data_9F2V
# 
_entry.id   9F2V 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9F2V         pdb_00009f2v 10.2210/pdb9f2v/pdb 
WWPDB D_1292137978 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-29 
2 'Structure model' 1 1 2025-02-26 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_database_PDB_caveat.id     1 
_database_PDB_caveat.text   'A1H9E A 401 HAS WRONG CHIRALITY AT ATOM C19' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9F2V 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              rolf.hilgenfeld@uni-luebeck.de 
_pdbx_contact_author.name_first         Rolf 
_pdbx_contact_author.name_last          Hilgenfeld 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8850-2977 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'El kilani, H.'  1 0000-0003-4084-3582 
'Hilgenfeld, R.' 2 0000-0001-8850-2977 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            68 
_citation.language                  ? 
_citation.page_first                2920 
_citation.page_last                 2941 
_citation.title                     
'Structure-Based Optimization of Pyridone alpha-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.4c02172 
_citation.pdbx_database_id_PubMed   39817813 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Akula, R.K.'    1  ? 
primary 'El Kilani, H.'  2  ? 
primary 'Metzen, A.'     3  ? 
primary 'Roske, J.'      4  ? 
primary 'Zhang, K.'      5  ? 
primary 'Gohl, M.'       6  ? 
primary 'Arisetti, N.'   7  ? 
primary 'Marsh, G.P.'    8  ? 
primary 'Maple, H.J.'    9  ? 
primary 'Cooper, M.S.'   10 ? 
primary 'Karadogan, B.'  11 ? 
primary 'Jochmans, D.'   12 ? 
primary 'Neyts, J.'      13 ? 
primary 'Rox, K.'        14 ? 
primary 'Hilgenfeld, R.' 15 ? 
primary 'Bronstrup, M.'  16 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '3C-like proteinase nsp5' 33825.547 2   3.4.22.69 ? ? ? 
2 non-polymer syn 
;~{tert}-butyl ~{N}-[1-[(2~{S})-1-[[(2~{R},3~{S})-4-azanyl-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]amino]-3-cyclopropyl-1-oxidanylidene-propan-2-yl]-5-fluoranyl-2-oxidanylidene-pyridin-3-yl]carbamate
;
523.554   2   ?         ? ? ? 
3 water       nat water 18.015    111 ?         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        '3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;~{tert}-butyl ~{N}-[1-[(2~{S})-1-[[(2~{R},3~{S})-4-azanyl-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]amino]-3-cyclopropyl-1-oxidanylidene-propan-2-yl]-5-fluoranyl-2-oxidanylidene-pyridin-3-yl]carbamate
;
A1H9E 
3 water HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   GLY n 
1 3   PHE n 
1 4   ARG n 
1 5   LYS n 
1 6   MET n 
1 7   ALA n 
1 8   PHE n 
1 9   PRO n 
1 10  SER n 
1 11  GLY n 
1 12  LYS n 
1 13  VAL n 
1 14  GLU n 
1 15  GLY n 
1 16  CYS n 
1 17  MET n 
1 18  VAL n 
1 19  GLN n 
1 20  VAL n 
1 21  THR n 
1 22  CYS n 
1 23  GLY n 
1 24  THR n 
1 25  THR n 
1 26  THR n 
1 27  LEU n 
1 28  ASN n 
1 29  GLY n 
1 30  LEU n 
1 31  TRP n 
1 32  LEU n 
1 33  ASP n 
1 34  ASP n 
1 35  VAL n 
1 36  VAL n 
1 37  TYR n 
1 38  CYS n 
1 39  PRO n 
1 40  ARG n 
1 41  HIS n 
1 42  VAL n 
1 43  ILE n 
1 44  CYS n 
1 45  THR n 
1 46  SER n 
1 47  GLU n 
1 48  ASP n 
1 49  MET n 
1 50  LEU n 
1 51  ASN n 
1 52  PRO n 
1 53  ASN n 
1 54  TYR n 
1 55  GLU n 
1 56  ASP n 
1 57  LEU n 
1 58  LEU n 
1 59  ILE n 
1 60  ARG n 
1 61  LYS n 
1 62  SER n 
1 63  ASN n 
1 64  HIS n 
1 65  ASN n 
1 66  PHE n 
1 67  LEU n 
1 68  VAL n 
1 69  GLN n 
1 70  ALA n 
1 71  GLY n 
1 72  ASN n 
1 73  VAL n 
1 74  GLN n 
1 75  LEU n 
1 76  ARG n 
1 77  VAL n 
1 78  ILE n 
1 79  GLY n 
1 80  HIS n 
1 81  SER n 
1 82  MET n 
1 83  GLN n 
1 84  ASN n 
1 85  CYS n 
1 86  VAL n 
1 87  LEU n 
1 88  LYS n 
1 89  LEU n 
1 90  LYS n 
1 91  VAL n 
1 92  ASP n 
1 93  THR n 
1 94  ALA n 
1 95  ASN n 
1 96  PRO n 
1 97  LYS n 
1 98  THR n 
1 99  PRO n 
1 100 LYS n 
1 101 TYR n 
1 102 LYS n 
1 103 PHE n 
1 104 VAL n 
1 105 ARG n 
1 106 ILE n 
1 107 GLN n 
1 108 PRO n 
1 109 GLY n 
1 110 GLN n 
1 111 THR n 
1 112 PHE n 
1 113 SER n 
1 114 VAL n 
1 115 LEU n 
1 116 ALA n 
1 117 CYS n 
1 118 TYR n 
1 119 ASN n 
1 120 GLY n 
1 121 SER n 
1 122 PRO n 
1 123 SER n 
1 124 GLY n 
1 125 VAL n 
1 126 TYR n 
1 127 GLN n 
1 128 CYS n 
1 129 ALA n 
1 130 MET n 
1 131 ARG n 
1 132 PRO n 
1 133 ASN n 
1 134 PHE n 
1 135 THR n 
1 136 ILE n 
1 137 LYS n 
1 138 GLY n 
1 139 SER n 
1 140 PHE n 
1 141 LEU n 
1 142 ASN n 
1 143 GLY n 
1 144 SER n 
1 145 CYS n 
1 146 GLY n 
1 147 SER n 
1 148 VAL n 
1 149 GLY n 
1 150 PHE n 
1 151 ASN n 
1 152 ILE n 
1 153 ASP n 
1 154 TYR n 
1 155 ASP n 
1 156 CYS n 
1 157 VAL n 
1 158 SER n 
1 159 PHE n 
1 160 CYS n 
1 161 TYR n 
1 162 MET n 
1 163 HIS n 
1 164 HIS n 
1 165 MET n 
1 166 GLU n 
1 167 LEU n 
1 168 PRO n 
1 169 THR n 
1 170 GLY n 
1 171 VAL n 
1 172 HIS n 
1 173 ALA n 
1 174 GLY n 
1 175 THR n 
1 176 ASP n 
1 177 LEU n 
1 178 GLU n 
1 179 GLY n 
1 180 ASN n 
1 181 PHE n 
1 182 TYR n 
1 183 GLY n 
1 184 PRO n 
1 185 PHE n 
1 186 VAL n 
1 187 ASP n 
1 188 ARG n 
1 189 GLN n 
1 190 THR n 
1 191 ALA n 
1 192 GLN n 
1 193 ALA n 
1 194 ALA n 
1 195 GLY n 
1 196 THR n 
1 197 ASP n 
1 198 THR n 
1 199 THR n 
1 200 ILE n 
1 201 THR n 
1 202 VAL n 
1 203 ASN n 
1 204 VAL n 
1 205 LEU n 
1 206 ALA n 
1 207 TRP n 
1 208 LEU n 
1 209 TYR n 
1 210 ALA n 
1 211 ALA n 
1 212 VAL n 
1 213 ILE n 
1 214 ASN n 
1 215 GLY n 
1 216 ASP n 
1 217 ARG n 
1 218 TRP n 
1 219 PHE n 
1 220 LEU n 
1 221 ASN n 
1 222 ARG n 
1 223 PHE n 
1 224 THR n 
1 225 THR n 
1 226 THR n 
1 227 LEU n 
1 228 ASN n 
1 229 ASP n 
1 230 PHE n 
1 231 ASN n 
1 232 LEU n 
1 233 VAL n 
1 234 ALA n 
1 235 MET n 
1 236 LYS n 
1 237 TYR n 
1 238 ASN n 
1 239 TYR n 
1 240 GLU n 
1 241 PRO n 
1 242 LEU n 
1 243 THR n 
1 244 GLN n 
1 245 ASP n 
1 246 HIS n 
1 247 VAL n 
1 248 ASP n 
1 249 ILE n 
1 250 LEU n 
1 251 GLY n 
1 252 PRO n 
1 253 LEU n 
1 254 SER n 
1 255 ALA n 
1 256 GLN n 
1 257 THR n 
1 258 GLY n 
1 259 ILE n 
1 260 ALA n 
1 261 VAL n 
1 262 LEU n 
1 263 ASP n 
1 264 MET n 
1 265 CYS n 
1 266 ALA n 
1 267 SER n 
1 268 LEU n 
1 269 LYS n 
1 270 GLU n 
1 271 LEU n 
1 272 LEU n 
1 273 GLN n 
1 274 ASN n 
1 275 GLY n 
1 276 MET n 
1 277 ASN n 
1 278 GLY n 
1 279 ARG n 
1 280 THR n 
1 281 ILE n 
1 282 LEU n 
1 283 GLY n 
1 284 SER n 
1 285 ALA n 
1 286 LEU n 
1 287 LEU n 
1 288 GLU n 
1 289 ASP n 
1 290 GLU n 
1 291 PHE n 
1 292 THR n 
1 293 PRO n 
1 294 PHE n 
1 295 ASP n 
1 296 VAL n 
1 297 VAL n 
1 298 ARG n 
1 299 GLN n 
1 300 CYS n 
1 301 SER n 
1 302 GLY n 
1 303 VAL n 
1 304 THR n 
1 305 PHE n 
1 306 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   306 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'rep, 1a-1b' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Severe acute respiratory syndrome coronavirus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2901879 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli B' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     37762 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1H9E non-polymer         . 
;~{tert}-butyl ~{N}-[1-[(2~{S})-1-[[(2~{R},3~{S})-4-azanyl-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]amino]-3-cyclopropyl-1-oxidanylidene-propan-2-yl]-5-fluoranyl-2-oxidanylidene-pyridin-3-yl]carbamate
;
? 'C24 H34 F N5 O7' 523.554 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'      89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'  175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'     132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'      133.103 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'    121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'    146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'      147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'      75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'  156.162 
HOH   non-polymer         . WATER ? 'H2 O'            18.015  
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'     131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'     131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'  147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'   149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'     165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'      115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'      105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'      119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'   204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'     181.189 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   1   1   SER SER A . n 
A 1 2   GLY 2   2   2   GLY GLY A . n 
A 1 3   PHE 3   3   3   PHE PHE A . n 
A 1 4   ARG 4   4   4   ARG ARG A . n 
A 1 5   LYS 5   5   5   LYS LYS A . n 
A 1 6   MET 6   6   6   MET MET A . n 
A 1 7   ALA 7   7   7   ALA ALA A . n 
A 1 8   PHE 8   8   8   PHE PHE A . n 
A 1 9   PRO 9   9   9   PRO PRO A . n 
A 1 10  SER 10  10  10  SER SER A . n 
A 1 11  GLY 11  11  11  GLY GLY A . n 
A 1 12  LYS 12  12  12  LYS LYS A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  CYS 16  16  16  CYS CYS A . n 
A 1 17  MET 17  17  17  MET MET A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  GLN 19  19  19  GLN GLN A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  THR 21  21  21  THR THR A . n 
A 1 22  CYS 22  22  22  CYS CYS A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  THR 24  24  24  THR THR A . n 
A 1 25  THR 25  25  25  THR THR A . n 
A 1 26  THR 26  26  26  THR THR A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  ASN 28  28  28  ASN ASN A . n 
A 1 29  GLY 29  29  29  GLY GLY A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  TRP 31  31  31  TRP TRP A . n 
A 1 32  LEU 32  32  32  LEU LEU A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  VAL 35  35  35  VAL VAL A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  TYR 37  37  37  TYR TYR A . n 
A 1 38  CYS 38  38  38  CYS CYS A . n 
A 1 39  PRO 39  39  39  PRO PRO A . n 
A 1 40  ARG 40  40  40  ARG ARG A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  ILE 43  43  43  ILE ILE A . n 
A 1 44  CYS 44  44  44  CYS CYS A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  GLU 47  47  47  GLU GLU A . n 
A 1 48  ASP 48  48  48  ASP ASP A . n 
A 1 49  MET 49  49  49  MET MET A . n 
A 1 50  LEU 50  50  50  LEU LEU A . n 
A 1 51  ASN 51  51  51  ASN ASN A . n 
A 1 52  PRO 52  52  52  PRO PRO A . n 
A 1 53  ASN 53  53  53  ASN ASN A . n 
A 1 54  TYR 54  54  54  TYR TYR A . n 
A 1 55  GLU 55  55  55  GLU GLU A . n 
A 1 56  ASP 56  56  56  ASP ASP A . n 
A 1 57  LEU 57  57  57  LEU LEU A . n 
A 1 58  LEU 58  58  58  LEU LEU A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  ARG 60  60  60  ARG ARG A . n 
A 1 61  LYS 61  61  61  LYS LYS A . n 
A 1 62  SER 62  62  62  SER SER A . n 
A 1 63  ASN 63  63  63  ASN ASN A . n 
A 1 64  HIS 64  64  64  HIS HIS A . n 
A 1 65  ASN 65  65  65  ASN ASN A . n 
A 1 66  PHE 66  66  66  PHE PHE A . n 
A 1 67  LEU 67  67  67  LEU LEU A . n 
A 1 68  VAL 68  68  68  VAL VAL A . n 
A 1 69  GLN 69  69  69  GLN GLN A . n 
A 1 70  ALA 70  70  70  ALA ALA A . n 
A 1 71  GLY 71  71  71  GLY GLY A . n 
A 1 72  ASN 72  72  72  ASN ASN A . n 
A 1 73  VAL 73  73  73  VAL VAL A . n 
A 1 74  GLN 74  74  74  GLN GLN A . n 
A 1 75  LEU 75  75  75  LEU LEU A . n 
A 1 76  ARG 76  76  76  ARG ARG A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  ILE 78  78  78  ILE ILE A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  HIS 80  80  80  HIS HIS A . n 
A 1 81  SER 81  81  81  SER SER A . n 
A 1 82  MET 82  82  82  MET MET A . n 
A 1 83  GLN 83  83  83  GLN GLN A . n 
A 1 84  ASN 84  84  84  ASN ASN A . n 
A 1 85  CYS 85  85  85  CYS CYS A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  LYS 88  88  88  LYS LYS A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  LYS 90  90  90  LYS LYS A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  ASP 92  92  92  ASP ASP A . n 
A 1 93  THR 93  93  93  THR THR A . n 
A 1 94  ALA 94  94  94  ALA ALA A . n 
A 1 95  ASN 95  95  95  ASN ASN A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  LYS 97  97  97  LYS LYS A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  PRO 99  99  99  PRO PRO A . n 
A 1 100 LYS 100 100 100 LYS LYS A . n 
A 1 101 TYR 101 101 101 TYR TYR A . n 
A 1 102 LYS 102 102 102 LYS LYS A . n 
A 1 103 PHE 103 103 103 PHE PHE A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 ARG 105 105 105 ARG ARG A . n 
A 1 106 ILE 106 106 106 ILE ILE A . n 
A 1 107 GLN 107 107 107 GLN GLN A . n 
A 1 108 PRO 108 108 108 PRO PRO A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 THR 111 111 111 THR THR A . n 
A 1 112 PHE 112 112 112 PHE PHE A . n 
A 1 113 SER 113 113 113 SER SER A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 ALA 116 116 116 ALA ALA A . n 
A 1 117 CYS 117 117 117 CYS CYS A . n 
A 1 118 TYR 118 118 118 TYR TYR A . n 
A 1 119 ASN 119 119 119 ASN ASN A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 SER 121 121 121 SER SER A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 SER 123 123 123 SER SER A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 TYR 126 126 126 TYR TYR A . n 
A 1 127 GLN 127 127 127 GLN GLN A . n 
A 1 128 CYS 128 128 128 CYS CYS A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 MET 130 130 130 MET MET A . n 
A 1 131 ARG 131 131 131 ARG ARG A . n 
A 1 132 PRO 132 132 132 PRO PRO A . n 
A 1 133 ASN 133 133 133 ASN ASN A . n 
A 1 134 PHE 134 134 134 PHE PHE A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 ILE 136 136 136 ILE ILE A . n 
A 1 137 LYS 137 137 137 LYS LYS A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 PHE 140 140 140 PHE PHE A . n 
A 1 141 LEU 141 141 141 LEU LEU A . n 
A 1 142 ASN 142 142 142 ASN ASN A . n 
A 1 143 GLY 143 143 143 GLY GLY A . n 
A 1 144 SER 144 144 144 SER SER A . n 
A 1 145 CYS 145 145 145 CYS CYS A . n 
A 1 146 GLY 146 146 146 GLY GLY A . n 
A 1 147 SER 147 147 147 SER SER A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 GLY 149 149 149 GLY GLY A . n 
A 1 150 PHE 150 150 150 PHE PHE A . n 
A 1 151 ASN 151 151 151 ASN ASN A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 ASP 153 153 153 ASP ASP A . n 
A 1 154 TYR 154 154 154 TYR TYR A . n 
A 1 155 ASP 155 155 155 ASP ASP A . n 
A 1 156 CYS 156 156 156 CYS CYS A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 SER 158 158 158 SER SER A . n 
A 1 159 PHE 159 159 159 PHE PHE A . n 
A 1 160 CYS 160 160 160 CYS CYS A . n 
A 1 161 TYR 161 161 161 TYR TYR A . n 
A 1 162 MET 162 162 162 MET MET A . n 
A 1 163 HIS 163 163 163 HIS HIS A . n 
A 1 164 HIS 164 164 164 HIS HIS A . n 
A 1 165 MET 165 165 165 MET MET A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 PRO 168 168 168 PRO PRO A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 GLY 170 170 170 GLY GLY A . n 
A 1 171 VAL 171 171 171 VAL VAL A . n 
A 1 172 HIS 172 172 172 HIS HIS A . n 
A 1 173 ALA 173 173 173 ALA ALA A . n 
A 1 174 GLY 174 174 174 GLY GLY A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 ASP 176 176 176 ASP ASP A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 GLU 178 178 178 GLU GLU A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 ASN 180 180 180 ASN ASN A . n 
A 1 181 PHE 181 181 181 PHE PHE A . n 
A 1 182 TYR 182 182 182 TYR TYR A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 PRO 184 184 184 PRO PRO A . n 
A 1 185 PHE 185 185 185 PHE PHE A . n 
A 1 186 VAL 186 186 186 VAL VAL A . n 
A 1 187 ASP 187 187 187 ASP ASP A . n 
A 1 188 ARG 188 188 188 ARG ARG A . n 
A 1 189 GLN 189 189 189 GLN GLN A . n 
A 1 190 THR 190 190 190 THR THR A . n 
A 1 191 ALA 191 191 191 ALA ALA A . n 
A 1 192 GLN 192 192 192 GLN GLN A . n 
A 1 193 ALA 193 193 193 ALA ALA A . n 
A 1 194 ALA 194 194 194 ALA ALA A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 THR 196 196 196 THR THR A . n 
A 1 197 ASP 197 197 197 ASP ASP A . n 
A 1 198 THR 198 198 198 THR THR A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 ILE 200 200 200 ILE ILE A . n 
A 1 201 THR 201 201 201 THR THR A . n 
A 1 202 VAL 202 202 202 VAL VAL A . n 
A 1 203 ASN 203 203 203 ASN ASN A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 ALA 206 206 206 ALA ALA A . n 
A 1 207 TRP 207 207 207 TRP TRP A . n 
A 1 208 LEU 208 208 208 LEU LEU A . n 
A 1 209 TYR 209 209 209 TYR TYR A . n 
A 1 210 ALA 210 210 210 ALA ALA A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 ILE 213 213 213 ILE ILE A . n 
A 1 214 ASN 214 214 214 ASN ASN A . n 
A 1 215 GLY 215 215 215 GLY GLY A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 ARG 217 217 217 ARG ARG A . n 
A 1 218 TRP 218 218 218 TRP TRP A . n 
A 1 219 PHE 219 219 219 PHE PHE A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 ASN 221 221 221 ASN ASN A . n 
A 1 222 ARG 222 222 222 ARG ARG A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 THR 224 224 224 THR THR A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 ASN 228 228 228 ASN ASN A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 PHE 230 230 230 PHE PHE A . n 
A 1 231 ASN 231 231 231 ASN ASN A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 MET 235 235 235 MET MET A . n 
A 1 236 LYS 236 236 236 LYS LYS A . n 
A 1 237 TYR 237 237 237 TYR TYR A . n 
A 1 238 ASN 238 238 238 ASN ASN A . n 
A 1 239 TYR 239 239 239 TYR TYR A . n 
A 1 240 GLU 240 240 240 GLU GLU A . n 
A 1 241 PRO 241 241 241 PRO PRO A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 THR 243 243 243 THR THR A . n 
A 1 244 GLN 244 244 244 GLN GLN A . n 
A 1 245 ASP 245 245 245 ASP ASP A . n 
A 1 246 HIS 246 246 246 HIS HIS A . n 
A 1 247 VAL 247 247 247 VAL VAL A . n 
A 1 248 ASP 248 248 248 ASP ASP A . n 
A 1 249 ILE 249 249 249 ILE ILE A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 PRO 252 252 252 PRO PRO A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 GLN 256 256 256 GLN GLN A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLY 258 258 258 GLY GLY A . n 
A 1 259 ILE 259 259 259 ILE ILE A . n 
A 1 260 ALA 260 260 260 ALA ALA A . n 
A 1 261 VAL 261 261 261 VAL VAL A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 ASP 263 263 263 ASP ASP A . n 
A 1 264 MET 264 264 264 MET MET A . n 
A 1 265 CYS 265 265 265 CYS CYS A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 SER 267 267 267 SER SER A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 LYS 269 269 269 LYS LYS A . n 
A 1 270 GLU 270 270 270 GLU GLU A . n 
A 1 271 LEU 271 271 271 LEU LEU A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 GLN 273 273 273 GLN GLN A . n 
A 1 274 ASN 274 274 274 ASN ASN A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 MET 276 276 276 MET MET A . n 
A 1 277 ASN 277 277 277 ASN ASN A . n 
A 1 278 GLY 278 278 278 GLY GLY A . n 
A 1 279 ARG 279 279 279 ARG ARG A . n 
A 1 280 THR 280 280 280 THR THR A . n 
A 1 281 ILE 281 281 281 ILE ILE A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 GLY 283 283 283 GLY GLY A . n 
A 1 284 SER 284 284 284 SER SER A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 LEU 286 286 286 LEU LEU A . n 
A 1 287 LEU 287 287 287 LEU LEU A . n 
A 1 288 GLU 288 288 288 GLU GLU A . n 
A 1 289 ASP 289 289 289 ASP ASP A . n 
A 1 290 GLU 290 290 290 GLU GLU A . n 
A 1 291 PHE 291 291 291 PHE PHE A . n 
A 1 292 THR 292 292 292 THR THR A . n 
A 1 293 PRO 293 293 293 PRO PRO A . n 
A 1 294 PHE 294 294 294 PHE PHE A . n 
A 1 295 ASP 295 295 295 ASP ASP A . n 
A 1 296 VAL 296 296 296 VAL VAL A . n 
A 1 297 VAL 297 297 297 VAL VAL A . n 
A 1 298 ARG 298 298 298 ARG ARG A . n 
A 1 299 GLN 299 299 299 GLN GLN A . n 
A 1 300 CYS 300 300 300 CYS CYS A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 GLY 302 302 302 GLY GLY A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 THR 304 304 304 THR THR A . n 
A 1 305 PHE 305 305 305 PHE PHE A . n 
A 1 306 GLN 306 306 306 GLN GLN A . n 
B 1 1   SER 1   1   1   SER SER B . n 
B 1 2   GLY 2   2   2   GLY GLY B . n 
B 1 3   PHE 3   3   3   PHE PHE B . n 
B 1 4   ARG 4   4   4   ARG ARG B . n 
B 1 5   LYS 5   5   5   LYS LYS B . n 
B 1 6   MET 6   6   6   MET MET B . n 
B 1 7   ALA 7   7   7   ALA ALA B . n 
B 1 8   PHE 8   8   8   PHE PHE B . n 
B 1 9   PRO 9   9   9   PRO PRO B . n 
B 1 10  SER 10  10  10  SER SER B . n 
B 1 11  GLY 11  11  11  GLY GLY B . n 
B 1 12  LYS 12  12  12  LYS LYS B . n 
B 1 13  VAL 13  13  13  VAL VAL B . n 
B 1 14  GLU 14  14  14  GLU GLU B . n 
B 1 15  GLY 15  15  15  GLY GLY B . n 
B 1 16  CYS 16  16  16  CYS CYS B . n 
B 1 17  MET 17  17  17  MET MET B . n 
B 1 18  VAL 18  18  18  VAL VAL B . n 
B 1 19  GLN 19  19  19  GLN GLN B . n 
B 1 20  VAL 20  20  20  VAL VAL B . n 
B 1 21  THR 21  21  21  THR THR B . n 
B 1 22  CYS 22  22  22  CYS CYS B . n 
B 1 23  GLY 23  23  23  GLY GLY B . n 
B 1 24  THR 24  24  24  THR THR B . n 
B 1 25  THR 25  25  25  THR THR B . n 
B 1 26  THR 26  26  26  THR THR B . n 
B 1 27  LEU 27  27  27  LEU LEU B . n 
B 1 28  ASN 28  28  28  ASN ASN B . n 
B 1 29  GLY 29  29  29  GLY GLY B . n 
B 1 30  LEU 30  30  30  LEU LEU B . n 
B 1 31  TRP 31  31  31  TRP TRP B . n 
B 1 32  LEU 32  32  32  LEU LEU B . n 
B 1 33  ASP 33  33  33  ASP ASP B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  VAL 35  35  35  VAL VAL B . n 
B 1 36  VAL 36  36  36  VAL VAL B . n 
B 1 37  TYR 37  37  37  TYR TYR B . n 
B 1 38  CYS 38  38  38  CYS CYS B . n 
B 1 39  PRO 39  39  39  PRO PRO B . n 
B 1 40  ARG 40  40  40  ARG ARG B . n 
B 1 41  HIS 41  41  41  HIS HIS B . n 
B 1 42  VAL 42  42  42  VAL VAL B . n 
B 1 43  ILE 43  43  43  ILE ILE B . n 
B 1 44  CYS 44  44  44  CYS CYS B . n 
B 1 45  THR 45  45  45  THR THR B . n 
B 1 46  SER 46  46  46  SER SER B . n 
B 1 47  GLU 47  47  47  GLU GLU B . n 
B 1 48  ASP 48  48  48  ASP ASP B . n 
B 1 49  MET 49  49  49  MET MET B . n 
B 1 50  LEU 50  50  50  LEU LEU B . n 
B 1 51  ASN 51  51  51  ASN ASN B . n 
B 1 52  PRO 52  52  52  PRO PRO B . n 
B 1 53  ASN 53  53  53  ASN ASN B . n 
B 1 54  TYR 54  54  54  TYR TYR B . n 
B 1 55  GLU 55  55  55  GLU GLU B . n 
B 1 56  ASP 56  56  56  ASP ASP B . n 
B 1 57  LEU 57  57  57  LEU LEU B . n 
B 1 58  LEU 58  58  58  LEU LEU B . n 
B 1 59  ILE 59  59  59  ILE ILE B . n 
B 1 60  ARG 60  60  60  ARG ARG B . n 
B 1 61  LYS 61  61  61  LYS LYS B . n 
B 1 62  SER 62  62  62  SER SER B . n 
B 1 63  ASN 63  63  63  ASN ASN B . n 
B 1 64  HIS 64  64  64  HIS HIS B . n 
B 1 65  ASN 65  65  65  ASN ASN B . n 
B 1 66  PHE 66  66  66  PHE PHE B . n 
B 1 67  LEU 67  67  67  LEU LEU B . n 
B 1 68  VAL 68  68  68  VAL VAL B . n 
B 1 69  GLN 69  69  69  GLN GLN B . n 
B 1 70  ALA 70  70  70  ALA ALA B . n 
B 1 71  GLY 71  71  71  GLY GLY B . n 
B 1 72  ASN 72  72  72  ASN ASN B . n 
B 1 73  VAL 73  73  73  VAL VAL B . n 
B 1 74  GLN 74  74  74  GLN GLN B . n 
B 1 75  LEU 75  75  75  LEU LEU B . n 
B 1 76  ARG 76  76  76  ARG ARG B . n 
B 1 77  VAL 77  77  77  VAL VAL B . n 
B 1 78  ILE 78  78  78  ILE ILE B . n 
B 1 79  GLY 79  79  79  GLY GLY B . n 
B 1 80  HIS 80  80  80  HIS HIS B . n 
B 1 81  SER 81  81  81  SER SER B . n 
B 1 82  MET 82  82  82  MET MET B . n 
B 1 83  GLN 83  83  83  GLN GLN B . n 
B 1 84  ASN 84  84  84  ASN ASN B . n 
B 1 85  CYS 85  85  85  CYS CYS B . n 
B 1 86  VAL 86  86  86  VAL VAL B . n 
B 1 87  LEU 87  87  87  LEU LEU B . n 
B 1 88  LYS 88  88  88  LYS LYS B . n 
B 1 89  LEU 89  89  89  LEU LEU B . n 
B 1 90  LYS 90  90  90  LYS LYS B . n 
B 1 91  VAL 91  91  91  VAL VAL B . n 
B 1 92  ASP 92  92  92  ASP ASP B . n 
B 1 93  THR 93  93  93  THR THR B . n 
B 1 94  ALA 94  94  94  ALA ALA B . n 
B 1 95  ASN 95  95  95  ASN ASN B . n 
B 1 96  PRO 96  96  96  PRO PRO B . n 
B 1 97  LYS 97  97  97  LYS LYS B . n 
B 1 98  THR 98  98  98  THR THR B . n 
B 1 99  PRO 99  99  99  PRO PRO B . n 
B 1 100 LYS 100 100 100 LYS LYS B . n 
B 1 101 TYR 101 101 101 TYR TYR B . n 
B 1 102 LYS 102 102 102 LYS LYS B . n 
B 1 103 PHE 103 103 103 PHE PHE B . n 
B 1 104 VAL 104 104 104 VAL VAL B . n 
B 1 105 ARG 105 105 105 ARG ARG B . n 
B 1 106 ILE 106 106 106 ILE ILE B . n 
B 1 107 GLN 107 107 107 GLN GLN B . n 
B 1 108 PRO 108 108 108 PRO PRO B . n 
B 1 109 GLY 109 109 109 GLY GLY B . n 
B 1 110 GLN 110 110 110 GLN GLN B . n 
B 1 111 THR 111 111 111 THR THR B . n 
B 1 112 PHE 112 112 112 PHE PHE B . n 
B 1 113 SER 113 113 113 SER SER B . n 
B 1 114 VAL 114 114 114 VAL VAL B . n 
B 1 115 LEU 115 115 115 LEU LEU B . n 
B 1 116 ALA 116 116 116 ALA ALA B . n 
B 1 117 CYS 117 117 117 CYS CYS B . n 
B 1 118 TYR 118 118 118 TYR TYR B . n 
B 1 119 ASN 119 119 119 ASN ASN B . n 
B 1 120 GLY 120 120 120 GLY GLY B . n 
B 1 121 SER 121 121 121 SER SER B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 SER 123 123 123 SER SER B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 TYR 126 126 126 TYR TYR B . n 
B 1 127 GLN 127 127 127 GLN GLN B . n 
B 1 128 CYS 128 128 128 CYS CYS B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 MET 130 130 130 MET MET B . n 
B 1 131 ARG 131 131 131 ARG ARG B . n 
B 1 132 PRO 132 132 132 PRO PRO B . n 
B 1 133 ASN 133 133 133 ASN ASN B . n 
B 1 134 PHE 134 134 134 PHE PHE B . n 
B 1 135 THR 135 135 135 THR THR B . n 
B 1 136 ILE 136 136 136 ILE ILE B . n 
B 1 137 LYS 137 137 137 LYS LYS B . n 
B 1 138 GLY 138 138 138 GLY GLY B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 PHE 140 140 140 PHE PHE B . n 
B 1 141 LEU 141 141 141 LEU LEU B . n 
B 1 142 ASN 142 142 142 ASN ASN B . n 
B 1 143 GLY 143 143 143 GLY GLY B . n 
B 1 144 SER 144 144 144 SER SER B . n 
B 1 145 CYS 145 145 145 CYS CYS B . n 
B 1 146 GLY 146 146 146 GLY GLY B . n 
B 1 147 SER 147 147 147 SER SER B . n 
B 1 148 VAL 148 148 148 VAL VAL B . n 
B 1 149 GLY 149 149 149 GLY GLY B . n 
B 1 150 PHE 150 150 150 PHE PHE B . n 
B 1 151 ASN 151 151 151 ASN ASN B . n 
B 1 152 ILE 152 152 152 ILE ILE B . n 
B 1 153 ASP 153 153 153 ASP ASP B . n 
B 1 154 TYR 154 154 154 TYR TYR B . n 
B 1 155 ASP 155 155 155 ASP ASP B . n 
B 1 156 CYS 156 156 156 CYS CYS B . n 
B 1 157 VAL 157 157 157 VAL VAL B . n 
B 1 158 SER 158 158 158 SER SER B . n 
B 1 159 PHE 159 159 159 PHE PHE B . n 
B 1 160 CYS 160 160 160 CYS CYS B . n 
B 1 161 TYR 161 161 161 TYR TYR B . n 
B 1 162 MET 162 162 162 MET MET B . n 
B 1 163 HIS 163 163 163 HIS HIS B . n 
B 1 164 HIS 164 164 164 HIS HIS B . n 
B 1 165 MET 165 165 165 MET MET B . n 
B 1 166 GLU 166 166 166 GLU GLU B . n 
B 1 167 LEU 167 167 167 LEU LEU B . n 
B 1 168 PRO 168 168 168 PRO PRO B . n 
B 1 169 THR 169 169 169 THR THR B . n 
B 1 170 GLY 170 170 170 GLY GLY B . n 
B 1 171 VAL 171 171 171 VAL VAL B . n 
B 1 172 HIS 172 172 172 HIS HIS B . n 
B 1 173 ALA 173 173 173 ALA ALA B . n 
B 1 174 GLY 174 174 174 GLY GLY B . n 
B 1 175 THR 175 175 175 THR THR B . n 
B 1 176 ASP 176 176 176 ASP ASP B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 GLU 178 178 178 GLU GLU B . n 
B 1 179 GLY 179 179 179 GLY GLY B . n 
B 1 180 ASN 180 180 180 ASN ASN B . n 
B 1 181 PHE 181 181 181 PHE PHE B . n 
B 1 182 TYR 182 182 182 TYR TYR B . n 
B 1 183 GLY 183 183 183 GLY GLY B . n 
B 1 184 PRO 184 184 184 PRO PRO B . n 
B 1 185 PHE 185 185 185 PHE PHE B . n 
B 1 186 VAL 186 186 186 VAL VAL B . n 
B 1 187 ASP 187 187 187 ASP ASP B . n 
B 1 188 ARG 188 188 188 ARG ARG B . n 
B 1 189 GLN 189 189 189 GLN GLN B . n 
B 1 190 THR 190 190 190 THR THR B . n 
B 1 191 ALA 191 191 191 ALA ALA B . n 
B 1 192 GLN 192 192 192 GLN GLN B . n 
B 1 193 ALA 193 193 193 ALA ALA B . n 
B 1 194 ALA 194 194 194 ALA ALA B . n 
B 1 195 GLY 195 195 195 GLY GLY B . n 
B 1 196 THR 196 196 196 THR THR B . n 
B 1 197 ASP 197 197 197 ASP ASP B . n 
B 1 198 THR 198 198 198 THR THR B . n 
B 1 199 THR 199 199 199 THR THR B . n 
B 1 200 ILE 200 200 200 ILE ILE B . n 
B 1 201 THR 201 201 201 THR THR B . n 
B 1 202 VAL 202 202 202 VAL VAL B . n 
B 1 203 ASN 203 203 203 ASN ASN B . n 
B 1 204 VAL 204 204 204 VAL VAL B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 ALA 206 206 206 ALA ALA B . n 
B 1 207 TRP 207 207 207 TRP TRP B . n 
B 1 208 LEU 208 208 208 LEU LEU B . n 
B 1 209 TYR 209 209 209 TYR TYR B . n 
B 1 210 ALA 210 210 210 ALA ALA B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 VAL 212 212 212 VAL VAL B . n 
B 1 213 ILE 213 213 213 ILE ILE B . n 
B 1 214 ASN 214 214 214 ASN ASN B . n 
B 1 215 GLY 215 215 215 GLY GLY B . n 
B 1 216 ASP 216 216 216 ASP ASP B . n 
B 1 217 ARG 217 217 217 ARG ARG B . n 
B 1 218 TRP 218 218 218 TRP TRP B . n 
B 1 219 PHE 219 219 219 PHE PHE B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 ASN 221 221 221 ASN ASN B . n 
B 1 222 ARG 222 222 222 ARG ARG B . n 
B 1 223 PHE 223 223 223 PHE PHE B . n 
B 1 224 THR 224 224 224 THR THR B . n 
B 1 225 THR 225 225 225 THR THR B . n 
B 1 226 THR 226 226 226 THR THR B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 ASN 228 228 228 ASN ASN B . n 
B 1 229 ASP 229 229 229 ASP ASP B . n 
B 1 230 PHE 230 230 230 PHE PHE B . n 
B 1 231 ASN 231 231 231 ASN ASN B . n 
B 1 232 LEU 232 232 232 LEU LEU B . n 
B 1 233 VAL 233 233 233 VAL VAL B . n 
B 1 234 ALA 234 234 234 ALA ALA B . n 
B 1 235 MET 235 235 235 MET MET B . n 
B 1 236 LYS 236 236 236 LYS LYS B . n 
B 1 237 TYR 237 237 237 TYR TYR B . n 
B 1 238 ASN 238 238 238 ASN ASN B . n 
B 1 239 TYR 239 239 239 TYR TYR B . n 
B 1 240 GLU 240 240 240 GLU GLU B . n 
B 1 241 PRO 241 241 241 PRO PRO B . n 
B 1 242 LEU 242 242 242 LEU LEU B . n 
B 1 243 THR 243 243 243 THR THR B . n 
B 1 244 GLN 244 244 244 GLN GLN B . n 
B 1 245 ASP 245 245 245 ASP ASP B . n 
B 1 246 HIS 246 246 246 HIS HIS B . n 
B 1 247 VAL 247 247 247 VAL VAL B . n 
B 1 248 ASP 248 248 248 ASP ASP B . n 
B 1 249 ILE 249 249 249 ILE ILE B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 GLY 251 251 251 GLY GLY B . n 
B 1 252 PRO 252 252 252 PRO PRO B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 SER 254 254 254 SER SER B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 GLN 256 256 256 GLN GLN B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLY 258 258 258 GLY GLY B . n 
B 1 259 ILE 259 259 259 ILE ILE B . n 
B 1 260 ALA 260 260 260 ALA ALA B . n 
B 1 261 VAL 261 261 261 VAL VAL B . n 
B 1 262 LEU 262 262 262 LEU LEU B . n 
B 1 263 ASP 263 263 263 ASP ASP B . n 
B 1 264 MET 264 264 264 MET MET B . n 
B 1 265 CYS 265 265 265 CYS CYS B . n 
B 1 266 ALA 266 266 266 ALA ALA B . n 
B 1 267 SER 267 267 267 SER SER B . n 
B 1 268 LEU 268 268 268 LEU LEU B . n 
B 1 269 LYS 269 269 269 LYS LYS B . n 
B 1 270 GLU 270 270 270 GLU GLU B . n 
B 1 271 LEU 271 271 271 LEU LEU B . n 
B 1 272 LEU 272 272 272 LEU LEU B . n 
B 1 273 GLN 273 273 273 GLN GLN B . n 
B 1 274 ASN 274 274 274 ASN ASN B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 MET 276 276 276 MET MET B . n 
B 1 277 ASN 277 277 277 ASN ASN B . n 
B 1 278 GLY 278 278 278 GLY GLY B . n 
B 1 279 ARG 279 279 279 ARG ARG B . n 
B 1 280 THR 280 280 280 THR THR B . n 
B 1 281 ILE 281 281 281 ILE ILE B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 GLY 283 283 283 GLY GLY B . n 
B 1 284 SER 284 284 284 SER SER B . n 
B 1 285 ALA 285 285 285 ALA ALA B . n 
B 1 286 LEU 286 286 286 LEU LEU B . n 
B 1 287 LEU 287 287 287 LEU LEU B . n 
B 1 288 GLU 288 288 288 GLU GLU B . n 
B 1 289 ASP 289 289 289 ASP ASP B . n 
B 1 290 GLU 290 290 290 GLU GLU B . n 
B 1 291 PHE 291 291 291 PHE PHE B . n 
B 1 292 THR 292 292 292 THR THR B . n 
B 1 293 PRO 293 293 293 PRO PRO B . n 
B 1 294 PHE 294 294 294 PHE PHE B . n 
B 1 295 ASP 295 295 295 ASP ASP B . n 
B 1 296 VAL 296 296 296 VAL VAL B . n 
B 1 297 VAL 297 297 297 VAL VAL B . n 
B 1 298 ARG 298 298 298 ARG ARG B . n 
B 1 299 GLN 299 299 299 GLN GLN B . n 
B 1 300 CYS 300 300 300 CYS CYS B . n 
B 1 301 SER 301 301 301 SER SER B . n 
B 1 302 GLY 302 302 302 GLY GLY B . n 
B 1 303 VAL 303 303 303 VAL VAL B . n 
B 1 304 THR 304 304 304 THR THR B . n 
B 1 305 PHE 305 305 ?   ?   ?   B . n 
B 1 306 GLN 306 306 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1H9E 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1H9E 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 A1H9E 1  401 401 A1H9E LIG A . 
D 2 A1H9E 1  401 401 A1H9E LIG B . 
E 3 HOH   1  501 131 HOH   HOH A . 
E 3 HOH   2  502 93  HOH   HOH A . 
E 3 HOH   3  503 100 HOH   HOH A . 
E 3 HOH   4  504 121 HOH   HOH A . 
E 3 HOH   5  505 94  HOH   HOH A . 
E 3 HOH   6  506 18  HOH   HOH A . 
E 3 HOH   7  507 124 HOH   HOH A . 
E 3 HOH   8  508 95  HOH   HOH A . 
E 3 HOH   9  509 25  HOH   HOH A . 
E 3 HOH   10 510 45  HOH   HOH A . 
E 3 HOH   11 511 130 HOH   HOH A . 
E 3 HOH   12 512 28  HOH   HOH A . 
E 3 HOH   13 513 38  HOH   HOH A . 
E 3 HOH   14 514 57  HOH   HOH A . 
E 3 HOH   15 515 102 HOH   HOH A . 
E 3 HOH   16 516 123 HOH   HOH A . 
E 3 HOH   17 517 47  HOH   HOH A . 
E 3 HOH   18 518 40  HOH   HOH A . 
E 3 HOH   19 519 106 HOH   HOH A . 
E 3 HOH   20 520 101 HOH   HOH A . 
E 3 HOH   21 521 27  HOH   HOH A . 
E 3 HOH   22 522 98  HOH   HOH A . 
E 3 HOH   23 523 14  HOH   HOH A . 
E 3 HOH   24 524 129 HOH   HOH A . 
E 3 HOH   25 525 122 HOH   HOH A . 
E 3 HOH   26 526 79  HOH   HOH A . 
E 3 HOH   27 527 22  HOH   HOH A . 
E 3 HOH   28 528 68  HOH   HOH A . 
E 3 HOH   29 529 36  HOH   HOH A . 
E 3 HOH   30 530 107 HOH   HOH A . 
E 3 HOH   31 531 53  HOH   HOH A . 
E 3 HOH   32 532 128 HOH   HOH A . 
E 3 HOH   33 533 126 HOH   HOH A . 
E 3 HOH   34 534 96  HOH   HOH A . 
E 3 HOH   35 535 125 HOH   HOH A . 
E 3 HOH   36 536 75  HOH   HOH A . 
E 3 HOH   37 537 77  HOH   HOH A . 
E 3 HOH   38 538 103 HOH   HOH A . 
E 3 HOH   39 539 17  HOH   HOH A . 
E 3 HOH   40 540 30  HOH   HOH A . 
E 3 HOH   41 541 51  HOH   HOH A . 
E 3 HOH   42 542 69  HOH   HOH A . 
E 3 HOH   43 543 99  HOH   HOH A . 
E 3 HOH   44 544 2   HOH   HOH A . 
E 3 HOH   45 545 86  HOH   HOH A . 
E 3 HOH   46 546 105 HOH   HOH A . 
E 3 HOH   47 547 62  HOH   HOH A . 
E 3 HOH   48 548 127 HOH   HOH A . 
E 3 HOH   49 549 20  HOH   HOH A . 
E 3 HOH   50 550 92  HOH   HOH A . 
E 3 HOH   51 551 16  HOH   HOH A . 
E 3 HOH   52 552 19  HOH   HOH A . 
E 3 HOH   53 553 97  HOH   HOH A . 
E 3 HOH   54 554 37  HOH   HOH A . 
E 3 HOH   55 555 23  HOH   HOH A . 
E 3 HOH   56 556 70  HOH   HOH A . 
E 3 HOH   57 557 87  HOH   HOH A . 
E 3 HOH   58 558 50  HOH   HOH A . 
E 3 HOH   59 559 31  HOH   HOH A . 
E 3 HOH   60 560 13  HOH   HOH A . 
E 3 HOH   61 561 39  HOH   HOH A . 
E 3 HOH   62 562 66  HOH   HOH A . 
E 3 HOH   63 563 104 HOH   HOH A . 
E 3 HOH   64 564 108 HOH   HOH A . 
F 3 HOH   1  501 60  HOH   HOH B . 
F 3 HOH   2  502 35  HOH   HOH B . 
F 3 HOH   3  503 3   HOH   HOH B . 
F 3 HOH   4  504 116 HOH   HOH B . 
F 3 HOH   5  505 118 HOH   HOH B . 
F 3 HOH   6  506 26  HOH   HOH B . 
F 3 HOH   7  507 119 HOH   HOH B . 
F 3 HOH   8  508 34  HOH   HOH B . 
F 3 HOH   9  509 43  HOH   HOH B . 
F 3 HOH   10 510 120 HOH   HOH B . 
F 3 HOH   11 511 112 HOH   HOH B . 
F 3 HOH   12 512 111 HOH   HOH B . 
F 3 HOH   13 513 83  HOH   HOH B . 
F 3 HOH   14 514 81  HOH   HOH B . 
F 3 HOH   15 515 42  HOH   HOH B . 
F 3 HOH   16 516 10  HOH   HOH B . 
F 3 HOH   17 517 63  HOH   HOH B . 
F 3 HOH   18 518 44  HOH   HOH B . 
F 3 HOH   19 519 24  HOH   HOH B . 
F 3 HOH   20 520 113 HOH   HOH B . 
F 3 HOH   21 521 52  HOH   HOH B . 
F 3 HOH   22 522 114 HOH   HOH B . 
F 3 HOH   23 523 117 HOH   HOH B . 
F 3 HOH   24 524 58  HOH   HOH B . 
F 3 HOH   25 525 110 HOH   HOH B . 
F 3 HOH   26 526 54  HOH   HOH B . 
F 3 HOH   27 527 48  HOH   HOH B . 
F 3 HOH   28 528 1   HOH   HOH B . 
F 3 HOH   29 529 55  HOH   HOH B . 
F 3 HOH   30 530 29  HOH   HOH B . 
F 3 HOH   31 531 65  HOH   HOH B . 
F 3 HOH   32 532 4   HOH   HOH B . 
F 3 HOH   33 533 5   HOH   HOH B . 
F 3 HOH   34 534 80  HOH   HOH B . 
F 3 HOH   35 535 89  HOH   HOH B . 
F 3 HOH   36 536 82  HOH   HOH B . 
F 3 HOH   37 537 109 HOH   HOH B . 
F 3 HOH   38 538 59  HOH   HOH B . 
F 3 HOH   39 539 78  HOH   HOH B . 
F 3 HOH   40 540 115 HOH   HOH B . 
F 3 HOH   41 541 11  HOH   HOH B . 
F 3 HOH   42 542 91  HOH   HOH B . 
F 3 HOH   43 543 71  HOH   HOH B . 
F 3 HOH   44 544 85  HOH   HOH B . 
F 3 HOH   45 545 67  HOH   HOH B . 
F 3 HOH   46 546 90  HOH   HOH B . 
F 3 HOH   47 547 64  HOH   HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0419 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP  ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   91.171 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9F2V 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     45.852 
_cell.length_a_esd                 ? 
_cell.length_b                     63.688 
_cell.length_b_esd                 ? 
_cell.length_c                     103.506 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9F2V 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9F2V 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.26 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          45.52 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.50 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1M Bis Tris Propane pH 7.50, 2M Sodium nitrate, 20% w/vPEG 3350 and 10% v/vEthylene glycol' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-11-24 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.0332 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, DESY BEAMLINE P11' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.0332 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   P11 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, DESY' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9F2V 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.191 
_reflns.d_resolution_low                               45.884 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     208789 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.79 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          19.90 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.08664 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.191 
_reflns_shell.d_res_low                                     2.27 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2890 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.973 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -1.203 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.394 
_refine.aniso_B[2][2]                            0.634 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            0.552 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               23.194 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.953 
_refine.correlation_coeff_Fo_to_Fc_free          0.934 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9F2V 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.191 
_refine.ls_d_res_low                             45.884 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     30460 
_refine.ls_number_reflns_R_free                  1498 
_refine.ls_number_reflns_R_work                  28962 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.768 
_refine.ls_percent_reflns_R_free                 4.918 
_refine.ls_R_factor_all                          0.169 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2091 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1667 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.270 
_refine.pdbx_overall_ESU_R_Free                  0.192 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             4.816 
_refine.overall_SU_ML                            0.125 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.191 
_refine_hist.d_res_low                        45.884 
_refine_hist.number_atoms_solvent             111 
_refine_hist.number_atoms_total               4899 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4714 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         74 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  4899  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  4533  ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.634  1.675  6664  ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.723  1.590  10412 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 7.474  5.000  608   ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 8.006  5.000  22    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.412 10.000 773   ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 6.765  10.000 2     ? r_dihedral_angle_other_3_deg   ? ? 
'X-RAY DIFFRACTION' ? 16.329 10.000 218   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.154  0.200  752   ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  5793  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  1159  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.208  0.200  858   ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.198  0.200  4276  ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.183  0.200  2450  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.087  0.200  2611  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.119  0.200  140   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.268  0.200  5     ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.197  0.200  35    ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.088  0.200  2     ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 1.985  2.163  2438  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 1.983  2.164  2438  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 3.080  3.871  3044  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.080  3.873  3045  ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 2.900  2.523  2461  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.899  2.523  2462  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 4.656  4.471  3614  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.655  4.471  3615  ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 6.304  20.425 5197  ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.303  20.422 5192  ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.191 2.248  2236 . 111 1986 93.7835  . 0.188 . . 0.185 . . . . . 0.170 . 20 . 0.979 0.965 0.237 
'X-RAY DIFFRACTION' 2.248 2.309  2212 . 118 2090 99.8192  . 0.181 . . 0.177 . . . . . 0.170 . 20 . 0.982 0.959 0.259 
'X-RAY DIFFRACTION' 2.309 2.376  2149 . 97  2047 99.7673  . 0.177 . . 0.174 . . . . . 0.168 . 20 . 0.982 0.966 0.229 
'X-RAY DIFFRACTION' 2.376 2.449  2077 . 89  1977 99.4704  . 0.171 . . 0.168 . . . . . 0.163 . 20 . 0.984 0.961 0.237 
'X-RAY DIFFRACTION' 2.449 2.529  2042 . 92  1941 99.5592  . 0.165 . . 0.162 . . . . . 0.158 . 20 . 0.984 0.973 0.223 
'X-RAY DIFFRACTION' 2.529 2.618  1927 . 93  1814 98.9621  . 0.154 . . 0.152 . . . . . 0.149 . 20 . 0.986 0.972 0.210 
'X-RAY DIFFRACTION' 2.618 2.716  1904 . 109 1752 97.7416  . 0.177 . . 0.173 . . . . . 0.170 . 20 . 0.982 0.966 0.236 
'X-RAY DIFFRACTION' 2.716 2.827  1788 . 103 1683 99.8881  . 0.181 . . 0.177 . . . . . 0.180 . 20 . 0.981 0.960 0.234 
'X-RAY DIFFRACTION' 2.827 2.952  1759 . 69  1683 99.6021  . 0.177 . . 0.174 . . . . . 0.177 . 20 . 0.981 0.964 0.251 
'X-RAY DIFFRACTION' 2.952 3.095  1681 . 78  1594 99.4646  . 0.168 . . 0.165 . . . . . 0.171 . 20 . 0.983 0.975 0.217 
'X-RAY DIFFRACTION' 3.095 3.262  1607 . 72  1527 99.5022  . 0.161 . . 0.157 . . . . . 0.164 . 20 . 0.985 0.966 0.238 
'X-RAY DIFFRACTION' 3.262 3.459  1480 . 101 1371 99.4595  . 0.163 . . 0.160 . . . . . 0.168 . 20 . 0.985 0.974 0.203 
'X-RAY DIFFRACTION' 3.459 3.696  1433 . 80  1335 98.7439  . 0.160 . . 0.158 . . . . . 0.169 . 20 . 0.987 0.980 0.183 
'X-RAY DIFFRACTION' 3.696 3.990  1324 . 69  1217 97.1299  . 0.172 . . 0.170 . . . . . 0.182 . 20 . 0.984 0.977 0.205 
'X-RAY DIFFRACTION' 3.990 4.367  1222 . 57  1165 100.0000 . 0.152 . . 0.151 . . . . . 0.168 . 20 . 0.987 0.984 0.174 
'X-RAY DIFFRACTION' 4.367 4.877  1116 . 44  1072 100.0000 . 0.145 . . 0.146 . . . . . 0.168 . 20 . 0.989 0.990 0.127 
'X-RAY DIFFRACTION' 4.877 5.621  985  . 39  938  99.1878  . 0.176 . . 0.175 . . . . . 0.196 . 20 . 0.985 0.979 0.194 
'X-RAY DIFFRACTION' 5.621 6.859  832  . 31  779  97.3558  . 0.204 . . 0.201 . . . . . 0.219 . 20 . 0.980 0.967 0.290 
'X-RAY DIFFRACTION' 6.859 9.594  661  . 27  619  97.7307  . 0.158 . . 0.157 . . . . . 0.176 . 20 . 0.989 0.984 0.182 
'X-RAY DIFFRACTION' 9.594 45.884 396  . 19  372  98.7374  . 0.213 . . 0.217 . . . . . 0.250 . 20 . 0.972 0.989 0.145 
# 
_struct.entry_id                     9F2V 
_struct.title                        'Crystal structure of SARS-CoV-2 Mpro in complex with RHTCR02' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9F2V 
_struct_keywords.text            'Complex, ANTIVIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'ANTIVIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    R1AB_SARS2 
_struct_ref.pdbx_db_accession          P0DTD1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
_struct_ref.pdbx_align_begin           3264 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9F2V A 1 ? 306 ? P0DTD1 3264 ? 3569 ? 1 306 
2 1 9F2V B 1 ? 306 ? P0DTD1 3264 ? 3569 ? 1 306 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3160  ? 
1 MORE         -13   ? 
1 'SSA (A^2)'  25250 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 10  ? GLY A 15  ? SER A 10  GLY A 15  1 ? 6  
HELX_P HELX_P2  AA2 HIS A 41  ? CYS A 44  ? HIS A 41  CYS A 44  5 ? 4  
HELX_P HELX_P3  AA3 THR A 45  ? MET A 49  ? THR A 45  MET A 49  5 ? 5  
HELX_P HELX_P4  AA4 ASN A 53  ? ARG A 60  ? ASN A 53  ARG A 60  1 ? 8  
HELX_P HELX_P5  AA5 SER A 62  ? HIS A 64  ? SER A 62  HIS A 64  5 ? 3  
HELX_P HELX_P6  AA6 ILE A 200 ? ASN A 214 ? ILE A 200 ASN A 214 1 ? 15 
HELX_P HELX_P7  AA7 THR A 226 ? MET A 235 ? THR A 226 MET A 235 1 ? 10 
HELX_P HELX_P8  AA8 LYS A 236 ? ASN A 238 ? LYS A 236 ASN A 238 5 ? 3  
HELX_P HELX_P9  AA9 THR A 243 ? LEU A 250 ? THR A 243 LEU A 250 1 ? 8  
HELX_P HELX_P10 AB1 LEU A 250 ? GLY A 258 ? LEU A 250 GLY A 258 1 ? 9  
HELX_P HELX_P11 AB2 ALA A 260 ? GLY A 275 ? ALA A 260 GLY A 275 1 ? 16 
HELX_P HELX_P12 AB3 THR A 292 ? GLY A 302 ? THR A 292 GLY A 302 1 ? 11 
HELX_P HELX_P13 AB4 SER B 10  ? GLY B 15  ? SER B 10  GLY B 15  1 ? 6  
HELX_P HELX_P14 AB5 HIS B 41  ? CYS B 44  ? HIS B 41  CYS B 44  5 ? 4  
HELX_P HELX_P15 AB6 SER B 46  ? ASN B 51  ? SER B 46  ASN B 51  5 ? 6  
HELX_P HELX_P16 AB7 ASN B 53  ? ARG B 60  ? ASN B 53  ARG B 60  1 ? 8  
HELX_P HELX_P17 AB8 SER B 62  ? HIS B 64  ? SER B 62  HIS B 64  5 ? 3  
HELX_P HELX_P18 AB9 ILE B 200 ? ASN B 214 ? ILE B 200 ASN B 214 1 ? 15 
HELX_P HELX_P19 AC1 THR B 226 ? MET B 235 ? THR B 226 MET B 235 1 ? 10 
HELX_P HELX_P20 AC2 LYS B 236 ? ASN B 238 ? LYS B 236 ASN B 238 5 ? 3  
HELX_P HELX_P21 AC3 THR B 243 ? LEU B 250 ? THR B 243 LEU B 250 1 ? 8  
HELX_P HELX_P22 AC4 LEU B 250 ? GLY B 258 ? LEU B 250 GLY B 258 1 ? 9  
HELX_P HELX_P23 AC5 ALA B 260 ? GLY B 275 ? ALA B 260 GLY B 275 1 ? 16 
HELX_P HELX_P24 AC6 THR B 292 ? GLY B 302 ? THR B 292 GLY B 302 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale none ? A CYS 145 SG ? ? ? 1_555 C A1H9E . C19 ? ? A CYS 145 A A1H9E 401 1_555 ? ? ? ? ? ? ? 1.927 ? ? 
covale2 covale none ? B CYS 145 SG ? ? ? 1_555 D A1H9E . C19 ? ? B CYS 145 B A1H9E 401 1_555 ? ? ? ? ? ? ? 1.973 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 A1H9E C . ? CYS A 145 ? A1H9E A 401 ? 1_555 CYS A 145 ? 1_555 C19 SG CYS 1 A1H9E None 'Covalent chemical modification' 
2 A1H9E D . ? CYS B 145 ? A1H9E B 401 ? 1_555 CYS B 145 ? 1_555 C19 SG CYS 1 A1H9E None 'Covalent chemical modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 5 ? 
AA3 ? 3 ? 
AA4 ? 7 ? 
AA5 ? 5 ? 
AA6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 73  ? LEU A 75  ? VAL A 73  LEU A 75  
AA1 2 PHE A 66  ? ALA A 70  ? PHE A 66  ALA A 70  
AA1 3 MET A 17  ? CYS A 22  ? MET A 17  CYS A 22  
AA1 4 THR A 25  ? LEU A 32  ? THR A 25  LEU A 32  
AA1 5 VAL A 35  ? PRO A 39  ? VAL A 35  PRO A 39  
AA1 6 VAL A 86  ? VAL A 91  ? VAL A 86  VAL A 91  
AA1 7 VAL A 77  ? GLN A 83  ? VAL A 77  GLN A 83  
AA2 1 LYS A 100 ? PHE A 103 ? LYS A 100 PHE A 103 
AA2 2 CYS A 156 ? LEU A 167 ? CYS A 156 LEU A 167 
AA2 3 VAL A 148 ? ASP A 153 ? VAL A 148 ASP A 153 
AA2 4 THR A 111 ? TYR A 118 ? THR A 111 TYR A 118 
AA2 5 SER A 121 ? ALA A 129 ? SER A 121 ALA A 129 
AA3 1 LYS A 100 ? PHE A 103 ? LYS A 100 PHE A 103 
AA3 2 CYS A 156 ? LEU A 167 ? CYS A 156 LEU A 167 
AA3 3 VAL A 171 ? THR A 175 ? VAL A 171 THR A 175 
AA4 1 VAL B 73  ? LEU B 75  ? VAL B 73  LEU B 75  
AA4 2 PHE B 66  ? ALA B 70  ? PHE B 66  ALA B 70  
AA4 3 MET B 17  ? CYS B 22  ? MET B 17  CYS B 22  
AA4 4 THR B 25  ? LEU B 32  ? THR B 25  LEU B 32  
AA4 5 VAL B 35  ? PRO B 39  ? VAL B 35  PRO B 39  
AA4 6 VAL B 86  ? VAL B 91  ? VAL B 86  VAL B 91  
AA4 7 VAL B 77  ? GLN B 83  ? VAL B 77  GLN B 83  
AA5 1 LYS B 100 ? PHE B 103 ? LYS B 100 PHE B 103 
AA5 2 CYS B 156 ? LEU B 167 ? CYS B 156 LEU B 167 
AA5 3 VAL B 148 ? ASP B 153 ? VAL B 148 ASP B 153 
AA5 4 THR B 111 ? TYR B 118 ? THR B 111 TYR B 118 
AA5 5 SER B 121 ? ALA B 129 ? SER B 121 ALA B 129 
AA6 1 LYS B 100 ? PHE B 103 ? LYS B 100 PHE B 103 
AA6 2 CYS B 156 ? LEU B 167 ? CYS B 156 LEU B 167 
AA6 3 VAL B 171 ? THR B 175 ? VAL B 171 THR B 175 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 75  ? O LEU A 75  N VAL A 68  ? N VAL A 68  
AA1 2 3 O LEU A 67  ? O LEU A 67  N THR A 21  ? N THR A 21  
AA1 3 4 N VAL A 20  ? N VAL A 20  O LEU A 27  ? O LEU A 27  
AA1 4 5 N LEU A 30  ? N LEU A 30  O TYR A 37  ? O TYR A 37  
AA1 5 6 N CYS A 38  ? N CYS A 38  O LEU A 87  ? O LEU A 87  
AA1 6 7 O LYS A 88  ? O LYS A 88  N SER A 81  ? N SER A 81  
AA2 1 2 N LYS A 100 ? N LYS A 100 O VAL A 157 ? O VAL A 157 
AA2 2 3 O CYS A 156 ? O CYS A 156 N ASP A 153 ? N ASP A 153 
AA2 3 4 O PHE A 150 ? O PHE A 150 N SER A 113 ? N SER A 113 
AA2 4 5 N VAL A 114 ? N VAL A 114 O TYR A 126 ? O TYR A 126 
AA3 1 2 N LYS A 100 ? N LYS A 100 O VAL A 157 ? O VAL A 157 
AA3 2 3 N LEU A 167 ? N LEU A 167 O VAL A 171 ? O VAL A 171 
AA4 1 2 O VAL B 73  ? O VAL B 73  N ALA B 70  ? N ALA B 70  
AA4 2 3 O LEU B 67  ? O LEU B 67  N THR B 21  ? N THR B 21  
AA4 3 4 N VAL B 20  ? N VAL B 20  O LEU B 27  ? O LEU B 27  
AA4 4 5 N LEU B 30  ? N LEU B 30  O TYR B 37  ? O TYR B 37  
AA4 5 6 N CYS B 38  ? N CYS B 38  O LEU B 87  ? O LEU B 87  
AA4 6 7 O LYS B 88  ? O LYS B 88  N SER B 81  ? N SER B 81  
AA5 1 2 N LYS B 100 ? N LYS B 100 O VAL B 157 ? O VAL B 157 
AA5 2 3 O SER B 158 ? O SER B 158 N ASN B 151 ? N ASN B 151 
AA5 3 4 O PHE B 150 ? O PHE B 150 N SER B 113 ? N SER B 113 
AA5 4 5 N VAL B 114 ? N VAL B 114 O TYR B 126 ? O TYR B 126 
AA6 1 2 N LYS B 100 ? N LYS B 100 O VAL B 157 ? O VAL B 157 
AA6 2 3 N LEU B 167 ? N LEU B 167 O VAL B 171 ? O VAL B 171 
# 
_pdbx_entry_details.entry_id                   9F2V 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   SG 
_pdbx_validate_close_contact.auth_asym_id_1   B 
_pdbx_validate_close_contact.auth_comp_id_1   CYS 
_pdbx_validate_close_contact.auth_seq_id_1    145 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   C17 
_pdbx_validate_close_contact.auth_asym_id_2   B 
_pdbx_validate_close_contact.auth_comp_id_2   A1H9E 
_pdbx_validate_close_contact.auth_seq_id_2    401 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 33  ? ? 53.44   -133.82 
2  1 ASN A 51  ? ? -156.47 62.79   
3  1 ASN A 84  ? ? 53.36   -124.89 
4  1 TYR A 154 ? ? 72.47   -93.75  
5  1 PRO A 184 ? ? -91.76  38.52   
6  1 ASP B 33  ? ? 51.27   -126.21 
7  1 ASN B 84  ? ? 55.49   -120.84 
8  1 TYR B 154 ? ? 62.93   -104.88 
9  1 THR B 169 ? ? 98.47   -11.84  
10 1 GLN B 189 ? ? -68.94  97.55   
# 
_pdbx_validate_chiral.id              1 
_pdbx_validate_chiral.PDB_model_num   1 
_pdbx_validate_chiral.auth_atom_id    C19 
_pdbx_validate_chiral.label_alt_id    ? 
_pdbx_validate_chiral.auth_asym_id    A 
_pdbx_validate_chiral.auth_comp_id    A1H9E 
_pdbx_validate_chiral.auth_seq_id     401 
_pdbx_validate_chiral.PDB_ins_code    ? 
_pdbx_validate_chiral.details         PLANAR 
_pdbx_validate_chiral.omega           . 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    B 
_pdbx_validate_planes.auth_seq_id     222 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.092 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 B PHE 305 ? B PHE 305 
2 1 Y 1 B GLN 306 ? B GLN 306 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1H9E N1   N N N 1   
A1H9E N3   N N N 2   
A1H9E C4   C N N 3   
A1H9E C5   C N N 4   
A1H9E C6   C N N 5   
A1H9E C7   C N N 6   
A1H9E C8   C N N 7   
A1H9E C10  C N N 8   
A1H9E C13  C N N 9   
A1H9E C15  C N N 10  
A1H9E C17  C N R 11  
A1H9E C20  C N N 12  
A1H9E C21  C N S 13  
A1H9E C22  C N N 14  
A1H9E C24  C N N 15  
A1H9E O7   O N N 16  
A1H9E N4   N N N 17  
A1H9E C19  C N S 18  
A1H9E O6   O N N 19  
A1H9E C18  C N N 20  
A1H9E C23  C N N 21  
A1H9E N5   N N N 22  
A1H9E O5   O N N 23  
A1H9E O4   O N N 24  
A1H9E C11  C N S 25  
A1H9E C12  C N N 26  
A1H9E C14  C N N 27  
A1H9E C16  C N N 28  
A1H9E O2   O N N 29  
A1H9E C3   C N N 30  
A1H9E C2   C N N 31  
A1H9E F1   F N N 32  
A1H9E C1   C N N 33  
A1H9E N2   N N N 34  
A1H9E O3   O N N 35  
A1H9E O1   O N N 36  
A1H9E C9   C N N 37  
A1H9E H2   H N N 38  
A1H9E H83  H N N 39  
A1H9E H81  H N N 40  
A1H9E H82  H N N 41  
A1H9E H101 H N N 42  
A1H9E H103 H N N 43  
A1H9E H102 H N N 44  
A1H9E H152 H N N 45  
A1H9E H151 H N N 46  
A1H9E H17  H N N 47  
A1H9E H21  H N N 48  
A1H9E H242 H N N 49  
A1H9E H241 H N N 50  
A1H9E HN42 H N N 51  
A1H9E HN41 H N N 52  
A1H9E H19  H N N 53  
A1H9E HO6  H N N 54  
A1H9E H182 H N N 55  
A1H9E H181 H N N 56  
A1H9E H231 H N N 57  
A1H9E H232 H N N 58  
A1H9E H4   H N N 59  
A1H9E H11  H N N 60  
A1H9E H121 H N N 61  
A1H9E H122 H N N 62  
A1H9E H14  H N N 63  
A1H9E H161 H N N 64  
A1H9E H162 H N N 65  
A1H9E H3   H N N 66  
A1H9E H1   H N N 67  
A1H9E H5   H N N 68  
A1H9E H93  H N N 69  
A1H9E H91  H N N 70  
A1H9E H92  H N N 71  
ALA   N    N N N 72  
ALA   CA   C N S 73  
ALA   C    C N N 74  
ALA   O    O N N 75  
ALA   CB   C N N 76  
ALA   OXT  O N N 77  
ALA   H    H N N 78  
ALA   H2   H N N 79  
ALA   HA   H N N 80  
ALA   HB1  H N N 81  
ALA   HB2  H N N 82  
ALA   HB3  H N N 83  
ALA   HXT  H N N 84  
ARG   N    N N N 85  
ARG   CA   C N S 86  
ARG   C    C N N 87  
ARG   O    O N N 88  
ARG   CB   C N N 89  
ARG   CG   C N N 90  
ARG   CD   C N N 91  
ARG   NE   N N N 92  
ARG   CZ   C N N 93  
ARG   NH1  N N N 94  
ARG   NH2  N N N 95  
ARG   OXT  O N N 96  
ARG   H    H N N 97  
ARG   H2   H N N 98  
ARG   HA   H N N 99  
ARG   HB2  H N N 100 
ARG   HB3  H N N 101 
ARG   HG2  H N N 102 
ARG   HG3  H N N 103 
ARG   HD2  H N N 104 
ARG   HD3  H N N 105 
ARG   HE   H N N 106 
ARG   HH11 H N N 107 
ARG   HH12 H N N 108 
ARG   HH21 H N N 109 
ARG   HH22 H N N 110 
ARG   HXT  H N N 111 
ASN   N    N N N 112 
ASN   CA   C N S 113 
ASN   C    C N N 114 
ASN   O    O N N 115 
ASN   CB   C N N 116 
ASN   CG   C N N 117 
ASN   OD1  O N N 118 
ASN   ND2  N N N 119 
ASN   OXT  O N N 120 
ASN   H    H N N 121 
ASN   H2   H N N 122 
ASN   HA   H N N 123 
ASN   HB2  H N N 124 
ASN   HB3  H N N 125 
ASN   HD21 H N N 126 
ASN   HD22 H N N 127 
ASN   HXT  H N N 128 
ASP   N    N N N 129 
ASP   CA   C N S 130 
ASP   C    C N N 131 
ASP   O    O N N 132 
ASP   CB   C N N 133 
ASP   CG   C N N 134 
ASP   OD1  O N N 135 
ASP   OD2  O N N 136 
ASP   OXT  O N N 137 
ASP   H    H N N 138 
ASP   H2   H N N 139 
ASP   HA   H N N 140 
ASP   HB2  H N N 141 
ASP   HB3  H N N 142 
ASP   HD2  H N N 143 
ASP   HXT  H N N 144 
CYS   N    N N N 145 
CYS   CA   C N R 146 
CYS   C    C N N 147 
CYS   O    O N N 148 
CYS   CB   C N N 149 
CYS   SG   S N N 150 
CYS   OXT  O N N 151 
CYS   H    H N N 152 
CYS   H2   H N N 153 
CYS   HA   H N N 154 
CYS   HB2  H N N 155 
CYS   HB3  H N N 156 
CYS   HG   H N N 157 
CYS   HXT  H N N 158 
GLN   N    N N N 159 
GLN   CA   C N S 160 
GLN   C    C N N 161 
GLN   O    O N N 162 
GLN   CB   C N N 163 
GLN   CG   C N N 164 
GLN   CD   C N N 165 
GLN   OE1  O N N 166 
GLN   NE2  N N N 167 
GLN   OXT  O N N 168 
GLN   H    H N N 169 
GLN   H2   H N N 170 
GLN   HA   H N N 171 
GLN   HB2  H N N 172 
GLN   HB3  H N N 173 
GLN   HG2  H N N 174 
GLN   HG3  H N N 175 
GLN   HE21 H N N 176 
GLN   HE22 H N N 177 
GLN   HXT  H N N 178 
GLU   N    N N N 179 
GLU   CA   C N S 180 
GLU   C    C N N 181 
GLU   O    O N N 182 
GLU   CB   C N N 183 
GLU   CG   C N N 184 
GLU   CD   C N N 185 
GLU   OE1  O N N 186 
GLU   OE2  O N N 187 
GLU   OXT  O N N 188 
GLU   H    H N N 189 
GLU   H2   H N N 190 
GLU   HA   H N N 191 
GLU   HB2  H N N 192 
GLU   HB3  H N N 193 
GLU   HG2  H N N 194 
GLU   HG3  H N N 195 
GLU   HE2  H N N 196 
GLU   HXT  H N N 197 
GLY   N    N N N 198 
GLY   CA   C N N 199 
GLY   C    C N N 200 
GLY   O    O N N 201 
GLY   OXT  O N N 202 
GLY   H    H N N 203 
GLY   H2   H N N 204 
GLY   HA2  H N N 205 
GLY   HA3  H N N 206 
GLY   HXT  H N N 207 
HIS   N    N N N 208 
HIS   CA   C N S 209 
HIS   C    C N N 210 
HIS   O    O N N 211 
HIS   CB   C N N 212 
HIS   CG   C Y N 213 
HIS   ND1  N Y N 214 
HIS   CD2  C Y N 215 
HIS   CE1  C Y N 216 
HIS   NE2  N Y N 217 
HIS   OXT  O N N 218 
HIS   H    H N N 219 
HIS   H2   H N N 220 
HIS   HA   H N N 221 
HIS   HB2  H N N 222 
HIS   HB3  H N N 223 
HIS   HD1  H N N 224 
HIS   HD2  H N N 225 
HIS   HE1  H N N 226 
HIS   HE2  H N N 227 
HIS   HXT  H N N 228 
HOH   O    O N N 229 
HOH   H1   H N N 230 
HOH   H2   H N N 231 
ILE   N    N N N 232 
ILE   CA   C N S 233 
ILE   C    C N N 234 
ILE   O    O N N 235 
ILE   CB   C N S 236 
ILE   CG1  C N N 237 
ILE   CG2  C N N 238 
ILE   CD1  C N N 239 
ILE   OXT  O N N 240 
ILE   H    H N N 241 
ILE   H2   H N N 242 
ILE   HA   H N N 243 
ILE   HB   H N N 244 
ILE   HG12 H N N 245 
ILE   HG13 H N N 246 
ILE   HG21 H N N 247 
ILE   HG22 H N N 248 
ILE   HG23 H N N 249 
ILE   HD11 H N N 250 
ILE   HD12 H N N 251 
ILE   HD13 H N N 252 
ILE   HXT  H N N 253 
LEU   N    N N N 254 
LEU   CA   C N S 255 
LEU   C    C N N 256 
LEU   O    O N N 257 
LEU   CB   C N N 258 
LEU   CG   C N N 259 
LEU   CD1  C N N 260 
LEU   CD2  C N N 261 
LEU   OXT  O N N 262 
LEU   H    H N N 263 
LEU   H2   H N N 264 
LEU   HA   H N N 265 
LEU   HB2  H N N 266 
LEU   HB3  H N N 267 
LEU   HG   H N N 268 
LEU   HD11 H N N 269 
LEU   HD12 H N N 270 
LEU   HD13 H N N 271 
LEU   HD21 H N N 272 
LEU   HD22 H N N 273 
LEU   HD23 H N N 274 
LEU   HXT  H N N 275 
LYS   N    N N N 276 
LYS   CA   C N S 277 
LYS   C    C N N 278 
LYS   O    O N N 279 
LYS   CB   C N N 280 
LYS   CG   C N N 281 
LYS   CD   C N N 282 
LYS   CE   C N N 283 
LYS   NZ   N N N 284 
LYS   OXT  O N N 285 
LYS   H    H N N 286 
LYS   H2   H N N 287 
LYS   HA   H N N 288 
LYS   HB2  H N N 289 
LYS   HB3  H N N 290 
LYS   HG2  H N N 291 
LYS   HG3  H N N 292 
LYS   HD2  H N N 293 
LYS   HD3  H N N 294 
LYS   HE2  H N N 295 
LYS   HE3  H N N 296 
LYS   HZ1  H N N 297 
LYS   HZ2  H N N 298 
LYS   HZ3  H N N 299 
LYS   HXT  H N N 300 
MET   N    N N N 301 
MET   CA   C N S 302 
MET   C    C N N 303 
MET   O    O N N 304 
MET   CB   C N N 305 
MET   CG   C N N 306 
MET   SD   S N N 307 
MET   CE   C N N 308 
MET   OXT  O N N 309 
MET   H    H N N 310 
MET   H2   H N N 311 
MET   HA   H N N 312 
MET   HB2  H N N 313 
MET   HB3  H N N 314 
MET   HG2  H N N 315 
MET   HG3  H N N 316 
MET   HE1  H N N 317 
MET   HE2  H N N 318 
MET   HE3  H N N 319 
MET   HXT  H N N 320 
PHE   N    N N N 321 
PHE   CA   C N S 322 
PHE   C    C N N 323 
PHE   O    O N N 324 
PHE   CB   C N N 325 
PHE   CG   C Y N 326 
PHE   CD1  C Y N 327 
PHE   CD2  C Y N 328 
PHE   CE1  C Y N 329 
PHE   CE2  C Y N 330 
PHE   CZ   C Y N 331 
PHE   OXT  O N N 332 
PHE   H    H N N 333 
PHE   H2   H N N 334 
PHE   HA   H N N 335 
PHE   HB2  H N N 336 
PHE   HB3  H N N 337 
PHE   HD1  H N N 338 
PHE   HD2  H N N 339 
PHE   HE1  H N N 340 
PHE   HE2  H N N 341 
PHE   HZ   H N N 342 
PHE   HXT  H N N 343 
PRO   N    N N N 344 
PRO   CA   C N S 345 
PRO   C    C N N 346 
PRO   O    O N N 347 
PRO   CB   C N N 348 
PRO   CG   C N N 349 
PRO   CD   C N N 350 
PRO   OXT  O N N 351 
PRO   H    H N N 352 
PRO   HA   H N N 353 
PRO   HB2  H N N 354 
PRO   HB3  H N N 355 
PRO   HG2  H N N 356 
PRO   HG3  H N N 357 
PRO   HD2  H N N 358 
PRO   HD3  H N N 359 
PRO   HXT  H N N 360 
SER   N    N N N 361 
SER   CA   C N S 362 
SER   C    C N N 363 
SER   O    O N N 364 
SER   CB   C N N 365 
SER   OG   O N N 366 
SER   OXT  O N N 367 
SER   H    H N N 368 
SER   H2   H N N 369 
SER   HA   H N N 370 
SER   HB2  H N N 371 
SER   HB3  H N N 372 
SER   HG   H N N 373 
SER   HXT  H N N 374 
THR   N    N N N 375 
THR   CA   C N S 376 
THR   C    C N N 377 
THR   O    O N N 378 
THR   CB   C N R 379 
THR   OG1  O N N 380 
THR   CG2  C N N 381 
THR   OXT  O N N 382 
THR   H    H N N 383 
THR   H2   H N N 384 
THR   HA   H N N 385 
THR   HB   H N N 386 
THR   HG1  H N N 387 
THR   HG21 H N N 388 
THR   HG22 H N N 389 
THR   HG23 H N N 390 
THR   HXT  H N N 391 
TRP   N    N N N 392 
TRP   CA   C N S 393 
TRP   C    C N N 394 
TRP   O    O N N 395 
TRP   CB   C N N 396 
TRP   CG   C Y N 397 
TRP   CD1  C Y N 398 
TRP   CD2  C Y N 399 
TRP   NE1  N Y N 400 
TRP   CE2  C Y N 401 
TRP   CE3  C Y N 402 
TRP   CZ2  C Y N 403 
TRP   CZ3  C Y N 404 
TRP   CH2  C Y N 405 
TRP   OXT  O N N 406 
TRP   H    H N N 407 
TRP   H2   H N N 408 
TRP   HA   H N N 409 
TRP   HB2  H N N 410 
TRP   HB3  H N N 411 
TRP   HD1  H N N 412 
TRP   HE1  H N N 413 
TRP   HE3  H N N 414 
TRP   HZ2  H N N 415 
TRP   HZ3  H N N 416 
TRP   HH2  H N N 417 
TRP   HXT  H N N 418 
TYR   N    N N N 419 
TYR   CA   C N S 420 
TYR   C    C N N 421 
TYR   O    O N N 422 
TYR   CB   C N N 423 
TYR   CG   C Y N 424 
TYR   CD1  C Y N 425 
TYR   CD2  C Y N 426 
TYR   CE1  C Y N 427 
TYR   CE2  C Y N 428 
TYR   CZ   C Y N 429 
TYR   OH   O N N 430 
TYR   OXT  O N N 431 
TYR   H    H N N 432 
TYR   H2   H N N 433 
TYR   HA   H N N 434 
TYR   HB2  H N N 435 
TYR   HB3  H N N 436 
TYR   HD1  H N N 437 
TYR   HD2  H N N 438 
TYR   HE1  H N N 439 
TYR   HE2  H N N 440 
TYR   HH   H N N 441 
TYR   HXT  H N N 442 
VAL   N    N N N 443 
VAL   CA   C N S 444 
VAL   C    C N N 445 
VAL   O    O N N 446 
VAL   CB   C N N 447 
VAL   CG1  C N N 448 
VAL   CG2  C N N 449 
VAL   OXT  O N N 450 
VAL   H    H N N 451 
VAL   H2   H N N 452 
VAL   HA   H N N 453 
VAL   HB   H N N 454 
VAL   HG11 H N N 455 
VAL   HG12 H N N 456 
VAL   HG13 H N N 457 
VAL   HG21 H N N 458 
VAL   HG22 H N N 459 
VAL   HG23 H N N 460 
VAL   HXT  H N N 461 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1H9E N1  C1   sing N N 1   
A1H9E C5  N1   sing N N 2   
A1H9E N1  C11  sing N N 3   
A1H9E C1  C2   doub N N 4   
A1H9E C2  C3   sing N N 5   
A1H9E F1  C2   sing N N 6   
A1H9E C3  C4   doub N N 7   
A1H9E C4  C5   sing N N 8   
A1H9E N2  C4   sing N N 9   
A1H9E O2  C5   doub N N 10  
A1H9E C6  N2   sing N N 11  
A1H9E O1  C6   sing N N 12  
A1H9E O3  C6   doub N N 13  
A1H9E C7  O1   sing N N 14  
A1H9E C8  C7   sing N N 15  
A1H9E C9  C7   sing N N 16  
A1H9E C10 C7   sing N N 17  
A1H9E C12 C11  sing N N 18  
A1H9E C11 C13  sing N N 19  
A1H9E C14 C12  sing N N 20  
A1H9E O4  C13  doub N N 21  
A1H9E C13 N3   sing N N 22  
A1H9E C14 C15  sing N N 23  
A1H9E C16 C14  sing N N 24  
A1H9E C15 C16  sing N N 25  
A1H9E N3  C17  sing N N 26  
A1H9E C18 C17  sing N N 27  
A1H9E C17 C19  sing N N 28  
A1H9E C21 C18  sing N N 29  
A1H9E C19 C20  sing N N 30  
A1H9E O6  C19  sing N N 31  
A1H9E N4  C20  sing N N 32  
A1H9E C20 O7   doub N N 33  
A1H9E C21 C22  sing N N 34  
A1H9E C24 C21  sing N N 35  
A1H9E C22 N5   sing N N 36  
A1H9E O5  C22  doub N N 37  
A1H9E N5  C23  sing N N 38  
A1H9E C23 C24  sing N N 39  
A1H9E N3  H2   sing N N 40  
A1H9E C8  H83  sing N N 41  
A1H9E C8  H81  sing N N 42  
A1H9E C8  H82  sing N N 43  
A1H9E C10 H101 sing N N 44  
A1H9E C10 H103 sing N N 45  
A1H9E C10 H102 sing N N 46  
A1H9E C15 H152 sing N N 47  
A1H9E C15 H151 sing N N 48  
A1H9E C17 H17  sing N N 49  
A1H9E C21 H21  sing N N 50  
A1H9E C24 H242 sing N N 51  
A1H9E C24 H241 sing N N 52  
A1H9E N4  HN42 sing N N 53  
A1H9E N4  HN41 sing N N 54  
A1H9E C19 H19  sing N N 55  
A1H9E O6  HO6  sing N N 56  
A1H9E C18 H182 sing N N 57  
A1H9E C18 H181 sing N N 58  
A1H9E C23 H231 sing N N 59  
A1H9E C23 H232 sing N N 60  
A1H9E N5  H4   sing N N 61  
A1H9E C11 H11  sing N N 62  
A1H9E C12 H121 sing N N 63  
A1H9E C12 H122 sing N N 64  
A1H9E C14 H14  sing N N 65  
A1H9E C16 H161 sing N N 66  
A1H9E C16 H162 sing N N 67  
A1H9E C3  H3   sing N N 68  
A1H9E C1  H1   sing N N 69  
A1H9E N2  H5   sing N N 70  
A1H9E C9  H93  sing N N 71  
A1H9E C9  H91  sing N N 72  
A1H9E C9  H92  sing N N 73  
ALA   N   CA   sing N N 74  
ALA   N   H    sing N N 75  
ALA   N   H2   sing N N 76  
ALA   CA  C    sing N N 77  
ALA   CA  CB   sing N N 78  
ALA   CA  HA   sing N N 79  
ALA   C   O    doub N N 80  
ALA   C   OXT  sing N N 81  
ALA   CB  HB1  sing N N 82  
ALA   CB  HB2  sing N N 83  
ALA   CB  HB3  sing N N 84  
ALA   OXT HXT  sing N N 85  
ARG   N   CA   sing N N 86  
ARG   N   H    sing N N 87  
ARG   N   H2   sing N N 88  
ARG   CA  C    sing N N 89  
ARG   CA  CB   sing N N 90  
ARG   CA  HA   sing N N 91  
ARG   C   O    doub N N 92  
ARG   C   OXT  sing N N 93  
ARG   CB  CG   sing N N 94  
ARG   CB  HB2  sing N N 95  
ARG   CB  HB3  sing N N 96  
ARG   CG  CD   sing N N 97  
ARG   CG  HG2  sing N N 98  
ARG   CG  HG3  sing N N 99  
ARG   CD  NE   sing N N 100 
ARG   CD  HD2  sing N N 101 
ARG   CD  HD3  sing N N 102 
ARG   NE  CZ   sing N N 103 
ARG   NE  HE   sing N N 104 
ARG   CZ  NH1  sing N N 105 
ARG   CZ  NH2  doub N N 106 
ARG   NH1 HH11 sing N N 107 
ARG   NH1 HH12 sing N N 108 
ARG   NH2 HH21 sing N N 109 
ARG   NH2 HH22 sing N N 110 
ARG   OXT HXT  sing N N 111 
ASN   N   CA   sing N N 112 
ASN   N   H    sing N N 113 
ASN   N   H2   sing N N 114 
ASN   CA  C    sing N N 115 
ASN   CA  CB   sing N N 116 
ASN   CA  HA   sing N N 117 
ASN   C   O    doub N N 118 
ASN   C   OXT  sing N N 119 
ASN   CB  CG   sing N N 120 
ASN   CB  HB2  sing N N 121 
ASN   CB  HB3  sing N N 122 
ASN   CG  OD1  doub N N 123 
ASN   CG  ND2  sing N N 124 
ASN   ND2 HD21 sing N N 125 
ASN   ND2 HD22 sing N N 126 
ASN   OXT HXT  sing N N 127 
ASP   N   CA   sing N N 128 
ASP   N   H    sing N N 129 
ASP   N   H2   sing N N 130 
ASP   CA  C    sing N N 131 
ASP   CA  CB   sing N N 132 
ASP   CA  HA   sing N N 133 
ASP   C   O    doub N N 134 
ASP   C   OXT  sing N N 135 
ASP   CB  CG   sing N N 136 
ASP   CB  HB2  sing N N 137 
ASP   CB  HB3  sing N N 138 
ASP   CG  OD1  doub N N 139 
ASP   CG  OD2  sing N N 140 
ASP   OD2 HD2  sing N N 141 
ASP   OXT HXT  sing N N 142 
CYS   N   CA   sing N N 143 
CYS   N   H    sing N N 144 
CYS   N   H2   sing N N 145 
CYS   CA  C    sing N N 146 
CYS   CA  CB   sing N N 147 
CYS   CA  HA   sing N N 148 
CYS   C   O    doub N N 149 
CYS   C   OXT  sing N N 150 
CYS   CB  SG   sing N N 151 
CYS   CB  HB2  sing N N 152 
CYS   CB  HB3  sing N N 153 
CYS   SG  HG   sing N N 154 
CYS   OXT HXT  sing N N 155 
GLN   N   CA   sing N N 156 
GLN   N   H    sing N N 157 
GLN   N   H2   sing N N 158 
GLN   CA  C    sing N N 159 
GLN   CA  CB   sing N N 160 
GLN   CA  HA   sing N N 161 
GLN   C   O    doub N N 162 
GLN   C   OXT  sing N N 163 
GLN   CB  CG   sing N N 164 
GLN   CB  HB2  sing N N 165 
GLN   CB  HB3  sing N N 166 
GLN   CG  CD   sing N N 167 
GLN   CG  HG2  sing N N 168 
GLN   CG  HG3  sing N N 169 
GLN   CD  OE1  doub N N 170 
GLN   CD  NE2  sing N N 171 
GLN   NE2 HE21 sing N N 172 
GLN   NE2 HE22 sing N N 173 
GLN   OXT HXT  sing N N 174 
GLU   N   CA   sing N N 175 
GLU   N   H    sing N N 176 
GLU   N   H2   sing N N 177 
GLU   CA  C    sing N N 178 
GLU   CA  CB   sing N N 179 
GLU   CA  HA   sing N N 180 
GLU   C   O    doub N N 181 
GLU   C   OXT  sing N N 182 
GLU   CB  CG   sing N N 183 
GLU   CB  HB2  sing N N 184 
GLU   CB  HB3  sing N N 185 
GLU   CG  CD   sing N N 186 
GLU   CG  HG2  sing N N 187 
GLU   CG  HG3  sing N N 188 
GLU   CD  OE1  doub N N 189 
GLU   CD  OE2  sing N N 190 
GLU   OE2 HE2  sing N N 191 
GLU   OXT HXT  sing N N 192 
GLY   N   CA   sing N N 193 
GLY   N   H    sing N N 194 
GLY   N   H2   sing N N 195 
GLY   CA  C    sing N N 196 
GLY   CA  HA2  sing N N 197 
GLY   CA  HA3  sing N N 198 
GLY   C   O    doub N N 199 
GLY   C   OXT  sing N N 200 
GLY   OXT HXT  sing N N 201 
HIS   N   CA   sing N N 202 
HIS   N   H    sing N N 203 
HIS   N   H2   sing N N 204 
HIS   CA  C    sing N N 205 
HIS   CA  CB   sing N N 206 
HIS   CA  HA   sing N N 207 
HIS   C   O    doub N N 208 
HIS   C   OXT  sing N N 209 
HIS   CB  CG   sing N N 210 
HIS   CB  HB2  sing N N 211 
HIS   CB  HB3  sing N N 212 
HIS   CG  ND1  sing Y N 213 
HIS   CG  CD2  doub Y N 214 
HIS   ND1 CE1  doub Y N 215 
HIS   ND1 HD1  sing N N 216 
HIS   CD2 NE2  sing Y N 217 
HIS   CD2 HD2  sing N N 218 
HIS   CE1 NE2  sing Y N 219 
HIS   CE1 HE1  sing N N 220 
HIS   NE2 HE2  sing N N 221 
HIS   OXT HXT  sing N N 222 
HOH   O   H1   sing N N 223 
HOH   O   H2   sing N N 224 
ILE   N   CA   sing N N 225 
ILE   N   H    sing N N 226 
ILE   N   H2   sing N N 227 
ILE   CA  C    sing N N 228 
ILE   CA  CB   sing N N 229 
ILE   CA  HA   sing N N 230 
ILE   C   O    doub N N 231 
ILE   C   OXT  sing N N 232 
ILE   CB  CG1  sing N N 233 
ILE   CB  CG2  sing N N 234 
ILE   CB  HB   sing N N 235 
ILE   CG1 CD1  sing N N 236 
ILE   CG1 HG12 sing N N 237 
ILE   CG1 HG13 sing N N 238 
ILE   CG2 HG21 sing N N 239 
ILE   CG2 HG22 sing N N 240 
ILE   CG2 HG23 sing N N 241 
ILE   CD1 HD11 sing N N 242 
ILE   CD1 HD12 sing N N 243 
ILE   CD1 HD13 sing N N 244 
ILE   OXT HXT  sing N N 245 
LEU   N   CA   sing N N 246 
LEU   N   H    sing N N 247 
LEU   N   H2   sing N N 248 
LEU   CA  C    sing N N 249 
LEU   CA  CB   sing N N 250 
LEU   CA  HA   sing N N 251 
LEU   C   O    doub N N 252 
LEU   C   OXT  sing N N 253 
LEU   CB  CG   sing N N 254 
LEU   CB  HB2  sing N N 255 
LEU   CB  HB3  sing N N 256 
LEU   CG  CD1  sing N N 257 
LEU   CG  CD2  sing N N 258 
LEU   CG  HG   sing N N 259 
LEU   CD1 HD11 sing N N 260 
LEU   CD1 HD12 sing N N 261 
LEU   CD1 HD13 sing N N 262 
LEU   CD2 HD21 sing N N 263 
LEU   CD2 HD22 sing N N 264 
LEU   CD2 HD23 sing N N 265 
LEU   OXT HXT  sing N N 266 
LYS   N   CA   sing N N 267 
LYS   N   H    sing N N 268 
LYS   N   H2   sing N N 269 
LYS   CA  C    sing N N 270 
LYS   CA  CB   sing N N 271 
LYS   CA  HA   sing N N 272 
LYS   C   O    doub N N 273 
LYS   C   OXT  sing N N 274 
LYS   CB  CG   sing N N 275 
LYS   CB  HB2  sing N N 276 
LYS   CB  HB3  sing N N 277 
LYS   CG  CD   sing N N 278 
LYS   CG  HG2  sing N N 279 
LYS   CG  HG3  sing N N 280 
LYS   CD  CE   sing N N 281 
LYS   CD  HD2  sing N N 282 
LYS   CD  HD3  sing N N 283 
LYS   CE  NZ   sing N N 284 
LYS   CE  HE2  sing N N 285 
LYS   CE  HE3  sing N N 286 
LYS   NZ  HZ1  sing N N 287 
LYS   NZ  HZ2  sing N N 288 
LYS   NZ  HZ3  sing N N 289 
LYS   OXT HXT  sing N N 290 
MET   N   CA   sing N N 291 
MET   N   H    sing N N 292 
MET   N   H2   sing N N 293 
MET   CA  C    sing N N 294 
MET   CA  CB   sing N N 295 
MET   CA  HA   sing N N 296 
MET   C   O    doub N N 297 
MET   C   OXT  sing N N 298 
MET   CB  CG   sing N N 299 
MET   CB  HB2  sing N N 300 
MET   CB  HB3  sing N N 301 
MET   CG  SD   sing N N 302 
MET   CG  HG2  sing N N 303 
MET   CG  HG3  sing N N 304 
MET   SD  CE   sing N N 305 
MET   CE  HE1  sing N N 306 
MET   CE  HE2  sing N N 307 
MET   CE  HE3  sing N N 308 
MET   OXT HXT  sing N N 309 
PHE   N   CA   sing N N 310 
PHE   N   H    sing N N 311 
PHE   N   H2   sing N N 312 
PHE   CA  C    sing N N 313 
PHE   CA  CB   sing N N 314 
PHE   CA  HA   sing N N 315 
PHE   C   O    doub N N 316 
PHE   C   OXT  sing N N 317 
PHE   CB  CG   sing N N 318 
PHE   CB  HB2  sing N N 319 
PHE   CB  HB3  sing N N 320 
PHE   CG  CD1  doub Y N 321 
PHE   CG  CD2  sing Y N 322 
PHE   CD1 CE1  sing Y N 323 
PHE   CD1 HD1  sing N N 324 
PHE   CD2 CE2  doub Y N 325 
PHE   CD2 HD2  sing N N 326 
PHE   CE1 CZ   doub Y N 327 
PHE   CE1 HE1  sing N N 328 
PHE   CE2 CZ   sing Y N 329 
PHE   CE2 HE2  sing N N 330 
PHE   CZ  HZ   sing N N 331 
PHE   OXT HXT  sing N N 332 
PRO   N   CA   sing N N 333 
PRO   N   CD   sing N N 334 
PRO   N   H    sing N N 335 
PRO   CA  C    sing N N 336 
PRO   CA  CB   sing N N 337 
PRO   CA  HA   sing N N 338 
PRO   C   O    doub N N 339 
PRO   C   OXT  sing N N 340 
PRO   CB  CG   sing N N 341 
PRO   CB  HB2  sing N N 342 
PRO   CB  HB3  sing N N 343 
PRO   CG  CD   sing N N 344 
PRO   CG  HG2  sing N N 345 
PRO   CG  HG3  sing N N 346 
PRO   CD  HD2  sing N N 347 
PRO   CD  HD3  sing N N 348 
PRO   OXT HXT  sing N N 349 
SER   N   CA   sing N N 350 
SER   N   H    sing N N 351 
SER   N   H2   sing N N 352 
SER   CA  C    sing N N 353 
SER   CA  CB   sing N N 354 
SER   CA  HA   sing N N 355 
SER   C   O    doub N N 356 
SER   C   OXT  sing N N 357 
SER   CB  OG   sing N N 358 
SER   CB  HB2  sing N N 359 
SER   CB  HB3  sing N N 360 
SER   OG  HG   sing N N 361 
SER   OXT HXT  sing N N 362 
THR   N   CA   sing N N 363 
THR   N   H    sing N N 364 
THR   N   H2   sing N N 365 
THR   CA  C    sing N N 366 
THR   CA  CB   sing N N 367 
THR   CA  HA   sing N N 368 
THR   C   O    doub N N 369 
THR   C   OXT  sing N N 370 
THR   CB  OG1  sing N N 371 
THR   CB  CG2  sing N N 372 
THR   CB  HB   sing N N 373 
THR   OG1 HG1  sing N N 374 
THR   CG2 HG21 sing N N 375 
THR   CG2 HG22 sing N N 376 
THR   CG2 HG23 sing N N 377 
THR   OXT HXT  sing N N 378 
TRP   N   CA   sing N N 379 
TRP   N   H    sing N N 380 
TRP   N   H2   sing N N 381 
TRP   CA  C    sing N N 382 
TRP   CA  CB   sing N N 383 
TRP   CA  HA   sing N N 384 
TRP   C   O    doub N N 385 
TRP   C   OXT  sing N N 386 
TRP   CB  CG   sing N N 387 
TRP   CB  HB2  sing N N 388 
TRP   CB  HB3  sing N N 389 
TRP   CG  CD1  doub Y N 390 
TRP   CG  CD2  sing Y N 391 
TRP   CD1 NE1  sing Y N 392 
TRP   CD1 HD1  sing N N 393 
TRP   CD2 CE2  doub Y N 394 
TRP   CD2 CE3  sing Y N 395 
TRP   NE1 CE2  sing Y N 396 
TRP   NE1 HE1  sing N N 397 
TRP   CE2 CZ2  sing Y N 398 
TRP   CE3 CZ3  doub Y N 399 
TRP   CE3 HE3  sing N N 400 
TRP   CZ2 CH2  doub Y N 401 
TRP   CZ2 HZ2  sing N N 402 
TRP   CZ3 CH2  sing Y N 403 
TRP   CZ3 HZ3  sing N N 404 
TRP   CH2 HH2  sing N N 405 
TRP   OXT HXT  sing N N 406 
TYR   N   CA   sing N N 407 
TYR   N   H    sing N N 408 
TYR   N   H2   sing N N 409 
TYR   CA  C    sing N N 410 
TYR   CA  CB   sing N N 411 
TYR   CA  HA   sing N N 412 
TYR   C   O    doub N N 413 
TYR   C   OXT  sing N N 414 
TYR   CB  CG   sing N N 415 
TYR   CB  HB2  sing N N 416 
TYR   CB  HB3  sing N N 417 
TYR   CG  CD1  doub Y N 418 
TYR   CG  CD2  sing Y N 419 
TYR   CD1 CE1  sing Y N 420 
TYR   CD1 HD1  sing N N 421 
TYR   CD2 CE2  doub Y N 422 
TYR   CD2 HD2  sing N N 423 
TYR   CE1 CZ   doub Y N 424 
TYR   CE1 HE1  sing N N 425 
TYR   CE2 CZ   sing Y N 426 
TYR   CE2 HE2  sing N N 427 
TYR   CZ  OH   sing N N 428 
TYR   OH  HH   sing N N 429 
TYR   OXT HXT  sing N N 430 
VAL   N   CA   sing N N 431 
VAL   N   H    sing N N 432 
VAL   N   H2   sing N N 433 
VAL   CA  C    sing N N 434 
VAL   CA  CB   sing N N 435 
VAL   CA  HA   sing N N 436 
VAL   C   O    doub N N 437 
VAL   C   OXT  sing N N 438 
VAL   CB  CG1  sing N N 439 
VAL   CB  CG2  sing N N 440 
VAL   CB  HB   sing N N 441 
VAL   CG1 HG11 sing N N 442 
VAL   CG1 HG12 sing N N 443 
VAL   CG1 HG13 sing N N 444 
VAL   CG2 HG21 sing N N 445 
VAL   CG2 HG22 sing N N 446 
VAL   CG2 HG23 sing N N 447 
VAL   OXT HXT  sing N N 448 
# 
_pdbx_audit_support.funding_organization   'European Commission' 
_pdbx_audit_support.country                'European Union' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6y2e 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9F2V 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.021809 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000446 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.015702 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009663 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
F 9  9  3.5395  10.2825 2.6414 4.2944  1.5171 0.2615  1.0244 26.1476 0.3080   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0650   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N   . SER   A 1 1   ? 26.857  -19.539 23.085 1.000 20.015 0 1   SER   A N   1 ? 
ATOM   2    C CA  . SER   A 1 1   ? 26.421  -20.202 21.824 1.000 21.086 0 1   SER   A CA  1 ? 
ATOM   3    C C   . SER   A 1 1   ? 24.923  -20.006 21.668 1.000 19.016 0 1   SER   A C   1 ? 
ATOM   4    O O   . SER   A 1 1   ? 24.200  -19.994 22.665 1.000 20.055 0 1   SER   A O   1 ? 
ATOM   5    C CB  . SER   A 1 1   ? 26.796  -21.684 21.819 1.000 22.811 0 1   SER   A CB  1 ? 
ATOM   6    O OG  . SER   A 1 1   ? 26.386  -22.326 23.039 1.000 22.324 0 1   SER   A OG  1 ? 
ATOM   7    N N   . GLY   A 1 2   ? 24.469  -19.893 20.424 1.000 18.705 0 2   GLY   A N   1 ? 
ATOM   8    C CA  . GLY   A 1 2   ? 23.077  -19.594 20.130 1.000 18.189 0 2   GLY   A CA  1 ? 
ATOM   9    C C   . GLY   A 1 2   ? 22.824  -18.090 20.219 1.000 19.030 0 2   GLY   A C   1 ? 
ATOM   10   O O   . GLY   A 1 2   ? 23.590  -17.352 20.812 1.000 22.020 0 2   GLY   A O   1 ? 
ATOM   11   N N   . PHE   A 1 3   ? 21.746  -17.636 19.597 1.000 19.220 0 3   PHE   A N   1 ? 
ATOM   12   C CA  . PHE   A 1 3   ? 21.380  -16.236 19.597 1.000 19.293 0 3   PHE   A CA  1 ? 
ATOM   13   C C   . PHE   A 1 3   ? 19.860  -16.162 19.611 1.000 18.222 0 3   PHE   A C   1 ? 
ATOM   14   O O   . PHE   A 1 3   ? 19.211  -16.771 18.772 1.000 19.469 0 3   PHE   A O   1 ? 
ATOM   15   C CB  . PHE   A 1 3   ? 22.002  -15.512 18.397 1.000 18.695 0 3   PHE   A CB  1 ? 
ATOM   16   C CG  . PHE   A 1 3   ? 21.998  -14.014 18.540 1.000 18.606 0 3   PHE   A CG  1 ? 
ATOM   17   C CD1 . PHE   A 1 3   ? 22.859  -13.393 19.420 1.000 18.844 0 3   PHE   A CD1 1 ? 
ATOM   18   C CD2 . PHE   A 1 3   ? 21.057  -13.240 17.883 1.000 18.967 0 3   PHE   A CD2 1 ? 
ATOM   19   C CE1 . PHE   A 1 3   ? 22.821  -12.019 19.586 1.000 19.305 0 3   PHE   A CE1 1 ? 
ATOM   20   C CE2 . PHE   A 1 3   ? 21.012  -11.869 18.050 1.000 18.495 0 3   PHE   A CE2 1 ? 
ATOM   21   C CZ  . PHE   A 1 3   ? 21.896  -11.261 18.902 1.000 20.084 0 3   PHE   A CZ  1 ? 
ATOM   22   N N   . ARG   A 1 4   ? 19.301  -15.440 20.586 1.000 18.364 0 4   ARG   A N   1 ? 
ATOM   23   C CA  . ARG   A 1 4   ? 17.870  -15.439 20.814 1.000 19.542 0 4   ARG   A CA  1 ? 
ATOM   24   C C   . ARG   A 1 4   ? 17.399  -14.011 21.030 1.000 19.220 0 4   ARG   A C   1 ? 
ATOM   25   O O   . ARG   A 1 4   ? 18.084  -13.222 21.657 1.000 16.589 0 4   ARG   A O   1 ? 
ATOM   26   C CB  . ARG   A 1 4   ? 17.482  -16.272 22.046 1.000 20.544 0 4   ARG   A CB  1 ? 
ATOM   27   C CG  . ARG   A 1 4   ? 17.735  -17.769 21.928 1.000 24.600 0 4   ARG   A CG  1 ? 
ATOM   28   C CD  . ARG   A 1 4   ? 17.064  -18.423 20.721 1.000 27.592 0 4   ARG   A CD  1 ? 
ATOM   29   N NE  . ARG   A 1 4   ? 15.628  -18.184 20.710 1.000 27.062 0 4   ARG   A NE  1 ? 
