112.924 93.975  1.00 134.14 ? 353 THR D CG2   1 
ATOM   5994 N N     . ASP B 2 354 ? 141.581 110.611 92.848  1.00 98.52  ? 354 ASP D N     1 
ATOM   5995 C CA    . ASP B 2 354 ? 140.454 109.709 92.958  1.00 98.52  ? 354 ASP D CA    1 
ATOM   5996 C C     . ASP B 2 354 ? 140.361 108.914 91.672  1.00 98.52  ? 354 ASP D C     1 
ATOM   5997 O O     . ASP B 2 354 ? 140.080 109.465 90.608  1.00 98.52  ? 354 ASP D O     1 
ATOM   5998 C CB    . ASP B 2 354 ? 139.191 110.520 93.216  1.00 126.67 ? 354 ASP D CB    1 
ATOM   5999 C CG    . ASP B 2 354 ? 137.950 109.662 93.432  1.00 126.67 ? 354 ASP D CG    1 
ATOM   6000 O OD1   . ASP B 2 354 ? 137.880 108.535 92.920  1.00 126.67 ? 354 ASP D OD1   1 
ATOM   6001 O OD2   . ASP B 2 354 ? 137.032 110.135 94.122  1.00 126.67 ? 354 ASP D OD2   1 
ATOM   6002 N N     . GLU B 2 355 ? 140.592 107.619 91.766  1.00 96.25  ? 355 GLU D N     1 
ATOM   6003 C CA    . GLU B 2 355 ? 140.664 106.752 90.607  1.00 96.25  ? 355 GLU D CA    1 
ATOM   6004 C C     . GLU B 2 355 ? 139.310 106.358 90.037  1.00 96.25  ? 355 GLU D C     1 
ATOM   6005 O O     . GLU B 2 355 ? 139.262 105.701 88.997  1.00 96.25  ? 355 GLU D O     1 
ATOM   6006 C CB    . GLU B 2 355 ? 141.444 105.490 90.967  1.00 129.28 ? 355 GLU D CB    1 
ATOM   6007 C CG    . GLU B 2 355 ? 140.710 104.496 91.875  1.00 129.28 ? 355 GLU D CG    1 
ATOM   6008 C CD    . GLU B 2 355 ? 140.838 104.796 93.345  1.00 129.28 ? 355 GLU D CD    1 
ATOM   6009 O OE1   . GLU B 2 355 ? 141.125 105.938 93.701  1.00 129.28 ? 355 GLU D OE1   1 
ATOM   6010 O OE2   . GLU B 2 355 ? 140.645 103.880 94.148  1.00 129.28 ? 355 GLU D OE2   1 
ATOM   6011 N N     . LYS B 2 356 ? 138.218 106.680 90.697  1.00 91.91  ? 356 LYS D N     1 
ATOM   6012 C CA    . LYS B 2 356 ? 136.936 106.192 90.226  1.00 91.91  ? 356 LYS D CA    1 
ATOM   6013 C C     . LYS B 2 356 ? 136.252 107.128 89.252  1.00 91.91  ? 356 LYS D C     1 
ATOM   6014 O O     . LYS B 2 356 ? 135.433 106.678 88.450  1.00 91.91  ? 356 LYS D O     1 
ATOM   6015 C CB    . LYS B 2 356 ? 136.008 105.940 91.405  1.00 137.74 ? 356 LYS D CB    1 
ATOM   6016 C CG    . LYS B 2 356 ? 136.500 104.908 92.403  1.00 137.74 ? 356 LYS D CG    1 
ATOM   6017 C CD    . LYS B 2 356 ? 136.638 103.530 91.811  1.00 137.74 ? 356 LYS D CD    1 
ATOM   6018 C CE    . LYS B 2 356 ? 137.033 102.519 92.874  1.00 137.74 ? 356 LYS D CE    1 
ATOM   6019 N NZ    . LYS B 2 356 ? 137.210 101.145 92.317  1.00 137.74 ? 356 LYS D NZ    1 
ATOM   6020 N N     . LEU B 2 357 ? 136.530 108.413 89.292  1.00 90.29  ? 357 LEU D N     1 
ATOM   6021 C CA    . LEU B 2 357 ? 135.835 109.348 88.432  1.00 90.29  ? 357 LEU D CA    1 
ATOM   6022 C C     . LEU B 2 357 ? 136.805 109.978 87.460  1.00 90.29  ? 357 LEU D C     1 
ATOM   6023 O O     . LEU B 2 357 ? 137.816 110.538 87.869  1.00 90.29  ? 357 LEU D O     1 
ATOM   6024 C CB    . LEU B 2 357 ? 135.203 110.435 89.256  1.00 133.60 ? 357 LEU D CB    1 
ATOM   6025 C CG    . LEU B 2 357 ? 134.221 109.988 90.306  1.00 133.60 ? 357 LEU D CG    1 
ATOM   6026 C CD1   . LEU B 2 357 ? 133.817 111.196 91.107  1.00 133.60 ? 357 LEU D CD1   1 
ATOM   6027 C CD2   . LEU B 2 357 ? 132.978 109.344 89.652  1.00 133.60 ? 357 LEU D CD2   1 
ATOM   6028 N N     . ALA B 2 358 ? 136.500 109.922 86.186  1.00 92.42  ? 358 ALA D N     1 
ATOM   6029 C CA    . ALA B 2 358 ? 137.407 110.528 85.245  1.00 92.42  ? 358 ALA D CA    1 
ATOM   6030 C C     . ALA B 2 358 ? 137.527 112.008 85.504  1.00 92.42  ? 358 ALA D C     1 
ATOM   6031 O O     . ALA B 2 358 ? 138.589 112.603 85.316  1.00 92.42  ? 358 ALA D O     1 
ATOM   6032 C CB    . ALA B 2 358 ? 136.912 110.293 83.827  1.00 126.03 ? 358 ALA D CB    1 
ATOM   6033 N N     . ARG B 2 359 ? 136.428 112.626 85.888  1.00 91.53  ? 359 ARG D N     1 
ATOM   6034 C CA    . ARG B 2 359 ? 136.383 114.039 86.153  1.00 91.53  ? 359 ARG D CA    1 
ATOM   6035 C C     . ARG B 2 359 ? 135.224 114.309 87.074  1.00 91.53  ? 359 ARG D C     1 
ATOM   6036 O O     . ARG B 2 359 ? 134.289 113.526 87.151  1.00 91.53  ? 359 ARG D O     1 
ATOM   6037 C CB    . ARG B 2 359 ? 136.236 114.815 84.871  1.00 134.38 ? 359 ARG D CB    1 
ATOM   6038 C CG    . ARG B 2 359 ? 135.048 114.435 84.039  1.00 134.38 ? 359 ARG D CG    1 
ATOM   6039 C CD    . ARG B 2 359 ? 135.035 115.192 82.766  1.00 134.38 ? 359 ARG D CD    1 
ATOM   6040 N NE    . ARG B 2 359 ? 136.277 114.997 82.043  1.00 134.38 ? 359 ARG D NE    1 
ATOM   6041 C CZ    . ARG B 2 359 ? 136.567 114.008 81.215  1.00 134.38 ? 359 ARG D CZ    1 
ATOM   6042 N NH1   . ARG B 2 359 ? 135.709 113.050 80.929  1.00 134.38 ? 359 ARG D NH1   1 
ATOM   6043 N NH2   . ARG B 2 359 ? 137.765 113.990 80.655  1.00 134.38 ? 359 ARG D NH2   1 
ATOM   6044 N N     . SER B 2 360 ? 135.294 115.427 87.755  1.00 89.84  ? 360 SER D N     1 
ATOM   6045 C CA    . SER B 2 360 ? 134.266 115.856 88.683  1.00 89.84  ? 360 SER D CA    1 
ATOM   6046 C C     . SER B 2 360 ? 134.449 117.327 88.918  1.00 89.84  ? 360 SER D C     1 
ATOM   6047 O O     . SER B 2 360 ? 135.424 117.903 88.452  1.00 89.84  ? 360 SER D O     1 
ATOM   6048 C CB    . SER B 2 360 ? 134.389 115.135 89.996  1.00 121.01 ? 360 SER D CB    1 
ATOM   6049 O OG    . SER B 2 360 ? 135.577 115.523 90.647  1.00 121.01 ? 360 SER D OG    1 
ATOM   6050 N N     . GLY B 2 361 ? 133.547 117.941 89.660  1.00 89.76  ? 361 GLY D N     1 
ATOM   6051 C CA    . GLY B 2 361 ? 133.781 119.338 89.989  1.00 89.76  ? 361 GLY D CA    1 
ATOM   6052 C C     . GLY B 2 361 ? 132.700 119.974 90.838  1.00 89.76  ? 361 GLY D C     1 
ATOM   6053 O O     . GLY B 2 361 ? 131.677 119.362 91.139  1.00 89.76  ? 361 GLY D O     1 
ATOM   6054 N N     . ILE B 2 362 ? 132.977 121.211 91.265  1.00 87.58  ? 362 ILE D N     1 
ATOM   6055 C CA    . ILE B 2 362 ? 132.053 121.996 92.068  1.00 87.58  ? 362 ILE D CA    1 
ATOM   6056 C C     . ILE B 2 362 ? 131.963 123.421 91.616  1.00 87.58  ? 362 ILE D C     1 
ATOM   6057 O O     . ILE B 2 362 ? 132.843 123.939 90.938  1.00 87.58  ? 362 ILE D O     1 
ATOM   6058 C CB    . ILE B 2 362 ? 132.416 122.060 93.514  1.00 129.59 ? 362 ILE D CB    1 
ATOM   6059 C CG1   . ILE B 2 362 ? 133.734 122.721 93.641  1.00 129.59 ? 362 ILE D CG1   1 
ATOM   6060 C CG2   . ILE B 2 362 ? 132.390 120.710 94.049  1.00 129.59 ? 362 ILE D CG2   1 
ATOM   6061 C CD1   . ILE B 2 362 ? 134.050 123.101 95.010  1.00 129.59 ? 362 ILE D CD1   1 
ATOM   6062 N N     . THR B 2 363 ? 130.929 124.088 92.064  1.00 89.12  ? 363 THR D N     1 
ATOM   6063 C CA    . THR B 2 363 ? 130.884 125.513 91.846  1.00 89.12  ? 363 THR D CA    1 
ATOM   6064 C C     . THR B 2 363 ? 130.625 126.235 93.130  1.00 89.12  ? 363 THR D C     1 
ATOM   6065 O O     . THR B 2 363 ? 129.949 125.731 94.029  1.00 89.12  ? 363 THR D O     1 
ATOM   6066 C CB    . THR B 2 363 ? 129.819 125.956 90.874  1.00 124.75 ? 363 THR D CB    1 
ATOM   6067 O OG1   . THR B 2 363 ? 128.524 125.741 91.423  1.00 124.75 ? 363 THR D OG1   1 
ATOM   6068 C CG2   . THR B 2 363 ? 129.928 125.182 89.620  1.00 124.75 ? 363 THR D CG2   1 
ATOM   6069 N N     . LEU B 2 364 ? 131.138 127.437 93.180  1.00 85.91  ? 364 LEU D N     1 
ATOM   6070 C CA    . LEU B 2 364 ? 130.867 128.341 94.251  1.00 85.91  ? 364 LEU D CA    1 