ATOM   30   C CZ  . ARG   A 1 4   ? 14.746  -18.891 21.399 1.000 31.131 0 4   ARG   A CZ  1 ? 
ATOM   31   N NH1 . ARG   A 1 4   ? 15.121  -19.992 22.017 1.000 33.261 0 4   ARG   A NH1 1 ? 
ATOM   32   N NH2 . ARG   A 1 4   ? 13.483  -18.505 21.462 1.000 31.442 0 4   ARG   A NH2 1 ? 
ATOM   33   N N   . LYS   A 1 5   ? 16.184  -13.723 20.564 1.000 22.268 0 5   LYS   A N   1 ? 
ATOM   34   C CA  . LYS   A 1 5   ? 15.486  -12.519 20.989 1.000 24.999 0 5   LYS   A CA  1 ? 
ATOM   35   C C   . LYS   A 1 5   ? 15.176  -12.693 22.476 1.000 24.627 0 5   LYS   A C   1 ? 
ATOM   36   O O   . LYS   A 1 5   ? 14.513  -13.647 22.877 1.000 28.434 0 5   LYS   A O   1 ? 
ATOM   37   C CB  . LYS   A 1 5   ? 14.237  -12.281 20.133 1.000 26.138 0 5   LYS   A CB  1 ? 
ATOM   38   C CG  . LYS   A 1 5   ? 13.535  -10.949 20.359 1.000 29.001 0 5   LYS   A CG  1 ? 
ATOM   39   C CD  . LYS   A 1 5   ? 14.251  -9.754  19.769 1.000 31.293 0 5   LYS   A CD  1 ? 
ATOM   40   C CE  . LYS   A 1 5   ? 14.286  -9.767  18.254 1.000 33.238 0 5   LYS   A CE  1 ? 
ATOM   41   N NZ  . LYS   A 1 5   ? 12.933  -9.923  17.667 1.000 37.084 0 5   LYS   A NZ  1 ? 
ATOM   42   N N   . MET   A 1 6   ? 15.681  -11.764 23.278 1.000 22.230 0 6   MET   A N   1 ? 
ATOM   43   C CA  . MET   A 1 6   ? 15.792  -11.948 24.704 1.000 23.750 0 6   MET   A CA  1 ? 
ATOM   44   C C   . MET   A 1 6   ? 15.357  -10.657 25.412 1.000 20.539 0 6   MET   A C   1 ? 
ATOM   45   O O   . MET   A 1 6   ? 15.784  -9.568  25.045 1.000 19.132 0 6   MET   A O   1 ? 
ATOM   46   C CB  . MET   A 1 6   ? 17.251  -12.339 24.987 1.000 26.740 0 6   MET   A CB  1 ? 
ATOM   47   C CG  . MET   A 1 6   ? 17.701  -12.329 26.432 1.000 29.404 0 6   MET   A CG  1 ? 
ATOM   48   S SD  . MET   A 1 6   ? 19.400  -13.031 26.640 1.000 34.533 0 6   MET   A SD  1 ? 
ATOM   49   C CE  . MET   A 1 6   ? 19.407  -14.404 25.496 1.000 33.453 0 6   MET   A CE  1 ? 
ATOM   50   N N   . ALA   A 1 7   ? 14.479  -10.812 26.408 1.000 17.175 0 7   ALA   A N   1 ? 
ATOM   51   C CA  . ALA   A 1 7   ? 13.981  -9.721  27.222 1.000 17.914 0 7   ALA   A CA  1 ? 
ATOM   52   C C   . ALA   A 1 7   ? 14.771  -9.618  28.529 1.000 17.703 0 7   ALA   A C   1 ? 
ATOM   53   O O   . ALA   A 1 7   ? 15.397  -10.575 28.961 1.000 15.970 0 7   ALA   A O   1 ? 
ATOM   54   C CB  . ALA   A 1 7   ? 12.524  -9.988  27.509 1.000 18.700 0 7   ALA   A CB  1 ? 
ATOM   55   N N   . PHE   A 1 8   ? 14.721  -8.447  29.160 1.000 16.799 0 8   PHE   A N   1 ? 
ATOM   56   C CA  . PHE   A 1 8   ? 15.217  -8.294  30.507 1.000 17.676 0 8   PHE   A CA  1 ? 
ATOM   57   C C   . PHE   A 1 8   ? 14.390  -9.162  31.452 1.000 17.506 0 8   PHE   A C   1 ? 
ATOM   58   O O   . PHE   A 1 8   ? 13.201  -9.368  31.247 1.000 19.744 0 8   PHE   A O   1 ? 
ATOM   59   C CB  . PHE   A 1 8   ? 15.157  -6.826  30.931 1.000 17.578 0 8   PHE   A CB  1 ? 
ATOM   60   C CG  . PHE   A 1 8   ? 16.214  -6.000  30.268 1.000 18.529 0 8   PHE   A CG  1 ? 
ATOM   61   C CD1 . PHE   A 1 8   ? 17.530  -6.077  30.693 1.000 21.114 0 8   PHE   A CD1 1 ? 
ATOM   62   C CD2 . PHE   A 1 8   ? 15.904  -5.214  29.177 1.000 19.844 0 8   PHE   A CD2 1 ? 
ATOM   63   C CE1 . PHE   A 1 8   ? 18.515  -5.334  30.055 1.000 22.707 0 8   PHE   A CE1 1 ? 
ATOM   64   C CE2 . PHE   A 1 8   ? 16.894  -4.500  28.527 1.000 22.195 0 8   PHE   A CE2 1 ? 
ATOM   65   C CZ  . PHE   A 1 8   ? 18.199  -4.550  28.980 1.000 22.677 0 8   PHE   A CZ  1 ? 
ATOM   66   N N   . PRO   A 1 9   ? 14.992  -9.686  32.535 1.000 16.367 0 9   PRO   A N   1 ? 
ATOM   67   C CA  . PRO   A 1 9   ? 14.217  -10.336 33.587 1.000 17.365 0 9   PRO   A CA  1 ? 
ATOM   68   C C   . PRO   A 1 9   ? 13.270  -9.282  34.164 1.000 17.317 0 9   PRO   A C   1 ? 
ATOM   69   O O   . PRO   A 1 9   ? 13.634  -8.115  34.280 1.000 16.141 0 9   PRO   A O   1 ? 
ATOM   70   C CB  . PRO   A 1 9   ? 15.246  -10.791 34.624 1.000 17.826 0 9   PRO   A CB  1 ? 
ATOM   71   C CG  . PRO   A 1 9   ? 16.597  -10.575 33.956 1.000 18.827 0 9   PRO   A CG  1 ? 
ATOM   72   C CD  . PRO   A 1 9   ? 16.401  -9.523  32.879 1.000 17.570 0 9   PRO   A CD  1 ? 
ATOM   73   N N   . SER   A 1 10  ? 12.052  -9.689  34.497 1.000 17.285 0 10  SER   A N   1 ? 
ATOM   74   C CA  . SER   A 1 10  ? 10.985  -8.730  34.695 1.000 18.458 0 10  SER   A CA  1 ? 
ATOM   75   C C   . SER   A 1 10  ? 10.619  -8.529  36.172 1.000 16.829 0 10  SER   A C   1 ? 
ATOM   76   O O   . SER   A 1 10  ? 9.734   -7.737  36.475 1.000 15.970 0 10  SER   A O   1 ? 
ATOM   77   C CB  . SER   A 1 10  ? 9.800   -9.169  33.877 1.000 18.439 0 10  SER   A CB  1 ? 
ATOM   78   O OG  . SER   A 1 10  ? 9.412   -10.489 34.210 1.000 18.966 0 10  SER   A OG  1 ? 
ATOM   79   N N   . GLY   A 1 11  ? 11.288  -9.212  37.098 1.000 16.182 0 11  GLY   A N   1 ? 
ATOM   80   C CA  . GLY   A 1 11  ? 10.819  -9.260  38.484 1.000 17.296 0 11  GLY   A CA  1 ? 
ATOM   81   C C   . GLY   A 1 11  ? 10.664  -7.881  39.138 1.000 17.758 0 11  GLY   A C   1 ? 
ATOM   82   O O   . GLY   A 1 11  ? 9.669   -7.586  39.816 1.000 16.622 0 11  GLY   A O   1 ? 
ATOM   83   N N   . LYS   A 1 12  ? 11.642  -7.012  38.894 1.000 17.588 0 12  LYS   A N   1 ? 
ATOM   84   C CA  . LYS   A 1 12  ? 11.611  -5.666  39.430 1.000 18.486 0 12  LYS   A CA  1 ? 
ATOM   85   C C   . LYS   A 1 12  ? 10.420  -4.859  38.909 1.000 17.044 0 12  LYS   A C   1 ? 
ATOM   86   O O   . LYS   A 1 12  ? 9.984   -3.937  39.571 1.000 17.015 0 12  LYS   A O   1 ? 
ATOM   87   C CB  . LYS   A 1 12  ? 12.909  -4.961  39.065 1.000 21.767 0 12  LYS   A CB  1 ? 
ATOM   88   C CG  . LYS   A 1 12  ? 14.144  -5.405  39.835 1.000 24.877 0 12  LYS   A CG  1 ? 
ATOM   89   C CD  . LYS   A 1 12  ? 15.386  -4.863  39.189 1.000 30.149 0 12  LYS   A CD  1 ? 
ATOM   90   C CE  . LYS   A 1 12  ? 16.388  -4.295  40.174 1.000 37.489 0 12  LYS   A CE  1 ? 
ATOM   91   N NZ  . LYS   A 1 12  ? 16.972  -5.360  41.018 1.000 43.016 0 12  LYS   A NZ  1 ? 
ATOM   92   N N   . VAL   A 1 13  ? 9.880   -5.194  37.733 1.000 16.665 0 13  VAL   A N   1 ? 
ATOM   93   C CA  . VAL   A 1 13  ? 8.732   -4.463  37.220 1.000 17.908 0 13  VAL   A CA  1 ? 
ATOM   94   C C   . VAL   A 1 13  ? 7.434   -5.104  37.709 1.000 16.909 0 13  VAL   A C   1 ? 
ATOM   95   O O   . VAL   A 1 13  ? 6.473   -4.375  37.937 1.000 15.984 0 13  VAL   A O   1 ? 
ATOM   96   C CB  . VAL   A 1 13  ? 8.787   -4.324  35.686 1.000 17.668 0 13  VAL   A CB  1 ? 
ATOM   97   C CG1 . VAL   A 1 13  ? 7.544   -3.639  35.134 1.000 16.915 0 13  VAL   A CG1 1 ? 
ATOM   98   C CG2 . VAL   A 1 13  ? 10.043  -3.575  35.267 1.000 19.167 0 13  VAL   A CG2 1 ? 
ATOM   99   N N   . GLU   A 1 14  ? 7.402   -6.449  37.813 1.000 16.949 0 14  GLU   A N   1 ? 
ATOM   100  C CA  . GLU   A 1 14  ? 6.251   -7.176  38.330 1.000 18.193 0 14  GLU   A CA  1 ? 
ATOM   101  C C   . GLU   A 1 14  ? 5.828   -6.609  39.690 1.000 18.698 0 14  GLU   A C   1 ? 
ATOM   102  O O   . GLU   A 1 14  ? 4.650   -6.360  39.911 1.000 17.807 0 14  GLU   A O   1 ? 
ATOM   103  C CB  . GLU   A 1 14  ? 6.541   -8.672  38.504 1.000 19.346 0 14  GLU   A CB  1 ? 
ATOM   104  C CG  . GLU   A 1 14  ? 6.753   -9.442  37.209 1.000 21.356 0 14  GLU   A CG  1 ? 
ATOM   105  C CD  . GLU   A 1 14  ? 7.359   -10.831 37.391 1.000 22.635 0 14  GLU   A CD  1 ? 
ATOM   106  O OE1 . GLU   A 1 14  ? 6.852   -11.556 38.225 1.000 26.047 0 14  GLU   A OE1 1 ? 
ATOM   107  O OE2 . GLU   A 1 14  ? 8.312   -11.200 36.661 1.000 22.837 0 14  GLU   A OE2 1 ? 
ATOM   108  N N   . GLY   A 1 15  ? 6.807   -6.391  40.585 1.000 19.029 0 15  GLY   A N   1 ? 
ATOM   109  C CA  . GLY   A 1 15  ? 6.566   -5.811  41.894 1.000 19.564 0 15  GLY   A CA  1 ? 
ATOM   110  C C   . GLY   A 1 15  ? 5.890   -4.431  41.865 1.000 21.117 0 15  GLY   A C   1 ? 
ATOM   111  O O   . GLY   A 1 15  ? 5.451   -3.974  42.923 1.000 21.662 0 15  GLY   A O   1 ? 
ATOM   112  N N   . CYS   A 1 16  ? 5.766   -3.778  40.682 1.000 19.592 0 16  CYS   A N   1 ? 
ATOM   113  C CA  . CYS   A 1 16  ? 5.246   -2.411  40.598 1.000 19.143 0 16  CYS   A CA  1 ? 
ATOM   114  C C   . CYS   A 1 16  ? 3.899   -2.359  39.896 1.000 17.735 0 16  CYS   A C   1 ? 
ATOM   115  O O   . CYS   A 1 16  ? 3.307   -1.286  39.785 1.000 18.390 0 16  CYS   A O   1 ? 
ATOM   116  C CB  . CYS   A 1 16  ? 6.169   -1.458  39.838 1.000 18.326 0 16  CYS   A CB  1 ? 
ATOM   117  S SG  . CYS   A 1 16  ? 7.856   -1.358  40.490 1.000 19.810 0 16  CYS   A SG  1 ? 
ATOM   118  N N   . MET   A 1 17  ? 3.416   -3.497  39.411 1.000 17.069 0 17  MET   A N   1 ? 
ATOM   119  C CA  . MET   A 1 17  ? 2.173   -3.476  38.664 1.000 17.258 0 17  MET   A CA  1 ? 
ATOM   120  C C   . MET   A 1 17  ? 0.991   -3.553  39.627 1.000 16.864 0 17  MET   A C   1 ? 
ATOM   121  O O   . MET   A 1 17  ? 0.932   -4.442  40.460 1.000 15.667 0 17  MET   A O   1 ? 
ATOM   122  C CB  . MET   A 1 17  ? 2.106   -4.638  37.667 1.000 17.673 0 17  MET   A CB  1 ? 
ATOM   123  C CG  . MET   A 1 17  ? 3.224   -4.587  36.660 1.000 18.902 0 17  MET   A CG  1 ? 
ATOM   124  S SD  . MET   A 1 17  ? 3.486   -2.987  35.827 1.000 19.106 0 17  MET   A SD  1 ? 
ATOM   125  C CE  . MET   A 1 17  ? 1.829   -2.698  35.213 1.000 20.443 0 17  MET   A CE  1 ? 
ATOM   126  N N   . VAL   A 1 18  ? 0.029   -2.638  39.456 1.000 16.827 0 18  VAL   A N   1 ? 
ATOM   127  C CA  . VAL   A 1 18  ? -1.218  -2.666  40.195 1.000 16.201 0 18  VAL   A CA  1 ? 
ATOM   128  C C   . VAL   A 1 18  ? -2.380  -2.544  39.214 1.000 16.574 0 18  VAL   A C   1 ? 
ATOM   129  O O   . VAL   A 1 18  ? -2.183  -2.177  38.066 1.000 15.619 0 18  VAL   A O   1 ? 
ATOM   130  C CB  . VAL   A 1 18  ? -1.279  -1.516  41.215 1.000 15.703 0 18  VAL   A CB  1 ? 
ATOM   131  C CG1 . VAL   A 1 18  ? -0.179  -1.631  42.259 1.000 16.792 0 18  VAL   A CG1 1 ? 
ATOM   132  C CG2 . VAL   A 1 18  ? -1.224  -0.152  40.539 1.000 15.306 0 18  VAL   A CG2 1 ? 
ATOM   133  N N   . GLN   A 1 19  ? -3.596  -2.757  39.723 1.000 17.314 0 19  GLN   A N   1 ? 
ATOM   134  C CA  . GLN   A 1 19  ? -4.823  -2.591  38.957 1.000 20.010 0 19  GLN   A CA  1 ? 
ATOM   135  C C   . GLN   A 1 19  ? -5.462  -1.250  39.332 1.000 20.496 0 19  GLN   A C   1 ? 
ATOM   136  O O   . GLN   A 1 19  ? -5.563  -0.920  40.514 1.000 20.321 0 19  GLN   A O   1 ? 
ATOM   137  C CB  . GLN   A 1 19  ? -5.733  -3.796  39.238 1.000 22.248 0 19  GLN   A CB  1 ? 
ATOM   138  C CG  . GLN   A 1 19  ? -7.081  -3.735  38.539 1.000 24.918 0 19  GLN   A CG  1 ? 
ATOM   139  C CD  . GLN   A 1 19  ? -7.907  -4.964  38.823 1.000 26.899 0 19  GLN   A CD  1 ? 
ATOM   140  O OE1 . GLN   A 1 19  ? -7.999  -5.442  39.948 1.000 35.894 0 19  GLN   A OE1 1 ? 
ATOM   141  N NE2 . GLN   A 1 19  ? -8.498  -5.511  37.785 1.000 30.843 0 19  GLN   A NE2 1 ? 
ATOM   142  N N   . VAL   A 1 20  ? -5.832  -0.456  38.315 1.000 19.483 0 20  VAL   A N   1 ? 
ATOM   143  C CA  . VAL   A 1 20  ? -6.523  0.796   38.524 1.000 20.256 0 20  VAL   A CA  1 ? 
ATOM   144  C C   . VAL   A 1 20  ? -7.917  0.725   37.876 1.000 22.610 0 20  VAL   A C   1 ? 
ATOM   145  O O   . VAL   A 1 20  ? -8.050  0.474   36.675 1.000 21.311 0 20  VAL   A O   1 ? 
ATOM   146  C CB  . VAL   A 1 20  ? -5.702  1.990   37.994 1.000 19.580 0 20  VAL   A CB  1 ? 
ATOM   147  C CG1 . VAL   A 1 20  ? -6.436  3.282   38.230 1.000 18.277 0 20  VAL   A CG1 1 ? 
ATOM   148  C CG2 . VAL   A 1 20  ? -4.279  2.066   38.562 1.000 18.749 0 20  VAL   A CG2 1 ? 
ATOM   149  N N   . THR   A 1 21  ? -8.948  1.002   38.700 1.000 24.054 0 21  THR   A N   1 ? 
ATOM   150  C CA  . THR   A 1 21  ? -10.345 0.977   38.301 1.000 24.580 0 21  THR   A CA  1 ? 
ATOM   151  C C   . THR   A 1 21  ? -10.974 2.343   38.548 1.000 24.112 0 21  THR   A C   1 ? 
ATOM   152  O O   . THR   A 1 21  ? -10.877 2.918   39.627 1.000 23.975 0 21  THR   A O   1 ? 
ATOM   153  C CB  . THR   A 1 21  ? -11.134 -0.089  39.074 1.000 28.926 0 21  THR   A CB  1 ? 
ATOM   154  O OG1 . THR   A 1 21  ? -10.584 -1.375  38.772 1.000 25.296 0 21  THR   A OG1 1 ? 
ATOM   155  C CG2 . THR   A 1 21  ? -12.619 -0.071  38.759 1.000 33.321 0 21  THR   A CG2 1 ? 
ATOM   156  N N   . CYS   A 1 22  ? -11.653 2.855   37.532 1.000 26.008 0 22  CYS   A N   1 ? 
ATOM   157  C CA  . CYS   A 1 22  ? -12.412 4.078   37.674 1.000 28.657 0 22  CYS   A CA  1 ? 
ATOM   158  C C   . CYS   A 1 22  ? -13.765 3.838   37.017 1.000 31.787 0 22  CYS   A C   1 ? 
ATOM   159  O O   . CYS   A 1 22  ? -13.849 3.672   35.804 1.000 28.272 0 22  CYS   A O   1 ? 
ATOM   160  C CB  . CYS   A 1 22  ? -11.646 5.234   37.049 1.000 29.586 0 22  CYS   A CB  1 ? 
ATOM   161  S SG  . CYS   A 1 22  ? -12.438 6.840   37.296 1.000 38.116 0 22  CYS   A SG  1 ? 
ATOM   162  N N   . GLY   A 1 23  ? -14.804 3.755   37.846 1.000 34.402 0 23  GLY   A N   1 ? 
ATOM   163  C CA  . GLY   A 1 23  ? -16.119 3.344   37.390 1.000 33.951 0 23  GLY   A CA  1 ? 
ATOM   164  C C   . GLY   A 1 23  ? -16.091 1.917   36.858 1.000 32.624 0 23  GLY   A C   1 ? 
ATOM   165  O O   . GLY   A 1 23  ? -15.890 0.974   37.607 1.000 32.669 0 23  GLY   A O   1 ? 
ATOM   166  N N   . THR   A 1 24  ? -16.218 1.812   35.534 1.000 39.466 0 24  THR   A N   1 ? 
ATOM   167  C CA  . THR   A 1 24  ? -16.407 0.563   34.822 1.000 38.565 0 24  THR   A CA  1 ? 
ATOM   168  C C   . THR   A 1 24  ? -15.177 0.222   33.973 1.000 35.709 0 24  THR   A C   1 ? 
ATOM   169  O O   . THR   A 1 24  ? -15.176 -0.764  33.249 1.000 36.341 0 24  THR   A O   1 ? 
ATOM   170  C CB  . THR   A 1 24  ? -17.653 0.693   33.937 1.000 41.647 0 24  THR   A CB  1 ? 
ATOM   171  O OG1 . THR   A 1 24  ? -17.813 -0.566  33.293 1.000 46.391 0 24  THR   A OG1 1 ? 
ATOM   172  C CG2 . THR   A 1 24  ? -17.567 1.789   32.893 1.000 41.494 0 24  THR   A CG2 1 ? 
ATOM   173  N N   . THR   A 1 25  ? -14.143 1.064   34.015 1.000 32.920 0 25  THR   A N   1 ? 
ATOM   174  C CA  . THR   A 1 25  ? -12.945 0.858   33.212 1.000 30.566 0 25  THR   A CA  1 ? 
ATOM   175  C C   . THR   A 1 25  ? -11.815 0.342   34.096 1.000 25.887 0 25  THR   A C   1 ? 
ATOM   176  O O   . THR   A 1 25  ? -11.434 1.008   35.052 1.000 24.518 0 25  THR   A O   1 ? 
ATOM   177  C CB  . THR   A 1 25  ? -12.462 2.176   32.593 1.000 33.209 0 25  THR   A CB  1 ? 
ATOM   178  O OG1 . THR   A 1 25  ? -13.606 2.846   32.081 1.000 34.315 0 25  THR   A OG1 1 ? 
ATOM   179  C CG2 . THR   A 1 25  ? -11.421 1.988   31.508 1.000 34.493 0 25  THR   A CG2 1 ? 
ATOM   180  N N   . THR   A 1 26  ? -11.262 -0.825  33.776 1.000 22.987 0 26  THR   A N   1 ? 
ATOM   181  C CA  . THR   A 1 26  ? -10.077 -1.268  34.477 1.000 24.954 0 26  THR   A CA  1 ? 
ATOM   182  C C   . THR   A 1 26  ? -8.873  -1.404  33.545 1.000 24.306 0 26  THR   A C   1 ? 
ATOM   183  O O   . THR   A 1 26  ? -8.980  -1.875  32.407 1.000 21.976 0 26  THR   A O   1 ? 
ATOM   184  C CB  . THR   A 1 26  ? -10.297 -2.587  35.210 1.000 27.899 0 26  THR   A CB  1 ? 
ATOM   185  O OG1 . THR   A 1 26  ? -11.475 -2.522  36.015 1.000 33.004 0 26  THR   A OG1 1 ? 
ATOM   186  C CG2 . THR   A 1 26  ? -9.134  -2.891  36.125 1.000 29.868 0 26  THR   A CG2 1 ? 
ATOM   187  N N   . LEU   A 1 27  ? -7.700  -1.024  34.079 1.000 20.887 0 27  LEU   A N   1 ? 
ATOM   188  C CA  . LEU   A 1 27  ? -6.441  -1.236  33.379 1.000 18.637 0 27  LEU   A CA  1 ? 
ATOM   189  C C   . LEU   A 1 27  ? -5.292  -1.257  34.395 1.000 17.764 0 27  LEU   A C   1 ? 
ATOM   190  O O   . LEU   A 1 27  ? -5.537  -1.352  35.598 1.000 16.730 0 27  LEU   A O   1 ? 
ATOM   191  C CB  . LEU   A 1 27  ? -6.282  -0.163  32.301 1.000 18.555 0 27  LEU   A CB  1 ? 
ATOM   192  C CG  . LEU   A 1 27  ? -6.607  1.276   32.704 1.000 19.033 0 27  LEU   A CG  1 ? 
ATOM   193  C CD1 . LEU   A 1 27  ? -5.685  1.781   33.794 1.000 17.791 0 27  LEU   A CD1 1 ? 
ATOM   194  C CD2 . LEU   A 1 27  ? -6.540  2.200   31.486 1.000 20.368 0 27  LEU   A CD2 1 ? 
ATOM   195  N N   . ASN   A 1 28  ? -4.047  -1.215  33.911 1.000 15.023 0 28  ASN   A N   1 ? 
ATOM   196  C CA  . ASN   A 1 28  ? -2.900  -1.432  34.775 1.000 15.114 0 28  ASN   A CA  1 ? 
ATOM   197  C C   . ASN   A 1 28  ? -2.300  -0.084  35.177 1.000 14.960 0 28  ASN   A C   1 ? 
ATOM   198  O O   . ASN   A 1 28  ? -2.383  0.877   34.418 1.000 16.163 0 28  ASN   A O   1 ? 
ATOM   199  C CB  . ASN   A 1 28  ? -1.859  -2.327  34.094 1.000 14.864 0 28  ASN   A CB  1 ? 
ATOM   200  C CG  . ASN   A 1 28  ? -2.425  -3.632  33.560 1.000 14.813 0 28  ASN   A CG  1 ? 
ATOM   201  O OD1 . ASN   A 1 28  ? -2.648  -4.593  34.295 1.000 16.517 0 28  ASN   A OD1 1 ? 
ATOM   202  N ND2 . ASN   A 1 28  ? -2.576  -3.710  32.260 1.000 14.190 0 28  ASN   A ND2 1 ? 
ATOM   203  N N   . GLY   A 1 29  ? -1.672  -0.038  36.358 1.000 14.961 0 29  GLY   A N   1 ? 
ATOM   204  C CA  . GLY   A 1 29  ? -0.911  1.116   36.804 1.000 14.146 0 29  GLY   A CA  1 ? 
ATOM   205  C C   . GLY   A 1 29  ? 0.476   0.709   37.278 1.000 14.320 0 29  GLY   A C   1 ? 
ATOM   206  O O   . GLY   A 1 29  ? 0.714   -0.446  37.611 1.000 15.262 0 29  GLY   A O   1 ? 
ATOM   207  N N   . LEU   A 1 30  ? 1.406   1.658   37.227 1.000 14.716 0 30  LEU   A N   1 ? 
ATOM   208  C CA  . LEU   A 1 30  ? 2.753   1.446   37.720 1.000 15.928 0 30  LEU   A CA  1 ? 
ATOM   209  C C   . LEU   A 1 30  ? 2.929   2.146   39.076 1.000 15.963 0 30  LEU   A C   1 ? 
ATOM   210  O O   . LEU   A 1 30  ? 2.820   3.355   39.166 1.000 15.031 0 30  LEU   A O   1 ? 
ATOM   211  C CB  . LEU   A 1 30  ? 3.716   1.986   36.661 1.000 15.616 0 30  LEU   A CB  1 ? 
ATOM   212  C CG  . LEU   A 1 30  ? 5.210   1.785   36.920 1.000 17.414 0 30  LEU   A CG  1 ? 
ATOM   213  C CD1 . LEU   A 1 30  ? 5.585   0.316   36.864 1.000 18.220 0 30  LEU   A CD1 1 ? 
ATOM   214  C CD2 . LEU   A 1 30  ? 6.051   2.572   35.923 1.000 17.643 0 30  LEU   A CD2 1 ? 
ATOM   215  N N   . TRP   A 1 31  ? 3.235   1.382   40.126 1.000 17.165 0 31  TRP   A N   1 ? 
ATOM   216  C CA  . TRP   A 1 31  ? 3.332   1.920   41.479 1.000 16.612 0 31  TRP   A CA  1 ? 
ATOM   217  C C   . TRP   A 1 31  ? 4.798   2.075   41.868 1.000 15.931 0 31  TRP   A C   1 ? 
ATOM   218  O O   . TRP   A 1 31  ? 5.483   1.085   42.117 1.000 14.710 0 31  TRP   A O   1 ? 
ATOM   219  C CB  . TRP   A 1 31  ? 2.578   1.003   42.451 1.000 18.088 0 31  TRP   A CB  1 ? 
ATOM   220  C CG  . TRP   A 1 31  ? 2.513   1.405   43.906 1.000 18.671 0 31  TRP   A CG  1 ? 
ATOM   221  C CD1 . TRP   A 1 31  ? 2.621   2.633   44.489 1.000 19.371 0 31  TRP   A CD1 1 ? 
ATOM   222  C CD2 . TRP   A 1 31  ? 2.312   0.473   44.988 1.000 21.378 0 31  TRP   A CD2 1 ? 
ATOM   223  N NE1 . TRP   A 1 31  ? 2.456   2.544   45.847 1.000 19.451 0 31  TRP   A NE1 1 ? 
ATOM   224  C CE2 . TRP   A 1 31  ? 2.290   1.224   46.186 1.000 21.495 0 31  TRP   A CE2 1 ? 
ATOM   225  C CE3 . TRP   A 1 31  ? 2.158   -0.919  45.053 1.000 23.374 0 31  TRP   A CE3 1 ? 
ATOM   226  C CZ2 . TRP   A 1 31  ? 2.123   0.614   47.427 1.000 21.724 0 31  TRP   A CZ2 1 ? 
ATOM   227  C CZ3 . TRP   A 1 31  ? 2.004   -1.523  46.285 1.000 23.489 0 31  TRP   A CZ3 1 ? 
ATOM   228  C CH2 . TRP   A 1 31  ? 1.981   -0.758  47.455 1.000 23.535 0 31  TRP   A CH2 1 ? 
ATOM   229  N N   . LEU   A 1 32  ? 5.250   3.327   41.903 1.000 14.588 0 32  LEU   A N   1 ? 
ATOM   230  C CA  . LEU   A 1 32  ? 6.619   3.662   42.259 1.000 16.629 0 32  LEU   A CA  1 ? 
ATOM   231  C C   . LEU   A 1 32  ? 6.559   4.685   43.387 1.000 16.737 0 32  LEU   A C   1 ? 
ATOM   232  O O   . LEU   A 1 32  ? 5.848   5.680   43.255 1.000 13.897 0 32  LEU   A O   1 ? 
ATOM   233  C CB  . LEU   A 1 32  ? 7.342   4.257   41.050 1.000 17.233 0 32  LEU   A CB  1 ? 
ATOM   234  C CG  . LEU   A 1 32  ? 7.438   3.375   39.801 1.000 18.371 0 32  LEU   A CG  1 ? 
ATOM   235  C CD1 . LEU   A 1 32  ? 7.848   4.191   38.579 1.000 18.423 0 32  LEU   A CD1 1 ? 
ATOM   236  C CD2 . LEU   A 1 32  ? 8.414   2.245   40.007 1.000 18.572 0 32  LEU   A CD2 1 ? 
ATOM   237  N N   . ASP   A 1 33  ? 7.245   4.394   44.507 1.000 17.383 0 33  ASP   A N   1 ? 
ATOM   238  C CA  . ASP   A 1 33  ? 7.119   5.222   45.694 1.000 18.843 0 33  ASP   A CA  1 ? 
ATOM   239  C C   . ASP   A 1 33  ? 5.624   5.326   46.015 1.000 18.547 0 33  ASP   A C   1 ? 
ATOM   240  O O   . ASP   A 1 33  ? 4.920   4.305   45.982 1.000 19.639 0 33  ASP   A O   1 ? 
ATOM   241  C CB  . ASP   A 1 33  ? 7.873   6.544   45.510 1.000 19.952 0 33  ASP   A CB  1 ? 
ATOM   242  C CG  . ASP   A 1 33  ? 9.358   6.367   45.200 1.000 23.892 0 33  ASP   A CG  1 ? 
ATOM   243  O OD1 . ASP   A 1 33  ? 9.952   5.439   45.758 1.000 25.557 0 33  ASP   A OD1 1 ? 
ATOM   244  O OD2 . ASP   A 1 33  ? 9.918   7.170   44.417 1.000 28.488 0 33  ASP   A OD2 1 ? 
ATOM   245  N N   . ASP   A 1 34  ? 5.138   6.540   46.301 1.000 17.654 0 34  ASP   A N   1 ? 
ATOM   246  C CA  . ASP   A 1 34  ? 3.745   6.739   46.668 1.000 19.208 0 34  ASP   A CA  1 ? 
ATOM   247  C C   . ASP   A 1 34  ? 2.922   7.263   45.488 1.000 17.897 0 34  ASP   A C   1 ? 
ATOM   248  O O   . ASP   A 1 34  ? 1.863   7.841   45.713 1.000 16.580 0 34  ASP   A O   1 ? 
ATOM   249  C CB  . ASP   A 1 34  ? 3.596   7.683   47.866 1.000 20.637 0 34  ASP   A CB  1 ? 
ATOM   250  C CG  . ASP   A 1 34  ? 4.217   9.065   47.704 1.000 22.138 0 34  ASP   A CG  1 ? 
ATOM   251  O OD1 . ASP   A 1 34  ? 4.932   9.297   46.713 1.000 22.217 0 34  ASP   A OD1 1 ? 
ATOM   252  O OD2 . ASP   A 1 34  ? 4.014   9.889   48.599 1.000 24.508 0 34  ASP   A OD2 1 ? 
ATOM   253  N N   . VAL   A 1 35  ? 3.362   6.990   44.249 1.000 17.371 0 35  VAL   A N   1 ? 
ATOM   254  C CA  . VAL   A 1 35  ? 2.590   7.352   43.068 1.000 18.099 0 35  VAL   A CA  1 ? 
ATOM   255  C C   . VAL   A 1 35  ? 2.235   6.144   42.203 1.000 18.109 0 35  VAL   A C   1 ? 
ATOM   256  O O   . VAL   A 1 35  ? 3.045   5.240   41.974 1.000 18.771 0 35  VAL   A O   1 ? 
ATOM   257  C CB  . VAL   A 1 35  ? 3.328   8.401   42.231 1.000 17.802 0 35  VAL   A CB  1 ? 
ATOM   258  C CG1 . VAL   A 1 35  ? 2.417   8.924   41.137 1.000 18.683 0 35  VAL   A CG1 1 ? 
ATOM   259  C CG2 . VAL   A 1 35  ? 3.813   9.561   43.091 1.000 20.152 0 35  VAL   A CG2 1 ? 
ATOM   260  N N   . VAL   A 1 36  ? 1.007   6.163   41.684 1.000 17.557 0 36  VAL   A N   1 ? 
ATOM   261  C CA  . VAL   A 1 36  ? 0.601   5.217   40.665 1.000 16.394 0 36  VAL   A CA  1 ? 
ATOM   262  C C   . VAL   A 1 36  ? 0.377   5.984   39.356 1.000 16.789 0 36  VAL   A C   1 ? 
ATOM   263  O O   . VAL   A 1 36  ? -0.385  6.952   39.319 1.000 16.571 0 36  VAL   A O   1 ? 
ATOM   264  C CB  . VAL   A 1 36  ? -0.621  4.392   41.113 1.000 16.241 0 36  VAL   A CB  1 ? 
ATOM   265  C CG1 . VAL   A 1 36  ? -1.124  3.469   40.010 1.000 15.706 0 36  VAL   A CG1 1 ? 
ATOM   266  C CG2 . VAL   A 1 36  ? -0.285  3.565   42.344 1.000 16.505 0 36  VAL   A CG2 1 ? 
ATOM   267  N N   . TYR   A 1 37  ? 1.083   5.540   38.302 1.000 14.853 0 37  TYR   A N   1 ? 
ATOM   268  C CA  . TYR   A 1 37  ? 0.969   6.092   36.968 1.000 14.445 0 37  TYR   A CA  1 ? 
ATOM   269  C C   . TYR   A 1 37  ? 0.072   5.185   36.116 1.000 13.839 0 37  TYR   A C   1 ? 
ATOM   270  O O   . TYR   A 1 37  ? 0.191   3.959   36.149 1.000 14.799 0 37  TYR   A O   1 ? 
ATOM   271  C CB  . TYR   A 1 37  ? 2.370   6.248   36.358 1.000 14.410 0 37  TYR   A CB  1 ? 
ATOM   272  C CG  . TYR   A 1 37  ? 3.377   7.026   37.191 1.000 14.111 0 37  TYR   A CG  1 ? 
ATOM   273  C CD1 . TYR   A 1 37  ? 4.009   6.429   38.278 1.000 14.497 0 37  TYR   A CD1 1 ? 
ATOM   274  C CD2 . TYR   A 1 37  ? 3.660   8.365   36.924 1.000 13.910 0 37  TYR   A CD2 1 ? 
ATOM   275  C CE1 . TYR   A 1 37  ? 4.912   7.128   39.065 1.000 14.951 0 37  TYR   A CE1 1 ? 
ATOM   276  C CE2 . TYR   A 1 37  ? 4.564   9.072   37.696 1.000 13.819 0 37  TYR   A CE2 1 ? 
ATOM   277  C CZ  . TYR   A 1 37  ? 5.186   8.445   38.763 1.000 14.845 0 37  TYR   A CZ  1 ? 
ATOM   278  O OH  . TYR   A 1 37  ? 6.048   9.115   39.553 1.000 17.639 0 37  TYR   A OH  1 ? 
ATOM   279  N N   . CYS   A 1 38  ? -0.823  5.779   35.325 1.000 13.356 0 38  CYS   A N   1 ? 
ATOM   280  C CA  . CYS   A 1 38  ? -1.593  5.007   34.374 1.000 13.779 0 38  CYS   A CA  1 ? 
ATOM   281  C C   . CYS   A 1 38  ? -2.088  5.894   33.243 1.000 13.982 0 38  CYS   A C   1 ? 
ATOM   282  O O   . CYS   A 1 38  ? -2.032  7.117   33.361 1.000 14.371 0 38  CYS   A O   1 ? 
ATOM   283  C CB  . CYS   A 1 38  ? -2.746  4.302   35.068 1.000 16.659 0 38  CYS   A CB  1 ? 
ATOM   284  S SG  . CYS   A 1 38  ? -4.063  5.390   35.672 1.000 21.584 0 38  CYS   A SG  1 ? 
ATOM   285  N N   . PRO   A 1 39  ? -2.594  5.325   32.116 1.000 14.026 0 39  PRO   A N   1 ? 
ATOM   286  C CA  . PRO   A 1 39  ? -3.182  6.133   31.048 1.000 14.643 0 39  PRO   A CA  1 ? 
ATOM   287  C C   . PRO   A 1 39  ? -4.393  6.909   31.548 1.000 14.355 0 39  PRO   A C   1 ? 
ATOM   288  O O   . PRO   A 1 39  ? -5.191  6.391   32.322 1.000 13.477 0 39  PRO   A O   1 ? 
ATOM   289  C CB  . PRO   A 1 39  ? -3.607  5.117   29.973 1.000 14.362 0 39  PRO   A CB  1 ? 
ATOM   290  C CG  . PRO   A 1 39  ? -2.695  3.939   30.251 1.000 14.588 0 39  PRO   A CG  1 ? 
ATOM   291  C CD  . PRO   A 1 39  ? -2.600  3.895   31.767 1.000 14.269 0 39  PRO   A CD  1 ? 
ATOM   292  N N   . ARG   A 1 40  ? -4.527  8.151   31.068 1.000 14.784 0 40  ARG   A N   1 ? 
ATOM   293  C CA  . ARG   A 1 40  ? -5.557  9.037   31.584 1.000 14.626 0 40  ARG   A CA  1 ? 
ATOM   294  C C   . ARG   A 1 40  ? -6.940  8.575   31.135 1.000 15.074 0 40  ARG   A C   1 ? 
ATOM   295  O O   . ARG   A 1 40  ? -7.932  8.989   31.737 1.000 14.053 0 40  ARG   A O   1 ? 
ATOM   296  C CB  . ARG   A 1 40  ? -5.271  10.479  31.171 1.000 15.318 0 40  ARG   A CB  1 ? 
ATOM   297  C CG  . ARG   A 1 40  ? -5.432  10.751  29.683 1.000 15.602 0 40  ARG   A CG  1 ? 
ATOM   298  C CD  . ARG   A 1 40  ? -5.080  12.195  29.438 1.000 16.682 0 40  ARG   A CD  1 ? 
ATOM   299  N NE  . ARG   A 1 40  ? -5.065  12.522  28.031 1.000 16.612 0 40  ARG   A NE  1 ? 
ATOM   300  C CZ  . ARG   A 1 40  ? -4.990  13.755  27.550 1.000 19.456 0 40  ARG   A CZ  1 ? 
ATOM   301  N NH1 . ARG   A 1 40  ? -4.806  14.769  28.382 1.000 19.655 0 40  ARG   A NH1 1 ? 
ATOM   302  N NH2 . ARG   A 1 40  ? -5.108  13.958  26.242 1.000 18.782 0 40  ARG   A NH2 1 ? 
ATOM   303  N N   . HIS   A 1 41  ? -7.025  7.715   30.101 1.000 14.945 0 41  HIS   A N   1 ? 
ATOM   304  C CA  . HIS   A 1 41  ? -8.325  7.333   29.574 1.000 16.146 0 41  HIS   A CA  1 ? 
ATOM   305  C C   . HIS   A 1 41  ? -9.027  6.327   30.493 1.000 16.332 0 41  HIS   A C   1 ? 
ATOM   306  O O   . HIS   A 1 41  ? -10.158 5.928   30.223 1.000 16.454 0 41  HIS   A O   1 ? 
ATOM   307  C CB  . HIS   A 1 41  ? -8.255  6.894   28.101 1.000 16.350 0 41  HIS   A CB  1 ? 
ATOM   308  C CG  . HIS   A 1 41  ? -7.590  5.580   27.877 1.000 15.643 0 41  HIS   A CG  1 ? 
ATOM   309  N ND1 . HIS   A 1 41  ? -6.261  5.518   27.531 1.000 14.766 0 41  HIS   A ND1 1 ? 
ATOM   310  C CD2 . HIS   A 1 41  ? -8.018  4.302   27.963 1.000 16.579 0 41  HIS   A CD2 1 ? 
ATOM   311  C CE1 . HIS   A 1 41  ? -5.919  4.242   27.389 1.000 15.306 0 41  HIS   A CE1 1 ? 
ATOM   312  N NE2 . HIS   A 1 41  ? -6.951  3.487   27.675 1.000 15.042 0 41  HIS   A NE2 1 ? 
ATOM   313  N N   . VAL   A 1 42  ? -8.433  6.015   31.644 1.000 17.443 0 42  VAL   A N   1 ? 
ATOM   314  C CA  . VAL   A 1 42  ? -9.129  5.224   32.647 1.000 17.998 0 42  VAL   A CA  1 ? 
ATOM   315  C C   . VAL   A 1 42  ? -10.347 5.984   33.189 1.000 19.338 0 42  VAL   A C   1 ? 
ATOM   316  O O   . VAL   A 1 42  ? -11.239 5.357   33.752 1.000 17.152 0 42  VAL   A O   1 ? 
ATOM   317  C CB  . VAL   A 1 42  ? -8.189  4.783   33.783 1.000 17.678 0 42  VAL   A CB  1 ? 
ATOM   318  C CG1 . VAL   A 1 42  ? -7.772  5.919   34.696 1.000 18.163 0 42  VAL   A CG1 1 ? 
ATOM   319  C CG2 . VAL   A 1 42  ? -8.805  3.672   34.611 1.000 18.868 0 42  VAL   A CG2 1 ? 
ATOM   320  N N   . ILE   A 1 43  ? -10.405 7.311   33.002 1.000 18.830 0 43  ILE   A N   1 ? 
ATOM   321  C CA  . ILE   A 1 43  ? -11.522 8.110   33.508 1.000 22.185 0 43  ILE   A CA  1 ? 
ATOM   322  C C   . ILE   A 1 43  ? -12.661 8.269   32.482 1.000 24.970 0 43  ILE   A C   1 ? 
ATOM   323  O O   . ILE   A 1 43  ? -13.626 8.961   32.780 1.000 27.481 0 43  ILE   A O   1 ? 
ATOM   324  C CB  . ILE   A 1 43  ? -11.032 9.501   33.980 1.000 18.726 0 43  ILE   A CB  1 ? 
ATOM   325  C CG1 . ILE   A 1 43  ? -10.752 10.429  32.800 1.000 17.387 0 43  ILE   A CG1 1 ? 
ATOM   326  C CG2 . ILE   A 1 43  ? -9.833  9.377   34.893 1.000 19.964 0 43  ILE   A CG2 1 ? 
ATOM   327  C CD1 . ILE   A 1 43  ? -10.169 11.738  33.167 1.000 17.897 0 43  ILE   A CD1 1 ? 
ATOM   328  N N   . CYS   A 1 44  ? -12.559 7.689   31.276 1.000 29.743 0 44  CYS   A N   1 ? 
ATOM   329  C CA  . CYS   A 1 44  ? -13.619 7.812   30.282 1.000 33.018 0 44  CYS   A CA  1 ? 
ATOM   330  C C   . CYS   A 1 44  ? -14.556 6.604   30.297 1.000 37.799 0 44  CYS   A C   1 ? 
ATOM   331  O O   . CYS   A 1 44  ? -14.139 5.473   30.528 1.000 41.235 0 44  CYS   A O   1 ? 
ATOM   332  C CB  . CYS   A 1 44  ? -13.075 7.899   28.867 1.000 33.822 0 44  CYS   A CB  1 ? 
ATOM   333  S SG  . CYS   A 1 44  ? -11.773 9.132   28.642 1.000 36.363 0 44  CYS   A SG  1 ? 
ATOM   334  N N   . THR   A 1 45  ? -15.831 6.871   30.030 1.000 40.648 0 45  THR   A N   1 ? 
ATOM   335  C CA  . THR   A 1 45  ? -16.786 5.847   29.652 1.000 45.131 0 45  THR   A CA  1 ? 
ATOM   336  C C   . THR   A 1 45  ? -16.662 5.675   28.142 1.000 45.576 0 45  THR   A C   1 ? 
ATOM   337  O O   . THR   A 1 45  ? -16.066 6.526   27.479 1.000 42.948 0 45  THR   A O   1 ? 
ATOM   338  C CB  . THR   A 1 45  ? -18.202 6.253   30.091 1.000 45.761 0 45  THR   A CB  1 ? 
ATOM   339  O OG1 . THR   A 1 45  ? -18.585 7.386   29.319 1.000 48.685 0 45  THR   A OG1 1 ? 
ATOM   340  C CG2 . THR   A 1 45  ? -18.308 6.623   31.556 1.000 46.649 0 45  THR   A CG2 1 ? 
ATOM   341  N N   . SER   A 1 46  ? -17.241 4.598   27.600 1.000 48.774 0 46  SER   A N   1 ? 
ATOM   342  C CA  . SER   A 1 46  ? -17.192 4.350   26.166 1.000 49.085 0 46  SER   A CA  1 ? 
ATOM   343  C C   . SER   A 1 46  ? -17.745 5.547   25.382 1.000 49.149 0 46  SER   A C   1 ? 
ATOM   344  O O   . SER   A 1 46  ? -17.197 5.908   24.339 1.000 42.268 0 46  SER   A O   1 ? 
ATOM   345  C CB  . SER   A 1 46  ? -17.879 3.052   25.808 1.000 49.471 0 46  SER   A CB  1 ? 
ATOM   346  O OG  . SER   A 1 46  ? -19.125 2.919   26.470 1.000 50.097 0 46  SER   A OG  1 ? 
ATOM   347  N N   . GLU   A 1 47  ? -18.775 6.209   25.930 1.000 50.060 0 47  GLU   A N   1 ? 
ATOM   348  C CA  . GLU   A 1 47  ? -19.444 7.313   25.251 1.000 51.573 0 47  GLU   A CA  1 ? 
ATOM   349  C C   . GLU   A 1 47  ? -18.632 8.614   25.283 1.000 46.098 0 47  GLU   A C   1 ? 
ATOM   350  O O   . GLU   A 1 47  ? -19.005 9.562   24.608 1.000 51.544 0 47  GLU   A O   1 ? 
ATOM   351  C CB  . GLU   A 1 47  ? -20.843 7.511   25.846 1.000 59.700 0 47  GLU   A CB  1 ? 
ATOM   352  C CG  . GLU   A 1 47  ? -20.847 8.019   27.280 1.000 67.501 0 47  GLU   A CG  1 ? 
ATOM   353  C CD  . GLU   A 1 47  ? -22.077 7.654   28.098 1.000 69.896 0 47  GLU   A CD  1 ? 
ATOM   354  O OE1 . GLU   A 1 47  ? -21.930 7.389   29.319 1.000 62.562 0 47  GLU   A OE1 1 ? 
ATOM   355  O OE2 . GLU   A 1 47  ? -23.179 7.623   27.508 1.000 69.814 0 47  GLU   A OE2 1 ? 
ATOM   356  N N   . ASP   A 1 48  ? -17.530 8.687   26.037 1.000 43.810 0 48  ASP   A N   1 ? 
ATOM   357  C CA  . ASP   A 1 48  ? -16.672 9.872   26.033 1.000 45.622 0 48  ASP   A CA  1 ? 
ATOM   358  C C   . ASP   A 1 48  ? -15.496 9.724   25.061 1.000 41.011 0 48  ASP   A C   1 ? 
ATOM   359  O O   . ASP   A 1 48  ? -14.812 10.704  24.771 1.000 37.101 0 48  ASP   A O   1 ? 
ATOM   360  C CB  . ASP   A 1 48  ? -16.005 10.154  27.388 1.000 45.324 0 48  ASP   A CB  1 ? 
ATOM   361  C CG  . ASP   A 1 48  ? -16.927 10.420  28.569 1.000 48.962 0 48  ASP   A CG  1 ? 
ATOM   362  O OD1 . ASP   A 1 48  ? -17.739 11.388  28.485 1.000 45.734 0 48  ASP   A OD1 1 ? 
ATOM   363  O OD2 . ASP   A 1 48  ? -16.790 9.684   29.591 1.000 43.519 0 48  ASP   A OD2 1 ? 
ATOM   364  N N   . MET   A 1 49  ? -15.235 8.497   24.596 1.000 37.684 0 49  MET   A N   1 ? 
ATOM   365  C CA  . MET   A 1 49  ? -13.934 8.155   24.039 1.000 36.965 0 49  MET   A CA  1 ? 
ATOM   366  C C   . MET   A 1 49  ? -13.735 8.792   22.664 1.000 33.900 0 49  MET   A C   1 ? 
ATOM   367  O O   . MET   A 1 49  ? -12.596 9.022   22.249 1.000 27.677 0 49  MET   A O   1 ? 
ATOM   368  C CB  . MET   A 1 49  ? -13.774 6.638   23.915 1.000 39.613 0 49  MET   A CB  1 ? 
ATOM   369  C CG  . MET   A 1 49  ? -13.434 5.958   25.227 1.000 46.794 0 49  MET   A CG  1 ? 
ATOM   370  S SD  . MET   A 1 49  ? -11.924 6.589   26.026 1.000 50.418 0 49  MET   A SD  1 ? 
ATOM   371  C CE  . MET   A 1 49  ? -10.833 6.744   24.619 1.000 45.805 0 49  MET   A CE  1 ? 
ATOM   372  N N   . LEU   A 1 50  ? -14.843 9.087   21.975 1.000 33.435 0 50  LEU   A N   1 ? 
ATOM   373  C CA  . LEU   A 1 50  ? -14.773 9.636   20.630 1.000 37.062 0 50  LEU   A CA  1 ? 
ATOM   374  C C   . LEU   A 1 50  ? -14.107 11.012  20.640 1.000 37.955 0 50  LEU   A C   1 ? 
ATOM   375  O O   . LEU   A 1 50  ? -13.311 11.312  19.750 1.000 36.821 0 50  LEU   A O   1 ? 
ATOM   376  C CB  . LEU   A 1 50  ? -16.174 9.655   20.013 1.000 40.857 0 50  LEU   A CB  1 ? 
ATOM   377  C CG  . LEU   A 1 50  ? -16.489 8.435   19.139 1.000 42.732 0 50  LEU   A CG  1 ? 
ATOM   378  C CD1 . LEU   A 1 50  ? -16.443 7.157   19.939 1.000 46.214 0 50  LEU   A CD1 1 ? 
ATOM   379  C CD2 . LEU   A 1 50  ? -17.844 8.570   18.478 1.000 48.059 0 50  LEU   A CD2 1 ? 
ATOM   380  N N   . ASN   A 1 51  ? -14.366 11.826  21.671 1.000 34.466 0 51  ASN   A N   1 ? 
ATOM   381  C CA  . ASN   A 1 51  ? -13.775 13.151  21.689 1.000 35.160 0 51  ASN   A CA  1 ? 
ATOM   382  C C   . ASN   A 1 51  ? -13.702 13.655  23.131 1.000 34.897 0 51  ASN   A C   1 ? 
ATOM   383  O O   . ASN   A 1 51  ? -14.299 14.666  23.476 1.000 33.522 0 51  ASN   A O   1 ? 
ATOM   384  C CB  . ASN   A 1 51  ? -14.552 14.038  20.717 1.000 38.697 0 51  ASN   A CB  1 ? 
ATOM   385  C CG  . ASN   A 1 51  ? -14.146 15.489  20.785 1.000 42.654 0 51  ASN   A CG  1 ? 
ATOM   386  O OD1 . ASN   A 1 51  ? -12.961 15.811  20.711 1.000 41.503 0 51  ASN   A OD1 1 ? 
ATOM   387  N ND2 . ASN   A 1 51  ? -15.128 16.355  20.963 1.000 44.095 0 51  ASN   A ND2 1 ? 
ATOM   388  N N   . PRO   A 1 52  ? -12.941 12.987  24.028 1.000 35.498 0 52  PRO   A N   1 ? 
ATOM   389  C CA  . PRO   A 1 52  ? -13.031 13.264  25.460 1.000 33.622 0 52  PRO   A CA  1 ? 
ATOM   390  C C   . PRO   A 1 52  ? -12.402 14.614  25.763 1.000 30.119 0 52  PRO   A C   1 ? 
ATOM   391  O O   . PRO   A 1 52  ? -11.454 15.022  25.098 1.000 27.585 0 52  PRO   A O   1 ? 
ATOM   392  C CB  . PRO   A 1 52  ? -12.218 12.127  26.107 1.000 35.286 0 52  PRO   A CB  1 ? 
ATOM   393  C CG  . PRO   A 1 52  ? -11.180 11.790  25.050 1.000 35.532 0 52  PRO   A CG  1 ? 
ATOM   394  C CD  . PRO   A 1 52  ? -11.883 12.011  23.718 1.000 34.493 0 52  PRO   A CD  1 ? 
ATOM   395  N N   . ASN   A 1 53  ? -12.992 15.327  26.720 1.000 30.521 0 53  ASN   A N   1 ? 
ATOM   396  C CA  . ASN   A 1 53  ? -12.337 16.472  27.328 1.000 31.673 0 53  ASN   A CA  1 ? 
ATOM   397  C C   . ASN   A 1 53  ? -11.789 15.999  28.675 1.000 27.151 0 53  ASN   A C   1 ? 
ATOM   398  O O   . ASN   A 1 53  ? -12.528 15.942  29.642 1.000 23.793 0 53  ASN   A O   1 ? 
ATOM   399  C CB  . ASN   A 1 53  ? -13.308 17.653  27.474 1.000 34.371 0 53  ASN   A CB  1 ? 
ATOM   400  C CG  . ASN   A 1 53  ? -12.656 18.887  28.074 1.000 36.315 0 53  ASN   A CG  1 ? 
ATOM   401  O OD1 . ASN   A 1 53  ? -11.785 18.803  28.945 1.000 34.031 0 53  ASN   A OD1 1 ? 
ATOM   402  N ND2 . ASN   A 1 53  ? -13.085 20.054  27.626 1.000 40.295 0 53  ASN   A ND2 1 ? 
ATOM   403  N N   . TYR   A 1 54  ? -10.506 15.630  28.710 1.000 26.402 0 54  TYR   A N   1 ? 
ATOM   404  C CA  . TYR   A 1 54  ? -9.924  14.929  29.843 1.000 24.053 0 54  TYR   A CA  1 ? 
ATOM   405  C C   . TYR   A 1 54  ? -9.830  15.839  31.062 1.000 21.536 0 54  TYR   A C   1 ? 
ATOM   406  O O   . TYR   A 1 54  ? -10.068 15.390  32.169 1.000 20.839 0 54  TYR   A O   1 ? 
ATOM   407  C CB  . TYR   A 1 54  ? -8.520  14.415  29.500 1.000 22.348 0 54  TYR   A CB  1 ? 
ATOM   408  C CG  . TYR   A 1 54  ? -8.523  13.162  28.635 1.000 22.328 0 54  TYR   A CG  1 ? 
ATOM   409  C CD1 . TYR   A 1 54  ? -8.936  11.954  29.146 1.000 22.902 0 54  TYR   A CD1 1 ? 
ATOM   410  C CD2 . TYR   A 1 54  ? -8.151  13.196  27.297 1.000 22.558 0 54  TYR   A CD2 1 ? 
ATOM   411  C CE1 . TYR   A 1 54  ? -8.973  10.816  28.363 1.000 22.155 0 54  TYR   A CE1 1 ? 
ATOM   412  C CE2 . TYR   A 1 54  ? -8.164  12.058  26.505 1.000 21.433 0 54  TYR   A CE2 1 ? 
ATOM   413  C CZ  . TYR   A 1 54  ? -8.555  10.858  27.049 1.000 20.431 0 54  TYR   A CZ  1 ? 
ATOM   414  O OH  . TYR   A 1 54  ? -8.594  9.715   26.316 1.000 19.341 0 54  TYR   A OH  1 ? 
ATOM   415  N N   . GLU   A 1 55  ? -9.414  17.088  30.871 1.000 22.613 0 55  GLU   A N   1 ? 
ATOM   416  C CA  . GLU   A 1 55  ? -9.366  18.053  31.967 1.000 25.582 0 55  GLU   A CA  1 ? 
ATOM   417  C C   . GLU   A 1 55  ? -10.753 18.114  32.606 1.000 24.198 0 55  GLU   A C   1 ? 
ATOM   418  O O   . GLU   A 1 55  ? -10.913 17.936  33.820 1.000 21.311 0 55  GLU   A O   1 ? 
ATOM   419  C CB  . GLU   A 1 55  ? -8.899  19.422  31.462 1.000 30.945 0 55  GLU   A CB  1 ? 
ATOM   420  C CG  . GLU   A 1 55  ? -7.470  19.458  30.908 1.000 38.288 0 55  GLU   A CG  1 ? 
ATOM   421  C CD  . GLU   A 1 55  ? -7.225  18.944  29.488 1.000 45.957 0 55  GLU   A CD  1 ? 
ATOM   422  O OE1 . GLU   A 1 55  ? -8.212  18.570  28.769 1.000 43.022 0 55  GLU   A OE1 1 ? 
ATOM   423  O OE2 . GLU   A 1 55  ? -6.028  18.908  29.088 1.000 53.565 0 55  GLU   A OE2 1 ? 
ATOM   424  N N   . ASP   A 1 56  ? -11.788 18.238  31.758 1.000 24.317 0 56  ASP   A N   1 ? 
ATOM   425  C CA  . ASP   A 1 56  ? -13.142 18.315  32.269 1.000 24.628 0 56  ASP   A CA  1 ? 
ATOM   426  C C   . ASP   A 1 56  ? -13.512 17.045  33.023 1.000 24.052 0 56  ASP   A C   1 ? 
ATOM   427  O O   . ASP   A 1 56  ? -14.098 17.120  34.094 1.000 25.802 0 56  ASP   A O   1 ? 
ATOM   428  C CB  . ASP   A 1 56  ? -14.190 18.587  31.188 1.000 29.640 0 56  ASP   A CB  1 ? 
ATOM   429  C CG  . ASP   A 1 56  ? -15.545 18.896  31.801 1.000 31.837 0 56  ASP   A CG  1 ? 
ATOM   430  O OD1 . ASP   A 1 56  ? -15.689 19.992  32.388 1.000 35.964 0 56  ASP   A OD1 1 ? 
ATOM   431  O OD2 . ASP   A 1 56  ? -16.389 17.998  31.801 1.000 34.515 0 56  ASP   A OD2 1 ? 
ATOM   432  N N   . LEU   A 1 57  ? -13.225 15.874  32.464 1.000 23.390 0 57  LEU   A N   1 ? 
ATOM   433  C CA  . LEU   A 1 57  ? -13.636 14.632  33.106 1.000 23.298 0 57  LEU   A CA  1 ? 
ATOM   434  C C   . LEU   A 1 57  ? -12.907 14.462  34.438 1.000 22.217 0 57  LEU   A C   1 ? 
ATOM   435  O O   . LEU   A 1 57  ? -13.465 13.931  35.381 1.000 22.637 0 57  LEU   A O   1 ? 
ATOM   436  C CB  . LEU   A 1 57  ? -13.373 13.447  32.162 1.000 25.407 0 57  LEU   A CB  1 ? 
ATOM   437  C CG  . LEU   A 1 57  ? -14.252 13.405  30.904 1.000 27.542 0 57  LEU   A CG  1 ? 
ATOM   438  C CD1 . LEU   A 1 57  ? -13.745 12.372  29.893 1.000 27.111 0 57  LEU   A CD1 1 ? 
ATOM   439  C CD2 . LEU   A 1 57  ? -15.714 13.143  31.251 1.000 26.578 0 57  LEU   A CD2 1 ? 
ATOM   440  N N   . LEU   A 1 58  ? -11.648 14.890  34.532 1.000 22.852 0 58  LEU   A N   1 ? 
ATOM   441  C CA  . LEU   A 1 58  ? -10.908 14.717  35.775 1.000 22.343 0 58  LEU   A CA  1 ? 
ATOM   442  C C   . LEU   A 1 58  ? -11.451 15.609  36.900 1.000 21.758 0 58  LEU   A C   1 ? 
ATOM   443  O O   . LEU   A 1 58  ? -11.595 15.149  38.016 1.000 22.573 0 58  LEU   A O   1 ? 
ATOM   444  C CB  . LEU   A 1 58  ? -9.416  14.955  35.532 1.000 21.591 0 58  LEU   A CB  1 ? 
ATOM   445  C CG  . LEU   A 1 58  ? -8.545  14.622  36.739 1.000 22.796 0 58  LEU   A CG  1 ? 
ATOM   446  C CD1 . LEU   A 1 58  ? -8.526  13.129  36.964 1.000 24.986 0 58  LEU   A CD1 1 ? 
ATOM   447  C CD2 . LEU   A 1 58  ? -7.151  15.132  36.554 1.000 23.024 0 58  LEU   A CD2 1 ? 
ATOM   448  N N   . ILE   A 1 59  ? -11.818 16.858  36.612 1.000 26.187 0 59  ILE   A N   1 ? 
ATOM   449  C CA  . ILE   A 1 59  ? -12.474 17.731  37.586 1.000 24.783 0 59  ILE   A CA  1 ? 
ATOM   450  C C   . ILE   A 1 59  ? -13.638 17.010  38.244 1.000 27.741 0 59  ILE   A C   1 ? 
ATOM   451  O O   . ILE   A 1 59  ? -13.848 17.147  39.442 1.000 28.075 0 59  ILE   A O   1 ? 
ATOM   452  C CB  . ILE   A 1 59  ? -12.979 19.020  36.910 1.000 25.492 0 59  ILE   A CB  1 ? 
ATOM   453  C CG1 . ILE   A 1 59  ? -11.805 19.948  36.590 1.000 24.945 0 59  ILE   A CG1 1 ? 
ATOM   454  C CG2 . ILE   A 1 59  ? -14.053 19.731  37.743 1.000 25.617 0 59  ILE   A CG2 1 ? 
ATOM   455  C CD1 . ILE   A 1 59  ? -12.198 21.092  35.693 1.000 26.956 0 59  ILE   A CD1 1 ? 
ATOM   456  N N   . ARG   A 1 60  ? -14.397 16.264  37.440 1.000 30.760 0 60  ARG   A N   1 ? 
ATOM   457  C CA  . ARG   A 1 60  ? -15.624 15.642  37.901 1.000 35.153 0 60  ARG   A CA  1 ? 
ATOM   458  C C   . ARG   A 1 60  ? -15.326 14.418  38.760 1.000 32.581 0 60  ARG   A C   1 ? 
ATOM   459  O O   . ARG   A 1 60  ? -16.218 13.938  39.443 1.000 34.177 0 60  ARG   A O   1 ? 
ATOM   460  C CB  . ARG   A 1 60  ? -16.534 15.380  36.693 1.000 43.114 0 60  ARG   A CB  1 ? 
ATOM   461  C CG  . ARG   A 1 60  ? -17.245 16.644  36.214 1.000 48.712 0 60  ARG   A CG  1 ? 
ATOM   462  C CD  . ARG   A 1 60  ? -17.610 16.721  34.742 1.000 56.868 0 60  ARG   A CD  1 ? 
ATOM   463  N NE  . ARG   A 1 60  ? -18.433 15.618  34.261 1.000 65.706 0 60  ARG   A NE  1 ? 
ATOM   464  C CZ  . ARG   A 1 60  ? -18.858 15.475  33.003 1.000 71.523 0 60  ARG   A CZ  1 ? 
ATOM   465  N NH1 . ARG   A 1 60  ? -19.496 14.376  32.639 1.000 73.195 0 60  ARG   A NH1 1 ? 
ATOM   466  N NH2 . ARG   A 1 60  ? -18.627 16.413  32.099 1.000 68.305 0 60  ARG   A NH2 1 ? 
ATOM   467  N N   . LYS   A 1 61  ? -14.070 13.959  38.794 1.000 29.763 0 61  LYS   A N   1 ? 
ATOM   468  C CA  . LYS   A 1 61  ? -13.678 12.839  39.639 1.000 28.172 0 61  LYS   A CA  1 ? 
ATOM   469  C C   . LYS   A 1 61  ? -13.160 13.306  40.999 1.000 26.567 0 61  LYS   A C   1 ? 
ATOM   470  O O   . LYS   A 1 61  ? -12.669 14.426  41.131 1.000 27.250 0 61  LYS   A O   1 ? 
ATOM   471  C CB  . LYS   A 1 61  ? -12.551 12.036  38.969 1.000 30.166 0 61  LYS   A CB  1 ? 
ATOM   472  C CG  . LYS   A 1 61  ? -12.890 11.438  37.611 1.000 30.564 0 61  LYS   A CG  1 ? 
ATOM   473  C CD  . LYS   A 1 61  ? -13.962 10.386  37.631 1.000 32.705 0 61  LYS   A CD  1 ? 
ATOM   474  C CE  . LYS   A 1 61  ? -14.570 10.187  36.260 1.000 35.656 0 61  LYS   A CE  1 ? 
ATOM   475  N NZ  . LYS   A 1 61  ? -15.509 9.043   36.257 1.000 36.837 0 61  LYS   A NZ  1 ? 
ATOM   476  N N   . SER   A 1 62  ? -13.219 12.394  41.978 1.000 25.804 0 62  SER   A N   1 ? 
ATOM   477  C CA  . SER   A 1 62  ? -12.671 12.592  43.313 1.000 29.211 0 62  SER   A CA  1 ? 
ATOM   478  C C   . SER   A 1 62  ? -11.696 11.455  43.634 1.000 25.447 0 62  SER   A C   1 ? 
ATOM   479  O O   . SER   A 1 62  ? -11.738 10.406  42.998 1.000 23.604 0 62  SER   A O   1 ? 
ATOM   480  C CB  . SER   A 1 62  ? -13.768 12.610  44.355 1.000 32.728 0 62  SER   A CB  1 ? 
ATOM   481  O OG  . SER   A 1 62  ? -14.126 11.273  44.710 1.000 34.883 0 62  SER   A OG  1 ? 
ATOM   482  N N   . ASN   A 1 63  ? -10.875 11.639  44.671 1.000 23.877 0 63  ASN   A N   1 ? 
ATOM   483  C CA  . ASN   A 1 63  ? -9.922  10.622  45.080 1.000 24.142 0 63  ASN   A CA  1 ? 
ATOM   484  C C   . ASN   A 1 63  ? -10.601 9.264   45.235 1.000 26.051 0 63  ASN   A C   1 ? 
ATOM   485  O O   . ASN   A 1 63  ? -10.000 8.239   44.881 1.000 20.669 0 63  ASN   A O   1 ? 
ATOM   486  C CB  . ASN   A 1 63  ? -9.179  10.989  46.359 1.000 24.639 0 63  ASN   A CB  1 ? 
ATOM   487  C CG  . ASN   A 1 63  ? -8.193  12.115  46.152 1.000 23.598 0 63  ASN   A CG  1 ? 
ATOM   488  O OD1 . ASN   A 1 63  ? -7.585  12.260  45.096 1.000 22.187 0 63  ASN   A OD1 1 ? 
ATOM   489  N ND2 . ASN   A 1 63  ? -8.029  12.937  47.163 1.000 26.985 0 63  ASN   A ND2 1 ? 
ATOM   490  N N   . HIS   A 1 64  ? -11.850 9.261   45.731 1.000 25.480 0 64  HIS   A N   1 ? 
ATOM   491  C CA  . HIS   A 1 64  ? -12.539 8.006   46.012 1.000 27.115 0 64  HIS   A CA  1 ? 
ATOM   492  C C   . HIS   A 1 64  ? -13.092 7.345   44.738 1.000 23.293 0 64  HIS   A C   1 ? 
ATOM   493  O O   . HIS   A 1 64  ? -13.500 6.189   44.755 1.000 21.011 0 64  HIS   A O   1 ? 
ATOM   494  C CB  . HIS   A 1 64  ? -13.605 8.187   47.108 1.000 32.816 0 64  HIS   A CB  1 ? 
ATOM   495  C CG  . HIS   A 1 64  ? -13.990 6.887   47.770 1.000 37.083 0 64  HIS   A CG  1 ? 
ATOM   496  N ND1 . HIS   A 1 64  ? -15.052 6.109   47.343 1.000 39.537 0 64  HIS   A ND1 1 ? 
ATOM   497  C CD2 . HIS   A 1 64  ? -13.402 6.195   48.782 1.000 39.366 0 64  HIS   A CD2 1 ? 
ATOM   498  C CE1 . HIS   A 1 64  ? -15.122 5.008   48.096 1.000 39.978 0 64  HIS   A CE1 1 ? 
ATOM   499  N NE2 . HIS   A 1 64  ? -14.126 5.036   48.975 1.000 39.055 0 64  HIS   A NE2 1 ? 
ATOM   500  N N   . ASN   A 1 65  ? -13.083 8.027   43.599 1.000 22.357 0 65  ASN   A N   1 ? 
ATOM   501  C CA  . ASN   A 1 65  ? -13.489 7.371   42.365 1.000 23.176 0 65  ASN   A CA  1 ? 
ATOM   502  C C   . ASN   A 1 65  ? -12.404 6.432   41.821 1.000 25.123 0 65  ASN   A C   1 ? 
ATOM   503  O O   . ASN   A 1 65  ? -12.650 5.730   40.851 1.000 25.306 0 65  ASN   A O   1 ? 
ATOM   504  C CB  . ASN   A 1 65  ? -13.807 8.365   41.255 1.000 24.388 0 65  ASN   A CB  1 ? 
ATOM   505  C CG  . ASN   A 1 65  ? -14.975 9.266   41.585 1.000 27.392 0 65  ASN   A CG  1 ? 
ATOM   506  O OD1 . ASN   A 1 65  ? -14.906 10.463  41.345 1.000 29.112 0 65  ASN   A OD1 1 ? 
ATOM   507  N ND2 . ASN   A 1 65  ? -16.031 8.707   42.146 1.000 26.920 0 65  ASN   A ND2 1 ? 
ATOM   508  N N   . PHE   A 1 66  ? -11.198 6.441   42.400 1.000 25.101 0 66  PHE   A N   1 ? 
ATOM   509  C CA  . PHE   A 1 66  ? -10.108 5.625   41.887 1.000 24.547 0 66  PHE   A CA  1 ? 
ATOM   510  C C   . PHE   A 1 66  ? -9.862  4.446   42.832 1.000 25.982 0 66  PHE   A C   1 ? 
ATOM   511  O O   . PHE   A 1 66  ? -9.430  4.630   43.961 1.000 24.492 0 66  PHE   A O   1 ? 
ATOM   512  C CB  . PHE   A 1 66  ? -8.851  6.485   41.715 1.000 22.254 0 66  PHE   A CB  1 ? 
ATOM   513  C CG  . PHE   A 1 66  ? -8.991  7.596   40.707 1.000 21.290 0 66  PHE   A CG  1 ? 
ATOM   514  C CD1 . PHE   A 1 66  ? -8.906  7.346   39.350 1.000 21.744 0 66  PHE   A CD1 1 ? 
ATOM   515  C CD2 . PHE   A 1 66  ? -9.238  8.895   41.110 1.000 21.898 0 66  PHE   A CD2 1 ? 
ATOM   516  C CE1 . PHE   A 1 66  ? -9.045  8.375   38.429 1.000 21.457 0 66  PHE   A CE1 1 ? 
ATOM   517  C CE2 . PHE   A 1 66  ? -9.385  9.924   40.189 1.000 20.252 0 66  PHE   A CE2 1 ? 
ATOM   518  C CZ  . PHE   A 1 66  ? -9.312  9.656   38.850 1.000 21.690 0 66  PHE   A CZ  1 ? 
ATOM   519  N N   . LEU   A 1 67  ? -10.106 3.228   42.341 1.000 27.263 0 67  LEU   A N   1 ? 
ATOM   520  C CA  . LEU   A 1 67  ? -9.849  2.012   43.097 1.000 26.434 0 67  LEU   A CA  1 ? 
ATOM   521  C C   . LEU   A 1 67  ? -8.540  1.382   42.612 1.000 25.300 0 67  LEU   A C   1 ? 
ATOM   522  O O   . LEU   A 1 67  ? -8.452  0.873   41.490 1.000 25.860 0 67  LEU   A O   1 ? 
ATOM   523  C CB  . LEU   A 1 67  ? -11.047 1.075   42.908 1.000 26.762 0 67  LEU   A CB  1 ? 
ATOM   524  C CG  . LEU   A 1 67  ? -10.882 -0.343  43.454 1.000 29.504 0 67  LEU   A CG  1 ? 
ATOM   525  C CD1 . LEU   A 1 67  ? -10.473 -0.325  44.916 1.000 30.143 0 67  LEU   A CD1 1 ? 
ATOM   526  C CD2 . LEU   A 1 67  ? -12.179 -1.134  43.276 1.000 30.439 0 67  LEU   A CD2 1 ? 
ATOM   527  N N   . VAL   A 1 68  ? -7.539  1.410   43.493 1.000 22.901 0 68  VAL   A N   1 ? 
ATOM   528  C CA  . VAL   A 1 68  ? -6.212  0.885   43.237 1.000 22.596 0 68  VAL   A CA  1 ? 
ATOM   529  C C   . VAL   A 1 68  ? -5.996  -0.365  44.072 1.000 21.273 0 68  VAL   A C   1 ? 
ATOM   530  O O   . VAL   A 1 68  ? -6.112  -0.304  45.289 1.000 20.676 0 68  VAL   A O   1 ? 
ATOM   531  C CB  . VAL   A 1 68  ? -5.131  1.923   43.564 1.000 21.299 0 68  VAL   A CB  1 ? 
ATOM   532  C CG1 . VAL   A 1 68  ? -3.733  1.405   43.231 1.000 22.213 0 68  VAL   A CG1 1 ? 
ATOM   533  C CG2 . VAL   A 1 68  ? -5.408  3.224   42.850 1.000 21.892 0 68  VAL   A CG2 1 ? 
ATOM   534  N N   . GLN   A 1 69  ? -5.609  -1.454  43.405 1.000 22.059 0 69  GLN   A N   1 ? 
ATOM   535  C CA  . GLN   A 1 69  ? -5.457  -2.752  44.048 1.000 25.180 0 69  GLN   A CA  1 ? 
ATOM   536  C C   . GLN   A 1 69  ? -4.069  -3.299  43.729 1.000 23.170 0 69  GLN   A C   1 ? 
ATOM   537  O O   . GLN   A 1 69  ? -3.706  -3.399  42.561 1.000 20.387 0 69  GLN   A O   1 ? 
ATOM   538  C CB  . GLN   A 1 69  ? -6.541  -3.731  43.584 1.000 27.576 0 69  GLN   A CB  1 ? 
ATOM   539  C CG  . GLN   A 1 69  ? -7.917  -3.487  44.194 1.000 35.537 0 69  GLN   A CG  1 ? 
ATOM   540  C CD  . GLN   A 1 69  ? -9.055  -4.094  43.398 1.000 42.935 0 69  GLN   A CD  1 ? 
ATOM   541  O OE1 . GLN   A 1 69  ? -9.892  -4.821  43.921 1.000 44.620 0 69  GLN   A OE1 1 ? 
ATOM   542  N NE2 . GLN   A 1 69  ? -9.131  -3.762  42.117 1.000 46.530 0 69  GLN   A NE2 1 ? 
ATOM   543  N N   . ALA   A 1 70  ? -3.302  -3.601  44.783 1.000 24.310 0 70  ALA   A N   1 ? 
ATOM   544  C CA  . ALA   A 1 70  ? -2.055  -4.352  44.711 1.000 25.293 0 70  ALA   A CA  1 ? 
ATOM   545  C C   . ALA   A 1 70  ? -2.248  -5.706  45.390 1.000 28.078 0 70  ALA   A C   1 ? 
ATOM   546  O O   . ALA   A 1 70  ? -2.288  -5.781  46.615 1.000 29.746 0 70  ALA   A O   1 ? 
ATOM   547  C CB  . ALA   A 1 70  ? -0.950  -3.576  45.393 1.000 24.305 0 70  ALA   A CB  1 ? 
ATOM   548  N N   . GLY   A 1 71  ? -2.360  -6.784  44.606 1.000 31.737 0 71  GLY   A N   1 ? 
ATOM   549  C CA  . GLY   A 1 71  ? -2.834  -8.041  45.165 1.000 33.298 0 71  GLY   A CA  1 ? 
ATOM   550  C C   . GLY   A 1 71  ? -4.232  -7.853  45.756 1.000 35.746 0 71  GLY   A C   1 ? 
ATOM   551  O O   . GLY   A 1 71  ? -5.116  -7.355  45.068 1.000 36.719 0 71  GLY   A O   1 ? 
ATOM   552  N N   . ASN   A 1 72  ? -4.417  -8.189  47.038 1.000 43.445 0 72  ASN   A N   1 ? 
ATOM   553  C CA  . ASN   A 1 72  ? -5.731  -8.084  47.667 1.000 50.021 0 72  ASN   A CA  1 ? 
ATOM   554  C C   . ASN   A 1 72  ? -5.879  -6.741  48.376 1.000 50.107 0 72  ASN   A C   1 ? 
ATOM   555  O O   . ASN   A 1 72  ? -6.983  -6.381  48.781 1.000 55.005 0 72  ASN   A O   1 ? 
ATOM   556  C CB  . ASN   A 1 72  ? -6.004  -9.168  48.708 1.000 55.362 0 72  ASN   A CB  1 ? 
ATOM   557  C CG  . ASN   A 1 72  ? -5.269  -10.458 48.426 1.000 61.242 0 72  ASN   A CG  1 ? 
ATOM   558  O OD1 . ASN   A 1 72  ? -5.835  -11.388 47.856 1.000 60.464 0 72  ASN   A OD1 1 ? 
ATOM   559  N ND2 . ASN   A 1 72  ? -4.000  -10.508 48.799 1.000 63.626 0 72  ASN   A ND2 1 ? 
ATOM   560  N N   . VAL   A 1 73  ? -4.766  -6.008  48.516 1.000 40.834 0 73  VAL   A N   1 ? 
ATOM   561  C CA  . VAL   A 1 73  ? -4.758  -4.763  49.262 1.000 37.766 0 73  VAL   A CA  1 ? 
ATOM   562  C C   . VAL   A 1 73  ? -5.255  -3.610  48.381 1.000 34.497 0 73  VAL   A C   1 ? 
ATOM   563  O O   . VAL   A 1 73  ? -4.709  -3.348  47.304 1.000 27.214 0 73  VAL   A O   1 ? 
ATOM   564  C CB  . VAL   A 1 73  ? -3.346  -4.491  49.812 1.000 39.125 0 73  VAL   A CB  1 ? 
ATOM   565  C CG1 . VAL   A 1 73  ? -3.272  -3.167  50.554 1.000 40.114 0 73  VAL   A CG1 1 ? 
ATOM   566  C CG2 . VAL   A 1 73  ? -2.871  -5.635  50.692 1.000 42.305 0 73  VAL   A CG2 1 ? 
ATOM   567  N N   . GLN   A 1 74  ? -6.291  -2.906  48.852 1.000 32.523 0 74  GLN   A N   1 ? 
ATOM   568  C CA  . GLN   A 1 74  ? -6.665  -1.636  48.256 1.000 32.720 0 74  GLN   A CA  1 ? 
ATOM   569  C C   . GLN   A 1 74  ? -5.696  -0.592  48.791 1.000 30.632 0 74  GLN   A C   1 ? 
ATOM   570  O O   . GLN   A 1 74  ? -5.360  -0.637  49.980 1.000 31.259 0 74  GLN   A O   1 ? 
ATOM   571  C CB  . GLN   A 1 74  ? -8.095  -1.227  48.591 1.000 39.472 0 74  GLN   A CB  1 ? 
ATOM   572  C CG  . GLN   A 1 74  ? -9.053  -2.406  48.674 1.000 50.899 0 74  GLN   A CG  1 ? 
ATOM   573  C CD  . GLN   A 1 74  ? -10.410 -2.104  48.081 1.000 61.143 0 74  GLN   A CD  1 ? 
ATOM   574  O OE1 . GLN   A 1 74  ? -11.006 -2.941  47.400 1.000 64.560 0 74  GLN   A OE1 1 ? 
ATOM   575  N NE2 . GLN   A 1 74  ? -10.908 -0.904  48.341 1.000 61.316 0 74  GLN   A NE2 1 ? 
ATOM   576  N N   . LEU   A 1 75  ? -5.211  0.281   47.898 1.000 25.792 0 75  LEU   A N   1 ? 
ATOM   577  C CA  . LEU   A 1 75  ? -4.367  1.404   48.280 1.000 25.506 0 75  LEU   A CA  1 ? 
ATOM   578  C C   . LEU   A 1 75  ? -5.232  2.658   48.263 1.000 27.506 0 75  LEU   A C   1 ? 
ATOM   579  O O   . LEU   A 1 75  ? -5.872  2.951   47.254 1.000 29.345 0 75  LEU   A O   1 ? 
ATOM   580  C CB  . LEU   A 1 75  ? -3.212  1.578   47.286 1.000 24.575 0 75  LEU   A CB  1 ? 
ATOM   581  C CG  . LEU   A 1 75  ? -2.337  0.351   47.031 1.000 25.767 0 75  LEU   A CG  1 ? 
ATOM   582  C CD1 . LEU   A 1 75  ? -1.251  0.673   46.025 1.000 26.613 0 75  LEU   A CD1 1 ? 
ATOM   583  C CD2 . LEU   A 1 75  ? -1.711  -0.147  48.329 1.000 27.174 0 75  LEU   A CD2 1 ? 
ATOM   584  N N   . ARG   A 1 76  ? -5.189  3.430   49.349 1.000 25.788 0 76  ARG   A N   1 ? 
ATOM   585  C CA  . ARG   A 1 76  ? -5.998  4.628   49.425 1.000 27.096 0 76  ARG   A CA  1 ? 
ATOM   586  C C   . ARG   A 1 76  ? -5.348  5.735   48.590 1.000 24.251 0 76  ARG   A C   1 ? 
ATOM   587  O O   . ARG   A 1 76  ? -4.180  6.068   48.772 1.000 24.549 0 76  ARG   A O   1 ? 
ATOM   588  C CB  . ARG   A 1 76  ? -6.213  5.009   50.895 1.000 31.861 0 76  ARG   A CB  1 ? 
ATOM   589  C CG  . ARG   A 1 76  ? -6.998  6.304   51.094 1.000 34.749 0 76  ARG   A CG  1 ? 
ATOM   590  C CD  . ARG   A 1 76  ? -6.974  6.744   52.551 1.000 35.945 0 76  ARG   A CD  1 ? 
ATOM   591  N NE  . ARG   A 1 76  ? -7.897  5.928   53.315 1.000 39.364 0 76  ARG   A NE  1 ? 
ATOM   592  C CZ  . ARG   A 1 76  ? -9.229  6.005   53.245 1.000 41.434 0 76  ARG   A CZ  1 ? 
ATOM   593  N NH1 . ARG   A 1 76  ? -9.822  7.003   52.620 1.000 40.923 0 76  ARG   A NH1 1 ? 
ATOM   594  N NH2 . ARG   A 1 76  ? -9.975  5.106   53.859 1.000 43.931 0 76  ARG   A NH2 1 ? 
ATOM   595  N N   . VAL   A 1 77  ? -6.135  6.309   47.682 1.000 20.808 0 77  VAL   A N   1 ? 
ATOM   596  C CA  . VAL   A 1 77  ? -5.722  7.431   46.868 1.000 20.954 0 77  VAL   A CA  1 ? 
ATOM   597  C C   . VAL   A 1 77  ? -5.975  8.709   47.650 1.000 23.176 0 77  VAL   A C   1 ? 
ATOM   598  O O   . VAL   A 1 77  ? -7.109  8.923   48.086 1.000 22.292 0 77  VAL   A O   1 ? 
ATOM   599  C CB  . VAL   A 1 77  ? -6.512  7.453   45.549 1.000 21.562 0 77  VAL   A CB  1 ? 
ATOM   600  C CG1 . VAL   A 1 77  ? -6.173  8.675   44.724 1.000 21.362 0 77  VAL   A CG1 1 ? 
ATOM   601  C CG2 . VAL   A 1 77  ? -6.321  6.165   44.751 1.000 22.666 0 77  VAL   A CG2 1 ? 
ATOM   602  N N   . ILE   A 1 78  ? -4.933  9.551   47.783 1.000 23.341 0 78  ILE   A N   1 ? 
ATOM   603  C CA  . ILE   A 1 78  ? -5.018  10.779  48.572 1.000 23.202 0 78  ILE   A CA  1 ? 
ATOM   604  C C   . ILE   A 1 78  ? -4.780  12.011  47.698 1.000 22.484 0 78  ILE   A C   1 ? 
ATOM   605  O O   . ILE   A 1 78  ? -4.692  13.127  48.194 1.000 23.511 0 78  ILE   A O   1 ? 
ATOM   606  C CB  . ILE   A 1 78  ? -4.030  10.736  49.751 1.000 24.973 0 78  ILE   A CB  1 ? 
ATOM   607  C CG1 . ILE   A 1 78  ? -2.586  10.496  49.294 1.000 27.114 0 78  ILE   A CG1 1 ? 
ATOM   608  C CG2 . ILE   A 1 78  ? -4.482  9.695   50.769 1.000 25.271 0 78  ILE   A CG2 1 ? 
ATOM   609  C CD1 . ILE   A 1 78  ? -1.536  10.882  50.333 1.000 27.169 0 78  ILE   A CD1 1 ? 
ATOM   610  N N   . GLY   A 1 79  ? -4.702  11.820  46.386 1.000 21.604 0 79  GLY   A N   1 ? 
ATOM   611  C CA  . GLY   A 1 79  ? -4.426  12.917  45.481 1.000 21.435 0 79  GLY   A CA  1 ? 
ATOM   612  C C   . GLY   A 1 79  ? -4.349  12.401  44.051 1.000 22.884 0 79  GLY   A C   1 ? 
ATOM   613  O O   . GLY   A 1 79  ? -4.110  11.200  43.833 1.000 21.184 0 79  GLY   A O   1 ? 
ATOM   614  N N   . HIS   A 1 80  ? -4.537  13.329  43.106 1.000 23.000 0 80  HIS   A N   1 ? 
ATOM   615  C CA  . HIS   A 1 80  ? -4.528  13.001  41.699 1.000 23.795 0 80  HIS   A CA  1 ? 
ATOM   616  C C   . HIS   A 1 80  ? -4.248  14.242  40.853 1.000 24.557 0 80  HIS   A C   1 ? 
ATOM   617  O O   . HIS   A 1 80  ? -4.760  15.329  41.115 1.000 21.896 0 80  HIS   A O   1 ? 
ATOM   618  C CB  . HIS   A 1 80  ? -5.849  12.352  41.301 1.000 24.115 0 80  HIS   A CB  1 ? 
ATOM   619  C CG  . HIS   A 1 80  ? -7.059  13.232  41.448 1.000 25.322 0 80  HIS   A CG  1 ? 
ATOM   620  N ND1 . HIS   A 1 80  ? -7.862  13.295  42.573 1.000 24.866 0 80  HIS   A ND1 1 ? 
ATOM   621  C CD2 . HIS   A 1 80  ? -7.658  13.993  40.517 1.000 22.366 0 80  HIS   A CD2 1 ? 
ATOM   622  C CE1 . HIS   A 1 80  ? -8.881  14.105  42.325 1.000 24.368 0 80  HIS   A CE1 1 ? 
ATOM   623  N NE2 . HIS   A 1 80  ? -8.781  14.520  41.076 1.000 24.096 0 80  HIS   A NE2 1 ? 
ATOM   624  N N   . SER   A 1 81  ? -3.408  14.035  39.836 1.000 22.486 0 81  SER   A N   1 ? 
ATOM   625  C CA  . SER   A 1 81  ? -3.141  15.009  38.804 1.000 24.845 0 81  SER   A CA  1 ? 
ATOM   626  C C   . SER   A 1 81  ? -2.918  14.297  37.466 1.000 23.317 0 81  SER   A C   1 ? 
ATOM   627  O O   . SER   A 1 81  ? -2.733  13.078  37.401 1.000 21.901 0 81  SER   A O   1 ? 
ATOM   628  C CB  . SER   A 1 81  ? -1.967  15.882  39.181 1.000 24.330 0 81  SER   A CB  1 ? 
ATOM   629  O OG  . SER   A 1 81  ? -0.788  15.114  39.299 1.000 25.588 0 81  SER   A OG  1 ? 
ATOM   630  N N   . MET   A 1 82  ? -2.874  15.110  36.415 1.000 21.469 0 82  MET   A N   1 ? 
ATOM   631  C CA  . MET   A 1 82  ? -2.655  14.660  35.057 1.000 22.355 0 82  MET   A CA  1 ? 
ATOM   632  C C   . MET   A 1 82  ? -1.397  15.341  34.518 1.000 20.322 0 82  MET   A C   1 ? 
ATOM   633  O O   . MET   A 1 82  ? -1.188  16.530  34.709 1.000 19.251 0 82  MET   A O   1 ? 
ATOM   634  C CB  . MET   A 1 82  ? -3.916  15.008  34.259 1.000 25.119 0 82  MET   A CB  1 ? 
ATOM   635  C CG  . MET   A 1 82  ? -3.862  14.764  32.780 1.000 27.672 0 82  MET   A CG  1 ? 
ATOM   636  S SD  . MET   A 1 82  ? -5.563  14.680  32.143 1.000 32.262 0 82  MET   A SD  1 ? 
ATOM   637  C CE  . MET   A 1 82  ? -6.068  16.390  32.252 1.000 34.570 0 82  MET   A CE  1 ? 
ATOM   638  N N   . GLN   A 1 83  ? -0.500  14.558  33.919 1.000 20.070 0 83  GLN   A N   1 ? 
ATOM   639  C CA  . GLN   A 1 83  ? 0.620   15.106  33.181 1.000 18.289 0 83  GLN   A CA  1 ? 
ATOM   640  C C   . GLN   A 1 83  ? 0.515   14.557  31.770 1.000 17.959 0 83  GLN   A C   1 ? 
ATOM   641  O O   . GLN   A 1 83  ? 0.658   13.348  31.570 1.000 15.795 0 83  GLN   A O   1 ? 
ATOM   642  C CB  . GLN   A 1 83  ? 1.925   14.734  33.877 1.000 20.381 0 83  GLN   A CB  1 ? 
ATOM   643  C CG  . GLN   A 1 83  ? 3.158   15.337  33.224 1.000 21.012 0 83  GLN   A CG  1 ? 
ATOM   644  C CD  . GLN   A 1 83  ? 4.439   14.882  33.886 1.000 22.265 0 83  GLN   A CD  1 ? 
ATOM   645  O OE1 . GLN   A 1 83  ? 4.456   13.966  34.698 1.000 22.524 0 83  GLN   A OE1 1 ? 
ATOM   646  N NE2 . GLN   A 1 83  ? 5.519   15.584  33.603 1.000 23.704 0 83  GLN   A NE2 1 ? 
ATOM   647  N N   . ASN   A 1 84  ? 0.219   15.444  30.807 1.000 17.591 0 84  ASN   A N   1 ? 
ATOM   648  C CA  . ASN   A 1 84  ? 0.058   15.036  29.420 1.000 17.875 0 84  ASN   A CA  1 ? 
ATOM   649  C C   . ASN   A 1 84  ? -0.966  13.909  29.414 1.000 16.757 0 84  ASN   A C   1 ? 
ATOM   650  O O   . ASN   A 1 84  ? -2.043  14.106  29.979 1.000 15.666 0 84  ASN   A O   1 ? 
ATOM   651  C CB  . ASN   A 1 84  ? 1.420   14.756  28.783 1.000 17.763 0 84  ASN   A CB  1 ? 
ATOM   652  C CG  . ASN   A 1 84  ? 2.276   16.002  28.892 1.000 19.688 0 84  ASN   A CG  1 ? 
ATOM   653  O OD1 . ASN   A 1 84  ? 1.825   17.081  28.523 1.000 22.266 0 84  ASN   A OD1 1 ? 
ATOM   654  N ND2 . ASN   A 1 84  ? 3.450   15.901  29.489 1.000 19.378 0 84  ASN   A ND2 1 ? 
ATOM   655  N N   . CYS   A 1 85  ? -0.639  12.731  28.850 1.000 15.776 0 85  CYS   A N   1 ? 
ATOM   656  C CA  . CYS   A 1 85  ? -1.649  11.687  28.730 1.000 16.406 0 85  CYS   A CA  1 ? 
ATOM   657  C C   . CYS   A 1 85  ? -1.553  10.642  29.844 1.000 16.325 0 85  CYS   A C   1 ? 
ATOM   658  O O   . CYS   A 1 85  ? -2.166  9.595   29.706 1.000 16.966 0 85  CYS   A O   1 ? 
ATOM   659  C CB  . CYS   A 1 85  ? -1.620  10.996  27.360 1.000 16.686 0 85  CYS   A CB  1 ? 
ATOM   660  S SG  . CYS   A 1 85  ? -1.689  12.133  25.944 1.000 18.875 0 85  CYS   A SG  1 ? 
ATOM   661  N N   . VAL   A 1 86  ? -0.803  10.882  30.929 1.000 17.973 0 86  VAL   A N   1 ? 
ATOM   662  C CA  . VAL   A 1 86  ? -0.835  9.970   32.065 1.000 19.683 0 86  VAL   A CA  1 ? 
ATOM   663  C C   . VAL   A 1 86  ? -1.499  10.652  33.264 1.000 20.428 0 86  VAL   A C   1 ? 
ATOM   664  O O   . VAL   A 1 86  ? -1.357  11.853  33.495 1.000 19.907 0 86  VAL   A O   1 ? 
ATOM   665  C CB  . VAL   A 1 86  ? 0.533   9.396   32.506 1.000 23.929 0 86  VAL   A CB  1 ? 
ATOM   666  C CG1 . VAL   A 1 86  ? 1.280   8.669   31.383 1.000 26.279 0 86  VAL   A CG1 1 ? 
ATOM   667  C CG2 . VAL   A 1 86  ? 1.415   10.451  33.142 1.000 25.928 0 86  VAL   A CG2 1 ? 
ATOM   668  N N   . LEU   A 1 87  ? -2.188  9.814   34.038 1.000 18.841 0 87  LEU   A N   1 ? 
ATOM   669  C CA  . LEU   A 1 87  ? -2.727  10.150  35.334 1.000 21.692 0 87  LEU   A CA  1 ? 
ATOM   670  C C   . LEU   A 1 87  ? -1.766  9.653   36.416 1.000 21.512 0 87  LEU   A C   1 ? 
ATOM   671  O O   . LEU   A 1 87  ? -1.222  8.546   36.319 1.000 21.993 0 87  LEU   A O   1 ? 
ATOM   672  C CB  . LEU   A 1 87  ? -4.097  9.473   35.413 1.000 24.350 0 87  LEU   A CB  1 ? 
ATOM   673  C CG  . LEU   A 1 87  ? -4.902  9.706   36.682 1.000 26.687 0 87  LEU   A CG  1 ? 
ATOM   674  C CD1 . LEU   A 1 87  ? -5.385  11.150  36.767 1.000 28.048 0 87  LEU   A CD1 1 ? 
ATOM   675  C CD2 . LEU   A 1 87  ? -6.072  8.742   36.723 1.000 27.684 0 87  LEU   A CD2 1 ? 
ATOM   676  N N   . LYS   A 1 88  ? -1.524  10.523  37.399 1.000 20.504 0 88  LYS   A N   1 ? 
ATOM   677  C CA  . LYS   A 1 88  ? -0.698  10.257  38.564 1.000 22.171 0 88  LYS   A CA  1 ? 
ATOM   678  C C   . LYS   A 1 88  ? -1.601  10.273  39.794 1.000 20.510 0 88  LYS   A C   1 ? 
ATOM   679  O O   . LYS   A 1 88  ? -2.222  11.284  40.095 1.000 21.769 0 88  LYS   A O   1 ? 
ATOM   680  C CB  . LYS   A 1 88  ? 0.406   11.309  38.683 1.000 24.256 0 88  LYS   A CB  1 ? 
ATOM   681  C CG  . LYS   A 1 88  ? 1.314   11.418  37.465 1.000 28.036 0 88  LYS   A CG  1 ? 
ATOM   682  C CD  . LYS   A 1 88  ? 2.577   12.198  37.727 1.000 30.399 0 88  LYS   A CD  1 ? 
ATOM   683  C CE  . LYS   A 1 88  ? 2.269   13.652  37.977 1.000 36.986 0 88  LYS   A CE  1 ? 
ATOM   684  N NZ  . LYS   A 1 88  ? 3.460   14.481  37.719 1.000 42.494 0 88  LYS   A NZ  1 ? 
ATOM   685  N N   . LEU   A 1 89  ? -1.721  9.117   40.444 1.000 20.945 0 89  LEU   A N   1 ? 
ATOM   686  C CA  . LEU   A 1 89  ? -2.510  8.945   41.654 1.000 20.293 0 89  LEU   A CA  1 ? 
ATOM   687  C C   . LEU   A 1 89  ? -1.553  8.845   42.831 1.000 20.873 0 89  LEU   A C   1 ? 
ATOM   688  O O   . LEU   A 1 89  ? -0.743  7.917   42.867 1.000 18.731 0 89  LEU   A O   1 ? 
ATOM   689  C CB  . LEU   A 1 89  ? -3.314  7.649   41.553 1.000 18.934 0 89  LEU   A CB  1 ? 
ATOM   690  C CG  . LEU   A 1 89  ? -4.256  7.587   40.371 1.000 19.432 0 89  LEU   A CG  1 ? 
ATOM   691  C CD1 . LEU   A 1 89  ? -5.040  6.299   40.404 1.000 19.821 0 89  LEU   A CD1 1 ? 
ATOM   692  C CD2 . LEU   A 1 89  ? -5.192  8.800   40.389 1.000 20.815 0 89  LEU   A CD2 1 ? 
ATOM   693  N N   . LYS   A 1 90  ? -1.628  9.822   43.742 1.000 21.380 0 90  LYS   A N   1 ? 
ATOM   694  C CA  . LYS   A 1 90  ? -0.884  9.740   44.983 1.000 23.006 0 90  LYS   A CA  1 ? 
ATOM   695  C C   . LYS   A 1 90  ? -1.644  8.817   45.930 1.000 21.244 0 90  LYS   A C   1 ? 
ATOM   696  O O   . LYS   A 1 90  ? -2.869  8.927   46.079 1.000 21.755 0 90  LYS   A O   1 ? 
ATOM   697  C CB  . LYS   A 1 90  ? -0.599  11.119  45.592 1.000 26.592 0 90  LYS   A CB  1 ? 
ATOM   698  C CG  . LYS   A 1 90  ? 0.297   11.005  46.819 1.000 31.373 0 90  LYS   A CG  1 ? 
ATOM   699  C CD  . LYS   A 1 90  ? 1.255   12.134  47.028 1.000 38.664 0 90  LYS   A CD  1 ? 
ATOM   700  C CE  . LYS   A 1 90  ? 0.766   13.167  48.016 1.000 42.178 0 90  LYS   A CE  1 ? 
ATOM   701  N NZ  . LYS   A 1 90  ? 1.924   13.858  48.635 1.000 44.229 0 90  LYS   A NZ  1 ? 
ATOM   702  N N   . VAL   A 1 91  ? -0.908  7.847   46.492 1.000 19.385 0 91  VAL   A N   1 ? 
ATOM   703  C CA  . VAL   A 1 91  ? -1.484  6.858   47.391 1.000 19.131 0 91  VAL   A CA  1 ? 
ATOM   704  C C   . VAL   A 1 91  ? -0.838  7.038   48.766 1.000 19.945 0 91  VAL   A C   1 ? 
ATOM   705  O O   . VAL   A 1 91  ? 0.210   7.662   48.848 1.000 20.598 0 91  VAL   A O   1 ? 
ATOM   706  C CB  . VAL   A 1 91  ? -1.318  5.429   46.822 1.000 18.696 0 91  VAL   A CB  1 ? 
ATOM   707  C CG1 . VAL   A 1 91  ? -2.245  5.218   45.642 1.000 19.001 0 91  VAL   A CG1 1 ? 
ATOM   708  C CG2 . VAL   A 1 91  ? 0.114   5.087   46.444 1.000 18.132 0 91  VAL   A CG2 1 ? 
ATOM   709  N N   . ASP   A 1 92  ? -1.433  6.465   49.833 1.000 23.323 0 92  ASP   A N   1 ? 
ATOM   710  C CA  . ASP   A 1 92  ? -0.986  6.705   51.203 1.000 23.409 0 92  ASP   A CA  1 ? 
ATOM   711  C C   . ASP   A 1 92  ? 0.166   5.764   51.583 1.000 23.214 0 92  ASP   A C   1 ? 
ATOM   712  O O   . ASP   A 1 92  ? 0.749   5.907   52.647 1.000 21.981 0 92  ASP   A O   1 ? 
ATOM   713  C CB  . ASP   A 1 92  ? -2.142  6.583   52.202 1.000 25.710 0 92  ASP   A CB  1 ? 
ATOM   714  C CG  . ASP   A 1 92  ? -2.744  5.193   52.369 1.000 26.086 0 92  ASP   A CG  1 ? 
ATOM   715  O OD1 . ASP   A 1 92  ? -2.309  4.261   51.672 1.000 29.569 0 92  ASP   A OD1 1 ? 
ATOM   716  O OD2 . ASP   A 1 92  ? -3.686  5.049   53.182 1.000 28.018 0 92  ASP   A OD2 1 ? 
ATOM   717  N N   . THR   A 1 93  ? 0.530   4.845   50.685 1.000 21.209 0 93  THR   A N   1 ? 
ATOM   718  C CA  . THR   A 1 93  ? 1.519   3.808   50.957 1.000 22.950 0 93  THR   A CA  1 ? 
ATOM   719  C C   . THR   A 1 93  ? 2.583   3.827   49.864 1.000 20.341 0 93  THR   A C   1 ? 
ATOM   720  O O   . THR   A 1 93  ? 2.239   3.773   48.692 1.000 20.260 0 93  THR   A O   1 ? 
ATOM   721  C CB  . THR   A 1 93  ? 0.826   2.436   50.972 1.000 24.657 0 93  THR   A CB  1 ? 
ATOM   722  O OG1 . THR   A 1 93  ? -0.252  2.537   51.893 1.000 27.447 0 93  THR   A OG1 1 ? 
ATOM   723  C CG2 . THR   A 1 93  ? 1.713   1.283   51.385 1.000 27.759 0 93  THR   A CG2 1 ? 
ATOM   724  N N   . ALA   A 1 94  ? 3.858   3.944   50.232 1.000 19.376 0 94  ALA   A N   1 ? 
ATOM   725  C CA  . ALA   A 1 94  ? 4.940   3.777   49.279 1.000 18.745 0 94  ALA   A CA  1 ? 
ATOM   726  C C   . ALA   A 1 94  ? 5.170   2.285   49.000 1.000 18.448 0 94  ALA   A C   1 ? 
ATOM   727  O O   . ALA   A 1 94  ? 5.154   1.455   49.902 1.000 20.100 0 94  ALA   A O   1 ? 
ATOM   728  C CB  . ALA   A 1 94  ? 6.170   4.446   49.804 1.000 18.411 0 94  ALA   A CB  1 ? 
ATOM   729  N N   . ASN   A 1 95  ? 5.350   1.960   47.720 1.000 18.477 0 95  ASN   A N   1 ? 
ATOM   730  C CA  . ASN   A 1 95  ? 5.637   0.609   47.275 1.000 17.161 0 95  ASN   A CA  1 ? 
ATOM   731  C C   . ASN   A 1 95  ? 6.964   0.105   47.853 1.000 15.380 0 95  ASN   A C   1 ? 
ATOM   732  O O   . ASN   A 1 95  ? 8.040   0.518   47.433 1.000 12.750 0 95  ASN   A O   1 ? 
ATOM   733  C CB  . ASN   A 1 95  ? 5.620   0.476   45.751 1.000 16.426 0 95  ASN   A CB  1 ? 
ATOM   734  C CG  . ASN   A 1 95  ? 5.721   -0.974  45.314 1.000 18.099 0 95  ASN   A CG  1 ? 
ATOM   735  O OD1 . ASN   A 1 95  ? 5.971   -1.874  46.115 1.000 16.375 0 95  ASN   A OD1 1 ? 
ATOM   736  N ND2 . ASN   A 1 95  ? 5.512   -1.218  44.038 1.000 18.916 0 95  ASN   A ND2 1 ? 
ATOM   737  N N   . PRO   A 1 96  ? 6.921   -0.910  48.740 1.000 17.732 0 96  PRO   A N   1 ? 
ATOM   738  C CA  . PRO   A 1 96  ? 8.133   -1.462  49.338 1.000 19.628 0 96  PRO   A CA  1 ? 
ATOM   739  C C   . PRO   A 1 96  ? 9.025   -2.160  48.309 1.000 21.611 0 96  PRO   A C   1 ? 
ATOM   740  O O   . PRO   A 1 96  ? 10.206  -2.367  48.543 1.000 20.926 0 96  PRO   A O   1 ? 
ATOM   741  C CB  . PRO   A 1 96  ? 7.656   -2.445  50.430 1.000 20.218 0 96  PRO   A CB  1 ? 
ATOM   742  C CG  . PRO   A 1 96  ? 6.145   -2.601  50.264 1.000 21.060 0 96  PRO   A CG  1 ? 
ATOM   743  C CD  . PRO   A 1 96  ? 5.696   -1.589  49.211 1.000 21.037 0 96  PRO   A CD  1 ? 
ATOM   744  N N   . LYS   A 1 97  ? 8.477   -2.493  47.140 1.000 23.042 0 97  LYS   A N   1 ? 
ATOM   745  C CA  . LYS   A 1 97  ? 9.274   -3.131  46.105 1.000 23.320 0 97  LYS   A CA  1 ? 
ATOM   746  C C   . LYS   A 1 97  ? 9.698   -2.143  45.019 1.000 22.686 0 97  LYS   A C   1 ? 
ATOM   747  O O   . LYS   A 1 97  ? 10.127  -2.572  43.957 1.000 20.607 0 97  LYS   A O   1 ? 
ATOM   748  C CB  . LYS   A 1 97  ? 8.471   -4.278  45.489 1.000 24.403 0 97  LYS   A CB  1 ? 
ATOM   749  C CG  . LYS   A 1 97  ? 7.958   -5.288  46.506 1.000 27.796 0 97  LYS   A CG  1 ? 
ATOM   750  C CD  . LYS   A 1 97  ? 7.096   -6.364  45.876 1.000 29.765 0 97  LYS   A CD  1 ? 
ATOM   751  C CE  . LYS   A 1 97  ? 6.606   -7.376  46.883 1.000 31.620 0 97  LYS   A CE  1 ? 
ATOM   752  N NZ  . LYS   A 1 97  ? 5.940   -8.496  46.183 1.000 33.678 0 97  LYS   A NZ  1 ? 
ATOM   753  N N   . THR   A 1 98  ? 9.616   -0.832  45.287 1.000 21.941 0 98  THR   A N   1 ? 
ATOM   754  C CA  . THR   A 1 98  ? 10.098  0.147   44.333 1.000 21.005 0 98  THR   A CA  1 ? 
ATOM   755  C C   . THR   A 1 98  ? 11.578  -0.087  44.065 1.000 21.769 0 98  THR   A C   1 ? 
ATOM   756  O O   . THR   A 1 98  ? 12.338  -0.021  45.006 1.000 20.725 0 98  THR   A O   1 ? 
ATOM   757  C CB  . THR   A 1 98  ? 9.922   1.578   44.854 1.000 20.085 0 98  THR   A CB  1 ? 
ATOM   758  O OG1 . THR   A 1 98  ? 8.530   1.752   45.109 1.000 18.742 0 98  THR   A OG1 1 ? 
ATOM   759  C CG2 . THR   A 1 98  ? 10.427  2.598   43.858 1.000 19.258 0 98  THR   A CG2 1 ? 
ATOM   760  N N   . PRO   A 1 99  ? 12.034  -0.388  42.820 1.000 22.925 0 99  PRO   A N   1 ? 
ATOM   761  C CA  . PRO   A 1 99  ? 13.467  -0.378  42.515 1.000 23.062 0 99  PRO   A CA  1 ? 
ATOM   762  C C   . PRO   A 1 99  ? 14.007  1.031   42.268 1.000 23.725 0 99  PRO   A C   1 ? 
ATOM   763  O O   . PRO   A 1 99  ? 13.243  2.015   42.245 1.000 24.052 0 99  PRO   A O   1 ? 
ATOM   764  C CB  . PRO   A 1 99  ? 13.521  -1.211  41.217 1.000 22.181 0 99  PRO   A CB  1 ? 
ATOM   765  C CG  . PRO   A 1 99  ? 12.235  -0.821  40.514 1.000 21.669 0 99  PRO   A CG  1 ? 
ATOM   766  C CD  . PRO   A 1 99  ? 11.219  -0.764  41.641 1.000 21.596 0 99  PRO   A CD  1 ? 
ATOM   767  N N   . LYS   A 1 100 ? 15.335  1.127   42.108 1.000 20.966 0 100 LYS   A N   1 ? 
ATOM   768  C CA  . LYS   A 1 100 ? 15.923  2.316   41.519 1.000 23.594 0 100 LYS   A CA  1 ? 
ATOM   769  C C   . LYS   A 1 100 ? 15.360  2.425   40.113 1.000 19.917 0 100 LYS   A C   1 ? 
ATOM   770  O O   . LYS   A 1 100 ? 15.280  1.418   39.401 1.000 17.106 0 100 LYS   A O   1 ? 
ATOM   771  C CB  . LYS   A 1 100 ? 17.447  2.226   41.427 1.000 29.569 0 100 LYS   A CB  1 ? 
ATOM   772  C CG  . LYS   A 1 100 ? 18.154  2.163   42.772 1.000 40.107 0 100 LYS   A CG  1 ? 
ATOM   773  C CD  . LYS   A 1 100 ? 19.619  1.730   42.705 1.000 48.328 0 100 LYS   A CD  1 ? 
ATOM   774  C CE  . LYS   A 1 100 ? 19.924  0.682   43.761 1.000 60.389 0 100 LYS   A CE  1 ? 
ATOM   775  N NZ  . LYS   A 1 100 ? 21.379  0.488   43.977 1.000 67.132 0 100 LYS   A NZ  1 ? 
ATOM   776  N N   . TYR   A 1 101 ? 14.936  3.624   39.735 1.000 17.650 0 101 TYR   A N   1 ? 
ATOM   777  C CA  . TYR   A 1 101 ? 14.289  3.758   38.448 1.000 19.019 0 101 TYR   A CA  1 ? 
ATOM   778  C C   . TYR   A 1 101 ? 14.585  5.142   37.912 1.000 19.063 0 101 TYR   A C   1 ? 
ATOM   779  O O   . TYR   A 1 101 ? 14.915  6.029   38.679 1.000 18.184 0 101 TYR   A O   1 ? 
ATOM   780  C CB  . TYR   A 1 101 ? 12.766  3.558   38.528 1.000 18.387 0 101 TYR   A CB  1 ? 
ATOM   781  C CG  . TYR   A 1 101 ? 11.990  4.580   39.357 1.000 18.524 0 101 TYR   A CG  1 ? 
ATOM   782  C CD1 . TYR   A 1 101 ? 11.891  4.460   40.734 1.000 18.508 0 101 TYR   A CD1 1 ? 
ATOM   783  C CD2 . TYR   A 1 101 ? 11.375  5.687   38.765 1.000 20.604 0 101 TYR   A CD2 1 ? 
ATOM   784  C CE1 . TYR   A 1 101 ? 11.204  5.388   41.498 1.000 20.078 0 101 TYR   A CE1 1 ? 
ATOM   785  C CE2 . TYR   A 1 101 ? 10.656  6.616   39.517 1.000 21.395 0 101 TYR   A CE2 1 ? 
ATOM   786  C CZ  . TYR   A 1 101 ? 10.552  6.454   40.887 1.000 23.474 0 101 TYR   A CZ  1 ? 
ATOM   787  O OH  . TYR   A 1 101 ? 9.861   7.361   41.651 1.000 24.165 0 101 TYR   A OH  1 ? 
ATOM   788  N N   . LYS   A 1 102 ? 14.356  5.309   36.614 1.000 18.757 0 102 LYS   A N   1 ? 
ATOM   789  C CA  . LYS   A 1 102 ? 14.163  6.622   36.040 1.000 20.540 0 102 LYS   A CA  1 ? 
ATOM   790  C C   . LYS   A 1 102 ? 13.238  6.491   34.841 1.000 19.183 0 102 LYS   A C   1 ? 
ATOM   791  O O   . LYS   A 1 102 ? 13.005  5.387   34.329 1.000 18.008 0 102 LYS   A O   1 ? 
ATOM   792  C CB  . LYS   A 1 102 ? 15.492  7.254   35.626 1.000 26.533 0 102 LYS   A CB  1 ? 
ATOM   793  C CG  . LYS   A 1 102 ? 16.438  6.341   34.865 1.000 30.949 0 102 LYS   A CG  1 ? 
ATOM   794  C CD  . LYS   A 1 102 ? 17.898  6.771   34.955 1.000 39.071 0 102 LYS   A CD  1 ? 
ATOM   795  C CE  . LYS   A 1 102 ? 18.377  7.509   33.725 1.000 43.161 0 102 LYS   A CE  1 ? 
ATOM   796  N NZ  . LYS   A 1 102 ? 18.584  6.555   32.612 1.000 50.963 0 102 LYS   A NZ  1 ? 
ATOM   797  N N   . PHE   A 1 103 ? 12.755  7.648   34.396 1.000 17.396 0 103 PHE   A N   1 ? 
ATOM   798  C CA  . PHE   A 1 103 ? 11.922  7.768   33.216 1.000 19.127 0 103 PHE   A CA  1 ? 
ATOM   799  C C   . PHE   A 1 103 ? 12.768  8.309   32.078 1.000 20.844 0 103 PHE   A C   1 ? 
ATOM   800  O O   . PHE   A 1 103 ? 13.347  9.376   32.203 1.000 20.131 0 103 PHE   A O   1 ? 
ATOM   801  C CB  . PHE   A 1 103 ? 10.759  8.725   33.499 1.000 18.414 0 103 PHE   A CB  1 ? 
ATOM   802  C CG  . PHE   A 1 103 ? 9.794   8.269   34.567 1.000 17.013 0 103 PHE   A CG  1 ? 
ATOM   803  C CD1 . PHE   A 1 103 ? 9.769   6.952   35.004 1.000 16.897 0 103 PHE   A CD1 1 ? 
ATOM   804  C CD2 . PHE   A 1 103 ? 8.861   9.155   35.098 1.000 16.790 0 103 PHE   A CD2 1 ? 
ATOM   805  C CE1 . PHE   A 1 103 ? 8.857   6.541   35.970 1.000 16.328 0 103 PHE   A CE1 1 ? 
ATOM   806  C CE2 . PHE   A 1 103 ? 7.955   8.750   36.061 1.000 16.497 0 103 PHE   A CE2 1 ? 
ATOM   807  C CZ  . PHE   A 1 103 ? 7.970   7.442   36.513 1.000 16.996 0 103 PHE   A CZ  1 ? 
ATOM   808  N N   . VAL   A 1 104 ? 12.803  7.595   30.951 1.000 22.605 0 104 VAL   A N   1 ? 
ATOM   809  C CA  . VAL   A 1 104 ? 13.515  8.099   29.791 1.000 22.242 0 104 VAL   A CA  1 ? 
ATOM   810  C C   . VAL   A 1 104 ? 12.612  8.031   28.570 1.000 21.057 0 104 VAL   A C   1 ? 
ATOM   811  O O   . VAL   A 1 104 ? 11.725  7.188   28.466 1.000 21.388 0 104 VAL   A O   1 ? 
ATOM   812  C CB  . VAL   A 1 104 ? 14.840  7.359   29.538 1.000 24.029 0 104 VAL   A CB  1 ? 
ATOM   813  C CG1 . VAL   A 1 104 ? 15.683  7.286   30.802 1.000 25.922 0 104 VAL   A CG1 1 ? 
ATOM   814  C CG2 . VAL   A 1 104 ? 14.614  5.980   28.970 1.000 24.554 0 104 VAL   A CG2 1 ? 
ATOM   815  N N   . ARG   A 1 105 ? 12.901  8.929   27.635 1.000 18.069 0 105 ARG   A N   1 ? 
ATOM   816  C CA  . ARG   A 1 105 ? 12.288  8.905   26.330 1.000 19.023 0 105 ARG   A CA  1 ? 
ATOM   817  C C   . ARG   A 1 105 ? 13.314  8.305   25.367 1.000 21.234 0 105 ARG   A C   1 ? 
ATOM   818  O O   . ARG   A 1 105 ? 14.442  8.814   25.253 1.000 19.250 0 105 ARG   A O   1 ? 
ATOM   819  C CB  . ARG   A 1 105 ? 11.851  10.326  25.959 1.000 18.883 0 105 ARG   A CB  1 ? 
ATOM   820  C CG  . ARG   A 1 105 ? 11.061  10.381  24.664 1.000 19.008 0 105 ARG   A CG  1 ? 
ATOM   821  C CD  . ARG   A 1 105 ? 10.447  11.734  24.408 1.000 18.383 0 105 ARG   A CD  1 ? 
ATOM   822  N NE  . ARG   A 1 105 ? 9.679   11.677  23.174 1.000 17.859 0 105 ARG   A NE  1 ? 
ATOM   823  C CZ  . ARG   A 1 105 ? 8.381   11.433  23.095 1.000 18.458 0 105 ARG   A CZ  1 ? 
ATOM   824  N NH1 . ARG   A 1 105 ? 7.714   11.008  24.155 1.000 20.006 0 105 ARG   A NH1 1 ? 
ATOM   825  N NH2 . ARG   A 1 105 ? 7.759   11.555  21.938 1.000 18.743 0 105 ARG   A NH2 1 ? 
ATOM   826  N N   . ILE   A 1 106 ? 12.942  7.202   24.701 1.000 20.016 0 106 ILE   A N   1 ? 
ATOM   827  C CA  . ILE   A 1 106 ? 13.881  6.592   23.772 1.000 22.653 0 106 ILE   A CA  1 ? 
ATOM   828  C C   . ILE   A 1 106 ? 13.670  7.136   22.356 1.000 23.593 0 106 ILE   A C   1 ? 
ATOM   829  O O   . ILE   A 1 106 ? 12.670  7.799   22.080 1.000 21.507 0 106 ILE   A O   1 ? 
ATOM   830  C CB  . ILE   A 1 106 ? 13.803  5.061   23.806 1.000 22.983 0 106 ILE   A CB  1 ? 
ATOM   831  C CG1 . ILE   A 1 106 ? 12.395  4.560   23.486 1.000 24.593 0 106 ILE   A CG1 1 ? 
ATOM   832  C CG2 . ILE   A 1 106 ? 14.341  4.522   25.127 1.000 23.770 0 106 ILE   A CG2 1 ? 
ATOM   833  C CD1 . ILE   A 1 106 ? 12.405  3.164   22.963 1.000 25.973 0 106 ILE   A CD1 1 ? 
ATOM   834  N N   . GLN   A 1 107 ? 14.624  6.786   21.484 1.000 23.835 0 107 GLN   A N   1 ? 
ATOM   835  C CA  . GLN   A 1 107 ? 14.659  7.175   20.083 1.000 25.515 0 107 GLN   A CA  1 ? 
ATOM   836  C C   . GLN   A 1 107 ? 14.254  5.996   19.202 1.000 23.193 0 107 GLN   A C   1 ? 
ATOM   837  O O   . GLN   A 1 107 ? 14.389  4.839   19.597 1.000 20.326 0 107 GLN   A O   1 ? 
ATOM   838  C CB  . GLN   A 1 107 ? 16.097  7.531   19.684 1.000 30.180 0 107 GLN   A CB  1 ? 
ATOM   839  C CG  . GLN   A 1 107 ? 16.839  8.404   20.689 1.000 38.024 0 107 GLN   A CG  1 ? 
ATOM   840  C CD  . GLN   A 1 107 ? 16.558  9.877   20.503 1.000 47.236 0 107 GLN   A CD  1 ? 
ATOM   841  O OE1 . GLN   A 1 107 ? 17.158  10.534  19.654 1.000 50.432 0 107 GLN   A OE1 1 ? 
ATOM   842  N NE2 . GLN   A 1 107 ? 15.678  10.422  21.331 1.000 52.686 0 107 GLN   A NE2 1 ? 
ATOM   843  N N   . PRO   A 1 108 ? 13.799  6.237   17.959 1.000 21.621 0 108 PRO   A N   1 ? 
ATOM   844  C CA  . PRO   A 1 108 ? 13.509  5.148   17.025 1.000 20.259 0 108 PRO   A CA  1 ? 
ATOM   845  C C   . PRO   A 1 108 ? 14.722  4.247   16.822 1.000 21.211 0 108 PRO   A C   1 ? 
ATOM   846  O O   . PRO   A 1 108 ? 15.846  4.729   16.704 1.000 19.318 0 108 PRO   A O   1 ? 
ATOM   847  C CB  . PRO   A 1 108 ? 13.174  5.858   15.715 1.000 20.708 0 108 PRO   A CB  1 ? 
ATOM   848  C CG  . PRO   A 1 108 ? 12.725  7.226   16.142 1.000 23.263 0 108 PRO   A CG  1 ? 
ATOM   849  C CD  . PRO   A 1 108 ? 13.475  7.561   17.418 1.000 22.275 0 108 PRO   A CD  1 ? 
ATOM   850  N N   . GLY   A 1 109 ? 14.475  2.935   16.742 1.000 19.531 0 109 GLY   A N   1 ? 
ATOM   851  C CA  . GLY   A 1 109 ? 15.544  1.959   16.664 1.000 20.054 0 109 GLY   A CA  1 ? 
ATOM   852  C C   . GLY   A 1 109 ? 15.961  1.390   18.022 1.000 19.891 0 109 GLY   A C   1 ? 
ATOM   853  O O   . GLY   A 1 109 ? 16.528  0.307   18.077 1.000 19.398 0 109 GLY   A O   1 ? 
ATOM   854  N N   . GLN   A 1 110 ? 15.708  2.098   19.128 1.000 19.101 0 110 GLN   A N   1 ? 
ATOM   855  C CA  . GLN   A 1 110 ? 16.085  1.554   20.426 1.000 18.743 0 110 GLN   A CA  1 ? 
ATOM   856  C C   . GLN   A 1 110 ? 15.071  0.465   20.812 1.000 18.562 0 110 GLN   A C   1 ? 
ATOM   857  O O   . GLN   A 1 110 ? 13.905  0.450   20.362 1.000 17.050 0 110 GLN   A O   1 ? 
ATOM   858  C CB  . GLN   A 1 110 ? 16.220  2.662   21.480 1.000 21.453 0 110 GLN   A CB  1 ? 
ATOM   859  C CG  . GLN   A 1 110 ? 17.254  3.733   21.120 1.000 23.331 0 110 GLN   A CG  1 ? 
ATOM   860  C CD  . GLN   A 1 110 ? 17.626  4.684   22.248 1.000 26.070 0 110 GLN   A CD  1 ? 
ATOM   861  O OE1 . GLN   A 1 110 ? 16.865  5.541   22.689 1.000 24.328 0 110 GLN   A OE1 1 ? 
ATOM   862  N NE2 . GLN   A 1 110 ? 18.863  4.598   22.698 1.000 30.839 0 110 GLN   A NE2 1 ? 
ATOM   863  N N   . THR   A 1 111 ? 15.555  -0.495  21.601 1.000 17.199 0 111 THR   A N   1 ? 
ATOM   864  C CA  . THR   A 1 111 ? 14.753  -1.637  22.017 1.000 16.786 0 111 THR   A CA  1 ? 
ATOM   865  C C   . THR   A 1 111 ? 14.445  -1.568  23.508 1.000 15.873 0 111 THR   A C   1 ? 
ATOM   866  O O   . THR   A 1 111 ? 15.093  -0.846  24.284 1.000 17.348 0 111 THR   A O   1 ? 
ATOM   867  C CB  . THR   A 1 111 ? 15.465  -2.965  21.731 1.000 16.931 0 111 THR   A CB  1 ? 
ATOM   868  O OG1 . THR   A 1 111 ? 16.735  -2.906  22.379 1.000 16.653 0 111 THR   A OG1 1 ? 
ATOM   869  C CG2 . THR   A 1 111 ? 15.628  -3.231  20.252 1.000 17.676 0 111 THR   A CG2 1 ? 
ATOM   870  N N   . PHE   A 1 112 ? 13.448  -2.355  23.899 1.000 14.209 0 112 PHE   A N   1 ? 
ATOM   871  C CA  . PHE   A 1 112 ? 13.013  -2.401  25.282 1.000 13.022 0 112 PHE   A CA  1 ? 
ATOM   872  C C   . PHE   A 1 112 ? 12.147  -3.635  25.484 1.000 12.355 0 112 PHE   A C   1 ? 
ATOM   873  O O   . PHE   A 1 112 ? 11.592  -4.181  24.528 1.000 11.688 0 112 PHE   A O   1 ? 
ATOM   874  C CB  . PHE   A 1 112 ? 12.289  -1.119  25.691 1.000 12.564 0 112 PHE   A CB  1 ? 
ATOM   875  C CG  . PHE   A 1 112 ? 11.040  -0.800  24.919 1.000 13.676 0 112 PHE   A CG  1 ? 
ATOM   876  C CD1 . PHE   A 1 112 ? 9.814   -1.295  25.319 1.000 13.221 0 112 PHE   A CD1 1 ? 
ATOM   877  C CD2 . PHE   A 1 112 ? 11.095  -0.032  23.764 1.000 15.977 0 112 PHE   A CD2 1 ? 
ATOM   878  C CE1 . PHE   A 1 112 ? 8.663   -0.981  24.623 1.000 14.096 0 112 PHE   A CE1 1 ? 
ATOM   879  C CE2 . PHE   A 1 112 ? 9.940   0.256   23.042 1.000 16.513 0 112 PHE   A CE2 1 ? 
ATOM   880  C CZ  . PHE   A 1 112 ? 8.719   -0.183  23.498 1.000 15.213 0 112 PHE   A CZ  1 ? 
ATOM   881  N N   . SER   A 1 113 ? 12.063  -4.062  26.732 1.000 11.299 0 113 SER   A N   1 ? 
ATOM   882  C CA  . SER   A 1 113 ? 11.220  -5.185  27.091 1.000 12.449 0 113 SER   A CA  1 ? 
ATOM   883  C C   . SER   A 1 113 ? 9.853   -4.679  27.523 1.000 11.672 0 113 SER   A C   1 ? 
ATOM   884  O O   . SER   A 1 113 ? 9.743   -3.688  28.229 1.000 11.031 0 113 SER   A O   1 ? 
ATOM   885  C CB  . SER   A 1 113 ? 11.828  -6.009  28.211 1.000 12.999 0 113 SER   A CB  1 ? 
ATOM   886  O OG  . SER   A 1 113 ? 13.078  -6.518  27.830 1.000 14.851 0 113 SER   A OG  1 ? 
ATOM   887  N N   . VAL   A 1 114 ? 8.835   -5.464  27.190 1.000 11.829 0 114 VAL   A N   1 ? 
ATOM   888  C CA  . VAL   A 1 114 ? 7.476   -5.186  27.570 1.000 11.924 0 114 VAL   A CA  1 ? 
ATOM   889  C C   . VAL   A 1 114 ? 6.999   -6.256  28.543 1.000 12.179 0 114 VAL   A C   1 ? 
ATOM   890  O O   . VAL   A 1 114 ? 7.052   -7.454  28.236 1.000 11.368 0 114 VAL   A O   1 ? 
ATOM   891  C CB  . VAL   A 1 114 ? 6.559   -5.117  26.337 1.000 12.598 0 114 VAL   A CB  1 ? 
ATOM   892  C CG1 . VAL   A 1 114 ? 5.097   -5.103  26.760 1.000 12.788 0 114 VAL   A CG1 1 ? 
ATOM   893  C CG2 . VAL   A 1 114 ? 6.859   -3.894  25.488 1.000 12.915 0 114 VAL   A CG2 1 ? 
ATOM   894  N N   . LEU   A 1 115 ? 6.478   -5.803  29.697 1.000 12.485 0 115 LEU   A N   1 ? 
ATOM   895  C CA  . LEU   A 1 115 ? 5.722   -6.683  30.577 1.000 13.237 0 115 LEU   A CA  1 ? 
ATOM   896  C C   . LEU   A 1 115 ? 4.224   -6.474  30.356 1.000 13.429 0 115 LEU   A C   1 ? 
ATOM   897  O O   . LEU   A 1 115 ? 3.602   -5.565  30.882 1.000 14.391 0 115 LEU   A O   1 ? 
ATOM   898  C CB  . LEU   A 1 115 ? 6.137   -6.437  32.032 1.000 13.639 0 115 LEU   A CB  1 ? 
ATOM   899  C CG  . LEU   A 1 115 ? 5.415   -7.305  33.059 1.000 14.342 0 115 LEU   A CG  1 ? 
ATOM   900  C CD1 . LEU   A 1 115 ? 5.809   -8.760  32.877 1.000 14.690 0 115 LEU   A CD1 1 ? 
ATOM   901  C CD2 . LEU   A 1 115 ? 5.713   -6.847  34.484 1.000 15.185 0 115 LEU   A CD2 1 ? 
ATOM   902  N N   . ALA   A 1 116 ? 3.631   -7.364  29.579 1.000 15.357 0 116 ALA   A N   1 ? 
ATOM   903  C CA  . ALA   A 1 116 ? 2.213   -7.315  29.290 1.000 15.300 0 116 ALA   A CA  1 ? 
ATOM   904  C C   . ALA   A 1 116 ? 1.439   -7.725  30.542 1.000 16.319 0 116 ALA   A C   1 ? 
ATOM   905  O O   . ALA   A 1 116 ? 1.685   -8.801  31.085 1.000 17.352 0 116 ALA   A O   1 ? 
ATOM   906  C CB  . ALA   A 1 116 ? 1.938   -8.214  28.108 1.000 15.150 0 116 ALA   A CB  1 ? 
ATOM   907  N N   . CYS   A 1 117 ? 0.522   -6.857  31.001 1.000 16.640 0 117 CYS   A N   1 ? 
ATOM   908  C CA  . CYS   A 1 117 ? -0.299  -7.106  32.175 1.000 17.588 0 117 CYS   A CA  1 ? 
ATOM   909  C C   . CYS   A 1 117 ? -1.782  -6.977  31.872 1.000 15.719 0 117 CYS   A C   1 ? 
ATOM   910  O O   . CYS   A 1 117 ? -2.166  -6.253  30.985 1.000 16.167 0 117 CYS   A O   1 ? 
ATOM   911  C CB  . CYS   A 1 117 ? 0.027   -6.119  33.281 1.000 20.816 0 117 CYS   A CB  1 ? 
ATOM   912  S SG  . CYS   A 1 117 ? 1.760   -6.251  33.750 1.000 26.822 0 117 CYS   A SG  1 ? 
ATOM   913  N N   . TYR   A 1 118 ? -2.586  -7.722  32.623 1.000 17.002 0 118 TYR   A N   1 ? 
ATOM   914  C CA  . TYR   A 1 118 ? -4.041  -7.695  32.577 1.000 17.508 0 118 TYR   A CA  1 ? 
ATOM   915  C C   . TYR   A 1 118 ? -4.552  -7.685  34.016 1.000 18.596 0 118 TYR   A C   1 ? 
ATOM   916  O O   . TYR   A 1 118 ? -4.143  -8.533  34.804 1.000 19.943 0 118 TYR   A O   1 ? 
ATOM   917  C CB  . TYR   A 1 118 ? -4.591  -8.904  31.800 1.000 18.598 0 118 TYR   A CB  1 ? 
ATOM   918  C CG  . TYR   A 1 118 ? -4.153  -8.858  30.344 1.000 19.232 0 118 TYR   A CG  1 ? 
ATOM   919  C CD1 . TYR   A 1 118 ? -2.943  -9.423  29.938 1.000 19.161 0 118 TYR   A CD1 1 ? 
ATOM   920  C CD2 . TYR   A 1 118 ? -4.886  -8.122  29.407 1.000 18.206 0 118 TYR   A CD2 1 ? 
ATOM   921  C CE1 . TYR   A 1 118 ? -2.489  -9.296  28.629 1.000 18.490 0 118 TYR   A CE1 1 ? 
ATOM   922  C CE2 . TYR   A 1 118 ? -4.449  -7.998  28.101 1.000 17.210 0 118 TYR   A CE2 1 ? 
ATOM   923  C CZ  . TYR   A 1 118 ? -3.246  -8.575  27.716 1.000 18.147 0 118 TYR   A CZ  1 ? 
ATOM   924  O OH  . TYR   A 1 118 ? -2.823  -8.431  26.425 1.000 17.388 0 118 TYR   A OH  1 ? 
ATOM   925  N N   . ASN   A 1 119 ? -5.393  -6.698  34.364 1.000 20.990 0 119 ASN   A N   1 ? 
ATOM   926  C CA  . ASN   A 1 119 ? -5.934  -6.544  35.717 1.000 22.869 0 119 ASN   A CA  1 ? 
ATOM   927  C C   . ASN   A 1 119 ? -4.829  -6.475  36.775 1.000 21.198 0 119 ASN   A C   1 ? 
ATOM   928  O O   . ASN   A 1 119 ? -4.978  -7.042  37.858 1.000 19.372 0 119 ASN   A O   1 ? 
ATOM   929  C CB  . ASN   A 1 119 ? -6.875  -7.702  36.083 1.000 25.530 0 119 ASN   A CB  1 ? 
ATOM   930  C CG  . ASN   A 1 119 ? -7.965  -7.891  35.054 1.000 26.718 0 119 ASN   A CG  1 ? 
ATOM   931  O OD1 . ASN   A 1 119 ? -8.079  -8.950  34.453 1.000 31.772 0 119 ASN   A OD1 1 ? 
ATOM   932  N ND2 . ASN   A 1 119 ? -8.721  -6.848  34.787 1.000 30.038 0 119 ASN   A ND2 1 ? 
ATOM   933  N N   . GLY   A 1 120 ? -3.702  -5.835  36.441 1.000 19.304 0 120 GLY   A N   1 ? 
ATOM   934  C CA  . GLY   A 1 120 ? -2.645  -5.582  37.404 1.000 19.352 0 120 GLY   A CA  1 ? 
ATOM   935  C C   . GLY   A 1 120 ? -1.747  -6.791  37.644 1.000 21.219 0 120 GLY   A C   1 ? 
ATOM   936  O O   . GLY   A 1 120 ? -0.896  -6.740  38.536 1.000 22.092 0 120 GLY   A O   1 ? 
ATOM   937  N N   . SER   A 1 121 ? -1.977  -7.883  36.887 1.000 23.246 0 121 SER   A N   1 ? 
ATOM   938  C CA  . SER   A 1 121 ? -1.225  -9.127  37.039 1.000 25.488 0 121 SER   A CA  1 ? 
ATOM   939  C C   . SER   A 1 121 ? -0.360  -9.382  35.800 1.000 23.090 0 121 SER   A C   1 ? 
ATOM   940  O O   . SER   A 1 121 ? -0.862  -9.360  34.677 1.000 20.353 0 121 SER   A O   1 ? 
ATOM   941  C CB  . SER   A 1 121 ? -2.146  -10.293 37.287 1.000 28.257 0 121 SER   A CB  1 ? 
ATOM   942  O OG  . SER   A 1 121 ? -3.017  -10.024 38.382 1.000 33.679 0 121 SER   A OG  1 ? 
ATOM   943  N N   . PRO   A 1 122 ? 0.972   -9.553  35.954 1.000 23.859 0 122 PRO   A N   1 ? 
ATOM   944  C CA  . PRO   A 1 122 ? 1.853   -9.853  34.823 1.000 24.346 0 122 PRO   A CA  1 ? 
ATOM   945  C C   . PRO   A 1 122 ? 1.498   -11.156 34.116 1.000 24.911 0 122 PRO   A C   1 ? 
ATOM   946  O O   . PRO   A 1 122 ? 1.232   -12.173 34.751 1.000 25.113 0 122 PRO   A O   1 ? 
ATOM   947  C CB  . PRO   A 1 122 ? 3.244   -9.959  35.452 1.000 25.996 0 122 PRO   A CB  1 ? 
ATOM   948  C CG  . PRO   A 1 122 ? 3.144   -9.130  36.721 1.000 26.208 0 122 PRO   A CG  1 ? 
ATOM   949  C CD  . PRO   A 1 122 ? 1.724   -9.356  37.203 1.000 25.724 0 122 PRO   A CD  1 ? 
ATOM   950  N N   . SER   A 1 123 ? 1.497   -11.095 32.785 1.000 23.876 0 123 SER   A N   1 ? 
ATOM   951  C CA  . SER   A 1 123 ? 1.072   -12.196 31.946 1.000 22.684 0 123 SER   A CA  1 ? 
ATOM   952  C C   . SER   A 1 123 ? 2.219   -12.689 31.054 1.000 21.282 0 123 SER   A C   1 ? 
ATOM   953  O O   . SER   A 1 123 ? 2.296   -13.870 30.756 1.000 20.235 0 123 SER   A O   1 ? 
ATOM   954  C CB  . SER   A 1 123 ? -0.120  -11.766 31.154 1.000 24.047 0 123 SER   A CB  1 ? 
ATOM   955  O OG  . SER   A 1 123 ? -0.186  -12.451 29.916 1.000 29.679 0 123 SER   A OG  1 ? 
ATOM   956  N N   . GLY   A 1 124 ? 3.130   -11.808 30.624 1.000 18.672 0 124 GLY   A N   1 ? 
ATOM   957  C CA  . GLY   A 1 124 ? 4.127   -12.212 29.653 1.000 17.085 0 124 GLY   A CA  1 ? 
ATOM   958  C C   . GLY   A 1 124 ? 5.159   -11.118 29.436 1.000 16.974 0 124 GLY   A C   1 ? 
ATOM   959  O O   . GLY   A 1 124 ? 4.844   -9.967  29.681 1.000 15.882 0 124 GLY   A O   1 ? 
ATOM   960  N N   . VAL   A 1 125 ? 6.346   -11.495 28.930 1.000 16.560 0 125 VAL   A N   1 ? 
ATOM   961  C CA  . VAL   A 1 125 ? 7.412   -10.543 28.675 1.000 17.244 0 125 VAL   A CA  1 ? 
ATOM   962  C C   . VAL   A 1 125 ? 7.985   -10.817 27.295 1.000 16.164 0 125 VAL   A C   1 ? 
ATOM   963  O O   . VAL   A 1 125 ? 8.234   -11.969 26.954 1.000 15.255 0 125 VAL   A O   1 ? 
ATOM   964  C CB  . VAL   A 1 125 ? 8.501   -10.575 29.767 1.000 19.895 0 125 VAL   A CB  1 ? 
ATOM   965  C CG1 . VAL   A 1 125 ? 9.392   -11.780 29.676 1.000 23.631 0 125 VAL   A CG1 1 ? 
ATOM   966  C CG2 . VAL   A 1 125 ? 9.348   -9.327  29.762 1.000 21.831 0 125 VAL   A CG2 1 ? 
ATOM   967  N N   . TYR   A 1 126 ? 8.199   -9.730  26.524 1.000 16.071 0 126 TYR   A N   1 ? 
ATOM   968  C CA  . TYR   A 1 126 ? 8.845   -9.822  25.232 1.000 15.404 0 126 TYR   A CA  1 ? 
ATOM   969  C C   . TYR   A 1 126 ? 9.613   -8.537  24.937 1.000 16.381 0 126 TYR   A C   1 ? 
ATOM   970  O O   . TYR   A 1 126 ? 9.381   -7.479  25.517 1.000 15.252 0 126 TYR   A O   1 ? 
ATOM   971  C CB  . TYR   A 1 126 ? 7.757   -10.145 24.204 1.000 16.100 0 126 TYR   A CB  1 ? 
ATOM   972  C CG  . TYR   A 1 126 ? 6.607   -9.148  24.115 1.000 16.929 0 126 TYR   A CG  1 ? 
ATOM   973  C CD1 . TYR   A 1 126 ? 6.702   -7.996  23.356 1.000 17.264 0 126 TYR   A CD1 1 ? 
ATOM   974  C CD2 . TYR   A 1 126 ? 5.427   -9.355  24.817 1.000 17.891 0 126 TYR   A CD2 1 ? 
ATOM   975  C CE1 . TYR   A 1 126 ? 5.653   -7.085  23.299 1.000 18.812 0 126 TYR   A CE1 1 ? 
ATOM   976  C CE2 . TYR   A 1 126 ? 4.366   -8.471  24.747 1.000 18.381 0 126 TYR   A CE2 1 ? 
ATOM   977  C CZ  . TYR   A 1 126 ? 4.485   -7.322  23.989 1.000 18.832 0 126 TYR   A CZ  1 ? 
ATOM   978  O OH  . TYR   A 1 126 ? 3.442   -6.447  23.923 1.000 20.531 0 126 TYR   A OH  1 ? 
ATOM   979  N N   . GLN   A 1 127 ? 10.526  -8.663  23.988 1.000 16.175 0 127 GLN   A N   1 ? 
ATOM   980  C CA  . GLN   A 1 127 ? 11.357  -7.590  23.497 1.000 18.544 0 127 GLN   A CA  1 ? 
ATOM   981  C C   . GLN   A 1 127 ? 10.692  -6.959  22.271 1.000 19.338 0 127 GLN   A C   1 ? 
ATOM   982  O O   . GLN   A 1 127 ? 10.125  -7.659  21.425 1.000 18.651 0 127 GLN   A O   1 ? 
ATOM   983  C CB  . GLN   A 1 127 ? 12.691  -8.269  23.201 1.000 20.655 0 127 GLN   A CB  1 ? 
ATOM   984  C CG  . GLN   A 1 127 ? 13.825  -7.346  22.829 1.000 22.978 0 127 GLN   A CG  1 ? 
ATOM   985  C CD  . GLN   A 1 127 ? 14.434  -6.636  24.004 1.000 22.431 0 127 GLN   A CD  1 ? 
ATOM   986  O OE1 . GLN   A 1 127 ? 15.455  -5.965  23.850 1.000 26.485 0 127 GLN   A OE1 1 ? 
ATOM   987  N NE2 . GLN   A 1 127 ? 13.823  -6.778  25.174 1.000 21.545 0 127 GLN   A NE2 1 ? 
ATOM   988  N N   . CYS   A 1 128 ? 10.709  -5.629  22.187 1.000 20.710 0 128 CYS   A N   1 ? 
ATOM   989  C CA  . CYS   A 1 128 ? 10.556  -4.989  20.888 1.000 23.958 0 128 CYS   A CA  1 ? 
ATOM   990  C C   . CYS   A 1 128 ? 11.308  -3.672  20.795 1.000 21.998 0 128 CYS   A C   1 ? 
ATOM   991  O O   . CYS   A 1 128 ? 12.108  -3.345  21.649 1.000 24.670 0 128 CYS   A O   1 ? 
ATOM   992  C CB  . CYS   A 1 128 ? 9.098   -4.821  20.509 1.000 29.480 0 128 CYS   A CB  1 ? 
ATOM   993  S SG  . CYS   A 1 128 ? 8.091   -4.238  21.876 1.000 34.765 0 128 CYS   A SG  1 ? 
ATOM   994  N N   . ALA   A 1 129 ? 11.108  -2.990  19.668 1.000 21.268 0 129 ALA   A N   1 ? 
ATOM   995  C CA  . ALA   A 1 129 ? 11.806  -1.779  19.324 1.000 18.354 0 129 ALA   A CA  1 ? 
ATOM   996  C C   . ALA   A 1 129 ? 10.801  -0.704  18.940 1.000 17.582 0 129 ALA   A C   1 ? 
ATOM   997  O O   . ALA   A 1 129 ? 9.705   -0.984  18.465 1.000 16.201 0 129 ALA   A O   1 ? 
ATOM   998  C CB  . ALA   A 1 129 ? 12.759  -2.054  18.188 1.000 19.415 0 129 ALA   A CB  1 ? 
ATOM   999  N N   . MET   A 1 130 ? 11.206  0.533   19.201 1.000 15.888 0 130 MET   A N   1 ? 
ATOM   1000 C CA  . MET   A 1 130 ? 10.494  1.702   18.761 1.000 14.825 0 130 MET   A CA  1 ? 
ATOM   1001 C C   . MET   A 1 130 ? 10.756  1.787   17.264 1.000 14.629 0 130 MET   A C   1 ? 
ATOM   1002 O O   . MET   A 1 130 ? 11.901  1.919   16.849 1.000 14.900 0 130 MET   A O   1 ? 
ATOM   1003 C CB  . MET   A 1 130 ? 11.058  2.930   19.485 1.000 16.120 0 130 MET   A CB  1 ? 
ATOM   1004 C CG  . MET   A 1 130 ? 10.380  4.265   19.136 1.000 16.958 0 130 MET   A CG  1 ? 
ATOM   1005 S SD  . MET   A 1 130 ? 8.637   4.148   19.406 1.000 17.674 0 130 MET   A SD  1 ? 
ATOM   1006 C CE  . MET   A 1 130 ? 8.560   4.043   21.198 1.000 20.103 0 130 MET   A CE  1 ? 
ATOM   1007 N N   . ARG   A 1 131 ? 9.727   1.582   16.452 1.000 13.523 0 131 ARG   A N   1 ? 
ATOM   1008 C CA  . ARG   A 1 131 ? 9.918   1.607   15.015 1.000 14.142 0 131 ARG   A CA  1 ? 
ATOM   1009 C C   . ARG   A 1 131 ? 10.185  3.042   14.559 1.000 13.790 0 131 ARG   A C   1 ? 
ATOM   1010 O O   . ARG   A 1 131 ? 9.864   4.001   15.255 1.000 13.271 0 131 ARG   A O   1 ? 
ATOM   1011 C CB  . ARG   A 1 131 ? 8.689   1.073   14.280 1.000 15.095 0 131 ARG   A CB  1 ? 
ATOM   1012 C CG  . ARG   A 1 131 ? 8.217   -0.302  14.719 1.000 15.293 0 131 ARG   A CG  1 ? 
ATOM   1013 C CD  . ARG   A 1 131 ? 9.261   -1.362  14.541 1.000 15.840 0 131 ARG   A CD  1 ? 
ATOM   1014 N NE  . ARG   A 1 131 ? 9.765   -1.384  13.183 1.000 16.117 0 131 ARG   A NE  1 ? 
ATOM   1015 C CZ  . ARG   A 1 131 ? 10.844  -2.040  12.766 1.000 16.116 0 131 ARG   A CZ  1 ? 
ATOM   1016 N NH1 . ARG   A 1 131 ? 11.478  -2.884  13.565 1.000 14.949 0 131 ARG   A NH1 1 ? 
ATOM   1017 N NH2 . ARG   A 1 131 ? 11.277  -1.840  11.530 1.000 15.910 0 131 ARG   A NH2 1 ? 
ATOM   1018 N N   . PRO   A 1 132 ? 10.817  3.231   13.378 1.000 14.493 0 132 PRO   A N   1 ? 
ATOM   1019 C CA  . PRO   A 1 132 ? 11.021  4.579   12.839 1.000 14.727 0 132 PRO   A CA  1 ? 
ATOM   1020 C C   . PRO   A 1 132 ? 9.757   5.417   12.643 1.000 14.667 0 132 PRO   A C   1 ? 
ATOM   1021 O O   . PRO   A 1 132 ? 9.818   6.632   12.780 1.000 15.431 0 132 PRO   A O   1 ? 
ATOM   1022 C CB  . PRO   A 1 132 ? 11.775  4.352   11.535 1.000 14.887 0 132 PRO   A CB  1 ? 
ATOM   1023 C CG  . PRO   A 1 132 ? 12.477  2.999   11.776 1.000 15.383 0 132 PRO   A CG  1 ? 
ATOM   1024 C CD  . PRO   A 1 132 ? 11.507  2.177   12.599 1.000 13.881 0 132 PRO   A CD  1 ? 
ATOM   1025 N N   . ASN   A 1 133 ? 8.610   4.769   12.451 1.000 13.917 0 133 ASN   A N   1 ? 
ATOM   1026 C CA  . ASN   A 1 133 ? 7.331   5.452   12.395 1.000 14.269 0 133 ASN   A CA  1 ? 
ATOM   1027 C C   . ASN   A 1 133 ? 6.668   5.624   13.774 1.000 15.921 0 133 ASN   A C   1 ? 
ATOM   1028 O O   . ASN   A 1 133 ? 5.502   6.007   13.835 1.000 16.127 0 133 ASN   A O   1 ? 
ATOM   1029 C CB  . ASN   A 1 133 ? 6.411   4.725   11.419 1.000 13.588 0 133 ASN   A CB  1 ? 
ATOM   1030 C CG  . ASN   A 1 133 ? 5.922   3.380   11.901 1.000 13.706 0 133 ASN   A CG  1 ? 
ATOM   1031 O OD1 . ASN   A 1 133 ? 6.267   2.921   13.000 1.000 13.953 0 133 ASN   A OD1 1 ? 
ATOM   1032 N ND2 . ASN   A 1 133 ? 5.090   2.757   11.082 1.000 13.607 0 133 ASN   A ND2 1 ? 
ATOM   1033 N N   . PHE   A 1 134 ? 7.383   5.307   14.870 1.000 17.603 0 134 PHE   A N   1 ? 
ATOM   1034 C CA  . PHE   A 1 134 ? 6.980   5.585   16.247 1.000 17.703 0 134 PHE   A CA  1 ? 
ATOM   1035 C C   . PHE   A 1 134 ? 5.845   4.662   16.719 1.000 17.406 0 134 PHE   A C   1 ? 
ATOM   1036 O O   . PHE   A 1 134 ? 5.127   4.950   17.696 1.000 18.962 0 134 PHE   A O   1 ? 
ATOM   1037 C CB  . PHE   A 1 134 ? 6.665   7.074   16.442 1.000 20.793 0 134 PHE   A CB  1 ? 
ATOM   1038 C CG  . PHE   A 1 134 ? 7.864   7.988   16.339 1.000 24.686 0 134 PHE   A CG  1 ? 
ATOM   1039 C CD1 . PHE   A 1 134 ? 8.844   7.985   17.325 1.000 27.828 0 134 PHE   A CD1 1 ? 
ATOM   1040 C CD2 . PHE   A 1 134 ? 8.012   8.851   15.256 1.000 28.704 0 134 PHE   A CD2 1 ? 
ATOM   1041 C CE1 . PHE   A 1 134 ? 9.944   8.826   17.237 1.000 30.296 0 134 PHE   A CE1 1 ? 
ATOM   1042 C CE2 . PHE   A 1 134 ? 9.118   9.688   15.161 1.000 30.154 0 134 PHE   A CE2 1 ? 
ATOM   1043 C CZ  . PHE   A 1 134 ? 10.083  9.669   16.150 1.000 31.239 0 134 PHE   A CZ  1 ? 
ATOM   1044 N N   . THR   A 1 135 ? 5.715   3.501   16.078 1.000 15.181 0 135 THR   A N   1 ? 
ATOM   1045 C CA  . THR   A 1 135 ? 4.859   2.453   16.589 1.000 13.802 0 135 THR   A CA  1 ? 
ATOM   1046 C C   . THR   A 1 135 ? 5.733   1.379   17.219 1.000 14.072 0 135 THR   A C   1 ? 
ATOM   1047 O O   . THR   A 1 135 ? 6.955   1.403   17.095 1.000 13.334 0 135 THR   A O   1 ? 
ATOM   1048 C CB  . THR   A 1 135 ? 3.958   1.933   15.473 1.000 13.747 0 135 THR   A CB  1 ? 
ATOM   1049 O OG1 . THR   A 1 135 ? 4.761   1.248   14.507 1.000 12.892 0 135 THR   A OG1 1 ? 
ATOM   1050 C CG2 . THR   A 1 135 ? 3.165   3.056   14.838 1.000 14.490 0 135 THR   A CG2 1 ? 
ATOM   1051 N N   . ILE   A 1 136 ? 5.097   0.445   17.913 1.000 14.571 0 136 ILE   A N   1 ? 
ATOM   1052 C CA  . ILE   A 1 136 ? 5.771   -0.772  18.310 1.000 16.871 0 136 ILE   A CA  1 ? 
ATOM   1053 C C   . ILE   A 1 136 ? 4.952   -1.969  17.813 1.000 18.074 0 136 ILE   A C   1 ? 
ATOM   1054 O O   . ILE   A 1 136 ? 3.726   -1.905  17.732 1.000 18.320 0 136 ILE   A O   1 ? 
ATOM   1055 C CB  . ILE   A 1 136 ? 6.018   -0.783  19.831 1.000 18.086 0 136 ILE   A CB  1 ? 
ATOM   1056 C CG1 . ILE   A 1 136 ? 4.747   -1.002  20.645 1.000 18.296 0 136 ILE   A CG1 1 ? 
ATOM   1057 C CG2 . ILE   A 1 136 ? 6.723   0.496   20.287 1.000 18.755 0 136 ILE   A CG2 1 ? 
ATOM   1058 C CD1 . ILE   A 1 136 ? 5.038   -1.262  22.115 1.000 19.058 0 136 ILE   A CD1 1 ? 
ATOM   1059 N N   . LYS   A 1 137 ? 5.642   -3.071  17.523 1.000 17.780 0 137 LYS   A N   1 ? 
ATOM   1060 C CA  . LYS   A 1 137 ? 5.000   -4.289  17.069 1.000 20.460 0 137 LYS   A CA  1 ? 
ATOM   1061 C C   . LYS   A 1 137 ? 4.849   -5.190  18.286 1.000 19.200 0 137 LYS   A C   1 ? 
ATOM   1062 O O   . LYS   A 1 137 ? 5.634   -6.093  18.537 1.000 17.278 0 137 LYS   A O   1 ? 
ATOM   1063 C CB  . LYS   A 1 137 ? 5.797   -4.865  15.897 1.000 24.403 0 137 LYS   A CB  1 ? 
ATOM   1064 C CG  . LYS   A 1 137 ? 5.998   -3.869  14.758 1.000 28.452 0 137 LYS   A CG  1 ? 
ATOM   1065 C CD  . LYS   A 1 137 ? 6.998   -4.271  13.692 1.000 36.581 0 137 LYS   A CD  1 ? 
ATOM   1066 C CE  . LYS   A 1 137 ? 6.477   -5.347  12.770 1.000 45.676 0 137 LYS   A CE  1 ? 
ATOM   1067 N NZ  . LYS   A 1 137 ? 5.160   -4.983  12.191 1.000 51.267 0 137 LYS   A NZ  1 ? 
ATOM   1068 N N   . GLY   A 1 138 ? 3.812   -4.896  19.066 1.000 19.305 0 138 GLY   A N   1 ? 
ATOM   1069 C CA  . GLY   A 1 138 ? 3.614   -5.560  20.332 1.000 18.342 0 138 GLY   A CA  1 ? 
ATOM   1070 C C   . GLY   A 1 138 ? 2.606   -6.693  20.216 1.000 16.653 0 138 GLY   A C   1 ? 
ATOM   1071 O O   . GLY   A 1 138 ? 2.182   -7.061  19.139 1.000 17.065 0 138 GLY   A O   1 ? 
ATOM   1072 N N   . SER   A 1 139 ? 2.237   -7.221  21.377 1.000 16.724 0 139 SER   A N   1 ? 
ATOM   1073 C CA  . SER   A 1 139 ? 1.160   -8.168  21.531 1.000 16.854 0 139 SER   A CA  1 ? 
ATOM   1074 C C   . SER   A 1 139 ? 0.301   -7.732  22.716 1.000 16.778 0 139 SER   A C   1 ? 
ATOM   1075 O O   . SER   A 1 139 ? 0.670   -7.957  23.854 1.000 16.216 0 139 SER   A O   1 ? 
ATOM   1076 C CB  . SER   A 1 139 ? 1.712   -9.553  21.711 1.000 16.128 0 139 SER   A CB  1 ? 
ATOM   1077 O OG  . SER   A 1 139 ? 0.647   -10.440 21.927 1.000 15.545 0 139 SER   A OG  1 ? 
ATOM   1078 N N   . PHE   A 1 140 ? -0.853  -7.116  22.423 1.000 17.122 0 140 PHE   A N   1 ? 
ATOM   1079 C CA  . PHE   A 1 140 ? -1.675  -6.458  23.419 1.000 16.433 0 140 PHE   A CA  1 ? 
ATOM   1080 C C   . PHE   A 1 140 ? -3.154  -6.672  23.101 1.000 17.222 0 140 PHE   A C   1 ? 
ATOM   1081 O O   . PHE   A 1 140 ? -3.589  -6.389  21.986 1.000 19.929 0 140 PHE   A O   1 ? 
ATOM   1082 C CB  . PHE   A 1 140 ? -1.396  -4.956  23.392 1.000 16.078 0 140 PHE   A CB  1 ? 
ATOM   1083 C CG  . PHE   A 1 140 ? -0.055  -4.498  23.895 1.000 14.630 0 140 PHE   A CG  1 ? 
ATOM   1084 C CD1 . PHE   A 1 140 ? 0.259   -4.555  25.241 1.000 14.883 0 140 PHE   A CD1 1 ? 
ATOM   1085 C CD2 . PHE   A 1 140 ? 0.865   -3.942  23.032 1.000 14.444 0 140 PHE   A CD2 1 ? 
ATOM   1086 C CE1 . PHE   A 1 140 ? 1.474   -4.077  25.706 1.000 14.834 0 140 PHE   A CE1 1 ? 
ATOM   1087 C CE2 . PHE   A 1 140 ? 2.081   -3.477  23.502 1.000 15.176 0 140 PHE   A CE2 1 ? 
ATOM   1088 C CZ  . PHE   A 1 140 ? 2.383   -3.544  24.837 1.000 14.314 0 140 PHE   A CZ  1 ? 
ATOM   1089 N N   . LEU   A 1 141 ? -3.900  -7.182  24.079 1.000 18.834 0 141 LEU   A N   1 ? 
ATOM   1090 C CA  . LEU   A 1 141 ? -5.353  -7.283  24.032 1.000 21.920 0 141 LEU   A CA  1 ? 
ATOM   1091 C C   . LEU   A 1 141 ? -5.994  -6.194  24.899 1.000 20.894 0 141 LEU   A C   1 ? 
ATOM   1092 O O   . LEU   A 1 141 ? -5.314  -5.407  25.551 1.000 17.998 0 141 LEU   A O   1 ? 
ATOM   1093 C CB  . LEU   A 1 141 ? -5.734  -8.670  24.557 1.000 21.866 0 141 LEU   A CB  1 ? 
ATOM   1094 C CG  . LEU   A 1 141 ? -5.100  -9.844  23.819 1.000 23.242 0 141 LEU   A CG  1 ? 
ATOM   1095 C CD1 . LEU   A 1 141 ? -5.336  -11.128 24.592 1.000 25.031 0 141 LEU   A CD1 1 ? 
ATOM   1096 C CD2 . LEU   A 1 141 ? -5.656  -9.969  22.405 1.000 22.380 0 141 LEU   A CD2 1 ? 
ATOM   1097 N N   . ASN   A 1 142 ? -7.330  -6.185  24.949 1.000 23.405 0 142 ASN   A N   1 ? 
ATOM   1098 C CA  . ASN   A 1 142 ? -8.057  -5.268  25.818 1.000 24.358 0 142 ASN   A CA  1 ? 
ATOM   1099 C C   . ASN   A 1 142 ? -7.737  -5.647  27.264 1.000 21.036 0 142 ASN   A C   1 ? 
ATOM   1100 O O   . ASN   A 1 142 ? -7.656  -6.834  27.577 1.000 21.885 0 142 ASN   A O   1 ? 
ATOM   1101 C CB  . ASN   A 1 142 ? -9.543  -5.250  25.444 1.000 27.584 0 142 ASN   A CB  1 ? 
ATOM   1102 C CG  . ASN   A 1 142 ? -10.321 -4.059  25.978 1.000 31.713 0 142 ASN   A CG  1 ? 
ATOM   1103 O OD1 . ASN   A 1 142 ? -11.501 -4.204  26.300 1.000 34.147 0 142 ASN   A OD1 1 ? 
ATOM   1104 N ND2 . ASN   A 1 142 ? -9.711  -2.881  26.035 1.000 31.779 0 142 ASN   A ND2 1 ? 
ATOM   1105 N N   . GLY   A 1 143 ? -7.520  -4.635  28.118 1.000 18.818 0 143 GLY   A N   1 ? 
ATOM   1106 C CA  . GLY   A 1 143 ? -6.985  -4.838  29.457 1.000 18.491 0 143 GLY   A CA  1 ? 
ATOM   1107 C C   . GLY   A 1 143 ? -5.482  -4.562  29.585 1.000 19.481 0 143 GLY   A C   1 ? 
ATOM   1108 O O   . GLY   A 1 143 ? -4.952  -4.470  30.697 1.000 19.375 0 143 GLY   A O   1 ? 
ATOM   1109 N N   . SER   A 1 144 ? -4.756  -4.438  28.468 1.000 16.910 0 144 SER   A N   1 ? 
ATOM   1110 C CA  . SER   A 1 144 ? -3.305  -4.377  28.588 1.000 15.813 0 144 SER   A CA  1 ? 
ATOM   1111 C C   . SER   A 1 144 ? -2.806  -2.957  28.858 1.000 14.694 0 144 SER   A C   1 ? 
ATOM   1112 O O   . SER   A 1 144 ? -1.648  -2.764  29.245 1.000 12.715 0 144 SER   A O   1 ? 
ATOM   1113 C CB  . SER   A 1 144 ? -2.633  -4.967  27.376 1.000 14.405 0 144 SER   A CB  1 ? 
ATOM   1114 O OG  . SER   A 1 144 ? -2.990  -4.277  26.191 1.000 14.432 0 144 SER   A OG  1 ? 
ATOM   1115 N N   . CYS   A 1 145 ? -3.651  -1.966  28.567 1.000 13.515 0 145 CYS   A N   1 ? 
ATOM   1116 C CA  . CYS   A 1 145 ? -3.260  -0.582  28.731 1.000 13.825 0 145 CYS   A CA  1 ? 
ATOM   1117 C C   . CYS   A 1 145 ? -2.658  -0.375  30.120 1.000 13.286 0 145 CYS   A C   1 ? 
ATOM   1118 O O   . CYS   A 1 145 ? -3.151  -0.925  31.111 1.000 11.400 0 145 CYS   A O   1 ? 
ATOM   1119 C CB  . CYS   A 1 145 ? -4.431  0.362   28.522 1.000 14.836 0 145 CYS   A CB  1 ? 
ATOM   1120 S SG  . CYS   A 1 145 ? -4.848  0.580   26.772 1.000 18.843 0 145 CYS   A SG  1 ? 
ATOM   1121 N N   . GLY   A 1 146 ? -1.560  0.396   30.146 1.000 12.699 0 146 GLY   A N   1 ? 
ATOM   1122 C CA  . GLY   A 1 146 ? -0.808  0.672   31.356 1.000 11.914 0 146 GLY   A CA  1 ? 
ATOM   1123 C C   . GLY   A 1 146 ? 0.347   -0.307  31.550 1.000 12.437 0 146 GLY   A C   1 ? 
ATOM   1124 O O   . GLY   A 1 146 ? 1.132   -0.126  32.490 1.000 12.087 0 146 GLY   A O   1 ? 
ATOM   1125 N N   . SER   A 1 147 ? 0.423   -1.349  30.689 1.000 11.816 0 147 SER   A N   1 ? 
ATOM   1126 C CA  . SER   A 1 147 ? 1.608   -2.180  30.598 1.000 11.561 0 147 SER   A CA  1 ? 
ATOM   1127 C C   . SER   A 1 147 ? 2.778   -1.294  30.203 1.000 11.906 0 147 SER   A C   1 ? 
ATOM   1128 O O   . SER   A 1 147 ? 2.592   -0.354  29.423 1.000 12.384 0 147 SER   A O   1 ? 
ATOM   1129 C CB  . SER   A 1 147 ? 1.437   -3.333  29.620 1.000 11.621 0 147 SER   A CB  1 ? 
ATOM   1130 O OG  . SER   A 1 147 ? 0.466   -4.257  30.085 1.000 11.588 0 147 SER   A OG  1 ? 
ATOM   1131 N N   . VAL   A 1 148 ? 3.968   -1.593  30.739 1.000 11.871 0 148 VAL   A N   1 ? 
ATOM   1132 C CA  . VAL   A 1 148 ? 5.112   -0.732  30.505 1.000 12.480 0 148 VAL   A CA  1 ? 
ATOM   1133 C C   . VAL   A 1 148 ? 6.235   -1.480  29.782 1.000 13.087 0 148 VAL   A C   1 ? 
ATOM   1134 O O   . VAL   A 1 148 ? 6.342   -2.709  29.812 1.000 13.927 0 148 VAL   A O   1 ? 
ATOM   1135 C CB  . VAL   A 1 148 ? 5.611   -0.061  31.800 1.000 12.969 0 148 VAL   A CB  1 ? 
ATOM   1136 C CG1 . VAL   A 1 148 ? 4.580   0.910   32.334 1.000 12.710 0 148 VAL   A CG1 1 ? 
ATOM   1137 C CG2 . VAL   A 1 148 ? 6.025   -1.048  32.888 1.000 13.513 0 148 VAL   A CG2 1 ? 
ATOM   1138 N N   . GLY   A 1 149 ? 7.046   -0.672  29.101 1.000 12.583 0 149 GLY   A N   1 ? 
ATOM   1139 C CA  . GLY   A 1 149 ? 8.304   -1.077  28.533 1.000 12.772 0 149 GLY   A CA  1 ? 
ATOM   1140 C C   . GLY   A 1 149 ? 9.450   -0.451  29.317 1.000 13.497 0 149 GLY   A C   1 ? 
ATOM   1141 O O   . GLY   A 1 149 ? 9.311   0.636   29.893 1.000 12.894 0 149 GLY   A O   1 ? 
ATOM   1142 N N   . PHE   A 1 150 ? 10.576  -1.160  29.324 1.000 12.760 0 150 PHE   A N   1 ? 
ATOM   1143 C CA  . PHE   A 1 150 ? 11.679  -0.793  30.181 1.000 14.599 0 150 PHE   A CA  1 ? 
ATOM   1144 C C   . PHE   A 1 150 ? 12.971  -1.446  29.693 1.000 15.653 0 150 PHE   A C   1 ? 
ATOM   1145 O O   . PHE   A 1 150 ? 12.973  -2.432  28.930 1.000 13.713 0 150 PHE   A O   1 ? 
ATOM   1146 C CB  . PHE   A 1 150 ? 11.370  -1.210  31.626 1.000 15.599 0 150 PHE   A CB  1 ? 
ATOM   1147 C CG  . PHE   A 1 150 ? 11.266  -2.704  31.812 1.000 16.064 0 150 PHE   A CG  1 ? 
ATOM   1148 C CD1 . PHE   A 1 150 ? 10.116  -3.384  31.450 1.000 16.472 0 150 PHE   A CD1 1 ? 
ATOM   1149 C CD2 . PHE   A 1 150 ? 12.347  -3.438  32.275 1.000 17.432 0 150 PHE   A CD2 1 ? 
ATOM   1150 C CE1 . PHE   A 1 150 ? 10.036  -4.763  31.583 1.000 16.732 0 150 PHE   A CE1 1 ? 
ATOM   1151 C CE2 . PHE   A 1 150 ? 12.271  -4.817  32.405 1.000 17.799 0 150 PHE   A CE2 1 ? 
ATOM   1152 C CZ  . PHE   A 1 150 ? 11.123  -5.480  32.028 1.000 17.935 0 150 PHE   A CZ  1 ? 
ATOM   1153 N N   . ASN   A 1 151 ? 14.060  -0.853  30.180 1.000 16.583 0 151 ASN   A N   1 ? 
ATOM   1154 C CA  . ASN   A 1 151 ? 15.394  -1.436  30.160 1.000 19.465 0 151 ASN   A CA  1 ? 
ATOM   1155 C C   . ASN   A 1 151 ? 15.895  -1.498  31.603 1.000 20.643 0 151 ASN   A C   1 ? 
ATOM   1156 O O   . ASN   A 1 151 ? 15.395  -0.790  32.469 1.000 18.314 0 151 ASN   A O   1 ? 
ATOM   1157 C CB  . ASN   A 1 151 ? 16.331  -0.622  29.259 1.000 20.964 0 151 ASN   A CB  1 ? 
ATOM   1158 C CG  . ASN   A 1 151 ? 16.077  -0.871  27.783 1.000 23.348 0 151 ASN   A CG  1 ? 
ATOM   1159 O OD1 . ASN   A 1 151 ? 16.430  -1.924  27.255 1.000 28.084 0 151 ASN   A OD1 1 ? 
ATOM   1160 N ND2 . ASN   A 1 151 ? 15.440  0.068   27.106 1.000 22.478 0 151 ASN   A ND2 1 ? 
ATOM   1161 N N   . ILE   A 1 152 ? 16.846  -2.392  31.863 1.000 23.787 0 152 ILE   A N   1 ? 
ATOM   1162 C CA  . ILE   A 1 152 ? 17.590  -2.418  33.114 1.000 27.313 0 152 ILE   A CA  1 ? 
ATOM   1163 C C   . ILE   A 1 152 ? 19.030  -1.972  32.837 1.000 32.307 0 152 ILE   A C   1 ? 
ATOM   1164 O O   . ILE   A 1 152 ? 19.679  -2.506  31.931 1.000 27.839 0 152 ILE   A O   1 ? 
ATOM   1165 C CB  . ILE   A 1 152 ? 17.527  -3.832  33.727 1.000 29.725 0 152 ILE   A CB  1 ? 
ATOM   1166 C CG1 . ILE   A 1 152 ? 16.080  -4.316  33.851 1.000 31.469 0 152 ILE   A CG1 1 ? 
ATOM   1167 C CG2 . ILE   A 1 152 ? 18.258  -3.877  35.063 1.000 28.841 0 152 ILE   A CG2 1 ? 
ATOM   1168 C CD1 . ILE   A 1 152 ? 15.937  -5.694  34.431 1.000 33.861 0 152 ILE   A CD1 1 ? 
ATOM   1169 N N   . ASP   A 1 153 ? 19.485  -0.954  33.590 1.000 41.892 0 153 ASP   A N   1 ? 
ATOM   1170 C CA  . ASP   A 1 153 ? 20.883  -0.531  33.639 1.000 51.035 0 153 ASP   A CA  1 ? 
ATOM   1171 C C   . ASP   A 1 153 ? 21.500  -0.965  34.973 1.000 49.947 0 153 ASP   A C   1 ? 
ATOM   1172 O O   . ASP   A 1 153 ? 21.511  -0.200  35.929 1.000 58.389 0 153 ASP   A O   1 ? 
ATOM   1173 C CB  . ASP   A 1 153 ? 21.053  0.992   33.552 1.000 54.964 0 153 ASP   A CB  1 ? 
ATOM   1174 C CG  . ASP   A 1 153 ? 20.268  1.708   32.463 1.000 66.327 0 153 ASP   A CG  1 ? 
ATOM   1175 O OD1 . ASP   A 1 153 ? 19.499  1.039   31.728 1.000 70.658 0 153 ASP   A OD1 1 ? 
ATOM   1176 O OD2 . ASP   A 1 153 ? 20.419  2.952   32.369 1.000 62.185 0 153 ASP   A OD2 1 ? 
ATOM   1177 N N   . TYR   A 1 154 ? 22.010  -2.195  35.035 1.000 55.497 0 154 TYR   A N   1 ? 
ATOM   1178 C CA  . TYR   A 1 154 ? 22.576  -2.761  36.255 1.000 61.084 0 154 TYR   A CA  1 ? 
ATOM   1179 C C   . TYR   A 1 154 ? 21.436  -3.082  37.232 1.000 56.663 0 154 TYR   A C   1 ? 
ATOM   1180 O O   . TYR   A 1 154 ? 20.855  -4.169  37.170 1.000 53.097 0 154 TYR   A O   1 ? 
ATOM   1181 C CB  . TYR   A 1 154 ? 23.705  -1.857  36.782 1.000 67.319 0 154 TYR   A CB  1 ? 
ATOM   1182 C CG  . TYR   A 1 154 ? 24.351  -2.286  38.098 1.000 78.219 0 154 TYR   A CG  1 ? 
ATOM   1183 C CD1 . TYR   A 1 154 ? 24.633  -3.625  38.373 1.000 78.351 0 154 TYR   A CD1 1 ? 
ATOM   1184 C CD2 . TYR   A 1 154 ? 24.710  -1.342  39.061 1.000 80.581 0 154 TYR   A CD2 1 ? 
ATOM   1185 C CE1 . TYR   A 1 154 ? 25.228  -4.010  39.565 1.000 76.949 0 154 TYR   A CE1 1 ? 
ATOM   1186 C CE2 . TYR   A 1 154 ? 25.312  -1.715  40.254 1.000 80.397 0 154 TYR   A CE2 1 ? 
ATOM   1187 C CZ  . TYR   A 1 154 ? 25.571  -3.051  40.503 1.000 77.726 0 154 TYR   A CZ  1 ? 
ATOM   1188 O OH  . TYR   A 1 154 ? 26.150  -3.414  41.681 1.000 83.298 0 154 TYR   A OH  1 ? 
ATOM   1189 N N   . ASP   A 1 155 ? 21.129  -2.141  38.135 1.000 48.113 0 155 ASP   A N   1 ? 
ATOM   1190 C CA  . ASP   A 1 155 ? 20.079  -2.306  39.132 1.000 46.876 0 155 ASP   A CA  1 ? 
ATOM   1191 C C   . ASP   A 1 155 ? 18.970  -1.280  38.910 1.000 38.842 0 155 ASP   A C   1 ? 
ATOM   1192 O O   . ASP   A 1 155 ? 17.973  -1.307  39.629 1.000 35.168 0 155 ASP   A O   1 ? 
ATOM   1193 C CB  . ASP   A 1 155 ? 20.639  -2.166  40.555 1.000 48.336 0 155 ASP   A CB  1 ? 
ATOM   1194 C CG  . ASP   A 1 155 ? 21.601  -0.999  40.743 1.000 55.535 0 155 ASP   A CG  1 ? 
ATOM   1195 O OD1 . ASP   A 1 155 ? 21.831  -0.236  39.768 1.000 52.512 0 155 ASP   A OD1 1 ? 
ATOM   1196 O OD2 . ASP   A 1 155 ? 22.146  -0.876  41.860 1.000 65.166 0 155 ASP   A OD2 1 ? 
ATOM   1197 N N   . CYS   A 1 156 ? 19.189  -0.370  37.941 1.000 36.147 0 156 CYS   A N   1 ? 
ATOM   1198 C CA  . CYS   A 1 156 ? 18.325  0.767   37.662 1.000 33.402 0 156 CYS   A CA  1 ? 
ATOM   1199 C C   . CYS   A 1 156 ? 17.387  0.417   36.514 1.000 27.835 0 156 CYS   A C   1 ? 
ATOM   1200 O O   . CYS   A 1 156 ? 17.850  0.091   35.426 1.000 28.543 0 156 CYS   A O   1 ? 
ATOM   1201 C CB  . CYS   A 1 156 ? 19.158  1.983   37.283 1.000 34.333 0 156 CYS   A CB  1 ? 
ATOM   1202 S SG  . CYS   A 1 156 ? 18.197  3.421   36.740 1.000 37.907 0 156 CYS   A SG  1 ? 
ATOM   1203 N N   . VAL   A 1 157 ? 16.078  0.461   36.773 1.000 22.966 0 157 VAL   A N   1 ? 
ATOM   1204 C CA  . VAL   A 1 157 ? 15.081  0.266   35.730 1.000 19.710 0 157 VAL   A CA  1 ? 
ATOM   1205 C C   . VAL   A 1 157 ? 14.777  1.609   35.080 1.000 18.914 0 157 VAL   A C   1 ? 
ATOM   1206 O O   . VAL   A 1 157 ? 14.339  2.549   35.745 1.000 20.375 0 157 VAL   A O   1 ? 
ATOM   1207 C CB  . VAL   A 1 157 ? 13.782  -0.352  36.275 1.000 18.713 0 157 VAL   A CB  1 ? 
ATOM   1208 C CG1 . VAL   A 1 157 ? 12.764  -0.561  35.154 1.000 17.589 0 157 VAL   A CG1 1 ? 
ATOM   1209 C CG2 . VAL   A 1 157 ? 14.040  -1.639  37.030 1.000 17.999 0 157 VAL   A CG2 1 ? 
ATOM   1210 N N   . SER   A 1 158 ? 15.027  1.682   33.775 1.000 17.364 0 158 SER   A N   1 ? 
ATOM   1211 C CA  . SER   A 1 158 ? 14.616  2.803   32.958 1.000 17.465 0 158 SER   A CA  1 ? 
ATOM   1212 C C   . SER   A 1 158 ? 13.290  2.460   32.293 1.000 17.517 0 158 SER   A C   1 ? 
ATOM   1213 O O   . SER   A 1 158 ? 13.241  1.605   31.421 1.000 17.252 0 158 SER   A O   1 ? 
ATOM   1214 C CB  . SER   A 1 158 ? 15.669  3.113   31.928 1.000 19.440 0 158 SER   A CB  1 ? 
ATOM   1215 O OG  . SER   A 1 158 ? 16.875  3.489   32.578 1.000 22.719 0 158 SER   A OG  1 ? 
ATOM   1216 N N   . PHE   A 1 159 ? 12.227  3.146   32.704 1.000 17.631 0 159 PHE   A N   1 ? 
ATOM   1217 C CA  . PHE   A 1 159 ? 10.938  2.993   32.062 1.000 17.541 0 159 PHE   A CA  1 ? 
ATOM   1218 C C   . PHE   A 1 159 ? 10.871  3.932   30.871 1.000 17.349 0 159 PHE   A C   1 ? 
ATOM   1219 O O   . PHE   A 1 159 ? 11.113  5.124   31.031 1.000 18.402 0 159 PHE   A O   1 ? 
ATOM   1220 C CB  . PHE   A 1 159 ? 9.813   3.314   33.045 1.000 18.040 0 159 PHE   A CB  1 ? 
ATOM   1221 C CG  . PHE   A 1 159 ? 9.729   2.381   34.221 1.000 16.965 0 159 PHE   A CG  1 ? 
ATOM   1222 C CD1 . PHE   A 1 159 ? 9.107   1.143   34.109 1.000 16.441 0 159 PHE   A CD1 1 ? 
ATOM   1223 C CD2 . PHE   A 1 159 ? 10.265  2.745   35.445 1.000 18.177 0 159 PHE   A CD2 1 ? 
ATOM   1224 C CE1 . PHE   A 1 159 ? 9.013   0.292   35.201 1.000 16.535 0 159 PHE   A CE1 1 ? 
ATOM   1225 C CE2 . PHE   A 1 159 ? 10.198  1.876   36.530 1.000 18.322 0 159 PHE   A CE2 1 ? 
ATOM   1226 C CZ  . PHE   A 1 159 ? 9.542   0.663   36.416 1.000 16.487 0 159 PHE   A CZ  1 ? 
ATOM   1227 N N   . CYS   A 1 160 ? 10.484  3.402   29.700 1.000 15.729 0 160 CYS   A N   1 ? 
ATOM   1228 C CA  . CYS   A 1 160 ? 10.477  4.211   28.495 1.000 15.475 0 160 CYS   A CA  1 ? 
ATOM   1229 C C   . CYS   A 1 160 ? 9.116   4.243   27.786 1.000 14.951 0 160 CYS   A C   1 ? 
ATOM   1230 O O   . CYS   A 1 160 ? 8.927   5.083   26.908 1.000 15.925 0 160 CYS   A O   1 ? 
ATOM   1231 C CB  . CYS   A 1 160 ? 11.552  3.737   27.524 1.000 17.327 0 160 CYS   A CB  1 ? 
ATOM   1232 S SG  . CYS   A 1 160 ? 11.433  1.989   27.057 1.000 19.103 0 160 CYS   A SG  1 ? 
ATOM   1233 N N   . TYR   A 1 161 ? 8.178   3.369   28.167 1.000 12.271 0 161 TYR   A N   1 ? 
ATOM   1234 C CA  . TYR   A 1 161 ? 6.974   3.163   27.396 1.000 12.444 0 161 TYR   A CA  1 ? 
ATOM   1235 C C   . TYR   A 1 161 ? 5.827   2.781   28.325 1.000 12.698 0 161 TYR   A C   1 ? 
ATOM   1236 O O   . TYR   A 1 161 ? 6.000   2.003   29.272 1.000 15.098 0 161 TYR   A O   1 ? 
ATOM   1237 C CB  . TYR   A 1 161 ? 7.125   2.067   26.329 1.000 12.044 0 161 TYR   A CB  1 ? 
ATOM   1238 C CG  . TYR   A 1 161 ? 5.887   1.765   25.492 1.000 11.707 0 161 TYR   A CG  1 ? 
ATOM   1239 C CD1 . TYR   A 1 161 ? 5.609   2.484   24.338 1.000 12.660 0 161 TYR   A CD1 1 ? 
ATOM   1240 C CD2 . TYR   A 1 161 ? 4.974   0.787   25.868 1.000 11.432 0 161 TYR   A CD2 1 ? 
ATOM   1241 C CE1 . TYR   A 1 161 ? 4.470   2.246   23.583 1.000 12.576 0 161 TYR   A CE1 1 ? 
ATOM   1242 C CE2 . TYR   A 1 161 ? 3.863   0.496   25.090 1.000 11.813 0 161 TYR   A CE2 1 ? 
ATOM   1243 C CZ  . TYR   A 1 161 ? 3.612   1.225   23.945 1.000 12.936 0 161 TYR   A CZ  1 ? 
ATOM   1244 O OH  . TYR   A 1 161 ? 2.531   0.965   23.159 1.000 14.827 0 161 TYR   A OH  1 ? 
ATOM   1245 N N   . MET   A 1 162 ? 4.658   3.342   28.034 1.000 12.390 0 162 MET   A N   1 ? 
ATOM   1246 C CA  . MET   A 1 162 ? 3.414   2.892   28.633 1.000 13.191 0 162 MET   A CA  1 ? 
ATOM   1247 C C   . MET   A 1 162 ? 2.377   2.733   27.520 1.000 11.885 0 162 MET   A C   1 ? 
ATOM   1248 O O   . MET   A 1 162 ? 2.212   3.615   26.683 1.000 9.817  0 162 MET   A O   1 ? 
ATOM   1249 C CB  . MET   A 1 162 ? 2.907   3.870   29.693 1.000 14.899 0 162 MET   A CB  1 ? 
ATOM   1250 C CG  . MET   A 1 162 ? 1.575   3.406   30.329 1.000 17.305 0 162 MET   A CG  1 ? 
ATOM   1251 S SD  . MET   A 1 162 ? 0.998   4.456   31.704 1.000 20.533 0 162 MET   A SD  1 ? 
ATOM   1252 C CE  . MET   A 1 162 ? 1.570   3.424   33.061 1.000 23.052 0 162 MET   A CE  1 ? 
ATOM   1253 N N   . HIS   A 1 163 ? 1.658   1.605   27.536 1.000 11.402 0 163 HIS   A N   1 ? 
ATOM   1254 C CA  . HIS   A 1 163 ? 0.780   1.252   26.422 1.000 11.555 0 163 HIS   A CA  1 ? 
ATOM   1255 C C   . HIS   A 1 163 ? -0.594  1.937   26.494 1.000 12.176 0 163 HIS   A C   1 ? 
ATOM   1256 O O   . HIS   A 1 163 ? -1.278  1.852   27.518 1.000 12.197 0 163 HIS   A O   1 ? 
ATOM   1257 C CB  . HIS   A 1 163 ? 0.562   -0.266  26.416 1.000 10.717 0 163 HIS   A CB  1 ? 
ATOM   1258 C CG  . HIS   A 1 163 ? -0.300  -0.672  25.297 1.000 11.084 0 163 HIS   A CG  1 ? 
ATOM   1259 N ND1 . HIS   A 1 163 ? 0.028   -0.274  24.015 1.000 11.260 0 163 HIS   A ND1 1 ? 
ATOM   1260 C CD2 . HIS   A 1 163 ? -1.453  -1.339  25.218 1.000 10.010 0 163 HIS   A CD2 1 ? 
ATOM   1261 C CE1 . HIS   A 1 163 ? -0.909  -0.696  23.193 1.000 10.257 0 163 HIS   A CE1 1 ? 
ATOM   1262 N NE2 . HIS   A 1 163 ? -1.804  -1.356  23.902 1.000 9.827  0 163 HIS   A NE2 1 ? 
ATOM   1263 N N   . HIS   A 1 164 ? -1.033  2.527   25.373 1.000 13.095 0 164 HIS   A N   1 ? 
ATOM   1264 C CA  . HIS   A 1 164 ? -2.323  3.193   25.308 1.000 13.461 0 164 HIS   A CA  1 ? 
ATOM   1265 C C   . HIS   A 1 164 ? -3.234  2.679   24.195 1.000 15.101 0 164 HIS   A C   1 ? 
ATOM   1266 O O   . HIS   A 1 164 ? -4.447  2.706   24.401 1.000 15.823 0 164 HIS   A O   1 ? 
ATOM   1267 C CB  . HIS   A 1 164 ? -2.231  4.704   25.077 1.000 13.353 0 164 HIS   A CB  1 ? 
ATOM   1268 C CG  . HIS   A 1 164 ? -1.588  5.433   26.189 1.000 13.223 0 164 HIS   A CG  1 ? 
ATOM   1269 N ND1 . HIS   A 1 164 ? -2.216  6.451   26.857 1.000 12.919 0 164 HIS   A ND1 1 ? 
ATOM   1270 C CD2 . HIS   A 1 164 ? -0.380  5.310   26.742 1.000 13.373 0 164 HIS   A CD2 1 ? 
ATOM   1271 C CE1 . HIS   A 1 164 ? -1.419  6.890   27.819 1.000 13.707 0 164 HIS   A CE1 1 ? 
ATOM   1272 N NE2 . HIS   A 1 164 ? -0.292  6.224   27.768 1.000 13.526 0 164 HIS   A NE2 1 ? 
ATOM   1273 N N   . MET   A 1 165 ? -2.722  2.316   23.012 1.000 16.169 0 165 MET   A N   1 ? 
ATOM   1274 C CA  . MET   A 1 165 ? -3.662  2.028   21.934 1.000 18.413 0 165 MET   A CA  1 ? 
ATOM   1275 C C   . MET   A 1 165 ? -3.077  1.159   20.832 1.000 17.336 0 165 MET   A C   1 ? 
ATOM   1276 O O   . MET   A 1 165 ? -1.873  0.998   20.716 1.000 16.107 0 165 MET   A O   1 ? 
ATOM   1277 C CB  . MET   A 1 165 ? -4.204  3.294   21.272 1.000 21.579 0 165 MET   A CB  1 ? 
ATOM   1278 C CG  . MET   A 1 165 ? -3.178  4.122   20.580 1.000 26.819 0 165 MET   A CG  1 ? 
ATOM   1279 S SD  . MET   A 1 165 ? -3.802  5.818   20.488 1.000 38.217 0 165 MET   A SD  1 ? 
ATOM   1280 C CE  . MET   A 1 165 ? -3.069  6.323   18.939 1.000 38.858 0 165 MET   A CE  1 ? 
ATOM   1281 N N   . GLU   A 1 166 ? -4.011  0.636   20.029 1.000 17.244 0 166 GLU   A N   1 ? 
ATOM   1282 C CA  . GLU   A 1 166 ? -3.733  -0.106  18.815 1.000 17.395 0 166 GLU   A CA  1 ? 
ATOM   1283 C C   . GLU   A 1 166 ? -4.109  0.714   17.573 1.000 16.675 0 166 GLU   A C   1 ? 
ATOM   1284 O O   . GLU   A 1 166 ? -5.141  1.387   17.552 1.000 14.797 0 166 GLU   A O   1 ? 
ATOM   1285 C CB  . GLU   A 1 166 ? -4.477  -1.433  18.864 1.000 18.901 0 166 GLU   A CB  1 ? 
ATOM   1286 C CG  . GLU   A 1 166 ? -4.292  -2.226  17.594 1.000 23.589 0 166 GLU   A CG  1 ? 
ATOM   1287 C CD  . GLU   A 1 166 ? -4.558  -3.718  17.638 1.000 27.004 0 166 GLU   A CD  1 ? 
ATOM   1288 O OE1 . GLU   A 1 166 ? -4.945  -4.224  16.564 1.000 28.884 0 166 GLU   A OE1 1 ? 
ATOM   1289 O OE2 . GLU   A 1 166 ? -4.311  -4.372  18.707 1.000 27.054 0 166 GLU   A OE2 1 ? 
ATOM   1290 N N   . LEU   A 1 167 ? -3.249  0.624   16.544 1.000 15.508 0 167 LEU   A N   1 ? 
ATOM   1291 C CA  . LEU   A 1 167 ? -3.430  1.299   15.264 1.000 16.174 0 167 LEU   A CA  1 ? 
ATOM   1292 C C   . LEU   A 1 167 ? -3.624  0.291   14.130 1.000 18.204 0 167 LEU   A C   1 ? 
ATOM   1293 O O   . LEU   A 1 167 ? -3.349  -0.901  14.304 1.000 16.089 0 167 LEU   A O   1 ? 
ATOM   1294 C CB  . LEU   A 1 167 ? -2.165  2.099   14.985 1.000 15.787 0 167 LEU   A CB  1 ? 
ATOM   1295 C CG  . LEU   A 1 167 ? -1.915  3.255   15.938 1.000 15.750 0 167 LEU   A CG  1 ? 
ATOM   1296 C CD1 . LEU   A 1 167 ? -0.498  3.750   15.782 1.000 15.874 0 167 LEU   A CD1 1 ? 
ATOM   1297 C CD2 . LEU   A 1 167 ? -2.917  4.359   15.692 1.000 16.182 0 167 LEU   A CD2 1 ? 
ATOM   1298 N N   . PRO   A 1 168 ? -4.017  0.744   12.913 1.000 18.629 0 168 PRO   A N   1 ? 
ATOM   1299 C CA  . PRO   A 1 168 ? -4.249  -0.179  11.797 1.000 21.200 0 168 PRO   A CA  1 ? 
ATOM   1300 C C   . PRO   A 1 168 ? -3.052  -1.079  11.514 1.000 24.378 0 168 PRO   A C   1 ? 
ATOM   1301 O O   . PRO   A 1 168 ? -1.906  -0.670  11.713 1.000 30.083 0 168 PRO   A O   1 ? 
ATOM   1302 C CB  . PRO   A 1 168 ? -4.579  0.755   10.613 1.000 20.164 0 168 PRO   A CB  1 ? 
ATOM   1303 C CG  . PRO   A 1 168 ? -5.210  1.956   11.320 1.000 20.309 0 168 PRO   A CG  1 ? 
ATOM   1304 C CD  . PRO   A 1 168 ? -4.325  2.135   12.549 1.000 17.803 0 168 PRO   A CD  1 ? 
ATOM   1305 N N   . THR   A 1 169 ? -3.378  -2.310  11.093 1.000 27.032 0 169 THR   A N   1 ? 
ATOM   1306 C CA  . THR   A 1 169 ? -2.464  -3.406  10.811 1.000 29.087 0 169 THR   A CA  1 ? 
ATOM   1307 C C   . THR   A 1 169 ? -1.944  -4.027  12.107 1.000 29.080 0 169 THR   A C   1 ? 
ATOM   1308 O O   . THR   A 1 169 ? -1.014  -4.824  12.064 1.000 30.858 0 169 THR   A O   1 ? 
ATOM   1309 C CB  . THR   A 1 169 ? -1.294  -3.027  9.887  1.000 31.172 0 169 THR   A CB  1 ? 
ATOM   1310 O OG1 . THR   A 1 169 ? -0.307  -2.312  10.638 1.000 32.225 0 169 THR   A OG1 1 ? 
ATOM   1311 C CG2 . THR   A 1 169 ? -1.706  -2.237  8.660  1.000 31.231 0 169 THR   A CG2 1 ? 
ATOM   1312 N N   . GLY   A 1 170 ? -2.542  -3.693  13.257 1.000 26.451 0 170 GLY   A N   1 ? 
ATOM   1313 C CA  . GLY   A 1 170 ? -2.231  -4.412  14.479 1.000 24.880 0 170 GLY   A CA  1 ? 
ATOM   1314 C C   . GLY   A 1 170 ? -0.888  -4.018  15.109 1.000 22.474 0 170 GLY   A C   1 ? 
ATOM   1315 O O   . GLY   A 1 170 ? -0.226  -4.873  15.687 1.000 23.775 0 170 GLY   A O   1 ? 
ATOM   1316 N N   . VAL   A 1 171 ? -0.511  -2.738  15.018 1.000 18.129 0 171 VAL   A N   1 ? 
ATOM   1317 C CA  . VAL   A 1 171 ? 0.644   -2.201  15.733 1.000 17.486 0 171 VAL   A CA  1 ? 
ATOM   1318 C C   . VAL   A 1 171 ? 0.139   -1.224  16.790 1.000 15.916 0 171 VAL   A C   1 ? 
ATOM   1319 O O   . VAL   A 1 171 ? -1.039  -0.889  16.841 1.000 15.780 0 171 VAL   A O   1 ? 
ATOM   1320 C CB  . VAL   A 1 171 ? 1.673   -1.512  14.808 1.000 16.600 0 171 VAL   A CB  1 ? 
ATOM   1321 C CG1 . VAL   A 1 171 ? 2.215   -2.475  13.756 1.000 17.963 0 171 VAL   A CG1 1 ? 
ATOM   1322 C CG2 . VAL   A 1 171 ? 1.085   -0.279  14.146 1.000 16.227 0 171 VAL   A CG2 1 ? 
ATOM   1323 N N   . HIS   A 1 172 ? 1.067   -0.759  17.623 1.000 14.699 0 172 HIS   A N   1 ? 
ATOM   1324 C CA  . HIS   A 1 172 ? 0.702   -0.232  18.908 1.000 14.230 0 172 HIS   A CA  1 ? 
ATOM   1325 C C   . HIS   A 1 172 ? 1.382   1.106   19.135 1.000 13.782 0 172 HIS   A C   1 ? 
ATOM   1326 O O   . HIS   A 1 172 ? 2.458   1.386   18.594 1.000 13.818 0 172 HIS   A O   1 ? 
ATOM   1327 C CB  . HIS   A 1 172 ? 1.048   -1.282  19.950 1.000 14.807 0 172 HIS   A CB  1 ? 
ATOM   1328 C CG  . HIS   A 1 172 ? 0.243   -2.511  19.789 1.000 16.260 0 172 HIS   A CG  1 ? 
ATOM   1329 N ND1 . HIS   A 1 172 ? 0.825   -3.667  19.331 1.000 17.532 0 172 HIS   A ND1 1 ? 
ATOM   1330 C CD2 . HIS   A 1 172 ? -1.065  -2.787  19.975 1.000 17.285 0 172 HIS   A CD2 1 ? 
ATOM   1331 C CE1 . HIS   A 1 172 ? -0.090  -4.627  19.303 1.000 18.543 0 172 HIS   A CE1 1 ? 
ATOM   1332 N NE2 . HIS   A 1 172 ? -1.249  -4.112  19.669 1.000 17.806 0 172 HIS   A NE2 1 ? 
ATOM   1333 N N   . ALA   A 1 173 ? 0.742   1.908   19.983 1.000 12.323 0 173 ALA   A N   1 ? 
ATOM   1334 C CA  . ALA   A 1 173 ? 1.219   3.239   20.277 1.000 12.349 0 173 ALA   A CA  1 ? 
ATOM   1335 C C   . ALA   A 1 173 ? 0.977   3.552   21.742 1.000 11.772 0 173 ALA   A C   1 ? 
ATOM   1336 O O   . ALA   A 1 173 ? 0.061   3.029   22.369 1.000 12.498 0 173 ALA   A O   1 ? 
ATOM   1337 C CB  . ALA   A 1 173 ? 0.549   4.234   19.344 1.000 12.890 0 173 ALA   A CB  1 ? 
ATOM   1338 N N   . GLY   A 1 174 ? 1.824   4.428   22.272 1.000 12.349 0 174 GLY   A N   1 ? 
ATOM   1339 C CA  . GLY   A 1 174 ? 1.807   4.785   23.677 1.000 13.116 0 174 GLY   A CA  1 ? 
ATOM   1340 C C   . GLY   A 1 174 ? 2.751   5.954   23.954 1.000 13.892 0 174 GLY   A C   1 ? 
ATOM   1341 O O   . GLY   A 1 174 ? 3.204   6.611   23.027 1.000 14.616 0 174 GLY   A O   1 ? 
ATOM   1342 N N   . THR   A 1 175 ? 3.047   6.190   25.235 1.000 14.261 0 175 THR   A N   1 ? 
ATOM   1343 C CA  . THR   A 1 175 ? 3.722   7.398   25.694 1.000 14.486 0 175 THR   A CA  1 ? 
ATOM   1344 C C   . THR   A 1 175 ? 4.981   7.005   26.451 1.000 15.230 0 175 THR   A C   1 ? 
ATOM   1345 O O   . THR   A 1 175 ? 5.116   5.848   26.841 1.000 14.743 0 175 THR   A O   1 ? 
ATOM   1346 C CB  . THR   A 1 175 ? 2.801   8.200   26.637 1.000 13.964 0 175 THR   A CB  1 ? 
ATOM   1347 O OG1 . THR   A 1 175 ? 2.501   7.468   27.847 1.000 13.804 0 175 THR   A OG1 1 ? 
ATOM   1348 C CG2 . THR   A 1 175 ? 1.495   8.564   25.964 1.000 13.707 0 175 THR   A CG2 1 ? 
ATOM   1349 N N   . ASP   A 1 176 ? 5.853   7.988   26.699 1.000 16.143 0 176 ASP   A N   1 ? 
ATOM   1350 C CA  . ASP   A 1 176 ? 6.831   7.906   27.771 1.000 15.947 0 176 ASP   A CA  1 ? 
ATOM   1351 C C   . ASP   A 1 176 ? 6.095   8.069   29.093 1.000 15.130 0 176 ASP   A C   1 ? 
ATOM   1352 O O   . ASP   A 1 176 ? 4.868   8.173   29.129 1.000 13.114 0 176 ASP   A O   1 ? 
ATOM   1353 C CB  . ASP   A 1 176 ? 7.961   8.917   27.567 1.000 17.438 0 176 ASP   A CB  1 ? 
ATOM   1354 C CG  . ASP   A 1 176 ? 7.533   10.377  27.593 1.000 17.064 0 176 ASP   A CG  1 ? 
ATOM   1355 O OD1 . ASP   A 1 176 ? 6.464   10.686  28.198 1.000 15.709 0 176 ASP   A OD1 1 ? 
ATOM   1356 O OD2 . ASP   A 1 176 ? 8.230   11.174  26.926 1.000 17.712 0 176 ASP   A OD2 1 ? 
ATOM   1357 N N   . LEU   A 1 177 ? 6.845   8.005   30.194 1.000 15.575 0 177 LEU   A N   1 ? 
ATOM   1358 C CA  . LEU   A 1 177 ? 6.224   8.012   31.513 1.000 17.188 0 177 LEU   A CA  1 ? 
ATOM   1359 C C   . LEU   A 1 177 ? 5.965   9.452   31.981 1.000 18.327 0 177 LEU   A C   1 ? 
ATOM   1360 O O   . LEU   A 1 177 ? 5.435   9.630   33.056 1.000 18.824 0 177 LEU   A O   1 ? 
ATOM   1361 C CB  . LEU   A 1 177 ? 7.079   7.237   32.530 1.000 16.849 0 177 LEU   A CB  1 ? 
ATOM   1362 C CG  . LEU   A 1 177 ? 6.721   5.760   32.722 1.000 17.479 0 177 LEU   A CG  1 ? 
ATOM   1363 C CD1 . LEU   A 1 177 ? 5.339   5.612   33.319 1.000 17.239 0 177 LEU   A CD1 1 ? 
ATOM   1364 C CD2 . LEU   A 1 177 ? 6.793   4.977   31.413 1.000 18.234 0 177 LEU   A CD2 1 ? 
ATOM   1365 N N   . GLU   A 1 178 ? 6.253   10.466  31.156 1.000 19.508 0 178 GLU   A N   1 ? 
ATOM   1366 C CA  . GLU   A 1 178 ? 5.719   11.804  31.367 1.000 20.258 0 178 GLU   A CA  1 ? 
ATOM   1367 C C   . GLU   A 1 178 ? 4.454   12.014  30.540 1.000 18.502 0 178 GLU   A C   1 ? 
ATOM   1368 O O   . GLU   A 1 178 ? 3.935   13.119  30.497 1.000 21.429 0 178 GLU   A O   1 ? 
ATOM   1369 C CB  . GLU   A 1 178 ? 6.756   12.864  30.985 1.000 22.646 0 178 GLU   A CB  1 ? 
ATOM   1370 C CG  . GLU   A 1 178 ? 8.061   12.743  31.766 1.000 26.193 0 178 GLU   A CG  1 ? 
ATOM   1371 C CD  . GLU   A 1 178 ? 9.099   13.818  31.446 1.000 33.102 0 178 GLU   A CD  1 ? 
ATOM   1372 O OE1 . GLU   A 1 178 ? 9.351   14.068  30.240 1.000 33.108 0 178 GLU   A OE1 1 ? 
ATOM   1373 O OE2 . GLU   A 1 178 ? 9.657   14.408  32.399 1.000 37.426 0 178 GLU   A OE2 1 ? 
ATOM   1374 N N   . GLY   A 1 179 ? 3.978   10.977  29.843 1.000 16.854 0 179 GLY   A N   1 ? 
ATOM   1375 C CA  . GLY   A 1 179 ? 2.671   11.018  29.196 1.000 15.300 0 179 GLY   A CA  1 ? 
ATOM   1376 C C   . GLY   A 1 179 ? 2.673   11.691  27.822 1.000 14.587 0 179 GLY   A C   1 ? 
ATOM   1377 O O   . GLY   A 1 179 ? 1.609   11.929  27.240 1.000 14.526 0 179 GLY   A O   1 ? 
ATOM   1378 N N   . ASN   A 1 180 ? 3.857   11.915  27.246 1.000 15.222 0 180 ASN   A N   1 ? 
ATOM   1379 C CA  . ASN   A 1 180 ? 3.952   12.359  25.869 1.000 15.696 0 180 ASN   A CA  1 ? 
ATOM   1380 C C   . ASN   A 1 180 ? 4.040   11.144  24.944 1.000 16.169 0 180 ASN   A C   1 ? 
ATOM   1381 O O   . ASN   A 1 180 ? 4.889   10.279  25.131 1.000 14.970 0 180 ASN   A O   1 ? 
ATOM   1382 C CB  . ASN   A 1 180 ? 5.147   13.270  25.629 1.000 16.997 0 180 ASN   A CB  1 ? 
ATOM   1383 C CG  . ASN   A 1 180 ? 5.046   14.568  26.404 1.000 17.962 0 180 ASN   A CG  1 ? 
ATOM   1384 O OD1 . ASN   A 1 180 ? 5.891   14.888  27.242 1.000 20.303 0 180 ASN   A OD1 1 ? 
ATOM   1385 N ND2 . ASN   A 1 180 ? 4.009   15.320  26.137 1.000 19.265 0 180 ASN   A ND2 1 ? 
ATOM   1386 N N   . PHE   A 1 181 ? 3.175   11.152  23.924 1.000 15.487 0 181 PHE   A N   1 ? 
ATOM   1387 C CA  . PHE   A 1 181 ? 3.139   10.142  22.889 1.000 16.014 0 181 PHE   A CA  1 ? 
ATOM   1388 C C   . PHE   A 1 181 ? 4.444   10.107  22.105 1.000 15.355 0 181 PHE   A C   1 ? 
ATOM   1389 O O   . PHE   A 1 181 ? 5.084   11.118  21.913 1.000 13.971 0 181 PHE   A O   1 ? 
ATOM   1390 C CB  . PHE   A 1 181 ? 1.953   10.380  21.956 1.000 16.262 0 181 PHE   A CB  1 ? 
ATOM   1391 C CG  . PHE   A 1 181 ? 0.768   9.529   22.309 1.000 17.680 0 181 PHE   A CG  1 ? 
ATOM   1392 C CD1 . PHE   A 1 181 ? 0.689   8.208   21.872 1.000 17.576 0 181 PHE   A CD1 1 ? 
ATOM   1393 C CD2 . PHE   A 1 181 ? -0.235  10.028  23.130 1.000 19.494 0 181 PHE   A CD2 1 ? 
ATOM   1394 C CE1 . PHE   A 1 181 ? -0.393  7.419   22.230 1.000 18.162 0 181 PHE   A CE1 1 ? 
ATOM   1395 C CE2 . PHE   A 1 181 ? -1.318  9.236   23.482 1.000 19.334 0 181 PHE   A CE2 1 ? 
ATOM   1396 C CZ  . PHE   A 1 181 ? -1.404  7.942   23.012 1.000 18.174 0 181 PHE   A CZ  1 ? 
ATOM   1397 N N   . TYR   A 1 182 ? 4.850   8.892   21.735 1.000 15.366 0 182 TYR   A N   1 ? 
ATOM   1398 C CA  . TYR   A 1 182 ? 5.800   8.677   20.664 1.000 15.497 0 182 TYR   A CA  1 ? 
ATOM   1399 C C   . TYR   A 1 182 ? 5.018   8.779   19.359 1.000 15.356 0 182 TYR   A C   1 ? 
ATOM   1400 O O   . TYR   A 1 182 ? 4.019   8.083   19.188 1.000 14.568 0 182 TYR   A O   1 ? 
ATOM   1401 C CB  . TYR   A 1 182 ? 6.445   7.303   20.870 1.000 15.043 0 182 TYR   A CB  1 ? 
ATOM   1402 C CG  . TYR   A 1 182 ? 7.404   7.166   22.051 1.000 15.575 0 182 TYR   A CG  1 ? 
ATOM   1403 C CD1 . TYR   A 1 182 ? 8.730   7.618   21.993 1.000 14.992 0 182 TYR   A CD1 1 ? 
ATOM   1404 C CD2 . TYR   A 1 182 ? 6.993   6.541   23.219 1.000 14.686 0 182 TYR   A CD2 1 ? 
ATOM   1405 C CE1 . TYR   A 1 182 ? 9.598   7.455   23.065 1.000 14.324 0 182 TYR   A CE1 1 ? 
ATOM   1406 C CE2 . TYR   A 1 182 ? 7.849   6.386   24.302 1.000 15.356 0 182 TYR   A CE2 1 ? 
ATOM   1407 C CZ  . TYR   A 1 182 ? 9.156   6.853   24.229 1.000 14.908 0 182 TYR   A CZ  1 ? 
ATOM   1408 O OH  . TYR   A 1 182 ? 9.978   6.654   25.308 1.000 13.978 0 182 TYR   A OH  1 ? 
ATOM   1409 N N   . GLY   A 1 183 ? 5.470   9.656   18.456 1.000 16.378 0 183 GLY   A N   1 ? 
ATOM   1410 C CA  . GLY   A 1 183 ? 4.772   9.908   17.210 1.000 17.717 0 183 GLY   A CA  1 ? 
ATOM   1411 C C   . GLY   A 1 183 ? 3.610   10.884  17.369 1.000 18.856 0 183 GLY   A C   1 ? 
ATOM   1412 O O   . GLY   A 1 183 ? 3.376   11.416  18.443 1.000 21.055 0 183 GLY   A O   1 ? 
ATOM   1413 N N   . PRO   A 1 184 ? 2.865   11.168  16.286 1.000 20.570 0 184 PRO   A N   1 ? 
ATOM   1414 C CA  . PRO   A 1 184 ? 1.782   12.165  16.308 1.000 21.578 0 184 PRO   A CA  1 ? 
ATOM   1415 C C   . PRO   A 1 184 ? 0.401   11.602  16.638 1.000 23.666 0 184 PRO   A C   1 ? 
ATOM   1416 O O   . PRO   A 1 184 ? -0.610  12.035  16.084 1.000 32.973 0 184 PRO   A O   1 ? 
ATOM   1417 C CB  . PRO   A 1 184 ? 1.828   12.673  14.853 1.000 21.001 0 184 PRO   A CB  1 ? 
ATOM   1418 C CG  . PRO   A 1 184 ? 2.141   11.397  14.056 1.000 21.221 0 184 PRO   A CG  1 ? 
ATOM   1419 C CD  . PRO   A 1 184 ? 3.083   10.597  14.946 1.000 19.994 0 184 PRO   A CD  1 ? 
ATOM   1420 N N   . PHE   A 1 185 ? 0.336   10.650  17.561 1.000 21.194 0 185 PHE   A N   1 ? 
ATOM   1421 C CA  . PHE   A 1 185 ? -0.927  10.003  17.875 1.000 21.054 0 185 PHE   A CA  1 ? 
ATOM   1422 C C   . PHE   A 1 185 ? -1.588  10.697  19.062 1.000 21.750 0 185 PHE   A C   1 ? 
ATOM   1423 O O   . PHE   A 1 185 ? -0.916  11.321  19.873 1.000 20.345 0 185 PHE   A O   1 ? 
ATOM   1424 C CB  . PHE   A 1 185 ? -0.691  8.510   18.120 1.000 19.666 0 185 PHE   A CB  1 ? 
ATOM   1425 C CG  . PHE   A 1 185 ? 0.126   7.879   17.024 1.000 19.381 0 185 PHE   A CG  1 ? 
ATOM   1426 C CD1 . PHE   A 1 185 ? -0.369  7.802   15.728 1.000 18.841 0 185 PHE   A CD1 1 ? 
ATOM   1427 C CD2 . PHE   A 1 185 ? 1.419   7.435   17.261 1.000 18.027 0 185 PHE   A CD2 1 ? 
ATOM   1428 C CE1 . PHE   A 1 185 ? 0.404   7.277   14.703 1.000 18.697 0 185 PHE   A CE1 1 ? 
ATOM   1429 C CE2 . PHE   A 1 185 ? 2.178   6.877   16.242 1.000 17.378 0 185 PHE   A CE2 1 ? 
ATOM   1430 C CZ  . PHE   A 1 185 ? 1.679   6.805   14.963 1.000 18.678 0 185 PHE   A CZ  1 ? 
ATOM   1431 N N   . VAL   A 1 186 ? -2.917  10.541  19.179 1.000 23.552 0 186 VAL   A N   1 ? 
ATOM   1432 C CA  . VAL   A 1 186 ? -3.674  11.128  20.284 1.000 21.724 0 186 VAL   A CA  1 ? 
ATOM   1433 C C   . VAL   A 1 186 ? -4.517  10.046  20.945 1.000 20.473 0 186 VAL   A C   1 ? 
ATOM   1434 O O   . VAL   A 1 186 ? -4.938  9.081   20.288 1.000 17.066 0 186 VAL   A O   1 ? 
ATOM   1435 C CB  . VAL   A 1 186 ? -4.581  12.286  19.825 1.000 23.473 0 186 VAL   A CB  1 ? 
ATOM   1436 C CG1 . VAL   A 1 186 ? -3.774  13.559  19.578 1.000 22.862 0 186 VAL   A CG1 1 ? 
ATOM   1437 C CG2 . VAL   A 1 186 ? -5.421  11.896  18.600 1.000 23.664 0 186 VAL   A CG2 1 ? 
ATOM   1438 N N   . ASP   A 1 187 ? -4.761  10.217  22.254 1.000 18.962 0 187 ASP   A N   1 ? 
ATOM   1439 C CA  . ASP   A 1 187 ? -5.509  9.209   22.979 1.000 19.902 0 187 ASP   A CA  1 ? 
ATOM   1440 C C   . ASP   A 1 187 ? -7.004  9.483   22.839 1.000 21.170 0 187 ASP   A C   1 ? 