ATOM   6071 C C     . LEU B 2 364 ? 130.147 129.534 93.666  1.00 85.91  ? 364 LEU D C     1 
ATOM   6072 O O     . LEU B 2 364 ? 130.671 130.208 92.789  1.00 85.91  ? 364 LEU D O     1 
ATOM   6073 C CB    . LEU B 2 364 ? 132.165 128.738 94.919  1.00 127.11 ? 364 LEU D CB    1 
ATOM   6074 C CG    . LEU B 2 364 ? 133.078 127.598 95.369  1.00 127.11 ? 364 LEU D CG    1 
ATOM   6075 C CD1   . LEU B 2 364 ? 134.354 128.177 95.918  1.00 127.11 ? 364 LEU D CD1   1 
ATOM   6076 C CD2   . LEU B 2 364 ? 132.430 126.762 96.407  1.00 127.11 ? 364 LEU D CD2   1 
ATOM   6077 N N     . MET B 2 365 ? 128.986 129.838 94.175  1.00 88.04  ? 365 MET D N     1 
ATOM   6078 C CA    . MET B 2 365 ? 128.186 130.902 93.627  1.00 88.04  ? 365 MET D CA    1 
ATOM   6079 C C     . MET B 2 365 ? 127.854 131.960 94.658  1.00 88.04  ? 365 MET D C     1 
ATOM   6080 O O     . MET B 2 365 ? 127.358 131.649 95.740  1.00 88.04  ? 365 MET D O     1 
ATOM   6081 C CB    . MET B 2 365 ? 126.907 130.329 93.136  1.00 126.44 ? 365 MET D CB    1 
ATOM   6082 C CG    . MET B 2 365 ? 127.070 129.300 92.116  1.00 126.44 ? 365 MET D CG    1 
ATOM   6083 S SD    . MET B 2 365 ? 125.502 128.592 91.629  1.00 126.44 ? 365 MET D SD    1 
ATOM   6084 C CE    . MET B 2 365 ? 125.169 127.432 92.946  1.00 126.44 ? 365 MET D CE    1 
ATOM   6085 N N     . ASN B 2 366 ? 128.048 133.204 94.313  1.00 85.83  ? 366 ASN D N     1 
ATOM   6086 C CA    . ASN B 2 366 ? 127.577 134.278 95.151  1.00 85.83  ? 366 ASN D CA    1 
ATOM   6087 C C     . ASN B 2 366 ? 126.374 134.777 94.407  1.00 85.83  ? 366 ASN D C     1 
ATOM   6088 O O     . ASN B 2 366 ? 126.500 135.431 93.366  1.00 85.83  ? 366 ASN D O     1 
ATOM   6089 C CB    . ASN B 2 366 ? 128.618 135.336 95.379  1.00 116.28 ? 366 ASN D CB    1 
ATOM   6090 C CG    . ASN B 2 366 ? 128.195 136.283 96.396  1.00 116.28 ? 366 ASN D CG    1 
ATOM   6091 O OD1   . ASN B 2 366 ? 127.010 136.474 96.588  1.00 116.28 ? 366 ASN D OD1   1 
ATOM   6092 N ND2   . ASN B 2 366 ? 129.140 136.875 97.101  1.00 116.28 ? 366 ASN D ND2   1 
ATOM   6093 N N     . HIS B 2 367 ? 125.215 134.352 94.869  1.00 86.69  ? 367 HIS D N     1 
ATOM   6094 C CA    . HIS B 2 367 ? 123.993 134.514 94.115  1.00 86.69  ? 367 HIS D CA    1 
ATOM   6095 C C     . HIS B 2 367 ? 122.876 134.954 95.023  1.00 86.69  ? 367 HIS D C     1 
ATOM   6096 O O     . HIS B 2 367 ? 122.766 134.483 96.152  1.00 86.69  ? 367 HIS D O     1 
ATOM   6097 C CB    . HIS B 2 367 ? 123.649 133.228 93.435  1.00 117.88 ? 367 HIS D CB    1 
ATOM   6098 C CG    . HIS B 2 367 ? 122.422 133.276 92.627  1.00 117.88 ? 367 HIS D CG    1 
ATOM   6099 N ND1   . HIS B 2 367 ? 121.194 133.205 93.192  1.00 117.88 ? 367 HIS D ND1   1 
ATOM   6100 C CD2   . HIS B 2 367 ? 122.223 133.337 91.304  1.00 117.88 ? 367 HIS D CD2   1 
ATOM   6101 C CE1   . HIS B 2 367 ? 120.275 133.233 92.255  1.00 117.88 ? 367 HIS D CE1   1 
ATOM   6102 N NE2   . HIS B 2 367 ? 120.874 133.315 91.095  1.00 117.88 ? 367 HIS D NE2   1 
ATOM   6103 N N     . SER B 2 368 ? 122.024 135.826 94.501  1.00 85.37  ? 368 SER D N     1 
ATOM   6104 C CA    . SER B 2 368 ? 120.958 136.467 95.248  1.00 85.37  ? 368 SER D CA    1 
ATOM   6105 C C     . SER B 2 368 ? 119.929 135.507 95.786  1.00 85.37  ? 368 SER D C     1 
ATOM   6106 O O     . SER B 2 368 ? 119.201 135.851 96.711  1.00 85.37  ? 368 SER D O     1 
ATOM   6107 C CB    . SER B 2 368 ? 120.258 137.475 94.378  1.00 114.99 ? 368 SER D CB    1 
ATOM   6108 O OG    . SER B 2 368 ? 119.608 136.844 93.300  1.00 114.99 ? 368 SER D OG    1 
ATOM   6109 N N     . GLY B 2 369 ? 119.870 134.307 95.260  1.00 81.71  ? 369 GLY D N     1 
ATOM   6110 C CA    . GLY B 2 369 ? 118.925 133.324 95.706  1.00 81.71  ? 369 GLY D CA    1 
ATOM   6111 C C     . GLY B 2 369 ? 119.134 132.903 97.128  1.00 81.71  ? 369 GLY D C     1 
ATOM   6112 O O     . GLY B 2 369 ? 118.238 132.300 97.714  1.00 81.71  ? 369 GLY D O     1 
ATOM   6113 N N     . VAL B 2 370 ? 120.269 133.223 97.716  1.00 80.07  ? 370 VAL D N     1 
ATOM   6114 C CA    . VAL B 2 370 ? 120.446 132.875 99.102  1.00 80.07  ? 370 VAL D CA    1 
ATOM   6115 C C     . VAL B 2 370 ? 119.395 133.594 99.902  1.00 80.07  ? 370 VAL D C     1 
ATOM   6116 O O     . VAL B 2 370 ? 118.960 133.116 100.955 1.00 80.07  ? 370 VAL D O     1 
ATOM   6117 C CB    . VAL B 2 370 ? 121.848 133.214 99.606  1.00 116.43 ? 370 VAL D CB    1 
ATOM   6118 C CG1   . VAL B 2 370 ? 122.050 134.694 99.706  1.00 116.43 ? 370 VAL D CG1   1 
ATOM   6119 C CG2   . VAL B 2 370 ? 122.055 132.594 100.946 1.00 116.43 ? 370 VAL D CG2   1 
ATOM   6120 N N     . ALA B 2 371 ? 118.925 134.715 99.381  1.00 81.56  ? 371 ALA D N     1 
ATOM   6121 C CA    . ALA B 2 371 ? 117.919 135.522 100.033 1.00 81.56  ? 371 ALA D CA    1 
ATOM   6122 C C     . ALA B 2 371 ? 116.650 134.761 100.241 1.00 81.56  ? 371 ALA D C     1 
ATOM   6123 O O     . ALA B 2 371 ? 115.890 135.090 101.144 1.00 81.56  ? 371 ALA D O     1 
ATOM   6124 C CB    . ALA B 2 371 ? 117.639 136.754 99.185  1.00 111.22 ? 371 ALA D CB    1 
ATOM   6125 N N     . ASN B 2 372 ? 116.366 133.787 99.405  1.00 76.48  ? 372 ASN D N     1 
ATOM   6126 C CA    . ASN B 2 372 ? 115.151 133.030 99.571  1.00 76.48  ? 372 ASN D CA    1 
ATOM   6127 C C     . ASN B 2 372 ? 115.256 132.009 100.673 1.00 76.48  ? 372 ASN D C     1 
ATOM   6128 O O     . ASN B 2 372 ? 114.247 131.678 101.293 1.00 76.48  ? 372 ASN D O     1 
ATOM   6129 C CB    . ASN B 2 372 ? 114.786 132.374 98.276  1.00 103.61 ? 372 ASN D CB    1 
ATOM   6130 C CG    . ASN B 2 372 ? 114.344 133.368 97.258  1.00 103.61 ? 372 ASN D CG    1 
ATOM   6131 O OD1   . ASN B 2 372 ? 113.801 134.415 97.584  1.00 103.61 ? 372 ASN D OD1   1 
ATOM   6132 N ND2   . ASN B 2 372 ? 114.570 133.057 96.011  1.00 103.61 ? 372 ASN D ND2   1 
ATOM   6133 N N     . LEU B 2 373 ? 116.440 131.494 100.933 1.00 79.44  ? 373 LEU D N     1 
ATOM   6134 C CA    . LEU B 2 373 ? 116.619 130.615 102.072 1.00 79.44  ? 373 LEU D CA    1 
ATOM   6135 C C     . LEU B 2 373 ? 116.441 131.435 103.330 1.00 79.44  ? 373 LEU D C     1 
ATOM   6136 O O     . LEU B 2 373 ? 115.713 131.047 104.262 1.00 79.44  ? 373 LEU D O     1 
ATOM   6137 C CB    . LEU B 2 373 ? 117.999 129.950 102.012 1.00 117.54 ? 373 LEU D CB    1 
ATOM   6138 C CG    . LEU B 2 373 ? 118.409 128.903 103.053 1.00 117.54 ? 373 LEU D CG    1 
ATOM   6139 C CD1   . LEU B 2 373 ? 119.359 127.894 102.447 1.00 117.54 ? 373 LEU D CD1   1 
ATOM   6140 C CD2   . LEU B 2 373 ? 119.116 129.587 104.259 1.00 117.54 ? 373 LEU D CD2   1 
ATOM   6141 N N     . PHE B 2 374 ? 117.044 132.612 103.333 1.00 80.18  ? 374 PHE D N     1 
ATOM   6142 C CA    . PHE B 2 374 ? 116.943 133.491 104.458 1.00 80.18  ? 374 PHE D CA    1 
ATOM   6143 C C     . PHE B 2 374 ? 115.521 133.933 104.664 1.00 80.18  ? 374 PHE D C     1 
ATOM   6144 O O     . PHE B 2 374 ? 115.064 133.978 105.799 1.00 80.18  ? 374 PHE D O     1 
ATOM   6145 C CB    . PHE B 2 374 ? 117.785 134.709 104.257 1.00 111.84 ? 374 PHE D CB    1 
ATOM   6146 C CG    . PHE B 2 374 ? 119.222 134.491 104.239 1.00 111.84 ? 374 PHE D CG    1 
ATOM   6147 C CD1   . PHE B 2 374 ? 119.808 133.413 104.802 1.00 111.84 ? 374 PHE D CD1   1 