ATOM   1441 O O   . ASP   A 1 187 ? -7.653  9.962   23.767 1.000 20.566 0 187 ASP   A O   1 ? 
ATOM   1442 C CB  . ASP   A 1 187 ? -5.026  9.058   24.421 1.000 20.193 0 187 ASP   A CB  1 ? 
ATOM   1443 C CG  . ASP   A 1 187 ? -5.022  10.332  25.248 1.000 20.930 0 187 ASP   A CG  1 ? 
ATOM   1444 O OD1 . ASP   A 1 187 ? -5.140  11.439  24.676 1.000 19.037 0 187 ASP   A OD1 1 ? 
ATOM   1445 O OD2 . ASP   A 1 187 ? -4.953  10.182  26.470 1.000 21.990 0 187 ASP   A OD2 1 ? 
ATOM   1446 N N   . ARG   A 1 188 ? -7.549  9.155   21.663 1.000 23.357 0 188 ARG   A N   1 ? 
ATOM   1447 C CA  . ARG   A 1 188 ? -8.990  9.190   21.465 1.000 27.181 0 188 ARG   A CA  1 ? 
ATOM   1448 C C   . ARG   A 1 188 ? -9.392  8.193   20.380 1.000 24.428 0 188 ARG   A C   1 ? 
ATOM   1449 O O   . ARG   A 1 188 ? -8.553  7.717   19.635 1.000 20.770 0 188 ARG   A O   1 ? 
ATOM   1450 C CB  . ARG   A 1 188 ? -9.447  10.616  21.163 1.000 30.178 0 188 ARG   A CB  1 ? 
ATOM   1451 C CG  . ARG   A 1 188 ? -8.869  11.207  19.894 1.000 34.715 0 188 ARG   A CG  1 ? 
ATOM   1452 C CD  . ARG   A 1 188 ? -9.294  12.657  19.755 1.000 42.190 0 188 ARG   A CD  1 ? 
ATOM   1453 N NE  . ARG   A 1 188 ? -10.592 12.822  19.120 1.000 47.861 0 188 ARG   A NE  1 ? 
ATOM   1454 C CZ  . ARG   A 1 188 ? -10.822 13.584  18.048 1.000 51.875 0 188 ARG   A CZ  1 ? 
ATOM   1455 N NH1 . ARG   A 1 188 ? -9.864  14.340  17.541 1.000 53.780 0 188 ARG   A NH1 1 ? 
ATOM   1456 N NH2 . ARG   A 1 188 ? -12.017 13.601  17.487 1.000 49.713 0 188 ARG   A NH2 1 ? 
ATOM   1457 N N   . GLN   A 1 189 ? -10.681 7.867   20.341 1.000 25.154 0 189 GLN   A N   1 ? 
ATOM   1458 C CA  . GLN   A 1 189 ? -11.205 6.845   19.456 1.000 29.216 0 189 GLN   A CA  1 ? 
ATOM   1459 C C   . GLN   A 1 189 ? -11.555 7.530   18.138 1.000 32.196 0 189 GLN   A C   1 ? 
ATOM   1460 O O   . GLN   A 1 189 ? -12.661 8.015   17.939 1.000 35.052 0 189 GLN   A O   1 ? 
ATOM   1461 C CB  . GLN   A 1 189 ? -12.376 6.119   20.122 1.000 30.171 0 189 GLN   A CB  1 ? 
ATOM   1462 C CG  . GLN   A 1 189 ? -13.054 5.058   19.249 1.000 32.786 0 189 GLN   A CG  1 ? 
ATOM   1463 C CD  . GLN   A 1 189 ? -14.116 4.253   19.979 1.000 33.515 0 189 GLN   A CD  1 ? 
ATOM   1464 O OE1 . GLN   A 1 189 ? -14.719 3.315   19.443 1.000 31.641 0 189 GLN   A OE1 1 ? 
ATOM   1465 N NE2 . GLN   A 1 189 ? -14.307 4.568   21.248 1.000 31.891 0 189 GLN   A NE2 1 ? 
ATOM   1466 N N   . THR   A 1 190 ? -10.566 7.555   17.252 1.000 32.690 0 190 THR   A N   1 ? 
ATOM   1467 C CA  . THR   A 1 190 ? -10.563 8.408   16.083 1.000 35.077 0 190 THR   A CA  1 ? 
ATOM   1468 C C   . THR   A 1 190 ? -9.665  7.700   15.074 1.000 34.297 0 190 THR   A C   1 ? 
ATOM   1469 O O   . THR   A 1 190 ? -8.768  6.958   15.466 1.000 29.734 0 190 THR   A O   1 ? 
ATOM   1470 C CB  . THR   A 1 190 ? -10.136 9.843   16.454 1.000 34.361 0 190 THR   A CB  1 ? 
ATOM   1471 O OG1 . THR   A 1 190 ? -10.784 10.754  15.587 1.000 31.086 0 190 THR   A OG1 1 ? 
ATOM   1472 C CG2 . THR   A 1 190 ? -8.655  10.139  16.336 1.000 37.084 0 190 THR   A CG2 1 ? 
ATOM   1473 N N   . ALA   A 1 191 ? -9.950  7.914   13.791 1.000 31.806 0 191 ALA   A N   1 ? 
ATOM   1474 C CA  . ALA   A 1 191 ? -9.167  7.339   12.721 1.000 33.563 0 191 ALA   A CA  1 ? 
ATOM   1475 C C   . ALA   A 1 191 ? -7.774  7.956   12.765 1.000 31.910 0 191 ALA   A C   1 ? 
ATOM   1476 O O   . ALA   A 1 191 ? -7.625  9.168   12.579 1.000 32.429 0 191 ALA   A O   1 ? 
ATOM   1477 C CB  . ALA   A 1 191 ? -9.839  7.610   11.390 1.000 34.185 0 191 ALA   A CB  1 ? 
ATOM   1478 N N   . GLN   A 1 192 ? -6.771  7.115   13.027 1.000 25.018 0 192 GLN   A N   1 ? 
ATOM   1479 C CA  . GLN   A 1 192 ? -5.390  7.544   12.908 1.000 25.948 0 192 GLN   A CA  1 ? 
ATOM   1480 C C   . GLN   A 1 192 ? -4.613  6.407   12.273 1.000 24.728 0 192 GLN   A C   1 ? 
ATOM   1481 O O   . GLN   A 1 192 ? -4.967  5.245   12.443 1.000 26.791 0 192 GLN   A O   1 ? 
ATOM   1482 C CB  . GLN   A 1 192 ? -4.721  7.865   14.248 1.000 23.960 0 192 GLN   A CB  1 ? 
ATOM   1483 C CG  . GLN   A 1 192 ? -5.662  8.374   15.314 1.000 25.288 0 192 GLN   A CG  1 ? 
ATOM   1484 C CD  . GLN   A 1 192 ? -4.994  8.561   16.658 1.000 23.855 0 192 GLN   A CD  1 ? 
ATOM   1485 O OE1 . GLN   A 1 192 ? -3.976  9.230   16.800 1.000 21.597 0 192 GLN   A OE1 1 ? 
ATOM   1486 N NE2 . GLN   A 1 192 ? -5.609  8.012   17.680 1.000 23.974 0 192 GLN   A NE2 1 ? 
ATOM   1487 N N   . ALA   A 1 193 ? -3.551  6.778   11.574 1.000 24.218 0 193 ALA   A N   1 ? 
ATOM   1488 C CA  . ALA   A 1 193 ? -2.700  5.827   10.882 1.000 27.227 0 193 ALA   A CA  1 ? 
ATOM   1489 C C   . ALA   A 1 193 ? -1.248  6.272   11.033 1.000 23.882 0 193 ALA   A C   1 ? 
ATOM   1490 O O   . ALA   A 1 193 ? -0.957  7.463   10.975 1.000 21.555 0 193 ALA   A O   1 ? 
ATOM   1491 C CB  . ALA   A 1 193 ? -3.090  5.749   9.415  1.000 28.886 0 193 ALA   A CB  1 ? 
ATOM   1492 N N   . ALA   A 1 194 ? -0.376  5.282   11.239 1.000 22.839 0 194 ALA   A N   1 ? 
ATOM   1493 C CA  . ALA   A 1 194 ? 1.065   5.463   11.239 1.000 24.597 0 194 ALA   A CA  1 ? 
ATOM   1494 C C   . ALA   A 1 194 ? 1.564   5.665   9.810  1.000 23.332 0 194 ALA   A C   1 ? 
ATOM   1495 O O   . ALA   A 1 194 ? 0.951   5.195   8.858  1.000 25.384 0 194 ALA   A O   1 ? 
ATOM   1496 C CB  . ALA   A 1 194 ? 1.710   4.247   11.857 1.000 24.144 0 194 ALA   A CB  1 ? 
ATOM   1497 N N   . GLY   A 1 195 ? 2.697   6.344   9.669  1.000 21.692 0 195 GLY   A N   1 ? 
ATOM   1498 C CA  . GLY   A 1 195 ? 3.367   6.408   8.382  1.000 20.139 0 195 GLY   A CA  1 ? 
ATOM   1499 C C   . GLY   A 1 195 ? 4.023   5.073   8.016  1.000 19.173 0 195 GLY   A C   1 ? 
ATOM   1500 O O   . GLY   A 1 195 ? 4.166   4.160   8.846  1.000 17.858 0 195 GLY   A O   1 ? 
ATOM   1501 N N   . THR   A 1 196 ? 4.446   4.990   6.757  1.000 18.191 0 196 THR   A N   1 ? 
ATOM   1502 C CA  . THR   A 1 196 ? 5.221   3.867   6.259  1.000 18.896 0 196 THR   A CA  1 ? 
ATOM   1503 C C   . THR   A 1 196 ? 6.413   3.609   7.166  1.000 17.211 0 196 THR   A C   1 ? 
ATOM   1504 O O   . THR   A 1 196 ? 7.153   4.518   7.507  1.000 15.531 0 196 THR   A O   1 ? 
ATOM   1505 C CB  . THR   A 1 196 ? 5.666   4.096   4.812  1.000 19.362 0 196 THR   A CB  1 ? 
ATOM   1506 O OG1 . THR   A 1 196 ? 4.477   4.462   4.112  1.000 17.521 0 196 THR   A OG1 1 ? 
ATOM   1507 C CG2 . THR   A 1 196 ? 6.307   2.862   4.213  1.000 19.747 0 196 THR   A CG2 1 ? 
ATOM   1508 N N   . ASP   A 1 197 ? 6.554   2.349   7.589  1.000 18.765 0 197 ASP   A N   1 ? 
ATOM   1509 C CA  . ASP   A 1 197 ? 7.683   1.968   8.414  1.000 19.284 0 197 ASP   A CA  1 ? 
ATOM   1510 C C   . ASP   A 1 197 ? 8.881   1.697   7.508  1.000 19.902 0 197 ASP   A C   1 ? 
ATOM   1511 O O   . ASP   A 1 197 ? 8.713   1.325   6.346  1.000 19.857 0 197 ASP   A O   1 ? 
ATOM   1512 C CB  . ASP   A 1 197 ? 7.361   0.749   9.286  1.000 19.621 0 197 ASP   A CB  1 ? 
ATOM   1513 C CG  . ASP   A 1 197 ? 8.306   0.644   10.471 1.000 21.130 0 197 ASP   A CG  1 ? 
ATOM   1514 O OD1 . ASP   A 1 197 ? 9.000   1.647   10.731 1.000 22.896 0 197 ASP   A OD1 1 ? 
ATOM   1515 O OD2 . ASP   A 1 197 ? 8.316   -0.408  11.149 1.000 21.278 0 197 ASP   A OD2 1 ? 
ATOM   1516 N N   . THR   A 1 198 ? 10.082  1.838   8.095  1.000 21.394 0 198 THR   A N   1 ? 
ATOM   1517 C CA  . THR   A 1 198 ? 11.358  1.515   7.478  1.000 19.497 0 198 THR   A CA  1 ? 
ATOM   1518 C C   . THR   A 1 198 ? 12.135  0.543   8.371  1.000 19.015 0 198 THR   A C   1 ? 
ATOM   1519 O O   . THR   A 1 198 ? 11.774  0.330   9.531  1.000 17.126 0 198 THR   A O   1 ? 
ATOM   1520 C CB  . THR   A 1 198 ? 12.123  2.801   7.169  1.000 20.498 0 198 THR   A CB  1 ? 
ATOM   1521 O OG1 . THR   A 1 198 ? 12.071  3.649   8.306  1.000 20.756 0 198 THR   A OG1 1 ? 
ATOM   1522 C CG2 . THR   A 1 198 ? 11.542  3.545   5.987  1.000 24.071 0 198 THR   A CG2 1 ? 
ATOM   1523 N N   . THR   A 1 199 ? 13.167  -0.077  7.779  1.000 18.125 0 199 THR   A N   1 ? 
ATOM   1524 C CA  . THR   A 1 199 ? 14.038  -1.028  8.451  1.000 16.595 0 199 THR   A CA  1 ? 
ATOM   1525 C C   . THR   A 1 199 ? 15.189  -0.269  9.119  1.000 15.661 0 199 THR   A C   1 ? 
ATOM   1526 O O   . THR   A 1 199 ? 15.763  0.639   8.512  1.000 16.251 0 199 THR   A O   1 ? 
ATOM   1527 C CB  . THR   A 1 199 ? 14.609  -2.039  7.450  1.000 16.448 0 199 THR   A CB  1 ? 
ATOM   1528 O OG1 . THR   A 1 199 ? 13.514  -2.719  6.850  1.000 17.215 0 199 THR   A OG1 1 ? 
ATOM   1529 C CG2 . THR   A 1 199 ? 15.531  -3.060  8.087  1.000 16.397 0 199 THR   A CG2 1 ? 
ATOM   1530 N N   . ILE   A 1 200 ? 15.524  -0.666  10.352 1.000 13.984 0 200 ILE   A N   1 ? 
ATOM   1531 C CA  . ILE   A 1 200 ? 16.532  -0.011  11.175 1.000 12.984 0 200 ILE   A CA  1 ? 
ATOM   1532 C C   . ILE   A 1 200 ? 17.892  -0.594  10.797 1.000 12.588 0 200 ILE   A C   1 ? 
ATOM   1533 O O   . ILE   A 1 200 ? 18.372  -1.581  11.376 1.000 12.183 0 200 ILE   A O   1 ? 
ATOM   1534 C CB  . ILE   A 1 200 ? 16.203  -0.156  12.680 1.000 13.676 0 200 ILE   A CB  1 ? 
ATOM   1535 C CG1 . ILE   A 1 200 ? 14.740  0.168   13.001 1.000 13.222 0 200 ILE   A CG1 1 ? 
ATOM   1536 C CG2 . ILE   A 1 200 ? 17.126  0.726   13.516 1.000 14.172 0 200 ILE   A CG2 1 ? 
ATOM   1537 C CD1 . ILE   A 1 200 ? 14.173  -0.609  14.175 1.000 12.766 0 200 ILE   A CD1 1 ? 
ATOM   1538 N N   . THR   A 1 201 ? 18.496  0.050   9.790  1.000 12.968 0 201 THR   A N   1 ? 
ATOM   1539 C CA  . THR   A 1 201 ? 19.739  -0.364  9.167  1.000 13.066 0 201 THR   A CA  1 ? 
ATOM   1540 C C   . THR   A 1 201 ? 20.860  -0.643  10.170 1.000 12.452 0 201 THR   A C   1 ? 
ATOM   1541 O O   . THR   A 1 201 ? 21.537  -1.654  10.039 1.000 13.710 0 201 THR   A O   1 ? 
ATOM   1542 C CB  . THR   A 1 201 ? 20.191  0.705   8.172  1.000 13.257 0 201 THR   A CB  1 ? 
ATOM   1543 O OG1 . THR   A 1 201 ? 19.078  0.999   7.328  1.000 14.565 0 201 THR   A OG1 1 ? 
ATOM   1544 C CG2 . THR   A 1 201 ? 21.376  0.271   7.348  1.000 13.403 0 201 THR   A CG2 1 ? 
ATOM   1545 N N   . VAL   A 1 202 ? 21.145  0.284   11.083 1.000 10.944 0 202 VAL   A N   1 ? 
ATOM   1546 C CA  . VAL   A 1 202 ? 22.188  0.048   12.079 1.000 11.389 0 202 VAL   A CA  1 ? 
ATOM   1547 C C   . VAL   A 1 202 ? 21.929  -1.261  12.857 1.000 10.888 0 202 VAL   A C   1 ? 
ATOM   1548 O O   . VAL   A 1 202 ? 22.883  -1.963  13.193 1.000 10.730 0 202 VAL   A O   1 ? 
ATOM   1549 C CB  . VAL   A 1 202 ? 22.366  1.264   13.015 1.000 11.053 0 202 VAL   A CB  1 ? 
ATOM   1550 C CG1 . VAL   A 1 202 ? 21.131  1.552   13.848 1.000 11.596 0 202 VAL   A CG1 1 ? 
ATOM   1551 C CG2 . VAL   A 1 202 ? 23.569  1.116   13.919 1.000 11.446 0 202 VAL   A CG2 1 ? 
ATOM   1552 N N   . ASN   A 1 203 ? 20.650  -1.598  13.142 1.000 10.577 0 203 ASN   A N   1 ? 
ATOM   1553 C CA  . ASN   A 1 203 ? 20.313  -2.817  13.874 1.000 9.855  0 203 ASN   A CA  1 ? 
ATOM   1554 C C   . ASN   A 1 203 ? 20.553  -4.041  12.990 1.000 9.874  0 203 ASN   A C   1 ? 
ATOM   1555 O O   . ASN   A 1 203 ? 21.057  -5.051  13.451 1.000 10.181 0 203 ASN   A O   1 ? 
ATOM   1556 C CB  . ASN   A 1 203 ? 18.874  -2.816  14.410 1.000 9.797  0 203 ASN   A CB  1 ? 
ATOM   1557 C CG  . ASN   A 1 203 ? 18.599  -1.846  15.534 1.000 9.143  0 203 ASN   A CG  1 ? 
ATOM   1558 O OD1 . ASN   A 1 203 ? 17.483  -1.791  16.049 1.000 11.994 0 203 ASN   A OD1 1 ? 
ATOM   1559 N ND2 . ASN   A 1 203 ? 19.564  -1.069  15.939 1.000 8.483  0 203 ASN   A ND2 1 ? 
ATOM   1560 N N   . VAL   A 1 204 ? 20.212  -3.960  11.707 1.000 10.381 0 204 VAL   A N   1 ? 
ATOM   1561 C CA  . VAL   A 1 204 ? 20.489  -5.049  10.777 1.000 11.326 0 204 VAL   A CA  1 ? 
ATOM   1562 C C   . VAL   A 1 204 ? 21.986  -5.354  10.753 1.000 11.797 0 204 VAL   A C   1 ? 
ATOM   1563 O O   . VAL   A 1 204 ? 22.363  -6.527  10.786 1.000 11.058 0 204 VAL   A O   1 ? 
ATOM   1564 C CB  . VAL   A 1 204 ? 19.945  -4.815  9.358  1.000 10.749 0 204 VAL   A CB  1 ? 
ATOM   1565 C CG1 . VAL   A 1 204 ? 20.385  -5.896  8.369  1.000 10.306 0 204 VAL   A CG1 1 ? 
ATOM   1566 C CG2 . VAL   A 1 204 ? 18.434  -4.743  9.378  1.000 10.939 0 204 VAL   A CG2 1 ? 
ATOM   1567 N N   . LEU   A 1 205 ? 22.810  -4.306  10.706 1.000 11.463 0 205 LEU   A N   1 ? 
ATOM   1568 C CA  . LEU   A 1 205 ? 24.250  -4.509  10.723 1.000 12.644 0 205 LEU   A CA  1 ? 
ATOM   1569 C C   . LEU   A 1 205 ? 24.693  -5.144  12.055 1.000 12.798 0 205 LEU   A C   1 ? 
ATOM   1570 O O   . LEU   A 1 205 ? 25.566  -6.008  12.069 1.000 14.404 0 205 LEU   A O   1 ? 
ATOM   1571 C CB  . LEU   A 1 205 ? 24.938  -3.169  10.443 1.000 12.708 0 205 LEU   A CB  1 ? 
ATOM   1572 C CG  . LEU   A 1 205 ? 24.679  -2.612  9.044  1.000 12.994 0 205 LEU   A CG  1 ? 
ATOM   1573 C CD1 . LEU   A 1 205 ? 25.159  -1.195  8.916  1.000 13.223 0 205 LEU   A CD1 1 ? 
ATOM   1574 C CD2 . LEU   A 1 205 ? 25.358  -3.451  7.981  1.000 14.733 0 205 LEU   A CD2 1 ? 
ATOM   1575 N N   . ALA   A 1 206 ? 24.073  -4.770  13.174 1.000 12.382 0 206 ALA   A N   1 ? 
ATOM   1576 C CA  . ALA   A 1 206 ? 24.467  -5.340  14.452 1.000 11.926 0 206 ALA   A CA  1 ? 
ATOM   1577 C C   . ALA   A 1 206 ? 24.195  -6.838  14.419 1.000 12.060 0 206 ALA   A C   1 ? 
ATOM   1578 O O   . ALA   A 1 206 ? 25.000  -7.635  14.880 1.000 10.777 0 206 ALA   A O   1 ? 
ATOM   1579 C CB  . ALA   A 1 206 ? 23.753  -4.677  15.588 1.000 11.462 0 206 ALA   A CB  1 ? 
ATOM   1580 N N   . TRP   A 1 207 ? 23.072  -7.193  13.799 1.000 11.801 0 207 TRP   A N   1 ? 
ATOM   1581 C CA  . TRP   A 1 207 ? 22.656  -8.572  13.756 1.000 12.467 0 207 TRP   A CA  1 ? 
ATOM   1582 C C   . TRP   A 1 207 ? 23.508  -9.366  12.762 1.000 11.946 0 207 TRP   A C   1 ? 
ATOM   1583 O O   . TRP   A 1 207 ? 23.805  -10.518 13.035 1.000 11.743 0 207 TRP   A O   1 ? 
ATOM   1584 C CB  . TRP   A 1 207 ? 21.169  -8.590  13.440 1.000 12.980 0 207 TRP   A CB  1 ? 
ATOM   1585 C CG  . TRP   A 1 207 ? 20.545  -9.931  13.250 1.000 13.953 0 207 TRP   A CG  1 ? 
ATOM   1586 C CD1 . TRP   A 1 207 ? 20.062  -10.748 14.228 1.000 14.346 0 207 TRP   A CD1 1 ? 
ATOM   1587 C CD2 . TRP   A 1 207 ? 20.249  -10.570 12.001 1.000 14.399 0 207 TRP   A CD2 1 ? 
ATOM   1588 N NE1 . TRP   A 1 207 ? 19.475  -11.843 13.677 1.000 13.906 0 207 TRP   A NE1 1 ? 
ATOM   1589 C CE2 . TRP   A 1 207 ? 19.582  -11.775 12.320 1.000 14.860 0 207 TRP   A CE2 1 ? 
ATOM   1590 C CE3 . TRP   A 1 207 ? 20.479  -10.259 10.659 1.000 15.076 0 207 TRP   A CE3 1 ? 
ATOM   1591 C CZ2 . TRP   A 1 207 ? 19.139  -12.660 11.344 1.000 15.066 0 207 TRP   A CZ2 1 ? 
ATOM   1592 C CZ3 . TRP   A 1 207 ? 20.052  -11.145 9.694  1.000 14.889 0 207 TRP   A CZ3 1 ? 
ATOM   1593 C CH2 . TRP   A 1 207 ? 19.390  -12.326 10.034 1.000 15.753 0 207 TRP   A CH2 1 ? 
ATOM   1594 N N   . LEU   A 1 208 ? 23.965  -8.762  11.659 1.000 11.019 0 208 LEU   A N   1 ? 
ATOM   1595 C CA  . LEU   A 1 208 ? 24.934  -9.447  10.814 1.000 11.625 0 208 LEU   A CA  1 ? 
ATOM   1596 C C   . LEU   A 1 208 ? 26.216  -9.764  11.600 1.000 12.274 0 208 LEU   A C   1 ? 
ATOM   1597 O O   . LEU   A 1 208 ? 26.775  -10.819 11.427 1.000 12.228 0 208 LEU   A O   1 ? 
ATOM   1598 C CB  . LEU   A 1 208 ? 25.192  -8.606  9.567  1.000 12.372 0 208 LEU   A CB  1 ? 
ATOM   1599 C CG  . LEU   A 1 208 ? 24.015  -8.534  8.586  1.000 12.766 0 208 LEU   A CG  1 ? 
ATOM   1600 C CD1 . LEU   A 1 208 ? 24.340  -7.643  7.429  1.000 13.561 0 208 LEU   A CD1 1 ? 
ATOM   1601 C CD2 . LEU   A 1 208 ? 23.612  -9.909  8.074  1.000 12.540 0 208 LEU   A CD2 1 ? 
ATOM   1602 N N   . TYR   A 1 209 ? 26.644  -8.878  12.504 1.000 12.904 0 209 TYR   A N   1 ? 
ATOM   1603 C CA  . TYR   A 1 209 ? 27.781  -9.114  13.369 1.000 13.524 0 209 TYR   A CA  1 ? 
ATOM   1604 C C   . TYR   A 1 209 ? 27.497  -10.255 14.341 1.000 14.602 0 209 TYR   A C   1 ? 
ATOM   1605 O O   . TYR   A 1 209 ? 28.389  -11.052 14.627 1.000 13.498 0 209 TYR   A O   1 ? 
ATOM   1606 C CB  . TYR   A 1 209 ? 28.151  -7.843  14.128 1.000 12.815 0 209 TYR   A CB  1 ? 
ATOM   1607 C CG  . TYR   A 1 209 ? 29.046  -6.949  13.302 1.000 13.339 0 209 TYR   A CG  1 ? 
ATOM   1608 C CD1 . TYR   A 1 209 ? 30.364  -7.305  13.016 1.000 14.048 0 209 TYR   A CD1 1 ? 
ATOM   1609 C CD2 . TYR   A 1 209 ? 28.560  -5.761  12.780 1.000 13.868 0 209 TYR   A CD2 1 ? 
ATOM   1610 C CE1 . TYR   A 1 209 ? 31.170  -6.498  12.236 1.000 13.753 0 209 TYR   A CE1 1 ? 
ATOM   1611 C CE2 . TYR   A 1 209 ? 29.350  -4.953  11.990 1.000 13.914 0 209 TYR   A CE2 1 ? 
ATOM   1612 C CZ  . TYR   A 1 209 ? 30.656  -5.320  11.723 1.000 13.981 0 209 TYR   A CZ  1 ? 
ATOM   1613 O OH  . TYR   A 1 209 ? 31.365  -4.503  10.918 1.000 12.785 0 209 TYR   A OH  1 ? 
ATOM   1614 N N   . ALA   A 1 210 ? 26.264  -10.308 14.868 1.000 14.733 0 210 ALA   A N   1 ? 
ATOM   1615 C CA  . ALA   A 1 210 ? 25.879  -11.400 15.740 1.000 14.208 0 210 ALA   A CA  1 ? 
ATOM   1616 C C   . ALA   A 1 210 ? 26.017  -12.704 14.971 1.000 13.583 0 210 ALA   A C   1 ? 
ATOM   1617 O O   . ALA   A 1 210 ? 26.455  -13.694 15.532 1.000 13.280 0 210 ALA   A O   1 ? 
ATOM   1618 C CB  . ALA   A 1 210 ? 24.459  -11.224 16.245 1.000 15.396 0 210 ALA   A CB  1 ? 
ATOM   1619 N N   . ALA   A 1 211 ? 25.591  -12.700 13.708 1.000 13.050 0 211 ALA   A N   1 ? 
ATOM   1620 C CA  . ALA   A 1 211 ? 25.639  -13.904 12.902 1.000 14.005 0 211 ALA   A CA  1 ? 
ATOM   1621 C C   . ALA   A 1 211 ? 27.083  -14.419 12.768 1.000 15.477 0 211 ALA   A C   1 ? 
ATOM   1622 O O   . ALA   A 1 211 ? 27.323  -15.626 12.905 1.000 14.559 0 211 ALA   A O   1 ? 
ATOM   1623 C CB  . ALA   A 1 211 ? 25.002  -13.643 11.565 1.000 13.245 0 211 ALA   A CB  1 ? 
ATOM   1624 N N   . VAL   A 1 212 ? 28.038  -13.506 12.498 1.000 15.378 0 212 VAL   A N   1 ? 
ATOM   1625 C CA  . VAL   A 1 212 ? 29.433  -13.875 12.317 1.000 15.878 0 212 VAL   A CA  1 ? 
ATOM   1626 C C   . VAL   A 1 212 ? 30.012  -14.414 13.627 1.000 16.006 0 212 VAL   A C   1 ? 
ATOM   1627 O O   . VAL   A 1 212 ? 30.698  -15.427 13.608 1.000 14.577 0 212 VAL   A O   1 ? 
ATOM   1628 C CB  . VAL   A 1 212 ? 30.265  -12.700 11.778 1.000 17.514 0 212 VAL   A CB  1 ? 
ATOM   1629 C CG1 . VAL   A 1 212 ? 31.757  -13.021 11.790 1.000 18.921 0 212 VAL   A CG1 1 ? 
ATOM   1630 C CG2 . VAL   A 1 212 ? 29.800  -12.280 10.384 1.000 16.575 0 212 VAL   A CG2 1 ? 
ATOM   1631 N N   . ILE   A 1 213 ? 29.697  -13.766 14.755 1.000 17.338 0 213 ILE   A N   1 ? 
ATOM   1632 C CA  . ILE   A 1 213 ? 30.152  -14.199 16.073 1.000 17.630 0 213 ILE   A CA  1 ? 
ATOM   1633 C C   . ILE   A 1 213 ? 29.676  -15.626 16.336 1.000 17.095 0 213 ILE   A C   1 ? 
ATOM   1634 O O   . ILE   A 1 213 ? 30.396  -16.398 16.947 1.000 15.847 0 213 ILE   A O   1 ? 
ATOM   1635 C CB  . ILE   A 1 213 ? 29.667  -13.228 17.173 1.000 18.365 0 213 ILE   A CB  1 ? 
ATOM   1636 C CG1 . ILE   A 1 213 ? 30.360  -11.867 17.060 1.000 19.155 0 213 ILE   A CG1 1 ? 
ATOM   1637 C CG2 . ILE   A 1 213 ? 29.845  -13.815 18.574 1.000 19.143 0 213 ILE   A CG2 1 ? 
ATOM   1638 C CD1 . ILE   A 1 213 ? 29.660  -10.727 17.791 1.000 17.355 0 213 ILE   A CD1 1 ? 
ATOM   1639 N N   . ASN   A 1 214 ? 28.462  -15.944 15.885 1.000 17.409 0 214 ASN   A N   1 ? 
ATOM   1640 C CA  . ASN   A 1 214 ? 27.849  -17.243 16.098 1.000 20.697 0 214 ASN   A CA  1 ? 
ATOM   1641 C C   . ASN   A 1 214 ? 28.107  -18.181 14.922 1.000 20.040 0 214 ASN   A C   1 ? 
ATOM   1642 O O   . ASN   A 1 214 ? 27.465  -19.219 14.845 1.000 20.391 0 214 ASN   A O   1 ? 
ATOM   1643 C CB  . ASN   A 1 214 ? 26.343  -17.106 16.379 1.000 23.373 0 214 ASN   A CB  1 ? 
ATOM   1644 C CG  . ASN   A 1 214 ? 26.123  -16.574 17.775 1.000 25.146 0 214 ASN   A CG  1 ? 
ATOM   1645 O OD1 . ASN   A 1 214 ? 26.209  -17.340 18.728 1.000 29.229 0 214 ASN   A OD1 1 ? 
ATOM   1646 N ND2 . ASN   A 1 214 ? 25.974  -15.260 17.913 1.000 23.492 0 214 ASN   A ND2 1 ? 
ATOM   1647 N N   . GLY   A 1 215 ? 29.037  -17.827 14.024 1.000 20.333 0 215 GLY   A N   1 ? 
ATOM   1648 C CA  . GLY   A 1 215 ? 29.578  -18.767 13.045 1.000 19.447 0 215 GLY   A CA  1 ? 
ATOM   1649 C C   . GLY   A 1 215 ? 28.832  -18.827 11.707 1.000 21.020 0 215 GLY   A C   1 ? 
ATOM   1650 O O   . GLY   A 1 215 ? 29.101  -19.731 10.926 1.000 20.298 0 215 GLY   A O   1 ? 
ATOM   1651 N N   . ASP   A 1 216 ? 27.888  -17.905 11.437 1.000 21.373 0 216 ASP   A N   1 ? 
ATOM   1652 C CA  . ASP   A 1 216 ? 27.281  -17.783 10.120 1.000 21.821 0 216 ASP   A CA  1 ? 
ATOM   1653 C C   . ASP   A 1 216 ? 28.032  -16.736 9.320  1.000 21.722 0 216 ASP   A C   1 ? 
ATOM   1654 O O   . ASP   A 1 216 ? 27.921  -15.567 9.658  1.000 24.307 0 216 ASP   A O   1 ? 
ATOM   1655 C CB  . ASP   A 1 216 ? 25.849  -17.265 10.164 1.000 26.224 0 216 ASP   A CB  1 ? 
ATOM   1656 C CG  . ASP   A 1 216 ? 24.762  -18.317 10.145 1.000 30.550 0 216 ASP   A CG  1 ? 
ATOM   1657 O OD1 . ASP   A 1 216 ? 24.874  -19.243 9.337  1.000 39.386 0 216 ASP   A OD1 1 ? 
ATOM   1658 O OD2 . ASP   A 1 216 ? 23.771  -18.141 10.858 1.000 32.253 0 216 ASP   A OD2 1 ? 
ATOM   1659 N N   . ARG   A 1 217 ? 28.696  -17.145 8.224  1.000 21.184 0 217 ARG   A N   1 ? 
ATOM   1660 C CA  . ARG   A 1 217 ? 29.657  -16.304 7.523  1.000 20.838 0 217 ARG   A CA  1 ? 
ATOM   1661 C C   . ARG   A 1 217 ? 29.409  -16.213 6.023  1.000 19.663 0 217 ARG   A C   1 ? 
ATOM   1662 O O   . ARG   A 1 217 ? 30.099  -15.479 5.336  1.000 19.970 0 217 ARG   A O   1 ? 
ATOM   1663 C CB  . ARG   A 1 217 ? 31.065  -16.878 7.689  1.000 21.826 0 217 ARG   A CB  1 ? 
ATOM   1664 C CG  . ARG   A 1 217 ? 31.619  -16.699 9.093  1.000 25.677 0 217 ARG   A CG  1 ? 
ATOM   1665 C CD  . ARG   A 1 217 ? 32.967  -17.389 9.314  1.000 29.588 0 217 ARG   A CD  1 ? 
ATOM   1666 N NE  . ARG   A 1 217 ? 33.678  -16.753 10.422 1.000 32.616 0 217 ARG   A NE  1 ? 
ATOM   1667 C CZ  . ARG   A 1 217 ? 34.433  -15.660 10.300 1.000 32.525 0 217 ARG   A CZ  1 ? 
ATOM   1668 N NH1 . ARG   A 1 217 ? 34.824  -15.225 9.115  1.000 33.846 0 217 ARG   A NH1 1 ? 
ATOM   1669 N NH2 . ARG   A 1 217 ? 34.838  -15.039 11.385 1.000 36.215 0 217 ARG   A NH2 1 ? 
ATOM   1670 N N   . TRP   A 1 218 ? 28.436  -16.948 5.494  1.000 18.823 0 218 TRP   A N   1 ? 
ATOM   1671 C CA  . TRP   A 1 218 ? 28.389  -17.166 4.061  1.000 17.874 0 218 TRP   A CA  1 ? 
ATOM   1672 C C   . TRP   A 1 218 ? 28.166  -15.862 3.286  1.000 17.066 0 218 TRP   A C   1 ? 
ATOM   1673 O O   . TRP   A 1 218 ? 28.418  -15.803 2.086  1.000 14.931 0 218 TRP   A O   1 ? 
ATOM   1674 C CB  . TRP   A 1 218 ? 27.289  -18.200 3.780  1.000 17.654 0 218 TRP   A CB  1 ? 
ATOM   1675 C CG  . TRP   A 1 218 ? 25.895  -17.734 4.136  1.000 17.735 0 218 TRP   A CG  1 ? 
ATOM   1676 C CD1 . TRP   A 1 218 ? 25.156  -18.023 5.256  1.000 18.023 0 218 TRP   A CD1 1 ? 
ATOM   1677 C CD2 . TRP   A 1 218 ? 25.047  -16.919 3.304  1.000 16.760 0 218 TRP   A CD2 1 ? 
ATOM   1678 N NE1 . TRP   A 1 218 ? 23.933  -17.403 5.203  1.000 18.121 0 218 TRP   A NE1 1 ? 
ATOM   1679 C CE2 . TRP   A 1 218 ? 23.827  -16.742 4.002  1.000 18.145 0 218 TRP   A CE2 1 ? 
ATOM   1680 C CE3 . TRP   A 1 218 ? 25.198  -16.343 2.045  1.000 17.332 0 218 TRP   A CE3 1 ? 
ATOM   1681 C CZ2 . TRP   A 1 218 ? 22.777  -16.004 3.466  1.000 18.389 0 218 TRP   A CZ2 1 ? 
ATOM   1682 C CZ3 . TRP   A 1 218 ? 24.156  -15.621 1.509  1.000 17.715 0 218 TRP   A CZ3 1 ? 
ATOM   1683 C CH2 . TRP   A 1 218 ? 22.968  -15.445 2.223  1.000 18.678 0 218 TRP   A CH2 1 ? 
ATOM   1684 N N   . PHE   A 1 219 ? 27.577  -14.849 3.946  1.000 17.162 0 219 PHE   A N   1 ? 
ATOM   1685 C CA  . PHE   A 1 219 ? 27.162  -13.618 3.272  1.000 16.958 0 219 PHE   A CA  1 ? 
ATOM   1686 C C   . PHE   A 1 219 ? 28.325  -12.612 3.200  1.000 15.557 0 219 PHE   A C   1 ? 
ATOM   1687 O O   . PHE   A 1 219 ? 28.199  -11.581 2.563  1.000 14.938 0 219 PHE   A O   1 ? 
ATOM   1688 C CB  . PHE   A 1 219 ? 25.939  -13.043 4.009  1.000 16.574 0 219 PHE   A CB  1 ? 
ATOM   1689 C CG  . PHE   A 1 219 ? 26.182  -12.856 5.485  1.000 15.467 0 219 PHE   A CG  1 ? 
ATOM   1690 C CD1 . PHE   A 1 219 ? 26.864  -11.748 5.957  1.000 15.490 0 219 PHE   A CD1 1 ? 
ATOM   1691 C CD2 . PHE   A 1 219 ? 25.817  -13.842 6.393  1.000 15.366 0 219 PHE   A CD2 1 ? 
ATOM   1692 C CE1 . PHE   A 1 219 ? 27.163  -11.628 7.308  1.000 16.293 0 219 PHE   A CE1 1 ? 
ATOM   1693 C CE2 . PHE   A 1 219 ? 26.096  -13.714 7.745  1.000 15.291 0 219 PHE   A CE2 1 ? 
ATOM   1694 C CZ  . PHE   A 1 219 ? 26.791  -12.622 8.199  1.000 14.704 0 219 PHE   A CZ  1 ? 
ATOM   1695 N N   . LEU   A 1 220 ? 29.447  -12.869 3.882  1.000 16.117 0 220 LEU   A N   1 ? 
ATOM   1696 C CA  . LEU   A 1 220 ? 30.629  -12.012 3.756  1.000 18.909 0 220 LEU   A CA  1 ? 
ATOM   1697 C C   . LEU   A 1 220 ? 31.130  -12.035 2.306  1.000 21.102 0 220 LEU   A C   1 ? 
ATOM   1698 O O   . LEU   A 1 220 ? 31.257  -13.110 1.739  1.000 21.837 0 220 LEU   A O   1 ? 
ATOM   1699 C CB  . LEU   A 1 220 ? 31.729  -12.501 4.702  1.000 19.485 0 220 LEU   A CB  1 ? 
ATOM   1700 C CG  . LEU   A 1 220 ? 31.418  -12.423 6.205  1.000 19.592 0 220 LEU   A CG  1 ? 
ATOM   1701 C CD1 . LEU   A 1 220 ? 32.596  -12.931 7.035  1.000 19.620 0 220 LEU   A CD1 1 ? 
ATOM   1702 C CD2 . LEU   A 1 220 ? 31.056  -10.995 6.618  1.000 19.685 0 220 LEU   A CD2 1 ? 
ATOM   1703 N N   . ASN   A 1 221 ? 31.369  -10.858 1.698  1.000 21.393 0 221 ASN   A N   1 ? 
ATOM   1704 C CA  . ASN   A 1 221 ? 31.848  -10.778 0.323  1.000 21.529 0 221 ASN   A CA  1 ? 
ATOM   1705 C C   . ASN   A 1 221 ? 33.202  -10.064 0.296  1.000 20.928 0 221 ASN   A C   1 ? 
ATOM   1706 O O   . ASN   A 1 221 ? 33.751  -9.685  1.324  1.000 19.718 0 221 ASN   A O   1 ? 
ATOM   1707 C CB  . ASN   A 1 221 ? 30.770  -10.196 -0.607 1.000 21.997 0 221 ASN   A CB  1 ? 
ATOM   1708 C CG  . ASN   A 1 221 ? 30.504  -8.710  -0.452 1.000 22.553 0 221 ASN   A CG  1 ? 
ATOM   1709 O OD1 . ASN   A 1 221 ? 31.304  -7.954  0.092  1.000 21.200 0 221 ASN   A OD1 1 ? 
ATOM   1710 N ND2 . ASN   A 1 221 ? 29.415  -8.252  -1.041 1.000 24.736 0 221 ASN   A ND2 1 ? 
ATOM   1711 N N   . ARG   A 1 222 ? 33.761  -9.903  -0.903 1.000 22.277 0 222 ARG   A N   1 ? 
ATOM   1712 C CA  . ARG   A 1 222 ? 35.123  -9.418  -1.076 1.000 22.854 0 222 ARG   A CA  1 ? 
ATOM   1713 C C   . ARG   A 1 222 ? 35.131  -7.900  -1.289 1.000 22.433 0 222 ARG   A C   1 ? 
ATOM   1714 O O   . ARG   A 1 222 ? 36.158  -7.337  -1.657 1.000 22.156 0 222 ARG   A O   1 ? 
ATOM   1715 C CB  . ARG   A 1 222 ? 35.776  -10.136 -2.273 1.000 24.855 0 222 ARG   A CB  1 ? 
ATOM   1716 C CG  . ARG   A 1 222 ? 35.198  -9.788  -3.647 1.000 27.410 0 222 ARG   A CG  1 ? 
ATOM   1717 C CD  . ARG   A 1 222 ? 35.762  -10.633 -4.796 1.000 31.717 0 222 ARG   A CD  1 ? 
ATOM   1718 N NE  . ARG   A 1 222 ? 35.279  -10.317 -6.149 1.000 32.072 0 222 ARG   A NE  1 ? 
ATOM   1719 C CZ  . ARG   A 1 222 ? 35.580  -9.215  -6.846 1.000 37.749 0 222 ARG   A CZ  1 ? 
ATOM   1720 N NH1 . ARG   A 1 222 ? 34.978  -8.968  -8.002 1.000 38.602 0 222 ARG   A NH1 1 ? 
ATOM   1721 N NH2 . ARG   A 1 222 ? 36.442  -8.324  -6.378 1.000 38.470 0 222 ARG   A NH2 1 ? 
ATOM   1722 N N   . PHE   A 1 223 ? 33.991  -7.229  -1.083 1.000 19.205 0 223 PHE   A N   1 ? 
ATOM   1723 C CA  . PHE   A 1 223 ? 33.871  -5.837  -1.466 1.000 19.059 0 223 PHE   A CA  1 ? 
ATOM   1724 C C   . PHE   A 1 223 ? 33.861  -4.932  -0.242 1.000 17.411 0 223 PHE   A C   1 ? 
ATOM   1725 O O   . PHE   A 1 223 ? 33.541  -5.362  0.854  1.000 15.956 0 223 PHE   A O   1 ? 
ATOM   1726 C CB  . PHE   A 1 223 ? 32.611  -5.641  -2.305 1.000 21.042 0 223 PHE   A CB  1 ? 
ATOM   1727 C CG  . PHE   A 1 223 ? 32.667  -6.246  -3.686 1.000 25.151 0 223 PHE   A CG  1 ? 
ATOM   1728 C CD1 . PHE   A 1 223 ? 33.418  -5.652  -4.689 1.000 27.442 0 223 PHE   A CD1 1 ? 
ATOM   1729 C CD2 . PHE   A 1 223 ? 31.985  -7.417  -3.976 1.000 28.943 0 223 PHE   A CD2 1 ? 
ATOM   1730 C CE1 . PHE   A 1 223 ? 33.459  -6.198  -5.964 1.000 30.153 0 223 PHE   A CE1 1 ? 
ATOM   1731 C CE2 . PHE   A 1 223 ? 32.039  -7.975  -5.246 1.000 30.928 0 223 PHE   A CE2 1 ? 
ATOM   1732 C CZ  . PHE   A 1 223 ? 32.779  -7.367  -6.235 1.000 31.589 0 223 PHE   A CZ  1 ? 
ATOM   1733 N N   . THR   A 1 224 ? 34.147  -3.650  -0.456 1.000 16.673 0 224 THR   A N   1 ? 
ATOM   1734 C CA  . THR   A 1 224 ? 33.789  -2.619  0.497  1.000 17.694 0 224 THR   A CA  1 ? 
ATOM   1735 C C   . THR   A 1 224 ? 32.879  -1.633  -0.233 1.000 19.329 0 224 THR   A C   1 ? 
ATOM   1736 O O   . THR   A 1 224 ? 32.524  -1.829  -1.406 1.000 18.308 0 224 THR   A O   1 ? 
ATOM   1737 C CB  . THR   A 1 224 ? 35.046  -2.038  1.170  1.000 19.777 0 224 THR   A CB  1 ? 
ATOM   1738 O OG1 . THR   A 1 224 ? 34.661  -1.231  2.292  1.000 19.056 0 224 THR   A OG1 1 ? 
ATOM   1739 C CG2 . THR   A 1 224 ? 35.895  -1.195  0.245  1.000 21.223 0 224 THR   A CG2 1 ? 
ATOM   1740 N N   . THR   A 1 225 ? 32.409  -0.625  0.500  1.000 19.461 0 225 THR   A N   1 ? 
ATOM   1741 C CA  . THR   A 1 225 ? 31.526  0.389   -0.061 1.000 19.063 0 225 THR   A CA  1 ? 
ATOM   1742 C C   . THR   A 1 225 ? 31.825  1.679   0.687  1.000 20.392 0 225 THR   A C   1 ? 
ATOM   1743 O O   . THR   A 1 225 ? 32.350  1.658   1.803  1.000 19.238 0 225 THR   A O   1 ? 
ATOM   1744 C CB  . THR   A 1 225 ? 30.041  -0.001  0.066  1.000 19.284 0 225 THR   A CB  1 ? 
ATOM   1745 O OG1 . THR   A 1 225 ? 29.185  0.954   -0.577 1.000 18.360 0 225 THR   A OG1 1 ? 
ATOM   1746 C CG2 . THR   A 1 225 ? 29.594  -0.129  1.505  1.000 18.847 0 225 THR   A CG2 1 ? 
ATOM   1747 N N   . THR   A 1 226 ? 31.484  2.802   0.063  1.000 21.955 0 226 THR   A N   1 ? 
ATOM   1748 C CA  . THR   A 1 226 ? 31.400  4.053   0.793  1.000 21.794 0 226 THR   A CA  1 ? 
ATOM   1749 C C   . THR   A 1 226 ? 30.032  4.102   1.476  1.000 20.766 0 226 THR   A C   1 ? 
ATOM   1750 O O   . THR   A 1 226 ? 29.076  3.420   1.087  1.000 18.756 0 226 THR   A O   1 ? 
ATOM   1751 C CB  . THR   A 1 226 ? 31.656  5.239   -0.152 1.000 24.174 0 226 THR   A CB  1 ? 
ATOM   1752 O OG1 . THR   A 1 226 ? 30.559  5.318   -1.052 1.000 21.128 0 226 THR   A OG1 1 ? 
ATOM   1753 C CG2 . THR   A 1 226 ? 32.947  5.115   -0.955 1.000 24.612 0 226 THR   A CG2 1 ? 
ATOM   1754 N N   . LEU   A 1 227 ? 29.945  4.970   2.472  1.000 21.126 0 227 LEU   A N   1 ? 
ATOM   1755 C CA  . LEU   A 1 227 ? 28.695  5.249   3.137  1.000 24.644 0 227 LEU   A CA  1 ? 
ATOM   1756 C C   . LEU   A 1 227 ? 27.649  5.769   2.151  1.000 24.722 0 227 LEU   A C   1 ? 
ATOM   1757 O O   . LEU   A 1 227 ? 26.502  5.335   2.232  1.000 23.548 0 227 LEU   A O   1 ? 
ATOM   1758 C CB  . LEU   A 1 227 ? 28.963  6.235   4.275  1.000 25.026 0 227 LEU   A CB  1 ? 
ATOM   1759 C CG  . LEU   A 1 227 ? 27.831  6.376   5.294  1.000 27.419 0 227 LEU   A CG  1 ? 
ATOM   1760 C CD1 . LEU   A 1 227 ? 27.383  5.026   5.850  1.000 28.133 0 227 LEU   A CD1 1 ? 
ATOM   1761 C CD2 . LEU   A 1 227 ? 28.269  7.269   6.435  1.000 27.635 0 227 LEU   A CD2 1 ? 
ATOM   1762 N N   . ASN   A 1 228 ? 28.042  6.689   1.248  1.000 23.193 0 228 ASN   A N   1 ? 
ATOM   1763 C CA  . ASN   A 1 228 ? 27.117  7.263   0.281  1.000 24.633 0 228 ASN   A CA  1 ? 
ATOM   1764 C C   . ASN   A 1 228 ? 26.595  6.166   -0.640 1.000 22.953 0 228 ASN   A C   1 ? 
ATOM   1765 O O   . ASN   A 1 228 ? 25.398  6.085   -0.853 1.000 21.890 0 228 ASN   A O   1 ? 
ATOM   1766 C CB  . ASN   A 1 228 ? 27.700  8.367   -0.618 1.000 25.680 0 228 ASN   A CB  1 ? 
ATOM   1767 C CG  . ASN   A 1 228 ? 26.706  8.778   -1.700 1.000 30.701 0 228 ASN   A CG  1 ? 
ATOM   1768 O OD1 . ASN   A 1 228 ? 25.712  9.452   -1.427 1.000 32.210 0 228 ASN   A OD1 1 ? 
ATOM   1769 N ND2 . ASN   A 1 228 ? 26.920  8.334   -2.929 1.000 31.506 0 228 ASN   A ND2 1 ? 
ATOM   1770 N N   . ASP   A 1 229 ? 27.488  5.337   -1.193 1.000 23.520 0 229 ASP   A N   1 ? 
ATOM   1771 C CA  . ASP   A 1 229 ? 27.055  4.281   -2.103 1.000 26.677 0 229 ASP   A CA  1 ? 
ATOM   1772 C C   . ASP   A 1 229 ? 26.178  3.268   -1.363 1.000 23.122 0 229 ASP   A C   1 ? 
ATOM   1773 O O   . ASP   A 1 229 ? 25.262  2.695   -1.939 1.000 22.193 0 229 ASP   A O   1 ? 
ATOM   1774 C CB  . ASP   A 1 229 ? 28.232  3.574   -2.777 1.000 31.755 0 229 ASP   A CB  1 ? 
ATOM   1775 C CG  . ASP   A 1 229 ? 28.894  4.395   -3.876 1.000 38.932 0 229 ASP   A CG  1 ? 
ATOM   1776 O OD1 . ASP   A 1 229 ? 28.336  5.475   -4.221 1.000 41.010 0 229 ASP   A OD1 1 ? 
ATOM   1777 O OD2 . ASP   A 1 229 ? 29.965  3.951   -4.383 1.000 36.966 0 229 ASP   A OD2 1 ? 
ATOM   1778 N N   . PHE   A 1 230 ? 26.449  3.046   -0.075 1.000 19.642 0 230 PHE   A N   1 ? 
ATOM   1779 C CA  . PHE   A 1 230 ? 25.620  2.129   0.670  1.000 17.578 0 230 PHE   A CA  1 ? 
ATOM   1780 C C   . PHE   A 1 230 ? 24.197  2.695   0.758  1.000 16.278 0 230 PHE   A C   1 ? 
ATOM   1781 O O   . PHE   A 1 230 ? 23.239  2.039   0.382  1.000 13.063 0 230 PHE   A O   1 ? 
ATOM   1782 C CB  . PHE   A 1 230 ? 26.240  1.813   2.031  1.000 17.813 0 230 PHE   A CB  1 ? 
ATOM   1783 C CG  . PHE   A 1 230 ? 25.262  1.048   2.867  1.000 19.896 0 230 PHE   A CG  1 ? 
ATOM   1784 C CD1 . PHE   A 1 230 ? 25.086  -0.313  2.667  1.000 18.661 0 230 PHE   A CD1 1 ? 
ATOM   1785 C CD2 . PHE   A 1 230 ? 24.407  1.719   3.731  1.000 20.900 0 230 PHE   A CD2 1 ? 
ATOM   1786 C CE1 . PHE   A 1 230 ? 24.145  -1.009  3.405  1.000 20.701 0 230 PHE   A CE1 1 ? 
ATOM   1787 C CE2 . PHE   A 1 230 ? 23.442  1.022   4.445  1.000 20.341 0 230 PHE   A CE2 1 ? 
ATOM   1788 C CZ  . PHE   A 1 230 ? 23.308  -0.336  4.273  1.000 19.813 0 230 PHE   A CZ  1 ? 
ATOM   1789 N N   . ASN   A 1 231 ? 24.059  3.950   1.185  1.000 17.616 0 231 ASN   A N   1 ? 
ATOM   1790 C CA  . ASN   A 1 231 ? 22.754  4.600   1.333  1.000 17.905 0 231 ASN   A CA  1 ? 
ATOM   1791 C C   . ASN   A 1 231 ? 21.946  4.694   0.032  1.000 20.139 0 231 ASN   A C   1 ? 
ATOM   1792 O O   . ASN   A 1 231 ? 20.722  4.600   0.058  1.000 21.018 0 231 ASN   A O   1 ? 
ATOM   1793 C CB  . ASN   A 1 231 ? 22.927  5.976   1.981  1.000 17.099 0 231 ASN   A CB  1 ? 
ATOM   1794 C CG  . ASN   A 1 231 ? 23.179  5.790   3.462  1.000 18.383 0 231 ASN   A CG  1 ? 
ATOM   1795 O OD1 . ASN   A 1 231 ? 22.624  4.860   4.050  1.000 19.408 0 231 ASN   A OD1 1 ? 
ATOM   1796 N ND2 . ASN   A 1 231 ? 24.043  6.591   4.060  1.000 17.957 0 231 ASN   A ND2 1 ? 
ATOM   1797 N N   . LEU   A 1 232 ? 22.613  4.908   -1.097 1.000 21.920 0 232 LEU   A N   1 ? 
ATOM   1798 C CA  . LEU   A 1 232 ? 21.943  4.959   -2.392 1.000 26.363 0 232 LEU   A CA  1 ? 
ATOM   1799 C C   . LEU   A 1 232 ? 21.164  3.666   -2.600 1.000 26.671 0 232 LEU   A C   1 ? 
ATOM   1800 O O   . LEU   A 1 232 ? 20.047  3.697   -3.093 1.000 24.990 0 232 LEU   A O   1 ? 
ATOM   1801 C CB  . LEU   A 1 232 ? 22.993  5.132   -3.498 1.000 30.650 0 232 LEU   A CB  1 ? 
ATOM   1802 C CG  . LEU   A 1 232 ? 23.091  6.483   -4.220 1.000 36.119 0 232 LEU   A CG  1 ? 
ATOM   1803 C CD1 . LEU   A 1 232 ? 22.706  7.663   -3.341 1.000 38.319 0 232 LEU   A CD1 1 ? 
ATOM   1804 C CD2 . LEU   A 1 232 ? 24.496  6.674   -4.778 1.000 33.396 0 232 LEU   A CD2 1 ? 
ATOM   1805 N N   . VAL   A 1 233 ? 21.757  2.528   -2.197 1.000 26.451 0 233 VAL   A N   1 ? 
ATOM   1806 C CA  . VAL   A 1 233 ? 21.148  1.230   -2.424 1.000 22.641 0 233 VAL   A CA  1 ? 
ATOM   1807 C C   . VAL   A 1 233 ? 20.060  1.009   -1.382 1.000 23.738 0 233 VAL   A C   1 ? 
ATOM   1808 O O   . VAL   A 1 233 ? 18.946  0.647   -1.733 1.000 20.223 0 233 VAL   A O   1 ? 
ATOM   1809 C CB  . VAL   A 1 233 ? 22.194  0.104   -2.443 1.000 21.935 0 233 VAL   A CB  1 ? 
ATOM   1810 C CG1 . VAL   A 1 233 ? 21.538  -1.272  -2.521 1.000 22.622 0 233 VAL   A CG1 1 ? 
ATOM   1811 C CG2 . VAL   A 1 233 ? 23.165  0.287   -3.591 1.000 23.030 0 233 VAL   A CG2 1 ? 
ATOM   1812 N N   . ALA   A 1 234 ? 20.360  1.355   -0.125 1.000 25.258 0 234 ALA   A N   1 ? 
ATOM   1813 C CA  . ALA   A 1 234 ? 19.462  1.129   0.998  1.000 27.715 0 234 ALA   A CA  1 ? 
ATOM   1814 C C   . ALA   A 1 234 ? 18.162  1.943   0.927  1.000 25.321 0 234 ALA   A C   1 ? 
ATOM   1815 O O   . ALA   A 1 234 ? 17.119  1.401   1.287  1.000 25.201 0 234 ALA   A O   1 ? 
ATOM   1816 C CB  . ALA   A 1 234 ? 20.191  1.402   2.297  1.000 30.000 0 234 ALA   A CB  1 ? 
ATOM   1817 N N   . MET   A 1 235 ? 18.218  3.212   0.494  1.000 27.129 0 235 MET   A N   1 ? 
ATOM   1818 C CA  . MET   A 1 235 ? 17.037  4.054   0.335  1.000 29.069 0 235 MET   A CA  1 ? 
ATOM   1819 C C   . MET   A 1 235 ? 16.038  3.349   -0.589 1.000 29.296 0 235 MET   A C   1 ? 
ATOM   1820 O O   . MET   A 1 235 ? 14.825  3.500   -0.455 1.000 28.785 0 235 MET   A O   1 ? 
ATOM   1821 C CB  . MET   A 1 235 ? 17.384  5.408   -0.291 1.000 36.288 0 235 MET   A CB  1 ? 
ATOM   1822 C CG  . MET   A 1 235 ? 18.143  6.388   0.631  1.000 48.320 0 235 MET   A CG  1 ? 
ATOM   1823 S SD  . MET   A 1 235 ? 17.172  7.302   1.900  1.000 61.621 0 235 MET   A SD  1 ? 
ATOM   1824 C CE  . MET   A 1 235 ? 15.698  7.784   0.999  1.000 61.296 0 235 MET   A CE  1 ? 
ATOM   1825 N N   . LYS   A 1 236 ? 16.572  2.540   -1.509 1.000 24.684 0 236 LYS   A N   1 ? 
ATOM   1826 C CA  . LYS   A 1 236 ? 15.769  1.887   -2.520 1.000 27.096 0 236 LYS   A CA  1 ? 
ATOM   1827 C C   . LYS   A 1 236 ? 15.023  0.683   -1.928 1.000 22.686 0 236 LYS   A C   1 ? 
ATOM   1828 O O   . LYS   A 1 236 ? 14.082  0.194   -2.552 1.000 20.924 0 236 LYS   A O   1 ? 
ATOM   1829 C CB  . LYS   A 1 236 ? 16.662  1.593   -3.737 1.000 32.677 0 236 LYS   A CB  1 ? 
ATOM   1830 C CG  . LYS   A 1 236 ? 16.195  0.437   -4.611 1.000 43.428 0 236 LYS   A CG  1 ? 
ATOM   1831 C CD  . LYS   A 1 236 ? 16.963  0.208   -5.905 1.000 50.513 0 236 LYS   A CD  1 ? 
ATOM   1832 C CE  . LYS   A 1 236 ? 16.329  -0.911  -6.715 1.000 56.032 0 236 LYS   A CE  1 ? 
ATOM   1833 N NZ  . LYS   A 1 236 ? 16.814  -0.935  -8.114 1.000 59.808 0 236 LYS   A NZ  1 ? 
ATOM   1834 N N   . TYR   A 1 237 ? 15.405  0.210   -0.727 1.000 19.899 0 237 TYR   A N   1 ? 
ATOM   1835 C CA  . TYR   A 1 237 ? 14.728  -0.922  -0.118 1.000 19.956 0 237 TYR   A CA  1 ? 
ATOM   1836 C C   . TYR   A 1 237 ? 14.068  -0.539  1.205  1.000 18.129 0 237 TYR   A C   1 ? 
ATOM   1837 O O   . TYR   A 1 237 ? 13.852  -1.424  2.042  1.000 18.320 0 237 TYR   A O   1 ? 
ATOM   1838 C CB  . TYR   A 1 237 ? 15.665  -2.124  0.081  1.000 21.610 0 237 TYR   A CB  1 ? 
ATOM   1839 C CG  . TYR   A 1 237 ? 16.160  -2.654  -1.253 1.000 21.823 0 237 TYR   A CG  1 ? 
ATOM   1840 C CD1 . TYR   A 1 237 ? 17.256  -2.077  -1.879 1.000 22.324 0 237 TYR   A CD1 1 ? 
ATOM   1841 C CD2 . TYR   A 1 237 ? 15.509  -3.694  -1.895 1.000 23.999 0 237 TYR   A CD2 1 ? 
ATOM   1842 C CE1 . TYR   A 1 237 ? 17.693  -2.519  -3.117 1.000 24.231 0 237 TYR   A CE1 1 ? 
ATOM   1843 C CE2 . TYR   A 1 237 ? 15.928  -4.145  -3.139 1.000 25.656 0 237 TYR   A CE2 1 ? 
ATOM   1844 C CZ  . TYR   A 1 237 ? 17.019  -3.546  -3.752 1.000 24.112 0 237 TYR   A CZ  1 ? 
ATOM   1845 O OH  . TYR   A 1 237 ? 17.463  -3.977  -4.959 1.000 23.018 0 237 TYR   A OH  1 ? 
ATOM   1846 N N   . ASN   A 1 238 ? 13.722  0.745   1.362  1.000 15.713 0 238 ASN   A N   1 ? 
ATOM   1847 C CA  . ASN   A 1 238 ? 13.045  1.267   2.539  1.000 16.002 0 238 ASN   A CA  1 ? 
ATOM   1848 C C   . ASN   A 1 238 ? 13.876  0.995   3.780  1.000 16.083 0 238 ASN   A C   1 ? 
ATOM   1849 O O   . ASN   A 1 238 ? 13.320  0.650   4.816  1.000 17.133 0 238 ASN   A O   1 ? 
ATOM   1850 C CB  . ASN   A 1 238 ? 11.640  0.695   2.779  1.000 17.588 0 238 ASN   A CB  1 ? 
ATOM   1851 C CG  . ASN   A 1 238 ? 10.732  0.976   1.607  1.000 18.423 0 238 ASN   A CG  1 ? 
ATOM   1852 O OD1 . ASN   A 1 238 ? 10.857  2.007   0.973  1.000 19.930 0 238 ASN   A OD1 1 ? 
ATOM   1853 N ND2 . ASN   A 1 238 ? 9.954   -0.003  1.187  1.000 18.845 0 238 ASN   A ND2 1 ? 
ATOM   1854 N N   . TYR   A 1 239 ? 15.186  1.214   3.676  1.000 15.372 0 239 TYR   A N   1 ? 
ATOM   1855 C CA  . TYR   A 1 239 ? 16.074  1.157   4.819  1.000 15.445 0 239 TYR   A CA  1 ? 
ATOM   1856 C C   . TYR   A 1 239 ? 16.326  2.581   5.264  1.000 17.482 0 239 TYR   A C   1 ? 
ATOM   1857 O O   . TYR   A 1 239 ? 16.420  3.454   4.411  1.000 17.501 0 239 TYR   A O   1 ? 
ATOM   1858 C CB  . TYR   A 1 239 ? 17.379  0.452   4.456  1.000 14.875 0 239 TYR   A CB  1 ? 
ATOM   1859 C CG  . TYR   A 1 239 ? 17.350  -1.056  4.682  1.000 15.232 0 239 TYR   A CG  1 ? 
ATOM   1860 C CD1 . TYR   A 1 239 ? 16.358  -1.855  4.130  1.000 13.553 0 239 TYR   A CD1 1 ? 
ATOM   1861 C CD2 . TYR   A 1 239 ? 18.333  -1.669  5.467  1.000 15.583 0 239 TYR   A CD2 1 ? 
ATOM   1862 C CE1 . TYR   A 1 239 ? 16.337  -3.226  4.349  1.000 14.773 0 239 TYR   A CE1 1 ? 
ATOM   1863 C CE2 . TYR   A 1 239 ? 18.308  -3.030  5.712  1.000 14.527 0 239 TYR   A CE2 1 ? 
ATOM   1864 C CZ  . TYR   A 1 239 ? 17.329  -3.807  5.130  1.000 14.510 0 239 TYR   A CZ  1 ? 
ATOM   1865 O OH  . TYR   A 1 239 ? 17.350  -5.129  5.402  1.000 15.396 0 239 TYR   A OH  1 ? 
ATOM   1866 N N   . GLU   A 1 240 ? 16.449  2.780   6.584  1.000 18.919 0 240 GLU   A N   1 ? 
ATOM   1867 C CA  . GLU   A 1 240 ? 16.918  4.037   7.138  1.000 20.837 0 240 GLU   A CA  1 ? 
ATOM   1868 C C   . GLU   A 1 240 ? 18.330  4.346   6.647  1.000 20.248 0 240 GLU   A C   1 ? 
ATOM   1869 O O   . GLU   A 1 240 ? 19.149  3.431   6.437  1.000 19.329 0 240 GLU   A O   1 ? 
ATOM   1870 C CB  . GLU   A 1 240 ? 16.922  4.043   8.666  1.000 21.454 0 240 GLU   A CB  1 ? 
ATOM   1871 C CG  . GLU   A 1 240 ? 15.527  4.123   9.279  1.000 24.735 0 240 GLU   A CG  1 ? 
ATOM   1872 C CD  . GLU   A 1 240 ? 14.803  5.448   9.111  1.000 27.391 0 240 GLU   A CD  1 ? 
ATOM   1873 O OE1 . GLU   A 1 240 ? 15.268  6.436   9.681  1.000 33.156 0 240 GLU   A OE1 1 ? 
ATOM   1874 O OE2 . GLU   A 1 240 ? 13.789  5.482   8.400  1.000 24.625 0 240 GLU   A OE2 1 ? 
ATOM   1875 N N   . PRO   A 1 241 ? 18.625  5.647   6.421  1.000 19.754 0 241 PRO   A N   1 ? 
ATOM   1876 C CA  . PRO   A 1 241 ? 19.981  6.088   6.126  1.000 22.091 0 241 PRO   A CA  1 ? 
ATOM   1877 C C   . PRO   A 1 241 ? 20.905  5.663   7.268  1.000 20.480 0 241 PRO   A C   1 ? 
ATOM   1878 O O   . PRO   A 1 241 ? 20.557  5.758   8.447  1.000 19.186 0 241 PRO   A O   1 ? 
ATOM   1879 C CB  . PRO   A 1 241 ? 19.892  7.626   5.998  1.000 23.498 0 241 PRO   A CB  1 ? 
ATOM   1880 C CG  . PRO   A 1 241 ? 18.422  7.874   5.694  1.000 24.802 0 241 PRO   A CG  1 ? 
ATOM   1881 C CD  . PRO   A 1 241 ? 17.668  6.762   6.401  1.000 21.239 0 241 PRO   A CD  1 ? 
ATOM   1882 N N   . LEU   A 1 242 ? 22.079  5.165   6.884  1.000 18.099 0 242 LEU   A N   1 ? 
ATOM   1883 C CA  . LEU   A 1 242 ? 23.139  4.907   7.839  1.000 17.168 0 242 LEU   A CA  1 ? 
ATOM   1884 C C   . LEU   A 1 242 ? 24.032  6.149   7.901  1.000 17.249 0 242 LEU   A C   1 ? 
ATOM   1885 O O   . LEU   A 1 242 ? 24.472  6.641   6.871  1.000 17.558 0 242 LEU   A O   1 ? 
ATOM   1886 C CB  . LEU   A 1 242 ? 23.885  3.657   7.383  1.000 15.437 0 242 LEU   A CB  1 ? 
ATOM   1887 C CG  . LEU   A 1 242 ? 24.845  3.059   8.398  1.000 14.912 0 242 LEU   A CG  1 ? 
ATOM   1888 C CD1 . LEU   A 1 242 ? 24.089  2.309   9.461  1.000 15.310 0 242 LEU   A CD1 1 ? 
ATOM   1889 C CD2 . LEU   A 1 242 ? 25.863  2.154   7.724  1.000 15.979 0 242 LEU   A CD2 1 ? 
ATOM   1890 N N   . THR   A 1 243 ? 24.196  6.696   9.111  1.000 17.442 0 243 THR   A N   1 ? 
ATOM   1891 C CA  . THR   A 1 243 ? 24.979  7.893   9.363  1.000 19.709 0 243 THR   A CA  1 ? 
ATOM   1892 C C   . THR   A 1 243 ? 26.357  7.497   9.880  1.000 19.348 0 243 THR   A C   1 ? 
ATOM   1893 O O   . THR   A 1 243 ? 26.595  6.339   10.253 1.000 18.894 0 243 THR   A O   1 ? 
ATOM   1894 C CB  . THR   A 1 243 ? 24.349  8.789   10.439 1.000 20.311 0 243 THR   A CB  1 ? 
ATOM   1895 O OG1 . THR   A 1 243 ? 24.517  8.156   11.718 1.000 19.506 0 243 THR   A OG1 1 ? 
ATOM   1896 C CG2 . THR   A 1 243 ? 22.882  9.102   10.177 1.000 22.294 0 243 THR   A CG2 1 ? 
ATOM   1897 N N   . GLN   A 1 244 ? 27.231  8.498   9.951  1.000 19.146 0 244 GLN   A N   1 ? 
ATOM   1898 C CA  . GLN   A 1 244 ? 28.581  8.308   10.463 1.000 19.163 0 244 GLN   A CA  1 ? 
ATOM   1899 C C   . GLN   A 1 244 ? 28.535  7.871   11.930 1.000 15.578 0 244 GLN   A C   1 ? 
ATOM   1900 O O   . GLN   A 1 244 ? 29.337  7.044   12.315 1.000 14.493 0 244 GLN   A O   1 ? 
ATOM   1901 C CB  . GLN   A 1 244 ? 29.446  9.558   10.244 1.000 19.651 0 244 GLN   A CB  1 ? 
ATOM   1902 C CG  . GLN   A 1 244 ? 30.927  9.325   10.597 1.000 20.501 0 244 GLN   A CG  1 ? 
ATOM   1903 C CD  . GLN   A 1 244 ? 31.620  8.226   9.807  1.000 21.879 0 244 GLN   A CD  1 ? 
ATOM   1904 O OE1 . GLN   A 1 244 ? 31.561  8.159   8.589  1.000 24.748 0 244 GLN   A OE1 1 ? 
ATOM   1905 N NE2 . GLN   A 1 244 ? 32.273  7.300   10.483 1.000 23.731 0 244 GLN   A NE2 1 ? 
ATOM   1906 N N   . ASP   A 1 245 ? 27.620  8.434   12.729 1.000 14.269 0 245 ASP   A N   1 ? 
ATOM   1907 C CA  . ASP   A 1 245 ? 27.396  8.041   14.105 1.000 15.547 0 245 ASP   A CA  1 ? 
ATOM   1908 C C   . ASP   A 1 245 ? 27.087  6.542   14.215 1.000 15.317 0 245 ASP   A C   1 ? 
ATOM   1909 O O   . ASP   A 1 245 ? 27.628  5.909   15.097 1.000 15.305 0 245 ASP   A O   1 ? 
ATOM   1910 C CB  . ASP   A 1 245 ? 26.242  8.824   14.739 1.000 17.939 0 245 ASP   A CB  1 ? 
ATOM   1911 C CG  . ASP   A 1 245 ? 26.586  10.236  15.226 1.000 20.947 0 245 ASP   A CG  1 ? 
ATOM   1912 O OD1 . ASP   A 1 245 ? 27.722  10.678  15.023 1.000 22.301 0 245 ASP   A OD1 1 ? 
ATOM   1913 O OD2 . ASP   A 1 245 ? 25.714  10.876  15.827 1.000 23.449 0 245 ASP   A OD2 1 ? 
ATOM   1914 N N   . HIS   A 1 246 ? 26.188  6.000   13.370 1.000 15.095 0 246 HIS   A N   1 ? 
ATOM   1915 C CA  . HIS   A 1 246 ? 25.915  4.565   13.302 1.000 16.123 0 246 HIS   A CA  1 ? 
ATOM   1916 C C   . HIS   A 1 246 ? 27.195  3.771   13.001 1.000 16.228 0 246 HIS   A C   1 ? 
ATOM   1917 O O   . HIS   A 1 246 ? 27.463  2.740   13.618 1.000 15.193 0 246 HIS   A O   1 ? 
ATOM   1918 C CB  . HIS   A 1 246 ? 24.818  4.267   12.261 1.000 16.411 0 246 HIS   A CB  1 ? 
ATOM   1919 C CG  . HIS   A 1 246 ? 23.461  4.873   12.527 1.000 17.586 0 246 HIS   A CG  1 ? 
ATOM   1920 N ND1 . HIS   A 1 246 ? 22.934  5.008   13.801 1.000 18.740 0 246 HIS   A ND1 1 ? 
ATOM   1921 C CD2 . HIS   A 1 246 ? 22.510  5.362   11.702 1.000 17.764 0 246 HIS   A CD2 1 ? 
ATOM   1922 C CE1 . HIS   A 1 246 ? 21.733  5.575   13.741 1.000 16.494 0 246 HIS   A CE1 1 ? 
ATOM   1923 N NE2 . HIS   A 1 246 ? 21.455  5.799   12.483 1.000 17.998 0 246 HIS   A NE2 1 ? 
ATOM   1924 N N   . VAL   A 1 247 ? 27.991  4.235   12.028 1.000 16.735 0 247 VAL   A N   1 ? 
ATOM   1925 C CA  . VAL   A 1 247 ? 29.239  3.565   11.675 1.000 17.939 0 247 VAL   A CA  1 ? 
ATOM   1926 C C   . VAL   A 1 247 ? 30.125  3.502   12.920 1.000 19.554 0 247 VAL   A C   1 ? 
ATOM   1927 O O   . VAL   A 1 247 ? 30.655  2.450   13.249 1.000 19.107 0 247 VAL   A O   1 ? 
ATOM   1928 C CB  . VAL   A 1 247 ? 29.957  4.253   10.494 1.000 17.823 0 247 VAL   A CB  1 ? 
ATOM   1929 C CG1 . VAL   A 1 247 ? 31.395  3.744   10.293 1.000 19.397 0 247 VAL   A CG1 1 ? 
ATOM   1930 C CG2 . VAL   A 1 247 ? 29.163  4.103   9.207  1.000 17.818 0 247 VAL   A CG2 1 ? 
ATOM   1931 N N   . ASP   A 1 248 ? 30.233  4.629   13.629 1.000 19.665 0 248 ASP   A N   1 ? 
ATOM   1932 C CA  . ASP   A 1 248 ? 31.087  4.735   14.801 1.000 19.876 0 248 ASP   A CA  1 ? 
ATOM   1933 C C   . ASP   A 1 248 ? 30.551  3.864   15.940 1.000 19.665 0 248 ASP   A C   1 ? 
ATOM   1934 O O   . ASP   A 1 248 ? 31.344  3.289   16.686 1.000 18.013 0 248 ASP   A O   1 ? 
ATOM   1935 C CB  . ASP   A 1 248 ? 31.224  6.201   15.228 1.000 21.527 0 248 ASP   A CB  1 ? 
ATOM   1936 C CG  . ASP   A 1 248 ? 31.948  7.114   14.240 1.000 22.780 0 248 ASP   A CG  1 ? 
ATOM   1937 O OD1 . ASP   A 1 248 ? 32.715  6.626   13.372 1.000 25.603 0 248 ASP   A OD1 1 ? 
ATOM   1938 O OD2 . ASP   A 1 248 ? 31.730  8.313   14.337 1.000 28.125 0 248 ASP   A OD2 1 ? 
ATOM   1939 N N   . ILE   A 1 249 ? 29.216  3.763   16.082 1.000 17.937 0 249 ILE   A N   1 ? 
ATOM   1940 C CA  . ILE   A 1 249 ? 28.606  2.959   17.141 1.000 17.858 0 249 ILE   A CA  1 ? 
ATOM   1941 C C   . ILE   A 1 249 ? 28.866  1.467   16.898 1.000 16.142 0 249 ILE   A C   1 ? 
ATOM   1942 O O   . ILE   A 1 249 ? 29.052  0.729   17.859 1.000 14.725 0 249 ILE   A O   1 ? 
ATOM   1943 C CB  . ILE   A 1 249 ? 27.094  3.267   17.287 1.000 20.909 0 249 ILE   A CB  1 ? 
ATOM   1944 C CG1 . ILE   A 1 249 ? 26.828  4.637   17.922 1.000 22.204 0 249 ILE   A CG1 1 ? 
ATOM   1945 C CG2 . ILE   A 1 249 ? 26.362  2.193   18.078 1.000 20.917 0 249 ILE   A CG2 1 ? 
ATOM   1946 C CD1 . ILE   A 1 249 ? 25.441  5.183   17.579 1.000 21.930 0 249 ILE   A CD1 1 ? 
ATOM   1947 N N   . LEU   A 1 250 ? 28.914  1.009   15.633 1.000 14.304 0 250 LEU   A N   1 ? 
ATOM   1948 C CA  . LEU   A 1 250 ? 29.206  -0.398  15.337 1.000 13.643 0 250 LEU   A CA  1 ? 
ATOM   1949 C C   . LEU   A 1 250 ? 30.692  -0.755  15.528 1.000 15.187 0 250 LEU   A C   1 ? 
ATOM   1950 O O   . LEU   A 1 250 ? 31.088  -1.911  15.319 1.000 15.427 0 250 LEU   A O   1 ? 
ATOM   1951 C CB  . LEU   A 1 250 ? 28.785  -0.707  13.901 1.000 12.565 0 250 LEU   A CB  1 ? 
ATOM   1952 C CG  . LEU   A 1 250 ? 27.281  -0.758  13.624 1.000 12.713 0 250 LEU   A CG  1 ? 
ATOM   1953 C CD1 . LEU   A 1 250 ? 26.991  -0.539  12.148 1.000 12.412 0 250 LEU   A CD1 1 ? 
ATOM   1954 C CD2 . LEU   A 1 250 ? 26.694  -2.090  14.053 1.000 13.668 0 250 LEU   A CD2 1 ? 
ATOM   1955 N N   . GLY   A 1 251 ? 31.553  0.203   15.894 1.000 15.895 0 251 GLY   A N   1 ? 
ATOM   1956 C CA  . GLY   A 1 251 ? 32.986  -0.073  15.924 1.000 16.599 0 251 GLY   A CA  1 ? 
ATOM   1957 C C   . GLY   A 1 251 ? 33.374  -1.230  16.853 1.000 16.510 0 251 GLY   A C   1 ? 
ATOM   1958 O O   . GLY   A 1 251 ? 34.147  -2.098  16.471 1.000 16.315 0 251 GLY   A O   1 ? 
ATOM   1959 N N   . PRO   A 1 252 ? 32.945  -1.263  18.130 1.000 17.780 0 252 PRO   A N   1 ? 
ATOM   1960 C CA  . PRO   A 1 252 ? 33.245  -2.397  19.016 1.000 20.129 0 252 PRO   A CA  1 ? 
ATOM   1961 C C   . PRO   A 1 252 ? 32.912  -3.754  18.422 1.000 19.685 0 252 PRO   A C   1 ? 
ATOM   1962 O O   . PRO   A 1 252 ? 33.690  -4.691  18.545 1.000 20.182 0 252 PRO   A O   1 ? 
ATOM   1963 C CB  . PRO   A 1 252 ? 32.398  -2.124  20.266 1.000 19.464 0 252 PRO   A CB  1 ? 
ATOM   1964 C CG  . PRO   A 1 252 ? 32.433  -0.622  20.327 1.000 19.344 0 252 PRO   A CG  1 ? 
ATOM   1965 C CD  . PRO   A 1 252 ? 32.352  -0.152  18.870 1.000 19.531 0 252 PRO   A CD  1 ? 
ATOM   1966 N N   . LEU   A 1 253 ? 31.792  -3.846  17.709 1.000 20.143 0 253 LEU   A N   1 ? 
ATOM   1967 C CA  . LEU   A 1 253 ? 31.437  -5.111  17.087 1.000 19.377 0 253 LEU   A CA  1 ? 
ATOM   1968 C C   . LEU   A 1 253 ? 32.397  -5.430  15.946 1.000 19.631 0 253 LEU   A C   1 ? 
ATOM   1969 O O   . LEU   A 1 253 ? 32.806  -6.574  15.740 1.000 21.406 0 253 LEU   A O   1 ? 
ATOM   1970 C CB  . LEU   A 1 253 ? 29.984  -5.067  16.609 1.000 17.855 0 253 LEU   A CB  1 ? 
ATOM   1971 C CG  . LEU   A 1 253 ? 28.949  -5.366  17.679 1.000 16.789 0 253 LEU   A CG  1 ? 
ATOM   1972 C CD1 . LEU   A 1 253 ? 27.559  -5.175  17.094 1.000 17.230 0 253 LEU   A CD1 1 ? 
ATOM   1973 C CD2 . LEU   A 1 253 ? 29.119  -6.796  18.215 1.000 16.925 0 253 LEU   A CD2 1 ? 
ATOM   1974 N N   . SER   A 1 254 ? 32.773  -4.407  15.200 1.000 19.021 0 254 SER   A N   1 ? 
ATOM   1975 C CA  . SER   A 1 254 ? 33.750  -4.612  14.146 1.000 20.696 0 254 SER   A CA  1 ? 
ATOM   1976 C C   . SER   A 1 254 ? 35.114  -5.079  14.699 1.000 21.567 0 254 SER   A C   1 ? 
ATOM   1977 O O   . SER   A 1 254 ? 35.724  -5.973  14.124 1.000 23.571 0 254 SER   A O   1 ? 
ATOM   1978 C CB  . SER   A 1 254 ? 33.827  -3.374  13.324 1.000 19.661 0 254 SER   A CB  1 ? 
ATOM   1979 O OG  . SER   A 1 254 ? 35.087  -3.234  12.774 1.000 23.297 0 254 SER   A OG  1 ? 
ATOM   1980 N N   . ALA   A 1 255 ? 35.597  -4.515  15.813 1.000 20.683 0 255 ALA   A N   1 ? 
ATOM   1981 C CA  . ALA   A 1 255 ? 36.877  -4.921  16.402 1.000 23.089 0 255 ALA   A CA  1 ? 
ATOM   1982 C C   . ALA   A 1 255 ? 36.847  -6.386  16.845 1.000 25.020 0 255 ALA   A C   1 ? 
ATOM   1983 O O   . ALA   A 1 255 ? 37.804  -7.127  16.654 1.000 26.376 0 255 ALA   A O   1 ? 
ATOM   1984 C CB  . ALA   A 1 255 ? 37.233  -4.044  17.588 1.000 21.985 0 255 ALA   A CB  1 ? 
ATOM   1985 N N   . GLN   A 1 256 ? 35.730  -6.796  17.445 1.000 27.211 0 256 GLN   A N   1 ? 
ATOM   1986 C CA  . GLN   A 1 256 ? 35.540  -8.153  17.919 1.000 27.849 0 256 GLN   A CA  1 ? 
ATOM   1987 C C   . GLN   A 1 256 ? 35.611  -9.202  16.811 1.000 26.168 0 256 GLN   A C   1 ? 
ATOM   1988 O O   . GLN   A 1 256 ? 35.993  -10.328 17.106 1.000 25.403 0 256 GLN   A O   1 ? 
ATOM   1989 C CB  . GLN   A 1 256 ? 34.173  -8.266  18.587 1.000 33.118 0 256 GLN   A CB  1 ? 
ATOM   1990 C CG  . GLN   A 1 256 ? 33.838  -9.664  19.084 1.000 35.449 0 256 GLN   A CG  1 ? 
ATOM   1991 C CD  . GLN   A 1 256 ? 32.736  -9.634  20.118 1.000 40.798 0 256 GLN   A CD  1 ? 
ATOM   1992 O OE1 . GLN   A 1 256 ? 32.310  -8.567  20.566 1.000 42.400 0 256 GLN   A OE1 1 ? 
ATOM   1993 N NE2 . GLN   A 1 256 ? 32.263  -10.812 20.501 1.000 39.499 0 256 GLN   A NE2 1 ? 
ATOM   1994 N N   . THR   A 1 257 ? 35.187  -8.878  15.575 1.000 24.416 0 257 THR   A N   1 ? 
ATOM   1995 C CA  . THR   A 1 257 ? 35.101  -9.863  14.501 1.000 21.192 0 257 THR   A CA  1 ? 
ATOM   1996 C C   . THR   A 1 257 ? 36.211  -9.669  13.462 1.000 22.707 0 257 THR   A C   1 ? 
ATOM   1997 O O   . THR   A 1 257 ? 36.440  -10.534 12.612 1.000 23.458 0 257 THR   A O   1 ? 
ATOM   1998 C CB  . THR   A 1 257 ? 33.741  -9.767  13.799 1.000 20.486 0 257 THR   A CB  1 ? 
ATOM   1999 O OG1 . THR   A 1 257 ? 33.527  -8.411  13.387 1.000 19.253 0 257 THR   A OG1 1 ? 
ATOM   2000 C CG2 . THR   A 1 257 ? 32.581  -10.178 14.678 1.000 20.067 0 257 THR   A CG2 1 ? 
ATOM   2001 N N   . GLY   A 1 258 ? 36.850  -8.494  13.457 1.000 20.840 0 258 GLY   A N   1 ? 
ATOM   2002 C CA  . GLY   A 1 258 ? 37.847  -8.188  12.435 1.000 20.742 0 258 GLY   A CA  1 ? 
ATOM   2003 C C   . GLY   A 1 258 ? 37.238  -7.789  11.088 1.000 21.201 0 258 GLY   A C   1 ? 
ATOM   2004 O O   . GLY   A 1 258 ? 37.963  -7.688  10.109 1.000 20.826 0 258 GLY   A O   1 ? 
ATOM   2005 N N   . ILE   A 1 259 ? 35.915  -7.559  11.034 1.000 19.413 0 259 ILE   A N   1 ? 
ATOM   2006 C CA  . ILE   A 1 259 ? 35.258  -7.143  9.805  1.000 17.711 0 259 ILE   A CA  1 ? 
ATOM   2007 C C   . ILE   A 1 259 ? 34.898  -5.673  9.921  1.000 16.145 0 259 ILE   A C   1 ? 
ATOM   2008 O O   . ILE   A 1 259 ? 34.127  -5.289  10.805 1.000 16.338 0 259 ILE   A O   1 ? 
ATOM   2009 C CB  . ILE   A 1 259 ? 34.009  -8.000  9.521  1.000 18.528 0 259 ILE   A CB  1 ? 
ATOM   2010 C CG1 . ILE   A 1 259 ? 34.356  -9.490  9.504  1.000 19.855 0 259 ILE   A CG1 1 ? 
ATOM   2011 C CG2 . ILE   A 1 259 ? 33.355  -7.555  8.214  1.000 18.058 0 259 ILE   A CG2 1 ? 
ATOM   2012 C CD1 . ILE   A 1 259 ? 33.177  -10.344 9.752  1.000 21.821 0 259 ILE   A CD1 1 ? 
ATOM   2013 N N   . ALA   A 1 260 ? 35.443  -4.867  9.003  1.000 14.808 0 260 ALA   A N   1 ? 
ATOM   2014 C CA  . ALA   A 1 260 ? 35.232  -3.439  9.054  1.000 15.210 0 260 ALA   A CA  1 ? 
ATOM   2015 C C   . ALA   A 1 260 ? 33.767  -3.140  8.728  1.000 13.938 0 260 ALA   A C   1 ? 
ATOM   2016 O O   . ALA   A 1 260 ? 33.111  -3.858  7.983  1.000 13.353 0 260 ALA   A O   1 ? 
ATOM   2017 C CB  . ALA   A 1 260 ? 36.217  -2.730  8.147  1.000 15.601 0 260 ALA   A CB  1 ? 
ATOM   2018 N N   . VAL   A 1 261 ? 33.235  -2.083  9.324  1.000 13.361 0 261 VAL   A N   1 ? 
ATOM   2019 C CA  . VAL   A 1 261 ? 31.818  -1.790  9.196  1.000 15.003 0 261 VAL   A CA  1 ? 
ATOM   2020 C C   . VAL   A 1 261 ? 31.389  -1.665  7.720  1.000 15.164 0 261 VAL   A C   1 ? 
ATOM   2021 O O   . VAL   A 1 261 ? 30.311  -2.117  7.340  1.000 14.102 0 261 VAL   A O   1 ? 
ATOM   2022 C CB  . VAL   A 1 261 ? 31.457  -0.526  9.991  1.000 14.738 0 261 VAL   A CB  1 ? 
ATOM   2023 C CG1 . VAL   A 1 261 ? 30.010  -0.109  9.729  1.000 14.712 0 261 VAL   A CG1 1 ? 
ATOM   2024 C CG2 . VAL   A 1 261 ? 31.706  -0.701  11.466 1.000 13.877 0 261 VAL   A CG2 1 ? 
ATOM   2025 N N   . LEU   A 1 262 ? 32.223  -1.027  6.895  1.000 16.039 0 262 LEU   A N   1 ? 
ATOM   2026 C CA  . LEU   A 1 262 ? 31.896  -0.735  5.508  1.000 17.434 0 262 LEU   A CA  1 ? 
ATOM   2027 C C   . LEU   A 1 262 ? 32.074  -1.976  4.631  1.000 16.772 0 262 LEU   A C   1 ? 
ATOM   2028 O O   . LEU   A 1 262 ? 31.415  -2.089  3.601  1.000 14.342 0 262 LEU   A O   1 ? 
ATOM   2029 C CB  . LEU   A 1 262 ? 32.747  0.450   5.040  1.000 18.457 0 262 LEU   A CB  1 ? 
ATOM   2030 C CG  . LEU   A 1 262 ? 32.358  1.782   5.687  1.000 20.902 0 262 LEU   A CG  1 ? 
ATOM   2031 C CD1 . LEU   A 1 262 ? 33.324  2.895   5.281  1.000 24.031 0 262 LEU   A CD1 1 ? 
ATOM   2032 C CD2 . LEU   A 1 262 ? 30.931  2.184   5.333  1.000 20.121 0 262 LEU   A CD2 1 ? 
ATOM   2033 N N   . ASP   A 1 263 ? 32.894  -2.935  5.091  1.000 16.668 0 263 ASP   A N   1 ? 
ATOM   2034 C CA  . ASP   A 1 263 ? 32.876  -4.283  4.531  1.000 18.068 0 263 ASP   A CA  1 ? 
ATOM   2035 C C   . ASP   A 1 263 ? 31.554  -4.981  4.880  1.000 15.802 0 263 ASP   A C   1 ? 
ATOM   2036 O O   . ASP   A 1 263 ? 30.940  -5.571  4.005  1.000 14.541 0 263 ASP   A O   1 ? 
ATOM   2037 C CB  . ASP   A 1 263 ? 34.099  -5.108  4.939  1.000 19.414 0 263 ASP   A CB  1 ? 
ATOM   2038 C CG  . ASP   A 1 263 ? 35.405  -4.494  4.442  1.000 26.035 0 263 ASP   A CG  1 ? 
ATOM   2039 O OD1 . ASP   A 1 263 ? 35.377  -3.327  3.953  1.000 29.167 0 263 ASP   A OD1 1 ? 
ATOM   2040 O OD2 . ASP   A 1 263 ? 36.458  -5.173  4.539  1.000 30.658 0 263 ASP   A OD2 1 ? 
ATOM   2041 N N   . MET   A 1 264 ? 31.090  -4.897  6.128  1.000 15.275 0 264 MET   A N   1 ? 
ATOM   2042 C CA  . MET   A 1 264 ? 29.784  -5.457  6.447  1.000 16.520 0 264 MET   A CA  1 ? 
ATOM   2043 C C   . MET   A 1 264 ? 28.699  -4.776  5.597  1.000 15.640 0 264 MET   A C   1 ? 
ATOM   2044 O O   . MET   A 1 264 ? 27.761  -5.418  5.166  1.000 15.553 0 264 MET   A O   1 ? 
ATOM   2045 C CB  . MET   A 1 264 ? 29.427  -5.346  7.929  1.000 16.047 0 264 MET   A CB  1 ? 
ATOM   2046 C CG  . MET   A 1 264 ? 28.239  -6.256  8.342  1.000 16.481 0 264 MET   A CG  1 ? 
ATOM   2047 S SD  . MET   A 1 264 ? 28.618  -8.062  8.073  1.000 17.241 0 264 MET   A SD  1 ? 
ATOM   2048 C CE  . MET   A 1 264 ? 29.433  -8.470  9.618  1.000 16.903 0 264 MET   A CE  1 ? 
ATOM   2049 N N   . CYS   A 1 265 ? 28.811  -3.464  5.364  1.000 16.837 0 265 CYS   A N   1 ? 
ATOM   2050 C CA  . CYS   A 1 265 ? 27.803  -2.719  4.608  1.000 15.053 0 265 CYS   A CA  1 ? 
ATOM   2051 C C   . CYS   A 1 265 ? 27.763  -3.223  3.163  1.000 13.999 0 265 CYS   A C   1 ? 
ATOM   2052 O O   . CYS   A 1 265 ? 26.692  -3.351  2.595  1.000 12.301 0 265 CYS   A O   1 ? 
ATOM   2053 C CB  . CYS   A 1 265 ? 28.069  -1.222  4.613  1.000 15.769 0 265 CYS   A CB  1 ? 
ATOM   2054 S SG  . CYS   A 1 265 ? 27.761  -0.419  6.205  1.000 20.411 0 265 CYS   A SG  1 ? 
ATOM   2055 N N   . ALA   A 1 266 ? 28.927  -3.569  2.604  1.000 13.995 0 266 ALA   A N   1 ? 
ATOM   2056 C CA  . ALA   A 1 266 ? 28.998  -4.111  1.251  1.000 14.648 0 266 ALA   A CA  1 ? 
ATOM   2057 C C   . ALA   A 1 266 ? 28.349  -5.500  1.165  1.000 15.183 0 266 ALA   A C   1 ? 
ATOM   2058 O O   . ALA   A 1 266 ? 27.676  -5.817  0.196  1.000 14.299 0 266 ALA   A O   1 ? 
ATOM   2059 C CB  . ALA   A 1 266 ? 30.440  -4.132  0.809  1.000 13.943 0 266 ALA   A CB  1 ? 
ATOM   2060 N N   . SER   A 1 267 ? 28.497  -6.324  2.208  1.000 15.428 0 267 SER   A N   1 ? 
ATOM   2061 C CA  . SER   A 1 267 ? 27.732  -7.555  2.316  1.000 16.327 0 267 SER   A CA  1 ? 
ATOM   2062 C C   . SER   A 1 267 ? 26.219  -7.307  2.402  1.000 15.236 0 267 SER   A C   1 ? 
ATOM   2063 O O   . SER   A 1 267 ? 25.457  -7.933  1.671  1.000 13.248 0 267 SER   A O   1 ? 
ATOM   2064 C CB  . SER   A 1 267 ? 28.267  -8.394  3.459  1.000 18.368 0 267 SER   A CB  1 ? 
ATOM   2065 O OG  . SER   A 1 267 ? 29.603  -8.790  3.145  1.000 20.408 0 267 SER   A OG  1 ? 
ATOM   2066 N N   . LEU   A 1 268 ? 25.759  -6.372  3.251  1.000 14.203 0 268 LEU   A N   1 ? 
ATOM   2067 C CA  . LEU   A 1 268 ? 24.336  -6.061  3.308  1.000 13.477 0 268 LEU   A CA  1 ? 
ATOM   2068 C C   . LEU   A 1 268 ? 23.836  -5.548  1.950  1.000 15.255 0 268 LEU   A C   1 ? 
ATOM   2069 O O   . LEU   A 1 268 ? 22.735  -5.897  1.513  1.000 13.197 0 268 LEU   A O   1 ? 
ATOM   2070 C CB  . LEU   A 1 268 ? 24.071  -5.043  4.418  1.000 12.643 0 268 LEU   A CB  1 ? 
ATOM   2071 C CG  . LEU   A 1 268 ? 22.641  -4.530  4.573  1.000 12.871 0 268 LEU   A CG  1 ? 
ATOM   2072 C CD1 . LEU   A 1 268 ? 21.611  -5.660  4.651  1.000 12.729 0 268 LEU   A CD1 1 ? 
ATOM   2073 C CD2 . LEU   A 1 268 ? 22.515  -3.653  5.808  1.000 13.110 0 268 LEU   A CD2 1 ? 
ATOM   2074 N N   . LYS   A 1 269 ? 24.639  -4.716  1.273  1.000 16.727 0 269 LYS   A N   1 ? 
ATOM   2075 C CA  . LYS   A 1 269 ? 24.202  -4.133  0.010  1.000 20.228 0 269 LYS   A CA  1 ? 
ATOM   2076 C C   . LYS   A 1 269 ? 23.905  -5.260  -0.992 1.000 20.576 0 269 LYS   A C   1 ? 
ATOM   2077 O O   . LYS   A 1 269 ? 22.904  -5.210  -1.707 1.000 20.515 0 269 LYS   A O   1 ? 
ATOM   2078 C CB  . LYS   A 1 269 ? 25.239  -3.124  -0.496 1.000 21.865 0 269 LYS   A CB  1 ? 
ATOM   2079 C CG  . LYS   A 1 269 ? 25.058  -2.684  -1.951 1.000 26.820 0 269 LYS   A CG  1 ? 
ATOM   2080 C CD  . LYS   A 1 269 ? 25.825  -1.396  -2.329 1.000 27.913 0 269 LYS   A CD  1 ? 
ATOM   2081 C CE  . LYS   A 1 269 ? 27.307  -1.568  -2.511 1.000 29.994 0 269 LYS   A CE  1 ? 
ATOM   2082 N NZ  . LYS   A 1 269 ? 27.993  -0.266  -2.736 1.000 30.457 0 269 LYS   A NZ  1 ? 
ATOM   2083 N N   . GLU   A 1 270 ? 24.768  -6.283  -1.008 1.000 20.787 0 270 GLU   A N   1 ? 
ATOM   2084 C CA  . GLU   A 1 270 ? 24.607  -7.436  -1.882 1.000 23.264 0 270 GLU   A CA  1 ? 
ATOM   2085 C C   . GLU   A 1 270 ? 23.353  -8.225  -1.505 1.000 20.458 0 270 GLU   A C   1 ? 
ATOM   2086 O O   . GLU   A 1 270 ? 22.636  -8.717  -2.382 1.000 20.963 0 270 GLU   A O   1 ? 
ATOM   2087 C CB  . GLU   A 1 270 ? 25.886  -8.288  -1.872 1.000 26.408 0 270 GLU   A CB  1 ? 
ATOM   2088 C CG  . GLU   A 1 270 ? 25.745  -9.655  -2.547 1.000 30.329 0 270 GLU   A CG  1 ? 
ATOM   2089 C CD  . GLU   A 1 270 ? 27.014  -10.309 -3.104 1.000 37.095 0 270 GLU   A CD  1 ? 
ATOM   2090 O OE1 . GLU   A 1 270 ? 28.017  -10.440 -2.367 1.000 38.106 0 270 GLU   A OE1 1 ? 
ATOM   2091 O OE2 . GLU   A 1 270 ? 27.001  -10.703 -4.302 1.000 43.221 0 270 GLU   A OE2 1 ? 
ATOM   2092 N N   . LEU   A 1 271 ? 23.084  -8.370  -0.202 1.000 17.726 0 271 LEU   A N   1 ? 
ATOM   2093 C CA  . LEU   A 1 271 ? 21.898  -9.098  0.238  1.000 15.933 0 271 LEU   A CA  1 ? 
ATOM   2094 C C   . LEU   A 1 271 ? 20.620  -8.389  -0.185 1.000 16.815 0 271 LEU   A C   1 ? 
ATOM   2095 O O   . LEU   A 1 271 ? 19.621  -9.059  -0.477 1.000 16.065 0 271 LEU   A O   1 ? 
ATOM   2096 C CB  . LEU   A 1 271 ? 21.920  -9.276  1.749  1.000 15.460 0 271 LEU   A CB  1 ? 
ATOM   2097 C CG  . LEU   A 1 271 ? 22.989  -10.246 2.268  1.000 15.317 0 271 LEU   A CG  1 ? 
ATOM   2098 C CD1 . LEU   A 1 271 ? 23.142  -10.118 3.751  1.000 15.151 0 271 LEU   A CD1 1 ? 
ATOM   2099 C CD2 . LEU   A 1 271 ? 22.665  -11.691 1.896  1.000 16.561 0 271 LEU   A CD2 1 ? 
ATOM   2100 N N   . LEU   A 1 272 ? 20.640  -7.047  -0.200 1.000 15.403 0 272 LEU   A N   1 ? 
ATOM   2101 C CA  . LEU   A 1 272 ? 19.441  -6.318  -0.572 1.000 17.224 0 272 LEU   A CA  1 ? 
ATOM   2102 C C   . LEU   A 1 272 ? 19.231  -6.435  -2.076 1.000 18.545 0 272 LEU   A C   1 ? 
ATOM   2103 O O   . LEU   A 1 272 ? 18.104  -6.577  -2.536 1.000 18.949 0 272 LEU   A O   1 ? 
ATOM   2104 C CB  . LEU   A 1 272 ? 19.546  -4.850  -0.157 1.000 16.136 0 272 LEU   A CB  1 ? 
ATOM   2105 C CG  . LEU   A 1 272 ? 19.490  -4.578  1.338  1.000 17.666 0 272 LEU   A CG  1 ? 
ATOM   2106 C CD1 . LEU   A 1 272 ? 19.615  -3.089  1.613  1.000 17.403 0 272 LEU   A CD1 1 ? 
ATOM   2107 C CD2 . LEU   A 1 272 ? 18.196  -5.110  1.938  1.000 20.035 0 272 LEU   A CD2 1 ? 
ATOM   2108 N N   . GLN   A 1 273 ? 20.331  -6.379  -2.835 1.000 21.347 0 273 GLN   A N   1 ? 
ATOM   2109 C CA  . GLN   A 1 273 ? 20.253  -6.336  -4.289 1.000 22.754 0 273 GLN   A CA  1 ? 
ATOM   2110 C C   . GLN   A 1 273 ? 19.954  -7.725  -4.852 1.000 23.709 0 273 GLN   A C   1 ? 
ATOM   2111 O O   . GLN   A 1 273 ? 19.311  -7.839  -5.886 1.000 22.477 0 273 GLN   A O   1 ? 
ATOM   2112 C CB  . GLN   A 1 273 ? 21.548  -5.780  -4.887 1.000 23.445 0 273 GLN   A CB  1 ? 
ATOM   2113 C CG  . GLN   A 1 273 ? 21.677  -4.271  -4.736 1.000 24.379 0 273 GLN   A CG  1 ? 
ATOM   2114 C CD  . GLN   A 1 273 ? 22.965  -3.713  -5.300 1.000 28.075 0 273 GLN   A CD  1 ? 
ATOM   2115 O OE1 . GLN   A 1 273 ? 22.993  -2.596  -5.808 1.000 32.427 0 273 GLN   A OE1 1 ? 
ATOM   2116 N NE2 . GLN   A 1 273 ? 24.056  -4.453  -5.169 1.000 26.467 0 273 GLN   A NE2 1 ? 
ATOM   2117 N N   . ASN   A 1 274 ? 20.451  -8.775  -4.198 1.000 23.323 0 274 ASN   A N   1 ? 
ATOM   2118 C CA  . ASN   A 1 274 ? 20.354  -10.111 -4.762 1.000 27.265 0 274 ASN   A CA  1 ? 
ATOM   2119 C C   . ASN   A 1 274 ? 19.353  -10.961 -3.984 1.000 26.745 0 274 ASN   A C   1 ? 
ATOM   2120 O O   . ASN   A 1 274 ? 18.912  -11.987 -4.474 1.000 27.021 0 274 ASN   A O   1 ? 
ATOM   2121 C CB  . ASN   A 1 274 ? 21.702  -10.827 -4.808 1.000 28.669 0 274 ASN   A CB  1 ? 
ATOM   2122 C CG  . ASN   A 1 274 ? 22.759  -10.155 -5.665 1.000 35.520 0 274 ASN   A CG  1 ? 
ATOM   2123 O OD1 . ASN   A 1 274 ? 23.924  -10.535 -5.592 1.000 45.214 0 274 ASN   A OD1 1 ? 
ATOM   2124 N ND2 . ASN   A 1 274 ? 22.407  -9.165  -6.470 1.000 33.726 0 274 ASN   A ND2 1 ? 
ATOM   2125 N N   . GLY   A 1 275 ? 18.960  -10.528 -2.787 1.000 27.326 0 275 GLY   A N   1 ? 
ATOM   2126 C CA  . GLY   A 1 275 ? 18.113  -11.352 -1.936 1.000 27.048 0 275 GLY   A CA  1 ? 
ATOM   2127 C C   . GLY   A 1 275 ? 18.950  -12.449 -1.296 1.000 27.885 0 275 GLY   A C   1 ? 
ATOM   2128 O O   . GLY   A 1 275 ? 20.153  -12.561 -1.543 1.000 28.945 0 275 GLY   A O   1 ? 
ATOM   2129 N N   . MET   A 1 276 ? 18.307  -13.250 -0.469 1.000 31.971 0 276 MET   A N   1 ? 
ATOM   2130 C CA  . MET   A 1 276 ? 19.013  -14.267 0.287  1.000 41.822 0 276 MET   A CA  1 ? 
ATOM   2131 C C   . MET   A 1 276 ? 19.088  -15.591 -0.483 1.000 43.823 0 276 MET   A C   1 ? 
ATOM   2132 O O   . MET   A 1 276 ? 19.868  -16.466 -0.120 1.000 43.732 0 276 MET   A O   1 ? 
ATOM   2133 C CB  . MET   A 1 276 ? 18.369  -14.425 1.670  1.000 45.533 0 276 MET   A CB  1 ? 
ATOM   2134 C CG  . MET   A 1 276 ? 19.221  -13.778 2.758  1.000 46.910 0 276 MET   A CG  1 ? 
ATOM   2135 S SD  . MET   A 1 276 ? 18.481  -13.846 4.393  1.000 52.051 0 276 MET   A SD  1 ? 
ATOM   2136 C CE  . MET   A 1 276 ? 17.449  -12.389 4.275  1.000 52.149 0 276 MET   A CE  1 ? 
ATOM   2137 N N   . ASN   A 1 277 ? 18.331  -15.722 -1.581 1.000 51.298 0 277 ASN   A N   1 ? 
ATOM   2138 C CA  . ASN   A 1 277 ? 18.519  -16.835 -2.498 1.000 51.281 0 277 ASN   A CA  1 ? 
ATOM   2139 C C   . ASN   A 1 277 ? 18.094  -18.119 -1.777 1.000 48.767 0 277 ASN   A C   1 ? 
ATOM   2140 O O   . ASN   A 1 277 ? 18.765  -19.147 -1.884 1.000 46.239 0 277 ASN   A O   1 ? 
ATOM   2141 C CB  . ASN   A 1 277 ? 19.980  -16.855 -2.991 1.000 59.793 0 277 ASN   A CB  1 ? 
ATOM   2142 C CG  . ASN   A 1 277 ? 20.154  -17.195 -4.461 1.000 63.411 0 277 ASN   A CG  1 ? 
ATOM   2143 O OD1 . ASN   A 1 277 ? 19.735  -16.435 -5.335 1.000 60.535 0 277 ASN   A OD1 1 ? 
ATOM   2144 N ND2 . ASN   A 1 277 ? 20.807  -18.312 -4.748 1.000 58.322 0 277 ASN   A ND2 1 ? 
ATOM   2145 N N   . GLY   A 1 278 ? 17.008  -18.032 -0.988 1.000 44.182 0 278 GLY   A N   1 ? 
ATOM   2146 C CA  . GLY   A 1 278 ? 16.502  -19.162 -0.216 1.000 40.440 0 278 GLY   A CA  1 ? 
ATOM   2147 C C   . GLY   A 1 278 ? 17.327  -19.493 1.035  1.000 36.551 0 278 GLY   A C   1 ? 
ATOM   2148 O O   . GLY   A 1 278 ? 16.981  -20.398 1.782  1.000 32.388 0 278 GLY   A O   1 ? 
ATOM   2149 N N   . ARG   A 1 279 ? 18.386  -18.732 1.322  1.000 34.858 0 279 ARG   A N   1 ? 
ATOM   2150 C CA  . ARG   A 1 279 ? 19.306  -19.112 2.390  1.000 32.844 0 279 ARG   A CA  1 ? 
ATOM   2151 C C   . ARG   A 1 279 ? 18.919  -18.370 3.671  1.000 25.746 0 279 ARG   A C   1 ? 
ATOM   2152 O O   . ARG   A 1 279 ? 18.091  -17.468 3.603  1.000 30.665 0 279 ARG   A O   1 ? 
ATOM   2153 C CB  . ARG   A 1 279 ? 20.743  -18.849 1.933  1.000 34.876 0 279 ARG   A CB  1 ? 
ATOM   2154 C CG  . ARG   A 1 279 ? 21.643  -20.058 2.125  1.000 40.793 0 279 ARG   A CG  1 ? 
ATOM   2155 C CD  . ARG   A 1 279 ? 22.930  -19.778 2.856  1.000 43.280 0 279 ARG   A CD  1 ? 
ATOM   2156 N NE  . ARG   A 1 279 ? 24.097  -19.965 2.013  1.000 44.931 0 279 ARG   A NE  1 ? 
ATOM   2157 C CZ  . ARG   A 1 279 ? 25.194  -20.618 2.394  1.000 41.322 0 279 ARG   A CZ  1 ? 
ATOM   2158 N NH1 . ARG   A 1 279 ? 25.315  -21.070 3.634  1.000 37.229 0 279 ARG   A NH1 1 ? 
ATOM   2159 N NH2 . ARG   A 1 279 ? 26.169  -20.813 1.525  1.000 40.864 0 279 ARG   A NH2 1 ? 
ATOM   2160 N N   . THR   A 1 280 ? 19.445  -18.795 4.830  1.000 22.693 0 280 THR   A N   1 ? 
ATOM   2161 C CA  . THR   A 1 280 ? 19.071  -18.225 6.124  1.000 22.601 0 280 THR   A CA  1 ? 
ATOM   2162 C C   . THR   A 1 280 ? 20.299  -17.709 6.880  1.000 19.488 0 280 THR   A C   1 ? 
ATOM   2163 O O   . THR   A 1 280 ? 21.430  -18.084 6.589  1.000 18.485 0 280 THR   A O   1 ? 
ATOM   2164 C CB  . THR   A 1 280 ? 18.304  -19.198 7.042  1.000 23.025 0 280 THR   A CB  1 ? 
ATOM   2165 O OG1 . THR   A 1 280 ? 19.162  -20.293 7.354  1.000 24.965 0 280 THR   A OG1 1 ? 
ATOM   2166 C CG2 . THR   A 1 280 ? 17.005  -19.716 6.460  1.000 21.981 0 280 THR   A CG2 1 ? 
ATOM   2167 N N   . ILE   A 1 281 ? 20.046  -16.795 7.822  1.000 17.524 0 281 ILE   A N   1 ? 
ATOM   2168 C CA  . ILE   A 1 281 ? 21.069  -16.217 8.681  1.000 17.641 0 281 ILE   A CA  1 ? 
ATOM   2169 C C   . ILE   A 1 281 ? 20.540  -16.277 10.105 1.000 17.772 0 281 ILE   A C   1 ? 
ATOM   2170 O O   . ILE   A 1 281 ? 19.486  -15.699 10.392 1.000 16.389 0 281 ILE   A O   1 ? 
ATOM   2171 C CB  . ILE   A 1 281 ? 21.420  -14.767 8.274  1.000 16.979 0 281 ILE   A CB  1 ? 
ATOM   2172 C CG1 . ILE   A 1 281 ? 21.995  -14.691 6.861  1.000 17.125 0 281 ILE   A CG1 1 ? 
ATOM   2173 C CG2 . ILE   A 1 281 ? 22.355  -14.119 9.292  1.000 16.804 0 281 ILE   A CG2 1 ? 
ATOM   2174 C CD1 . ILE   A 1 281 ? 22.109  -13.278 6.307  1.000 18.573 0 281 ILE   A CD1 1 ? 
ATOM   2175 N N   . LEU   A 1 282 ? 21.300  -16.967 10.975 1.000 18.372 0 282 LEU   A N   1 ? 
ATOM   2176 C CA  . LEU   A 1 282 ? 20.906  -17.237 12.345 1.000 17.563 0 282 LEU   A CA  1 ? 
ATOM   2177 C C   . LEU   A 1 282 ? 19.494  -17.814 12.351 1.000 18.984 0 282 LEU   A C   1 ? 
ATOM   2178 O O   . LEU   A 1 282 ? 18.675  -17.409 13.165 1.000 20.293 0 282 LEU   A O   1 ? 
ATOM   2179 C CB  . LEU   A 1 282 ? 20.928  -15.950 13.159 1.000 18.793 0 282 LEU   A CB  1 ? 
ATOM   2180 C CG  . LEU   A 1 282 ? 22.288  -15.396 13.564 1.000 19.382 0 282 LEU   A CG  1 ? 
ATOM   2181 C CD1 . LEU   A 1 282 ? 22.103  -13.999 14.106 1.000 19.529 0 282 LEU   A CD1 1 ? 
ATOM   2182 C CD2 . LEU   A 1 282 ? 22.968  -16.282 14.593 1.000 18.677 0 282 LEU   A CD2 1 ? 
ATOM   2183 N N   . GLY   A 1 283 ? 19.213  -18.712 11.406 1.000 20.201 0 283 GLY   A N   1 ? 
ATOM   2184 C CA  . GLY   A 1 283 ? 17.942  -19.407 11.329 1.000 22.650 0 283 GLY   A CA  1 ? 
ATOM   2185 C C   . GLY   A 1 283 ? 16.798  -18.560 10.763 1.000 25.432 0 283 GLY   A C   1 ? 
ATOM   2186 O O   . GLY   A 1 283 ? 15.674  -19.039 10.722 1.000 27.895 0 283 GLY   A O   1 ? 
ATOM   2187 N N   . SER   A 1 284 ? 17.067  -17.331 10.297 1.000 24.976 0 284 SER   A N   1 ? 
ATOM   2188 C CA  . SER   A 1 284 ? 16.008  -16.463 9.799  1.000 23.368 0 284 SER   A CA  1 ? 
ATOM   2189 C C   . SER   A 1 284 ? 16.144  -16.253 8.293  1.000 22.185 0 284 SER   A C   1 ? 
ATOM   2190 O O   . SER   A 1 284 ? 17.243  -16.087 7.772  1.000 20.382 0 284 SER   A O   1 ? 
ATOM   2191 C CB  . SER   A 1 284 ? 15.989  -15.147 10.541 1.000 25.086 0 284 SER   A CB  1 ? 
ATOM   2192 O OG  . SER   A 1 284 ? 15.163  -14.222 9.844  1.000 29.208 0 284 SER   A OG  1 ? 
ATOM   2193 N N   . ALA   A 1 285 ? 15.005  -16.264 7.589  1.000 21.173 0 285 ALA   A N   1 ? 
ATOM   2194 C CA  . ALA   A 1 285 ? 14.981  -16.080 6.152  1.000 21.213 0 285 ALA   A CA  1 ? 
ATOM   2195 C C   . ALA   A 1 285 ? 14.807  -14.607 5.806  1.000 21.411 0 285 ALA   A C   1 ? 
ATOM   2196 O O   . ALA   A 1 285 ? 14.852  -14.215 4.645  1.000 22.831 0 285 ALA   A O   1 ? 
ATOM   2197 C CB  . ALA   A 1 285 ? 13.882  -16.923 5.543  1.000 22.765 0 285 ALA   A CB  1 ? 
ATOM   2198 N N   . LEU   A 1 286 ? 14.679  -13.756 6.816  1.000 22.241 0 286 LEU   A N   1 ? 
ATOM   2199 C CA  . LEU   A 1 286 ? 14.777  -12.337 6.550  1.000 23.545 0 286 LEU   A CA  1 ? 
ATOM   2200 C C   . LEU   A 1 286 ? 15.751  -11.680 7.522  1.000 21.455 0 286 LEU   A C   1 ? 
ATOM   2201 O O   . LEU   A 1 286 ? 16.135  -12.251 8.538  1.000 22.358 0 286 LEU   A O   1 ? 
ATOM   2202 C CB  . LEU   A 1 286 ? 13.384  -11.697 6.588  1.000 27.969 0 286 LEU   A CB  1 ? 
ATOM   2203 C CG  . LEU   A 1 286 ? 12.352  -12.278 7.538  1.000 33.901 0 286 LEU   A CG  1 ? 
ATOM   2204 C CD1 . LEU   A 1 286 ? 12.567  -11.769 8.956  1.000 39.540 0 286 LEU   A CD1 1 ? 
ATOM   2205 C CD2 . LEU   A 1 286 ? 10.935  -11.948 7.053  1.000 37.344 0 286 LEU   A CD2 1 ? 
ATOM   2206 N N   . LEU   A 1 287 ? 16.114  -10.448 7.194  1.000 18.256 0 287 LEU   A N   1 ? 
ATOM   2207 C CA  . LEU   A 1 287 ? 17.057  -9.683  7.979  1.000 19.570 0 287 LEU   A CA  1 ? 
ATOM   2208 C C   . LEU   A 1 287 ? 16.331  -9.075  9.178  1.000 19.999 0 287 LEU   A C   1 ? 
ATOM   2209 O O   . LEU   A 1 287 ? 15.287  -8.465  9.035  1.000 22.332 0 287 LEU   A O   1 ? 
ATOM   2210 C CB  . LEU   A 1 287 ? 17.642  -8.596  7.073  1.000 20.693 0 287 LEU   A CB  1 ? 
ATOM   2211 C CG  . LEU   A 1 287 ? 18.221  -9.088  5.747  1.000 22.038 0 287 LEU   A CG  1 ? 
ATOM   2212 C CD1 . LEU   A 1 287 ? 18.606  -7.917  4.858  1.000 23.661 0 287 LEU   A CD1 1 ? 
ATOM   2213 C CD2 . LEU   A 1 287 ? 19.413  -10.010 5.978  1.000 22.031 0 287 LEU   A CD2 1 ? 
ATOM   2214 N N   . GLU   A 1 288 ? 16.924  -9.237  10.350 1.000 18.954 0 288 GLU   A N   1 ? 
ATOM   2215 C CA  . GLU   A 1 288 ? 16.333  -8.871  11.620 1.000 18.932 0 288 GLU   A CA  1 ? 
ATOM   2216 C C   . GLU   A 1 288 ? 16.836  -7.481  12.020 1.000 15.947 0 288 GLU   A C   1 ? 
ATOM   2217 O O   . GLU   A 1 288 ? 18.042  -7.228  11.979 1.000 14.205 0 288 GLU   A O   1 ? 
ATOM   2218 C CB  . GLU   A 1 288 ? 16.750  -9.930  12.646 1.000 20.928 0 288 GLU   A CB  1 ? 
ATOM   2219 C CG  . GLU   A 1 288 ? 16.304  -9.614  14.054 1.000 26.579 0 288 GLU   A CG  1 ? 
ATOM   2220 C CD  . GLU   A 1 288 ? 14.797  -9.509  14.238 1.000 29.927 0 288 GLU   A CD  1 ? 
ATOM   2221 O OE1 . GLU   A 1 288 ? 14.080  -10.425 13.741 1.000 30.186 0 288 GLU   A OE1 1 ? 
ATOM   2222 O OE2 . GLU   A 1 288 ? 14.346  -8.511  14.862 1.000 29.325 0 288 GLU   A OE2 1 ? 
ATOM   2223 N N   . ASP   A 1 289 ? 15.916  -6.610  12.452 1.000 15.388 0 289 ASP   A N   1 ? 
ATOM   2224 C CA  . ASP   A 1 289 ? 16.269  -5.217  12.757 1.000 16.386 0 289 ASP   A CA  1 ? 
ATOM   2225 C C   . ASP   A 1 289 ? 15.832  -4.789  14.163 1.000 15.175 0 289 ASP   A C   1 ? 
ATOM   2226 O O   . ASP   A 1 289 ? 15.858  -3.595  14.458 1.000 16.553 0 289 ASP   A O   1 ? 
ATOM   2227 C CB  . ASP   A 1 289 ? 15.760  -4.261  11.662 1.000 16.673 0 289 ASP   A CB  1 ? 
ATOM   2228 C CG  . ASP   A 1 289 ? 14.289  -3.886  11.751 1.000 16.877 0 289 ASP   A CG  1 ? 
ATOM   2229 O OD1 . ASP   A 1 289 ? 13.552  -4.630  12.385 1.000 17.182 0 289 ASP   A OD1 1 ? 
ATOM   2230 O OD2 . ASP   A 1 289 ? 13.903  -2.819  11.211 1.000 15.866 0 289 ASP   A OD2 1 ? 
ATOM   2231 N N   . GLU   A 1 290 ? 15.544  -5.739  15.074 1.000 14.487 0 290 GLU   A N   1 ? 
ATOM   2232 C CA  . GLU   A 1 290 ? 15.199  -5.383  16.446 1.000 15.601 0 290 GLU   A CA  1 ? 
ATOM   2233 C C   . GLU   A 1 290 ? 16.235  -5.828  17.486 1.000 15.177 0 290 GLU   A C   1 ? 
ATOM   2234 O O   . GLU   A 1 290 ? 15.888  -6.002  18.648 1.000 15.057 0 290 GLU   A O   1 ? 
ATOM   2235 C CB  . GLU   A 1 290 ? 13.798  -5.901  16.782 1.000 16.235 0 290 GLU   A CB  1 ? 
ATOM   2236 C CG  . GLU   A 1 290 ? 12.730  -5.239  15.920 1.000 17.662 0 290 GLU   A CG  1 ? 
ATOM   2237 C CD  . GLU   A 1 290 ? 11.323  -5.136  16.514 1.000 20.249 0 290 GLU   A CD  1 ? 
ATOM   2238 O OE1 . GLU   A 1 290 ? 11.066  -5.783  17.539 1.000 23.034 0 290 GLU   A OE1 1 ? 
ATOM   2239 O OE2 . GLU   A 1 290 ? 10.466  -4.413  15.922 1.000 21.144 0 290 GLU   A OE2 1 ? 
ATOM   2240 N N   . PHE   A 1 291 ? 17.504  -5.974  17.092 1.000 14.864 0 291 PHE   A N   1 ? 
ATOM   2241 C CA  . PHE   A 1 291 ? 18.619  -5.968  18.038 1.000 14.530 0 291 PHE   A CA  1 ? 
ATOM   2242 C C   . PHE   A 1 291 ? 19.478  -4.727  17.806 1.000 14.182 0 291 PHE   A C   1 ? 
ATOM   2243 O O   . PHE   A 1 291 ? 20.043  -4.550  16.722 1.000 14.260 0 291 PHE   A O   1 ? 
ATOM   2244 C CB  . PHE   A 1 291 ? 19.527  -7.187  17.838 1.000 15.657 0 291 PHE   A CB  1 ? 
ATOM   2245 C CG  . PHE   A 1 291 ? 18.858  -8.507  18.081 1.000 16.754 0 291 PHE   A CG  1 ? 
ATOM   2246 C CD1 . PHE   A 1 291 ? 18.137  -9.138  17.077 1.000 18.395 0 291 PHE   A CD1 1 ? 
ATOM   2247 C CD2 . PHE   A 1 291 ? 18.949  -9.119  19.329 1.000 18.901 0 291 PHE   A CD2 1 ? 
ATOM   2248 C CE1 . PHE   A 1 291 ? 17.495  -10.355 17.310 1.000 19.299 0 291 PHE   A CE1 1 ? 
ATOM   2249 C CE2 . PHE   A 1 291 ? 18.323  -10.347 19.553 1.000 19.537 0 291 PHE   A CE2 1 ? 
ATOM   2250 C CZ  . PHE   A 1 291 ? 17.577  -10.946 18.556 1.000 18.107 0 291 PHE   A CZ  1 ? 
ATOM   2251 N N   . THR   A 1 292 ? 19.644  -3.898  18.836 1.000 14.245 0 292 THR   A N   1 ? 
ATOM   2252 C CA  . THR   A 1 292 ? 20.602  -2.809  18.754 1.000 13.936 0 292 THR   A CA  1 ? 
ATOM   2253 C C   . THR   A 1 292 ? 22.020  -3.368  18.845 1.000 14.061 0 292 THR   A C   1 ? 
ATOM   2254 O O   . THR   A 1 292 ? 22.202  -4.498  19.294 1.000 13.129 0 292 THR   A O   1 ? 
ATOM   2255 C CB  . THR   A 1 292 ? 20.378  -1.772  19.855 1.000 13.481 0 292 THR   A CB  1 ? 
ATOM   2256 O OG1 . THR   A 1 292 ? 20.771  -2.398  21.079 1.000 13.483 0 292 THR   A OG1 1 ? 
ATOM   2257 C CG2 . THR   A 1 292 ? 18.962  -1.258  19.897 1.000 13.446 0 292 THR   A CG2 1 ? 
ATOM   2258 N N   . PRO   A 1 293 ? 23.065  -2.583  18.481 1.000 14.521 0 293 PRO   A N   1 ? 
ATOM   2259 C CA  . PRO   A 1 293 ? 24.454  -2.987  18.721 1.000 15.957 0 293 PRO   A CA  1 ? 
ATOM   2260 C C   . PRO   A 1 293 ? 24.762  -3.355  20.174 1.000 17.951 0 293 PRO   A C   1 ? 
ATOM   2261 O O   . PRO   A 1 293 ? 25.511  -4.315  20.420 1.000 14.800 0 293 PRO   A O   1 ? 
ATOM   2262 C CB  . PRO   A 1 293 ? 25.288  -1.775  18.249 1.000 15.449 0 293 PRO   A CB  1 ? 
ATOM   2263 C CG  . PRO   A 1 293 ? 24.383  -1.132  17.181 1.000 14.885 0 293 PRO   A CG  1 ? 
ATOM   2264 C CD  . PRO   A 1 293 ? 22.977  -1.307  17.735 1.000 15.495 0 293 PRO   A CD  1 ? 
ATOM   2265 N N   . PHE   A 1 294 ? 24.156  -2.617  21.120 1.000 20.138 0 294 PHE   A N   1 ? 
ATOM   2266 C CA  . PHE   A 1 294 ? 24.313  -2.924  22.530 1.000 23.909 0 294 PHE   A CA  1 ? 
ATOM   2267 C C   . PHE   A 1 294 ? 23.630  -4.253  22.898 1.000 21.038 0 294 PHE   A C   1 ? 
ATOM   2268 O O   . PHE   A 1 294 ? 24.224  -5.022  23.631 1.000 17.349 0 294 PHE   A O   1 ? 
ATOM   2269 C CB  . PHE   A 1 294 ? 23.884  -1.770  23.447 1.000 30.461 0 294 PHE   A CB  1 ? 
ATOM   2270 C CG  . PHE   A 1 294 ? 24.130  -2.101  24.902 1.000 40.756 0 294 PHE   A CG  1 ? 
ATOM   2271 C CD1 . PHE   A 1 294 ? 25.419  -2.094  25.426 1.000 43.620 0 294 PHE   A CD1 1 ? 
ATOM   2272 C CD2 . PHE   A 1 294 ? 23.097  -2.568  25.712 1.000 47.728 0 294 PHE   A CD2 1 ? 
ATOM   2273 C CE1 . PHE   A 1 294 ? 25.650  -2.473  26.744 1.000 49.878 0 294 PHE   A CE1 1 ? 
ATOM   2274 C CE2 . PHE   A 1 294 ? 23.334  -2.954  27.028 1.000 48.026 0 294 PHE   A CE2 1 ? 
ATOM   2275 C CZ  . PHE   A 1 294 ? 24.610  -2.901  27.544 1.000 47.740 0 294 PHE   A CZ  1 ? 
ATOM   2276 N N   . ASP   A 1 295 ? 22.422  -4.554  22.383 1.000 20.819 0 295 ASP   A N   1 ? 
ATOM   2277 C CA  . ASP   A 1 295 ? 21.759  -5.834  22.645 1.000 19.845 0 295 ASP   A CA  1 ? 
ATOM   2278 C C   . ASP   A 1 295 ? 22.626  -7.014  22.233 1.000 18.088 0 295 ASP   A C   1 ? 
ATOM   2279 O O   . ASP   A 1 295 ? 22.650  -8.032  22.939 1.000 18.813 0 295 ASP   A O   1 ? 
ATOM   2280 C CB  . ASP   A 1 295 ? 20.444  -6.004  21.880 1.000 22.628 0 295 ASP   A CB  1 ? 
ATOM   2281 C CG  . ASP   A 1 295 ? 19.416  -4.977  22.296 1.000 23.938 0 295 ASP   A CG  1 ? 
ATOM   2282 O OD1 . ASP   A 1 295 ? 19.609  -4.444  23.397 1.000 23.113 0 295 ASP   A OD1 1 ? 
ATOM   2283 O OD2 . ASP   A 1 295 ? 18.503  -4.659  21.481 1.000 22.609 0 295 ASP   A OD2 1 ? 
ATOM   2284 N N   . VAL   A 1 296 ? 23.355  -6.852  21.121 1.000 15.593 0 296 VAL   A N   1 ? 
ATOM   2285 C CA  . VAL   A 1 296 ? 24.195  -7.901  20.570 1.000 15.638 0 296 VAL   A CA  1 ? 
ATOM   2286 C C   . VAL   A 1 296 ? 25.402  -8.131  21.484 1.000 18.183 0 296 VAL   A C   1 ? 
ATOM   2287 O O   . VAL   A 1 296 ? 25.726  -9.279  21.794 1.000 16.379 0 296 VAL   A O   1 ? 
ATOM   2288 C CB  . VAL   A 1 296 ? 24.624  -7.564  19.132 1.000 14.506 0 296 VAL   A CB  1 ? 
ATOM   2289 C CG1 . VAL   A 1 296 ? 25.728  -8.467  18.610 1.000 14.268 0 296 VAL   A CG1 1 ? 
ATOM   2290 C CG2 . VAL   A 1 296 ? 23.442  -7.591  18.186 1.000 14.565 0 296 VAL   A CG2 1 ? 
ATOM   2291 N N   . VAL   A 1 297 ? 26.064  -7.032  21.884 1.000 20.228 0 297 VAL   A N   1 ? 
ATOM   2292 C CA  . VAL   A 1 297 ? 27.186  -7.067  22.818 1.000 22.768 0 297 VAL   A CA  1 ? 
ATOM   2293 C C   . VAL   A 1 297 ? 26.748  -7.714  24.136 1.000 24.797 0 297 VAL   A C   1 ? 
ATOM   2294 O O   . VAL   A 1 297 ? 27.433  -8.603  24.634 1.000 25.829 0 297 VAL   A O   1 ? 
ATOM   2295 C CB  . VAL   A 1 297 ? 27.764  -5.656  23.041 1.000 25.041 0 297 VAL   A CB  1 ? 
ATOM   2296 C CG1 . VAL   A 1 297 ? 28.660  -5.565  24.278 1.000 27.174 0 297 VAL   A CG1 1 ? 
ATOM   2297 C CG2 . VAL   A 1 297 ? 28.511  -5.147  21.824 1.000 24.523 0 297 VAL   A CG2 1 ? 
ATOM   2298 N N   . ARG   A 1 298 ? 25.616  -7.247  24.683 1.000 25.362 0 298 ARG   A N   1 ? 
ATOM   2299 C CA  . ARG   A 1 298 ? 25.043  -7.749  25.919 1.000 29.100 0 298 ARG   A CA  1 ? 
ATOM   2300 C C   . ARG   A 1 298 ? 24.876  -9.263  25.833 1.000 28.177 0 298 ARG   A C   1 ? 
ATOM   2301 O O   . ARG   A 1 298 ? 25.245  -9.989  26.755 1.000 28.775 0 298 ARG   A O   1 ? 
ATOM   2302 C CB  . ARG   A 1 298 ? 23.716  -7.023  26.200 1.000 35.600 0 298 ARG   A CB  1 ? 
ATOM   2303 C CG  . ARG   A 1 298 ? 22.702  -7.781  27.057 1.000 44.724 0 298 ARG   A CG  1 ? 
ATOM   2304 C CD  . ARG   A 1 298 ? 21.417  -6.998  27.359 1.000 50.160 0 298 ARG   A CD  1 ? 
ATOM   2305 N NE  . ARG   A 1 298 ? 20.430  -7.823  28.060 1.000 51.980 0 298 ARG   A NE  1 ? 
ATOM   2306 C CZ  . ARG   A 1 298 ? 19.209  -8.154  27.619 1.000 57.131 0 298 ARG   A CZ  1 ? 
ATOM   2307 N NH1 . ARG   A 1 298 ? 18.507  -9.064  28.280 1.000 49.719 0 298 ARG   A NH1 1 ? 
ATOM   2308 N NH2 . ARG   A 1 298 ? 18.704  -7.625  26.511 1.000 55.920 0 298 ARG   A NH2 1 ? 
ATOM   2309 N N   . GLN   A 1 299 ? 24.287  -9.737  24.732 1.000 26.575 0 299 GLN   A N   1 ? 
ATOM   2310 C CA  . GLN   A 1 299 ? 23.946  -11.142 24.632 1.000 25.313 0 299 GLN   A CA  1 ? 
ATOM   2311 C C   . GLN   A 1 299 ? 25.212  -11.950 24.390 1.000 26.217 0 299 GLN   A C   1 ? 
ATOM   2312 O O   . GLN   A 1 299 ? 25.353  -12.997 25.008 1.000 25.138 0 299 GLN   A O   1 ? 
ATOM   2313 C CB  . GLN   A 1 299 ? 22.910  -11.437 23.551 1.000 23.021 0 299 GLN   A CB  1 ? 
ATOM   2314 C CG  . GLN   A 1 299 ? 22.397  -12.860 23.662 1.000 23.036 0 299 GLN   A CG  1 ? 
ATOM   2315 C CD  . GLN   A 1 299 ? 21.238  -13.192 22.752 1.000 21.427 0 299 GLN   A CD  1 ? 
ATOM   2316 O OE1 . GLN   A 1 299 ? 21.064  -14.343 22.368 1.000 20.285 0 299 GLN   A OE1 1 ? 
ATOM   2317 N NE2 . GLN   A 1 299 ? 20.467  -12.194 22.354 1.000 20.244 0 299 GLN   A NE2 1 ? 
ATOM   2318 N N   . CYS   A 1 300 ? 26.138  -11.438 23.556 1.000 25.002 0 300 CYS   A N   1 ? 
ATOM   2319 C CA  . CYS   A 1 300 ? 27.322  -12.192 23.162 1.000 27.300 0 300 CYS   A CA  1 ? 
ATOM   2320 C C   . CYS   A 1 300 ? 28.440  -12.079 24.209 1.000 33.677 0 300 CYS   A C   1 ? 
ATOM   2321 O O   . CYS   A 1 300 ? 29.431  -12.799 24.099 1.000 35.611 0 300 CYS   A O   1 ? 
ATOM   2322 C CB  . CYS   A 1 300 ? 27.810  -11.775 21.776 1.000 25.854 0 300 CYS   A CB  1 ? 
ATOM   2323 S SG  . CYS   A 1 300 ? 26.631  -12.200 20.462 1.000 32.839 0 300 CYS   A SG  1 ? 
ATOM   2324 N N   . SER   A 1 301 ? 28.278  -11.215 25.230 1.000 36.505 0 301 SER   A N   1 ? 
ATOM   2325 C CA  . SER   A 1 301 ? 29.256  -11.092 26.308 1.000 40.843 0 301 SER   A CA  1 ? 
ATOM   2326 C C   . SER   A 1 301 ? 28.656  -11.369 27.698 1.000 42.828 0 301 SER   A C   1 ? 
ATOM   2327 O O   . SER   A 1 301 ? 29.390  -11.377 28.682 1.000 43.698 0 301 SER   A O   1 ? 
ATOM   2328 C CB  . SER   A 1 301 ? 29.921  -9.741  26.266 1.000 43.455 0 301 SER   A CB  1 ? 
ATOM   2329 O OG  . SER   A 1 301 ? 29.129  -8.782  26.953 1.000 47.669 0 301 SER   A OG  1 ? 
ATOM   2330 N N   . GLY   A 1 302 ? 27.334  -11.603 27.792 1.000 41.487 0 302 GLY   A N   1 ? 
ATOM   2331 C CA  . GLY   A 1 302 ? 26.687  -12.069 29.014 1.000 40.087 0 302 GLY   A CA  1 ? 
ATOM   2332 C C   . GLY   A 1 302 ? 26.643  -11.031 30.140 1.000 40.340 0 302 GLY   A C   1 ? 
ATOM   2333 O O   . GLY   A 1 302 ? 26.777  -11.384 31.316 1.000 31.754 0 302 GLY   A O   1 ? 
ATOM   2334 N N   . VAL   A 1 303 ? 26.413  -9.757  29.796 1.000 40.618 0 303 VAL   A N   1 ? 
ATOM   2335 C CA  . VAL   A 1 303 ? 26.267  -8.746  30.837 1.000 49.484 0 303 VAL   A CA  1 ? 
ATOM   2336 C C   . VAL   A 1 303 ? 24.978  -9.063  31.598 1.000 51.822 0 303 VAL   A C   1 ? 
ATOM   2337 O O   . VAL   A 1 303 ? 23.971  -9.473  31.004 1.000 48.384 0 303 VAL   A O   1 ? 
ATOM   2338 C CB  . VAL   A 1 303 ? 26.316  -7.276  30.344 1.000 52.130 0 303 VAL   A CB  1 ? 
ATOM   2339 C CG1 . VAL   A 1 303 ? 27.396  -7.044  29.294 1.000 51.717 0 303 VAL   A CG1 1 ? 
ATOM   2340 C CG2 . VAL   A 1 303 ? 24.973  -6.770  29.842 1.000 55.058 0 303 VAL   A CG2 1 ? 
ATOM   2341 N N   . THR   A 1 304 ? 25.049  -8.869  32.922 1.000 48.765 0 304 THR   A N   1 ? 
ATOM   2342 C CA  . THR   A 1 304 ? 24.109  -9.439  33.871 1.000 53.493 0 304 THR   A CA  1 ? 
ATOM   2343 C C   . THR   A 1 304 ? 23.527  -8.284  34.707 1.000 57.820 0 304 THR   A C   1 ? 
ATOM   2344 O O   . THR   A 1 304 ? 24.049  -7.163  34.645 1.000 41.163 0 304 THR   A O   1 ? 
ATOM   2345 C CB  . THR   A 1 304 ? 24.858  -10.591 34.568 1.000 56.708 0 304 THR   A CB  1 ? 
ATOM   2346 O OG1 . THR   A 1 304 ? 23.917  -11.575 34.991 1.000 53.252 0 304 THR   A OG1 1 ? 
ATOM   2347 C CG2 . THR   A 1 304 ? 25.743  -10.146 35.720 1.000 58.069 0 304 THR   A CG2 1 ? 
ATOM   2348 N N   . PHE   A 1 305 ? 22.431  -8.543  35.457 1.000 60.342 0 305 PHE   A N   1 ? 
ATOM   2349 C CA  . PHE   A 1 305 ? 21.693  -7.505  36.182 1.000 66.904 0 305 PHE   A CA  1 ? 
ATOM   2350 C C   . PHE   A 1 305 ? 21.346  -7.935  37.613 1.000 73.281 0 305 PHE   A C   1 ? 
ATOM   2351 O O   . PHE   A 1 305 ? 20.769  -9.003  37.830 1.000 74.657 0 305 PHE   A O   1 ? 
ATOM   2352 C CB  . PHE   A 1 305 ? 20.396  -7.153  35.442 1.000 67.075 0 305 PHE   A CB  1 ? 
ATOM   2353 C CG  . PHE   A 1 305 ? 20.615  -6.857  33.983 1.000 69.498 0 305 PHE   A CG  1 ? 
ATOM   2354 C CD1 . PHE   A 1 305 ? 21.209  -5.664  33.590 1.000 75.375 0 305 PHE   A CD1 1 ? 
ATOM   2355 C CD2 . PHE   A 1 305 ? 20.326  -7.808  33.016 1.000 68.080 0 305 PHE   A CD2 1 ? 
ATOM   2356 C CE1 . PHE   A 1 305 ? 21.463  -5.403  32.253 1.000 75.025 0 305 PHE   A CE1 1 ? 
ATOM   2357 C CE2 . PHE   A 1 305 ? 20.583  -7.549  31.678 1.000 73.207 0 305 PHE   A CE2 1 ? 
ATOM   2358 C CZ  . PHE   A 1 305 ? 21.154  -6.350  31.301 1.000 78.903 0 305 PHE   A CZ  1 ? 
ATOM   2359 N N   . GLN   A 1 306 ? 21.690  -7.080  38.586 1.000 72.064 0 306 GLN   A N   1 ? 
ATOM   2360 C CA  . GLN   A 1 306 ? 21.180  -7.199  39.944 1.000 77.538 0 306 GLN   A CA  1 ? 
ATOM   2361 C C   . GLN   A 1 306 ? 21.328  -5.854  40.660 1.000 75.583 0 306 GLN   A C   1 ? 
ATOM   2362 O O   . GLN   A 1 306 ? 20.275  -5.212  40.838 1.000 72.958 0 306 GLN   A O   1 ? 
ATOM   2363 C CB  . GLN   A 1 306 ? 21.865  -8.322  40.733 1.000 82.419 0 306 GLN   A CB  1 ? 
ATOM   2364 C CG  . GLN   A 1 306 ? 20.994  -9.566  40.914 1.000 79.295 0 306 GLN   A CG  1 ? 
ATOM   2365 C CD  . GLN   A 1 306 ? 21.337  -10.365 42.150 1.000 81.788 0 306 GLN   A CD  1 ? 
ATOM   2366 O OE1 . GLN   A 1 306 ? 21.554  -11.575 42.093 1.000 67.592 0 306 GLN   A OE1 1 ? 
ATOM   2367 N NE2 . GLN   A 1 306 ? 21.365  -9.695  43.293 1.000 82.454 0 306 GLN   A NE2 1 ? 
ATOM   2368 N N   . SER   B 1 1   ? -4.359  -7.027  19.567 1.000 27.760 0 1   SER   B N   1 ? 
ATOM   2369 C CA  . SER   B 1 1   ? -3.819  -8.055  18.652 1.000 23.815 0 1   SER   B CA  1 ? 
ATOM   2370 C C   . SER   B 1 1   ? -2.299  -7.933  18.599 1.000 20.221 0 1   SER   B C   1 ? 
ATOM   2371 O O   . SER   B 1 1   ? -1.706  -7.288  19.467 1.000 17.750 0 1   SER   B O   1 ? 
ATOM   2372 C CB  . SER   B 1 1   ? -4.467  -7.913  17.312 1.000 27.382 0 1   SER   B CB  1 ? 
ATOM   2373 O OG  . SER   B 1 1   ? -4.185  -6.652  16.764 1.000 29.480 0 1   SER   B OG  1 ? 
ATOM   2374 N N   . GLY   B 1 2   ? -1.689  -8.594  17.607 1.000 18.512 0 2   GLY   B N   1 ? 
ATOM   2375 C CA  . GLY   B 1 2   ? -0.255  -8.781  17.519 1.000 18.249 0 2   GLY   B CA  1 ? 
ATOM   2376 C C   . GLY   B 1 2   ? 0.118   -10.140 18.107 1.000 17.425 0 2   GLY   B C   1 ? 
ATOM   2377 O O   . GLY   B 1 2   ? -0.661  -10.757 18.811 1.000 18.753 0 2   GLY   B O   1 ? 
ATOM   2378 N N   . PHE   B 1 3   ? 1.293   -10.641 17.789 1.000 16.912 0 3   PHE   B N   1 ? 
ATOM   2379 C CA  . PHE   B 1 3   ? 1.634   -11.967 18.246 1.000 18.819 0 3   PHE   B CA  1 ? 
ATOM   2380 C C   . PHE   B 1 3   ? 3.137   -12.022 18.321 1.000 18.548 0 3   PHE   B C   1 ? 
ATOM   2381 O O   . PHE   B 1 3   ? 3.782   -11.732 17.339 1.000 17.209 0 3   PHE   B O   1 ? 
ATOM   2382 C CB  . PHE   B 1 3   ? 1.064   -13.059 17.333 1.000 20.174 0 3   PHE   B CB  1 ? 
ATOM   2383 C CG  . PHE   B 1 3   ? 1.062   -14.435 17.959 1.000 20.040 0 3   PHE   B CG  1 ? 
ATOM   2384 C CD1 . PHE   B 1 3   ? 0.124   -14.775 18.912 1.000 21.637 0 3   PHE   B CD1 1 ? 
ATOM   2385 C CD2 . PHE   B 1 3   ? 2.023   -15.368 17.623 1.000 21.057 0 3   PHE   B CD2 1 ? 
ATOM   2386 C CE1 . PHE   B 1 3   ? 0.140   -16.031 19.503 1.000 23.629 0 3   PHE   B CE1 1 ? 
ATOM   2387 C CE2 . PHE   B 1 3   ? 2.042   -16.620 18.209 1.000 21.285 0 3   PHE   B CE2 1 ? 
ATOM   2388 C CZ  . PHE   B 1 3   ? 1.106   -16.951 19.153 1.000 22.107 0 3   PHE   B CZ  1 ? 
ATOM   2389 N N   . ARG   B 1 4   ? 3.649   -12.330 19.509 1.000 19.202 0 4   ARG   B N   1 ? 
ATOM   2390 C CA  . ARG   B 1 4   ? 5.072   -12.284 19.782 1.000 19.931 0 4   ARG   B CA  1 ? 
ATOM   2391 C C   . ARG   B 1 4   ? 5.487   -13.584 20.465 1.000 20.912 0 4   ARG   B C   1 ? 
ATOM   2392 O O   . ARG   B 1 4   ? 4.690   -14.192 21.187 1.000 18.709 0 4   ARG   B O   1 ? 
ATOM   2393 C CB  . ARG   B 1 4   ? 5.363   -11.118 20.732 1.000 23.206 0 4   ARG   B CB  1 ? 
ATOM   2394 C CG  . ARG   B 1 4   ? 5.549   -9.780  20.047 1.000 25.082 0 4   ARG   B CG  1 ? 
ATOM   2395 C CD  . ARG   B 1 4   ? 6.937   -9.682  19.439 1.000 26.769 0 4   ARG   B CD  1 ? 
ATOM   2396 N NE  . ARG   B 1 4   ? 7.204   -8.299  19.082 1.000 31.810 0 4   ARG   B NE  1 ? 
ATOM   2397 C CZ  . ARG   B 1 4   ? 8.290   -7.883  18.446 1.000 36.338 0 4   ARG   B CZ  1 ? 
ATOM   2398 N NH1 . ARG   B 1 4   ? 8.345   -6.652  17.959 1.000 32.714 0 4   ARG   B NH1 1 ? 
ATOM   2399 N NH2 . ARG   B 1 4   ? 9.300   -8.721  18.258 1.000 37.925 0 4   ARG   B NH2 1 ? 
ATOM   2400 N N   . LYS   B 1 5   ? 6.756   -13.967 20.301 1.000 21.306 0 5   LYS   B N   1 ? 
ATOM   2401 C CA  . LYS   B 1 5   ? 7.337   -14.946 21.201 1.000 23.254 0 5   LYS   B CA  1 ? 
ATOM   2402 C C   . LYS   B 1 5   ? 7.394   -14.304 22.585 1.000 22.030 0 5   LYS   B C   1 ? 
ATOM   2403 O O   . LYS   B 1 5   ? 8.002   -13.269 22.765 1.000 22.214 0 5   LYS   B O   1 ? 
ATOM   2404 C CB  . LYS   B 1 5   ? 8.736   -15.379 20.761 1.000 27.554 0 5   LYS   B CB  1 ? 
ATOM   2405 C CG  . LYS   B 1 5   ? 9.241   -16.675 21.397 1.000 31.200 0 5   LYS   B CG  1 ? 
ATOM   2406 C CD  . LYS   B 1 5   ? 8.922   -17.939 20.619 1.000 34.257 0 5   LYS   B CD  1 ? 
ATOM   2407 C CE  . LYS   B 1 5   ? 9.417   -17.906 19.188 1.000 35.953 0 5   LYS   B CE  1 ? 
ATOM   2408 N NZ  . LYS   B 1 5   ? 10.152  -19.138 18.842 1.000 36.460 0 5   LYS   B NZ  1 ? 
ATOM   2409 N N   . MET   B 1 6   ? 6.723   -14.930 23.546 1.000 21.480 0 6   MET   B N   1 ? 
ATOM   2410 C CA  . MET   B 1 6   ? 6.473   -14.340 24.842 1.000 21.519 0 6   MET   B CA  1 ? 
ATOM   2411 C C   . MET   B 1 6   ? 6.937   -15.348 25.895 1.000 19.232 0 6   MET   B C   1 ? 
ATOM   2412 O O   . MET   B 1 6   ? 6.524   -16.501 25.871 1.000 16.379 0 6   MET   B O   1 ? 
ATOM   2413 C CB  . MET   B 1 6   ? 4.971   -14.067 24.960 1.000 22.368 0 6   MET   B CB  1 ? 
ATOM   2414 C CG  . MET   B 1 6   ? 4.582   -13.129 26.043 1.000 27.678 0 6   MET   B CG  1 ? 
ATOM   2415 S SD  . MET   B 1 6   ? 2.791   -12.758 25.986 1.000 29.918 0 6   MET   B SD  1 ? 
ATOM   2416 C CE  . MET   B 1 6   ? 2.692   -11.720 24.537 1.000 29.179 0 6   MET   B CE  1 ? 
ATOM   2417 N N   . ALA   B 1 7   ? 7.803   -14.900 26.803 1.000 16.848 0 7   ALA   B N   1 ? 
ATOM   2418 C CA  . ALA   B 1 7   ? 8.199   -15.696 27.952 1.000 17.149 0 7   ALA   B CA  1 ? 
ATOM   2419 C C   . ALA   B 1 7   ? 7.303   -15.399 29.159 1.000 17.559 0 7   ALA   B C   1 ? 
ATOM   2420 O O   . ALA   B 1 7   ? 6.596   -14.389 29.182 1.000 15.424 0 7   ALA   B O   1 ? 
ATOM   2421 C CB  . ALA   B 1 7   ? 9.652   -15.421 28.245 1.000 17.304 0 7   ALA   B CB  1 ? 
ATOM   2422 N N   . PHE   B 1 8   ? 7.290   -16.321 30.145 1.000 17.324 0 8   PHE   B N   1 ? 
ATOM   2423 C CA  . PHE   B 1 8   ? 6.565   -16.045 31.372 1.000 18.804 0 8   PHE   B CA  1 ? 
ATOM   2424 C C   . PHE   B 1 8   ? 7.303   -14.951 32.139 1.000 17.516 0 8   PHE   B C   1 ? 
ATOM   2425 O O   . PHE   B 1 8   ? 8.519   -14.870 32.082 1.000 17.553 0 8   PHE   B O   1 ? 
ATOM   2426 C CB  . PHE   B 1 8   ? 6.378   -17.290 32.248 1.000 18.894 0 8   PHE   B CB  1 ? 
ATOM   2427 C CG  . PHE   B 1 8   ? 5.343   -18.277 31.758 1.000 20.059 0 8   PHE   B CG  1 ? 
ATOM   2428 C CD1 . PHE   B 1 8   ? 3.990   -18.069 31.991 1.000 20.492 0 8   PHE   B CD1 1 ? 
ATOM   2429 C CD2 . PHE   B 1 8   ? 5.719   -19.385 31.018 1.000 18.857 0 8   PHE   B CD2 1 ? 
ATOM   2430 C CE1 . PHE   B 1 8   ? 3.043   -18.973 31.528 1.000 21.070 0 8   PHE   B CE1 1 ? 
ATOM   2431 C CE2 . PHE   B 1 8   ? 4.767   -20.269 30.538 1.000 21.224 0 8   PHE   B CE2 1 ? 
ATOM   2432 C CZ  . PHE   B 1 8   ? 3.434   -20.081 30.821 1.000 20.336 0 8   PHE   B CZ  1 ? 
ATOM   2433 N N   . PRO   B 1 9   ? 6.600   -14.132 32.944 1.000 18.739 0 9   PRO   B N   1 ? 
ATOM   2434 C CA  . PRO   B 1 9   ? 7.264   -13.206 33.871 1.000 20.029 0 9   PRO   B CA  1 ? 
ATOM   2435 C C   . PRO   B 1 9   ? 8.229   -14.010 34.739 1.000 17.997 0 9   PRO   B C   1 ? 
ATOM   2436 O O   . PRO   B 1 9   ? 7.849   -15.055 35.244 1.000 18.553 0 9   PRO   B O   1 ? 
ATOM   2437 C CB  . PRO   B 1 9   ? 6.106   -12.636 34.725 1.000 19.082 0 9   PRO   B CB  1 ? 
ATOM   2438 C CG  . PRO   B 1 9   ? 4.873   -12.857 33.856 1.000 19.919 0 9   PRO   B CG  1 ? 
ATOM   2439 C CD  . PRO   B 1 9   ? 5.137   -14.171 33.142 1.000 19.977 0 9   PRO   B CD  1 ? 
ATOM   2440 N N   . SER   B 1 10  ? 9.453   -13.522 34.923 1.000 18.057 0 10  SER   B N   1 ? 
ATOM   2441 C CA  . SER   B 1 10  ? 10.509  -14.337 35.501 1.000 18.022 0 10  SER   B CA  1 ? 
ATOM   2442 C C   . SER   B 1 10  ? 10.748  -14.094 36.999 1.000 17.393 0 10  SER   B C   1 ? 
ATOM   2443 O O   . SER   B 1 10  ? 11.571  -14.792 37.588 1.000 17.293 0 10  SER   B O   1 ? 
ATOM   2444 C CB  . SER   B 1 10  ? 11.766  -14.117 34.733 1.000 18.109 0 10  SER   B CB  1 ? 
ATOM   2445 O OG  . SER   B 1 10  ? 12.129  -12.748 34.819 1.000 18.969 0 10  SER   B OG  1 ? 
ATOM   2446 N N   . GLY   B 1 11  ? 10.044  -13.148 37.631 1.000 17.252 0 11  GLY   B N   1 ? 
ATOM   2447 C CA  . GLY   B 1 11  ? 10.343  -12.707 38.995 1.000 17.184 0 11  GLY   B CA  1 ? 
ATOM   2448 C C   . GLY   B 1 11  ? 10.315  -13.815 40.066 1.000 18.115 0 11  GLY   B C   1 ? 
ATOM   2449 O O   . GLY   B 1 11  ? 11.124  -13.825 41.003 1.000 17.787 0 11  GLY   B O   1 ? 
ATOM   2450 N N   . LYS   B 1 12  ? 9.385   -14.760 39.962 1.000 18.701 0 12  LYS   B N   1 ? 
ATOM   2451 C CA  . LYS   B 1 12  ? 9.328   -15.843 40.930 1.000 21.188 0 12  LYS   B CA  1 ? 
ATOM   2452 C C   . LYS   B 1 12  ? 10.590  -16.704 40.873 1.000 20.757 0 12  LYS   B C   1 ? 
ATOM   2453 O O   . LYS   B 1 12  ? 10.990  -17.261 41.892 1.000 22.083 0 12  LYS   B O   1 ? 
ATOM   2454 C CB  . LYS   B 1 12  ? 8.091   -16.699 40.685 1.000 24.653 0 12  LYS   B CB  1 ? 
ATOM   2455 C CG  . LYS   B 1 12  ? 6.806   -16.171 41.298 1.000 27.857 0 12  LYS   B CG  1 ? 
ATOM   2456 C CD  . LYS   B 1 12  ? 5.604   -16.921 40.792 1.000 32.613 0 12  LYS   B CD  1 ? 
ATOM   2457 C CE  . LYS   B 1 12  ? 4.371   -16.659 41.627 1.000 38.643 0 12  LYS   B CE  1 ? 
ATOM   2458 N NZ  . LYS   B 1 12  ? 4.294   -15.237 42.029 1.000 40.519 0 12  LYS   B NZ  1 ? 
ATOM   2459 N N   . VAL   B 1 13  ? 11.213  -16.814 39.689 1.000 19.272 0 13  VAL   B N   1 ? 
ATOM   2460 C CA  . VAL   B 1 13  ? 12.412  -17.618 39.513 1.000 17.792 0 13  VAL   B CA  1 ? 
ATOM   2461 C C   . VAL   B 1 13  ? 13.659  -16.821 39.899 1.000 18.588 0 13  VAL   B C   1 ? 
ATOM   2462 O O   . VAL   B 1 13  ? 14.593  -17.375 40.485 1.000 18.210 0 13  VAL   B O   1 ? 
ATOM   2463 C CB  . VAL   B 1 13  ? 12.518  -18.153 38.078 1.000 17.635 0 13  VAL   B CB  1 ? 
ATOM   2464 C CG1 . VAL   B 1 13  ? 13.811  -18.934 37.874 1.000 17.572 0 13  VAL   B CG1 1 ? 
ATOM   2465 C CG2 . VAL   B 1 13  ? 11.299  -18.986 37.711 1.000 17.548 0 13  VAL   B CG2 1 ? 
ATOM   2466 N N   . GLU   B 1 14  ? 13.664  -15.521 39.594 1.000 17.431 0 14  GLU   B N   1 ? 
ATOM   2467 C CA  . GLU   B 1 14  ? 14.788  -14.665 39.945 1.000 19.762 0 14  GLU   B CA  1 ? 
ATOM   2468 C C   . GLU   B 1 14  ? 15.081  -14.731 41.443 1.000 18.165 0 14  GLU   B C   1 ? 
ATOM   2469 O O   . GLU   B 1 14  ? 16.230  -14.735 41.846 1.000 17.684 0 14  GLU   B O   1 ? 
ATOM   2470 C CB  . GLU   B 1 14  ? 14.503  -13.203 39.584 1.000 19.491 0 14  GLU   B CB  1 ? 
ATOM   2471 C CG  . GLU   B 1 14  ? 14.391  -12.973 38.094 1.000 19.587 0 14  GLU   B CG  1 ? 
ATOM   2472 C CD  . GLU   B 1 14  ? 13.916  -11.578 37.746 1.000 20.268 0 14  GLU   B CD  1 ? 
ATOM   2473 O OE1 . GLU   B 1 14  ? 14.393  -10.629 38.395 1.000 21.101 0 14  GLU   B OE1 1 ? 
ATOM   2474 O OE2 . GLU   B 1 14  ? 13.058  -11.459 36.856 1.000 18.735 0 14  GLU   B OE2 1 ? 
ATOM   2475 N N   . GLY   B 1 15  ? 14.033  -14.780 42.263 1.000 19.898 0 15  GLY   B N   1 ? 
ATOM   2476 C CA  . GLY   B 1 15  ? 14.211  -14.795 43.706 1.000 21.319 0 15  GLY   B CA  1 ? 
ATOM   2477 C C   . GLY   B 1 15  ? 14.746  -16.133 44.210 1.000 22.110 0 15  GLY   B C   1 ? 
ATOM   2478 O O   . GLY   B 1 15  ? 14.924  -16.292 45.408 1.000 25.167 0 15  GLY   B O   1 ? 
ATOM   2479 N N   . CYS   B 1 16  ? 15.008  -17.086 43.299 1.000 22.840 0 16  CYS   B N   1 ? 
ATOM   2480 C CA  . CYS   B 1 16  ? 15.535  -18.392 43.666 1.000 20.221 0 16  CYS   B CA  1 ? 
ATOM   2481 C C   . CYS   B 1 16  ? 16.962  -18.620 43.162 1.000 19.696 0 16  CYS   B C   1 ? 
ATOM   2482 O O   . CYS   B 1 16  ? 17.562  -19.662 43.463 1.000 18.366 0 16  CYS   B O   1 ? 
ATOM   2483 C CB  . CYS   B 1 16  ? 14.651  -19.489 43.096 1.000 20.648 0 16  CYS   B CB  1 ? 
ATOM   2484 S SG  . CYS   B 1 16  ? 12.975  -19.454 43.772 1.000 22.129 0 16  CYS   B SG  1 ? 
ATOM   2485 N N   . MET   B 1 17  ? 17.507  -17.691 42.367 1.000 18.212 0 17  MET   B N   1 ? 
ATOM   2486 C CA  . MET   B 1 17  ? 18.780  -17.947 41.706 1.000 18.111 0 17  MET   B CA  1 ? 
ATOM   2487 C C   . MET   B 1 17  ? 19.915  -17.545 42.632 1.000 17.983 0 17  MET   B C   1 ? 
ATOM   2488 O O   . MET   B 1 17  ? 19.880  -16.458 43.205 1.000 17.993 0 17  MET   B O   1 ? 
ATOM   2489 C CB  . MET   B 1 17  ? 18.909  -17.154 40.402 1.000 18.209 0 17  MET   B CB  1 ? 
ATOM   2490 C CG  . MET   B 1 17  ? 17.860  -17.575 39.361 1.000 18.351 0 17  MET   B CG  1 ? 
ATOM   2491 S SD  . MET   B 1 17  ? 17.766  -19.369 39.073 1.000 18.692 0 17  MET   B SD  1 ? 
ATOM   2492 C CE  . MET   B 1 17  ? 19.429  -19.673 38.482 1.000 19.839 0 17  MET   B CE  1 ? 
ATOM   2493 N N   . VAL   B 1 18  ? 20.910  -18.427 42.762 1.000 17.984 0 18  VAL   B N   1 ? 
ATOM   2494 C CA  . VAL   B 1 18  ? 22.092  -18.112 43.547 1.000 18.227 0 18  VAL   B CA  1 ? 
ATOM   2495 C C   . VAL   B 1 18  ? 23.335  -18.497 42.761 1.000 17.730 0 18  VAL   B C   1 ? 
ATOM   2496 O O   . VAL   B 1 18  ? 23.261  -19.150 41.723 1.000 18.145 0 18  VAL   B O   1 ? 
ATOM   2497 C CB  . VAL   B 1 18  ? 22.079  -18.794 44.931 1.000 17.826 0 18  VAL   B CB  1 ? 
ATOM   2498 C CG1 . VAL   B 1 18  ? 20.888  -18.334 45.761 1.000 16.868 0 18  VAL   B CG1 1 ? 
ATOM   2499 C CG2 . VAL   B 1 18  ? 22.112  -20.313 44.828 1.000 17.450 0 18  VAL   B CG2 1 ? 
ATOM   2500 N N   . GLN   B 1 19  ? 24.473  -18.020 43.256 1.000 18.232 0 19  GLN   B N   1 ? 
ATOM   2501 C CA  . GLN   B 1 19  ? 25.758  -18.350 42.688 1.000 20.386 0 19  GLN   B CA  1 ? 
ATOM   2502 C C   . GLN   B 1 19  ? 26.316  -19.487 43.523 1.000 19.745 0 19  GLN   B C   1 ? 
ATOM   2503 O O   . GLN   B 1 19  ? 26.225  -19.418 44.735 1.000 18.976 0 19  GLN   B O   1 ? 
ATOM   2504 C CB  . GLN   B 1 19  ? 26.634  -17.103 42.710 1.000 23.959 0 19  GLN   B CB  1 ? 
ATOM   2505 C CG  . GLN   B 1 19  ? 28.051  -17.331 42.216 1.000 28.967 0 19  GLN   B CG  1 ? 
ATOM   2506 C CD  . GLN   B 1 19  ? 28.857  -16.056 42.310 1.000 33.044 0 19  GLN   B CD  1 ? 
ATOM   2507 O OE1 . GLN   B 1 19  ? 28.776  -15.323 43.287 1.000 37.289 0 19  GLN   B OE1 1 ? 
ATOM   2508 N NE2 . GLN   B 1 19  ? 29.611  -15.755 41.270 1.000 36.073 0 19  GLN   B NE2 1 ? 
ATOM   2509 N N   . VAL   B 1 20  ? 26.831  -20.537 42.861 1.000 19.987 0 20  VAL   B N   1 ? 
ATOM   2510 C CA  . VAL   B 1 20  ? 27.520  -21.642 43.510 1.000 17.409 0 20  VAL   B CA  1 ? 
ATOM   2511 C C   . VAL   B 1 20  ? 28.938  -21.703 42.944 1.000 19.641 0 20  VAL   B C   1 ? 
ATOM   2512 O O   . VAL   B 1 20  ? 29.118  -21.883 41.733 1.000 20.267 0 20  VAL   B O   1 ? 
ATOM   2513 C CB  . VAL   B 1 20  ? 26.809  -22.991 43.279 1.000 17.243 0 20  VAL   B CB  1 ? 
ATOM   2514 C CG1 . VAL   B 1 20  ? 27.532  -24.143 43.969 1.000 15.530 0 20  VAL   B CG1 1 ? 
ATOM   2515 C CG2 . VAL   B 1 20  ? 25.344  -22.966 43.703 1.000 17.546 0 20  VAL   B CG2 1 ? 
ATOM   2516 N N   . THR   B 1 21  ? 29.923  -21.600 43.843 1.000 19.256 0 21  THR   B N   1 ? 
ATOM   2517 C CA  . THR   B 1 21  ? 31.336  -21.742 43.528 1.000 21.169 0 21  THR   B CA  1 ? 
ATOM   2518 C C   . THR   B 1 21  ? 31.922  -22.945 44.261 1.000 22.396 0 21  THR   B C   1 ? 
ATOM   2519 O O   . THR   B 1 21  ? 31.701  -23.138 45.465 1.000 21.526 0 21  THR   B O   1 ? 
ATOM   2520 C CB  . THR   B 1 21  ? 32.132  -20.504 43.948 1.000 21.435 0 21  THR   B CB  1 ? 
ATOM   2521 O OG1 . THR   B 1 21  ? 31.543  -19.425 43.233 1.000 22.329 0 21  THR   B OG1 1 ? 
ATOM   2522 C CG2 . THR   B 1 21  ? 33.616  -20.601 43.662 1.000 21.711 0 21  THR   B CG2 1 ? 
ATOM   2523 N N   . CYS   B 1 22  ? 32.683  -23.730 43.498 1.000 24.911 0 22  CYS   B N   1 ? 
ATOM   2524 C CA  . CYS   B 1 22  ? 33.458  -24.835 44.022 1.000 25.022 0 22  CYS   B CA  1 ? 
ATOM   2525 C C   . CYS   B 1 22  ? 34.833  -24.831 43.360 1.000 25.151 0 22  CYS   B C   1 ? 
ATOM   2526 O O   . CYS   B 1 22  ? 34.957  -24.970 42.135 1.000 25.019 0 22  CYS   B O   1 ? 
ATOM   2527 C CB  . CYS   B 1 22  ? 32.735  -26.153 43.790 1.000 26.203 0 22  CYS   B CB  1 ? 
ATOM   2528 S SG  . CYS   B 1 22  ? 33.517  -27.535 44.666 1.000 26.992 0 22  CYS   B SG  1 ? 
ATOM   2529 N N   . GLY   B 1 23  ? 35.856  -24.580 44.178 1.000 26.170 0 23  GLY   B N   1 ? 
ATOM   2530 C CA  . GLY   B 1 23  ? 37.181  -24.259 43.670 1.000 27.189 0 23  GLY   B CA  1 ? 
ATOM   2531 C C   . GLY   B 1 23  ? 37.132  -23.128 42.644 1.000 27.800 0 23  GLY   B C   1 ? 
ATOM   2532 O O   . GLY   B 1 23  ? 36.679  -22.032 42.958 1.000 28.407 0 23  GLY   B O   1 ? 
ATOM   2533 N N   . THR   B 1 24  ? 37.481  -23.465 41.397 1.000 30.769 0 24  THR   B N   1 ? 
ATOM   2534 C CA  . THR   B 1 24  ? 37.601  -22.516 40.297 1.000 31.072 0 24  THR   B CA  1 ? 
ATOM   2535 C C   . THR   B 1 24  ? 36.344  -22.499 39.421 1.000 30.908 0 24  THR   B C   1 ? 
ATOM   2536 O O   . THR   B 1 24  ? 36.323  -21.806 38.419 1.000 34.185 0 24  THR   B O   1 ? 
ATOM   2537 C CB  . THR   B 1 24  ? 38.779  -22.910 39.394 1.000 31.252 0 24  THR   B CB  1 ? 
ATOM   2538 O OG1 . THR   B 1 24  ? 38.355  -24.074 38.691 1.000 37.578 0 24  THR   B OG1 1 ? 
ATOM   2539 C CG2 . THR   B 1 24  ? 40.062  -23.254 40.120 1.000 31.137 0 24  THR   B CG2 1 ? 
ATOM   2540 N N   . THR   B 1 25  ? 35.319  -23.305 39.740 1.000 30.941 0 25  THR   B N   1 ? 
ATOM   2541 C CA  . THR   B 1 25  ? 34.101  -23.341 38.944 1.000 28.368 0 25  THR   B CA  1 ? 
ATOM   2542 C C   . THR   B 1 25  ? 33.006  -22.557 39.662 1.000 25.659 0 25  THR   B C   1 ? 
ATOM   2543 O O   . THR   B 1 25  ? 32.701  -22.862 40.810 1.000 26.920 0 25  THR   B O   1 ? 
ATOM   2544 C CB  . THR   B 1 25  ? 33.620  -24.777 38.698 1.000 28.589 0 25  THR   B CB  1 ? 
ATOM   2545 O OG1 . THR   B 1 25  ? 34.616  -25.487 37.982 1.000 29.936 0 25  THR   B OG1 1 ? 
ATOM   2546 C CG2 . THR   B 1 25  ? 32.365  -24.863 37.863 1.000 29.677 0 25  THR   B CG2 1 ? 
ATOM   2547 N N   . THR   B 1 26  ? 32.441  -21.542 39.002 1.000 23.220 0 26  THR   B N   1 ? 
ATOM   2548 C CA  . THR   B 1 26  ? 31.229  -20.909 39.488 1.000 25.031 0 26  THR   B CA  1 ? 
ATOM   2549 C C   . THR   B 1 26  ? 30.143  -20.936 38.412 1.000 24.090 0 26  THR   B C   1 ? 
ATOM   2550 O O   . THR   B 1 26  ? 30.381  -20.745 37.221 1.000 25.117 0 26  THR   B O   1 ? 
ATOM   2551 C CB  . THR   B 1 26  ? 31.477  -19.546 40.154 1.000 28.646 0 26  THR   B CB  1 ? 
ATOM   2552 O OG1 . THR   B 1 26  ? 30.405  -18.654 39.846 1.000 30.393 0 26  THR   B OG1 1 ? 
ATOM   2553 C CG2 . THR   B 1 26  ? 32.781  -18.888 39.792 1.000 28.530 0 26  THR   B CG2 1 ? 
ATOM   2554 N N   . LEU   B 1 27  ? 28.940  -21.271 38.879 1.000 20.881 0 27  LEU   B N   1 ? 
ATOM   2555 C CA  . LEU   B 1 27  ? 27.751  -21.308 38.056 1.000 18.865 0 27  LEU   B CA  1 ? 
ATOM   2556 C C   . LEU   B 1 27  ? 26.552  -21.033 38.952 1.000 16.893 0 27  LEU   B C   1 ? 
ATOM   2557 O O   . LEU   B 1 27  ? 26.694  -20.462 40.038 1.000 15.638 0 27  LEU   B O   1 ? 
ATOM   2558 C CB  . LEU   B 1 27  ? 27.692  -22.660 37.335 1.000 19.099 0 27  LEU   B CB  1 ? 
ATOM   2559 C CG  . LEU   B 1 27  ? 28.069  -23.857 38.188 1.000 19.384 0 27  LEU   B CG  1 ? 
ATOM   2560 C CD1 . LEU   B 1 27  ? 27.054  -24.046 39.286 1.000 20.488 0 27  LEU   B CD1 1 ? 
ATOM   2561 C CD2 . LEU   B 1 27  ? 28.187  -25.114 37.347 1.000 20.749 0 27  LEU   B CD2 1 ? 
ATOM   2562 N N   . ASN   B 1 28  ? 25.360  -21.376 38.457 1.000 15.578 0 28  ASN   B N   1 ? 
ATOM   2563 C CA  . ASN   B 1 28  ? 24.125  -20.962 39.095 1.000 15.012 0 28  ASN   B CA  1 ? 
ATOM   2564 C C   . ASN   B 1 28  ? 23.481  -22.139 39.811 1.000 14.273 0 28  ASN   B C   1 ? 
ATOM   2565 O O   . ASN   B 1 28  ? 23.583  -23.289 39.391 1.000 13.512 0 28  ASN   B O   1 ? 
ATOM   2566 C CB  . ASN   B 1 28  ? 23.125  -20.433 38.063 1.000 16.435 0 28  ASN   B CB  1 ? 
ATOM   2567 C CG  . ASN   B 1 28  ? 23.743  -19.366 37.195 1.000 15.871 0 28  ASN   B CG  1 ? 
ATOM   2568 O OD1 . ASN   B 1 28  ? 23.968  -18.249 37.640 1.000 15.406 0 28  ASN   B OD1 1 ? 
ATOM   2569 N ND2 . ASN   B 1 28  ? 24.079  -19.731 35.977 1.000 16.498 0 28  ASN   B ND2 1 ? 
ATOM   2570 N N   . GLY   B 1 29  ? 22.757  -21.813 40.866 1.000 13.678 0 29  GLY   B N   1 ? 
ATOM   2571 C CA  . GLY   B 1 29  ? 21.946  -22.789 41.545 1.000 14.352 0 29  GLY   B CA  1 ? 
ATOM   2572 C C   . GLY   B 1 29  ? 20.550  -22.242 41.785 1.000 14.943 0 29  GLY   B C   1 ? 
ATOM   2573 O O   . GLY   B 1 29  ? 20.313  -21.028 41.745 1.000 13.499 0 29  GLY   B O   1 ? 
ATOM   2574 N N   . LEU   B 1 30  ? 19.661  -23.187 42.075 1.000 16.273 0 30  LEU   B N   1 ? 
ATOM   2575 C CA  . LEU   B 1 30  ? 18.264  -22.922 42.355 1.000 17.555 0 30  LEU   B CA  1 ? 
ATOM   2576 C C   . LEU   B 1 30  ? 18.005  -23.220 43.833 1.000 17.006 0 30  LEU   B C   1 ? 
ATOM   2577 O O   . LEU   B 1 30  ? 18.228  -24.337 44.302 1.000 16.102 0 30  LEU   B O   1 ? 
ATOM   2578 C CB  . LEU   B 1 30  ? 17.423  -23.789 41.407 1.000 17.310 0 30  LEU   B CB  1 ? 
ATOM   2579 C CG  . LEU   B 1 30  ? 15.915  -23.540 41.450 1.000 17.818 0 30  LEU   B CG  1 ? 
ATOM   2580 C CD1 . LEU   B 1 30  ? 15.587  -22.193 40.856 1.000 17.391 0 30  LEU   B CD1 1 ? 
ATOM   2581 C CD2 . LEU   B 1 30  ? 15.152  -24.631 40.705 1.000 16.795 0 30  LEU   B CD2 1 ? 
ATOM   2582 N N   . TRP   B 1 31  ? 17.593  -22.181 44.559 1.000 16.262 0 31  TRP   B N   1 ? 
ATOM   2583 C CA  . TRP   B 1 31  ? 17.425  -22.215 46.000 1.000 16.821 0 31  TRP   B CA  1 ? 
ATOM   2584 C C   . TRP   B 1 31  ? 15.941  -22.314 46.327 1.000 15.944 0 31  TRP   B C   1 ? 
ATOM   2585 O O   . TRP   B 1 31  ? 15.221  -21.338 46.176 1.000 17.233 0 31  TRP   B O   1 ? 
ATOM   2586 C CB  . TRP   B 1 31  ? 18.049  -20.942 46.596 1.000 17.337 0 31  TRP   B CB  1 ? 
ATOM   2587 C CG  . TRP   B 1 31  ? 18.045  -20.851 48.097 1.000 17.433 0 31  TRP   B CG  1 ? 
ATOM   2588 C CD1 . TRP   B 1 31  ? 17.962  -21.866 49.003 1.000 16.612 0 31  TRP   B CD1 1 ? 
ATOM   2589 C CD2 . TRP   B 1 31  ? 18.138  -19.624 48.861 1.000 16.733 0 31  TRP   B CD2 1 ? 
ATOM   2590 N NE1 . TRP   B 1 31  ? 18.023  -21.362 50.274 1.000 15.858 0 31  TRP   B NE1 1 ? 
ATOM   2591 C CE2 . TRP   B 1 31  ? 18.118  -19.992 50.221 1.000 16.477 0 31  TRP   B CE2 1 ? 
ATOM   2592 C CE3 . TRP   B 1 31  ? 18.197  -18.265 48.523 1.000 18.002 0 31  TRP   B CE3 1 ? 
ATOM   2593 C CZ2 . TRP   B 1 31  ? 18.173  -19.040 51.244 1.000 17.757 0 31  TRP   B CZ2 1 ? 
ATOM   2594 C CZ3 . TRP   B 1 31  ? 18.241  -17.322 49.531 1.000 19.475 0 31  TRP   B CZ3 1 ? 
ATOM   2595 C CH2 . TRP   B 1 31  ? 18.244  -17.711 50.876 1.000 19.400 0 31  TRP   B CH2 1 ? 
ATOM   2596 N N   . LEU   B 1 32  ? 15.488  -23.510 46.700 1.000 15.553 0 32  LEU   B N   1 ? 
ATOM   2597 C CA  . LEU   B 1 32  ? 14.108  -23.749 47.086 1.000 17.619 0 32  LEU   B CA  1 ? 
ATOM   2598 C C   . LEU   B 1 32  ? 14.090  -24.392 48.477 1.000 19.416 0 32  LEU   B C   1 ? 
ATOM   2599 O O   . LEU   B 1 32  ? 14.815  -25.358 48.724 1.000 18.588 0 32  LEU   B O   1 ? 
ATOM   2600 C CB  . LEU   B 1 32  ? 13.457  -24.680 46.064 1.000 18.196 0 32  LEU   B CB  1 ? 
ATOM   2601 C CG  . LEU   B 1 32  ? 13.476  -24.225 44.609 1.000 18.306 0 32  LEU   B CG  1 ? 
ATOM   2602 C CD1 . LEU   B 1 32  ? 12.939  -25.331 43.710 1.000 18.646 0 32  LEU   B CD1 1 ? 
ATOM   2603 C CD2 . LEU   B 1 32  ? 12.648  -22.971 44.428 1.000 18.711 0 32  LEU   B CD2 1 ? 
ATOM   2604 N N   . ASP   B 1 33  ? 13.295  -23.811 49.395 1.000 21.774 0 33  ASP   B N   1 ? 
ATOM   2605 C CA  . ASP   B 1 33  ? 13.350  -24.191 50.798 1.000 21.397 0 33  ASP   B CA  1 ? 
ATOM   2606 C C   . ASP   B 1 33  ? 14.811  -24.125 51.235 1.000 20.006 0 33  ASP   B C   1 ? 
ATOM   2607 O O   . ASP   B 1 33  ? 15.463  -23.106 51.027 1.000 19.318 0 33  ASP   B O   1 ? 
ATOM   2608 C CB  . ASP   B 1 33  ? 12.690  -25.555 51.023 1.000 21.812 0 33  ASP   B CB  1 ? 
ATOM   2609 C CG  . ASP   B 1 33  ? 11.252  -25.601 50.535 1.000 24.902 0 33  ASP   B CG  1 ? 
ATOM   2610 O OD1 . ASP   B 1 33  ? 10.534  -24.614 50.739 1.000 23.733 0 33  ASP   B OD1 1 ? 
ATOM   2611 O OD2 . ASP   B 1 33  ? 10.877  -26.615 49.931 1.000 29.658 0 33  ASP   B OD2 1 ? 
ATOM   2612 N N   . ASP   B 1 34  ? 15.337  -25.215 51.805 1.000 20.102 0 34  ASP   B N   1 ? 
ATOM   2613 C CA  . ASP   B 1 34  ? 16.678  -25.200 52.363 1.000 20.128 0 34  ASP   B CA  1 ? 
ATOM   2614 C C   . ASP   B 1 34  ? 17.617  -26.028 51.481 1.000 20.320 0 34  ASP   B C   1 ? 
ATOM   2615 O O   . ASP   B 1 34  ? 18.639  -26.541 51.954 1.000 23.327 0 34  ASP   B O   1 ? 
ATOM   2616 C CB  . ASP   B 1 34  ? 16.656  -25.642 53.829 1.000 20.472 0 34  ASP   B CB  1 ? 
ATOM   2617 C CG  . ASP   B 1 34  ? 16.108  -27.047 54.038 1.000 22.425 0 34  ASP   B CG  1 ? 
ATOM   2618 O OD1 . ASP   B 1 34  ? 15.445  -27.582 53.109 1.000 22.593 0 34  ASP   B OD1 1 ? 
ATOM   2619 O OD2 . ASP   B 1 34  ? 16.355  -27.608 55.126 1.000 24.668 0 34  ASP   B OD2 1 ? 
ATOM   2620 N N   . VAL   B 1 35  ? 17.282  -26.127 50.192 1.000 18.883 0 35  VAL   B N   1 ? 
ATOM   2621 C CA  . VAL   B 1 35  ? 18.087  -26.867 49.238 1.000 19.197 0 35  VAL   B CA  1 ? 
ATOM   2622 C C   . VAL   B 1 35  ? 18.460  -25.953 48.071 1.000 18.396 0 35  VAL   B C   1 ? 
ATOM   2623 O O   . VAL   B 1 35  ? 17.647  -25.164 47.584 1.000 17.191 0 35  VAL   B O   1 ? 
ATOM   2624 C CB  . VAL   B 1 35  ? 17.384  -28.140 48.736 1.000 19.893 0 35  VAL   B CB  1 ? 
ATOM   2625 C CG1 . VAL   B 1 35  ? 18.273  -28.899 47.765 1.000 20.968 0 35  VAL   B CG1 1 ? 
ATOM   2626 C CG2 . VAL   B 1 35  ? 16.986  -29.070 49.873 1.000 20.697 0 35  VAL   B CG2 1 ? 
ATOM   2627 N N   . VAL   B 1 36  ? 19.726  -26.038 47.667 1.000 17.414 0 36  VAL   B N   1 ? 
ATOM   2628 C CA  . VAL   B 1 36  ? 20.187  -25.416 46.445 1.000 18.421 0 36  VAL   B CA  1 ? 
ATOM   2629 C C   . VAL   B 1 36  ? 20.488  -26.522 45.441 1.000 17.603 0 36  VAL   B C   1 ? 
ATOM   2630 O O   . VAL   B 1 36  ? 21.255  -27.422 45.754 1.000 21.207 0 36  VAL   B O   1 ? 
ATOM   2631 C CB  . VAL   B 1 36  ? 21.407  -24.533 46.733 1.000 18.667 0 36  VAL   B CB  1 ? 
ATOM   2632 C CG1 . VAL   B 1 36  ? 22.067  -24.032 45.459 1.000 18.261 0 36  VAL   B CG1 1 ? 
ATOM   2633 C CG2 . VAL   B 1 36  ? 21.029  -23.366 47.628 1.000 19.710 0 36  VAL   B CG2 1 ? 
ATOM   2634 N N   . TYR   B 1 37  ? 19.850  -26.475 44.272 1.000 16.109 0 37  TYR   B N   1 ? 
ATOM   2635 C CA  . TYR   B 1 37  ? 20.062  -27.465 43.228 1.000 16.518 0 37  TYR   B CA  1 ? 
ATOM   2636 C C   . TYR   B 1 37  ? 20.971  -26.858 42.163 1.000 16.990 0 37  TYR   B C   1 ? 
ATOM   2637 O O   . TYR   B 1 37  ? 20.766  -25.699 41.778 1.000 15.858 0 37  TYR   B O   1 ? 
ATOM   2638 C CB  . TYR   B 1 37  ? 18.782  -27.966 42.558 1.000 16.557 0 37  TYR   B CB  1 ? 
ATOM   2639 C CG  . TYR   B 1 37  ? 17.712  -28.445 43.521 1.000 18.114 0 37  TYR   B CG  1 ? 
ATOM   2640 C CD1 . TYR   B 1 37  ? 17.016  -27.543 44.307 1.000 18.551 0 37  TYR   B CD1 1 ? 
ATOM   2641 C CD2 . TYR   B 1 37  ? 17.383  -29.795 43.621 1.000 20.052 0 37  TYR   B CD2 1 ? 
ATOM   2642 C CE1 . TYR   B 1 37  ? 16.031  -27.958 45.178 1.000 19.686 0 37  TYR   B CE1 1 ? 
ATOM   2643 C CE2 . TYR   B 1 37  ? 16.393  -30.227 44.485 1.000 20.983 0 37  TYR   B CE2 1 ? 
ATOM   2644 C CZ  . TYR   B 1 37  ? 15.734  -29.303 45.279 1.000 20.512 0 37  TYR   B CZ  1 ? 
ATOM   2645 O OH  . TYR   B 1 37  ? 14.781  -29.696 46.147 1.000 22.866 0 37  TYR   B OH  1 ? 
ATOM   2646 N N   . CYS   B 1 38  ? 21.964  -27.635 41.692 1.000 16.510 0 38  CYS   B N   1 ? 
ATOM   2647 C CA  . CYS   B 1 38  ? 22.873  -27.165 40.639 1.000 17.028 0 38  CYS   B CA  1 ? 
ATOM   2648 C C   . CYS   B 1 38  ? 23.472  -28.355 39.909 1.000 16.162 0 38  CYS   B C   1 ? 
ATOM   2649 O O   . CYS   B 1 38  ? 23.290  -29.488 40.344 1.000 15.789 0 38  CYS   B O   1 ? 
ATOM   2650 C CB  . CYS   B 1 38  ? 23.982  -26.255 41.159 1.000 16.940 0 38  CYS   B CB  1 ? 
ATOM   2651 S SG  . CYS   B 1 38  ? 25.197  -27.091 42.214 1.000 21.765 0 38  CYS   B SG  1 ? 
ATOM   2652 N N   . PRO   B 1 39  ? 24.112  -28.155 38.729 1.000 17.190 0 39  PRO   B N   1 ? 
ATOM   2653 C CA  . PRO   B 1 39  ? 24.711  -29.268 37.997 1.000 16.354 0 39  PRO   B CA  1 ? 
ATOM   2654 C C   . PRO   B 1 39  ? 25.877  -29.836 38.808 1.000 15.558 0 39  PRO   B C   1 ? 
ATOM   2655 O O   . PRO   B 1 39  ? 26.650  -29.063 39.378 1.000 14.873 0 39  PRO   B O   1 ? 
ATOM   2656 C CB  . PRO   B 1 39  ? 25.195  -28.626 36.695 1.000 16.477 0 39  PRO   B CB  1 ? 
ATOM   2657 C CG  . PRO   B 1 39  ? 24.380  -27.348 36.585 1.000 17.006 0 39  PRO   B CG  1 ? 
ATOM   2658 C CD  . PRO   B 1 39  ? 24.273  -26.877 38.015 1.000 17.056 0 39  PRO   B CD  1 ? 
ATOM   2659 N N   . ARG   B 1 40  ? 26.001  -31.165 38.843 1.000 14.220 0 40  ARG   B N   1 ? 
ATOM   2660 C CA  . ARG   B 1 40  ? 26.978  -31.810 39.709 1.000 15.432 0 40  ARG   B CA  1 ? 
ATOM   2661 C C   . ARG   B 1 40  ? 28.400  -31.544 39.201 1.000 15.803 0 40  ARG   B C   1 ? 
ATOM   2662 O O   . ARG   B 1 40  ? 29.358  -31.653 39.953 1.000 16.307 0 40  ARG   B O   1 ? 
ATOM   2663 C CB  . ARG   B 1 40  ? 26.701  -33.307 39.836 1.000 15.109 0 40  ARG   B CB  1 ? 
ATOM   2664 C CG  . ARG   B 1 40  ? 26.783  -34.082 38.531 1.000 15.741 0 40  ARG   B CG  1 ? 
ATOM   2665 C CD  . ARG   B 1 40  ? 26.752  -35.577 38.771 1.000 17.191 0 40  ARG   B CD  1 ? 
ATOM   2666 N NE  . ARG   B 1 40  ? 26.722  -36.318 37.520 1.000 18.054 0 40  ARG   B NE  1 ? 
ATOM   2667 C CZ  . ARG   B 1 40  ? 26.696  -37.650 37.408 1.000 19.386 0 40  ARG   B CZ  1 ? 
ATOM   2668 N NH1 . ARG   B 1 40  ? 26.594  -38.418 38.492 1.000 17.922 0 40  ARG   B NH1 1 ? 
ATOM   2669 N NH2 . ARG   B 1 40  ? 26.760  -38.198 36.199 1.000 18.829 0 40  ARG   B NH2 1 ? 
ATOM   2670 N N   . HIS   B 1 41  ? 28.548  -31.146 37.938 1.000 15.874 0 41  HIS   B N   1 ? 
ATOM   2671 C CA  . HIS   B 1 41  ? 29.876  -30.918 37.390 1.000 16.658 0 41  HIS   B CA  1 ? 
ATOM   2672 C C   . HIS   B 1 41  ? 30.522  -29.680 37.996 1.000 15.662 0 41  HIS   B C   1 ? 
ATOM   2673 O O   . HIS   B 1 41  ? 31.699  -29.431 37.756 1.000 15.133 0 41  HIS   B O   1 ? 
ATOM   2674 C CB  . HIS   B 1 41  ? 29.904  -30.885 35.857 1.000 17.483 0 41  HIS   B CB  1 ? 
ATOM   2675 C CG  . HIS   B 1 41  ? 29.154  -29.766 35.224 1.000 17.767 0 41  HIS   B CG  1 ? 
ATOM   2676 N ND1 . HIS   B 1 41  ? 27.851  -29.962 34.816 1.000 16.773 0 41  HIS   B ND1 1 ? 
ATOM   2677 C CD2 . HIS   B 1 41  ? 29.484  -28.508 34.883 1.000 18.906 0 41  HIS   B CD2 1 ? 
ATOM   2678 C CE1 . HIS   B 1 41  ? 27.404  -28.835 34.245 1.000 19.873 0 41  HIS   B CE1 1 ? 
ATOM   2679 N NE2 . HIS   B 1 41  ? 28.370  -27.926 34.288 1.000 19.521 0 41  HIS   B NE2 1 ? 
ATOM   2680 N N   . VAL   B 1 42  ? 29.789  -28.949 38.832 1.000 15.427 0 42  VAL   B N   1 ? 
ATOM   2681 C CA  . VAL   B 1 42  ? 30.417  -27.883 39.584 1.000 16.157 0 42  VAL   B CA  1 ? 
ATOM   2682 C C   . VAL   B 1 42  ? 31.595  -28.402 40.422 1.000 17.849 0 42  VAL   B C   1 ? 
ATOM   2683 O O   . VAL   B 1 42  ? 32.488  -27.629 40.749 1.000 17.096 0 42  VAL   B O   1 ? 
ATOM   2684 C CB  . VAL   B 1 42  ? 29.391  -27.146 40.457 1.000 15.859 0 42  VAL   B CB  1 ? 
ATOM   2685 C CG1 . VAL   B 1 42  ? 28.911  -28.017 41.598 1.000 15.175 0 42  VAL   B CG1 1 ? 
ATOM   2686 C CG2 . VAL   B 1 42  ? 29.946  -25.829 40.959 1.000 15.274 0 42  VAL   B CG2 1 ? 
ATOM   2687 N N   . ILE   B 1 43  ? 31.615  -29.695 40.762 1.000 20.517 0 43  ILE   B N   1 ? 
ATOM   2688 C CA  . ILE   B 1 43  ? 32.662  -30.239 41.619 1.000 24.513 0 43  ILE   B CA  1 ? 
ATOM   2689 C C   . ILE   B 1 43  ? 33.926  -30.617 40.834 1.000 28.204 0 43  ILE   B C   1 ? 
ATOM   2690 O O   . ILE   B 1 43  ? 34.927  -30.903 41.462 1.000 32.202 0 43  ILE   B O   1 ? 
ATOM   2691 C CB  . ILE   B 1 43  ? 32.134  -31.442 42.430 1.000 23.602 0 43  ILE   B CB  1 ? 
ATOM   2692 C CG1 . ILE   B 1 43  ? 31.852  -32.681 41.578 1.000 21.026 0 43  ILE   B CG1 1 ? 
ATOM   2693 C CG2 . ILE   B 1 43  ? 30.902  -31.039 43.211 1.000 24.653 0 43  ILE   B CG2 1 ? 
ATOM   2694 C CD1 . ILE   B 1 43  ? 31.226  -33.799 42.356 1.000 22.095 0 43  ILE   B CD1 1 ? 
ATOM   2695 N N   . CYS   B 1 44  ? 33.904  -30.588 39.493 1.000 32.330 0 44  CYS   B N   1 ? 
ATOM   2696 C CA  . CYS   B 1 44  ? 35.039  -30.997 38.675 1.000 35.912 0 44  CYS   B CA  1 ? 
ATOM   2697 C C   . CYS   B 1 44  ? 36.049  -29.878 38.437 1.000 39.639 0 44  CYS   B C   1 ? 
ATOM   2698 O O   . CYS   B 1 44  ? 35.657  -28.751 38.179 1.000 41.347 0 44  CYS   B O   1 ? 
ATOM   2699 C CB  . CYS   B 1 44  ? 34.590  -31.396 37.279 1.000 33.403 0 44  CYS   B CB  1 ? 
ATOM   2700 S SG  . CYS   B 1 44  ? 33.384  -32.735 37.325 1.000 38.780 0 44  CYS   B SG  1 ? 
ATOM   2701 N N   . THR   B 1 45  ? 37.341  -30.237 38.432 1.000 46.123 0 45  THR   B N   1 ? 
ATOM   2702 C CA  . THR   B 1 45  ? 38.370  -29.477 37.724 1.000 52.226 0 45  THR   B CA  1 ? 
ATOM   2703 C C   . THR   B 1 45  ? 38.340  -29.828 36.233 1.000 54.128 0 45  THR   B C   1 ? 
ATOM   2704 O O   . THR   B 1 45  ? 37.595  -30.713 35.808 1.000 53.237 0 45  THR   B O   1 ? 
ATOM   2705 C CB  . THR   B 1 45  ? 39.779  -29.783 38.250 1.000 50.091 0 45  THR   B CB  1 ? 
ATOM   2706 O OG1 . THR   B 1 45  ? 40.127  -31.076 37.747 1.000 54.810 0 45  THR   B OG1 1 ? 
ATOM   2707 C CG2 . THR   B 1 45  ? 39.884  -29.735 39.760 1.000 49.087 0 45  THR   B CG2 1 ? 
ATOM   2708 N N   . SER   B 1 46  ? 39.196  -29.169 35.441 1.000 57.018 0 46  SER   B N   1 ? 
ATOM   2709 C CA  . SER   B 1 46  ? 39.221  -29.398 34.002 1.000 59.820 0 46  SER   B CA  1 ? 
ATOM   2710 C C   . SER   B 1 46  ? 39.665  -30.831 33.707 1.000 54.447 0 46  SER   B C   1 ? 
ATOM   2711 O O   . SER   B 1 46  ? 39.064  -31.509 32.875 1.000 50.298 0 46  SER   B O   1 ? 
ATOM   2712 C CB  . SER   B 1 46  ? 40.082  -28.387 33.291 1.000 58.541 0 46  SER   B CB  1 ? 
ATOM   2713 O OG  . SER   B 1 46  ? 39.449  -27.977 32.089 1.000 60.289 0 46  SER   B OG  1 ? 
ATOM   2714 N N   . GLU   B 1 47  ? 40.688  -31.292 34.438 1.000 59.037 0 47  GLU   B N   1 ? 
ATOM   2715 C CA  . GLU   B 1 47  ? 41.208  -32.643 34.292 1.000 64.272 0 47  GLU   B CA  1 ? 
ATOM   2716 C C   . GLU   B 1 47  ? 40.120  -33.676 34.610 1.000 63.503 0 47  GLU   B C   1 ? 
ATOM   2717 O O   . GLU   B 1 47  ? 39.958  -34.650 33.877 1.000 58.117 0 47  GLU   B O   1 ? 
ATOM   2718 C CB  . GLU   B 1 47  ? 42.445  -32.825 35.180 1.000 69.861 0 47  GLU   B CB  1 ? 
ATOM   2719 C CG  . GLU   B 1 47  ? 43.214  -34.111 34.896 1.000 78.266 0 47  GLU   B CG  1 ? 
ATOM   2720 C CD  . GLU   B 1 47  ? 43.953  -34.169 33.562 1.000 84.881 0 47  GLU   B CD  1 ? 
ATOM   2721 O OE1 . GLU   B 1 47  ? 43.377  -34.701 32.575 1.000 81.620 0 47  GLU   B OE1 1 ? 
ATOM   2722 O OE2 . GLU   B 1 47  ? 45.122  -33.715 33.513 1.000 76.796 0 47  GLU   B OE2 1 ? 
ATOM   2723 N N   . ASP   B 1 48  ? 39.365  -33.458 35.699 1.000 62.636 0 48  ASP   B N   1 ? 
ATOM   2724 C CA  . ASP   B 1 48  ? 38.302  -34.368 36.115 1.000 62.127 0 48  ASP   B CA  1 ? 
ATOM   2725 C C   . ASP   B 1 48  ? 37.331  -34.684 34.972 1.000 59.633 0 48  ASP   B C   1 ? 
ATOM   2726 O O   . ASP   B 1 48  ? 36.839  -35.806 34.884 1.000 56.996 0 48  ASP   B O   1 ? 
ATOM   2727 C CB  . ASP   B 1 48  ? 37.502  -33.796 37.290 1.000 61.469 0 48  ASP   B CB  1 ? 
ATOM   2728 C CG  . ASP   B 1 48  ? 38.280  -33.744 38.595 1.000 61.547 0 48  ASP   B CG  1 ? 
ATOM   2729 O OD1 . ASP   B 1 48  ? 38.808  -34.801 38.998 1.000 61.288 0 48  ASP   B OD1 1 ? 
ATOM   2730 O OD2 . ASP   B 1 48  ? 38.346  -32.653 39.200 1.000 56.625 0 48  ASP   B OD2 1 ? 
ATOM   2731 N N   . MET   B 1 49  ? 37.083  -33.702 34.093 1.000 55.076 0 49  MET   B N   1 ? 
ATOM   2732 C CA  . MET   B 1 49  ? 35.953  -33.710 33.172 1.000 52.949 0 49  MET   B CA  1 ? 
ATOM   2733 C C   . MET   B 1 49  ? 36.066  -34.762 32.063 1.000 48.477 0 49  MET   B C   1 ? 
ATOM   2734 O O   . MET   B 1 49  ? 35.083  -34.986 31.364 1.000 41.336 0 49  MET   B O   1 ? 
ATOM   2735 C CB  . MET   B 1 49  ? 35.798  -32.323 32.536 1.000 51.433 0 49  MET   B CB  1 ? 
ATOM   2736 C CG  . MET   B 1 49  ? 35.262  -31.306 33.509 1.000 51.301 0 49  MET   B CG  1 ? 
ATOM   2737 S SD  . MET   B 1 49  ? 33.452  -31.255 33.550 1.000 63.550 0 49  MET   B SD  1 ? 
ATOM   2738 C CE  . MET   B 1 49  ? 33.179  -30.205 32.121 1.000 58.676 0 49  MET   B CE  1 ? 
ATOM   2739 N N   . LEU   B 1 50  ? 37.232  -35.406 31.901 1.000 50.699 0 50  LEU   B N   1 ? 
ATOM   2740 C CA  . LEU   B 1 50  ? 37.422  -36.451 30.896 1.000 54.862 0 50  LEU   B CA  1 ? 
ATOM   2741 C C   . LEU   B 1 50  ? 36.473  -37.627 31.160 1.000 47.423 0 50  LEU   B C   1 ? 
ATOM   2742 O O   . LEU   B 1 50  ? 35.627  -37.943 30.329 1.000 44.969 0 50  LEU   B O   1 ? 
ATOM   2743 C CB  . LEU   B 1 50  ? 38.897  -36.879 30.895 1.000 64.633 0 50  LEU   B CB  1 ? 
ATOM   2744 C CG  . LEU   B 1 50  ? 39.855  -35.999 30.080 1.000 74.478 0 50  LEU   B CG  1 ? 
ATOM   2745 C CD1 . LEU   B 1 50  ? 39.757  -34.524 30.460 1.000 76.143 0 50  LEU   B CD1 1 ? 
ATOM   2746 C CD2 . LEU   B 1 50  ? 41.295  -36.467 30.239 1.000 76.979 0 50  LEU   B CD2 1 ? 
ATOM   2747 N N   . ASN   B 1 51  ? 36.582  -38.250 32.338 1.000 44.516 0 51  ASN   B N   1 ? 
ATOM   2748 C CA  . ASN   B 1 51  ? 35.547  -39.157 32.809 1.000 39.157 0 51  ASN   B CA  1 ? 
ATOM   2749 C C   . ASN   B 1 51  ? 35.418  -38.965 34.322 1.000 33.860 0 51  ASN   B C   1 ? 
ATOM   2750 O O   . ASN   B 1 51  ? 36.189  -39.507 35.112 1.000 29.170 0 51  ASN   B O   1 ? 
ATOM   2751 C CB  . ASN   B 1 51  ? 35.838  -40.599 32.367 1.000 50.670 0 51  ASN   B CB  1 ? 
ATOM   2752 C CG  . ASN   B 1 51  ? 34.673  -41.218 31.613 1.000 47.669 0 51  ASN   B CG  1 ? 
ATOM   2753 O OD1 . ASN   B 1 51  ? 34.810  -41.591 30.450 1.000 35.631 0 51  ASN   B OD1 1 ? 
ATOM   2754 N ND2 . ASN   B 1 51  ? 33.514  -41.280 32.255 1.000 50.923 0 51  ASN   B ND2 1 ? 
ATOM   2755 N N   . PRO   B 1 52  ? 34.512  -38.085 34.794 1.000 27.871 0 52  PRO   B N   1 ? 
ATOM   2756 C CA  . PRO   B 1 52  ? 34.455  -37.775 36.218 1.000 27.236 0 52  PRO   B CA  1 ? 
ATOM   2757 C C   . PRO   B 1 52  ? 33.842  -38.951 36.960 1.000 26.666 0 52  PRO   B C   1 ? 
ATOM   2758 O O   . PRO   B 1 52  ? 32.817  -39.467 36.528 1.000 26.379 0 52  PRO   B O   1 ? 
ATOM   2759 C CB  . PRO   B 1 52  ? 33.577  -36.511 36.244 1.000 28.423 0 52  PRO   B CB  1 ? 
ATOM   2760 C CG  . PRO   B 1 52  ? 32.667  -36.692 35.041 1.000 28.804 0 52  PRO   B CG  1 ? 
ATOM   2761 C CD  . PRO   B 1 52  ? 33.568  -37.295 33.994 1.000 27.229 0 52  PRO   B CD  1 ? 
ATOM   2762 N N   . ASN   B 1 53  ? 34.507  -39.398 38.034 1.000 26.677 0 53  ASN   B N   1 ? 
ATOM   2763 C CA  . ASN   B 1 53  ? 33.899  -40.304 39.001 1.000 25.900 0 53  ASN   B CA  1 ? 
ATOM   2764 C C   . ASN   B 1 53  ? 33.201  -39.439 40.047 1.000 22.345 0 53  ASN   B C   1 ? 
ATOM   2765 O O   . ASN   B 1 53  ? 33.776  -39.124 41.087 1.000 20.714 0 53  ASN   B O   1 ? 
ATOM   2766 C CB  . ASN   B 1 53  ? 34.919  -41.252 39.658 1.000 26.460 0 53  ASN   B CB  1 ? 
ATOM   2767 C CG  . ASN   B 1 53  ? 34.277  -42.311 40.539 1.000 27.715 0 53  ASN   B CG  1 ? 
ATOM   2768 O OD1 . ASN   B 1 53  ? 33.165  -42.143 41.043 1.000 27.821 0 53  ASN   B OD1 1 ? 
ATOM   2769 N ND2 . ASN   B 1 53  ? 34.965  -43.426 40.729 1.000 28.255 0 53  ASN   B ND2 1 ? 
ATOM   2770 N N   . TYR   B 1 54  ? 31.962  -39.065 39.743 1.000 20.871 0 54  TYR   B N   1 ? 
ATOM   2771 C CA  . TYR   B 1 54  ? 31.233  -38.079 40.517 1.000 22.105 0 54  TYR   B CA  1 ? 
ATOM   2772 C C   . TYR   B 1 54  ? 31.145  -38.492 41.987 1.000 24.040 0 54  TYR   B C   1 ? 
ATOM   2773 O O   . TYR   B 1 54  ? 31.362  -37.653 42.868 1.000 20.310 0 54  TYR   B O   1 ? 
ATOM   2774 C CB  . TYR   B 1 54  ? 29.900  -37.831 39.813 1.000 22.964 0 54  TYR   B CB  1 ? 
ATOM   2775 C CG  . TYR   B 1 54  ? 30.052  -36.864 38.645 1.000 22.837 0 54  TYR   B CG  1 ? 
ATOM   2776 C CD1 . TYR   B 1 54  ? 30.473  -35.559 38.870 1.000 24.223 0 54  TYR   B CD1 1 ? 
ATOM   2777 C CD2 . TYR   B 1 54  ? 29.834  -37.252 37.328 1.000 23.769 0 54  TYR   B CD2 1 ? 
ATOM   2778 C CE1 . TYR   B 1 54  ? 30.624  -34.649 37.834 1.000 23.596 0 54  TYR   B CE1 1 ? 
ATOM   2779 C CE2 . TYR   B 1 54  ? 29.960  -36.345 36.280 1.000 24.492 0 54  TYR   B CE2 1 ? 
ATOM   2780 C CZ  . TYR   B 1 54  ? 30.368  -35.039 36.534 1.000 23.766 0 54  TYR   B CZ  1 ? 
ATOM   2781 O OH  . TYR   B 1 54  ? 30.560  -34.121 35.524 1.000 22.882 0 54  TYR   B OH  1 ? 
ATOM   2782 N N   . GLU   B 1 55  ? 30.863  -39.775 42.240 1.000 24.825 0 55  GLU   B N   1 ? 
ATOM   2783 C CA  . GLU   B 1 55  ? 30.662  -40.237 43.601 1.000 29.794 0 55  GLU   B CA  1 ? 
ATOM   2784 C C   . GLU   B 1 55  ? 31.963  -40.076 44.378 1.000 28.608 0 55  GLU   B C   1 ? 
ATOM   2785 O O   . GLU   B 1 55  ? 31.969  -39.578 45.492 1.000 27.802 0 55  GLU   B O   1 ? 
ATOM   2786 C CB  . GLU   B 1 55  ? 30.136  -41.673 43.659 1.000 35.131 0 55  GLU   B CB  1 ? 
ATOM   2787 C CG  . GLU   B 1 55  ? 28.734  -41.760 44.252 1.000 48.059 0 55  GLU   B CG  1 ? 
ATOM   2788 C CD  . GLU   B 1 55  ? 28.481  -40.922 45.510 1.000 61.998 0 55  GLU   B CD  1 ? 
ATOM   2789 O OE1 . GLU   B 1 55  ? 27.400  -40.274 45.590 1.000 67.889 0 55  GLU   B OE1 1 ? 
ATOM   2790 O OE2 . GLU   B 1 55  ? 29.367  -40.884 46.409 1.000 61.169 0 55  GLU   B OE2 1 ? 
ATOM   2791 N N   . ASP   B 1 56  ? 33.070  -40.453 43.755 1.000 29.980 0 56  ASP   B N   1 ? 
ATOM   2792 C CA  . ASP   B 1 56  ? 34.372  -40.334 44.376 1.000 30.899 0 56  ASP   B CA  1 ? 
ATOM   2793 C C   . ASP   B 1 56  ? 34.735  -38.871 44.643 1.000 28.352 0 56  ASP   B C   1 ? 
ATOM   2794 O O   . ASP   B 1 56  ? 35.331  -38.549 45.673 1.000 26.394 0 56  ASP   B O   1 ? 
ATOM   2795 C CB  . ASP   B 1 56  ? 35.415  -40.978 43.475 1.000 34.346 0 56  ASP   B CB  1 ? 
ATOM   2796 C CG  . ASP   B 1 56  ? 36.748  -41.051 44.168 1.000 42.908 0 56  ASP   B CG  1 ? 
ATOM   2797 O OD1 . ASP   B 1 56  ? 36.864  -41.908 45.054 1.000 52.322 0 56  ASP   B OD1 1 ? 
ATOM   2798 O OD2 . ASP   B 1 56  ? 37.623  -40.207 43.856 1.000 46.406 0 56  ASP   B OD2 1 ? 
ATOM   2799 N N   . LEU   B 1 57  ? 34.454  -37.990 43.673 1.000 25.934 0 57  LEU   B N   1 ? 
ATOM   2800 C CA  . LEU   B 1 57  ? 34.772  -36.570 43.816 1.000 25.142 0 57  LEU   B CA  1 ? 
ATOM   2801 C C   . LEU   B 1 57  ? 33.961  -35.949 44.955 1.000 24.391 0 57  LEU   B C   1 ? 
ATOM   2802 O O   . LEU   B 1 57  ? 34.504  -35.149 45.714 1.000 24.742 0 57  LEU   B O   1 ? 
ATOM   2803 C CB  . LEU   B 1 57  ? 34.480  -35.838 42.504 1.000 24.458 0 57  LEU   B CB  1 ? 
ATOM   2804 C CG  . LEU   B 1 57  ? 35.367  -36.225 41.332 1.000 26.303 0 57  LEU   B CG  1 ? 
ATOM   2805 C CD1 . LEU   B 1 57  ? 34.788  -35.708 40.023 1.000 26.754 0 57  LEU   B CD1 1 ? 
ATOM   2806 C CD2 . LEU   B 1 57  ? 36.789  -35.707 41.539 1.000 28.412 0 57  LEU   B CD2 1 ? 
ATOM   2807 N N   . LEU   B 1 58  ? 32.672  -36.328 45.076 1.000 21.537 0 58  LEU   B N   1 ? 
ATOM   2808 C CA  . LEU   B 1 58  ? 31.790  -35.691 46.037 1.000 23.607 0 58  LEU   B CA  1 ? 
ATOM   2809 C C   . LEU   B 1 58  ? 32.148  -36.086 47.473 1.000 24.641 0 58  LEU   B C   1 ? 
ATOM   2810 O O   . LEU   B 1 58  ? 32.178  -35.226 48.344 1.000 29.457 0 58  LEU   B O   1 ? 
ATOM   2811 C CB  . LEU   B 1 58  ? 30.335  -36.029 45.721 1.000 24.070 0 58  LEU   B CB  1 ? 
ATOM   2812 C CG  . LEU   B 1 58  ? 29.340  -35.202 46.524 1.000 25.709 0 58  LEU   B CG  1 ? 
ATOM   2813 C CD1 . LEU   B 1 58  ? 29.528  -33.722 46.233 1.000 25.863 0 58  LEU   B CD1 1 ? 
ATOM   2814 C CD2 . LEU   B 1 58  ? 27.911  -35.622 46.249 1.000 27.475 0 58  LEU   B CD2 1 ? 
ATOM   2815 N N   . ILE   B 1 59  ? 32.467  -37.368 47.694 1.000 26.000 0 59  ILE   B N   1 ? 
ATOM   2816 C CA  . ILE   B 1 59  ? 33.029  -37.864 48.947 1.000 27.349 0 59  ILE   B CA  1 ? 
ATOM   2817 C C   . ILE   B 1 59  ? 34.189  -36.991 49.418 1.000 24.683 0 59  ILE   B C   1 ? 
ATOM   2818 O O   . ILE   B 1 59  ? 34.336  -36.719 50.596 1.000 24.542 0 59  ILE   B O   1 ? 
ATOM   2819 C CB  . ILE   B 1 59  ? 33.472  -39.335 48.785 1.000 30.572 0 59  ILE   B CB  1 ? 
ATOM   2820 C CG1 . ILE   B 1 59  ? 32.259  -40.248 48.590 1.000 35.188 0 59  ILE   B CG1 1 ? 
ATOM   2821 C CG2 . ILE   B 1 59  ? 34.336  -39.787 49.960 1.000 31.674 0 59  ILE   B CG2 1 ? 
ATOM   2822 C CD1 . ILE   B 1 59  ? 32.577  -41.635 48.034 1.000 38.959 0 59  ILE   B CD1 1 ? 
ATOM   2823 N N   . ARG   B 1 60  ? 35.043  -36.554 48.506 1.000 26.711 0 60  ARG   B N   1 ? 
ATOM   2824 C CA  . ARG   B 1 60  ? 36.244  -35.838 48.902 1.000 28.748 0 60  ARG   B CA  1 ? 
ATOM   2825 C C   . ARG   B 1 60  ? 35.946  -34.352 49.119 1.000 29.178 0 60  ARG   B C   1 ? 
ATOM   2826 O O   . ARG   B 1 60  ? 36.803  -33.616 49.612 1.000 27.262 0 60  ARG   B O   1 ? 