ATOM   6148 C CD2   . PHE B 2 374 ? 120.013 135.446 103.676 1.00 111.84 ? 374 PHE D CD2   1 
ATOM   6149 C CE1   . PHE B 2 374 ? 121.155 133.281 104.773 1.00 111.84 ? 374 PHE D CE1   1 
ATOM   6150 C CE2   . PHE B 2 374 ? 121.353 135.315 103.646 1.00 111.84 ? 374 PHE D CE2   1 
ATOM   6151 C CZ    . PHE B 2 374 ? 121.926 134.230 104.193 1.00 111.84 ? 374 PHE D CZ    1 
ATOM   6152 N N     . GLN B 2 375 ? 114.808 134.296 103.607 1.00 76.61  ? 375 GLN D N     1 
ATOM   6153 C CA    . GLN B 2 375 ? 113.454 134.787 103.804 1.00 76.61  ? 375 GLN D CA    1 
ATOM   6154 C C     . GLN B 2 375 ? 112.560 133.705 104.309 1.00 76.61  ? 375 GLN D C     1 
ATOM   6155 O O     . GLN B 2 375 ? 111.691 133.964 105.128 1.00 76.61  ? 375 GLN D O     1 
ATOM   6156 C CB    . GLN B 2 375 ? 112.848 135.348 102.539 1.00 107.02 ? 375 GLN D CB    1 
ATOM   6157 C CG    . GLN B 2 375 ? 111.504 135.923 102.729 1.00 107.02 ? 375 GLN D CG    1 
ATOM   6158 C CD    . GLN B 2 375 ? 111.496 137.091 103.671 1.00 107.02 ? 375 GLN D CD    1 
ATOM   6159 O OE1   . GLN B 2 375 ? 112.209 138.062 103.462 1.00 107.02 ? 375 GLN D OE1   1 
ATOM   6160 N NE2   . GLN B 2 375 ? 110.670 137.023 104.717 1.00 107.02 ? 375 GLN D NE2   1 
ATOM   6161 N N     . PHE B 2 376 ? 112.742 132.488 103.860 1.00 74.00  ? 376 PHE D N     1 
ATOM   6162 C CA    . PHE B 2 376 ? 111.924 131.411 104.382 1.00 74.00  ? 376 PHE D CA    1 
ATOM   6163 C C     . PHE B 2 376 ? 112.079 131.314 105.876 1.00 74.00  ? 376 PHE D C     1 
ATOM   6164 O O     . PHE B 2 376 ? 111.094 131.308 106.625 1.00 74.00  ? 376 PHE D O     1 
ATOM   6165 C CB    . PHE B 2 376 ? 112.360 130.126 103.746 1.00 103.22 ? 376 PHE D CB    1 
ATOM   6166 C CG    . PHE B 2 376 ? 111.666 128.971 104.230 1.00 103.22 ? 376 PHE D CG    1 
ATOM   6167 C CD1   . PHE B 2 376 ? 110.464 128.637 103.707 1.00 103.22 ? 376 PHE D CD1   1 
ATOM   6168 C CD2   . PHE B 2 376 ? 112.215 128.180 105.190 1.00 103.22 ? 376 PHE D CD2   1 
ATOM   6169 C CE1   . PHE B 2 376 ? 109.813 127.542 104.119 1.00 103.22 ? 376 PHE D CE1   1 
ATOM   6170 C CE2   . PHE B 2 376 ? 111.563 127.078 105.619 1.00 103.22 ? 376 PHE D CE2   1 
ATOM   6171 C CZ    . PHE B 2 376 ? 110.352 126.760 105.077 1.00 103.22 ? 376 PHE D CZ    1 
ATOM   6172 N N     . LEU B 2 377 ? 113.318 131.300 106.336 1.00 74.97  ? 377 LEU D N     1 
ATOM   6173 C CA    . LEU B 2 377 ? 113.564 131.193 107.758 1.00 74.97  ? 377 LEU D CA    1 
ATOM   6174 C C     . LEU B 2 377 ? 113.100 132.422 108.501 1.00 74.97  ? 377 LEU D C     1 
ATOM   6175 O O     . LEU B 2 377 ? 112.594 132.316 109.617 1.00 74.97  ? 377 LEU D O     1 
ATOM   6176 C CB    . LEU B 2 377 ? 115.030 130.962 108.007 1.00 110.93 ? 377 LEU D CB    1 
ATOM   6177 C CG    . LEU B 2 377 ? 115.616 129.641 107.595 1.00 110.93 ? 377 LEU D CG    1 
ATOM   6178 C CD1   . LEU B 2 377 ? 117.115 129.734 107.660 1.00 110.93 ? 377 LEU D CD1   1 
ATOM   6179 C CD2   . LEU B 2 377 ? 115.113 128.529 108.476 1.00 110.93 ? 377 LEU D CD2   1 
ATOM   6180 N N     . LEU B 2 378 ? 113.255 133.585 107.917 1.00 73.10  ? 378 LEU D N     1 
ATOM   6181 C CA    . LEU B 2 378 ? 112.847 134.798 108.588 1.00 73.10  ? 378 LEU D CA    1 
ATOM   6182 C C     . LEU B 2 378 ? 111.352 134.849 108.729 1.00 73.10  ? 378 LEU D C     1 
ATOM   6183 O O     . LEU B 2 378 ? 110.858 135.285 109.763 1.00 73.10  ? 378 LEU D O     1 
ATOM   6184 C CB    . LEU B 2 378 ? 113.298 136.017 107.821 1.00 108.16 ? 378 LEU D CB    1 
ATOM   6185 C CG    . LEU B 2 378 ? 112.965 137.359 108.405 1.00 108.16 ? 378 LEU D CG    1 
ATOM   6186 C CD1   . LEU B 2 378 ? 113.586 137.500 109.768 1.00 108.16 ? 378 LEU D CD1   1 
ATOM   6187 C CD2   . LEU B 2 378 ? 113.498 138.394 107.527 1.00 108.16 ? 378 LEU D CD2   1 
ATOM   6188 N N     . THR B 2 379 ? 110.606 134.416 107.708 1.00 68.67  ? 379 THR D N     1 
ATOM   6189 C CA    . THR B 2 379 ? 109.150 134.393 107.820 1.00 68.67  ? 379 THR D CA    1 
ATOM   6190 C C     . THR B 2 379 ? 108.731 133.496 108.944 1.00 68.67  ? 379 THR D C     1 
ATOM   6191 O O     . THR B 2 379 ? 107.870 133.863 109.756 1.00 68.67  ? 379 THR D O     1 
ATOM   6192 C CB    . THR B 2 379 ? 108.456 133.923 106.550 1.00 96.12  ? 379 THR D CB    1 
ATOM   6193 O OG1   . THR B 2 379 ? 108.727 134.824 105.475 1.00 96.12  ? 379 THR D OG1   1 
ATOM   6194 C CG2   . THR B 2 379 ? 107.008 133.900 106.754 1.00 96.12  ? 379 THR D CG2   1 
ATOM   6195 N N     . GLN B 2 380 ? 109.345 132.321 109.041 1.00 71.76  ? 380 GLN D N     1 
ATOM   6196 C CA    . GLN B 2 380 ? 108.985 131.432 110.136 1.00 71.76  ? 380 GLN D CA    1 
ATOM   6197 C C     . GLN B 2 380 ? 109.314 132.057 111.469 1.00 71.76  ? 380 GLN D C     1 
ATOM   6198 O O     . GLN B 2 380 ? 108.535 131.953 112.420 1.00 71.76  ? 380 GLN D O     1 
ATOM   6199 C CB    . GLN B 2 380 ? 109.669 130.095 109.981 1.00 100.24 ? 380 GLN D CB    1 
ATOM   6200 C CG    . GLN B 2 380 ? 109.189 129.303 108.839 1.00 100.24 ? 380 GLN D CG    1 
ATOM   6201 C CD    . GLN B 2 380 ? 109.877 128.022 108.746 1.00 100.24 ? 380 GLN D CD    1 
ATOM   6202 O OE1   . GLN B 2 380 ? 110.985 127.893 109.225 1.00 100.24 ? 380 GLN D OE1   1 
ATOM   6203 N NE2   . GLN B 2 380 ? 109.250 127.049 108.127 1.00 100.24 ? 380 GLN D NE2   1 
ATOM   6204 N N     . PHE B 2 381 ? 110.460 132.710 111.558 1.00 74.46  ? 381 PHE D N     1 
ATOM   6205 C CA    . PHE B 2 381 ? 110.864 133.366 112.780 1.00 74.46  ? 381 PHE D CA    1 
ATOM   6206 C C     . PHE B 2 381 ? 109.830 134.331 113.205 1.00 74.46  ? 381 PHE D C     1 
ATOM   6207 O O     . PHE B 2 381 ? 109.379 134.294 114.343 1.00 74.46  ? 381 PHE D O     1 
ATOM   6208 C CB    . PHE B 2 381 ? 112.149 134.124 112.581 1.00 103.86 ? 381 PHE D CB    1 
ATOM   6209 C CG    . PHE B 2 381 ? 112.564 134.917 113.739 1.00 103.86 ? 381 PHE D CG    1 
ATOM   6210 C CD1   . PHE B 2 381 ? 112.165 136.180 113.906 1.00 103.86 ? 381 PHE D CD1   1 
ATOM   6211 C CD2   . PHE B 2 381 ? 113.386 134.392 114.618 1.00 103.86 ? 381 PHE D CD2   1 
ATOM   6212 C CE1   . PHE B 2 381 ? 112.571 136.887 114.960 1.00 103.86 ? 381 PHE D CE1   1 
ATOM   6213 C CE2   . PHE B 2 381 ? 113.809 135.074 115.668 1.00 103.86 ? 381 PHE D CE2   1 
ATOM   6214 C CZ    . PHE B 2 381 ? 113.393 136.326 115.855 1.00 103.86 ? 381 PHE D CZ    1 
ATOM   6215 N N     . GLU B 2 382 ? 109.416 135.195 112.305 1.00 73.47  ? 382 GLU D N     1 
ATOM   6216 C CA    . GLU B 2 382 ? 108.484 136.232 112.687 1.00 73.47  ? 382 GLU D CA    1 
ATOM   6217 C C     . GLU B 2 382 ? 107.155 135.657 113.111 1.00 73.47  ? 382 GLU D C     1 
ATOM   6218 O O     . GLU B 2 382 ? 106.551 136.117 114.080 1.00 73.47  ? 382 GLU D O     1 
ATOM   6219 C CB    . GLU B 2 382 ? 108.274 137.189 111.548 1.00 98.68  ? 382 GLU D CB    1 
ATOM   6220 C CG    . GLU B 2 382 ? 109.452 138.067 111.259 1.00 98.68  ? 382 GLU D CG    1 
ATOM   6221 C CD    . GLU B 2 382 ? 109.195 138.975 110.095 1.00 98.68  ? 382 GLU D CD    1 
ATOM   6222 O OE1   . GLU B 2 382 ? 108.180 138.786 109.427 1.00 98.68  ? 382 GLU D OE1   1 
ATOM   6223 O OE2   . GLU B 2 382 ? 109.993 139.875 109.844 1.00 98.68  ? 382 GLU D OE2   1 
ATOM   6224 N N     . LEU B 2 383 ? 106.682 134.647 112.418 1.00 70.88  ? 383 LEU D N     1 
ATOM   6225 C CA    . LEU B 2 383 ? 105.382 134.096 112.752 1.00 70.88  ? 383 LEU D CA    1 
ATOM   6226 C C     . LEU B 2 383 ? 105.368 133.518 114.150 1.00 70.88  ? 383 LEU D C     1 
ATOM   6227 O O     . LEU B 2 383 ? 104.449 133.766 114.920 1.00 70.88  ? 383 LEU D O     1 
ATOM   6228 C CB    . LEU B 2 383 ? 105.053 133.083 111.696 1.00 104.88 ? 383 LEU D CB    1 
ATOM   6229 C CG    . LEU B 2 383 ? 103.786 132.347 111.772 1.00 104.88 ? 383 LEU D CG    1 
ATOM   6230 C CD1   . LEU B 2 383 ? 102.608 133.276 111.805 1.00 104.88 ? 383 LEU D CD1   1 
ATOM   6231 C CD2   . LEU B 2 383 ? 103.728 131.472 110.557 1.00 104.88 ? 383 LEU D CD2   1 
ATOM   6232 N N     . MET B 2 384 ? 106.413 132.791 114.518 1.00 73.78  ? 384 MET D N     1 
ATOM   6233 C CA    . MET B 2 384 ? 106.514 132.263 115.865 1.00 73.78  ? 384 MET D CA    1 
ATOM   6234 C C     . MET B 2 384 ? 106.786 133.356 116.869 1.00 73.78  ? 384 MET D C     1 
ATOM   6235 O O     . MET B 2 384 ? 106.254 133.342 117.977 1.00 73.78  ? 384 MET D O     1 
ATOM   6236 C CB    . MET B 2 384 ? 107.637 131.234 115.953 1.00 105.96 ? 384 MET D CB    1 
ATOM   6237 C CG    . MET B 2 384 ? 107.425 129.984 115.238 1.00 105.96 ? 384 MET D CG    1 
ATOM   6238 S SD    . MET B 2 384 ? 108.845 128.948 115.206 1.00 105.96 ? 384 MET D SD    1 
ATOM   6239 C CE    . MET B 2 384 ? 108.952 128.411 116.857 1.00 105.96 ? 384 MET D CE    1 
ATOM   6240 N N     . TYR B 2 385 ? 107.659 134.277 116.517 1.00 72.88  ? 385 TYR D N     1 
ATOM   6241 C CA    . TYR B 2 385 ? 108.103 135.286 117.447 1.00 72.88  ? 385 TYR D CA    1 
ATOM   6242 C C     . TYR B 2 385 ? 106.971 136.148 117.883 1.00 72.88  ? 385 TYR D C     1 
ATOM   6243 O O     . TYR B 2 385 ? 106.839 136.445 119.064 1.00 72.88  ? 385 TYR D O     1 
ATOM   6244 C CB    . TYR B 2 385 ? 109.178 136.157 116.853 1.00 100.87 ? 385 TYR D CB    1 
ATOM   6245 C CG    . TYR B 2 385 ? 109.643 137.081 117.873 1.00 100.87 ? 385 TYR D CG    1 
ATOM   6246 C CD1   . TYR B 2 385 ? 110.479 136.655 118.824 1.00 100.87 ? 385 TYR D CD1   1 
ATOM   6247 C CD2   . TYR B 2 385 ? 109.237 138.351 117.884 1.00 100.87 ? 385 TYR D CD2   1 
ATOM   6248 C CE1   . TYR B 2 385 ? 110.893 137.471 119.778 1.00 100.87 ? 385 TYR D CE1   1 
ATOM   6249 C CE2   . TYR B 2 385 ? 109.656 139.186 118.824 1.00 100.87 ? 385 TYR D CE2   1 
ATOM   6250 C CZ    . TYR B 2 385 ? 110.489 138.750 119.774 1.00 100.87 ? 385 TYR D CZ    1 
ATOM   6251 O OH    . TYR B 2 385 ? 110.896 139.605 120.762 1.00 100.87 ? 385 TYR D OH    1 
ATOM   6252 N N     . ASP B 2 386 ? 106.109 136.506 116.966 1.00 71.44  ? 386 ASP D N     1 
ATOM   6253 C CA    . ASP B 2 386 ? 105.007 137.391 117.277 1.00 71.44  ? 386 ASP D CA    1 
ATOM   6254 C C     . ASP B 2 386 ? 104.030 136.804 118.289 1.00 71.44  ? 386 ASP D C     1 
ATOM   6255 O O     . ASP B 2 386 ? 103.210 137.541 118.832 1.00 71.44  ? 386 ASP D O     1 
ATOM   6256 C CB    . ASP B 2 386 ? 104.241 137.749 116.014 1.00 91.85  ? 386 ASP D CB    1 
ATOM   6257 C CG    . ASP B 2 386 ? 104.963 138.761 115.130 1.00 91.85  ? 386 ASP D CG    1 
ATOM   6258 O OD1   . ASP B 2 386 ? 105.948 139.370 115.556 1.00 91.85  ? 386 ASP D OD1   1 
ATOM   6259 O OD2   . ASP B 2 386 ? 104.512 138.965 113.999 1.00 91.85  ? 386 ASP D OD2   1 
ATOM   6260 N N     . HIS B 2 387 ? 104.051 135.510 118.530 1.00 68.09  ? 387 HIS D N     1 
ATOM   6261 C CA    . HIS B 2 387 ? 103.180 134.915 119.516 1.00 68.09  ? 387 HIS D CA    1 
ATOM   6262 C C     . HIS B 2 387 ? 103.969 134.340 120.662 1.00 68.09  ? 387 HIS D C     1 
ATOM   6263 O O     . HIS B 2 387 ? 103.435 133.569 121.440 1.00 68.09  ? 387 HIS D O     1 
ATOM   6264 C CB    . HIS B 2 387 ? 102.350 133.842 118.868 1.00 92.59  ? 387 HIS D CB    1 
ATOM   6265 C CG    . HIS B 2 387 ? 101.492 134.367 117.804 1.00 92.59  ? 387 HIS D CG    1 
ATOM   6266 N ND1   . HIS B 2 387 ? 101.908 134.496 116.506 1.00 92.59  ? 387 HIS D ND1   1 
ATOM   6267 C CD2   . HIS B 2 387 ? 100.241 134.834 117.850 1.00 92.59  ? 387 HIS D CD2   1 
ATOM   6268 C CE1   . HIS B 2 387 ? 100.932 135.013 115.794 1.00 92.59  ? 387 HIS D CE1   1 
ATOM   6269 N NE2   . HIS B 2 387 ? 99.907  135.221 116.589 1.00 92.59  ? 387 HIS D NE2   1 
ATOM   6270 N N     . ASP B 2 388 ? 105.234 134.686 120.752 1.00 71.55  ? 388 ASP D N     1 
ATOM   6271 C CA    . ASP B 2 388 ? 106.160 134.236 121.774 1.00 71.55  ? 388 ASP D CA    1 
ATOM   6272 C C     . ASP B 2 388 ? 106.238 132.731 121.871 1.00 71.55  ? 388 ASP D C     1 
ATOM   6273 O O     . ASP B 2 388 ? 106.468 132.179 122.936 1.00 71.55  ? 388 ASP D O     1 
ATOM   6274 C CB    . ASP B 2 388 ? 105.821 134.816 123.131 1.00 91.99  ? 388 ASP D CB    1 
ATOM   6275 C CG    . ASP B 2 388 ? 106.181 136.263 123.269 1.00 91.99  ? 388 ASP D CG    1 
ATOM   6276 O OD1   . ASP B 2 388 ? 107.260 136.656 122.845 1.00 91.99  ? 388 ASP D OD1   1 
ATOM   6277 O OD2   . ASP B 2 388 ? 105.378 137.015 123.821 1.00 91.99  ? 388 ASP D OD2   1 
ATOM   6278 N N     . ALA B 2 389 ? 106.109 132.038 120.778 1.00 72.72  ? 389 ALA D N     1 
ATOM   6279 C CA    . ALA B 2 389 ? 106.166 130.613 120.920 1.00 72.72  ? 389 ALA D CA    1 
ATOM   6280 C C     . ALA B 2 389 ? 107.588 130.207 121.139 1.00 72.72  ? 389 ALA D C     1 
ATOM   6281 O O     . ALA B 2 389 ? 108.447 130.505 120.332 1.00 72.72  ? 389 ALA D O     1 
ATOM   6282 C CB    . ALA B 2 389 ? 105.582 129.909 119.713 1.00 99.16  ? 389 ALA D CB    1 
ATOM   6283 N N     . PHE B 2 390 ? 107.826 129.524 122.209 1.00 77.13  ? 390 PHE D N     1 
ATOM   6284 C CA    . PHE B 2 390 ? 109.115 129.003 122.552 1.00 77.13  ? 390 PHE D CA    1 
ATOM   6285 C C     . PHE B 2 390 ? 110.099 130.077 122.882 1.00 77.13  ? 390 PHE D C     1 
ATOM   6286 O O     . PHE B 2 390 ? 111.296 129.807 122.904 1.00 77.13  ? 390 PHE D O     1 
ATOM   6287 C CB    . PHE B 2 390 ? 109.697 128.141 121.456 1.00 107.58 ? 390 PHE D CB    1 
ATOM   6288 C CG    . PHE B 2 390 ? 108.847 127.047 121.009 1.00 107.58 ? 390 PHE D CG    1 
ATOM   6289 C CD1   . PHE B 2 390 ? 108.867 125.849 121.620 1.00 107.58 ? 390 PHE D CD1   1 
ATOM   6290 C CD2   . PHE B 2 390 ? 108.071 127.201 119.943 1.00 107.58 ? 390 PHE D CD2   1 
ATOM   6291 C CE1   . PHE B 2 390 ? 108.085 124.844 121.168 1.00 107.58 ? 390 PHE D CE1   1 
ATOM   6292 C CE2   . PHE B 2 390 ? 107.309 126.207 119.474 1.00 107.58 ? 390 PHE D CE2   1 
ATOM   6293 C CZ    . PHE B 2 390 ? 107.305 125.029 120.082 1.00 107.58 ? 390 PHE D CZ    1 
ATOM   6294 N N     . THR B 2 391 ? 109.670 131.278 123.190 1.00 77.47  ? 391 THR D N     1 
ATOM   6295 C CA    . THR B 2 391 ? 110.663 132.290 123.472 1.00 77.47  ? 391 THR D CA    1 
ATOM   6296 C C     . THR B 2 391 ? 111.085 132.318 124.910 1.00 77.47  ? 391 THR D C     1 
ATOM   6297 O O     . THR B 2 391 ? 112.206 132.741 125.206 1.00 77.47  ? 391 THR D O     1 
ATOM   6298 C CB    . THR B 2 391 ? 110.173 133.662 123.073 1.00 108.44 ? 391 THR D CB    1 
ATOM   6299 O OG1   . THR B 2 391 ? 108.978 133.953 123.789 1.00 108.44 ? 391 THR D OG1   1 
ATOM   6300 C CG2   . THR B 2 391 ? 109.891 133.693 121.572 1.00 108.44 ? 391 THR D CG2   1 
ATOM   6301 N N     . THR B 2 392 ? 110.283 131.732 125.785 1.00 79.72  ? 392 THR D N     1 
ATOM   6302 C CA    . THR B 2 392 ? 110.577 131.718 127.210 1.00 79.72  ? 392 THR D CA    1 