ATOM   2827 C CB  . ARG   B 1 60  ? 37.337  -36.116 47.866 1.000 33.957 0 60  ARG   B CB  1 ? 
ATOM   2828 C CG  . ARG   B 1 60  ? 37.822  -37.559 47.932 1.000 40.544 0 60  ARG   B CG  1 ? 
ATOM   2829 C CD  . ARG   B 1 60  ? 38.520  -38.065 46.689 1.000 47.416 0 60  ARG   B CD  1 ? 
ATOM   2830 N NE  . ARG   B 1 60  ? 39.834  -37.473 46.531 1.000 58.696 0 60  ARG   B NE  1 ? 
ATOM   2831 C CZ  . ARG   B 1 60  ? 40.532  -37.463 45.398 1.000 69.001 0 60  ARG   B CZ  1 ? 
ATOM   2832 N NH1 . ARG   B 1 60  ? 41.733  -36.911 45.374 1.000 66.071 0 60  ARG   B NH1 1 ? 
ATOM   2833 N NH2 . ARG   B 1 60  ? 40.030  -37.997 44.293 1.000 71.913 0 60  ARG   B NH2 1 ? 
ATOM   2834 N N   . LYS   B 1 61  ? 34.723  -33.906 48.799 1.000 25.224 0 61  LYS   B N   1 ? 
ATOM   2835 C CA  . LYS   B 1 61  ? 34.366  -32.513 49.026 1.000 25.086 0 61  LYS   B CA  1 ? 
ATOM   2836 C C   . LYS   B 1 61  ? 33.919  -32.292 50.476 1.000 22.744 0 61  LYS   B C   1 ? 
ATOM   2837 O O   . LYS   B 1 61  ? 33.356  -33.169 51.125 1.000 21.238 0 61  LYS   B O   1 ? 
ATOM   2838 C CB  . LYS   B 1 61  ? 33.285  -32.061 48.034 1.000 26.402 0 61  LYS   B CB  1 ? 
ATOM   2839 C CG  . LYS   B 1 61  ? 33.737  -31.926 46.576 1.000 28.907 0 61  LYS   B CG  1 ? 
ATOM   2840 C CD  . LYS   B 1 61  ? 34.876  -30.938 46.361 1.000 32.886 0 61  LYS   B CD  1 ? 
ATOM   2841 C CE  . LYS   B 1 61  ? 35.626  -31.143 45.066 1.000 39.686 0 61  LYS   B CE  1 ? 
ATOM   2842 N NZ  . LYS   B 1 61  ? 36.839  -30.294 45.007 1.000 42.518 0 61  LYS   B NZ  1 ? 
ATOM   2843 N N   . SER   B 1 62  ? 34.199  -31.086 50.965 1.000 21.213 0 62  SER   B N   1 ? 
ATOM   2844 C CA  . SER   B 1 62  ? 33.712  -30.591 52.238 1.000 20.017 0 62  SER   B CA  1 ? 
ATOM   2845 C C   . SER   B 1 62  ? 32.549  -29.655 51.971 1.000 20.122 0 62  SER   B C   1 ? 
ATOM   2846 O O   . SER   B 1 62  ? 32.502  -29.021 50.913 1.000 21.821 0 62  SER   B O   1 ? 
ATOM   2847 C CB  . SER   B 1 62  ? 34.815  -29.898 52.980 1.000 20.828 0 62  SER   B CB  1 ? 
ATOM   2848 O OG  . SER   B 1 62  ? 34.313  -29.188 54.091 1.000 21.879 0 62  SER   B OG  1 ? 
ATOM   2849 N N   . ASN   B 1 63  ? 31.611  -29.586 52.919 1.000 19.067 0 63  ASN   B N   1 ? 
ATOM   2850 C CA  . ASN   B 1 63  ? 30.562  -28.591 52.869 1.000 21.041 0 63  ASN   B CA  1 ? 
ATOM   2851 C C   . ASN   B 1 63  ? 31.162  -27.213 52.631 1.000 22.047 0 63  ASN   B C   1 ? 
ATOM   2852 O O   . ASN   B 1 63  ? 30.601  -26.425 51.852 1.000 21.575 0 63  ASN   B O   1 ? 
ATOM   2853 C CB  . ASN   B 1 63  ? 29.697  -28.574 54.127 1.000 21.744 0 63  ASN   B CB  1 ? 
ATOM   2854 C CG  . ASN   B 1 63  ? 28.826  -29.808 54.212 1.000 22.629 0 63  ASN   B CG  1 ? 
ATOM   2855 O OD1 . ASN   B 1 63  ? 28.258  -30.264 53.217 1.000 23.863 0 63  ASN   B OD1 1 ? 
ATOM   2856 N ND2 . ASN   B 1 63  ? 28.727  -30.353 55.402 1.000 21.610 0 63  ASN   B ND2 1 ? 
ATOM   2857 N N   . HIS   B 1 64  ? 32.306  -26.963 53.285 1.000 21.503 0 64  HIS   B N   1 ? 
ATOM   2858 C CA  . HIS   B 1 64  ? 32.995  -25.684 53.218 1.000 21.376 0 64  HIS   B CA  1 ? 
ATOM   2859 C C   . HIS   B 1 64  ? 33.525  -25.357 51.815 1.000 21.411 0 64  HIS   B C   1 ? 
ATOM   2860 O O   . HIS   B 1 64  ? 33.807  -24.190 51.524 1.000 23.108 0 64  HIS   B O   1 ? 
ATOM   2861 C CB  . HIS   B 1 64  ? 34.138  -25.665 54.242 1.000 21.521 0 64  HIS   B CB  1 ? 
ATOM   2862 C CG  . HIS   B 1 64  ? 34.818  -24.349 54.392 1.000 20.764 0 64  HIS   B CG  1 ? 
ATOM   2863 N ND1 . HIS   B 1 64  ? 34.361  -23.362 55.253 1.000 23.866 0 64  HIS   B ND1 1 ? 
ATOM   2864 C CD2 . HIS   B 1 64  ? 35.933  -23.874 53.835 1.000 20.465 0 64  HIS   B CD2 1 ? 
ATOM   2865 C CE1 . HIS   B 1 64  ? 35.183  -22.313 55.205 1.000 21.547 0 64  HIS   B CE1 1 ? 
ATOM   2866 N NE2 . HIS   B 1 64  ? 36.149  -22.601 54.352 1.000 21.376 0 64  HIS   B NE2 1 ? 
ATOM   2867 N N   . ASN   B 1 65  ? 33.691  -26.365 50.947 1.000 20.729 0 65  ASN   B N   1 ? 
ATOM   2868 C CA  . ASN   B 1 65  ? 34.172  -26.132 49.589 1.000 21.147 0 65  ASN   B CA  1 ? 
ATOM   2869 C C   . ASN   B 1 65  ? 33.110  -25.402 48.746 1.000 21.180 0 65  ASN   B C   1 ? 
ATOM   2870 O O   . ASN   B 1 65  ? 33.421  -24.859 47.684 1.000 21.100 0 65  ASN   B O   1 ? 
ATOM   2871 C CB  . ASN   B 1 65  ? 34.578  -27.429 48.872 1.000 21.095 0 65  ASN   B CB  1 ? 
ATOM   2872 C CG  . ASN   B 1 65  ? 35.747  -28.190 49.475 1.000 22.540 0 65  ASN   B CG  1 ? 
ATOM   2873 O OD1 . ASN   B 1 65  ? 35.865  -29.403 49.287 1.000 22.979 0 65  ASN   B OD1 1 ? 
ATOM   2874 N ND2 . ASN   B 1 65  ? 36.642  -27.513 50.167 1.000 22.244 0 65  ASN   B ND2 1 ? 
ATOM   2875 N N   . PHE   B 1 66  ? 31.859  -25.346 49.209 1.000 20.686 0 66  PHE   B N   1 ? 
ATOM   2876 C CA  . PHE   B 1 66  ? 30.787  -24.793 48.392 1.000 21.090 0 66  PHE   B CA  1 ? 
ATOM   2877 C C   . PHE   B 1 66  ? 30.434  -23.376 48.845 1.000 22.563 0 66  PHE   B C   1 ? 
ATOM   2878 O O   . PHE   B 1 66  ? 29.733  -23.200 49.842 1.000 27.902 0 66  PHE   B O   1 ? 
ATOM   2879 C CB  . PHE   B 1 66  ? 29.555  -25.689 48.474 1.000 20.484 0 66  PHE   B CB  1 ? 
ATOM   2880 C CG  . PHE   B 1 66  ? 29.742  -27.067 47.905 1.000 20.455 0 66  PHE   B CG  1 ? 
ATOM   2881 C CD1 . PHE   B 1 66  ? 29.676  -27.286 46.542 1.000 19.434 0 66  PHE   B CD1 1 ? 
ATOM   2882 C CD2 . PHE   B 1 66  ? 29.992  -28.146 48.737 1.000 23.156 0 66  PHE   B CD2 1 ? 
ATOM   2883 C CE1 . PHE   B 1 66  ? 29.814  -28.566 46.033 1.000 20.710 0 66  PHE   B CE1 1 ? 
ATOM   2884 C CE2 . PHE   B 1 66  ? 30.166  -29.427 48.217 1.000 23.502 0 66  PHE   B CE2 1 ? 
ATOM   2885 C CZ  . PHE   B 1 66  ? 30.083  -29.631 46.862 1.000 21.841 0 66  PHE   B CZ  1 ? 
ATOM   2886 N N   . LEU   B 1 67  ? 30.858  -22.374 48.069 1.000 20.316 0 67  LEU   B N   1 ? 
ATOM   2887 C CA  . LEU   B 1 67  ? 30.482  -20.996 48.328 1.000 21.515 0 67  LEU   B CA  1 ? 
ATOM   2888 C C   . LEU   B 1 67  ? 29.178  -20.708 47.599 1.000 21.839 0 67  LEU   B C   1 ? 
ATOM   2889 O O   . LEU   B 1 67  ? 29.140  -20.716 46.370 1.000 23.703 0 67  LEU   B O   1 ? 
ATOM   2890 C CB  . LEU   B 1 67  ? 31.605  -20.049 47.875 1.000 23.999 0 67  LEU   B CB  1 ? 
ATOM   2891 C CG  . LEU   B 1 67  ? 31.337  -18.545 48.004 1.000 25.685 0 67  LEU   B CG  1 ? 
ATOM   2892 C CD1 . LEU   B 1 67  ? 30.916  -18.168 49.420 1.000 26.078 0 67  LEU   B CD1 1 ? 
ATOM   2893 C CD2 . LEU   B 1 67  ? 32.584  -17.752 47.614 1.000 29.955 0 67  LEU   B CD2 1 ? 
ATOM   2894 N N   . VAL   B 1 68  ? 28.109  -20.504 48.382 1.000 21.252 0 68  VAL   B N   1 ? 
ATOM   2895 C CA  . VAL   B 1 68  ? 26.810  -20.179 47.838 1.000 20.691 0 68  VAL   B CA  1 ? 
ATOM   2896 C C   . VAL   B 1 68  ? 26.495  -18.743 48.240 1.000 21.331 0 68  VAL   B C   1 ? 
ATOM   2897 O O   . VAL   B 1 68  ? 26.525  -18.419 49.435 1.000 22.276 0 68  VAL   B O   1 ? 
ATOM   2898 C CB  . VAL   B 1 68  ? 25.729  -21.158 48.336 1.000 21.025 0 68  VAL   B CB  1 ? 
ATOM   2899 C CG1 . VAL   B 1 68  ? 24.374  -20.833 47.717 1.000 19.792 0 68  VAL   B CG1 1 ? 
ATOM   2900 C CG2 . VAL   B 1 68  ? 26.098  -22.611 48.085 1.000 20.207 0 68  VAL   B CG2 1 ? 
ATOM   2901 N N   . GLN   B 1 69  ? 26.210  -17.895 47.248 1.000 20.806 0 69  GLN   B N   1 ? 
ATOM   2902 C CA  . GLN   B 1 69  ? 25.958  -16.481 47.491 1.000 23.161 0 69  GLN   B CA  1 ? 
ATOM   2903 C C   . GLN   B 1 69  ? 24.599  -16.130 46.909 1.000 22.896 0 69  GLN   B C   1 ? 
ATOM   2904 O O   . GLN   B 1 69  ? 24.335  -16.466 45.757 1.000 20.395 0 69  GLN   B O   1 ? 
ATOM   2905 C CB  . GLN   B 1 69  ? 27.075  -15.633 46.883 1.000 28.732 0 69  GLN   B CB  1 ? 
ATOM   2906 C CG  . GLN   B 1 69  ? 27.687  -14.630 47.854 1.000 38.097 0 69  GLN   B CG  1 ? 
ATOM   2907 C CD  . GLN   B 1 69  ? 29.183  -14.499 47.664 1.000 45.990 0 69  GLN   B CD  1 ? 
ATOM   2908 O OE1 . GLN   B 1 69  ? 29.767  -15.003 46.701 1.000 45.544 0 69  GLN   B OE1 1 ? 
ATOM   2909 N NE2 . GLN   B 1 69  ? 29.822  -13.819 48.603 1.000 50.165 0 69  GLN   B NE2 1 ? 
ATOM   2910 N N   . ALA   B 1 70  ? 23.759  -15.496 47.742 1.000 23.463 0 70  ALA   B N   1 ? 
ATOM   2911 C CA  . ALA   B 1 70  ? 22.439  -14.996 47.386 1.000 24.627 0 70  ALA   B CA  1 ? 
ATOM   2912 C C   . ALA   B 1 70  ? 22.407  -13.491 47.633 1.000 28.456 0 70  ALA   B C   1 ? 
ATOM   2913 O O   . ALA   B 1 70  ? 22.211  -13.053 48.760 1.000 31.502 0 70  ALA   B O   1 ? 
ATOM   2914 C CB  . ALA   B 1 70  ? 21.380  -15.686 48.212 1.000 22.549 0 70  ALA   B CB  1 ? 
ATOM   2915 N N   . GLY   B 1 71  ? 22.658  -12.700 46.593 1.000 33.900 0 71  GLY   B N   1 ? 
ATOM   2916 C CA  . GLY   B 1 71  ? 22.868  -11.275 46.799 1.000 37.160 0 71  GLY   B CA  1 ? 
ATOM   2917 C C   . GLY   B 1 71  ? 24.183  -11.028 47.528 1.000 38.269 0 71  GLY   B C   1 ? 
ATOM   2918 O O   . GLY   B 1 71  ? 25.211  -11.532 47.099 1.000 37.862 0 71  GLY   B O   1 ? 
ATOM   2919 N N   . ASN   B 1 72  ? 24.126  -10.309 48.656 1.000 44.488 0 72  ASN   B N   1 ? 
ATOM   2920 C CA  . ASN   B 1 72  ? 25.315  -9.945  49.418 1.000 49.971 0 72  ASN   B CA  1 ? 
ATOM   2921 C C   . ASN   B 1 72  ? 25.562  -10.939 50.554 1.000 45.432 0 72  ASN   B C   1 ? 
ATOM   2922 O O   . ASN   B 1 72  ? 26.385  -10.692 51.431 1.000 45.807 0 72  ASN   B O   1 ? 
ATOM   2923 C CB  . ASN   B 1 72  ? 25.169  -8.532  49.990 1.000 58.759 0 72  ASN   B CB  1 ? 
ATOM   2924 C CG  . ASN   B 1 72  ? 24.911  -7.494  48.917 1.000 62.495 0 72  ASN   B CG  1 ? 
ATOM   2925 O OD1 . ASN   B 1 72  ? 25.843  -7.032  48.264 1.000 60.881 0 72  ASN   B OD1 1 ? 
ATOM   2926 N ND2 . ASN   B 1 72  ? 23.655  -7.115  48.736 1.000 63.554 0 72  ASN   B ND2 1 ? 
ATOM   2927 N N   . VAL   B 1 73  ? 24.875  -12.082 50.503 1.000 40.598 0 73  VAL   B N   1 ? 
ATOM   2928 C CA  . VAL   B 1 73  ? 24.746  -12.971 51.640 1.000 39.334 0 73  VAL   B CA  1 ? 
ATOM   2929 C C   . VAL   B 1 73  ? 25.298  -14.349 51.270 1.000 35.926 0 73  VAL   B C   1 ? 
ATOM   2930 O O   . VAL   B 1 73  ? 24.847  -14.960 50.300 1.000 28.227 0 73  VAL   B O   1 ? 
ATOM   2931 C CB  . VAL   B 1 73  ? 23.260  -13.037 52.024 1.000 40.350 0 73  VAL   B CB  1 ? 
ATOM   2932 C CG1 . VAL   B 1 73  ? 23.006  -13.847 53.281 1.000 40.984 0 73  VAL   B CG1 1 ? 
ATOM   2933 C CG2 . VAL   B 1 73  ? 22.676  -11.640 52.149 1.000 43.970 0 73  VAL   B CG2 1 ? 
ATOM   2934 N N   . GLN   B 1 74  ? 26.263  -14.837 52.063 1.000 34.085 0 74  GLN   B N   1 ? 
ATOM   2935 C CA  . GLN   B 1 74  ? 26.721  -16.210 51.956 1.000 33.514 0 74  GLN   B CA  1 ? 
ATOM   2936 C C   . GLN   B 1 74  ? 25.734  -17.102 52.690 1.000 30.874 0 74  GLN   B C   1 ? 
ATOM   2937 O O   . GLN   B 1 74  ? 25.303  -16.747 53.777 1.000 31.096 0 74  GLN   B O   1 ? 
ATOM   2938 C CB  . GLN   B 1 74  ? 28.108  -16.393 52.556 1.000 39.375 0 74  GLN   B CB  1 ? 
ATOM   2939 C CG  . GLN   B 1 74  ? 29.118  -15.384 52.027 1.000 52.257 0 74  GLN   B CG  1 ? 
ATOM   2940 C CD  . GLN   B 1 74  ? 30.552  -15.817 52.231 1.000 53.022 0 74  GLN   B CD  1 ? 
ATOM   2941 O OE1 . GLN   B 1 74  ? 31.486  -15.051 51.970 1.000 54.811 0 74  GLN   B OE1 1 ? 
ATOM   2942 N NE2 . GLN   B 1 74  ? 30.725  -17.048 52.698 1.000 43.636 0 74  GLN   B NE2 1 ? 
ATOM   2943 N N   . LEU   B 1 75  ? 25.339  -18.216 52.064 1.000 28.815 0 75  LEU   B N   1 ? 
ATOM   2944 C CA  . LEU   B 1 75  ? 24.554  -19.244 52.732 1.000 28.028 0 75  LEU   B CA  1 ? 
ATOM   2945 C C   . LEU   B 1 75  ? 25.507  -20.335 53.194 1.000 26.860 0 75  LEU   B C   1 ? 
ATOM   2946 O O   . LEU   B 1 75  ? 26.328  -20.804 52.400 1.000 30.602 0 75  LEU   B O   1 ? 
ATOM   2947 C CB  . LEU   B 1 75  ? 23.529  -19.856 51.773 1.000 25.992 0 75  LEU   B CB  1 ? 
ATOM   2948 C CG  . LEU   B 1 75  ? 22.531  -18.896 51.138 1.000 28.632 0 75  LEU   B CG  1 ? 
ATOM   2949 C CD1 . LEU   B 1 75  ? 21.504  -19.672 50.323 1.000 30.108 0 75  LEU   B CD1 1 ? 
ATOM   2950 C CD2 . LEU   B 1 75  ? 21.832  -18.051 52.195 1.000 32.741 0 75  LEU   B CD2 1 ? 
ATOM   2951 N N   . ARG   B 1 76  ? 25.345  -20.764 54.446 1.000 25.432 0 76  ARG   B N   1 ? 
ATOM   2952 C CA  . ARG   B 1 76  ? 26.152  -21.837 55.001 1.000 28.712 0 76  ARG   B CA  1 ? 
ATOM   2953 C C   . ARG   B 1 76  ? 25.604  -23.182 54.516 1.000 24.564 0 76  ARG   B C   1 ? 
ATOM   2954 O O   . ARG   B 1 76  ? 24.431  -23.504 54.725 1.000 21.681 0 76  ARG   B O   1 ? 
ATOM   2955 C CB  . ARG   B 1 76  ? 26.174  -21.740 56.530 1.000 35.314 0 76  ARG   B CB  1 ? 
ATOM   2956 C CG  . ARG   B 1 76  ? 26.885  -22.901 57.213 1.000 43.794 0 76  ARG   B CG  1 ? 
ATOM   2957 C CD  . ARG   B 1 76  ? 26.240  -23.283 58.541 1.000 51.003 0 76  ARG   B CD  1 ? 
ATOM   2958 N NE  . ARG   B 1 76  ? 26.329  -22.215 59.522 1.000 55.858 0 76  ARG   B NE  1 ? 
ATOM   2959 C CZ  . ARG   B 1 76  ? 27.468  -21.781 60.053 1.000 68.882 0 76  ARG   B CZ  1 ? 
ATOM   2960 N NH1 . ARG   B 1 76  ? 28.601  -22.431 59.833 1.000 71.979 0 76  ARG   B NH1 1 ? 
ATOM   2961 N NH2 . ARG   B 1 76  ? 27.469  -20.711 60.829 1.000 72.417 0 76  ARG   B NH2 1 ? 
ATOM   2962 N N   . VAL   B 1 77  ? 26.495  -23.966 53.896 1.000 21.475 0 77  VAL   B N   1 ? 
ATOM   2963 C CA  . VAL   B 1 77  ? 26.197  -25.315 53.465 1.000 21.508 0 77  VAL   B CA  1 ? 
ATOM   2964 C C   . VAL   B 1 77  ? 26.443  -26.276 54.628 1.000 24.123 0 77  VAL   B C   1 ? 
ATOM   2965 O O   . VAL   B 1 77  ? 27.521  -26.282 55.218 1.000 22.915 0 77  VAL   B O   1 ? 
ATOM   2966 C CB  . VAL   B 1 77  ? 27.040  -25.678 52.234 1.000 19.864 0 77  VAL   B CB  1 ? 
ATOM   2967 C CG1 . VAL   B 1 77  ? 26.758  -27.089 51.728 1.000 19.205 0 77  VAL   B CG1 1 ? 
ATOM   2968 C CG2 . VAL   B 1 77  ? 26.802  -24.667 51.135 1.000 20.878 0 77  VAL   B CG2 1 ? 
ATOM   2969 N N   . ILE   B 1 78  ? 25.419  -27.079 54.926 1.000 24.184 0 78  ILE   B N   1 ? 
ATOM   2970 C CA  . ILE   B 1 78  ? 25.448  -28.013 56.031 1.000 25.435 0 78  ILE   B CA  1 ? 
ATOM   2971 C C   . ILE   B 1 78  ? 25.235  -29.443 55.550 1.000 26.217 0 78  ILE   B C   1 ? 
ATOM   2972 O O   . ILE   B 1 78  ? 25.266  -30.365 56.351 1.000 27.662 0 78  ILE   B O   1 ? 
ATOM   2973 C CB  . ILE   B 1 78  ? 24.409  -27.607 57.083 1.000 26.529 0 78  ILE   B CB  1 ? 
ATOM   2974 C CG1 . ILE   B 1 78  ? 22.984  -27.682 56.529 1.000 27.009 0 78  ILE   B CG1 1 ? 
ATOM   2975 C CG2 . ILE   B 1 78  ? 24.757  -26.230 57.647 1.000 25.843 0 78  ILE   B CG2 1 ? 
ATOM   2976 C CD1 . ILE   B 1 78  ? 21.924  -27.650 57.607 1.000 27.352 0 78  ILE   B CD1 1 ? 
ATOM   2977 N N   . GLY   B 1 79  ? 25.089  -29.657 54.239 1.000 25.415 0 79  GLY   B N   1 ? 
ATOM   2978 C CA  . GLY   B 1 79  ? 25.050  -31.023 53.742 1.000 24.449 0 79  GLY   B CA  1 ? 
ATOM   2979 C C   . GLY   B 1 79  ? 25.094  -31.035 52.223 1.000 25.482 0 79  GLY   B C   1 ? 
ATOM   2980 O O   . GLY   B 1 79  ? 24.837  -30.021 51.582 1.000 25.586 0 79  GLY   B O   1 ? 
ATOM   2981 N N   . HIS   B 1 80  ? 25.428  -32.186 51.660 1.000 25.838 0 80  HIS   B N   1 ? 
ATOM   2982 C CA  . HIS   B 1 80  ? 25.475  -32.315 50.218 1.000 27.341 0 80  HIS   B CA  1 ? 
ATOM   2983 C C   . HIS   B 1 80  ? 25.112  -33.738 49.835 1.000 27.603 0 80  HIS   B C   1 ? 
ATOM   2984 O O   . HIS   B 1 80  ? 25.359  -34.677 50.585 1.000 29.678 0 80  HIS   B O   1 ? 
ATOM   2985 C CB  . HIS   B 1 80  ? 26.830  -31.905 49.628 1.000 27.359 0 80  HIS   B CB  1 ? 
ATOM   2986 C CG  . HIS   B 1 80  ? 28.052  -32.502 50.232 1.000 31.023 0 80  HIS   B CG  1 ? 
ATOM   2987 N ND1 . HIS   B 1 80  ? 28.628  -32.021 51.391 1.000 30.611 0 80  HIS   B ND1 1 ? 
ATOM   2988 C CD2 . HIS   B 1 80  ? 28.855  -33.500 49.801 1.000 33.086 0 80  HIS   B CD2 1 ? 
ATOM   2989 C CE1 . HIS   B 1 80  ? 29.734  -32.718 51.642 1.000 34.502 0 80  HIS   B CE1 1 ? 
ATOM   2990 N NE2 . HIS   B 1 80  ? 29.889  -33.623 50.694 1.000 33.605 0 80  HIS   B NE2 1 ? 
ATOM   2991 N N   . SER   B 1 81  ? 24.501  -33.861 48.665 1.000 23.933 0 81  SER   B N   1 ? 
ATOM   2992 C CA  . SER   B 1 81  ? 24.149  -35.153 48.120 1.000 25.718 0 81  SER   B CA  1 ? 
ATOM   2993 C C   . SER   B 1 81  ? 23.889  -34.966 46.632 1.000 25.802 0 81  SER   B C   1 ? 
ATOM   2994 O O   . SER   B 1 81  ? 23.768  -33.842 46.162 1.000 27.148 0 81  SER   B O   1 ? 
ATOM   2995 C CB  . SER   B 1 81  ? 22.954  -35.751 48.813 1.000 23.999 0 81  SER   B CB  1 ? 
ATOM   2996 O OG  . SER   B 1 81  ? 21.766  -35.065 48.459 1.000 23.810 0 81  SER   B OG  1 ? 
ATOM   2997 N N   . MET   B 1 82  ? 23.763  -36.082 45.923 1.000 25.744 0 82  MET   B N   1 ? 
ATOM   2998 C CA  . MET   B 1 82  ? 23.662  -36.082 44.482 1.000 26.041 0 82  MET   B CA  1 ? 
ATOM   2999 C C   . MET   B 1 82  ? 22.468  -36.937 44.083 1.000 26.181 0 82  MET   B C   1 ? 
ATOM   3000 O O   . MET   B 1 82  ? 22.239  -38.006 44.664 1.000 23.738 0 82  MET   B O   1 ? 
ATOM   3001 C CB  . MET   B 1 82  ? 24.963  -36.665 43.945 1.000 28.351 0 82  MET   B CB  1 ? 
ATOM   3002 C CG  . MET   B 1 82  ? 25.046  -36.841 42.463 1.000 30.700 0 82  MET   B CG  1 ? 
ATOM   3003 S SD  . MET   B 1 82  ? 26.804  -36.972 42.055 1.000 32.792 0 82  MET   B SD  1 ? 
ATOM   3004 C CE  . MET   B 1 82  ? 27.197  -38.551 42.811 1.000 34.086 0 82  MET   B CE  1 ? 
ATOM   3005 N N   . GLN   B 1 83  ? 21.663  -36.402 43.163 1.000 21.524 0 83  GLN   B N   1 ? 
ATOM   3006 C CA  . GLN   B 1 83  ? 20.604  -37.168 42.541 1.000 21.759 0 83  GLN   B CA  1 ? 
ATOM   3007 C C   . GLN   B 1 83  ? 20.804  -37.103 41.027 1.000 20.022 0 83  GLN   B C   1 ? 
ATOM   3008 O O   . GLN   B 1 83  ? 20.644  -36.044 40.423 1.000 18.471 0 83  GLN   B O   1 ? 
ATOM   3009 C CB  . GLN   B 1 83  ? 19.248  -36.627 42.985 1.000 22.923 0 83  GLN   B CB  1 ? 
ATOM   3010 C CG  . GLN   B 1 83  ? 18.081  -37.332 42.317 1.000 25.262 0 83  GLN   B CG  1 ? 
ATOM   3011 C CD  . GLN   B 1 83  ? 16.755  -36.759 42.757 1.000 28.344 0 83  GLN   B CD  1 ? 
ATOM   3012 O OE1 . GLN   B 1 83  ? 16.679  -35.713 43.401 1.000 32.527 0 83  GLN   B OE1 1 ? 
ATOM   3013 N NE2 . GLN   B 1 83  ? 15.695  -37.475 42.446 1.000 27.133 0 83  GLN   B NE2 1 ? 
ATOM   3014 N N   . ASN   B 1 84  ? 21.216  -38.230 40.442 1.000 18.121 0 84  ASN   B N   1 ? 
ATOM   3015 C CA  . ASN   B 1 84  ? 21.552  -38.302 39.033 1.000 18.795 0 84  ASN   B CA  1 ? 
ATOM   3016 C C   . ASN   B 1 84  ? 22.624  -37.239 38.740 1.000 19.261 0 84  ASN   B C   1 ? 
ATOM   3017 O O   . ASN   B 1 84  ? 23.671  -37.231 39.389 1.000 19.865 0 84  ASN   B O   1 ? 
ATOM   3018 C CB  . ASN   B 1 84  ? 20.243  -38.286 38.235 1.000 18.427 0 84  ASN   B CB  1 ? 
ATOM   3019 C CG  . ASN   B 1 84  ? 19.344  -39.460 38.603 1.000 18.270 0 84  ASN   B CG  1 ? 
ATOM   3020 O OD1 . ASN   B 1 84  ? 19.732  -40.623 38.500 1.000 16.348 0 84  ASN   B OD1 1 ? 
ATOM   3021 N ND2 . ASN   B 1 84  ? 18.140  -39.179 39.054 1.000 18.223 0 84  ASN   B ND2 1 ? 
ATOM   3022 N N   . CYS   B 1 85  ? 22.350  -36.289 37.827 1.000 17.535 0 85  CYS   B N   1 ? 
ATOM   3023 C CA  . CYS   B 1 85  ? 23.329  -35.288 37.431 1.000 16.542 0 85  CYS   B CA  1 ? 
ATOM   3024 C C   . CYS   B 1 85  ? 23.192  -33.963 38.197 1.000 16.393 0 85  CYS   B C   1 ? 
ATOM   3025 O O   . CYS   B 1 85  ? 23.870  -32.985 37.862 1.000 15.242 0 85  CYS   B O   1 ? 
ATOM   3026 C CB  . CYS   B 1 85  ? 23.244  -35.057 35.928 1.000 17.553 0 85  CYS   B CB  1 ? 
ATOM   3027 S SG  . CYS   B 1 85  ? 23.546  -36.559 34.952 1.000 22.160 0 85  CYS   B SG  1 ? 
ATOM   3028 N N   . VAL   B 1 86  ? 22.331  -33.912 39.223 1.000 16.652 0 86  VAL   B N   1 ? 
ATOM   3029 C CA  . VAL   B 1 86  ? 22.154  -32.698 39.988 1.000 18.634 0 86  VAL   B CA  1 ? 
ATOM   3030 C C   . VAL   B 1 86  ? 22.727  -32.869 41.386 1.000 19.068 0 86  VAL   B C   1 ? 
ATOM   3031 O O   . VAL   B 1 86  ? 22.663  -33.912 42.006 1.000 18.964 0 86  VAL   B O   1 ? 
ATOM   3032 C CB  . VAL   B 1 86  ? 20.709  -32.197 40.047 1.000 21.475 0 86  VAL   B CB  1 ? 
ATOM   3033 C CG1 . VAL   B 1 86  ? 20.273  -31.671 38.687 1.000 23.261 0 86  VAL   B CG1 1 ? 
ATOM   3034 C CG2 . VAL   B 1 86  ? 19.748  -33.244 40.561 1.000 24.947 0 86  VAL   B CG2 1 ? 
ATOM   3035 N N   . LEU   B 1 87  ? 23.344  -31.796 41.844 1.000 19.024 0 87  LEU   B N   1 ? 
ATOM   3036 C CA  . LEU   B 1 87  ? 23.863  -31.728 43.186 1.000 18.310 0 87  LEU   B CA  1 ? 
ATOM   3037 C C   . LEU   B 1 87  ? 22.821  -30.992 44.027 1.000 17.662 0 87  LEU   B C   1 ? 
ATOM   3038 O O   . LEU   B 1 87  ? 22.215  -30.040 43.545 1.000 15.616 0 87  LEU   B O   1 ? 
ATOM   3039 C CB  . LEU   B 1 87  ? 25.214  -31.031 43.049 1.000 19.165 0 87  LEU   B CB  1 ? 
ATOM   3040 C CG  . LEU   B 1 87  ? 26.000  -30.795 44.330 1.000 21.079 0 87  LEU   B CG  1 ? 
ATOM   3041 C CD1 . LEU   B 1 87  ? 26.563  -32.102 44.856 1.000 23.977 0 87  LEU   B CD1 1 ? 
ATOM   3042 C CD2 . LEU   B 1 87  ? 27.109  -29.805 44.082 1.000 21.730 0 87  LEU   B CD2 1 ? 
ATOM   3043 N N   . LYS   B 1 88  ? 22.522  -31.525 45.219 1.000 18.359 0 88  LYS   B N   1 ? 
ATOM   3044 C CA  . LYS   B 1 88  ? 21.672  -30.858 46.190 1.000 20.387 0 88  LYS   B CA  1 ? 
ATOM   3045 C C   . LYS   B 1 88  ? 22.538  -30.402 47.363 1.000 19.267 0 88  LYS   B C   1 ? 
ATOM   3046 O O   . LYS   B 1 88  ? 23.177  -31.209 48.032 1.000 19.618 0 88  LYS   B O   1 ? 
ATOM   3047 C CB  . LYS   B 1 88  ? 20.515  -31.793 46.556 1.000 23.364 0 88  LYS   B CB  1 ? 
ATOM   3048 C CG  . LYS   B 1 88  ? 19.756  -32.277 45.324 1.000 26.680 0 88  LYS   B CG  1 ? 
ATOM   3049 C CD  . LYS   B 1 88  ? 18.425  -32.961 45.585 1.000 30.698 0 88  LYS   B CD  1 ? 
ATOM   3050 C CE  . LYS   B 1 88  ? 18.574  -34.262 46.335 1.000 36.268 0 88  LYS   B CE  1 ? 
ATOM   3051 N NZ  . LYS   B 1 88  ? 17.392  -35.131 46.135 1.000 39.851 0 88  LYS   B NZ  1 ? 
ATOM   3052 N N   . LEU   B 1 89  ? 22.609  -29.088 47.572 1.000 17.800 0 89  LEU   B N   1 ? 
ATOM   3053 C CA  . LEU   B 1 89  ? 23.286  -28.557 48.736 1.000 20.238 0 89  LEU   B CA  1 ? 
ATOM   3054 C C   . LEU   B 1 89  ? 22.228  -28.165 49.768 1.000 22.336 0 89  LEU   B C   1 ? 
ATOM   3055 O O   . LEU   B 1 89  ? 21.407  -27.297 49.502 1.000 23.510 0 89  LEU   B O   1 ? 
ATOM   3056 C CB  . LEU   B 1 89  ? 24.131  -27.343 48.343 1.000 18.548 0 89  LEU   B CB  1 ? 
ATOM   3057 C CG  . LEU   B 1 89  ? 25.181  -27.577 47.259 1.000 16.604 0 89  LEU   B CG  1 ? 
ATOM   3058 C CD1 . LEU   B 1 89  ? 25.854  -26.276 46.906 1.000 16.265 0 89  LEU   B CD1 1 ? 
ATOM   3059 C CD2 . LEU   B 1 89  ? 26.206  -28.579 47.729 1.000 18.316 0 89  LEU   B CD2 1 ? 
ATOM   3060 N N   . LYS   B 1 90  ? 22.275  -28.790 50.948 1.000 21.066 0 90  LYS   B N   1 ? 
ATOM   3061 C CA  . LYS   B 1 90  ? 21.453  -28.352 52.056 1.000 22.839 0 90  LYS   B CA  1 ? 
ATOM   3062 C C   . LYS   B 1 90  ? 22.131  -27.146 52.686 1.000 21.231 0 90  LYS   B C   1 ? 
ATOM   3063 O O   . LYS   B 1 90  ? 23.336  -27.174 52.935 1.000 18.824 0 90  LYS   B O   1 ? 
ATOM   3064 C CB  . LYS   B 1 90  ? 21.285  -29.443 53.121 1.000 26.884 0 90  LYS   B CB  1 ? 
ATOM   3065 C CG  . LYS   B 1 90  ? 20.264  -29.098 54.200 1.000 31.431 0 90  LYS   B CG  1 ? 
ATOM   3066 C CD  . LYS   B 1 90  ? 19.036  -29.971 54.221 1.000 40.296 0 90  LYS   B CD  1 ? 
ATOM   3067 C CE  . LYS   B 1 90  ? 19.329  -31.266 54.952 1.000 48.386 0 90  LYS   B CE  1 ? 
ATOM   3068 N NZ  . LYS   B 1 90  ? 18.186  -32.207 54.915 1.000 51.970 0 90  LYS   B NZ  1 ? 
ATOM   3069 N N   . VAL   B 1 91  ? 21.353  -26.083 52.913 1.000 22.147 0 91  VAL   B N   1 ? 
ATOM   3070 C CA  . VAL   B 1 91  ? 21.878  -24.868 53.525 1.000 23.449 0 91  VAL   B CA  1 ? 
ATOM   3071 C C   . VAL   B 1 91  ? 21.080  -24.603 54.795 1.000 23.759 0 91  VAL   B C   1 ? 
ATOM   3072 O O   . VAL   B 1 91  ? 20.006  -25.147 54.942 1.000 21.400 0 91  VAL   B O   1 ? 
ATOM   3073 C CB  . VAL   B 1 91  ? 21.807  -23.677 52.553 1.000 25.021 0 91  VAL   B CB  1 ? 
ATOM   3074 C CG1 . VAL   B 1 91  ? 22.708  -23.899 51.345 1.000 23.958 0 91  VAL   B CG1 1 ? 
ATOM   3075 C CG2 . VAL   B 1 91  ? 20.365  -23.401 52.122 1.000 24.891 0 91  VAL   B CG2 1 ? 
ATOM   3076 N N   . ASP   B 1 92  ? 21.581  -23.738 55.682 1.000 29.004 0 92  ASP   B N   1 ? 
ATOM   3077 C CA  . ASP   B 1 92  ? 20.983  -23.593 57.004 1.000 31.880 0 92  ASP   B CA  1 ? 
ATOM   3078 C C   . ASP   B 1 92  ? 19.803  -22.616 56.982 1.000 33.729 0 92  ASP   B C   1 ? 
ATOM   3079 O O   . ASP   B 1 92  ? 19.186  -22.391 58.015 1.000 32.575 0 92  ASP   B O   1 ? 
ATOM   3080 C CB  . ASP   B 1 92  ? 22.032  -23.223 58.061 1.000 32.237 0 92  ASP   B CB  1 ? 
ATOM   3081 C CG  . ASP   B 1 92  ? 22.587  -21.810 57.987 1.000 35.461 0 92  ASP   B CG  1 ? 
ATOM   3082 O OD1 . ASP   B 1 92  ? 22.042  -20.982 57.220 1.000 38.625 0 92  ASP   B OD1 1 ? 
ATOM   3083 O OD2 . ASP   B 1 92  ? 23.558  -21.535 58.727 1.000 37.365 0 92  ASP   B OD2 1 ? 
ATOM   3084 N N   . THR   B 1 93  ? 19.450  -22.070 55.811 1.000 32.709 0 93  THR   B N   1 ? 
ATOM   3085 C CA  . THR   B 1 93  ? 18.371  -21.098 55.724 1.000 30.554 0 93  THR   B CA  1 ? 
ATOM   3086 C C   . THR   B 1 93  ? 17.455  -21.449 54.557 1.000 29.819 0 93  THR   B C   1 ? 
ATOM   3087 O O   . THR   B 1 93  ? 17.918  -21.701 53.441 1.000 25.808 0 93  THR   B O   1 ? 
ATOM   3088 C CB  . THR   B 1 93  ? 18.908  -19.678 55.511 1.000 34.629 0 93  THR   B CB  1 ? 
ATOM   3089 O OG1 . THR   B 1 93  ? 19.866  -19.422 56.534 1.000 36.657 0 93  THR   B OG1 1 ? 
ATOM   3090 C CG2 . THR   B 1 93  ? 17.832  -18.613 55.555 1.000 35.552 0 93  THR   B CG2 1 ? 
ATOM   3091 N N   . ALA   B 1 94  ? 16.151  -21.456 54.848 1.000 25.289 0 94  ALA   B N   1 ? 
ATOM   3092 C CA  . ALA   B 1 94  ? 15.128  -21.645 53.842 1.000 24.038 0 94  ALA   B CA  1 ? 
ATOM   3093 C C   . ALA   B 1 94  ? 14.977  -20.361 53.035 1.000 23.979 0 94  ALA   B C   1 ? 
ATOM   3094 O O   . ALA   B 1 94  ? 15.071  -19.256 53.576 1.000 23.521 0 94  ALA   B O   1 ? 
ATOM   3095 C CB  . ALA   B 1 94  ? 13.827  -22.038 54.492 1.000 23.198 0 94  ALA   B CB  1 ? 
ATOM   3096 N N   . ASN   B 1 95  ? 14.777  -20.512 51.721 1.000 23.151 0 95  ASN   B N   1 ? 
ATOM   3097 C CA  . ASN   B 1 95  ? 14.620  -19.346 50.867 1.000 20.107 0 95  ASN   B CA  1 ? 
ATOM   3098 C C   . ASN   B 1 95  ? 13.271  -18.714 51.207 1.000 19.164 0 95  ASN   B C   1 ? 
ATOM   3099 O O   . ASN   B 1 95  ? 12.218  -19.295 50.913 1.000 15.769 0 95  ASN   B O   1 ? 
ATOM   3100 C CB  . ASN   B 1 95  ? 14.727  -19.697 49.378 1.000 21.268 0 95  ASN   B CB  1 ? 
ATOM   3101 C CG  . ASN   B 1 95  ? 14.680  -18.464 48.492 1.000 20.446 0 95  ASN   B CG  1 ? 
ATOM   3102 O OD1 . ASN   B 1 95  ? 14.549  -17.351 48.990 1.000 19.169 0 95  ASN   B OD1 1 ? 
ATOM   3103 N ND2 . ASN   B 1 95  ? 14.814  -18.648 47.188 1.000 20.740 0 95  ASN   B ND2 1 ? 
ATOM   3104 N N   . PRO   B 1 96  ? 13.258  -17.517 51.830 1.000 19.463 0 96  PRO   B N   1 ? 
ATOM   3105 C CA  . PRO   B 1 96  ? 12.001  -16.843 52.123 1.000 22.129 0 96  PRO   B CA  1 ? 
ATOM   3106 C C   . PRO   B 1 96  ? 11.175  -16.524 50.869 1.000 22.672 0 96  PRO   B C   1 ? 
ATOM   3107 O O   . PRO   B 1 96  ? 9.960   -16.394 50.949 1.000 22.799 0 96  PRO   B O   1 ? 
ATOM   3108 C CB  . PRO   B 1 96  ? 12.447  -15.564 52.876 1.000 23.614 0 96  PRO   B CB  1 ? 
ATOM   3109 C CG  . PRO   B 1 96  ? 13.886  -15.331 52.411 1.000 22.627 0 96  PRO   B CG  1 ? 
ATOM   3110 C CD  . PRO   B 1 96  ? 14.433  -16.733 52.259 1.000 21.153 0 96  PRO   B CD  1 ? 
ATOM   3111 N N   . LYS   B 1 97  ? 11.797  -16.450 49.691 1.000 22.791 0 97  LYS   B N   1 ? 
ATOM   3112 C CA  . LYS   B 1 97  ? 11.028  -16.173 48.484 1.000 23.969 0 97  LYS   B CA  1 ? 
ATOM   3113 C C   . LYS   B 1 97  ? 10.700  -17.449 47.712 1.000 22.363 0 97  LYS   B C   1 ? 
ATOM   3114 O O   . LYS   B 1 97  ? 10.369  -17.359 46.540 1.000 21.574 0 97  LYS   B O   1 ? 
ATOM   3115 C CB  . LYS   B 1 97  ? 11.791  -15.214 47.567 1.000 25.110 0 97  LYS   B CB  1 ? 
ATOM   3116 C CG  . LYS   B 1 97  ? 12.156  -13.877 48.185 1.000 26.975 0 97  LYS   B CG  1 ? 
ATOM   3117 C CD  . LYS   B 1 97  ? 13.176  -13.161 47.368 1.000 29.993 0 97  LYS   B CD  1 ? 
ATOM   3118 C CE  . LYS   B 1 97  ? 13.649  -11.906 48.045 1.000 34.666 0 97  LYS   B CE  1 ? 
ATOM   3119 N NZ  . LYS   B 1 97  ? 14.910  -11.440 47.433 1.000 41.133 0 97  LYS   B NZ  1 ? 
ATOM   3120 N N   . THR   B 1 98  ? 10.763  -18.625 48.355 1.000 21.647 0 98  THR   B N   1 ? 
ATOM   3121 C CA  . THR   B 1 98  ? 10.391  -19.850 47.677 1.000 21.065 0 98  THR   B CA  1 ? 
ATOM   3122 C C   . THR   B 1 98  ? 8.951   -19.701 47.201 1.000 23.175 0 98  THR   B C   1 ? 
ATOM   3123 O O   . THR   B 1 98  ? 8.077   -19.494 48.025 1.000 20.839 0 98  THR   B O   1 ? 
ATOM   3124 C CB  . THR   B 1 98  ? 10.480  -21.080 48.585 1.000 19.968 0 98  THR   B CB  1 ? 
ATOM   3125 O OG1 . THR   B 1 98  ? 11.788  -21.142 49.140 1.000 18.792 0 98  THR   B OG1 1 ? 
ATOM   3126 C CG2 . THR   B 1 98  ? 10.152  -22.354 47.842 1.000 19.270 0 98  THR   B CG2 1 ? 
ATOM   3127 N N   . PRO   B 1 99  ? 8.661   -19.797 45.882 1.000 24.988 0 99  PRO   B N   1 ? 
ATOM   3128 C CA  . PRO   B 1 99  ? 7.282   -19.808 45.392 1.000 25.200 0 99  PRO   B CA  1 ? 
ATOM   3129 C C   . PRO   B 1 99  ? 6.700   -21.217 45.508 1.000 23.449 0 99  PRO   B C   1 ? 
ATOM   3130 O O   . PRO   B 1 99  ? 7.417   -22.153 45.816 1.000 20.686 0 99  PRO   B O   1 ? 
ATOM   3131 C CB  . PRO   B 1 99  ? 7.482   -19.409 43.917 1.000 26.714 0 99  PRO   B CB  1 ? 
ATOM   3132 C CG  . PRO   B 1 99  ? 8.787   -20.106 43.533 1.000 25.998 0 99  PRO   B CG  1 ? 
ATOM   3133 C CD  . PRO   B 1 99  ? 9.633   -19.997 44.789 1.000 25.705 0 99  PRO   B CD  1 ? 
ATOM   3134 N N   . LYS   B 1 100 ? 5.397   -21.366 45.269 1.000 23.998 0 100 LYS   B N   1 ? 
ATOM   3135 C CA  . LYS   B 1 100 ? 4.828   -22.679 45.035 1.000 25.458 0 100 LYS   B CA  1 ? 
ATOM   3136 C C   . LYS   B 1 100 ? 5.495   -23.249 43.801 1.000 21.301 0 100 LYS   B C   1 ? 
ATOM   3137 O O   . LYS   B 1 100 ? 5.622   -22.558 42.790 1.000 19.769 0 100 LYS   B O   1 ? 
ATOM   3138 C CB  . LYS   B 1 100 ? 3.328   -22.662 44.722 1.000 29.752 0 100 LYS   B CB  1 ? 
ATOM   3139 C CG  . LYS   B 1 100 ? 2.424   -22.033 45.772 1.000 40.533 0 100 LYS   B CG  1 ? 
ATOM   3140 C CD  . LYS   B 1 100 ? 0.935   -22.270 45.489 1.000 48.656 0 100 LYS   B CD  1 ? 
ATOM   3141 C CE  . LYS   B 1 100 ? 0.011   -21.626 46.506 1.000 55.658 0 100 LYS   B CE  1 ? 
ATOM   3142 N NZ  . LYS   B 1 100 ? -1.388  -22.104 46.365 1.000 58.128 0 100 LYS   B NZ  1 ? 
ATOM   3143 N N   . TYR   B 1 101 ? 5.880   -24.519 43.872 1.000 19.472 0 101 TYR   B N   1 ? 
ATOM   3144 C CA  . TYR   B 1 101 ? 6.633   -25.091 42.778 1.000 18.574 0 101 TYR   B CA  1 ? 
ATOM   3145 C C   . TYR   B 1 101 ? 6.391   -26.585 42.696 1.000 20.258 0 101 TYR   B C   1 ? 
ATOM   3146 O O   . TYR   B 1 101 ? 5.978   -27.208 43.674 1.000 18.963 0 101 TYR   B O   1 ? 
ATOM   3147 C CB  . TYR   B 1 101 ? 8.116   -24.758 42.954 1.000 17.780 0 101 TYR   B CB  1 ? 
ATOM   3148 C CG  . TYR   B 1 101 ? 8.847   -25.552 44.023 1.000 19.021 0 101 TYR   B CG  1 ? 
ATOM   3149 C CD1 . TYR   B 1 101 ? 9.451   -26.777 43.754 1.000 21.087 0 101 TYR   B CD1 1 ? 
ATOM   3150 C CD2 . TYR   B 1 101 ? 8.904   -25.078 45.322 1.000 20.068 0 101 TYR   B CD2 1 ? 
ATOM   3151 C CE1 . TYR   B 1 101 ? 10.118  -27.485 44.752 1.000 21.470 0 101 TYR   B CE1 1 ? 
ATOM   3152 C CE2 . TYR   B 1 101 ? 9.560   -25.769 46.319 1.000 21.607 0 101 TYR   B CE2 1 ? 
ATOM   3153 C CZ  . TYR   B 1 101 ? 10.160  -26.983 46.039 1.000 22.296 0 101 TYR   B CZ  1 ? 
ATOM   3154 O OH  . TYR   B 1 101 ? 10.785  -27.599 47.095 1.000 24.463 0 101 TYR   B OH  1 ? 
ATOM   3155 N N   . LYS   B 1 102 ? 6.673   -27.113 41.500 1.000 20.812 0 102 LYS   B N   1 ? 
ATOM   3156 C CA  . LYS   B 1 102 ? 6.797   -28.535 41.238 1.000 23.657 0 102 LYS   B CA  1 ? 
ATOM   3157 C C   . LYS   B 1 102 ? 7.959   -28.760 40.276 1.000 19.697 0 102 LYS   B C   1 ? 
ATOM   3158 O O   . LYS   B 1 102 ? 8.367   -27.841 39.567 1.000 16.904 0 102 LYS   B O   1 ? 
ATOM   3159 C CB  . LYS   B 1 102 ? 5.534   -29.064 40.554 1.000 30.337 0 102 LYS   B CB  1 ? 
ATOM   3160 C CG  . LYS   B 1 102 ? 4.460   -29.624 41.468 1.000 40.308 0 102 LYS   B CG  1 ? 
ATOM   3161 C CD  . LYS   B 1 102 ? 3.681   -30.770 40.846 1.000 47.720 0 102 LYS   B CD  1 ? 
ATOM   3162 C CE  . LYS   B 1 102 ? 3.253   -30.512 39.412 1.000 55.101 0 102 LYS   B CE  1 ? 
ATOM   3163 N NZ  . LYS   B 1 102 ? 2.574   -29.200 39.260 1.000 57.101 0 102 LYS   B NZ  1 ? 
ATOM   3164 N N   . PHE   B 1 103 ? 8.419   -30.006 40.206 1.000 19.164 0 103 PHE   B N   1 ? 
ATOM   3165 C CA  . PHE   B 1 103 ? 9.391   -30.443 39.215 1.000 20.241 0 103 PHE   B CA  1 ? 
ATOM   3166 C C   . PHE   B 1 103 ? 8.699   -31.337 38.198 1.000 20.679 0 103 PHE   B C   1 ? 
ATOM   3167 O O   . PHE   B 1 103 ? 8.104   -32.334 38.564 1.000 24.457 0 103 PHE   B O   1 ? 
ATOM   3168 C CB  . PHE   B 1 103 ? 10.523  -31.218 39.874 1.000 19.200 0 103 PHE   B CB  1 ? 
ATOM   3169 C CG  . PHE   B 1 103 ? 11.417  -30.432 40.799 1.000 19.321 0 103 PHE   B CG  1 ? 
ATOM   3170 C CD1 . PHE   B 1 103 ? 11.438  -29.046 40.791 1.000 19.689 0 103 PHE   B CD1 1 ? 
ATOM   3171 C CD2 . PHE   B 1 103 ? 12.262  -31.105 41.670 1.000 18.848 0 103 PHE   B CD2 1 ? 
ATOM   3172 C CE1 . PHE   B 1 103 ? 12.279  -28.351 41.642 1.000 20.353 0 103 PHE   B CE1 1 ? 
ATOM   3173 C CE2 . PHE   B 1 103 ? 13.093  -30.412 42.528 1.000 19.837 0 103 PHE   B CE2 1 ? 
ATOM   3174 C CZ  . PHE   B 1 103 ? 13.105  -29.038 42.511 1.000 20.644 0 103 PHE   B CZ  1 ? 
ATOM   3175 N N   . VAL   B 1 104 ? 8.760   -30.987 36.920 1.000 18.377 0 104 VAL   B N   1 ? 
ATOM   3176 C CA  . VAL   B 1 104 ? 8.070   -31.785 35.925 1.000 19.287 0 104 VAL   B CA  1 ? 
ATOM   3177 C C   . VAL   B 1 104 ? 9.069   -32.146 34.840 1.000 18.200 0 104 VAL   B C   1 ? 
ATOM   3178 O O   . VAL   B 1 104 ? 10.040  -31.427 34.628 1.000 16.190 0 104 VAL   B O   1 ? 
ATOM   3179 C CB  . VAL   B 1 104 ? 6.859   -31.028 35.348 1.000 21.930 0 104 VAL   B CB  1 ? 
ATOM   3180 C CG1 . VAL   B 1 104 ? 5.857   -30.646 36.432 1.000 22.177 0 104 VAL   B CG1 1 ? 
ATOM   3181 C CG2 . VAL   B 1 104 ? 7.292   -29.795 34.571 1.000 23.577 0 104 VAL   B CG2 1 ? 
ATOM   3182 N N   . ARG   B 1 105 ? 8.819   -33.271 34.175 1.000 18.736 0 105 ARG   B N   1 ? 
ATOM   3183 C CA  . ARG   B 1 105 ? 9.548   -33.635 32.981 1.000 19.690 0 105 ARG   B CA  1 ? 
ATOM   3184 C C   . ARG   B 1 105 ? 8.684   -33.334 31.760 1.000 22.482 0 105 ARG   B C   1 ? 
ATOM   3185 O O   . ARG   B 1 105 ? 7.587   -33.864 31.649 1.000 22.251 0 105 ARG   B O   1 ? 
ATOM   3186 C CB  . ARG   B 1 105 ? 9.952   -35.102 33.018 1.000 20.785 0 105 ARG   B CB  1 ? 
ATOM   3187 C CG  . ARG   B 1 105 ? 11.046  -35.411 31.999 1.000 23.652 0 105 ARG   B CG  1 ? 
ATOM   3188 C CD  . ARG   B 1 105 ? 11.568  -36.822 32.115 1.000 24.417 0 105 ARG   B CD  1 ? 
ATOM   3189 N NE  . ARG   B 1 105 ? 12.477  -37.146 31.025 1.000 25.848 0 105 ARG   B NE  1 ? 
ATOM   3190 C CZ  . ARG   B 1 105 ? 13.784  -36.912 31.023 1.000 23.917 0 105 ARG   B CZ  1 ? 
ATOM   3191 N NH1 . ARG   B 1 105 ? 14.335  -36.244 32.025 1.000 25.035 0 105 ARG   B NH1 1 ? 
ATOM   3192 N NH2 . ARG   B 1 105 ? 14.537  -37.382 30.038 1.000 22.071 0 105 ARG   B NH2 1 ? 
ATOM   3193 N N   . ILE   B 1 106 ? 9.170   -32.485 30.839 1.000 22.055 0 106 ILE   B N   1 ? 
ATOM   3194 C CA  . ILE   B 1 106 ? 8.328   -32.109 29.717 1.000 22.861 0 106 ILE   B CA  1 ? 
ATOM   3195 C C   . ILE   B 1 106 ? 8.585   -33.055 28.552 1.000 22.547 0 106 ILE   B C   1 ? 
ATOM   3196 O O   . ILE   B 1 106 ? 9.549   -33.800 28.550 1.000 19.767 0 106 ILE   B O   1 ? 
ATOM   3197 C CB  . ILE   B 1 106 ? 8.499   -30.648 29.272 1.000 25.190 0 106 ILE   B CB  1 ? 
ATOM   3198 C CG1 . ILE   B 1 106 ? 9.955   -30.307 28.984 1.000 26.302 0 106 ILE   B CG1 1 ? 
ATOM   3199 C CG2 . ILE   B 1 106 ? 7.857   -29.676 30.260 1.000 28.701 0 106 ILE   B CG2 1 ? 
ATOM   3200 C CD1 . ILE   B 1 106 ? 10.081  -29.112 28.106 1.000 28.026 0 106 ILE   B CD1 1 ? 
ATOM   3201 N N   . GLN   B 1 107 ? 7.673   -32.990 27.589 1.000 23.053 0 107 GLN   B N   1 ? 
ATOM   3202 C CA  . GLN   B 1 107 ? 7.673   -33.813 26.398 1.000 24.903 0 107 GLN   B CA  1 ? 
ATOM   3203 C C   . GLN   B 1 107 ? 8.226   -32.985 25.249 1.000 23.051 0 107 GLN   B C   1 ? 
ATOM   3204 O O   . GLN   B 1 107 ? 8.036   -31.767 25.220 1.000 17.973 0 107 GLN   B O   1 ? 
ATOM   3205 C CB  . GLN   B 1 107 ? 6.237   -34.220 26.050 1.000 29.647 0 107 GLN   B CB  1 ? 
ATOM   3206 C CG  . GLN   B 1 107 ? 5.508   -34.932 27.184 1.000 36.245 0 107 GLN   B CG  1 ? 
ATOM   3207 C CD  . GLN   B 1 107 ? 5.905   -36.389 27.241 1.000 46.096 0 107 GLN   B CD  1 ? 
ATOM   3208 O OE1 . GLN   B 1 107 ? 5.333   -37.220 26.538 1.000 52.605 0 107 GLN   B OE1 1 ? 
ATOM   3209 N NE2 . GLN   B 1 107 ? 6.887   -36.711 28.073 1.000 46.917 0 107 GLN   B NE2 1 ? 
ATOM   3210 N N   . PRO   B 1 108 ? 8.857   -33.639 24.251 1.000 22.139 0 108 PRO   B N   1 ? 
ATOM   3211 C CA  . PRO   B 1 108 ? 9.225   -32.984 23.001 1.000 22.682 0 108 PRO   B CA  1 ? 
ATOM   3212 C C   . PRO   B 1 108 ? 8.011   -32.310 22.370 1.000 20.895 0 108 PRO   B C   1 ? 
ATOM   3213 O O   . PRO   B 1 108 ? 6.901   -32.847 22.378 1.000 20.119 0 108 PRO   B O   1 ? 
ATOM   3214 C CB  . PRO   B 1 108 ? 9.811   -34.099 22.102 1.000 23.517 0 108 PRO   B CB  1 ? 
ATOM   3215 C CG  . PRO   B 1 108 ? 9.457   -35.388 22.807 1.000 25.768 0 108 PRO   B CG  1 ? 
ATOM   3216 C CD  . PRO   B 1 108 ? 9.225   -35.056 24.273 1.000 23.654 0 108 PRO   B CD  1 ? 
ATOM   3217 N N   . GLY   B 1 109 ? 8.222   -31.083 21.886 1.000 19.610 0 109 GLY   B N   1 ? 
ATOM   3218 C CA  . GLY   B 1 109 ? 7.137   -30.278 21.362 1.000 19.373 0 109 GLY   B CA  1 ? 
ATOM   3219 C C   . GLY   B 1 109 ? 6.653   -29.218 22.344 1.000 19.309 0 109 GLY   B C   1 ? 
ATOM   3220 O O   . GLY   B 1 109 ? 6.162   -28.179 21.911 1.000 19.882 0 109 GLY   B O   1 ? 
ATOM   3221 N N   . GLN   B 1 110 ? 6.819   -29.460 23.655 1.000 19.379 0 110 GLN   B N   1 ? 
ATOM   3222 C CA  . GLN   B 1 110 ? 6.329   -28.528 24.659 1.000 19.013 0 110 GLN   B CA  1 ? 
ATOM   3223 C C   . GLN   B 1 110 ? 7.326   -27.374 24.818 1.000 18.317 0 110 GLN   B C   1 ? 
ATOM   3224 O O   . GLN   B 1 110 ? 8.524   -27.520 24.549 1.000 17.165 0 110 GLN   B O   1 ? 
ATOM   3225 C CB  . GLN   B 1 110 ? 6.076   -29.242 25.991 1.000 22.679 0 110 GLN   B CB  1 ? 
ATOM   3226 C CG  . GLN   B 1 110 ? 5.024   -30.348 25.945 1.000 26.051 0 110 GLN   B CG  1 ? 
ATOM   3227 C CD  . GLN   B 1 110 ? 4.619   -30.869 27.319 1.000 31.776 0 110 GLN   B CD  1 ? 
ATOM   3228 O OE1 . GLN   B 1 110 ? 5.431   -31.288 28.151 1.000 28.509 0 110 GLN   B OE1 1 ? 
ATOM   3229 N NE2 . GLN   B 1 110 ? 3.322   -30.853 27.584 1.000 35.494 0 110 GLN   B NE2 1 ? 
ATOM   3230 N N   . THR   B 1 111 ? 6.816   -26.213 25.264 1.000 16.152 0 111 THR   B N   1 ? 
ATOM   3231 C CA  . THR   B 1 111 ? 7.627   -25.019 25.414 1.000 16.006 0 111 THR   B CA  1 ? 
ATOM   3232 C C   . THR   B 1 111 ? 7.829   -24.650 26.883 1.000 14.930 0 111 THR   B C   1 ? 
ATOM   3233 O O   . THR   B 1 111 ? 7.113   -25.092 27.777 1.000 15.655 0 111 THR   B O   1 ? 
ATOM   3234 C CB  . THR   B 1 111 ? 6.999   -23.822 24.690 1.000 16.194 0 111 THR   B CB  1 ? 
ATOM   3235 O OG1 . THR   B 1 111 ? 5.676   -23.634 25.202 1.000 15.402 0 111 THR   B OG1 1 ? 
ATOM   3236 C CG2 . THR   B 1 111 ? 6.965   -24.028 23.197 1.000 15.723 0 111 THR   B CG2 1 ? 
ATOM   3237 N N   . PHE   B 1 112 ? 8.810   -23.789 27.107 1.000 14.247 0 112 PHE   B N   1 ? 
ATOM   3238 C CA  . PHE   B 1 112 ? 9.070   -23.246 28.426 1.000 14.034 0 112 PHE   B CA  1 ? 
ATOM   3239 C C   . PHE   B 1 112 ? 9.922   -22.000 28.274 1.000 13.502 0 112 PHE   B C   1 ? 
ATOM   3240 O O   . PHE   B 1 112 ? 10.440  -21.747 27.193 1.000 14.383 0 112 PHE   B O   1 ? 
ATOM   3241 C CB  . PHE   B 1 112 ? 9.715   -24.289 29.337 1.000 14.827 0 112 PHE   B CB  1 ? 
ATOM   3242 C CG  . PHE   B 1 112 ? 11.011  -24.843 28.819 1.000 16.584 0 112 PHE   B CG  1 ? 
ATOM   3243 C CD1 . PHE   B 1 112 ? 11.028  -25.916 27.949 1.000 19.291 0 112 PHE   B CD1 1 ? 
ATOM   3244 C CD2 . PHE   B 1 112 ? 12.210  -24.269 29.184 1.000 16.400 0 112 PHE   B CD2 1 ? 
ATOM   3245 C CE1 . PHE   B 1 112 ? 12.234  -26.436 27.485 1.000 20.963 0 112 PHE   B CE1 1 ? 
ATOM   3246 C CE2 . PHE   B 1 112 ? 13.407  -24.773 28.707 1.000 18.382 0 112 PHE   B CE2 1 ? 
ATOM   3247 C CZ  . PHE   B 1 112 ? 13.424  -25.859 27.860 1.000 19.728 0 112 PHE   B CZ  1 ? 
ATOM   3248 N N   . SER   B 1 113 ? 10.003  -21.223 29.358 1.000 13.868 0 113 SER   B N   1 ? 
ATOM   3249 C CA  . SER   B 1 113 ? 10.805  -20.022 29.439 1.000 13.740 0 113 SER   B CA  1 ? 
ATOM   3250 C C   . SER   B 1 113 ? 12.121  -20.348 30.122 1.000 14.145 0 113 SER   B C   1 ? 
ATOM   3251 O O   . SER   B 1 113 ? 12.158  -21.138 31.058 1.000 14.941 0 113 SER   B O   1 ? 
ATOM   3252 C CB  . SER   B 1 113 ? 10.093  -18.950 30.217 1.000 15.759 0 113 SER   B CB  1 ? 
ATOM   3253 O OG  . SER   B 1 113 ? 8.816   -18.668 29.689 1.000 16.486 0 113 SER   B OG  1 ? 
ATOM   3254 N N   . VAL   B 1 114 ? 13.192  -19.760 29.597 1.000 14.650 0 114 VAL   B N   1 ? 
ATOM   3255 C CA  . VAL   B 1 114 ? 14.521  -19.875 30.144 1.000 14.991 0 114 VAL   B CA  1 ? 
ATOM   3256 C C   . VAL   B 1 114 ? 14.894  -18.523 30.734 1.000 15.656 0 114 VAL   B C   1 ? 
ATOM   3257 O O   . VAL   B 1 114 ? 14.817  -17.501 30.046 1.000 13.352 0 114 VAL   B O   1 ? 
ATOM   3258 C CB  . VAL   B 1 114 ? 15.517  -20.295 29.052 1.000 15.452 0 114 VAL   B CB  1 ? 
ATOM   3259 C CG1 . VAL   B 1 114 ? 16.943  -20.160 29.527 1.000 16.290 0 114 VAL   B CG1 1 ? 
ATOM   3260 C CG2 . VAL   B 1 114 ? 15.212  -21.716 28.569 1.000 16.526 0 114 VAL   B CG2 1 ? 
ATOM   3261 N N   . LEU   B 1 115 ? 15.309  -18.577 32.007 1.000 15.647 0 115 LEU   B N   1 ? 
ATOM   3262 C CA  . LEU   B 1 115 ? 15.984  -17.477 32.680 1.000 16.211 0 115 LEU   B CA  1 ? 
ATOM   3263 C C   . LEU   B 1 115 ? 17.485  -17.729 32.676 1.000 15.508 0 115 LEU   B C   1 ? 
ATOM   3264 O O   . LEU   B 1 115 ? 18.009  -18.511 33.475 1.000 14.288 0 115 LEU   B O   1 ? 
ATOM   3265 C CB  . LEU   B 1 115 ? 15.438  -17.333 34.106 1.000 15.877 0 115 LEU   B CB  1 ? 
ATOM   3266 C CG  . LEU   B 1 115 ? 16.051  -16.172 34.871 1.000 16.838 0 115 LEU   B CG  1 ? 
ATOM   3267 C CD1 . LEU   B 1 115 ? 15.694  -14.851 34.198 1.000 17.117 0 115 LEU   B CD1 1 ? 
ATOM   3268 C CD2 . LEU   B 1 115 ? 15.622  -16.198 36.326 1.000 17.165 0 115 LEU   B CD2 1 ? 
ATOM   3269 N N   . ALA   B 1 116 ? 18.146  -17.128 31.691 1.000 15.003 0 116 ALA   B N   1 ? 
ATOM   3270 C CA  . ALA   B 1 116 ? 19.590  -17.217 31.568 1.000 15.360 0 116 ALA   B CA  1 ? 
ATOM   3271 C C   . ALA   B 1 116 ? 20.248  -16.338 32.630 1.000 15.751 0 116 ALA   B C   1 ? 
ATOM   3272 O O   . ALA   B 1 116 ? 19.930  -15.151 32.732 1.000 17.075 0 116 ALA   B O   1 ? 
ATOM   3273 C CB  . ALA   B 1 116 ? 19.998  -16.782 30.183 1.000 16.103 0 116 ALA   B CB  1 ? 
ATOM   3274 N N   . CYS   B 1 117 ? 21.167  -16.939 33.398 1.000 14.850 0 117 CYS   B N   1 ? 
ATOM   3275 C CA  . CYS   B 1 117 ? 21.829  -16.321 34.535 1.000 14.975 0 117 CYS   B CA  1 ? 
ATOM   3276 C C   . CYS   B 1 117 ? 23.339  -16.556 34.452 1.000 14.450 0 117 CYS   B C   1 ? 
ATOM   3277 O O   . CYS   B 1 117 ? 23.788  -17.526 33.854 1.000 12.618 0 117 CYS   B O   1 ? 
ATOM   3278 C CB  . CYS   B 1 117 ? 21.329  -16.922 35.842 1.000 17.014 0 117 CYS   B CB  1 ? 
ATOM   3279 S SG  . CYS   B 1 117 ? 19.557  -16.679 36.157 1.000 18.893 0 117 CYS   B SG  1 ? 
ATOM   3280 N N   . TYR   B 1 118 ? 24.104  -15.638 35.045 1.000 15.679 0 118 TYR   B N   1 ? 
ATOM   3281 C CA  . TYR   B 1 118 ? 25.556  -15.717 35.142 1.000 17.043 0 118 TYR   B CA  1 ? 
ATOM   3282 C C   . TYR   B 1 118 ? 25.903  -15.266 36.553 1.000 16.751 0 118 TYR   B C   1 ? 
ATOM   3283 O O   . TYR   B 1 118 ? 25.330  -14.296 37.022 1.000 16.277 0 118 TYR   B O   1 ? 
ATOM   3284 C CB  . TYR   B 1 118 ? 26.207  -14.842 34.053 1.000 18.411 0 118 TYR   B CB  1 ? 
ATOM   3285 C CG  . TYR   B 1 118 ? 25.875  -15.352 32.661 1.000 19.201 0 118 TYR   B CG  1 ? 
ATOM   3286 C CD1 . TYR   B 1 118 ? 26.540  -16.464 32.155 1.000 18.464 0 118 TYR   B CD1 1 ? 
ATOM   3287 C CD2 . TYR   B 1 118 ? 24.824  -14.812 31.920 1.000 19.764 0 118 TYR   B CD2 1 ? 
ATOM   3288 C CE1 . TYR   B 1 118 ? 26.200  -17.003 30.929 1.000 19.196 0 118 TYR   B CE1 1 ? 
ATOM   3289 C CE2 . TYR   B 1 118 ? 24.498  -15.322 30.669 1.000 22.076 0 118 TYR   B CE2 1 ? 
ATOM   3290 C CZ  . TYR   B 1 118 ? 25.189  -16.423 30.176 1.000 20.435 0 118 TYR   B CZ  1 ? 
ATOM   3291 O OH  . TYR   B 1 118 ? 24.882  -16.966 28.963 1.000 18.517 0 118 TYR   B OH  1 ? 
ATOM   3292 N N   . ASN   B 1 119 ? 26.771  -16.010 37.249 1.000 18.917 0 119 ASN   B N   1 ? 
ATOM   3293 C CA  . ASN   B 1 119 ? 27.180  -15.650 38.603 1.000 19.756 0 119 ASN   B CA  1 ? 
ATOM   3294 C C   . ASN   B 1 119 ? 25.975  -15.434 39.513 1.000 19.255 0 119 ASN   B C   1 ? 
ATOM   3295 O O   . ASN   B 1 119 ? 25.982  -14.541 40.379 1.000 19.944 0 119 ASN   B O   1 ? 
ATOM   3296 C CB  . ASN   B 1 119 ? 28.064  -14.399 38.593 1.000 21.781 0 119 ASN   B CB  1 ? 
ATOM   3297 C CG  . ASN   B 1 119 ? 29.234  -14.590 37.656 1.000 26.299 0 119 ASN   B CG  1 ? 
ATOM   3298 O OD1 . ASN   B 1 119 ? 29.385  -13.861 36.686 1.000 30.245 0 119 ASN   B OD1 1 ? 
ATOM   3299 N ND2 . ASN   B 1 119 ? 30.028  -15.619 37.882 1.000 29.661 0 119 ASN   B ND2 1 ? 
ATOM   3300 N N   . GLY   B 1 120 ? 24.934  -16.240 39.300 1.000 18.023 0 120 GLY   B N   1 ? 
ATOM   3301 C CA  . GLY   B 1 120 ? 23.748  -16.195 40.136 1.000 17.859 0 120 GLY   B CA  1 ? 
ATOM   3302 C C   . GLY   B 1 120 ? 22.847  -14.988 39.884 1.000 19.262 0 120 GLY   B C   1 ? 
ATOM   3303 O O   . GLY   B 1 120 ? 21.885  -14.816 40.611 1.000 19.066 0 120 GLY   B O   1 ? 
ATOM   3304 N N   . SER   B 1 121 ? 23.094  -14.197 38.828 1.000 21.655 0 121 SER   B N   1 ? 
ATOM   3305 C CA  . SER   B 1 121 ? 22.286  -13.006 38.571 1.000 23.374 0 121 SER   B CA  1 ? 
ATOM   3306 C C   . SER   B 1 121 ? 21.530  -13.136 37.254 1.000 19.884 0 121 SER   B C   1 ? 
ATOM   3307 O O   . SER   B 1 121 ? 22.097  -13.453 36.228 1.000 16.666 0 121 SER   B O   1 ? 
ATOM   3308 C CB  . SER   B 1 121 ? 23.122  -11.746 38.579 1.000 25.084 0 121 SER   B CB  1 ? 
ATOM   3309 O OG  . SER   B 1 121 ? 23.748  -11.577 39.849 1.000 29.448 0 121 SER   B OG  1 ? 
ATOM   3310 N N   . PRO   B 1 122 ? 20.212  -12.914 37.252 1.000 24.100 0 122 PRO   B N   1 ? 
ATOM   3311 C CA  . PRO   B 1 122 ? 19.430  -12.923 36.018 1.000 26.273 0 122 PRO   B CA  1 ? 
ATOM   3312 C C   . PRO   B 1 122 ? 19.992  -12.000 34.948 1.000 25.285 0 122 PRO   B C   1 ? 
ATOM   3313 O O   . PRO   B 1 122 ? 20.341  -10.857 35.214 1.000 27.321 0 122 PRO   B O   1 ? 
ATOM   3314 C CB  . PRO   B 1 122 ? 18.056  -12.431 36.477 1.000 30.013 0 122 PRO   B CB  1 ? 
ATOM   3315 C CG  . PRO   B 1 122 ? 17.980  -12.921 37.922 1.000 29.764 0 122 PRO   B CG  1 ? 
ATOM   3316 C CD  . PRO   B 1 122 ? 19.381  -12.717 38.449 1.000 27.710 0 122 PRO   B CD  1 ? 
ATOM   3317 N N   . SER   B 1 123 ? 20.037  -12.525 33.728 1.000 23.188 0 123 SER   B N   1 ? 
ATOM   3318 C CA  . SER   B 1 123 ? 20.598  -11.822 32.600 1.000 22.066 0 123 SER   B CA  1 ? 
ATOM   3319 C C   . SER   B 1 123 ? 19.511  -11.549 31.562 1.000 20.134 0 123 SER   B C   1 ? 
ATOM   3320 O O   . SER   B 1 123 ? 19.456  -10.467 30.990 1.000 19.956 0 123 SER   B O   1 ? 
ATOM   3321 C CB  . SER   B 1 123 ? 21.717  -12.641 32.047 1.000 23.153 0 123 SER   B CB  1 ? 
ATOM   3322 O OG  . SER   B 1 123 ? 22.271  -12.059 30.889 1.000 26.014 0 123 SER   B OG  1 ? 
ATOM   3323 N N   . GLY   B 1 124 ? 18.669  -12.540 31.286 1.000 17.528 0 124 GLY   B N   1 ? 
ATOM   3324 C CA  . GLY   B 1 124 ? 17.632  -12.361 30.288 1.000 18.113 0 124 GLY   B CA  1 ? 
ATOM   3325 C C   . GLY   B 1 124 ? 16.673  -13.538 30.273 1.000 17.842 0 124 GLY   B C   1 ? 
ATOM   3326 O O   . GLY   B 1 124 ? 16.964  -14.587 30.856 1.000 17.568 0 124 GLY   B O   1 ? 
ATOM   3327 N N   . VAL   B 1 125 ? 15.550  -13.363 29.579 1.000 18.217 0 125 VAL   B N   1 ? 
ATOM   3328 C CA  . VAL   B 1 125 ? 14.571  -14.433 29.503 1.000 19.097 0 125 VAL   B CA  1 ? 
ATOM   3329 C C   . VAL   B 1 125 ? 14.104  -14.605 28.067 1.000 17.306 0 125 VAL   B C   1 ? 
ATOM   3330 O O   . VAL   B 1 125 ? 14.039  -13.650 27.273 1.000 17.444 0 125 VAL   B O   1 ? 
ATOM   3331 C CB  . VAL   B 1 125 ? 13.440  -14.227 30.529 1.000 21.946 0 125 VAL   B CB  1 ? 
ATOM   3332 C CG1 . VAL   B 1 125 ? 12.957  -12.808 30.569 1.000 25.032 0 125 VAL   B CG1 1 ? 
ATOM   3333 C CG2 . VAL   B 1 125 ? 12.292  -15.199 30.350 1.000 22.624 0 125 VAL   B CG2 1 ? 
ATOM   3334 N N   . TYR   B 1 126 ? 13.844  -15.867 27.721 1.000 16.425 0 126 TYR   B N   1 ? 
ATOM   3335 C CA  . TYR   B 1 126 ? 13.303  -16.182 26.410 1.000 15.565 0 126 TYR   B CA  1 ? 
ATOM   3336 C C   . TYR   B 1 126 ? 12.662  -17.559 26.445 1.000 16.479 0 126 TYR   B C   1 ? 
ATOM   3337 O O   . TYR   B 1 126 ? 12.884  -18.345 27.364 1.000 14.987 0 126 TYR   B O   1 ? 
ATOM   3338 C CB  . TYR   B 1 126 ? 14.398  -16.148 25.353 1.000 16.479 0 126 TYR   B CB  1 ? 
ATOM   3339 C CG  . TYR   B 1 126 ? 15.588  -17.029 25.680 1.000 15.731 0 126 TYR   B CG  1 ? 
ATOM   3340 C CD1 . TYR   B 1 126 ? 16.654  -16.524 26.402 1.000 16.153 0 126 TYR   B CD1 1 ? 
ATOM   3341 C CD2 . TYR   B 1 126 ? 15.603  -18.377 25.347 1.000 14.949 0 126 TYR   B CD2 1 ? 
ATOM   3342 C CE1 . TYR   B 1 126 ? 17.765  -17.307 26.677 1.000 16.931 0 126 TYR   B CE1 1 ? 
ATOM   3343 C CE2 . TYR   B 1 126 ? 16.673  -19.186 25.685 1.000 14.571 0 126 TYR   B CE2 1 ? 
ATOM   3344 C CZ  . TYR   B 1 126 ? 17.758  -18.650 26.346 1.000 15.450 0 126 TYR   B CZ  1 ? 
ATOM   3345 O OH  . TYR   B 1 126 ? 18.863  -19.405 26.635 1.000 18.230 0 126 TYR   B OH  1 ? 
ATOM   3346 N N   . GLN   B 1 127 ? 11.936  -17.840 25.375 1.000 16.584 0 127 GLN   B N   1 ? 
ATOM   3347 C CA  . GLN   B 1 127 ? 11.065  -18.993 25.245 1.000 19.884 0 127 GLN   B CA  1 ? 
ATOM   3348 C C   . GLN   B 1 127 ? 11.776  -20.049 24.388 1.000 18.646 0 127 GLN   B C   1 ? 
ATOM   3349 O O   . GLN   B 1 127 ? 12.449  -19.723 23.422 1.000 18.801 0 127 GLN   B O   1 ? 
ATOM   3350 C CB  . GLN   B 1 127 ? 9.755   -18.450 24.657 1.000 22.584 0 127 GLN   B CB  1 ? 
ATOM   3351 C CG  . GLN   B 1 127 ? 8.553   -19.378 24.656 1.000 26.257 0 127 GLN   B CG  1 ? 
ATOM   3352 C CD  . GLN   B 1 127 ? 7.893   -19.617 25.986 1.000 29.608 0 127 GLN   B CD  1 ? 
ATOM   3353 O OE1 . GLN   B 1 127 ? 6.900   -20.337 26.065 1.000 34.799 0 127 GLN   B OE1 1 ? 
ATOM   3354 N NE2 . GLN   B 1 127 ? 8.460   -19.067 27.049 1.000 28.863 0 127 GLN   B NE2 1 ? 
ATOM   3355 N N   . CYS   B 1 128 ? 11.659  -21.316 24.772 1.000 19.074 0 128 CYS   B N   1 ? 
ATOM   3356 C CA  . CYS   B 1 128 ? 12.235  -22.430 24.035 1.000 20.514 0 128 CYS   B CA  1 ? 
ATOM   3357 C C   . CYS   B 1 128 ? 11.225  -23.547 23.898 1.000 18.979 0 128 CYS   B C   1 ? 
ATOM   3358 O O   . CYS   B 1 128 ? 10.329  -23.652 24.707 1.000 19.801 0 128 CYS   B O   1 ? 
ATOM   3359 C CB  . CYS   B 1 128 ? 13.372  -23.087 24.810 1.000 22.232 0 128 CYS   B CB  1 ? 
ATOM   3360 S SG  . CYS   B 1 128 ? 14.923  -22.196 24.634 1.000 31.673 0 128 CYS   B SG  1 ? 
ATOM   3361 N N   . ALA   B 1 129 ? 11.449  -24.426 22.927 1.000 20.146 0 129 ALA   B N   1 ? 
ATOM   3362 C CA  . ALA   B 1 129 ? 10.753  -25.689 22.855 1.000 18.084 0 129 ALA   B CA  1 ? 
ATOM   3363 C C   . ALA   B 1 129 ? 11.770  -26.808 23.041 1.000 17.591 0 129 ALA   B C   1 ? 
ATOM   3364 O O   . ALA   B 1 129 ? 12.930  -26.697 22.608 1.000 16.185 0 129 ALA   B O   1 ? 
ATOM   3365 C CB  . ALA   B 1 129 ? 10.028  -25.801 21.546 1.000 18.049 0 129 ALA   B CB  1 ? 
ATOM   3366 N N   . MET   B 1 130 ? 11.321  -27.863 23.739 1.000 16.501 0 130 MET   B N   1 ? 
ATOM   3367 C CA  . MET   B 1 130 ? 12.032  -29.133 23.761 1.000 16.484 0 130 MET   B CA  1 ? 
ATOM   3368 C C   . MET   B 1 130 ? 11.874  -29.725 22.369 1.000 15.733 0 130 MET   B C   1 ? 
ATOM   3369 O O   . MET   B 1 130 ? 10.766  -29.958 21.927 1.000 15.334 0 130 MET   B O   1 ? 
ATOM   3370 C CB  . MET   B 1 130 ? 11.439  -30.077 24.813 1.000 16.692 0 130 MET   B CB  1 ? 
ATOM   3371 C CG  . MET   B 1 130 ? 12.142  -31.417 24.945 1.000 16.466 0 130 MET   B CG  1 ? 
ATOM   3372 S SD  . MET   B 1 130 ? 13.915  -31.257 25.137 1.000 18.185 0 130 MET   B SD  1 ? 
ATOM   3373 C CE  . MET   B 1 130 ? 13.979  -30.542 26.782 1.000 16.236 0 130 MET   B CE  1 ? 
ATOM   3374 N N   . ARG   B 1 131 ? 12.974  -29.821 21.636 1.000 15.391 0 131 ARG   B N   1 ? 
ATOM   3375 C CA  . ARG   B 1 131 ? 12.946  -30.308 20.274 1.000 15.580 0 131 ARG   B CA  1 ? 
ATOM   3376 C C   . ARG   B 1 131 ? 12.694  -31.813 20.278 1.000 15.853 0 131 ARG   B C   1 ? 
ATOM   3377 O O   . ARG   B 1 131 ? 12.972  -32.494 21.270 1.000 17.182 0 131 ARG   B O   1 ? 
ATOM   3378 C CB  . ARG   B 1 131 ? 14.276  -29.970 19.604 1.000 15.616 0 131 ARG   B CB  1 ? 
ATOM   3379 C CG  . ARG   B 1 131 ? 14.574  -28.479 19.564 1.000 16.207 0 131 ARG   B CG  1 ? 
ATOM   3380 C CD  . ARG   B 1 131 ? 13.547  -27.658 18.796 1.000 16.350 0 131 ARG   B CD  1 ? 
ATOM   3381 N NE  . ARG   B 1 131 ? 13.181  -28.147 17.456 1.000 16.100 0 131 ARG   B NE  1 ? 
ATOM   3382 C CZ  . ARG   B 1 131 ? 12.195  -27.613 16.728 1.000 16.134 0 131 ARG   B CZ  1 ? 
ATOM   3383 N NH1 . ARG   B 1 131 ? 11.627  -26.486 17.128 1.000 14.119 0 131 ARG   B NH1 1 ? 
ATOM   3384 N NH2 . ARG   B 1 131 ? 11.790  -28.178 15.597 1.000 16.047 0 131 ARG   B NH2 1 ? 
ATOM   3385 N N   . PRO   B 1 132 ? 12.173  -32.394 19.178 1.000 15.963 0 132 PRO   B N   1 ? 
ATOM   3386 C CA  . PRO   B 1 132 ? 12.022  -33.850 19.089 1.000 17.270 0 132 PRO   B CA  1 ? 
ATOM   3387 C C   . PRO   B 1 132 ? 13.322  -34.633 19.289 1.000 17.035 0 132 PRO   B C   1 ? 
ATOM   3388 O O   . PRO   B 1 132 ? 13.275  -35.762 19.737 1.000 17.607 0 132 PRO   B O   1 ? 
ATOM   3389 C CB  . PRO   B 1 132 ? 11.433  -34.057 17.680 1.000 17.557 0 132 PRO   B CB  1 ? 
ATOM   3390 C CG  . PRO   B 1 132 ? 10.677  -32.761 17.435 1.000 17.505 0 132 PRO   B CG  1 ? 
ATOM   3391 C CD  . PRO   B 1 132 ? 11.582  -31.695 18.024 1.000 16.825 0 132 PRO   B CD  1 ? 
ATOM   3392 N N   . ASN   B 1 133 ? 14.471  -34.033 18.953 1.000 17.453 0 133 ASN   B N   1 ? 
ATOM   3393 C CA  . ASN   B 1 133 ? 15.761  -34.665 19.202 1.000 18.247 0 133 ASN   B CA  1 ? 
ATOM   3394 C C   . ASN   B 1 133 ? 16.316  -34.313 20.590 1.000 19.119 0 133 ASN   B C   1 ? 
ATOM   3395 O O   . ASN   B 1 133 ? 17.506  -34.516 20.825 1.000 17.572 0 133 ASN   B O   1 ? 
ATOM   3396 C CB  . ASN   B 1 133 ? 16.771  -34.303 18.115 1.000 17.550 0 133 ASN   B CB  1 ? 
ATOM   3397 C CG  . ASN   B 1 133 ? 17.231  -32.862 18.179 1.000 16.320 0 133 ASN   B CG  1 ? 
ATOM   3398 O OD1 . ASN   B 1 133 ? 16.804  -32.116 19.053 1.000 15.445 0 133 ASN   B OD1 1 ? 
ATOM   3399 N ND2 . ASN   B 1 133 ? 18.137  -32.483 17.292 1.000 15.890 0 133 ASN   B ND2 1 ? 
ATOM   3400 N N   . PHE   B 1 134 ? 15.479  -33.760 21.490 1.000 17.494 0 134 PHE   B N   1 ? 
ATOM   3401 C CA  . PHE   B 1 134 ? 15.822  -33.569 22.898 1.000 17.814 0 134 PHE   B CA  1 ? 
ATOM   3402 C C   . PHE   B 1 134 ? 16.960  -32.569 23.086 1.000 17.143 0 134 PHE   B C   1 ? 
ATOM   3403 O O   . PHE   B 1 134 ? 17.670  -32.629 24.088 1.000 17.330 0 134 PHE   B O   1 ? 
ATOM   3404 C CB  . PHE   B 1 134 ? 16.124  -34.895 23.618 1.000 19.429 0 134 PHE   B CB  1 ? 
ATOM   3405 C CG  . PHE   B 1 134 ? 14.966  -35.863 23.631 1.000 21.312 0 134 PHE   B CG  1 ? 
ATOM   3406 C CD1 . PHE   B 1 134 ? 13.825  -35.597 24.375 1.000 23.489 0 134 PHE   B CD1 1 ? 
ATOM   3407 C CD2 . PHE   B 1 134 ? 14.996  -37.011 22.854 1.000 25.502 0 134 PHE   B CD2 1 ? 
ATOM   3408 C CE1 . PHE   B 1 134 ? 12.758  -36.481 24.379 1.000 26.275 0 134 PHE   B CE1 1 ? 
ATOM   3409 C CE2 . PHE   B 1 134 ? 13.916  -37.886 22.833 1.000 27.530 0 134 PHE   B CE2 1 ? 
ATOM   3410 C CZ  . PHE   B 1 134 ? 12.809  -37.629 23.611 1.000 27.936 0 134 PHE   B CZ  1 ? 
ATOM   3411 N N   . THR   B 1 135 ? 17.068  -31.595 22.179 1.000 16.724 0 135 THR   B N   1 ? 
ATOM   3412 C CA  . THR   B 1 135 ? 17.870  -30.421 22.447 1.000 17.797 0 135 THR   B CA  1 ? 
ATOM   3413 C C   . THR   B 1 135 ? 16.965  -29.196 22.553 1.000 16.859 0 135 THR   B C   1 ? 
ATOM   3414 O O   . THR   B 1 135 ? 15.789  -29.256 22.229 1.000 15.391 0 135 THR   B O   1 ? 
ATOM   3415 C CB  . THR   B 1 135 ? 18.937  -30.228 21.366 1.000 18.856 0 135 THR   B CB  1 ? 
ATOM   3416 O OG1 . THR   B 1 135 ? 18.263  -29.866 20.169 1.000 17.476 0 135 THR   B OG1 1 ? 
ATOM   3417 C CG2 . THR   B 1 135 ? 19.775  -31.473 21.152 1.000 19.575 0 135 THR   B CG2 1 ? 
ATOM   3418 N N   . ILE   B 1 136 ? 17.536  -28.081 23.004 1.000 15.843 0 136 ILE   B N   1 ? 
ATOM   3419 C CA  . ILE   B 1 136 ? 16.870  -26.793 22.895 1.000 16.428 0 136 ILE   B CA  1 ? 
ATOM   3420 C C   . ILE   B 1 136 ? 17.790  -25.850 22.118 1.000 16.604 0 136 ILE   B C   1 ? 
ATOM   3421 O O   . ILE   B 1 136 ? 19.019  -25.993 22.095 1.000 15.782 0 136 ILE   B O   1 ? 
ATOM   3422 C CB  . ILE   B 1 136 ? 16.455  -26.257 24.285 1.000 17.275 0 136 ILE   B CB  1 ? 
ATOM   3423 C CG1 . ILE   B 1 136 ? 17.635  -25.816 25.150 1.000 17.516 0 136 ILE   B CG1 1 ? 
ATOM   3424 C CG2 . ILE   B 1 136 ? 15.620  -27.291 25.025 1.000 17.647 0 136 ILE   B CG2 1 ? 
ATOM   3425 C CD1 . ILE   B 1 136 ? 17.210  -25.234 26.472 1.000 19.235 0 136 ILE   B CD1 1 ? 
ATOM   3426 N N   . LYS   B 1 137 ? 17.164  -24.910 21.435 1.000 16.908 0 137 LYS   B N   1 ? 
ATOM   3427 C CA  . LYS   B 1 137 ? 17.884  -23.886 20.699 1.000 18.350 0 137 LYS   B CA  1 ? 
ATOM   3428 C C   . LYS   B 1 137 ? 17.947  -22.648 21.577 1.000 17.457 0 137 LYS   B C   1 ? 
ATOM   3429 O O   . LYS   B 1 137 ? 17.134  -21.749 21.461 1.000 18.054 0 137 LYS   B O   1 ? 
ATOM   3430 C CB  . LYS   B 1 137 ? 17.168  -23.599 19.384 1.000 20.128 0 137 LYS   B CB  1 ? 
ATOM   3431 C CG  . LYS   B 1 137 ? 17.173  -24.742 18.388 1.000 22.451 0 137 LYS   B CG  1 ? 
ATOM   3432 C CD  . LYS   B 1 137 ? 16.330  -24.437 17.179 1.000 26.590 0 137 LYS   B CD  1 ? 
ATOM   3433 C CE  . LYS   B 1 137 ? 16.409  -25.542 16.155 1.000 30.570 0 137 LYS   B CE  1 ? 
ATOM   3434 N NZ  . LYS   B 1 137 ? 15.389  -25.349 15.089 1.000 35.013 0 137 LYS   B NZ  1 ? 
ATOM   3435 N N   . GLY   B 1 138 ? 18.879  -22.664 22.526 1.000 17.985 0 138 GLY   B N   1 ? 
ATOM   3436 C CA  . GLY   B 1 138 ? 18.989  -21.621 23.517 1.000 16.757 0 138 GLY   B CA  1 ? 
ATOM   3437 C C   . GLY   B 1 138 ? 20.069  -20.607 23.158 1.000 16.709 0 138 GLY   B C   1 ? 
ATOM   3438 O O   . GLY   B 1 138 ? 20.548  -20.556 22.035 1.000 16.411 0 138 GLY   B O   1 ? 
ATOM   3439 N N   . SER   B 1 139 ? 20.400  -19.785 24.150 1.000 15.644 0 139 SER   B N   1 ? 
ATOM   3440 C CA  . SER   B 1 139 ? 21.466  -18.816 24.060 1.000 15.798 0 139 SER   B CA  1 ? 
ATOM   3441 C C   . SER   B 1 139 ? 22.202  -18.834 25.390 1.000 15.831 0 139 SER   B C   1 ? 
ATOM   3442 O O   . SER   B 1 139 ? 21.697  -18.339 26.393 1.000 16.114 0 139 SER   B O   1 ? 
ATOM   3443 C CB  . SER   B 1 139 ? 20.927  -17.458 23.711 1.000 15.490 0 139 SER   B CB  1 ? 
ATOM   3444 O OG  . SER   B 1 139 ? 21.953  -16.485 23.761 1.000 15.358 0 139 SER   B OG  1 ? 
ATOM   3445 N N   . PHE   B 1 140 ? 23.378  -19.460 25.400 1.000 16.373 0 140 PHE   B N   1 ? 
ATOM   3446 C CA  . PHE   B 1 140 ? 24.042  -19.763 26.658 1.000 16.731 0 140 PHE   B CA  1 ? 
ATOM   3447 C C   . PHE   B 1 140 ? 25.548  -19.641 26.498 1.000 17.326 0 140 PHE   B C   1 ? 
ATOM   3448 O O   . PHE   B 1 140 ? 26.135  -20.243 25.600 1.000 17.100 0 140 PHE   B O   1 ? 
ATOM   3449 C CB  . PHE   B 1 140 ? 23.747  -21.191 27.118 1.000 15.487 0 140 PHE   B CB  1 ? 
ATOM   3450 C CG  . PHE   B 1 140 ? 22.357  -21.504 27.608 1.000 13.666 0 140 PHE   B CG  1 ? 
ATOM   3451 C CD1 . PHE   B 1 140 ? 21.878  -20.998 28.805 1.000 14.539 0 140 PHE   B CD1 1 ? 
ATOM   3452 C CD2 . PHE   B 1 140 ? 21.533  -22.344 26.876 1.000 14.010 0 140 PHE   B CD2 1 ? 
ATOM   3453 C CE1 . PHE   B 1 140 ? 20.611  -21.337 29.256 1.000 14.543 0 140 PHE   B CE1 1 ? 
ATOM   3454 C CE2 . PHE   B 1 140 ? 20.273  -22.696 27.328 1.000 14.176 0 140 PHE   B CE2 1 ? 
ATOM   3455 C CZ  . PHE   B 1 140 ? 19.820  -22.211 28.529 1.000 14.491 0 140 PHE   B CZ  1 ? 
ATOM   3456 N N   . LEU   B 1 141 ? 26.144  -18.858 27.396 1.000 18.993 0 141 LEU   B N   1 ? 
ATOM   3457 C CA  . LEU   B 1 141 ? 27.583  -18.693 27.460 1.000 20.975 0 141 LEU   B CA  1 ? 
ATOM   3458 C C   . LEU   B 1 141 ? 28.150  -19.400 28.685 1.000 21.407 0 141 LEU   B C   1 ? 
ATOM   3459 O O   . LEU   B 1 141 ? 27.427  -19.995 29.482 1.000 20.126 0 141 LEU   B O   1 ? 
ATOM   3460 C CB  . LEU   B 1 141 ? 27.917  -17.207 27.531 1.000 22.516 0 141 LEU   B CB  1 ? 
ATOM   3461 C CG  . LEU   B 1 141 ? 27.453  -16.357 26.347 1.000 24.594 0 141 LEU   B CG  1 ? 
ATOM   3462 C CD1 . LEU   B 1 141 ? 27.680  -14.896 26.677 1.000 25.631 0 141 LEU   B CD1 1 ? 
ATOM   3463 C CD2 . LEU   B 1 141 ? 28.206  -16.717 25.081 1.000 24.593 0 141 LEU   B CD2 1 ? 
ATOM   3464 N N   . ASN   B 1 142 ? 29.478  -19.353 28.789 1.000 20.988 0 142 ASN   B N   1 ? 
ATOM   3465 C CA  . ASN   B 1 142 ? 30.144  -19.972 29.904 1.000 23.002 0 142 ASN   B CA  1 ? 
ATOM   3466 C C   . ASN   B 1 142 ? 29.700  -19.214 31.156 1.000 21.617 0 142 ASN   B C   1 ? 
ATOM   3467 O O   . ASN   B 1 142 ? 29.631  -17.983 31.181 1.000 19.345 0 142 ASN   B O   1 ? 
ATOM   3468 C CB  . ASN   B 1 142 ? 31.657  -20.057 29.669 1.000 26.785 0 142 ASN   B CB  1 ? 
ATOM   3469 C CG  . ASN   B 1 142 ? 32.306  -21.023 30.636 1.000 33.094 0 142 ASN   B CG  1 ? 
ATOM   3470 O OD1 . ASN   B 1 142 ? 33.368  -20.740 31.173 1.000 36.221 0 142 ASN   B OD1 1 ? 
ATOM   3471 N ND2 . ASN   B 1 142 ? 31.671  -22.162 30.877 1.000 35.351 0 142 ASN   B ND2 1 ? 
ATOM   3472 N N   . GLY   B 1 143 ? 29.345  -19.995 32.175 1.000 17.361 0 143 GLY   B N   1 ? 
ATOM   3473 C CA  . GLY   B 1 143 ? 28.769  -19.447 33.377 1.000 17.548 0 143 GLY   B CA  1 ? 
ATOM   3474 C C   . GLY   B 1 143 ? 27.263  -19.659 33.430 1.000 15.979 0 143 GLY   B C   1 ? 
ATOM   3475 O O   . GLY   B 1 143 ? 26.687  -19.453 34.470 1.000 14.356 0 143 GLY   B O   1 ? 
ATOM   3476 N N   . SER   B 1 144 ? 26.634  -20.057 32.313 1.000 15.913 0 144 SER   B N   1 ? 
ATOM   3477 C CA  . SER   B 1 144 ? 25.180  -20.189 32.255 1.000 15.190 0 144 SER   B CA  1 ? 
ATOM   3478 C C   . SER   B 1 144 ? 24.657  -21.470 32.916 1.000 14.340 0 144 SER   B C   1 ? 
ATOM   3479 O O   . SER   B 1 144 ? 23.462  -21.557 33.260 1.000 12.768 0 144 SER   B O   1 ? 
ATOM   3480 C CB  . SER   B 1 144 ? 24.687  -20.083 30.827 1.000 14.834 0 144 SER   B CB  1 ? 
ATOM   3481 O OG  . SER   B 1 144 ? 25.149  -21.155 30.023 1.000 13.323 0 144 SER   B OG  1 ? 
ATOM   3482 N N   . CYS   B 1 145 ? 25.512  -22.496 33.069 1.000 14.891 0 145 CYS   B N   1 ? 
ATOM   3483 C CA  . CYS   B 1 145 ? 25.034  -23.765 33.611 1.000 15.289 0 145 CYS   B CA  1 ? 
ATOM   3484 C C   . CYS   B 1 145 ? 24.325  -23.524 34.941 1.000 14.511 0 145 CYS   B C   1 ? 
ATOM   3485 O O   . CYS   B 1 145 ? 24.728  -22.667 35.736 1.000 12.995 0 145 CYS   B O   1 ? 
ATOM   3486 C CB  . CYS   B 1 145 ? 26.135  -24.799 33.822 1.000 16.928 0 145 CYS   B CB  1 ? 
ATOM   3487 S SG  . CYS   B 1 145 ? 26.935  -25.329 32.289 1.000 19.353 0 145 CYS   B SG  1 ? 
ATOM   3488 N N   . GLY   B 1 146 ? 23.242  -24.277 35.158 1.000 14.175 0 146 GLY   B N   1 ? 
ATOM   3489 C CA  . GLY   B 1 146 ? 22.412  -24.087 36.343 1.000 14.352 0 146 GLY   B CA  1 ? 
ATOM   3490 C C   . GLY   B 1 146 ? 21.229  -23.140 36.107 1.000 13.610 0 146 GLY   B C   1 ? 
ATOM   3491 O O   . GLY   B 1 146 ? 20.328  -23.084 36.946 1.000 11.979 0 146 GLY   B O   1 ? 
ATOM   3492 N N   . SER   B 1 147 ? 21.221  -22.412 34.971 1.000 13.295 0 147 SER   B N   1 ? 
ATOM   3493 C CA  . SER   B 1 147 ? 20.054  -21.643 34.560 1.000 13.328 0 147 SER   B CA  1 ? 
ATOM   3494 C C   . SER   B 1 147 ? 18.901  -22.617 34.332 1.000 14.509 0 147 SER   B C   1 ? 
ATOM   3495 O O   . SER   B 1 147 ? 19.133  -23.766 33.940 1.000 15.064 0 147 SER   B O   1 ? 
ATOM   3496 C CB  . SER   B 1 147 ? 20.307  -20.822 33.306 1.000 13.430 0 147 SER   B CB  1 ? 
ATOM   3497 O OG  . SER   B 1 147 ? 21.363  -19.885 33.507 1.000 12.294 0 147 SER   B OG  1 ? 
ATOM   3498 N N   . VAL   B 1 148 ? 17.674  -22.203 34.665 1.000 14.195 0 148 VAL   B N   1 ? 
ATOM   3499 C CA  . VAL   B 1 148 ? 16.549  -23.119 34.618 1.000 14.071 0 148 VAL   B CA  1 ? 
ATOM   3500 C C   . VAL   B 1 148 ? 15.545  -22.706 33.557 1.000 13.719 0 148 VAL   B C   1 ? 
ATOM   3501 O O   . VAL   B 1 148 ? 15.467  -21.551 33.177 1.000 13.377 0 148 VAL   B O   1 ? 
ATOM   3502 C CB  . VAL   B 1 148 ? 15.869  -23.255 35.981 1.000 15.155 0 148 VAL   B CB  1 ? 
ATOM   3503 C CG1 . VAL   B 1 148 ? 16.775  -23.992 36.958 1.000 15.842 0 148 VAL   B CG1 1 ? 
ATOM   3504 C CG2 . VAL   B 1 148 ? 15.421  -21.902 36.522 1.000 15.093 0 148 VAL   B CG2 1 ? 
ATOM   3505 N N   . GLY   B 1 149 ? 14.750  -23.696 33.153 1.000 14.044 0 149 GLY   B N   1 ? 
ATOM   3506 C CA  . GLY   B 1 149 ? 13.564  -23.511 32.345 1.000 13.792 0 149 GLY   B CA  1 ? 
ATOM   3507 C C   . GLY   B 1 149 ? 12.335  -23.863 33.171 1.000 14.920 0 149 GLY   B C   1 ? 
ATOM   3508 O O   . GLY   B 1 149 ? 12.412  -24.722 34.058 1.000 13.518 0 149 GLY   B O   1 ? 
ATOM   3509 N N   . PHE   B 1 150 ? 11.232  -23.143 32.913 1.000 14.698 0 150 PHE   B N   1 ? 
ATOM   3510 C CA  . PHE   B 1 150 ? 10.050  -23.269 33.745 1.000 15.730 0 150 PHE   B CA  1 ? 
ATOM   3511 C C   . PHE   B 1 150 ? 8.808   -22.817 32.981 1.000 16.882 0 150 PHE   B C   1 ? 
ATOM   3512 O O   . PHE   B 1 150 ? 8.897   -22.042 32.013 1.000 15.936 0 150 PHE   B O   1 ? 
ATOM   3513 C CB  . PHE   B 1 150 ? 10.148  -22.390 34.999 1.000 15.951 0 150 PHE   B CB  1 ? 
ATOM   3514 C CG  . PHE   B 1 150 ? 10.328  -20.930 34.690 1.000 16.818 0 150 PHE   B CG  1 ? 
ATOM   3515 C CD1 . PHE   B 1 150 ? 11.552  -20.440 34.263 1.000 16.573 0 150 PHE   B CD1 1 ? 
ATOM   3516 C CD2 . PHE   B 1 150 ? 9.254   -20.060 34.756 1.000 17.420 0 150 PHE   B CD2 1 ? 
ATOM   3517 C CE1 . PHE   B 1 150 ? 11.706  -19.099 33.962 1.000 17.478 0 150 PHE   B CE1 1 ? 