ATOM   6303 C C     . THR B 2 392 ? 111.830 130.949 127.497 1.00 79.72  ? 392 THR D C     1 
ATOM   6304 O O     . THR B 2 392 ? 112.561 131.269 128.434 1.00 79.72  ? 392 THR D O     1 
ATOM   6305 C CB    . THR B 2 392 ? 109.418 131.127 127.975 1.00 111.59 ? 392 THR D CB    1 
ATOM   6306 O OG1   . THR B 2 392 ? 109.633 131.333 129.354 1.00 111.59 ? 392 THR D OG1   1 
ATOM   6307 C CG2   . THR B 2 392 ? 109.280 129.619 127.728 1.00 111.59 ? 392 THR D CG2   1 
ATOM   6308 N N     . TRP B 2 393 ? 112.111 129.961 126.679 1.00 78.50  ? 393 TRP D N     1 
ATOM   6309 C CA    . TRP B 2 393 ? 113.245 129.108 126.888 1.00 78.50  ? 393 TRP D CA    1 
ATOM   6310 C C     . TRP B 2 393 ? 114.544 129.827 126.653 1.00 78.50  ? 393 TRP D C     1 
ATOM   6311 O O     . TRP B 2 393 ? 115.571 129.409 127.179 1.00 78.50  ? 393 TRP D O     1 
ATOM   6312 C CB    . TRP B 2 393 ? 113.146 127.899 125.978 1.00 108.64 ? 393 TRP D CB    1 
ATOM   6313 C CG    . TRP B 2 393 ? 111.930 127.173 126.184 1.00 108.64 ? 393 TRP D CG    1 
ATOM   6314 C CD1   . TRP B 2 393 ? 110.980 126.986 125.316 1.00 108.64 ? 393 TRP D CD1   1 
ATOM   6315 C CD2   . TRP B 2 393 ? 111.514 126.545 127.369 1.00 108.64 ? 393 TRP D CD2   1 
ATOM   6316 N NE1   . TRP B 2 393 ? 109.985 126.282 125.858 1.00 108.64 ? 393 TRP D NE1   1 
ATOM   6317 C CE2   . TRP B 2 393 ? 110.303 126.028 127.142 1.00 108.64 ? 393 TRP D CE2   1 
ATOM   6318 C CE3   . TRP B 2 393 ? 112.053 126.406 128.608 1.00 108.64 ? 393 TRP D CE3   1 
ATOM   6319 C CZ2   . TRP B 2 393 ? 109.614 125.377 128.065 1.00 108.64 ? 393 TRP D CZ2   1 
ATOM   6320 C CZ3   . TRP B 2 393 ? 111.347 125.758 129.543 1.00 108.64 ? 393 TRP D CZ3   1 
ATOM   6321 C CH2   . TRP B 2 393 ? 110.155 125.253 129.272 1.00 108.64 ? 393 TRP D CH2   1 
ATOM   6322 N N     . TYR B 2 394 ? 114.541 130.863 125.872 1.00 81.58  ? 394 TYR D N     1 
ATOM   6323 C CA    . TYR B 2 394 ? 115.758 131.569 125.642 1.00 81.58  ? 394 TYR D CA    1 
ATOM   6324 C C     . TYR B 2 394 ? 115.902 132.669 126.644 1.00 81.58  ? 394 TYR D C     1 
ATOM   6325 O O     . TYR B 2 394 ? 117.014 132.979 127.082 1.00 81.58  ? 394 TYR D O     1 
ATOM   6326 C CB    . TYR B 2 394 ? 115.747 132.191 124.272 1.00 112.92 ? 394 TYR D CB    1 
ATOM   6327 C CG    . TYR B 2 394 ? 115.700 131.300 123.139 1.00 112.92 ? 394 TYR D CG    1 
ATOM   6328 C CD1   . TYR B 2 394 ? 114.545 130.821 122.721 1.00 112.92 ? 394 TYR D CD1   1 
ATOM   6329 C CD2   . TYR B 2 394 ? 116.804 131.008 122.450 1.00 112.92 ? 394 TYR D CD2   1 
ATOM   6330 C CE1   . TYR B 2 394 ? 114.488 130.048 121.677 1.00 112.92 ? 394 TYR D CE1   1 
ATOM   6331 C CE2   . TYR B 2 394 ? 116.756 130.236 121.395 1.00 112.92 ? 394 TYR D CE2   1 
ATOM   6332 C CZ    . TYR B 2 394 ? 115.601 129.775 121.001 1.00 112.92 ? 394 TYR D CZ    1 
ATOM   6333 O OH    . TYR B 2 394 ? 115.530 128.986 119.899 1.00 112.92 ? 394 TYR D OH    1 
ATOM   6334 N N     . TYR B 2 395 ? 114.783 133.263 127.017 1.00 82.03  ? 395 TYR D N     1 
ATOM   6335 C CA    . TYR B 2 395 ? 114.824 134.391 127.916 1.00 82.03  ? 395 TYR D CA    1 
ATOM   6336 C C     . TYR B 2 395 ? 115.406 133.963 129.239 1.00 82.03  ? 395 TYR D C     1 
ATOM   6337 O O     . TYR B 2 395 ? 116.187 134.697 129.842 1.00 82.03  ? 395 TYR D O     1 
ATOM   6338 C CB    . TYR B 2 395 ? 113.440 134.988 128.099 1.00 113.54 ? 395 TYR D CB    1 
ATOM   6339 C CG    . TYR B 2 395 ? 112.772 135.570 126.864 1.00 113.54 ? 395 TYR D CG    1 
ATOM   6340 C CD1   . TYR B 2 395 ? 113.474 135.957 125.761 1.00 113.54 ? 395 TYR D CD1   1 
ATOM   6341 C CD2   . TYR B 2 395 ? 111.408 135.721 126.827 1.00 113.54 ? 395 TYR D CD2   1 
ATOM   6342 C CE1   . TYR B 2 395 ? 112.840 136.471 124.673 1.00 113.54 ? 395 TYR D CE1   1 
ATOM   6343 C CE2   . TYR B 2 395 ? 110.780 136.233 125.739 1.00 113.54 ? 395 TYR D CE2   1 
ATOM   6344 C CZ    . TYR B 2 395 ? 111.500 136.597 124.670 1.00 113.54 ? 395 TYR D CZ    1 
ATOM   6345 O OH    . TYR B 2 395 ? 110.859 137.120 123.568 1.00 113.54 ? 395 TYR D OH    1 
ATOM   6346 N N     . GLN B 2 396 ? 115.095 132.750 129.686 1.00 82.46  ? 396 GLN D N     1 
ATOM   6347 C CA    . GLN B 2 396 ? 115.597 132.305 130.982 1.00 82.46  ? 396 GLN D CA    1 
ATOM   6348 C C     . GLN B 2 396 ? 117.073 131.948 130.976 1.00 82.46  ? 396 GLN D C     1 
ATOM   6349 O O     . GLN B 2 396 ? 117.625 131.691 132.038 1.00 82.46  ? 396 GLN D O     1 
ATOM   6350 C CB    . GLN B 2 396 ? 114.792 131.127 131.514 1.00 115.19 ? 396 GLN D CB    1 
ATOM   6351 C CG    . GLN B 2 396 ? 114.955 129.862 130.816 1.00 115.19 ? 396 GLN D CG    1 
ATOM   6352 C CD    . GLN B 2 396 ? 114.216 128.784 131.506 1.00 115.19 ? 396 GLN D CD    1 
ATOM   6353 O OE1   . GLN B 2 396 ? 113.490 129.037 132.457 1.00 115.19 ? 396 GLN D OE1   1 
ATOM   6354 N NE2   . GLN B 2 396 ? 114.400 127.555 131.050 1.00 115.19 ? 396 GLN D NE2   1 
ATOM   6355 N N     . GLU B 2 397 ? 117.714 131.882 129.823 1.00 84.67  ? 397 GLU D N     1 
ATOM   6356 C CA    . GLU B 2 397 ? 119.135 131.619 129.733 1.00 84.67  ? 397 GLU D CA    1 
ATOM   6357 C C     . GLU B 2 397 ? 119.910 132.893 129.543 1.00 84.67  ? 397 GLU D C     1 
ATOM   6358 O O     . GLU B 2 397 ? 121.121 132.847 129.359 1.00 84.67  ? 397 GLU D O     1 
ATOM   6359 C CB    . GLU B 2 397 ? 119.451 130.685 128.570 1.00 113.72 ? 397 GLU D CB    1 
ATOM   6360 C CG    . GLU B 2 397 ? 118.798 129.360 128.623 1.00 113.72 ? 397 GLU D CG    1 
ATOM   6361 C CD    . GLU B 2 397 ? 119.251 128.543 129.770 1.00 113.72 ? 397 GLU D CD    1 
ATOM   6362 O OE1   . GLU B 2 397 ? 120.438 128.574 130.113 1.00 113.72 ? 397 GLU D OE1   1 
ATOM   6363 O OE2   . GLU B 2 397 ? 118.425 127.813 130.317 1.00 113.72 ? 397 GLU D OE2   1 
ATOM   6364 N N     . GLY B 2 398 ? 119.250 134.034 129.541 1.00 84.78  ? 398 GLY D N     1 
ATOM   6365 C CA    . GLY B 2 398 ? 119.928 135.298 129.356 1.00 84.78  ? 398 GLY D CA    1 
ATOM   6366 C C     . GLY B 2 398 ? 119.648 136.020 128.058 1.00 84.78  ? 398 GLY D C     1 
ATOM   6367 O O     . GLY B 2 398 ? 120.187 137.108 127.853 1.00 84.78  ? 398 GLY D O     1 
ATOM   6368 N N     . MET B 2 399 ? 118.816 135.512 127.182 1.00 83.29  ? 399 MET D N     1 
ATOM   6369 C CA    . MET B 2 399 ? 118.616 136.262 125.955 1.00 83.29  ? 399 MET D CA    1 
ATOM   6370 C C     . MET B 2 399 ? 117.538 137.295 126.071 1.00 83.29  ? 399 MET D C     1 
ATOM   6371 O O     . MET B 2 399 ? 116.408 137.094 125.640 1.00 83.29  ? 399 MET D O     1 
ATOM   6372 C CB    . MET B 2 399 ? 118.310 135.352 124.798 1.00 119.61 ? 399 MET D CB    1 
ATOM   6373 C CG    . MET B 2 399 ? 119.489 134.610 124.430 1.00 119.61 ? 399 MET D CG    1 
ATOM   6374 S SD    . MET B 2 399 ? 119.284 133.667 122.968 1.00 119.61 ? 399 MET D SD    1 
ATOM   6375 C CE    . MET B 2 399 ? 119.410 134.919 121.748 1.00 119.61 ? 399 MET D CE    1 
ATOM   6376 N N     . GLN B 2 400 ? 117.921 138.435 126.561 1.00 79.61  ? 400 GLN D N     1 
ATOM   6377 C CA    . GLN B 2 400 ? 116.996 139.539 126.651 1.00 79.61  ? 400 GLN D CA    1 
ATOM   6378 C C     . GLN B 2 400 ? 116.324 139.701 125.293 1.00 79.61  ? 400 GLN D C     1 
ATOM   6379 O O     . GLN B 2 400 ? 117.021 139.673 124.283 1.00 79.61  ? 400 GLN D O     1 
ATOM   6380 C CB    . GLN B 2 400 ? 117.780 140.785 127.034 1.00 111.21 ? 400 GLN D CB    1 
ATOM   6381 C CG    . GLN B 2 400 ? 117.000 142.005 127.253 1.00 111.21 ? 400 GLN D CG    1 
ATOM   6382 C CD    . GLN B 2 400 ? 117.888 143.169 127.554 1.00 111.21 ? 400 GLN D CD    1 
ATOM   6383 O OE1   . GLN B 2 400 ? 119.111 143.047 127.530 1.00 111.21 ? 400 GLN D OE1   1 
ATOM   6384 N NE2   . GLN B 2 400 ? 117.285 144.313 127.849 1.00 111.21 ? 400 GLN D NE2   1 
ATOM   6385 N N     . PRO B 2 401 ? 115.001 139.901 125.236 1.00 78.47  ? 401 PRO D N     1 
ATOM   6386 C CA    . PRO B 2 401 ? 114.229 139.935 123.986 1.00 78.47  ? 401 PRO D CA    1 
ATOM   6387 C C     . PRO B 2 401 ? 114.664 140.938 122.950 1.00 78.47  ? 401 PRO D C     1 
ATOM   6388 O O     . PRO B 2 401 ? 114.376 140.739 121.765 1.00 78.47  ? 401 PRO D O     1 
ATOM   6389 C CB    . PRO B 2 401 ? 112.830 140.272 124.473 1.00 244.76 ? 401 PRO D CB    1 
ATOM   6390 C CG    . PRO B 2 401 ? 113.023 140.830 125.791 1.00 244.76 ? 401 PRO D CG    1 
ATOM   6391 C CD    . PRO B 2 401 ? 114.157 140.091 126.388 1.00 244.76 ? 401 PRO D CD    1 
ATOM   6392 N N     . SER B 2 402 ? 115.382 141.984 123.327 1.00 78.62  ? 402 SER D N     1 
ATOM   6393 C CA    . SER B 2 402 ? 115.874 142.935 122.341 1.00 78.62  ? 402 SER D CA    1 
ATOM   6394 C C     . SER B 2 402 ? 116.837 142.275 121.382 1.00 78.62  ? 402 SER D C     1 
ATOM   6395 O O     . SER B 2 402 ? 117.074 142.797 120.286 1.00 78.62  ? 402 SER D O     1 
ATOM   6396 C CB    . SER B 2 402 ? 116.563 144.081 123.037 1.00 105.89 ? 402 SER D CB    1 
ATOM   6397 O OG    . SER B 2 402 ? 117.743 143.634 123.645 1.00 105.89 ? 402 SER D OG    1 
ATOM   6398 N N     . GLU B 2 403 ? 117.366 141.125 121.772 1.00 81.38  ? 403 GLU D N     1 
ATOM   6399 C CA    . GLU B 2 403 ? 118.252 140.321 120.956 1.00 81.38  ? 403 GLU D CA    1 
ATOM   6400 C C     . GLU B 2 403 ? 117.521 139.693 119.792 1.00 81.38  ? 403 GLU D C     1 
ATOM   6401 O O     . GLU B 2 403 ? 118.090 139.523 118.714 1.00 81.38  ? 403 GLU D O     1 
ATOM   6402 C CB    . GLU B 2 403 ? 118.836 139.248 121.839 1.00 109.30 ? 403 GLU D CB    1 
ATOM   6403 C CG    . GLU B 2 403 ? 119.743 138.280 121.190 1.00 109.30 ? 403 GLU D CG    1 
ATOM   6404 C CD    . GLU B 2 403 ? 120.994 138.866 120.639 1.00 109.30 ? 403 GLU D CD    1 
ATOM   6405 O OE1   . GLU B 2 403 ? 121.398 139.959 121.035 1.00 109.30 ? 403 GLU D OE1   1 
ATOM   6406 O OE2   . GLU B 2 403 ? 121.589 138.194 119.798 1.00 109.30 ? 403 GLU D OE2   1 
ATOM   6407 N N     . PHE B 2 404 ? 116.290 139.294 120.002 1.00 77.41  ? 404 PHE D N     1 
ATOM   6408 C CA    . PHE B 2 404 ? 115.534 138.699 118.938 1.00 77.41  ? 404 PHE D CA    1 
ATOM   6409 C C     . PHE B 2 404 ? 115.154 139.754 117.932 1.00 77.41  ? 404 PHE D C     1 
ATOM   6410 O O     . PHE B 2 404 ? 115.198 139.519 116.716 1.00 77.41  ? 404 PHE D O     1 
ATOM   6411 C CB    . PHE B 2 404 ? 114.294 138.029 119.506 1.00 107.97 ? 404 PHE D CB    1 
ATOM   6412 C CG    . PHE B 2 404 ? 114.524 136.691 120.059 1.00 107.97 ? 404 PHE D CG    1 
ATOM   6413 C CD1   . PHE B 2 404 ? 115.217 136.513 121.205 1.00 107.97 ? 404 PHE D CD1   1 
ATOM   6414 C CD2   . PHE B 2 404 ? 114.023 135.625 119.457 1.00 107.97 ? 404 PHE D CD2   1 
ATOM   6415 C CE1   . PHE B 2 404 ? 115.411 135.281 121.685 1.00 107.97 ? 404 PHE D CE1   1 
ATOM   6416 C CE2   . PHE B 2 404 ? 114.206 134.424 119.939 1.00 107.97 ? 404 PHE D CE2   1 
ATOM   6417 C CZ    . PHE B 2 404 ? 114.898 134.251 121.052 1.00 107.97 ? 404 PHE D CZ    1 
ATOM   6418 N N     . GLU B 2 405 ? 114.807 140.927 118.415 1.00 77.83  ? 405 GLU D N     1 
ATOM   6419 C CA    . GLU B 2 405 ? 114.441 142.000 117.521 1.00 77.83  ? 405 GLU D CA    1 
ATOM   6420 C C     . GLU B 2 405 ? 115.625 142.399 116.673 1.00 77.83  ? 405 GLU D C     1 
ATOM   6421 O O     . GLU B 2 405 ? 115.490 142.614 115.463 1.00 77.83  ? 405 GLU D O     1 
ATOM   6422 C CB    . GLU B 2 405 ? 113.945 143.195 118.313 1.00 104.54 ? 405 GLU D CB    1 
ATOM   6423 C CG    . GLU B 2 405 ? 113.340 144.310 117.483 1.00 104.54 ? 405 GLU D CG    1 
ATOM   6424 C CD    . GLU B 2 405 ? 112.014 143.931 116.890 1.00 104.54 ? 405 GLU D CD    1 
ATOM   6425 O OE1   . GLU B 2 405 ? 111.439 142.961 117.349 1.00 104.54 ? 405 GLU D OE1   1 
ATOM   6426 O OE2   . GLU B 2 405 ? 111.537 144.596 115.968 1.00 104.54 ? 405 GLU D OE2   1 
ATOM   6427 N N     . ALA B 2 406 ? 116.803 142.472 117.269 1.00 73.90  ? 406 ALA D N     1 
ATOM   6428 C CA    . ALA B 2 406 ? 117.978 142.823 116.498 1.00 73.90  ? 406 ALA D CA    1 
ATOM   6429 C C     . ALA B 2 406 ? 118.280 141.793 115.427 1.00 73.90  ? 406 ALA D C     1 
ATOM   6430 O O     . ALA B 2 406 ? 118.602 142.162 114.297 1.00 73.90  ? 406 ALA D O     1 
ATOM   6431 C CB    . ALA B 2 406 ? 119.169 142.973 117.402 1.00 100.77 ? 406 ALA D CB    1 
ATOM   6432 N N     . ALA B 2 407 ? 118.161 140.510 115.729 1.00 73.80  ? 407 ALA D N     1 
ATOM   6433 C CA    . ALA B 2 407 ? 118.436 139.517 114.710 1.00 73.80  ? 407 ALA D CA    1 
ATOM   6434 C C     . ALA B 2 407 ? 117.481 139.657 113.553 1.00 73.80  ? 407 ALA D C     1 
ATOM   6435 O O     . ALA B 2 407 ? 117.882 139.559 112.387 1.00 73.80  ? 407 ALA D O     1 
ATOM   6436 C CB    . ALA B 2 407 ? 118.351 138.121 115.294 1.00 100.64 ? 407 ALA D CB    1 
ATOM   6437 N N     . LYS B 2 408 ? 116.221 139.896 113.856 1.00 73.33  ? 408 LYS D N     1 
ATOM   6438 C CA    . LYS B 2 408 ? 115.234 140.045 112.812 1.00 73.33  ? 408 LYS D CA    1 
ATOM   6439 C C     . LYS B 2 408 ? 115.617 141.170 111.904 1.00 73.33  ? 408 LYS D C     1 
ATOM   6440 O O     . LYS B 2 408 ? 115.551 141.042 110.687 1.00 73.33  ? 408 LYS D O     1 
ATOM   6441 C CB    . LYS B 2 408 ? 113.871 140.320 113.409 1.00 109.90 ? 408 LYS D CB    1 
ATOM   6442 C CG    . LYS B 2 408 ? 112.760 140.475 112.425 1.00 109.90 ? 408 LYS D CG    1 
ATOM   6443 C CD    . LYS B 2 408 ? 111.455 140.839 113.104 1.00 109.90 ? 408 LYS D CD    1 
ATOM   6444 C CE    . LYS B 2 408 ? 111.550 142.184 113.801 1.00 109.90 ? 408 LYS D CE    1 
ATOM   6445 N NZ    . LYS B 2 408 ? 110.244 142.719 114.265 1.00 109.90 ? 408 LYS D NZ    1 
ATOM   6446 N N     . ASN B 2 409 ? 116.036 142.279 112.481 1.00 73.21  ? 409 ASN D N     1 
ATOM   6447 C CA    . ASN B 2 409 ? 116.369 143.432 111.668 1.00 73.21  ? 409 ASN D CA    1 
ATOM   6448 C C     . ASN B 2 409 ? 117.591 143.212 110.812 1.00 73.21  ? 409 ASN D C     1 
ATOM   6449 O O     . ASN B 2 409 ? 117.615 143.634 109.656 1.00 73.21  ? 409 ASN D O     1 
ATOM   6450 C CB    . ASN B 2 409 ? 116.569 144.624 112.533 1.00 99.18  ? 409 ASN D CB    1 
ATOM   6451 C CG    . ASN B 2 409 ? 115.292 145.111 113.061 1.00 99.18  ? 409 ASN D CG    1 
ATOM   6452 O OD1   . ASN B 2 409 ? 114.228 144.837 112.499 1.00 99.18  ? 409 ASN D OD1   1 
ATOM   6453 N ND2   . ASN B 2 409 ? 115.353 145.842 114.144 1.00 99.18  ? 409 ASN D ND2   1 
ATOM   6454 N N     . ASN B 2 410 ? 118.600 142.543 111.326 1.00 74.10  ? 410 ASN D N     1 
ATOM   6455 C CA    . ASN B 2 410 ? 119.776 142.357 110.499 1.00 74.10  ? 410 ASN D CA    1 
ATOM   6456 C C     . ASN B 2 410 ? 119.537 141.403 109.370 1.00 74.10  ? 410 ASN D C     1 