ATOM   3518 C CE2 . PHE   B 1 150 ? 9.412   -18.714 34.470 1.000 16.990 0 150 PHE   B CE2 1 ? 
ATOM   3519 C CZ  . PHE   B 1 150 ? 10.632  -18.237 34.057 1.000 17.209 0 150 PHE   B CZ  1 ? 
ATOM   3520 N N   . ASN   B 1 151 ? 7.671   -23.323 33.459 1.000 16.899 0 151 ASN   B N   1 ? 
ATOM   3521 C CA  . ASN   B 1 151 ? 6.356   -22.785 33.151 1.000 19.037 0 151 ASN   B CA  1 ? 
ATOM   3522 C C   . ASN   B 1 151 ? 5.708   -22.281 34.439 1.000 21.620 0 151 ASN   B C   1 ? 
ATOM   3523 O O   . ASN   B 1 151 ? 6.055   -22.691 35.548 1.000 21.152 0 151 ASN   B O   1 ? 
ATOM   3524 C CB  . ASN   B 1 151 ? 5.486   -23.822 32.437 1.000 18.065 0 151 ASN   B CB  1 ? 
ATOM   3525 C CG  . ASN   B 1 151 ? 5.946   -24.048 31.012 1.000 18.858 0 151 ASN   B CG  1 ? 
ATOM   3526 O OD1 . ASN   B 1 151 ? 5.657   -23.257 30.126 1.000 24.779 0 151 ASN   B OD1 1 ? 
ATOM   3527 N ND2 . ASN   B 1 151 ? 6.688   -25.100 30.764 1.000 18.451 0 151 ASN   B ND2 1 ? 
ATOM   3528 N N   . ILE   B 1 152 ? 4.789   -21.334 34.280 1.000 23.871 0 152 ILE   B N   1 ? 
ATOM   3529 C CA  . ILE   B 1 152 ? 3.998   -20.850 35.390 1.000 25.209 0 152 ILE   B CA  1 ? 
ATOM   3530 C C   . ILE   B 1 152 ? 2.549   -21.171 35.056 1.000 30.451 0 152 ILE   B C   1 ? 
ATOM   3531 O O   . ILE   B 1 152 ? 2.086   -20.884 33.952 1.000 28.628 0 152 ILE   B O   1 ? 
ATOM   3532 C CB  . ILE   B 1 152 ? 4.208   -19.346 35.644 1.000 24.691 0 152 ILE   B CB  1 ? 
ATOM   3533 C CG1 . ILE   B 1 152 ? 5.668   -19.024 35.959 1.000 26.144 0 152 ILE   B CG1 1 ? 
ATOM   3534 C CG2 . ILE   B 1 152 ? 3.279   -18.858 36.762 1.000 26.927 0 152 ILE   B CG2 1 ? 
ATOM   3535 C CD1 . ILE   B 1 152 ? 5.948   -17.560 36.175 1.000 29.019 0 152 ILE   B CD1 1 ? 
ATOM   3536 N N   . ASP   B 1 153 ? 1.865   -21.785 36.016 1.000 32.114 0 153 ASP   B N   1 ? 
ATOM   3537 C CA  . ASP   B 1 153 ? 0.435   -22.007 35.917 1.000 39.615 0 153 ASP   B CA  1 ? 
ATOM   3538 C C   . ASP   B 1 153 ? -0.216  -21.391 37.147 1.000 34.677 0 153 ASP   B C   1 ? 
ATOM   3539 O O   . ASP   B 1 153 ? -0.056  -21.919 38.242 1.000 34.242 0 153 ASP   B O   1 ? 
ATOM   3540 C CB  . ASP   B 1 153 ? 0.095   -23.493 35.811 1.000 46.539 0 153 ASP   B CB  1 ? 
ATOM   3541 C CG  . ASP   B 1 153 ? -1.406  -23.713 35.878 1.000 60.661 0 153 ASP   B CG  1 ? 
ATOM   3542 O OD1 . ASP   B 1 153 ? -2.132  -23.065 35.078 1.000 68.868 0 153 ASP   B OD1 1 ? 
ATOM   3543 O OD2 . ASP   B 1 153 ? -1.844  -24.490 36.747 1.000 69.763 0 153 ASP   B OD2 1 ? 
ATOM   3544 N N   . TYR   B 1 154 ? -0.906  -20.265 36.939 1.000 37.300 0 154 TYR   B N   1 ? 
ATOM   3545 C CA  . TYR   B 1 154 ? -1.476  -19.444 38.001 1.000 41.949 0 154 TYR   B CA  1 ? 
ATOM   3546 C C   . TYR   B 1 154 ? -0.333  -18.915 38.857 1.000 39.235 0 154 TYR   B C   1 ? 
ATOM   3547 O O   . TYR   B 1 154 ? 0.385   -18.016 38.433 1.000 44.149 0 154 TYR   B O   1 ? 
ATOM   3548 C CB  . TYR   B 1 154 ? -2.603  -20.169 38.756 1.000 45.061 0 154 TYR   B CB  1 ? 
ATOM   3549 C CG  . TYR   B 1 154 ? -3.779  -20.437 37.828 1.000 56.048 0 154 TYR   B CG  1 ? 
ATOM   3550 C CD1 . TYR   B 1 154 ? -4.560  -19.392 37.345 1.000 60.658 0 154 TYR   B CD1 1 ? 
ATOM   3551 C CD2 . TYR   B 1 154 ? -4.049  -21.721 37.352 1.000 61.973 0 154 TYR   B CD2 1 ? 
ATOM   3552 C CE1 . TYR   B 1 154 ? -5.607  -19.619 36.463 1.000 65.467 0 154 TYR   B CE1 1 ? 
ATOM   3553 C CE2 . TYR   B 1 154 ? -5.093  -21.960 36.470 1.000 65.415 0 154 TYR   B CE2 1 ? 
ATOM   3554 C CZ  . TYR   B 1 154 ? -5.874  -20.906 36.024 1.000 66.838 0 154 TYR   B CZ  1 ? 
ATOM   3555 O OH  . TYR   B 1 154 ? -6.904  -21.131 35.156 1.000 68.770 0 154 TYR   B OH  1 ? 
ATOM   3556 N N   . ASP   B 1 155 ? -0.158  -19.485 40.047 1.000 38.681 0 155 ASP   B N   1 ? 
ATOM   3557 C CA  . ASP   B 1 155 ? 0.892   -19.042 40.950 1.000 40.263 0 155 ASP   B CA  1 ? 
ATOM   3558 C C   . ASP   B 1 155 ? 1.980   -20.107 41.111 1.000 32.895 0 155 ASP   B C   1 ? 
ATOM   3559 O O   . ASP   B 1 155 ? 2.918   -19.886 41.876 1.000 35.939 0 155 ASP   B O   1 ? 
ATOM   3560 C CB  . ASP   B 1 155 ? 0.285   -18.676 42.310 1.000 44.137 0 155 ASP   B CB  1 ? 
ATOM   3561 C CG  . ASP   B 1 155 ? -0.581  -19.768 42.923 1.000 48.564 0 155 ASP   B CG  1 ? 
ATOM   3562 O OD1 . ASP   B 1 155 ? -0.894  -20.774 42.212 1.000 40.415 0 155 ASP   B OD1 1 ? 
ATOM   3563 O OD2 . ASP   B 1 155 ? -0.940  -19.613 44.115 1.000 57.064 0 155 ASP   B OD2 1 ? 
ATOM   3564 N N   . CYS   B 1 156 ? 1.836   -21.266 40.439 1.000 30.186 0 156 CYS   B N   1 ? 
ATOM   3565 C CA  . CYS   B 1 156 ? 2.737   -22.397 40.628 1.000 27.915 0 156 CYS   B CA  1 ? 
ATOM   3566 C C   . CYS   B 1 156 ? 3.823   -22.417 39.541 1.000 24.981 0 156 CYS   B C   1 ? 
ATOM   3567 O O   . CYS   B 1 156 ? 3.523   -22.453 38.358 1.000 23.891 0 156 CYS   B O   1 ? 
ATOM   3568 C CB  . CYS   B 1 156 ? 1.981   -23.719 40.603 1.000 27.977 0 156 CYS   B CB  1 ? 
ATOM   3569 S SG  . CYS   B 1 156 ? 3.041   -25.147 40.976 1.000 33.459 0 156 CYS   B SG  1 ? 
ATOM   3570 N N   . VAL   B 1 157 ? 5.090   -22.452 39.952 1.000 24.231 0 157 VAL   B N   1 ? 
ATOM   3571 C CA  . VAL   B 1 157 ? 6.214   -22.576 39.035 1.000 22.970 0 157 VAL   B CA  1 ? 
ATOM   3572 C C   . VAL   B 1 157 ? 6.524   -24.058 38.833 1.000 21.338 0 157 VAL   B C   1 ? 
ATOM   3573 O O   . VAL   B 1 157 ? 6.933   -24.726 39.774 1.000 24.388 0 157 VAL   B O   1 ? 
ATOM   3574 C CB  . VAL   B 1 157 ? 7.472   -21.854 39.563 1.000 20.995 0 157 VAL   B CB  1 ? 
ATOM   3575 C CG1 . VAL   B 1 157 ? 8.591   -21.904 38.533 1.000 20.413 0 157 VAL   B CG1 1 ? 
ATOM   3576 C CG2 . VAL   B 1 157 ? 7.191   -20.426 39.980 1.000 21.674 0 157 VAL   B CG2 1 ? 
ATOM   3577 N N   . SER   B 1 158 ? 6.410   -24.520 37.588 1.000 18.666 0 158 SER   B N   1 ? 
ATOM   3578 C CA  . SER   B 1 158 ? 6.843   -25.834 37.168 1.000 18.128 0 158 SER   B CA  1 ? 
ATOM   3579 C C   . SER   B 1 158 ? 8.230   -25.750 36.548 1.000 16.437 0 158 SER   B C   1 ? 
ATOM   3580 O O   . SER   B 1 158 ? 8.362   -25.371 35.389 1.000 15.573 0 158 SER   B O   1 ? 
ATOM   3581 C CB  . SER   B 1 158 ? 5.854   -26.434 36.202 1.000 19.384 0 158 SER   B CB  1 ? 
ATOM   3582 O OG  . SER   B 1 158 ? 4.677   -26.793 36.908 1.000 22.554 0 158 SER   B OG  1 ? 
ATOM   3583 N N   . PHE   B 1 159 ? 9.249   -26.106 37.334 1.000 15.013 0 159 PHE   B N   1 ? 
ATOM   3584 C CA  . PHE   B 1 159 ? 10.610  -26.237 36.829 1.000 16.143 0 159 PHE   B CA  1 ? 
ATOM   3585 C C   . PHE   B 1 159 ? 10.757  -27.498 35.972 1.000 17.013 0 159 PHE   B C   1 ? 
ATOM   3586 O O   . PHE   B 1 159 ? 10.437  -28.595 36.423 1.000 17.781 0 159 PHE   B O   1 ? 
ATOM   3587 C CB  . PHE   B 1 159 ? 11.577  -26.223 38.003 1.000 15.727 0 159 PHE   B CB  1 ? 
ATOM   3588 C CG  . PHE   B 1 159 ? 11.614  -24.921 38.761 1.000 15.419 0 159 PHE   B CG  1 ? 
ATOM   3589 C CD1 . PHE   B 1 159 ? 12.207  -23.800 38.205 1.000 14.726 0 159 PHE   B CD1 1 ? 
ATOM   3590 C CD2 . PHE   B 1 159 ? 11.028  -24.806 40.015 1.000 14.828 0 159 PHE   B CD2 1 ? 
ATOM   3591 C CE1 . PHE   B 1 159 ? 12.292  -22.622 38.926 1.000 15.241 0 159 PHE   B CE1 1 ? 
ATOM   3592 C CE2 . PHE   B 1 159 ? 11.117  -23.625 40.733 1.000 15.275 0 159 PHE   B CE2 1 ? 
ATOM   3593 C CZ  . PHE   B 1 159 ? 11.731  -22.529 40.179 1.000 14.816 0 159 PHE   B CZ  1 ? 
ATOM   3594 N N   . CYS   B 1 160 ? 11.190  -27.335 34.712 1.000 16.649 0 160 CYS   B N   1 ? 
ATOM   3595 C CA  . CYS   B 1 160 ? 11.312  -28.473 33.814 1.000 17.379 0 160 CYS   B CA  1 ? 
ATOM   3596 C C   . CYS   B 1 160 ? 12.744  -28.679 33.296 1.000 17.863 0 160 CYS   B C   1 ? 
ATOM   3597 O O   . CYS   B 1 160 ? 13.043  -29.738 32.744 1.000 17.025 0 160 CYS   B O   1 ? 
ATOM   3598 C CB  . CYS   B 1 160 ? 10.333  -28.348 32.649 1.000 17.638 0 160 CYS   B CB  1 ? 
ATOM   3599 S SG  . CYS   B 1 160 ? 10.588  -26.875 31.626 1.000 20.002 0 160 CYS   B SG  1 ? 
ATOM   3600 N N   . TYR   B 1 161 ? 13.643  -27.695 33.459 1.000 16.235 0 161 TYR   B N   1 ? 
ATOM   3601 C CA  . TYR   B 1 161 ? 14.924  -27.770 32.765 1.000 15.230 0 161 TYR   B CA  1 ? 
ATOM   3602 C C   . TYR   B 1 161 ? 16.002  -27.094 33.600 1.000 14.291 0 161 TYR   B C   1 ? 
ATOM   3603 O O   . TYR   B 1 161 ? 15.748  -26.054 34.203 1.000 12.893 0 161 TYR   B O   1 ? 
ATOM   3604 C CB  . TYR   B 1 161 ? 14.903  -27.051 31.408 1.000 15.883 0 161 TYR   B CB  1 ? 
ATOM   3605 C CG  . TYR   B 1 161 ? 16.194  -27.059 30.589 1.000 16.221 0 161 TYR   B CG  1 ? 
ATOM   3606 C CD1 . TYR   B 1 161 ? 16.549  -28.146 29.800 1.000 16.828 0 161 TYR   B CD1 1 ? 
ATOM   3607 C CD2 . TYR   B 1 161 ? 17.076  -25.978 30.631 1.000 16.660 0 161 TYR   B CD2 1 ? 
ATOM   3608 C CE1 . TYR   B 1 161 ? 17.709  -28.147 29.044 1.000 17.290 0 161 TYR   B CE1 1 ? 
ATOM   3609 C CE2 . TYR   B 1 161 ? 18.242  -25.959 29.882 1.000 17.024 0 161 TYR   B CE2 1 ? 
ATOM   3610 C CZ  . TYR   B 1 161 ? 18.562  -27.046 29.083 1.000 18.662 0 161 TYR   B CZ  1 ? 
ATOM   3611 O OH  . TYR   B 1 161 ? 19.733  -27.025 28.368 1.000 16.275 0 161 TYR   B OH  1 ? 
ATOM   3612 N N   . MET   B 1 162 ? 17.194  -27.705 33.588 1.000 13.873 0 162 MET   B N   1 ? 
ATOM   3613 C CA  . MET   B 1 162 ? 18.410  -27.102 34.105 1.000 14.309 0 162 MET   B CA  1 ? 
ATOM   3614 C C   . MET   B 1 162 ? 19.514  -27.334 33.088 1.000 13.746 0 162 MET   B C   1 ? 
ATOM   3615 O O   . MET   B 1 162 ? 19.650  -28.452 32.604 1.000 13.875 0 162 MET   B O   1 ? 
ATOM   3616 C CB  . MET   B 1 162 ? 18.855  -27.703 35.434 1.000 15.177 0 162 MET   B CB  1 ? 
ATOM   3617 C CG  . MET   B 1 162 ? 20.094  -27.027 35.993 1.000 16.901 0 162 MET   B CG  1 ? 
ATOM   3618 S SD  . MET   B 1 162 ? 20.529  -27.632 37.645 1.000 21.348 0 162 MET   B SD  1 ? 
ATOM   3619 C CE  . MET   B 1 162 ? 19.896  -26.249 38.600 1.000 18.948 0 162 MET   B CE  1 ? 
ATOM   3620 N N   . HIS   B 1 163 ? 20.298  -26.278 32.834 1.000 13.000 0 163 HIS   B N   1 ? 
ATOM   3621 C CA  . HIS   B 1 163 ? 21.260  -26.227 31.742 1.000 13.936 0 163 HIS   B CA  1 ? 
ATOM   3622 C C   . HIS   B 1 163 ? 22.623  -26.826 32.123 1.000 13.428 0 163 HIS   B C   1 ? 
ATOM   3623 O O   . HIS   B 1 163 ? 23.222  -26.445 33.133 1.000 12.542 0 163 HIS   B O   1 ? 
ATOM   3624 C CB  . HIS   B 1 163 ? 21.405  -24.786 31.240 1.000 12.840 0 163 HIS   B CB  1 ? 
ATOM   3625 C CG  . HIS   B 1 163 ? 22.353  -24.719 30.080 1.000 13.594 0 163 HIS   B CG  1 ? 
ATOM   3626 N ND1 . HIS   B 1 163 ? 22.120  -25.430 28.921 1.000 11.786 0 163 HIS   B ND1 1 ? 
ATOM   3627 C CD2 . HIS   B 1 163 ? 23.537  -24.097 29.903 1.000 12.494 0 163 HIS   B CD2 1 ? 
ATOM   3628 C CE1 . HIS   B 1 163 ? 23.130  -25.253 28.097 1.000 11.825 0 163 HIS   B CE1 1 ? 
ATOM   3629 N NE2 . HIS   B 1 163 ? 23.999  -24.457 28.668 1.000 11.921 0 163 HIS   B NE2 1 ? 
ATOM   3630 N N   . HIS   B 1 164 ? 23.134  -27.718 31.254 1.000 13.513 0 164 HIS   B N   1 ? 
ATOM   3631 C CA  . HIS   B 1 164 ? 24.415  -28.378 31.471 1.000 13.496 0 164 HIS   B CA  1 ? 
ATOM   3632 C C   . HIS   B 1 164 ? 25.423  -28.183 30.334 1.000 14.347 0 164 HIS   B C   1 ? 
ATOM   3633 O O   . HIS   B 1 164 ? 26.624  -28.158 30.599 1.000 12.961 0 164 HIS   B O   1 ? 
ATOM   3634 C CB  . HIS   B 1 164 ? 24.239  -29.885 31.690 1.000 13.848 0 164 HIS   B CB  1 ? 
ATOM   3635 C CG  . HIS   B 1 164 ? 23.569  -30.275 32.955 1.000 13.485 0 164 HIS   B CG  1 ? 
ATOM   3636 N ND1 . HIS   B 1 164 ? 24.209  -30.930 33.988 1.000 13.518 0 164 HIS   B ND1 1 ? 
ATOM   3637 C CD2 . HIS   B 1 164 ? 22.304  -30.081 33.353 1.000 13.992 0 164 HIS   B CD2 1 ? 
ATOM   3638 C CE1 . HIS   B 1 164 ? 23.336  -31.158 34.961 1.000 12.998 0 164 HIS   B CE1 1 ? 
ATOM   3639 N NE2 . HIS   B 1 164 ? 22.162  -30.643 34.599 1.000 13.785 0 164 HIS   B NE2 1 ? 
ATOM   3640 N N   . MET   B 1 165 ? 24.986  -28.102 29.068 1.000 16.894 0 165 MET   B N   1 ? 
ATOM   3641 C CA  . MET   B 1 165 ? 25.970  -28.199 28.002 1.000 20.306 0 165 MET   B CA  1 ? 
ATOM   3642 C C   . MET   B 1 165 ? 25.502  -27.641 26.656 1.000 19.347 0 165 MET   B C   1 ? 
ATOM   3643 O O   . MET   B 1 165 ? 24.309  -27.598 26.334 1.000 18.792 0 165 MET   B O   1 ? 
ATOM   3644 C CB  . MET   B 1 165 ? 26.408  -29.659 27.810 1.000 23.011 0 165 MET   B CB  1 ? 
ATOM   3645 C CG  . MET   B 1 165 ? 25.328  -30.603 27.398 1.000 27.249 0 165 MET   B CG  1 ? 
ATOM   3646 S SD  . MET   B 1 165 ? 25.963  -32.320 27.347 1.000 36.852 0 165 MET   B SD  1 ? 
ATOM   3647 C CE  . MET   B 1 165 ? 25.414  -32.757 25.708 1.000 38.536 0 165 MET   B CE  1 ? 
ATOM   3648 N N   . GLU   B 1 166 ? 26.510  -27.276 25.856 1.000 18.711 0 166 GLU   B N   1 ? 
ATOM   3649 C CA  . GLU   B 1 166 ? 26.326  -26.975 24.451 1.000 20.765 0 166 GLU   B CA  1 ? 
ATOM   3650 C C   . GLU   B 1 166 ? 26.827  -28.128 23.588 1.000 21.645 0 166 GLU   B C   1 ? 
ATOM   3651 O O   . GLU   B 1 166 ? 27.764  -28.844 23.961 1.000 18.277 0 166 GLU   B O   1 ? 
ATOM   3652 C CB  . GLU   B 1 166 ? 27.040  -25.689 24.061 1.000 23.279 0 166 GLU   B CB  1 ? 
ATOM   3653 C CG  . GLU   B 1 166 ? 28.517  -25.672 24.358 1.000 26.605 0 166 GLU   B CG  1 ? 
ATOM   3654 C CD  . GLU   B 1 166 ? 29.268  -24.555 23.640 1.000 30.271 0 166 GLU   B CD  1 ? 
ATOM   3655 O OE1 . GLU   B 1 166 ? 28.621  -23.773 22.868 1.000 28.683 0 166 GLU   B OE1 1 ? 
ATOM   3656 O OE2 . GLU   B 1 166 ? 30.502  -24.466 23.856 1.000 34.216 0 166 GLU   B OE2 1 ? 
ATOM   3657 N N   . LEU   B 1 167 ? 26.175  -28.258 22.428 1.000 21.909 0 167 LEU   B N   1 ? 
ATOM   3658 C CA  . LEU   B 1 167 ? 26.469  -29.275 21.435 1.000 23.366 0 167 LEU   B CA  1 ? 
ATOM   3659 C C   . LEU   B 1 167 ? 26.890  -28.599 20.128 1.000 25.766 0 167 LEU   B C   1 ? 
ATOM   3660 O O   . LEU   B 1 167 ? 26.616  -27.411 19.915 1.000 22.537 0 167 LEU   B O   1 ? 
ATOM   3661 C CB  . LEU   B 1 167 ? 25.210  -30.119 21.225 1.000 23.020 0 167 LEU   B CB  1 ? 
ATOM   3662 C CG  . LEU   B 1 167 ? 24.791  -30.972 22.418 1.000 24.195 0 167 LEU   B CG  1 ? 
ATOM   3663 C CD1 . LEU   B 1 167 ? 23.379  -31.480 22.226 1.000 26.362 0 167 LEU   B CD1 1 ? 
ATOM   3664 C CD2 . LEU   B 1 167 ? 25.736  -32.140 22.613 1.000 26.118 0 167 LEU   B CD2 1 ? 
ATOM   3665 N N   . PRO   B 1 168 ? 27.514  -29.351 19.187 1.000 26.997 0 168 PRO   B N   1 ? 
ATOM   3666 C CA  . PRO   B 1 168 ? 27.861  -28.788 17.881 1.000 31.251 0 168 PRO   B CA  1 ? 
ATOM   3667 C C   . PRO   B 1 168 ? 26.545  -28.413 17.193 1.000 32.376 0 168 PRO   B C   1 ? 
ATOM   3668 O O   . PRO   B 1 168 ? 25.519  -29.048 17.419 1.000 37.286 0 168 PRO   B O   1 ? 
ATOM   3669 C CB  . PRO   B 1 168 ? 28.662  -29.890 17.160 1.000 30.008 0 168 PRO   B CB  1 ? 
ATOM   3670 C CG  . PRO   B 1 168 ? 28.836  -31.017 18.178 1.000 28.348 0 168 PRO   B CG  1 ? 
ATOM   3671 C CD  . PRO   B 1 168 ? 27.838  -30.785 19.294 1.000 26.053 0 168 PRO   B CD  1 ? 
ATOM   3672 N N   . THR   B 1 169 ? 26.571  -27.327 16.419 1.000 35.532 0 169 THR   B N   1 ? 
ATOM   3673 C CA  . THR   B 1 169 ? 25.385  -26.731 15.818 1.000 36.293 0 169 THR   B CA  1 ? 
ATOM   3674 C C   . THR   B 1 169 ? 24.917  -25.550 16.662 1.000 30.717 0 169 THR   B C   1 ? 
ATOM   3675 O O   . THR   B 1 169 ? 24.069  -24.790 16.219 1.000 34.031 0 169 THR   B O   1 ? 
ATOM   3676 C CB  . THR   B 1 169 ? 24.244  -27.738 15.588 1.000 44.538 0 169 THR   B CB  1 ? 
ATOM   3677 O OG1 . THR   B 1 169 ? 24.755  -28.802 14.784 1.000 46.212 0 169 THR   B OG1 1 ? 
ATOM   3678 C CG2 . THR   B 1 169 ? 23.041  -27.152 14.876 1.000 51.081 0 169 THR   B CG2 1 ? 
ATOM   3679 N N   . GLY   B 1 170 ? 25.452  -25.388 17.876 1.000 25.649 0 170 GLY   B N   1 ? 
ATOM   3680 C CA  . GLY   B 1 170 ? 25.023  -24.297 18.740 1.000 24.533 0 170 GLY   B CA  1 ? 
ATOM   3681 C C   . GLY   B 1 170 ? 23.641  -24.507 19.371 1.000 21.309 0 170 GLY   B C   1 ? 
ATOM   3682 O O   . GLY   B 1 170 ? 22.914  -23.551 19.561 1.000 22.578 0 170 GLY   B O   1 ? 
ATOM   3683 N N   . VAL   B 1 171 ? 23.294  -25.753 19.697 1.000 18.453 0 171 VAL   B N   1 ? 
ATOM   3684 C CA  . VAL   B 1 171 ? 22.079  -26.082 20.424 1.000 17.148 0 171 VAL   B CA  1 ? 
ATOM   3685 C C   . VAL   B 1 171 ? 22.523  -26.608 21.786 1.000 14.921 0 171 VAL   B C   1 ? 
ATOM   3686 O O   . VAL   B 1 171 ? 23.718  -26.713 22.036 1.000 13.510 0 171 VAL   B O   1 ? 
ATOM   3687 C CB  . VAL   B 1 171 ? 21.195  -27.085 19.646 1.000 18.312 0 171 VAL   B CB  1 ? 
ATOM   3688 C CG1 . VAL   B 1 171 ? 20.725  -26.522 18.304 1.000 18.853 0 171 VAL   B CG1 1 ? 
ATOM   3689 C CG2 . VAL   B 1 171 ? 21.870  -28.423 19.454 1.000 18.462 0 171 VAL   B CG2 1 ? 
ATOM   3690 N N   . HIS   B 1 172 ? 21.565  -26.915 22.654 1.000 14.401 0 172 HIS   B N   1 ? 
ATOM   3691 C CA  . HIS   B 1 172 ? 21.839  -27.112 24.071 1.000 13.897 0 172 HIS   B CA  1 ? 
ATOM   3692 C C   . HIS   B 1 172 ? 21.115  -28.322 24.651 1.000 13.916 0 172 HIS   B C   1 ? 
ATOM   3693 O O   . HIS   B 1 172 ? 20.077  -28.772 24.153 1.000 12.943 0 172 HIS   B O   1 ? 
ATOM   3694 C CB  . HIS   B 1 172 ? 21.468  -25.847 24.831 1.000 14.054 0 172 HIS   B CB  1 ? 
ATOM   3695 C CG  . HIS   B 1 172 ? 22.217  -24.674 24.315 1.000 15.255 0 172 HIS   B CG  1 ? 
ATOM   3696 N ND1 . HIS   B 1 172 ? 21.683  -23.821 23.383 1.000 13.538 0 172 HIS   B ND1 1 ? 
ATOM   3697 C CD2 . HIS   B 1 172 ? 23.501  -24.256 24.550 1.000 15.935 0 172 HIS   B CD2 1 ? 
ATOM   3698 C CE1 . HIS   B 1 172 ? 22.593  -22.899 23.098 1.000 16.203 0 172 HIS   B CE1 1 ? 
ATOM   3699 N NE2 . HIS   B 1 172 ? 23.698  -23.130 23.812 1.000 15.590 0 172 HIS   B NE2 1 ? 
ATOM   3700 N N   . ALA   B 1 173 ? 21.719  -28.852 25.724 1.000 14.512 0 173 ALA   B N   1 ? 
ATOM   3701 C CA  . ALA   B 1 173 ? 21.180  -30.002 26.431 1.000 15.327 0 173 ALA   B CA  1 ? 
ATOM   3702 C C   . ALA   B 1 173 ? 21.316  -29.801 27.928 1.000 15.196 0 173 ALA   B C   1 ? 
ATOM   3703 O O   . ALA   B 1 173 ? 22.284  -29.212 28.422 1.000 14.006 0 173 ALA   B O   1 ? 
ATOM   3704 C CB  . ALA   B 1 173 ? 21.893  -31.265 26.015 1.000 17.164 0 173 ALA   B CB  1 ? 
ATOM   3705 N N   . GLY   B 1 174 ? 20.331  -30.358 28.632 1.000 15.141 0 174 GLY   B N   1 ? 
ATOM   3706 C CA  . GLY   B 1 174 ? 20.300  -30.301 30.073 1.000 14.367 0 174 GLY   B CA  1 ? 
ATOM   3707 C C   . GLY   B 1 174 ? 19.346  -31.352 30.608 1.000 14.968 0 174 GLY   B C   1 ? 
ATOM   3708 O O   . GLY   B 1 174 ? 18.948  -32.260 29.882 1.000 15.226 0 174 GLY   B O   1 ? 
ATOM   3709 N N   . THR   B 1 175 ? 18.961  -31.176 31.873 1.000 14.937 0 175 THR   B N   1 ? 
ATOM   3710 C CA  . THR   B 1 175 ? 18.310  -32.231 32.630 1.000 15.174 0 175 THR   B CA  1 ? 
ATOM   3711 C C   . THR   B 1 175 ? 17.014  -31.675 33.182 1.000 14.493 0 175 THR   B C   1 ? 
ATOM   3712 O O   . THR   B 1 175 ? 16.792  -30.480 33.098 1.000 14.018 0 175 THR   B O   1 ? 
ATOM   3713 C CB  . THR   B 1 175 ? 19.176  -32.731 33.789 1.000 15.166 0 175 THR   B CB  1 ? 
ATOM   3714 O OG1 . THR   B 1 175 ? 19.260  -31.664 34.737 1.000 17.232 0 175 THR   B OG1 1 ? 
ATOM   3715 C CG2 . THR   B 1 175 ? 20.550  -33.175 33.364 1.000 14.825 0 175 THR   B CG2 1 ? 
ATOM   3716 N N   . ASP   B 1 176 ? 16.157  -32.551 33.696 1.000 14.417 0 176 ASP   B N   1 ? 
ATOM   3717 C CA  . ASP   B 1 176 ? 15.098  -32.090 34.579 1.000 15.781 0 176 ASP   B CA  1 ? 
ATOM   3718 C C   . ASP   B 1 176 ? 15.694  -31.848 35.976 1.000 15.412 0 176 ASP   B C   1 ? 
ATOM   3719 O O   . ASP   B 1 176 ? 16.908  -31.986 36.209 1.000 15.327 0 176 ASP   B O   1 ? 
ATOM   3720 C CB  . ASP   B 1 176 ? 13.916  -33.053 34.516 1.000 17.055 0 176 ASP   B CB  1 ? 
ATOM   3721 C CG  . ASP   B 1 176 ? 14.180  -34.476 35.000 1.000 18.632 0 176 ASP   B CG  1 ? 
ATOM   3722 O OD1 . ASP   B 1 176 ? 15.166  -34.701 35.789 1.000 17.476 0 176 ASP   B OD1 1 ? 
ATOM   3723 O OD2 . ASP   B 1 176 ? 13.402  -35.357 34.576 1.000 18.579 0 176 ASP   B OD2 1 ? 
ATOM   3724 N N   . LEU   B 1 177 ? 14.843  -31.479 36.916 1.000 15.490 0 177 LEU   B N   1 ? 
ATOM   3725 C CA  . LEU   B 1 177 ? 15.326  -31.091 38.232 1.000 17.729 0 177 LEU   B CA  1 ? 
ATOM   3726 C C   . LEU   B 1 177 ? 15.545  -32.303 39.140 1.000 19.031 0 177 LEU   B C   1 ? 
ATOM   3727 O O   . LEU   B 1 177 ? 16.086  -32.148 40.229 1.000 18.645 0 177 LEU   B O   1 ? 
ATOM   3728 C CB  . LEU   B 1 177 ? 14.373  -30.074 38.852 1.000 17.854 0 177 LEU   B CB  1 ? 
ATOM   3729 C CG  . LEU   B 1 177 ? 14.776  -28.620 38.646 1.000 19.772 0 177 LEU   B CG  1 ? 
ATOM   3730 C CD1 . LEU   B 1 177 ? 16.140  -28.362 39.248 1.000 20.295 0 177 LEU   B CD1 1 ? 
ATOM   3731 C CD2 . LEU   B 1 177 ? 14.769  -28.247 37.165 1.000 20.798 0 177 LEU   B CD2 1 ? 
ATOM   3732 N N   . GLU   B 1 178 ? 15.252  -33.512 38.649 1.000 19.445 0 178 GLU   B N   1 ? 
ATOM   3733 C CA  . GLU   B 1 178 ? 15.709  -34.718 39.323 1.000 21.337 0 178 GLU   B CA  1 ? 
ATOM   3734 C C   . GLU   B 1 178 ? 17.032  -35.158 38.712 1.000 20.438 0 178 GLU   B C   1 ? 
ATOM   3735 O O   . GLU   B 1 178 ? 17.631  -36.149 39.131 1.000 21.262 0 178 GLU   B O   1 ? 
ATOM   3736 C CB  . GLU   B 1 178 ? 14.659  -35.827 39.222 1.000 24.213 0 178 GLU   B CB  1 ? 
ATOM   3737 C CG  . GLU   B 1 178 ? 13.407  -35.520 40.021 1.000 28.649 0 178 GLU   B CG  1 ? 
ATOM   3738 C CD  . GLU   B 1 178 ? 12.296  -36.551 39.870 1.000 37.452 0 178 GLU   B CD  1 ? 
ATOM   3739 O OE1 . GLU   B 1 178 ? 11.977  -36.904 38.706 1.000 39.719 0 178 GLU   B OE1 1 ? 
ATOM   3740 O OE2 . GLU   B 1 178 ? 11.721  -36.981 40.913 1.000 41.417 0 178 GLU   B OE2 1 ? 
ATOM   3741 N N   . GLY   B 1 179 ? 17.466  -34.446 37.674 1.000 18.809 0 179 GLY   B N   1 ? 
ATOM   3742 C CA  . GLY   B 1 179 ? 18.829  -34.585 37.204 1.000 18.648 0 179 GLY   B CA  1 ? 
ATOM   3743 C C   . GLY   B 1 179 ? 18.973  -35.661 36.141 1.000 16.874 0 179 GLY   B C   1 ? 
ATOM   3744 O O   . GLY   B 1 179 ? 20.074  -36.110 35.868 1.000 17.777 0 179 GLY   B O   1 ? 
ATOM   3745 N N   . ASN   B 1 180 ? 17.863  -36.016 35.505 1.000 17.050 0 180 ASN   B N   1 ? 
ATOM   3746 C CA  . ASN   B 1 180 ? 17.891  -36.913 34.367 1.000 16.033 0 180 ASN   B CA  1 ? 
ATOM   3747 C C   . ASN   B 1 180 ? 17.923  -36.078 33.109 1.000 14.954 0 180 ASN   B C   1 ? 
ATOM   3748 O O   . ASN   B 1 180 ? 17.067  -35.223 32.939 1.000 14.554 0 180 ASN   B O   1 ? 
ATOM   3749 C CB  . ASN   B 1 180 ? 16.694  -37.854 34.376 1.000 16.030 0 180 ASN   B CB  1 ? 
ATOM   3750 C CG  . ASN   B 1 180 ? 16.727  -38.760 35.587 1.000 18.279 0 180 ASN   B CG  1 ? 
ATOM   3751 O OD1 . ASN   B 1 180 ? 15.794  -38.791 36.373 1.000 21.530 0 180 ASN   B OD1 1 ? 
ATOM   3752 N ND2 . ASN   B 1 180 ? 17.805  -39.487 35.764 1.000 19.329 0 180 ASN   B ND2 1 ? 
ATOM   3753 N N   . PHE   B 1 181 ? 18.898  -36.368 32.239 1.000 16.031 0 181 PHE   B N   1 ? 
ATOM   3754 C CA  . PHE   B 1 181 ? 19.052  -35.698 30.954 1.000 16.870 0 181 PHE   B CA  1 ? 
ATOM   3755 C C   . PHE   B 1 181 ? 17.816  -35.910 30.079 1.000 17.076 0 181 PHE   B C   1 ? 
ATOM   3756 O O   . PHE   B 1 181 ? 17.212  -36.975 30.072 1.000 15.033 0 181 PHE   B O   1 ? 
ATOM   3757 C CB  . PHE   B 1 181 ? 20.300  -36.186 30.202 1.000 16.930 0 181 PHE   B CB  1 ? 
ATOM   3758 C CG  . PHE   B 1 181 ? 21.484  -35.284 30.401 1.000 16.966 0 181 PHE   B CG  1 ? 
ATOM   3759 C CD1 . PHE   B 1 181 ? 21.626  -34.124 29.653 1.000 17.963 0 181 PHE   B CD1 1 ? 
ATOM   3760 C CD2 . PHE   B 1 181 ? 22.368  -35.511 31.443 1.000 17.224 0 181 PHE   B CD2 1 ? 
ATOM   3761 C CE1 . PHE   B 1 181 ? 22.698  -33.273 29.872 1.000 17.471 0 181 PHE   B CE1 1 ? 
ATOM   3762 C CE2 . PHE   B 1 181 ? 23.426  -34.654 31.674 1.000 17.553 0 181 PHE   B CE2 1 ? 
ATOM   3763 C CZ  . PHE   B 1 181 ? 23.601  -33.541 30.881 1.000 17.017 0 181 PHE   B CZ  1 ? 
ATOM   3764 N N   . TYR   B 1 182 ? 17.423  -34.846 29.377 1.000 17.014 0 182 TYR   B N   1 ? 
ATOM   3765 C CA  . TYR   B 1 182 ? 16.606  -34.999 28.190 1.000 16.959 0 182 TYR   B CA  1 ? 
ATOM   3766 C C   . TYR   B 1 182 ? 17.509  -35.544 27.088 1.000 16.337 0 182 TYR   B C   1 ? 
ATOM   3767 O O   . TYR   B 1 182 ? 18.577  -35.001 26.808 1.000 15.780 0 182 TYR   B O   1 ? 
ATOM   3768 C CB  . TYR   B 1 182 ? 15.936  -33.672 27.842 1.000 15.919 0 182 TYR   B CB  1 ? 
ATOM   3769 C CG  . TYR   B 1 182 ? 14.909  -33.195 28.862 1.000 15.481 0 182 TYR   B CG  1 ? 
ATOM   3770 C CD1 . TYR   B 1 182 ? 13.608  -33.699 28.885 1.000 15.066 0 182 TYR   B CD1 1 ? 
ATOM   3771 C CD2 . TYR   B 1 182 ? 15.232  -32.185 29.772 1.000 15.534 0 182 TYR   B CD2 1 ? 
ATOM   3772 C CE1 . TYR   B 1 182 ? 12.667  -33.213 29.775 1.000 14.941 0 182 TYR   B CE1 1 ? 
ATOM   3773 C CE2 . TYR   B 1 182 ? 14.305  -31.699 30.675 1.000 14.459 0 182 TYR   B CE2 1 ? 
ATOM   3774 C CZ  . TYR   B 1 182 ? 13.020  -32.214 30.675 1.000 14.974 0 182 TYR   B CZ  1 ? 
ATOM   3775 O OH  . TYR   B 1 182 ? 12.123  -31.704 31.561 1.000 14.463 0 182 TYR   B OH  1 ? 
ATOM   3776 N N   . GLY   B 1 183 ? 17.085  -36.661 26.498 1.000 17.658 0 183 GLY   B N   1 ? 
ATOM   3777 C CA  . GLY   B 1 183 ? 17.846  -37.298 25.439 1.000 19.948 0 183 GLY   B CA  1 ? 
ATOM   3778 C C   . GLY   B 1 183 ? 19.015  -38.112 25.985 1.000 23.228 0 183 GLY   B C   1 ? 
ATOM   3779 O O   . GLY   B 1 183 ? 19.184  -38.213 27.193 1.000 23.483 0 183 GLY   B O   1 ? 
ATOM   3780 N N   . PRO   B 1 184 ? 19.857  -38.695 25.102 1.000 26.865 0 184 PRO   B N   1 ? 
ATOM   3781 C CA  . PRO   B 1 184 ? 20.903  -39.636 25.520 1.000 28.628 0 184 PRO   B CA  1 ? 
ATOM   3782 C C   . PRO   B 1 184 ? 22.233  -38.995 25.917 1.000 27.657 0 184 PRO   B C   1 ? 
ATOM   3783 O O   . PRO   B 1 184 ? 23.262  -39.639 25.844 1.000 32.265 0 184 PRO   B O   1 ? 
ATOM   3784 C CB  . PRO   B 1 184 ? 21.085  -40.441 24.220 1.000 30.323 0 184 PRO   B CB  1 ? 
ATOM   3785 C CG  . PRO   B 1 184 ? 20.960  -39.361 23.143 1.000 30.697 0 184 PRO   B CG  1 ? 
ATOM   3786 C CD  . PRO   B 1 184 ? 19.802  -38.515 23.637 1.000 27.800 0 184 PRO   B CD  1 ? 
ATOM   3787 N N   . PHE   B 1 185 ? 22.219  -37.729 26.341 1.000 23.736 0 185 PHE   B N   1 ? 
ATOM   3788 C CA  . PHE   B 1 185 ? 23.447  -36.990 26.573 1.000 22.986 0 185 PHE   B CA  1 ? 
ATOM   3789 C C   . PHE   B 1 185 ? 23.969  -37.255 27.982 1.000 22.172 0 185 PHE   B C   1 ? 
ATOM   3790 O O   . PHE   B 1 185 ? 23.182  -37.570 28.855 1.000 20.454 0 185 PHE   B O   1 ? 
ATOM   3791 C CB  . PHE   B 1 185 ? 23.174  -35.503 26.361 1.000 22.824 0 185 PHE   B CB  1 ? 
ATOM   3792 C CG  . PHE   B 1 185 ? 22.556  -35.229 25.019 1.000 23.598 0 185 PHE   B CG  1 ? 
ATOM   3793 C CD1 . PHE   B 1 185 ? 23.298  -35.396 23.859 1.000 25.408 0 185 PHE   B CD1 1 ? 
ATOM   3794 C CD2 . PHE   B 1 185 ? 21.239  -34.835 24.915 1.000 23.071 0 185 PHE   B CD2 1 ? 
ATOM   3795 C CE1 . PHE   B 1 185 ? 22.731  -35.135 22.619 1.000 26.689 0 185 PHE   B CE1 1 ? 
ATOM   3796 C CE2 . PHE   B 1 185 ? 20.661  -34.615 23.674 1.000 24.811 0 185 PHE   B CE2 1 ? 
ATOM   3797 C CZ  . PHE   B 1 185 ? 21.408  -34.760 22.528 1.000 26.015 0 185 PHE   B CZ  1 ? 
ATOM   3798 N N   . VAL   B 1 186 ? 25.285  -37.085 28.190 1.000 22.352 0 186 VAL   B N   1 ? 
ATOM   3799 C CA  . VAL   B 1 186 ? 25.921  -37.374 29.477 1.000 22.565 0 186 VAL   B CA  1 ? 
ATOM   3800 C C   . VAL   B 1 186 ? 26.767  -36.185 29.924 1.000 21.645 0 186 VAL   B C   1 ? 
ATOM   3801 O O   . VAL   B 1 186 ? 27.215  -35.387 29.098 1.000 18.376 0 186 VAL   B O   1 ? 
ATOM   3802 C CB  . VAL   B 1 186 ? 26.785  -38.656 29.435 1.000 23.479 0 186 VAL   B CB  1 ? 
ATOM   3803 C CG1 . VAL   B 1 186 ? 25.920  -39.908 29.340 1.000 22.983 0 186 VAL   B CG1 1 ? 
ATOM   3804 C CG2 . VAL   B 1 186 ? 27.840  -38.627 28.332 1.000 22.881 0 186 VAL   B CG2 1 ? 
ATOM   3805 N N   . ASP   B 1 187 ? 27.002  -36.086 31.240 1.000 23.052 0 187 ASP   B N   1 ? 
ATOM   3806 C CA  . ASP   B 1 187 ? 27.689  -34.920 31.775 1.000 23.041 0 187 ASP   B CA  1 ? 
ATOM   3807 C C   . ASP   B 1 187 ? 29.176  -35.218 31.951 1.000 25.771 0 187 ASP   B C   1 ? 
ATOM   3808 O O   . ASP   B 1 187 ? 29.712  -35.192 33.060 1.000 25.731 0 187 ASP   B O   1 ? 
ATOM   3809 C CB  . ASP   B 1 187 ? 27.020  -34.329 33.021 1.000 21.090 0 187 ASP   B CB  1 ? 
ATOM   3810 C CG  . ASP   B 1 187 ? 26.947  -35.228 34.235 1.000 20.637 0 187 ASP   B CG  1 ? 
ATOM   3811 O OD1 . ASP   B 1 187 ? 27.164  -36.433 34.084 1.000 18.881 0 187 ASP   B OD1 1 ? 
ATOM   3812 O OD2 . ASP   B 1 187 ? 26.740  -34.685 35.345 1.000 20.702 0 187 ASP   B OD2 1 ? 
ATOM   3813 N N   . ARG   B 1 188 ? 29.854  -35.337 30.805 1.000 30.580 0 188 ARG   B N   1 ? 
ATOM   3814 C CA  . ARG   B 1 188 ? 31.304  -35.394 30.755 1.000 34.297 0 188 ARG   B CA  1 ? 
ATOM   3815 C C   . ARG   B 1 188 ? 31.793  -34.803 29.434 1.000 33.832 0 188 ARG   B C   1 ? 
ATOM   3816 O O   . ARG   B 1 188 ? 31.053  -34.775 28.455 1.000 31.503 0 188 ARG   B O   1 ? 
ATOM   3817 C CB  . ARG   B 1 188 ? 31.769  -36.848 30.870 1.000 35.835 0 188 ARG   B CB  1 ? 
ATOM   3818 C CG  . ARG   B 1 188 ? 31.530  -37.648 29.602 1.000 37.836 0 188 ARG   B CG  1 ? 
ATOM   3819 C CD  . ARG   B 1 188 ? 31.928  -39.095 29.767 1.000 41.798 0 188 ARG   B CD  1 ? 
ATOM   3820 N NE  . ARG   B 1 188 ? 30.940  -39.757 30.590 1.000 42.664 0 188 ARG   B NE  1 ? 
ATOM   3821 C CZ  . ARG   B 1 188 ? 30.128  -40.726 30.183 1.000 41.292 0 188 ARG   B CZ  1 ? 
ATOM   3822 N NH1 . ARG   B 1 188 ? 29.093  -41.073 30.932 1.000 38.258 0 188 ARG   B NH1 1 ? 
ATOM   3823 N NH2 . ARG   B 1 188 ? 30.310  -41.297 29.006 1.000 41.813 0 188 ARG   B NH2 1 ? 
ATOM   3824 N N   . GLN   B 1 189 ? 33.066  -34.400 29.424 1.000 36.238 0 189 GLN   B N   1 ? 
ATOM   3825 C CA  . GLN   B 1 189 ? 33.759  -33.915 28.239 1.000 40.398 0 189 GLN   B CA  1 ? 
ATOM   3826 C C   . GLN   B 1 189 ? 33.967  -35.070 27.262 1.000 42.350 0 189 GLN   B C   1 ? 
ATOM   3827 O O   . GLN   B 1 189 ? 34.891  -35.871 27.413 1.000 43.623 0 189 GLN   B O   1 ? 
ATOM   3828 C CB  . GLN   B 1 189 ? 35.103  -33.309 28.650 1.000 42.218 0 189 GLN   B CB  1 ? 
ATOM   3829 C CG  . GLN   B 1 189 ? 35.904  -32.726 27.494 1.000 47.722 0 189 GLN   B CG  1 ? 
ATOM   3830 C CD  . GLN   B 1 189 ? 37.127  -32.005 28.005 1.000 51.659 0 189 GLN   B CD  1 ? 
ATOM   3831 O OE1 . GLN   B 1 189 ? 37.545  -32.182 29.150 1.000 55.825 0 189 GLN   B OE1 1 ? 
ATOM   3832 N NE2 . GLN   B 1 189 ? 37.721  -31.191 27.145 1.000 53.370 0 189 GLN   B NE2 1 ? 
ATOM   3833 N N   . THR   B 1 190 ? 33.076  -35.169 26.280 1.000 42.234 0 190 THR   B N   1 ? 
ATOM   3834 C CA  . THR   B 1 190 ? 33.129  -36.249 25.313 1.000 46.394 0 190 THR   B CA  1 ? 
ATOM   3835 C C   . THR   B 1 190 ? 32.382  -35.795 24.063 1.000 51.092 0 190 THR   B C   1 ? 
ATOM   3836 O O   . THR   B 1 190 ? 31.453  -34.993 24.153 1.000 60.777 0 190 THR   B O   1 ? 
ATOM   3837 C CB  . THR   B 1 190 ? 32.603  -37.553 25.933 1.000 46.508 0 190 THR   B CB  1 ? 
ATOM   3838 O OG1 . THR   B 1 190 ? 33.036  -38.644 25.125 1.000 43.621 0 190 THR   B OG1 1 ? 
ATOM   3839 C CG2 . THR   B 1 190 ? 31.095  -37.621 26.075 1.000 44.874 0 190 THR   B CG2 1 ? 
ATOM   3840 N N   . ALA   B 1 191 ? 32.813  -36.287 22.897 1.000 51.093 0 191 ALA   B N   1 ? 
ATOM   3841 C CA  . ALA   B 1 191 ? 32.194  -35.884 21.647 1.000 53.224 0 191 ALA   B CA  1 ? 
ATOM   3842 C C   . ALA   B 1 191 ? 30.750  -36.379 21.632 1.000 46.006 0 191 ALA   B C   1 ? 
ATOM   3843 O O   . ALA   B 1 191 ? 30.484  -37.580 21.714 1.000 42.954 0 191 ALA   B O   1 ? 
ATOM   3844 C CB  . ALA   B 1 191 ? 32.985  -36.385 20.463 1.000 56.951 0 191 ALA   B CB  1 ? 
ATOM   3845 N N   . GLN   B 1 192 ? 29.823  -35.419 21.580 1.000 40.837 0 192 GLN   B N   1 ? 
ATOM   3846 C CA  . GLN   B 1 192 ? 28.399  -35.723 21.594 1.000 37.911 0 192 GLN   B CA  1 ? 
ATOM   3847 C C   . GLN   B 1 192 ? 27.723  -34.879 20.530 1.000 32.634 0 192 GLN   B C   1 ? 
ATOM   3848 O O   . GLN   B 1 192 ? 28.167  -33.762 20.256 1.000 30.753 0 192 GLN   B O   1 ? 
ATOM   3849 C CB  . GLN   B 1 192 ? 27.765  -35.409 22.955 1.000 35.527 0 192 GLN   B CB  1 ? 
ATOM   3850 C CG  . GLN   B 1 192 ? 28.311  -36.250 24.093 1.000 32.767 0 192 GLN   B CG  1 ? 
ATOM   3851 C CD  . GLN   B 1 192 ? 27.618  -35.892 25.378 1.000 27.510 0 192 GLN   B CD  1 ? 
ATOM   3852 O OE1 . GLN   B 1 192 ? 26.466  -36.249 25.619 1.000 31.541 0 192 GLN   B OE1 1 ? 
ATOM   3853 N NE2 . GLN   B 1 192 ? 28.315  -35.150 26.209 1.000 25.578 0 192 GLN   B NE2 1 ? 
ATOM   3854 N N   . ALA   B 1 193 ? 26.653  -35.434 19.956 1.000 33.579 0 193 ALA   B N   1 ? 
ATOM   3855 C CA  . ALA   B 1 193 ? 25.953  -34.767 18.879 1.000 32.372 0 193 ALA   B CA  1 ? 
ATOM   3856 C C   . ALA   B 1 193 ? 24.464  -35.100 18.945 1.000 29.521 0 193 ALA   B C   1 ? 
ATOM   3857 O O   . ALA   B 1 193 ? 24.071  -36.210 19.274 1.000 28.888 0 193 ALA   B O   1 ? 
ATOM   3858 C CB  . ALA   B 1 193 ? 26.580  -35.141 17.553 1.000 33.566 0 193 ALA   B CB  1 ? 
ATOM   3859 N N   . ALA   B 1 194 ? 23.648  -34.102 18.605 1.000 31.050 0 194 ALA   B N   1 ? 
ATOM   3860 C CA  . ALA   B 1 194 ? 22.207  -34.262 18.484 1.000 31.340 0 194 ALA   B CA  1 ? 
ATOM   3861 C C   . ALA   B 1 194 ? 21.877  -35.081 17.244 1.000 30.174 0 194 ALA   B C   1 ? 
ATOM   3862 O O   . ALA   B 1 194 ? 22.545  -34.923 16.226 1.000 31.038 0 194 ALA   B O   1 ? 
ATOM   3863 C CB  . ALA   B 1 194 ? 21.573  -32.908 18.363 1.000 30.767 0 194 ALA   B CB  1 ? 
ATOM   3864 N N   . GLY   B 1 195 ? 20.822  -35.895 17.337 1.000 29.409 0 195 GLY   B N   1 ? 
ATOM   3865 C CA  . GLY   B 1 195 ? 20.234  -36.561 16.185 1.000 30.434 0 195 GLY   B CA  1 ? 
ATOM   3866 C C   . GLY   B 1 195 ? 19.621  -35.552 15.212 1.000 28.949 0 195 GLY   B C   1 ? 
ATOM   3867 O O   . GLY   B 1 195 ? 19.620  -34.345 15.455 1.000 25.075 0 195 GLY   B O   1 ? 
ATOM   3868 N N   . THR   B 1 196 ? 19.115  -36.063 14.096 1.000 27.468 0 196 THR   B N   1 ? 
ATOM   3869 C CA  . THR   B 1 196 ? 18.385  -35.246 13.142 1.000 29.327 0 196 THR   B CA  1 ? 
ATOM   3870 C C   . THR   B 1 196 ? 17.097  -34.773 13.802 1.000 26.243 0 196 THR   B C   1 ? 
ATOM   3871 O O   . THR   B 1 196 ? 16.414  -35.545 14.457 1.000 27.300 0 196 THR   B O   1 ? 
ATOM   3872 C CB  . THR   B 1 196 ? 18.067  -36.024 11.861 1.000 31.722 0 196 THR   B CB  1 ? 
ATOM   3873 O OG1 . THR   B 1 196 ? 19.295  -36.643 11.487 1.000 33.408 0 196 THR   B OG1 1 ? 
ATOM   3874 C CG2 . THR   B 1 196 ? 17.541  -35.154 10.737 1.000 31.810 0 196 THR   B CG2 1 ? 
ATOM   3875 N N   . ASP   B 1 197 ? 16.800  -33.488 13.646 1.000 26.035 0 197 ASP   B N   1 ? 
ATOM   3876 C CA  . ASP   B 1 197 ? 15.624  -32.927 14.269 1.000 26.794 0 197 ASP   B CA  1 ? 
ATOM   3877 C C   . ASP   B 1 197 ? 14.468  -33.008 13.276 1.000 26.670 0 197 ASP   B C   1 ? 
ATOM   3878 O O   . ASP   B 1 197 ? 14.684  -33.216 12.090 1.000 27.907 0 197 ASP   B O   1 ? 
ATOM   3879 C CB  . ASP   B 1 197 ? 15.888  -31.507 14.752 1.000 26.606 0 197 ASP   B CB  1 ? 
ATOM   3880 C CG  . ASP   B 1 197 ? 14.900  -31.053 15.811 1.000 24.688 0 197 ASP   B CG  1 ? 
ATOM   3881 O OD1 . ASP   B 1 197 ? 14.361  -31.921 16.511 1.000 23.282 0 197 ASP   B OD1 1 ? 
ATOM   3882 O OD2 . ASP   B 1 197 ? 14.692  -29.853 15.922 1.000 24.238 0 197 ASP   B OD2 1 ? 
ATOM   3883 N N   . THR   B 1 198 ? 13.247  -32.876 13.788 1.000 24.190 0 198 THR   B N   1 ? 
ATOM   3884 C CA  . THR   B 1 198 ? 12.056  -32.822 12.956 1.000 25.238 0 198 THR   B CA  1 ? 
ATOM   3885 C C   . THR   B 1 198 ? 11.241  -31.586 13.329 1.000 21.963 0 198 THR   B C   1 ? 
ATOM   3886 O O   . THR   B 1 198 ? 11.513  -30.935 14.340 1.000 20.305 0 198 THR   B O   1 ? 
ATOM   3887 C CB  . THR   B 1 198 ? 11.300  -34.148 13.088 1.000 28.595 0 198 THR   B CB  1 ? 
ATOM   3888 O OG1 . THR   B 1 198 ? 11.071  -34.371 14.473 1.000 26.737 0 198 THR   B OG1 1 ? 
ATOM   3889 C CG2 . THR   B 1 198 ? 12.079  -35.316 12.534 1.000 32.708 0 198 THR   B CG2 1 ? 
ATOM   3890 N N   . THR   B 1 199 ? 10.282  -31.238 12.466 1.000 20.281 0 199 THR   B N   1 ? 
ATOM   3891 C CA  . THR   B 1 199 ? 9.451   -30.062 12.654 1.000 17.466 0 199 THR   B CA  1 ? 
ATOM   3892 C C   . THR   B 1 199 ? 8.194   -30.474 13.427 1.000 16.315 0 199 THR   B C   1 ? 
ATOM   3893 O O   . THR   B 1 199 ? 7.613   -31.512 13.144 1.000 16.582 0 199 THR   B O   1 ? 
ATOM   3894 C CB  . THR   B 1 199 ? 9.143   -29.376 11.320 1.000 17.189 0 199 THR   B CB  1 ? 
ATOM   3895 O OG1 . THR   B 1 199 ? 10.357  -28.918 10.730 1.000 16.413 0 199 THR   B OG1 1 ? 
ATOM   3896 C CG2 . THR   B 1 199 ? 8.244   -28.172 11.496 1.000 17.595 0 199 THR   B CG2 1 ? 
ATOM   3897 N N   . ILE   B 1 200 ? 7.811   -29.677 14.437 1.000 15.979 0 200 ILE   B N   1 ? 
ATOM   3898 C CA  . ILE   B 1 200 ? 6.670   -29.981 15.304 1.000 15.243 0 200 ILE   B CA  1 ? 
ATOM   3899 C C   . ILE   B 1 200 ? 5.377   -29.528 14.614 1.000 13.915 0 200 ILE   B C   1 ? 
ATOM   3900 O O   . ILE   B 1 200 ? 4.900   -28.396 14.810 1.000 14.229 0 200 ILE   B O   1 ? 
ATOM   3901 C CB  . ILE   B 1 200 ? 6.833   -29.354 16.707 1.000 13.845 0 200 ILE   B CB  1 ? 
ATOM   3902 C CG1 . ILE   B 1 200 ? 8.198   -29.670 17.329 1.000 14.127 0 200 ILE   B CG1 1 ? 
ATOM   3903 C CG2 . ILE   B 1 200 ? 5.707   -29.831 17.617 1.000 14.369 0 200 ILE   B CG2 1 ? 
ATOM   3904 C CD1 . ILE   B 1 200 ? 8.666   -28.658 18.322 1.000 13.715 0 200 ILE   B CD1 1 ? 
ATOM   3905 N N   . THR   B 1 201 ? 4.828   -30.436 13.799 1.000 12.486 0 201 THR   B N   1 ? 
ATOM   3906 C CA  . THR   B 1 201 ? 3.708   -30.155 12.910 1.000 12.490 0 201 THR   B CA  1 ? 
ATOM   3907 C C   . THR   B 1 201 ? 2.548   -29.496 13.652 1.000 11.709 0 201 THR   B C   1 ? 
ATOM   3908 O O   . THR   B 1 201 ? 1.993   -28.490 13.194 1.000 12.080 0 201 THR   B O   1 ? 
ATOM   3909 C CB  . THR   B 1 201 ? 3.228   -31.443 12.223 1.000 13.139 0 201 THR   B CB  1 ? 
ATOM   3910 O OG1 . THR   B 1 201 ? 4.405   -31.984 11.633 1.000 12.947 0 201 THR   B OG1 1 ? 
ATOM   3911 C CG2 . THR   B 1 201 ? 2.193   -31.223 11.144 1.000 13.537 0 201 THR   B CG2 1 ? 
ATOM   3912 N N   . VAL   B 1 202 ? 2.202   -30.039 14.809 1.000 11.018 0 202 VAL   B N   1 ? 
ATOM   3913 C CA  . VAL   B 1 202 ? 1.035   -29.562 15.543 1.000 12.042 0 202 VAL   B CA  1 ? 
ATOM   3914 C C   . VAL   B 1 202 ? 1.216   -28.077 15.907 1.000 12.194 0 202 VAL   B C   1 ? 
ATOM   3915 O O   . VAL   B 1 202 ? 0.256   -27.292 15.846 1.000 12.656 0 202 VAL   B O   1 ? 
ATOM   3916 C CB  . VAL   B 1 202 ? 0.715   -30.434 16.778 1.000 12.200 0 202 VAL   B CB  1 ? 
ATOM   3917 C CG1 . VAL   B 1 202 ? 1.799   -30.362 17.849 1.000 11.965 0 202 VAL   B CG1 1 ? 
ATOM   3918 C CG2 . VAL   B 1 202 ? -0.639  -30.049 17.386 1.000 12.578 0 202 VAL   B CG2 1 ? 
ATOM   3919 N N   . ASN   B 1 203 ? 2.465   -27.706 16.235 1.000 11.734 0 203 ASN   B N   1 ? 
ATOM   3920 C CA  . ASN   B 1 203 ? 2.823   -26.339 16.594 1.000 11.577 0 203 ASN   B CA  1 ? 
ATOM   3921 C C   . ASN   B 1 203 ? 2.748   -25.423 15.369 1.000 11.166 0 203 ASN   B C   1 ? 
ATOM   3922 O O   . ASN   B 1 203 ? 2.363   -24.266 15.488 1.000 11.703 0 203 ASN   B O   1 ? 
ATOM   3923 C CB  . ASN   B 1 203 ? 4.216   -26.267 17.223 1.000 11.396 0 203 ASN   B CB  1 ? 
ATOM   3924 C CG  . ASN   B 1 203 ? 4.318   -26.793 18.639 1.000 11.663 0 203 ASN   B CG  1 ? 
ATOM   3925 O OD1 . ASN   B 1 203 ? 5.364   -26.649 19.273 1.000 12.748 0 203 ASN   B OD1 1 ? 
ATOM   3926 N ND2 . ASN   B 1 203 ? 3.267   -27.392 19.173 1.000 12.325 0 203 ASN   B ND2 1 ? 
ATOM   3927 N N   . VAL   B 1 204 ? 3.122   -25.914 14.184 1.000 10.923 0 204 VAL   B N   1 ? 
ATOM   3928 C CA  . VAL   B 1 204 ? 3.048   -25.066 13.000 1.000 11.084 0 204 VAL   B CA  1 ? 
ATOM   3929 C C   . VAL   B 1 204 ? 1.577   -24.688 12.779 1.000 11.412 0 204 VAL   B C   1 ? 
ATOM   3930 O O   . VAL   B 1 204 ? 1.261   -23.545 12.471 1.000 11.253 0 204 VAL   B O   1 ? 
ATOM   3931 C CB  . VAL   B 1 204 ? 3.680   -25.720 11.749 1.000 10.251 0 204 VAL   B CB  1 ? 
ATOM   3932 C CG1 . VAL   B 1 204 ? 3.537   -24.860 10.506 1.000 10.106 0 204 VAL   B CG1 1 ? 
ATOM   3933 C CG2 . VAL   B 1 204 ? 5.143   -26.077 11.969 1.000 10.399 0 204 VAL   B CG2 1 ? 
ATOM   3934 N N   . LEU   B 1 205 ? 0.680   -25.653 13.004 1.000 11.612 0 205 LEU   B N   1 ? 
ATOM   3935 C CA  . LEU   B 1 205 ? -0.741  -25.440 12.789 1.000 12.162 0 205 LEU   B CA  1 ? 
ATOM   3936 C C   . LEU   B 1 205 ? -1.279  -24.436 13.814 1.000 12.221 0 205 LEU   B C   1 ? 
ATOM   3937 O O   . LEU   B 1 205 ? -2.054  -23.557 13.458 1.000 11.609 0 205 LEU   B O   1 ? 
ATOM   3938 C CB  . LEU   B 1 205 ? -1.449  -26.796 12.825 1.000 11.536 0 205 LEU   B CB  1 ? 
ATOM   3939 C CG  . LEU   B 1 205 ? -1.200  -27.646 11.568 1.000 12.355 0 205 LEU   B CG  1 ? 
ATOM   3940 C CD1 . LEU   B 1 205 ? -1.631  -29.097 11.752 1.000 11.832 0 205 LEU   B CD1 1 ? 
ATOM   3941 C CD2 . LEU   B 1 205 ? -1.904  -27.036 10.368 1.000 13.071 0 205 LEU   B CD2 1 ? 
ATOM   3942 N N   . ALA   B 1 206 ? -0.860  -24.567 15.085 1.000 12.029 0 206 ALA   B N   1 ? 
ATOM   3943 C CA  . ALA   B 1 206 ? -1.287  -23.634 16.113 1.000 11.654 0 206 ALA   B CA  1 ? 
ATOM   3944 C C   . ALA   B 1 206 ? -0.954  -22.218 15.662 1.000 10.959 0 206 ALA   B C   1 ? 
ATOM   3945 O O   . ALA   B 1 206 ? -1.786  -21.322 15.736 1.000 10.333 0 206 ALA   B O   1 ? 
ATOM   3946 C CB  . ALA   B 1 206 ? -0.653  -23.968 17.435 1.000 12.162 0 206 ALA   B CB  1 ? 
ATOM   3947 N N   . TRP   B 1 207 ? 0.252   -22.048 15.113 1.000 11.279 0 207 TRP   B N   1 ? 
ATOM   3948 C CA  . TRP   B 1 207 ? 0.738   -20.738 14.721 1.000 11.491 0 207 TRP   B CA  1 ? 
ATOM   3949 C C   . TRP   B 1 207 ? -0.031  -20.224 13.513 1.000 11.142 0 207 TRP   B C   1 ? 
ATOM   3950 O O   . TRP   B 1 207 ? -0.269  -19.044 13.421 1.000 11.501 0 207 TRP   B O   1 ? 
ATOM   3951 C CB  . TRP   B 1 207 ? 2.239   -20.835 14.470 1.000 12.582 0 207 TRP   B CB  1 ? 
ATOM   3952 C CG  . TRP   B 1 207 ? 2.925   -19.629 13.891 1.000 13.986 0 207 TRP   B CG  1 ? 
ATOM   3953 C CD1 . TRP   B 1 207 ? 3.332   -18.512 14.560 1.000 14.785 0 207 TRP   B CD1 1 ? 
ATOM   3954 C CD2 . TRP   B 1 207 ? 3.361   -19.477 12.528 1.000 14.356 0 207 TRP   B CD2 1 ? 
ATOM   3955 N NE1 . TRP   B 1 207 ? 4.033   -17.705 13.710 1.000 15.890 0 207 TRP   B NE1 1 ? 
ATOM   3956 C CE2 . TRP   B 1 207 ? 4.045   -18.256 12.456 1.000 15.094 0 207 TRP   B CE2 1 ? 
ATOM   3957 C CE3 . TRP   B 1 207 ? 3.230   -20.249 11.365 1.000 16.735 0 207 TRP   B CE3 1 ? 
ATOM   3958 C CZ2 . TRP   B 1 207 ? 4.598   -17.781 11.266 1.000 16.073 0 207 TRP   B CZ2 1 ? 
ATOM   3959 C CZ3 . TRP   B 1 207 ? 3.806   -19.801 10.192 1.000 17.001 0 207 TRP   B CZ3 1 ? 
ATOM   3960 C CH2 . TRP   B 1 207 ? 4.496   -18.587 10.150 1.000 17.181 0 207 TRP   B CH2 1 ? 
ATOM   3961 N N   . LEU   B 1 208 ? -0.364  -21.079 12.541 1.000 11.676 0 208 LEU   B N   1 ? 
ATOM   3962 C CA  . LEU   B 1 208 ? -1.223  -20.646 11.454 1.000 11.532 0 208 LEU   B CA  1 ? 
ATOM   3963 C C   . LEU   B 1 208 ? -2.578  -20.196 12.020 1.000 10.887 0 208 LEU   B C   1 ? 
ATOM   3964 O O   . LEU   B 1 208 ? -3.155  -19.220 11.541 1.000 10.646 0 208 LEU   B O   1 ? 
ATOM   3965 C CB  . LEU   B 1 208 ? -1.372  -21.759 10.406 1.000 12.427 0 208 LEU   B CB  1 ? 
ATOM   3966 C CG  . LEU   B 1 208 ? -0.109  -22.122 9.623  1.000 13.203 0 208 LEU   B CG  1 ? 
ATOM   3967 C CD1 . LEU   B 1 208 ? -0.375  -23.286 8.676  1.000 12.979 0 208 LEU   B CD1 1 ? 
ATOM   3968 C CD2 . LEU   B 1 208 ? 0.432   -20.932 8.827  1.000 13.765 0 208 LEU   B CD2 1 ? 
ATOM   3969 N N   . TYR   B 1 209 ? -3.083  -20.857 13.067 1.000 11.177 0 209 TYR   B N   1 ? 
ATOM   3970 C CA  . TYR   B 1 209 ? -4.288  -20.380 13.739 1.000 11.261 0 209 TYR   B CA  1 ? 
ATOM   3971 C C   . TYR   B 1 209 ? -4.066  -18.984 14.332 1.000 12.549 0 209 TYR   B C   1 ? 
ATOM   3972 O O   . TYR   B 1 209 ? -4.897  -18.084 14.156 1.000 12.880 0 209 TYR   B O   1 ? 
ATOM   3973 C CB  . TYR   B 1 209 ? -4.813  -21.402 14.750 1.000 11.284 0 209 TYR   B CB  1 ? 
ATOM   3974 C CG  . TYR   B 1 209 ? -5.623  -22.519 14.095 1.000 12.619 0 209 TYR   B CG  1 ? 
ATOM   3975 C CD1 . TYR   B 1 209 ? -6.870  -22.292 13.519 1.000 13.082 0 209 TYR   B CD1 1 ? 
ATOM   3976 C CD2 . TYR   B 1 209 ? -5.133  -23.819 14.052 1.000 12.221 0 209 TYR   B CD2 1 ? 
ATOM   3977 C CE1 . TYR   B 1 209 ? -7.587  -23.319 12.916 1.000 13.390 0 209 TYR   B CE1 1 ? 
ATOM   3978 C CE2 . TYR   B 1 209 ? -5.822  -24.844 13.433 1.000 12.729 0 209 TYR   B CE2 1 ? 
ATOM   3979 C CZ  . TYR   B 1 209 ? -7.068  -24.608 12.889 1.000 13.142 0 209 TYR   B CZ  1 ? 
ATOM   3980 O OH  . TYR   B 1 209 ? -7.716  -25.677 12.362 1.000 12.276 0 209 TYR   B OH  1 ? 
ATOM   3981 N N   . ALA   B 1 210 ? -2.936  -18.798 15.023 1.000 12.928 0 210 ALA   B N   1 ? 
ATOM   3982 C CA  . ALA   B 1 210 ? -2.575  -17.505 15.581 1.000 12.857 0 210 ALA   B CA  1 ? 
ATOM   3983 C C   . ALA   B 1 210 ? -2.611  -16.422 14.507 1.000 12.897 0 210 ALA   B C   1 ? 
ATOM   3984 O O   . ALA   B 1 210 ? -3.125  -15.329 14.735 1.000 12.298 0 210 ALA   B O   1 ? 
ATOM   3985 C CB  . ALA   B 1 210 ? -1.202  -17.604 16.245 1.000 13.245 0 210 ALA   B CB  1 ? 
ATOM   3986 N N   . ALA   B 1 211 ? -2.055  -16.729 13.334 1.000 12.721 0 211 ALA   B N   1 ? 
ATOM   3987 C CA  . ALA   B 1 211 ? -2.053  -15.804 12.213 1.000 12.876 0 211 ALA   B CA  1 ? 
ATOM   3988 C C   . ALA   B 1 211 ? -3.479  -15.406 11.808 1.000 13.181 0 211 ALA   B C   1 ? 
ATOM   3989 O O   . ALA   B 1 211 ? -3.761  -14.224 11.611 1.000 12.097 0 211 ALA   B O   1 ? 
ATOM   3990 C CB  . ALA   B 1 211 ? -1.315  -16.439 11.061 1.000 13.343 0 211 ALA   B CB  1 ? 
ATOM   3991 N N   . VAL   B 1 212 ? -4.386  -16.386 11.700 1.000 14.001 0 212 VAL   B N   1 ? 
ATOM   3992 C CA  . VAL   B 1 212 ? -5.752  -16.089 11.309 1.000 15.226 0 212 VAL   B CA  1 ? 
ATOM   3993 C C   . VAL   B 1 212 ? -6.451  -15.209 12.356 1.000 17.023 0 212 VAL   B C   1 ? 
ATOM   3994 O O   . VAL   B 1 212 ? -7.155  -14.258 12.013 1.000 17.478 0 212 VAL   B O   1 ? 
ATOM   3995 C CB  . VAL   B 1 212 ? -6.555  -17.367 11.033 1.000 14.374 0 212 VAL   B CB  1 ? 
ATOM   3996 C CG1 . VAL   B 1 212 ? -8.035  -17.051 10.837 1.000 15.616 0 212 VAL   B CG1 1 ? 
ATOM   3997 C CG2 . VAL   B 1 212 ? -5.977  -18.092 9.838  1.000 14.066 0 212 VAL   B CG2 1 ? 
ATOM   3998 N N   . ILE   B 1 213 ? -6.337  -15.576 13.627 1.000 18.055 0 213 ILE   B N   1 ? 
ATOM   3999 C CA  . ILE   B 1 213 ? -6.911  -14.795 14.715 1.000 17.957 0 213 ILE   B CA  1 ? 
ATOM   4000 C C   . ILE   B 1 213 ? -6.429  -13.349 14.626 1.000 18.260 0 213 ILE   B C   1 ? 
ATOM   4001 O O   . ILE   B 1 213 ? -7.178  -12.454 14.976 1.000 18.955 0 213 ILE   B O   1 ? 
ATOM   4002 C CB  . ILE   B 1 213 ? -6.561  -15.420 16.078 1.000 18.429 0 213 ILE   B CB  1 ? 
ATOM   4003 C CG1 . ILE   B 1 213 ? -7.253  -16.775 16.288 1.000 20.198 0 213 ILE   B CG1 1 ? 
ATOM   4004 C CG2 . ILE   B 1 213 ? -6.879  -14.463 17.214 1.000 18.799 0 213 ILE   B CG2 1 ? 
ATOM   4005 C CD1 . ILE   B 1 213 ? -6.642  -17.601 17.396 1.000 19.098 0 213 ILE   B CD1 1 ? 
ATOM   4006 N N   . ASN   B 1 214 ? -5.198  -13.115 14.150 1.000 19.218 0 214 ASN   B N   1 ? 
ATOM   4007 C CA  . ASN   B 1 214 ? -4.648  -11.772 14.081 1.000 19.790 0 214 ASN   B CA  1 ? 
ATOM   4008 C C   . ASN   B 1 214 ? -4.886  -11.132 12.717 1.000 21.487 0 214 ASN   B C   1 ? 
ATOM   4009 O O   . ASN   B 1 214 ? -4.453  -10.010 12.492 1.000 22.757 0 214 ASN   B O   1 ? 
ATOM   4010 C CB  . ASN   B 1 214 ? -3.175  -11.754 14.473 1.000 22.788 0 214 ASN   B CB  1 ? 
ATOM   4011 C CG  . ASN   B 1 214 ? -3.006  -11.829 15.974 1.000 24.904 0 214 ASN   B CG  1 ? 
ATOM   4012 O OD1 . ASN   B 1 214 ? -3.097  -10.812 16.666 1.000 27.239 0 214 ASN   B OD1 1 ? 
ATOM   4013 N ND2 . ASN   B 1 214 ? -2.802  -13.037 16.480 1.000 22.774 0 214 ASN   B ND2 1 ? 
ATOM   4014 N N   . GLY   B 1 215 ? -5.583  -11.827 11.811 1.000 22.746 0 215 GLY   B N   1 ? 
ATOM   4015 C CA  . GLY   B 1 215 ? -6.059  -11.217 10.585 1.000 21.980 0 215 GLY   B CA  1 ? 
ATOM   4016 C C   . GLY   B 1 215 ? -5.125  -11.425 9.400  1.000 23.175 0 215 GLY   B C   1 ? 
ATOM   4017 O O   . GLY   B 1 215 ? -5.322  -10.822 8.357  1.000 24.493 0 215 GLY   B O   1 ? 
ATOM   4018 N N   . ASP   B 1 216 ? -4.136  -12.312 9.535  1.000 23.660 0 216 ASP   B N   1 ? 
ATOM   4019 C CA  . ASP   B 1 216 ? -3.230  -12.616 8.434  1.000 25.189 0 216 ASP   B CA  1 ? 
ATOM   4020 C C   . ASP   B 1 216 ? -3.741  -13.910 7.803  1.000 25.182 0 216 ASP   B C   1 ? 
ATOM   4021 O O   . ASP   B 1 216 ? -3.446  -14.983 8.325  1.000 25.965 0 216 ASP   B O   1 ? 
ATOM   4022 C CB  . ASP   B 1 216 ? -1.792  -12.679 8.975  1.000 28.577 0 216 ASP   B CB  1 ? 
ATOM   4023 C CG  . ASP   B 1 216 ? -0.671  -12.280 8.027  1.000 33.153 0 216 ASP   B CG  1 ? 
ATOM   4024 O OD1 . ASP   B 1 216 ? -0.935  -12.021 6.831  1.000 37.341 0 216 ASP   B OD1 1 ? 
ATOM   4025 O OD2 . ASP   B 1 216 ? 0.473   -12.230 8.501  1.000 37.658 0 216 ASP   B OD2 1 ? 
ATOM   4026 N N   . ARG   B 1 217 ? -4.530  -13.804 6.714  1.000 25.266 0 217 ARG   B N   1 ? 
ATOM   4027 C CA  . ARG   B 1 217 ? -5.390  -14.888 6.255  1.000 26.591 0 217 ARG   B CA  1 ? 
ATOM   4028 C C   . ARG   B 1 217 ? -5.166  -15.232 4.777  1.000 22.096 0 217 ARG   B C   1 ? 
ATOM   4029 O O   . ARG   B 1 217 ? -5.880  -16.047 4.198  1.000 19.654 0 217 ARG   B O   1 ? 
ATOM   4030 C CB  . ARG   B 1 217 ? -6.857  -14.545 6.571  1.000 29.356 0 217 ARG   B CB  1 ? 
ATOM   4031 C CG  . ARG   B 1 217 ? -7.495  -13.434 5.743  1.000 34.688 0 217 ARG   B CG  1 ? 
ATOM   4032 C CD  . ARG   B 1 217 ? -8.707  -12.831 6.473  1.000 40.914 0 217 ARG   B CD  1 ? 
ATOM   4033 N NE  . ARG   B 1 217 ? -9.207  -11.554 5.955  1.000 41.333 0 217 ARG   B NE  1 ? 
ATOM   4034 C CZ  . ARG   B 1 217 ? -9.869  -11.412 4.807  1.000 52.986 0 217 ARG   B CZ  1 ? 
ATOM   4035 N NH1 . ARG   B 1 217 ? -10.330 -10.227 4.433  1.000 56.956 0 217 ARG   B NH1 1 ? 
ATOM   4036 N NH2 . ARG   B 1 217 ? -10.089 -12.462 4.033  1.000 55.513 0 217 ARG   B NH2 1 ? 
ATOM   4037 N N   . TRP   B 1 218 ? -4.119  -14.686 4.168  1.000 20.769 0 218 TRP   B N   1 ? 
ATOM   4038 C CA  . TRP   B 1 218 ? -3.944  -14.808 2.734  1.000 17.094 0 218 TRP   B CA  1 ? 
ATOM   4039 C C   . TRP   B 1 218 ? -3.711  -16.266 2.337  1.000 16.420 0 218 TRP   B C   1 ? 
ATOM   4040 O O   . TRP   B 1 218 ? -3.907  -16.623 1.185  1.000 14.772 0 218 TRP   B O   1 ? 
ATOM   4041 C CB  . TRP   B 1 218 ? -2.796  -13.894 2.296  1.000 17.360 0 218 TRP   B CB  1 ? 
ATOM   4042 C CG  . TRP   B 1 218 ? -1.455  -14.292 2.863  1.000 16.475 0 218 TRP   B CG  1 ? 
ATOM   4043 C CD1 . TRP   B 1 218 ? -0.800  -13.757 3.940  1.000 15.434 0 218 TRP   B CD1 1 ? 
ATOM   4044 C CD2 . TRP   B 1 218 ? -0.600  -15.326 2.342  1.000 16.033 0 218 TRP   B CD2 1 ? 
ATOM   4045 N NE1 . TRP   B 1 218 ? 0.403   -14.387 4.120  1.000 16.108 0 218 TRP   B NE1 1 ? 
ATOM   4046 C CE2 . TRP   B 1 218 ? 0.542   -15.365 3.170  1.000 17.232 0 218 TRP   B CE2 1 ? 
ATOM   4047 C CE3 . TRP   B 1 218 ? -0.695  -16.220 1.271  1.000 16.735 0 218 TRP   B CE3 1 ? 
ATOM   4048 C CZ2 . TRP   B 1 218 ? 1.583   -16.257 2.940  1.000 17.801 0 218 TRP   B CZ2 1 ? 
ATOM   4049 C CZ3 . TRP   B 1 218 ? 0.323   -17.118 1.064  1.000 17.297 0 218 TRP   B CZ3 1 ? 
ATOM   4050 C CH2 . TRP   B 1 218 ? 1.444   -17.134 1.889  1.000 17.636 0 218 TRP   B CH2 1 ? 
ATOM   4051 N N   . PHE   B 1 219 ? -3.220  -17.103 3.262  1.000 15.860 0 219 PHE   B N   1 ? 
ATOM   4052 C CA  . PHE   B 1 219 ? -2.800  -18.462 2.916  1.000 15.447 0 219 PHE   B CA  1 ? 
ATOM   4053 C C   . PHE   B 1 219 ? -3.944  -19.465 3.083  1.000 14.731 0 219 PHE   B C   1 ? 
ATOM   4054 O O   . PHE   B 1 219 ? -3.748  -20.642 2.870  1.000 14.502 0 219 PHE   B O   1 ? 
ATOM   4055 C CB  . PHE   B 1 219 ? -1.603  -18.884 3.784  1.000 16.241 0 219 PHE   B CB  1 ? 
ATOM   4056 C CG  . PHE   B 1 219 ? -1.902  -18.807 5.258  1.000 14.658 0 219 PHE   B CG  1 ? 
ATOM   4057 C CD1 . PHE   B 1 219 ? -2.562  -19.839 5.904  1.000 14.491 0 219 PHE   B CD1 1 ? 
ATOM   4058 C CD2 . PHE   B 1 219 ? -1.600  -17.663 5.980  1.000 14.080 0 219 PHE   B CD2 1 ? 
ATOM   4059 C CE1 . PHE   B 1 219 ? -2.910  -19.733 7.243  1.000 14.163 0 219 PHE   B CE1 1 ? 
ATOM   4060 C CE2 . PHE   B 1 219 ? -1.969  -17.550 7.313  1.000 13.829 0 219 PHE   B CE2 1 ? 
ATOM   4061 C CZ  . PHE   B 1 219 ? -2.628  -18.575 7.941  1.000 13.815 0 219 PHE   B CZ  1 ? 
ATOM   4062 N N   . LEU   B 1 220 ? -5.114  -19.037 3.560  1.000 16.675 0 220 LEU   B N   1 ? 
ATOM   4063 C CA  . LEU   B 1 220 ? -6.295  -19.887 3.654  1.000 17.018 0 220 LEU   B CA  1 ? 
ATOM   4064 C C   . LEU   B 1 220 ? -6.781  -20.253 2.261  1.000 18.675 0 220 LEU   B C   1 ? 
ATOM   4065 O O   . LEU   B 1 220 ? -6.664  -19.449 1.350  1.000 18.906 0 220 LEU   B O   1 ? 
ATOM   4066 C CB  . LEU   B 1 220 ? -7.395  -19.138 4.411  1.000 17.556 0 220 LEU   B CB  1 ? 
ATOM   4067 C CG  . LEU   B 1 220 ? -7.102  -18.919 5.895  1.000 18.763 0 220 LEU   B CG  1 ? 
ATOM   4068 C CD1 . LEU   B 1 220 ? -8.202  -18.105 6.564  1.000 20.100 0 220 LEU   B CD1 1 ? 
ATOM   4069 C CD2 . LEU   B 1 220 ? -6.911  -20.261 6.586  1.000 17.861 0 220 LEU   B CD2 1 ? 
ATOM   4070 N N   . ASN   B 1 221 ? -7.285  -21.477 2.092  1.000 20.100 0 221 ASN   B N   1 ? 
ATOM   4071 C CA  . ASN   B 1 221 ? -7.801  -21.885 0.795  1.000 20.735 0 221 ASN   B CA  1 ? 
ATOM   4072 C C   . ASN   B 1 221 ? -9.067  -22.699 1.006  1.000 19.504 0 221 ASN   B C   1 ? 
ATOM   4073 O O   . ASN   B 1 221 ? -9.393  -23.091 2.122  1.000 17.150 0 221 ASN   B O   1 ? 
ATOM   4074 C CB  . ASN   B 1 221 ? -6.772  -22.644 -0.055 1.000 20.222 0 221 ASN   B CB  1 ? 
ATOM   4075 C CG  . ASN   B 1 221 ? -6.258  -23.890 0.631  1.000 19.481 0 221 ASN   B CG  1 ? 
ATOM   4076 O OD1 . ASN   B 1 221 ? -7.039  -24.654 1.198  1.000 18.055 0 221 ASN   B OD1 1 ? 
ATOM   4077 N ND2 . ASN   B 1 221 ? -4.948  -24.099 0.584  1.000 20.144 0 221 ASN   B ND2 1 ? 
ATOM   4078 N N   . ARG   B 1 222 ? -9.792  -22.915 -0.088 1.000 20.905 0 222 ARG   B N   1 ? 
ATOM   4079 C CA  . ARG   B 1 222 ? -11.093 -23.571 -0.024 1.000 23.473 0 222 ARG   B CA  1 ? 
ATOM   4080 C C   . ARG   B 1 222 ? -10.938 -25.093 0.023  1.000 21.195 0 222 ARG   B C   1 ? 
ATOM   4081 O O   . ARG   B 1 222 ? -11.945 -25.808 -0.036 1.000 18.691 0 222 ARG   B O   1 ? 
ATOM   4082 C CB  . ARG   B 1 222 ? -11.951 -23.183 -1.236 1.000 27.264 0 222 ARG   B CB  1 ? 
ATOM   4083 C CG  . ARG   B 1 222 ? -11.767 -24.082 -2.455 1.000 33.946 0 222 ARG   B CG  1 ? 
ATOM   4084 C CD  . ARG   B 1 222 ? -12.505 -23.627 -3.706 1.000 40.342 0 222 ARG   B CD  1 ? 
ATOM   4085 N NE  . ARG   B 1 222 ? -11.704 -22.610 -4.368 1.000 46.689 0 222 ARG   B NE  1 ? 
ATOM   4086 C CZ  . ARG   B 1 222 ? -11.009 -22.776 -5.493 1.000 52.216 0 222 ARG   B CZ  1 ? 
ATOM   4087 N NH1 . ARG   B 1 222 ? -10.027 -21.935 -5.786 1.000 50.671 0 222 ARG   B NH1 1 ? 
ATOM   4088 N NH2 . ARG   B 1 222 ? -11.235 -23.822 -6.272 1.000 48.632 0 222 ARG   B NH2 1 ? 
ATOM   4089 N N   . PHE   B 1 223 ? -9.697  -25.584 0.117  1.000 18.119 0 223 PHE   B N   1 ? 
ATOM   4090 C CA  . PHE   B 1 223 ? -9.451  -27.004 -0.077 1.000 18.611 0 223 PHE   B CA  1 ? 
ATOM   4091 C C   . PHE   B 1 223 ? -9.306  -27.673 1.277  1.000 19.439 0 223 PHE   B C   1 ? 
ATOM   4092 O O   . PHE   B 1 223 ? -9.110  -27.036 2.296  1.000 19.447 0 223 PHE   B O   1 ? 
ATOM   4093 C CB  . PHE   B 1 223 ? -8.235  -27.278 -0.978 1.000 17.861 0 223 PHE   B CB  1 ? 
ATOM   4094 C CG  . PHE   B 1 223 ? -8.270  -26.515 -2.280 1.000 17.423 0 223 PHE   B CG  1 ? 
ATOM   4095 C CD1 . PHE   B 1 223 ? -9.210  -26.819 -3.255 1.000 18.682 0 223 PHE   B CD1 1 ? 
ATOM   4096 C CD2 . PHE   B 1 223 ? -7.429  -25.434 -2.490 1.000 17.487 0 223 PHE   B CD2 1 ? 
ATOM   4097 C CE1 . PHE   B 1 223 ? -9.278  -26.077 -4.431 1.000 18.782 0 223 PHE   B CE1 1 ? 
ATOM   4098 C CE2 . PHE   B 1 223 ? -7.485  -24.690 -3.663 1.000 17.287 0 223 PHE   B CE2 1 ? 
ATOM   4099 C CZ  . PHE   B 1 223 ? -8.420  -25.007 -4.626 1.000 18.900 0 223 PHE   B CZ  1 ? 
ATOM   4100 N N   . THR   B 1 224 ? -9.369  -28.998 1.224  1.000 19.643 0 224 THR   B N   1 ? 
ATOM   4101 C CA  . THR   B 1 224 ? -9.404  -29.828 2.393  1.000 19.223 0 224 THR   B CA  1 ? 
ATOM   4102 C C   . THR   B 1 224 ? -8.513  -31.033 2.081  1.000 18.905 0 224 THR   B C   1 ? 
ATOM   4103 O O   . THR   B 1 224 ? -8.325  -31.388 0.926  1.000 18.846 0 224 THR   B O   1 ? 
ATOM   4104 C CB  . THR   B 1 224 ? -10.899 -30.080 2.598  1.000 21.756 0 224 THR   B CB  1 ? 
ATOM   4105 O OG1 . THR   B 1 224 ? -11.374 -29.510 3.814  1.000 21.498 0 224 THR   B OG1 1 ? 
ATOM   4106 C CG2 . THR   B 1 224 ? -11.254 -31.531 2.434  1.000 23.497 0 224 THR   B CG2 1 ? 
ATOM   4107 N N   . THR   B 1 225 ? -7.933  -31.669 3.086  1.000 17.696 0 225 THR   B N   1 ? 
ATOM   4108 C CA  . THR   B 1 225 ? -7.168  -32.878 2.841  1.000 18.285 0 225 THR   B CA  1 ? 
ATOM   4109 C C   . THR   B 1 225 ? -7.608  -33.895 3.887  1.000 19.579 0 225 THR   B C   1 ? 
ATOM   4110 O O   . THR   B 1 225 ? -8.137  -33.519 4.933  1.000 19.637 0 225 THR   B O   1 ? 
ATOM   4111 C CB  . THR   B 1 225 ? -5.653  -32.608 2.913  1.000 17.628 0 225 THR   B CB  1 ? 
ATOM   4112 O OG1 . THR   B 1 225 ? -4.907  -33.813 2.820  1.000 18.518 0 225 THR   B OG1 1 ? 
ATOM   4113 C CG2 . THR   B 1 225 ? -5.208  -32.015 4.227  1.000 17.256 0 225 THR   B CG2 1 ? 
ATOM   4114 N N   . THR   B 1 226 ? -7.359  -35.177 3.617  1.000 19.458 0 226 THR   B N   1 ? 
ATOM   4115 C CA  . THR   B 1 226 ? -7.505  -36.205 4.630  1.000 19.177 0 226 THR   B CA  1 ? 
ATOM   4116 C C   . THR   B 1 226 ? -6.256  -36.196 5.509  1.000 18.678 0 226 THR   B C   1 ? 
ATOM   4117 O O   . THR   B 1 226 ? -5.204  -35.718 5.097  1.000 16.316 0 226 THR   B O   1 ? 
ATOM   4118 C CB  . THR   B 1 226 ? -7.689  -37.592 3.998  1.000 20.172 0 226 THR   B CB  1 ? 
ATOM   4119 O OG1 . THR   B 1 226 ? -6.456  -37.942 3.365  1.000 18.146 0 226 THR   B OG1 1 ? 
ATOM   4120 C CG2 . THR   B 1 226 ? -8.842  -37.658 3.017  1.000 19.814 0 226 THR   B CG2 1 ? 
ATOM   4121 N N   . LEU   B 1 227 ? -6.356  -36.801 6.691  1.000 19.493 0 227 LEU   B N   1 ? 
ATOM   4122 C CA  . LEU   B 1 227 ? -5.227  -36.832 7.605  1.000 20.980 0 227 LEU   B CA  1 ? 
ATOM   4123 C C   . LEU   B 1 227 ? -4.075  -37.642 7.016  1.000 23.007 0 227 LEU   B C   1 ? 
ATOM   4124 O O   . LEU   B 1 227 ? -2.905  -37.271 7.162  1.000 18.432 0 227 LEU   B O   1 ? 
ATOM   4125 C CB  . LEU   B 1 227 ? -5.675  -37.413 8.945  1.000 22.151 0 227 LEU   B CB  1 ? 
ATOM   4126 C CG  . LEU   B 1 227 ? -4.625  -37.367 10.061 1.000 22.948 0 227 LEU   B CG  1 ? 
ATOM   4127 C CD1 . LEU   B 1 227 ? -4.115  -35.955 10.291 1.000 23.248 0 227 LEU   B CD1 1 ? 
ATOM   4128 C CD2 . LEU   B 1 227 ? -5.218  -37.915 11.343 1.000 25.161 0 227 LEU   B CD2 1 ? 
ATOM   4129 N N   . ASN   B 1 228 ? -4.406  -38.787 6.394  1.000 24.235 0 228 ASN   B N   1 ? 
ATOM   4130 C CA  . ASN   B 1 228 ? -3.372  -39.642 5.841  1.000 24.970 0 228 ASN   B CA  1 ? 
ATOM   4131 C C   . ASN   B 1 228 ? -2.681  -38.919 4.694  1.000 23.020 0 228 ASN   B C   1 ? 
ATOM   4132 O O   . ASN   B 1 228 ? -1.464  -38.913 4.656  1.000 22.566 0 228 ASN   B O   1 ? 
ATOM   4133 C CB  . ASN   B 1 228 ? -3.894  -41.024 5.430  1.000 29.532 0 228 ASN   B CB  1 ? 
ATOM   4134 C CG  . ASN   B 1 228 ? -4.058  -41.952 6.614  1.000 39.549 0 228 ASN   B CG  1 ? 
ATOM   4135 O OD1 . ASN   B 1 228 ? -3.829  -41.563 7.760  1.000 39.996 0 228 ASN   B OD1 1 ? 
ATOM   4136 N ND2 . ASN   B 1 228 ? -4.489  -43.179 6.358  1.000 49.859 0 228 ASN   B ND2 1 ? 
ATOM   4137 N N   . ASP   B 1 229 ? -3.453  -38.302 3.786  1.000 20.935 0 229 ASP   B N   1 ? 
ATOM   4138 C CA  . ASP   B 1 229 ? -2.886  -37.581 2.658  1.000 20.819 0 229 ASP   B CA  1 ? 
ATOM   4139 C C   . ASP   B 1 229 ? -2.021  -36.403 3.118  1.000 19.977 0 229 ASP   B C   1 ? 
ATOM   4140 O O   . ASP   B 1 229 ? -1.013  -36.081 2.484  1.000 19.324 0 229 ASP   B O   1 ? 
ATOM   4141 C CB  . ASP   B 1 229 ? -3.993  -37.143 1.692  1.000 23.792 0 229 ASP   B CB  1 ? 
ATOM   4142 C CG  . ASP   B 1 229 ? -4.582  -38.280 0.862  1.000 28.791 0 229 ASP   B CG  1 ? 
ATOM   4143 O OD1 . ASP   B 1 229 ? -3.992  -39.401 0.873  1.000 33.128 0 229 ASP   B OD1 1 ? 
ATOM   4144 O OD2 . ASP   B 1 229 ? -5.630  -38.055 0.203  1.000 32.125 0 229 ASP   B OD2 1 ? 
ATOM   4145 N N   . PHE   B 1 230 ? -2.429  -35.707 4.192  1.000 18.199 0 230 PHE   B N   1 ? 
ATOM   4146 C CA  . PHE   B 1 230 ? -1.592  -34.651 4.751  1.000 16.192 0 230 PHE   B CA  1 ? 
ATOM   4147 C C   . PHE   B 1 230 ? -0.232  -35.205 5.190  1.000 15.580 0 230 PHE   B C   1 ? 
ATOM   4148 O O   . PHE   B 1 230 ? 0.798   -34.661 4.806  1.000 13.369 0 230 PHE   B O   1 ? 
ATOM   4149 C CB  . PHE   B 1 230 ? -2.292  -33.977 5.922  1.000 15.659 0 230 PHE   B CB  1 ? 
ATOM   4150 C CG  . PHE   B 1 230 ? -1.390  -33.019 6.631  1.000 14.630 0 230 PHE   B CG  1 ? 
ATOM   4151 C CD1 . PHE   B 1 230 ? -1.128  -31.774 6.096  1.000 15.006 0 230 PHE   B CD1 1 ? 
ATOM   4152 C CD2 . PHE   B 1 230 ? -0.748  -33.402 7.781  1.000 14.599 0 230 PHE   B CD2 1 ? 
ATOM   4153 C CE1 . PHE   B 1 230 ? -0.232  -30.925 6.724  1.000 16.123 0 230 PHE   B CE1 1 ? 
ATOM   4154 C CE2 . PHE   B 1 230 ? 0.120   -32.546 8.426  1.000 16.475 0 230 PHE   B CE2 1 ? 
ATOM   4155 C CZ  . PHE   B 1 230 ? 0.376   -31.299 7.900  1.000 16.631 0 230 PHE   B CZ  1 ? 
ATOM   4156 N N   . ASN   B 1 231 ? -0.253  -36.292 5.978  1.000 15.454 0 231 ASN   B N   1 ? 
ATOM   4157 C CA  . ASN   B 1 231 ? 0.944   -36.932 6.506  1.000 17.884 0 231 ASN   B CA  1 ? 
ATOM   4158 C C   . ASN   B 1 231 ? 1.847   -37.487 5.399  1.000 18.011 0 231 ASN   B C   1 ? 
ATOM   4159 O O   . ASN   B 1 231 ? 3.061   -37.414 5.504  1.000 16.521 0 231 ASN   B O   1 ? 
ATOM   4160 C CB  . ASN   B 1 231 ? 0.592   -38.028 7.522  1.000 18.649 0 231 ASN   B CB  1 ? 
ATOM   4161 C CG  . ASN   B 1 231 ? 0.208   -37.440 8.864  1.000 20.084 0 231 ASN   B CG  1 ? 
ATOM   4162 O OD1 . ASN   B 1 231 ? 0.757   -36.413 9.270  1.000 22.995 0 231 ASN   B OD1 1 ? 
ATOM   4163 N ND2 . ASN   B 1 231 ? -0.742  -38.046 9.552  1.000 18.711 0 231 ASN   B ND2 1 ? 
ATOM   4164 N N   . LEU   B 1 232 ? 1.261   -38.032 4.333  1.000 18.875 0 232 LEU   B N   1 ? 
ATOM   4165 C CA  . LEU   B 1 232 ? 2.039   -38.511 3.201  1.000 21.814 0 232 LEU   B CA  1 ? 
ATOM   4166 C C   . LEU   B 1 232 ? 2.932   -37.384 2.656  1.000 21.432 0 232 LEU   B C   1 ? 
ATOM   4167 O O   . LEU   B 1 232 ? 4.067   -37.627 2.265  1.000 22.255 0 232 LEU   B O   1 ? 
ATOM   4168 C CB  . LEU   B 1 232 ? 1.071   -39.055 2.135  1.000 23.339 0 232 LEU   B CB  1 ? 
ATOM   4169 C CG  . LEU   B 1 232 ? 0.758   -40.557 2.165  1.000 25.979 0 232 LEU   B CG  1 ? 
ATOM   4170 C CD1 . LEU   B 1 232 ? 0.593   -41.100 3.561  1.000 28.534 0 232 LEU   B CD1 1 ? 
ATOM   4171 C CD2 . LEU   B 1 232 ? -0.509  -40.864 1.369  1.000 26.652 0 232 LEU   B CD2 1 ? 
ATOM   4172 N N   . VAL   B 1 233 ? 2.428   -36.146 2.632  1.000 20.185 0 233 VAL   B N   1 ? 
ATOM   4173 C CA  . VAL   B 1 233 ? 3.157   -35.023 2.066  1.000 19.838 0 233 VAL   B CA  1 ? 
ATOM   4174 C C   . VAL   B 1 233 ? 4.129   -34.454 3.091  1.000 19.571 0 233 VAL   B C   1 ? 
ATOM   4175 O O   . VAL   B 1 233 ? 5.309   -34.274 2.792  1.000 19.351 0 233 VAL   B O   1 ? 
ATOM   4176 C CB  . VAL   B 1 233 ? 2.203   -33.943 1.540  1.000 21.238 0 233 VAL   B CB  1 ? 
ATOM   4177 C CG1 . VAL   B 1 233 ? 2.923   -32.632 1.246  1.000 21.098 0 233 VAL   B CG1 1 ? 
ATOM   4178 C CG2 . VAL   B 1 233 ? 1.463   -34.466 0.313  1.000 22.805 0 233 VAL   B CG2 1 ? 
ATOM   4179 N N   . ALA   B 1 234 ? 3.643   -34.187 4.298  1.000 18.155 0 234 ALA   B N   1 ? 
ATOM   4180 C CA  . ALA   B 1 234 ? 4.434   -33.433 5.253  1.000 18.856 0 234 ALA   B CA  1 ? 
ATOM   4181 C C   . ALA   B 1 234 ? 5.630   -34.239 5.752  1.000 19.358 0 234 ALA   B C   1 ? 
ATOM   4182 O O   . ALA   B 1 234 ? 6.669   -33.663 6.067  1.000 17.563 0 234 ALA   B O   1 ? 
ATOM   4183 C CB  . ALA   B 1 234 ? 3.583   -33.011 6.416  1.000 18.214 0 234 ALA   B CB  1 ? 
ATOM   4184 N N   . MET   B 1 235 ? 5.443   -35.552 5.918  1.000 18.925 0 235 MET   B N   1 ? 
ATOM   4185 C CA  . MET   B 1 235 ? 6.525   -36.415 6.352  1.000 22.013 0 235 MET   B CA  1 ? 
ATOM   4186 C C   . MET   B 1 235 ? 7.706   -36.392 5.363  1.000 20.643 0 235 MET   B C   1 ? 
ATOM   4187 O O   . MET   B 1 235 ? 8.851   -36.526 5.763  1.000 20.006 0 235 MET   B O   1 ? 
ATOM   4188 C CB  . MET   B 1 235 ? 5.984   -37.830 6.550  1.000 25.327 0 235 MET   B CB  1 ? 
ATOM   4189 C CG  . MET   B 1 235 ? 5.130   -37.893 7.825  1.000 29.081 0 235 MET   B CG  1 ? 
ATOM   4190 S SD  . MET   B 1 235 ? 4.410   -39.511 8.110  1.000 36.273 0 235 MET   B SD  1 ? 
ATOM   4191 C CE  . MET   B 1 235 ? 5.856   -40.449 8.618  1.000 33.342 0 235 MET   B CE  1 ? 
ATOM   4192 N N   . LYS   B 1 236 ? 7.456   -36.116 4.087  1.000 19.374 0 236 LYS   B N   1 ? 
ATOM   4193 C CA  . LYS   B 1 236 ? 8.548   -35.977 3.139  1.000 21.088 0 236 LYS   B CA  1 ? 
ATOM   4194 C C   . LYS   B 1 236 ? 9.397   -34.757 3.471  1.000 20.067 0 236 LYS   B C   1 ? 
ATOM   4195 O O   . LYS   B 1 236 ? 10.569  -34.703 3.095  1.000 17.118 0 236 LYS   B O   1 ? 
ATOM   4196 C CB  . LYS   B 1 236 ? 8.008   -35.884 1.713  1.000 23.673 0 236 LYS   B CB  1 ? 
ATOM   4197 C CG  . LYS   B 1 236 ? 7.150   -37.075 1.295  1.000 28.545 0 236 LYS   B CG  1 ? 
ATOM   4198 C CD  . LYS   B 1 236 ? 6.784   -37.090 -0.179 1.000 35.353 0 236 LYS   B CD  1 ? 
ATOM   4199 C CE  . LYS   B 1 236 ? 6.233   -35.768 -0.668 1.000 40.785 0 236 LYS   B CE  1 ? 
ATOM   4200 N NZ  . LYS   B 1 236 ? 5.373   -35.946 -1.865 1.000 48.750 0 236 LYS   B NZ  1 ? 
ATOM   4201 N N   . TYR   B 1 237 ? 8.797   -33.752 4.129  1.000 18.137 0 237 TYR   B N   1 ? 
ATOM   4202 C CA  . TYR   B 1 237 ? 9.527   -32.557 4.490  1.000 18.401 0 237 TYR   B CA  1 ? 
ATOM   4203 C C   . TYR   B 1 237 ? 10.051  -32.660 5.920  1.000 18.802 0 237 TYR   B C   1 ? 
ATOM   4204 O O   . TYR   B 1 237 ? 10.355  -31.644 6.526  1.000 18.461 0 237 TYR   B O   1 ? 
ATOM   4205 C CB  . TYR   B 1 237 ? 8.612   -31.341 4.324  1.000 18.699 0 237 TYR   B CB  1 ? 
ATOM   4206 C CG  . TYR   B 1 237 ? 8.222   -31.052 2.891  1.000 19.788 0 237 TYR   B CG  1 ? 
ATOM   4207 C CD1 . TYR   B 1 237 ? 7.200   -31.753 2.279  1.000 20.564 0 237 TYR   B CD1 1 ? 
ATOM   4208 C CD2 . TYR   B 1 237 ? 8.882   -30.074 2.153  1.000 21.085 0 237 TYR   B CD2 1 ? 