ATOM   6457 O O     . ASN B 2 410 ? 120.087 141.595 108.288 1.00 74.10  ? 410 ASN D O     1 
ATOM   6458 C CB    . ASN B 2 410 ? 120.938 141.911 111.313 1.00 100.38 ? 410 ASN D CB    1 
ATOM   6459 C CG    . ASN B 2 410 ? 121.477 143.027 112.108 1.00 100.38 ? 410 ASN D CG    1 
ATOM   6460 O OD1   . ASN B 2 410 ? 121.396 144.181 111.702 1.00 100.38 ? 410 ASN D OD1   1 
ATOM   6461 N ND2   . ASN B 2 410 ? 122.004 142.723 113.269 1.00 100.38 ? 410 ASN D ND2   1 
ATOM   6462 N N     . ILE B 2 411 ? 118.707 140.397 109.569 1.00 73.67  ? 411 ILE D N     1 
ATOM   6463 C CA    . ILE B 2 411 ? 118.454 139.502 108.464 1.00 73.67  ? 411 ILE D CA    1 
ATOM   6464 C C     . ILE B 2 411 ? 117.507 140.146 107.483 1.00 73.67  ? 411 ILE D C     1 
ATOM   6465 O O     . ILE B 2 411 ? 117.687 139.996 106.280 1.00 73.67  ? 411 ILE D O     1 
ATOM   6466 C CB    . ILE B 2 411 ? 117.989 138.118 108.933 1.00 109.00 ? 411 ILE D CB    1 
ATOM   6467 C CG1   . ILE B 2 411 ? 119.064 137.475 109.779 1.00 109.00 ? 411 ILE D CG1   1 
ATOM   6468 C CG2   . ILE B 2 411 ? 117.638 137.243 107.761 1.00 109.00 ? 411 ILE D CG2   1 
ATOM   6469 C CD1   . ILE B 2 411 ? 120.415 137.324 109.169 1.00 109.00 ? 411 ILE D CD1   1 
ATOM   6470 N N     . GLN B 2 412 ? 116.504 140.890 107.924 1.00 72.72  ? 412 GLN D N     1 
ATOM   6471 C CA    . GLN B 2 412 ? 115.645 141.517 106.929 1.00 72.72  ? 412 GLN D CA    1 
ATOM   6472 C C     . GLN B 2 412 ? 116.452 142.465 106.090 1.00 72.72  ? 412 GLN D C     1 
ATOM   6473 O O     . GLN B 2 412 ? 116.259 142.550 104.870 1.00 72.72  ? 412 GLN D O     1 
ATOM   6474 C CB    . GLN B 2 412 ? 114.496 142.259 107.570 1.00 101.58 ? 412 GLN D CB    1 
ATOM   6475 C CG    . GLN B 2 412 ? 113.521 142.851 106.584 1.00 101.58 ? 412 GLN D CG    1 
ATOM   6476 C CD    . GLN B 2 412 ? 112.750 141.822 105.858 1.00 101.58 ? 412 GLN D CD    1 
ATOM   6477 O OE1   . GLN B 2 412 ? 112.068 141.028 106.472 1.00 101.58 ? 412 GLN D OE1   1 
ATOM   6478 N NE2   . GLN B 2 412 ? 112.830 141.823 104.544 1.00 101.58 ? 412 GLN D NE2   1 
ATOM   6479 N N     . LYS B 2 413 ? 117.390 143.155 106.707 1.00 73.85  ? 413 LYS D N     1 
ATOM   6480 C CA    . LYS B 2 413 ? 118.240 144.061 105.958 1.00 73.85  ? 413 LYS D CA    1 
ATOM   6481 C C     . LYS B 2 413 ? 119.142 143.306 104.996 1.00 73.85  ? 413 LYS D C     1 
ATOM   6482 O O     . LYS B 2 413 ? 119.286 143.718 103.843 1.00 73.85  ? 413 LYS D O     1 
ATOM   6483 C CB    . LYS B 2 413 ? 119.059 144.907 106.909 1.00 110.68 ? 413 LYS D CB    1 
ATOM   6484 C CG    . LYS B 2 413 ? 119.860 145.956 106.267 1.00 110.68 ? 413 LYS D CG    1 
ATOM   6485 C CD    . LYS B 2 413 ? 120.505 146.849 107.291 1.00 110.68 ? 413 LYS D CD    1 
ATOM   6486 C CE    . LYS B 2 413 ? 121.368 147.901 106.622 1.00 110.68 ? 413 LYS D CE    1 
ATOM   6487 N NZ    . LYS B 2 413 ? 122.028 148.796 107.611 1.00 110.68 ? 413 LYS D NZ    1 
ATOM   6488 N N     . LEU B 2 414 ? 119.719 142.180 105.426 1.00 75.62  ? 414 LEU D N     1 
ATOM   6489 C CA    . LEU B 2 414 ? 120.570 141.374 104.554 1.00 75.62  ? 414 LEU D CA    1 
ATOM   6490 C C     . LEU B 2 414 ? 119.798 140.862 103.356 1.00 75.62  ? 414 LEU D C     1 
ATOM   6491 O O     . LEU B 2 414 ? 120.295 140.898 102.226 1.00 75.62  ? 414 LEU D O     1 
ATOM   6492 C CB    . LEU B 2 414 ? 121.149 140.200 105.337 1.00 111.89 ? 414 LEU D CB    1 
ATOM   6493 C CG    . LEU B 2 414 ? 122.136 139.251 104.677 1.00 111.89 ? 414 LEU D CG    1 
ATOM   6494 C CD1   . LEU B 2 414 ? 123.392 140.002 104.261 1.00 111.89 ? 414 LEU D CD1   1 
ATOM   6495 C CD2   . LEU B 2 414 ? 122.456 138.140 105.608 1.00 111.89 ? 414 LEU D CD2   1 
ATOM   6496 N N     . ILE B 2 415 ? 118.579 140.400 103.572 1.00 76.67  ? 415 ILE D N     1 
ATOM   6497 C CA    . ILE B 2 415 ? 117.764 139.902 102.489 1.00 76.67  ? 415 ILE D CA    1 
ATOM   6498 C C     . ILE B 2 415 ? 117.507 140.986 101.508 1.00 76.67  ? 415 ILE D C     1 
ATOM   6499 O O     . ILE B 2 415 ? 117.607 140.780 100.300 1.00 76.67  ? 415 ILE D O     1 
ATOM   6500 C CB    . ILE B 2 415 ? 116.433 139.360 102.990 1.00 113.44 ? 415 ILE D CB    1 
ATOM   6501 C CG1   . ILE B 2 415 ? 116.670 138.127 103.799 1.00 113.44 ? 415 ILE D CG1   1 
ATOM   6502 C CG2   . ILE B 2 415 ? 115.488 139.100 101.849 1.00 113.44 ? 415 ILE D CG2   1 
ATOM   6503 C CD1   . ILE B 2 415 ? 115.486 137.715 104.599 1.00 113.44 ? 415 ILE D CD1   1 
ATOM   6504 N N     . THR B 2 416 ? 117.164 142.155 102.011 1.00 77.46  ? 416 THR D N     1 
ATOM   6505 C CA    . THR B 2 416 ? 116.866 143.272 101.149 1.00 77.46  ? 416 THR D CA    1 
ATOM   6506 C C     . THR B 2 416 ? 118.056 143.624 100.299 1.00 77.46  ? 416 THR D C     1 
ATOM   6507 O O     . THR B 2 416 ? 117.919 143.841 99.102  1.00 77.46  ? 416 THR D O     1 
ATOM   6508 C CB    . THR B 2 416 ? 116.455 144.471 101.966 1.00 108.43 ? 416 THR D CB    1 
ATOM   6509 O OG1   . THR B 2 416 ? 115.307 144.150 102.760 1.00 108.43 ? 416 THR D OG1   1 
ATOM   6510 C CG2   . THR B 2 416 ? 116.119 145.616 101.064 1.00 108.43 ? 416 THR D CG2   1 
ATOM   6511 N N     . GLU B 2 417 ? 119.233 143.651 100.892 1.00 80.84  ? 417 GLU D N     1 
ATOM   6512 C CA    . GLU B 2 417 ? 120.427 143.986 100.141 1.00 80.84  ? 417 GLU D CA    1 
ATOM   6513 C C     . GLU B 2 417 ? 120.713 142.972 99.054  1.00 80.84  ? 417 GLU D C     1 
ATOM   6514 O O     . GLU B 2 417 ? 121.068 143.359 97.950  1.00 80.84  ? 417 GLU D O     1 
ATOM   6515 C CB    . GLU B 2 417 ? 121.614 144.105 101.080 1.00 108.58 ? 417 GLU D CB    1 
ATOM   6516 C CG    . GLU B 2 417 ? 121.544 145.320 101.970 1.00 108.58 ? 417 GLU D CG    1 
ATOM   6517 C CD    . GLU B 2 417 ? 122.598 145.333 103.013 1.00 108.58 ? 417 GLU D CD    1 
ATOM   6518 O OE1   . GLU B 2 417 ? 123.192 144.291 103.242 1.00 108.58 ? 417 GLU D OE1   1 
ATOM   6519 O OE2   . GLU B 2 417 ? 122.844 146.388 103.601 1.00 108.58 ? 417 GLU D OE2   1 
ATOM   6520 N N     . TYR B 2 418 ? 120.537 141.679 99.312  1.00 80.13  ? 418 TYR D N     1 
ATOM   6521 C CA    . TYR B 2 418 ? 120.754 140.730 98.228  1.00 80.13  ? 418 TYR D CA    1 
ATOM   6522 C C     . TYR B 2 418 ? 119.738 140.900 97.113  1.00 80.13  ? 418 TYR D C     1 
ATOM   6523 O O     . TYR B 2 418 ? 120.094 140.874 95.935  1.00 80.13  ? 418 TYR D O     1 
ATOM   6524 C CB    . TYR B 2 418 ? 120.675 139.310 98.704  1.00 110.91 ? 418 TYR D CB    1 
ATOM   6525 C CG    . TYR B 2 418 ? 121.883 138.760 99.267  1.00 110.91 ? 418 TYR D CG    1 
ATOM   6526 C CD1   . TYR B 2 418 ? 122.898 138.411 98.484  1.00 110.91 ? 418 TYR D CD1   1 
ATOM   6527 C CD2   . TYR B 2 418 ? 121.973 138.516 100.596 1.00 110.91 ? 418 TYR D CD2   1 
ATOM   6528 C CE1   . TYR B 2 418 ? 123.990 137.857 98.990  1.00 110.91 ? 418 TYR D CE1   1 
ATOM   6529 C CE2   . TYR B 2 418 ? 123.071 137.972 101.106 1.00 110.91 ? 418 TYR D CE2   1 
ATOM   6530 C CZ    . TYR B 2 418 ? 124.075 137.653 100.297 1.00 110.91 ? 418 TYR D CZ    1 
ATOM   6531 O OH    . TYR B 2 418 ? 125.201 137.087 100.828 1.00 110.91 ? 418 TYR D OH    1 
ATOM   6532 N N     . LYS B 2 419 ? 118.475 141.081 97.443  1.00 80.21  ? 419 LYS D N     1 
ATOM   6533 C CA    . LYS B 2 419 ? 117.491 141.197 96.383  1.00 80.21  ? 419 LYS D CA    1 
ATOM   6534 C C     . LYS B 2 419 ? 117.688 142.461 95.599  1.00 80.21  ? 419 LYS D C     1 
ATOM   6535 O O     . LYS B 2 419 ? 117.424 142.486 94.406  1.00 80.21  ? 419 LYS D O     1 
ATOM   6536 C CB    . LYS B 2 419 ? 116.082 141.111 96.948  1.00 120.21 ? 419 LYS D CB    1 
ATOM   6537 C CG    . LYS B 2 419 ? 115.715 139.710 97.404  1.00 120.21 ? 419 LYS D CG    1 
ATOM   6538 C CD    . LYS B 2 419 ? 114.297 139.632 97.903  1.00 120.21 ? 419 LYS D CD    1 
ATOM   6539 C CE    . LYS B 2 419 ? 113.914 138.207 98.276  1.00 120.21 ? 419 LYS D CE    1 
ATOM   6540 N NZ    . LYS B 2 419 ? 112.501 138.123 98.746  1.00 120.21 ? 419 LYS D NZ    1 
ATOM   6541 N N     . GLN B 2 420 ? 118.217 143.491 96.224  1.00 84.33  ? 420 GLN D N     1 
ATOM   6542 C CA    . GLN B 2 420 ? 118.441 144.758 95.547  1.00 84.33  ? 420 GLN D CA    1 
ATOM   6543 C C     . GLN B 2 420 ? 119.354 144.608 94.348  1.00 84.33  ? 420 GLN D C     1 
ATOM   6544 O O     . GLN B 2 420 ? 119.263 145.396 93.405  1.00 84.33  ? 420 GLN D O     1 
ATOM   6545 C CB    . GLN B 2 420 ? 119.043 145.771 96.523  1.00 117.80 ? 420 GLN D CB    1 
ATOM   6546 C CG    . GLN B 2 420 ? 119.265 147.164 95.962  1.00 117.80 ? 420 GLN D CG    1 
ATOM   6547 C CD    . GLN B 2 420 ? 117.983 147.855 95.576  1.00 117.80 ? 420 GLN D CD    1 
ATOM   6548 O OE1   . GLN B 2 420 ? 117.036 147.909 96.354  1.00 117.80 ? 420 GLN D OE1   1 
ATOM   6549 N NE2   . GLN B 2 420 ? 117.942 148.388 94.361  1.00 117.80 ? 420 GLN D NE2   1 
ATOM   6550 N N     . ASP B 2 421 ? 120.245 143.621 94.352  1.00 88.73  ? 421 ASP D N     1 
ATOM   6551 C CA    . ASP B 2 421 ? 121.164 143.455 93.238  1.00 88.73  ? 421 ASP D CA    1 
ATOM   6552 C C     . ASP B 2 421 ? 120.432 143.086 91.971  1.00 88.73  ? 421 ASP D C     1 
ATOM   6553 O O     . ASP B 2 421 ? 120.994 143.205 90.882  1.00 88.73  ? 421 ASP D O     1 
ATOM   6554 C CB    . ASP B 2 421 ? 122.210 142.380 93.538  1.00 114.08 ? 421 ASP D CB    1 
ATOM   6555 C CG    . ASP B 2 421 ? 123.262 142.813 94.554  1.00 114.08 ? 421 ASP D CG    1 
ATOM   6556 O OD1   . ASP B 2 421 ? 123.417 144.008 94.820  1.00 114.08 ? 421 ASP D OD1   1 
ATOM   6557 O OD2   . ASP B 2 421 ? 123.946 141.932 95.082  1.00 114.08 ? 421 ASP D OD2   1 
ATOM   6558 N N     . GLU B 2 422 ? 119.187 142.661 92.086  1.00 92.50  ? 422 GLU D N     1 
ATOM   6559 C CA    . GLU B 2 422 ? 118.368 142.276 90.945  1.00 92.50  ? 422 GLU D CA    1 
ATOM   6560 C C     . GLU B 2 422 ? 117.643 143.438 90.276  1.00 92.50  ? 422 GLU D C     1 
ATOM   6561 O O     . GLU B 2 422 ? 117.014 143.222 89.231  1.00 92.50  ? 422 GLU D O     1 
ATOM   6562 C CB    . GLU B 2 422 ? 117.308 141.248 91.356  1.00 124.24 ? 422 GLU D CB    1 
ATOM   6563 C CG    . GLU B 2 422 ? 117.860 139.931 91.866  1.00 124.24 ? 422 GLU D CG    1 
ATOM   6564 C CD    . GLU B 2 422 ? 116.791 138.957 92.255  1.00 124.24 ? 422 GLU D CD    1 
ATOM   6565 O OE1   . GLU B 2 422 ? 115.618 139.246 92.039  1.00 124.24 ? 422 GLU D OE1   1 
ATOM   6566 O OE2   . GLU B 2 422 ? 117.133 137.890 92.769  1.00 124.24 ? 422 GLU D OE2   1 
ATOM   6567 N N     . TYR B 2 423 ? 117.702 144.643 90.844  1.00 91.79  ? 423 TYR D N     1 
ATOM   6568 C CA    . TYR B 2 423 ? 116.997 145.828 90.358  1.00 91.79  ? 423 TYR D CA    1 
ATOM   6569 C C     . TYR B 2 423 ? 118.015 146.863 89.882  1.00 91.79  ? 423 TYR D C     1 
ATOM   6570 O O     . TYR B 2 423 ? 117.682 147.832 89.206  1.00 91.79  ? 423 TYR D O     1 
ATOM   6571 C CB    . TYR B 2 423 ? 116.088 146.398 91.474  1.00 127.05 ? 423 TYR D CB    1 
ATOM   6572 C CG    . TYR B 2 423 ? 115.007 145.398 91.973  1.00 127.05 ? 423 TYR D CG    1 
ATOM   6573 C CD1   . TYR B 2 423 ? 115.326 144.436 92.994  1.00 127.05 ? 423 TYR D CD1   1 
ATOM   6574 C CD2   . TYR B 2 423 ? 113.674 145.391 91.420  1.00 127.05 ? 423 TYR D CD2   1 
ATOM   6575 C CE1   . TYR B 2 423 ? 114.353 143.482 93.463  1.00 127.05 ? 423 TYR D CE1   1 
ATOM   6576 C CE2   . TYR B 2 423 ? 112.679 144.434 91.883  1.00 127.05 ? 423 TYR D CE2   1 
ATOM   6577 C CZ    . TYR B 2 423 ? 113.030 143.484 92.904  1.00 127.05 ? 423 TYR D CZ    1 
ATOM   6578 O OH    . TYR B 2 423 ? 112.087 142.562 93.352  1.00 127.05 ? 423 TYR D OH    1 
HETATM 6579 P PG    . GTP C 3 .   ? 96.281  106.520 149.977 1.00 0.05   ? 501 GTP A PG    1 
HETATM 6580 O O1G   . GTP C 3 .   ? 95.443  107.686 149.582 1.00 0.05   ? 501 GTP A O1G   1 
HETATM 6581 O O2G   . GTP C 3 .   ? 95.949  105.221 149.318 1.00 0.05   ? 501 GTP A O2G   1 
HETATM 6582 O O3G   . GTP C 3 .   ? 96.548  106.445 151.436 1.00 0.05   ? 501 GTP A O3G   1 
HETATM 6583 O O3B   . GTP C 3 .   ? 97.707  106.839 149.440 1.00 0.05   ? 501 GTP A O3B   1 
HETATM 6584 P PB    . GTP C 3 .   ? 97.830  106.626 147.896 1.00 0.05   ? 501 GTP A PB    1 
HETATM 6585 O O1B   . GTP C 3 .   ? 98.669  107.755 147.419 1.00 0.05   ? 501 GTP A O1B   1 
HETATM 6586 O O2B   . GTP C 3 .   ? 98.232  105.206 147.774 1.00 0.05   ? 501 GTP A O2B   1 
HETATM 6587 O O3A   . GTP C 3 .   ? 96.409  106.776 147.206 1.00 0.05   ? 501 GTP A O3A   1 
HETATM 6588 P PA    . GTP C 3 .   ? 96.401  106.365 145.680 1.00 0.00   ? 501 GTP A PA    1 
HETATM 6589 O O1A   . GTP C 3 .   ? 97.699  106.800 145.142 1.00 0.00   ? 501 GTP A O1A   1 
HETATM 6590 O O2A   . GTP C 3 .   ? 96.021  104.944 145.695 1.00 0.00   ? 501 GTP A O2A   1 
HETATM 6591 O "O5'" . GTP C 3 .   ? 95.221  107.055 144.907 1.00 0.00   ? 501 GTP A "O5'" 1 
HETATM 6592 C "C5'" . GTP C 3 .   ? 94.172  106.235 144.474 1.00 0.00   ? 501 GTP A "C5'" 1 
HETATM 6593 C "C4'" . GTP C 3 .   ? 93.572  106.820 143.229 1.00 0.00   ? 501 GTP A "C4'" 1 
HETATM 6594 O "O4'" . GTP C 3 .   ? 94.387  106.483 142.136 1.00 0.00   ? 501 GTP A "O4'" 1 
HETATM 6595 C "C3'" . GTP C 3 .   ? 92.264  106.153 142.963 1.00 0.00   ? 501 GTP A "C3'" 1 
HETATM 6596 O "O3'" . GTP C 3 .   ? 91.606  106.765 141.879 1.00 0.00   ? 501 GTP A "O3'" 1 
HETATM 6597 C "C2'" . GTP C 3 .   ? 92.717  104.880 142.413 1.00 0.00   ? 501 GTP A "C2'" 1 
HETATM 6598 O "O2'" . GTP C 3 .   ? 91.703  104.273 141.658 1.00 0.05   ? 501 GTP A "O2'" 1 
HETATM 6599 C "C1'" . GTP C 3 .   ? 93.743  105.404 141.476 1.00 0.00   ? 501 GTP A "C1'" 1 
HETATM 6600 N N9    . GTP C 3 .   ? 94.620  104.263 141.251 1.00 0.05   ? 501 GTP A N9    1 
HETATM 6601 C C8    . GTP C 3 .   ? 95.168  103.502 142.185 1.00 0.05   ? 501 GTP A C8    1 
HETATM 6602 N N7    . GTP C 3 .   ? 95.918  102.531 141.653 1.00 0.05   ? 501 GTP A N7    1 
HETATM 6603 C C5    . GTP C 3 .   ? 95.819  102.688 140.359 1.00 0.05   ? 501 GTP A C5    1 
HETATM 6604 C C6    . GTP C 3 .   ? 96.344  102.003 139.241 1.00 0.05   ? 501 GTP A C6    1 
HETATM 6605 O O6    . GTP C 3 .   ? 97.051  101.040 139.472 1.00 0.05   ? 501 GTP A O6    1 
HETATM 6606 N N1    . GTP C 3 .   ? 96.051  102.425 138.038 1.00 0.05   ? 501 GTP A N1    1 
HETATM 6607 C C2    . GTP C 3 .   ? 95.258  103.465 137.823 1.00 0.05   ? 501 GTP A C2    1 
HETATM 6608 N N2    . GTP C 3 .   ? 94.984  103.853 136.567 1.00 0.05   ? 501 GTP A N2    1 
HETATM 6609 N N3    . GTP C 3 .   ? 94.718  104.150 138.823 1.00 0.05   ? 501 GTP A N3    1 
HETATM 6610 C C4    . GTP C 3 .   ? 94.969  103.804 140.085 1.00 0.05   ? 501 GTP A C4    1 
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