ATOM   4209 C CE1 . TYR   B 1 237 ? 6.815   -31.475 0.974  1.000 21.749 0 237 TYR   B CE1 1 ? 
ATOM   4210 C CE2 . TYR   B 1 237 ? 8.524   -29.806 0.841  1.000 22.943 0 237 TYR   B CE2 1 ? 
ATOM   4211 C CZ  . TYR   B 1 237 ? 7.484   -30.508 0.252  1.000 22.992 0 237 TYR   B CZ  1 ? 
ATOM   4212 O OH  . TYR   B 1 237 ? 7.115   -30.257 -1.032 1.000 25.325 0 237 TYR   B OH  1 ? 
ATOM   4213 N N   . ASN   B 1 238 ? 10.121  -33.878 6.461  1.000 21.173 0 238 ASN   B N   1 ? 
ATOM   4214 C CA  . ASN   B 1 238 ? 10.644  -34.111 7.799  1.000 22.944 0 238 ASN   B CA  1 ? 
ATOM   4215 C C   . ASN   B 1 238 ? 9.787   -33.433 8.889  1.000 22.259 0 238 ASN   B C   1 ? 
ATOM   4216 O O   . ASN   B 1 238 ? 10.289  -32.979 9.911  1.000 23.252 0 238 ASN   B O   1 ? 
ATOM   4217 C CB  . ASN   B 1 238 ? 12.119  -33.712 7.810  1.000 25.827 0 238 ASN   B CB  1 ? 
ATOM   4218 C CG  . ASN   B 1 238 ? 12.853  -34.351 8.960  1.000 31.874 0 238 ASN   B CG  1 ? 
ATOM   4219 O OD1 . ASN   B 1 238 ? 13.589  -33.672 9.673  1.000 37.691 0 238 ASN   B OD1 1 ? 
ATOM   4220 N ND2 . ASN   B 1 238 ? 12.637  -35.642 9.154  1.000 30.643 0 238 ASN   B ND2 1 ? 
ATOM   4221 N N   . TYR   B 1 239 ? 8.472   -33.356 8.670  1.000 19.880 0 239 TYR   B N   1 ? 
ATOM   4222 C CA  . TYR   B 1 239 ? 7.524   -32.993 9.706  1.000 19.415 0 239 TYR   B CA  1 ? 
ATOM   4223 C C   . TYR   B 1 239 ? 7.088   -34.234 10.477 1.000 19.996 0 239 TYR   B C   1 ? 
ATOM   4224 O O   . TYR   B 1 239 ? 6.950   -35.308 9.914  1.000 18.904 0 239 TYR   B O   1 ? 
ATOM   4225 C CB  . TYR   B 1 239 ? 6.311   -32.324 9.059  1.000 17.981 0 239 TYR   B CB  1 ? 
ATOM   4226 C CG  . TYR   B 1 239 ? 6.488   -30.833 8.795  1.000 16.819 0 239 TYR   B CG  1 ? 
ATOM   4227 C CD1 . TYR   B 1 239 ? 7.615   -30.300 8.166  1.000 16.469 0 239 TYR   B CD1 1 ? 
ATOM   4228 C CD2 . TYR   B 1 239 ? 5.482   -29.950 9.165  1.000 17.421 0 239 TYR   B CD2 1 ? 
ATOM   4229 C CE1 . TYR   B 1 239 ? 7.738   -28.932 7.956  1.000 17.415 0 239 TYR   B CE1 1 ? 
ATOM   4230 C CE2 . TYR   B 1 239 ? 5.608   -28.582 8.984  1.000 17.084 0 239 TYR   B CE2 1 ? 
ATOM   4231 C CZ  . TYR   B 1 239 ? 6.727   -28.069 8.366  1.000 16.200 0 239 TYR   B CZ  1 ? 
ATOM   4232 O OH  . TYR   B 1 239 ? 6.708   -26.709 8.222  1.000 18.294 0 239 TYR   B OH  1 ? 
ATOM   4233 N N   . GLU   B 1 240 ? 6.862   -34.069 11.777 1.000 21.650 0 240 GLU   B N   1 ? 
ATOM   4234 C CA  . GLU   B 1 240 ? 6.259   -35.108 12.589 1.000 24.327 0 240 GLU   B CA  1 ? 
ATOM   4235 C C   . GLU   B 1 240 ? 4.894   -35.471 12.017 1.000 22.050 0 240 GLU   B C   1 ? 
ATOM   4236 O O   . GLU   B 1 240 ? 4.146   -34.606 11.578 1.000 19.189 0 240 GLU   B O   1 ? 
ATOM   4237 C CB  . GLU   B 1 240 ? 6.101   -34.639 14.041 1.000 28.374 0 240 GLU   B CB  1 ? 
ATOM   4238 C CG  . GLU   B 1 240 ? 7.424   -34.570 14.802 1.000 36.929 0 240 GLU   B CG  1 ? 
ATOM   4239 C CD  . GLU   B 1 240 ? 8.029   -35.924 15.163 1.000 43.278 0 240 GLU   B CD  1 ? 
ATOM   4240 O OE1 . GLU   B 1 240 ? 7.280   -36.761 15.706 1.000 49.990 0 240 GLU   B OE1 1 ? 
ATOM   4241 O OE2 . GLU   B 1 240 ? 9.243   -36.153 14.904 1.000 44.946 0 240 GLU   B OE2 1 ? 
ATOM   4242 N N   . PRO   B 1 241 ? 4.487   -36.755 12.052 1.000 22.314 0 241 PRO   B N   1 ? 
ATOM   4243 C CA  . PRO   B 1 241 ? 3.131   -37.105 11.653 1.000 23.281 0 241 PRO   B CA  1 ? 
ATOM   4244 C C   . PRO   B 1 241 ? 2.140   -36.390 12.563 1.000 21.935 0 241 PRO   B C   1 ? 
ATOM   4245 O O   . PRO   B 1 241 ? 2.381   -36.220 13.748 1.000 19.823 0 241 PRO   B O   1 ? 
ATOM   4246 C CB  . PRO   B 1 241 ? 3.025   -38.638 11.794 1.000 24.220 0 241 PRO   B CB  1 ? 
ATOM   4247 C CG  . PRO   B 1 241 ? 4.293   -39.078 12.526 1.000 24.172 0 241 PRO   B CG  1 ? 
ATOM   4248 C CD  . PRO   B 1 241 ? 5.274   -37.915 12.495 1.000 24.034 0 241 PRO   B CD  1 ? 
ATOM   4249 N N   . LEU   B 1 242 ? 1.026   -35.962 11.981 1.000 20.823 0 242 LEU   B N   1 ? 
ATOM   4250 C CA  . LEU   B 1 242 ? -0.067  -35.435 12.767 1.000 21.129 0 242 LEU   B CA  1 ? 
ATOM   4251 C C   . LEU   B 1 242 ? -1.008  -36.591 13.123 1.000 21.125 0 242 LEU   B C   1 ? 
ATOM   4252 O O   . LEU   B 1 242 ? -1.513  -37.294 12.239 1.000 22.550 0 242 LEU   B O   1 ? 
ATOM   4253 C CB  . LEU   B 1 242 ? -0.745  -34.333 11.940 1.000 20.062 0 242 LEU   B CB  1 ? 
ATOM   4254 C CG  . LEU   B 1 242 ? -1.685  -33.405 12.705 1.000 19.640 0 242 LEU   B CG  1 ? 
ATOM   4255 C CD1 . LEU   B 1 242 ? -0.885  -32.399 13.552 1.000 19.735 0 242 LEU   B CD1 1 ? 
ATOM   4256 C CD2 . LEU   B 1 242 ? -2.623  -32.705 11.728 1.000 21.008 0 242 LEU   B CD2 1 ? 
ATOM   4257 N N   . THR   B 1 243 ? -1.240  -36.772 14.425 1.000 20.537 0 243 THR   B N   1 ? 
ATOM   4258 C CA  . THR   B 1 243 ? -2.112  -37.812 14.953 1.000 21.308 0 243 THR   B CA  1 ? 
ATOM   4259 C C   . THR   B 1 243 ? -3.496  -37.240 15.263 1.000 22.126 0 243 THR   B C   1 ? 
ATOM   4260 O O   . THR   B 1 243 ? -3.696  -36.013 15.330 1.000 20.708 0 243 THR   B O   1 ? 
ATOM   4261 C CB  . THR   B 1 243 ? -1.569  -38.388 16.269 1.000 22.243 0 243 THR   B CB  1 ? 
ATOM   4262 O OG1 . THR   B 1 243 ? -1.659  -37.367 17.263 1.000 22.681 0 243 THR   B OG1 1 ? 
ATOM   4263 C CG2 . THR   B 1 243 ? -0.138  -38.874 16.153 1.000 23.831 0 243 THR   B CG2 1 ? 
ATOM   4264 N N   . GLN   B 1 244 ? -4.444  -38.149 15.504 1.000 21.902 0 244 GLN   B N   1 ? 
ATOM   4265 C CA  . GLN   B 1 244 ? -5.779  -37.748 15.899 1.000 22.711 0 244 GLN   B CA  1 ? 
ATOM   4266 C C   . GLN   B 1 244 ? -5.735  -36.992 17.225 1.000 22.412 0 244 GLN   B C   1 ? 
ATOM   4267 O O   . GLN   B 1 244 ? -6.518  -36.067 17.409 1.000 25.758 0 244 GLN   B O   1 ? 
ATOM   4268 C CB  . GLN   B 1 244 ? -6.702  -38.962 15.956 1.000 25.227 0 244 GLN   B CB  1 ? 
ATOM   4269 C CG  . GLN   B 1 244 ? -8.145  -38.606 16.259 1.000 26.779 0 244 GLN   B CG  1 ? 
ATOM   4270 C CD  . GLN   B 1 244 ? -8.741  -37.720 15.196 1.000 30.392 0 244 GLN   B CD  1 ? 
ATOM   4271 O OE1 . GLN   B 1 244 ? -8.669  -38.017 14.011 1.000 34.175 0 244 GLN   B OE1 1 ? 
ATOM   4272 N NE2 . GLN   B 1 244 ? -9.316  -36.600 15.608 1.000 33.944 0 244 GLN   B NE2 1 ? 
ATOM   4273 N N   . ASP   B 1 245 ? -4.814  -37.331 18.129 1.000 22.487 0 245 ASP   B N   1 ? 
ATOM   4274 C CA  . ASP   B 1 245 ? -4.708  -36.580 19.370 1.000 25.785 0 245 ASP   B CA  1 ? 
ATOM   4275 C C   . ASP   B 1 245 ? -4.301  -35.132 19.084 1.000 24.727 0 245 ASP   B C   1 ? 
ATOM   4276 O O   . ASP   B 1 245 ? -4.797  -34.221 19.742 1.000 23.334 0 245 ASP   B O   1 ? 
ATOM   4277 C CB  . ASP   B 1 245 ? -3.767  -37.215 20.395 1.000 30.256 0 245 ASP   B CB  1 ? 
ATOM   4278 C CG  . ASP   B 1 245 ? -3.961  -36.615 21.793 1.000 42.607 0 245 ASP   B CG  1 ? 
ATOM   4279 O OD1 . ASP   B 1 245 ? -5.097  -36.712 22.339 1.000 43.525 0 245 ASP   B OD1 1 ? 
ATOM   4280 O OD2 . ASP   B 1 245 ? -3.000  -35.997 22.328 1.000 45.399 0 245 ASP   B OD2 1 ? 
ATOM   4281 N N   . HIS   B 1 246 ? -3.384  -34.926 18.128 1.000 21.205 0 246 HIS   B N   1 ? 
ATOM   4282 C CA  . HIS   B 1 246 ? -2.995  -33.585 17.722 1.000 19.893 0 246 HIS   B CA  1 ? 
ATOM   4283 C C   . HIS   B 1 246 ? -4.229  -32.831 17.205 1.000 17.734 0 246 HIS   B C   1 ? 
ATOM   4284 O O   . HIS   B 1 246 ? -4.470  -31.695 17.586 1.000 15.546 0 246 HIS   B O   1 ? 
ATOM   4285 C CB  . HIS   B 1 246 ? -1.884  -33.660 16.668 1.000 20.042 0 246 HIS   B CB  1 ? 
ATOM   4286 C CG  . HIS   B 1 246 ? -0.566  -34.174 17.141 1.000 20.402 0 246 HIS   B CG  1 ? 
ATOM   4287 N ND1 . HIS   B 1 246 ? -0.122  -34.076 18.455 1.000 23.327 0 246 HIS   B ND1 1 ? 
ATOM   4288 C CD2 . HIS   B 1 246 ? 0.429   -34.756 16.458 1.000 19.836 0 246 HIS   B CD2 1 ? 
ATOM   4289 C CE1 . HIS   B 1 246 ? 1.096   -34.613 18.554 1.000 21.093 0 246 HIS   B CE1 1 ? 
ATOM   4290 N NE2 . HIS   B 1 246 ? 1.459   -35.028 17.354 1.000 21.729 0 246 HIS   B NE2 1 ? 
ATOM   4291 N N   . VAL   B 1 247 ? -5.003  -33.464 16.319 1.000 16.842 0 247 VAL   B N   1 ? 
ATOM   4292 C CA  . VAL   B 1 247 ? -6.207  -32.866 15.765 1.000 17.933 0 247 VAL   B CA  1 ? 
ATOM   4293 C C   . VAL   B 1 247 ? -7.131  -32.448 16.912 1.000 18.843 0 247 VAL   B C   1 ? 
ATOM   4294 O O   . VAL   B 1 247 ? -7.672  -31.342 16.913 1.000 16.618 0 247 VAL   B O   1 ? 
ATOM   4295 C CB  . VAL   B 1 247 ? -6.893  -33.842 14.779 1.000 19.125 0 247 VAL   B CB  1 ? 
ATOM   4296 C CG1 . VAL   B 1 247 ? -8.272  -33.367 14.342 1.000 20.057 0 247 VAL   B CG1 1 ? 
ATOM   4297 C CG2 . VAL   B 1 247 ? -6.035  -34.101 13.556 1.000 18.789 0 247 VAL   B CG2 1 ? 
ATOM   4298 N N   . ASP   B 1 248 ? -7.279  -33.330 17.914 1.000 18.866 0 248 ASP   B N   1 ? 
ATOM   4299 C CA  . ASP   B 1 248 ? -8.168  -33.082 19.034 1.000 20.036 0 248 ASP   B CA  1 ? 
ATOM   4300 C C   . ASP   B 1 248 ? -7.691  -31.857 19.803 1.000 18.095 0 248 ASP   B C   1 ? 
ATOM   4301 O O   . ASP   B 1 248 ? -8.484  -31.017 20.186 1.000 16.970 0 248 ASP   B O   1 ? 
ATOM   4302 C CB  . ASP   B 1 248 ? -8.259  -34.311 19.959 1.000 23.356 0 248 ASP   B CB  1 ? 
ATOM   4303 C CG  . ASP   B 1 248 ? -9.034  -35.481 19.376 1.000 24.745 0 248 ASP   B CG  1 ? 
ATOM   4304 O OD1 . ASP   B 1 248 ? -9.692  -35.307 18.331 1.000 26.184 0 248 ASP   B OD1 1 ? 
ATOM   4305 O OD2 . ASP   B 1 248 ? -8.949  -36.576 19.962 1.000 36.599 0 248 ASP   B OD2 1 ? 
ATOM   4306 N N   . ILE   B 1 249 ? -6.386  -31.775 20.026 1.000 18.874 0 249 ILE   B N   1 ? 
ATOM   4307 C CA  . ILE   B 1 249 ? -5.766  -30.720 20.819 1.000 19.531 0 249 ILE   B CA  1 ? 
ATOM   4308 C C   . ILE   B 1 249 ? -5.937  -29.350 20.142 1.000 17.797 0 249 ILE   B C   1 ? 
ATOM   4309 O O   . ILE   B 1 249 ? -5.920  -28.319 20.810 1.000 16.378 0 249 ILE   B O   1 ? 
ATOM   4310 C CB  . ILE   B 1 249 ? -4.278  -31.080 21.038 1.000 22.309 0 249 ILE   B CB  1 ? 
ATOM   4311 C CG1 . ILE   B 1 249 ? -4.111  -32.218 22.055 1.000 26.141 0 249 ILE   B CG1 1 ? 
ATOM   4312 C CG2 . ILE   B 1 249 ? -3.452  -29.859 21.432 1.000 21.938 0 249 ILE   B CG2 1 ? 
ATOM   4313 C CD1 . ILE   B 1 249 ? -2.720  -32.885 22.039 1.000 28.307 0 249 ILE   B CD1 1 ? 
ATOM   4314 N N   . LEU   B 1 250 ? -6.028  -29.341 18.810 1.000 16.489 0 250 LEU   B N   1 ? 
ATOM   4315 C CA  . LEU   B 1 250 ? -6.203  -28.119 18.027 1.000 16.537 0 250 LEU   B CA  1 ? 
ATOM   4316 C C   . LEU   B 1 250 ? -7.681  -27.698 17.982 1.000 17.468 0 250 LEU   B C   1 ? 
ATOM   4317 O O   . LEU   B 1 250 ? -7.997  -26.663 17.412 1.000 17.007 0 250 LEU   B O   1 ? 
ATOM   4318 C CB  . LEU   B 1 250 ? -5.683  -28.382 16.608 1.000 15.536 0 250 LEU   B CB  1 ? 
ATOM   4319 C CG  . LEU   B 1 250 ? -4.171  -28.406 16.430 1.000 15.010 0 250 LEU   B CG  1 ? 
ATOM   4320 C CD1 . LEU   B 1 250 ? -3.779  -28.983 15.091 1.000 15.358 0 250 LEU   B CD1 1 ? 
ATOM   4321 C CD2 . LEU   B 1 250 ? -3.579  -27.013 16.576 1.000 15.675 0 250 LEU   B CD2 1 ? 
ATOM   4322 N N   . GLY   B 1 251 ? -8.590  -28.501 18.561 1.000 17.814 0 251 GLY   B N   1 ? 
ATOM   4323 C CA  . GLY   B 1 251 ? -10.024 -28.230 18.518 1.000 17.579 0 251 GLY   B CA  1 ? 
ATOM   4324 C C   . GLY   B 1 251 ? -10.411 -26.834 19.014 1.000 17.566 0 251 GLY   B C   1 ? 
ATOM   4325 O O   . GLY   B 1 251 ? -11.268 -26.196 18.413 1.000 18.245 0 251 GLY   B O   1 ? 
ATOM   4326 N N   . PRO   B 1 252 ? -9.912  -26.335 20.171 1.000 16.386 0 252 PRO   B N   1 ? 
ATOM   4327 C CA  . PRO   B 1 252 ? -10.231 -24.967 20.591 1.000 17.404 0 252 PRO   B CA  1 ? 
ATOM   4328 C C   . PRO   B 1 252 ? -9.931  -23.896 19.541 1.000 17.723 0 252 PRO   B C   1 ? 
ATOM   4329 O O   . PRO   B 1 252 ? -10.770 -23.028 19.297 1.000 17.323 0 252 PRO   B O   1 ? 
ATOM   4330 C CB  . PRO   B 1 252 ? -9.405  -24.790 21.872 1.000 18.194 0 252 PRO   B CB  1 ? 
ATOM   4331 C CG  . PRO   B 1 252 ? -9.275  -26.202 22.427 1.000 18.502 0 252 PRO   B CG  1 ? 
ATOM   4332 C CD  . PRO   B 1 252 ? -9.207  -27.100 21.211 1.000 17.421 0 252 PRO   B CD  1 ? 
ATOM   4333 N N   . LEU   B 1 253 ? -8.747  -23.977 18.903 1.000 16.378 0 253 LEU   B N   1 ? 
ATOM   4334 C CA  . LEU   B 1 253 ? -8.317  -22.989 17.912 1.000 15.322 0 253 LEU   B CA  1 ? 
ATOM   4335 C C   . LEU   B 1 253 ? -9.145  -23.116 16.636 1.000 15.470 0 253 LEU   B C   1 ? 
ATOM   4336 O O   . LEU   B 1 253 ? -9.451  -22.125 15.981 1.000 14.401 0 253 LEU   B O   1 ? 
ATOM   4337 C CB  . LEU   B 1 253 ? -6.830  -23.202 17.627 1.000 14.202 0 253 LEU   B CB  1 ? 
ATOM   4338 C CG  . LEU   B 1 253 ? -5.928  -22.685 18.750 1.000 14.151 0 253 LEU   B CG  1 ? 
ATOM   4339 C CD1 . LEU   B 1 253 ? -4.467  -23.003 18.465 1.000 14.002 0 253 LEU   B CD1 1 ? 
ATOM   4340 C CD2 . LEU   B 1 253 ? -6.135  -21.185 18.938 1.000 14.875 0 253 LEU   B CD2 1 ? 
ATOM   4341 N N   . SER   B 1 254 ? -9.476  -24.359 16.292 1.000 15.013 0 254 SER   B N   1 ? 
ATOM   4342 C CA  . SER   B 1 254 ? -10.342 -24.667 15.175 1.000 16.696 0 254 SER   B CA  1 ? 
ATOM   4343 C C   . SER   B 1 254 ? -11.736 -24.060 15.411 1.000 16.958 0 254 SER   B C   1 ? 
ATOM   4344 O O   . SER   B 1 254 ? -12.316 -23.430 14.545 1.000 16.176 0 254 SER   B O   1 ? 
ATOM   4345 C CB  . SER   B 1 254 ? -10.398 -26.181 14.986 1.000 15.077 0 254 SER   B CB  1 ? 
ATOM   4346 O OG  . SER   B 1 254 ? -11.078 -26.481 13.789 1.000 17.460 0 254 SER   B OG  1 ? 
ATOM   4347 N N   . ALA   B 1 255 ? -12.287 -24.284 16.602 1.000 17.585 0 255 ALA   B N   1 ? 
ATOM   4348 C CA  . ALA   B 1 255 ? -13.589 -23.741 16.969 1.000 18.123 0 255 ALA   B CA  1 ? 
ATOM   4349 C C   . ALA   B 1 255 ? -13.543 -22.205 17.008 1.000 18.435 0 255 ALA   B C   1 ? 
ATOM   4350 O O   . ALA   B 1 255 ? -14.458 -21.556 16.516 1.000 18.119 0 255 ALA   B O   1 ? 
ATOM   4351 C CB  . ALA   B 1 255 ? -14.027 -24.320 18.291 1.000 17.130 0 255 ALA   B CB  1 ? 
ATOM   4352 N N   . GLN   B 1 256 ? -12.448 -21.617 17.506 1.000 17.644 0 256 GLN   B N   1 ? 
ATOM   4353 C CA  . GLN   B 1 256 ? -12.375 -20.168 17.658 1.000 19.604 0 256 GLN   B CA  1 ? 
ATOM   4354 C C   . GLN   B 1 256 ? -12.395 -19.469 16.296 1.000 17.714 0 256 GLN   B C   1 ? 
ATOM   4355 O O   . GLN   B 1 256 ? -13.029 -18.439 16.157 1.000 17.138 0 256 GLN   B O   1 ? 
ATOM   4356 C CB  . GLN   B 1 256 ? -11.115 -19.775 18.438 1.000 24.432 0 256 GLN   B CB  1 ? 
ATOM   4357 C CG  . GLN   B 1 256 ? -10.991 -18.283 18.747 1.000 28.956 0 256 GLN   B CG  1 ? 
ATOM   4358 C CD  . GLN   B 1 256 ? -9.754  -17.994 19.565 1.000 32.934 0 256 GLN   B CD  1 ? 
ATOM   4359 O OE1 . GLN   B 1 256 ? -9.146  -18.889 20.144 1.000 40.710 0 256 GLN   B OE1 1 ? 
ATOM   4360 N NE2 . GLN   B 1 256 ? -9.362  -16.735 19.628 1.000 35.686 0 256 GLN   B NE2 1 ? 
ATOM   4361 N N   . THR   B 1 257 ? -11.698 -20.021 15.291 1.000 16.113 0 257 THR   B N   1 ? 
ATOM   4362 C CA  . THR   B 1 257 ? -11.564 -19.399 13.985 1.000 16.408 0 257 THR   B CA  1 ? 
ATOM   4363 C C   . THR   B 1 257 ? -12.619 -19.933 13.024 1.000 16.688 0 257 THR   B C   1 ? 
ATOM   4364 O O   . THR   B 1 257 ? -12.940 -19.268 12.052 1.000 16.314 0 257 THR   B O   1 ? 
ATOM   4365 C CB  . THR   B 1 257 ? -10.164 -19.655 13.425 1.000 16.684 0 257 THR   B CB  1 ? 
ATOM   4366 O OG1 . THR   B 1 257 ? -9.964  -21.065 13.356 1.000 14.801 0 257 THR   B OG1 1 ? 
ATOM   4367 C CG2 . THR   B 1 257 ? -9.105  -19.036 14.310 1.000 17.140 0 257 THR   B CG2 1 ? 
ATOM   4368 N N   . GLY   B 1 258 ? -13.165 -21.119 13.314 1.000 15.743 0 258 GLY   B N   1 ? 
ATOM   4369 C CA  . GLY   B 1 258 ? -14.163 -21.725 12.457 1.000 16.239 0 258 GLY   B CA  1 ? 
ATOM   4370 C C   . GLY   B 1 258 ? -13.521 -22.484 11.302 1.000 16.800 0 258 GLY   B C   1 ? 
ATOM   4371 O O   . GLY   B 1 258 ? -14.211 -22.861 10.369 1.000 17.238 0 258 GLY   B O   1 ? 
ATOM   4372 N N   . ILE   B 1 259 ? -12.199 -22.707 11.364 1.000 16.892 0 259 ILE   B N   1 ? 
ATOM   4373 C CA  . ILE   B 1 259 ? -11.479 -23.406 10.302 1.000 15.453 0 259 ILE   B CA  1 ? 
ATOM   4374 C C   . ILE   B 1 259 ? -11.099 -24.788 10.808 1.000 14.148 0 259 ILE   B C   1 ? 
ATOM   4375 O O   . ILE   B 1 259 ? -10.350 -24.902 11.783 1.000 12.688 0 259 ILE   B O   1 ? 
ATOM   4376 C CB  . ILE   B 1 259 ? -10.249 -22.587 9.858  1.000 17.069 0 259 ILE   B CB  1 ? 
ATOM   4377 C CG1 . ILE   B 1 259 ? -10.664 -21.219 9.310  1.000 17.992 0 259 ILE   B CG1 1 ? 
ATOM   4378 C CG2 . ILE   B 1 259 ? -9.429  -23.338 8.808  1.000 16.582 0 259 ILE   B CG2 1 ? 
ATOM   4379 C CD1 . ILE   B 1 259 ? -9.525  -20.256 9.255  1.000 20.185 0 259 ILE   B CD1 1 ? 
ATOM   4380 N N   . ALA   B 1 260 ? -11.655 -25.828 10.159 1.000 14.127 0 260 ALA   B N   1 ? 
ATOM   4381 C CA  . ALA   B 1 260 ? -11.411 -27.211 10.547 1.000 13.883 0 260 ALA   B CA  1 ? 
ATOM   4382 C C   . ALA   B 1 260 ? -9.926  -27.505 10.341 1.000 13.883 0 260 ALA   B C   1 ? 
ATOM   4383 O O   . ALA   B 1 260 ? -9.267  -26.890 9.486  1.000 11.978 0 260 ALA   B O   1 ? 
ATOM   4384 C CB  . ALA   B 1 260 ? -12.284 -28.182 9.744  1.000 14.616 0 260 ALA   B CB  1 ? 
ATOM   4385 N N   . VAL   B 1 261 ? -9.412  -28.414 11.174 1.000 13.037 0 261 VAL   B N   1 ? 
ATOM   4386 C CA  . VAL   B 1 261 ? -8.010  -28.756 11.180 1.000 14.717 0 261 VAL   B CA  1 ? 
ATOM   4387 C C   . VAL   B 1 261 ? -7.564  -29.250 9.798  1.000 14.549 0 261 VAL   B C   1 ? 
ATOM   4388 O O   . VAL   B 1 261 ? -6.512  -28.846 9.311  1.000 13.860 0 261 VAL   B O   1 ? 
ATOM   4389 C CB  . VAL   B 1 261 ? -7.707  -29.767 12.305 1.000 15.064 0 261 VAL   B CB  1 ? 
ATOM   4390 C CG1 . VAL   B 1 261 ? -6.303  -30.344 12.154 1.000 14.939 0 261 VAL   B CG1 1 ? 
ATOM   4391 C CG2 . VAL   B 1 261 ? -7.881  -29.131 13.682 1.000 14.903 0 261 VAL   B CG2 1 ? 
ATOM   4392 N N   . LEU   B 1 262 ? -8.394  -30.060 9.139  1.000 14.591 0 262 LEU   B N   1 ? 
ATOM   4393 C CA  . LEU   B 1 262 ? -8.081  -30.622 7.830  1.000 15.381 0 262 LEU   B CA  1 ? 
ATOM   4394 C C   . LEU   B 1 262 ? -8.243  -29.614 6.692  1.000 15.025 0 262 LEU   B C   1 ? 
ATOM   4395 O O   . LEU   B 1 262 ? -7.773  -29.848 5.582  1.000 15.284 0 262 LEU   B O   1 ? 
ATOM   4396 C CB  . LEU   B 1 262 ? -8.984  -31.842 7.608  1.000 16.661 0 262 LEU   B CB  1 ? 
ATOM   4397 C CG  . LEU   B 1 262 ? -8.644  -33.030 8.512  1.000 17.514 0 262 LEU   B CG  1 ? 
ATOM   4398 C CD1 . LEU   B 1 262 ? -9.571  -34.221 8.243  1.000 18.807 0 262 LEU   B CD1 1 ? 
ATOM   4399 C CD2 . LEU   B 1 262 ? -7.181  -33.430 8.352  1.000 17.793 0 262 LEU   B CD2 1 ? 
ATOM   4400 N N   . ASP   B 1 263 ? -8.950  -28.518 6.959  1.000 15.437 0 263 ASP   B N   1 ? 
ATOM   4401 C CA  . ASP   B 1 263 ? -8.995  -27.352 6.090  1.000 14.223 0 263 ASP   B CA  1 ? 
ATOM   4402 C C   . ASP   B 1 263 ? -7.654  -26.624 6.216  1.000 13.534 0 263 ASP   B C   1 ? 
ATOM   4403 O O   . ASP   B 1 263 ? -6.963  -26.388 5.258  1.000 14.714 0 263 ASP   B O   1 ? 
ATOM   4404 C CB  . ASP   B 1 263 ? -10.226 -26.554 6.525  1.000 14.534 0 263 ASP   B CB  1 ? 
ATOM   4405 C CG  . ASP   B 1 263 ? -10.496 -25.242 5.827  1.000 16.170 0 263 ASP   B CG  1 ? 
ATOM   4406 O OD1 . ASP   B 1 263 ? -9.669  -24.793 5.051  1.000 17.732 0 263 ASP   B OD1 1 ? 
ATOM   4407 O OD2 . ASP   B 1 263 ? -11.564 -24.690 6.086  1.000 20.265 0 263 ASP   B OD2 1 ? 
ATOM   4408 N N   . MET   B 1 264 ? -7.241  -26.319 7.442  1.000 13.950 0 264 MET   B N   1 ? 
ATOM   4409 C CA  . MET   B 1 264 ? -5.984  -25.650 7.679  1.000 13.837 0 264 MET   B CA  1 ? 
ATOM   4410 C C   . MET   B 1 264 ? -4.819  -26.481 7.141  1.000 13.450 0 264 MET   B C   1 ? 
ATOM   4411 O O   . MET   B 1 264 ? -3.865  -25.909 6.637  1.000 13.328 0 264 MET   B O   1 ? 
ATOM   4412 C CB  . MET   B 1 264 ? -5.786  -25.414 9.184  1.000 13.988 0 264 MET   B CB  1 ? 
ATOM   4413 C CG  . MET   B 1 264 ? -4.568  -24.561 9.511  1.000 15.054 0 264 MET   B CG  1 ? 
ATOM   4414 S SD  . MET   B 1 264 ? -4.664  -22.873 8.807  1.000 17.195 0 264 MET   B SD  1 ? 
ATOM   4415 C CE  . MET   B 1 264 ? -5.531  -22.031 10.127 1.000 17.284 0 264 MET   B CE  1 ? 
ATOM   4416 N N   . CYS   B 1 265 ? -4.874  -27.817 7.291  1.000 13.776 0 265 CYS   B N   1 ? 
ATOM   4417 C CA  . CYS   B 1 265 ? -3.836  -28.720 6.810  1.000 14.407 0 265 CYS   B CA  1 ? 
ATOM   4418 C C   . CYS   B 1 265 ? -3.593  -28.578 5.304  1.000 14.886 0 265 CYS   B C   1 ? 
ATOM   4419 O O   . CYS   B 1 265 ? -2.466  -28.781 4.839  1.000 15.134 0 265 CYS   B O   1 ? 
ATOM   4420 C CB  . CYS   B 1 265 ? -4.179  -30.171 7.112  1.000 14.964 0 265 CYS   B CB  1 ? 
ATOM   4421 S SG  . CYS   B 1 265 ? -3.806  -30.644 8.820  1.000 16.600 0 265 CYS   B SG  1 ? 
ATOM   4422 N N   . ALA   B 1 266 ? -4.634  -28.244 4.531  1.000 13.688 0 266 ALA   B N   1 ? 
ATOM   4423 C CA  . ALA   B 1 266 ? -4.432  -28.058 3.100  1.000 14.607 0 266 ALA   B CA  1 ? 
ATOM   4424 C C   . ALA   B 1 266 ? -3.643  -26.770 2.859  1.000 14.471 0 266 ALA   B C   1 ? 
ATOM   4425 O O   . ALA   B 1 266 ? -2.854  -26.701 1.935  1.000 15.756 0 266 ALA   B O   1 ? 
ATOM   4426 C CB  . ALA   B 1 266 ? -5.750  -28.073 2.343  1.000 15.345 0 266 ALA   B CB  1 ? 
ATOM   4427 N N   . SER   B 1 267 ? -3.802  -25.758 3.714  1.000 15.613 0 267 SER   B N   1 ? 
ATOM   4428 C CA  . SER   B 1 267 ? -2.949  -24.571 3.637  1.000 15.796 0 267 SER   B CA  1 ? 
ATOM   4429 C C   . SER   B 1 267 ? -1.494  -24.952 3.844  1.000 14.903 0 267 SER   B C   1 ? 
ATOM   4430 O O   . SER   B 1 267 ? -0.614  -24.536 3.096  1.000 15.180 0 267 SER   B O   1 ? 
ATOM   4431 C CB  . SER   B 1 267 ? -3.343  -23.523 4.656  1.000 17.772 0 267 SER   B CB  1 ? 
ATOM   4432 O OG  . SER   B 1 267 ? -4.489  -22.818 4.253  1.000 19.204 0 267 SER   B OG  1 ? 
ATOM   4433 N N   . LEU   B 1 268 ? -1.255  -25.773 4.867  1.000 14.141 0 268 LEU   B N   1 ? 
ATOM   4434 C CA  . LEU   B 1 268 ? 0.094   -26.092 5.243  1.000 14.309 0 268 LEU   B CA  1 ? 
ATOM   4435 C C   . LEU   B 1 268 ? 0.726   -26.946 4.141  1.000 16.631 0 268 LEU   B C   1 ? 
ATOM   4436 O O   . LEU   B 1 268 ? 1.887   -26.724 3.782  1.000 17.456 0 268 LEU   B O   1 ? 
ATOM   4437 C CB  . LEU   B 1 268 ? 0.091   -26.756 6.624  1.000 13.908 0 268 LEU   B CB  1 ? 
ATOM   4438 C CG  . LEU   B 1 268 ? 1.443   -27.251 7.114  1.000 13.741 0 268 LEU   B CG  1 ? 
ATOM   4439 C CD1 . LEU   B 1 268 ? 2.456   -26.127 7.119  1.000 13.936 0 268 LEU   B CD1 1 ? 
ATOM   4440 C CD2 . LEU   B 1 268 ? 1.319   -27.866 8.495  1.000 13.901 0 268 LEU   B CD2 1 ? 
ATOM   4441 N N   . LYS   B 1 269 ? -0.056  -27.881 3.577  1.000 18.760 0 269 LYS   B N   1 ? 
ATOM   4442 C CA  . LYS   B 1 269 ? 0.409   -28.695 2.458  1.000 21.134 0 269 LYS   B CA  1 ? 
ATOM   4443 C C   . LYS   B 1 269 ? 0.853   -27.785 1.306  1.000 18.384 0 269 LYS   B C   1 ? 
ATOM   4444 O O   . LYS   B 1 269 ? 1.938   -27.949 0.766  1.000 17.175 0 269 LYS   B O   1 ? 
ATOM   4445 C CB  . LYS   B 1 269 ? -0.670  -29.718 2.088  1.000 24.199 0 269 LYS   B CB  1 ? 
ATOM   4446 C CG  . LYS   B 1 269 ? -0.429  -30.494 0.805  1.000 30.447 0 269 LYS   B CG  1 ? 
ATOM   4447 C CD  . LYS   B 1 269 ? -1.020  -31.907 0.796  1.000 33.286 0 269 LYS   B CD  1 ? 
ATOM   4448 C CE  . LYS   B 1 269 ? -2.528  -31.927 0.740  1.000 36.092 0 269 LYS   B CE  1 ? 
ATOM   4449 N NZ  . LYS   B 1 269 ? -3.045  -33.310 0.771  1.000 34.786 0 269 LYS   B NZ  1 ? 
ATOM   4450 N N   . GLU   B 1 270 ? 0.074   -26.740 1.012  1.000 19.245 0 270 GLU   B N   1 ? 
ATOM   4451 C CA  . GLU   B 1 270 ? 0.363   -25.860 -0.106 1.000 20.743 0 270 GLU   B CA  1 ? 
ATOM   4452 C C   . GLU   B 1 270 ? 1.606   -25.012 0.219  1.000 19.529 0 270 GLU   B C   1 ? 
ATOM   4453 O O   . GLU   B 1 270 ? 2.485   -24.841 -0.626 1.000 20.115 0 270 GLU   B O   1 ? 
ATOM   4454 C CB  . GLU   B 1 270 ? -0.883  -25.032 -0.437 1.000 24.998 0 270 GLU   B CB  1 ? 
ATOM   4455 C CG  . GLU   B 1 270 ? -1.027  -24.690 -1.912 1.000 34.429 0 270 GLU   B CG  1 ? 
ATOM   4456 C CD  . GLU   B 1 270 ? -2.083  -23.644 -2.266 1.000 40.971 0 270 GLU   B CD  1 ? 
ATOM   4457 O OE1 . GLU   B 1 270 ? -3.245  -24.033 -2.532 1.000 44.129 0 270 GLU   B OE1 1 ? 
ATOM   4458 O OE2 . GLU   B 1 270 ? -1.732  -22.447 -2.325 1.000 45.974 0 270 GLU   B OE2 1 ? 
ATOM   4459 N N   . LEU   B 1 271 ? 1.701   -24.491 1.446  1.000 17.083 0 271 LEU   B N   1 ? 
ATOM   4460 C CA  . LEU   B 1 271 ? 2.865   -23.731 1.867  1.000 16.918 0 271 LEU   B CA  1 ? 
ATOM   4461 C C   . LEU   B 1 271 ? 4.125   -24.591 1.778  1.000 17.774 0 271 LEU   B C   1 ? 
ATOM   4462 O O   . LEU   B 1 271 ? 5.159   -24.108 1.336  1.000 16.737 0 271 LEU   B O   1 ? 
ATOM   4463 C CB  . LEU   B 1 271 ? 2.653   -23.223 3.294  1.000 17.576 0 271 LEU   B CB  1 ? 
ATOM   4464 C CG  . LEU   B 1 271 ? 1.603   -22.122 3.466  1.000 17.801 0 271 LEU   B CG  1 ? 
ATOM   4465 C CD1 . LEU   B 1 271 ? 1.276   -21.884 4.938  1.000 18.024 0 271 LEU   B CD1 1 ? 
ATOM   4466 C CD2 . LEU   B 1 271 ? 2.081   -20.834 2.833  1.000 18.766 0 271 LEU   B CD2 1 ? 
ATOM   4467 N N   . LEU   B 1 272 ? 4.062   -25.861 2.201  1.000 19.121 0 272 LEU   B N   1 ? 
ATOM   4468 C CA  . LEU   B 1 272 ? 5.233   -26.724 2.096  1.000 18.908 0 272 LEU   B CA  1 ? 
ATOM   4469 C C   . LEU   B 1 272 ? 5.598   -26.944 0.632  1.000 19.704 0 272 LEU   B C   1 ? 
ATOM   4470 O O   . LEU   B 1 272 ? 6.769   -26.879 0.284  1.000 18.758 0 272 LEU   B O   1 ? 
ATOM   4471 C CB  . LEU   B 1 272 ? 4.978   -28.081 2.757  1.000 19.508 0 272 LEU   B CB  1 ? 
ATOM   4472 C CG  . LEU   B 1 272 ? 4.922   -28.068 4.269  1.000 20.208 0 272 LEU   B CG  1 ? 
ATOM   4473 C CD1 . LEU   B 1 272 ? 4.730   -29.470 4.785  1.000 21.648 0 272 LEU   B CD1 1 ? 
ATOM   4474 C CD2 . LEU   B 1 272 ? 6.188   -27.454 4.848  1.000 22.007 0 272 LEU   B CD2 1 ? 
ATOM   4475 N N   . GLN   B 1 273 ? 4.601   -27.236 -0.219 1.000 22.088 0 273 GLN   B N   1 ? 
ATOM   4476 C CA  . GLN   B 1 273 ? 4.892   -27.628 -1.600 1.000 23.734 0 273 GLN   B CA  1 ? 
ATOM   4477 C C   . GLN   B 1 273 ? 5.301   -26.441 -2.466 1.000 23.250 0 273 GLN   B C   1 ? 
ATOM   4478 O O   . GLN   B 1 273 ? 6.088   -26.628 -3.382 1.000 23.635 0 273 GLN   B O   1 ? 
ATOM   4479 C CB  . GLN   B 1 273 ? 3.712   -28.382 -2.213 1.000 23.404 0 273 GLN   B CB  1 ? 
ATOM   4480 C CG  . GLN   B 1 273 ? 3.541   -29.726 -1.531 1.000 25.863 0 273 GLN   B CG  1 ? 
ATOM   4481 C CD  . GLN   B 1 273 ? 2.443   -30.563 -2.136 1.000 28.207 0 273 GLN   B CD  1 ? 
ATOM   4482 O OE1 . GLN   B 1 273 ? 2.648   -31.727 -2.476 1.000 31.730 0 273 GLN   B OE1 1 ? 
ATOM   4483 N NE2 . GLN   B 1 273 ? 1.278   -29.970 -2.285 1.000 26.898 0 273 GLN   B NE2 1 ? 
ATOM   4484 N N   . ASN   B 1 274 ? 4.774   -25.241 -2.194 1.000 24.784 0 274 ASN   B N   1 ? 
ATOM   4485 C CA  . ASN   B 1 274 ? 4.967   -24.109 -3.088 1.000 26.676 0 274 ASN   B CA  1 ? 
ATOM   4486 C C   . ASN   B 1 274 ? 5.651   -22.922 -2.413 1.000 26.038 0 274 ASN   B C   1 ? 
ATOM   4487 O O   . ASN   B 1 274 ? 5.922   -21.934 -3.087 1.000 28.981 0 274 ASN   B O   1 ? 
ATOM   4488 C CB  . ASN   B 1 274 ? 3.648   -23.554 -3.631 1.000 30.228 0 274 ASN   B CB  1 ? 
ATOM   4489 C CG  . ASN   B 1 274 ? 2.811   -24.570 -4.369 1.000 33.235 0 274 ASN   B CG  1 ? 
ATOM   4490 O OD1 . ASN   B 1 274 ? 1.600   -24.632 -4.169 1.000 42.349 0 274 ASN   B OD1 1 ? 
ATOM   4491 N ND2 . ASN   B 1 274 ? 3.424   -25.330 -5.256 1.000 33.943 0 274 ASN   B ND2 1 ? 
ATOM   4492 N N   . GLY   B 1 275 ? 5.899   -22.981 -1.096 1.000 24.455 0 275 GLY   B N   1 ? 
ATOM   4493 C CA  . GLY   B 1 275 ? 6.532   -21.869 -0.402 1.000 24.706 0 275 GLY   B CA  1 ? 
ATOM   4494 C C   . GLY   B 1 275 ? 5.572   -20.691 -0.283 1.000 24.219 0 275 GLY   B C   1 ? 
ATOM   4495 O O   . GLY   B 1 275 ? 4.381   -20.845 -0.520 1.000 25.123 0 275 GLY   B O   1 ? 
ATOM   4496 N N   . MET   B 1 276 ? 6.087   -19.515 0.069  1.000 26.227 0 276 MET   B N   1 ? 
ATOM   4497 C CA  . MET   B 1 276 ? 5.223   -18.400 0.419  1.000 29.515 0 276 MET   B CA  1 ? 
ATOM   4498 C C   . MET   B 1 276 ? 5.070   -17.391 -0.721 1.000 30.369 0 276 MET   B C   1 ? 
ATOM   4499 O O   . MET   B 1 276 ? 4.250   -16.478 -0.631 1.000 28.855 0 276 MET   B O   1 ? 
ATOM   4500 C CB  . MET   B 1 276 ? 5.766   -17.702 1.664  1.000 29.643 0 276 MET   B CB  1 ? 
ATOM   4501 C CG  . MET   B 1 276 ? 5.458   -18.472 2.935  1.000 31.035 0 276 MET   B CG  1 ? 
ATOM   4502 S SD  . MET   B 1 276 ? 5.669   -17.462 4.410  1.000 35.496 0 276 MET   B SD  1 ? 
ATOM   4503 C CE  . MET   B 1 276 ? 6.033   -18.765 5.590  1.000 34.918 0 276 MET   B CE  1 ? 
ATOM   4504 N N   . ASN   B 1 277 ? 5.888   -17.529 -1.766 1.000 33.965 0 277 ASN   B N   1 ? 
ATOM   4505 C CA  . ASN   B 1 277 ? 5.852   -16.630 -2.911 1.000 38.408 0 277 ASN   B CA  1 ? 
ATOM   4506 C C   . ASN   B 1 277 ? 6.101   -15.188 -2.460 1.000 34.550 0 277 ASN   B C   1 ? 
ATOM   4507 O O   . ASN   B 1 277 ? 5.378   -14.272 -2.853 1.000 33.267 0 277 ASN   B O   1 ? 
ATOM   4508 C CB  . ASN   B 1 277 ? 4.540   -16.790 -3.683 1.000 47.296 0 277 ASN   B CB  1 ? 
ATOM   4509 C CG  . ASN   B 1 277 ? 4.658   -16.380 -5.138 1.000 58.167 0 277 ASN   B CG  1 ? 
ATOM   4510 O OD1 . ASN   B 1 277 ? 5.663   -15.799 -5.552 1.000 61.750 0 277 ASN   B OD1 1 ? 
ATOM   4511 N ND2 . ASN   B 1 277 ? 3.633   -16.673 -5.923 1.000 57.985 0 277 ASN   B ND2 1 ? 
ATOM   4512 N N   . GLY   B 1 278 ? 7.110   -15.016 -1.596 1.000 29.757 0 278 GLY   B N   1 ? 
ATOM   4513 C CA  . GLY   B 1 278 ? 7.555   -13.713 -1.140 1.000 28.038 0 278 GLY   B CA  1 ? 
ATOM   4514 C C   . GLY   B 1 278 ? 6.626   -13.043 -0.125 1.000 30.618 0 278 GLY   B C   1 ? 
ATOM   4515 O O   . GLY   B 1 278 ? 6.878   -11.897 0.236  1.000 31.630 0 278 GLY   B O   1 ? 
ATOM   4516 N N   . ARG   B 1 279 ? 5.576   -13.741 0.355  1.000 29.729 0 279 ARG   B N   1 ? 
ATOM   4517 C CA  . ARG   B 1 279 ? 4.707   -13.215 1.401  1.000 25.909 0 279 ARG   B CA  1 ? 
ATOM   4518 C C   . ARG   B 1 279 ? 5.276   -13.631 2.750  1.000 23.489 0 279 ARG   B C   1 ? 
ATOM   4519 O O   . ARG   B 1 279 ? 6.185   -14.444 2.803  1.000 25.468 0 279 ARG   B O   1 ? 
ATOM   4520 C CB  . ARG   B 1 279 ? 3.287   -13.779 1.324  1.000 27.809 0 279 ARG   B CB  1 ? 
ATOM   4521 C CG  . ARG   B 1 279 ? 2.628   -13.751 -0.047 1.000 30.037 0 279 ARG   B CG  1 ? 
ATOM   4522 C CD  . ARG   B 1 279 ? 1.939   -12.456 -0.404 1.000 28.261 0 279 ARG   B CD  1 ? 
ATOM   4523 N NE  . ARG   B 1 279 ? 1.006   -11.995 0.607  1.000 27.036 0 279 ARG   B NE  1 ? 
ATOM   4524 C CZ  . ARG   B 1 279 ? -0.309  -11.922 0.444  1.000 29.205 0 279 ARG   B CZ  1 ? 
ATOM   4525 N NH1 . ARG   B 1 279 ? -0.896  -12.547 -0.564 1.000 29.177 0 279 ARG   B NH1 1 ? 
ATOM   4526 N NH2 . ARG   B 1 279 ? -1.035  -11.258 1.325  1.000 27.506 0 279 ARG   B NH2 1 ? 
ATOM   4527 N N   . THR   B 1 280 ? 4.716   -13.076 3.829  1.000 21.476 0 280 THR   B N   1 ? 
ATOM   4528 C CA  . THR   B 1 280 ? 5.054   -13.449 5.188  1.000 20.037 0 280 THR   B CA  1 ? 
ATOM   4529 C C   . THR   B 1 280 ? 3.784   -13.774 5.967  1.000 18.921 0 280 THR   B C   1 ? 
ATOM   4530 O O   . THR   B 1 280 ? 2.691   -13.328 5.624  1.000 17.747 0 280 THR   B O   1 ? 
ATOM   4531 C CB  . THR   B 1 280 ? 5.822   -12.330 5.906  1.000 22.209 0 280 THR   B CB  1 ? 
ATOM   4532 O OG1 . THR   B 1 280 ? 4.987   -11.167 5.981  1.000 22.456 0 280 THR   B OG1 1 ? 
ATOM   4533 C CG2 . THR   B 1 280 ? 7.119   -11.974 5.211  1.000 22.183 0 280 THR   B CG2 1 ? 
ATOM   4534 N N   . ILE   B 1 281 ? 3.965   -14.521 7.065  1.000 17.756 0 281 ILE   B N   1 ? 
ATOM   4535 C CA  . ILE   B 1 281 ? 2.891   -14.852 7.980  1.000 16.140 0 281 ILE   B CA  1 ? 
ATOM   4536 C C   . ILE   B 1 281 ? 3.356   -14.387 9.343  1.000 16.162 0 281 ILE   B C   1 ? 
ATOM   4537 O O   . ILE   B 1 281 ? 4.384   -14.863 9.799  1.000 15.723 0 281 ILE   B O   1 ? 
ATOM   4538 C CB  . ILE   B 1 281 ? 2.592   -16.367 7.968  1.000 15.316 0 281 ILE   B CB  1 ? 
ATOM   4539 C CG1 . ILE   B 1 281 ? 2.125   -16.839 6.593  1.000 16.443 0 281 ILE   B CG1 1 ? 
ATOM   4540 C CG2 . ILE   B 1 281 ? 1.597   -16.715 9.068  1.000 15.637 0 281 ILE   B CG2 1 ? 
ATOM   4541 C CD1 . ILE   B 1 281 ? 1.997   -18.351 6.439  1.000 16.545 0 281 ILE   B CD1 1 ? 
ATOM   4542 N N   . LEU   B 1 282 ? 2.597   -13.476 9.965  1.000 18.272 0 282 LEU   B N   1 ? 
ATOM   4543 C CA  . LEU   B 1 282 ? 2.937   -12.892 11.256 1.000 19.170 0 282 LEU   B CA  1 ? 
ATOM   4544 C C   . LEU   B 1 282 ? 4.383   -12.375 11.234 1.000 20.810 0 282 LEU   B C   1 ? 
ATOM   4545 O O   . LEU   B 1 282 ? 5.137   -12.548 12.189 1.000 18.541 0 282 LEU   B O   1 ? 
ATOM   4546 C CB  . LEU   B 1 282 ? 2.679   -13.925 12.357 1.000 19.699 0 282 LEU   B CB  1 ? 
ATOM   4547 C CG  . LEU   B 1 282 ? 1.202   -14.140 12.721 1.000 21.102 0 282 LEU   B CG  1 ? 
ATOM   4548 C CD1 . LEU   B 1 282 ? 1.049   -15.231 13.782 1.000 20.214 0 282 LEU   B CD1 1 ? 
ATOM   4549 C CD2 . LEU   B 1 282 ? 0.559   -12.840 13.234 1.000 20.836 0 282 LEU   B CD2 1 ? 
ATOM   4550 N N   . GLY   B 1 283 ? 4.757   -11.801 10.082 1.000 20.827 0 283 GLY   B N   1 ? 
ATOM   4551 C CA  . GLY   B 1 283 ? 6.074   -11.239 9.849  1.000 23.359 0 283 GLY   B CA  1 ? 
ATOM   4552 C C   . GLY   B 1 283 ? 7.178   -12.272 9.597  1.000 23.424 0 283 GLY   B C   1 ? 
ATOM   4553 O O   . GLY   B 1 283 ? 8.355   -11.914 9.599  1.000 20.171 0 283 GLY   B O   1 ? 
ATOM   4554 N N   . SER   B 1 284 ? 6.830   -13.547 9.391  1.000 20.748 0 284 SER   B N   1 ? 
ATOM   4555 C CA  . SER   B 1 284 ? 7.875   -14.534 9.203  1.000 19.527 0 284 SER   B CA  1 ? 
ATOM   4556 C C   . SER   B 1 284 ? 7.838   -15.046 7.769  1.000 19.237 0 284 SER   B C   1 ? 
ATOM   4557 O O   . SER   B 1 284 ? 6.758   -15.208 7.171  1.000 16.533 0 284 SER   B O   1 ? 
ATOM   4558 C CB  . SER   B 1 284 ? 7.765   -15.646 10.234 1.000 22.302 0 284 SER   B CB  1 ? 
ATOM   4559 O OG  . SER   B 1 284 ? 8.715   -16.662 9.962  1.000 26.722 0 284 SER   B OG  1 ? 
ATOM   4560 N N   . ALA   B 1 285 ? 9.041   -15.273 7.200  1.000 19.252 0 285 ALA   B N   1 ? 
ATOM   4561 C CA  . ALA   B 1 285 ? 9.139   -15.891 5.892  1.000 19.082 0 285 ALA   B CA  1 ? 
ATOM   4562 C C   . ALA   B 1 285 ? 9.294   -17.397 6.038  1.000 19.689 0 285 ALA   B C   1 ? 
ATOM   4563 O O   . ALA   B 1 285 ? 9.222   -18.094 5.034  1.000 20.599 0 285 ALA   B O   1 ? 
ATOM   4564 C CB  . ALA   B 1 285 ? 10.276  -15.305 5.092  1.000 20.635 0 285 ALA   B CB  1 ? 
ATOM   4565 N N   . LEU   B 1 286 ? 9.487   -17.899 7.263  1.000 19.666 0 286 LEU   B N   1 ? 
ATOM   4566 C CA  . LEU   B 1 286 ? 9.504   -19.337 7.514  1.000 20.305 0 286 LEU   B CA  1 ? 
ATOM   4567 C C   . LEU   B 1 286 ? 8.342   -19.738 8.432  1.000 18.536 0 286 LEU   B C   1 ? 
ATOM   4568 O O   . LEU   B 1 286 ? 7.814   -18.900 9.142  1.000 16.611 0 286 LEU   B O   1 ? 
ATOM   4569 C CB  . LEU   B 1 286 ? 10.836  -19.702 8.180  1.000 23.327 0 286 LEU   B CB  1 ? 
ATOM   4570 C CG  . LEU   B 1 286 ? 12.102  -19.507 7.343  1.000 28.427 0 286 LEU   B CG  1 ? 
ATOM   4571 C CD1 . LEU   B 1 286 ? 13.347  -19.741 8.210  1.000 28.430 0 286 LEU   B CD1 1 ? 
ATOM   4572 C CD2 . LEU   B 1 286 ? 12.114  -20.412 6.116  1.000 27.412 0 286 LEU   B CD2 1 ? 
ATOM   4573 N N   . LEU   B 1 287 ? 8.020   -21.047 8.463  1.000 17.513 0 287 LEU   B N   1 ? 
ATOM   4574 C CA  . LEU   B 1 287 ? 6.926   -21.589 9.259  1.000 17.917 0 287 LEU   B CA  1 ? 
ATOM   4575 C C   . LEU   B 1 287 ? 7.462   -21.810 10.679 1.000 18.278 0 287 LEU   B C   1 ? 
ATOM   4576 O O   . LEU   B 1 287 ? 8.529   -22.371 10.863 1.000 18.837 0 287 LEU   B O   1 ? 
ATOM   4577 C CB  . LEU   B 1 287 ? 6.435   -22.897 8.625  1.000 17.920 0 287 LEU   B CB  1 ? 
ATOM   4578 C CG  . LEU   B 1 287 ? 5.994   -22.822 7.161  1.000 17.695 0 287 LEU   B CG  1 ? 
ATOM   4579 C CD1 . LEU   B 1 287 ? 5.669   -24.199 6.581  1.000 17.070 0 287 LEU   B CD1 1 ? 
ATOM   4580 C CD2 . LEU   B 1 287 ? 4.798   -21.909 7.008  1.000 17.831 0 287 LEU   B CD2 1 ? 
ATOM   4581 N N   . GLU   B 1 288 ? 6.757   -21.304 11.679 1.000 17.412 0 288 GLU   B N   1 ? 
ATOM   4582 C CA  . GLU   B 1 288 ? 7.257   -21.319 13.037 1.000 17.733 0 288 GLU   B CA  1 ? 
ATOM   4583 C C   . GLU   B 1 288 ? 6.640   -22.502 13.776 1.000 15.098 0 288 GLU   B C   1 ? 
ATOM   4584 O O   . GLU   B 1 288 ? 5.437   -22.734 13.668 1.000 13.055 0 288 GLU   B O   1 ? 
ATOM   4585 C CB  . GLU   B 1 288 ? 6.859   -20.013 13.707 1.000 20.964 0 288 GLU   B CB  1 ? 
ATOM   4586 C CG  . GLU   B 1 288 ? 7.098   -20.037 15.204 1.000 25.138 0 288 GLU   B CG  1 ? 
ATOM   4587 C CD  . GLU   B 1 288 ? 8.572   -19.926 15.583 1.000 30.472 0 288 GLU   B CD  1 ? 
ATOM   4588 O OE1 . GLU   B 1 288 ? 9.238   -18.990 15.034 1.000 33.937 0 288 GLU   B OE1 1 ? 
ATOM   4589 O OE2 . GLU   B 1 288 ? 9.051   -20.762 16.418 1.000 24.808 0 288 GLU   B OE2 1 ? 
ATOM   4590 N N   . ASP   B 1 289 ? 7.452   -23.204 14.567 1.000 14.347 0 289 ASP   B N   1 ? 
ATOM   4591 C CA  . ASP   B 1 289 ? 7.034   -24.449 15.189 1.000 15.067 0 289 ASP   B CA  1 ? 
ATOM   4592 C C   . ASP   B 1 289 ? 7.351   -24.439 16.686 1.000 15.456 0 289 ASP   B C   1 ? 
ATOM   4593 O O   . ASP   B 1 289 ? 7.241   -25.489 17.335 1.000 13.856 0 289 ASP   B O   1 ? 
ATOM   4594 C CB  . ASP   B 1 289 ? 7.641   -25.648 14.440 1.000 16.928 0 289 ASP   B CB  1 ? 
ATOM   4595 C CG  . ASP   B 1 289 ? 9.046   -26.077 14.857 1.000 17.229 0 289 ASP   B CG  1 ? 
ATOM   4596 O OD1 . ASP   B 1 289 ? 9.736   -25.230 15.470 1.000 16.244 0 289 ASP   B OD1 1 ? 
ATOM   4597 O OD2 . ASP   B 1 289 ? 9.429   -27.286 14.602 1.000 15.196 0 289 ASP   B OD2 1 ? 
ATOM   4598 N N   . GLU   B 1 290 ? 7.680   -23.257 17.255 1.000 14.508 0 290 GLU   B N   1 ? 
ATOM   4599 C CA  . GLU   B 1 290 ? 7.900   -23.188 18.696 1.000 15.997 0 290 GLU   B CA  1 ? 
ATOM   4600 C C   . GLU   B 1 290 ? 6.770   -22.454 19.434 1.000 15.657 0 290 GLU   B C   1 ? 
ATOM   4601 O O   . GLU   B 1 290 ? 6.995   -21.939 20.526 1.000 14.320 0 290 GLU   B O   1 ? 
ATOM   4602 C CB  . GLU   B 1 290 ? 9.301   -22.639 18.993 1.000 17.123 0 290 GLU   B CB  1 ? 
ATOM   4603 C CG  . GLU   B 1 290 ? 10.425  -23.526 18.430 1.000 18.868 0 290 GLU   B CG  1 ? 
ATOM   4604 C CD  . GLU   B 1 290 ? 11.744  -23.504 19.191 1.000 22.780 0 290 GLU   B CD  1 ? 
ATOM   4605 O OE1 . GLU   B 1 290 ? 11.906  -22.615 20.062 1.000 25.168 0 290 GLU   B OE1 1 ? 
ATOM   4606 O OE2 . GLU   B 1 290 ? 12.593  -24.406 18.948 1.000 22.567 0 290 GLU   B OE2 1 ? 
ATOM   4607 N N   . PHE   B 1 291 ? 5.540   -22.468 18.908 1.000 14.902 0 291 PHE   B N   1 ? 
ATOM   4608 C CA  . PHE   B 1 291 ? 4.384   -22.160 19.759 1.000 16.297 0 291 PHE   B CA  1 ? 
ATOM   4609 C C   . PHE   B 1 291 ? 3.455   -23.362 19.895 1.000 15.466 0 291 PHE   B C   1 ? 
ATOM   4610 O O   . PHE   B 1 291 ? 2.994   -23.881 18.886 1.000 15.380 0 291 PHE   B O   1 ? 
ATOM   4611 C CB  . PHE   B 1 291 ? 3.543   -21.016 19.182 1.000 17.648 0 291 PHE   B CB  1 ? 
ATOM   4612 C CG  . PHE   B 1 291 ? 4.286   -19.714 19.046 1.000 18.429 0 291 PHE   B CG  1 ? 
ATOM   4613 C CD1 . PHE   B 1 291 ? 5.051   -19.432 17.926 1.000 19.805 0 291 PHE   B CD1 1 ? 
ATOM   4614 C CD2 . PHE   B 1 291 ? 4.267   -18.799 20.080 1.000 21.576 0 291 PHE   B CD2 1 ? 
ATOM   4615 C CE1 . PHE   B 1 291 ? 5.751   -18.238 17.820 1.000 20.762 0 291 PHE   B CE1 1 ? 
ATOM   4616 C CE2 . PHE   B 1 291 ? 4.972   -17.606 19.981 1.000 21.812 0 291 PHE   B CE2 1 ? 
ATOM   4617 C CZ  . PHE   B 1 291 ? 5.704   -17.322 18.848 1.000 21.665 0 291 PHE   B CZ  1 ? 
ATOM   4618 N N   . THR   B 1 292 ? 3.129   -23.783 21.120 1.000 15.858 0 292 THR   B N   1 ? 
ATOM   4619 C CA  . THR   B 1 292 ? 2.128   -24.825 21.285 1.000 15.979 0 292 THR   B CA  1 ? 
ATOM   4620 C C   . THR   B 1 292 ? 0.718   -24.253 21.102 1.000 15.513 0 292 THR   B C   1 ? 
ATOM   4621 O O   . THR   B 1 292 ? 0.490   -23.042 21.131 1.000 14.807 0 292 THR   B O   1 ? 
ATOM   4622 C CB  . THR   B 1 292 ? 2.175   -25.515 22.655 1.000 17.398 0 292 THR   B CB  1 ? 
ATOM   4623 O OG1 . THR   B 1 292 ? 1.841   -24.482 23.584 1.000 18.090 0 292 THR   B OG1 1 ? 
ATOM   4624 C CG2 . THR   B 1 292 ? 3.496   -26.173 22.992 1.000 17.355 0 292 THR   B CG2 1 ? 
ATOM   4625 N N   . PRO   B 1 293 ? -0.292  -25.124 20.911 1.000 16.305 0 293 PRO   B N   1 ? 
ATOM   4626 C CA  . PRO   B 1 293 ? -1.689  -24.701 20.920 1.000 17.692 0 293 PRO   B CA  1 ? 
ATOM   4627 C C   . PRO   B 1 293 ? -2.036  -23.890 22.160 1.000 19.064 0 293 PRO   B C   1 ? 
ATOM   4628 O O   . PRO   B 1 293 ? -2.682  -22.852 22.055 1.000 19.380 0 293 PRO   B O   1 ? 
ATOM   4629 C CB  . PRO   B 1 293 ? -2.446  -26.025 20.782 1.000 18.443 0 293 PRO   B CB  1 ? 
ATOM   4630 C CG  . PRO   B 1 293 ? -1.496  -26.858 19.922 1.000 17.471 0 293 PRO   B CG  1 ? 
ATOM   4631 C CD  . PRO   B 1 293 ? -0.136  -26.535 20.510 1.000 17.568 0 293 PRO   B CD  1 ? 
ATOM   4632 N N   . PHE   B 1 294 ? -1.529  -24.314 23.315 1.000 22.510 0 294 PHE   B N   1 ? 
ATOM   4633 C CA  . PHE   B 1 294 ? -1.806  -23.616 24.556 1.000 22.216 0 294 PHE   B CA  1 ? 
ATOM   4634 C C   . PHE   B 1 294 ? -1.149  -22.234 24.559 1.000 21.549 0 294 PHE   B C   1 ? 
ATOM   4635 O O   . PHE   B 1 294 ? -1.774  -21.273 25.018 1.000 22.800 0 294 PHE   B O   1 ? 
ATOM   4636 C CB  . PHE   B 1 294 ? -1.407  -24.456 25.773 1.000 26.894 0 294 PHE   B CB  1 ? 
ATOM   4637 C CG  . PHE   B 1 294 ? -1.697  -23.745 27.075 1.000 34.755 0 294 PHE   B CG  1 ? 
ATOM   4638 C CD1 . PHE   B 1 294 ? -3.008  -23.529 27.489 1.000 36.862 0 294 PHE   B CD1 1 ? 
ATOM   4639 C CD2 . PHE   B 1 294 ? -0.661  -23.215 27.842 1.000 39.238 0 294 PHE   B CD2 1 ? 
ATOM   4640 C CE1 . PHE   B 1 294 ? -3.275  -22.840 28.664 1.000 38.563 0 294 PHE   B CE1 1 ? 
ATOM   4641 C CE2 . PHE   B 1 294 ? -0.928  -22.520 29.014 1.000 39.327 0 294 PHE   B CE2 1 ? 
ATOM   4642 C CZ  . PHE   B 1 294 ? -2.235  -22.336 29.421 1.000 40.284 0 294 PHE   B CZ  1 ? 
ATOM   4643 N N   . ASP   B 1 295 ? 0.096   -22.128 24.061 1.000 19.901 0 295 ASP   B N   1 ? 
ATOM   4644 C CA  . ASP   B 1 295 ? 0.773   -20.841 23.960 1.000 19.608 0 295 ASP   B CA  1 ? 
ATOM   4645 C C   . ASP   B 1 295 ? -0.092  -19.865 23.163 1.000 18.845 0 295 ASP   B C   1 ? 
ATOM   4646 O O   . ASP   B 1 295 ? -0.210  -18.723 23.551 1.000 17.941 0 295 ASP   B O   1 ? 
ATOM   4647 C CB  . ASP   B 1 295 ? 2.156   -20.961 23.325 1.000 20.227 0 295 ASP   B CB  1 ? 
ATOM   4648 C CG  . ASP   B 1 295 ? 3.143   -21.800 24.124 1.000 23.912 0 295 ASP   B CG  1 ? 
ATOM   4649 O OD1 . ASP   B 1 295 ? 2.934   -21.946 25.359 1.000 23.708 0 295 ASP   B OD1 1 ? 
ATOM   4650 O OD2 . ASP   B 1 295 ? 4.083   -22.358 23.489 1.000 23.029 0 295 ASP   B OD2 1 ? 
ATOM   4651 N N   . VAL   B 1 296 ? -0.703  -20.327 22.060 1.000 16.773 0 296 VAL   B N   1 ? 
ATOM   4652 C CA  . VAL   B 1 296 ? -1.466  -19.459 21.187 1.000 17.231 0 296 VAL   B CA  1 ? 
ATOM   4653 C C   . VAL   B 1 296 ? -2.713  -18.977 21.930 1.000 20.156 0 296 VAL   B C   1 ? 
ATOM   4654 O O   . VAL   B 1 296 ? -3.001  -17.788 21.919 1.000 20.894 0 296 VAL   B O   1 ? 
ATOM   4655 C CB  . VAL   B 1 296 ? -1.834  -20.175 19.877 1.000 16.032 0 296 VAL   B CB  1 ? 
ATOM   4656 C CG1 . VAL   B 1 296 ? -2.810  -19.378 19.036 1.000 16.019 0 296 VAL   B CG1 1 ? 
ATOM   4657 C CG2 . VAL   B 1 296 ? -0.585  -20.526 19.096 1.000 16.415 0 296 VAL   B CG2 1 ? 
ATOM   4658 N N   . VAL   B 1 297 ? -3.400  -19.908 22.594 1.000 22.492 0 297 VAL   B N   1 ? 
ATOM   4659 C CA  . VAL   B 1 297 ? -4.617  -19.639 23.341 1.000 26.187 0 297 VAL   B CA  1 ? 
ATOM   4660 C C   . VAL   B 1 297 ? -4.321  -18.640 24.462 1.000 27.162 0 297 VAL   B C   1 ? 
ATOM   4661 O O   . VAL   B 1 297 ? -5.047  -17.660 24.621 1.000 24.261 0 297 VAL   B O   1 ? 
ATOM   4662 C CB  . VAL   B 1 297 ? -5.198  -20.950 23.900 1.000 29.560 0 297 VAL   B CB  1 ? 
ATOM   4663 C CG1 . VAL   B 1 297 ? -6.270  -20.709 24.960 1.000 32.475 0 297 VAL   B CG1 1 ? 
ATOM   4664 C CG2 . VAL   B 1 297 ? -5.729  -21.846 22.794 1.000 29.229 0 297 VAL   B CG2 1 ? 
ATOM   4665 N N   . ARG   B 1 298 ? -3.223  -18.882 25.185 1.000 29.172 0 298 ARG   B N   1 ? 
ATOM   4666 C CA  . ARG   B 1 298 ? -2.784  -18.034 26.281 1.000 33.767 0 298 ARG   B CA  1 ? 
ATOM   4667 C C   . ARG   B 1 298 ? -2.594  -16.609 25.770 1.000 33.298 0 298 ARG   B C   1 ? 
ATOM   4668 O O   . ARG   B 1 298 ? -3.102  -15.651 26.345 1.000 32.600 0 298 ARG   B O   1 ? 
ATOM   4669 C CB  . ARG   B 1 298 ? -1.478  -18.561 26.895 1.000 38.777 0 298 ARG   B CB  1 ? 
ATOM   4670 C CG  . ARG   B 1 298 ? -1.105  -17.949 28.241 1.000 46.034 0 298 ARG   B CG  1 ? 
ATOM   4671 C CD  . ARG   B 1 298 ? 0.332   -18.219 28.703 1.000 55.714 0 298 ARG   B CD  1 ? 
ATOM   4672 N NE  . ARG   B 1 298 ? 1.249   -17.071 28.684 1.000 57.790 0 298 ARG   B NE  1 ? 
ATOM   4673 C CZ  . ARG   B 1 298 ? 2.540   -17.093 28.319 1.000 63.696 0 298 ARG   B CZ  1 ? 
ATOM   4674 N NH1 . ARG   B 1 298 ? 3.305   -16.031 28.527 1.000 54.913 0 298 ARG   B NH1 1 ? 
ATOM   4675 N NH2 . ARG   B 1 298 ? 3.084   -18.180 27.793 1.000 67.323 0 298 ARG   B NH2 1 ? 
ATOM   4676 N N   . GLN   B 1 299 ? -1.856  -16.467 24.674 1.000 30.953 0 299 GLN   B N   1 ? 
ATOM   4677 C CA  . GLN   B 1 299 ? -1.499  -15.137 24.221 1.000 30.094 0 299 GLN   B CA  1 ? 
ATOM   4678 C C   . GLN   B 1 299 ? -2.677  -14.463 23.513 1.000 30.260 0 299 GLN   B C   1 ? 
ATOM   4679 O O   . GLN   B 1 299 ? -2.803  -13.243 23.572 1.000 30.698 0 299 GLN   B O   1 ? 
ATOM   4680 C CB  . GLN   B 1 299 ? -0.267  -15.198 23.323 1.000 26.802 0 299 GLN   B CB  1 ? 
ATOM   4681 C CG  . GLN   B 1 299 ? -0.012  -13.882 22.618 1.000 26.292 0 299 GLN   B CG  1 ? 
ATOM   4682 C CD  . GLN   B 1 299 ? 1.406   -13.704 22.138 1.000 26.243 0 299 GLN   B CD  1 ? 
ATOM   4683 O OE1 . GLN   B 1 299 ? 1.722   -12.693 21.529 1.000 26.697 0 299 GLN   B OE1 1 ? 
ATOM   4684 N NE2 . GLN   B 1 299 ? 2.271   -14.676 22.381 1.000 25.192 0 299 GLN   B NE2 1 ? 
ATOM   4685 N N   . CYS   B 1 300 ? -3.523  -15.249 22.840 1.000 29.601 0 300 CYS   B N   1 ? 
ATOM   4686 C CA  . CYS   B 1 300 ? -4.645  -14.703 22.089 1.000 33.600 0 300 CYS   B CA  1 ? 
ATOM   4687 C C   . CYS   B 1 300 ? -5.901  -14.527 22.957 1.000 37.071 0 300 CYS   B C   1 ? 
ATOM   4688 O O   . CYS   B 1 300 ? -6.877  -13.958 22.484 1.000 39.132 0 300 CYS   B O   1 ? 
ATOM   4689 C CB  . CYS   B 1 300 ? -4.956  -15.571 20.876 1.000 32.514 0 300 CYS   B CB  1 ? 
ATOM   4690 S SG  . CYS   B 1 300 ? -3.690  -15.458 19.577 1.000 34.097 0 300 CYS   B SG  1 ? 
ATOM   4691 N N   . SER   B 1 301 ? -5.880  -14.981 24.220 1.000 40.075 0 301 SER   B N   1 ? 
ATOM   4692 C CA  . SER   B 1 301 ? -7.007  -14.795 25.129 1.000 46.971 0 301 SER   B CA  1 ? 
ATOM   4693 C C   . SER   B 1 301 ? -6.591  -13.998 26.372 1.000 52.112 0 301 SER   B C   1 ? 
ATOM   4694 O O   . SER   B 1 301 ? -7.437  -13.351 26.988 1.000 57.447 0 301 SER   B O   1 ? 
ATOM   4695 C CB  . SER   B 1 301 ? -7.621  -16.113 25.536 1.000 50.490 0 301 SER   B CB  1 ? 
ATOM   4696 O OG  . SER   B 1 301 ? -6.910  -16.674 26.642 1.000 51.970 0 301 SER   B OG  1 ? 
ATOM   4697 N N   . GLY   B 1 302 ? -5.317  -14.104 26.783 1.000 51.582 0 302 GLY   B N   1 ? 
ATOM   4698 C CA  . GLY   B 1 302 ? -4.691  -13.137 27.682 1.000 54.372 0 302 GLY   B CA  1 ? 
ATOM   4699 C C   . GLY   B 1 302 ? -4.668  -13.562 29.153 1.000 54.603 0 302 GLY   B C   1 ? 
ATOM   4700 O O   . GLY   B 1 302 ? -4.863  -12.719 30.025 1.000 47.764 0 302 GLY   B O   1 ? 
ATOM   4701 N N   . VAL   B 1 303 ? -4.402  -14.854 29.423 1.000 57.889 0 303 VAL   B N   1 ? 
ATOM   4702 C CA  . VAL   B 1 303 ? -4.419  -15.372 30.788 1.000 64.916 0 303 VAL   B CA  1 ? 
ATOM   4703 C C   . VAL   B 1 303 ? -3.199  -14.799 31.506 1.000 67.829 0 303 VAL   B C   1 ? 
ATOM   4704 O O   . VAL   B 1 303 ? -2.173  -14.547 30.870 1.000 64.268 0 303 VAL   B O   1 ? 
ATOM   4705 C CB  . VAL   B 1 303 ? -4.451  -16.918 30.903 1.000 65.190 0 303 VAL   B CB  1 ? 
ATOM   4706 C CG1 . VAL   B 1 303 ? -5.099  -17.602 29.704 1.000 66.053 0 303 VAL   B CG1 1 ? 
ATOM   4707 C CG2 . VAL   B 1 303 ? -3.074  -17.516 31.173 1.000 65.082 0 303 VAL   B CG2 1 ? 
ATOM   4708 N N   . THR   B 1 304 ? -3.308  -14.654 32.834 1.000 65.545 0 304 THR   B N   1 ? 
ATOM   4709 C CA  . THR   B 1 304 ? -2.355  -13.867 33.604 1.000 67.714 0 304 THR   B CA  1 ? 
ATOM   4710 C C   . THR   B 1 304 ? -1.887  -14.617 34.863 1.000 63.215 0 304 THR   B C   1 ? 
ATOM   4711 O O   . THR   B 1 304 ? -2.274  -15.790 35.026 1.000 58.087 0 304 THR   B O   1 ? 
ATOM   4712 C CB  . THR   B 1 304 ? -2.963  -12.495 33.929 1.000 63.595 0 304 THR   B CB  1 ? 
ATOM   4713 O OG1 . THR   B 1 304 ? -2.034  -11.826 34.776 1.000 71.312 0 304 THR   B OG1 1 ? 
ATOM   4714 C CG2 . THR   B 1 304 ? -4.316  -12.569 34.604 1.000 65.871 0 304 THR   B CG2 1 ? 
HETATM 4715 N N1  . A1H9E C 2 .   ? -8.537  2.376   21.699 1.000 22.244 0 401 A1H9E A N1  1 ? 
HETATM 4716 N N3  . A1H9E C 2 .   ? -6.755  0.832   24.184 1.000 19.054 0 401 A1H9E A N3  1 ? 
HETATM 4717 C C4  . A1H9E C 2 .   ? -8.681  1.604   19.414 1.000 22.613 0 401 A1H9E A C4  1 ? 
HETATM 4718 C C5  . A1H9E C 2 .   ? -7.936  1.834   20.569 1.000 22.215 0 401 A1H9E A C5  1 ? 
HETATM 4719 C C6  . A1H9E C 2 .   ? -8.563  0.585   17.206 1.000 28.258 0 401 A1H9E A C6  1 ? 
HETATM 4720 C C7  . A1H9E C 2 .   ? -7.965  -0.022  14.803 1.000 36.470 0 401 A1H9E A C7  1 ? 
HETATM 4721 C C8  . A1H9E C 2 .   ? -8.207  1.359   14.188 1.000 38.757 0 401 A1H9E A C8  1 ? 
HETATM 4722 C C10 . A1H9E C 2 .   ? -9.158  -0.950  14.619 1.000 36.403 0 401 A1H9E A C10 1 ? 
HETATM 4723 C C13 . A1H9E C 2 .   ? -7.837  1.183   23.554 1.000 21.139 0 401 A1H9E A C13 1 ? 
HETATM 4724 C C15 . A1H9E C 2 .   ? -7.704  6.281   23.735 1.000 25.703 0 401 A1H9E A C15 1 ? 
HETATM 4725 C C17 . A1H9E C 2 .   ? -6.138  -0.246  24.995 1.000 21.840 0 401 A1H9E A C17 1 ? 
HETATM 4726 C C20 . A1H9E C 2 .   ? -6.866  -1.030  27.395 1.000 19.037 0 401 A1H9E A C20 1 ? 
HETATM 4727 C C21 . A1H9E C 2 .   ? -6.064  -1.855  23.001 1.000 22.530 0 401 A1H9E A C21 1 ? 
HETATM 4728 C C22 . A1H9E C 2 .   ? -4.946  -2.694  22.424 1.000 22.602 0 401 A1H9E A C22 1 ? 
HETATM 4729 C C24 . A1H9E C 2 .   ? -7.330  -2.626  22.606 1.000 22.406 0 401 A1H9E A C24 1 ? 
HETATM 4730 O O7  . A1H9E C 2 .   ? -6.182  -2.024  27.401 1.000 19.924 0 401 A1H9E A O7  1 ? 
HETATM 4731 N N4  . A1H9E C 2 .   ? -7.862  -0.865  28.257 1.000 18.135 0 401 A1H9E A N4  1 ? 
HETATM 4732 C C19 . A1H9E C 2 .   ? -6.659  0.036   26.403 1.000 20.372 0 401 A1H9E A C19 1 ? 
HETATM 4733 O O6  . A1H9E C 2 .   ? -7.307  1.214   26.772 1.000 20.071 0 401 A1H9E A O6  1 ? 
HETATM 4734 C C18 . A1H9E C 2 .   ? -6.048  -1.685  24.502 1.000 21.254 0 401 A1H9E A C18 1 ? 
HETATM 4735 C C23 . A1H9E C 2 .   ? -6.918  -3.811  21.715 1.000 23.271 0 401 A1H9E A C23 1 ? 
HETATM 4736 N N5  . A1H9E C 2 .   ? -5.461  -3.745  21.814 1.000 22.044 0 401 A1H9E A N5  1 ? 
HETATM 4737 O O5  . A1H9E C 2 .   ? -3.770  -2.407  22.466 1.000 22.006 0 401 A1H9E A O5  1 ? 
HETATM 4738 O O4  . A1H9E C 2 .   ? -8.820  0.501   23.399 1.000 19.955 0 401 A1H9E A O4  1 ? 
HETATM 4739 C C11 . A1H9E C 2 .   ? -7.729  2.552   22.908 1.000 22.067 0 401 A1H9E A C11 1 ? 
HETATM 4740 C C12 . A1H9E C 2 .   ? -8.197  3.782   23.697 1.000 20.607 0 401 A1H9E A C12 1 ? 
HETATM 4741 C C14 . A1H9E C 2 .   ? -7.139  4.867   23.681 1.000 24.636 0 401 A1H9E A C14 1 ? 
HETATM 4742 C C16 . A1H9E C 2 .   ? -6.940  5.813   22.513 1.000 26.124 0 401 A1H9E A C16 1 ? 
HETATM 4743 O O2  . A1H9E C 2 .   ? -6.740  1.557   20.650 1.000 18.343 0 401 A1H9E A O2  1 ? 
HETATM 4744 C C3  . A1H9E C 2 .   ? -10.024 1.935   19.436 1.000 23.750 0 401 A1H9E A C3  1 ? 
HETATM 4745 C C2  . A1H9E C 2 .   ? -10.593 2.463   20.596 1.000 27.321 0 401 A1H9E A C2  1 ? 
HETATM 4746 F F1  . A1H9E C 2 .   ? -11.882 2.786   20.722 1.000 29.138 0 401 A1H9E A F1  1 ? 
HETATM 4747 C C1  . A1H9E C 2 .   ? -9.832  2.678   21.703 1.000 24.839 0 401 A1H9E A C1  1 ? 
HETATM 4748 N N2  . A1H9E C 2 .   ? -8.011  1.086   18.300 1.000 25.401 0 401 A1H9E A N2  1 ? 
HETATM 4749 O O3  . A1H9E C 2 .   ? -9.758  0.500   17.035 1.000 31.379 0 401 A1H9E A O3  1 ? 
HETATM 4750 O O1  . A1H9E C 2 .   ? -7.671  0.102   16.183 1.000 33.342 0 401 A1H9E A O1  1 ? 
HETATM 4751 C C9  . A1H9E C 2 .   ? -6.737  -0.672  14.199 1.000 39.867 0 401 A1H9E A C9  1 ? 
HETATM 4752 N N1  . A1H9E D 2 .   ? 30.626  -28.867 28.374 1.000 25.848 0 401 A1H9E B N1  1 ? 
HETATM 4753 N N3  . A1H9E D 2 .   ? 28.714  -26.514 30.047 1.000 19.550 0 401 A1H9E B N3  1 ? 
HETATM 4754 C C4  . A1H9E D 2 .   ? 31.150  -28.881 26.004 1.000 26.507 0 401 A1H9E B C4  1 ? 
HETATM 4755 C C5  . A1H9E D 2 .   ? 30.261  -28.577 27.048 1.000 27.348 0 401 A1H9E B C5  1 ? 
HETATM 4756 C C6  . A1H9E D 2 .   ? 31.432  -28.395 23.637 1.000 25.818 0 401 A1H9E B C6  1 ? 
HETATM 4757 C C7  . A1H9E D 2 .   ? 31.342  -27.550 21.252 1.000 27.511 0 401 A1H9E B C7  1 ? 
HETATM 4758 C C8  . A1H9E D 2 .   ? 32.403  -26.483 21.527 1.000 27.665 0 401 A1H9E B C8  1 ? 
HETATM 4759 C C10 . A1H9E D 2 .   ? 30.198  -26.960 20.410 1.000 27.027 0 401 A1H9E B C10 1 ? 
HETATM 4760 C C13 . A1H9E D 2 .   ? 29.845  -27.051 29.703 1.000 21.134 0 401 A1H9E B C13 1 ? 
HETATM 4761 C C15 . A1H9E D 2 .   ? 29.531  -31.575 31.823 1.000 25.632 0 401 A1H9E B C15 1 ? 
HETATM 4762 C C17 . A1H9E D 2 .   ? 28.125  -25.257 30.461 1.000 23.708 0 401 A1H9E B C17 1 ? 
HETATM 4763 C C20 . A1H9E D 2 .   ? 28.800  -23.724 32.512 1.000 19.454 0 401 A1H9E B C20 1 ? 
HETATM 4764 C C21 . A1H9E D 2 .   ? 28.336  -24.121 28.002 1.000 24.044 0 401 A1H9E B C21 1 ? 
HETATM 4765 C C22 . A1H9E D 2 .   ? 27.216  -23.517 27.187 1.000 22.759 0 401 A1H9E B C22 1 ? 
HETATM 4766 C C24 . A1H9E D 2 .   ? 29.535  -23.199 27.643 1.000 23.067 0 401 A1H9E B C24 1 ? 
HETATM 4767 O O7  . A1H9E D 2 .   ? 28.198  -22.742 32.158 1.000 18.943 0 401 A1H9E B O7  1 ? 
HETATM 4768 N N4  . A1H9E D 2 .   ? 29.658  -23.689 33.540 1.000 21.369 0 401 A1H9E B N4  1 ? 
HETATM 4769 C C19 . A1H9E D 2 .   ? 28.824  -25.018 31.810 1.000 20.171 0 401 A1H9E B C19 1 ? 
HETATM 4770 O O6  . A1H9E D 2 .   ? 29.163  -25.970 32.806 1.000 19.352 0 401 A1H9E B O6  1 ? 
HETATM 4771 C C18 . A1H9E D 2 .   ? 28.160  -24.030 29.521 1.000 23.523 0 401 A1H9E B C18 1 ? 
HETATM 4772 C C23 . A1H9E D 2 .   ? 29.099  -22.232 26.550 1.000 22.878 0 401 A1H9E B C23 1 ? 
HETATM 4773 N N5  . A1H9E D 2 .   ? 27.664  -22.475 26.487 1.000 22.561 0 401 A1H9E B N5  1 ? 
HETATM 4774 O O5  . A1H9E D 2 .   ? 26.088  -23.940 27.167 1.000 20.086 0 401 A1H9E B O5  1 ? 
HETATM 4775 O O4  . A1H9E D 2 .   ? 30.907  -26.525 29.598 1.000 17.655 0 401 A1H9E B O4  1 ? 
HETATM 4776 C C11 . A1H9E D 2 .   ? 29.684  -28.524 29.452 1.000 22.836 0 401 A1H9E B C11 1 ? 
HETATM 4777 C C12 . A1H9E D 2 .   ? 29.949  -29.236 30.780 1.000 22.432 0 401 A1H9E B C12 1 ? 
HETATM 4778 C C14 . A1H9E D 2 .   ? 28.982  -30.400 30.995 1.000 25.989 0 401 A1H9E B C14 1 ? 
HETATM 4779 C C16 . A1H9E D 2 .   ? 29.367  -31.657 30.309 1.000 26.406 0 401 A1H9E B C16 1 ? 
HETATM 4780 O O2  . A1H9E D 2 .   ? 29.146  -28.065 26.812 1.000 22.230 0 401 A1H9E B O2  1 ? 
HETATM 4781 C C3  . A1H9E D 2 .   ? 32.415  -29.420 26.289 1.000 26.296 0 401 A1H9E B C3  1 ? 
HETATM 4782 C C2  . A1H9E D 2 .   ? 32.760  -29.651 27.616 1.000 27.753 0 401 A1H9E B C2  1 ? 
HETATM 4783 F F1  . A1H9E D 2 .   ? 33.952  -30.191 27.973 1.000 26.673 0 401 A1H9E B F1  1 ? 
HETATM 4784 C C1  . A1H9E D 2 .   ? 31.857  -29.361 28.624 1.000 26.060 0 401 A1H9E B C1  1 ? 
HETATM 4785 N N2  . A1H9E D 2 .   ? 30.700  -28.540 24.731 1.000 25.872 0 401 A1H9E B N2  1 ? 
HETATM 4786 O O3  . A1H9E D 2 .   ? 32.629  -28.605 23.561 1.000 27.755 0 401 A1H9E B O3  1 ? 
HETATM 4787 O O1  . A1H9E D 2 .   ? 30.729  -27.968 22.467 1.000 26.025 0 401 A1H9E B O1  1 ? 
HETATM 4788 C C9  . A1H9E D 2 .   ? 31.996  -28.793 20.613 1.000 28.398 0 401 A1H9E B C9  1 ? 
HETATM 4789 O O   . HOH   E 3 .   ? -7.815  15.232  18.544 1.000 32.553 0 501 HOH   A O   1 ? 
HETATM 4790 O O   . HOH   E 3 .   ? -9.538  -2.705  30.119 1.000 24.479 0 502 HOH   A O   1 ? 
HETATM 4791 O O   . HOH   E 3 .   ? 8.592   13.529  27.742 1.000 22.178 0 503 HOH   A O   1 ? 
HETATM 4792 O O   . HOH   E 3 .   ? -0.568  -9.384  25.799 1.000 18.317 0 504 HOH   A O   1 ? 
HETATM 4793 O O   . HOH   E 3 .   ? -6.576  -4.882  33.018 1.000 19.703 0 505 HOH   A O   1 ? 
HETATM 4794 O O   . HOH   E 3 .   ? -8.341  16.948  26.796 1.000 22.751 0 506 HOH   A O   1 ? 
HETATM 4795 O O   . HOH   E 3 .   ? 6.718   6.931   8.263  1.000 32.534 0 507 HOH   A O   1 ? 
HETATM 4796 O O   . HOH   E 3 .   ? -8.736  -1.675  40.669 1.000 19.783 0 508 HOH   A O   1 ? 
HETATM 4797 O O   . HOH   E 3 .   ? 17.309  -9.346  22.985 1.000 19.471 0 509 HOH   A O   1 ? 
HETATM 4798 O O   . HOH   E 3 .   ? 3.943   -3.662  32.594 1.000 15.793 0 510 HOH   A O   1 ? 
HETATM 4799 O O   . HOH   E 3 .   ? -3.389  11.002  14.987 1.000 31.306 0 511 HOH   A O   1 ? 
HETATM 4800 O O   . HOH   E 3 .   ? -4.722  7.829   27.561 1.000 18.798 0 512 HOH   A O   1 ? 
HETATM 4801 O O   . HOH   E 3 .   ? 4.382   -0.011  12.235 1.000 22.176 0 513 HOH   A O   1 ? 
HETATM 4802 O O   . HOH   E 3 .   ? 5.497   1.664   52.501 1.000 28.585 0 514 HOH   A O   1 ? 
HETATM 4803 O O   . HOH   E 3 .   ? 12.057  8.020   12.681 1.000 27.739 0 515 HOH   A O   1 ? 
HETATM 4804 O O   . HOH   E 3 .   ? 13.137  8.005   10.035 1.000 28.421 0 516 HOH   A O   1 ? 
HETATM 4805 O O   . HOH   E 3 .   ? 9.692   7.682   30.143 1.000 19.171 0 517 HOH   A O   1 ? 
HETATM 4806 O O   . HOH   E 3 .   ? 8.505   -3.167  17.473 1.000 9.149  0 518 HOH   A O   1 ? 
HETATM 4807 O O   . HOH   E 3 .   ? 16.648  -3.513  25.004 1.000 19.355 0 519 HOH   A O   1 ? 
HETATM 4808 O O   . HOH   E 3 .   ? 3.908   7.439   12.199 1.000 13.053 0 520 HOH   A O   1 ? 
HETATM 4809 O O   . HOH   E 3 .   ? 18.762  -6.551  14.488 1.000 9.087  0 521 HOH   A O   1 ? 
HETATM 4810 O O   . HOH   E 3 .   ? -2.981  16.641  29.920 1.000 26.691 0 522 HOH   A O   1 ? 
HETATM 4811 O O   . HOH   E 3 .   ? 3.749   13.552  20.059 1.000 37.637 0 523 HOH   A O   1 ? 
HETATM 4812 O O   . HOH   E 3 .   ? 3.610   5.415   19.905 1.000 15.552 0 524 HOH   A O   1 ? 
HETATM 4813 O O   . HOH   E 3 .   ? 2.140   -6.050  16.587 1.000 27.842 0 525 HOH   A O   1 ? 
HETATM 4814 O O   . HOH   E 3 .   ? 1.321   7.677   54.671 1.000 39.463 0 526 HOH   A O   1 ? 
HETATM 4815 O O   . HOH   E 3 .   ? 19.465  1.490   16.981 1.000 19.798 0 527 HOH   A O   1 ? 
HETATM 4816 O O   . HOH   E 3 .   ? -0.676  13.185  21.915 1.000 18.003 0 528 HOH   A O   1 ? 
HETATM 4817 O O   . HOH   E 3 .   ? 37.303  -6.187  7.001  1.000 25.098 0 529 HOH   A O   1 ? 
HETATM 4818 O O   . HOH   E 3 .   ? 16.510  -6.646  21.341 1.000 23.218 0 530 HOH   A O   1 ? 
HETATM 4819 O O   . HOH   E 3 .   ? 1.261   13.203  23.706 1.000 21.977 0 531 HOH   A O   1 ? 
HETATM 4820 O O   . HOH   E 3 .   ? 7.413   11.700  18.733 1.000 27.485 0 532 HOH   A O   1 ? 
HETATM 4821 O O   . HOH   E 3 .   ? 9.529   5.354   8.862  1.000 24.110 0 533 HOH   A O   1 ? 
HETATM 4822 O O   . HOH   E 3 .   ? -3.965  1.928   51.638 1.000 29.636 0 534 HOH   A O   1 ? 
HETATM 4823 O O   . HOH   E 3 .   ? 4.999   0.218   6.475  1.000 27.344 0 535 HOH   A O   1 ? 
HETATM 4824 O O   . HOH   E 3 .   ? 27.999  -19.698 7.119  1.000 24.925 0 536 HOH   A O   1 ? 
HETATM 4825 O O   . HOH   E 3 .   ? -0.005  -6.008  48.337 1.000 41.477 0 537 HOH   A O   1 ? 
HETATM 4826 O O   . HOH   E 3 .   ? 20.018  2.937   10.864 1.000 15.549 0 538 HOH   A O   1 ? 
HETATM 4827 O O   . HOH   E 3 .   ? 4.560   18.159  26.087 1.000 39.955 0 539 HOH   A O   1 ? 
HETATM 4828 O O   . HOH   E 3 .   ? 6.963   -14.445 38.116 1.000 23.974 0 540 HOH   A O   1 ? 
HETATM 4829 O O   . HOH   E 3 .   ? 14.873  -9.258  4.850  1.000 22.523 0 541 HOH   A O   1 ? 
HETATM 4830 O O   . HOH   E 3 .   ? 30.003  -2.622  -2.650 1.000 24.862 0 542 HOH   A O   1 ? 
HETATM 4831 O O   . HOH   E 3 .   ? 6.160   17.320  28.872 1.000 36.006 0 543 HOH   A O   1 ? 
HETATM 4832 O O   . HOH   E 3 .   ? 14.830  -15.701 18.851 1.000 21.207 0 544 HOH   A O   1 ? 
HETATM 4833 O O   . HOH   E 3 .   ? 28.166  -16.935 20.910 1.000 32.950 0 545 HOH   A O   1 ? 
HETATM 4834 O O   . HOH   E 3 .   ? 17.719  0.341   23.585 1.000 20.089 0 546 HOH   A O   1 ? 
HETATM 4835 O O   . HOH   E 3 .   ? -11.295 -6.009  38.639 1.000 35.375 0 547 HOH   A O   1 ? 
HETATM 4836 O O   . HOH   E 3 .   ? -1.231  2.412   11.238 1.000 25.155 0 548 HOH   A O   1 ? 
HETATM 4837 O O   . HOH   E 3 .   ? 15.127  10.890  28.176 1.000 23.355 0 549 HOH   A O   1 ? 
HETATM 4838 O O   . HOH   E 3 .   ? -6.354  3.990   16.618 1.000 29.138 0 550 HOH   A O   1 ? 
HETATM 4839 O O   . HOH   E 3 .   ? -4.043  17.892  36.795 1.000 20.136 0 551 HOH   A O   1 ? 
HETATM 4840 O O   . HOH   E 3 .   ? 14.299  2.475   28.689 1.000 21.669 0 552 HOH   A O   1 ? 
HETATM 4841 O O   . HOH   E 3 .   ? 34.342  3.814   16.248 1.000 34.353 0 553 HOH   A O   1 ? 
HETATM 4842 O O   . HOH   E 3 .   ? 34.483  0.738   8.016  1.000 16.358 0 554 HOH   A O   1 ? 
HETATM 4843 O O   . HOH   E 3 .   ? 17.808  -13.943 15.256 1.000 30.462 0 555 HOH   A O   1 ? 
HETATM 4844 O O   . HOH   E 3 .   ? 23.426  0.423   20.762 1.000 18.282 0 556 HOH   A O   1 ? 
HETATM 4845 O O   . HOH   E 3 .   ? 24.338  -3.981  33.685 1.000 38.408 0 557 HOH   A O   1 ? 
HETATM 4846 O O   . HOH   E 3 .   ? 12.017  -15.632 8.748  1.000 22.703 0 558 HOH   A O   1 ? 
HETATM 4847 O O   . HOH   E 3 .   ? 7.133   -11.170 41.466 1.000 42.143 0 559 HOH   A O   1 ? 
HETATM 4848 O O   . HOH   E 3 .   ? -7.456  13.120  22.912 1.000 35.271 0 560 HOH   A O   1 ? 
HETATM 4849 O O   . HOH   E 3 .   ? 1.865   -4.786  10.197 1.000 42.421 0 561 HOH   A O   1 ? 
HETATM 4850 O O   . HOH   E 3 .   ? 21.285  -21.338 -6.417 1.000 40.463 0 562 HOH   A O   1 ? 
HETATM 4851 O O   . HOH   E 3 .   ? 18.058  4.012   12.341 1.000 26.029 0 563 HOH   A O   1 ? 
HETATM 4852 O O   . HOH   E 3 .   ? 11.418  -14.215 18.943 1.000 26.587 0 564 HOH   A O   1 ? 
HETATM 4853 O O   . HOH   F 3 .   ? -1.825  -40.690 8.959  1.000 28.970 0 501 HOH   B O   1 ? 
HETATM 4854 O O   . HOH   F 3 .   ? -7.444  -16.223 2.213  1.000 39.574 0 502 HOH   B O   1 ? 
HETATM 4855 O O   . HOH   F 3 .   ? -13.306 -25.379 7.793  1.000 15.203 0 503 HOH   B O   1 ? 
HETATM 4856 O O   . HOH   F 3 .   ? 0.914   -11.239 5.274  1.000 30.915 0 504 HOH   B O   1 ? 
HETATM 4857 O O   . HOH   F 3 .   ? 28.034  -18.178 36.463 1.000 17.243 0 505 HOH   B O   1 ? 
HETATM 4858 O O   . HOH   F 3 .   ? 22.705  -16.156 27.730 1.000 18.813 0 506 HOH   B O   1 ? 
HETATM 4859 O O   . HOH   F 3 .   ? -11.035 -31.045 20.835 1.000 31.162 0 507 HOH   B O   1 ? 
HETATM 4860 O O   . HOH   F 3 .   ? 26.294  -32.001 35.542 1.000 16.968 0 508 HOH   B O   1 ? 
HETATM 4861 O O   . HOH   F 3 .   ? 14.190  -24.884 21.112 1.000 12.524 0 509 HOH   B O   1 ? 
HETATM 4862 O O   . HOH   F 3 .   ? 25.047  -31.657 17.780 1.000 28.850 0 510 HOH   B O   1 ? 
HETATM 4863 O O   . HOH   F 3 .   ? 29.435  -18.482 44.894 1.000 24.945 0 511 HOH   B O   1 ? 
HETATM 4864 O O   . HOH   F 3 .   ? 35.400  -19.469 39.401 1.000 32.436 0 512 HOH   B O   1 ? 
HETATM 4865 O O   . HOH   F 3 .   ? 28.754  -20.820 51.193 1.000 15.242 0 513 HOH   B O   1 ? 
HETATM 4866 O O   . HOH   F 3 .   ? 5.320   -22.247 27.515 1.000 18.782 0 514 HOH   B O   1 ? 
HETATM 4867 O O   . HOH   F 3 .   ? 4.528   -22.671 16.385 1.000 12.496 0 515 HOH   B O   1 ? 
HETATM 4868 O O   . HOH   F 3 .   ? 31.227  -21.501 34.718 1.000 23.839 0 516 HOH   B O   1 ? 
HETATM 4869 O O   . HOH   F 3 .   ? 20.694  -38.358 32.885 1.000 24.461 0 517 HOH   B O   1 ? 
HETATM 4870 O O   . HOH   F 3 .   ? 18.843  -32.232 26.742 1.000 19.056 0 518 HOH   B O   1 ? 
HETATM 4871 O O   . HOH   F 3 .   ? 6.109   -32.648 -2.057 1.000 29.451 0 519 HOH   B O   1 ? 
HETATM 4872 O O   . HOH   F 3 .   ? 2.986   -10.997 7.929  1.000 28.342 0 520 HOH   B O   1 ? 
HETATM 4873 O O   . HOH   F 3 .   ? 3.267   -29.425 21.128 1.000 17.603 0 521 HOH   B O   1 ? 
HETATM 4874 O O   . HOH   F 3 .   ? 4.975   -9.744  3.530  1.000 39.840 0 522 HOH   B O   1 ? 
HETATM 4875 O O   . HOH   F 3 .   ? 7.644   -19.469 -2.992 1.000 28.597 0 523 HOH   B O   1 ? 
HETATM 4876 O O   . HOH   F 3 .   ? -3.927  -40.936 14.894 1.000 29.798 0 524 HOH   B O   1 ? 
HETATM 4877 O O   . HOH   F 3 .   ? 30.674  -32.628 21.643 1.000 35.861 0 525 HOH   B O   1 ? 
HETATM 4878 O O   . HOH   F 3 .   ? -8.875  -38.094 7.422  1.000 16.553 0 526 HOH   B O   1 ? 
HETATM 4879 O O   . HOH   F 3 .   ? 9.385   -22.913 6.666  1.000 24.578 0 527 HOH   B O   1 ? 
HETATM 4880 O O   . HOH   F 3 .   ? 5.234   -17.731 23.546 1.000 18.348 0 528 HOH   B O   1 ? 
HETATM 4881 O O   . HOH   F 3 .   ? -7.108  -39.968 6.759  1.000 13.673 0 529 HOH   B O   1 ? 
HETATM 4882 O O   . HOH   F 3 .   ? 4.144   -18.697 44.310 1.000 25.474 0 530 HOH   B O   1 ? 
HETATM 4883 O O   . HOH   F 3 .   ? 5.826   -15.332 13.814 1.000 29.338 0 531 HOH   B O   1 ? 
HETATM 4884 O O   . HOH   F 3 .   ? -9.092  -21.189 -2.411 1.000 15.483 0 532 HOH   B O   1 ? 
HETATM 4885 O O   . HOH   F 3 .   ? -3.627  -11.567 4.905  1.000 27.017 0 533 HOH   B O   1 ? 
HETATM 4886 O O   . HOH   F 3 .   ? -0.662  -27.157 23.871 1.000 19.483 0 534 HOH   B O   1 ? 
HETATM 4887 O O   . HOH   F 3 .   ? 31.167  -18.713 26.342 1.000 27.258 0 535 HOH   B O   1 ? 
HETATM 4888 O O   . HOH   F 3 .   ? 4.276   -26.415 26.933 1.000 34.378 0 536 HOH   B O   1 ? 
HETATM 4889 O O   . HOH   F 3 .   ? 32.433  -25.404 26.050 1.000 41.424 0 537 HOH   B O   1 ? 
HETATM 4890 O O   . HOH   F 3 .   ? -3.626  -40.177 18.530 1.000 28.769 0 538 HOH   B O   1 ? 
HETATM 4891 O O   . HOH   F 3 .   ? 11.919  -38.659 28.282 1.000 32.740 0 539 HOH   B O   1 ? 
HETATM 4892 O O   . HOH   F 3 .   ? 2.578   -10.791 3.188  1.000 28.841 0 540 HOH   B O   1 ? 
HETATM 4893 O O   . HOH   F 3 .   ? 33.583  -20.731 36.037 1.000 32.151 0 541 HOH   B O   1 ? 
HETATM 4894 O O   . HOH   F 3 .   ? 29.459  -31.790 23.628 1.000 34.786 0 542 HOH   B O   1 ? 
HETATM 4895 O O   . HOH   F 3 .   ? 18.272  -14.560 45.827 1.000 45.921 0 543 HOH   B O   1 ? 
HETATM 4896 O O   . HOH   F 3 .   ? 33.994  -16.845 41.966 1.000 45.670 0 544 HOH   B O   1 ? 
HETATM 4897 O O   . HOH   F 3 .   ? 4.885   -27.537 33.021 1.000 27.219 0 545 HOH   B O   1 ? 
HETATM 4898 O O   . HOH   F 3 .   ? 31.850  -16.725 34.086 1.000 40.916 0 546 HOH   B O   1 ? 
HETATM 4899 O O   . HOH   F 3 .   ? -10.870 -34.125 1.984  1.000 33.842 0 547 HOH   B O   1 ? 
# 
